Cluster ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count African_swine_fever_virus R-HSA-68886 M Phase 286/1415 395/10654 5.2233177622235474e-169 6.638836875786128e-166 2.809595133153929e-166 114791/10844/4000/115106/5718/23165/220134/4926/5689/5905/55839/11130/22995/55559/26271/79682/5684/5903/10403/5720/11065/54908/440145/55706/7175/6249/55143/11258/5579/5682/64151/22981/9631/246184/55055/25936/5525/9735/8636/7531/10142/80776/1459/1783/1058/5700/11190/122706/7321/5707/991/91754/401541/203068/79019/5526/54801/7532/55125/1454/348235/2801/80152/8697/5690/10382/5578/9212/5594/1063/8379/95681/5717/3619/9491/140609/23198/79172/10274/5861/5925/121441/147841/23244/7277/348995/23421/79441/143471/55920/79023/5706/9133/57122/5705/23636/79980/64105/10735/5116/23310/10197/6232/332/7443/23047/1780/10762/8881/9814/653784/10051/23122/5885/23511/5528/5048/1781/23354/7316/10213/5709/80321/10776/891/5695/5501/53371/57405/8655/4085/9738/1457/983/5714/55722/4957/23279/4927/9688/55166/10121/51433/9861/79902/9702/5566/3796/8615/5715/79959/54821/5519/84131/81876/5711/9183/9883/81565/5701/2491/5688/10112/1062/699/5687/2029/7846/23225/7840/5685/7283/5683/5698/5708/3320/8815/5692/22919/5686/5713/80097/1060/91687/119504/79003/8243/9126/10376/10426/5699/23397/5529/5710/22994/9663/11064/51143/9918/5702/10540/5520/10733/51529/85378/1069/8086/7324/83540/64900/5719/4001/64682/29945/10393/4751/11004/9232/5577/5704/6233/9700/5527/23175/51434/27175/80254/5716/701/7514/7311/9184/54930/9972/5518/25906/55844/10383/55835/54820/5347/113130/57551/54892/29922/8021/84643/9493/29882/6396/129401/9662/55142/80184/5694/23332/84930/1453/22897/25909/27229/64689/64946/9793/10726/5108/81930/55746/8481/5693/5721/140735/93323/5696/10592/10806/55755/5691/29781/8480/7314/996/5595/5515/1778/5516 286 African_swine_fever_virus R-HSA-69620 Cell Cycle Checkpoints 214/1415 293/10654 4.3254973169639865e-126 2.7488535449306134e-123 1.163331120509788e-123 5718/1017/220134/4172/6118/5689/5905/55839/11130/79682/9134/5684/5903/10403/5000/5720/11065/54908/8318/6249/55143/5682/9156/246184/55055/23594/25936/5525/9735/1763/7531/51512/1029/80776/1783/1058/5700/122706/7321/5707/991/401541/79019/5526/7532/8317/10971/348235/80152/8697/5690/9212/1063/51720/8379/5717/1027/3619/9491/23198/63967/79172/898/7533/2810/147841/348995/23421/4173/143471/545/55920/79023/5706/9133/472/57122/5705/79980/64105/10197/6232/332/580/1780/8881/23122/5528/5048/1781/7316/10213/5709/4174/891/993/5695/5501/890/57405/8655/4085/983/1026/84515/641/5714/4171/23279/55166/51433/9861/79902/4194/3796/5715/54821/5519/4998/9088/5711/9183/81565/7341/5701/10524/2491/5688/1062/699/5687/10926/5685/5683/5698/5708/5692/22919/5985/5686/5713/990/1060/91687/995/119504/79003/5699/5529/4175/5710/51143/1111/5702/7157/8900/51529/5984/7324/83540/5719/64682/29945/10393/11004/5704/6233/5527/51434/55388/5716/701/672/7514/5932/7158/23595/7311/9184/9025/5518/25906/54820/5347/57551/84643/5983/6117/29882/6396/7334/5001/5694/23332/7465/25909/64946/9793/10726/81930/55746/5693/5721/140735/5696/4999/5691/4176/7314/996/4193/5515/1778/5516 214 African_swine_fever_virus R-HSA-68877 Mitotic Prometaphase 173/1415 200/10654 9.717630576670374e-125 4.117036154316015e-122 1.7423541139223022e-122 114791/10844/115106/220134/4926/5905/55839/11130/22995/55559/79682/5903/10403/54908/440145/6249/55143/11258/64151/22981/55055/25936/5525/9735/8636/7531/10142/80776/1459/1783/1058/11190/991/401541/203068/79019/5526/54801/7532/55125/1454/348235/80152/10382/9212/1063/8379/95681/3619/79172/10274/121441/147841/23244/7277/348995/23421/79441/55920/79023/9133/57122/79980/64105/10735/5116/6232/332/23047/1780/9814/653784/10051/23122/5885/5528/5048/1781/23354/80321/891/5501/57405/8655/4085/9738/1457/983/55722/4957/23279/55166/10121/79902/9702/5566/3796/79959/54821/5519/84131/9183/81565/2491/1062/699/7846/7840/7283/3320/22919/80097/1060/91687/79003/8243/9126/10376/10426/23397/5529/22994/11064/51143/9918/10540/10733/85378/1069/83540/4751/11004/5577/5527/27175/80254/701/7514/9184/54930/5518/10383/55835/54820/5347/113130/57551/29922/84643/6396/9662/55142/80184/23332/1453/22897/25909/27229/64946/9793/10726/5108/81930/55746/8481/140735/93323/10592/10806/55755/5515/1778/5516 173 African_swine_fever_virus R-HSA-2555396 Mitotic Metaphase and Anaphase 172/1415 202/10654 1.6162361455344938e-121 5.135590352435854e-119 2.173412290442438e-119 4000/5718/220134/5689/5905/55839/11130/26271/79682/5684/5903/10403/5720/11065/54908/6249/55143/5682/246184/55055/25936/5525/9735/80776/1783/1058/5700/122706/7321/5707/991/401541/79019/5526/348235/80152/8697/5690/10382/9212/1063/8379/5717/3619/9491/23198/79172/10274/147841/23244/7277/348995/23421/143471/55920/79023/5706/57122/5705/79980/64105/10735/10197/6232/332/7443/23047/1780/8881/23122/5885/5528/5048/1781/7316/10213/5709/5695/5501/57405/8655/4085/5714/23279/55166/51433/9861/79902/3796/5715/54821/5519/5711/9183/81565/5701/2491/5688/1062/699/5687/7846/5685/5683/5698/5708/8815/5692/22919/5686/5713/1060/91687/119504/79003/8243/9126/10376/5699/5529/5710/51143/5702/5520/51529/7324/83540/5719/4001/64682/29945/10393/11004/9232/5704/6233/9700/5527/51434/5716/701/7514/7311/9184/5518/25906/10383/54820/5347/113130/57551/84643/29882/6396/5694/23332/25909/64946/9793/10726/81930/55746/5693/5721/140735/5696/5691/7314/996/5515/1778/5516 172 African_swine_fever_virus R-HSA-2467813 Separation of Sister Chromatids 166/1415 190/10654 3.6836128376534246e-121 9.363743833315005e-119 3.9627919158755793e-119 5718/220134/5689/5905/55839/11130/79682/5684/5903/10403/5720/11065/54908/6249/55143/5682/246184/55055/25936/5525/9735/80776/1783/1058/5700/122706/7321/5707/991/401541/79019/5526/348235/80152/8697/5690/10382/9212/1063/8379/5717/3619/9491/23198/79172/10274/147841/23244/7277/348995/23421/143471/55920/79023/5706/57122/5705/79980/64105/10735/10197/6232/332/23047/1780/8881/23122/5885/5528/5048/1781/7316/10213/5709/5695/5501/57405/8655/4085/5714/23279/55166/51433/9861/79902/3796/5715/54821/5519/5711/9183/81565/5701/2491/5688/1062/699/5687/7846/5685/5683/5698/5708/5692/22919/5686/5713/1060/91687/119504/79003/8243/9126/10376/5699/5529/5710/51143/5702/51529/7324/83540/5719/64682/29945/10393/11004/9232/5704/6233/9700/5527/51434/5716/701/7514/7311/9184/5518/25906/10383/54820/5347/113130/57551/84643/29882/6396/5694/23332/25909/64946/9793/10726/81930/55746/5693/5721/140735/5696/5691/7314/996/5515/1778/5516 166 African_swine_fever_virus R-HSA-68882 Mitotic Anaphase 171/1415 201/10654 1.1565682273799075e-120 2.4499970283331044e-118 1.0368532705107592e-118 4000/5718/220134/5689/5905/55839/11130/79682/5684/5903/10403/5720/11065/54908/6249/55143/5682/246184/55055/25936/5525/9735/80776/1783/1058/5700/122706/7321/5707/991/401541/79019/5526/348235/80152/8697/5690/10382/9212/1063/8379/5717/3619/9491/23198/79172/10274/147841/23244/7277/348995/23421/143471/55920/79023/5706/57122/5705/79980/64105/10735/10197/6232/332/7443/23047/1780/8881/23122/5885/5528/5048/1781/7316/10213/5709/5695/5501/57405/8655/4085/5714/23279/55166/51433/9861/79902/3796/5715/54821/5519/5711/9183/81565/5701/2491/5688/1062/699/5687/7846/5685/5683/5698/5708/8815/5692/22919/5686/5713/1060/91687/119504/79003/8243/9126/10376/5699/5529/5710/51143/5702/5520/51529/7324/83540/5719/4001/64682/29945/10393/11004/9232/5704/6233/9700/5527/51434/5716/701/7514/7311/9184/5518/25906/10383/54820/5347/113130/57551/84643/29882/6396/5694/23332/25909/64946/9793/10726/81930/55746/5693/5721/140735/5696/5691/7314/996/5515/1778/5516 171 African_swine_fever_virus R-HSA-453274 Mitotic G2-G2/M phases 167/1415 198/10654 1.6804708004193293e-116 3.0512548390470968e-114 1.2913091413748531e-114 114791/10844/8454/115106/5718/1017/5689/8945/22995/55559/5684/994/5720/4605/902/440145/2305/11258/5682/22981/8636/7531/51512/10142/5700/11190/122706/5707/203068/54801/7532/84962/55125/1454/22974/5690/10382/3161/1063/95681/5717/9491/23198/6500/121441/7277/79441/143471/5706/9133/5705/5116/10197/9814/653784/5048/1781/23354/7316/10213/728642/5709/80321/9978/1869/891/993/5695/890/8655/9738/4331/983/1026/6790/5714/55722/4957/10121/9861/9702/5566/5715/79959/5519/84131/9088/5711/5701/5688/5687/23291/7846/7840/5685/7283/5683/5698/5708/3320/5692/22919/984/5686/5713/80097/2033/995/10376/10426/5699/5710/22994/11064/5702/10540/5520/7157/10733/8900/85378/79866/1069/5719/4751/5577/5704/6233/27175/80254/5716/7514/7311/54930/5518/10133/10383/55835/54820/5347/29922/9662/55142/80184/5694/23332/1453/22897/7465/27229/9793/4218/5108/1022/8481/5693/5721/93323/5696/10806/55755/5691/5500/7314/5515/1778/5516 167 African_swine_fever_virus R-HSA-69275 G2/M Transition 166/1415 196/10654 2.1191986653888324e-116 3.366876879636507e-114 1.4248822605443334e-114 114791/10844/8454/115106/5718/1017/5689/8945/22995/55559/5684/994/5720/4605/902/440145/2305/11258/5682/22981/8636/7531/51512/10142/5700/11190/122706/5707/203068/54801/7532/84962/55125/1454/22974/5690/10382/3161/1063/95681/5717/9491/23198/6500/121441/7277/79441/143471/5706/9133/5705/5116/10197/9814/653784/5048/1781/23354/7316/10213/728642/5709/80321/9978/891/993/5695/890/8655/9738/4331/983/1026/6790/5714/55722/4957/10121/9861/9702/5566/5715/79959/5519/84131/9088/5711/5701/5688/5687/23291/7846/7840/5685/7283/5683/5698/5708/3320/5692/22919/984/5686/5713/80097/2033/995/10376/10426/5699/5710/22994/11064/5702/10540/5520/7157/10733/8900/85378/79866/1069/5719/4751/5577/5704/6233/27175/80254/5716/7514/7311/54930/5518/10133/10383/55835/54820/5347/29922/9662/55142/80184/5694/23332/1453/22897/7465/27229/9793/4218/5108/1022/8481/5693/5721/93323/5696/10806/55755/5691/5500/7314/5515/1778/5516 166 African_swine_fever_virus R-HSA-69242 S Phase 137/1415 161/10654 2.2695315587199484e-96 3.2050829012589494e-94 1.3564100894805776e-94 8454/5718/1017/4172/6118/5689/2237/9134/1019/5684/994/5000/5720/11065/902/8318/5682/246184/23594/1763/7027/5700/122706/7321/5707/57804/207/9837/8697/5690/5717/1027/9491/23198/6500/898/10274/5925/23244/4173/143471/5706/5705/10735/10197/3978/23047/8881/5934/5885/5557/7316/10213/5709/5422/9978/1869/4174/1875/993/5695/890/4331/1026/5425/84515/5714/5111/4171/4609/51433/9861/5715/4998/5711/2932/5701/5688/5687/5427/6502/5685/5683/5698/5708/5692/5985/5686/5713/990/119504/1874/8243/9126/595/5699/4175/5710/81620/5702/8900/51529/5984/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/23595/7311/25906/114799/51659/113130/157570/5983/6117/29882/5001/5981/5694/7465/1163/1022/5693/5721/5696/4999/5691/4176/7314/996 137 African_swine_fever_virus R-HSA-449147 Signaling by Interleukins 232/1415 461/10654 1.80096395724103e-86 2.289025189653349e-84 9.687290338422803e-85 5295/8454/3605/3557/7124/1147/5718/2308/834/1052/5689/3725/7291/5777/56300/8945/1326/596/5684/3562/5601/351/9252/5290/5720/1437/4790/6283/6885/6597/5606/5682/90865/5604/4215/5657/11213/7412/5700/6351/3578/122706/5707/27178/3593/3589/6775/207/246/5451/3684/9021/7422/29110/5690/3553/5594/8878/5717/2919/9491/23198/6500/3082/28512/5743/3091/941/23118/143471/4318/5706/4312/3383/5705/301/10197/8517/6657/6778/3576/4615/332/3662/5528/4313/7316/3565/10213/5709/9978/2920/5695/79155/6352/84868/3185/6774/4314/1435/7335/5970/4792/6850/1026/6348/9261/3718/1440/4793/3627/7133/5714/3606/177/6772/8807/8651/8809/4609/3146/7867/9861/3603/5566/149233/6364/5715/5519/64127/5711/7132/3552/1432/5701/5688/3567/5687/6950/3558/4067/3717/23291/4088/598/2247/836/5685/5683/5698/5708/3320/5602/5692/5686/5713/4843/2335/2534/3656/595/5699/5710/3458/3181/10454/6288/5702/998/7157/6648/942/5719/4001/3654/3563/7189/6285/5609/5704/6233/3716/84639/5716/85480/1385/2353/7311/3594/6347/3932/5518/240/1386/7040/3687/552900/51561/5599/5600/7334/6356/3600/5694/3312/3574/3559/3551/7297/6416/5608/3569/3162/4170/5693/1234/5721/5696/3586/5691/4791/3554/829/7314/28511/3596/5595/5515/59067/257397/3556/5516 232 African_swine_fever_virus R-HSA-69306 DNA Replication 112/1415 127/10654 2.0543873310457346e-82 2.3737511797810262e-80 1.0045855752769094e-80 8454/5718/1017/4172/6118/5689/2237/9134/5684/5000/5720/11065/8318/5682/246184/23594/1763/5700/122706/7321/5707/57804/8317/9837/8697/5690/5717/9491/23198/6500/898/4173/143471/5706/5705/10197/3978/8881/5557/7316/10213/5709/5422/9978/1869/4174/5695/890/5425/84515/5714/5111/4171/51433/9861/51053/5715/4998/5711/5701/5688/5687/10926/5427/6502/5685/5683/5698/5708/5692/5985/5686/5713/990/119504/5699/4175/5710/81620/5702/8900/51529/5984/7324/5719/64682/29945/10393/5704/6233/51434/55388/5716/51343/23595/7311/25906/51659/5983/6117/29882/5001/5981/5694/5693/5721/5696/4999/5691/4176/7314/996 112 African_swine_fever_virus R-HSA-69239 Synthesis of DNA 107/1415 119/10654 8.44761263457202e-81 8.947429715450865e-79 3.786605312514301e-79 8454/5718/1017/4172/6118/5689/2237/9134/5684/5000/5720/11065/8318/5682/246184/23594/1763/5700/122706/7321/5707/57804/9837/8697/5690/5717/9491/23198/6500/898/4173/143471/5706/5705/10197/3978/8881/5557/7316/10213/5709/5422/9978/4174/5695/890/5425/84515/5714/5111/4171/51433/9861/5715/4998/5711/5701/5688/5687/5427/6502/5685/5683/5698/5708/5692/5985/5686/5713/990/119504/5699/4175/5710/81620/5702/8900/51529/5984/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/23595/7311/25906/51659/5983/6117/29882/5001/5981/5694/5693/5721/5696/4999/5691/4176/7314/996 107 African_swine_fever_virus R-HSA-69618 Mitotic Spindle Checkpoint 103/1415 112/10654 3.0362211565624705e-80 2.968490069223769e-78 1.2562826000027713e-78 220134/5905/55839/11130/79682/5903/10403/11065/54908/6249/55143/246184/55055/25936/5525/9735/80776/1783/1058/7321/991/401541/79019/5526/348235/80152/8697/9212/1063/8379/3619/79172/147841/348995/23421/55920/79023/57122/79980/64105/6232/332/1780/8881/23122/5528/5048/1781/5501/57405/8655/4085/23279/55166/51433/79902/3796/54821/5519/9183/81565/2491/1062/699/22919/1060/91687/119504/79003/5529/51143/51529/7324/83540/64682/29945/10393/11004/5527/51434/701/7514/9184/5518/25906/54820/5347/57551/84643/29882/6396/23332/25909/64946/9793/10726/81930/55746/140735/996/5515/1778/5516 103 African_swine_fever_virus R-HSA-453279 Mitotic G1-G1/S phases 121/1415 149/10654 3.3247649663751436e-80 3.0184116230448627e-78 1.277409697607292e-78 8454/5718/1017/4172/6118/5689/25/26271/894/9134/1019/5684/5000/5720/4605/902/8318/5682/23594/1029/7027/5700/5707/8317/207/5690/5717/1027/9491/6500/7153/898/5925/4173/5706/5705/10197/5934/5557/7316/10213/5709/5422/1869/4174/891/1875/993/5695/890/4331/983/1026/84515/5933/5714/5111/6714/4171/4609/9861/51053/5715/5519/4998/5711/5701/5688/5687/10926/5427/4067/3717/6502/5685/5683/5698/5708/5692/5686/5713/990/1021/1874/595/5699/4175/5710/81620/5702/3065/5520/8900/896/5719/5704/6233/7298/55388/5716/23595/7311/5518/6117/5001/5694/7465/1163/1022/5693/5721/5696/4999/7083/5691/1028/4176/7314/5515/6241/5516 121 African_swine_fever_virus R-HSA-5620912 Anchoring of the basal body to the plasma membrane 94/1415 98/10654 5.244466407648057e-78 4.4438112027471205e-76 1.8806472521460755e-76 115106/22995/55559/79867/11258/22981/8636/7531/54903/10142/80776/11190/203068/54801/7532/55125/1454/10382/85302/51134/95681/121441/7277/79441/5116/54806/9814/91147/5048/1781/23354/80321/8766/22832/146057/8655/9738/79598/983/55722/4957/10121/9702/5566/79959/132320/347240/84131/7846/7840/7283/3320/22919/27077/22994/11064/4867/79600/10540/84902/10733/1069/4751/117177/5577/80254/57545/26005/54930/5518/26123/10383/55835/54820/5347/23322/9662/55142/80184/23332/1453/22897/9793/4218/5108/261734/8481/57787/93323/10806/51259/55755/9657/1778 94 African_swine_fever_virus R-HSA-69052 Switching of origins to a post-replicative state 89/1415 90/10654 6.275949896833262e-78 4.985457699296922e-76 2.1098752613696032e-76 8454/5718/1017/4172/5689/9134/5684/5000/5720/11065/5682/246184/23594/5700/122706/7321/5707/8697/5690/5717/9491/23198/6500/898/4173/143471/5706/5705/10197/8881/7316/10213/5709/9978/4174/5695/890/84515/5714/4171/51433/9861/5715/4998/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/990/119504/5699/4175/5710/81620/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/23595/7311/25906/29882/5001/5694/5693/5721/5696/4999/5691/4176/7314/996 89 African_swine_fever_virus R-HSA-69206 G1/S Transition 109/1415 131/10654 1.9286911757938785e-74 1.441980284961188e-72 6.102546073254934e-73 8454/5718/1017/4172/6118/5689/26271/9134/1019/5684/5000/5720/902/8318/5682/23594/7027/5700/5707/8317/207/5690/5717/1027/9491/6500/898/5925/4173/5706/5705/10197/5934/5557/7316/10213/5709/5422/1869/4174/891/1875/993/5695/890/4331/983/1026/84515/5933/5714/5111/4171/4609/9861/51053/5715/5519/4998/5711/5701/5688/5687/10926/5427/6502/5685/5683/5698/5708/5692/5686/5713/990/1874/595/5699/4175/5710/81620/5702/3065/8900/5719/5704/6233/7298/55388/5716/23595/7311/5518/6117/5001/5694/7465/1163/1022/5693/5721/5696/4999/7083/5691/4176/7314/5515/6241/5516 109 African_swine_fever_virus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 85/1415 86/10654 2.400207299069359e-74 1.60561235637745e-72 6.795046702628489e-73 8454/5718/1017/5689/8945/26271/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/9212/5717/9491/23198/6500/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/8556/7324/5719/64682/29945/10393/4751/9232/5704/6233/51434/5716/701/51343/7311/9184/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 85 African_swine_fever_virus R-HSA-453276 Regulation of mitotic cell cycle 85/1415 86/10654 2.400207299069359e-74 1.60561235637745e-72 6.795046702628489e-73 8454/5718/1017/5689/8945/26271/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/9212/5717/9491/23198/6500/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/8556/7324/5719/64682/29945/10393/4751/9232/5704/6233/51434/5716/701/51343/7311/9184/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 85 African_swine_fever_virus R-HSA-9020702 Interleukin-1 signaling 93/1415 103/10654 1.2368242461856785e-70 7.860018084509986e-69 3.326406262109904e-69 8454/3557/1147/5718/5689/8945/1326/5684/351/5720/4790/6283/6885/5682/5604/4215/11213/5700/122706/5707/5690/3553/8878/5717/9491/23198/6500/28512/23118/143471/5706/5705/10197/8517/4615/7316/10213/5709/9978/5695/79155/7335/5970/4792/4793/5714/177/3146/9861/5715/64127/5711/3552/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/3656/5699/5710/10454/6288/5702/5719/3654/7189/6285/5704/6233/5716/7311/7334/5694/3551/6416/5608/5693/5721/5696/5691/4791/3554/7314/28511/257397/3556 93 African_swine_fever_virus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 79/1415 80/10654 5.543217282605251e-69 3.354966269614893e-67 1.4198416197550293e-67 8454/5718/1017/5689/8945/26271/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/6500/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/701/51343/7311/9184/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 79 African_swine_fever_virus R-HSA-2500257 Resolution of Sister Chromatid Cohesion 103/1415 126/10654 8.11256963582785e-69 4.686852730516908e-67 1.9835038678985797e-67 220134/5905/55839/11130/79682/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/401541/79019/5526/348235/80152/10382/9212/1063/8379/3619/79172/10274/147841/23244/7277/348995/23421/55920/79023/9133/57122/79980/64105/10735/6232/332/23047/1780/23122/5885/5528/5048/1781/891/5501/57405/8655/4085/983/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/7846/22919/1060/91687/79003/8243/9126/10376/5529/51143/83540/11004/5527/701/7514/9184/5518/10383/54820/5347/113130/57551/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/5515/1778/5516 103 African_swine_fever_virus R-HSA-446652 Interleukin-1 family signaling 109/1415 140/10654 1.2859123128760572e-68 7.106063259415081e-67 3.007328109289086e-67 8454/3557/1147/5718/834/5689/5777/56300/8945/1326/5684/351/5720/4790/6283/6885/5682/90865/5604/4215/11213/5700/122706/5707/27178/29110/5690/3553/8878/5717/9491/23198/6500/28512/23118/143471/5706/5705/10197/8517/4615/7316/3565/10213/5709/9978/5695/79155/6774/7335/5970/4792/4793/5714/3606/177/8807/8809/3146/9861/5715/64127/5711/3552/5701/5688/5687/23291/4088/5685/5683/5698/5708/5692/5686/5713/3656/5699/5710/10454/6288/5702/5719/3654/7189/6285/5704/6233/84639/5716/7311/240/5599/7334/5694/3551/6416/5608/5693/5721/5696/5691/4791/3554/7314/28511/3596/257397/3556 109 African_swine_fever_virus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 83/1415 88/10654 4.047455404775504e-67 2.1434649247790276e-65 9.071270665966153e-66 8454/115106/8945/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/84962/55125/1454/10382/95681/6500/121441/7277/79441/9133/5116/9814/5048/1781/23354/7316/80321/891/8655/9738/983/6790/55722/4957/10121/9702/5566/79959/84131/23291/7846/7840/7283/3320/22919/22994/11064/10540/10733/79866/1069/4751/5577/6233/80254/7311/54930/5518/10133/10383/55835/54820/5347/9662/55142/80184/23332/1453/22897/9793/4218/5108/8481/93323/10806/55755/5500/7314/1778 83 African_swine_fever_virus R-HSA-141424 Amplification of signal from the kinetochores 87/1415 96/10654 1.9808061078856966e-66 9.683094473548925e-65 4.09794300052466e-65 220134/5905/55839/11130/79682/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/401541/79019/5526/348235/80152/9212/1063/8379/3619/79172/147841/348995/23421/55920/79023/57122/79980/64105/6232/332/1780/23122/5528/5048/1781/5501/57405/8655/4085/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/22919/1060/91687/79003/5529/51143/83540/11004/5527/701/7514/9184/5518/54820/5347/57551/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/5515/1778/5516 87 African_swine_fever_virus R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 87/1415 96/10654 1.9808061078856966e-66 9.683094473548925e-65 4.09794300052466e-65 220134/5905/55839/11130/79682/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/401541/79019/5526/348235/80152/9212/1063/8379/3619/79172/147841/348995/23421/55920/79023/57122/79980/64105/6232/332/1780/23122/5528/5048/1781/5501/57405/8655/4085/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/22919/1060/91687/79003/5529/51143/83540/11004/5527/701/7514/9184/5518/54820/5347/57551/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/5515/1778/5516 87 African_swine_fever_virus R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 79/1415 82/10654 4.70060909553632e-66 2.133740771580951e-64 9.030117473003983e-65 114791/10844/115106/22995/55559/440145/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/653784/5048/1781/23354/728642/80321/8655/9738/983/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/984/80097/10426/22994/11064/10540/10733/85378/1069/4751/5577/27175/80254/54930/5518/10383/55835/54820/5347/29922/9662/55142/80184/23332/1453/22897/27229/9793/5108/8481/93323/10806/55755/1778 79 African_swine_fever_virus R-HSA-380287 Centrosome maturation 79/1415 82/10654 4.70060909553632e-66 2.133740771580951e-64 9.030117473003983e-65 114791/10844/115106/22995/55559/440145/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/653784/5048/1781/23354/728642/80321/8655/9738/983/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/984/80097/10426/22994/11064/10540/10733/85378/1069/4751/5577/27175/80254/54930/5518/10383/55835/54820/5347/29922/9662/55142/80184/23332/1453/22897/27229/9793/5108/8481/93323/10806/55755/1778 79 African_swine_fever_virus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 75/1415 76/10654 2.053166672206714e-65 8.998533932326668e-64 3.808232920136591e-64 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/4751/9232/5704/6233/51434/5716/701/7311/9184/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 75 African_swine_fever_virus R-HSA-2262752 Cellular responses to stress 211/1415 479/10654 4.528469760256043e-65 1.9185616884284768e-63 8.119466833301185e-64 5718/1017/23165/3303/6118/5689/3725/6782/9134/1019/5684/5903/5601/5720/11065/4790/55706/7175/653361/5241/11258/5606/5682/9631/9448/3159/246184/112399/7531/1029/7027/1915/1783/5700/122706/7321/5707/2146/25828/84962/6045/7422/8697/5690/10382/9114/5594/9530/3308/5717/1027/9491/23198/898/10049/7295/5925/3091/7277/348995/1051/10013/143471/545/79023/5706/472/57122/5705/23636/79813/10197/3576/10671/1780/10762/8881/7001/847/23511/7323/1781/7316/10213/5709/9978/1869/5695/890/3305/53371/8655/6774/5970/1026/9261/6667/5714/23279/4927/9688/10121/7415/7867/51433/9861/79902/4194/7322/5715/5711/9883/3552/1432/2932/5701/10524/5688/1387/5687/7846/259217/23225/3310/2908/5685/5683/3309/5698/5708/3320/5602/5692/5686/5713/2033/23512/1021/119504/10376/5699/6009/5710/51143/3301/5702/10540/9531/7157/8453/8900/51529/6648/8086/7324/5719/4001/64682/29945/10393/8091/23112/5609/5704/6233/51434/2475/5716/3306/2353/51343/7311/367/9972/25906/10383/23411/8021/55662/6117/29882/5599/6396/129401/5600/5694/3312/4217/26523/3456/5052/405/6416/5608/3569/55746/5693/5721/140735/5696/5691/8480/10919/10728/829/7314/996/5595/4193/1778/23043 211 African_swine_fever_virus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 74/1415 75/10654 1.5984511611730054e-64 6.553649760809322e-63 2.7735434409487463e-63 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/4751/9232/5704/6233/51434/5716/701/7311/9184/25906/29882/5694/5693/5721/5696/5691/7314/996 74 African_swine_fever_virus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72/1415 73/10654 9.66427075751931e-63 3.838527541502201e-61 1.6244876174645947e-61 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/890/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/4751/5704/6233/51434/5716/701/7311/9184/25906/29882/5694/5693/5721/5696/5691/7314/996 72 African_swine_fever_virus R-HSA-8953897 Cellular responses to external stimuli 211/1415 493/10654 2.251168083063847e-62 8.670407980527726e-61 3.669368071596893e-61 5718/1017/23165/3303/6118/5689/3725/6782/9134/1019/5684/5903/5601/5720/11065/4790/55706/7175/653361/5241/11258/5606/5682/9631/9448/3159/246184/112399/7531/1029/7027/1915/1783/5700/122706/7321/5707/2146/25828/84962/6045/7422/8697/5690/10382/9114/5594/9530/3308/5717/1027/9491/23198/898/10049/7295/5925/3091/7277/348995/1051/10013/143471/545/79023/5706/472/57122/5705/23636/79813/10197/3576/10671/1780/10762/8881/7001/847/23511/7323/1781/7316/10213/5709/9978/1869/5695/890/3305/53371/8655/6774/5970/1026/9261/6667/5714/23279/4927/9688/10121/7415/7867/51433/9861/79902/4194/7322/5715/5711/9883/3552/1432/2932/5701/10524/5688/1387/5687/7846/259217/23225/3310/2908/5685/5683/3309/5698/5708/3320/5602/5692/5686/5713/2033/23512/1021/119504/10376/5699/6009/5710/51143/3301/5702/10540/9531/7157/8453/8900/51529/6648/8086/7324/5719/4001/64682/29945/10393/8091/23112/5609/5704/6233/51434/2475/5716/3306/2353/51343/7311/367/9972/25906/10383/23411/8021/55662/6117/29882/5599/6396/129401/5600/5694/3312/4217/26523/3456/5052/405/6416/5608/3569/55746/5693/5721/140735/5696/5691/8480/10919/10728/829/7314/996/5595/4193/1778/23043 211 African_swine_fever_virus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 71/1415 72/10654 7.505158217693267e-62 2.6497378040800396e-60 1.1213847512401342e-60 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/9212/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/9232/5704/6233/51434/5716/51343/7311/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 71 African_swine_fever_virus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 71/1415 72/10654 7.505158217693267e-62 2.6497378040800396e-60 1.1213847512401342e-60 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/890/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/701/7311/9184/25906/29882/5694/5693/5721/5696/5691/7314/996 71 African_swine_fever_virus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 71/1415 72/10654 7.505158217693267e-62 2.6497378040800396e-60 1.1213847512401342e-60 5718/1017/5689/9134/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/5717/9491/23198/898/143471/5706/5705/10197/8881/7316/10213/5709/5695/890/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/990/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 71 African_swine_fever_virus R-HSA-68949 Orc1 removal from chromatin 70/1415 71/10654 5.823515159879074e-61 2.0004561535692715e-59 8.466049065997744e-60 8454/5718/1017/4172/5689/5684/5000/5720/5682/23594/5700/122706/5707/5690/5717/9491/23198/6500/4173/143471/5706/5705/10197/7316/10213/5709/9978/4174/5695/890/84515/5714/4171/9861/5715/4998/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/990/5699/4175/5710/81620/5702/8900/5719/5704/6233/5716/23595/7311/5001/5694/5693/5721/5696/4999/5691/4176/7314 70 African_swine_fever_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 86/1415 101/10654 1.627561877714035e-60 5.443766175196153e-59 2.3038341260716675e-59 8454/1147/5718/5689/5170/8945/5684/5720/4790/6885/5682/4772/5700/122706/7321/5707/84433/5690/3553/5717/9491/23198/6500/23118/10892/143471/5706/5705/841/10197/8517/7316/10213/5709/5695/64581/9020/7335/5970/4792/6850/10768/8915/5714/6714/9861/7322/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/10454/5702/5719/7189/5704/6233/5580/5716/7311/5971/808/7334/5694/3551/801/5693/5721/5696/997/5691/4791/7314/805/257397 86 African_swine_fever_virus R-HSA-5663205 Infectious disease 179/1415 383/10654 9.726228232615059e-60 3.169752841962498e-58 1.3414581988842904e-58 3839/6158/5718/23165/3303/6875/5689/5905/6138/8945/3837/3838/2237/164/5684/5903/9349/4736/7852/5720/902/6206/6194/402569/6191/55706/7175/6128/5606/5682/9631/5604/1499/1938/3159/6129/5700/122706/5707/2959/5430/6222/6176/5690/6136/6878/6125/5717/4869/9491/23198/6500/6224/6146/51065/6154/348995/143471/6202/79023/5706/57122/5705/23636/10197/6232/3978/10762/23511/6164/7316/6155/10213/5709/9978/6218/5695/6872/2960/53371/292/4331/5714/6714/23279/4927/5605/6229/6231/9688/9861/79902/6130/5715/2962/3840/5711/6204/9883/5701/5688/6228/8812/23521/5687/23225/999/5685/5683/5698/5708/3320/8815/5692/5686/5713/2534/5699/6235/905/5710/2068/6181/6124/5702/5901/6207/8086/5719/3836/6139/5609/5704/6233/5716/7514/163/1025/9844/7311/6223/9972/3932/1213/6880/6908/6188/8021/7040/808/6396/6135/129401/904/5694/1175/1104/801/6882/6416/5608/1022/55746/5693/1234/5721/6137/5696/6170/5691/8480/6122/6133/2957/940/7314/5879/805/6230 179 African_swine_fever_virus R-HSA-8854518 AURKA Activation by TPX2 70/1415 73/10654 3.90307303974854e-58 1.2402014583800984e-56 5.248606113977643e-57 115106/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/22974/10382/3161/95681/121441/7277/79441/5116/9814/5048/1781/23354/80321/8655/9738/983/6790/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/22994/11064/10540/10733/1069/4751/5577/80254/54930/5518/10383/55835/54820/5347/9662/55142/80184/23332/1453/22897/9793/5108/8481/93323/10806/55755/1778 70 African_swine_fever_virus R-HSA-1169091 Activation of NF-kappaB in B cells 66/1415 67/10654 2.0930929469511727e-57 6.334097941845097e-56 2.680627809253256e-56 8454/1147/5718/5689/8945/5684/5720/4790/6885/5579/5966/5682/5700/122706/5707/84433/5690/5717/9491/23198/6500/10892/143471/5706/5705/10197/8517/7316/10213/5709/5695/5970/4792/4793/8915/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/4794/5694/3551/5693/5721/5696/5691/7314 66 African_swine_fever_virus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 66/1415 67/10654 2.0930929469511727e-57 6.334097941845097e-56 2.680627809253256e-56 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/9232/5704/6233/51434/5716/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 66 African_swine_fever_virus R-HSA-162909 Host Interactions of HIV factors 96/1415 129/10654 2.8402095726730066e-57 8.395131085738119e-56 3.5528692573706397e-56 5718/23165/5689/5905/8945/3837/164/5684/5903/5720/55706/7175/5682/9631/3159/5700/122706/5707/5690/5717/4869/9491/23198/6500/348995/143471/79023/5706/57122/5705/23636/10197/10762/23511/7316/10213/5709/9978/5695/53371/292/5714/23279/4927/9688/9861/79902/5715/5711/9883/5701/5688/5687/23225/5685/5683/5698/5708/8815/5692/5686/5713/2534/5699/5710/5702/5901/8086/5719/3836/5704/6233/5716/7514/163/1025/9844/7311/9972/3932/8021/6396/129401/904/5694/1175/1104/55746/5693/5721/5696/5691/8480/940/7314/5879 96 African_swine_fever_virus R-HSA-5621481 C-type lectin receptors (CLRs) 101/1415 142/10654 4.4771150443526055e-57 1.2932757321300367e-55 5.473219587713353e-56 8454/1147/5718/5689/5170/8945/4586/5684/9252/4893/5720/4790/6885/5682/4772/5700/122706/7321/5707/5567/4584/84433/5690/3553/5568/5717/9491/23198/6500/23118/10892/143471/5706/5705/841/10197/8517/7316/10213/5709/5695/64581/9020/7335/5970/4792/6850/10768/8915/5714/6714/9861/5566/7322/5715/5711/5701/5688/1387/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/2534/2033/5699/5710/10454/5702/5894/5719/7189/5704/6233/5580/5716/7311/5971/808/3845/7334/5694/3265/3551/5058/801/5693/5721/5696/997/5691/4791/7314/805/257397 101 African_swine_fever_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 97/1415 134/10654 5.460783726950884e-56 1.5423680259899053e-54 6.527392946133105e-55 5295/8454/1147/5718/5689/5170/3725/8945/5684/5601/4893/5290/5720/4790/6885/5682/4772/5700/122706/7321/5707/84433/5690/5594/5717/4214/9491/23198/6500/23118/10892/143471/5706/5705/10197/8517/7316/10213/5709/5695/7335/5970/4792/6850/10768/8915/5714/9861/7322/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5602/5692/5686/5713/2534/5699/5710/10454/5702/5719/7189/5609/5704/6233/5716/2353/7311/808/3845/5599/7334/5694/3265/3551/5058/801/6416/5693/5721/5696/997/5691/7314/5879/5595/805/257397 97 African_swine_fever_virus R-HSA-380259 Loss of Nlp from mitotic centrosomes 67/1415 70/10654 1.6664688315254867e-55 4.5065572018487095e-54 1.9072017310403667e-54 115106/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/5048/1781/23354/80321/8655/9738/983/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/22994/11064/10540/10733/1069/4751/5577/80254/54930/5518/10383/55835/54820/5347/9662/55142/80184/23332/1453/22897/9793/5108/8481/93323/10806/55755/1778 67 African_swine_fever_virus R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 67/1415 70/10654 1.6664688315254867e-55 4.5065572018487095e-54 1.9072017310403667e-54 115106/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/5048/1781/23354/80321/8655/9738/983/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/22994/11064/10540/10733/1069/4751/5577/80254/54930/5518/10383/55835/54820/5347/9662/55142/80184/23332/1453/22897/9793/5108/8481/93323/10806/55755/1778 67 African_swine_fever_virus R-HSA-69002 DNA Replication Pre-Initiation 75/1415 85/10654 2.5405264023969658e-55 6.727102203013633e-54 2.846949543036951e-54 5718/1017/4172/6118/5689/5684/5000/5720/8318/5682/23594/5700/122706/5707/8317/5690/5717/9491/23198/4173/143471/5706/5705/10197/5557/7316/10213/5709/5422/1869/4174/5695/84515/5714/4171/9861/51053/5715/4998/5711/5701/5688/5687/10926/5427/5685/5683/5698/5708/5692/5686/5713/990/5699/4175/5710/81620/5702/5719/5704/6233/55388/5716/23595/7311/6117/5001/5694/5693/5721/5696/4999/5691/4176/7314 75 African_swine_fever_virus R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 79/1415 94/10654 9.959916881340432e-55 2.583480480853814e-53 1.093344259154664e-53 114791/10844/115106/4926/22995/55559/440145/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/653784/5048/1781/23354/80321/8655/9738/983/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/80097/10376/10426/22994/11064/10540/10733/85378/1069/4751/5577/27175/80254/54930/5518/10383/55835/54820/5347/29922/9662/55142/80184/23332/1453/22897/27229/9793/5108/8481/93323/10806/55755/1778 79 African_swine_fever_virus R-HSA-2871837 FCERI mediated NF-kB activation 73/1415 82/10654 1.6895768766869002e-54 4.2949044205381e-53 1.8176290189200126e-53 8454/1147/5718/5689/5170/8945/5684/5720/4790/6885/5682/5700/122706/7321/5707/84433/5690/5717/9491/23198/6500/23118/10892/143471/5706/5705/10197/8517/7316/10213/5709/5695/7335/5970/4792/8915/5714/9861/7322/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/10454/5702/5719/7189/5704/6233/5716/7311/7334/5694/3551/5693/5721/5696/997/5691/7314/257397 73 African_swine_fever_virus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 62/1415 63/10654 7.419171309537382e-54 1.8489738694945123e-52 7.824967057117859e-53 5718/5689/5684/5720/11065/5682/246184/5700/7321/5707/8697/5690/5717/9491/5706/5705/10197/8881/7316/10213/5709/5695/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 62 African_swine_fever_virus R-HSA-68867 Assembly of the pre-replicative complex 65/1415 68/10654 9.389338950730124e-54 2.2949711166111516e-52 9.7124538538929e-53 5718/4172/5689/5684/5000/5720/5682/23594/5700/122706/5707/5690/5717/9491/23198/4173/143471/5706/5705/10197/7316/10213/5709/1869/4174/5695/84515/5714/4171/9861/51053/5715/4998/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/990/5699/4175/5710/81620/5702/5719/5704/6233/5716/23595/7311/5001/5694/5693/5721/5696/4999/5691/4176/7314 65 African_swine_fever_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 73/1415 83/10654 1.22678576377359e-53 2.9419711429362885e-52 1.245059633144597e-52 8454/1147/5718/5689/8945/5684/4893/5720/4790/6885/5579/5966/5682/4772/5700/122706/5707/84433/5690/5717/9491/23198/6500/10892/143471/5706/5705/10197/8517/7316/10213/5709/5695/5970/4792/4793/8915/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/4794/808/3845/5694/3265/3551/801/5693/5721/5696/5691/7314/805 73 African_swine_fever_virus R-HSA-5663220 RHO GTPases Activate Formins 97/1415 140/10654 3.798579066775723e-53 8.940729618281378e-52 3.783769791661587e-52 220134/5905/55839/11130/79682/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/401541/79019/5526/348235/80152/10382/9212/1063/6722/8379/3619/79172/147841/7277/348995/23421/55920/79023/57122/79980/64105/6232/332/1780/23122/5528/5048/1781/5501/57405/8655/4085/6714/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/7846/22919/1060/91687/79003/10376/5529/51143/998/83540/11004/5527/701/7514/9184/5518/10383/54820/5347/57551/60/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/5879/5515/1778/5516 97 African_swine_fever_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 73/1415 85/10654 5.078156232504863e-52 1.1735157402752148e-50 4.966388200593273e-51 8454/5718/1017/5689/9134/1019/5684/994/5720/902/5682/7027/5700/5707/207/5690/5717/1027/9491/6500/898/5925/5706/5705/10197/5934/7316/10213/5709/1869/1875/993/5695/890/4331/1026/5714/4609/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/1874/595/5699/5710/5702/8900/5719/5704/6233/5716/51343/7311/5694/7465/1163/1022/5693/5721/5696/5691/7314 73 African_swine_fever_virus R-HSA-69202 Cyclin E associated events during G1/S transition 71/1415 83/10654 2.315714206483602e-50 5.2558442079297466e-49 2.224304435175039e-49 8454/5718/1017/5689/9134/1019/5684/5720/902/5682/7027/5700/5707/207/5690/5717/1027/9491/6500/898/5925/5706/5705/10197/5934/7316/10213/5709/1869/1875/993/5695/890/4331/1026/5714/4609/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/1874/595/5699/5710/5702/8900/5719/5704/6233/5716/7311/5694/7465/1163/1022/5693/5721/5696/5691/7314 71 African_swine_fever_virus R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 58/1415 59/10654 2.5923802000559516e-50 5.7805530425809025e-49 2.4463643254452287e-49 5718/5689/5684/5000/5720/5682/23594/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/84515/5714/9861/51053/5715/4998/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/990/5699/5710/81620/5702/5719/5704/6233/5716/23595/7311/5001/5694/5693/5721/5696/4999/5691/7314 58 African_swine_fever_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 76/1415 94/10654 3.1835085671547965e-50 6.976274808368529e-49 2.952400867179857e-49 8454/1147/3665/3725/11035/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/7321/8737/29110/5594/6500/28512/330/23118/841/8517/7098/5528/7323/7316/79155/7335/5970/4792/9261/4793/177/3146/7867/7322/5519/64127/1432/329/23291/5602/3656/10454/6288/3661/3654/7189/6285/5609/6233/10010/1385/2353/7311/5518/7187/1386/8772/9641/5599/5600/7334/3551/6416/5608/4791/7314/28511/5595/5515/257397/5516 76 African_swine_fever_virus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 79/1415 102/10654 1.5317834777724895e-49 3.299825085167515e-48 1.3965055435178272e-48 8454/8792/7124/1147/5718/5689/8945/4050/5684/8744/5720/7186/5682/5700/122706/5707/8600/5690/5717/9491/23198/6500/330/143471/5706/8764/5705/10197/10673/7316/10213/5709/5695/9020/3604/7133/5714/9861/5715/5711/7132/5701/5688/329/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/4049/8740/5704/6233/5716/7311/5971/7293/115650/7187/51330/958/5694/5693/5721/8742/5696/5691/4791/959/7314/4055 79 African_swine_fever_virus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 58/1415 60/10654 6.797975191393055e-49 1.4400377447100955e-47 6.094325127722546e-48 8454/5718/1017/5689/9134/1019/5684/5720/5682/5700/5707/5690/5717/1027/9491/6500/898/5706/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/595/5699/5710/5702/8900/5719/5704/6233/5716/7311/5694/1163/5693/5721/5696/5691/7314 58 African_swine_fever_virus R-HSA-69615 G1/S DNA Damage Checkpoints 62/1415 68/10654 6.583667787747925e-48 1.3717773374143627e-46 5.805443036305763e-47 5718/1017/5689/9134/5684/5720/5682/1029/5700/122706/5707/5690/5717/1027/9491/23198/898/143471/5706/472/5705/10197/7316/10213/5709/993/5695/890/1026/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/7157/8900/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314/4193 62 African_swine_fever_virus R-HSA-69481 G2/M Checkpoints 102/1415 168/10654 1.1619624497139846e-47 2.3820230219136686e-46 1.0080862679182448e-46 5718/1017/4172/6118/5689/5684/5000/5720/8318/5682/9156/23594/1763/7531/51512/5700/122706/5707/7532/8317/10971/5690/51720/5717/9491/23198/63967/7533/2810/4173/143471/545/5706/9133/472/5705/10197/580/7316/10213/5709/4174/891/993/5695/983/84515/641/5714/4171/9861/5715/4998/9088/5711/7341/5701/10524/5688/5687/10926/5685/5683/5698/5708/5692/5985/5686/5713/990/995/5699/4175/5710/1111/5702/7157/5984/5719/5704/6233/55388/5716/672/5932/7158/23595/7311/9025/5983/6117/7334/5001/5694/7465/5693/5721/5696/4999/5691/4176/7314 102 African_swine_fever_virus R-HSA-166166 MyD88-independent TLR4 cascade 76/1415 99/10654 3.4685467637185067e-47 6.8883170885722215e-46 2.9151766385857843e-46 8454/1147/3665/3725/11035/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/7321/8737/29110/5594/6500/28512/330/23118/841/7099/8517/5528/7323/7316/79155/7335/5970/4792/9261/4793/177/3146/7867/7322/5519/64127/1432/329/23291/5602/3656/10454/6288/3661/3654/7189/6285/5609/6233/10010/1385/2353/7311/5518/7187/1386/8772/9641/5599/5600/7334/3551/6416/5608/4791/7314/28511/5595/5515/257397/5516 76 African_swine_fever_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 76/1415 99/10654 3.4685467637185067e-47 6.8883170885722215e-46 2.9151766385857843e-46 8454/1147/3665/3725/11035/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/7321/8737/29110/5594/6500/28512/330/23118/841/7099/8517/5528/7323/7316/79155/7335/5970/4792/9261/4793/177/3146/7867/7322/5519/64127/1432/329/23291/5602/3656/10454/6288/3661/3654/7189/6285/5609/6233/10010/1385/2353/7311/5518/7187/1386/8772/9641/5599/5600/7334/3551/6416/5608/4791/7314/28511/5595/5515/257397/5516 76 African_swine_fever_virus R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 54/1415 55/10654 8.92459755477641e-47 1.7260885005270977e-45 7.304908888727045e-46 8454/5718/5689/8945/26271/5684/5720/5682/5700/122706/5707/991/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/51343/7311/5694/5693/5721/5696/5691/7314 54 African_swine_fever_virus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 57/1415 60/10654 8.963166092430248e-47 1.7260885005270977e-45 7.304908888727045e-46 8454/1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/9020/5970/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5971/5694/5693/5721/5696/5691/4791/7314 57 African_swine_fever_virus R-HSA-69563 p53-Dependent G1 DNA Damage Response 60/1415 66/10654 3.3407533438479885e-46 6.244261029457049e-45 2.642608295211025e-45 5718/1017/5689/9134/5684/5720/5682/1029/5700/122706/5707/5690/5717/1027/9491/23198/898/143471/5706/472/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/8900/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314/4193 60 African_swine_fever_virus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 60/1415 66/10654 3.3407533438479885e-46 6.244261029457049e-45 2.642608295211025e-45 5718/1017/5689/9134/5684/5720/5682/1029/5700/122706/5707/5690/5717/1027/9491/23198/898/143471/5706/472/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/8900/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314/4193 60 African_swine_fever_virus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 56/1415 59/10654 6.639373562072921e-46 1.2229918546948814e-44 5.175774050677746e-45 8454/1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/9020/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5971/5694/5693/5721/5696/5691/4791/7314 56 African_swine_fever_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 80/1415 112/10654 1.470840586144194e-45 2.670626264270387e-44 1.13022487145817e-44 5295/8454/1147/5718/5689/5777/8945/5684/4893/5720/4790/6885/5579/5966/5682/4772/5700/122706/5707/84433/5690/5717/9491/23198/6500/930/10892/143471/5706/5705/10197/8517/7316/10213/5709/5695/5970/4792/6850/10768/4793/8915/5714/9861/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/2534/5699/5710/5702/5719/5704/6233/5716/7311/4794/808/3845/5694/3265/3551/801/5693/5721/5696/5691/7314/805 80 African_swine_fever_virus R-HSA-5357801 Programmed Cell Death 104/1415 181/10654 2.139660480230551e-45 3.830293620243704e-44 1.6210029731620632e-44 4000/5718/5689/11035/3837/596/5684/5720/7186/5682/1499/7531/1029/7027/842/5700/122706/5707/8737/7532/207/10971/5690/5594/10059/5717/9491/23198/63967/355/330/7533/2810/143471/5706/5705/841/10197/7099/7316/10213/5709/1869/5695/8655/7082/6774/5339/5714/8797/3146/9861/5715/5711/5701/5688/329/5687/1832/999/598/836/5685/5683/5698/5708/5692/5686/5713/8837/5699/4137/5710/3002/5702/7157/8626/5719/4001/3836/197259/5704/6233/5580/5716/6093/7311/7161/8772/331/5599/8717/7159/5694/637/8743/5693/5721/140735/5696/3148/5691/7314/5595 104 African_swine_fever_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 86/1415 129/10654 4.482017784720554e-45 7.869396419689381e-44 3.330375229169965e-44 8454/1147/3665/3725/11035/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/11213/7321/8737/3684/29110/5594/1785/4214/6500/28512/330/51295/23118/10333/841/7099/8517/4615/5528/7323/7316/79155/7335/5970/4792/7096/9261/4793/177/8651/3146/7867/7322/5519/64127/1432/329/23291/5602/3656/10454/6288/3661/3654/7189/6285/5609/6233/10010/1385/2353/7311/5518/7187/1386/8772/9641/5599/5600/7334/7097/3551/6416/5608/4791/7314/28511/5595/5515/257397/5516 86 African_swine_fever_virus R-HSA-202424 Downstream TCR signaling 74/1415 98/10654 4.5197949538735235e-45 7.869396419689381e-44 3.330375229169965e-44 5295/8454/1147/5718/5689/5170/8945/5684/5290/5720/4790/6885/5682/5700/122706/7321/5707/84433/5690/5717/9491/23198/6500/23118/10892/143471/5706/5705/10197/8517/7316/10213/5709/5695/7335/5970/4792/8915/5714/9861/7322/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5728/5699/5710/5702/5719/7189/5704/6233/5716/7311/3932/7334/5694/3551/5693/5721/5696/997/5691/7314 74 African_swine_fever_virus R-HSA-5610780 Degradation of GLI1 by the proteasome 56/1415 60/10654 8.704217090169103e-45 1.4556657791585434e-43 6.160463896227717e-44 8454/5718/5689/8945/5684/5720/2735/5682/5700/122706/5707/5567/5690/5568/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5566/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 56 African_swine_fever_virus R-HSA-5610783 Degradation of GLI2 by the proteasome 56/1415 60/10654 8.704217090169103e-45 1.4556657791585434e-43 6.160463896227717e-44 8454/5718/5689/8945/5684/5720/5682/5700/122706/5707/5567/5690/5568/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5566/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 56 African_swine_fever_virus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 56/1415 60/10654 8.704217090169103e-45 1.4556657791585434e-43 6.160463896227717e-44 8454/5718/5689/8945/5684/5720/5682/5700/122706/5707/5567/5690/5568/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5566/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 56 African_swine_fever_virus R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 51/1415 52/10654 3.970562977877156e-44 6.554007201145279e-43 2.7736947118184923e-43 5718/5689/1019/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/595/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 African_swine_fever_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 62/1415 73/10654 1.0930565653945897e-43 1.7811216597647737e-42 7.537812482005875e-43 8454/5718/5689/7291/5684/5720/5682/5700/122706/5707/10273/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/865/5695/5714/6772/2099/9861/5715/5711/2932/5701/5688/5687/6502/2908/5685/5683/5698/5708/5692/5686/5713/55294/5699/5710/5702/5719/5704/6233/5716/7311/860/5694/5693/5721/5696/5691/10891/7314 62 African_swine_fever_virus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 52/1415 54/10654 1.2283797754342597e-43 1.9762920184518277e-42 8.363785013283235e-43 8454/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/6790/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 52 African_swine_fever_virus R-HSA-5687128 MAPK6/MAPK4 signaling 69/1415 89/10654 2.0043122595489172e-43 3.184351102358342e-42 1.3476362692493379e-42 5718/2308/5689/27161/3725/5684/5720/5682/5700/10642/122706/5707/5567/5690/5568/5717/9491/3315/23198/143471/5706/5705/10197/7316/10213/5709/5695/983/5597/5714/4609/9861/5566/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/8555/5702/998/8556/896/5719/23112/5704/6233/5716/7514/7311/5694/26523/5058/8202/5693/5721/5696/5691/7314/5879 69 African_swine_fever_virus R-HSA-109581 Apoptosis 101/1415 178/10654 2.0430938965916473e-43 3.205891780948128e-42 1.3567524121615749e-42 4000/5718/5689/3837/596/5684/5720/7186/5682/1499/7531/1029/7027/842/5700/122706/5707/8737/7532/207/10971/5690/5594/10059/5717/9491/23198/63967/355/7533/2810/143471/5706/5705/841/10197/7099/7316/10213/5709/1869/5695/8655/7082/6774/5339/5714/8797/3146/9861/5715/5711/5701/5688/329/5687/1832/999/598/836/5685/5683/5698/5708/5692/5686/5713/8837/5699/4137/5710/3002/5702/7157/8626/5719/4001/3836/5704/6233/5580/5716/6093/7311/7161/8772/331/5599/8717/7159/5694/637/8743/5693/5721/140735/5696/3148/5691/7314/5595 101 African_swine_fever_virus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 53/1415 56/10654 2.673538864380389e-43 4.143985239789603e-42 1.7537591266988173e-42 5718/3303/5689/5684/5720/5682/5700/122706/5707/5690/3184/5717/9491/3315/23198/26986/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/3312/5693/5721/5696/5691/7314 53 African_swine_fever_virus R-HSA-162906 HIV Infection 117/1415 233/10654 6.534699759572775e-43 1.0006751077610839e-41 4.234916394599477e-42 5718/23165/6875/5689/5905/8945/3837/2237/164/5684/5903/7852/5720/902/55706/7175/5682/9631/3159/5700/122706/5707/2959/5430/5690/6878/5717/4869/9491/23198/6500/348995/143471/79023/5706/57122/5705/23636/10197/3978/10762/23511/7316/10213/5709/9978/5695/6872/2960/53371/292/4331/5714/23279/4927/9688/9861/79902/5715/2962/5711/9883/5701/5688/8812/5687/23225/5685/5683/5698/5708/8815/5692/5686/5713/2534/5699/905/5710/2068/5702/5901/8086/5719/3836/5704/6233/5716/7514/163/1025/9844/7311/9972/3932/6880/6908/8021/6396/129401/904/5694/1175/1104/6882/1022/55746/5693/1234/5721/5696/5691/8480/2957/940/7314/5879 117 African_swine_fever_virus R-HSA-69541 Stabilization of p53 53/1415 57/10654 3.329319581175327e-42 5.037577604373621e-41 2.1319327142613936e-41 5718/5689/5684/5720/5682/1029/5700/122706/5707/5690/5717/9491/23198/143471/5706/472/5705/10197/7316/10213/5709/5695/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314/4193 53 African_swine_fever_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 65/1415 82/10654 4.634708050557915e-42 6.930251685010718e-41 2.9329236084645137e-41 8454/5718/5689/8945/5684/5720/5682/1499/5525/5700/122706/5707/5526/5690/5717/9491/23198/6500/143471/5706/5705/10197/5528/7316/10213/5709/9978/5695/5714/9861/5715/5519/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5529/5710/5702/3065/7088/5719/5704/6233/5527/5716/7311/5518/5694/5693/5721/5696/5691/7314/5515/5516 65 African_swine_fever_virus R-HSA-180534 Vpu mediated degradation of CD4 50/1415 52/10654 6.872625096865309e-42 9.705673886795343e-41 4.1074987421031266e-41 5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 African_swine_fever_virus R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/1415 52/10654 6.872625096865309e-42 9.705673886795343e-41 4.1074987421031266e-41 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/472/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 African_swine_fever_virus R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 50/1415 52/10654 6.872625096865309e-42 9.705673886795343e-41 4.1074987421031266e-41 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 African_swine_fever_virus R-HSA-69610 p53-Independent DNA Damage Response 50/1415 52/10654 6.872625096865309e-42 9.705673886795343e-41 4.1074987421031266e-41 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 African_swine_fever_virus R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 50/1415 52/10654 6.872625096865309e-42 9.705673886795343e-41 4.1074987421031266e-41 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 African_swine_fever_virus R-HSA-168898 Toll-like Receptor Cascades 92/1415 155/10654 7.173261785916398e-42 1.0018918384505212e-40 4.2400656710275066e-41 54106/8454/1147/3665/3725/11035/8945/1326/5601/351/9252/81793/4790/6283/6885/5606/5604/11213/7321/8737/3684/29110/5594/1785/4214/6500/28512/330/51295/23118/10333/841/7099/8517/4615/7098/7100/5528/7323/7316/79155/7335/5970/4792/7096/9261/4793/177/8651/3146/7867/7322/5519/64127/1432/329/23291/5602/3656/10454/6288/3661/3654/7189/6285/5609/6233/51311/10010/1385/2353/7311/5518/7187/1386/8772/9641/5599/5600/7334/7097/3551/6416/5608/4791/51284/7314/28511/5595/5515/257397/5516 92 African_swine_fever_virus R-HSA-8878166 Transcriptional regulation by RUNX2 80/1415 121/10654 1.4257992148899612e-41 1.9697726110055875e-40 8.336194494379521e-41 8454/5718/8493/5689/7291/25/1019/5684/8841/5720/5682/5700/122706/5707/10273/207/5690/5594/5717/9491/23198/6500/5925/10013/143471/5706/5705/10197/7316/10213/5709/9978/891/865/5695/983/1026/5714/6772/6714/2099/9861/4089/5715/5711/2932/5701/5688/5687/6502/4322/2908/5685/5683/5698/5708/5692/5686/5713/595/55294/5699/5710/5702/861/5719/5704/6233/5716/7311/367/860/5694/5693/5721/5696/5691/10891/7314/5595 80 African_swine_fever_virus R-HSA-9604323 Negative regulation of NOTCH4 signaling 51/1415 54/10654 1.4461659576138199e-41 1.970352409396563e-40 8.338648235551317e-41 8454/5718/5689/5684/5720/5682/5700/5707/207/5690/5717/9491/6500/5706/5705/10197/10460/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/55294/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 African_swine_fever_virus R-HSA-9006925 Intracellular signaling by second messengers 135/1415 305/10654 1.457223654471101e-41 1.970352409396563e-40 8.338648235551317e-41 5295/1147/5718/2308/5689/5170/27161/3725/3838/5684/8841/5290/5720/5682/90865/5468/5525/1459/842/5700/122706/5707/5567/2146/8870/5526/10273/207/6045/5690/5578/5594/2069/5568/5717/1027/9491/23198/930/3082/941/143471/5706/2064/57761/5705/10197/4615/5528/7316/10213/5709/1950/5695/1457/1026/10768/5714/6714/2099/9861/5566/10014/5715/5519/5711/1958/2932/5701/5688/5687/5576/2247/5685/29851/5683/5698/5708/5880/5692/5686/5713/2534/23512/5728/5699/6009/5529/5710/6615/3630/5702/3066/3065/7157/23028/942/5719/3654/7189/5371/23112/5577/5704/6233/5527/5580/2475/5716/1385/7311/3932/5518/1386/1956/5581/331/808/5694/26523/7874/801/5693/5721/5696/5691/940/7314/5879/5595/4193/805/5515/3556/5516 135 African_swine_fever_virus R-HSA-376176 Signaling by ROBO receptors 111/1415 218/10654 1.742266673067951e-41 2.3309694120730167e-40 9.86480077493322e-41 10921/6158/5718/5689/6138/25/5684/9349/4736/7852/5720/6206/6194/6191/6128/5682/6129/5700/122706/5707/5567/56924/6222/6176/5690/6136/5578/5568/6125/5717/9491/23198/6224/6146/51065/6154/26986/143471/6202/5706/5705/3670/10197/6232/8829/23122/6164/7316/6155/10213/5709/9978/6218/5695/5714/6714/6229/6231/9861/5566/6130/5715/5711/6204/5701/5688/6228/23521/5687/5576/5685/1605/5683/5698/5708/5692/5686/5713/5699/6235/5710/6181/6124/5702/998/8453/6207/5719/6139/5704/6233/5716/7311/6223/6188/6135/5694/23332/5058/5693/5721/6137/5696/6170/5691/6122/6133/7314/5879/6387/6230 111 African_swine_fever_virus R-HSA-195258 RHO GTPase Effectors 140/1415 327/10654 4.64384597903048e-41 6.1482585826538964e-40 2.6019794904436133e-40 220134/5170/5905/55839/11130/25/79682/5590/5903/10403/54908/6249/55143/653361/5579/1499/55055/25936/5525/9735/7531/80776/1783/1058/991/401541/79019/5526/4627/7532/10971/348235/80152/4771/10382/5578/9212/5594/1063/6722/8379/1027/3619/10627/79172/7533/2810/147841/7277/348995/23421/55920/79023/57122/79980/64105/6232/332/1780/23122/5528/5048/1781/5501/57405/8655/4085/5585/6714/23279/55166/79902/3796/54821/5519/9183/1432/81565/4637/2491/1062/699/7846/999/5880/22919/79784/9475/1060/91687/995/79003/10376/5529/51143/998/23028/10788/83540/11004/5527/5580/7454/701/9055/7514/6093/9184/57120/9928/367/5518/10383/54820/5347/57551/60/5300/84643/808/6396/5600/23332/25909/5058/801/64946/9793/10726/81930/55746/140735/5500/5879/4221/5595/805/5515/1778/5516 140 African_swine_fever_virus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 62/1415 77/10654 6.329130522865878e-41 8.29311844800261e-40 3.5096969041611114e-40 5718/5689/5684/5720/5682/51512/5700/122706/5707/5690/10382/5717/9491/23198/7277/143471/5706/9133/5705/10197/7316/10213/5709/891/5695/983/1026/5714/9861/5715/5711/5701/5688/5687/7846/5685/5683/5698/5708/3320/5692/22919/5686/5713/10376/5699/5710/5702/7157/5719/5704/6233/5716/7311/10383/5347/5694/5693/5721/5696/5691/7314 62 African_swine_fever_virus R-HSA-1234174 Cellular response to hypoxia 61/1415 75/10654 8.994709729963715e-41 1.1665587823248859e-39 4.93694594201016e-40 5718/5689/5684/5720/5682/112399/5700/122706/7321/5707/84962/7422/5690/5717/9491/23198/3091/143471/5706/5705/10197/7323/7316/10213/5709/9978/5695/5714/9861/7322/5715/5711/5701/5688/1387/5687/5685/5683/5698/5708/5692/5686/5713/2033/5699/5710/5702/8453/5719/5704/6233/5716/7311/55662/5694/405/5693/5721/5696/5691/7314 61 African_swine_fever_virus R-HSA-8941858 Regulation of RUNX3 expression and activity 51/1415 55/10654 1.7375649850339352e-40 2.2307526222001332e-39 9.44067737748369e-40 5718/5689/5684/5720/5682/1029/5700/5707/5690/5717/9491/5706/5705/10197/7316/10213/5709/865/5695/5714/6714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/2033/5699/5710/5702/5719/5704/6233/5716/7311/7040/5694/5693/5721/5696/5691/7314/4193 51 African_swine_fever_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 65/1415 85/10654 2.6837157800757807e-40 3.3441203494865854e-39 1.4152515620420269e-39 8454/1147/3725/8945/1326/5601/351/9252/81793/4790/6283/6885/5606/5604/5594/4214/6500/28512/51295/23118/8517/4615/7100/5528/7316/79155/7335/5970/4792/9261/4793/177/3146/7867/5519/64127/1432/23291/5602/3656/10454/6288/3654/7189/6285/5609/6233/1385/2353/7311/5518/1386/5599/5600/7334/3551/6416/5608/4791/7314/28511/5595/5515/257397/5516 65 African_swine_fever_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 65/1415 85/10654 2.6837157800757807e-40 3.3441203494865854e-39 1.4152515620420269e-39 8454/1147/3725/8945/1326/5601/351/9252/81793/4790/6283/6885/5606/5604/5594/4214/6500/28512/51295/23118/8517/4615/7100/5528/7316/79155/7335/5970/4792/9261/4793/177/3146/7867/5519/64127/1432/23291/5602/3656/10454/6288/3654/7189/6285/5609/6233/1385/2353/7311/5518/1386/5599/5600/7334/3551/6416/5608/4791/7314/28511/5595/5515/257397/5516 65 African_swine_fever_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 65/1415 85/10654 2.6837157800757807e-40 3.3441203494865854e-39 1.4152515620420269e-39 8454/1147/3725/8945/1326/5601/351/9252/81793/4790/6283/6885/5606/5604/5594/4214/6500/28512/51295/23118/8517/4615/7100/5528/7316/79155/7335/5970/4792/9261/4793/177/3146/7867/5519/64127/1432/23291/5602/3656/10454/6288/3654/7189/6285/5609/6233/1385/2353/7311/5518/1386/5599/5600/7334/3551/6416/5608/4791/7314/28511/5595/5515/257397/5516 65 African_swine_fever_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 69/1415 95/10654 3.383568529486936e-40 4.135111154786438e-39 1.750003561303466e-39 8454/1147/3725/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/11213/5594/4214/6500/28512/51295/23118/10333/7099/8517/4615/5528/7316/79155/7335/5970/4792/7096/9261/4793/177/8651/3146/7867/5519/64127/1432/23291/5602/3656/10454/6288/3654/7189/6285/5609/6233/1385/2353/7311/5518/1386/5599/5600/7334/7097/3551/6416/5608/4791/7314/28511/5595/5515/257397/5516 69 African_swine_fever_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 69/1415 95/10654 3.383568529486936e-40 4.135111154786438e-39 1.750003561303466e-39 8454/1147/3725/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/11213/5594/4214/6500/28512/51295/23118/10333/7099/8517/4615/5528/7316/79155/7335/5970/4792/7096/9261/4793/177/8651/3146/7867/5519/64127/1432/23291/5602/3656/10454/6288/3654/7189/6285/5609/6233/1385/2353/7311/5518/1386/5599/5600/7334/7097/3551/6416/5608/4791/7314/28511/5595/5515/257397/5516 69 African_swine_fever_virus R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 48/1415 50/10654 3.823851489959192e-40 4.628681184512508e-39 1.9588853246808493e-39 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 48 African_swine_fever_virus R-HSA-202403 TCR signaling 78/1415 119/10654 3.8638268233989365e-040 4.632947068434008e-39 1.9606906720524892e-39 5295/8454/1147/5718/5689/5170/8945/5684/5290/5720/4790/6885/5682/5700/122706/7321/5707/84433/5690/5717/9491/23198/6500/23118/10892/143471/5706/5705/5788/10197/8517/7316/10213/5709/5695/7335/5970/4792/8915/5714/9861/7322/5715/5711/5795/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5728/5699/5710/5702/5719/7189/5704/6233/7454/5716/7311/3932/7334/5694/3551/5058/5693/5721/5696/997/5691/7314 78 African_swine_fever_virus R-HSA-1257604 PIP3 activates AKT signaling 122/1415 264/10654 6.033962460969777e-40 7.112533455407941e-39 3.01006633460057e-39 5295/1147/5718/2308/5689/5170/27161/3725/5684/8841/5290/5720/5682/90865/5468/5525/1459/842/5700/122706/5707/2146/8870/5526/10273/207/6045/5690/5594/2069/5717/1027/9491/23198/930/3082/941/143471/5706/2064/57761/5705/10197/4615/5528/7316/10213/5709/1950/5695/1457/1026/5714/6714/2099/9861/10014/5715/5519/5711/1958/2932/5701/5688/5687/2247/5685/29851/5683/5698/5708/5880/5692/5686/5713/2534/23512/5728/5699/6009/5529/5710/6615/3630/5702/3066/3065/7157/23028/942/5719/3654/7189/5371/23112/5704/6233/5527/2475/5716/1385/7311/3932/5518/1386/1956/331/5694/26523/7874/5693/5721/5696/5691/940/7314/5879/5595/4193/5515/3556/5516 122 African_swine_fever_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 68/1415 93/10654 6.099654969626008e-40 7.112533455407941e-39 3.01006633460057e-39 54106/8454/1147/3665/3725/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/5594/4214/6500/28512/51295/23118/7099/8517/4615/5528/7316/79155/7335/5970/4792/9261/4793/177/3146/7867/5519/64127/1432/23291/5602/3656/10454/6288/3654/7189/6285/5609/6233/51311/1385/2353/7311/5518/1386/5599/5600/7334/3551/6416/5608/4791/51284/7314/28511/5595/5515/257397/5516 68 African_swine_fever_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 68/1415 93/10654 6.099654969626008e-40 7.112533455407941e-39 3.01006633460057e-39 54106/8454/1147/3665/3725/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/5594/4214/6500/28512/51295/23118/7099/8517/4615/5528/7316/79155/7335/5970/4792/9261/4793/177/3146/7867/5519/64127/1432/23291/5602/3656/10454/6288/3654/7189/6285/5609/6233/51311/1385/2353/7311/5518/1386/5599/5600/7334/3551/6416/5608/4791/51284/7314/28511/5595/5515/257397/5516 68 African_swine_fever_virus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 95/1415 171/10654 8.331555051113059e-40 9.626733154513361e-39 4.07409055609452e-39 10921/6158/5718/5689/6138/5684/9349/4736/5720/6206/6194/6191/6128/5682/6129/5700/122706/5707/6222/6176/5690/6136/6125/5717/9491/23198/6224/6146/51065/6154/26986/143471/6202/5706/5705/3670/10197/6232/6164/7316/6155/10213/5709/9978/6218/5695/5714/6229/6231/9861/6130/5715/5711/6204/5701/5688/6228/23521/5687/5685/1605/5683/5698/5708/5692/5686/5713/5699/6235/5710/6181/6124/5702/8453/6207/5719/6139/5704/6233/5716/7311/6223/6188/6135/5694/5693/5721/6137/5696/6170/5691/6122/6133/7314/6230 95 African_swine_fever_virus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 56/1415 66/10654 1.678353680803668e-39 1.921790566037353e-38 8.133131634809619e-39 5718/5689/5684/5720/5682/112399/5700/122706/7321/5707/84962/5690/5717/9491/23198/3091/143471/5706/5705/10197/7323/7316/10213/5709/9978/5695/5714/9861/7322/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8453/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 56 African_swine_fever_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 67/1415 92/10654 3.4975219427927116e-39 3.9690628475799434e-38 1.679730933051763e-38 54106/8454/1147/3725/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/5594/4214/6500/28512/51295/23118/7099/8517/4615/5528/7316/79155/7335/5970/4792/9261/4793/177/3146/7867/5519/64127/1432/23291/5602/3656/10454/6288/3654/7189/6285/5609/6233/51311/1385/2353/7311/5518/1386/5599/5600/7334/3551/6416/5608/4791/51284/7314/28511/5595/5515/257397/5516 67 African_swine_fever_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 69/1415 98/10654 9.417207444872378e-39 1.0499360230204204e-37 4.443391509076441e-38 8454/1147/3725/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/11213/5594/4214/6500/28512/51295/23118/10333/7099/8517/4615/5528/7316/79155/7335/5970/4792/7096/9261/4793/177/8651/3146/7867/5519/64127/1432/23291/5602/3656/10454/6288/3654/7189/6285/5609/6233/1385/2353/7311/5518/1386/5599/5600/7334/7097/3551/6416/5608/4791/7314/28511/5595/5515/257397/5516 69 African_swine_fever_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 69/1415 98/10654 9.417207444872378e-39 1.0499360230204204e-37 4.443391509076441e-38 8454/1147/3725/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/11213/5594/4214/6500/28512/51295/23118/10333/7099/8517/4615/5528/7316/79155/7335/5970/4792/7096/9261/4793/177/8651/3146/7867/5519/64127/1432/23291/5602/3656/10454/6288/3654/7189/6285/5609/6233/1385/2353/7311/5518/1386/5599/5600/7334/7097/3551/6416/5608/4791/7314/28511/5595/5515/257397/5516 69 African_swine_fever_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 68/1415 97/10654 5.201657764794264e-38 5.748962625263922e-37 2.4329950735101777e-037 54106/8454/1147/3665/3725/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/5594/4214/6500/28512/51295/23118/7099/8517/4615/5528/7316/79155/7335/5970/4792/9261/4793/177/3146/7867/5519/64127/1432/23291/5602/3656/10454/6288/3654/7189/6285/5609/6233/51311/1385/2353/7311/5518/1386/5599/5600/7334/3551/6416/5608/4791/51284/7314/28511/5595/5515/257397/5516 68 African_swine_fever_virus R-HSA-180585 Vif-mediated degradation of APOBEC3G 49/1415 54/10654 8.488128832067176e-38 9.300354953066708e-37 3.9359653658678106e-37 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 49 African_swine_fever_virus R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 50/1415 56/10654 9.8096807496932e-38 1.0656499344324835e-36 4.509893713984009e-37 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 50 African_swine_fever_virus R-HSA-8878159 Transcriptional regulation by RUNX3 67/1415 96/10654 2.858954473281094e-37 3.0794331657120936e-36 1.3032343763127914e-36 7004/5718/5689/5684/5720/5682/1499/2648/1029/5700/5707/5690/5717/9491/5706/5705/10197/7316/10213/5709/865/5695/1026/5714/6714/4609/9861/4089/5715/22938/8850/5711/5701/5688/1387/5687/4088/5685/5683/5698/5708/5692/5686/5713/2033/595/5699/5710/5702/7157/861/5719/5704/6233/5716/7311/7040/3845/5694/4851/5693/5721/5696/5691/3676/7314/4193 67 African_swine_fever_virus R-HSA-5617833 Cilium Assembly 101/1415 201/10654 3.8312886799342665e-37 4.092073875795338e-36 1.7317899296297307e-36 115106/22995/55559/79867/11258/22981/8636/7531/54903/10142/80776/11190/203068/54801/7532/10575/55125/1454/10382/85302/51134/95681/121441/7277/79441/10013/5116/54806/9814/91147/5048/1781/23354/80321/8766/22832/146057/8655/9738/79598/983/55722/4957/10121/9702/5566/79959/132320/347240/84131/6950/7846/7840/7283/3320/8729/22919/10376/27077/22994/11064/4867/79600/10540/84902/10733/1069/4751/117177/5577/80254/57545/26005/54930/5518/26123/10383/55835/54820/5347/23322/22948/9662/55142/80184/23332/1453/22897/9793/4218/5108/261734/8481/57787/140735/93323/10806/51259/55755/9657/1778 101 African_swine_fever_virus R-HSA-169911 Regulation of Apoptosis 48/1415 53/10654 5.97488598509262e-37 6.328400072543933e-36 2.6782164371774813e-36 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 48 African_swine_fever_virus R-HSA-5663202 Diseases of signal transduction 146/1415 377/10654 1.0463794476769876e-36 1.0991308082623564e-35 4.651586757398353e-36 5295/8454/4000/1147/5718/2308/5689/5170/5684/4893/8841/5290/5720/142678/5682/5604/1499/2648/5525/892/10142/842/5700/122706/5707/5430/5526/207/5690/5594/2069/9530/5717/1027/9491/23198/6500/409/930/3082/941/10013/143471/5706/2064/5705/23164/10197/5528/7316/10213/5709/9978/1950/5695/6774/9612/1026/1024/5714/6772/6714/2099/5605/4609/7415/9861/4089/10014/5715/2962/22938/5519/8850/5711/2932/5701/5688/1387/5687/3717/4088/2247/5685/6907/29851/5683/5698/5708/5880/3320/5692/5686/5713/2335/2534/2033/3690/55294/5728/5699/5529/5710/11064/5702/3066/3065/5894/942/5719/6868/5704/6233/5527/2475/5716/1385/7311/3932/5518/6469/1956/11160/60/7040/808/3845/5694/3265/801/4851/5693/5721/5696/11140/5691/5245/940/7314/1523/5879/5595/4193/805/5515/5516 146 African_swine_fever_virus R-HSA-75893 TNF signaling 42/1415 43/10654 3.305926512235194e-36 3.4441250795499435e-35 1.4575741568181053e-35 7124/1147/25999/90268/81858/84888/7186/56957/6885/56928/8737/55072/7375/9530/330/23118/841/27005/8517/8887/7316/8439/7128/7132/329/9099/10616/10454/55512/8567/6868/6233/7311/6610/8772/331/8717/1540/3551/7185/7314/257397 42 African_swine_fever_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 63/1415 88/10654 3.606119830501594e-36 3.726323824851647e-35 1.5770023392266278e-35 5718/3303/5689/5684/5720/5682/5700/122706/5707/207/5690/5578/3184/5717/9491/3315/23198/26986/143471/5706/5705/10197/7538/7316/10213/5709/5695/9261/5714/9861/5715/5711/1432/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5580/5716/7514/7311/8021/5600/5694/3312/5693/5721/5696/5691/7314/1994 63 African_swine_fever_virus R-HSA-5678895 Defective CFTR causes cystic fibrosis 51/1415 61/10654 2.0449620041078003e-35 2.0960860542104953e-34 8.870760476223141e-35 5718/5689/5684/5720/5682/5700/122706/5707/79139/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/11160/5694/5693/5721/5696/5691/7314 51 African_swine_fever_virus R-HSA-5387390 Hh mutants abrogate ligand secretion 50/1415 59/10654 2.532601120544488e-35 2.575148819369635e-34 1.0898182506090387e-34 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 50 African_swine_fever_virus R-HSA-4641258 Degradation of DVL 49/1415 57/10654 2.958354874556085e-35 2.984181782191098e-34 1.2629234259800832e-34 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 49 African_swine_fever_virus R-HSA-4641257 Degradation of AXIN 48/1415 55/10654 3.2253794835106373e-35 3.2279191523952914e-34 1.3660745263770707e-34 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 48 African_swine_fever_virus R-HSA-8948751 Regulation of PTEN stability and activity 54/1415 69/10654 1.3936665711569423e-34 1.383867353078495e-33 5.8566086995164275e-34 5718/5689/5684/5720/5682/1459/5700/122706/5707/10273/207/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/1457/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5728/5699/5710/5702/5719/5704/6233/5716/7311/331/5694/5693/5721/5696/5691/7314 54 African_swine_fever_virus R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 45/1415 50/10654 2.051635851658571e-34 2.0214179592698013e-33 8.554760670726479e-34 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/5694/5693/5721/5696/5691/4360 45 African_swine_fever_virus R-HSA-9013694 Signaling by NOTCH4 59/1415 82/10654 3.862567291850784e-34 3.7764023291864205e-33 1.5981958592192315e-33 8454/5718/5689/5684/5720/5682/2648/5700/5707/207/5690/5717/9491/6500/5706/5705/10197/10460/7316/10213/5709/9978/5695/5714/9861/5715/22938/8850/5711/5701/5688/1387/5687/4088/5685/5683/5698/5708/5692/5686/5713/2033/55294/5699/5710/5702/5719/5704/6233/2324/5716/7311/5694/4851/5693/5721/5696/5691/7314 59 African_swine_fever_virus R-HSA-5658442 Regulation of RAS by GAPs 53/1415 68/10654 8.484113388154467e-34 8.231532913239944e-33 3.483633540656435e-33 5718/5689/5684/4893/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5921/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/3845/5694/3265/5693/5721/5696/5691/7314 53 African_swine_fever_virus R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 45/1415 51/10654 1.5235626292416922e-33 1.4670061377016596e-32 6.208456966048682e-33 5718/5689/5684/1728/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/5694/5693/5721/5696/5691 45 African_swine_fever_virus R-HSA-5358346 Hedgehog ligand biogenesis 51/1415 65/10654 8.062466655622174e-33 7.704808360372769e-32 3.260720586484314e-32 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/6868/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 51 African_swine_fever_virus R-HSA-1852241 Organelle biogenesis and maintenance 120/1415 296/10654 1.8792113527977276e-32 1.782445992093964e-31 7.543417134953958e-32 115106/22995/55559/79867/8841/11258/22981/8636/7531/54903/10142/80776/11190/203068/54801/7532/10575/55125/1454/10382/85302/23408/51134/95681/121441/7277/79441/10013/5116/54806/5465/9814/91147/5048/1781/23354/80321/8766/22832/146057/8655/9738/79598/983/55722/4957/10121/9702/5566/79959/132320/347240/84131/1432/5571/1387/6950/7846/7840/6907/7283/3320/8729/22919/10376/27077/22994/11064/4867/79600/10540/84902/10733/6648/1069/6256/4751/117177/10498/5577/80254/1385/57545/26005/54930/23054/5518/26123/10383/1386/55835/54820/5347/23322/22948/6742/808/5600/9662/55142/80184/23332/1453/22897/801/9793/4218/5108/261734/8481/57787/140735/93323/10806/51259/55755/9657/10891/805/1778 120 African_swine_fever_virus R-HSA-168254 Influenza Infection 82/1415 155/10654 2.1177103907288174e-32 1.993785116012094e-31 8.437816839473105e-32 3839/6158/23165/3303/6138/3837/3838/5903/9349/4736/6206/6194/402569/6191/55706/7175/6128/9631/6129/5430/6222/6176/6136/6125/6224/6146/51065/6154/348995/6202/79023/57122/23636/6232/10762/23511/6164/6155/6218/53371/23279/4927/6229/6231/9688/79902/6130/2962/3840/6204/9883/6228/23521/23225/3320/6235/6181/6124/5901/6207/8086/3836/6139/6233/7514/7311/6223/9972/1213/6188/8021/7040/6396/6135/129401/55746/6137/6170/8480/6122/6133/6230 82 African_swine_fever_virus R-HSA-3700989 Transcriptional Regulation by TP53 136/1415 365/10654 4.019572530330631e-32 3.7565269750369354e-31 1.5897844914852576e-31 1017/6875/834/6118/2176/5170/27161/3725/9134/8621/902/9156/1763/7531/1029/7027/1459/79370/5430/7532/207/10971/22974/9212/835/6878/1027/4869/898/355/7295/7533/2810/55367/545/472/117584/79813/332/580/7001/5934/7316/1869/891/6872/890/2539/1457/54971/4331/10769/983/1026/6790/641/5933/5111/8797/4194/2962/5519/1647/1432/5571/10524/10848/1387/8812/1616/9099/28984/5985/51755/2033/995/1874/5728/6009/8738/905/2068/1111/3066/3065/7157/55215/8900/5984/8626/5371/23112/10498/6233/5527/2475/672/1025/5932/2353/7311/7161/5518/1386/55835/6880/6908/10419/4513/5300/5983/6117/50484/5600/7159/904/4697/3276/144455/79733/29883/26523/7874/6882/5052/637/1020/2744/5608/1022/7248/10919/7314/4193/5515/5516 136 African_swine_fever_virus R-HSA-5683057 MAPK family signaling cascades 119/1415 294/10654 4.155990080084802e-32 3.8556667093341485e-31 1.6317410149238065e-31 5923/5718/2308/5689/27161/3725/5684/3562/4893/5720/1437/5682/5604/5525/5700/10642/122706/5707/5567/5526/5690/7010/5594/2069/5568/5717/9491/3315/23198/409/3082/143471/5706/2064/5921/5705/10197/5528/7316/10213/5709/9978/1950/5695/983/5597/3718/5714/6714/5605/4609/9861/5566/5715/5519/5711/5701/5688/3567/5687/3558/3717/2247/5685/5683/5698/5708/5692/5686/5713/2335/2534/3690/5699/5529/5710/8555/5702/998/5894/8556/896/5719/3563/23112/5704/6233/5527/3716/5716/7514/7311/5518/1956/60/1843/808/3845/5694/3265/3559/26523/5058/801/7297/8202/3569/5693/5721/5696/5691/5245/7314/5879/5595/805/5515/284/5516 119 African_swine_fever_virus R-HSA-6807070 PTEN Regulation 77/1415 140/10654 5.089321229839802e-32 4.687338610961152e-31 1.983709495383783e-31 5718/5689/27161/3725/5684/8841/5720/5682/5468/1459/5700/122706/5707/2146/10273/207/6045/5690/5594/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/1457/5714/9861/10014/5715/5711/1958/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/23512/5728/5699/6009/5710/6615/5702/3066/3065/7157/23028/5719/5371/23112/5704/6233/2475/5716/7311/1386/331/5694/26523/7874/5693/5721/5696/5691/7314/5595 77 African_swine_fever_virus R-HSA-5610787 Hedgehog 'off' state 68/1415 113/10654 1.0399715468773492e-31 9.509380115691446e-31 4.024426054178913e-31 8454/5718/5689/8945/5684/5720/2735/5682/54903/5700/122706/5707/5567/5690/10382/5568/5717/9491/23198/6500/7277/143471/5706/5705/10197/7316/10213/5709/9978/5695/5727/5714/9861/5566/5715/5711/2932/5701/5688/5687/7846/5576/5685/5683/5698/5708/5692/5686/5713/10376/5699/5710/5702/5719/5577/5704/6233/5716/7311/10383/23322/5694/8481/5693/5721/5696/5691/7314 68 African_swine_fever_virus R-HSA-1236974 ER-Phagosome pathway 57/1415 83/10654 2.8536879917177076e-31 2.590741026766576e-30 1.0964169652389088e-30 1147/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10333/10197/7099/8517/4615/7316/10213/5709/5695/29927/7096/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/7097/3551/5693/5721/5696/5691/7314 57 African_swine_fever_virus R-HSA-5688426 Deubiquitination 118/1415 297/10654 6.097525495000989e-31 5.4964219178342246e-30 2.3261183485968687e-30 5718/5689/10600/5684/5720/23326/7186/56957/6885/5682/90865/2648/5700/122706/7321/5707/991/8737/84196/7375/5690/9817/57506/51720/5717/9491/23198/63967/409/330/3091/143471/5706/5705/4287/27005/10197/7706/8517/580/7416/7316/10213/5709/993/5695/79155/890/7417/80124/4792/9738/983/5714/8678/2099/4609/7415/9861/4194/23586/4089/5715/64127/8850/7128/5711/5701/5688/9097/329/5687/6502/9099/4088/5685/5683/5698/5708/5692/5686/5713/2033/64135/5728/5699/5710/10454/8473/5702/7157/8900/10869/63891/5719/7189/5704/6233/5716/672/7311/84282/367/114548/7187/10318/60/7040/7345/1540/5694/7874/5693/5721/5696/5691/7314/4193 118 African_swine_fever_virus R-HSA-168255 Influenza Life Cycle 77/1415 144/10654 6.673556958076558e-31 5.973303446278383e-30 2.527937439271402e-30 6158/23165/3303/6138/3837/5903/9349/4736/6206/6194/6191/55706/7175/6128/9631/6129/5430/6222/6176/6136/6125/6224/6146/51065/6154/348995/6202/79023/57122/23636/6232/10762/23511/6164/6155/6218/53371/23279/4927/6229/6231/9688/79902/6130/2962/6204/9883/6228/23521/23225/3320/6235/6181/6124/5901/6207/8086/3836/6139/6233/7514/7311/6223/9972/1213/6188/8021/6396/6135/129401/55746/6137/6170/8480/6122/6133/6230 77 African_swine_fever_virus R-HSA-5619084 ABC transporter disorders 54/1415 77/10654 2.0334143516720278e-30 1.807321427255348e-29 7.6486914516334665e-030 5718/5689/5684/5720/5682/5700/122706/5707/79139/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/19/335/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/11160/5694/5693/5721/5696/10058/5691/7314 54 African_swine_fever_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 65/1415 108/10654 2.3080961855456167e-30 2.037215452658666e-29 8.621616599516156e-30 5295/3605/7124/2308/1052/7291/596/7412/3593/207/246/5451/3684/9021/7422/3553/3082/5743/3091/4318/4312/3383/301/6657/6778/3576/332/3662/4313/3565/6774/4314/1026/3718/7133/3606/6772/8651/4609/149233/3552/3717/598/2247/3320/4843/2335/595/6288/7157/3716/2353/6347/240/7040/3687/51561/6356/3312/7297/3569/3162/4170/3586/3596 65 African_swine_fever_virus R-HSA-351202 Metabolism of polyamines 46/1415 59/10654 1.7181033909131884e-29 1.506006489552181e-28 6.373508767743298e-29 5718/5689/5684/1728/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/6303/5694/5693/5721/5696/5691 46 African_swine_fever_virus R-HSA-450294 MAP kinase activation 48/1415 64/10654 2.3034903021848414e-29 1.9916572612768256e-28 8.428811632054808e-29 8454/1147/3725/8945/1326/5601/9252/4790/6885/5606/5604/5594/6500/23118/8517/5528/7316/79155/7335/9261/7867/5519/64127/1432/23291/5602/3656/10454/3654/7189/5609/6233/1385/2353/7311/5518/1386/5599/5600/7334/3551/6416/5608/7314/5595/5515/257397/5516 48 African_swine_fever_virus R-HSA-4608870 Asymmetric localization of PCP proteins 48/1415 64/10654 2.3034903021848414e-29 1.9916572612768256e-28 8.428811632054808e-29 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 48 African_swine_fever_virus R-HSA-4086400 PCP/CE pathway 58/1415 92/10654 9.249782142207147e-29 7.943562907260327e-28 3.3617629265062957e-28 5718/5689/5684/5720/5579/5682/5700/122706/5707/5690/5578/5717/9491/23198/409/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5881/5711/5701/5688/5687/5685/5683/5698/5708/5880/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/163/7311/1213/5694/1175/5693/5721/5696/6259/5691/7314/5879 58 African_swine_fever_virus R-HSA-1236975 Antigen processing-Cross presentation 60/1415 99/10654 2.379264868230526e-28 2.0295608372624153e-27 8.589221813251846e-28 1147/5718/5689/5684/5720/653361/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10333/10197/7099/8517/4615/7316/10213/5709/5695/29927/7096/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/4012/5716/7311/5694/7097/3551/5693/5721/5696/5691/7314/4360 60 African_swine_fever_virus R-HSA-168273 Influenza Viral RNA Transcription and Replication 71/1415 134/10654 3.0221565072021296e-28 2.560773947102604e-27 1.0837347194247637e-27 6158/23165/6138/5903/9349/4736/6206/6194/6191/55706/7175/6128/9631/6129/5430/6222/6176/6136/6125/6224/6146/51065/6154/348995/6202/79023/57122/23636/6232/10762/23511/6164/6155/6218/53371/23279/4927/6229/6231/9688/79902/6130/2962/6204/9883/6228/23521/23225/3320/6235/6181/6124/6207/8086/6139/6233/7311/6223/9972/6188/8021/6396/6135/129401/55746/6137/6170/8480/6122/6133/6230 71 African_swine_fever_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 84/1415 182/10654 1.127941549347655e-27 9.49413052464152e-27 4.017972336818764e-27 23165/7020/5905/6670/5903/55706/7175/55143/5241/9631/5468/1029/6045/9212/3619/4869/7153/10274/348995/79023/57122/23636/10735/8517/332/10762/5465/5885/23511/53371/1655/5970/4792/9612/6790/641/5111/2099/23279/4927/9688/79902/9883/7341/1387/10401/10521/1616/1789/23225/2908/2033/23512/8243/9126/142/3066/3065/7157/1069/6256/8086/7329/5371/672/115426/7158/367/9972/6612/7155/8021/9641/6117/6294/6396/129401/55746/7421/4791/8480/10891/10062/4193 84 African_swine_fever_virus R-HSA-5357905 Regulation of TNFR1 signaling 32/1415 33/10654 1.8644944308878495e-27 1.559060803722669e-26 6.598037771355202e-27 7124/1147/25999/90268/81858/84888/7186/56957/56928/8737/55072/7375/330/841/27005/8517/8887/7316/7128/7132/329/9099/10616/8567/6233/7311/331/8717/1540/3551/7185/7314 32 African_swine_fever_virus R-HSA-4615885 SUMOylation of DNA replication proteins 38/1415 45/10654 5.500046864373801e-27 4.568993179489609e-26 1.9336250070141127e-26 23165/5905/5903/55706/7175/55143/9631/9212/3619/7153/348995/79023/57122/23636/332/10762/23511/53371/6790/5111/23279/4927/9688/79902/9883/7341/10401/23225/8086/7329/9972/6612/7155/8021/6396/129401/55746/8480 38 African_swine_fever_virus R-HSA-5689880 Ub-specific processing proteases 93/1415 220/10654 6.039991053797831e-27 4.9849536554396387e-26 2.109661947020295e-26 5718/5689/10600/5684/5720/23326/7186/6885/5682/90865/2648/5700/122706/5707/991/8737/84196/7375/5690/9817/5717/9491/23198/63967/409/330/3091/143471/5706/5705/27005/10197/8517/7416/7316/10213/5709/993/5695/890/7417/4792/9738/5714/8678/4609/9861/4194/23586/4089/5715/5711/5701/5688/9097/329/5687/6502/9099/4088/5685/5683/5698/5708/5692/5686/5713/64135/5728/5699/5710/10454/5702/7157/8900/10869/63891/5719/7189/5704/6233/5716/7311/367/1540/5694/7874/5693/5721/5696/5691/7314/4193 93 African_swine_fever_virus R-HSA-448424 Interleukin-17 signaling 49/1415 72/10654 9.20089306346693e-27 7.544732312042882e-26 3.192975453603804e-26 8454/3605/1147/3725/8945/1326/5601/9252/4790/6885/5606/5604/5594/6500/23118/8517/5528/7316/79155/7335/9261/7867/5519/64127/1432/23291/5602/3656/10454/3654/7189/5609/6233/1385/2353/7311/5518/1386/5599/5600/7334/3551/6416/5608/7314/5595/5515/257397/5516 49 African_swine_fever_virus R-HSA-3371556 Cellular response to heat stress 55/1415 89/10654 1.0730308356197698e-26 8.74244994918415e-26 3.6998566599305155e-26 23165/3303/6118/6782/5903/55706/7175/9631/7531/1915/5594/9530/3308/10049/348995/10013/545/79023/472/57122/23636/10762/23511/3305/53371/9261/23279/4927/9688/7415/79902/9883/2932/1387/259217/23225/3310/3309/3320/2033/9531/8086/2475/3306/9972/23411/8021/6117/6396/129401/3312/55746/8480/10728/5595 55 African_swine_fever_virus R-HSA-194315 Signaling by Rho GTPases 146/1415 455/10654 1.8686606982672306e-26 1.5127820047755733e-25 6.402183149946731e-26 220134/5170/5905/55839/11130/25/79682/5590/5903/10403/54908/6249/55143/653361/5579/1499/55055/25936/5525/9735/7531/80776/1783/1058/991/401541/79019/5526/4627/7532/10928/10971/348235/80152/4771/10382/5578/9212/5594/1063/6722/29127/8379/1027/3619/10627/1894/79172/7533/2810/147841/7277/348995/23421/55920/79023/57122/79980/64105/89839/6232/332/1780/23122/5528/5048/1781/5501/9824/57405/8655/4085/5585/6714/23279/55166/79902/3796/54821/5881/5519/9183/1432/81565/4637/2491/1062/699/7846/999/5880/22919/79784/9475/1060/91687/995/79003/10376/5529/51143/998/23028/10788/83540/11004/5527/5580/7454/701/9055/7514/6093/9184/57120/9928/367/5518/10383/54820/5347/57551/60/5300/84643/808/6396/5600/23332/25909/5058/801/64946/9793/10726/81930/55746/140735/5500/5879/4221/5595/805/5515/1778/5516 146 African_swine_fever_virus R-HSA-2990846 SUMOylation 84/1415 188/10654 1.8832838422637055e-26 1.5149707364032719e-25 6.411445991983701e-26 23165/7020/5905/6670/5903/55706/7175/55143/5241/9631/5468/1029/6045/9212/3619/4869/7153/10274/348995/79023/57122/23636/10735/8517/332/10762/5465/5885/23511/53371/1655/5970/4792/9612/6790/641/5111/2099/23279/4927/9688/79902/9883/7341/1387/10401/10521/1616/1789/23225/2908/2033/23512/8243/9126/142/3066/3065/7157/1069/6256/8086/7329/5371/672/115426/7158/367/9972/6612/7155/8021/9641/6117/6294/6396/129401/55746/7421/4791/8480/10891/10062/4193 84 African_swine_fever_virus R-HSA-5632684 Hedgehog 'on' state 53/1415 85/10654 4.832411062817757e-26 3.8628895980134397e-25 1.6347977842435444e-25 5718/5689/5684/5720/2735/5682/5700/122706/5707/5690/5717/9491/23198/409/143471/5706/5705/10197/7316/10213/5709/9978/5695/5727/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 53 African_swine_fever_virus R-HSA-5619115 Disorders of transmembrane transporters 80/1415 176/10654 7.469383093094319e-26 5.9334911945768e-25 2.5110886582705244e-25 5718/23165/5689/5684/5903/5720/55706/7175/5682/9631/5700/122706/5707/79139/5690/5717/9491/23198/348995/143471/79023/5706/57122/5705/23636/10197/10762/23511/7316/10213/5709/19/335/5695/53371/5714/23279/4927/9688/7415/9861/79902/5715/5711/9883/5701/5688/5687/23225/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8086/5719/5704/6233/5716/7311/9972/11160/8021/6396/129401/213/5694/55746/5693/5721/5696/10058/5691/8480/7314 80 African_swine_fever_virus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 47/1415 69/10654 9.566078734041261e-26 7.551854702463629e-25 3.195989691464586e-25 23165/3303/6118/6782/5903/55706/7175/9631/7531/5594/9530/3308/10049/348995/545/79023/472/57122/23636/10762/23511/3305/53371/9261/23279/4927/9688/79902/9883/2932/259217/23225/3310/3309/9531/8086/3306/9972/23411/8021/6117/6396/129401/3312/55746/8480/5595 47 African_swine_fever_virus R-HSA-8878171 Transcriptional regulation by RUNX1 96/1415 239/10654 9.735939377195225e-26 7.638505523713044e-25 3.2326608328438987e-25 55904/5718/6595/5689/27161/25/894/5684/3562/5720/902/2624/1437/5579/6597/5682/1459/5700/122706/5707/6045/9021/5690/5717/9491/23198/4005/143471/5706/6598/5705/10197/6599/7316/10213/5709/865/5695/7082/1457/4331/5714/6714/2099/9861/5715/8850/5711/5701/5688/1387/5687/3558/5685/5683/8289/5698/5708/5692/5686/5713/2033/1021/6605/6602/595/50943/5699/5710/3458/5702/3065/861/896/5719/5371/23112/5704/6233/5716/7311/6688/7161/860/3276/5694/6601/3559/26523/1022/1493/5693/5721/5696/5691/7314 96 African_swine_fever_virus R-HSA-157118 Signaling by NOTCH 95/1415 235/10654 9.93769257789543e-26 7.748961513193308e-25 3.2794064625796353e-25 8454/5718/1999/5689/27161/3725/5684/8841/5720/142678/5682/5584/2648/892/7027/5700/5707/207/5690/5717/9491/6500/409/3091/51548/10013/5706/5705/10197/10460/488/7316/10213/5709/9978/1950/1869/4854/5695/9612/1024/5714/6772/4609/9861/10014/5715/22938/8850/5711/5701/5688/1387/5687/4088/5685/6907/5683/5698/5708/5692/5686/5713/2033/595/55294/5699/5710/3002/5702/3066/3065/7157/7088/861/5719/6868/2683/23112/5704/6233/2324/5716/1385/7311/1956/9787/5694/26523/4851/5693/5721/5696/5691/7314 95 African_swine_fever_virus R-HSA-5358351 Signaling by Hedgehog 72/1415 149/10654 2.1292326122196627e-25 1.6484417512208768e-24 6.97630324132567e-25 8454/5718/5689/8945/5684/5720/2735/5682/54903/5700/122706/5707/5567/5690/10382/5568/5717/9491/23198/6500/409/7277/143471/5706/5705/10197/7316/10213/5709/9978/5695/5727/5714/7415/9861/5566/5715/5711/2932/5701/5688/5687/7846/5576/5685/5683/5698/5708/5692/5686/5713/10376/5699/5710/5702/5719/6868/5577/5704/6233/5716/7311/10383/6469/23322/5694/8481/5693/5721/5696/5691/7314 72 African_swine_fever_virus R-HSA-2980766 Nuclear Envelope Breakdown 40/1415 52/10654 2.1399912584692735e-25 1.6484417512208768e-24 6.97630324132567e-25 4000/23165/5903/55706/7175/5579/9631/91754/5578/140609/348995/79023/9133/57122/23636/7443/10762/23511/891/53371/983/23279/4927/9688/79902/9883/23225/8815/9663/8086/64900/4001/23175/9972/5347/8021/6396/129401/55746/8480 40 African_swine_fever_virus R-HSA-5684996 MAPK1/MAPK3 signaling 99/1415 255/10654 3.7463618685982614e-25 2.8684493584267412e-24 1.213944777966843e-24 5923/5718/5689/5684/3562/4893/5720/1437/5682/5604/5525/5700/122706/5707/5526/5690/7010/5594/2069/5717/9491/23198/409/3082/143471/5706/2064/5921/5705/10197/5528/7316/10213/5709/9978/1950/5695/983/3718/5714/6714/5605/9861/5715/5519/5711/5701/5688/3567/5687/3558/3717/2247/5685/5683/5698/5708/5692/5686/5713/2335/2534/3690/5699/5529/5710/5702/5894/5719/3563/5704/6233/5527/3716/5716/7311/5518/1956/60/1843/808/3845/5694/3265/3559/801/7297/3569/5693/5721/5696/5691/5245/7314/5595/805/5515/284/5516 99 African_swine_fever_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 29/1415 30/10654 7.651764517763329e-25 5.823588444357599e-24 2.4645771626706976e-24 7124/1147/81858/7186/56957/6885/8737/55072/7375/330/23118/27005/8517/7316/7128/7132/329/9099/10616/10454/6233/7311/331/8717/1540/3551/7185/7314/257397 29 African_swine_fever_virus R-HSA-69231 Cyclin D associated events in G1 36/1415 44/10654 1.1135335555447997e-24 8.374563012410891e-24 3.5441647267729226e-24 8454/25/894/1019/902/1029/7027/1027/6500/5925/5934/7316/1869/1875/4331/1026/5933/6714/5519/4067/3717/6502/1021/1874/595/5520/896/6233/7311/5518/1163/1022/1028/7314/5515/5516 36 African_swine_fever_virus R-HSA-69236 G1 Phase 36/1415 44/10654 1.1135335555447997e-24 8.374563012410891e-24 3.5441647267729226e-24 8454/25/894/1019/902/1029/7027/1027/6500/5925/5934/7316/1869/1875/4331/1026/5933/6714/5519/4067/3717/6502/1021/1874/595/5520/896/6233/7311/5518/1163/1022/1028/7314/5515/5516 36 African_swine_fever_virus R-HSA-9607240 FLT3 Signaling 101/1415 267/10654 1.318410932764738e-24 9.857060562023423e-24 4.171566480760255e-24 5295/54106/5923/5718/5689/5170/5684/3562/4893/5290/5720/1437/5682/5604/5525/5700/122706/5707/5526/5690/7010/5594/2069/5717/9491/23198/409/3082/143471/5706/2064/57761/5921/5705/10197/5528/7316/10213/5709/9978/1950/5695/3718/5714/6714/5605/9861/5715/5519/5711/5701/5688/3567/5687/3558/3717/2247/5685/5683/5698/5708/5692/5686/5713/2335/2534/3690/5699/5529/5710/5702/5894/5719/3563/5704/6233/5527/3716/5716/7311/5518/1956/60/1843/808/3845/5694/3265/3559/801/5693/5721/5696/5691/5245/7314/5595/805/5515/284/5516 101 African_swine_fever_virus R-HSA-5673001 RAF/MAP kinase cascade 96/1415 249/10654 3.753538660105008e-24 2.789910898826588e-23 1.1807068361426034e-23 5923/5718/5689/5684/3562/4893/5720/1437/5682/5604/5525/5700/122706/5707/5526/5690/7010/5594/2069/5717/9491/23198/409/3082/143471/5706/2064/5921/5705/10197/5528/7316/10213/5709/9978/1950/5695/3718/5714/6714/5605/9861/5715/5519/5711/5701/5688/3567/5687/3558/3717/2247/5685/5683/5698/5708/5692/5686/5713/2335/2534/3690/5699/5529/5710/5702/5894/5719/3563/5704/6233/5527/3716/5716/7311/5518/1956/60/1843/808/3845/5694/3265/3559/801/5693/5721/5696/5691/5245/7314/5595/805/5515/284/5516 96 African_swine_fever_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 30/1415 33/10654 1.386097915934839e-23 1.0242618902053375e-22 4.334737056564888e-23 1147/351/4790/6283/6885/28512/23118/8517/7316/7335/5970/4792/4793/177/3146/64127/3656/10454/6288/3654/7189/6285/6233/7311/7334/3551/4791/7314/28511/257397 30 African_swine_fever_virus R-HSA-1169408 ISG15 antiviral mechanism 46/1415 72/10654 2.0229859543633572e-23 1.486251530633426e-22 6.289904610159268e-23 3839/23165/3837/3838/5903/402569/55706/7175/9631/348995/79023/57122/23636/7706/10762/23511/7316/53371/6772/23279/4927/9688/79902/23586/3840/9883/23225/3661/8086/7324/3836/4599/6233/3716/7311/9972/5300/8021/6396/129401/7334/55746/5495/8480/7314/5595 46 African_swine_fever_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 48/1415 78/10654 2.44765219834595e-23 1.7879114621251163e-22 7.566547328220087e-23 1147/3665/351/7186/4790/6283/7321/8737/29110/57506/4214/28512/841/7706/8517/8887/7323/7316/5970/4792/4793/177/3146/23586/7322/7128/1387/2033/64135/6288/3661/7189/3439/6285/6233/10010/7311/84282/7187/8772/5300/9641/1540/3551/3456/4791/7314/28511 48 African_swine_fever_virus R-HSA-73887 Death Receptor Signalling 67/1415 141/10654 3.444206876072483e-23 2.5014782511360716e-22 1.0586404292770158e-22 7124/1147/25999/4804/90268/81858/84888/8841/7186/56957/4790/6885/5584/7531/56928/8737/55072/7375/835/9530/8878/1894/355/330/23421/23118/841/27005/8517/4615/8887/7316/5970/4792/8439/8797/7128/7132/329/9099/836/10616/8837/4803/10454/3066/3065/55512/8567/3654/7189/6868/6233/7311/6610/26574/8772/331/5599/8717/1540/3551/7185/8743/7314/5879/257397 67 African_swine_fever_virus R-HSA-3858494 Beta-catenin independent WNT signaling 68/1415 146/10654 6.83456329817633e-23 4.935642018171657e-22 2.0887929697177661e-22 5718/5689/27161/5684/5720/6885/5579/5682/1499/4772/5700/122706/5707/5690/5578/5717/9491/23198/409/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5881/5711/5701/5688/5687/5685/5683/5698/5708/5880/5692/5686/5713/5699/5710/5702/5719/23112/5704/6233/5716/163/7311/1213/808/3845/5694/1175/26523/801/5693/5721/5696/6259/5691/7314/5879/805 68 African_swine_fever_virus R-HSA-177243 Interactions of Rev with host cellular proteins 31/1415 36/10654 9.531667732035179e-23 6.844491348823001e-22 2.896629325643756e-22 23165/5905/3837/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/7514/9972/8021/6396/129401/1104/55746/8480 31 African_swine_fever_virus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 25/1415 25/10654 1.0016580582304918e-22 7.152288719162669e-22 3.026890997964408e-22 11065/246184/7321/991/8697/8881/7316/4085/51433/119504/51529/7324/64682/29945/10393/4751/6233/51434/701/7311/9184/25906/29882/7314/996 25 African_swine_fever_virus R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 30/1415 35/10654 6.297987123380785e-22 4.4719227004564126e-21 1.8925442046736734e-21 23165/5903/55706/7175/9631/91754/140609/348995/79023/9133/57122/23636/10762/23511/891/53371/983/23279/4927/9688/79902/9883/23225/8086/9972/8021/6396/129401/55746/8480 30 African_swine_fever_virus R-HSA-180746 Nuclear import of Rev protein 29/1415 33/10654 6.9660979581139185e-22 4.918839169312661e-21 2.08168190444223e-21 23165/3837/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/9972/8021/6396/129401/1104/55746/8480 29 African_swine_fever_virus R-HSA-933542 TRAF6 mediated NF-kB activation 24/1415 24/10654 7.654655038813827e-22 5.37517489189634e-21 2.274805888243016e-21 1147/351/7186/4790/6283/57506/4214/28512/7706/8517/5970/4792/4793/177/3146/23586/64135/6288/7189/6285/84282/3551/4791/28511 24 African_swine_fever_virus R-HSA-165054 Rev-mediated nuclear export of HIV RNA 29/1415 34/10654 4.139795453125489e-21 2.891032978528844e-20 1.2235022999115819e-20 23165/5905/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/7514/9972/8021/6396/129401/1104/55746/8480 29 African_swine_fever_virus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 23/1415 23/10654 5.846022824542383e-21 4.0602704972641366e-20 1.7183305512459926e-20 11065/246184/7321/991/8697/8881/7316/891/983/51433/119504/51529/7324/64682/29945/10393/6233/51434/7311/25906/29882/7314/996 23 African_swine_fever_virus R-HSA-5689603 UCH proteinases 53/1415 102/10654 7.1883492362018275e-021 4.965430369137241e-20 2.101399576486919e-20 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/580/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/8473/5702/5719/5704/6233/5716/7311/60/7040/7345/5694/5693/5721/5696/5691/7314 53 African_swine_fever_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 46/1415 80/10654 1.0958371168099205e-20 7.528697164677887e-20 3.1861892841528844e-20 3839/23165/3837/3838/5903/402569/55706/7175/9631/348995/79023/57122/23636/7706/10762/23511/7316/53371/6772/23279/4927/9688/79902/23586/3840/9883/23225/3661/8086/7324/3836/4599/6233/3716/7311/9972/5300/8021/6396/129401/7334/55746/5495/8480/7314/5595 46 African_swine_fever_virus R-HSA-382556 ABC-family proteins mediated transport 53/1415 103/10654 1.2937457425442465e-20 8.840595907385685e-20 3.741392611432428e-20 5718/5689/5684/5720/5682/5700/122706/5707/79139/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/335/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/11160/5694/5693/5721/5696/10058/5691/7314 53 African_swine_fever_virus R-HSA-168253 Host Interactions with Influenza Factors 32/1415 42/10654 2.468171496198066e-20 1.6775646907314127e-19 7.099553248281519e-20 3839/23165/3837/3838/5903/402569/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/3840/9883/23225/8086/3836/9972/8021/7040/6396/129401/55746/8480 32 African_swine_fever_virus R-HSA-2559583 Cellular Senescence 77/1415 195/10654 2.579162254546047e-20 1.7436783114510775e-19 7.379350011607112e-20 1017/3725/9134/1019/5601/11065/4790/5606/9448/3159/246184/1029/7027/7321/2146/6045/8697/5594/1027/898/7295/5925/1051/472/79813/3576/8881/7316/1869/890/6774/5970/1026/9261/6667/7867/51433/4194/3552/1432/10524/5602/23512/1021/119504/7157/8900/51529/7324/4001/64682/29945/10393/8091/23112/5609/6233/51434/2353/51343/7311/25906/29882/5599/5600/4217/26523/3456/6416/5608/3569/10919/7314/996/5595/4193/23043 77 African_swine_fever_virus R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 28/1415 33/10654 2.7062921884011315e-20 1.8103670376093885e-19 7.661580655251957e-20 23165/3303/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/7514/9972/8021/6396/129401/55746/8480 28 African_swine_fever_virus R-HSA-180910 Vpr-mediated nuclear import of PICs 28/1415 33/10654 2.7062921884011315e-20 1.8103670376093885e-19 7.661580655251957e-20 23165/5903/55706/7175/9631/3159/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8815/8086/3836/9972/8021/6396/129401/55746/8480 28 African_swine_fever_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 37/1415 55/10654 3.0449110390954896e-20 2.0262209061206112e-19 8.575087026606753e-20 1147/834/596/351/4790/6885/842/835/7295/330/23118/841/8517/7316/7335/5970/64127/7128/1432/329/598/10628/3656/10454/3654/7189/6233/7311/114548/5600/7334/1540/3551/5608/4791/7314/257397 37 African_swine_fever_virus R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 27/1415 31/10654 3.144190903869112e-20 2.070604476071317e-19 8.762920926518224e-20 23165/3837/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/3836/9972/8021/6396/129401/55746/8480 27 African_swine_fever_virus R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 27/1415 31/10654 3.144190903869112e-20 2.070604476071317e-19 8.762920926518224e-20 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/7514/9972/8021/6396/129401/55746/8480 27 African_swine_fever_virus R-HSA-5633007 Regulation of TP53 Activity 68/1415 160/10654 3.7891461009120644e-20 2.482476646525378e-19 1.050598837529064e-19 1017/6875/6118/5170/9156/1763/1029/1459/207/22974/9212/6878/545/472/117584/79813/580/7316/6872/890/1457/54971/983/6790/641/4194/5519/1432/5571/10524/10848/1616/9099/5985/2033/1111/3066/3065/7157/8900/5984/8626/5371/6233/5527/2475/672/5932/7311/7161/5518/6880/6908/10419/5300/5983/6117/5600/7159/7874/6882/1020/5608/10919/7314/4193/5515/5516 68 African_swine_fever_virus R-HSA-168276 NS1 Mediated Effects on Host Pathways 31/1415 40/10654 4.030966686801484e-20 2.6273634148331723e-19 1.1119157770340397e-19 3839/23165/3837/3838/5903/402569/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/3840/9883/23225/8086/3836/9972/8021/6396/129401/55746/8480 31 African_swine_fever_virus R-HSA-176033 Interactions of Vpr with host cellular proteins 29/1415 36/10654 9.485828735345044e-20 6.151269552358955e-19 2.6032537506773997e-19 23165/5903/55706/7175/9631/3159/348995/79023/57122/23636/10762/23511/53371/292/23279/4927/9688/79902/9883/23225/8815/8086/3836/9972/8021/6396/129401/55746/8480 29 African_swine_fever_virus R-HSA-8951664 Neddylation 85/1415 234/10654 1.5328294939756292e-19 9.889473537274237e-19 4.1852838440905505e-19 8454/5718/51397/5689/8945/5684/5720/149951/23363/5682/5700/122706/7321/5707/9021/5690/9817/5717/9491/23198/6500/3091/143471/5706/5705/10197/28991/332/7323/9306/7316/10213/5709/9978/5695/5714/7704/9861/7322/5715/5711/5701/5688/5687/26270/6502/23291/170622/5685/5683/5698/5708/5692/5686/5713/55294/5699/5710/10987/5702/8453/5719/8139/5704/6233/2873/5716/7311/83987/8533/5694/51122/54939/54951/5693/5721/5696/5691/150684/50813/9820/7314/51514/8451/899 85 African_swine_fever_virus R-HSA-68875 Mitotic Prophase 62/1415 142/10654 3.3852972361944274e-19 2.1730872662642007e-18 9.196634171692464e-19 4000/23165/4926/5903/55706/7175/5579/9631/91754/2801/5578/5594/140609/5861/5925/348995/79023/9133/57122/23636/23310/7443/10762/10051/23511/10776/891/53371/983/23279/4927/9688/79902/8615/5519/81876/9883/2029/23225/8815/9663/8086/64900/4001/23175/9972/5518/55844/5347/54892/8021/6396/129401/84930/64689/55746/10592/29781/8480/5595/5515/5516 62 African_swine_fever_virus R-HSA-176187 Activation of ATR in response to replication stress 29/1415 37/10654 3.8342635308559615e-19 2.4489190692049885e-18 1.0363970718156023e-18 1017/4172/6118/5000/8318/23594/8317/63967/4173/545/4174/993/84515/4171/4998/10926/5985/990/995/4175/1111/5984/55388/23595/5983/6117/5001/4999/4176 29 African_swine_fever_virus R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs 58/1415 130/10654 1.3772164311873217e-18 8.75221042019543e-18 3.703987349140639e-18 5718/5689/25/5684/5720/902/2624/5682/5700/122706/5707/5690/5717/9491/23198/4005/143471/5706/5705/10197/7316/10213/5709/865/5695/4331/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/861/5719/5704/6233/5716/7311/6688/7161/5694/1022/5693/5721/5696/5691/7314 58 African_swine_fever_virus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 29/1415 38/10654 1.4148911647254047e-18 8.946898857542236e-18 3.786380650299459e-18 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/7341/23225/8086/7329/5371/9972/8021/6396/129401/55746/8480/4193 29 African_swine_fever_virus R-HSA-168638 NOD1/2 Signaling Pathway 28/1415 36/10654 2.3039539772914124e-18 1.4496660916521707e-17 6.135072862928149e-18 1147/834/6885/842/835/330/23118/841/8517/7316/7335/64127/7128/1432/329/3656/10454/3654/7189/6233/7311/5600/7334/1540/3551/5608/7314/257397 28 African_swine_fever_virus R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 20/1415 20/10654 2.594417389651672e-18 1.6164237756114094e-17 6.840801269927784e-18 11065/246184/7321/991/8697/8881/4085/51433/119504/51529/7324/64682/29945/10393/51434/701/9184/25906/29882/996 20 African_swine_fever_virus R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 20/1415 20/10654 2.594417389651672e-18 1.6164237756114094e-17 6.840801269927784e-18 11065/246184/7321/991/8697/8881/4085/51433/119504/51529/7324/64682/29945/10393/51434/701/9184/25906/29882/996 20 African_swine_fever_virus R-HSA-4085377 SUMOylation of SUMOylation proteins 27/1415 34/10654 3.590364935255266e-18 2.226026259858265e-17 9.420675131786601e-18 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/7341/23225/8086/7329/9972/8021/6396/129401/55746/8480 27 African_swine_fever_virus R-HSA-983169 Class I MHC mediated antigen processing & presentation 111/1415 371/10654 1.1059632504221846e-17 6.823685880032023e-17 2.88782432787806e-17 8454/1147/5718/5689/8945/5684/5720/11065/653361/142678/5682/246184/8916/5700/122706/7321/5707/991/10273/9021/8697/5690/9817/5717/9491/23198/6500/143471/5706/5705/10333/10197/7099/8517/4615/8881/23376/7323/7316/10213/5709/9978/5695/29927/7335/7096/7337/5714/7704/8651/51433/9861/7322/5715/5711/5701/5688/5687/26270/6502/23291/5685/10616/5683/3309/5698/5708/5692/5686/5713/55294/5699/7328/5710/5702/8453/51529/7324/63891/5719/10075/64682/29945/10393/8139/5704/6233/51434/4012/5716/51343/7311/6047/29882/6396/7334/5694/7097/3551/7332/5693/5721/5696/997/64320/5691/9820/7314/996/4360/899 111 African_swine_fever_virus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 98/1415 309/10654 1.3088948390681639e-17 8.036740775148e-17 3.401196352727342e-17 8454/5718/5689/8945/5684/5720/11065/142678/5682/246184/8916/5700/122706/7321/5707/991/10273/9021/8697/5690/9817/5717/9491/23198/6500/143471/5706/5705/10197/8881/23376/7323/7316/10213/5709/9978/5695/7335/7337/5714/7704/8651/51433/9861/7322/5715/5711/5701/5688/5687/26270/6502/23291/5685/10616/5683/5698/5708/5692/5686/5713/55294/5699/7328/5710/5702/8453/51529/7324/63891/5719/10075/64682/29945/10393/8139/5704/6233/51434/4012/5716/51343/7311/6047/29882/7334/5694/7332/5693/5721/5696/997/64320/5691/9820/7314/996/899 98 African_swine_fever_virus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 27/1415 35/10654 1.3730878104470497e-17 8.390358687875962e-17 3.5508495502957606e-17 23165/5903/55706/7175/9631/7884/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/10189/8086/9972/8021/6396/129401/55746/8480 27 African_swine_fever_virus R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 19/1415 19/10654 1.976477717689505e-17 1.1962396091349337e-16 5.062556961099434e-17 11065/246184/7321/991/8697/8881/51433/119504/51529/8556/7324/64682/29945/10393/51434/51343/25906/29882/996 19 African_swine_fever_virus R-HSA-176412 Phosphorylation of the APC/C 19/1415 19/10654 1.976477717689505e-17 1.1962396091349337e-16 5.062556961099434e-17 11065/246184/7321/8697/8881/891/983/51433/119504/51529/7324/64682/29945/10393/51434/25906/5347/29882/996 19 African_swine_fever_virus R-HSA-68962 Activation of the pre-replicative complex 26/1415 33/10654 2.1833239598714504e-17 1.3151681293822813e-16 5.565869511071645e-17 1017/4172/6118/5000/8318/23594/8317/4173/5557/5422/4174/84515/4171/51053/4998/10926/5427/990/4175/81620/55388/23595/6117/5001/4999/4176 26 African_swine_fever_virus R-HSA-156902 Peptide chain elongation 45/1415 89/10654 2.587523940405664e-17 1.5512938340828296e-16 6.565167495269584e-17 6158/6138/9349/4736/6206/6194/6191/6128/1938/6129/1915/6222/6176/6136/6125/6224/6146/51065/6154/6202/6232/6164/6155/6218/6229/6231/6130/6204/6228/23521/6235/6181/6124/6207/6139/6233/7311/6223/6188/6135/6137/6170/6122/6133/6230 45 African_swine_fever_virus R-HSA-913531 Interferon Signaling 73/1415 199/10654 3.2297480003570206e-17 1.9272346049078747e-16 8.156171130133124e-17 3839/23165/3665/5777/3837/3838/5903/10379/402569/55706/7175/960/5770/9631/7412/9021/348995/79023/3383/57122/23636/7706/10762/3662/23511/7316/3394/53371/3663/3664/6772/8651/23279/4927/9688/3659/79902/23586/3840/1958/25939/9883/7341/3717/23225/3458/3661/8086/7324/3836/5371/3439/4599/6233/5580/3716/7311/9972/5300/8021/6396/129401/7334/3456/7297/4261/55746/5696/3660/5495/8480/7314/5595 73 African_swine_fever_virus R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 25/1415 31/10654 3.293906633143523e-17 1.947235037546706e-16 8.240814147056745e-17 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/6396/129401/55746/8480 25 African_swine_fever_virus R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 25/1415 31/10654 3.293906633143523e-17 1.947235037546706e-16 8.240814147056745e-17 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/6396/129401/55746/8480 25 African_swine_fever_virus R-HSA-156842 Eukaryotic Translation Elongation 46/1415 93/10654 3.490165047377866e-17 2.053703599637624e-16 8.691395415253848e-17 6158/6138/9349/4736/6206/6194/6191/6128/1938/6129/1915/1936/6222/6176/6136/6125/6224/6146/51065/6154/6202/6232/6164/6155/6218/6229/6231/6130/6204/6228/23521/6235/6181/6124/6207/6139/6233/7311/6223/6188/6135/6137/6170/6122/6133/6230 46 African_swine_fever_virus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 41/1415 77/10654 6.120379203238941e-17 3.584793533325665e-16 1.5171058805991264e-16 23165/5903/55706/7175/9631/1029/6045/10274/348995/79023/57122/23636/10735/10762/5885/23511/53371/641/23279/4927/9688/79902/9883/7341/23225/8243/9126/142/1069/8086/7329/5371/672/9972/6612/8021/6117/6396/129401/55746/8480 41 African_swine_fever_virus R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 22/1415 25/10654 6.867985245613348e-17 4.0042244253094338e-16 1.6946115212498412e-16 1017/994/902/2305/9133/891/993/890/4331/983/5519/9088/995/5520/8900/7514/5518/5347/7465/1022/5515/5516 22 African_swine_fever_virus R-HSA-159227 Transport of the SLBP independent Mature mRNA 26/1415 34/10654 8.11225822549561e-17 4.708073152787635e-16 1.9924844764375182e-16 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/10189/8086/9972/8021/6396/129401/55746/8480 26 African_swine_fever_virus R-HSA-201681 TCF dependent signaling in response to WNT 80/1415 233/10654 8.53893563064155e-17 4.933175993884277e-16 2.0877493336161877e-16 5718/5689/8945/5684/857/5720/7015/6597/5682/1499/5525/1459/5700/122706/5707/5526/207/1454/5690/5717/9491/23198/143471/5706/5705/10197/6657/5528/7316/10213/5709/9978/5695/1457/5714/4609/9861/5715/5519/5711/2932/5701/10524/5688/1387/5687/5685/5683/5698/5708/5692/5686/5713/2033/5699/5529/5710/5702/3065/7088/5719/5704/6233/5527/5716/7514/7311/5518/331/5694/5693/5721/5696/6259/5691/7314/4221/123169/5515/5516 80 African_swine_fever_virus R-HSA-6783783 Interleukin-10 signaling 31/1415 47/10654 8.624242007077611e-17 4.959914747056852e-16 2.099065332515675e-16 3557/7124/1437/6351/3593/3553/2919/5743/941/3383/3576/2920/6352/6774/1435/6348/1440/3627/7133/3606/6364/7132/3552/942/3716/6347/7297/3569/1234/3586/3554 31 African_swine_fever_virus R-HSA-195721 Signaling by WNT 100/1415 331/10654 2.425026253792253e-16 1.3883821480044837e-15 5.875715579363875e-16 8454/5718/5689/27161/8945/5684/857/5720/7015/6885/5579/6597/5682/1499/5525/1459/4772/5700/122706/5707/5526/207/1454/5690/5578/5717/9491/23198/6500/409/143471/5706/5705/10197/6657/5528/7316/10213/5709/9978/5695/1457/5714/4609/9861/5715/5881/5519/5711/2932/5701/10524/5688/1387/5687/5685/5683/5698/5708/5880/5692/5686/5713/2033/5699/5529/5710/5702/3065/7088/5719/23112/5704/6233/5527/5716/7514/163/7311/5518/1213/331/808/3845/5694/1175/26523/801/5693/5721/5696/6259/5691/7314/5879/4221/805/123169/5515/5516 100 African_swine_fever_virus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 21/1415 24/10654 4.612954372456441e-16 2.6291771333597026e-15 1.11268335346955e-15 6885/5606/23118/8517/7316/7335/9261/7867/64127/1432/3656/10454/3654/7189/6233/7311/5600/7334/5608/7314/257397 21 African_swine_fever_virus R-HSA-194138 Signaling by VEGF 48/1415 107/10654 1.0076627201480205e-15 5.717586237982741e-15 2.4197164003554442e-15 5295/5170/5590/4893/857/5290/653361/5579/1499/5567/7424/207/7422/5578/5568/3315/57761/5921/8829/9261/10768/6714/7867/5566/1003/1432/3320/2534/9475/3690/4846/3728/998/5580/2324/2475/6093/9844/3791/60/808/3845/5600/3265/5058/801/5879/805 48 African_swine_fever_virus R-HSA-192823 Viral mRNA Translation 43/1415 89/10654 1.1298489746283787e-15 6.382391318900753e-15 2.7010658527957967e-15 6158/6138/9349/4736/6206/6194/6191/6128/6129/6222/6176/6136/6125/6224/6146/51065/6154/6202/6232/6164/6155/6218/6229/6231/6130/6204/6228/23521/6235/6181/6124/6207/6139/6233/7311/6223/6188/6135/6137/6170/6122/6133/6230 43 African_swine_fever_virus R-HSA-162587 HIV Life Cycle 59/1415 152/10654 1.889476931045347e-15 1.0626217607781575e-14 4.49707830351268e-15 23165/6875/5905/2237/5903/7852/902/55706/7175/9631/3159/2959/5430/6878/348995/79023/57122/23636/3978/10762/23511/7316/6872/2960/53371/4331/23279/4927/9688/79902/2962/9883/8812/23225/8815/905/2068/5901/8086/3836/6233/7514/1025/7311/9972/6880/6908/8021/6396/129401/904/1104/6882/1022/55746/1234/8480/2957/7314 59 African_swine_fever_virus R-HSA-69190 DNA strand elongation 24/1415 32/10654 2.7524503152150272e-15 1.5411296698847134e-14 6.522152149663246e-15 4172/6118/2237/8318/1763/57804/9837/4173/3978/5557/5422/4174/5425/84515/5111/4171/5985/4175/5984/51659/5983/6117/5981/4176 24 African_swine_fever_virus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 20/1415 23/10654 3.079084475255296e-15 1.7164545473901233e-14 7.264137427772189e-15 5601/6885/23118/8517/7316/7335/64127/5602/3656/10454/3654/7189/5609/6233/7311/5599/7334/6416/7314/257397 20 African_swine_fever_virus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 44/1415 95/10654 3.7511216263299885e-15 2.081954404832059e-14 8.810954498067683e-15 6158/6138/9349/4736/6206/6194/6191/6128/6129/6222/6176/6136/6125/6224/6146/51065/6154/26986/6202/6232/6164/6155/6218/6229/6231/6130/6204/6228/23521/6235/6181/6124/6207/6139/6233/7311/6223/6188/6135/6137/6170/6122/6133/6230 44 African_swine_fever_virus R-HSA-4420097 VEGFA-VEGFR2 Pathway 45/1415 99/10654 4.36112352331818e-15 2.4099947817988723e-14 1.019924082570064e-14 5295/5170/5590/4893/857/5290/653361/5579/1499/5567/207/7422/5578/5568/3315/57761/5921/9261/10768/6714/7867/5566/1003/1432/3320/2534/9475/3690/4846/3728/998/5580/2475/6093/9844/3791/60/808/3845/5600/3265/5058/801/5879/805 45 African_swine_fever_virus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 30/1415 49/10654 5.544913680377681e-15 3.0509027219740404e-14 1.2911601233415336e-14 1017/9134/7027/1027/4869/898/2810/5934/1869/891/890/10769/983/1026/6790/5933/5111/1647/28984/2033/995/1874/7157/8900/10498/55835/3276/144455/79733/29883 30 African_swine_fever_virus R-HSA-2408557 Selenocysteine synthesis 43/1415 93/10654 8.34353666362853e-15 4.551345536254017e-14 1.9261564197488946e-14 6158/6138/9349/4736/6206/6194/6191/6128/6129/6222/6176/6136/6125/6224/6146/51065/6154/6202/6232/6164/6155/6218/6229/6231/6130/6204/6228/23521/6235/6181/6124/6207/6139/6233/7311/6223/6188/6135/6137/6170/6122/6133/6230 43 African_swine_fever_virus R-HSA-72764 Eukaryotic Translation Termination 43/1415 93/10654 8.34353666362853e-15 4.551345536254017e-14 1.9261564197488946e-14 6158/6138/9349/4736/6206/6194/6191/6128/6129/6222/6176/6136/6125/6224/6146/51065/6154/6202/6232/6164/6155/6218/6229/6231/6130/6204/6228/23521/6235/6181/6124/6207/6139/6233/7311/6223/6188/6135/6137/6170/6122/6133/6230 43 African_swine_fever_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 16/1415 16/10654 8.706189271831241e-15 4.72887460021261e-14 2.001287772337276e-14 8454/1147/8945/1326/4790/5604/6500/8517/7316/79155/23291/6233/7311/3551/6416/7314 16 African_swine_fever_virus R-HSA-6804757 Regulation of TP53 Degradation 25/1415 36/10654 1.3737922219609828e-14 7.430169847286846e-14 3.14449193918057e-14 1017/5170/1029/207/472/117584/7316/890/983/4194/5519/1616/9099/7157/8900/6233/5527/2475/7311/5518/7874/7314/4193/5515/5516 25 African_swine_fever_virus R-HSA-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 17/1415 18/10654 1.8050936411851447e-14 9.721500076043723e-14 4.1141964792400046e-14 8792/4050/7186/8600/330/10673/9020/329/4049/8740/115650/7187/51330/958/8742/959/4055 17 African_swine_fever_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 18/1415 20/10654 2.191920054353187e-14 1.1656612506623017e-13 4.933147534791802e-14 1147/11035/7321/8737/330/8517/7098/7323/7316/7335/7322/329/7189/6233/7311/7334/3551/7314 18 African_swine_fever_virus R-HSA-5213460 RIPK1-mediated regulated necrosis 18/1415 20/10654 2.191920054353187e-14 1.1656612506623017e-13 4.933147534791802e-14 11035/7186/8737/355/330/841/7316/8797/329/8837/197259/6233/7311/8772/331/8717/8743/7314 18 African_swine_fever_virus R-HSA-5218859 Regulated Necrosis 18/1415 20/10654 2.191920054353187e-14 1.1656612506623017e-13 4.933147534791802e-14 11035/7186/8737/355/330/841/7316/8797/329/8837/197259/6233/7311/8772/331/8717/8743/7314 18 African_swine_fever_virus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 27/1415 42/10654 2.2461057367500952e-14 1.189500163087238e-13 5.034035225786398e-14 23165/5903/55706/7175/9631/7884/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/10189/8086/9972/8021/6396/129401/55746/8480 27 African_swine_fever_virus R-HSA-927802 Nonsense-Mediated Decay (NMD) 48/1415 115/10654 3.09974421952246e-14 1.6280061582698542e-13 6.88981860015649e-14 10921/6158/6138/9349/4736/6206/6194/6191/6128/6129/6222/6176/6136/6125/6224/6146/51065/6154/26986/6202/6232/6164/6155/6218/6229/6231/6130/6204/6228/23521/6235/6181/6124/5520/6207/6139/6233/7311/6223/5518/6188/6135/6137/6170/6122/6133/5515/6230 48 African_swine_fever_virus R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 48/1415 115/10654 3.09974421952246e-14 1.6280061582698542e-13 6.88981860015649e-14 10921/6158/6138/9349/4736/6206/6194/6191/6128/6129/6222/6176/6136/6125/6224/6146/51065/6154/26986/6202/6232/6164/6155/6218/6229/6231/6130/6204/6228/23521/6235/6181/6124/5520/6207/6139/6233/7311/6223/5518/6188/6135/6137/6170/6122/6133/5515/6230 48 African_swine_fever_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 25/1415 37/10654 3.7040109616090495e-14 1.9373654041996305e-13 8.199045273477256e-14 1017/5170/1029/207/472/117584/7316/890/983/4194/5519/1616/9099/7157/8900/6233/5527/2475/7311/5518/7874/7314/4193/5515/5516 25 African_swine_fever_virus R-HSA-168325 Viral Messenger RNA Synthesis 27/1415 43/10654 5.2773661075863986e-14 2.7489886568616034e-13 1.1633883006801767e-13 23165/5903/55706/7175/9631/5430/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/2962/9883/23225/8086/9972/8021/6396/129401/55746/8480 27 African_swine_fever_virus R-HSA-5689896 Ovarian tumor domain proteases 25/1415 38/10654 9.46787550031764e-14 4.911701943226009e-13 2.0786613880396624e-13 56957/7321/8737/57506/7706/8517/7316/79155/80124/983/2099/7415/23586/64127/7128/64135/5728/7157/7189/6233/7311/84282/7187/10318/7314 25 African_swine_fever_virus R-HSA-8939211 ESR-mediated signaling 72/1415 223/10654 1.1037867058946123e-13 5.695598061713789e-13 2.410410873771789e-13 5295/5170/27161/3725/3838/596/5590/4893/857/5290/5241/7031/5430/207/5451/5594/2069/6722/1027/3315/10274/4318/10735/5885/4313/1950/865/1655/4314/6667/7033/6714/2099/4609/2962/8850/10524/1387/3320/2033/8243/4846/9126/595/3065/861/23028/23112/10498/7514/1385/1025/2353/1386/6908/1956/3169/808/3845/904/3276/7392/3265/26523/801/8202/3480/10728/2957/5595/805/6387 72 African_swine_fever_virus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 26/1415 41/10654 1.1068550127799417e-13 5.695598061713789e-13 2.410410873771789e-13 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/10189/8086/9972/8021/6396/129401/55746/8480 26 African_swine_fever_virus R-HSA-4570464 SUMOylation of RNA binding proteins 28/1415 47/10654 1.2087308111918385e-13 6.194745407358172e-13 2.6216529903184613e-13 23165/5903/55706/7175/9631/6045/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/7341/23225/8086/7329/9972/8021/6396/129401/55746/8480 28 African_swine_fever_virus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 16/1415 17/10654 1.2968604666224085e-13 6.619717482237274e-13 2.8015036924288765e-13 1147/11035/4790/8737/28512/8517/4615/7098/5970/4792/4793/1660/81030/3551/4791/28511 16 African_swine_fever_virus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 18/1415 21/10654 1.3435382825845438e-13 6.830548628659821e-13 2.8907286837924294e-13 1147/11035/4790/8737/29110/28512/8517/4615/7098/5970/4792/4793/1660/3661/81030/3551/4791/28511 18 African_swine_fever_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 41/1415 92/10654 1.6577003251695055e-13 8.394171766097377e-13 3.552463267610054e-13 1017/6875/6118/9156/1763/1459/22974/9212/6878/545/472/580/7316/6872/890/1457/6790/641/4194/1432/5571/10524/5985/1111/7157/8900/5984/6233/672/5932/7311/6880/6908/5300/5983/6117/5600/6882/1020/7314/4193 41 African_swine_fever_virus R-HSA-70171 Glycolysis 35/1415 71/10654 2.4436920720055966e-13 1.232512945840918e-12 5.216067872994402e-13 23165/5903/2597/55706/7175/9631/5315/5567/5568/348995/79023/57122/23636/10762/23511/5528/53371/23279/4927/9688/79902/5566/5519/9883/23225/8086/9972/5518/8021/6396/129401/55746/8480/5515/5516 35 African_swine_fever_virus R-HSA-72689 Formation of a pool of free 40S subunits 43/1415 101/10654 2.9849288464003644e-13 1.4995433058398668e-12 6.346156191015546e-13 6158/6138/9349/4736/6206/6194/6191/6128/6129/6222/6176/6136/6125/6224/6146/51065/6154/6202/6232/6164/6155/6218/6229/6231/6130/6204/6228/23521/6235/6181/6124/6207/6139/6233/7311/6223/6188/6135/6137/6170/6122/6133/6230 43 African_swine_fever_virus R-HSA-162599 Late Phase of HIV Life Cycle 52/1415 139/10654 5.030423072065535e-13 2.5171920175572026e-12 1.0652905884067502e-12 23165/6875/5905/5903/902/55706/7175/9631/2959/5430/6878/348995/79023/57122/23636/10762/23511/7316/6872/2960/53371/4331/23279/4927/9688/79902/2962/9883/8812/23225/905/2068/5901/8086/6233/7514/1025/7311/9972/6880/6908/8021/6396/129401/904/1104/6882/1022/55746/8480/2957/7314 52 African_swine_fever_virus R-HSA-113510 E2F mediated regulation of DNA replication 18/1415 22/10654 6.470823774232132e-13 3.2252615753133492e-12 1.3649498239969535e-12 5000/23594/7027/5925/5557/5422/1869/891/983/84515/5519/4998/23595/5518/5001/4999/5515/5516 18 African_swine_fever_virus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 22/1415 32/10654 7.553981929783817e-13 3.7504339971700125e-12 1.5872059071215177e-12 892/7027/7316/1875/1024/6667/5933/4609/4089/22938/8812/4088/1874/905/3065/6233/1025/7311/904/7314/4221/5054 22 African_swine_fever_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 119/1415 473/10654 8.380724150988536e-13 4.1447083252554205e-12 1.7540651407557411e-12 5295/54106/5170/5777/627/5590/9252/4893/857/5290/2670/653361/5241/5579/5770/5604/1499/5340/5567/7424/5430/10273/207/7422/5578/9114/5594/2069/5568/1785/3315/3082/3178/23118/51741/4318/2064/57761/5921/1280/6778/348/8829/5528/9306/7316/1950/3185/6774/9261/10768/6772/6714/2099/8651/5605/7867/5566/5802/2962/1447/5519/1003/5795/1432/4670/4067/3717/2247/4914/3320/2335/2534/9475/3690/4846/3728/4803/1111/3630/998/6868/3925/6285/6233/5580/2324/2475/6093/1385/163/9844/7311/3932/3479/5518/1213/3791/1956/60/29924/5581/808/3845/5600/3265/1175/5058/801/1020/3480/11140/7314/5879/5595/805/5515/6387/5516 119 African_swine_fever_virus R-HSA-191859 snRNP Assembly 29/1415 53/10654 8.981748764460998e-13 4.4032511568380615e-12 1.8634820002022852e-12 23165/50628/6635/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/6634/10419/8021/6396/129401/55746/8480 29 African_swine_fever_virus R-HSA-194441 Metabolism of non-coding RNA 29/1415 53/10654 8.981748764460998e-13 4.4032511568380615e-12 1.8634820002022852e-12 23165/50628/6635/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/6634/10419/8021/6396/129401/55746/8480 29 African_swine_fever_virus R-HSA-71291 Metabolism of amino acids and derivatives 100/1415 372/10654 9.007437456946466e-13 4.4032511568380615e-12 1.8634820002022852e-12 6158/5718/5689/6138/5684/9349/4736/1728/5720/6206/6194/6191/6128/5682/6129/3620/5700/3028/122706/5707/25828/6222/1743/6176/383/5690/6136/6125/5717/9491/23198/6224/6146/51065/6154/143471/6202/5706/5705/10197/6232/6164/6155/10213/5709/6218/5695/5409/5714/6229/6231/9861/6130/5715/5711/6204/5701/5688/6228/23521/5687/23474/5685/5683/5698/5708/5692/5686/5713/5699/6235/5710/6181/6124/5702/6207/5719/6139/5704/6233/5716/7311/6223/1644/1738/6188/6135/6303/5694/2744/5693/5721/6137/5696/6170/5691/2875/6122/6133/6230 100 African_swine_fever_virus R-HSA-193639 p75NTR signals via NF-kB 15/1415 16/10654 9.279802770712441e-13 4.519015065737744e-12 1.9124739729114975e-12 4804/4790/5584/8878/4615/7316/5970/4792/4803/3654/7189/6233/7311/3551/7314 15 African_swine_fever_virus R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 45/1415 112/10654 1.0081840321395426e-12 4.890846965073888e-12 2.069835437618748e-12 6158/6138/9349/4736/6206/6194/6191/6128/6129/6222/6176/6136/6125/6727/6224/6146/51065/6154/6202/6232/6164/6155/6218/29927/6229/6231/6130/6204/6228/23521/6235/6181/6124/6207/6139/6233/7311/6223/6188/6135/6137/6170/6122/6133/6230 45 African_swine_fever_virus R-HSA-5675482 Regulation of necroptotic cell death 16/1415 18/10654 1.0227669286653558e-12 4.942725347276301e-12 2.091790676597946e-12 7186/8737/355/330/841/7316/8797/329/8837/6233/7311/8772/331/8717/8743/7314 16 African_swine_fever_virus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 26/1415 44/10654 1.2010049299392116e-12 5.782110855881583e-12 2.4470236012716794e-12 892/7027/7321/7323/7316/1875/9612/1024/6667/5933/4609/4089/22938/8812/4088/1874/142/905/3065/6233/1025/7311/904/7314/4221/5054 26 African_swine_fever_virus R-HSA-69205 G1/S-Specific Transcription 20/1415 28/10654 2.775082768249109e-12 1.33099252771495e-11 5.632839303178926e-12 26271/8318/7027/898/5934/5422/1869/1875/983/5933/5111/4998/990/1874/81620/3065/8900/7298/7083/6241 20 African_swine_fever_virus R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 44/1415 111/10654 3.13443025311727e-12 1.4976920495158084e-11 6.338321564475366e-12 6158/6138/9349/4736/6206/6194/6191/6128/6129/6222/6176/6136/6125/6224/6146/51065/6154/26986/6202/6232/6164/6155/6218/6229/6231/6130/6204/6228/23521/6235/6181/6124/6207/6139/6233/7311/6223/6188/6135/6137/6170/6122/6133/6230 44 African_swine_fever_virus R-HSA-209560 NF-kB is activated and signals survival 13/1415 13/10654 3.813632147683419e-12 1.8086292760095616e-11 7.654226345114797e-12 4804/4790/8878/7316/5970/4792/4803/3654/7189/6233/7311/3551/7314 13 African_swine_fever_virus R-HSA-5357786 TNFR1-induced proapoptotic signaling 13/1415 13/10654 3.813632147683419e-12 1.8086292760095616e-11 7.654226345114797e-12 7124/7186/56957/8737/7375/841/27005/7128/7132/9099/8772/8717/1540 13 African_swine_fever_virus R-HSA-389513 CTLA4 inhibitory signaling 17/1415 21/10654 4.034098222585247e-12 1.9060739185523603e-11 8.066617850679169e-12 5525/5526/207/941/5528/6714/5519/4067/2534/5529/942/5527/3932/5518/1493/5515/5516 17 African_swine_fever_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 26/1415 47/10654 9.790767639158725e-12 4.6089132108780515e-11 1.9505194010175863e-11 8454/8841/2648/892/6500/3091/10013/7316/9978/9612/1024/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/7088/6233/7311/4851/7314 26 African_swine_fever_virus R-HSA-5673000 RAF activation 21/1415 32/10654 1.0107538553723803e-11 4.7404728788866984e-11 2.0061962326482283e-11 4893/5604/5525/5526/5528/6714/5605/5519/3717/5529/5894/5527/5518/808/3845/3265/801/5245/805/5515/5516 21 African_swine_fever_virus R-HSA-9006931 Signaling by Nuclear Receptors 83/1415 299/10654 1.3983627938462673e-11 6.534261437421345e-11 2.7653381875210622e-11 5295/5170/27161/3725/3838/596/5590/4893/8841/857/5290/1374/5241/7031/5430/207/5451/5594/2069/6722/1027/3315/10274/4318/10735/6720/348/5885/4313/19/1950/865/1655/4314/9612/6667/7033/6714/2099/4609/2962/8850/10524/1387/5467/6907/3320/2033/8243/4846/9126/595/3065/861/23028/6256/23112/10498/7514/1385/1025/2353/1738/1386/6908/1956/3169/808/3845/904/3276/7392/3265/26523/801/8202/3480/10728/2957/10062/5595/805/6387 83 African_swine_fever_virus R-HSA-1538133 G0 and Early G1 19/1415 27/10654 1.5135256241058406e-11 7.046487429445141e-11 2.982115264769943e-11 1017/9134/4605/7027/7153/898/5934/1869/1875/993/890/983/5933/5111/4609/990/1874/3065/8900 19 African_swine_fever_virus R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 43/1415 112/10654 1.9437796874169167e-11 9.016583878492339e-11 3.815871764387417e-11 6158/6138/9349/4736/6206/6194/6191/6128/6129/6222/6176/6136/6125/6224/6146/51065/6154/6202/6232/6164/6155/6218/6229/6231/6130/6204/6228/23521/6235/6181/6124/6207/6139/6233/7311/6223/6188/6135/6137/6170/6122/6133/6230 43 African_swine_fever_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 33/1415 73/10654 2.4115066641826538e-11 1.1145545346095102e-10 4.7168608819036795e-11 5590/892/7027/7321/10273/7323/7316/1875/5501/9612/1024/6667/5933/4609/4089/22938/8812/4088/1874/142/905/3065/5499/6233/7514/1025/7311/7040/904/5500/7314/4221/5054 33 African_swine_fever_virus R-HSA-9009391 Extra-nuclear estrogen signaling 34/1415 77/10654 2.6957627162555243e-11 1.2414182653481055e-10 5.253755713221103e-11 5295/5170/596/5590/4893/857/5290/207/5594/2069/6722/1027/3315/4318/4313/1950/4314/6714/2099/3320/4846/595/7514/1385/2353/1956/808/3845/3276/3265/801/3480/5595/805 34 African_swine_fever_virus R-HSA-937041 IKK complex recruitment mediated by RIP1 18/1415 25/10654 2.8561464354892964e-11 1.3105278409772188e-10 5.546231535379178e-11 1147/11035/7321/8737/330/7099/8517/7323/7316/7335/7322/329/7189/6233/7311/7334/3551/7314 18 African_swine_fever_virus R-HSA-388841 Costimulation by the CD28 family 32/1415 70/10654 3.3533629157681964e-11 1.533138225158769e-10 6.48833188170219e-11 5295/5170/5777/1326/5290/5525/5526/207/941/8764/57761/5528/9020/6714/5519/29126/4067/29851/2534/5529/998/942/5527/2475/3932/5518/5058/1493/940/5879/5515/5516 32 African_swine_fever_virus R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 15/1415 18/10654 3.637728738750581e-11 1.6571875365419313e-10 7.013315923416514e-11 7027/2810/5934/891/983/6790/5933/5111/1647/2033/995/1874/7157/10498/3276 15 African_swine_fever_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 30/1415 63/10654 3.8480058517818314e-11 1.74671979914811e-10 7.392221767896676e-11 1147/3665/11035/4790/1499/8737/29110/28512/8517/6778/4615/7098/5591/7316/51428/5970/4792/4793/3428/1387/2033/1660/3661/6233/7311/81030/3551/4791/7314/28511 30 African_swine_fever_virus R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 42/1415 110/10654 4.10630863819872e-11 1.8573374658898836e-10 7.860362293011974e-11 1017/3725/1019/11065/4790/246184/1029/7321/8697/5594/1027/1051/79813/3576/8881/7316/890/6774/5970/1026/51433/3552/1021/119504/8900/51529/7324/64682/29945/10393/6233/51434/2353/51343/7311/25906/29882/3569/10919/7314/996/5595 42 African_swine_fever_virus R-HSA-918233 TRAF3-dependent IRF activation pathway 13/1415 14/10654 4.685882680625053e-11 2.1119705273313623e-10 8.937984508396423e-11 3665/29110/57506/7706/23586/1387/2033/64135/3661/84282/7187/9641/3456 13 African_swine_fever_virus R-HSA-72613 Eukaryotic Translation Initiation 44/1415 119/10654 4.9449580918252976e-11 2.2130428643344903e-10 9.36572863203383e-11 6158/6138/9349/4736/6206/6194/6191/6128/6129/6222/6176/6136/6125/6224/6146/51065/6154/26986/6202/6232/6164/6155/6218/6229/6231/6130/6204/6228/23521/6235/6181/6124/6207/6139/6233/7311/6223/6188/6135/6137/6170/6122/6133/6230 44 African_swine_fever_virus R-HSA-72737 Cap-dependent Translation Initiation 44/1415 119/10654 4.9449580918252976e-11 2.2130428643344903e-10 9.36572863203383e-11 6158/6138/9349/4736/6206/6194/6191/6128/6129/6222/6176/6136/6125/6224/6146/51065/6154/26986/6202/6232/6164/6155/6218/6229/6231/6130/6204/6228/23521/6235/6181/6124/6207/6139/6233/7311/6223/6188/6135/6137/6170/6122/6133/6230 44 African_swine_fever_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 27/1415 53/10654 5.058564984838867e-11 2.2559424897298949e-10 9.547282390591547e-11 596/7531/1029/7027/842/7532/207/10971/5594/7533/2810/841/1869/8655/6774/598/836/3002/7157/8626/7161/331/5599/7159/637/140735/5595 27 African_swine_fever_virus R-HSA-4551638 SUMOylation of chromatin organization proteins 32/1415 71/10654 5.335995630989176e-11 2.3713463101354e-10 1.0035678201823589e-10 23165/5903/55706/7175/9631/6045/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/7341/23225/23512/3066/3065/8086/7329/9972/6612/8021/6396/129401/55746/8480 32 African_swine_fever_virus R-HSA-8848021 Signaling by PTK6 27/1415 54/10654 8.846843609094106e-11 3.9042841066522947e-10 1.6523161857628246e-10 1017/1019/4893/5770/207/9021/2069/1027/898/3091/2064/5921/10657/7316/1950/6774/6421/2908/595/6233/9844/7311/1956/3845/3265/7314/5879 27 African_swine_fever_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 27/1415 54/10654 8.846843609094106e-11 3.9042841066522947e-10 1.6523161857628246e-10 1017/1019/4893/5770/207/9021/2069/1027/898/3091/2064/5921/10657/7316/1950/6774/6421/2908/595/6233/9844/7311/1956/3845/3265/7314/5879 27 African_swine_fever_virus R-HSA-5218921 VEGFR2 mediated cell proliferation 16/1415 21/10654 9.155952655529966e-11 4.01283304316503e-10 1.698254739374161e-10 5170/5590/4893/5579/7422/5578/5921/10768/6714/5580/3791/808/3845/3265/801/805 16 African_swine_fever_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 16/1415 21/10654 9.155952655529966e-11 4.01283304316503e-10 1.698254739374161e-10 9252/4893/4790/5567/5568/5970/5566/1387/4067/2534/2033/5894/5971/3845/3265/5058 16 African_swine_fever_virus R-HSA-2408522 Selenoamino acid metabolism 43/1415 118/10654 1.4147035194601351e-10 6.178997158879147e-10 2.614988238177352e-10 6158/6138/9349/4736/6206/6194/6191/6128/6129/6222/6176/6136/6125/6224/6146/51065/6154/6202/6232/6164/6155/6218/6229/6231/6130/6204/6228/23521/6235/6181/6124/6207/6139/6233/7311/6223/6188/6135/6137/6170/6122/6133/6230 43 African_swine_fever_virus R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 27/1415 55/10654 1.5196141537256389e-10 6.614484895155092e-10 2.79928923054723e-10 3303/5241/11258/1783/10382/7277/10671/1780/1781/3305/8655/10121/7846/2908/3320/10376/51143/3301/10540/3306/367/10383/3312/140735/10728/829/1778 27 African_swine_fever_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 13/1415 15/10654 3.0847166118509367e-10 1.3381142708745874e-9 5.662978942539352e-10 54106/3665/4615/7316/7335/3654/7189/6233/51311/7311/7334/51284/7314 13 African_swine_fever_virus R-HSA-70326 Glucose metabolism 36/1415 91/10654 3.1645719457416636e-10 1.3680853547747125e-9 5.789818346845651e-10 23165/5903/2597/55706/7175/9631/5315/5567/5568/348995/79023/57122/23636/10762/6576/23511/5528/53371/23279/4927/9688/79902/5566/5519/9883/23225/8086/9972/5518/8021/6396/129401/55746/8480/5515/5516 36 African_swine_fever_virus R-HSA-209543 p75NTR recruits signalling complexes 12/1415 13/10654 3.302882696115542e-10 1.4230386124619843e-9 6.022383792025127e-10 4804/5584/8878/4615/7316/4803/3654/7189/6233/7311/3551/7314 12 African_swine_fever_virus R-HSA-5675221 Negative regulation of MAPK pathway 22/1415 40/10654 4.562643856970688e-10 1.9591622777735626e-9 8.291290934964515e-10 4893/5604/5525/5526/5594/5528/7316/5605/5519/5529/5894/6233/5527/7311/5518/1843/3845/3265/7314/5595/5515/5516 22 African_swine_fever_virus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 34/1415 84/10654 4.761439884970972e-10 2.037639762221584e-9 8.623412302747356e-10 6118/902/57804/3978/7316/9978/85015/4331/5425/5111/7341/10401/5427/5985/142/2068/10987/5984/1069/7329/6233/2873/7311/6612/60/8533/5983/6117/7334/5981/1022/50813/7314/8451 34 African_swine_fever_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 20/1415 34/10654 5.593053145593796e-10 2.3854934724999046e-9 1.0095549831855988e-9 7321/29110/57506/7706/8887/7323/7316/23586/7322/7128/64135/3661/6233/7311/84282/7187/5300/9641/1540/7314 20 African_swine_fever_virus R-HSA-9614085 FOXO-mediated transcription 29/1415 65/10654 5.761917247100678e-10 2.4492965956739e-9 1.036556843255922e-9 2308/857/7532/207/10971/1027/7295/2810/4287/6720/847/5934/1026/4089/8850/1647/9314/1387/4088/2908/10628/2033/3630/3066/3065/6648/56729/23411/10891 29 African_swine_fever_virus R-HSA-199418 Negative regulation of the PI3K/AKT network 40/1415 110/10654 6.679966913174255e-10 2.8300793155481595e-9 1.1977063482919455e-9 5295/5290/90865/5525/8870/5526/207/5594/2069/930/3082/941/2064/57761/4615/5528/1950/6714/2099/5519/2247/29851/5880/2534/5728/5529/3630/942/3654/7189/5527/3932/5518/1956/940/5879/5595/5515/3556/5516 40 African_swine_fever_virus R-HSA-400253 Circadian Clock 30/1415 70/10654 9.656945417117307e-10 4.077733430284418e-9 1.725720968052787e-9 8454/8945/8841/1374/10135/1454/6500/3091/6720/5465/7316/5501/1387/2908/6907/2033/6256/5499/10498/6233/1385/7311/23054/1386/23411/1453/5500/10891/7314/5054 30 African_swine_fever_virus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 38/1415 103/10654 1.105952628405966e-9 4.6545224857747775e-9 1.969821516610138e-9 5295/5290/90865/5525/8870/5526/207/5594/2069/930/3082/941/2064/4615/5528/1950/6714/2099/5519/2247/29851/5880/2534/5529/3630/942/3654/7189/5527/3932/5518/1956/940/5879/5595/5515/3556/5516 38 African_swine_fever_virus R-HSA-2465910 MASTL Facilitates Mitotic Progression 10/1415 10/10654 1.6612304362906754e-9 6.922701260739174e-9 2.929728224139897e-9 10776/891/983/5519/2029/5518/55844/84930/5515/5516 10 African_swine_fever_virus R-HSA-450341 Activation of the AP-1 family of transcription factors 10/1415 10/10654 1.6612304362906754e-9 6.922701260739174e-9 2.929728224139897e-9 3725/5601/5594/1432/5602/2353/1386/5599/5600/5595 10 African_swine_fever_virus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 10/1415 10/10654 1.6612304362906754e-9 6.922701260739174e-9 2.929728224139897e-9 6885/23118/7316/3656/10454/7189/6233/7311/7314/257397 10 African_swine_fever_virus R-HSA-5260271 Diseases of Immune System 16/1415 24/10654 2.228637257609933e-9 9.226703434600079e-9 3.904795606510118e-9 1147/81793/4790/10333/7099/8517/4615/7098/7100/5970/4792/7096/7187/7097/3551/4791 16 African_swine_fever_virus R-HSA-5602358 Diseases associated with the TLR signaling cascade 16/1415 24/10654 2.228637257609933e-9 9.226703434600079e-9 3.904795606510118e-9 1147/81793/4790/10333/7099/8517/4615/7098/7100/5970/4792/7096/7187/7097/3551/4791 16 African_swine_fever_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 11/1415 12/10654 2.3131763043855554e-9 9.514715478556767e-9 4.026684011381431e-9 3665/29110/7098/7316/3661/6233/10010/7311/7187/9641/7314 11 African_swine_fever_virus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 11/1415 12/10654 2.3131763043855554e-9 9.514715478556767e-9 4.026684011381431e-9 1147/8737/57506/841/7706/8517/23586/64135/84282/8772/3551 11 African_swine_fever_virus R-HSA-6784531 tRNA processing in the nucleus 26/1415 57/10654 2.4958348838582647e-9 1.0232923023818884e-8 4.330633703400928e-9 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/9972/8021/6396/129401/55746/8480 26 African_swine_fever_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 26/1415 58/10654 3.956880952519588e-9 1.5965700605245704e-8 6.7567791703843264e-9 8454/8841/142678/2648/892/6500/10013/7316/9978/9612/1024/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/6868/6233/7311/4851/7314 26 African_swine_fever_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 26/1415 58/10654 3.956880952519588e-9 1.5965700605245704e-8 6.7567791703843264e-9 8454/8841/142678/2648/892/6500/10013/7316/9978/9612/1024/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/6868/6233/7311/4851/7314 26 African_swine_fever_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 26/1415 58/10654 3.956880952519588e-9 1.5965700605245704e-8 6.7567791703843264e-9 8454/8841/142678/2648/892/6500/10013/7316/9978/9612/1024/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/6868/6233/7311/4851/7314 26 African_swine_fever_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 26/1415 58/10654 3.956880952519588e-9 1.5965700605245704e-8 6.7567791703843264e-9 8454/8841/142678/2648/892/6500/10013/7316/9978/9612/1024/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/6868/6233/7311/4851/7314 26 African_swine_fever_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 26/1415 58/10654 3.956880952519588e-9 1.5965700605245704e-8 6.7567791703843264e-9 8454/8841/142678/2648/892/6500/10013/7316/9978/9612/1024/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/6868/6233/7311/4851/7314 26 African_swine_fever_virus R-HSA-432142 Platelet sensitization by LDL 13/1415 17/10654 5.3882164308106865e-9 2.167222494797589e-8 9.171814111073488e-9 5777/5321/5525/5526/5175/5528/5519/1432/5529/5527/5518/5515/5516 13 African_swine_fever_virus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 18/1415 31/10654 5.536090898277964e-9 2.2196755620540352e-8 9.393798602092112e-9 3725/5601/9252/5594/5528/9261/5519/1432/5602/1385/2353/5518/1386/5599/5600/5595/5515/5516 18 African_swine_fever_virus R-HSA-2142753 Arachidonic acid metabolism 26/1415 59/10654 6.1881613869360106e-9 2.47331859207411e-8 1.0467230945793782e-8 5730/5321/242/113612/1558/3248/246/1559/5743/11283/1573/4051/5740/9261/8529/9536/239/80142/27306/247/6916/240/1579/5742/1557/10728 26 African_swine_fever_virus R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 30/1415 75/10654 6.970346200215442e-9 2.7772131725623282e-8 1.175333083091929e-8 10921/23165/5903/6432/6431/55706/7175/9631/6428/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/10189/8086/9972/8021/6396/129401/55746/8480 30 African_swine_fever_virus R-HSA-69186 Lagging Strand Synthesis 14/1415 20/10654 8.877726689565938e-9 3.526122069511971e-8 1.492275769200064e-8 6118/2237/1763/57804/3978/5557/5422/5425/5111/5985/5984/5983/6117/5981 14 African_swine_fever_virus R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 32/1415 84/10654 9.151534354490657e-9 3.6235514531332166e-8 1.533508462090417e-8 6517/7124/1052/1019/8841/4790/5468/892/1051/6720/3952/5465/1050/5970/9612/1024/9314/1387/6907/9439/2033/9443/6256/896/10498/4023/9370/23054/7040/51586/8202/10891 32 African_swine_fever_virus R-HSA-8856688 Golgi-to-ER retrograde transport 43/1415 133/10654 9.902363282546112e-9 3.908665755315561e-8 1.6541705254596484e-8 5321/11258/1783/9585/10382/29127/5861/3832/7277/10671/1780/5048/1781/8398/8655/285643/10121/3796/81876/9183/11316/10112/1062/7846/56992/8729/10376/51143/1314/10540/11004/3835/55083/3833/10383/24137/84643/9493/81930/140735/829/22931/1778 43 African_swine_fever_virus R-HSA-1980143 Signaling by NOTCH1 29/1415 73/10654 1.4936071148866436e-8 5.8773208762257714e-8 2.487317046462685e-8 8454/8841/142678/2648/892/6500/409/3091/10013/7316/9978/9612/1024/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/7088/6868/6233/7311/4851/7314 29 African_swine_fever_virus R-HSA-2468052 Establishment of Sister Chromatid Cohesion 10/1415 11/10654 1.6080723109054276e-8 6.269508917671161e-8 2.653293351219482e-8 10274/23244/10735/23047/5885/8243/9126/114799/113130/157570 10 African_swine_fever_virus R-HSA-2514853 Condensation of Prometaphase Chromosomes 10/1415 11/10654 1.6080723109054276e-8 6.269508917671161e-8 2.653293351219482e-8 64151/1459/9133/10051/891/1457/983/23397/9918/10592 10 African_swine_fever_virus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 10/1415 11/10654 1.6080723109054276e-8 6.269508917671161e-8 2.653293351219482e-8 6885/23118/7098/7316/10454/7189/6233/7311/7314/257397 10 African_swine_fever_virus R-HSA-2559585 Oncogene Induced Senescence 18/1415 33/10654 2.136949594259787e-8 8.280679677756675e-8 3.5044327428329633e-8 1019/1029/7027/5594/5925/7316/1869/6667/4194/1021/7157/23112/6233/7311/26523/7314/5595/4193 18 African_swine_fever_virus R-HSA-389356 CD28 co-stimulation 18/1415 33/10654 2.136949594259787e-8 8.280679677756675e-8 3.5044327428329633e-8 5295/5170/1326/5290/207/941/57761/9020/6714/4067/2534/998/942/2475/3932/5058/940/5879 18 African_swine_fever_virus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 17/1415 30/10654 2.458261264934388e-8 9.468030508277597e-8 4.006926655124314e-8 6118/57804/7316/9978/5425/5111/5427/5985/5984/6233/7311/5983/6117/5981/7314/51514/8451 17 African_swine_fever_virus R-HSA-114452 Activation of BH3-only proteins 17/1415 30/10654 2.458261264934388e-8 9.468030508277597e-8 4.006926655124314e-8 596/7531/7027/7532/207/10971/7533/2810/1869/8655/7157/8626/7161/5599/7159/637/140735 17 African_swine_fever_virus R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 15/1415 24/10654 2.651366008792324e-8 1.018092506699409e-7 4.3086278597324784e-8 6118/2237/1763/57804/3978/5557/5422/5425/5111/5427/5985/5984/5983/6117/5981 15 African_swine_fever_virus R-HSA-110312 Translesion synthesis by REV1 12/1415 16/10654 3.134927180351982e-8 1.2001483271769184e-7 5.079098887634315e-8 6118/7316/5111/51455/5985/5984/6233/7311/5983/6117/5981/7314 12 African_swine_fever_virus R-HSA-451927 Interleukin-2 family signaling 21/1415 44/10654 3.190848179303956e-8 1.217888299067666e-7 5.154175500630068e-8 5295/5777/3562/5290/1437/3578/6775/84868/6774/6850/3718/6772/3567/3558/3717/3563/3716/3932/3600/3559/59067 21 African_swine_fever_virus R-HSA-5685942 HDR through Homologous Recombination (HRR) 27/1415 67/10654 3.267131225618761e-8 1.2432705951381572e-7 5.26159488273302e-8 6118/5888/9156/1763/57804/675/545/472/580/7316/5425/641/5111/10635/10524/5427/5985/1111/5984/6233/672/5932/7311/5983/6117/5981/7314 27 African_swine_fever_virus R-HSA-5693538 Homology Directed Repair 43/1415 138/10654 3.374387534632994e-8 1.2802527034383686e-7 5.418105358043865e-8 1017/6118/25/2237/5888/9156/1763/57804/51720/675/63967/5531/51548/545/472/580/7316/890/5425/641/5111/10635/7341/10524/5427/5985/142/1111/8900/5984/7329/6233/672/5932/7158/7311/6047/9025/5983/6117/7334/5981/7314 43 African_swine_fever_virus R-HSA-72202 Transport of Mature Transcript to Cytoplasm 31/1415 84/10654 3.725536161862584e-8 1.4092727564664715e-7 5.964125873157207e-8 10921/23165/5903/6432/6431/55706/7175/9631/7884/6428/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/10189/8086/9972/8021/6396/129401/55746/8480 31 African_swine_fever_virus R-HSA-5696398 Nucleotide Excision Repair 37/1415 111/10654 4.287303109420766e-8 1.6169620926034996e-7 6.843079459359711e-8 6118/902/5430/57804/3978/7316/9978/85015/4331/5425/5111/7341/10401/5427/5985/2033/142/2068/10987/5984/1069/7329/6233/2873/7311/6612/60/8533/5983/6117/7334/5981/7874/1022/50813/7314/8451 37 African_swine_fever_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 13/1415 19/10654 4.735357098557976e-8 1.7754096968339786e-7 7.513639116171793e-8 5295/4893/5290/7316/1950/3320/6233/7311/1956/3845/3265/11140/7314 13 African_swine_fever_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 13/1415 19/10654 4.735357098557976e-8 1.7754096968339786e-7 7.513639116171793e-8 5295/4893/5290/7316/1950/3320/6233/7311/1956/3845/3265/11140/7314 13 African_swine_fever_virus R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 11/1415 14/10654 5.424244424937285e-8 2.021763831112988e-7 8.556224420876533e-8 2801/5594/5861/9133/891/983/8615/81876/5347/64689/5595 11 African_swine_fever_virus R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 11/1415 14/10654 5.424244424937285e-8 2.021763831112988e-7 8.556224420876533e-8 1017/9134/1027/898/1869/890/1026/7157/8900/144455/79733 11 African_swine_fever_virus R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 14/1415 22/10654 5.64036146374757e-8 2.0900581400650617e-7 8.845249986113268e-8 4000/3725/826/351/994/7531/2801/7001/993/995/6648/4001/5052/1020 14 African_swine_fever_virus R-HSA-8863678 Neurodegenerative Diseases 14/1415 22/10654 5.64036146374757e-8 2.0900581400650617e-7 8.845249986113268e-8 4000/3725/826/351/994/7531/2801/7001/993/995/6648/4001/5052/1020 14 African_swine_fever_virus R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 15/1415 25/10654 5.8143588694290906e-8 2.1482703846059227e-7 9.091607656910237e-8 6118/57804/3978/7316/5425/5111/5427/5985/5984/6233/7311/5983/6117/5981/7314 15 African_swine_fever_virus R-HSA-5693532 DNA Double-Strand Break Repair 48/1415 166/10654 7.561485398006956e-8 2.785695055323722e-7 1.1789226661728619e-7 1017/6118/25/3838/2237/5888/9156/1763/57804/51720/675/63967/5531/51548/545/472/51567/580/5591/7316/890/5425/641/5111/10635/7341/10524/5427/5985/142/1111/7157/8900/5984/7329/6233/672/5932/7158/7311/6047/9025/5983/6117/5599/7334/5981/7314 48 African_swine_fever_virus R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 41/1415 132/10654 7.738789686482804e-8 2.842775055352498e-7 1.203079260661002e-7 1017/6118/25/5888/9156/1763/57804/51720/675/63967/5531/51548/545/472/580/7316/890/5425/641/5111/10635/7341/10524/5427/5985/1111/8900/5984/7329/6233/672/5932/7158/7311/6047/9025/5983/6117/7334/5981/7314 41 African_swine_fever_virus R-HSA-176974 Unwinding of DNA 10/1415 12/10654 8.491845713239736e-8 3.1104138044748426e-7 1.3163455663477947e-7 4172/8318/9837/4173/4174/84515/4171/4175/51659/4176 10 African_swine_fever_virus R-HSA-2871796 FCERI mediated MAPK activation 17/1415 32/10654 8.921799505192024e-8 3.2585078077870867e-7 1.3790198267250832e-7 3725/5601/4893/5594/4214/6850/4067/5602/5609/2353/3845/5599/3265/5058/6416/5879/5595 17 African_swine_fever_virus R-HSA-5655862 Translesion synthesis by POLK 12/1415 17/10654 9.365580469802143e-8 3.401043650605292e-7 1.439341840622224e-7 6118/7316/5111/51455/5985/5984/6233/7311/5983/6117/5981/7314 12 African_swine_fever_virus R-HSA-5656121 Translesion synthesis by POLI 12/1415 17/10654 9.365580469802143e-8 3.401043650605292e-7 1.439341840622224e-7 6118/7316/5111/51455/5985/5984/6233/7311/5983/6117/5981/7314 12 African_swine_fever_virus R-HSA-1227986 Signaling by ERBB2 22/1415 50/10654 9.427479566752037e-8 3.413768241977732e-7 1.444726963145986e-7 5295/4893/5290/10273/207/5578/2069/2064/7316/1950/6714/3320/2534/6233/5580/7311/1956/5581/3845/3265/11140/7314 22 African_swine_fever_virus R-HSA-1236394 Signaling by ERBB4 24/1415 58/10654 1.0373851155306378e-7 3.7457854597711383e-7 1.5852386185291747e-7 5295/4893/5290/2670/5241/2069/23118/51741/348/7316/1950/6714/2099/1447/6868/3925/6285/6233/7311/1956/3845/3265/7314/6387 24 African_swine_fever_virus R-HSA-933541 TRAF6 mediated IRF7 activation 16/1415 29/10654 1.0654482852774494e-7 3.836217480418238e-7 1.6235099859155411e-7 3665/7186/29110/57506/7706/23586/1387/2033/64135/3661/7189/3439/10010/84282/9641/3456 16 African_swine_fever_virus R-HSA-5696395 Formation of Incision Complex in GG-NER 20/1415 43/10654 1.1685435615623403e-7 4.195533521880606e-7 1.7755746653534222e-7 6118/902/7316/9978/85015/4331/7341/10401/142/2068/1069/7329/6233/7311/6612/6117/7334/1022/7314/8451 20 African_swine_fever_virus R-HSA-180024 DARPP-32 events 15/1415 26/10654 1.2056129050241593e-7 4.3164338092555115e-7 1.8267403838913135e-7 5567/5568/5528/5566/5519/5576/5499/5577/5518/808/801/1020/805/5515/5516 15 African_swine_fever_virus R-HSA-9018519 Estrogen-dependent gene expression 44/1415 150/10654 1.671031091510595e-7 5.965956509297658e-7 2.5248281719749086e-7 27161/3725/3838/596/5241/7031/5430/5451/10274/10735/5885/865/1655/6667/7033/2099/4609/2962/8850/10524/1387/3320/2033/8243/9126/595/3065/861/23028/23112/10498/1025/2353/1386/6908/3169/904/3276/7392/26523/8202/10728/2957/6387 44 African_swine_fever_virus R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 11/1415 15/10654 1.788779614695866e-7 6.245985962303423e-7 2.643338297020207e-7 1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 11 African_swine_fever_virus R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 11/1415 15/10654 1.788779614695866e-7 6.245985962303423e-7 2.643338297020207e-7 1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 11 African_swine_fever_virus R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 11/1415 15/10654 1.788779614695866e-7 6.245985962303423e-7 2.643338297020207e-7 1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 11 African_swine_fever_virus R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 11/1415 15/10654 1.788779614695866e-7 6.245985962303423e-7 2.643338297020207e-7 1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 11 African_swine_fever_virus R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 11/1415 15/10654 1.788779614695866e-7 6.245985962303423e-7 2.643338297020207e-7 1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 11 African_swine_fever_virus R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 11/1415 15/10654 1.788779614695866e-7 6.245985962303423e-7 2.643338297020207e-7 1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 11 African_swine_fever_virus R-HSA-937039 IRAK1 recruits IKK complex 11/1415 15/10654 1.788779614695866e-7 6.245985962303423e-7 2.643338297020207e-7 1147/8517/7316/7335/3654/7189/6233/7311/7334/3551/7314 11 African_swine_fever_virus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 11/1415 15/10654 1.788779614695866e-7 6.245985962303423e-7 2.643338297020207e-7 1147/8517/7316/7335/3654/7189/6233/7311/7334/3551/7314 11 African_swine_fever_virus R-HSA-180786 Extension of Telomeres 16/1415 30/10654 2.0021593238877578e-7 6.971902741537918e-7 2.950550582571433e-7 6118/2237/7015/1763/57804/3978/5557/5422/5425/5111/5427/5985/5984/5983/6117/5981 16 African_swine_fever_virus R-HSA-73894 DNA Repair 78/1415 334/10654 2.53279798782275e-7 8.795590826564797e-7 3.7223461943555516e-7 1017/6118/2176/25/3838/2237/902/5888/9156/1763/5430/57804/51720/675/63967/5531/51548/545/472/7706/51567/3978/580/5591/7316/9978/890/85015/4331/5425/641/5111/10635/7415/51455/7341/10524/10401/5427/5985/2033/29089/142/2068/1111/10987/7157/55215/8900/5984/1069/7329/4255/6233/2873/672/5932/7158/7311/6047/9025/2189/6612/60/8533/5983/6117/2175/5599/7334/10973/5981/7874/1022/50813/7314/51514/8451 78 African_swine_fever_virus R-HSA-68884 Mitotic Telophase/Cytokinesis 10/1415 13/10654 3.2391644592157965e-007 1.1187440292563254e-6 4.7345910716798405e-7 10274/23244/10735/23047/5885/10112/8243/9126/5347/9493 10 African_swine_fever_virus R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 10/1415 13/10654 3.2391644592157965e-007 1.1187440292563254e-6 4.7345910716798405e-7 7531/7532/10971/7533/2810/891/983/995/1111/7465 10 African_swine_fever_virus R-HSA-73886 Chromosome Maintenance 35/1415 110/10654 3.5840403464223023e-7 1.2345027859899042e-6 5.224488994499491e-7 6118/55839/79682/2237/55320/7015/1763/1058/401541/79019/57804/80152/4869/79172/23421/55355/64105/3978/5557/5422/5425/5111/55166/2491/5427/5985/1060/91687/5984/387103/11339/5983/6117/5981/64946 35 African_swine_fever_virus R-HSA-166520 Signaling by NTRKs 33/1415 101/10654 3.8741667079838335e-7 1.3308286177966088e-6 5.63214562668489e-7 5295/627/9252/4893/5290/5604/5594/1785/5528/6774/9261/6714/5605/7867/5802/5519/1432/4914/2534/4803/1385/163/5518/1213/3845/5600/3265/1175/1020/5879/5595/5515/5516 33 African_swine_fever_virus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 28/1415 79/10654 4.4839519481704676e-7 1.5361463412734945e-6 6.501062407476548e-7 6118/902/5430/57804/3978/7316/9978/4331/5425/5111/5427/5985/2033/2068/10987/5984/6233/2873/7311/8533/5983/6117/5981/7874/1022/50813/7314/8451 28 African_swine_fever_virus R-HSA-9006936 Signaling by TGF-beta family members 33/1415 102/10654 5.007659294282307e-7 1.7108920082141865e-6 7.240596432129275e-7 5590/892/7027/7321/10273/7323/7316/1875/5501/9612/1024/6667/5933/4609/4089/22938/8812/4088/1874/142/905/3065/5499/6233/7514/1025/7311/7040/904/5500/7314/4221/5054 33 African_swine_fever_virus R-HSA-156711 Polo-like kinase mediated events 11/1415 16/10654 5.034410787349376e-7 1.7108920082141865e-6 7.240596432129275e-7 4605/2305/1063/9133/891/993/9088/2033/995/5347/7465 11 African_swine_fever_virus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 11/1415 16/10654 5.034410787349376e-7 1.7108920082141865e-6 7.240596432129275e-7 6885/23118/7099/7316/3656/10454/7189/6233/7311/7314/257397 11 African_swine_fever_virus R-HSA-1643713 Signaling by EGFR in Cancer 14/1415 25/10654 5.316894505919078e-7 1.7919492284195445e-6 7.58363539461168e-7 5295/4893/5290/2069/7316/1950/3320/6233/7311/1956/3845/3265/11140/7314 14 African_swine_fever_virus R-HSA-3371378 Regulation by c-FLIP 9/1415 11/10654 5.37161806473522e-7 1.7919492284195445e-6 7.58363539461168e-7 7186/8737/355/841/8797/8837/8772/8717/8743 9 African_swine_fever_virus R-HSA-4755510 SUMOylation of immune response proteins 9/1415 11/10654 5.37161806473522e-7 1.7919492284195445e-6 7.58363539461168e-7 8517/5970/4792/7341/10401/7329/6612/9641/4791 9 African_swine_fever_virus R-HSA-5218900 CASP8 activity is inhibited 9/1415 11/10654 5.37161806473522e-7 1.7919492284195445e-6 7.58363539461168e-7 7186/8737/355/841/8797/8837/8772/8717/8743 9 African_swine_fever_virus R-HSA-68689 CDC6 association with the ORC:origin complex 9/1415 11/10654 5.37161806473522e-7 1.7919492284195445e-6 7.58363539461168e-7 5000/23594/1869/84515/4998/990/23595/5001/4999 9 African_swine_fever_virus R-HSA-69416 Dimerization of procaspase-8 9/1415 11/10654 5.37161806473522e-7 1.7919492284195445e-6 7.58363539461168e-7 7186/8737/355/841/8797/8837/8772/8717/8743 9 African_swine_fever_virus R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 9/1415 11/10654 5.37161806473522e-7 1.7919492284195445e-6 7.58363539461168e-7 6885/23118/7316/10454/7189/6233/7311/7314/257397 9 African_swine_fever_virus R-HSA-389357 CD28 dependent PI3K/Akt signaling 13/1415 22/10654 5.880485368672918e-7 1.9394168241030467e-6 8.207727004154681e-7 5295/5170/1326/5290/207/941/57761/9020/2534/942/2475/3932/940 13 African_swine_fever_virus R-HSA-5693607 Processing of DNA double-strand break ends 32/1415 98/10654 5.887060017770007e-7 1.9394168241030467e-6 8.207727004154681e-7 1017/6118/9156/1763/51720/63967/5531/51548/545/472/580/7316/890/641/7341/10524/5985/1111/8900/5984/7329/6233/672/5932/7158/7311/6047/9025/5983/6117/7334/7314 32 African_swine_fever_virus R-HSA-110320 Translesion Synthesis by POLH 12/1415 19/10654 5.889967695545052e-7 1.9394168241030467e-6 8.207727004154681e-7 6118/7316/5111/7415/5985/5984/6233/7311/5983/6117/5981/7314 12 African_swine_fever_virus R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 12/1415 19/10654 5.889967695545052e-7 1.9394168241030467e-6 8.207727004154681e-7 7027/7153/5934/1869/1875/993/5933/5111/4609/990/1874/3065 12 African_swine_fever_virus R-HSA-6804760 Regulation of TP53 Activity through Methylation 12/1415 19/10654 5.889967695545052e-7 1.9394168241030467e-6 8.207727004154681e-7 472/79813/7316/4194/2033/7157/6233/7311/10419/10919/7314/4193 12 African_swine_fever_virus R-HSA-187037 Signaling by NTRK1 (TRKA) 28/1415 80/10654 6.034844329762268e-7 1.9819863418934996e-6 8.38788372775335e-7 5295/9252/4893/5290/5604/5594/1785/5528/6774/9261/6714/5605/7867/5519/1432/4914/4803/1385/163/5518/1213/3845/5600/3265/1175/5595/5515/5516 28 African_swine_fever_virus R-HSA-5626467 RHO GTPases activate IQGAPs 16/1415 32/10654 6.365587240622293e-7 2.079861538002811e-6 8.802097361542395e-7 6249/1499/10382/7277/7846/999/10376/998/10788/10383/60/808/801/5879/4221/805 16 African_swine_fever_virus R-HSA-5656169 Termination of translesion DNA synthesis 16/1415 32/10654 6.365587240622293e-7 2.079861538002811e-6 8.802097361542395e-7 6118/57804/7706/7316/5425/5111/51455/5427/5985/5984/6233/7311/5983/6117/5981/7314 16 African_swine_fever_virus R-HSA-1433557 Signaling by SCF-KIT 19/1415 43/10654 6.549158848500383e-7 2.1343540760112788e-6 9.032713013721177e-7 5295/5777/4893/5290/5578/4318/9306/6774/6772/6714/8651/4067/3717/2534/1111/3932/3845/3265/5879 19 African_swine_fever_virus R-HSA-380108 Chemokine receptors bind chemokines 23/1415 59/10654 6.873618005116728e-7 2.2343653413052077e-6 9.455966618965267e-7 7852/3579/6351/2919/3577/3576/2920/2921/1236/6352/6376/6348/6354/3627/6364/10563/9034/4283/2833/6347/6356/1234/6387 23 African_swine_fever_virus R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 21/1415 51/10654 7.165582737641095e-7 2.3233305253933243e-6 9.832472553530075e-7 5321/11258/1783/10382/7277/10671/1780/5048/1781/8398/8655/10121/7846/10376/51143/10540/10383/140735/829/22931/1778 21 African_swine_fever_virus R-HSA-983231 Factors involved in megakaryocyte development and platelet production 46/1415 168/10654 7.964048309517608e-7 2.575650229363074e-6 1.090030450291549e-6 1017/25/2624/5868/5567/9585/10382/5568/29127/3832/7277/285643/3659/5566/3796/10112/1062/3717/7846/5576/56992/10376/3066/3065/998/7157/7975/23028/3439/11004/5577/3835/55083/3833/10383/24137/60/84643/9493/7465/3456/1020/81930/3660/829/5879 46 African_swine_fever_virus R-HSA-5218920 VEGFR2 mediated vascular permeability 15/1415 29/10654 8.174415989016405e-7 2.6369753101623986e-6 1.1159835881344868e-6 5170/857/1499/207/57761/1003/3320/4846/3728/2475/808/5058/801/5879/805 15 African_swine_fever_virus R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 10/1415 14/10654 9.981014501021026e-7 3.1714673576994312e-6 1.3421837921109856e-6 5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 10 African_swine_fever_virus R-HSA-4839744 truncated APC mutants destabilize the destruction complex 10/1415 14/10654 9.981014501021026e-7 3.1714673576994312e-6 1.3421837921109856e-6 5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 10 African_swine_fever_virus R-HSA-4839748 AMER1 mutants destabilize the destruction complex 10/1415 14/10654 9.981014501021026e-7 3.1714673576994312e-6 1.3421837921109856e-6 5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 10 African_swine_fever_virus R-HSA-5467337 APC truncation mutants have impaired AXIN binding 10/1415 14/10654 9.981014501021026e-7 3.1714673576994312e-6 1.3421837921109856e-6 5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 10 African_swine_fever_virus R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 10/1415 14/10654 9.981014501021026e-7 3.1714673576994312e-6 1.3421837921109856e-6 5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 10 African_swine_fever_virus R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 10/1415 14/10654 9.981014501021026e-7 3.1714673576994312e-6 1.3421837921109856e-6 5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 10 African_swine_fever_virus R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 49/1415 185/10654 1.026807908567883e-6 3.254545765061794e-6 1.3773430667494114e-6 6158/6138/2091/9349/4736/6206/6194/6191/6128/6129/6222/1454/6176/6136/6125/6224/6146/51065/6154/6202/6232/55781/6164/6155/6218/6229/6231/6130/6204/6228/23521/6235/6181/6124/6207/10969/6139/6233/7311/6223/6188/6135/1453/4691/6137/6170/6122/6133/6230 49 African_swine_fever_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 20/1415 48/10654 1.0500337290626425e-6 3.3116448378129493e-6 1.4015077329267607e-6 5295/5777/3562/5290/1437/7316/6850/3718/5566/3567/3558/4067/3717/2534/3563/6233/3716/7311/3559/7314 20 African_swine_fever_virus R-HSA-73893 DNA Damage Bypass 20/1415 48/10654 1.0500337290626425e-6 3.3116448378129493e-6 1.4015077329267607e-6 6118/57804/7706/7316/9978/5425/5111/7415/51455/5427/5985/5984/6233/7311/5983/6117/5981/7314/51514/8451 20 African_swine_fever_virus R-HSA-2559580 Oxidative Stress Induced Senescence 37/1415 125/10654 1.2416522719382318e-6 3.906287221865081e-6 1.6531639159990529e-6 3725/1019/5601/5606/9448/1029/7027/2146/6045/5594/7295/7316/1869/9261/7867/4194/1432/5602/23512/1021/7157/23112/5609/6233/2353/7311/5599/5600/4217/26523/3456/6416/5608/7314/5595/4193/23043 37 African_swine_fever_virus R-HSA-196299 Beta-catenin phosphorylation cascade 11/1415 17/10654 1.254714081135945e-6 3.918284022417165e-6 1.6582410331319486e-6 1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 11 African_swine_fever_virus R-HSA-8934593 Regulation of RUNX1 Expression and Activity 11/1415 17/10654 1.254714081135945e-6 3.918284022417165e-6 1.6582410331319486e-6 27161/894/865/6714/1021/595/861/896/5371/23112/26523 11 African_swine_fever_virus R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 11/1415 17/10654 1.254714081135945e-6 3.918284022417165e-6 1.6582410331319486e-6 6885/23118/7099/7316/3656/10454/7189/6233/7311/7314/257397 11 African_swine_fever_virus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 24/1415 65/10654 1.264298034280953e-6 3.938536278360518e-6 1.6668119079400594e-6 6118/902/5430/57804/3978/7316/9978/4331/5425/5111/5427/5985/2033/2068/5984/6233/7311/5983/6117/5981/7874/1022/7314/8451 24 African_swine_fever_virus R-HSA-5696400 Dual Incision in GG-NER 18/1415 41/10654 1.4491681851923903e-6 4.503405289436499e-6 1.9058678230171445e-6 6118/57804/7316/9978/5425/5111/5427/5985/142/2068/5984/6233/7311/5983/6117/5981/7314/8451 18 African_swine_fever_virus R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 18/1415 42/10654 2.223168498446521e-6 6.891822345184215e-6 2.9166600839696335e-6 6118/5888/9156/1763/675/545/472/580/641/10635/10524/5985/1111/5984/672/5932/5983/6117 18 African_swine_fever_virus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 13/1415 24/10654 2.277148423210369e-6 7.041984539903598e-6 2.9802096152144926e-6 596/207/5594/2069/6722/1027/1950/595/7514/1385/2353/1956/5595 13 African_swine_fever_virus R-HSA-2132295 MHC class II antigen presentation 36/1415 123/10654 2.3099929307816665e-006 7.126216055882277e-6 3.015856892257107e-6 164/11258/1783/10382/29127/1785/3832/7277/10671/1780/1781/8655/285643/10121/3796/10112/1062/7846/56992/10376/51143/10540/11004/3835/163/1213/10383/24137/84643/9493/6396/1175/81930/140735/829/1778 36 African_swine_fever_virus R-HSA-2162123 Synthesis of Prostaglandins (PG) and Thromboxanes (TX) 10/1415 15/10654 2.636548427367137e-6 8.094331041506354e-6 3.4255688949519624e-6 5730/3248/5743/5740/9536/80142/27306/6916/5742/10728 10 African_swine_fever_virus R-HSA-69183 Processive synthesis on the lagging strand 10/1415 15/10654 2.636548427367137e-6 8.094331041506354e-6 3.4255688949519624e-6 6118/2237/1763/57804/3978/5557/5422/5425/5111/6117 10 African_swine_fever_virus R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 12/1415 21/10654 2.654791043779615e-6 8.13069738950335e-6 3.440959349071359e-6 6118/2237/57804/3978/5425/5111/5427/5985/5984/5983/6117/5981 12 African_swine_fever_virus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 11/1415 18/10654 2.8384119783661696e-6 8.672167366594716e-6 3.670112654213342e-6 3665/29110/7099/7316/3661/6233/10010/7311/7187/9641/7314 11 African_swine_fever_virus R-HSA-69473 G2/M DNA damage checkpoint 30/1415 95/10654 2.8845402310878056e-6 8.791967946553001e-6 3.7208129700514164e-6 6118/9156/1763/7531/7532/10971/51720/7533/2810/545/472/580/891/983/641/7341/10524/5985/995/1111/7157/5984/672/5932/7158/9025/5983/6117/7334/7465 30 African_swine_fever_virus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 17/1415 39/10654 3.2051551640569136e-6 9.72255898213923e-6 4.114644614578779e-6 6118/57804/7706/7316/5425/5111/7415/51455/5427/5985/5984/6233/7311/5983/6117/5981/7314 17 African_swine_fever_virus R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 17/1415 39/10654 3.2051551640569136e-6 9.72255898213923e-6 4.114644614578779e-6 6118/5888/9156/1763/675/545/472/580/641/10524/5985/1111/5984/672/5932/5983/6117 17 African_swine_fever_virus R-HSA-2219528 PI3K/AKT Signaling in Cancer 31/1415 101/10654 3.872066294200512e-6 1.1717610142687738e-5 4.9589620960813575e-6 5295/1147/2308/5170/5290/842/207/2069/1027/930/3082/941/2064/1950/1026/6714/2099/2932/2247/29851/5880/2534/5728/942/2475/1385/3932/1956/940/5879/4193 31 African_swine_fever_virus R-HSA-9613829 Chaperone Mediated Autophagy 12/1415 22/10654 5.134882052074406e-6 1.5502221112082116e-5 6.560631900512619e-6 2670/1915/10013/5116/6035/7316/3920/3320/6233/7311/3312/7314 12 African_swine_fever_virus R-HSA-8868773 rRNA processing in the nucleus and cytosol 49/1415 195/10654 5.217688767568139e-6 1.5714887259666124e-5 6.650633475248988e-6 6158/6138/2091/9349/4736/6206/6194/6191/6128/6129/6222/1454/6176/6136/6125/6224/6146/51065/6154/6202/6232/55781/6164/6155/6218/6229/6231/6130/6204/6228/23521/6235/6181/6124/6207/10969/6139/6233/7311/6223/6188/6135/1453/4691/6137/6170/6122/6133/6230 49 African_swine_fever_virus R-HSA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 9/1415 13/10654 5.42633652379137e-6 1.622793816879725e-5 6.8677596623093255e-6 7027/5925/5557/5422/1869/5519/5518/5515/5516 9 African_swine_fever_virus R-HSA-5210891 Uptake and function of anthrax toxins 9/1415 13/10654 5.42633652379137e-6 1.622793816879725e-5 6.8677596623093255e-6 5606/5604/5605/5609/808/801/6416/5608/805 9 African_swine_fever_virus R-HSA-879415 Advanced glycosylation endproduct receptor signaling 9/1415 13/10654 5.42633652379137e-6 1.622793816879725e-5 6.8677596623093255e-6 351/6283/5594/177/3146/6288/6285/829/5595 9 African_swine_fever_virus R-HSA-447115 Interleukin-12 family signaling 21/1415 57/10654 6.031053342938444e-6 1.799405821332104e-5 7.615192137982568e-6 3593/6775/3185/6774/6772/149233/6950/3717/3458/3181/998/6648/4001/3716/3594/552900/51561/7297/5721/3586/829 21 African_swine_fever_virus R-HSA-1295596 Spry regulation of FGF signaling 10/1415 16/10654 6.191727341754116e-6 1.8344255131397392e-5 7.763397550328434e-6 5594/7316/6714/6233/7311/5518/7314/5595/5515/5516 10 African_swine_fever_virus R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 10/1415 16/10654 6.191727341754116e-6 1.8344255131397392e-5 7.763397550328434e-6 4605/7027/5934/1869/1875/890/983/5933/1874/3065 10 African_swine_fever_virus R-HSA-205043 NRIF signals cell death from the nucleus 10/1415 16/10654 6.191727341754116e-6 1.8344255131397392e-5 7.763397550328434e-6 4804/8878/23421/7316/4803/7189/6233/7311/5599/7314 10 African_swine_fever_virus R-HSA-6782135 Dual incision in TC-NER 23/1415 66/10654 6.555440392736082e-6 1.9376662184110607e-5 8.200318337057865e-6 6118/902/5430/57804/7316/9978/4331/5425/5111/5427/5985/2033/2068/5984/6233/7311/5983/6117/5981/7874/1022/7314/8451 23 African_swine_fever_virus R-HSA-5685938 HDR through Single Strand Annealing (SSA) 16/1415 37/10654 7.085138398429286e-6 2.0893760799080332e-5 8.842363467083565e-6 6118/25/5888/9156/1763/545/472/580/641/10524/5985/5984/672/5932/5983/6117 16 African_swine_fever_virus R-HSA-110373 Resolution of AP sites via the multiple-nucleotide patch replacement pathway 13/1415 26/10654 7.3247856497311e-6 2.155046889075979e-5 9.120286225664212e-6 6118/2237/57804/3978/5425/5111/5427/5985/142/5984/5983/6117/5981 13 African_swine_fever_virus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 14/1415 30/10654 9.054166125043267e-6 2.6577009572586586e-5 1.1247548048856472e-5 90268/11065/7321/7316/7322/29089/7328/7324/6233/7311/7874/7332/997/7314 14 African_swine_fever_virus R-HSA-438064 Post NMDA receptor activation events 26/1415 81/10654 9.380429880403213e-6 2.7471258935466552e-5 1.1625999681993796e-5 5923/5170/3838/4893/5567/10382/5594/5568/7277/6714/5566/5571/7846/5576/10376/4137/5577/1385/10383/808/3845/3265/801/5879/5595/805 26 African_swine_fever_virus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 24/1415 72/10654 9.974324420218669e-6 2.9143370892179147e-5 1.2333647377451278e-5 6517/7531/4627/7532/207/10971/10382/7533/2810/4644/7277/8766/4641/5571/7846/10376/4012/10383/60/808/801/4218/5879/805 24 African_swine_fever_virus R-HSA-72312 rRNA processing 50/1415 205/10654 1.0267393454543441e-5 2.9930864864047508e-5 1.2666919496068806e-5 6158/6138/2091/9349/4736/6206/6194/6191/6128/6129/3028/6222/1454/6176/6136/6125/6224/6146/51065/6154/6202/6232/55781/6164/6155/6218/6229/6231/6130/6204/6228/23521/6235/6181/6124/6207/10969/6139/6233/7311/6223/6188/6135/1453/4691/6137/6170/6122/6133/6230 50 African_swine_fever_virus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 16/1415 38/10654 1.0738547302789705e-5 3.123270851680941e-5 1.3217867449658052e-5 7020/4605/7422/4869/51741/2064/348/1026/2099/4609/7341/1387/2033/7329/29028/1956 16 African_swine_fever_virus R-HSA-174414 Processive synthesis on the C-strand of the telomere 8/1415 11/10654 1.0799903740455599e-5 3.1339446698901975e-5 1.326303968126126e-5 6118/2237/1763/57804/3978/5425/5111/6117 8 African_swine_fever_virus R-HSA-983189 Kinesins 21/1415 59/10654 1.126781599565611e-5 3.26227656730727e-5 1.3806147881022115e-5 9585/10382/29127/3832/7277/285643/3796/10112/1062/7846/56992/10376/11004/3835/55083/3833/10383/24137/84643/9493/81930 21 African_swine_fever_virus R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 10/1415 17/10654 1.3244603428351509e-5 3.817890117337469e-5 1.6157537371812058e-5 7186/8737/355/841/7099/8797/8837/8772/8717/8743 10 African_swine_fever_virus R-HSA-174411 Polymerase switching on the C-strand of the telomere 9/1415 14/10654 1.339715965643203e-5 3.817890117337469e-5 1.6157537371812058e-5 57804/5557/5422/5425/5111/5985/5984/5983/5981 9 African_swine_fever_virus R-HSA-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase 9/1415 14/10654 1.339715965643203e-5 3.817890117337469e-5 1.6157537371812058e-5 5567/5568/5566/5576/5577/1385/808/801/805 9 African_swine_fever_virus R-HSA-69091 Polymerase switching 9/1415 14/10654 1.339715965643203e-5 3.817890117337469e-5 1.6157537371812058e-5 57804/5557/5422/5425/5111/5985/5984/5983/5981 9 African_swine_fever_virus R-HSA-69109 Leading Strand Synthesis 9/1415 14/10654 1.339715965643203e-5 3.817890117337469e-5 1.6157537371812058e-5 57804/5557/5422/5425/5111/5985/5984/5983/5981 9 African_swine_fever_virus R-HSA-69166 Removal of the Flap Intermediate 9/1415 14/10654 1.339715965643203e-5 3.817890117337469e-5 1.6157537371812058e-5 6118/2237/1763/57804/5557/5422/5425/5111/6117 9 African_swine_fever_virus R-HSA-877312 Regulation of IFNG signaling 9/1415 14/10654 1.339715965643203e-5 3.817890117337469e-5 1.6157537371812058e-5 5777/5770/9021/6772/8651/7341/3717/3458/3716 9 African_swine_fever_virus R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 19/1415 51/10654 1.3806092517624444e-5 3.925624964183595e-5 1.6613477632182013e-5 6206/6194/6191/6222/6224/51065/6202/6232/6218/6229/6231/6204/6228/6235/6207/6233/6223/6188/6230 19 African_swine_fever_virus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 18/1415 47/10654 1.4881055895475504e-5 4.193752115997642e-5 1.7748207638202784e-5 4893/5604/5594/409/6714/5605/3717/2335/3690/5894/60/808/3845/3265/801/5245/5595/805 18 African_swine_fever_virus R-HSA-6802949 Signaling by RAS mutants 18/1415 47/10654 1.4881055895475504e-5 4.193752115997642e-5 1.7748207638202784e-5 4893/5604/5594/409/6714/5605/3717/2335/3690/5894/60/808/3845/3265/801/5245/5595/805 18 African_swine_fever_virus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 18/1415 47/10654 1.4881055895475504e-5 4.193752115997642e-5 1.7748207638202784e-5 4893/5604/5594/409/6714/5605/3717/2335/3690/5894/60/808/3845/3265/801/5245/5595/805 18 African_swine_fever_virus R-HSA-9649948 Signaling downstream of RAS mutants 18/1415 47/10654 1.4881055895475504e-5 4.193752115997642e-5 1.7748207638202784e-5 4893/5604/5594/409/6714/5605/3717/2335/3690/5894/60/808/3845/3265/801/5245/5595/805 18 African_swine_fever_virus R-HSA-5627123 RHO GTPases activate PAKs 12/1415 24/10654 1.6603887281973968e-5 4.658618263882762e-5 1.9715548741927962e-5 4627/4771/10627/4637/79784/998/808/5058/801/5500/5879/805 12 African_swine_fever_virus R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 12/1415 24/10654 1.6603887281973968e-5 4.658618263882762e-5 1.9715548741927962e-5 5590/653361/5579/5578/5594/1432/5880/5580/5300/5600/5879/5595 12 African_swine_fever_virus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 22/1415 65/10654 1.7635394192240054e-5 4.937133484215222e-5 2.0894241669915765e-5 2176/3725/8621/902/5430/545/472/4331/2962/8812/51755/905/2068/1111/7157/55215/672/1025/2353/1386/904/1022 22 African_swine_fever_virus R-HSA-75153 Apoptotic execution phase 19/1415 52/10654 1.9072710120403808e-5 5.327783420446866e-5 2.2547495365011793e-5 4000/3837/1499/10059/63967/841/7082/5339/3146/329/1832/999/836/4137/4001/3836/5580/6093/3148 19 African_swine_fever_virus R-HSA-350054 Notch-HLH transcription pathway 13/1415 28/10654 2.036583672781887e-5 5.676530368653023e-5 2.4023413129998714e-5 8841/2648/10013/4854/9612/10014/22938/8850/1387/6907/3066/3065/4851 13 African_swine_fever_virus R-HSA-445144 Signal transduction by L1 11/1415 21/10654 2.1437417604462253e-5 5.962135180584579e-5 2.523210963003619e-5 5604/1459/5594/8829/1457/5605/3690/1956/5058/5879/5595 11 African_swine_fever_virus R-HSA-5654741 Signaling by FGFR3 16/1415 40/10654 2.3372812233699372e-5 6.486210556557183e-5 2.7450027698047303e-5 5295/4893/5290/5594/7316/6714/2247/6233/7311/5518/3845/3265/7314/5595/5515/5516 16 African_swine_fever_virus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 12/1415 25/10654 2.808311033282954e-5 7.776390682576546e-5 3.291014649713541e-5 9252/5594/5528/9261/5519/1432/1385/5518/5600/5595/5515/5516 12 African_swine_fever_virus R-HSA-3371511 HSF1 activation 8/1415 12/10654 2.8611927512373147e-5 7.854375781474357e-5 3.324018406007203e-5 6118/7531/1915/10013/7415/3320/6117/10728 8 African_swine_fever_virus R-HSA-389359 CD28 dependent Vav1 pathway 8/1415 12/10654 2.8611927512373147e-5 7.854375781474357e-5 3.324018406007203e-5 941/2534/998/942/3932/5058/940/5879 8 African_swine_fever_virus R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 8/1415 12/10654 2.8611927512373147e-5 7.854375781474357e-5 3.324018406007203e-5 834/835/55367/472/8738/7157/8626/7161 8 African_swine_fever_virus R-HSA-9634600 Regulation of glycolysis by fructose 2,6-bisphosphate metabolism 8/1415 12/10654 2.8611927512373147e-5 7.854375781474357e-5 3.324018406007203e-5 5567/5568/5528/5566/5519/5518/5515/5516 8 African_swine_fever_virus R-HSA-4419969 Depolymerisation of the Nuclear Lamina 9/1415 15/10654 2.9538076500029473e-5 8.056415285737652e-5 3.409522722275822e-5 4000/5579/5578/891/983/9663/64900/4001/23175 9 African_swine_fever_virus R-HSA-5637810 Constitutive Signaling by EGFRvIII 9/1415 15/10654 2.9538076500029473e-5 8.056415285737652e-5 3.409522722275822e-5 5295/4893/5290/1950/3320/1956/3845/3265/11140 9 African_swine_fever_virus R-HSA-5637812 Signaling by EGFRvIII in Cancer 9/1415 15/10654 2.9538076500029473e-5 8.056415285737652e-5 3.409522722275822e-5 5295/4893/5290/1950/3320/1956/3845/3265/11140 9 African_swine_fever_virus R-HSA-72649 Translation initiation complex formation 20/1415 58/10654 3.095525511200119e-5 8.424867076521095e-5 3.565453705000025e-5 6206/6194/6191/6222/6224/51065/26986/6202/6232/6218/6229/6231/6204/6228/6235/6207/6233/6223/6188/6230 20 African_swine_fever_virus R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 13/1415 29/10654 3.244562907685012e-5 8.81162276852062e-5 3.7291310072583026e-5 2308/4287/6720/847/4089/4088/2908/3630/3066/3065/6648/56729/10891 13 African_swine_fever_virus R-HSA-5654743 Signaling by FGFR4 16/1415 41/10654 3.3643388052982634e-5 9.117429896661178e-5 3.858550397278448e-5 5295/4893/5290/5594/7316/6714/2247/6233/7311/5518/3845/3265/7314/5595/5515/5516 16 African_swine_fever_virus R-HSA-9022692 Regulation of MECP2 expression and activity 14/1415 33/10654 3.455354610874794e-5 9.344161086003962e-5 3.95450438109075e-5 27161/8841/9212/9612/5566/6907/3066/3065/23112/1385/808/26523/801/805 14 African_swine_fever_virus R-HSA-193704 p75 NTR receptor-mediated signalling 28/1415 97/10654 3.954648605489928e-5 1.0671673837744584e-4 4.5163156495817486e-5 4804/8841/4790/5584/7531/835/8878/1894/23421/4615/7316/5970/4792/836/4803/3066/3065/3654/7189/6868/6233/7311/6610/26574/5599/3551/7314/5879 28 African_swine_fever_virus R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 20/1415 59/10654 4.1051377735767846e-5 1.1054301080966298e-4 4.678245767836167e-5 6206/6194/6191/6222/6224/51065/26986/6202/6232/6218/6229/6231/6204/6228/6235/6207/6233/6223/6188/6230 20 African_swine_fever_virus R-HSA-442755 Activation of NMDA receptors and postsynaptic events 27/1415 93/10654 4.8348598674601963e-005 1.299176932672708e-4 5.498193818342406e-5 5923/5170/3838/8573/4893/5567/10382/5594/5568/7277/6714/5566/5571/7846/5576/10376/4137/5577/1385/10383/808/3845/3265/801/5879/5595/805 27 African_swine_fever_virus R-HSA-4090294 SUMOylation of intracellular receptors 13/1415 30/10654 5.033321839293731e-5 1.3478239145869886e-4 5.704070730497753e-5 5241/5468/5465/2099/7341/10401/2908/6256/7329/367/6612/7421/10062 13 African_swine_fever_virus R-HSA-909733 Interferon alpha/beta signaling 22/1415 69/10654 5.0371074699356383e-5 1.3478239145869886e-4 5.704070730497753e-5 3665/5777/10379/5770/9021/3662/3394/3663/3664/6772/8651/3659/1958/25939/3661/3439/4599/3716/3456/7297/5696/3660 22 African_swine_fever_virus R-HSA-187687 Signalling to ERKs 14/1415 34/10654 5.160943480311048e-5 1.3780586477889374e-4 5.832025914283383e-5 4893/5604/5594/9261/6714/5605/7867/1432/4914/4803/3845/5600/3265/5595 14 African_swine_fever_virus R-HSA-110056 MAPK3 (ERK1) activation 7/1415 10/10654 5.9759968049473476e-5 1.579104353240765e-4 6.682863261468639e-5 5604/983/3717/3716/7297/3569/5595 7 African_swine_fever_virus R-HSA-174437 Removal of the Flap Intermediate from the C-strand 7/1415 10/10654 5.9759968049473476e-5 1.579104353240765e-4 6.682863261468639e-5 6118/2237/1763/57804/5425/5111/6117 7 African_swine_fever_virus R-HSA-2470946 Cohesin Loading onto Chromatin 7/1415 10/10654 5.9759968049473476e-5 1.579104353240765e-4 6.682863261468639e-5 10274/23244/10735/23047/5885/8243/9126 7 African_swine_fever_virus R-HSA-8877330 RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) 7/1415 10/10654 5.9759968049473476e-5 1.579104353240765e-4 6.682863261468639e-5 865/3558/50943/3458/861/3559/1493 7 African_swine_fever_virus R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 7/1415 10/10654 5.9759968049473476e-5 1.579104353240765e-4 6.682863261468639e-5 2308/7295/8850/1387/10628/2033/23411 7 African_swine_fever_virus R-HSA-9020591 Interleukin-12 signaling 17/1415 47/10654 6.0401474414029444e-5 1.5927442734487847e-4 6.740588212616084e-5 3593/6775/3185/6950/3717/3458/3181/998/6648/4001/3716/3594/552900/7297/5721/3586/829 17 African_swine_fever_virus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 11/1415 23/10654 6.368110218575345e-5 1.6757490865029528e-4 7.09186950352403e-5 7321/7323/7316/9612/4089/4088/142/3065/6233/7311/7314 11 African_swine_fever_virus R-HSA-171007 p38MAPK events 8/1415 13/10654 6.570887309410364e-5 1.7255367293926804e-4 7.302573760566977e-5 4893/9261/6714/7867/1432/3845/5600/3265 8 African_swine_fever_virus R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 12/1415 27/10654 7.26455937793635e-5 1.8998467015138065e-4 8.040263898907245e-5 7186/842/8737/355/841/7099/8797/836/8837/8772/8717/8743 12 African_swine_fever_virus R-HSA-912526 Interleukin receptor SHC signaling 12/1415 27/10654 7.26455937793635e-5 1.8998467015138065e-4 8.040263898907245e-5 5295/5777/3562/5290/1437/3718/3567/3558/3717/3563/3716/3559 12 African_swine_fever_virus R-HSA-5578749 Transcriptional regulation by small RNAs 29/1415 106/10654 8.513817708326793e-5 2.221984046670093e-4 9.403568245876995e-5 23165/27161/5903/55706/7175/9631/5430/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/9972/8021/6396/129401/26523/55746/8480 29 African_swine_fever_virus R-HSA-167044 Signalling to RAS 10/1415 20/10654 8.606353066373856e-5 2.2323826015022794e-4 9.447575546545737e-5 4893/9261/6714/7867/1432/4914/4803/3845/5600/3265 10 African_swine_fever_virus R-HSA-3232118 SUMOylation of transcription factors 10/1415 20/10654 8.606353066373856e-5 2.2323826015022794e-4 9.447575546545737e-5 7020/6670/1029/7341/10401/7157/7329/7158/6612/4193 10 African_swine_fever_virus R-HSA-622312 Inflammasomes 10/1415 20/10654 8.606353066373856e-5 2.2323826015022794e-4 9.447575546545737e-5 834/596/351/4790/7295/5970/598/10628/114548/4791 10 African_swine_fever_virus R-HSA-8986944 Transcriptional Regulation by MECP2 20/1415 62/10654 9.113631490247625e-5 2.3591498216099247e-4 9.984061939150042e-5 27161/627/8841/5770/5468/9212/6657/9612/5566/6907/5728/3066/3065/3654/23112/1385/808/26523/801/805 20 African_swine_fever_virus R-HSA-1989781 PPARA activates gene expression 31/1415 117/10654 9.507234921803574e-5 2.45603568813259e-4 1.0394088671462617e-4 8841/1374/5468/892/51/57761/6720/5465/19/335/9612/1024/6667/336/1387/6907/9439/2033/9443/4199/6256/2168/10498/23054/1579/196/405/51586/8202/10891/10062 31 African_swine_fever_virus R-HSA-982772 Growth hormone receptor signaling 11/1415 24/10654 1.0351566864279742e-4 2.66873052423926e-4 1.1294225830355392e-4 5777/5770/9021/5594/6774/6772/8651/4067/3717/6868/5595 11 African_swine_fever_virus R-HSA-72702 Ribosomal scanning and start codon recognition 19/1415 58/10654 1.0758742941102093e-4 2.7680895299880083e-4 1.171471903452625e-4 6206/6194/6191/6222/6224/51065/6202/6232/6218/6229/6231/6204/6228/6235/6207/6233/6223/6188/6230 19 African_swine_fever_virus R-HSA-9012852 Signaling by NOTCH3 17/1415 49/10654 1.1029817680692379e-4 2.832100661042427e-4 1.1985617936913994e-4 142678/2648/10460/7316/1950/4854/6772/22938/8850/1387/2033/6233/7311/1956/9787/4851/7314 17 African_swine_fever_virus R-HSA-1482922 Acyl chain remodelling of PI 9/1415 17/10654 1.1165379479881176e-4 2.855371693949492e-4 1.2084102328114542e-4 5321/8399/5319/26279/30814/5320/8605/5322/64600 9 African_swine_fever_virus R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 9/1415 17/10654 1.1165379479881176e-4 2.855371693949492e-4 1.2084102328114542e-4 2308/857/1027/5934/1026/4089/1647/9314/4088 9 African_swine_fever_virus R-HSA-1251985 Nuclear signaling by ERBB4 13/1415 32/10654 1.1286184759269989e-4 2.880470045990393e-4 1.2190320042246807e-4 2670/5241/2069/23118/51741/348/6714/2099/1447/6868/3925/6285/6387 13 African_swine_fever_virus R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 31/1415 119/10654 1.335590448305443e-4 3.401874668930297e-4 1.4396935325051817e-4 8841/1374/5468/892/51/57761/6720/5465/19/335/9612/1024/6667/336/1387/6907/9439/2033/9443/4199/6256/2168/10498/23054/1579/196/405/51586/8202/10891/10062 31 African_swine_fever_virus R-HSA-3371568 Attenuation phase 8/1415 14/10654 1.3545782434433204e-4 3.4296194171642633e-4 1.4514352744800522e-4 3303/3305/1387/3320/2033/3306/3312/10728 8 African_swine_fever_virus R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 8/1415 14/10654 1.3545782434433204e-4 3.4296194171642633e-4 1.4514352744800522e-4 8841/9612/5566/6907/3065/808/801/805 8 African_swine_fever_virus R-HSA-9005895 Pervasive developmental disorders 8/1415 14/10654 1.3545782434433204e-4 3.4296194171642633e-4 1.4514352744800522e-4 8841/9612/5566/6907/3065/808/801/805 8 African_swine_fever_virus R-HSA-1059683 Interleukin-6 signaling 7/1415 11/10654 1.4544008059025465e-4 3.675036628831285e-4 0.00015552972937453202 9021/6774/6772/3717/3716/7297/3569 7 African_swine_fever_virus R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic 27/1415 99/10654 1.5624401409957222e-4 3.940201228582466e-4 1.6675165247468965e-4 9585/10382/29127/5861/3832/7277/285643/3796/81876/9183/11316/10112/1062/7846/56992/8729/10376/1314/11004/3835/55083/3833/10383/24137/84643/9493/81930 27 African_swine_fever_virus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 11/1415 25/10654 1.6278410731491476e-4 4.097001988064488e-4 1.7338755359650119e-4 1147/2308/5170/842/207/1027/1026/2932/2475/1385/4193 11 African_swine_fever_virus R-HSA-8852135 Protein ubiquitination 23/1415 79/10654 1.6381817309951387e-4 4.1148794073020184e-4 1.7414413657967882e-4 90268/11065/7321/79139/5591/7323/7316/8915/5111/7415/7322/29089/7328/7324/6233/7311/7334/7874/7332/997/80349/7314/123169 23 African_swine_fever_virus R-HSA-8863795 Downregulation of ERBB2 signaling 12/1415 29/10654 1.6790937567943748e-4 4.209325769005228e-4 1.7814116261225487e-4 10273/207/2069/2064/7316/1950/3320/6233/7311/1956/11140/7314 12 African_swine_fever_virus R-HSA-1368082 RORA activates gene expression 9/1415 18/10654 1.9705524685679137e-4 4.92057404233756e-4 2.0824161129939073e-4 1374/6720/5465/1387/6907/2033/6256/10498/23054 9 African_swine_fever_virus R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 9/1415 18/10654 1.9705524685679137e-4 4.92057404233756e-4 2.0824161129939073e-4 4893/5578/5594/4314/1385/1956/3845/3265/5595 9 African_swine_fever_virus R-HSA-111465 Apoptotic cleavage of cellular proteins 14/1415 38/10654 2.138578204592728e-4 5.308853316479214e-4 2.2467382042493507e-4 4000/1499/63967/841/7082/5339/329/1832/999/836/4137/4001/5580/6093 14 African_swine_fever_virus R-HSA-111996 Ca-dependent events 14/1415 38/10654 2.138578204592728e-4 5.308853316479214e-4 2.2467382042493507e-4 3838/5321/5567/5578/5594/5568/5566/5576/5577/5580/1385/808/801/805 14 African_swine_fever_virus R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 14/1415 38/10654 2.138578204592728e-4 5.308853316479214e-4 2.2467382042493507e-4 6595/6597/1459/6045/6598/6599/865/1457/8289/2033/6605/6602/861/6601 14 African_swine_fever_virus R-HSA-1250196 SHC1 events in ERBB2 signaling 10/1415 22/10654 2.3404336701827284e-4 5.787336954868186e-4 2.449235317352804e-4 4893/5578/2069/2064/1950/5580/1956/5581/3845/3265 10 African_swine_fever_virus R-HSA-198753 ERK/MAPK targets 10/1415 22/10654 2.3404336701827284e-4 5.787336954868186e-4 2.449235317352804e-4 9252/5594/5528/5519/1432/5518/5600/5595/5515/5516 10 African_swine_fever_virus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 24/1415 86/10654 2.436723234789182e-4 6.002083781815989e-4 2.540117447934051e-4 5295/25/5290/4627/4771/5594/4644/8398/6850/10768/4641/6714/4067/3320/2534/998/5580/7454/9844/60/5581/5058/5879/5595 24 African_swine_fever_virus R-HSA-5628897 TP53 Regulates Metabolic Genes 24/1415 86/10654 2.436723234789182e-4 6.002083781815989e-4 2.540117447934051e-4 27161/7531/7532/207/10971/7295/7533/2810/7001/2539/5571/5728/6009/7157/8626/23112/2475/4513/50484/4697/26523/5052/2744/7248 24 African_swine_fever_virus R-HSA-6802957 Oncogenic MAPK signaling 21/1415 71/10654 2.443077654647351e-4 6.006096129703641e-4 2.541815497352736e-4 4000/4893/5604/10142/5594/409/23164/6714/5605/3717/2335/3690/5894/60/808/3845/3265/801/5245/5595/805 21 African_swine_fever_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 11/1415 26/10654 2.4851674863430527e-4 6.086026734377687e-4 2.5756426032274616e-4 10273/7316/5501/4088/5499/6233/7514/7311/7040/5500/7314 11 African_swine_fever_virus R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 11/1415 26/10654 2.4851674863430527e-4 6.086026734377687e-4 2.5756426032274616e-4 5888/9156/1763/675/472/580/641/10635/10524/672/5932 11 African_swine_fever_virus R-HSA-72306 tRNA processing 28/1415 107/10654 2.5517386390930334e-4 6.233707345731759e-4 2.638141913676698e-4 23165/5903/55706/7175/9631/3028/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/9972/8021/6396/129401/55746/8480/54888 28 African_swine_fever_virus R-HSA-111447 Activation of BAD and translocation to mitochondria 8/1415 15/10654 2.565089647378214e-4 6.233707345731759e-4 2.638141913676698e-4 596/7531/7532/207/10971/7533/2810/637 8 African_swine_fever_virus R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 8/1415 15/10654 2.565089647378214e-4 6.233707345731759e-4 2.638141913676698e-4 29110/7316/51428/3661/6233/7311/81030/7314 8 African_swine_fever_virus R-HSA-844456 The NLRP3 inflammasome 8/1415 15/10654 2.565089647378214e-4 6.233707345731759e-4 2.638141913676698e-4 834/351/4790/7295/5970/10628/114548/4791 8 African_swine_fever_virus R-HSA-877300 Interferon gamma signaling 25/1415 92/10654 2.8709795699722354e-4 6.963769147776166e-4 2.9471083974604506e-4 3665/5777/10379/960/5770/7412/9021/3383/7706/3662/3394/3663/3664/6772/8651/3659/7341/3717/3458/3661/5371/5580/3716/4261/3660 25 African_swine_fever_virus R-HSA-6802952 Signaling by BRAF and RAF fusions 20/1415 67/10654 2.976077562425917e-4 7.204942060653982e-4 3.0491742043100623e-4 4000/4893/5604/10142/5594/409/23164/6714/5605/3717/2335/3690/5894/60/808/3845/3265/801/5595/805 20 African_swine_fever_virus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 52/1415 244/10654 3.0546840107487273e-4 7.381185128634282e-4 3.1237613157746643e-4 7536/10921/23165/6635/5903/6432/6431/55706/7175/9631/7884/5430/6428/3184/3178/348995/79023/57122/23636/10762/5093/23511/6625/53371/1655/9343/3185/23279/4927/9688/79902/2962/22938/988/9883/4670/23225/10189/3181/1660/8086/2521/9972/6634/8021/3192/6396/129401/3312/55746/8480/1994 52 African_swine_fever_virus R-HSA-210990 PECAM1 interactions 7/1415 12/10654 3.0899949489928926e-4 7.4523407593358e-4 3.153874800629917e-4 5777/5175/6714/4067/2534/3690/3932 7 African_swine_fever_virus R-HSA-76002 Platelet activation, signaling and aggregation 55/1415 262/10654 3.1000071735688776e-4 7.46232787425387e-4 3.1581014068853594e-4 5295/5170/5777/5099/5590/351/5321/5290/5579/5770/7042/5340/7424/5175/207/7422/5578/5594/409/3082/7277/3827/1950/335/308/6850/7123/6714/1191/1432/3920/6403/197/4067/81/3309/5880/2335/2534/3690/998/5894/5580/3932/3479/5581/7040/808/213/801/7043/5879/5595/805/5054 55 African_swine_fever_virus R-HSA-8953750 Transcriptional Regulation by E2F6 13/1415 35/10654 3.2632296749347e-4 7.840387366431008e-4 3.3180984258116247e-4 5888/7027/2146/8317/6045/79813/1869/23512/1111/672/5932/10919/6241 13 African_swine_fever_virus R-HSA-1482925 Acyl chain remodelling of PG 9/1415 19/10654 3.304568757108013e-4 7.924729981668461e-4 3.353792720719354e-4 5321/8399/5319/26279/50487/30814/5320/5322/64600 9 African_swine_fever_virus R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 15/1415 44/10654 3.4473431636185476e-4 8.251550208962662e-4 3.4921049789058935e-4 834/79370/835/355/55367/472/332/8797/1387/8738/7157/8626/7161/7159/637 15 African_swine_fever_virus R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 12/1415 31/10654 3.5371359649489766e-4 8.450563555357423e-4 3.5763286072198797e-4 857/1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 12 African_swine_fever_virus R-HSA-112409 RAF-independent MAPK1/3 activation 10/1415 23/10654 3.6509126304328697e-4 8.706022426416844e-4 3.684440316285566e-4 5604/5594/983/5605/3717/3716/1843/7297/3569/5595 10 African_swine_fever_virus R-HSA-5654738 Signaling by FGFR2 21/1415 73/10654 3.723088248665417e-4 8.861507797853455e-4 3.7502426474828076e-4 5295/4893/5290/5430/5594/3178/7316/3185/6714/2962/4670/2247/6233/7311/5518/3845/3265/7314/5595/5515/5516 21 African_swine_fever_virus R-HSA-177929 Signaling by EGFR 16/1415 49/10654 3.8610238842959636e-4 9.172638050355458e-4 3.8819148152980575e-4 5295/4893/5290/2069/7316/1950/6714/998/6868/6233/7311/1956/29924/3845/3265/7314 16 African_swine_fever_virus R-HSA-5619102 SLC transporter disorders 26/1415 99/10654 3.932412322312685e-4 9.32480608518549e-4 3.946313229972078e-4 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/6396/129401/213/55746/8480 26 African_swine_fever_virus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 17/1415 54/10654 4.172132936145291e-4 9.87482488238485e-4 4.179084446477004e-4 902/5430/7316/9978/4331/2033/2068/10987/6233/2873/7311/8533/7874/1022/50813/7314/8451 17 African_swine_fever_virus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 13/1415 36/10654 4.4933534444145705e-4 0.0010615338713477545 4.4924742909329795e-4 4893/5604/5594/409/6714/5605/2335/3690/5894/60/3845/3265/5595 13 African_swine_fever_virus R-HSA-1433559 Regulation of KIT signaling 8/1415 16/10654 4.534631183435454e-4 0.0010692980026245755 4.5253325548979926e-4 5777/5578/9306/6714/8651/4067/2534/3932 8 African_swine_fever_virus R-HSA-3899300 SUMOylation of transcription cofactors 15/1415 45/10654 4.544226443223208e-4 0.0010695762609882772 4.526510160793488e-4 6045/4869/1655/9612/7341/1387/10401/10521/1616/2033/7329/115426/6612/6294/10891 15 African_swine_fever_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 12/1415 32/10654 4.982246458362137e-4 0.0011696267804114221 4.949929891840132e-4 10273/7316/5501/4089/4088/5499/6233/7514/7311/7040/5500/7314 12 African_swine_fever_virus R-HSA-5654736 Signaling by FGFR1 16/1415 50/10654 4.987708221738716e-4 0.0011696267804114221 4.949929891840132e-4 5295/4893/5290/5594/7316/6714/2247/6233/7311/5518/3845/3265/7314/5595/5515/5516 16 African_swine_fever_virus R-HSA-5625900 RHO GTPases activate CIT 9/1415 20/10654 5.30415067112943e-4 0.0012400714911076696 5.248056084773856e-4 4627/1027/10627/4637/79784/9055/9928/5500/5879 9 African_swine_fever_virus R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic 44/1415 202/10654 5.307623061861309e-4 0.0012400714911076696 5.248056084773856e-4 5321/11258/1783/9585/10382/29127/5861/3832/7277/10671/1780/5048/1781/8398/8655/285643/10121/3796/81876/9183/11316/10112/1062/7846/56992/8729/10376/51143/1314/10540/11004/3835/55083/3833/10383/24137/84643/9493/81930/140735/829/22931/1523/1778 44 African_swine_fever_virus R-HSA-1482788 Acyl chain remodelling of PC 11/1415 28/10654 5.360928920864688e-4 0.001250227643746609 5.291037524986685e-4 5321/8399/8398/5319/26279/50487/30814/5320/8605/5322/64600 11 African_swine_fever_virus R-HSA-6807878 COPI-mediated anterograde transport 26/1415 101/10654 5.492786369324899e-4 0.0012786321383538364 5.41124703050901e-4 11258/1783/2801/10382/5861/7277/10671/1780/1781/8655/10121/8615/81876/11316/7846/8729/10376/51143/1314/3630/10540/10383/64689/140735/829/1778 26 African_swine_fever_virus R-HSA-8940973 RUNX2 regulates osteoblast differentiation 10/1415 24/10654 5.519309733293519e-4 0.0012824575266939784 5.427436300804364e-4 25/8841/5594/5925/10013/865/6714/367/860/5595 10 African_swine_fever_virus R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 32/1415 134/10654 5.735635149690315e-4 0.0013302905611781734 5.62986853916971e-4 5099/351/5579/7042/5340/7424/5175/7422/5578/3082/7277/3827/1950/335/308/7123/1191/3920/6403/197/81/3309/2335/3690/3479/7040/808/213/801/7043/805/5054 32 African_swine_fever_virus R-HSA-202670 ERKs are inactivated 7/1415 13/10654 5.928385536720055e-4 0.0013650322494875345 5.776897424225682e-4 5594/5528/5519/5518/5595/5515/5516 7 African_swine_fever_virus R-HSA-203615 eNOS activation 7/1415 13/10654 5.928385536720055e-4 0.0013650322494875345 5.776897424225682e-4 857/207/3320/4846/808/801/805 7 African_swine_fever_virus R-HSA-2995383 Initiation of Nuclear Envelope Reformation 7/1415 13/10654 5.928385536720055e-4 0.0013650322494875345 5.776897424225682e-4 4000/7443/8815/5520/4001/5518/5515 7 African_swine_fever_virus R-HSA-2995410 Nuclear Envelope Reassembly 7/1415 13/10654 5.928385536720055e-4 0.0013650322494875345 5.776897424225682e-4 4000/7443/8815/5520/4001/5518/5515 7 African_swine_fever_virus R-HSA-8943724 Regulation of PTEN gene transcription 18/1415 61/10654 6.8506594838233e-4 0.0015745367457394963 6.663532875670899e-4 3725/8841/5468/2146/6045/5594/10014/1958/23512/6009/6615/3066/3065/7157/23028/2475/1386/5595 18 African_swine_fever_virus R-HSA-1489509 DAG and IP3 signaling 14/1415 42/10654 6.9865932003301e-4 0.0016028808587760935 6.783486842805779e-4 3838/5567/5578/5568/10768/5566/5576/5577/5580/1385/5581/808/801/805 14 African_swine_fever_virus R-HSA-9020958 Interleukin-21 signaling 6/1415 10/10654 7.070127131765684e-4 0.0016191228080133667 6.852223735101498e-4 6775/6774/3718/6772/3716/59067 6 African_swine_fever_virus R-HSA-211000 Gene Silencing by RNA 32/1415 136/10654 7.534397076099593e-4 0.0017180865371722014 7.271044105304526e-4 23165/27161/5903/55706/7175/9631/5430/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/3320/5901/8086/23112/9972/8021/6396/129401/26523/143689/55746/8480 32 African_swine_fever_virus R-HSA-202131 Metabolism of nitric oxide: eNOS activation and regulation 8/1415 17/10654 7.572936281610859e-4 0.0017180865371722014 7.271044105304526e-4 857/207/1785/3320/4846/808/801/805 8 African_swine_fever_virus R-HSA-9018677 Biosynthesis of DHA-derived SPMs 8/1415 17/10654 7.572936281610859e-4 0.0017180865371722014 7.271044105304526e-4 1558/3248/246/1559/5743/1571/239/240 8 African_swine_fever_virus R-HSA-5654732 Negative regulation of FGFR3 signaling 11/1415 29/10654 7.610939298907656e-4 0.0017180865371722014 7.271044105304526e-4 5594/7316/6714/2247/6233/7311/5518/7314/5595/5515/5516 11 African_swine_fever_virus R-HSA-167161 HIV Transcription Initiation 15/1415 47/10654 7.650959717068969e-4 0.0017180865371722014 7.271044105304526e-4 6875/902/2959/5430/6878/6872/2960/4331/2962/2068/6880/6908/6882/1022/2957 15 African_swine_fever_virus R-HSA-167162 RNA Polymerase II HIV Promoter Escape 15/1415 47/10654 7.650959717068969e-4 0.0017180865371722014 7.271044105304526e-4 6875/902/2959/5430/6878/6872/2960/4331/2962/2068/6880/6908/6882/1022/2957 15 African_swine_fever_virus R-HSA-437239 Recycling pathway of L1 15/1415 47/10654 7.650959717068969e-4 0.0017180865371722014 7.271044105304526e-4 9252/10382/5594/1785/7277/285643/6714/7846/10376/163/1213/10383/24137/60/1175 15 African_swine_fever_virus R-HSA-73776 RNA Polymerase II Promoter Escape 15/1415 47/10654 7.650959717068969e-4 0.0017180865371722014 7.271044105304526e-4 6875/902/2959/5430/6878/6872/2960/4331/2962/2068/6880/6908/6882/1022/2957 15 African_swine_fever_virus R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 15/1415 47/10654 7.650959717068969e-4 0.0017180865371722014 7.271044105304526e-4 6875/902/2959/5430/6878/6872/2960/4331/2962/2068/6880/6908/6882/1022/2957 15 African_swine_fever_virus R-HSA-75953 RNA Polymerase II Transcription Initiation 15/1415 47/10654 7.650959717068969e-4 0.0017180865371722014 7.271044105304526e-4 6875/902/2959/5430/6878/6872/2960/4331/2962/2068/6880/6908/6882/1022/2957 15 African_swine_fever_virus R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 15/1415 47/10654 7.650959717068969e-4 0.0017180865371722014 7.271044105304526e-4 6875/902/2959/5430/6878/6872/2960/4331/2962/2068/6880/6908/6882/1022/2957 15 African_swine_fever_virus R-HSA-9006115 Signaling by NTRK2 (TRKB) 10/1415 25/10654 8.113622173389741e-4 0.0018187678628533263 7.69713344584082e-4 5295/627/4893/5290/6714/2534/3845/3265/1020/5879 10 African_swine_fever_virus R-HSA-5696394 DNA Damage Recognition in GG-NER 13/1415 38/10654 8.152188716769378e-4 0.0018241957498263872 7.720104585376487e-4 7316/9978/142/10987/1069/6233/2873/7311/60/8533/50813/7314/8451 13 African_swine_fever_virus R-HSA-111931 PKA-mediated phosphorylation of CREB 9/1415 21/10654 8.196154605457956e-4 0.001830810633310556 7.7480991645343e-4 5567/5568/5566/5576/5577/1385/808/801/805 9 African_swine_fever_virus R-HSA-162594 Early Phase of HIV Life Cycle 7/1415 14/10654 0.0010502192829996782 0.0023254855552135734 9.84159276751945e-4 2237/7852/3159/3978/8815/3836/1234 7 African_swine_fever_virus R-HSA-198323 AKT phosphorylates targets in the cytosol 7/1415 14/10654 0.0010502192829996782 0.0023254855552135734 9.84159276751945e-4 1147/842/207/1027/1026/2932/4193 7 African_swine_fever_virus R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 7/1415 14/10654 0.0010502192829996782 0.0023254855552135734 9.84159276751945e-4 6118/9156/57804/3978/5425/5111/6117 7 African_swine_fever_virus R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 7/1415 14/10654 0.0010502192829996782 0.0023254855552135734 9.84159276751945e-4 6118/9156/57804/3978/5425/5111/6117 7 African_swine_fever_virus R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 7/1415 14/10654 0.0010502192829996782 0.0023254855552135734 9.84159276751945e-4 207/54971/10848/7157/8626/7161/7159 7 African_swine_fever_virus R-HSA-1482839 Acyl chain remodelling of PE 11/1415 30/10654 0.0010591362953060418 0.002337087207177047 9.89069164658968e-4 5321/8399/8398/5319/26279/50487/30814/5320/8605/5322/64600 11 African_swine_fever_virus R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 11/1415 30/10654 0.0010591362953060418 0.002337087207177047 9.89069164658968e-4 5923/5170/4893/5594/1385/808/3845/3265/801/5595/805 11 African_swine_fever_virus R-HSA-73933 Resolution of Abasic Sites (AP sites) 13/1415 39/10654 0.0010761900814508444 0.0023706024151196243 0.0010032529994004954 6118/2237/57804/3978/5425/5111/5427/5985/142/5984/5983/6117/5981 13 African_swine_fever_virus R-HSA-912631 Regulation of signaling by CBL 9/1415 22/10654 0.001225011525295622 0.0026937537173888156 0.0011400125467602674 5295/5290/7316/6850/4067/2534/6233/7311/7314 9 African_swine_fever_virus R-HSA-114604 GPVI-mediated activation cascade 12/1415 35/10654 0.0012573767314355022 0.0027601482308368275 0.0011681110985611155 5295/5170/5777/5590/5290/6850/4067/5880/2534/998/3932/5879 12 African_swine_fever_virus R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 17/1415 59/10654 0.0012831158351072056 0.0028117934938297557 0.0011899676801084976 7321/79139/5591/7323/7316/8915/5111/7415/7322/7324/6233/7311/7334/7332/80349/7314/123169 17 African_swine_fever_virus R-HSA-114608 Platelet degranulation 30/1415 129/10654 0.0013244271099720414 0.002897326775859664 0.0012261658722632724 5099/351/7042/5340/7424/5175/7422/3082/7277/3827/1950/335/308/7123/1191/3920/6403/197/81/3309/2335/3690/3479/7040/808/213/801/7043/805/5054 30 African_swine_fever_virus R-HSA-445355 Smooth Muscle Contraction 13/1415 40/10654 0.0014033608651783825 0.003059471114308275 0.0012947863177866815 140465/10627/7168/301/7171/4637/800/7169/808/5058/801/7170/805 13 African_swine_fever_virus R-HSA-5674135 MAP2K and MAPK activation 13/1415 40/10654 0.0014033608651783825 0.003059471114308275 0.0012947863177866815 4893/5604/5594/409/6714/5605/2335/3690/5894/60/3845/3265/5595 13 African_swine_fever_virus R-HSA-5339562 Uptake and actions of bacterial toxins 11/1415 31/10654 0.0014471187796521732 0.0031440819981844647 0.0013305941455731185 5606/5604/1938/5605/3320/5609/808/801/6416/5608/805 11 African_swine_fever_virus R-HSA-5654733 Negative regulation of FGFR4 signaling 11/1415 31/10654 0.0014471187796521732 0.0031440819981844647 0.0013305941455731185 5594/7316/6714/2247/6233/7311/5518/7314/5595/5515/5516 11 African_swine_fever_virus R-HSA-111933 Calmodulin induced events 12/1415 36/10654 0.0016613974249325284 0.0035973358212763947 0.0015224138512337881 3838/5567/5578/5568/5566/5576/5577/5580/1385/808/801/805 12 African_swine_fever_virus R-HSA-111997 CaM pathway 12/1415 36/10654 0.0016613974249325284 0.0035973358212763947 0.0015224138512337881 3838/5567/5578/5568/5566/5576/5577/5580/1385/808/801/805 12 African_swine_fever_virus R-HSA-2691230 Signaling by NOTCH1 HD Domain Mutants in Cancer 7/1415 15/10654 0.0017447158114787978 0.0037585318582873764 0.0015906329699655053 142678/7316/6868/6233/7311/4851/7314 7 African_swine_fever_virus R-HSA-2691232 Constitutive Signaling by NOTCH1 HD Domain Mutants 7/1415 15/10654 0.0017447158114787978 0.0037585318582873764 0.0015906329699655053 142678/7316/6868/6233/7311/4851/7314 7 African_swine_fever_virus R-HSA-5358508 Mismatch Repair 7/1415 15/10654 0.0017447158114787978 0.0037585318582873764 0.0015906329699655053 6118/9156/57804/3978/5425/5111/6117 7 African_swine_fever_virus R-HSA-163615 PKA activation 8/1415 19/10654 0.0018418679386545045 0.003954415793969384 0.0016735322131089113 5567/5568/5566/5576/5577/808/801/805 8 African_swine_fever_virus R-HSA-9018678 Biosynthesis of specialized proresolving mediators (SPMs) 8/1415 19/10654 0.0018418679386545045 0.003954415793969384 0.0016735322131089113 1558/3248/246/1559/5743/1571/239/240 8 African_swine_fever_virus R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 16/1415 56/10654 0.0019427209322725248 0.004159975647953912 0.0017605263622547094 8841/23408/5465/1387/6907/6648/6256/10498/1385/23054/1386/6742/808/801/10891/805 16 African_swine_fever_virus R-HSA-8941326 RUNX2 regulates bone development 11/1415 32/10654 0.001944158564031962 0.004159975647953912 0.0017605263622547094 25/8841/5594/5925/10013/865/6714/4089/367/860/5595 11 African_swine_fever_virus R-HSA-8979227 Triglyceride metabolism 12/1415 37/10654 0.002166312945221483 0.004619771398282727 0.001955114650314691 857/5567/5568/5501/5566/9663/64900/5499/2168/23175/2710/5500 12 African_swine_fever_virus R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 12/1415 37/10654 0.002166312945221483 0.004619771398282727 0.001955114650314691 27161/8841/348/19/9612/6907/2033/23028/6256/23112/26523/10062 12 African_swine_fever_virus R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 13/1415 42/10654 0.0023067544448491426 0.004911029982250017 0.0020783770101699935 8945/1499/207/6657/7316/3065/7088/6233/7514/7311/331/7314/4221 13 Avian_infectious_bronchitis_virus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 295/2292 309/10654 6.746036747036597e-182 8.985720947052748e-179 4.11153187003599e-179 8454/9354/57154/5718/197131/23352/5689/26224/8945/10293/51088/140460/5684/79754/6737/8065/64410/127544/114088/5720/11065/285231/221687/9666/84937/57531/142678/55070/5682/84708/246184/146330/55819/51320/93611/7319/54850/142686/8916/79791/26046/151636/5700/122706/7321/5707/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/8697/7320/5690/26235/10477/9817/10193/148581/9039/223082/92912/154881/5717/140739/25897/9491/23198/6500/6478/150726/390594/10533/81559/143471/144699/5706/140462/5705/26259/57674/10197/53339/154214/7336/200845/79876/26263/64750/51619/6477/9690/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/10213/5709/9604/9978/22888/5695/23304/7317/80196/114907/140456/64718/54926/4008/7335/84861/11059/55236/84085/55958/54620/4734/84078/7337/5714/26272/84676/27252/6468/51444/7704/8651/3093/26118/222235/51433/9861/25831/7322/5715/64219/10489/5711/23327/9867/26249/140458/55905/5701/5688/55336/5687/26270/143279/51465/63893/89122/6502/23291/118424/5685/10616/5683/5698/5708/27246/5692/5686/89910/5713/55521/25898/9903/201456/55294/5699/26190/55008/7328/79654/5710/10422/84727/135892/7428/5702/22954/8453/401036/83737/51529/9040/90933/140461/7324/63891/5719/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/5704/6233/90135/56658/9870/51434/26267/142685/5716/25847/90025/7327/10425/25793/51343/7311/26091/23295/6047/84541/7318/23194/51666/90293/131405/55175/55284/868/54461/9320/80204/136371/26232/29882/57520/26234/127247/27338/7334/92591/5930/11275/5694/55182/84961/4591/23014/29116/26268/92369/115290/7332/90678/51725/140459/5693/5721/5696/997/23608/51676/55585/64320/5691/51132/84261/7325/57542/9820/55658/7314/996/10324/283807/140691/899 295 Avian_infectious_bronchitis_virus R-HSA-983169 Class I MHC mediated antigen processing & presentation 308/2292 371/10654 2.2578434788757705e-147 1.503723756931263e-144 6.880480917205638e-145 8454/9354/57154/1147/5718/197131/23352/5689/26224/8945/10293/51088/140460/5684/79754/6737/8065/64410/127544/114088/5720/11065/285231/221687/9666/84937/57531/142678/55070/5682/84708/246184/146330/55819/51320/93611/7319/54850/142686/8916/79791/26046/151636/5700/122706/7321/5707/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/8697/7320/5690/26235/10477/9817/10193/148581/9039/223082/92912/154881/5717/140739/25897/9491/23198/6500/6478/150726/390594/10533/81559/143471/144699/5706/140462/5705/26259/57674/10333/10197/7099/53339/154214/7336/200845/4615/79876/26263/64750/51619/6477/9690/9554/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/10213/5709/9604/9978/22888/5695/23304/7317/80196/114907/140456/22872/64718/54926/4008/7335/84861/7096/11059/55236/84085/55958/54620/4734/84078/7337/5714/26272/84676/27252/6468/51444/7704/8651/3093/26118/222235/51433/9861/25831/7322/5715/64219/10489/5711/23327/9867/26249/140458/55905/5701/5688/55336/5687/26270/143279/51465/63893/89122/6502/23291/118424/5685/10616/5683/3309/5698/5708/27246/5692/5686/89910/5713/55521/25898/9903/201456/55294/5699/26190/55008/7328/79654/5710/10422/84727/135892/7428/5702/22954/8453/401036/83737/51529/9040/695/90933/140461/7324/63891/5719/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/5704/6233/90135/56658/9870/51434/26267/142685/5716/25847/90025/7327/10425/25793/51343/7311/9871/26091/23295/6047/84541/7318/23194/51666/90293/131405/55175/55284/868/54461/9320/80204/136371/26232/29882/57520/26234/6396/127247/27338/7334/92591/5930/11275/5694/55182/7097/84961/4591/3551/23014/29116/26268/92369/115290/7332/90678/51725/140459/5693/5721/5696/997/23608/51676/55585/64320/5691/51132/84261/7325/57542/9820/55658/7314/996/10324/283807/140691/899 308 Avian_infectious_bronchitis_virus R-HSA-8951664 Neddylation 214/2292 234/10654 2.4549445469750154e-120 1.0899953788569069e-117 4.987413658591347e-118 8454/9318/5718/51397/5689/26224/54165/8945/56995/23412/51088/9655/140460/5684/79754/8065/64410/5720/149951/29099/285231/11091/23363/5682/23038/146330/93611/54850/142686/55884/79791/5700/122706/7321/5707/51665/9616/122769/9021/4738/5690/26235/9817/9039/154881/5717/140739/5929/9491/23198/6500/5931/150726/3091/390594/143471/144699/5706/140462/28952/5705/26259/10197/53339/28991/200845/332/26263/140825/8452/8450/7323/9306/10517/89890/142689/7316/10213/5709/9978/5695/114907/140456/4008/84861/64708/84085/55958/54620/84078/5714/55527/26272/27252/6468/7704/1643/26118/222235/10980/9861/7322/5715/122416/10489/5711/26249/140458/5701/5688/55336/5687/26270/1161/6502/23291/170622/5685/90864/5683/55832/5698/5708/1642/5692/10920/5686/23113/5713/9903/201456/55294/5699/26190/10238/5710/84727/10987/7428/5702/8453/123879/401036/9040/140461/5719/79176/80176/8139/23142/126433/10116/5704/6233/90135/2873/26267/26094/142685/5716/25793/7311/1154/84541/23194/83987/51666/2034/90293/55175/8533/54461/80204/136371/26232/8835/26234/127247/8883/92591/51667/11275/5694/51122/84961/54939/23014/26268/92369/115290/54951/51725/140459/5693/55208/5721/84259/5696/51676/5691/84261/150684/50813/57542/9820/7314/51514/10537/51138/10324/8451/56929/283807/899 214 Avian_infectious_bronchitis_virus R-HSA-3700989 Transcriptional Regulation by TP53 273/2292 365/10654 3.5735777251219227e-109 1.1900013824656002e-106 5.4450039548568245e-107 23368/6884/1017/23774/6875/834/6118/2176/80010/27161/27113/5563/3725/9891/9134/27165/4436/83990/8621/902/83667/1820/64769/7862/9156/3622/57060/5883/1763/7531/1029/7027/1459/25946/79370/7486/9540/5430/10111/5457/8793/9219/6874/8445/7532/207/10971/55240/9997/22974/133383/9212/57690/204851/7832/4849/6878/1027/58484/4869/3486/5982/51422/7249/27327/898/5931/355/7295/4850/7533/2810/55367/1460/6749/4292/11200/545/472/117584/53632/27244/79813/8794/192670/7534/332/580/8550/11073/9337/5934/639/64065/7316/1869/891/6872/28996/116028/890/80196/2539/84289/1457/54971/4331/10769/983/1026/54205/5366/6790/641/5933/124446/5111/25904/1108/1643/8148/8797/246175/5395/29117/4194/6879/9150/84883/9656/5519/112858/6119/1647/147923/5928/3364/5876/1432/143686/5571/10524/10848/1387/54457/4683/4848/27154/56950/8812/144715/5458/83860/57459/23019/1616/51499/843/28984/10000/6794/2965/5985/54815/51755/2877/2033/995/94241/1874/10128/84126/5728/900/7994/905/2068/54541/1111/192669/3066/3065/2071/7157/1107/8900/5984/91875/8626/6873/5371/23112/208/10498/10542/6233/5527/2968/2475/672/55571/5932/1025/2353/604/7311/63970/7161/839/6881/5562/51616/5518/1386/55835/6880/6908/10419/5325/8851/5300/7156/581/5983/4343/6117/11198/50484/5600/7159/57472/904/6883/3276/144455/85456/79733/29883/26523/51497/5564/7874/51230/6882/5052/637/317/5565/1020/138474/133746/5884/5810/53615/10397/1022/8795/665/26155/26013/8178/5875/83695/10919/6877/7529/7296/7314/4193/5515/1263/27166/5516 273 Avian_infectious_bronchitis_virus R-HSA-5633007 Regulation of TP53 Activity 146/2292 160/10654 1.7469150184973163e-81 4.6537816092768503e-79 2.1293974646525184e-79 23368/6884/1017/23774/6875/6118/80010/5563/9891/83990/64769/7862/9156/3622/5883/1763/1029/1459/25946/7486/10111/5457/9219/6874/8445/207/22974/133383/9212/204851/6878/5982/51422/5931/1460/6749/11200/545/472/117584/53632/79813/580/8550/11073/639/7316/6872/28996/116028/890/80196/84289/1457/54971/983/6790/641/1108/8148/29117/4194/6879/5519/112858/6119/5928/3364/1432/5571/10524/10848/54457/4683/27154/56950/144715/5458/83860/57459/1616/10000/6794/5985/54815/2033/94241/84126/900/7994/1111/3066/3065/7157/1107/8900/5984/91875/8626/6873/5371/208/6233/5527/2475/672/5932/7311/7161/6881/5562/51616/5518/6880/6908/10419/8851/5300/7156/5983/6117/11198/5600/7159/6883/5564/7874/51230/6882/5565/1020/138474/133746/5884/5810/53615/26155/26013/83695/10919/6877/7314/4193/5515/1263/5516 146 Avian_infectious_bronchitis_virus R-HSA-418594 G alpha (i) signalling events 249/2292 406/10654 2.191313910061504e-70 4.864716880336539e-68 2.2259136033782647e-68 729230/2788/151/57007/10316/10803/2913/818/4544/4543/126006/10663/4889/3838/1880/26086/9283/727/351/11251/7852/5321/9294/54331/3352/8484/50833/29899/338398/5726/117579/283869/338442/59345/63940/4986/23566/6351/2358/2916/64805/2770/6752/259293/6374/1237/5539/259287/1903/2852/2550/84539/50836/1230/5594/50832/5179/3354/6753/846/4886/2841/2919/3577/2918/4987/51289/10681/5368/6754/8862/51764/259294/112/94235/114/3708/259290/301/6383/8811/2912/108/3576/56670/5196/6360/348/3827/150/113/338/5173/56923/3579/2832/5530/2357/4985/27199/2920/2826/55970/2921/1236/2853/6352/140/6751/6376/259295/165140/27198/111/107/5443/9568/4836/186/3709/3627/53637/2792/9397/54429/346562/6714/2840/2831/3361/6346/152/5957/6364/5367/80834/10563/5519/134/5540/4988/259292/1901/6370/58191/2793/5030/5136/5697/6755/1524/5733/256933/1129/643/10850/51083/2785/3355/5534/2783/624/3351/2784/4852/2782/1233/6288/6372/6366/2786/5499/50834/339403/2861/259285/2771/728/50838/2914/183/10022/5473/4283/5580/8843/1385/719/2847/6363/6373/57121/2917/2833/1268/9290/11255/50831/5518/9170/3710/6382/187/1132/2359/10874/1814/50839/83756/80835/6357/196883/6750/9672/115/259296/8698/259289/56477/5660/50835/1815/2587/1325/53829/1020/1232/9934/50840/1902/259286/3350/129521/1234/50837/2791/109/1269/59340/50865/4887/2773/2790/5515/718/2787/6387/623/5516 249 Avian_infectious_bronchitis_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 91/2292 92/10654 3.3149463512547254e-60 6.307869342673277e-58 2.886246522370656e-58 6884/1017/6875/6118/80010/5563/9891/83990/9156/5883/1763/1459/7486/10111/6874/8445/22974/9212/204851/6878/5982/51422/1460/6749/11200/545/472/53632/580/8550/11073/7316/6872/28996/116028/890/1457/6790/641/8148/4194/6879/112858/6119/3364/1432/5571/10524/54457/4683/144715/83860/6794/5985/94241/84126/1111/7157/8900/5984/6873/6233/672/5932/7311/6881/5562/51616/6880/6908/8851/5300/7156/5983/6117/11198/5600/6883/5564/6882/5565/1020/138474/5884/5810/26155/83695/6877/7314/4193/1263 91 Avian_infectious_bronchitis_virus R-HSA-449147 Signaling by Interleukins 254/2292 461/10654 1.1895624083807929e-058 1.9806214099540202e-56 9.062587295427357e-57 5295/729230/8454/3605/3557/7124/1147/5778/5718/2308/834/1052/5689/10148/3725/7291/5777/8945/596/9655/5684/5601/351/3635/6464/5290/5720/1437/3667/4790/6627/6885/6597/5606/2309/5682/90865/26469/5657/5782/5783/7412/5700/6351/3578/122706/7184/5707/27250/27178/207/246/3684/9021/7422/5690/3553/2625/1230/5594/8878/4582/5717/2919/9491/23198/6500/5908/3082/5743/3091/941/1265/25930/143471/4318/5706/3726/4312/3383/5705/301/6097/10197/6657/6778/3576/4615/7534/3313/332/3662/6776/2357/4313/7316/3565/4985/10213/5709/6175/9978/2920/5695/6352/3185/6774/4314/7335/5970/4792/3055/5443/6850/1026/6348/5780/1440/4793/3627/5714/3606/6772/8651/4609/5775/3146/9861/6364/5715/5519/5711/4988/5598/1901/3552/1432/4208/5701/867/5688/79923/3567/5687/6950/3558/4067/3717/29760/23291/4088/598/2247/836/5685/5683/5698/5708/3320/5602/5692/5686/5713/4843/2335/2534/84867/595/6195/5699/57162/5771/5710/3458/3181/10454/6288/5702/998/7157/6648/942/5719/3654/7189/6285/5609/6654/5704/6233/2885/1398/5716/7409/1385/2353/604/6196/7311/1154/6363/6347/3932/7076/5293/5518/240/302/1386/6382/9235/5296/7040/6935/3687/6197/8835/5599/5600/5784/7431/4282/375/6777/7334/6356/3600/5694/3312/1399/3574/3929/3551/7297/5781/3569/3162/57161/1278/4170/5693/1234/5721/5696/3586/5691/51231/4692/829/7314/3596/5595/5515/5516 254 Avian_infectious_bronchitis_virus R-HSA-6807070 PTEN Regulation 118/2292 140/10654 2.684469010383701e-57 3.973014135367878e-55 1.817903575452822e-55 1912/5718/5689/27161/3725/6591/5684/8841/5720/5682/5468/1822/23186/1459/5700/122706/5707/2146/5978/9112/9219/8535/10273/207/51564/6045/5690/57690/5594/84232/5717/9491/23198/27327/80012/5931/1460/143471/5706/5705/10197/192670/7316/10213/5709/5695/1457/1911/4734/5714/1108/57167/2122/11060/9861/7101/10014/5715/5711/1958/5928/5701/5688/84733/5687/57459/5685/5683/5698/5708/10000/5692/54815/5686/5713/23512/57332/5728/5699/5710/6615/5702/192669/3066/3065/7157/1107/23028/5719/5987/5371/23112/208/10542/5704/6233/2475/5716/57504/7311/1386/331/4343/8726/648/5694/23466/26523/7874/53615/5693/5721/5696/23608/5691/7314/6015/5595 118 Avian_infectious_bronchitis_virus R-HSA-9006925 Intracellular signaling by second messengers 187/2292 305/10654 1.2651688239096328e-52 1.6852048734476308e-50 7.710871042565026e-51 5295/1912/1147/5718/2308/818/5689/27161/3725/6591/3838/5684/8841/5290/5720/3667/5335/2309/5682/90865/5468/1822/23186/1459/842/5700/3815/122706/5707/2146/5978/9112/9219/8535/10273/207/51564/6045/5690/57690/5594/2069/4303/84232/5717/1027/9491/7249/23198/27327/80012/3082/930/5931/1460/112/941/143471/114/5706/3708/2064/57761/5705/10197/108/192670/4615/113/7316/10213/5709/1950/5695/111/107/1457/4233/1026/1911/4734/3709/5714/6714/2099/1108/57167/2122/11060/9861/7101/10014/5715/5519/5711/1958/5928/2932/5701/5688/84733/5159/5687/5136/57459/2247/5685/3164/5683/5698/5708/10000/5692/54815/5686/5713/2534/23512/57332/5728/5699/5710/6615/2264/3630/5702/192669/3066/3065/7157/1107/2066/23028/942/5719/5987/3654/7189/5371/23112/208/10542/5704/6233/5527/2885/5580/2475/5716/7409/1385/57504/7311/3932/5293/5518/1386/3710/1956/118788/5296/331/4343/8726/196883/648/115/5694/23466/26523/7874/5781/53615/5693/5721/5696/23608/109/5691/5156/940/7314/6015/5595/4193/5515/5516 187 Avian_infectious_bronchitis_virus R-HSA-2262752 Cellular responses to stress 251/2292 479/10654 2.2723366365007938e-52 2.7515930907445976e-50 1.259026710558813e-50 1912/5718/1017/818/3303/6118/5689/3725/9134/1019/5684/5903/5601/5720/11065/573/83667/4790/7175/5241/11258/5606/5682/9631/3159/246184/112399/7531/7290/1029/7027/1915/1783/5700/122706/7321/5707/2146/10111/8535/51807/6045/7422/8697/5690/57690/5594/93661/3308/347688/5717/1027/9491/23198/27327/80012/898/10049/5931/7295/10294/5925/55860/3091/830/7277/1051/1410/10013/143471/545/5706/472/27244/10381/5705/79813/10197/3337/192670/3576/3313/10808/10671/1780/8550/8881/29855/847/7323/1781/7316/10213/5709/9978/2114/1869/5695/890/3305/8655/6774/5970/84516/1026/1639/1911/9532/54205/832/6667/5714/4927/10121/7415/51433/9861/79902/4194/1031/7322/5715/6119/5711/5598/3552/5928/10370/1432/2932/5701/10524/5688/1387/84733/4683/5687/57805/7846/3310/2908/5685/5683/3309/5698/5708/3320/5602/5692/5686/5713/2877/2033/23512/1021/119504/7266/57332/6195/5699/5710/25842/51143/3301/7428/5702/192669/10540/9531/7157/8453/8900/51529/50507/6648/23135/7324/5719/64682/29945/10393/8091/23112/5609/8131/10542/5704/6233/51434/3326/2475/5716/3306/2353/1030/51343/6196/7311/367/9972/25906/2034/57634/10383/23411/84790/8021/9529/4343/8726/55662/6117/6197/29882/5599/6396/648/5600/5694/3304/3312/23466/26523/3456/5052/2113/405/3569/55746/5693/5721/140735/5696/7280/2288/5691/8480/10919/768/10728/829/7296/7314/51164/23523/996/6015/5595/4193/2950/1778 251 Avian_infectious_bronchitis_virus R-HSA-1257604 PIP3 activates AKT signaling 170/2292 264/10654 3.207564829886929e-52 3.5603969611744912e-50 1.6291052951794138e-50 5295/1912/1147/5718/2308/5689/27161/3725/6591/5684/8841/5290/5720/3667/2309/5682/90865/5468/1822/23186/1459/842/5700/3815/122706/5707/2146/5978/9112/9219/8535/10273/207/51564/6045/5690/57690/5594/2069/4303/84232/5717/1027/9491/7249/23198/27327/80012/3082/930/5931/1460/941/143471/5706/2064/57761/5705/10197/192670/4615/7316/10213/5709/1950/5695/1457/4233/1026/1911/4734/5714/6714/2099/1108/57167/2122/11060/9861/7101/10014/5715/5519/5711/1958/5928/2932/5701/5688/84733/5159/5687/57459/2247/5685/3164/5683/5698/5708/10000/5692/54815/5686/5713/2534/23512/57332/5728/5699/5710/6615/2264/3630/5702/192669/3066/3065/7157/1107/2066/23028/942/5719/5987/3654/7189/5371/23112/208/10542/5704/6233/5527/2885/2475/5716/7409/1385/57504/7311/3932/5293/5518/1386/1956/118788/5296/331/4343/8726/648/5694/23466/26523/7874/5781/53615/5693/5721/5696/23608/5691/5156/940/7314/6015/5595/4193/5515/5516 170 Avian_infectious_bronchitis_virus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 82/2292 86/10654 5.076613936405147e-50 4.8300355452083257e-48 2.2100447136681058e-48 8454/5718/1017/5689/8945/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/9212/5717/9491/23198/6500/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/983/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/8556/7324/5719/64682/29945/10393/9232/5704/6233/51434/5716/701/51343/7311/9184/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 82 Avian_infectious_bronchitis_virus R-HSA-453276 Regulation of mitotic cell cycle 82/2292 86/10654 5.076613936405147e-50 4.8300355452083257e-48 2.2100447136681058e-48 8454/5718/1017/5689/8945/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/9212/5717/9491/23198/6500/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/983/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/8556/7324/5719/64682/29945/10393/9232/5704/6233/51434/5716/701/51343/7311/9184/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 82 Avian_infectious_bronchitis_virus R-HSA-8953897 Cellular responses to external stimuli 251/2292 493/10654 2.5961919239820912e-49 2.305418428496097e-47 1.0548737712179867e-47 1912/5718/1017/818/3303/6118/5689/3725/9134/1019/5684/5903/5601/5720/11065/573/83667/4790/7175/5241/11258/5606/5682/9631/3159/246184/112399/7531/7290/1029/7027/1915/1783/5700/122706/7321/5707/2146/10111/8535/51807/6045/7422/8697/5690/57690/5594/93661/3308/347688/5717/1027/9491/23198/27327/80012/898/10049/5931/7295/10294/5925/55860/3091/830/7277/1051/1410/10013/143471/545/5706/472/27244/10381/5705/79813/10197/3337/192670/3576/3313/10808/10671/1780/8550/8881/29855/847/7323/1781/7316/10213/5709/9978/2114/1869/5695/890/3305/8655/6774/5970/84516/1026/1639/1911/9532/54205/832/6667/5714/4927/10121/7415/51433/9861/79902/4194/1031/7322/5715/6119/5711/5598/3552/5928/10370/1432/2932/5701/10524/5688/1387/84733/4683/5687/57805/7846/3310/2908/5685/5683/3309/5698/5708/3320/5602/5692/5686/5713/2877/2033/23512/1021/119504/7266/57332/6195/5699/5710/25842/51143/3301/7428/5702/192669/10540/9531/7157/8453/8900/51529/50507/6648/23135/7324/5719/64682/29945/10393/8091/23112/5609/8131/10542/5704/6233/51434/3326/2475/5716/3306/2353/1030/51343/6196/7311/367/9972/25906/2034/57634/10383/23411/84790/8021/9529/4343/8726/55662/6117/6197/29882/5599/6396/648/5600/5694/3304/3312/23466/26523/3456/5052/2113/405/3569/55746/5693/5721/140735/5696/7280/2288/5691/8480/10919/768/10728/829/7296/7314/51164/23523/996/6015/5595/4193/2950/1778 251 Avian_infectious_bronchitis_virus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 77/2292 80/10654 6.16328153653993e-48 5.130931879169492e-46 2.3477236905635656e-46 8454/5718/1017/5689/8945/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/6500/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/701/51343/7311/9184/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 77 Avian_infectious_bronchitis_virus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 71/2292 72/10654 1.0097708041327587e-46 7.911851241793145e-45 3.620169012958931e-45 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/9212/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/9232/5704/6233/51434/5716/51343/7311/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 71 Avian_infectious_bronchitis_virus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 73/2292 76/10654 2.7306681803617763e-45 2.0206944534677143e-43 9.245946645786365e-44 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/9232/5704/6233/51434/5716/701/7311/9184/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 73 Avian_infectious_bronchitis_virus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 72/2292 75/10654 1.2500754031199412e-44 8.588198787316976e-43 3.929640507236075e-43 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/9232/5704/6233/51434/5716/701/7311/9184/25906/29882/5694/5693/5721/5696/5691/7314/996 72 Avian_infectious_bronchitis_virus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 70/2292 72/10654 1.3539953043067306e-44 8.588198787316976e-43 3.929640507236075e-43 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/890/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/701/7311/9184/25906/29882/5694/5693/5721/5696/5691/7314/996 70 Avian_infectious_bronchitis_virus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 70/2292 72/10654 1.3539953043067306e-44 8.588198787316976e-43 3.929640507236075e-43 5718/1017/5689/9134/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/5717/9491/23198/898/143471/5706/5705/10197/8881/7316/10213/5709/5695/890/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 70 Avian_infectious_bronchitis_virus R-HSA-69620 Cell Cycle Checkpoints 171/2292 293/10654 6.060012745455946e-44 3.669062262248782e-42 1.6788264974253558e-42 5718/1017/6118/5689/5905/80010/11130/9134/5684/5903/5720/83990/11065/5682/9156/57060/246184/5883/1763/7531/51512/1029/25946/1783/1058/5700/7486/122706/7321/5707/991/10111/7532/10971/8697/5690/9212/51588/51720/5717/1027/5982/9491/23198/63967/898/7533/2810/11200/143471/545/5706/472/5705/10197/7336/6232/7534/332/580/1780/8881/11073/1781/7316/10213/5709/891/993/5695/5501/116028/890/8655/983/1026/84515/641/5714/51433/9861/79902/4194/3796/5715/9656/5519/6119/5711/3364/7341/5701/10524/5688/4683/1062/699/5687/144715/5685/5683/5698/5708/5692/5985/5686/5713/995/119504/84126/5699/5710/51143/1111/5702/7157/8900/51529/5984/7324/5719/64682/29945/10393/8924/11004/5704/6233/5527/51434/5716/701/672/7514/5932/7158/7311/9184/79184/5518/25906/5347/7156/84643/5983/6117/29882/6396/7334/5694/7465/51230/9793/10726/5884/5810/81930/55746/5693/5721/140735/5696/83695/5691/7529/7314/996/4193/5515/1778/5516 171 Avian_infectious_bronchitis_virus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 66/2292 67/10654 2.2954556031622927e-43 1.3293682014835538e-41 6.08269471043921e-42 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/9232/5704/6233/51434/5716/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 66 Avian_infectious_bronchitis_virus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 70/2292 73/10654 2.6127159587508064e-43 1.4500573571066976e-41 6.634923421564548e-42 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/890/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/701/7311/9184/25906/29882/5694/5693/5721/5696/5691/7314/996 70 Avian_infectious_bronchitis_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 79/2292 88/10654 4.6842990816495205e-43 2.4957945507028644e-41 1.1419828076947674e-41 5393/5718/3303/5689/5684/5720/5682/23404/5073/5700/122706/5707/207/5690/3184/5717/9491/3315/23198/26986/143471/5706/5705/10197/7534/7316/10213/5709/5695/5714/9861/5715/5711/1432/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/1981/5699/5710/51013/5702/5719/5704/6233/5580/5716/7514/7311/11340/8021/51010/54464/5600/5694/56915/3304/3312/8570/6418/23016/5693/54512/5721/5696/5691/118460/167227/7529/22894/7314/1994 79 Avian_infectious_bronchitis_virus R-HSA-8856688 Golgi-to-ER retrograde transport 102/2292 133/10654 2.1320230035026045e-42 1.0922517848713344e-40 4.997738133716631e-41 55582/3831/84364/22820/113220/5321/11014/9371/64837/11258/3797/1783/11127/51014/51807/9585/23095/93661/5050/347688/29127/3798/5861/55860/830/3832/7277/10381/55605/10671/1780/9554/377/1781/8398/8655/1315/23303/84516/1639/832/285643/10121/55738/3796/26153/81876/124602/10112/11316/636/1062/6836/64147/11015/7846/55614/146909/89953/56992/547/8729/23423/90990/10972/51226/51143/1314/10540/381/3834/11004/9276/3835/23046/55083/147700/10749/3833/3799/10383/24137/84790/84643/378/10945/9493/375/26286/22920/81930/26958/140735/7280/10959/54732/221458/829/51164/1778/22818/372 102 Avian_infectious_bronchitis_virus R-HSA-69615 G1/S DNA Damage Checkpoints 66/2292 68/10654 6.188170206714389e-42 3.052830635312432e-40 1.3968618127437161e-40 5718/1017/5689/9134/5684/5720/5682/57060/1029/25946/5700/122706/5707/5690/5717/1027/9491/23198/898/11200/143471/5706/472/5705/10197/7316/10213/5709/993/5695/890/1026/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/7157/8900/5719/5704/6233/5716/7311/5694/51230/5693/5721/5696/5691/7314/4193 66 Avian_infectious_bronchitis_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 91/2292 112/10654 1.0154075722471082e-41 4.8304388794041004e-40 2.21022926440254e-40 5295/8454/1147/5718/5689/5777/8945/5684/4893/5720/4790/6885/5966/5682/4690/4772/5700/122706/5707/5336/640/5690/5717/9491/23198/6500/930/143471/5706/3708/5705/10197/5530/7316/10213/5709/5695/5970/4792/6850/3709/4793/5714/9861/5715/5711/5701/5688/5687/4067/29760/23291/5685/5683/5698/5708/5692/5686/5713/2534/5534/5699/5710/5702/2280/695/5719/974/6654/30011/5704/6233/2885/5716/7409/7311/5293/3710/118788/3845/27071/5694/3265/3551/973/933/5693/5721/5696/5691/7314 91 Avian_infectious_bronchitis_virus R-HSA-69202 Cyclin E associated events during G1/S transition 75/2292 83/10654 2.1147919225539808e-41 9.713458071868628e-40 4.444517325440127e-40 8454/5718/1017/5689/9134/1019/5684/5720/902/5682/7027/5700/5707/207/5690/5717/1027/9491/6500/898/5925/5706/5705/10197/4149/91768/5934/7316/10213/5709/1869/1875/993/5695/890/4331/1026/5714/4609/9861/5715/5711/5928/5701/5688/5687/6502/5685/5683/5698/5708/10000/5692/5686/5713/1874/595/5699/5710/5702/8900/5719/208/5704/6233/5716/7311/5694/7465/1022/5693/5721/5696/5691/7314 75 Avian_infectious_bronchitis_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 76/2292 85/10654 3.670696163318704e-41 1.6297890965135046e-39 7.457309047584314e-40 8454/5718/1017/5689/9134/1019/5684/5720/902/5682/7027/5700/5707/207/5690/5717/1027/9491/6500/898/5925/5706/5705/10197/4149/91768/5934/7316/10213/5709/1869/1875/993/5695/890/4331/1026/5714/4609/9861/5715/5711/5928/5701/5688/5687/6502/5685/5683/5698/5708/10000/5692/5686/5713/1874/595/5699/5710/5702/8900/5719/208/5704/6233/5716/51343/7311/5694/7465/1022/5693/5721/5696/5691/7314 76 Avian_infectious_bronchitis_virus R-HSA-8878166 Transcriptional regulation by RUNX2 95/2292 121/10654 4.113066917749722e-41 1.7672919788524612e-39 8.086471121823734e-40 8454/57154/5718/8493/5689/7291/25/1019/5684/8841/5720/6662/5682/5700/122706/5707/23462/10273/207/5690/5594/5717/9491/23198/6500/4086/5925/10013/143471/5706/5705/10197/7316/10213/5709/9978/891/865/5695/4094/11059/9759/983/1026/10413/5714/6772/6714/2099/9861/4089/5715/5711/2932/5701/5688/5687/6502/650/4322/2908/5685/5683/5698/5708/10000/5692/5686/5713/595/55294/5699/5710/5702/861/5719/208/5704/6233/5716/7311/25937/367/860/581/5694/5693/5721/5696/4091/5691/117581/10891/7314/5595 95 Avian_infectious_bronchitis_virus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 62/2292 63/10654 1.100774885734105e-40 4.5819754618682124e-39 2.0965416409212068e-39 5718/5689/5684/5720/11065/5682/246184/5700/7321/5707/8697/5690/5717/9491/5706/5705/10197/8881/7316/10213/5709/5695/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 62 Avian_infectious_bronchitis_virus R-HSA-69563 p53-Dependent G1 DNA Damage Response 64/2292 66/10654 1.316729732599983e-40 5.158482364185816e-39 2.360329768344861e-39 5718/1017/5689/9134/5684/5720/5682/57060/1029/25946/5700/122706/5707/5690/5717/1027/9491/23198/898/11200/143471/5706/472/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/8900/5719/5704/6233/5716/7311/5694/51230/5693/5721/5696/5691/7314/4193 64 Avian_infectious_bronchitis_virus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 64/2292 66/10654 1.316729732599983e-40 5.158482364185816e-39 2.360329768344861e-39 5718/1017/5689/9134/5684/5720/5682/57060/1029/25946/5700/122706/5707/5690/5717/1027/9491/23198/898/11200/143471/5706/472/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/8900/5719/5704/6233/5716/7311/5694/51230/5693/5721/5696/5691/7314/4193 64 Avian_infectious_bronchitis_virus R-HSA-5663205 Infectious disease 197/2292 383/10654 1.9074925930905893e-39 7.259371811419042e-38 3.3216186809006054e-38 6158/6884/5718/3303/6875/5689/5905/6138/8945/6144/3837/3838/6203/5684/5903/9349/8065/4736/7852/5720/902/6194/6191/7175/6128/5606/5682/51121/6132/9631/1499/1938/3159/6147/6129/6217/5700/122706/5707/5430/6874/6230/6222/6152/5690/6136/7520/6878/6125/5717/4869/9491/23198/6500/6749/51065/6154/6141/143471/6202/5706/5705/10197/6232/6160/7316/6155/10213/5709/1500/6175/9978/6218/5695/6872/292/4233/4331/3055/4836/9397/6209/5714/6714/4927/6231/6229/11224/8148/6205/9861/79902/6130/6879/9150/5715/6142/3840/5711/6204/23327/5701/867/5688/54457/8812/5687/83860/999/5685/5683/5698/5708/9146/3320/6455/5692/2965/5686/128866/5713/2534/140801/6156/5699/905/6143/5710/2068/6181/6124/5702/2071/6207/6873/5719/5609/30011/5704/6233/2885/3326/2968/5716/7514/1025/9844/7311/6223/9972/6881/3932/51616/1213/5610/6880/6908/1211/6188/6189/8021/7040/7251/11198/6396/6135/6201/375/904/6883/5694/3304/1104/51497/2547/9045/6882/6187/138474/1022/55746/6168/5693/6208/1234/10254/5721/6137/5696/8178/5691/8480/6122/6877/7296/940/7314 197 Avian_infectious_bronchitis_virus R-HSA-453279 Mitotic G1-G1/S phases 105/2292 149/10654 6.739982419593833e-38 2.4937934952497184e-36 1.1410671991066753e-36 8454/5718/1017/6118/5689/25/894/9134/1019/5684/5720/902/5682/1029/7027/5700/5707/207/5690/5717/1027/9491/6500/7153/898/5925/5706/5705/10197/4149/91768/5934/7316/10213/5709/5422/1869/891/1875/993/5695/890/4331/983/1026/84515/5933/5714/5111/6714/4609/9861/1031/5715/5519/6119/5711/5928/5701/5688/5687/4067/3717/6502/5685/5683/5698/5708/10000/5692/5686/5713/1021/1874/595/5699/5710/5702/3065/8900/896/5719/208/5704/6233/5716/1030/7311/5518/6117/1719/5694/7465/1022/1859/5693/5721/5696/7083/5691/1028/7314/5515/6241/5516 105 Avian_infectious_bronchitis_virus R-HSA-500792 GPCR ligand binding 223/2292 468/10654 7.713771544469952e-38 2.776957756009183e-36 1.2706326384774118e-36 729230/2788/151/2532/57007/10316/10803/2913/4544/4543/2149/10663/4889/1880/9283/727/351/11251/7852/9294/54331/3352/8484/50833/5732/338398/5726/117579/283869/338442/59345/4986/23566/6351/2358/2916/64805/6863/6752/259293/1131/6374/1237/5539/259287/5734/1903/2852/2550/84539/50836/1230/50832/5179/3354/6753/846/4886/2841/2919/3577/2918/4987/51289/10681/5368/6754/8862/51764/259294/94235/259290/301/8811/2912/3576/56670/5196/6360/3827/150/1604/5173/56923/3579/2832/2357/4985/27199/2920/2826/55970/2921/1236/2853/6352/140/6751/6376/259295/165140/5020/27198/5443/6348/9568/186/6354/3627/53637/2792/54429/2840/2831/3361/6346/152/1906/6364/5367/80834/10563/134/5540/4988/259292/1901/6370/58191/2793/5030/5697/6755/1524/5733/256933/1129/643/10850/51083/2785/3355/2783/624/3351/2784/2829/4852/2782/1233/6288/6372/6366/185/2786/50834/339403/2861/259285/728/50838/2914/183/10022/5473/4283/8843/719/2847/6363/6373/57121/2917/2833/6347/1268/9290/11255/50831/9170/5731/6469/187/1132/2359/10874/1814/50839/83756/80835/6357/6356/6750/259296/8698/259289/56477/5660/50835/1815/2587/1325/53829/1232/9934/50840/1902/259286/3350/129521/1234/50837/2791/1269/59340/1813/50865/4887/2790/718/2787/6387/623 223 Avian_infectious_bronchitis_virus R-HSA-69242 S Phase 110/2292 161/10654 1.210715419977082e-37 4.243876156340719e-36 1.94183996722086e-36 8454/5718/1017/6118/5689/9134/1019/5684/5720/11065/902/5682/246184/1763/7027/5700/122706/7321/5707/207/8697/5690/5717/1027/5982/9491/23198/6500/898/5925/143471/5706/5705/10197/4149/91768/8881/5934/7316/10213/5709/5422/9978/1869/1875/993/5695/890/4331/1026/84515/5714/5111/4609/51433/9861/5715/6119/5711/5928/2932/5701/5688/5687/6502/5685/5683/5698/5708/10000/5692/5985/5686/5713/119504/1874/595/5699/5710/5702/8900/51529/5984/7324/5719/64682/29945/10393/208/5704/6233/51434/5716/51343/7311/25906/5983/6117/29882/5981/5694/10714/7465/1022/5693/5721/5696/5691/7314/996 110 Avian_infectious_bronchitis_virus R-HSA-8878159 Transcriptional regulation by RUNX3 79/2292 96/10654 4.004471369437047e-37 1.3676809907923455e-35 6.257999791913767e-36 57154/5718/5689/8463/51176/5684/5720/2309/5682/1499/2648/10018/1029/864/5700/5707/5690/5717/9491/5706/5705/6097/10197/64750/6696/7316/10213/5709/865/5695/9759/1026/10413/5714/6714/4609/9861/4089/5715/22938/8850/5711/5701/5688/1387/5687/4088/5685/5683/5698/5708/5692/5686/5713/2033/595/5699/5710/5702/7157/861/5719/9794/5704/6233/5716/7311/25937/7040/3845/5694/3516/4851/5693/5721/5696/5691/7314/4193 79 Avian_infectious_bronchitis_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 97/2292 134/10654 1.0909240856549244e-36 3.632777205230898e-35 1.6622238041952664e-35 5295/8454/1147/5718/5689/3725/8945/5684/5601/4893/6464/5290/5720/5335/4790/6885/5682/4772/5700/122706/7321/5707/5336/5690/5594/5717/4214/9491/23198/6500/143471/5706/3708/5705/10197/5530/7316/10213/5709/5695/7335/5970/4792/6850/3709/5714/9861/7322/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5602/5692/5686/5713/2534/5534/5699/5710/10454/5702/695/5719/7189/5609/6654/5704/6233/2885/7410/5716/7409/2353/7311/3710/5296/3845/5599/7334/5694/3265/3551/5693/5721/5696/997/5691/7314/5595 97 Avian_infectious_bronchitis_virus R-HSA-69052 Switching of origins to a post-replicative state 75/2292 90/10654 4.84576882965223e-36 1.5742839222187242e-34 7.203338003513842e-35 8454/5718/1017/5689/9134/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/5717/9491/23198/6500/898/143471/5706/5705/10197/8881/7316/10213/5709/9978/5695/890/84515/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 75 Avian_infectious_bronchitis_virus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 55/2292 56/10654 5.283320192045867e-36 1.675567260905975e-34 7.666772910262047e-35 5718/3303/5689/5684/5720/5682/5700/122706/5707/5690/3184/5717/9491/3315/23198/26986/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/1981/5699/5710/5702/5719/5704/6233/5716/7311/5694/3304/3312/5693/5721/5696/5691/7314 55 Avian_infectious_bronchitis_virus R-HSA-9006936 Signaling by TGF-beta family members 81/2292 102/10654 7.241837578436169e-36 2.2432855010411577e-34 1.026444053345053e-34 4093/57154/5590/892/7027/9765/7321/51377/6497/10273/4738/9372/4086/658/51592/3726/64750/659/130399/7323/8239/54778/7316/1875/9611/5501/91/93/3624/9612/56937/1024/6667/5933/4092/4609/4089/22938/11171/60436/23327/867/8812/7050/7046/92/4088/650/1874/142/905/5494/3065/2280/6498/9958/9040/4087/5499/657/6233/3625/7514/7048/1025/1030/7311/56288/25937/9110/8928/387/7040/10589/904/23439/4091/4090/7314/4221/5054 81 Avian_infectious_bronchitis_virus R-HSA-8941858 Regulation of RUNX3 expression and activity 54/2292 55/10654 2.457677448073783e-35 7.4400599109869976e-34 3.404294838360575e-34 57154/5718/5689/5684/5720/5682/1029/864/5700/5707/5690/5717/9491/5706/5705/10197/64750/7316/10213/5709/865/5695/5714/6714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/2033/5699/5710/5702/5719/5704/6233/5716/7311/7040/5694/5693/5721/5696/5691/7314/4193 54 Avian_infectious_bronchitis_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 80/2292 101/10654 2.746157798447629e-35 7.9607733064121e-34 3.6425539310989462e-34 8454/1147/5718/5689/8945/5684/5720/4790/6885/5682/4772/5700/122706/7321/5707/5336/5690/3553/9039/5717/9491/23198/6500/143471/5706/3708/5705/841/10197/5530/7316/10213/5709/5695/7335/5970/4792/6850/3709/5714/6714/9861/7322/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5534/5699/5710/10454/5702/9040/5719/7189/5704/6233/5580/5716/7311/5971/3710/7334/5694/3551/5693/5721/5696/997/5691/7314 80 Avian_infectious_bronchitis_virus R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic 79/2292 99/10654 2.749216006718893e-35 7.9607733064121e-34 3.6425539310989462e-34 55582/3831/84364/22820/113220/11014/9371/64837/3797/11127/51014/51807/9585/23095/347688/29127/3798/5861/3832/7277/10381/55605/9554/377/1315/23303/285643/55738/3796/26153/81876/124602/10112/11316/1062/6836/64147/11015/7846/55614/146909/89953/56992/547/8729/23423/90990/10972/51226/1314/381/3834/11004/9276/3835/23046/55083/147700/10749/3833/3799/10383/24137/84790/84643/378/10945/9493/375/26286/22920/81930/26958/7280/10959/54732/221458/22818/372 79 Avian_infectious_bronchitis_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 65/2292 73/10654 4.312319663175461e-35 1.2221297428403646e-33 5.592011388529882e-34 8454/57154/5718/5689/7291/5684/5720/5682/5700/122706/5707/10273/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/865/5695/11059/5714/6772/2099/9861/5715/5711/2932/5701/5688/5687/6502/650/2908/5685/5683/5698/5708/5692/5686/5713/55294/5699/5710/5702/5719/5704/6233/5716/7311/860/5694/5693/5721/5696/5691/10891/7314 65 Avian_infectious_bronchitis_virus R-HSA-446652 Interleukin-1 family signaling 98/2292 140/10654 4.836718736403821e-35 1.3421894493520604e-33 6.141359974512747e-34 8454/3557/1147/5778/5718/834/5689/5777/8945/5684/351/5720/4790/6885/5682/90865/26469/5782/5783/5700/122706/5707/27178/5690/3553/8878/5717/9491/23198/6500/25930/143471/5706/5705/10197/4615/7316/3565/10213/5709/9978/5695/6774/7335/5970/4792/5780/4793/5714/3606/5775/3146/9861/5715/5711/3552/5701/5688/5687/23291/4088/5685/5683/5698/5708/5692/5686/5713/84867/5699/57162/5771/5710/10454/6288/5702/5719/3654/7189/6285/5704/6233/5716/7311/240/5599/5784/7334/5694/3551/5781/57161/5693/5721/5696/5691/7314/3596 98 Avian_infectious_bronchitis_virus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 57/2292 60/10654 9.034412750867565e-35 2.4067675568311194e-33 1.1012473647899621e-33 8454/5718/1017/5689/9134/1019/5684/5720/5682/5700/5707/5690/5717/1027/9491/6500/898/5706/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/595/5699/5710/5702/8900/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 57 Avian_infectious_bronchitis_virus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 57/2292 60/10654 9.034412750867565e-35 2.4067675568311194e-33 1.1012473647899621e-33 8454/1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/9039/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5970/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5971/5694/5693/5721/5696/5691/7314 57 Avian_infectious_bronchitis_virus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 53/2292 54/10654 1.1424774275647672e-34 2.9838822225809215e-33 1.3653135821671832e-33 8454/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/6790/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/23194/5694/5693/5721/5696/5691/7314 53 Avian_infectious_bronchitis_virus R-HSA-69541 Stabilization of p53 55/2292 57/10654 1.1936192177221346e-34 3.0575015346266987e-33 1.398999042633838e-33 5718/5689/5684/5720/5682/1029/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/472/5705/10197/7316/10213/5709/5695/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/51230/5693/5721/5696/5691/7314/4193 55 Avian_infectious_bronchitis_virus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 56/2292 59/10654 4.0678153677725e-34 1.0223264282779188e-32 4.677785696008496e-33 8454/1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/9039/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5971/5694/5693/5721/5696/5691/7314 56 Avian_infectious_bronchitis_virus R-HSA-109581 Apoptosis 113/2292 178/10654 4.73719755546022e-34 1.1685087303468544e-32 5.346661568443407e-33 23368/4000/5718/5689/2934/27113/3837/596/5684/5720/1612/5682/1499/4976/10018/7531/5747/1029/7027/842/5700/122706/5707/7532/207/10971/5690/5594/5717/9491/23198/63967/355/7533/2810/143471/5706/1829/5705/841/10197/7099/7534/7316/10213/5709/1869/5695/8655/7082/6774/54205/5339/4836/5366/5714/8797/3146/9861/5715/5711/5701/28988/5688/5687/999/598/836/5685/5683/5698/5708/10000/5692/5686/5713/8837/5534/5699/5710/5702/7157/8626/5719/208/5704/6233/5580/6709/5716/1613/7311/7161/839/331/581/5599/7159/7431/5694/26060/637/317/8795/5693/5721/140735/5696/5691/7529/7314/578/5595 113 Avian_infectious_bronchitis_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 64/2292 73/10654 1.1733465711825699e-33 2.8416320596639696e-32 1.3002251956262353e-32 57154/5590/892/7027/7321/51377/6497/10273/4738/9372/51592/3726/64750/7323/8239/54778/7316/1875/9611/5501/9612/56937/1024/6667/5933/4092/4609/4089/22938/11171/60436/23327/867/8812/7050/7046/4088/1874/142/905/5494/3065/2280/6498/9958/9040/4087/5499/6233/7514/7048/1025/1030/7311/56288/25937/9110/387/7040/904/23439/7314/4221/5054 64 Avian_infectious_bronchitis_virus R-HSA-69239 Synthesis of DNA 87/2292 119/10654 1.4725778345460074e-33 3.5026315635987176e-32 1.6026739966205608e-32 8454/5718/1017/6118/5689/9134/5684/5720/11065/5682/246184/1763/5700/122706/7321/5707/8697/5690/5717/5982/9491/23198/6500/898/143471/5706/5705/10197/8881/7316/10213/5709/5422/9978/5695/890/84515/5714/5111/51433/9861/5715/6119/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5985/5686/5713/119504/5699/5710/5702/8900/51529/5984/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/5983/6117/29882/5981/5694/10714/5693/5721/5696/5691/7314/996 87 Avian_infectious_bronchitis_virus R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 51/2292 52/10654 2.4636917397205e-33 5.438334150079705e-32 2.488379542355105e-32 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Avian_infectious_bronchitis_virus R-HSA-69610 p53-Independent DNA Damage Response 51/2292 52/10654 2.4636917397205e-33 5.438334150079705e-32 2.488379542355105e-32 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Avian_infectious_bronchitis_virus R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 51/2292 52/10654 2.4636917397205e-33 5.438334150079705e-32 2.488379542355105e-32 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Avian_infectious_bronchitis_virus R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 51/2292 52/10654 2.4636917397205e-33 5.438334150079705e-32 2.488379542355105e-32 5718/5689/1019/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/595/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Avian_infectious_bronchitis_virus R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 53/2292 55/10654 2.4905284020635287e-33 5.438334150079705e-32 2.488379542355105e-32 8454/5718/5689/8945/5684/5720/5682/5700/122706/5707/991/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/51343/7311/5694/5693/5721/5696/5691/7314 53 Avian_infectious_bronchitis_virus R-HSA-69206 G1/S Transition 92/2292 131/10654 3.855701303085189e-33 8.283538928563664e-32 3.7902394813010604e-32 8454/5718/1017/6118/5689/9134/1019/5684/5720/902/5682/7027/5700/5707/207/5690/5717/1027/9491/6500/898/5925/5706/5705/10197/4149/91768/5934/7316/10213/5709/5422/1869/891/1875/993/5695/890/4331/983/1026/84515/5933/5714/5111/4609/9861/5715/5519/6119/5711/5928/5701/5688/5687/6502/5685/5683/5698/5708/10000/5692/5686/5713/1874/595/5699/5710/5702/3065/8900/5719/208/5704/6233/5716/7311/5518/6117/1719/5694/7465/1022/5693/5721/5696/7083/5691/7314/5515/6241/5516 92 Avian_infectious_bronchitis_virus R-HSA-5357801 Programmed Cell Death 113/2292 181/10654 4.6013840075187864e-33 9.72864047303972e-32 4.4514642278251926e-32 23368/4000/5718/5689/2934/27113/3837/596/5684/5720/1612/5682/1499/4976/10018/7531/5747/1029/7027/842/5700/122706/5707/7532/207/10971/5690/5594/5717/9491/23198/63967/355/7533/2810/143471/5706/1829/5705/841/10197/7099/7534/7316/10213/5709/1869/5695/8655/7082/6774/54205/5339/4836/5366/5714/8797/3146/9861/5715/5711/5701/28988/5688/5687/999/598/836/5685/5683/5698/5708/10000/5692/5686/5713/8837/5534/5699/5710/5702/7157/8626/5719/208/5704/6233/5580/6709/5716/1613/7311/7161/839/331/581/5599/7159/7431/5694/26060/637/317/8795/5693/5721/140735/5696/5691/7529/7314/578/5595 113 Avian_infectious_bronchitis_virus R-HSA-5687128 MAPK6/MAPK4 signaling 72/2292 89/10654 5.4567267795833226e-33 1.135681261000779e-31 5.196455272004513e-32 5718/2308/5689/27161/3725/5684/5720/2309/5682/5700/10642/122706/5707/5690/57690/5717/9491/3315/23198/27327/143471/5706/5705/10197/3337/192670/8550/7316/10213/5709/5695/983/5597/5714/4609/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/8555/5702/192669/998/8556/896/5719/23112/5704/6233/5716/7514/7311/4343/5694/26523/8202/5693/5721/5696/5691/7314 72 Avian_infectious_bronchitis_virus R-HSA-5663202 Diseases of signal transduction 184/2292 377/10654 6.012597836435707e-33 1.2321200489434402e-31 5.637723315459554e-32 5295/8454/4000/1147/5718/2308/818/27123/5689/8805/5684/4893/6464/8841/5290/5720/3667/5335/1487/142678/2309/5682/1499/2648/10018/9734/892/842/5700/3815/122706/5707/5430/8844/23462/207/51564/7094/1452/5690/5594/2069/4303/613/5717/1027/9372/9491/7249/23198/6500/409/5908/3082/930/7414/941/10533/10013/143471/5706/2064/5705/10197/6776/84447/7316/10213/5709/9978/1950/9611/5695/8315/6774/4233/9759/9612/1026/1024/5714/6772/6714/2099/4609/7415/9861/4089/10014/5715/22938/5519/8850/5711/2932/5701/867/5688/1387/5159/5687/7046/3717/4088/2247/5685/3164/5683/5698/5708/10000/3320/5692/5686/26508/5713/2335/2534/2033/54894/408/55294/5728/5699/8312/1445/5710/2264/5702/3066/3065/2280/2066/5894/4087/942/5719/208/9794/6654/5704/6233/5527/2885/2475/5716/7409/56829/1385/7048/7311/8826/3932/5293/5518/6469/1956/60/118788/5296/7040/3845/6777/5694/3265/3516/369/4763/5781/4851/5693/5663/5721/5696/5691/5245/7529/5156/940/7314/5595/4193/5515/5516 184 Avian_infectious_bronchitis_virus R-HSA-4641258 Degradation of DVL 54/2292 57/10654 8.215986173333117e-33 1.658135391345411e-31 7.587011155278908e-32 5718/5689/5684/5720/5682/5700/122706/5707/1856/5690/5717/9491/23198/143471/5706/5705/10197/8452/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/1855/5716/1857/23072/7311/5694/5693/5721/5696/5691/7314 54 Avian_infectious_bronchitis_virus R-HSA-1169091 Activation of NF-kappaB in B cells 60/2292 67/10654 8.499521153453178e-33 1.6897555487163632e-31 7.731693240925987e-32 8454/1147/5718/5689/8945/5684/5720/4790/6885/5966/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5970/4792/4793/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/3551/5693/5721/5696/5691/7314 60 Avian_infectious_bronchitis_virus R-HSA-9604323 Negative regulation of NOTCH4 signaling 52/2292 54/10654 1.1359147291263072e-32 2.2250564988180018e-31 1.0181031395729597e-31 8454/5718/5689/5684/5720/5682/5700/5707/207/5690/5717/9491/6500/5706/5705/10197/7534/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/4855/55294/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 52 Avian_infectious_bronchitis_virus R-HSA-8948751 Regulation of PTEN stability and activity 61/2292 69/10654 1.365107237588614e-32 2.635250493431933e-31 1.205792662950126e-31 5718/5689/5684/5720/5682/1459/5700/122706/5707/10273/207/5690/5717/9491/23198/1460/143471/5706/5705/10197/7316/10213/5709/5695/1457/4734/5714/11060/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/10000/5692/5686/5713/5728/5699/5710/5702/5719/5987/208/5704/6233/5716/7311/331/5694/5693/5721/5696/23608/5691/7314 61 Avian_infectious_bronchitis_virus R-HSA-373076 Class A/1 (Rhodopsin-like receptors) 169/2292 335/10654 1.5766894971748948e-32 3.0002148717670854e-31 1.3727867952846078e-31 729230/151/2532/57007/10316/10803/4544/4543/2149/10663/4889/1880/9283/727/351/11251/7852/9294/3352/8484/5732/117579/283869/338442/4986/23566/6351/2358/64805/6863/6752/1131/6374/1237/5539/5734/1903/2852/84539/1230/5179/3354/6753/4886/2841/2919/3577/4987/51289/5368/6754/8862/301/8811/3576/56670/5196/6360/3827/150/5173/56923/3579/2832/2357/4985/27199/2920/2826/2921/1236/2853/6352/140/6751/6376/165140/5020/27198/5443/6348/186/6354/3627/53637/2840/2831/3361/6346/152/1906/6364/5367/10563/134/5540/4988/1901/6370/58191/5030/5697/6755/1524/5733/256933/1129/643/10850/51083/3355/624/3351/2829/4852/1233/6288/6372/6366/185/339403/2861/728/183/10022/5473/4283/8843/719/2847/6363/6373/57121/2833/6347/1268/9290/11255/9170/5731/187/1132/2359/10874/1814/6357/6356/6750/8698/56477/5660/1815/2587/1325/53829/1232/9934/1902/3350/129521/1234/1269/59340/1813/50865/4887/718/6387/623 169 Avian_infectious_bronchitis_virus R-HSA-69481 G2/M Checkpoints 107/2292 168/10654 1.76828213461784e-32 3.317396906071779e-31 1.5179175032523788e-31 5718/1017/6118/5689/80010/5684/5720/83990/5682/9156/5883/1763/7531/51512/5700/7486/122706/5707/10111/7532/10971/5690/51588/51720/5717/5982/9491/23198/63967/7533/2810/11200/143471/545/5706/472/5705/10197/7336/7534/580/11073/7316/10213/5709/891/993/5695/116028/983/84515/641/5714/9861/5715/9656/6119/5711/3364/7341/5701/10524/5688/4683/5687/144715/5685/5683/5698/5708/5692/5985/5686/5713/995/84126/5699/5710/1111/5702/7157/5984/5719/8924/5704/6233/5716/672/5932/7158/7311/79184/7156/5983/6117/7334/5694/7465/5884/5810/5693/5721/5696/83695/5691/7529/7314 107 Avian_infectious_bronchitis_virus R-HSA-1234174 Cellular response to hypoxia 64/2292 75/10654 3.72088753287256e-32 6.8836419358142365e-31 3.1496986572122985e-31 5718/5689/5684/5720/5682/112399/5700/122706/7321/5707/7422/5690/5717/9491/23198/3091/143471/5706/5705/10197/7323/7316/10213/5709/9978/5695/5714/9861/7322/5715/5711/10370/5701/5688/1387/5687/5685/5683/5698/5708/5692/5686/5713/2033/5699/5710/7428/5702/8453/5719/5704/6233/5716/7311/2034/55662/5694/405/5693/5721/5696/5691/768/7314 64 Avian_infectious_bronchitis_virus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 107/2292 171/10654 1.7387812918388824e-31 3.17268038456081e-30 1.4517006027032632e-30 6158/5718/5689/6138/6144/6203/5684/9349/4736/5720/6194/6191/6128/5682/51121/6132/6147/6129/6217/5700/122706/5707/6230/6222/6152/5690/6136/6125/5717/9491/23198/51065/6154/6141/26986/143471/6202/5706/5705/3670/10197/6232/2935/6160/7316/6155/10213/5709/6175/9978/6218/5695/6209/5714/6231/6229/11224/6205/9861/6130/5715/6142/5711/6204/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/1981/140801/6156/5699/6143/5710/6181/6124/5702/8453/6207/5719/5704/6233/5716/7311/6223/6188/6189/6135/6201/5694/9045/6187/6168/5693/6208/5721/6137/5696/5691/6122/7314 107 Avian_infectious_bronchitis_virus R-HSA-5610780 Degradation of GLI1 by the proteasome 55/2292 60/10654 2.034617106308621e-31 3.662310791355518e-30 1.675737275323886e-30 8454/5718/5689/8945/5684/5720/2735/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/8650/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/83737/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 55 Avian_infectious_bronchitis_virus R-HSA-180534 Vpu mediated degradation of CD4 50/2292 52/10654 2.355499338646207e-31 4.1283225251009836e-30 1.888966921158108e-30 5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Avian_infectious_bronchitis_virus R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/2292 52/10654 2.355499338646207e-31 4.1283225251009836e-30 1.888966921158108e-30 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/472/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Avian_infectious_bronchitis_virus R-HSA-69306 DNA Replication 88/2292 127/10654 4.823607395520531e-31 8.34421435173162e-30 3.818002299393558e-30 8454/5718/1017/6118/5689/9134/5684/5720/11065/5682/246184/1763/5700/122706/7321/5707/8697/5690/5717/5982/9491/23198/6500/898/143471/5706/5705/10197/8881/7316/10213/5709/5422/9978/1869/5695/890/84515/5714/5111/51433/9861/5715/6119/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5985/5686/5713/119504/5699/5710/5702/8900/51529/5984/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/5983/6117/29882/5981/5694/10714/5693/5721/5696/5691/7314/996 88 Avian_infectious_bronchitis_virus R-HSA-453274 Mitotic G2-G2/M phases 117/2292 198/10654 5.605124460684307e-31 9.571827925168586e-30 4.379712635271544e-30 10844/8454/115106/5718/1017/5689/8945/22995/5684/5720/902/2305/11258/5682/22981/7531/51512/4659/5700/122706/5707/203068/54801/51807/7532/1454/22974/5690/347688/5717/9491/23198/6500/51400/7277/143471/5706/10381/5705/10197/1781/7316/10213/728642/5709/9978/1869/891/993/5695/890/8655/4331/983/1026/1639/6790/5714/10121/9861/5715/5519/5711/5928/5701/5688/5687/23291/7846/5685/7283/5683/5698/5708/3320/5692/5686/5713/80097/2033/995/5699/5710/5702/10540/7157/8900/5719/5704/6233/3326/5716/7514/7311/54930/23194/5518/10383/55835/5347/84790/9662/5694/1453/7465/9793/1022/8481/5693/5721/5696/7280/5691/7314/5515/1778/5516 117 Avian_infectious_bronchitis_virus R-HSA-69275 G2/M Transition 116/2292 196/10654 8.257434156930529e-31 1.3922661135482866e-29 6.370492174367457e-30 10844/8454/115106/5718/1017/5689/8945/22995/5684/5720/902/2305/11258/5682/22981/7531/51512/4659/5700/122706/5707/203068/54801/51807/7532/1454/22974/5690/347688/5717/9491/23198/6500/51400/7277/143471/5706/10381/5705/10197/1781/7316/10213/728642/5709/9978/891/993/5695/890/8655/4331/983/1026/1639/6790/5714/10121/9861/5715/5519/5711/5928/5701/5688/5687/23291/7846/5685/7283/5683/5698/5708/3320/5692/5686/5713/80097/2033/995/5699/5710/5702/10540/7157/8900/5719/5704/6233/3326/5716/7514/7311/54930/23194/5518/10383/55835/5347/84790/9662/5694/1453/7465/9793/1022/8481/5693/5721/5696/7280/5691/7314/5515/1778/5516 116 Avian_infectious_bronchitis_virus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 64/2292 77/10654 8.772726829798182e-31 1.4606590171613972e-29 6.683432676912036e-30 5718/5689/5684/5720/5682/51512/5700/122706/5707/51807/5690/347688/5717/9491/23198/7277/143471/5706/10381/5705/10197/7316/10213/5709/891/5695/983/1026/5714/9861/5715/5711/5701/5688/5687/7846/5685/5683/5698/5708/3320/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/3326/5716/7311/10383/5347/84790/5694/5693/5721/5696/7280/5691/7314 64 Avian_infectious_bronchitis_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 67/2292 83/10654 1.1457547142116453e-30 1.8841299744813722e-29 8.6210783564463e-30 8454/1147/5718/5689/8945/5684/4893/5720/4790/6885/5966/5682/4772/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/5530/7316/10213/5709/5695/5970/4792/4793/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5534/5699/5710/5702/2280/5719/5704/6233/5716/7311/3845/5694/3265/3551/5693/5721/5696/5691/7314 67 Avian_infectious_bronchitis_virus R-HSA-375276 Peptide ligand-binding receptors 117/2292 201/10654 3.927976757988539e-30 6.380567123952114e-29 2.9195103246153585e-29 729230/2532/57007/10316/10803/2149/10663/4889/9283/727/351/7852/8484/117579/283869/4986/6351/2358/6863/6752/6374/1237/5539/2852/84539/1230/5179/6753/4886/2919/3577/4987/51289/5368/6754/8862/301/8811/3576/5196/6360/3827/5173/56923/3579/2832/2357/4985/2920/2826/2921/1236/6352/6751/6376/5020/5443/6348/186/6354/3627/2831/6346/1906/6364/5367/10563/5540/4988/6370/58191/5697/6755/1524/256933/643/10850/51083/624/2829/4852/1233/6288/6372/6366/185/339403/2861/728/183/10022/5473/4283/719/2847/6363/6373/2833/6347/187/2359/10874/6357/6356/6750/56477/5660/2587/1325/1232/129521/1234/50865/4887/718/6387/623 117 Avian_infectious_bronchitis_virus R-HSA-2871837 FCERI mediated NF-kB activation 66/2292 82/10654 4.3970598682507865e-30 7.056486439168732e-29 3.228785876622962e-29 8454/1147/5718/5689/8945/5684/5720/4790/6885/5682/5700/122706/7321/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/7335/5970/4792/5714/9861/7322/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/10454/5702/5719/7189/5704/6233/5716/7311/7334/5694/3551/5693/5721/5696/997/5691/7314 66 Avian_infectious_bronchitis_virus R-HSA-3858494 Beta-catenin independent WNT signaling 95/2292 146/10654 4.79960805156171e-30 7.610807053190711e-29 3.4824223832759775e-29 2788/57154/5718/5689/27161/51176/5684/5720/54331/6885/5682/1499/59345/51701/4772/5700/122706/5707/1856/5690/1212/57690/5717/9491/23198/10681/27327/409/51764/94235/143471/5706/3708/5705/10197/192670/64750/5530/7316/10213/5709/5695/55970/3709/2792/5714/9861/5715/5711/5701/5688/2793/5687/5685/5683/5698/5708/5692/5686/5713/2785/5534/5699/2783/2784/5710/2782/5702/192669/2786/5719/23112/5704/6233/1855/5716/1857/7311/1213/387/3710/1211/4343/3845/5694/26523/5693/5721/2791/5696/6259/5691/7314/2790/2787 95 Avian_infectious_bronchitis_virus R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 48/2292 50/10654 4.863091929924563e-30 7.620751118422962e-29 3.4869724178654146e-29 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 48 Avian_infectious_bronchitis_virus R-HSA-9020702 Interleukin-1 signaling 76/2292 103/10654 6.622443466149122e-30 1.0257086856872827e-28 4.69326164859283e-29 8454/3557/1147/5718/5689/8945/5684/351/5720/4790/6885/5682/5700/122706/5707/5690/3553/8878/5717/9491/23198/6500/143471/5706/5705/10197/4615/7316/10213/5709/9978/5695/7335/5970/4792/4793/5714/3146/9861/5715/5711/3552/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/57162/5710/10454/6288/5702/5719/3654/7189/6285/5704/6233/5716/7311/7334/5694/3551/57161/5693/5721/5696/5691/7314 76 Avian_infectious_bronchitis_virus R-HSA-5610783 Degradation of GLI2 by the proteasome 54/2292 60/10654 7.002308330651178e-30 1.0598948518667466e-28 4.84968483665913e-29 8454/5718/5689/8945/5684/5720/5682/5700/122706/5707/1452/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 54 Avian_infectious_bronchitis_virus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 54/2292 60/10654 7.002308330651178e-30 1.0598948518667466e-28 4.84968483665913e-29 8454/5718/5689/8945/5684/5720/5682/5700/122706/5707/1452/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 54 Avian_infectious_bronchitis_virus R-HSA-5621481 C-type lectin receptors (CLRs) 93/2292 142/10654 9.134301369057231e-30 1.3670662273690148e-28 6.25518686302086e-29 8454/1147/5718/5689/8945/4586/5684/4893/5720/4790/6885/5682/4772/5700/122706/7321/5707/5336/5690/3553/9039/4582/5717/9491/23198/6500/3384/143471/5706/3708/5705/841/10197/5530/7316/10213/5709/5695/7335/5970/4792/6850/3709/5714/6714/9861/7322/5715/5711/5701/5688/1387/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/2534/2033/5534/5699/3385/5710/10454/5702/9040/5894/5719/7189/5704/6233/5580/30835/5716/7311/5971/3710/3845/7334/5694/3265/3551/5693/5721/5696/997/5691/7314 93 Avian_infectious_bronchitis_virus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 47/2292 49/10654 2.205866778081349e-29 3.2646828315603964e-28 1.4937975023498258e-28 1017/9134/1820/57060/7027/25946/7832/4849/1027/4869/898/4850/2810/9337/5934/1869/891/890/10769/983/1026/6790/5933/5111/25904/246175/1647/4848/23019/28984/2033/995/1874/7157/8900/10498/55571/55835/5325/581/57472/3276/144455/85456/79733/29883/1263 47 Avian_infectious_bronchitis_virus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 57/2292 66/10654 2.4248415283020783e-29 3.5493284787894156e-28 1.6240407690999464e-28 5718/5689/5684/5720/5682/112399/5700/122706/7321/5707/5690/5717/9491/23198/3091/143471/5706/5705/10197/7323/7316/10213/5709/9978/5695/5714/9861/7322/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/7428/5702/8453/5719/5704/6233/5716/7311/2034/5694/5693/5721/5696/5691/7314 57 Avian_infectious_bronchitis_virus R-HSA-8878171 Transcriptional regulation by RUNX1 130/2292 239/10654 2.459046918850842e-29 3.560272278162306e-28 1.6290482448680065e-28 55904/1912/5718/9070/5689/27161/25/894/5684/5720/902/1437/11091/6597/5682/6929/1459/5700/122706/5707/640/8535/6045/9021/5690/2625/57690/5717/5929/9491/23198/27327/80012/1460/143471/6938/5706/6598/5705/10197/6599/192670/200845/5196/86/7316/10213/5709/865/5695/28996/5079/10398/7082/1457/4331/1911/6603/10413/5714/23309/6714/2099/9861/5715/8850/5711/5701/5688/1387/84733/5687/3558/5685/5683/8289/5698/5708/5692/5686/5713/2033/1021/6602/57332/595/50943/5699/4602/8312/5710/3458/5702/192669/3065/83737/861/896/5719/5371/23112/5704/6233/9757/5716/7311/7161/860/58508/25942/9739/4343/648/3276/5694/6601/23466/26523/5781/7057/1022/1493/5693/5721/23429/4297/5696/5691/7314/6015 130 Avian_infectious_bronchitis_virus R-HSA-180585 Vif-mediated degradation of APOBEC3G 50/2292 54/10654 3.530302918618461e-29 5.056304825376118e-28 2.313577124935019e-28 5718/5689/5684/8065/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Avian_infectious_bronchitis_virus R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 51/2292 56/10654 7.146404133634842e-29 1.012660670851235e-27 4.6335587831742145e-28 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/84447/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 51 Avian_infectious_bronchitis_virus R-HSA-6807878 COPI-mediated anterograde transport 74/2292 101/10654 8.159384835541735e-29 1.1440316422043779e-27 5.234663512220128e-28 2348/84364/6811/22820/6711/11014/11258/6712/1783/51014/51807/286/2801/93661/347688/5861/55860/830/7277/10381/10671/1780/1604/377/1781/9570/966/8655/1315/84516/1639/832/57731/10282/10121/55738/8615/6710/81876/11316/11015/7846/8729/23423/10972/51226/51143/1314/3630/10540/381/6708/9276/287/6709/51332/10383/84790/378/10945/375/26286/288/26958/140735/7280/10959/10652/54732/829/51164/1778/22818/372 74 Avian_infectious_bronchitis_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 77/2292 108/10654 1.2635838100227808e-28 1.7532225364066084e-27 8.022094583368313e-28 5295/3605/7124/2308/1052/7291/596/9655/2309/7412/7184/207/246/3684/9021/7422/3553/2625/4582/3082/5743/3091/4318/3726/4312/3383/301/6097/6657/6778/3576/332/3662/4313/3565/4985/6774/4314/5443/1026/3606/6772/8651/4609/4988/1901/3552/79923/3717/598/2247/3320/4843/2335/595/6288/7157/2353/604/6347/7076/240/7040/6935/3687/7431/6356/3312/3929/7297/3569/3162/1278/4170/3586/4692/3596 77 Avian_infectious_bronchitis_virus R-HSA-169911 Regulation of Apoptosis 49/2292 53/10654 1.5455905418742002e-28 2.122398558532407e-27 9.711306823061985e-28 5718/5689/5684/5720/5682/4976/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 49 Avian_infectious_bronchitis_virus R-HSA-4641257 Degradation of AXIN 50/2292 55/10654 3.0784129824655227e-28 4.184128665963343e-27 1.9145017366783437e-27 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/64750/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/8312/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Avian_infectious_bronchitis_virus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 43/2292 44/10654 5.170395822592956e-28 6.956532561306887e-27 3.1830506978004486e-27 892/7027/7321/6497/51592/3726/64750/7323/8239/54778/7316/1875/9611/9612/1024/6667/5933/4092/4609/4089/22938/60436/23327/8812/7050/4088/1874/142/905/5494/3065/6498/4087/6233/1025/1030/7311/25937/904/23439/7314/4221/5054 43 Avian_infectious_bronchitis_virus R-HSA-5658442 Regulation of RAS by GAPs 57/2292 68/10654 6.310989647207651e-28 8.406238210080592e-27 3.846382111298137e-27 5718/5689/5684/4893/5720/5682/153090/5700/122706/5707/5690/5717/9491/23198/143471/5706/5921/5705/10197/8452/7316/10213/5709/9978/5695/84078/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/3845/5694/3265/4763/5693/5721/5696/5691/7314 57 Avian_infectious_bronchitis_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 64/2292 82/10654 8.747983842422611e-28 1.1423837723634233e-26 5.227123472407319e-27 8454/5718/5689/51176/8945/5684/5720/1487/5682/1499/5700/122706/5707/1452/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5519/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/8312/5710/5702/3065/5719/5704/6233/5527/5716/7311/5518/5694/5693/5721/5696/5691/7314/5515/5516 64 Avian_infectious_bronchitis_virus R-HSA-9013694 Signaling by NOTCH4 64/2292 82/10654 8.747983842422611e-28 1.1423837723634233e-26 5.227123472407319e-27 8454/5718/5689/5684/5720/5682/2648/5700/5707/23462/207/5690/5717/9491/6500/5706/5705/10197/7534/7316/10213/5709/9978/5695/5714/9861/5715/22938/8850/5711/5701/5688/1387/5687/4088/5685/5683/5698/5708/59/5692/5686/5713/2033/4855/55294/5699/5710/5702/5719/9794/5704/6233/5716/7311/5694/3516/4851/5693/5663/5721/5696/5691/7314 64 Avian_infectious_bronchitis_virus R-HSA-2467813 Separation of Sister Chromatids 109/2292 190/10654 2.155653406723065e-27 2.7876993570438086e-26 1.2755475958024066e-26 5718/5689/5905/11130/5684/5903/5720/11065/5682/246184/1783/1058/5700/122706/7321/5707/991/51807/8697/5690/9212/347688/5717/9491/23198/7277/143471/5706/10381/5705/10197/6232/332/1780/8881/1781/7316/10213/5709/5695/5501/8655/5714/51433/9861/79902/3796/5715/5519/5711/5701/5688/1062/699/5687/7846/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/51143/5702/51529/7324/5719/64682/29945/10393/11004/9232/5704/6233/5527/51434/5716/701/7514/7311/9184/5518/25906/10383/5347/84790/84643/29882/6396/5694/9793/10726/81930/55746/5693/5721/140735/5696/7280/5691/7314/996/5515/1778/5516 109 Avian_infectious_bronchitis_virus R-HSA-68882 Mitotic Anaphase 113/2292 201/10654 2.659008841918986e-27 3.405576709073163e-26 1.5582653031083938e-26 4000/5718/5689/5905/11130/5684/5903/5720/11065/5682/246184/1783/1058/5700/122706/7321/5707/991/51807/8697/5690/9212/347688/5717/9491/23198/7277/143471/5706/10381/5705/10197/6232/332/7443/1780/8881/1781/7316/10213/5709/5695/5501/8655/5714/51433/9861/79902/3796/5715/5519/5711/5701/5688/1062/699/5687/7846/5685/5683/7444/5698/5708/5692/5686/5713/119504/5699/5710/51143/5702/51529/7324/5719/64682/29945/10393/11004/9232/23592/5704/6233/5527/51434/5716/701/7514/7311/9184/5518/25906/10383/5347/84790/84643/29882/6396/5694/9793/10726/81930/55746/5693/5721/140735/5696/7280/5691/7314/996/5515/1778/5516 113 Avian_infectious_bronchitis_virus R-HSA-376176 Signaling by ROBO receptors 119/2292 218/10654 4.0329165830963856e-27 5.116042751127986e-26 2.3409109790604587e-26 6158/5718/5689/6138/6144/25/55740/6203/5684/9349/4736/7852/5720/6194/6191/6128/5682/51121/6132/6147/10298/6129/4690/6217/5700/122706/5707/6230/6222/6152/5690/6136/6125/5717/9491/23198/51065/6154/6141/26986/143471/6202/5706/5705/3670/10197/6232/2935/6160/7316/6155/10213/5709/6175/9978/6218/5695/6209/5714/6714/6231/6229/11224/6205/9861/6130/5715/6142/5711/6204/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/1981/7408/140801/6156/5699/6143/5710/6181/6124/5702/998/8453/6207/5719/10487/6654/5704/6233/5716/7311/6223/387/6188/6189/6135/6201/5694/9045/6187/6168/5693/6208/5721/6137/5696/5691/6122/7314/6387 119 Avian_infectious_bronchitis_virus R-HSA-2555396 Mitotic Metaphase and Anaphase 113/2292 202/10654 4.790902663976481e-27 6.020266366430823e-26 2.754650091799784e-26 4000/5718/5689/5905/11130/5684/5903/5720/11065/5682/246184/1783/1058/5700/122706/7321/5707/991/51807/8697/5690/9212/347688/5717/9491/23198/7277/143471/5706/10381/5705/10197/6232/332/7443/1780/8881/1781/7316/10213/5709/5695/5501/8655/5714/51433/9861/79902/3796/5715/5519/5711/5701/5688/1062/699/5687/7846/5685/5683/7444/5698/5708/5692/5686/5713/119504/5699/5710/51143/5702/51529/7324/5719/64682/29945/10393/11004/9232/23592/5704/6233/5527/51434/5716/701/7514/7311/9184/5518/25906/10383/5347/84790/84643/29882/6396/5694/9793/10726/81930/55746/5693/5721/140735/5696/7280/5691/7314/996/5515/1778/5516 113 Avian_infectious_bronchitis_virus R-HSA-5387390 Hh mutants abrogate ligand secretion 51/2292 59/10654 2.0666150924042965e-26 2.572646077647218e-25 1.177147209544602e-25 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/84447/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 51 Avian_infectious_bronchitis_virus R-HSA-202424 Downstream TCR signaling 70/2292 98/10654 3.2781315758340016e-26 4.0430289435286024e-25 1.8499397489355625e-25 5295/8454/1147/5718/5689/8945/5684/3635/5290/5720/4790/6885/5682/5700/122706/7321/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/7335/5970/4792/5714/9861/7322/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5728/5699/5710/5702/5719/7189/5704/6233/5716/7311/3932/5296/7334/5694/3551/5693/5721/5696/997/5691/7314 70 Avian_infectious_bronchitis_virus R-HSA-983189 Kinesins 50/2292 59/10654 4.391294232576286e-25 5.366242126414324e-24 2.4553929122758762e-24 55582/3831/113220/9371/64837/3797/11127/51807/9585/23095/347688/29127/3798/3832/7277/10381/55605/23303/285643/3796/26153/124602/10112/1062/64147/7846/55614/146909/89953/56992/547/90990/3834/11004/3835/23046/55083/147700/10749/3833/3799/10383/24137/84790/84643/9493/22920/81930/7280/221458 50 Avian_infectious_bronchitis_virus R-HSA-5678895 Defective CFTR causes cystic fibrosis 51/2292 61/10654 5.281317013780265e-25 6.395194783959376e-24 2.9262033980658125e-24 5718/5689/5684/5720/5682/5700/122706/5707/79139/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Avian_infectious_bronchitis_virus R-HSA-9614085 FOXO-mediated transcription 53/2292 65/10654 6.61839395646059e-25 7.942072747752708e-24 3.633997250631278e-24 2308/27113/857/2290/2309/57060/10018/4802/2660/7532/207/10971/4303/23410/1027/7295/2810/4287/6720/7534/847/5934/114907/4800/5443/1026/901/84676/4089/8850/1647/9314/10370/1387/4088/2908/10628/10000/6794/2033/4852/4801/3630/3066/3065/6648/4087/208/604/23411/25942/7529/10891 53 Avian_infectious_bronchitis_virus R-HSA-68949 Orc1 removal from chromatin 56/2292 71/10654 7.046631714965033e-25 8.380458432440556e-24 3.8345862433879274e-24 8454/5718/1017/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/890/84515/5714/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 56 Avian_infectious_bronchitis_virus R-HSA-5610787 Hedgehog 'off' state 75/2292 113/10654 8.76404774670374e-25 1.033071822885786e-23 4.7269526272393726e-24 8454/5718/5689/8945/5684/5720/2735/5682/5700/122706/5707/11127/1452/5690/5717/9491/23198/6500/112/7277/143471/114/5706/10381/5705/10197/108/113/7316/10213/5709/9978/5695/8650/111/107/5714/9861/5715/5711/2932/5701/5688/5687/7846/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/83737/5719/5704/6233/5716/7311/10383/23322/84790/196883/115/5694/8481/5693/5721/5696/7280/109/5691/7314 75 Avian_infectious_bronchitis_virus R-HSA-5683057 MAPK family signaling cascades 141/2292 294/10654 1.892888813590747e-24 2.2116911400902413e-23 1.0119876482631972e-23 5718/2308/818/5689/27161/3725/5684/4893/6464/6711/5720/1437/3667/6712/2309/5682/1844/2904/5747/153090/5700/10642/3815/122706/5707/8844/10048/7094/5690/57690/5594/2069/5717/9491/3315/23198/27327/409/5908/3082/7414/143471/5706/2064/5921/5705/10197/3337/192670/8550/8452/7316/10213/5709/9978/1950/5695/8315/4233/983/5597/84078/57731/5714/6714/4609/9861/5715/6710/5519/5711/5701/5688/5159/3567/5687/3558/3717/2247/5685/5683/5698/5708/5692/5686/5713/2335/2534/408/5699/1445/5710/2264/8555/5702/192669/998/2066/6708/5894/8556/896/5719/23112/6654/5704/6233/5527/2885/6709/51332/5716/7514/7311/8826/5518/1956/60/1843/4343/3845/5694/3265/26523/369/4763/7297/5781/8202/3569/5693/5721/5696/5691/5245/7529/5156/7314/5595/5515/5516 141 Avian_infectious_bronchitis_virus R-HSA-202403 TCR signaling 77/2292 119/10654 2.4248617379327425e-24 2.8086224651534025e-23 1.2851212322773986e-23 5295/8454/1147/5718/5689/8945/55740/5684/3635/5290/5720/5335/4790/6885/5682/4690/5700/122706/7321/5707/5690/5717/9491/23198/6500/143471/5706/5705/5788/10197/7316/10213/5709/5695/7335/5970/4792/5714/9861/7322/5715/5711/5701/5688/5687/23291/5685/5683/55824/5698/5708/5692/5686/5713/7408/5728/5699/1445/5710/5702/5719/7189/5704/6233/5716/7311/3932/5296/7334/5694/3551/5693/5721/5696/997/5691/7314 77 Avian_infectious_bronchitis_virus R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 45/2292 51/10654 2.976697770764599e-24 3.418070198843488e-23 1.5639818595941044e-23 5718/5689/5684/1728/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/5694/5693/5721/5696/5691 45 Avian_infectious_bronchitis_virus R-HSA-5632684 Hedgehog 'on' state 62/2292 85/10654 3.6541597249723e-24 4.160120302276157e-23 1.9035164019423858e-23 57154/5718/5689/5684/5720/2735/5682/5700/122706/5707/11127/22873/1452/5690/5717/9491/23198/409/79577/143471/5706/5705/10197/64750/8452/7316/10213/5709/9978/5695/8650/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/408/5699/5710/5702/83737/5719/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 62 Avian_infectious_bronchitis_virus R-HSA-5688426 Deubiquitination 141/2292 297/10654 6.6093685684305744e-24 7.460744858601292e-23 3.413759501446301e-23 9960/5718/23358/5689/5684/8295/5720/3607/23326/10617/221937/6885/5682/90865/2648/79594/5700/10474/122706/7321/5707/991/51377/8237/4738/5690/55611/2625/9817/4303/51720/5717/9491/57646/23198/63967/409/6478/1080/4086/3091/143471/5706/5705/4287/55031/27005/10197/7706/86/64750/580/8239/7316/10213/5709/993/5695/890/25862/80124/4792/983/84132/5714/4092/8678/2099/9100/1643/79589/4609/7415/9861/4194/4089/5715/8850/7128/5711/5701/5688/9097/5687/7046/6502/4088/5685/5683/5698/5708/9146/5692/5686/5713/2033/408/5728/5699/8312/5710/10454/5702/7157/8900/9958/4087/63891/5719/84749/7189/57599/5704/6233/5716/672/7048/7311/55593/367/6881/79184/51616/114548/78990/387/60/7040/7345/1540/5694/7874/5693/10254/5721/5696/5691/5886/7314/4193/7528 141 Avian_infectious_bronchitis_virus R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 49/2292 59/10654 8.230978985902355e-24 9.21316303295961e-23 4.215600913611202e-23 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/84515/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 49 Avian_infectious_bronchitis_virus R-HSA-162906 HIV Infection 119/2292 233/10654 9.48842189524017e-24 1.0532148303716589e-22 4.8191195415298766e-23 6884/5718/6875/5689/5905/8945/3837/5684/5903/8065/7852/5720/902/7175/5682/9631/3159/5700/122706/5707/5430/6874/5690/7520/6878/5717/4869/9491/23198/6500/6749/143471/5706/5705/10197/7316/10213/5709/9978/5695/6872/292/4331/3055/4836/9397/5714/4927/8148/9861/79902/6879/9150/5715/5711/23327/5701/5688/54457/8812/5687/83860/5685/5683/5698/5708/5692/2965/5686/128866/5713/2534/5699/905/5710/2068/5702/2071/6873/5719/5704/6233/2968/5716/7514/1025/9844/7311/9972/6881/3932/51616/6880/6908/8021/7251/11198/6396/375/904/6883/5694/1104/51497/2547/6882/138474/1022/55746/5693/1234/5721/5696/8178/5691/8480/6877/940/7314 119 Avian_infectious_bronchitis_virus R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic 108/2292 202/10654 9.858680016094795e-24 1.0852695687139062e-22 4.965790108150402e-23 55582/3831/84364/6811/22820/400/113220/5321/11014/9371/64837/11258/3797/1783/11127/51014/51807/9585/23095/93661/5050/347688/29127/3798/5861/55860/830/3832/7277/10381/9950/55605/10671/1780/9554/377/1781/9570/8398/8655/1315/23303/84516/1639/832/285643/10121/55738/3796/26153/81876/10226/124602/10112/11316/636/1062/6836/64147/11015/7846/55614/146909/89953/56992/547/8729/23423/90990/10972/51226/51143/1314/10540/381/3834/11004/9276/3835/23046/55083/147700/10749/3833/3799/10383/24137/84790/84643/378/10945/9493/375/26286/22920/81930/26958/140735/7280/10959/10652/54732/221458/829/51164/1778/22818/372 108 Avian_infectious_bronchitis_virus R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 44/2292 50/10654 1.239947896181164e-23 1.353779178453533e-22 6.194390266513322e-23 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/5694/5693/5721/5696/5691 44 Avian_infectious_bronchitis_virus R-HSA-4608870 Asymmetric localization of PCP proteins 51/2292 64/10654 3.832792791633792e-23 4.1506341450863506e-22 1.8991758890508905e-22 57154/5718/5689/5684/5720/5682/5700/122706/5707/1856/5690/5717/9491/23198/143471/5706/5705/10197/64750/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Avian_infectious_bronchitis_virus R-HSA-9009391 Extra-nuclear estrogen signaling 57/2292 77/10654 7.491358868698731e-23 8.047169365408637e-22 3.682085556007271e-22 5295/2788/596/5590/4893/6464/857/5290/54331/2309/5747/59345/2770/207/1903/5594/2069/1027/3315/10681/51764/94235/4318/4313/1950/55970/4314/2792/346562/6714/2099/2793/10000/3320/2785/4846/595/2783/2784/2782/2786/2771/208/7514/1385/2353/1956/5296/3845/3276/3265/3480/2791/2773/5595/2790/2787 57 Avian_infectious_bronchitis_virus R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 40/2292 44/10654 8.3395779466727e-23 8.88665425997443e-22 4.0662026367355736e-22 23368/834/27113/79370/9540/8793/55240/58484/3486/355/55367/472/8794/332/64065/5366/124446/8797/84883/147923/5876/1387/51499/843/94241/7157/8626/604/63970/7161/839/581/7159/637/317/10397/8795/665/5875/27166 40 Avian_infectious_bronchitis_virus R-HSA-380108 Chemokine receptors bind chemokines 48/2292 59/10654 1.3741582948879035e-22 1.4526816260243551e-21 6.646931100585598e-22 729230/57007/10803/10663/7852/6351/6374/1237/1230/2919/3577/3576/5196/6360/3579/2920/2826/2921/1236/6352/6376/6348/6354/3627/6346/6364/10563/6370/58191/1524/643/10850/2829/1233/6372/6366/5473/4283/6363/6373/2833/6347/6357/6356/56477/1232/1234/6387 48 Avian_infectious_bronchitis_virus R-HSA-5358346 Hedgehog ligand biogenesis 51/2292 65/10654 1.4106862768297858e-22 1.4795544257773816e-21 6.769891042556537e-22 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/84447/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 51 Avian_infectious_bronchitis_virus R-HSA-2559583 Cellular Senescence 103/2292 195/10654 3.7567327796183304e-22 3.909350048790325e-21 1.788773256084715e-21 1912/1017/3725/9134/1019/5601/11065/4790/5606/3159/246184/7290/1029/7027/7321/2146/10111/8535/6045/8697/57690/5594/1027/27327/80012/898/5931/7295/5925/1051/472/79813/192670/3576/8550/8881/29855/7316/2114/1869/890/6774/5970/1026/1911/6667/51433/4194/1031/5598/3552/5928/1432/10524/84733/4683/5602/23512/1021/119504/57332/6195/25842/192669/7157/8900/51529/23135/7324/64682/29945/10393/8091/23112/5609/6233/51434/2353/1030/51343/6196/7311/25906/57634/4343/8726/6197/29882/5599/648/5600/23466/26523/3456/2113/3569/10919/7314/23523/996/6015/5595/4193 103 Avian_infectious_bronchitis_virus R-HSA-5689880 Ub-specific processing proteases 111/2292 220/10654 1.1215983980801633e-21 1.1581155552269595e-20 5.299106262655362e-21 9960/5718/23358/5689/5684/8295/5720/23326/6885/5682/90865/2648/79594/5700/10474/122706/5707/991/8237/5690/55611/2625/9817/4303/5717/9491/57646/23198/63967/409/6478/1080/4086/3091/143471/5706/5705/55031/27005/10197/64750/8239/7316/10213/5709/993/5695/890/25862/4792/84132/5714/4092/8678/9100/1643/79589/4609/9861/4194/4089/5715/5711/5701/5688/9097/5687/7046/6502/4088/5685/5683/5698/5708/9146/5692/5686/5713/408/5728/5699/8312/5710/10454/5702/7157/8900/9958/4087/63891/5719/84749/7189/57599/5704/6233/5716/7311/367/6881/51616/1540/5694/7874/5693/10254/5721/5696/5691/7314/4193 111 Avian_infectious_bronchitis_virus R-HSA-5358351 Signaling by Hedgehog 85/2292 149/10654 2.142966774812011e-21 2.195716726191999e-20 1.0046783502964814e-20 8454/57154/5718/5689/8945/5684/5720/2735/5682/5700/122706/5707/11127/22873/1452/5690/5717/9491/23198/6500/409/79577/112/7277/143471/114/5706/10381/5705/10197/108/64750/113/8452/84447/7316/10213/5709/9978/5695/8650/111/107/5714/7415/9861/5715/5711/2932/5701/5688/5687/7846/5685/5683/5698/5708/5692/5686/5713/408/5699/5710/5702/83737/5719/5704/6233/5716/7311/10383/6469/23322/84790/196883/115/5694/8481/5693/5721/5696/7280/109/5691/7314 85 Avian_infectious_bronchitis_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 97/2292 182/10654 2.6585437267126824e-21 2.7031910259399185e-20 1.2368797250033294e-20 1912/7020/7150/5905/6670/5903/7068/7175/1487/5241/3622/9631/5468/7021/1029/7486/1788/9112/8535/51564/1786/6045/9212/51588/4869/3090/80012/7153/6613/332/10210/28996/1655/5970/4792/3190/6996/9759/9612/8856/1911/6790/641/6672/5111/2099/4927/79902/9656/7341/1387/84733/10401/1616/2908/2033/23512/57332/7022/142/7428/3066/3065/7157/1107/668/7329/5987/5371/8924/672/115426/7158/10155/367/9972/10499/6612/9063/7155/25942/8021/9641/6117/6294/6396/648/11315/55746/8648/7421/8480/10891/7508/6015/4193/8554 97 Avian_infectious_bronchitis_virus R-HSA-162909 Host Interactions of HIV factors 77/2292 129/10654 3.700117629304434e-21 3.733755062298111e-20 1.7084275178367363e-20 5718/5689/5905/8945/3837/5684/5903/8065/5720/7175/5682/9631/3159/5700/122706/5707/5690/5717/4869/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/292/3055/5714/4927/9861/79902/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/2534/5699/5710/5702/5719/5704/6233/5716/7514/1025/9844/7311/9972/3932/8021/6396/375/904/5694/1104/55746/5693/5721/5696/5691/8480/940/7314 77 Avian_infectious_bronchitis_virus R-HSA-9607240 FLT3 Signaling 125/2292 267/10654 1.1773900475237254e-20 1.179160558873385e-19 5.395400376068358e-20 5295/54106/5718/818/5689/5684/4893/6464/6711/5290/5720/1437/3667/6712/5682/1844/2904/5747/153090/5700/3815/122706/5707/8844/10048/7094/5690/5594/2069/5717/9491/23198/409/5908/3082/7414/143471/5706/2064/57761/5921/5705/10197/8452/6776/7316/10213/5709/9978/1950/5695/8315/5289/4233/3055/84078/57731/5714/6714/9861/5715/6710/5519/5711/5701/5688/5159/3567/5687/3558/3717/2247/5685/5683/5698/5708/5692/5686/5713/2335/2534/408/5699/1445/5710/2264/5702/2066/6708/5894/5719/208/6654/5704/6233/5527/2885/6709/51332/5716/7311/8826/5518/1956/60/5296/1843/3845/6777/5694/3265/369/4763/5781/5693/5721/5696/5691/5245/7529/5156/7314/5595/5515/5516 125 Avian_infectious_bronchitis_virus R-HSA-2990846 SUMOylation 98/2292 188/10654 1.374635659521957e-20 1.3664288794651095e-19 6.252270595940402e-20 1912/7020/7150/5905/6670/5903/7068/29843/7175/1487/5241/3622/9631/5468/7021/1029/7486/1788/9112/8535/51564/1786/6045/9212/51588/4869/3090/80012/7153/6613/332/10210/28996/1655/5970/4792/3190/6996/9759/9612/8856/1911/6790/641/6672/5111/2099/4927/79902/9656/7341/1387/84733/10401/1616/2908/2033/23512/57332/7022/142/7428/3066/3065/7157/1107/668/7329/5987/5371/8924/672/115426/7158/10155/367/9972/10499/6612/9063/7155/25942/8021/9641/6117/6294/6396/648/11315/55746/8648/7421/8480/10891/7508/6015/4193/8554 98 Avian_infectious_bronchitis_virus R-HSA-420499 Class C/3 (Metabotropic glutamate/pheromone receptors) 35/2292 38/10654 1.5139844418292027e-20 1.4937979826048133e-19 6.835064263696751e-20 2913/50833/338398/5726/2916/259293/259287/2550/50836/50832/846/2918/259294/259290/2912/259295/9568/54429/80834/259292/50834/259285/50838/2914/2917/50831/50839/83756/80835/259296/259289/50835/50840/259286/50837 35 Avian_infectious_bronchitis_virus R-HSA-8943724 Regulation of PTEN gene transcription 47/2292 61/10654 2.6034764828055226e-20 2.549875496394821e-19 1.1667282380374596e-19 1912/3725/6591/8841/5468/1822/23186/2146/5978/9112/9219/8535/51564/6045/5594/84232/80012/5931/1911/1108/57167/2122/7101/10014/1958/5928/84733/57459/54815/23512/57332/6615/3066/3065/7157/1107/23028/10542/2475/57504/1386/8726/648/23466/53615/6015/5595 47 Avian_infectious_bronchitis_virus R-HSA-351202 Metabolism of polyamines 46/2292 59/10654 2.78955747013563e-20 2.712182883372744e-19 1.2409940647011372e-19 5718/5689/5684/1728/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/6303/5694/5693/5721/5696/5691 46 Avian_infectious_bronchitis_virus R-HSA-1236974 ER-Phagosome pathway 57/2292 83/10654 3.04720335504066e-20 2.9412136731262025e-19 1.345790040098049e-19 1147/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10333/10197/7099/4615/9554/7316/10213/5709/5695/7096/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/695/5719/5704/6233/5716/7311/5694/7097/3551/5693/5721/5696/5691/7314 57 Avian_infectious_bronchitis_virus R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 69/2292 112/10654 3.542002466767013e-20 3.3942066803839294e-19 1.5530628006498303e-19 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/8666/6129/6217/6230/6222/1983/6152/6136/8668/8667/6125/51065/6154/8662/6141/10480/6202/6232/6160/6155/8661/6175/6218/9669/6209/6231/6229/11224/6205/6130/6142/6204/8894/1981/140801/6156/6143/6181/6124/6207/6233/1975/7311/6223/3646/51386/6188/6189/8665/6135/6201/9045/6187/6168/6208/6137/6122 69 Avian_infectious_bronchitis_virus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 31/2292 32/10654 4.4575575215684195e-20 4.241047584806525e-19 1.940545718036177e-19 892/7027/3726/54778/7316/1875/1024/6667/5933/4092/4609/4089/22938/60436/8812/7050/4088/1874/905/3065/4087/6233/1025/1030/7311/25937/904/23439/7314/4221/5054 31 Avian_infectious_bronchitis_virus R-HSA-68867 Assembly of the pre-replicative complex 50/2292 68/10654 5.504409778120263e-20 5.199910513798717e-19 2.3792857495570234e-19 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/1869/5695/84515/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Avian_infectious_bronchitis_virus R-HSA-5685938 HDR through Single Strand Annealing (SSA) 34/2292 37/10654 6.56098600768465e-20 6.154389691715461e-19 2.816019939547378e-19 6118/80010/25/83990/5888/9156/5883/1763/7486/10111/5982/545/472/580/11073/116028/641/6119/3364/10524/4683/144715/5985/84126/5984/2067/672/5932/7156/5983/6117/5884/5810/83695 34 Avian_infectious_bronchitis_virus R-HSA-72689 Formation of a pool of free 40S subunits 64/2292 101/10654 9.774214594112016e-20 9.10437331423581e-19 4.165822782473947e-19 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/8666/6129/6217/6230/6222/6152/6136/8668/8667/6125/51065/6154/8662/6141/10480/6202/6232/6160/6155/8661/6175/6218/6209/6231/6229/11224/6205/6130/6142/6204/140801/6156/6143/6181/6124/6207/6233/7311/6223/3646/51386/6188/6189/8665/6135/6201/9045/6187/6168/6208/6137/6122 64 Avian_infectious_bronchitis_virus R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 68/2292 111/10654 1.0374349327295313e-19 9.596273127748165e-19 4.390897851245604e-19 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/8666/6129/6217/6230/6222/6152/6136/8668/8667/6125/51065/6154/8662/6141/10480/26986/6202/6232/6160/6155/8661/6175/6218/6209/6231/6229/11224/6205/6130/6142/6204/8894/1981/140801/6156/6143/6181/6124/6207/6233/1975/7311/6223/3646/51386/6188/6189/8665/6135/6201/9045/6187/6168/6208/6137/6122 68 Avian_infectious_bronchitis_virus R-HSA-5684996 MAPK1/MAPK3 signaling 118/2292 255/10654 4.677968260722188e-19 4.297278429849624e-18 1.9662748624015588e-18 5718/818/5689/5684/4893/6464/6711/5720/1437/3667/6712/5682/1844/2904/5747/153090/5700/3815/122706/5707/8844/10048/7094/5690/5594/2069/5717/9491/23198/409/5908/3082/7414/143471/5706/2064/5921/5705/10197/8452/7316/10213/5709/9978/1950/5695/8315/4233/983/84078/57731/5714/6714/9861/5715/6710/5519/5711/5701/5688/5159/3567/5687/3558/3717/2247/5685/5683/5698/5708/5692/5686/5713/2335/2534/408/5699/1445/5710/2264/5702/2066/6708/5894/5719/6654/5704/6233/5527/2885/6709/51332/5716/7311/8826/5518/1956/60/1843/3845/5694/3265/369/4763/7297/5781/3569/5693/5721/5696/5691/5245/7529/5156/7314/5595/5515/5516 118 Avian_infectious_bronchitis_virus R-HSA-72613 Eukaryotic Translation Initiation 70/2292 119/10654 7.404345090753044e-19 6.709243306723167e-18 3.0699003276376746e-18 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/8666/6129/6217/6230/6222/1983/6152/6136/8668/8667/6125/51065/6154/8662/6141/10480/26986/6202/6232/6160/6155/8661/6175/6218/9669/6209/6231/6229/11224/6205/6130/6142/6204/8894/1981/140801/6156/6143/6181/6124/6207/6233/1975/7311/6223/3646/51386/6188/6189/8665/6135/6201/9045/6187/6168/6208/6137/6122 70 Avian_infectious_bronchitis_virus R-HSA-72737 Cap-dependent Translation Initiation 70/2292 119/10654 7.404345090753044e-19 6.709243306723167e-18 3.0699003276376746e-18 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/8666/6129/6217/6230/6222/1983/6152/6136/8668/8667/6125/51065/6154/8662/6141/10480/26986/6202/6232/6160/6155/8661/6175/6218/9669/6209/6231/6229/11224/6205/6130/6142/6204/8894/1981/140801/6156/6143/6181/6124/6207/6233/1975/7311/6223/3646/51386/6188/6189/8665/6135/6201/9045/6187/6168/6208/6137/6122 70 Avian_infectious_bronchitis_virus R-HSA-199977 ER to Golgi Anterograde Transport 83/2292 154/10654 8.304971390934479e-19 7.47447425184103e-18 3.42004156141612e-18 2348/84364/6811/23256/22820/6711/11014/11258/6712/1783/4253/51014/51807/286/2801/93661/347688/5861/55860/830/7277/10381/10671/1780/1604/9554/377/1781/9570/22872/966/8655/1315/11196/84516/1639/832/57731/81562/10282/10121/55738/8615/6710/81876/11316/11015/7846/8729/23423/10972/51226/51143/1314/3630/10540/381/6708/9276/287/6709/51332/9871/10383/84790/378/10945/6396/375/26286/1453/288/26958/140735/7280/10959/10652/54732/829/51164/1778/22818/372 83 Avian_infectious_bronchitis_virus R-HSA-4086400 PCP/CE pathway 59/2292 92/10654 1.1406071507829398e-18 1.0196568623106549e-17 4.665570754527179e-18 57154/5718/5689/5684/5720/5682/5700/122706/5707/1856/5690/1212/5717/9491/23198/409/143471/5706/5705/10197/64750/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/1855/5716/1857/7311/1213/387/1211/5694/5693/5721/5696/6259/5691/7314 59 Avian_infectious_bronchitis_virus R-HSA-195721 Signaling by WNT 141/2292 331/10654 1.6455725913524256e-18 1.461268461120954e-17 6.6862212659161716e-18 2788/8454/57154/5718/27123/9070/5689/27161/51176/8945/5684/8295/857/5720/54331/6662/7015/6885/1487/6597/5682/1499/59345/51701/864/1459/4772/5700/122706/5707/1856/207/1454/1452/5690/1212/57690/5717/5929/9491/23198/6500/10681/27327/409/79577/6736/51764/1460/94235/143471/5706/3708/5705/10197/6657/192670/7534/64750/8452/5530/7316/10213/5709/9978/5695/55970/1457/3709/2792/5714/4609/9861/5715/5519/5711/2932/5701/10524/5688/1387/2793/5687/1455/5685/5683/5698/5708/5692/5686/5713/2033/54894/2785/5534/5699/2783/2784/8312/5710/2782/5702/192669/3065/2786/5719/23112/208/57680/5704/6233/5527/1855/5716/1857/7514/23072/7311/5518/1213/387/3710/1211/331/4343/3845/6659/5694/26523/5693/5721/2791/5696/6259/5691/7314/4221/2790/5515/2787/5516 141 Avian_infectious_bronchitis_virus R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 34/2292 39/10654 3.061495917295993e-18 2.700604345588253e-17 1.2356961562317045e-17 6118/80010/83990/5888/9156/5883/1763/7486/10111/675/5982/545/472/580/11073/116028/641/6119/3364/10524/4683/144715/5985/84126/1111/5984/672/5932/7156/5983/6117/5884/5810/83695 34 Avian_infectious_bronchitis_virus R-HSA-156902 Peptide chain elongation 57/2292 89/10654 4.848507125054772e-18 4.2488233490611557e-17 1.94410361870271e-17 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/1938/6147/6129/1915/6217/6230/6222/6152/6136/6125/51065/6154/6141/6202/6232/6160/6155/6175/6218/6209/6231/6229/11224/6205/6130/6142/6204/140801/6156/6143/6181/6124/6207/6233/7311/6223/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122 57 Avian_infectious_bronchitis_virus R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 42/2292 55/10654 4.972690342804207e-18 4.329165710206015e-17 1.9808652965143695e-17 3303/5241/11258/1783/51807/93661/347688/10294/55860/830/7277/10381/3337/10671/1780/1781/3305/8655/84516/1639/832/10121/7846/2908/3320/51143/3301/10540/3326/3306/367/10383/84790/3304/3312/140735/7280/2288/10728/829/51164/1778 42 Avian_infectious_bronchitis_virus R-HSA-5673001 RAF/MAP kinase cascade 114/2292 249/10654 5.21609730195594e-18 4.511585458574878e-17 2.064333792093294e-17 5718/818/5689/5684/4893/6464/6711/5720/1437/3667/6712/5682/1844/2904/5747/153090/5700/3815/122706/5707/8844/10048/7094/5690/5594/2069/5717/9491/23198/409/5908/3082/7414/143471/5706/2064/5921/5705/10197/8452/7316/10213/5709/9978/1950/5695/8315/4233/84078/57731/5714/6714/9861/5715/6710/5519/5711/5701/5688/5159/3567/5687/3558/3717/2247/5685/5683/5698/5708/5692/5686/5713/2335/2534/408/5699/1445/5710/2264/5702/2066/6708/5894/5719/6654/5704/6233/5527/2885/6709/51332/5716/7311/8826/5518/1956/60/1843/3845/5694/3265/369/4763/5693/5721/5696/5691/5245/7529/5156/7314/5595/5515/5516 114 Avian_infectious_bronchitis_virus R-HSA-5689603 UCH proteinases 62/2292 102/10654 7.613198875999454e-18 6.542439292149209e-17 2.9935770113437585e-17 5718/5689/5684/5720/3607/221937/5682/5700/122706/5707/51377/4738/5690/5717/9491/23198/143471/5706/5705/10197/86/580/7316/10213/5709/5695/5714/4092/9861/5715/5711/5701/5688/5687/7046/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9958/5719/5704/6233/5716/7048/7311/60/7040/7345/5694/5693/5721/5696/5691/7314/7528 62 Avian_infectious_bronchitis_virus R-HSA-69002 DNA Replication Pre-Initiation 55/2292 85/10654 9.364183220905666e-18 7.995571827080991e-17 3.658476440556262e-17 5718/1017/6118/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5422/1869/5695/84515/5714/9861/5715/6119/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/6117/5694/5693/5721/5696/5691/7314 55 Avian_infectious_bronchitis_virus R-HSA-390466 Chaperonin-mediated protein folding 59/2292 95/10654 1.1013971693990578e-17 9.344337768404747e-17 4.275621596259166e-17 2788/10694/26224/9134/8841/54331/59345/1459/2770/51807/8237/10575/10681/898/51764/1460/7277/94235/10381/10517/7203/10576/908/55970/6774/1457/2792/26272/346562/6468/2793/26270/6950/7846/2785/55294/2783/26190/2784/10238/2782/7157/2786/2771/10574/10564/10383/60/54461/84790/22948/26234/10693/2791/7280/84261/2773/2790/2787 59 Avian_infectious_bronchitis_virus R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 35/2292 42/10654 1.919186529050691e-17 1.6179471244908357e-16 7.403124585745171e-17 6118/80010/83990/5888/9156/5883/1763/7486/10111/675/5982/545/472/580/11073/116028/641/6119/3364/10524/4683/144715/5985/84126/1111/5984/79728/672/5932/7156/5983/6117/5884/5810/83695 35 Avian_infectious_bronchitis_virus R-HSA-69231 Cyclin D associated events in G1 36/2292 44/10654 2.1244199344061122e-17 1.7685795953930883e-16 8.092362776454861e-17 8454/25/894/1019/902/1029/7027/1027/6500/5925/5934/7316/1869/1875/4331/1026/5933/6714/1031/5519/4067/3717/6502/1021/1874/595/896/6233/1030/7311/5518/1022/1028/7314/5515/5516 36 Avian_infectious_bronchitis_virus R-HSA-69236 G1 Phase 36/2292 44/10654 2.1244199344061122e-17 1.7685795953930883e-16 8.092362776454861e-17 8454/25/894/1019/902/1029/7027/1027/6500/5925/5934/7316/1869/1875/4331/1026/5933/6714/1031/5519/4067/3717/6502/1021/1874/595/896/6233/1030/7311/5518/1022/1028/7314/5515/5516 36 Avian_infectious_bronchitis_virus R-HSA-168898 Toll-like Receptor Cascades 81/2292 155/10654 2.5515586478203457e-17 2.1109789558364597e-16 9.659054966250278e-17 54106/8454/1147/3665/3725/8945/5601/351/81793/4790/6885/5606/7184/7321/5336/3684/5594/4214/6500/8411/10333/841/7099/4615/7098/7100/338/7323/7316/7335/5970/4792/7096/5289/4793/6279/8651/5775/3146/7322/5519/5598/1432/4208/23291/5602/6195/57162/10454/6288/695/3654/7189/6285/5609/6233/51311/10010/1385/2353/6196/7311/1759/5518/1386/9641/6197/5599/5600/7334/7097/3929/3551/5781/57161/51231/51284/7314/5595/5515/5516 81 Avian_infectious_bronchitis_virus R-HSA-8939211 ESR-mediated signaling 104/2292 223/10654 3.1175347543458324e-17 2.5633063535732396e-16 1.172873699003403e-16 5295/2788/3727/27161/3725/3838/596/5590/4893/6464/857/5290/54331/5241/2309/4435/5747/59345/5430/2770/207/1903/2625/57690/5594/2069/1027/3315/10681/27327/51523/51764/94235/4318/5481/192670/200845/4313/1950/865/55970/5469/1655/4314/6667/2792/346562/6714/2099/4609/7391/8850/10524/1387/2793/10000/3320/2033/2785/4846/595/2783/4602/2784/8312/2782/192669/3065/2066/861/23028/2786/23112/2771/208/10498/3326/7514/1385/1025/2353/10499/1386/6908/1956/5296/4343/3845/904/3276/3265/26523/8202/8648/3480/2791/2288/2773/10728/5595/2790/2787/7528/6387 104 Avian_infectious_bronchitis_virus R-HSA-5619084 ABC transporter disorders 51/2292 77/10654 3.307986094112653e-17 2.7032131762932845e-16 1.236889860181612e-16 5718/5689/5684/5720/5682/5700/122706/5707/79139/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Avian_infectious_bronchitis_virus R-HSA-68886 M Phase 157/2292 395/10654 4.5475540976698015e-17 3.693501254936692e-16 1.6900088719838352e-16 10844/4000/115106/5718/5689/5905/11130/22995/5684/5903/5720/11065/7175/11258/5682/22981/9631/246184/7531/1459/1783/1058/5700/122706/7321/5707/991/203068/54801/51807/7532/1454/2801/8697/5690/9212/5594/347688/5717/9491/23198/5861/5925/1460/7277/143471/5706/10381/5705/10197/6232/332/7443/1780/8881/1781/7316/10213/5709/891/5695/5501/8655/1457/983/1639/8548/5714/4927/10121/51433/9861/79902/3796/8615/5715/5519/81876/5711/5701/5688/10112/1062/699/5687/7846/5685/7283/5683/7444/5698/5708/3320/5692/5686/5713/80097/119504/5699/23397/5710/51143/5702/10540/51529/7324/5719/64682/29945/10393/11004/9232/23592/5704/6233/5527/51434/5716/701/7514/7311/9184/54930/9972/5518/25906/10383/55835/5347/84790/8021/84643/9493/29882/6396/9662/5694/1453/9793/10726/6418/81930/55746/8481/5693/5721/140735/5696/7280/5691/8480/7314/996/5595/5515/1778/5516 157 Avian_infectious_bronchitis_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 40/2292 53/10654 6.418834376650242e-17 5.181749933150377e-16 2.3709761429540604e-16 23368/27113/596/10018/7531/1029/7027/842/7532/207/10971/5594/7533/2810/841/7534/1869/8655/6774/54205/4836/5366/598/836/10000/5534/7157/8626/208/7161/331/581/5599/7159/637/317/140735/7529/578/5595 40 Avian_infectious_bronchitis_virus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 58/2292 95/10654 6.602510036655542e-17 5.297917692063363e-16 2.4241301910105e-16 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/6152/6136/6125/51065/6154/6141/26986/6202/6232/2935/6160/6155/6175/6218/6209/6231/6229/11224/6205/6130/6142/6204/1981/140801/6156/6143/6181/6124/6207/6233/7311/6223/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122 58 Avian_infectious_bronchitis_virus R-HSA-73894 DNA Repair 138/2292 334/10654 8.870134705603428e-17 7.074861932852555e-16 3.237193819441781e-16 10450/9318/8467/1017/6118/2176/80010/25/3838/4436/83990/902/5888/9156/2074/5883/1763/328/7486/5430/10111/4913/7320/51588/7520/51720/2956/675/7515/5982/63967/5531/51548/4292/11200/545/472/6613/7706/7336/51567/86/580/11073/5591/8450/54778/7316/9978/11201/116028/890/6996/4331/64708/641/5111/9100/1643/7415/5395/10980/64421/9656/6119/51455/3364/7341/10524/4683/10401/144715/1161/1642/2965/5985/10920/25898/2033/84126/142/7398/2068/1111/10987/2071/7157/8900/5984/4595/7329/4255/9246/79728/8924/57599/6233/2067/51426/2873/2968/672/5932/7158/7311/6047/7318/4968/79184/6612/55247/60/8533/7156/5983/6117/2175/5599/7334/10973/5981/10714/7874/2547/5884/5810/1022/8178/83695/5886/50813/7508/7314/51514/51138/8451/8554/7528 138 Avian_infectious_bronchitis_virus R-HSA-157118 Signaling by NOTCH 107/2292 235/10654 9.13060720341928e-17 7.239267139853858e-16 3.3124195305637613e-16 8454/5718/5689/27161/3725/5684/8841/5720/142678/5682/2648/9734/892/7027/5700/5707/23462/207/51564/4904/5690/57690/5717/9491/6500/27327/409/3091/51548/10013/5706/5705/10197/192670/7534/7316/10213/5709/9978/1950/1869/4854/9611/5695/8650/9759/9612/1024/5714/6772/4609/11060/9861/10014/5715/22938/8850/5711/5701/5688/1387/5687/4088/5685/5683/5698/5708/59/5692/5686/26508/5713/2033/408/4855/595/55294/5699/5710/5702/192669/3066/3065/7157/83737/861/5719/23112/9794/5704/6233/5716/1385/7311/1956/4343/5694/26523/3516/4851/5693/5663/5721/5696/10959/5691/7314 107 Avian_infectious_bronchitis_virus R-HSA-156842 Eukaryotic Translation Elongation 57/2292 93/10654 9.490126070802396e-17 7.479791672372066e-16 3.422474615381244e-16 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/1938/6147/6129/1915/6217/6230/6222/6152/6136/6125/51065/6154/6141/6202/6232/6160/6155/6175/6218/6209/6231/6229/11224/6205/6130/6142/6204/140801/6156/6143/6181/6124/6207/6233/7311/6223/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122 57 Avian_infectious_bronchitis_virus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 53/2292 84/10654 1.8775443980565414e-16 1.4711112577713606e-15 6.731258244425619e-16 9318/6118/902/7515/5982/6613/7336/86/8450/54778/7316/9978/4331/64708/5111/1643/10980/6119/7341/10401/1642/2965/5985/10920/142/2068/10987/2071/5984/7329/6233/2067/51426/2873/2968/7311/6612/60/8533/5983/6117/7334/5981/10714/1022/5886/50813/7508/7314/51138/8451/8554/7528 53 Avian_infectious_bronchitis_virus R-HSA-192823 Viral mRNA Translation 55/2292 89/10654 1.9470755868481231e-16 1.5166694044922222e-15 6.939715388027475e-16 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/6152/6136/6125/51065/6154/6141/6202/6232/6160/6155/6175/6218/6209/6231/6229/11224/6205/6130/6142/6204/140801/6156/6143/6181/6124/6207/6233/7311/6223/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122 55 Avian_infectious_bronchitis_virus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 60/2292 102/10654 2.3660047701725805e-16 1.832278112715045e-15 8.383823512423037e-16 8454/7124/1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/8600/5690/9039/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/943/7311/5971/958/5694/5693/5721/5696/5691/7314 60 Avian_infectious_bronchitis_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 58/2292 97/10654 2.6069832595309695e-16 2.007226417164885e-15 9.184321918274606e-16 54106/8454/1147/3665/3725/8945/5601/351/4790/6885/5606/5594/4214/6500/8411/7099/4615/7316/7335/5970/4792/5289/4793/3146/5519/5598/1432/4208/23291/5602/6195/57162/10454/6288/3654/7189/6285/5609/6233/51311/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/51284/7314/5595/5515/5516 58 Avian_infectious_bronchitis_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 70/2292 129/10654 2.839153566135845e-16 2.1734210058005435e-15 9.944766574668207e-16 8454/1147/3665/3725/8945/5601/351/4790/6885/5606/7321/5336/3684/5594/4214/6500/10333/841/7099/4615/7323/7316/7335/5970/4792/7096/4793/8651/5775/3146/7322/5519/5598/1432/4208/23291/5602/6195/57162/10454/6288/695/3654/7189/6285/5609/6233/10010/1385/2353/6196/7311/1759/5518/1386/9641/6197/5599/5600/7334/7097/3929/3551/5781/57161/51231/7314/5595/5515/5516 70 Avian_infectious_bronchitis_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 57/2292 95/10654 3.787782321167872e-16 2.8666625294293213e-15 1.3116782081077737e-15 8454/1147/3725/8945/5601/351/4790/6885/5606/5594/4214/6500/10333/7099/4615/7316/7335/5970/4792/7096/4793/8651/3146/5519/5598/1432/4208/23291/5602/6195/57162/10454/6288/695/3654/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/7097/3551/57161/51231/7314/5595/5515/5516 57 Avian_infectious_bronchitis_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 57/2292 95/10654 3.787782321167872e-16 2.8666625294293213e-15 1.3116782081077737e-15 8454/1147/3725/8945/5601/351/4790/6885/5606/5594/4214/6500/10333/7099/4615/7316/7335/5970/4792/7096/4793/8651/3146/5519/5598/1432/4208/23291/5602/6195/57162/10454/6288/695/3654/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/7097/3551/57161/51231/7314/5595/5515/5516 57 Avian_infectious_bronchitis_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 53/2292 85/10654 3.953794697486074e-16 2.9421533726544417e-15 1.3462200116697661e-15 8454/1147/3725/8945/5601/351/81793/4790/6885/5606/5594/4214/6500/4615/7100/7316/7335/5970/4792/4793/3146/5519/5598/1432/4208/23291/5602/6195/57162/10454/6288/3654/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 53 Avian_infectious_bronchitis_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 53/2292 85/10654 3.953794697486074e-16 2.9421533726544417e-15 1.3462200116697661e-15 8454/1147/3725/8945/5601/351/81793/4790/6885/5606/5594/4214/6500/4615/7100/7316/7335/5970/4792/4793/3146/5519/5598/1432/4208/23291/5602/6195/57162/10454/6288/3654/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 53 Avian_infectious_bronchitis_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 53/2292 85/10654 3.953794697486074e-16 2.9421533726544417e-15 1.3462200116697661e-15 8454/1147/3725/8945/5601/351/81793/4790/6885/5606/5594/4214/6500/4615/7100/7316/7335/5970/4792/4793/3146/5519/5598/1432/4208/23291/5602/6195/57162/10454/6288/3654/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 53 Avian_infectious_bronchitis_virus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 23/2292 23/10654 4.114981010913265e-16 3.0282622688046793e-15 1.385620241534621e-15 11065/246184/7321/991/8697/8881/7316/891/983/51433/119504/51529/7324/64682/29945/10393/6233/51434/7311/25906/29882/7314/996 23 Avian_infectious_bronchitis_virus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 23/2292 23/10654 4.114981010913265e-16 3.0282622688046793e-15 1.385620241534621e-15 7321/6497/51592/64750/7323/8239/54778/7316/9611/9612/4089/60436/23327/7050/4088/142/5494/3065/6498/4087/6233/7311/7314 23 Avian_infectious_bronchitis_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 56/2292 93/10654 5.493883807435285e-16 3.977094147556412e-15 1.819770437359857e-15 54106/8454/1147/3665/3725/8945/5601/351/4790/6885/5606/5594/4214/6500/7099/4615/7316/7335/5970/4792/4793/3146/5519/5598/1432/4208/23291/5602/6195/57162/10454/6288/3654/7189/6285/5609/6233/51311/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/51284/7314/5595/5515/5516 56 Avian_infectious_bronchitis_virus R-HSA-72764 Eukaryotic Translation Termination 56/2292 93/10654 5.493883807435285e-16 3.977094147556412e-15 1.819770437359857e-15 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/6152/6136/6125/51065/6154/6141/6202/6232/2935/6160/6155/6175/6218/6209/6231/6229/11224/6205/6130/6142/6204/140801/6156/6143/6181/6124/6207/6233/7311/6223/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122 56 Avian_infectious_bronchitis_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 56/2292 93/10654 5.493883807435285e-16 3.977094147556412e-15 1.819770437359857e-15 54106/8454/1147/3665/3725/8945/5601/351/4790/6885/5606/5594/4214/6500/7099/4615/7316/7335/5970/4792/4793/3146/5519/5598/1432/4208/23291/5602/6195/57162/10454/6288/3654/7189/6285/5609/6233/51311/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/51284/7314/5595/5515/5516 56 Avian_infectious_bronchitis_virus R-HSA-391251 Protein folding 59/2292 101/10654 6.602367453187831e-16 4.7537045662952385e-15 2.1751184952465175e-15 2788/10694/26224/9134/8841/54331/59345/1459/2770/51807/8237/10575/10681/898/51764/1460/7277/94235/10381/10517/7203/10576/908/55970/6774/1457/2792/26272/346562/6468/2793/26270/6950/7846/2785/55294/2783/26190/2784/10238/2782/7157/2786/2771/10574/10564/10383/60/54461/84790/22948/26234/10693/2791/7280/84261/2773/2790/2787 59 Avian_infectious_bronchitis_virus R-HSA-3899300 SUMOylation of transcription cofactors 35/2292 45/10654 1.1341139430032164e-15 8.121719204732712e-15 3.716196791165039e-15 1912/1487/3622/8535/6045/51588/4869/80012/6613/10210/28996/1655/9612/1911/7341/1387/84733/10401/1616/2033/57332/7329/115426/10155/10499/6612/9063/25942/6294/648/11315/8648/10891/6015/8554 35 Avian_infectious_bronchitis_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 55/2292 92/10654 1.5678505846387034e-15 1.116779133015376e-14 5.1099661610234125e-15 54106/8454/1147/3725/8945/5601/351/4790/6885/5606/5594/4214/6500/7099/4615/7316/7335/5970/4792/4793/3146/5519/5598/1432/4208/23291/5602/6195/57162/10454/6288/3654/7189/6285/5609/6233/51311/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/51284/7314/5595/5515/5516 55 Avian_infectious_bronchitis_virus R-HSA-392170 ADP signalling through P2Y purinoceptor 12 22/2292 22/10654 1.9273338373581457e-15 1.3655365273197074e-14 6.248187524246172e-15 2788/54331/59345/64805/2770/10681/51764/94235/55970/2792/346562/2793/2785/2783/2784/2782/2786/2771/2791/2773/2790/2787 22 Avian_infectious_bronchitis_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 28/2292 32/10654 2.6003808560802445e-15 1.8230038422625712e-14 8.341387898451311e-15 57154/51377/10273/4738/9372/64750/7316/5501/56937/4092/4089/11171/23327/867/7046/4088/2280/9958/9040/4087/5499/6233/7514/7048/7311/9110/7040/7314 28 Avian_infectious_bronchitis_virus R-HSA-392518 Signal amplification 28/2292 32/10654 2.6003808560802445e-15 1.8230038422625712e-14 8.341387898451311e-15 2788/5321/54331/59345/64805/2770/10681/51764/94235/2769/55970/2792/346562/6714/1432/2793/2785/2783/2784/2782/2786/2771/9630/2791/2773/2790/2787/10672 28 Avian_infectious_bronchitis_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 57/2292 98/10654 2.692353055530874e-15 1.867819932274544e-14 8.546449666405572e-15 8454/1147/3725/8945/5601/351/4790/6885/5606/5594/4214/6500/10333/7099/4615/7316/7335/5970/4792/7096/4793/8651/3146/5519/5598/1432/4208/23291/5602/6195/57162/10454/6288/695/3654/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/7097/3551/57161/51231/7314/5595/5515/5516 57 Avian_infectious_bronchitis_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 57/2292 98/10654 2.692353055530874e-15 1.867819932274544e-14 8.546449666405572e-15 8454/1147/3725/8945/5601/351/4790/6885/5606/5594/4214/6500/10333/7099/4615/7316/7335/5970/4792/7096/4793/8651/3146/5519/5598/1432/4208/23291/5602/6195/57162/10454/6288/695/3654/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/7097/3551/57161/51231/7314/5595/5515/5516 57 Avian_infectious_bronchitis_virus R-HSA-2408557 Selenocysteine synthesis 55/2292 93/10654 3.0419406165922816e-15 2.0994118659590254e-14 9.606128262922996e-15 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/6152/6136/6125/51065/6154/6141/6202/6232/6160/6155/6175/6218/6209/6231/6229/11224/6205/6130/6142/6204/140801/6156/6143/6181/6124/6207/6233/7311/6223/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122 55 Avian_infectious_bronchitis_virus R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 33/2292 42/10654 4.4282297494559e-15 3.040413415605803e-14 1.3911801546038886e-14 2788/10694/54331/59345/1459/2770/10575/10681/51764/1460/94235/7203/10576/908/55970/1457/2792/346562/2793/6950/2785/2783/2784/2782/2786/2771/10574/22948/10693/2791/2773/2790/2787 33 Avian_infectious_bronchitis_virus R-HSA-1236975 Antigen processing-Cross presentation 57/2292 99/10654 5.030967724037434e-15 3.436537953034801e-14 1.5724320173914572e-14 1147/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10333/10197/7099/4615/9554/7316/10213/5709/5695/7096/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/695/5719/5704/6233/5716/7311/5694/7097/3551/5693/5721/5696/5691/7314 57 Avian_infectious_bronchitis_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 55/2292 94/10654 5.812512227711648e-15 3.950135860873426e-14 1.8074353275215058e-14 8454/1147/3665/3725/8945/5601/351/4790/6885/5606/7321/5594/6500/841/7098/7323/7316/7335/5970/4792/4793/3146/7322/5519/5598/1432/4208/23291/5602/6195/10454/6288/3654/7189/6285/5609/6233/10010/1385/2353/6196/7311/5518/1386/9641/6197/5599/5600/7334/3551/51231/7314/5595/5515/5516 55 Avian_infectious_bronchitis_virus R-HSA-168254 Influenza Infection 77/2292 155/10654 6.0530223469880165e-15 4.092703434613217e-14 1.8726689494555502e-14 6158/3303/6138/6144/3837/3838/6203/5903/9349/4736/6194/6191/7175/6128/51121/6132/9631/6147/6129/6217/5430/6230/6222/6152/6136/6125/51065/6154/6141/6202/6232/6160/6155/6175/6218/6209/4927/6231/6229/11224/6205/79902/6130/6142/3840/6204/3320/140801/6156/6143/6181/6124/6207/6233/7514/7311/6223/9972/1213/5610/1211/6188/6189/8021/7040/6396/6135/6201/3304/9045/6187/55746/6168/6208/6137/8480/6122 77 Avian_infectious_bronchitis_virus R-HSA-168255 Influenza Life Cycle 73/2292 144/10654 7.916794457934572e-15 5.325843544428712e-14 2.436908022936798e-14 6158/3303/6138/6144/3837/6203/5903/9349/4736/6194/6191/7175/6128/51121/6132/9631/6147/6129/6217/5430/6230/6222/6152/6136/6125/51065/6154/6141/6202/6232/6160/6155/6175/6218/6209/4927/6231/6229/11224/6205/79902/6130/6142/6204/3320/140801/6156/6143/6181/6124/6207/6233/7514/7311/6223/9972/1213/1211/6188/6189/8021/6396/6135/6201/3304/9045/6187/55746/6168/6208/6137/8480/6122 73 Avian_infectious_bronchitis_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 30/2292 37/10654 1.6892031018954704e-14 1.1306625787561641e-13 5.173491647698902e-14 1017/1029/207/11200/472/117584/639/7316/890/80196/983/4194/5519/1616/10000/900/7157/8900/208/6233/5527/2475/7311/5518/7874/51230/7314/4193/5515/5516 30 Avian_infectious_bronchitis_virus R-HSA-927802 Nonsense-Mediated Decay (NMD) 62/2292 115/10654 2.1571241283745468e-14 1.4294971835795504e-13 6.540847710546544e-14 6158/9887/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/6152/6136/6125/51065/6154/6141/26986/6202/6232/2935/6160/6155/6175/6218/6209/6231/6229/11224/6205/6130/6142/6204/1981/140801/6156/6143/6181/6124/6207/6233/23381/7311/6223/5518/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/5515 62 Avian_infectious_bronchitis_virus R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 62/2292 115/10654 2.1571241283745468e-14 1.4294971835795504e-13 6.540847710546544e-14 6158/9887/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/6152/6136/6125/51065/6154/6141/26986/6202/6232/2935/6160/6155/6175/6218/6209/6231/6229/11224/6205/6130/6142/6204/1981/140801/6156/6143/6181/6124/6207/6233/23381/7311/6223/5518/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/5515 62 Avian_infectious_bronchitis_virus R-HSA-166166 MyD88-independent TLR4 cascade 56/2292 99/10654 2.5065395170843243e-14 1.6446850427371035e-13 7.525467360082053e-14 8454/1147/3665/3725/8945/5601/351/4790/6885/5606/7321/5594/6500/841/7099/7323/7316/7335/5970/4792/4793/3146/7322/5519/5598/1432/4208/23291/5602/6195/10454/6288/3654/7189/6285/5609/6233/10010/1385/2353/6196/7311/5518/1386/9641/6197/5599/5600/7334/3551/5781/51231/7314/5595/5515/5516 56 Avian_infectious_bronchitis_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 56/2292 99/10654 2.5065395170843243e-14 1.6446850427371035e-13 7.525467360082053e-14 8454/1147/3665/3725/8945/5601/351/4790/6885/5606/7321/5594/6500/841/7099/7323/7316/7335/5970/4792/4793/3146/7322/5519/5598/1432/4208/23291/5602/6195/10454/6288/3654/7189/6285/5609/6233/10010/1385/2353/6196/7311/5518/1386/9641/6197/5599/5600/7334/3551/5781/51231/7314/5595/5515/5516 56 Avian_infectious_bronchitis_virus R-HSA-114452 Activation of BH3-only proteins 26/2292 30/10654 4.370096600079101e-14 2.839496912831884e-13 1.299248231807856e-13 23368/27113/596/10018/7531/7027/7532/207/10971/7533/2810/7534/1869/8655/5366/10000/5534/7157/8626/208/7161/5599/7159/637/140735/7529 26 Avian_infectious_bronchitis_virus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 26/2292 30/10654 4.370096600079101e-14 2.839496912831884e-13 1.299248231807856e-13 11065/7319/7321/65264/7320/10477/92912/7326/8239/7316/7317/54926/55236/3093/7322/7328/7324/6233/7327/7311/55284/27338/7874/7332/997/7314 26 Avian_infectious_bronchitis_virus R-HSA-5696398 Nucleotide Excision Repair 60/2292 111/10654 4.8575109335300705e-14 3.1408760016806085e-13 1.4371480993939252e-13 10450/9318/6118/902/2074/5430/7515/5982/6613/7336/86/8450/54778/7316/9978/4331/64708/5111/1643/10980/6119/7341/10401/1161/1642/2965/5985/10920/2033/142/2068/10987/2071/5984/7329/6233/2067/51426/2873/2968/7311/6612/60/8533/5983/6117/7334/5981/10714/7874/1022/8178/5886/50813/7508/7314/51138/8451/8554/7528 60 Avian_infectious_bronchitis_virus R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 27/2292 32/10654 5.434913082760434e-14 3.4972484184719315e-13 1.6002108695236673e-13 2788/2149/54331/59345/5594/10681/409/51764/94235/2769/55970/2792/6714/2793/408/2785/2783/2784/2768/2782/2786/9630/2791/5595/2790/2787/10672 27 Avian_infectious_bronchitis_virus R-HSA-5685942 HDR through Homologous Recombination (HRR) 43/2292 67/10654 5.5147752620992136e-14 3.5153454159530286e-013 1.6084913828329412e-13 6118/80010/83990/5888/9156/5883/1763/7486/10111/675/5982/545/472/580/11073/7316/116028/641/5111/6119/3364/10524/4683/144715/5985/84126/1111/5984/79728/6233/51426/672/5932/7311/7156/5983/6117/5981/10714/5884/5810/83695/7314 43 Avian_infectious_bronchitis_virus R-HSA-69473 G2/M DNA damage checkpoint 54/2292 95/10654 5.515819759265638e-14 3.5153454159530286e-013 1.6084913828329412e-13 6118/80010/83990/9156/5883/1763/7531/7486/10111/7532/10971/51588/51720/5982/7533/2810/11200/545/472/7336/7534/580/11073/891/116028/983/641/9656/6119/3364/7341/10524/4683/144715/5985/995/84126/1111/7157/5984/8924/672/5932/7158/79184/7156/5983/6117/7334/7465/5884/5810/83695/7529 54 Avian_infectious_bronchitis_virus R-HSA-6804757 Regulation of TP53 Degradation 29/2292 36/10654 6.44009663507272e-14 4.084861294246125e-13 1.8690806775474214e-13 1017/1029/207/11200/472/117584/7316/890/80196/983/4194/5519/1616/10000/900/7157/8900/208/6233/5527/2475/7311/5518/7874/51230/7314/4193/5515/5516 29 Avian_infectious_bronchitis_virus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 23/2292 25/10654 7.812074997979692e-14 4.93160374280045e-13 2.256518545188447e-13 11065/246184/7321/991/8697/8881/7316/51433/119504/51529/7324/64682/29945/10393/6233/51434/701/7311/9184/25906/29882/7314/996 23 Avian_infectious_bronchitis_virus R-HSA-983231 Factors involved in megakaryocyte development and platelet production 79/2292 168/10654 1.217022905269391e-13 7.646577876503909e-13 3.498789782278935e-13 55582/3831/1017/25/113220/9371/64837/85440/5868/3797/23348/23186/11127/51807/9585/23095/2625/347688/29127/3798/830/3832/7277/10381/81928/55605/91768/23303/832/285643/3659/3796/26153/3043/124602/10112/1062/64147/3705/3717/7846/55614/146909/89953/56992/547/90990/4602/3066/3065/998/7157/7975/23028/3834/11004/3835/23046/55083/147700/10749/3833/3799/2626/10383/24137/60/25942/84790/84643/9493/7465/3456/1020/22920/81930/7280/221458/829 79 Avian_infectious_bronchitis_virus R-HSA-5696395 Formation of Incision Complex in GG-NER 32/2292 43/10654 1.6951201214517024e-13 1.0600469491895152e-12 4.850380777467436e-13 6118/902/6613/7336/8450/54778/7316/9978/4331/1643/6119/7341/10401/1642/2965/142/2068/2071/7329/6233/2067/2968/7311/6612/6117/7334/1022/5886/7508/7314/8451/8554 32 Avian_infectious_bronchitis_virus R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 19/2292 19/10654 1.976159585589404e-13 1.224299799072133e-12 5.601940759149401e-13 11065/246184/7321/991/8697/8881/51433/119504/51529/8556/7324/64682/29945/10393/51434/51343/25906/29882/996 19 Avian_infectious_bronchitis_virus R-HSA-176412 Phosphorylation of the APC/C 19/2292 19/10654 1.976159585589404e-13 1.224299799072133e-12 5.601940759149401e-13 11065/246184/7321/8697/8881/891/983/51433/119504/51529/7324/64682/29945/10393/51434/25906/5347/29882/996 19 Avian_infectious_bronchitis_virus R-HSA-2559585 Oncogene Induced Senescence 27/2292 33/10654 2.3756221365608347e-13 1.4599784031650203e-12 6.680318440276172e-13 1019/1029/7027/57690/5594/27327/5925/192670/7316/2114/1869/6667/4194/1031/1021/192669/7157/23112/6233/1030/7311/4343/26523/2113/7314/5595/4193 27 Avian_infectious_bronchitis_virus R-HSA-168273 Influenza Viral RNA Transcription and Replication 67/2292 134/10654 2.3784933444955663e-13 1.4599784031650203e-12 6.680318440276172e-13 6158/6138/6144/6203/5903/9349/4736/6194/6191/7175/6128/51121/6132/9631/6147/6129/6217/5430/6230/6222/6152/6136/6125/51065/6154/6141/6202/6232/6160/6155/6175/6218/6209/4927/6231/6229/11224/6205/79902/6130/6142/6204/3320/140801/6156/6143/6181/6124/6207/6233/7311/6223/9972/6188/6189/8021/6396/6135/6201/9045/6187/55746/6168/6208/6137/8480/6122 67 Avian_infectious_bronchitis_virus R-HSA-201681 TCF dependent signaling in response to WNT 99/2292 233/10654 2.87466756818464e-13 1.756448257257771e-12 8.036854282853244e-13 5718/27123/9070/5689/51176/8945/5684/8295/857/5720/6662/7015/1487/6597/5682/1499/864/1459/5700/122706/5707/1856/207/1454/1452/5690/5717/5929/9491/23198/79577/6736/1460/143471/5706/5705/10197/6657/7534/64750/8452/7316/10213/5709/9978/5695/1457/5714/4609/9861/5715/5519/5711/2932/5701/10524/5688/1387/5687/1455/5685/5683/5698/5708/5692/5686/5713/2033/54894/5699/8312/5710/5702/3065/5719/208/57680/5704/6233/5527/1855/5716/1857/7514/23072/7311/5518/331/6659/5694/5693/5721/5696/6259/5691/7314/4221/5515/5516 99 Avian_infectious_bronchitis_virus R-HSA-5693607 Processing of DNA double-strand break ends 54/2292 98/10654 3.156851834721697e-13 1.92005782824169e-12 8.785470859427363e-13 1017/6118/80010/83990/9156/5883/1763/7486/10111/51588/51720/5982/63967/5531/51548/545/472/6613/7336/580/11073/7316/116028/890/641/9656/6119/3364/7341/10524/4683/144715/5985/84126/1111/8900/5984/7329/8924/6233/672/5932/7158/7311/6047/79184/7156/5983/6117/7334/5884/5810/83695/7314 54 Avian_infectious_bronchitis_virus R-HSA-418597 G alpha (z) signalling events 34/2292 48/10654 3.2061466703191967e-13 1.9411760749387137e-12 8.882100105812512e-13 2788/151/54331/59345/2770/10681/51764/112/94235/114/108/150/113/55970/111/107/2792/346562/152/2793/2785/2783/2784/2782/2786/2771/5580/196883/115/2791/109/2773/2790/2787 34 Avian_infectious_bronchitis_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 23/2292 26/10654 5.3866413192044e-13 3.2466091570951404e-12 1.4855276607855907e-12 57154/51377/10273/9372/64750/7316/5501/56937/4092/11171/23327/7046/4088/9958/4087/5499/6233/7514/7048/7311/9110/7040/7314 23 Avian_infectious_bronchitis_virus R-HSA-111885 Opioid Signalling 51/2292 91/10654 5.906959241556673e-13 3.5441755449340036e-12 1.6216829781229559e-12 2788/818/3838/5321/54331/59345/2770/5594/10681/51764/112/94235/114/3708/108/113/5173/5530/55970/111/107/5443/3709/2792/346562/5519/4988/2793/5136/2785/5534/2783/2784/2782/2786/5499/2771/5580/1385/5518/3710/196883/115/1020/2791/109/2773/2790/5515/2787/5516 51 Avian_infectious_bronchitis_virus R-HSA-76002 Platelet activation, signaling and aggregation 107/2292 262/10654 6.892919873240272e-13 4.117205951191051e-12 1.8838803901846204e-12 5295/2788/151/2149/5777/5590/351/6464/5321/5290/54331/7018/7042/5340/5747/59345/64805/7424/2770/5336/2316/207/7094/3959/7422/5594/10681/409/5908/3082/7414/51764/7277/94235/3708/7534/5196/2769/3827/150/1950/55970/308/6850/3709/2792/346562/6714/152/22927/1191/1432/27154/6403/2793/4067/81/3309/7078/2335/2534/408/2785/2783/2784/2768/1445/2782/8525/998/5894/3481/2786/2771/10487/6654/2885/1398/5473/7410/5580/7409/8407/3932/7076/3479/387/3710/5296/7040/10916/213/5660/9630/350/5781/7057/1278/2791/7043/2773/5595/2790/5054/2787/3700/10672 107 Avian_infectious_bronchitis_virus R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 20/2292 21/10654 7.064798349909305e-13 4.2010318759282116e-12 1.9222360171980674e-12 7832/4849/4869/4850/9337/10769/25904/246175/4848/23019/28984/995/7157/55571/55835/5325/57472/85456/29883/1263 20 Avian_infectious_bronchitis_virus R-HSA-202040 G-protein activation 24/2292 28/10654 7.193254747062298e-13 4.25840681026088e-12 1.948488654291963e-12 2788/54331/59345/2770/10681/51764/94235/5173/55970/5443/2792/346562/4988/2793/2785/2783/2784/2782/2786/2771/2791/2773/2790/2787 24 Avian_infectious_bronchitis_virus R-HSA-948021 Transport to the Golgi and subsequent modification 83/2292 185/10654 7.322356949504832e-13 4.315654626876299e-12 1.974683127043921e-12 2348/84364/6811/23256/22820/6711/11014/11258/6712/1783/4253/51014/51807/286/2801/93661/347688/5861/55860/830/7277/10381/10671/1780/1604/9554/377/1781/9570/22872/966/8655/1315/11196/84516/1639/832/57731/81562/10282/10121/55738/8615/6710/81876/11316/11015/7846/8729/23423/10972/51226/51143/1314/3630/10540/381/6708/9276/287/6709/51332/9871/10383/84790/378/10945/6396/375/26286/1453/288/26958/140735/7280/10959/10652/54732/829/51164/1778/22818/372 83 Avian_infectious_bronchitis_virus R-HSA-6804758 Regulation of TP53 Activity through Acetylation 25/2292 30/10654 8.482437081482625e-13 4.977359556182757e-12 2.2774547044648463e-12 23774/64769/7862/3622/9219/207/5931/84289/1108/29117/5928/27154/57459/10000/54815/2033/7994/3066/3065/7157/1107/5371/208/5300/53615 25 Avian_infectious_bronchitis_virus R-HSA-3371556 Cellular response to heat stress 50/2292 89/10654 8.787249863311318e-13 5.133603867513454e-12 2.348946293101225e-12 818/3303/6118/5903/573/7175/9631/7531/1915/5594/3308/10049/1410/10013/545/472/3337/3313/10808/3305/9532/4927/7415/79902/6119/2932/1387/57805/3310/3309/3320/2033/7266/9531/3326/2475/3306/9972/23411/8021/9529/6117/6396/3304/3312/55746/2288/8480/10728/5595 50 Avian_infectious_bronchitis_virus R-HSA-8964315 G beta:gamma signalling through BTK 18/2292 18/10654 9.242934631631043e-13 5.3762397071321176e-012 2.459967433562112e-12 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/695/2786/2791/2790/2787 18 Avian_infectious_bronchitis_virus R-HSA-450294 MAP kinase activation 40/2292 64/10654 1.4975967951460062e-12 8.67303883101948e-12 3.968460157389189e-12 8454/1147/3725/8945/5601/4790/6885/5606/5594/6500/7316/7335/5519/5598/1432/4208/23291/5602/6195/10454/3654/7189/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595/5515/5516 40 Avian_infectious_bronchitis_virus R-HSA-418592 ADP signalling through P2Y purinoceptor 1 22/2292 25/10654 2.2345593432163852e-12 1.2884991537507467e-11 5.8956931406802785e-12 2788/5321/54331/59345/10681/51764/94235/2769/55970/2792/6714/1432/2793/2785/2783/2784/2782/2786/9630/2791/2790/2787 22 Avian_infectious_bronchitis_virus R-HSA-3247509 Chromatin modifying enzymes 109/2292 274/10654 3.111913205034907e-12 1.7702858900979644e-11 8.100170146726106e-12 55904/23774/9070/10196/1019/8295/8841/8464/29943/23326/55167/11091/4790/54859/9869/64769/84148/79595/7862/6597/2648/23186/10474/8242/2146/5978/1788/9112/9219/51147/6839/6871/5929/23569/5931/284058/6598/117143/79813/6599/86/7403/8819/54496/9611/2874/84289/5970/11143/9612/29072/63976/6603/1108/2122/27097/84444/8850/5928/10524/1387/27154/56950/57459/3717/8289/54815/2033/23512/6602/595/7994/3066/3065/1107/79084/23028/23135/55693/23587/10498/9757/22992/57504/26610/80854/6881/58508/10499/57634/1386/6880/10419/60/9739/8726/10902/6883/3276/6601/51230/10284/6187/53615/9913/8648/64754/4297/10919 109 Avian_infectious_bronchitis_virus R-HSA-4839726 Chromatin organization 109/2292 274/10654 3.111913205034907e-12 1.7702858900979644e-11 8.100170146726106e-12 55904/23774/9070/10196/1019/8295/8841/8464/29943/23326/55167/11091/4790/54859/9869/64769/84148/79595/7862/6597/2648/23186/10474/8242/2146/5978/1788/9112/9219/51147/6839/6871/5929/23569/5931/284058/6598/117143/79813/6599/86/7403/8819/54496/9611/2874/84289/5970/11143/9612/29072/63976/6603/1108/2122/27097/84444/8850/5928/10524/1387/27154/56950/57459/3717/8289/54815/2033/23512/6602/595/7994/3066/3065/1107/79084/23028/23135/55693/23587/10498/9757/22992/57504/26610/80854/6881/58508/10499/57634/1386/6880/10419/60/9739/8726/10902/6883/3276/6601/51230/10284/6187/53615/9913/8648/64754/4297/10919 109 Avian_infectious_bronchitis_virus R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 19/2292 20/10654 3.1498330026517838e-12 1.7702858900979644e-11 8.100170146726106e-12 11065/246184/7321/991/8697/8881/51433/119504/51529/7324/64682/29945/10393/51434/701/9184/25906/29882/996 19 Avian_infectious_bronchitis_virus R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 19/2292 20/10654 3.1498330026517838e-12 1.7702858900979644e-11 8.100170146726106e-12 11065/246184/7321/991/8697/8881/51433/119504/51529/7324/64682/29945/10393/51434/701/9184/25906/29882/996 19 Avian_infectious_bronchitis_virus R-HSA-3232118 SUMOylation of transcription factors 19/2292 20/10654 3.1498330026517838e-12 1.7702858900979644e-11 8.100170146726106e-12 7020/6670/7021/1029/9112/51588/3090/6613/7341/10401/7022/7157/668/7329/7158/6612/9063/4193/8554 19 Avian_infectious_bronchitis_virus R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 19/2292 20/10654 3.1498330026517838e-12 1.7702858900979644e-11 8.100170146726106e-12 23368/27113/55240/472/5366/84883/147923/1387/51499/94241/7157/8626/63970/7161/581/7159/637/665/27166 19 Avian_infectious_bronchitis_virus R-HSA-450604 KSRP (KHSRP) binds and destabilizes mRNA 17/2292 17/10654 4.3216305791938125e-12 2.4085405571071793e-11 1.1020586238067464e-11 5393/23404/5073/207/7534/1432/51013/11340/51010/5600/56915/8570/23016/54512/118460/167227/22894 17 Avian_infectious_bronchitis_virus R-HSA-8934593 Regulation of RUNX1 Expression and Activity 17/2292 17/10654 4.3216305791938125e-12 2.4085405571071793e-11 1.1020586238067464e-11 27161/894/57690/27327/192670/865/6714/1021/595/192669/861/896/5371/23112/4343/26523/5781 17 Avian_infectious_bronchitis_virus R-HSA-9006931 Signaling by Nuclear Receptors 116/2292 299/10654 4.397811343456405e-12 2.440785295618305e-11 1.1168126174830082e-11 5295/2788/3727/27161/3725/3838/596/5590/4893/6464/8841/857/112724/5290/54331/5241/2309/4435/5747/59345/5160/5430/2770/207/10901/1903/2625/57690/5594/2069/1027/3315/10681/27327/51523/51764/94235/4318/5481/6720/192670/200845/348/4313/1950/9611/865/55970/5469/2874/1655/2194/4314/9612/6667/2792/346562/6714/2099/4609/7391/8850/10524/1387/2793/10000/3320/2033/2785/4846/595/2783/4602/2784/8312/2782/192669/3065/2066/861/23028/2786/23112/2771/208/10498/3326/7514/1385/1025/2353/10499/1386/6908/1956/5296/4343/3845/904/1071/3276/3265/26523/29116/8202/8648/3480/2791/2288/2773/10728/5595/2790/2787/7528/6387 116 Avian_infectious_bronchitis_virus R-HSA-5693532 DNA Double-Strand Break Repair 75/2292 166/10654 6.165525294025154e-12 3.407667921842948e-11 1.5592221643330704e-11 8467/1017/6118/80010/25/3838/83990/5888/9156/5883/1763/7486/10111/51588/7520/51720/675/7515/5982/63967/5531/51548/11200/545/472/6613/7336/51567/580/11073/5591/7316/116028/890/641/5111/64421/9656/6119/3364/7341/10524/4683/144715/5985/84126/142/1111/7157/8900/5984/7329/79728/8924/6233/2067/51426/672/5932/7158/7311/6047/79184/7156/5983/6117/5599/7334/5981/10714/2547/5884/5810/83695/7314 75 Avian_infectious_bronchitis_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 32/2292 47/10654 8.808949675412665e-12 4.8485623833263097e-11 2.218521906073916e-11 8454/8841/2648/9734/892/23462/51564/6500/3091/10013/7316/9978/9611/9759/9612/1024/4609/10014/22938/8850/1387/26508/2033/55294/3066/3065/9794/6233/7311/3516/4851/7314 32 Avian_infectious_bronchitis_virus R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 23/2292 28/10654 1.2892457250454095e-11 7.066976566915578e-11 3.23358576911974e-11 2788/54331/59345/2770/10681/51764/112/94235/150/55970/111/2792/152/2793/2785/2783/2784/2782/2786/2771/2791/2790/2787 23 Avian_infectious_bronchitis_virus R-HSA-6804760 Regulation of TP53 Activity through Methylation 18/2292 19/10654 1.4004488546038008e-11 7.645073255460092e-11 3.498101323622091e-11 133383/11200/472/79813/7316/4194/56950/2033/7157/91875/6233/7311/10419/133746/26013/10919/7314/4193 18 Avian_infectious_bronchitis_virus R-HSA-2132295 MHC class II antigen presentation 60/2292 123/10654 1.6133414153277033e-11 8.771309245781636e-11 4.0134250460783686e-11 3831/9371/64837/11258/6712/3797/1783/11127/51807/93661/347688/29127/3798/55860/830/3832/7277/10381/10671/1780/1781/22872/8655/84516/1639/832/285643/10121/3796/26153/10112/1062/7846/89953/56992/51143/10540/11004/3835/9871/147700/1759/3799/1213/10383/24137/1211/84790/84643/9493/6396/375/22920/81930/7879/140735/7280/829/51164/1778 60 Avian_infectious_bronchitis_virus R-HSA-5693538 Homology Directed Repair 65/2292 138/10654 1.668717889447892e-11 9.032385013610067e-11 4.132883612201857e-11 1017/6118/80010/25/83990/5888/9156/5883/1763/7486/10111/51588/51720/675/7515/5982/63967/5531/51548/545/472/6613/7336/580/11073/7316/116028/890/641/5111/9656/6119/3364/7341/10524/4683/144715/5985/84126/142/1111/8900/5984/7329/79728/8924/6233/2067/51426/672/5932/7158/7311/6047/79184/7156/5983/6117/7334/5981/10714/5884/5810/83695/7314 65 Avian_infectious_bronchitis_virus R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 63/2292 132/10654 1.6749242480192843e-11 9.032385013610067e-11 4.132883612201857e-11 1017/6118/80010/25/83990/5888/9156/5883/1763/7486/10111/51588/51720/675/5982/63967/5531/51548/545/472/6613/7336/580/11073/7316/116028/890/641/5111/9656/6119/3364/7341/10524/4683/144715/5985/84126/1111/8900/5984/7329/79728/8924/6233/2067/51426/672/5932/7158/7311/6047/79184/7156/5983/6117/7334/5981/10714/5884/5810/83695/7314 63 Avian_infectious_bronchitis_virus R-HSA-382556 ABC-family proteins mediated transport 53/2292 103/10654 1.843369252222372e-11 9.900676790162095e-11 4.530181651259565e-11 5718/5689/5684/5720/5682/5700/122706/5707/79139/5243/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/8894/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 53 Avian_infectious_bronchitis_virus R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 56/2292 112/10654 2.2034651397061603e-11 1.178721110878958e-10 5.3933896254063286e-11 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/6152/6136/6125/51065/6154/6141/6202/6232/6160/6155/6175/6218/6209/6231/6229/11224/6205/6130/6142/6204/140801/6156/6143/6181/6124/6207/6233/7311/6223/6730/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122 56 Avian_infectious_bronchitis_virus R-HSA-977444 GABA B receptor activation 28/2292 39/10654 2.4245880104835113e-11 1.2866737967984212e-10 5.887340985824924e-11 2788/54331/2770/2550/112/94235/114/108/113/55970/111/107/9568/2792/346562/2793/2785/2783/2784/2782/2786/2771/196883/115/109/2773/2790/2787 28 Avian_infectious_bronchitis_virus R-HSA-991365 Activation of GABAB receptors 28/2292 39/10654 2.4245880104835113e-11 1.2866737967984212e-10 5.887340985824924e-11 2788/54331/2770/2550/112/94235/114/108/113/55970/111/107/9568/2792/346562/2793/2785/2783/2784/2782/2786/2771/196883/115/109/2773/2790/2787 28 Avian_infectious_bronchitis_virus R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs 62/2292 130/10654 2.5224069763440412e-11 1.3332722589247074e-10 6.100558225994987e-11 5718/5689/25/5684/5720/902/5682/6929/5700/122706/5707/5690/2625/5717/9491/23198/143471/6938/5706/5705/10197/7316/10213/5709/865/5695/4331/10413/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/4602/5710/5702/83737/861/5719/5704/6233/5716/7311/7161/5694/1022/5693/5721/4297/5696/5691/7314 62 Avian_infectious_bronchitis_virus R-HSA-72649 Translation initiation complex formation 36/2292 58/10654 2.6499685438770778e-11 1.389668543481995e-10 6.358606659365222e-11 6203/6194/6191/8666/6217/6230/6222/8668/8667/51065/8662/10480/26986/6202/6232/8661/6218/6209/6231/6229/6205/6204/8894/1981/6207/6233/1975/6223/3646/51386/6188/6189/8665/6201/6187/6208 36 Avian_infectious_bronchitis_virus R-HSA-72702 Ribosomal scanning and start codon recognition 36/2292 58/10654 2.6499685438770778e-11 1.389668543481995e-10 6.358606659365222e-11 6203/6194/6191/8666/6217/6230/6222/1983/8668/8667/51065/8662/10480/6202/6232/8661/6218/6209/6231/6229/6205/6204/8894/1981/6207/6233/1975/6223/3646/51386/6188/6189/8665/6201/6187/6208 36 Avian_infectious_bronchitis_virus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 44/2292 79/10654 3.0551549380378717e-11 1.5958691676339e-10 7.302104062431076e-11 10450/9318/6118/902/2074/5430/7515/5982/8450/7316/9978/4331/64708/5111/10980/6119/1161/1642/2965/5985/10920/2033/2068/10987/2071/5984/6233/2067/51426/2873/2968/7311/8533/5983/6117/5981/10714/7874/1022/8178/50813/7314/51138/8451 44 Avian_infectious_bronchitis_virus R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 33/2292 51/10654 3.474759698217274e-11 1.8079609054786753e-10 8.272557011791948e-11 6203/6194/6191/8666/6217/6230/6222/8668/8667/51065/8662/10480/6202/6232/8661/6218/6209/6231/6229/6205/6204/8894/6207/6233/6223/3646/51386/6188/6189/8665/6201/6187/6208 33 Avian_infectious_bronchitis_virus R-HSA-428930 Thromboxane signalling through TP receptor 20/2292 23/10654 3.781439735237217e-11 1.9598746020762543e-10 8.967657615000404e-11 2788/54331/59345/10681/51764/94235/2769/55970/2792/2793/2785/2783/2784/2782/2786/9630/2791/2790/2787/10672 20 Avian_infectious_bronchitis_virus R-HSA-392451 G beta:gamma signalling through PI3Kgamma 21/2292 25/10654 4.5889859257243314e-11 2.369197384908841e-10 1.0840566507525042e-10 2788/54331/59345/207/10681/51764/94235/55970/2792/2793/10000/2785/2783/2784/2782/2786/208/387/2791/2790/2787 21 Avian_infectious_bronchitis_virus R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 36/2292 59/10654 5.396488887740932e-11 2.775337142266765e-10 1.269891105873603e-10 6203/6194/6191/8666/6217/6230/6222/8668/8667/51065/8662/10480/26986/6202/6232/8661/6218/6209/6231/6229/6205/6204/8894/1981/6207/6233/1975/6223/3646/51386/6188/6189/8665/6201/6187/6208 36 Avian_infectious_bronchitis_virus R-HSA-448424 Interleukin-17 signaling 41/2292 72/10654 5.573838843966768e-11 2.85552051544759e-10 1.3065800367031412e-10 8454/3605/1147/3725/8945/5601/4790/6885/5606/5594/6500/7316/7335/5519/5598/1432/4208/23291/5602/6195/10454/3654/7189/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595/5515/5516 41 Avian_infectious_bronchitis_virus R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 17/2292 18/10654 6.207636155171581e-11 3.168035003328945e-10 1.4495750489390386e-10 7027/25946/2810/5934/891/983/6790/5933/5111/1647/2033/995/1874/7157/10498/581/3276 17 Avian_infectious_bronchitis_virus R-HSA-2408522 Selenoamino acid metabolism 57/2292 118/10654 8.485840013216336e-11 4.314175151757313e-10 1.9740061742275048e-10 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/6152/6136/6125/51065/6154/6141/6202/6232/6160/6155/6175/6218/6209/6231/6229/11224/6205/6130/6142/6204/7965/140801/6156/6143/6181/6124/6207/6233/7311/6223/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/7296 57 Avian_infectious_bronchitis_virus R-HSA-8964616 G beta:gamma signalling through CDC42 18/2292 20/10654 1.1169638843651394e-10 5.657018608267551e-10 2.588441421042289e-10 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/998/2786/2791/2790/2787 18 Avian_infectious_bronchitis_virus R-HSA-73893 DNA Damage Bypass 31/2292 48/10654 1.479333266090488e-10 7.440464440985272e-10 3.4044799362497814e-10 6118/7320/5982/7706/8450/7316/9978/11201/5111/9100/7415/6119/51455/1642/5985/25898/7398/5984/9246/57599/6233/51426/7311/7318/5983/6117/5981/10714/7314/51514/8451 31 Avian_infectious_bronchitis_virus R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 24/2292 32/10654 1.480272580226049e-10 7.440464440985272e-10 3.4044799362497814e-10 5295/5777/4690/5336/640/930/3708/6850/3709/4067/29760/2534/695/974/6654/30011/2885/7409/5293/3710/118788/27071/973/933 24 Avian_infectious_bronchitis_virus R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 78/2292 185/10654 1.5349056653285784e-10 7.686068970743107e-10 3.516859438960218e-10 6158/5393/6138/6144/2091/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/23404/6217/6230/6222/1454/6152/6136/27043/6125/51065/6154/6141/6202/6232/6160/55272/55781/6155/6175/6218/6209/10200/6231/6229/11224/6205/6130/6142/6204/23481/140801/6156/6143/51013/6181/6124/6207/10969/6233/7311/6223/26168/11340/6188/6189/51010/26354/6135/6201/56915/1453/9045/6187/4691/23016/6168/6208/54512/6137/10813/118460/6122/22894 78 Avian_infectious_bronchitis_virus R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 27/2292 39/10654 2.1167341487915263e-10 1.0559887214195928e-9 4.831811835798517e-10 10694/26224/9134/8841/8237/10575/898/10517/7203/10576/908/6774/26272/6468/26270/6950/55294/26190/10238/7157/10574/10564/54461/22948/26234/10693/84261 27 Avian_infectious_bronchitis_virus R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 16/2292 17/10654 2.7424125859093273e-10 1.3630199867280688e-9 6.236672769998038e-10 2308/857/2290/2309/57060/2660/4303/1027/5934/1026/901/4089/1647/9314/4088/4087 16 Avian_infectious_bronchitis_virus R-HSA-5628897 TP53 Regulates Metabolic Genes 45/2292 86/10654 2.9917838210642827e-10 1.4814334757091541e-9 6.778488876526001e-10 27161/5563/27165/83667/7531/7532/207/10971/9997/57690/51422/7249/27327/7295/7533/2810/53632/27244/192670/7534/2539/54205/143686/5571/10000/2877/10128/5728/54541/192669/7157/8626/23112/208/10542/2475/5562/4343/50484/26523/5564/5052/5565/7529/7296 45 Avian_infectious_bronchitis_virus R-HSA-4086398 Ca2+ pathway 36/2292 62/10654 3.9283924351359243e-10 1.938006934667056e-9 8.867599298026123e-10 2788/27161/51176/54331/6885/1499/59345/51701/4772/57690/10681/27327/51764/94235/3708/192670/5530/55970/3709/2792/2793/2785/5534/2783/2784/2782/192669/2786/23112/3710/4343/3845/26523/2791/2790/2787 36 Avian_infectious_bronchitis_virus R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 14/2292 14/10654 4.408197608395651e-10 2.1587202994055176e-9 9.877501607047532e-10 1017/9134/1820/57060/25946/1027/898/1869/890/1026/7157/8900/144455/79733 14 Avian_infectious_bronchitis_virus R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 14/2292 14/10654 4.408197608395651e-10 2.1587202994055176e-9 9.877501607047532e-10 23368/25946/5457/207/54971/10848/5458/10000/7157/8626/208/7161/7159/51230 14 Avian_infectious_bronchitis_virus R-HSA-6783783 Interleukin-10 signaling 30/2292 47/10654 4.5039337087602165e-10 2.197523699658831e-9 1.005505154182443e-9 729230/3557/7124/1437/6351/3553/1230/2919/5743/941/3383/3576/2357/2920/6352/6774/6348/1440/3627/3606/6364/3552/942/6363/6347/7076/7297/3569/1234/3586 30 Avian_infectious_bronchitis_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 17/2292 19/10654 4.70687282099977e-10 2.2715777527433675e-9 1.0393895359873637e-9 5295/4893/6464/5290/5335/7316/1950/867/3320/6654/6233/2885/7311/1956/3845/3265/7314 17 Avian_infectious_bronchitis_virus R-HSA-392851 Prostacyclin signalling through prostacyclin receptor 17/2292 19/10654 4.70687282099977e-10 2.2715777527433675e-9 1.0393895359873637e-9 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Avian_infectious_bronchitis_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 17/2292 19/10654 4.70687282099977e-10 2.2715777527433675e-9 1.0393895359873637e-9 5295/4893/6464/5290/5335/7316/1950/867/3320/6654/6233/2885/7311/1956/3845/3265/7314 17 Avian_infectious_bronchitis_virus R-HSA-186763 Downstream signal transduction 22/2292 29/10654 6.092619070528471e-10 2.929735957380478e-9 1.340538264045596e-9 5295/4893/5290/5335/4690/5921/6778/6776/6774/6772/6714/5159/6654/2885/1398/5296/3845/6777/3265/1399/5781/5156 22 Avian_infectious_bronchitis_virus R-HSA-1227986 Signaling by ERBB2 31/2292 50/10654 6.689997730651369e-10 3.205423373103462e-9 1.4666825770719966e-9 5295/4893/8065/6464/5290/5335/26469/5782/10273/207/10193/2069/2064/7316/1950/6714/10000/3320/2534/2066/208/6654/6233/2885/5580/7311/387/1956/3845/3265/7314 31 Avian_infectious_bronchitis_virus R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress 21/2292 27/10654 6.813334737112757e-10 3.252817874492542e-9 1.488368539063681e-9 5393/4802/23404/5073/1051/3576/468/4800/4801/51013/6347/11340/467/51010/56915/8570/23016/54512/118460/167227/22894 21 Avian_infectious_bronchitis_virus R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 26/2292 38/10654 6.898178659039953e-10 3.2815621335147204e-9 1.5015208434526815e-9 1912/6597/1459/8535/6045/80012/1460/6598/6599/86/865/28996/1457/1911/6603/84733/8289/2033/6602/57332/861/648/6601/23466/23429/6015 26 Avian_infectious_bronchitis_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 30/2292 48/10654 9.544934446543144e-10 4.524502734090914e-9 2.0702442571824243e-9 5295/5777/3635/6464/5290/1437/7534/6776/7316/3055/6850/867/3567/3558/4067/3717/29760/2534/6654/6233/2885/1398/7409/7311/5293/5296/6777/1399/5781/7314 30 Avian_infectious_bronchitis_virus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 38/2292 69/10654 1.0525935146571541e-9 4.971824686252941e-9 2.2749221537383064e-9 3303/6118/5903/573/7175/9631/7531/5594/3308/10049/545/472/3337/3313/10808/3305/9532/4927/79902/6119/2932/57805/3310/3309/7266/9531/3306/9972/23411/8021/9529/6117/6396/3304/3312/55746/8480/5595 38 Avian_infectious_bronchitis_virus R-HSA-8868773 rRNA processing in the nucleus and cytosol 79/2292 195/10654 1.145477082341659e-9 5.391432769184063e-9 2.4669192139699487e-9 6158/5393/6138/6144/2091/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/23404/6217/55226/6230/6222/1454/6152/6136/27043/6125/51065/6154/6141/6202/6232/6160/55272/55781/6155/6175/6218/6209/10200/6231/6229/11224/6205/6130/6142/6204/23481/140801/6156/6143/51013/6181/6124/6207/10969/6233/7311/6223/26168/11340/6188/6189/51010/26354/6135/6201/56915/1453/9045/6187/4691/23016/6168/6208/54512/6137/10813/118460/6122/22894 79 Avian_infectious_bronchitis_virus R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 31/2292 51/10654 1.3555563886209423e-9 6.357750386067237e-9 2.9090702335490202e-9 5321/11258/1783/51807/93661/5050/347688/55860/830/7277/10381/10671/1780/1781/8398/8655/84516/1639/832/10121/636/7846/51143/10540/10383/84790/140735/7280/829/51164/1778 31 Avian_infectious_bronchitis_virus R-HSA-381042 PERK regulates gene expression 23/2292 32/10654 1.4769729269589134e-9 6.878769016465989e-9 3.1474689904645235e-9 5393/4802/23404/5073/1051/3576/468/4800/8894/3309/4801/51013/6347/11340/467/51010/56915/8570/23016/54512/118460/167227/22894 23 Avian_infectious_bronchitis_virus R-HSA-397795 G-protein beta:gamma signalling 23/2292 32/10654 1.4769729269589134e-9 6.878769016465989e-9 3.1474689904645235e-9 2788/54331/59345/207/10681/51764/94235/55970/2792/2793/10000/2785/2783/2784/2782/998/695/2786/208/387/2791/2790/2787 23 Avian_infectious_bronchitis_virus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 22/2292 30/10654 1.8195318310017181e-9 8.414594917664415e-9 3.8502058300361126e-9 6118/7320/5982/8450/7316/9978/5111/6119/1642/5985/7398/5984/57599/6233/7311/5983/6117/5981/10714/7314/51514/8451 22 Avian_infectious_bronchitis_virus R-HSA-8848021 Signaling by PTK6 32/2292 54/10654 1.8256891375413033e-9 8.414594917664415e-9 3.8502058300361126e-9 120892/1017/1019/4893/1796/207/2909/9021/2069/27043/1027/898/3091/2064/5921/7316/1950/6774/867/2908/595/2066/6233/1398/9844/7311/2034/387/1956/3845/3265/7314 32 Avian_infectious_bronchitis_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 32/2292 54/10654 1.8256891375413033e-9 8.414594917664415e-9 3.8502058300361126e-9 120892/1017/1019/4893/1796/207/2909/9021/2069/27043/1027/898/3091/2064/5921/7316/1950/6774/867/2908/595/2066/6233/1398/9844/7311/2034/387/1956/3845/3265/7314 32 Avian_infectious_bronchitis_virus R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13/2292 13/10654 2.0582549693259355e-9 9.453777997041883e-9 4.325697376550696e-9 7531/7532/10971/7533/2810/11200/7534/891/983/995/1111/7465/7529 13 Avian_infectious_bronchitis_virus R-HSA-163685 Integration of energy metabolism 51/2292 108/10654 2.2617897453605336e-9 1.0352934504536875e-8 4.737117969121899e-9 2788/5563/54331/59345/2770/1131/51422/10681/51764/112/94235/114/3708/108/2769/150/113/55970/2194/111/107/3709/2792/152/5519/2793/6794/2785/2783/2784/2782/3630/6514/2786/2771/9370/8826/2182/5518/3710/196883/115/5565/9630/2791/109/6513/2790/5515/2787/5516 51 Avian_infectious_bronchitis_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 156/2292 473/10654 2.276813957123855e-9 1.0386014352359503e-8 4.752254077774737e-9 5295/54106/5777/627/5590/4893/8065/6464/857/5290/3667/85440/5335/5241/1499/2904/5340/26469/5747/4690/5782/3815/5430/7424/10048/10273/207/7422/5594/10193/2069/3315/5908/3082/3178/51741/4318/3708/2064/382/57761/5921/58513/6778/348/6696/6776/9306/7316/1500/1950/9611/9047/3185/6774/11059/5289/4233/4734/3709/10413/6772/6714/2099/8651/3910/1281/5519/5598/1432/4208/867/5159/4670/2567/4067/3717/2247/4914/55824/10000/9146/3320/6455/2335/2534/4846/6195/3728/8471/5771/1445/1111/2264/5603/3630/998/2066/83737/3481/3925/6285/208/6654/30011/6233/2885/1398/5867/3187/7410/5580/2475/7409/1385/9844/6196/7311/3932/3479/1759/5518/1213/3791/387/3710/1956/1211/60/8851/5296/581/6197/3845/5600/6777/3265/1399/6300/1020/5781/7057/1278/3480/5663/10254/51231/7529/5156/10787/7314/5595/5515/6387/5516/5607 156 Avian_infectious_bronchitis_virus R-HSA-418217 G beta:gamma signalling through PLC beta 17/2292 20/10654 2.5049690128596124e-9 1.138777721887032e-8 5.210623525941138e-9 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Avian_infectious_bronchitis_virus R-HSA-912631 Regulation of signaling by CBL 18/2292 22/10654 2.736876032668707e-9 1.239972406637659e-8 5.673652785231584e-9 5295/5290/7316/3055/6850/867/4067/29760/2534/6233/2885/1398/7409/7311/5293/5296/1399/7314 18 Avian_infectious_bronchitis_virus R-HSA-72312 rRNA processing 81/2292 205/10654 2.86904478921022e-9 1.295446664145089e-8 5.927482365576155e-9 60528/6158/5393/6138/6144/2091/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/23404/6217/55226/6230/6222/1454/6152/6136/27043/6125/51065/6154/6141/6202/6232/6160/55272/55781/6155/6175/6218/54931/6209/10200/6231/6229/11224/6205/6130/6142/6204/23481/140801/6156/6143/51013/6181/6124/6207/10969/6233/7311/6223/26168/11340/6188/6189/51010/26354/6135/6201/56915/1453/9045/6187/4691/23016/6168/6208/54512/6137/10813/118460/6122/22894 81 Avian_infectious_bronchitis_virus R-HSA-69618 Mitotic Spindle Checkpoint 52/2292 112/10654 3.3221893913346026e-9 1.4949852261005712e-8 6.84049664858725e-9 5905/11130/5903/11065/246184/1783/1058/7321/991/8697/9212/6232/332/1780/8881/1781/5501/8655/51433/79902/3796/5519/1062/699/119504/51143/51529/7324/64682/29945/10393/11004/5527/51434/701/7514/9184/5518/25906/5347/84643/29882/6396/9793/10726/81930/55746/140735/996/5515/1778/5516 52 Avian_infectious_bronchitis_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 32/2292 55/10654 3.4688256967815256e-9 1.5557157670414112e-8 7.118377027951457e-9 1147/834/596/351/4790/6885/842/58484/7295/841/7316/7335/5970/7128/1432/598/10628/5603/10454/83737/3654/7189/6233/3326/7311/114548/5600/7334/1540/3551/6300/7314 32 Avian_infectious_bronchitis_virus R-HSA-163359 Glucagon signaling in metabolic regulation 23/2292 33/10654 3.880623020824227e-9 1.734560356959017e-8 7.936703387697731e-9 2788/54331/59345/51764/112/94235/114/108/113/55970/111/107/2785/2783/2784/2782/2786/196883/115/2791/109/2790/2787 23 Avian_infectious_bronchitis_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 33/2292 58/10654 4.3358676476549e-9 1.9060645896621542e-8 8.721443001536172e-9 8454/8841/142678/2648/9734/892/23462/51564/6500/10013/7316/9978/9611/9759/9612/1024/4609/10014/22938/8850/1387/26508/2033/55294/3066/3065/9794/6233/7311/3516/4851/5663/7314 33 Avian_infectious_bronchitis_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 33/2292 58/10654 4.3358676476549e-9 1.9060645896621542e-8 8.721443001536172e-9 8454/8841/142678/2648/9734/892/23462/51564/6500/10013/7316/9978/9611/9759/9612/1024/4609/10014/22938/8850/1387/26508/2033/55294/3066/3065/9794/6233/7311/3516/4851/5663/7314 33 Avian_infectious_bronchitis_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 33/2292 58/10654 4.3358676476549e-9 1.9060645896621542e-8 8.721443001536172e-9 8454/8841/142678/2648/9734/892/23462/51564/6500/10013/7316/9978/9611/9759/9612/1024/4609/10014/22938/8850/1387/26508/2033/55294/3066/3065/9794/6233/7311/3516/4851/5663/7314 33 Avian_infectious_bronchitis_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 33/2292 58/10654 4.3358676476549e-9 1.9060645896621542e-8 8.721443001536172e-9 8454/8841/142678/2648/9734/892/23462/51564/6500/10013/7316/9978/9611/9759/9612/1024/4609/10014/22938/8850/1387/26508/2033/55294/3066/3065/9794/6233/7311/3516/4851/5663/7314 33 Avian_infectious_bronchitis_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 33/2292 58/10654 4.3358676476549e-9 1.9060645896621542e-8 8.721443001536172e-9 8454/8841/142678/2648/9734/892/23462/51564/6500/10013/7316/9978/9611/9759/9612/1024/4609/10014/22938/8850/1387/26508/2033/55294/3066/3065/9794/6233/7311/3516/4851/5663/7314 33 Avian_infectious_bronchitis_virus R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 27/2292 43/10654 5.7406435833851274e-9 2.5153083069305887e-8 1.1509115771398852e-8 2788/54331/59345/10681/51764/112/94235/114/108/113/8766/55970/111/107/2792/2793/2785/2783/2784/2782/2786/196883/115/2791/109/2790/2787 27 Avian_infectious_bronchitis_virus R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 21/2292 29/10654 6.271577161106837e-9 2.7389314028178055e-8 1.2532331928493041e-8 2308/2309/4303/23410/4287/6720/847/114907/5443/84676/4089/4088/2908/4852/3630/3066/3065/6648/4087/25942/10891 21 Avian_infectious_bronchitis_virus R-HSA-1538133 G0 and Early G1 20/2292 27/10654 7.650374300738432e-9 3.33016293090967e-8 1.5237587616537847e-8 1017/9134/7027/7153/898/4149/5934/1869/1875/993/890/983/5933/5111/4609/5928/1874/3065/8900/1859 20 Avian_infectious_bronchitis_virus R-HSA-5696400 Dual Incision in GG-NER 26/2292 41/10654 8.135905545546891e-9 3.5299759565695306e-8 1.6151857743430996e-8 6118/5982/8450/7316/9978/5111/1643/6119/1642/2965/5985/142/2068/2071/5984/6233/2067/51426/2968/7311/5983/6117/5981/10714/7314/8451 26 Avian_infectious_bronchitis_virus R-HSA-5655862 Translesion synthesis by POLK 15/2292 17/10654 8.203263690935729e-9 3.536164154150935e-8 1.6180172635161938e-8 6118/5982/7316/5111/6119/51455/5985/5984/6233/51426/7311/5983/6117/5981/7314 15 Avian_infectious_bronchitis_virus R-HSA-5656121 Translesion synthesis by POLI 15/2292 17/10654 8.203263690935729e-9 3.536164154150935e-8 1.6180172635161938e-8 6118/5982/7316/11201/5111/6119/51455/5985/5984/6233/7311/5983/6117/5981/7314 15 Avian_infectious_bronchitis_virus R-HSA-1980143 Signaling by NOTCH1 38/2292 73/10654 8.69418649902488e-9 3.7356956182906906e-8 1.7093154441206812e-8 8454/8841/142678/2648/9734/892/23462/51564/6500/409/3091/10013/7316/9978/9611/8650/9759/9612/1024/4609/10014/22938/8850/1387/26508/2033/408/55294/3066/3065/83737/9794/6233/7311/3516/4851/5663/7314 38 Avian_infectious_bronchitis_virus R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 19/2292 25/10654 8.986665515354493e-9 3.848951275386554e-8 1.7611370226401256e-8 1017/902/2305/51400/891/993/890/4331/983/5519/995/8900/7514/5518/5347/7465/1022/5515/5516 19 Avian_infectious_bronchitis_virus R-HSA-8986944 Transcriptional Regulation by MECP2 34/2292 62/10654 9.2182543835464415e-009 3.9354855252832884e-8 1.8007318785672705e-8 818/27161/627/8841/2290/5468/2904/4986/9212/57690/27327/6657/192670/54487/9611/28996/2874/4233/9612/5775/4988/4208/3064/5728/192669/3066/3065/3654/23112/1385/25942/4343/6750/26523 34 Avian_infectious_bronchitis_virus R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 12/2292 12/10654 9.606995343669582e-9 4.088344344334787e-8 1.8706743917890328e-8 23368/8793/3486/355/8794/124446/8797/7157/8626/7161/7159/8795 12 Avian_infectious_bronchitis_virus R-HSA-500657 Presynaptic function of Kainate receptors 17/2292 21/10654 1.0500342807960076e-8 4.454285547835294e-8 2.038115483006666e-8 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Avian_infectious_bronchitis_virus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 39/2292 77/10654 1.5131335036509138e-8 6.398393101152436e-8 2.9276668291190612e-8 1912/5903/7175/9631/1029/7486/8535/51564/6045/51588/80012/6613/6996/1911/641/6672/4927/79902/9656/7341/84733/57332/142/7329/5371/8924/672/9972/6612/9063/8021/6117/6396/648/55746/8480/7508/6015/8554 39 Avian_infectious_bronchitis_virus R-HSA-73762 RNA Polymerase I Transcription Initiation 28/2292 47/10654 1.6104468778630573e-8 6.788339371245546e-8 3.1060917464447375e-8 902/9015/2648/2074/9112/9219/9014/5931/51082/4331/9013/1108/8850/5928/57459/2965/54815/2068/3066/3065/2071/1107/2968/57504/6908/53615/1022/10919 28 Avian_infectious_bronchitis_virus R-HSA-1236394 Signaling by ERBB4 32/2292 58/10654 2.0657612036319142e-8 8.680107013368169e-8 3.971694294879224e-8 5295/4893/6464/5290/5241/2069/51741/348/6776/7316/1950/9611/11059/4734/10413/6714/2099/2567/2066/83737/3925/6285/6654/6233/2885/7311/1956/3845/3265/5663/7314/6387 32 Avian_infectious_bronchitis_virus R-HSA-170670 Adenylate cyclase inhibitory pathway 13/2292 14/10654 2.30849126796487e-8 9.63921745745833e-8 4.410547580107771e-8 2770/112/114/108/113/111/107/346562/2771/196883/115/109/2773 13 Avian_infectious_bronchitis_virus R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 13/2292 14/10654 2.30849126796487e-8 9.63921745745833e-8 4.410547580107771e-8 23368/79370/9540/332/64065/5876/7157/8626/604/7161/7159/10397/5875 13 Avian_infectious_bronchitis_virus R-HSA-110312 Translesion synthesis by REV1 14/2292 16/10654 3.3878505466901435e-8 1.410192790059772e-7 6.452517982018398e-8 6118/5982/7316/5111/6119/51455/5985/5984/6233/7311/5983/6117/5981/7314 14 Avian_infectious_bronchitis_virus R-HSA-1433557 Signaling by SCF-KIT 26/2292 43/10654 3.420130429820775e-8 1.419194309196658e-7 6.493705587362612e-8 5295/5777/4893/5290/3815/4318/6776/9306/6774/6772/6714/8651/867/4067/3717/2534/1111/6654/2885/7409/3932/5296/3845/6777/3265/5781 26 Avian_infectious_bronchitis_virus R-HSA-5696394 DNA Damage Recognition in GG-NER 24/2292 38/10654 3.460553191019238e-8 1.431508338645225e-7 6.550050008499965e-8 9318/86/8450/7316/9978/64708/1643/10980/1642/10920/142/10987/6233/2873/7311/60/8533/5886/50813/7508/7314/51138/8451/7528 24 Avian_infectious_bronchitis_virus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 21/2292 31/10654 4.1162275410322413e-8 1.697465970481407e-7 7.766973264649399e-8 3725/5601/5594/5519/5598/1432/4208/5602/6195/1385/2353/6196/5518/1386/6197/5599/5600/51231/5595/5515/5516 21 Avian_infectious_bronchitis_virus R-HSA-9614399 Regulation of localization of FOXO transcription factors 11/2292 11/10654 4.482562535847227e-8 1.842831264737193e-7 8.432110813045954e-8 2308/2309/7532/207/10971/4303/2810/7534/10000/208/7529 11 Avian_infectious_bronchitis_virus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 30/2292 54/10654 4.621083980187555e-8 1.8939334958799458e-7 8.665935626003545e-8 10450/9318/902/2074/5430/8450/7316/9978/4331/64708/10980/1161/1642/2965/10920/2033/2068/10987/2071/6233/2873/2968/7311/8533/7874/1022/50813/7314/51138/8451 30 Avian_infectious_bronchitis_virus R-HSA-162587 HIV Life Cycle 62/2292 152/10654 5.173416404603344e-8 2.1138008131692194e-7 9.671966736407286e-8 6884/6875/5905/5903/7852/902/7175/9631/3159/5430/6874/7520/6878/6749/7316/6872/4331/4836/9397/4927/8148/79902/6879/9150/23327/54457/8812/83860/2965/128866/905/2068/2071/6873/6233/2968/7514/1025/7311/9972/6881/51616/6880/6908/8021/7251/11198/6396/904/6883/1104/51497/2547/6882/138474/1022/55746/1234/8178/8480/6877/7314 62 Avian_infectious_bronchitis_virus R-HSA-166520 Signaling by NTRKs 46/2292 101/10654 5.517995426805122e-8 2.2408444843001287e-7 1.0253271348267543e-7 5295/627/4893/6464/5290/3667/5335/2904/5594/6774/6714/5519/5598/1432/4208/4914/2534/6195/5603/6654/2885/1398/1385/6196/1759/5518/1213/387/1211/8851/5296/581/6197/3845/5600/3265/1399/6300/1020/5781/51231/7529/5595/5515/5516/5607 46 Avian_infectious_bronchitis_virus R-HSA-2219528 PI3K/AKT Signaling in Cancer 46/2292 101/10654 5.517995426805122e-8 2.2408444843001287e-7 1.0253271348267543e-7 5295/1147/2308/5290/3667/2309/842/3815/207/2069/4303/1027/7249/3082/930/941/2064/1950/4233/1026/6714/2099/2932/5159/2247/3164/10000/2534/5728/2264/2066/942/208/2885/2475/7409/1385/3932/5293/1956/118788/5296/5781/5156/940/4193 46 Avian_infectious_bronchitis_virus R-HSA-177929 Signaling by EGFR 28/2292 49/10654 5.705323890407394e-8 2.3098758121649386e-7 1.0569133042859963e-7 5295/4893/6464/5290/5335/5782/2069/58513/7316/1950/6714/867/55824/9146/6455/1445/998/6654/30011/6233/2885/7311/1956/3845/3265/5781/10254/7314 28 Avian_infectious_bronchitis_virus R-HSA-187037 Signaling by NTRK1 (TRKA) 39/2292 80/10654 5.838531973167902e-8 2.356643814624135e-7 1.078312603656847e-7 5295/4893/6464/5290/3667/5335/5594/6774/6714/5519/5598/1432/4208/4914/6195/5603/6654/2885/1398/1385/6196/1759/5518/1213/387/1211/5296/6197/3845/5600/3265/1399/6300/51231/7529/5595/5515/5516/5607 39 Avian_infectious_bronchitis_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 38/2292 78/10654 8.809257354724372e-8 3.5449941983362125e-7 1.6220575634871717e-7 1147/3665/351/4790/7321/4214/841/7706/7323/7316/5970/4792/4793/3093/3146/7322/7128/1387/843/2033/6288/54941/83737/9246/7189/6285/51191/6233/10010/7311/55593/7318/5300/9641/1540/3551/3456/7314 38 Avian_infectious_bronchitis_virus R-HSA-1643713 Signaling by EGFR in Cancer 18/2292 25/10654 9.143341727650561e-8 3.6683527654308876e-7 1.6785018580563333e-7 5295/4893/6464/5290/5335/2069/7316/1950/867/3320/6654/6233/2885/7311/1956/3845/3265/7314 18 Avian_infectious_bronchitis_virus R-HSA-2871796 FCERI mediated MAPK activation 21/2292 32/10654 9.545283897236282e-8 3.806682081173272e-7 1.741796210683835e-7 3725/5601/4893/6464/5335/5336/5594/4214/6850/4067/5602/5609/6654/2885/7410/7409/2353/3845/5599/3265/5595 21 Avian_infectious_bronchitis_virus R-HSA-5656169 Termination of translesion DNA synthesis 21/2292 32/10654 9.545283897236282e-8 3.806682081173272e-7 1.741796210683835e-7 6118/5982/7706/7316/11201/5111/9100/6119/51455/5985/5984/9246/6233/51426/7311/7318/5983/6117/5981/10714/7314 21 Avian_infectious_bronchitis_virus R-HSA-209560 NF-kB is activated and signals survival 12/2292 13/10654 1.0019187983579326e-7 3.9837487743664664e-7 1.822815347208933e-7 4804/4790/8878/7316/5970/4792/3654/7189/6233/7311/3551/7314 12 Avian_infectious_bronchitis_virus R-HSA-400253 Circadian Clock 35/2292 70/10654 1.249587790946379e-7 4.953723028394574e-7 2.2666395080136387e-7 8454/26224/8945/8841/10135/1454/6500/3091/200186/6720/7316/9611/5469/5501/8553/4208/1387/150094/2908/2033/5499/10498/6233/1385/7311/10499/23054/8864/1386/23411/1453/8648/10891/7314/5054 35 Avian_infectious_bronchitis_virus R-HSA-389513 CTLA4 inhibitory signaling 16/2292 21/10654 1.3381598584560933e-7 5.273458377110996e-7 2.4129385177392654e-7 207/941/6714/5519/4067/10000/2534/942/208/5527/3932/5518/5781/1493/5515/5516 16 Avian_infectious_bronchitis_virus R-HSA-9008059 Interleukin-37 signaling 16/2292 21/10654 1.3381598584560933e-7 5.273458377110996e-7 2.4129385177392654e-7 5778/834/5777/26469/5782/5783/27178/25930/6774/5780/5775/4088/84867/5771/5784/5781 16 Avian_infectious_bronchitis_virus R-HSA-111447 Activation of BAD and translocation to mitochondria 13/2292 15/10654 1.3874536341386568e-7 5.403766785592664e-7 2.472562801373599e-7 596/7531/7532/207/10971/7533/2810/7534/10000/5534/208/637/7529 13 Avian_infectious_bronchitis_virus R-HSA-5637810 Constitutive Signaling by EGFRvIII 13/2292 15/10654 1.3874536341386568e-7 5.403766785592664e-7 2.472562801373599e-7 5295/4893/6464/5290/5335/1950/867/3320/6654/2885/1956/3845/3265 13 Avian_infectious_bronchitis_virus R-HSA-5637812 Signaling by EGFRvIII in Cancer 13/2292 15/10654 1.3874536341386568e-7 5.403766785592664e-7 2.472562801373599e-7 5295/4893/6464/5290/5335/1950/867/3320/6654/2885/1956/3845/3265 13 Avian_infectious_bronchitis_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 13/2292 15/10654 1.3874536341386568e-7 5.403766785592664e-7 2.472562801373599e-7 54106/3665/4615/7316/7335/3654/7189/6233/51311/7311/7334/51284/7314 13 Avian_infectious_bronchitis_virus R-HSA-162599 Late Phase of HIV Life Cycle 57/2292 139/10654 1.4272647479031475e-7 5.542614123052456e-7 2.5360941814820394e-7 6884/6875/5905/5903/902/7175/9631/5430/6874/6878/6749/7316/6872/4331/4836/9397/4927/8148/79902/6879/9150/23327/54457/8812/83860/2965/128866/905/2068/2071/6873/6233/2968/7514/1025/7311/9972/6881/51616/6880/6908/8021/7251/11198/6396/904/6883/1104/51497/6882/138474/1022/55746/8178/8480/6877/7314 57 Avian_infectious_bronchitis_virus R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 48/2292 110/10654 1.4643032711014768e-7 5.669918479962696e-7 2.594343922789948e-7 1017/3725/1019/11065/4790/246184/1029/7321/8697/5594/1027/1051/79813/3576/8881/7316/890/6774/5970/1026/51433/1031/5598/3552/1021/119504/6195/8900/51529/7324/64682/29945/10393/6233/51434/2353/1030/51343/6196/7311/25906/6197/29882/3569/10919/7314/996/5595 48 Avian_infectious_bronchitis_virus R-HSA-8953750 Transcriptional Regulation by E2F6 22/2292 35/10654 1.4730121712453245e-7 5.687107861155861e-7 2.6022091446256074e-7 5888/7027/2146/6045/80012/5931/79813/4149/1869/1911/5928/23512/1111/672/5932/8726/648/317/23429/10919/6015/6241 22 Avian_infectious_bronchitis_virus R-HSA-110320 Translesion Synthesis by POLH 15/2292 19/10654 1.4955764017569712e-7 5.757536899249381e-7 2.6344348543270045e-7 6118/5982/7316/5111/7415/6119/5985/25898/5984/6233/7311/5983/6117/5981/7314 15 Avian_infectious_bronchitis_virus R-HSA-450385 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA 14/2292 17/10654 1.536963004214075e-7 5.899811877847688e-7 2.699534595601242e-7 5393/23404/207/51013/11340/51010/54464/56915/23016/54512/118460/167227/7529/22894 14 Avian_infectious_bronchitis_virus R-HSA-350054 Notch-HLH transcription pathway 19/2292 28/10654 1.7797248428056596e-7 6.812050260394076e-7 3.11694096789013e-7 8841/2648/9734/51564/10013/4854/9611/9759/9612/10014/22938/8850/1387/4855/3066/3065/9794/3516/4851 19 Avian_infectious_bronchitis_virus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 33/2292 65/10654 1.7944657218290077e-7 6.829223832789251e-7 3.124798956207505e-7 10450/6118/902/2074/5430/7515/5982/8450/7316/9978/4331/5111/6119/1161/1642/2965/5985/2033/2068/2071/5984/6233/51426/2968/7311/5983/6117/5981/10714/7874/1022/7314/8451 33 Avian_infectious_bronchitis_virus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 33/2292 65/10654 1.7944657218290077e-7 6.829223832789251e-7 3.124798956207505e-7 2176/3725/4436/8621/902/5430/6749/4292/545/472/4331/1643/5395/9150/9656/8812/2965/51755/905/2068/1111/2071/7157/2968/672/1025/2353/1386/11198/904/51497/1022/8178 33 Avian_infectious_bronchitis_virus R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 10/2292 10/10654 2.0908148830656406e-7 7.852218480625871e-7 3.5928832782380117e-7 5563/51422/53632/1432/5571/5600/5564/6300/5565/10891 10 Avian_infectious_bronchitis_virus R-HSA-390450 Folding of actin by CCT/TriC 10/2292 10/10654 2.0908148830656406e-7 7.852218480625871e-7 3.5928832782380117e-7 10694/10575/7203/10576/908/6950/10574/60/22948/10693 10 Avian_infectious_bronchitis_virus R-HSA-450341 Activation of the AP-1 family of transcription factors 10/2292 10/10654 2.0908148830656406e-7 7.852218480625871e-7 3.5928832782380117e-7 3725/5601/5594/1432/5602/2353/1386/5599/5600/5595 10 Avian_infectious_bronchitis_virus R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 10/2292 10/10654 2.0908148830656406e-7 7.852218480625871e-7 3.5928832782380117e-7 2308/2309/4303/23410/7295/8850/1387/10628/2033/23411 10 Avian_infectious_bronchitis_virus R-HSA-9022692 Regulation of MECP2 expression and activity 21/2292 33/10654 2.0927459163830214e-7 7.852218480625871e-7 3.5928832782380117e-7 818/27161/8841/2290/9212/57690/27327/192670/9611/28996/2874/9612/3064/192669/3066/3065/23112/1385/25942/4343/26523 21 Avian_infectious_bronchitis_virus R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 18/2292 26/10654 2.3725107412756768e-7 8.87692221173933e-7 4.061749613242511e-7 80010/83990/5888/9156/1763/7486/10111/675/472/580/116028/641/10524/4683/79728/672/5932/7156 18 Avian_infectious_bronchitis_virus R-HSA-4420097 VEGFA-VEGFR2 Pathway 44/2292 99/10654 2.5444093693865587e-7 9.493426554685984e-7 4.343839082632516e-7 5295/5590/4893/857/5290/5335/1499/5747/4690/207/7422/3315/3708/57761/5921/1500/9047/3709/6714/1432/10000/3320/2534/4846/3728/5603/998/208/1398/7410/5580/2475/7409/9844/3791/387/3710/60/5296/3845/5600/3265/6300/10787 44 Avian_infectious_bronchitis_virus R-HSA-6782135 Dual incision in TC-NER 33/2292 66/10654 2.85271724663587e-7 1.0614020593628434e-6 4.85658125787171e-7 10450/6118/902/2074/5430/5982/8450/7316/9978/4331/5111/6119/1161/1642/2965/5985/2033/2068/2071/5984/6233/2067/51426/2968/7311/5983/6117/5981/10714/7874/1022/7314/8451 33 Avian_infectious_bronchitis_virus R-HSA-168638 NOD1/2 Signaling Pathway 22/2292 36/10654 3.0188360499416056e-7 1.1200806736830691e-6 5.125072783803518e-7 1147/834/6885/842/841/7316/7335/7128/1432/5603/10454/83737/3654/7189/6233/7311/5600/7334/1540/3551/6300/7314 22 Avian_infectious_bronchitis_virus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 23/2292 39/10654 4.037547033107531e-7 1.488719109949652e-6 6.811825230447673e-7 6118/5982/7706/7316/11201/5111/9100/7415/6119/51455/5985/25898/5984/9246/6233/51426/7311/7318/5983/6117/5981/10714/7314 23 Avian_infectious_bronchitis_virus R-HSA-167161 HIV Transcription Initiation 26/2292 47/10654 4.090624581393188e-7 1.488719109949652e-6 6.811825230447673e-7 6884/6875/902/5430/6874/6878/6872/4331/8148/6879/54457/83860/2965/2068/2071/6873/2968/6881/51616/6880/6908/6883/6882/138474/1022/6877 26 Avian_infectious_bronchitis_virus R-HSA-167162 RNA Polymerase II HIV Promoter Escape 26/2292 47/10654 4.090624581393188e-7 1.488719109949652e-6 6.811825230447673e-7 6884/6875/902/5430/6874/6878/6872/4331/8148/6879/54457/83860/2965/2068/2071/6873/2968/6881/51616/6880/6908/6883/6882/138474/1022/6877 26 Avian_infectious_bronchitis_virus R-HSA-73776 RNA Polymerase II Promoter Escape 26/2292 47/10654 4.090624581393188e-7 1.488719109949652e-6 6.811825230447673e-7 6884/6875/902/5430/6874/6878/6872/4331/8148/6879/54457/83860/2965/2068/2071/6873/2968/6881/51616/6880/6908/6883/6882/138474/1022/6877 26 Avian_infectious_bronchitis_virus R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 26/2292 47/10654 4.090624581393188e-7 1.488719109949652e-6 6.811825230447673e-7 6884/6875/902/5430/6874/6878/6872/4331/8148/6879/54457/83860/2965/2068/2071/6873/2968/6881/51616/6880/6908/6883/6882/138474/1022/6877 26 Avian_infectious_bronchitis_virus R-HSA-75953 RNA Polymerase II Transcription Initiation 26/2292 47/10654 4.090624581393188e-7 1.488719109949652e-6 6.811825230447673e-7 6884/6875/902/5430/6874/6878/6872/4331/8148/6879/54457/83860/2965/2068/2071/6873/2968/6881/51616/6880/6908/6883/6882/138474/1022/6877 26 Avian_infectious_bronchitis_virus R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 26/2292 47/10654 4.090624581393188e-7 1.488719109949652e-6 6.811825230447673e-7 6884/6875/902/5430/6874/6878/6872/4331/8148/6879/54457/83860/2965/2068/2071/6873/2968/6881/51616/6880/6908/6883/6882/138474/1022/6877 26 Avian_infectious_bronchitis_virus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 40/2292 88/10654 4.285354944322275e-7 1.5553386337431253e-6 7.116651406174093e-7 8454/115106/8945/22995/11258/22981/7531/4659/203068/54801/7532/1454/6500/7277/1781/7316/891/8655/983/1639/6790/10121/23291/7846/7283/3320/10540/6233/7311/54930/5518/10383/55835/5347/9662/1453/9793/8481/7314/1778 40 Avian_infectious_bronchitis_virus R-HSA-167172 Transcription of the HIV genome 35/2292 73/10654 4.622721169448525e-7 1.6732240754634334e-6 7.656051364733113e-7 6884/6875/902/5430/6874/6878/6749/6872/4331/8148/6879/9150/54457/8812/83860/2965/905/2068/2071/6873/2968/1025/6881/51616/6880/6908/11198/904/6883/51497/6882/138474/1022/8178/6877 35 Avian_infectious_bronchitis_virus R-HSA-8876384 Listeria monocytogenes entry into host cells 15/2292 20/10654 4.786469301091603e-7 1.7277986745403834e-6 7.905764442538976e-7 1499/7316/1500/4233/6714/867/999/9146/6455/30011/6233/2885/7311/10254/7314 15 Avian_infectious_bronchitis_virus R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 24/2292 42/10654 5.092154199401e-7 1.83317551178436e-6 8.387929676964948e-7 2788/54331/59345/10681/51764/112/94235/114/3708/55970/111/3709/2792/2793/2785/2783/2784/2782/2786/8826/3710/2791/2790/2787 24 Avian_infectious_bronchitis_virus R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 14/2292 18/10654 5.538671219975135e-7 1.9885471873333908e-6 9.098852706385596e-7 4893/5594/4314/5598/6195/6654/2885/1385/6196/1956/6197/3845/3265/5595 14 Avian_infectious_bronchitis_virus R-HSA-3371568 Attenuation phase 12/2292 14/10654 5.628336827726613e-7 2.015307702831142e-6 9.221298877344961e-7 3303/3337/3305/1387/3320/2033/3326/3306/3304/3312/2288/10728 12 Avian_infectious_bronchitis_virus R-HSA-429914 Deadenylation-dependent mRNA decay 29/2292 56/10654 5.786182186056097e-7 2.0607472384563425e-6 9.429213300665579e-7 5393/9924/23404/5073/4849/4850/26986/219988/9337/25904/246175/4848/23019/1981/51013/1975/55571/11340/51010/54464/57472/56915/85456/29883/23016/54512/118460/167227/22894 29 Avian_infectious_bronchitis_virus R-HSA-977443 GABA receptor activation 29/2292 56/10654 5.786182186056097e-7 2.0607472384563425e-6 9.429213300665579e-7 2788/54331/2770/2550/112/94235/114/108/113/55970/111/107/9568/2792/346562/2793/2567/2785/2783/2784/2782/2786/2771/196883/115/109/2773/2790/2787 29 Avian_infectious_bronchitis_virus R-HSA-1295596 Spry regulation of FGF signaling 13/2292 16/10654 5.931684145173785e-7 2.0957568385600745e-6 9.589404216265871e-7 5594/7316/6714/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 13 Avian_infectious_bronchitis_virus R-HSA-193639 p75NTR signals via NF-kB 13/2292 16/10654 5.931684145173785e-7 2.0957568385600745e-6 9.589404216265871e-7 4804/4790/8878/4615/7316/5970/4792/3654/7189/6233/7311/3551/7314 13 Avian_infectious_bronchitis_virus R-HSA-9614657 FOXO-mediated transcription of cell death genes 13/2292 16/10654 5.931684145173785e-7 2.0957568385600745e-6 9.589404216265871e-7 2308/27113/2309/10018/4802/4303/4800/10370/1387/6794/2033/4801/604 13 Avian_infectious_bronchitis_virus R-HSA-2559580 Oxidative Stress Induced Senescence 51/2292 125/10654 7.696896344187293e-7 2.712239664142189e-6 1.2410200454704659e-6 1912/3725/1019/5601/5606/1029/7027/2146/8535/6045/57690/5594/27327/80012/5931/7295/192670/8550/7316/1869/1911/4194/1031/5928/1432/84733/5602/23512/1021/57332/192669/7157/23135/23112/5609/6233/2353/1030/7311/4343/8726/5599/648/5600/23466/26523/3456/7314/6015/5595/4193 51 Avian_infectious_bronchitis_virus R-HSA-9006335 Signaling by Erythropoietin 17/2292 25/10654 7.72706329219336e-7 2.715685568654764e-6 1.2425967632773103e-6 5295/4893/6464/5290/5335/5336/6776/4067/3717/6654/2885/7409/5293/3845/6777/3265/1399 17 Avian_infectious_bronchitis_virus R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 38/2292 84/10654 9.604593935603973e-7 3.357826541266271e-6 1.5364166013854682e-6 7124/1052/1019/8841/4790/5468/892/9440/6721/9862/1051/6720/6837/3952/688/9611/5469/1050/5970/9612/1024/9314/1387/10001/2033/9967/896/10498/9370/112950/10499/23054/7040/9412/51586/8202/8648/10891 38 Avian_infectious_bronchitis_virus R-HSA-674695 RNA Polymerase II Pre-transcription Events 38/2292 84/10654 9.604593935603973e-7 3.357826541266271e-6 1.5364166013854682e-6 6884/6875/902/6830/5430/6874/6878/79577/6749/6872/4331/8148/6879/9150/54457/8812/83860/2965/905/2068/2071/6873/2968/1025/6881/51616/6880/6908/11198/904/6883/51497/6882/138474/1022/8178/55840/6877 38 Avian_infectious_bronchitis_virus R-HSA-199418 Negative regulation of the PI3K/AKT network 46/2292 110/10654 1.1634586774323983e-6 4.056876854293075e-6 1.8562760381189275e-6 5295/5290/3667/90865/3815/207/5594/2069/3082/930/941/2064/57761/4615/1950/4233/6714/2099/5519/5159/2247/10000/2534/5728/2264/3630/2066/942/3654/7189/208/5527/2885/7409/3932/5293/5518/1956/118788/5296/5781/5156/940/5595/5515/5516 46 Avian_infectious_bronchitis_virus R-HSA-194138 Signaling by VEGF 45/2292 107/10654 1.2556045022941958e-6 4.36674986176467e-6 1.9980624071137545e-6 5295/5590/4893/857/5290/5335/1499/5747/4690/7424/207/7422/3315/3708/57761/5921/1500/9047/3709/6714/1432/10000/3320/2534/4846/3728/5603/998/208/1398/7410/5580/2475/7409/9844/3791/387/3710/60/5296/3845/5600/3265/6300/10787 45 Avian_infectious_bronchitis_virus R-HSA-201451 Signaling by BMP 18/2292 28/10654 1.2710852601893418e-6 4.397852566147781e-6 2.012293848427031e-6 4093/57154/9765/7321/6497/4086/658/64750/659/7323/93/4092/4089/92/650/657/4091/4090 18 Avian_infectious_bronchitis_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 20/2292 33/10654 1.2711510795547264e-6 4.397852566147781e-6 2.012293848427031e-6 1147/351/4790/6885/7316/7335/5970/4792/4793/3146/10454/6288/3654/7189/6285/6233/7311/7334/3551/7314 20 Avian_infectious_bronchitis_virus R-HSA-445717 Aquaporin-mediated transport 27/2292 52/10654 1.3221939767224562e-6 4.562596831591481e-6 2.087674700088089e-6 2788/54331/59345/10681/51764/112/94235/114/108/113/8766/55970/111/107/2792/2793/2785/2783/2784/2782/2786/196883/115/2791/109/2790/2787 27 Avian_infectious_bronchitis_virus R-HSA-5654743 Signaling by FGFR4 23/2292 41/10654 1.3742792162878156e-6 4.7300773025720165e-6 2.1643075376870537e-6 5295/4893/6464/5290/5335/5594/7316/6714/867/2247/2264/6654/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 23 Avian_infectious_bronchitis_virus R-HSA-8852135 Protein ubiquitination 36/2292 79/10654 1.488168731392261e-6 5.108867912923947e-6 2.3376280398158414e-6 11065/7319/7321/79139/65264/7320/10477/92912/79577/7336/7326/5591/7323/8239/7316/7317/54926/55236/56254/5111/7415/3093/7322/118424/7328/7324/6233/7327/7311/55284/27338/7334/7874/7332/997/7314 36 Avian_infectious_bronchitis_virus R-HSA-5619115 Disorders of transmembrane transporters 65/2292 176/10654 1.790481488968452e-6 6.130903196159327e-6 2.8052733922682554e-6 5718/5689/5684/5903/5720/7175/5682/9631/5700/122706/5707/79139/5690/285195/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/5695/5714/4927/7415/9861/79902/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/6514/5719/5704/6233/5716/7311/9972/8021/6396/213/5694/55746/5693/5721/5696/5691/8480/6513/7314 65 Avian_infectious_bronchitis_virus R-HSA-450513 Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA 13/2292 17/10654 2.0214527853292787e-6 6.886381355648592e-6 3.150952113893263e-6 5393/23404/51013/11340/51010/54464/56915/23016/54512/118460/167227/7529/22894 13 Avian_infectious_bronchitis_virus R-HSA-4655427 SUMOylation of DNA methylation proteins 13/2292 17/10654 2.0214527853292787e-6 6.886381355648592e-6 3.150952113893263e-6 1912/1788/8535/1786/6045/80012/1911/7341/84733/57332/7329/648/6015 13 Avian_infectious_bronchitis_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 36/2292 80/10654 2.1505150486443146e-6 7.307362359168947e-6 3.343577371549566e-6 3837/3838/5903/5335/7175/9631/2316/1982/7706/9470/7316/2317/4734/6772/4927/79902/6041/3840/6059/1981/7324/9246/51191/6233/7311/9972/7318/5610/5300/8021/6396/7334/55746/8480/7314/5595 36 Avian_infectious_bronchitis_virus R-HSA-1502540 Signaling by Activin 11/2292 13/10654 2.2584432717916004e-6 7.61832159746034e-6 3.48586075938797e-6 130399/91/93/3624/4089/92/4088/4087/3625/8928/10589 11 Avian_infectious_bronchitis_virus R-HSA-937039 IRAK1 recruits IKK complex 12/2292 15/10654 2.2591869602078335e-6 7.61832159746034e-6 3.48586075938797e-6 1147/7316/7335/57162/3654/7189/6233/7311/7334/3551/57161/7314 12 Avian_infectious_bronchitis_virus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 12/2292 15/10654 2.2591869602078335e-6 7.61832159746034e-6 3.48586075938797e-6 1147/7316/7335/57162/3654/7189/6233/7311/7334/3551/57161/7314 12 Avian_infectious_bronchitis_virus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 16/2292 24/10654 2.4731108355163023e-6 8.318645537645744e-6 3.806302960563368e-6 596/2309/5747/207/5594/2069/1027/1950/10000/595/208/7514/1385/2353/1956/5595 16 Avian_infectious_bronchitis_virus R-HSA-8863795 Downregulation of ERBB2 signaling 18/2292 29/10654 2.677020977717724e-6 8.981843683425713e-6 4.10975777833372e-6 8065/26469/5782/10273/207/10193/2069/2064/7316/1950/10000/3320/2066/208/6233/7311/1956/7314 18 Avian_infectious_bronchitis_virus R-HSA-4615885 SUMOylation of DNA replication proteins 24/2292 45/10654 2.747858923170943e-6 9.196351974029386e-6 4.207908797979307e-6 7150/5905/5903/7175/9631/9212/51588/7153/6613/332/6790/5111/4927/79902/7341/10401/7329/9972/6612/7155/8021/6396/55746/8480 24 Avian_infectious_bronchitis_virus R-HSA-422356 Regulation of insulin secretion 35/2292 78/10654 3.216629505565328e-6 1.0738221808052675e-5 4.913411116534296e-6 2788/54331/59345/2770/1131/10681/51764/112/94235/114/3708/2769/150/55970/111/3709/2792/152/2793/2785/2783/2784/2782/3630/6514/2786/2771/8826/2182/3710/9630/2791/6513/2790/2787 35 Avian_infectious_bronchitis_virus R-HSA-68877 Mitotic Prometaphase 71/2292 200/10654 3.2354396598897013e-6 1.0774014067432705e-5 4.929788323884572e-6 10844/115106/5905/11130/22995/5903/11258/22981/7531/1459/1783/1058/991/203068/54801/51807/7532/1454/9212/347688/1460/7277/10381/6232/332/1780/1781/891/5501/8655/1457/983/1639/10121/79902/3796/5519/1062/699/7846/7283/3320/80097/23397/51143/10540/11004/5527/701/7514/9184/54930/5518/10383/55835/5347/84790/84643/6396/9662/1453/9793/10726/81930/55746/8481/140735/7280/5515/1778/5516 71 Avian_infectious_bronchitis_virus R-HSA-1169408 ISG15 antiviral mechanism 33/2292 72/10654 3.4508980506967877e-6 1.146283342525716e-5 5.2449664558431295e-6 3837/3838/5903/5335/7175/9631/1982/7706/9470/7316/2317/4734/6772/4927/79902/3840/1981/7324/9246/51191/6233/7311/9972/7318/5610/5300/8021/6396/7334/55746/8480/7314/5595 33 Avian_infectious_bronchitis_virus R-HSA-5654741 Signaling by FGFR3 22/2292 40/10654 3.6431221047017258e-6 1.2071240406623628e-5 5.5233508735854915e-6 5295/4893/6464/5290/5335/5594/7316/6714/867/2247/6654/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 22 Avian_infectious_bronchitis_virus R-HSA-6806834 Signaling by MET 35/2292 79/10654 4.591541485021187e-6 1.5176013047266059e-5 6.943979417075272e-6 5295/4893/6464/5290/85440/5747/10048/5908/3082/382/7316/6774/4233/6714/3910/1281/867/9146/6455/2335/5771/6654/30011/6233/2885/1398/5867/7311/3845/3265/1399/5781/1278/10254/7314 35 Avian_infectious_bronchitis_virus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 21/2292 38/10654 5.480160619350711e-6 1.7899123481219833e-5 8.189973522701346e-6 7020/4435/7021/3815/7422/4869/51741/2064/5308/348/1026/2099/4609/10370/7341/1387/2033/7022/7329/1956/7528 21 Avian_infectious_bronchitis_virus R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 16/2292 25/10654 5.496052180044227e-6 1.7899123481219833e-5 8.189973522701346e-6 10694/51807/10575/7277/10381/7203/10576/908/6950/7846/10574/10383/84790/22948/10693/7280 16 Avian_infectious_bronchitis_virus R-HSA-429947 Deadenylation of mRNA 16/2292 25/10654 5.496052180044227e-6 1.7899123481219833e-5 8.189973522701346e-6 9924/5073/4849/4850/26986/9337/25904/246175/4848/23019/1981/1975/55571/57472/85456/29883 16 Avian_infectious_bronchitis_virus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 16/2292 25/10654 5.496052180044227e-6 1.7899123481219833e-5 8.189973522701346e-6 1147/2308/2309/842/207/4303/1027/7249/1026/2932/3164/10000/208/2475/1385/4193 16 Avian_infectious_bronchitis_virus R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 16/2292 25/10654 5.496052180044227e-6 1.7899123481219833e-5 8.189973522701346e-6 6118/7515/5982/7316/5111/6119/5985/5984/6233/51426/7311/5983/6117/5981/10714/7314 16 Avian_infectious_bronchitis_virus R-HSA-9006115 Signaling by NTRK2 (TRKB) 16/2292 25/10654 5.496052180044227e-6 1.7899123481219833e-5 8.189973522701346e-6 5295/627/4893/6464/5290/5335/2904/6714/2534/6654/2885/8851/3845/3265/1020/5781 16 Avian_infectious_bronchitis_virus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 42/2292 103/10654 7.225104525080012e-6 2.3472778603430676e-5 1.074027091147966e-5 5295/5290/3667/90865/3815/207/5594/2069/3082/930/941/2064/4615/1950/4233/6714/2099/5519/5159/2247/2534/2264/3630/2066/942/3654/7189/5527/2885/7409/3932/5293/5518/1956/118788/5296/5781/5156/940/5595/5515/5516 42 Avian_infectious_bronchitis_virus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 12/2292 16/10654 7.257242597279254e-6 2.3519822724029115e-5 1.0761796552246608e-5 57154/5590/7316/7046/2280/6233/7048/7311/56288/387/7040/7314 12 Avian_infectious_bronchitis_virus R-HSA-170660 Adenylate cyclase activating pathway 9/2292 10/10654 7.86716035479578e-6 2.5434605807252373e-5 1.1637930110952368e-5 112/114/108/113/111/107/196883/115/109 9 Avian_infectious_bronchitis_virus R-HSA-198323 AKT phosphorylates targets in the cytosol 11/2292 14/10654 8.47567843152774e-6 2.733560210846235e-5 1.2507755350718906e-5 1147/842/207/1027/7249/1026/2932/10000/208/23608/4193 11 Avian_infectious_bronchitis_virus R-HSA-3371511 HSF1 activation 10/2292 12/10654 8.94868792911838e-6 2.8722053786953455e-5 1.3142144098819385e-5 6118/7531/1915/10013/7415/6119/3320/3326/6117/10728 10 Avian_infectious_bronchitis_virus R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 10/2292 12/10654 8.94868792911838e-6 2.8722053786953455e-5 1.3142144098819385e-5 834/58484/55367/472/843/7157/8626/7161/839/317 10 Avian_infectious_bronchitis_virus R-HSA-381119 Unfolded Protein Response (UPR) 39/2292 94/10654 9.317173785053179e-6 2.9832873754064508e-5 1.3650414022130037e-5 4000/5393/6464/4802/23404/5073/7184/7094/1051/3576/468/84447/9570/22872/4800/1639/2081/55738/30827/11015/10954/8894/3309/4801/51013/6347/11340/467/51010/10106/56915/8570/23016/54512/118460/167227/9820/22894/7709 39 Avian_infectious_bronchitis_virus R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 22/2292 42/10654 1.0503819144963619e-5 3.355176762851688e-5 1.5352041612858604e-5 9070/51176/8945/6662/1487/1499/207/5929/6736/6657/7534/7316/3065/208/57680/6233/7514/7311/331/6659/7314/4221 22 Avian_infectious_bronchitis_virus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 32/2292 72/10654 1.0745023738572737e-5 3.4240123492293984e-5 1.566700766717103e-5 5563/9371/7531/11127/4627/51807/7532/207/10971/347688/51422/7533/2810/7277/53632/10381/7534/8766/4641/5571/7846/208/5867/9882/10383/60/84790/5564/5565/22920/7280/7529 32 Avian_infectious_bronchitis_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 14/2292 21/10654 1.0827359618685743e-5 3.442015038684823e-5 1.5749381281796372e-5 4893/4790/3384/5970/1387/4067/2534/2033/3385/5894/30835/5971/3845/3265 14 Avian_infectious_bronchitis_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 19/2292 34/10654 1.2390560827320141e-5 3.929577862378673e-5 1.7980287516336745e-5 7321/7706/7323/7316/3093/7322/7128/54941/83737/9246/51191/6233/7311/55593/7318/5300/9641/1540/7314 19 Avian_infectious_bronchitis_virus R-HSA-176187 Activation of ATR in response to replication stress 20/2292 37/10654 1.4322576638680007e-5 4.531513558841275e-5 2.0734521499676767e-5 1017/6118/5883/5982/63967/545/993/84515/6119/3364/144715/5985/995/84126/1111/5984/5983/6117/5884/5810 20 Avian_infectious_bronchitis_virus R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 13/2292 19/10654 1.4831532827593905e-5 4.681422210036749e-5 2.1420447760481096e-5 7027/7153/4149/5934/1869/1875/993/5933/5111/4609/5928/1874/3065 13 Avian_infectious_bronchitis_virus R-HSA-5663220 RHO GTPases Activate Formins 52/2292 140/10654 1.5628726790972203e-5 4.9213863086465664e-5 2.2518434271426918e-5 5905/11130/5903/1783/1058/991/1856/51807/9212/347688/7277/10381/6232/332/1780/1781/5501/8655/81624/6714/79902/3796/5519/1062/699/7846/51143/998/11004/5527/1855/701/1857/7514/9184/5518/10383/5347/387/60/84790/84643/6396/9793/10726/81930/55746/140735/7280/5515/1778/5516 52 Avian_infectious_bronchitis_virus R-HSA-5675221 Negative regulation of MAPK pathway 21/2292 40/10654 1.592134327292703e-5 5.001705009325189e-5 2.2885942788045558e-5 4893/1844/8844/5594/7316/8315/5519/5894/6233/5527/7311/5518/1843/3845/3265/369/7529/7314/5595/5515/5516 21 Avian_infectious_bronchitis_virus R-HSA-3371571 HSF1-dependent transactivation 15/2292 24/10654 1.6585480836540382e-5 5.1980848174757154e-5 2.3784503787880825e-5 818/3303/1410/3337/3305/1387/3320/2033/3326/2475/3306/3304/3312/2288/10728 15 Avian_infectious_bronchitis_virus R-HSA-72766 Translation 93/2292 291/10654 1.7439270895206237e-5 5.45284244892364e-5 2.4950180005743543e-5 6158/6138/6144/5464/6203/9349/4736/6194/6191/6128/51121/6132/1938/6147/56945/8666/6129/1915/6217/6230/6222/1983/6152/6136/79590/8668/64432/8667/6125/51065/6154/8662/6141/10480/26986/6202/6232/2935/6160/55699/6155/63931/8661/6175/6218/9669/6209/6231/6229/11224/6205/6130/6142/6204/64969/54148/23107/8894/7965/1981/140801/23438/6156/6143/6181/6124/28973/6207/64978/51116/6233/1975/28957/64975/7311/6223/3646/51386/6730/6188/6189/8665/6135/6201/9045/51649/6187/64965/6168/6208/6137/6122/55037 93 Avian_infectious_bronchitis_virus R-HSA-186797 Signaling by PDGF 27/2292 58/10654 1.8539059874164007e-5 5.783144672690037e-5 2.646152019509666e-5 5295/4893/5290/5335/5340/4690/5782/5921/6778/6696/6776/6774/6772/6714/1281/5159/6654/2885/1398/5296/3845/6777/3265/1399/5781/7057/5156 27 Avian_infectious_bronchitis_virus R-HSA-8941326 RUNX2 regulates bone development 18/2292 32/10654 1.862036532235456e-5 5.794936123686045e-5 2.6515473491498504e-5 25/8841/23462/5594/4086/5925/10013/865/4094/9759/10413/6714/4089/25937/367/860/4091/5595 18 Avian_infectious_bronchitis_virus R-HSA-9034015 Signaling by NTRK3 (TRKC) 12/2292 17/10654 1.982313814595904e-5 6.154876459304765e-5 2.8162426663011375e-5 5295/4893/6464/5290/3667/5335/6714/6654/2885/581/3845/3265 12 Avian_infectious_bronchitis_virus R-HSA-198753 ERK/MAPK targets 14/2292 22/10654 2.3872263859099434e-5 7.34361557975068e-5 3.360165497609961e-5 5594/5519/5598/1432/4208/6195/6196/5518/6197/5600/51231/5595/5515/5516 14 Avian_infectious_bronchitis_virus R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 14/2292 22/10654 2.3872263859099434e-5 7.34361557975068e-5 3.360165497609961e-5 4000/3725/351/2309/10018/7531/823/2801/993/995/6648/8851/5052/1020 14 Avian_infectious_bronchitis_virus R-HSA-8863678 Neurodegenerative Diseases 14/2292 22/10654 2.3872263859099434e-5 7.34361557975068e-5 3.360165497609961e-5 4000/3725/351/2309/10018/7531/823/2801/993/995/6648/8851/5052/1020 14 Avian_infectious_bronchitis_virus R-HSA-9613829 Chaperone Mediated Autophagy 14/2292 22/10654 2.3872263859099434e-5 7.34361557975068e-5 3.360165497609961e-5 1915/1080/10013/7316/3043/10226/3320/6233/3326/7311/7431/3312/11315/7314 14 Avian_infectious_bronchitis_virus R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 11/2292 15/10654 2.557102997765746e-5 7.848067265032198e-5 3.590983836299702e-5 7316/4233/867/9146/6455/30011/6233/2885/7311/10254/7314 11 Avian_infectious_bronchitis_virus R-HSA-2142753 Arachidonic acid metabolism 27/2292 59/10654 2.723200344794437e-5 8.338627262680896e-5 3.815445855138485e-5 5730/5321/242/113612/1558/3248/246/1559/1543/5743/11283/1573/4051/5740/8529/2877/9536/239/80142/27306/247/6916/240/1579/5742/1557/10728 27 Avian_infectious_bronchitis_virus R-HSA-4090294 SUMOylation of intracellular receptors 17/2292 30/10654 2.7966585581061247e-5 8.511607019594428e-5 3.894594961549846e-5 7068/5241/5468/51588/6613/9759/8856/2099/7341/10401/2908/7329/367/6612/9063/7421/8554 17 Avian_infectious_bronchitis_virus R-HSA-4570464 SUMOylation of RNA binding proteins 23/2292 47/10654 2.8180320537846416e-5 8.511607019594428e-5 3.894594961549846e-5 1912/5903/7175/9631/8535/6045/80012/6613/3190/1911/4927/79902/7341/84733/57332/7329/9972/8021/6396/648/55746/8480/6015 23 Avian_infectious_bronchitis_virus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 23/2292 47/10654 2.8180320537846416e-5 8.511607019594428e-5 3.894594961549846e-5 818/4893/8844/7094/5594/409/5908/7414/8315/6714/3717/2335/408/1445/5894/8826/60/3845/3265/369/5245/7529/5595 23 Avian_infectious_bronchitis_virus R-HSA-6802949 Signaling by RAS mutants 23/2292 47/10654 2.8180320537846416e-5 8.511607019594428e-5 3.894594961549846e-5 818/4893/8844/7094/5594/409/5908/7414/8315/6714/3717/2335/408/1445/5894/8826/60/3845/3265/369/5245/7529/5595 23 Avian_infectious_bronchitis_virus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 23/2292 47/10654 2.8180320537846416e-5 8.511607019594428e-5 3.894594961549846e-5 818/4893/8844/7094/5594/409/5908/7414/8315/6714/3717/2335/408/1445/5894/8826/60/3845/3265/369/5245/7529/5595 23 Avian_infectious_bronchitis_virus R-HSA-9649948 Signaling downstream of RAS mutants 23/2292 47/10654 2.8180320537846416e-5 8.511607019594428e-5 3.894594961549846e-5 818/4893/8844/7094/5594/409/5908/7414/8315/6714/3717/2335/408/1445/5894/8826/60/3845/3265/369/5245/7529/5595 23 Avian_infectious_bronchitis_virus R-HSA-209543 p75NTR recruits signalling complexes 10/2292 13/10654 3.1249503453540865e-5 9.41727117649693e-5 4.308993212574461e-5 4804/8878/4615/7316/3654/7189/6233/7311/3551/7314 10 Avian_infectious_bronchitis_virus R-HSA-389356 CD28 co-stimulation 18/2292 33/10654 3.275302422558233e-5 9.8259072676747e-5 4.495969897252767e-5 5295/5290/207/941/57761/6714/4067/10000/2534/998/942/208/2885/2475/7409/3932/5296/940 18 Avian_infectious_bronchitis_virus R-HSA-5693568 Resolution of D-loop Structures through Holliday Junction Intermediates 18/2292 33/10654 3.275302422558233e-5 9.8259072676747e-5 4.495969897252767e-5 80010/83990/5888/9156/1763/7486/10111/675/472/580/116028/641/10524/4683/79728/672/5932/7156 18 Avian_infectious_bronchitis_virus R-HSA-1296041 Activation of G protein gated Potassium channels 15/2292 25/10654 3.3219623821284554e-5 9.876906011149783e-5 4.519305026438852e-5 2788/54331/2550/94235/55970/9568/2792/2793/2785/2783/2784/2782/2786/2790/2787 15 Avian_infectious_bronchitis_virus R-HSA-1296059 G protein gated Potassium channels 15/2292 25/10654 3.3219623821284554e-5 9.876906011149783e-5 4.519305026438852e-5 2788/54331/2550/94235/55970/9568/2792/2793/2785/2783/2784/2782/2786/2790/2787 15 Avian_infectious_bronchitis_virus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 15/2292 25/10654 3.3219623821284554e-5 9.876906011149783e-5 4.519305026438852e-5 5594/5519/5598/1432/4208/6195/1385/6196/5518/6197/5600/51231/5595/5515/5516 15 Avian_infectious_bronchitis_virus R-HSA-997272 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits 15/2292 25/10654 3.3219623821284554e-5 9.876906011149783e-5 4.519305026438852e-5 2788/54331/2550/94235/55970/9568/2792/2793/2785/2783/2784/2782/2786/2790/2787 15 Avian_infectious_bronchitis_virus R-HSA-1181150 Signaling by NODAL 13/2292 20/10654 3.401321252632168e-5 1.0067910907791217e-4 4.606701766722866e-5 2309/55997/6997/130399/4838/91/93/4089/92/4088/4087/8928/10589 13 Avian_infectious_bronchitis_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 13/2292 20/10654 3.401321252632168e-5 1.0067910907791217e-4 4.606701766722866e-5 1147/7321/7098/7323/7316/7335/7322/7189/6233/7311/7334/3551/7314 13 Avian_infectious_bronchitis_virus R-HSA-4755510 SUMOylation of immune response proteins 9/2292 11/10654 3.4937001421333104e-5 1.0272866643093973e-4 4.700481892169599e-5 51588/10210/5970/4792/7341/10401/7329/6612/9641 9 Avian_infectious_bronchitis_virus R-HSA-5655291 Signaling by FGFR4 in disease 9/2292 11/10654 3.4937001421333104e-5 1.0272866643093973e-4 4.700481892169599e-5 5295/4893/5290/5335/2264/6654/2885/3845/3265 9 Avian_infectious_bronchitis_virus R-HSA-8851805 MET activates RAS signaling 9/2292 11/10654 3.4937001421333104e-5 1.0272866643093973e-4 4.700481892169599e-5 4893/6464/10048/3082/4233/6654/2885/3845/3265 9 Avian_infectious_bronchitis_virus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 19/2292 36/10654 3.664809735239827e-5 1.0752261161540638e-4 4.919835002791236e-5 4893/8844/7094/5594/409/5908/7414/6714/2335/408/1445/5894/8826/60/3845/3265/369/7529/5595 19 Avian_infectious_bronchitis_virus R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 16/2292 28/10654 4.197193307609699e-5 1.2260222556438857e-4 5.6098220801154565e-5 10694/10575/7277/10381/7203/10576/908/6950/7846/10574/10383/60/84790/22948/10693/7280 16 Avian_infectious_bronchitis_virus R-HSA-69205 G1/S-Specific Transcription 16/2292 28/10654 4.197193307609699e-5 1.2260222556438857e-4 5.6098220801154565e-5 7027/898/5934/5422/1869/1875/983/5933/5111/5928/1874/3065/8900/1719/7083/6241 16 Avian_infectious_bronchitis_virus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 35/2292 86/10654 4.287852655703839e-5 1.2497636186865457e-4 5.7184537317805436e-5 5295/25/5290/5335/5747/4690/5336/4627/4771/5594/2268/3708/8398/3055/6850/3709/4641/6714/4067/3320/2534/998/695/2885/1398/7410/3326/5580/7409/9844/3710/60/5296/10787/5595 35 Avian_infectious_bronchitis_virus R-HSA-8854518 AURKA Activation by TPX2 31/2292 73/10654 4.38604902136875e-5 1.2755932961709988e-4 5.836640734020929e-5 115106/22995/11258/22981/7531/203068/54801/7532/1454/22974/7277/1781/8655/983/1639/6790/10121/7846/7283/3320/10540/54930/5518/10383/55835/5347/9662/1453/9793/8481/1778 31 Avian_infectious_bronchitis_virus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 14/2292 23/10654 4.892761939518685e-5 1.4198603275465986e-4 6.496753039746174e-5 5601/6885/7316/7335/5602/10454/3654/7189/5609/6233/7311/5599/7334/7314 14 Avian_infectious_bronchitis_virus R-HSA-5693537 Resolution of D-Loop Structures 18/2292 34/10654 5.56607955486274e-5 1.6117430363211239e-4 7.374736984589306e-5 80010/83990/5888/9156/1763/7486/10111/675/472/580/116028/641/10524/4683/79728/672/5932/7156 18 Avian_infectious_bronchitis_virus R-HSA-4551638 SUMOylation of chromatin organization proteins 30/2292 71/10654 6.488681599489526e-5 1.8748208005466485e-4 8.578483037114822e-5 1912/5903/7175/9631/8535/6045/80012/6613/9759/1911/4927/79902/7341/84733/23512/57332/3066/3065/1107/7329/9972/6612/9063/8021/6396/648/55746/8480/6015/8554 30 Avian_infectious_bronchitis_virus R-HSA-446203 Asparagine N-linked glycosylation 94/2292 304/10654 6.548965702117241e-5 1.888143358272763e-4 8.639442108739764e-5 2348/84364/6811/23256/22820/6711/7841/11014/11258/6712/1783/5700/4253/51014/79139/51807/286/2801/93661/347688/5861/55860/830/7277/10381/9945/10671/1780/1604/9554/377/84447/1781/7316/9570/22872/966/8655/1315/11196/84516/1639/832/57731/81562/10282/10121/7415/55738/8615/6710/81876/11316/11015/7846/8729/23423/10972/51226/51143/1314/3630/10540/381/6708/6233/9276/287/6709/51332/7311/9871/10383/84790/378/10945/6396/375/26286/1453/288/26958/10610/140735/7280/10959/10652/54732/829/7314/51164/1778/22818/372 94 Avian_infectious_bronchitis_virus R-HSA-1433559 Regulation of KIT signaling 11/2292 16/10654 6.586136221448966e-5 1.8906753118469875e-4 8.651027387066587e-5 5777/3815/9306/6714/8651/867/4067/2534/6654/2885/3932 11 Avian_infectious_bronchitis_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 11/2292 16/10654 6.586136221448966e-5 1.8906753118469875e-4 8.651027387066587e-5 8454/1147/8945/4790/6500/7316/23291/6233/7311/3551/7314 11 Avian_infectious_bronchitis_virus R-HSA-5218921 VEGFR2 mediated cell proliferation 13/2292 21/10654 7.16902235012296e-5 2.0491711953570348e-4 9.376245630723275e-5 5590/4893/5335/7422/3708/5921/3709/6714/5580/3791/3710/3845/3265 13 Avian_infectious_bronchitis_virus R-HSA-6807004 Negative regulation of MET activity 13/2292 21/10654 7.16902235012296e-5 2.0491711953570348e-4 9.376245630723275e-5 3082/7316/4233/867/9146/6455/5771/30011/6233/2885/7311/10254/7314 13 Avian_infectious_bronchitis_virus R-HSA-416476 G alpha (q) signalling events 71/2292 217/10654 7.349807305685772e-5 2.0963476083883187e-4 9.592107359387045e-5 5295/2788/10316/2149/351/4893/5290/54331/59345/23566/2358/6863/1131/84539/5594/846/10681/51764/94235/3708/301/2769/3827/56923/55970/5020/4314/3709/2792/2840/1906/5367/5598/2793/2785/6195/2783/624/2784/2829/2782/8525/6288/185/695/2786/6654/2885/183/5580/1385/6196/2847/57121/9170/5731/3710/1956/5296/10874/6197/3845/3265/9630/1902/129521/2791/5595/2790/2787/623 71 Avian_infectious_bronchitis_virus R-HSA-2500257 Resolution of Sister Chromatid Cohesion 46/2292 126/10654 7.719337792727418e-5 2.1970422948531883e-4 1.0052848812391309e-4 5905/11130/5903/1783/1058/991/51807/9212/347688/7277/10381/6232/332/1780/1781/891/5501/8655/983/79902/3796/5519/1062/699/7846/51143/11004/5527/701/7514/9184/5518/10383/5347/84790/84643/6396/9793/10726/81930/55746/140735/7280/5515/1778/5516 46 Avian_infectious_bronchitis_virus R-HSA-71291 Metabolism of amino acids and derivatives 111/2292 372/10654 7.923412675301701e-5 2.2503167768660697e-4 1.029661303781772e-4 6158/5718/5689/6138/6144/6203/5684/27165/9349/4736/1728/5720/1629/6194/6191/6128/5682/51121/6132/6147/6129/3620/5160/6217/5700/122706/5707/6230/6222/1743/383/6152/5690/6136/6125/5717/9491/23198/51065/6154/6141/143471/6202/5706/5705/10197/6232/6160/6155/10213/5709/6175/6218/5695/6209/5714/6231/6229/11224/6205/9861/6130/5715/6142/5711/6204/5701/5688/5687/23474/5685/5683/5698/5708/7965/8604/5692/5686/5713/140801/6156/5699/6143/5710/6181/6124/5702/6207/5719/5704/6233/5716/7311/6223/6188/6189/6135/6201/6303/5694/9045/6187/6168/5693/6208/5721/6137/5696/5691/6122/7296 111 Avian_infectious_bronchitis_virus R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 17/2292 32/10654 8.460590504546879e-5 2.3876073203509413e-4 1.0924803528395726e-4 10694/51807/10575/7277/10381/7203/10576/908/6950/7846/10574/10383/60/84790/22948/10693/7280 17 Avian_infectious_bronchitis_virus R-HSA-451326 Activation of kainate receptors upon glutamate binding 17/2292 32/10654 8.460590504546879e-5 2.3876073203509413e-4 1.0924803528395726e-4 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Avian_infectious_bronchitis_virus R-HSA-5673000 RAF activation 17/2292 32/10654 8.460590504546879e-5 2.3876073203509413e-4 1.0924803528395726e-4 818/4893/8844/8315/6714/5519/3717/5894/5527/5518/3845/3265/369/5245/7529/5515/5516 17 Avian_infectious_bronchitis_virus R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 10/2292 14/10654 8.818406600857427e-5 2.467671763097078e-4 1.1291148655233194e-4 2801/5594/5861/891/983/8548/8615/81876/5347/5595 10 Avian_infectious_bronchitis_virus R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 10/2292 14/10654 8.818406600857427e-5 2.467671763097078e-4 1.1291148655233194e-4 6118/4436/9156/2956/4292/5111/5395/6119/6117/10714 10 Avian_infectious_bronchitis_virus R-HSA-877312 Regulation of IFNG signaling 10/2292 14/10654 8.818406600857427e-5 2.467671763097078e-4 1.1291148655233194e-4 5777/9021/6772/8651/7341/3717/5771/3458/5781/8554 10 Avian_infectious_bronchitis_virus R-HSA-9027284 Erythropoietin activates RAS 10/2292 14/10654 8.818406600857427e-5 2.467671763097078e-4 1.1291148655233194e-4 4893/6464/4067/3717/6654/2885/7409/3845/3265/1399 10 Avian_infectious_bronchitis_virus R-HSA-73887 Death Receptor Signalling 50/2292 141/10654 9.11264447589081e-5 2.5446629857204525e-4 1.1643431869228245e-4 7124/1147/4804/8841/4790/6885/10018/7531/29/8793/55072/27237/8878/1894/355/841/27005/4615/7316/9828/5970/4792/8797/7128/843/836/23365/10616/8837/11108/10454/3066/3065/3654/7189/6654/6233/7410/7409/7311/26574/387/331/5599/1540/3551/8795/5663/7314/10672 50 Avian_infectious_bronchitis_virus R-HSA-452723 Transcriptional regulation of pluripotent stem cells 14/2292 24/10654 9.420661337729145e-5 2.603386079223075e-4 1.1912126915364e-4 7547/6997/6657/27086/5460/2041/6774/57167/4089/9314/79923/2247/4087/2034 14 Avian_infectious_bronchitis_virus R-HSA-5260271 Diseases of Immune System 14/2292 24/10654 9.420661337729145e-5 2.603386079223075e-4 1.1912126915364e-4 1147/81793/4790/10333/7099/4615/7098/7100/5970/4792/7096/695/7097/3551 14 Avian_infectious_bronchitis_virus R-HSA-5602358 Diseases associated with the TLR signaling cascade 14/2292 24/10654 9.420661337729145e-5 2.603386079223075e-4 1.1912126915364e-4 1147/81793/4790/10333/7099/4615/7098/7100/5970/4792/7096/695/7097/3551 14 Avian_infectious_bronchitis_virus R-HSA-8940973 RUNX2 regulates osteoblast differentiation 14/2292 24/10654 9.420661337729145e-5 2.603386079223075e-4 1.1912126915364e-4 25/8841/23462/5594/5925/10013/865/4094/10413/6714/25937/367/860/5595 14 Avian_infectious_bronchitis_virus R-HSA-982772 Growth hormone receptor signaling 14/2292 24/10654 9.420661337729145e-5 2.603386079223075e-4 1.1912126915364e-4 5777/3667/9021/5594/6776/6774/6772/8651/4067/3717/1154/8835/6777/5595 14 Avian_infectious_bronchitis_virus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 19/2292 38/10654 9.628036621804374e-5 2.648207616862638e-4 1.2117213609637012e-4 5903/7175/9631/51588/4927/79902/7341/7428/7329/5987/5371/9972/9063/8021/6396/55746/8480/4193/8554 19 Avian_infectious_bronchitis_virus R-HSA-5689896 Ovarian tumor domain proteases 19/2292 38/10654 9.628036621804374e-5 2.648207616862638e-4 1.2117213609637012e-4 7321/55611/7706/7316/80124/983/2099/79589/7415/7128/5728/7157/7189/6233/7311/55593/78990/387/7314 19 Avian_infectious_bronchitis_virus R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 40/2292 106/10654 9.642497704041888e-5 2.648207616862638e-4 1.2117213609637012e-4 9318/7018/1856/4738/1212/2069/1601/29988/409/1080/29978/58513/338/7316/1950/64708/10980/22848/7037/867/1129/9146/6455/10920/408/10987/185/30011/6233/2885/2873/7311/1213/1956/1211/8533/10254/50813/7314/51138 40 Avian_infectious_bronchitis_virus R-HSA-451927 Interleukin-2 family signaling 21/2292 44/10654 9.923107954481067e-5 2.719666624561478e-4 1.244418346468386e-4 5295/5777/3635/6464/5290/1437/3578/6776/6774/6850/6772/3567/3558/3717/6654/2885/3932/5293/5296/6777/3600 21 Avian_infectious_bronchitis_virus R-HSA-212165 Epigenetic regulation of gene expression 52/2292 149/10654 1.0699250001553159e-4 2.9263657088436976e-4 1.338996163600839e-4 8467/23451/5252/902/9015/10514/79595/2648/2074/2146/29128/1788/9112/9219/1786/6839/9014/5931/51082/8819/6996/4331/9013/23309/4641/1108/8850/5928/2932/29947/57459/2965/54815/2033/23512/2068/3066/3065/2071/1107/2968/57504/22823/6908/23411/60/25942/8726/10284/53615/1022/10919 52 Avian_infectious_bronchitis_virus R-HSA-2424491 DAP12 signaling 16/2292 30/10654 1.2871954858308647e-4 3.5134106293580156e-4 1.6076060964108514e-4 5295/4893/6464/5290/5335/5336/6850/2534/695/6654/2885/7410/3932/5296/3845/3265 16 Avian_infectious_bronchitis_virus R-HSA-9018519 Estrogen-dependent gene expression 52/2292 150/10654 1.3006747454022527e-4 3.539321101686477e-4 1.619461765352039e-4 3727/27161/3725/3838/596/5241/4435/5430/2625/57690/27327/51523/192670/200845/865/5469/1655/6667/2099/4609/7391/8850/10524/1387/3320/2033/595/4602/8312/192669/3065/2066/861/23028/23112/10498/3326/1025/2353/10499/1386/6908/4343/904/3276/26523/8202/8648/2288/10728/7528/6387 52 Avian_infectious_bronchitis_virus R-HSA-380259 Loss of Nlp from mitotic centrosomes 29/2292 70/10654 1.3046596553513965e-4 3.539321101686477e-4 1.619461765352039e-4 115106/22995/11258/22981/7531/203068/54801/7532/1454/7277/1781/8655/983/1639/10121/7846/7283/3320/10540/54930/5518/10383/55835/5347/9662/1453/9793/8481/1778 29 Avian_infectious_bronchitis_virus R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 29/2292 70/10654 1.3046596553513965e-4 3.539321101686477e-4 1.619461765352039e-4 115106/22995/11258/22981/7531/203068/54801/7532/1454/7277/1781/8655/983/1639/10121/7846/7283/3320/10540/54930/5518/10383/55835/5347/9662/1453/9793/8481/1778 29 Avian_infectious_bronchitis_virus R-HSA-420092 Glucagon-type ligand receptors 17/2292 33/10654 1.3969959091659828e-4 3.782110876034734e-4 1.7305533406228158e-4 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Avian_infectious_bronchitis_virus R-HSA-1250196 SHC1 events in ERBB2 signaling 13/2292 22/10654 1.4076060965097413e-4 3.7954075314797073e-4 1.7366373958643518e-4 4893/6464/5782/2069/2064/1950/2066/6654/2885/5580/1956/3845/3265 13 Avian_infectious_bronchitis_virus R-HSA-389357 CD28 dependent PI3K/Akt signaling 13/2292 22/10654 1.4076060965097413e-4 3.7954075314797073e-4 1.7366373958643518e-4 5295/5290/207/941/57761/10000/2534/942/208/2475/3932/5296/940 13 Avian_infectious_bronchitis_virus R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 36/2292 94/10654 1.4952068596075732e-4 4.0234657313076516e-4 1.8409883502664218e-4 10844/115106/22995/11258/22981/7531/203068/54801/51807/7532/1454/347688/7277/10381/1781/8655/983/1639/10121/7846/7283/3320/80097/10540/54930/5518/10383/55835/5347/84790/9662/1453/9793/8481/7280/1778 36 Avian_infectious_bronchitis_virus R-HSA-432142 Platelet sensitization by LDL 11/2292 17/10654 1.5026477300679526e-4 4.035336242843776e-4 1.8464198550707654e-4 5777/5321/2268/338/5519/1432/5527/5518/5781/5515/5516 11 Avian_infectious_bronchitis_virus R-HSA-913531 Interferon Signaling 65/2292 199/10654 1.5381260209953868e-4 4.122301529106348e-4 1.8862119372155652e-4 80263/3665/818/5777/3837/3838/5903/6737/5335/7175/960/9631/7412/2316/9021/54739/3383/55223/1982/7706/3662/9470/7316/2317/4734/6672/6772/8651/4927/3659/79902/6041/3840/1958/7341/6059/3717/1981/5771/3458/3454/7324/9246/5371/51191/6233/5580/7311/81603/9972/7318/5610/5300/8021/6396/7334/3456/7297/5781/55746/5696/8480/7314/5595/8554 65 Avian_infectious_bronchitis_virus R-HSA-6802957 Oncogenic MAPK signaling 29/2292 71/10654 1.75746806884355e-4 4.7006977263044344e-4 2.15086453574385e-4 4000/818/8805/4893/10018/8844/7094/5594/409/5908/7414/10533/8315/6714/3717/2335/408/1445/5894/56829/8826/60/3845/3265/369/4763/5245/7529/5595 29 Avian_infectious_bronchitis_virus R-HSA-418346 Platelet homeostasis 34/2292 88/10654 1.8527627677206472e-4 4.945651315839484e-4 2.2629461924064017e-4 2788/5777/5321/54331/59345/2268/10681/51764/94235/3708/338/55970/3709/2792/5519/1432/2793/5136/4843/2785/4846/2783/2784/2782/2786/5527/5518/3710/5781/2791/2790/5515/2787/5516 34 Avian_infectious_bronchitis_virus R-HSA-167044 Signalling to RAS 12/2292 20/10654 2.0974011371367813e-4 5.557137242970943e-4 2.542739421274045e-4 4893/6464/6714/1432/4914/5603/6654/2885/3845/5600/3265/6300 12 Avian_infectious_bronchitis_virus R-HSA-69186 Lagging Strand Synthesis 12/2292 20/10654 2.0974011371367813e-4 5.557137242970943e-4 2.542739421274045e-4 6118/1763/5982/5422/5111/6119/5985/5984/5983/6117/5981/10714 12 Avian_infectious_bronchitis_virus R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 12/2292 20/10654 2.0974011371367813e-4 5.557137242970943e-4 2.542739421274045e-4 2648/23462/22938/8850/1387/4088/59/2033/4855/9794/3516/4851 12 Avian_infectious_bronchitis_virus R-HSA-9012852 Signaling by NOTCH3 22/2292 49/10654 2.0985285534642526e-4 5.557137242970943e-4 2.542739421274045e-4 142678/2648/23462/4904/7316/1950/4854/6772/11060/22938/8850/1387/26508/2033/9794/6233/7311/1956/3516/4851/5663/7314 22 Avian_infectious_bronchitis_virus R-HSA-182971 EGFR downregulation 16/2292 31/10654 2.1316590753297677e-4 5.61783209307872e-4 2.5705111284120264e-4 5782/2069/58513/7316/1950/867/9146/6455/998/30011/6233/2885/7311/1956/10254/7314 16 Avian_infectious_bronchitis_virus R-HSA-2162123 Synthesis of Prostaglandins (PG) and Thromboxanes (TX) 10/2292 15/10654 0.00021341013807040781 5.61783209307872e-4 2.5705111284120264e-4 5730/3248/5743/5740/9536/80142/27306/6916/5742/10728 10 Avian_infectious_bronchitis_virus R-HSA-5358508 Mismatch Repair 10/2292 15/10654 0.00021341013807040781 5.61783209307872e-4 2.5705111284120264e-4 6118/4436/9156/2956/4292/5111/5395/6119/6117/10714 10 Avian_infectious_bronchitis_virus R-HSA-187687 Signalling to ERKs 17/2292 34/10654 2.2373838628456937e-4 5.878097249133066e-4 2.6895987887213884e-4 4893/6464/5594/6714/1432/4914/5603/6654/2885/1398/3845/5600/3265/1399/6300/7529/5595 17 Avian_infectious_bronchitis_virus R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 32/2292 82/10654 2.286103210312749e-4 5.962271887821843e-4 2.7281139742759976e-4 10844/115106/22995/11258/22981/7531/203068/54801/7532/1454/7277/1781/728642/8655/983/1639/10121/7846/7283/3320/80097/10540/54930/5518/10383/55835/5347/9662/1453/9793/8481/1778 32 Avian_infectious_bronchitis_virus R-HSA-380287 Centrosome maturation 32/2292 82/10654 2.286103210312749e-4 5.962271887821843e-4 2.7281139742759976e-4 10844/115106/22995/11258/22981/7531/203068/54801/7532/1454/7277/1781/728642/8655/983/1639/10121/7846/7283/3320/80097/10540/54930/5518/10383/55835/5347/9662/1453/9793/8481/1778 32 Avian_infectious_bronchitis_virus R-HSA-165159 mTOR signalling 19/2292 40/10654 2.287328029036758e-4 5.962271887821843e-4 2.7281139742759976e-4 5563/6194/207/51422/7249/53632/6198/5571/6794/1981/5494/208/10542/1975/2475/5562/5564/5565/7529 19 Avian_infectious_bronchitis_virus R-HSA-5674135 MAP2K and MAPK activation 19/2292 40/10654 2.287328029036758e-4 5.962271887821843e-4 2.7281139742759976e-4 4893/8844/7094/5594/409/5908/7414/6714/2335/408/1445/5894/8826/60/3845/3265/369/7529/5595 19 Avian_infectious_bronchitis_virus R-HSA-141424 Amplification of signal from the kinetochores 36/2292 96/10654 2.4395874259787456e-4 6.334367351664112e-4 2.8983710262474484e-4 5905/11130/5903/1783/1058/991/9212/6232/332/1780/1781/5501/8655/79902/3796/5519/1062/699/51143/11004/5527/701/7514/9184/5518/5347/84643/6396/9793/10726/81930/55746/140735/5515/1778/5516 36 Avian_infectious_bronchitis_virus R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 36/2292 96/10654 2.4395874259787456e-4 6.334367351664112e-4 2.8983710262474484e-4 5905/11130/5903/1783/1058/991/9212/6232/332/1780/1781/5501/8655/79902/3796/5519/1062/699/51143/11004/5527/701/7514/9184/5518/5347/84643/6396/9793/10726/81930/55746/140735/5515/1778/5516 36 Avian_infectious_bronchitis_virus R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission 66/2292 206/10654 2.5647175602277333e-4 6.646310875920897e-4 3.0411047867537534e-4 2788/818/5563/3838/8573/4893/54331/23426/2904/59345/2770/51807/2550/4646/5594/347688/51422/10681/51764/112/7277/94235/114/53632/10381/108/113/55970/111/107/9568/2792/346562/6714/5571/2793/2567/7846/2785/6195/2783/2784/2782/2066/2786/2771/1385/6196/5562/10383/84790/6197/3845/196883/115/3265/5564/5565/2791/7280/109/2773/5595/4193/2790/2787 66 Avian_infectious_bronchitis_virus R-HSA-195258 RHO GTPase Effectors 97/2292 327/10654 2.7613713173405745e-4 7.142032222713874e-4 3.2679284470928826e-4 3831/5905/11130/25/5590/5903/64837/4638/1499/7531/5747/4690/1783/1058/4659/991/1856/4627/51807/2316/7532/10971/4771/9212/5594/347688/3798/1027/1080/7533/2810/7277/10381/6232/7534/332/1780/1781/5501/10398/8655/5289/81624/6279/6714/79902/3796/5519/1432/2017/1062/699/7846/999/89953/995/51143/998/23028/695/11004/5527/1855/2885/5580/701/1857/7514/9184/367/8826/147700/10499/5518/3799/10383/5347/387/60/5300/84790/84643/6396/5600/9793/10726/81930/55746/140735/7280/7529/10787/4221/5595/5515/1778/5516 97 Avian_infectious_bronchitis_virus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 9/2292 13/10654 2.9661992839795885e-4 7.642122720040255e-4 3.496751268297225e-4 207/10193/2064/7316/10000/208/6233/7311/7314 9 Avian_infectious_bronchitis_virus R-HSA-2892247 POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation 9/2292 13/10654 2.9661992839795885e-4 7.642122720040255e-4 3.496751268297225e-4 7547/6997/6657/5460/2041/6774/57167/79923/2247 9 Avian_infectious_bronchitis_virus R-HSA-5654736 Signaling by FGFR1 22/2292 50/10654 2.993569182950318e-4 7.697749327586532e-4 3.5222039360459953e-4 5295/4893/6464/5290/5335/5594/7316/6714/867/2247/6654/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 22 Avian_infectious_bronchitis_virus R-HSA-437239 Recycling pathway of L1 21/2292 47/10654 3.157276025633561e-4 8.103066794111567e-4 3.7076621414498166e-4 7430/51807/5594/347688/7277/10381/8650/285643/6714/7846/6195/6196/1759/1213/10383/24137/1211/60/84790/6197/7280 21 Avian_infectious_bronchitis_virus R-HSA-9619483 Activation of AMPK downstream of NMDARs 15/2292 29/10654 3.257239661245079e-4 8.343544670727778e-4 3.817695878260933e-4 5563/51807/347688/51422/7277/53632/10381/5571/7846/5562/10383/84790/5564/5565/7280 15 Avian_infectious_bronchitis_virus R-HSA-388841 Costimulation by the CD28 family 28/2292 70/10654 3.421498987684014e-4 8.747479177725733e-4 4.002521292795322e-4 5295/5777/5290/207/941/57761/6714/5519/29126/4067/10000/2534/1445/998/942/208/5527/2885/2475/7409/3932/5518/5296/5781/1493/940/5515/5516 28 Avian_infectious_bronchitis_virus R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 18/2292 38/10654 3.476939149706268e-4 8.872189554422891e-4 4.0595841251863876e-4 6627/27250/5908/1265/3313/6175/3185/6950/3458/3181/998/6648/302/4282/375/5721/3586/829 18 Avian_infectious_bronchitis_virus R-HSA-112043 PLC beta mediated events 23/2292 54/10654 3.9187505291930926e-4 9.980450678556787e-4 4.5666832170731625e-4 818/3838/5321/2770/5594/112/114/3708/108/113/111/107/3709/346562/5136/2771/5580/1385/3710/196883/115/109/2773 23 Avian_infectious_bronchitis_virus R-HSA-1059683 Interleukin-6 signaling 8/2292 11/10654 3.9823860452681693e-4 0.0010046473886926519 4.5968929828753394e-4 9021/6774/6772/867/3717/7297/5781/3569 8 Avian_infectious_bronchitis_virus R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 8/2292 11/10654 3.9823860452681693e-4 0.0010046473886926519 4.5968929828753394e-4 7422/3091/10370/1387/2033/2034/405/768 8 Avian_infectious_bronchitis_virus R-HSA-2586552 Signaling by Leptin 8/2292 11/10654 3.9823860452681693e-4 0.0010046473886926519 4.5968929828753394e-4 3667/9021/3952/6776/6774/3717/6777/5781 8 Avian_infectious_bronchitis_virus R-HSA-5625970 RHO GTPases activate KTN1 8/2292 11/10654 3.9823860452681693e-4 0.0010046473886926519 4.5968929828753394e-4 3831/64837/3798/89953/998/147700/3799/387 8 Avian_infectious_bronchitis_virus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 8/2292 11/10654 3.9823860452681693e-4 0.0010046473886926519 4.5968929828753394e-4 6885/7098/7316/10454/7189/6233/7311/7314 8 Avian_infectious_bronchitis_virus R-HSA-438064 Post NMDA receptor activation events 31/2292 81/10654 4.255861359207082e-4 0.0010716081910139572 4.903280722278183e-4 818/5563/3838/4893/2904/51807/5594/347688/51422/7277/114/53632/10381/107/6714/5571/7846/6195/2066/1385/6196/5562/10383/84790/6197/3845/3265/5564/5565/7280/5595 31 Avian_infectious_bronchitis_virus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 13/2292 24/10654 4.562507230635568e-4 0.001144493339210278 5.236776066087806e-4 6885/5606/7316/7335/1432/10454/3654/7189/6233/7311/5600/7334/7314 13 Avian_infectious_bronchitis_virus R-HSA-933542 TRAF6 mediated NF-kB activation 13/2292 24/10654 4.562507230635568e-4 0.001144493339210278 5.236776066087806e-4 1147/351/4790/4214/7706/5970/4792/4793/3146/6288/7189/6285/3551 13 Avian_infectious_bronchitis_virus R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 10/2292 16/10654 4.5932476449693797e-4 0.001145731435037306 5.242441132342344e-4 7027/5934/1869/1875/890/983/5933/5928/1874/3065 10 Avian_infectious_bronchitis_virus R-HSA-1963640 GRB2 events in ERBB2 signaling 10/2292 16/10654 4.5932476449693797e-4 0.001145731435037306 5.242441132342344e-4 4893/2069/2064/1950/2066/6654/2885/1956/3845/3265 10 Avian_infectious_bronchitis_virus R-HSA-429958 mRNA decay by 3' to 5' exoribonuclease 10/2292 16/10654 4.5932476449693797e-4 0.001145731435037306 5.242441132342344e-4 5393/23404/51013/11340/51010/56915/23016/54512/118460/22894 10 Avian_infectious_bronchitis_virus R-HSA-8856828 Clathrin-mediated endocytosis 49/2292 146/10654 4.7605695970101737e-4 0.0011852483557415984 5.423255871458713e-4 9318/7018/5868/1856/4738/1212/2069/1601/29988/409/1080/29978/382/58513/338/7316/1950/64708/26130/55738/10980/22848/7037/2017/867/1129/9146/6455/10920/408/10987/185/30011/6233/2885/2873/7311/1759/1213/2580/1956/1211/60/8533/3312/10254/50813/7314/51138 49 Avian_infectious_bronchitis_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 15/2292 30/10654 5.227283836659297e-4 0.001299019042990706 5.943828243177009e-4 7124/1147/6885/55072/27005/7316/7128/10616/10454/6233/7311/331/1540/3551/7314 15 Avian_infectious_bronchitis_virus R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 29/2292 75/10654 5.285114288846358e-4 0.0013109445498590965 5.998394929416919e-4 5295/5290/3667/3815/2069/3082/930/941/2064/1950/4233/6714/2099/5159/2247/2534/2264/2066/942/2885/7409/3932/5293/1956/118788/5296/5781/5156/940 29 Avian_infectious_bronchitis_virus R-HSA-2871809 FCERI mediated Ca+2 mobilization 16/2292 33/10654 5.318683280006119e-4 0.0013168189830795821 6.025274152071108e-4 6464/5335/4772/5336/3708/5530/6850/3709/4067/5534/695/6654/2885/7410/7409/3710 16 Avian_infectious_bronchitis_virus R-HSA-112040 G-protein mediated events 23/2292 55/10654 5.380222359440208e-4 0.0013295837073792872 6.083680785305889e-4 818/3838/5321/2770/5594/112/114/3708/108/113/111/107/3709/346562/5136/2771/5580/1385/3710/196883/115/109/2773 23 Avian_infectious_bronchitis_virus R-HSA-180336 SHC1 events in EGFR signaling 9/2292 14/10654 6.71804480698854e-4 0.0016479623725430452 7.540463202958932e-4 4893/6464/2069/1950/6654/2885/1956/3845/3265 9 Avian_infectious_bronchitis_virus R-HSA-419408 Lysosphingolipid and LPA receptors 9/2292 14/10654 6.71804480698854e-4 0.0016479623725430452 7.540463202958932e-4 9294/23566/1903/53637/1901/57121/9170/8698/1902 9 Avian_infectious_bronchitis_virus R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 9/2292 14/10654 6.71804480698854e-4 0.0016479623725430452 7.540463202958932e-4 6118/4436/9156/4292/5111/5395/6119/6117/10714 9 Avian_infectious_bronchitis_virus R-HSA-8941856 RUNX3 regulates NOTCH signaling 9/2292 14/10654 6.71804480698854e-4 0.0016479623725430452 7.540463202958932e-4 2648/864/22938/8850/1387/2033/9794/3516/4851 9 Avian_infectious_bronchitis_virus R-HSA-9612973 Autophagy 41/2292 119/10654 7.38783812464479e-4 0.0018089338937549377 8.277009044445305e-4 5563/1459/1915/8878/9821/51422/7249/1080/1460/10533/10013/53632/26100/7316/11152/8655/5289/1457/8678/6714/3043/10226/5571/3320/128866/55054/81631/10542/6233/3326/2475/7311/5562/7251/7431/3312/5564/11315/5565/140735/7314 41 Avian_infectious_bronchitis_virus R-HSA-937041 IKK complex recruitment mediated by RIP1 13/2292 25/10654 7.64377053260089e-4 0.0018681655687017222 8.548031170209399e-4 1147/7321/7099/7323/7316/7335/7322/7189/6233/7311/7334/3551/7314 13 Avian_infectious_bronchitis_virus R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 17/2292 37/10654 7.843770014540603e-4 0.0019135351024483671 8.755625290956256e-4 27161/8841/57690/27327/192670/348/9611/2874/9612/2033/192669/23028/23112/4343/1071/26523/8648 17 Avian_infectious_bronchitis_virus R-HSA-1296065 Inwardly rectifying K+ channels 15/2292 31/10654 8.129432050405732e-4 0.0019759860385292764 9.041377558941451e-4 2788/54331/2550/94235/55970/9568/2792/2793/2785/2783/2784/2782/2786/2790/2787 15 Avian_infectious_bronchitis_virus R-HSA-5654733 Negative regulation of FGFR4 signaling 15/2292 31/10654 8.129432050405732e-4 0.0019759860385292764 9.041377558941451e-4 5594/7316/6714/867/2247/2264/6233/2885/7311/5518/5781/7314/5595/5515/5516 15 Avian_infectious_bronchitis_virus R-HSA-180292 GAB1 signalosome 10/2292 17/10654 9.008390380542841e-4 0.002181668361251466 9.982503407338383e-4 5295/5290/2069/1950/6714/55824/1445/2885/1956/5781 10 Avian_infectious_bronchitis_virus R-HSA-9018677 Biosynthesis of DHA-derived SPMs 10/2292 17/10654 9.008390380542841e-4 0.002181668361251466 9.982503407338383e-4 1558/3248/246/1559/2948/1543/5743/1571/239/240 10 Avian_infectious_bronchitis_virus R-HSA-9020591 Interleukin-12 signaling 20/2292 47/10654 9.364630659392464e-4 0.0022597260938968773 0.0010339666574729668 6627/27250/5908/1265/3313/6175/3185/6950/3717/3458/3181/998/6648/302/4282/375/7297/5721/3586/829 20 Avian_infectious_bronchitis_virus R-HSA-9024446 NR1H2 and NR1H3-mediated signaling 20/2292 47/10654 9.364630659392464e-4 0.0022597260938968773 0.0010339666574729668 27161/8841/57690/27327/6720/192670/348/9611/2874/2194/9612/2033/192669/23028/23112/4343/1071/26523/29116/8648 20 Avian_infectious_bronchitis_virus R-HSA-6802952 Signaling by BRAF and RAF fusions 26/2292 67/10654 9.451236531930226e-4 0.0022765003726095954 0.0010416419438445993 4000/818/8805/4893/10018/8844/7094/5594/409/5908/7414/10533/6714/3717/2335/408/1445/5894/56829/8826/60/3845/3265/369/7529/5595 26 Avian_infectious_bronchitis_virus R-HSA-210990 PECAM1 interactions 8/2292 12/10654 9.689119297844973e-4 0.0023128865420662193 0.0010582909023679004 5777/3635/5335/6714/4067/2534/3932/5781 8 Avian_infectious_bronchitis_virus R-HSA-264870 Caspase-mediated cleavage of cytoskeletal proteins 8/2292 12/10654 9.689119297844973e-4 0.0023128865420662193 0.0010582909023679004 2934/841/5339/28988/836/6709/839/7431 8 Avian_infectious_bronchitis_virus R-HSA-389359 CD28 dependent Vav1 pathway 8/2292 12/10654 9.689119297844973e-4 0.0023128865420662193 0.0010582909023679004 941/2534/998/942/2885/7409/3932/940 8 Avian_infectious_bronchitis_virus R-HSA-8866907 Activation of the TFAP2 (AP-2) family of transcription factors 8/2292 12/10654 9.689119297844973e-4 0.0023128865420662193 0.0010582909023679004 7020/4435/7021/51741/10370/1387/2033/7022 8 Avian_infectious_bronchitis_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 8/2292 12/10654 9.689119297844973e-4 0.0023128865420662193 0.0010582909023679004 3665/7098/7316/6233/10010/7311/9641/7314 8 Avian_infectious_bronchitis_virus R-HSA-447115 Interleukin-12 family signaling 23/2292 57/10654 9.772540922791863e-4 0.002328626924715342 0.0010654931163349005 10148/6627/27250/5908/1265/3313/6175/3185/6774/6772/6950/3717/3458/3181/998/6648/302/4282/375/7297/5721/3586/829 23 Avian_infectious_bronchitis_virus R-HSA-622312 Inflammasomes 11/2292 20/10654 0.0010678564559724417 0.0025399728559915933 0.0011621971579098566 834/596/351/4790/58484/7295/5970/598/10628/3326/114548 11 Avian_infectious_bronchitis_virus R-HSA-114604 GPVI-mediated activation cascade 16/2292 35/10654 0.0011908464960143515 0.0028274644076490487 0.0012937426047327323 5295/5777/5590/5290/5336/6850/4067/2534/998/7410/7409/3932/387/5296/5781/1278 16 Avian_infectious_bronchitis_virus R-HSA-5654732 Negative regulation of FGFR3 signaling 14/2292 29/10654 0.0012445878539109891 0.002949806087917149 0.0013497216096918202 5594/7316/6714/867/2247/6233/2885/7311/5518/5781/7314/5595/5515/5516 14 Avian_infectious_bronchitis_virus R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 9/2292 15/10654 0.0013593959946415221 0.0031726411127924376 0.0014516826334019452 1499/1452/5519/2932/8312/5527/5518/5515/5516 9 Avian_infectious_bronchitis_virus R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 9/2292 15/10654 0.0013593959946415221 0.0031726411127924376 0.0014516826334019452 1499/1452/5519/2932/8312/5527/5518/5515/5516 9 Avian_infectious_bronchitis_virus R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 9/2292 15/10654 0.0013593959946415221 0.0031726411127924376 0.0014516826334019452 1499/1452/5519/2932/8312/5527/5518/5515/5516 9 Avian_infectious_bronchitis_virus R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 9/2292 15/10654 0.0013593959946415221 0.0031726411127924376 0.0014516826334019452 1499/1452/5519/2932/8312/5527/5518/5515/5516 9 Avian_infectious_bronchitis_virus R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 9/2292 15/10654 0.0013593959946415221 0.0031726411127924376 0.0014516826334019452 1499/1452/5519/2932/8312/5527/5518/5515/5516 9 Avian_infectious_bronchitis_virus R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 9/2292 15/10654 0.0013593959946415221 0.0031726411127924376 0.0014516826334019452 1499/1452/5519/2932/8312/5527/5518/5515/5516 9 Avian_infectious_bronchitis_virus R-HSA-8866910 TFAP2 (AP-2) family regulates transcription of growth factors and their receptors 9/2292 15/10654 0.0013593959946415221 0.0031726411127924376 0.0014516826334019452 7020/7021/3815/7422/2064/2099/7022/1956/7528 9 Avian_infectious_bronchitis_virus R-HSA-74749 Signal attenuation 7/2292 10/10654 0.0013648073255480982 0.0031726411127924376 0.0014516826334019452 6464/3667/5594/3630/6654/2885/5595 7 Avian_infectious_bronchitis_virus R-HSA-8853334 Signaling by FGFR3 fusions in cancer 7/2292 10/10654 0.0013648073255480982 0.0031726411127924376 0.0014516826334019452 5295/4893/5290/6654/2885/3845/3265 7 Avian_infectious_bronchitis_virus R-HSA-8875656 MET receptor recycling 7/2292 10/10654 0.0013648073255480982 0.0031726411127924376 0.0014516826334019452 3082/382/4233/2885/1398/5867/1399 7 Avian_infectious_bronchitis_virus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 7/2292 10/10654 0.0013648073255480982 0.0031726411127924376 0.0014516826334019452 6885/7316/10454/7189/6233/7311/7314 7 Avian_infectious_bronchitis_virus R-HSA-373760 L1CAM interactions 40/2292 119/10654 0.001460059882907267 0.0033822604591869213 0.0015475966539190986 6711/7430/6712/1459/51807/10048/286/5594/347688/1460/7277/10381/8650/1457/57731/285643/6714/6710/7846/6195/6708/287/7410/6709/51332/6196/1759/1213/10383/24137/1956/1211/60/84790/6197/3312/100133941/288/7280/5595 40 Avian_infectious_bronchitis_virus R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 40/2292 119/10654 0.001460059882907267 0.0033822604591869213 0.0015475966539190986 8841/5468/892/9440/4802/6721/9862/1543/57761/6720/6837/9611/5469/2874/4800/9612/1024/6667/23309/3156/1387/10001/2033/9967/4801/10498/183/2274/112950/10499/23054/1579/25942/9412/405/51586/8202/8648/10891/7296 40 Avian_infectious_bronchitis_virus R-HSA-1489509 DAG and IP3 signaling 18/2292 42/10654 0.0015079197944278403 0.003487064524614381 0.0015955510982706865 818/3838/5335/112/114/3708/108/113/111/107/3709/5136/5580/1385/3710/196883/115/109 18 Avian_infectious_bronchitis_virus R-HSA-73933 Resolution of Abasic Sites (AP sites) 17/2292 39/10654 0.00161763140895216 0.003734289491723184 0.001708672052874762 6118/328/4913/7515/5982/6996/5111/6119/5985/142/5984/4595/4968/5983/6117/5981/10714 17 Avian_infectious_bronchitis_virus R-HSA-111471 Apoptotic factor-mediated response 10/2292 18/10654 0.0016377770826711622 0.0037612397829620485 0.001721003504295105 1029/842/5594/54205/836/331/581/317/578/5595 10 Avian_infectious_bronchitis_virus R-HSA-210993 Tie2 Signaling 10/2292 18/10654 0.0016377770826711622 0.0037612397829620485 0.001721003504295105 5295/4893/6464/5290/6654/2885/5296/3845/3265/5781 10 Avian_infectious_bronchitis_virus R-HSA-5675482 Regulation of necroptotic cell death 10/2292 18/10654 0.0016377770826711622 0.0037612397829620485 0.001721003504295105 355/841/7316/8797/8837/6233/7311/331/8795/7314 10 Avian_infectious_bronchitis_virus R-HSA-416482 G alpha (12/13) signalling events 29/2292 80/10654 0.0017464562849170216 0.004003923875231451 0.001832046723375225 2788/54331/59345/29/27237/1894/10681/51764/94235/55970/9828/2792/2793/23365/2785/2783/2784/2768/2782/695/2786/6654/7410/7409/387/2791/2790/2787/10672 29 Avian_infectious_bronchitis_virus R-HSA-5654738 Signaling by FGFR2 27/2292 73/10654 0.0017680934280309294 0.00404656434044192 0.0018515574151381955 5295/4893/6464/5290/5335/5430/5594/3178/7316/3185/6714/867/4670/2247/6654/6233/2885/3187/7311/5518/3845/3265/5781/7314/5595/5515/5516 27 Avian_infectious_bronchitis_virus R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 11/2292 21/10654 0.00180931126014549 0.0041337951947063335 0.0018914710113284083 6118/328/5982/5111/6119/5985/5984/5983/6117/5981/10714 11 Avian_infectious_bronchitis_virus R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 12/2292 24/10654 0.001892822166041261 0.0043171902828201365 0.001975385786117322 6118/1763/5982/5422/5111/6119/5985/5984/5983/6117/5981/10714 12 Avian_infectious_bronchitis_virus R-HSA-912526 Interleukin receptor SHC signaling 13/2292 27/10654 0.0019089988377579304 0.004346643507510364 0.001988862486840921 5295/5777/3635/6464/5290/1437/3567/3558/3717/6654/2885/5293/5296 13 Avian_infectious_bronchitis_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 24/2292 63/10654 0.001965409712668705 0.004467450063608729 0.002044139076046668 1147/3665/6737/4790/1499/7520/51082/6778/4615/7098/5591/7316/5970/4792/4793/3428/1387/2033/22954/6233/7311/3551/2547/7314 24 Avian_infectious_bronchitis_virus R-HSA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 8/2292 13/10654 0.0020445791320029554 0.0046080869777122445 0.002108489299901525 7027/5925/5422/1869/5519/5518/5515/5516 8 Avian_infectious_bronchitis_virus R-HSA-171007 p38MAPK events 8/2292 13/10654 0.0020445791320029554 0.0046080869777122445 0.002108489299901525 4893/6714/1432/5603/3845/5600/3265/6300 8 Avian_infectious_bronchitis_virus R-HSA-179812 GRB2 events in EGFR signaling 8/2292 13/10654 0.0020445791320029554 0.0046080869777122445 0.002108489299901525 4893/2069/1950/6654/2885/1956/3845/3265 8 Avian_infectious_bronchitis_virus R-HSA-202670 ERKs are inactivated 8/2292 13/10654 0.0020445791320029554 0.0046080869777122445 0.002108489299901525 5594/5519/5598/5518/51231/5595/5515/5516 8 Avian_infectious_bronchitis_virus R-HSA-879415 Advanced glycosylation endproduct receptor signaling 8/2292 13/10654 0.0020445791320029554 0.0046080869777122445 0.002108489299901525 351/5594/830/3146/6288/6285/829/5595 8 Avian_infectious_bronchitis_virus R-HSA-2428924 IGF1R signaling cascade 21/2292 53/10654 0.0020941531898263483 0.004711844677109283 0.00215596496605522 5295/54106/4893/6464/5290/3667/57761/5289/2247/8471/2264/3481/208/6654/2885/3479/5296/3845/3265/5781/3480 21 Avian_leukosis_virus_RSA R-HSA-6794362 Protein-protein interactions at synapses 5/16 87/10654 1.3157801588092625e-7 2.381562087444765e-5 1.8282419048718176e-5 64130/55327/57596/1739/8825 5 Avian_leukosis_virus_RSA R-HSA-9609736 Assembly and cell surface presentation of NMDA receptors 4/16 41/10654 3.322427636415561e-7 3.0067970109560824e-5 2.3082128842466003e-5 64130/55327/1739/8825 4 Avian_leukosis_virus_RSA R-HSA-6794361 Neurexins and neuroligins 4/16 56/10654 1.1887720095879232e-6 7.17225779118047e-5 5.505891412828277e-5 64130/55327/57596/8825 4 Avian_leukosis_virus_RSA R-HSA-212676 Dopamine Neurotransmitter Release Cycle 3/16 23/10654 4.832660061040844e-6 2.186778677620982e-4 1.6787134948878724e-4 64130/55327/8825 3 Avian_leukosis_virus_RSA R-HSA-442755 Activation of NMDA receptors and postsynaptic events 4/16 93/10654 9.139045585113692e-6 3.308334501811157e-4 2.5396926678631737e-4 64130/55327/1739/8825 4 Avian_leukosis_virus_RSA R-HSA-112310 Neurotransmitter release cycle 3/16 51/10654 5.538739595935018e-5 0.001670853111440397 0.0012826554853744253 64130/55327/8825 3 Bean_golden_yellow_mosaic_virus R-HSA-1614635 Sulfur amino acid metabolism 7/96 28/10654 3.920864490543156e-9 1.8192811236120242e-6 1.5353279899811095e-6 23743/102724560/635/4548/4143/191/1491 7 Bean_golden_yellow_mosaic_virus R-HSA-71291 Metabolism of amino acids and derivatives 14/96 372/10654 5.554985689318106e-6 8.944207852706974e-4 7.548197189671041e-4 8659/9061/84706/6470/23743/27232/10993/102724560/635/4548/4143/191/1491/113675 14 Bean_golden_yellow_mosaic_virus R-HSA-156581 Methylation 4/96 14/10654 5.782893008215716e-6 8.944207852706974e-4 7.548197189671041e-4 4144/4548/4143/191 4 Bean_golden_yellow_mosaic_virus R-HSA-8951664 Neddylation 11/96 234/10654 7.739768457473307e-6 8.978131410669036e-4 7.576825963631765e-4 8454/4738/55832/9820/10987/9039/8452/8450/26270/9040/92591 11 Bluetongue_virus_10 R-HSA-5684996 MAPK1/MAPK3 signaling 193/1301 255/10654 1.4964441087557372e-125 1.936398676729924e-122 8.836896263283882e-123 5923/5718/22821/818/5786/5689/10156/815/9462/1839/5684/2674/3562/4893/6464/6711/685/1437/3667/71/8823/6712/5682/5604/8831/2904/2065/3561/5525/5747/153090/3815/283455/5526/8844/10048/817/3674/7094/84292/5690/7010/1439/5594/2069/2322/5717/2675/8074/409/5908/3082/7414/3568/8817/10817/2064/5921/4902/1438/2260/8452/54518/5528/4684/2254/2902/7316/10213/10125/673/152831/1950/3560/2676/8315/221002/2263/4233/983/3718/2668/57731/22866/2249/25780/26281/6714/5605/10818/64926/6710/5037/2248/5519/5711/64096/8437/10256/2261/5159/3567/3558/5922/3717/2247/2244/2255/54756/5708/53358/145957/3084/5692/5686/2335/2534/3690/408/9965/5529/1445/2264/816/5702/4296/2066/6708/27006/5894/3563/5979/1741/2906/9693/1742/6654/9542/1739/6233/5527/2885/10718/6709/51332/3716/88/2266/8660/2246/7311/8826/5906/2251/115727/5518/5155/2243/9048/7450/2252/1956/1740/5536/399473/4140/3845/5623/5694/3265/3559/369/801/200734/4763/5781/3569/5693/5924/5691/4747/5245/2323/7529/5156/7314/3572/161742/5595/25759/5515/284/5516 193 Bluetongue_virus_10 R-HSA-9607240 FLT3 Signaling 197/1301 267/10654 1.4415517053137051e-124 9.326839533379673e-122 4.2563710877946774e-122 5295/5923/5718/22821/818/5786/5689/10156/815/9462/1839/5684/2674/3562/4893/6464/6711/685/5290/1437/3667/71/8823/6712/5682/5291/5604/8831/2904/2065/3561/5525/5747/153090/3815/283455/5526/8844/10048/817/3674/7094/84292/5690/7010/1439/5594/2069/2322/5717/2675/8074/409/5908/3082/7414/3568/8817/10817/2064/5921/4902/1438/2260/8452/54518/5528/4684/2254/2902/7316/10213/10125/673/152831/1950/3560/2676/8315/221002/2263/4233/3055/3718/2668/57731/22866/2249/25780/26281/6714/5605/10818/64926/6710/5037/2248/5519/5711/64096/8437/10256/2261/5159/3567/3558/5922/3717/2247/2244/2255/54756/5708/53358/145957/3084/5692/5686/2335/2534/3690/408/9965/5529/1445/2264/816/5702/4296/2066/6708/27006/5894/3563/5979/1741/2906/9693/1742/6654/9542/1739/6233/5527/2885/10718/6709/51332/3716/88/2266/8660/2246/7311/8826/5906/2251/9846/115727/5518/5155/2243/9048/7450/2252/1956/1740/5536/5296/399473/4140/3845/2549/5623/5694/3265/3559/369/801/200734/4763/5781/5693/5924/5691/4747/5245/2323/7529/5156/7314/161742/5595/25759/5515/284/5516 197 Bluetongue_virus_10 R-HSA-5673001 RAF/MAP kinase cascade 189/1301 249/10654 2.8330858231036955e-123 1.2220043516987272e-120 5.5767057781093805e-121 5923/5718/22821/818/5786/5689/10156/815/9462/1839/5684/2674/3562/4893/6464/6711/685/1437/3667/71/8823/6712/5682/5604/8831/2904/2065/3561/5525/5747/153090/3815/283455/5526/8844/10048/817/3674/7094/84292/5690/7010/1439/5594/2069/2322/5717/2675/8074/409/5908/3082/7414/3568/8817/10817/2064/5921/4902/1438/2260/8452/54518/5528/4684/2254/2902/7316/10213/10125/673/152831/1950/3560/2676/8315/221002/2263/4233/3718/2668/57731/22866/2249/25780/26281/6714/5605/10818/64926/6710/5037/2248/5519/5711/64096/8437/10256/2261/5159/3567/3558/5922/3717/2247/2244/2255/54756/5708/53358/145957/3084/5692/5686/2335/2534/3690/408/9965/5529/1445/2264/816/5702/4296/2066/6708/27006/5894/3563/5979/1741/2906/9693/1742/6654/9542/1739/6233/5527/2885/10718/6709/51332/3716/88/2266/8660/2246/7311/8826/5906/2251/115727/5518/5155/2243/9048/7450/2252/1956/1740/5536/399473/4140/3845/5623/5694/3265/3559/369/801/200734/4763/5693/5924/5691/4747/5245/2323/7529/5156/7314/161742/5595/25759/5515/284/5516 189 Bluetongue_virus_10 R-HSA-5683057 MAPK family signaling cascades 202/1301 294/10654 6.485944149617404e-118 2.09820293240123e-115 9.575301757724641e-116 5923/5718/22821/818/5786/5689/3725/10156/815/9462/1839/5684/2674/3562/4893/6464/6711/685/1437/3667/71/8823/6712/5682/5604/8831/2904/2065/3561/5525/5747/153090/3815/283455/5526/8844/10048/817/3674/7094/84292/5690/7010/1439/5594/2069/2322/5717/2675/8074/3315/409/5908/3082/7414/3568/8817/10817/2064/5921/4902/1438/2260/8452/54518/5528/4684/2254/2902/7316/10213/10125/673/152831/1950/3560/2676/8315/221002/2263/4233/983/3718/2668/57731/22866/2249/25780/26281/6714/5605/4609/10818/64926/6710/5037/2248/5519/5711/64096/8437/10256/2261/5159/3567/3558/5922/3717/2247/2244/2255/54756/5708/53358/145957/3084/5692/5686/2335/5063/2534/3690/408/9965/5529/1445/2264/816/5702/4296/998/2066/6708/27006/5894/3563/5979/1741/2906/9693/1742/6654/9542/1739/6233/5527/2885/10718/6709/51332/3716/88/2266/8660/2246/7514/7311/8826/5906/2251/115727/5518/5155/2243/9048/7450/2252/1956/1740/5536/399473/4140/3845/5623/5694/3265/3559/369/5058/801/200734/4763/5781/3569/5062/5693/5924/5691/4747/5245/2323/7529/5156/7314/3572/5879/161742/5595/25759/5515/284/5516 202 Bluetongue_virus_10 R-HSA-5663202 Diseases of signal transduction 180/1301 377/10654 7.078670399129843e-68 1.8319598992948036e-65 8.360282302972299e-66 5295/4000/5718/27044/818/5689/815/8805/1839/5684/22906/4893/6464/685/5290/3667/71/79718/8087/8823/5682/5291/5604/1499/2065/10018/5525/10142/55750/3815/283455/5430/5526/8844/817/207/3674/5436/7094/1452/5690/5594/2069/9530/5717/8074/409/5908/3082/7414/8817/10533/55109/2064/23164/2260/54845/5431/54518/5528/84447/2254/7316/10213/673/152831/1950/8546/8315/6774/2263/4233/102/57085/22866/2249/26281/6714/5605/4609/10818/4089/22938/5037/2248/5519/9061/8503/5711/80853/10256/2261/5437/5159/3717/10827/2247/2244/2255/5708/145957/3320/3084/5692/5686/2335/2534/2033/3690/408/9965/55294/5728/5529/1445/2264/816/5702/4296/2066/27006/5894/6654/9542/6233/5527/2885/10718/79109/2475/2266/56829/8660/2246/4040/7311/79412/8826/5906/2251/9846/3932/5293/5518/5155/2243/7450/2252/6469/1956/11160/5296/1185/4140/9444/3845/2549/5694/3265/369/801/9715/4763/5781/4851/5432/5693/5663/11140/5691/5245/7529/5156/7314/5879/57670/253260/5595/5515/5516 180 Bluetongue_virus_10 R-HSA-6802957 Oncogenic MAPK signaling 67/1301 71/10654 8.474839527373282e-57 1.8277403914035044e-54 8.341026271677917e-55 4000/27044/818/815/8805/22906/4893/71/8087/5604/10018/10142/55750/283455/8844/817/3674/7094/5594/409/5908/7414/10533/55109/23164/54845/54518/673/8546/8315/57085/22866/6714/5605/5037/9061/80853/10256/3717/10827/2244/2335/3690/408/1445/816/4296/5894/2266/56829/8826/5906/2243/7450/1185/4140/9444/3845/3265/369/801/9715/4763/5245/7529/57670/5595 67 Bluetongue_virus_10 R-HSA-6802952 Signaling by BRAF and RAF fusions 63/1301 67/10654 3.5927090731837146e-53 6.641379343856752e-51 3.030841789557991e-51 4000/27044/818/815/8805/22906/4893/71/8087/5604/10018/10142/55750/283455/8844/817/3674/7094/5594/409/5908/7414/10533/55109/23164/54845/54518/673/8546/57085/22866/6714/5605/5037/9061/80853/10256/3717/10827/2244/2335/3690/408/1445/816/5894/2266/56829/8826/5906/2243/7450/1185/4140/9444/3845/3265/369/801/9715/7529/57670/5595 63 Bluetongue_virus_10 R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 181/1301 473/10654 2.8543687535064854e-50 4.61694145879674e-48 2.1069748298909715e-48 5295/4908/627/1173/3643/9402/5590/1839/9252/4893/6464/685/5290/3667/71/5899/8823/5579/23768/5770/4915/5291/1495/5604/1499/2904/2065/6461/5747/3815/5430/10048/207/5436/9550/7422/10458/5578/9114/5594/2069/2322/7074/1785/8074/3315/5908/3082/8817/10817/2064/382/5921/2260/54845/5431/5528/3688/2254/7316/673/152831/1500/1950/51072/527/3185/6774/2263/57498/4233/102/10768/10413/2249/26281/6714/5605/10818/26052/1281/2248/5519/5898/1003/3673/8503/5795/2261/10163/5437/5159/4067/3717/4909/2247/245972/2255/55824/53358/145957/3320/3084/23767/55845/2335/5063/2534/9475/3690/9965/64759/6195/3728/8471/1445/2264/5603/998/2066/83737/27006/1742/6654/9542/200958/6233/2885/7525/10718/79109/5580/2475/5900/8660/2246/23191/6093/6196/7311/5906/2251/9846/57610/3932/5518/5155/23163/387/2252/53834/1956/5296/5581/6197/3845/2549/3265/5058/801/200734/5781/8877/5062/5432/3480/5663/11140/4916/2323/7529/51382/5156/7314/5879/253260/161742/5595/25759/5515/5516 181 Bluetongue_virus_10 R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 70/1301 103/10654 3.823349679588412e-40 5.497127205986005e-38 2.5086540002913447e-38 5295/3643/1839/685/5305/5290/3667/8823/5291/2065/5525/3815/5526/207/5594/2069/8074/3082/8817/2064/2260/5528/2254/152831/1950/2263/4233/2249/26281/6714/10818/2248/5519/8503/2261/5159/2247/2255/145957/3084/2534/9965/5529/2264/2066/27006/7189/9542/5527/2885/10718/8660/2246/2251/3932/5293/5518/5155/2252/1956/5296/8394/2549/5781/5156/5879/5595/5515/3556/5516 70 Bluetongue_virus_10 R-HSA-199418 Negative regulation of the PI3K/AKT network 71/1301 110/10654 2.0606453918472236e-38 2.6664751370503074e-36 1.2168653313960974e-36 5295/3643/1839/685/5305/5290/3667/8823/5291/2065/5525/3815/5526/207/5594/2069/8074/3082/8817/2064/2260/5528/2254/152831/1950/2263/4233/2249/26281/6714/10818/2248/5519/8503/2261/5159/2247/2255/145957/3084/2534/9965/5728/5529/2264/2066/27006/7189/9542/5527/2885/10718/8660/2246/2251/3932/5293/5518/5155/2252/1956/5296/8394/2549/5781/5156/5879/5595/5515/3556/5516 71 Bluetongue_virus_10 R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 44/1301 47/10654 3.858267565672919e-37 3.566141592843398e-35 1.627434664919179e-35 818/815/4893/71/5604/283455/8844/817/3674/7094/5594/409/5908/7414/54518/673/8315/22866/6714/5605/5037/10256/3717/2244/2335/3690/408/1445/816/4296/5894/2266/8826/5906/2243/7450/4140/3845/3265/369/801/5245/7529/5595 44 Bluetongue_virus_10 R-HSA-6802949 Signaling by RAS mutants 44/1301 47/10654 3.858267565672919e-37 3.566141592843398e-35 1.627434664919179e-35 818/815/4893/71/5604/283455/8844/817/3674/7094/5594/409/5908/7414/54518/673/8315/22866/6714/5605/5037/10256/3717/2244/2335/3690/408/1445/816/4296/5894/2266/8826/5906/2243/7450/4140/3845/3265/369/801/5245/7529/5595 44 Bluetongue_virus_10 R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 44/1301 47/10654 3.858267565672919e-37 3.566141592843398e-35 1.627434664919179e-35 818/815/4893/71/5604/283455/8844/817/3674/7094/5594/409/5908/7414/54518/673/8315/22866/6714/5605/5037/10256/3717/2244/2335/3690/408/1445/816/4296/5894/2266/8826/5906/2243/7450/4140/3845/3265/369/801/5245/7529/5595 44 Bluetongue_virus_10 R-HSA-9649948 Signaling downstream of RAS mutants 44/1301 47/10654 3.858267565672919e-37 3.566141592843398e-35 1.627434664919179e-35 818/815/4893/71/5604/283455/8844/817/3674/7094/5594/409/5908/7414/54518/673/8315/22866/6714/5605/5037/10256/3717/2244/2335/3690/408/1445/816/4296/5894/2266/8826/5906/2243/7450/4140/3845/3265/369/801/5245/7529/5595 44 Bluetongue_virus_10 R-HSA-9006925 Intracellular signaling by second messengers 119/1301 305/10654 7.056109457469576e-34 6.087070425310421e-32 2.7778788811511807e-32 5295/5718/818/5689/3725/815/3643/3838/1839/5684/685/5305/5290/3667/8823/5682/5291/2065/5525/1459/3815/2146/5526/817/207/5690/5578/5594/2069/5717/8074/3082/1460/112/8817/114/2064/2260/5573/5528/2254/7316/10213/152831/1950/2263/1457/4233/10768/2249/26281/6714/10818/2248/5519/8503/5711/2261/5159/2247/2255/5708/145957/3084/5692/54815/5686/2534/9965/5728/5529/2264/816/5702/7157/2066/27006/7189/5371/9542/10542/6233/5527/2885/10718/79109/5580/2475/55004/8660/2246/7311/2251/3932/5293/5518/5155/2252/1956/5296/5581/8394/2549/115/5694/801/5781/64121/57521/5693/5691/5156/7314/5879/253260/5595/5515/3556/5516 119 Bluetongue_virus_10 R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 53/1301 75/10654 5.341479454428052e-32 4.319921508768687e-30 1.9714276144303537e-30 5295/1839/685/5290/3667/8823/5291/2065/3815/2069/8074/3082/8817/2064/2260/2254/152831/1950/2263/4233/2249/26281/6714/10818/2248/8503/2261/5159/2247/2255/145957/3084/2534/9965/2264/2066/27006/9542/2885/10718/8660/2246/2251/3932/5293/5155/2252/1956/5296/2549/5781/5156/5879 53 Bluetongue_virus_10 R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 35/1301 36/10654 2.3090936277210836e-31 1.757627737806519e-29 8.02106207524166e-30 4893/71/5604/283455/8844/3674/7094/5594/409/5908/7414/54518/673/22866/6714/5605/5037/10256/2244/2335/3690/408/1445/5894/2266/8826/5906/2243/7450/4140/3845/3265/369/7529/5595 35 Bluetongue_virus_10 R-HSA-5674135 MAP2K and MAPK activation 37/1301 40/10654 7.035085280024553e-31 5.057444640195428e-29 2.3080016620431433e-29 4893/71/5604/283455/8844/3674/7094/84292/5594/409/5908/7414/54518/673/22866/6714/5605/5037/10256/2244/54756/2335/3690/408/1445/5894/2266/8826/5906/2243/7450/4140/3845/3265/369/7529/5595 37 Bluetongue_virus_10 R-HSA-1257604 PIP3 activates AKT signaling 105/1301 264/10654 8.59210825857606e-31 5.851677940314433e-29 2.6704558077901223e-29 5295/5718/5689/3725/3643/1839/5684/685/5305/5290/3667/8823/5682/5291/2065/5525/1459/3815/2146/5526/207/5690/5594/2069/5717/8074/3082/1460/8817/2064/2260/5528/2254/7316/10213/152831/1950/2263/1457/4233/2249/26281/6714/10818/2248/5519/8503/5711/2261/5159/2247/2255/5708/145957/3084/5692/54815/5686/2534/9965/5728/5529/2264/5702/7157/2066/27006/7189/5371/9542/10542/6233/5527/2885/10718/79109/2475/55004/8660/2246/7311/2251/3932/5293/5518/5155/2252/1956/5296/8394/2549/5694/5781/64121/57521/5693/5691/5156/7314/5879/253260/5595/5515/3556/5516 105 Bluetongue_virus_10 R-HSA-190236 Signaling by FGFR 54/1301 87/10654 3.3169401757056296e-28 2.1460602936815425e-26 9.793702308267676e-27 5295/4893/6464/5290/8823/23768/5430/5436/5594/8074/8817/10817/2260/54845/5431/2254/7316/673/152831/3185/2263/2249/26281/6714/10818/2248/2261/5437/2247/2255/23767/9965/2264/27006/6654/6233/2885/2246/7311/2251/5518/2252/53834/3845/2549/3265/200734/5781/5432/7314/161742/5595/5515/5516 54 Bluetongue_virus_10 R-HSA-5654736 Signaling by FGFR1 40/1301 50/10654 5.19970042629384e-28 3.204005881725823e-26 1.4621713980705987e-26 5295/4893/6464/5290/23768/5594/8074/8817/10817/2260/2254/7316/673/2249/26281/6714/10818/2248/2247/2255/23767/27006/6654/6233/2885/2246/7311/2251/5518/53834/3845/2549/3265/200734/5781/7314/161742/5595/5515/5516 40 Bluetongue_virus_10 R-HSA-2219528 PI3K/AKT Signaling in Cancer 58/1301 101/10654 1.1772063490907669e-27 6.924113707833874e-26 3.159869673875217e-26 5295/1839/685/5290/3667/8823/5291/2065/3815/207/2069/8074/3082/8817/2064/2260/2254/152831/1950/2263/4233/2249/26281/6714/10818/2248/8503/2261/5159/2247/2255/145957/3084/2534/9965/5728/2264/2066/27006/9542/2885/10718/79109/2475/8660/2246/2251/3932/5293/5155/2252/1956/5296/2549/5781/5156/5879/253260 58 Bluetongue_virus_10 R-HSA-5654743 Signaling by FGFR4 35/1301 41/10654 1.557750836897335e-26 8.76404166497892e-25 3.999534185351968e-25 5295/4893/6464/5290/8823/5594/8074/8817/10817/2254/7316/673/152831/2249/26281/6714/10818/2247/9965/2264/6654/6233/2885/2246/7311/2251/5518/3845/2549/3265/5781/7314/5595/5515/5516 35 Bluetongue_virus_10 R-HSA-74751 Insulin receptor signalling cascade 40/1301 54/10654 1.0035475760108608e-25 5.4107940139918914e-24 2.4692552199214604e-24 5295/3643/4893/6464/5290/3667/8823/5291/5594/2322/8074/8817/2260/2254/152831/2263/2249/26281/10818/2248/2261/2247/2255/9965/2264/27006/6654/2885/8660/2246/2251/9846/2252/5296/3845/2549/3265/5781/2323/5595 40 Bluetongue_virus_10 R-HSA-5673000 RAF activation 30/1301 32/10654 1.1560479098297145e-25 5.983703981278602e-24 2.7307068522714523e-24 818/815/4893/5604/5525/5526/8844/817/5528/673/8315/6714/5605/5519/3717/5529/816/4296/5894/5527/5518/4140/3845/3265/369/801/5245/7529/5515/5516 30 Bluetongue_virus_10 R-HSA-2428924 IGF1R signaling cascade 39/1301 53/10654 6.252131188156716e-25 3.1116375990287656e-23 1.4200184601440963e-23 5295/4893/6464/5290/3667/8823/5291/2322/8074/8817/2260/2254/152831/2263/2249/26281/10818/2248/2261/2247/2255/9965/8471/2264/27006/6654/2885/8660/2246/2251/9846/2252/5296/3845/2549/3265/5781/3480/2323 39 Bluetongue_virus_10 R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 39/1301 54/10654 1.9898448579735938e-24 9.536515726732705e-23 4.352058344339907e-23 5295/4893/6464/5290/3667/8823/5291/2322/8074/8817/2260/2254/152831/2263/2249/26281/10818/2248/2261/2247/2255/9965/8471/2264/27006/6654/2885/8660/2246/2251/9846/2252/5296/3845/2549/3265/5781/3480/2323 39 Bluetongue_virus_10 R-HSA-2428928 IRS-related events triggered by IGF1R 38/1301 52/10654 3.866924467987228e-24 1.7870715219912406e-22 8.155430926845245e-23 5295/4893/5290/3667/8823/5291/2322/8074/8817/2260/2254/152831/2263/2249/26281/10818/2248/2261/2247/2255/9965/8471/2264/27006/6654/2885/8660/2246/2251/9846/2252/5296/3845/2549/3265/5781/3480/2323 38 Bluetongue_virus_10 R-HSA-166520 Signaling by NTRKs 54/1301 101/10654 8.90437340131176e-24 3.9731928211370403e-22 1.8131954548587652e-22 5295/4908/627/1173/9252/4893/6464/5290/3667/5899/4915/5291/5604/2904/5594/7074/1785/10817/5528/673/6774/57498/6714/5605/10818/26052/5519/5898/4909/53358/2534/6195/5603/6654/2885/5900/8660/6196/5906/5518/387/5296/6197/3845/2549/3265/5781/4916/7529/5879/5595/25759/5515/5516 54 Bluetongue_virus_10 R-HSA-376176 Signaling by ROBO receptors 84/1301 218/10654 1.074627831811142e-23 4.635228047878725e-22 2.1153200478808795e-22 10921/5718/5689/6138/6144/23032/6203/5684/8861/6194/2107/6234/6191/6128/5682/6132/6147/10298/6129/6222/6152/5690/6136/5578/5532/6125/5717/6224/6146/6154/6141/26986/2935/6134/6160/6091/7316/10213/4116/6714/6205/6165/6142/5711/1605/5708/5692/23767/5686/5063/6156/6235/9495/6124/5702/998/6207/9939/6139/10487/6654/6233/7311/6223/387/6655/6188/9775/6135/6161/5694/5058/6187/5062/6168/5693/6208/6157/5691/200916/6122/7314/5879/6230 84 Bluetongue_virus_10 R-HSA-112399 IRS-mediated signalling 36/1301 48/10654 1.373941114284764e-23 5.73509613511124e-22 2.617252852678277e-22 5295/4893/5290/3667/8823/5291/2322/8074/8817/2260/2254/152831/2263/2249/26281/10818/2248/2261/2247/2255/9965/2264/27006/6654/2885/8660/2246/2251/9846/2252/5296/3845/2549/3265/5781/2323 36 Bluetongue_virus_10 R-HSA-5663205 Infectious disease 118/1301 383/10654 5.835700262599141e-23 2.359811293688528e-21 1.0769170550388549e-21 5718/23165/5689/6138/8945/1173/4928/6144/3838/6917/81929/6203/1839/5684/6194/6234/6191/55706/79643/6128/5682/6132/9631/5604/1499/1938/6147/6129/3843/5430/6222/5436/6152/5690/6136/7520/6125/5717/4869/821/811/6224/6146/6154/6141/79023/57122/91782/6134/5431/6160/7316/10213/1500/6872/4233/3055/6714/5605/9688/6205/6165/6142/5711/23327/5437/89853/83860/999/5708/3320/5692/5686/2534/6156/6235/2068/6124/5702/2071/5902/6207/8086/6139/5609/6233/2885/3326/6844/7514/7311/6223/3932/93343/6188/11198/6396/6135/375/6161/5694/55690/2547/801/2961/6187/5062/5432/6168/5693/6208/6157/5691/200916/6122/7314/5879/6230 118 Bluetongue_virus_10 R-HSA-5654741 Signaling by FGFR3 32/1301 40/10654 1.2246042677791543e-22 4.801933098503714e-21 2.1913971107626974e-21 5295/4893/6464/5290/8823/5594/8074/8817/10817/2254/7316/673/2249/26281/6714/10818/2261/2247/6654/6233/2885/2246/7311/5518/3845/2549/3265/5781/7314/5595/5515/5516 32 Bluetongue_virus_10 R-HSA-1227986 Signaling by ERBB2 36/1301 50/10654 1.4456411723828113e-22 5.5019402266569354e-21 2.510850457296462e-21 5295/1839/4893/6464/685/5290/2065/207/5578/2069/2064/7316/1950/51072/6714/145957/3320/3084/2534/2066/6654/9542/6233/2885/7525/10718/5580/7311/387/1956/5581/3845/2549/3265/11140/7314 36 Bluetongue_virus_10 R-HSA-5654738 Signaling by FGFR2 44/1301 73/10654 1.840396628666646e-22 6.804209249984685e-21 3.1051504020510937e-21 5295/4893/6464/5290/8823/5430/5436/5594/8074/8817/10817/54845/5431/2254/7316/673/3185/2263/2249/26281/6714/10818/2248/5437/2247/2255/27006/6654/6233/2885/2246/7311/2251/5518/2252/3845/2549/3265/5781/5432/7314/5595/5515/5516 44 Bluetongue_virus_10 R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 35/1301 48/10654 2.8220004652363595e-22 1.0143523894488469e-20 4.629070938589467e-21 5295/3562/6464/5290/1437/5291/3561/1439/3568/1438/7534/7316/3560/3055/6850/3718/8503/3567/3558/4067/3717/2534/3563/6654/6233/2885/7525/3716/7311/9846/5293/5296/3559/5781/7314 35 Bluetongue_virus_10 R-HSA-74752 Signaling by Insulin receptor 45/1301 78/10654 7.640739586766541e-22 2.6721937906151092e-20 1.2194750805621706e-20 5295/3643/4893/6464/5290/3667/8823/5291/9550/9114/5594/2322/8074/8817/2260/2254/152831/527/2263/2249/26281/10818/2248/2261/2247/245972/2255/9965/2264/27006/6654/2885/8660/2246/2251/9846/2252/5296/3845/2549/3265/5781/2323/51382/5595 45 Bluetongue_virus_10 R-HSA-9010553 Regulation of expression of SLITs and ROBOs 69/1301 171/10654 5.577812197347603e-21 1.899391837728368e-19 8.668012860698078e-20 10921/5718/5689/6138/6144/23032/6203/5684/8861/6194/2107/6234/6191/6128/5682/6132/6147/6129/6222/6152/5690/6136/6125/5717/6224/6146/6154/6141/26986/2935/6134/6160/6091/7316/10213/4116/6205/6165/6142/5711/1605/5708/5692/5686/6156/6235/6124/5702/6207/9939/6139/6233/7311/6223/6188/9775/6135/6161/5694/6187/6168/5693/6208/6157/5691/200916/6122/7314/6230 69 Bluetongue_virus_10 R-HSA-5654727 Negative regulation of FGFR2 signaling 28/1301 34/10654 1.3371679206592951e-20 4.436654588033661e-19 2.024699604561038e-19 8823/5594/8074/8817/2254/7316/673/2263/2249/26281/6714/10818/2248/2247/2255/27006/6233/2885/2246/7311/2251/5518/2252/5781/7314/5595/5515/5516 28 Bluetongue_virus_10 R-HSA-109704 PI3K Cascade 32/1301 44/10654 2.0526378584615112e-20 6.5286085162323725e-19 2.979378001794811e-19 5295/5290/3667/8823/5291/2322/8074/8817/2260/2254/152831/2263/2249/26281/10818/2248/2261/2247/2255/9965/2264/27006/2885/8660/2246/2251/9846/2252/5296/2549/5781/2323 32 Bluetongue_virus_10 R-HSA-449147 Signaling by Interleukins 128/1301 461/10654 2.068569931727413e-20 6.5286085162323725e-19 2.979378001794811e-19 5295/5718/5689/3725/7291/8945/596/5684/5601/3562/351/9252/1072/6464/5290/1437/3667/4790/5682/5291/5604/3561/207/5292/9021/7422/5690/1439/5594/8878/4582/5717/821/5908/3082/5743/3568/246330/301/11009/4478/1438/7534/3313/332/5528/3688/7316/10213/3560/6352/3185/6774/5970/4792/3936/3055/6850/59307/3718/177/4609/6647/5519/5898/8503/5711/3567/3558/4067/3717/598/2247/5708/3320/5602/5692/5686/2335/2534/595/6195/3181/5702/998/7157/4001/3563/7189/5609/6654/6233/2885/7525/6844/3716/8660/6196/7311/6809/9846/3932/5293/5518/6845/6655/5296/6197/5599/5784/375/7334/5694/3312/3559/5781/3569/3162/5062/4170/5693/5691/7314/3572/5595/5515/3556/5516 128 Bluetongue_virus_10 R-HSA-5654696 Downstream signaling of activated FGFR2 26/1301 30/10654 2.4240369487432068e-20 7.468342408746928e-19 3.408232401616389e-19 5295/4893/6464/5290/8823/8074/8817/10817/2254/2263/2249/26281/10818/2248/2247/2255/27006/6654/2885/2246/2251/2252/3845/2549/3265/5781 26 Bluetongue_virus_10 R-HSA-168255 Influenza Life Cycle 61/1301 144/10654 5.866335601031323e-20 1.765357736682449e-18 8.056338487585245e-19 23165/6138/4928/6144/81929/6203/6194/6234/6191/55706/6128/6132/9631/6147/6129/3843/5430/6222/5436/6152/6136/6125/821/811/6224/6146/6154/6141/79023/57122/6134/5431/6160/9688/6205/6165/6142/5437/3320/6156/6235/6124/6207/8086/6139/6233/7514/7311/6223/6188/6396/6135/6161/6187/5432/6168/6208/6157/200916/6122/6230 61 Bluetongue_virus_10 R-HSA-5654733 Negative regulation of FGFR4 signaling 26/1301 31/10654 1.3293467610208413e-19 3.8850916074663984e-018 1.77298982493179e-18 8823/5594/8074/8817/2254/7316/673/152831/2249/26281/6714/10818/2247/9965/2264/6233/2885/2246/7311/2251/5518/5781/7314/5595/5515/5516 26 Bluetongue_virus_10 R-HSA-168273 Influenza Viral RNA Transcription and Replication 58/1301 134/10654 1.3810990258381323e-19 3.8850916074663984e-018 1.77298982493179e-18 23165/6138/4928/6144/81929/6203/6194/6234/6191/55706/6128/6132/9631/6147/6129/3843/5430/6222/5436/6152/6136/6125/6224/6146/6154/6141/79023/57122/6134/5431/6160/9688/6205/6165/6142/5437/3320/6156/6235/6124/6207/8086/6139/6233/7311/6223/6188/6396/6135/6161/6187/5432/6168/6208/6157/200916/6122/6230 58 Bluetongue_virus_10 R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 58/1301 134/10654 1.3810990258381323e-19 3.8850916074663984e-018 1.77298982493179e-18 5295/5718/5689/3725/8945/9402/5684/5601/4893/6464/5290/4790/5682/5291/7321/5690/5532/5594/5717/7316/10213/10125/5970/4792/6850/10768/5711/4067/5708/5602/5692/5686/2534/5702/695/7189/5609/6654/6233/2885/10235/7311/9846/115727/5296/3845/5599/7334/5694/3265/5058/801/5062/5693/5691/7314/5879/5595 58 Bluetongue_virus_10 R-HSA-72613 Eukaryotic Translation Initiation 54/1301 119/10654 1.8027616591372195e-19 4.859944972757421e-18 2.217871251701711e-18 6138/6144/6203/8891/6194/1965/6234/6191/6128/6132/6147/8666/6129/6222/1983/6152/6136/8668/6125/6224/6146/6154/6141/26986/6134/6160/8661/9669/6205/6165/6142/8663/8894/6156/6235/6124/6207/6139/6233/7311/6223/8664/3646/6188/6135/6161/6187/6168/6208/6157/200916/6122/1968/6230 54 Bluetongue_virus_10 R-HSA-72737 Cap-dependent Translation Initiation 54/1301 119/10654 1.8027616591372195e-19 4.859944972757421e-18 2.217871251701711e-18 6138/6144/6203/8891/6194/1965/6234/6191/6128/6132/6147/8666/6129/6222/1983/6152/6136/8668/6125/6224/6146/6154/6141/26986/6134/6160/8661/9669/6205/6165/6142/8663/8894/6156/6235/6124/6207/6139/6233/7311/6223/8664/3646/6188/6135/6161/6187/6168/6208/6157/200916/6122/1968/6230 54 Bluetongue_virus_10 R-HSA-5654716 Downstream signaling of activated FGFR4 24/1301 27/10654 2.0296065791245398e-19 5.252621826774309e-18 2.397072191344983e-18 5295/4893/6464/5290/8823/8074/8817/10817/2254/152831/2249/26281/10818/2247/9965/2264/6654/2885/2246/2251/3845/2549/3265/5781 24 Bluetongue_virus_10 R-HSA-912526 Interleukin receptor SHC signaling 24/1301 27/10654 2.0296065791245398e-19 5.252621826774309e-18 2.397072191344983e-18 5295/3562/6464/5290/1437/5291/3561/1439/3568/1438/3560/3718/8503/3567/3558/3717/3563/6654/2885/3716/9846/5293/5296/3559 24 Bluetongue_virus_10 R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 52/1301 112/10654 2.405401636122455e-19 6.103117092436189e-18 2.7852018944575798e-18 6138/6144/6203/6194/1965/6234/6191/6128/6132/6147/8666/6129/6222/1983/6152/6136/8668/6125/6224/6146/6154/6141/6134/6160/8661/9669/6205/6165/6142/8663/8894/6156/6235/6124/6207/6139/6233/7311/6223/8664/3646/6188/6135/6161/6187/6168/6208/6157/200916/6122/1968/6230 52 Bluetongue_virus_10 R-HSA-187037 Signaling by NTRK1 (TRKA) 43/1301 80/10654 2.6201674831826053e-19 6.520186006227483e-18 2.9755343280676958e-18 5295/1173/9252/4893/6464/5290/3667/5899/4915/5291/5604/5594/1785/5528/673/6774/57498/6714/5605/10818/26052/5519/5898/53358/6195/5603/6654/2885/5900/8660/6196/5906/5518/387/5296/6197/3845/3265/7529/5595/25759/5515/5516 43 Bluetongue_virus_10 R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 25/1301 30/10654 9.292312107680474e-19 2.253455249375519e-17 1.0283807003169822e-17 5923/818/815/4893/2904/817/5594/2902/27330/6195/816/1741/2906/1742/1739/88/6196/1740/6197/3845/3265/801/5924/4747/5595 25 Bluetongue_virus_10 R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 51/1301 111/10654 9.452880202873005e-19 2.253455249375519e-17 1.0283807003169822e-17 6138/6144/6203/6194/1965/6234/6191/6128/6132/6147/8666/6129/6222/6152/6136/8668/6125/6224/6146/6154/6141/26986/6134/6160/8661/6205/6165/6142/8663/8894/6156/6235/6124/6207/6139/6233/7311/6223/8664/3646/6188/6135/6161/6187/6168/6208/6157/200916/6122/1968/6230 51 Bluetongue_virus_10 R-HSA-168254 Influenza Infection 62/1301 155/10654 9.57805554216797e-19 2.253455249375519e-17 1.0283807003169822e-17 23165/6138/4928/6144/3838/81929/6203/6194/6234/6191/55706/6128/6132/9631/6147/6129/3843/5430/6222/5436/6152/6136/6125/821/811/6224/6146/6154/6141/79023/57122/6134/5431/6160/9688/6205/6165/6142/5437/3320/6156/6235/6124/6207/8086/6139/6233/7514/7311/6223/6188/6396/6135/6161/6187/5432/6168/6208/6157/200916/6122/6230 62 Bluetongue_virus_10 R-HSA-1250196 SHC1 events in ERBB2 signaling 21/1301 22/10654 1.1208850779531538e-18 2.5900451622703234e-17 1.1819859562626304e-17 1839/4893/6464/685/2065/5578/2069/2064/1950/145957/3084/2066/6654/9542/2885/10718/5580/1956/5581/3845/3265 21 Bluetongue_virus_10 R-HSA-5675221 Negative regulation of MAPK pathway 29/1301 40/10654 1.4886474447735706e-18 3.379490865854386e-17 1.5422552474939484e-17 4893/5604/5525/5526/8844/5594/5528/7316/673/8315/5605/5037/5519/5529/5894/6233/5527/7311/5518/5536/4140/3845/3265/369/7529/7314/5595/5515/5516 29 Bluetongue_virus_10 R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 51/1301 112/10654 1.534503441441853e-18 3.4235300917685476e-17 1.5623528686912517e-17 6138/6144/6203/6194/6234/6191/6128/10952/6132/6147/6129/6222/6152/6136/6125/6727/6224/6146/6154/6141/58477/6134/6160/29927/6729/6205/6165/6142/28972/6156/6235/6124/6207/6139/6745/6726/6233/7311/6223/6730/6188/9789/6135/6161/6187/6168/6208/6157/200916/6122/6230 51 Bluetongue_virus_10 R-HSA-4420097 VEGFA-VEGFR2 Pathway 47/1301 99/10654 4.235629117093933e-18 9.159651115790733e-17 4.1800734368816415e-17 5295/5590/4893/5290/71/5579/5291/1495/1499/6461/5747/207/7422/10458/5578/3315/5921/1500/10768/6714/1003/10163/3320/55845/5063/2534/9475/3690/3728/5603/998/79109/5580/2475/23191/6093/387/5296/3845/3265/5058/801/8877/5062/5879/253260/25759 47 Bluetongue_virus_10 R-HSA-5654687 Downstream signaling of activated FGFR1 25/1301 31/10654 4.247133438542844e-18 9.159651115790733e-17 4.1800734368816415e-17 5295/4893/6464/5290/23768/8074/10817/2260/2254/2249/26281/10818/2248/2247/2255/23767/27006/6654/2885/2246/2251/3845/2549/3265/5781 25 Bluetongue_virus_10 R-HSA-927802 Nonsense-Mediated Decay (NMD) 51/1301 115/10654 6.2845580331720295e-18 1.3116480798265495e-16 5.985801454345517e-17 10921/6138/6144/6203/6194/2107/6234/6191/6128/6132/6147/6129/6222/6152/6136/6125/6224/6146/6154/6141/26986/2935/6134/6160/4116/6205/6165/6142/6156/6235/6124/6207/9939/6139/6233/7311/6223/5518/6188/23293/9775/6135/6161/6187/6168/6208/6157/200916/6122/5515/6230 51 Bluetongue_virus_10 R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 51/1301 115/10654 6.2845580331720295e-18 1.3116480798265495e-16 5.985801454345517e-17 10921/6138/6144/6203/6194/2107/6234/6191/6128/6132/6147/6129/6222/6152/6136/6125/6224/6146/6154/6141/26986/2935/6134/6160/4116/6205/6165/6142/6156/6235/6124/6207/9939/6139/6233/7311/6223/5518/6188/23293/9775/6135/6161/6187/6168/6208/6157/200916/6122/5515/6230 51 Bluetongue_virus_10 R-HSA-5654700 FRS-mediated FGFR2 signaling 22/1301 25/10654 1.1045618709278147e-17 2.268735017429512e-16 1.0353537336516358e-16 4893/8823/8074/8817/10817/2254/2263/2249/26281/10818/2248/2247/2255/27006/6654/2885/2246/2251/2252/3845/3265/5781 22 Bluetongue_virus_10 R-HSA-72689 Formation of a pool of free 40S subunits 47/1301 101/10654 1.1682967792670835e-17 2.3621500505806345e-16 1.0779843637645294e-16 6138/6144/6203/6194/6234/6191/6128/6132/6147/8666/6129/6222/6152/6136/8668/6125/6224/6146/6154/6141/6134/6160/8661/6205/6165/6142/8663/6156/6235/6124/6207/6139/6233/7311/6223/8664/3646/6188/6135/6161/6187/6168/6208/6157/200916/6122/6230 47 Bluetongue_virus_10 R-HSA-1226099 Signaling by FGFR in disease 36/1301 63/10654 1.5213338567541226e-17 3.0286246317535916e-16 1.3821348884843122e-16 5295/8805/4893/5290/8823/5430/5436/9530/8074/8817/2260/5431/2254/6774/2263/2249/26281/10818/2248/2261/5437/2247/2255/2264/27006/6654/2885/2246/2251/9846/2252/11160/3845/2549/3265/5432 36 Bluetongue_virus_10 R-HSA-156902 Peptide chain elongation 43/1301 89/10654 4.98683864049282e-17 9.77722606181471e-16 4.461908257283051e-16 6138/6144/6203/6194/6234/6191/6128/6132/1938/6147/6129/1915/6222/6152/6136/6125/6224/6146/6154/6141/6134/6160/6205/6165/6142/6156/6235/6124/6207/6139/6233/7311/6223/6188/6135/6161/6187/6168/6208/6157/200916/6122/6230 43 Bluetongue_virus_10 R-HSA-5654726 Negative regulation of FGFR1 signaling 25/1301 33/10654 6.267789177600612e-17 1.210525253106745e-15 5.524320076408396e-16 5594/8074/2260/2254/7316/673/2249/26281/6714/10818/2248/2247/2255/27006/6233/2885/2246/7311/2251/5518/5781/7314/5595/5515/5516 25 Bluetongue_virus_10 R-HSA-5654712 FRS-mediated FGFR4 signaling 20/1301 22/10654 8.651196884683296e-17 1.646271877761792e-15 7.512881505119706e-16 4893/8823/8074/8817/10817/2254/152831/2249/26281/10818/2247/9965/2264/6654/2885/2246/2251/3845/3265/5781 20 Bluetongue_virus_10 R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 44/1301 95/10654 1.6118502442142207e-16 3.0228032116133357e-15 1.3794782410437498e-15 6138/6144/6203/6194/2107/6234/6191/6128/6132/6147/6129/6222/6152/6136/6125/6224/6146/6154/6141/26986/2935/6134/6160/6205/6165/6142/6156/6235/6124/6207/6139/6233/7311/6223/6188/6135/6161/6187/6168/6208/6157/200916/6122/6230 44 Bluetongue_virus_10 R-HSA-5654732 Negative regulation of FGFR3 signaling 23/1301 29/10654 1.900398029220555e-16 3.5130214997305687e-15 1.6031929238988444e-15 8823/5594/8074/8817/2254/7316/673/2249/26281/6714/10818/2261/2247/6233/2885/2246/7311/5518/5781/7314/5595/5515/5516 23 Bluetongue_virus_10 R-HSA-194138 Signaling by VEGF 47/1301 107/10654 2.013618068959326e-16 3.669889832723053e-15 1.6747809291122047e-15 5295/5590/4893/5290/71/5579/5291/1495/1499/6461/5747/207/7422/10458/5578/3315/5921/1500/10768/6714/1003/10163/3320/55845/5063/2534/9475/3690/3728/5603/998/79109/5580/2475/23191/6093/387/5296/3845/3265/5058/801/8877/5062/5879/253260/25759 47 Bluetongue_virus_10 R-HSA-354192 Integrin alphaIIb beta3 signaling 22/1301 27/10654 3.0365558325453825e-16 5.382607188100993e-15 2.456391956824744e-15 6464/5770/5747/207/3674/7094/5908/54518/10125/6850/6714/2244/2335/3690/1445/6654/2885/2266/10235/5906/2243/7450 22 Bluetongue_virus_10 R-HSA-9006921 Integrin signaling 22/1301 27/10654 3.0365558325453825e-16 5.382607188100993e-15 2.456391956824744e-15 6464/5770/5747/207/3674/7094/5908/54518/10125/6850/6714/2244/2335/3690/1445/6654/2885/2266/10235/5906/2243/7450 22 Bluetongue_virus_10 R-HSA-76002 Platelet activation, signaling and aggregation 81/1301 262/10654 3.745693574775587e-16 6.5499020077832565e-15 2.989095441606123e-15 5295/5099/5590/351/1072/6464/5290/5579/5770/5291/5747/59345/2770/207/3674/26090/7094/7422/5578/5594/409/5908/3082/7414/10490/334/7534/54518/10125/1950/51706/308/6850/6714/6647/7273/8503/146850/226/4067/2244/2335/5294/2534/3690/408/2783/2784/2768/1445/2782/998/2776/5894/2771/2/94121/10487/6654/2885/5580/88/2266/10235/5906/3932/5155/2243/7450/387/5296/5581/29789/801/5781/9002/2773/6814/5879/5595/2787 81 Bluetongue_virus_10 R-HSA-156842 Eukaryotic Translation Elongation 43/1301 93/10654 3.861974678846389e-16 6.575520045298984e-15 3.0007864194360448e-15 6138/6144/6203/6194/6234/6191/6128/6132/1938/6147/6129/1915/6222/6152/6136/6125/6224/6146/6154/6141/6134/6160/6205/6165/6142/6156/6235/6124/6207/6139/6233/7311/6223/6188/6135/6161/6187/6168/6208/6157/200916/6122/6230 43 Bluetongue_virus_10 R-HSA-72764 Eukaryotic Translation Termination 43/1301 93/10654 3.861974678846389e-16 6.575520045298984e-15 3.0007864194360448e-15 6138/6144/6203/6194/2107/6234/6191/6128/6132/6147/6129/6222/6152/6136/6125/6224/6146/6154/6141/2935/6134/6160/6205/6165/6142/6156/6235/6124/6207/6139/6233/7311/6223/6188/6135/6161/6187/6168/6208/6157/200916/6122/6230 43 Bluetongue_virus_10 R-HSA-5658442 Regulation of RAS by GAPs 36/1301 68/10654 4.254435330362996e-16 7.149661451285347e-15 3.2628000277971857e-15 5718/22821/5689/10156/9462/5684/4893/5682/8831/153090/5690/5717/5921/8452/7316/10213/64926/5711/8437/5922/5708/5692/5686/5702/6233/7311/399473/3845/5694/3265/200734/4763/5693/5691/7314/161742 36 Bluetongue_virus_10 R-HSA-5654708 Downstream signaling of activated FGFR3 21/1301 25/10654 4.469462702992045e-16 7.320866756546462e-15 3.3409308146282973e-15 5295/4893/6464/5290/8823/8074/8817/10817/2254/2249/26281/10818/2261/2247/6654/2885/2246/3845/2549/3265/5781 21 Bluetongue_virus_10 R-HSA-9006115 Signaling by NTRK2 (TRKB) 21/1301 25/10654 4.469462702992045e-16 7.320866756546462e-15 3.3409308146282973e-15 5295/4908/627/4893/6464/5290/4915/2904/7074/10817/6714/10818/4909/2534/6654/2885/3845/2549/3265/5781/5879 21 Bluetongue_virus_10 R-HSA-5655253 Signaling by FGFR2 in disease 28/1301 43/10654 4.987695104949238e-16 8.067596832255394e-15 3.6817065182585835e-15 5295/4893/5290/8823/5430/5436/8074/8817/5431/2254/2263/2249/26281/10818/2248/5437/2247/2255/27006/6654/2885/2246/2251/2252/3845/2549/3265/5432 28 Bluetongue_virus_10 R-HSA-5654695 PI-3K cascade:FGFR2 20/1301 23/10654 5.871967094555669e-16 9.266250512628093e-15 4.228720847298756e-15 5295/5290/8823/8074/8817/2254/2263/2249/26281/10818/2248/2247/2255/27006/2885/2246/2251/2252/2549/5781 20 Bluetongue_virus_10 R-HSA-5654699 SHC-mediated cascade:FGFR2 20/1301 23/10654 5.871967094555669e-16 9.266250512628093e-15 4.228720847298756e-15 4893/6464/8823/8074/8817/2254/2263/2249/26281/2248/2247/2255/27006/6654/2885/2246/2251/2252/3845/3265 20 Bluetongue_virus_10 R-HSA-8853659 RET signaling 27/1301 41/10654 1.0952812769018984e-15 1.7075830991699477e-14 7.792679725326126e-15 5295/2674/6464/5290/5291/5578/2675/4902/2676/2668/6714/10818/8503/64096/53358/5979/6654/2885/8660/9846/5293/9048/5296/2549/5623/5781/9046 27 Bluetongue_virus_10 R-HSA-451927 Interleukin-2 family signaling 28/1301 44/10654 1.2131405399828219e-15 1.868814117544966e-14 8.528469209653673e-15 5295/3562/6464/5290/1437/5291/3561/1439/3568/1438/3560/6774/6850/3718/8503/3567/3558/3717/3563/6654/2885/3716/9846/3932/5293/6655/5296/3559 28 Bluetongue_virus_10 R-HSA-192823 Viral mRNA Translation 41/1301 89/10654 2.2136674007353205e-15 3.352160018646726e-14 1.5297826164978557e-14 6138/6144/6203/6194/6234/6191/6128/6132/6147/6129/6222/6152/6136/6125/6224/6146/6154/6141/6134/6160/6205/6165/6142/6156/6235/6124/6207/6139/6233/7311/6223/6188/6135/6161/6187/6168/6208/6157/200916/6122/6230 41 Bluetongue_virus_10 R-HSA-1963640 GRB2 events in ERBB2 signaling 16/1301 16/10654 2.2537706462307976e-15 3.352160018646726e-14 1.5297826164978557e-14 1839/4893/685/2069/2064/1950/145957/3084/2066/6654/9542/2885/10718/1956/3845/3265 16 Bluetongue_virus_10 R-HSA-1963642 PI3K events in ERBB2 signaling 16/1301 16/10654 2.2537706462307976e-15 3.352160018646726e-14 1.5297826164978557e-14 5295/1839/685/5290/2065/2069/2064/1950/145957/3084/2066/9542/2885/10718/1956/2549 16 Bluetongue_virus_10 R-HSA-2408557 Selenocysteine synthesis 42/1301 93/10654 2.4253540042574645e-15 3.5663728198967716e-14 1.6275401870675092e-14 6138/6144/6203/6194/6234/6191/6128/6132/6147/6129/6222/6152/6136/6125/6224/6146/6154/6141/6134/60678/6160/6205/6165/6142/6156/6235/6124/6207/6139/6233/7311/6223/6188/6135/6161/6187/6168/6208/6157/200916/6122/6230 42 Bluetongue_virus_10 R-HSA-442982 Ras activation upon Ca2+ influx through NMDA receptor 19/1301 22/10654 4.23883658831019e-15 6.162982635138636e-14 2.8125219704813912e-14 5923/818/815/4893/2904/817/2902/816/1741/2906/1742/1739/88/1740/3845/3265/801/5924/4747 19 Bluetongue_virus_10 R-HSA-5654719 SHC-mediated cascade:FGFR4 18/1301 20/10654 4.898477472377136e-15 6.96552730687474e-14 3.1787690711435206e-14 4893/6464/8823/8074/8817/2254/152831/2249/26281/2247/9965/2264/6654/2885/2246/2251/3845/3265 18 Bluetongue_virus_10 R-HSA-5654720 PI-3K cascade:FGFR4 18/1301 20/10654 4.898477472377136e-15 6.96552730687474e-14 3.1787690711435206e-14 5295/5290/8823/8074/8817/2254/152831/2249/26281/10818/2247/9965/2264/2885/2246/2251/2549/5781 18 Bluetongue_virus_10 R-HSA-1643713 Signaling by EGFR in Cancer 20/1301 25/10654 1.3808373128378553e-14 1.9421776987088964e-13 8.863269250595388e-14 5295/1839/4893/6464/685/5290/2069/7316/1950/3320/6654/6233/2885/7311/1956/3845/2549/3265/11140/7314 20 Bluetongue_virus_10 R-HSA-354194 GRB2:SOS provides linkage to MAPK signaling for Integrins 15/1301 15/10654 1.8645307857892325e-14 2.594304125603513e-13 1.1839295651700728e-13 5747/3674/7094/5908/54518/6714/2244/2335/3690/6654/2885/2266/5906/2243/7450 15 Bluetongue_virus_10 R-HSA-5654693 FRS-mediated FGFR1 signaling 19/1301 23/10654 2.158412601286964e-14 2.946674329112969e-13 1.3447362715629838e-13 4893/8074/10817/2260/2254/2249/26281/10818/2248/2247/2255/27006/6654/2885/2246/2251/3845/3265/5781 19 Bluetongue_virus_10 R-HSA-8848021 Signaling by PTK6 30/1301 54/10654 2.1860953291719093e-14 2.946674329112969e-13 1.3447362715629838e-13 1839/1019/4893/685/5770/2065/207/2909/9021/2069/2064/5921/7316/1950/6774/6421/145957/3084/595/2066/9542/6233/10718/7311/387/1956/3845/3265/7314/5879 30 Bluetongue_virus_10 R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 30/1301 54/10654 2.1860953291719093e-14 2.946674329112969e-13 1.3447362715629838e-13 1839/1019/4893/685/5770/2065/207/2909/9021/2069/2064/5921/7316/1950/6774/6421/145957/3084/595/2066/9542/6233/10718/7311/387/1956/3845/3265/7314/5879 30 Bluetongue_virus_10 R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 17/1301 19/10654 3.654510806742127e-14 4.825445901963584e-13 2.2021273497124956e-13 5295/4893/6464/5290/7316/1950/3320/6654/6233/2885/7311/1956/3845/2549/3265/11140/7314 17 Bluetongue_virus_10 R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 17/1301 19/10654 3.654510806742127e-14 4.825445901963584e-13 2.2021273497124956e-13 5295/4893/6464/5290/7316/1950/3320/6654/6233/2885/7311/1956/3845/2549/3265/11140/7314 17 Bluetongue_virus_10 R-HSA-373760 L1CAM interactions 46/1301 119/10654 1.3619376298914892e-13 1.7801487808884717e-12 8.123838494089586e-13 1173/9252/6711/71/7430/6712/5604/1459/10048/3674/5594/1785/1460/10381/3678/4478/2260/4684/3688/8650/1457/57731/6714/5605/26052/6710/3673/27330/3690/6195/6708/1741/2048/1742/1739/287/6709/51332/6196/24137/1956/6197/3312/5058/5879/5595 46 Bluetongue_virus_10 R-HSA-5655332 Signaling by FGFR3 in disease 18/1301 22/10654 1.4797626227959315e-13 1.895854290988055e-12 8.65186900873911e-13 5295/4893/5290/8823/8074/8817/2254/2249/26281/10818/2261/2247/6654/2885/2246/3845/2549/3265 18 Bluetongue_virus_10 R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 18/1301 22/10654 1.4797626227959315e-13 1.895854290988055e-12 8.65186900873911e-13 5295/4893/5290/8823/8074/8817/2254/2249/26281/10818/2261/2247/6654/2885/2246/3845/2549/3265 18 Bluetongue_virus_10 R-HSA-1250347 SHC1 events in ERBB4 signaling 14/1301 14/10654 1.5414613489353081e-13 1.955540181884597e-12 8.924249914888627e-13 1839/4893/6464/685/2069/145957/3084/2066/6654/9542/2885/10718/3845/3265 14 Bluetongue_virus_10 R-HSA-5654706 FRS-mediated FGFR3 signaling 17/1301 20/10654 2.1587601477267066e-13 2.712073428309086e-12 1.2376744434079536e-12 4893/8823/8074/8817/10817/2254/2249/26281/10818/2261/2247/6654/2885/2246/3845/3265/5781 17 Bluetongue_virus_10 R-HSA-8868773 rRNA processing in the nucleus and cytosol 62/1301 195/10654 2.9386523893384617e-13 3.656361722888432e-12 1.6686072777518998e-12 9136/6138/6144/2091/6203/55651/55813/6194/6234/6191/6128/6132/6147/25879/6129/6222/6152/6136/10528/6125/4839/6224/6146/6154/6141/88745/51602/134430/6134/6160/55272/92856/5394/6205/6165/6142/9790/51077/6156/6235/10199/6124/6207/6139/6233/7311/6223/55505/6188/6135/6161/54881/51202/6187/4691/6168/6208/54512/6157/200916/6122/6230 62 Bluetongue_virus_10 R-HSA-9620244 Long-term potentiation 19/1301 25/10654 3.3856817102053934e-13 4.1724496504816944e-12 1.9041277588222817e-12 818/815/2904/817/2902/6714/2905/2903/3084/816/2066/1741/2906/1742/1739/88/1740/801/4747 19 Bluetongue_virus_10 R-HSA-3928662 EPHB-mediated forward signaling 25/1301 42/10654 3.818038274812416e-13 4.66088823359176e-12 2.127030260347334e-12 1072/71/2904/5747/1947/7074/1949/5921/2902/10094/6714/4067/2534/9475/998/1948/2048/7525/10097/6093/387/3265/5058/10109/5879 25 Bluetongue_virus_10 R-HSA-9009391 Extra-nuclear estrogen signaling 35/1301 77/10654 4.116570192529535e-13 4.978356849657214e-12 2.271909373348814e-12 5295/596/5590/1839/4893/6464/685/5290/5747/59345/2770/207/5594/2069/3315/1950/6714/8503/3320/595/2783/2784/2782/2771/7514/1956/5296/3845/3265/801/8877/3480/2773/5595/2787 35 Bluetongue_virus_10 R-HSA-2408522 Selenoamino acid metabolism 45/1301 118/10654 4.4421528367234865e-13 5.322357195111288e-12 2.4288964341148888e-12 6138/6144/6203/6194/6234/6191/6128/6132/6147/6129/4143/6222/6152/6136/6125/11185/6224/6146/6154/6141/6134/60678/6160/6205/6165/6142/9061/6156/6235/6124/6207/6139/6233/7311/6223/6188/6135/6161/6187/6168/6208/6157/200916/6122/6230 45 Bluetongue_virus_10 R-HSA-2555396 Mitotic Metaphase and Anaphase 63/1301 202/10654 5.012879774883174e-13 5.951070118072319e-12 2.7158141513369976e-12 4000/5718/5689/4928/26271/81929/5684/55143/5682/5525/7321/5526/8697/5690/9212/5717/79023/10381/57122/64105/332/8881/5528/7316/10213/5501/5519/5711/7444/5708/5692/5686/8243/9126/5529/5702/51529/2010/4001/64682/29945/10393/11004/23592/6233/5527/7514/7311/9184/5518/5347/29882/6396/5694/25909/7112/5693/140735/5691/7314/996/5515/5516 63 Bluetongue_virus_10 R-HSA-187687 Signalling to ERKs 22/1301 34/10654 8.776210917543757e-13 1.0324015388456018e-11 4.711439545207701e-12 4893/6464/5899/5604/5594/673/57498/6714/5605/10818/5898/53358/5603/6654/2885/5900/5906/3845/3265/7529/5595/25759 22 Bluetongue_virus_10 R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 59/1301 185/10654 9.628638713046993e-13 1.1224737382597125e-11 5.1224905813365224e-12 9136/6138/6144/2091/6203/55813/6194/6234/6191/6128/6132/6147/25879/6129/6222/6152/6136/10528/6125/6224/6146/6154/6141/88745/51602/134430/6134/6160/55272/92856/5394/6205/6165/6142/9790/51077/6156/6235/10199/6124/6207/6139/6233/7311/6223/6188/6135/6161/54881/51202/6187/4691/6168/6208/54512/6157/200916/6122/6230 59 Bluetongue_virus_10 R-HSA-5654688 SHC-mediated cascade:FGFR1 17/1301 21/10654 1.004264193112947e-12 1.1500158105204897e-11 5.248180832197143e-12 4893/6464/8074/2260/2254/2249/26281/2248/2247/2255/27006/6654/2885/2246/2251/3845/3265 17 Bluetongue_virus_10 R-HSA-5654689 PI-3K cascade:FGFR1 17/1301 21/10654 1.004264193112947e-12 1.1500158105204897e-11 5.248180832197143e-12 5295/5290/8074/2260/2254/2249/26281/10818/2248/2247/2255/27006/2885/2246/2251/2549/5781 17 Bluetongue_virus_10 R-HSA-72312 rRNA processing 63/1301 205/10654 1.0493228197455458e-12 1.1910734462725757e-11 5.435550340510168e-12 60528/9136/6138/6144/2091/6203/55651/55813/6194/6234/6191/6128/6132/6147/25879/6129/6222/6152/6136/10528/6125/4839/6224/6146/6154/6141/88745/51602/134430/6134/6160/55272/92856/5394/6205/6165/6142/9790/51077/6156/6235/10199/6124/6207/6139/6233/7311/6223/55505/6188/6135/6161/54881/51202/6187/4691/6168/6208/54512/6157/200916/6122/6230 63 Bluetongue_virus_10 R-HSA-68882 Mitotic Anaphase 62/1301 201/10654 1.3278496890498837e-12 1.4941195631569995e-11 6.818523346059358e-12 4000/5718/5689/4928/81929/5684/55143/5682/5525/7321/5526/8697/5690/9212/5717/79023/10381/57122/64105/332/8881/5528/7316/10213/5501/5519/5711/7444/5708/5692/5686/8243/9126/5529/5702/51529/2010/4001/64682/29945/10393/11004/23592/6233/5527/7514/7311/9184/5518/5347/29882/6396/5694/25909/7112/5693/140735/5691/7314/996/5515/5516 62 Bluetongue_virus_10 R-HSA-6785631 ERBB2 Regulates Cell Motility 14/1301 15/10654 2.0511577133924748e-12 2.2881017940774675e-11 1.0441919030972582e-11 1839/685/2065/2069/2064/1950/51072/145957/3084/2066/9542/10718/387/1956 14 Bluetongue_virus_10 R-HSA-438064 Post NMDA receptor activation events 35/1301 81/10654 2.5656833545502167e-12 2.837601932297419e-11 1.2949602896110407e-11 5923/818/815/3838/4893/2904/817/5594/114/10381/5573/2902/6714/2905/27330/2903/3084/6195/816/2066/1741/2906/1742/1739/88/6196/1740/6197/3845/3265/801/5924/4747/5879/5595 35 Bluetongue_virus_10 R-HSA-388841 Costimulation by the CD28 family 32/1301 70/10654 3.4607312455580464e-12 3.7950730777560274e-11 1.7319092138787372e-11 5295/9402/5290/5525/5526/207/5528/6714/5519/8503/29126/4067/5063/2534/5529/1445/998/5527/2885/7525/79109/2475/3932/5518/5296/5058/5781/5062/5879/253260/5515/5516 32 Bluetongue_virus_10 R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 36/1301 86/10654 3.921688708495077e-12 4.1939381725558926e-11 1.9139342022320476e-11 5718/5689/8945/26271/5684/5682/7321/8697/5690/9212/5717/8881/7316/10213/890/983/6790/5711/5708/5692/5686/5702/51529/64682/29945/10393/6233/7311/9184/5347/29882/5694/5693/5691/7314/996 36 Bluetongue_virus_10 R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 36/1301 86/10654 3.921688708495077e-12 4.1939381725558926e-11 1.9139342022320476e-11 5295/1072/5290/23646/71/5291/5747/4627/10458/4771/5594/2209/3055/6850/10768/10094/6714/10163/4067/3320/55845/2534/998/695/2885/7525/3326/5580/10097/23191/5296/5581/5058/10109/5879/5595 36 Bluetongue_virus_10 R-HSA-453276 Regulation of mitotic cell cycle 36/1301 86/10654 3.921688708495077e-12 4.1939381725558926e-11 1.9139342022320476e-11 5718/5689/8945/26271/5684/5682/7321/8697/5690/9212/5717/8881/7316/10213/890/983/6790/5711/5708/5692/5686/5702/51529/64682/29945/10393/6233/7311/9184/5347/29882/5694/5693/5691/7314/996 36 Bluetongue_virus_10 R-HSA-6806834 Signaling by MET 34/1301 79/10654 6.052493901317626e-12 6.419612383856563e-11 2.9296368236748826e-11 5295/4893/6464/5290/5770/5747/10048/5908/3082/382/3688/7316/6774/4233/6714/1281/3673/5795/2335/64759/6654/200958/6233/2885/7311/5906/57610/23163/3845/2549/3265/5781/7314/5879 34 Bluetongue_virus_10 R-HSA-109581 Apoptosis 56/1301 178/10654 6.8048069754901985e-12 7.158878232751476e-11 3.267006173085154e-11 4000/5718/5689/596/5684/22985/219699/5682/1499/10018/7531/5747/1029/55075/7532/207/10971/5690/5594/10059/5717/7533/2810/118/1829/7534/100506658/7316/10213/6774/54205/5711/10134/999/598/5708/5692/5686/708/5702/7157/4001/6233/5580/6709/6093/7311/5599/5694/5062/5693/140735/5691/7529/7314/5595 56 Bluetongue_virus_10 R-HSA-2682334 EPH-Ephrin signaling 37/1301 92/10654 8.382695154544139e-12 8.74774800804848e-11 3.9920984564509864e-11 1173/1072/71/2042/2904/5747/1947/4627/7074/1949/5921/2902/2041/102/10094/6714/4637/4067/2043/5063/2534/9475/998/1948/4628/2048/7525/10097/6093/387/3265/5058/10109/5062/5663/1969/5879 37 Bluetongue_virus_10 R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 34/1301 80/10654 9.308132686837254e-12 9.635778957413925e-11 4.3973578419500623e-11 5718/5689/8945/26271/5684/5682/7321/8697/5690/5717/8881/7316/10213/890/983/5711/5708/5692/5686/5702/51529/64682/29945/10393/6233/7311/9184/5347/29882/5694/5693/5691/7314/996 34 Bluetongue_virus_10 R-HSA-5654704 SHC-mediated cascade:FGFR3 15/1301 18/10654 1.0607860826247823e-11 1.0808324337924946e-10 4.9324574583713455e-11 4893/6464/8823/8074/8817/2254/2249/26281/2261/2247/6654/2885/2246/3845/3265 15 Bluetongue_virus_10 R-HSA-5654710 PI-3K cascade:FGFR3 15/1301 18/10654 1.0607860826247823e-11 1.0808324337924946e-10 4.9324574583713455e-11 5295/5290/8823/8074/8817/2254/2249/26281/10818/2261/2247/2885/2246/2549/5781 15 Bluetongue_virus_10 R-HSA-442755 Activation of NMDA receptors and postsynaptic events 37/1301 93/10654 1.230920147067981e-11 1.244383336176537e-10 5.678833902180406e-11 5923/818/815/3838/8573/4893/2904/817/5594/114/10381/5573/2902/6714/55327/2905/27330/2903/3084/6195/816/2066/1741/2906/1742/1739/88/6196/1740/6197/3845/3265/801/5924/4747/5879/5595 37 Bluetongue_virus_10 R-HSA-5357801 Programmed Cell Death 56/1301 181/10654 1.4382302930903052e-11 1.442689921906089e-10 6.583820435933589e-11 4000/5718/5689/596/5684/22985/219699/5682/1499/10018/7531/5747/1029/55075/7532/207/10971/5690/5594/10059/5717/7533/2810/118/1829/7534/100506658/7316/10213/6774/54205/5711/10134/999/598/5708/5692/5686/708/5702/7157/4001/6233/5580/6709/6093/7311/5599/5694/5062/5693/140735/5691/7529/7314/5595 56 Bluetongue_virus_10 R-HSA-1236394 Signaling by ERBB4 28/1301 58/10654 1.5188090453457957e-11 1.5117991574441998e-10 6.899205461044464e-11 5295/1839/4893/6464/685/5290/2065/2069/7316/1950/10413/6714/145957/3084/2066/83737/1742/6654/9542/6233/2885/10718/7311/1956/3845/3265/5663/7314 28 Bluetongue_virus_10 R-HSA-5655302 Signaling by FGFR1 in disease 22/1301 38/10654 2.185503077366284e-11 2.1588099100091385e-10 9.851886110104343e-11 5295/8805/4893/5290/9530/8074/2260/2254/6774/2249/26281/10818/2247/6654/2885/2246/2251/9846/11160/3845/2549/3265 22 Bluetongue_virus_10 R-HSA-983705 Signaling by the B Cell Receptor (BCR) 41/1301 112/10654 2.273069780509543e-11 2.228297193923749e-10 1.0168996386490062e-10 5295/5718/5689/8945/5684/4893/4790/5579/5682/5690/5532/5717/7316/10213/10125/5970/4792/6850/10768/25780/5711/4067/5708/5692/5686/2534/5702/695/6654/6233/2885/7311/5293/3845/5694/3265/801/5693/5691/7314/6786 41 Bluetongue_virus_10 R-HSA-8863795 Downregulation of ERBB2 signaling 19/1301 29/10654 2.3563803673003806e-11 2.2925986430727014e-10 1.0462440728575493e-10 1839/685/2065/207/2069/2064/7316/1950/145957/3320/3084/2066/9542/6233/10718/7311/1956/11140/7314 19 Bluetongue_virus_10 R-HSA-389513 CTLA4 inhibitory signaling 16/1301 21/10654 2.509507550289785e-11 2.4054094593148013e-10 1.0977261097174032e-10 5525/5526/207/5528/6714/5519/4067/2534/5529/5527/7525/3932/5518/5781/5515/5516 16 Bluetongue_virus_10 R-HSA-445144 Signal transduction by L1 16/1301 21/10654 2.509507550289785e-11 2.4054094593148013e-10 1.0977261097174032e-10 5604/1459/3674/5594/1460/3678/2260/4684/3688/1457/5605/3690/1956/5058/5879/5595 16 Bluetongue_virus_10 R-HSA-375165 NCAM signaling for neurite out-growth 29/1301 63/10654 2.9032152461009166e-11 2.7623239179813135e-10 1.2606066200175035e-10 5786/2674/9252/4893/6711/6712/5747/5594/2675/4902/2260/4684/2668/57731/6714/6710/1281/64096/2534/6708/6654/2885/6709/51332/9048/3845/5623/3265/5595 29 Bluetongue_virus_10 R-HSA-72766 Translation 76/1301 291/10654 4.224460809764335e-11 3.990111159003686e-10 1.8209162614504742e-10 6138/6144/10352/6203/51253/8891/6194/2107/1965/6234/6191/6128/10952/6132/1938/6147/8666/6129/1915/6222/1983/6152/6136/8668/6125/6727/6224/6146/6154/6141/26986/58477/2935/6134/6160/55699/8661/55157/29927/64963/9669/6729/6205/6165/6142/8663/28972/8894/6156/6235/51263/6124/740/6207/6139/6745/6726/6233/7311/6223/8664/3646/6730/6188/26589/9789/6135/6161/6187/6168/6208/6157/200916/6122/1968/6230 76 Bluetongue_virus_10 R-HSA-76009 Platelet Aggregation (Plug Formation) 22/1301 39/10654 4.438513333891216e-11 4.161910329025531e-10 1.8993180627864014e-10 6464/5770/5747/207/3674/7094/5908/54518/10125/6850/6714/2244/2335/3690/1445/6654/2885/2266/10235/5906/2243/7450 22 Bluetongue_virus_10 R-HSA-5621481 C-type lectin receptors (CLRs) 47/1301 142/10654 4.7733250222742796e-11 4.443656531527279e-10 2.0278949924239843e-10 5718/5689/8945/5684/9252/4893/4790/5682/7321/5690/5532/4582/5717/7316/10213/5970/4792/6850/10768/6714/5711/4067/5708/5692/5686/5063/2534/2033/5702/9040/5894/7189/200958/6233/5580/30835/7311/3845/7334/5694/3265/5058/801/5062/5693/5691/7314 47 Bluetongue_virus_10 R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 32/1301 76/10654 5.12822676590102e-11 4.678199722976209e-10 2.13493048449496e-10 5718/5689/5684/5682/7321/8697/5690/5717/8881/7316/10213/890/983/5711/5708/5692/5686/5702/51529/64682/29945/10393/6233/7311/9184/5347/29882/5694/5693/5691/7314/996 32 Bluetongue_virus_10 R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 31/1301 72/10654 5.133727671272193e-11 4.678199722976209e-10 2.13493048449496e-10 5718/5689/5684/5682/7321/8697/5690/9212/5717/8881/7316/10213/6790/5711/5708/5692/5686/5702/51529/64682/29945/10393/6233/7311/5347/29882/5694/5693/5691/7314/996 31 Bluetongue_virus_10 R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 31/1301 72/10654 5.133727671272193e-11 4.678199722976209e-10 2.13493048449496e-10 5718/5689/5684/5682/7321/8697/5690/5717/8881/7316/10213/890/983/5711/5708/5692/5686/5702/51529/64682/29945/10393/6233/7311/9184/29882/5694/5693/5691/7314/996 31 Bluetongue_virus_10 R-HSA-389356 CD28 co-stimulation 20/1301 33/10654 5.6304414475875123e-11 5.094958904320447e-10 2.3251215694490947e-10 5295/9402/5290/207/6714/8503/4067/5063/2534/998/2885/7525/79109/2475/3932/5296/5058/5062/5879/253260 20 Bluetongue_virus_10 R-HSA-2033519 Activated point mutants of FGFR2 14/1301 17/10654 7.318923144540271e-11 6.57686565905216e-10 3.001400500063664e-10 8823/8074/8817/2254/2263/2249/26281/2248/2247/2255/27006/2246/2251/2252 14 Bluetongue_virus_10 R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 31/1301 73/10654 7.89205831282276e-11 7.042981694339761e-10 3.2141159444599413e-10 5718/5689/5684/5682/7321/8697/5690/5717/8881/7316/10213/890/983/5711/5708/5692/5686/5702/51529/64682/29945/10393/6233/7311/9184/29882/5694/5693/5691/7314/996 31 Bluetongue_virus_10 R-HSA-912631 Regulation of signaling by CBL 16/1301 22/10654 8.15735617561019e-11 7.229875952903826e-10 3.299406499291505e-10 5295/5290/5291/7316/3055/6850/8503/4067/2534/6233/2885/7525/7311/5293/5296/7314 16 Bluetongue_virus_10 R-HSA-8851805 MET activates RAS signaling 11/1301 11/10654 8.674489163524005e-11 7.5843168767568e-10 3.4611581939807735e-10 4893/6464/10048/3082/4233/6654/200958/2885/57610/3845/3265 11 Bluetongue_virus_10 R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 11/1301 11/10654 8.674489163524005e-11 7.5843168767568e-10 3.4611581939807735e-10 627/4893/4915/10817/10818/4909/6654/2885/3845/3265/5781 11 Bluetongue_virus_10 R-HSA-372708 p130Cas linkage to MAPK signaling for integrins 13/1301 15/10654 1.0535580997730202e-10 9.02850451063767e-10 4.1202237293319233e-10 5747/3674/7094/5908/54518/6714/2244/2335/3690/2266/5906/2243/7450 13 Bluetongue_virus_10 R-HSA-5637810 Constitutive Signaling by EGFRvIII 13/1301 15/10654 1.0535580997730202e-10 9.02850451063767e-10 4.1202237293319233e-10 5295/4893/6464/5290/1950/3320/6654/2885/1956/3845/2549/3265/11140 13 Bluetongue_virus_10 R-HSA-5637812 Signaling by EGFRvIII in Cancer 13/1301 15/10654 1.0535580997730202e-10 9.02850451063767e-10 4.1202237293319233e-10 5295/4893/6464/5290/1950/3320/6654/2885/1956/3845/2549/3265/11140 13 Bluetongue_virus_10 R-HSA-2467813 Separation of Sister Chromatids 56/1301 190/10654 1.193004046656748e-10 1.0156231818248894e-9 4.634870292066729e-10 5718/5689/4928/81929/5684/55143/5682/5525/7321/5526/8697/5690/9212/5717/79023/10381/57122/64105/332/8881/5528/7316/10213/5501/5519/5711/5708/5692/5686/8243/9126/5529/5702/51529/64682/29945/10393/11004/6233/5527/7514/7311/9184/5518/5347/29882/6396/5694/25909/5693/140735/5691/7314/996/5515/5516 56 Bluetongue_virus_10 R-HSA-8847993 ERBB2 Activates PTK6 Signaling 12/1301 13/10654 1.2140048909540492e-10 1.0267466201925096e-9 4.685632912454226e-10 1839/685/2065/2069/2064/1950/145957/3084/2066/9542/10718/1956 12 Bluetongue_virus_10 R-HSA-68886 M Phase 93/1301 395/10654 1.386233102328428e-10 1.164795866501939e-9 5.315630693139086e-10 4000/5718/23165/5689/4928/26271/81929/5684/55706/55143/5579/5682/9631/5525/7531/10142/1459/7321/5526/7532/8697/5690/5578/9212/5594/5717/5861/121441/1460/79023/9133/10381/57122/64105/5116/332/8881/5528/7316/10213/5501/26003/1457/983/8548/9688/9702/5519/5711/7444/5708/3320/5692/5686/8243/9126/10426/5529/9918/5702/10540/51529/8086/2010/4001/64682/29945/10393/79648/11004/23592/6233/5527/7514/7311/9184/5518/5347/29882/6396/5694/25909/27229/7112/5693/140735/10806/5691/7314/996/5595/5515/5516 93 Bluetongue_virus_10 R-HSA-69620 Cell Cycle Checkpoints 75/1301 293/10654 1.5836270164160413e-10 1.3220731349950691e-9 6.033376952186074e-10 5718/6118/5689/4928/81929/5684/55143/5682/5525/7531/1029/7486/7321/5526/7532/10971/8697/5690/9212/5717/7533/2810/545/79023/9133/57122/64105/7534/332/580/8881/5528/7316/10213/5501/890/983/5519/5711/4683/5708/5692/5985/5686/5529/5702/7157/51529/64682/29945/10393/11004/6233/5527/7514/23595/7311/9184/5518/5347/29882/6396/7334/5694/25909/5810/5693/140735/4999/5691/7529/7314/996/5515/5516 75 Bluetongue_virus_10 R-HSA-195258 RHO GTPase Effectors 81/1301 327/10654 1.661729154293517e-10 1.3783830292665456e-9 6.290351252082748e-10 85415/3831/4928/81929/5590/1072/27035/71/55143/5579/1495/1499/5525/7531/5747/1856/5526/4627/7532/10971/10458/4771/5578/9212/5594/1080/7533/2810/79023/10381/57122/64105/7534/332/5528/3688/5501/10094/6279/6714/5519/4637/10163/999/55845/5063/9475/3895/5529/998/4628/695/10788/11004/1742/5527/1855/2885/5580/10097/23191/7514/6093/9184/8826/5518/5347/387/5300/6396/25909/5058/801/10109/5062/140735/7529/5879/5595/5515/5516 81 Bluetongue_virus_10 R-HSA-8878159 Transcriptional regulation by RUNX3 36/1301 96/10654 1.714643296620432e-10 1.4132155578514898e-9 6.449312030868673e-10 5718/5689/8463/6046/5684/5682/1499/10018/1029/864/5690/5717/7316/10213/865/10413/6714/4609/4089/22938/5711/5708/5692/5686/2033/595/5702/7157/6233/7311/3845/5694/4851/5693/5691/7314 36 Bluetongue_virus_10 R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 28/1301 63/10654 1.7818619705502644e-010 1.4593223986658493e-9 6.65972395388873e-10 5718/5689/5684/5682/7321/8697/5690/5717/8881/7316/10213/5711/5708/5692/5686/5702/51529/64682/29945/10393/6233/7311/29882/5694/5693/5691/7314/996 28 Bluetongue_virus_10 R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 31/1301 75/10654 1.811111684071212e-10 1.4739487542063827e-9 6.726472391684542e-10 5718/5689/5684/5682/7321/8697/5690/5717/8881/7316/10213/890/983/5711/5708/5692/5686/5702/51529/64682/29945/10393/6233/7311/9184/29882/5694/5693/5691/7314/996 31 Bluetongue_virus_10 R-HSA-438066 Unblocking of NMDA receptors, glutamate binding and activation 16/1301 23/10654 2.3762398960452773e-10 1.9098474692438437e-9 8.715727895922856e-10 818/815/2904/817/2902/2905/2903/816/1741/2906/1742/1739/88/1740/801/4747 16 Bluetongue_virus_10 R-HSA-9617324 Negative regulation of NMDA receptor-mediated neuronal transmission 16/1301 23/10654 2.3762398960452773e-10 1.9098474692438437e-9 8.715727895922856e-10 818/815/2904/817/2902/2905/2903/816/1741/2906/1742/1739/88/1740/801/4747 16 Bluetongue_virus_10 R-HSA-2871796 FCERI mediated MAPK activation 19/1301 32/10654 2.840354397846384e-10 2.2687769079093955e-9 1.035372850676947e-9 3725/9402/5601/4893/6464/5594/6850/4067/5602/5609/6654/2885/3845/5599/3265/5058/5062/5879/5595 19 Bluetongue_virus_10 R-HSA-210993 Tie2 Signaling 14/1301 18/10654 2.9222402861244574e-10 2.305718859905517e-9 1.0522315792784473e-9 5295/4893/6464/5290/5291/7010/6654/2885/5296/3845/3265/5781/284/9046 14 Bluetongue_virus_10 R-HSA-5654221 Phospholipase C-mediated cascade; FGFR2 14/1301 18/10654 2.9222402861244574e-10 2.305718859905517e-9 1.0522315792784473e-9 8823/8074/8817/2254/2263/2249/26281/2248/2247/2255/27006/2246/2251/2252 14 Bluetongue_virus_10 R-HSA-177929 Signaling by EGFR 24/1301 49/10654 2.975430556619399e-10 2.3334588728881835e-9 1.0648909360532585e-9 5295/1839/4893/6464/685/5290/2069/7316/1950/102/6714/55824/1445/998/6654/6233/2885/7311/1956/3845/2549/3265/5781/7314 24 Bluetongue_virus_10 R-HSA-1295596 Spry regulation of FGF signaling 13/1301 16/10654 4.988145762509984e-10 3.888349769089108e-9 1.7744767106963226e-9 5594/7316/673/6714/6233/2885/7311/5518/5781/7314/5595/5515/5516 13 Bluetongue_virus_10 R-HSA-195253 Degradation of beta-catenin by the destruction complex 32/1301 82/10654 5.408968526519504e-10 4.191140882225293e-9 1.9126576384351986e-9 5718/5689/8945/5684/5682/1499/5525/5526/10023/1452/5690/5717/5528/7316/10213/5519/5711/5708/5692/5686/5529/5702/6233/5527/7311/5518/5694/5693/5691/7314/5515/5516 32 Bluetongue_virus_10 R-HSA-1433557 Signaling by SCF-KIT 22/1301 43/10654 5.622394022135915e-10 4.33058206228802e-9 1.9762926356004064e-9 5295/9402/4893/5290/3815/5578/6774/6714/8503/4067/3717/2534/6654/2885/7525/9846/3932/5296/3845/3265/5781/5879 22 Bluetongue_virus_10 R-HSA-1839126 FGFR2 mutant receptor activation 19/1301 33/10654 5.930989741322444e-10 4.5412430327048764e-9 2.072429302324442e-9 8823/5430/5436/8074/8817/5431/2254/2263/2249/26281/2248/5437/2247/2255/27006/2246/2251/2252/5432 19 Bluetongue_virus_10 R-HSA-1250342 PI3K events in ERBB4 signaling 10/1301 10/10654 7.151918098880677e-10 5.388475837940168e-9 2.4590701578820745e-9 5295/1839/685/5290/2069/145957/3084/2066/9542/10718 10 Bluetongue_virus_10 R-HSA-8853334 Signaling by FGFR3 fusions in cancer 10/1301 10/10654 7.151918098880677e-10 5.388475837940168e-9 2.4590701578820745e-9 5295/4893/5290/10818/2261/6654/2885/3845/2549/3265 10 Bluetongue_virus_10 R-HSA-2262752 Cellular responses to stress 105/1301 479/10654 7.162425379642264e-10 5.388475837940168e-9 2.4590701578820745e-9 5718/23165/818/6118/5689/3725/4928/815/25913/81929/1019/5684/5601/4790/55706/5682/9631/9448/7531/1029/1915/7321/2146/817/9550/7422/8697/5690/9114/5594/9530/5717/50488/545/79023/10381/57122/3313/8881/7316/10213/890/527/6774/5970/9532/54205/832/9688/6647/5711/4683/245972/144577/5708/3320/5602/5692/5686/2033/6195/6767/816/5702/10540/7157/51529/8086/4001/64682/29945/10393/5609/10542/6233/3326/2475/55004/6196/7311/538/57634/10587/6197/29882/5599/6396/54583/5694/3312/405/3569/64121/57521/5693/10641/140735/5691/51382/7314/51164/996/51182/5595/23043 105 Bluetongue_virus_10 R-HSA-190322 FGFR4 ligand binding and activation 12/1301 14/10654 7.548527555763516e-10 5.646124079282076e-9 2.5766498075955782e-9 8823/8074/8817/2254/152831/2249/26281/2247/9965/2264/2246/2251 12 Bluetongue_virus_10 R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 24/1301 51/10654 8.467241100842192e-10 6.296902289936665e-9 2.8736371794146827e-9 6203/6194/1965/6234/6191/8666/6222/8668/6224/8661/6205/8663/8894/6235/6207/6233/6223/8664/3646/6188/6187/6208/1968/6230 24 Bluetongue_virus_10 R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 33/1301 88/10654 9.876023455869458e-10 7.3026139153686165e-9 3.33260099774001e-9 5718/5689/5684/5682/3842/207/5690/5578/5717/3315/26986/7534/8125/7316/10213/8741/5711/5708/5692/5686/5702/6233/5580/7514/7311/5694/3312/5693/54512/5691/7529/7314/1994 33 Bluetongue_virus_10 R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 28/1301 67/10654 1.0173232847309182e-9 7.479638241146637e-9 3.4133873369261076e-9 5718/5689/5684/5682/7321/8697/5690/5717/8881/7316/10213/5711/5708/5692/5686/5702/51529/64682/29945/10393/6233/7311/29882/5694/5693/5691/7314/996 28 Bluetongue_virus_10 R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 64/1301 244/10654 1.2422654815792578e-9 9.081873068720675e-9 4.144578859149353e-9 10450/10921/23165/4928/81929/6633/51340/55706/24148/9631/27339/9129/5430/4904/5436/9128/57703/29894/79023/57122/3183/5431/81608/10594/9785/11338/3185/4116/3190/10978/24144/9688/22938/988/10236/9984/5437/10250/10569/23658/84844/10482/10949/3181/1660/8086/9939/10285/6638/6636/10286/23524/9775/6396/79228/3312/2733/6426/57461/10907/5432/26121/10992/1994 64 Bluetongue_virus_10 R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 29/1301 72/10654 1.4538061671398552e-9 1.0568680788084115e-8 4.823094380635475e-9 5718/5689/5684/5682/7321/8697/5690/5717/8881/7316/10213/890/5711/5708/5692/5686/5702/51529/64682/29945/10393/6233/7311/29882/5694/5693/5691/7314/996 29 Bluetongue_virus_10 R-HSA-180292 GAB1 signalosome 13/1301 17/10654 1.8820969468691878e-9 1.3605773459490107e-8 6.20909372063284e-9 5295/1839/685/5290/2069/1950/6714/55824/1445/2885/1956/2549/5781 13 Bluetongue_virus_10 R-HSA-190241 FGFR2 ligand binding and activation 14/1301 20/10654 2.9145733639285792e-9 2.0947365660962046e-8 9.559482742861554e-9 8823/8074/8817/2254/2263/2249/26281/2248/2247/2255/27006/2246/2251/2252 14 Bluetongue_virus_10 R-HSA-202403 TCR signaling 39/1301 119/10654 2.930041100953733e-9 2.0947365660962046e-8 9.559482742861554e-9 5295/5718/5689/8945/9402/5684/5290/4790/5682/5291/7321/5690/5717/7316/10213/5970/4792/5711/5795/55824/5708/5692/5686/5063/5728/1445/5702/7189/6233/7311/3932/5296/7334/5694/5058/5062/5693/5691/7314 39 Bluetongue_virus_10 R-HSA-162909 Host Interactions of HIV factors 41/1301 129/10654 3.2378784589543814e-9 2.3020960032345987e-8 1.0505782622749614e-8 5718/23165/5689/8945/1173/4928/81929/5684/55706/5682/9631/5690/5717/4869/79023/57122/7316/10213/3055/9688/5711/5708/5692/5686/2534/5702/5902/8086/6233/7514/7311/3932/6396/375/5694/55690/5062/5693/5691/7314/5879 41 Bluetongue_virus_10 R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission 56/1301 206/10654 3.350129595659916e-9 2.357921552248083e-8 1.0760546577818066e-8 5923/818/1173/815/3838/8573/4893/5579/5331/2904/59345/2770/817/5578/5594/2036/112/114/10381/5573/2902/80852/6714/55327/2905/27330/2903/23236/3084/6195/2783/2784/9495/2782/816/2066/4905/1741/2906/2771/1742/1739/88/6196/1740/6197/3845/115/3265/801/5924/4747/2773/5879/5595/2787 56 Bluetongue_virus_10 R-HSA-5654228 Phospholipase C-mediated cascade; FGFR4 12/1301 15/10654 3.352840537972545e-9 2.357921552248083e-8 1.0760546577818066e-8 8823/8074/8817/2254/152831/2249/26281/2247/9965/2264/2246/2251 12 Bluetongue_virus_10 R-HSA-194315 Signaling by Rho GTPases 99/1301 455/10654 3.4207004937279933e-9 2.392641318315688e-8 1.0918992756650951e-8 85415/3831/4928/9743/445328/81929/5590/1072/27035/71/55143/5579/1495/1499/5525/392/7531/5747/55789/1856/57580/5526/4627/7532/2909/10928/10971/10458/4771/5578/9212/5594/7074/9459/1080/7533/2810/79023/10381/57122/64105/7534/332/5528/3688/5501/10094/6279/6714/5519/4637/10163/999/1123/55845/5063/9475/3895/57514/57584/5529/998/4628/695/10788/2/11004/1742/6654/5527/1855/2885/5580/10097/23191/7514/6093/9184/8826/5518/26084/5347/387/6655/5296/5300/6396/25909/5058/801/10109/5062/5924/140735/7529/5879/5595/5515/5516 99 Bluetongue_virus_10 R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 31/1301 83/10654 3.5574557797721924e-9 2.4749181607662456e-8 1.1294469114047541e-8 5718/5689/8945/5684/4893/4790/5579/5682/5690/5532/5717/7316/10213/10125/5970/4792/25780/5711/5708/5692/5686/5702/6233/7311/3845/5694/3265/801/5693/5691/7314 31 Bluetongue_virus_10 R-HSA-72649 Translation initiation complex formation 25/1301 58/10654 3.700468929304002e-9 2.5470248907017973e-8 1.1623533422953783e-8 6203/6194/1965/6234/6191/8666/6222/8668/6224/26986/8661/6205/8663/8894/6235/6207/6233/6223/8664/3646/6188/6187/6208/1968/6230 25 Bluetongue_virus_10 R-HSA-72702 Ribosomal scanning and start codon recognition 25/1301 58/10654 3.700468929304002e-9 2.5470248907017973e-8 1.1623533422953783e-8 6203/6194/1965/6234/6191/8666/6222/1983/8668/6224/8661/6205/8663/8894/6235/6207/6233/6223/8664/3646/6188/6187/6208/1968/6230 25 Bluetongue_virus_10 R-HSA-8953897 Cellular responses to external stimuli 105/1301 493/10654 3.866559164803443e-9 2.647263258865426e-8 1.2080978509912179e-8 5718/23165/818/6118/5689/3725/4928/815/25913/81929/1019/5684/5601/4790/55706/5682/9631/9448/7531/1029/1915/7321/2146/817/9550/7422/8697/5690/9114/5594/9530/5717/50488/545/79023/10381/57122/3313/8881/7316/10213/890/527/6774/5970/9532/54205/832/9688/6647/5711/4683/245972/144577/5708/3320/5602/5692/5686/2033/6195/6767/816/5702/10540/7157/51529/8086/4001/64682/29945/10393/5609/10542/6233/3326/2475/55004/6196/7311/538/57634/10587/6197/29882/5599/6396/54583/5694/3312/405/3569/64121/57521/5693/10641/140735/5691/51382/7314/51164/996/51182/5595/23043 105 Bluetongue_virus_10 R-HSA-8941858 Regulation of RUNX3 expression and activity 24/1301 55/10654 5.634314855861265e-9 3.8372649597286725e-8 1.7511637862261327e-8 5718/5689/5684/5682/1029/864/5690/5717/7316/10213/865/6714/5711/5708/5692/5686/2033/5702/6233/7311/5694/5693/5691/7314 24 Bluetongue_virus_10 R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 25/1301 59/10654 5.6835075400501e-9 3.850501966923994e-8 1.7572045907787856e-8 6203/6194/1965/6234/6191/8666/6222/8668/6224/26986/8661/6205/8663/8894/6235/6207/6233/6223/8664/3646/6188/6187/6208/1968/6230 25 Bluetongue_virus_10 R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 13/1301 18/10654 6.0157665343367105e-9 4.054375987204012e-8 1.85024398342264e-8 1839/4893/5578/5594/6195/6654/2885/6196/1956/6197/3845/3265/5595 13 Bluetongue_virus_10 R-HSA-5655291 Signaling by FGFR4 in disease 10/1301 11/10654 6.999660992416329e-9 4.6930369555371657e-8 2.1417015635372573e-8 5295/4893/5290/10818/2264/6654/2885/3845/2549/3265 10 Bluetongue_virus_10 R-HSA-5621575 CD209 (DC-SIGN) signaling 14/1301 21/10654 7.759570773858777e-9 5.1757137017387924e-8 2.361974608863144e-8 9252/4893/4790/5970/4067/5063/2534/2033/5894/30835/3845/3265/5058/5062 14 Bluetongue_virus_10 R-HSA-162906 HIV Infection 60/1301 233/10654 8.718658465650484e-9 5.785612335667552e-8 2.6403062883832236e-8 5718/23165/5689/8945/1173/4928/6917/81929/5684/55706/79643/5682/9631/5430/5436/5690/7520/5717/4869/79023/57122/91782/5431/7316/10213/6872/3055/9688/5711/23327/5437/89853/83860/5708/5692/5686/2534/2068/5702/2071/5902/8086/6233/7514/7311/3932/93343/11198/6396/375/5694/55690/2547/2961/5062/5432/5693/5691/7314/5879 60 Bluetongue_virus_10 R-HSA-2871837 FCERI mediated NF-kB activation 30/1301 82/10654 1.115258184112475e-8 7.362980052252768e-8 3.360149523561217e-8 5718/5689/8945/5684/4790/5682/7321/5690/5717/7316/10213/10125/5970/4792/5711/4067/5708/5692/5686/5702/7189/6233/10235/7311/115727/7334/5694/5693/5691/7314 30 Bluetongue_virus_10 R-HSA-3858494 Beta-catenin independent WNT signaling 43/1301 146/10654 1.7601344422005017e-8 1.1561492224403295e-7 5.276171103790978e-8 5718/5689/1173/815/5684/5579/5682/5331/1499/59345/1856/5690/5578/5532/5717/409/7316/10213/5711/4919/23236/5708/5692/5686/2783/2784/2782/5702/23513/57216/6233/1855/7311/387/3845/5694/801/5693/5691/4920/7314/5879/2787 43 Bluetongue_virus_10 R-HSA-9006335 Signaling by Erythropoietin 15/1301 25/10654 1.8352488879407104e-8 1.1994000308056965e-7 5.473549314910891e-8 5295/4893/6464/5290/5291/4067/3717/5294/6654/2885/8660/5293/3845/2549/3265 15 Bluetongue_virus_10 R-HSA-72163 mRNA Splicing - Major Pathway 50/1301 183/10654 1.9431455240943836e-8 1.2635328181799659e-7 5.7662239567148873e-8 10450/10921/6633/51340/24148/27339/9129/5430/4904/5436/9128/57703/29894/3183/5431/81608/10594/9785/11338/3185/4116/3190/10978/24144/22938/988/10236/5437/10250/10569/23658/84844/10949/3181/1660/9939/10285/6638/6636/10286/23524/9775/3312/6426/57461/10907/5432/26121/10992/1994 50 Bluetongue_virus_10 R-HSA-180336 SHC1 events in EGFR signaling 11/1301 14/10654 2.21832171003017e-8 1.43525414638952e-7 6.549886733299608e-8 1839/4893/6464/685/2069/1950/6654/2885/1956/3845/3265 11 Bluetongue_virus_10 R-HSA-3371556 Cellular response to heat stress 31/1301 89/10654 2.4477588896130666e-8 1.575820897094183e-7 7.191373328478296e-8 23165/818/6118/4928/815/81929/55706/9631/7531/1915/817/5594/9530/545/79023/57122/3313/9532/9688/3320/2033/6767/816/8086/3326/2475/6396/3312/57521/51182/5595 31 Bluetongue_virus_10 R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 30/1301 85/10654 2.9076178531093323e-8 1.844341912707586e-7 8.416788522158595e-8 3725/8945/5601/351/9252/4790/5604/5594/246330/5528/7316/5970/4792/177/5519/5602/6195/7189/5609/6233/6196/7311/5518/6197/5599/7334/7314/5595/5515/5516 30 Bluetongue_virus_10 R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 30/1301 85/10654 2.9076178531093323e-8 1.844341912707586e-7 8.416788522158595e-8 3725/8945/5601/351/9252/4790/5604/5594/246330/5528/7316/5970/4792/177/5519/5602/6195/7189/5609/6233/6196/7311/5518/6197/5599/7334/7314/5595/5515/5516 30 Bluetongue_virus_10 R-HSA-975871 MyD88 cascade initiated on plasma membrane 30/1301 85/10654 2.9076178531093323e-8 1.844341912707586e-7 8.416788522158595e-8 3725/8945/5601/351/9252/4790/5604/5594/246330/5528/7316/5970/4792/177/5519/5602/6195/7189/5609/6233/6196/7311/5518/6197/5599/7334/7314/5595/5515/5516 30 Bluetongue_virus_10 R-HSA-186763 Downstream signal transduction 16/1301 29/10654 3.1976017415251924e-8 2.0183886114798045e-7 9.211063296511596e-8 5295/4893/5290/5291/5921/6774/6714/5159/6654/2885/5155/5296/3845/3265/5781/5156 16 Bluetongue_virus_10 R-HSA-69052 Switching of origins to a post-replicative state 31/1301 90/10654 3.303257911850952e-8 2.0749590960850157e-7 9.469226819358122e-8 5718/5689/5684/5682/7321/8697/5690/5717/8881/7316/10213/890/5711/5708/5692/5686/5702/51529/64682/29945/10393/6233/23595/7311/29882/5694/5693/4999/5691/7314/996 31 Bluetongue_virus_10 R-HSA-453279 Mitotic G1-G1/S phases 43/1301 149/10654 3.407394485753802e-8 2.1300330746692852e-7 9.720560928084837e-8 5718/6118/5689/26271/1019/5684/5682/1029/207/5690/5717/286826/7316/10213/5422/890/983/5426/6714/4609/5519/5711/5427/4067/3717/5708/5692/5686/595/5702/6233/7298/23595/7311/5518/1719/5694/5693/4999/5691/7314/5515/5516 43 Bluetongue_virus_10 R-HSA-196299 Beta-catenin phosphorylation cascade 12/1301 17/10654 3.599368996618046e-8 2.2285088428821777e-7 1.0169962261912486e-7 1499/5525/5526/10023/1452/5528/5519/5529/5527/5518/5515/5516 12 Bluetongue_virus_10 R-HSA-9034015 Signaling by NTRK3 (TRKC) 12/1301 17/10654 3.599368996618046e-8 2.2285088428821777e-7 1.0169962261912486e-7 5295/4908/4893/6464/5290/3667/6714/6654/2885/3845/3265/4916 12 Bluetongue_virus_10 R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 32/1301 95/10654 3.659241211911606e-8 2.244103378300293e-7 1.024112905902924e-7 3725/8945/5601/351/9252/4790/5604/5594/246330/5528/7316/5970/4792/59307/177/5519/5602/6195/695/7189/5609/6233/6196/7311/5518/6197/5599/7334/7314/5595/5515/5516 32 Bluetongue_virus_10 R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 32/1301 95/10654 3.659241211911606e-8 2.244103378300293e-7 1.024112905902924e-7 3725/8945/5601/351/9252/4790/5604/5594/246330/5528/7316/5970/4792/59307/177/5519/5602/6195/695/7189/5609/6233/6196/7311/5518/6197/5599/7334/7314/5595/5515/5516 32 Bluetongue_virus_10 R-HSA-450294 MAP kinase activation 25/1301 64/10654 4.0895549206717725e-8 2.496171729881733e-7 1.1391461323221772e-7 3725/8945/5601/9252/4790/5604/5594/5528/7316/5519/5602/6195/7189/5609/6233/6196/7311/5518/6197/5599/7334/7314/5595/5515/5516 25 Bluetongue_virus_10 R-HSA-167044 Signalling to RAS 13/1301 20/10654 4.291589514746713e-8 2.597453267005999e-7 1.1853666987638215e-7 4893/6464/5899/6714/5898/53358/5603/6654/2885/5900/3845/3265/25759 13 Bluetongue_virus_10 R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 14/1301 23/10654 4.295633687320586e-8 2.597453267005999e-7 1.1853666987638215e-7 7321/8697/8881/7316/983/51529/64682/29945/10393/6233/7311/29882/7314/996 14 Bluetongue_virus_10 R-HSA-111885 Opioid Signalling 31/1301 91/10654 4.432234802140475e-8 2.6675868995208255e-7 1.2173726922892569e-7 818/815/3838/5331/59345/2770/817/5578/5532/5594/112/114/2779/5573/5528/10768/5519/23236/2783/2784/2782/816/2771/5580/5518/115/801/2773/5515/2787/5516 31 Bluetongue_virus_10 R-HSA-112315 Transmission across Chemical Synapses 65/1301 272/10654 4.8846775614843996e-8 2.9262836872966727e-7 1.3354308537976358e-7 5923/818/1173/6507/815/3838/8573/4893/9254/5579/5331/2904/59345/2770/817/5578/5594/2036/112/114/10381/5573/2902/80852/6714/54407/55327/2905/8500/81539/27330/2903/23236/3084/6195/2783/2784/9495/2782/816/2066/4905/1741/2906/2771/10550/1742/1739/22999/6844/88/6196/1740/6197/3845/115/3265/3312/801/5924/4747/2773/5879/5595/2787 65 Bluetongue_virus_10 R-HSA-195721 Signaling by WNT 75/1301 331/10654 5.0532894739787094e-8 3.0133440457734793e-7 1.375161481883122e-7 5718/5689/8945/1173/815/5684/79971/7015/5579/5682/5331/1499/5525/59345/864/1459/1856/5526/10023/207/1452/5690/5578/5532/5717/5929/409/79577/1460/7534/8452/5528/7316/10213/1457/9559/4609/5519/5711/4919/23236/5708/5692/5686/2033/2783/8724/2784/5529/2782/5702/23513/57216/6233/5527/1855/7514/4040/7311/79412/5518/387/8607/3845/6659/5694/801/5693/5691/4920/7314/5879/5515/2787/5516 75 Bluetongue_virus_10 R-HSA-5607764 CLEC7A (Dectin-1) signaling 33/1301 101/10654 5.2114252331838975e-8 3.09338727144035e-7 1.4116897903506358e-7 5718/5689/8945/5684/4790/5682/7321/5690/5532/5717/7316/10213/5970/4792/6850/10768/6714/5711/5708/5692/5686/5702/9040/7189/6233/5580/7311/7334/5694/801/5693/5691/7314 33 Bluetongue_virus_10 R-HSA-69206 G1/S Transition 39/1301 131/10654 5.857196081581491e-8 3.4608272737746343e-7 1.57937370909263e-7 5718/6118/5689/26271/1019/5684/5682/207/5690/5717/286826/7316/10213/5422/890/983/5426/4609/5519/5711/5427/5708/5692/5686/595/5702/6233/7298/23595/7311/5518/1719/5694/5693/4999/5691/7314/5515/5516 39 Bluetongue_virus_10 R-HSA-4086400 PCP/CE pathway 31/1301 92/10654 5.913951813069247e-8 3.47847893005073e-7 1.5874291708764824e-7 5718/5689/1173/5684/5579/5682/1856/5690/5578/5717/409/7316/10213/5711/4919/5708/5692/5686/5702/23513/57216/6233/1855/7311/387/5694/5693/5691/4920/7314/5879 31 Bluetongue_virus_10 R-HSA-2424491 DAP12 signaling 16/1301 30/10654 6.077008248919827e-8 3.558212069729527e-7 1.6238159693469982e-7 5295/9402/4893/6464/5290/5291/6850/2534/695/6654/2885/3932/5296/3845/3265/5879 16 Bluetongue_virus_10 R-HSA-1236974 ER-Phagosome pathway 29/1301 83/10654 6.376432440190989e-8 3.71671332324646e-7 1.6961491697236348e-7 5718/8773/5689/5684/10952/5682/3107/5690/5717/811/9554/7316/10213/29927/5711/9341/5708/5692/5686/5702/695/6233/7311/5694/8673/3105/5693/5691/7314 29 Bluetongue_virus_10 R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 11/1301 15/10654 7.396675264670624e-8 4.197937628282363e-7 1.915759382954857e-7 1499/5525/5526/1452/5528/5519/5529/5527/5518/5515/5516 11 Bluetongue_virus_10 R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 11/1301 15/10654 7.396675264670624e-8 4.197937628282363e-7 1.915759382954857e-7 1499/5525/5526/1452/5528/5519/5529/5527/5518/5515/5516 11 Bluetongue_virus_10 R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 11/1301 15/10654 7.396675264670624e-8 4.197937628282363e-7 1.915759382954857e-7 1499/5525/5526/1452/5528/5519/5529/5527/5518/5515/5516 11 Bluetongue_virus_10 R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 11/1301 15/10654 7.396675264670624e-8 4.197937628282363e-7 1.915759382954857e-7 1499/5525/5526/1452/5528/5519/5529/5527/5518/5515/5516 11 Bluetongue_virus_10 R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 11/1301 15/10654 7.396675264670624e-8 4.197937628282363e-7 1.915759382954857e-7 1499/5525/5526/1452/5528/5519/5529/5527/5518/5515/5516 11 Bluetongue_virus_10 R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 11/1301 15/10654 7.396675264670624e-8 4.197937628282363e-7 1.915759382954857e-7 1499/5525/5526/1452/5528/5519/5529/5527/5518/5515/5516 11 Bluetongue_virus_10 R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 32/1301 98/10654 8.420308182953184e-8 4.7168306444768047e-7 2.1525599866196112e-7 3725/8945/5601/351/9252/4790/5604/5594/246330/5528/7316/5970/4792/59307/177/5519/5602/6195/695/7189/5609/6233/6196/7311/5518/6197/5599/7334/7314/5595/5515/5516 32 Bluetongue_virus_10 R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 32/1301 98/10654 8.420308182953184e-8 4.7168306444768047e-7 2.1525599866196112e-7 3725/8945/5601/351/9252/4790/5604/5594/246330/5528/7316/5970/4792/59307/177/5519/5602/6195/695/7189/5609/6233/6196/7311/5518/6197/5599/7334/7314/5595/5515/5516 32 Bluetongue_virus_10 R-HSA-202424 Downstream TCR signaling 32/1301 98/10654 8.420308182953184e-8 4.7168306444768047e-7 2.1525599866196112e-7 5295/5718/5689/8945/5684/5290/4790/5682/5291/7321/5690/5717/7316/10213/5970/4792/5711/5708/5692/5686/5728/5702/7189/6233/7311/3932/5296/7334/5694/5693/5691/7314 32 Bluetongue_virus_10 R-HSA-72172 mRNA Splicing 50/1301 191/10654 8.675064875235945e-8 4.838592219204877e-7 2.2081267672447215e-7 10450/10921/6633/51340/24148/27339/9129/5430/4904/5436/9128/57703/29894/3183/5431/81608/10594/9785/11338/3185/4116/3190/10978/24144/22938/988/10236/5437/10250/10569/23658/84844/10949/3181/1660/9939/10285/6638/6636/10286/23524/9775/3312/6426/57461/10907/5432/26121/10992/1994 50 Bluetongue_virus_10 R-HSA-163685 Integration of energy metabolism 34/1301 108/10654 9.196458300729274e-8 5.107389288044499e-7 2.3307942655112368e-7 5313/9254/5331/59345/2770/5578/112/114/4082/5573/5528/2778/10768/5519/23236/6794/2783/2784/9495/2782/2776/2771/7086/6844/8826/5906/2182/5518/115/31/2181/5515/2787/5516 34 Bluetongue_virus_10 R-HSA-5218921 VEGFR2 mediated cell proliferation 13/1301 21/10654 1.0004492225458073e-7 5.532398692197755e-7 2.524750399677004e-7 5590/4893/5579/7422/5578/5921/10768/6714/5580/3845/3265/801/8877 13 Bluetongue_virus_10 R-HSA-9604323 Negative regulation of NOTCH4 signaling 22/1301 54/10654 1.094958783569744e-7 6.029262408252122e-7 2.751497771926658e-7 5718/5689/5684/5682/207/5690/5717/7534/7316/10213/5711/5708/5692/5686/55294/5702/6233/7311/5694/5693/5691/7314 22 Bluetongue_virus_10 R-HSA-1236975 Antigen processing-Cross presentation 32/1301 99/10654 1.1007024363291193e-7 6.035207426313052e-7 2.754210824177681e-7 5718/8773/5689/5684/10952/5682/3107/5690/5717/811/2209/9554/7316/10213/29927/5711/9341/5708/5692/5686/5702/695/9902/6233/4012/7311/5694/8673/3105/5693/5691/7314 32 Bluetongue_virus_10 R-HSA-1839124 FGFR1 mutant receptor activation 16/1301 31/10654 1.1139278085621381e-7 6.081951832402561e-7 2.7755429740322433e-7 5295/8805/5290/9530/8074/2260/2254/6774/2249/26281/2247/2885/2246/2251/9846/11160 16 Bluetongue_virus_10 R-HSA-69239 Synthesis of DNA 36/1301 119/10654 1.2040378321452222e-7 6.546323339478645e-7 2.987462290285138e-7 5718/6118/5689/5684/5682/7321/8697/5690/5717/8881/7316/10213/5422/890/5426/5711/5427/5708/5692/5985/5686/5702/51529/64682/29945/10393/6233/23595/7311/29882/5694/5693/4999/5691/7314/996 36 Bluetongue_virus_10 R-HSA-179812 GRB2 events in EGFR signaling 10/1301 13/10654 1.4412120940167275e-7 7.738292322230894e-7 3.5314260089250237e-7 1839/4893/685/2069/1950/6654/2885/1956/3845/3265 10 Bluetongue_virus_10 R-HSA-190375 FGFR2c ligand binding and activation 10/1301 13/10654 1.4412120940167275e-7 7.738292322230894e-7 3.5314260089250237e-7 8823/8074/8817/2254/2263/2249/26281/2247/2246/2251 10 Bluetongue_virus_10 R-HSA-5658623 FGFRL1 modulation of FGFR1 signaling 10/1301 13/10654 1.4412120940167275e-7 7.738292322230894e-7 3.5314260089250237e-7 8074/8817/2249/2248/2247/2255/27006/53834/200734/161742 10 Bluetongue_virus_10 R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 27/1301 77/10654 1.6613705539687553e-7 8.883526846427972e-7 4.0540621173400254e-7 5718/5689/5684/5682/63943/5690/5717/9133/10381/7316/10213/983/5711/5708/3320/5692/5686/5702/7157/6233/3326/7311/5347/5694/5693/5691/7314 27 Bluetongue_virus_10 R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 14/1301 25/10654 1.84620036223737e-7 9.831206867222866e-7 4.486542790622329e-7 7321/8697/8881/7316/51529/64682/29945/10393/6233/7311/9184/29882/7314/996 14 Bluetongue_virus_10 R-HSA-9013694 Signaling by NOTCH4 28/1301 82/10654 1.870714832072089e-7 9.920922101234768e-7 4.5274849904764543e-7 5718/5689/5684/5682/207/5690/5717/7534/7316/10213/102/22938/5711/5708/5692/5686/2033/55294/4853/5702/6233/7311/5694/4851/5693/5663/5691/7314 28 Bluetongue_virus_10 R-HSA-8878166 Transcriptional regulation by RUNX2 36/1301 121/10654 1.9155213031342174e-7 1.0117079862268072e-6 4.6170030120657195e-7 5718/5689/7291/1019/5684/5682/207/5690/5594/5717/100526737/3958/3678/2737/7316/10213/865/983/10413/6714/4089/5711/5708/5692/5686/595/55294/5702/6233/7525/7311/5694/5693/5691/7314/5595 36 Bluetongue_virus_10 R-HSA-190242 FGFR1 ligand binding and activation 11/1301 16/10654 2.1048078793855884e-7 1.0982344338407062e-6 5.011872751847687e-7 8074/2260/2254/2249/26281/2248/2247/2255/27006/2246/2251 11 Bluetongue_virus_10 R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 11/1301 16/10654 2.1048078793855884e-7 1.0982344338407062e-6 5.011872751847687e-7 5295/6464/5290/5291/6850/4067/2534/6654/2885/9846/5296 11 Bluetongue_virus_10 R-HSA-5654219 Phospholipase C-mediated cascade: FGFR1 11/1301 16/10654 2.1048078793855884e-7 1.0982344338407062e-6 5.011872751847687e-7 8074/2260/2254/2249/26281/2248/2247/2255/27006/2246/2251 11 Bluetongue_virus_10 R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 30/1301 92/10654 2.1987992203295749e-7 1.1426691530548072e-6 5.214653826273057e-7 3725/8945/5601/351/9252/4790/5604/5594/246330/5528/7316/5970/4792/177/5519/5602/6195/7189/5609/6233/6196/7311/5518/6197/5599/7334/7314/5595/5515/5516 30 Bluetongue_virus_10 R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 22/1301 56/10654 2.3578829786216232e-7 1.2190827285231885e-6 5.563372738155933e-7 5718/5689/5684/5682/5690/5717/3315/26986/7316/10213/5711/5708/5692/5686/5702/6233/7311/5694/3312/5693/5691/7314 22 Bluetongue_virus_10 R-HSA-6804757 Regulation of TP53 Degradation 17/1301 36/10654 2.3646813358525525e-7 1.2190827285231885e-6 5.563372738155933e-7 1029/207/7316/890/983/5519/7157/6233/5527/79109/2475/7311/5518/7314/253260/5515/5516 17 Bluetongue_virus_10 R-HSA-69618 Mitotic Spindle Checkpoint 34/1301 112/10654 2.4517073212790867e-7 1.2589322514821978e-6 5.745228935829438e-7 4928/81929/55143/5525/7321/5526/8697/9212/79023/57122/64105/332/8881/5528/5501/5519/5529/51529/64682/29945/10393/11004/5527/7514/9184/5518/5347/29882/6396/25909/140735/996/5515/5516 34 Bluetongue_virus_10 R-HSA-2980766 Nuclear Envelope Breakdown 21/1301 52/10654 2.544392978943453e-7 1.2962379979341842e-6 5.91547642431528e-7 4000/23165/4928/81929/55706/5579/9631/5578/79023/9133/57122/983/9688/7444/8086/2010/4001/23592/5347/6396/7112 21 Bluetongue_virus_10 R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 21/1301 52/10654 2.544392978943453e-7 1.2962379979341842e-6 5.91547642431528e-7 5718/5689/1019/5684/5682/5690/5717/7316/10213/5711/5708/5692/5686/595/5702/6233/7311/5694/5693/5691/7314 21 Bluetongue_virus_10 R-HSA-5218920 VEGFR2 mediated vascular permeability 15/1301 29/10654 2.698741056039624e-7 1.369478794711872e-6 6.249716129775972e-7 1495/1499/207/1500/1003/3320/5063/3728/79109/2475/5058/801/5062/5879/253260 15 Bluetongue_virus_10 R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 30/1301 93/10654 2.87212006173584e-7 1.4461180388662168e-6 6.599464897128022e-7 3725/8945/5601/351/9252/4790/5604/5594/246330/5528/7316/5970/4792/177/5519/5602/6195/7189/5609/6233/6196/7311/5518/6197/5599/7334/7314/5595/5515/5516 30 Bluetongue_virus_10 R-HSA-975155 MyD88 dependent cascade initiated on endosome 30/1301 93/10654 2.87212006173584e-7 1.4461180388662168e-6 6.599464897128022e-7 3725/8945/5601/351/9252/4790/5604/5594/246330/5528/7316/5970/4792/177/5519/5602/6195/7189/5609/6233/6196/7311/5518/6197/5599/7334/7314/5595/5515/5516 30 Bluetongue_virus_10 R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 23/1301 61/10654 3.0346927784891466e-7 1.5220513392887425e-6 6.945992038891927e-7 1072/71/5747/4627/10458/4771/5594/2209/6850/10094/10163/3320/55845/998/695/2885/3326/10097/23191/5058/10109/5879/5595 23 Bluetongue_virus_10 R-HSA-4641258 Degradation of DVL 22/1301 57/10654 3.4012183599370146e-7 1.699295968246524e-6 7.754860800344099e-7 5718/5689/5684/5682/1856/5690/5717/8452/7316/10213/5711/5708/5692/5686/5702/6233/1855/7311/5694/5693/5691/7314 22 Bluetongue_virus_10 R-HSA-5687128 MAPK6/MAPK4 signaling 29/1301 89/10654 3.5538363090542886e-7 1.7687169938139421e-6 8.071668701941119e-7 5718/5689/3725/5684/5682/5690/5717/3315/7316/10213/983/4609/5711/5708/5692/5686/5063/5702/998/6233/7514/7311/5694/5058/5062/5693/5691/7314/5879 29 Bluetongue_virus_10 R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 30/1301 94/10654 3.7327881556512144e-7 1.84387785626465e-6 8.414670766814193e-7 3725/8945/5601/351/9252/4790/5604/7321/5594/5528/7316/5970/4792/177/5519/5602/6195/7189/5609/6233/6196/7311/5518/6197/5599/7334/7314/5595/5515/5516 30 Bluetongue_virus_10 R-HSA-109606 Intrinsic Pathway for Apoptosis 21/1301 53/10654 3.733353928449291e-7 1.84387785626465e-6 8.414670766814193e-7 596/10018/7531/1029/55075/7532/207/10971/5594/7533/2810/7534/6774/54205/598/708/7157/5599/140735/7529/5595 21 Bluetongue_virus_10 R-HSA-69242 S Phase 43/1301 161/10654 3.79611413457405e-7 1.8677458897866237e-6 8.523594274548899e-7 5718/6118/5689/1019/5684/5682/7321/207/8697/5690/5717/286826/8881/7316/10213/5422/890/5426/4609/5711/5427/5708/5692/5985/5686/8243/9126/595/5702/51529/64682/29945/10393/6233/23595/7311/29882/5694/5693/4999/5691/7314/996 43 Bluetongue_virus_10 R-HSA-9612973 Autophagy 35/1301 119/10654 3.84453410984871e-7 1.8749851571133922e-6 8.556631197759806e-7 79643/65018/139341/1459/1915/8878/1080/1460/10533/5116/91782/7316/1457/6714/56993/89853/3320/55054/123/55669/10542/6233/3326/2475/55004/9804/7311/200894/93343/3312/64121/57521/7248/140735/7314 35 Bluetongue_virus_10 R-HSA-166166 MyD88-independent TLR4 cascade 31/1301 99/10654 3.8542971544989356e-7 1.8749851571133922e-6 8.556631197759806e-7 3725/8945/5601/351/9252/4790/5604/7321/5594/5528/7316/5970/4792/177/5519/5602/6195/7189/5609/6233/6196/7311/5518/6197/5599/7334/5781/7314/5595/5515/5516 31 Bluetongue_virus_10 R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 31/1301 99/10654 3.8542971544989356e-7 1.8749851571133922e-6 8.556631197759806e-7 3725/8945/5601/351/9252/4790/5604/7321/5594/5528/7316/5970/4792/177/5519/5602/6195/7189/5609/6233/6196/7311/5518/6197/5599/7334/5781/7314/5595/5515/5516 31 Bluetongue_virus_10 R-HSA-6806003 Regulation of TP53 Expression and Degradation 17/1301 37/10654 3.8793336357143376e-7 1.8800965260727914e-6 8.579957301934727e-7 1029/207/7316/890/983/5519/7157/6233/5527/79109/2475/7311/5518/7314/253260/5515/5516 17 Bluetongue_virus_10 R-HSA-9609736 Assembly and cell surface presentation of NMDA receptors 18/1301 41/10654 4.115334855251623e-7 1.987031083095373e-6 9.067960933999061e-7 818/815/8573/2904/817/10381/2902/55327/2905/2903/816/1741/2906/1742/1739/88/1740/4747 18 Bluetongue_virus_10 R-HSA-5632684 Hedgehog 'on' state 28/1301 85/10654 4.3775912282527486e-7 2.104935688625739e-6 9.606027180664115e-7 5718/5689/5684/5682/1452/5690/5717/409/79577/8452/2737/7316/10213/8650/5711/5708/5692/5686/408/5702/83737/6233/7311/6469/5694/5693/5691/7314 28 Bluetongue_virus_10 R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 10/1301 14/10654 4.4896619015510356e-7 2.104935688625739e-6 9.606027180664115e-7 5525/5526/1452/5528/5519/5529/5527/5518/5515/5516 10 Bluetongue_virus_10 R-HSA-4839744 truncated APC mutants destabilize the destruction complex 10/1301 14/10654 4.4896619015510356e-7 2.104935688625739e-6 9.606027180664115e-7 5525/5526/1452/5528/5519/5529/5527/5518/5515/5516 10 Bluetongue_virus_10 R-HSA-4839748 AMER1 mutants destabilize the destruction complex 10/1301 14/10654 4.4896619015510356e-7 2.104935688625739e-6 9.606027180664115e-7 5525/5526/1452/5528/5519/5529/5527/5518/5515/5516 10 Bluetongue_virus_10 R-HSA-5467337 APC truncation mutants have impaired AXIN binding 10/1301 14/10654 4.4896619015510356e-7 2.104935688625739e-6 9.606027180664115e-7 5525/5526/1452/5528/5519/5529/5527/5518/5515/5516 10 Bluetongue_virus_10 R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 10/1301 14/10654 4.4896619015510356e-7 2.104935688625739e-6 9.606027180664115e-7 5525/5526/1452/5528/5519/5529/5527/5518/5515/5516 10 Bluetongue_virus_10 R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 10/1301 14/10654 4.4896619015510356e-7 2.104935688625739e-6 9.606027180664115e-7 5525/5526/1452/5528/5519/5529/5527/5518/5515/5516 10 Bluetongue_virus_10 R-HSA-8983432 Interleukin-15 signaling 10/1301 14/10654 4.4896619015510356e-7 2.104935688625739e-6 9.606027180664115e-7 6464/3561/3560/6774/3718/6654/2885/3716/9846/6655 10 Bluetongue_virus_10 R-HSA-1169091 Activation of NF-kappaB in B cells 24/1301 67/10654 5.109588052425201e-7 2.3869339132989925e-6 1.0892946598558e-6 5718/5689/8945/5684/4790/5579/5682/5690/5717/7316/10213/5970/4792/5711/5708/5692/5686/5702/6233/7311/5694/5693/5691/7314 24 Bluetongue_virus_10 R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 21/1301 54/10654 5.412332657009012e-7 2.51926563243513e-6 1.1496852027951745e-6 10450/9318/6917/27339/5430/5436/5431/7316/64708/5437/10920/2033/2068/10987/2071/6233/7311/57461/5432/7314/51138 21 Bluetongue_virus_10 R-HSA-448424 Interleukin-17 signaling 25/1301 72/10654 5.873339702115326e-7 2.7240507435617315e-6 1.2431403783764188e-6 3725/8945/5601/9252/4790/5604/5594/5528/7316/5519/5602/6195/7189/5609/6233/6196/7311/5518/6197/5599/7334/7314/5595/5515/5516 25 Bluetongue_virus_10 R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 20/1301 50/10654 5.89888476321243e-7 2.7261274584274585e-6 1.2440881023166066e-6 5718/5689/5684/5682/5690/5717/7316/10213/5711/5708/5692/5686/5702/6233/7311/5694/5062/5693/5691/7314 20 Bluetongue_virus_10 R-HSA-69306 DNA Replication 36/1301 127/10654 7.114571188227003e-7 3.2762473727991963e-6 1.495139328187057e-6 5718/6118/5689/5684/5682/7321/8697/5690/5717/8881/7316/10213/5422/890/5426/5711/5427/5708/5692/5985/5686/5702/51529/64682/29945/10393/6233/23595/7311/29882/5694/5693/4999/5691/7314/996 36 Bluetongue_virus_10 R-HSA-6794362 Protein-protein interactions at synapses 28/1301 87/10654 7.497893446000682e-7 3.4405227372783267e-6 1.5701075861166042e-6 8573/8496/2035/2904/10211/2319/2036/26050/2902/23136/22839/57669/9369/55327/2905/8500/2903/2037/84631/9066/1741/2906/1742/1739/1740/8495/4916/3556 28 Bluetongue_virus_10 R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 21/1301 55/10654 7.756939800487129e-7 3.54681275683051e-6 1.618613809958445e-6 5718/5689/8945/26271/5684/5682/5690/5717/7316/10213/5711/5708/5692/5686/5702/6233/7311/5694/5693/5691/7314 21 Bluetongue_virus_10 R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 30/1301 97/10654 7.960993954641385e-7 3.627297949755617e-6 1.655343813400229e-6 3725/8945/5601/351/9252/4790/5604/5594/246330/5528/7316/5970/4792/177/5519/5602/6195/7189/5609/6233/6196/7311/5518/6197/5599/7334/7314/5595/5515/5516 30 Bluetongue_virus_10 R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 15/1301 31/10654 8.235893923398277e-7 3.7263100478592204e-6 1.7005287048312233e-6 3725/5601/9252/5594/5528/5519/5602/6195/6196/5518/6197/5599/5595/5515/5516 15 Bluetongue_virus_10 R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 15/1301 31/10654 8.235893923398277e-7 3.7263100478592204e-6 1.7005287048312233e-6 1499/5525/1856/5526/10023/1452/5528/5519/5529/5527/1855/4040/5518/5515/5516 15 Bluetongue_virus_10 R-HSA-1839130 Signaling by activated point mutants of FGFR3 9/1301 12/10654 9.166516786079703e-7 4.090163007305909e-6 1.8665756504503494e-6 8823/8074/8817/2254/2249/26281/2261/2247/2246 9 Bluetongue_virus_10 R-HSA-2033514 FGFR3 mutant receptor activation 9/1301 12/10654 9.166516786079703e-7 4.090163007305909e-6 1.8665756504503494e-6 8823/8074/8817/2254/2249/26281/2261/2247/2246 9 Bluetongue_virus_10 R-HSA-9020558 Interleukin-2 signaling 9/1301 12/10654 9.166516786079703e-7 4.090163007305909e-6 1.8665756504503494e-6 6464/3561/3560/6850/3718/3558/3716/3932/3559 9 Bluetongue_virus_10 R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 9/1301 12/10654 9.166516786079703e-7 4.090163007305909e-6 1.8665756504503494e-6 5295/5290/5291/4067/3717/5294/8660/5293/2549 9 Bluetongue_virus_10 R-HSA-114604 GPVI-mediated activation cascade 16/1301 35/10654 9.317806333661727e-7 4.143381922940988e-6 1.890862489847795e-6 5295/5590/5290/5291/6850/8503/146850/4067/5294/2534/998/3932/387/5296/5781/5879 16 Bluetongue_virus_10 R-HSA-8948751 Regulation of PTEN stability and activity 24/1301 69/10654 9.494829957545365e-7 4.192067240562283e-6 1.9130803888029296e-6 5718/5689/5684/5682/1459/207/5690/5717/1460/7316/10213/1457/5711/5708/5692/5686/5728/5702/6233/7311/5694/5693/5691/7314 24 Bluetongue_virus_10 R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 22/1301 60/10654 9.589272822306305e-7 4.192067240562283e-6 1.9130803888029296e-6 5718/5689/1019/5684/5682/5690/5717/7316/10213/890/5711/5708/5692/5686/595/5702/6233/7311/5694/5693/5691/7314 22 Bluetongue_virus_10 R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 22/1301 60/10654 9.589272822306305e-7 4.192067240562283e-6 1.9130803888029296e-6 5718/5689/8945/5684/5682/5690/5717/7316/10213/5970/5711/5708/5692/5686/5702/9040/6233/7311/5694/5693/5691/7314 22 Bluetongue_virus_10 R-HSA-5610780 Degradation of GLI1 by the proteasome 22/1301 60/10654 9.589272822306305e-7 4.192067240562283e-6 1.9130803888029296e-6 5718/5689/8945/5684/5682/5690/5717/7316/10213/8650/5711/5708/5692/5686/5702/83737/6233/7311/5694/5693/5691/7314 22 Bluetongue_virus_10 R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 22/1301 60/10654 9.589272822306305e-7 4.192067240562283e-6 1.9130803888029296e-6 5718/5689/8945/5684/5682/1452/5690/5717/2737/7316/10213/5711/5708/5692/5686/5702/6233/7311/5694/5693/5691/7314 22 Bluetongue_virus_10 R-HSA-382556 ABC-family proteins mediated transport 31/1301 103/10654 1.015406364487865e-6 4.409180656534554e-6 2.0121616760073907e-6 5718/5689/5684/1965/5682/5243/5690/91445/5717/1080/1244/7316/10213/340273/5711/5825/8894/5708/5692/5686/5702/6233/7311/11160/5694/4363/10057/5693/5691/7314/1968 31 Bluetongue_virus_10 R-HSA-9020702 Interleukin-1 signaling 31/1301 103/10654 1.015406364487865e-6 4.409180656534554e-6 2.0121616760073907e-6 5718/5689/8945/5684/351/4790/5682/5604/5690/8878/5717/246330/7316/10213/5970/4792/177/5711/5708/5692/5686/5702/7189/6233/7311/7334/5694/5693/5691/7314/3556 31 Bluetongue_virus_10 R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 36/1301 129/10654 1.0743483652823364e-6 4.649521018981082e-6 2.1218427492462267e-6 3725/8945/5601/351/9252/4790/5604/7321/5594/1785/246330/5528/7316/5970/4792/59307/177/26052/5519/5602/6195/695/7189/5609/6233/6196/7311/5518/6197/5599/7334/5781/7314/5595/5515/5516 36 Bluetongue_virus_10 R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 21/1301 56/10654 1.0996373893606637e-6 4.743102606108996e-6 2.164549387478359e-6 5718/5689/5684/5682/5690/5717/84447/7316/10213/5711/5708/5692/5686/5702/6233/7311/6469/5694/5693/5691/7314 21 Bluetongue_virus_10 R-HSA-180534 Vpu mediated degradation of CD4 20/1301 52/10654 1.2384645895930978e-6 5.306533705077711e-6 2.4216752692984593e-6 5718/5689/8945/5684/5682/5690/5717/7316/10213/5711/5708/5692/5686/5702/6233/7311/5694/5693/5691/7314 20 Bluetongue_virus_10 R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 20/1301 52/10654 1.2384645895930978e-6 5.306533705077711e-6 2.4216752692984593e-6 5718/5689/5684/5682/5690/5717/7316/10213/5711/5708/5692/5686/5702/7157/6233/7311/5694/5693/5691/7314 20 Bluetongue_virus_10 R-HSA-8856828 Clathrin-mediated endocytosis 39/1301 146/10654 1.3047468817350623e-6 5.572087343119375e-6 2.542862604319507e-6 9318/1173/1839/85439/685/71/8674/1856/2069/1785/409/1080/382/7316/1950/64708/10094/22905/26052/7037/9341/10920/3482/408/10987/115548/6233/2885/6844/10097/7311/6845/1956/3312/8673/10109/7314/51138/11252 39 Bluetongue_virus_10 R-HSA-5678895 Defective CFTR causes cystic fibrosis 22/1301 61/10654 1.3286728231639143e-6 5.655600767020083e-6 2.5809745630019254e-6 5718/5689/5684/5682/5690/91445/5717/1080/7316/10213/5711/5708/5692/5686/5702/6233/7311/11160/5694/5693/5691/7314 22 Bluetongue_virus_10 R-HSA-397795 G-protein beta:gamma signalling 15/1301 32/10654 1.3759242064852668e-6 5.837527617022738e-6 2.6639982047911466e-6 5331/59345/207/9459/146850/23236/5294/2783/2784/2782/998/695/387/5058/2787 15 Bluetongue_virus_10 R-HSA-69541 Stabilization of p53 21/1301 57/10654 1.5426881288247085e-6 6.52365502842867e-6 2.977117441591543e-6 5718/5689/5684/5682/1029/5690/5717/7316/10213/5711/5708/5692/5686/5702/7157/6233/7311/5694/5693/5691/7314 21 Bluetongue_virus_10 R-HSA-110056 MAPK3 (ERK1) activation 8/1301 10/10654 1.7376036957641117e-6 7.300192150385586e-6 3.3314958076680336e-6 5604/983/3717/3716/5781/3569/3572/5595 8 Bluetongue_virus_10 R-HSA-74749 Signal attenuation 8/1301 10/10654 1.7376036957641117e-6 7.300192150385586e-6 3.3314958076680336e-6 3643/6464/3667/5594/6654/2885/8660/5595 8 Bluetongue_virus_10 R-HSA-169911 Regulation of Apoptosis 20/1301 53/10654 1.762785314895007e-6 7.382020056550612e-6 3.3688385680671057e-6 5718/5689/5684/5682/5690/5717/7316/10213/5711/5708/5692/5686/5702/6233/7311/5694/5062/5693/5691/7314 20 Bluetongue_virus_10 R-HSA-5619115 Disorders of transmembrane transporters 44/1301 176/10654 1.9940828365229167e-6 8.30556701329798e-6 3.7903059419671094e-6 5718/23165/5689/4928/6507/81929/5684/55706/5682/9631/5690/91445/5717/1080/7355/79023/9843/57122/1244/7316/10213/3098/9688/5711/682/5708/5692/5686/5702/8086/4891/1836/6520/6233/7311/6575/11160/6396/5694/9197/5693/5691/6566/7314 44 Bluetongue_virus_10 R-HSA-5205647 Mitophagy 14/1301 29/10654 1.9961602327169026e-6 8.30556701329798e-6 3.7903059419671094e-6 65018/139341/1459/8878/1460/7316/1457/6714/56993/55669/6233/9804/7311/7314 14 Bluetongue_virus_10 R-HSA-9613829 Chaperone Mediated Autophagy 12/1301 22/10654 2.085555208396374e-6 8.649706537387525e-6 3.947356517916215e-6 1915/1080/5116/7316/3320/123/6233/3326/7311/200894/3312/7314 12 Bluetongue_virus_10 R-HSA-112316 Neuronal System 83/1301 413/10654 2.2000527169847308e-6 9.095425609515149e-6 4.150763659755958e-6 5923/818/1173/6507/815/3838/8573/4893/9254/8496/2035/5579/5331/2904/59345/90134/2770/817/10211/5578/5594/2319/2036/112/26050/114/10381/5573/2902/23136/22839/57669/80852/9369/6714/54407/24145/55327/2905/8500/81539/27330/2903/23236/2037/3084/84631/9066/6195/2783/2784/9495/2782/816/2066/4905/1741/2906/2771/10550/1742/1739/22999/6844/88/6196/10052/1740/8495/6197/3845/115/3265/3312/801/5924/4747/2773/4916/5879/5595/2787/3556 83 Bluetongue_virus_10 R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 24/1301 72/10654 2.2740184073421557e-6 9.371273309238055e-6 4.276648764729968e-6 8773/55763/71/7531/4627/7532/207/10971/57186/7533/2810/10381/7534/5872/60412/5898/11336/51552/6844/4012/801/7529/6814/5879 24 Bluetongue_virus_10 R-HSA-168898 Toll-like Receptor Cascades 40/1301 155/10654 2.4728100588895097e-6 1.012889865905209e-5 4.622396605977567e-6 3725/8945/5601/351/9252/4790/5604/7321/5594/1785/246330/5528/7316/5970/4792/59307/6279/177/26052/5519/2244/5602/6195/695/7189/5609/6233/2266/6196/7311/5518/2243/6197/5599/7334/5781/7314/5595/5515/5516 40 Bluetongue_virus_10 R-HSA-112043 PLC beta mediated events 20/1301 54/10654 2.4813453438326987e-6 1.012889865905209e-5 4.622396605977567e-6 818/815/3838/5331/2770/817/5578/5594/112/114/2779/5573/10768/23236/816/2771/5580/115/801/2773 20 Bluetongue_virus_10 R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 20/1301 54/10654 2.4813453438326987e-6 1.012889865905209e-5 4.622396605977567e-6 5718/5689/5684/5682/5690/5717/7316/10213/6790/5711/5708/5692/5686/5702/6233/7311/5694/5693/5691/7314 20 Bluetongue_virus_10 R-HSA-176412 Phosphorylation of the APC/C 11/1301 19/10654 2.562744968914666e-6 1.0428276697407478e-5 4.759019952204991e-6 7321/8697/8881/983/51529/64682/29945/10393/5347/29882/996 11 Bluetongue_virus_10 R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 9/1301 13/10654 2.654845234322136e-6 1.0635819607470105e-5 4.853733669397811e-6 2065/207/2064/7316/3084/9542/6233/7311/7314 9 Bluetongue_virus_10 R-HSA-190239 FGFR3 ligand binding and activation 9/1301 13/10654 2.654845234322136e-6 1.0635819607470105e-5 4.853733669397811e-6 8823/8074/8817/2254/2249/26281/2261/2247/2246 9 Bluetongue_virus_10 R-HSA-190372 FGFR3c ligand binding and activation 9/1301 13/10654 2.654845234322136e-6 1.0635819607470105e-5 4.853733669397811e-6 8823/8074/8817/2254/2249/26281/2261/2247/2246 9 Bluetongue_virus_10 R-HSA-209560 NF-kB is activated and signals survival 9/1301 13/10654 2.654845234322136e-6 1.0635819607470105e-5 4.853733669397811e-6 4790/8878/7316/5970/4792/7189/6233/7311/7314 9 Bluetongue_virus_10 R-HSA-5654227 Phospholipase C-mediated cascade; FGFR3 9/1301 13/10654 2.654845234322136e-6 1.0635819607470105e-5 4.853733669397811e-6 8823/8074/8817/2254/2249/26281/2261/2247/2246 9 Bluetongue_virus_10 R-HSA-193639 p75NTR signals via NF-kB 10/1301 16/10654 2.8464388605607895e-6 1.1368184831992783e-5 5.187953868663428e-6 4790/5584/8878/7316/5970/4792/7189/6233/7311/7314 10 Bluetongue_virus_10 R-HSA-3700989 Transcriptional Regulation by TP53 75/1301 365/10654 2.9191980291361037e-6 1.1622899229852672e-5 5.3041946375558034e-6 6118/3725/6917/5305/7531/1029/1459/7486/5430/7532/207/10971/5436/1345/55240/9212/4869/7533/2810/1460/4292/545/7534/332/580/5431/7316/6872/890/1457/983/54205/6790/5519/4683/5437/83860/23019/2821/28984/6794/5985/54815/2033/5728/2068/2071/7157/5371/10498/10542/6233/5527/79109/1349/2475/55004/7311/5518/10419/5300/1340/11198/5810/64121/10397/5432/57521/7248/26155/7529/7314/253260/5515/5516 75 Bluetongue_virus_10 R-HSA-5387390 Hh mutants abrogate ligand secretion 21/1301 59/10654 2.948071633340494e-6 1.1630502114459144e-5 5.307664269268348e-6 5718/5689/5684/5682/5690/5717/84447/7316/10213/5711/5708/5692/5686/5702/6233/7311/6469/5694/5693/5691/7314 21 Bluetongue_virus_10 R-HSA-5676590 NIK-->noncanonical NF-kB signaling 21/1301 59/10654 2.948071633340494e-6 1.1630502114459144e-5 5.307664269268348e-6 5718/5689/8945/5684/5682/5690/5717/7316/10213/5711/5708/5692/5686/5702/9040/6233/7311/5694/5693/5691/7314 21 Bluetongue_virus_10 R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 21/1301 59/10654 2.948071633340494e-6 1.1630502114459144e-5 5.307664269268348e-6 5718/5689/5684/5682/5690/5717/7316/10213/5711/5708/5692/5686/5702/6233/23595/7311/5694/5693/4999/5691/7314 21 Bluetongue_virus_10 R-HSA-5610787 Hedgehog 'off' state 32/1301 113/10654 2.9829344275023777e-6 1.1732270970176524e-5 5.354107227095934e-6 5718/5689/8945/5684/5682/1452/5690/79809/5717/112/114/10381/7289/5573/2737/7316/10213/2778/8650/5711/5708/5692/5686/5702/83737/6233/7311/115/5694/5693/5691/7314 32 Bluetongue_virus_10 R-HSA-69275 G2/M Transition 47/1301 196/10654 3.1573434179404044e-6 1.2380613281257223e-5 5.649982958419673e-6 5718/5689/8945/5684/5682/7531/10142/7532/63943/5690/5717/121441/9133/10381/5116/286826/7316/10213/890/983/6790/9702/5519/5711/5708/3320/5692/5686/2033/10426/5702/10540/7157/6233/3326/7514/7311/5518/5347/5694/27229/5693/10806/5691/7314/5515/5516 47 Bluetongue_virus_10 R-HSA-3928663 EPHA-mediated growth cone collapse 14/1301 30/10654 3.32369457371533e-6 1.2993537094826699e-5 5.929695200681509e-6 2042/4627/2041/6714/4637/4067/2043/2534/9475/4628/7525/6093/387/1969 14 Bluetongue_virus_10 R-HSA-4608870 Asymmetric localization of PCP proteins 22/1301 64/10654 3.353016602893784e-6 1.3068685193206496e-5 5.963989582192178e-6 5718/5689/5684/5682/1856/5690/5717/7316/10213/5711/5708/5692/5686/5702/23513/57216/6233/7311/5694/5693/5691/7314 22 Bluetongue_virus_10 R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 17/1301 42/10654 3.408793738442424e-6 1.32461834761096e-5 6.044992215161056e-6 10694/59345/1459/2770/1460/2779/7203/10576/1457/2783/2784/2782/2771/10574/22948/2773/2787 17 Bluetongue_virus_10 R-HSA-112040 G-protein mediated events 20/1301 55/10654 3.456003265994972e-6 1.3389425826938603e-5 6.110361904264669e-6 818/815/3838/5331/2770/817/5578/5594/112/114/2779/5573/10768/23236/816/2771/5580/115/801/2773 20 Bluetongue_virus_10 R-HSA-5610783 Degradation of GLI2 by the proteasome 21/1301 60/10654 4.019149360861208e-6 1.5524714247625084e-5 7.084816312468619e-6 5718/5689/8945/5684/5682/1452/5690/5717/7316/10213/5711/5708/5692/5686/5702/6233/7311/5694/5693/5691/7314 21 Bluetongue_virus_10 R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 25/1301 79/10654 4.1033804120797304e-006 1.580289956318801e-5 7.2117682054408805e-6 10450/9318/6118/6917/27339/5430/5436/5431/7316/64708/5426/5437/5427/5985/10920/2033/2068/10987/2071/6233/7311/57461/5432/7314/51138 25 Bluetongue_virus_10 R-HSA-453274 Mitotic G2-G2/M phases 47/1301 198/10654 4.251558434968092e-6 1.6324975118245432e-5 7.450021183873496e-6 5718/5689/8945/5684/5682/7531/10142/7532/63943/5690/5717/121441/9133/10381/5116/286826/7316/10213/890/983/6790/9702/5519/5711/5708/3320/5692/5686/2033/10426/5702/10540/7157/6233/3326/7514/7311/5518/5347/5694/27229/5693/10806/5691/7314/5515/5516 47 Bluetongue_virus_10 R-HSA-373755 Semaphorin interactions 22/1301 65/10654 4.490692761705071e-6 1.7192178797770298e-5 7.845775893231219e-6 10154/1072/5361/4627/2909/7094/2064/3688/4233/4637/3320/5063/2534/9475/4628/3326/6093/10507/387/5058/5062/5879 22 Bluetongue_virus_10 R-HSA-202733 Cell surface interactions at the vascular wall 36/1301 137/10654 4.983409216502631e-6 1.9022216891310926e-5 8.680927093488514e-6 5295/4893/6464/5290/960/5291/2995/1525/7010/83700/3678/50848/3688/8140/6714/4973/4067/140885/682/2335/2534/3690/6520/6654/2885/7525/23657/3932/5296/3845/3265/5781/6566/284/9046/3655 36 Bluetongue_virus_10 R-HSA-1234174 Cellular response to hypoxia 24/1301 75/10654 5.122901057381577e-6 1.9497158730152235e-5 8.897670257557475e-6 5718/5689/5684/5682/7321/7422/5690/5717/7316/10213/5711/5708/5692/5686/2033/5702/6233/7311/54583/5694/405/5693/5691/7314 24 Bluetongue_virus_10 R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 25/1301 80/10654 5.285703855575975e-6 2.0057773575118216e-5 9.15351092137096e-6 23165/4928/3838/81929/55706/9631/79023/57122/1982/7706/7316/9688/6059/8086/9246/6233/3716/7311/5300/9775/6396/7334/4938/7314/5595 25 Bluetongue_virus_10 R-HSA-8939211 ESR-mediated signaling 51/1301 223/10654 5.310324253527497e-6 2.0092279485568952e-5 9.169257944687368e-6 5295/3725/3838/596/5590/1839/4893/6464/685/5290/5747/59345/5430/2770/207/5436/5594/2069/3315/5431/1950/865/6714/4609/8503/5437/3320/2033/8243/9126/595/2783/2784/2782/2066/2771/10498/3326/7514/1956/5536/5296/3845/3265/801/8877/5432/3480/2773/5595/2787 51 Bluetongue_virus_10 R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 19/1301 52/10654 5.5745397297263945e-6 2.090856350801726e-5 9.54177509802138e-6 5718/5689/5684/5682/5690/5717/7316/10213/5711/5708/5692/5686/5702/6233/7311/5694/5693/5691/7314 19 Bluetongue_virus_10 R-HSA-69610 p53-Independent DNA Damage Response 19/1301 52/10654 5.5745397297263945e-6 2.090856350801726e-5 9.54177509802138e-6 5718/5689/5684/5682/5690/5717/7316/10213/5711/5708/5692/5686/5702/6233/7311/5694/5693/5691/7314 19 Bluetongue_virus_10 R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 19/1301 52/10654 5.5745397297263945e-6 2.090856350801726e-5 9.54177509802138e-6 5718/5689/5684/5682/5690/5717/7316/10213/5711/5708/5692/5686/5702/6233/7311/5694/5693/5691/7314 19 Bluetongue_virus_10 R-HSA-1839122 Signaling by activated point mutants of FGFR1 8/1301 11/10654 5.685369342931302e-6 2.126262407443094e-5 9.703353213825557e-6 8074/2260/2254/2249/26281/2247/2246/2251 8 Bluetongue_virus_10 R-HSA-5633007 Regulation of TP53 Activity 40/1301 160/10654 5.762246941185727e-6 2.1488033261943318e-5 9.806220336736517e-6 6118/5305/1029/1459/7486/207/9212/1460/545/580/7316/6872/890/1457/983/6790/5519/4683/83860/6794/5985/54815/2033/7157/5371/6233/5527/79109/2475/7311/5518/10419/5300/11198/5810/26155/7314/253260/5515/5516 40 Bluetongue_virus_10 R-HSA-5358351 Signaling by Hedgehog 38/1301 149/10654 5.930648105670808e-6 2.2052467381431105e-5 1.0063803954268975e-5 5718/5689/8945/5684/5682/1452/5690/79809/5717/409/79577/112/114/10381/7289/5573/8452/2737/84447/7316/10213/2778/8650/5711/5708/5692/5686/408/5702/83737/6233/7311/6469/115/5694/5693/5691/7314 38 Bluetongue_virus_10 R-HSA-69563 p53-Dependent G1 DNA Damage Response 22/1301 66/10654 5.9683512398528e-6 2.2065847155341492e-5 1.006990991145089e-5 5718/5689/5684/5682/1029/5690/5717/7316/10213/890/5711/5708/5692/5686/5702/7157/6233/7311/5694/5693/5691/7314 22 Bluetongue_virus_10 R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 22/1301 66/10654 5.9683512398528e-6 2.2065847155341492e-5 1.006990991145089e-5 5718/5689/5684/5682/1029/5690/5717/7316/10213/890/5711/5708/5692/5686/5702/7157/6233/7311/5694/5693/5691/7314 22 Bluetongue_virus_10 R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 30/1301 106/10654 6.112626069795329e-6 2.253486647953036e-5 1.0283950292863039e-5 9318/1173/1839/85439/685/8674/1856/2069/409/1080/7316/1950/64708/22905/7037/9341/10920/3482/408/10987/115548/6233/2885/6844/7311/6845/1956/8673/7314/51138 30 Bluetongue_virus_10 R-HSA-432142 Platelet sensitization by LDL 10/1301 17/10654 6.15510323152203e-6 2.2626998811333825e-5 1.0325995552882356e-5 5525/5526/5528/5519/5529/5527/5518/5781/5515/5516 10 Bluetongue_virus_10 R-HSA-169893 Prolonged ERK activation events 9/1301 14/10654 6.625427513822806e-6 2.421837062962348e-5 1.1052229661773996e-5 5604/5594/673/57498/5605/10818/5906/7529/5595 9 Bluetongue_virus_10 R-HSA-9027284 Erythropoietin activates RAS 9/1301 14/10654 6.625427513822806e-6 2.421837062962348e-5 1.1052229661773996e-5 4893/6464/4067/3717/6654/2885/8660/3845/3265 9 Bluetongue_virus_10 R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 12/1301 24/10654 6.893353381211977e-6 2.512675852193887e-5 1.1466779086315552e-5 596/1839/685/5747/207/5594/2069/1950/595/7514/1956/5595 12 Bluetongue_virus_10 R-HSA-6790901 rRNA modification in the nucleus and cytosol 21/1301 62/10654 7.27923749483296e-6 2.645880145593778e-5 1.2074666571854792e-5 9136/2091/6203/55651/55813/6194/25879/10528/4839/88745/51602/134430/55272/92856/9790/51077/10199/55505/51202/6187/6208 21 Bluetongue_virus_10 R-HSA-1169408 ISG15 antiviral mechanism 23/1301 72/10654 8.28900305331334e-6 3.0044733756267398e-5 1.3711132870142367e-5 23165/4928/3838/81929/55706/9631/79023/57122/1982/7706/7316/9688/8086/9246/6233/3716/7311/5300/9775/6396/7334/7314/5595 23 Bluetongue_virus_10 R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 15/1301 36/10654 8.40846775609369e-6 3.039261809046155e-5 1.3869892417431816e-5 71/5747/10458/5594/10094/10163/55845/998/695/2885/10097/23191/10109/5879/5595 15 Bluetongue_virus_10 R-HSA-1500931 Cell-Cell communication 34/1301 129/10654 8.440895198417445e-6 3.040259704818534e-5 1.3874446387400942e-5 5295/8573/6711/1365/9076/5290/71/5291/1495/1499/5584/5747/9459/50848/3688/1500/23705/6714/1003/140885/999/2534/10979/3728/64398/2885/6709/88/56288/8826/5296/55742/5781/3655 34 Bluetongue_virus_10 R-HSA-446652 Interleukin-1 family signaling 36/1301 140/10654 8.481713705096528e-6 3.040259704818534e-5 1.3874446387400942e-5 5718/5689/8945/5684/351/4790/5682/5604/5690/8878/5717/246330/7316/10213/6774/5970/4792/59307/177/5711/5708/5692/5686/5702/7189/6233/7311/5599/5784/7334/5694/5781/5693/5691/7314/3556 36 Bluetongue_virus_10 R-HSA-6807070 PTEN Regulation 36/1301 140/10654 8.481713705096528e-6 3.040259704818534e-5 1.3874446387400942e-5 5718/5689/3725/5684/5682/1459/2146/207/5690/5594/5717/1460/7316/10213/1457/5711/5708/5692/54815/5686/5728/5702/7157/5371/10542/6233/2475/55004/7311/5694/64121/57521/5693/5691/7314/5595 36 Bluetongue_virus_10 R-HSA-69615 G1/S DNA Damage Checkpoints 22/1301 68/10654 1.0313817409402275e-5 3.686762355736614e-5 1.6824808277623367e-5 5718/5689/5684/5682/1029/5690/5717/7316/10213/890/5711/5708/5692/5686/5702/7157/6233/7311/5694/5693/5691/7314 22 Bluetongue_virus_10 R-HSA-983169 Class I MHC mediated antigen processing & presentation 74/1301 371/10654 1.0360011425866234e-5 3.693072943545704e-5 1.685360710428e-5 5718/8773/5689/8945/5684/64410/10952/5682/26046/3107/7321/9021/8697/5690/7174/5717/821/811/10533/2209/9554/8881/8452/23376/7316/10213/29927/7317/54926/4008/5711/23327/10134/9341/51465/5708/5692/5686/89910/55521/25898/55294/7328/5702/83737/51529/9040/695/10075/64682/29945/9246/10393/80176/9902/6233/56658/4012/7311/9320/29882/6396/7334/92591/5930/5694/84961/8673/29116/3105/5693/5691/7314/996 74 Bluetongue_virus_10 R-HSA-180585 Vif-mediated degradation of APOBEC3G 19/1301 54/10654 1.0540139396032603e-5 3.746961642435766e-5 1.7099532102875335e-5 5718/5689/5684/5682/5690/5717/7316/10213/5711/5708/5692/5686/5702/6233/7311/5694/5693/5691/7314 19 Bluetongue_virus_10 R-HSA-422356 Regulation of insulin secretion 24/1301 78/10654 1.0919879453776446e-5 3.865692943352385e-5 1.7641371034090034e-5 9254/5331/59345/2770/5578/112/114/4082/5573/2778/10768/23236/2783/2784/9495/2782/2776/2771/6844/8826/5906/2182/2181/2787 24 Bluetongue_virus_10 R-HSA-69202 Cyclin E associated events during G1/S transition 25/1301 83/10654 1.093387648583441e-5 3.865692943352385e-5 1.7641371034090034e-5 5718/5689/1019/5684/5682/207/5690/5717/286826/7316/10213/890/4609/5711/5708/5692/5686/595/5702/6233/7311/5694/5693/5691/7314 25 Bluetongue_virus_10 R-HSA-72202 Transport of Mature Transcript to Cytoplasm 25/1301 84/10654 1.3787702419045521e-5 4.861386084535396e-5 2.2185289135478382e-5 10921/23165/4928/81929/55706/9631/29894/79023/57122/81608/9785/11338/4116/9688/9984/10250/10569/10482/8086/9939/9775/6396/79228/2733/6426 25 Bluetongue_virus_10 R-HSA-4641257 Degradation of AXIN 19/1301 55/10654 1.4278989020219076e-5 5.0209271174357295e-5 2.291336624812043e-5 5718/5689/5684/5682/5690/5717/7316/10213/5711/5708/5692/5686/5702/6233/7311/5694/5693/5691/7314 19 Bluetongue_virus_10 R-HSA-111447 Activation of BAD and translocation to mitochondria 9/1301 15/10654 1.476512118679916e-5 5.177795885018459e-5 2.3629248283538237e-5 596/7531/7532/207/10971/7533/2810/7534/7529 9 Bluetongue_virus_10 R-HSA-170968 Frs2-mediated activation 8/1301 12/10654 1.5222804671577948e-5 5.295244420704803e-5 2.416523322228418e-5 5604/5594/673/5605/10818/5906/7529/5595 8 Bluetongue_virus_10 R-HSA-190373 FGFR1c ligand binding and activation 8/1301 12/10654 1.5222804671577948e-5 5.295244420704803e-5 2.416523322228418e-5 8074/2260/2254/2249/26281/2247/2246/2251 8 Bluetongue_virus_10 R-HSA-389359 CD28 dependent Vav1 pathway 8/1301 12/10654 1.5222804671577948e-5 5.295244420704803e-5 2.416523322228418e-5 5063/2534/998/2885/3932/5058/5062/5879 8 Bluetongue_virus_10 R-HSA-1632852 Macroautophagy 27/1301 95/10654 1.6172687304129534e-5 5.610578383791855e-5 2.560428270810405e-5 79643/65018/139341/1459/8878/1460/10533/91782/7316/1457/6714/56993/55054/123/55669/10542/6233/2475/55004/9804/7311/3312/64121/57521/7248/140735/7314 27 Bluetongue_virus_10 R-HSA-5358346 Hedgehog ligand biogenesis 21/1301 65/10654 1.671485340631896e-5 5.7831605101007314e-5 2.639187379945099e-5 5718/5689/5684/5682/5690/5717/84447/7316/10213/5711/5708/5692/5686/5702/6233/7311/6469/5694/5693/5691/7314 21 Bluetongue_virus_10 R-HSA-198753 ERK/MAPK targets 11/1301 22/10654 1.68475449096903e-5 5.8135261635037994e-5 2.6530449668312306e-5 9252/5594/5528/5519/6195/6196/5518/6197/5595/5515/5516 11 Bluetongue_virus_10 R-HSA-3928665 EPH-ephrin mediated repulsion of cells 18/1301 51/10654 1.708350588199573e-5 5.879270375346403e-5 2.6830478162932828e-5 1173/71/2042/1947/7074/1949/2041/102/6714/4067/2043/2534/1948/2048/7525/5663/1969/5879 18 Bluetongue_virus_10 R-HSA-69002 DNA Replication Pre-Initiation 25/1301 85/10654 1.7300743243318857e-5 5.92252956530545e-5 2.7027894624065384e-5 5718/6118/5689/5684/5682/5690/5717/7316/10213/5422/5426/5711/5427/5708/5692/5686/5702/6233/23595/7311/5694/5693/4999/5691/7314 25 Bluetongue_virus_10 R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 25/1301 85/10654 1.7300743243318857e-5 5.92252956530545e-5 2.7027894624065384e-5 5718/5689/1019/5684/5682/207/5690/5717/286826/7316/10213/890/4609/5711/5708/5692/5686/595/5702/6233/7311/5694/5693/5691/7314 25 Bluetongue_virus_10 R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 23/1301 75/10654 1.7613859424222376e-5 6.01380846832289e-5 2.7444452539893776e-5 10921/23165/4928/81929/55706/9631/79023/57122/9785/11338/4116/9688/9984/10250/10569/10482/8086/9939/9775/6396/79228/2733/6426 23 Bluetongue_virus_10 R-HSA-201681 TCF dependent signaling in response to WNT 51/1301 233/10654 1.9401519081492863e-5 6.606727813539939e-5 3.015028311556093e-5 5718/5689/8945/5684/7015/5682/1499/5525/864/1459/1856/5526/10023/207/1452/5690/5717/5929/79577/1460/7534/8452/5528/7316/10213/1457/4609/5519/5711/5708/5692/5686/2033/5529/5702/6233/5527/1855/7514/4040/7311/79412/5518/8607/6659/5694/5693/5691/7314/5515/5516 51 Bluetongue_virus_10 R-HSA-114452 Activation of BH3-only proteins 13/1301 30/10654 2.0306506240552423e-5 6.896750413457963e-5 3.1473822353777903e-005 596/10018/7531/7532/207/10971/7533/2810/7534/7157/5599/140735/7529 13 Bluetongue_virus_10 R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 21/1301 66/10654 2.1729887750669917e-5 7.360857264232165e-5 3.3591807738015496e-5 5718/5689/5684/5682/7321/5690/5717/7316/10213/5711/5708/5692/5686/5702/6233/7311/54583/5694/5693/5691/7314 21 Bluetongue_virus_10 R-HSA-68949 Orc1 removal from chromatin 22/1301 71/10654 2.2266487572041904e-5 7.503342426620371e-5 3.424204914450523e-5 5718/5689/5684/5682/5690/5717/7316/10213/890/5711/5708/5692/5686/5702/6233/23595/7311/5694/5693/4999/5691/7314 22 Bluetongue_virus_10 R-HSA-70171 Glycolysis 22/1301 71/10654 2.2266487572041904e-5 7.503342426620371e-5 3.424204914450523e-5 23165/4928/81929/5313/2597/55706/9631/79023/57122/5214/5528/3098/9688/5519/2023/226/2821/8086/5518/6396/5515/5516 22 Bluetongue_virus_10 R-HSA-3928664 Ephrin signaling 10/1301 19/10654 2.31881668385104e-5 7.793633217930508e-5 3.556681229365505e-5 1947/1949/6714/5063/2534/1948/2048/5058/5062/5879 10 Bluetongue_virus_10 R-HSA-2172127 DAP12 interactions 16/1301 43/10654 2.3406046396458e-5 7.84648291114421e-5 3.580799571424309e-5 5295/9402/4893/6464/5290/5291/6850/2534/695/6654/2885/3932/5296/3845/3265/5879 16 Bluetongue_virus_10 R-HSA-447115 Interleukin-12 family signaling 19/1301 57/10654 2.5493284326077024e-5 8.524111089907925e-5 3.890040121563773e-5 1072/821/5908/4478/3313/3185/6774/3936/6647/5898/3717/3181/998/4001/3716/6845/375/5062/3572 19 Bluetongue_virus_10 R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 29/1301 108/10654 2.6120737847735548e-5 8.711400715198402e-5 3.975511104877819e-5 5295/7291/596/3561/207/5292/9021/7422/4582/3082/5743/301/332/3688/6774/3718/4609/3717/598/2247/3320/2335/595/7157/3716/3312/3569/3162/4170 29 Bluetongue_virus_10 R-HSA-5619084 ABC transporter disorders 23/1301 77/10654 2.8276637336281605e-5 9.406161622917325e-5 4.2925703005422755e-5 5718/5689/5684/5682/5690/91445/5717/1080/1244/7316/10213/5711/5708/5692/5686/5702/6233/7311/11160/5694/5693/5691/7314 23 Bluetongue_virus_10 R-HSA-68877 Mitotic Prometaphase 45/1301 200/10654 2.8877176396743852e-5 9.581299040355525e-5 4.37249553537741e-5 4928/81929/55143/5525/7531/10142/1459/5526/7532/9212/121441/1460/79023/9133/10381/57122/64105/5116/332/5528/5501/1457/983/9702/5519/3320/8243/9126/10426/5529/9918/10540/11004/5527/7514/9184/5518/5347/6396/25909/27229/140735/10806/5515/5516 45 Bluetongue_virus_10 R-HSA-1433559 Regulation of KIT signaling 9/1301 16/10654 3.008914132053424e-5 9.932486956319211e-5 4.532762696245894e-5 3815/5578/6714/4067/2534/6654/2885/7525/3932 9 Bluetongue_virus_10 R-HSA-399954 Sema3A PAK dependent Axon repulsion 9/1301 16/10654 3.008914132053424e-5 9.932486956319211e-5 4.532762696245894e-5 1072/5361/3320/5063/2534/3326/5058/5062/5879 9 Bluetongue_virus_10 R-HSA-399719 Trafficking of AMPA receptors 13/1301 31/10654 3.1084879558724325e-5 1.0147775992527721e-4 4.6310114144700665e-5 818/1173/815/5579/817/5578/2036/80852/9495/816/4905/1742/1739 13 Bluetongue_virus_10 R-HSA-399721 Glutamate binding, activation of AMPA receptors and synaptic plasticity 13/1301 31/10654 3.1084879558724325e-5 1.0147775992527721e-4 4.6310114144700665e-5 818/1173/815/5579/817/5578/2036/80852/9495/816/4905/1742/1739 13 Bluetongue_virus_10 R-HSA-1660499 Synthesis of PIPs at the plasma membrane 18/1301 53/10654 3.1133439482484586e-5 1.0147775992527721e-4 4.6310114144700665e-5 5295/5305/5290/5291/59339/22874/8503/146850/4534/5294/5728/59338/51552/5293/5296/8394/375/54477 18 Bluetongue_virus_10 R-HSA-191859 snRNP Assembly 18/1301 53/10654 3.1133439482484586e-5 1.0147775992527721e-4 4.6310114144700665e-5 23165/4928/81929/6633/11218/55706/9631/79023/57122/9688/51808/1207/79084/8086/6636/10419/79833/6396 18 Bluetongue_virus_10 R-HSA-194441 Metabolism of non-coding RNA 18/1301 53/10654 3.1133439482484586e-5 1.0147775992527721e-4 4.6310114144700665e-5 23165/4928/81929/6633/11218/55706/9631/79023/57122/9688/51808/1207/79084/8086/6636/10419/79833/6396 18 Bluetongue_virus_10 R-HSA-190377 FGFR2b ligand binding and activation 7/1301 10/10654 3.421056934371428e-5 1.11227328469262e-4 5.075940069247213e-5 2263/2248/2247/2255/27006/2246/2252 7 Bluetongue_virus_10 R-HSA-171007 p38MAPK events 8/1301 13/10654 3.5331539771187176e-5 1.1372888672615971e-4 5.190100500559311e-5 4893/5899/6714/5898/5603/5900/3845/3265 8 Bluetongue_virus_10 R-HSA-2995383 Initiation of Nuclear Envelope Reformation 8/1301 13/10654 3.5331539771187176e-5 1.1372888672615971e-4 5.190100500559311e-5 4000/7444/2010/4001/23592/5518/7112/5515 8 Bluetongue_virus_10 R-HSA-2995410 Nuclear Envelope Reassembly 8/1301 13/10654 3.5331539771187176e-5 1.1372888672615971e-4 5.190100500559311e-5 4000/7444/2010/4001/23592/5518/7112/5515 8 Bluetongue_virus_10 R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 8/1301 13/10654 3.5331539771187176e-5 1.1372888672615971e-4 5.190100500559311e-5 7531/7532/10971/7533/2810/7534/983/7529 8 Bluetongue_virus_10 R-HSA-68867 Assembly of the pre-replicative complex 21/1301 68/10654 3.59826324690204e-5 1.1546596259306898e-4 5.269373221728764e-5 5718/5689/5684/5682/5690/5717/7316/10213/5711/5708/5692/5686/5702/6233/23595/7311/5694/5693/4999/5691/7314 21 Bluetongue_virus_10 R-HSA-8939902 Regulation of RUNX2 expression and activity 22/1301 73/10654 3.604965138145276e-5 1.1546596259306898e-4 5.269373221728764e-5 5718/5689/7291/5684/5682/5690/5717/7316/10213/865/5711/5708/5692/5686/55294/5702/6233/7311/5694/5693/5691/7314 22 Bluetongue_virus_10 R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 10/1301 20/10654 4.1309835098924515e-5 1.3133888603933248e-4 5.993745633129874e-5 7321/8697/8881/51529/64682/29945/10393/9184/29882/996 10 Bluetongue_virus_10 R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 10/1301 20/10654 4.1309835098924515e-5 1.3133888603933248e-4 5.993745633129874e-5 7321/8697/8881/51529/64682/29945/10393/9184/29882/996 10 Bluetongue_virus_10 R-HSA-8876384 Listeria monocytogenes entry into host cells 10/1301 20/10654 4.1309835098924515e-5 1.3133888603933248e-4 5.993745633129874e-5 1499/7316/1500/4233/6714/999/6233/2885/7311/7314 10 Bluetongue_virus_10 R-HSA-5696398 Nucleotide Excision Repair 29/1301 111/10654 4.541078412670908e-5 1.4402341828421948e-4 6.572613492023684e-5 10450/9318/6118/6917/27339/5430/5436/5431/7316/64708/5426/283899/5437/5427/5985/10920/2033/2068/10987/2071/7329/6233/7311/8607/7334/57461/5432/7314/51138 29 Bluetongue_virus_10 R-HSA-3371453 Regulation of HSF1-mediated heat shock response 21/1301 69/10654 4.5854857286075847e-005 1.450762477461666e-4 6.620660130610876e-5 23165/6118/4928/81929/55706/9631/7531/5594/9530/545/79023/57122/3313/9532/9688/6767/8086/6396/3312/51182/5595 21 Bluetongue_virus_10 R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 13/1301 32/10654 4.653843645205546e-5 1.4665629589473856e-4 6.692766777592804e-5 59345/5594/409/6714/408/2783/2784/2768/2782/2776/9002/5595/2787 13 Bluetongue_virus_10 R-HSA-69481 G2/M Checkpoints 39/1301 168/10654 4.658094096811248e-5 1.4665629589473856e-4 6.692766777592804e-5 5718/6118/5689/5684/5682/7531/7486/7532/10971/5690/5717/7533/2810/545/9133/7534/580/7316/10213/983/5711/4683/5708/5692/5985/5686/5702/7157/6233/23595/7311/7334/5694/5810/5693/4999/5691/7529/7314 39 Bluetongue_virus_10 R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 17/1301 50/10654 5.062654274634776e-5 1.590066658101311e-4 7.256384895426953e-5 5718/5689/5684/5682/5690/5717/2209/10213/5711/5708/5692/5686/5702/9902/5694/5693/5691 17 Bluetongue_virus_10 R-HSA-5663220 RHO GTPases Activate Formins 34/1301 140/10654 5.365991286242797e-5 1.6812573182562178e-4 7.672540108531184e-5 4928/81929/71/55143/5525/1856/5526/9212/79023/10381/57122/64105/332/5528/3688/5501/6714/5519/5529/998/11004/5527/1855/7514/9184/5518/5347/387/6396/25909/140735/5879/5515/5516 34 Bluetongue_virus_10 R-HSA-913531 Interferon Signaling 44/1301 199/10654 5.5024350713040024e-5 1.719843232431734e-4 7.848629735574741e-5 23165/818/4928/815/3838/81929/55706/960/5770/9631/4281/3107/817/9021/2209/79023/57122/1982/7706/4684/7316/103/9688/3459/6059/3717/10612/816/8086/9246/5371/6233/5580/3716/7311/5300/9775/6396/7334/4938/5781/3105/7314/5595 44 Bluetongue_virus_10 R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 20/1301 65/10654 5.817012169073116e-5 1.8137864450073763e-4 8.277346421940441e-5 10450/6118/6917/27339/5430/5436/5431/7316/5426/5437/5427/5985/2033/2068/2071/6233/7311/57461/5432/7314 20 Bluetongue_virus_10 R-HSA-8849932 Synaptic adhesion-like molecules 10/1301 21/10654 7.025827604427112e-5 2.1854377211847793e-4 9.973404063976746e-5 2904/10211/2319/2902/2905/2903/1741/2906/1742/1739 10 Bluetongue_virus_10 R-HSA-6794361 Neurexins and neuroligins 18/1301 56/10654 7.144231615075272e-5 2.2169390191624464e-4 1.0117162529489405e-4 8573/2035/2904/2036/2902/23136/22839/57669/9369/55327/2905/2903/2037/9066/1741/2906/1742/1740 18 Bluetongue_virus_10 R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 8/1301 14/10654 7.360635611433984e-5 2.2731891363235261e-4 1.0373864032193106e-4 5594/5861/9133/26003/983/8548/5347/5595 8 Bluetongue_virus_10 R-HSA-428540 Activation of RAC1 8/1301 14/10654 7.360635611433984e-5 2.2731891363235261e-4 1.0373864032193106e-4 10298/6091/5063/6654/6655/5058/5062/5879 8 Bluetongue_virus_10 R-HSA-6782135 Dual incision in TC-NER 20/1301 66/10654 7.401370166467041e-5 2.2803269036686554e-4 1.0406437752852159e-4 10450/6118/6917/27339/5430/5436/5431/7316/5426/5437/5427/5985/2033/2068/2071/6233/7311/57461/5432/7314 20 Bluetongue_virus_10 R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 11/1301 25/10654 7.506186506298838e-5 2.301660032974099e-4 1.0503793040742452e-4 9252/5594/5528/5519/6195/6196/5518/6197/5595/5515/5516 11 Bluetongue_virus_10 R-HSA-400685 Sema4D in semaphorin signaling 11/1301 25/10654 7.506186506298838e-5 2.301660032974099e-4 1.0503793040742452e-4 4627/2909/2064/4233/4637/9475/4628/6093/10507/387/5879 11 Bluetongue_virus_10 R-HSA-437239 Recycling pathway of L1 16/1301 47/10654 8.241703552264097e-5 2.5152746218466373e-4 1.1478638760725321e-4 1173/9252/71/7430/5594/1785/10381/4478/8650/6714/26052/27330/6195/6196/24137/6197 16 Bluetongue_virus_10 R-HSA-9020591 Interleukin-12 signaling 16/1301 47/10654 8.241703552264097e-5 2.5152746218466373e-4 1.1478638760725321e-4 1072/5908/4478/3313/3185/3936/6647/5898/3717/3181/998/4001/3716/6845/375/5062 16 Bluetongue_virus_10 R-HSA-1059683 Interleukin-6 signaling 7/1301 11/10654 8.412966934508479e-5 2.555488078228632e-4 1.1662155795056233e-4 9021/6774/3717/3716/5781/3569/3572 7 Bluetongue_virus_10 R-HSA-8875555 MET activates RAP1 and RAC1 7/1301 11/10654 8.412966934508479e-5 2.555488078228632e-4 1.1662155795056233e-4 5908/3082/4233/2885/5906/2549/5879 7 Bluetongue_virus_10 R-HSA-4791275 Signaling by WNT in cancer 13/1301 34/10654 9.826865232161095e-5 2.977977426327039e-4 1.3590216677535747e-4 1499/5525/5526/1452/5528/5519/5529/5527/4040/79412/5518/5515/5516 13 Bluetongue_virus_10 R-HSA-168325 Viral Messenger RNA Synthesis 15/1301 43/10654 9.967605305086039e-5 3.0135703889676014e-4 1.3752647752467457e-4 23165/4928/81929/55706/9631/5430/5436/79023/57122/5431/9688/5437/8086/6396/5432 15 Bluetongue_virus_10 R-HSA-418597 G alpha (z) signalling events 16/1301 48/10654 1.0977150953714555e-4 3.3110567212369773e-4 1.5110248276368213e-4 5579/59345/2770/5578/112/114/2778/2783/2784/2782/2771/5580/5581/115/2773/2787 16 Bluetongue_virus_10 R-HSA-162599 Late Phase of HIV Life Cycle 33/1301 139/10654 1.102094242934302e-4 3.3165347682720625e-4 1.5135247742622854e-4 23165/4928/6917/81929/55706/79643/9631/5430/5436/79023/57122/91782/5431/7316/6872/9688/23327/5437/89853/83860/2068/2071/5902/8086/6233/7514/7311/93343/11198/6396/2961/5432/7314 33 Bluetongue_virus_10 R-HSA-389357 CD28 dependent PI3K/Akt signaling 10/1301 22/10654 1.1476721865642178e-4 3.4456793721904824e-4 1.5724608539810142e-4 5295/5290/207/8503/2534/79109/2475/3932/5296/253260 10 Bluetongue_virus_10 R-HSA-917937 Iron uptake and transport 18/1301 58/10654 1.1921105117826358e-4 3.5708125052007656e-4 1.6295662697613517e-4 28982/55240/9550/9114/3163/9843/7316/3658/527/7037/245972/55832/4891/6233/7311/3162/51382/7314 18 Bluetongue_virus_10 R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 32/1301 134/10654 1.2378847786126705e-4 3.699360054329782e-4 1.688229879182468e-4 5099/351/1072/5579/3674/7094/7422/5578/3082/7414/10490/334/1950/51706/308/6647/7273/226/2244/2335/3690/2/94121/10487/88/2266/5155/2243/7450/29789/801/6814 32 Bluetongue_virus_10 R-HSA-390466 Chaperonin-mediated protein folding 25/1301 95/10654 1.3123305233774083e-4 3.912801145738171e-4 1.7856352743505366e-4 10694/59345/1459/2770/5204/10528/1460/10381/2779/7203/10576/6774/1457/55294/2783/2784/55135/2782/7157/2771/10574/22948/8877/2773/2787 25 Bluetongue_virus_10 R-HSA-162587 HIV Life Cycle 35/1301 152/10654 1.3308271771891444e-4 3.9588284305350636e-4 1.806640160685082e-4 23165/4928/6917/81929/55706/79643/9631/5430/5436/7520/79023/57122/91782/5431/7316/6872/9688/23327/5437/89853/83860/2068/2071/5902/8086/6233/7514/7311/93343/11198/6396/2547/2961/5432/7314 35 Bluetongue_virus_10 R-HSA-9615710 Microautophagy 13/1301 35/10654 1.3901295497982985e-4 4.125751462016051e-4 1.882816700716672e-4 79643/1080/5116/91782/7316/89853/123/6233/7311/200894/93343/3312/7314 13 Bluetongue_virus_10 R-HSA-4419969 Depolymerisation of the Nuclear Lamina 8/1301 15/10654 1.4085348174581463e-4 4.170810191741056e-4 1.9033795798964714e-4 4000/5579/5578/983/2010/4001/23592/7112 8 Bluetongue_virus_10 R-HSA-391251 Protein folding 26/1301 101/10654 1.43724953093395e-4 4.2461207603391126e-4 1.9377481058734585e-4 10694/59345/1459/2770/5204/10528/1460/10381/2779/7203/10576/6774/1457/55294/2783/2784/55135/2782/7157/2771/10574/22948/8877/6904/2773/2787 26 Bluetongue_virus_10 R-HSA-141424 Amplification of signal from the kinetochores 25/1301 96/10654 1.572311756823938e-4 4.624025939386763e-4 2.1102078841584432e-4 4928/81929/55143/5525/5526/9212/79023/57122/64105/332/5528/5501/5519/5529/11004/5527/7514/9184/5518/5347/6396/25909/140735/5515/5516 25 Bluetongue_virus_10 R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 25/1301 96/10654 1.572311756823938e-4 4.624025939386763e-4 2.1102078841584432e-4 4928/81929/55143/5525/5526/9212/79023/57122/64105/332/5528/5501/5519/5529/11004/5527/7514/9184/5518/5347/6396/25909/140735/5515/5516 25 Bluetongue_virus_10 R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 9/1301 19/10654 1.72355304570324e-4 5.057318914149642e-4 2.307944286047303e-4 7321/8697/8881/51529/64682/29945/10393/29882/996 9 Bluetongue_virus_10 R-HSA-4615885 SUMOylation of DNA replication proteins 15/1301 45/10654 1.7902951380836343e-4 5.238062899754693e-4 2.390428119061566e-4 23165/4928/81929/55706/55143/9631/9212/79023/57122/332/6790/9688/8086/7329/6396 15 Bluetongue_virus_10 R-HSA-2029481 FCGR activation 7/1301 12/10654 1.805992798879936e-4 5.238062899754693e-4 2.390428119061566e-4 2209/3055/6850/6714/4067/2534/7525 7 Bluetongue_virus_10 R-HSA-210990 PECAM1 interactions 7/1301 12/10654 1.805992798879936e-4 5.238062899754693e-4 2.390428119061566e-4 6714/4067/2534/3690/7525/3932/5781 7 Bluetongue_virus_10 R-HSA-112409 RAF-independent MAPK1/3 activation 10/1301 23/10654 1.8094390387869767e-4 5.238062899754693e-4 2.390428119061566e-4 5604/5594/983/5605/3717/3716/5781/3569/3572/5595 10 Bluetongue_virus_10 R-HSA-373753 Nephrin family interactions 10/1301 23/10654 1.8094390387869767e-4 5.238062899754693e-4 2.390428119061566e-4 5295/8573/6711/5290/5291/2534/6709/88/8826/5296 10 Bluetongue_virus_10 R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 10/1301 23/10654 1.8094390387869767e-4 5.238062899754693e-4 2.390428119061566e-4 5601/7316/5602/7189/5609/6233/7311/5599/7334/7314 10 Bluetongue_virus_10 R-HSA-425393 Transport of inorganic cations/anions and amino acids/oligopeptides 27/1301 108/10654 1.8310469423499988e-4 5.288782909377006e-4 2.4135745645167985e-4 6507/6510/6574/6533/23315/6560/9498/8140/54407/81539/6541/10723/1497/1836/8501/6520/65010/23657/6575/6522/6558/6542/6548/9497/801/55117/6564 27 Bluetongue_virus_10 R-HSA-177243 Interactions of Rev with host cellular proteins 13/1301 36/10654 1.934947824000593e-4 5.576442058478323e-4 2.5448499103606444e-4 23165/4928/81929/55706/9631/4869/79023/57122/9688/5902/8086/7514/6396 13 Bluetongue_virus_10 R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 24/1301 92/10654 2.0527762529992574e-4 5.902872158624531e-4 2.6938186618306046e-4 6118/1459/7486/9212/1460/545/580/7316/6872/890/1457/6790/4683/83860/6794/5985/7157/6233/7311/5300/11198/5810/26155/7314 24 Bluetongue_virus_10 R-HSA-2500257 Resolution of Sister Chromatid Cohesion 30/1301 126/10654 2.1053705066430373e-4 6.040686109969159e-4 2.756711061329779e-4 4928/81929/55143/5525/5526/9212/79023/9133/10381/57122/64105/332/5528/5501/983/5519/8243/9126/5529/11004/5527/7514/9184/5518/5347/6396/25909/140735/5515/5516 30 Bluetongue_virus_10 R-HSA-8875878 MET promotes cell motility 14/1301 41/10654 2.193229807844037e-4 6.278848166703947e-4 2.8653980489066257e-4 5747/5908/3082/3688/4233/6714/1281/3673/2335/64759/2885/5906/2549/5879 14 Bluetongue_virus_10 R-HSA-205043 NRIF signals cell death from the nucleus 8/1301 16/10654 2.5161782217109595e-4 7.171662156154145e-4 3.272840209552164e-4 8878/7316/7189/6233/7311/5599/5663/7314 8 Bluetongue_virus_10 R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 8/1301 16/10654 2.5161782217109595e-4 7.171662156154145e-4 3.272840209552164e-4 5590/50848/7316/6233/7311/56288/387/7314 8 Bluetongue_virus_10 R-HSA-3371571 HSF1-dependent transactivation 10/1301 24/10654 2.7646022084558305e-4 7.827998375802723e-4 3.572364019218521e-4 818/815/817/3320/2033/816/3326/2475/3312/57521 10 Bluetongue_virus_10 R-HSA-5627123 RHO GTPases activate PAKs 10/1301 24/10654 2.7646022084558305e-4 7.827998375802723e-4 3.572364019218521e-4 4627/4771/4637/5063/998/4628/5058/801/5062/5879 10 Bluetongue_virus_10 R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 10/1301 24/10654 2.7646022084558305e-4 7.827998375802723e-4 3.572364019218521e-4 5590/27035/5579/5578/5594/6279/5580/5300/5879/5595 10 Bluetongue_virus_10 R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 59/1301 309/10654 2.7750407817829726e-4 7.840399064688137e-4 3.5780231638249773e-4 5718/5689/8945/5684/64410/5682/26046/7321/9021/8697/5690/7174/5717/10533/8881/8452/23376/7316/10213/7317/54926/4008/5711/23327/51465/5708/5692/5686/89910/55521/25898/55294/7328/5702/83737/51529/9040/10075/64682/29945/9246/10393/80176/6233/56658/4012/7311/9320/29882/7334/92591/5930/5694/84961/29116/5693/5691/7314/996 59 Bluetongue_virus_10 R-HSA-1489509 DAG and IP3 signaling 14/1301 42/10654 2.9244935278856953e-4 8.244650599311742e-4 3.762506293186275e-4 818/815/3838/817/5578/112/114/5573/10768/816/5580/5581/115/801 14 Bluetongue_virus_10 R-HSA-6798695 Neutrophil degranulation 84/1301 480/10654 3.487367008135775e-4 9.805223661718677e-4 4.474685165723728e-4 10450/10694/5718/8773/58485/5689/8804/4893/9218/4790/960/4332/56888/10159/1938/57826/1915/3107/8876/23197/79888/5594/3163/7520/5717/5908/6727/7414/1460/10533/3958/10213/10576/6278/527/102/6279/6515/4048/4973/6286/5870/5795/6793/226/140885/2821/55832/5708/3320/5686/3482/3728/5873/5702/9961/10788/51552/10075/10487/22875/3326/5580/6709/55004/10097/23191/6093/8826/5906/9522/387/196527/3312/2040/2547/8673/10493/23250/10970/5663/51382/1654/5879 84 Bluetongue_virus_10 R-HSA-202670 ERKs are inactivated 7/1301 13/10654 3.5007831002426806e-4 9.805223661718677e-4 4.474685165723728e-4 5594/5528/5519/5518/5595/5515/5516 7 Bluetongue_virus_10 R-HSA-209543 p75NTR recruits signalling complexes 7/1301 13/10654 3.5007831002426806e-4 9.805223661718677e-4 4.474685165723728e-4 5584/8878/7316/7189/6233/7311/7314 7 Bluetongue_virus_10 R-HSA-111465 Apoptotic cleavage of cellular proteins 13/1301 38/10654 3.586892122609589e-4 9.981587971304965e-4 4.5551703017181205e-4 4000/22985/1499/5747/118/1829/100506658/10134/999/4001/5580/6709/6093 13 Bluetongue_virus_10 R-HSA-111996 Ca-dependent events 13/1301 38/10654 3.586892122609589e-4 9.981587971304965e-4 4.5551703017181205e-4 818/815/3838/817/5578/5594/112/114/5573/816/5580/115/801 13 Bluetongue_virus_10 R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 13/1301 38/10654 3.586892122609589e-4 9.981587971304965e-4 4.5551703017181205e-4 1072/5908/4478/3313/3185/3936/6647/5898/3181/998/4001/375/5062 13 Bluetongue_virus_10 R-HSA-71291 Metabolism of amino acids and derivatives 68/1301 372/10654 3.6647829158944123e-4 0.001017645728147504 4.6441003293805404e-4 5718/5689/6138/6144/6203/5684/6194/6234/6191/6128/5682/6132/6147/6129/4143/6222/6152/5690/6136/6125/5717/11185/6224/6146/6154/6141/6134/60678/6160/10213/7299/8140/6205/6165/6142/9061/5711/162417/5708/5692/5686/6156/6235/6124/5702/26227/6207/6139/6520/6233/7311/6223/6188/6135/5860/36/6161/5694/6187/6168/5693/6208/6157/5691/200916/6535/6122/6230 68 Bluetongue_virus_10 R-HSA-186797 Signaling by PDGF 17/1301 58/10654 3.917453349936452e-4 0.001085478508526289 4.95366015849059e-4 5295/4893/5290/5291/5921/6774/6714/1281/5159/6654/2885/5155/5296/3845/3265/5781/5156 17 Bluetongue_virus_10 R-HSA-191273 Cholesterol biosynthesis 10/1301 25/10654 4.107257913673148e-4 0.0011332178550731457 5.171522140210159e-4 3930/9453/3156/4597/1717/1595/6309/50814/2224/10654 10 Bluetongue_virus_10 R-HSA-2029485 Role of phospholipids in phagocytosis 10/1301 25/10654 4.107257913673148e-4 0.0011332178550731457 5.171522140210159e-4 5295/5290/23646/5291/2209/6850/10768/5580/5296/5581 10 Bluetongue_virus_10 R-HSA-165054 Rev-mediated nuclear export of HIV RNA 12/1301 34/10654 4.3395871766706057e-4 0.0011947714482152688 5.452426441460716e-4 23165/4928/81929/55706/9631/79023/57122/9688/5902/8086/7514/6396 12 Bluetongue_virus_10 R-HSA-6807004 Negative regulation of MET activity 9/1301 21/10654 4.365613617989135e-4 0.0011993851426067813 5.473481371531802e-4 5770/3082/7316/4233/5795/6233/2885/7311/7314 9 Bluetongue_virus_10 R-HSA-450341 Activation of the AP-1 family of transcription factors 6/1301 10/10654 4.4451087854416684e-4 0.0012160614732265368 5.549585019768055e-4 3725/5601/5594/5602/5599/5595 6 Bluetongue_virus_10 R-HSA-8875656 MET receptor recycling 6/1301 10/10654 4.4451087854416684e-4 0.0012160614732265368 5.549585019768055e-4 3082/382/4233/2885/23163/2549 6 Bluetongue_virus_10 R-HSA-70326 Glucose metabolism 23/1301 91/10654 4.5292239885272274e-4 0.0012364590382181926 5.642670791836053e-4 23165/4928/81929/5313/2597/55706/9631/79023/57122/5214/5528/3098/9688/5519/2023/226/2821/8086/5518/4191/6396/5515/5516 23 Bluetongue_virus_10 R-HSA-193704 p75 NTR receptor-mediated signalling 24/1301 97/10654 4.82008081456167e-4 0.0013130914892721685 5.992388558380272e-4 445328/4790/5584/10018/7531/57580/8878/7074/9459/7316/5970/4792/7189/6654/6233/7311/26084/387/6655/5599/5924/5663/7314/5879 24 Bluetongue_virus_10 R-HSA-69231 Cyclin D associated events in G1 14/1301 44/10654 5.027237836408773e-4 0.0013637831782626734 6.22372376966859e-4 1019/1029/7316/6714/5519/4067/3717/595/6233/7311/5518/7314/5515/5516 14 Bluetongue_virus_10 R-HSA-69236 G1 Phase 14/1301 44/10654 5.027237836408773e-4 0.0013637831782626734 6.22372376966859e-4 1019/1029/7316/6714/5519/4067/3717/595/6233/7311/5518/7314/5515/5516 14 Bluetongue_virus_10 R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 12/1301 35/10654 5.878434634169188e-4 0.0015913586645637926 7.262281060931325e-4 23165/4928/81929/55706/9631/79023/9133/57122/983/9688/8086/6396 12 Bluetongue_virus_10 R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 26/1301 110/10654 6.106660967259428e-4 0.0016496908750801046 7.528484348165125e-4 3725/1019/4790/1029/7321/8697/5594/8881/7316/890/6774/5970/6195/51529/64682/29945/10393/6233/6196/7311/6197/29882/3569/7314/996/5595 26 Bluetongue_virus_10 R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 7/1301 14/10654 6.265502639341962e-4 0.001689075086522604 7.708217062874651e-4 4893/2909/5921/387/3845/3265/5879 7 Bluetongue_virus_10 R-HSA-5205685 Pink/Parkin Mediated Mitophagy 9/1301 22/10654 6.593419224360213e-4 0.001773780556407924 8.094776638288827e-4 65018/8878/7316/56993/55669/6233/9804/7311/7314 9 Bluetongue_virus_10 R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 11/1301 31/10654 7.113488090289379e-4 0.0019018292538914166 8.679136186716707e-4 23165/4928/81929/55706/9631/79023/57122/9688/8086/7514/6396 11 Bluetongue_virus_10 R-HSA-182971 EGFR downregulation 11/1301 31/10654 7.113488090289379e-4 0.0019018292538914166 8.679136186716707e-4 1839/685/2069/7316/1950/998/6233/2885/7311/1956/7314 11 Bluetongue_virus_10 R-HSA-2122948 Activated NOTCH1 Transmits Signal to the Nucleus 11/1301 31/10654 7.113488090289379e-4 0.0019018292538914166 8.679136186716707e-4 409/7316/8650/102/408/83737/6233/7311/4851/5663/7314 11 Bluetongue_virus_10 R-HSA-114608 Platelet degranulation 29/1301 129/10654 7.341201419574451e-4 0.0019586628117380083 8.938500263442795e-4 5099/351/1072/3674/7094/7422/3082/7414/10490/334/1950/51706/308/6647/7273/226/2244/2335/3690/2/94121/10487/88/2266/5155/2243/7450/29789/801 29 Bluetongue_virus_10 R-HSA-111933 Calmodulin induced events 12/1301 36/10654 7.850178039253502e-4 0.0020858583948242366 9.518966562241898e-4 818/815/3838/817/5578/112/114/5573/816/5580/115/801 12 Bluetongue_virus_10 R-HSA-111997 CaM pathway 12/1301 36/10654 7.850178039253502e-4 0.0020858583948242366 9.518966562241898e-4 818/815/3838/817/5578/112/114/5573/816/5580/115/801 12 Bluetongue_virus_10 R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 15/1301 51/10654 8.153715874403361e-4 0.0021620713814503993 9.866770072347467e-4 5718/5689/5684/5682/5690/5717/10213/5711/5708/5692/5686/5702/5694/5693/5691 15 Bluetongue_virus_10 R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 13/1301 41/10654 8.218774730827165e-4 0.0021748659512659204 9.925159022697323e-4 23165/4928/81929/55706/9631/29894/79023/57122/81608/9688/10482/8086/6396 13 Bluetongue_virus_10 R-HSA-68875 Mitotic Prophase 31/1301 142/10654 8.290459141733571e-4 0.002189357985592498 9.991294475859363e-4 4000/23165/4928/81929/55706/5579/9631/5578/5594/5861/79023/9133/57122/26003/983/8548/9688/5519/7444/8086/2010/4001/79648/23592/5518/5347/6396/7112/5595/5515/5516 31 Bluetongue_virus_10 R-HSA-2514853 Condensation of Prometaphase Chromosomes 6/1301 11/10654 8.769683295830645e-4 0.002301819510102405 0.0010504520826221826 1459/1460/9133/1457/983/9918 6 Bluetongue_virus_10 R-HSA-2586552 Signaling by Leptin 6/1301 11/10654 8.769683295830645e-4 0.002301819510102405 0.0010504520826221826 3667/9021/6774/3717/8660/5781 6 Bluetongue_virus_10 R-HSA-9614399 Regulation of localization of FOXO transcription factors 6/1301 11/10654 8.769683295830645e-4 0.002301819510102405 0.0010504520826221826 7532/207/10971/2810/7534/7529 6 Bluetongue_virus_10 R-HSA-6807878 COPI-mediated anterograde transport 24/1301 101/10654 8.986000567689483e-4 0.002353822820767245 0.0010741841718461113 11070/6711/6712/5861/10381/9570/832/57731/6710/8775/11316/9527/10972/10540/6708/4905/287/6709/51332/375/140735/10959/10652/51164 24 Bluetongue_virus_10 R-HSA-1483255 PI Metabolism 21/1301 84/10654 9.18570348367405e-4 0.0024012727894695395 0.0010958383103330447 5295/5305/5290/5297/5291/59339/22874/8503/146850/4534/6305/5294/5728/54893/59338/51552/5293/5296/8394/375/54477 21 Bluetongue_virus_10 R-HSA-1251985 Nuclear signaling by ERBB4 11/1301 32/10654 9.657970957045549e-4 0.0025095209675536022 0.001145238154069447 1839/685/2069/10413/6714/145957/3084/2066/9542/10718/5663 11 Bluetongue_virus_10 R-HSA-451326 Activation of kainate receptors upon glutamate binding 11/1301 32/10654 9.657970957045549e-4 0.0025095209675536022 0.001145238154069447 5331/59345/23236/2783/2784/2782/1741/1742/1739/801/2787 11 Bluetongue_virus_10 R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 11/1301 32/10654 9.657970957045549e-4 0.0025095209675536022 0.001145238154069447 5295/6850/10768/4067/2534/695/6654/2885/5293/801/6786 11 Bluetongue_virus_10 R-HSA-6784531 tRNA processing in the nucleus 16/1301 57/10654 9.706164911067543e-4 0.0025169894579000806 0.0011486464539835232 60528/23165/4928/81929/55706/9631/29894/79023/57122/10978/11260/9688/8086/1653/6396/51493 16 Bluetongue_virus_10 R-HSA-75153 Apoptotic execution phase 15/1301 52/10654 0.0010186900364701685 0.002636369814384796 0.0012031265483363465 4000/22985/1499/5747/10059/118/1829/100506658/10134/999/4001/5580/6709/6093/5062 15 Bluetongue_virus_10 R-HSA-4570464 SUMOylation of RNA binding proteins 14/1301 47/10654 0.0010507858545234971 0.0027051415967468107 0.001234511051635045 23165/4928/81929/55706/9631/51602/79023/57122/3183/3190/9688/8086/7329/6396 14 Bluetongue_virus_10 R-HSA-937039 IRAK1 recruits IKK complex 7/1301 15/10654 0.0010515349483490306 0.0027051415967468107 0.001234511051635045 246330/7316/7189/6233/7311/7334/7314 7 Bluetongue_virus_10 R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 7/1301 15/10654 0.0010515349483490306 0.0027051415967468107 0.001234511051635045 246330/7316/7189/6233/7311/7334/7314 7 Bluetongue_virus_10 R-HSA-8851708 Signaling by FGFR2 IIIa TM 8/1301 19/10654 0.001054237967191079 0.0027067141459231276 0.0012352286958943095 5430/5436/5431/2263/5437/2247/2246/5432 8 Bluetongue_virus_10 R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 13/1301 42/10654 0.001059207320111126 0.002708723858149796 0.0012361458426926185 23165/4928/81929/55706/9631/29894/79023/57122/81608/9688/10482/8086/6396 13 Bluetongue_virus_10 R-HSA-2426168 Activation of gene expression by SREBF (SREBP) 13/1301 42/10654 0.001059207320111126 0.002708723858149796 0.0012361458426926185 79718/6319/9453/3156/4597/1717/1595/4801/10498/6309/2224/31/10654 13 Bluetongue_virus_10 R-HSA-2559583 Cellular Senescence 39/1301 195/10654 0.001174340112799841 0.0029972309782307577 0.0013678081662632843 3725/25913/1019/5601/4790/9448/1029/7321/2146/8697/5594/50488/8881/7316/890/6774/5970/4683/5602/6195/7157/51529/4001/64682/29945/10393/5609/6233/6196/7311/57634/6197/29882/5599/3569/7314/996/5595/23043 39 Bluetongue_virus_10 R-HSA-5628897 TP53 Regulates Metabolic Genes 21/1301 86/10654 0.0012708310149162627 0.0032371167978378817 0.0014772818055698786 7531/7532/207/10971/1345/7533/2810/7534/54205/2821/5728/7157/10542/1349/2475/55004/1340/64121/57521/7248/7529 21 Bluetongue_virus_10 R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 11/1301 33/10654 0.001290955708019564 0.00326268884019007 0.0014889517931722359 23165/4928/81929/55706/9631/79023/57122/9688/8086/7514/6396 11 Bluetongue_virus_10 R-HSA-180746 Nuclear import of Rev protein 11/1301 33/10654 0.001290955708019564 0.00326268884019007 0.0014889517931722359 23165/4928/81929/55706/9631/4869/79023/57122/9688/8086/6396 11 Bluetongue_virus_10 R-HSA-352230 Amino acid transport across the plasma membrane 11/1301 33/10654 0.001290955708019564 0.00326268884019007 0.0014889517931722359 6510/6533/8140/54407/81539/6541/8501/6520/23657/6542/55117 11 Bluetongue_virus_10 R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 11/1301 33/10654 0.001290955708019564 0.00326268884019007 0.0014889517931722359 351/4790/7316/5970/4792/177/7189/6233/7311/7334/7314 11 Bluetongue_virus_10 R-HSA-3232142 SUMOylation of ubiquitinylation proteins 12/1301 38/10654 0.0013463838769231446 0.003396141787014716 0.001549854016525873 23165/4928/81929/55706/9631/79023/57122/9688/8086/7329/5371/6396 12 Bluetongue_virus_10 R-HSA-982772 Growth hormone receptor signaling 9/1301 24/10654 0.0013811374767635353 0.0034770270329416626 0.001586766587066032 3667/5770/9021/5594/6774/4067/3717/8660/5595 9 Bluetongue_virus_10 R-HSA-5627117 RHO GTPases Activate ROCKs 8/1301 20/10654 0.0015706803952871809 0.003937908256839276 0.0017970930871933897 1072/4627/4637/9475/4628/6093/387/5058 8 Bluetongue_virus_10 R-HSA-8964616 G beta:gamma signalling through CDC42 8/1301 20/10654 0.0015706803952871809 0.003937908256839276 0.0017970930871933897 59345/9459/2783/2784/2782/998/5058/2787 8 Bluetongue_virus_10 R-HSA-111932 CaMK IV-mediated phosphorylation of CREB 6/1301 12/10654 0.001573337379278134 0.003937908256839276 0.0017970930871933897 818/815/3838/817/816/801 6 Bluetongue_virus_10 R-HSA-204998 Cell death signalling via NRAGE, NRIF and NADE 19/1301 76/10654 0.0015802389092172894 0.003947546618778325 0.0018014916237978041 445328/10018/7531/57580/8878/7074/9459/7316/7189/6654/6233/7311/26084/6655/5599/5924/5663/7314/5879 19 Bluetongue_virus_10 R-HSA-199977 ER to Golgi Anterograde Transport 32/1301 154/10654 0.0016446139771374786 0.004100444097140457 0.001871267500606684 10113/23256/58485/11070/6711/6712/5861/10381/9554/9570/832/57731/3998/6710/8775/11316/9527/10972/10540/51693/6708/4905/287/6709/51332/5537/6396/375/140735/10959/10652/51164 32 Bluetongue_virus_10 R-HSA-392517 Rap1 signalling 7/1301 16/10654 0.00167369271315409 0.004156925855703249 0.0018970433621162634 5908/7534/10125/5894/10235/5906/7529 7 Bluetongue_virus_10 R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 7/1301 16/10654 0.00167369271315409 0.004156925855703249 0.0018970433621162634 8945/4790/5604/7316/6233/7311/7314 7 Bluetongue_virus_10 R-HSA-159227 Transport of the SLBP independent Mature mRNA 11/1301 34/10654 0.001700823833840319 0.0042081568661364675 0.0019204230065098503 23165/4928/81929/55706/9631/79023/57122/9688/10482/8086/6396 11 Bluetongue_virus_10 R-HSA-4085377 SUMOylation of SUMOylation proteins 11/1301 34/10654 0.001700823833840319 0.0042081568661364675 0.0019204230065098503 23165/4928/81929/55706/9631/79023/57122/9688/8086/7329/6396 11 Bluetongue_virus_10 R-HSA-418346 Platelet homeostasis 21/1301 88/10654 0.0017327315444279046 0.004278921027652116 0.0019527167465328537 5525/59345/5526/5528/2778/5519/493/490/2783/2784/5529/2782/5527/5518/801/5781/4842/5515/6786/2787/5516 21 Bluetongue_virus_10 R-HSA-9006931 Signaling by Nuclear Receptors 54/1301 299/10654 0.0018768526960609763 0.004625995026100768 0.0021111064912084365 5295/3725/3838/596/5590/1839/4893/6464/685/5290/79718/6319/5747/59345/5430/2770/207/5436/5594/2069/3315/5431/1950/865/6714/4609/8503/5437/3320/2033/8243/9126/595/2783/2784/2782/2066/2771/10498/3326/7514/1956/5536/5296/3845/3265/801/29116/8877/5432/3480/2773/5595/2787 54 Bluetongue_virus_10 R-HSA-8878171 Transcriptional regulation by RUNX1 45/1301 239/10654 0.0018812299764700488 0.00462796880143012 0.0021120072379421603 55904/5718/5689/5684/3562/8861/1437/5579/5682/1459/3674/9021/5690/5717/5929/1460/3958/100506658/7316/10213/865/1457/10413/6714/5711/3558/8289/5708/5692/5686/2033/595/5702/83737/5371/57492/6233/7311/5694/3559/5781/5693/4297/5691/7314 45 Bluetongue_virus_10 R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 15/1301 55/10654 0.0019013994331047287 0.004668711321513319 0.0021306003834450278 596/351/4790/7316/5970/24145/598/5603/83737/7189/6233/3326/7311/7334/7314 15 Bluetongue_virus_10 R-HSA-392451 G beta:gamma signalling through PI3Kgamma 9/1301 25/10654 0.0019269940497989055 0.004704774151773177 0.002147057918445255 59345/207/146850/5294/2783/2784/2782/387/2787 9 Bluetongue_virus_10 R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 9/1301 25/10654 0.0019269940497989055 0.004704774151773177 0.002147057918445255 9133/890/983/5519/7514/5518/5347/5515/5516 9 Bluetongue_virus_10 R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus 9/1301 25/10654 0.0019269940497989055 0.004704774151773177 0.002147057918445255 4904/7316/1950/102/6233/7311/1956/5663/7314 9 Bovine_viral_diarrhea_virus R-HSA-72172 mRNA Splicing 184/865 191/10654 8.483011180345475e-198 1.0340790628841134e-194 5.375550242703133e-195 10450/2962/7536/51690/10921/10898/22938/29894/1993/8449/27238/1665/55749/11017/51503/988/22827/3178/10286/23451/53981/6637/199746/23450/10236/23524/2963/56949/5437/10250/6635/53938/6629/5441/6634/5434/5440/4670/10914/23020/5094/6633/10569/220988/55599/51593/6432/8683/51691/6431/9775/23658/3192/10189/3183/5438/85313/10084/6430/79622/6632/51340/9716/5431/6434/10283/9092/51362/6627/55110/54883/9295/5093/24148/22794/6936/154007/81608/5435/10946/8896/6427/10594/4686/9785/8189/23398/83443/6625/3312/10465/84844/5433/6631/10713/27339/8175/51645/10949/5356/51692/11338/55660/11051/6426/3181/84950/5439/1655/10421/9343/55954/11193/3188/51729/3185/9129/1660/55696/4116/23350/5430/25949/84991/3190/10907/10291/5432/1477/23283/10978/79869/85437/22916/9416/65109/9939/6626/11066/4904/11157/5436/5546/56259/2521/5725/1479/26121/9879/22826/11100/10081/51639/51585/3191/10285/10523/285755/6429/1478/6428/10772/9410/6638/24144/57819/57794/10992/11325/55339/9128/57703/10262/10181/6628/27316/6636/27258/8233/3184/3187/1994/8106/25804 184 Bovine_viral_diarrhea_virus R-HSA-72163 mRNA Splicing - Major Pathway 176/865 183/10654 1.84972120767781e-188 1.1274050760796252e-185 5.860695615905483e-186 10450/2962/7536/51690/10921/10898/22938/29894/1993/8449/27238/1665/55749/11017/51503/988/22827/3178/10286/23451/53981/6637/199746/23450/10236/23524/2963/56949/5437/10250/6635/53938/6629/5441/6634/5434/5440/4670/10914/23020/5094/6633/10569/220988/51593/6432/8683/51691/6431/9775/23658/3192/10189/3183/5438/85313/10084/6430/6632/51340/9716/5431/6434/10283/9092/51362/6627/55110/54883/9295/5093/24148/22794/6936/81608/5435/10946/8896/6427/10594/4686/9785/8189/23398/83443/6625/3312/10465/84844/5433/6631/10713/27339/8175/51645/10949/5356/51692/11338/55660/11051/6426/3181/84950/5439/1655/10421/9343/11193/3188/51729/3185/9129/1660/55696/4116/23350/5430/25949/84991/3190/10907/10291/5432/1477/23283/10978/79869/22916/9416/65109/9939/6626/4904/11157/5436/5546/56259/2521/5725/1479/26121/9879/22826/11100/51639/51585/3191/10285/10523/285755/6429/1478/6428/10772/9410/6638/24144/57819/57794/10992/11325/55339/9128/57703/10262/10181/6628/27316/6636/27258/3184/3187/1994/8106/25804 176 Bovine_viral_diarrhea_virus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 189/865 244/10654 5.276197311797309e-162 2.143894841026973e-159 1.1144809760357827e-159 10450/2962/7536/51690/10921/10898/22938/29894/1993/8449/27238/1665/55749/11017/51503/988/22827/3178/10286/9883/23451/53981/7919/6637/199746/23450/10236/23524/2963/56949/5437/10250/6635/53938/6629/5441/6634/5434/5440/4670/10914/23020/5094/6633/10569/220988/55599/51593/6432/8683/51691/6431/9775/23658/3192/10189/3183/5438/85313/10084/6430/79622/6632/51340/9716/5431/6434/10283/9092/51362/6627/55110/54883/9295/5093/24148/22794/6936/154007/81608/5435/10946/8896/6427/10594/4686/9785/7884/8189/23398/83443/6625/3312/10465/84844/5433/6631/10713/27339/8175/51645/10949/5356/51692/11338/55660/11051/6426/3181/84950/5439/1655/10421/9343/55954/11193/3188/51729/3185/9129/1660/55696/4116/23350/5430/25949/84991/3190/10907/10291/5432/1477/23283/10978/79869/85437/22916/9416/65109/9939/6626/56339/11066/4904/11157/5436/5546/56259/2521/5725/1479/26121/9879/22826/11100/10081/51639/51585/3191/10285/10523/285755/6429/1478/6428/10772/9410/6638/24144/57819/57794/10992/57721/11325/55339/9128/57703/10262/10181/6628/27316/6636/27258/8233/3184/3187/1994/8106/25804 189 Bovine_viral_diarrhea_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 82/865 101/10654 3.778716935350364e-72 1.1515639860480234e-69 5.986283144949788e-70 7322/5716/9491/5715/8454/6500/23198/1147/5718/7311/5711/5971/5689/5170/5701/8945/23118/10892/5688/143471/5706/5687/5705/5684/23291/841/10197/8517/5720/5685/5683/5698/5708/5692/5686/4790/5713/6885/5682/7334/7316/10213/5709/5694/5699/3551/5695/5710/801/5700/10454/7321/122706/5707/9020/5702/7335/5970/4792/5693/6850/9040/5721/84433/5696/997/5719/5691/8915/4791/5714/7189/5690/3553/6714/7314/5704/6233/5717/257397/9861/5580 82 Bovine_viral_diarrhea_virus R-HSA-1169091 Activation of NF-kappaB in B cells 66/865 67/10654 6.341024284084647e-72 1.545941720459837e-69 8.036413934776753e-70 5716/9491/5715/8454/6500/23198/1147/5718/7311/5711/5689/5701/8945/10892/5688/143471/5706/5687/5705/5684/23291/10197/8517/5720/5685/4794/5683/5698/5708/5692/5686/4790/5713/6885/5579/5966/5682/7316/10213/5709/5694/5699/3551/5695/5710/5700/122706/5707/5702/5970/4792/5693/5721/84433/5696/5719/4793/5691/8915/5714/5690/7314/5704/6233/5717/9861 66 Bovine_viral_diarrhea_virus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 104/865 171/10654 2.28987729237059e-70 4.652267365666248e-68 2.4184318070299922e-68 5716/9491/5715/6142/23198/10921/6158/5718/7311/5711/25873/5689/6154/6138/5701/6141/26986/5688/6202/143471/6228/5706/23521/5687/6203/5705/5684/9349/10197/3921/5720/6188/5685/6189/9775/6194/5683/6134/5698/5708/5692/6160/5686/6191/5713/55110/6128/22794/6135/5682/4686/6132/6156/7316/6155/10213/5709/5694/6147/5699/6175/9978/6129/5695/6143/5710/9045/6217/5700/6181/6187/122706/5707/6124/5702/4116/8453/22916/5693/6208/65109/6157/5721/9939/5696/5719/5691/5714/6152/5690/6136/6122/6133/6210/6231/7314/5704/6233/6165/6125/5717/9861/6230/6130 104 Bovine_viral_diarrhea_virus R-HSA-2871837 FCERI mediated NF-kB activation 72/865 82/10654 1.8413667087447528e-68 3.206608597085505e-66 1.6669214416005134e-66 7322/5716/9491/5715/8454/6500/23198/1147/5718/7311/5711/5689/5170/5701/8945/23118/10892/5688/143471/5706/5687/5705/5684/23291/10197/8517/5720/5685/5683/5698/5708/5692/5686/4790/5713/6885/5682/7334/7316/10213/5709/5694/5699/3551/5695/5710/5700/10454/7321/122706/5707/5702/7335/5970/4792/5693/5721/84433/5696/997/5719/5691/8915/5714/7189/5690/7314/5704/6233/5717/257397/9861 72 Bovine_viral_diarrhea_virus R-HSA-376176 Signaling by ROBO receptors 114/865 218/10654 3.125388696046713e-67 4.762311025601179e-65 2.475636835552791e-65 5716/9491/5715/6142/23198/10921/6158/5718/7311/5711/25873/4650/5689/6154/6138/5701/6141/26986/5688/25/6202/143471/6228/5706/23521/5687/6203/5705/5684/9349/387/10197/3921/5720/6188/5685/6189/9775/6194/5683/6134/5698/5708/5692/6160/5686/6191/5713/55110/6128/22794/6135/5682/4686/6132/6156/7316/6155/10213/5709/2817/5694/6147/5699/6175/9978/6129/5695/6143/5710/9045/6217/5700/6181/6187/122706/5707/6124/5702/5567/4116/8453/22916/5693/6208/65109/6157/5721/9939/5696/5719/5691/5714/6152/5690/6136/5578/6122/6714/80728/6133/6210/6231/7314/5704/6233/6165/5568/6125/5717/9861/5566/6230/6130 114 Bovine_viral_diarrhea_virus R-HSA-5663205 Infectious disease 150/865 383/10654 5.4041726839535286e-67 7.31965166859928e-65 3.805043223087749e-65 5716/9491/5715/2962/6142/6500/23198/3839/10898/6158/7514/1025/5718/7311/5711/3303/25873/9883/5689/6154/6138/5701/8945/6141/1173/6881/5688/2963/3932/6202/143471/6228/5706/5437/3838/23521/6917/5687/6203/5705/5441/5434/5610/5440/5684/9349/8065/10197/161/999/3921/5720/6188/5685/6189/6194/7040/5683/5438/6134/7251/5698/5708/3320/5692/5431/6160/5686/6191/5713/6128/6135/5606/5435/904/79720/5682/4686/6132/6156/7316/1499/6155/1938/10213/5709/3159/5694/6147/5699/6175/9978/5433/6129/5695/6143/2547/5710/801/9045/6217/5700/6181/5439/6187/122706/5707/6124/5702/2071/5430/5901/292/5432/4233/22916/5693/6208/6157/5721/5696/4836/5436/5719/5691/5714/6152/5690/6136/6122/6714/6133/6210/6231/291/8148/7314/5704/7520/6233/6165/8106/25920/6125/5717/9861/3326/4869/6230/6130 150 Bovine_viral_diarrhea_virus R-HSA-9020702 Interleukin-1 signaling 78/865 103/10654 2.6966640168954538e-64 3.287233436595558e-62 1.7088334086011196e-62 5716/9491/5715/8454/6500/23198/51135/28512/1147/5718/7311/5711/5689/5701/8945/23118/5688/143471/5706/5687/5705/5684/351/23291/10197/8517/5720/5685/4615/5683/5698/5708/5692/5686/4790/5713/6885/5682/3656/7334/7316/10213/5709/5694/5699/9978/3551/5695/79155/5710/5700/10454/122706/5707/5702/7335/5970/4792/5693/5721/5696/5719/4793/3654/5691/4791/5714/7189/5690/3553/8878/7314/28511/5704/6233/5717/257397/9861 78 Bovine_viral_diarrhea_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 69/865 83/10654 3.9372332836988525e-62 4.363170338935364e-60 2.268147786398765e-60 5716/9491/5715/8454/6500/23198/1147/5718/7311/5711/5689/5701/8945/10892/5688/143471/5706/5687/5705/5684/23291/10197/8517/5720/5685/4794/5683/5698/5708/5692/5686/4790/5713/3845/6885/5579/5966/5682/7316/10213/5709/5694/3265/5699/3551/5695/5710/801/5700/122706/5707/5702/5970/4792/5693/5721/84433/5696/5719/4793/5691/8915/5714/5690/7314/5704/6233/5717/9861 69 Bovine_viral_diarrhea_virus R-HSA-5621481 C-type lectin receptors (CLRs) 89/865 142/10654 8.155119801470752e-62 8.284242531660705e-60 4.3064755442854324e-60 7322/5716/9491/5715/8454/6500/23198/1147/5718/7311/5711/5971/5689/5170/5701/8945/23118/10892/5688/1387/143471/5706/5687/5705/5684/23291/841/10197/8517/5720/5685/5683/5698/5708/5692/5686/4790/5713/3845/6885/2033/5682/7334/7316/10213/5709/5694/3265/5699/3551/5695/5710/801/5700/10454/7321/122706/5707/9020/5702/5567/7335/5970/4792/5693/6850/9040/5721/84433/5696/997/5719/5691/8915/4791/5714/7189/5690/3553/6714/7314/5704/6233/5568/5717/257397/9861/5580/5566 89 Bovine_viral_diarrhea_virus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 58/865 60/10654 1.4129364858627165e-61 1.3248996740512703e-59 6.887350319751866e-60 5716/9491/5715/8454/6500/23198/1147/5718/7311/5711/5971/5689/5701/8945/5688/143471/5706/5687/5705/5684/23291/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/9020/5702/5970/5693/9040/5721/5696/5719/5691/4791/5714/5690/7314/5704/6233/5717/9861 58 Bovine_viral_diarrhea_virus R-HSA-202424 Downstream TCR signaling 74/865 98/10654 7.586174154900659e-61 6.605390210588502e-59 3.4337419859024042e-59 7322/5295/5716/9491/5715/8454/6500/23198/1147/5718/7311/5711/5689/5170/5701/8945/23118/10892/5688/3932/143471/5706/5687/5705/5684/23291/10197/8517/5290/5720/5685/5683/5698/5708/5692/5686/4790/5713/6885/5682/7334/5291/7316/10213/5709/5694/5699/3551/5695/5710/5700/7321/122706/5707/5702/7335/5970/4792/5693/5721/84433/5696/997/5719/5691/8915/5714/7189/5690/7314/5704/6233/5717/9861 74 Bovine_viral_diarrhea_virus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 57/865 59/10654 1.7910653785164638e-60 1.4555391309410463e-58 7.566465669241483e-59 5716/9491/5715/8454/6500/23198/1147/5718/7311/5711/5971/5689/5701/8945/5688/143471/5706/5687/5705/5684/23291/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/9020/5702/5693/9040/5721/5696/5719/5691/4791/5714/5690/7314/5704/6233/5717/9861 57 Bovine_viral_diarrhea_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 85/865 134/10654 1.1230272373069707e-59 8.556063764232483e-58 4.4477789267026084e-58 7322/5295/5716/9491/5715/8454/6500/23198/1147/5718/7311/5711/5689/5170/3725/5701/8945/23118/10892/5688/143471/5706/5687/5705/5684/23291/10197/8517/5290/5720/5685/5683/5698/5708/5692/5686/4790/5713/3845/6885/5599/5682/7334/5291/7316/10213/5709/5694/3265/5699/3551/5695/5710/801/5700/10454/7321/122706/5707/5702/3937/7335/5970/4792/5693/6850/5721/84433/5696/997/5719/5691/8915/5714/7189/5690/5594/7314/5704/6233/5595/5717/257397/9861/4214 85 Bovine_viral_diarrhea_virus R-HSA-5610783 Degradation of GLI2 by the proteasome 57/865 60/10654 3.3136728247189393e-59 2.2440928740735484e-57 1.1665678599302934e-57 5716/9491/5715/8454/6500/23198/5718/7311/5711/5689/2932/5701/8945/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/5567/5693/5721/5696/1452/5719/5691/5714/5690/7314/5704/6233/5568/5717/9861/5566 57 Bovine_viral_diarrhea_virus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 57/865 60/10654 3.3136728247189393e-59 2.2440928740735484e-57 1.1665678599302934e-57 5716/9491/5715/8454/6500/23198/5718/7311/5711/5689/2932/5701/8945/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/5567/5693/5721/5696/1452/5719/5691/5714/5690/7314/5704/6233/5568/5717/9861/5566 57 Bovine_viral_diarrhea_virus R-HSA-72165 mRNA Splicing - Minor Pathway 51/865 52/10654 2.9225190923639172e-55 1.8750267229429555e-53 9.747127388382706e-54 2962/23451/6637/23450/2963/5437/6635/5441/6634/5434/5440/23020/6633/55599/6432/6431/5438/79622/6632/5431/24148/154007/5435/6427/10594/4686/83443/5433/6426/5439/9343/55954/5430/10907/5432/85437/22916/9416/11066/4904/5436/10081/51639/9410/57819/10992/11325/10262/6628/6636/8233 51 Bovine_viral_diarrhea_virus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 52/865 54/10654 5.7101121476863244e-55 3.480313354014815e-53 1.809203954161667e-53 5716/9491/5715/8454/6500/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/6790/5691/5714/5690/7314/5704/6233/5717/9861 52 Bovine_viral_diarrhea_virus R-HSA-5610780 Degradation of GLI1 by the proteasome 55/865 60/10654 7.75239500589849e-55 4.500080720090599e-53 2.3393191947623514e-53 5716/9491/5715/8454/6500/23198/5718/7311/5711/5689/5701/8945/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/5567/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5568/5717/9861/5566 55 Bovine_viral_diarrhea_virus R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 52/865 55/10654 9.680819833768759e-54 5.364054262438235e-52 2.7884466698223895e-52 5716/9491/5715/8454/6500/23198/5718/7311/5711/5689/5701/8945/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/991/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 52 Bovine_viral_diarrhea_virus R-HSA-446652 Interleukin-1 family signaling 82/865 140/10654 1.4285045294012325e-53 7.571074005826531e-52 3.93574245629081e-52 5716/9491/5715/8454/6500/23198/51135/28512/1147/5718/7311/5711/5689/5701/8945/23118/5688/143471/5706/5687/5705/5684/351/23291/10197/4088/8517/5720/5685/4615/5683/5698/5708/5692/5686/4790/5713/6885/5599/5682/3656/7334/7316/10213/5709/5694/5699/9978/3551/5695/79155/5710/5783/5700/10454/122706/5707/5702/7335/5970/4792/5693/5721/5696/5719/4793/3654/5691/4791/5714/29110/7189/5690/3553/8878/7314/28511/5704/6233/5717/257397/9861 82 Bovine_viral_diarrhea_virus R-HSA-180534 Vpu mediated degradation of CD4 50/865 52/10654 8.965159190090075e-53 4.371411621087921e-51 2.27243192944599e-51 5716/9491/5715/6500/23198/5718/7311/5711/5689/5701/8945/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Bovine_viral_diarrhea_virus R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 50/865 52/10654 8.965159190090075e-53 4.371411621087921e-51 2.27243192944599e-51 5716/9491/5715/23198/5718/7311/5711/5689/2932/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/595/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Bovine_viral_diarrhea_virus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 52/865 56/10654 1.2533258634486432e-52 5.876170105938062e-51 3.0546646550448714e-51 5716/9491/5715/23198/5718/7311/5711/3303/5689/5701/26986/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/3312/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/3184/5717/9861 52 Bovine_viral_diarrhea_virus R-HSA-202403 TCR signaling 75/865 119/10654 2.252602382791096e-52 1.0170082609712393e-50 5.2868094909950874e-51 7322/5295/5716/9491/5715/8454/6500/23198/1147/5718/7311/5711/5689/5170/5701/8945/23118/10892/5688/3932/143471/5706/5687/5705/5684/23291/10197/8517/5290/5720/5685/5683/5698/5708/5692/5686/4790/5713/6885/5682/7334/5291/7316/10213/5709/5694/5699/3551/5695/5710/5700/7321/122706/5707/5702/3937/7335/5970/4792/5693/5721/84433/5696/997/5719/5691/8915/5714/7189/5690/7314/5704/6233/5717/9861 75 Bovine_viral_diarrhea_virus R-HSA-9013694 Signaling by NOTCH4 62/865 82/10654 4.0993914416947295e-51 1.7397760485719603e-49 9.044041114289713e-50 5716/9491/5715/8454/6500/22938/5718/7311/5711/5689/5701/5688/1387/23385/5706/5687/5705/5684/10197/4088/5720/5685/5683/5698/5708/59/5692/5686/5713/2033/55851/51107/5682/7316/55294/10213/5709/5694/5699/9978/5695/5710/5700/5707/5702/23462/5693/5663/207/5721/5696/5719/5691/5714/5690/7314/5664/5704/83464/6233/5717/9861 62 Bovine_viral_diarrhea_virus R-HSA-6807070 PTEN Regulation 80/865 140/10654 4.1389257923369034e-51 1.7397760485719603e-49 9.044041114289713e-50 2475/10014/5716/9491/5715/23198/5718/7311/5711/1460/5689/27161/3725/5701/5688/143471/5706/5687/5705/5684/1386/10197/8841/192670/5720/5685/5683/5698/5708/8726/5692/5686/5713/23512/648/5682/57332/7316/10213/5709/5694/5699/5695/23466/1459/2444/5710/6615/5700/122706/5707/5702/2146/3065/3066/5978/7157/1107/1457/5693/10273/207/5721/5696/6045/5719/5691/5714/5690/5371/23112/5594/208/7314/5704/6233/5595/11060/5717/9861 80 Bovine_viral_diarrhea_virus R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 48/865 50/10654 1.3970061972536037e-50 5.6765018481738096e-49 2.9508692306900687e-49 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Bovine_viral_diarrhea_virus R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 49/865 52/10654 1.7952393840642899e-50 6.190002618955501e-49 3.2178071556592643e-49 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/7157/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Bovine_viral_diarrhea_virus R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 49/865 52/10654 1.7952393840642899e-50 6.190002618955501e-49 3.2178071556592643e-49 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/11200/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Bovine_viral_diarrhea_virus R-HSA-69610 p53-Independent DNA Damage Response 49/865 52/10654 1.7952393840642899e-50 6.190002618955501e-49 3.2178071556592643e-49 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/11200/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Bovine_viral_diarrhea_virus R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 49/865 52/10654 1.7952393840642899e-50 6.190002618955501e-49 3.2178071556592643e-49 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/11200/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Bovine_viral_diarrhea_virus R-HSA-180585 Vif-mediated degradation of APOBEC3G 50/865 54/10654 1.8280565568695488e-50 6.190002618955501e-49 3.2178071556592643e-49 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/8065/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Bovine_viral_diarrhea_virus R-HSA-9604323 Negative regulation of NOTCH4 signaling 50/865 54/10654 1.8280565568695488e-50 6.190002618955501e-49 3.2178071556592643e-49 5716/9491/5715/8454/6500/5718/7311/5711/5689/5701/5688/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/55294/10213/5709/5694/5699/9978/5695/5710/5700/5707/5702/5693/207/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Bovine_viral_diarrhea_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 58/865 73/10654 4.2187158735705117e-50 1.389895851319582e-48 7.225226048049639e-49 5716/9491/5715/8454/6500/23198/57154/5718/7311/5711/5689/2932/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/55294/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/11059/5693/10273/5721/5696/5719/5691/5714/5690/6772/2099/7314/5704/6233/5717/9861 58 Bovine_viral_diarrhea_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 71/865 112/10654 7.307763877690768e-50 2.344253728132907e-48 1.2186354167229482e-48 5295/5716/9491/5715/8454/6500/23198/1147/5718/7311/5711/5689/5701/8945/10892/5688/143471/5706/5687/5705/5684/23291/10197/8517/5720/5685/4794/5683/5698/5708/5692/5686/4790/5713/3845/6885/5579/5966/5682/7316/10213/5709/5694/3265/5699/3551/5695/5710/801/5700/122706/5707/5702/5970/4792/5693/6850/5721/84433/5696/5719/4793/5691/8915/5714/5690/7314/5704/6233/5717/9861 71 Bovine_viral_diarrhea_virus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 55/865 66/10654 9.54428640712253e-50 2.983201315457016e-48 1.55078553767551e-48 7322/5716/9491/5715/23198/5718/7311/5711/3091/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/7323/5682/7316/10213/5709/5694/5699/9978/112399/5695/5710/5700/7321/122706/5707/5702/8453/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 55 Bovine_viral_diarrhea_virus R-HSA-4641258 Degradation of DVL 51/865 57/10654 1.3788106047359881e-49 4.201925317932924e-48 2.1843262738185922e-48 5716/9491/5715/1857/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/8452/5713/5682/7316/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 51 Bovine_viral_diarrhea_virus R-HSA-8941858 Regulation of RUNX3 expression and activity 50/865 55/10654 1.8593053009354538e-49 5.528032102049557e-48 2.873688809147993e-48 5716/9491/5715/57154/5718/7311/5711/5689/5701/5688/5706/5687/5705/5684/10197/5720/5685/7040/5683/64750/5698/5708/5692/5686/5713/2033/5682/7316/10213/5709/5694/5699/5695/5710/5700/5707/5702/5693/5721/5696/5719/5691/5714/5690/6714/7314/5704/6233/5717/9861 50 Bovine_viral_diarrhea_virus R-HSA-8948751 Regulation of PTEN stability and activity 56/865 69/10654 2.2471564278189738e-49 6.522104013122213e-48 3.390446540218101e-48 5716/9491/5715/23198/5718/7311/5711/1460/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/1459/2444/5710/5700/122706/5707/5702/1457/5693/10273/207/5721/5696/5719/5691/5714/5690/208/7314/5704/6233/11060/5717/9861 56 Bovine_viral_diarrhea_virus R-HSA-8878166 Transcriptional regulation by RUNX2 73/865 121/10654 5.070019672525262e-49 1.4372916234437893e-47 7.471607938458282e-48 5716/9491/5715/8454/6500/23198/57154/5718/7311/5711/5689/2932/5701/5688/25/143471/5706/5687/5705/5684/10197/8841/5720/5685/10432/5683/581/5698/5708/5692/5686/5713/5682/7316/595/55294/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/11059/23462/9759/983/5693/10273/207/5721/5696/5719/5691/10413/5714/5690/6772/2099/6714/5594/208/7314/5704/6233/7525/5595/5717/9861 73 Bovine_viral_diarrhea_virus R-HSA-1234174 Cellular response to hypoxia 58/865 75/10654 7.3660513349454e-49 2.0407310402951007e-47 1.0608523692911798e-47 7322/5716/9491/5715/23198/5718/7311/5711/3091/5689/5701/5688/1387/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/55662/5692/5686/5713/2033/7323/5682/7316/10213/5709/5694/5699/9978/112399/5695/5710/5700/7321/122706/5707/5702/8453/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 58 Bovine_viral_diarrhea_virus R-HSA-5663202 Diseases of signal transduction 127/865 377/10654 8.653617617011288e-48 2.344168861141502e-46 1.2185912995183148e-46 2475/5295/10014/5716/9491/5715/8454/2962/6500/23198/4000/22938/409/56829/1147/5718/7311/5711/5689/5170/8826/2932/5701/5688/1387/2963/3932/143471/23385/5706/5437/2931/2064/5687/5705/5441/5434/5440/5684/3717/6199/1956/10197/4088/8841/5290/5720/5685/7040/5683/5438/5698/5708/3320/9444/5692/5431/5686/5713/2335/3845/2033/408/55851/5435/51107/5682/4686/5291/7316/1499/55294/10213/5709/5694/3265/5699/9978/5433/9611/5695/5710/801/5700/5439/122706/5707/5702/3065/3066/5430/5432/23462/4233/9759/9612/22916/5693/5663/207/5721/4087/5696/5436/1452/11140/5719/5691/5714/5690/5245/6772/2099/6714/5594/208/4609/7314/5664/5704/83464/6233/7415/5595/1488/5717/9861 127 Bovine_viral_diarrhea_virus R-HSA-69541 Stabilization of p53 50/865 57/10654 1.2080771095526357e-47 3.201404340314485e-46 1.6642160639603816e-46 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/11200/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/7157/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Bovine_viral_diarrhea_virus R-HSA-4641257 Degradation of AXIN 49/865 55/10654 1.8612360046048039e-47 4.827333382155864e-46 2.509438017406701e-46 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/64750/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Bovine_viral_diarrhea_virus R-HSA-169911 Regulation of Apoptosis 48/865 53/10654 2.5861597129926443e-47 6.5677681044542355e-46 3.4141845333806407e-46 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Bovine_viral_diarrhea_virus R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 49/865 56/10654 1.376670180026499e-46 3.424818264188372e-45 1.7803554207861493e-45 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/7415/5717/9861 49 Bovine_viral_diarrhea_virus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 65/865 102/10654 6.5328606236826204e-46 1.5927114200538228e-44 8.279541253593554e-45 5716/9491/5715/8454/6500/23198/7124/1147/5718/330/7311/5711/7132/5971/5689/5701/8945/5688/143471/329/5706/5687/5705/5684/23291/10197/5720/5685/5683/5698/5708/7186/5692/5686/5713/958/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/9020/5702/5693/9040/5721/5696/5719/5691/8600/4791/5714/5690/959/7314/5704/6233/5717/9861 65 Bovine_viral_diarrhea_virus R-HSA-449147 Signaling by Interleukins 138/865 461/10654 3.548085320962701e-45 8.480619620104967e-44 4.4085600892044305e-44 149233/5295/5716/9491/5715/8454/6500/23198/51135/7124/28512/1147/5718/5743/6196/7311/5711/3594/7132/3091/2939/5689/1432/3725/5701/8945/23118/5688/3932/3575/143471/5706/6888/5687/3383/5705/5684/1386/9987/351/1072/3717/23291/10197/4088/8517/598/5290/5720/3576/5685/4615/7040/5683/5698/5708/3320/5692/5686/4790/51561/5713/4843/2335/6627/6197/6885/5599/4282/5606/552900/5682/3656/7334/5291/7316/595/6195/10213/5709/5694/5699/6175/9978/3312/3551/5695/79155/5710/5783/7412/5700/3181/10454/122706/5707/7297/5702/3185/7157/7335/5970/4792/3162/3593/5693/6850/207/5721/5696/5719/4793/3654/5691/9021/4791/5714/29110/7189/5690/3553/6772/5594/9446/8878/4609/7314/28511/5704/6233/7525/5595/6624/6647/5717/257397/9861/5566 138 Bovine_viral_diarrhea_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 60/865 88/10654 4.4785748581236506e-45 1.049881298471679e-43 5.457696487025178e-44 5716/9491/5715/23198/7514/5393/5718/7311/5711/3303/5689/1432/5701/26986/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/8125/5692/5686/5713/5682/7316/10213/5709/5694/5699/3312/5695/5710/5700/122706/5707/5702/5693/207/5721/5696/5719/5691/5714/5690/5578/7314/5704/6233/3184/1994/5717/9861/5580 60 Bovine_viral_diarrhea_virus R-HSA-5658442 Regulation of RAS by GAPs 53/865 68/10654 4.912656346387229e-45 1.1299109596690626e-43 5.873722185749975e-44 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5921/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/8452/5713/3845/5682/7316/10213/5709/5694/3265/5699/9978/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 53 Bovine_viral_diarrhea_virus R-HSA-68949 Orc1 removal from chromatin 54/865 71/10654 7.521188243951654e-45 1.6978386054401974e-43 8.826033767756132e-44 5716/9491/5715/8454/6500/23198/5718/1017/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/9978/4174/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/4171/7314/5704/6233/5717/9861 54 Bovine_viral_diarrhea_virus R-HSA-69563 p53-Dependent G1 DNA Damage Response 52/865 66/10654 1.2077812367192738e-44 2.629080942072848e-43 1.3666998204981257e-43 5716/9491/5715/23198/5718/1017/7311/5711/5689/5701/5688/11200/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/57060/5694/5699/5695/5710/5700/122706/5707/5702/7157/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 52 Bovine_viral_diarrhea_virus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 52/865 66/10654 1.2077812367192738e-44 2.629080942072848e-43 1.3666998204981257e-43 5716/9491/5715/23198/5718/1017/7311/5711/5689/5701/5688/11200/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/57060/5694/5699/5695/5710/5700/122706/5707/5702/7157/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 52 Bovine_viral_diarrhea_virus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 56/865 77/10654 1.2445601147927674e-44 2.6616118946182164e-43 1.3836106908684137e-43 5716/9491/5715/23198/5718/7311/5711/5689/7277/5701/84617/5688/143471/5706/5687/5705/10383/5684/10197/5720/5685/5683/5698/5708/3320/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/7157/983/5693/5721/5696/7280/5719/5691/5714/5690/7314/5704/6233/5717/9861/3326 56 Bovine_viral_diarrhea_virus R-HSA-5387390 Hh mutants abrogate ligand secretion 49/865 59/10654 2.9475091058209474e-44 6.194851034475405e-43 3.2203275530021968e-43 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/7415/5717/9861 49 Bovine_viral_diarrhea_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 57/865 82/10654 1.3175343163167714e-43 2.7221598840510924e-42 1.4150859204686826e-42 5716/9491/5715/8454/6500/23198/5718/7311/5711/5689/2932/5701/8945/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/1499/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/3065/5693/5721/5696/1452/5719/5691/5714/5690/7314/5704/6233/1488/5717/9861 57 Bovine_viral_diarrhea_virus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 49/865 60/10654 1.4864279071305707e-43 3.019926031320276e-42 1.5698764913905326e-42 5716/9491/5715/8454/6500/5718/1017/7311/5711/5689/5701/5688/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/595/10213/5709/5694/5699/5695/5710/5700/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Bovine_viral_diarrhea_virus R-HSA-69615 G1/S DNA Damage Checkpoints 52/865 68/10654 1.9604573761671658e-43 3.9177008877832375e-42 2.036575220798333e-42 5716/9491/5715/23198/5718/1017/7311/5711/5689/5701/5688/11200/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/57060/5694/5699/5695/5710/5700/122706/5707/5702/7157/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 52 Bovine_viral_diarrhea_virus R-HSA-5687128 MAPK6/MAPK4 signaling 59/865 89/10654 3.0861017959482305e-43 6.067674337517569e-42 3.1542160970472576e-42 5716/9491/5715/23198/7514/5718/7311/5711/5689/27161/3725/5701/5688/143471/5706/5687/5705/5684/10197/192670/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/10642/122706/5707/5702/5567/983/5693/5721/5696/5719/5691/5714/5690/23112/4609/7314/5704/6233/5568/5717/9861/5566 59 Bovine_viral_diarrhea_virus R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 45/865 51/10654 3.2573065871442953e-43 6.302629729728406e-42 3.276355163677304e-42 5716/9491/5715/23198/5718/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/1728/5720/5685/5683/5698/5708/5692/5686/5713/5682/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/5704/5717/9861 45 Bovine_viral_diarrhea_virus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 56/865 80/10654 3.997064342419598e-43 7.613158489702327e-42 3.9576196285141414e-42 5716/9491/5715/8454/6500/23198/5718/1017/7311/5711/9184/5689/5701/8945/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/7321/122706/5707/991/5702/983/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 56 Bovine_viral_diarrhea_virus R-HSA-8878159 Transcriptional regulation by RUNX3 61/865 96/10654 5.1155882848749424e-43 9.593695568096239e-42 4.9871808056594586e-42 5716/9491/5715/22938/57154/5718/7311/5711/5689/5701/5688/1387/5706/5687/5705/5684/10197/4088/5720/5685/7040/5683/64750/5698/5708/5692/5686/5713/3845/2033/5682/7316/595/1499/10213/5709/5694/5699/5695/5710/5700/5707/5702/7157/9759/5693/5721/5696/5719/5691/10413/5714/5690/3676/6714/4609/7314/5704/6233/5717/9861 61 Bovine_viral_diarrhea_virus R-HSA-5678895 Defective CFTR causes cystic fibrosis 49/865 61/10654 6.985869889503193e-43 1.2902689992885442e-41 6.707326432983929e-42 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/7415/5717/9861 49 Bovine_viral_diarrhea_virus R-HSA-4608870 Asymmetric localization of PCP proteins 50/865 64/10654 1.2632206172305606e-42 2.2983073617970943e-41 1.1947506858959897e-41 5716/9491/5715/23198/57154/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/64750/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Bovine_viral_diarrhea_virus R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 48/865 59/10654 1.5748628240363364e-42 2.823173209559256e-41 1.4675966254951618e-41 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Bovine_viral_diarrhea_virus R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 44/865 50/10654 3.713126231069902e-42 6.559856341556827e-41 3.410071687420414e-41 5716/9491/5715/23198/5718/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/5704/5717/9861 44 Bovine_viral_diarrhea_virus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 57/865 86/10654 8.621502259371421e-42 1.4802269372075723e-40 7.694802609550179e-41 5716/9491/5715/8454/6500/23198/5718/1017/7311/5711/9184/5689/5701/8945/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/7321/122706/5707/991/5702/983/5693/5721/5696/5719/6790/5691/5714/5690/7314/5704/6233/5717/9861 57 Bovine_viral_diarrhea_virus R-HSA-453276 Regulation of mitotic cell cycle 57/865 86/10654 8.621502259371421e-42 1.4802269372075723e-40 7.694802609550179e-41 5716/9491/5715/8454/6500/23198/5718/1017/7311/5711/9184/5689/5701/8945/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/7321/122706/5707/991/5702/983/5693/5721/5696/5719/6790/5691/5714/5690/7314/5704/6233/5717/9861 57 Bovine_viral_diarrhea_virus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 52/865 72/10654 3.0433880272387613e-41 5.152625007227848e-40 2.678537415786162e-40 5716/9491/5715/23198/5718/7311/5711/9184/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/7321/122706/5707/991/5702/983/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 52 Bovine_viral_diarrhea_virus R-HSA-1257604 PIP3 activates AKT signaling 98/865 264/10654 5.679625150260712e-41 9.484195970092889e-40 4.930258601956667e-40 2475/5295/10014/5716/9491/5715/23198/51135/1147/5718/7311/5711/1460/5689/5170/27161/3725/2932/5701/5688/3932/143471/5706/2931/2064/5687/5705/5684/1386/6199/1956/10197/8841/5290/192670/5720/5685/4615/5683/5698/5708/8726/5692/5686/5713/23512/648/5682/5291/57332/7316/10213/5709/5694/5699/5695/23466/1459/2444/5710/6615/5700/122706/5707/5702/2146/3065/3066/5978/7157/1107/1457/4233/5693/10273/207/5721/5696/6045/5719/3654/5691/5714/7189/5690/5371/23112/2099/6714/5594/208/7314/5704/6233/5595/11060/5717/9861 98 Bovine_viral_diarrhea_virus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 50/865 67/10654 7.033736555450268e-41 1.1432166481458504e-39 5.942890394920789e-40 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/7321/122706/5707/991/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Bovine_viral_diarrhea_virus R-HSA-73856 RNA Polymerase II Transcription Termination 50/865 67/10654 7.033736555450268e-41 1.1432166481458504e-39 5.942890394920789e-40 10921/10898/29894/53981/7919/6637/199746/10250/6635/6634/10914/10569/6432/8683/6431/9775/10189/6430/51362/55110/9295/22794/81608/6427/4686/9785/7884/8189/51692/134353/11338/11051/6426/4116/1477/23283/10978/79869/22916/65109/9939/1479/51585/6429/1478/6428/55339/6628/6636/8106 50 Bovine_viral_diarrhea_virus R-HSA-5632684 Hedgehog 'on' state 56/865 85/10654 7.471289467645462e-41 1.1983555080341867e-39 6.229523905155912e-40 5716/9491/5715/23198/409/57154/5718/79577/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/64750/5698/5708/5692/5686/8452/5713/408/5682/7316/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/5693/5721/5696/1452/5719/5691/5714/5690/7314/5704/6233/5717/9861 56 Bovine_viral_diarrhea_virus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 52/865 73/10654 9.78243944573114e-41 1.5486745044605533e-39 8.050620022324192e-40 5716/9491/5715/23198/5718/7311/5711/9184/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/7321/122706/5707/991/5702/983/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 52 Bovine_viral_diarrhea_virus R-HSA-5358346 Hedgehog ligand biogenesis 49/865 65/10654 1.8986939111554585e-40 2.9673177919211586e-39 1.5425286565662433e-39 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/7415/5717/9861 49 Bovine_viral_diarrhea_virus R-HSA-9006925 Intracellular signaling by second messengers 105/865 305/10654 2.1649597341339892e-40 3.340615083429535e-39 1.736583291070835e-39 2475/5295/10014/5716/9491/5715/23198/51135/1147/5718/7311/5711/1460/5689/5170/27161/3725/2932/5701/5688/3932/143471/5706/3838/2931/2064/5687/5705/5684/1386/6199/1956/10197/8841/5290/192670/5720/5685/4615/5683/5698/5708/8726/5692/5686/5713/23512/648/5682/5291/57332/7316/10213/5709/5694/5699/5695/23466/1459/2444/5710/801/6615/5700/122706/5707/5702/5567/2146/3065/3066/5978/7157/1107/1457/4233/5693/10273/207/5721/5696/6045/5719/3654/5691/5714/7189/5690/5371/23112/5578/2099/6714/5594/208/7314/5704/6233/5568/5595/11060/5717/9861/5580/5566 105 Bovine_viral_diarrhea_virus R-HSA-68867 Assembly of the pre-replicative complex 50/865 68/10654 2.456763107008757e-40 3.743492784304594e-39 1.9460149873937792e-39 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/4174/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/4171/7314/5704/6233/5717/9861 50 Bovine_viral_diarrhea_virus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 51/865 72/10654 9.065105646763539e-40 1.3637837134236745e-38 7.089484870955938e-39 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/7321/122706/5707/991/5702/5693/5721/5696/5719/6790/5691/5714/5690/7314/5704/6233/5717/9861 51 Bovine_viral_diarrhea_virus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 52/865 75/10654 9.173934741652282e-40 1.3637837134236745e-38 7.089484870955938e-39 5716/9491/5715/23198/5718/7311/5711/9184/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/7321/122706/5707/991/5702/983/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 52 Bovine_viral_diarrhea_virus R-HSA-4086400 PCP/CE pathway 57/865 92/10654 2.371054202678209e-39 3.482307316945466e-38 1.8102404946255954e-38 5716/9491/5715/1857/23198/409/57154/5718/7311/5711/5689/5701/1173/5688/143471/5706/5687/5705/5684/387/10197/161/5720/5685/5683/64750/5698/5708/5692/5686/5713/5579/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/5578/7314/5704/6233/5717/9861 57 Bovine_viral_diarrhea_virus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 52/865 76/10654 2.6861962621217906e-39 3.898182432769599e-38 2.026428759144509e-38 5716/9491/5715/23198/5718/7311/5711/9184/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/7321/122706/5707/991/5702/983/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 52 Bovine_viral_diarrhea_virus R-HSA-162906 HIV Infection 90/865 233/10654 2.861450708003812e-39 4.1036569565372315e-38 2.1332425092486624e-38 5716/9491/5715/2962/6500/23198/7514/1025/5718/7311/5711/9883/5689/5701/8945/1173/6881/5688/2963/3932/143471/5706/5437/6917/5687/5705/5441/5434/5440/5684/8065/10197/161/5720/5685/5683/5438/7251/5698/5708/5692/5431/5686/5713/5435/904/79720/5682/4686/7316/10213/5709/3159/5694/5699/9978/5433/5695/2547/5710/5700/5439/122706/5707/5702/2071/5430/5901/292/5432/22916/5693/5721/5696/4836/5436/5719/5691/5714/5690/291/8148/7314/5704/7520/6233/25920/5717/9861/4869 90 Bovine_viral_diarrhea_virus R-HSA-69202 Cyclin E associated events during G1/S transition 54/865 83/10654 5.491284785655933e-39 7.783576922923933e-38 4.0462098420622666e-38 5716/9491/5715/8454/6500/5718/1017/7311/5711/5689/5701/5688/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/595/10213/5709/5694/5699/7027/5695/7465/5710/5700/5707/5702/5693/207/5721/5696/5719/5691/5714/5690/208/4609/7314/5704/6233/5717/9861 54 Bovine_viral_diarrhea_virus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 50/865 72/10654 2.5247468161785436e-38 3.537547550484649e-37 1.8389565436654368e-37 5716/9491/5715/23198/5718/1017/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/7321/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Bovine_viral_diarrhea_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 54/865 85/10654 3.6051818110505705e-38 4.993996167807552e-37 2.5960758974311527e-37 5716/9491/5715/8454/6500/5718/1017/7311/5711/5689/5701/5688/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/595/10213/5709/5694/5699/7027/5695/7465/5710/5700/5707/5702/5693/207/5721/5696/5719/5691/5714/5690/208/4609/7314/5704/6233/5717/9861 54 Bovine_viral_diarrhea_virus R-HSA-1236974 ER-Phagosome pathway 53/865 83/10654 1.1910557698778453e-37 1.6313449252596554e-36 8.480373429526468e-37 5716/9491/5715/23198/1147/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/8517/5720/5685/4615/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/3551/5695/5710/5700/3107/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 53 Bovine_viral_diarrhea_virus R-HSA-351202 Metabolism of polyamines 45/865 59/10654 1.281890590038224e-37 1.7362495880628834e-36 9.025709183660948e-37 5716/9491/5715/23198/5718/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/1728/5720/5685/5683/5698/5708/5692/5686/5713/5682/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/5704/5717/9861 45 Bovine_viral_diarrhea_virus R-HSA-69052 Switching of origins to a post-replicative state 55/865 90/10654 1.5425083346846125e-37 2.0662831428357612e-36 1.0741353585658033e-36 5716/9491/5715/8454/6500/23198/5718/1017/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/9978/4174/5695/5710/5700/7321/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/4171/7314/5704/6233/5717/9861 55 Bovine_viral_diarrhea_virus R-HSA-5610787 Hedgehog 'off' state 61/865 113/10654 3.924979902112057e-37 5.2005983702984756e-36 2.7034758593494955e-36 5716/9491/5715/8454/6500/23198/5718/7311/5711/5689/7277/2932/5701/8945/84617/5688/143471/5706/5687/5705/10383/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/5567/5693/5721/5696/1452/7280/5719/5691/5714/5690/7314/5704/6233/5568/5717/9861/5566 61 Bovine_viral_diarrhea_virus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 46/865 63/10654 5.965543285026041e-37 7.819351897254564e-36 4.0648070827228935e-36 5716/9491/5715/5718/7311/5711/5689/5701/5688/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/7321/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 46 Bovine_viral_diarrhea_virus R-HSA-168254 Influenza Infection 71/865 155/10654 6.458298495619475e-37 8.375176453361851e-36 4.3537465782339576e-36 2962/6142/3839/10898/6158/7514/7311/3303/25873/9883/6154/6138/6141/2963/6202/6228/5437/3838/23521/6203/5441/5434/5610/5440/9349/3921/6188/6189/6194/7040/5438/6134/3320/5431/6160/6191/6128/6135/5435/6132/6156/6155/6147/6175/5433/6129/6143/9045/6217/6181/5439/6187/6124/5430/5901/5432/6208/6157/5436/6152/6136/6122/6133/6210/6231/6233/6165/8106/6125/6230/6130 71 Bovine_viral_diarrhea_virus R-HSA-162909 Host Interactions of HIV factors 64/865 129/10654 5.490695991323182e-36 7.045429908866272e-35 3.662491952106987e-35 5716/9491/5715/6500/23198/7514/1025/5718/7311/5711/9883/5689/5701/8945/1173/5688/3932/143471/5706/5687/5705/5684/8065/10197/161/5720/5685/5683/5698/5708/5692/5686/5713/904/5682/7316/10213/5709/3159/5694/5699/9978/5695/5710/5700/122706/5707/5702/5901/292/5693/5721/5696/5719/5691/5714/5690/291/7314/5704/6233/5717/9861/4869 64 Bovine_viral_diarrhea_virus R-HSA-5357801 Programmed Cell Death 75/865 181/10654 2.875229574499872e-35 3.650942553453483e-34 1.8979037322904857e-34 5716/9491/5715/23198/4000/5718/330/7311/5711/5689/11035/5701/5688/143471/329/5706/5687/5705/5684/841/10197/999/598/5720/5685/5683/581/5698/5708/7186/5692/5686/708/5713/22985/5599/5682/7316/1499/10213/5709/5694/5699/4137/7531/7027/5695/5710/5700/122706/5707/8655/5702/8737/7157/5693/207/5721/10971/140735/5696/4836/5719/5691/5714/5690/5594/208/7314/5704/6233/5595/5717/9861/5580 75 Bovine_viral_diarrhea_virus R-HSA-5358351 Signaling by Hedgehog 68/865 149/10654 2.932505153453995e-35 3.6852822495468243e-34 1.9157548587946883e-34 5716/9491/5715/8454/6500/23198/409/57154/5718/79577/7311/5711/5689/7277/2932/5701/8945/84617/5688/143471/5706/5687/5705/10383/5684/10197/5720/5685/5683/64750/5698/5708/5692/5686/8452/5713/408/5682/7316/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/5567/5693/5721/5696/1452/7280/5719/5691/5714/5690/7314/5704/6233/5568/7415/5717/9861/5566 68 Bovine_viral_diarrhea_virus R-HSA-72187 mRNA 3'-end processing 43/865 58/10654 4.415827385436858e-35 5.492748553926051e-34 2.8553470311847356e-34 10921/10898/29894/53981/7919/199746/10250/10914/10569/6432/8683/6431/9775/10189/6430/51362/55110/9295/22794/81608/6427/4686/9785/8189/51692/11338/11051/6426/4116/1477/23283/10978/79869/22916/65109/9939/1479/51585/6429/1478/6428/55339/8106 43 Bovine_viral_diarrhea_virus R-HSA-5619084 ABC transporter disorders 49/865 77/10654 8.941237149412673e-35 1.1009462712256614e-33 5.723152327428421e-34 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/7415/5717/9861 49 Bovine_viral_diarrhea_virus R-HSA-69242 S Phase 70/865 161/10654 1.370308305823147e-34 1.670405824798416e-33 8.683427369531943e-34 5716/9491/5715/8454/6500/23198/5718/1017/7311/5711/5689/2932/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5983/5692/5985/5686/5713/5885/5682/8243/9126/7316/595/10213/5709/5981/5694/5699/9978/4174/7027/5695/7465/5710/5700/7321/122706/5707/5702/5424/5693/207/5721/5696/5719/5691/5714/5690/5111/4171/208/4609/7314/5704/6233/5717/9861 70 Bovine_viral_diarrhea_virus R-HSA-157118 Signaling by NOTCH 85/865 235/10654 1.426544547041717e-34 1.7217403988552998e-33 8.950284703690607e-34 10014/5716/9491/5715/8454/6500/22938/409/5718/7311/5711/3091/5689/27161/3725/5701/5688/1387/23385/5706/5687/5705/5684/1956/10197/4088/8841/192670/5720/5685/5683/5698/5708/59/5692/5686/5713/2033/408/55851/51107/5682/7316/595/55294/10213/5709/5694/5699/9978/4854/9611/7027/5695/5710/5700/5707/5702/3065/3066/7157/23462/9759/9612/5693/5663/207/5721/4904/5696/5719/5691/5714/5690/23112/6772/4609/7314/5664/5704/83464/6233/11060/5717/9861 85 Bovine_viral_diarrhea_virus R-HSA-69002 DNA Replication Pre-Initiation 51/865 85/10654 2.604037130779342e-34 3.1120796690392333e-33 1.6177815817638433e-33 5716/9491/5715/23198/5718/1017/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/4174/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/4171/7314/5704/6233/5717/9861 51 Bovine_viral_diarrhea_virus R-HSA-69239 Synthesis of DNA 60/865 119/10654 2.6428122294845607e-34 3.127755444409398e-33 1.625930467194385e-33 5716/9491/5715/8454/6500/23198/5718/1017/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5983/5692/5985/5686/5713/5682/7316/10213/5709/5981/5694/5699/9978/4174/5695/5710/5700/7321/122706/5707/5702/5424/5693/5721/5696/5719/5691/5714/5690/5111/4171/7314/5704/6233/5717/9861 60 Bovine_viral_diarrhea_virus R-HSA-2262752 Cellular responses to stress 125/865 479/10654 4.5159071514923195e-34 5.293164247758786e-33 2.7515952481764946e-33 2475/7322/5716/9491/5715/23198/2882/7295/5718/1017/6196/7311/5711/3303/7014/3091/9883/5689/1432/7277/3725/2932/5701/84617/5688/1387/143471/25913/5706/5687/5705/10383/5684/23411/10197/192670/5720/529/3576/5685/2876/5683/3309/5698/5708/3320/8726/55662/5692/5686/4790/5713/2877/6197/7001/5599/2033/847/23512/648/7323/5606/5682/1781/57332/7316/6195/10213/5709/3159/5694/5699/9978/3312/112399/7531/7027/5695/23466/1915/1783/5710/5700/7321/122706/5707/8655/5702/2146/493869/7157/8453/5970/5693/1639/10641/5721/257202/140735/5696/2878/7280/6045/10963/5719/6667/5691/5714/5690/23112/2936/5594/10728/2880/7314/5704/6233/7415/5595/2950/1778/6647/5717/9861/3326 125 Bovine_viral_diarrhea_virus R-HSA-109581 Apoptosis 73/865 178/10654 5.5089408597273755e-34 6.395618007626353e-33 3.324694132888101e-33 5716/9491/5715/23198/4000/5718/7311/5711/5689/5701/5688/143471/329/5706/5687/5705/5684/841/10197/999/598/5720/5685/5683/581/5698/5708/7186/5692/5686/708/5713/22985/5599/5682/7316/1499/10213/5709/5694/5699/4137/7531/7027/5695/5710/5700/122706/5707/8655/5702/8737/7157/5693/207/5721/10971/140735/5696/4836/5719/5691/5714/5690/5594/208/7314/5704/6233/5595/5717/9861/5580 73 Bovine_viral_diarrhea_virus R-HSA-168255 Influenza Life Cycle 65/865 144/10654 2.223767256379834e-33 2.557332344836809e-32 1.329402073823893e-32 2962/6142/6158/7514/7311/3303/25873/9883/6154/6138/6141/2963/6202/6228/5437/23521/6203/5441/5434/5440/9349/3921/6188/6189/6194/5438/6134/3320/5431/6160/6191/6128/6135/5435/6132/6156/6155/6147/6175/5433/6129/6143/9045/6217/6181/5439/6187/6124/5430/5901/5432/6208/6157/5436/6152/6136/6122/6133/6210/6231/6233/6165/6125/6230/6130 65 Bovine_viral_diarrhea_virus R-HSA-3858494 Beta-catenin independent WNT signaling 65/865 146/10654 6.218311984120853e-33 7.084226456676e-32 3.6826599256672446e-32 5716/9491/5715/1857/23198/409/57154/5718/7311/5711/5689/27161/5701/1173/5688/143471/5706/5687/5705/5684/387/10197/161/192670/5720/5685/5683/64750/5698/5708/5692/5686/5713/3845/6885/5579/5682/7316/1499/10213/5709/5694/5699/5695/5710/801/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/23112/5578/7314/5704/6233/2787/5717/9861 65 Bovine_viral_diarrhea_virus R-HSA-8953897 Cellular responses to external stimuli 125/865 493/10654 1.0143541914134e-32 1.14490533271568e-31 5.951668842406109e-32 2475/7322/5716/9491/5715/23198/2882/7295/5718/1017/6196/7311/5711/3303/7014/3091/9883/5689/1432/7277/3725/2932/5701/84617/5688/1387/143471/25913/5706/5687/5705/10383/5684/23411/10197/192670/5720/529/3576/5685/2876/5683/3309/5698/5708/3320/8726/55662/5692/5686/4790/5713/2877/6197/7001/5599/2033/847/23512/648/7323/5606/5682/1781/57332/7316/6195/10213/5709/3159/5694/5699/9978/3312/112399/7531/7027/5695/23466/1915/1783/5710/5700/7321/122706/5707/8655/5702/2146/493869/7157/8453/5970/5693/1639/10641/5721/257202/140735/5696/2878/7280/6045/10963/5719/6667/5691/5714/5690/23112/2936/5594/10728/2880/7314/5704/6233/7415/5595/2950/1778/6647/5717/9861/3326 125 Bovine_viral_diarrhea_virus R-HSA-168273 Influenza Viral RNA Transcription and Replication 62/865 134/10654 1.1949032577051058e-32 1.3363184138922238e-31 6.946709426735623e-32 2962/6142/6158/7311/25873/9883/6154/6138/6141/2963/6202/6228/5437/23521/6203/5441/5434/5440/9349/3921/6188/6189/6194/5438/6134/3320/5431/6160/6191/6128/6135/5435/6132/6156/6155/6147/6175/5433/6129/6143/9045/6217/6181/5439/6187/6124/5430/5432/6208/6157/5436/6152/6136/6122/6133/6210/6231/6233/6165/6125/6230/6130 62 Bovine_viral_diarrhea_virus R-HSA-69275 G2/M Transition 75/865 196/10654 1.7854608360006008e-32 1.9786152355315747e-31 1.0285621275333604e-31 5716/9491/5715/8454/6500/23198/7514/5718/1017/7311/5711/5689/7277/5701/8945/84617/5688/143471/5706/5687/5705/10383/5684/23291/10197/5720/5685/5683/5698/5708/3320/5692/5686/5713/2033/5682/1781/7316/10213/5709/5694/10426/5699/9978/7531/5695/7465/5710/5700/122706/5707/8655/5702/203068/7157/983/5693/1639/5721/5696/7280/5719/6790/5691/5714/5690/1063/7314/5704/6233/1778/5717/9861/3326/5566 75 Bovine_viral_diarrhea_virus R-HSA-69306 DNA Replication 60/865 127/10654 2.9091750466919245e-32 3.19485079452023e-31 1.6608092727439912e-31 5716/9491/5715/8454/6500/23198/5718/1017/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5983/5692/5985/5686/5713/5682/7316/10213/5709/5981/5694/5699/9978/4174/5695/5710/5700/7321/122706/5707/5702/5424/5693/5721/5696/5719/5691/5714/5690/5111/4171/7314/5704/6233/5717/9861 60 Bovine_viral_diarrhea_virus R-HSA-1236975 Antigen processing-Cross presentation 53/865 99/10654 3.8771770039554596e-32 4.219891756983665e-31 2.1936659364484844e-31 5716/9491/5715/23198/1147/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/8517/5720/5685/4615/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/3551/5695/5710/5700/3107/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 53 Bovine_viral_diarrhea_virus R-HSA-453274 Mitotic G2-G2/M phases 75/865 198/10654 3.976223725420339e-32 4.289395328572915e-31 2.2297966303707915e-31 5716/9491/5715/8454/6500/23198/7514/5718/1017/7311/5711/5689/7277/5701/8945/84617/5688/143471/5706/5687/5705/10383/5684/23291/10197/5720/5685/5683/5698/5708/3320/5692/5686/5713/2033/5682/1781/7316/10213/5709/5694/10426/5699/9978/7531/5695/7465/5710/5700/122706/5707/8655/5702/203068/7157/983/5693/1639/5721/5696/7280/5719/6790/5691/5714/5690/1063/7314/5704/6233/1778/5717/9861/3326/5566 75 Bovine_viral_diarrhea_virus R-HSA-927802 Nonsense-Mediated Decay (NMD) 57/865 115/10654 4.063131398968436e-32 4.306919282906542e-31 2.2389062720173903e-31 6142/10921/6158/7311/25873/6154/6138/6141/26986/6202/6228/23521/6203/9349/3921/6188/6189/9775/6194/6134/6160/6191/55110/6128/22794/6135/4686/6132/6156/6155/6147/6175/6129/6143/5976/9045/6217/6181/6187/6124/4116/22916/6208/65109/6157/9939/6152/6136/6122/6133/6210/6231/6233/6165/6125/6230/6130 57 Bovine_viral_diarrhea_virus R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 57/865 115/10654 4.063131398968436e-32 4.306919282906542e-31 2.2389062720173903e-31 6142/10921/6158/7311/25873/6154/6138/6141/26986/6202/6228/23521/6203/9349/3921/6188/6189/9775/6194/6134/6160/6191/55110/6128/22794/6135/4686/6132/6156/6155/6147/6175/6129/6143/5976/9045/6217/6181/6187/6124/4116/22916/6208/65109/6157/9939/6152/6136/6122/6133/6210/6231/6233/6165/6125/6230/6130 57 Bovine_viral_diarrhea_virus R-HSA-8951664 Neddylation 81/865 234/10654 2.116256659855397e-31 2.2238938520376974e-30 1.1560676127340736e-30 7322/5716/9491/5715/8454/9318/6500/23198/5718/25793/7311/5711/3091/5689/5701/8945/5688/83987/143471/5706/5687/26270/5705/55827/26259/5684/23291/8065/10197/5720/8533/5685/5683/55832/80204/5698/5708/5692/5686/8452/23363/5713/8450/7323/5682/7316/55294/10213/5709/5694/5699/9978/5695/5710/5700/7321/122706/5707/10987/5702/8453/5693/9040/5721/5696/51676/5719/5691/4738/9021/150684/5714/5690/9817/9820/7314/5704/6233/5717/2873/9861 81 Bovine_viral_diarrhea_virus R-HSA-5688426 Deubiquitination 92/865 297/10654 2.7824113855657783e-31 2.898939725645029e-30 1.5069830446339171e-30 5716/9491/5715/672/23198/409/5718/330/7128/7311/5711/3091/5689/84282/5701/6881/5688/143471/329/5706/5687/5705/5684/4287/387/10197/4088/7706/8517/5720/5685/7040/5683/8607/64750/5698/5708/580/7186/5692/5686/5713/6885/2033/408/5682/64135/7316/10213/5709/1540/5694/5699/5695/79155/5710/5700/10454/7321/122706/5707/991/5702/8737/7157/4792/983/5693/8237/154/5721/4087/5696/5719/5691/4738/5714/7189/5690/55611/9817/2099/57506/9100/4609/7314/5704/6233/7415/5717/9861/23586 92 Bovine_viral_diarrhea_virus R-HSA-69206 G1/S Transition 59/865 131/10654 2.5882763704062888e-30 2.6738210979027677e-29 1.3899575155973113e-29 5716/9491/5715/8454/6500/5718/1017/7311/5711/5689/5701/5688/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/595/10213/5709/5694/5699/4174/7027/5695/7465/5710/5700/5707/5702/3065/983/5693/207/5721/5696/5719/5691/5714/5690/5111/4171/208/4609/7314/5704/6233/5717/9861 59 Bovine_viral_diarrhea_virus R-HSA-5689603 UCH proteinases 52/865 102/10654 3.6390659789279655e-30 3.727749099422848e-29 1.9378307999244893e-029 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/7040/5683/8607/5698/5708/580/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/4738/5714/5690/7314/5704/6233/5717/9861 52 Bovine_viral_diarrhea_virus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 50/865 95/10654 6.578908842286363e-30 6.683074898955897e-29 3.4741255465406936e-29 6142/6158/7311/25873/6154/6138/6141/26986/6202/6228/23521/6203/9349/3921/6188/6189/6194/6134/6160/6191/6128/6135/4686/6132/6156/6155/6147/6175/6129/6143/5976/9045/6217/6181/6187/6124/22916/6208/6157/6152/6136/6122/6133/6210/6231/6233/6165/6125/6230/6130 50 Bovine_viral_diarrhea_virus R-HSA-5689880 Ub-specific processing proteases 76/865 220/10654 1.9624341184872425e-29 1.9770307358974781e-28 1.0277384422177645e-28 5716/9491/5715/23198/409/5718/330/7311/5711/3091/5689/5701/6881/5688/143471/329/5706/5687/5705/5684/10197/4088/8517/5720/5685/5683/8607/64750/5698/5708/7186/5692/5686/5713/6885/408/5682/64135/7316/10213/5709/1540/5694/5699/5695/5710/5700/10454/122706/5707/991/5702/8737/7157/4792/5693/8237/154/5721/4087/5696/5719/5691/5714/7189/5690/55611/9817/9100/4609/7314/5704/6233/5717/9861/23586 76 Bovine_viral_diarrhea_virus R-HSA-453279 Mitotic G1-G1/S phases 62/865 149/10654 2.059542536158035e-29 2.057854386538233e-28 1.0697537590743204e-28 5716/9491/5715/8454/6500/5718/1017/7311/5711/5689/5701/5688/25/5706/5687/5705/5684/3717/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/595/10213/5709/5694/5699/4174/7027/5695/7465/5710/5700/5707/5702/3065/983/5693/207/5721/5696/5719/5691/5714/5690/5111/6714/4171/208/4609/7314/5704/6233/5717/9861 62 Bovine_viral_diarrhea_virus R-HSA-156902 Peptide chain elongation 48/865 89/10654 2.117759384027617e-29 2.0988200724631425e-28 1.0910493360587297e-28 6142/6158/7311/25873/6154/6138/6141/6202/6228/23521/6203/9349/3921/6188/6189/6194/6134/6160/6191/6128/6135/6132/6156/6155/1938/6147/6175/6129/6143/1915/9045/6217/6181/6187/6124/6208/6157/6152/6136/6122/6133/6210/6231/6233/6165/6125/6230/6130 48 Bovine_viral_diarrhea_virus R-HSA-156842 Eukaryotic Translation Elongation 49/865 93/10654 2.324483568025334e-29 2.2851173140507116e-28 1.187893979585103e-28 6142/6158/7311/25873/6154/6138/6141/6202/6228/23521/6203/9349/3921/6188/6189/6194/6134/6160/6191/6128/6135/6132/6156/6155/1938/6147/6175/6129/6143/1915/9045/6217/6181/6187/6124/1936/6208/6157/6152/6136/6122/6133/6210/6231/6233/6165/6125/6230/6130 49 Bovine_viral_diarrhea_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 49/865 94/10654 4.488524658284108e-29 4.377209246758662e-28 2.2754457636101334e-28 7322/8454/6500/28512/1147/330/6196/7311/1432/3725/11035/8945/23118/329/1386/351/23291/841/8517/9641/4790/6197/6885/5599/7323/5606/3656/7334/7316/6195/3551/79155/10454/7321/8737/7335/5970/4792/4793/3654/4791/29110/7189/5594/7314/28511/6233/5595/257397 49 Bovine_viral_diarrhea_virus R-HSA-382556 ABC-family proteins mediated transport 51/865 103/10654 8.157482561582844e-29 7.892040668705942e-28 4.102593568983185e-28 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/8894/5683/5698/1965/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/7415/5717/9861 51 Bovine_viral_diarrhea_virus R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 52/865 111/10654 7.220770441383238e-28 6.930802494524542e-27 3.602904107511571e-27 6142/6158/7311/25873/6154/3646/6138/6141/26986/6202/6228/23521/6203/9349/3921/6188/6189/6194/8894/6134/1965/6160/27335/6191/6128/6135/6132/6156/6155/6147/6175/6129/6143/9045/6217/6181/6187/6124/6208/6157/6152/6136/6122/6133/6210/6231/8668/6233/6165/6125/6230/6130 52 Bovine_viral_diarrhea_virus R-HSA-166166 MyD88-independent TLR4 cascade 49/865 99/10654 1.0227005660068449e-27 9.664123953196465e-27 5.0237922540687125e-27 7322/8454/6500/28512/1147/330/6196/7311/1432/3725/11035/8945/23118/329/1386/351/23291/841/8517/9641/4790/6197/6885/5599/7323/5606/3656/7334/7316/6195/3551/79155/10454/7321/8737/7335/5970/4792/4793/3654/4791/29110/7189/5594/7314/28511/6233/5595/257397 49 Bovine_viral_diarrhea_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 49/865 99/10654 1.0227005660068449e-27 9.664123953196465e-27 5.0237922540687125e-27 7322/8454/6500/28512/1147/330/6196/7311/1432/3725/11035/8945/23118/329/1386/351/23291/841/8517/9641/4790/6197/6885/5599/7323/5606/3656/7334/7316/6195/3551/79155/10454/7321/8737/7335/5970/4792/4793/3654/4791/29110/7189/5594/7314/28511/6233/5595/257397 49 Bovine_viral_diarrhea_virus R-HSA-69481 G2/M Checkpoints 64/865 168/10654 1.0709848246926897e-27 1.0042542317695297e-26 5.220509024008092e-27 5716/9491/5715/672/23198/5718/1017/7311/5711/5689/7341/5701/5688/11200/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/580/5983/5692/5985/5686/5713/5682/7334/7316/10213/5709/5694/5699/4174/7531/5695/7465/5710/5700/122706/5707/5702/7157/983/5693/5721/10971/5696/5719/5691/5714/5690/8924/4171/7314/5704/6233/5717/9861 64 Bovine_viral_diarrhea_virus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 89/865 309/10654 1.1588727774912247e-27 1.078370928062445e-26 5.605796802327982e-27 7322/5716/9491/5715/8454/9354/6500/23198/57154/5718/25793/7311/5711/5689/6047/5701/8945/5688/143471/5706/5687/26270/5705/26259/5684/23291/8065/10197/5720/5685/5683/64750/80204/5698/5708/9690/27246/5692/5686/8452/5713/57531/7323/5682/7334/5930/7316/55294/10213/5709/5694/5699/9978/51320/5695/7319/5710/5700/7321/122706/5707/991/5702/7332/8453/7335/11059/5693/9040/10273/5721/5696/997/51676/5719/10075/5691/9246/9021/5714/5690/8924/9817/9820/7314/5704/6233/5717/9861 89 Bovine_viral_diarrhea_virus R-HSA-72689 Formation of a pool of free 40S subunits 49/865 101/10654 3.3280892032741805e-27 3.0734399536297163e-26 1.597695135862087e-26 6142/6158/7311/25873/6154/3646/6138/6141/6202/6228/23521/6203/9349/3921/6188/6189/6194/6134/6160/27335/6191/6128/6135/6132/6156/6155/6147/6175/6129/6143/9045/6217/6181/6187/6124/6208/6157/6152/6136/6122/6133/6210/6231/8668/6233/6165/6125/6230/6130 49 Bovine_viral_diarrhea_virus R-HSA-192823 Viral mRNA Translation 46/865 89/10654 3.7791116824009786e-27 3.4637121359750324e-26 1.8005739871827376e-26 6142/6158/7311/25873/6154/6138/6141/6202/6228/23521/6203/9349/3921/6188/6189/6194/6134/6160/6191/6128/6135/6132/6156/6155/6147/6175/6129/6143/9045/6217/6181/6187/6124/6208/6157/6152/6136/6122/6133/6210/6231/6233/6165/6125/6230/6130 46 Bovine_viral_diarrhea_virus R-HSA-72613 Eukaryotic Translation Initiation 53/865 119/10654 4.876902145144377e-27 4.403662011059997e-26 2.2891969523406748e-26 6142/6158/7311/25873/6154/3646/6138/6141/26986/6202/6228/23521/6203/9349/3921/6188/6189/6194/8894/6134/1965/6160/27335/6191/6128/6135/6132/6156/6155/6147/6175/6129/6143/9045/6217/6181/6187/6124/6208/6157/8892/6152/6136/6122/6133/6210/6231/8668/6233/6165/6125/6230/6130 53 Bovine_viral_diarrhea_virus R-HSA-72737 Cap-dependent Translation Initiation 53/865 119/10654 4.876902145144377e-27 4.403662011059997e-26 2.2891969523406748e-26 6142/6158/7311/25873/6154/3646/6138/6141/26986/6202/6228/23521/6203/9349/3921/6188/6189/6194/8894/6134/1965/6160/27335/6191/6128/6135/6132/6156/6155/6147/6175/6129/6143/9045/6217/6181/6187/6124/6208/6157/8892/6152/6136/6122/6133/6210/6231/8668/6233/6165/6125/6230/6130 53 Bovine_viral_diarrhea_virus R-HSA-75067 Processing of Capped Intronless Pre-mRNA 26/865 28/10654 1.0101010714702553e-26 9.053773574428244e-26 4.706508088429519e-26 10898/29894/53981/6637/6635/6634/10914/81608/4686/7884/8189/51692/134353/11051/1477/23283/10978/79869/22916/1479/51585/1478/55339/6628/6636/8106 26 Bovine_viral_diarrhea_virus R-HSA-2467813 Separation of Sister Chromatids 67/865 190/10654 1.2168330929297637e-26 1.0827149929061182e-25 5.628378962302865e-26 5716/9491/5715/23198/7514/5718/7311/5711/9184/5689/7277/5701/84617/5688/143471/5706/5687/5705/10383/5684/10197/5720/5685/54908/5683/5698/5708/5692/5686/5713/5885/5682/8243/1781/9126/7316/10213/5709/5694/5699/5695/5501/1783/5710/5700/7321/122706/5707/8655/991/5702/5693/5721/140735/5696/7280/5719/5691/5714/5690/1063/7314/5704/6233/1778/5717/9861 67 Bovine_viral_diarrhea_virus R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 51/865 112/10654 1.2745770808957749e-26 1.1258764214579345e-25 5.852749067118662e-26 6142/6158/7311/25873/6154/3646/6138/6141/6202/6228/23521/6203/9349/3921/6188/6189/6194/8894/6134/1965/6160/27335/6191/6128/6135/6132/6156/6155/6147/6175/6129/6143/9045/6217/6181/6187/6124/6208/6157/6152/6136/6122/6133/6210/6231/8668/6233/6165/6125/6230/6130 51 Bovine_viral_diarrhea_virus R-HSA-68882 Mitotic Anaphase 69/865 201/10654 1.3235960420873287e-26 1.160765162089535e-25 6.034114481912699e-26 5716/9491/5715/23198/4000/7514/5718/7311/5711/9184/5689/7277/5701/84617/5688/143471/5706/5687/5705/10383/5684/10197/5720/5685/54908/5683/5698/5708/5692/5686/5713/5885/5682/8243/1781/9126/7316/10213/5709/5694/5699/5695/5501/1783/5710/5700/7321/122706/5707/8655/991/5702/7112/5693/5721/140735/5696/7280/5719/5691/5714/5690/1063/7314/5704/6233/1778/5717/9861 69 Bovine_viral_diarrhea_virus R-HSA-2555396 Mitotic Metaphase and Anaphase 69/865 202/10654 1.8597967593049848e-26 1.6193516068519831e-25 8.418027436854144e-26 5716/9491/5715/23198/4000/7514/5718/7311/5711/9184/5689/7277/5701/84617/5688/143471/5706/5687/5705/10383/5684/10197/5720/5685/54908/5683/5698/5708/5692/5686/5713/5885/5682/8243/1781/9126/7316/10213/5709/5694/5699/5695/5501/1783/5710/5700/7321/122706/5707/8655/991/5702/7112/5693/5721/140735/5696/7280/5719/5691/5714/5690/1063/7314/5704/6233/1778/5717/9861 69 Bovine_viral_diarrhea_virus R-HSA-2408557 Selenocysteine synthesis 46/865 93/10654 4.5144273978332765e-26 3.8754133788442004e-25 2.014592508150951e-25 6142/6158/7311/25873/6154/6138/6141/6202/6228/23521/6203/9349/3921/6188/6189/6194/6134/6160/6191/6128/6135/6132/6156/6155/6147/6175/6129/6143/9045/6217/6181/6187/6124/6208/6157/6152/6136/6122/6133/6210/6231/6233/6165/6125/6230/6130 46 Bovine_viral_diarrhea_virus R-HSA-72764 Eukaryotic Translation Termination 46/865 93/10654 4.5144273978332765e-26 3.8754133788442004e-25 2.014592508150951e-25 6142/6158/7311/25873/6154/6138/6141/6202/6228/23521/6203/9349/3921/6188/6189/6194/6134/6160/6191/6128/6135/6132/6156/6155/6147/6175/6129/6143/9045/6217/6181/6187/6124/6208/6157/6152/6136/6122/6133/6210/6231/6233/6165/6125/6230/6130 46 Bovine_viral_diarrhea_virus R-HSA-71291 Metabolism of amino acids and derivatives 96/865 372/10654 9.344311907502729e-26 7.965535814857221e-25 4.140799240571692e-25 5716/9491/5715/6142/23198/6158/5718/7311/5711/25873/5689/6154/6138/5701/6141/5688/6202/143471/6228/5706/23521/5687/6203/5705/5684/9349/10197/1728/3921/5720/6188/5685/6189/6194/29968/5683/6134/5698/5708/5692/6160/5686/6191/1373/5713/6128/6135/5682/6132/6156/6155/10213/5709/5694/6147/5699/6175/6129/5695/6143/5710/9045/6217/5700/6181/6187/122706/5707/6124/5702/9380/2954/5693/6208/6157/5721/5696/5719/5691/5714/6152/5690/6136/2936/6122/6133/6210/6231/5704/6233/6165/6125/5717/9861/6230/6130 96 Bovine_viral_diarrhea_virus R-HSA-983169 Class I MHC mediated antigen processing & presentation 95/865 371/10654 3.231524620970748e-25 2.7355753562245433e-24 1.4220598112751392e-24 7322/5716/9491/5715/8454/9354/6500/23198/57154/1147/5718/25793/7311/5711/5689/6047/5701/8945/5688/143471/5706/5687/26270/5705/26259/5684/23291/8065/10197/8517/5720/5685/4615/5683/64750/80204/3309/5698/5708/9690/27246/5692/5686/8452/5713/57531/7323/5682/7334/5930/7316/55294/10213/5709/5694/5699/9978/51320/3551/5695/7319/5710/5700/3107/7321/122706/5707/991/5702/7332/8453/7335/11059/5693/9040/10273/5721/5696/997/51676/5719/10075/5691/9246/9021/5714/5690/8924/9817/9820/7314/5704/6233/5717/9861 95 Bovine_viral_diarrhea_virus R-HSA-6803529 FGFR2 alternative splicing 24/865 26/10654 1.3892197541167521e-24 1.1679026760471179e-23 6.07121809058646e-24 2962/7073/3178/2963/5437/5441/5434/5440/4670/23543/5438/5431/5435/4686/5433/5439/3185/5430/5432/22916/5436/5725/7072/3187 24 Bovine_viral_diarrhea_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 52/865 129/10654 4.733265184360116e-24 3.9519522326951934e-23 2.054380418878724e-23 7322/8454/6500/51135/28512/1147/330/6196/7311/1432/3725/11035/8945/23118/329/1386/351/23291/841/8517/4615/9641/4790/6197/6885/5599/7323/5606/3656/7334/7316/6195/3551/79155/10454/7321/8737/7335/5970/4792/4793/3654/4791/29110/7189/5594/7314/28511/6233/5595/257397/4214 52 Bovine_viral_diarrhea_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 42/865 85/10654 6.972468880492572e-24 5.704321855919762e-23 2.965331166412242e-23 8454/6500/51135/28512/1147/6196/7311/1432/3725/8945/23118/1386/351/23291/8517/4615/4790/6197/6885/5599/5606/3656/7334/7316/6195/3551/79155/10454/7335/5970/4792/4793/3654/4791/7189/5594/7314/28511/6233/5595/257397/4214 42 Bovine_viral_diarrhea_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 42/865 85/10654 6.972468880492572e-24 5.704321855919762e-23 2.965331166412242e-23 8454/6500/51135/28512/1147/6196/7311/1432/3725/8945/23118/1386/351/23291/8517/4615/4790/6197/6885/5599/5606/3656/7334/7316/6195/3551/79155/10454/7335/5970/4792/4793/3654/4791/7189/5594/7314/28511/6233/5595/257397/4214 42 Bovine_viral_diarrhea_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 42/865 85/10654 6.972468880492572e-24 5.704321855919762e-23 2.965331166412242e-23 8454/6500/51135/28512/1147/6196/7311/1432/3725/8945/23118/1386/351/23291/8517/4615/4790/6197/6885/5599/5606/3656/7334/7316/6195/3551/79155/10454/7335/5970/4792/4793/3654/4791/7189/5594/7314/28511/6233/5595/257397/4214 42 Bovine_viral_diarrhea_virus R-HSA-8878171 Transcriptional regulation by RUNX1 71/865 239/10654 4.4180652290573435e-23 3.5904143428139344e-22 1.8664387844859798e-22 5716/9491/5715/23198/5718/7311/5711/1460/5689/27161/5701/5688/25/1387/143471/5706/5687/5705/5684/10197/192670/5720/5685/5683/5698/5708/5692/5686/5713/10138/2033/5579/648/5682/57332/7316/595/10213/5709/5694/5699/6929/5695/23466/1459/5710/5700/122706/5707/5702/3065/1457/5693/5721/5696/6045/5719/5691/9021/10413/5714/5690/5371/23112/2099/6714/7314/5704/6233/5717/9861 71 Bovine_viral_diarrhea_virus R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs 51/865 130/10654 5.753471096932394e-23 4.644689580901052e-22 2.414492576056676e-22 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/25/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/6929/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/10413/5714/5690/7314/5704/6233/5717/9861 51 Bovine_viral_diarrhea_virus R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 47/865 112/10654 9.640500585539866e-23 7.731427772219143e-22 4.0191006596225764e-22 6142/6158/7311/25873/6154/6138/6141/6202/6228/23521/6203/9349/3921/6188/6189/6194/6134/6160/6191/6731/6128/6135/6132/6156/6155/6147/6175/6129/6143/9045/6217/6181/6187/6124/6208/6157/6152/6136/6122/6133/6210/6231/6233/6165/6125/6230/6130 47 Bovine_viral_diarrhea_virus R-HSA-195721 Signaling by WNT 85/865 331/10654 1.038688232938463e-22 8.275561803607754e-22 4.30196295995153e-22 5716/9491/5715/8454/1857/6500/23198/409/7514/57154/5718/79577/7311/5711/1460/5689/27161/2932/5701/8945/1173/5688/1387/143471/5706/5687/5705/5684/387/10197/161/192670/5720/5685/5683/8607/64750/5698/5708/5692/5686/8452/5713/3845/6885/2033/5579/5682/7316/1499/10213/5709/5694/5699/9978/5695/1459/5710/801/5700/122706/5707/5702/3065/1457/5693/207/5721/5696/1452/5719/5691/5714/5690/23112/5578/208/4609/7314/5704/6233/1488/2787/5717/9861 85 Bovine_viral_diarrhea_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 42/865 92/10654 3.5192316898936555e-22 2.785677551935303e-21 1.4481049058892555e-21 8454/6500/51135/28512/1147/6196/7311/1432/3725/8945/23118/1386/351/23291/8517/4615/4790/6197/6885/5599/5606/3656/7334/7316/6195/3551/79155/10454/7335/5970/4792/4793/3654/4791/7189/5594/7314/28511/6233/5595/257397/4214 42 Bovine_viral_diarrhea_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 42/865 93/10654 5.9302544910635725e-22 4.633961682440061e-21 2.4089157919165122e-21 8454/6500/51135/28512/1147/6196/7311/1432/3725/8945/23118/1386/351/23291/8517/4615/4790/6197/6885/5599/5606/3656/7334/7316/6195/3551/79155/10454/7335/5970/4792/4793/3654/4791/7189/5594/7314/28511/6233/5595/257397/4214 42 Bovine_viral_diarrhea_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 42/865 93/10654 5.9302544910635725e-22 4.633961682440061e-21 2.4089157919165122e-21 8454/6500/51135/28512/1147/6196/7311/1432/3725/8945/23118/1386/351/23291/8517/4615/4790/6197/6885/5599/5606/3656/7334/7316/6195/3551/79155/10454/7335/5970/4792/4793/3654/4791/7189/5594/7314/28511/6233/5595/257397/4214 42 Bovine_viral_diarrhea_virus R-HSA-5683057 MAPK family signaling cascades 78/865 294/10654 7.538822245775612e-22 5.853391285095841e-21 3.0428233268232777e-21 5716/9491/5715/23198/409/7514/5718/7311/5711/5689/27161/8826/3725/5701/5688/143471/5706/2064/5687/5921/5705/5684/3717/1956/10197/192670/5720/5685/5683/5698/5708/5692/5686/8452/5713/2335/3845/408/5682/7316/10213/5709/5694/3265/5699/9978/5695/5710/801/5700/10642/122706/5707/7297/5702/5567/4233/983/5693/5721/5696/5719/5691/5714/5690/5245/23112/6714/5594/4609/7314/5704/6233/5568/5595/5717/9861/5566 78 Bovine_viral_diarrhea_virus R-HSA-201681 TCF dependent signaling in response to WNT 68/865 233/10654 1.1553430522493637e-21 8.913691017037813e-21 4.6336876579221656e-21 5716/9491/5715/1857/23198/7514/5718/79577/7311/5711/1460/5689/2932/5701/8945/5688/1387/143471/5706/5687/5705/5684/10197/5720/5685/5683/8607/64750/5698/5708/5692/5686/8452/5713/2033/5682/7316/1499/10213/5709/5694/5699/9978/5695/1459/5710/5700/122706/5707/5702/3065/1457/5693/207/5721/5696/1452/5719/5691/5714/5690/208/4609/7314/5704/6233/5717/9861 68 Bovine_viral_diarrhea_virus R-HSA-2408522 Selenoamino acid metabolism 47/865 118/10654 1.3823834657634126e-21 1.0598273237519497e-20 5.509399843691324e-21 6142/6158/7311/25873/6154/6138/6141/6202/6228/23521/6203/9349/3921/6188/6189/6194/6134/6160/6191/6128/6135/6132/6156/6155/6147/6175/6129/6143/9045/6217/6181/6187/6124/6208/6157/6152/6136/2936/6122/6133/6210/6231/6233/6165/6125/6230/6130 47 Bovine_viral_diarrhea_virus R-HSA-77595 Processing of Intronless Pre-mRNAs 19/865 19/10654 1.5887883440692665e-21 1.2104581196377725e-20 6.2924380469059106e-21 10898/29894/53981/10914/81608/4686/8189/51692/11051/1477/23283/10978/79869/22916/1479/51585/1478/55339/8106 19 Bovine_viral_diarrhea_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 42/865 95/10654 1.6408426319523313e-21 1.2346834372530198e-20 6.4183707890533045e-21 8454/6500/51135/28512/1147/6196/7311/1432/3725/8945/23118/1386/351/23291/8517/4615/4790/6197/6885/5599/5606/3656/7334/7316/6195/3551/79155/10454/7335/5970/4792/4793/3654/4791/7189/5594/7314/28511/6233/5595/257397/4214 42 Bovine_viral_diarrhea_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 42/865 95/10654 1.6408426319523313e-21 1.2346834372530198e-20 6.4183707890533045e-21 8454/6500/51135/28512/1147/6196/7311/1432/3725/8945/23118/1386/351/23291/8517/4615/4790/6197/6885/5599/5606/3656/7334/7316/6195/3551/79155/10454/7335/5970/4792/4793/3654/4791/7189/5594/7314/28511/6233/5595/257397/4214 42 Bovine_viral_diarrhea_virus R-HSA-69620 Cell Cycle Checkpoints 77/865 293/10654 2.640441241116222e-21 1.9746612717304753e-20 1.0265067014219993e-20 5716/9491/5715/672/23198/7514/5718/1017/7311/5711/9184/5689/7341/5701/5688/11200/143471/5706/5687/5705/5684/10197/5720/5685/54908/5683/5698/5708/580/5983/5692/5985/5686/5713/5682/7334/1781/7316/10213/5709/57060/5694/5699/4174/7531/5695/5501/7465/1783/5710/5700/7321/122706/5707/8655/991/5702/7157/983/5693/5721/10971/140735/5696/5719/5691/5714/5690/8924/4171/1063/7314/5704/6233/1778/5717/9861 77 Bovine_viral_diarrhea_virus R-HSA-156590 Glutathione conjugation 26/865 36/10654 3.6088614261566394e-21 2.6824402917591118e-20 1.394438112032283e-20 2949/2944/2939/2940/373156/4257/10327/2947/2937/2687/4259/2686/221357/494143/119391/4258/2938/27306/2954/2941/2946/653689/2948/2678/9446/2950 26 Bovine_viral_diarrhea_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 42/865 97/10654 4.3930835810089036e-21 3.2455569001514264e-20 1.687168303519847e-20 8454/6500/51135/28512/1147/6196/7311/1432/3725/8945/23118/1386/351/23291/8517/4615/4790/6197/6885/5599/5606/3656/7334/7316/6195/3551/79155/10454/7335/5970/4792/4793/3654/4791/7189/5594/7314/28511/6233/5595/257397/4214 42 Bovine_viral_diarrhea_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 42/865 98/10654 7.104173212264442e-21 5.185621045359494e-20 2.695690055961673e-20 8454/6500/51135/28512/1147/6196/7311/1432/3725/8945/23118/1386/351/23291/8517/4615/4790/6197/6885/5599/5606/3656/7334/7316/6195/3551/79155/10454/7335/5970/4792/4793/3654/4791/7189/5594/7314/28511/6233/5595/257397/4214 42 Bovine_viral_diarrhea_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 42/865 98/10654 7.104173212264442e-21 5.185621045359494e-20 2.695690055961673e-20 8454/6500/51135/28512/1147/6196/7311/1432/3725/8945/23118/1386/351/23291/8517/4615/4790/6197/6885/5599/5606/3656/7334/7316/6195/3551/79155/10454/7335/5970/4792/4793/3654/4791/7189/5594/7314/28511/6233/5595/257397/4214 42 Bovine_viral_diarrhea_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 37/865 78/10654 2.1054092233981973e-20 1.5276749067395254e-19 7.941455842642323e-20 7322/28512/1147/7128/7311/84282/1387/5094/351/841/7706/8517/5300/9641/7186/4790/2033/7323/64135/7316/1540/3551/7321/8737/5970/4792/4793/9246/4791/29110/7189/57506/7314/28511/6233/4214/23586 37 Bovine_viral_diarrhea_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 33/865 63/10654 4.68842261427842e-20 3.3817675543227183e-19 1.7579759662383116e-19 28512/1147/7311/170506/11035/1387/5437/5441/5434/5440/81030/8517/4615/4790/5591/2033/5435/7316/1499/3551/2547/8737/1660/5970/4792/4793/4791/29110/81844/7314/28511/7520/6233 33 Bovine_viral_diarrhea_virus R-HSA-9607240 FLT3 Signaling 71/865 267/10654 5.00238958083982e-20 3.5870075876727885e-19 1.86466781898797e-19 5295/5716/9491/5715/23198/409/5718/7311/5711/5689/5170/8826/5701/5688/143471/5706/2064/5687/5921/5705/5684/3717/1956/10197/5290/5720/5685/5683/5698/5708/5692/5686/8452/5713/2335/3845/408/5682/5291/7316/10213/5709/5694/3265/5699/9978/5695/5710/801/5700/122706/5707/5702/4233/5693/5721/5696/5719/5691/5714/5690/5245/6714/5594/208/7314/5704/6233/5595/5717/9861 71 Bovine_viral_diarrhea_virus R-HSA-168898 Toll-like Receptor Cascades 52/865 155/10654 8.644888510808559e-20 6.1626427454243475e-19 3.2035844158244095e-19 7322/8454/6500/51135/28512/1147/330/6196/7311/1432/3725/11035/8945/23118/329/1386/351/23291/841/8517/4615/9641/4790/6197/6885/5599/7323/5606/3656/7334/7316/6195/3551/79155/10454/7321/8737/7335/5970/4792/4793/3654/4791/29110/7189/5594/7314/28511/6233/5595/257397/4214 52 Bovine_viral_diarrhea_virus R-HSA-8868773 rRNA processing in the nucleus and cytosol 59/865 195/10654 8.823827570751206e-20 6.253631284154488e-19 3.2508838418557077e-19 6142/6158/5393/55623/7311/25873/83732/6154/6138/6141/11056/6202/6228/2091/23521/6203/9349/3921/6188/6189/90459/6194/6134/6160/6191/26354/6128/6135/6132/6156/6155/6147/6175/8568/6129/6143/9045/6217/6181/6187/55226/4691/6124/27292/6208/6157/10969/6152/6136/6122/6133/6210/6231/10528/6233/6165/6125/6230/6130 59 Bovine_viral_diarrhea_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 24/865 33/10654 9.484703124246687e-20 6.683152085813128e-19 3.4741656713091e-19 28512/1147/7311/23118/351/8517/4790/6885/3656/7334/7316/3551/10454/7335/5970/4792/4793/3654/4791/7189/7314/28511/6233/257397 24 Bovine_viral_diarrhea_virus R-HSA-5654738 Signaling by FGFR2 35/865 73/10654 1.4681530044624783e-19 1.0285508692182535e-18 5.346812514739335e-19 5295/2962/7073/7311/3178/2963/5437/5441/5434/5440/4670/5290/23543/5438/5431/3845/5435/4686/7316/3265/5433/5439/3185/5430/5432/22916/5436/5725/7072/6714/5594/7314/6233/5595/3187 35 Bovine_viral_diarrhea_virus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 30/865 54/10654 2.536904766200711e-19 1.767135377142095e-18 9.186265679716258e-19 10450/9318/7311/56949/5437/6917/5441/5434/5440/8533/5438/9716/5431/2033/8450/5435/7316/9978/5433/27339/5439/10987/2071/5430/5432/91603/5436/7314/6233/2873 30 Bovine_viral_diarrhea_virus R-HSA-5684996 MAPK1/MAPK3 signaling 68/865 255/10654 2.710701576831306e-19 1.877468876225774e-18 9.759822662993102e-19 5716/9491/5715/23198/409/5718/7311/5711/5689/8826/5701/5688/143471/5706/2064/5687/5921/5705/5684/3717/1956/10197/5720/5685/5683/5698/5708/5692/5686/8452/5713/2335/3845/408/5682/7316/10213/5709/5694/3265/5699/9978/5695/5710/801/5700/122706/5707/7297/5702/4233/983/5693/5721/5696/5719/5691/5714/5690/5245/6714/5594/7314/5704/6233/5595/5717/9861 68 Bovine_viral_diarrhea_virus R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 56/865 185/10654 7.676186399865121e-19 5.286593910415583e-18 2.7481797280516224e-18 6142/6158/5393/7311/25873/83732/6154/6138/6141/11056/6202/6228/2091/23521/6203/9349/3921/6188/6189/90459/6194/6134/6160/6191/26354/6128/6135/6132/6156/6155/6147/6175/8568/6129/6143/9045/6217/6181/6187/4691/6124/6208/6157/10969/6152/6136/6122/6133/6210/6231/10528/6233/6165/6125/6230/6130 56 Bovine_viral_diarrhea_virus R-HSA-450294 MAP kinase activation 32/865 64/10654 1.0862327711897883e-18 7.438863753260404e-18 3.86701435988322e-18 8454/6500/1147/6196/7311/1432/3725/8945/23118/1386/23291/8517/4790/6197/6885/5599/5606/3656/7334/7316/6195/3551/79155/10454/7335/3654/7189/5594/7314/6233/5595/257397 32 Bovine_viral_diarrhea_virus R-HSA-72312 rRNA processing 59/865 205/10654 1.3145769976717032e-18 8.950041972589827e-18 4.652584316306788e-18 6142/6158/5393/55623/7311/25873/83732/6154/6138/6141/11056/6202/6228/2091/23521/6203/9349/3921/6188/6189/90459/6194/6134/6160/6191/26354/6128/6135/6132/6156/6155/6147/6175/8568/6129/6143/9045/6217/6181/6187/55226/4691/6124/27292/6208/6157/10969/6152/6136/6122/6133/6210/6231/10528/6233/6165/6125/6230/6130 59 Bovine_viral_diarrhea_virus R-HSA-5673001 RAF/MAP kinase cascade 66/865 249/10654 1.3215812592831573e-18 8.950041972589827e-18 4.652584316306788e-18 5716/9491/5715/23198/409/5718/7311/5711/5689/8826/5701/5688/143471/5706/2064/5687/5921/5705/5684/3717/1956/10197/5720/5685/5683/5698/5708/5692/5686/8452/5713/2335/3845/408/5682/7316/10213/5709/5694/3265/5699/9978/5695/5710/801/5700/122706/5707/5702/4233/5693/5721/5696/5719/5691/5714/5690/5245/6714/5594/7314/5704/6233/5595/5717/9861 66 Bovine_viral_diarrhea_virus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 35/865 79/10654 3.596507476170289e-18 2.422178239476012e-17 1.2591436467894818e-17 10450/9318/7311/56949/5437/6917/5441/5434/5440/8533/5438/5983/9716/5431/5985/2033/8450/5435/7316/5981/9978/5433/27339/5439/10987/2071/5430/5424/5432/91603/5436/5111/7314/6233/2873 35 Bovine_viral_diarrhea_virus R-HSA-68886 M Phase 86/865 395/10654 5.7617101972461795e-18 3.8590795222214796e-17 2.0061015261666862e-17 5716/9491/5715/23198/4000/7514/5718/7311/5711/9184/1460/9883/5689/7277/5701/84617/5688/143471/5706/5687/5705/10383/5684/10197/5720/5685/54908/5683/5698/5708/3320/5692/5686/5713/5579/5885/5682/8243/1781/9126/7316/10213/5709/5694/10426/5699/7531/5695/5501/1459/1783/5710/5700/7321/122706/5707/8655/991/5702/203068/1457/983/7112/5693/1639/5721/140735/5696/10592/7280/5719/5691/2801/5714/5690/5578/5594/1063/7314/5704/6233/5595/1778/5717/9861/5566 86 Bovine_viral_diarrhea_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 29/865 55/10654 6.988224097804034e-18 4.6549973635099e-17 2.41985096743056e-17 7295/1147/330/7128/7311/1432/23118/329/351/841/8517/598/4790/6885/3656/7334/7316/1540/3551/10454/7335/5970/3654/4791/7189/7314/6233/257397/3326 29 Bovine_viral_diarrhea_virus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 31/865 65/10654 2.1892952931792016e-17 1.450408131731221e-16 7.539792714495878e-17 10450/7311/56949/5437/6917/5441/5434/5440/5438/5983/9716/5431/5985/2033/8450/5435/7316/5981/9978/5433/27339/5439/2071/5430/5424/5432/91603/5436/5111/7314/6233 31 Bovine_viral_diarrhea_virus R-HSA-6782135 Dual incision in TC-NER 31/865 66/10654 3.8143631077304717e-17 2.51335601530997e-16 1.3065414457204802e-16 10450/7311/56949/5437/6917/5441/5434/5440/5438/5983/9716/5431/5985/2033/8450/5435/7316/5981/9978/5433/27339/5439/2071/5430/5424/5432/91603/5436/5111/7314/6233 31 Bovine_viral_diarrhea_virus R-HSA-72202 Transport of Mature Transcript to Cytoplasm 35/865 84/10654 3.9204208190928534e-17 2.5693510636958e-16 1.3356498772461223e-16 10921/10898/29894/9883/53981/7919/199746/10250/10569/6432/8683/6431/9775/10189/6430/51362/55110/9295/22794/81608/6427/4686/9785/7884/8189/51692/11338/6426/4116/22916/65109/9939/6429/6428/55339 35 Bovine_viral_diarrhea_virus R-HSA-933542 TRAF6 mediated NF-kB activation 19/865 24/10654 4.559369046856982e-17 2.9721234588869843e-016 1.545026831527106e-16 28512/1147/84282/351/7706/8517/7186/4790/64135/3551/5970/4792/4793/4791/7189/57506/28511/4214/23586 19 Bovine_viral_diarrhea_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 21/865 30/10654 7.072114038672858e-17 4.585588836777773e-16 2.3837696815683433e-16 7124/1147/330/7128/7311/7132/23118/329/8517/7186/6885/7316/1540/3551/7185/10454/8737/55072/7314/6233/257397 21 Bovine_viral_diarrhea_virus R-HSA-448424 Interleukin-17 signaling 32/865 72/10654 8.977296703214395e-17 5.790118878951507e-16 3.009931838114768e-16 8454/6500/1147/6196/7311/1432/3725/8945/23118/1386/23291/8517/4790/6197/6885/5599/5606/3656/7334/7316/6195/3551/79155/10454/7335/3654/7189/5594/7314/6233/5595/257397 32 Bovine_viral_diarrhea_virus R-HSA-190236 Signaling by FGFR 35/865 87/10654 1.4830207496802563e-16 9.514748915053854e-16 4.946141226080412e-16 5295/2962/7073/7311/3178/2963/5437/5441/5434/5440/4670/5290/23543/5438/5431/3845/5435/4686/7316/3265/5433/5439/3185/5430/5432/22916/5436/5725/7072/6714/5594/7314/6233/5595/3187 35 Bovine_viral_diarrhea_virus R-HSA-5619115 Disorders of transmembrane transporters 51/865 176/10654 2.2353552037291047e-16 1.4266481640553816e-15 7.416279044612406e-16 5716/9491/5715/23198/5718/7311/5711/9883/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/213/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/7415/5717/9861 51 Bovine_viral_diarrhea_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 17/865 20/10654 2.255897341066629e-16 1.432259822270948e-15 7.445450654178239e-16 7322/1147/330/7311/11035/329/8517/7323/7334/7316/3551/7321/8737/7335/7189/7314/6233 17 Bovine_viral_diarrhea_virus R-HSA-205043 NRIF signals cell death from the nucleus 15/865 16/10654 5.80933604830544e-16 3.669212768333851e-15 1.907401309560881e-15 7311/4804/23385/5599/55851/51107/7316/4803/5663/7189/8878/7314/5664/83464/6233 15 Bovine_viral_diarrhea_virus R-HSA-5696398 Nucleotide Excision Repair 39/865 111/10654 6.345679663771749e-16 3.987311087699877e-15 2.072761344324793e-15 10450/9318/7311/7341/56949/5437/6917/5441/5434/5440/8533/5438/8607/5983/9716/5431/5985/2033/8450/5435/7334/7316/5981/9978/5433/27339/5439/10987/2071/5430/5424/5432/91603/5436/7329/5111/7314/6233/2873 39 Bovine_viral_diarrhea_virus R-HSA-168638 NOD1/2 Signaling Pathway 22/865 36/10654 1.0036500028200886e-15 6.2740992483984e-15 3.2615238958040136e-15 1147/330/7128/7311/1432/23118/329/841/8517/6885/3656/7334/7316/1540/3551/10454/7335/3654/7189/7314/6233/257397 22 Bovine_viral_diarrhea_virus R-HSA-8851708 Signaling by FGFR2 IIIa TM 16/865 19/10654 2.4040641500211725e-15 1.4951807137121477e-14 7.772538229391762e-15 2962/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 16 Bovine_viral_diarrhea_virus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 15/865 17/10654 4.568162698804264e-15 2.826695598904771e-14 1.4694277022068755e-14 28512/1147/11035/81030/8517/4615/4790/3551/8737/1660/5970/4792/4793/4791/28511 15 Bovine_viral_diarrhea_virus R-HSA-209560 NF-kB is activated and signals survival 13/865 13/10654 6.1287705935637536e-15 3.7732178553304117e-14 1.9614672500400744e-14 7311/4804/4790/7316/4803/3551/5970/4792/3654/7189/8878/7314/6233 13 Bovine_viral_diarrhea_virus R-HSA-211859 Biological oxidations 56/865 222/10654 6.2702243201568725e-015 3.840906254407652e-14 1.9966543457997552e-14 1543/2949/1576/2944/29785/1553/2939/124/2940/6916/1572/7360/373156/4257/10327/2947/126/130/2937/2687/1548/4259/1577/2686/221357/5740/1571/5742/494143/1545/119391/1558/1557/4258/2938/2052/27306/2954/2941/127/6256/2946/128/653689/218/1562/1559/2948/125/2678/10728/9446/1555/2950/3326/1544 56 Bovine_viral_diarrhea_virus R-HSA-73887 Death Receptor Signalling 43/865 141/10654 7.0678829408835505e-15 4.307874652468524e-14 2.2394029107431045e-14 7124/1147/330/7128/7311/7132/4804/23118/23385/329/387/841/8841/8517/4615/7186/4790/6885/5599/55851/51107/7316/1540/4803/7531/3551/7185/10454/3065/3066/8737/5970/4792/55072/5663/3654/7189/8878/7314/5664/83464/6233/257397 43 Bovine_viral_diarrhea_virus R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 17/865 23/10654 1.5797611609576005e-14 9.580740573170722e-14 4.980446289062454e-14 2962/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436/25920 17 Bovine_viral_diarrhea_virus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 16/865 21/10654 4.3190742945480834e-14 2.606411665868373e-13 1.3549154378936665e-13 28512/1147/11035/81030/8517/4615/4790/3551/8737/1660/5970/4792/4793/4791/29110/28511 16 Bovine_viral_diarrhea_virus R-HSA-193639 p75NTR signals via NF-kB 14/865 16/10654 5.042363995229509e-14 3.027902320288065e-13 1.5740228805435129e-13 7311/4804/4615/4790/7316/4803/3551/5970/4792/3654/7189/8878/7314/6233 14 Bovine_viral_diarrhea_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 26/865 58/10654 5.529344906508232e-14 3.2405151158815074e-13 1.6845473854847954e-13 10014/8454/6500/22938/7311/1387/23385/8841/2033/55851/51107/7316/55294/9978/9611/3065/3066/23462/9759/9612/5663/4609/7314/5664/83464/6233 26 Bovine_viral_diarrhea_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 26/865 58/10654 5.529344906508232e-14 3.2405151158815074e-13 1.6845473854847954e-13 10014/8454/6500/22938/7311/1387/23385/8841/2033/55851/51107/7316/55294/9978/9611/3065/3066/23462/9759/9612/5663/4609/7314/5664/83464/6233 26 Bovine_viral_diarrhea_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 26/865 58/10654 5.529344906508232e-14 3.2405151158815074e-13 1.6845473854847954e-13 10014/8454/6500/22938/7311/1387/23385/8841/2033/55851/51107/7316/55294/9978/9611/3065/3066/23462/9759/9612/5663/4609/7314/5664/83464/6233 26 Bovine_viral_diarrhea_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 26/865 58/10654 5.529344906508232e-14 3.2405151158815074e-13 1.6845473854847954e-13 10014/8454/6500/22938/7311/1387/23385/8841/2033/55851/51107/7316/55294/9978/9611/3065/3066/23462/9759/9612/5663/4609/7314/5664/83464/6233 26 Bovine_viral_diarrhea_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 26/865 58/10654 5.529344906508232e-14 3.2405151158815074e-13 1.6845473854847954e-13 10014/8454/6500/22938/7311/1387/23385/8841/2033/55851/51107/7316/55294/9978/9611/3065/3066/23462/9759/9612/5663/4609/7314/5664/83464/6233 26 Bovine_viral_diarrhea_virus R-HSA-5689896 Ovarian tumor domain proteases 21/865 38/10654 7.579925372584113e-14 4.42101867424882e-13 2.2982196294614135e-13 7128/7311/84282/387/7706/8517/64135/7316/79155/7321/8737/7157/983/7189/55611/2099/57506/7314/6233/7415/23586 21 Bovine_viral_diarrhea_virus R-HSA-1980143 Signaling by NOTCH1 29/865 73/10654 8.991555871059394e-14 5.219384098486381e-13 2.71324142074073e-13 10014/8454/6500/22938/409/7311/3091/1387/23385/8841/2033/408/55851/51107/7316/55294/9978/9611/3065/3066/23462/9759/9612/5663/4609/7314/5664/83464/6233 29 Bovine_viral_diarrhea_virus R-HSA-937041 IKK complex recruitment mediated by RIP1 17/865 25/10654 1.4475746147866972e-13 8.363002158412245e-13 4.347417900232436e-13 7322/1147/330/7311/11035/329/8517/7323/7334/7316/3551/7321/8737/7335/7189/7314/6233 17 Bovine_viral_diarrhea_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 87/865 473/10654 1.524550234242941e-13 8.766163846896911e-13 4.556997224499755e-13 2475/5295/2962/7073/6196/7311/3178/5170/1432/23118/1173/2963/3932/23385/5437/2064/5921/5441/5434/5440/4670/5590/3717/387/8065/1956/161/5290/4914/529/23543/5438/581/348/3320/5431/2335/6197/3845/5579/55851/5435/51107/5770/4686/5291/7316/6195/1499/4803/3265/5433/9611/801/5439/5567/3185/5430/11059/5432/4233/22916/5663/10273/207/5436/5725/11140/10413/7072/5578/6772/2099/6714/5594/208/7314/5664/83464/6233/5568/7525/5595/3187/25920/5580/5566 87 Bovine_viral_diarrhea_virus R-HSA-75893 TNF signaling 22/865 43/10654 1.602503378304528e-13 9.171134357526852e-13 4.767516845758962e-13 7124/1147/330/7128/7311/7132/23118/329/841/8517/7186/6885/7316/1540/3551/7185/10454/8737/55072/7314/6233/257397 22 Bovine_viral_diarrhea_virus R-HSA-72766 Translation 63/865 291/10654 2.626079883229922e-13 1.4958838213351752e-12 7.776193259736415e-13 6142/6158/7311/25873/6154/3646/6138/6141/26986/6202/6228/23521/6203/9349/3921/6188/6189/6194/8894/6134/1965/6160/27335/6191/6731/6128/6135/6132/6156/65993/6155/1938/6147/56945/6175/6129/6143/1915/9045/6217/6181/6187/6124/1936/6208/51073/6157/51116/7284/8892/6152/6136/6122/6133/6210/6231/8668/6233/6165/6125/55168/6230/6130 63 Bovine_viral_diarrhea_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 19/865 34/10654 9.082282938767212e-13 5.149443210398712e-12 2.6768833924787574e-12 7322/7128/7311/84282/5094/7706/5300/9641/7323/64135/7316/1540/7321/9246/29110/57506/7314/6233/23586 19 Bovine_viral_diarrhea_virus R-HSA-203927 MicroRNA (miRNA) biogenesis 16/865 24/10654 1.2353930481428382e-12 6.9398346805811974e-12 3.6075993935580343e-12 27161/5437/5441/5434/5440/8575/192670/5438/5431/5435/5433/5439/5430/5901/5432/5436 16 Bovine_viral_diarrhea_virus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 16/865 24/10654 1.2353930481428382e-12 6.9398346805811974e-12 3.6075993935580343e-12 7311/1432/23118/8517/6885/5606/3656/7334/7316/10454/7335/3654/7189/7314/6233/257397 16 Bovine_viral_diarrhea_virus R-HSA-8939211 ESR-mediated signaling 52/865 223/10654 1.6902680833814866e-12 9.45154492496345e-12 4.9132853027313145e-12 5295/2962/7514/1025/5170/27161/3725/1387/2963/5437/3838/5441/5434/5440/5590/1386/1956/5290/192670/5438/3320/5431/3845/2033/5885/5435/904/8243/9126/595/3265/5433/1509/801/5439/1655/3065/5430/5432/207/5436/6667/23112/2099/6714/5594/208/10728/4609/5595/2787/3326 52 Bovine_viral_diarrhea_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 13/865 16/10654 2.722312504708517e-12 1.5152963211140102e-11 7.87710707923349e-12 8454/6500/1147/7311/8945/23291/8517/4790/7316/3551/79155/7314/6233 13 Bovine_viral_diarrhea_virus R-HSA-9006931 Signaling by Nuclear Receptors 62/865 299/10654 3.041931521211698e-12 1.685506601980482e-11 8.76192715679159e-12 5295/2962/7514/1025/5170/27161/124/3725/1387/2963/5437/3838/5441/5434/5440/8644/5590/1386/126/1956/8841/5290/192670/5438/1374/348/3320/5431/3845/2033/5885/5435/904/8243/9126/595/3265/5433/1509/9611/801/5439/1655/3065/5430/5432/127/9612/207/6256/5436/6667/23112/2099/6714/5594/208/10728/4609/5595/2787/3326 62 Bovine_viral_diarrhea_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 27/865 73/10654 4.859251720270755e-12 2.680284093669706e-11 1.3933172353431744e-11 22938/7514/57154/1025/7311/5590/387/4088/7040/64750/7323/904/7316/9611/7027/5501/7321/3065/9612/9040/10273/4087/6667/4738/4609/7314/6233 27 Bovine_viral_diarrhea_virus R-HSA-72086 mRNA Capping 17/865 29/10654 5.081202366560729e-12 2.7900836418187065e-11 1.4503953649452627e-11 2962/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/2071/5430/5432/22916/5436 17 Bovine_viral_diarrhea_virus R-HSA-113418 Formation of the Early Elongation Complex 18/865 33/10654 6.387736971359583e-12 3.460733941372147e-11 1.7990258043314477e-11 2962/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/2071/5430/5432/22916/5436/25920 18 Bovine_viral_diarrhea_virus R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 18/865 33/10654 6.387736971359583e-12 3.460733941372147e-11 1.7990258043314477e-11 2962/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/2071/5430/5432/22916/5436/25920 18 Bovine_viral_diarrhea_virus R-HSA-5357905 Regulation of TNFR1 signaling 18/865 33/10654 6.387736971359583e-12 3.460733941372147e-11 1.7990258043314477e-11 7124/1147/330/7128/7311/7132/329/841/8517/7186/7316/1540/3551/7185/8737/55072/7314/6233 18 Bovine_viral_diarrhea_virus R-HSA-167169 HIV Transcription Elongation 21/865 46/10654 9.748244509237513e-12 5.211890375772162e-11 2.7093458885323102e-11 2962/1025/2963/5437/6917/5441/5434/5440/5438/5431/5435/904/4686/5433/5439/2071/5430/5432/22916/5436/25920 21 Bovine_viral_diarrhea_virus R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 21/865 46/10654 9.748244509237513e-12 5.211890375772162e-11 2.7093458885323102e-11 2962/1025/2963/5437/6917/5441/5434/5440/5438/5431/5435/904/4686/5433/5439/2071/5430/5432/22916/5436/25920 21 Bovine_viral_diarrhea_virus R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 21/865 46/10654 9.748244509237513e-12 5.211890375772162e-11 2.7093458885323102e-11 2962/1025/2963/5437/6917/5441/5434/5440/5438/5431/5435/904/4686/5433/5439/2071/5430/5432/22916/5436/25920 21 Bovine_viral_diarrhea_virus R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 27/865 75/10654 1.0207731273610924e-11 5.4337224552540245e-11 2.824662940341888e-11 10921/9883/7919/199746/10250/10569/6432/8683/6431/9775/10189/6430/51362/55110/9295/22794/6427/4686/9785/11338/6426/4116/22916/65109/9939/6429/6428 27 Bovine_viral_diarrhea_virus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 15/865 23/10654 1.0328299939311554e-11 5.4739989678351236e-11 2.8456002578789733e-11 7311/23118/8517/6885/5599/3656/7334/7316/10454/7335/3654/7189/7314/6233/257397 15 Bovine_viral_diarrhea_virus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 10/865 10/10654 1.1862945401281943e-11 6.260143049421077e-11 3.2542689139082846e-11 7311/23118/6885/3656/7316/10454/7189/7314/6233/257397 10 Bovine_viral_diarrhea_virus R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 18/865 34/10654 1.2552184233527921e-11 6.56700110758392e-11 3.413785818199146e-11 2962/1025/2963/5437/6917/5441/5434/5440/5438/5431/5435/904/5433/5439/5430/5432/5436/25920 18 Bovine_viral_diarrhea_virus R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 18/865 34/10654 1.2552184233527921e-11 6.56700110758392e-11 3.413785818199146e-11 2962/1025/2963/5437/6917/5441/5434/5440/5438/5431/5435/904/5433/5439/5430/5432/5436/25920 18 Bovine_viral_diarrhea_virus R-HSA-3700989 Transcriptional Regulation by TP53 69/865 365/10654 1.625567599846903e-11 8.449923589132295e-11 4.392603083336334e-11 2475/672/2962/9377/7295/1025/1017/7311/1460/5170/27161/1432/3725/6881/11200/1387/2963/5437/6917/5441/5434/5440/1386/51499/4513/192670/5300/5438/581/580/5983/5431/5985/2877/7001/2033/5435/904/7316/57060/5433/7531/7027/1459/5439/2539/3065/3066/2071/5430/7157/1107/1457/5432/983/207/10971/5436/6790/5371/23112/5111/2936/208/8148/7314/6233/25920/4869 69 Bovine_viral_diarrhea_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 21/865 47/10654 1.628984449094413e-11 8.449923589132295e-11 4.392603083336334e-11 10014/8454/6500/22938/7311/3091/1387/8841/2033/7316/55294/9978/9611/3065/3066/23462/9759/9612/4609/7314/6233 21 Bovine_viral_diarrhea_virus R-HSA-73894 DNA Repair 65/865 334/10654 1.7391391059469985e-11 8.983095636226234e-11 4.669766912489265e-11 10450/672/9318/1017/7311/7014/83932/6047/22976/7341/11200/25/25913/56949/5437/3838/6917/5441/5434/5440/7706/8533/51567/5438/8607/580/5983/9716/5429/5431/5985/5599/5591/2033/8450/5435/7334/7316/5981/9978/5433/322/328/27339/2547/5439/55666/10987/2071/5430/7157/5424/5432/91603/5436/7329/9246/5111/8924/9100/7314/7520/6233/7415/2873 65 Bovine_viral_diarrhea_virus R-HSA-5655253 Signaling by FGFR2 in disease 20/865 43/10654 1.991215022608979e-11 1.0241734652153355e-10 5.324057044684013e-11 5295/2962/2963/5437/5441/5434/5440/5290/5438/5431/3845/5435/4686/3265/5433/5439/5430/5432/22916/5436 20 Bovine_viral_diarrhea_virus R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 21/865 48/10654 2.677099114534067e-11 1.3711696725281628e-10 7.127879995353863e-11 2962/1025/2963/5437/6917/5441/5434/5440/5438/5431/5435/904/4686/5433/5439/2071/5430/5432/22916/5436/25920 21 Bovine_viral_diarrhea_virus R-HSA-167287 HIV elongation arrest and recovery 18/865 36/10654 4.419904101751614e-11 2.2449429583480073e-10 1.1670097672168736e-10 2962/1025/2963/5437/6917/5441/5434/5440/5438/5431/5435/904/5433/5439/5430/5432/5436/25920 18 Bovine_viral_diarrhea_virus R-HSA-167290 Pausing and recovery of HIV elongation 18/865 36/10654 4.419904101751614e-11 2.2449429583480073e-10 1.1670097672168736e-10 2962/1025/2963/5437/6917/5441/5434/5440/5438/5431/5435/904/5433/5439/5430/5432/5436/25920 18 Bovine_viral_diarrhea_virus R-HSA-209543 p75NTR recruits signalling complexes 11/865 13/10654 6.37976886055185e-11 3.2269453282210395e-10 1.6774932754104451e-10 7311/4804/4615/7316/4803/3551/3654/7189/8878/7314/6233 11 Bovine_viral_diarrhea_virus R-HSA-1227986 Signaling by ERBB2 21/865 50/10654 6.902825067245011e-11 3.477084197095731e-10 1.8075253112142225e-10 5295/7311/2064/387/8065/1956/5290/3320/3845/7316/3265/10273/207/11140/5578/6714/208/7314/6233/7525/5580 21 Bovine_viral_diarrhea_virus R-HSA-193692 Regulated proteolysis of p75NTR 10/865 11/10654 1.2096325781498771e-10 6.068074538126339e-10 3.1544241370856665e-10 4804/23385/4790/55851/51107/5970/5663/7189/5664/83464 10 Bovine_viral_diarrhea_virus R-HSA-1236394 Signaling by ERBB4 22/865 58/10654 2.630540754645991e-10 1.3141922868497799e-9 6.831689103955508e-10 5295/7311/23118/23385/1956/5290/348/3845/55851/51107/7316/3265/9611/11059/5663/10413/2099/6714/7314/5664/83464/6233 22 Bovine_viral_diarrhea_virus R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 15/865 27/10654 2.6839617162911947e-10 1.3299794033166528e-9 6.913756753133501e-10 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/2071/5430/5432/5436 15 Bovine_viral_diarrhea_virus R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 15/865 27/10654 2.6839617162911947e-10 1.3299794033166528e-9 6.913756753133501e-10 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/2071/5430/5432/5436 15 Bovine_viral_diarrhea_virus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 23/865 65/10654 5.237259199837374e-10 2.584704034251724e-9 1.3436309560204984e-9 672/2962/1025/3725/2963/5437/6917/5441/5434/5440/1386/5438/5431/5435/904/5433/5439/2071/5430/7157/5432/5436/25920 23 Bovine_viral_diarrhea_virus R-HSA-9018519 Estrogen-dependent gene expression 37/865 150/10654 5.348247881009741e-10 2.6288363576414815e-9 1.3665726758777013e-9 2962/1025/27161/3725/1387/2963/5437/3838/5441/5434/5440/1386/192670/5438/3320/5431/2033/5885/5435/904/8243/9126/595/5433/1509/5439/1655/3065/5430/5432/5436/6667/23112/2099/10728/4609/3326 37 Bovine_viral_diarrhea_virus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 10/865 12/10654 6.728101260363038e-10 3.293797364009053e-9 1.7122455965920732e-9 1147/84282/841/7706/8517/64135/3551/8737/57506/23586 10 Bovine_viral_diarrhea_virus R-HSA-112382 Formation of RNA Pol II elongation complex 22/865 61/10654 8.18294278694511e-10 3.97410647700641e-9 2.065897067620447e-9 2962/1025/79577/2963/5437/6917/5441/5434/5440/5438/5431/5435/904/4686/5433/5439/2071/5430/5432/22916/5436/25920 22 Bovine_viral_diarrhea_virus R-HSA-75955 RNA Polymerase II Transcription Elongation 22/865 61/10654 8.18294278694511e-10 3.97410647700641e-9 2.065897067620447e-9 2962/1025/79577/2963/5437/6917/5441/5434/5440/5438/5431/5435/904/4686/5433/5439/2071/5430/5432/22916/5436/25920 22 Bovine_viral_diarrhea_virus R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 20/865 51/10654 8.581119394220574e-10 4.150946246648762e-9 2.1578253447455245e-9 3646/6202/6228/6203/3921/6188/6189/6194/8894/1965/27335/6191/6217/6187/6208/6210/6231/8668/6233/6230 20 Bovine_viral_diarrhea_virus R-HSA-211981 Xenobiotics 14/865 25/10654 9.32884233149785e-10 4.477109764604677e-9 2.3273779873857054e-9 1543/1576/29785/1553/1572/1548/1577/1571/1558/1557/1562/1559/1555/1544 14 Bovine_viral_diarrhea_virus R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus 14/865 25/10654 9.32884233149785e-10 4.477109764604677e-9 2.3273779873857054e-9 7311/23385/1956/55851/51107/7316/4854/5663/4904/7314/5664/83464/6233/11060 14 Bovine_viral_diarrhea_virus R-HSA-937039 IRAK1 recruits IKK complex 11/865 15/10654 9.584403073003155e-10 4.563823182027674e-9 2.3724550369851563e-9 1147/7311/8517/7334/7316/3551/7335/3654/7189/7314/6233 11 Bovine_viral_diarrhea_virus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 11/865 15/10654 9.584403073003155e-10 4.563823182027674e-9 2.3724550369851563e-9 1147/7311/8517/7334/7316/3551/7335/3654/7189/7314/6233 11 Bovine_viral_diarrhea_virus R-HSA-1839126 FGFR2 mutant receptor activation 16/865 33/10654 9.723547700707328e-10 4.612064065043671e-9 2.3975325479524117e-9 2962/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 16 Bovine_viral_diarrhea_virus R-HSA-72649 Translation initiation complex formation 21/865 58/10654 1.8285496756715186e-9 8.639542847455742e-9 4.491174642000222e-9 3646/26986/6202/6228/6203/3921/6188/6189/6194/8894/1965/27335/6191/6217/6187/6208/6210/6231/8668/6233/6230 21 Bovine_viral_diarrhea_virus R-HSA-110320 Translesion Synthesis by POLH 12/865 19/10654 2.2510182204098857e-9 1.059456065899479e-8 5.507469899153632e-9 7311/83932/5983/5429/5985/7316/5981/55666/5111/7314/6233/7415 12 Bovine_viral_diarrhea_virus R-HSA-2142753 Arachidonic acid metabolism 21/865 59/10654 2.624781061292609e-9 1.225903491845092e-8 6.3727291748261774e-9 1543/5743/6916/5730/8644/2687/2876/2877/5740/5742/1545/9536/1558/1557/2879/80142/27306/1559/2678/10728/1544 21 Bovine_viral_diarrhea_virus R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 21/865 59/10654 2.624781061292609e-9 1.225903491845092e-8 6.3727291748261774e-9 3646/26986/6202/6228/6203/3921/6188/6189/6194/8894/1965/27335/6191/6217/6187/6208/6210/6231/8668/6233/6230 21 Bovine_viral_diarrhea_virus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 18/865 44/10654 2.6830208708356444e-9 1.2483215425758208e-8 6.489267031912648e-9 22938/1025/7311/4088/64750/7323/904/7316/9611/7027/7321/3065/9612/4087/6667/4609/7314/6233 18 Bovine_viral_diarrhea_virus R-HSA-9012852 Signaling by NOTCH3 19/865 49/10654 2.848673914327919e-9 1.3203549435611155e-8 6.863725020714059e-9 22938/7311/1387/23385/1956/2033/55851/51107/7316/4854/23462/5663/4904/6772/7314/5664/83464/6233/11060 19 Bovine_viral_diarrhea_virus R-HSA-162587 HIV Life Cycle 36/865 152/10654 3.012874716722758e-9 1.3911720756382734e-8 7.231860364701359e-9 2962/7514/1025/7311/9883/6881/2963/5437/6917/5441/5434/5440/5438/7251/5431/5435/904/79720/4686/7316/3159/5433/2547/5439/2071/5430/5901/5432/22916/4836/5436/8148/7314/7520/6233/25920 36 Bovine_viral_diarrhea_virus R-HSA-211945 Phase I - Functionalization of compounds 29/865 106/10654 3.111873160719928e-9 1.4314616539311667e-8 7.441301460788071e-9 1543/1576/29785/1553/124/6916/1572/126/130/1548/1577/5740/1571/5742/1545/1558/1557/2052/127/6256/128/218/1562/1559/125/10728/1555/3326/1544 29 Bovine_viral_diarrhea_virus R-HSA-9006936 Signaling by TGF-beta family members 28/865 102/10654 5.3573986714905925e-9 2.4551387144913656e-8 1.2762777998564848e-8 22938/7514/57154/1025/7311/5590/387/4088/7040/64750/7323/904/7316/9611/7027/5501/7321/3065/9612/9040/10273/4087/6667/4738/4609/7314/657/6233 28 Bovine_viral_diarrhea_virus R-HSA-211999 CYP2E1 reactions 9/865 11/10654 6.98230229809472e-9 3.143872679001264e-8 1.6343088405153154e-8 29785/1553/1572/1548/1571/1558/1557/1559/1555 9 Bovine_viral_diarrhea_virus R-HSA-77588 SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs 9/865 11/10654 6.98230229809472e-9 3.143872679001264e-8 1.6343088405153154e-8 6637/6635/6634/4686/7884/134353/22916/6628/6636 9 Bovine_viral_diarrhea_virus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 9/865 11/10654 6.98230229809472e-9 3.143872679001264e-8 1.6343088405153154e-8 7311/23118/6885/7316/10454/7189/7314/6233/257397 9 Bovine_viral_diarrhea_virus R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 9/865 11/10654 6.98230229809472e-9 3.143872679001264e-8 1.6343088405153154e-8 7311/23118/6885/7316/10454/7189/7314/6233/257397 9 Bovine_viral_diarrhea_virus R-HSA-167172 Transcription of the HIV genome 23/865 73/10654 6.989249352004451e-9 3.143872679001264e-8 1.6343088405153154e-8 2962/1025/6881/2963/5437/6917/5441/5434/5440/5438/5431/5435/904/4686/5433/5439/2071/5430/5432/22916/5436/8148/25920 23 Bovine_viral_diarrhea_virus R-HSA-447115 Interleukin-12 family signaling 20/865 57/10654 8.370091707044092e-9 3.7511550701789515e-8 1.9499981453717278e-8 149233/3594/2939/6888/9987/1072/3717/51561/6627/4282/552900/6175/3181/7297/3185/3593/5721/6772/9446/6647 20 Bovine_viral_diarrhea_virus R-HSA-1226099 Signaling by FGFR in disease 21/865 63/10654 1.0206287733016806e-8 4.5573130939734386e-8 2.369070836813618e-8 5295/2962/2963/5437/5441/5434/5440/5290/5438/5431/3845/5435/4686/3265/5433/5439/5430/5432/22916/5436/6772 21 Bovine_viral_diarrhea_virus R-HSA-2990846 SUMOylation 40/865 188/10654 1.1086713261011803e-8 4.932373527435543e-8 2.5640420219474093e-8 672/10155/7020/9883/7341/1387/8517/3183/9641/25950/5465/2033/23512/648/5885/8243/9126/57332/7703/1655/3065/3066/7157/5970/4792/3190/1107/9759/9612/8856/6256/7329/6045/6790/4791/5371/5111/8924/2099/4869 40 Bovine_viral_diarrhea_virus R-HSA-72702 Ribosomal scanning and start codon recognition 20/865 58/10654 1.1813008565661272e-8 5.23638452419676e-8 2.7220789115896985e-8 3646/6202/6228/6203/3921/6188/6189/6194/8894/1965/27335/6191/6217/6187/6208/6210/6231/8668/6233/6230 20 Bovine_viral_diarrhea_virus R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 14/865 29/10654 1.1915583694317198e-8 5.262716131656763e-8 2.735767118222332e-8 5437/5441/5434/5440/84944/5438/3320/5431/5435/5433/5439/5430/5432/5436 14 Bovine_viral_diarrhea_virus R-HSA-162599 Late Phase of HIV Life Cycle 33/865 139/10654 1.2888388602939615e-8 5.671821554867651e-8 2.9484362298953636e-8 2962/7514/1025/7311/9883/6881/2963/5437/6917/5441/5434/5440/5438/7251/5431/5435/904/79720/4686/7316/5433/5439/2071/5430/5901/5432/22916/4836/5436/8148/7314/6233/25920 33 Bovine_viral_diarrhea_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 39/865 182/10654 1.3744632930313265e-8 6.026873216565421e-8 3.1330060674171095e-8 672/10155/7020/9883/7341/1387/8517/3183/9641/5465/2033/23512/648/5885/8243/9126/57332/7703/1655/3065/3066/7157/5970/4792/3190/1107/9759/9612/8856/6256/7329/6045/6790/4791/5371/5111/8924/2099/4869 39 Bovine_viral_diarrhea_virus R-HSA-73893 DNA Damage Bypass 18/865 48/10654 1.3939974989742422e-8 6.090619896951977e-8 3.166144102556099e-8 7311/83932/7706/5983/5429/5985/8450/7316/5981/9978/55666/5424/9246/5111/9100/7314/6233/7415 18 Bovine_viral_diarrhea_virus R-HSA-8848021 Signaling by PTK6 19/865 54/10654 1.8769695076607212e-8 8.142440675581563e-8 4.2327613546048113e-8 202559/1017/7311/3091/2064/5921/387/1956/6421/10657/3845/5770/7316/595/3265/207/9021/7314/6233 19 Bovine_viral_diarrhea_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 19/865 54/10654 1.8769695076607212e-8 8.142440675581563e-8 4.2327613546048113e-8 202559/1017/7311/3091/2064/5921/387/1956/6421/10657/3845/5770/7316/595/3265/207/9021/7314/6233 19 Bovine_viral_diarrhea_virus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 16/865 39/10654 1.971175592503712e-8 8.520790947737678e-8 4.4294427274626154e-8 7311/83932/7706/5983/5429/5985/7316/5981/55666/5424/9246/5111/9100/7314/6233/7415 16 Bovine_viral_diarrhea_virus R-HSA-2162123 Synthesis of Prostaglandins (PG) and Thromboxanes (TX) 10/865 15/10654 2.439422659178411e-8 1.0470620498374941e-7 5.443040922258724e-8 5743/6916/5730/8644/5740/5742/9536/80142/27306/10728 10 Bovine_viral_diarrhea_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 10/865 15/10654 2.439422659178411e-8 1.0470620498374941e-7 5.443040922258724e-8 51135/7311/4615/7334/7316/7335/3654/7189/7314/6233 10 Bovine_viral_diarrhea_virus R-HSA-156580 Phase II - Conjugation of compounds 28/865 109/10654 2.642690845975811e-8 1.1303298741208821e-7 5.875899868060715e-8 2949/2944/2939/2940/7360/373156/4257/10327/2947/2937/2687/4259/2686/221357/494143/119391/4258/2938/27306/2954/2941/2946/653689/2948/2678/9446/2950/1544 28 Bovine_viral_diarrhea_virus R-HSA-674695 RNA Polymerase II Pre-transcription Events 24/865 84/10654 2.8344160740972984e-8 1.2080955224911212e-7 6.280156336424637e-8 2962/1025/79577/6881/2963/5437/6917/5441/5434/5440/5438/5431/5435/904/4686/5433/5439/2071/5430/5432/22916/5436/8148/25920 24 Bovine_viral_diarrhea_virus R-HSA-8943724 Regulation of PTEN gene transcription 20/865 61/10654 3.153380566050642e-8 1.3393626864166317e-7 6.962534754309507e-8 2475/10014/3725/1386/8841/8726/23512/648/57332/23466/6615/2146/3065/3066/5978/7157/1107/6045/5594/5595 20 Bovine_viral_diarrhea_virus R-HSA-193704 p75 NTR receptor-mediated signalling 26/865 97/10654 3.22891978017224e-8 1.3666851430659586e-7 7.104567644969623e-8 7311/4804/23385/387/8841/4615/4790/5599/55851/51107/7316/4803/7531/3551/3065/3066/5970/4792/5663/3654/7189/8878/7314/5664/83464/6233 26 Bovine_viral_diarrhea_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 11/865 19/10654 3.912895066993283e-8 1.6447652022982109e-7 8.550137315172258e-8 5295/7311/1956/5290/3320/3845/7316/3265/11140/7314/6233 11 Bovine_viral_diarrhea_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 11/865 19/10654 3.912895066993283e-8 1.6447652022982109e-7 8.550137315172258e-8 5295/7311/1956/5290/3320/3845/7316/3265/11140/7314/6233 11 Bovine_viral_diarrhea_virus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 12/865 23/10654 4.4463183403465326e-8 1.8625642807156093e-7 9.682342705330486e-8 7311/4088/64750/7323/7316/9611/7321/3065/9612/4087/7314/6233 12 Bovine_viral_diarrhea_virus R-HSA-6807505 RNA polymerase II transcribes snRNA genes 22/865 74/10654 4.8586252701252446e-8 2.0283096590009157e-7 1.0543952460762068e-7 2962/1025/79871/2963/5437/5441/5434/5440/51593/5438/5431/5435/904/4686/5433/5439/5430/5432/22916/5436/6667/51585 22 Bovine_viral_diarrhea_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 14/865 32/10654 5.7455130801218585e-8 2.390368752446603e-7 1.242607822609434e-7 7514/57154/7311/4088/7040/64750/7316/5501/9040/10273/4087/4738/7314/6233 14 Bovine_viral_diarrhea_virus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 10/865 16/10654 6.031485400153304e-8 2.5008097628526796e-7 1.3000194095568527e-7 7311/23118/6885/3656/7316/10454/7189/7314/6233/257397 10 Bovine_viral_diarrhea_virus R-HSA-167161 HIV Transcription Initiation 17/865 47/10654 6.595987735081846e-8 2.6712654648055716e-7 1.3886289968593363e-7 2962/6881/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/2071/5430/5432/5436/8148 17 Bovine_viral_diarrhea_virus R-HSA-167162 RNA Polymerase II HIV Promoter Escape 17/865 47/10654 6.595987735081846e-8 2.6712654648055716e-7 1.3886289968593363e-7 2962/6881/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/2071/5430/5432/5436/8148 17 Bovine_viral_diarrhea_virus R-HSA-73776 RNA Polymerase II Promoter Escape 17/865 47/10654 6.595987735081846e-8 2.6712654648055716e-7 1.3886289968593363e-7 2962/6881/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/2071/5430/5432/5436/8148 17 Bovine_viral_diarrhea_virus R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 17/865 47/10654 6.595987735081846e-8 2.6712654648055716e-7 1.3886289968593363e-7 2962/6881/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/2071/5430/5432/5436/8148 17 Bovine_viral_diarrhea_virus R-HSA-75953 RNA Polymerase II Transcription Initiation 17/865 47/10654 6.595987735081846e-8 2.6712654648055716e-7 1.3886289968593363e-7 2962/6881/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/2071/5430/5432/5436/8148 17 Bovine_viral_diarrhea_virus R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 17/865 47/10654 6.595987735081846e-8 2.6712654648055716e-7 1.3886289968593363e-7 2962/6881/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/2071/5430/5432/5436/8148 17 Bovine_viral_diarrhea_virus R-HSA-9020591 Interleukin-12 signaling 17/865 47/10654 6.595987735081846e-8 2.6712654648055716e-7 1.3886289968593363e-7 3594/2939/6888/9987/1072/3717/6627/4282/552900/6175/3181/7297/3185/3593/5721/9446/6647 17 Bovine_viral_diarrhea_virus R-HSA-111367 SLBP independent Processing of Histone Pre-mRNAs 8/865 10/10654 7.109255229119556e-8 2.869596729899582e-7 1.4917293997664598e-7 6637/6635/6634/4686/134353/22916/6628/6636 8 Bovine_viral_diarrhea_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 27/865 108/10654 8.639848908056184e-8 3.475899610204781e-7 1.806909516293147e-7 149233/5295/7124/5743/3091/3383/3717/598/3576/7040/3320/51561/4843/2335/595/3312/7412/7297/7157/3162/3593/207/9021/3553/6772/4609/6624 27 Bovine_viral_diarrhea_virus R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 10/865 17/10654 1.358202385688948e-7 5.446212855772459e-7 2.83115594246796e-7 7311/23118/6885/3656/7316/10454/7189/7314/6233/257397 10 Bovine_viral_diarrhea_virus R-HSA-918233 TRAF3-dependent IRF activation pathway 9/865 14/10654 2.0297345790595094e-7 8.112283448765711e-7 4.217084440358325e-7 84282/1387/7706/9641/2033/64135/29110/57506/23586 9 Bovine_viral_diarrhea_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 12/865 26/10654 2.524889395672937e-7 1.0058301220017355e-6 5.228701122102196e-7 7514/57154/7311/4088/7040/64750/7316/5501/10273/4087/7314/6233 12 Bovine_viral_diarrhea_virus R-HSA-400253 Circadian Clock 20/865 70/10654 4.0487639192968467e-7 1.6076362272387154e-6 8.357126279501807e-7 8454/6500/7311/3091/8945/1408/1387/1386/23411/8841/1374/5465/2033/7316/9611/5501/6256/7314/6233/1407 20 Bovine_viral_diarrhea_virus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 13/865 32/10654 4.928906238018148e-7 1.9444455353217223e-6 1.010799371584713e-6 22938/1025/7311/4088/904/7316/7027/3065/4087/6667/4609/7314/6233 13 Bovine_viral_diarrhea_virus R-HSA-5656169 Termination of translesion DNA synthesis 13/865 32/10654 4.928906238018148e-7 1.9444455353217223e-6 1.010799371584713e-6 7311/7706/5983/5429/5985/7316/5981/5424/9246/5111/9100/7314/6233 13 Bovine_viral_diarrhea_virus R-HSA-5423646 Aflatoxin activation and detoxification 10/865 19/10654 5.54753853876772e-7 2.181435315728339e-6 1.1339959933236564e-6 1576/1553/4257/2687/4259/1577/2686/4258/2678/1544 10 Bovine_viral_diarrhea_virus R-HSA-168325 Viral Messenger RNA Synthesis 15/865 43/10654 6.776216117386125e-7 2.656015256300221e-6 1.3807013378461493e-6 2962/9883/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 15 Bovine_viral_diarrhea_virus R-HSA-5213460 RIPK1-mediated regulated necrosis 10/865 20/10654 1.0289251329894096e-6 4.00721960739326e-6 2.0831105769619125e-6 330/7311/11035/329/841/7186/7316/8737/7314/6233 10 Bovine_viral_diarrhea_virus R-HSA-5218859 Regulated Necrosis 10/865 20/10654 1.0289251329894096e-6 4.00721960739326e-6 2.0831105769619125e-6 330/7311/11035/329/841/7186/7316/8737/7314/6233 10 Bovine_viral_diarrhea_virus R-HSA-8863795 Downregulation of ERBB2 signaling 12/865 29/10654 1.0789825113557356e-6 4.188788794084846e-6 2.1774973913380926e-6 7311/2064/8065/1956/3320/7316/10273/207/11140/208/7314/6233 12 Bovine_viral_diarrhea_virus R-HSA-1643713 Signaling by EGFR in Cancer 11/865 25/10654 1.4627393500365198e-6 5.66056910379212e-6 2.9425867626465666e-6 5295/7311/1956/5290/3320/3845/7316/3265/11140/7314/6233 11 Bovine_viral_diarrhea_virus R-HSA-5218921 VEGFR2 mediated cell proliferation 10/865 21/10654 1.821737371340235e-6 7.00535601155756e-6 3.6416599619685256e-6 5170/5921/5590/3845/5579/3265/801/5578/6714/5580 10 Bovine_viral_diarrhea_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 10/865 21/10654 1.821737371340235e-6 7.00535601155756e-6 3.6416599619685256e-6 5971/1387/4790/3845/2033/3265/5567/5970/5568/5566 10 Bovine_viral_diarrhea_virus R-HSA-9018677 Biosynthesis of DHA-derived SPMs 9/865 17/10654 1.969361772045074e-6 7.549220126172784e-6 3.924381948927954e-6 1543/1576/5743/1571/1558/2879/1559/2948/1544 9 Bovine_viral_diarrhea_virus R-HSA-2122948 Activated NOTCH1 Transmits Signal to the Nucleus 12/865 31/10654 2.5189992831660426e-6 9.625893812474626e-6 5.003918721220781e-6 409/7311/23385/408/55851/51107/7316/5663/7314/5664/83464/6233 12 Bovine_viral_diarrhea_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 16/865 53/10654 2.6208357965954267e-6 9.983746362655704e-6 5.189944570889629e-6 841/598/581/708/5599/7531/7027/8655/7157/207/10971/140735/4836/5594/208/5595 16 Bovine_viral_diarrhea_virus R-HSA-4420097 VEGFA-VEGFR2 Pathway 23/865 99/10654 3.058569515685709e-6 1.1614941556451337e-5 6.037904077530077e-6 2475/5295/5170/1432/5921/5590/387/5290/3320/3845/5579/5291/1499/3265/801/5567/207/5578/6714/208/5568/5580/5566 23 Bovine_viral_diarrhea_virus R-HSA-2979096 NOTCH2 Activation and Transmission of Signal to the Nucleus 10/865 22/10654 3.0975961709772245e-6 1.172661407584235e-5 6.09595585135106e-6 7311/23385/55851/51107/7316/5663/7314/5664/83464/6233 10 Bovine_viral_diarrhea_virus R-HSA-211897 Cytochrome P450 - arranged by substrate type 18/865 66/10654 3.2144274717798907e-6 1.213122937492163e-5 6.306290819656167e-6 1543/1576/29785/1553/6916/1572/1548/1577/5740/1571/1545/1558/1557/6256/1562/1559/1555/1544 18 Bovine_viral_diarrhea_virus R-HSA-3299685 Detoxification of Reactive Oxygen Species 13/865 37/10654 3.4457971604846396e-6 1.2964280057502394e-5 6.739343374307191e-6 2882/7295/2876/2877/7001/847/493869/257202/2878/2936/2880/2950/6647 13 Bovine_viral_diarrhea_virus R-HSA-5675482 Regulation of necroptotic cell death 9/865 18/10654 3.6553512182169697e-6 1.3668322500019896e-5 7.105332364761434e-6 330/7311/329/841/7186/7316/8737/7314/6233 9 Bovine_viral_diarrhea_virus R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 9/865 18/10654 3.6553512182169697e-6 1.3668322500019896e-5 7.105332364761434e-6 6196/1956/6197/3845/6195/3265/5578/5594/5595 9 Bovine_viral_diarrhea_virus R-HSA-1251985 Nuclear signaling by ERBB4 12/865 32/10654 3.7346644787845635e-6 1.392218960134062e-5 7.237302482627741e-6 23118/23385/348/55851/51107/9611/5663/10413/2099/6714/5664/83464 12 Bovine_viral_diarrhea_virus R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 16/865 55/10654 4.499540975198786e-6 1.6722379416973537e-5 8.692951434755038e-6 3303/7277/84617/10383/3320/1781/3312/1783/8655/1639/140735/7280/10963/10728/1778/3326 16 Bovine_viral_diarrhea_virus R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 13/865 38/10654 4.851706592825907e-6 1.7976384001990215e-5 9.34483240723467e-6 2939/6888/9987/1072/6627/4282/552900/6175/3181/3185/5721/9446/6647 13 Bovine_viral_diarrhea_virus R-HSA-4755510 SUMOylation of immune response proteins 7/865 11/10654 5.604300282464962e-6 2.0701945588862992e-5 1.0761686666806722e-5 7341/8517/9641/5970/4792/7329/4791 7 Bovine_viral_diarrhea_virus R-HSA-9018678 Biosynthesis of specialized proresolving mediators (SPMs) 9/865 19/10654 6.445888846123169e-6 2.3738787019408284e-5 1.234035644893035e-5 1543/1576/5743/1571/1558/2879/1559/2948/1544 9 Bovine_viral_diarrhea_virus R-HSA-933541 TRAF6 mediated IRF7 activation 11/865 29/10654 8.385112009903904e-6 3.078750463877367e-5 1.6004557482441823e-5 84282/1387/7706/9641/7186/2033/64135/29110/7189/57506/23586 11 Bovine_viral_diarrhea_virus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 20/865 84/10654 9.004629339914179e-6 3.296289238845461e-5 1.71354097127496e-5 9318/7311/7341/8533/8607/5983/5985/8450/7334/7316/5981/9978/10987/2071/5424/7329/5111/7314/6233/2873 20 Bovine_viral_diarrhea_virus R-HSA-194138 Signaling by VEGF 23/865 107/10654 1.2224272999880159e-5 4.461493648758657e-5 2.319260115325514e-5 2475/5295/5170/1432/5921/5590/387/5290/3320/3845/5579/5291/1499/3265/801/5567/207/5578/6714/208/5568/5580/5566 23 Bovine_viral_diarrhea_virus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 11/865 30/10654 1.227499488115325e-5 4.466632465709198e-5 2.3219314747696018e-5 7311/5983/5985/8450/7316/5981/9978/5424/5111/7314/6233 11 Bovine_viral_diarrhea_virus R-HSA-110312 Translesion synthesis by REV1 8/865 16/10654 1.3048010111009597e-5 4.719740155881513e-5 2.453506820811425e-5 7311/5983/5985/7316/5981/5111/7314/6233 8 Bovine_viral_diarrhea_virus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 8/865 16/10654 1.3048010111009597e-5 4.719740155881513e-5 2.453506820811425e-5 57154/7311/5590/387/7040/7316/7314/6233 8 Bovine_viral_diarrhea_virus R-HSA-6804757 Regulation of TP53 Degradation 12/865 36/10654 1.5269361403670193e-5 5.5069087429212915e-5 2.86270805512596e-5 2475/1017/7311/5170/11200/7316/7157/983/207/208/7314/6233 12 Bovine_viral_diarrhea_virus R-HSA-2559583 Cellular Senescence 34/865 195/10654 1.5673524159191617e-5 5.635995855473328e-5 2.929812620348814e-5 7295/1017/6196/7311/7014/1432/3725/25913/192670/3576/8726/4790/6197/5599/23512/648/5606/57332/7316/6195/3159/7027/23466/7321/2146/7157/5970/6045/6667/23112/5594/7314/6233/5595 34 Bovine_viral_diarrhea_virus R-HSA-438064 Post NMDA receptor activation events 19/865 81/10654 1.8862676297901554e-5 6.749716087907969e-5 3.508768261232761e-5 6196/5170/7277/84617/3838/10383/6197/3845/6195/3265/4137/801/5567/7280/6714/5594/5568/5595/5566 19 Bovine_viral_diarrhea_virus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 20/865 88/10654 1.888148634927496e-5 6.749716087907969e-5 3.508768261232761e-5 8454/6500/7311/7277/8945/10383/23291/3320/1781/7316/7531/8655/203068/983/1639/6790/7314/6233/1778/5566 20 Bovine_viral_diarrhea_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 12/865 37/10654 2.0944672240399277e-5 7.46536709387331e-5 3.8807918401724736e-5 2475/1017/7311/5170/11200/7316/7157/983/207/208/7314/6233 12 Bovine_viral_diarrhea_virus R-HSA-5655862 Translesion synthesis by POLK 8/865 17/10654 2.2895697523422482e-5 8.113330023561629e-5 4.217628491156774e-5 7311/5983/5985/7316/5981/5111/7314/6233 8 Bovine_viral_diarrhea_virus R-HSA-5656121 Translesion synthesis by POLI 8/865 17/10654 2.2895697523422482e-5 8.113330023561629e-5 4.217628491156774e-5 7311/5983/5985/7316/5981/5111/7314/6233 8 Bovine_viral_diarrhea_virus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 7/865 13/10654 2.5197217081885948e-5 8.87728544012109e-5 4.614762605200895e-5 7311/2064/7316/207/208/7314/6233 7 Bovine_viral_diarrhea_virus R-HSA-5357786 TNFR1-induced proapoptotic signaling 7/865 13/10654 2.5197217081885948e-5 8.87728544012109e-5 4.614762605200895e-5 7124/7128/7132/841/7186/1540/8737 7 Bovine_viral_diarrhea_virus R-HSA-912631 Regulation of signaling by CBL 9/865 22/10654 2.77587727210418e-5 9.751568860792494e-5 5.0692495610699726e-5 5295/7311/5290/5291/7316/6850/7314/6233/7525 9 Bovine_viral_diarrhea_virus R-HSA-5633007 Regulation of TP53 Activity 29/865 160/10654 3.1112363042955015e-5 1.0898267399242e-4 5.665348624276746e-5 2475/672/1017/7311/1460/5170/1432/6881/11200/5300/580/5983/5985/2033/7316/1459/3065/3066/7157/1107/1457/983/207/6790/5371/208/8148/7314/6233 29 Bovine_viral_diarrhea_virus R-HSA-9009391 Extra-nuclear estrogen signaling 18/865 77/10654 3.268001501020969e-5 1.1414595500700747e-4 5.933756307086785e-5 5295/7514/5170/5590/1956/5290/3320/3845/595/3265/801/207/2099/6714/5594/208/5595/2787 18 Bovine_viral_diarrhea_virus R-HSA-1980145 Signaling by NOTCH2 11/865 33/10654 3.466825897393917e-5 1.2005854457168138e-4 6.241115999495031e-5 7311/23385/2033/55851/51107/7316/5663/7314/5664/83464/6233 11 Bovine_viral_diarrhea_virus R-HSA-2559585 Oncogene Induced Senescence 11/865 33/10654 3.466825897393917e-5 1.2005854457168138e-4 6.241115999495031e-5 7311/192670/7316/7027/7157/6667/23112/5594/7314/6233/5595 11 Bovine_viral_diarrhea_virus R-HSA-9022692 Regulation of MECP2 expression and activity 11/865 33/10654 3.466825897393917e-5 1.2005854457168138e-4 6.241115999495031e-5 27161/8841/192670/9611/801/3065/3066/9612/4204/23112/5566 11 Bovine_viral_diarrhea_virus R-HSA-5617472 Activation of anterior HOX genes in hindbrain development during early embryogenesis 24/865 122/10654 3.7816359102881036e-5 1.3022073939664402e-4 6.76938691047707e-5 3725/22976/1387/5437/5441/5434/5440/8841/5438/8726/5431/2033/23512/5435/5433/9611/10664/7703/5439/2146/5430/5432/6256/5436 24 Bovine_viral_diarrhea_virus R-HSA-5619507 Activation of HOX genes during differentiation 24/865 122/10654 3.7816359102881036e-5 1.3022073939664402e-4 6.76938691047707e-5 3725/22976/1387/5437/5441/5434/5440/8841/5438/8726/5431/2033/23512/5435/5433/9611/10664/7703/5439/2146/5430/5432/6256/5436 24 Bovine_viral_diarrhea_virus R-HSA-350054 Notch-HLH transcription pathway 10/865 28/10654 4.005561431413702e-5 1.3754308126460006e-4 7.150031079943807e-5 10014/22938/1387/8841/4854/9611/3065/3066/9759/9612 10 Bovine_viral_diarrhea_virus R-HSA-450341 Activation of the AP-1 family of transcription factors 6/865 10/10654 4.447477468358453e-5 1.5228862454856612e-4 7.916562495422202e-5 1432/3725/1386/5599/5594/5595 6 Bovine_viral_diarrhea_virus R-HSA-3371568 Attenuation phase 7/865 14/10654 4.6865761135534366e-5 1.5897561118499473e-4 8.26417839759655e-5 3303/1387/3320/2033/3312/10728/3326 7 Bovine_viral_diarrhea_virus R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 7/865 14/10654 4.6865761135534366e-5 1.5897561118499473e-4 8.26417839759655e-5 8841/9611/801/3065/9612/4204/5566 7 Bovine_viral_diarrhea_virus R-HSA-9005895 Pervasive developmental disorders 7/865 14/10654 4.6865761135534366e-5 1.5897561118499473e-4 8.26417839759655e-5 8841/9611/801/3065/9612/4204/5566 7 Bovine_viral_diarrhea_virus R-HSA-1169408 ISG15 antiviral mechanism 17/865 72/10654 4.69493191358475e-5 1.5897561118499473e-4 8.26417839759655e-5 3839/7311/9883/3838/5610/7706/5300/9775/7334/7316/9246/3434/6772/7314/6233/5595/23586 17 Bovine_viral_diarrhea_virus R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 15/865 59/10654 5.201395435192526e-5 1.7563714779777532e-4 9.130310692479664e-5 7322/79577/7311/5591/7323/7334/7316/7319/7321/7332/8915/5111/7314/6233/7415 15 Bovine_viral_diarrhea_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 18/865 80/10654 5.627398357722832e-5 1.894971988415506e-4 9.850810733786406e-5 3839/7311/9883/3838/5610/8638/7706/5300/9775/7334/7316/9246/3434/6772/7314/6233/5595/23586 18 Bovine_viral_diarrhea_virus R-HSA-5693532 DNA Double-Strand Break Repair 29/865 166/10654 6.266223579525464e-5 2.1002858243986453e-4 1.0918112916436982e-4 672/1017/7311/6047/22976/7341/11200/25/3838/51567/580/5983/5429/5985/5599/5591/7334/7316/5981/322/2547/7157/5424/7329/5111/8924/7314/7520/6233 29 Bovine_viral_diarrhea_virus R-HSA-5260271 Diseases of Immune System 9/865 24/10654 6.288796767067313e-5 2.1002858243986453e-4 1.0918112916436982e-4 51135/1147/8517/4615/4790/3551/5970/4792/4791 9 Bovine_viral_diarrhea_virus R-HSA-5602358 Diseases associated with the TLR signaling cascade 9/865 24/10654 6.288796767067313e-5 2.1002858243986453e-4 1.0918112916436982e-4 51135/1147/8517/4615/4790/3551/5970/4792/4791 9 Bovine_viral_diarrhea_virus R-HSA-5696400 Dual Incision in GG-NER 12/865 41/10654 6.592042978965868e-5 2.1955465550162274e-4 1.1413315712791063e-4 7311/5983/5985/8450/7316/5981/9978/2071/5424/5111/7314/6233 12 Bovine_viral_diarrhea_virus R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 7/865 15/10654 8.172788250605878e-5 2.692602399321234e-4 1.399720775779442e-4 7311/81030/7316/29110/81844/7314/6233 7 Bovine_viral_diarrhea_virus R-HSA-430039 mRNA decay by 5' to 3' exoribonuclease 7/865 15/10654 8.172788250605878e-5 2.692602399321234e-4 1.399720775779442e-4 51690/1656/23658/11157/57819/27258/25804 7 Bovine_viral_diarrhea_virus R-HSA-5637810 Constitutive Signaling by EGFRvIII 7/865 15/10654 8.172788250605878e-5 2.692602399321234e-4 1.399720775779442e-4 5295/1956/5290/3320/3845/3265/11140 7 Bovine_viral_diarrhea_virus R-HSA-5637812 Signaling by EGFRvIII in Cancer 7/865 15/10654 8.172788250605878e-5 2.692602399321234e-4 1.399720775779442e-4 5295/1956/5290/3320/3845/3265/11140 7 Bovine_viral_diarrhea_virus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 12/865 42/10654 8.555236233058577e-5 2.8110061908621036e-4 1.4612717299762417e-4 10898/29894/9883/53981/10189/81608/4686/7884/8189/51692/22916/55339 12 Bovine_viral_diarrhea_virus R-HSA-9013700 NOTCH4 Activation and Transmission of Signal to the Nucleus 6/865 11/10654 9.111934396492824e-5 2.9815976130627853e-4 1.5499518700088917e-4 23385/55851/51107/5663/5664/83464 6 Bovine_viral_diarrhea_virus R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 9/865 25/10654 9.123346264745028e-5 2.9815976130627853e-4 1.5499518700088917e-4 7311/5983/5985/7316/5981/5424/5111/7314/6233 9 Bovine_viral_diarrhea_virus R-HSA-8876384 Listeria monocytogenes entry into host cells 8/865 20/10654 9.515779177650647e-5 3.101533373678112e-4 1.6122992020674613e-4 7311/999/7316/1499/4233/6714/7314/6233 8 Bovine_viral_diarrhea_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 19/865 92/10654 1.2134828974168857e-4 3.9446284052031567e-4 2.0505732048981483e-4 672/1017/7311/1460/1432/6881/11200/5300/580/5983/5985/7316/1459/7157/1457/6790/8148/7314/6233 19 Bovine_viral_diarrhea_virus R-HSA-1295596 Spry regulation of FGF signaling 7/865 16/10654 1.351455610355417e-4 4.3814478431469507e-4 2.2776491529506192e-4 7311/7316/6714/5594/7314/6233/5595 7 Bovine_viral_diarrhea_virus R-HSA-913531 Interferon Signaling 32/865 199/10654 1.3827806290218734e-4 4.47111296227497e-4 2.3242606133496243e-4 3839/7311/9883/7341/3838/3383/5610/8638/3717/7706/5300/9775/3437/7334/5770/7316/7412/3107/7297/5696/9246/9021/3434/5371/6772/3433/3659/7314/6233/5595/5580/23586 32 Bovine_viral_diarrhea_virus R-HSA-442755 Activation of NMDA receptors and postsynaptic events 19/865 93/10654 1.411372427241251e-4 4.551489388378531e-4 2.366043445277731e-4 6196/5170/7277/84617/3838/10383/6197/3845/6195/3265/4137/801/5567/7280/6714/5594/5568/5595/5566 19 Bovine_viral_diarrhea_virus R-HSA-8941326 RUNX2 regulates bone development 10/865 32/10654 1.4596984083649754e-4 4.694913878092098e-4 2.440601143829233e-4 25/8841/10432/23462/9759/10413/6714/5594/7525/5595 10 Bovine_viral_diarrhea_virus R-HSA-5696394 DNA Damage Recognition in GG-NER 11/865 38/10654 1.4787806360847314e-4 4.731321772670046e-4 2.45952740136209e-4 9318/7311/8533/8607/8450/7316/9978/10987/7314/6233/2873 11 Bovine_viral_diarrhea_virus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 11/865 38/10654 1.4787806360847314e-4 4.731321772670046e-4 2.45952740136209e-4 7020/7341/1387/2064/1956/348/2033/7329/2099/4609/4869 11 Bovine_viral_diarrhea_virus R-HSA-3371511 HSF1 activation 6/865 12/10654 1.6973244059080624e-4 5.374125846238774e-4 2.7936822757529834e-4 3320/7531/1915/10728/7415/3326 6 Bovine_viral_diarrhea_virus R-HSA-5689877 Josephin domain DUBs 6/865 12/10654 1.6973244059080624e-4 5.374125846238774e-4 2.7936822757529834e-4 7311/4287/7316/7314/6233/7415 6 Bovine_viral_diarrhea_virus R-HSA-71384 Ethanol oxidation 6/865 12/10654 1.6973244059080624e-4 5.374125846238774e-4 2.7936822757529834e-4 124/126/130/127/128/125 6 Bovine_viral_diarrhea_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 6/865 12/10654 1.6973244059080624e-4 5.374125846238774e-4 2.7936822757529834e-4 7311/9641/7316/29110/7314/6233 6 Bovine_viral_diarrhea_virus R-HSA-3899300 SUMOylation of transcription cofactors 12/865 45/10654 1.772999224271572e-4 5.599186669396493e-4 2.9106777556899005e-4 10155/7341/1387/2033/648/57332/7703/1655/9612/7329/6045/4869 12 Bovine_viral_diarrhea_virus R-HSA-187037 Signaling by NTRK1 (TRKA) 17/865 80/10654 1.8955806820377834e-4 5.970834241354155e-4 3.1038748009975403e-4 5295/6196/1432/1173/387/161/5290/4914/6197/3845/5291/6195/4803/3265/6714/5594/5595 17 Bovine_viral_diarrhea_virus R-HSA-389356 CD28 co-stimulation 10/865 33/10654 1.943618329506527e-4 6.106367896052722e-4 3.1743305327263413e-4 2475/5295/5170/3932/5290/9020/207/6714/208/7525 10 Bovine_viral_diarrhea_virus R-HSA-389357 CD28 dependent PI3K/Akt signaling 8/865 22/10654 2.0860466016735707e-4 6.520232839589956e-4 3.38947383051954e-4 2475/5295/5170/3932/5290/9020/207/208 8 Bovine_viral_diarrhea_virus R-HSA-9613829 Chaperone Mediated Autophagy 8/865 22/10654 2.0860466016735707e-4 6.520232839589956e-4 3.38947383051954e-4 7311/3320/7316/3312/1915/7314/6233/3326 8 Bovine_viral_diarrhea_virus R-HSA-9034015 Signaling by NTRK3 (TRKC) 7/865 17/10654 2.1372046549402465e-4 6.663049806578415e-4 3.463715714831144e-4 5295/5290/581/3845/3265/6714/25920 7 Bovine_viral_diarrhea_virus R-HSA-5654741 Signaling by FGFR3 11/865 40/10654 2.44437908561176e-4 7.601270676940652e-4 3.951439875237057e-4 5295/7311/5290/3845/7316/3265/6714/5594/7314/6233/5595 11 Bovine_viral_diarrhea_virus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 12/865 47/10654 2.7692527989289876e-4 8.524543338117262e-4 4.43139336777047e-4 409/8826/3717/2335/3845/408/3265/801/5245/6714/5594/5595 12 Bovine_viral_diarrhea_virus R-HSA-6802949 Signaling by RAS mutants 12/865 47/10654 2.7692527989289876e-4 8.524543338117262e-4 4.43139336777047e-4 409/8826/3717/2335/3845/408/3265/801/5245/6714/5594/5595 12 Bovine_viral_diarrhea_virus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 12/865 47/10654 2.7692527989289876e-4 8.524543338117262e-4 4.43139336777047e-4 409/8826/3717/2335/3845/408/3265/801/5245/6714/5594/5595 12 Bovine_viral_diarrhea_virus R-HSA-9649948 Signaling downstream of RAS mutants 12/865 47/10654 2.7692527989289876e-4 8.524543338117262e-4 4.43139336777047e-4 409/8826/3717/2335/3845/408/3265/801/5245/6714/5594/5595 12 Bovine_viral_diarrhea_virus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 11/865 41/10654 3.0989431744406486e-4 9.491486757897364e-4 4.934048640606375e-4 10898/29894/9883/53981/10189/81608/4686/8189/51692/22916/55339 11 Bovine_viral_diarrhea_virus R-HSA-5654743 Signaling by FGFR4 11/865 41/10654 3.0989431744406486e-4 9.491486757897364e-4 4.934048640606375e-4 5295/7311/5290/3845/7316/3265/6714/5594/7314/6233/5595 11 Bovine_viral_diarrhea_virus R-HSA-204998 Cell death signalling via NRAGE, NRIF and NADE 16/865 76/10654 3.248904594652976e-4 9.890598882078146e-4 5.141522841855744e-4 7311/4804/23385/5599/55851/51107/7316/4803/7531/5663/7189/8878/7314/5664/83464/6233 16 Bovine_viral_diarrhea_virus R-HSA-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 7/865 18/10654 3.2535932335630327e-4 9.890598882078146e-4 5.141522841855744e-4 330/329/7186/958/9020/8600/959 7 Bovine_viral_diarrhea_virus R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 7/865 18/10654 3.2535932335630327e-4 9.890598882078146e-4 5.141522841855744e-4 581/2033/7027/7157/983/6790/5111 7 Bovine_viral_diarrhea_virus R-HSA-5205647 Mitophagy 9/865 29/10654 3.32585201663707e-4 0.001008510847830992 5.242636590771187e-4 7311/1460/7316/1459/1457/6714/8878/7314/6233 9 Bovine_viral_diarrhea_virus R-HSA-8986944 Transcriptional Regulation by MECP2 14/865 62/10654 3.549705983990507e-4 0.0010737199986313717 5.581619439368644e-4 27161/8841/192670/5770/9611/801/3065/3066/4233/9612/4204/3654/23112/5566 14 Bovine_viral_diarrhea_virus R-HSA-5693606 DNA Double Strand Break Response 16/865 77/10654 3.7982318974904216e-4 0.0011460506641190157 5.957622726131407e-4 672/7311/7341/11200/25/3838/580/5599/7334/7316/322/7157/7329/8924/7314/6233 16 Bovine_viral_diarrhea_virus R-HSA-3371571 HSF1-dependent transactivation 8/865 24/10654 4.144779462040908e-4 0.0012413970919478788 6.453271010341722e-4 2475/3303/1387/3320/2033/3312/10728/3326 8 Bovine_viral_diarrhea_virus R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 8/865 24/10654 4.144779462040908e-4 0.0012413970919478788 6.453271010341722e-4 1432/5590/5300/5579/5578/5594/5595/5580 8 Bovine_viral_diarrhea_virus R-HSA-8940973 RUNX2 regulates osteoblast differentiation 8/865 24/10654 4.144779462040908e-4 0.0012413970919478788 6.453271010341722e-4 25/8841/23462/10413/6714/5594/7525/5595 8 Bovine_viral_diarrhea_virus R-HSA-2559580 Oxidative Stress Induced Senescence 22/865 125/10654 4.191187462977213e-4 0.0012522199797473585 6.509532643736538e-4 7295/7311/1432/3725/192670/8726/5599/23512/648/5606/57332/7316/7027/23466/2146/7157/6045/23112/5594/7314/6233/5595 22 Bovine_viral_diarrhea_virus R-HSA-166520 Signaling by NTRKs 19/865 101/10654 4.3098636439837466e-4 0.0012845290420577474 6.677487874606141e-4 5295/6196/1432/1173/387/161/5290/4914/581/6197/3845/5291/6195/4803/3265/6714/5594/5595/25920 19 Bovine_viral_diarrhea_virus R-HSA-114452 Activation of BH3-only proteins 9/865 30/10654 4.412864514486308e-4 0.0013024895504016487 6.770853670755085e-4 5599/7531/7027/8655/7157/207/10971/140735/208 9 Bovine_viral_diarrhea_virus R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 9/865 30/10654 4.412864514486308e-4 0.0013024895504016487 6.770853670755085e-4 6196/5170/6197/3845/6195/3265/801/5594/5595 9 Bovine_viral_diarrhea_virus R-HSA-6804758 Regulation of TP53 Activity through Acetylation 9/865 30/10654 4.412864514486308e-4 0.0013024895504016487 6.770853670755085e-4 5300/2033/3065/3066/7157/1107/207/5371/208 9 Bovine_viral_diarrhea_virus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 9/865 30/10654 4.412864514486308e-4 0.0013024895504016487 6.770853670755085e-4 7322/7311/7316/7319/7321/7332/997/7314/6233 9 Bovine_viral_diarrhea_virus R-HSA-8978868 Fatty acid metabolism 28/865 177/10654 4.653345507799179e-4 0.0013701517328519805 7.122588343999761e-4 1543/5538/5743/11332/6916/5730/8644/2687/2876/1374/2877/5740/6576/5742/1545/9536/1558/1557/2879/80142/27306/1892/6256/1559/2678/10728/1666/1544 28 Bovine_viral_diarrhea_virus R-HSA-6802957 Oncogenic MAPK signaling 15/865 71/10654 4.756191133043357e-4 0.0013970595159469522 7.262465598204442e-4 4000/409/56829/8826/3717/9444/2335/3845/408/3265/801/5245/6714/5594/5595 15 Bovine_viral_diarrhea_virus R-HSA-174490 Membrane binding and targetting of GAG proteins 6/865 14/10654 4.786852854456399e-4 0.0013977930236748148 7.266278660267161e-4 7311/7251/79720/7316/7314/6233 6 Bovine_viral_diarrhea_virus R-HSA-174495 Synthesis And Processing Of GAG, GAGPOL Polyproteins 6/865 14/10654 4.786852854456399e-4 0.0013977930236748148 7.266278660267161e-4 7311/7251/79720/7316/7314/6233 6 Bovine_viral_diarrhea_virus R-HSA-6804760 Regulation of TP53 Activity through Methylation 7/865 19/10654 4.7930884651031384e-4 0.0013977930236748148 7.266278660267161e-4 7311/11200/2033/7316/7157/7314/6233 7 Bovine_viral_diarrhea_virus R-HSA-8852135 Protein ubiquitination 16/865 79/10654 5.140200399399812e-4 0.0014954425505652438 7.773899360479055e-4 7322/79577/7311/5591/7323/7334/7316/7319/7321/7332/997/8915/5111/7314/6233/7415 16 Bovine_viral_diarrhea_virus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 8/865 25/10654 5.6659299728957e-4 0.0016444687230856806 8.548596099456672e-4 2475/1147/5170/2932/2931/6199/207/208 8 Bovine_viral_diarrhea_virus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 9/865 31/10654 5.775722804334961e-4 0.0016723529925140898 8.693549514213395e-4 6196/1432/3725/1386/6197/5599/6195/5594/5595 9 Bovine_viral_diarrhea_virus R-HSA-9614085 FOXO-mediated transcription 14/865 65/10654 5.925283905918665e-4 0.0017115926732973582 8.897532829541125e-4 7295/1387/4287/23411/4088/2033/847/57060/3065/3066/207/4087/10971/208 14 Bovine_viral_diarrhea_virus R-HSA-69231 Cyclin D associated events in G1 11/865 44/10654 6.006847411248035e-4 0.0017269686307338102 8.977463112143291e-4 8454/6500/7311/25/3717/7316/595/7027/6714/7314/6233 11 Bovine_viral_diarrhea_virus R-HSA-69236 G1 Phase 11/865 44/10654 6.006847411248035e-4 0.0017269686307338102 8.977463112143291e-4 8454/6500/7311/25/3717/7316/595/7027/6714/7314/6233 11 Bovine_viral_diarrhea_virus R-HSA-622312 Inflammasomes 7/865 20/10654 6.861594144439026e-4 0.0019680666498990995 0.001023078557263726 7295/351/598/4790/5970/4791/3326 7 Bovine_viral_diarrhea_virus R-HSA-3371556 Cellular response to heat stress 17/865 89/10654 7.084443909245292e-4 0.0020272152876455425 0.0010538263487436784 2475/3303/9883/2932/1387/23411/3309/3320/2033/3312/7531/1915/5594/10728/7415/5595/3326 17 Bovine_viral_diarrhea_virus R-HSA-844456 The NLRP3 inflammasome 6/865 15/10654 7.433235540720282e-4 0.0021220407784866566 0.0011031203736012844 7295/351/4790/5970/4791/3326 6 Bovine_viral_diarrhea_virus R-HSA-2871796 FCERI mediated MAPK activation 9/865 32/10654 7.464601915801454e-4 0.002126016293308872 0.0011051870027822125 3725/3845/5599/3265/3937/6850/5594/5595/4214 9 Bovine_viral_diarrhea_virus R-HSA-6802952 Signaling by BRAF and RAF fusions 14/865 67/10654 8.166099387907137e-4 0.0023203904787549652 0.0012062303598380805 4000/409/56829/8826/3717/9444/2335/3845/408/3265/801/6714/5594/5595 14 Bovine_viral_diarrhea_virus R-HSA-5693565 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 15/865 76/10654 0.0010085121311611126 0.0028590146229892934 0.0014862284038163766 672/7311/7341/11200/25/580/5599/7334/7316/322/7157/7329/8924/7314/6233 15 Bovine_viral_diarrhea_virus R-HSA-2514853 Condensation of Prometaphase Chromosomes 5/865 11/10654 0.0010640021199989046 0.003009323861435417 0.0015643650659160839 1460/1459/1457/983/10592 5 Bovine_viral_diarrhea_virus R-HSA-437239 Recycling pathway of L1 11/865 47/10654 0.0010898607763186092 0.0030753247368805197 0.0015986749204283696 6196/7277/1173/84617/10383/161/6197/6195/7280/6714/5594 11 Bovine_viral_diarrhea_virus R-HSA-175474 Assembly Of The HIV Virion 6/865 16/10654 0.0011082303498939213 0.0031199371744126793 0.0016218662225261718 7311/7251/79720/7316/7314/6233 6 Bovine_viral_diarrhea_virus R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 7/865 22/10654 0.0013074506895614406 0.0036638675645411407 0.0019046226621076523 4000/3725/351/7001/7531/823/2801 7 Bovine_viral_diarrhea_virus R-HSA-8863678 Neurodegenerative Diseases 7/865 22/10654 0.0013074506895614406 0.0036638675645411407 0.0019046226621076523 4000/3725/351/7001/7531/823/2801 7 Bovine_viral_diarrhea_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 11/865 48/10654 0.0013120856682513693 0.003668423003666099 0.0019069907587815655 5295/7311/3717/5290/5291/7316/6850/7314/6233/7525/5566 11 Bovine_viral_diarrhea_virus R-HSA-6798695 Neutrophil degranulation 58/865 480/10654 0.0013227238366369841 0.0036897033337768502 0.0019180531125026245 10450/5718/3303/1460/5689/1432/8826/5701/23385/4257/10383/387/161/5036/5683/55832/5708/3320/5686/4790/5713/3615/847/4282/3608/2495/1938/10213/5709/3312/80142/1509/5695/2444/1915/2547/3107/5707/5315/8655/5702/203068/5663/823/5719/10075/5594/1654/23406/7520/7415/2950/1778/5717/9861/3326/3417/5580 58 Bovine_viral_diarrhea_virus R-HSA-5628897 TP53 Regulates Metabolic Genes 16/865 86/10654 0.0013485417984804911 0.0037531334528486727 0.001951026586602393 2475/9377/7295/27161/4513/192670/2877/7001/7531/2539/7157/207/10971/23112/2936/208 16 Bovine_viral_diarrhea_virus R-HSA-114604 GPVI-mediated activation cascade 9/865 35/10654 0.0015068507218775607 0.004174661431747151 0.0021701534319863436 5295/5170/3932/5590/387/5290/5291/3937/6850 9 Bovine_viral_diarrhea_virus R-HSA-8953750 Transcriptional Regulation by E2F6 9/865 35/10654 0.0015068507218775607 0.004174661431747151 0.0021701534319863436 672/8726/10138/23512/648/7027/7703/2146/6045 9 Bovine_viral_diarrhea_virus R-HSA-68877 Mitotic Prometaphase 29/865 200/10654 0.0015442252955329022 0.004268504841847183 0.002218936932595315 7514/9184/1460/7277/84617/10383/54908/3320/5885/8243/1781/9126/10426/7531/5501/1459/1783/8655/991/203068/1457/983/1639/140735/10592/7280/1063/1778/5566 29 Bovine_viral_diarrhea_virus R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 10/865 42/10654 0.0015819366909180768 0.004362852548029718 0.0022679825861697603 7514/7311/8945/7316/1499/3065/207/208/7314/6233 10 Bovine_viral_diarrhea_virus R-HSA-4655427 SUMOylation of DNA methylation proteins 6/865 17/10654 0.0015961448322938674 0.004382208447221226 0.0022780445449049514 7341/648/57332/7703/7329/6045 6 Bovine_viral_diarrhea_virus R-HSA-8934593 Regulation of RUNX1 Expression and Activity 6/865 17/10654 0.0015961448322938674 0.004382208447221226 0.0022780445449049514 27161/192670/595/5371/23112/6714 6 Bovine_viral_diarrhea_virus R-HSA-186763 Downstream signal transduction 8/865 29/10654 0.0016802523883204408 0.0046027587895789155 0.0023926952992759445 5295/5921/5290/3845/5291/3265/6772/6714 8 Bovine_viral_diarrhea_virus R-HSA-174403 Glutathione synthesis and recycling 5/865 12/10654 0.001702766176718972 0.004653973025606338 0.0024193184762445626 2937/2687/2686/494143/2678 5 Bovine_viral_diarrhea_virus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 7/865 23/10654 0.0017493998033164017 0.004770734586672693 0.0024800157343611772 7311/7316/7321/991/983/7314/6233 7 Bunyavirus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 228/4506 244/10654 2.1090962188560552e-66 2.940080129085341e-63 1.3875633018789838e-63 8449/23165/6633/8683/6431/84271/55696/4904/51639/51585/9128/199746/23450/348995/57122/5431/9092/23511/81608/5435/6625/5433/51645/3190/1477/9416/65109/56339/22826/23279/22938/988/23020/23225/6631/3181/5439/1660/9410/6638/57721/9877/9972/8021/3312/10907/10291/55746/26121/10262/7919/53981/6432/10084/8563/6430/51340/56001/6627/6936/83443/11051/80145/9129/9879/8106/51690/27238/55749/5438/85313/10762/54883/22794/9785/11338/1655/9343/29107/3185/4116/6626/11157/285755/1478/24144/79902/9883/51213/10236/10250/4670/26097/51362/10465/55660/25949/23283/2521/1977/3191/10285/6636/23524/10914/57187/6396/129401/79228/8175/2733/84950/3188/84324/56259/5725/1994/10450/7536/4928/2963/6635/5434/5903/220988/6632/10283/55706/7175/24148/7884/23350/5436/10523/6428/27258/10212/6637/55110/5093/84321/6429/57819/10181/4927/2962/10898/10569/23658/6434/9295/84844/10482/51692/10421/11193/8086/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/81929/5440/51691/10946/9631/27339/5430/79869/85437/11325/57703/3184/25804/29894/9589/11017/51503/3178/79023/5441/23636/3183/10594/4686/8189/23398/10713/53371/10978/5546/7307/10772/9688/9984/5437/6629/10189/10949/51729/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/84248/6427/5356/84991/8480/10992/55339/6628 228 Bunyavirus R-HSA-72163 mRNA Splicing - Major Pathway 177/4506 183/10654 1.865888227885172e-58 1.300524094835965e-55 6.137790223306488e-56 8449/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/5431/9092/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/22938/988/23020/6631/3181/5439/1660/9410/6638/3312/10907/10291/26121/10262/53981/6432/10084/6430/51340/6627/6936/83443/11051/9129/9879/8106/51690/27238/55749/5438/85313/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/10236/10250/4670/51362/10465/55660/25949/23283/2521/3191/10285/6636/23524/10914/8175/84950/3188/56259/5725/1994/10450/7536/2963/6635/5434/220988/6632/10283/24148/23350/5436/10523/6428/27258/6637/55110/5093/6429/57819/10181/2962/10898/10569/23658/6434/9295/84844/51692/10421/11193/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/51691/10946/27339/5430/79869/11325/57703/3184/25804/29894/11017/51503/3178/5441/3183/10594/4686/8189/23398/10713/10978/5546/7307/10772/5437/6629/10189/10949/51729/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/84991/10992/55339/6628 177 Bunyavirus R-HSA-453274 Mitotic G2-G2/M phases 188/4506 198/10654 5.677232393490858e-58 2.638020652175419e-55 1.2450071038357147e-55 114791/10844/8454/5689/440145/5682/7531/11190/203068/54801/51807/63943/347688/51400/79441/143471/10381/5705/5116/7278/5048/5709/9978/1869/5695/8655/6790/9702/5711/5928/7846/7840/113457/5683/5699/11064/5702/5520/81027/8900/5518/55835/29922/23332/7465/93323/5696/5691/7314/5515/5718/8945/79861/4659/5700/122706/5707/1454/23198/993/890/983/9861/79959/5519/5698/5692/5713/80097/10376/5710/10540/7157/85378/5719/6233/7514/54930/54820/1453/27229/9793/4218/5500/84617/2305/11258/22981/8636/51512/7532/84962/55125/10382/121441/7277/5706/9133/9814/653784/23354/728642/891/9738/4331/1639/5714/55722/4957/5566/5688/5687/7283/347733/5708/22919/984/10426/22994/79866/1069/5577/5704/3326/55957/7311/10133/10383/5347/84790/80184/5694/22897/5108/4660/7280/10806/1778/5516/115106/1017/22822/22995/55559/5684/994/5720/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/112714/1781/7316/10213/80321/1026/10121/1871/5715/84131/9088/5701/23291/5685/3320/5686/2033/995/10733/4751/27175/80254/5716/23194/9662/55142/1022/8481/5693/5721/55755 188 Bunyavirus R-HSA-69275 G2/M Transition 186/4506 196/10654 3.0004013006070907e-57 1.0456398532615712e-54 4.934870560209031e-55 114791/10844/8454/5689/440145/5682/7531/11190/203068/54801/51807/63943/347688/51400/79441/143471/10381/5705/5116/7278/5048/5709/9978/5695/8655/6790/9702/5711/5928/7846/7840/113457/5683/5699/11064/5702/5520/81027/8900/5518/55835/29922/23332/7465/93323/5696/5691/7314/5515/5718/8945/79861/4659/5700/122706/5707/1454/23198/993/890/983/9861/79959/5519/5698/5692/5713/80097/10376/5710/10540/7157/85378/5719/6233/7514/54930/54820/1453/27229/9793/4218/5500/84617/2305/11258/22981/8636/51512/7532/84962/55125/10382/121441/7277/5706/9133/9814/653784/23354/728642/891/9738/4331/1639/5714/55722/4957/5566/5688/5687/7283/347733/5708/22919/984/10426/22994/79866/1069/5577/5704/3326/55957/7311/10133/10383/5347/84790/80184/5694/22897/5108/4660/7280/10806/1778/5516/115106/1017/22822/22995/55559/5684/994/5720/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/112714/1781/7316/10213/80321/1026/10121/5715/84131/9088/5701/23291/5685/3320/5686/2033/995/10733/4751/27175/80254/5716/23194/9662/55142/1022/8481/5693/5721/55755 186 Bunyavirus R-HSA-72172 mRNA Splicing 178/4506 191/10654 1.8790256543325302e-51 5.238723524279095e-49 2.472402176753329e-49 8449/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/5431/9092/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/22938/988/23020/6631/3181/5439/1660/9410/6638/3312/10907/10291/26121/10262/53981/6432/10084/6430/51340/6627/6936/83443/11051/9129/9879/8106/51690/27238/55749/5438/85313/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/10236/10250/4670/51362/10465/55660/25949/23283/2521/3191/10285/6636/23524/10914/8175/84950/3188/56259/5725/1994/10450/7536/2963/6635/5434/220988/6632/10283/24148/23350/5436/10523/6428/27258/6637/55110/5093/6429/57819/10181/2962/10898/10569/23658/6434/9295/84844/51692/10421/11193/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/51691/10946/27339/5430/79869/85437/11325/57703/3184/25804/29894/11017/51503/3178/5441/3183/10594/4686/8189/23398/10713/10978/5546/7307/10772/5437/6629/10189/10949/51729/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/84991/10992/55339/6628 178 Bunyavirus R-HSA-199977 ER to Golgi Anterograde Transport 149/4506 154/10654 2.3397086303170856e-49 5.435923051103362e-47 2.5654699893827697e-47 6811/23256/374/6711/11014/126003/10960/2153/51807/286/10484/7039/347688/5861/10381/7278/1780/9570/90411/8655/84516/832/3998/55738/7846/113457/51226/9382/375056/9632/3630/81027/6709/79090/10652/54732/51272/51164/58485/1294/79861/9117/10342/2801/377/10466/22872/1315/81562/8615/11316/91949/8729/254263/23423/10376/1314/10540/51332/83696/51128/27095/6399/7109/378/6396/26286/1453/26958/10175/140735/10959/2348/84364/22820/84617/22796/11258/6712/2890/1783/10382/10802/93661/55860/2157/830/7277/10671/9554/966/11196/1639/149111/10282/6710/8775/81876/11015/347733/51143/79748/51693/5537/9871/10383/84790/10945/1075/7280/829/1778/9919/10113/51399/11070/25839/55291/51014/122553/26984/83548/63908/112714/1604/1781/57731/1522/10121/2804/9527/57511/22870/5265/8774/10972/381/6708/4905/89866/9276/287/375/84342/64689/288/10427/22818/372 149 Bunyavirus R-HSA-5663205 Infectious disease 300/4506 383/10654 1.4156504778127497e-48 2.8191668086728186e-46 1.3304985693728853e-46 3839/6804/6158/23165/5689/51652/6138/2237/6227/7852/6206/6234/6191/162/6128/5682/6132/6129/27243/6874/6176/1174/811/6224/6146/348995/6154/143471/6202/57122/5705/55048/3981/6169/5431/23511/5435/5709/6175/9978/5433/6218/5695/292/6173/23279/5605/6167/5711/23327/116832/112755/29082/8732/23225/5683/2534/6156/5699/6143/5439/5702/6456/3836/6139/30011/2885/163/9972/3921/8021/7040/1794/11198/904/51497/5062/55746/6208/5696/6170/5691/7296/7314/5879/5718/3303/8945/6203/51606/1839/161/5606/6147/25978/5700/122706/5707/6222/2060/7518/8106/23198/84168/9636/10015/5438/6134/3978/10762/79720/6155/1500/4836/6714/6231/9861/79902/6142/11168/9883/23521/51510/999/5698/9146/5692/5713/5710/6207/5478/5719/6233/6844/7514/1025/3932/1213/5610/1211/6188/6396/129401/1175/6829/801/8907/200916/6122/2957/805/6230/60489/1173/4928/2963/3838/5434/5903/6857/6194/55706/7175/6166/1938/5436/6136/6878/3841/6125/4869/821/5706/6232/160/6160/6616/293/5611/920/4233/4331/5714/6193/6210/4927/6229/8148/6205/2962/10898/3840/5688/5687/5708/128866/140801/6235/6181/5901/8086/5704/3326/7311/6223/25873/6880/6908/7251/5694/3304/2547/9045/2961/6187/6416/5432/6168/22916/6157/6137/6144/3837/6917/81929/5440/164/5684/9349/8065/4736/2926/5720/79872/51121/9631/5604/1499/3159/6159/6217/5430/6152/5690/7520/5717/9491/6500/6749/51065/6141/79023/6123/5441/23636/10197/6164/4686/7316/10213/6872/53371/3055/6209/9688/11224/6165/8731/6130/6879/9150/5715/9525/6204/5701/2958/867/6228/5437/5685/3320/8815/5686/6124/5609/5716/9844/6189/6135/6201/375/6161/1022/5693/10254/5721/8178/8480/6133/291 300 Bunyavirus R-HSA-168254 Influenza Infection 148/4506 155/10654 1.0714067424258617e-46 1.8669262486770642e-44 8.810910710738996e-45 3839/6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/116832/23225/6156/6143/5439/3836/6139/9972/3921/8021/7040/55746/6208/6170/3303/6203/6147/6222/8106/9636/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/7514/1213/5610/1211/6188/6396/129401/200916/6122/6230/4928/2963/3838/5434/5903/6194/55706/7175/6166/5436/6136/3841/6125/821/6232/6160/293/5611/6193/6210/4927/6229/6205/2962/10898/3840/140801/6235/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/81929/5440/9349/4736/2926/51121/9631/6159/6217/5430/6152/51065/6141/79023/6123/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 148 Bunyavirus R-HSA-168255 Influenza Life Cycle 138/4506 144/10654 3.5832217792183687e-44 5.5500124002560065e-42 2.619314166095299e-42 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/116832/23225/6156/6143/5439/3836/6139/9972/3921/8021/55746/6208/6170/3303/6203/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/7514/1213/1211/6188/6396/129401/200916/6122/6230/4928/2963/5434/5903/6194/55706/7175/6166/5436/6136/6125/821/6232/6160/5611/6193/6210/4927/6229/6205/2962/140801/6235/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/81929/5440/9349/4736/2926/51121/9631/6159/6217/5430/6152/51065/6141/79023/6123/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 138 Bunyavirus R-HSA-68877 Mitotic Prometaphase 177/4506 200/10654 4.148591657637346e-43 5.78313677074646e-41 2.729336616866675e-41 114791/10844/55839/11130/440145/6249/9735/7531/1459/11190/203068/5526/54801/51807/9212/347688/1460/147841/348995/79441/10381/57122/5116/7278/1780/23122/5048/8655/1457/23279/9702/2491/7846/7840/113457/1060/11064/81027/11004/9184/5518/55835/29922/23332/10726/81930/55746/93323/5515/79682/10403/79861/64151/25936/55869/1454/64105/332/10051/5528/983/79902/3796/79959/5519/81565/80097/91687/11243/10376/23397/10540/85378/83540/7514/54930/54820/6396/1453/27229/64946/9793/140735/84617/4928/5903/11258/22981/8636/80776/1783/401541/7532/55125/10382/79172/121441/7277/9133/79980/6232/9814/653784/5885/23354/891/5501/9738/1639/55722/4957/5566/9183/1062/699/7283/347733/22919/8243/10426/5529/22994/51143/1069/5577/10383/5347/84790/84643/80184/22897/5108/10592/7280/10806/1778/5516/115106/4926/22995/55559/81929/54908/55143/5525/10142/1058/991/79019/80152/1063/95681/23421/55920/79023/10735/112714/1781/80321/4085/55166/10121/84131/3320/79003/9126/9918/10733/4751/5527/27175/80254/701/9662/55142/8481/55755 177 Bunyavirus R-HSA-2555396 Mitotic Metaphase and Anaphase 178/4506 202/10654 9.603304672319044e-43 1.217000610292068e-40 5.743603272918089e-41 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/147841/348995/143471/10381/57122/5705/7278/1780/23122/5048/5709/5695/8655/23279/5711/2491/7846/113457/5683/1060/5699/5702/5520/81027/51529/4001/29945/11004/51434/9184/5518/29882/23332/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/7444/5698/5692/5713/91687/119504/11243/10376/5710/7324/2010/83540/5719/64682/6233/7514/54820/6396/64946/9793/140735/84617/4928/26271/5903/246184/80776/1783/401541/10382/79172/7277/5706/79980/6232/8881/5885/5501/5714/9183/5688/1062/699/5687/347733/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/81929/5684/5720/54908/55143/5525/1058/991/79019/80152/5690/1063/5717/9491/23421/55920/79023/10735/10197/7443/112714/23141/1781/7316/10213/4085/55166/5715/5701/5685/8815/5686/79003/9126/9232/5527/9700/5716/701/5693/5721 178 Bunyavirus R-HSA-68882 Mitotic Anaphase 177/4506 201/10654 2.0445874337070494e-42 2.3751290688230227e-40 1.1209360930411455e-40 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/147841/348995/143471/10381/57122/5705/7278/1780/23122/5048/5709/5695/8655/23279/5711/2491/7846/113457/5683/1060/5699/5702/5520/81027/51529/4001/29945/11004/51434/9184/5518/29882/23332/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/7444/5698/5692/5713/91687/119504/11243/10376/5710/7324/2010/83540/5719/64682/6233/7514/54820/6396/64946/9793/140735/84617/4928/5903/246184/80776/1783/401541/10382/79172/7277/5706/79980/6232/8881/5885/5501/5714/9183/5688/1062/699/5687/347733/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/81929/5684/5720/54908/55143/5525/1058/991/79019/80152/5690/1063/5717/9491/23421/55920/79023/10735/10197/7443/112714/23141/1781/7316/10213/4085/55166/5715/5701/5685/8815/5686/79003/9126/9232/5527/9700/5716/701/5693/5721 177 Bunyavirus R-HSA-2467813 Separation of Sister Chromatids 168/4506 190/10654 7.707927864285051e-41 8.265270340625662e-39 3.9007732106705726e-39 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/147841/348995/143471/10381/57122/5705/7278/1780/23122/5048/5709/5695/8655/23279/5711/2491/7846/113457/5683/1060/5699/5702/81027/51529/29945/11004/51434/9184/5518/29882/23332/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/5698/5692/5713/91687/119504/11243/10376/5710/7324/83540/5719/64682/6233/7514/54820/6396/64946/9793/140735/84617/4928/5903/246184/80776/1783/401541/10382/79172/7277/5706/79980/6232/8881/5885/5501/5714/9183/5688/1062/699/5687/347733/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7280/1778/5516/81929/5684/5720/54908/55143/5525/1058/991/79019/80152/5690/1063/5717/9491/23421/55920/79023/10735/10197/112714/1781/7316/10213/4085/55166/5715/5701/5685/5686/79003/9126/9232/5527/9700/5716/701/5693/5721 168 Bunyavirus R-HSA-168273 Influenza Viral RNA Transcription and Replication 128/4506 134/10654 1.494021092192192e-40 1.4876181446542254e-38 7.020775809173836e-39 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/116832/23225/6156/6143/5439/6139/9972/3921/8021/55746/6208/6170/6203/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/6188/6396/129401/200916/6122/6230/4928/2963/5434/5903/6194/55706/7175/6166/5436/6136/6125/6232/6160/5611/6193/6210/4927/6229/6205/2962/140801/6235/6181/8086/7311/6223/25873/9045/6187/5432/6168/6157/6137/6144/81929/5440/9349/4736/2926/51121/9631/6159/6217/5430/6152/51065/6141/79023/6123/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 128 Bunyavirus R-HSA-8856688 Golgi-to-ER retrograde transport 127/4506 133/10654 3.4297484480097844e-40 3.18737955768376e-38 1.504275635092011e-38 11014/64837/11127/51807/53407/347688/3798/5861/10381/7278/1780/5048/8655/84516/832/285643/55738/10112/636/64147/7846/113457/51226/81027/11004/10749/81930/54732/51164/60561/113220/79861/3797/29127/55605/23299/377/1315/3796/5870/124602/11316/55614/89953/56992/8729/23423/10376/1314/10540/3835/147700/3833/378/9493/26286/26958/140735/10959/3831/84364/22820/84617/11258/1783/55850/9585/10382/93661/55860/830/3832/7277/10671/9554/23303/1639/8775/26153/81876/9183/1062/11015/146909/347733/662/90990/51143/23046/10383/24137/84790/84643/10945/5049/51594/22920/7280/829/1778/55582/5321/9371/51014/23095/5050/63908/112714/1781/22930/25782/10121/6836/547/51560/8774/10972/381/4905/3834/9276/55083/3799/375/221458/22818/372 127 Bunyavirus R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic 175/4506 202/10654 8.71153091266706e-40 7.589921307661176e-38 3.5820439608006006e-38 6811/400/11014/64837/60592/11311/8674/11127/51807/53407/347688/3798/5861/10381/7278/1780/5048/9570/8655/84516/832/285643/55738/10112/636/64147/7846/113457/3482/51226/9382/81027/11004/10228/10749/6293/8675/2800/339122/81930/10652/54732/51272/7110/51164/60561/113220/79861/3797/10618/9321/29127/55275/55605/23299/51209/377/10466/9827/1315/22836/3796/5870/79571/124602/11316/55614/89953/56992/91949/8729/4074/23423/10376/2803/1314/10540/3835/147700/3833/8677/10139/378/9493/26286/26958/140735/10959/3831/84364/22820/51542/84617/22796/11258/1783/27333/55850/9585/10382/93661/55860/830/3832/7277/10671/9554/23303/1639/8775/26153/81876/9183/1062/4124/11015/146909/347733/662/90990/10244/51143/9648/23046/10383/24137/84790/84643/10945/5049/90196/57589/51594/22920/7280/829/1778/55582/5321/9371/25839/51014/23095/5050/83548/63908/112714/1781/22930/738/25782/10121/9367/10226/9341/6836/9342/9527/57511/547/51560/8774/143187/10972/381/4905/3834/9276/55083/3799/375/84342/221458/22818/372 175 Bunyavirus R-HSA-69306 DNA Replication 122/4506 127/10654 1.7333433884445088e-39 1.4213415785244972e-37 6.707985249398255e-38 8454/5689/2237/9134/11065/5682/7321/8697/5982/143471/5705/5709/5422/9978/1869/4174/5695/84515/4998/5711/10926/5683/990/5699/5702/8900/51529/29945/51434/55388/84296/6117/29882/5001/5558/5696/5691/7314/996/5718/6118/23594/5700/122706/5707/64785/23198/898/3978/5557/890/51433/9861/6502/5698/5692/5985/5713/119504/4175/5710/5984/7324/5719/64682/6233/23649/5424/4999/4172/5000/8318/246184/54107/4173/5706/8881/5425/5714/5111/51053/6119/5688/5687/5427/5708/81620/10393/5704/29935/51343/23595/7311/25906/51659/5983/5694/4176/56655/1017/5684/5720/8317/9837/5690/5717/9491/6500/10197/7316/10213/5426/4171/1871/5715/5701/5685/5686/5716/5981/5693/5721 122 Bunyavirus R-HSA-68886 M Phase 293/4506 395/10654 3.4836761740645363e-39 2.6979136592477576e-37 1.2732734554329448e-37 114791/10844/23165/5689/55839/11130/11065/440145/6249/5579/5682/9735/7531/1459/11190/7321/91754/203068/5526/54801/51807/8697/5578/9212/347688/5861/5925/1460/147841/348995/79441/143471/10381/57122/5705/5116/7278/1780/23122/23511/5048/5709/5695/8655/1457/23279/9702/5711/2491/10112/7846/23225/7840/113457/5683/1060/5699/11064/5702/5520/81027/51529/4001/29945/11004/51434/9184/9972/5518/55844/55835/29922/8021/29882/23332/10726/81930/55746/93323/5696/5691/7314/996/5515/5718/79682/10403/79861/64151/25936/55869/5700/122706/5707/1454/2801/5594/23198/64105/332/10762/10051/5528/983/51433/9861/79902/3796/8615/79959/5519/9883/81565/7444/5698/5692/5713/80097/91687/119504/11243/10376/23397/5710/10540/85378/7324/2010/83540/5719/64682/6233/7514/54930/54820/9493/6396/129401/1453/27229/64946/9793/140735/84617/4928/26271/5903/55706/7175/11258/22981/246184/8636/80776/1783/401541/7532/55125/10382/79172/121441/7277/5706/9133/79980/25836/6232/8881/9814/653784/5885/23354/891/5501/9738/1639/5714/55722/4957/4927/5566/81876/9183/5688/1062/699/5687/7283/347733/5708/22919/8243/10426/5529/22994/51143/1069/8086/10393/79648/5577/5704/7311/25906/10383/5347/54892/84790/84643/80184/5694/22897/6418/5108/7112/10592/7280/10806/29781/5595/1778/5516/4000/115106/4926/22995/55559/81929/5684/5720/54908/55143/9631/5525/10142/1058/991/79019/5862/80152/5690/1063/95681/5717/9491/10783/23421/55920/79023/23636/10735/10197/7443/112714/23141/1781/7316/10213/80321/53371/26003/4085/9688/55166/10121/5715/84131/5701/5685/3320/8815/5686/79003/9126/9918/10733/23399/4751/9232/5527/9700/27175/80254/5716/701/9662/55142/64689/8481/5693/5721/55755/8480 293 Bunyavirus R-HSA-927802 Nonsense-Mediated Decay (NMD) 112/4506 115/10654 3.1009716349792225e-38 2.1613772295805182e-36 1.0200564588747443e-36 6158/9887/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/55629/6169/6175/6218/65109/6173/6167/116832/6156/6143/5520/6139/23381/5518/3921/6208/6170/5515/6203/6147/6222/26019/2935/6134/22794/6155/4116/6231/6142/23521/1981/6207/6233/6188/23049/5976/200916/6122/6230/6194/2107/6166/56006/6136/6125/6232/6160/55110/6193/6210/6229/6205/55181/140801/6235/6181/9939/7311/6223/25873/23708/9045/6187/65110/6168/22916/6157/6137/10921/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/4686/6209/11224/6165/6130/6204/6228/55802/6124/6189/23293/9775/6135/6201/6161/6133 112 Bunyavirus R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 112/4506 115/10654 3.1009716349792225e-38 2.1613772295805182e-36 1.0200564588747443e-36 6158/9887/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/55629/6169/6175/6218/65109/6173/6167/116832/6156/6143/5520/6139/23381/5518/3921/6208/6170/5515/6203/6147/6222/26019/2935/6134/22794/6155/4116/6231/6142/23521/1981/6207/6233/6188/23049/5976/200916/6122/6230/6194/2107/6166/56006/6136/6125/6232/6160/55110/6193/6210/6229/6205/55181/140801/6235/6181/9939/7311/6223/25873/23708/9045/6187/65110/6168/22916/6157/6137/10921/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/4686/6209/11224/6165/6130/6204/6228/55802/6124/6189/23293/9775/6135/6201/6161/6133 112 Bunyavirus R-HSA-69239 Synthesis of DNA 115/4506 119/10654 4.238201401686893e-38 2.8133584542626326e-36 1.327757331355543e-36 8454/5689/2237/9134/11065/5682/7321/8697/5982/143471/5705/5709/5422/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/84296/6117/29882/5001/5558/5696/5691/7314/996/5718/6118/23594/5700/122706/5707/64785/23198/898/3978/5557/890/51433/9861/6502/5698/5692/5985/5713/119504/4175/5710/5984/7324/5719/64682/6233/23649/5424/4999/4172/5000/8318/246184/54107/4173/5706/8881/5425/5714/5111/6119/5688/5687/5427/5708/81620/10393/5704/51343/23595/7311/25906/51659/5983/5694/4176/56655/1017/5684/5720/9837/5690/5717/9491/6500/10197/7316/10213/5426/4171/5715/5701/5685/5686/5716/5981/5693/5721 115 Bunyavirus R-HSA-8957275 Post-translational protein phosphorylation 106/4506 108/10654 2.3507663592289027e-37 1.4895310476204957e-35 7.029803705828057e-36 56955/4240/3270/9210/10272/2153/7857/29106/91851/6696/51156/1435/265/11098/10130/2200/80341/375056/1114/720/10117/3956/3569/54972/2519/8720/7018/10618/11167/813/5179/8074/51246/348/4924/3484/102/8614/336/6694/4148/174/57104/721/2335/7466/116519/2266/51280/7076/2243/84141/3488/8542/4221/351/4052/7184/56975/334/3912/338/64856/335/5611/197/3053/3895/5624/1000/54757/8404/255738/3913/652/57719/147111/2719/3487/3371/54587/401138/3486/7425/6383/3827/3490/5589/2621/3915/5768/1471/1462/10232/462/3698/5265/1758/258/11320/5954/213/10970/5034/1356/718 106 Bunyavirus R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 109/4506 112/10654 3.948705260839884e-37 2.3932587537438255e-35 1.129492351498823e-35 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/6202/6169/6175/6218/6173/6167/116832/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/200916/6122/1968/6230/8669/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/9669/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 109 Bunyavirus R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 108/4506 111/10654 9.214087723872469e-37 5.351849286282592e-35 2.525791590973813e-35 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/116832/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/200916/6122/1968/6230/8669/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 108 Bunyavirus R-HSA-6807878 COPI-mediated anterograde transport 100/4506 101/10654 1.3253485254202253e-36 7.390143377743176e-35 3.4877592774216457e-35 6811/6711/11014/51807/286/347688/5861/10381/7278/1780/9570/8655/84516/832/55738/7846/113457/51226/9382/3630/81027/6709/10652/54732/51272/51164/79861/2801/377/10466/1315/8615/11316/91949/8729/23423/10376/1314/10540/51332/378/26286/26958/140735/10959/2348/84364/22820/84617/22796/11258/6712/1783/10382/93661/55860/830/7277/10671/966/1639/10282/6710/8775/81876/11015/347733/51143/10383/84790/10945/7280/829/1778/11070/25839/51014/83548/63908/112714/1604/1781/57731/10121/2804/9527/57511/8774/10972/381/6708/4905/9276/287/375/84342/64689/288/22818/372 100 Bunyavirus R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 160/4506 185/10654 2.9680229137329638e-36 1.5913169006706735e-34 7.510179437583411e-35 6158/5393/6138/6227/6206/6234/6191/6128/6132/10557/6129/6176/10528/84135/27340/27043/6224/6146/6154/88745/6202/51096/6169/55272/6175/6218/5394/6173/11102/6167/28987/116832/23481/51077/6156/117246/6143/6139/23160/26168/3921/10607/10799/11103/51388/6208/6170/22984/10813/9136/6203/23246/54913/6147/6222/1454/56902/51602/6134/6155/9724/6231/6142/23521/54555/10171/5822/6207/10969/10556/6233/6188/54881/1453/4691/23016/200916/6122/79897/6230/2091/55127/8602/6194/6166/10436/8780/9277/84128/6136/6125/6232/134430/6160/92856/65083/6193/6210/6229/6205/11056/9790/140801/6235/55720/6181/55759/705/7311/6223/25873/26354/56915/51202/9045/57647/6187/6168/6157/6137/79050/22894/84946/6144/9349/55813/4736/57418/22803/51121/6159/25879/6217/81887/6152/57050/51065/6141/6123/55781/6164/6209/11224/6165/6130/6204/6228/10199/6124/25926/83732/27341/6189/6135/6201/6161/54512/10885/6133/9188 160 Bunyavirus R-HSA-69620 Cell Cycle Checkpoints 228/4506 293/10654 3.422482337164353e-36 1.7670149548174473e-34 8.339381913168502e-35 5689/55839/11130/9134/11065/6249/5682/9156/9735/7531/7486/7321/5526/10971/8697/9212/5982/7533/2810/147841/348995/11200/143471/472/57122/5705/1780/23122/5048/5709/4174/5695/8655/84515/23279/4194/4998/5711/2491/4683/10926/5683/990/1060/165918/84126/5699/5702/8900/51529/29945/8924/11004/51434/55388/672/9184/5518/6117/29882/7334/5001/23332/7465/51230/10726/81930/55746/5696/5691/7314/996/5515/5718/6118/79682/10403/23594/25936/5700/122706/5707/51588/51720/23198/63967/898/64105/7534/332/5528/993/890/983/51433/9861/79902/3796/9656/5519/81565/5698/5692/5985/5713/91687/119504/11243/4175/5710/7157/5984/7324/83540/5719/64682/6233/7514/7158/54820/6396/64946/9793/5884/5810/140735/4999/4172/4928/5903/5000/8318/246184/51512/1029/80776/1783/401541/7532/79172/4173/5706/9133/79980/6232/580/8881/11073/891/5501/641/5714/6119/9183/3364/10524/5688/1062/699/5687/5708/22919/5529/51143/1111/10393/5704/23595/7311/25906/5347/84643/5983/5694/4176/7529/1778/5516/1017/81929/5684/5720/54908/55143/5883/5525/1058/991/79019/10111/8317/80152/5690/1063/5717/1027/9491/23421/545/55920/79023/10197/7336/29086/1781/7316/10213/4085/1026/4171/55166/5715/9088/7341/5701/5685/5686/995/79003/5527/5716/701/5932/9025/79184/5693/5721/4193 228 Bunyavirus R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic 98/4506 99/10654 7.450713074522717e-36 3.7093907235302385e-34 1.7506374705175558e-34 11014/64837/11127/51807/53407/347688/3798/5861/10381/7278/285643/55738/10112/64147/7846/113457/51226/81027/11004/10749/81930/54732/60561/113220/79861/3797/29127/55605/377/1315/3796/124602/11316/55614/89953/56992/8729/23423/10376/1314/3835/147700/3833/378/9493/26286/26958/10959/3831/84364/22820/84617/55850/9585/10382/3832/7277/9554/23303/8775/26153/81876/9183/1062/11015/146909/347733/662/90990/23046/10383/24137/84790/84643/10945/51594/22920/7280/55582/9371/51014/23095/63908/112714/6836/547/8774/10972/381/4905/3834/9276/55083/3799/375/221458/22818/372 98 Bunyavirus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 150/4506 171/10654 1.2374985301973009e-35 5.948527417569095e-34 2.8073923098849838e-34 6158/5689/6138/6227/6206/6234/6191/6128/5682/6132/6129/6176/6224/6146/6154/26986/143471/6202/5705/6169/5709/6175/9978/6218/5695/65109/6173/6167/5711/116832/1605/5683/6156/5699/6143/5702/6139/3921/6208/5696/6170/5691/7314/5718/6203/6147/5700/122706/5707/6222/23198/26019/2935/6134/22794/6155/4116/6231/9861/6142/23521/5698/5692/5713/1981/5710/6207/5719/6233/6188/200916/6122/6230/6194/2107/6166/6136/6125/5706/6232/6160/55110/5714/6193/6210/6229/6205/5688/5687/5708/140801/6235/6181/9939/5704/7311/6223/25873/23708/5694/9045/6187/65110/6168/22916/6157/6137/10921/6144/5684/9349/4736/5720/51121/6159/6217/6152/5690/5717/9491/51065/6141/23053/6123/10197/6164/4686/7316/10213/6209/11224/6165/6130/5715/6204/5701/6228/5685/5686/6124/8453/5716/6189/9775/6135/6201/6161/5693/5721/6133 150 Bunyavirus R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 108/4506 112/10654 1.5137941422575342e-35 7.0340967810233425e-34 3.319723996178803e-34 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/55176/6224/6146/6154/6202/6169/6175/6218/6728/6173/6167/116832/6156/6143/6139/6745/3921/23478/6208/6170/6203/10952/6147/6222/6727/6184/58477/6134/6747/6731/6155/6729/6231/6142/23521/6185/6207/6726/6233/6188/200916/6122/6230/6194/6166/1650/6136/6125/6232/6160/6748/29927/60559/6746/6193/6210/6229/6205/28972/140801/6235/6181/23471/7311/6223/25873/6730/90701/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/23480/6164/6209/11224/6165/6130/6204/6228/6124/6189/9789/6135/6201/6161/6133 108 Bunyavirus R-HSA-69242 S Phase 143/4506 161/10654 2.069325224592826e-35 9.30528826800774e-34 4.39160701314267e-34 8454/5689/2237/9134/11065/5682/7321/8697/5982/5925/143471/5705/5709/5422/9978/1869/4174/5753/5695/84515/4609/4998/5711/5928/5683/990/5699/5702/8900/51529/29945/51434/84296/157570/6117/29882/5001/7465/5558/5696/5691/7314/996/5718/6118/23594/7027/5700/122706/5707/64785/23198/898/3978/5557/993/890/51433/9861/2932/6502/5698/10000/5692/5985/5713/119504/595/4175/5710/5984/7324/5719/64682/6233/23649/1163/5424/4999/4172/1019/5000/8318/246184/54107/4173/5706/8881/5885/4331/5425/5714/5111/6119/5688/5687/5427/5708/1874/8243/81620/10393/208/5704/55957/51343/23595/7311/25906/51659/5983/5694/4176/56655/1017/5684/994/5720/207/9837/5690/5717/1027/9491/6500/10735/10197/4149/7316/10213/1026/5426/4171/5715/5701/5685/5686/9126/5716/5981/1022/5693/5721 143 Bunyavirus R-HSA-8868773 rRNA processing in the nucleus and cytosol 165/4506 195/10654 8.17051672028457e-35 3.559281346273966e-33 1.679793733611137e-33 6158/5393/6138/6227/6206/6234/6191/6128/6132/10557/6129/55226/6176/10528/84135/27340/27043/6224/6146/6154/88745/6202/51096/6169/55272/6175/6218/5394/6173/11102/6167/28987/116832/23481/51077/6156/117246/6143/6139/23160/26168/3921/10607/10799/11103/51388/6208/6170/22984/10813/9136/6203/23246/54913/6147/27292/6222/1454/56902/51602/6134/6155/9724/6231/6142/23521/54555/10171/5822/6207/10969/10556/6233/6188/54881/1453/4691/23016/200916/6122/79897/6230/2091/55651/55127/8602/6194/6166/10436/8780/9277/84128/6136/6125/4839/6232/134430/6160/92856/65083/6193/6210/6229/6205/11056/9790/140801/6235/55720/6181/55759/705/7311/6223/25873/26354/56915/51202/9045/57647/6187/6168/6157/6137/79050/22894/84946/6144/9349/55813/4736/57418/22803/51121/6159/25879/6217/81887/6152/57050/51065/6141/6123/55781/6164/6209/11224/6165/6130/6204/1736/6228/10199/6124/25926/83732/27341/6189/6135/6201/6161/54512/10885/6133/9188 165 Bunyavirus R-HSA-376176 Signaling by ROBO receptors 179/4506 218/10654 3.5003565044731006e-34 1.478635444616819e-32 6.978382185951159e-33 6158/5689/6138/6227/7852/6206/6234/6191/6128/5682/6132/10298/6129/6176/5578/6224/6146/6154/26986/143471/6202/5705/6169/8829/23122/5709/6175/9978/6218/5695/65109/6173/6167/5711/116832/1605/5683/6156/5699/6143/5702/6139/10487/3921/23332/5062/6208/5696/6170/5691/7314/5879/5718/25/6203/6147/5700/122706/5707/5567/6222/23198/26019/2935/6134/22794/6155/4116/6714/6231/9861/6142/23521/10486/5698/5692/5713/1981/5710/6207/5719/6233/6188/5217/200916/6122/6230/6194/2107/6166/56924/6136/6125/5706/6232/6160/55110/5714/6193/6210/6229/6205/5566/4650/5688/5687/5708/5063/140801/6235/6181/998/9939/6654/5704/7311/6223/25873/387/23708/5694/5058/9045/6187/65110/6168/22916/6157/6137/10921/6144/55740/5684/9349/4736/5720/51121/2817/6159/4690/6217/6152/5690/5717/9491/51065/6141/23053/6123/10197/6164/4686/7316/10213/5216/6209/11224/6165/6130/5715/6204/5701/6228/5576/5685/5686/7408/6124/8453/5716/23380/6189/9775/6135/6201/6161/5693/5721/6133 179 Bunyavirus R-HSA-2262752 Cellular responses to stress 330/4506 479/10654 2.546424896278093e-33 1.0440342074740181e-31 4.927292755956062e-32 1912/23165/5689/3725/6782/9134/11065/573/4790/5682/64344/7531/1915/11133/7321/51807/817/6045/8697/9530/347688/23677/27327/80012/7295/5925/3091/348995/143471/472/10381/57122/5705/7278/3313/1780/7001/23511/5709/9978/1869/5695/3305/8655/84516/1911/832/26277/23279/4194/91582/5711/5928/1432/1387/4683/7846/259217/23225/113457/5683/3309/23512/5699/126374/25994/7428/5702/192669/9531/81027/8900/51529/4001/29945/8091/8131/2056/51434/2475/3306/27000/6196/9972/23411/8021/4343/6117/6197/29882/3312/4217/54386/3569/55746/5696/5691/7296/7314/51164/996/51182/5718/818/3303/7014/6118/51606/79861/2876/5606/7027/526/5700/122706/5707/2146/2936/5594/3308/84335/23198/898/10049/10013/27244/3337/10762/847/7323/890/5970/9261/6667/51433/9861/79902/5598/9883/2932/84733/529/5698/5692/5713/119504/10376/6195/5710/3301/533/10540/7157/7324/5719/64682/6233/2353/8726/6396/1535/129401/523/201163/26523/405/3297/57521/140735/28956/84617/4928/1019/5903/83667/55706/7175/653361/5241/11258/9448/246184/112399/1029/1783/25828/8535/84962/10382/93661/5931/10294/55860/830/7013/7277/1051/1410/50488/5706/10671/8881/527/6774/1639/5714/4927/64223/6119/26353/3552/10524/5688/5687/57805/3281/3310/2908/347733/5708/5602/7266/25824/51143/816/6648/8086/10393/5704/3326/51343/7311/367/25906/3397/2034/79400/57634/10383/84790/55662/648/5694/3304/23466/6416/10641/7280/10728/829/5595/1778/1017/815/25913/81929/5684/5720/9631/3159/7290/116835/10111/7422/5690/5717/1027/9491/545/79023/23636/10197/192670/10808/112714/3490/4306/1781/7316/10213/10935/53371/1026/9532/54205/2289/9588/9688/10121/7415/1871/6647/8994/7322/5715/5701/5685/8649/3320/65057/5686/2033/1021/6767/25842/8453/23135/10963/22824/57600/5609/5716/9529/5599/54583/5052/1536/96459/5693/5721/55466/2288/5034/8480/10919/318/4193/2950/9296/23043 330 Bunyavirus R-HSA-72689 Formation of a pool of free 40S subunits 98/4506 101/10654 4.316041445068088e-33 1.71901764983569e-31 8.112859859150542e-32 6158/6138/6227/6206/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/8663/23521/6207/6233/51386/6188/200916/6122/6230/8669/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/8664/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 98 Bunyavirus R-HSA-69206 G1/S Transition 120/4506 131/10654 5.099703096642616e-33 1.974718365755502e-31 9.319632852051565e-32 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/4998/5711/5928/10926/5683/990/5699/5702/8900/55388/5518/6117/5001/7465/5558/5696/5691/7314/5515/6241/5718/6118/23594/7027/5700/5707/898/5557/993/890/1876/983/9861/5519/6502/5698/10000/5692/5713/595/4175/5710/5719/6233/7298/23649/1719/1163/4999/4172/26271/1019/5000/8318/54107/4173/5706/891/4331/5714/5111/51053/6119/5688/5687/5427/5708/1874/81620/208/5704/29935/55957/23595/7311/5694/4176/5516/56655/1017/5684/5720/8317/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1026/5426/4171/5715/5701/5685/5686/3065/5716/1022/5693/5721/7083 120 Bunyavirus R-HSA-5663202 Diseases of signal transduction 272/4506 377/10654 6.847249443811863e-33 2.579747493155064e-31 1.2175052353861777e-31 5295/8454/2308/5689/374/4893/11052/5335/71/79718/5682/892/5526/817/1452/7039/9530/613/143471/23385/2064/5705/54845/5431/5435/5709/9978/5433/5695/9759/9227/5605/4609/145226/4089/22938/5037/3549/5711/1387/3717/4088/2244/5683/145957/324/2534/3690/408/5699/6400/8312/11064/5439/5702/4296/5894/9542/2885/2475/8660/51009/8826/9846/5518/57534/6469/4140/7040/3845/3265/80351/4763/5696/7750/5691/7314/5879/5515/5718/818/8805/1839/26127/5290/3667/6801/79885/2065/2648/9734/55869/5700/3815/122706/5707/10956/8844/51564/7094/5594/3280/2069/84335/8074/7249/23198/7414/10013/23164/2260/5438/5528/83933/102/57085/6714/2099/50846/9861/5519/9061/8850/399687/2932/7046/5698/10000/5692/5713/2335/1445/5710/3066/2280/5719/6233/2266/7409/27248/3932/2931/2243/6777/369/801/5781/5663/57670/253260/805/5170/2963/5434/7276/6464/572/283455/5436/4303/4041/409/5706/6199/84447/673/6774/4233/8658/5714/6772/6934/64223/10014/2962/8503/5688/5159/5687/5708/3084/5529/816/4087/208/6654/5704/10718/56829/7048/7311/7450/1956/11160/60/9444/2549/5694/5950/4851/5432/22916/11140/7529/5595/5516/4000/1147/27044/815/5440/5684/22906/8841/685/5720/8087/1487/2309/5604/1499/10018/5525/10142/842/139285/5430/23462/207/5690/5717/1027/9491/6500/5441/10197/2100/4686/7316/10213/1950/9611/1026/50852/7415/5715/2261/5701/867/5437/5685/2255/3164/3320/5686/2033/54894/391/55294/5728/3065/2066/5527/5716/5906/4254/5296/3516/5693/5721/5245/4193 272 Bunyavirus R-HSA-72312 rRNA processing 169/4506 205/10654 9.471076420737176e-33 3.4743896132914795e-31 1.6397292972190402e-31 6158/5393/6138/6227/6206/6234/6191/6128/79922/6132/10557/6129/55226/6176/10528/84135/27340/27043/6224/6146/6154/88745/6202/51096/6169/55272/6175/6218/5394/6173/11102/6167/28987/116832/23481/51077/6156/117246/6143/6139/23160/26168/3921/10607/10799/11103/51388/6208/6170/22984/10813/60528/9136/6203/23246/54913/6147/27292/6222/1454/56902/51602/6134/6155/9724/6231/6142/23521/54555/10171/5822/6207/10969/10556/6233/6188/54881/1453/4691/23016/200916/6122/79897/6230/2091/55651/55127/8602/6194/6166/3028/10436/8780/9277/84128/6136/6125/4839/6232/134430/6160/92856/65083/6193/6210/6229/6205/11056/9790/140801/6235/55720/6181/55759/705/7311/6223/25873/26354/56915/51202/9045/57647/6187/6168/6157/6137/79050/22894/84946/6144/9349/55813/4736/57418/22803/51121/6159/25879/6217/81887/6152/57050/51065/6141/6123/55781/6164/54931/6209/11224/6165/6130/6204/1736/6228/10199/6124/25926/83732/27341/6189/6135/6201/6161/54512/10885/6133/9188 169 Bunyavirus R-HSA-72613 Eukaryotic Translation Initiation 111/4506 119/10654 1.6434948303442003e-32 5.727579483749538e-31 2.7031164972766458e-31 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/116832/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/200916/6122/1968/6230/8669/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/9669/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/8892/6133 111 Bunyavirus R-HSA-72737 Cap-dependent Translation Initiation 111/4506 119/10654 1.6434948303442003e-32 5.727579483749538e-31 2.7031164972766458e-31 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/116832/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/200916/6122/1968/6230/8669/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/9669/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/8892/6133 111 Bunyavirus R-HSA-69052 Switching of origins to a post-replicative state 89/4506 90/10654 1.7437924119842425e-32 5.928894200746424e-31 2.7981264633893493e-31 8454/5689/9134/11065/5682/7321/8697/143471/5705/5709/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/29882/5001/5696/5691/7314/996/5718/23594/5700/122706/5707/23198/898/890/51433/9861/6502/5698/5692/5713/119504/4175/5710/7324/5719/64682/6233/4999/4172/5000/246184/4173/5706/8881/5714/5688/5687/5708/81620/10393/5704/51343/23595/7311/25906/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 89 Bunyavirus R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 92/4506 94/10654 3.6288518986254776e-32 1.2044332254009323e-30 5.684291821155197e-31 114791/10844/440145/7531/11190/203068/54801/51807/347688/79441/10381/5116/7278/5048/8655/9702/7846/7840/113457/11064/81027/5518/55835/29922/23332/93323/79861/1454/983/79959/80097/10376/10540/85378/54930/54820/1453/27229/9793/84617/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/9738/1639/55722/4957/5566/7283/347733/22919/10426/22994/1069/5577/10383/5347/84790/80184/22897/5108/7280/10806/1778/115106/4926/22995/55559/10142/95681/112714/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 92 Bunyavirus R-HSA-5620912 Anchoring of the basal body to the plasma membrane 95/4506 98/10654 5.404564027085806e-32 1.75208424505991e-30 8.268916810106804e-31 79867/7531/11190/203068/54801/85302/79441/5116/5048/22832/8655/9702/132320/7846/7840/11064/84902/5518/55835/23332/93323/1454/54806/91147/983/79959/10540/117177/57545/26005/54930/54820/23322/1453/9793/4218/11258/22981/8636/54903/80776/7532/55125/10382/121441/7277/9814/23354/146057/9738/1639/55722/4957/5566/7283/22919/27077/22994/4867/1069/5577/10383/5347/80184/22897/5108/261734/57787/10806/9657/1778/115106/22995/55559/10142/51134/95681/1781/80321/8766/79598/10121/347240/84131/3320/79600/10733/4751/80254/26123/9662/55142/8481/51259/55755 95 Bunyavirus R-HSA-948021 Transport to the Golgi and subsequent modification 155/4506 185/10654 9.724043448496411e-32 3.0807537652736358e-30 1.4539538649067603e-30 6811/23256/374/6711/11014/126003/10960/2153/51807/286/10484/7039/347688/5861/10381/7278/1780/9570/90411/8655/84516/832/3998/55738/7846/113457/51226/9382/375056/9632/3630/81027/6709/79090/10652/54732/51272/51164/58485/1294/79861/9117/10342/2801/377/10466/2517/22872/1315/81562/8615/11316/91949/8729/254263/23423/10376/1314/10540/51332/83696/51128/27095/6399/7109/378/6396/79694/26286/1453/26958/10175/140735/10959/2348/84364/22820/84617/22796/11258/6712/2890/1783/10382/10802/93661/55860/2157/830/7277/10671/9554/966/11196/1639/149111/10282/6710/8775/81876/4124/11015/347733/51143/79748/51693/5537/9871/10383/84790/10945/1075/7280/829/1778/9919/10113/51399/11070/25839/55291/51014/122553/26984/83548/63908/112714/1604/1781/57731/1522/10121/2804/9527/57511/22870/5265/8774/10972/381/6708/4905/4245/11320/89866/2683/9276/287/375/84342/64689/288/10427/22818/372 155 Bunyavirus R-HSA-453279 Mitotic G1-G1/S phases 131/4506 149/10654 1.7665425351763614e-31 5.47235620896855e-30 2.5826645251116395e-30 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/4998/5711/5928/10926/3717/5683/990/5699/5702/5520/8900/55388/5518/6117/5001/7465/5558/5696/5691/7314/5515/6241/5718/6118/25/23594/7027/5700/5707/7153/898/5557/993/890/1876/983/6714/9861/5519/6502/5698/10000/5692/5713/595/4175/5710/5719/6233/7298/23649/1719/1163/1859/4999/4172/26271/1019/5000/8318/1029/54107/4173/5706/891/4331/5714/5111/51053/6119/5688/5687/5427/4067/5708/1874/81620/208/5704/29935/55957/23595/7311/5694/4176/5516/56655/1017/894/5684/5720/8317/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1026/5426/4171/1871/5715/5701/5685/5686/1021/3065/5716/1022/5693/5721/7083 131 Bunyavirus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 85/4506 86/10654 5.446857940280453e-31 1.6155148869682876e-29 7.624381215398171e-30 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 85 Bunyavirus R-HSA-453276 Regulation of mitotic cell cycle 85/4506 86/10654 5.446857940280453e-31 1.6155148869682876e-29 7.624381215398171e-30 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 85 Bunyavirus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 92/4506 95/10654 6.740506229820547e-31 1.9575553509103837e-29 9.23863244218825e-30 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/2935/6134/6155/6231/6142/23521/1981/6207/6233/6188/5976/200916/6122/6230/6194/2107/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/23708/9045/6187/6168/22916/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/4686/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 92 Bunyavirus R-HSA-156842 Eukaryotic Translation Elongation 90/4506 93/10654 3.616653152301066e-30 1.0289009172056503e-28 4.8558715793515935e-29 6158/6138/6227/6206/6234/6191/6128/6132/1917/6129/1915/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6166/1938/6136/6125/1937/6232/6160/1933/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/1936/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 90 Bunyavirus R-HSA-391251 Protein folding 96/4506 101/10654 4.045930475051294e-30 1.1280054164443007e-28 5.323592730330651e-29 2788/6000/9134/1459/2770/51807/10528/1460/10381/7278/2775/10576/1457/7846/113457/7411/2782/81027/10574/6468/10564/54461/10693/8877/2773/5201/2787/402/79861/5204/10575/6903/10681/898/10517/8786/2792/10471/26985/26330/2785/10376/2783/26190/2784/10238/7157/2771/83752/2791/6904/5202/26224/84617/2629/8237/10382/7277/63971/6774/26272/26270/347733/55135/5082/2786/10383/60/84790/22948/7280/84261/9628/10694/8841/54331/22803/59345/8787/5203/51764/94235/112714/7203/908/55970/6902/6905/11328/1155/2793/6950/55294/6499/26234/2790 96 Bunyavirus R-HSA-8953897 Cellular responses to external stimuli 331/4506 493/10654 4.383391708311944e-30 1.1981270669385979e-28 5.654530067481869e-29 1912/23165/5689/3725/6782/9134/11065/573/4790/5682/64344/7531/1915/11133/7321/51807/817/6045/8697/9530/347688/23677/27327/80012/7295/5925/3091/348995/143471/472/10381/57122/5705/7278/3313/1780/7001/23511/5709/9978/1869/5695/3305/8655/84516/1911/832/26277/23279/4194/91582/5711/5928/1432/1387/4683/7846/259217/23225/113457/5683/3309/23512/5699/126374/25994/7428/5702/192669/9531/81027/8900/51529/4001/29945/8091/8131/2056/51434/2475/3306/27000/6196/9972/23411/8021/4343/6117/6197/29882/3312/4217/54386/3569/55746/5696/5691/7296/7314/51164/996/51182/5718/818/3303/7014/6118/51606/79861/2876/5606/7027/526/5700/122706/5707/2146/2936/5594/3308/84335/23198/898/10049/10013/27244/3337/10762/847/7323/890/5970/9261/6667/51433/9861/79902/5598/9883/2932/84733/529/5698/5692/5713/119504/10376/6195/5710/3301/533/10540/7157/7324/5719/64682/6233/2353/8726/6396/1535/129401/523/201163/26523/405/3297/57521/140735/28956/84617/4928/1019/5903/83667/55706/7175/653361/5241/11258/9448/246184/112399/1029/1783/25828/8535/84962/10382/93661/5931/10294/55860/830/7013/7277/1051/1410/50488/5706/10671/8881/527/6774/1639/5714/4927/64223/6119/26353/3552/10524/5688/5687/57805/3281/3310/2908/347733/5708/5602/7266/25824/51143/816/6648/8086/10393/5704/3326/51343/7311/367/25906/3397/2034/79400/57634/10383/84790/55662/648/5694/3304/23466/6416/10641/7280/10728/829/5595/1778/1017/815/25913/81929/5684/5720/9631/3159/7290/116835/10111/7422/5690/5717/1027/9491/545/79023/23636/10197/192670/10808/112714/3490/4306/1781/7316/10213/10935/53371/1026/9532/54205/2289/9588/9688/10121/7415/1871/6647/8994/7322/5715/5701/5685/8649/3320/65057/5686/2033/1021/6767/25842/8453/23135/10963/22824/57600/5609/5716/9529/4520/5599/54583/5052/1536/96459/5693/5721/55466/2288/5034/8480/10919/318/4193/2950/9296/23043 331 Bunyavirus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 86/4506 88/10654 5.948675547916542e-30 1.594702637268396e-28 7.526158334914654e-29 8454/7531/11190/203068/54801/79441/5116/5048/8655/6790/9702/7846/7840/11064/5518/55835/23332/93323/7314/8945/4659/1454/983/79959/10540/6233/54930/54820/1453/9793/4218/5500/11258/22981/8636/7532/84962/55125/10382/121441/7277/9133/9814/23354/891/9738/1639/55722/4957/5566/7283/22919/22994/79866/1069/5577/7311/10133/10383/5347/80184/22897/5108/4660/10806/1778/115106/22995/55559/10142/95681/6500/1781/7316/80321/10121/84131/23291/3320/10733/4751/80254/9662/55142/8481/55755 86 Bunyavirus R-HSA-69002 DNA Replication Pre-Initiation 83/4506 85/10654 7.577049219829515e-29 1.9929069080079894e-27 9.405473212300788e-28 5689/5682/143471/5705/5709/5422/1869/4174/5695/84515/4998/5711/10926/5683/990/5699/5702/55388/6117/5001/5558/5696/5691/7314/5718/6118/23594/5700/122706/5707/23198/5557/9861/5698/5692/5713/4175/5710/5719/6233/23649/4999/4172/5000/8318/54107/4173/5706/5714/51053/6119/5688/5687/5427/5708/81620/5704/29935/23595/7311/5694/4176/56655/1017/5684/5720/8317/5690/5717/9491/10197/7316/10213/5426/4171/1871/5715/5701/5685/5686/5716/5693/5721 83 Bunyavirus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 79/4506 80/10654 9.432949186369176e-29 2.4350983640367834e-27 1.1492384486317222e-27 8454/5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 79 Bunyavirus R-HSA-156902 Peptide chain elongation 86/4506 89/10654 1.0351537185056888e-28 2.5315864624507546e-27 1.1947757600481175e-27 6158/6138/6227/6206/6234/6191/6128/6132/6129/1915/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6166/1938/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 86 Bunyavirus R-HSA-192823 Viral mRNA Translation 86/4506 89/10654 1.0351537185056888e-28 2.5315864624507546e-27 1.1947757600481175e-27 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/5611/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/2926/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 86 Bunyavirus R-HSA-3371556 Cellular response to heat stress 86/4506 89/10654 1.0351537185056888e-28 2.5315864624507546e-27 1.1947757600481175e-27 23165/6782/573/7531/1915/817/9530/348995/472/57122/3313/23511/3305/23279/91582/1387/259217/23225/3309/9531/2475/3306/27000/9972/23411/8021/6117/3312/55746/51182/818/3303/6118/5594/3308/84335/10049/10013/3337/10762/9261/79902/9883/2932/6396/129401/3297/57521/4928/5903/55706/7175/1410/4927/64223/6119/26353/57805/3281/3310/7266/816/8086/3326/3304/10728/5595/815/81929/9631/116835/545/79023/23636/10808/53371/9532/9688/7415/3320/2033/6767/22824/9529/2288/8480 86 Bunyavirus R-HSA-390466 Chaperonin-mediated protein folding 90/4506 95/10654 5.555911195241948e-28 1.3353345183047027e-26 6.302077127089325e-27 2788/6000/9134/1459/2770/51807/10528/1460/10381/7278/2775/10576/1457/7846/113457/7411/2782/81027/10574/6468/10564/54461/10693/8877/2773/5201/2787/79861/5204/10575/10681/898/10517/8786/2792/10471/26985/26330/2785/10376/2783/26190/2784/10238/7157/2771/83752/2791/5202/26224/84617/2629/8237/10382/7277/63971/6774/26272/26270/347733/55135/5082/2786/10383/60/84790/22948/7280/84261/9628/10694/8841/54331/22803/59345/8787/5203/51764/94235/112714/7203/908/55970/11328/2793/6950/55294/6499/26234/2790 90 Bunyavirus R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 80/4506 82/10654 9.615898035525354e-28 2.2340936435870573e-26 1.0543747845970782e-26 114791/10844/440145/7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/1454/983/79959/80097/10540/85378/54930/54820/1453/27229/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/728642/9738/1639/55722/4957/5566/7283/22919/984/10426/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 80 Bunyavirus R-HSA-380287 Centrosome maturation 80/4506 82/10654 9.615898035525354e-28 2.2340936435870573e-26 1.0543747845970782e-26 114791/10844/440145/7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/1454/983/79959/80097/10540/85378/54930/54820/1453/27229/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/728642/9738/1639/55722/4957/5566/7283/22919/984/10426/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 80 Bunyavirus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 76/4506 77/10654 1.2366567691756212e-27 2.826064813493141e-26 1.3337540651160713e-26 5689/5682/51807/63943/347688/143471/10381/5705/7278/5709/5695/5711/7846/113457/5683/5699/5702/81027/5696/5691/7314/5718/79861/5700/122706/5707/23198/983/9861/5698/5692/5713/10376/5710/7157/5719/6233/84617/51512/10382/7277/5706/9133/891/5714/5688/5687/347733/5708/22919/5704/3326/7311/10383/5347/84790/5694/7280/5684/5720/5690/5717/9491/10197/112714/7316/10213/1026/5715/5701/5685/3320/5686/5716/5693/5721 76 Bunyavirus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 75/4506 76/10654 2.9142563768468923e-27 6.552376434394465e-26 3.092377309896957e-26 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 75 Bunyavirus R-HSA-162909 Host Interactions of HIV factors 113/4506 129/10654 5.4527745215167065e-27 1.2065345528562364e-25 5.69420898236916e-26 23165/5689/162/5682/1174/348995/143471/57122/5705/23511/5709/9978/5695/292/23279/5711/23225/5683/2534/5699/5702/3836/163/9972/8021/1794/904/5062/55746/5696/5691/7314/5879/5718/8945/51606/161/5700/122706/5707/23198/10762/9861/79902/11168/9883/5698/5692/5713/5710/5478/5719/6233/7514/1025/3932/6396/129401/1175/8907/60489/1173/4928/5903/55706/7175/4869/5706/160/293/920/5714/4927/5688/5687/5708/5901/8086/5704/7311/5694/3837/81929/164/5684/8065/5720/9631/3159/5690/5717/9491/6500/79023/23636/10197/7316/10213/53371/3055/9688/5715/5701/5685/8815/5686/5716/9844/375/5693/5721/8480/291 113 Bunyavirus R-HSA-6798695 Neutrophil degranulation 317/4506 480/10654 6.786620394701988e-27 1.472397380033775e-25 6.948941799600616e-26 8773/9798/1727/5689/8804/8514/4893/9218/4790/960/1823/1511/5657/57826/1915/203068/9761/383/654364/8836/2268/5211/1460/29108/23385/6280/535/10577/55276/5912/5709/5269/10576/1509/5695/2896/8655/7133/3106/3074/3417/3043/2548/2204/1432/3920/5476/8904/5683/201294/2588/3482/4311/80142/2444/5702/566/9961/51552/10075/56729/10487/6709/6093/160364/441864/8826/9522/1794/4282/3608/2720/3312/3071/387263/2665/51719/1654/2519/6037/5879/51316/2717/5718/1992/3303/58485/2934/80331/6518/56954/161/56888/5707/2358/8972/823/5594/4831/23406/5787/6727/7414/258010/4257/51209/847/2517/25852/22918/8895/5834/1315/102/84443/4069/5317/965/4973/9861/5870/410/6556/411/28988/226/2821/5553/199675/978/55832/23601/5713/1/2495/3728/3614/10043/4125/5478/5719/374395/5328/5580/23191/3685/302/634/1729/5236/6036/1535/2040/230/317/23250/2990/5663/7879/8907/671/28956/30/10450/25801/1828/3903/23352/7276/83858/4332/10159/1938/8635/51646/1650/338339/3684/387921/3163/54472/101/3577/2215/55860/10549/2760/5864/3958/963/79980/5836/6993/11240/6616/5329/966/5611/84061/527/6279/6515/11322/5337/10092/170482/197/8694/140885/2171/3310/1832/5708/55313/3615/11314/138050/23218/51143/80301/4860/6386/10788/3326/10857/10097/3916/53831/10383/387/81619/196527/79930/5049/51806/80184/1476/3304/2547/8673/10493/1075/53916/6282/114790/1778/10694/2512/3837/10890/5036/8621/5005/5315/23197/1991/10120/6317/7520/5717/9725/1604/10213/6278/5547/1522/2799/5768/1471/9588/29952/7415/4353/5701/6836/9342/8649/5265/3320/5686/388697/23593/391/175/5873/1088/57126/1143/23071/5878/2683/5646/945/7226/93100/47/79895/5906/89777/100049587/81567/10855/3687/84418/7097/5660/2212/1536/8987/10970/3689/961/2207/5724/2950/718/5223 317 Bunyavirus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 74/4506 75/10654 6.865554498005408e-27 1.472397380033775e-25 6.948941799600616e-26 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 74 Bunyavirus R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 110/4506 125/10654 1.0898515307766857e-26 2.301898536216212e-25 1.0863751303595354e-25 56955/4240/3270/9210/10272/2153/1511/7857/29106/91851/6696/51156/1435/265/11098/10130/2200/80341/375056/1114/720/10117/3956/3569/54972/2519/8720/7018/5340/10618/11167/813/5179/8074/51246/348/4924/4313/3484/102/8614/336/6694/4148/174/57104/721/2335/7466/116519/2266/51280/7076/2243/84141/3488/2147/8542/4221/351/4052/7184/56975/334/3912/338/64856/335/5611/197/3053/3895/5624/1000/54757/8404/255738/3913/652/57719/147111/2719/3487/3371/54587/401138/3486/7425/6383/3827/3490/5589/2621/3915/5768/1471/1462/10232/462/3698/5265/1758/258/11320/5954/213/10970/5034/1356/718 110 Bunyavirus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72/4506 73/10654 3.806899012626148e-26 7.920622721792314e-25 3.7381176479047016e-25 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/5716/701/5693/5721 72 Bunyavirus R-HSA-72764 Eukaryotic Translation Termination 87/4506 93/10654 5.864528250365754e-26 1.2022282913249796e-24 5.6738856911433375e-25 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/2935/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/2107/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/23708/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 87 Bunyavirus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 71/4506 72/10654 8.960146331483876e-26 1.7592174628293693e-24 8.302581849039914e-25 5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 71 Bunyavirus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 71/4506 72/10654 8.960146331483876e-26 1.7592174628293693e-24 8.302581849039914e-25 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 71 Bunyavirus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 71/4506 72/10654 8.960146331483876e-26 1.7592174628293693e-24 8.302581849039914e-25 5689/9134/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/990/5699/5702/8900/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/898/890/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/1017/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 71 Bunyavirus R-HSA-72202 Transport of Mature Transcript to Cytoplasm 80/4506 84/10654 1.9224974644698711e-25 3.722168702043056e-24 1.7566680048153064e-24 23165/8683/6431/84271/199746/348995/57122/23511/81608/65109/23279/23225/9877/9972/8021/55746/7919/53981/6432/8563/6430/56001/80145/10762/22794/9785/11338/29107/4116/79902/9883/51213/10250/26097/51362/1977/57187/6396/129401/79228/2733/84324/4928/5903/55706/7175/7884/6428/10212/55110/84321/6429/4927/10898/10569/9295/10482/51692/8086/9939/6426/22916/10921/81929/9631/29894/79023/23636/4686/8189/53371/7307/9688/9984/10189/9775/84248/6427/8480/55339 80 Bunyavirus R-HSA-68949 Orc1 removal from chromatin 70/4506 71/10654 2.1082391353584875e-25 4.025870348890043e-24 1.8999992207628763e-24 8454/5689/5682/143471/5705/5709/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/890/9861/6502/5698/5692/5713/4175/5710/5719/6233/4999/4172/5000/4173/5706/5714/5688/5687/5708/81620/5704/23595/7311/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 70 Bunyavirus R-HSA-2132295 MHC class II antigen presentation 107/4506 123/10654 4.596790828317702e-25 8.659360019830915e-24 4.086762827451728e-24 64837/162/11127/51807/10484/1174/347688/3798/1785/10381/7278/1780/3115/1509/8655/84516/3109/832/285643/3113/10112/972/7846/5476/3117/113457/9632/81027/6456/11004/3112/163/1759/3127/81930/51164/161/79861/3797/29127/3126/22872/3111/3796/89953/56992/83547/10376/10540/3835/147700/51128/1213/1211/9493/6396/1175/7879/140735/8907/3831/3120/1173/84617/11258/6712/1783/10382/10802/93661/821/55860/830/3123/3832/7277/160/10671/3122/1639/26052/26153/1062/347733/51143/9871/10383/24137/84790/84643/3125/22920/1075/7280/829/1778/114876/164/9371/3119/10120/112714/1781/10121/3799/375/10427 107 Bunyavirus R-HSA-5617833 Cilium Assembly 156/4506 201/10654 7.537954680030536e-25 1.4010545098616756e-23 6.6122409473952075e-24 55763/79738/79867/7531/11190/203068/11127/54801/51807/123016/85302/347688/79441/10381/5116/7278/5048/10576/22832/60412/8655/83658/6010/89891/54585/9702/132320/7846/7840/113457/11064/84902/81027/5518/55835/23332/166379/93323/79659/79861/3797/10575/1454/9321/10013/54806/91147/983/79959/8729/10376/10540/11336/117177/57545/26005/54930/54820/23322/378/56623/1453/9793/4218/140735/80173/582/84617/11258/22981/8636/54903/80776/3842/7532/55125/10382/6753/6991/8100/121441/7277/26146/585/9814/23354/146057/9738/1639/55722/4957/5566/7283/347733/22919/27077/22994/4867/1069/5577/10383/583/5347/84790/22948/80184/22897/22920/5108/261734/57787/7280/10806/9657/1778/55770/23265/115106/10694/22995/55559/9371/10142/10640/23059/51134/95681/79989/112714/7203/1781/80321/8766/79598/149371/10121/347240/84131/6950/55212/3320/79600/10733/4751/80254/26123/54536/9662/55142/92482/8195/129880/8481/27241/51259/55755 156 Bunyavirus R-HSA-2408557 Selenocysteine synthesis 86/4506 93/10654 1.022253802869596e-24 1.875028685789759e-23 8.84914995558861e-24 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/60678/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/79048/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 86 Bunyavirus R-HSA-8854518 AURKA Activation by TPX2 71/4506 73/10654 1.9190042615093575e-24 3.474145377329928e-23 1.6396140306812695e-23 7531/11190/203068/54801/79441/5116/5048/8655/6790/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/22974/3161/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 71 Bunyavirus R-HSA-5357801 Programmed Cell Death 143/4506 181/10654 2.879508773218181e-24 5.1461990126489034e-23 2.4287354699883446e-23 5689/2339/5682/4976/7531/55075/356/10971/10059/7533/2810/143471/5705/5709/1869/5695/8655/660/5711/836/5683/324/5699/5702/4001/3836/6709/6093/840/7159/26060/637/5062/5696/5691/7314/5718/2934/11035/22985/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/7082/5339/4836/5317/9861/28988/10134/999/5588/598/5698/10000/5692/708/5713/5710/3002/7157/5719/6233/5580/1613/8772/331/8717/317/140735/1828/5747/1029/572/7532/330/118/5706/1829/6774/5714/8428/5688/5687/1832/56616/5708/8837/8626/197259/208/5704/7311/7161/5694/3148/7529/5595/4000/5533/3837/1676/596/5684/5720/7186/51765/1499/10018/842/207/5690/5717/9491/355/10197/7099/9500/7316/10213/54205/115209/5715/5701/329/5685/5686/5534/4137/5716/581/5599/7431/5693/5721 143 Bunyavirus R-HSA-72766 Translation 207/4506 291/10654 6.147877557333078e-24 1.0832633987569165e-22 5.112433921491149e-23 6158/6138/5464/6227/6206/1965/6234/27335/6191/6128/6132/1917/6129/1915/64979/26284/9255/6176/55176/8668/6224/6146/6154/8662/26986/6202/64949/65003/64983/55052/6169/6175/219927/6218/6728/6173/64968/6167/116832/51069/6156/6143/1973/124995/28973/6139/6745/51067/64928/3921/8665/10667/65005/23478/6208/6170/92935/6203/10952/29093/6147/8666/6222/4528/8667/6727/7818/6184/79731/6183/58477/2935/6134/6747/6731/55699/6155/55157/10240/6729/6231/6142/7458/8663/23521/8894/1981/6185/6207/1977/6726/6233/28957/9801/51386/6188/26589/64965/9553/7284/200916/6122/1968/6230/8669/6194/2107/6166/124454/1938/1650/1983/6136/6125/1937/23395/10056/6232/6160/6748/51023/29927/1933/60559/6746/6193/6210/6229/6205/54148/28972/57038/140801/23438/6235/6181/740/1975/23471/55168/64951/7311/6223/25873/8664/63875/6730/23708/90701/9045/6187/6168/6157/6137/1974/55037/29074/51264/6144/6182/9349/57505/4736/51121/6159/56945/9521/6217/1936/6152/92399/51065/6141/10480/6123/28998/23480/25973/6164/8661/57176/9669/6209/1964/11224/6165/6130/6204/64969/51081/6228/54938/7965/55173/6124/2193/3646/6189/9789/6135/6201/6161/51649/54998/8892/6133/51021 207 Bunyavirus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 113/4506 134/10654 6.216719648533237e-24 1.0832633987569165e-22 5.112433921491149e-23 5295/8454/5689/3725/4893/5335/4790/5682/7321/143471/5705/5530/5709/5695/4792/3709/5711/5683/2534/5699/5702/2885/9846/3845/7334/3265/3551/5062/5696/5691/7314/5879/5718/8945/4773/5290/5700/122706/5707/5594/4214/23198/23118/10892/8517/5970/9861/5588/5698/5692/5713/5710/10454/5719/6233/7410/7409/3702/2353/3710/801/805/5170/6464/4772/3937/5706/6850/8915/5714/5688/5687/4067/5708/5602/695/7189/6654/5704/7311/5694/5058/6416/997/5595/1147/9402/5684/5720/6885/5690/5717/9491/6500/3708/10197/7316/10213/10768/7322/5715/5701/23291/5685/5686/5534/5609/5716/5296/5599/5693/5721/2207 113 Bunyavirus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 66/4506 67/10654 6.440237976710509e-24 1.1083570048807963e-22 5.230862554183325e-23 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 66 Bunyavirus R-HSA-109581 Apoptosis 140/4506 178/10654 1.9635582550018407e-23 3.3380490335031293e-22 1.5753837090836334e-22 5689/2339/5682/4976/7531/55075/356/10971/10059/7533/2810/143471/5705/5709/1869/5695/8655/660/5711/836/5683/324/5699/5702/4001/3836/6709/6093/840/7159/26060/637/5062/5696/5691/7314/5718/2934/22985/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/7082/5339/4836/5317/9861/28988/10134/999/5588/598/5698/10000/5692/708/5713/5710/3002/7157/5719/6233/5580/1613/8772/331/8717/317/140735/1828/5747/1029/572/7532/118/5706/1829/6774/5714/8428/5688/5687/1832/56616/5708/8837/8626/208/5704/7311/7161/5694/3148/7529/5595/4000/5533/3837/1676/596/5684/5720/7186/51765/1499/10018/842/207/5690/5717/9491/355/10197/7099/9500/7316/10213/54205/115209/5715/5701/329/5685/5686/5534/4137/5716/581/5599/7431/5693/5721 140 Bunyavirus R-HSA-195253 Degradation of beta-catenin by the destruction complex 77/4506 82/10654 2.1737540627701145e-23 3.6508592331343847e-22 1.7230136832356647e-22 8454/5689/5682/5526/1452/143471/5705/5709/9978/5695/5711/5683/324/5699/8312/5702/6932/5518/5696/5691/7314/5515/5718/51176/8945/5700/122706/5707/23198/5528/7091/83439/9861/5519/2932/5698/5692/5713/5710/5719/6233/7089/7090/5706/5714/6934/5688/5687/5708/5529/7088/5704/7311/5694/5516/5684/5720/1487/1499/5525/139285/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/3065/5527/5716/5693/5721 77 Bunyavirus R-HSA-380259 Loss of Nlp from mitotic centrosomes 68/4506 70/10654 2.39502562883603e-23 3.927842031291089e-22 1.8537350068390326e-22 7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 68 Bunyavirus R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 68/4506 70/10654 2.39502562883603e-23 3.927842031291089e-22 1.8537350068390326e-22 7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 68 Bunyavirus R-HSA-5663220 RHO GTPases Activate Formins 116/4506 140/10654 3.328679963226634e-23 5.395557986904567e-22 2.546419800509971e-22 55839/11130/71/6249/9735/5526/51807/9212/347688/388/147841/348995/10381/57122/7278/1780/23122/3688/5048/8655/23279/2491/7846/113457/1060/81027/11004/1855/9184/5518/23332/10726/81930/55746/5879/5515/79682/10403/79861/25936/1856/389/64105/332/5528/6714/79902/3796/5519/81565/91687/11243/10376/23002/83540/1857/7514/54820/1729/5217/6396/64946/9793/140735/84617/4928/5903/80776/1783/401541/10382/79172/7277/79980/6232/5501/9183/1062/699/347733/752/22919/5529/51143/998/10383/5347/387/60/84790/84643/7280/1778/5516/81929/54908/55143/5525/1058/991/79019/80152/1063/23421/55920/79023/112714/1781/4085/5216/81624/55166/79003/5527/701/23380 116 Bunyavirus R-HSA-202424 Downstream TCR signaling 88/4506 98/10654 5.334335249157593e-23 8.547199238305384e-22 4.033828833301265e-22 5295/8454/5689/4790/5682/7321/143471/5705/3115/5709/5695/4792/3113/5711/3117/5683/5699/5702/3127/7334/3551/5696/5691/7314/5718/8945/5290/5700/122706/5707/23198/23118/10892/8517/3126/5970/9861/5588/5698/5692/5713/5710/5719/6233/3932/3120/5170/3123/5706/3122/920/8915/5714/5688/5687/5708/7189/5704/7311/3125/5694/997/1147/5684/5720/6885/3119/5690/5717/9491/6500/10197/7316/10213/50852/7322/5715/5701/23291/915/5685/917/5686/5728/5716/5296/5693/5721 88 Bunyavirus R-HSA-9006925 Intracellular signaling by second messengers 213/4506 305/10654 6.033954029797266e-23 9.558331724474306e-22 4.5110302256259465e-22 5295/1912/2308/5689/374/3725/5335/5682/23035/1459/5526/9112/817/6045/7039/5578/5582/27327/80012/1460/143471/2064/5705/5709/5695/1457/1911/4734/3709/11060/5711/5928/5683/145957/2534/23512/5699/2444/3630/5702/192669/1107/8975/3654/9542/2885/2475/8660/5518/1386/4343/80351/5696/814/5691/7314/5879/5515/5718/818/23396/1839/5290/3667/6801/2065/23186/5700/3815/122706/5707/5567/2146/51564/5594/2069/84335/8074/7249/23198/57761/8395/2260/5528/6714/2099/9861/7101/81847/5519/2932/84733/5698/10000/5692/5713/5710/3066/7157/5613/5719/6233/5580/7409/3932/2931/3710/331/8726/8394/26523/7874/801/5781/57521/253260/28956/805/5170/3838/572/9219/8535/4303/5931/5706/6199/4233/8658/5714/10645/1108/2122/64223/5566/84254/10014/8503/5688/5159/5687/5708/3084/54815/5529/816/7189/208/5577/5704/10718/7311/1956/648/2549/5694/23466/53615/5595/5516/1147/27161/815/5684/8841/685/5720/2309/5468/5525/842/5978/10273/207/5690/5717/1027/9491/3708/10197/192670/4615/2100/7316/10213/1950/1026/50852/10768/5715/2261/5701/5576/5685/2255/8649/3164/5686/391/5728/6615/3065/2066/23028/5987/5527/5716/4254/5296/5581/5693/5721/4193 213 Bunyavirus R-HSA-983189 Kinesins 59/4506 59/10654 7.15613833080921e-23 1.1208603183312402e-21 5.289871622419582e-22 64837/11127/51807/347688/3798/10381/7278/285643/10112/64147/7846/113457/81027/11004/10749/81930/113220/79861/3797/29127/55605/3796/124602/55614/89953/56992/10376/3835/147700/3833/9493/3831/84617/9585/10382/3832/7277/23303/26153/1062/146909/347733/90990/23046/10383/24137/84790/84643/22920/7280/55582/9371/23095/112714/547/3834/55083/3799/221458 59 Bunyavirus R-HSA-68867 Assembly of the pre-replicative complex 66/4506 68/10654 1.285217752628991e-22 1.9906594968497927e-21 9.394866612785023e-22 5689/5682/143471/5705/5709/1869/4174/5695/84515/4998/5711/5683/990/5699/5702/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/9861/5698/5692/5713/4175/5710/5719/6233/4999/4172/5000/4173/5706/5714/51053/5688/5687/5708/81620/5704/23595/7311/5694/4176/5684/5720/5690/5717/9491/10197/7316/10213/4171/1871/5715/5701/5685/5686/5716/5693/5721 66 Bunyavirus R-HSA-1257604 PIP3 activates AKT signaling 189/4506 264/10654 1.7840963421706586e-22 2.7330003307537344e-21 1.2898325203662946e-21 5295/1912/2308/5689/374/3725/5682/23035/1459/5526/9112/6045/7039/27327/80012/1460/143471/2064/5705/5709/5695/1457/1911/4734/11060/5711/5928/5683/145957/2534/23512/5699/2444/3630/5702/192669/1107/8975/3654/9542/2885/2475/8660/5518/1386/4343/80351/5696/5691/7314/5879/5515/5718/23396/1839/5290/3667/6801/2065/23186/5700/3815/122706/5707/2146/51564/5594/2069/84335/8074/7249/23198/57761/8395/2260/5528/6714/2099/9861/7101/81847/5519/2932/84733/5698/10000/5692/5713/5710/3066/7157/5719/6233/7409/3932/2931/331/8726/8394/26523/7874/5781/57521/253260/28956/5170/572/9219/8535/4303/5931/5706/6199/4233/8658/5714/1108/2122/64223/10014/8503/5688/5159/5687/5708/3084/54815/5529/7189/208/5704/10718/7311/1956/648/2549/5694/23466/53615/5595/5516/1147/27161/5684/8841/685/5720/2309/5468/5525/842/5978/10273/207/5690/5717/1027/9491/10197/192670/4615/2100/7316/10213/1950/1026/50852/5715/2261/5701/5685/2255/8649/3164/5686/391/5728/6615/3065/2066/23028/5987/5527/5716/4254/5296/5693/5721/4193 189 Bunyavirus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 62/4506 63/10654 1.9564023041775715e-22 2.964374795677755e-21 1.3990291076784695e-21 5689/11065/5682/7321/8697/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/5707/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 62 Bunyavirus R-HSA-1169091 Activation of NF-kappaB in B cells 65/4506 67/10654 2.974731664272611e-22 4.4114637659532126e-21 2.081979048343093e-21 8454/5689/4790/5579/5682/143471/5705/5709/5695/4792/5711/5683/5699/5702/4794/3551/5696/5691/7314/5718/8945/5966/5700/122706/5707/23198/10892/8517/5970/9861/5698/5692/5713/5710/5719/6233/5706/8915/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/5690/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5716/5693/5721 65 Bunyavirus R-HSA-73856 RNA Polymerase II Transcription Termination 65/4506 67/10654 2.974731664272611e-22 4.4114637659532126e-21 2.081979048343093e-21 8683/6431/84271/51585/199746/81608/1477/65109/9877/7919/53981/6432/8563/6430/11051/80145/8106/22794/9785/11338/4116/1478/51213/10250/26097/51362/23283/6636/10914/57187/79228/84324/6635/7884/6428/10212/84967/6637/55110/84321/6429/10898/10569/9295/51692/9939/6426/22916/1479/10921/25888/79869/29894/4686/8189/10978/7307/9984/10189/6634/9775/84248/6427/55339/6628 65 Bunyavirus R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 71/4506 75/10654 3.05609503195555e-22 4.484417341627407e-21 2.116409301908276e-21 23165/8683/6431/84271/199746/348995/57122/23511/65109/23279/23225/9877/9972/8021/55746/7919/6432/8563/6430/56001/80145/10762/22794/9785/11338/29107/4116/79902/9883/51213/10250/26097/51362/57187/6396/129401/79228/2733/84324/4928/5903/55706/7175/6428/10212/55110/84321/6429/4927/10569/9295/10482/8086/9939/6426/22916/10921/81929/9631/79023/23636/4686/53371/7307/9688/9984/10189/9775/84248/6427/8480 71 Bunyavirus R-HSA-202403 TCR signaling 101/4506 119/10654 5.834713157224338e-22 8.472489730386174e-21 3.998569872001328e-21 5295/8454/5689/5335/4790/5682/7321/143471/5705/3115/5709/5695/4792/3113/5711/3117/5683/5699/5702/26191/3127/7334/3551/5062/5696/5691/7314/5718/8945/5290/5700/122706/5707/23198/23118/10892/8517/3126/5970/9861/5588/5698/5692/5713/1445/5710/5719/6233/3702/3932/3120/5170/3937/3123/5706/3122/920/8915/5714/5688/5687/5708/5063/7189/7535/5704/7311/3125/5694/5058/997/1147/55740/9402/5684/5720/6885/4690/3119/5690/5717/9491/6500/10197/7316/10213/50852/7322/5715/5701/23291/915/5685/917/5686/7408/5728/5716/5296/5693/5721 101 Bunyavirus R-HSA-5607764 CLEC7A (Dectin-1) signaling 89/4506 101/10654 6.531565927976356e-22 9.386600931545403e-21 4.429982316858625e-21 8454/5689/4790/5682/7321/9039/29108/143471/5705/5530/5709/5695/4792/3709/5711/5683/5699/5702/7334/3551/5696/5691/7314/5718/8945/4773/5700/122706/5707/23198/23118/10892/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/3710/801/4791/805/5170/4772/5706/6850/8915/5714/5688/5687/5708/7189/5704/7311/5971/5694/997/1147/5684/5720/6885/5690/5717/9491/6500/3708/10197/7316/10213/10768/7322/5715/5701/23291/5685/5686/5534/5716/5693/5721 89 Bunyavirus R-HSA-162906 HIV Infection 170/4506 233/10654 8.96941325786062e-22 1.2758532736181331e-20 6.021356913171737e-21 23165/5689/51652/2237/7852/162/5682/27243/6874/1174/348995/143471/57122/5705/55048/3981/5431/23511/5435/5709/9978/5433/5695/292/23279/5711/23327/29082/8732/23225/5683/2534/5699/5439/5702/3836/163/9972/8021/1794/11198/904/51497/5062/55746/5696/5691/7314/5879/5718/8945/51606/161/25978/5700/122706/5707/7518/23198/10015/5438/3978/10762/79720/4836/9861/79902/11168/9883/51510/5698/5692/5713/5710/5478/5719/6233/7514/1025/3932/6396/129401/1175/6829/8907/2957/60489/1173/4928/2963/5434/5903/55706/7175/5436/6878/4869/5706/160/293/920/4331/5714/4927/8148/2962/5688/5687/5708/128866/5901/8086/5704/7311/6880/6908/7251/5694/2547/2961/5432/22916/3837/6917/81929/5440/164/5684/8065/5720/9631/3159/5430/5690/7520/5717/9491/6500/6749/79023/5441/23636/10197/4686/7316/10213/6872/53371/3055/9688/8731/6879/9150/5715/9525/5701/2958/5437/5685/8815/5686/5716/9844/375/1022/5693/5721/8178/8480/291 170 Bunyavirus R-HSA-446203 Asparagine N-linked glycosylation 210/4506 304/10654 1.0497277097450839e-21 1.4781014418026737e-20 6.975861973319272e-21 6811/23256/374/4759/6711/11014/126003/10960/2153/2673/9761/51807/286/10484/7039/347688/5861/54187/811/10381/9945/7278/1780/9570/90411/8655/84516/832/3998/55738/7846/5476/113457/6400/51226/9382/375056/9632/3630/81027/55907/7991/6709/85365/51009/2720/79087/79090/10652/54732/51272/7314/51164/58485/1294/79861/9117/10342/9695/5700/10956/79139/55808/2801/91445/6184/377/55577/10466/2517/56052/22872/1315/81562/11253/8615/11316/80267/91949/8729/254263/23423/10376/1314/10540/6185/6233/51332/83696/51128/27095/6399/7109/23193/378/6396/79694/26286/1453/54344/8813/267/26958/10175/140735/10959/2348/84364/22820/84617/7841/22796/11258/6712/2890/1783/1650/6048/10382/10802/93661/821/55860/2157/830/7277/56886/64841/10671/9554/10206/84447/7264/966/84061/11196/1639/149111/10282/6710/8775/81876/4124/11015/347733/2923/51143/79748/51693/5537/7311/9871/10383/84790/55768/10945/10610/1075/7280/829/1778/9919/10113/51399/11070/25839/55291/51014/122553/7844/26984/83548/63908/112714/1604/282969/1781/7316/5589/57731/1522/10121/7415/2804/9527/57511/22870/5265/8774/29925/10972/51035/381/6708/4905/4245/11320/89866/2683/11236/9276/287/5887/375/84342/64689/288/10427/22818/372 210 Bunyavirus R-HSA-5678895 Defective CFTR causes cystic fibrosis 60/4506 61/10654 1.0758877235929756e-21 1.4997874866886078e-20 7.078208707848525e-21 5689/5682/143471/91319/5705/5709/5695/5711/5683/5699/6400/5702/51009/5696/5691/7314/5718/5700/122706/5707/10956/79139/91445/23198/9861/5698/5692/5713/5710/5719/10613/6233/27248/6048/5706/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 60 Bunyavirus R-HSA-69618 Mitotic Spindle Checkpoint 96/4506 112/10654 1.3745833465496506e-21 1.8971972129606068e-20 8.95377375292894e-21 55839/11130/11065/6249/9735/7321/5526/8697/9212/147841/348995/57122/1780/23122/5048/8655/23279/2491/1060/51529/29945/11004/51434/9184/5518/29882/23332/10726/81930/55746/996/5515/79682/10403/25936/64105/332/5528/51433/79902/3796/5519/81565/91687/119504/11243/7324/83540/64682/7514/54820/6396/64946/9793/140735/4928/5903/246184/80776/1783/401541/79172/79980/6232/8881/5501/9183/1062/699/22919/5529/51143/10393/25906/5347/84643/1778/5516/81929/54908/55143/5525/1058/991/79019/80152/1063/23421/55920/79023/1781/4085/55166/79003/5527/701 96 Bunyavirus R-HSA-2500257 Resolution of Sister Chromatid Cohesion 105/4506 126/10654 1.6625210609428982e-21 2.2721121166219608e-20 1.0723175057681232e-20 55839/11130/6249/9735/5526/51807/9212/347688/147841/348995/10381/57122/7278/1780/23122/5048/8655/23279/2491/7846/113457/1060/81027/11004/9184/5518/23332/10726/81930/55746/5515/79682/10403/79861/25936/55869/64105/332/5528/983/79902/3796/5519/81565/91687/11243/10376/83540/7514/54820/6396/64946/9793/140735/84617/4928/5903/80776/1783/401541/10382/79172/7277/9133/79980/6232/5885/891/5501/9183/1062/699/347733/22919/8243/5529/51143/10383/5347/84790/84643/7280/1778/5516/81929/54908/55143/5525/1058/991/79019/80152/1063/23421/55920/79023/10735/112714/1781/4085/55166/79003/9126/5527/701 105 Bunyavirus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 66/4506 69/10654 1.7350868207614126e-21 2.348263134117873e-20 1.1082567838281891e-20 23165/6782/573/7531/9530/348995/472/57122/3313/23511/3305/23279/91582/259217/23225/3309/9531/3306/27000/9972/23411/8021/6117/3312/55746/51182/3303/6118/5594/3308/10049/3337/10762/9261/79902/9883/2932/6396/129401/3297/4928/5903/55706/7175/4927/6119/57805/3310/7266/8086/3304/5595/81929/9631/116835/545/79023/23636/10808/53371/9532/9688/6767/22824/9529/8480 66 Bunyavirus R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 55/4506 55/10654 2.30275444215693e-21 3.086576627275731e-20 1.4567019497450217e-20 51807/347688/10381/7278/1780/3305/8655/84516/832/7846/113457/81027/3306/3312/51164/3303/79861/3337/10376/3301/10540/140735/84617/5241/11258/1783/10382/93661/10294/55860/830/7277/10671/1639/2908/347733/51143/3326/367/10383/84790/3304/7280/10728/829/1778/112714/4306/1781/2289/10121/3320/10963/55466/2288 55 Bunyavirus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 59/4506 60/10654 2.5215475739744913e-21 3.3160729416230576e-20 1.565012148693205e-20 8454/5689/9134/5682/5705/5709/5753/5695/5711/5683/5699/5702/8900/5696/5691/7314/5718/5700/5707/898/890/9861/6502/5698/5692/5713/595/5710/5719/6233/1163/1019/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/5690/5717/1027/9491/6500/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721 59 Bunyavirus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 59/4506 60/10654 2.5215475739744913e-21 3.3160729416230576e-20 1.565012148693205e-20 8454/5689/5682/9039/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/5970/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 59 Bunyavirus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 76/4506 83/10654 2.7192771818317148e-21 3.542684478012533e-20 1.671960884057867e-20 8454/5689/4893/4790/5579/5682/143471/5705/5530/5709/5695/4792/5711/5683/5699/5702/4794/3845/3265/3551/5696/5691/7314/5718/8945/4773/5966/5700/122706/5707/23198/10892/8517/5970/9861/5698/5692/5713/5710/2280/5478/5719/6233/801/805/4772/5706/8915/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/5690/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5534/5716/5693/5721 76 Bunyavirus R-HSA-204005 COPII-mediated vesicle transport 65/4506 68/10654 3.958086641655009e-21 5.1088636837658164e-20 2.4111151569535875e-20 6811/23256/374/126003/10960/2153/10484/7039/5861/9570/90411/3998/9632/79090/10652/58485/1294/9117/10342/2801/22872/81562/8615/254263/83696/51128/27095/6399/7109/6396/1453/10175/10959/2348/2890/10802/2157/9554/966/11196/149111/10282/8775/81876/79748/51693/5537/9871/1075/9919/10113/51399/55291/122553/26984/63908/1522/22870/5265/8774/10972/4905/89866/64689/10427 65 Bunyavirus R-HSA-983169 Class I MHC mediated antigen processing & presentation 245/4506 371/10654 5.8608192224523724e-21 7.418784585835298e-20 3.501276422371865e-20 8454/8773/5689/127544/11065/9666/55070/5682/7321/65264/10484/8697/9817/55176/9039/6478/811/143471/5705/57674/9690/8452/5709/9978/5695/4734/7337/84676/3106/5711/23327/51465/10616/5683/3309/25898/5699/7328/9632/7428/5702/22954/401036/83737/51529/10075/29945/79176/8924/51434/6468/10425/25793/23295/51666/90293/54461/29882/7334/92591/4591/3551/7332/5696/5691/9820/55658/7314/996/9354/5718/8945/51088/64410/10952/51320/5700/122706/5707/148581/23198/140462/6892/51130/8517/6477/7323/10517/22872/4008/84861/11059/51433/9861/55905/10134/6502/5698/27246/5692/5713/26190/79654/5710/9040/7324/5719/64682/6233/3685/26091/6047/51128/136371/6396/127247/1535/5930/26268/115290/51725/140459/3135/23352/26224/114088/653361/246184/9616/10802/6890/821/81559/2209/144699/5706/200845/79876/9554/8881/22888/29927/7317/80196/84078/5714/26272/64219/140458/5688/55336/5687/26270/89122/118424/5708/55008/2923/84727/695/90933/63891/9246/10393/5704/9870/4012/25847/51343/7311/9871/9320/26232/57520/5694/8673/92369/3105/997/84261/7325/57154/1147/5684/6737/8065/5720/84708/7319/54850/26046/991/10273/7320/5690/5717/25897/9491/6500/26259/10197/7099/154214/7336/4615/64750/51619/23480/23376/54778/142689/7316/10213/54926/222235/25831/7322/5715/5701/9341/23291/5685/5686/55521/55294/8453/80176/8139/126433/26267/142685/5716/90025/23194/80204/26234/27338/7097/1536/90678/5693/5721/51676/10427/642 245 Bunyavirus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 58/4506 59/10654 5.9073535798258104e-21 7.418784585835298e-20 3.501276422371865e-20 8454/5689/5682/9039/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 58 Bunyavirus R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 58/4506 59/10654 5.9073535798258104e-21 7.418784585835298e-20 3.501276422371865e-20 5689/5682/143471/5705/5709/5695/84515/4998/5711/5683/990/5699/5702/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/4999/5000/5706/5714/51053/5688/5687/5708/81620/5704/23595/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 58 Bunyavirus R-HSA-6807070 PTEN Regulation 113/4506 140/10654 8.028162984738761e-21 9.99219571493378e-20 4.715791226937713e-20 1912/5689/3725/5682/1459/9112/6045/27327/80012/1460/143471/5705/5709/5695/1457/1911/4734/11060/5711/5928/5683/23512/5699/2444/5702/192669/1107/8975/2475/1386/4343/80351/5696/5691/7314/5718/23186/5700/122706/5707/2146/51564/5594/23198/9861/7101/81847/84733/5698/10000/5692/5713/5710/3066/7157/5719/6233/331/8726/26523/7874/57521/28956/9219/8535/5931/5706/8658/5714/1108/2122/64223/10014/5688/5687/5708/54815/208/5704/7311/648/5694/23466/53615/5595/27161/5684/8841/5720/5468/5978/10273/207/5690/5717/9491/10197/192670/7316/10213/5715/5701/5685/8649/5686/5728/6615/3065/23028/5987/5716/5693/5721 113 Bunyavirus R-HSA-2408522 Selenoamino acid metabolism 99/4506 118/10654 8.766253227162403e-21 1.081429822890654e-19 5.103780407057758e-20 6158/6138/6227/6206/6234/6191/6128/6132/6129/9255/6176/6224/6146/6154/6202/6169/1491/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/7296/6203/6147/4143/191/6222/2936/27232/6134/60678/6155/6231/6142/9061/23521/6207/6233/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/102724560/140801/6235/6181/7311/6223/25873/9045/6187/9060/6168/6157/6137/6144/9349/4736/51121/6159/9521/6217/6152/51065/6141/6123/6164/79048/6209/11224/6165/6130/6204/6228/51540/7965/6124/6189/6135/6201/6161/6133 99 Bunyavirus R-HSA-72187 mRNA 3'-end processing 57/4506 58/10654 1.3833764956428007e-20 1.6916024867772493e-19 7.983474697846265e-20 8683/6431/84271/51585/199746/81608/1477/65109/9877/7919/53981/6432/8563/6430/11051/80145/8106/22794/9785/11338/4116/1478/51213/10250/26097/51362/23283/10914/57187/79228/84324/6428/10212/55110/84321/6429/10898/10569/9295/51692/9939/6426/22916/1479/10921/79869/29894/4686/8189/10978/7307/9984/10189/9775/84248/6427/55339 57 Bunyavirus R-HSA-8948751 Regulation of PTEN stability and activity 65/4506 69/10654 4.0081833731175814e-20 4.858615323587746e-19 2.2930110830192116e-19 5689/5682/1459/1460/143471/5705/5709/5695/1457/4734/11060/5711/5683/5699/2444/5702/8975/80351/5696/5691/7314/5718/5700/122706/5707/23198/9861/81847/5698/10000/5692/5713/5710/5719/6233/331/5706/8658/5714/5688/5687/5708/208/5704/7311/5694/5684/5720/10273/207/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5728/5987/5716/5693/5721 65 Bunyavirus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 55/4506 56/10654 7.576755178822156e-20 9.027347623314604e-19 4.2604336363147536e-19 5689/5682/26986/143471/5705/5709/5695/5711/5683/5699/5702/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/9861/5698/5692/5713/1981/5710/5719/6233/3315/5706/5714/5688/5687/5708/5704/7311/5694/3304/5684/5720/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 55 Bunyavirus R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 55/4506 56/10654 7.576755178822156e-20 9.027347623314604e-19 4.2604336363147536e-19 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/51009/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/9861/5698/5692/5713/5710/5719/6233/27248/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 55 Bunyavirus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 94/4506 112/10654 8.074197772696691e-20 9.538501436558633e-19 4.501671371931696e-19 5295/8454/5689/4893/4790/5579/5682/143471/5705/5530/5709/5695/4792/3709/5711/5683/2534/5699/5702/30011/2885/4794/3845/3265/3551/5696/5691/7314/6786/5718/8945/4773/5966/5700/122706/5707/23198/10892/8517/5970/9861/5698/5692/5713/5710/2280/5478/5719/6233/7409/3710/801/805/4772/5706/6850/8915/5714/5688/5687/4067/29760/5708/695/6654/5704/7311/5694/1147/5684/5720/6885/4690/640/5690/5717/9491/6500/3708/10197/7316/10213/10768/4793/5715/5701/23291/5685/5686/5534/974/5716/5693/5721 94 Bunyavirus R-HSA-69615 G1/S DNA Damage Checkpoints 64/4506 68/10654 9.004678242951513e-20 1.0548337370314628e-18 4.978260859659173e-19 5689/9134/5682/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/993/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/1111/5704/7311/5694/1017/5684/5720/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Bunyavirus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 76/4506 85/10654 9.283787346160566e-20 1.0784666300456526e-18 5.089795694166979e-19 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/1163/1019/5706/4331/5714/5688/5687/5708/1874/208/5704/55957/51343/7311/5694/1017/5684/994/5720/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1026/5715/5701/5685/5686/5716/1022/5693/5721 76 Bunyavirus R-HSA-1234174 Cellular response to hypoxia 69/4506 75/10654 9.931156654497174e-20 1.144134907137939e-18 5.39971544937863e-19 5689/5682/64344/7321/3091/143471/5705/5709/9978/5695/5711/1387/5683/5699/126374/25994/7428/5702/2056/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/405/112399/84962/5706/5714/5688/5687/5708/5704/7311/2034/55662/5694/5684/5720/7422/5690/5717/9491/10197/7316/10213/8994/7322/5715/5701/5685/5686/2033/8453/5716/54583/5693/5721 69 Bunyavirus R-HSA-5610780 Degradation of GLI1 by the proteasome 58/4506 60/10654 1.0409572774951316e-19 1.1702374555066238e-18 5.52290575920592e-19 8454/5689/5682/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/83737/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/8650/9861/5698/5692/5713/5710/5719/6233/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/2735/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 58 Bunyavirus R-HSA-5610783 Degradation of GLI2 by the proteasome 58/4506 60/10654 1.0409572774951316e-19 1.1702374555066238e-18 5.52290575920592e-19 8454/5689/5682/1452/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/9861/2932/5698/5692/5713/5710/5719/6233/5706/5714/5566/2736/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 58 Bunyavirus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 58/4506 60/10654 1.0409572774951316e-19 1.1702374555066238e-18 5.52290575920592e-19 8454/5689/5682/1452/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/2737/9861/2932/5698/5692/5713/5710/5719/6233/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 58 Bunyavirus R-HSA-3858494 Beta-catenin independent WNT signaling 115/4506 146/10654 1.4575590856352494e-19 1.62546989230043e-18 7.671363608606576e-19 2788/5689/5579/5682/5578/1212/5582/27327/143471/5705/2775/5530/5709/5695/3709/5711/5683/5699/2782/5702/192669/1855/6932/163/4343/5593/3845/5696/5691/4920/7314/5879/2787/5718/51176/161/5700/122706/5707/1856/23198/10681/83439/2792/9861/5698/5692/5713/2785/2783/23002/2784/5710/5719/6233/1857/1213/3710/1211/1175/26523/801/2791/805/1173/144165/4772/409/5706/160/5714/6934/5688/5687/5708/2786/5704/7311/387/5694/57154/27161/815/5684/5720/54331/6885/1499/59345/5690/5717/9491/50855/51764/94235/3708/10197/192670/64750/7316/10213/55970/5216/5715/5701/2793/5685/5686/5534/23513/5716/5693/5721/6259/2790 115 Bunyavirus R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 54/4506 55/10654 1.772024370726456e-19 1.945040923458803e-18 9.17957092170771e-19 8454/5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/26271/5706/5714/5688/5687/5708/5704/51343/7311/5694/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 54 Bunyavirus R-HSA-4641257 Degradation of AXIN 54/4506 55/10654 1.772024370726456e-19 1.945040923458803e-18 9.17957092170771e-19 5689/5682/143471/5705/5709/5695/5711/5683/5699/8312/5702/80351/5696/5691/7314/5718/5700/122706/5707/23198/9861/81847/5698/5692/5713/5710/8313/5719/6233/5706/8658/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/5716/5693/5721 54 Bunyavirus R-HSA-5387390 Hh mutants abrogate ligand secretion 57/4506 59/10654 2.397364891895894e-19 2.610880202580372e-18 1.2321982380221496e-18 5689/5682/143471/5705/5709/5695/3549/5711/5683/5699/6400/5702/51009/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/50846/9861/5698/5692/5713/5710/5719/6233/27248/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 57 Bunyavirus R-HSA-8878159 Transcriptional regulation by RUNX3 83/4506 96/10654 2.4248163352707416e-19 2.6203054041607858e-018 1.2366464378165757e-18 5689/6046/5682/5705/6696/5709/5695/9759/10413/4609/4089/22938/5711/1387/7005/4088/5683/5699/5702/6932/7040/3845/5696/5691/7314/5718/8463/51176/2648/5700/5707/3280/83439/6714/9861/8850/5698/5692/5713/595/5710/7157/5719/6233/1029/864/5706/5714/6934/5688/5687/5708/5704/7311/5694/4851/3676/57154/5684/5720/2309/1499/10018/5690/5717/9491/10197/64750/7316/10213/1026/5715/5701/5685/5686/2033/861/5716/25937/3516/5693/5721/4193 83 Bunyavirus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 53/4506 54/10654 4.142473336816724e-19 4.442006024248087e-18 2.0963933890772893e-18 8454/5689/5682/143471/5705/5709/9978/5695/6790/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/23194/5693/5721 53 Bunyavirus R-HSA-69202 Cyclin E associated events during G1/S transition 74/4506 83/10654 4.2271788123341205e-19 4.498234552972339e-18 2.1229302994847935e-18 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/1163/1019/5706/4331/5714/5688/5687/5708/1874/208/5704/55957/7311/5694/1017/5684/5720/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1026/5715/5701/5685/5686/5716/1022/5693/5721 74 Bunyavirus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 62/4506 66/10654 4.530818385519834e-19 4.713403604040783e-18 2.2244787831499582e-18 5689/5682/64344/7321/3091/143471/5705/5709/9978/5695/5711/5683/5699/126374/7428/5702/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/112399/84962/5706/5714/5688/5687/5708/5704/7311/2034/5694/5684/5720/5690/5717/9491/10197/7316/10213/8994/7322/5715/5701/5685/5686/8453/5716/54583/5693/5721 62 Bunyavirus R-HSA-69563 p53-Dependent G1 DNA Damage Response 62/4506 66/10654 4.530818385519834e-19 4.713403604040783e-18 2.2244787831499582e-18 5689/9134/5682/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 62 Bunyavirus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 62/4506 66/10654 4.530818385519834e-19 4.713403604040783e-18 2.2244787831499582e-18 5689/9134/5682/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 62 Bunyavirus R-HSA-195258 RHO GTPase Effectors 217/4506 327/10654 4.5925433681950665e-19 4.742226263158461e-18 2.2380815634478887e-18 55839/11130/64837/71/6249/5579/9735/7531/5526/51807/10971/5578/9212/347688/3798/388/7533/2810/147841/348995/10381/57122/6280/7278/1780/23122/3688/5048/8655/10094/23279/1432/2017/2491/7846/113457/79784/9475/1060/81027/4628/11004/8976/1855/2885/6093/9184/8826/10499/5518/23332/3071/10726/81930/5062/55746/5879/5515/26999/25/79682/1072/10403/79861/4638/25936/4659/10093/1856/10006/4771/389/5594/64105/7534/332/5528/6714/79902/3796/5519/81565/999/89953/10810/91687/11243/10376/23002/11113/83540/5580/9055/1857/128239/23191/7514/147700/54820/1729/5217/6396/1535/801/64946/9793/30849/10109/5586/140735/5500/10787/4221/805/3831/5170/84617/4928/5590/5903/653361/5747/80776/1783/401541/2316/7532/10382/10627/79172/7277/79980/6232/5501/10152/6279/10092/9183/10163/1062/699/347733/752/22919/55845/5063/3895/5529/51143/998/695/10788/10097/367/10383/5347/387/60/84790/84643/5058/4660/7280/4629/7529/5595/1778/5516/81929/3984/54908/55143/1495/1499/5525/4690/1058/991/79019/4627/80152/10458/1063/3985/54763/1027/1080/23421/55920/79023/112714/1781/10398/4085/5289/5585/5216/10552/81624/55166/8936/4637/995/79003/391/23028/5527/10096/701/23380/9928/29941/3799/103910/5300/10095/1536 217 Bunyavirus R-HSA-1852241 Organelle biogenesis and maintenance 200/4506 296/10654 5.369601761849934e-19 5.503841805896183e-18 2.5975240721023294e-18 55763/5563/79738/79867/55735/79718/7531/11190/203068/11127/54801/51807/123016/85302/347688/79441/10381/5116/7278/3313/5048/10576/22832/10989/60412/8655/83658/6010/89891/54585/9702/132320/1432/1387/25813/7846/7840/113457/2101/11064/84902/81027/10499/23054/5518/1386/55835/3054/23332/7019/166379/93323/814/79659/79861/3797/10575/1454/9321/10013/54806/5465/91147/54927/983/64784/79959/2747/6604/8729/10376/10540/11336/117177/57545/55902/26005/54930/54820/23322/6742/378/56623/1453/801/9793/4218/140735/805/80173/582/84617/11258/22981/8636/54903/80776/79135/3842/3418/7532/55125/10382/6753/23410/6991/8100/121441/7277/26146/585/9814/4209/23354/2553/146057/9738/1639/55722/4957/5566/5571/7283/347733/22919/27077/22994/4867/6648/1069/10651/5577/10383/583/5347/84790/22948/80184/22897/5564/23373/22920/5108/261734/2746/57787/7280/10806/9657/1778/55770/23265/139322/115106/10694/22995/55559/8841/9371/10142/10640/23059/51134/95681/200186/79989/112714/7203/1781/80321/8766/9611/79598/54205/149371/10121/347240/84131/6950/55212/3320/79600/10733/6256/4751/10498/80254/26123/54536/9662/55142/92482/8195/129880/8648/8481/27241/51259/55755/10891 200 Bunyavirus R-HSA-72649 Translation initiation complex formation 56/4506 58/10654 5.517360719170112e-19 5.573333943857345e-18 2.6303207089865145e-18 6227/6206/1965/6234/27335/6191/8668/6224/8662/26986/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1968/6230/8669/6194/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 56 Bunyavirus R-HSA-72702 Ribosomal scanning and start codon recognition 56/4506 58/10654 5.517360719170112e-19 5.573333943857345e-18 2.6303207089865145e-18 6227/6206/1965/6234/27335/6191/8668/6224/8662/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1968/6230/8669/6194/1983/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 56 Bunyavirus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 207/4506 309/10654 5.911094621694258e-19 5.928104965929349e-18 2.7977539860347684e-18 8454/5689/127544/11065/9666/55070/5682/7321/65264/8697/9817/9039/6478/143471/5705/57674/9690/8452/5709/9978/5695/4734/7337/84676/5711/23327/51465/10616/5683/25898/5699/7328/7428/5702/22954/401036/83737/51529/10075/29945/79176/8924/51434/6468/10425/25793/23295/51666/90293/54461/29882/7334/92591/4591/7332/5696/5691/9820/55658/7314/996/9354/5718/8945/51088/64410/51320/5700/122706/5707/148581/23198/140462/51130/6477/7323/10517/4008/84861/11059/51433/9861/55905/6502/5698/27246/5692/5713/26190/79654/5710/9040/7324/5719/64682/6233/26091/6047/136371/127247/5930/26268/115290/51725/140459/23352/26224/114088/246184/9616/81559/144699/5706/200845/79876/8881/22888/7317/80196/84078/5714/26272/64219/140458/5688/55336/5687/26270/89122/118424/5708/55008/84727/90933/63891/9246/10393/5704/9870/4012/25847/51343/7311/9320/26232/57520/5694/92369/997/84261/7325/57154/5684/6737/8065/5720/84708/7319/54850/26046/991/10273/7320/5690/5717/25897/9491/6500/26259/10197/154214/7336/64750/51619/23376/54778/142689/7316/10213/54926/222235/25831/7322/5715/5701/23291/5685/5686/55521/55294/8453/80176/8139/126433/26267/142685/5716/90025/23194/80204/26234/27338/90678/5693/5721/51676/642 207 Bunyavirus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 77/4506 88/10654 1.0402121882827615e-18 1.035754136047264e-17 4.888215170501699e-18 5393/5689/5682/5578/26986/143471/5705/5709/5695/5711/1432/5683/5699/5702/8021/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/7534/9261/9861/5698/5692/5713/1981/5710/5719/6233/5580/7514/8570/23016/1994/3842/3315/5706/7538/5714/5688/5687/5708/5704/7311/5694/56915/3304/6418/167227/7529/22894/5684/5720/207/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/55802/5716/54464/5693/54512/5721 77 Bunyavirus R-HSA-4641258 Degradation of DVL 55/4506 57/10654 1.2688669158205948e-18 1.2456341413055698e-17 5.878738490643972e-18 5689/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/1855/5696/5691/7314/5718/5700/122706/5707/1856/23198/59349/9861/5698/5692/5713/5710/5719/6233/1857/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/23072/5693/5721 55 Bunyavirus R-HSA-69541 Stabilization of p53 55/4506 57/10654 1.2688669158205948e-18 1.2456341413055698e-17 5.878738490643972e-18 5689/5682/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/51230/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721/4193 55 Bunyavirus R-HSA-3700989 Transcriptional Regulation by TP53 236/4506 365/10654 1.754734339610164e-18 1.7105592093822158e-17 8.072940465633808e-18 5563/3725/9134/4436/64769/5892/9156/7531/1459/79370/7486/6874/10971/9997/9212/5982/27327/7295/7533/2810/55367/1460/11200/472/5431/7001/639/5435/5433/1869/84289/1457/6790/6341/25904/29117/4194/5928/1432/1387/4683/56950/51499/84126/5439/192669/1107/8900/2475/672/51204/5518/1386/55835/4343/6117/11198/7159/57472/904/144455/85456/51497/51230/637/7296/7314/5515/9377/23774/6118/2176/1329/7027/6446/2936/7249/898/117584/27244/7534/332/5438/1351/890/10769/983/1643/9656/5519/2821/2177/10000/5985/7994/54541/3066/7157/5984/6233/1121/1025/2353/604/10419/50484/9167/6829/26523/7874/317/2744/5884/5810/57521/26155/26013/253260/28956/5170/2963/5434/83667/1029/9219/8445/7532/5436/1345/204851/6878/4869/5931/4850/4292/580/11073/891/84987/80196/4331/641/5111/1108/8148/64223/2962/6119/147923/3364/5571/10524/4848/23019/1616/6794/54815/1874/10128/25824/1111/55215/8626/208/7311/7161/5562/6880/6908/5983/1340/4697/5564/1020/53615/10397/5432/7248/7529/5516/1017/27161/9891/6917/5440/8621/5883/5430/10111/8793/207/22974/835/4849/1027/3486/355/6749/545/5441/192670/9337/7316/6872/2539/1026/54205/5395/6879/9150/112858/143686/5437/1350/9099/8649/2033/995/5728/3065/91875/10498/5527/1349/5932/8851/5300/581/1327/3276/5052/133746/1022/8178/10919/4193 236 Bunyavirus R-HSA-4420097 VEGFA-VEGFR2 Pathway 84/4506 99/10654 1.8624295380364116e-18 1.802935261126915e-17 8.508906880648811e-18 5295/4893/857/5335/71/5579/5578/3709/1432/2534/9475/3690/5603/2475/6093/9564/3845/3265/3071/8877/5062/5829/5879/26999/5290/5567/10006/57761/5921/1500/9261/6714/10810/10000/3728/7410/5580/7409/23191/3685/3791/3710/1535/801/10787/253260/805/5170/5590/653361/6461/5747/3315/1793/10152/64223/5566/10163/55845/5063/998/208/2185/387/60/5058/63916/558/1495/1499/4690/207/7422/10458/3708/9047/10768/8936/3320/4846/1398/9844/5296/1536 84 Bunyavirus R-HSA-180534 Vpu mediated degradation of CD4 51/4506 52/10654 2.260631226483258e-18 2.114979818602457e-17 9.981593193585561e-18 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/920/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Bunyavirus R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 51/4506 52/10654 2.260631226483258e-18 2.114979818602457e-17 9.981593193585561e-18 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Bunyavirus R-HSA-69610 p53-Independent DNA Damage Response 51/4506 52/10654 2.260631226483258e-18 2.114979818602457e-17 9.981593193585561e-18 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Bunyavirus R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 51/4506 52/10654 2.260631226483258e-18 2.114979818602457e-17 9.981593193585561e-18 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Bunyavirus R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 51/4506 52/10654 2.260631226483258e-18 2.114979818602457e-17 9.981593193585561e-18 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/2932/5698/5692/5713/595/5710/5719/6233/1019/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Bunyavirus R-HSA-8951664 Neddylation 164/4506 234/10654 3.58619057756631e-18 3.332766443418291e-17 1.5728906041957502e-17 8454/5689/5682/64344/80344/55884/7321/4738/9817/9039/5929/3091/143471/5705/8452/5709/9978/5695/10980/5711/7347/5683/5699/79269/10987/7428/5702/401036/79176/6468/26094/25793/51666/90293/54461/92591/5696/5691/9820/7314/51514/5718/54165/8945/51088/64410/23363/23038/5700/122706/5707/23198/140462/55827/51130/332/7323/9306/10517/50717/4008/84861/79016/1643/9861/6502/90864/55832/5698/5692/10920/5713/26190/10238/5710/9040/5719/6233/83987/136371/8835/127247/26268/115290/54951/51725/140459/10537/8451/26224/9616/5931/144699/5706/200845/8450/84078/5714/26272/140458/5688/55336/5687/26270/1161/5708/1642/84727/5704/2873/7311/2034/8533/26232/51667/5694/51122/92369/84261/150684/51138/9318/5684/8065/5720/11091/25879/54850/5690/5717/9491/6500/28952/26259/10197/142689/7316/10213/64708/222235/7322/5715/5701/23291/170622/5685/5686/55294/8453/80176/8139/126433/26043/26267/142685/5716/23194/80204/26234/8816/5693/5721/51676/50813 164 Bunyavirus R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 50/4506 51/10654 5.277138816712578e-18 4.871742722183665e-17 2.29920652523204e-17 5689/5682/143471/5705/5709/5695/5711/4946/5683/5699/5702/5696/5691/5718/1728/51582/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/5706/4947/5714/5688/5687/5708/4953/5704/5694/5684/5720/5690/51686/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 50 Bunyavirus R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 56/4506 59/10654 6.375728282828776e-18 5.847213964646916e-17 2.759577684742372e-17 6227/6206/1965/6234/27335/6191/8668/6224/8662/26986/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1968/6230/8669/6194/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 56 Bunyavirus R-HSA-8941858 Regulation of RUNX3 expression and activity 53/4506 55/10654 6.695937093820947e-18 6.100742685481307e-17 2.879229916503676e-17 5689/5682/5705/5709/5695/5711/5683/5699/5702/7040/5696/5691/7314/5718/5700/5707/6714/9861/5698/5692/5713/5710/5719/6233/1029/864/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/2033/5716/5693/5721/4193 53 Bunyavirus R-HSA-5621481 C-type lectin receptors (CLRs) 110/4506 142/10654 8.936501732402016e-18 8.089274944784682e-17 3.817712633459508e-17 8454/5689/9252/4893/4790/5682/7321/9039/29108/143471/5705/5530/5709/5695/4792/3709/5711/1387/5683/2534/5699/5702/5894/3845/7334/3265/3551/5062/5696/5691/7314/5718/8945/4773/5700/122706/5707/5567/4582/23198/23118/10892/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/3710/801/4791/805/5170/4772/338339/3384/5706/56667/6850/8915/5714/5566/170482/5688/5687/4067/5708/5063/7189/5704/7311/5971/5694/5058/997/1147/5684/5720/6885/5690/5717/9491/6500/3708/10197/7316/10213/94025/10768/7322/5715/5701/23291/5685/5686/2033/5534/5716/5693/5721/2207 110 Bunyavirus R-HSA-2871837 FCERI mediated NF-kB activation 72/4506 82/10654 9.206259939737216e-18 8.279694423221729e-17 3.907580619582859e-17 8454/5689/4790/5682/7321/143471/5705/5709/5695/4792/5711/5683/5699/5702/7334/3551/5696/5691/7314/5718/8945/5700/122706/5707/23198/23118/10892/8517/5970/9861/5588/5698/5692/5713/5710/10454/5719/6233/5170/5706/8915/5714/5688/5687/4067/5708/7189/5704/7311/5694/997/1147/5684/5720/6885/5690/5717/9491/6500/10197/7316/10213/7322/5715/5701/23291/5685/5686/5716/5693/5721/2207 72 Bunyavirus R-HSA-8878166 Transcriptional regulation by RUNX2 97/4506 121/10654 1.146656927995121e-17 1.0246408702725634e-16 4.8357663967405585e-17 8454/8493/5689/7291/5682/5925/143471/5705/5709/9978/5695/9759/10413/4089/3549/5711/5683/2101/5699/5702/5696/5691/7314/5718/25/5700/122706/5707/5594/3280/23198/10013/2737/11059/983/6714/2099/9861/2932/6502/5698/10000/5692/5713/595/5710/5719/6233/7525/10432/1019/3958/5706/891/5714/6772/2736/5688/5687/2908/5708/208/5704/7311/367/1750/5694/5595/57154/5684/8841/5720/23462/10273/207/5690/5717/9491/6500/4086/59269/10197/7316/10213/1026/5715/5701/5685/5686/55294/861/5716/25937/581/5693/5721/10891 97 Bunyavirus R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 49/4506 50/10654 1.2312564469948354e-17 1.0932302465673889e-16 5.159472204973331e-17 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 49 Bunyavirus R-HSA-9604323 Negative regulation of NOTCH4 signaling 52/4506 54/10654 1.536393558188011e-17 1.3555269747557515e-16 6.397374909177262e-17 8454/5689/5682/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/5707/7534/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/4855/5704/7311/5694/5684/5720/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721 52 Bunyavirus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 289/4506 473/10654 3.105215845872322e-17 2.7224345214754817e-16 1.2848460136843438e-16 5295/374/9252/4893/857/5335/71/5579/5770/26469/7039/5578/1785/51741/23385/2064/535/54845/5431/8829/6696/5435/3688/5433/5753/4734/3709/10413/5605/3910/5898/1432/3908/3717/145957/2534/9475/3690/5439/5603/3630/6456/83737/7072/4145/9542/30011/2885/2475/8660/6093/163/7073/6196/9846/1759/5518/9564/6197/3845/3265/1399/3071/8877/5062/4486/51231/5829/7314/5879/5515/5607/54106/26999/51606/1839/3918/161/5290/3667/4485/2065/5340/526/3815/5567/10006/537/3911/2060/5594/2069/8074/284217/9101/23118/57761/5921/6778/2260/5438/348/5528/9306/1500/3185/11059/102/9261/6714/2099/5519/5598/4670/4914/529/10810/10000/9146/2335/64759/6195/3909/3728/8471/1445/533/84951/3925/6233/7525/7410/5580/2324/7409/23191/3685/3932/1213/3791/1729/3710/1211/29924/1535/6777/1175/523/801/200734/5781/30849/5663/2554/5725/1291/10787/253260/805/5170/1173/2963/5434/5800/5590/6464/85440/653361/5241/6461/5747/5782/5436/2322/7074/3315/2241/382/160/3912/1793/673/527/6774/4233/10152/6772/26052/64223/5566/5802/2962/8503/10163/5159/4067/3084/55845/5063/5771/1111/998/3913/80004/208/6654/10718/7311/2185/387/1956/60/2549/5058/1020/5432/3480/22916/11140/53916/4916/7529/63916/5595/5516/1845/9402/5440/8065/685/23543/26018/558/4915/1495/5604/1499/4690/5430/10048/10273/207/7422/10458/3178/10817/3708/5441/58513/4686/7316/1950/9611/9047/5289/57498/3915/10768/8936/3673/2261/867/5437/2255/3320/4846/4803/2066/3914/1398/3187/5774/9844/5906/4254/8851/5296/5581/581/10076/7059/1536/7057/10319/10254/161742/9296/2887/2242 289 Bunyavirus R-HSA-169911 Regulation of Apoptosis 51/4506 53/10654 3.5224270480737854e-17 3.0689145656342857e-16 1.4483663848987607e-16 5689/5682/4976/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/115209/5715/5701/5685/5686/5716/5693/5721 51 Bunyavirus R-HSA-8939902 Regulation of RUNX2 expression and activity 65/4506 73/10654 7.406252753273812e-17 6.412618843517823e-16 3.026419072112542e-16 8454/5689/7291/5682/143471/5705/5709/9978/5695/5711/5683/2101/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/11059/2099/9861/2932/6502/5698/5692/5713/5710/5719/6233/5706/5714/6772/5688/5687/2908/5708/5704/7311/1750/5694/57154/5684/5720/10273/5690/5717/9491/6500/59269/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721/10891 65 Bunyavirus R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/4506 52/10654 8.068982857244417e-17 6.943309940122665e-16 3.276877378673009e-16 5689/5682/143471/472/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Bunyavirus R-HSA-141424 Amplification of signal from the kinetochores 80/4506 96/10654 1.0973716801443663e-16 9.327659281227113e-16 4.4021649556497367e-16 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/8655/23279/2491/1060/11004/9184/5518/23332/10726/81930/55746/5515/79682/10403/25936/64105/332/5528/79902/3796/5519/81565/91687/11243/83540/7514/54820/6396/64946/9793/140735/4928/5903/80776/1783/401541/79172/79980/6232/5501/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/81929/54908/55143/5525/1058/991/79019/80152/1063/23421/55920/79023/1781/4085/55166/79003/5527/701 80 Bunyavirus R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 80/4506 96/10654 1.0973716801443663e-16 9.327659281227113e-16 4.4021649556497367e-16 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/8655/23279/2491/1060/11004/9184/5518/23332/10726/81930/55746/5515/79682/10403/25936/64105/332/5528/79902/3796/5519/81565/91687/11243/83540/7514/54820/6396/64946/9793/140735/4928/5903/80776/1783/401541/79172/79980/6232/5501/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/81929/54908/55143/5525/1058/991/79019/80152/1063/23421/55920/79023/1781/4085/55166/79003/5527/701 80 Bunyavirus R-HSA-1169408 ISG15 antiviral mechanism 64/4506 72/10654 1.573298671280304e-16 1.3291989986452994e-15 6.273120698884785e-16 3839/23165/5335/348995/57122/11274/23511/4734/23279/23225/1973/3836/4599/9972/8021/7334/55746/7314/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/1977/6233/5610/6396/129401/4928/3838/5903/55706/7175/3841/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/1974/5595/3837/81929/9631/79023/23636/7316/53371/9688/5300/9775/5495/8480 64 Bunyavirus R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 49/4506 51/10654 1.846804929742233e-16 1.5508711277473932e-15 7.319296646093188e-16 6227/6206/1965/6234/27335/6191/8668/6224/8662/6202/6218/3921/8665/6208/6203/8666/6222/8667/6231/8663/8894/6207/6233/51386/6188/1968/6230/8669/6194/6232/6193/6210/6229/6205/6235/6223/8664/6187/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 49 Bunyavirus R-HSA-5358346 Hedgehog ligand biogenesis 59/4506 65/10654 2.4276032973817595e-16 2.026394608712678e-15 9.563517559808384e-16 5689/5682/143471/5705/5709/5695/3549/5711/5683/5699/6400/5702/51009/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/50846/9861/5698/5692/5713/5710/5719/6233/27248/5706/84447/5714/5688/5687/5708/5704/7311/147111/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721/5034 59 Bunyavirus R-HSA-5687128 MAPK6/MAPK4 signaling 75/4506 89/10654 2.861060688716663e-16 2.3739991667089453e-15 1.1204028386265128e-15 2308/5689/3725/5682/27327/143471/5705/5709/5695/4609/5711/5683/5699/5702/192669/4343/5062/5696/5691/7314/5879/5718/5700/122706/5707/5567/23198/3337/983/9861/5698/5692/5713/5710/5719/6233/7514/26523/3315/5706/5597/5714/5566/5688/5687/5708/5063/998/5704/7311/5694/5058/27161/5684/5720/2309/10642/5690/5717/9491/10197/192670/5596/7316/10213/5715/5701/5685/5686/8556/5716/5896/8202/5693/5721 75 Bunyavirus R-HSA-180585 Vif-mediated degradation of APOBEC3G 51/4506 54/10654 3.7284996376131546e-16 3.0754606478300223e-15 1.4514557916588115e-15 5689/5682/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/60489/5706/5714/5688/5687/5708/5704/7311/5694/5684/8065/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Bunyavirus R-HSA-194138 Signaling by VEGF 86/4506 107/10654 6.111829691482501e-16 5.0117003470156506e-015 2.3652591685303796e-15 5295/4893/857/5335/71/5579/5578/8829/3709/1432/2534/9475/3690/5603/2475/6093/9564/3845/3265/3071/8877/5062/5829/5879/26999/5290/5567/10006/57761/5921/1500/9261/6714/10810/10000/3728/7410/5580/2324/7409/23191/3685/3791/3710/1535/801/10787/253260/805/5170/5590/653361/6461/5747/3315/1793/10152/64223/5566/10163/55845/5063/998/208/2185/387/60/5058/63916/558/1495/1499/4690/207/7422/10458/3708/9047/10768/8936/3320/4846/1398/9844/5296/1536 86 Bunyavirus R-HSA-69481 G2/M Checkpoints 122/4506 168/10654 1.0170664455004437e-15 8.291173245775548e-15 3.912998020546491e-15 5689/5682/9156/7531/7486/10971/5982/7533/2810/11200/143471/472/5705/5709/4174/5695/84515/4998/5711/4683/10926/5683/990/165918/84126/5699/5702/8924/55388/672/6117/7334/5001/7465/5696/5691/7314/5718/6118/23594/5700/122706/5707/51588/51720/23198/63967/7534/993/983/9861/9656/5698/5692/5985/5713/4175/5710/7157/5984/5719/6233/7158/5884/5810/4999/4172/5000/8318/51512/7532/4173/5706/9133/580/11073/891/641/5714/6119/3364/10524/5688/5687/5708/1111/5704/23595/7311/5983/5694/4176/7529/1017/5684/5720/5883/10111/8317/5690/5717/9491/545/10197/7336/29086/7316/10213/4171/5715/9088/7341/5701/5685/5686/995/5716/5932/9025/79184/5693/5721 122 Bunyavirus R-HSA-5696398 Nucleotide Excision Repair 88/4506 111/10654 1.3642295470674693e-15 1.105660458495379e-14 5.2181362724428915e-15 2074/10445/5982/6613/5431/5435/9978/5433/85015/10980/5439/10987/6117/7334/7314/6118/83444/86/5438/3978/1643/29844/5985/10920/5984/54891/6233/93973/8607/7874/5424/5886/8451/8554/10450/5434/5436/7515/54107/8450/4331/5425/5111/6119/5427/1161/1642/142/125476/1069/7329/2873/7311/3980/60/8533/5983/10038/5432/51138/7528/56655/9318/6917/5440/27339/5430/5441/7336/54778/7316/64708/5426/283899/7341/4798/5437/79913/54617/2033/56949/5887/9716/5981/1022/8178/50813/7508 88 Bunyavirus R-HSA-5683057 MAPK family signaling cascades 191/4506 294/10654 1.7349416724301681e-15 1.3979819025246556e-14 6.597739855606055e-15 2308/5689/374/3725/4893/6711/71/5682/5526/817/84292/7039/27327/143471/2064/5705/8452/4684/5709/9978/5695/1852/5605/4609/5037/5711/3558/3717/2244/5683/145957/2534/3690/408/5699/5702/192669/4296/5894/9542/2885/6709/8660/8826/5518/4140/4343/3845/3265/4763/3569/5062/5696/5691/7314/5879/5515/5718/818/1839/3667/2065/5700/3815/122706/5707/5567/8844/7094/5594/2069/8074/23198/7414/5921/3337/2260/5528/983/3718/6714/9861/5519/5698/5692/5713/2335/80824/1445/5710/5719/2906/6233/51332/2266/7514/2243/1843/26523/369/801/200734/7297/5781/28956/805/6464/6712/5747/283455/2322/3315/409/5706/673/4233/5597/84078/5714/64926/5566/6710/5688/5159/5687/5708/3084/5063/5529/816/998/9693/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/5058/7529/5595/5516/5786/27161/815/5684/685/5720/2309/5604/5525/10642/10048/5690/5717/9491/10817/10197/192670/5596/7316/10213/1950/3560/57731/5715/2261/5701/5685/2255/8649/5686/2066/6708/8556/5979/5527/5716/5906/4254/5896/399473/8202/5693/5721/5245/161742 191 Bunyavirus R-HSA-1236974 ER-Phagosome pathway 70/4506 83/10654 2.625261165848233e-15 2.1032264742485267e-14 9.926123585330586e-15 8773/5689/5682/55176/811/143471/5705/5709/5695/3106/5711/5683/5699/5702/3551/5696/5691/7314/5718/10952/5700/122706/5707/23198/6892/8517/9861/5698/5692/5713/5710/5719/6233/3135/6890/5706/9554/29927/5714/5688/5687/5708/2923/695/5704/7311/5694/8673/3105/1147/5684/5720/5690/5717/9491/10197/7099/4615/23480/7316/10213/5715/5701/9341/5685/5686/5716/7097/5693/5721 70 Bunyavirus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 68/4506 80/10654 2.9031186272219798e-15 2.3125413521985368e-14 1.0913979801586392e-14 3839/23165/5335/348995/57122/11274/23511/4734/23279/23225/1973/3836/4599/9972/8021/7334/55746/7314/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/1977/6233/5610/4940/6396/129401/4928/3838/5903/55706/7175/2316/3841/8638/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/1974/5595/3837/81929/9631/79023/23636/7316/53371/9688/6059/5300/9775/5495/8480 68 Bunyavirus R-HSA-5658442 Regulation of RAS by GAPs 60/4506 68/10654 3.14522011489949e-15 2.4911572955510733e-14 1.1756953180694865e-14 5689/4893/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/3845/3265/4763/5696/5691/7314/5718/5700/122706/5707/23198/5921/9861/5698/5692/5713/5710/5719/6233/200734/5706/84078/5714/64926/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/399473/5693/5721/161742 60 Bunyavirus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 129/4506 182/10654 3.5516997894681726e-15 2.7972144104625043e-14 1.3201381911493358e-14 1912/23165/7068/7486/9112/6045/9212/80012/348995/6613/57122/59348/7181/23511/4929/4792/3190/9759/8856/1911/6790/6672/23279/1387/1789/23225/23512/165918/7067/7428/1107/8924/4152/672/9972/10499/5914/8021/6117/11315/55746/10062/7150/6670/83746/1788/51564/51588/7518/7153/51602/2516/8517/332/10762/5465/1655/5970/2099/79902/9656/9883/84733/3066/7157/668/7158/10155/7155/7690/6396/129401/7703/4791/8554/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/5111/4927/10521/1616/2908/8243/142/1069/8086/7329/367/25942/9641/648/6095/23468/81929/5893/1487/55143/9631/5468/8204/79023/23636/10735/3183/4306/53371/9688/7341/2033/9126/3065/6256/5987/6294/8648/8480/10891/7508/4193 129 Bunyavirus R-HSA-5632684 Hedgehog 'on' state 71/4506 85/10654 4.636096192463237e-15 3.6307405012886244e-14 1.7135186991658918e-14 5689/5682/11127/1452/51684/143471/5705/8452/5709/9978/5695/3549/5711/5683/408/5699/5702/83737/6469/5696/5691/7314/5718/339745/5700/122706/5707/23198/2737/5727/8650/50846/9861/8405/5698/5692/5713/5710/5719/6233/409/79577/5706/5714/2736/5688/5687/5708/25989/5704/7311/5694/57154/5684/5720/2735/5690/5717/9491/10197/64750/132884/7316/10213/5715/5701/5685/5686/5716/5693/5721 71 Bunyavirus R-HSA-437239 Recycling pathway of L1 45/4506 47/10654 5.021374188604884e-15 3.9105003457626864e-14 1.8455506426804193e-14 9252/71/7430/51807/347688/1785/10381/7278/285643/7846/113457/1808/81027/6456/5962/163/6196/1759/6197/161/79861/5594/8650/6714/10376/6195/1213/1211/1175/1173/84617/10382/7277/4478/160/26052/27330/347733/3897/10383/24137/60/84790/7280/112714 45 Bunyavirus R-HSA-2990846 SUMOylation 132/4506 188/10654 5.6473458452195105e-15 4.3735556156866654e-14 2.0640883937205813e-14 1912/23165/7068/7486/9112/6045/9212/80012/348995/6613/57122/59348/7181/23511/4929/4792/3190/9759/8856/1911/6790/6672/23279/1387/1789/23225/10055/23512/165918/7067/7428/1107/8924/4152/672/9972/10499/5914/8021/6117/11315/55746/10062/7150/6670/83746/1788/51564/51588/7518/7153/51602/2516/8517/332/10762/5465/1655/5970/2099/79902/9656/9883/84733/3066/7157/668/7158/10155/7155/7690/6396/129401/7703/4791/8554/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/5111/4927/10521/1616/2908/8243/142/1069/8086/7329/367/25942/9641/648/6095/23468/81929/5893/29843/1487/55143/9631/5468/8204/79023/23636/10735/3183/4306/53371/9688/7341/59343/2033/9126/3065/6256/5987/6294/8648/8480/10891/7508/4193 132 Bunyavirus R-HSA-5696394 DNA Damage Recognition in GG-NER 38/4506 38/10654 5.7455073600325715e-15 4.4249929612626546e-14 2.0883641174878497e-14 10445/9978/10980/10987/7314/83444/86/1643/29844/10920/54891/6233/93973/8607/5886/8451/8450/1642/142/125476/1069/2873/7311/60/8533/10038/51138/7528/9318/7316/64708/283899/4798/79913/54617/5887/50813/7508 38 Bunyavirus R-HSA-9607240 FLT3 Signaling 175/4506 267/10654 7.877303272967196e-15 6.03349492445949e-14 2.8474925075792355e-14 5295/5689/374/4893/6711/71/5682/5526/817/84292/7039/143471/2064/5705/8452/4684/5709/9978/5695/1852/5605/5037/5711/3558/3717/2244/5683/145957/2534/3690/408/5699/5702/4296/5894/9542/2885/6709/8660/8826/9846/5518/4140/3845/3265/4763/5696/5691/7314/5515/54106/5718/818/1839/5290/3667/2065/5700/3815/122706/5707/8844/7094/5594/2069/8074/23198/7414/57761/5921/2260/5528/3718/6714/9861/5519/5698/5692/5713/2335/80824/1445/5710/5719/2906/6233/51332/2266/2243/1843/6777/369/801/200734/5781/30849/28956/805/5170/6464/6712/5747/283455/2322/409/5706/673/4233/84078/5714/64926/6710/5688/5159/5687/5708/3084/5529/816/9693/208/6654/5704/10718/3716/7311/7450/1956/60/5536/2549/5694/7529/5595/5516/5786/815/5684/685/5720/5604/5525/10048/5690/5717/9491/10817/10197/7316/10213/1950/3560/5289/3055/57731/5715/2261/5701/5685/2255/8649/5686/2066/6708/5979/5527/5716/5906/4254/5296/399473/5693/5721/5245/161742 175 Bunyavirus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 62/4506 72/10654 1.3841084495016139e-14 1.0543427205493168e-13 4.975943519922398e-14 8773/55763/5563/71/7531/11127/51807/10971/347688/7533/2810/10381/7278/60412/5898/7846/113457/81027/51552/5879/79861/4644/7534/5872/4641/10376/11336/6844/9882/79058/801/4218/805/84617/7532/10382/7277/23216/5571/347733/208/4012/10383/60/84790/5564/22920/7280/7529/55770/23265/6517/10890/9371/10640/4627/207/112714/8766/149371/9847/54536 62 Bunyavirus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 71/4506 86/10654 1.5605675743223593e-14 1.1822995644594395e-13 5.579832574093105e-14 5295/5335/71/2268/3709/10094/2534/8976/2885/3071/5879/26999/25/1072/5290/10093/10006/4771/5594/4644/4641/6714/10810/7525/7410/5580/7409/23191/3710/10109/10787/2214/5747/2209/1793/6850/10152/5337/10092/4650/10163/4067/55845/998/695/3326/10097/60/5058/63916/5595/3984/4690/4627/10458/3708/3055/10552/10768/4620/8936/917/3320/1398/10096/9844/5296/5581/5338/10095/2212 71 Bunyavirus R-HSA-5688426 Deubiquitination 190/4506 297/10654 1.9835231439049966e-14 1.4946114932992245e-13 7.053780739349207e-14 5689/221937/5682/79594/7419/10474/7321/4738/9817/10445/91833/6478/3091/143471/5705/11274/55031/8239/5709/5695/4792/11047/4609/4194/4089/55432/5711/7347/4088/114803/5683/324/408/5699/8724/8312/5702/8900/8975/672/7187/7040/728386/7345/3054/1540/80351/5696/5691/7314/5718/401447/3607/6314/2648/5700/122706/5707/8737/83444/171023/55611/51720/23198/63967/9101/8517/86/993/890/7417/80124/983/2099/1643/9861/23586/81847/8850/7128/29844/7046/6502/5698/9146/5692/5713/5710/10454/8473/7157/10869/9958/8313/5719/54891/6233/9804/93973/10318/23770/8607/7874/5886/23326/8237/4303/409/330/5706/4287/7706/580/7416/79155/25862/9738/8658/5714/27430/64127/5688/9097/5687/8078/5708/125476/4087/63891/84749/7189/5704/7048/7311/367/114548/387/60/29761/5694/7528/5684/8295/5720/7186/6885/991/51377/10392/5690/2625/57506/5717/9491/4086/1080/57695/10197/64750/29086/7316/10213/8314/55252/8678/9100/7415/5715/283899/3416/5701/4798/329/79913/9099/5685/54617/5686/2033/5728/10868/5716/79184/5887/9736/5693/154/10254/5721/4193 190 Bunyavirus R-HSA-5619084 ABC transporter disorders 65/4506 77/10654 2.4087668322130702e-14 1.7956261840133796e-13 8.474411878036414e-14 5689/5682/143471/91319/5705/5709/5695/5711/5683/5699/6400/5702/51009/5696/5691/7314/5718/5700/122706/5707/10956/79139/91445/23198/9861/5698/215/5692/5713/5710/8647/5719/10613/6233/27248/6048/5706/19/335/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/1244/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 65 Bunyavirus R-HSA-9009391 Extra-nuclear estrogen signaling 65/4506 77/10654 2.4087668322130702e-14 1.7956261840133796e-13 8.474411878036414e-14 5295/2788/374/4893/857/2770/7039/2782/3845/3265/8877/2773/2787/1839/5290/6801/5594/2069/10681/4313/2792/6714/2099/10000/2785/595/2783/2784/2771/7514/2353/801/2791/805/5170/5590/6464/5747/3315/8503/2786/208/1956/858/3480/5595/596/685/54331/2309/59345/207/1027/51764/94235/2100/1950/55970/4314/2793/3320/4846/5296/3276/2790 65 Bunyavirus R-HSA-351202 Metabolism of polyamines 53/4506 59/10654 2.4278378365638115e-14 1.8002159277499752e-13 8.496073056284336e-14 5689/5682/54498/143471/5705/5709/5695/5711/4946/5683/5699/5702/5696/5691/5718/1728/51582/5700/122706/5707/23198/79814/9861/5698/5692/5713/5710/5719/6303/5706/4947/5714/5688/5687/5708/4953/5704/5694/5684/5720/5690/51686/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 53 Bunyavirus R-HSA-9020702 Interleukin-1 signaling 81/4506 103/10654 4.30223788949854e-14 3.17318498304813e-13 1.4975765418750142e-13 8454/5689/4790/5682/8878/143471/5705/5709/9978/5695/4792/5711/5683/5699/5702/3654/7334/3551/5696/5691/7314/5718/8945/1326/11213/5700/122706/5707/23198/23118/8517/5970/9861/5698/5692/5713/5710/10454/5719/6233/4791/351/54472/5706/79155/5714/64127/3552/5688/5687/5708/3656/7189/5704/7311/5694/6416/1147/5684/5720/6885/5604/4215/10392/5690/5717/9491/6500/10197/4615/7316/10213/4793/5715/5701/23291/5685/5686/5716/5693/5721 81 Bunyavirus R-HSA-4086400 PCP/CE pathway 74/4506 92/10654 6.24473809944936e-14 4.581665742438109e-13 2.162305436097424e-13 5689/5579/5682/5578/1212/5582/143471/5705/5709/5695/5711/5683/5699/5702/1855/163/5696/5691/4920/7314/5879/5718/161/5700/122706/5707/1856/23198/9861/5698/5692/5713/23002/5710/5719/6233/1857/1213/1211/1175/1173/144165/409/5706/160/5714/5688/5687/5708/5704/7311/387/5694/57154/5684/5720/5690/5717/9491/50855/10197/64750/7316/10213/5216/5715/5701/5685/5686/23513/5716/5693/5721/6259 74 Bunyavirus R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 38/4506 39/10654 1.321856365499576e-13 9.647475253960255e-13 4.553101286509975e-13 9134/10528/10576/10574/6468/10564/54461/10693/8877/10575/898/10517/26985/26330/26190/10238/7157/83752/26224/2629/8237/63971/6774/26272/26270/55135/22948/84261/10694/8841/22803/7203/908/11328/6950/55294/6499/26234 38 Bunyavirus R-HSA-168325 Viral Messenger RNA Synthesis 41/4506 43/10654 1.3430081270752223e-13 9.750798589285728e-13 4.601864470515427e-13 23165/348995/57122/5431/23511/5435/5433/23279/23225/5439/9972/8021/55746/5438/10762/79902/9883/6396/129401/4928/2963/5434/5903/55706/7175/5436/4927/2962/8086/5432/81929/5440/9631/5430/79023/5441/23636/53371/9688/5437/8480 41 Bunyavirus R-HSA-1227986 Signaling by ERBB2 46/4506 50/10654 1.5584570699315946e-13 1.1256420494739083e-12 5.312438880323135e-13 5295/4893/5335/26469/5578/2064/5753/145957/2534/4145/9542/2885/3845/3265/7314/1839/5290/2065/2069/9101/6714/10000/6233/7525/5580/1729/6464/5782/3084/208/6654/10718/7311/387/1956/2549/11140/8065/685/10273/207/7316/1950/3320/2066/5581 46 Bunyavirus R-HSA-191859 snRNP Assembly 48/4506 53/10654 2.0164775354717048e-13 1.4415229151013111e-12 6.803230551523971e-13 23165/6633/6606/8487/25929/348995/57122/23511/23279/23225/79084/9972/8021/55746/10762/79902/9883/6636/10419/6396/129401/50628/4928/6635/5903/6632/55706/7175/6637/54960/4927/51808/8086/79833/22916/81929/11218/9631/79023/23636/4686/53371/9688/1207/6634/8480/6628/79760 48 Bunyavirus R-HSA-194441 Metabolism of non-coding RNA 48/4506 53/10654 2.0164775354717048e-13 1.4415229151013111e-12 6.803230551523971e-13 23165/6633/6606/8487/25929/348995/57122/23511/23279/23225/79084/9972/8021/55746/10762/79902/9883/6636/10419/6396/129401/50628/4928/6635/5903/6632/55706/7175/6637/54960/4927/51808/8086/79833/22916/81929/11218/9631/79023/23636/4686/53371/9688/1207/6634/8480/6628/79760 48 Bunyavirus R-HSA-5358351 Signaling by Hedgehog 107/4506 149/10654 2.031695781139818e-13 1.444991795361687e-12 6.819601843245899e-13 8454/5689/5682/11127/1452/51684/143471/10381/5705/7278/8452/5709/9978/5695/3549/5711/7846/113457/5683/408/5699/6400/5702/81027/83737/51009/6469/5696/5691/7314/5718/8945/79659/339745/5700/122706/5707/5567/10956/27152/23198/2737/5727/8650/50846/9861/8405/2932/5698/5692/5713/10376/5710/5719/6233/27248/23322/84617/54903/10382/409/79577/8100/7277/5706/84447/5714/5566/2736/5688/5687/347733/5708/25989/5577/5704/7311/147111/10383/84790/5694/7280/57154/5684/5720/2735/5690/5717/9491/6500/10197/64750/132884/7316/10213/2778/7415/5715/5701/5576/5685/5686/5716/8481/5693/5721/5034 107 Bunyavirus R-HSA-5610787 Hedgehog 'off' state 86/4506 113/10654 2.1290273396780557e-13 1.5065300058432536e-12 7.110029854655544e-13 8454/5689/5682/11127/1452/51684/143471/10381/5705/7278/5709/9978/5695/5711/7846/113457/5683/5699/5702/81027/83737/5696/5691/7314/5718/8945/79659/5700/122706/5707/5567/27152/23198/2737/5727/8650/9861/2932/5698/5692/5713/10376/5710/5719/6233/23322/84617/54903/10382/8100/7277/5706/5714/5566/2736/5688/5687/347733/5708/5577/5704/7311/10383/84790/5694/7280/5684/5720/2735/5690/5717/9491/6500/10197/7316/10213/2778/5715/5701/5576/5685/5686/5716/8481/5693/5721 86 Bunyavirus R-HSA-9013694 Signaling by NOTCH4 67/4506 82/10654 2.322832763083895e-13 1.6353681170398738e-12 7.718078027259089e-13 8454/5689/5682/23385/5705/5709/9978/5695/22938/5711/1387/4088/5683/5699/5702/5696/5691/7314/5718/2648/5700/5707/3280/7534/102/9861/8850/5698/5692/5713/5710/5719/6233/2324/5663/5706/5714/5688/5687/5708/59/4855/5704/7311/5694/4851/5684/5720/23462/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/2033/55294/5716/3516/5693/5721 67 Bunyavirus R-HSA-5684996 MAPK1/MAPK3 signaling 165/4506 255/10654 2.5215622591101313e-13 1.7663606980902126e-12 8.33629416526756e-13 5689/374/4893/6711/71/5682/5526/817/84292/7039/143471/2064/5705/8452/4684/5709/9978/5695/1852/5605/5037/5711/3558/3717/2244/5683/145957/2534/3690/408/5699/5702/4296/5894/9542/2885/6709/8660/8826/5518/4140/3845/3265/4763/3569/5696/5691/7314/5515/5718/818/1839/3667/2065/5700/3815/122706/5707/8844/7094/5594/2069/8074/23198/7414/5921/2260/5528/983/3718/6714/9861/5519/5698/5692/5713/2335/80824/1445/5710/5719/2906/6233/51332/2266/2243/1843/369/801/200734/7297/5781/28956/805/6464/6712/5747/283455/2322/409/5706/673/4233/84078/5714/64926/6710/5688/5159/5687/5708/3084/5529/816/9693/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/7529/5595/5516/5786/815/5684/685/5720/5604/5525/10048/5690/5717/9491/10817/10197/7316/10213/1950/3560/57731/5715/2261/5701/5685/2255/8649/5686/2066/6708/5979/5527/5716/5906/4254/399473/5693/5721/5245/161742 165 Bunyavirus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 40/4506 42/10654 3.0453817609130714e-13 2.1226310873564107e-12 1.0017703160898262e-12 23165/348995/57122/23511/81608/23279/23225/9972/8021/55746/53981/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/7884/4927/10898/10482/51692/8086/22916/81929/9631/29894/79023/23636/4686/8189/53371/9688/10189/8480/55339 40 Bunyavirus R-HSA-5689603 UCH proteinases 79/4506 102/10654 3.9490441477378343e-13 2.7387898218639505e-12 1.2925648558974321e-12 5689/221937/5682/4738/10445/143471/5705/5709/5695/11047/5711/7347/5683/5699/5702/7040/7345/3054/5696/5691/7314/5718/3607/5700/122706/5707/83444/171023/23198/86/9861/29844/7046/5698/5692/5713/5710/8473/9958/5719/54891/6233/93973/8607/5706/580/5714/5688/5687/5708/125476/5704/7048/7311/60/5694/7528/5684/5720/51377/5690/5717/9491/10197/7316/10213/8314/55252/5715/283899/5701/4798/79913/5685/54617/5686/5716/5693/5721 79 Bunyavirus R-HSA-68962 Activation of the pre-replicative complex 33/4506 33/10654 4.342334042537109e-13 2.9966404234142228e-12 1.4142567882155775e-12 5422/4174/84515/4998/10926/990/55388/6117/5001/5558/6118/23594/5557/4175/23649/4999/4172/5000/8318/54107/4173/51053/6119/5427/81620/29935/23595/4176/56655/1017/8317/5426/4171 33 Bunyavirus R-HSA-5673001 RAF/MAP kinase cascade 161/4506 249/10654 5.407839570044862e-13 3.713560768789427e-12 1.7526055127187137e-12 5689/374/4893/6711/71/5682/5526/817/84292/7039/143471/2064/5705/8452/4684/5709/9978/5695/1852/5605/5037/5711/3558/3717/2244/5683/145957/2534/3690/408/5699/5702/4296/5894/9542/2885/6709/8660/8826/5518/4140/3845/3265/4763/5696/5691/7314/5515/5718/818/1839/3667/2065/5700/3815/122706/5707/8844/7094/5594/2069/8074/23198/7414/5921/2260/5528/3718/6714/9861/5519/5698/5692/5713/2335/80824/1445/5710/5719/2906/6233/51332/2266/2243/1843/369/801/200734/28956/805/6464/6712/5747/283455/2322/409/5706/673/4233/84078/5714/64926/6710/5688/5159/5687/5708/3084/5529/816/9693/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/7529/5595/5516/5786/815/5684/685/5720/5604/5525/10048/5690/5717/9491/10817/10197/7316/10213/1950/3560/57731/5715/2261/5701/5685/2255/8649/5686/2066/6708/5979/5527/5716/5906/4254/399473/5693/5721/5245/161742 161 Bunyavirus R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 53/4506 61/10654 5.489339513569231e-13 3.7510486676056406e-12 1.7702978307434312e-12 71/10094/8976/2885/3071/5879/26999/25/1072/10093/10006/4771/5594/4644/4641/10810/7410/7409/23191/10109/10787/2214/5747/2209/1793/6850/10152/10092/4650/10163/55845/998/695/3326/10097/60/5058/63916/5595/3984/4690/4627/10458/10552/4620/8936/917/3320/1398/10096/9844/10095/2212 53 Bunyavirus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 39/4506 41/10654 6.897032277886644e-13 4.689981948962918e-12 2.2134249929032873e-12 23165/348995/57122/23511/81608/23279/23225/9972/8021/55746/53981/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10898/10482/51692/8086/22916/81929/9631/29894/79023/23636/4686/8189/53371/9688/10189/8480/55339 39 Bunyavirus R-HSA-176187 Activation of ATR in response to replication stress 36/4506 37/10654 7.082705957987182e-13 4.792860245356375e-12 2.2619781419223246e-12 5982/4174/84515/4998/10926/990/84126/55388/6117/5001/6118/23594/63967/993/5985/4175/5984/5884/5810/4999/4172/5000/8318/4173/6119/3364/1111/23595/5983/4176/1017/5883/8317/545/4171/995 36 Bunyavirus R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 46/4506 51/10654 9.36134544161395e-13 6.304210408507172e-12 2.975255988308528e-12 51807/347688/10381/7278/1780/5048/8655/84516/832/636/7846/113457/81027/51164/79861/23299/5870/10376/10540/140735/84617/11258/1783/10382/93661/55860/830/7277/10671/1639/347733/51143/10383/84790/5049/7280/829/1778/5321/5050/112714/1781/22930/25782/10121/51560 46 Bunyavirus R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 32/4506 32/10654 1.030940371028811e-12 6.909283063529627e-12 3.2608184812399135e-12 51807/10381/7278/10576/7846/113457/7411/81027/10574/10693/5201/79861/5204/10575/10471/10376/5202/84617/10382/7277/347733/10383/60/84790/22948/7280/10694/5203/112714/7203/908/6950 32 Bunyavirus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 78/4506 102/10654 1.8246335989092195e-12 1.2170044195595465e-11 5.743621250658587e-12 8454/8792/7124/5689/5682/356/9039/143471/5705/10673/5709/5695/7133/5711/5683/5699/5702/8740/944/7187/51330/958/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/9861/5698/5692/5713/5710/9040/5719/6233/8742/4791/959/4055/8600/330/5706/5714/5688/5687/5708/5704/7311/5971/115650/5694/1147/4050/5684/5720/7186/5690/5717/9491/6500/10197/7316/10213/5715/5701/329/23291/5685/5686/4049/5716/5693/5721 78 Bunyavirus R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 45/4506 50/10654 2.010627780369536e-12 1.3346738694453016e-11 6.298959211684011e-12 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/2209/5706/5714/5688/5687/5708/5704/5694/5684/5720/5690/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 45 Bunyavirus R-HSA-1236975 Antigen processing-Cross presentation 76/4506 99/10654 2.4859026182639723e-12 1.6423451421137333e-11 7.75100591875771e-12 8773/5689/5682/55176/811/143471/5705/5709/5695/3106/5711/5683/5699/5702/3551/5696/5691/7314/5718/10952/5700/122706/5707/23198/6892/8517/9861/5698/5692/5713/5710/5719/6233/3685/1535/3135/653361/6890/2209/5706/9554/29927/5714/5688/5687/5708/2923/695/5704/4012/7311/5694/8673/3105/1147/5684/5720/5690/5717/9491/10197/7099/4615/23480/7316/10213/5715/5701/9341/5685/5686/5716/7097/1536/5693/5721 76 Bunyavirus R-HSA-5633007 Regulation of TP53 Activity 111/4506 160/10654 2.9259821285234195e-12 1.9239712675290786e-11 9.080133219101972e-12 5563/64769/9156/1459/7486/6874/9212/5982/1460/11200/472/639/84289/1457/6790/29117/4194/5928/1432/4683/56950/84126/1107/8900/2475/672/5518/6117/11198/7159/51230/7314/5515/23774/6118/6446/117584/890/983/5519/10000/5985/7994/3066/7157/5984/6233/10419/7874/5884/5810/26155/26013/253260/5170/1029/9219/8445/204851/6878/5931/580/11073/80196/641/1108/8148/64223/6119/3364/5571/10524/1616/6794/54815/1111/8626/208/7311/7161/5562/6880/6908/5983/5564/1020/53615/5516/1017/9891/5883/10111/207/22974/6749/545/7316/6872/6879/112858/9099/2033/3065/91875/5527/5932/8851/5300/133746/10919/4193 111 Bunyavirus R-HSA-8856828 Clathrin-mediated endocytosis 103/4506 146/10654 3.4911156982167223e-12 2.284795907659207e-11 1.0783035885275274e-11 374/85439/71/8674/5286/4738/7039/1212/1785/29763/950/10094/554/55738/10980/2017/3482/408/10987/6456/8976/30011/2885/163/1759/3312/7314/23396/1839/161/7018/5868/10618/10093/1856/9892/2060/2069/1601/6453/55707/8301/9146/4074/10920/29979/6233/6844/1213/2580/1211/29924/1175/10109/1173/6857/84251/23048/9026/409/382/160/338/920/22905/26052/10092/9829/2873/10097/7311/1956/60/8533/51429/8673/3092/50618/51138/9318/685/1080/29978/58513/7316/1950/273/64708/10552/26130/3949/867/9341/915/917/115548/5878/10096/143425/3575/154/10254/50813 103 Bunyavirus R-HSA-4608870 Asymmetric localization of PCP proteins 54/4506 64/10654 4.097980589314928e-12 2.6694322156565468e-11 1.2598317109305609e-11 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/1856/23198/9861/5698/5692/5713/5710/5719/6233/144165/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/50855/10197/64750/7316/10213/5715/5701/5685/5686/23513/5716/5693/5721 54 Bunyavirus R-HSA-6811440 Retrograde transport at the Trans-Golgi-Network 44/4506 49/10654 4.30881999217503e-12 2.7937186367869733e-11 1.3184883696986017e-11 400/60592/8674/3482/9382/10228/6293/8675/2800/339122/7110/10618/55275/51209/10466/9827/22836/5870/79571/91949/4074/2803/8677/10139/51542/22796/8775/10244/9648/90196/57589/25839/83548/63908/738/9367/10226/9341/57511/51560/8774/143187/4905/84342 44 Bunyavirus R-HSA-168253 Host Interactions with Influenza Factors 39/4506 42/10654 5.696848899854326e-12 3.676577484443023e-11 1.7351513462031943e-11 3839/23165/348995/57122/23511/23279/23225/3836/9972/8021/7040/55746/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/3841/293/4927/10898/3840/8086/3837/81929/9631/79023/23636/53371/9688/8480 39 Bunyavirus R-HSA-8848021 Signaling by PTK6 47/4506 54/10654 1.0278293971763805e-11 6.572450365430616e-11 3.1018511503391496e-11 4893/5770/27043/3091/2064/5753/145957/9542/9564/3845/3265/5829/7314/5879/120892/1839/2065/2069/898/202559/5921/6421/595/6233/1019/10657/1793/6774/2908/3084/10718/7311/2034/387/1956/63916/1017/685/207/1027/7316/1950/867/2066/1398/9844/10656 47 Bunyavirus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 47/4506 54/10654 1.0278293971763805e-11 6.572450365430616e-11 3.1018511503391496e-11 4893/5770/27043/3091/2064/5753/145957/9542/9564/3845/3265/5829/7314/5879/120892/1839/2065/2069/898/202559/5921/6421/595/6233/1019/10657/1793/6774/2908/3084/10718/7311/2034/387/1956/63916/1017/685/207/1027/7316/1950/867/2066/1398/9844/10656 47 Bunyavirus R-HSA-71291 Metabolism of amino acids and derivatives 221/4506 372/10654 1.0568885237996656e-11 6.727409142359515e-11 3.174983549025672e-11 6158/6470/5689/6138/38/11019/6227/6206/6234/6191/1373/4548/6128/5682/6132/6129/5160/2806/2639/9255/6176/383/594/54498/6224/6146/6154/143471/6202/5705/6169/1491/5709/6175/6218/5695/6173/6167/5711/4946/116832/5683/5831/6156/5699/6143/5702/6139/10295/3921/29968/1734/387787/6208/5696/6170/5691/7296/593/5718/6203/1728/29920/23743/6147/51582/5700/122706/5707/4143/191/6222/549/57494/2936/1468/8528/23198/1737/27232/6134/60678/6155/9380/79814/84706/6231/9861/6142/2747/9061/2752/23521/5832/5698/8604/5692/5713/5162/5710/26227/6207/5719/6233/7306/501/6188/189/6303/2744/435/200916/6122/4942/6230/4967/6194/6166/3028/2954/25828/1743/6136/635/2805/6125/5706/4947/6232/6160/5714/6193/8140/6210/6229/6205/102724560/5688/23464/5687/5708/140801/6235/6181/4953/54363/3034/5704/7311/6223/25873/10157/36/5694/121278/9045/6187/10993/9060/26275/6168/2746/6157/6137/440/6144/5684/9349/4736/5720/51121/6159/9521/6217/8659/56922/6152/5690/51686/5717/9491/51065/6141/6123/113675/259307/10197/6164/10213/586/79048/10165/7263/6209/11224/6165/11112/6130/5715/6204/5701/6228/51540/1152/5685/7965/5686/445/6124/6520/5716/4706/1738/4507/6189/6135/6201/6161/5693/5721/6133 221 Bunyavirus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 66/4506 84/10654 1.073294050171841e-11 6.800781390634302e-11 3.2096113940545486e-11 10445/5982/6613/9978/85015/10980/10987/6117/7334/7314/6118/83444/86/3978/1643/29844/5985/10920/5984/54891/6233/93973/8607/5424/5886/8451/8554/7515/54107/8450/4331/5425/5111/6119/5427/1642/142/125476/1069/7329/2873/7311/3980/60/8533/5983/10038/51138/7528/56655/9318/7336/54778/7316/64708/5426/283899/7341/4798/79913/54617/5887/5981/1022/50813/7508 66 Bunyavirus R-HSA-5694530 Cargo concentration in the ER 32/4506 33/10654 2.0125563307832063e-11 1.2694586086478685e-10 5.991177455296518e-11 6811/374/10960/2153/10484/7039/9570/90411/3998/375056/9632/1294/81562/254263/51128/10175/10959/2348/2890/10802/2157/9554/966/149111/79748/9871/1075/10113/1522/5265/10972/10427 32 Bunyavirus R-HSA-168276 NS1 Mediated Effects on Host Pathways 37/4506 40/10654 2.7740817569883488e-11 1.7419234095683595e-10 8.220963006722229e-11 3839/23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/3841/4927/10898/3840/8086/3837/81929/9631/79023/23636/53371/9688/8480 37 Bunyavirus R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 28/4506 28/10654 3.271246261656121e-11 2.044895645178759e-10 9.650832728511097e-11 10381/7278/10576/7846/113457/7411/81027/10574/10693/5201/5204/10575/10471/5202/84617/10382/7277/347733/10383/60/84790/22948/7280/10694/5203/7203/908/6950 28 Bunyavirus R-HSA-176033 Interactions of Vpr with host cellular proteins 34/4506 36/10654 4.0246257396170795e-11 2.504610839743843e-10 1.1820446838630993e-10 23165/348995/57122/23511/292/23279/23225/3836/9972/8021/55746/10762/79902/11168/9883/6396/129401/4928/5903/55706/7175/293/4927/8086/81929/9631/3159/79023/23636/53371/9688/8815/8480/291 34 Bunyavirus R-HSA-5626467 RHO GTPases activate IQGAPs 31/4506 32/10654 4.6354534747503106e-11 2.8719209528008593e-10 1.3553957528509682e-10 71/6249/51807/347688/10381/7278/7846/113457/81027/8826/5879/79861/999/10376/128239/801/4221/805/84617/10382/7277/347733/998/10788/10383/60/84790/7280/1495/1499/112714 31 Bunyavirus R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 38/4506 42/10654 7.800516506499655e-11 4.81146903100023e-10 2.2707605107416326e-10 2788/6000/1459/2770/1460/2775/10576/1457/2782/10574/10693/2773/2787/10575/10681/8786/2792/2785/2783/2784/2771/2791/5082/2786/22948/9628/10694/54331/59345/8787/51764/94235/7203/908/55970/2793/6950/2790 38 Bunyavirus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 33/4506 35/10654 9.034839744162681e-11 5.548267226151003e-10 2.618490535637226e-10 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/7884/4927/10482/8086/22916/81929/9631/79023/23636/4686/53371/9688/10189/8480 33 Bunyavirus R-HSA-6803529 FGFR2 alternative splicing 26/4506 26/10654 1.8412653872456316e-10 1.1257561183422853e-9 5.312977225431763e-10 54845/5431/5435/5433/5439/7072/7073/5438/3185/4670/5725/2963/5434/5436/2962/80004/5432/22916/5440/23543/5430/3178/5441/4686/5437/3187 26 Bunyavirus R-HSA-4570464 SUMOylation of RNA binding proteins 41/4506 47/10654 1.9321004487097553e-10 1.176134508952576e-9 5.550736752211433e-10 1912/23165/6045/80012/348995/6613/57122/23511/3190/1911/23279/23225/9972/8021/55746/51602/10762/79902/9883/84733/6396/129401/7703/4928/5903/55706/7175/8535/4927/8086/7329/648/81929/9631/79023/23636/3183/53371/9688/7341/8480 41 Bunyavirus R-HSA-159227 Transport of the SLBP independent Mature mRNA 32/4506 34/10654 2.0247013337437473e-10 1.2218327529172224e-9 5.766408446524685e-10 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10482/8086/22916/81929/9631/79023/23636/4686/53371/9688/10189/8480 32 Bunyavirus R-HSA-4085377 SUMOylation of SUMOylation proteins 32/4506 34/10654 2.0247013337437473e-10 1.2218327529172224e-9 5.766408446524685e-10 23165/348995/6613/57122/23511/23279/23225/9972/8021/55746/51588/10762/79902/9883/6396/129401/4928/5903/55706/7175/10210/4927/8086/7329/81929/9631/79023/23636/53371/9688/7341/8480 32 Bunyavirus R-HSA-446652 Interleukin-1 family signaling 96/4506 140/10654 2.412968928579927e-10 1.4498615027760424e-9 6.842584302914947e-10 8454/5689/4790/5682/1511/26469/8878/143471/5705/5709/9978/5695/4792/5711/4088/5683/5699/5702/3654/7334/3551/5696/5691/7314/5718/8945/1326/11213/5700/122706/5707/29110/23198/23118/8517/5970/9861/5698/5692/5713/5710/10454/5719/6233/5781/4791/56300/351/5782/54472/5706/79155/6774/5780/5714/64127/3552/5688/5687/5708/3656/5771/7189/5704/7311/5694/6416/1147/5684/5720/6885/5604/4215/10392/5690/5717/9491/6500/25930/10197/4615/7316/10213/27179/4793/5775/5715/5701/23291/5685/5686/5716/5599/5784/5693/5721 96 Bunyavirus R-HSA-6806003 Regulation of TP53 Expression and Degradation 34/4506 37/10654 2.935220597205154e-10 1.7560933530060018e-9 8.287837692582884e-10 11200/472/639/4194/8900/2475/5518/51230/7314/5515/6446/117584/890/983/5519/10000/7157/6233/7874/253260/5170/1029/80196/64223/1616/208/7311/5516/1017/207/7316/9099/5527/4193 34 Bunyavirus R-HSA-72165 mRNA Splicing - Minor Pathway 44/4506 52/10654 3.4833754007333986e-10 2.0751390207787853e-9 9.793565566614372e-10 6633/6431/4904/51639/23450/5431/5435/5433/9416/23020/5439/9410/10907/10262/6432/83443/5438/9343/6636/2963/6635/5434/6632/24148/5436/6637/57819/2962/6426/5432/22916/23451/5440/5430/85437/11325/5441/10594/4686/5437/6634/6427/10992/6628 44 Bunyavirus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 25/4506 25/10654 4.3675094400878915e-10 2.579791593001068e-9 1.2175260481957772e-9 11065/7321/8697/51529/29945/51434/9184/29882/7314/996/51433/119504/7324/64682/6233/246184/8881/10393/7311/25906/991/7316/4085/4751/701 25 Bunyavirus R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 25/4506 25/10654 4.3675094400878915e-10 2.579791593001068e-9 1.2175260481957772e-9 51807/10381/7278/10576/7846/113457/81027/10574/10693/79861/10575/10376/84617/10382/7277/347733/10383/84790/22948/7280/10694/112714/7203/908/6950 25 Bunyavirus R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 31/4506 33/10654 4.5290359206241027e-10 2.6527210392226884e-9 1.2519449139274944e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/3303/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/3304/81929/9631/79023/23636/53371/9688/8480 31 Bunyavirus R-HSA-180910 Vpr-mediated nuclear import of PICs 31/4506 33/10654 4.5290359206241027e-10 2.6527210392226884e-9 1.2519449139274944e-9 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/11168/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/3159/79023/23636/53371/9688/8815/8480 31 Bunyavirus R-HSA-6804757 Regulation of TP53 Degradation 33/4506 36/10654 6.414719379416391e-10 3.741472307492238e-9 1.7657782920657321e-9 11200/472/4194/8900/2475/5518/51230/7314/5515/6446/117584/890/983/5519/10000/7157/6233/7874/253260/5170/1029/80196/64223/1616/208/7311/5516/1017/207/7316/9099/5527/4193 33 Bunyavirus R-HSA-6790901 rRNA modification in the nucleus and cytosol 50/4506 62/10654 6.557314251998722e-10 3.808706694702591e-9 1.7975093892540358e-9 55226/10528/84135/27340/88745/51096/55272/51077/23160/10607/11103/6208/22984/10813/9136/6203/27292/56902/51602/9724/54555/10171/5822/2091/55651/55127/8602/6194/10436/9277/84128/4839/134430/92856/65083/11056/9790/51202/57647/6187/79050/55813/25879/57050/1736/10199/25926/27341/6201/10885 50 Bunyavirus R-HSA-73894 DNA Repair 196/4506 334/10654 6.888329386814869e-10 3.9843697780995544e-9 1.88041313245656e-9 2237/4436/221120/151987/4350/5892/9156/2074/7486/56852/10445/5982/8505/11200/472/6613/80198/3981/5431/5435/2140/9978/5433/85015/26277/10980/4683/25898/165918/84126/54890/5439/10987/8900/8924/672/6117/7334/10973/55666/54386/348654/55183/7314/51514/22909/7014/6118/2176/25/5888/322/328/83444/51588/7518/51720/63967/5531/9636/86/5438/3978/890/1643/7517/9656/84464/51455/29844/2177/5985/10920/29089/7157/5984/4255/54891/6233/7158/6047/93973/8607/7874/5884/5810/5424/5886/57697/8451/8554/10450/8467/124739/3838/5434/5436/2956/7515/54107/7013/4292/7706/580/11073/5591/8450/4331/5425/641/5111/6119/83932/3364/22976/10524/5427/1161/55775/1642/5429/142/125476/1111/55215/1069/7329/9246/2873/7311/23030/3980/60/5536/8533/5983/2175/10038/2547/5432/51138/7528/56655/9318/51750/1017/54962/25913/6917/5440/5893/84164/5883/27339/5430/10111/7320/7520/675/51548/545/5441/7336/29086/54778/7316/64708/8314/5426/9100/10635/10459/7415/5395/283899/7341/4798/5437/79913/54617/65057/2033/8914/7398/5932/9025/79184/56949/5887/9716/5599/5981/1022/8178/50813/7508 196 Bunyavirus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 59/4506 77/10654 8.191925741343484e-10 4.703188124255145e-9 2.219657613576581e-9 1912/23165/7486/6045/80012/348995/6613/57122/23511/1911/6672/23279/23225/165918/8924/672/9972/8021/6117/55746/51564/51588/7518/10762/79902/9656/9883/84733/6396/129401/7703/8554/4928/5903/55706/7175/1029/8535/5885/641/4927/8243/142/1069/8086/7329/648/81929/5893/9631/79023/23636/10735/53371/9688/7341/9126/8480/7508 59 Bunyavirus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 69/4506 94/10654 8.198527361506458e-10 4.703188124255145e-9 2.219657613576581e-9 8454/3725/9252/4790/7321/4792/1432/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/11035/8945/1326/5606/8737/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/6195/10454/3661/6233/10010/2353/8772/4791/3665/351/330/7098/79155/64127/5602/3656/7189/7311/9641/6416/5595/5516/1147/1845/6885/5604/10392/6500/7316/4793/7322/329/23291/5609/5599 69 Bunyavirus R-HSA-4615885 SUMOylation of DNA replication proteins 39/4506 45/10654 8.314116250726017e-10 4.749950021931175e-9 2.241726771658223e-9 23165/9212/348995/6613/57122/23511/6790/23279/23225/9972/8021/55746/7150/51588/7153/332/10762/79902/9883/7155/6396/129401/4928/5903/55706/7175/5111/4927/8086/7329/81929/55143/9631/79023/23636/53371/9688/7341/8480 39 Bunyavirus R-HSA-5673000 RAF activation 30/4506 32/10654 1.0111365023075884e-9 5.753160343741952e-9 2.7151893187636643e-9 4893/5526/817/5605/3717/4296/5894/5518/4140/3845/3265/5515/818/8844/5528/6714/5519/369/801/805/673/5529/816/7529/5516/815/5604/5525/5527/5245 30 Bunyavirus R-HSA-3371571 HSF1-dependent transactivation 24/4506 24/10654 1.0358461701948771e-9 5.8697949644376375e-9 2.7702347298750457e-9 817/3305/1387/2475/3306/3312/818/3303/84335/3337/3297/57521/1410/64223/26353/3281/816/3326/3304/10728/815/3320/2033/2288 24 Bunyavirus R-HSA-373760 L1CAM interactions 83/4506 119/10654 1.084578977150424e-9 6.1210651584926765e-9 2.888821055695781e-9 9252/6711/71/7430/1459/51807/286/347688/1785/1460/10381/7278/8829/4684/3688/1457/285643/5605/7846/113457/3690/1808/81027/6456/6709/5962/163/6196/1759/6197/3312/5879/6326/161/79861/5594/284217/2260/8650/1272/6714/10376/6195/7410/51332/3685/1213/1211/1175/1173/84617/6712/10382/7277/4478/160/3912/26052/6710/27330/347733/6386/1641/3897/10383/24137/1956/60/84790/5058/8506/7280/5595/5604/10048/11313/112714/3915/57731/3673/6708/287/288 83 Bunyavirus R-HSA-75067 Processing of Capped Intronless Pre-mRNA 27/4506 28/10654 1.2899694763842155e-9 7.250876814837083e-9 3.42203277903283e-9 51585/81608/1477/53981/11051/8106/1478/23283/6636/10914/6635/7884/84967/6637/10898/51692/22916/1479/25888/79869/29894/4686/8189/10978/6634/55339/6628 27 Bunyavirus R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 32/4506 35/10654 1.3984353166570116e-9 7.828991290842868e-9 3.694872428284221e-9 23165/91754/348995/57122/23511/23279/23225/9972/8021/55746/10762/983/79902/9883/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/81929/9631/10783/79023/23636/53371/9688/8480 32 Bunyavirus R-HSA-6802957 Oncogenic MAPK signaling 55/4506 71/10654 1.507473800004028e-9 8.40567390882246e-9 3.967036315800074e-9 4893/71/817/54845/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/4763/818/8805/8844/7094/5594/7414/23164/57085/6714/9061/2335/1445/2266/2243/369/801/57670/805/283455/409/673/816/56829/7450/60/9444/7529/5595/4000/27044/815/22906/8087/5604/10018/10142/5906/5245 55 Bunyavirus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 40/4506 47/10654 1.5912752970886947e-9 8.733219543864726e-9 4.121620641029566e-9 4893/71/817/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/409/673/816/7450/60/7529/5595/815/5604/5906/5245 40 Bunyavirus R-HSA-6802949 Signaling by RAS mutants 40/4506 47/10654 1.5912752970886947e-9 8.733219543864726e-9 4.121620641029566e-9 4893/71/817/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/409/673/816/7450/60/7529/5595/815/5604/5906/5245 40 Bunyavirus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 40/4506 47/10654 1.5912752970886947e-9 8.733219543864726e-9 4.121620641029566e-9 4893/71/817/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/409/673/816/7450/60/7529/5595/815/5604/5906/5245 40 Bunyavirus R-HSA-9649948 Signaling downstream of RAS mutants 40/4506 47/10654 1.5912752970886947e-9 8.733219543864726e-9 4.121620641029566e-9 4893/71/817/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/409/673/816/7450/60/7529/5595/815/5604/5906/5245 40 Bunyavirus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 34/4506 38/10654 1.64950898624106e-9 9.017315791451128e-9 4.255699138908824e-9 23165/348995/57122/23511/23279/23225/7428/9972/8021/55746/51588/10762/79902/9883/6396/129401/8554/4928/5903/55706/7175/4927/8086/7329/81929/9631/79023/23636/53371/9688/7341/5987/8480/4193 34 Bunyavirus R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 29/4506 31/10654 2.252805722619246e-9 1.221949874447949e-8 5.766961198595244e-9 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/3837/81929/9631/79023/23636/53371/9688/8480 29 Bunyavirus R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 29/4506 31/10654 2.252805722619246e-9 1.221949874447949e-8 5.766961198595244e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/81929/9631/79023/23636/53371/9688/8480 29 Bunyavirus R-HSA-2980766 Nuclear Envelope Breakdown 43/4506 52/10654 2.3947476637364246e-9 1.2939062958327813e-8 6.106557690066363e-9 23165/5579/91754/5578/348995/57122/23511/23279/23225/4001/9972/8021/55746/10762/983/79902/9883/7444/2010/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/5347/7112/4000/81929/9631/10783/79023/23636/7443/53371/9688/8815/23399/8480 43 Bunyavirus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 23/4506 23/10654 2.4564087966410237e-9 1.3220980164160569e-8 6.239607794759764e-9 11065/7321/8697/51529/29945/51434/29882/7314/996/983/51433/119504/7324/64682/6233/246184/8881/891/10393/7311/25906/991/7316 23 Bunyavirus R-HSA-5689880 Ub-specific processing proteases 136/4506 220/10654 3.0709144076939264e-9 1.646482570894359e-8 7.770532408132405e-9 5689/5682/79594/7419/10474/9817/91833/6478/3091/143471/5705/11274/55031/8239/5709/5695/4792/11047/4609/4194/4089/5711/4088/5683/408/5699/8724/8312/5702/8900/8975/728386/1540/80351/5696/5691/7314/5718/401447/6314/2648/5700/122706/5707/8737/55611/23198/63967/9101/8517/993/890/7417/1643/9861/23586/81847/7046/6502/5698/9146/5692/5713/5710/10454/7157/10869/9958/8313/5719/6233/9804/23770/8607/7874/23326/8237/4303/409/330/5706/7416/25862/9738/8658/5714/27430/5688/9097/5687/8078/5708/4087/63891/84749/7189/5704/7311/367/29761/5694/5684/8295/5720/7186/6885/991/5690/2625/5717/9491/4086/1080/57695/10197/64750/7316/10213/8678/9100/5715/3416/5701/329/9099/5685/5686/5728/10868/5716/9736/5693/154/10254/5721/4193 136 Bunyavirus R-HSA-913531 Interferon Signaling 125/4506 199/10654 3.2644250870551604e-9 1.74352818825858e-8 8.2285367187315e-9 3839/23165/5335/960/5770/817/348995/3383/57122/11274/3115/23511/4684/4734/6672/3113/23279/3106/3459/3717/23225/3117/1973/3836/4599/9972/117854/8021/3127/7334/55746/5696/7314/818/7412/10410/9830/9636/3126/2634/10762/2317/103/3434/3433/79902/23586/9883/1981/10612/3458/3661/7324/1977/6233/5580/10107/5610/4940/6396/3437/129401/6773/7297/5781/3660/8554/3135/3665/3120/4928/3838/5903/55706/7175/2316/3841/3123/23650/2209/8638/25820/1982/7706/9470/3122/6772/4927/3659/3840/5771/3454/816/8086/9246/3716/7311/3125/3105/1974/5595/3460/815/3837/81929/6737/51447/9631/23321/4281/3119/79023/23636/51127/7316/53371/9688/7341/6059/55128/5300/9775/5495/5724/8480 125 Bunyavirus R-HSA-6802952 Signaling by BRAF and RAF fusions 52/4506 67/10654 3.765369751094783e-9 2.0034066538267664e-8 9.455026494311932e-9 4893/71/817/54845/5605/5037/3717/2244/3690/408/5894/8826/4140/3845/3265/818/8805/8844/7094/5594/7414/23164/57085/6714/9061/2335/1445/2266/2243/369/801/57670/805/283455/409/673/816/56829/7450/60/9444/7529/5595/4000/27044/815/22906/8087/5604/10018/10142/5906 52 Bunyavirus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 59/4506 79/10654 4.599350899683504e-9 2.4378308570946026e-8 1.1505280417459238e-8 2074/5982/5431/5435/9978/5433/10980/5439/10987/6117/7314/6118/5438/3978/5985/10920/5984/6233/7874/5424/8451/10450/5434/5436/7515/54107/8450/4331/5425/5111/6119/5427/1161/1642/2873/7311/3980/8533/5983/5432/51138/56655/9318/6917/5440/27339/5430/5441/7316/64708/5426/5437/2033/56949/9716/5981/1022/8178/50813 59 Bunyavirus R-HSA-1250196 SHC1 events in ERBB2 signaling 22/4506 22/10654 5.824384104792016e-9 3.0638458272000265e-8 1.445974206750749e-8 4893/5578/2064/145957/9542/2885/3845/3265/1839/2065/2069/5580/6464/5782/3084/6654/10718/1956/685/1950/2066/5581 22 Bunyavirus R-HSA-389977 Post-chaperonin tubulin folding pathway 22/4506 22/10654 5.824384104792016e-9 3.0638458272000265e-8 1.445974206750749e-8 51807/10381/7278/7846/113457/81027/402/79861/6903/10376/6904/84617/10382/7277/347733/10383/84790/7280/112714/6902/6905/1155 22 Bunyavirus R-HSA-168898 Toll-like Receptor Cascades 101/4506 155/10654 6.379970288852866e-9 3.343488188970261e-8 1.5779507046034988e-8 8454/3725/10695/9252/4790/7321/1785/6280/4792/1432/2244/3654/6196/1759/5518/7187/1386/6197/7334/3551/51231/7314/5515/54106/11035/8945/1326/5606/11213/8737/29110/5594/6271/4214/23118/841/8517/5528/7323/5970/9261/5519/5598/6195/10454/3661/6233/51311/10010/2266/2353/2243/8772/5781/30849/4791/671/3665/351/7184/3684/8411/330/51295/7098/338/79155/6279/26052/64127/5602/3656/695/7189/81622/7311/9641/6416/51284/5595/5516/1147/1845/6885/5604/10392/6500/7099/4615/7316/5289/4793/5775/7322/329/23291/5609/5599/7097/3929/3689 101 Bunyavirus R-HSA-194315 Signaling by Rho GTPases 252/4506 455/10654 6.458609592769926e-9 3.372023135700852e-8 1.5914176997757556e-8 55839/11130/64837/71/6249/5579/392/9735/7531/5526/51807/10971/5578/9212/347688/613/3798/1894/388/7533/2810/147841/348995/10381/57122/6280/7278/1780/23122/3688/5048/8655/10094/23279/1432/2017/2491/9138/7846/113457/23365/79784/9475/1060/81027/4628/57449/11004/8976/1855/2885/6093/9184/8826/10499/5518/26084/23332/3071/10726/81930/5062/55746/2665/5879/5515/9181/26999/25/79682/1072/10403/79861/4638/25936/4659/10093/1856/10006/4771/389/5594/29127/64105/7534/332/5528/6453/9828/6714/55114/79902/3796/5519/81565/999/89953/396/10810/91687/11243/10376/23002/57584/11113/83540/7410/5580/7409/9055/1857/128239/4649/23191/7514/51306/147700/54820/1729/5217/6396/1535/801/64946/9793/30849/10109/5586/140735/9886/2664/5500/10787/4221/805/3831/5170/84617/4928/5590/5903/653361/5747/80776/1783/401541/2316/7532/27237/10382/7074/10627/79172/7277/79980/6232/5501/10152/6279/10092/9183/4650/10163/1062/699/347733/752/22919/55845/5063/3895/5529/51143/998/695/10788/6654/10097/367/10383/5347/387/60/84790/84643/5058/4660/7280/4629/7529/5595/1778/5516/81929/3984/54908/55143/1495/1499/5525/4690/1058/991/79019/4627/10928/80152/10458/1063/3985/54763/1027/1080/23421/55920/79023/112714/1781/9824/10398/4085/5289/5585/5216/4168/10552/81624/55166/9826/8936/4637/995/79003/391/23221/23028/89941/2/90627/5527/10096/701/23380/9928/29941/3799/103910/5296/5300/10095/1536/10672 252 Bunyavirus R-HSA-180746 Nuclear import of Rev protein 30/4506 33/10654 6.593465604759347e-9 3.429586213818854e-8 1.6185844473584416e-8 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/3837/81929/9631/79023/23636/53371/9688/8480 30 Bunyavirus R-HSA-109606 Intrinsic Pathway for Apoptosis 43/4506 53/10654 7.490061804598703e-9 3.881466972345945e-8 1.8318484163076465e-8 7531/55075/10971/7533/2810/1869/8655/836/840/7159/637/7027/5594/841/7534/4836/598/10000/708/3002/7157/331/317/140735/1029/572/7532/6774/56616/8626/208/7161/7529/5595/5533/596/10018/842/207/54205/5534/581/5599 43 Bunyavirus R-HSA-166166 MyD88-independent TLR4 cascade 70/4506 99/10654 8.803005504738802e-9 4.5281880714412876e-8 2.137066785963003e-8 8454/3725/9252/4790/7321/4792/1432/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/11035/8945/1326/5606/8737/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/6195/10454/3661/6233/10010/2353/8772/5781/4791/3665/351/330/79155/64127/5602/3656/7189/7311/9641/6416/5595/5516/1147/1845/6885/5604/10392/6500/7099/7316/4793/7322/329/23291/5609/5599 70 Bunyavirus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 70/4506 99/10654 8.803005504738802e-9 4.5281880714412876e-8 2.137066785963003e-8 8454/3725/9252/4790/7321/4792/1432/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/11035/8945/1326/5606/8737/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/6195/10454/3661/6233/10010/2353/8772/5781/4791/3665/351/330/79155/64127/5602/3656/7189/7311/9641/6416/5595/5516/1147/1845/6885/5604/10392/6500/7099/7316/4793/7322/329/23291/5609/5599 70 Bunyavirus R-HSA-8939211 ESR-mediated signaling 136/4506 223/10654 1.0661301162208807e-8 5.463916845632013e-8 2.578681589156542e-8 5295/2788/374/3725/4893/857/7764/7031/2770/7039/27327/5431/5435/5433/1509/4609/1387/8312/2782/5439/192669/10499/1386/4343/3845/904/7392/3265/8877/2773/2787/1839/5290/6801/5594/2069/10681/5481/5438/4313/1655/6667/2792/6714/2099/8850/10000/2785/595/2783/2784/2771/7514/1025/2353/26523/801/2791/2957/805/5170/2963/3838/5434/5590/6464/7090/5241/5747/5436/3315/200845/5885/57678/2962/8503/10524/8243/4602/2786/208/3326/23030/6908/1956/5536/3169/858/23189/5432/3480/10728/5595/7528/27161/596/5440/685/54331/4435/2309/59345/8204/5430/207/2625/1027/51764/94235/5441/10735/192670/2100/1950/55970/4314/2289/7391/2958/5437/2793/3320/2033/4846/9126/3065/2066/861/23028/10498/5296/3276/8202/8648/2288/2790 136 Bunyavirus R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 27/4506 29/10654 1.110860721956141e-8 5.651605278857155e-8 2.6672606654728708e-8 113802/5431/5435/5433/55124/84944/5439/11022/91646/5438/56165/54514/5434/5436/122402/221400/143689/5432/5440/8468/5430/5441/5437/3320/54456/9271/136991 27 Bunyavirus R-HSA-8863795 Downregulation of ERBB2 signaling 27/4506 29/10654 1.110860721956141e-8 5.651605278857155e-8 2.6672606654728708e-8 26469/2064/145957/4145/9542/7314/1839/2065/2069/9101/10000/6233/5782/3084/208/10718/7311/1956/11140/8065/685/10273/207/7316/1950/3320/2066 27 Bunyavirus R-HSA-416572 Sema4D induced cell migration and growth-cone collapse 21/4506 21/10654 1.3808400487458993e-8 6.999603738006486e-8 3.3034450926935386e-8 388/2064/23365/79784/9475/4628/6093/10507/27289/389/5364/10627/387/4629/3984/4627/3985/10398/9826/4637/103910 21 Bunyavirus R-HSA-69190 DNA strand elongation 29/4506 32/10654 1.4255608185631985e-8 7.200115148830068e-8 3.398075940511057e-8 2237/5982/5422/4174/84515/84296/6117/5558/6118/64785/3978/5557/5985/4175/5984/23649/5424/4172/8318/4173/5425/5111/6119/51659/5983/4176/9837/4171/5981 29 Bunyavirus R-HSA-1643713 Signaling by EGFR in Cancer 24/4506 25/10654 1.5414131598660904e-8 7.757147815354982e-8 3.6609660836644756e-8 5295/374/4893/5335/7039/2885/3845/3265/7314/1839/5290/2069/6233/6464/6654/7311/1956/2549/11140/685/7316/1950/867/3320 24 Bunyavirus R-HSA-70326 Glucose metabolism 65/4506 91/10654 1.565090499964847e-8 7.847971787593513e-8 3.703830225210259e-8 23165/7167/5313/2806/8402/5211/348995/57122/3099/6576/23511/23279/5106/23225/9972/5518/4191/8021/55746/5515/2597/5567/1468/10762/5528/79902/26330/5519/9883/226/2821/8604/5208/6396/129401/230/5105/4928/5903/55706/7175/2203/2805/4927/5566/2023/4190/8086/5516/81929/9631/5091/5315/79023/23636/5214/53371/5230/10165/3098/9688/5213/92579/8480/5223 65 Bunyavirus R-HSA-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle 31/4506 35/10654 1.576839128283092e-8 7.85040623152368e-8 3.7049791548004986e-8 9761/811/6400/51009/7314/9695/5700/10956/79139/91445/11253/80267/6233/23193/267/7841/6048/821/56886/10206/84447/2923/7311/55768/7844/7316/5589/7415/51035/11236/5887 31 Bunyavirus R-HSA-8953750 Transcriptional Regulation by E2F6 31/4506 35/10654 1.576839128283092e-8 7.85040623152368e-8 3.7049791548004986e-8 80314/6045/80012/11335/1869/1911/5928/10138/23512/672/6241/5888/83746/7027/2146/1876/8726/8409/7703/317/23429/84108/5931/1111/648/23468/23269/8317/4149/5932/10919 31 Bunyavirus R-HSA-162587 HIV Life Cycle 98/4506 152/10654 2.4067562472156044e-8 1.193956657871371e-7 5.634847928487555e-8 23165/51652/2237/7852/27243/6874/348995/57122/55048/3981/5431/23511/5435/5433/23279/23327/29082/8732/23225/5439/3836/9972/8021/11198/904/51497/55746/7314/25978/7518/10015/5438/3978/10762/79720/4836/79902/11168/9883/51510/5478/6233/7514/1025/6396/129401/6829/2957/4928/2963/5434/5903/55706/7175/5436/6878/920/4331/4927/8148/2962/128866/5901/8086/7311/6880/6908/7251/2547/2961/5432/22916/6917/81929/5440/9631/3159/5430/7520/6749/79023/5441/23636/4686/7316/6872/53371/9688/8731/6879/9150/9525/2958/5437/8815/1022/8178/8480 98 Bunyavirus R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 73/4506 106/10654 2.570588807806251e-8 1.270709502865927e-7 5.997081018584946e-8 374/85439/8674/4738/7039/1212/950/554/10980/3482/408/10987/6456/30011/2885/163/7314/1839/161/7018/10618/1856/9892/2060/2069/1601/6453/55707/8301/9146/4074/10920/29979/6233/6844/1213/1211/29924/1175/1173/6857/84251/409/160/338/920/22905/2873/7311/1956/8533/8673/50618/51138/9318/685/1080/29978/58513/7316/1950/64708/3949/867/9341/915/917/115548/143425/3575/154/10254/50813 73 Bunyavirus R-HSA-5674135 MAP2K and MAPK activation 34/4506 40/10654 3.004917927636303e-8 1.480160986263253e-7 6.985581940757632e-8 4893/71/84292/5605/5037/2244/3690/408/5894/8826/4140/3845/3265/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/28956/283455/409/673/7450/60/7529/5595/5604/8649/5906 34 Bunyavirus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 65/4506 92/10654 3.137301362210975e-8 1.5399289080711614e-7 7.267655120021718e-8 5563/9156/1459/7486/6874/9212/5982/1460/11200/472/1457/6790/4194/1432/4683/84126/8900/672/6117/11198/7314/6118/890/5985/7157/5984/6233/5884/5810/26155/8445/204851/6878/580/11073/641/8148/6119/3364/5571/10524/6794/1111/7311/5562/6880/6908/5983/5564/1020/1017/9891/5883/10111/22974/6749/545/7316/6872/6879/112858/5932/8851/5300/4193 65 Bunyavirus R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 20/4506 20/10654 3.2732619434605095e-8 1.589870086823676e-7 7.503351236614042e-8 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Bunyavirus R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 20/4506 20/10654 3.2732619434605095e-8 1.589870086823676e-7 7.503351236614042e-8 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Bunyavirus R-HSA-5627117 RHO GTPases Activate ROCKs 20/4506 20/10654 3.2732619434605095e-8 1.589870086823676e-7 7.503351236614042e-8 388/79784/9475/4628/6093/1072/4659/389/5500/10627/387/5058/4660/4629/3984/4627/3985/10398/4637/103910 20 Bunyavirus R-HSA-5627123 RHO GTPases activate PAKs 23/4506 24/10654 3.5129349204902496e-8 1.7003580830428499e-7 8.024796510622829e-8 2017/79784/4628/5062/5879/4638/4659/4771/801/5500/805/2316/10627/5063/998/5058/4660/4629/3984/4627/10398/4637/103910 23 Bunyavirus R-HSA-73893 DNA Damage Bypass 39/4506 48/10654 3.53068436745013e-8 1.703035989005357e-7 8.037434819363803e-8 56852/5982/9978/25898/6117/55666/7314/51514/6118/9636/51455/5985/5984/6233/5424/8451/124739/54107/7706/8450/5425/5111/6119/83932/5427/1642/5429/9246/7311/5983/56655/7320/7316/5426/9100/10459/7415/7398/5981 39 Bunyavirus R-HSA-983231 Factors involved in megakaryocyte development and platelet production 106/4506 168/10654 3.606365812242798e-8 1.7335427387125723e-7 8.181410644833935e-8 9927/23764/64837/11311/11127/51807/347688/3798/10381/7278/832/285643/3043/10112/64147/3717/7846/113457/81027/11004/10749/4097/1794/4778/7465/81930/5879/25/113220/79861/30846/5868/3797/23186/5567/29127/3045/55605/3796/124602/55614/89953/56992/10376/3066/7157/3835/147700/3833/9493/3660/9732/3831/84617/85440/9585/10382/830/3832/7277/3046/1793/23303/2623/3659/5566/26153/1062/146909/347733/90990/4602/998/7975/5577/23046/10383/24137/60/25942/84790/84643/1020/22920/7280/829/55582/11216/1017/23468/9371/8165/23095/2625/3047/3048/112714/5576/547/3065/23028/3834/55083/3799/10938/221458 106 Bunyavirus R-HSA-382556 ABC-family proteins mediated transport 71/4506 103/10654 3.754572642890364e-8 1.7985822213708477e-7 8.48836282078668e-8 5689/1965/5682/8714/23/143471/91319/5705/5709/5695/5711/5683/5699/6400/5702/51009/4363/5696/5691/7314/5718/5700/122706/5707/10956/79139/91445/23198/9861/8894/5698/215/5692/5713/5710/5719/10613/6233/27248/1968/6048/5706/10257/335/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/5824/1244/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 71 Bunyavirus R-HSA-388841 Costimulation by the CD28 family 52/4506 70/10654 5.167650437147372e-8 2.467022160747752e-7 1.1643048028900892e-7 5295/5526/3115/3113/3117/2534/2885/2475/5518/3127/5062/5879/5515/1326/5290/57761/3126/5528/9020/6714/5519/29126/10000/1445/7525/7409/3932/5781/253260/3120/5170/3123/3122/920/64223/8503/4067/5063/5529/998/208/3125/5058/5516/9402/5525/3119/207/915/917/5527/5296 52 Bunyavirus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 49/4506 65/10654 5.668262486951383e-8 2.6876047302075607e-7 1.2684081827227407e-7 2074/5982/5431/5435/9978/5433/5439/6117/7314/6118/5438/3978/5985/5984/6233/7874/5424/8451/10450/5434/5436/7515/54107/8450/4331/5425/5111/6119/5427/1161/1642/7311/3980/5983/5432/56655/6917/5440/27339/5430/5441/7316/5426/5437/2033/56949/9716/5981/1022 49 Bunyavirus R-HSA-9614085 FOXO-mediated transcription 49/4506 65/10654 5.668262486951383e-8 2.6876047302075607e-7 1.2684081827227407e-7 2308/857/65018/356/10971/7295/2810/694/84676/4089/1387/4088/10628/4801/3630/56729/23411/7534/847/3484/8850/10000/3066/604/5105/7532/4303/23410/4287/4800/2908/6794/6648/4087/208/25942/7529/2309/10018/4802/207/1027/6720/1649/1026/2033/3065/91584/10891 49 Bunyavirus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 27/4506 30/10654 6.60110410867757e-8 3.108763218748829e-7 1.467172854880328e-7 56852/5982/9978/6117/7314/51514/6118/5985/5984/6233/5424/8451/54107/8450/5425/5111/6119/5427/1642/7311/5983/56655/7320/7316/5426/7398/5981 27 Bunyavirus R-HSA-180786 Extension of Telomeres 27/4506 30/10654 6.60110410867757e-8 3.108763218748829e-7 1.467172854880328e-7 2237/5982/5422/6117/5558/6118/3978/5557/5985/5984/23649/8607/5424/55651/54107/5425/5111/6119/5427/55135/5983/56655/7015/10856/5426/1736/5981 27 Bunyavirus R-HSA-177243 Interactions of Rev with host cellular proteins 31/4506 36/10654 6.731673468882664e-8 3.1384457577332555e-7 1.4811814532834592e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/3837/81929/9631/79023/23636/53371/9688/8480 31 Bunyavirus R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 31/4506 36/10654 6.731673468882664e-8 3.1384457577332555e-7 1.4811814532834592e-7 71/10094/8976/2885/3071/5879/26999/25/10093/10006/5594/10810/23191/10109/10787/5747/10152/10092/10163/55845/998/695/10097/60/5595/4690/10458/10552/8936/10096/10095 31 Bunyavirus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 31/4506 36/10654 6.731673468882664e-8 3.1384457577332555e-7 1.4811814532834592e-7 4893/71/5605/5037/2244/3690/408/5894/8826/4140/3845/3265/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/283455/409/673/7450/60/7529/5595/5604/5906 31 Bunyavirus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 19/4506 19/10654 7.758221700178865e-8 3.557552976989913e-7 1.6789780341453571e-007 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Bunyavirus R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 19/4506 19/10654 7.758221700178865e-8 3.557552976989913e-7 1.6789780341453571e-007 11065/7321/8697/51529/29945/51434/29882/996/51433/119504/7324/64682/246184/8881/10393/51343/25906/991/8556 19 Bunyavirus R-HSA-176412 Phosphorylation of the APC/C 19/4506 19/10654 7.758221700178865e-8 3.557552976989913e-7 1.6789780341453571e-007 11065/7321/8697/51529/29945/51434/29882/996/983/51433/119504/7324/64682/246184/8881/891/10393/25906/5347 19 Bunyavirus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 19/4506 19/10654 7.758221700178865e-8 3.557552976989913e-7 1.6789780341453571e-007 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Bunyavirus R-HSA-77595 Processing of Intronless Pre-mRNAs 19/4506 19/10654 7.758221700178865e-8 3.557552976989913e-7 1.6789780341453571e-007 51585/81608/1477/53981/11051/8106/1478/23283/10914/10898/51692/22916/1479/79869/29894/4686/8189/10978/55339 19 Bunyavirus R-HSA-6784531 tRNA processing in the nucleus 44/4506 57/10654 8.106167530864372e-8 3.704917225581946e-7 1.7485262145954212e-7 23165/10557/348995/57122/23511/23279/11102/23225/79074/9972/8021/10799/55746/60528/54913/10762/1478/79902/9883/10556/1653/6396/129401/79897/4928/5903/55706/7175/339487/4927/10898/5901/8086/81929/9631/29894/79023/23636/53371/10978/283742/9688/51493/8480 44 Bunyavirus R-HSA-449147 Signaling by Interleukins 250/4506 461/10654 9.002120546407344e-8 4.100966026696679e-7 1.9354404339541076e-7 5295/8454/6804/7124/2308/5689/3725/7291/9252/4790/5682/1511/26469/5657/356/23529/8878/6624/5743/3091/143471/3383/5705/6657/3313/3688/4985/5709/6175/9978/5695/1435/4792/7133/4609/5898/5711/1432/3558/3717/4088/836/5683/200081/2534/5699/3181/5702/4001/3654/2885/8660/6196/3594/9846/6347/5518/1386/6382/7040/6197/4282/7334/3312/1399/3551/3569/5062/5696/5691/51231/4692/7314/5515/5718/8945/1326/1072/5290/3667/6627/5606/9049/11213/7412/5700/122706/5707/27250/3911/29110/5594/4582/23198/23118/9987/8517/6778/7534/332/5528/4313/3185/5970/9261/3718/9861/5519/5598/598/5698/5692/5713/2335/595/6195/5710/3458/10454/7157/5478/5719/6233/7525/6844/7409/2353/604/3932/7076/302/8835/552900/6777/6773/7297/5781/4791/56300/351/6464/6597/5782/7184/6775/3684/54472/821/5706/301/4478/6616/79155/6774/920/6850/5780/5714/6772/5566/64127/8503/3552/5688/79923/5687/4067/29760/3636/5708/5602/3656/5771/998/6648/7189/6654/5704/3716/7311/6888/2185/5694/6416/3586/829/5595/5516/6095/1147/1845/596/5684/5720/6885/2309/5604/4215/10392/207/5292/7422/5690/2625/5717/9491/6500/25930/10197/4615/1436/7316/10213/3560/27179/4314/3055/1026/4793/5775/6647/5715/5701/867/6950/23291/5685/3320/5686/4843/5306/5609/1398/5716/3575/4507/5896/5296/3687/5599/5784/7431/375/3929/4170/5693/3689/5721/5724/5034 250 Bunyavirus R-HSA-195721 Signaling by WNT 187/4506 331/10654 9.052008493621456e-8 4.110260534237235e-7 1.9398269530304857e-7 2788/8454/56998/9070/5689/857/5579/5682/1459/5526/1452/5578/1212/5929/5582/27327/1460/55737/143471/5705/6657/2775/8452/5530/55366/5709/9978/5695/1457/3709/4609/5711/1387/5683/324/5699/8724/8312/2782/5702/192669/1855/6932/163/5518/4343/5593/25776/3845/6659/80351/5696/5691/4920/7314/5879/5515/2787/5718/51176/8945/7476/161/79971/5700/122706/5707/1856/1454/23198/10681/9101/8395/7534/5528/7091/83439/2792/59349/9861/81847/5519/2932/5698/5692/5713/2785/2783/23002/2784/5710/8313/5719/6233/1857/7514/1213/3710/1211/7089/331/8607/1175/26523/801/2791/4221/805/123169/1173/144165/7090/6597/864/4772/4041/409/79577/5706/160/8658/5714/6934/10524/5688/5687/607/5708/5529/7088/2786/208/57680/5704/7311/387/5694/5516/57154/27161/815/5684/8295/5720/54331/7015/6885/1487/1499/5525/59345/139285/207/5690/5717/9491/50855/6500/51764/94235/3708/10197/192670/64750/7316/10213/55970/5216/5715/5701/2793/1455/5685/5686/2033/54894/5534/3065/23513/5527/5716/23072/9736/5693/5721/6259/2790 187 Bunyavirus R-HSA-450294 MAP kinase activation 48/4506 64/10654 1.0210375730710593e-7 4.6211895352631713e-7 2.180958589095735e-7 8454/3725/9252/4790/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/8945/1326/5606/5594/23118/8517/5528/9261/5519/5598/6195/10454/6233/2353/79155/64127/5602/3656/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/7316/23291/5609/5599 48 Bunyavirus R-HSA-111465 Apoptotic cleavage of cellular proteins 32/4506 38/10654 1.2270265062593732e-7 5.535517636652319e-7 2.6124733994621306e-7 2339/660/836/324/4001/6709/6093/840/2934/22985/63967/841/7082/5339/5317/28988/10134/999/5588/5580/1828/5747/118/1829/8428/1832/4000/51765/1499/329/4137/7431 32 Bunyavirus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 84/4506 129/10654 1.2457789580140533e-7 5.601986669263194e-7 2.6438432895035087e-7 8454/3725/9252/4790/7321/1785/4792/1432/3654/6196/1759/5518/7187/1386/6197/7334/3551/51231/7314/5515/11035/8945/1326/5606/11213/8737/29110/5594/4214/23118/841/8517/5528/7323/5970/9261/5519/5598/6195/10454/3661/6233/10010/2353/8772/5781/4791/671/3665/351/3684/330/51295/79155/26052/64127/5602/3656/695/7189/7311/9641/6416/5595/5516/1147/1845/6885/5604/10392/6500/7099/4615/7316/4793/5775/7322/329/23291/5609/5599/7097/3929/3689 84 Bunyavirus R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 28/4506 32/10654 1.4602375670767385e-7 6.545244914806989e-7 3.089011607456293e-7 2788/408/2768/2782/2776/2787/5594/10681/2792/6714/2785/2783/2784/2151/2791/2147/409/2786/5595/54331/59345/51764/94235/55970/2767/2793/2790/10672 28 Bunyavirus R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 21/4506 22/10654 1.8147274452346456e-7 8.082204660246313e-7 3.814375830743748e-7 3725/7531/356/7001/4001/826/823/2801/993/351/6648/1020/4000/994/2309/10018/831/824/995/8851/5052 21 Bunyavirus R-HSA-8863678 Neurodegenerative Diseases 21/4506 22/10654 1.8147274452346456e-7 8.082204660246313e-7 3.814375830743748e-7 3725/7531/356/7001/4001/826/823/2801/993/351/6648/1020/4000/994/2309/10018/831/824/995/8851/5052 21 Bunyavirus R-HSA-190840 Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane 18/4506 18/10654 1.838601738037037e-7 8.13654229467819e-7 3.8400203384232187e-7 51807/347688/2697/10381/7278/7846/113457/81027/79861/10376/84617/10382/7277/347733/10383/84790/7280/112714 18 Bunyavirus R-HSA-8964315 G beta:gamma signalling through BTK 18/4506 18/10654 1.838601738037037e-7 8.13654229467819e-7 3.8400203384232187e-7 2788/2782/2787/10681/2792/2785/2783/2784/2791/695/2786/54331/59345/51764/94235/55970/2793/2790 18 Bunyavirus R-HSA-5628897 TP53 Regulates Metabolic Genes 60/4506 86/10654 2.18010331319672e-7 9.617291198089329e-7 4.5388559984941715e-7 5563/7531/10971/9997/27327/7295/7533/2810/7001/6341/192669/2475/51204/4343/7296/9377/1329/2936/7249/27244/7534/1351/2821/10000/54541/7157/50484/9167/26523/2744/57521/28956/83667/7532/1345/84987/64223/5571/10128/25824/8626/208/5562/1340/4697/5564/7248/7529/27161/207/192670/2539/54205/143686/1350/8649/5728/1349/1327/5052 60 Bunyavirus R-HSA-373755 Semaphorin interactions 48/4506 65/10654 2.3035166066030425e-7 1.0129659777932623e-6 4.780667040102612e-7 5361/388/2064/8829/3688/23365/79784/2534/9475/1808/4628/6093/10507/5362/5062/5879/1400/27289/23396/1072/7094/389/10371/5364/2932/55558/10570/10627/4233/5063/3326/387/5058/1020/4629/3984/4627/3985/1809/10398/9826/4637/3320/91584/56896/103910/8851/2242 48 Bunyavirus R-HSA-400685 Sema4D in semaphorin signaling 23/4506 25/10654 2.618543516766806e-7 1.1478772523185305e-6 5.417377351801568e-7 388/2064/23365/79784/9475/4628/6093/10507/5879/27289/389/5364/10627/4233/387/4629/3984/4627/3985/10398/9826/4637/103910 23 Bunyavirus R-HSA-165054 Rev-mediated nuclear export of HIV RNA 29/4506 34/10654 2.818950565196614e-7 1.2318548864840377e-6 5.813707649720785e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/81929/9631/79023/23636/53371/9688/8480 29 Bunyavirus R-HSA-166520 Signaling by NTRKs 68/4506 101/10654 2.9991078882095803e-7 1.3064863738012986e-6 6.165929046483512e-7 5295/9252/4893/5335/1785/5605/5898/1432/2534/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5879/5515/5607/161/5290/3667/5594/5528/9261/6714/5519/5598/4914/6195/1213/1211/1175/5781/1173/5800/6464/7074/160/673/6774/26052/5802/6654/387/2549/1020/4916/7529/5595/5516/1845/4915/5604/10817/57498/4803/1398/5906/8851/5296/581 68 Bunyavirus R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 27/4506 31/10654 3.0418083785402164e-7 1.3168574160512613e-6 6.214874915291387e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/79023/23636/53371/9688/8480 27 Bunyavirus R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 27/4506 31/10654 3.0418083785402164e-7 1.3168574160512613e-6 6.214874915291387e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/79023/23636/53371/9688/8480 27 Bunyavirus R-HSA-2682334 EPH-Ephrin signaling 63/4506 92/10654 3.189494939904693e-7 1.3765188688009727e-6 6.496445616556732e-7 71/1212/23385/2051/10094/79784/2047/2534/9475/4628/8976/6093/163/1759/3265/5062/5879/1072/161/10093/5921/2046/6453/4313/2041/102/6714/2043/7525/7410/1213/1211/1175/10109/5663/64283/1173/5747/7074/10627/160/10092/4067/5063/6386/998/10097/387/60/5058/4629/3984/28964/4627/3985/6383/10398/10552/4637/10096/103910/10095/1969 63 Bunyavirus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 37/4506 47/10654 3.6715088166321665e-7 1.5796553365386544e-6 7.455142983739782e-7 8454/79718/892/3091/9978/9759/4609/22938/1387/7314/79885/2648/9734/55869/51564/3280/10013/83933/7091/8850/3066/6233/7089/7090/10014/7088/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 37 Bunyavirus R-HSA-5218921 VEGFR2 mediated cell proliferation 20/4506 21/10654 4.112169983775303e-7 1.7638046022716224e-6 8.324230736387253e-7 4893/5335/5579/5578/3709/3845/3265/8877/5921/6714/5580/3791/3710/801/805/5170/5590/7422/3708/10768 20 Bunyavirus R-HSA-70171 Glycolysis 51/4506 71/10654 4.1740264344817675e-7 1.784844432413369e-6 8.423527676948998e-7 23165/7167/5313/5211/348995/57122/3099/23511/23279/23225/9972/5518/8021/55746/5515/2597/5567/10762/5528/79902/26330/5519/9883/226/2821/5208/6396/129401/230/4928/5903/55706/7175/4927/5566/2023/8086/5516/81929/9631/5315/79023/23636/5214/53371/5230/3098/9688/5213/8480/5223 51 Bunyavirus R-HSA-187037 Signaling by NTRK1 (TRKA) 56/4506 80/10654 4.6309974493111614e-7 1.974192796434177e-6 9.317152441073478e-7 5295/9252/4893/5335/1785/5605/5898/1432/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5515/5607/161/5290/3667/5594/5528/9261/6714/5519/5598/4914/6195/1213/1211/1175/1173/6464/160/673/6774/26052/6654/387/7529/5595/5516/1845/4915/5604/57498/4803/1398/5906/5296 56 Bunyavirus R-HSA-5654738 Signaling by FGFR2 52/4506 73/10654 4.953470093603332e-7 2.105224789781416e-6 9.935554584409765e-7 5295/4893/5335/54845/5431/5435/5433/5439/7072/2885/7073/5518/3845/3265/7314/5515/5290/5594/8074/5438/3185/6714/4670/6233/5781/5725/2963/5434/6464/5436/673/2962/80004/6654/7311/2549/5432/22916/5595/5516/5440/23543/5430/3178/10817/5441/4686/7316/867/5437/2255/3187 52 Bunyavirus R-HSA-177929 Signaling by EGFR 38/4506 49/10654 5.121287981575805e-7 2.1699317466008127e-6 1.0240937413165505e-6 5295/374/4893/5335/7039/6456/30011/2885/3845/3265/5829/7314/1839/5290/2060/2069/102/6714/9146/1445/6233/29924/5781/6464/5782/998/6654/7311/1956/2549/685/26018/58513/7316/1950/867/5774/10254 38 Bunyavirus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 46/4506 63/10654 7.141733438295251e-7 3.0168413372677518e-6 1.423790557873854e-6 55718/4790/5435/4792/3428/1387/22954/1660/3551/7314/11035/8737/29110/81844/8517/6778/5970/3661/6233/11128/4791/9533/3665/5434/10623/23220/7098/5591/7311/171568/2547/1147/170506/5440/6737/1499/7520/147945/5441/51082/4615/7316/55703/4793/5437/2033 46 Bunyavirus R-HSA-5625900 RHO GTPases activate CIT 19/4506 20/10654 9.297245707782739e-7 3.903723047183476e-6 1.8423521139391924e-6 388/79784/4628/5879/4659/389/11113/9055/5500/10627/387/4660/4629/4627/1027/10398/4637/9928/103910 19 Bunyavirus R-HSA-8964616 G beta:gamma signalling through CDC42 19/4506 20/10654 9.297245707782739e-7 3.903723047183476e-6 1.8423521139391924e-6 2788/2782/2787/10681/2792/2785/2783/2784/2791/998/2786/5058/54331/59345/51764/94235/55970/2793/2790 19 Bunyavirus R-HSA-1963640 GRB2 events in ERBB2 signaling 16/4506 16/10654 1.03221666196967e-6 4.269762690758813e-6 2.0151035881025887e-6 4893/2064/145957/9542/2885/3845/3265/1839/2069/3084/6654/10718/1956/685/1950/2066 16 Bunyavirus R-HSA-1963642 PI3K events in ERBB2 signaling 16/4506 16/10654 1.03221666196967e-6 4.269762690758813e-6 2.0151035881025887e-6 5295/2064/145957/9542/2885/1839/5290/2065/2069/3084/10718/1956/2549/685/1950/2066 16 Bunyavirus R-HSA-399954 Sema3A PAK dependent Axon repulsion 16/4506 16/10654 1.03221666196967e-6 4.269762690758813e-6 2.0151035881025887e-6 5361/8829/2534/5362/5062/5879/1072/10371/55558/5063/3326/5058/3984/3320/91584/2242 16 Bunyavirus R-HSA-399956 CRMPs in Sema3A signaling 16/4506 16/10654 1.03221666196967e-6 4.269762690758813e-6 2.0151035881025887e-6 5361/8829/2534/1808/5362/1400/10371/2932/55558/10570/1020/1809/91584/56896/8851/2242 16 Bunyavirus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 16/4506 16/10654 1.03221666196967e-6 4.269762690758813e-6 2.0151035881025887e-6 8454/4790/3551/7314/8945/1326/8517/6233/79155/7311/6416/1147/5604/6500/7316/23291 16 Bunyavirus R-HSA-392518 Signal amplification 27/4506 32/10654 1.158229076044304e-6 4.77683826037207e-6 2.254416607062255e-6 2788/2770/1432/2782/2776/2773/2787/10681/2792/6714/2785/2783/2784/2771/2791/6915/2786/5321/54331/59345/51764/94235/55970/2767/2793/2790/10672 27 Bunyavirus R-HSA-428930 Thromboxane signalling through TP receptor 21/4506 23/10654 1.2477782327366563e-6 5.130981877389082e-6 2.4215537818984946e-6 2788/2782/2776/2787/10681/2792/2785/2783/2784/2791/6915/2786/54331/59345/51764/94235/55970/2767/2793/2790/10672 21 Bunyavirus R-HSA-9619483 Activation of AMPK downstream of NMDARs 25/4506 29/10654 1.3019721953612824e-6 5.338086000981258e-6 2.5192960436557326e-6 5563/51807/347688/10381/7278/7846/113457/81027/79861/10376/801/805/84617/10382/7277/10645/5571/347733/5562/10383/84790/5564/7280/112714/4137 25 Bunyavirus R-HSA-901042 Calnexin/calreticulin cycle 23/4506 26/10654 1.3543464842005477e-6 5.536536653887283e-6 2.612954322041495e-6 811/6400/51009/7314/9695/10956/91445/11253/80267/6233/23193/267/6048/821/56886/10206/84447/2923/7311/7844/7316/5589/11236 23 Bunyavirus R-HSA-170834 Signaling by TGF-beta Receptor Complex 51/4506 73/10654 1.6532216470103215e-6 6.738570105065463e-6 3.1802509368465715e-6 892/7321/4738/8239/4609/4089/22938/23327/4088/5499/9110/7040/904/7314/5054/7027/6497/51592/7323/6667/11171/7046/2280/9958/9040/6233/7514/1025/57530/5500/4221/5590/5501/1874/142/4087/7048/7311/387/57154/51377/10273/50855/64750/54778/7316/9611/867/3065/56288/25937 51 Bunyavirus R-HSA-3928662 EPHB-mediated forward signaling 33/4506 42/10654 1.733513952606855e-6 7.045243294268094e-6 3.324984564613425e-6 71/2051/10094/2047/2534/9475/8976/6093/3265/5879/1072/10093/5921/6453/6714/7525/10109/64283/5747/7074/10092/4067/998/10097/387/60/5058/3984/3985/6383/10552/10096/10095 33 Bunyavirus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 64/4506 97/10654 1.9707254762082576e-6 7.986021261146253e-6 3.768982321389722e-6 8454/3725/9252/4790/4792/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/54106/8945/1326/5606/5594/4214/23118/8517/5528/5970/9261/5519/5598/6195/10454/6233/51311/2353/30849/4791/3665/351/8411/51295/79155/64127/5602/3656/7189/7311/6416/51284/5595/5516/1147/1845/6885/5604/10392/6500/7099/4615/7316/5289/4793/23291/5609/5599 64 Bunyavirus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 40/4506 54/10654 2.0708027855100383e-6 8.36724371884346e-6 3.948899285869639e-6 2074/5431/5435/9978/5433/10980/5439/10987/7314/5438/10920/6233/7874/8451/10450/5434/5436/8450/4331/1161/1642/2873/7311/8533/5432/51138/9318/6917/5440/27339/5430/5441/7316/64708/5437/2033/56949/9716/1022/50813 40 Bunyavirus R-HSA-110320 Translesion Synthesis by POLH 18/4506 19/10654 2.0968633962381797e-6 8.399504524011558e-6 3.964124690407933e-6 5982/25898/6117/55666/7314/6118/5985/5984/6233/5111/6119/83932/5429/7311/5983/7316/7415/5981 18 Bunyavirus R-HSA-190872 Transport of connexons to the plasma membrane 18/4506 19/10654 2.0968633962381797e-6 8.399504524011558e-6 3.964124690407933e-6 51807/347688/2697/10381/7278/7846/113457/81027/79861/10376/84617/10382/7277/347733/10383/84790/7280/112714 18 Bunyavirus R-HSA-392851 Prostacyclin signalling through prostacyclin receptor 18/4506 19/10654 2.0968633962381797e-6 8.399504524011558e-6 3.964124690407933e-6 2788/2782/2787/10681/2792/2785/2783/2784/2791/2786/54331/59345/51764/94235/55970/2778/2793/2790 18 Bunyavirus R-HSA-162599 Late Phase of HIV Life Cycle 86/4506 139/10654 2.283560803566638e-6 9.121156905936658e-6 4.304706687465387e-6 23165/51652/27243/6874/348995/57122/55048/5431/23511/5435/5433/23279/23327/29082/8732/23225/5439/9972/8021/11198/904/51497/55746/7314/25978/10015/5438/10762/79720/4836/79902/9883/51510/5478/6233/7514/1025/6396/129401/6829/2957/4928/2963/5434/5903/55706/7175/5436/6878/4331/4927/8148/2962/128866/5901/8086/7311/6880/6908/7251/2961/5432/22916/6917/81929/5440/9631/5430/6749/79023/5441/23636/4686/7316/6872/53371/9688/8731/6879/9150/9525/2958/5437/1022/8178/8480 86 Bunyavirus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 31/4506 39/10654 2.296860522863996e-6 9.14806733963546e-6 4.317406997864655e-6 5982/25898/6117/55666/7314/6118/9636/51455/5985/5984/6233/5424/124739/54107/7706/5425/5111/6119/83932/5427/5429/9246/7311/5983/56655/7316/5426/9100/10459/7415/5981 31 Bunyavirus R-HSA-111447 Activation of BAD and translocation to mitochondria 15/4506 15/10654 2.4452801306380117e-6 9.495043181363199e-6 4.481161359474439e-6 7531/10971/7533/2810/637/7534/10000/572/7532/208/7529/5533/596/207/5534 15 Bunyavirus R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 15/4506 15/10654 2.4452801306380117e-6 9.495043181363199e-6 4.481161359474439e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Bunyavirus R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 15/4506 15/10654 2.4452801306380117e-6 9.495043181363199e-6 4.481161359474439e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Bunyavirus R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 15/4506 15/10654 2.4452801306380117e-6 9.495043181363199e-6 4.481161359474439e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Bunyavirus R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 15/4506 15/10654 2.4452801306380117e-6 9.495043181363199e-6 4.481161359474439e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Bunyavirus R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 15/4506 15/10654 2.4452801306380117e-6 9.495043181363199e-6 4.481161359474439e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Bunyavirus R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 15/4506 15/10654 2.4452801306380117e-6 9.495043181363199e-6 4.481161359474439e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Bunyavirus R-HSA-5637810 Constitutive Signaling by EGFRvIII 15/4506 15/10654 2.4452801306380117e-6 9.495043181363199e-6 4.481161359474439e-6 5295/4893/5335/2885/3845/3265/5290/6464/6654/1956/2549/11140/1950/867/3320 15 Bunyavirus R-HSA-5637812 Signaling by EGFRvIII in Cancer 15/4506 15/10654 2.4452801306380117e-6 9.495043181363199e-6 4.481161359474439e-6 5295/4893/5335/2885/3845/3265/5290/6464/6654/1956/2549/11140/1950/867/3320 15 Bunyavirus R-HSA-438064 Post NMDA receptor activation events 55/4506 81/10654 2.6903701444186306e-6 1.041771105922103e-5 4.9166121060281996e-6 5563/4893/51807/817/347688/10381/7278/7846/113457/81027/6196/6197/3845/3265/814/5879/818/79861/5567/5594/6714/10376/6195/5613/2906/801/2891/805/5170/84617/3838/2890/10382/7277/10645/5566/84254/5571/27330/347733/3084/816/5577/5562/10383/84790/5564/7280/5595/815/28964/112714/5576/4137/2066 55 Bunyavirus R-HSA-113510 E2F mediated regulation of DNA replication 20/4506 22/10654 2.7086595369181763e-6 1.0430583962607562e-5 4.922687439877465e-6 5925/5422/1869/84515/4998/5518/5001/5558/5515/23594/7027/5557/983/5519/23649/4999/5000/891/23595/5516 20 Bunyavirus R-HSA-392170 ADP signalling through P2Y purinoceptor 12 20/4506 22/10654 2.7086595369181763e-6 1.0430583962607562e-5 4.922687439877465e-6 2788/2770/2782/2773/2787/10681/2792/2785/2783/2784/2771/2791/2786/54331/59345/51764/94235/55970/2793/2790 20 Bunyavirus R-HSA-392451 G beta:gamma signalling through PI3Kgamma 22/4506 25/10654 2.8515284989996585e-6 1.0831146396745297e-5 5.111731856804206e-6 2788/2782/2787/10681/2792/10000/2785/2783/2784/2791/5170/2786/208/387/54331/59345/207/51764/94235/55970/2793/2790 22 Bunyavirus R-HSA-418592 ADP signalling through P2Y purinoceptor 1 22/4506 25/10654 2.8515284989996585e-6 1.0831146396745297e-5 5.111731856804206e-6 2788/1432/2782/2776/2787/10681/2792/6714/2785/2783/2784/2791/2786/5321/54331/59345/51764/94235/55970/2767/2793/2790 22 Bunyavirus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 22/4506 25/10654 2.8515284989996585e-6 1.0831146396745297e-5 5.111731856804206e-6 2308/2475/84335/7249/2932/10000/2931/253260/5170/572/4303/6199/64223/208/1147/2309/842/207/1027/1026/3164/4193 22 Bunyavirus R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 22/4506 25/10654 2.8515284989996585e-6 1.0831146396745297e-5 5.111731856804206e-6 5982/6117/7314/6118/3978/5985/5984/6233/5424/7515/54107/5425/5111/6119/5427/7311/3980/5983/56655/7316/5426/5981 22 Bunyavirus R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 22/4506 25/10654 2.8515284989996585e-6 1.0831146396745297e-5 5.111731856804206e-6 51400/5520/8900/5518/7465/5515/993/890/983/5519/7514/2305/9133/891/4331/5347/5516/1017/994/9088/995/1022 22 Bunyavirus R-HSA-9609507 Protein localization 98/4506 163/10654 2.952425575305726e-6 1.1183916445587452e-5 5.2782207796512555e-6 6804/6811/9218/26519/7321/131118/10965/5621/26520/3313/10005/8239/10440/50/7917/3417/390916/51142/25813/23203/23417/80273/5192/131474/7314/1891/90639/54332/10952/51608/8528/134266/847/7323/54927/3329/100287932/10469/215/8604/1431/5189/2010/8540/6233/6844/9804/83752/55670/373156/189/3155/5193/30/351/51/8266/7416/293/1678/150274/118424/29090/54363/5830/10651/54469/7311/5195/401505/6449/2395/3295/10063/10452/5824/23480/7316/400916/10165/7322/56993/3416/26521/100272147/4843/26517/5190/92609/617/5828/224/1537/388753/2671/5194/5191/291 98 Bunyavirus R-HSA-5685942 HDR through Homologous Recombination (HRR) 47/4506 67/10654 3.5209036330287966e-6 1.330119150255323e-5 6.277463330888599e-6 5892/9156/7486/5982/472/80198/4683/84126/672/6117/348654/7314/6118/5888/7517/84464/5985/5984/6233/5884/5810/5424/54107/580/11073/5425/641/5111/6119/3364/10524/5427/5429/1111/7311/5983/56655/51750/5883/10111/675/545/7316/5426/10635/5932/5981 47 Bunyavirus R-HSA-76002 Platelet activation, signaling and aggregation 147/4506 262/10654 3.626784676199108e-6 1.3664156320598801e-5 6.4487636490026814e-6 5295/2788/5579/2153/5770/2770/3959/5578/5582/388/5583/29106/3709/1432/3920/374354/2244/3309/2534/3690/408/2768/2782/87/2776/5894/10487/2885/7040/9564/2773/5879/5054/2787/1072/5290/7018/5340/813/7094/5594/10681/7414/83706/7534/2792/6714/6694/3671/7273/22927/1191/226/5588/2335/1/2785/2783/2784/1445/5478/2771/7410/5580/2266/7409/7873/3932/7076/2243/8527/3710/801/5781/2151/2791/2147/805/5170/5590/351/6464/135228/5747/51097/3937/2316/409/6915/2157/7277/334/10257/335/51706/308/6850/8503/197/4067/81/9948/998/2786/6654/8407/7450/387/29789/10916/5595/139322/5321/54331/5005/5919/59345/1606/207/7422/51764/94235/3708/3827/1950/55970/2621/5216/2767/5768/6647/2793/5265/55664/391/2/1398/5906/5296/5581/213/5660/7057/2207/5627/2790/10672 147 Bunyavirus R-HSA-389356 CD28 co-stimulation 27/4506 33/10654 3.7924691198291013e-6 1.4249870493374035e-5 6.7251899557190764e-6 5295/2534/2885/2475/5062/5879/1326/5290/57761/9020/6714/10000/7525/7409/3932/253260/5170/64223/8503/4067/5063/998/208/5058/9402/207/5296 27 Bunyavirus R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 30/4506 38/10654 4.359225509765971e-6 1.6335377313477858e-5 7.709439568771172e-6 3313/6175/5898/3181/4001/4282/5062/1072/6627/9049/27250/9987/3185/3458/5478/302/552900/6775/4478/998/6648/6888/3586/829/6647/6950/5306/4507/375/5721 30 Bunyavirus R-HSA-1433557 Signaling by SCF-KIT 33/4506 43/10654 4.423879756317218e-6 1.653321281583432e-5 7.802807528427435e-6 5295/4893/5578/3717/2534/2885/9846/3845/3265/5879/5290/3815/9306/6714/7525/7409/3932/6777/5781/2241/6774/6772/8503/4067/1111/6654/9402/867/4254/5296/10076/2887/2242 33 Bunyavirus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 40/4506 55/10654 4.4946586103327035e-6 1.675281845669462e-5 7.906449849304644e-6 4790/7295/29108/1432/10628/5603/83737/3654/7334/1540/3551/7314/23118/841/8517/5970/7128/837/598/10454/6233/4791/351/9051/330/64127/3656/7189/3326/7311/114548/1147/596/6885/842/10392/10910/835/7316/329 40 Bunyavirus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 61/4506 93/10654 4.568601535024052e-6 1.6937847180381725e-5 7.993773682502892e-6 8454/3725/9252/4790/4792/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/54106/8945/1326/5606/5594/4214/23118/8517/5528/5970/9261/5519/5598/6195/10454/6233/51311/2353/4791/3665/351/51295/79155/64127/5602/3656/7189/7311/6416/51284/5595/5516/1147/1845/6885/5604/10392/6500/7099/4615/7316/4793/23291/5609/5599 61 Bunyavirus R-HSA-975155 MyD88 dependent cascade initiated on endosome 61/4506 93/10654 4.568601535024052e-6 1.6937847180381725e-5 7.993773682502892e-6 8454/3725/9252/4790/4792/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/54106/8945/1326/5606/5594/4214/23118/8517/5528/5970/9261/5519/5598/6195/10454/6233/51311/2353/4791/3665/351/51295/79155/64127/5602/3656/7189/7311/6416/51284/5595/5516/1147/1845/6885/5604/10392/6500/7099/4615/7316/4793/23291/5609/5599 61 Bunyavirus R-HSA-114452 Activation of BH3-only proteins 25/4506 30/10654 4.657764662207876e-6 1.7222609918084295e-5 8.128166728688882e-6 7531/10971/7533/2810/1869/8655/7159/637/7027/7534/10000/7157/140735/572/7532/8626/208/7161/7529/5533/596/10018/207/5534/5599 25 Bunyavirus R-HSA-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 17/4506 18/10654 4.716429181113359e-6 1.7393392271090008e-5 8.20876702365873e-6 8792/10673/8740/7187/51330/958/9020/8742/959/4055/8600/330/115650/4050/7186/329/4049 17 Bunyavirus R-HSA-1250347 SHC1 events in ERBB4 signaling 14/4506 14/10654 5.7920259550286085e-6 2.091731653189088e-5 9.871874071155934e-6 4893/145957/9542/2885/3845/3265/1839/2069/6464/3084/6654/10718/685/2066 14 Bunyavirus R-HSA-3371568 Attenuation phase 14/4506 14/10654 5.7920259550286085e-6 2.091731653189088e-5 9.871874071155934e-6 3305/1387/3306/3312/3303/3337/3297/3281/3326/3304/10728/3320/2033/2288 14 Bunyavirus R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 14/4506 14/10654 5.7920259550286085e-6 2.091731653189088e-5 9.871874071155934e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Bunyavirus R-HSA-4839744 truncated APC mutants destabilize the destruction complex 14/4506 14/10654 5.7920259550286085e-6 2.091731653189088e-5 9.871874071155934e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Bunyavirus R-HSA-4839748 AMER1 mutants destabilize the destruction complex 14/4506 14/10654 5.7920259550286085e-6 2.091731653189088e-5 9.871874071155934e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Bunyavirus R-HSA-5467337 APC truncation mutants have impaired AXIN binding 14/4506 14/10654 5.7920259550286085e-6 2.091731653189088e-5 9.871874071155934e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Bunyavirus R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 14/4506 14/10654 5.7920259550286085e-6 2.091731653189088e-5 9.871874071155934e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Bunyavirus R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 14/4506 14/10654 5.7920259550286085e-6 2.091731653189088e-5 9.871874071155934e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Bunyavirus R-HSA-6782135 Dual incision in TC-NER 46/4506 66/10654 5.914265013079474e-6 2.130357991791418e-5 1.0054170088874396e-5 2074/5982/5431/5435/9978/5433/5439/6117/7314/6118/5438/5985/5984/6233/7874/5424/8451/10450/5434/5436/54107/8450/4331/5425/5111/6119/5427/1161/1642/7311/5983/5432/56655/6917/5440/27339/5430/5441/7316/5426/5437/2033/56949/9716/5981/1022 46 Bunyavirus R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 21/4506 24/10654 5.973919116405142e-6 2.146299806254837e-5 1.0129407074750987e-5 2237/5982/5422/6117/5558/6118/3978/5557/5985/5984/23649/5424/54107/5425/5111/6119/5427/5983/56655/5426/5981 21 Bunyavirus R-HSA-445355 Smooth Muscle Contraction 31/4506 40/10654 6.065266673212656e-6 2.167944036527806e-5 1.0231556466283159e-5 140465/4636/7169/5062/58498/5829/4638/7094/7414/93408/859/800/302/801/805/29895/10627/301/59/5058/4629/7170/72/2977/7168/7171/10174/10398/4637/103910/493829 31 Bunyavirus R-HSA-5675221 Negative regulation of MAPK pathway 31/4506 40/10654 6.065266673212656e-6 2.167944036527806e-5 1.0231556466283159e-5 4893/5526/1852/5605/5037/5894/5518/4140/3845/3265/7314/5515/8844/5594/5528/5519/80824/6233/1843/369/673/5529/7311/5536/7529/5595/5516/5604/5525/7316/5527 31 Bunyavirus R-HSA-75153 Apoptotic execution phase 38/4506 52/10654 6.457936256544717e-6 2.302394665376812e-5 1.086609277248741e-5 2339/10059/660/836/324/4001/3836/6709/6093/840/5062/2934/22985/63967/841/7082/5339/5317/28988/10134/999/5588/5580/1828/5747/118/1829/8428/1832/3148/4000/3837/1676/51765/1499/329/4137/7431 38 Bunyavirus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 60/4506 92/10654 7.184404886082894e-6 2.554862349795805e-5 1.2057607555858779e-5 8454/3725/9252/4790/4792/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/54106/8945/1326/5606/5594/4214/23118/8517/5528/5970/9261/5519/5598/6195/10454/6233/51311/2353/4791/351/51295/79155/64127/5602/3656/7189/7311/6416/51284/5595/5516/1147/1845/6885/5604/10392/6500/7099/4615/7316/4793/23291/5609/5599 60 Bunyavirus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 26/4506 32/10654 7.403965179857295e-6 2.6129436609420432e-5 1.2331720819216017e-5 4738/4089/23327/4088/5499/9110/7040/7314/11171/7046/2280/9958/9040/6233/7514/5500/5501/4087/7048/7311/57154/51377/10273/64750/7316/867 26 Bunyavirus R-HSA-2871796 FCERI mediated MAPK activation 26/4506 32/10654 7.403965179857295e-6 2.6129436609420432e-5 1.2331720819216017e-5 3725/4893/5335/2885/3845/3265/5062/5879/5594/4214/7410/7409/2353/6464/3937/6850/4067/5602/6654/5058/6416/5595/9402/5609/5599/2207 26 Bunyavirus R-HSA-5656169 Termination of translesion DNA synthesis 26/4506 32/10654 7.403965179857295e-6 2.6129436609420432e-5 1.2331720819216017e-5 5982/6117/7314/6118/9636/51455/5985/5984/6233/5424/124739/54107/7706/5425/5111/6119/5427/5429/9246/7311/5983/56655/7316/5426/9100/5981 26 Bunyavirus R-HSA-9020591 Interleukin-12 signaling 35/4506 47/10654 7.4284804575769775e-6 2.6149751913793703e-5 1.2341308575187696e-5 3313/6175/5898/3717/3181/4001/3594/4282/5062/1072/6627/9049/27250/9987/3185/3458/5478/302/552900/7297/6775/4478/998/6648/3716/6888/3586/829/6647/6950/5306/4507/375/5721/5034 35 Bunyavirus R-HSA-400253 Circadian Clock 48/4506 70/10654 7.602976042824063e-6 2.6696595979084995e-5 1.2599390234031659e-5 8454/79718/5936/3091/1387/150094/2155/5499/10499/23054/1386/23411/7314/5054/8945/10135/1454/5465/64784/6604/56938/6233/1453/5500/26224/1374/1407/406/4209/5501/2908/7311/23373/6095/8841/8204/4862/6500/200186/1408/6720/7316/9611/2033/6256/10498/8648/10891 48 Bunyavirus R-HSA-5619115 Disorders of transmembrane transporters 103/4506 176/10654 9.114665816715622e-6 3.172271163278739e-5 1.4971452669706352e-5 23165/5689/5682/6559/348995/143471/91319/57122/5705/23511/5709/5695/554/23279/5711/23225/5683/5699/6400/5702/51009/9972/8021/55746/5696/5691/7314/5718/5700/122706/5707/10956/79139/91445/23198/10762/9861/79902/9883/5698/215/5692/6521/5713/5710/8647/5719/10613/6233/6575/27248/6396/129401/4928/5903/55706/7175/6048/5706/19/335/5714/4927/5688/5687/5708/8086/5704/7311/11160/5694/9197/81929/5684/5720/9631/5690/5717/9491/1080/79023/23636/10197/1244/7316/10213/53371/3098/9688/7415/5715/5701/5685/682/5686/6520/5716/213/5693/5721/6566/8480/1356 103 Bunyavirus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 56/4506 85/10654 9.125399831239415e-6 3.172271163278739e-5 1.4971452669706352e-5 8454/3725/9252/4790/4792/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/8945/1326/5606/5594/4214/23118/8517/5528/5970/9261/5519/5598/6195/10454/6233/2353/4791/351/51295/79155/64127/5602/3656/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/4615/7316/4793/23291/5609/5599 56 Bunyavirus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 56/4506 85/10654 9.125399831239415e-6 3.172271163278739e-5 1.4971452669706352e-5 8454/3725/9252/4790/4792/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/8945/1326/5606/5594/4214/23118/8517/5528/5970/9261/5519/5598/6195/10454/6233/2353/4791/351/51295/79155/64127/5602/3656/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/4615/7316/4793/23291/5609/5599 56 Bunyavirus R-HSA-975871 MyD88 cascade initiated on plasma membrane 56/4506 85/10654 9.125399831239415e-6 3.172271163278739e-5 1.4971452669706352e-5 8454/3725/9252/4790/4792/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/8945/1326/5606/5594/4214/23118/8517/5528/5970/9261/5519/5598/6195/10454/6233/2353/4791/351/51295/79155/64127/5602/3656/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/4615/7316/4793/23291/5609/5599 56 Bunyavirus R-HSA-5620922 BBSome-mediated cargo-targeting to cilium 20/4506 23/10654 1.244786823146155e-5 4.316499580760547e-5 2.037160943876269e-5 79738/123016/10576/54585/166379/10575/117177/582/6753/585/583/22948/10694/7203/6950/55212/92482/8195/129880/27241 20 Bunyavirus R-HSA-2028269 Signaling by Hippo 18/4506 20/10654 1.2601112825377401e-5 4.358796843319131e-5 2.0571230288261398e-5 154810/7531/60485/10413/26524/836/9113/23286/1856/7082/55233/154796/51421/261734/6788/7529/25937/92597 18 Bunyavirus R-HSA-209560 NF-kB is activated and signals survival 13/4506 13/10654 1.3717549118063499e-5 4.709917110980423e-5 2.2228333416618324e-5 4790/8878/4792/3654/3551/7314/5970/6233/7189/7311/4804/7316/4803 13 Bunyavirus R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13/4506 13/10654 1.3717549118063499e-5 4.709917110980423e-5 2.2228333416618324e-5 7531/10971/7533/2810/11200/7465/7534/983/7532/891/1111/7529/995 13 Bunyavirus R-HSA-8847993 ERBB2 Activates PTK6 Signaling 13/4506 13/10654 1.3717549118063499e-5 4.709917110980423e-5 2.2228333416618324e-5 2064/5753/145957/9542/1839/2065/2069/3084/10718/1956/685/1950/2066 13 Bunyavirus R-HSA-2219528 PI3K/AKT Signaling in Cancer 64/4506 101/10654 1.469177888910205e-5 5.032024513859523e-5 2.3748511071224058e-5 5295/2308/374/7039/2064/145957/2534/9542/2885/2475/8660/5879/1839/5290/3667/6801/2065/3815/2069/84335/8074/7249/2260/6714/2099/2932/10000/7409/3932/2931/5781/253260/5170/572/4303/6199/4233/64223/8503/5159/3084/208/10718/1956/2549/1147/685/2309/842/207/1027/2100/1950/1026/50852/2261/2255/3164/391/5728/2066/4254/5296/4193 64 Bunyavirus R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF) 39/4506 55/10654 1.5934144388680327e-5 5.444165999465778e-5 2.5693602277928806e-5 79718/51141/10484/3638/1387/4801/9632/10499/23054/31/8720/5465/2222/3157/6667/3156/6604/51128/6319/6721/10802/4800/57678/32/1595/5901/4047/9871/3837/4802/79071/6720/2194/6256/10498/3422/4520/8648/10427 39 Bunyavirus R-HSA-6806834 Signaling by MET 52/4506 79/10654 1.967547761980098e-5 6.689662390732332e-5 3.1571690660784626e-5 5295/4893/5770/3688/3910/3908/6456/30011/2885/3845/3265/1399/7314/5879/3918/5290/3911/2060/284217/9101/6714/9146/2335/64759/3909/84951/6233/5781/6464/85440/5747/382/3912/6774/4233/5771/3913/6654/7311/2549/53916/26018/10048/7316/3915/3673/867/3914/1398/5906/10319/10254 52 Bunyavirus R-HSA-8852135 Protein ubiquitination 52/4506 79/10654 1.967547761980098e-5 6.689662390732332e-5 3.1571690660784626e-5 11065/7321/56852/65264/8239/56254/7347/7328/5192/7334/7332/80349/7314/90268/79139/7323/29089/7324/6233/23168/7874/5193/123169/9646/79577/5591/7317/51255/8915/5111/92305/9810/8078/118424/5830/7311/5195/9781/3105/997/7319/51322/7320/7336/7316/54926/7415/7322/54623/5828/27338/5194 52 Bunyavirus R-HSA-9006936 Signaling by TGF-beta family members 64/4506 102/10654 2.3251374450673212e-5 7.8862325995714e-5 3.7218873176260106e-5 10272/892/7321/4738/91851/130399/8239/4609/4089/22938/23327/4088/5499/9110/7040/904/7314/5054/7027/11167/6497/51592/7323/91/93/6667/11171/7046/94/2280/9958/9040/6233/7514/1025/8928/57530/5500/4090/4221/4093/5590/269/5501/1874/142/4087/7048/7311/387/57154/51377/10273/50855/4086/64750/54778/7316/9611/867/3065/657/56288/25937 64 Bunyavirus R-HSA-110312 Translesion synthesis by REV1 15/4506 16/10654 2.3641232160663127e-5 7.979631387884843e-5 3.765966637036946e-5 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/7311/5983/7316/10459/5981 15 Bunyavirus R-HSA-193639 p75NTR signals via NF-kB 15/4506 16/10654 2.3641232160663127e-5 7.979631387884843e-5 3.765966637036946e-5 4790/8878/4792/3654/3551/7314/5970/6233/7189/7311/4804/5584/4615/7316/4803 15 Bunyavirus R-HSA-448424 Interleukin-17 signaling 48/4506 72/10654 2.4606483090026713e-5 8.285371359298849e-5 3.910259835053826e-5 8454/3725/9252/4790/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/8945/1326/5606/5594/23118/8517/5528/9261/5519/5598/6195/10454/6233/2353/79155/64127/5602/3656/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/7316/23291/5609/5599 48 Bunyavirus R-HSA-190236 Signaling by FGFR 56/4506 87/10654 2.5578387092574525e-5 8.591872676397323e-5 4.054912348220439e-5 5295/4893/5335/54845/5431/5435/5433/5439/7072/2885/7073/5518/3845/3265/7314/5515/5290/5594/8074/2260/5438/3185/6714/4670/6233/200734/5781/5725/2963/5434/6464/5436/673/2962/80004/6654/7311/2549/5432/22916/5595/5516/5440/23543/5430/3178/10817/5441/4686/7316/2261/867/5437/2255/3187/161742 56 Bunyavirus R-HSA-912631 Regulation of signaling by CBL 19/4506 22/10654 2.5785830662477626e-5 8.640732678724474e-5 4.077971701429281e-5 5295/2534/2885/1399/7314/5290/6233/7525/7409/6850/8503/4067/29760/7311/7316/3055/867/1398/5296 19 Bunyavirus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 24/4506 30/10654 2.7654901123429076e-5 9.244827857568377e-5 4.363072876976694e-5 7124/10616/1540/3551/7314/81858/8737/55072/23118/8517/7128/10454/6233/331/8717/330/7311/1147/7186/6885/7316/329/9099/7185 24 Bunyavirus R-HSA-442755 Activation of NMDA receptors and postsynaptic events 59/4506 93/10654 2.982898678656183e-5 9.947753009681147e-5 4.69481660579228e-5 5563/4893/51807/817/347688/10381/7278/7846/113457/81027/6196/6197/3845/3265/814/5879/818/79861/5567/5594/2892/6714/22843/10376/6195/5613/2906/801/2891/805/5170/84617/3838/8573/2890/10382/7277/10645/5566/84254/5571/27330/347733/3084/816/5577/2893/5562/10383/84790/5564/7280/5595/815/28964/112714/5576/4137/2066 59 Bunyavirus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 60/4506 95/10654 3.118564685118997e-5 1.0350664692990195e-4 4.8849697448605846e-5 8454/3725/9252/4790/4792/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/8945/1326/5606/11213/5594/4214/23118/8517/5528/5970/9261/5519/5598/6195/10454/6233/2353/4791/351/51295/79155/64127/5602/3656/695/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/7099/4615/7316/4793/23291/5609/5599/7097 60 Bunyavirus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 60/4506 95/10654 3.118564685118997e-5 1.0350664692990195e-4 4.8849697448605846e-5 8454/3725/9252/4790/4792/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/8945/1326/5606/11213/5594/4214/23118/8517/5528/5970/9261/5519/5598/6195/10454/6233/2353/4791/351/51295/79155/64127/5602/3656/695/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/7099/4615/7316/4793/23291/5609/5599/7097 60 Bunyavirus R-HSA-176974 Unwinding of DNA 12/4506 12/10654 3.248379121371426e-5 1.0730427713724568e-4 5.0641979317963114e-5 4174/84515/84296/64785/4175/4172/8318/4173/51659/4176/9837/4171 12 Bunyavirus R-HSA-3371511 HSF1 activation 12/4506 12/10654 3.248379121371426e-5 1.0730427713724568e-4 5.0641979317963114e-5 7531/1915/6117/6118/10013/3297/6119/3281/3326/10728/7415/3320 12 Bunyavirus R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 31/4506 42/10654 3.3577522193357613e-5 1.1065500221640783e-4 5.22233454543947e-5 56998/9070/5929/6657/324/6932/25776/6659/7314/51176/8945/7534/7091/83439/6233/7514/7089/331/4221/7090/6934/607/7088/208/57680/7311/1487/1499/207/7316/3065 31 Bunyavirus R-HSA-5693532 DNA Double-Strand Break Repair 96/4506 166/10654 3.513217966029496e-5 1.1550532652464898e-4 5.4512443613913476e-5 2237/151987/5892/9156/7486/5982/11200/472/6613/80198/3981/2140/4683/165918/84126/8900/8924/672/6117/7334/348654/55183/7314/6118/25/5888/322/51588/7518/51720/63967/5531/890/7517/9656/84464/5985/7157/5984/6233/7158/6047/5884/5810/5424/8467/3838/7515/54107/580/11073/5591/5425/641/5111/6119/3364/22976/10524/5427/55775/5429/142/1111/7329/7311/23030/3980/5536/5983/10038/2547/56655/51750/1017/54962/5893/5883/10111/7520/675/51548/545/7336/29086/7316/8314/5426/10635/7341/8914/5932/9025/79184/5599/5981 96 Bunyavirus R-HSA-397795 G-protein beta:gamma signalling 25/4506 32/10654 3.920152598867235e-5 1.285810052428453e-4 6.06834767626507e-5 2788/2782/2787/10681/2792/10000/2785/2783/2784/2791/5170/998/695/2786/208/387/5058/54331/59345/207/51764/94235/55970/2793/2790 25 Bunyavirus R-HSA-69231 Cyclin D associated events in G1 32/4506 44/10654 4.1105170879414934e-5 1.3419346184052557e-4 6.33322613081088e-5 8454/5925/1869/5753/3717/5520/5518/7314/5515/25/7027/6714/5519/6502/595/6233/1163/1019/1029/4331/4067/1874/7311/5516/894/1027/6500/7316/1026/1871/1021/1022 32 Bunyavirus R-HSA-69236 G1 Phase 32/4506 44/10654 4.1105170879414934e-5 1.3419346184052557e-4 6.33322613081088e-5 8454/5925/1869/5753/3717/5520/5518/7314/5515/25/7027/6714/5519/6502/595/6233/1163/1019/1029/4331/4067/1874/7311/5516/894/1027/6500/7316/1026/1871/1021/1022 32 Bunyavirus R-HSA-1980143 Signaling by NOTCH1 48/4506 73/10654 4.2497189116500193e-5 1.384137421224329e-4 6.532401179983429e-5 8454/79718/892/113878/3091/23385/9978/9759/4609/22938/1387/408/83737/57534/7314/79885/2648/9734/55869/51564/3280/10013/83933/7091/8650/1272/102/8850/3066/6233/7089/5663/7090/23220/409/10014/7088/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 48 Bunyavirus R-HSA-4086398 Ca2+ pathway 42/4506 62/10654 4.417295985379067e-5 1.4353637770672306e-4 6.774162657003845e-5 2788/5578/27327/2775/5530/3709/2782/192669/6932/4343/5593/3845/2787/51176/10681/83439/2792/2785/2783/2784/3710/26523/801/2791/805/4772/6934/2786/27161/815/54331/6885/1499/59345/51764/94235/3708/192670/55970/2793/5534/2790 42 Bunyavirus R-HSA-381119 Unfolded Protein Response (UPR) 59/4506 94/10654 4.7286409370431746e-5 1.5329594107530665e-4 7.234762755574014e-5 5393/10525/1965/2673/5526/811/9570/55738/10130/3309/4801/6745/6347/9820/8720/9695/7094/58477/468/3484/22872/51726/3068/8894/7466/9451/2931/8570/23016/1968/1200/6464/37/7184/7494/118/1051/84447/5611/4800/1639/11015/4189/22926/56915/167227/22894/4000/10113/440/9709/4802/1649/2081/30827/467/10106/54512/7709 59 Bunyavirus R-HSA-9006931 Signaling by Nuclear Receptors 160/4506 299/10654 4.86699464338106e-5 1.574150935701438e-4 7.42916510468473e-5 5295/2788/374/3725/4893/857/7764/79718/7031/5160/5165/2770/7039/27327/5431/5435/5433/1509/4609/1387/8312/2782/5439/192669/10499/1386/5914/4343/3845/904/7392/3265/8877/2773/10062/2787/1839/5290/6801/5594/2069/10681/1737/5481/5438/348/4313/1655/6667/2792/6714/2099/8850/5467/10000/5162/2785/595/2783/2784/2771/7514/1025/2353/26523/801/2791/2957/805/5105/5170/2963/3838/5434/5590/6464/1374/7090/5241/6319/5747/5436/3315/200845/5885/19/57678/2962/8503/10524/2171/8243/4602/2786/208/3326/23030/6908/1956/5536/3169/858/23189/5432/3480/10728/5595/7528/27161/596/5440/8841/685/54331/4435/347/2309/59345/8204/5430/207/2625/1027/51764/94235/5441/10735/6720/192670/2100/1950/9611/55970/2194/4314/127/2289/7391/220/2958/5163/5437/2793/3320/2033/4846/9126/3065/2066/861/23028/6256/10498/1738/5296/3276/8202/8648/2288/2790 160 Bunyavirus R-HSA-6785631 ERBB2 Regulates Cell Motility 14/4506 15/10654 5.264646749649667e-5 1.689175067402375e-4 7.972018554153021e-5 2064/145957/9542/1839/2065/2069/1729/3084/10718/387/1956/685/1950/2066 14 Bunyavirus R-HSA-5218920 VEGFR2 mediated vascular permeability 23/4506 29/10654 5.2860952811106305e-5 1.689175067402375e-4 7.972018554153021e-5 857/2475/5062/5879/57761/1500/10000/3728/7410/7409/801/253260/805/5170/64223/5063/208/5058/1495/1499/207/3320/4846 23 Bunyavirus R-HSA-389513 CTLA4 inhibitory signaling 18/4506 21/10654 5.307451072612915e-5 1.689175067402375e-4 7.972018554153021e-5 5526/2534/5518/5515/5528/6714/5519/10000/7525/3932/5781/4067/5529/208/5516/5525/207/5527 18 Bunyavirus R-HSA-445144 Signal transduction by L1 18/4506 21/10654 5.307451072612915e-5 1.689175067402375e-4 7.972018554153021e-5 1459/1460/8829/4684/3688/1457/5605/3690/5879/5594/2260/7410/3685/3897/1956/5058/5595/5604 18 Bunyavirus R-HSA-5621575 CD209 (DC-SIGN) signaling 18/4506 21/10654 5.307451072612915e-5 1.689175067402375e-4 7.972018554153021e-5 9252/4893/4790/1387/2534/5894/3845/3265/5062/5567/5970/3384/5566/4067/5063/5971/5058/2033 18 Bunyavirus R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 18/4506 21/10654 5.307451072612915e-5 1.689175067402375e-4 7.972018554153021e-5 2237/5982/6117/6118/328/3978/5985/5984/5424/54107/5425/5111/6119/5427/5983/56655/5426/5981 18 Bunyavirus R-HSA-901032 ER Quality Control Compartment (ERQC) 18/4506 21/10654 5.307451072612915e-5 1.689175067402375e-4 7.972018554153021e-5 6400/51009/7314/9695/10956/91445/11253/80267/6233/267/6048/56886/10206/84447/7311/7844/7316/11236 18 Bunyavirus R-HSA-168638 NOD1/2 Signaling Pathway 27/4506 36/10654 6.830821864403433e-5 2.1690582412251446e-4 1.0236814926872427e-4 1432/5603/83737/3654/7334/1540/3551/7314/23118/841/8517/7128/837/10454/6233/330/64127/3656/7189/7311/1147/6885/842/10392/835/7316/329 27 Bunyavirus R-HSA-110373 Resolution of AP sites via the multiple-nucleotide patch replacement pathway 21/4506 26/10654 6.974431902281919e-5 2.2046163428074818e-4 1.0404630478401241e-4 2237/5982/8505/6117/6118/328/3978/5985/5984/5424/54107/5425/5111/6119/5427/142/5983/10038/56655/5426/5981 21 Bunyavirus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 21/4506 26/10654 6.974431902281919e-5 2.2046163428074818e-4 1.0404630478401241e-4 23327/4088/5499/9110/7040/7314/11171/7046/9958/6233/7514/5500/5501/4087/7048/7311/57154/51377/10273/64750/7316 21 Bunyavirus R-HSA-8943724 Regulation of PTEN gene transcription 41/4506 61/10654 7.178668499151606e-5 2.2640416035785832e-4 1.0685086477660763e-4 1912/3725/9112/6045/80012/1911/5928/23512/1107/2475/1386/23186/2146/51564/5594/7101/84733/3066/7157/8726/57521/28956/9219/8535/5931/1108/2122/64223/10014/54815/648/23466/53615/5595/8841/5468/5978/8649/6615/3065/23028 41 Bunyavirus R-HSA-2514853 Condensation of Prometaphase Chromosomes 11/4506 11/10654 7.691323468021383e-5 2.4093718908813053e-4 1.1370969053845926e-4 1459/1460/1457/64151/10051/983/23397/9133/891/10592/9918 11 Bunyavirus R-HSA-5625970 RHO GTPases activate KTN1 11/4506 11/10654 7.691323468021383e-5 2.4093718908813053e-4 1.1370969053845926e-4 64837/3798/5879/89953/147700/3831/3895/998/387/391/3799 11 Bunyavirus R-HSA-9614399 Regulation of localization of FOXO transcription factors 11/4506 11/10654 7.691323468021383e-5 2.4093718908813053e-4 1.1370969053845926e-4 2308/10971/2810/7534/10000/7532/4303/208/7529/2309/207 11 Bunyavirus R-HSA-1226099 Signaling by FGFR in disease 42/4506 63/10654 7.853990134546665e-5 2.454812163129608e-4 1.1585423257237825e-4 5295/4893/11052/5335/9530/613/5431/5435/5433/11064/5439/2885/9846/3845/3265/7750/8805/26127/5290/8074/2260/5438/399687/6777/2963/5434/5436/6774/6772/2962/6654/11160/2549/5432/22916/5440/5430/5441/4686/2261/5437/2255 42 Bunyavirus R-HSA-3899300 SUMOylation of transcription cofactors 32/4506 45/10654 8.466296132226133e-5 2.6402722166271207e-4 1.246069723923545e-4 1912/6045/80012/6613/59348/1911/1387/4152/10499/11315/51588/1655/84733/10155/7690/7703/8554/8535/4869/10210/10521/1616/7329/25942/648/1487/8204/7341/2033/6294/8648/10891 32 Bunyavirus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 43/4506 65/10654 8.528777377092416e-5 2.653521548487088e-4 1.252322712228672e-4 3725/4436/5892/472/5431/5435/5433/5439/672/1386/11198/904/51497/2176/5438/1643/9656/2177/7157/1025/2353/6829/2963/5434/5436/4292/4331/2962/1111/55215/5432/6917/5440/8621/5430/6749/545/5441/5395/9150/5437/1022/8178 43 Bunyavirus R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 28/4506 38/10654 8.546852046418239e-5 2.653521548487088e-4 1.252322712228672e-4 1912/1459/6045/80012/1460/1457/1911/10138/196528/86/51412/84733/6604/8289/6602/23429/55193/6595/6597/8535/6599/648/6601/23466/6598/2033/84333/861 28 Bunyavirus R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 19/4506 23/10654 8.914115220980396e-5 2.7613948040103715e-4 1.3032332194415783e-4 5431/5435/5433/5439/51497/5438/6829/2963/5434/5436/2962/5432/22916/5440/5430/5441/4686/9150/5437 19 Bunyavirus R-HSA-8878171 Transcriptional regulation by RUNX1 130/4506 239/10654 9.296624106389976e-5 2.873501996520538e-4 1.3561419223932165e-4 1912/9070/5689/5579/5682/1459/6045/5929/27327/80012/1460/143471/8013/5705/5709/5695/1457/1911/10413/5711/1387/3558/5683/10138/5699/8312/5702/192669/83737/6688/4343/4778/5696/5691/7314/55170/5718/25/4773/196528/5700/122706/5707/23198/86/7082/51412/6714/2099/9861/8850/84733/5588/6604/8289/5698/5692/5713/6602/595/5710/3458/5719/6233/26523/5781/23429/55193/6595/6597/6929/8535/3958/5706/6599/200845/4331/57678/2623/5714/5688/5687/5708/4602/5704/7311/7161/58508/25942/648/5694/6601/23466/4297/4004/27161/894/5684/5720/11091/640/5690/2625/5717/9491/4005/6598/10197/192670/7316/10213/10398/5715/5701/5685/5686/2033/1021/84333/50943/3065/861/9757/5716/9739/3276/7057/1022/5693/5721 130 Bunyavirus R-HSA-202433 Generation of second messenger molecules 25/4506 33/10654 9.664975281946408e-5 2.9807468015560383e-4 1.4067558340047752e-4 5335/3115/3113/3117/3127/5062/3126/3702/3932/3120/3937/3123/3122/920/5063/7535/3125/5058/55740/9402/4690/3119/915/917/7408 25 Bunyavirus R-HSA-4551638 SUMOylation of chromatin organization proteins 46/4506 71/10654 1.0511412321587341e-4 3.2346376989608733e-4 1.5265789940727522e-4 1912/23165/6045/80012/348995/6613/57122/23511/9759/1911/23279/23225/23512/1107/9972/8021/55746/83746/10762/79902/9883/84733/3066/6396/129401/7703/8554/4928/5903/55706/7175/8535/4927/8086/7329/648/23468/81929/9631/79023/23636/53371/9688/7341/3065/8480 46 Bunyavirus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 17/4506 20/10654 1.0847861633987848e-4 3.2945357555074205e-4 1.5548477287564283e-4 7321/7334/3551/7314/11035/8737/8517/7323/6233/330/7098/7189/7311/1147/7316/7322/329 17 Bunyavirus R-HSA-418217 G beta:gamma signalling through PLC beta 17/4506 20/10654 1.0847861633987848e-4 3.2945357555074205e-4 1.5548477287564283e-4 2788/2782/2787/10681/2792/2785/2783/2784/2791/2786/54331/59345/51764/94235/55970/2793/2790 17 Bunyavirus R-HSA-5213460 RIPK1-mediated regulated necrosis 17/4506 20/10654 1.0847861633987848e-4 3.2945357555074205e-4 1.5548477287564283e-4 356/7314/11035/8737/841/6233/8772/331/8717/330/8837/197259/7311/7186/355/7316/329 17 Bunyavirus R-HSA-5218859 Regulated Necrosis 17/4506 20/10654 1.0847861633987848e-4 3.2945357555074205e-4 1.5548477287564283e-4 356/7314/11035/8737/841/6233/8772/331/8717/330/8837/197259/7311/7186/355/7316/329 17 Bunyavirus R-HSA-69186 Lagging Strand Synthesis 17/4506 20/10654 1.0847861633987848e-4 3.2945357555074205e-4 1.5548477287564283e-4 2237/5982/5422/6117/5558/6118/3978/5557/5985/5984/23649/5424/5425/5111/6119/5983/5981 17 Bunyavirus R-HSA-8876384 Listeria monocytogenes entry into host cells 17/4506 20/10654 1.0847861633987848e-4 3.2945357555074205e-4 1.5548477287564283e-4 6456/30011/2885/7314/2060/1500/6714/999/9146/6233/4233/7311/79872/1499/7316/867/10254 17 Bunyavirus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 60/4506 98/10654 1.1567091329268534e-4 3.4849806045203144e-4 1.644727688458202e-4 8454/3725/9252/4790/4792/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/8945/1326/5606/11213/5594/4214/23118/8517/5528/5970/9261/5519/5598/6195/10454/6233/2353/4791/351/51295/79155/64127/5602/3656/695/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/7099/4615/7316/4793/23291/5609/5599/7097 60 Bunyavirus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 60/4506 98/10654 1.1567091329268534e-4 3.4849806045203144e-4 1.644727688458202e-4 8454/3725/9252/4790/4792/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/8945/1326/5606/11213/5594/4214/23118/8517/5528/5970/9261/5519/5598/6195/10454/6233/2353/4791/351/51295/79155/64127/5602/3656/695/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/7099/4615/7316/4793/23291/5609/5599/7097 60 Bunyavirus R-HSA-162594 Early Phase of HIV Life Cycle 13/4506 14/10654 1.16749350237517e-4 3.4849806045203144e-4 1.644727688458202e-4 2237/7852/3981/3836/7518/3978/11168/5478/920/2547/3159/7520/8815 13 Bunyavirus R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 13/4506 14/10654 1.16749350237517e-4 3.4849806045203144e-4 1.644727688458202e-4 5861/2801/5594/983/8615/9133/891/81876/5347/5595/5862/26003/64689 13 Bunyavirus R-HSA-177504 Retrograde neurotrophin signalling 13/4506 14/10654 1.16749350237517e-4 3.4849806045203144e-4 1.644727688458202e-4 1785/6456/163/1759/161/4914/1213/1211/1175/1173/160/26052/4803 13 Bunyavirus R-HSA-180336 SHC1 events in EGFR signaling 13/4506 14/10654 1.16749350237517e-4 3.4849806045203144e-4 1.644727688458202e-4 374/4893/7039/2885/3845/3265/1839/2069/6464/6654/1956/685/1950 13 Bunyavirus R-HSA-198323 AKT phosphorylates targets in the cytosol 13/4506 14/10654 1.16749350237517e-4 3.4849806045203144e-4 1.644727688458202e-4 84335/7249/2932/10000/2931/572/208/1147/842/207/1027/1026/4193 13 Bunyavirus R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 13/4506 14/10654 1.16749350237517e-4 3.4849806045203144e-4 1.644727688458202e-4 4893/5753/9564/3845/3265/5829/5879/5921/1793/387/63916/1398/9844 13 Bunyavirus R-HSA-180292 GAB1 signalosome 15/4506 17/10654 1.2162319653634614e-4 3.592007118043782e-4 1.6952385779486252e-4 5295/374/7039/2885/5829/1839/5290/2069/6714/1445/5781/1956/2549/685/1950 15 Bunyavirus R-HSA-196299 Beta-catenin phosphorylation cascade 15/4506 17/10654 1.2162319653634614e-4 3.592007118043782e-4 1.6952385779486252e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Bunyavirus R-HSA-5655862 Translesion synthesis by POLK 15/4506 17/10654 1.2162319653634614e-4 3.592007118043782e-4 1.6952385779486252e-4 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/7311/5983/7316/10459/5981 15 Bunyavirus R-HSA-5656121 Translesion synthesis by POLI 15/4506 17/10654 1.2162319653634614e-4 3.592007118043782e-4 1.6952385779486252e-4 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/7311/5983/7316/10459/5981 15 Bunyavirus R-HSA-9034015 Signaling by NTRK3 (TRKC) 15/4506 17/10654 1.2162319653634614e-4 3.592007118043782e-4 1.6952385779486252e-4 5295/4893/5335/2885/3845/3265/5290/3667/6714/5800/6464/5802/6654/4916/581 15 Bunyavirus R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 30/4506 42/10654 1.2376582754227255e-4 3.6475594840153897e-4 1.7214563750733358e-4 5892/9156/7486/5982/472/4683/84126/672/6117/6118/5888/7517/5985/5984/5884/5810/580/11073/641/6119/3364/10524/1111/5983/5883/10111/675/545/10635/5932 30 Bunyavirus R-HSA-1268020 Mitochondrial protein import 42/4506 64/10654 1.354736348873618e-4 3.973510224312976e-4 1.875287993804735e-4 26519/131118/26520/3313/10440/50/51142/25813/23203/80273/131474/90639/134266/54927/3329/100287932/10469/8604/1431/9804/7416/293/1678/150274/29090/10651/401505/2395/10063/10452/400916/10165/56993/26521/100272147/26517/92609/617/1537/388753/2671/291 42 Bunyavirus R-HSA-4090294 SUMOylation of intracellular receptors 23/4506 30/10654 1.3568083692776017e-4 3.973510224312976e-4 1.875287993804735e-4 7068/6613/7181/4929/9759/8856/7067/5914/10062/51588/2516/5465/2099/8554/5241/2908/7329/367/6095/5468/4306/7341/6256 23 Bunyavirus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 23/4506 30/10654 1.3568083692776017e-4 3.973510224312976e-4 1.875287993804735e-4 11065/7321/65264/8239/7347/7328/7332/7314/90268/29089/7324/6233/7874/7317/8078/7311/997/7319/7320/7316/54926/7322/27338 23 Bunyavirus R-HSA-5685938 HDR through Single Strand Annealing (SSA) 27/4506 37/10654 1.5090951428760845e-4 4.410227734107467e-4 2.081395706272874e-4 9156/7486/5982/472/4683/84126/672/6117/6118/25/5888/5985/5984/5884/5810/580/11073/641/6119/3364/10524/5983/5893/5883/10111/545/5932 27 Bunyavirus R-HSA-157118 Signaling by NOTCH 127/4506 235/10654 1.62010093362153e-4 4.724729500979943e-4 2.2298240112606394e-4 8454/5689/3725/79718/5682/892/4904/113878/27327/3091/23385/5705/5709/9978/1869/5695/9759/4609/11060/22938/5711/1387/4088/5683/408/5699/6400/5702/192669/83737/57534/4343/5696/5691/7314/5718/23286/79885/23509/2648/9734/7027/55869/5700/5707/51564/3280/10013/7534/83933/7091/8650/1272/102/9861/5870/8850/5087/5698/5692/5713/595/5710/3002/3066/7157/5719/6233/2324/7089/26523/5663/10959/1999/4192/7090/23220/171558/409/5706/5714/6772/10014/5688/5687/5708/59/4855/7088/5704/7311/1956/5694/4851/27161/5684/8841/5720/5584/23462/207/5690/5717/9491/6500/51548/10197/192670/488/7316/10213/1950/9611/1871/5715/5701/5685/5686/2033/55294/3065/861/2683/5716/3516/5693/5721 127 Bunyavirus R-HSA-447115 Interleukin-12 family signaling 38/4506 57/10654 1.7091729205659714e-4 4.97408570202289e-4 2.3475070329716125e-4 3313/6175/5898/3717/3181/4001/3594/4282/5062/1072/6627/9049/27250/9987/3185/3458/5478/302/552900/7297/6775/821/4478/6774/6772/998/6648/3716/6888/3586/829/6647/6950/5306/4507/375/5721/5034 38 Bunyavirus R-HSA-381042 PERK regulates gene expression 24/4506 32/10654 1.7534946561309668e-4 5.092440730513683e-4 2.4033643861444176e-4 5393/1965/3309/4801/6347/468/3484/8894/9451/8570/23016/1968/1051/4800/22926/56915/167227/22894/440/9709/4802/1649/467/54512 24 Bunyavirus R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 28/4506 39/10654 1.8084931815150575e-4 5.233601786197378e-4 2.4699849855571706e-4 5892/9156/7486/5982/472/4683/84126/672/6117/6118/5888/5985/5984/5884/5810/580/11073/641/6119/3364/10524/1111/5983/5883/10111/675/545/5932 28 Bunyavirus R-HSA-1250342 PI3K events in ERBB4 signaling 10/4506 10/10654 1.8208729313527462e-4 5.233601786197378e-4 2.4699849855571706e-4 5295/145957/9542/1839/5290/2069/3084/10718/685/2066 10 Bunyavirus R-HSA-381183 ATF6 (ATF6-alpha) activates chaperone genes 10/4506 10/10654 1.8208729313527462e-4 5.233601786197378e-4 2.4699849855571706e-4 811/3309/4801/468/7184/7494/4800/22926/4802/1649 10 Bunyavirus R-HSA-390450 Folding of actin by CCT/TriC 10/4506 10/10654 1.8208729313527462e-4 5.233601786197378e-4 2.4699849855571706e-4 10576/10574/10693/10575/60/22948/10694/7203/908/6950 10 Bunyavirus R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 10/4506 10/10654 1.8208729313527462e-4 5.233601786197378e-4 2.4699849855571706e-4 2308/7295/1387/10628/23411/8850/4303/23410/2309/2033 10 Bunyavirus R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 39/4506 59/10654 1.854133007901088e-4 5.318233360111351e-4 2.509926640541867e-4 7321/56852/56254/5192/7334/7332/80349/7314/79139/7323/7324/6233/23168/5193/123169/9646/79577/5591/51255/8915/5111/92305/9810/118424/5830/7311/5195/9781/3105/7319/51322/7320/7336/7316/7415/7322/54623/5828/5194 39 Bunyavirus R-HSA-202430 Translocation of ZAP-70 to Immunological synapse 16/4506 19/10654 2.2001362084591745e-4 6.271962933726154e-4 2.9600368750123436e-4 3115/3113/3117/26191/3127/3126/3932/3120/3123/3122/920/7535/3125/3119/915/917 16 Bunyavirus R-HSA-6804760 Regulation of TP53 Activity through Methylation 16/4506 19/10654 2.2001362084591745e-4 6.271962933726154e-4 2.9600368750123436e-4 11200/472/4194/56950/7314/7157/6233/10419/26013/7311/7316/2033/91875/133746/10919/4193 16 Bunyavirus R-HSA-8851708 Signaling by FGFR2 IIIa TM 16/4506 19/10654 2.2001362084591745e-4 6.271962933726154e-4 2.9600368750123436e-4 5431/5435/5433/5439/5438/2963/5434/5436/2962/5432/22916/5440/5430/5441/4686/5437 16 Bunyavirus R-HSA-75893 TNF signaling 30/4506 43/10654 2.4410755424229277e-4 6.944610828852165e-4 3.2774913297837376e-4 7124/9530/8439/10616/1540/3551/7314/90268/81858/8737/55072/23118/841/8517/8887/7128/10454/6233/8772/331/8717/330/7311/1147/7186/6885/7316/329/9099/7185 30 Bunyavirus R-HSA-5205647 Mitophagy 22/4506 29/10654 2.4910566038011643e-4 7.057993710769966e-4 3.33100209109056e-4 9927/65018/1459/8878/1460/9474/1457/84557/7314/139341/192111/6714/8408/6233/9804/7416/7311/401505/10452/7316/56993/81631 22 Bunyavirus R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 22/4506 29/10654 2.4910566038011643e-4 7.057993710769966e-4 3.33100209109056e-4 2308/84676/4089/4088/3630/56729/847/3484/3066/5105/4303/23410/4287/2908/6648/4087/25942/2309/6720/3065/91584/10891 22 Bunyavirus R-HSA-1295596 Spry regulation of FGF signaling 14/4506 16/10654 2.556831148473327e-4 7.184082054559266e-4 3.390509162651621e-4 2885/5518/7314/5515/5594/6714/6233/5781/673/7311/5595/5516/7316/867 14 Bunyavirus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 14/4506 16/10654 2.556831148473327e-4 7.184082054559266e-4 3.390509162651621e-4 7040/7314/7046/2280/6233/57530/5590/7048/7311/387/57154/50855/7316/56288 14 Bunyavirus R-HSA-9614657 FOXO-mediated transcription of cell death genes 14/4506 16/10654 2.556831148473327e-4 7.184082054559266e-4 3.390509162651621e-4 2308/65018/356/1387/4801/604/4303/4800/6794/2309/10018/4802/1649/2033 14 Bunyavirus R-HSA-203927 MicroRNA (miRNA) biogenesis 19/4506 24/10654 2.575705981414335e-4 7.184082054559266e-4 3.390509162651621e-4 5431/5435/5433/5439/192669/29102/5438/54487/26523/5434/5436/5901/5432/27161/5440/5430/5441/192670/5437 19 Bunyavirus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 19/4506 24/10654 2.575705981414335e-4 7.184082054559266e-4 3.390509162651621e-4 374/7039/1839/5594/2069/10000/595/7514/2353/5747/208/1956/5595/596/685/2309/207/1027/1950 19 Bunyavirus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 12/4506 13/10654 2.576786963615232e-4 7.184082054559266e-4 3.390509162651621e-4 2064/9542/7314/2065/9101/10000/6233/3084/208/7311/207/7316 12 Bunyavirus R-HSA-179812 GRB2 events in EGFR signaling 12/4506 13/10654 2.576786963615232e-4 7.184082054559266e-4 3.390509162651621e-4 374/4893/7039/2885/3845/3265/1839/2069/6654/1956/685/1950 12 Bunyavirus R-HSA-209543 p75NTR recruits signalling complexes 12/4506 13/10654 2.576786963615232e-4 7.184082054559266e-4 3.390509162651621e-4 8878/3654/3551/7314/6233/7189/7311/4804/5584/4615/7316/4803 12 Bunyavirus R-HSA-199418 Negative regulation of the PI3K/AKT network 65/4506 110/10654 2.6776781763254286e-4 7.450465823947399e-4 3.5162283017194936e-4 5295/374/23035/5526/7039/2064/145957/2534/3630/3654/9542/2885/8660/5518/5879/5515/23396/1839/5290/3667/6801/2065/3815/5594/2069/8074/57761/8395/2260/5528/6714/2099/5519/10000/7409/3932/8394/5781/4233/8503/5159/3084/5529/7189/208/10718/1956/2549/5595/5516/685/5525/207/4615/2100/1950/50852/2261/2255/391/5728/2066/5527/4254/5296 65 Bunyavirus R-HSA-429914 Deadenylation-dependent mRNA decay 37/4506 56/10654 2.7375181499945966e-4 7.601793428471051e-4 3.5876469778708806e-4 5393/26986/28960/25904/1973/57472/85456/80349/51690/11157/1981/1977/23016/9924/23644/27258/4850/57819/4848/23019/23658/1975/56915/1974/167227/22894/1656/27257/4849/25804/9337/55802/196513/9775/54464/6499/54512 37 Bunyavirus R-HSA-1236394 Signaling by ERBB4 38/4506 58/10654 0.00029451522794791003 8.162111883884425e-4 3.85208784069151e-4 5295/4893/51741/23385/4734/10413/145957/83737/9542/2885/3845/3265/7314/1839/5290/2065/2069/23118/348/11059/6714/2099/3925/6233/5663/2554/6464/5241/3084/6654/10718/7311/1956/685/7316/1950/9611/2066 38 Bunyavirus R-HSA-5689896 Ovarian tumor domain proteases 27/4506 38/10654 3.115374082178381e-4 8.616729108247347e-4 4.0666432776973436e-4 7321/55432/324/7187/7314/8737/55611/8517/80124/983/2099/23586/7128/7157/6233/10318/7706/79155/64127/7189/7311/387/10392/57506/7316/7415/5728 27 Bunyavirus R-HSA-182971 EGFR downregulation 23/4506 31/10654 3.1520252427258194e-4 8.700837996752063e-4 4.1063382526391605e-4 374/7039/6456/30011/2885/7314/1839/2060/2069/9146/6233/29924/5782/998/7311/1956/685/58513/7316/1950/867/5774/10254 23 Bunyavirus R-HSA-157858 Gap junction trafficking and regulation 33/4506 49/10654 3.415703830675978e-4 9.391501262253082e-4 4.43229501541054e-4 71/2705/51807/1212/347688/1785/2697/10381/7278/7846/113457/81027/1759/79861/4646/1601/7082/6714/10376/1213/1211/375519/1173/84617/10382/7277/347733/2700/10383/60/84790/7280/112714 33 Bunyavirus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 33/4506 49/10654 3.415703830675978e-4 9.391501262253082e-4 4.43229501541054e-4 9134/2810/1869/6790/25904/8900/55835/57472/144455/85456/7027/898/890/10769/983/7157/4869/4850/891/5111/4848/23019/1874/1017/4849/1027/9337/1026/2033/995/10498/581/3276 33 Bunyavirus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 17/4506 21/10654 3.4394606519831276e-4 9.419662374979331e-4 4.445585580579991e-4 4790/4792/1660/3551/11035/8737/29110/8517/5970/3661/4791/23220/7098/1147/147945/4615/4793 17 Bunyavirus R-HSA-500657 Presynaptic function of Kainate receptors 17/4506 21/10654 3.4394606519831276e-4 9.419662374979331e-4 4.445585580579991e-4 2788/2782/2787/10681/2792/2785/2783/2784/2791/2786/54331/59345/51764/94235/55970/2793/2790 17 Bunyavirus R-HSA-111885 Opioid Signalling 55/4506 91/10654 3.5184581253928715e-4 9.617118876073849e-4 4.538774671559432e-4 2788/2770/817/5578/5582/2775/5530/3709/2782/5499/5518/814/2773/5515/2787/818/5567/5594/10681/5528/2792/5519/2785/2783/2784/5613/2771/5580/3710/801/2791/805/3838/10645/5566/84254/816/2786/5577/1020/5516/5533/815/5321/54331/59345/51764/94235/3708/55970/10768/2793/5576/5534/2790 55 Bunyavirus R-HSA-5620920 Cargo trafficking to the periciliary membrane 34/4506 51/10654 3.7345092537069044e-4 0.0010187682778214139 4.808050846774777e-4 55763/79738/123016/10576/60412/6010/54585/166379/10575/8729/11336/117177/378/56623/4218/582/6753/585/583/22948/55770/23265/10694/10640/7203/8766/149371/6950/55212/54536/92482/8195/129880/27241 34 Bunyavirus R-HSA-5357905 Regulation of TNFR1 signaling 24/4506 33/10654 3.852153663961142e-4 0.0010488090249144203 4.949827384818491e-4 7124/10616/1540/3551/7314/90268/81858/8737/55072/841/8517/8887/7128/6233/331/8717/330/7311/1147/7186/7316/329/9099/7185 24 Bunyavirus R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 29/4506 42/10654 4.0901630861009256e-4 0.0011114400276851248 5.245412801504214e-4 2788/2740/3709/2782/8826/2787/5567/10681/2792/2785/2783/2784/3710/2791/5566/2786/5577/54331/59345/51764/94235/3708/3790/55970/2778/2793/5576/5906/2790 29 Bunyavirus R-HSA-5675482 Regulation of necroptotic cell death 15/4506 18/10654 4.424326854868679e-4 0.001196536587947458 5.647023842536898e-4 356/7314/8737/841/6233/8772/331/8717/330/8837/7311/7186/355/7316/329 15 Bunyavirus R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 15/4506 18/10654 4.424326854868679e-4 0.001196536587947458 5.647023842536898e-4 4893/5578/2885/6196/6197/3845/3265/1839/5594/5598/6195/6654/1956/5595/4314 15 Bunyavirus R-HSA-201681 TCF dependent signaling in response to WNT 124/4506 233/10654 4.4290737401785394e-4 0.001196536587947458 5.647023842536898e-4 56998/9070/5689/857/5682/1459/5526/1452/5929/1460/143471/5705/6657/8452/55366/5709/9978/5695/1457/4609/5711/1387/5683/324/5699/8312/5702/1855/6932/5518/25776/6659/80351/5696/5691/7314/5515/5718/51176/8945/5700/122706/5707/1856/1454/23198/9101/8395/7534/5528/7091/83439/59349/9861/81847/5519/2932/5698/5692/5713/5710/8313/5719/6233/1857/7514/7089/331/8607/4221/123169/7090/6597/864/4041/79577/5706/8658/5714/6934/10524/5688/5687/607/5708/5529/7088/208/57680/5704/7311/5694/5516/5684/8295/5720/7015/1487/1499/5525/139285/207/5690/5717/9491/10197/64750/7316/10213/5715/5701/1455/5685/5686/2033/54894/3065/5527/5716/23072/9736/5693/5721/6259 124 Bunyavirus R-HSA-202040 G-protein activation 21/4506 28/10654 4.529502956162567e-4 0.0012189434596313936 5.752772500714499e-4 2788/2770/2775/2782/2773/2787/10681/2792/2785/2783/2784/2771/2791/2786/54331/59345/51764/94235/55970/2793/2790 21 Bunyavirus R-HSA-69205 G1/S-Specific Transcription 21/4506 28/10654 4.529502956162567e-4 0.0012189434596313936 5.752772500714499e-4 5422/1869/4998/5928/990/8900/6241/7027/898/1876/983/7298/1719/26271/8318/5111/1874/81620/55957/3065/7083 21 Bunyavirus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 18/4506 23/10654 4.881102787024876e-4 0.0013085110163678225 6.175484295324995e-4 7321/8239/4089/23327/4088/7314/6497/51592/7323/6233/142/4087/7311/64750/54778/7316/9611/3065 18 Bunyavirus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 18/4506 23/10654 4.881102787024876e-4 0.0013085110163678225 6.175484295324995e-4 3654/7334/7314/23118/8517/10454/6233/64127/5602/3656/7189/7311/6416/6885/10392/7316/5609/5599 18 Bunyavirus R-HSA-5693538 Homology Directed Repair 78/4506 138/10654 4.919696799037222e-4 0.0013163257846176366 6.212365894329253e-4 2237/151987/5892/9156/7486/5982/472/6613/80198/4683/165918/84126/8900/8924/672/6117/7334/348654/7314/6118/25/5888/51588/51720/63967/5531/890/7517/9656/84464/5985/5984/6233/7158/6047/5884/5810/5424/7515/54107/580/11073/5425/641/5111/6119/3364/10524/5427/5429/142/1111/7329/7311/3980/5983/10038/56655/51750/1017/54962/5893/5883/10111/675/51548/545/7336/29086/7316/5426/10635/7341/8914/5932/9025/79184/5981 78 Bunyavirus R-HSA-430039 mRNA decay by 5' to 3' exoribonuclease 13/4506 15/10654 5.334180880541514e-4 0.001421768288236113 6.709999094975238e-4 51690/11157/23644/27258/57819/23658/167227/1656/27257/25804/55802/196513/54464 13 Bunyavirus R-HSA-5099900 WNT5A-dependent internalization of FZD4 13/4506 15/10654 5.334180880541514e-4 0.001421768288236113 6.709999094975238e-4 5579/5578/1212/5582/163/161/1856/1213/1211/1175/1173/409/160 13 Bunyavirus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 32/4506 48/10654 5.530494198689547e-4 0.001471280326903288 6.943669895903912e-4 5295/3558/3717/2534/2885/9846/1399/7314/5290/7534/3718/6233/7525/7409/6777/5781/6464/6850/5566/8503/4067/29760/3636/6654/3716/7311/7316/3560/3055/867/1398/5296 32 Bunyavirus R-HSA-190873 Gap junction degradation 11/4506 12/10654 5.656371128117074e-4 0.0014933676804157578 7.04791059623838e-4 71/1212/1785/2697/1759/4646/1601/1213/1211/1173/60 11 Bunyavirus R-HSA-2029481 FCGR activation 11/4506 12/10654 5.656371128117074e-4 0.0014933676804157578 7.04791059623838e-4 2268/2534/6714/7525/2214/2209/6850/4067/3055/917/2212 11 Bunyavirus R-HSA-381033 ATF6 (ATF6-alpha) activates chaperones 11/4506 12/10654 5.656371128117074e-4 0.0014933676804157578 7.04791059623838e-4 811/3309/4801/8720/468/7184/7494/4800/22926/4802/1649 11 Bunyavirus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 11/4506 12/10654 5.656371128117074e-4 0.0014933676804157578 7.04791059623838e-4 7187/7314/29110/3661/6233/10010/3665/7098/7311/9641/7316 11 Bunyavirus R-HSA-9006115 Signaling by NTRK2 (TRKB) 19/4506 25/10654 6.469072251811346e-4 0.00170470448374764 8.045309237652158e-4 5295/4893/5335/2534/2885/3845/3265/5879/5290/6714/5781/6464/7074/6654/2549/1020/4915/10817/8851 19 Bunyavirus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 60/4506 103/10654 7.586169952415484e-4 0.0019953058327673934 9.416794876384663e-4 5295/374/5526/7039/2064/145957/2534/3630/3654/9542/2885/8660/5518/5879/5515/23396/1839/5290/3667/6801/2065/3815/5594/2069/8074/8395/2260/5528/6714/2099/5519/7409/3932/8394/5781/4233/8503/5159/3084/5529/7189/10718/1956/2549/5595/5516/685/5525/207/4615/2100/1950/50852/2261/2255/391/2066/5527/4254/5296 60 Bunyavirus R-HSA-354192 Integrin alphaIIb beta3 signaling 20/4506 27/10654 8.150857883747075e-4 0.0021317628311338507 0.001006080019224237 5770/2244/3690/2885/9564/7094/6714/2335/1445/2266/2243/5170/6464/5747/6850/6654/7450/207/1398/5906 20 Bunyavirus R-HSA-76066 RNA Polymerase III Transcription Initiation From Type 2 Promoter 20/4506 27/10654 8.150857883747075e-4 0.0021317628311338507 0.001006080019224237 55718/2976/5435/9328/9330/2972/2975/55814/11128/9533/5434/10623/9329/6908/171568/5440/5441/51082/55703/5437 20 Bunyavirus R-HSA-9006921 Integrin signaling 20/4506 27/10654 8.150857883747075e-4 0.0021317628311338507 0.001006080019224237 5770/2244/3690/2885/9564/7094/6714/2335/1445/2266/2243/5170/6464/5747/6850/6654/7450/207/1398/5906 20 Bunyavirus R-HSA-416993 Trafficking of GluR2-containing AMPA receptors 14/4506 17/10654 8.812960669652648e-4 0.0022963116212141666 0.001083738400104851 5579/23426/5578/5582/163/161/2892/1175/2891/1173/2890/160/2893/4905 14 Bunyavirus R-HSA-432142 Platelet sensitization by LDL 14/4506 17/10654 8.812960669652648e-4 0.0022963116212141666 0.001083738400104851 5526/2268/1432/5518/5515/5528/5519/5781/338/5529/5516/5321/5525/5527 14 Bunyavirus R-HSA-190828 Gap junction trafficking 31/4506 47/10654 8.8719417432932e-4 0.002307366938460955 0.0010889559288213375 71/2705/51807/1212/347688/1785/2697/10381/7278/7846/113457/81027/1759/79861/4646/1601/10376/1213/1211/375519/1173/84617/10382/7277/347733/2700/10383/60/84790/7280/112714 31 Bunyavirus R-HSA-9613829 Chaperone Mediated Autophagy 17/4506 22/10654 9.153925454298663e-4 0.0023762704065721295 0.0011214747444745006 1915/5116/3043/3920/3312/11315/7314/10013/6233/8100/3326/7311/1080/7316/10226/3320/7431 17 Bunyavirus R-HSA-186763 Downstream signal transduction 21/4506 29/10654 9.880424631111212e-4 0.0025553454426287627 0.0012059887500135745 5295/4893/5335/2885/9564/3845/3265/1399/5290/5921/6778/6714/6777/5781/6774/6772/5159/6654/4690/1398/5296 21 Bunyavirus R-HSA-72086 mRNA Capping 21/4506 29/10654 9.880424631111212e-4 0.0025553454426287627 0.0012059887500135745 5431/5435/5433/8732/5439/5438/6829/2963/5434/5436/4331/2962/5432/22916/5440/5430/5441/4686/8731/5437/1022 21 Bunyavirus R-HSA-877300 Interferon gamma signaling 54/4506 92/10654 0.0010688338761316227 0.002759174858013856 0.0013021855216028542 960/5770/817/3383/3115/4684/6672/3113/3106/3459/3717/3117/117854/3127/818/7412/9830/3126/2634/10612/3458/3661/5580/10107/4940/5781/3660/8554/3135/3665/3120/3123/23650/2209/8638/7706/3122/6772/3659/5771/816/3716/3125/3105/3460/815/6737/23321/4281/3119/51127/7341/55128/5724 54 Bunyavirus R-HSA-169893 Prolonged ERK activation events 12/4506 14/10654 0.001103254773105558 0.0028115852901446944 0.001326920491082409 5605/1399/5594/4914/673/7529/5595/5604/57498/4803/1398/5906 12 Bunyavirus R-HSA-174411 Polymerase switching on the C-strand of the telomere 12/4506 14/10654 0.001103254773105558 0.0028115852901446944 0.001326920491082409 5982/5422/5558/5557/5985/5984/23649/5424/5425/5111/5983/5981 12 Bunyavirus R-HSA-399955 SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion 12/4506 14/10654 0.001103254773105558 0.0028115852901446944 0.001326920491082409 5361/8829/2534/5362/5879/27289/23396/7094/10371/55558/91584/2242 12 Bunyavirus R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 12/4506 14/10654 0.001103254773105558 0.0028115852901446944 0.001326920491082409 4436/9156/6117/6118/3978/5424/2956/4292/5425/5111/6119/5395 12 Bunyavirus R-HSA-69091 Polymerase switching 12/4506 14/10654 0.001103254773105558 0.0028115852901446944 0.001326920491082409 5982/5422/5558/5557/5985/5984/23649/5424/5425/5111/5983/5981 12 Bunyavirus R-HSA-69109 Leading Strand Synthesis 12/4506 14/10654 0.001103254773105558 0.0028115852901446944 0.001326920491082409 5982/5422/5558/5557/5985/5984/23649/5424/5425/5111/5983/5981 12 Bunyavirus R-HSA-9027284 Erythropoietin activates RAS 12/4506 14/10654 0.001103254773105558 0.0028115852901446944 0.001326920491082409 4893/3717/2885/2056/8660/3845/3265/1399/7409/6464/4067/6654 12 Bunyavirus R-HSA-2426168 Activation of gene expression by SREBF (SREBP) 28/4506 42/10654 0.0012185348969336648 0.003099703734170673 0.0014628972542903198 79718/1387/4801/10499/23054/31/5465/2222/3157/6667/3156/6604/6319/6721/4800/57678/32/1595/4047/4802/79071/6720/2194/6256/10498/3422/4520/8648 28 Bunyavirus R-HSA-196025 Formation of annular gap junctions 10/4506 11/10654 0.0012338278776858874 0.0031158624302429837 0.0014705233095989314 71/1212/1785/2697/1759/1601/1213/1211/1173/60 10 Bunyavirus R-HSA-68689 CDC6 association with the ORC:origin complex 10/4506 11/10654 0.0012338278776858874 0.0031158624302429837 0.0014705233095989314 1869/84515/4998/990/5001/23594/4999/5000/23595/1871 10 Bunyavirus R-HSA-77588 SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs 10/4506 11/10654 0.0012338278776858874 0.0031158624302429837 0.0014705233095989314 6636/6635/7884/84967/6637/22916/25888/4686/6634/6628 10 Bunyavirus R-HSA-8934903 Receptor Mediated Mitophagy 10/4506 11/10654 0.0012338278776858874 0.0031158624302429837 0.0014705233095989314 1459/1460/9474/1457/84557/139341/192111/6714/8408/81631 10 Bunyavirus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 29/4506 44/10654 0.0013166936865318317 0.0033191157306064617 0.0015664481851763489 892/7321/8239/4609/4089/22938/23327/4088/904/7314/5054/7027/6497/51592/7323/6667/6233/1025/4221/1874/142/4087/7311/64750/54778/7316/9611/3065/25937 29 Bunyavirus R-HSA-2559585 Oncogene Induced Senescence 23/4506 33/10654 0.0013336004487501058 0.003343595369707999 0.001578001288278713 27327/5925/1869/4194/192669/4343/7314/7027/5594/6667/7157/6233/26523/1019/1029/7311/3397/5595/192670/7316/1871/1021/4193 23 Bunyavirus R-HSA-2871809 FCERI mediated Ca+2 mobilization 23/4506 33/10654 0.0013336004487501058 0.003343595369707999 0.001578001288278713 5335/5530/3709/2885/4773/7410/7409/3702/3710/801/805/6464/4772/3937/6850/4067/695/6654/9402/3708/10768/5534/2207 23 Bunyavirus R-HSA-9022692 Regulation of MECP2 expression and activity 23/4506 33/10654 0.0013336004487501058 0.003343595369707999 0.001578001288278713 79718/817/9212/27327/192669/4343/814/818/3066/26523/801/805/3930/5566/816/25942/27161/815/8841/192670/9611/3064/3065 23 Bunyavirus R-HSA-432720 Lysosome Vesicle Biogenesis 24/4506 35/10654 0.0015006338725812108 0.003755625885777752 0.001772458037160081 8906/162/27243/1212/1174/1785/408/6456/3312/9146/4074/6844/1213/1211/8907/351/9829/8673/164/1777/1522/2799/81567/375 24 Bunyavirus R-HSA-381070 IRE1alpha activates chaperones 33/4506 52/10654 0.0016526615793392653 0.004128692189245405 0.0019485257254990397 10525/2673/5526/9570/55738/10130/3309/6745/9820/9695/7094/58477/22872/51726/3068/7466/2931/1200/6464/37/7494/118/84447/5611/1639/11015/4189/4000/10113/2081/30827/10106/7709 33 Bunyavirus R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 73/4506 132/10654 0.0016638070763101522 0.004149100294054298 0.001958157278399106 151987/5892/9156/7486/5982/472/6613/80198/4683/165918/84126/8900/8924/672/6117/7334/348654/7314/6118/25/5888/51588/51720/63967/5531/890/7517/9656/84464/5985/5984/6233/7158/6047/5884/5810/5424/54107/580/11073/5425/641/5111/6119/3364/10524/5427/5429/1111/7329/7311/5983/56655/51750/1017/54962/5893/5883/10111/675/51548/545/7336/29086/7316/5426/10635/7341/8914/5932/9025/79184/5981 73 Bunyavirus R-HSA-6807004 Negative regulation of MET activity 16/4506 21/10654 0.0016972178746197152 0.00422486020932122 0.0019939119767618837 5770/6456/30011/2885/7314/2060/9101/9146/6233/4233/5771/7311/26018/7316/867/10254 16 Bunyavirus R-HSA-350054 Notch-HLH transcription pathway 20/4506 28/10654 0.001720424520270844 0.004259807781985002 0.002010405394352206 79718/9759/22938/1387/79885/2648/9734/55869/51564/10013/83933/8850/3066/10014/4855/4851/8841/9611/3065/3516 20 Bunyavirus R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 20/4506 28/10654 0.001720424520270844 0.004259807781985002 0.002010405394352206 2788/2770/2782/2787/10681/2792/2785/2783/2784/2771/2791/775/2786/54331/59345/51764/94235/55970/2793/2790 20 Bunyavirus R-HSA-76061 RNA Polymerase III Transcription Initiation From Type 1 Promoter 20/4506 28/10654 0.001720424520270844 0.004259807781985002 0.002010405394352206 55718/2976/5435/9328/9330/2972/2975/55814/11128/9533/5434/10623/9329/6908/171568/5440/5441/51082/55703/5437 20 Bunyavirus R-HSA-2559583 Cellular Senescence 103/4506 195/10654 0.0017962031576894187 0.004439551776274911 0.002095235113019572 1912/3725/9134/11065/4790/7321/6045/8697/27327/80012/7295/5925/472/1869/1911/26277/4194/5928/1432/4683/23512/192669/8900/51529/4001/29945/8091/51434/6196/4343/6197/29882/4217/54386/3569/7314/996/7014/5606/7027/2146/5594/898/890/5970/9261/6667/51433/5598/84733/119504/6195/7157/7324/64682/6233/2353/8726/26523/1019/9448/246184/1029/8535/5931/7013/1051/50488/8881/6774/3552/10524/5602/10393/51343/7311/25906/3397/57634/648/23466/6416/5595/1017/25913/3159/7290/10111/1027/192670/3490/7316/1026/1871/65057/1021/25842/23135/5609/5599/10919/4193/23043 103 Bunyavirus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 36/4506 58/10654 0.001841669383131025 0.0045119281548060605 0.0021293929598684503 8454/79718/892/23385/9978/9759/4609/22938/1387/57534/7314/79885/2648/9734/55869/51564/3280/10013/83933/102/8850/3066/6233/5663/10014/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 36 Bunyavirus R-HSA-2644603 Signaling by NOTCH1 in Cancer 36/4506 58/10654 0.001841669383131025 0.0045119281548060605 0.0021293929598684503 8454/79718/892/23385/9978/9759/4609/22938/1387/57534/7314/79885/2648/9734/55869/51564/3280/10013/83933/102/8850/3066/6233/5663/10014/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 36 Bunyavirus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 36/4506 58/10654 0.001841669383131025 0.0045119281548060605 0.0021293929598684503 8454/79718/892/23385/9978/9759/4609/22938/1387/57534/7314/79885/2648/9734/55869/51564/3280/10013/83933/102/8850/3066/6233/5663/10014/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 36 Bunyavirus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 36/4506 58/10654 0.001841669383131025 0.0045119281548060605 0.0021293929598684503 8454/79718/892/23385/9978/9759/4609/22938/1387/57534/7314/79885/2648/9734/55869/51564/3280/10013/83933/102/8850/3066/6233/5663/10014/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 36 Bunyavirus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 36/4506 58/10654 0.001841669383131025 0.0045119281548060605 0.0021293929598684503 8454/79718/892/23385/9978/9759/4609/22938/1387/57534/7314/79885/2648/9734/55869/51564/3280/10013/83933/102/8850/3066/6233/5663/10014/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 36 Bunyavirus R-HSA-163685 Integration of energy metabolism 61/4506 108/10654 0.001976523297607968 0.004833813117307908 0.002281305745161552 2788/6804/5563/5313/2740/2770/5578/3709/2782/3630/2776/8826/5518/31/2181/5515/2787/5567/1131/10681/5528/2792/5519/51085/2785/2783/2784/2771/9370/7086/6844/2182/3710/2791/6616/5566/775/32/6794/2786/5577/6888/6812/5516/54331/59345/51764/94235/3708/4082/3790/55970/2778/2194/2767/10768/2793/5576/47/5906/2790 61 Chikungunya_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 13/72 182/10654 2.0221509548176759e-10 1.0138340692098372e-7 5.51941763742591e-8 6045/8021/9883/2099/9972/4927/3066/7157/4792/4193/23512/648/23636 13 Chikungunya_virus R-HSA-2990846 SUMOylation 13/72 188/10654 3.030894078355268e-10 1.0138340692098372e-7 5.51941763742591e-8 6045/8021/9883/2099/9972/4927/3066/7157/4792/4193/23512/648/23636 13 Chikungunya_virus R-HSA-4551638 SUMOylation of chromatin organization proteins 9/72 71/10654 9.368700784887713e-10 2.08922027502996e-7 1.1373931479197014e-7 6045/8021/9883/9972/4927/3066/23512/648/23636 9 Chikungunya_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 9/72 80/10654 2.780104674873094e-9 4.64972506872525e-7 2.531358467121291e-7 7316/7706/5300/8021/9883/9972/4927/4940/23636 9 Chikungunya_virus R-HSA-5688426 Deubiquitination 14/72 297/10654 8.80659292466342e-9 1.1783221333199658e-6 6.414907688281145e-7 7316/5728/1540/409/7706/5698/2099/9100/9097/7157/7415/4792/51720/4193 14 Chikungunya_virus R-HSA-1257604 PIP3 activates AKT signaling 13/72 264/10654 1.9044362839426957e-8 2.0702094809143426e-6 1.1270434747798955e-6 5295/7316/5728/6045/5698/2099/3066/5978/7157/4193/11060/23512/648 13 Chikungunya_virus R-HSA-4570464 SUMOylation of RNA binding proteins 7/72 47/10654 2.42372828689399e-8 2.0702094809143426e-6 1.1270434747798955e-6 6045/8021/9883/9972/4927/648/23636 7 Chikungunya_virus R-HSA-1169408 ISG15 antiviral mechanism 8/72 72/10654 2.4755868232159552e-8 2.0702094809143426e-6 1.1270434747798955e-6 7316/7706/5300/8021/9883/9972/4927/23636 8 Chikungunya_virus R-HSA-6807070 PTEN Regulation 10/72 140/10654 2.9780098167077097e-8 2.2136539637527307e-6 1.205136136351892e-6 7316/5728/6045/5698/3066/5978/7157/11060/23512/648 10 Chikungunya_virus R-HSA-913531 Interferon Signaling 11/72 199/10654 8.18651775193839e-8 5.290238326784615e-6 2.8800605161945983e-6 10437/7316/7706/5300/8021/9883/9972/9830/4927/4940/23636 11 Chikungunya_virus R-HSA-2262752 Cellular responses to stress 16/72 479/10654 8.698448668853627e-8 5.290238326784615e-6 2.8800605161945983e-6 7316/6045/1017/8021/7014/9883/5698/9972/768/4927/7157/7415/4193/23512/648/23636 16 Chikungunya_virus R-HSA-9006925 Intracellular signaling by second messengers 13/72 305/10654 1.0452102520060133e-7 5.827047154933524e-6 3.1723047999480753e-6 5295/7316/5728/6045/5698/2099/3066/5978/7157/4193/11060/23512/648 13 Chikungunya_virus R-HSA-8953897 Cellular responses to external stimuli 16/72 493/10654 1.2929445469888207e-7 6.653691553350161e-6 3.6223385688917573e-6 7316/6045/1017/8021/7014/9883/5698/9972/768/4927/7157/7415/4193/23512/648/23636 16 Chikungunya_virus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 6/72 38/10654 1.793397421866839e-7 7.998552501526103e-6 4.3544947927433436e-6 8021/9883/9972/4927/4193/23636 6 Chikungunya_virus R-HSA-5689896 Ovarian tumor domain proteases 6/72 38/10654 1.793397421866839e-7 7.998552501526103e-6 4.3544947927433436e-6 7316/5728/7706/2099/7157/7415 6 Chikungunya_virus R-HSA-168273 Influenza Viral RNA Transcription and Replication 9/72 134/10654 2.618895250423355e-7 1.0950255765832653e-5 5.961432609516322e-6 8021/6194/200916/9883/6134/9972/4927/6123/23636 9 Chikungunya_virus R-HSA-168255 Influenza Life Cycle 9/72 144/10654 4.837369075616823e-7 1.9036470068162674e-5 1.0363651394200751e-5 8021/6194/200916/9883/6134/9972/4927/6123/23636 9 Chikungunya_virus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 11/72 244/10654 6.396160970290241e-7 2.377239827291206e-5 1.294193974105511e-5 6625/22938/8021/3178/9883/9972/9343/4927/1994/23636/10594 11 Chikungunya_virus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 7/72 77/10654 7.892333239501328e-7 2.778932072224415e-5 1.5128793910623045e-5 6045/8021/9883/9972/4927/648/23636 7 Chikungunya_virus R-HSA-168254 Influenza Infection 9/72 155/10654 9.010139218269199e-7 3.013891568511047e-5 1.6407937734321804e-5 8021/6194/200916/9883/6134/9972/4927/6123/23636 9 Chikungunya_virus R-HSA-5663202 Diseases of signal transduction 13/72 377/10654 1.183028595774362e-6 3.768791097966896e-5 2.0517688929219513e-5 5295/7316/5728/8454/22938/409/5245/5698/2099/3066/3845/7415/4193 13 Chikungunya_virus R-HSA-191859 snRNP Assembly 6/72 53/10654 1.376973101568905e-6 4.005195673693902e-5 2.1804699915004175e-5 8021/9883/9972/4927/79084/23636 6 Chikungunya_virus R-HSA-194441 Metabolism of non-coding RNA 6/72 53/10654 1.376973101568905e-6 4.005195673693902e-5 2.1804699915004175e-5 8021/9883/9972/4927/79084/23636 6 Chikungunya_virus R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 5/72 31/10654 1.8147111646839903e-6 4.496450996939221e-5 2.4479144755581315e-5 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 5/72 31/10654 1.8147111646839903e-6 4.496450996939221e-5 2.4479144755581315e-5 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 5/72 31/10654 1.8147111646839903e-6 4.496450996939221e-5 2.4479144755581315e-5 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 5/72 31/10654 1.8147111646839903e-6 4.496450996939221e-5 2.4479144755581315e-5 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-5689880 Ub-specific processing proteases 10/72 220/10654 2.013426966458889e-6 4.810652287717845e-5 2.618968911258555e-5 7316/5728/1540/409/5698/9100/9097/7157/4792/4193 10 Chikungunya_virus R-HSA-162909 Host Interactions of HIV factors 8/72 129/10654 2.3220193562378963e-6 5.2440710945995244e-5 2.8549265970127223e-5 7316/1025/8021/9883/5698/9972/4927/23636 8 Chikungunya_virus R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 5/72 33/10654 2.5083748135603106e-6 5.2440710945995244e-5 2.8549265970127223e-5 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-180746 Nuclear import of Rev protein 5/72 33/10654 2.5083748135603106e-6 5.2440710945995244e-5 2.8549265970127223e-5 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-180910 Vpr-mediated nuclear import of PICs 5/72 33/10654 2.5083748135603106e-6 5.2440710945995244e-5 2.8549265970127223e-5 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-159227 Transport of the SLBP independent Mature mRNA 5/72 34/10654 2.9254656947706908e-6 5.591818713718834e-5 3.0442440011749148e-5 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-165054 Rev-mediated nuclear export of HIV RNA 5/72 34/10654 2.9254656947706908e-6 5.591818713718834e-5 3.0442440011749148e-5 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-4085377 SUMOylation of SUMOylation proteins 5/72 34/10654 2.9254656947706908e-6 5.591818713718834e-5 3.0442440011749148e-5 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-8943724 Regulation of PTEN gene transcription 6/72 61/10654 3.191651763366344e-6 5.931152860255789e-5 3.228981023756594e-5 6045/3066/5978/7157/23512/648 6 Chikungunya_virus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 5/72 35/10654 3.395186480583782e-6 5.977315146080395e-5 3.2541122500886116e-5 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 5/72 35/10654 3.395186480583782e-6 5.977315146080395e-5 3.2541122500886116e-5 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-176033 Interactions of Vpr with host cellular proteins 5/72 36/10654 3.9221703124143975e-6 6.55982984751308e-5 3.571239284461531e-5 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-177243 Interactions of Rev with host cellular proteins 5/72 36/10654 3.9221703124143975e-6 6.55982984751308e-5 3.571239284461531e-5 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-168276 NS1 Mediated Effects on Host Pathways 5/72 40/10654 6.703710924673624e-6 1.0938494167333304e-4 5.9550294735226545e-5 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 5/72 41/10654 7.594855653526695e-6 1.2097520076688951e-4 6.586015178246208e-5 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-5663205 Infectious disease 12/72 383/10654 8.566181290139914e-6 1.2749811440288013e-4 6.941129349916847e-5 7316/1025/8021/6194/200916/9883/6134/5698/9972/4927/6123/23636 12 Chikungunya_virus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 5/72 42/10654 8.576106349969515e-6 1.2749811440288013e-4 6.941129349916847e-5 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-168253 Host Interactions with Influenza Factors 5/72 42/10654 8.576106349969515e-6 1.2749811440288013e-4 6.941129349916847e-5 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-5654738 Signaling by FGFR2 6/72 73/10654 9.180279245854901e-6 1.335131916408028e-4 7.268596382301595e-5 5295/7316/7073/7072/3178/3845 6 Chikungunya_virus R-HSA-168325 Viral Messenger RNA Synthesis 5/72 43/10654 9.653799232276427e-6 1.3741258907218999e-4 7.480883615605026e-5 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-4615885 SUMOylation of DNA replication proteins 5/72 45/10654 1.2125115462752456e-5 1.6899379676211236e-4 9.200197259018312e-5 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-5619115 Disorders of transmembrane transporters 8/72 176/10654 2.300126210646716e-5 3.140376397801333e-4 1.7096534240252715e-4 7316/8021/9883/5698/9972/4927/7415/23636 8 Chikungunya_virus R-HSA-2980766 Nuclear Envelope Breakdown 5/72 52/10654 2.4863955537267863e-5 3.316221999321884e-4 1.80538559006431e-4 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-190236 Signaling by FGFR 6/72 87/10654 2.5280616138328263e-5 3.316221999321884e-4 1.80538559006431e-4 5295/7316/7073/7072/3178/3845 6 Chikungunya_virus R-HSA-3371556 Cellular response to heat stress 6/72 89/10654 2.878423624142748e-5 3.7032027010605736e-4 2.016061890593909e-4 8021/9883/9972/4927/7415/23636 6 Chikungunya_virus R-HSA-6784531 tRNA processing in the nucleus 5/72 57/10654 3.902219595946023e-5 4.925631905071489e-4 2.681565005357148e-4 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-162599 Late Phase of HIV Life Cycle 7/72 139/10654 4.018119840919684e-5 4.978004025139387e-4 2.710076929743101e-4 7316/1025/8021/9883/9972/4927/23636 7 Chikungunya_virus R-HSA-8878159 Transcriptional regulation by RUNX3 6/72 96/10654 4.424418262716257e-5 5.381701486831229e-4 2.9298540074637803e-4 7316/22938/5698/3845/7157/4193 6 Chikungunya_virus R-HSA-2559583 Cellular Senescence 8/72 195/10654 4.7924185942151024e-5 5.725228642017684e-4 3.1168737473654615e-4 7316/6045/1017/7014/7157/4193/23512/648 8 Chikungunya_virus R-HSA-202424 Downstream TCR signaling 6/72 98/10654 4.970646258531109e-5 5.83396902974967e-4 3.176073140261798e-4 5295/7316/5728/8454/5698/4792 6 Chikungunya_virus R-HSA-162587 HIV Life Cycle 7/72 152/10654 7.102451933319235e-5 8.19231093688029e-4 4.4599788909772335e-4 7316/1025/8021/9883/9972/4927/23636 7 Chikungunya_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 4/72 34/10654 7.628480018499084e-5 8.514235205758564e-4 4.6352377959129313e-4 7316/1540/7706/5300 4 Chikungunya_virus R-HSA-73894 DNA Repair 10/72 334/10654 7.636085386330551e-5 8.514235205758564e-4 4.6352377959129313e-4 7316/10973/7706/1017/7014/10987/9100/7157/7415/51720 10 Chikungunya_virus R-HSA-69563 p53-Dependent G1 DNA Damage Response 5/72 66/10654 7.945597980546619e-5 8.573556530622078e-4 4.667532939336385e-4 7316/1017/5698/7157/4193 5 Chikungunya_virus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 5/72 66/10654 7.945597980546619e-5 8.573556530622078e-4 4.667532939336385e-4 7316/1017/5698/7157/4193 5 Chikungunya_virus R-HSA-69615 G1/S DNA Damage Checkpoints 5/72 68/10654 9.171357196320496e-5 9.73910787990224e-4 5.302071161114272e-4 7316/1017/5698/7157/4193 5 Chikungunya_virus R-HSA-6804757 Regulation of TP53 Degradation 4/72 36/10654 9.591087929550901e-5 0.0010025684101358677 5.458086223066797e-4 7316/1017/7157/4193 4 Chikungunya_virus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 5/72 69/10654 9.836277764062437e-5 0.0010123799729473493 5.511501386826887e-4 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 6/72 112/10654 1.0488301666019976e-4 0.0010631323961465702 5.787802833242284e-4 5295/7316/8454/5698/3845/4792 6 Chikungunya_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 4/72 37/10654 1.0698961785577724e-4 0.0010682993185897756 5.81593209396684e-4 7316/1017/7157/4193 4 Chikungunya_virus R-HSA-70171 Glycolysis 5/72 71/10654 1.1276818118208179e-4 0.0011094399001590105 6.039905679411812e-4 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-1980143 Signaling by NOTCH1 5/72 73/10654 1.2874064614934225e-4 0.00124822452570884 6.795463549606777e-4 7316/8454/22938/409/3066 5 Chikungunya_virus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 4/72 39/10654 1.318911982311688e-4 0.0012605030230950277 6.862308960599161e-4 7316/7706/9100/7415 4 Chikungunya_virus R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 5/72 75/10654 1.4639282143520874e-4 0.0013620037855555326 7.414889620049003e-4 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-202403 TCR signaling 6/72 119/10654 1.4658336705530397e-4 0.0013620037855555326 7.414889620049003e-4 5295/7316/5728/8454/5698/4792 6 Chikungunya_virus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 7/72 171/10654 1.4866239535069064e-4 0.0013623992121864663 7.417042363567263e-4 7316/6194/200916/6134/5698/26986/6123 7 Chikungunya_virus R-HSA-162906 HIV Infection 8/72 233/10654 1.6632410154638892e-4 0.0015036597828991106 8.186079535569071e-4 7316/1025/8021/9883/5698/9972/4927/23636 8 Chikungunya_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 5/72 78/10654 1.7627625991037757e-4 0.001552582904465049 8.452422074500936e-4 7316/1540/7706/5300/4792 5 Chikungunya_virus R-HSA-157118 Signaling by NOTCH 8/72 235/10654 1.763771311499906e-4 0.001552582904465049 8.452422074500936e-4 7316/8454/22938/409/5698/3066/7157/11060 8 Chikungunya_virus R-HSA-2559580 Oxidative Stress Induced Senescence 6/72 125/10654 1.919342293712632e-4 0.0016675844084334426 9.078502168483537e-4 7316/6045/7157/4193/23512/648 6 Chikungunya_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 5/72 83/10654 2.3618263360879646e-4 0.0020257202805677543 0.0011028230935039621 7316/8454/5698/3845/4792 5 Chikungunya_virus R-HSA-72202 Transport of Mature Transcript to Cytoplasm 5/72 84/10654 2.4982227035303507e-4 0.0021155835299516514 0.001151745576844106 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 3/72 19/10654 2.6534883947161087e-4 0.0021648582147135082 0.0011785712253809676 5295/7316/3845 3 Chikungunya_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 3/72 19/10654 2.6534883947161087e-4 0.0021648582147135082 0.0011785712253809676 5295/7316/3845 3 Chikungunya_virus R-HSA-6804760 Regulation of TP53 Activity through Methylation 3/72 19/10654 2.6534883947161087e-4 0.0021648582147135082 0.0011785712253809676 7316/7157/4193 3 Chikungunya_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 4/72 47/10654 2.7459278772309746e-4 0.0022132840359849666 0.001204934743845171 7316/8454/22938/3066 4 Chikungunya_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 6/72 134/10654 2.800279676487605e-4 0.0022302227423454855 0.001214156350958285 5295/7316/8454/5698/3845/4792 6 Chikungunya_virus R-HSA-73893 DNA Damage Bypass 4/72 48/10654 2.980350093589948e-4 0.0023457108383666764 0.001277029266107891 7316/7706/9100/7415 4 Chikungunya_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 5/72 88/10654 3.104627406329255e-4 0.0024151113195747345 0.0013148116065972123 7316/8021/5698/26986/1994 5 Chikungunya_virus R-HSA-70326 Glucose metabolism 5/72 91/10654 3.6281341842756085e-4 0.002789910079632623 0.0015188559319532495 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 5/72 92/10654 3.816669241532504e-4 0.002901536048392324 0.00157962626503618 7316/1017/5300/7157/4193 5 Chikungunya_virus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 5/72 95/10654 4.4269314768048966e-4 0.0033276597280701976 0.001811612408012412 6194/200916/6134/26986/6123 5 Chikungunya_virus R-HSA-5358351 Signaling by Hedgehog 6/72 149/10654 4.945367876457802e-4 0.0036760567881669657 0.002001283374566549 7316/8454/409/5698/8452/7415 6 Chikungunya_virus R-HSA-5619102 SLC transporter disorders 5/72 99/10654 5.351825853877673e-4 0.003934474171696883 0.002141968473616744 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-69541 Stabilization of p53 4/72 57/10654 5.779610947594388e-4 0.004173656664993969 0.0022721818992808016 7316/5698/7157/4193 4 Chikungunya_virus R-HSA-1643713 Signaling by EGFR in Cancer 3/72 25/10654 6.117721207801355e-4 0.004173656664993969 0.0022721818992808016 5295/7316/3845 3 Chikungunya_virus R-HSA-1236394 Signaling by ERBB4 4/72 58/10654 6.176263226224259e-4 0.004173656664993969 0.0022721818992808016 5295/7316/2099/3845 4 Chikungunya_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 4/72 58/10654 6.176263226224259e-4 0.004173656664993969 0.0022721818992808016 7316/8454/22938/3066 4 Chikungunya_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 4/72 58/10654 6.176263226224259e-4 0.004173656664993969 0.0022721818992808016 7316/8454/22938/3066 4 Chikungunya_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 4/72 58/10654 6.176263226224259e-4 0.004173656664993969 0.0022721818992808016 7316/8454/22938/3066 4 Chikungunya_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 4/72 58/10654 6.176263226224259e-4 0.004173656664993969 0.0022721818992808016 7316/8454/22938/3066 4 Chikungunya_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 4/72 58/10654 6.176263226224259e-4 0.004173656664993969 0.0022721818992808016 7316/8454/22938/3066 4 Chikungunya_virus R-HSA-376176 Signaling by ROBO receptors 7/72 218/10654 6.502992533522864e-4 0.004350502004926797 0.0023684583332620117 7316/6194/200916/6134/5698/26986/6123 7 Chikungunya_virus R-HSA-6803529 FGFR2 alternative splicing 3/72 26/10654 6.882272398807345e-4 0.004558653697823875 0.0024817782699190637 7073/7072/3178 3 Chikungunya_virus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 4/72 60/10654 7.026924385787973e-4 0.004608835700090347 0.0025090978714991117 7316/8454/1017/5698 4 Chikungunya_virus R-HSA-5633007 Regulation of TP53 Activity 6/72 160/10654 7.204186721654947e-4 0.004679224191055495 0.0025474180947292918 7316/1017/5300/3066/7157/4193 6 Chikungunya_virus R-HSA-5578749 Transcriptional regulation by small RNAs 5/72 106/10654 7.31112540691206e-4 0.0047030220165617 0.002560373877319406 8021/9883/9972/4927/23636 5 Chikungunya_virus R-HSA-3700989 Transcriptional Regulation by TP53 9/72 365/10654 7.448644488632052e-4 0.004745850631328421 0.0025836902186132235 7316/5728/1025/1017/2810/5300/3066/7157/4193 9 Chikungunya_virus R-HSA-72306 tRNA processing 5/72 107/10654 7.629631594350473e-4 0.004815305223226854 0.0026215020175226053 8021/9883/9972/4927/23636 5 Cottontail_rabbit_papillomavirus R-HSA-3700989 Transcriptional Regulation by TP53 275/1598 365/10654 9.45425751063133e-155 1.2356714566395148e-151 5.92135075665857e-152 23368/6884/1017/23774/6875/834/6118/2176/80010/27161/27113/5563/3725/9891/2963/9134/5434/27165/4436/83990/8621/902/83667/1820/64769/7862/9156/3622/57060/5883/1763/7531/1029/7027/1459/25946/79370/7486/9540/5430/10111/5457/8793/9219/6874/8445/7532/207/10971/55240/9997/22974/133383/9212/57690/204851/7832/4849/6878/1027/58484/4869/3486/5982/51422/7249/27327/898/5931/355/7295/4850/7533/2810/55367/1460/6749/4292/11200/545/472/117584/53632/27244/79813/8794/192670/7534/332/580/8550/11073/9337/5934/639/64065/7316/1869/891/6872/28996/116028/890/80196/2539/84289/1457/54971/4331/10769/983/1026/54205/5366/6790/641/5933/124446/5111/25904/1108/1643/8148/8797/246175/5395/29117/4194/6879/2962/84883/9656/5519/112858/6119/1647/147923/5928/3364/5876/1432/143686/5571/10524/10848/1387/54457/4683/4848/27154/56950/8812/144715/5458/83860/57459/23019/1616/9099/51499/843/28984/10000/6794/2965/5985/54815/51755/2877/2033/995/94241/1874/10128/84126/5728/900/7994/2068/54541/1111/192669/3066/3065/2071/7157/1107/8900/5984/91875/8626/6873/5371/23112/208/10498/10542/6233/5527/2968/2475/672/55571/5932/1025/2353/604/7311/63970/7161/839/6881/5562/51616/5518/1386/55835/6880/6908/10419/5325/8851/5300/7156/581/5983/4343/6117/11198/50484/5600/7159/57472/6883/3276/144455/85456/79733/29883/26523/51497/5564/7874/51230/6882/5052/637/317/5565/1020/138474/133746/5884/5810/53615/10397/1022/8795/665/26155/26013/8178/5875/83695/10919/6877/7529/7296/7314/4193/5515/25920/1263/27166/5516 275 Cottontail_rabbit_papillomavirus R-HSA-5633007 Regulation of TP53 Activity 147/1598 160/10654 1.3165335130285427e-106 8.603546507641527e-104 4.1228286329051734e-104 23368/6884/1017/23774/6875/6118/80010/5563/9891/83990/64769/7862/9156/3622/5883/1763/1029/1459/25946/7486/10111/5457/9219/6874/8445/207/22974/133383/9212/204851/6878/5982/51422/5931/1460/6749/11200/545/472/117584/53632/79813/580/8550/11073/639/7316/6872/28996/116028/890/80196/84289/1457/54971/983/6790/641/1108/8148/29117/4194/6879/5519/112858/6119/5928/3364/1432/5571/10524/10848/54457/4683/27154/56950/144715/5458/83860/57459/1616/9099/10000/6794/5985/54815/2033/94241/84126/900/7994/1111/3066/3065/7157/1107/8900/5984/91875/8626/6873/5371/208/6233/5527/2475/672/5932/7311/7161/6881/5562/51616/5518/6880/6908/10419/8851/5300/7156/5983/6117/11198/5600/7159/6883/5564/7874/51230/6882/5565/1020/138474/133746/5884/5810/53615/26155/26013/83695/10919/6877/7314/4193/5515/1263/5516 147 Cottontail_rabbit_papillomavirus R-HSA-157118 Signaling by NOTCH 163/1598 235/10654 3.7650959700076986e-81 1.640326810933354e-78 7.860463516331864e-79 8454/5718/1999/5689/27161/3725/23129/5684/8841/4242/5720/7090/79718/79885/142678/5682/23509/2648/9734/892/7027/55869/5700/5707/23462/207/51564/4904/487/113878/5690/55534/5045/57690/3280/23220/5717/9491/182/6500/27327/409/84441/3091/51548/10013/23385/5706/3955/5705/10402/10197/10046/192670/7534/488/7316/10213/5709/83933/9978/1950/1869/4854/9611/5695/3714/7091/8650/5986/54492/1272/9759/9612/102/6484/1024/5714/6772/4609/5664/10320/1871/9861/10014/5715/5870/22938/8850/5711/489/5701/5688/1387/5687/8788/4088/2173/5685/6907/5683/5698/5708/59/5692/5686/26508/5713/2033/9148/408/4855/595/55294/5699/6400/5710/4853/5702/192669/3066/3065/7157/7088/83737/861/5719/92737/6868/2683/23112/9794/5704/83464/6233/2324/5716/1385/56983/23493/7311/6487/1840/57534/1956/54567/7089/4343/388585/55851/51107/5694/26523/3516/4851/5693/5663/5721/5696/10959/5691/28514/7314 163 Cottontail_rabbit_papillomavirus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 91/1598 92/10654 8.962223388231312e-75 2.928406492104581e-72 1.4032955042099028e-72 6884/1017/6875/6118/80010/5563/9891/83990/9156/5883/1763/1459/7486/10111/6874/8445/22974/9212/204851/6878/5982/51422/1460/6749/11200/545/472/53632/580/8550/11073/7316/6872/28996/116028/890/1457/6790/641/8148/4194/6879/112858/6119/3364/1432/5571/10524/54457/4683/144715/83860/6794/5985/94241/84126/1111/7157/8900/5984/6873/6233/672/5932/7311/6881/5562/51616/6880/6908/8851/5300/7156/5983/6117/11198/5600/6883/5564/6882/5565/1020/138474/5884/5810/26155/83695/6877/7314/4193/1263 91 Cottontail_rabbit_papillomavirus R-HSA-6807070 PTEN Regulation 116/1598 140/10654 1.1948677316165312e-72 3.123384250445612e-70 1.496729053288076e-70 1912/5718/5689/27161/3725/6591/5684/8841/5720/5682/5468/1822/23186/1459/5700/122706/5707/2146/5978/9112/9219/8535/10273/207/51564/6045/5690/57690/5594/84232/5717/9491/23198/27327/80012/5931/1460/143471/5706/5705/10197/192670/7316/10213/5709/5695/1457/1911/5714/1108/57167/2122/9861/7101/10014/5715/5711/1958/5928/5701/5688/84733/5687/57459/5685/5683/5698/5708/10000/5692/54815/5686/5713/23512/57332/5728/5699/5710/6615/5702/192669/3066/3065/7157/1107/23028/5719/5987/5371/23112/208/10542/5704/6233/2475/5716/57504/7311/1386/331/4343/8726/648/5694/23466/26523/7874/53615/5693/5721/5696/23608/5691/7314/6015/5595 116 Cottontail_rabbit_papillomavirus R-HSA-9013694 Signaling by NOTCH4 80/1598 82/10654 5.3617021759021484e-64 1.1679574573173514e-61 5.596864552038208e-62 8454/5718/5689/5684/5720/5682/2648/5700/5707/23462/207/5690/55534/3280/5717/9491/182/6500/84441/23385/5706/5705/10197/10046/7534/7316/10213/5709/9978/5695/102/5714/5664/9861/5715/22938/8850/5711/5701/5688/1387/5687/4088/5685/5683/5698/5708/59/5692/5686/5713/2033/4855/55294/5699/5710/4853/5702/5719/9794/5704/83464/6233/2324/5716/23493/7311/54567/388585/55851/51107/5694/3516/4851/5693/5663/5721/5696/5691/7314 80 Cottontail_rabbit_papillomavirus R-HSA-5663202 Diseases of signal transduction 193/1598 377/10654 9.555435881894961e-64 1.7841363853766737e-61 8.549600525906017e-62 8454/4000/1147/5718/2308/27123/5689/2963/8805/5434/5684/4893/8841/5290/5720/79718/79885/1487/142678/2309/5682/5604/1499/2648/10018/9734/892/55869/842/5700/3815/122706/5707/5430/23462/207/51564/1452/5690/55534/5594/3280/4303/613/5717/1027/9491/7249/182/23198/6500/409/5908/84441/10533/10013/143471/23385/5706/2064/5705/6199/10197/10046/6776/2100/84447/7316/10213/5709/83933/9978/1950/9611/5695/3714/6774/2263/89780/54492/4233/9759/9612/102/1026/1024/5714/6772/6714/2099/6934/4609/5664/7415/9861/4089/10014/5715/2962/22938/5519/8850/5711/2932/2261/5701/867/5688/1387/5159/5687/7046/3717/4088/2247/5685/6907/3164/5683/5698/5708/10000/3320/5692/5686/26508/5713/324/2033/9148/54894/408/55294/5728/5699/6400/8312/1445/5710/2264/5702/3066/3065/2066/4087/5719/6868/208/9794/5704/83464/6233/5527/2475/5716/7409/1385/23493/7311/8826/3932/5518/57534/6469/1956/54567/60/7040/3845/388585/55851/51107/6777/5694/3265/3516/369/4763/4851/5693/5663/5721/5696/5691/5245/7529/5156/28514/7314/5595/4193/5515/5516 193 Cottontail_rabbit_papillomavirus R-HSA-1257604 PIP3 activates AKT signaling 155/1598 264/10654 7.225960833520904e-62 1.1805413511764775e-59 5.657166705190708e-60 1912/1147/5718/2308/5689/27161/3725/6591/3643/5684/8841/5290/5720/2309/5682/5468/1822/23186/1459/842/5700/3815/122706/5707/2146/5978/9112/9219/8535/10273/207/51564/6045/5690/57690/5594/4303/84232/5717/1027/9491/7249/23198/27327/80012/5931/1460/143471/5706/2064/5705/6199/10197/192670/2100/7316/10213/5709/1950/5695/2263/1457/4233/1026/1911/5714/6714/2099/1108/57167/2122/9861/7101/10014/5715/5519/5711/1958/5928/2932/2261/5701/5688/84733/5159/5687/57459/2247/5685/3164/5683/5698/5708/10000/5692/54815/5686/5713/23512/57332/5728/5699/5710/6615/2264/3630/5702/192669/3066/3065/7157/1107/2066/23028/5719/5987/7189/5371/23112/208/10542/5704/6233/5527/2475/5716/7409/1385/57504/7311/3932/5518/1386/1956/331/4343/8726/648/5694/23466/26523/7874/53615/5693/5721/5696/23608/5691/5156/7314/6015/5595/4193/5515/5516 155 Cottontail_rabbit_papillomavirus R-HSA-1980143 Signaling by NOTCH1 73/1598 73/10654 1.7170138378976665e-61 2.493485651258056e-59 1.1948809749112417e-59 8454/8841/7090/79718/79885/142678/2648/9734/892/55869/23462/51564/113878/55534/3280/23220/182/6500/409/84441/3091/10013/23385/10046/7316/83933/9978/9611/3714/7091/8650/54492/1272/9759/9612/102/1024/4609/5664/10014/22938/8850/1387/8788/6907/26508/2033/9148/408/55294/3066/3065/7088/83737/92737/6868/9794/83464/6233/23493/7311/1840/57534/54567/7089/388585/55851/51107/3516/4851/5663/28514/7314 73 Cottontail_rabbit_papillomavirus R-HSA-9006925 Intracellular signaling by second messengers 163/1598 305/10654 4.0835180383637865e-57 5.337158076141469e-55 2.5575718240278453e-55 1912/1147/5718/2308/5689/27161/3725/6591/3643/3838/5684/8841/5290/5720/2309/5682/5468/1822/23186/1459/842/5700/3815/122706/5707/5567/2146/5978/9112/9219/8535/10273/207/51564/6045/5690/5578/57690/5594/4303/5568/84232/5717/1027/9491/7249/5582/23198/27327/80012/5931/1460/143471/5706/2064/5705/6199/10197/192670/2100/7316/10213/5709/1950/5695/2263/1457/4233/1026/1911/5714/6714/2099/1108/57167/2122/9861/7101/5566/10014/5715/5519/5711/1958/5928/2932/2261/5701/5688/84733/5159/5687/57459/2247/5685/3164/5683/5698/5708/10000/5692/54815/5686/5713/23512/57332/5728/5699/5710/6615/2264/3630/5702/192669/3066/3065/7157/1107/2066/23028/5719/5987/7189/5371/23112/208/10542/5704/6233/5527/5580/2475/5716/7409/1385/57504/7311/3932/5518/1386/1956/331/4343/8726/648/5694/23466/26523/7874/53615/5693/5721/5696/23608/814/5691/5156/7314/6015/5595/4193/5515/5516 163 Cottontail_rabbit_papillomavirus R-HSA-2262752 Cellular responses to stress 211/1598 479/10654 2.059815652509351e-55 2.4474355071179287e-53 1.1728136968833148e-53 1912/5718/1017/3303/6118/5689/3725/9134/1019/5684/5903/5601/5720/573/83667/4790/5241/5606/5682/9631/3159/112399/7531/7290/1029/7027/1915/5700/122706/7321/5707/2146/10111/8535/51807/6045/7422/8697/5690/57690/5594/3308/5717/1027/9491/23198/27327/80012/898/10049/5931/7295/10294/5925/3091/7277/1051/1410/10013/143471/545/5706/472/27244/5705/79813/10197/3337/192670/3576/3313/3490/8550/29855/7316/10213/5709/9978/2114/1869/5695/890/3305/6774/5970/1026/1911/9532/54205/832/6667/5714/4927/7415/1871/51433/9861/4194/1031/5715/6119/5711/5598/3552/5928/10370/1432/2932/5701/10524/5688/1387/84733/4683/5687/57805/7846/3310/2908/5685/5683/3309/5698/5708/3320/5602/5692/5686/5713/2877/2033/23512/1021/7266/57332/6195/5699/5710/25842/3301/7428/5702/192669/10540/7157/8900/6648/23135/5719/64682/8091/23112/5609/8131/10542/5704/6233/51434/3326/2475/5716/3306/2353/1030/51343/6196/7311/367/3397/57634/10383/23411/84790/9529/4343/8726/55662/6117/6197/5599/6396/648/5600/5694/3304/3312/23466/26523/3456/5052/2113/405/3569/5693/5721/5696/7280/2288/5691/8480/10919/768/10728/7296/7314/23523/996/6015/5595/4193/2950 211 Cottontail_rabbit_papillomavirus R-HSA-5663205 Infectious disease 184/1598 383/10654 3.273516638354437e-55 3.565405205274375e-53 1.7085459647551667e-53 6158/6884/5718/3303/6875/5689/6138/8945/6144/2963/3837/3838/6203/5434/5684/5903/9349/4736/7852/5720/902/6194/6191/6128/5606/5682/51121/6132/9631/5604/1499/1938/3159/6147/6129/6217/5700/3843/122706/5707/5430/6874/6230/6222/6152/5690/6136/2060/5045/7520/6878/6125/5717/4869/9491/23198/6500/6749/6154/51065/6141/143471/6202/5706/5705/10197/6232/6160/7316/6155/10213/5709/6175/9978/6218/5695/6872/292/4233/4331/4836/9397/6209/5714/6714/4927/6231/6229/8148/9861/6130/6879/5715/2962/6142/3840/5711/6204/23327/5701/867/5688/54457/8812/5687/83860/999/5685/5683/5698/5708/9146/3320/5692/2965/5686/128866/5713/140801/6156/5699/6143/5710/2068/6181/6124/5702/2071/6207/6873/5719/5609/5704/6233/3326/2968/5716/7514/1025/7311/6223/6881/3932/51616/1213/5610/6880/6908/1211/6188/6189/7040/7251/11198/6396/6135/6201/6883/5694/3304/1104/51497/2547/9045/6882/2961/6187/138474/1022/6168/5693/6208/10254/5721/6137/5696/8178/5691/8480/6122/6877/7296/7314/25920 184 Cottontail_rabbit_papillomavirus R-HSA-8878159 Transcriptional regulation by RUNX3 83/1598 96/10654 3.586779709598207e-55 3.6060931388037357e-53 1.7280436657578408e-53 57154/5718/5689/8463/51176/5684/5720/2309/5682/1499/2648/10018/1029/864/5700/5707/5690/55534/3280/5717/9491/182/84441/5706/5705/6097/10197/10046/64750/6696/7316/10213/5709/5695/9759/1026/5714/6714/6934/4609/9861/4089/5715/22938/8850/5711/5701/5688/1387/5687/4088/5685/5683/5698/5708/5692/5686/5713/2033/595/5699/5710/5702/7157/861/5719/9794/5704/6233/5716/7311/25937/7040/3845/5694/3516/4851/5693/5721/5696/5691/7314/4193 83 Cottontail_rabbit_papillomavirus R-HSA-8878166 Transcriptional regulation by RUNX2 93/1598 121/10654 7.478962501458325e-53 6.700752954880537e-51 3.211007939559392e-51 8454/57154/5718/8493/5689/7291/25/1019/5684/8841/5720/6662/5682/5700/122706/5707/23462/10273/207/5690/5594/3280/5717/9491/23198/6500/4086/5925/10013/143471/5706/5705/10197/7316/10213/5709/9978/891/5695/4094/11059/9759/983/1026/5714/6772/6714/2099/9861/4089/5715/5711/2932/5701/5688/5687/6502/650/2908/5685/5683/5698/5708/10000/5692/5686/5713/595/55294/5699/5710/5702/861/5719/208/5704/6233/5716/23493/7311/25937/367/860/581/5694/5693/5721/5696/5691/117581/10891/7314/5595 93 Cottontail_rabbit_papillomavirus R-HSA-8953897 Cellular responses to external stimuli 211/1598 493/10654 7.690229098944762e-53 6.700752954880537e-51 3.211007939559392e-51 1912/5718/1017/3303/6118/5689/3725/9134/1019/5684/5903/5601/5720/573/83667/4790/5241/5606/5682/9631/3159/112399/7531/7290/1029/7027/1915/5700/122706/7321/5707/2146/10111/8535/51807/6045/7422/8697/5690/57690/5594/3308/5717/1027/9491/23198/27327/80012/898/10049/5931/7295/10294/5925/3091/7277/1051/1410/10013/143471/545/5706/472/27244/5705/79813/10197/3337/192670/3576/3313/3490/8550/29855/7316/10213/5709/9978/2114/1869/5695/890/3305/6774/5970/1026/1911/9532/54205/832/6667/5714/4927/7415/1871/51433/9861/4194/1031/5715/6119/5711/5598/3552/5928/10370/1432/2932/5701/10524/5688/1387/84733/4683/5687/57805/7846/3310/2908/5685/5683/3309/5698/5708/3320/5602/5692/5686/5713/2877/2033/23512/1021/7266/57332/6195/5699/5710/25842/3301/7428/5702/192669/10540/7157/8900/6648/23135/5719/64682/8091/23112/5609/8131/10542/5704/6233/51434/3326/2475/5716/3306/2353/1030/51343/6196/7311/367/3397/57634/10383/23411/84790/9529/4343/8726/55662/6117/6197/5599/6396/648/5600/5694/3304/3312/23466/26523/3456/5052/2113/405/3569/5693/5721/5696/7280/2288/5691/8480/10919/768/10728/7296/7314/23523/996/6015/5595/4193/2950 211 Cottontail_rabbit_papillomavirus R-HSA-453279 Mitotic G1-G1/S phases 103/1598 149/10654 5.1079710272143764e-51 4.172573832855744e-49 1.9995018165740488e-49 8454/5718/1017/4172/6118/5689/25/9134/1019/5684/5720/902/5682/1029/7027/5700/5707/207/5690/5717/1027/9491/6500/7153/898/5925/5706/5705/10197/91768/5934/7316/10213/5709/5422/1869/4174/891/5695/890/4331/983/1026/84515/5933/5714/5111/6714/4609/1871/9861/1031/5715/5519/6119/5711/5928/5701/5688/5687/4067/3717/6502/5685/5683/5698/5708/10000/5692/5686/5713/1021/1874/595/5699/5710/5702/3065/5520/8900/5719/208/5704/6233/5716/1030/7311/5518/6117/1719/5694/7465/1022/5693/5721/5696/7083/5691/1028/7314/5515/6241/5516 103 Cottontail_rabbit_papillomavirus R-HSA-69563 p53-Dependent G1 DNA Damage Response 64/1598 66/10654 9.83803416256335e-51 7.143505916927944e-49 3.423175629663855e-49 5718/1017/5689/9134/5684/5720/5682/57060/1029/25946/5700/122706/5707/5690/5717/1027/9491/23198/898/11200/143471/5706/472/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/8900/5719/5704/6233/5716/7311/5694/51230/5693/5721/5696/5691/7314/4193 64 Cottontail_rabbit_papillomavirus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 64/1598 66/10654 9.83803416256335e-51 7.143505916927944e-49 3.423175629663855e-49 5718/1017/5689/9134/5684/5720/5682/57060/1029/25946/5700/122706/5707/5690/5717/1027/9491/23198/898/11200/143471/5706/472/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/8900/5719/5704/6233/5716/7311/5694/51230/5693/5721/5696/5691/7314/4193 64 Cottontail_rabbit_papillomavirus R-HSA-69615 G1/S DNA Damage Checkpoints 65/1598 68/10654 2.8550858592472053e-50 1.9639985358084723e-48 9.411501862892452e-49 5718/1017/5689/9134/5684/5720/5682/57060/1029/25946/5700/122706/5707/5690/5717/1027/9491/23198/898/11200/143471/5706/472/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/7157/8900/5719/5704/6233/5716/7311/5694/51230/5693/5721/5696/5691/7314/4193 65 Cottontail_rabbit_papillomavirus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 58/1598 58/10654 6.6756110804581645e-49 3.635426534232842e-47 1.7421002600318456e-47 8454/8841/79718/79885/142678/2648/9734/892/55869/23462/51564/55534/3280/182/6500/84441/10013/23385/10046/7316/83933/9978/9611/3714/54492/9759/9612/102/1024/4609/5664/10014/22938/8850/1387/6907/26508/2033/9148/55294/3066/3065/6868/9794/83464/6233/23493/7311/57534/54567/388585/55851/51107/3516/4851/5663/28514/7314 58 Cottontail_rabbit_papillomavirus R-HSA-2644603 Signaling by NOTCH1 in Cancer 58/1598 58/10654 6.6756110804581645e-49 3.635426534232842e-47 1.7421002600318456e-47 8454/8841/79718/79885/142678/2648/9734/892/55869/23462/51564/55534/3280/182/6500/84441/10013/23385/10046/7316/83933/9978/9611/3714/54492/9759/9612/102/1024/4609/5664/10014/22938/8850/1387/6907/26508/2033/9148/55294/3066/3065/6868/9794/83464/6233/23493/7311/57534/54567/388585/55851/51107/3516/4851/5663/28514/7314 58 Cottontail_rabbit_papillomavirus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 58/1598 58/10654 6.6756110804581645e-49 3.635426534232842e-47 1.7421002600318456e-47 8454/8841/79718/79885/142678/2648/9734/892/55869/23462/51564/55534/3280/182/6500/84441/10013/23385/10046/7316/83933/9978/9611/3714/54492/9759/9612/102/1024/4609/5664/10014/22938/8850/1387/6907/26508/2033/9148/55294/3066/3065/6868/9794/83464/6233/23493/7311/57534/54567/388585/55851/51107/3516/4851/5663/28514/7314 58 Cottontail_rabbit_papillomavirus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 58/1598 58/10654 6.6756110804581645e-49 3.635426534232842e-47 1.7421002600318456e-47 8454/8841/79718/79885/142678/2648/9734/892/55869/23462/51564/55534/3280/182/6500/84441/10013/23385/10046/7316/83933/9978/9611/3714/54492/9759/9612/102/1024/4609/5664/10014/22938/8850/1387/6907/26508/2033/9148/55294/3066/3065/6868/9794/83464/6233/23493/7311/57534/54567/388585/55851/51107/3516/4851/5663/28514/7314 58 Cottontail_rabbit_papillomavirus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 58/1598 58/10654 6.6756110804581645e-49 3.635426534232842e-47 1.7421002600318456e-47 8454/8841/79718/79885/142678/2648/9734/892/55869/23462/51564/55534/3280/182/6500/84441/10013/23385/10046/7316/83933/9978/9611/3714/54492/9759/9612/102/1024/4609/5664/10014/22938/8850/1387/6907/26508/2033/9148/55294/3066/3065/6868/9794/83464/6233/23493/7311/57534/54567/388585/55851/51107/3516/4851/5663/28514/7314 58 Cottontail_rabbit_papillomavirus R-HSA-69481 G2/M Checkpoints 108/1598 168/10654 1.1612941445308622e-48 6.071245787607348e-47 2.909347435772055e-47 5718/1017/4172/6118/5689/80010/5684/5720/83990/5682/9156/5883/1763/7531/51512/5700/7486/122706/5707/10111/7532/10971/5690/51588/51720/5717/5982/9491/23198/63967/7533/2810/11200/143471/545/5706/472/5705/10197/7336/7534/580/11073/7316/10213/5709/4174/891/5695/116028/983/84515/641/5714/9861/5715/9656/6119/5711/3364/7341/5701/10524/5688/4683/5687/144715/5685/5683/5698/5708/5692/5985/5686/5713/995/84126/5699/5710/1111/5702/7157/5984/5719/8924/5704/6233/5716/672/5932/7158/7311/79184/7156/5983/6117/7334/5694/7465/5884/5810/5693/5721/5696/83695/5691/7529/7314 108 Cottontail_rabbit_papillomavirus R-HSA-69202 Cyclin E associated events during G1/S transition 72/1598 83/10654 3.55276510734187e-48 1.734998626277532e-46 8.31413186191867e-47 8454/5718/1017/5689/9134/1019/5684/5720/902/5682/7027/5700/5707/207/5690/5717/1027/9491/6500/898/5925/5706/5705/10197/91768/5934/7316/10213/5709/1869/5695/890/4331/1026/5714/4609/9861/5715/5711/5928/5701/5688/5687/6502/5685/5683/5698/5708/10000/5692/5686/5713/1874/595/5699/5710/5702/8900/5719/208/5704/6233/5716/7311/5694/7465/1022/5693/5721/5696/5691/7314 72 Cottontail_rabbit_papillomavirus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 73/1598 85/10654 3.584159365684267e-48 1.734998626277532e-46 8.31413186191867e-47 8454/5718/1017/5689/9134/1019/5684/5720/902/5682/7027/5700/5707/207/5690/5717/1027/9491/6500/898/5925/5706/5705/10197/91768/5934/7316/10213/5709/1869/5695/890/4331/1026/5714/4609/9861/5715/5711/5928/5701/5688/5687/6502/5685/5683/5698/5708/10000/5692/5686/5713/1874/595/5699/5710/5702/8900/5719/208/5704/6233/5716/51343/7311/5694/7465/1022/5693/5721/5696/5691/7314 73 Cottontail_rabbit_papillomavirus R-HSA-5687128 MAPK6/MAPK4 signaling 74/1598 89/10654 9.463366916146383e-47 4.417364485501187e-45 2.1168057575590596e-45 5718/2308/5689/27161/3725/5684/5720/2309/5682/5700/10642/122706/5707/5567/5690/57690/5568/5717/9491/3315/23198/27327/143471/5706/5705/10197/3337/192670/8550/7316/10213/5709/5695/983/5597/5714/4609/9861/5566/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/8555/5702/192669/998/8556/5719/23112/5704/6233/5716/7514/7311/4343/5694/26523/8202/5693/5721/5696/5691/7314 74 Cottontail_rabbit_papillomavirus R-HSA-69620 Cell Cycle Checkpoints 146/1598 293/10654 3.5575657564998194e-46 1.6033580840500911e-44 7.683308984092168e-45 5718/1017/4172/6118/5689/80010/11130/9134/5684/5903/5720/83990/5682/9156/57060/5883/1763/7531/51512/1029/25946/1058/5700/7486/122706/7321/5707/991/10111/7532/10971/8697/5690/9212/51588/51720/5717/1027/5982/9491/23198/63967/79172/898/7533/2810/11200/143471/545/5706/472/5705/10197/7336/6232/7534/332/580/11073/7316/10213/5709/4174/891/5695/5501/116028/890/983/1026/84515/641/5714/51433/9861/4194/3796/5715/9656/5519/6119/5711/3364/7341/5701/10524/5688/4683/699/5687/144715/5685/5683/5698/5708/5692/5985/5686/5713/995/84126/5699/5710/1111/5702/7157/8900/5984/5719/64682/8924/5704/6233/5527/51434/5716/701/672/7514/5932/7158/7311/79184/5518/5347/7156/5983/6117/6396/7334/5694/7465/51230/5884/5810/5693/5721/5696/83695/5691/7529/7314/996/4193/5515/5516 146 Cottontail_rabbit_papillomavirus R-HSA-195253 Degradation of beta-catenin by the destruction complex 70/1598 82/10654 7.497111154950712e-46 3.2662414265068604e-44 1.5651863639283068e-44 8454/5718/5689/51176/8945/5684/5720/7090/1487/5682/1499/5700/122706/5707/1452/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/7091/5714/6934/9861/5715/5519/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/324/5699/8312/5710/5702/3065/7088/5719/5704/6233/5527/5716/7311/5518/7089/5694/5693/5721/5696/5691/7314/5515/5516 70 Cottontail_rabbit_papillomavirus R-HSA-5610780 Degradation of GLI1 by the proteasome 58/1598 60/10654 8.680602768732818e-46 3.6598541350754174e-44 1.753805992324627e-44 8454/5718/5689/8945/5684/5720/2735/5682/5700/122706/5707/5567/5690/5568/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/8650/5714/9861/5566/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/83737/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 58 Cottontail_rabbit_papillomavirus R-HSA-69206 G1/S Transition 91/1598 131/10654 1.964797352779933e-45 8.02496918776054e-44 3.845573766131777e-44 8454/5718/1017/4172/6118/5689/9134/1019/5684/5720/902/5682/7027/5700/5707/207/5690/5717/1027/9491/6500/898/5925/5706/5705/10197/91768/5934/7316/10213/5709/5422/1869/4174/891/5695/890/4331/983/1026/84515/5933/5714/5111/4609/9861/5715/5519/6119/5711/5928/5701/5688/5687/6502/5685/5683/5698/5708/10000/5692/5686/5713/1874/595/5699/5710/5702/3065/8900/5719/208/5704/6233/5716/7311/5518/6117/1719/5694/7465/1022/5693/5721/5696/7083/5691/7314/5515/6241/5516 91 Cottontail_rabbit_papillomavirus R-HSA-69242 S Phase 102/1598 161/10654 4.056386740188249e-45 1.6065749907351642e-43 7.698724435126024e-44 8454/5718/1017/4172/6118/5689/9134/1019/5684/5720/902/5682/1763/7027/5700/122706/7321/5707/207/8697/5690/5717/1027/5982/9491/23198/6500/898/5925/23244/143471/5706/5705/10197/91768/5934/7316/10213/5709/5422/9978/1869/4174/5695/890/4331/1026/84515/5714/5111/4609/51433/9861/5715/6119/5711/5928/2932/5701/5688/5687/6502/5685/5683/5698/5708/10000/5692/5985/5686/5713/1874/8243/9126/595/5699/5710/5702/8900/5984/5719/64682/208/5704/6233/51434/5716/51343/7311/5983/6117/5981/5694/10714/7465/1022/5693/5721/5696/5691/7314/996 102 Cottontail_rabbit_papillomavirus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 71/1598 86/10654 1.7963510983001996e-44 6.708088244223888e-43 3.2145230180108835e-43 8454/5718/1017/5689/8945/5684/5720/5682/5700/122706/7321/5707/991/8697/5690/9212/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/891/5695/890/983/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/8556/5719/64682/9232/5704/6233/51434/5716/701/51343/7311/5347/5694/5693/5721/5696/5691/7314/996 71 Cottontail_rabbit_papillomavirus R-HSA-453276 Regulation of mitotic cell cycle 71/1598 86/10654 1.7963510983001996e-44 6.708088244223888e-43 3.2145230180108835e-43 8454/5718/1017/5689/8945/5684/5720/5682/5700/122706/7321/5707/991/8697/5690/9212/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/891/5695/890/983/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/8556/5719/64682/9232/5704/6233/51434/5716/701/51343/7311/5347/5694/5693/5721/5696/5691/7314/996 71 Cottontail_rabbit_papillomavirus R-HSA-109581 Apoptosis 107/1598 178/10654 4.018471168180166e-44 1.4589282824476326e-42 6.991199839377775e-43 23368/4000/5718/5689/2934/27113/3837/596/5684/5720/1612/5682/1499/10018/7531/5747/1029/7027/842/5700/122706/5707/7532/207/10971/5690/5594/5717/9491/23198/63967/355/7533/2810/143471/5706/5705/841/10197/7534/9500/7316/10213/5709/1869/5695/6774/54205/4836/5366/5714/8797/3146/9861/5715/5711/5701/5688/5687/999/598/836/5685/5683/5698/5708/10000/5692/5686/5713/324/8837/5534/5699/5710/5702/7157/8626/5719/208/5704/6233/5580/5716/6093/1613/7311/7161/839/331/581/5599/7159/7431/5694/26060/637/317/8795/5693/5721/5696/5691/7529/7314/578/5595 107 Cottontail_rabbit_papillomavirus R-HSA-1169091 Activation of NF-kappaB in B cells 61/1598 67/10654 8.101967799006021e-44 2.861965381973208e-42 1.3714568536013038e-42 8454/1147/5718/5689/8945/5684/5720/4790/5579/5966/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/8517/7316/10213/5709/5695/5970/4792/4793/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/3551/5693/5721/5696/5691/7314 61 Cottontail_rabbit_papillomavirus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 57/1598 60/10654 9.890524724396907e-44 3.231728953696689e-42 1.5486479502674107e-42 8454/5718/1017/5689/9134/1019/5684/5720/5682/5700/5707/5690/5717/1027/9491/6500/898/5706/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/595/5699/5710/5702/8900/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 57 Cottontail_rabbit_papillomavirus R-HSA-5610783 Degradation of GLI2 by the proteasome 57/1598 60/10654 9.890524724396907e-44 3.231728953696689e-42 1.5486479502674107e-42 8454/5718/5689/8945/5684/5720/5682/5700/122706/5707/5567/1452/5690/5568/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5566/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 57 Cottontail_rabbit_papillomavirus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 57/1598 60/10654 9.890524724396907e-44 3.231728953696689e-42 1.5486479502674107e-42 8454/5718/5689/8945/5684/5720/5682/5700/122706/5707/5567/1452/5690/5568/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5566/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 57 Cottontail_rabbit_papillomavirus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 69/1598 83/10654 1.217469157652704e-43 3.88105411963923e-42 1.8598052600856457e-42 8454/1147/5718/5689/8945/5684/4893/4773/5720/4790/5579/5966/5682/4772/5700/122706/5707/5690/4775/5717/9491/23198/6500/143471/5706/5705/10197/8517/5530/7316/10213/5709/5695/5970/4792/4793/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5534/5699/5710/5702/5719/5704/6233/5716/7311/3845/5694/3265/3551/5693/5721/5696/5691/7314 69 Cottontail_rabbit_papillomavirus R-HSA-8939902 Regulation of RUNX2 expression and activity 64/1598 73/10654 1.515937751835498e-43 4.717453908688085e-42 2.2606089281757426e-42 8454/57154/5718/5689/7291/5684/5720/5682/5700/122706/5707/10273/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/11059/5714/6772/2099/9861/5715/5711/2932/5701/5688/5687/6502/650/2908/5685/5683/5698/5708/5692/5686/5713/55294/5699/5710/5702/5719/5704/6233/5716/7311/860/5694/5693/5721/5696/5691/10891/7314 64 Cottontail_rabbit_papillomavirus R-HSA-69541 Stabilization of p53 55/1598 57/10654 2.5405143704971076e-43 7.721982051720278e-42 3.7003820084352e-42 5718/5689/5684/5720/5682/1029/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/472/5705/10197/7316/10213/5709/5695/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/51230/5693/5721/5696/5691/7314/4193 55 Cottontail_rabbit_papillomavirus R-HSA-5357801 Programmed Cell Death 107/1598 181/10654 3.821070833622728e-43 1.1350317226238421e-41 5.439084081352926e-42 23368/4000/5718/5689/2934/27113/3837/596/5684/5720/1612/5682/1499/10018/7531/5747/1029/7027/842/5700/122706/5707/7532/207/10971/5690/5594/5717/9491/23198/63967/355/7533/2810/143471/5706/5705/841/10197/7534/9500/7316/10213/5709/1869/5695/6774/54205/4836/5366/5714/8797/3146/9861/5715/5711/5701/5688/5687/999/598/836/5685/5683/5698/5708/10000/5692/5686/5713/324/8837/5534/5699/5710/5702/7157/8626/5719/208/5704/6233/5580/5716/6093/1613/7311/7161/839/331/581/5599/7159/7431/5694/26060/637/317/8795/5693/5721/5696/5691/7529/7314/578/5595 107 Cottontail_rabbit_papillomavirus R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 53/1598 55/10654 1.1133447725654331e-41 3.1633513429196113e-40 1.5158813264906928e-40 8454/5718/5689/8945/5684/5720/5682/5700/122706/5707/991/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/51343/7311/5694/5693/5721/5696/5691/7314 53 Cottontail_rabbit_papillomavirus R-HSA-8941858 Regulation of RUNX3 expression and activity 53/1598 55/10654 1.1133447725654331e-41 3.1633513429196113e-40 1.5158813264906928e-40 57154/5718/5689/5684/5720/5682/1029/864/5700/5707/5690/5717/9491/5706/5705/10197/64750/7316/10213/5709/5695/5714/6714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/2033/5699/5710/5702/5719/5704/6233/5716/7311/7040/5694/5693/5721/5696/5691/7314/4193 53 Cottontail_rabbit_papillomavirus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 102/1598 171/10654 1.1745276212211002e-41 3.266186384970166e-40 1.565159987965408e-40 6158/5718/5689/6138/6144/6203/5684/9349/4736/5720/6194/6191/6128/5682/51121/6132/6147/6129/6217/5700/122706/5707/6230/6222/6152/5690/6136/6125/5717/9491/23198/6154/51065/6141/26986/143471/6202/5706/5705/10197/6232/6160/7316/6155/10213/5709/6175/9978/6218/5695/6209/5714/6231/6229/9861/6130/5715/6142/5711/6204/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/140801/6156/5699/6143/5710/6181/6124/5702/6207/5719/5704/6233/5716/7311/6223/6188/6189/6135/6201/5694/9045/6187/6168/5693/6208/5721/6137/5696/5691/4440/6122/7314 102 Cottontail_rabbit_papillomavirus R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 51/1598 52/10654 2.1381534638173593e-41 5.822013702519352e-40 2.7899151556388794e-40 5718/5689/1019/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/595/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Cottontail_rabbit_papillomavirus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 66/1598 80/10654 2.2902910574016706e-41 6.109000840865272e-40 2.9274396974307068e-40 8454/5718/1017/5689/8945/5684/5720/5682/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/891/5695/890/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/5719/64682/5704/6233/51434/5716/701/51343/7311/5347/5694/5693/5721/5696/5691/7314/996 66 Cottontail_rabbit_papillomavirus R-HSA-4641258 Degradation of DVL 54/1598 57/10654 2.740052413474057e-41 7.1624970088211855e-40 3.4322761810885566e-40 5718/5689/5684/5720/5682/5700/122706/5707/1856/5690/5717/9491/23198/143471/5706/5705/10197/8452/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/1855/5716/1857/23072/7311/5694/5693/5721/5696/5691/7314 54 Cottontail_rabbit_papillomavirus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 88/1598 134/10654 6.794279635477449e-41 1.7412006830527502e-39 8.343852183919675e-40 8454/1147/5718/5689/3725/8945/5684/5601/4893/4773/5290/5720/2205/4790/5682/4772/5700/122706/7321/5707/5336/5690/5594/4775/5717/4214/9491/23198/6500/143471/5706/5705/2206/10197/8517/5530/7316/10213/5709/5695/5970/4792/6850/5714/9861/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5602/5692/5686/5713/5534/5699/5710/10454/5702/695/5719/7189/5609/5704/6233/5716/7409/2353/7311/3845/5599/7334/5694/3265/3551/5693/5721/5696/2207/5691/7314/5595 88 Cottontail_rabbit_papillomavirus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 52/1598 54/10654 7.356865431729225e-41 1.814230777220773e-39 8.69381317155688e-40 8454/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/6790/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 52 Cottontail_rabbit_papillomavirus R-HSA-9604323 Negative regulation of NOTCH4 signaling 52/1598 54/10654 7.356865431729225e-41 1.814230777220773e-39 8.69381317155688e-40 8454/5718/5689/5684/5720/5682/5700/5707/207/5690/5717/9491/6500/5706/5705/10197/7534/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/4855/55294/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 52 Cottontail_rabbit_papillomavirus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 53/1598 56/10654 1.780946584212203e-40 4.3105503436395355e-39 2.06562030722468e-39 5718/3303/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/3315/23198/26986/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/3304/3312/5693/5721/5696/5691/7314 53 Cottontail_rabbit_papillomavirus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 69/1598 88/10654 1.9014977538804256e-40 4.518650116948575e-39 2.1653419398255567e-39 5718/3303/5689/5684/5720/5682/5700/122706/5707/3842/207/5690/5578/5717/9491/3315/23198/26986/143471/5706/5705/10197/7534/7538/7316/10213/5709/5695/5714/9861/5715/5711/1432/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5580/5716/7514/7311/11340/5600/5694/3304/3312/8570/6418/23016/5693/54512/5721/5696/5691/7529/7314/1994 69 Cottontail_rabbit_papillomavirus R-HSA-2871837 FCERI mediated NF-kB activation 66/1598 82/10654 4.659072319376861e-40 1.0873942002545638e-38 5.210804567724121e-39 8454/1147/5718/5689/8945/5684/5720/2205/4790/5682/5700/122706/7321/5707/5690/5717/9491/23198/6500/143471/5706/5705/2206/10197/8517/7316/10213/5709/5695/5970/4792/5714/9861/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/10454/5702/5719/7189/5704/6233/5716/7311/7334/5694/3551/5693/5721/5696/2207/5691/7314 66 Cottontail_rabbit_papillomavirus R-HSA-8878171 Transcriptional regulation by RUNX1 122/1598 239/10654 5.183296897347103e-40 1.1885208850583621e-38 5.695404716383244e-39 55904/1912/5718/9070/5689/27161/25/5684/4773/5720/902/2624/11091/5579/6597/5682/6929/1459/5700/122706/5707/8535/6045/5690/2625/57690/5717/5929/9491/23198/27327/80012/1460/143471/6938/5706/6598/5705/10197/6599/192670/86/7316/10213/5709/5695/28996/5079/10398/1457/4331/1911/6603/5714/23309/6714/2099/9861/5715/8850/5711/5701/5688/1387/84733/5687/3558/5685/5683/8289/5698/5708/5692/5686/5713/2033/1021/6605/6602/57332/595/50943/5699/4602/8312/5710/5702/192669/3065/83737/861/5719/5371/23112/5704/6233/5716/7311/6688/7161/860/58508/25942/9739/4343/648/3276/5694/6601/23466/26523/7057/1022/5693/5721/23429/4297/5696/5691/55193/7314/6015 122 Cottontail_rabbit_papillomavirus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 55/1598 60/10654 5.472036607428953e-40 1.23309514584649e-38 5.909005047949595e-39 8454/1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5970/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 55 Cottontail_rabbit_papillomavirus R-HSA-5607764 CLEC7A (Dectin-1) signaling 74/1598 101/10654 1.0284451891822782e-39 2.2782675631546399e-038 1.0917482382934086e-38 8454/1147/5718/5689/8945/5684/4773/5720/4790/5682/4772/5700/122706/7321/5707/5336/5690/3553/4775/5717/9491/23198/6500/143471/5706/5705/841/10197/8517/5530/7316/10213/5709/5695/5970/4792/6850/5714/6714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5534/5699/5710/10454/5702/9040/5719/7189/5704/6233/5580/5716/7311/7334/5694/3551/5693/5721/5696/5691/7314 74 Cottontail_rabbit_papillomavirus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 47/1598 47/10654 1.0530820774407908e-39 2.2939637920251894e-38 1.0992698878548606e-38 8454/8841/7090/79718/79885/2648/9734/892/55869/23462/51564/55534/3280/6500/84441/3091/10013/10046/7316/83933/9978/9611/7091/9759/9612/1024/4609/10014/22938/8850/1387/6907/26508/2033/55294/3066/3065/7088/9794/6233/23493/7311/7089/388585/3516/4851/7314 47 Cottontail_rabbit_papillomavirus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 61/1598 72/10654 1.1355266196966011e-39 2.433005396628619e-38 1.165898772596165e-38 5718/5689/5684/5720/5682/5700/122706/7321/5707/991/8697/5690/9212/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/64682/9232/5704/6233/51434/5716/51343/7311/5347/5694/5693/5721/5696/5691/7314/996 61 Cottontail_rabbit_papillomavirus R-HSA-376176 Signaling by ROBO receptors 115/1598 218/10654 1.4225651690826875e-39 2.9988591548243105e-38 1.43705649508353e-38 6158/5718/5689/6138/6144/25/55740/6203/5684/9349/4736/7852/5720/6194/6191/6128/5682/51121/6132/6147/10298/6129/6217/5700/122706/5707/5567/6230/6222/6152/5690/6136/5578/5568/6125/5717/9491/23198/6154/51065/6141/26986/143471/6202/5706/5705/10197/6232/6160/7316/6155/10213/5709/6175/9978/6218/5695/6209/5714/6714/6231/6229/9861/5566/6130/5715/6142/5711/6204/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/7408/140801/6156/5699/6143/5710/6181/6124/5702/998/6207/5719/5704/6233/5716/7311/6223/387/6188/6189/6135/6201/5694/9045/6187/6168/5693/6208/5721/6137/5696/5691/4440/6122/7314/6387 115 Cottontail_rabbit_papillomavirus R-HSA-180534 Vpu mediated degradation of CD4 50/1598 52/10654 3.200247253176387e-39 6.242870387912742e-38 2.9915901266927737e-38 5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Cottontail_rabbit_papillomavirus R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/1598 52/10654 3.200247253176387e-39 6.242870387912742e-38 2.9915901266927737e-38 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/472/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Cottontail_rabbit_papillomavirus R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 50/1598 52/10654 3.200247253176387e-39 6.242870387912742e-38 2.9915901266927737e-38 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Cottontail_rabbit_papillomavirus R-HSA-69610 p53-Independent DNA Damage Response 50/1598 52/10654 3.200247253176387e-39 6.242870387912742e-38 2.9915901266927737e-38 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Cottontail_rabbit_papillomavirus R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 50/1598 52/10654 3.200247253176387e-39 6.242870387912742e-38 2.9915901266927737e-38 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Cottontail_rabbit_papillomavirus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 54/1598 59/10654 3.4430212534290346e-39 6.61768937975257e-38 3.171203786053058e-38 8454/1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 54 Cottontail_rabbit_papillomavirus R-HSA-449147 Signaling by Interleukins 181/1598 461/10654 6.622046820753922e-39 1.254350028221069e-37 6.010858670249556e-38 8454/7124/1147/5718/2308/834/5689/3725/7291/8945/596/5684/5601/351/5290/5720/4790/6627/6597/5606/2309/5682/5604/5700/6351/122706/7184/5707/27250/3589/207/5451/7422/5690/3553/2625/5594/8878/4582/5717/9491/23198/6500/5908/5743/3091/143471/4318/5706/3726/4312/3383/5705/301/6097/10197/8517/6657/6778/3576/7534/3313/332/6776/3688/4313/7316/3565/10213/5709/6175/9978/5695/79155/84868/3185/6774/1435/5970/4792/5443/6850/1026/4793/5714/6772/8651/4609/3146/9861/5566/5715/5519/5711/4988/5598/3552/1432/5701/867/5688/79923/5687/6950/3558/4067/3717/23291/4088/598/2247/836/5685/5683/5698/5708/3320/5602/5692/5686/5713/595/6195/5699/57162/5710/3181/10454/5702/2002/998/7157/6648/5719/7189/6285/5609/5704/6233/1398/5716/7409/1385/2353/604/6196/7311/53832/2939/6347/3932/5518/302/1386/7040/6935/6197/5599/5600/7431/4282/6777/7334/5694/3312/3551/3569/3162/57161/4170/5693/5721/5696/3586/5691/51231/4692/7314/5595/5515/5516 181 Cottontail_rabbit_papillomavirus R-HSA-8948751 Regulation of PTEN stability and activity 59/1598 69/10654 7.061218918175302e-39 1.3184304465793027e-37 6.317932716262112e-38 5718/5689/5684/5720/5682/1459/5700/122706/5707/10273/207/5690/5717/9491/23198/1460/143471/5706/5705/10197/7316/10213/5709/5695/1457/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/10000/5692/5686/5713/5728/5699/5710/5702/5719/5987/208/5704/6233/5716/7311/331/5694/5693/5721/5696/23608/5691/7314 59 Cottontail_rabbit_papillomavirus R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 52/1598 56/10654 1.386567406720342e-38 2.5524557754697003e-37 1.22313952112469e-37 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/84447/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/6400/5710/5702/5719/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 52 Cottontail_rabbit_papillomavirus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 62/1598 76/10654 2.361112743851662e-38 4.2860754947418374e-37 2.0538919336136534e-37 5718/5689/5684/5720/5682/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/891/5695/890/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/5719/64682/9232/5704/6233/51434/5716/701/7311/5347/5694/5693/5721/5696/5691/7314/996 62 Cottontail_rabbit_papillomavirus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 60/1598 72/10654 3.4062287003421463e-38 6.098549193626281e-37 2.9224312569626204e-37 5718/1017/5689/9134/5684/5720/5682/5700/122706/7321/5707/8697/5690/5717/9491/23198/898/143471/5706/5705/10197/7316/10213/5709/5695/890/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/5719/64682/5704/6233/51434/5716/51343/7311/5694/5693/5721/5696/5691/7314/996 60 Cottontail_rabbit_papillomavirus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 62/1598 77/10654 1.0389446665619614e-37 1.835000917833086e-36 8.793343906178761e-37 5718/5689/5684/5720/5682/51512/5700/122706/5707/51807/5690/5717/9491/23198/7277/143471/5706/5705/10197/7316/10213/5709/891/5695/983/1026/5714/9861/5715/5711/5701/5688/5687/7846/5685/5683/5698/5708/3320/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/3326/5716/7311/10383/5347/84790/5694/5693/5721/5696/7280/5691/7314 62 Cottontail_rabbit_papillomavirus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 61/1598 75/10654 1.3266291521433683e-37 2.3118724024685096e-36 1.1078517130179706e-36 5718/5689/5684/5720/5682/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/891/5695/890/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/5719/64682/9232/5704/6233/51434/5716/701/7311/5694/5693/5721/5696/5691/7314/996 61 Cottontail_rabbit_papillomavirus R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 48/1598 50/10654 1.384886525649516e-37 2.381640380294628e-36 1.14128460216269e-36 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 48 Cottontail_rabbit_papillomavirus R-HSA-9020702 Interleukin-1 signaling 73/1598 103/10654 1.4339636106254132e-37 2.434013557256383e-36 1.1663818842407668e-36 8454/1147/5718/5689/8945/5684/351/5720/4790/5682/5604/5700/122706/5707/5690/3553/8878/5717/9491/23198/6500/143471/5706/5705/10197/8517/7316/10213/5709/9978/5695/79155/5970/4792/4793/5714/3146/9861/5715/5711/3552/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/57162/5710/10454/5702/5719/7189/6285/5704/6233/5716/7311/7334/5694/3551/57161/5693/5721/5696/5691/7314 73 Cottontail_rabbit_papillomavirus R-HSA-69239 Synthesis of DNA 79/1598 119/10654 2.543497031871693e-37 4.2619879752003884e-36 2.0423491686419128e-36 8454/5718/1017/4172/6118/5689/9134/5684/5720/5682/1763/5700/122706/7321/5707/8697/5690/5717/5982/9491/23198/6500/898/143471/5706/5705/10197/7316/10213/5709/5422/9978/4174/5695/890/84515/5714/5111/51433/9861/5715/6119/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5985/5686/5713/5699/5710/5702/8900/5984/5719/64682/5704/6233/51434/5716/51343/7311/5983/6117/5981/5694/10714/5693/5721/5696/5691/7314/996 79 Cottontail_rabbit_papillomavirus R-HSA-453274 Mitotic G2-G2/M phases 106/1598 198/10654 2.699218066861707e-37 4.4656683713775335e-36 2.139953031022939e-36 10844/8454/115106/5718/1017/5689/8945/22995/5684/5720/902/2305/5682/22981/7531/51512/4659/5700/122706/5707/203068/51807/7532/1454/22974/5690/5717/9491/23198/6500/7277/143471/5706/5705/10197/7316/10213/5709/9978/1869/891/5695/890/4331/983/1026/6790/5714/1871/9861/5566/5715/5519/5711/5928/5701/5688/5687/23291/7846/5685/7283/5683/5698/5708/3320/5692/5686/5713/80097/2033/995/5699/5710/5702/10540/5520/7157/8900/5719/5704/6233/3326/5716/7514/7311/54930/5518/10383/55835/5347/84790/9662/5694/1453/7465/1022/8481/5693/5721/5696/7280/5691/7314/5515/5516 106 Cottontail_rabbit_papillomavirus R-HSA-69052 Switching of origins to a post-replicative state 67/1598 90/10654 8.674495652247027e-37 1.417195727185858e-35 6.791216990903923e-36 8454/5718/1017/4172/5689/9134/5684/5720/5682/5700/122706/7321/5707/8697/5690/5717/9491/23198/6500/898/143471/5706/5705/10197/7316/10213/5709/9978/4174/5695/890/84515/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/5719/64682/5704/6233/51434/5716/51343/7311/5694/5693/5721/5696/5691/7314/996 67 Cottontail_rabbit_papillomavirus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 47/1598 49/10654 9.091792089516337e-37 1.467033612468871e-35 7.030040667007436e-36 1017/9134/1820/57060/7027/25946/7832/4849/1027/4869/898/4850/2810/9337/5934/1869/891/890/10769/983/1026/6790/5933/5111/25904/246175/1647/4848/23019/28984/2033/995/1874/7157/8900/10498/55571/55835/5325/581/57472/3276/144455/85456/79733/29883/1263 47 Cottontail_rabbit_papillomavirus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 59/1598 72/10654 9.271185800320845e-37 1.4777365659779688e-35 7.081329334006294e-36 5718/5689/5684/5720/5682/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/890/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/5719/64682/5704/6233/51434/5716/701/7311/5694/5693/5721/5696/5691/7314/996 59 Cottontail_rabbit_papillomavirus R-HSA-69306 DNA Replication 81/1598 127/10654 2.5988679566432993e-36 4.0924342401599906e-35 1.961098838557721e-35 8454/5718/1017/4172/6118/5689/9134/5684/5720/5682/1763/5700/122706/7321/5707/8697/5690/5717/5982/9491/23198/6500/898/143471/5706/5705/10197/7316/10213/5709/5422/9978/1869/4174/5695/890/84515/5714/5111/1871/51433/9861/5715/6119/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5985/5686/5713/5699/5710/5702/8900/5984/5719/64682/5704/6233/51434/5716/51343/7311/5983/6117/5981/5694/10714/5693/5721/5696/5691/7314/996 81 Cottontail_rabbit_papillomavirus R-HSA-1234174 Cellular response to hypoxia 60/1598 75/10654 3.183082968777674e-36 4.952725524038595e-35 2.3733513363693184e-35 5718/5689/5684/5720/5682/112399/5700/122706/7321/5707/7422/5690/5717/9491/23198/3091/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/10370/5701/5688/1387/5687/5685/5683/5698/5708/5692/5686/5713/2033/5699/5710/7428/5702/5719/5704/6233/5716/7311/55662/5694/405/5693/5721/5696/5691/768/7314 60 Cottontail_rabbit_papillomavirus R-HSA-69275 G2/M Transition 104/1598 196/10654 3.788924493944093e-36 5.826028604217564e-35 2.791839100800911e-35 10844/8454/115106/5718/1017/5689/8945/22995/5684/5720/902/2305/5682/22981/7531/51512/4659/5700/122706/5707/203068/51807/7532/1454/22974/5690/5717/9491/23198/6500/7277/143471/5706/5705/10197/7316/10213/5709/9978/891/5695/890/4331/983/1026/6790/5714/9861/5566/5715/5519/5711/5928/5701/5688/5687/23291/7846/5685/7283/5683/5698/5708/3320/5692/5686/5713/80097/2033/995/5699/5710/5702/10540/5520/7157/8900/5719/5704/6233/3326/5716/7514/7311/54930/5518/10383/55835/5347/84790/9662/5694/1453/7465/1022/8481/5693/5721/5696/7280/5691/7314/5515/5516 104 Cottontail_rabbit_papillomavirus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 59/1598 73/10654 4.143352180307621e-36 6.296931743793093e-35 3.017496385903347e-35 5718/5689/5684/5720/5682/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/890/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/5719/64682/5704/6233/51434/5716/701/7311/5694/5693/5721/5696/5691/7314/996 59 Cottontail_rabbit_papillomavirus R-HSA-68949 Orc1 removal from chromatin 58/1598 71/10654 5.224364029289195e-36 7.845113365994951e-35 3.759386665136711e-35 8454/5718/1017/4172/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/4174/5695/890/84515/5714/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 58 Cottontail_rabbit_papillomavirus R-HSA-4641257 Degradation of AXIN 50/1598 55/10654 5.282096221939983e-36 7.845113365994951e-35 3.759386665136711e-35 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/64750/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/8312/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Cottontail_rabbit_papillomavirus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 56/1598 67/10654 7.42783605250613e-36 1.090806934901743e-34 5.227158428434236e-35 5718/5689/5684/5720/5682/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/64682/9232/5704/6233/51434/5716/7311/5694/5693/5721/5696/5691/7314/996 56 Cottontail_rabbit_papillomavirus R-HSA-5387390 Hh mutants abrogate ligand secretion 52/1598 59/10654 8.103589617862758e-36 1.1768212922829582e-34 5.639340143424962e-35 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/84447/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/6400/5710/5702/5719/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 52 Cottontail_rabbit_papillomavirus R-HSA-180585 Vif-mediated degradation of APOBEC3G 49/1598 54/10654 3.287152885884312e-35 4.721218485550325e-34 2.2624129174102554e-34 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 49 Cottontail_rabbit_papillomavirus R-HSA-5658442 Regulation of RAS by GAPs 56/1598 68/10654 3.6071678685627573e-35 5.1245308741429605e-34 2.455680642785859e-34 5718/5689/5684/4893/5720/5682/153090/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/8452/7316/10213/5709/9978/5695/84078/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/3845/5694/3265/4763/5693/5721/5696/5691/7314 56 Cottontail_rabbit_papillomavirus R-HSA-5688426 Deubiquitination 132/1598 297/10654 5.11837004024045e-35 7.166808859253607e-34 3.4343424243997074e-34 9960/5718/23358/5689/5684/8295/5720/3607/10617/221937/5682/2648/79594/5700/10474/122706/7321/5707/991/8237/4738/5690/55611/2625/4303/51720/5717/9491/57646/23198/63967/409/4086/1080/3091/143471/5706/5705/4287/27005/10197/7706/8517/86/64750/580/7316/10213/5709/5695/79155/890/25862/4792/983/84132/5714/4092/8678/2099/9100/1643/79589/4609/7415/9861/4194/4089/5715/8850/7128/5711/5701/5688/5687/7046/6502/9099/4088/5685/5683/5698/5708/9146/5692/5686/5713/324/2033/408/5728/5699/8312/5710/10454/5702/219333/7157/8900/9958/4087/5719/7189/57599/5704/6233/5716/672/7311/55593/367/6881/79184/51616/78990/387/60/7040/7345/3054/1540/5694/7874/5693/10254/5721/5696/5691/5886/7314/4193/7528 132 Cottontail_rabbit_papillomavirus R-HSA-5621481 C-type lectin receptors (CLRs) 85/1598 142/10654 5.154399638636871e-35 7.166808859253607e-34 3.4343424243997074e-34 8454/1147/5718/5689/8945/5684/4893/4773/5720/4790/5682/4772/5700/122706/7321/5707/5567/5336/5690/3553/5568/4775/4582/5717/9491/23198/6500/143471/5706/5705/841/10197/8517/5530/7316/10213/5709/5695/5970/4792/6850/5714/6714/9861/5566/5715/5711/5701/5688/1387/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/2033/5534/5699/5710/10454/5702/9040/5719/7189/5704/6233/5580/5716/7311/3845/7334/5694/3265/3551/5693/5721/5696/2207/5691/7314 85 Cottontail_rabbit_papillomavirus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 74/1598 112/10654 8.277227541232291e-35 1.1387722522516427e-33 5.457008739094974e-34 8454/1147/5718/5689/8945/5684/4893/4773/5720/4790/5579/5966/5682/4772/5700/122706/5707/5336/5690/4775/5717/9491/23198/6500/143471/5706/5705/10197/8517/5530/7316/10213/5709/5695/5970/4792/6850/4793/5714/9861/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/5534/5699/5710/5702/695/5719/5704/6233/5716/7409/7311/3845/5694/3265/3551/5693/5721/5696/5691/7314 74 Cottontail_rabbit_papillomavirus R-HSA-169911 Regulation of Apoptosis 48/1598 53/10654 2.040776377191438e-34 2.7784320051970932e-33 1.33142757064573e-33 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 48 Cottontail_rabbit_papillomavirus R-HSA-4086400 PCP/CE pathway 65/1598 92/10654 1.960733653481494e-33 2.6419369949487755e-32 1.2660190166266835e-32 57154/5718/5689/5684/5720/5579/5682/5700/122706/5707/1856/5690/1212/5578/5717/9491/5582/23198/409/143471/5706/7471/5705/10197/64750/7316/10213/5709/5695/54361/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/1855/7474/5716/1857/7311/1213/387/1211/5694/5693/5721/5696/6259/5691/7314 65 Cottontail_rabbit_papillomavirus R-HSA-5358346 Hedgehog ligand biogenesis 53/1598 65/10654 6.447743938611172e-33 8.59918502833143e-32 4.12073860738308e-32 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/84447/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/6400/5710/5702/5719/6868/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 53 Cottontail_rabbit_papillomavirus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 52/1598 63/10654 7.88622610819104e-33 1.0411411639803727e-31 4.989159526181466e-32 5718/5689/5684/5720/5682/5700/7321/5707/8697/5690/5717/9491/5706/5705/10197/7316/10213/5709/5695/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/64682/5704/6233/51434/5716/51343/7311/5694/5693/5721/5696/5691/7314/996 52 Cottontail_rabbit_papillomavirus R-HSA-5678895 Defective CFTR causes cystic fibrosis 51/1598 61/10654 9.234734258129881e-33 1.2069797675375754e-31 5.783859877460293e-32 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/6400/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Cottontail_rabbit_papillomavirus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 53/1598 66/10654 2.805040247575419e-32 3.6298887164169034e-31 1.7394465318471854e-31 5718/5689/5684/5720/5682/112399/5700/122706/7321/5707/5690/5717/9491/23198/3091/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/7428/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 53 Cottontail_rabbit_papillomavirus R-HSA-4608870 Asymmetric localization of PCP proteins 52/1598 64/10654 3.6040312017498646e-32 4.618106647732425e-31 2.213001615109566e-31 57154/5718/5689/5684/5720/5682/5700/122706/5707/1856/5690/5717/9491/23198/143471/5706/5705/10197/64750/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/7474/5716/7311/5694/5693/5721/5696/5691/7314 52 Cottontail_rabbit_papillomavirus R-HSA-5632684 Hedgehog 'on' state 61/1598 85/10654 4.5295931720083007e-32 5.747745898849368e-31 2.7543259451660083e-31 57154/5718/5689/5684/5720/2735/5682/5700/122706/5707/11127/22873/1452/5690/5717/9491/23198/409/143471/5706/5705/10197/64750/8452/7316/10213/5709/9978/5695/8650/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/408/5699/5710/5702/83737/5719/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 61 Cottontail_rabbit_papillomavirus R-HSA-3858494 Beta-catenin independent WNT signaling 83/1598 146/10654 6.31696892653673e-32 7.938729218253371e-31 3.8042474810620995e-31 57154/5718/5689/27161/51176/5684/5720/5579/5682/1499/51701/4772/5700/122706/5707/1856/5690/1212/5578/57690/5717/9491/5582/23198/27327/409/143471/5706/7471/5705/10197/192670/64750/5530/7316/10213/5709/5695/54361/5714/6934/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5534/5699/2783/5710/5702/192669/5719/23112/5704/6233/1855/7474/5716/1857/7311/1213/387/1211/4343/3845/5694/26523/5693/5721/2791/5696/6259/5691/7314 83 Cottontail_rabbit_papillomavirus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 94/1598 182/10654 1.6130143441886301e-31 2.007818807480514e-30 9.621489070598847e-31 1912/7020/7150/6670/5903/7068/1487/5241/3622/9631/5468/7021/1029/7486/1788/9112/8535/51564/1786/6045/9212/51588/4869/3090/80012/7153/6613/8517/332/10210/4929/28996/1655/5970/4792/3190/6996/9759/9612/8856/1911/6790/641/6672/5111/2099/4927/9656/7341/1387/84733/10521/1616/2908/2033/23512/8243/9126/57332/7022/142/7428/3066/3065/7157/1107/7329/5987/5371/8924/672/115426/7158/10155/367/10499/6612/9063/7155/25942/6117/6294/6396/648/11315/8648/7421/4286/8480/10891/7508/6015/4193/8554 94 Cottontail_rabbit_papillomavirus R-HSA-162906 HIV Infection 109/1598 233/10654 1.9216754045663145e-31 2.369462031856767e-30 1.1354487246444461e-30 6884/5718/6875/5689/8945/2963/3837/5434/5684/5903/7852/5720/902/5682/9631/3159/5700/122706/5707/5430/6874/5690/5045/7520/6878/5717/4869/9491/23198/6500/6749/143471/5706/5705/10197/7316/10213/5709/9978/5695/6872/292/4331/4836/9397/5714/4927/8148/9861/6879/5715/2962/5711/23327/5701/5688/54457/8812/5687/83860/5685/5683/5698/5708/5692/2965/5686/128866/5713/5699/5710/2068/5702/2071/6873/5719/5704/6233/2968/5716/7514/1025/7311/6881/3932/51616/6880/6908/7251/11198/6396/6883/5694/1104/51497/2547/6882/2961/138474/1022/5693/5721/5696/8178/5691/8480/6877/7314/25920 109 Cottontail_rabbit_papillomavirus R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 49/1598 59/10654 3.0159738128458577e-31 3.683997919055641e-30 1.7653757192752438e-30 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/84515/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 49 Cottontail_rabbit_papillomavirus R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 45/1598 51/10654 3.503180712630005e-31 4.239497399451311e-30 2.03157166083319e-30 5718/5689/5684/1728/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/5694/5693/5721/5696/5691 45 Cottontail_rabbit_papillomavirus R-HSA-68867 Assembly of the pre-replicative complex 53/1598 68/10654 4.468464868952183e-31 5.358058333688535e-30 2.567587249663495e-30 5718/4172/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/1869/4174/5695/84515/5714/1871/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 53 Cottontail_rabbit_papillomavirus R-HSA-2990846 SUMOylation 95/1598 188/10654 7.400296412807056e-31 8.792897646853475e-30 4.2135659001150226e-30 1912/7020/7150/6670/5903/7068/29843/1487/5241/3622/9631/5468/7021/1029/7486/1788/9112/8535/51564/1786/6045/9212/51588/4869/3090/80012/7153/6613/8517/332/10210/4929/28996/1655/5970/4792/3190/6996/9759/9612/8856/1911/6790/641/6672/5111/2099/4927/9656/7341/1387/84733/10521/1616/2908/2033/23512/8243/9126/57332/7022/142/7428/3066/3065/7157/1107/7329/5987/5371/8924/672/115426/7158/10155/367/10499/6612/9063/7155/25942/6117/6294/6396/648/11315/8648/7421/4286/8480/10891/7508/6015/4193/8554 95 Cottontail_rabbit_papillomavirus R-HSA-195721 Signaling by WNT 134/1598 331/10654 2.0140648157336005e-30 2.3715159587061403e-29 1.1364329685741986e-29 8454/57154/5718/27123/9070/5689/27161/51176/8945/5684/8295/857/5720/7472/6662/7015/7090/1487/5579/6597/5682/1499/51701/864/1459/4772/5700/122706/5707/1856/207/1454/1452/5690/1212/5578/57690/5717/5929/9491/5582/23198/6500/27327/409/1460/143471/5706/7471/5705/10197/6657/192670/7534/64750/8452/5530/7316/10213/5709/9978/5695/7091/54361/89780/1457/5714/6934/4609/9861/5715/5519/5711/2932/5701/10524/5688/1387/5687/1455/5685/5683/5698/5708/5692/5686/5713/324/2033/54894/5534/5699/2783/8312/5710/5702/192669/3065/7088/5719/23112/208/57680/5704/6233/5527/1855/7474/5716/1857/7514/23072/7311/5518/1213/387/1211/7089/331/4343/3845/6659/5694/26523/5693/5721/2791/5696/6259/5691/7314/4221/5515/5516 134 Cottontail_rabbit_papillomavirus R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 44/1598 50/10654 2.1103236643547577e-30 2.462672347599704e-29 1.1801152070404897e-29 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/5694/5693/5721/5696/5691 44 Cottontail_rabbit_papillomavirus R-HSA-9614085 FOXO-mediated transcription 51/1598 65/10654 3.366962722837132e-30 3.894354228980648e-29 1.866178686621419e-29 2308/27113/857/2290/2309/57060/10018/4802/7532/207/10971/4303/23410/1027/7295/2810/4287/181/6720/1649/7534/5934/4800/5443/1026/901/4089/8850/1647/9314/10370/1387/4088/2908/10628/10000/6794/2033/4852/4801/3630/3066/3065/6648/4087/208/604/23411/25942/7529/10891 51 Cottontail_rabbit_papillomavirus R-HSA-201681 TCF dependent signaling in response to WNT 107/1598 233/10654 5.200995471021353e-30 5.962895684758692e-29 2.8574259512998196e-29 5718/27123/9070/5689/51176/8945/5684/8295/857/5720/6662/7015/7090/1487/6597/5682/1499/864/1459/5700/122706/5707/1856/207/1454/1452/5690/5717/5929/9491/23198/1460/143471/5706/7471/5705/10197/6657/7534/64750/8452/7316/10213/5709/9978/5695/7091/54361/89780/1457/5714/6934/4609/9861/5715/5519/5711/2932/5701/10524/5688/1387/5687/1455/5685/5683/5698/5708/5692/5686/5713/324/2033/54894/5699/8312/5710/5702/3065/7088/5719/208/57680/5704/6233/5527/1855/7474/5716/1857/7514/23072/7311/5518/7089/331/6659/5694/5693/5721/5696/6259/5691/7314/4221/5515/5516 107 Cottontail_rabbit_papillomavirus R-HSA-2559583 Cellular Senescence 96/1598 195/10654 5.2604799697969925e-30 5.978649843934495e-29 2.864975361125136e-29 1912/1017/3725/9134/1019/5601/4790/5606/3159/7290/1029/7027/7321/2146/10111/8535/6045/8697/57690/5594/1027/27327/80012/898/5931/7295/5925/1051/472/79813/192670/3576/3490/8550/29855/7316/2114/1869/890/6774/5970/1026/1911/6667/1871/51433/4194/1031/5598/3552/5928/1432/10524/84733/4683/5602/23512/1021/57332/6195/25842/192669/7157/8900/23135/64682/8091/23112/5609/6233/51434/2353/1030/51343/6196/7311/3397/57634/4343/8726/6197/5599/648/5600/23466/26523/3456/2113/3569/10919/7314/23523/996/6015/5595/4193 96 Cottontail_rabbit_papillomavirus R-HSA-202424 Downstream TCR signaling 64/1598 98/10654 8.349566314656445e-30 9.407657907979288e-29 4.5081596707990793e-29 8454/1147/5718/5689/8945/5684/5290/5720/4790/5682/5700/122706/7321/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/8517/7316/10213/5709/5695/5970/4792/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5728/5699/5710/5702/5719/7189/5704/6233/5716/7311/3932/7334/5694/3551/5693/5721/5696/5691/7314 64 Cottontail_rabbit_papillomavirus R-HSA-5689880 Ub-specific processing proteases 103/1598 220/10654 8.593725966597165e-30 9.599999861831191e-29 4.6003301395639346e-29 9960/5718/23358/5689/5684/8295/5720/5682/2648/79594/5700/10474/122706/5707/991/8237/5690/55611/2625/4303/5717/9491/57646/23198/63967/409/4086/1080/3091/143471/5706/5705/27005/10197/8517/64750/7316/10213/5709/5695/890/25862/4792/84132/5714/4092/8678/9100/1643/79589/4609/9861/4194/4089/5715/5711/5701/5688/5687/7046/6502/9099/4088/5685/5683/5698/5708/9146/5692/5686/5713/408/5728/5699/8312/5710/10454/5702/219333/7157/8900/9958/4087/5719/7189/57599/5704/6233/5716/7311/367/6881/51616/1540/5694/7874/5693/10254/5721/5696/5691/7314/4193 103 Cottontail_rabbit_papillomavirus R-HSA-9012852 Signaling by NOTCH3 43/1598 49/10654 1.2672077614224672e-29 1.4035936815077667e-28 6.726035843410954e-29 23129/142678/2648/23462/4904/55534/3280/182/84441/23385/10046/7316/1950/4854/3714/54492/102/6772/5664/10320/22938/8850/1387/2173/26508/2033/9148/9794/83464/6233/23493/7311/57534/1956/54567/388585/55851/51107/3516/4851/5663/28514/7314 43 Cottontail_rabbit_papillomavirus R-HSA-446652 Interleukin-1 family signaling 78/1598 140/10654 2.977078154917532e-29 3.269782477711945e-28 1.5668832394302802e-28 8454/1147/5718/834/5689/8945/5684/351/5720/4790/5682/5604/5700/122706/5707/5690/3553/8878/5717/9491/23198/6500/143471/5706/5705/10197/8517/7316/3565/10213/5709/9978/5695/79155/6774/5970/4792/4793/5714/3146/9861/5715/5711/3552/5701/5688/5687/23291/4088/5685/5683/5698/5708/5692/5686/5713/5699/57162/5710/10454/5702/5719/7189/6285/5704/6233/5716/7311/5599/7334/5694/3551/57161/5693/5721/5696/5691/7314 78 Cottontail_rabbit_papillomavirus R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 40/1598 44/10654 5.30757699521438e-29 5.780835943954329e-28 2.770182729958383e-28 23368/834/27113/79370/9540/8793/55240/58484/3486/355/55367/472/8794/332/64065/5366/124446/8797/84883/147923/5876/1387/51499/843/94241/7157/8626/604/63970/7161/839/581/7159/637/317/10397/8795/665/5875/27166 40 Cottontail_rabbit_papillomavirus R-HSA-73894 DNA Repair 132/1598 334/10654 9.689818871228648e-29 1.0466606003880864e-27 5.015608724124441e-28 9318/8467/1017/6118/2176/80010/25/3838/5434/4436/83990/902/5888/9156/2074/5883/322/1763/328/27339/7486/5430/10111/4913/7320/51588/7520/51720/675/2956/7515/5982/63967/5531/51548/4292/11200/545/472/6613/7706/7336/86/580/11073/5591/8450/7316/9978/11201/116028/890/6996/4331/641/5111/9100/1643/7415/5395/64421/9656/6119/51455/3364/7341/10524/4683/144715/1161/1642/2965/5985/25898/2033/84126/142/7398/2068/1111/10987/2071/7157/8900/5984/4595/7329/4255/79728/8924/57599/6233/2067/51426/2873/2968/672/5932/7158/7311/2189/4968/79184/6612/55247/60/7156/5983/6117/2175/5599/7334/10973/5981/10714/7874/2547/5884/5810/1022/8178/2188/83695/5886/55183/7508/7314/51514/51138/8451/8554/7528 132 Cottontail_rabbit_papillomavirus R-HSA-69002 DNA Replication Pre-Initiation 58/1598 85/10654 1.1409433957169974e-28 1.2223057526246848e-27 5.857302160928503e-28 5718/1017/4172/6118/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5422/1869/4174/5695/84515/5714/1871/9861/5715/6119/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/6117/5694/5693/5721/5696/5691/7314 58 Cottontail_rabbit_papillomavirus R-HSA-5610787 Hedgehog 'off' state 68/1598 113/10654 2.0263405476804155e-28 2.153192760827889e-27 1.0318122600512172e-27 8454/5718/5689/8945/5684/5720/2735/5682/5700/122706/5707/5567/11127/1452/5690/5568/5717/9491/23198/6500/7277/143471/5706/5705/10197/7316/10213/5709/9978/5695/8650/5714/9861/5566/5715/5711/2932/5701/5688/5687/7846/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/83737/5719/5704/6233/5716/7311/10383/23322/84790/5694/8481/5693/5721/5696/7280/5691/7314 68 Cottontail_rabbit_papillomavirus R-HSA-5683057 MAPK family signaling cascades 120/1598 294/10654 1.076687504489986e-27 1.1348633615874289e-26 5.438277293476586e-27 5718/2308/5689/27161/3725/5684/4893/5720/2309/5682/1844/5604/2904/5747/153090/5700/10642/3815/122706/5707/5567/10048/5690/57690/5594/5568/5717/9491/3315/23198/27327/409/5908/143471/5706/2064/5705/10197/3337/192670/8550/8452/7316/10213/5709/9978/1950/5695/2263/4233/983/5597/84078/5714/6714/4609/9861/5566/5715/5519/5711/2261/5701/5688/5159/5687/3558/3717/2247/5685/5683/5698/5708/5692/5686/5713/408/5699/1445/5710/2264/8555/5702/192669/998/2066/8556/5719/23112/5704/6233/5527/5716/7514/7311/8826/5518/1956/60/1843/4343/3845/5694/3265/26523/369/4763/8202/3569/5693/5721/5696/5691/5245/7529/5156/7314/5595/5515/5516 120 Cottontail_rabbit_papillomavirus R-HSA-5358351 Signaling by Hedgehog 79/1598 149/10654 1.1822091523825662e-27 1.2361178897312112e-26 5.923490068780017e-27 8454/57154/5718/5689/8945/5684/5720/2735/5682/5700/122706/5707/5567/11127/22873/1452/5690/5568/5717/9491/23198/6500/409/7277/143471/5706/5705/10197/64750/8452/84447/7316/10213/5709/9978/5695/8650/5714/7415/9861/5566/5715/5711/2932/5701/5688/5687/7846/5685/5683/5698/5708/5692/5686/5713/408/5699/6400/5710/5702/83737/5719/6868/5704/6233/5716/7311/10383/6469/23322/84790/5694/8481/5693/5721/5696/7280/5691/7314 79 Cottontail_rabbit_papillomavirus R-HSA-8943724 Regulation of PTEN gene transcription 47/1598 61/10654 2.7242409995188068e-27 2.825859512992921e-26 1.3541548828017462e-26 1912/3725/6591/8841/5468/1822/23186/2146/5978/9112/9219/8535/51564/6045/5594/84232/80012/5931/1911/1108/57167/2122/7101/10014/1958/5928/84733/57459/54815/23512/57332/6615/3066/3065/7157/1107/23028/10542/2475/57504/1386/8726/648/23466/53615/6015/5595 47 Cottontail_rabbit_papillomavirus R-HSA-351202 Metabolism of polyamines 46/1598 59/10654 3.906462292387991e-27 4.020272611142601e-26 1.926518909217451e-26 5718/5689/5684/1728/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/6303/5694/5693/5721/5696/5691 46 Cottontail_rabbit_papillomavirus R-HSA-2122948 Activated NOTCH1 Transmits Signal to the Nucleus 31/1598 31/10654 2.2375519791078714e-26 2.284750341167178e-25 1.094854792408868e-25 142678/113878/23220/182/409/23385/7316/3714/8650/54492/1272/102/5664/8788/9148/408/83737/92737/6868/83464/6233/7311/1840/57534/54567/55851/51107/4851/5663/28514/7314 31 Cottontail_rabbit_papillomavirus R-HSA-72689 Formation of a pool of free 40S subunits 61/1598 101/10654 9.764760913402821e-26 9.893443809160842e-25 4.740948791085009e-25 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/8666/6129/6217/6230/6222/6152/6136/8668/8667/6125/6154/51065/8662/6141/10480/6202/6232/6160/6155/6175/6218/6209/6231/6229/6130/6142/6204/140801/6156/6143/6181/6124/6207/6233/7311/6223/3646/51386/6188/6189/8665/6135/6201/9045/6187/6168/6208/6137/6122 61 Cottontail_rabbit_papillomavirus R-HSA-202403 TCR signaling 67/1598 119/10654 1.19744215380338e-25 1.2038899192469366e-24 5.769053291603329e-25 8454/1147/5718/5689/8945/55740/5684/5290/5720/4790/5682/5700/122706/7321/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/8517/7316/10213/5709/5695/5970/4792/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/7408/5728/5699/1445/5710/5702/5719/7189/5704/6233/5716/7311/3932/7334/5694/3551/5693/5721/5696/5691/7314 67 Cottontail_rabbit_papillomavirus R-HSA-5689603 UCH proteinases 61/1598 102/10654 2.081873784453457e-25 2.077106134565396e-24 9.953514678584226e-25 5718/5689/5684/5720/3607/221937/5682/5700/122706/5707/4738/5690/5717/9491/23198/143471/5706/5705/10197/86/580/7316/10213/5709/5695/5714/4092/9861/5715/5711/5701/5688/5687/7046/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9958/5719/5704/6233/5716/7311/60/7040/7345/3054/5694/5693/5721/5696/5691/7314/7528 61 Cottontail_rabbit_papillomavirus R-HSA-5685938 HDR through Single Strand Annealing (SSA) 34/1598 37/10654 3.5059773103392184e-25 3.471448745919211e-24 1.663521929546918e-24 6118/80010/25/83990/5888/9156/5883/1763/7486/10111/5982/545/472/580/11073/116028/641/6119/3364/10524/4683/144715/5985/84126/5984/2067/672/5932/7156/5983/6117/5884/5810/83695 34 Cottontail_rabbit_papillomavirus R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 63/1598 111/10654 1.888935258663637e-24 1.8562694609574234e-23 8.895262990936795e-24 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/8666/6129/6217/6230/6222/6152/6136/8668/8667/6125/6154/51065/8662/6141/10480/26986/6202/6232/6160/6155/6175/6218/6209/6231/6229/6130/6142/6204/8894/140801/6156/6143/6181/6124/6207/6233/7311/6223/3646/51386/6188/6189/8665/6135/6201/9045/6187/6168/6208/6137/6122 63 Cottontail_rabbit_papillomavirus R-HSA-5619084 ABC transporter disorders 51/1598 77/10654 2.00608145397697e-24 1.956677955483507e-23 9.376421564150017e-24 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/6400/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Cottontail_rabbit_papillomavirus R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 63/1598 112/10654 3.700205154448443e-24 3.582346768047492e-23 1.716664379646646e-23 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/8666/6129/6217/6230/6222/6152/6136/8668/8667/6125/6154/51065/8662/6141/10480/6202/6232/6160/6155/6175/6218/9669/6209/6231/6229/6130/6142/6204/8894/140801/6156/6143/6181/6124/6207/6233/7311/6223/3646/51386/6188/6189/8665/6135/6201/9045/6187/6168/6208/6137/6122 63 Cottontail_rabbit_papillomavirus R-HSA-156902 Peptide chain elongation 55/1598 89/10654 5.011884133648922e-24 4.816568060793486e-23 2.3081045352330563e-23 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/1938/6147/6129/1915/6217/6230/6222/6152/6136/6125/6154/51065/6141/6202/6232/6160/6155/6175/6218/6209/6231/6229/6130/6142/6204/140801/6156/6143/6181/6124/6207/6233/7311/6223/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122 55 Cottontail_rabbit_papillomavirus R-HSA-72613 Eukaryotic Translation Initiation 65/1598 119/10654 6.4541996834641925e-24 6.112781874121522e-23 2.9292515725867233e-23 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/8666/6129/6217/6230/6222/6152/6136/8668/8667/6125/6154/51065/8662/6141/10480/26986/6202/6232/6160/6155/6175/6218/9669/6209/6231/6229/6130/8890/6142/6204/8894/140801/6156/6143/6181/6124/6207/6233/7311/6223/3646/51386/6188/6189/8665/6135/6201/9045/6187/6168/6208/6137/6122 65 Cottontail_rabbit_papillomavirus R-HSA-72737 Cap-dependent Translation Initiation 65/1598 119/10654 6.4541996834641925e-24 6.112781874121522e-23 2.9292515725867233e-23 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/8666/6129/6217/6230/6222/6152/6136/8668/8667/6125/6154/51065/8662/6141/10480/26986/6202/6232/6160/6155/6175/6218/9669/6209/6231/6229/6130/8890/6142/6204/8894/140801/6156/6143/6181/6124/6207/6233/7311/6223/3646/51386/6188/6189/8665/6135/6201/9045/6187/6168/6208/6137/6122 65 Cottontail_rabbit_papillomavirus R-HSA-350054 Notch-HLH transcription pathway 28/1598 28/10654 6.948503664533124e-24 6.533593014061002e-23 3.1309047182106845e-23 8841/79718/79885/2648/9734/55869/51564/55534/84441/10013/10046/83933/4854/9611/9759/9612/10014/22938/8850/1387/6907/4855/4853/3066/3065/9794/3516/4851 28 Cottontail_rabbit_papillomavirus R-HSA-68882 Mitotic Anaphase 89/1598 201/10654 9.875111620430038e-24 9.219122062787185e-23 4.41781309335028e-23 4000/5718/5689/11130/5684/5903/5720/5682/55869/1058/5700/122706/7321/5707/991/51807/8697/5690/9212/5717/9491/23198/79172/23244/7277/143471/5706/5705/10197/6232/332/7443/7316/10213/5709/5695/5501/5714/51433/9861/3796/5715/5519/5711/5701/5688/699/5687/7846/5685/5683/7444/5698/5708/5692/5686/5713/8243/9126/5699/5710/5702/5520/5719/64682/9232/5704/6233/5527/51434/5716/701/7514/7311/5518/10383/5347/84790/6396/5694/5693/5721/5696/7280/5691/7314/996/5515/5516 89 Cottontail_rabbit_papillomavirus R-HSA-156842 Eukaryotic Translation Elongation 56/1598 93/10654 1.2335140257474948e-23 1.1434062635829614e-22 5.479214970658899e-23 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/1938/6147/6129/1915/6217/1936/6230/6222/6152/6136/6125/6154/51065/6141/6202/6232/6160/6155/6175/6218/6209/6231/6229/6130/6142/6204/140801/6156/6143/6181/6124/6207/6233/7311/6223/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122 56 Cottontail_rabbit_papillomavirus R-HSA-2555396 Mitotic Metaphase and Anaphase 89/1598 202/10654 1.5140445986546582e-23 1.3904407196748958e-22 6.663006710478501e-23 4000/5718/5689/11130/5684/5903/5720/5682/55869/1058/5700/122706/7321/5707/991/51807/8697/5690/9212/5717/9491/23198/79172/23244/7277/143471/5706/5705/10197/6232/332/7443/7316/10213/5709/5695/5501/5714/51433/9861/3796/5715/5519/5711/5701/5688/699/5687/7846/5685/5683/7444/5698/5708/5692/5686/5713/8243/9126/5699/5710/5702/5520/5719/64682/9232/5704/6233/5527/51434/5716/701/7514/7311/5518/10383/5347/84790/6396/5694/5693/5721/5696/7280/5691/7314/996/5515/5516 89 Cottontail_rabbit_papillomavirus R-HSA-3247509 Chromatin modifying enzymes 108/1598 274/10654 1.5319316268797627e-23 1.3904407196748958e-22 6.663006710478501e-23 55904/84678/23774/9070/10196/1019/8295/8841/8464/29943/55167/11091/4790/9869/79718/64769/84148/7862/6597/2648/23186/55869/10474/2146/5978/1788/9112/9219/51147/6839/6871/5929/23569/5931/6598/117143/79813/6599/86/7403/8819/83933/9611/2874/84289/5970/11143/9612/29072/6603/1108/2122/27097/84444/8850/5928/10524/1387/27154/56950/57459/3717/6907/8289/54815/2033/23512/6605/6602/595/7994/3066/3065/1107/79084/23028/23135/55693/10498/23133/22992/57504/80854/6881/58508/10499/57634/1386/6880/10419/60/9739/8726/3054/10902/6883/3276/6601/51230/6187/53615/9913/8648/64754/4297/55193/8089/10919 108 Cottontail_rabbit_papillomavirus R-HSA-4839726 Chromatin organization 108/1598 274/10654 1.5319316268797627e-23 1.3904407196748958e-22 6.663006710478501e-23 55904/84678/23774/9070/10196/1019/8295/8841/8464/29943/55167/11091/4790/9869/79718/64769/84148/7862/6597/2648/23186/55869/10474/2146/5978/1788/9112/9219/51147/6839/6871/5929/23569/5931/6598/117143/79813/6599/86/7403/8819/83933/9611/2874/84289/5970/11143/9612/29072/6603/1108/2122/27097/84444/8850/5928/10524/1387/27154/56950/57459/3717/6907/8289/54815/2033/23512/6605/6602/595/7994/3066/3065/1107/79084/23028/23135/55693/10498/23133/22992/57504/80854/6881/58508/10499/57634/1386/6880/10419/60/9739/8726/3054/10902/6883/3276/6601/51230/6187/53615/9913/8648/64754/4297/55193/8089/10919 108 Cottontail_rabbit_papillomavirus R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 34/1598 39/10654 1.9078767526339585e-23 1.7197206315121265e-22 8.240919548582253e-23 6118/80010/83990/5888/9156/5883/1763/7486/10111/675/5982/545/472/580/11073/116028/641/6119/3364/10524/4683/144715/5985/84126/1111/5984/672/5932/7156/5983/6117/5884/5810/83695 34 Cottontail_rabbit_papillomavirus R-HSA-1236974 ER-Phagosome pathway 52/1598 83/10654 3.466769570318147e-23 3.1034711153464506e-22 1.4871866577788733e-22 1147/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/8517/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/695/5719/5704/6233/5716/7311/5694/3551/5693/5721/5696/5691/7314 52 Cottontail_rabbit_papillomavirus R-HSA-2467813 Separation of Sister Chromatids 85/1598 190/10654 4.389544078164987e-23 3.902812319837849e-22 1.8702318127519995e-22 5718/5689/11130/5684/5903/5720/5682/55869/1058/5700/122706/7321/5707/991/51807/8697/5690/9212/5717/9491/23198/79172/23244/7277/143471/5706/5705/10197/6232/332/7316/10213/5709/5695/5501/5714/51433/9861/3796/5715/5519/5711/5701/5688/699/5687/7846/5685/5683/5698/5708/5692/5686/5713/8243/9126/5699/5710/5702/5719/64682/9232/5704/6233/5527/51434/5716/701/7514/7311/5518/10383/5347/84790/6396/5694/5693/5721/5696/7280/5691/7314/996/5515/5516 85 Cottontail_rabbit_papillomavirus R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 35/1598 42/10654 9.665550640135803e-23 8.535726139633442e-22 4.0903290404557634e-22 6118/80010/83990/5888/9156/5883/1763/7486/10111/675/5982/545/472/580/11073/116028/641/6119/3364/10524/4683/144715/5985/84126/1111/5984/79728/672/5932/7156/5983/6117/5884/5810/83695 35 Cottontail_rabbit_papillomavirus R-HSA-168254 Influenza Infection 74/1598 155/10654 2.423431697162663e-22 2.125788743752752e-21 1.0186802259355597e-21 6158/3303/6138/6144/2963/3837/3838/6203/5434/5903/9349/4736/6194/6191/6128/51121/6132/9631/6147/6129/6217/3843/5430/6230/6222/6152/6136/6125/6154/51065/6141/6202/6232/6160/6155/6175/6218/6209/4927/6231/6229/6130/2962/6142/3840/6204/3320/140801/6156/6143/6181/6124/6207/6233/7514/7311/6223/1213/5610/1211/6188/6189/7040/6396/6135/6201/3304/9045/6187/6168/6208/6137/8480/6122 74 Cottontail_rabbit_papillomavirus R-HSA-192823 Viral mRNA Translation 53/1598 89/10654 4.0771607653144795e-22 3.5525660801773495e-21 1.702393442359379e-21 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/6152/6136/6125/6154/51065/6141/6202/6232/6160/6155/6175/6218/6209/6231/6229/6130/6142/6204/140801/6156/6143/6181/6124/6207/6233/7311/6223/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122 53 Cottontail_rabbit_papillomavirus R-HSA-1980145 Signaling by NOTCH2 30/1598 33/10654 5.2096608063995895e-22 4.509289188055803e-21 2.1608561727485225e-21 142678/55534/3280/182/84441/23385/10046/7316/3714/54492/1272/102/5664/2033/9148/4853/9794/83464/6233/1385/7311/57534/54567/388585/55851/51107/3516/5663/28514/7314 30 Cottontail_rabbit_papillomavirus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 57/1598 102/10654 8.762803776989785e-22 7.534858247714241e-21 3.6107120826239074e-21 8454/8792/7124/1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/8600/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 57 Cottontail_rabbit_papillomavirus R-HSA-168255 Influenza Life Cycle 70/1598 144/10654 9.079359386564672e-22 7.756027920418318e-21 3.716696824909515e-21 6158/3303/6138/6144/2963/3837/6203/5434/5903/9349/4736/6194/6191/6128/51121/6132/9631/6147/6129/6217/3843/5430/6230/6222/6152/6136/6125/6154/51065/6141/6202/6232/6160/6155/6175/6218/6209/4927/6231/6229/6130/2962/6142/6204/3320/140801/6156/6143/6181/6124/6207/6233/7514/7311/6223/1213/1211/6188/6189/6396/6135/6201/3304/9045/6187/6168/6208/6137/8480/6122 70 Cottontail_rabbit_papillomavirus R-HSA-69231 Cyclin D associated events in G1 35/1598 44/10654 1.865178404039948e-21 1.5704125859394686e-20 7.525433806901978e-21 8454/25/1019/902/1029/7027/1027/6500/5925/5934/7316/1869/4331/1026/5933/6714/1871/1031/5519/4067/3717/6502/1021/1874/595/5520/6233/1030/7311/5518/1022/1028/7314/5515/5516 35 Cottontail_rabbit_papillomavirus R-HSA-69236 G1 Phase 35/1598 44/10654 1.865178404039948e-21 1.5704125859394686e-20 7.525433806901978e-21 8454/25/1019/902/1029/7027/1027/6500/5925/5934/7316/1869/4331/1026/5933/6714/1871/1031/5519/4067/3717/6502/1021/1874/595/5520/6233/1030/7311/5518/1022/1028/7314/5515/5516 35 Cottontail_rabbit_papillomavirus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 113/1598 309/10654 1.8744021683745763e-21 1.5704125859394686e-20 7.525433806901978e-21 8454/57154/5718/197131/23352/5689/8945/5684/5720/142678/55070/5682/7319/5700/122706/7321/5707/991/10273/8697/7320/5690/5717/9491/23198/6500/10533/143471/5706/5705/26259/10197/7336/26263/64750/8452/7316/10213/5709/9978/5695/80196/4008/11059/84078/7337/5714/26272/7704/8651/3093/51433/9861/25831/5715/5711/23327/5701/5688/5687/6502/23291/5685/10616/5683/5698/5708/5692/5686/5713/25898/55294/5699/79654/5710/7428/5702/22954/83737/9040/5719/10075/64682/80176/8924/51191/5704/6233/56658/51434/5716/10425/51343/7311/868/80204/57520/7334/5930/5694/23014/7332/5693/5721/5696/23608/55585/5691/51132/9820/7314/996/140691 113 Cottontail_rabbit_papillomavirus R-HSA-69473 G2/M DNA damage checkpoint 54/1598 95/10654 3.539611185089875e-21 2.928020138552194e-20 1.4031103631768658e-20 6118/80010/83990/9156/5883/1763/7531/7486/10111/7532/10971/51588/51720/5982/7533/2810/11200/545/472/7336/7534/580/11073/891/116028/983/641/9656/6119/3364/7341/10524/4683/144715/5985/995/84126/1111/7157/5984/8924/672/5932/7158/79184/7156/5983/6117/7334/7465/5884/5810/83695/7529 54 Cottontail_rabbit_papillomavirus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 54/1598 95/10654 3.539611185089875e-21 2.928020138552194e-20 1.4031103631768658e-20 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/6152/6136/6125/6154/51065/6141/26986/6202/6232/6160/6155/6175/6218/6209/6231/6229/6130/6142/6204/140801/6156/6143/6181/6124/6207/6233/7311/6223/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122 54 Cottontail_rabbit_papillomavirus R-HSA-2408557 Selenocysteine synthesis 53/1598 93/10654 7.020005405700326e-21 5.734466915781454e-20 2.7479626423629566e-20 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/6152/6136/6125/6154/51065/6141/6202/6232/6160/6155/6175/6218/6209/6231/6229/6130/6142/6204/140801/6156/6143/6181/6124/6207/6233/7311/6223/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122 53 Cottontail_rabbit_papillomavirus R-HSA-72764 Eukaryotic Translation Termination 53/1598 93/10654 7.020005405700326e-21 5.734466915781454e-20 2.7479626423629566e-20 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/6152/6136/6125/6154/51065/6141/6202/6232/6160/6155/6175/6218/6209/6231/6229/6130/6142/6204/140801/6156/6143/6181/6124/6207/6233/7311/6223/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122 53 Cottontail_rabbit_papillomavirus R-HSA-3899300 SUMOylation of transcription cofactors 35/1598 45/10654 7.192677296412342e-21 5.839024364230392e-20 2.79806668281487e-20 1912/1487/3622/8535/6045/51588/4869/80012/6613/10210/28996/1655/9612/1911/7341/1387/84733/10521/1616/2033/57332/7329/115426/10155/10499/6612/9063/25942/6294/648/11315/8648/10891/6015/8554 35 Cottontail_rabbit_papillomavirus R-HSA-5693532 DNA Double-Strand Break Repair 75/1598 166/10654 8.076569691030516e-21 6.51609665813388e-20 3.122520445850005e-20 8467/1017/6118/80010/25/3838/83990/5888/9156/5883/322/1763/7486/10111/51588/7520/51720/675/7515/5982/63967/5531/51548/11200/545/472/6613/7336/580/11073/5591/7316/116028/890/641/5111/64421/9656/6119/3364/7341/10524/4683/144715/5985/84126/142/1111/7157/8900/5984/7329/79728/8924/6233/2067/51426/672/5932/7158/7311/79184/7156/5983/6117/5599/7334/5981/10714/2547/5884/5810/83695/55183/7314 75 Cottontail_rabbit_papillomavirus R-HSA-170834 Signaling by TGF-beta Receptor Complex 46/1598 73/10654 8.270522985650895e-21 6.631640209966699e-20 3.177889038722817e-20 57154/5590/892/7027/7321/6497/10273/4738/5045/3726/64750/7316/9611/5501/9612/1024/6667/5933/4092/4609/4089/22938/23327/867/8812/7046/4088/1874/142/3065/6498/9958/9040/4087/5499/6233/7514/1025/1030/7311/25937/387/7040/7314/4221/5054 46 Cottontail_rabbit_papillomavirus R-HSA-8951664 Neddylation 93/1598 234/10654 1.0480779286551412e-20 8.352669833855302e-20 4.002608264119442e-20 8454/9318/5718/5689/8945/5684/5720/11091/23363/5682/23038/5700/122706/7321/5707/4738/5690/5717/5929/9491/23198/6500/5931/3091/143471/5706/5705/26259/10197/332/26263/8452/8450/7316/10213/5709/9978/5695/4008/84078/5714/26272/7704/1643/9861/5715/5711/5701/5688/5687/1161/6502/23291/5685/5683/55832/5698/5708/1642/5692/5686/23113/5713/55294/5699/10238/5710/10987/7428/5702/9040/5719/80176/5704/6233/2873/5716/7311/83987/80204/51667/5694/23014/5693/5721/5696/5691/9820/7314/51514/10537/51138/8451 93 Cottontail_rabbit_papillomavirus R-HSA-162909 Host Interactions of HIV factors 64/1598 129/10654 1.3211075601223084e-20 1.04647732186658e-19 5.0147304515009467e-20 5718/5689/8945/3837/5684/5903/5720/5682/9631/3159/5700/122706/5707/5690/5717/4869/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/292/5714/4927/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7514/1025/7311/3932/6396/5694/1104/5693/5721/5696/5691/8480/7314 64 Cottontail_rabbit_papillomavirus R-HSA-6806003 Regulation of TP53 Expression and Degradation 31/1598 37/10654 2.062643472562146e-20 1.6200747364638754e-19 7.76341536017401e-20 1017/1029/207/11200/472/117584/639/7316/890/80196/983/4194/5519/1616/9099/10000/900/7157/8900/208/6233/5527/2475/7311/5518/7874/51230/7314/4193/5515/5516 31 Cottontail_rabbit_papillomavirus R-HSA-109606 Intrinsic Pathway for Apoptosis 38/1598 53/10654 2.0700266334312714e-20 1.6200747364638754e-19 7.76341536017401e-20 23368/27113/596/10018/7531/1029/7027/842/7532/207/10971/5594/7533/2810/841/7534/1869/6774/54205/4836/5366/598/836/10000/5534/7157/8626/208/7161/331/581/5599/7159/637/317/7529/578/5595 38 Cottontail_rabbit_papillomavirus R-HSA-2559585 Oncogene Induced Senescence 29/1598 33/10654 2.2689866699293994e-20 1.7652176057129316e-19 8.458941532631534e-20 1019/1029/7027/57690/5594/27327/5925/192670/7316/2114/1869/6667/1871/4194/1031/1021/192669/7157/23112/6233/1030/7311/3397/4343/26523/2113/7314/5595/4193 29 Cottontail_rabbit_papillomavirus R-HSA-927802 Nonsense-Mediated Decay (NMD) 59/1598 115/10654 5.0828501642890076e-20 3.907814802779843e-19 1.8726290078959503e-19 6158/9887/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/6152/6136/6125/6154/51065/6141/26986/6202/6232/6160/6155/6175/6218/6209/6231/6229/6130/6142/6204/140801/6156/6143/6181/6124/5520/6207/6233/23381/7311/6223/5518/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/5515 59 Cottontail_rabbit_papillomavirus R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 59/1598 115/10654 5.0828501642890076e-20 3.907814802779843e-19 1.8726290078959503e-19 6158/9887/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/6152/6136/6125/6154/51065/6141/26986/6202/6232/6160/6155/6175/6218/6209/6231/6229/6130/6142/6204/140801/6156/6143/6181/6124/5520/6207/6233/23381/7311/6223/5518/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/5515 59 Cottontail_rabbit_papillomavirus R-HSA-5685942 HDR through Homologous Recombination (HRR) 43/1598 67/10654 5.457642533610384e-20 4.1714261938179953e-19 1.998951866727103e-19 6118/80010/83990/5888/9156/5883/1763/7486/10111/675/5982/545/472/580/11073/7316/116028/641/5111/6119/3364/10524/4683/144715/5985/84126/1111/5984/79728/6233/51426/672/5932/7311/7156/5983/6117/5981/10714/5884/5810/83695/7314 43 Cottontail_rabbit_papillomavirus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 49/1598 85/10654 1.0745779732071166e-19 8.071686270009778e-19 3.8679606416106135e-19 8454/1147/3725/8945/5601/351/4790/5606/5604/5594/4214/6500/8517/7316/79155/5970/4792/4793/3146/5519/5598/1432/23291/5602/6195/57162/10454/2002/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 49 Cottontail_rabbit_papillomavirus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 49/1598 85/10654 1.0745779732071166e-19 8.071686270009778e-19 3.8679606416106135e-19 8454/1147/3725/8945/5601/351/4790/5606/5604/5594/4214/6500/8517/7316/79155/5970/4792/4793/3146/5519/5598/1432/23291/5602/6195/57162/10454/2002/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 49 Cottontail_rabbit_papillomavirus R-HSA-975871 MyD88 cascade initiated on plasma membrane 49/1598 85/10654 1.0745779732071166e-19 8.071686270009778e-19 3.8679606416106135e-19 8454/1147/3725/8945/5601/351/4790/5606/5604/5594/4214/6500/8517/7316/79155/5970/4792/4793/3146/5519/5598/1432/23291/5602/6195/57162/10454/2002/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 49 Cottontail_rabbit_papillomavirus R-HSA-6804757 Regulation of TP53 Degradation 30/1598 36/10654 1.171531382268267e-19 8.749665809283572e-19 4.192849157591693e-19 1017/1029/207/11200/472/117584/7316/890/80196/983/4194/5519/1616/9099/10000/900/7157/8900/208/6233/5527/2475/7311/5518/7874/51230/7314/4193/5515/5516 30 Cottontail_rabbit_papillomavirus R-HSA-168273 Influenza Viral RNA Transcription and Replication 64/1598 134/10654 1.684075315548498e-19 1.2506172939897084e-18 5.992971368130122e-19 6158/6138/6144/2963/6203/5434/5903/9349/4736/6194/6191/6128/51121/6132/9631/6147/6129/6217/3843/5430/6230/6222/6152/6136/6125/6154/51065/6141/6202/6232/6160/6155/6175/6218/6209/4927/6231/6229/6130/2962/6142/6204/3320/140801/6156/6143/6181/6124/6207/6233/7311/6223/6188/6189/6396/6135/6201/9045/6187/6168/6208/6137/8480/6122 64 Cottontail_rabbit_papillomavirus R-HSA-5693607 Processing of DNA double-strand break ends 53/1598 98/10654 1.8016882993901742e-19 1.3303992131655127e-18 6.37528717298337e-19 1017/6118/80010/83990/9156/5883/1763/7486/10111/51588/51720/5982/63967/5531/51548/545/472/6613/7336/580/11073/7316/116028/890/641/9656/6119/3364/7341/10524/4683/144715/5985/84126/1111/8900/5984/7329/8924/6233/672/5932/7158/7311/79184/7156/5983/6117/7334/5884/5810/83695/7314 53 Cottontail_rabbit_papillomavirus R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs 62/1598 130/10654 6.855353525491717e-19 5.03367812236948e-18 2.4121439075503088e-18 5718/5689/25/5684/5720/902/2624/5682/6929/5700/122706/5707/5690/2625/5717/9491/23198/143471/6938/5706/5705/10197/7316/10213/5709/5695/4331/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/4602/5710/5702/83737/861/5719/5704/6233/5716/7311/6688/7161/5694/1022/5693/5721/4297/5696/5691/7314 62 Cottontail_rabbit_papillomavirus R-HSA-5684996 MAPK1/MAPK3 signaling 95/1598 255/10654 7.816113549264645e-19 5.707072854127872e-18 2.7348353788958918e-18 5718/5689/5684/4893/5720/5682/1844/5604/2904/5747/153090/5700/3815/122706/5707/10048/5690/5594/5717/9491/23198/409/5908/143471/5706/2064/5705/10197/8452/7316/10213/5709/9978/1950/5695/2263/4233/983/84078/5714/6714/9861/5715/5519/5711/2261/5701/5688/5159/5687/3558/3717/2247/5685/5683/5698/5708/5692/5686/5713/408/5699/1445/5710/2264/5702/2066/5719/5704/6233/5527/5716/7311/8826/5518/1956/60/1843/3845/5694/3265/369/4763/3569/5693/5721/5696/5691/5245/7529/5156/7314/5595/5515/5516 95 Cottontail_rabbit_papillomavirus R-HSA-8939211 ESR-mediated signaling 87/1598 223/10654 7.917955924430333e-19 5.749315774016914e-18 2.755078231015233e-18 3727/27161/3725/2354/2963/3838/596/5434/5590/4893/857/5290/7090/5241/2309/5747/5430/207/5451/2625/57690/5594/6722/1027/3315/27327/4318/5481/192670/2100/4313/1950/5469/1655/6667/6714/2099/4609/2962/7391/8850/10524/1387/10000/3320/2033/8243/4846/9126/595/2783/4602/8312/192669/3065/2002/2066/861/23028/23112/208/10498/3326/7514/1385/1025/2353/10499/1386/6908/1956/3169/4343/3845/3276/7392/3265/26523/8202/8648/3480/2791/2288/10728/5595/7528/6387 87 Cottontail_rabbit_papillomavirus R-HSA-5693538 Homology Directed Repair 64/1598 138/10654 1.1414195452450753e-18 8.242184230029356e-18 3.9496634453086355e-18 1017/6118/80010/25/83990/5888/9156/5883/1763/7486/10111/51588/51720/675/7515/5982/63967/5531/51548/545/472/6613/7336/580/11073/7316/116028/890/641/5111/9656/6119/3364/7341/10524/4683/144715/5985/84126/142/1111/8900/5984/7329/79728/8924/6233/2067/51426/672/5932/7158/7311/79184/7156/5983/6117/7334/5981/10714/5884/5810/83695/7314 64 Cottontail_rabbit_papillomavirus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 51/1598 95/10654 1.3405902392062706e-18 9.574598047227299e-18 4.588157563001042e-18 8454/1147/3725/8945/5601/351/4790/5606/5604/5594/4214/6500/8517/7316/79155/5970/4792/4793/8651/3146/5519/5598/1432/23291/5602/6195/57162/10454/2002/695/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 51 Cottontail_rabbit_papillomavirus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 51/1598 95/10654 1.3405902392062706e-18 9.574598047227299e-18 4.588157563001042e-18 8454/1147/3725/8945/5601/351/4790/5606/5604/5594/4214/6500/8517/7316/79155/5970/4792/4793/8651/3146/5519/5598/1432/23291/5602/6195/57162/10454/2002/695/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 51 Cottontail_rabbit_papillomavirus R-HSA-5673001 RAF/MAP kinase cascade 93/1598 249/10654 1.5156348984951023e-18 1.0765950067027711e-17 5.15905471741754e-18 5718/5689/5684/4893/5720/5682/1844/5604/2904/5747/153090/5700/3815/122706/5707/10048/5690/5594/5717/9491/23198/409/5908/143471/5706/2064/5705/10197/8452/7316/10213/5709/9978/1950/5695/2263/4233/84078/5714/6714/9861/5715/5519/5711/2261/5701/5688/5159/5687/3558/3717/2247/5685/5683/5698/5708/5692/5686/5713/408/5699/1445/5710/2264/5702/2066/5719/5704/6233/5527/5716/7311/8826/5518/1956/60/1843/3845/5694/3265/369/4763/5693/5721/5696/5691/5245/7529/5156/7314/5595/5515/5516 93 Cottontail_rabbit_papillomavirus R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 62/1598 132/10654 1.8020491828580222e-18 1.2731233956732082e-17 6.100820846660161e-18 1017/6118/80010/25/83990/5888/9156/5883/1763/7486/10111/51588/51720/675/5982/63967/5531/51548/545/472/6613/7336/580/11073/7316/116028/890/641/5111/9656/6119/3364/7341/10524/4683/144715/5985/84126/1111/8900/5984/7329/79728/8924/6233/2067/51426/672/5932/7158/7311/79184/7156/5983/6117/7334/5981/10714/5884/5810/83695/7314 62 Cottontail_rabbit_papillomavirus R-HSA-1236975 Antigen processing-Cross presentation 52/1598 99/10654 2.198835888866236e-18 1.5450959713699843e-17 7.404116320743692e-18 1147/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/8517/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/695/5719/5704/6233/5716/7311/5694/3551/5693/5721/5696/5691/7314 52 Cottontail_rabbit_papillomavirus R-HSA-9607240 FLT3 Signaling 97/1598 267/10654 2.4828002485154237e-18 1.735304772625486e-17 8.315598918472712e-18 5718/5689/5684/4893/5290/5720/5682/1844/5604/2904/5747/153090/5700/3815/122706/5707/10048/5690/5594/5717/9491/23198/409/5908/143471/5706/2064/5705/10197/8452/6776/7316/10213/5709/9978/1950/5695/2263/4233/84078/5714/6714/9861/5715/5519/5711/2261/5701/5688/5159/5687/3558/3717/2247/5685/5683/5698/5708/5692/5686/5713/408/5699/1445/5710/2264/5702/2066/5719/208/5704/6233/5527/5716/7311/8826/5518/1956/60/1843/3845/6777/5694/3265/369/4763/5693/5721/5696/5691/5245/7529/5156/7314/5595/5515/5516 97 Cottontail_rabbit_papillomavirus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 50/1598 93/10654 2.6913218593822308e-18 1.8611416244510982e-17 8.918610450194527e-18 8454/1147/3665/3725/8945/5601/351/4790/5606/5604/5594/4214/6500/8517/7316/79155/5970/4792/4793/3146/5519/5598/1432/23291/5602/6195/57162/10454/2002/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 50 Cottontail_rabbit_papillomavirus R-HSA-975155 MyD88 dependent cascade initiated on endosome 50/1598 93/10654 2.6913218593822308e-18 1.8611416244510982e-17 8.918610450194527e-18 8454/1147/3665/3725/8945/5601/351/4790/5606/5604/5594/4214/6500/8517/7316/79155/5970/4792/4793/3146/5519/5598/1432/23291/5602/6195/57162/10454/2002/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 50 Cottontail_rabbit_papillomavirus R-HSA-983169 Class I MHC mediated antigen processing & presentation 121/1598 371/10654 3.321074761114252e-18 2.2845498488296462e-17 1.094758716267579e-17 8454/57154/1147/5718/197131/23352/5689/8945/5684/5720/142678/55070/5682/7319/5700/122706/7321/5707/991/10273/8697/7320/5690/5717/9491/23198/6500/10533/143471/5706/5705/26259/10197/8517/7336/26263/64750/8452/7316/10213/5709/9978/5695/80196/22872/4008/11059/84078/7337/5714/26272/7704/8651/3093/51433/9861/25831/5715/5711/23327/5701/5688/5687/6502/23291/5685/10616/5683/3309/5698/5708/5692/5686/5713/25898/55294/5699/79654/5710/7428/5702/22954/83737/9040/695/5719/10075/64682/80176/8924/51191/5704/6233/56658/51434/5716/10425/51343/7311/9871/868/80204/57520/6396/7334/5930/5694/3551/23014/7332/5693/5721/5696/23608/55585/5691/51132/9820/7314/996/140691 121 Cottontail_rabbit_papillomavirus R-HSA-382556 ABC-family proteins mediated transport 53/1598 103/10654 3.4369254585170256e-18 2.3518646985768337e-17 1.1270160638289505e-17 5718/5689/5684/5720/5682/5700/122706/5707/5243/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/8894/5683/5698/5708/5692/5686/5713/5699/6400/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 53 Cottontail_rabbit_papillomavirus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 51/1598 97/10654 4.426900467101376e-18 3.013520265886197e-17 1.4440821150906353e-17 8454/1147/3665/3725/8945/5601/351/4790/5606/5604/5594/4214/6500/8411/8517/7316/79155/5970/4792/4793/3146/5519/5598/1432/23291/5602/6195/57162/10454/2002/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 51 Cottontail_rabbit_papillomavirus R-HSA-450294 MAP kinase activation 40/1598 64/10654 4.45671782418883e-18 3.0180985472615553e-17 1.4462760323928848e-17 8454/1147/3725/8945/5601/4790/5606/5604/5594/6500/8517/7316/79155/5519/5598/1432/23291/5602/6195/10454/2002/7189/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595/5515/5516 40 Cottontail_rabbit_papillomavirus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 50/1598 94/10654 4.9261188544842556e-18 3.3187821354695475e-17 1.5903639275193338e-17 8454/1147/3665/3725/8945/5601/351/4790/5606/5604/7321/5594/6500/841/8517/7098/7316/79155/5970/4792/4793/3146/5519/5598/1432/23291/5602/6195/10454/2002/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595/5515/5516 50 Cottontail_rabbit_papillomavirus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 51/1598 98/10654 7.908472058448012e-18 5.27365968387324e-17 2.5271433269476728e-17 8454/1147/3725/8945/5601/351/4790/5606/5604/5594/4214/6500/8517/7316/79155/5970/4792/4793/8651/3146/5519/5598/1432/23291/5602/6195/57162/10454/2002/695/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 51 Cottontail_rabbit_papillomavirus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 51/1598 98/10654 7.908472058448012e-18 5.27365968387324e-17 2.5271433269476728e-17 8454/1147/3725/8945/5601/351/4790/5606/5604/5594/4214/6500/8517/7316/79155/5970/4792/4793/8651/3146/5519/5598/1432/23291/5602/6195/57162/10454/2002/695/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 51 Cottontail_rabbit_papillomavirus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 54/1598 108/10654 8.820317625304718e-18 5.851855399123485e-17 2.804215328376333e-17 7124/2308/7291/596/2309/7184/207/5451/7422/3553/2625/4582/5743/3091/4318/3726/4312/3383/301/6097/6657/6778/3576/332/3688/4313/3565/6774/5443/1026/6772/8651/4609/4988/3552/79923/3717/598/2247/3320/595/7157/2353/604/6347/7040/6935/7431/3312/3569/3162/4170/3586/4692 54 Cottontail_rabbit_papillomavirus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 49/1598 92/10654 9.900096211701013e-18 6.535063509441023e-17 3.131609381160076e-17 8454/1147/3725/8945/5601/351/4790/5606/5604/5594/4214/6500/8517/7316/79155/5970/4792/4793/3146/5519/5598/1432/23291/5602/6195/57162/10454/2002/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 49 Cottontail_rabbit_papillomavirus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 32/1598 44/10654 1.0939752435936743e-17 7.185053484306192e-17 3.4430852681207944e-17 892/7027/7321/6497/3726/64750/7316/9611/9612/1024/6667/5933/4092/4609/4089/22938/23327/8812/4088/1874/142/3065/6498/4087/6233/1025/1030/7311/25937/7314/4221/5054 32 Cottontail_rabbit_papillomavirus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 142/1598 473/10654 1.369665073510199e-17 8.950761255389151e-17 4.28921430915036e-17 627/2963/3643/5434/5590/4893/857/5290/85440/5241/5579/5604/1499/2904/5747/3815/5567/5430/10048/10273/207/7422/2060/5578/5045/5594/5568/3315/5908/3178/51741/23385/4318/2064/6778/6696/6776/3688/7316/1950/9611/3185/6774/2263/11059/4233/102/6772/6714/2099/8651/5664/3910/5566/2962/5519/5598/1432/2261/867/5159/4670/2567/4067/3717/2321/2247/4914/10000/9146/3320/4846/6195/4803/8471/1445/1111/2264/5603/3630/2002/998/2066/83737/3481/6868/3925/6285/208/83464/6233/1398/5867/3187/5580/2324/2475/7409/6093/1385/6196/7311/57610/3932/3479/1759/5518/23163/1213/3791/387/1956/1211/60/8851/29924/581/6197/3845/5600/55851/51107/6777/3265/6300/3071/1020/7057/3480/5663/10254/5725/51231/7529/5156/7314/5595/5515/25920/6387/5516/5607 142 Cottontail_rabbit_papillomavirus R-HSA-68886 M Phase 125/1598 395/10654 1.3878450179468563e-17 9.024444967445479e-17 4.324523622301019e-17 10844/4000/115106/5718/5689/11130/22995/5684/5903/5720/5579/5682/22981/9631/7531/23383/1459/55869/1058/5700/122706/7321/5707/991/203068/51807/7532/1454/2801/8697/5690/5578/9212/5594/5717/9491/23198/79172/5925/1460/23244/7277/143471/5706/5705/10197/6232/332/7443/7316/10213/5709/891/5695/5501/1457/983/5714/4927/51433/9861/5566/3796/8615/5715/5519/5711/5701/5688/699/5687/7846/5685/7283/5683/7444/5698/5708/3320/5692/5686/5713/80097/8243/9126/5699/5710/5702/10540/5520/5719/64682/9232/5704/6233/5527/23133/51434/5716/701/7514/7311/54930/5518/10383/55835/5347/84790/6396/9662/5694/1453/6418/8481/5693/5721/5696/7280/5691/8480/7314/996/5595/5515/5516 125 Cottontail_rabbit_papillomavirus R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus 23/1598 25/10654 2.1619331205359576e-17 1.398834944822028e-16 6.703231926622693e-17 142678/4904/182/23385/7316/1950/4854/3714/54492/102/5664/9148/83464/6233/7311/57534/1956/54567/55851/51107/5663/28514/7314 23 Cottontail_rabbit_papillomavirus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 46/1598 84/10654 2.331316067624384e-17 1.5010000494507732e-16 7.19280819412242e-17 9318/6118/902/7515/5982/6613/7336/86/8450/7316/9978/4331/5111/1643/6119/7341/1642/2965/5985/142/2068/10987/2071/5984/7329/6233/2067/51426/2873/2968/7311/6612/60/5983/6117/7334/5981/10714/1022/5886/7508/7314/51138/8451/8554/7528 46 Cottontail_rabbit_papillomavirus R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 20/1598 20/10654 3.000427269108349e-17 1.9223325689826533e-16 9.211838106911598e-17 2648/23462/55534/3280/84441/10046/22938/8850/1387/4088/59/2033/4855/4853/9794/2324/23493/388585/3516/4851 20 Cottontail_rabbit_papillomavirus R-HSA-5696398 Nucleotide Excision Repair 54/1598 111/10654 4.2054028200550185e-17 2.6812007247862975e-16 1.2848342377061544e-16 9318/6118/5434/902/2074/27339/5430/7515/5982/6613/7336/86/8450/7316/9978/4331/5111/1643/6119/7341/1161/1642/2965/5985/2033/142/2068/10987/2071/5984/7329/6233/2067/51426/2873/2968/7311/6612/60/5983/6117/7334/5981/10714/7874/1022/8178/5886/7508/7314/51138/8451/8554/7528 54 Cottontail_rabbit_papillomavirus R-HSA-2408522 Selenoamino acid metabolism 56/1598 118/10654 4.588902792850042e-17 2.9115028884733035e-16 1.395195279379548e-16 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/191/6230/6222/6152/6136/6125/6154/51065/6141/6202/6232/6160/6155/6175/6218/6209/6231/6229/6130/6142/6204/7965/140801/6156/6143/6181/6124/6207/6233/7311/6223/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/7296 56 Cottontail_rabbit_papillomavirus R-HSA-9006936 Signaling by TGF-beta family members 51/1598 102/10654 7.246446528877484e-17 4.575413339730856e-16 2.192542936527894e-16 4093/57154/5590/892/7027/9765/7321/6497/10273/4738/5045/4086/3726/64750/130399/7316/9611/5501/9612/1024/6667/5933/4092/4609/4089/22938/23327/867/8812/7046/4088/650/1874/142/3065/6498/9958/9040/4087/5499/6233/7514/1025/1030/7311/25937/387/7040/7314/4221/5054 51 Cottontail_rabbit_papillomavirus R-HSA-2979096 NOTCH2 Activation and Transmission of Signal to the Nucleus 21/1598 22/10654 8.408544100892352e-17 5.283638048012646e-16 2.53192496965129e-16 142678/182/23385/7316/3714/54492/1272/102/5664/9148/4853/83464/6233/7311/57534/54567/55851/51107/5663/28514/7314 21 Cottontail_rabbit_papillomavirus R-HSA-6804758 Regulation of TP53 Activity through Acetylation 25/1598 30/10654 1.4207400468293915e-16 8.884723642134043e-16 4.257569014673825e-16 23774/64769/7862/3622/9219/207/5931/84289/1108/29117/5928/27154/57459/10000/54815/2033/7994/3066/3065/7157/1107/5371/208/5300/53615 25 Cottontail_rabbit_papillomavirus R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 53/1598 112/10654 3.7385876973045353e-016 2.3268257716081083e-15 1.1150173834066158e-15 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/6152/6136/6125/6154/51065/6141/6202/6232/6160/6155/6175/6218/6209/6231/6229/6130/6142/6204/140801/6156/6143/6181/6124/6207/6233/7311/6223/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122 53 Cottontail_rabbit_papillomavirus R-HSA-166166 MyD88-independent TLR4 cascade 49/1598 99/10654 5.000259965225751e-16 3.0827074408254984e-15 1.4772366828745393e-15 8454/1147/3665/3725/8945/5601/351/4790/5606/5604/7321/5594/6500/841/8517/7316/79155/5970/4792/4793/3146/5519/5598/1432/23291/5602/6195/10454/2002/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595/5515/5516 49 Cottontail_rabbit_papillomavirus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 49/1598 99/10654 5.000259965225751e-16 3.0827074408254984e-15 1.4772366828745393e-15 8454/1147/3665/3725/8945/5601/351/4790/5606/5604/7321/5594/6500/841/8517/7316/79155/5970/4792/4793/3146/5519/5598/1432/23291/5602/6195/10454/2002/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595/5515/5516 49 Cottontail_rabbit_papillomavirus R-HSA-5628897 TP53 Regulates Metabolic Genes 45/1598 86/10654 5.266042625857181e-16 3.231322869481378e-15 1.5484533542797244e-15 27161/5563/27165/83667/7531/7532/207/10971/9997/57690/51422/7249/27327/7295/7533/2810/53632/27244/192670/7534/2539/54205/143686/5571/10000/2877/10128/5728/54541/192669/7157/8626/23112/208/10542/2475/5562/4343/50484/26523/5564/5052/5565/7529/7296 45 Cottontail_rabbit_papillomavirus R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 20/1598 21/10654 5.410418756447301e-16 3.30440061433487e-15 1.5834722873025797e-15 7832/4849/4869/4850/9337/10769/25904/246175/4848/23019/28984/995/7157/55571/55835/5325/57472/85456/29883/1263 20 Cottontail_rabbit_papillomavirus R-HSA-8986944 Transcriptional Regulation by MECP2 37/1598 62/10654 7.09383101772784e-16 4.312389367521064e-15 2.0665015694237774e-15 27161/627/8841/2571/2290/79718/5468/2904/9212/57690/27327/6657/192670/54487/9611/28996/2874/4233/9612/5566/4988/6907/3064/2593/5728/1392/192669/3066/3065/23112/1385/25942/4343/6750/26523/814/28514 37 Cottontail_rabbit_papillomavirus R-HSA-5696395 Formation of Incision Complex in GG-NER 30/1598 43/10654 7.48689551855867e-16 4.530265019794528e-15 2.1709078136171584e-15 6118/902/6613/7336/8450/7316/9978/4331/1643/6119/7341/1642/2965/142/2068/2071/7329/6233/2067/2968/7311/6612/6117/7334/1022/5886/7508/7314/8451/8554 30 Cottontail_rabbit_papillomavirus R-HSA-1912420 Pre-NOTCH Processing in Golgi 18/1598 18/10654 1.3603783441615203e-15 8.193615188106485e-15 3.926389108785373e-15 4242/487/5045/3955/10402/488/4854/5986/6484/5870/489/4855/6400/4853/2683/6487/4851/10959 18 Cottontail_rabbit_papillomavirus R-HSA-448424 Interleukin-17 signaling 40/1598 72/10654 1.4738326872683096e-15 8.836235423209545e-15 4.234333408617307e-15 8454/1147/3725/8945/5601/4790/5606/5604/5594/6500/8517/7316/79155/5519/5598/1432/23291/5602/6195/10454/2002/7189/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595/5515/5516 40 Cottontail_rabbit_papillomavirus R-HSA-114452 Activation of BH3-only proteins 24/1598 30/10654 3.4332511668042347e-15 2.048976837905541e-14 9.818718789947222e-15 23368/27113/596/10018/7531/7027/7532/207/10971/7533/2810/7534/1869/5366/10000/5534/7157/8626/208/7161/5599/7159/637/7529 24 Cottontail_rabbit_papillomavirus R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 19/1598 20/10654 3.4716596683902912e-15 2.062481448448232e-14 9.883433027235517e-15 23368/27113/55240/472/5366/84883/147923/1387/51499/94241/7157/8626/63970/7161/581/7159/637/665/27166 19 Cottontail_rabbit_papillomavirus R-HSA-9006931 Signaling by Nuclear Receptors 98/1598 299/10654 4.2382306441887285e-15 2.5065011094817505e-14 1.2011179963287896e-14 3727/27161/3725/2354/2963/3838/596/5434/5590/4893/8841/857/112724/5290/7090/79718/5241/2309/5747/5160/5430/207/10901/5451/2625/57690/5594/6722/1027/3315/27327/4318/5481/6720/192670/2100/4313/1950/9611/5469/2874/1655/9612/6667/6714/2099/4609/2962/7391/8850/10524/1387/6907/10000/3320/2033/8243/4846/9126/595/2783/4602/8312/192669/3065/2002/2066/861/23028/23112/208/10498/3326/7514/1385/1025/2353/10499/1386/6908/1956/3169/4343/3845/1071/3276/7392/3265/26523/8202/8648/3480/2791/2288/10728/5595/7528/6387 98 Cottontail_rabbit_papillomavirus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 56/1598 129/10654 6.2648580161969996e-15 3.688364606833098e-14 1.767468240700434e-14 8454/1147/3665/3725/8945/5601/351/4790/5606/5604/7321/5336/5594/4214/6500/841/8517/7316/79155/5970/4792/4793/8651/3146/5519/5598/1432/23291/5602/6195/57162/10454/2002/695/7189/6285/5609/6233/1385/2353/6196/7311/1759/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 56 Cottontail_rabbit_papillomavirus R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 27/1598 38/10654 1.0430634876868813e-14 6.113381069088582e-14 2.9295387074519445e-14 1912/6597/1459/8535/6045/80012/1460/6598/6599/86/28996/1457/1911/6603/84733/8289/2033/6605/6602/57332/861/648/6601/23466/23429/55193/6015 27 Cottontail_rabbit_papillomavirus R-HSA-6804760 Regulation of TP53 Activity through Methylation 18/1598 19/10654 2.220962177450013e-14 1.2958917705031996e-13 6.209927140896418e-14 133383/11200/472/79813/7316/4194/56950/2033/7157/91875/6233/7311/10419/133746/26013/10919/7314/4193 18 Cottontail_rabbit_papillomavirus R-HSA-167161 HIV Transcription Initiation 30/1598 47/10654 3.0318310936054145e-14 1.722870973627077e-13 8.256016021488428e-14 6884/6875/2963/5434/902/5430/6874/6878/6872/4331/8148/6879/2962/54457/83860/2965/2068/2071/6873/2968/6881/51616/6880/6908/6883/6882/2961/138474/1022/6877 30 Cottontail_rabbit_papillomavirus R-HSA-167162 RNA Polymerase II HIV Promoter Escape 30/1598 47/10654 3.0318310936054145e-14 1.722870973627077e-13 8.256016021488428e-14 6884/6875/2963/5434/902/5430/6874/6878/6872/4331/8148/6879/2962/54457/83860/2965/2068/2071/6873/2968/6881/51616/6880/6908/6883/6882/2961/138474/1022/6877 30 Cottontail_rabbit_papillomavirus R-HSA-73776 RNA Polymerase II Promoter Escape 30/1598 47/10654 3.0318310936054145e-14 1.722870973627077e-13 8.256016021488428e-14 6884/6875/2963/5434/902/5430/6874/6878/6872/4331/8148/6879/2962/54457/83860/2965/2068/2071/6873/2968/6881/51616/6880/6908/6883/6882/2961/138474/1022/6877 30 Cottontail_rabbit_papillomavirus R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 30/1598 47/10654 3.0318310936054145e-14 1.722870973627077e-13 8.256016021488428e-14 6884/6875/2963/5434/902/5430/6874/6878/6872/4331/8148/6879/2962/54457/83860/2965/2068/2071/6873/2968/6881/51616/6880/6908/6883/6882/2961/138474/1022/6877 30 Cottontail_rabbit_papillomavirus R-HSA-75953 RNA Polymerase II Transcription Initiation 30/1598 47/10654 3.0318310936054145e-14 1.722870973627077e-13 8.256016021488428e-14 6884/6875/2963/5434/902/5430/6874/6878/6872/4331/8148/6879/2962/54457/83860/2965/2068/2071/6873/2968/6881/51616/6880/6908/6883/6882/2961/138474/1022/6877 30 Cottontail_rabbit_papillomavirus R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 30/1598 47/10654 3.0318310936054145e-14 1.722870973627077e-13 8.256016021488428e-14 6884/6875/2963/5434/902/5430/6874/6878/6872/4331/8148/6879/2962/54457/83860/2965/2068/2071/6873/2968/6881/51616/6880/6908/6883/6882/2961/138474/1022/6877 30 Cottontail_rabbit_papillomavirus R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 21/1598 25/10654 3.059231777599222e-14 1.7309159884511615e-13 8.294567818052119e-14 23129/2648/23462/55534/3280/84441/10046/4854/6772/10320/22938/8850/1387/2173/26508/2033/9794/23493/388585/3516/4851 21 Cottontail_rabbit_papillomavirus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 24/1598 32/10654 4.477403979470827e-14 2.5223995694691256e-13 1.2087365552564165e-13 892/7027/3726/7316/1024/6667/5933/4092/4609/4089/22938/8812/4088/1874/3065/4087/6233/1025/1030/7311/25937/7314/4221/5054 24 Cottontail_rabbit_papillomavirus R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 31/1598 51/10654 7.962178853067134e-14 4.466338094832079e-13 2.1402739632143412e-13 6203/6194/6191/8666/6217/6230/6222/8668/8667/51065/8662/10480/6202/6232/6218/6209/6231/6229/6204/8894/6207/6233/6223/3646/51386/6188/6189/8665/6201/6187/6208 31 Cottontail_rabbit_papillomavirus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 40/1598 79/10654 9.423727747516492e-14 5.263594942736775e-13 2.5223202922952375e-13 9318/6118/5434/902/2074/27339/5430/7515/5982/8450/7316/9978/4331/5111/6119/1161/1642/2965/5985/2033/2068/10987/2071/5984/6233/2067/51426/2873/2968/7311/5983/6117/5981/10714/7874/1022/8178/7314/51138/8451 40 Cottontail_rabbit_papillomavirus R-HSA-9022692 Regulation of MECP2 expression and activity 24/1598 33/10654 1.4086971815636134e-13 7.834754111930395e-13 3.754422499576036e-13 27161/8841/2290/79718/9212/57690/27327/192670/9611/28996/2874/9612/5566/6907/3064/192669/3066/3065/23112/1385/25942/4343/26523/814 24 Cottontail_rabbit_papillomavirus R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 17/1598 18/10654 1.4162132276230258e-13 7.843180883488538e-13 3.758460617465211e-13 7027/25946/2810/5934/891/983/6790/5933/5111/1647/2033/995/1874/7157/10498/581/3276 17 Cottontail_rabbit_papillomavirus R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 68/1598 185/10654 1.6868128302261534e-13 9.302381304242965e-13 4.4577110103689155e-13 6158/6138/6144/2091/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/1454/6152/6136/27043/6125/6154/51065/6141/6202/6232/6160/55272/6155/6175/6218/6209/10200/6231/6229/6130/6142/6204/23481/140801/6156/6143/6181/6124/6207/10969/6233/7311/6223/26168/11340/6188/6189/26354/6135/6201/1453/9045/6187/4691/23016/6168/6208/54512/6137/10813/6122 68 Cottontail_rabbit_papillomavirus R-HSA-3232118 SUMOylation of transcription factors 18/1598 20/10654 1.908512807294881e-13 1.0480782517371469e-12 5.022402124460212e-13 7020/6670/7021/1029/9112/51588/3090/6613/7341/7022/7157/7329/7158/6612/9063/4286/4193/8554 18 Cottontail_rabbit_papillomavirus R-HSA-73762 RNA Polymerase I Transcription Initiation 29/1598 47/10654 2.9398701742251324e-13 1.607703061804288e-12 7.704130163681805e-13 5434/902/9015/2648/2074/9112/9219/9014/5931/51082/4331/9013/1108/8850/5928/57459/2965/54815/2068/3066/3065/2071/1107/2968/57504/6908/53615/1022/10919 29 Cottontail_rabbit_papillomavirus R-HSA-168898 Toll-like Receptor Cascades 60/1598 155/10654 3.353555317066109e-13 1.8262903330855855e-12 8.751602691466381e-13 8454/1147/3665/3725/8945/5601/351/4790/5606/5604/7184/7321/5336/5594/4214/6500/8411/841/8517/7098/7316/79155/5970/4792/4793/6279/8651/3146/5519/5598/1432/23291/5602/6195/57162/10454/2002/695/7189/6285/5609/6233/1385/2353/6196/7311/1759/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 60 Cottontail_rabbit_papillomavirus R-HSA-2691230 Signaling by NOTCH1 HD Domain Mutants in Cancer 15/1598 15/10654 4.136379717754069e-13 2.233986897150648e-12 1.0705288960694525e-12 142678/182/7316/3714/54492/102/9148/6868/6233/7311/57534/54567/4851/28514/7314 15 Cottontail_rabbit_papillomavirus R-HSA-2691232 Constitutive Signaling by NOTCH1 HD Domain Mutants 15/1598 15/10654 4.136379717754069e-13 2.233986897150648e-12 1.0705288960694525e-12 142678/182/7316/3714/54492/102/9148/6868/6233/7311/57534/54567/4851/28514/7314 15 Cottontail_rabbit_papillomavirus R-HSA-2559580 Oxidative Stress Induced Senescence 52/1598 125/10654 4.610209648230097e-13 2.479336716188671e-12 1.1881007901842383e-12 1912/3725/1019/5601/5606/1029/7027/2146/8535/6045/57690/5594/27327/80012/5931/7295/192670/8550/7316/1869/1911/1871/4194/1031/5928/1432/84733/5602/23512/1021/57332/192669/7157/23135/23112/5609/6233/2353/1030/7311/4343/8726/5599/648/5600/23466/26523/3456/7314/6015/5595/4193 52 Cottontail_rabbit_papillomavirus R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 27/1598 42/10654 4.628601061591704e-13 2.479336716188671e-12 1.1881007901842383e-12 9070/51176/8945/6662/7090/1487/1499/207/5929/6657/7534/7316/7091/6934/324/3065/7088/208/57680/6233/7514/7311/7089/331/6659/7314/4221 27 Cottontail_rabbit_papillomavirus R-HSA-3371556 Cellular response to heat stress 42/1598 89/10654 4.976170606000645e-13 2.6546346865480987e-12 1.2721037639400144e-12 3303/6118/5903/573/9631/7531/1915/5594/3308/10049/1410/10013/545/472/3337/3313/3305/9532/4927/7415/6119/2932/1387/57805/3310/3309/3320/2033/7266/3326/2475/3306/23411/9529/6117/6396/3304/3312/2288/8480/10728/5595 42 Cottontail_rabbit_papillomavirus R-HSA-71291 Metabolism of amino acids and derivatives 109/1598 372/10654 5.808028699567123e-13 3.085810370054565e-12 1.4787236098598366e-12 6158/5718/5689/6138/6144/6203/5684/27165/9349/4736/1728/5720/6194/6191/6128/5682/51121/6132/6147/6129/5160/6217/5700/122706/5707/191/6230/6222/1743/6152/5690/6136/6125/5717/9491/23198/6154/51065/6141/143471/6202/5706/5705/10197/6232/6160/6155/10213/5709/6175/6218/5695/9380/6209/5714/6231/6229/9861/6130/5715/6142/5711/6204/5701/5688/5687/23474/5685/5683/5698/5708/7965/5692/5686/5713/2593/7054/140801/6156/5699/6143/5710/6181/6124/5702/6207/5719/5704/6233/5716/7311/6223/6188/6189/6135/6201/6303/5694/9045/6187/6168/5693/6208/5721/6137/5696/5691/6122/7296 109 Cottontail_rabbit_papillomavirus R-HSA-73893 DNA Damage Bypass 29/1598 48/10654 6.368990730536724e-13 3.370150155794129e-12 1.6149795374682937e-12 6118/7320/5982/7706/8450/7316/9978/11201/5111/9100/7415/6119/51455/1642/5985/25898/7398/5984/57599/6233/51426/7311/5983/6117/5981/10714/7314/51514/8451 29 Cottontail_rabbit_papillomavirus R-HSA-167172 Transcription of the HIV genome 37/1598 73/10654 7.696468308135014e-13 4.056162934972768e-12 1.9437175905519244e-12 6884/6875/2963/5434/902/5430/6874/6878/6749/6872/4331/8148/6879/2962/54457/8812/83860/2965/2068/2071/6873/2968/1025/6881/51616/6880/6908/11198/6883/51497/6882/2961/138474/1022/8178/6877/25920 37 Cottontail_rabbit_papillomavirus R-HSA-400253 Circadian Clock 36/1598 70/10654 8.913502766763732e-13 4.678694022554297e-12 2.2420351495347376e-12 8454/8945/8841/79718/1454/6500/3091/200186/6720/7316/9611/5469/5501/8553/1387/150094/2908/6907/1390/2033/5499/10498/6233/1385/7311/10499/23054/8864/1386/23411/1453/23373/8648/10891/7314/5054 36 Cottontail_rabbit_papillomavirus R-HSA-8868773 rRNA processing in the nucleus and cytosol 69/1598 195/10654 9.30184123322213e-13 4.863002596728529e-12 2.3303560142177547e-12 6158/6138/6144/2091/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/55226/6230/6222/1454/6152/6136/27043/6125/6154/51065/6141/6202/6232/6160/55272/6155/6175/6218/6209/10200/6231/6229/6130/6142/6204/23481/140801/6156/6143/6181/6124/6207/10969/6233/7311/6223/26168/11340/6188/6189/26354/6135/6201/1453/9045/6187/4691/23016/6168/6208/54512/6137/10813/6122 69 Cottontail_rabbit_papillomavirus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 22/1598 30/10654 1.1385943094684876e-12 5.928855627391686e-12 2.8411139196215146e-12 6118/7320/5982/8450/7316/9978/5111/6119/1642/5985/7398/5984/57599/6233/7311/5983/6117/5981/10714/7314/51514/8451 22 Cottontail_rabbit_papillomavirus R-HSA-1912422 Pre-NOTCH Expression and Processing 47/1598 109/10654 1.2870055446085636e-12 6.675064471442035e-12 3.1986979909861965e-12 1999/27161/3725/4242/23509/2648/7027/487/55534/5045/57690/27327/84441/51548/3955/10402/10046/192670/488/1869/4854/5986/6484/1871/5870/22938/8850/489/1387/2033/4855/595/6400/4853/192669/7157/861/2683/23112/9794/56983/6487/4343/26523/3516/4851/10959 47 Cottontail_rabbit_papillomavirus R-HSA-72649 Translation initiation complex formation 32/1598 58/10654 1.3296746104130439e-12 6.869109548655527e-12 3.291684598276518e-12 6203/6194/6191/8666/6217/6230/6222/8668/8667/51065/8662/10480/26986/6202/6232/6218/6209/6231/6229/6204/8894/6207/6233/6223/3646/51386/6188/6189/8665/6201/6187/6208 32 Cottontail_rabbit_papillomavirus R-HSA-72312 rRNA processing 71/1598 205/10654 1.4319718510825394e-12 7.368453580176688e-12 3.5309707890348574e-12 6158/6138/6144/2091/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/55226/6230/6222/1454/6152/6136/27043/6125/130916/6154/51065/6141/6202/6232/6160/55272/6155/6175/6218/54931/6209/10200/6231/6229/6130/6142/6204/23481/140801/6156/6143/6181/6124/6207/10969/6233/7311/6223/26168/11340/6188/6189/26354/6135/6201/1453/9045/6187/4691/23016/6168/6208/54512/6137/10813/6122 71 Cottontail_rabbit_papillomavirus R-HSA-162587 HIV Life Cycle 58/1598 152/10654 1.6979897424963704e-12 8.703029778206887e-12 4.17050112192091e-12 6884/6875/2963/5434/5903/7852/902/9631/3159/5430/6874/5045/7520/6878/6749/7316/6872/4331/4836/9397/4927/8148/6879/2962/23327/54457/8812/83860/2965/128866/2068/2071/6873/6233/2968/7514/1025/7311/6881/51616/6880/6908/7251/11198/6396/6883/1104/51497/2547/6882/2961/138474/1022/8178/8480/6877/7314/25920 58 Cottontail_rabbit_papillomavirus R-HSA-5696400 Dual Incision in GG-NER 26/1598 41/10654 2.0164660335222354e-12 1.0295004319584226e-11 4.933377014579483e-12 6118/5982/8450/7316/9978/5111/1643/6119/1642/2965/5985/142/2068/2071/5984/6233/2067/51426/2968/7311/5983/6117/5981/10714/7314/8451 26 Cottontail_rabbit_papillomavirus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 34/1598 65/10654 2.0421398144321613e-12 1.034525867233657e-11 4.957458953843885e-12 6118/5434/902/2074/27339/5430/7515/5982/8450/7316/9978/4331/5111/6119/1161/1642/2965/5985/2033/2068/2071/5984/6233/51426/2968/7311/5983/6117/5981/10714/7874/1022/7314/8451 34 Cottontail_rabbit_papillomavirus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 34/1598 65/10654 2.0421398144321613e-12 1.034525867233657e-11 4.957458953843885e-12 2176/3725/2963/5434/4436/8621/902/5430/6749/4292/545/472/4331/1643/5395/2962/9656/8812/2965/51755/2068/1111/2071/7157/2968/672/1025/2353/1386/11198/51497/1022/8178/25920 34 Cottontail_rabbit_papillomavirus R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 32/1598 59/10654 2.4910937664999217e-12 1.2570886304306554e-11 6.0239820811520156e-12 6203/6194/6191/8666/6217/6230/6222/8668/8667/51065/8662/10480/26986/6202/6232/6218/6209/6231/6229/6204/8894/6207/6233/6223/3646/51386/6188/6189/8665/6201/6187/6208 32 Cottontail_rabbit_papillomavirus R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 14/1598 14/10654 2.7784772851580366e-12 1.386057180038761e-11 6.642000741940666e-12 1017/9134/1820/57060/25946/1027/898/1869/890/1026/7157/8900/144455/79733 14 Cottontail_rabbit_papillomavirus R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 14/1598 14/10654 2.7784772851580366e-12 1.386057180038761e-11 6.642000741940666e-12 23368/25946/5457/207/54971/10848/5458/10000/7157/8626/208/7161/7159/51230 14 Cottontail_rabbit_papillomavirus R-HSA-8941856 RUNX3 regulates NOTCH signaling 14/1598 14/10654 2.7784772851580366e-12 1.386057180038761e-11 6.642000741940666e-12 2648/864/55534/3280/182/84441/10046/22938/8850/1387/2033/9794/3516/4851 14 Cottontail_rabbit_papillomavirus R-HSA-9018519 Estrogen-dependent gene expression 57/1598 150/10654 3.2297554462723614e-12 1.6050533719688123e-11 7.691432821821313e-12 3727/27161/3725/2354/2963/3838/596/5434/7090/5241/5430/5451/2625/57690/27327/192670/5469/1655/6667/2099/4609/2962/7391/8850/10524/1387/3320/2033/8243/9126/595/4602/8312/192669/3065/2066/861/23028/23112/10498/3326/1025/2353/10499/1386/6908/3169/4343/3276/7392/26523/8202/8648/2288/10728/7528/6387 57 Cottontail_rabbit_papillomavirus R-HSA-6782135 Dual incision in TC-NER 34/1598 66/10654 3.610595713470529e-12 1.787518408146205e-11 8.565807214971949e-12 6118/5434/902/2074/27339/5430/5982/8450/7316/9978/4331/5111/6119/1161/1642/2965/5985/2033/2068/2071/5984/6233/2067/51426/2968/7311/5983/6117/5981/10714/7874/1022/7314/8451 34 Cottontail_rabbit_papillomavirus R-HSA-162599 Late Phase of HIV Life Cycle 54/1598 139/10654 4.3508568249743e-12 2.1458754227326074e-11 1.0283057838568852e-11 6884/6875/2963/5434/5903/902/9631/5430/6874/5045/6878/6749/7316/6872/4331/4836/9397/4927/8148/6879/2962/23327/54457/8812/83860/2965/128866/2068/2071/6873/6233/2968/7514/1025/7311/6881/51616/6880/6908/7251/11198/6396/6883/1104/51497/6882/2961/138474/1022/8178/8480/6877/7314/25920 54 Cottontail_rabbit_papillomavirus R-HSA-205043 NRIF signals cell death from the nucleus 15/1598 16/10654 5.695016116899133e-12 2.7982654378899124e-11 1.3409317726770814e-11 4804/8878/23385/7316/5664/4803/7189/83464/6233/7311/5599/55851/51107/5663/7314 15 Cottontail_rabbit_papillomavirus R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 39/1598 84/10654 6.43141957978586e-12 3.136516936858253e-11 1.5030222505783923e-11 7124/1019/8841/4790/79718/5468/892/9440/6721/1051/7471/6720/6837/3952/688/9611/5469/81857/1050/5970/9612/1024/9314/1387/6907/9439/2033/9967/7026/10498/112950/10499/23054/7040/9412/8202/8648/1959/10891 39 Cottontail_rabbit_papillomavirus R-HSA-674695 RNA Polymerase II Pre-transcription Events 39/1598 84/10654 6.43141957978586e-12 3.136516936858253e-11 1.5030222505783923e-11 6884/6875/2963/5434/902/6830/5430/6874/6878/6749/6872/4331/8148/6879/2962/54457/8812/83860/2965/2068/2071/6873/2968/1025/6881/51616/6880/6908/11198/6883/51497/6882/2961/138474/1022/8178/55840/6877/25920 39 Cottontail_rabbit_papillomavirus R-HSA-72702 Ribosomal scanning and start codon recognition 31/1598 58/10654 9.183150920493712e-12 4.4618506517045657e-11 2.1381235756970295e-11 6203/6194/6191/8666/6217/6230/6222/8668/8667/51065/8662/10480/6202/6232/6218/6209/6231/6229/6204/8894/6207/6233/6223/3646/51386/6188/6189/8665/6201/6187/6208 31 Cottontail_rabbit_papillomavirus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 22/1598 32/10654 9.249545710324102e-12 4.477465275330964e-11 2.1456061199387295e-11 57154/10273/4738/5045/64750/7316/5501/4092/4089/23327/867/7046/4088/9958/9040/4087/5499/6233/7514/7311/7040/7314 22 Cottontail_rabbit_papillomavirus R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13/1598 13/10654 1.8653486934616198e-11 8.996349602783531e-11 4.3110602936867895e-11 7531/7532/10971/7533/2810/11200/7534/891/983/995/1111/7465/7529 13 Cottontail_rabbit_papillomavirus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 36/1598 77/10654 3.2410862355333056e-11 1.5573895992066288e-10 7.463027516030638e-11 1912/5903/9631/1029/7486/8535/51564/6045/51588/80012/6613/6996/1911/641/6672/4927/9656/7341/84733/8243/9126/57332/142/7329/5371/8924/672/6612/9063/6117/6396/648/8480/7508/6015/8554 36 Cottontail_rabbit_papillomavirus R-HSA-5655862 Translesion synthesis by POLK 15/1598 17/10654 4.1658828189916756e-11 1.979930488880771e-10 9.487847951387739e-11 6118/5982/7316/5111/6119/51455/5985/5984/6233/51426/7311/5983/6117/5981/7314 15 Cottontail_rabbit_papillomavirus R-HSA-5656121 Translesion synthesis by POLI 15/1598 17/10654 4.1658828189916756e-11 1.979930488880771e-10 9.487847951387739e-11 6118/5982/7316/11201/5111/6119/51455/5985/5984/6233/7311/5983/6117/5981/7314 15 Cottontail_rabbit_papillomavirus R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 15/1598 17/10654 4.1658828189916756e-11 1.979930488880771e-10 9.487847951387739e-11 2308/857/2290/2309/57060/4303/1027/5934/1026/901/4089/1647/9314/4088/4087 15 Cottontail_rabbit_papillomavirus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 21/1598 31/10654 4.299407711243354e-11 2.0359876371721245e-10 9.7564744019443e-11 3725/5601/5594/5519/5598/1432/5602/6195/2002/1385/2353/6196/5518/1386/6197/5599/5600/51231/5595/5515/5516 21 Cottontail_rabbit_papillomavirus R-HSA-1236394 Signaling by ERBB4 30/1598 58/10654 5.925103005941723e-11 2.7957074472078814e-10 1.3397059808228483e-10 4893/5290/5241/51741/23385/6776/7316/1950/9611/11059/6714/2099/5664/2567/2066/83737/6868/3925/6285/83464/6233/7311/1956/3845/55851/51107/3265/5663/7314/6387 30 Cottontail_rabbit_papillomavirus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 29/1598 55/10654 6.70477473916748e-11 3.152208843198524e-10 1.5105418287787397e-10 1147/834/596/351/4790/842/58484/7295/841/8517/7316/5970/7128/1432/598/10628/5603/10454/83737/7189/6233/3326/7311/5600/7334/1540/3551/6300/7314 29 Cottontail_rabbit_papillomavirus R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 12/1598 12/10654 1.2516419165081049e-10 5.863426469089938e-10 2.80976019740548e-10 23368/8793/3486/355/8794/124446/8797/7157/8626/7161/7159/8795 12 Cottontail_rabbit_papillomavirus R-HSA-9009391 Extra-nuclear estrogen signaling 35/1598 77/10654 1.6223913632737e-10 7.573091113566878e-10 3.6290333125859077e-10 596/5590/4893/857/5290/2309/5747/207/5594/6722/1027/3315/4318/2100/4313/1950/6714/2099/10000/3320/4846/595/2783/2002/208/7514/1385/2353/1956/3845/3276/3265/3480/2791/5595 35 Cottontail_rabbit_papillomavirus R-HSA-5619115 Disorders of transmembrane transporters 60/1598 176/10654 1.6410969946393684e-10 7.633145096062828e-10 3.657811244841447e-10 5718/5689/5684/5903/5720/5682/9631/5700/122706/5707/5690/285195/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/5695/5714/4927/7415/9861/5715/5711/5701/5688/6505/5687/5685/5683/5698/5708/5692/5686/5713/5699/6400/5710/5702/6514/5719/5704/6233/5716/7311/6396/5694/5693/5721/5696/5691/8480/6513/7314 60 Cottontail_rabbit_papillomavirus R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 13/1598 14/10654 2.250286123775721e-10 1.0429517602038537e-9 4.997835922532863e-10 23368/79370/9540/332/64065/5876/7157/8626/604/7161/7159/10397/5875 13 Cottontail_rabbit_papillomavirus R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 18/1598 25/10654 2.2646106091614914e-10 1.04588200218165e-9 5.01187767324191e-10 1017/902/2305/891/890/4331/983/5519/995/5520/8900/7514/5518/5347/7465/1022/5515/5516 18 Cottontail_rabbit_papillomavirus R-HSA-110312 Translesion synthesis by REV1 14/1598 16/10654 2.472247085618255e-10 1.1297996296863846e-9 5.41401183637417e-10 6118/5982/7316/5111/6119/51455/5985/5984/6233/7311/5983/6117/5981/7314 14 Cottontail_rabbit_papillomavirus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 14/1598 16/10654 2.472247085618255e-10 1.1297996296863846e-9 5.41401183637417e-10 8454/1147/8945/4790/5604/6500/8517/7316/79155/23291/6233/7311/3551/7314 14 Cottontail_rabbit_papillomavirus R-HSA-9614657 FOXO-mediated transcription of cell death genes 14/1598 16/10654 2.472247085618255e-10 1.1297996296863846e-9 5.41401183637417e-10 2308/27113/2309/10018/4802/4303/1649/4800/10370/1387/6794/2033/4801/604 14 Cottontail_rabbit_papillomavirus R-HSA-72766 Translation 85/1598 291/10654 2.667932050289735e-10 1.2149781148880432e-9 5.822188042994287e-10 6158/6138/6144/5464/6203/9349/4736/6194/6191/6128/51121/6132/1938/6147/56945/8666/6129/1915/6217/1936/6230/6222/6152/6136/79590/8668/64432/8667/6125/6154/51065/8662/6141/10480/26986/6202/6232/6160/6155/63931/6175/6218/9669/6209/6231/6229/6130/8890/6142/6204/64969/54148/23107/8894/7965/140801/6156/6143/6181/6124/28973/6207/64978/51116/6233/28957/64975/7311/6223/3646/51386/6188/6189/8665/6135/6201/9045/51649/6187/64965/6168/6208/6137/6122/55037 85 Cottontail_rabbit_papillomavirus R-HSA-73887 Death Receptor Signalling 51/1598 141/10654 3.598292540372896e-10 1.6329751216206164e-9 7.825234142989303e-10 9181/7124/1147/4804/8841/4790/10018/7531/29/8793/8878/1894/355/23385/841/27005/8517/9500/7316/9828/5970/4792/5664/8797/7128/9099/843/836/10616/8837/4803/10454/3066/3065/7189/6868/83464/6233/7409/7311/26574/387/331/5599/55851/51107/1540/3551/8795/5663/7314 51 Cottontail_rabbit_papillomavirus R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 18/1598 26/10654 6.326999129034605e-10 2.8613798829232627e-9 1.3711762818341251e-9 80010/83990/5888/9156/1763/7486/10111/675/472/580/116028/641/10524/4683/79728/672/5932/7156 18 Cottontail_rabbit_papillomavirus R-HSA-193692 Regulated proteolysis of p75NTR 11/1598 11/10654 8.393966551604125e-10 3.757162425666641e-9 1.800436228624533e-9 4804/4790/23385/5970/5664/7189/6868/83464/55851/51107/5663 11 Cottontail_rabbit_papillomavirus R-HSA-9013700 NOTCH4 Activation and Transmission of Signal to the Nucleus 11/1598 11/10654 8.393966551604125e-10 3.757162425666641e-9 1.800436228624533e-9 182/23385/7534/102/5664/4855/83464/54567/55851/51107/5663 11 Cottontail_rabbit_papillomavirus R-HSA-9614399 Regulation of localization of FOXO transcription factors 11/1598 11/10654 8.393966551604125e-10 3.757162425666641e-9 1.800436228624533e-9 2308/2309/7532/207/10971/4303/2810/7534/10000/208/7529 11 Cottontail_rabbit_papillomavirus R-HSA-110320 Translesion Synthesis by POLH 15/1598 19/10654 8.795430198731098e-10 3.923422276362303e-9 1.8801081258289936e-9 6118/5982/7316/5111/7415/6119/5985/25898/5984/6233/7311/5983/6117/5981/7314 15 Cottontail_rabbit_papillomavirus R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 19/1598 29/10654 8.871458201723986e-10 3.943876146140561e-9 1.8899096419712754e-9 2308/2309/4303/23410/4287/181/6720/5443/4089/4088/2908/4852/3630/3066/3065/6648/4087/25942/10891 19 Cottontail_rabbit_papillomavirus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 17/1598 24/10654 1.1004218974040678e-9 4.875428542058022e-9 2.336310540429689e-9 596/2309/5747/207/5594/6722/1027/1950/10000/595/2002/208/7514/1385/2353/1956/5595 17 Cottontail_rabbit_papillomavirus R-HSA-8953750 Transcriptional Regulation by E2F6 21/1598 35/10654 1.2237958529251823e-9 5.403720201936532e-9 2.5894684654711363e-9 5888/7027/2146/6045/80012/5931/79813/1869/1911/5928/23512/1111/672/5932/8726/648/317/23429/10919/6015/6241 21 Cottontail_rabbit_papillomavirus R-HSA-166520 Signaling by NTRKs 40/1598 101/10654 1.3389774369187274e-9 5.89240239075009e-9 2.8236454898693702e-9 627/4893/5290/5604/2904/5045/5594/6774/6714/5519/5598/1432/4914/6195/4803/5603/2002/1398/1385/6196/1759/5518/1213/387/1211/8851/581/6197/3845/5600/3265/6300/1020/51231/7529/5595/5515/25920/5516/5607 40 Cottontail_rabbit_papillomavirus R-HSA-209560 NF-kB is activated and signals survival 12/1598 13/10654 1.4032926482451397e-9 6.1547097022026766e-9 2.9493434323767507e-9 4804/4790/8878/7316/5970/4792/4803/7189/6233/7311/3551/7314 12 Cottontail_rabbit_papillomavirus R-HSA-111447 Activation of BAD and translocation to mitochondria 13/1598 15/10654 1.4544541129604504e-9 6.35776429979702e-9 3.046647411411611e-9 596/7531/7532/207/10971/7533/2810/7534/10000/5534/208/637/7529 13 Cottontail_rabbit_papillomavirus R-HSA-186712 Regulation of beta-cell development 23/1598 42/10654 2.3986568074668348e-9 1.0450148157863843e-8 5.007722106816725e-9 2308/2648/3172/3171/207/55534/3280/6927/84441/10046/50674/22938/8850/1387/10000/2033/3630/6514/208/9794/5080/3516/4851 23 Cottontail_rabbit_papillomavirus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 31/1598 69/10654 2.5675590476061255e-9 1.114883613030301e-8 5.3425341259858175e-9 3303/6118/5903/573/9631/7531/5594/3308/10049/545/472/3337/3313/3305/9532/4927/6119/2932/57805/3310/3309/7266/3306/23411/9529/6117/6396/3304/3312/8480/5595 31 Cottontail_rabbit_papillomavirus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 17/1598 25/10654 2.9575886749408846e-9 1.2799895358105086e-8 6.1337234631921445e-9 1147/2308/2309/842/207/4303/1027/7249/6199/1026/2932/3164/10000/208/2475/1385/4193 17 Cottontail_rabbit_papillomavirus R-HSA-176187 Activation of ATR in response to replication stress 21/1598 37/10654 5.01192738769455e-9 2.1619105926458006e-8 1.035989854326301e-8 1017/4172/6118/5883/5982/63967/545/4174/84515/6119/3364/144715/5985/995/84126/1111/5984/5983/6117/5884/5810 21 Cottontail_rabbit_papillomavirus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 16/1598 23/10654 5.260068514600956e-9 2.2614834041392926e-8 1.0837052514499892e-8 7321/6497/64750/7316/9611/9612/4089/23327/4088/142/3065/6498/4087/6233/7311/7314 16 Cottontail_rabbit_papillomavirus R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 10/1598 10/10654 5.626283373757831e-9 2.3875170030848978e-8 1.1441006860512337e-8 5563/51422/53632/1432/5571/5600/5564/6300/5565/10891 10 Cottontail_rabbit_papillomavirus R-HSA-390450 Folding of actin by CCT/TriC 10/1598 10/10654 5.626283373757831e-9 2.3875170030848978e-8 1.1441006860512337e-8 10694/10575/7203/10576/908/6950/10574/60/22948/10693 10 Cottontail_rabbit_papillomavirus R-HSA-450341 Activation of the AP-1 family of transcription factors 10/1598 10/10654 5.626283373757831e-9 2.3875170030848978e-8 1.1441006860512337e-8 3725/5601/5594/1432/5602/2353/1386/5599/5600/5595 10 Cottontail_rabbit_papillomavirus R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 10/1598 10/10654 5.626283373757831e-9 2.3875170030848978e-8 1.1441006860512337e-8 2308/2309/4303/23410/7295/8850/1387/10628/2033/23411 10 Cottontail_rabbit_papillomavirus R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 13/1598 16/10654 6.685781532021109e-9 2.8279341302108704e-8 1.3551490415781161e-8 2648/55534/3280/84441/10046/50674/22938/8850/1387/2033/9794/3516/4851 13 Cottontail_rabbit_papillomavirus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 17/1598 26/10654 7.349045225456058e-9 3.0984522934422795e-8 1.4847816329868778e-8 57154/10273/64750/7316/5501/4092/23327/7046/4088/9958/4087/5499/6233/7514/7311/7040/7314 17 Cottontail_rabbit_papillomavirus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 26/1598 54/10654 8.15892143272498e-9 3.428845759669308e-8 1.6431065332446652e-8 9318/5434/902/2074/27339/5430/8450/7316/9978/4331/1161/1642/2965/2033/2068/10987/2071/6233/2873/2968/7311/7874/1022/7314/51138/8451 26 Cottontail_rabbit_papillomavirus R-HSA-3371568 Attenuation phase 12/1598 14/10654 8.472876863450526e-9 3.549375019400589e-8 1.7008642826427338e-8 3303/3337/3305/1387/3320/2033/3326/3306/3304/3312/2288/10728 12 Cottontail_rabbit_papillomavirus R-HSA-5689896 Ovarian tumor domain proteases 21/1598 38/10654 9.624455167621085e-9 4.0189018862877826e-8 1.925862056409802e-8 7321/55611/7706/8517/7316/79155/983/2099/79589/7415/7128/324/5728/7157/7189/6233/7311/55593/78990/387/7314 21 Cottontail_rabbit_papillomavirus R-HSA-2871796 FCERI mediated MAPK activation 19/1598 32/10654 9.769023036776148e-9 4.0533692409734684e-8 1.94237884941748e-8 3725/5601/4893/2205/5336/5594/4214/2206/6850/4067/5602/5609/7409/2353/3845/5599/3265/2207/5595 19 Cottontail_rabbit_papillomavirus R-HSA-5656169 Termination of translesion DNA synthesis 19/1598 32/10654 9.769023036776148e-9 4.0533692409734684e-8 1.94237884941748e-8 6118/5982/7706/7316/11201/5111/9100/6119/51455/5985/5984/6233/51426/7311/5983/6117/5981/10714/7314 19 Cottontail_rabbit_papillomavirus R-HSA-212165 Epigenetic regulation of gene expression 50/1598 149/10654 9.997780893839226e-9 4.135158110205022e-8 1.9815721625031115e-8 8467/23451/5252/5434/902/9015/10514/2648/2074/2146/29128/1788/9112/9219/1786/6839/9014/5931/51082/8819/6996/4331/9013/23309/4641/1108/8850/5928/2932/29947/57459/2965/54815/2033/23512/2068/3066/3065/2071/1107/2968/57504/6908/23411/60/25942/8726/53615/1022/10919 50 Cottontail_rabbit_papillomavirus R-HSA-187037 Signaling by NTRK1 (TRKA) 33/1598 80/10654 1.1125795122476842e-8 4.587196916428149e-8 2.198189639008375e-8 4893/5290/5604/5594/6774/6714/5519/5598/1432/4914/6195/4803/5603/2002/1398/1385/6196/1759/5518/1213/387/1211/6197/3845/5600/3265/6300/51231/7529/5595/5515/5516/5607 33 Cottontail_rabbit_papillomavirus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 21/1598 39/10654 1.7915505714514174e-8 7.363385524801894e-8 3.5285421715113984e-8 6118/5982/7706/7316/11201/5111/9100/7415/6119/51455/5985/25898/5984/6233/51426/7311/5983/6117/5981/10714/7314 21 Cottontail_rabbit_papillomavirus R-HSA-168638 NOD1/2 Signaling Pathway 20/1598 36/10654 1.9270662811788772e-8 7.895534888717217e-8 3.783548712428418e-8 1147/834/842/841/8517/7316/7128/1432/5603/10454/83737/7189/6233/7311/5600/7334/1540/3551/6300/7314 20 Cottontail_rabbit_papillomavirus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 32/1598 78/10654 2.1698958828947928e-8 8.862668496698419e-8 4.2470001655342164e-8 1147/3665/351/4790/7321/4214/841/7706/8517/7316/5970/4792/4793/3093/3146/7128/1387/843/2033/54941/83737/7189/6285/51191/6233/7311/55593/5300/1540/3551/3456/7314 32 Cottontail_rabbit_papillomavirus R-HSA-4655427 SUMOylation of DNA methylation proteins 13/1598 17/10654 2.4493342022623247e-8 9.94186274023869e-8 4.764151194331753e-8 1912/1788/8535/1786/6045/80012/1911/7341/84733/57332/7329/648/6015 13 Cottontail_rabbit_papillomavirus R-HSA-8934593 Regulation of RUNX1 Expression and Activity 13/1598 17/10654 2.4493342022623247e-8 9.94186274023869e-8 4.764151194331753e-8 27161/57690/27327/192670/6714/1021/595/192669/861/5371/23112/4343/26523 13 Cottontail_rabbit_papillomavirus R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 16/1598 25/10654 3.246251388064615e-8 1.3135760260682511e-7 6.294670281565736e-8 6118/7515/5982/7316/5111/6119/5985/5984/6233/51426/7311/5983/6117/5981/10714/7314 16 Cottontail_rabbit_papillomavirus R-HSA-8848021 Signaling by PTK6 25/1598 54/10654 4.267418066948681e-8 1.7161585887698232e-7 8.223850201893004e-8 120892/1017/1019/4893/207/27043/1027/898/3091/2064/7316/1950/6774/867/2908/595/2066/6233/1398/7311/387/1956/3845/3265/7314 25 Cottontail_rabbit_papillomavirus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 25/1598 54/10654 4.267418066948681e-8 1.7161585887698232e-7 8.223850201893004e-8 120892/1017/1019/4893/207/27043/1027/898/3091/2064/7316/1950/6774/867/2908/595/2066/6233/1398/7311/387/1956/3845/3265/7314 25 Cottontail_rabbit_papillomavirus R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 39/1598 110/10654 7.883299990706999e-8 3.1605745668263954e-7 1.514550692434829e-7 1017/3725/1019/4790/1029/7321/8697/5594/1027/1051/79813/3576/3490/7316/890/6774/5970/1026/51433/1031/5598/3552/1021/6195/8900/64682/6233/51434/2353/1030/51343/6196/7311/6197/3569/10919/7314/996/5595 39 Cottontail_rabbit_papillomavirus R-HSA-193639 p75NTR signals via NF-kB 12/1598 16/10654 1.2612892686558088e-7 5.041299920896459e-7 2.415796281507183e-7 4804/4790/8878/7316/5970/4792/4803/7189/6233/7311/3551/7314 12 Cottontail_rabbit_papillomavirus R-HSA-5693568 Resolution of D-loop Structures through Holliday Junction Intermediates 18/1598 33/10654 1.4601405770413385e-7 5.818304067661675e-7 2.788137494671362e-7 80010/83990/5888/9156/1763/7486/10111/675/472/580/116028/641/10524/4683/79728/672/5932/7156 18 Cottontail_rabbit_papillomavirus R-HSA-1538133 G0 and Early G1 16/1598 27/10654 1.534814726156108e-7 6.097273091446909e-7 2.921819747441639e-7 1017/9134/7027/7153/898/5934/1869/890/983/5933/5111/4609/5928/1874/3065/8900 16 Cottontail_rabbit_papillomavirus R-HSA-4090294 SUMOylation of intracellular receptors 17/1598 30/10654 1.5429605620581785e-7 6.111058953363755e-7 2.9284259471279623e-7 7068/5241/5468/51588/6613/4929/9759/8856/2099/7341/2908/7329/367/6612/9063/7421/8554 17 Cottontail_rabbit_papillomavirus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 33/1598 88/10654 1.7198331056183266e-7 6.791002625508015e-7 3.2542556776686417e-7 8454/115106/8945/22995/22981/7531/4659/203068/7532/1454/6500/7277/7316/891/983/6790/5566/23291/7846/7283/3320/10540/6233/7311/54930/5518/10383/55835/5347/9662/1453/8481/7314 33 Cottontail_rabbit_papillomavirus R-HSA-198323 AKT phosphorylates targets in the cytosol 11/1598 14/10654 1.9669220405995969e-7 7.743274418866485e-7 3.71058533340761e-7 1147/842/207/1027/7249/1026/2932/10000/208/23608/4193 11 Cottontail_rabbit_papillomavirus R-HSA-2219528 PI3K/AKT Signaling in Cancer 36/1598 101/10654 2.124083450965108e-7 8.336868079313502e-7 3.9950360465441416e-7 1147/2308/5290/2309/842/3815/207/4303/1027/7249/2064/6199/2100/1950/2263/4233/1026/6714/2099/2932/2261/5159/2247/3164/10000/5728/2264/2066/208/2475/7409/1385/3932/1956/5156/4193 36 Cottontail_rabbit_papillomavirus R-HSA-5693537 Resolution of D-Loop Structures 18/1598 34/10654 2.668874919090171e-7 1.0443771015721118e-6 5.004666173522382e-7 80010/83990/5888/9156/1763/7486/10111/675/472/580/116028/641/10524/4683/79728/672/5932/7156 18 Cottontail_rabbit_papillomavirus R-HSA-198753 ERK/MAPK targets 14/1598 22/10654 2.6926296695160623e-7 1.0505274561365652e-6 5.034138737979755e-7 5594/5519/5598/1432/6195/2002/6196/5518/6197/5600/51231/5595/5515/5516 14 Cottontail_rabbit_papillomavirus R-HSA-2197563 NOTCH2 intracellular domain regulates transcription 10/1598 12/10654 2.774911345895618e-7 1.0730204523921813e-6 5.141925415160053e-7 55534/3280/84441/10046/2033/4853/9794/1385/388585/3516 10 Cottontail_rabbit_papillomavirus R-HSA-3371511 HSF1 activation 10/1598 12/10654 2.774911345895618e-7 1.0730204523921813e-6 5.141925415160053e-7 6118/7531/1915/10013/7415/6119/3320/3326/6117/10728 10 Cottontail_rabbit_papillomavirus R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 10/1598 12/10654 2.774911345895618e-7 1.0730204523921813e-6 5.141925415160053e-7 834/58484/55367/472/843/7157/8626/7161/839/317 10 Cottontail_rabbit_papillomavirus R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 17/1598 31/10654 2.939880313025429e-7 1.1334582799776507e-6 5.431544127465084e-7 857/1499/1856/1452/7471/89780/5519/2932/1455/324/8312/5527/1855/1857/5518/5515/5516 17 Cottontail_rabbit_papillomavirus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 15/1598 25/10654 3.022601723377666e-7 1.1585162617168944e-6 5.551622242351324e-7 5594/5519/5598/1432/6195/2002/1385/6196/5518/6197/5600/51231/5595/5515/5516 15 Cottontail_rabbit_papillomavirus R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 15/1598 25/10654 3.022601723377666e-7 1.1585162617168944e-6 5.551622242351324e-7 10694/51807/10575/7277/7203/10576/908/6950/7846/10574/10383/84790/22948/10693/7280 15 Cottontail_rabbit_papillomavirus R-HSA-194138 Signaling by VEGF 37/1598 107/10654 3.4904192793293417e-7 1.3339116953460378e-6 6.392119024933698e-7 5590/4893/857/5290/5579/1499/5747/5567/207/7422/5578/5568/3315/6714/5566/1432/2321/10000/3320/4846/5603/998/208/1398/5580/2324/2475/7409/6093/3791/387/60/3845/5600/3265/6300/3071 37 Cottontail_rabbit_papillomavirus R-HSA-4420097 VEGFA-VEGFR2 Pathway 35/1598 99/10654 3.920421231885931e-7 1.4938747959402074e-6 7.158663903551109e-7 5590/4893/857/5290/5579/1499/5747/5567/207/7422/5578/5568/3315/6714/5566/1432/10000/3320/4846/5603/998/208/1398/5580/2475/7409/6093/3791/387/60/3845/5600/3265/6300/3071 35 Cottontail_rabbit_papillomavirus R-HSA-5696394 DNA Damage Recognition in GG-NER 19/1598 38/10654 4.0147277901087816e-7 1.5209418033832399e-6 7.288369290967888e-7 9318/86/8450/7316/9978/1643/1642/142/10987/6233/2873/7311/60/5886/7508/7314/51138/8451/7528 19 Cottontail_rabbit_papillomavirus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 19/1598 38/10654 4.0147277901087816e-7 1.5209418033832399e-6 7.288369290967888e-7 7020/7021/3815/7422/4869/51741/2064/1026/2099/4609/10370/7341/1387/2033/7022/7329/1956/8089/7528 19 Cottontail_rabbit_papillomavirus R-HSA-1592230 Mitochondrial biogenesis 34/1598 95/10654 4.110485528940861e-7 1.5527180885334408e-6 7.44064158722182e-7 5563/5442/8841/79718/23408/23410/51422/200186/53632/3313/9611/5469/23409/54205/1432/5571/1387/6907/6648/10498/1385/10499/23054/1386/5600/3054/5564/6300/23373/5565/7019/8648/814/10891 34 Cottontail_rabbit_papillomavirus R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 24/1598 56/10654 4.7552348364435426e-7 1.791092775571098e-6 8.58293562167119e-7 5442/8841/79718/23408/23410/200186/9611/5469/23409/54205/1387/6907/6648/10498/1385/10499/23054/1386/3054/23373/7019/8648/814/10891 24 Cottontail_rabbit_papillomavirus R-HSA-1251985 Nuclear signaling by ERBB4 17/1598 32/10654 5.397186159055231e-7 2.0154635171100534e-6 9.658122600414624e-7 5241/51741/23385/6776/9611/6714/2099/5664/2066/6868/3925/6285/83464/55851/51107/5663/6387 17 Cottontail_rabbit_papillomavirus R-HSA-381042 PERK regulates gene expression 17/1598 32/10654 5.397186159055231e-7 2.0154635171100534e-6 9.658122600414624e-7 4802/1051/1649/3576/468/4800/1054/8894/3309/4801/9451/6347/11340/467/8570/23016/54512 17 Cottontail_rabbit_papillomavirus R-HSA-8941326 RUNX2 regulates bone development 17/1598 32/10654 5.397186159055231e-7 2.0154635171100534e-6 9.658122600414624e-7 25/8841/23462/5594/3280/4086/5925/10013/4094/9759/6714/4089/23493/25937/367/860/5595 17 Cottontail_rabbit_papillomavirus R-HSA-937039 IRAK1 recruits IKK complex 11/1598 15/10654 6.370927035949677e-7 2.3655686465869966e-6 1.1335830102841082e-6 1147/8517/7316/57162/7189/6233/7311/7334/3551/57161/7314 11 Cottontail_rabbit_papillomavirus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 11/1598 15/10654 6.370927035949677e-7 2.3655686465869966e-6 1.1335830102841082e-6 1147/8517/7316/57162/7189/6233/7311/7334/3551/57161/7314 11 Cottontail_rabbit_papillomavirus R-HSA-193704 p75 NTR receptor-mediated signalling 34/1598 97/10654 7.210317823924243e-7 2.6696559195096274e-6 1.2793019547442746e-6 9181/4804/8841/4790/10018/7531/29/8878/1894/23385/9500/7316/9828/5970/4792/5664/836/4803/3066/3065/7189/6868/83464/6233/7409/7311/26574/387/5599/55851/51107/3551/5663/7314 34 Cottontail_rabbit_papillomavirus R-HSA-438064 Post NMDA receptor activation events 30/1598 81/10654 8.450767904109135e-7 3.1200999013193894e-6 1.4951551896951935e-6 5563/3838/4893/2904/5567/51807/5594/5568/51422/7277/53632/6714/5566/5571/7846/6195/2066/1385/6196/5562/10383/84790/6197/3845/3265/5564/5565/814/7280/5595 30 Cottontail_rabbit_papillomavirus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 17/1598 33/10654 9.580297089944994e-7 3.517623478544039e-6 1.6856489105091638e-6 1147/351/4790/8517/7316/5970/4792/4793/3146/10454/7189/6285/6233/7311/7334/3551/7314 17 Cottontail_rabbit_papillomavirus R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 12/1598 18/10654 9.581285067801667e-7 3.517623478544039e-6 1.6856489105091638e-6 4893/5578/5594/5598/6195/1385/6196/1956/6197/3845/3265/5595 12 Cottontail_rabbit_papillomavirus R-HSA-5675221 Negative regulation of MAPK pathway 19/1598 40/10654 1.1029062358253005e-6 4.037810784940245e-6 1.9349232207461414e-6 4893/1844/5604/5594/7316/5519/6233/5527/7311/5518/1843/3845/3265/369/7529/7314/5595/5515/5516 19 Cottontail_rabbit_papillomavirus R-HSA-3371571 HSF1-dependent transactivation 14/1598 24/10654 1.2267259368844022e-6 4.466102505593074e-6 2.1401610686005553e-6 3303/1410/3337/3305/1387/3320/2033/3326/2475/3306/3304/3312/2288/10728 14 Cottontail_rabbit_papillomavirus R-HSA-8940973 RUNX2 regulates osteoblast differentiation 14/1598 24/10654 1.2267259368844022e-6 4.466102505593074e-6 2.1401610686005553e-6 25/8841/23462/5594/3280/5925/10013/4094/6714/23493/25937/367/860/5595 14 Cottontail_rabbit_papillomavirus R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 18/1598 37/10654 1.3625698975552342e-6 4.946885711401919e-6 2.37055289194551e-6 27161/8841/79718/57690/27327/192670/9611/2874/9612/6907/2033/192669/23028/23112/4343/1071/26523/8648 18 Cottontail_rabbit_papillomavirus R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 23/1598 55/10654 1.3873688130411223e-6 5.02296686605193e-6 2.407011062135786e-6 3303/5241/51807/10294/7277/3337/3305/832/7846/2908/3320/3301/10540/3326/3306/367/10383/84790/3304/3312/7280/2288/10728 23 Cottontail_rabbit_papillomavirus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 25/1598 63/10654 1.5727129332096214e-6 5.678275700842473e-6 2.721035752427231e-6 1147/3665/5434/4790/1499/7520/23220/51082/8517/6778/7098/5591/7316/5970/4792/4793/3428/1387/2033/22954/6233/7311/3551/2547/7314 25 Cottontail_rabbit_papillomavirus R-HSA-1295596 Spry regulation of FGF signaling 11/1598 16/10654 1.7612130123996161e-6 6.341337209934706e-6 3.038775532485926e-6 5594/7316/6714/867/6233/7311/5518/7314/5595/5515/5516 11 Cottontail_rabbit_papillomavirus R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 15/1598 28/10654 2.213254739949852e-6 7.92527108250536e-6 3.797798328104288e-6 10694/10575/7277/7203/10576/908/6950/7846/10574/10383/60/84790/22948/10693/7280 15 Cottontail_rabbit_papillomavirus R-HSA-69205 G1/S-Specific Transcription 15/1598 28/10654 2.213254739949852e-6 7.92527108250536e-6 3.797798328104288e-6 7027/898/5934/5422/1869/983/5933/5111/5928/1874/3065/8900/1719/7083/6241 15 Cottontail_rabbit_papillomavirus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 27/1598 72/10654 2.2401406247487775e-6 7.97279623274991e-6 3.820572430625536e-6 5563/7531/11127/4627/51807/7532/207/10971/51422/7533/2810/7277/53632/7534/4641/5571/7846/208/5867/9882/10383/60/84790/5564/5565/7280/7529 27 Cottontail_rabbit_papillomavirus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 12/1598 19/10654 2.2448270953725838e-6 7.97279623274991e-6 3.820572430625536e-6 4893/5290/7316/1950/867/3320/6233/7311/1956/3845/3265/7314 12 Cottontail_rabbit_papillomavirus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 12/1598 19/10654 2.2448270953725838e-6 7.97279623274991e-6 3.820572430625536e-6 4893/5290/7316/1950/867/3320/6233/7311/1956/3845/3265/7314 12 Cottontail_rabbit_papillomavirus R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 38/1598 119/10654 2.326906537361914e-6 8.24191556729545e-6 3.949534701840932e-6 8841/79718/5468/892/9440/4802/6721/1543/6720/6837/9611/5469/2874/81857/4800/9612/1024/6667/23309/1387/6907/9439/2033/9967/4801/10498/183/2274/112950/10499/23054/25942/9412/405/8202/8648/10891/7296 38 Cottontail_rabbit_papillomavirus R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 13/1598 22/10654 2.4410223221292944e-6 8.576387567266097e-6 4.109814039804556e-6 4000/3725/351/2309/10018/7531/823/2801/995/6648/8851/5052/1020 13 Cottontail_rabbit_papillomavirus R-HSA-8863678 Neurodegenerative Diseases 13/1598 22/10654 2.4410223221292944e-6 8.576387567266097e-6 4.109814039804556e-6 4000/3725/351/2309/10018/7531/823/2801/995/6648/8851/5052/1020 13 Cottontail_rabbit_papillomavirus R-HSA-9613829 Chaperone Mediated Autophagy 13/1598 22/10654 2.4410223221292944e-6 8.576387567266097e-6 4.109814039804556e-6 1915/1080/10013/7316/3043/3320/6233/3326/7311/7431/3312/11315/7314 13 Cottontail_rabbit_papillomavirus R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 10/1598 14/10654 3.1474864830602653e-6 1.0970039555626044e-5 5.256854617321706e-6 6118/4436/9156/2956/4292/5111/5395/6119/6117/10714 10 Cottontail_rabbit_papillomavirus R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 10/1598 14/10654 3.1474864830602653e-6 1.0970039555626044e-5 5.256854617321706e-6 8841/79718/9611/2874/9612/5566/6907/3065/25942/814 10 Cottontail_rabbit_papillomavirus R-HSA-9005895 Pervasive developmental disorders 10/1598 14/10654 3.1474864830602653e-6 1.0970039555626044e-5 5.256854617321706e-6 8841/79718/9611/2874/9612/5566/6907/3065/25942/814 10 Cottontail_rabbit_papillomavirus R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 16/1598 32/10654 3.3483788123600544e-6 1.163917847807072e-5 5.5775067003198e-6 10694/51807/10575/7277/7203/10576/908/6950/7846/10574/10383/60/84790/22948/10693/7280 16 Cottontail_rabbit_papillomavirus R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 18/1598 39/10654 3.559818562455182e-6 1.2341333849148336e-5 5.913980300602634e-6 10694/9134/8841/8237/10575/898/7203/10576/908/6774/26272/6950/55294/10238/7157/10574/22948/10693 18 Cottontail_rabbit_papillomavirus R-HSA-1227986 Signaling by ERBB2 21/1598 50/10654 3.6552140850463703e-6 1.2638531241152397e-5 6.056397606801979e-6 4893/5290/10273/207/5578/2064/7316/1950/6714/10000/3320/2066/208/6233/5580/7311/387/1956/3845/3265/7314 21 Cottontail_rabbit_papillomavirus R-HSA-1433557 Signaling by SCF-KIT 19/1598 43/10654 4.2799659869537106e-6 1.4759671622555407e-5 7.072850332557861e-6 4893/5290/3815/5578/4318/6776/6774/6772/6714/8651/867/4067/3717/1111/7409/3932/3845/6777/3265 19 Cottontail_rabbit_papillomavirus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 13/1598 23/10654 4.843418762326851e-6 1.6577029332806106e-5 7.943730079345737e-6 7321/991/8697/7316/891/983/51433/64682/6233/51434/7311/7314/996 13 Cottontail_rabbit_papillomavirus R-HSA-69186 Lagging Strand Synthesis 12/1598 20/10654 4.845007808058097e-6 1.6577029332806106e-5 7.943730079345737e-6 6118/1763/5982/5422/5111/6119/5985/5984/5983/6117/5981/10714 12 Cottontail_rabbit_papillomavirus R-HSA-8876384 Listeria monocytogenes entry into host cells 12/1598 20/10654 4.845007808058097e-6 1.6577029332806106e-5 7.943730079345737e-6 1499/2060/7316/4233/6714/867/999/9146/6233/7311/10254/7314 12 Cottontail_rabbit_papillomavirus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 15/1598 30/10654 6.80805087694112e-6 2.3232695812433533e-5 1.1133132532032339e-5 7124/1147/27005/8517/7316/7128/9099/10616/10454/6233/7311/331/1540/3551/7314 15 Cottontail_rabbit_papillomavirus R-HSA-1912408 Pre-NOTCH Transcription and Translation 31/1598 93/10654 7.3021177473795276e-6 2.4853822645377716e-5 1.1909978233801586e-5 1999/27161/3725/2648/7027/55534/57690/27327/84441/51548/10046/192670/1869/4854/1871/22938/8850/1387/2033/4855/595/4853/192669/7157/861/23112/9794/4343/26523/3516/4851 31 Cottontail_rabbit_papillomavirus R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress 14/1598 27/10654 8.039351489244107e-6 2.723452595122976e-5 1.3050813788895187e-5 4802/1051/1649/3576/468/4800/1054/4801/6347/11340/467/8570/23016/54512 14 Cottontail_rabbit_papillomavirus R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 10/1598 15/10654 8.168274041990869e-6 2.723452595122976e-5 1.3050813788895187e-5 1499/1452/5519/2932/324/8312/5527/5518/5515/5516 10 Cottontail_rabbit_papillomavirus R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 10/1598 15/10654 8.168274041990869e-6 2.723452595122976e-5 1.3050813788895187e-5 1499/1452/5519/2932/324/8312/5527/5518/5515/5516 10 Cottontail_rabbit_papillomavirus R-HSA-5358508 Mismatch Repair 10/1598 15/10654 8.168274041990869e-6 2.723452595122976e-5 1.3050813788895187e-5 6118/4436/9156/2956/4292/5111/5395/6119/6117/10714 10 Cottontail_rabbit_papillomavirus R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 10/1598 15/10654 8.168274041990869e-6 2.723452595122976e-5 1.3050813788895187e-5 1499/1452/5519/2932/324/8312/5527/5518/5515/5516 10 Cottontail_rabbit_papillomavirus R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 10/1598 15/10654 8.168274041990869e-6 2.723452595122976e-5 1.3050813788895187e-5 1499/1452/5519/2932/324/8312/5527/5518/5515/5516 10 Cottontail_rabbit_papillomavirus R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 10/1598 15/10654 8.168274041990869e-6 2.723452595122976e-5 1.3050813788895187e-5 1499/1452/5519/2932/324/8312/5527/5518/5515/5516 10 Cottontail_rabbit_papillomavirus R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 10/1598 15/10654 8.168274041990869e-6 2.723452595122976e-5 1.3050813788895187e-5 1499/1452/5519/2932/324/8312/5527/5518/5515/5516 10 Cottontail_rabbit_papillomavirus R-HSA-381183 ATF6 (ATF6-alpha) activates chaperone genes 8/1598 10/10654 8.543745294496196e-6 2.8413931551925005e-5 1.3615986206576235e-5 4802/7184/7494/1649/468/4800/3309/4801 8 Cottontail_rabbit_papillomavirus R-HSA-933542 TRAF6 mediated NF-kB activation 13/1598 24/10654 9.117692101486084e-6 3.02457451183815e-5 1.4493793215025969e-5 1147/351/4790/4214/7706/8517/5970/4792/4793/3146/7189/6285/3551 13 Cottontail_rabbit_papillomavirus R-HSA-5693606 DNA Double Strand Break Response 27/1598 77/10654 9.754873374672439e-6 3.227751772328323e-5 1.5467420807275418e-5 8467/25/3838/322/10111/51588/51720/11200/472/7336/580/7316/9656/7341/10524/4683/7157/7329/8924/6233/672/7158/7311/79184/5599/7334/7314 27 Cottontail_rabbit_papillomavirus R-HSA-5654738 Signaling by FGFR2 26/1598 73/10654 1.0284433051367334e-5 3.394382322761895e-5 1.6265916176405006e-5 2963/5434/4893/5290/5430/5594/3178/7316/3185/2263/6714/2962/867/4670/2247/6233/3187/7311/5518/3845/3265/5725/7314/5595/5515/5516 26 Cottontail_rabbit_papillomavirus R-HSA-177929 Signaling by EGFR 20/1598 49/10654 1.0458448162835372e-5 3.443121347311292e-5 1.6499474100191027e-5 4893/5290/2060/7316/1950/102/6714/867/9146/1445/998/6868/6233/7311/1956/29924/3845/3265/10254/7314 20 Cottontail_rabbit_papillomavirus R-HSA-1989781 PPARA activates gene expression 36/1598 117/10654 1.092538750807403e-5 3.587809415339888e-5 1.719282086036511e-5 8841/79718/5468/892/9440/4802/6721/1543/6720/6837/9611/5469/2874/81857/4800/9612/1024/6667/1387/6907/9439/2033/9967/4801/10498/183/2274/112950/10499/23054/9412/405/8202/8648/10891/7296 36 Cottontail_rabbit_papillomavirus R-HSA-68877 Mitotic Prometaphase 53/1598 200/10654 1.4960601164829992e-5 4.9006280006097245e-5 2.3483861477572474e-5 10844/115106/11130/22995/5903/22981/7531/1459/55869/1058/991/203068/51807/7532/1454/9212/79172/1460/23244/7277/6232/332/891/5501/1457/983/5566/3796/5519/699/7846/7283/3320/80097/8243/9126/10540/5527/701/7514/54930/5518/10383/55835/5347/84790/6396/9662/1453/8481/7280/5515/5516 53 Cottontail_rabbit_papillomavirus R-HSA-209543 p75NTR recruits signalling complexes 9/1598 13/10654 1.5154404496865318e-5 4.951701669350743e-5 2.372860704114438e-5 4804/8878/7316/4803/7189/6233/7311/3551/7314 9 Cottontail_rabbit_papillomavirus R-HSA-429947 Deadenylation of mRNA 13/1598 25/10654 1.6391596589293323e-5 5.342597691323285e-5 2.560178493405835e-5 9924/4849/4850/26986/9337/25904/246175/4848/23019/55571/57472/85456/29883 13 Cottontail_rabbit_papillomavirus R-HSA-2682334 EPH-Ephrin signaling 30/1598 92/10654 1.665375139831235e-5 5.414540566565732e-5 2.594653595704595e-5 2042/2904/5747/4627/1212/3985/23385/4318/6383/4313/10398/102/6714/5664/4067/998/1948/2048/83464/6093/1759/1213/387/1211/60/55851/51107/3265/5663/1969 30 Cottontail_rabbit_papillomavirus R-HSA-73933 Resolution of Abasic Sites (AP sites) 17/1598 39/10654 1.705651910437811e-5 5.531729645017912e-5 2.6508107266827674e-5 6118/328/4913/7515/5982/6996/5111/6119/5985/142/5984/4595/4968/5983/6117/5981/10714 17 Cottontail_rabbit_papillomavirus R-HSA-69190 DNA strand elongation 15/1598 32/10654 1.8444235927115563e-5 5.966984246717832e-5 2.8593851945371968e-5 4172/6118/1763/5982/5422/4174/84515/5111/6119/5985/5984/5983/6117/5981/10714 15 Cottontail_rabbit_papillomavirus R-HSA-4551638 SUMOylation of chromatin organization proteins 25/1598 71/10654 1.9019873511606748e-5 6.138018439424697e-5 2.9413449615090362e-5 1912/5903/9631/8535/6045/80012/6613/9759/1911/4927/7341/84733/23512/57332/3066/3065/1107/7329/6612/9063/6396/648/8480/6015/8554 25 Cottontail_rabbit_papillomavirus R-HSA-9024446 NR1H2 and NR1H3-mediated signaling 19/1598 47/10654 2.043482622170504e-5 6.578403416691746e-5 3.152377910789344e-5 27161/8841/79718/57690/27327/6720/192670/9611/2874/9612/6907/2033/192669/23028/23112/4343/1071/26523/8648 19 Cottontail_rabbit_papillomavirus R-HSA-442755 Activation of NMDA receptors and postsynaptic events 30/1598 93/10654 2.1106910279708904e-5 6.778066765498657e-5 3.248056799800026e-5 5563/3838/4893/2904/5567/51807/5594/5568/51422/7277/53632/6714/5566/5571/7846/6195/2066/1385/6196/5562/10383/84790/6197/3845/3265/5564/5565/814/7280/5595 30 Cottontail_rabbit_papillomavirus R-HSA-3928665 EPH-ephrin mediated repulsion of cells 20/1598 51/10654 2.122063946068862e-5 6.797886219392164e-5 3.257554303175885e-5 2042/1212/23385/4318/4313/102/6714/5664/4067/1948/2048/83464/1759/1213/1211/60/55851/51107/5663/1969 20 Cottontail_rabbit_papillomavirus R-HSA-5693565 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 26/1598 76/10654 2.3385293901376818e-5 7.473002232053668e-5 3.581070614160136e-5 8467/25/322/10111/51588/51720/11200/472/7336/580/7316/9656/7341/10524/4683/7157/7329/8924/6233/672/7158/7311/79184/5599/7334/7314 26 Cottontail_rabbit_papillomavirus R-HSA-5654741 Signaling by FGFR3 17/1598 40/10654 2.5546540508983995e-5 8.143738645180996e-5 3.90248821639165e-5 4893/5290/5594/7316/6714/2261/867/2247/6233/7311/5518/3845/3265/7314/5595/5515/5516 17 Cottontail_rabbit_papillomavirus R-HSA-4755510 SUMOylation of immune response proteins 8/1598 11/10654 2.7183591270054097e-5 8.644514304126692e-5 4.142460444533791e-5 51588/8517/10210/5970/4792/7341/7329/6612 8 Cottontail_rabbit_papillomavirus R-HSA-5357905 Regulation of TNFR1 signaling 15/1598 33/10654 2.914933324559567e-5 9.247130716503287e-5 4.431234869987079e-5 7124/1147/841/27005/8517/7316/7128/9099/10616/6233/7311/331/1540/3551/7314 15 Cottontail_rabbit_papillomavirus R-HSA-383280 Nuclear Receptor transcription pathway 20/1598 52/10654 2.9667527201333468e-5 9.388730763230712e-5 4.499089762914085e-5 7068/5241/7025/5468/3172/6097/2100/4929/9611/5469/2063/9612/8856/2099/7101/2908/3164/367/8431/7421 20 Cottontail_rabbit_papillomavirus R-HSA-390466 Chaperonin-mediated protein folding 30/1598 95/10654 3.340258623240408e-5 1.0545212610085057e-4 5.0532770933842945e-5 10694/9134/8841/1459/51807/8237/10575/898/1460/7277/7203/10576/908/6774/1457/26272/6950/7846/55294/2783/10238/7157/10574/10383/60/84790/22948/10693/2791/7280 30 Cottontail_rabbit_papillomavirus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 12/1598 23/10654 3.349398614479986e-5 1.0548587925603233e-4 5.054894548168907e-5 5601/8517/7316/5602/10454/7189/5609/6233/7311/5599/7334/7314 12 Cottontail_rabbit_papillomavirus R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 9/1598 14/10654 3.6766856921714455e-5 1.1387270615327203e-4 5.456792184689474e-5 1452/5519/2932/324/8312/5527/5518/5515/5516 9 Cottontail_rabbit_papillomavirus R-HSA-4839744 truncated APC mutants destabilize the destruction complex 9/1598 14/10654 3.6766856921714455e-5 1.1387270615327203e-4 5.456792184689474e-5 1452/5519/2932/324/8312/5527/5518/5515/5516 9 Cottontail_rabbit_papillomavirus R-HSA-4839748 AMER1 mutants destabilize the destruction complex 9/1598 14/10654 3.6766856921714455e-5 1.1387270615327203e-4 5.456792184689474e-5 1452/5519/2932/324/8312/5527/5518/5515/5516 9 Cottontail_rabbit_papillomavirus R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 9/1598 14/10654 3.6766856921714455e-5 1.1387270615327203e-4 5.456792184689474e-5 6118/4436/9156/4292/5111/5395/6119/6117/10714 9 Cottontail_rabbit_papillomavirus R-HSA-5467337 APC truncation mutants have impaired AXIN binding 9/1598 14/10654 3.6766856921714455e-5 1.1387270615327203e-4 5.456792184689474e-5 1452/5519/2932/324/8312/5527/5518/5515/5516 9 Cottontail_rabbit_papillomavirus R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 9/1598 14/10654 3.6766856921714455e-5 1.1387270615327203e-4 5.456792184689474e-5 1452/5519/2932/324/8312/5527/5518/5515/5516 9 Cottontail_rabbit_papillomavirus R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 9/1598 14/10654 3.6766856921714455e-5 1.1387270615327203e-4 5.456792184689474e-5 1452/5519/2932/324/8312/5527/5518/5515/5516 9 Cottontail_rabbit_papillomavirus R-HSA-5654743 Signaling by FGFR4 17/1598 41/10654 3.758886877790606e-5 1.1614338414355371e-4 5.5656033153798944e-5 4893/5290/5594/7316/6714/867/2247/2264/6233/7311/5518/3845/3265/7314/5595/5515/5516 17 Cottontail_rabbit_papillomavirus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 11/1598 20/10654 3.7788276152773505e-5 1.164841437067806e-4 5.5819325498759275e-5 1147/7321/8517/7098/7316/7189/6233/7311/7334/3551/7314 11 Cottontail_rabbit_papillomavirus R-HSA-196299 Beta-catenin phosphorylation cascade 10/1598 17/10654 3.961104979903338e-5 1.2181562844079205e-4 5.837417865120708e-5 1499/1452/5519/2932/324/8312/5527/5518/5515/5516 10 Cottontail_rabbit_papillomavirus R-HSA-190236 Signaling by FGFR 28/1598 87/10654 4.123797131224085e-5 1.265211936739408e-4 6.062909051342552e-5 2963/5434/4893/5290/5430/5594/3178/7316/3185/2263/6714/2962/2261/867/4670/2247/2264/6233/3187/7311/5518/3845/3265/5725/7314/5595/5515/5516 28 Cottontail_rabbit_papillomavirus R-HSA-9612973 Autophagy 35/1598 119/10654 4.183421610860055e-5 1.2804993080548226e-4 6.136166297206293e-5 5563/1459/1915/8878/9821/51422/7249/1080/1460/10533/10013/53632/7316/1457/8678/6714/3043/5571/3320/128866/81631/10542/6233/3326/2475/7311/84557/5562/7251/7431/3312/5564/11315/5565/7314 35 Cottontail_rabbit_papillomavirus R-HSA-187687 Signalling to ERKs 15/1598 34/10654 4.497120597849311e-5 1.370101776547564e-4 6.565542278788713e-5 4893/5604/5594/6714/1432/4914/4803/5603/1398/3845/5600/3265/6300/7529/5595 15 Cottontail_rabbit_papillomavirus R-HSA-4791275 Signaling by WNT in cancer 15/1598 34/10654 4.497120597849311e-5 1.370101776547564e-4 6.565542278788713e-5 27123/1487/1499/1452/89780/6934/5519/2932/324/54894/8312/5527/5518/5515/5516 15 Cottontail_rabbit_papillomavirus R-HSA-1852241 Organelle biogenesis and maintenance 70/1598 296/10654 4.6243370791321466e-5 1.4055833866106316e-4 6.735570531416469e-5 115106/10694/5563/22995/5442/8841/79718/22981/7531/203068/3842/11127/51807/7532/10575/1454/23408/23410/51422/7277/200186/10013/53632/3313/7203/10576/9611/5469/23409/983/54205/5566/1432/5571/1387/6950/7846/6907/7283/3320/10540/6648/10498/1385/54930/10499/23054/5518/10383/1386/55835/5347/403/23322/84790/22948/5600/3054/9662/1453/5564/6300/23373/5565/7019/8648/8481/814/7280/10891 70 Cottontail_rabbit_papillomavirus R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 12/1598 24/10654 5.7870280188113115e-5 1.7508438936542556e-4 8.390062551639207e-5 6118/1763/5982/5422/5111/6119/5985/5984/5983/6117/5981/10714 12 Cottontail_rabbit_papillomavirus R-HSA-452723 Transcriptional regulation of pluripotent stem cells 12/1598 24/10654 5.7870280188113115e-5 1.7508438936542556e-4 8.390062551639207e-5 7547/63978/6657/27086/5460/6774/57167/4089/9314/79923/2247/4087 12 Cottontail_rabbit_papillomavirus R-HSA-3214841 PKMTs methylate histone lysines 24/1598 71/10654 5.947323321257876e-5 1.795185122606015e-4 8.602546192168316e-5 55904/9070/11091/4790/9869/2146/6839/5929/5931/79813/5970/29072/2122/84444/5928/56950/23512/80854/58508/9739/8726/64754/4297/10919 24 Cottontail_rabbit_papillomavirus R-HSA-389513 CTLA4 inhibitory signaling 11/1598 21/10654 6.861783451144455e-5 2.0569612317994962e-4 9.856980090369267e-5 207/6714/5519/4067/10000/208/5527/3932/5518/5515/5516 11 Cottontail_rabbit_papillomavirus R-HSA-5621575 CD209 (DC-SIGN) signaling 11/1598 21/10654 6.861783451144455e-5 2.0569612317994962e-4 9.856980090369267e-5 4893/4790/5567/5568/5970/5566/1387/4067/2033/3845/3265 11 Cottontail_rabbit_papillomavirus R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 11/1598 21/10654 6.861783451144455e-5 2.0569612317994962e-4 9.856980090369267e-5 6118/328/5982/5111/6119/5985/5984/5983/6117/5981/10714 11 Cottontail_rabbit_papillomavirus R-HSA-204998 Cell death signalling via NRAGE, NRIF and NADE 25/1598 76/10654 7.011437778777424e-5 2.0970135416160395e-4 1.0048911184806857e-4 9181/4804/10018/7531/29/8878/1894/23385/9500/7316/9828/5664/836/4803/7189/83464/6233/7409/7311/26574/5599/55851/51107/5663/7314 25 Cottontail_rabbit_papillomavirus R-HSA-381033 ATF6 (ATF6-alpha) activates chaperones 8/1598 12/10654 7.078529618840373e-5 2.1026450481419014e-4 1.0075897423947421e-4 4802/7184/7494/1649/468/4800/3309/4801 8 Cottontail_rabbit_papillomavirus R-HSA-4641265 Repression of WNT target genes 8/1598 12/10654 7.078529618840373e-5 2.1026450481419014e-4 1.0075897423947421e-4 51176/7090/1487/7091/6934/3065/7088/7089 8 Cottontail_rabbit_papillomavirus R-HSA-8866907 Activation of the TFAP2 (AP-2) family of transcription factors 8/1598 12/10654 7.078529618840373e-5 2.1026450481419014e-4 1.0075897423947421e-4 7020/7021/51741/10370/1387/2033/7022/8089 8 Cottontail_rabbit_papillomavirus R-HSA-381119 Unfolded Protein Response (UPR) 29/1598 94/10654 7.228584420974114e-5 2.1423491696628494e-4 1.0266159996370922e-4 4000/4802/7184/7494/1051/1649/3576/468/84447/22872/4800/2081/55738/1054/30827/10954/8894/3309/4801/9451/6347/11340/467/81501/8570/23016/54512/9820/7709 29 Cottontail_rabbit_papillomavirus R-HSA-195258 RHO GTPase Effectors 75/1598 327/10654 7.409708897113288e-5 2.1910609793047663e-4 1.0499587506030976e-4 11130/25/5590/5903/5579/4638/1499/7531/5747/1058/4659/991/1856/4627/51807/2316/7532/10971/4771/5578/9212/5594/3985/6722/1027/79172/1080/7533/2810/7277/6232/7534/332/3688/5501/10398/6279/6714/3796/5519/1432/699/7846/999/995/998/23028/695/5527/1855/5580/701/1857/7514/6093/57120/367/8826/10499/5518/10383/5347/387/60/5300/84790/6396/5600/3071/7280/7529/4221/5595/5515/5516 75 Cottontail_rabbit_papillomavirus R-HSA-111471 Apoptotic factor-mediated response 10/1598 18/10654 7.71479589850262e-5 2.2658962335602077e-4 1.0858198839997773e-4 1029/842/5594/54205/836/331/581/317/578/5595 10 Cottontail_rabbit_papillomavirus R-HSA-1368082 RORA activates gene expression 10/1598 18/10654 7.71479589850262e-5 2.2658962335602077e-4 1.0858198839997773e-4 79718/6720/5469/1387/6907/2033/10498/10499/23054/8648 10 Cottontail_rabbit_papillomavirus R-HSA-5675482 Regulation of necroptotic cell death 10/1598 18/10654 7.71479589850262e-5 2.2658962335602077e-4 1.0858198839997773e-4 355/841/7316/8797/8837/6233/7311/331/8795/7314 10 Cottontail_rabbit_papillomavirus R-HSA-75893 TNF signaling 17/1598 43/10654 7.750171084549759e-5 2.2711824232077432e-4 1.0883530316986328e-4 7124/1147/841/27005/8517/7316/7128/9099/10616/10454/6868/6233/7311/331/1540/3551/7314 17 Cottontail_rabbit_papillomavirus R-HSA-4570464 SUMOylation of RNA binding proteins 18/1598 47/10654 7.866309770580248e-5 2.3000597024940456e-4 1.1021910546321082e-4 1912/5903/9631/8535/6045/80012/6613/3190/1911/4927/7341/84733/57332/7329/6396/648/8480/6015 18 Cottontail_rabbit_papillomavirus R-HSA-5099900 WNT5A-dependent internalization of FZD4 9/1598 15/10654 7.966473124129968e-5 2.3138178607195263e-4 1.1087839786800775e-4 5579/1856/1212/5578/5582/409/7474/1213/1211 9 Cottontail_rabbit_papillomavirus R-HSA-8866910 TFAP2 (AP-2) family regulates transcription of growth factors and their receptors 9/1598 15/10654 7.966473124129968e-5 2.3138178607195263e-4 1.1087839786800775e-4 7020/7021/3815/7422/2064/2099/7022/1956/7528 9 Cottontail_rabbit_papillomavirus R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 9/1598 15/10654 7.966473124129968e-5 2.3138178607195263e-4 1.1087839786800775e-4 2060/7316/4233/867/9146/6233/7311/10254/7314 9 Cottontail_rabbit_papillomavirus R-HSA-5673000 RAF activation 14/1598 32/10654 9.02305640312165e-5 2.6148857469800434e-4 1.2530560298418443e-4 4893/5604/6714/5519/3717/5527/5518/3845/3265/369/5245/7529/5515/5516 14 Cottontail_rabbit_papillomavirus R-HSA-1643713 Signaling by EGFR in Cancer 12/1598 25/10654 9.615829581779318e-5 2.774368490813591e-4 1.3294803302332274e-4 4893/5290/7316/1950/867/3320/6233/7311/1956/3845/3265/7314 12 Cottontail_rabbit_papillomavirus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 12/1598 25/10654 9.615829581779318e-5 2.774368490813591e-4 1.3294803302332274e-4 7321/991/8697/7316/51433/64682/6233/51434/701/7311/7314/996 12 Cottontail_rabbit_papillomavirus R-HSA-8854518 AURKA Activation by TPX2 24/1598 73/10654 9.822882656799101e-5 2.8278651172767454e-4 1.3551159705067157e-4 115106/22995/22981/7531/203068/7532/1454/22974/7277/983/6790/5566/7846/7283/3320/10540/54930/5518/10383/55835/5347/9662/1453/8481 24 Cottontail_rabbit_papillomavirus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 15/1598 36/10654 1.0031909484424497e-4 2.8816935595918277e-4 1.380910617289202e-4 4893/5604/5594/409/5908/6714/408/1445/8826/60/3845/3265/369/7529/5595 15 Cottontail_rabbit_papillomavirus R-HSA-165159 mTOR signalling 16/1598 40/10654 1.0634127644219466e-4 3.041313967394933e-4 1.4574008864011478e-4 5563/6194/207/51422/7249/53632/6198/5571/6794/208/10542/2475/5562/5564/5565/7529 16 Cottontail_rabbit_papillomavirus R-HSA-6783310 Fanconi Anemia Pathway 16/1598 40/10654 1.0634127644219466e-4 3.041313967394933e-4 1.4574008864011478e-4 6118/2176/545/7316/6119/84126/7398/57599/6233/2067/7311/2189/6117/2175/2188/7314 16 Cottontail_rabbit_papillomavirus R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 18/1598 48/10654 1.0839591226337489e-4 3.093306928563995e-4 1.4823159686671583e-4 2963/5434/902/5430/6749/4331/2962/8812/2965/2068/2071/2968/1025/11198/51497/1022/8178/25920 18 Cottontail_rabbit_papillomavirus R-HSA-199418 Negative regulation of the PI3K/AKT network 32/1598 110/10654 1.1059358432186196e-4 3.1491462899493157e-4 1.5090742500059137e-4 3643/5290/3815/207/5594/2064/2100/1950/2263/4233/6714/2099/5519/2261/5159/2247/10000/5728/2264/3630/2066/7189/208/5527/7409/3932/5518/1956/5156/5595/5515/5516 32 Cottontail_rabbit_papillomavirus R-HSA-391251 Protein folding 30/1598 101/10654 1.1856159218658337e-4 3.3390604839651225e-4 1.6000813336763565e-4 10694/9134/8841/1459/51807/8237/10575/898/1460/7277/7203/10576/908/6774/1457/26272/6950/7846/55294/2783/10238/7157/10574/10383/60/84790/22948/10693/2791/7280 30 Cottontail_rabbit_papillomavirus R-HSA-113510 E2F mediated regulation of DNA replication 11/1598 22/10654 1.1868980499068392e-4 3.3390604839651225e-4 1.6000813336763565e-4 7027/5925/5422/1869/891/983/84515/5519/5518/5515/5516 11 Cottontail_rabbit_papillomavirus R-HSA-186763 Downstream signal transduction 13/1598 29/10654 1.1879595447924882e-4 3.3390604839651225e-4 1.6000813336763565e-4 4893/5290/6778/6776/6774/6772/6714/5159/1398/3845/6777/3265/5156 13 Cottontail_rabbit_papillomavirus R-HSA-5654732 Negative regulation of FGFR3 signaling 13/1598 29/10654 1.1879595447924882e-4 3.3390604839651225e-4 1.6000813336763565e-4 5594/7316/6714/2261/867/2247/6233/7311/5518/7314/5595/5515/5516 13 Cottontail_rabbit_papillomavirus R-HSA-8863795 Downregulation of ERBB2 signaling 13/1598 29/10654 1.1879595447924882e-4 3.3390604839651225e-4 1.6000813336763565e-4 10273/207/2064/7316/1950/10000/3320/2066/208/6233/7311/1956/7314 13 Cottontail_rabbit_papillomavirus R-HSA-9619483 Activation of AMPK downstream of NMDARs 13/1598 29/10654 1.1879595447924882e-4 3.3390604839651225e-4 1.6000813336763565e-4 5563/51807/51422/7277/53632/5571/7846/5562/10383/84790/5564/5565/7280 13 Cottontail_rabbit_papillomavirus R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 10/1598 19/10654 0.00014101293723152181 3.955019505613713e-4 1.895249551677332e-4 7027/7153/5934/1869/5933/5111/4609/5928/1874/3065 10 Cottontail_rabbit_papillomavirus R-HSA-6806834 Signaling by MET 25/1598 79/10654 1.4197710143183686e-4 3.973534723156547e-4 1.9041220636074142e-4 4893/5290/85440/5747/10048/2060/5908/3688/7316/6774/4233/6714/3910/867/9146/6233/1398/5867/7311/57610/23163/3845/3265/10254/7314 25 Cottontail_rabbit_papillomavirus R-HSA-4615885 SUMOylation of DNA replication proteins 17/1598 45/10654 1.5069302119664993e-4 0.00042084568099149886 2.016696977328086e-4 7150/5903/9631/9212/51588/7153/6613/332/6790/5111/4927/7341/7329/6612/7155/6396/8480 17 Cottontail_rabbit_papillomavirus R-HSA-110373 Resolution of AP sites via the multiple-nucleotide patch replacement pathway 12/1598 26/10654 1.5432774552734738e-4 4.300775339109659e-4 2.060936114662141e-4 6118/328/5982/5111/6119/5985/142/5984/5983/6117/5981/10714 12 Cottontail_rabbit_papillomavirus R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 9/1598 16/10654 1.5785933114842958e-4 4.37123190277537e-4 2.0946989748732295e-4 7027/5934/1869/890/983/5933/5928/1874/3065 9 Cottontail_rabbit_papillomavirus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 9/1598 16/10654 1.5785933114842958e-4 4.37123190277537e-4 2.0946989748732295e-4 57154/5590/7316/7046/6233/7311/387/7040/7314 9 Cottontail_rabbit_papillomavirus R-HSA-2559584 Formation of Senescence-Associated Heterochromatin Foci (SAHF) 9/1598 16/10654 1.5785933114842958e-4 4.37123190277537e-4 2.0946989748732295e-4 3159/7290/5925/29855/25842/7157/8091/57634/23523 9 Cottontail_rabbit_papillomavirus R-HSA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 8/1598 13/10654 1.5979472289486503e-4 4.387640815621609e-4 2.1025621433534873e-4 7027/5925/5422/1869/5519/5518/5515/5516 8 Cottontail_rabbit_papillomavirus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 8/1598 13/10654 1.5979472289486503e-4 4.387640815621609e-4 2.1025621433534873e-4 207/2064/7316/10000/208/6233/7311/7314 8 Cottontail_rabbit_papillomavirus R-HSA-171007 p38MAPK events 8/1598 13/10654 1.5979472289486503e-4 4.387640815621609e-4 2.1025621433534873e-4 4893/6714/1432/5603/3845/5600/3265/6300 8 Cottontail_rabbit_papillomavirus R-HSA-202670 ERKs are inactivated 8/1598 13/10654 1.5979472289486503e-4 4.387640815621609e-4 2.1025621433534873e-4 5594/5519/5598/5518/51231/5595/5515/5516 8 Cottontail_rabbit_papillomavirus R-HSA-180786 Extension of Telomeres 13/1598 30/10654 1.810458026275804e-4 4.960730902185484e-4 2.3771875220878375e-4 6118/7015/1763/5982/5422/5111/6119/5985/5984/5983/6117/5981/10714 13 Cottontail_rabbit_papillomavirus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 14/1598 34/10654 1.9842439323116285e-4 5.425537279354181e-4 2.599923232163442e-4 7321/7706/7316/3093/7128/54941/83737/51191/6233/7311/55593/5300/1540/7314 14 Cottontail_rabbit_papillomavirus R-HSA-167169 HIV Transcription Elongation 17/1598 46/10654 2.059899837376039e-4 5.597274610084164e-4 2.682219943623467e-4 2963/5434/902/5430/6749/4331/2962/2965/2068/2071/2968/1025/11198/51497/1022/8178/25920 17 Cottontail_rabbit_papillomavirus R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 17/1598 46/10654 2.059899837376039e-4 5.597274610084164e-4 2.682219943623467e-4 2963/5434/902/5430/6749/4331/2962/2965/2068/2071/2968/1025/11198/51497/1022/8178/25920 17 Cottontail_rabbit_papillomavirus R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 17/1598 46/10654 2.059899837376039e-4 5.597274610084164e-4 2.682219943623467e-4 2963/5434/902/5430/6749/4331/2962/2965/2068/2071/2968/1025/11198/51497/1022/8178/25920 17 Cottontail_rabbit_papillomavirus R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 15/1598 38/10654 2.0738436123112945e-4 5.623472201848261e-4 2.694773857447522e-4 6627/27250/5908/3313/6175/3185/6950/3181/998/6648/2939/302/4282/5721/3586 15 Cottontail_rabbit_papillomavirus R-HSA-167044 Signalling to RAS 10/1598 20/10654 2.442375983102699e-4 6.568282736451085e-4 3.147528070058709e-4 4893/6714/1432/4914/4803/5603/3845/5600/3265/6300 10 Cottontail_rabbit_papillomavirus R-HSA-5213460 RIPK1-mediated regulated necrosis 10/1598 20/10654 2.442375983102699e-4 6.568282736451085e-4 3.147528070058709e-4 355/841/7316/8797/8837/6233/7311/331/8795/7314 10 Cottontail_rabbit_papillomavirus R-HSA-5218859 Regulated Necrosis 10/1598 20/10654 2.442375983102699e-4 6.568282736451085e-4 3.147528070058709e-4 355/841/7316/8797/8837/6233/7311/331/8795/7314 10 Cottontail_rabbit_papillomavirus R-HSA-622312 Inflammasomes 10/1598 20/10654 2.442375983102699e-4 6.568282736451085e-4 3.147528070058709e-4 834/596/351/4790/58484/7295/5970/598/10628/3326 10 Cottontail_rabbit_papillomavirus R-HSA-5654733 Negative regulation of FGFR4 signaling 13/1598 31/10654 2.6931707167451526e-4 7.227872950279085e-4 3.463604401736444e-4 5594/7316/6714/867/2247/2264/6233/7311/5518/7314/5595/5515/5516 13 Cottontail_rabbit_papillomavirus R-HSA-437239 Recycling pathway of L1 17/1598 47/10654 2.7814188582229104e-4 7.388850503449887e-4 3.540745016351373e-4 51807/5594/7277/8650/6714/7846/6195/6196/1759/1213/10383/1211/60/84790/6197/8986/7280 17 Cottontail_rabbit_papillomavirus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 17/1598 47/10654 2.7814188582229104e-4 7.388850503449887e-4 3.540745016351373e-4 4893/5604/5594/409/5908/6714/3717/408/1445/8826/60/3845/3265/369/5245/7529/5595 17 Cottontail_rabbit_papillomavirus R-HSA-6802949 Signaling by RAS mutants 17/1598 47/10654 2.7814188582229104e-4 7.388850503449887e-4 3.540745016351373e-4 4893/5604/5594/409/5908/6714/3717/408/1445/8826/60/3845/3265/369/5245/7529/5595 17 Cottontail_rabbit_papillomavirus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 17/1598 47/10654 2.7814188582229104e-4 7.388850503449887e-4 3.540745016351373e-4 4893/5604/5594/409/5908/6714/3717/408/1445/8826/60/3845/3265/369/5245/7529/5595 17 Cottontail_rabbit_papillomavirus R-HSA-9649948 Signaling downstream of RAS mutants 17/1598 47/10654 2.7814188582229104e-4 7.388850503449887e-4 3.540745016351373e-4 4893/5604/5594/409/5908/6714/3717/408/1445/8826/60/3845/3265/369/5245/7529/5595 17 Cottontail_rabbit_papillomavirus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 11/1598 24/10654 3.1433001940896845e-4 8.333252238692126e-4 3.993303331874372e-4 5606/8517/7316/1432/10454/7189/6233/7311/5600/7334/7314 11 Cottontail_rabbit_papillomavirus R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 7/1598 11/10654 3.188573470500639e-4 8.41912227463502e-4 4.0344523443867734e-4 7422/3091/10370/1387/2033/405/768 7 Cottontail_rabbit_papillomavirus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 7/1598 11/10654 3.188573470500639e-4 8.41912227463502e-4 4.0344523443867734e-4 7098/7316/10454/7189/6233/7311/7314 7 Cottontail_rabbit_papillomavirus R-HSA-174411 Polymerase switching on the C-strand of the telomere 8/1598 14/10654 3.2383187752573254e-4 8.498961123014708e-4 4.07271120540712e-4 5982/5422/5111/5985/5984/5983/5981/10714 8 Cottontail_rabbit_papillomavirus R-HSA-69091 Polymerase switching 8/1598 14/10654 3.2383187752573254e-4 8.498961123014708e-4 4.07271120540712e-4 5982/5422/5111/5985/5984/5983/5981/10714 8 Cottontail_rabbit_papillomavirus R-HSA-69109 Leading Strand Synthesis 8/1598 14/10654 3.2383187752573254e-4 8.498961123014708e-4 4.07271120540712e-4 5982/5422/5111/5985/5984/5983/5981/10714 8 Cottontail_rabbit_papillomavirus R-HSA-6807505 RNA polymerase II transcribes snRNA genes 23/1598 74/10654 3.470751788641206e-4 9.090726628765643e-4 4.3562858648697766e-4 6884/2963/5434/55197/5430/5451/6878/6667/2962/29101/8812/64859/1025/6880/6908/51593/80237/79035/6882/2961/1022/8178/6877 23 Cottontail_rabbit_papillomavirus R-HSA-112382 Formation of RNA Pol II elongation complex 20/1598 61/10654 3.8071852099507965e-4 9.932117903005372e-4 4.7594814579697954e-4 2963/5434/902/6830/5430/6749/4331/2962/8812/2965/2068/2071/2968/1025/11198/51497/1022/8178/55840/25920 20 Cottontail_rabbit_papillomavirus R-HSA-75955 RNA Polymerase II Transcription Elongation 20/1598 61/10654 3.8071852099507965e-4 9.932117903005372e-4 4.7594814579697954e-4 2963/5434/902/6830/5430/6749/4331/2962/8812/2965/2068/2071/2968/1025/11198/51497/1022/8178/55840/25920 20 Cottontail_rabbit_papillomavirus R-HSA-380259 Loss of Nlp from mitotic centrosomes 22/1598 70/10654 3.8939095965753246e-4 0.0010117971854321968 4.848542869022325e-4 115106/22995/22981/7531/203068/7532/1454/7277/983/5566/7846/7283/3320/10540/54930/5518/10383/55835/5347/9662/1453/8481 22 Cottontail_rabbit_papillomavirus R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 22/1598 70/10654 3.8939095965753246e-4 0.0010117971854321968 4.848542869022325e-4 115106/22995/22981/7531/203068/7532/1454/7277/983/5566/7846/7283/3320/10540/54930/5518/10383/55835/5347/9662/1453/8481 22 Cottontail_rabbit_papillomavirus R-HSA-73863 RNA Polymerase I Transcription Termination 13/1598 32/10654 3.9184994532519166e-4 0.0010161664256746537 4.869480314713639e-4 5434/902/9015/9014/51082/4331/9013/2965/2068/2071/2968/6908/1022 13 Cottontail_rabbit_papillomavirus R-HSA-3214847 HATs acetylate histones 37/1598 142/10654 0.00039853704649526063 0.0010314612272659517 4.942773166538407e-4 23774/8295/8464/55167/11091/64769/84148/7862/2648/10474/51147/6871/5931/117143/86/84289/11143/27097/8850/10524/1387/27154/2033/7994/6881/10499/57634/1386/6880/60/3054/10902/6883/51230/9913/8648/8089 37 Cottontail_rabbit_papillomavirus R-HSA-5674135 MAP2K and MAPK activation 15/1598 40/10654 4.013711912667071e-4 0.0010367433734893008 4.968085267395273e-4 4893/5604/5594/409/5908/6714/408/1445/8826/60/3845/3265/369/7529/5595 15 Cottontail_rabbit_papillomavirus R-HSA-210745 Regulation of gene expression in beta cells 10/1598 21/10654 4.0389192903647543e-4 0.0010391471481312469 4.979604181034043e-4 2308/3172/3171/207/6927/10000/3630/6514/208/5080 10 Cottontail_rabbit_papillomavirus R-HSA-5218921 VEGFR2 mediated cell proliferation 10/1598 21/10654 4.0389192903647543e-4 0.0010391471481312469 4.979604181034043e-4 5590/4893/5579/7422/5578/6714/5580/3791/3845/3265 10 Cottontail_rabbit_papillomavirus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 29/1598 103/10654 4.1852651705275327e-4 0.001074684003512669 5.149897169814666e-4 3643/5290/3815/207/5594/2064/2100/1950/2263/4233/6714/2099/5519/2261/5159/2247/2264/3630/2066/7189/5527/7409/3932/5518/1956/5156/5595/5515/5516 29 Cottontail_rabbit_papillomavirus R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 27/1598 94/10654 4.620215741662269e-4 0.00118404352438286 5.673949156427348e-4 10844/115106/22995/22981/7531/203068/51807/7532/1454/7277/983/5566/7846/7283/3320/80097/10540/54930/5518/10383/55835/5347/84790/9662/1453/8481/7280 27 Cottontail_rabbit_papillomavirus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 24/1598 80/10654 4.68054424249503e-4 0.0011971568150569482 5.73678818474517e-4 3837/3838/5903/9631/2316/25820/7706/9470/7316/6772/4927/6041/3840/6059/51191/6233/7311/5610/5300/6396/7334/8480/7314/5595 24 Cottontail_rabbit_papillomavirus R-HSA-4086398 Ca2+ pathway 20/1598 62/10654 4.839566692083603e-4 0.0012354128254986854 5.920111393482204e-4 27161/51176/1499/51701/4772/5578/57690/27327/192670/5530/6934/5534/2783/192669/23112/7474/4343/3845/26523/2791 20 Cottontail_rabbit_papillomavirus R-HSA-6802957 Oncogenic MAPK signaling 22/1598 71/10654 4.855718696453612e-4 0.0012371197536578697 5.928291011367393e-4 4000/8805/4893/5604/10018/5594/409/5908/10533/6714/3717/408/1445/8826/60/3845/3265/369/4763/5245/7529/5595 22 Cottontail_rabbit_papillomavirus R-HSA-113418 Formation of the Early Elongation Complex 13/1598 33/10654 5.586478484215868e-4 0.0014150246858275464 6.78081333763452e-4 2963/5434/902/5430/4331/2962/2965/2068/2071/2968/51497/1022/25920 13 Cottontail_rabbit_papillomavirus R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 13/1598 33/10654 5.586478484215868e-4 0.0014150246858275464 6.78081333763452e-4 2963/5434/902/5430/4331/2962/2965/2068/2071/2968/51497/1022/25920 13 Cottontail_rabbit_papillomavirus R-HSA-2871809 FCERI mediated Ca+2 mobilization 13/1598 33/10654 5.586478484215868e-4 0.0014150246858275464 6.78081333763452e-4 4773/2205/4772/5336/4775/2206/5530/6850/4067/5534/695/7409/2207 13 Cottontail_rabbit_papillomavirus R-HSA-2032785 YAP1- and WWTR1 (TAZ)-stimulated gene expression 8/1598 15/10654 6.028800447079384e-4 0.0015182354883107427 7.275400600369605e-4 8463/204851/28996/8850/25937/860/2626/1482 8 Cottontail_rabbit_papillomavirus R-HSA-5637810 Constitutive Signaling by EGFRvIII 8/1598 15/10654 6.028800447079384e-4 0.0015182354883107427 7.275400600369605e-4 4893/5290/1950/867/3320/1956/3845/3265 8 Cottontail_rabbit_papillomavirus R-HSA-5637812 Signaling by EGFRvIII in Cancer 8/1598 15/10654 6.028800447079384e-4 0.0015182354883107427 7.275400600369605e-4 4893/5290/1950/867/3320/1956/3845/3265 8 Cottontail_rabbit_papillomavirus R-HSA-73854 RNA Polymerase I Promoter Clearance 30/1598 110/10654 6.051544883318628e-4 0.0015210325312495089 7.288804059867579e-4 5434/902/9015/2648/2074/9112/9219/9014/5931/51082/4331/9013/1108/8850/5928/57459/2965/54815/2068/3066/3065/2071/1107/2968/57504/6908/53615/1022/10919/5595 30 Cottontail_rabbit_papillomavirus R-HSA-912631 Regulation of signaling by CBL 10/1598 22/10654 6.415603657413039e-4 0.0016094422226945954 7.712464241157205e-4 5290/7316/6850/867/4067/6233/1398/7409/7311/7314 10 Cottontail_rabbit_papillomavirus R-HSA-5689877 Josephin domain DUBs 7/1598 12/10654 6.661582182563861e-4 0.001664758683099611 7.97754130748817e-4 4287/7316/7415/6233/7311/5886/7314 7 Cottontail_rabbit_papillomavirus R-HSA-9634600 Regulation of glycolysis by fructose 2,6-bisphosphate metabolism 7/1598 12/10654 6.661582182563861e-4 0.001664758683099611 7.97754130748817e-4 5567/5568/5566/5519/5518/5515/5516 7 Cottontail_rabbit_papillomavirus R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 24/1598 82/10654 6.959232912224476e-4 0.0017325176031004553 8.302242772478323e-4 10844/115106/22995/22981/7531/203068/7532/1454/7277/983/5566/7846/7283/3320/80097/10540/54930/5518/10383/55835/5347/9662/1453/8481 24 Cottontail_rabbit_papillomavirus R-HSA-380287 Centrosome maturation 24/1598 82/10654 6.959232912224476e-4 0.0017325176031004553 8.302242772478323e-4 10844/115106/22995/22981/7531/203068/7532/1454/7277/983/5566/7846/7283/3320/80097/10540/54930/5518/10383/55835/5347/9662/1453/8481 24 Cottontail_rabbit_papillomavirus R-HSA-5250913 Positive epigenetic regulation of rRNA expression 29/1598 106/10654 7.006445164390217e-4 0.0017376515806182189 8.326844847322839e-4 8467/23451/5434/9015/10514/2648/2074/9112/9219/9014/5931/51082/9013/4641/1108/8850/5928/2932/57459/54815/2033/3066/3065/1107/57504/6908/60/53615/10919 29 Cottontail_rabbit_papillomavirus R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 29/1598 106/10654 7.006445164390217e-4 0.0017376515806182189 8.326844847322839e-4 9318/1856/4738/2060/1212/409/1080/29978/7316/1950/7037/3949/867/9146/408/10987/6233/7474/2873/7311/1213/1956/1211/29924/4036/6869/10254/7314/51138 29 Cottontail_rabbit_papillomavirus R-HSA-180024 DARPP-32 events 11/1598 26/10654 7.287941295272827e-4 0.0018040415289624215 8.644986185580806e-4 5567/5568/5530/5566/5519/5534/5499/5518/1020/5515/5516 11 Cottontail_rabbit_papillomavirus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 14/1598 38/10654 7.66001846547614e-4 0.0018925603278596057 9.069169210940809e-4 5903/9631/51588/4927/7341/7428/7329/5987/5371/9063/6396/8480/4193/8554 14 Cottontail_rabbit_papillomavirus R-HSA-5654727 Negative regulation of FGFR2 signaling 13/1598 34/10654 7.816433206823241e-4 0.0019275619247769763 9.236897235471357e-4 5594/7316/2263/6714/867/2247/6233/7311/5518/7314/5595/5515/5516 13 Cottontail_rabbit_papillomavirus R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 9/1598 19/10654 8.318840955527861e-4 0.0020437453249764876 9.793649324374906e-4 7321/991/8697/51433/8556/64682/51434/51343/996 9 Cottontail_rabbit_papillomavirus R-HSA-176412 Phosphorylation of the APC/C 9/1598 19/10654 8.318840955527861e-4 0.0020437453249764876 9.793649324374906e-4 7321/8697/891/983/51433/64682/51434/5347/996 9 Cottontail_rabbit_papillomavirus R-HSA-73864 RNA Polymerase I Transcription 30/1598 112/10654 8.364934545961607e-4 0.0020512137807827055 9.829438243995569e-4 5434/902/9015/2648/2074/9112/9219/9014/5931/51082/4331/9013/1108/8850/5928/57459/2965/54815/2068/3066/3065/2071/1107/2968/57504/6908/53615/1022/10919/5595 30 Cottontail_rabbit_papillomavirus R-HSA-9020591 Interleukin-12 signaling 16/1598 47/10654 9.022686385275314e-4 0.0022083616302537145 0.0010582492409301819 6627/27250/5908/3313/6175/3185/6950/3717/3181/998/6648/2939/302/4282/5721/3586 16 Cottontail_rabbit_papillomavirus R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 11/1598 27/10654 0.001064765480882063 0.0025915241778637923 0.0012418611410856169 2963/5434/902/5430/4331/2962/2965/2068/2071/2968/1022 11 Cottontail_rabbit_papillomavirus R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 11/1598 27/10654 0.001064765480882063 0.0025915241778637923 0.0012418611410856169 1612/842/355/841/9500/8797/836/8837/1613/26060/8795 11 Cottontail_rabbit_papillomavirus R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 11/1598 27/10654 0.001064765480882063 0.0025915241778637923 0.0012418611410856169 2963/5434/902/5430/4331/2962/2965/2068/2071/2968/1022 11 Cottontail_rabbit_papillomavirus R-HSA-182971 EGFR downregulation 12/1598 31/10654 0.0010900400961329985 0.0026481085606799796 0.0012689764374860773 2060/7316/1950/867/9146/998/6233/7311/1956/29924/10254/7314 12 Cottontail_rabbit_papillomavirus R-HSA-373760 L1CAM interactions 31/1598 119/10654 0.001141206370275291 0.002767266652968099 0.001326077121987693 5604/1459/51807/10048/5594/1460/7277/3688/8650/1272/1457/6714/7846/6195/2048/287/6196/1759/1213/10383/1956/1211/60/84790/27255/6197/8986/3312/100133941/7280/5595 31 Cottontail_rabbit_papillomavirus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 16/1598 48/10654 0.001167788764065607 0.00282648132339583 0.0013544528550078676 5290/7534/6776/7316/6850/5566/867/3558/4067/3717/6233/1398/7409/7311/6777/7314 16 Cottontail_rabbit_papillomavirus R-HSA-447115 Interleukin-12 family signaling 18/1598 57/10654 0.0012054508510199553 0.002912244477417896 0.0013955506495901809 6627/27250/5908/3313/6175/3185/6774/6772/6950/3717/3181/998/6648/2939/302/4282/5721/3586 18 Cottontail_rabbit_papillomavirus R-HSA-111461 Cytochrome c-mediated apoptotic response 7/1598 13/10654 0.001256915629511492 0.0030244634704428767 0.0014493261103479338 842/5594/54205/836/331/317/5595 7 Cottontail_rabbit_papillomavirus R-HSA-2892247 POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation 7/1598 13/10654 0.001256915629511492 0.0030244634704428767 0.0014493261103479338 7547/6657/5460/6774/57167/79923/2247 7 Cottontail_rabbit_papillomavirus R-HSA-5663220 RHO GTPases Activate Formins 35/1598 140/10654 0.0012588432501307767 0.0030244634704428767 0.0014493261103479338 11130/5903/1058/991/1856/51807/9212/6722/79172/7277/6232/332/3688/5501/6714/3796/5519/699/7846/998/5527/1855/701/1857/7514/5518/10383/5347/387/60/84790/6396/7280/5515/5516 35 Cottontail_rabbit_papillomavirus R-HSA-1632852 Macroautophagy 26/1598 95/10654 0.0012861056340253783 0.0030842936948094852 0.0014779968174700145 5563/1459/8878/9821/51422/7249/1460/10533/53632/7316/1457/8678/6714/5571/128866/81631/10542/6233/2475/7311/84557/5562/3312/5564/5565/7314 26 Cottontail_rabbit_papillomavirus R-HSA-174437 Removal of the Flap Intermediate from the C-strand 6/1598 10/10654 0.001374226000615875 0.003265660696008998 0.0015649080772563552 6118/1763/5111/6119/6117/10714 6 Cottontail_rabbit_papillomavirus R-HSA-2465910 MASTL Facilitates Mitotic Progression 6/1598 10/10654 0.001374226000615875 0.003265660696008998 0.0015649080772563552 891/983/5519/5518/5515/5516 6 Cottontail_rabbit_papillomavirus R-HSA-418889 Caspase activation via Dependence Receptors in the absence of ligand 6/1598 10/10654 0.001374226000615875 0.003265660696008998 0.0015649080772563552 1612/842/9500/836/1613/26060 6 Cottontail_rabbit_papillomavirus R-HSA-8866904 Negative regulation of activity of TFAP2 (AP-2) family transcription factors 6/1598 10/10654 0.001374226000615875 0.003265660696008998 0.0015649080772563552 7020/7021/51741/7341/7022/7329 6 Cottontail_rabbit_papillomavirus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 6/1598 10/10654 0.001374226000615875 0.003265660696008998 0.0015649080772563552 7316/10454/7189/6233/7311/7314 6 Cottontail_rabbit_papillomavirus R-HSA-6802952 Signaling by BRAF and RAF fusions 20/1598 67/10654 0.0014448887547639474 0.0034273495507740094 0.0016423895483514163 4000/8805/4893/5604/10018/5594/409/5908/10533/6714/3717/408/1445/8826/60/3845/3265/369/7529/5595 20 Cottontail_rabbit_papillomavirus R-HSA-203927 MicroRNA (miRNA) biogenesis 10/1598 24/10654 0.001461812011110845 0.003448715340292192 0.0016526280574025323 27161/5434/5430/192670/54487/57510/192669/29102/26523/23405 10 Cottontail_rabbit_papillomavirus R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 10/1598 24/10654 0.001461812011110845 0.003448715340292192 0.0016526280574025323 5590/5579/5578/5594/6279/1432/5580/5300/5600/5595 10 Cottontail_rabbit_papillomavirus R-HSA-982772 Growth hormone receptor signaling 10/1598 24/10654 0.001461812011110845 0.003448715340292192 0.0016526280574025323 5594/6776/6774/6772/8651/4067/3717/6868/6777/5595 10 Cottontail_rabbit_papillomavirus R-HSA-5626467 RHO GTPases activate IQGAPs 12/1598 32/10654 0.0015089541866176784 0.0035531999065756925 0.001702697172643287 1499/51807/7277/7846/999/998/8826/10383/60/84790/7280/4221 12 Cottontail_rabbit_papillomavirus R-HSA-2500257 Resolution of Sister Chromatid Cohesion 32/1598 126/10654 0.0015115372211599734 0.0035531999065756925 0.001702697172643287 11130/5903/55869/1058/991/51807/9212/79172/23244/7277/6232/332/891/5501/983/3796/5519/699/7846/8243/9126/5527/701/7514/5518/10383/5347/84790/6396/7280/5515/5516 32 Cottontail_rabbit_papillomavirus R-HSA-1169408 ISG15 antiviral mechanism 21/1598 72/10654 0.0015389644235210096 0.003611178638315906 0.001730480642530475 3837/3838/5903/9631/25820/7706/9470/7316/6772/4927/3840/51191/6233/7311/5610/5300/6396/7334/8480/7314/5595 21 Cottontail_rabbit_papillomavirus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 8/1598 17/10654 0.001720800412134961 0.004023409908158128 0.001928022305282557 1147/4790/8517/7098/5970/4792/4793/3551 8 Cottontail_rabbit_papillomavirus R-HSA-450604 KSRP (KHSRP) binds and destabilizes mRNA 8/1598 17/10654 0.001720800412134961 0.004023409908158128 0.001928022305282557 207/7534/1432/11340/5600/8570/23016/54512 8 Cottontail_rabbit_papillomavirus R-HSA-5654736 Signaling by FGFR1 16/1598 50/10654 0.001899322326308516 0.004432882643723626 0.00212424207547663 4893/5290/5594/7316/6714/867/2247/6233/7311/5518/3845/3265/7314/5595/5515/5516 16 Cottontail_rabbit_papillomavirus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 9/1598 21/10654 0.001994281159673622 0.004637945686287231 0.0022225085034759417 1147/4790/23220/8517/7098/5970/4792/4793/3551 9 Cottontail_rabbit_papillomavirus R-HSA-6807004 Negative regulation of MET activity 9/1598 21/10654 0.001994281159673622 0.004637945686287231 0.0022225085034759417 2060/7316/4233/867/9146/6233/7311/10254/7314 9 Cottontail_rabbit_papillomavirus R-HSA-5654726 Negative regulation of FGFR1 signaling 12/1598 33/10654 0.002051986379872593 0.004763669979562129 0.00228275571847096 5594/7316/6714/867/2247/6233/7311/5518/7314/5595/5515/5516 12 Cottontail_rabbit_papillomavirus R-HSA-9006335 Signaling by Erythropoietin 10/1598 25/10654 0.002112519578935775 0.004868095429134878 0.0023327965049210744 4893/5290/5336/6776/4067/3717/7409/3845/6777/3265 10 Cottontail_rabbit_papillomavirus R-HSA-937041 IKK complex recruitment mediated by RIP1 10/1598 25/10654 0.002112519578935775 0.004868095429134878 0.0023327965049210744 1147/7321/8517/7316/7189/6233/7311/7334/3551/7314 10 Cottontail_rabbit_papillomavirus R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF) 17/1598 55/10654 0.002117933831942107 0.004868095429134878 0.0023327965049210744 3837/79718/4802/6721/3638/6720/5469/4800/6667/1387/6907/4801/10498/9871/10499/23054/8648 17 Cottontail_rabbit_papillomavirus R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK 11/1598 29/10654 0.002119316219722835 0.004868095429134878 0.0023327965049210744 5563/51422/7249/53632/5571/6794/10542/2475/5562/5564/5565 11 Cottontail_rabbit_papillomavirus R-HSA-5205647 Mitophagy 11/1598 29/10654 0.002119316219722835 0.004868095429134878 0.0023327965049210744 1459/8878/1460/7316/1457/6714/81631/6233/7311/84557/7314 11 Cottontail_rabbit_papillomavirus R-HSA-72086 mRNA Capping 11/1598 29/10654 0.002119316219722835 0.004868095429134878 0.0023327965049210744 2963/5434/902/5430/4331/2962/2965/2068/2071/2968/1022 11 Cottontail_rabbit_papillomavirus R-HSA-5693571 Nonhomologous End-Joining (NHEJ) 20/1598 69/10654 0.0021402611016170686 0.004907581157567558 0.0023517181079633536 10111/51588/7520/51720/472/7336/580/5591/64421/9656/7341/10524/4683/8924/672/7158/79184/7334/2547/55183 20 Cottontail_rabbit_papillomavirus R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 7/1598 14/10654 0.0021899993814972585 0.004995338903345405 0.00239377171303549 2801/5594/891/983/8615/5347/5595 7 Cottontail_rabbit_papillomavirus R-HSA-169893 Prolonged ERK activation events 7/1598 14/10654 0.0021899993814972585 0.004995338903345405 0.00239377171303549 5604/5594/4914/4803/1398/7529/5595 7 Cottontail_rabbit_papillomavirus R-HSA-69166 Removal of the Flap Intermediate 7/1598 14/10654 0.0021899993814972585 0.004995338903345405 0.00239377171303549 6118/1763/5422/5111/6119/6117/10714 7 Cucumber_mosaic_virus R-HSA-5663205 Infectious disease 218/1181 383/10654 6.121033578131026e-112 7.767591610648272e-109 3.3569036781118575e-109 6158/6884/23165/3303/6138/8945/4928/6144/2963/3837/3838/2237/6917/6203/51606/5434/5440/5684/5903/6227/9349/8065/4736/902/6206/6194/6234/6191/55706/7175/6166/6128/5606/51121/6132/9631/1499/1938/6147/6159/6129/25978/6217/2959/5430/6222/5436/6176/6152/6136/8106/6878/6125/4869/6500/404672/6749/811/6224/6146/51065/6154/348995/6141/9636/10015/6202/79023/6123/57122/5705/5441/23636/6232/5438/6134/3981/6169/10762/5431/6160/7469/23511/6164/5435/4686/7316/6155/10213/6175/9978/5433/6218/2960/53371/920/292/4331/4836/6209/51271/6193/6714/6173/23279/6210/4927/5605/6231/6229/9688/11224/8148/6205/2966/6165/8731/79902/6130/6879/9150/2962/6142/6167/6204/9883/5701/2958/6228/5437/8812/23521/116832/23225/999/9146/3320/8815/2965/2534/140801/6156/27183/6235/905/6143/5710/2068/6181/5439/6124/2071/5901/6207/8086/5478/6827/6139/5609/30011/5704/6233/2885/3326/2968/1025/7311/6223/25873/9972/2967/3932/1213/6908/3921/6188/6189/8021/7040/808/11198/6135/6201/129401/904/6161/7936/6829/1104/51497/2547/801/9045/6882/2961/6187/1022/5432/55746/6168/22916/5693/6208/6157/6137/8178/6170/200916/8480/6122/6877/6133/2957/7314/5879/805/25920/6230 218 Cucumber_mosaic_virus R-HSA-168273 Influenza Viral RNA Transcription and Replication 124/1181 134/10654 1.1430806454493803e-107 6.807286484814749e-105 2.9418906379565214e-105 6158/23165/6138/4928/6144/2963/6203/5434/5440/5903/6227/9349/4736/6206/6194/6234/6191/55706/7175/6166/6128/51121/6132/9631/6147/6159/6129/6217/5430/6222/5436/6176/6152/6136/6125/6224/6146/51065/6154/348995/6141/6202/79023/6123/57122/5441/23636/6232/5438/6134/6169/10762/5431/6160/23511/6164/5435/6155/6175/5433/6218/53371/6209/6193/6173/23279/6210/4927/6231/6229/9688/11224/6205/6165/79902/6130/2962/6142/6167/6204/9883/6228/5437/23521/116832/23225/3320/140801/6156/6235/6143/6181/5439/6124/6207/8086/6139/6233/7311/6223/25873/9972/3921/6188/6189/8021/6135/6201/129401/6161/9045/6187/5432/55746/6168/6208/6157/6137/6170/200916/8480/6122/6133/6230 124 Cucumber_mosaic_virus R-HSA-168255 Influenza Life Cycle 129/1181 144/10654 1.6092875850625884e-107 6.807286484814749e-105 2.9418906379565214e-105 6158/23165/3303/6138/4928/6144/2963/3837/6203/5434/5440/5903/6227/9349/4736/6206/6194/6234/6191/55706/7175/6166/6128/51121/6132/9631/6147/6159/6129/6217/5430/6222/5436/6176/6152/6136/6125/811/6224/6146/51065/6154/348995/6141/6202/79023/6123/57122/5441/23636/6232/5438/6134/6169/10762/5431/6160/23511/6164/5435/6155/6175/5433/6218/53371/6209/6193/6173/23279/6210/4927/6231/6229/9688/11224/6205/6165/79902/6130/2962/6142/6167/6204/9883/6228/5437/23521/116832/23225/3320/140801/6156/6235/6143/6181/5439/6124/5901/6207/8086/6139/6233/7311/6223/25873/9972/1213/3921/6188/6189/8021/6135/6201/129401/6161/9045/6187/5432/55746/6168/6208/6157/6137/6170/200916/8480/6122/6133/6230 129 Cucumber_mosaic_virus R-HSA-168254 Influenza Infection 133/1181 155/10654 2.5995164413515843e-105 8.246965910187902e-103 3.56407385774783e-103 6158/23165/3303/6138/4928/6144/2963/3837/3838/6203/5434/5440/5903/6227/9349/4736/6206/6194/6234/6191/55706/7175/6166/6128/51121/6132/9631/6147/6159/6129/6217/5430/6222/5436/6176/6152/6136/8106/6125/811/6224/6146/51065/6154/348995/6141/9636/6202/79023/6123/57122/5441/23636/6232/5438/6134/6169/10762/5431/6160/23511/6164/5435/6155/6175/5433/6218/53371/6209/6193/6173/23279/6210/4927/6231/6229/9688/11224/6205/6165/79902/6130/2962/6142/6167/6204/9883/6228/5437/23521/116832/23225/3320/140801/6156/6235/6143/6181/5439/6124/5901/6207/8086/6139/6233/7311/6223/25873/9972/1213/3921/6188/6189/8021/7040/6135/6201/129401/6161/9045/6187/5432/55746/6168/6208/6157/6137/6170/200916/8480/6122/6133/6230 133 Cucumber_mosaic_virus R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 109/1181 112/10654 1.2663301237541138e-101 3.2139458540879413e-99 1.3889641988966177e-99 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6147/6159/8666/6129/6217/6222/1983/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 109 Cucumber_mosaic_virus R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 108/1181 111/10654 1.2109702463442734e-100 2.5612020710181383e-98 1.106869295342748e-98 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6147/6159/8666/6129/6217/6222/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 108 Cucumber_mosaic_virus R-HSA-72613 Eukaryotic Translation Initiation 111/1181 119/10654 2.6489346926201426e-97 4.2018726561687015e-95 1.8159144405988083e-95 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6147/6159/8666/6129/6217/6222/1983/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/1978/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 111 Cucumber_mosaic_virus R-HSA-72737 Cap-dependent Translation Initiation 111/1181 119/10654 2.6489346926201426e-97 4.2018726561687015e-95 1.8159144405988083e-95 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6147/6159/8666/6129/6217/6222/1983/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/1978/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 111 Cucumber_mosaic_virus R-HSA-72689 Formation of a pool of free 40S subunits 98/1181 101/10654 7.291544590862243e-91 1.0281077873115764e-88 4.443151733145297e-89 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/6234/27335/6191/6166/6128/51121/6132/6147/6159/8666/6129/6217/6222/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/8663/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 98 Cucumber_mosaic_virus R-HSA-156842 Eukaryotic Translation Elongation 90/1181 93/10654 4.4810719321105445e-83 5.686480281848281e-81 2.457514185925888e-81 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/1917/1938/6147/6159/6129/1915/6217/1936/6222/6176/6152/6136/6125/1937/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/1933/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 90 Cucumber_mosaic_virus R-HSA-156902 Peptide chain elongation 86/1181 89/10654 3.415867580292275e-79 3.9406690539917245e-77 1.7030306309399763e-77 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/1938/6147/6159/6129/1915/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 86 Cucumber_mosaic_virus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 89/1181 95/10654 2.100451911362336e-78 2.2212278962656703e-76 9.599433735261204e-77 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6147/6159/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/6232/6134/6169/6160/6164/4686/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/1981/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/5976/6187/6168/22916/6208/6157/6137/6170/200916/6122/6133/6230 89 Cucumber_mosaic_virus R-HSA-192823 Viral mRNA Translation 84/1181 89/10654 9.338094904253209e-75 9.115417256536401e-73 3.93939064381856e-73 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6147/6159/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 84 Cucumber_mosaic_virus R-HSA-2408557 Selenocysteine synthesis 84/1181 93/10654 1.4032869622545958e-70 1.1871807700673879e-68 5.130614086558909e-69 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6147/6159/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 84 Cucumber_mosaic_virus R-HSA-72764 Eukaryotic Translation Termination 84/1181 93/10654 1.4032869622545958e-70 1.1871807700673879e-68 5.130614086558909e-69 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6147/6159/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 84 Cucumber_mosaic_virus R-HSA-927802 Nonsense-Mediated Decay (NMD) 94/1181 115/10654 2.9739735018093965e-70 2.2199837492918374e-68 9.59405693153372e-69 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6147/6159/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/6232/26019/6134/6169/6160/6164/4686/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/1981/140801/6156/6235/6143/6181/6124/6207/9939/6139/6233/7311/6223/25873/5518/3921/6188/6189/9775/6135/6201/6161/9045/5976/6187/6168/22916/6208/6157/6137/6170/200916/6122/6133/5515/6230 94 Cucumber_mosaic_virus R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 94/1181 115/10654 2.9739735018093965e-70 2.2199837492918374e-68 9.59405693153372e-69 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6147/6159/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/6232/26019/6134/6169/6160/6164/4686/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/1981/140801/6156/6235/6143/6181/6124/6207/9939/6139/6233/7311/6223/25873/5518/3921/6188/6189/9775/6135/6201/6161/9045/5976/6187/6168/22916/6208/6157/6137/6170/200916/6122/6133/5515/6230 94 Cucumber_mosaic_virus R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 89/1181 112/10654 1.7845730519306333e-64 1.2581240016110965e-62 5.437207953543041e-63 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6147/6159/6129/6217/6222/1650/6176/6152/6136/6125/6727/6224/6146/51065/6154/6141/6184/6202/6123/6232/58477/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6185/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 89 Cucumber_mosaic_virus R-HSA-6807505 RNA polymerase II transcribes snRNA genes 70/1181 74/10654 1.568061654264938e-62 1.0473001259274769e-60 4.526094858016802e-61 6884/2963/5434/5440/57508/55197/26173/2959/5430/5436/5451/55174/51585/26512/6878/6617/79871/5441/84524/5438/5431/55756/5435/23379/4686/5433/2960/55656/6667/58490/2962/29101/79664/2958/51808/5437/8812/25896/23248/129685/92105/905/5452/64859/5439/22936/6827/80789/57117/1025/10302/6621/6908/7702/51593/80237/6619/79035/904/6829/6882/2961/65123/1022/5432/22916/6618/8178/6877/2957 70 Cucumber_mosaic_virus R-HSA-3700989 Transcriptional Regulation by TP53 162/1181 365/10654 1.6301088461615067e-61 1.034304062889476e-59 4.4699300465797106e-60 6884/1017/834/5170/27161/5563/2963/6917/5434/5440/4436/8621/902/7531/389541/6446/5430/8445/207/10971/5436/835/4849/6878/4869/51422/7249/404672/58528/7295/4850/1460/6749/4292/11200/545/472/53632/117584/5441/192670/7534/5438/153129/580/5431/7469/7001/9337/5435/7316/5433/891/890/2539/84289/1457/4331/983/1026/5111/25904/1108/8148/2966/246175/64223/6879/9150/2962/9656/5519/1432/5571/1387/4683/4848/10325/5437/8812/23019/843/2821/8649/2177/6794/2965/51755/2033/1874/10128/84126/5728/25824/6009/905/2068/5439/1111/192669/3066/3065/2071/7157/1107/55215/5984/6827/5371/208/10542/6233/79109/2968/2475/55004/672/55571/1025/7311/839/2967/5562/5518/1386/10670/6908/8851/5300/5983/11198/5600/57472/904/4697/7936/85456/6829/29883/26523/51497/5564/6882/5052/5565/1020/64121/1022/5432/665/57521/7248/8178/6877/7529/7314/253260/28956/4193/5515/25920/5516 162 Cucumber_mosaic_virus R-HSA-162587 HIV Life Cycle 96/1181 152/10654 2.58208021622029e-54 1.5603141878016896e-52 6.74317690551765e-53 6884/23165/4928/2963/2237/6917/5434/5440/5903/902/55706/7175/9631/25978/2959/5430/5436/6878/404672/6749/348995/10015/79023/57122/5441/23636/5438/3981/10762/5431/7469/23511/5435/4686/7316/5433/2960/53371/920/4331/4836/51271/23279/4927/9688/8148/2966/8731/79902/6879/9150/2962/9883/2958/5437/8812/23225/8815/2965/27183/905/2068/5439/2071/5901/8086/5478/6827/6233/2968/1025/7311/9972/2967/6908/8021/11198/129401/904/7936/6829/1104/51497/2547/6882/2961/1022/5432/55746/22916/8178/8480/6877/2957/7314/25920 96 Cucumber_mosaic_virus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 102/1181 171/10654 3.1017422323856813e-54 1.789141314953377e-52 7.732094273076268e-53 6158/6138/6144/6203/5684/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6147/6159/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/5705/6232/26019/6134/6169/6160/6164/4686/7316/6155/10213/6175/9978/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/5701/6228/23521/116832/1981/140801/6156/6235/6143/5710/6181/6124/8453/6207/9939/6139/5704/6233/7311/6223/25873/3921/6188/6189/9775/6135/6201/6161/9045/6187/6168/22916/5693/6208/6157/6137/6170/200916/6122/6133/7314/6230 102 Cucumber_mosaic_virus R-HSA-2408522 Selenoamino acid metabolism 84/1181 118/10654 4.647794402481445e-54 2.5643700420647625e-52 1.1082383907061019e-52 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6147/6159/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 84 Cucumber_mosaic_virus R-HSA-162599 Late Phase of HIV Life Cycle 91/1181 139/10654 1.5919416566036865e-53 8.417391509291992e-52 3.637726329344389e-52 6884/23165/4928/2963/6917/5434/5440/5903/902/55706/7175/9631/25978/2959/5430/5436/6878/404672/6749/348995/10015/79023/57122/5441/23636/5438/10762/5431/7469/23511/5435/4686/7316/5433/2960/53371/4331/4836/51271/23279/4927/9688/8148/2966/8731/79902/6879/9150/2962/9883/2958/5437/8812/23225/2965/27183/905/2068/5439/2071/5901/8086/5478/6827/6233/2968/1025/7311/9972/2967/6908/8021/11198/129401/904/7936/6829/1104/51497/6882/2961/1022/5432/55746/22916/8178/8480/6877/2957/7314/25920 91 Cucumber_mosaic_virus R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 57/1181 59/10654 1.4332825575019483e-52 7.275342261879888e-51 3.1441693156148003e-51 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/8668/8667/6224/51065/8662/10480/26986/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/8665/6201/1978/6187/6208/1974/1968/6230 57 Cucumber_mosaic_virus R-HSA-72649 Translation initiation complex formation 56/1181 58/10654 1.3042981222451259e-51 6.130201174552091e-50 2.6492761079520886e-50 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/8668/8667/6224/51065/8662/10480/26986/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1974/1968/6230 56 Cucumber_mosaic_virus R-HSA-72702 Ribosomal scanning and start codon recognition 56/1181 58/10654 1.3042981222451259e-51 6.130201174552091e-50 2.6492761079520886e-50 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/1983/8668/8667/6224/51065/8662/10480/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1974/1968/6230 56 Cucumber_mosaic_virus R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 102/1181 185/10654 9.926032414740013e-50 4.498619690823241e-48 1.9441589804810327e-48 6158/6138/6144/2091/6203/6227/9349/4736/6206/6194/6234/22803/6191/6166/6128/51121/6132/6147/6159/6129/6217/6222/6176/6152/6136/10528/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/55272/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/9790/51077/140801/6156/117246/10171/6235/5822/6143/6181/6124/6207/6139/6233/7311/6223/25873/83732/27341/3921/6188/6189/51010/6135/6201/6161/56915/1453/9045/6187/4691/6168/6208/54512/6157/6137/6170/22984/200916/6122/6133/9188/6230 102 Cucumber_mosaic_virus R-HSA-376176 Signaling by ROBO receptors 111/1181 218/10654 1.9427526689367605e-49 8.501217713381893e-48 3.6739533231072675e-48 6158/6138/6144/25/6203/5684/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6147/6159/6129/6217/5567/6222/6176/6152/6136/5578/5568/6125/6224/6146/51065/6154/6141/26986/6202/6123/5705/6232/26019/6134/6169/6160/6164/4686/7316/6155/10213/6175/9978/6218/5216/6209/6193/6714/6173/6210/6231/6229/11224/6205/6165/5566/6130/6142/6167/6204/5701/6228/23521/116832/1981/140801/6156/6235/6143/5710/6181/6124/8453/6207/9939/6139/5704/6233/7311/6223/25873/1630/3921/6188/6189/9775/6135/6201/6161/9045/6187/6168/22916/5693/6208/6157/6137/6170/200916/6122/6133/7314/5879/6230 111 Cucumber_mosaic_virus R-HSA-8868773 rRNA processing in the nucleus and cytosol 104/1181 195/10654 7.62558497019576e-49 3.225622442392806e-47 1.3940104454287686e-47 6158/6138/6144/2091/6203/6227/9349/4736/6206/6194/6234/22803/6191/54433/6166/6128/51121/6132/6147/6159/6129/6217/6222/6176/6152/6136/10528/6125/4839/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/55272/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/9790/51077/140801/6156/117246/10171/6235/5822/6143/6181/6124/6207/6139/6233/7311/6223/25873/83732/27341/3921/6188/6189/51010/6135/6201/6161/56915/1453/9045/6187/4691/6168/6208/54512/6157/6137/6170/22984/200916/6122/6133/9188/6230 104 Cucumber_mosaic_virus R-HSA-72766 Translation 129/1181 291/10654 1.02460414673542e-48 4.194266652281445e-47 1.8126273699461928e-47 6158/8669/6138/6144/6203/6182/6227/9349/4736/51253/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/1917/1938/6147/6159/8666/6129/1915/6217/1936/6222/1650/1983/6176/6152/6136/8668/27068/8667/6125/1937/6727/6224/6146/51065/6154/8662/6141/10480/6184/26986/6202/6123/6232/58477/6134/6169/6160/6164/6155/63931/8661/6175/6218/9669/1933/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/23107/8894/1981/140801/6156/6235/6143/1973/6181/6124/6185/6207/1977/6139/6233/1975/64975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/10667/6135/6201/1978/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 129 Cucumber_mosaic_virus R-HSA-162906 HIV Infection 114/1181 233/10654 1.800269567214762e-48 7.13919400248604e-47 3.085330409601615e-47 6884/23165/8945/4928/2963/3837/2237/6917/51606/5434/5440/5684/5903/8065/902/55706/7175/9631/25978/2959/5430/5436/6878/4869/6500/404672/6749/348995/10015/79023/57122/5705/5441/23636/5438/3981/10762/5431/7469/23511/5435/4686/7316/10213/9978/5433/2960/53371/920/292/4331/4836/51271/23279/4927/9688/8148/2966/8731/79902/6879/9150/2962/9883/5701/2958/5437/8812/23225/8815/2965/2534/27183/905/5710/2068/5439/2071/5901/8086/5478/6827/5704/6233/2968/1025/7311/9972/2967/3932/6908/8021/11198/129401/904/7936/6829/1104/51497/2547/6882/2961/1022/5432/55746/22916/5693/8178/8480/6877/2957/7314/5879/25920 114 Cucumber_mosaic_virus R-HSA-674695 RNA Polymerase II Pre-transcription Events 66/1181 84/10654 2.2802562291959683e-47 8.768621681362678e-46 3.7895167317738415e-46 6884/85403/2963/6917/5434/5440/902/6830/2959/5430/5436/9646/6878/404672/79577/6749/5441/5438/5431/7469/5435/4686/5433/2960/4331/8148/2966/6879/9150/2962/4298/54623/2958/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/23168/55677/2967/27125/6908/11198/904/7936/6829/51497/6882/4300/2961/1022/5432/22916/8178/55840/6877/80349/2957/123169/25920 66 Cucumber_mosaic_virus R-HSA-72312 rRNA processing 105/1181 205/10654 4.3170188362824956e-47 1.6112637950713194e-45 6.96336474830706e-46 6158/6138/6144/2091/6203/6227/9349/4736/6206/6194/6234/22803/6191/54433/6166/6128/51121/6132/6147/6159/6129/6217/3028/6222/6176/6152/6136/10528/6125/4839/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/55272/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/9790/51077/140801/6156/117246/10171/6235/5822/6143/6181/6124/6207/6139/6233/7311/6223/25873/83732/27341/3921/6188/6189/51010/6135/6201/6161/56915/1453/9045/6187/4691/6168/6208/54512/6157/6137/6170/22984/200916/6122/6133/9188/6230 105 Cucumber_mosaic_virus R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 49/1181 51/10654 6.473938438362919e-45 2.347265108080727e-43 1.0144126094397236e-43 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/8668/8667/6224/51065/8662/10480/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/6204/8663/6228/8894/6235/6207/6233/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1968/6230 49 Cucumber_mosaic_virus R-HSA-112382 Formation of RNA Pol II elongation complex 54/1181 61/10654 1.7555770272898916e-44 6.021154723326683e-43 2.6021497331949745e-43 85403/2963/6917/5434/5440/902/6830/5430/5436/9646/404672/79577/6749/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/4298/54623/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/23168/55677/2967/27125/11198/904/7936/6829/51497/4300/1022/5432/22916/8178/55840/80349/123169/25920 54 Cucumber_mosaic_virus R-HSA-75955 RNA Polymerase II Transcription Elongation 54/1181 61/10654 1.7555770272898916e-44 6.021154723326683e-43 2.6021497331949745e-43 85403/2963/6917/5434/5440/902/6830/5430/5436/9646/404672/79577/6749/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/4298/54623/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/23168/55677/2967/27125/11198/904/7936/6829/51497/4300/1022/5432/22916/8178/55840/80349/123169/25920 54 Cucumber_mosaic_virus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 52/1181 65/10654 3.00464568695701e-38 1.0033935201969593e-36 4.33634460638394e-37 2963/6917/5434/5440/4436/8621/902/5430/5436/404672/6749/4292/545/472/5441/5438/5431/7469/5435/5433/4331/2966/9150/2962/9656/5437/8812/2177/2965/51755/905/2068/5439/1111/2071/7157/55215/6827/2968/672/1025/2967/1386/11198/904/7936/6829/51497/1022/5432/8178/25920 52 Cucumber_mosaic_virus R-HSA-70171 Glycolysis 54/1181 71/10654 1.3830338415560394e-37 4.50017934598619e-36 1.9448330133622038e-36 23165/4928/7167/5903/5313/2597/55706/7175/9631/5315/5567/5568/5211/348995/79023/57122/23636/3099/5214/10762/23511/5528/229/53371/5230/23279/4927/9688/79902/5566/26330/5519/9883/2023/226/23225/2821/669/5224/8086/5213/9972/5518/8021/129401/2026/230/5232/55746/2027/8480/5515/5223/5516 54 Cucumber_mosaic_virus R-HSA-167172 Transcription of the HIV genome 54/1181 73/10654 1.7045474482597077e-36 5.407676779603923e-35 2.337024264587652e-35 6884/2963/6917/5434/5440/902/2959/5430/5436/6878/404672/6749/5441/5438/5431/7469/5435/4686/5433/2960/4331/8148/2966/8731/6879/9150/2962/2958/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/2967/6908/11198/904/7936/6829/51497/6882/2961/1022/5432/22916/8178/6877/2957/25920 54 Cucumber_mosaic_virus R-HSA-70326 Glucose metabolism 60/1181 91/10654 8.111963196784241e-36 2.5107515357851713e-34 1.085066193972937e-34 5105/23165/4928/7167/5903/5313/2597/55706/7175/9631/5315/5567/2806/5568/5211/348995/79023/57122/23636/3099/5214/10762/6576/23511/5528/229/53371/5230/23279/4927/9688/79902/5566/26330/5519/5106/9883/2023/226/23225/2821/4190/669/5224/8086/5213/9972/5518/4191/8021/129401/2026/230/5232/55746/2027/8480/5515/5223/5516 60 Cucumber_mosaic_virus R-HSA-2262752 Cellular responses to stress 151/1181 479/10654 1.898615462961108e-35 5.736531005946777e-34 2.4791445017612466e-34 1017/23165/818/3303/7014/84617/4928/815/51606/1019/5684/5903/5601/573/55706/7175/5606/9631/112399/7531/1915/389541/79726/817/5594/3308/84335/58528/7295/5925/3091/830/7013/7277/348995/1051/10013/545/79023/472/10381/57122/5705/23636/192670/7278/3313/153129/112714/1780/10762/7001/847/23511/7316/10213/9978/890/53371/6774/5970/1026/1639/832/6667/2289/9588/23279/4927/9688/7415/6647/8994/79902/64223/7322/9883/1432/2932/5701/1387/4683/10325/57805/84219/7846/3310/23225/113457/8649/3309/3320/5602/2033/1021/10376/6195/25824/6009/5710/3301/816/192669/7157/8453/8086/10963/4001/5609/10542/5704/6233/3326/2475/55004/3306/7311/367/9972/538/10383/10670/23411/84790/8021/8726/55662/6197/5599/129401/5600/3312/201163/26523/5052/405/64121/57521/55746/5693/2288/5034/8480/10728/829/7314/23523/28956/5595/2950/4193 151 Cucumber_mosaic_virus R-HSA-8953897 Cellular responses to external stimuli 152/1181 493/10654 1.98550678444298e-34 5.8595537429259106e-33 2.5323109784450248e-33 1017/23165/818/3303/7014/84617/4928/815/51606/1019/5684/5903/5601/573/55706/7175/5606/9631/112399/7531/1915/389541/79726/817/5594/3308/84335/58528/7295/5925/3091/830/7013/7277/348995/1051/10013/545/79023/472/10381/57122/5705/23636/192670/7278/3313/153129/112714/1780/10762/7001/847/23511/7316/10213/9978/1465/890/53371/6774/5970/1026/1639/832/6667/2289/9588/23279/4927/9688/7415/6647/8994/79902/64223/7322/9883/1432/2932/5701/1387/4683/10325/57805/84219/7846/3310/23225/113457/8649/3309/3320/5602/2033/1021/10376/6195/25824/6009/5710/3301/816/192669/7157/8453/8086/10963/4001/5609/10542/5704/6233/3326/2475/55004/3306/7311/367/9972/538/10383/10670/23411/84790/8021/8726/55662/6197/5599/129401/5600/3312/201163/26523/5052/405/64121/57521/55746/5693/2288/5034/8480/10728/829/7314/23523/28956/5595/2950/4193 152 Cucumber_mosaic_virus R-HSA-1169408 ISG15 antiviral mechanism 52/1181 72/10654 2.635486809182405e-34 7.600983547391982e-33 3.284901022928309e-33 23165/4928/3837/3838/5903/5335/55706/7175/9631/348995/9636/317649/79023/57122/23636/25820/1982/7706/10762/9470/23511/7316/2317/53371/4734/6772/23279/4927/9688/79902/8672/9883/23225/1981/1973/8086/9246/1977/51191/6233/7311/9972/5300/8021/9775/129401/55746/5495/1974/8480/7314/5595 52 Cucumber_mosaic_virus R-HSA-3371556 Cellular response to heat stress 58/1181 89/10654 3.1128679071902733e-34 8.778287498276571e-33 3.793693987476333e-33 23165/818/3303/4928/815/5903/573/55706/7175/9631/7531/1915/817/5594/3308/84335/348995/10013/545/79023/472/57122/23636/3313/10762/23511/53371/23279/4927/9688/7415/79902/64223/9883/2932/1387/57805/3310/23225/3309/3320/2033/816/8086/3326/2475/3306/9972/23411/8021/129401/3312/57521/55746/2288/8480/10728/5595 58 Cucumber_mosaic_virus R-HSA-168325 Viral Messenger RNA Synthesis 39/1181 43/10654 2.502271065134919e-33 6.903004307948287e-32 2.983256807632249e-32 23165/4928/2963/5434/5440/5903/55706/7175/9631/5430/5436/348995/79023/57122/5441/23636/5438/10762/5431/23511/5435/5433/53371/23279/4927/9688/79902/2962/9883/5437/23225/5439/8086/9972/8021/129401/5432/55746/8480 39 Cucumber_mosaic_virus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 98/1181 244/10654 1.1261094151595193e-32 3.0404954209307024e-31 1.3140044911491817e-31 23165/23451/4928/2963/6635/5434/5440/5903/6633/220988/6432/8683/55706/7175/10946/9631/7884/27339/80145/5430/79869/4904/5436/51585/6428/3184/8106/10212/51503/3178/348995/79023/57122/5441/23636/3183/5438/79622/10762/5431/5093/23511/5435/10594/4686/6625/5433/53371/1655/9343/3190/56339/23279/4927/9688/79902/2962/22938/988/9883/10236/5437/4670/23225/10189/10482/10949/3181/5439/1660/8086/9939/2521/1977/3191/57721/3187/1665/9972/23524/5094/51593/8021/9775/3192/129401/6427/3312/10291/5432/55746/22916/5725/1479/11100/8480/10992/1994 98 Cucumber_mosaic_virus R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 41/1181 48/10654 1.2385429399749448e-32 3.27439789755876e-31 1.4150896309801453e-31 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/22916/8178/25920 41 Cucumber_mosaic_virus R-HSA-113418 Formation of the Early Elongation Complex 33/1181 33/10654 2.0040244283913347e-32 5.086213999257207e-31 2.198098373035548e-31 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/2967/7936/6829/51497/1022/5432/22916/25920 33 Cucumber_mosaic_virus R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 33/1181 33/10654 2.0040244283913347e-32 5.086213999257207e-31 2.198098373035548e-31 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/2967/7936/6829/51497/1022/5432/22916/25920 33 Cucumber_mosaic_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 53/1181 80/10654 6.389405320453444e-32 1.5898343826775337e-30 6.870753708888017e-31 23165/4928/3837/3838/5903/5335/55706/7175/9631/2316/348995/9636/317649/79023/57122/23636/25820/1982/7706/10762/9470/23511/7316/2317/53371/4734/6772/23279/4927/9688/79902/8672/9883/23225/1981/1973/8086/9246/1977/51191/6233/7311/9972/5300/8021/9775/129401/55746/5495/1974/8480/7314/5595 53 Cucumber_mosaic_virus R-HSA-9006925 Intracellular signaling by second messengers 110/1181 305/10654 1.2778861955037183e-31 3.118533811719651e-30 1.3477301778490633e-30 5295/818/5170/27161/815/3838/5684/5290/3667/5335/6801/2309/5468/842/5567/389541/817/10273/207/5578/5594/84335/5568/84232/7249/5582/58528/1460/114/5705/6199/108/192670/2260/153129/5528/2100/7316/10213/107/1457/1026/4734/10645/6714/2099/1108/2122/11060/64223/5566/84254/10014/5519/2932/5701/10325/8649/2534/5728/6009/5710/2264/816/3630/192669/3066/3065/7157/1107/5987/7189/5371/208/10542/5704/6233/2885/79109/2475/55004/1385/7311/3932/2931/5518/1386/10670/1956/5581/8726/808/115/26523/801/64121/57521/5693/814/109/5156/7314/5879/253260/28956/5595/4193/805/5515/5516 110 Cucumber_mosaic_virus R-HSA-167169 HIV Transcription Elongation 39/1181 46/10654 7.783019560815388e-31 1.7957548768499507e-29 7.760675963990081e-30 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/22916/8178/25920 39 Cucumber_mosaic_virus R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 39/1181 46/10654 7.783019560815388e-31 1.7957548768499507e-29 7.760675963990081e-30 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/22916/8178/25920 39 Cucumber_mosaic_virus R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 39/1181 46/10654 7.783019560815388e-31 1.7957548768499507e-29 7.760675963990081e-30 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/22916/8178/25920 39 Cucumber_mosaic_virus R-HSA-5663202 Diseases of signal transduction 123/1181 377/10654 1.8695387227996745e-30 4.236508284344262e-29 1.8308828469523129e-29 5295/8454/4000/818/5170/2963/815/5434/5440/5684/5290/3667/5335/71/6801/2309/1499/892/842/5430/817/207/5436/1452/5594/84335/7249/6500/10013/5705/5441/6199/2260/5438/5431/5528/2100/5435/4686/7316/10213/9978/5433/3714/6774/9759/1026/6772/6714/2099/5605/4609/5664/7415/64223/4089/10014/2962/22938/5519/399687/2932/5701/1387/5437/4088/3320/324/2335/2534/2033/55294/5728/1445/5710/5439/2264/816/3066/3065/2280/5894/4087/208/5704/6233/2885/79109/2475/1385/7311/8826/5906/3932/2931/5518/1956/60/4140/7040/808/3845/3265/3516/369/801/4851/5432/22916/5693/5663/11140/5245/7529/5156/7314/5879/253260/5595/4193/805/5515/5516 123 Cucumber_mosaic_virus R-HSA-165159 mTOR signalling 35/1181 40/10654 8.844104666359027e-29 1.968976986247299e-27 8.509286299488556e-28 5563/6194/389541/207/84335/51422/7249/58528/53632/6198/153129/64223/5571/10325/8649/6794/1981/6009/5494/1977/208/10542/1975/2475/55004/5562/10670/1978/5564/5565/64121/57521/7248/7529/28956 35 Cucumber_mosaic_virus R-HSA-72086 mRNA Capping 28/1181 29/10654 3.485804179328109e-26 7.626699144081673e-25 3.2960144780942736e-25 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/4686/5433/4331/2966/8731/2962/5437/2965/2068/5439/2071/2968/2967/6829/1022/5432/22916 28 Cucumber_mosaic_virus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 31/1181 35/10654 5.752874075240239e-26 1.237355457877943e-24 5.34745297627148e-25 23165/4928/5903/55706/7175/9631/7884/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/1977/9972/8021/129401/55746/22916/8480 31 Cucumber_mosaic_virus R-HSA-167161 HIV Transcription Initiation 36/1181 47/10654 1.2991467009946775e-25 2.5363340977880705e-24 1.096122155818991e-24 6884/2963/5434/5440/902/2959/5430/5436/6878/404672/5441/5438/5431/5435/5433/2960/4331/8148/2966/6879/2962/2958/5437/2965/2068/5439/2071/2968/2967/6908/6882/2961/1022/5432/6877/2957 36 Cucumber_mosaic_virus R-HSA-167162 RNA Polymerase II HIV Promoter Escape 36/1181 47/10654 1.2991467009946775e-25 2.5363340977880705e-24 1.096122155818991e-24 6884/2963/5434/5440/902/2959/5430/5436/6878/404672/5441/5438/5431/5435/5433/2960/4331/8148/2966/6879/2962/2958/5437/2965/2068/5439/2071/2968/2967/6908/6882/2961/1022/5432/6877/2957 36 Cucumber_mosaic_virus R-HSA-73776 RNA Polymerase II Promoter Escape 36/1181 47/10654 1.2991467009946775e-25 2.5363340977880705e-24 1.096122155818991e-24 6884/2963/5434/5440/902/2959/5430/5436/6878/404672/5441/5438/5431/5435/5433/2960/4331/8148/2966/6879/2962/2958/5437/2965/2068/5439/2071/2968/2967/6908/6882/2961/1022/5432/6877/2957 36 Cucumber_mosaic_virus R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 36/1181 47/10654 1.2991467009946775e-25 2.5363340977880705e-24 1.096122155818991e-24 6884/2963/5434/5440/902/2959/5430/5436/6878/404672/5441/5438/5431/5435/5433/2960/4331/8148/2966/6879/2962/2958/5437/2965/2068/5439/2071/2968/2967/6908/6882/2961/1022/5432/6877/2957 36 Cucumber_mosaic_virus R-HSA-75953 RNA Polymerase II Transcription Initiation 36/1181 47/10654 1.2991467009946775e-25 2.5363340977880705e-24 1.096122155818991e-24 6884/2963/5434/5440/902/2959/5430/5436/6878/404672/5441/5438/5431/5435/5433/2960/4331/8148/2966/6879/2962/2958/5437/2965/2068/5439/2071/2968/2967/6908/6882/2961/1022/5432/6877/2957 36 Cucumber_mosaic_virus R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 36/1181 47/10654 1.2991467009946775e-25 2.5363340977880705e-24 1.096122155818991e-24 6884/2963/5434/5440/902/2959/5430/5436/6878/404672/5441/5438/5431/5435/5433/2960/4331/8148/2966/6879/2962/2958/5437/2965/2068/5439/2071/2968/2967/6908/6882/2961/1022/5432/6877/2957 36 Cucumber_mosaic_virus R-HSA-159227 Transport of the SLBP independent Mature mRNA 30/1181 34/10654 4.703787884340622e-25 9.044101250345831e-24 3.9085701558875024e-24 23165/4928/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/1977/9972/8021/129401/55746/22916/8480 30 Cucumber_mosaic_virus R-HSA-438064 Post NMDA receptor activation events 47/1181 81/10654 9.78192391680737e-25 1.8527255896162017e-23 8.006885091369426e-24 818/5170/5563/84617/815/3838/28964/5567/817/5594/5568/51422/7277/114/53632/10381/7278/112714/107/10645/6714/5566/84254/5571/7846/113457/10376/6195/4137/816/1385/5562/10383/84790/8874/808/6197/3845/3265/5564/801/5565/814/4747/5879/5595/805 47 Cucumber_mosaic_virus R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 26/1181 27/10654 2.750421574815464e-24 5.0583840267258315e-23 2.1860711525230464e-23 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/5433/4331/2966/8731/2962/5437/2965/2068/5439/2071/2968/2967/6829/1022/5432 26 Cucumber_mosaic_virus R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 26/1181 27/10654 2.750421574815464e-24 5.0583840267258315e-23 2.1860711525230464e-23 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/5433/4331/2966/8731/2962/5437/2965/2068/5439/2071/2968/2967/6829/1022/5432 26 Cucumber_mosaic_virus R-HSA-180746 Nuclear import of Rev protein 29/1181 33/10654 3.8285800034917065e-24 6.940668606329966e-23 2.9995341079987656e-23 23165/4928/3837/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/9972/8021/129401/1104/55746/8480 29 Cucumber_mosaic_virus R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 23/1181 23/10654 8.823538673253616e-23 1.5770521938533577e-21 6.815513193128441e-22 2963/5434/5440/5430/5436/5441/5438/5431/7469/5435/4686/5433/9150/2962/5437/5439/6827/7936/6829/51497/5432/22916/25920 23 Cucumber_mosaic_virus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 41/1181 69/10654 2.753809028645732e-22 4.853588412988103e-21 2.097565064216998e-21 23165/3303/4928/5903/573/55706/7175/9631/7531/5594/3308/348995/545/79023/472/57122/23636/3313/10762/23511/53371/23279/4927/9688/79902/9883/2932/57805/3310/23225/3309/8086/3306/9972/23411/8021/129401/3312/55746/8480/5595 41 Cucumber_mosaic_virus R-HSA-442755 Activation of NMDA receptors and postsynaptic events 48/1181 93/10654 3.1786071365567313e-22 5.5255513099869756e-21 2.387965851688619e-21 818/5170/5563/84617/815/3838/8573/28964/5567/817/5594/5568/51422/7277/114/53632/10381/7278/112714/107/10645/6714/5566/84254/5571/7846/113457/10376/6195/4137/816/1385/5562/10383/84790/8874/808/6197/3845/3265/5564/801/5565/814/4747/5879/5595/805 48 Cucumber_mosaic_virus R-HSA-1257604 PIP3 activates AKT signaling 87/1181 264/10654 4.6403533695952405e-22 7.957578954076162e-21 3.4390101074809686e-21 5295/5170/27161/5684/5290/3667/6801/2309/5468/842/389541/10273/207/5594/84335/84232/7249/58528/1460/5705/6199/192670/2260/153129/5528/2100/7316/10213/1457/1026/4734/6714/2099/1108/2122/11060/64223/10014/5519/2932/5701/10325/8649/2534/5728/6009/5710/2264/3630/192669/3066/3065/7157/1107/5987/7189/5371/208/10542/5704/6233/2885/79109/2475/55004/1385/7311/3932/2931/5518/1386/10670/1956/8726/26523/64121/57521/5693/5156/7314/5879/253260/28956/5595/4193/5515/5516 87 Cucumber_mosaic_virus R-HSA-167287 HIV elongation arrest and recovery 29/1181 36/10654 5.603328770169165e-22 9.234576895252818e-21 3.990887613476602e-21 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/7469/5435/5433/9150/2962/5437/8812/905/5439/6827/1025/11198/904/7936/6829/51497/5432/8178/25920 29 Cucumber_mosaic_virus R-HSA-167290 Pausing and recovery of HIV elongation 29/1181 36/10654 5.603328770169165e-22 9.234576895252818e-21 3.990887613476602e-21 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/7469/5435/5433/9150/2962/5437/8812/905/5439/6827/1025/11198/904/7936/6829/51497/5432/8178/25920 29 Cucumber_mosaic_virus R-HSA-177243 Interactions of Rev with host cellular proteins 29/1181 36/10654 5.603328770169165e-22 9.234576895252818e-21 3.990887613476602e-21 23165/4928/3837/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/9972/8021/129401/1104/55746/8480 29 Cucumber_mosaic_virus R-HSA-5633007 Regulation of TP53 Activity 64/1181 160/10654 1.5076450515421758e-21 2.4528225261628477e-20 1.0600311361045527e-20 6884/1017/5170/5563/6446/8445/207/6878/51422/1460/6749/11200/545/472/53632/117584/580/7316/890/84289/1457/983/1108/8148/64223/6879/5519/1432/5571/4683/6794/2033/84126/1111/3066/3065/7157/1107/5984/5371/208/6233/79109/2475/672/7311/5562/5518/6908/8851/5300/5983/11198/5600/5564/6882/5565/1020/6877/7314/253260/4193/5515/5516 64 Cucumber_mosaic_virus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 31/1181 42/10654 2.165933877568755e-21 3.479202646373101e-20 1.5035996671729797e-20 23165/4928/5903/55706/7175/9631/7884/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/1977/9972/8021/129401/55746/22916/8480 31 Cucumber_mosaic_virus R-HSA-71291 Metabolism of amino acids and derivatives 106/1181 372/10654 4.206276266254854e-21 6.672205727346763e-20 2.8835130719983935e-20 6158/440/4967/6138/6144/6203/5684/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6147/6159/6129/5160/6217/3028/2806/6222/8659/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/5705/6232/6134/6169/6160/6164/6155/10213/6175/6218/9380/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/5701/6228/23521/116832/445/6999/5162/140801/6156/6235/6143/5710/6181/6124/26227/6207/6139/5704/6233/7311/6223/25873/4706/1738/3921/6188/6189/6135/6201/6161/4357/2653/9045/6187/6168/5693/6208/6157/6137/6170/200916/6122/6133/6230 106 Cucumber_mosaic_virus R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 27/1181 33/10654 7.052826117454761e-21 1.104942758401246e-19 4.775207806619793e-20 23165/3303/4928/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/9972/8021/129401/55746/8480 27 Cucumber_mosaic_virus R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 26/1181 31/10654 1.1124084905222574e-20 1.7007787644249936e-19 7.350219702753279e-20 23165/4928/3837/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 26 Cucumber_mosaic_virus R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 26/1181 31/10654 1.1124084905222574e-20 1.7007787644249936e-19 7.350219702753279e-20 23165/4928/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/9972/8021/129401/55746/8480 26 Cucumber_mosaic_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 123/1181 473/10654 1.2227378326035063e-20 1.8472075113974399e-19 7.983037729153216e-20 5295/5170/2963/51606/5434/5440/5590/9252/8065/857/5290/3667/5335/71/5579/1495/1499/5340/5567/5430/10273/207/5436/1849/5578/5594/5568/1785/3315/3178/51741/5441/2260/5438/348/5431/5528/5435/4686/7316/5433/6774/4205/5289/4734/10413/10152/6772/6714/2099/5605/5664/64223/5566/8569/2962/5519/1432/4208/5437/4670/4914/9146/3320/2335/2534/64759/4846/6195/1445/5439/1111/2264/5603/3630/7072/3925/6285/208/30011/6233/2885/7525/3187/79109/2475/23191/1385/7311/5906/3932/5518/2185/1213/1956/60/8851/5581/8874/808/6197/3845/5600/3265/6300/801/1020/5432/22916/5663/5725/11140/7529/5156/7314/5879/253260/5595/805/5515/25920/5516/5607 123 Cucumber_mosaic_virus R-HSA-2980766 Nuclear Envelope Breakdown 34/1181 52/10654 1.2572328249011417e-20 1.8769746527053516e-19 8.111681755708914e-20 4000/23165/4928/5903/55706/7175/5579/9631/5578/348995/79023/57122/23636/10762/23511/891/53371/983/23279/4927/9688/79902/9883/23225/8815/8086/2010/4001/9972/8021/129401/55746/7112/8480 34 Cucumber_mosaic_virus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 30/1181 41/10654 1.4761860698324138e-20 2.178232700717829e-19 9.413622305785649e-20 23165/4928/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/1977/9972/8021/129401/55746/22916/8480 30 Cucumber_mosaic_virus R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK 25/1181 29/10654 1.5973483188689898e-20 2.329925306488216e-19 1.0069189039694418e-19 5563/389541/51422/7249/58528/53632/153129/64223/5571/10325/8649/6794/6009/5494/10542/2475/55004/5562/10670/5564/5565/64121/57521/7248/28956 25 Cucumber_mosaic_virus R-HSA-166208 mTORC1-mediated signalling 22/1181 23/10654 1.667549839441015e-20 2.404682666193918e-19 1.0392266343884797e-19 6194/389541/84335/58528/6198/153129/64223/10325/8649/1981/6009/1977/10542/1975/2475/55004/10670/1978/64121/57521/7529/28956 22 Cucumber_mosaic_virus R-HSA-165054 Rev-mediated nuclear export of HIV RNA 27/1181 34/10654 3.0670804641009517e-20 4.2770605592792394e-19 1.8484082380527426e-19 23165/4928/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/9972/8021/129401/1104/55746/8480 27 Cucumber_mosaic_virus R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 27/1181 34/10654 3.0670804641009517e-20 4.2770605592792394e-19 1.8484082380527426e-19 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/7469/5435/5433/9150/2962/5437/5439/6827/1025/11198/904/7936/6829/51497/5432/8178/25920 27 Cucumber_mosaic_virus R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 27/1181 34/10654 3.0670804641009517e-20 4.2770605592792394e-19 1.8484082380527426e-19 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/7469/5435/5433/9150/2962/5437/5439/6827/1025/11198/904/7936/6829/51497/5432/8178/25920 27 Cucumber_mosaic_virus R-HSA-168253 Host Interactions with Influenza Factors 30/1181 42/10654 4.625167775021277e-20 6.3797151157630435e-19 2.7571080214943765e-19 23165/4928/3837/3838/5903/55706/7175/9631/8106/348995/9636/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/7040/129401/55746/8480 30 Cucumber_mosaic_virus R-HSA-168276 NS1 Mediated Effects on Host Pathways 29/1181 40/10654 9.967076018300209e-20 1.3600235986261252e-18 5.87758529205932e-19 23165/4928/3837/3838/5903/55706/7175/9631/8106/348995/9636/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 29 Cucumber_mosaic_virus R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 27/1181 35/10654 1.2014002168355787e-19 1.6218902927280313e-18 7.009289059029525e-19 23165/4928/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/891/53371/983/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 27 Cucumber_mosaic_virus R-HSA-162909 Host Interactions of HIV factors 54/1181 129/10654 1.9087642646335758e-19 2.5497072124421134e-18 1.101901586564092e-18 23165/8945/4928/3837/51606/5684/5903/8065/55706/7175/9631/4869/6500/348995/79023/57122/5705/23636/10762/23511/7316/10213/9978/53371/920/292/23279/4927/9688/79902/9883/5701/23225/8815/2534/5710/5901/8086/5478/5704/6233/1025/7311/9972/3932/8021/129401/904/1104/55746/5693/8480/7314/5879 54 Cucumber_mosaic_virus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 28/1181 38/10654 2.0992766346071437e-19 2.774981301371318e-18 1.1992578142876337e-18 23165/4928/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/5987/5371/9972/8021/129401/55746/8480/4193 28 Cucumber_mosaic_virus R-HSA-180910 Vpr-mediated nuclear import of PICs 26/1181 33/10654 2.242359862028864e-19 2.9335615102212664e-18 1.2677910885697646e-18 23165/4928/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8815/8086/9972/8021/129401/55746/8480 26 Cucumber_mosaic_virus R-HSA-5628897 TP53 Regulates Metabolic Genes 43/1181 86/10654 2.385502940086051e-19 3.08898288874408e-18 1.3349592178139983e-18 27161/5563/7531/389541/207/10971/51422/7249/58528/7295/53632/192670/7534/153129/7001/2539/64223/5571/10325/2821/8649/10128/5728/25824/6009/192669/7157/208/10542/2475/55004/5562/10670/4697/26523/5564/5052/5565/64121/57521/7248/7529/28956 43 Cucumber_mosaic_virus R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 25/1181 31/10654 3.9706150122407515e-19 5.0387104505335135e-18 2.177568864607823e-18 23165/4928/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 25 Cucumber_mosaic_virus R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 25/1181 31/10654 3.9706150122407515e-19 5.0387104505335135e-18 2.177568864607823e-18 23165/4928/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 25 Cucumber_mosaic_virus R-HSA-429914 Deadenylation-dependent mRNA decay 34/1181 56/10654 4.0523244181052677e-19 5.091484838193648e-18 2.20037626037816e-18 1656/9924/80153/23644/5073/27257/4849/4850/255967/26986/10605/28960/9337/25904/246175/4848/23019/1981/1973/1977/1975/55571/9775/51010/54464/6499/57472/56915/85456/29883/54512/1974/167227/80349 34 Cucumber_mosaic_virus R-HSA-176033 Interactions of Vpr with host cellular proteins 27/1181 36/10654 4.302645874594732e-19 5.352997661628152e-18 2.3133937055354544e-18 23165/4928/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/292/23279/4927/9688/79902/9883/23225/8815/8086/9972/8021/129401/55746/8480 27 Cucumber_mosaic_virus R-HSA-4085377 SUMOylation of SUMOylation proteins 26/1181 34/10654 8.533228262789899e-19 1.0513268607262505e-17 4.543497112839589e-18 23165/4928/5903/55706/7175/9631/348995/79023/6613/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 26 Cucumber_mosaic_virus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 33/1181 54/10654 1.0175692294888698e-18 1.2416301463667075e-17 5.365926807324911e-18 6917/5434/5440/902/27339/5430/5436/404672/5441/5438/5431/8450/5435/7316/9978/5433/4331/2966/5437/2965/2033/2068/5439/10987/2071/6233/2968/7311/2967/1022/5432/7314/8451 33 Cucumber_mosaic_virus R-HSA-72163 mRNA Splicing - Major Pathway 65/1181 183/10654 1.181113488459321e-18 1.4274600160522652e-17 6.169023834459211e-18 23451/2963/6635/5434/5440/6633/220988/6432/8683/10946/27339/5430/79869/4904/5436/51585/6428/3184/8106/51503/3178/5441/3183/5438/5431/5093/5435/10594/4686/6625/5433/1655/9343/3190/2962/22938/988/10236/5437/4670/10189/10949/3181/5439/1660/9939/2521/3191/3187/1665/23524/5094/51593/9775/3192/6427/3312/10291/5432/22916/5725/1479/11100/10992/1994 65 Cucumber_mosaic_virus R-HSA-429947 Deadenylation of mRNA 22/1181 25/10654 1.3379875981293156e-18 1.6017983604019825e-17 6.922458179000729e-18 9924/5073/4849/4850/255967/26986/10605/9337/25904/246175/4848/23019/1981/1973/1977/1975/55571/9775/57472/85456/29883/1974 22 Cucumber_mosaic_virus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 36/1181 65/10654 2.5435375793874472e-18 3.016588026395019e-17 1.3036724828931235e-17 6917/5434/5440/902/27339/5430/5436/404672/54107/5441/5438/5431/8450/5435/7316/9978/5433/4331/5111/2966/5437/2965/2033/2068/5439/2071/5984/6233/2968/7311/2967/5983/1022/5432/7314/8451 36 Cucumber_mosaic_virus R-HSA-72172 mRNA Splicing 66/1181 191/10654 3.3320574551485977e-18 3.9151675097996023e-17 1.6920096823902725e-17 23451/2963/6635/5434/5440/6633/220988/6432/8683/10946/27339/5430/79869/4904/5436/51585/6428/3184/8106/51503/3178/5441/3183/5438/79622/5431/5093/5435/10594/4686/6625/5433/1655/9343/3190/2962/22938/988/10236/5437/4670/10189/10949/3181/5439/1660/9939/2521/3191/3187/1665/23524/5094/51593/9775/3192/6427/3312/10291/5432/22916/5725/1479/11100/10992/1994 66 Cucumber_mosaic_virus R-HSA-9612973 Autophagy 50/1181 119/10654 3.508101892249294e-18 4.084203028682893e-17 1.7650614059506345e-17 5563/25978/1915/389541/8878/60673/9821/51422/7249/58528/1080/1460/10013/53632/153129/9474/7316/5289/1457/51271/8678/6714/64223/8408/5571/3920/10325/8649/3320/6009/9776/55054/10542/6233/3326/2475/55004/7311/5562/10670/7431/3312/5564/11315/5565/64121/57521/7248/7314/28956 50 Cucumber_mosaic_virus R-HSA-6782135 Dual incision in TC-NER 36/1181 66/10654 5.0087061858179985e-18 5.73088624655216e-17 2.4767050180031316e-17 6917/5434/5440/902/27339/5430/5436/404672/54107/5441/5438/5431/8450/5435/7316/9978/5433/4331/5111/2966/5437/2965/2033/2068/5439/2071/5984/6233/2968/7311/2967/5983/1022/5432/7314/8451 36 Cucumber_mosaic_virus R-HSA-5654738 Signaling by FGFR2 38/1181 73/10654 5.012831941428604e-18 5.73088624655216e-17 2.4767050180031316e-17 5295/2963/5434/5440/5290/5335/5430/5436/5594/3178/5441/5438/5431/5435/4686/7316/5433/6714/8569/2962/5437/4670/5439/7072/6233/2885/3187/7311/5518/3845/3265/5432/22916/5725/7314/5595/5515/5516 38 Cucumber_mosaic_virus R-HSA-191859 snRNP Assembly 32/1181 53/10654 5.751674958941114e-18 6.459181878669269e-17 2.791451004758566e-17 23165/4928/6635/5903/6633/55706/7175/9631/25929/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/51808/23225/79084/8086/9972/8021/129401/55746/22916/8480 32 Cucumber_mosaic_virus R-HSA-194441 Metabolism of non-coding RNA 32/1181 53/10654 5.751674958941114e-18 6.459181878669269e-17 2.791451004758566e-17 23165/4928/6635/5903/6633/55706/7175/9631/25929/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/51808/23225/79084/8086/9972/8021/129401/55746/22916/8480 32 Cucumber_mosaic_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 43/1181 92/10654 6.255362088929196e-18 6.963205693729078e-17 3.009273913510721e-17 6884/1017/5563/8445/6878/51422/1460/6749/11200/545/472/53632/580/7316/890/1457/8148/6879/1432/5571/4683/6794/84126/1111/7157/5984/6233/672/7311/5562/6908/8851/5300/5983/11198/5600/5564/6882/5565/1020/6877/7314/4193 43 Cucumber_mosaic_virus R-HSA-913531 Interferon Signaling 67/1181 199/10654 8.750446633520285e-18 9.655927632988906e-17 4.1729818728275225e-17 23165/818/4928/815/3837/3838/5903/5335/55706/7175/9631/7412/2316/817/9830/3123/348995/9636/317649/79023/57122/23636/25820/1982/7706/10762/9470/23511/4684/7316/3122/2317/53371/103/4734/6772/23279/4927/9688/79902/8672/9883/23225/1981/1973/816/8086/10346/9246/1977/5371/51191/6233/7311/9972/5300/8021/9775/129401/55746/3105/3660/5495/1974/8480/7314/5595 67 Cucumber_mosaic_virus R-HSA-4615885 SUMOylation of DNA replication proteins 29/1181 45/10654 1.6032422767446388e-17 1.7538917665421955e-16 7.579757043411586e-17 23165/4928/5903/55706/7175/55143/9631/348995/79023/6613/57122/23636/10762/23511/53371/5111/23279/4927/9688/79902/9883/23225/8086/9972/6612/8021/129401/55746/8480 29 Cucumber_mosaic_virus R-HSA-8939211 ESR-mediated signaling 71/1181 223/10654 2.819612361890374e-17 3.058194946358021e-16 1.3216536577101976e-16 5295/5170/27161/2963/3838/5434/5440/5590/857/5290/6801/2309/5430/207/5436/5451/5594/6722/3315/5441/192670/5438/5431/5885/2100/5435/5433/1509/5469/1655/6667/2289/6714/2099/4609/2962/2958/1387/5437/3320/2033/4846/9126/595/2783/4602/5439/192669/3065/861/208/3326/1385/1025/1386/6908/1956/5536/808/3845/904/3265/26523/23189/801/5432/2288/10728/2957/5595/805 71 Cucumber_mosaic_virus R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 37/1181 75/10654 1.3900141418202723e-16 1.4948541914999368e-15 6.460279820591988e-16 23165/4928/5903/6432/8683/55706/7175/9631/80145/6428/10212/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/9939/9972/8021/9775/129401/6427/55746/22916/8480 37 Cucumber_mosaic_virus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 38/1181 79/10654 1.5935120804609505e-16 1.699299857231047e-15 7.343828340735561e-16 6917/5434/5440/902/27339/5430/5436/404672/54107/5441/5438/5431/8450/5435/7316/9978/5433/4331/5111/2966/5437/2965/2033/2068/5439/10987/2071/5984/6233/2968/7311/2967/5983/1022/5432/8178/7314/8451 38 Cucumber_mosaic_virus R-HSA-190236 Signaling by FGFR 40/1181 87/10654 1.8551021725524027e-16 1.961770547474166e-15 8.478142385085981e-16 5295/2963/5434/5440/5290/5335/5430/5436/5594/3178/5441/2260/5438/5431/5435/4686/7316/5433/6714/8569/2962/5437/4670/5439/2264/7072/6233/2885/3187/7311/5518/3845/3265/5432/22916/5725/7314/5595/5515/5516 40 Cucumber_mosaic_virus R-HSA-6803529 FGFR2 alternative splicing 21/1181 26/10654 2.8167945509351357e-16 2.954142384410485e-15 1.2766854815460684e-15 2963/5434/5440/5430/5436/3178/5441/5438/5431/5435/4686/5433/2962/5437/4670/5439/7072/3187/5432/22916/5725 21 Cucumber_mosaic_virus R-HSA-72202 Transport of Mature Transcript to Cytoplasm 39/1181 84/10654 2.9257636892930515e-16 3.043273870256461e-15 1.3152052477322519e-15 23165/4928/5903/6432/8683/55706/7175/9631/7884/80145/6428/10212/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/9939/1977/9972/8021/9775/129401/6427/55746/22916/8480 39 Cucumber_mosaic_virus R-HSA-6807070 PTEN Regulation 52/1181 140/10654 4.1086661684332144e-16 4.238940949383536e-15 1.831934166669837e-15 27161/5684/5468/389541/10273/207/5594/84232/58528/1460/5705/192670/153129/7316/10213/1457/4734/1108/2122/11060/64223/10014/5701/10325/8649/5728/6009/5710/192669/3066/3065/7157/1107/5987/5371/208/10542/5704/6233/2475/55004/7311/1386/10670/8726/26523/64121/57521/5693/7314/28956/5595 52 Cucumber_mosaic_virus R-HSA-9619483 Activation of AMPK downstream of NMDARs 22/1181 29/10654 5.846489779484782e-16 5.983222201746927e-15 2.5857565153748484e-15 5563/84617/51422/7277/53632/10381/7278/112714/10645/5571/7846/113457/10376/4137/5562/10383/84790/808/5564/801/5565/805 22 Cucumber_mosaic_virus R-HSA-4570464 SUMOylation of RNA binding proteins 28/1181 47/10654 1.144657565722394e-15 1.1620563607213743e-14 5.022034456769408e-15 23165/4928/5903/55706/7175/9631/348995/79023/6613/57122/23636/3183/10762/23511/53371/3190/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 28 Cucumber_mosaic_virus R-HSA-1632852 Macroautophagy 41/1181 95/10654 1.2297963224484348e-15 1.238580581894495e-14 5.3527475688858354e-15 5563/25978/389541/8878/60673/9821/51422/7249/58528/1460/53632/153129/9474/7316/5289/1457/8678/6714/64223/8408/5571/10325/8649/6009/9776/55054/10542/6233/2475/55004/7311/5562/10670/3312/5564/5565/64121/57521/7248/7314/28956 41 Cucumber_mosaic_virus R-HSA-6804757 Regulation of TP53 Degradation 24/1181 36/10654 3.2023052756777158e-15 3.1997837754606464e-14 1.382843803255773e-14 1017/5170/6446/207/11200/472/117584/7316/890/983/64223/5519/7157/208/6233/79109/2475/7311/5518/7314/253260/4193/5515/5516 24 Cucumber_mosaic_virus R-HSA-5696398 Nucleotide Excision Repair 44/1181 111/10654 4.906202414961901e-15 4.864039737958322e-14 2.1020817912789066e-14 6917/5434/5440/902/27339/5430/5436/404672/54107/6613/5441/86/5438/5431/8450/5435/7316/9978/5433/4331/5111/2966/5437/2965/2033/142/2068/5439/10987/2071/5984/6233/2968/7311/2967/6612/60/8607/5983/1022/5432/8178/7314/8451 44 Cucumber_mosaic_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 59/1181 182/10654 5.875915626441421e-15 5.78026118601098e-14 2.4980432814165486e-14 23165/4928/5893/5903/55706/7175/55143/9631/5468/4869/348995/79023/6613/57122/23636/3183/10762/5885/23511/53371/1655/5970/3190/9759/5111/2099/23279/4927/9688/79902/9656/9883/1387/10521/23225/2033/9126/142/7067/3066/3065/7157/1107/8086/5987/5371/672/7158/10155/367/9972/6612/8021/6294/129401/11315/55746/8480/4193 59 Cucumber_mosaic_virus R-HSA-2990846 SUMOylation 60/1181 188/10654 7.69930291035536e-15 7.515704148646888e-14 3.248046005097282e-14 23165/4928/5893/5903/55706/7175/55143/9631/5468/4869/348995/79023/6613/57122/23636/3183/10762/5885/23511/53371/1655/5970/3190/9759/5111/2099/23279/4927/9688/79902/9656/9883/1387/10521/23225/59343/2033/9126/142/7067/3066/3065/7157/1107/8086/5987/5371/672/7158/10155/367/9972/6612/8021/6294/129401/11315/55746/8480/4193 60 Cucumber_mosaic_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 24/1181 37/10654 8.163127276989518e-15 7.907640087404349e-14 3.417428132833699e-14 1017/5170/6446/207/11200/472/117584/7316/890/983/64223/5519/7157/208/6233/79109/2475/7311/5518/7314/253260/4193/5515/5516 24 Cucumber_mosaic_virus R-HSA-203927 MicroRNA (miRNA) biogenesis 19/1181 24/10654 1.5287208094176617e-14 1.4696565963265247e-13 6.351383905156314e-14 27161/5434/5440/5430/5436/5441/192670/5438/5431/5435/5433/5437/5439/192669/5901/8575/26523/5432/23405 19 Cucumber_mosaic_virus R-HSA-9006931 Signaling by Nuclear Receptors 80/1181 299/10654 1.7798528449047774e-14 1.6982204963790696e-13 7.3391636897142e-14 5295/5105/5170/27161/2963/3838/5434/5440/5590/857/5290/1374/6801/2309/5160/5430/207/5436/5451/5594/6722/3315/5441/8644/192670/5438/348/5431/5885/2100/5435/5433/1509/5469/1655/6667/2289/6714/2099/4609/2962/2958/1387/5437/2171/3320/2033/5162/4846/9126/595/2783/4602/5439/192669/3065/861/208/3326/1385/1025/1738/1386/6908/1956/5536/808/3845/904/3265/26523/23189/801/5432/216/2288/10728/2957/5595/805 80 Cucumber_mosaic_virus R-HSA-73894 DNA Repair 86/1181 334/10654 2.0214516823385937e-14 1.91434491409528e-13 8.273184025910505e-14 1017/7014/124739/25/3838/2237/6917/5434/5440/5893/4436/902/27339/5430/5436/675/63967/404672/54107/7013/4292/9636/11200/545/472/6613/5441/7706/86/5438/3981/580/5431/5591/8450/5435/7316/9978/5433/890/4331/5111/2966/7415/7517/9656/22976/4683/5437/2177/2965/25898/2033/84126/142/2068/5439/1111/10987/2071/7157/55215/5984/9246/6233/2968/672/7158/7311/6047/2967/6612/60/5536/8607/5983/2175/5599/10973/2547/55666/1022/5432/8178/7314/8451 86 Cucumber_mosaic_virus R-HSA-195258 RHO GTPase Effectors 84/1181 327/10654 4.761364577164679e-14 4.4756827025347987e-13 1.9342463506454564e-13 5170/84617/4928/25/5590/5903/1072/54908/71/55143/5579/1495/1499/7531/1058/4659/10093/4627/2316/10971/5578/5594/6722/10627/1080/7277/348995/79023/10381/57122/7278/6232/7534/112714/1780/5528/5501/5289/5585/5216/81624/10094/10152/6714/23279/79902/5519/1432/2017/4637/7846/999/113457/89953/22919/79784/10376/11113/4628/2885/10096/23191/367/8826/5518/3799/10383/103910/60/5300/84790/808/5600/801/9793/10726/55746/5500/7529/5879/5595/805/5515/5516 84 Cucumber_mosaic_virus R-HSA-450294 MAP kinase activation 31/1181 64/10654 7.872684469376833e-14 7.345909258558235e-13 3.17466610568524e-13 8454/8945/5601/9252/5606/1849/5594/6500/5528/7316/4205/5519/1432/4208/5602/6195/10454/7189/5609/6233/1385/7311/5518/1386/6197/5599/5600/7314/5595/5515/5516 31 Cucumber_mosaic_virus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 34/1181 77/10654 1.5032360870921677e-13 1.392413572642307e-12 6.017564359393157e-13 23165/4928/5893/5903/55706/7175/9631/348995/79023/6613/57122/23636/10762/5885/23511/53371/23279/4927/9688/79902/9656/9883/23225/9126/142/8086/5371/672/9972/6612/8021/129401/55746/8480 34 Cucumber_mosaic_virus R-HSA-453279 Mitotic G1-G1/S phases 50/1181 149/10654 1.5822494480342156e-13 1.4549815576488547e-12 6.287963100120719e-13 8454/1017/25/26271/894/1019/5684/4605/902/8317/207/6500/54107/5925/5705/7316/10213/5422/4174/891/890/4331/983/1026/5111/6714/4171/4609/5519/5701/6502/1021/1874/595/5710/3065/896/208/5704/6233/7311/5518/1022/1859/5693/1028/7314/5515/6241/5516 50 Cucumber_mosaic_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 38/1181 94/10654 1.7282299422031827e-13 1.5777869040689486e-12 6.818688374766059e-13 8454/8945/5601/351/9252/5606/1849/5594/6500/841/5528/7316/5970/4205/7322/5519/1432/4208/329/5602/6195/10454/7189/6285/5609/6233/1385/7311/5518/1386/8772/6197/5599/5600/7314/5595/5515/5516 38 Cucumber_mosaic_virus R-HSA-69231 Cyclin D associated events in G1 25/1181 44/10654 1.810404903550347e-13 1.6293644131953123e-12 7.041589807762081e-13 8454/25/894/1019/902/6500/5925/7316/4331/1026/6714/5519/6502/1021/1874/595/896/6233/7311/5518/1022/1028/7314/5515/5516 25 Cucumber_mosaic_virus R-HSA-69236 G1 Phase 25/1181 44/10654 1.810404903550347e-13 1.6293644131953123e-12 7.041589807762081e-13 8454/25/894/1019/902/6500/5925/7316/4331/1026/6714/5519/6502/1021/1874/595/896/6233/7311/5518/1022/1028/7314/5515/5516 25 Cucumber_mosaic_virus R-HSA-4420097 VEGFA-VEGFR2 Pathway 39/1181 99/10654 2.245871514935828e-13 2.0070499665165956e-12 8.673825495044969e-13 5295/5170/5590/857/5290/5335/71/5579/1495/1499/5567/207/5578/5568/3315/10152/6714/64223/5566/1432/3320/2534/4846/5603/208/79109/2475/23191/2185/60/808/3845/5600/3265/6300/801/5879/253260/805 39 Cucumber_mosaic_virus R-HSA-71387 Metabolism of carbohydrates 77/1181 295/10654 2.3118348931944613e-13 2.0515513842403995e-12 8.866146333119723e-13 5105/23165/4928/7167/5903/5313/132158/2597/55706/7175/9631/375790/5315/5567/2806/5568/5211/348995/79023/57122/23636/3099/5214/10762/6576/23511/5528/7316/229/53371/5230/2539/23279/4927/9688/79902/5566/26330/231/5519/5106/9883/2023/226/23225/2821/4190/669/5224/8086/5213/51071/6233/7086/7311/9972/6888/5518/6548/4191/8021/5236/808/129401/2026/230/801/5232/55746/2027/216/8480/7314/805/5515/5223/5516 77 Cucumber_mosaic_virus R-HSA-111996 Ca-dependent events 23/1181 38/10654 2.6158351927827487e-13 2.3052047636397974e-12 9.962354791226696e-13 818/815/3838/5567/817/5578/5594/5568/5582/114/108/107/10645/5566/84254/816/1385/808/115/801/814/109/805 23 Cucumber_mosaic_virus R-HSA-5673000 RAF activation 21/1181 32/10654 2.8585745884948884e-13 2.5017456226206988e-12 1.0811741274815512e-12 818/815/817/5528/6714/5605/5519/816/5894/5518/4140/808/3845/3265/369/801/5245/7529/805/5515/5516 21 Cucumber_mosaic_virus R-HSA-8851708 Signaling by FGFR2 IIIa TM 16/1181 19/10654 3.3190315481970545e-13 2.8848294757959328e-12 1.246730668068252e-12 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/5439/5432/22916 16 Cucumber_mosaic_virus R-HSA-1489509 DAG and IP3 signaling 24/1181 42/10654 4.672034165655492e-13 4.033205004229129e-12 1.743021697319378e-12 818/815/3838/5335/5567/817/5578/5568/5582/114/108/107/10645/5566/84254/816/1385/5581/808/115/801/814/109/805 24 Cucumber_mosaic_virus R-HSA-166520 Signaling by NTRKs 39/1181 101/10654 4.805215399073924e-13 4.120147527989736e-12 1.7805954643794554e-12 5295/9252/5290/3667/5335/1849/5594/1785/5528/6774/4205/6714/5605/5519/1432/4208/4914/2534/6195/5603/2885/1385/5906/5518/1213/8851/6197/3845/5600/3265/6300/1020/7529/5879/5595/5515/25920/5516/5607 39 Cucumber_mosaic_virus R-HSA-5578749 Transcriptional regulation by small RNAs 40/1181 106/10654 5.833133333121939e-13 4.937517644285072e-12 2.1338365830305854e-12 23165/27161/4928/5434/5440/5903/55706/7175/9631/5430/5436/348995/79023/57122/5441/23636/5438/10762/5431/23511/5435/5433/53371/23279/4927/9688/79902/9883/5437/23225/5439/5901/8086/9972/8021/129401/26523/5432/55746/8480 40 Cucumber_mosaic_virus R-HSA-187037 Signaling by NTRK1 (TRKA) 34/1181 80/10654 5.836309272204576e-13 4.937517644285072e-12 2.1338365830305854e-12 5295/9252/5290/3667/5335/1849/5594/1785/5528/6774/4205/6714/5605/5519/1432/4208/4914/6195/5603/2885/1385/5906/5518/1213/6197/3845/5600/3265/6300/7529/5595/5515/5516/5607 34 Cucumber_mosaic_virus R-HSA-111933 Calmodulin induced events 22/1181 36/10654 6.586408632761191e-13 5.498784575640757e-12 2.3763981285793494e-12 818/815/3838/5567/817/5578/5568/5582/114/108/107/10645/5566/84254/816/1385/808/115/801/814/109/805 22 Cucumber_mosaic_virus R-HSA-111997 CaM pathway 22/1181 36/10654 6.586408632761191e-13 5.498784575640757e-12 2.3763981285793494e-12 818/815/3838/5567/817/5578/5568/5582/114/108/107/10645/5566/84254/816/1385/808/115/801/814/109/805 22 Cucumber_mosaic_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 35/1181 85/10654 8.227160923363658e-13 6.7356562656441824e-12 2.9109343572648326e-12 8454/8945/5601/351/9252/5606/1849/5594/6500/51295/5528/7316/5970/4205/5519/1432/4208/5602/6195/10454/7189/6285/5609/6233/1385/7311/5518/1386/6197/5599/5600/7314/5595/5515/5516 35 Cucumber_mosaic_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 35/1181 85/10654 8.227160923363658e-13 6.7356562656441824e-12 2.9109343572648326e-12 8454/8945/5601/351/9252/5606/1849/5594/6500/51295/5528/7316/5970/4205/5519/1432/4208/5602/6195/10454/7189/6285/5609/6233/1385/7311/5518/1386/6197/5599/5600/7314/5595/5515/5516 35 Cucumber_mosaic_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 35/1181 85/10654 8.227160923363658e-13 6.7356562656441824e-12 2.9109343572648326e-12 8454/8945/5601/351/9252/5606/1849/5594/6500/51295/5528/7316/5970/4205/5519/1432/4208/5602/6195/10454/7189/6285/5609/6233/1385/7311/5518/1386/6197/5599/5600/7314/5595/5515/5516 35 Cucumber_mosaic_virus R-HSA-166166 MyD88-independent TLR4 cascade 38/1181 99/10654 1.1938455127242262e-12 9.649617551891994e-12 4.170254858393039e-12 8454/8945/5601/351/9252/5606/1849/5594/6500/841/5528/7316/5970/4205/7322/5519/1432/4208/329/5602/6195/10454/7189/6285/5609/6233/1385/7311/5518/1386/8772/6197/5599/5600/7314/5595/5515/5516 38 Cucumber_mosaic_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 38/1181 99/10654 1.1938455127242262e-12 9.649617551891994e-12 4.170254858393039e-12 8454/8945/5601/351/9252/5606/1849/5594/6500/841/5528/7316/5970/4205/7322/5519/1432/4208/329/5602/6195/10454/7189/6285/5609/6233/1385/7311/5518/1386/8772/6197/5599/5600/7314/5595/5515/5516 38 Cucumber_mosaic_virus R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 18/1181 25/10654 1.2724376214636535e-12 1.0219767985046684e-11 4.416655568171642e-12 10694/84617/10575/7277/10381/7278/112714/7203/10576/908/6950/7846/113457/10376/10574/10383/84790/22948 18 Cucumber_mosaic_virus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 20/1181 31/10654 1.7218030736380753e-12 1.37419377386586e-11 5.9388242394269265e-12 5601/9252/1849/5594/5528/4205/5519/1432/4208/5602/6195/1385/5518/1386/6197/5599/5600/5595/5515/5516 20 Cucumber_mosaic_virus R-HSA-4551638 SUMOylation of chromatin organization proteins 31/1181 71/10654 2.588873595223416e-12 2.053300370211572e-11 8.873704888890789e-12 23165/4928/5903/55706/7175/9631/348995/79023/6613/57122/23636/10762/23511/53371/9759/23279/4927/9688/79902/9883/23225/3066/3065/1107/8086/9972/6612/8021/129401/55746/8480 31 Cucumber_mosaic_virus R-HSA-111465 Apoptotic cleavage of cellular proteins 22/1181 38/10654 3.0973429338611956e-12 2.4413218528384208e-11 1.0550609143783477e-11 4000/2934/22985/51765/1499/63967/118/841/7082/5339/8428/10134/329/999/836/324/4137/4001/6709/839/840/7431 22 Cucumber_mosaic_virus R-HSA-72165 mRNA Splicing - Minor Pathway 26/1181 52/10654 3.196007957874598e-12 2.5035395670017685e-11 1.0819494126398088e-11 23451/2963/6635/5434/5440/6633/6432/5430/4904/5436/5441/5438/79622/5431/5435/10594/4686/5433/9343/2962/5437/5439/6427/5432/22916/10992 26 Cucumber_mosaic_virus R-HSA-111932 CaMK IV-mediated phosphorylation of CREB 12/1181 12/10654 3.274825626959008e-12 2.5495421598840376e-11 1.1018302561483004e-11 818/815/3838/817/10645/84254/816/1385/808/801/814/805 12 Cucumber_mosaic_virus R-HSA-68886 M Phase 91/1181 395/10654 3.736536965208532e-12 2.8912593956400168e-11 1.2495094729612614e-11 4000/23165/4926/84617/4928/26271/5684/5903/54908/55706/7175/55143/5579/9631/7531/1058/11190/203068/55125/5578/5594/5925/1460/7277/348995/79023/10381/57122/5705/23636/23310/7278/6232/112714/1780/10762/10051/5885/23511/5528/7316/10213/891/5501/53371/1457/983/1639/23279/4927/9688/79902/5566/5519/9883/5701/7846/23225/113457/3320/8815/22919/9126/10376/5710/8086/2010/4001/79648/5704/6233/7311/9972/5518/10383/84790/8021/9493/129401/1453/9793/10726/55746/7112/5693/10592/8480/7314/5595/5515/5516 91 Cucumber_mosaic_virus R-HSA-8878166 Transcriptional regulation by RUNX2 42/1181 121/10654 3.981626525475134e-12 3.0622327641381487e-11 1.323398672901145e-11 8454/25/1019/5684/10273/207/5594/6500/4086/5925/10013/3958/5705/7316/10213/9978/891/9759/983/1026/10413/6772/6714/2099/4089/2932/5701/6502/595/55294/5710/861/208/5704/6233/7525/7311/367/10432/5693/7314/5595 42 Cucumber_mosaic_virus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 31/1181 72/10654 4.070323258388689e-12 3.0821779771668285e-11 1.3320183535348327e-11 5563/84617/71/7531/4627/207/10971/51422/4644/7277/53632/10381/7278/7534/112714/4641/5571/7846/113457/10376/208/10383/60/84790/808/5564/801/5565/7529/5879/805 31 Cucumber_mosaic_virus R-HSA-448424 Interleukin-17 signaling 31/1181 72/10654 4.070323258388689e-12 3.0821779771668285e-11 1.3320183535348327e-11 8454/8945/5601/9252/5606/1849/5594/6500/5528/7316/4205/5519/1432/4208/5602/6195/10454/7189/5609/6233/1385/7311/5518/1386/6197/5599/5600/7314/5595/5515/5516 31 Cucumber_mosaic_virus R-HSA-194138 Signaling by VEGF 39/1181 107/10654 4.080424745185399e-12 3.0821779771668285e-11 1.3320183535348327e-11 5295/5170/5590/857/5290/5335/71/5579/1495/1499/5567/207/5578/5568/3315/10152/6714/64223/5566/1432/3320/2534/4846/5603/208/79109/2475/23191/2185/60/808/3845/5600/3265/6300/801/5879/253260/805 39 Cucumber_mosaic_virus R-HSA-5626467 RHO GTPases activate IQGAPs 20/1181 32/10654 4.115045764952406e-12 3.08993673119799e-11 1.3353714378948636e-11 84617/71/1495/1499/7277/10381/7278/112714/7846/999/113457/10376/8826/10383/60/84790/808/801/5879/805 20 Cucumber_mosaic_virus R-HSA-211000 Gene Silencing by RNA 45/1181 136/10654 4.578814995962141e-12 3.417950723456445e-11 1.4771285528769506e-11 23165/27161/4928/5434/5440/5903/55706/7175/9631/5430/5436/348995/79023/57122/5441/23636/192670/5438/10762/5431/23511/5435/5433/53371/23279/4927/9688/79902/9883/5437/23225/3320/5439/192669/5901/8086/9972/8575/8021/129401/26523/5432/55746/23405/8480 45 Cucumber_mosaic_virus R-HSA-5683057 MAPK family signaling cascades 74/1181 294/10654 4.8045323733936884e-12 3.565468761307948e-11 1.5408811120579327e-11 818/27161/815/5684/6711/3667/71/2309/10642/5567/817/1849/5594/5568/3315/5705/192670/2260/8452/5528/4684/7316/10213/9978/983/6714/5605/4609/5566/5519/5701/8649/2335/2534/1445/5710/2264/816/192669/5894/896/9693/5704/6233/2885/6709/7311/8826/5906/5518/1956/60/5536/4140/1843/808/3845/3265/26523/369/801/5693/4747/5245/7529/5156/7314/3572/5879/28956/5595/805/5515/5516 74 Cucumber_mosaic_virus R-HSA-68875 Mitotic Prophase 46/1181 142/10654 6.160418191969124e-12 4.545099235819081e-11 1.9642459473781603e-11 4000/23165/4926/4928/5903/55706/7175/5579/9631/5578/5594/5925/348995/79023/57122/23636/23310/10762/10051/23511/891/53371/983/23279/4927/9688/79902/5519/9883/23225/8815/8086/2010/4001/79648/9972/5518/8021/129401/55746/7112/10592/8480/5595/5515/5516 46 Cucumber_mosaic_virus R-HSA-6784531 tRNA processing in the nucleus 27/1181 57/10654 6.305307081115264e-12 4.625106754875878e-11 1.9988226280870412e-11 23165/4928/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/9972/8021/129401/55746/51493/8480 27 Cucumber_mosaic_virus R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission 58/1181 206/10654 8.198571017625812e-12 5.979302655958135e-11 2.5840626135408643e-11 818/5170/5563/84617/815/3838/8573/28964/5579/5567/817/4646/5578/5594/5568/51422/5582/7277/114/53632/10381/108/7278/112714/107/3359/10645/6714/5566/84254/5571/7846/113457/10376/6195/2783/4137/816/1385/5562/10383/84790/8874/808/6197/3845/115/3265/5564/801/5565/814/109/4747/5879/5595/4193/805 58 Cucumber_mosaic_virus R-HSA-3371571 HSF1-dependent transactivation 17/1181 24/10654 8.388599956924918e-12 6.082933340192983e-11 2.6288484677039894e-11 818/3303/815/817/84335/64223/1387/3320/2033/816/3326/2475/3306/3312/57521/2288/10728 17 Cucumber_mosaic_virus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 24/1181 47/10654 1.2282088886006365e-11 8.707246254939708e-11 3.7629922432280604e-011 818/815/71/817/5594/6714/5605/2335/1445/816/5894/8826/5906/60/4140/808/3845/3265/369/801/5245/7529/5595/805 24 Cucumber_mosaic_virus R-HSA-6802949 Signaling by RAS mutants 24/1181 47/10654 1.2282088886006365e-11 8.707246254939708e-11 3.7629922432280604e-011 818/815/71/817/5594/6714/5605/2335/1445/816/5894/8826/5906/60/4140/808/3845/3265/369/801/5245/7529/5595/805 24 Cucumber_mosaic_virus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 24/1181 47/10654 1.2282088886006365e-11 8.707246254939708e-11 3.7629922432280604e-011 818/815/71/817/5594/6714/5605/2335/1445/816/5894/8826/5906/60/4140/808/3845/3265/369/801/5245/7529/5595/805 24 Cucumber_mosaic_virus R-HSA-9649948 Signaling downstream of RAS mutants 24/1181 47/10654 1.2282088886006365e-11 8.707246254939708e-11 3.7629922432280604e-011 818/815/71/817/5594/6714/5605/2335/1445/816/5894/8826/5906/60/4140/808/3845/3265/369/801/5245/7529/5595/805 24 Cucumber_mosaic_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 35/1181 92/10654 1.255705863139468e-11 8.85272633513325e-11 3.825864062547735e-11 8454/8945/5601/351/9252/5606/1849/5594/6500/51295/5528/7316/5970/4205/5519/1432/4208/5602/6195/10454/7189/6285/5609/6233/1385/7311/5518/1386/6197/5599/5600/7314/5595/5515/5516 35 Cucumber_mosaic_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 36/1181 97/10654 1.490872547974284e-11 1.0452581565631858e-10 4.517270122097132e-11 8454/8945/5601/351/9252/5606/1849/5594/6500/51295/5528/7316/5970/4205/5289/5519/1432/4208/5602/6195/10454/7189/6285/5609/6233/1385/7311/5518/1386/6197/5599/5600/7314/5595/5515/5516 36 Cucumber_mosaic_virus R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 26/1181 55/10654 1.6484075844674343e-11 1.1493567168621836e-10 4.967150673843454e-11 3303/84617/830/7277/10381/7278/112714/1780/1639/832/2289/7846/113457/3320/10376/3301/10963/3326/3306/367/10383/84790/3312/2288/10728/829 26 Cucumber_mosaic_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 35/1181 93/10654 1.8024252565390045e-11 1.2430856796456504e-10 5.372217154787308e-11 8454/8945/5601/351/9252/5606/1849/5594/6500/51295/5528/7316/5970/4205/5519/1432/4208/5602/6195/10454/7189/6285/5609/6233/1385/7311/5518/1386/6197/5599/5600/7314/5595/5515/5516 35 Cucumber_mosaic_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 35/1181 93/10654 1.8024252565390045e-11 1.2430856796456504e-10 5.372217154787308e-11 8454/8945/5601/351/9252/5606/1849/5594/6500/51295/5528/7316/5970/4205/5519/1432/4208/5602/6195/10454/7189/6285/5609/6233/1385/7311/5518/1386/6197/5599/5600/7314/5595/5515/5516 35 Cucumber_mosaic_virus R-HSA-70263 Gluconeogenesis 20/1181 34/10654 2.0378503166478367e-11 1.3978551631492458e-10 6.041081166278936e-11 5105/7167/2597/2806/6576/229/5230/26330/5106/2023/226/2821/4190/5224/4191/2026/230/5232/2027/5223 20 Cucumber_mosaic_virus R-HSA-109581 Apoptosis 52/1181 178/10654 2.206012451555616e-11 1.5050697854968153e-10 6.504428337637102e-11 4000/2934/3837/5684/7186/22985/51765/1499/4976/7531/842/207/10971/5594/63967/118/5705/841/7534/7316/10213/7082/6774/5339/4836/8428/5701/10134/329/999/836/324/4137/5710/7157/4001/208/5704/6233/6709/7311/839/1677/840/1630/8772/5599/7431/5693/7529/7314/5595 52 Cucumber_mosaic_virus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 17/1181 25/10654 2.3510444919780173e-11 1.5954414226310715e-10 6.89498553515647e-11 5170/2309/842/207/84335/7249/6199/1026/64223/2932/208/79109/2475/1385/2931/253260/4193 17 Cucumber_mosaic_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 35/1181 95/10654 3.64368433815698e-11 2.446473769905401e-10 1.0572874075075393e-10 8454/8945/5601/351/9252/5606/1849/5594/6500/51295/5528/7316/5970/4205/5519/1432/4208/5602/6195/10454/7189/6285/5609/6233/1385/7311/5518/1386/6197/5599/5600/7314/5595/5515/5516 35 Cucumber_mosaic_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 35/1181 95/10654 3.64368433815698e-11 2.446473769905401e-10 1.0572874075075393e-10 8454/8945/5601/351/9252/5606/1849/5594/6500/51295/5528/7316/5970/4205/5519/1432/4208/5602/6195/10454/7189/6285/5609/6233/1385/7311/5518/1386/6197/5599/5600/7314/5595/5515/5516 35 Cucumber_mosaic_virus R-HSA-5357801 Programmed Cell Death 52/1181 181/10654 4.39901217995747e-11 2.93807708229791e-10 1.269742573827059e-10 4000/2934/3837/5684/7186/22985/51765/1499/4976/7531/842/207/10971/5594/63967/118/5705/841/7534/7316/10213/7082/6774/5339/4836/8428/5701/10134/329/999/836/324/4137/5710/7157/4001/208/5704/6233/6709/7311/839/1677/840/1630/8772/5599/7431/5693/7529/7314/5595 52 Cucumber_mosaic_virus R-HSA-8943724 Regulation of PTEN gene transcription 27/1181 61/10654 4.563710762921749e-11 3.0321198733757584e-10 1.3103848484333046e-10 5468/389541/5594/84232/58528/153129/1108/2122/64223/10014/10325/8649/6009/3066/3065/7157/1107/10542/2475/55004/1386/10670/8726/64121/57521/28956/5595 27 Cucumber_mosaic_virus R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 19/1181 32/10654 5.2080027314058266e-11 3.4421643052885384e-10 1.487592885450897e-10 10694/84617/10575/7277/10381/7278/112714/7203/10576/908/6950/7846/113457/10376/10574/10383/60/84790/22948 19 Cucumber_mosaic_virus R-HSA-69206 G1/S Transition 42/1181 131/10654 7.453640883159577e-11 4.900865430429794e-10 2.1179966730985217e-10 8454/1017/26271/1019/5684/902/8317/207/6500/54107/5925/5705/7316/10213/5422/4174/891/890/4331/983/1026/5111/4171/4609/5519/5701/6502/1874/595/5710/3065/208/5704/6233/7311/5518/1022/5693/7314/5515/6241/5516 42 Cucumber_mosaic_virus R-HSA-5655253 Signaling by FGFR2 in disease 22/1181 43/10654 8.461653672092548e-11 5.534968304064662e-10 2.392035574150959e-10 5295/2963/5434/5440/5290/5335/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/5439/2885/3845/3265/5432/22916 22 Cucumber_mosaic_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 35/1181 98/10654 1.0011927110623793e-10 6.482211991521221e-10 2.801403880040277e-10 8454/8945/5601/351/9252/5606/1849/5594/6500/51295/5528/7316/5970/4205/5519/1432/4208/5602/6195/10454/7189/6285/5609/6233/1385/7311/5518/1386/6197/5599/5600/7314/5595/5515/5516 35 Cucumber_mosaic_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 35/1181 98/10654 1.0011927110623793e-10 6.482211991521221e-10 2.801403880040277e-10 8454/8945/5601/351/9252/5606/1849/5594/6500/51295/5528/7316/5970/4205/5519/1432/4208/5602/6195/10454/7189/6285/5609/6233/1385/7311/5518/1386/6197/5599/5600/7314/5595/5515/5516 35 Cucumber_mosaic_virus R-HSA-1226099 Signaling by FGFR in disease 27/1181 63/10654 1.1347216770838406e-10 7.309450803144131e-10 3.158909931929901e-10 5295/2963/5434/5440/5290/5335/5430/5436/5441/2260/5438/5431/5435/4686/5433/6774/6772/2962/399687/5437/5439/2264/2885/3845/3265/5432/22916 27 Cucumber_mosaic_virus R-HSA-5675221 Negative regulation of MAPK pathway 21/1181 40/10654 1.2095052750110662e-10 7.751829262570924e-10 3.350091697399072e-10 1849/5594/5528/7316/5605/5519/5894/6233/7311/5518/5536/4140/1843/3845/3265/369/7529/7314/5595/5515/5516 21 Cucumber_mosaic_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 41/1181 129/10654 1.7009130382065203e-10 1.0846525856703892e-9 4.687520195216066e-10 8454/8945/5601/351/9252/5606/5336/1849/5594/1785/6500/51295/841/5528/7316/5970/4205/7322/5519/1432/4208/329/5602/6195/10454/7189/6285/5609/6233/1385/7311/5518/1386/8772/6197/5599/5600/7314/5595/5515/5516 41 Cucumber_mosaic_virus R-HSA-75153 Apoptotic execution phase 24/1181 52/10654 1.8737489636514596e-10 1.188893717436851e-9 5.138016895065319e-10 4000/2934/3837/22985/51765/1499/63967/118/841/7082/5339/8428/10134/329/999/836/324/4137/4001/6709/839/1677/840/7431 24 Cucumber_mosaic_virus R-HSA-9018519 Estrogen-dependent gene expression 45/1181 150/10654 1.893031658786732e-10 1.1951528233832652e-9 5.165066741177729e-10 27161/2963/3838/5434/5440/5430/5436/5451/5441/192670/5438/5431/5885/5435/5433/1509/5469/1655/6667/2099/4609/2962/2958/1387/5437/3320/2033/9126/595/4602/5439/192669/3065/861/3326/1025/1386/6908/904/26523/23189/5432/2288/10728/2957 45 Cucumber_mosaic_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 29/1181 73/10654 2.1356185894961845e-10 1.3416336584508208e-9 5.798109875599335e-10 5590/892/10273/51592/7316/5501/6667/4609/4089/22938/8812/4088/1874/142/905/5494/3065/2280/9958/9040/4087/5499/6233/1025/7311/7040/904/5500/7314 29 Cucumber_mosaic_virus R-HSA-442729 CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde 10/1181 10/10654 2.707786081064328e-10 1.6926997718574543e-9 7.315304891026782e-10 818/3838/10645/84254/816/1385/808/801/814/805 10 Cucumber_mosaic_virus R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 17/1181 28/10654 3.3680236603052214e-10 2.095108835748689e-9 9.054387652316927e-10 10694/84617/10575/7277/10381/7278/7203/10576/908/6950/7846/113457/10574/10383/60/84790/22948 17 Cucumber_mosaic_virus R-HSA-69275 G2/M Transition 53/1181 196/10654 3.3902017622015596e-10 2.098617578650624e-9 9.069551312487869e-10 8454/1017/8945/84617/5684/4605/902/7531/4659/11190/203068/55125/6500/7277/10381/5705/7278/112714/7316/10213/9978/891/890/4331/983/1026/1639/5566/5519/5701/7846/113457/3320/22919/2033/10376/5710/7157/5704/6233/3326/7311/5518/10383/84790/1453/9793/1022/5693/5500/7314/5515/5516 53 Cucumber_mosaic_virus R-HSA-198753 ERK/MAPK targets 15/1181 22/10654 3.4609638581442275e-10 2.1320209397985554e-9 9.213909913608292e-10 9252/1849/5594/5528/4205/5519/1432/4208/6195/5518/6197/5600/5595/5515/5516 15 Cucumber_mosaic_virus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 16/1181 25/10654 3.6477954976819335e-10 2.236257239883272e-9 9.664385732480486e-10 9252/1849/5594/5528/4205/5519/1432/4208/6195/1385/5518/6197/5600/5595/5515/5516 16 Cucumber_mosaic_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 32/1181 88/10654 3.728466777915808e-10 2.2747232409495965e-9 9.83062343772336e-10 3303/5684/5073/207/5578/3184/3315/26986/5705/7534/7316/10213/1432/5701/1981/5710/5704/6233/7311/8021/51010/54464/5600/56915/3312/8570/5693/54512/167227/7529/7314/1994 32 Cucumber_mosaic_virus R-HSA-449147 Signaling by Interleukins 96/1181 461/10654 3.915537648668922e-10 2.3774245340482595e-9 1.0274465449289893e-9 5295/8454/7124/834/8945/5684/5601/351/1072/9252/5290/3667/5606/2309/9049/7412/207/5451/1849/5594/8878/6500/3091/5705/301/4478/7534/3313/5528/7316/10213/6175/9978/6774/920/5970/4205/6850/1026/5780/6772/4609/6647/5566/5519/1432/4208/5701/6950/4088/836/3320/5602/4843/2335/2534/595/6195/5710/3181/10454/7157/9244/5478/4001/7189/6285/5609/5704/6233/2885/7525/1385/7311/53832/3932/6888/5518/2185/302/1386/7040/6197/5599/5600/7431/4282/3312/5693/5034/829/7314/3572/5595/5515/5516 96 Cucumber_mosaic_virus R-HSA-453274 Mitotic G2-G2/M phases 53/1181 198/10654 5.073556699145812e-10 3.065877833912398e-9 1.3249739550150218e-9 8454/1017/8945/84617/5684/4605/902/7531/4659/11190/203068/55125/6500/7277/10381/5705/7278/112714/7316/10213/9978/891/890/4331/983/1026/1639/5566/5519/5701/7846/113457/3320/22919/2033/10376/5710/7157/5704/6233/3326/7311/5518/10383/84790/1453/9793/1022/5693/5500/7314/5515/5516 53 Cucumber_mosaic_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 41/1181 134/10654 6.278364452964417e-10 3.7759452563089315e-9 1.6318422948338546e-9 5295/8454/5170/8945/5684/5601/5290/5335/5336/5594/4775/6500/5705/7316/10213/5970/6850/8915/7322/5701/5602/2534/5710/10454/7189/5609/5704/6233/2885/7311/808/3845/5599/3265/801/5693/997/7314/5879/5595/805 41 Cucumber_mosaic_virus R-HSA-437239 Recycling pathway of L1 22/1181 47/10654 7.692829106955526e-10 4.6048113852483786e-9 1.9900516210148108e-9 84617/9252/71/7430/5594/1785/7277/10381/4478/7278/112714/6714/7846/113457/10376/6195/5962/1213/10383/60/84790/6197 22 Cucumber_mosaic_virus R-HSA-9022692 Regulation of MECP2 expression and activity 18/1181 33/10654 1.147398404562921e-9 6.835908804649515e-9 2.9542602855314156e-9 818/27161/815/817/3930/192670/5566/3064/816/192669/3066/3065/1385/808/26523/801/814/805 18 Cucumber_mosaic_virus R-HSA-9607240 FLT3 Signaling 64/1181 267/10654 1.210575361144094e-9 7.178598753700258e-9 3.1023598777967187e-9 5295/818/5170/815/5684/6711/5290/3667/71/817/1849/5594/5705/2260/8452/5528/4684/7316/10213/9978/5289/6714/5605/5519/5701/8649/2335/2534/1445/5710/2264/816/5894/9693/208/5704/6233/2885/6709/7311/8826/5906/5518/1956/60/5536/4140/1843/808/3845/3265/369/801/5693/4747/5245/7529/5156/7314/28956/5595/805/5515/5516 64 Cucumber_mosaic_virus R-HSA-112315 Transmission across Chemical Synapses 64/1181 272/10654 2.690345942632298e-9 1.5879297680001797e-8 6.862522575820942e-9 818/5170/5563/84617/815/3838/8573/28964/1312/5579/5567/817/4646/5578/5594/5568/51422/5582/7277/114/53632/10381/108/7278/112714/107/3359/10645/6714/5566/84254/5571/7846/590/113457/10376/6195/2783/4137/18/816/1385/5562/10383/84790/8874/808/6197/3845/115/3265/3312/5564/801/5565/814/109/6506/4747/6812/5879/5595/4193/805 64 Cucumber_mosaic_virus R-HSA-112043 PLC beta mediated events 23/1181 54/10654 3.164239184399746e-9 1.8589905208348508e-8 8.03396011243795e-9 818/815/3838/5567/817/5578/5594/5568/5582/114/108/107/10645/5566/84254/816/1385/808/115/801/814/109/805 23 Cucumber_mosaic_virus R-HSA-5684996 MAPK1/MAPK3 signaling 61/1181 255/10654 3.240816761221013e-9 1.895205746538924e-8 8.190470689285219e-9 818/815/5684/6711/3667/71/817/1849/5594/5705/2260/8452/5528/4684/7316/10213/9978/983/6714/5605/5519/5701/8649/2335/2534/1445/5710/2264/816/5894/9693/5704/6233/2885/6709/7311/8826/5906/5518/1956/60/5536/4140/1843/808/3845/3265/369/801/5693/4747/5245/7529/5156/7314/3572/28956/5595/805/5515/5516 61 Cucumber_mosaic_virus R-HSA-1227986 Signaling by ERBB2 22/1181 50/10654 3.312503491981944e-9 1.9282417116170123e-8 8.333241522562013e-9 5295/8065/5290/5335/10273/207/5578/7316/6714/3320/2534/208/6233/2885/7525/7311/1956/5581/3845/3265/11140/7314 22 Cucumber_mosaic_virus R-HSA-1295596 Spry regulation of FGF signaling 12/1181 16/10654 3.887792972943884e-9 2.2527896267880312e-8 9.735833400162286e-9 5594/7316/6714/8569/6233/2885/7311/5518/7314/5595/5515/5516 12 Cucumber_mosaic_virus R-HSA-111885 Opioid Signalling 31/1181 91/10654 4.425560089864506e-9 2.5527435245627538e-8 1.1032137831671808e-8 818/815/3838/5567/817/5578/5594/5568/5582/114/108/5528/107/10645/5566/84254/5519/2783/816/5499/1385/5518/808/115/801/1020/814/109/805/5515/5516 31 Cucumber_mosaic_virus R-HSA-8878159 Transcriptional regulation by RUNX3 32/1181 96/10654 4.614146058699437e-9 2.649480248185333e-8 1.1450202889175551e-8 5684/2309/1499/5705/7316/10213/9759/1026/10413/6714/4609/4089/22938/5701/1387/4088/2033/595/5710/7157/861/5704/6233/7311/7040/3845/3516/4851/5693/3676/7314/4193 32 Cucumber_mosaic_virus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 28/1181 77/10654 4.68369052037948e-9 2.677298770433135e-8 1.1570425609851632e-8 84617/5684/7277/10381/5705/7278/112714/7316/10213/891/983/1026/5701/7846/113457/3320/22919/10376/5710/7157/5704/6233/3326/7311/10383/84790/5693/7314 28 Cucumber_mosaic_virus R-HSA-2219528 PI3K/AKT Signaling in Cancer 33/1181 101/10654 4.713081014757176e-9 2.68201785099859e-8 1.1590819960766999e-8 5295/5170/5290/3667/6801/2309/842/207/84335/7249/6199/2260/2100/1026/6714/2099/64223/2932/2534/5728/2264/208/2885/79109/2475/1385/3932/2931/1956/5156/5879/253260/4193 33 Cucumber_mosaic_virus R-HSA-112040 G-protein mediated events 23/1181 55/10654 4.873348176995337e-9 2.7608387663424476e-8 1.1931458647624863e-8 818/815/3838/5567/817/5578/5594/5568/5582/114/108/107/10645/5566/84254/816/1385/808/115/801/814/109/805 23 Cucumber_mosaic_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 13/1181 19/10654 5.12523855678081e-9 2.8778441276791365e-8 1.2437118249104808e-8 5295/5290/5335/7316/3320/6233/2885/7311/1956/3845/3265/11140/7314 13 Cucumber_mosaic_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 13/1181 19/10654 5.12523855678081e-9 2.8778441276791365e-8 1.2437118249104808e-8 5295/5290/5335/7316/3320/6233/2885/7311/1956/3845/3265/11140/7314 13 Cucumber_mosaic_virus R-HSA-5696395 Formation of Incision Complex in GG-NER 20/1181 43/10654 5.254817460508855e-9 2.9376050032536286e-8 1.2695385564224966e-8 902/404672/6613/8450/7316/9978/4331/2966/2965/142/2068/2071/6233/2968/7311/2967/6612/1022/7314/8451 20 Cucumber_mosaic_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 21/1181 47/10654 5.372625804639139e-9 2.9772323782039597e-8 1.2866642354479391e-8 8454/892/6500/3091/10013/7316/9978/9759/4609/10014/22938/1387/2033/55294/3066/3065/6233/7311/3516/4851/7314 21 Cucumber_mosaic_virus R-HSA-73762 RNA Polymerase I Transcription Initiation 21/1181 47/10654 5.372625804639139e-9 2.9772323782039597e-8 1.2866642354479391e-8 5434/5440/902/25885/404672/5441/5435/4331/1108/2966/5437/2965/2068/3066/3065/2071/1107/2968/2967/6908/1022 21 Cucumber_mosaic_virus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 17/1181 32/10654 5.744962287880258e-9 3.155998763342012e-8 1.3639213269471927e-8 892/7316/6667/4609/4089/22938/8812/4088/1874/905/3065/4087/6233/1025/7311/904/7314 17 Cucumber_mosaic_virus R-HSA-73863 RNA Polymerase I Transcription Termination 17/1181 32/10654 5.744962287880258e-9 3.155998763342012e-8 1.3639213269471927e-8 5434/5440/902/25885/404672/5441/5435/4331/2966/5437/2965/2068/2071/2968/2967/6908/1022 17 Cucumber_mosaic_virus R-HSA-168898 Toll-like Receptor Cascades 43/1181 155/10654 6.8762983026412595e-9 3.761216614677482e-8 1.6254770488548532e-8 8454/8945/5601/351/9252/5606/5336/1849/5594/1785/6500/51295/841/5528/7316/5970/4205/5289/5641/7322/5519/1432/4208/329/5602/6195/10454/7189/6285/5609/6233/1385/7311/5518/1386/8772/6197/5599/5600/7314/5595/5515/5516 43 Cucumber_mosaic_virus R-HSA-5218920 VEGFR2 mediated vascular permeability 16/1181 29/10654 7.854874242193981e-9 4.278040949933117e-8 1.8488319314131756e-8 5170/857/1495/1499/207/64223/3320/4846/208/79109/2475/808/801/5879/253260/805 16 Cucumber_mosaic_virus R-HSA-5673001 RAF/MAP kinase cascade 59/1181 249/10654 8.597850014625689e-9 4.662680200239316e-8 2.015060664696349e-8 818/815/5684/6711/3667/71/817/1849/5594/5705/2260/8452/5528/4684/7316/10213/9978/6714/5605/5519/5701/8649/2335/2534/1445/5710/2264/816/5894/9693/5704/6233/2885/6709/7311/8826/5906/5518/1956/60/5536/4140/1843/808/3845/3265/369/801/5693/4747/5245/7529/5156/7314/28956/5595/805/5515/5516 59 Cucumber_mosaic_virus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 20/1181 44/10654 8.636871043913014e-9 4.6639103637130276e-8 2.015592301849353e-8 892/51592/7316/6667/4609/4089/22938/8812/4088/1874/142/905/5494/3065/4087/6233/1025/7311/904/7314 20 Cucumber_mosaic_virus R-HSA-2555396 Mitotic Metaphase and Anaphase 51/1181 202/10654 9.464439212136924e-9 5.089141254322778e-8 2.1993634386812386e-8 4000/84617/4928/26271/5684/5903/54908/55143/1058/7277/348995/79023/10381/57122/5705/7278/6232/112714/1780/5885/5528/7316/10213/5501/23279/79902/5519/5701/7846/113457/8815/22919/9126/10376/5710/2010/4001/5704/6233/7311/5518/10383/84790/9793/10726/55746/7112/5693/7314/5515/5516 51 Cucumber_mosaic_virus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 21/1181 49/10654 1.3430110400831095e-8 7.191059113356397e-8 3.107744845140129e-8 1017/4849/4869/4850/9337/891/890/983/1026/5111/25904/246175/4848/23019/2033/1874/7157/55571/57472/85456/29883 21 Cucumber_mosaic_virus R-HSA-5696400 Dual Incision in GG-NER 19/1181 41/10654 1.3735529793516822e-8 7.323692146207078e-8 3.1650645831146685e-8 404672/54107/8450/7316/9978/5111/2966/2965/142/2068/2071/5984/6233/2968/7311/2967/5983/7314/8451 19 Cucumber_mosaic_virus R-HSA-5621481 C-type lectin receptors (CLRs) 40/1181 142/10654 1.4382423004284553e-8 7.636525017756108e-8 3.3002609051892764e-8 8454/5170/8945/5684/9252/5567/5336/5568/4775/6500/5705/841/7316/10213/5970/6850/8915/6714/5566/7322/5701/1387/2534/2033/5710/10454/9040/5894/7189/5704/6233/7311/808/3845/3265/801/5693/997/7314/805 40 Cucumber_mosaic_virus R-HSA-264870 Caspase-mediated cleavage of cytoskeletal proteins 10/1181 12/10654 1.4476737478074102e-8 7.654574941531682e-8 3.308061502665179e-8 2934/118/841/5339/836/4137/6709/839/840/7431 10 Cucumber_mosaic_virus R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 16/1181 30/10654 1.5104675292421983e-8 7.953457653976554e-8 3.437229013912144e-8 818/5170/815/817/5594/6195/816/1385/808/6197/3845/3265/801/4747/5595/805 16 Cucumber_mosaic_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 23/1181 58/10654 1.6532908715809422e-8 8.52856144730169e-8 3.685770406904882e-8 8454/892/6500/10013/7316/9978/3714/9759/4609/5664/10014/22938/1387/2033/55294/3066/3065/6233/7311/3516/4851/5663/7314 23 Cucumber_mosaic_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 23/1181 58/10654 1.6532908715809422e-8 8.52856144730169e-8 3.685770406904882e-8 8454/892/6500/10013/7316/9978/3714/9759/4609/5664/10014/22938/1387/2033/55294/3066/3065/6233/7311/3516/4851/5663/7314 23 Cucumber_mosaic_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 23/1181 58/10654 1.6532908715809422e-8 8.52856144730169e-8 3.685770406904882e-8 8454/892/6500/10013/7316/9978/3714/9759/4609/5664/10014/22938/1387/2033/55294/3066/3065/6233/7311/3516/4851/5663/7314 23 Cucumber_mosaic_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 23/1181 58/10654 1.6532908715809422e-8 8.52856144730169e-8 3.685770406904882e-8 8454/892/6500/10013/7316/9978/3714/9759/4609/5664/10014/22938/1387/2033/55294/3066/3065/6233/7311/3516/4851/5663/7314 23 Cucumber_mosaic_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 23/1181 58/10654 1.6532908715809422e-8 8.52856144730169e-8 3.685770406904882e-8 8454/892/6500/10013/7316/9978/3714/9759/4609/5664/10014/22938/1387/2033/55294/3066/3065/6233/7311/3516/4851/5663/7314 23 Cucumber_mosaic_virus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 29/1181 86/10654 1.8093267836884544e-8 9.29569104656133e-8 4.017299187307414e-8 5295/25/1072/5290/5335/71/10093/5336/4627/5594/2268/4644/6850/10094/10152/4641/6714/5337/3320/2534/2885/7525/10096/3326/23191/60/5581/5879/5595 29 Cucumber_mosaic_virus R-HSA-391251 Protein folding 32/1181 101/10654 1.8720352992265535e-8 9.579083849671358e-8 4.139772457118143e-8 10694/84617/22803/10575/10528/1460/7277/10381/7278/112714/7203/10576/908/6774/1457/6902/26330/1155/26270/6950/7846/113457/10376/55294/2783/7157/10574/10383/60/84790/22948/6499 32 Cucumber_mosaic_virus R-HSA-9009391 Extra-nuclear estrogen signaling 27/1181 77/10654 2.1734918977081105e-8 1.1076952683500371e-7 4.787103270792329e-8 5295/5170/5590/857/5290/6801/2309/207/5594/6722/3315/2100/6714/2099/3320/4846/595/2783/208/1385/1956/808/3845/3265/801/5595/805 27 Cucumber_mosaic_virus R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 9/1181 10/10654 2.2157175831589747e-8 1.120217375708661e-7 4.841219797969494e-8 5563/51422/53632/1432/5571/5600/5564/6300/5565 9 Cucumber_mosaic_virus R-HSA-390450 Folding of actin by CCT/TriC 9/1181 10/10654 2.2157175831589747e-8 1.120217375708661e-7 4.841219797969494e-8 10694/10575/7203/10576/908/6950/10574/60/22948 9 Cucumber_mosaic_virus R-HSA-68882 Mitotic Anaphase 50/1181 201/10654 2.2321126545539923e-8 1.1240281581861176e-7 4.857688776201462e-8 4000/84617/4928/5684/5903/54908/55143/1058/7277/348995/79023/10381/57122/5705/7278/6232/112714/1780/5885/5528/7316/10213/5501/23279/79902/5519/5701/7846/113457/8815/22919/9126/10376/5710/2010/4001/5704/6233/7311/5518/10383/84790/9793/10726/55746/7112/5693/7314/5515/5516 50 Cucumber_mosaic_virus R-HSA-5627123 RHO GTPases activate PAKs 14/1181 24/10654 2.6359373864905913e-8 1.3221361831844112e-7 5.713848048103175e-8 4659/4627/2316/10627/2017/4637/79784/4628/103910/808/801/5500/5879/805 14 Cucumber_mosaic_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 22/1181 55/10654 2.807682531115535e-8 1.4027358787344938e-7 6.062174051849124e-8 834/351/842/835/7295/841/7316/5970/22861/1432/329/837/5603/10454/7189/6233/3326/7311/5600/1540/6300/7314 22 Cucumber_mosaic_virus R-HSA-5610787 Hedgehog 'off' state 34/1181 113/10654 2.9062500403766673e-8 1.446286784799212e-7 6.250387083740944e-8 8454/8945/84617/5684/5567/1452/5568/6500/7277/114/10381/5705/108/7278/7316/10213/9978/107/5566/2932/5701/7846/113457/10376/5710/5704/6233/7311/10383/84790/115/5693/109/7314 34 Cucumber_mosaic_virus R-HSA-5663220 RHO GTPases Activate Formins 39/1181 140/10654 3.0464348269090707e-8 1.5101272638076605e-7 6.52628513494912e-8 84617/4928/5903/54908/71/55143/1058/6722/7277/348995/79023/10381/57122/7278/6232/112714/1780/5528/5501/5216/81624/6714/23279/79902/5519/7846/113457/22919/10376/5518/10383/60/84790/9793/10726/55746/5879/5515/5516 39 Cucumber_mosaic_virus R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 13/1181 21/10654 3.102652273615592e-8 1.5320100137035745e-7 6.620855353486478e-8 4849/4869/4850/9337/25904/246175/4848/23019/7157/55571/57472/85456/29883 13 Cucumber_mosaic_virus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 28/1181 84/10654 4.230211582008797e-8 2.0806738362671176e-7 8.992004219610702e-8 902/404672/54107/6613/86/8450/7316/9978/4331/5111/2966/2965/142/2068/10987/2071/5984/6233/2968/7311/2967/6612/60/8607/5983/1022/7314/8451 28 Cucumber_mosaic_virus R-HSA-2500257 Resolution of Sister Chromatid Cohesion 36/1181 126/10654 5.0718541690329657e-8 2.485012718340862e-7 1.0739427035424404e-7 84617/4928/5903/54908/55143/1058/7277/348995/79023/10381/57122/7278/6232/112714/1780/5885/5528/891/5501/983/23279/79902/5519/7846/113457/22919/9126/10376/5518/10383/84790/9793/10726/55746/5515/5516 36 Cucumber_mosaic_virus R-HSA-68877 Mitotic Prometaphase 49/1181 200/10654 5.185344566901819e-8 2.5308470213070803e-7 1.0937508175529747e-7 4926/84617/4928/5903/54908/55143/7531/1058/11190/203068/55125/1460/7277/348995/79023/10381/57122/7278/6232/112714/1780/10051/5885/5528/891/5501/1457/983/1639/23279/79902/5566/5519/7846/113457/3320/22919/9126/10376/5518/10383/84790/1453/9793/10726/55746/10592/5515/5516 49 Cucumber_mosaic_virus R-HSA-390466 Chaperonin-mediated protein folding 30/1181 95/10654 5.6452089155444906e-8 2.739715403568867e-7 1.1840170256392351e-7 10694/84617/22803/10575/10528/1460/7277/10381/7278/112714/7203/10576/908/6774/1457/26330/26270/6950/7846/113457/10376/55294/2783/7157/10574/10383/60/84790/22948/6499 30 Cucumber_mosaic_virus R-HSA-168638 NOD1/2 Signaling Pathway 17/1181 36/10654 5.6564652146181494e-8 2.739715403568867e-7 1.1840170256392351e-7 834/842/835/841/7316/1432/329/837/5603/10454/7189/6233/7311/5600/1540/6300/7314 17 Cucumber_mosaic_virus R-HSA-5674135 MAP2K and MAPK activation 18/1181 40/10654 5.856314432374426e-8 2.8257273820088006e-7 1.2211886408913653e-7 71/5594/6714/5605/8649/2335/1445/5894/8826/5906/60/4140/3845/3265/369/7529/28956/5595 18 Cucumber_mosaic_virus R-HSA-6802957 Oncogenic MAPK signaling 25/1181 71/10654 6.561055412429233e-8 3.153780044838143e-7 1.3629624680524843e-7 4000/818/815/71/817/5594/6714/5605/2335/1445/816/5894/8826/5906/60/4140/808/3845/3265/369/801/5245/7529/5595/805 25 Cucumber_mosaic_virus R-HSA-9613829 Chaperone Mediated Autophagy 13/1181 22/10654 6.814481073751618e-8 3.263236408524832e-7 1.4102659938131452e-7 1915/1080/10013/7316/3920/3320/6233/3326/7311/7431/3312/11315/7314 13 Cucumber_mosaic_virus R-HSA-8986944 Transcriptional Regulation by MECP2 23/1181 62/10654 7.232896946042585e-8 3.450581287416557e-7 1.4912304348587996e-7 818/27161/815/5468/6446/817/3930/192670/2289/5566/4208/3064/5728/816/192669/3066/3065/1385/808/26523/801/814/805 23 Cucumber_mosaic_virus R-HSA-6802952 Signaling by BRAF and RAF fusions 24/1181 67/10654 8.232062450816654e-8 3.9125420412308364e-7 1.6908750391781892e-7 4000/818/815/71/817/5594/6714/5605/2335/1445/816/5894/8826/5906/60/4140/808/3845/3265/369/801/7529/5595/805 24 Cucumber_mosaic_virus R-HSA-194315 Signaling by Rho GTPases 88/1181 455/10654 8.567299625792238e-8 4.0566803078844586e-007 1.7531669697713103e-7 9181/5170/84617/4928/25/5590/5903/1072/54908/71/55143/5579/1495/1499/7531/1058/4659/10093/4627/2316/10971/5578/5594/6722/10627/1080/7277/348995/79023/54509/10381/57122/7278/6232/7534/112714/1780/5528/5501/5289/5585/5216/81624/10094/10152/6714/23279/79902/5519/1432/2017/4637/7846/999/113457/89953/22919/79784/10376/11113/4628/2/2885/10096/23191/367/8826/5518/3799/10383/103910/60/5300/84790/8874/808/5600/801/9793/10726/55746/5500/7529/5879/5595/805/5515/5516 88 Cucumber_mosaic_virus R-HSA-1839126 FGFR2 mutant receptor activation 16/1181 33/10654 8.760478455068437e-8 4.1327312860527313e-7 1.7860337605520076e-7 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/5439/5432/22916 16 Cucumber_mosaic_virus R-HSA-9006936 Signaling by TGF-beta family members 31/1181 102/10654 9.145392492392801e-8 4.2983344714246167e-7 1.85760213978037e-7 5590/892/10273/4086/51592/7316/5501/6667/4609/4089/22938/8812/4088/1874/142/905/5494/3065/2280/9958/9040/4087/5499/657/6233/1025/7311/7040/904/5500/7314 31 Cucumber_mosaic_virus R-HSA-5654743 Signaling by FGFR4 18/1181 41/10654 9.36456252604443e-8 4.3851032640407314e-7 1.8951008258182745e-7 5295/5290/5335/5594/7316/6714/8569/2264/6233/2885/7311/5518/3845/3265/7314/5595/5515/5516 18 Cucumber_mosaic_virus R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 22/1181 59/10654 1.248922729963108e-7 5.82677553059994e-7 2.518145287580415e-7 7319/9646/79577/220441/5591/7316/56254/8915/5111/7415/7322/9810/54623/6233/23168/7311/10670/3105/6596/80349/7314/123169 22 Cucumber_mosaic_virus R-HSA-69202 Cyclin E associated events during G1/S transition 27/1181 83/10654 1.3057587367665106e-7 6.069625776398176e-7 2.6230973659354237e-7 8454/1017/1019/5684/902/207/6500/5925/5705/7316/10213/890/4331/1026/4609/5701/6502/1874/595/5710/208/5704/6233/7311/1022/5693/7314 27 Cucumber_mosaic_virus R-HSA-8852135 Protein ubiquitination 26/1181 79/10654 1.7118792533355163e-7 7.928375082053905e-7 3.4263891317241793e-7 7319/9646/79577/220441/5591/7316/56254/8915/5111/7415/7322/9810/54623/7347/6233/23168/7311/10670/55284/27338/3105/997/6596/80349/7314/123169 26 Cucumber_mosaic_virus R-HSA-8934593 Regulation of RUNX1 Expression and Activity 11/1181 17/10654 1.951600450235887e-7 9.005748986724874e-7 3.891995539035013e-7 27161/894/192670/6714/1021/595/192669/861/896/5371/26523 11 Cucumber_mosaic_virus R-HSA-388841 Costimulation by the CD28 family 24/1181 70/10654 2.1363956393026463e-7 9.822775602445863e-7 4.2450882077676536e-7 5295/5170/5290/207/3123/5528/3122/920/6714/64223/5519/2534/1445/208/2885/7525/79109/2475/3932/5518/5879/253260/5515/5516 24 Cucumber_mosaic_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 27/1181 85/10654 2.2633625963791532e-7 1.0368978826011356e-6 4.481139702502523e-7 8454/1017/1019/5684/902/207/6500/5925/5705/7316/10213/890/4331/1026/4609/5701/6502/1874/595/5710/208/5704/6233/7311/1022/5693/7314 27 Cucumber_mosaic_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 30/1181 101/10654 2.5785611814072934e-7 1.1770482515128974e-6 5.086824594900416e-7 8454/5170/8945/5684/5336/4775/6500/5705/841/7316/10213/5970/6850/8915/6714/7322/5701/5710/10454/9040/7189/5704/6233/7311/808/801/5693/997/7314/805 30 Cucumber_mosaic_virus R-HSA-111931 PKA-mediated phosphorylation of CREB 12/1181 21/10654 3.6864735791020594e-7 1.6767508859786788e-6 7.246378927418121e-7 5567/5568/114/108/107/5566/1385/808/115/801/109/805 12 Cucumber_mosaic_virus R-HSA-5654741 Signaling by FGFR3 17/1181 40/10654 3.784647359578789e-7 1.7152562497519585e-6 7.412786745641161e-7 5295/5290/5335/5594/7316/6714/8569/6233/2885/7311/5518/3845/3265/7314/5595/5515/5516 17 Cucumber_mosaic_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 15/1181 32/10654 3.9027114142219857e-7 1.7589026493113788e-6 7.60141246975429e-7 10273/7316/5501/4089/4088/2280/9958/9040/4087/5499/6233/7311/7040/5500/7314 15 Cucumber_mosaic_virus R-HSA-373760 L1CAM interactions 33/1181 119/10654 3.9086725540252864e-7 1.7589026493113788e-6 7.60141246975429e-7 84617/9252/6711/71/7430/5594/1785/1460/7277/10381/4478/2260/7278/112714/4684/1457/6714/5605/7846/113457/10376/6195/6709/5962/1213/10383/1956/60/84790/6197/3312/5879/5595 33 Cucumber_mosaic_virus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 16/1181 36/10654 3.9677976533114735e-7 1.7791997251068056e-6 7.689129913986527e-7 71/5594/6714/5605/2335/1445/5894/8826/5906/60/4140/3845/3265/369/7529/5595 16 Cucumber_mosaic_virus R-HSA-2467813 Separation of Sister Chromatids 45/1181 190/10654 5.119332252757689e-7 2.2874762777287e-6 9.885737967704804e-7 84617/4928/5684/5903/54908/55143/1058/7277/348995/79023/10381/57122/5705/7278/6232/112714/1780/5885/5528/7316/10213/5501/23279/79902/5519/5701/7846/113457/22919/9126/10376/5710/5704/6233/7311/5518/10383/84790/9793/10726/55746/5693/7314/5515/5516 45 Cucumber_mosaic_virus R-HSA-1643713 Signaling by EGFR in Cancer 13/1181 25/10654 5.16968670321229e-7 2.3018710267987356e-6 9.947947451056706e-7 5295/5290/5335/7316/3320/6233/2885/7311/1956/3845/3265/11140/7314 13 Cucumber_mosaic_virus R-HSA-1980143 Signaling by NOTCH1 24/1181 73/10654 5.191447910399568e-7 2.3034781112926752e-6 9.954892754207488e-7 8454/892/6500/3091/10013/7316/9978/3714/9759/4609/5664/10014/22938/1387/2033/55294/3066/3065/6233/7311/3516/4851/5663/7314 24 Cucumber_mosaic_virus R-HSA-5358351 Signaling by Hedgehog 38/1181 149/10654 5.533200561302708e-7 2.4465615025411625e-6 1.0573253227356358e-6 8454/8945/84617/5684/5567/1452/5568/6500/79577/7277/114/10381/5705/108/7278/8452/7316/10213/9978/107/7415/5566/2932/5701/7846/113457/10376/5710/5704/6233/7311/10383/84790/115/5693/109/5034/7314 38 Cucumber_mosaic_virus R-HSA-2559585 Oncogene Induced Senescence 15/1181 33/10654 6.424931054817901e-7 2.821189449330075e-6 1.2192274920998456e-6 1019/5594/5925/192670/7316/6667/1021/192669/7157/6233/7311/26523/7314/5595/4193 15 Cucumber_mosaic_virus R-HSA-389356 CD28 co-stimulation 15/1181 33/10654 6.424931054817901e-7 2.821189449330075e-6 1.2192274920998456e-6 5295/5170/5290/207/6714/64223/2534/208/2885/7525/79109/2475/3932/5879/253260 15 Cucumber_mosaic_virus R-HSA-389977 Post-chaperonin tubulin folding pathway 12/1181 22/10654 7.292504145174315e-7 3.191099227664209e-6 1.3790906205574658e-6 84617/7277/10381/7278/112714/6902/1155/7846/113457/10376/10383/84790 12 Cucumber_mosaic_virus R-HSA-450341 Activation of the AP-1 family of transcription factors 8/1181 10/10654 8.174562340189317e-7 3.564783371031011e-6 1.5405849083880027e-6 5601/5594/1432/5602/1386/5599/5600/5595 8 Cucumber_mosaic_virus R-HSA-9614085 FOXO-mediated transcription 22/1181 65/10654 8.782517839352686e-7 3.816786006211835e-6 1.6494923555525414e-6 5105/857/2309/207/10971/7295/4287/7534/847/1026/4089/1387/4088/6794/2033/3630/3066/3065/4087/208/23411/7529 22 Cucumber_mosaic_virus R-HSA-400253 Circadian Clock 23/1181 70/10654 9.045177646959725e-7 3.917518919451158e-6 1.6930258861383211e-6 8454/8945/1374/6500/3091/4209/7316/5469/5501/8553/4208/1387/150094/2033/5499/6233/1385/7311/1386/23411/1453/5500/7314 23 Cucumber_mosaic_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 31/1181 112/10654 9.150716300747574e-7 3.949747954302269e-6 1.7069542401322902e-6 5295/8454/8945/5684/5579/5336/4775/6500/5705/7316/10213/5970/6850/8915/5701/2534/5710/2280/5478/30011/5704/6233/2885/7311/808/3845/3265/801/5693/7314/805 31 Cucumber_mosaic_virus R-HSA-180024 DARPP-32 events 13/1181 26/10654 9.292381841149294e-7 3.9972991716672725e-6 1.7275043494161579e-6 5567/5568/5528/5566/5519/5499/5518/808/801/1020/805/5515/5516 13 Cucumber_mosaic_virus R-HSA-163615 PKA activation 11/1181 19/10654 9.647892897318132e-7 4.136208137397538e-6 1.7875363440621436e-6 5567/5568/114/108/107/5566/808/115/801/109/805 11 Cucumber_mosaic_virus R-HSA-72306 tRNA processing 30/1181 107/10654 1.0150875988687769e-6 4.337192467893864e-6 1.8743953181308977e-6 23165/4928/5903/55706/7175/9631/3028/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/9972/8021/129401/55746/51493/8480/54888/54517 30 Cucumber_mosaic_virus R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 16/1181 39/10654 1.481301446172979e-6 6.3016066860351085e-6 2.723352066214003e-6 10694/22803/10575/10528/7203/10576/908/6774/26330/26270/6950/55294/7157/10574/22948/6499 16 Cucumber_mosaic_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 25/1181 82/10654 1.489741533341633e-6 6.3016066860351085e-6 2.723352066214003e-6 8454/8945/5684/1499/1452/6500/5705/5528/7316/10213/9978/5519/2932/5701/324/5710/3065/5704/6233/7311/5518/5693/7314/5515/5516 25 Cucumber_mosaic_virus R-HSA-9013694 Signaling by NOTCH4 25/1181 82/10654 1.489741533341633e-6 6.3016066860351085e-6 2.723352066214003e-6 8454/5684/207/6500/5705/7534/7316/10213/9978/5664/22938/5701/1387/4088/2033/55294/5710/5704/6233/7311/3516/4851/5693/5663/7314 25 Cucumber_mosaic_virus R-HSA-69620 Cell Cycle Checkpoints 60/1181 293/10654 1.5067100778667895e-6 6.352209597385235e-6 2.7452210196488803e-6 1017/4928/5684/5903/54908/55143/7531/1058/8317/10971/63967/348995/11200/545/79023/472/57122/5705/6232/7534/580/1780/5528/7316/10213/4174/891/5501/890/983/1026/4171/23279/79902/9656/5519/5701/4683/22919/84126/5710/1111/7157/5984/5704/6233/672/7158/7311/5518/5983/9793/10726/55746/5693/7529/7314/4193/5515/5516 60 Cucumber_mosaic_virus R-HSA-73893 DNA Damage Bypass 18/1181 48/10654 1.5845866398888873e-6 6.658412072910589e-6 2.877551897462915e-6 124739/54107/9636/7706/8450/7316/9978/5111/7415/25898/5984/9246/6233/7311/5983/55666/7314/8451 18 Cucumber_mosaic_virus R-HSA-69242 S Phase 39/1181 161/10654 1.6064147755347727e-6 6.727855941101078e-6 2.9075633074643624e-6 8454/1017/2237/1019/5684/902/207/6500/54107/5925/5705/5885/7316/10213/5422/9978/4174/890/4331/1026/5111/4171/4609/2932/5701/6502/1874/9126/595/5710/5984/208/5704/6233/7311/5983/1022/5693/7314 39 Cucumber_mosaic_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 25/1181 83/10654 1.9106333662277783e-6 7.975637308365297e-6 3.4468143483541294e-6 8454/8945/5684/5579/4775/6500/5705/7316/10213/5970/8915/5701/5710/2280/5478/5704/6233/7311/808/3845/3265/801/5693/7314/805 25 Cucumber_mosaic_virus R-HSA-1236394 Signaling by ERBB4 20/1181 58/10654 1.9692421584828706e-6 8.193338685622173e-6 3.5408978932513394e-6 5295/5290/51741/348/7316/4734/10413/6714/2099/5664/3925/6285/6233/2885/7311/1956/3845/3265/5663/7314 20 Cucumber_mosaic_virus R-HSA-157858 Gap junction trafficking and regulation 18/1181 49/10654 2.2474663873603518e-6 9.320375312288518e-6 4.027966934347242e-6 84617/71/4646/1785/7277/10381/7278/112714/8218/7082/6714/7846/113457/10376/1213/10383/60/84790 18 Cucumber_mosaic_virus R-HSA-450604 KSRP (KHSRP) binds and destabilizes mRNA 10/1181 17/10654 2.5235838671439366e-6 1.0431361327054252e-5 4.508099416362047e-6 5073/207/7534/1432/51010/5600/56915/8570/54512/167227 10 Cucumber_mosaic_virus R-HSA-76071 RNA Polymerase III Transcription Initiation From Type 3 Promoter 13/1181 28/10654 2.702614231052518e-6 1.1135121620797549e-5 4.812242017697751e-6 5434/5440/5451/6617/5441/5435/5437/10302/6621/6908/7702/6619/6618 13 Cucumber_mosaic_virus R-HSA-198323 AKT phosphorylates targets in the cytosol 9/1181 14/10654 2.9255372051765187e-6 1.193732062176528e-5 5.158926667446154e-6 842/207/84335/7249/1026/2932/208/2931/4193 9 Cucumber_mosaic_virus R-HSA-3371568 Attenuation phase 9/1181 14/10654 2.9255372051765187e-6 1.193732062176528e-5 5.158926667446154e-6 3303/1387/3320/2033/3326/3306/3312/2288/10728 9 Cucumber_mosaic_virus R-HSA-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase 9/1181 14/10654 2.9255372051765187e-6 1.193732062176528e-5 5.158926667446154e-6 5567/5568/114/107/5566/1385/808/801/805 9 Cucumber_mosaic_virus R-HSA-5654736 Signaling by FGFR1 18/1181 50/10654 3.1511869737749615e-6 1.28168470183347e-5 5.539029734604436e-6 5295/5290/5335/5594/2260/7316/6714/8569/6233/2885/7311/5518/3845/3265/7314/5595/5515/5516 18 Cucumber_mosaic_virus R-HSA-9609736 Assembly and cell surface presentation of NMDA receptors 16/1181 41/10654 3.2637670803630006e-6 1.3232333626136256e-5 5.71858970529384e-6 818/84617/815/8573/817/7277/10381/7278/112714/7846/113457/10376/816/10383/84790/4747 16 Cucumber_mosaic_virus R-HSA-5610783 Degradation of GLI2 by the proteasome 20/1181 60/10654 3.595162936661816e-6 1.4483370687694744e-5 6.259247752717816e-6 8454/8945/5684/5567/1452/5568/6500/5705/7316/10213/9978/5566/2932/5701/5710/5704/6233/7311/5693/7314 20 Cucumber_mosaic_virus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 20/1181 60/10654 3.595162936661816e-6 1.4483370687694744e-5 6.259247752717816e-6 8454/8945/5684/5567/1452/5568/6500/5705/7316/10213/9978/5566/2932/5701/5710/5704/6233/7311/5693/7314 20 Cucumber_mosaic_virus R-HSA-389513 CTLA4 inhibitory signaling 11/1181 21/10654 3.6458202646662936e-6 1.4548886527866436e-5 6.287561595137832e-6 207/5528/6714/5519/2534/208/7525/3932/5518/5515/5516 11 Cucumber_mosaic_virus R-HSA-5218921 VEGFR2 mediated cell proliferation 11/1181 21/10654 3.6458202646662936e-6 1.4548886527866436e-5 6.287561595137832e-6 5170/5590/5335/5579/5578/6714/808/3845/3265/801/805 11 Cucumber_mosaic_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 11/1181 21/10654 3.6458202646662936e-6 1.4548886527866436e-5 6.287561595137832e-6 9252/5567/5568/5970/5566/1387/2534/2033/5894/3845/3265 11 Cucumber_mosaic_virus R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 13/1181 29/10654 4.403365175635737e-6 1.751683513442555e-5 7.570213682581155e-6 5434/5440/5430/5436/5441/5438/5431/5435/5433/5437/3320/5439/5432 13 Cucumber_mosaic_virus R-HSA-202424 Downstream TCR signaling 27/1181 98/10654 5.02169317547635e-6 1.9914151998998402e-5 8.606257054023614e-6 5295/8454/5170/8945/5684/5290/6500/3123/5705/7316/10213/3122/920/5970/8915/7322/5701/5728/5710/7189/5704/6233/7311/3932/5693/997/7314 27 Cucumber_mosaic_virus R-HSA-190840 Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane 10/1181 18/10654 5.113700899694366e-6 2.0153063483578107e-5 8.709506926252908e-6 84617/7277/10381/7278/112714/7846/113457/10376/10383/84790 10 Cucumber_mosaic_virus R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 10/1181 18/10654 5.113700899694366e-6 2.0153063483578107e-5 8.709506926252908e-6 5578/5594/6195/2885/1385/1956/6197/3845/3265/5595 10 Cucumber_mosaic_virus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 25/1181 88/10654 6.159535019636219e-6 2.419953541770391e-5 1.0458262164674825e-5 8454/8945/7531/4659/11190/203068/55125/6500/7277/7316/891/983/1639/5566/7846/3320/22919/6233/7311/5518/10383/1453/9793/5500/7314 25 Cucumber_mosaic_virus R-HSA-447115 Interleukin-12 family signaling 19/1181 57/10654 6.278741394569933e-6 2.4591737128732235e-5 1.062775915065281e-5 1072/9049/4478/3313/6175/6774/6772/6647/6950/3181/9244/5478/4001/6888/302/4282/5034/829/3572 19 Cucumber_mosaic_virus R-HSA-187687 Signalling to ERKs 14/1181 34/10654 6.403196852897783e-6 2.4900268785961792e-5 1.0761096626009783e-5 5594/6714/5605/1432/4914/5603/2885/5906/3845/5600/3265/6300/7529/5595 14 Cucumber_mosaic_virus R-HSA-389357 CD28 dependent PI3K/Akt signaling 11/1181 22/10654 6.5623901148152035e-6 2.4900268785961792e-5 1.0761096626009783e-5 5295/5170/5290/207/64223/2534/208/79109/2475/3932/253260 11 Cucumber_mosaic_virus R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 11/1181 22/10654 6.5623901148152035e-6 2.4900268785961792e-5 1.0761096626009783e-5 4000/351/2309/7531/823/7001/824/4001/8851/5052/1020 11 Cucumber_mosaic_virus R-HSA-8863678 Neurodegenerative Diseases 11/1181 22/10654 6.5623901148152035e-6 2.4900268785961792e-5 1.0761096626009783e-5 4000/351/2309/7531/823/7001/824/4001/8851/5052/1020 11 Cucumber_mosaic_virus R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 9/1181 15/10654 6.592978969332673e-6 2.4900268785961792e-5 1.0761096626009783e-5 1499/1452/5528/5519/2932/324/5518/5515/5516 9 Cucumber_mosaic_virus R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 9/1181 15/10654 6.592978969332673e-6 2.4900268785961792e-5 1.0761096626009783e-5 1499/1452/5528/5519/2932/324/5518/5515/5516 9 Cucumber_mosaic_virus R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 9/1181 15/10654 6.592978969332673e-6 2.4900268785961792e-5 1.0761096626009783e-5 1499/1452/5528/5519/2932/324/5518/5515/5516 9 Cucumber_mosaic_virus R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 9/1181 15/10654 6.592978969332673e-6 2.4900268785961792e-5 1.0761096626009783e-5 1499/1452/5528/5519/2932/324/5518/5515/5516 9 Cucumber_mosaic_virus R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 9/1181 15/10654 6.592978969332673e-6 2.4900268785961792e-5 1.0761096626009783e-5 1499/1452/5528/5519/2932/324/5518/5515/5516 9 Cucumber_mosaic_virus R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 9/1181 15/10654 6.592978969332673e-6 2.4900268785961792e-5 1.0761096626009783e-5 1499/1452/5528/5519/2932/324/5518/5515/5516 9 Cucumber_mosaic_virus R-HSA-5637810 Constitutive Signaling by EGFRvIII 9/1181 15/10654 6.592978969332673e-6 2.4900268785961792e-5 1.0761096626009783e-5 5295/5290/5335/3320/2885/1956/3845/3265/11140 9 Cucumber_mosaic_virus R-HSA-5637812 Signaling by EGFRvIII in Cancer 9/1181 15/10654 6.592978969332673e-6 2.4900268785961792e-5 1.0761096626009783e-5 5295/5290/5335/3320/2885/1956/3845/3265/11140 9 Cucumber_mosaic_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 12/1181 26/10654 7.125120477448615e-6 2.6830201441787217e-5 1.1595151550056936e-5 10273/7316/5501/4088/9958/4087/5499/6233/7311/7040/5500/7314 12 Cucumber_mosaic_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 23/1181 78/10654 7.2680570846714605e-6 2.728746875872214e-5 1.1792767801662506e-5 351/7186/9636/841/7706/9474/7316/5970/7322/1387/843/2033/9246/7189/6285/51191/6233/7311/5094/8772/5300/1540/7314 23 Cucumber_mosaic_virus R-HSA-9634600 Regulation of glycolysis by fructose 2,6-bisphosphate metabolism 8/1181 12/10654 7.322055587118497e-6 2.740911073762057e-5 1.1845337559039705e-5 5567/5568/5528/5566/5519/5518/5515/5516 8 Cucumber_mosaic_virus R-HSA-5687128 MAPK6/MAPK4 signaling 25/1181 89/10654 7.67781436795895e-6 2.8656313038058553e-5 1.2384338345840906e-5 27161/5684/2309/10642/5567/5568/3315/5705/192670/7316/10213/983/4609/5566/5701/5710/192669/896/5704/6233/7311/26523/5693/7314/5879 25 Cucumber_mosaic_virus R-HSA-157118 Signaling by NOTCH 49/1181 235/10654 8.150439784968527e-6 3.0331108759897537e-5 1.3108131279421523e-5 8454/27161/5684/23509/5584/892/207/4904/6500/3091/10013/5705/192670/7534/488/7316/10213/9978/3714/9759/6772/4609/5664/11060/10014/22938/5701/1387/4088/2033/595/55294/5710/192669/3066/3065/7157/861/5704/6233/1385/7311/1956/26523/3516/4851/5693/5663/7314 49 Cucumber_mosaic_virus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 15/1181 39/10654 8.174618586786662e-6 3.033213738781367e-5 1.3108575819377811e-5 124739/54107/9636/7706/7316/5111/7415/25898/5984/9246/6233/7311/5983/55666/7314 15 Cucumber_mosaic_virus R-HSA-110320 Translesion Synthesis by POLH 10/1181 19/10654 9.723602688541656e-6 3.5869918057440004e-5 1.550182680761996e-5 7316/5111/7415/25898/5984/6233/7311/5983/55666/7314 10 Cucumber_mosaic_virus R-HSA-190872 Transport of connexons to the plasma membrane 10/1181 19/10654 9.723602688541656e-6 3.5869918057440004e-5 1.550182680761996e-5 84617/7277/10381/7278/112714/7846/113457/10376/10383/84790 10 Cucumber_mosaic_virus R-HSA-5654733 Negative regulation of FGFR4 signaling 13/1181 31/10654 1.0816447632625717e-5 3.978571607478851e-5 1.719410897512738e-5 5594/7316/6714/8569/2264/6233/2885/7311/5518/7314/5595/5515/5516 13 Cucumber_mosaic_virus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 11/1181 23/10654 1.1321018518740405e-5 4.1521307804282006e-5 1.7944175991067087e-5 51592/7316/4089/4088/142/5494/3065/4087/6233/7311/7314 11 Cucumber_mosaic_virus R-HSA-205043 NRIF signals cell death from the nucleus 9/1181 16/10654 1.3586051193078127e-5 4.968501142367765e-5 2.147226656027212e-5 8878/7316/5664/7189/6233/7311/5599/5663/7314 9 Cucumber_mosaic_virus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 19/1181 60/10654 1.4561268046132135e-5 5.30984170992577e-5 2.2947430889397587e-5 8454/1017/1019/5684/6500/5705/7316/10213/890/1026/5701/6502/595/5710/5704/6233/7311/5693/7314 19 Cucumber_mosaic_virus R-HSA-9639288 Amino acids regulate mTORC1 18/1181 55/10654 1.4642011701017713e-5 5.323986489567759e-5 2.3008560085146218e-5 51606/389541/79726/58528/153129/64223/10325/84219/8649/6009/10542/2475/55004/10670/201163/64121/57521/28956 18 Cucumber_mosaic_virus R-HSA-2871796 FCERI mediated MAPK activation 13/1181 32/10654 1.6379393621842996e-5 5.921780770974006e-5 2.5592035018684064e-5 5601/5335/5336/5594/6850/5602/5609/2885/3845/5599/3265/5879/5595 13 Cucumber_mosaic_virus R-HSA-8941326 RUNX2 regulates bone development 13/1181 32/10654 1.6379393621842996e-5 5.921780770974006e-5 2.5592035018684064e-5 25/5594/4086/5925/10013/9759/10413/6714/4089/7525/367/10432/5595 13 Cucumber_mosaic_virus R-HSA-202670 ERKs are inactivated 8/1181 13/10654 1.7182599817752862e-5 6.142174413726305e-5 2.6544505574645637e-5 1849/5594/5528/5519/5518/5595/5515/5516 8 Cucumber_mosaic_virus R-HSA-203615 eNOS activation 8/1181 13/10654 1.7182599817752862e-5 6.142174413726305e-5 2.6544505574645637e-5 857/23564/207/3320/4846/808/801/805 8 Cucumber_mosaic_virus R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 8/1181 13/10654 1.7182599817752862e-5 6.142174413726305e-5 2.6544505574645637e-5 7531/10971/11200/7534/891/983/1111/7529 8 Cucumber_mosaic_virus R-HSA-879415 Advanced glycosylation endproduct receptor signaling 8/1181 13/10654 1.7182599817752862e-5 6.142174413726305e-5 2.6544505574645637e-5 351/1650/5594/830/3958/6285/829/5595 8 Cucumber_mosaic_virus R-HSA-5625900 RHO GTPases activate CIT 10/1181 20/10654 1.7517999492146483e-5 6.226986374099127e-5 2.6911035634404594e-5 4659/4627/10627/4637/79784/11113/4628/103910/5500/5879 10 Cucumber_mosaic_virus R-HSA-8876384 Listeria monocytogenes entry into host cells 10/1181 20/10654 1.7517999492146483e-5 6.226986374099127e-5 2.6911035634404594e-5 1499/7316/6714/999/9146/30011/6233/2885/7311/7314 10 Cucumber_mosaic_virus R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 19/1181 61/10654 1.897799486467718e-5 6.727116056780821e-5 2.907243553218704e-5 25/1072/71/10093/4627/5594/4644/6850/10094/10152/4641/3320/2885/10096/3326/23191/60/5879/5595 19 Cucumber_mosaic_virus R-HSA-5693532 DNA Double-Strand Break Repair 37/1181 166/10654 2.2490208105277426e-5 7.949881360890544e-5 3.435683454874517e-5 1017/25/3838/2237/5893/675/63967/54107/11200/545/472/6613/3981/580/5591/7316/890/5111/7517/9656/22976/4683/84126/142/1111/7157/5984/6233/672/7158/7311/6047/5536/5983/5599/2547/7314 37 Cucumber_mosaic_virus R-HSA-5654726 Negative regulation of FGFR1 signaling 13/1181 33/10654 2.4301380649831608e-5 8.566236679065642e-5 3.702052432328149e-5 5594/2260/7316/6714/8569/6233/2885/7311/5518/7314/5595/5515/5516 13 Cucumber_mosaic_virus R-HSA-190828 Gap junction trafficking 16/1181 47/10654 2.496174485456593e-5 8.774641058294782e-5 3.7921181132027554e-5 84617/71/4646/1785/7277/10381/7278/112714/8218/7846/113457/10376/1213/10383/60/84790 16 Cucumber_mosaic_virus R-HSA-196299 Beta-catenin phosphorylation cascade 9/1181 17/10654 2.603132693475401e-5 9.075207109945835e-5 3.922013109602903e-5 1499/1452/5528/5519/2932/324/5518/5515/5516 9 Cucumber_mosaic_virus R-HSA-202131 Metabolism of nitric oxide: eNOS activation and regulation 9/1181 17/10654 2.603132693475401e-5 9.075207109945835e-5 3.922013109602903e-5 857/23564/207/1785/3320/4846/808/801/805 9 Cucumber_mosaic_virus R-HSA-9034015 Signaling by NTRK3 (TRKC) 9/1181 17/10654 2.603132693475401e-5 9.075207109945835e-5 3.922013109602903e-5 5295/5290/3667/5335/6714/2885/3845/3265/25920 9 Cucumber_mosaic_virus R-HSA-5654732 Negative regulation of FGFR3 signaling 12/1181 29/10654 2.7874207464408626e-5 9.691060074612204e-5 4.188164986000546e-5 5594/7316/6714/8569/6233/2885/7311/5518/7314/5595/5515/5516 12 Cucumber_mosaic_virus R-HSA-5689896 Ovarian tumor domain proteases 14/1181 38/10654 2.901871378870429e-5 1.0033991225576498e-4 4.3363688179879346e-5 55611/7706/7316/983/2099/7415/324/5728/7157/7189/6233/7311/54764/7314 14 Cucumber_mosaic_virus R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 14/1181 38/10654 2.901871378870429e-5 1.0033991225576498e-4 4.3363688179879346e-5 1072/9049/4478/3313/6175/6647/6950/3181/5478/4001/6888/302/4282/829 14 Cucumber_mosaic_virus R-HSA-202403 TCR signaling 29/1181 119/10654 3.0134859310754186e-5 1.0372941027576732e-4 4.482852038793478e-5 5295/8454/5170/8945/5684/5290/5335/6500/3123/5705/7316/10213/3122/920/5970/8915/7322/5701/5728/1445/5710/7189/5704/6233/7311/3932/5693/997/7314 29 Cucumber_mosaic_virus R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 11/1181 25/10654 3.024419369742625e-5 1.0372941027576732e-4 4.482852038793478e-5 1017/902/891/890/4331/983/5519/5518/1022/5515/5516 11 Cucumber_mosaic_virus R-HSA-9006115 Signaling by NTRK2 (TRKB) 11/1181 25/10654 3.024419369742625e-5 1.0372941027576732e-4 4.482852038793478e-5 5295/5290/5335/6714/2534/2885/8851/3845/3265/1020/5879 11 Cucumber_mosaic_virus R-HSA-163685 Integration of energy metabolism 27/1181 108/10654 3.460902590195206e-5 1.1837966002581444e-4 5.115988791294374e-5 5563/5313/5567/5578/5568/51422/114/108/5528/107/5566/5519/6794/2783/3630/7086/8826/5906/6888/5518/115/31/5565/109/6812/5515/5516 27 Cucumber_mosaic_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 13/1181 34/10654 3.538120871460023e-5 1.2069557488932174e-4 5.216075195332971e-5 9636/7706/9474/7316/7322/9246/51191/6233/7311/5094/5300/1540/7314 13 Cucumber_mosaic_virus R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 8/1181 14/10654 3.619201663452125e-5 1.2150177013017849e-4 5.250916364963958e-5 1452/5528/5519/2932/324/5518/5515/5516 8 Cucumber_mosaic_virus R-HSA-4839744 truncated APC mutants destabilize the destruction complex 8/1181 14/10654 3.619201663452125e-5 1.2150177013017849e-4 5.250916364963958e-5 1452/5528/5519/2932/324/5518/5515/5516 8 Cucumber_mosaic_virus R-HSA-4839748 AMER1 mutants destabilize the destruction complex 8/1181 14/10654 3.619201663452125e-5 1.2150177013017849e-4 5.250916364963958e-5 1452/5528/5519/2932/324/5518/5515/5516 8 Cucumber_mosaic_virus R-HSA-5467337 APC truncation mutants have impaired AXIN binding 8/1181 14/10654 3.619201663452125e-5 1.2150177013017849e-4 5.250916364963958e-5 1452/5528/5519/2932/324/5518/5515/5516 8 Cucumber_mosaic_virus R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 8/1181 14/10654 3.619201663452125e-5 1.2150177013017849e-4 5.250916364963958e-5 1452/5528/5519/2932/324/5518/5515/5516 8 Cucumber_mosaic_virus R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 8/1181 14/10654 3.619201663452125e-5 1.2150177013017849e-4 5.250916364963958e-5 1452/5528/5519/2932/324/5518/5515/5516 8 Cucumber_mosaic_virus R-HSA-5619115 Disorders of transmembrane transporters 38/1181 176/10654 3.7160091984148214e-5 1.2442257711842765e-4 5.3771442643358474e-5 23165/4928/5684/5903/55706/7175/9631/1080/348995/79023/57122/5705/23636/10762/23511/7316/10213/53371/23279/4927/9688/7415/79902/9883/5701/23225/5710/8086/5704/6233/7311/9972/8021/129401/55746/5693/8480/7314 38 Cucumber_mosaic_virus R-HSA-8948751 Regulation of PTEN stability and activity 20/1181 69/10654 3.73354487949491e-5 1.2468074873892213e-4 5.388301612789053e-5 5684/10273/207/1460/5705/7316/10213/1457/4734/11060/5701/5728/5710/5987/208/5704/6233/7311/5693/7314 20 Cucumber_mosaic_virus R-HSA-1852241 Organelle biogenesis and maintenance 56/1181 296/10654 3.818969153067645e-5 1.2719873635807981e-4 5.4971209524747696e-5 10694/5563/84617/7531/11190/203068/3418/10575/55125/51422/7277/10013/53632/10381/7278/3313/112714/4209/5147/7203/10576/5469/10989/83658/983/1639/5566/132320/1432/5571/4208/1387/6950/7846/113457/3320/22919/10376/1385/5518/10383/1386/84790/22948/378/808/5600/1453/5564/6300/801/9793/5565/57787/814/805 56 Cucumber_mosaic_virus R-HSA-76002 Platelet activation, signaling and aggregation 51/1181 262/10654 3.8716107358656145e-5 1.286145032411902e-4 5.558305851160059e-5 5295/5170/5590/351/1072/5290/5579/5340/5336/2316/207/5578/5594/5582/7277/29106/7534/5216/6850/6714/710/6647/1191/1432/23052/3920/226/81/3309/9948/2335/2534/2783/1445/87/5894/5478/2/2885/8407/5906/3932/5581/7040/808/801/2147/5879/5595/805/2814 51 Cucumber_mosaic_virus R-HSA-1234174 Cellular response to hypoxia 21/1181 75/10654 4.253936824638998e-5 1.4094636633072815e-4 6.091249376492835e-5 5684/112399/3091/5705/7316/10213/9978/8994/7322/5701/1387/2033/5710/8453/5704/6233/7311/55662/405/5693/7314 21 Cucumber_mosaic_virus R-HSA-9604323 Negative regulation of NOTCH4 signaling 17/1181 54/10654 4.437291337985557e-5 1.4651054730444648e-4 6.33171541168899e-5 8454/5684/207/6500/5705/7534/7316/10213/9978/5701/55294/5710/5704/6233/7311/5693/7314 17 Cucumber_mosaic_virus R-HSA-376172 DSCAM interactions 7/1181 11/10654 4.456506797440216e-5 1.4651054730444648e-4 6.33171541168899e-5 1432/5603/1630/5599/5600/6300/5879 7 Cucumber_mosaic_virus R-HSA-5655291 Signaling by FGFR4 in disease 7/1181 11/10654 4.456506797440216e-5 1.4651054730444648e-4 6.33171541168899e-5 5295/5290/5335/2264/2885/3845/3265 7 Cucumber_mosaic_virus R-HSA-177929 Signaling by EGFR 16/1181 49/10654 4.4854223696993784e-5 1.46701056369807e-4 6.339948601772588e-5 5295/5290/5335/7316/6714/9146/1445/30011/6233/2885/7311/1956/8874/3845/3265/7314 16 Cucumber_mosaic_virus R-HSA-9012852 Signaling by NOTCH3 16/1181 49/10654 4.4854223696993784e-5 1.46701056369807e-4 6.339948601772588e-5 4904/7316/3714/6772/5664/11060/22938/1387/2033/6233/7311/1956/3516/4851/5663/7314 16 Cucumber_mosaic_virus R-HSA-199418 Negative regulation of the PI3K/AKT network 27/1181 110/10654 4.8986136268476254e-5 1.5980310263418089e-4 6.906176970877047e-5 5295/5290/3667/6801/207/5594/2260/5528/2100/6714/2099/5519/2534/5728/2264/3630/7189/208/2885/3932/5518/1956/5156/5879/5595/5515/5516 27 Cucumber_mosaic_virus R-HSA-442982 Ras activation upon Ca2+ influx through NMDA receptor 10/1181 22/10654 4.976797268572239e-5 1.6152316454777932e-4 6.980512523694001e-5 818/815/817/816/808/3845/3265/801/4747/805 10 Cucumber_mosaic_virus R-HSA-912631 Regulation of signaling by CBL 10/1181 22/10654 4.976797268572239e-5 1.6152316454777932e-4 6.980512523694001e-5 5295/5290/7316/6850/2534/6233/2885/7525/7311/7314 10 Cucumber_mosaic_virus R-HSA-5610780 Degradation of GLI1 by the proteasome 18/1181 60/10654 5.479411750070329e-5 1.7738197731732773e-4 7.665879489222989e-5 8454/8945/5684/5567/5568/6500/5705/7316/10213/9978/5566/5701/5710/5704/6233/7311/5693/7314 18 Cucumber_mosaic_virus R-HSA-5619102 SLC transporter disorders 25/1181 99/10654 5.582740183136116e-5 1.8026710667683795e-4 7.790565516041025e-5 23165/4928/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 25 Cucumber_mosaic_virus R-HSA-381119 Unfolded Protein Response (UPR) 24/1181 94/10654 6.463430568740598e-5 2.0817495918101062e-4 8.996653289644274e-5 4000/440/10488/1965/2673/5073/116138/118/811/1051/58477/22872/1639/3068/8894/3309/2931/51010/56915/8570/54512/167227/9820/1968 24 Cucumber_mosaic_virus R-HSA-4419969 Depolymerisation of the Nuclear Lamina 8/1181 15/10654 7.001948825187965e-5 2.249486850421146e-4 9.721559861220333e-5 4000/5579/5578/891/983/2010/4001/7112 8 Cucumber_mosaic_virus R-HSA-76046 RNA Polymerase III Transcription Initiation 13/1181 36/10654 7.126195419180518e-5 2.283621713873757e-4 9.869079780417464e-5 5434/5440/5451/6617/5441/5435/5437/10302/6621/6908/7702/6619/6618 13 Cucumber_mosaic_virus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 17/1181 56/10654 7.437096642890344e-5 2.3772482719969386e-4 1.0273703701301521e-4 3303/5684/3184/3315/26986/5705/7316/10213/5701/1981/5710/5704/6233/7311/3312/5693/7314 17 Cucumber_mosaic_virus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 10/1181 23/10654 7.934255281417047e-5 2.5297914452558374e-4 1.0932946314779904e-4 5601/7316/5602/10454/7189/5609/6233/7311/5599/7314 10 Cucumber_mosaic_virus R-HSA-6804760 Regulation of TP53 Activity through Methylation 9/1181 19/10654 8.045176822295833e-5 2.558729169797848e-4 1.105800586839765e-4 11200/472/7316/2033/7157/6233/7311/7314/4193 9 Cucumber_mosaic_virus R-HSA-5688426 Deubiquitination 55/1181 297/10654 8.174926047696762e-5 2.593495288631798e-4 1.1208253870657929e-4 5684/7186/7375/55611/63967/4086/1080/3091/5705/4287/7706/86/580/7316/10213/890/7417/983/8678/2099/4609/7415/4089/5701/329/6502/7347/4088/9146/324/2033/5728/5710/10454/8473/7157/9958/4087/63891/7189/5704/6233/672/7311/367/60/23770/7040/8607/7345/1540/54764/5693/7314/4193 55 Cucumber_mosaic_virus R-HSA-381042 PERK regulates gene expression 12/1181 32/10654 8.836172571020591e-5 2.789329102643067e-4 1.20545847329189e-4 440/1965/5073/1051/8894/3309/51010/56915/8570/54512/167227/1968 12 Cucumber_mosaic_virus R-HSA-5656169 Termination of translesion DNA synthesis 12/1181 32/10654 8.836172571020591e-5 2.789329102643067e-4 1.20545847329189e-4 124739/54107/9636/7706/7316/5111/5984/9246/6233/7311/5983/7314 12 Cucumber_mosaic_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 20/1181 73/10654 8.99910417650821e-5 2.8337129528508483e-4 1.2246397481940126e-4 8454/5684/10273/6500/5705/7316/10213/9978/6772/2099/2932/5701/6502/55294/5710/5704/6233/7311/5693/7314 20 Cucumber_mosaic_virus R-HSA-3371511 HSF1 activation 7/1181 12/10654 9.670528531659937e-5 3.037599184820906e-4 1.3127528309001633e-4 7531/1915/10013/7415/3320/3326/10728 7 Cucumber_mosaic_virus R-HSA-69615 G1/S DNA Damage Checkpoints 19/1181 68/10654 1.0048525321274995e-4 3.148537933999498e-4 1.3606969960712858e-4 1017/5684/11200/472/5705/7316/10213/890/1026/5701/5710/1111/7157/5704/6233/7311/5693/7314/4193 19 Cucumber_mosaic_virus R-HSA-9020591 Interleukin-12 signaling 15/1181 47/10654 1.0381927496936544e-4 3.244991624042481e-4 1.4023811837967176e-4 1072/9049/4478/3313/6175/6647/6950/3181/5478/4001/6888/302/4282/5034/829 15 Cucumber_mosaic_virus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 25/1181 103/10654 1.118579670233958e-4 3.4876599546115303e-4 1.507254644230938e-4 5295/5290/3667/6801/207/5594/2260/5528/2100/6714/2099/5519/2534/2264/3630/7189/2885/3932/5518/1956/5156/5879/5595/5515/5516 25 Cucumber_mosaic_virus R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 10/1181 24/10654 1.2257754713232153e-4 3.812522238012648e-4 1.6476496918457049e-4 5590/5579/5578/5594/5289/1432/5300/5600/5879/5595 10 Cucumber_mosaic_virus R-HSA-193639 p75NTR signals via NF-kB 8/1181 16/10654 1.2645292531068166e-4 3.92344161905269e-4 1.6955854867292536e-4 5584/8878/7316/5970/7189/6233/7311/7314 8 Cucumber_mosaic_virus R-HSA-2682334 EPH-Ephrin signaling 23/1181 92/10654 1.2891079681752687e-4 3.9899463697912587e-4 1.7243267045425288e-4 1072/28964/71/10093/4627/10627/8218/10094/6714/5664/4637/79784/2534/4628/7525/10096/1213/103910/60/8874/3265/5663/5879 23 Cucumber_mosaic_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 16/1181 53/10654 1.29534389814868e-4 3.999492473845924e-4 1.7284522241912208e-4 7531/842/207/10971/5594/841/7534/6774/4836/836/7157/208/840/5599/7529/5595 16 Cucumber_mosaic_virus R-HSA-167044 Signalling to RAS 9/1181 20/10654 1.3194303354816802e-4 4.0541334036955256e-4 1.752066279561502e-4 6714/1432/4914/5603/2885/3845/5600/3265/6300 9 Cucumber_mosaic_virus R-HSA-5627117 RHO GTPases Activate ROCKs 9/1181 20/10654 1.3194303354816802e-4 4.0541334036955256e-4 1.752066279561502e-4 1072/4659/4627/10627/4637/79784/4628/103910/5500 9 Cucumber_mosaic_virus R-HSA-1433557 Signaling by SCF-KIT 14/1181 43/10654 1.3812689768947858e-4 4.2338896900470603e-4 1.829751174579668e-4 5295/5290/5578/6774/6772/6714/2534/1111/2885/7525/3932/3845/3265/5879 14 Cucumber_mosaic_virus R-HSA-8863795 Downregulation of ERBB2 signaling 11/1181 29/10654 1.5433590813827592e-4 4.7193317452402924e-4 2.039543643374553e-4 8065/10273/207/7316/3320/208/6233/7311/1956/11140/7314 11 Cucumber_mosaic_virus R-HSA-69481 G2/M Checkpoints 35/1181 168/10654 1.5771249295333994e-4 4.8109892682160667e-4 2.079155081697624e-4 1017/5684/7531/8317/10971/63967/11200/545/472/5705/7534/580/7316/10213/4174/891/983/4171/9656/5701/4683/84126/5710/1111/7157/5984/5704/6233/672/7158/7311/5983/5693/7529/7314 35 Cucumber_mosaic_virus R-HSA-212165 Epigenetic regulation of gene expression 32/1181 149/10654 1.6524840012049032e-4 0.00050091232026059035 2.1647822060948742e-4 23451/5252/5434/5440/902/25885/404672/5441/11335/5435/4331/4641/1108/2966/2932/5437/2965/2033/2068/3066/3065/2071/1107/54790/2968/2967/6908/23411/60/8726/1022/9188 32 Cucumber_mosaic_virus R-HSA-8848021 Signaling by PTK6 16/1181 54/10654 1.653918535769798e-4 0.00050091232026059035 2.1647822060948742e-4 120892/1017/1019/207/3091/7316/6774/6421/595/6233/7311/1956/3845/3265/7314/5879 16 Cucumber_mosaic_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 16/1181 54/10654 1.653918535769798e-4 0.00050091232026059035 2.1647822060948742e-4 120892/1017/1019/207/3091/7316/6774/6421/595/6233/7311/1956/3845/3265/7314/5879 16 Cucumber_mosaic_virus R-HSA-2871837 FCERI mediated NF-kB activation 21/1181 82/10654 1.7356161674637495e-4 5.239763147454395e-4 2.264457384450035e-4 8454/5170/8945/5684/6500/5705/7316/10213/5970/8915/7322/5701/5710/10454/7189/5704/6233/7311/5693/997/7314 21 Cucumber_mosaic_virus R-HSA-5654727 Negative regulation of FGFR2 signaling 12/1181 34/10654 1.738329617871001e-4 5.239763147454395e-4 2.264457384450035e-4 5594/7316/6714/8569/6233/2885/7311/5518/7314/5595/5515/5516 12 Cucumber_mosaic_virus R-HSA-6798695 Neutrophil degranulation 79/1181 480/10654 1.7737287624148637e-4 5.333795733422896e-4 2.3050952487357047e-4 10694/2512/3303/1727/2934/3837/56954/5036/8621/9218/10159/1938/1915/11333/5315/203068/1650/23197/823/427/654364/5594/4831/2268/5211/6727/1460/10549/3958/54509/4257/847/10213/10576/1509/2896/1315/9588/7415/5337/1432/5701/6793/3920/226/2171/3310/2821/8649/55832/3320/4860/5478/10075/8566/51071/3326/6709/55004/23191/8826/5906/302/10383/5236/4282/3608/51806/3312/230/2547/5663/7879/1654/5879/28956/2950/5223/30 79 Cucumber_mosaic_virus R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 23/1181 94/10654 1.8246147157209322e-4 5.473844147162797e-4 2.3656196762239786e-4 4926/84617/7531/11190/203068/55125/7277/10381/7278/112714/983/1639/5566/7846/113457/3320/22919/10376/5518/10383/84790/1453/9793 23 Cucumber_mosaic_virus R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus 10/1181 25/10654 1.841331160889187e-4 5.510965196151835e-4 2.3816622016466398e-4 4904/7316/3714/5664/11060/6233/7311/1956/5663/7314 10 Cucumber_mosaic_virus R-HSA-68949 Orc1 removal from chromatin 19/1181 71/10654 1.8801995695831206e-4 5.578940671642847e-4 2.411039019473206e-4 8454/1017/5684/6500/5705/7316/10213/9978/4174/890/4171/5701/6502/5710/5704/6233/7311/5693/7314 19 Cucumber_mosaic_virus R-HSA-171007 p38MAPK events 7/1181 13/10654 1.894817517319202e-4 5.578940671642847e-4 2.411039019473206e-4 6714/1432/5603/3845/5600/3265/6300 7 Cucumber_mosaic_virus R-HSA-209543 p75NTR recruits signalling complexes 7/1181 13/10654 1.894817517319202e-4 5.578940671642847e-4 2.411039019473206e-4 5584/8878/7316/7189/6233/7311/7314 7 Cucumber_mosaic_virus R-HSA-209560 NF-kB is activated and signals survival 7/1181 13/10654 1.894817517319202e-4 5.578940671642847e-4 2.411039019473206e-4 8878/7316/5970/7189/6233/7311/7314 7 Cucumber_mosaic_virus R-HSA-2995383 Initiation of Nuclear Envelope Reformation 7/1181 13/10654 1.894817517319202e-4 5.578940671642847e-4 2.411039019473206e-4 4000/8815/2010/4001/5518/7112/5515 7 Cucumber_mosaic_virus R-HSA-2995410 Nuclear Envelope Reassembly 7/1181 13/10654 1.894817517319202e-4 5.578940671642847e-4 2.411039019473206e-4 4000/8815/2010/4001/5518/7112/5515 7 Cucumber_mosaic_virus R-HSA-5210891 Uptake and function of anthrax toxins 7/1181 13/10654 1.894817517319202e-4 5.578940671642847e-4 2.411039019473206e-4 5606/10015/5605/5609/808/801/805 7 Cucumber_mosaic_virus R-HSA-445144 Signal transduction by L1 9/1181 21/10654 2.0830350507144809e-4 6.118915461473788e-4 2.644398785141921e-4 5594/1460/2260/4684/1457/5605/1956/5879/5595 9 Cucumber_mosaic_virus R-HSA-69563 p53-Dependent G1 DNA Damage Response 18/1181 66/10654 2.126204002559214e-4 6.216942118082126e-4 2.6867627585092183e-4 1017/5684/11200/472/5705/7316/10213/890/1026/5701/5710/7157/5704/6233/7311/5693/7314/4193 18 Cucumber_mosaic_virus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 18/1181 66/10654 2.126204002559214e-4 6.216942118082126e-4 2.6867627585092183e-4 1017/5684/11200/472/5705/7316/10213/890/1026/5701/5710/7157/5704/6233/7311/5693/7314/4193 18 Cucumber_mosaic_virus R-HSA-164378 PKA activation in glucagon signalling 8/1181 17/10654 2.157165683115053e-4 6.292972992811499e-4 2.7196208612291413e-4 5567/5568/114/108/107/5566/115/109 8 Cucumber_mosaic_virus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 11/1181 30/10654 2.194883498897827e-4 6.359148767354662e-4 2.7482199060941304e-4 54107/8450/7316/9978/5111/5984/6233/7311/5983/7314/8451 11 Cucumber_mosaic_virus R-HSA-2424491 DAP12 signaling 11/1181 30/10654 2.194883498897827e-4 6.359148767354662e-4 2.7482199060941304e-4 5295/5290/5335/5336/6850/2534/2885/3932/3845/3265/5879 11 Cucumber_mosaic_virus R-HSA-6804758 Regulation of TP53 Activity through Acetylation 11/1181 30/10654 2.194883498897827e-4 6.359148767354662e-4 2.7482199060941304e-4 207/84289/1108/2033/3066/3065/7157/1107/5371/208/5300 11 Cucumber_mosaic_virus R-HSA-2465910 MASTL Facilitates Mitotic Progression 6/1181 10/10654 2.5923753728697706e-4 7.476646245844861e-4 3.231166433648685e-4 891/983/5519/5518/5515/5516 6 Cucumber_mosaic_virus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 6/1181 10/10654 2.5923753728697706e-4 7.476646245844861e-4 3.231166433648685e-4 7316/10454/7189/6233/7311/7314 6 Cucumber_mosaic_virus R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 15/1181 51/10654 2.8751865298111217e-4 8.273495932721799e-4 3.57553928161259e-4 84617/830/7277/10381/7278/112714/1780/1639/832/7846/113457/10376/10383/84790/829 15 Cucumber_mosaic_virus R-HSA-73887 Death Receptor Signalling 30/1181 141/10654 3.0975160108434987e-4 8.893094610317647e-4 3.8433099348641645e-4 9181/7124/7186/5584/7531/7375/835/8878/841/7316/5970/5664/329/843/836/11108/10454/3066/3065/7189/6233/7311/26574/8772/8874/5599/1540/5663/7314/5879 30 Cucumber_mosaic_virus R-HSA-74158 RNA Polymerase III Transcription 13/1181 41/10654 3.2017064241826907e-4 9.150823090738365e-4 3.9546919084854955e-4 5434/5440/5451/6617/5441/5435/5437/10302/6621/6908/7702/6619/6618 13 Cucumber_mosaic_virus R-HSA-749476 RNA Polymerase III Abortive And Retractive Initiation 13/1181 41/10654 3.2017064241826907e-4 9.150823090738365e-4 3.9546919084854955e-4 5434/5440/5451/6617/5441/5435/5437/10302/6621/6908/7702/6619/6618 13 Cucumber_mosaic_virus R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 12/1181 36/10654 3.2154495919478544e-4 9.169450634116465e-4 3.9627421346063443e-4 25/71/10093/5594/10094/10152/2885/10096/23191/60/5879/5595 12 Cucumber_mosaic_virus R-HSA-5675482 Regulation of necroptotic cell death 8/1181 18/10654 3.507306605848577e-4 9.97930960273956e-4 4.312737176415173e-4 7186/841/7316/329/6233/7311/8772/7314 8 Cucumber_mosaic_virus R-HSA-2559583 Cellular Senescence 38/1181 195/10654 3.5410971558536735e-4 0.0010052913402188615 4.3445463751319065e-4 1017/7014/1019/5601/5606/5594/7295/5925/7013/1051/472/192670/7316/890/6774/5970/1026/6667/1432/4683/5602/1021/6195/192669/7157/4001/5609/6233/7311/8726/6197/5599/5600/26523/7314/23523/5595/4193 38 Cucumber_mosaic_virus R-HSA-195721 Signaling by WNT 57/1181 331/10654 4.4450693690979877e-4 0.001259105586916372 5.441450050047113e-4 8454/27161/8945/815/5684/857/7015/5579/1499/207/1452/5578/5582/6500/79577/1460/55737/5705/192670/7534/8452/5528/7316/10213/9978/1457/5216/4609/5519/2932/5701/1387/4919/324/2033/2783/5710/192669/3065/208/5704/6233/7311/5518/1213/8607/808/3845/26523/801/5693/7314/5879/805/123169/5515/5516 57 Cucumber_mosaic_virus R-HSA-373753 Nephrin family interactions 9/1181 23/10654 4.7151936560961756e-4 0.0013296846110191214 5.746469929417795e-4 5295/8573/6711/5290/81/2534/87/6709/8826 9 Cucumber_mosaic_virus R-HSA-9617324 Negative regulation of NMDA receptor-mediated neuronal transmission 9/1181 23/10654 4.7151936560961756e-4 0.0013296846110191214 5.746469929417795e-4 818/815/817/816/808/801/814/4747/805 9 Cucumber_mosaic_virus R-HSA-112316 Neuronal System 68/1181 413/10654 4.882182321837248e-4 0.0013737226976522103 5.936788399293281e-4 818/5170/5563/84617/815/3838/8573/8496/28964/1312/5579/5567/817/4646/5578/5594/5568/51422/5582/7277/114/53632/10381/108/7278/112714/107/3359/10645/6714/5566/84254/5571/26037/7846/590/113457/91683/10376/6195/2783/4137/18/816/1385/5562/10383/84790/8874/808/3751/6197/3845/115/3265/3312/5564/801/5565/814/109/6506/4747/6812/5879/5595/4193/805 68 Cucumber_mosaic_virus R-HSA-2025928 Calcineurin activates NFAT 6/1181 11/10654 5.16844500462066e-4 0.0014383238401016706 6.215973793645808e-4 4775/2280/5478/808/801/805 6 Cucumber_mosaic_virus R-HSA-2514853 Condensation of Prometaphase Chromosomes 6/1181 11/10654 5.16844500462066e-4 0.0014383238401016706 6.215973793645808e-4 1460/10051/891/1457/983/10592 6 Cucumber_mosaic_virus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 6/1181 11/10654 5.16844500462066e-4 0.0014383238401016706 6.215973793645808e-4 7316/10454/7189/6233/7311/7314 6 Cucumber_mosaic_virus R-HSA-9614399 Regulation of localization of FOXO transcription factors 6/1181 11/10654 5.16844500462066e-4 0.0014383238401016706 6.215973793645808e-4 2309/207/10971/7534/208/7529 6 Cucumber_mosaic_virus R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 6/1181 11/10654 5.16844500462066e-4 0.0014383238401016706 6.215973793645808e-4 7316/10454/7189/6233/7311/7314 6 Cucumber_mosaic_virus R-HSA-8876725 Protein methylation 8/1181 19/10654 5.472971277571489e-4 0.0015197375385641618 6.567817656604275e-4 1938/1915/7415/808/3312/801/6187/805 8 Cucumber_mosaic_virus R-HSA-5696394 DNA Damage Recognition in GG-NER 12/1181 38/10654 5.638429407234705e-4 0.0015588598949413596 6.736891918746202e-4 86/8450/7316/9978/142/10987/6233/7311/60/8607/7314/8451 12 Cucumber_mosaic_virus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 12/1181 38/10654 5.638429407234705e-4 0.0015588598949413596 6.736891918746202e-4 4605/4869/4839/51741/348/1026/2099/4609/3329/1387/2033/1956 12 Cucumber_mosaic_virus R-HSA-1592230 Mitochondrial biogenesis 22/1181 95/10654 5.697167155218363e-4 0.0015716750260808918 6.792274800615028e-4 5563/3418/51422/53632/3313/4209/5469/10989/1432/5571/4208/1387/1385/1386/808/5600/5564/6300/801/5565/814/805 22 Cucumber_mosaic_virus R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 7/1181 15/10654 5.8142948558458e-4 0.0016005076295159046 6.916880054562534e-4 7316/9146/30011/6233/2885/7311/7314 7 Cucumber_mosaic_virus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 16/1181 60/10654 6.179972873236783e-4 0.0016974860554410125 7.33598967180762e-4 8454/8945/5684/6500/5705/7316/10213/5970/5701/5710/9040/5704/6233/7311/5693/7314 16 Cucumber_mosaic_virus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 17/1181 66/10654 6.535458467510899e-4 0.001791252007617998 7.74121600903303e-4 5684/112399/3091/5705/7316/10213/9978/8994/7322/5701/5710/8453/5704/6233/7311/5693/7314 17 Cucumber_mosaic_virus R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 28/1181 134/10654 6.567828335581522e-4 0.0017962444305717566 7.762791657980882e-4 351/1072/5579/5340/2316/5578/5582/7277/29106/5216/710/6647/1191/23052/3920/226/81/3309/9948/2335/87/5478/2/8407/7040/808/801/805 28 Cucumber_mosaic_virus R-HSA-141424 Amplification of signal from the kinetochores 22/1181 96/10654 6.633401322946964e-4 0.0018063919053261151 7.806645785532794e-4 4928/5903/54908/55143/1058/348995/79023/57122/6232/1780/5528/5501/23279/79902/5519/22919/5518/9793/10726/55746/5515/5516 22 Cucumber_mosaic_virus R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 22/1181 96/10654 6.633401322946964e-4 0.0018063919053261151 7.806645785532794e-4 4928/5903/54908/55143/1058/348995/79023/57122/6232/1780/5528/5501/23279/79902/5519/22919/5518/9793/10726/55746/5515/5516 22 Cucumber_mosaic_virus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 9/1181 24/10654 6.808844566959984e-4 0.00184230783698768 7.961862909631135e-4 5606/7316/1432/10454/7189/6233/7311/5600/7314 9 Cucumber_mosaic_virus R-HSA-8940973 RUNX2 regulates osteoblast differentiation 9/1181 24/10654 6.808844566959984e-4 0.00184230783698768 7.961862909631135e-4 25/5594/5925/10013/10413/6714/7525/367/5595 9 Cucumber_mosaic_virus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 9/1181 24/10654 6.808844566959984e-4 0.00184230783698768 7.961862909631135e-4 2309/207/5594/6722/595/208/1385/1956/5595 9 Cucumber_mosaic_virus R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 15/1181 55/10654 7.012212148430952e-4 0.0018892775406282119 8.164850886875686e-4 8454/8945/26271/5684/6500/5705/7316/10213/5701/5710/5704/6233/7311/5693/7314 15 Cucumber_mosaic_virus R-HSA-8941858 Regulation of RUNX3 expression and activity 15/1181 55/10654 7.012212148430952e-4 0.0018892775406282119 8.164850886875686e-4 5684/5705/7316/10213/6714/5701/2033/5710/5704/6233/7311/7040/5693/7314/4193 15 Cucumber_mosaic_virus R-HSA-186763 Downstream signal transduction 10/1181 29/10654 7.454927771474681e-4 0.0019958445869201202 8.625399442456826e-4 5295/5290/5335/6774/6772/6714/2885/3845/3265/5156 10 Cucumber_mosaic_virus R-HSA-5205647 Mitophagy 10/1181 29/10654 7.454927771474681e-4 0.0019958445869201202 8.625399442456826e-4 8878/1460/9474/7316/1457/6714/8408/6233/7311/7314 10 Cucumber_mosaic_virus R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 10/1181 29/10654 7.454927771474681e-4 0.0019958445869201202 8.625399442456826e-4 5105/2309/4287/847/4089/4088/3630/3066/3065/4087 10 Cucumber_mosaic_virus R-HSA-1169091 Activation of NF-kappaB in B cells 17/1181 67/10654 7.869795149265727e-4 0.0020936624831065427 9.048136980618876e-4 8454/8945/5684/5579/6500/5705/7316/10213/5970/8915/5701/5710/5704/6233/7311/5693/7314 17 Cucumber_mosaic_virus R-HSA-5685942 HDR through Homologous Recombination (HRR) 17/1181 67/10654 7.869795149265727e-4 0.0020936624831065427 9.048136980618876e-4 675/54107/545/472/580/7316/5111/7517/4683/84126/1111/5984/6233/672/7311/5983/7314 17 Cucumber_mosaic_virus R-HSA-73856 RNA Polymerase II Transcription Termination 17/1181 67/10654 7.869795149265727e-4 0.0020936624831065427 9.048136980618876e-4 6635/6432/8683/7884/80145/79869/51585/6428/8106/10212/4686/10189/9939/9775/6427/22916/1479 17 Cucumber_mosaic_virus R-HSA-5213460 RIPK1-mediated regulated necrosis 8/1181 20/10654 8.24199857229803e-4 0.0021835273879428395 9.436504243857319e-4 7186/841/7316/329/6233/7311/8772/7314 8 Cucumber_mosaic_virus R-HSA-5218859 Regulated Necrosis 8/1181 20/10654 8.24199857229803e-4 0.0021835273879428395 9.436504243857319e-4 7186/841/7316/329/6233/7311/8772/7314 8 Cucumber_mosaic_virus R-HSA-2132295 MHC class II antigen presentation 26/1181 123/10654 8.410173632801054e-4 0.0022234396541717786 9.608992242739801e-4 84617/1785/830/3123/7277/10381/7278/112714/1780/3122/1509/22872/1639/832/5641/7846/113457/89953/10376/3799/1213/10383/84790/9493/7879/829 26 Cucumber_mosaic_virus R-HSA-8878171 Transcriptional regulation by RUNX1 43/1181 239/10654 8.772573125393449e-4 0.0023144272964915357 0.0010002211616872716 27161/25/894/5684/902/5579/1460/3958/6598/5705/192670/86/7316/10213/7082/1457/4331/10413/6714/2099/5701/1387/2033/1021/6605/595/6886/4602/5710/192669/3065/861/896/5371/23067/5704/6233/7311/26523/1022/5693/4297/7314 43 Cucumber_mosaic_virus R-HSA-6790901 rRNA modification in the nucleus and cytosol 16/1181 62/10654 9.12432867291993e-4 0.0024022350800695833 0.001038168866257105 2091/6203/6194/54433/10528/4839/55272/9790/51077/10171/5822/27341/6201/6187/6208/22984 16 Cucumber_mosaic_virus R-HSA-110312 Translesion synthesis by REV1 7/1181 16/10654 9.353001435753924e-4 0.0024167323884267495 0.0010444341374230323 7316/5111/5984/6233/7311/5983/7314 7 Cucumber_mosaic_virus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 7/1181 16/10654 9.353001435753924e-4 0.0024167323884267495 0.0010444341374230323 5590/7316/2280/6233/7311/7040/7314 7 Cucumber_mosaic_virus R-HSA-392517 Rap1 signalling 7/1181 16/10654 9.353001435753924e-4 0.0024167323884267495 0.0010444341374230323 5567/5568/7534/5566/5894/5906/7529 7 Cucumber_mosaic_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 7/1181 16/10654 9.353001435753924e-4 0.0024167323884267495 0.0010444341374230323 8454/8945/6500/7316/6233/7311/7314 7 Cucumber_mosaic_virus R-HSA-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation 6/1181 12/10654 9.369837156075341e-4 0.0024167323884267495 0.0010444341374230323 207/3320/4846/808/801/805 6 Cucumber_mosaic_virus R-HSA-170968 Frs2-mediated activation 6/1181 12/10654 9.369837156075341e-4 0.0024167323884267495 0.0010444341374230323 5594/5605/4914/5906/7529/5595 6 Cucumber_mosaic_virus R-HSA-190873 Gap junction degradation 6/1181 12/10654 9.369837156075341e-4 0.0024167323884267495 0.0010444341374230323 71/4646/1785/8218/1213/60 6 Cucumber_mosaic_virus R-HSA-430116 GP1b-IX-V activation signalling 6/1181 12/10654 9.369837156075341e-4 0.0024167323884267495 0.0010444341374230323 5295/2316/7534/6714/5894/2814 6 Cucumber_mosaic_virus R-HSA-5689877 Josephin domain DUBs 6/1181 12/10654 9.369837156075341e-4 0.0024167323884267495 0.0010444341374230323 4287/7316/7415/6233/7311/7314 6 Cucumber_mosaic_virus R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 6/1181 12/10654 9.369837156075341e-4 0.0024167323884267495 0.0010444341374230323 834/835/472/843/7157/839 6 Cucumber_mosaic_virus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 20/1181 86/10654 9.419450029204537e-4 0.0024189880258511432 0.0010454089514897315 8454/1017/8945/26271/5684/6500/5705/7316/10213/891/890/983/5701/6502/5710/5704/6233/7311/5693/7314 20 Cucumber_mosaic_virus R-HSA-453276 Regulation of mitotic cell cycle 20/1181 86/10654 9.419450029204537e-4 0.0024189880258511432 0.0010454089514897315 8454/1017/8945/26271/5684/6500/5705/7316/10213/891/890/983/5701/6502/5710/5704/6233/7311/5693/7314 20 Cucumber_mosaic_virus R-HSA-445355 Smooth Muscle Contraction 12/1181 40/10654 9.435768895164034e-4 0.0024189880258511432 0.0010454089514897315 10627/7168/301/7171/4637/302/7169/103910/808/801/7170/805 12 Cucumber_mosaic_virus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 19/1181 80/10654 9.548067254006711e-4 0.0024428422067206686 0.0010557179625079577 8454/1017/8945/26271/5684/6500/5705/7316/10213/891/890/983/5701/5710/5704/6233/7311/5693/7314 19 Cucumber_mosaic_virus R-HSA-9620244 Long-term potentiation 9/1181 25/10654 9.603070857874718e-4 0.002451971210994571 0.0010596632250244051 818/815/817/6714/816/808/801/4747/805 9 Cucumber_mosaic_virus R-HSA-9615710 Microautophagy 11/1181 35/10654 9.953125131187618e-4 0.002536248150899014 0.0010960850123332803 25978/1080/10013/7316/51271/6233/7311/7431/3312/11315/7314 11 Cucumber_mosaic_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 10/1181 30/10654 0.0010084949907763156 0.0025595602865902886 0.0011061597688304431 7124/7186/7375/7316/329/10454/6233/7311/1540/7314 10 Cucumber_mosaic_virus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 10/1181 30/10654 0.0010084949907763156 0.0025595602865902886 0.0011061597688304431 7319/7316/7322/7347/6233/7311/55284/27338/997/7314 10 Cucumber_mosaic_virus R-HSA-69541 Stabilization of p53 15/1181 57/10654 0.0010512584235036345 0.002662768342167889 0.0011507629764584382 5684/11200/472/5705/7316/10213/5701/5710/7157/5704/6233/7311/5693/7314/4193 15 Cucumber_mosaic_virus R-HSA-5693538 Homology Directed Repair 28/1181 138/10654 0.001064146893439109 0.0026900446370004567 0.0011625509152480096 1017/25/2237/5893/675/63967/54107/545/472/6613/580/7316/890/5111/7517/9656/4683/84126/142/1111/5984/6233/672/7158/7311/6047/5983/7314 28 Cucumber_mosaic_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 16/1181 63/10654 0.0010995642928182578 0.0027740498759172352 0.0011988552821142876 5434/5440/1499/5441/5591/5435/7316/5970/1387/5437/2033/1660/6233/7311/2547/7314 16 Cucumber_mosaic_virus R-HSA-69239 Synthesis of DNA 25/1181 119/10654 0.0011511226891147682 0.002898362485092541 0.0012525792001436805 8454/1017/2237/5684/6500/54107/5705/7316/10213/5422/9978/4174/890/5111/4171/5701/6502/5710/5984/5704/6233/7311/5983/5693/7314 25 Cucumber_mosaic_virus R-HSA-180534 Vpu mediated degradation of CD4 14/1181 52/10654 0.0012014999384378762 0.0030132478693234484 0.0013022289742586509 8945/5684/6500/5705/7316/10213/920/5701/5710/5704/6233/7311/5693/7314 14 Cucumber_mosaic_virus R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 14/1181 52/10654 0.0012014999384378762 0.0030132478693234484 0.0013022289742586509 1019/5684/5705/7316/10213/2932/5701/595/5710/5704/6233/7311/5693/7314 14 Cucumber_mosaic_virus R-HSA-3858494 Beta-catenin independent WNT signaling 29/1181 146/10654 0.0012415277349360119 0.0031074924963191307 0.0013429584758676678 27161/815/5684/5579/1499/5578/5582/5705/192670/7316/10213/5216/5701/4919/2783/5710/192669/5704/6233/7311/1213/808/3845/26523/801/5693/7314/5879/805 29 Cucumber_mosaic_virus R-HSA-72187 mRNA 3'-end processing 15/1181 58/10654 0.0012753558909877599 0.003185879184376904 0.0013768346854633711 6432/8683/80145/79869/51585/6428/8106/10212/4686/10189/9939/9775/6427/22916/1479 15 Cucumber_mosaic_virus R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 10/1181 31/10654 0.0013428000582022862 0.0033412024977621593 0.0014439604341040064 857/1499/1452/5528/5519/2932/324/5518/5515/5516 10 Cucumber_mosaic_virus R-HSA-5339562 Uptake and actions of bacterial toxins 10/1181 31/10654 0.0013428000582022862 0.0033412024977621593 0.0014439604341040064 5606/1938/10015/5605/3320/5609/3326/808/801/805 10 Cucumber_mosaic_virus R-HSA-6807878 COPI-mediated anterograde transport 22/1181 101/10654 0.0013585782861777439 0.003373847055106765 0.0014580683635773087 84617/6711/830/7277/10381/7278/112714/1780/1315/1639/832/7846/113457/10376/3630/9276/6709/10383/84790/378/829/372 22 Cucumber_mosaic_virus R-HSA-69306 DNA Replication 26/1181 127/10654 0.0013785922344018585 0.0034168623934686688 0.0014766582116023197 8454/1017/2237/5684/8317/6500/54107/5705/7316/10213/5422/9978/4174/890/5111/4171/5701/6502/5710/5984/5704/6233/7311/5983/5693/7314 26 Cucumber_mosaic_virus R-HSA-432142 Platelet sensitization by LDL 7/1181 17/10654 0.0014390086462601093 0.003538957310279222 0.001529423714201381 2268/5528/5519/1432/5518/5515/5516 7 Cucumber_mosaic_virus R-HSA-450385 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA 7/1181 17/10654 0.0014390086462601093 0.003538957310279222 0.001529423714201381 207/51010/54464/56915/54512/167227/7529 7 Cucumber_mosaic_virus R-HSA-5655862 Translesion synthesis by POLK 7/1181 17/10654 0.0014390086462601093 0.003538957310279222 0.001529423714201381 7316/5111/5984/6233/7311/5983/7314 7 Cucumber_mosaic_virus R-HSA-5656121 Translesion synthesis by POLI 7/1181 17/10654 0.0014390086462601093 0.003538957310279222 0.001529423714201381 7316/5111/5984/6233/7311/5983/7314 7 Cucumber_mosaic_virus R-HSA-983231 Factors involved in megakaryocyte development and platelet production 32/1181 168/10654 0.001485669494383437 0.003646643304395709 0.0015759621430800584 1017/84617/25/30846/5567/5568/830/7277/10381/7278/112714/832/5566/80005/2627/7846/113457/89953/10376/4602/3066/3065/7157/3799/10383/60/84790/9493/1020/3660/829/5879 32 Cucumber_mosaic_virus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 15/1181 59/10654 0.0015382506987749347 0.0037684172524042317 0.0016285889332691343 8454/8945/5684/6500/5705/7316/10213/5701/5710/9040/5704/6233/7311/5693/7314 15 Cucumber_mosaic_virus R-HSA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 6/1181 13/10654 0.001577699684643775 0.003842804030351152 0.0016607365101513419 5925/5422/5519/5518/5515/5516 6 Cucumber_mosaic_virus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 6/1181 13/10654 0.001577699684643775 0.003842804030351152 0.0016607365101513419 207/7316/208/6233/7311/7314 6 Cucumber_mosaic_virus R-HSA-5357786 TNFR1-induced proapoptotic signaling 6/1181 13/10654 0.001577699684643775 0.003842804030351152 0.0016607365101513419 7124/7186/7375/841/8772/1540 6 Cucumber_mosaic_virus R-HSA-113510 E2F mediated regulation of DNA replication 8/1181 22/10654 0.001709015353232925 0.0041546752552731455 0.0017955172394320507 5925/5422/891/983/5519/5518/5515/5516 8 Cucumber_mosaic_virus R-HSA-74751 Insulin receptor signalling cascade 14/1181 54/10654 0.0017850291535638958 0.004322904572275923 0.0018682205484266568 5295/5170/5290/3667/5594/2260/5289/2264/3630/208/2885/3845/3265/5595 14 Cucumber_mosaic_virus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 14/1181 54/10654 0.0017850291535638958 0.004322904572275923 0.0018682205484266568 8454/5684/6500/5705/7316/10213/9978/5701/5710/5704/6233/7311/5693/7314 14 Cucumber_mosaic_virus R-HSA-1538133 G0 and Early G1 9/1181 27/10654 0.0017957754514772379 0.004340645805570695 0.0018758877397887538 1017/4605/890/983/5111/4609/1874/3065/1859 9 Cucumber_mosaic_virus R-HSA-193704 p75 NTR receptor-mediated signalling 21/1181 97/10654 0.001873161441998628 0.004519091007407336 0.0019530060261782774 9181/5584/7531/835/8878/7316/5970/5664/836/11108/3066/3065/7189/6233/7311/26574/8874/5599/5663/7314/5879 21 Cucumber_mosaic_virus R-HSA-75893 TNF signaling 12/1181 43/10654 0.0018934646293397948 0.004559405340858064 0.0019704285866094734 7124/7186/7375/841/7316/329/10454/6233/7311/8772/1540/7314 12 Cucumber_mosaic_virus R-HSA-73854 RNA Polymerase I Promoter Clearance 23/1181 110/10654 0.001901246906421503 0.004569474098956226 0.001974779980553435 5434/5440/902/25885/404672/5441/11335/5435/4331/1108/2966/5437/2965/2068/3066/3065/2071/1107/2968/2967/6908/1022/5595 23 Cucumber_mosaic_virus R-HSA-5689880 Ub-specific processing proteases 39/1181 220/10654 0.0019717469437806057 0.0047299562791258765 0.0020441352257679745 5684/7186/7375/55611/63967/4086/1080/3091/5705/7316/10213/890/7417/8678/4609/4089/5701/329/6502/4088/9146/5728/5710/10454/7157/9958/4087/63891/7189/5704/6233/7311/367/23770/8607/1540/5693/7314/4193 39 Dengue_virus_type_1 R-HSA-909733 Interferon alpha/beta signaling 32/106 69/10654 1.7574415942985964e-47 8.910228883093883e-45 5.623813101755508e-45 3449/3440/3455/3448/10379/9021/3443/3660/3665/3434/3456/3444/3446/3452/6773/6772/3454/7297/8651/3663/5781/5777/3659/3662/4599/3445/3664/3451/3661/3441/5770/3716 32 Dengue_virus_type_1 R-HSA-912694 Regulation of IFNA signaling 22/106 26/10654 1.2720732510224532e-41 3.224705691341919e-39 2.035317201635925e-39 3449/3440/3455/3448/9021/3443/3456/3444/3446/3452/6773/6772/3454/7297/8651/5781/5777/3445/3451/3441/5770/3716 22 Dengue_virus_type_1 R-HSA-913531 Interferon Signaling 37/106 199/10654 5.65871817941487e-38 9.56323372321113e-36 6.035966058042528e-36 3449/3717/3440/3455/3448/10379/9021/3459/3443/3660/3665/3434/3456/3444/3446/3452/6773/6772/3458/3460/3454/7297/8651/3663/5781/5777/3659/3662/4599/3445/3664/3451/3661/3441/5770/3716/23586 37 Dengue_virus_type_1 R-HSA-449147 Signaling by Interleukins 46/106 461/10654 4.754089226819692e-35 6.0258080949939596e-33 3.8032713814557536e-33 3717/59307/51135/3605/3557/7124/11213/3559/3627/3586/3654/2353/9021/3576/29110/282618/3563/4615/7189/53832/3554/3553/163702/6773/6772/3552/6352/3458/3320/7297/8651/3588/5781/3725/5777/4790/3662/3569/54472/5970/6597/3146/3656/3556/3716/1386 46 Dengue_virus_type_1 R-HSA-933541 TRAF6 mediated IRF7 activation 20/106 29/10654 1.2673785921280584e-34 1.2851218924178512e-32 8.111222989619573e-33 3449/64135/3440/3448/3443/3665/29110/7189/3456/3444/3446/3452/57506/1387/3445/2033/3451/3661/3441/23586 20 Dengue_virus_type_1 R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 23/106 78/10654 1.58046634827272e-28 1.3354940642904485e-26 8.429153857454507e-27 3449/64135/3440/3448/3443/3665/29110/7189/3456/3444/3446/3452/57506/4790/1387/3445/2033/5970/3146/3451/3661/3441/23586 23 Dengue_virus_type_1 R-HSA-168898 Toll-like Receptor Cascades 24/106 155/10654 1.8524810977659753e-22 1.3417255950962136e-20 8.468485018358744e-21 54106/7097/59307/7099/51135/11213/3654/2353/3665/29110/4615/7189/929/7098/8651/5781/3725/51284/4790/5970/3146/3661/3656/1386 24 Dengue_virus_type_1 R-HSA-877312 Regulation of IFNG signaling 11/106 14/10654 1.9732920662134752e-20 1.207400383796255e-18 7.620673033822517e-19 3717/9021/3459/6772/3458/3460/8651/5781/5777/5770/3716 11 Dengue_virus_type_1 R-HSA-877300 Interferon gamma signaling 19/106 92/10654 2.1433142907625828e-20 1.207400383796255e-18 7.620673033822517e-19 3717/10379/9021/3459/3660/3665/6772/3458/3460/8651/3663/5781/5777/3659/3662/3664/3661/5770/3716 19 Dengue_virus_type_1 R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 21/106 129/10654 3.5147192561890846e-20 1.781962662887866e-18 1.124710161980507e-18 7097/59307/7099/51135/11213/3654/2353/3665/29110/4615/7189/929/8651/5781/3725/4790/5970/3146/3661/3656/1386 21 Dengue_virus_type_1 R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 17/106 95/10654 3.303959813687028e-17 1.3959230212827693e-15 8.810559503165408e-16 7097/59307/7099/51135/11213/3654/2353/4615/7189/929/8651/3725/4790/5970/3146/3656/1386 17 Dengue_virus_type_1 R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 17/106 95/10654 3.303959813687028e-17 1.3959230212827693e-15 8.810559503165408e-16 7097/59307/7099/51135/11213/3654/2353/4615/7189/929/8651/3725/4790/5970/3146/3656/1386 17 Dengue_virus_type_1 R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 17/106 98/10654 5.75059687090067e-17 2.0825375811047427e-15 1.314422141920153e-15 7097/59307/7099/51135/11213/3654/2353/4615/7189/929/8651/3725/4790/5970/3146/3656/1386 17 Dengue_virus_type_1 R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 17/106 98/10654 5.75059687090067e-17 2.0825375811047427e-15 1.314422141920153e-15 7097/59307/7099/51135/11213/3654/2353/4615/7189/929/8651/3725/4790/5970/3146/3656/1386 17 Dengue_virus_type_1 R-HSA-446652 Interleukin-1 family signaling 19/106 140/10654 8.786919653367847e-17 2.969978842838332e-15 1.8745428593851407e-15 59307/51135/3557/11213/3654/29110/4615/7189/3554/3553/3552/5781/5777/4790/54472/5970/3146/3656/3556 19 Dengue_virus_type_1 R-HSA-6783783 Interleukin-10 signaling 13/106 47/10654 4.670556516472278e-16 1.479982596157153e-14 9.341113032944557e-15 3557/7124/3627/3586/3576/3554/3553/3552/6352/7297/3588/3569/3716 13 Dengue_virus_type_1 R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 16/106 93/10654 5.818395242368237e-16 1.6388479932670535e-14 1.03438137642102e-14 54106/7099/51135/3654/2353/3665/4615/7189/929/3725/51284/4790/5970/3146/3656/1386 16 Dengue_virus_type_1 R-HSA-975155 MyD88 dependent cascade initiated on endosome 16/106 93/10654 5.818395242368237e-16 1.6388479932670535e-14 1.03438137642102e-14 54106/7099/51135/3654/2353/3665/4615/7189/929/3725/51284/4790/5970/3146/3656/1386 16 Dengue_virus_type_1 R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 16/106 97/10654 1.1734037086272284e-15 3.1311351593368675e-14 1.976258877687964e-14 54106/7099/51135/3654/2353/3665/4615/7189/929/3725/51284/4790/5970/3146/3656/1386 16 Dengue_virus_type_1 R-HSA-918233 TRAF3-dependent IRF activation pathway 9/106 14/10654 1.2989261473766412e-15 3.292777783599786e-14 2.0782818358026256e-14 64135/3665/29110/3456/57506/1387/2033/3661/23586 9 Dengue_virus_type_1 R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 16/106 108/10654 6.8938557814243345e-15 1.664373752943875e-13 1.0504923095503749e-13 3717/3605/7124/3586/2353/9021/3576/3553/6772/3552/3320/7297/8651/3662/3569/3716 16 Dengue_virus_type_1 R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 15/106 92/10654 1.1653134545012053e-14 2.685517824691414e-13 1.6950013883653895e-13 54106/7099/51135/3654/2353/4615/7189/929/3725/51284/4790/5970/3146/3656/1386 15 Dengue_virus_type_1 R-HSA-8854691 Interleukin-20 family signaling 10/106 25/10654 1.779801307219309e-14 3.9233011424356074e-13 2.476245297000778e-13 3717/282618/53832/163702/6773/6772/7297/3588/5781/3716 10 Dengue_virus_type_1 R-HSA-166166 MyD88-independent TLR4 cascade 15/106 99/10654 3.6193294066202875e-14 7.340000036625943e-13 4.632741640473968e-13 7099/3654/2353/3665/29110/7189/929/5781/3725/4790/5970/3146/3661/3656/1386 15 Dengue_virus_type_1 R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 15/106 99/10654 3.6193294066202875e-14 7.340000036625943e-13 4.632741640473968e-13 7099/3654/2353/3665/29110/7189/929/5781/3725/4790/5970/3146/3661/3656/1386 15 Dengue_virus_type_1 R-HSA-9020702 Interleukin-1 signaling 15/106 103/10654 6.64377024230364e-14 1.2955351972492097e-12 8.176947990527556e-13 51135/3557/11213/3654/4615/7189/3554/3553/3552/4790/54472/5970/3146/3656/3556 15 Dengue_virus_type_1 R-HSA-1059683 Interleukin-6 signaling 7/106 11/10654 2.5227715417303493e-12 4.737204339471434e-11 2.989951456865599e-11 3717/9021/6772/7297/5781/3569/3716 7 Dengue_virus_type_1 R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 13/106 94/10654 6.812061115392862e-12 1.2334696376800647e-10 7.785212703306129e-11 3654/2353/3665/29110/7189/7098/3725/4790/5970/3146/3661/3656/1386 13 Dengue_virus_type_1 R-HSA-5260271 Diseases of Immune System 8/106 24/10654 4.73635909568104e-11 7.787012212413498e-10 4.914879502903983e-10 7097/7099/51135/4615/929/7098/4790/5970 8 Dengue_virus_type_1 R-HSA-5602358 Diseases associated with the TLR signaling cascade 8/106 24/10654 4.73635909568104e-11 7.787012212413498e-10 4.914879502903983e-10 7097/7099/51135/4615/929/7098/4790/5970 8 Dengue_virus_type_1 R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 7/106 15/10654 4.7612895184382334e-11 7.787012212413498e-10 4.914879502903983e-10 54106/51135/3654/3665/4615/7189/51284 7 Dengue_virus_type_1 R-HSA-983231 Factors involved in megakaryocyte development and platelet production 15/106 168/10654 9.251550965490115e-11 1.4657926060948402e-9 9.251550965490116e-10 3449/3717/3440/60/3448/3443/3660/3456/3444/3446/3452/3659/3445/3451/3441 15 Dengue_virus_type_1 R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 11/106 85/10654 6.450431278633407e-10 9.343910452191821e-9 5.897537169036258e-9 51135/3654/2353/4615/7189/3725/4790/5970/3146/3656/1386 11 Dengue_virus_type_1 R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 11/106 85/10654 6.450431278633407e-10 9.343910452191821e-9 5.897537169036258e-9 51135/3654/2353/4615/7189/3725/4790/5970/3146/3656/1386 11 Dengue_virus_type_1 R-HSA-975871 MyD88 cascade initiated on plasma membrane 11/106 85/10654 6.450431278633407e-10 9.343910452191821e-9 5.897537169036258e-9 51135/3654/2353/4615/7189/3725/4790/5970/3146/3656/1386 11 Dengue_virus_type_1 R-HSA-6783589 Interleukin-6 family signaling 7/106 24/10654 2.379413669458972e-9 3.260439811934321e-8 2.057871281694246e-8 3717/9021/6772/7297/5781/3569/3716 7 Dengue_virus_type_1 R-HSA-933542 TRAF6 mediated NF-kB activation 7/106 24/10654 2.379413669458972e-9 3.260439811934321e-8 2.057871281694246e-8 64135/7189/57506/4790/5970/3146/23586 7 Dengue_virus_type_1 R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 8/106 38/10654 2.8072866695909013e-9 3.7455114249541766e-8 2.3640308796554956e-8 6599/6601/8289/2033/6598/6605/6597/6602 8 Dengue_virus_type_1 R-HSA-193639 p75NTR signals via NF-kB 6/106 16/10654 6.212399252262004e-9 8.076119027940605e-8 5.097353232625235e-8 3654/4615/7189/4804/4790/5970 6 Dengue_virus_type_1 R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 9/106 63/10654 1.025740612339184e-8 1.3001262261399157e-7 8.205924898713472e-8 3665/29110/4615/7098/4790/1387/2033/5970/3661 9 Dengue_virus_type_1 R-HSA-8878171 Transcriptional regulation by RUNX1 15/106 239/10654 1.2490645939752686e-8 1.544574997915759e-7 9.748796831026487e-8 6599/6601/8861/3559/9021/8850/8289/3458/5781/1387/2033/6598/6605/6597/6602 15 Dengue_virus_type_1 R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 6/106 18/10654 1.4170759952828179e-8 1.7106131657342588e-7 1.0796769487869089e-7 7099/3665/29110/929/5781/3661 6 Dengue_virus_type_1 R-HSA-110056 MAPK3 (ERK1) activation 5/106 10/10654 2.1477557826350696e-8 2.5323539111534425e-7 1.5983298847516797e-7 3717/7297/5781/3569/3716 5 Dengue_virus_type_1 R-HSA-5603041 IRAK4 deficiency (TLR2/4) 5/106 11/10654 3.906454026998454e-8 4.5013004356550367e-7 2.8410574741806936e-7 7097/7099/51135/4615/929 5 Dengue_virus_type_1 R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 6/106 21/10654 4.043106777741517e-8 4.555233636255443e-7 2.875098153060634e-7 29110/4615/7098/4790/5970/3661 6 Dengue_virus_type_1 R-HSA-3247509 Chromatin modifying enzymes 15/106 274/10654 7.731519772862207e-8 8.340171329449231e-7 5.264013462374268e-7 3717/6599/6601/60/8850/8289/4790/1387/2033/5970/6598/6605/6597/6602/1386 15 Dengue_virus_type_1 R-HSA-4839726 Chromatin organization 15/106 274/10654 7.731519772862207e-8 8.340171329449231e-7 5.264013462374268e-7 3717/6599/6601/60/8850/8289/4790/1387/2033/5970/6598/6605/6597/6602/1386 15 Dengue_virus_type_1 R-HSA-982772 Growth hormone receptor signaling 6/106 24/10654 9.78859334677603e-8 1.0339201722532182e-6 6.525728897850687e-7 3717/9021/6772/8651/5777/5770 6 Dengue_virus_type_1 R-HSA-209560 NF-kB is activated and signals survival 5/106 13/10654 1.0711088656166803e-7 1.1082697854441977e-6 6.994996673415056e-7 3654/7189/4804/4790/5970 5 Dengue_virus_type_1 R-HSA-448424 Interleukin-17 signaling 8/106 72/10654 5.197737078374082e-7 5.270505397471319e-6 3.3265517301594125e-6 3605/3654/2353/7189/3725/4790/3656/1386 8 Dengue_virus_type_1 R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 6/106 33/10654 7.4908383316751e-7 7.4467745767828944e-6 4.700133855168691e-6 3654/7189/4790/5970/3146/3656 6 Dengue_virus_type_1 R-HSA-3214858 RMTs methylate histone arginines 8/106 79/10654 1.0697273835103878e-6 1.0429841989226281e-5 6.582937744679309e-6 3717/6599/6601/8289/6598/6605/6597/6602 8 Dengue_virus_type_1 R-HSA-5602498 MyD88 deficiency (TLR2/4) 4/106 10/10654 1.8567309022384807e-6 1.776155787613037e-5 1.1210450730496486e-5 7097/7099/4615/929 4 Dengue_virus_type_1 R-HSA-9018519 Estrogen-dependent gene expression 10/106 150/10654 2.273195350095612e-6 2.134277856478658e-5 1.347078725982585e-5 2962/2353/8850/3320/3725/2957/1387/5430/2033/1386 10 Dengue_virus_type_1 R-HSA-112409 RAF-independent MAPK1/3 activation 5/106 23/10654 2.5872019074185484e-6 2.3849297582930985e-5 1.5052811097707918e-5 3717/7297/5781/3569/3716 5 Dengue_virus_type_1 R-HSA-193692 Regulated proteolysis of p75NTR 4/106 11/10654 2.895397394791909e-6 2.575379787999119e-5 1.625486256725282e-5 7189/4804/4790/5970 4 Dengue_virus_type_1 R-HSA-9020956 Interleukin-27 signaling 4/106 11/10654 2.895397394791909e-6 2.575379787999119e-5 1.625486256725282e-5 3717/6772/7297/3716 4 Dengue_virus_type_1 R-HSA-450294 MAP kinase activation 7/106 64/10654 3.0821716106451393e-6 2.6942431148225612e-5 1.7005084748386976e-5 3654/2353/7189/3725/4790/3656/1386 7 Dengue_virus_type_1 R-HSA-449836 Other interleukin signaling 5/106 24/10654 3.2422850584582233e-6 2.7861669909124053e-5 1.7585274893332735e-5 282618/163702/7297/3588/3716 5 Dengue_virus_type_1 R-HSA-8984722 Interleukin-35 Signalling 4/106 12/10654 4.30987661209511e-6 3.572937157855684e-5 2.255108265313252e-5 3717/6772/7297/3716 4 Dengue_virus_type_1 R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 4/106 12/10654 4.30987661209511e-6 3.572937157855684e-5 2.255108265313252e-5 3665/29110/7098/3661 4 Dengue_virus_type_1 R-HSA-451927 Interleukin-2 family signaling 6/106 44/10654 4.369272264044426e-6 3.572937157855684e-5 2.255108265313252e-5 3717/3559/3563/6772/5777/3716 6 Dengue_virus_type_1 R-HSA-912526 Interleukin receptor SHC signaling 5/106 27/10654 6.013804016258539e-6 4.8396803749890146e-5 3.0546306114329084e-5 3717/3559/3563/5777/3716 5 Dengue_virus_type_1 R-HSA-209543 p75NTR recruits signalling complexes 4/106 13/10654 6.177772490109953e-6 4.893954144508978e-5 3.0888862450549765e-5 3654/4615/7189/4804 4 Dengue_virus_type_1 R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 6/106 48/10654 7.3548221188321364e-6 5.736761252689066e-5 3.620835504655821e-5 3717/3559/3563/5781/5777/3716 6 Dengue_virus_type_1 R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 4/106 16/10654 1.5367420091186213e-5 1.1804972706411227e-4 7.450870347241801e-5 7099/7189/929/3656 4 Dengue_virus_type_1 R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 5/106 34/10654 1.961227957654317e-5 1.4651984854343705e-4 9.247801091498985e-5 64135/29110/57506/3661/23586 5 Dengue_virus_type_1 R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 4/106 17/10654 1.994233988597015e-5 1.4651984854343705e-4 9.247801091498985e-5 4615/7098/4790/5970 4 Dengue_virus_type_1 R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 4/106 17/10654 1.994233988597015e-5 1.4651984854343705e-4 9.247801091498985e-5 7099/7189/929/3656 4 Dengue_virus_type_1 R-HSA-447115 Interleukin-12 family signaling 6/106 57/10654 2.022956488765403e-5 1.4651984854343705e-4 9.247801091498985e-5 3717/3586/6772/3458/7297/3716 6 Dengue_virus_type_1 R-HSA-5686938 Regulation of TLR by endogenous ligand 4/106 19/10654 3.1983399246876657e-5 2.28388498847415e-4 1.4415053181690888e-4 7097/7099/929/3146 4 Dengue_virus_type_1 R-HSA-5621575 CD209 (DC-SIGN) signaling 4/106 21/10654 4.86351310286388e-5 3.3778097851397084e-4 2.1319509492006048e-4 4790/1387/2033/5970 4 Dengue_virus_type_1 R-HSA-9008059 Interleukin-37 signaling 4/106 21/10654 4.86351310286388e-5 3.3778097851397084e-4 2.1319509492006048e-4 59307/29110/5781/5777 4 Dengue_virus_type_1 R-HSA-1433557 Signaling by SCF-KIT 5/106 43/10654 6.319339888081125e-5 4.3296017881853114e-4 2.7326875191702166e-4 3717/6772/8651/5781/5777 5 Dengue_virus_type_1 R-HSA-8939211 ESR-mediated signaling 10/106 223/10654 7.271628471820228e-5 4.915620846950474e-4 3.1025614813099637e-4 2962/2353/8850/3320/3725/2957/1387/5430/2033/1386 10 Dengue_virus_type_1 R-HSA-1169408 ISG15 antiviral mechanism 6/106 72/10654 7.720636181470404e-5 5.150477031586178e-4 3.2507941816717497e-4 3434/6772/4599/3661/3716/23586 6 Dengue_virus_type_1 R-HSA-167161 HIV Transcription Initiation 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 2962/2960/2959/2957/5430 5 Dengue_virus_type_1 R-HSA-167162 RNA Polymerase II HIV Promoter Escape 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 2962/2960/2959/2957/5430 5 Dengue_virus_type_1 R-HSA-73776 RNA Polymerase II Promoter Escape 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 2962/2960/2959/2957/5430 5 Dengue_virus_type_1 R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 2962/2960/2959/2957/5430 5 Dengue_virus_type_1 R-HSA-75953 RNA Polymerase II Transcription Initiation 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 2962/2960/2959/2957/5430 5 Dengue_virus_type_1 R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 2962/2960/2959/2957/5430 5 Dengue_virus_type_1 R-HSA-9020591 Interleukin-12 signaling 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 3717/3586/3458/7297/3716 5 Dengue_virus_type_1 R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 4/106 25/10654 9.969580213758398e-5 6.017353771875604e-4 3.7979353195270087e-4 8850/6772/1387/2033 4 Dengue_virus_type_1 R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 7/106 110/10654 1.0861024442425021e-4 6.363276845042179e-4 4.0162694090996e-4 2353/3576/3552/3725/4790/3569/5970 7 Dengue_virus_type_1 R-HSA-450341 Activation of the AP-1 family of transcription factors 3/106 10/10654 1.0919232455989537e-4 6.363276845042179e-4 4.0162694090996e-4 2353/3725/1386 3 Dengue_virus_type_1 R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 3/106 10/10654 1.0919232455989537e-4 6.363276845042179e-4 4.0162694090996e-4 8850/1387/2033 3 Dengue_virus_type_1 R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 6/106 80/10654 1.3925798827435726e-4 8.023159097170356e-4 5.063926846340264e-4 3434/6772/4599/3661/3716/23586 6 Dengue_virus_type_1 R-HSA-2586552 Signaling by Leptin 3/106 11/10654 1.4905367224680926e-4 8.491035036981157e-4 5.359233159435838e-4 3717/9021/5781 3 Dengue_virus_type_1 R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 3/106 12/10654 1.9730160412504728e-4 0.0011114657032377665 7.015168146668349e-4 64135/57506/23586 3 Dengue_virus_type_1 R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 5/106 55/10654 2.07769021329253e-4 0.0011575702616915522 7.306163387402302e-4 3654/7189/4790/5970/3656 5 Dengue_virus_type_1 R-HSA-1679131 Trafficking and processing of endosomal TLR 3/106 13/10654 2.5463875361552893e-4 0.0014032809574247083 8.85700012575753e-4 54106/7098/51284 3 Dengue_virus_type_1 R-HSA-3371568 Attenuation phase 3/106 14/10654 3.2174493346276634e-4 0.0017353689496342822 0.001095301901149843 3320/1387/2033 3 Dengue_virus_type_1 R-HSA-8941856 RUNX3 regulates NOTCH signaling 3/106 14/10654 3.2174493346276634e-4 0.0017353689496342822 0.001095301901149843 8850/1387/2033 3 Dengue_virus_type_1 R-HSA-193704 p75 NTR receptor-mediated signalling 6/106 97/10654 3.99603484037572e-4 0.0021326206990215685 0.0013460327883370847 3654/4615/7189/4804/4790/5970 6 Dengue_virus_type_1 R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 5/106 65/10654 4.560048609537547e-4 0.002408275671912017 0.0015200162031791824 2962/2353/3725/5430/1386 5 Dengue_virus_type_1 R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 3/106 16/10654 4.878722431679952e-4 0.0025500126524347793 0.001609475441378953 8850/1387/2033 3 Dengue_virus_type_1 R-HSA-73887 Death Receptor Signalling 7/106 141/10654 5.016063080590139e-4 0.0025950448794481635 0.0016378981487641271 7124/3654/4615/7189/4804/4790/5970 7 Dengue_virus_type_1 R-HSA-5689896 Ovarian tumor domain proteases 4/106 38/10654 5.267483469995212e-4 0.0026975900194823963 0.001702620919594412 64135/7189/57506/23586 4 Dengue_virus_type_1 R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 6/106 103/10654 5.510941231285975e-4 0.0027940472042619897 0.0017635011940115124 51135/3654/4615/7189/5781/3556 6 Dengue_virus_type_1 R-HSA-6788467 IL-6-type cytokine receptor ligand interactions 3/106 17/10654 5.881429367284286e-4 0.0029523610784288447 0.0018634231658722488 3717/7297/3716 3 Dengue_virus_type_1 R-HSA-2559583 Cellular Senescence 8/106 195/10654 7.114679108685945e-4 0.00353641402755272 0.0022320561909602967 2353/3576/3456/3552/3725/4790/3569/5970 8 Dengue_virus_type_1 R-HSA-9006931 Signaling by Nuclear Receptors 10/106 299/10654 7.6950202359387e-4 0.003769040710386929 0.0023788817106978645 2962/2353/8850/3320/3725/2957/1387/5430/2033/1386 10 Dengue_virus_type_1 R-HSA-167172 Transcription of the HIV genome 5/106 73/10654 7.787349645964273e-4 0.003769040710386929 0.0023788817106978645 2962/2960/2959/2957/5430 5 Dengue_virus_type_1 R-HSA-199418 Negative regulation of the PI3K/AKT network 6/106 110/10654 7.805705613227368e-4 0.003769040710386929 0.0023788817106978645 51135/3654/4615/7189/5781/3556 6 Dengue_virus_type_1 R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 13/106 473/10654 8.062232399371029e-4 0.003856180968378407 0.002433881479055405 3717/54106/2962/60/6772/4916/3320/8651/533/5781/5777/5430/5770 13 Dengue_virus_type_1 R-HSA-6807505 RNA polymerase II transcribes snRNA genes 5/106 74/10654 8.286371808802624e-4 0.003926346268283113 0.00247816726992228 2962/2960/2959/2957/5430 5 Dengue_virus_type_1 R-HSA-2262752 Cellular responses to stress 13/106 479/10654 9.057175580625575e-4 0.004251840758682562 0.002683607579444615 2353/2908/3576/3456/3552/3320/533/3725/4790/1387/3569/2033/5970 13 Dengue_virus_type_1 R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 3/106 20/10654 9.648384221695954e-4 0.004487826422385182 0.0028325531660024815 8850/1387/2033 3 Dengue_virus_type_2 R-HSA-909733 Interferon alpha/beta signaling 32/106 69/10654 1.7574415942985964e-47 8.910228883093883e-45 5.623813101755508e-45 3449/3440/3455/3448/10379/9021/3443/3660/3665/3434/3456/3444/3446/3452/6773/6772/3454/7297/8651/3663/5781/5777/3659/3662/4599/3445/3664/3451/3661/3441/5770/3716 32 Dengue_virus_type_2 R-HSA-912694 Regulation of IFNA signaling 22/106 26/10654 1.2720732510224532e-41 3.224705691341919e-39 2.035317201635925e-39 3449/3440/3455/3448/9021/3443/3456/3444/3446/3452/6773/6772/3454/7297/8651/5781/5777/3445/3451/3441/5770/3716 22 Dengue_virus_type_2 R-HSA-913531 Interferon Signaling 37/106 199/10654 5.65871817941487e-38 9.56323372321113e-36 6.035966058042528e-36 3449/3717/3440/3455/3448/10379/9021/3459/3443/3660/3665/3434/3456/3444/3446/3452/6773/6772/3458/3460/3454/7297/8651/3663/5781/5777/3659/3662/4599/3445/3664/3451/3661/3441/5770/3716/23586 37 Dengue_virus_type_2 R-HSA-449147 Signaling by Interleukins 46/106 461/10654 4.754089226819692e-35 6.0258080949939596e-33 3.8032713814557536e-33 3717/59307/51135/3605/3557/7124/11213/3559/3627/3586/3654/2353/9021/3576/29110/282618/3563/4615/7189/53832/3554/3553/163702/6773/6772/3552/6352/3458/3320/7297/8651/3588/5781/3725/5777/4790/3662/3569/54472/5970/6597/3146/3656/3556/3716/1386 46 Dengue_virus_type_2 R-HSA-933541 TRAF6 mediated IRF7 activation 20/106 29/10654 1.2673785921280584e-34 1.2851218924178512e-32 8.111222989619573e-33 3449/64135/3440/3448/3443/3665/29110/7189/3456/3444/3446/3452/57506/1387/3445/2033/3451/3661/3441/23586 20 Dengue_virus_type_2 R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 23/106 78/10654 1.58046634827272e-28 1.3354940642904485e-26 8.429153857454507e-27 3449/64135/3440/3448/3443/3665/29110/7189/3456/3444/3446/3452/57506/4790/1387/3445/2033/5970/3146/3451/3661/3441/23586 23 Dengue_virus_type_2 R-HSA-168898 Toll-like Receptor Cascades 24/106 155/10654 1.8524810977659753e-22 1.3417255950962136e-20 8.468485018358744e-21 54106/7097/59307/7099/51135/11213/3654/2353/3665/29110/4615/7189/929/7098/8651/5781/3725/51284/4790/5970/3146/3661/3656/1386 24 Dengue_virus_type_2 R-HSA-877312 Regulation of IFNG signaling 11/106 14/10654 1.9732920662134752e-20 1.207400383796255e-18 7.620673033822517e-19 3717/9021/3459/6772/3458/3460/8651/5781/5777/5770/3716 11 Dengue_virus_type_2 R-HSA-877300 Interferon gamma signaling 19/106 92/10654 2.1433142907625828e-20 1.207400383796255e-18 7.620673033822517e-19 3717/10379/9021/3459/3660/3665/6772/3458/3460/8651/3663/5781/5777/3659/3662/3664/3661/5770/3716 19 Dengue_virus_type_2 R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 21/106 129/10654 3.5147192561890846e-20 1.781962662887866e-18 1.124710161980507e-18 7097/59307/7099/51135/11213/3654/2353/3665/29110/4615/7189/929/8651/5781/3725/4790/5970/3146/3661/3656/1386 21 Dengue_virus_type_2 R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 17/106 95/10654 3.303959813687028e-17 1.3959230212827693e-15 8.810559503165408e-16 7097/59307/7099/51135/11213/3654/2353/4615/7189/929/8651/3725/4790/5970/3146/3656/1386 17 Dengue_virus_type_2 R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 17/106 95/10654 3.303959813687028e-17 1.3959230212827693e-15 8.810559503165408e-16 7097/59307/7099/51135/11213/3654/2353/4615/7189/929/8651/3725/4790/5970/3146/3656/1386 17 Dengue_virus_type_2 R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 17/106 98/10654 5.75059687090067e-17 2.0825375811047427e-15 1.314422141920153e-15 7097/59307/7099/51135/11213/3654/2353/4615/7189/929/8651/3725/4790/5970/3146/3656/1386 17 Dengue_virus_type_2 R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 17/106 98/10654 5.75059687090067e-17 2.0825375811047427e-15 1.314422141920153e-15 7097/59307/7099/51135/11213/3654/2353/4615/7189/929/8651/3725/4790/5970/3146/3656/1386 17 Dengue_virus_type_2 R-HSA-446652 Interleukin-1 family signaling 19/106 140/10654 8.786919653367847e-17 2.969978842838332e-15 1.8745428593851407e-15 59307/51135/3557/11213/3654/29110/4615/7189/3554/3553/3552/5781/5777/4790/54472/5970/3146/3656/3556 19 Dengue_virus_type_2 R-HSA-6783783 Interleukin-10 signaling 13/106 47/10654 4.670556516472278e-16 1.479982596157153e-14 9.341113032944557e-15 3557/7124/3627/3586/3576/3554/3553/3552/6352/7297/3588/3569/3716 13 Dengue_virus_type_2 R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 16/106 93/10654 5.818395242368237e-16 1.6388479932670535e-14 1.03438137642102e-14 54106/7099/51135/3654/2353/3665/4615/7189/929/3725/51284/4790/5970/3146/3656/1386 16 Dengue_virus_type_2 R-HSA-975155 MyD88 dependent cascade initiated on endosome 16/106 93/10654 5.818395242368237e-16 1.6388479932670535e-14 1.03438137642102e-14 54106/7099/51135/3654/2353/3665/4615/7189/929/3725/51284/4790/5970/3146/3656/1386 16 Dengue_virus_type_2 R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 16/106 97/10654 1.1734037086272284e-15 3.1311351593368675e-14 1.976258877687964e-14 54106/7099/51135/3654/2353/3665/4615/7189/929/3725/51284/4790/5970/3146/3656/1386 16 Dengue_virus_type_2 R-HSA-918233 TRAF3-dependent IRF activation pathway 9/106 14/10654 1.2989261473766412e-15 3.292777783599786e-14 2.0782818358026256e-14 64135/3665/29110/3456/57506/1387/2033/3661/23586 9 Dengue_virus_type_2 R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 16/106 108/10654 6.8938557814243345e-15 1.664373752943875e-13 1.0504923095503749e-13 3717/3605/7124/3586/2353/9021/3576/3553/6772/3552/3320/7297/8651/3662/3569/3716 16 Dengue_virus_type_2 R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 15/106 92/10654 1.1653134545012053e-14 2.685517824691414e-13 1.6950013883653895e-13 54106/7099/51135/3654/2353/4615/7189/929/3725/51284/4790/5970/3146/3656/1386 15 Dengue_virus_type_2 R-HSA-8854691 Interleukin-20 family signaling 10/106 25/10654 1.779801307219309e-14 3.9233011424356074e-13 2.476245297000778e-13 3717/282618/53832/163702/6773/6772/7297/3588/5781/3716 10 Dengue_virus_type_2 R-HSA-166166 MyD88-independent TLR4 cascade 15/106 99/10654 3.6193294066202875e-14 7.340000036625943e-13 4.632741640473968e-13 7099/3654/2353/3665/29110/7189/929/5781/3725/4790/5970/3146/3661/3656/1386 15 Dengue_virus_type_2 R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 15/106 99/10654 3.6193294066202875e-14 7.340000036625943e-13 4.632741640473968e-13 7099/3654/2353/3665/29110/7189/929/5781/3725/4790/5970/3146/3661/3656/1386 15 Dengue_virus_type_2 R-HSA-9020702 Interleukin-1 signaling 15/106 103/10654 6.64377024230364e-14 1.2955351972492097e-12 8.176947990527556e-13 51135/3557/11213/3654/4615/7189/3554/3553/3552/4790/54472/5970/3146/3656/3556 15 Dengue_virus_type_2 R-HSA-1059683 Interleukin-6 signaling 7/106 11/10654 2.5227715417303493e-12 4.737204339471434e-11 2.989951456865599e-11 3717/9021/6772/7297/5781/3569/3716 7 Dengue_virus_type_2 R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 13/106 94/10654 6.812061115392862e-12 1.2334696376800647e-10 7.785212703306129e-11 3654/2353/3665/29110/7189/7098/3725/4790/5970/3146/3661/3656/1386 13 Dengue_virus_type_2 R-HSA-5260271 Diseases of Immune System 8/106 24/10654 4.73635909568104e-11 7.787012212413498e-10 4.914879502903983e-10 7097/7099/51135/4615/929/7098/4790/5970 8 Dengue_virus_type_2 R-HSA-5602358 Diseases associated with the TLR signaling cascade 8/106 24/10654 4.73635909568104e-11 7.787012212413498e-10 4.914879502903983e-10 7097/7099/51135/4615/929/7098/4790/5970 8 Dengue_virus_type_2 R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 7/106 15/10654 4.7612895184382334e-11 7.787012212413498e-10 4.914879502903983e-10 54106/51135/3654/3665/4615/7189/51284 7 Dengue_virus_type_2 R-HSA-983231 Factors involved in megakaryocyte development and platelet production 15/106 168/10654 9.251550965490115e-11 1.4657926060948402e-9 9.251550965490116e-10 3449/3717/3440/60/3448/3443/3660/3456/3444/3446/3452/3659/3445/3451/3441 15 Dengue_virus_type_2 R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 11/106 85/10654 6.450431278633407e-10 9.343910452191821e-9 5.897537169036258e-9 51135/3654/2353/4615/7189/3725/4790/5970/3146/3656/1386 11 Dengue_virus_type_2 R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 11/106 85/10654 6.450431278633407e-10 9.343910452191821e-9 5.897537169036258e-9 51135/3654/2353/4615/7189/3725/4790/5970/3146/3656/1386 11 Dengue_virus_type_2 R-HSA-975871 MyD88 cascade initiated on plasma membrane 11/106 85/10654 6.450431278633407e-10 9.343910452191821e-9 5.897537169036258e-9 51135/3654/2353/4615/7189/3725/4790/5970/3146/3656/1386 11 Dengue_virus_type_2 R-HSA-6783589 Interleukin-6 family signaling 7/106 24/10654 2.379413669458972e-9 3.260439811934321e-8 2.057871281694246e-8 3717/9021/6772/7297/5781/3569/3716 7 Dengue_virus_type_2 R-HSA-933542 TRAF6 mediated NF-kB activation 7/106 24/10654 2.379413669458972e-9 3.260439811934321e-8 2.057871281694246e-8 64135/7189/57506/4790/5970/3146/23586 7 Dengue_virus_type_2 R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 8/106 38/10654 2.8072866695909013e-9 3.7455114249541766e-8 2.3640308796554956e-8 6599/6601/8289/2033/6598/6605/6597/6602 8 Dengue_virus_type_2 R-HSA-193639 p75NTR signals via NF-kB 6/106 16/10654 6.212399252262004e-9 8.076119027940605e-8 5.097353232625235e-8 3654/4615/7189/4804/4790/5970 6 Dengue_virus_type_2 R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 9/106 63/10654 1.025740612339184e-8 1.3001262261399157e-7 8.205924898713472e-8 3665/29110/4615/7098/4790/1387/2033/5970/3661 9 Dengue_virus_type_2 R-HSA-8878171 Transcriptional regulation by RUNX1 15/106 239/10654 1.2490645939752686e-8 1.544574997915759e-7 9.748796831026487e-8 6599/6601/8861/3559/9021/8850/8289/3458/5781/1387/2033/6598/6605/6597/6602 15 Dengue_virus_type_2 R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 6/106 18/10654 1.4170759952828179e-8 1.7106131657342588e-7 1.0796769487869089e-7 7099/3665/29110/929/5781/3661 6 Dengue_virus_type_2 R-HSA-110056 MAPK3 (ERK1) activation 5/106 10/10654 2.1477557826350696e-8 2.5323539111534425e-7 1.5983298847516797e-7 3717/7297/5781/3569/3716 5 Dengue_virus_type_2 R-HSA-5603041 IRAK4 deficiency (TLR2/4) 5/106 11/10654 3.906454026998454e-8 4.5013004356550367e-7 2.8410574741806936e-7 7097/7099/51135/4615/929 5 Dengue_virus_type_2 R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 6/106 21/10654 4.043106777741517e-8 4.555233636255443e-7 2.875098153060634e-7 29110/4615/7098/4790/5970/3661 6 Dengue_virus_type_2 R-HSA-3247509 Chromatin modifying enzymes 15/106 274/10654 7.731519772862207e-8 8.340171329449231e-7 5.264013462374268e-7 3717/6599/6601/60/8850/8289/4790/1387/2033/5970/6598/6605/6597/6602/1386 15 Dengue_virus_type_2 R-HSA-4839726 Chromatin organization 15/106 274/10654 7.731519772862207e-8 8.340171329449231e-7 5.264013462374268e-7 3717/6599/6601/60/8850/8289/4790/1387/2033/5970/6598/6605/6597/6602/1386 15 Dengue_virus_type_2 R-HSA-982772 Growth hormone receptor signaling 6/106 24/10654 9.78859334677603e-8 1.0339201722532182e-6 6.525728897850687e-7 3717/9021/6772/8651/5777/5770 6 Dengue_virus_type_2 R-HSA-209560 NF-kB is activated and signals survival 5/106 13/10654 1.0711088656166803e-7 1.1082697854441977e-6 6.994996673415056e-7 3654/7189/4804/4790/5970 5 Dengue_virus_type_2 R-HSA-448424 Interleukin-17 signaling 8/106 72/10654 5.197737078374082e-7 5.270505397471319e-6 3.3265517301594125e-6 3605/3654/2353/7189/3725/4790/3656/1386 8 Dengue_virus_type_2 R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 6/106 33/10654 7.4908383316751e-7 7.4467745767828944e-6 4.700133855168691e-6 3654/7189/4790/5970/3146/3656 6 Dengue_virus_type_2 R-HSA-3214858 RMTs methylate histone arginines 8/106 79/10654 1.0697273835103878e-6 1.0429841989226281e-5 6.582937744679309e-6 3717/6599/6601/8289/6598/6605/6597/6602 8 Dengue_virus_type_2 R-HSA-5602498 MyD88 deficiency (TLR2/4) 4/106 10/10654 1.8567309022384807e-6 1.776155787613037e-5 1.1210450730496486e-5 7097/7099/4615/929 4 Dengue_virus_type_2 R-HSA-9018519 Estrogen-dependent gene expression 10/106 150/10654 2.273195350095612e-6 2.134277856478658e-5 1.347078725982585e-5 2962/2353/8850/3320/3725/2957/1387/5430/2033/1386 10 Dengue_virus_type_2 R-HSA-112409 RAF-independent MAPK1/3 activation 5/106 23/10654 2.5872019074185484e-6 2.3849297582930985e-5 1.5052811097707918e-5 3717/7297/5781/3569/3716 5 Dengue_virus_type_2 R-HSA-193692 Regulated proteolysis of p75NTR 4/106 11/10654 2.895397394791909e-6 2.575379787999119e-5 1.625486256725282e-5 7189/4804/4790/5970 4 Dengue_virus_type_2 R-HSA-9020956 Interleukin-27 signaling 4/106 11/10654 2.895397394791909e-6 2.575379787999119e-5 1.625486256725282e-5 3717/6772/7297/3716 4 Dengue_virus_type_2 R-HSA-450294 MAP kinase activation 7/106 64/10654 3.0821716106451393e-6 2.6942431148225612e-5 1.7005084748386976e-5 3654/2353/7189/3725/4790/3656/1386 7 Dengue_virus_type_2 R-HSA-449836 Other interleukin signaling 5/106 24/10654 3.2422850584582233e-6 2.7861669909124053e-5 1.7585274893332735e-5 282618/163702/7297/3588/3716 5 Dengue_virus_type_2 R-HSA-8984722 Interleukin-35 Signalling 4/106 12/10654 4.30987661209511e-6 3.572937157855684e-5 2.255108265313252e-5 3717/6772/7297/3716 4 Dengue_virus_type_2 R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 4/106 12/10654 4.30987661209511e-6 3.572937157855684e-5 2.255108265313252e-5 3665/29110/7098/3661 4 Dengue_virus_type_2 R-HSA-451927 Interleukin-2 family signaling 6/106 44/10654 4.369272264044426e-6 3.572937157855684e-5 2.255108265313252e-5 3717/3559/3563/6772/5777/3716 6 Dengue_virus_type_2 R-HSA-912526 Interleukin receptor SHC signaling 5/106 27/10654 6.013804016258539e-6 4.8396803749890146e-5 3.0546306114329084e-5 3717/3559/3563/5777/3716 5 Dengue_virus_type_2 R-HSA-209543 p75NTR recruits signalling complexes 4/106 13/10654 6.177772490109953e-6 4.893954144508978e-5 3.0888862450549765e-5 3654/4615/7189/4804 4 Dengue_virus_type_2 R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 6/106 48/10654 7.3548221188321364e-6 5.736761252689066e-5 3.620835504655821e-5 3717/3559/3563/5781/5777/3716 6 Dengue_virus_type_2 R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 4/106 16/10654 1.5367420091186213e-5 1.1804972706411227e-4 7.450870347241801e-5 7099/7189/929/3656 4 Dengue_virus_type_2 R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 5/106 34/10654 1.961227957654317e-5 1.4651984854343705e-4 9.247801091498985e-5 64135/29110/57506/3661/23586 5 Dengue_virus_type_2 R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 4/106 17/10654 1.994233988597015e-5 1.4651984854343705e-4 9.247801091498985e-5 4615/7098/4790/5970 4 Dengue_virus_type_2 R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 4/106 17/10654 1.994233988597015e-5 1.4651984854343705e-4 9.247801091498985e-5 7099/7189/929/3656 4 Dengue_virus_type_2 R-HSA-447115 Interleukin-12 family signaling 6/106 57/10654 2.022956488765403e-5 1.4651984854343705e-4 9.247801091498985e-5 3717/3586/6772/3458/7297/3716 6 Dengue_virus_type_2 R-HSA-5686938 Regulation of TLR by endogenous ligand 4/106 19/10654 3.1983399246876657e-5 2.28388498847415e-4 1.4415053181690888e-4 7097/7099/929/3146 4 Dengue_virus_type_2 R-HSA-5621575 CD209 (DC-SIGN) signaling 4/106 21/10654 4.86351310286388e-5 3.3778097851397084e-4 2.1319509492006048e-4 4790/1387/2033/5970 4 Dengue_virus_type_2 R-HSA-9008059 Interleukin-37 signaling 4/106 21/10654 4.86351310286388e-5 3.3778097851397084e-4 2.1319509492006048e-4 59307/29110/5781/5777 4 Dengue_virus_type_2 R-HSA-1433557 Signaling by SCF-KIT 5/106 43/10654 6.319339888081125e-5 4.3296017881853114e-4 2.7326875191702166e-4 3717/6772/8651/5781/5777 5 Dengue_virus_type_2 R-HSA-8939211 ESR-mediated signaling 10/106 223/10654 7.271628471820228e-5 4.915620846950474e-4 3.1025614813099637e-4 2962/2353/8850/3320/3725/2957/1387/5430/2033/1386 10 Dengue_virus_type_2 R-HSA-1169408 ISG15 antiviral mechanism 6/106 72/10654 7.720636181470404e-5 5.150477031586178e-4 3.2507941816717497e-4 3434/6772/4599/3661/3716/23586 6 Dengue_virus_type_2 R-HSA-167161 HIV Transcription Initiation 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 2962/2960/2959/2957/5430 5 Dengue_virus_type_2 R-HSA-167162 RNA Polymerase II HIV Promoter Escape 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 2962/2960/2959/2957/5430 5 Dengue_virus_type_2 R-HSA-73776 RNA Polymerase II Promoter Escape 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 2962/2960/2959/2957/5430 5 Dengue_virus_type_2 R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 2962/2960/2959/2957/5430 5 Dengue_virus_type_2 R-HSA-75953 RNA Polymerase II Transcription Initiation 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 2962/2960/2959/2957/5430 5 Dengue_virus_type_2 R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 2962/2960/2959/2957/5430 5 Dengue_virus_type_2 R-HSA-9020591 Interleukin-12 signaling 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 3717/3586/3458/7297/3716 5 Dengue_virus_type_2 R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 4/106 25/10654 9.969580213758398e-5 6.017353771875604e-4 3.7979353195270087e-4 8850/6772/1387/2033 4 Dengue_virus_type_2 R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 7/106 110/10654 1.0861024442425021e-4 6.363276845042179e-4 4.0162694090996e-4 2353/3576/3552/3725/4790/3569/5970 7 Dengue_virus_type_2 R-HSA-450341 Activation of the AP-1 family of transcription factors 3/106 10/10654 1.0919232455989537e-4 6.363276845042179e-4 4.0162694090996e-4 2353/3725/1386 3 Dengue_virus_type_2 R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 3/106 10/10654 1.0919232455989537e-4 6.363276845042179e-4 4.0162694090996e-4 8850/1387/2033 3 Dengue_virus_type_2 R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 6/106 80/10654 1.3925798827435726e-4 8.023159097170356e-4 5.063926846340264e-4 3434/6772/4599/3661/3716/23586 6 Dengue_virus_type_2 R-HSA-2586552 Signaling by Leptin 3/106 11/10654 1.4905367224680926e-4 8.491035036981157e-4 5.359233159435838e-4 3717/9021/5781 3 Dengue_virus_type_2 R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 3/106 12/10654 1.9730160412504728e-4 0.0011114657032377665 7.015168146668349e-4 64135/57506/23586 3 Dengue_virus_type_2 R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 5/106 55/10654 2.07769021329253e-4 0.0011575702616915522 7.306163387402302e-4 3654/7189/4790/5970/3656 5 Dengue_virus_type_2 R-HSA-1679131 Trafficking and processing of endosomal TLR 3/106 13/10654 2.5463875361552893e-4 0.0014032809574247083 8.85700012575753e-4 54106/7098/51284 3 Dengue_virus_type_2 R-HSA-3371568 Attenuation phase 3/106 14/10654 3.2174493346276634e-4 0.0017353689496342822 0.001095301901149843 3320/1387/2033 3 Dengue_virus_type_2 R-HSA-8941856 RUNX3 regulates NOTCH signaling 3/106 14/10654 3.2174493346276634e-4 0.0017353689496342822 0.001095301901149843 8850/1387/2033 3 Dengue_virus_type_2 R-HSA-193704 p75 NTR receptor-mediated signalling 6/106 97/10654 3.99603484037572e-4 0.0021326206990215685 0.0013460327883370847 3654/4615/7189/4804/4790/5970 6 Dengue_virus_type_2 R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 5/106 65/10654 4.560048609537547e-4 0.002408275671912017 0.0015200162031791824 2962/2353/3725/5430/1386 5 Dengue_virus_type_2 R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 3/106 16/10654 4.878722431679952e-4 0.0025500126524347793 0.001609475441378953 8850/1387/2033 3 Dengue_virus_type_2 R-HSA-73887 Death Receptor Signalling 7/106 141/10654 5.016063080590139e-4 0.0025950448794481635 0.0016378981487641271 7124/3654/4615/7189/4804/4790/5970 7 Dengue_virus_type_2 R-HSA-5689896 Ovarian tumor domain proteases 4/106 38/10654 5.267483469995212e-4 0.0026975900194823963 0.001702620919594412 64135/7189/57506/23586 4 Dengue_virus_type_2 R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 6/106 103/10654 5.510941231285975e-4 0.0027940472042619897 0.0017635011940115124 51135/3654/4615/7189/5781/3556 6 Dengue_virus_type_2 R-HSA-6788467 IL-6-type cytokine receptor ligand interactions 3/106 17/10654 5.881429367284286e-4 0.0029523610784288447 0.0018634231658722488 3717/7297/3716 3 Dengue_virus_type_2 R-HSA-2559583 Cellular Senescence 8/106 195/10654 7.114679108685945e-4 0.00353641402755272 0.0022320561909602967 2353/3576/3456/3552/3725/4790/3569/5970 8 Dengue_virus_type_2 R-HSA-9006931 Signaling by Nuclear Receptors 10/106 299/10654 7.6950202359387e-4 0.003769040710386929 0.0023788817106978645 2962/2353/8850/3320/3725/2957/1387/5430/2033/1386 10 Dengue_virus_type_2 R-HSA-167172 Transcription of the HIV genome 5/106 73/10654 7.787349645964273e-4 0.003769040710386929 0.0023788817106978645 2962/2960/2959/2957/5430 5 Dengue_virus_type_2 R-HSA-199418 Negative regulation of the PI3K/AKT network 6/106 110/10654 7.805705613227368e-4 0.003769040710386929 0.0023788817106978645 51135/3654/4615/7189/5781/3556 6 Dengue_virus_type_2 R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 13/106 473/10654 8.062232399371029e-4 0.003856180968378407 0.002433881479055405 3717/54106/2962/60/6772/4916/3320/8651/533/5781/5777/5430/5770 13 Dengue_virus_type_2 R-HSA-6807505 RNA polymerase II transcribes snRNA genes 5/106 74/10654 8.286371808802624e-4 0.003926346268283113 0.00247816726992228 2962/2960/2959/2957/5430 5 Dengue_virus_type_2 R-HSA-2262752 Cellular responses to stress 13/106 479/10654 9.057175580625575e-4 0.004251840758682562 0.002683607579444615 2353/2908/3576/3456/3552/3320/533/3725/4790/1387/3569/2033/5970 13 Dengue_virus_type_2 R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 3/106 20/10654 9.648384221695954e-4 0.004487826422385182 0.0028325531660024815 8850/1387/2033 3 Dengue_virus_type_3 R-HSA-909733 Interferon alpha/beta signaling 32/106 69/10654 1.7574415942985964e-47 8.910228883093883e-45 5.623813101755508e-45 3449/3440/3455/3448/10379/9021/3443/3660/3665/3434/3456/3444/3446/3452/6773/6772/3454/7297/8651/3663/5781/5777/3659/3662/4599/3445/3664/3451/3661/3441/5770/3716 32 Dengue_virus_type_3 R-HSA-912694 Regulation of IFNA signaling 22/106 26/10654 1.2720732510224532e-41 3.224705691341919e-39 2.035317201635925e-39 3449/3440/3455/3448/9021/3443/3456/3444/3446/3452/6773/6772/3454/7297/8651/5781/5777/3445/3451/3441/5770/3716 22 Dengue_virus_type_3 R-HSA-913531 Interferon Signaling 37/106 199/10654 5.65871817941487e-38 9.56323372321113e-36 6.035966058042528e-36 3449/3717/3440/3455/3448/10379/9021/3459/3443/3660/3665/3434/3456/3444/3446/3452/6773/6772/3458/3460/3454/7297/8651/3663/5781/5777/3659/3662/4599/3445/3664/3451/3661/3441/5770/3716/23586 37 Dengue_virus_type_3 R-HSA-449147 Signaling by Interleukins 46/106 461/10654 4.754089226819692e-35 6.0258080949939596e-33 3.8032713814557536e-33 3717/59307/51135/3605/3557/7124/11213/3559/3627/3586/3654/2353/9021/3576/29110/282618/3563/4615/7189/53832/3554/3553/163702/6773/6772/3552/6352/3458/3320/7297/8651/3588/5781/3725/5777/4790/3662/3569/54472/5970/6597/3146/3656/3556/3716/1386 46 Dengue_virus_type_3 R-HSA-933541 TRAF6 mediated IRF7 activation 20/106 29/10654 1.2673785921280584e-34 1.2851218924178512e-32 8.111222989619573e-33 3449/64135/3440/3448/3443/3665/29110/7189/3456/3444/3446/3452/57506/1387/3445/2033/3451/3661/3441/23586 20 Dengue_virus_type_3 R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 23/106 78/10654 1.58046634827272e-28 1.3354940642904485e-26 8.429153857454507e-27 3449/64135/3440/3448/3443/3665/29110/7189/3456/3444/3446/3452/57506/4790/1387/3445/2033/5970/3146/3451/3661/3441/23586 23 Dengue_virus_type_3 R-HSA-168898 Toll-like Receptor Cascades 24/106 155/10654 1.8524810977659753e-22 1.3417255950962136e-20 8.468485018358744e-21 54106/7097/59307/7099/51135/11213/3654/2353/3665/29110/4615/7189/929/7098/8651/5781/3725/51284/4790/5970/3146/3661/3656/1386 24 Dengue_virus_type_3 R-HSA-877312 Regulation of IFNG signaling 11/106 14/10654 1.9732920662134752e-20 1.207400383796255e-18 7.620673033822517e-19 3717/9021/3459/6772/3458/3460/8651/5781/5777/5770/3716 11 Dengue_virus_type_3 R-HSA-877300 Interferon gamma signaling 19/106 92/10654 2.1433142907625828e-20 1.207400383796255e-18 7.620673033822517e-19 3717/10379/9021/3459/3660/3665/6772/3458/3460/8651/3663/5781/5777/3659/3662/3664/3661/5770/3716 19 Dengue_virus_type_3 R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 21/106 129/10654 3.5147192561890846e-20 1.781962662887866e-18 1.124710161980507e-18 7097/59307/7099/51135/11213/3654/2353/3665/29110/4615/7189/929/8651/5781/3725/4790/5970/3146/3661/3656/1386 21 Dengue_virus_type_3 R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 17/106 95/10654 3.303959813687028e-17 1.3959230212827693e-15 8.810559503165408e-16 7097/59307/7099/51135/11213/3654/2353/4615/7189/929/8651/3725/4790/5970/3146/3656/1386 17 Dengue_virus_type_3 R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 17/106 95/10654 3.303959813687028e-17 1.3959230212827693e-15 8.810559503165408e-16 7097/59307/7099/51135/11213/3654/2353/4615/7189/929/8651/3725/4790/5970/3146/3656/1386 17 Dengue_virus_type_3 R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 17/106 98/10654 5.75059687090067e-17 2.0825375811047427e-15 1.314422141920153e-15 7097/59307/7099/51135/11213/3654/2353/4615/7189/929/8651/3725/4790/5970/3146/3656/1386 17 Dengue_virus_type_3 R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 17/106 98/10654 5.75059687090067e-17 2.0825375811047427e-15 1.314422141920153e-15 7097/59307/7099/51135/11213/3654/2353/4615/7189/929/8651/3725/4790/5970/3146/3656/1386 17 Dengue_virus_type_3 R-HSA-446652 Interleukin-1 family signaling 19/106 140/10654 8.786919653367847e-17 2.969978842838332e-15 1.8745428593851407e-15 59307/51135/3557/11213/3654/29110/4615/7189/3554/3553/3552/5781/5777/4790/54472/5970/3146/3656/3556 19 Dengue_virus_type_3 R-HSA-6783783 Interleukin-10 signaling 13/106 47/10654 4.670556516472278e-16 1.479982596157153e-14 9.341113032944557e-15 3557/7124/3627/3586/3576/3554/3553/3552/6352/7297/3588/3569/3716 13 Dengue_virus_type_3 R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 16/106 93/10654 5.818395242368237e-16 1.6388479932670535e-14 1.03438137642102e-14 54106/7099/51135/3654/2353/3665/4615/7189/929/3725/51284/4790/5970/3146/3656/1386 16 Dengue_virus_type_3 R-HSA-975155 MyD88 dependent cascade initiated on endosome 16/106 93/10654 5.818395242368237e-16 1.6388479932670535e-14 1.03438137642102e-14 54106/7099/51135/3654/2353/3665/4615/7189/929/3725/51284/4790/5970/3146/3656/1386 16 Dengue_virus_type_3 R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 16/106 97/10654 1.1734037086272284e-15 3.1311351593368675e-14 1.976258877687964e-14 54106/7099/51135/3654/2353/3665/4615/7189/929/3725/51284/4790/5970/3146/3656/1386 16 Dengue_virus_type_3 R-HSA-918233 TRAF3-dependent IRF activation pathway 9/106 14/10654 1.2989261473766412e-15 3.292777783599786e-14 2.0782818358026256e-14 64135/3665/29110/3456/57506/1387/2033/3661/23586 9 Dengue_virus_type_3 R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 16/106 108/10654 6.8938557814243345e-15 1.664373752943875e-13 1.0504923095503749e-13 3717/3605/7124/3586/2353/9021/3576/3553/6772/3552/3320/7297/8651/3662/3569/3716 16 Dengue_virus_type_3 R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 15/106 92/10654 1.1653134545012053e-14 2.685517824691414e-13 1.6950013883653895e-13 54106/7099/51135/3654/2353/4615/7189/929/3725/51284/4790/5970/3146/3656/1386 15 Dengue_virus_type_3 R-HSA-8854691 Interleukin-20 family signaling 10/106 25/10654 1.779801307219309e-14 3.9233011424356074e-13 2.476245297000778e-13 3717/282618/53832/163702/6773/6772/7297/3588/5781/3716 10 Dengue_virus_type_3 R-HSA-166166 MyD88-independent TLR4 cascade 15/106 99/10654 3.6193294066202875e-14 7.340000036625943e-13 4.632741640473968e-13 7099/3654/2353/3665/29110/7189/929/5781/3725/4790/5970/3146/3661/3656/1386 15 Dengue_virus_type_3 R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 15/106 99/10654 3.6193294066202875e-14 7.340000036625943e-13 4.632741640473968e-13 7099/3654/2353/3665/29110/7189/929/5781/3725/4790/5970/3146/3661/3656/1386 15 Dengue_virus_type_3 R-HSA-9020702 Interleukin-1 signaling 15/106 103/10654 6.64377024230364e-14 1.2955351972492097e-12 8.176947990527556e-13 51135/3557/11213/3654/4615/7189/3554/3553/3552/4790/54472/5970/3146/3656/3556 15 Dengue_virus_type_3 R-HSA-1059683 Interleukin-6 signaling 7/106 11/10654 2.5227715417303493e-12 4.737204339471434e-11 2.989951456865599e-11 3717/9021/6772/7297/5781/3569/3716 7 Dengue_virus_type_3 R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 13/106 94/10654 6.812061115392862e-12 1.2334696376800647e-10 7.785212703306129e-11 3654/2353/3665/29110/7189/7098/3725/4790/5970/3146/3661/3656/1386 13 Dengue_virus_type_3 R-HSA-5260271 Diseases of Immune System 8/106 24/10654 4.73635909568104e-11 7.787012212413498e-10 4.914879502903983e-10 7097/7099/51135/4615/929/7098/4790/5970 8 Dengue_virus_type_3 R-HSA-5602358 Diseases associated with the TLR signaling cascade 8/106 24/10654 4.73635909568104e-11 7.787012212413498e-10 4.914879502903983e-10 7097/7099/51135/4615/929/7098/4790/5970 8 Dengue_virus_type_3 R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 7/106 15/10654 4.7612895184382334e-11 7.787012212413498e-10 4.914879502903983e-10 54106/51135/3654/3665/4615/7189/51284 7 Dengue_virus_type_3 R-HSA-983231 Factors involved in megakaryocyte development and platelet production 15/106 168/10654 9.251550965490115e-11 1.4657926060948402e-9 9.251550965490116e-10 3449/3717/3440/60/3448/3443/3660/3456/3444/3446/3452/3659/3445/3451/3441 15 Dengue_virus_type_3 R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 11/106 85/10654 6.450431278633407e-10 9.343910452191821e-9 5.897537169036258e-9 51135/3654/2353/4615/7189/3725/4790/5970/3146/3656/1386 11 Dengue_virus_type_3 R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 11/106 85/10654 6.450431278633407e-10 9.343910452191821e-9 5.897537169036258e-9 51135/3654/2353/4615/7189/3725/4790/5970/3146/3656/1386 11 Dengue_virus_type_3 R-HSA-975871 MyD88 cascade initiated on plasma membrane 11/106 85/10654 6.450431278633407e-10 9.343910452191821e-9 5.897537169036258e-9 51135/3654/2353/4615/7189/3725/4790/5970/3146/3656/1386 11 Dengue_virus_type_3 R-HSA-6783589 Interleukin-6 family signaling 7/106 24/10654 2.379413669458972e-9 3.260439811934321e-8 2.057871281694246e-8 3717/9021/6772/7297/5781/3569/3716 7 Dengue_virus_type_3 R-HSA-933542 TRAF6 mediated NF-kB activation 7/106 24/10654 2.379413669458972e-9 3.260439811934321e-8 2.057871281694246e-8 64135/7189/57506/4790/5970/3146/23586 7 Dengue_virus_type_3 R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 8/106 38/10654 2.8072866695909013e-9 3.7455114249541766e-8 2.3640308796554956e-8 6599/6601/8289/2033/6598/6605/6597/6602 8 Dengue_virus_type_3 R-HSA-193639 p75NTR signals via NF-kB 6/106 16/10654 6.212399252262004e-9 8.076119027940605e-8 5.097353232625235e-8 3654/4615/7189/4804/4790/5970 6 Dengue_virus_type_3 R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 9/106 63/10654 1.025740612339184e-8 1.3001262261399157e-7 8.205924898713472e-8 3665/29110/4615/7098/4790/1387/2033/5970/3661 9 Dengue_virus_type_3 R-HSA-8878171 Transcriptional regulation by RUNX1 15/106 239/10654 1.2490645939752686e-8 1.544574997915759e-7 9.748796831026487e-8 6599/6601/8861/3559/9021/8850/8289/3458/5781/1387/2033/6598/6605/6597/6602 15 Dengue_virus_type_3 R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 6/106 18/10654 1.4170759952828179e-8 1.7106131657342588e-7 1.0796769487869089e-7 7099/3665/29110/929/5781/3661 6 Dengue_virus_type_3 R-HSA-110056 MAPK3 (ERK1) activation 5/106 10/10654 2.1477557826350696e-8 2.5323539111534425e-7 1.5983298847516797e-7 3717/7297/5781/3569/3716 5 Dengue_virus_type_3 R-HSA-5603041 IRAK4 deficiency (TLR2/4) 5/106 11/10654 3.906454026998454e-8 4.5013004356550367e-7 2.8410574741806936e-7 7097/7099/51135/4615/929 5 Dengue_virus_type_3 R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 6/106 21/10654 4.043106777741517e-8 4.555233636255443e-7 2.875098153060634e-7 29110/4615/7098/4790/5970/3661 6 Dengue_virus_type_3 R-HSA-3247509 Chromatin modifying enzymes 15/106 274/10654 7.731519772862207e-8 8.340171329449231e-7 5.264013462374268e-7 3717/6599/6601/60/8850/8289/4790/1387/2033/5970/6598/6605/6597/6602/1386 15 Dengue_virus_type_3 R-HSA-4839726 Chromatin organization 15/106 274/10654 7.731519772862207e-8 8.340171329449231e-7 5.264013462374268e-7 3717/6599/6601/60/8850/8289/4790/1387/2033/5970/6598/6605/6597/6602/1386 15 Dengue_virus_type_3 R-HSA-982772 Growth hormone receptor signaling 6/106 24/10654 9.78859334677603e-8 1.0339201722532182e-6 6.525728897850687e-7 3717/9021/6772/8651/5777/5770 6 Dengue_virus_type_3 R-HSA-209560 NF-kB is activated and signals survival 5/106 13/10654 1.0711088656166803e-7 1.1082697854441977e-6 6.994996673415056e-7 3654/7189/4804/4790/5970 5 Dengue_virus_type_3 R-HSA-448424 Interleukin-17 signaling 8/106 72/10654 5.197737078374082e-7 5.270505397471319e-6 3.3265517301594125e-6 3605/3654/2353/7189/3725/4790/3656/1386 8 Dengue_virus_type_3 R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 6/106 33/10654 7.4908383316751e-7 7.4467745767828944e-6 4.700133855168691e-6 3654/7189/4790/5970/3146/3656 6 Dengue_virus_type_3 R-HSA-3214858 RMTs methylate histone arginines 8/106 79/10654 1.0697273835103878e-6 1.0429841989226281e-5 6.582937744679309e-6 3717/6599/6601/8289/6598/6605/6597/6602 8 Dengue_virus_type_3 R-HSA-5602498 MyD88 deficiency (TLR2/4) 4/106 10/10654 1.8567309022384807e-6 1.776155787613037e-5 1.1210450730496486e-5 7097/7099/4615/929 4 Dengue_virus_type_3 R-HSA-9018519 Estrogen-dependent gene expression 10/106 150/10654 2.273195350095612e-6 2.134277856478658e-5 1.347078725982585e-5 2962/2353/8850/3320/3725/2957/1387/5430/2033/1386 10 Dengue_virus_type_3 R-HSA-112409 RAF-independent MAPK1/3 activation 5/106 23/10654 2.5872019074185484e-6 2.3849297582930985e-5 1.5052811097707918e-5 3717/7297/5781/3569/3716 5 Dengue_virus_type_3 R-HSA-193692 Regulated proteolysis of p75NTR 4/106 11/10654 2.895397394791909e-6 2.575379787999119e-5 1.625486256725282e-5 7189/4804/4790/5970 4 Dengue_virus_type_3 R-HSA-9020956 Interleukin-27 signaling 4/106 11/10654 2.895397394791909e-6 2.575379787999119e-5 1.625486256725282e-5 3717/6772/7297/3716 4 Dengue_virus_type_3 R-HSA-450294 MAP kinase activation 7/106 64/10654 3.0821716106451393e-6 2.6942431148225612e-5 1.7005084748386976e-5 3654/2353/7189/3725/4790/3656/1386 7 Dengue_virus_type_3 R-HSA-449836 Other interleukin signaling 5/106 24/10654 3.2422850584582233e-6 2.7861669909124053e-5 1.7585274893332735e-5 282618/163702/7297/3588/3716 5 Dengue_virus_type_3 R-HSA-8984722 Interleukin-35 Signalling 4/106 12/10654 4.30987661209511e-6 3.572937157855684e-5 2.255108265313252e-5 3717/6772/7297/3716 4 Dengue_virus_type_3 R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 4/106 12/10654 4.30987661209511e-6 3.572937157855684e-5 2.255108265313252e-5 3665/29110/7098/3661 4 Dengue_virus_type_3 R-HSA-451927 Interleukin-2 family signaling 6/106 44/10654 4.369272264044426e-6 3.572937157855684e-5 2.255108265313252e-5 3717/3559/3563/6772/5777/3716 6 Dengue_virus_type_3 R-HSA-912526 Interleukin receptor SHC signaling 5/106 27/10654 6.013804016258539e-6 4.8396803749890146e-5 3.0546306114329084e-5 3717/3559/3563/5777/3716 5 Dengue_virus_type_3 R-HSA-209543 p75NTR recruits signalling complexes 4/106 13/10654 6.177772490109953e-6 4.893954144508978e-5 3.0888862450549765e-5 3654/4615/7189/4804 4 Dengue_virus_type_3 R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 6/106 48/10654 7.3548221188321364e-6 5.736761252689066e-5 3.620835504655821e-5 3717/3559/3563/5781/5777/3716 6 Dengue_virus_type_3 R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 4/106 16/10654 1.5367420091186213e-5 1.1804972706411227e-4 7.450870347241801e-5 7099/7189/929/3656 4 Dengue_virus_type_3 R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 5/106 34/10654 1.961227957654317e-5 1.4651984854343705e-4 9.247801091498985e-5 64135/29110/57506/3661/23586 5 Dengue_virus_type_3 R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 4/106 17/10654 1.994233988597015e-5 1.4651984854343705e-4 9.247801091498985e-5 4615/7098/4790/5970 4 Dengue_virus_type_3 R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 4/106 17/10654 1.994233988597015e-5 1.4651984854343705e-4 9.247801091498985e-5 7099/7189/929/3656 4 Dengue_virus_type_3 R-HSA-447115 Interleukin-12 family signaling 6/106 57/10654 2.022956488765403e-5 1.4651984854343705e-4 9.247801091498985e-5 3717/3586/6772/3458/7297/3716 6 Dengue_virus_type_3 R-HSA-5686938 Regulation of TLR by endogenous ligand 4/106 19/10654 3.1983399246876657e-5 2.28388498847415e-4 1.4415053181690888e-4 7097/7099/929/3146 4 Dengue_virus_type_3 R-HSA-5621575 CD209 (DC-SIGN) signaling 4/106 21/10654 4.86351310286388e-5 3.3778097851397084e-4 2.1319509492006048e-4 4790/1387/2033/5970 4 Dengue_virus_type_3 R-HSA-9008059 Interleukin-37 signaling 4/106 21/10654 4.86351310286388e-5 3.3778097851397084e-4 2.1319509492006048e-4 59307/29110/5781/5777 4 Dengue_virus_type_3 R-HSA-1433557 Signaling by SCF-KIT 5/106 43/10654 6.319339888081125e-5 4.3296017881853114e-4 2.7326875191702166e-4 3717/6772/8651/5781/5777 5 Dengue_virus_type_3 R-HSA-8939211 ESR-mediated signaling 10/106 223/10654 7.271628471820228e-5 4.915620846950474e-4 3.1025614813099637e-4 2962/2353/8850/3320/3725/2957/1387/5430/2033/1386 10 Dengue_virus_type_3 R-HSA-1169408 ISG15 antiviral mechanism 6/106 72/10654 7.720636181470404e-5 5.150477031586178e-4 3.2507941816717497e-4 3434/6772/4599/3661/3716/23586 6 Dengue_virus_type_3 R-HSA-167161 HIV Transcription Initiation 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 2962/2960/2959/2957/5430 5 Dengue_virus_type_3 R-HSA-167162 RNA Polymerase II HIV Promoter Escape 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 2962/2960/2959/2957/5430 5 Dengue_virus_type_3 R-HSA-73776 RNA Polymerase II Promoter Escape 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 2962/2960/2959/2957/5430 5 Dengue_virus_type_3 R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 2962/2960/2959/2957/5430 5 Dengue_virus_type_3 R-HSA-75953 RNA Polymerase II Transcription Initiation 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 2962/2960/2959/2957/5430 5 Dengue_virus_type_3 R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 2962/2960/2959/2957/5430 5 Dengue_virus_type_3 R-HSA-9020591 Interleukin-12 signaling 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 3717/3586/3458/7297/3716 5 Dengue_virus_type_3 R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 4/106 25/10654 9.969580213758398e-5 6.017353771875604e-4 3.7979353195270087e-4 8850/6772/1387/2033 4 Dengue_virus_type_3 R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 7/106 110/10654 1.0861024442425021e-4 6.363276845042179e-4 4.0162694090996e-4 2353/3576/3552/3725/4790/3569/5970 7 Dengue_virus_type_3 R-HSA-450341 Activation of the AP-1 family of transcription factors 3/106 10/10654 1.0919232455989537e-4 6.363276845042179e-4 4.0162694090996e-4 2353/3725/1386 3 Dengue_virus_type_3 R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 3/106 10/10654 1.0919232455989537e-4 6.363276845042179e-4 4.0162694090996e-4 8850/1387/2033 3 Dengue_virus_type_3 R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 6/106 80/10654 1.3925798827435726e-4 8.023159097170356e-4 5.063926846340264e-4 3434/6772/4599/3661/3716/23586 6 Dengue_virus_type_3 R-HSA-2586552 Signaling by Leptin 3/106 11/10654 1.4905367224680926e-4 8.491035036981157e-4 5.359233159435838e-4 3717/9021/5781 3 Dengue_virus_type_3 R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 3/106 12/10654 1.9730160412504728e-4 0.0011114657032377665 7.015168146668349e-4 64135/57506/23586 3 Dengue_virus_type_3 R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 5/106 55/10654 2.07769021329253e-4 0.0011575702616915522 7.306163387402302e-4 3654/7189/4790/5970/3656 5 Dengue_virus_type_3 R-HSA-1679131 Trafficking and processing of endosomal TLR 3/106 13/10654 2.5463875361552893e-4 0.0014032809574247083 8.85700012575753e-4 54106/7098/51284 3 Dengue_virus_type_3 R-HSA-3371568 Attenuation phase 3/106 14/10654 3.2174493346276634e-4 0.0017353689496342822 0.001095301901149843 3320/1387/2033 3 Dengue_virus_type_3 R-HSA-8941856 RUNX3 regulates NOTCH signaling 3/106 14/10654 3.2174493346276634e-4 0.0017353689496342822 0.001095301901149843 8850/1387/2033 3 Dengue_virus_type_3 R-HSA-193704 p75 NTR receptor-mediated signalling 6/106 97/10654 3.99603484037572e-4 0.0021326206990215685 0.0013460327883370847 3654/4615/7189/4804/4790/5970 6 Dengue_virus_type_3 R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 5/106 65/10654 4.560048609537547e-4 0.002408275671912017 0.0015200162031791824 2962/2353/3725/5430/1386 5 Dengue_virus_type_3 R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 3/106 16/10654 4.878722431679952e-4 0.0025500126524347793 0.001609475441378953 8850/1387/2033 3 Dengue_virus_type_3 R-HSA-73887 Death Receptor Signalling 7/106 141/10654 5.016063080590139e-4 0.0025950448794481635 0.0016378981487641271 7124/3654/4615/7189/4804/4790/5970 7 Dengue_virus_type_3 R-HSA-5689896 Ovarian tumor domain proteases 4/106 38/10654 5.267483469995212e-4 0.0026975900194823963 0.001702620919594412 64135/7189/57506/23586 4 Dengue_virus_type_3 R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 6/106 103/10654 5.510941231285975e-4 0.0027940472042619897 0.0017635011940115124 51135/3654/4615/7189/5781/3556 6 Dengue_virus_type_3 R-HSA-6788467 IL-6-type cytokine receptor ligand interactions 3/106 17/10654 5.881429367284286e-4 0.0029523610784288447 0.0018634231658722488 3717/7297/3716 3 Dengue_virus_type_3 R-HSA-2559583 Cellular Senescence 8/106 195/10654 7.114679108685945e-4 0.00353641402755272 0.0022320561909602967 2353/3576/3456/3552/3725/4790/3569/5970 8 Dengue_virus_type_3 R-HSA-9006931 Signaling by Nuclear Receptors 10/106 299/10654 7.6950202359387e-4 0.003769040710386929 0.0023788817106978645 2962/2353/8850/3320/3725/2957/1387/5430/2033/1386 10 Dengue_virus_type_3 R-HSA-167172 Transcription of the HIV genome 5/106 73/10654 7.787349645964273e-4 0.003769040710386929 0.0023788817106978645 2962/2960/2959/2957/5430 5 Dengue_virus_type_3 R-HSA-199418 Negative regulation of the PI3K/AKT network 6/106 110/10654 7.805705613227368e-4 0.003769040710386929 0.0023788817106978645 51135/3654/4615/7189/5781/3556 6 Dengue_virus_type_3 R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 13/106 473/10654 8.062232399371029e-4 0.003856180968378407 0.002433881479055405 3717/54106/2962/60/6772/4916/3320/8651/533/5781/5777/5430/5770 13 Dengue_virus_type_3 R-HSA-6807505 RNA polymerase II transcribes snRNA genes 5/106 74/10654 8.286371808802624e-4 0.003926346268283113 0.00247816726992228 2962/2960/2959/2957/5430 5 Dengue_virus_type_3 R-HSA-2262752 Cellular responses to stress 13/106 479/10654 9.057175580625575e-4 0.004251840758682562 0.002683607579444615 2353/2908/3576/3456/3552/3320/533/3725/4790/1387/3569/2033/5970 13 Dengue_virus_type_3 R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 3/106 20/10654 9.648384221695954e-4 0.004487826422385182 0.0028325531660024815 8850/1387/2033 3 Dengue_virus_type_4 R-HSA-500792 GPCR ligand binding 314/980 468/10654 8.903904627238285e-226 9.954565373252402e-223 6.0359100841489e-223 1910/2918/2788/729230/6364/151/2532/57007/10316/10803/4987/51289/10681/8843/5367/257313/80834/5368/10563/6754/146/5028/2913/134/6915/64106/1908/8862/4544/5021/719/5540/4988/2847/259292/2864/6865/1901/51764/6363/3356/259294/6373/4543/6370/84109/2922/5031/58191/57121/2149/2150/8620/10663/94235/2917/6870/6347/2833/23620/1268/9290/128674/11255/117579/3060/4889/885/3357/2793/50831/5030/259290/3814/5697/4922/9170/1880/10800/2797/9283/10911/5731/727/301/351/8811/6755/2865/11251/2912/8477/7852/187/6866/1524/5032/84432/2642/5733/9294/3576/256933/54331/4923/7200/2863/1132/3352/2359/8484/56670/1814/10874/5196/6360/50839/83756/10161/80835/50833/1129/3827/347148/150/2798/2846/6357/1909/5173/2828/56923/5737/94233/2832/1128/338557/2693/643/338398/3062/10850/56413/84634/147/51083/6356/2357/2785/552/6750/3355/1907/283869/4985/338442/2925/259296/27199/2783/2920/624/3061/2641/3351/5726/2826/2796/3579/8698/2784/259289/56477/5660/59345/148/55970/50835/6375/2829/4986/2921/4852/23566/1236/1815/2587/5029/2782/1233/2853/6352/6351/1325/222545/57105/53829/1133/29933/6288/2358/1232/140/2867/9934/2151/6751/6376/2916/6869/387129/259295/6372/165140/5020/27198/7201/64805/50840/3269/4935/4295/6863/1902/4828/259286/3350/6752/259293/6366/1131/6374/5443/551/185/1237/129521/6348/8111/1234/1241/50837/9002/2791/5539/887/9568/4829/259287/1903/2786/186/1269/6354/2915/3627/53637/2792/50834/2147/2852/59340/60675/2550/680/1813/886/339403/5724/54429/7976/50865/4887/84539/2861/259285/50836/1230/6846/10886/728/50838/50832/5179/2911/2840/2831/3354/3361/2862/6346/6753/27334/152/846/1906/3358/553/2914/4886/2841/2790/183/10022/5473/718/2787/4283/2837/2919/6387/3577/623/594857 314 Dengue_virus_type_4 R-HSA-373076 Class A/1 (Rhodopsin-like receptors) 256/980 335/10654 6.880339549913715e-205 3.8461098084017667e-202 2.3320729842865437e-202 1910/729230/6364/151/2532/57007/10316/10803/4987/51289/8843/5367/257313/5368/10563/6754/146/5028/134/6915/64106/1908/8862/4544/5021/719/5540/4988/2847/2864/6865/1901/6363/3356/6373/4543/6370/84109/2922/5031/58191/57121/2149/2150/8620/10663/6870/6347/2833/23620/1268/9290/128674/11255/117579/3060/4889/885/3357/5030/3814/5697/4922/9170/1880/10800/2797/9283/10911/5731/727/301/351/8811/6755/2865/11251/8477/7852/187/6866/1524/5032/84432/5733/9294/3576/256933/4923/7200/2863/1132/3352/2359/8484/56670/1814/10874/5196/6360/10161/1129/3827/347148/150/2798/2846/6357/1909/5173/2828/56923/5737/94233/2832/1128/338557/2693/643/3062/10850/56413/84634/147/51083/6356/2357/552/6750/3355/1907/283869/4985/338442/2925/27199/2920/624/3061/3351/2826/2796/3579/8698/56477/5660/148/6375/2829/4986/2921/4852/23566/1236/1815/2587/5029/1233/2853/6352/6351/1325/57105/53829/1133/29933/6288/2358/1232/140/2867/9934/2151/6751/6376/6869/387129/6372/165140/5020/27198/7201/64805/3269/4935/4295/6863/1902/4828/3350/6752/6366/1131/6374/5443/551/185/1237/129521/6348/8111/1234/1241/9002/5539/887/4829/1903/186/1269/6354/3627/53637/2147/2852/59340/60675/680/1813/886/339403/5724/50865/4887/84539/2861/1230/6846/10886/728/5179/2840/2831/3354/3361/2862/6346/6753/27334/152/1906/3358/553/4886/2841/183/10022/5473/718/4283/2837/2919/6387/3577/623/594857 256 Dengue_virus_type_4 R-HSA-418594 G alpha (i) signalling events 239/980 406/10654 2.4257592516904996e-148 9.039996144633262e-146 5.4813647652234455e-146 2918/2788/729230/6364/151/57007/10316/10803/4987/51289/10681/8843/5367/80834/5368/10563/6754/1385/2913/134/8862/4544/719/5540/4988/2847/259292/1901/51764/6363/259294/6373/4543/6370/112/126006/58191/57121/10663/94235/2917/2833/1268/9290/11255/114/117579/4889/2793/50831/5518/5030/5330/259290/5697/9170/1880/26086/9283/727/301/351/6383/8811/6755/11251/2912/6382/7852/187/1524/5588/108/5733/23236/9294/3576/256933/54331/1132/3352/2359/8484/56670/1814/10874/5196/6360/50839/83756/80835/50833/1129/29899/3827/150/113/6357/5173/56923/2832/196883/643/338398/10850/51083/2357/2785/5331/6750/3355/9672/115/283869/4985/338442/259296/27199/2783/2920/624/3351/5726/2826/3579/8698/2784/259289/56477/5660/59345/55970/63940/50835/4986/2921/4852/801/23566/1236/1815/2587/2782/1233/2853/6352/6351/1325/53829/1020/6288/2358/1232/140/9934/6751/6376/2916/259295/6372/165140/27198/64805/50840/2770/111/107/1902/259286/3350/6752/259293/6366/6374/5443/1237/129521/1234/50837/2791/5539/9568/259287/1903/2786/186/109/1269/3627/53637/2792/50834/2852/59340/2550/339403/54429/50865/346562/4887/84539/2861/259285/5578/2771/50836/1230/2773/6714/728/5594/50838/50832/5179/2840/2831/3354/5332/3361/6346/6753/152/846/2914/4886/2841/2790/183/10022/5515/5473/718/2787/4283/2919/6387/3577/5580/623 239 Dengue_virus_type_4 R-HSA-375276 Peptide ligand-binding receptors 169/980 201/10654 6.295968638707451e-146 1.7597232345187324e-143 1.0670010008756838e-143 1910/729230/6364/2532/57007/10316/10803/4987/51289/5367/257313/5368/10563/6754/64106/1908/8862/5021/719/5540/4988/2847/6865/6363/6373/6370/84109/2922/58191/2149/2150/8620/10663/6870/6347/2833/23620/128674/117579/3060/4889/885/3814/5697/4922/9283/10911/727/301/351/8811/6755/7852/187/6866/1524/84432/3576/256933/4923/7200/2359/8484/10874/5196/6360/3827/347148/6357/1909/5173/56923/2832/2693/643/3062/10850/84634/51083/6356/2357/552/6750/1907/283869/4985/2925/2920/624/3061/2826/3579/56477/5660/6375/2829/4986/2921/4852/1236/2587/1233/6352/6351/1325/6288/2358/1232/2151/6751/6376/6869/387129/6372/5020/7201/4295/6863/4828/6752/6366/6374/5443/551/185/1237/129521/6348/1234/9002/5539/887/4829/186/6354/3627/2147/2852/60675/680/886/339403/50865/4887/84539/2861/1230/6846/10886/728/5179/2831/2862/6346/6753/1906/553/4886/183/10022/5473/718/4283/2837/2919/6387/3577/623/594857 169 Dengue_virus_type_4 R-HSA-416476 G alpha (q) signalling events 170/980 217/10654 1.2037482267514712e-136 2.6915810350162897e-134 1.632029174795679e-134 1910/5295/2788/10316/10681/5367/257313/1385/146/5028/6915/8503/64106/1908/5021/2847/2864/6865/51764/3356/84109/2922/5031/57121/2149/2150/8620/94235/6870/23620/128674/3060/885/3357/2793/5330/3814/4922/9170/10800/2797/1839/10911/5731/301/351/4893/2865/1956/8477/6866/5032/84432/5588/5290/2642/23236/54331/4923/7200/2863/5296/5581/10874/2769/10161/3827/347148/2798/2846/1909/2828/56923/5737/3845/94233/1128/338557/2693/3062/56413/84634/147/2785/5331/552/1907/2925/3265/2783/624/3061/2641/2796/2784/59345/148/55970/6375/2829/23566/5029/2782/222545/57105/1133/9630/8525/29933/6288/2358/2867/2151/6869/387129/5020/4314/7201/3269/4935/4295/6863/1902/4828/2776/1131/551/185/129521/8111/695/1241/9002/2791/887/4829/2786/2767/2915/2792/2147/60675/680/886/5724/84539/5578/6846/10886/5594/2911/2840/5332/6654/2862/27334/846/1906/2885/3358/5595/553/2790/2520/183/2787/2837/5580/623/594857 170 Dengue_virus_type_4 R-HSA-199418 Negative regulation of the PI3K/AKT network 89/980 110/10654 4.1727319005603704e-73 7.77519044137749e-71 4.714454989405051e-71 5295/7409/51135/2248/930/3082/8660/2246/79837/8503/8817/941/2251/2261/5154/23396/3932/3643/2064/5293/5159/5518/5155/8395/1839/2252/1956/685/4254/2247/5305/5290/118788/2260/5296/4615/2255/29851/3667/5880/10000/145957/3084/8823/2534/8394/9965/2100/2549/2254/90865/5291/391/5728/152831/2065/1950/2264/3815/5781/3630/2263/2066/4233/27006/207/942/50852/3654/7189/2249/26281/6714/2099/5594/208/5156/2069/940/10818/9542/5879/2885/5595/5515/10718/3556/8396/8074 89 Dengue_virus_type_4 R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 86/980 103/10654 5.955867328191402e-73 9.51237096131141e-71 5.767787307301147e-71 5295/7409/51135/2248/930/3082/8660/2246/79837/8503/8817/941/2251/2261/5154/23396/3932/3643/2064/5293/5159/5518/5155/8395/1839/2252/1956/685/4254/2247/5305/5290/118788/2260/5296/4615/2255/29851/3667/5880/145957/3084/8823/2534/8394/9965/2100/2549/2254/90865/5291/391/152831/2065/1950/2264/3815/5781/3630/2263/2066/4233/27006/207/942/50852/3654/7189/2249/26281/6714/2099/5594/5156/2069/940/10818/9542/5879/2885/5595/5515/10718/3556/8396/8074 86 Dengue_virus_type_4 R-HSA-449147 Signaling by Interleukins 168/980 461/10654 2.7874086087993455e-61 3.8954035307970855e-59 2.3619620316668142e-59 149233/5295/729230/6364/7409/51135/5908/3082/8660/3605/3557/1385/7124/2353/5743/8503/604/282618/3594/53832/7132/4988/834/1901/6363/3568/3552/1432/941/3725/5777/9846/6347/867/3932/4318/7076/4312/5293/3567/5518/3383/3558/4067/1386/301/3562/3717/351/29760/3635/11009/6382/6464/4088/3592/9235/3636/1438/2247/598/5290/3576/5296/4615/7534/3566/1437/3667/3320/3588/4790/51561/3662/4843/2335/5599/2534/5600/6597/375/2309/3688/3656/1436/4313/3600/6356/2357/90865/5291/5604/3565/4985/1399/3561/2920/11213/3559/3560/3574/3551/6773/6352/7412/6351/3458/3578/7297/5781/6288/84868/998/6774/4314/3569/920/7157/5970/4792/3162/356/3593/3055/5443/6850/5803/6348/207/1234/942/59307/5292/3718/1440/3627/3654/3586/9021/7422/29110/3563/3606/7189/5724/3554/3553/163702/6772/1230/1439/5594/8651/8878/6654/4609/3596/2885/54472/7525/5595/1398/5515/3146/2919/3598/3556/3716 168 Dengue_virus_type_4 R-HSA-2219528 PI3K/AKT Signaling in Cancer 78/980 101/10654 3.5757922400085964e-61 4.200786939535672e-59 2.5471300151219036e-59 2475/5295/7249/7409/2248/930/3082/8660/2246/1385/8503/5170/8817/941/2932/2251/2261/5154/3932/2064/5293/5159/5155/1839/2252/1956/685/4254/2247/5290/118788/2260/5296/2255/29851/3667/5880/10000/145957/3084/8823/2534/9965/2100/2309/2549/2254/5291/391/5728/152831/2065/1950/842/2264/3815/5781/2263/2066/4233/27006/207/942/50852/2249/26281/6714/2099/208/5156/2069/940/10818/9542/5879/2885/10718/8074 78 Dengue_virus_type_4 R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 67/980 75/10654 3.7574122893879005e-61 4.200786939535672e-59 2.5471300151219036e-59 5295/7409/2248/930/3082/8660/2246/8503/8817/941/2251/2261/5154/3932/2064/5293/5159/5155/1839/2252/1956/685/4254/2247/5290/118788/2260/5296/2255/29851/3667/5880/145957/3084/8823/2534/9965/2100/2549/2254/5291/391/152831/2065/1950/2264/3815/5781/2263/2066/4233/27006/942/50852/2249/26281/6714/2099/5156/2069/940/10818/9542/5879/2885/10718/8074 67 Dengue_virus_type_4 R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 166/980 473/10654 8.627596486401162e-58 8.768775337996817e-56 5.31691113611708e-56 2324/2475/5295/54106/7409/2962/2248/5908/3082/284217/8660/2246/1385/3685/1003/8503/5228/5170/8817/1432/4908/5777/5906/2251/9846/2261/627/5154/867/3932/10451/4318/3643/3479/2064/5159/1759/5518/382/5155/9402/1213/5590/1839/4067/3717/3791/3918/4893/387/2252/6464/1956/4909/2321/685/60/4254/2247/5290/4914/2260/5296/5581/2255/3912/3667/10000/145957/3320/9564/3084/5335/2335/3845/8823/2534/558/5241/5579/3690/5600/9965/2549/3688/5770/2254/4915/5291/1495/1499/5604/3728/673/152831/4803/1500/2065/3265/1399/1950/5747/8471/4690/1445/801/5140/9047/1111/2264/3815/1020/533/5781/3630/30849/10006/998/6774/7424/2263/5430/8877/5289/2066/4233/23769/3480/27006/11033/207/11140/7422/2249/5578/6772/26281/4916/6714/2099/5594/208/8651/5156/5829/5605/2069/6654/10818/9542/30011/5879/2885/7525/5595/1398/5515/2322/10718/7074/7410/6387/5580/2242/8074/5607 166 Dengue_virus_type_4 R-HSA-76002 Platelet activation, signaling and aggregation 120/980 262/10654 3.6137344178475115e-56 3.366795899294598e-54 2.0414429518366645e-54 5295/2788/88/151/7409/10681/409/5908/3082/5028/6915/8503/7414/51764/4352/5170/146850/1432/2149/94235/5777/5906/5154/27040/3932/10451/7076/6403/3479/2793/5155/5590/4067/23533/351/387/6464/5588/5290/54331/5296/5581/1893/7534/5196/81/2769/5880/3827/9564/150/2335/5294/1/2534/5579/3690/408/5770/2785/5291/391/213/2783/1950/5747/2784/5660/59345/55970/1445/801/2782/87/9630/8525/5781/2151/998/3937/7424/64805/2770/2776/5336/6850/5175/5894/207/9002/2791/3674/2786/2767/7094/2207/2792/2147/7422/346562/5578/2771/2773/6714/5594/6654/152/5879/2885/5595/1398/2790/5054/5473/2787/51206/7410/7066/5580/10672 120 Dengue_virus_type_4 R-HSA-9607240 FLT3 Signaling 116/980 267/10654 2.84483119534193e-51 2.4465548279940596e-49 1.4834585342511764e-49 5295/88/54106/409/2248/5908/3082/8660/2246/7414/3568/5170/8817/64096/5906/2251/9846/2261/5154/27040/2064/5159/3567/5518/5155/1839/3558/2674/3562/9048/3717/4893/2252/6464/1956/685/4902/60/4254/1438/2247/5290/2260/5296/2255/1437/3667/145957/3084/2335/3845/8823/2534/3690/408/9965/2549/5623/2254/5291/5604/673/152831/2065/3265/3561/1950/3559/3560/5747/369/2676/1445/801/5140/2264/3815/5781/30849/2263/5289/2066/4233/3055/27006/5894/3674/7094/3718/2668/3563/5979/2249/25780/7010/26281/1439/6714/5594/208/5156/5605/2069/6654/10818/9542/1739/2885/5595/5515/284/2322/10718/2675/3716/8074 116 Dengue_virus_type_4 R-HSA-5663202 Diseases of signal transduction 136/980 377/10654 1.1715202362675427e-48 9.35542588676509e-47 5.672624301927049e-47 2475/5295/7249/7409/2962/409/2248/5908/930/3082/8660/2246/1385/7048/8850/8503/7414/399687/5170/8817/941/2932/5906/2251/9846/2261/5154/867/10013/1387/3932/2064/5293/5159/5518/5155/8805/1839/3717/4893/2252/11052/6464/1956/26127/4088/11160/685/60/4254/2247/5290/118788/2260/5296/2255/29851/3667/5880/10000/145957/3320/3084/9208/5335/2335/3845/8823/2534/2033/3690/408/9965/2100/2309/2549/2254/5291/391/1499/5604/55294/5728/673/152831/2065/3265/1950/369/842/1445/801/2264/3815/5781/3065/6774/4851/2263/5430/2066/4233/27006/5894/207/4087/3674/942/50852/7750/7094/11140/2249/6772/26281/6714/2099/5594/208/5156/5605/2069/9530/6654/940/4609/10818/9542/1523/5879/2885/613/5595/5515/10718/8074 136 Dengue_virus_type_4 R-HSA-9006925 Intracellular signaling by second messengers 117/980 305/10654 6.12480005956709e-45 4.5650176443973375e-43 2.7679798163938286e-43 2475/5295/7249/7409/51135/2248/930/3082/8660/2246/79837/1385/8503/1958/112/5170/8817/941/3725/2932/2251/2261/5154/23396/3932/114/3643/2064/5293/5159/5518/5155/8395/1839/1386/2252/1956/685/4254/2247/5305/5290/108/118788/2260/5296/5581/4615/2255/29851/3667/5880/10000/145957/3084/113/5335/8823/2534/196883/8394/9965/2100/2309/2549/2254/90865/5291/115/391/5728/152831/2065/1950/842/801/6615/2264/3815/5781/3630/3065/2263/7157/111/107/2066/4233/57521/27006/207/942/50852/109/3654/7189/2249/5578/26281/6714/2099/5594/208/5156/2069/940/10818/9542/5879/2885/5595/5515/10718/5580/3556/8396/8074 117 Dengue_virus_type_4 R-HSA-5684996 MAPK1/MAPK3 signaling 105/980 255/10654 1.0338078692680341e-43 7.223732486510389e-42 4.380080709267198e-42 88/409/2248/5908/3082/8660/2246/7414/3568/8817/64096/5906/2251/2261/5154/27040/2064/5159/3567/5518/5155/1839/3558/2674/3562/9048/3717/4893/2252/6464/1956/685/4902/60/4254/1438/2247/2260/2255/1437/3667/145957/3084/2335/3845/8823/2534/3690/408/9965/5623/2254/5604/673/152831/2065/3265/3561/1950/3559/3560/5747/369/2676/1445/801/2264/3815/7297/5781/3569/2263/2066/4233/27006/5894/3674/7094/3718/2668/3563/5979/2249/25780/7010/26281/1439/6714/5594/5156/5605/2069/6654/10818/9542/1739/2885/5595/5515/284/2322/10718/2675/3716/8074 105 Dengue_virus_type_4 R-HSA-380108 Chemokine receptors bind chemokines 50/980 59/10654 2.6985305452789567e-43 1.774680676248161e-41 1.0760703846189773e-41 729230/6364/57007/10803/10563/6363/6373/6370/58191/10663/6347/2833/7852/1524/3576/5196/6360/6357/643/10850/6356/2920/2826/3579/56477/6375/2829/2921/1236/1233/6352/6351/1232/6376/6372/6366/6374/1237/6348/1234/6354/3627/1230/6846/6346/5473/4283/2919/6387/3577 50 Dengue_virus_type_4 R-HSA-5673001 RAF/MAP kinase cascade 102/980 249/10654 3.231298420552399e-42 2.006995352320879e-40 1.2169334402548218e-40 88/409/2248/5908/3082/8660/2246/7414/3568/8817/64096/5906/2251/2261/5154/27040/2064/5159/3567/5518/5155/1839/3558/2674/3562/9048/3717/4893/2252/6464/1956/685/4902/60/4254/1438/2247/2260/2255/1437/3667/145957/3084/2335/3845/8823/2534/3690/408/9965/5623/2254/5604/673/152831/2065/3265/3561/1950/3559/3560/5747/369/2676/1445/801/2264/3815/2263/2066/4233/27006/5894/3674/7094/3718/2668/3563/5979/2249/25780/7010/26281/1439/6714/5594/5156/5605/2069/6654/10818/9542/1739/2885/5595/5515/284/2322/10718/2675/3716/8074 102 Dengue_virus_type_4 R-HSA-9009391 Extra-nuclear estrogen signaling 56/980 77/10654 1.3169518756210647e-41 7.749222089180791e-40 4.6987091850413616e-40 5295/2788/10681/1385/2353/8503/51764/5170/94235/4318/2793/5590/1839/4893/6464/1956/685/5290/54331/5296/10000/3320/3845/2100/2309/4313/2785/3265/2783/1950/5747/2784/59345/55970/801/2782/4314/2770/8877/3480/207/2791/1903/2786/2792/346562/2771/2773/6714/2099/5594/208/2069/5595/2790/2787 56 Dengue_virus_type_4 R-HSA-5683057 MAPK family signaling cascades 110/980 294/10654 5.186318316634165e-41 2.899151938998498e-39 1.7578889452170536e-39 88/409/2248/5908/3082/8660/2246/7414/3568/8817/64096/3725/5906/2251/2261/5154/27040/2064/5159/3567/5518/5155/1839/3558/2674/3562/9048/3717/4893/2252/6464/1956/685/4902/60/4254/1438/2247/2260/2255/1437/3667/145957/3084/2335/3845/8823/2534/3690/408/9965/2309/5623/2254/5604/673/152831/2065/3265/3561/1950/3559/3560/5747/369/2676/1445/801/2264/3815/7297/5781/998/3569/2263/2066/4233/27006/5894/3674/7094/3718/2668/3563/5979/2249/25780/7010/26281/1439/6714/5594/5156/5605/2069/6654/4609/10818/9542/5879/1739/2885/5595/5515/284/2322/10718/2675/3716/8074 110 Dengue_virus_type_4 R-HSA-420499 Class C/3 (Metabotropic glutamate/pheromone receptors) 38/980 38/10654 2.158776347110046e-40 1.1492914076519197e-38 6.968681541548219e-39 2918/80834/2913/259292/259294/2917/50831/259290/2912/50839/83756/80835/50833/338398/259296/5726/259289/50835/222545/2916/259295/50840/259286/259293/50837/9568/259287/2915/50834/2550/54429/259285/50836/50838/50832/2911/846/2914 38 Dengue_virus_type_4 R-HSA-1257604 PIP3 activates AKT signaling 103/980 264/10654 2.499048371156516e-40 1.2699709449786295e-38 7.700416990549265e-39 2475/5295/7249/7409/51135/2248/930/3082/8660/2246/79837/1385/8503/1958/5170/8817/941/3725/2932/2251/2261/5154/23396/3932/3643/2064/5293/5159/5518/5155/8395/1839/1386/2252/1956/685/4254/2247/5305/5290/118788/2260/5296/4615/2255/29851/3667/5880/10000/145957/3084/8823/2534/8394/9965/2100/2309/2549/2254/90865/5291/391/5728/152831/2065/1950/842/6615/2264/3815/5781/3630/3065/2263/7157/2066/4233/57521/27006/207/942/50852/3654/7189/2249/26281/6714/2099/5594/208/5156/2069/940/10818/9542/5879/2885/5595/5515/10718/3556/8396/8074 103 Dengue_virus_type_4 R-HSA-74751 Insulin receptor signalling cascade 46/980 54/10654 4.085185442398758e-40 1.9857553585225268e-38 1.2040546567070025e-38 5295/54106/2248/8660/2246/5170/8817/2251/9846/2261/3643/4893/2252/6464/2247/5290/2260/5296/2255/3667/3845/8823/9965/2549/2254/5291/152831/3265/5140/2264/5781/3630/30849/2263/5289/27006/2249/26281/5594/208/6654/10818/2885/5595/2322/8074 46 Dengue_virus_type_4 R-HSA-2428924 IGF1R signaling cascade 45/980 53/10654 3.947081040756774e-39 1.8386819181525307e-37 1.1148772764242817e-37 5295/54106/2248/8660/2246/5170/8817/2251/9846/2261/3479/4893/2252/6464/2247/5290/2260/5296/2255/3667/3845/8823/9965/2549/2254/5291/152831/3265/8471/5140/2264/5781/30849/2263/5289/3480/27006/2249/26281/208/6654/10818/2885/2322/8074 45 Dengue_virus_type_4 R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 45/980 54/10654 2.1639893523341523e-38 9.677360383638329e-37 5.8678279701187116e-37 5295/54106/2248/8660/2246/5170/8817/2251/9846/2261/3479/4893/2252/6464/2247/5290/2260/5296/2255/3667/3845/8823/9965/2549/2254/5291/152831/3265/8471/5140/2264/5781/30849/2263/5289/3480/27006/2249/26281/208/6654/10818/2885/2322/8074 45 Dengue_virus_type_4 R-HSA-2428928 IRS-related events triggered by IGF1R 44/980 52/10654 3.7974930301983696e-38 1.632922002985299e-36 9.90115591679251e-37 5295/54106/2248/8660/2246/5170/8817/2251/9846/2261/3479/4893/2252/2247/5290/2260/5296/2255/3667/3845/8823/9965/2549/2254/5291/152831/3265/8471/5140/2264/5781/30849/2263/5289/3480/27006/2249/26281/208/6654/10818/2885/2322/8074 44 Dengue_virus_type_4 R-HSA-112399 IRS-mediated signalling 41/980 48/10654 5.883365674601909e-36 2.4361491941499754e-34 1.4771491206407911e-34 5295/54106/2248/8660/2246/5170/8817/2251/9846/2261/4893/2252/2247/5290/2260/5296/2255/3667/3845/8823/9965/2549/2254/5291/152831/3265/5140/2264/5781/30849/2263/5289/27006/2249/26281/208/6654/10818/2885/2322/8074 41 Dengue_virus_type_4 R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 60/980 108/10654 2.177640701130184e-34 8.695008228084092e-33 5.2721827501046565e-33 149233/5295/3082/3605/7124/2353/5743/604/4988/1901/3552/6347/4318/7076/4312/3383/301/3717/3592/2247/598/3576/3566/3320/51561/3662/4843/2335/2309/3688/4313/6356/3565/4985/3561/7412/7297/6288/6774/4314/3569/7157/3162/356/3593/5443/207/5292/3718/3586/9021/7422/3606/3553/6772/8651/4609/3596/3598/3716 60 Dengue_virus_type_4 R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 39/980 48/10654 1.423899563145087e-32 5.48937831584899e-31 3.3284621367166467e-31 5295/7409/8503/3568/5777/9846/867/5293/3567/3558/4067/3562/3717/29760/3635/6464/3636/1438/5290/5296/7534/1437/2534/5291/1399/3561/3559/3560/5781/3055/6850/3718/3563/1439/6654/2885/7525/1398/3716 39 Dengue_virus_type_4 R-HSA-109704 PI3K Cascade 37/980 44/10654 4.944541615792049e-32 1.8426658421518368e-30 1.1172929124807296e-30 5295/54106/2248/8660/2246/5170/8817/2251/9846/2261/2252/2247/5290/2260/5296/2255/3667/8823/9965/2549/2254/5291/152831/5140/2264/5781/30849/2263/5289/27006/2249/26281/208/10818/2885/2322/8074 37 Dengue_virus_type_4 R-HSA-392518 Signal amplification 31/980 32/10654 1.4180327259625353e-31 4.954251836331608e-30 3.0039903799995816e-30 2788/10681/5028/6915/51764/1432/94235/2793/54331/2769/2785/2783/2784/59345/55970/2782/9630/64805/2770/2776/2791/2786/2767/2792/346562/2771/2773/6714/2790/2787/10672 31 Dengue_virus_type_4 R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 31/980 32/10654 1.4180327259625353e-31 4.954251836331608e-30 3.0039903799995816e-30 2788/10681/409/51764/2149/94235/2793/54331/2769/408/2785/2783/2784/59345/55970/2782/9630/2151/2776/9002/2791/2786/2767/2792/2147/6714/5594/5595/2790/2787/10672 31 Dengue_virus_type_4 R-HSA-418597 G alpha (z) signalling events 38/980 48/10654 5.715598539379444e-31 1.93637550515946e-29 1.1741133841659847e-29 2788/151/10681/51764/112/94235/114/2793/5588/108/54331/5581/150/113/196883/5579/2785/115/2783/2784/59345/55970/2782/2770/111/107/2791/2786/109/2792/346562/5578/2771/2773/152/2790/2787/5580 38 Dengue_virus_type_4 R-HSA-6783783 Interleukin-10 signaling 37/980 47/10654 5.0931676092757935e-30 1.6747533491677461e-28 1.0154798577008085e-28 729230/6364/3557/7124/5743/7132/6363/3552/941/6347/7076/3383/3592/3576/1437/3588/2357/2920/6352/6351/7297/6774/3569/3593/6348/1234/942/1440/3627/3586/3606/5724/3554/3553/1230/2919/3716 37 Dengue_virus_type_4 R-HSA-397795 G-protein beta:gamma signalling 30/980 32/10654 2.2453172028609718e-29 7.1721846651387615e-28 4.34882489817283e-28 2788/10681/51764/5170/146850/94235/2793/5330/23533/387/23236/54331/10000/5294/2785/5331/2783/2784/59345/55970/2782/998/207/695/2791/2786/2792/208/2790/2787 30 Dengue_virus_type_4 R-HSA-74752 Signaling by Insulin receptor 47/980 78/10654 2.3155916859731136e-29 7.191198624772058e-28 4.360353934990308e-28 5295/54106/2248/8660/2246/5170/8817/2251/9846/2261/3643/4893/2252/6464/2247/5290/2260/5296/2255/3667/3845/8823/9965/2549/2254/5291/152831/3265/5140/2264/533/5781/3630/30849/2263/5289/27006/2249/26281/5594/208/6654/10818/2885/5595/2322/8074 47 Dengue_virus_type_4 R-HSA-1226099 Signaling by FGFR in disease 42/980 63/10654 5.513750742777945e-29 1.6660468460610116e-27 1.0102007050779507e-27 5295/2962/2248/2246/399687/8817/2251/9846/2261/8805/4893/2252/11052/26127/11160/2247/5290/2260/2255/9208/5335/3845/8823/2549/2254/3265/2264/6774/2263/5430/27006/7750/2249/6772/26281/9530/6654/10818/1523/2885/613/8074 42 Dengue_virus_type_4 R-HSA-912526 Interleukin receptor SHC signaling 27/980 27/10654 7.544171894335715e-29 2.2195747836492972e-27 1.3458301107900834e-27 5295/8503/3568/5777/9846/5293/3567/3558/3562/3717/3635/6464/3636/1438/5290/5296/1437/5291/3561/3559/3560/3718/3563/1439/6654/2885/3716 27 Dengue_virus_type_4 R-HSA-2424491 DAP12 signaling 28/980 30/10654 2.455833773536328e-27 7.040056817470807e-26 4.268709717024009e-26 5295/3824/3133/27040/3932/10451/9402/4893/6464/5290/5296/5335/3845/2534/7305/5291/3265/54209/3822/3937/5336/567/6850/695/6654/5879/2885/7410 28 Dengue_virus_type_4 R-HSA-451927 Interleukin-2 family signaling 34/980 44/10654 3.461261281085617e-27 9.674225280634299e-26 5.865927013208258e-26 5295/8503/3568/5777/9846/3932/5293/3567/3558/3562/3717/3635/6464/3636/1438/5290/5296/1437/3600/5291/3561/3559/3560/3578/84868/6774/6850/3718/3563/6772/1439/6654/2885/3716 34 Dengue_virus_type_4 R-HSA-392451 G beta:gamma signalling through PI3Kgamma 25/980 25/10654 9.35413819545911e-27 2.55071378110324e-25 1.5466148903403508e-25 2788/10681/51764/5170/146850/94235/2793/23533/387/54331/10000/5294/2785/2783/2784/59345/55970/2782/207/2791/2786/2792/208/2790/2787 25 Dengue_virus_type_4 R-HSA-194138 Signaling by VEGF 52/980 107/10654 3.15602484297551e-26 8.401037558206238e-25 5.0939348342762615e-25 2324/2475/5295/7409/3685/1003/5228/5170/1432/10451/5590/3791/4893/387/2321/60/5290/5296/10000/3320/9564/5335/3845/2534/558/5579/3690/5600/5291/1495/1499/3728/1500/3265/5747/4690/801/9047/10006/998/7424/8877/207/7422/5578/6714/208/5829/5879/1398/7410/5580 52 Dengue_virus_type_4 R-HSA-5655302 Signaling by FGFR1 in disease 31/980 38/10654 3.2488968875968726e-26 8.447131907751868e-25 5.121883954987481e-25 5295/2246/399687/2251/9846/8805/4893/11052/26127/11160/2247/5290/2260/9208/5335/3845/2549/2254/3265/6774/7750/2249/6772/26281/9530/6654/10818/1523/2885/613/8074 31 Dengue_virus_type_4 R-HSA-114604 GPVI-mediated activation cascade 29/980 35/10654 5.716356835803068e-25 1.4524743050972343e-23 8.807018665687023e-24 5295/7409/8503/5170/146850/5777/27040/3932/10451/5590/4067/23533/387/5290/5296/5880/5294/2534/5291/391/5781/998/3937/5336/6850/2207/5879/51206/7410 29 Dengue_virus_type_4 R-HSA-428930 Thromboxane signalling through TP receptor 23/980 23/10654 1.155423867240612e-24 2.870586407944454e-23 1.740568352053694e-23 2788/10681/6915/51764/94235/2793/54331/2769/2785/2783/2784/59345/55970/2782/9630/2776/2791/2786/2767/2792/2790/2787/10672 23 Dengue_virus_type_4 R-HSA-5654743 Signaling by FGFR4 31/980 41/10654 2.1997839529453026e-24 5.346431433462713e-23 3.2417868780246567e-23 5295/2246/8817/2251/867/5518/4893/6464/2247/5290/5335/3845/8823/9965/2549/2254/673/152831/3265/2264/5781/2249/26281/6714/5594/6654/10818/2885/5595/5515/8074 31 Dengue_virus_type_4 R-HSA-418592 ADP signalling through P2Y purinoceptor 1 24/980 25/10654 2.375774977705715e-24 5.651311542712743e-23 3.426649687889094e-23 2788/10681/5028/51764/1432/94235/2793/54331/2769/2785/2783/2784/59345/55970/2782/9630/2776/2791/2786/2767/2792/6714/2790/2787 24 Dengue_virus_type_4 R-HSA-4420097 VEGFA-VEGFR2 Pathway 48/980 99/10654 3.056587499867179e-24 7.119301718440639e-23 4.3167595392861037e-23 2475/5295/7409/3685/1003/5170/1432/10451/5590/3791/4893/387/60/5290/5296/10000/3320/9564/5335/3845/2534/558/5579/3690/5600/5291/1495/1499/3728/1500/3265/5747/4690/801/9047/10006/998/8877/207/7422/5578/6714/208/5829/5879/1398/7410/5580 48 Dengue_virus_type_4 R-HSA-1227986 Signaling by ERBB2 34/980 50/10654 3.990044030739187e-24 9.103814747686553e-23 5.5200609147068455e-023 5295/2064/1839/4893/387/6464/1956/685/5290/5581/10000/145957/3320/3084/5335/3845/2534/2549/2065/3265/1950/2066/207/11140/5578/6714/208/2069/6654/9542/2885/7525/10718/5580 34 Dengue_virus_type_4 R-HSA-392170 ADP signalling through P2Y purinoceptor 12 22/980 22/10654 1.2823033983822698e-23 2.8672303987827553e-22 1.738533449596172e-22 2788/10681/51764/94235/2793/54331/2785/2783/2784/59345/55970/2782/64805/2770/2791/2786/2792/346562/2771/2773/2790/2787 22 Dengue_virus_type_4 R-HSA-5654696 Downstream signaling of activated FGFR2 26/980 30/10654 1.6043750919670265e-23 3.517041868272815e-22 2.132543981892188e-22 5295/2248/2246/8817/2251/4893/2252/6464/2247/5290/2255/5335/3845/8823/2549/2254/3265/5781/2263/27006/2249/26281/6654/10818/2885/8074 26 Dengue_virus_type_4 R-HSA-1433557 Signaling by SCF-KIT 31/980 43/10654 2.5113307674473026e-23 5.399361150011701e-22 3.2738805956195605e-22 5295/7409/8503/5777/9846/867/3932/4318/9402/4067/3717/4893/4254/5290/5296/3845/2534/3265/1111/3815/5781/6774/5578/6772/6714/8651/6654/5879/2885/7525/2242 31 Dengue_virus_type_4 R-HSA-8939211 ESR-mediated signaling 73/980 223/10654 2.9214665954221984e-23 6.130976769842296e-22 3.7174927405879284e-22 5295/2788/2962/10681/1385/1025/2353/8850/8503/51764/5170/3725/94235/1387/4318/2793/5590/1839/1386/4893/6464/1956/685/5290/54331/5296/10000/3320/3845/2033/5241/2100/2309/4313/2785/3265/2783/1950/5747/2784/59345/55970/1105/801/2782/1655/3065/4314/5430/2770/8877/2066/3480/207/2791/1903/2786/6667/2792/346562/2771/2773/6714/2099/5594/208/2069/2957/4609/5595/2790/2787/6387 73 Dengue_virus_type_4 R-HSA-111885 Opioid Signalling 45/980 91/10654 2.9612946831080857e-23 6.130976769842296e-22 3.7174927405879284e-22 2788/10681/1385/4988/51764/112/94235/114/2793/5518/5330/108/23236/54331/113/5173/196883/2785/5331/115/2783/2784/59345/55970/801/2782/1020/2770/111/107/5443/2791/2786/109/2792/346562/5578/2771/2773/5594/5332/2790/5515/2787/5580 45 Dengue_virus_type_4 R-HSA-163685 Integration of energy metabolism 49/980 108/10654 4.238842324981392e-23 8.616410398780358e-22 5.2245252771062525e-22 2788/10681/2864/51764/112/5563/94235/5906/114/2793/5518/5330/108/2642/23236/54331/2769/150/113/6794/196883/2785/5331/115/2783/2641/2784/59345/55970/2782/9630/3630/2770/111/107/2776/1131/2791/2786/2767/109/2792/5578/2771/152/2790/5515/9370/2787 49 Dengue_virus_type_4 R-HSA-5654716 Downstream signaling of activated FGFR4 24/980 27/10654 2.3204437372262602e-022 4.632600175390998e-21 2.8089582082212624e-21 5295/2246/8817/2251/4893/6464/2247/5290/5335/3845/8823/9965/2549/2254/152831/3265/2264/5781/2249/26281/6654/10818/2885/8074 24 Dengue_virus_type_4 R-HSA-166520 Signaling by NTRKs 46/980 101/10654 7.619102636244527e-22 1.4944134644423476e-20 9.061315046613989e-21 5295/8660/1385/1432/4908/5906/627/1759/5518/1213/4893/387/6464/4909/5290/4914/5296/3667/5335/3845/2534/5600/2549/4915/5291/5604/673/4803/3265/1399/1020/5781/6774/4916/6714/5594/5605/6654/10818/5879/2885/5595/1398/5515/7074/5607 46 Dengue_virus_type_4 R-HSA-202040 G-protein activation 24/980 28/10654 1.4840991200326446e-21 2.8607289934422355e-20 1.7345913490036717e-20 2788/10681/4988/51764/94235/2793/54331/5173/2785/2783/2784/59345/55970/2782/2770/5443/2791/2786/2792/346562/2771/2773/2790/2787 24 Dengue_virus_type_4 R-HSA-5654736 Signaling by FGFR1 32/980 50/10654 1.5338969201876631e-21 2.906604672491199e-20 1.7624078797517484e-20 5295/2248/2246/8817/2251/867/5518/4893/6464/2247/5290/2260/2255/5335/3845/2549/2254/673/3265/5781/23769/27006/2249/26281/6714/5594/6654/10818/2885/5595/5515/8074 32 Dengue_virus_type_4 R-HSA-418217 G beta:gamma signalling through PLC beta 20/980 20/10654 1.5749015951965637e-21 2.9345666390495967e-20 1.779362504046644e-20 2788/10681/51764/94235/2793/5330/23236/54331/2785/5331/2783/2784/59345/55970/2782/2791/2786/2792/2790/2787 20 Dengue_virus_type_4 R-HSA-1250196 SHC1 events in ERBB2 signaling 21/980 22/10654 2.8586005905104087e-21 5.239205672443667e-20 3.176770975476624e-20 2064/1839/4893/6464/1956/685/5581/145957/3084/3845/2065/3265/1950/2066/5578/2069/6654/9542/2885/10718/5580 21 Dengue_virus_type_4 R-HSA-977444 GABA B receptor activation 28/980 39/10654 4.1919844240802105e-21 7.439108866859802e-20 4.51067329842549e-20 2788/112/94235/114/2793/108/54331/113/196883/2785/115/2783/2784/55970/2782/2770/111/107/9568/2786/109/2792/2550/346562/2771/2773/2790/2787 28 Dengue_virus_type_4 R-HSA-991365 Activation of GABAB receptors 28/980 39/10654 4.1919844240802105e-21 7.439108866859802e-20 4.51067329842549e-20 2788/112/94235/114/2793/108/54331/113/196883/2785/115/2783/2784/55970/2782/2770/111/107/9568/2786/109/2792/2550/346562/2771/2773/2790/2787 28 Dengue_virus_type_4 R-HSA-5654741 Signaling by FGFR3 28/980 40/10654 1.2764903410950887e-20 2.229869064600483e-19 1.3520720060283506e-19 5295/2246/8817/2261/867/5518/4893/6464/2247/5290/5335/3845/8823/2549/2254/673/3265/5781/2249/26281/6714/5594/6654/10818/2885/5595/5515/8074 28 Dengue_virus_type_4 R-HSA-2871796 FCERI mediated MAPK activation 25/980 32/10654 1.672862452911201e-20 2.8773234190072657e-19 1.7446533112142728e-19 7409/2353/3725/27040/10451/9402/4067/4893/2206/6464/2205/5335/3845/5599/3265/3937/5336/6850/2207/5594/6654/5879/2885/5595/7410 25 Dengue_virus_type_4 R-HSA-190236 Signaling by FGFR 41/980 87/10654 2.6916247617923538e-20 4.559449217702805e-19 2.7646034235953365e-19 5295/2962/2248/2246/8817/2251/2261/867/5518/4893/2252/6464/2247/5290/2260/2255/5335/3845/8823/9965/2549/2254/673/152831/3265/2264/5781/2263/5430/23769/27006/2249/26281/6714/5594/6654/10818/2885/5595/5515/8074 41 Dengue_virus_type_4 R-HSA-500657 Presynaptic function of Kainate receptors 20/980 21/10654 3.0229402313517604e-20 5.044249520375027e-19 3.0585601083904697e-19 2788/10681/51764/94235/2793/5330/23236/54331/2785/5331/2783/2784/59345/55970/2782/2791/2786/2792/2790/2787 20 Dengue_virus_type_4 R-HSA-163359 Glucagon signaling in metabolic regulation 25/980 33/10654 6.304619251010669e-20 1.0365535768573424e-18 6.2851003059611e-19 2788/51764/112/94235/114/108/2642/54331/113/196883/2785/115/2783/2641/2784/59345/55970/2782/111/107/2791/2786/109/2790/2787 25 Dengue_virus_type_4 R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 23/980 28/10654 7.233181972837157e-20 1.1719851370481075e-18 7.106284043489137e-19 2788/10681/51764/112/94235/2793/54331/150/2785/2783/2784/59345/55970/2782/2770/111/2791/2786/2792/2771/152/2790/2787 23 Dengue_virus_type_4 R-HSA-912694 Regulation of IFNA signaling 22/980 26/10654 1.3368479460049052e-19 2.1351371480478345e-18 1.2946316950784346e-18 3443/5777/3451/3441/3449/3448/3444/3452/5770/3455/3456/6773/3454/7297/5781/9021/3446/6772/3440/8651/3445/3716 22 Dengue_virus_type_4 R-HSA-388841 Costimulation by the CD28 family 36/980 70/10654 1.3743498105223207e-19 2.1641170255830346e-18 1.3122035255394732e-18 2475/5295/7409/8503/3123/5170/941/5777/3932/5518/9402/4067/915/5290/5296/917/29851/10000/919/2534/3122/1445/916/5781/998/920/1493/207/942/6714/208/940/5879/2885/7525/5515 36 Dengue_virus_type_4 R-HSA-1839124 FGFR1 mutant receptor activation 24/980 31/10654 1.4538584395749234e-19 2.2265941581435127e-18 1.3500862798648173e-18 5295/2246/399687/2251/9846/8805/11052/26127/11160/2247/5290/2260/9208/2254/6774/7750/2249/6772/26281/9530/1523/2885/613/8074 24 Dengue_virus_type_4 R-HSA-5654687 Downstream signaling of activated FGFR1 24/980 31/10654 1.4538584395749234e-19 2.2265941581435127e-18 1.3500862798648173e-18 5295/2248/2246/2251/4893/6464/2247/5290/2260/2255/5335/3845/2549/2254/3265/5781/23769/27006/2249/26281/6654/10818/2885/8074 24 Dengue_virus_type_4 R-HSA-8964315 G beta:gamma signalling through BTK 18/980 18/10654 1.92695150963286e-19 2.9112591726615374e-18 1.7652301169325204e-18 2788/10681/51764/94235/2793/54331/2785/2783/2784/59345/55970/2782/695/2791/2786/2792/2790/2787 18 Dengue_virus_type_4 R-HSA-2172127 DAP12 interactions 28/980 43/10654 2.639498690707297e-19 3.882841495014156e-18 2.354345092542243e-18 5295/3824/3133/27040/3932/10451/9402/4893/6464/5290/5296/5335/3845/2534/7305/5291/3265/54209/3822/3937/5336/567/6850/695/6654/5879/2885/7410 28 Dengue_virus_type_4 R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 28/980 43/10654 2.639498690707297e-19 3.882841495014156e-18 2.354345092542243e-18 2788/10681/51764/112/94235/114/2793/108/54331/113/196883/2785/115/2783/8766/2784/59345/55970/2782/111/107/551/2791/2786/109/2792/2790/2787 28 Dengue_virus_type_4 R-HSA-909733 Interferon alpha/beta signaling 35/980 69/10654 7.93933491647054e-19 1.1527501865732551e-17 6.98965370636641e-18 3443/3665/1958/5777/3133/3451/3441/3449/3448/10379/3444/3452/3662/5770/3455/3456/6773/3454/7297/3663/5781/3664/3105/3661/9021/3660/3434/3446/6772/3440/8651/3659/4599/3445/3716 35 Dengue_virus_type_4 R-HSA-5654700 FRS-mediated FGFR2 signaling 21/980 25/10654 1.254746118776377e-18 1.7535077009899867e-17 1.0632322374894564e-17 2248/2246/8817/2251/4893/2252/2247/2255/3845/8823/2254/3265/5781/2263/27006/2249/26281/6654/10818/2885/8074 21 Dengue_virus_type_4 R-HSA-5654708 Downstream signaling of activated FGFR3 21/980 25/10654 1.254746118776377e-18 1.7535077009899867e-17 1.0632322374894564e-17 5295/2246/8817/2261/4893/6464/2247/5290/5335/3845/8823/2549/2254/3265/5781/2249/26281/6654/10818/2885/8074 21 Dengue_virus_type_4 R-HSA-9006115 Signaling by NTRK2 (TRKB) 21/980 25/10654 1.254746118776377e-18 1.7535077009899867e-17 1.0632322374894564e-17 5295/4908/627/4893/6464/4909/5290/5335/3845/2534/2549/4915/3265/1020/5781/6714/6654/10818/5879/2885/7074 21 Dengue_virus_type_4 R-HSA-422356 Regulation of insulin secretion 37/980 78/10654 1.4628913754200772e-18 2.0191513058267236e-17 1.2243041530481218e-17 2788/10681/2864/51764/112/94235/5906/114/2793/5330/23236/54331/2769/150/2785/5331/2783/2641/2784/59345/55970/2782/9630/3630/2770/111/2776/1131/2791/2786/2767/2792/5578/2771/152/2790/2787 37 Dengue_virus_type_4 R-HSA-375280 Amine ligand-binding receptors 27/980 42/10654 1.917625130028396e-18 2.6145181650874958e-17 1.5853024181492773e-17 151/146/3356/11255/3357/1132/3352/1814/1129/150/1128/147/3355/3351/148/1815/1133/3269/4935/3350/1131/59340/1813/3354/3361/152/3358 27 Dengue_virus_type_4 R-HSA-450604 KSRP (KHSRP) binds and destabilizes mRNA 17/980 17/10654 2.128451008096007e-18 2.801436045211197e-17 1.6986393118501187e-17 5393/1432/11340/7534/51010/5600/56915/8570/23404/51013/5073/23016/207/54512/118460/167227/22894 17 Dengue_virus_type_4 R-HSA-5654695 PI-3K cascade:FGFR2 20/980 23/10654 2.129893236520141e-18 2.801436045211197e-17 1.6986393118501187e-17 5295/2248/2246/8817/2251/2252/2247/5290/2255/8823/2549/2254/5781/2263/27006/2249/26281/10818/2885/8074 20 Dengue_virus_type_4 R-HSA-5654699 SHC-mediated cascade:FGFR2 20/980 23/10654 2.129893236520141e-18 2.801436045211197e-17 1.6986393118501187e-17 2248/2246/8817/2251/4893/2252/6464/2247/2255/3845/8823/2254/3265/2263/27006/2249/26281/6654/2885/8074 20 Dengue_virus_type_4 R-HSA-5654727 Negative regulation of FGFR2 signaling 24/980 34/10654 5.530381947883854e-18 7.18949653224901e-17 4.35932187813611e-17 2248/2246/8817/2251/867/5518/2252/2247/2255/8823/2254/673/5781/2263/27006/2249/26281/6714/5594/10818/2885/5595/5515/8074 24 Dengue_virus_type_4 R-HSA-5654738 Signaling by FGFR2 35/980 73/10654 8.150273871731851e-18 1.047357033171978e-16 6.350606622377873e-17 5295/2962/2248/2246/8817/2251/867/5518/4893/2252/6464/2247/5290/2255/5335/3845/8823/2549/2254/673/3265/5781/2263/5430/27006/2249/26281/6714/5594/6654/10818/2885/5595/5515/8074 35 Dengue_virus_type_4 R-HSA-186763 Downstream signal transduction 22/980 29/10654 1.0651477054774768e-17 1.3532217440043399e-16 8.205204812529846e-17 5295/5154/5159/5155/4893/5290/5296/9564/5335/3845/5291/3265/1399/4690/5781/6774/6772/6714/5156/6654/2885/1398 22 Dengue_virus_type_4 R-HSA-8853659 RET signaling 26/980 41/10654 1.3742963316876797e-17 1.7263632571087932e-16 1.0467733147331353e-16 5295/8660/8503/64096/9846/5293/2674/9048/6464/4902/5290/5296/5335/2549/5623/5291/2676/5781/2668/5979/5578/6714/6654/10818/2885/2675 26 Dengue_virus_type_4 R-HSA-5654712 FRS-mediated FGFR4 signaling 19/980 22/10654 2.0505354949298764e-17 2.491846394925654e-16 1.5109208910009617e-16 2246/8817/2251/4893/2247/3845/8823/9965/2254/152831/3265/2264/5781/2249/26281/6654/10818/2885/8074 19 Dengue_virus_type_4 R-HSA-5655332 Signaling by FGFR3 in disease 19/980 22/10654 2.0505354949298764e-17 2.491846394925654e-16 1.5109208910009617e-16 5295/2246/8817/2261/4893/2247/5290/5335/3845/8823/2549/2254/3265/2249/26281/6654/10818/2885/8074 19 Dengue_virus_type_4 R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 19/980 22/10654 2.0505354949298764e-17 2.491846394925654e-16 1.5109208910009617e-16 5295/2246/8817/2261/4893/2247/5290/5335/3845/8823/2549/2254/3265/2249/26281/6654/10818/2885/8074 19 Dengue_virus_type_4 R-HSA-1963640 GRB2 events in ERBB2 signaling 16/980 16/10654 2.3488030937889427e-17 2.764170377743198e-16 1.6760434264820821e-16 2064/1839/4893/1956/685/145957/3084/3845/3265/1950/2066/2069/6654/9542/2885/10718 16 Dengue_virus_type_4 R-HSA-1963642 PI3K events in ERBB2 signaling 16/980 16/10654 2.3488030937889427e-17 2.764170377743198e-16 1.6760434264820821e-16 5295/2064/1839/1956/685/5290/145957/3084/2549/2065/1950/2066/2069/9542/2885/10718 16 Dengue_virus_type_4 R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 16/980 16/10654 2.3488030937889427e-17 2.764170377743198e-16 1.6760434264820821e-16 5295/5170/9846/4067/2206/6464/5290/5296/2205/2534/5291/6850/2207/6654/2885/7462 16 Dengue_virus_type_4 R-HSA-5654719 SHC-mediated cascade:FGFR4 18/980 20/10654 3.060701823210907e-17 3.4916986105610143e-16 2.1171772010180712e-16 2246/8817/2251/4893/6464/2247/3845/8823/9965/2254/152831/3265/2264/2249/26281/6654/2885/8074 18 Dengue_virus_type_4 R-HSA-5654720 PI-3K cascade:FGFR4 18/980 20/10654 3.060701823210907e-17 3.4916986105610143e-16 2.1171772010180712e-16 5295/2246/8817/2251/2247/5290/8823/9965/2549/2254/152831/2264/5781/2249/26281/10818/2885/8074 18 Dengue_virus_type_4 R-HSA-8964616 G beta:gamma signalling through CDC42 18/980 20/10654 3.060701823210907e-17 3.4916986105610143e-16 2.1171772010180712e-16 2788/10681/51764/94235/2793/54331/2785/2783/2784/59345/55970/2782/998/2791/2786/2792/2790/2787 18 Dengue_virus_type_4 R-HSA-187037 Signaling by NTRK1 (TRKA) 36/980 80/10654 3.688243151226982e-17 4.1651069121937027e-16 2.5254955761724363e-16 5295/8660/1385/1432/5906/1759/5518/1213/4893/387/6464/5290/4914/5296/3667/5335/3845/5600/4915/5291/5604/673/4803/3265/1399/6774/6714/5594/5605/6654/10818/2885/5595/1398/5515/5607 36 Dengue_virus_type_4 R-HSA-9006335 Signaling by Erythropoietin 20/980 25/10654 5.338619968293794e-17 5.968577124552462e-16 3.6190223785065303e-16 5295/7409/8660/5293/4067/23533/3717/4893/6464/5290/5335/5294/3845/2549/5291/3265/1399/5336/6654/2885 20 Dengue_virus_type_4 R-HSA-5655253 Signaling by FGFR2 in disease 26/980 43/10654 7.616645135155736e-17 8.431098278320904e-16 5.1121620292238615e-16 5295/2962/2248/2246/8817/2251/4893/2252/2247/5290/2255/5335/3845/8823/2549/2254/3265/2263/5430/27006/2249/26281/6654/10818/2885/8074 26 Dengue_virus_type_4 R-HSA-5654733 Negative regulation of FGFR4 signaling 22/980 31/10654 1.1490307713329457e-16 1.2594278454414052e-15 7.63648933682577e-16 2246/8817/2251/867/5518/2247/8823/9965/2254/673/152831/2264/5781/2249/26281/6714/5594/10818/2885/5595/5515/8074 22 Dengue_virus_type_4 R-HSA-9006931 Signaling by Nuclear Receptors 75/980 299/10654 2.1950274577456743e-16 2.382563784232683e-15 1.4446578260482517e-15 5295/2788/2962/10681/1385/1025/2353/8850/8503/51764/5170/3725/94235/1387/4318/5163/2793/5590/1839/1386/4893/6464/1956/685/5914/5290/54331/5296/10000/3320/3845/2033/5241/2100/2309/4313/2785/3265/2783/1950/5747/2784/59345/55970/1105/801/2782/1655/3065/4314/5430/2770/8877/2066/3480/207/2791/1903/2786/6667/2792/346562/2771/2773/6714/2099/5594/208/2069/2957/4609/5595/2790/2787/6387 75 Dengue_virus_type_4 R-HSA-5637810 Constitutive Signaling by EGFRvIII 15/980 15/10654 2.5895249859917767e-16 2.757227556513149e-15 1.6718336751666208e-15 5295/867/4893/6464/1956/5290/3320/5335/3845/2549/3265/1950/11140/6654/2885 15 Dengue_virus_type_4 R-HSA-5637812 Signaling by EGFRvIII in Cancer 15/980 15/10654 2.5895249859917767e-16 2.757227556513149e-15 1.6718336751666208e-15 5295/867/4893/6464/1956/5290/3320/5335/3845/2549/3265/1950/11140/6654/2885 15 Dengue_virus_type_4 R-HSA-933541 TRAF6 mediated IRF7 activation 21/980 29/10654 2.970634126484379e-16 3.1331782579335245e-15 1.899789848516326e-15 3443/3665/1387/3451/3441/3449/3448/3444/3452/7186/2033/64135/3456/3661/29110/7189/3446/3440/57506/3445/23586 21 Dengue_virus_type_4 R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 17/980 19/10654 3.043911952883463e-16 3.151012558633066e-15 1.9106036039541425e-15 51343/25906/11065/8881/29882/119504/246184/7321/51529/7324/64682/29945/10393/8697/996/51434/51433 17 Dengue_virus_type_4 R-HSA-392851 Prostacyclin signalling through prostacyclin receptor 17/980 19/10654 3.043911952883463e-16 3.151012558633066e-15 1.9106036039541425e-15 2788/10681/51764/94235/2793/54331/2785/2783/2784/59345/55970/2782/2791/2786/2792/2790/2787 17 Dengue_virus_type_4 R-HSA-445717 Aquaporin-mediated transport 28/980 52/10654 3.2914550438998777e-16 3.3760061826422597e-15 2.0470275695524107e-15 2788/10681/51764/112/94235/114/2793/108/54331/113/196883/2785/115/2783/8766/2784/59345/55970/2782/111/107/551/2791/2786/109/2792/2790/2787 28 Dengue_virus_type_4 R-HSA-451326 Activation of kainate receptors upon glutamate binding 22/980 32/10654 3.360264374435784e-16 3.4152505187447333e-15 2.0708232125709523e-15 2788/10681/51764/94235/2793/5330/23236/54331/2785/5331/2783/2784/59345/55970/801/2782/2791/2786/2792/1739/2790/2787 22 Dengue_virus_type_4 R-HSA-76009 Platelet Aggregation (Plug Formation) 24/980 39/10654 6.753611462453382e-16 6.802286139660253e-15 4.124538437003299e-15 151/5908/4352/5170/5906/6464/9564/150/2335/3690/5770/5747/1445/6850/207/3674/7094/2147/6714/6654/152/2885/1398/7066 24 Dengue_virus_type_4 R-HSA-389356 CD28 co-stimulation 22/980 33/10654 9.212779474248713e-16 9.196328082330412e-15 5.57615599757159e-15 2475/5295/7409/8503/5170/941/3932/9402/4067/5290/5296/10000/2534/998/207/942/6714/208/940/5879/2885/7525 22 Dengue_virus_type_4 R-HSA-168898 Toll-like Receptor Cascades 49/980 155/10654 2.656774556776685e-15 2.6285610216604726e-14 1.5938172469158688e-14 54106/51135/1385/2353/3665/1432/3725/1759/5518/1386/351/10333/7099/4615/81793/929/7098/7100/4790/5599/5600/3656/5604/7097/11213/3551/7321/5781/6288/30849/5970/4792/7096/5289/5336/3661/695/59307/3654/6279/29110/7189/5594/8651/51284/5595/51311/5515/3146 49 Dengue_virus_type_4 R-HSA-1250347 SHC1 events in ERBB4 signaling 14/980 14/10654 2.8522304193532505e-15 2.7971873761727492e-14 1.696063148719754e-14 1839/4893/6464/685/145957/3084/3845/3265/2066/2069/6654/9542/2885/10718 14 Dengue_virus_type_4 R-HSA-977443 GABA receptor activation 28/980 56/10654 4.112773415314576e-15 3.993665015767832e-14 2.4215424820209815e-14 2788/112/94235/114/2793/108/54331/113/196883/2785/115/2783/2784/55970/2782/2770/111/107/9568/2786/109/2792/2550/346562/2771/2773/2790/2787 28 Dengue_virus_type_4 R-HSA-5654693 FRS-mediated FGFR1 signaling 18/980 23/10654 4.1436953651973934e-15 3.993665015767832e-14 2.4215424820209815e-14 2248/2246/2251/4893/2247/2260/2255/3845/2254/3265/5781/27006/2249/26281/6654/10818/2885/8074 18 Dengue_virus_type_4 R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 35/980 86/10654 4.590997344790265e-15 4.386953018355142e-14 2.660011057170428e-14 5295/7409/2209/10451/4067/60/5290/5296/5581/917/3320/5335/919/2534/5291/2214/5747/2212/4690/10006/998/5336/3055/6850/695/6714/5594/5879/2885/7525/5595/1398/7410/5580/2268 35 Dengue_virus_type_4 R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 21/980 32/10654 6.818342953628459e-15 6.460091035725948e-14 3.917049832414566e-14 5295/7409/930/5777/5293/4067/29760/118788/27071/2534/4690/801/973/933/5336/6850/695/974/6654/30011/2885 21 Dengue_virus_type_4 R-HSA-5654688 SHC-mediated cascade:FGFR1 17/980 21/10654 8.910570492708495e-15 8.301681509040082e-14 5.033690699389712e-14 2248/2246/2251/4893/6464/2247/2260/2255/3845/2254/3265/27006/2249/26281/6654/2885/8074 17 Dengue_virus_type_4 R-HSA-5654689 PI-3K cascade:FGFR1 17/980 21/10654 8.910570492708495e-15 8.301681509040082e-14 5.033690699389712e-14 5295/2248/2246/2251/2247/5290/2260/2255/2549/2254/5781/27006/2249/26281/10818/2885/8074 17 Dengue_virus_type_4 R-HSA-8848021 Signaling by PTK6 27/980 54/10654 1.2792631084671126e-14 1.1723083239887147e-13 7.108243674312516e-14 867/2064/1839/4893/387/1956/685/2908/145957/9564/3084/3845/5770/2065/3265/1950/6774/2066/207/9021/5829/2069/9542/5879/27043/1398/10718 27 Dengue_virus_type_4 R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 27/980 54/10654 1.2792631084671126e-14 1.1723083239887147e-13 7.108243674312516e-14 867/2064/1839/4893/387/1956/685/2908/145957/9564/3084/3845/5770/2065/3265/1950/6774/2066/207/9021/5829/2069/9542/5879/27043/1398/10718 27 Dengue_virus_type_4 R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 22/980 36/10654 1.3794342940096419e-14 1.2538272688640485e-13 7.602530469338549e-14 409/5908/7414/5906/4893/60/2335/3845/3690/408/5604/673/3265/369/1445/5894/3674/7094/6714/5594/5605/5595 22 Dengue_virus_type_4 R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 44/980 134/10654 1.538617669660297e-14 1.3872375440969453e-13 8.411458228024035e-14 5295/7409/3702/2353/5170/3725/9846/27040/10451/9402/4067/4893/2206/6464/5588/5290/5296/2205/5335/4790/3845/5599/2534/5291/3265/3551/801/7321/3937/5970/4792/5336/6850/695/2207/7189/5594/6654/5879/2885/7294/5595/7462/7410 44 Dengue_virus_type_4 R-HSA-5654726 Negative regulation of FGFR1 signaling 21/980 33/10654 1.713820671448482e-14 1.5328412085435223e-13 9.29432010452903e-14 2248/2246/2251/867/5518/2247/2260/2255/2254/673/5781/27006/2249/26281/6714/5594/10818/2885/5595/5515/8074 21 Dengue_virus_type_4 R-HSA-176412 Phosphorylation of the APC/C 16/980 19/10654 1.7420162388539522e-14 1.5456937738402529e-13 9.372251109623604e-14 25906/11065/8881/29882/119504/246184/7321/51529/7324/64682/29945/10393/8697/996/51434/51433 16 Dengue_virus_type_4 R-HSA-912631 Regulation of signaling by CBL 17/980 22/10654 3.585696687873645e-14 3.156542438616327e-13 1.913956624111585e-13 5295/7409/8503/867/5293/4067/29760/5290/5296/2534/5291/1399/3055/6850/2885/7525/1398 17 Dengue_virus_type_4 R-HSA-1643713 Signaling by EGFR in Cancer 18/980 25/10654 4.9494686610640813e-14 4.3230515336481587e-13 2.621264652734596e-13 5295/867/1839/4893/6464/1956/685/5290/3320/5335/3845/2549/3265/1950/11140/2069/6654/2885 18 Dengue_virus_type_4 R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 16/980 20/10654 7.967747248160335e-14 6.799955285071186e-13 4.123125132836687e-13 25906/11065/8881/29882/119504/246184/7321/51529/7324/64682/29945/10393/8697/996/51434/51433 16 Dengue_virus_type_4 R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 16/980 20/10654 7.967747248160335e-14 6.799955285071186e-13 4.123125132836687e-13 25906/11065/8881/29882/119504/246184/7321/51529/7324/64682/29945/10393/8697/996/51434/51433 16 Dengue_virus_type_4 R-HSA-5654706 FRS-mediated FGFR3 signaling 16/980 20/10654 7.967747248160335e-14 6.799955285071186e-13 4.123125132836687e-13 2246/8817/2261/4893/2247/3845/8823/2254/3265/5781/2249/26281/6654/10818/2885/8074 16 Dengue_virus_type_4 R-HSA-5654732 Negative regulation of FGFR3 signaling 19/980 29/10654 1.423739784458654e-13 1.2058644538066478e-12 7.31170989785784e-13 2246/8817/2261/867/5518/2247/8823/2254/673/5781/2249/26281/6714/5594/10818/2885/5595/5515/8074 19 Dengue_virus_type_4 R-HSA-5654221 Phospholipase C-mediated cascade; FGFR2 15/980 18/10654 1.6186662932930327e-13 1.3404954932604523e-12 8.128039710570863e-13 2248/2246/8817/2251/2252/2247/2255/5335/8823/2254/2263/27006/2249/26281/8074 15 Dengue_virus_type_4 R-HSA-5654704 SHC-mediated cascade:FGFR3 15/980 18/10654 1.6186662932930327e-13 1.3404954932604523e-12 8.128039710570863e-13 2246/8817/2261/4893/6464/2247/3845/8823/2254/3265/2249/26281/6654/2885/8074 15 Dengue_virus_type_4 R-HSA-5654710 PI-3K cascade:FGFR3 15/980 18/10654 1.6186662932930327e-13 1.3404954932604523e-12 8.128039710570863e-13 5295/2246/8817/2261/2247/5290/8823/2549/2254/5781/2249/26281/10818/2885/8074 15 Dengue_virus_type_4 R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 24/980 47/10654 2.1054597966448495e-13 1.69345615298485e-12 1.0268202264591316e-12 409/5908/7414/5906/3717/4893/60/2335/3845/3690/408/5604/673/3265/369/1445/801/5894/3674/7094/6714/5594/5605/5595 24 Dengue_virus_type_4 R-HSA-6802949 Signaling by RAS mutants 24/980 47/10654 2.1054597966448495e-13 1.69345615298485e-12 1.0268202264591316e-12 409/5908/7414/5906/3717/4893/60/2335/3845/3690/408/5604/673/3265/369/1445/801/5894/3674/7094/6714/5594/5605/5595 24 Dengue_virus_type_4 R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 24/980 47/10654 2.1054597966448495e-13 1.69345615298485e-12 1.0268202264591316e-12 409/5908/7414/5906/3717/4893/60/2335/3845/3690/408/5604/673/3265/369/1445/801/5894/3674/7094/6714/5594/5605/5595 24 Dengue_virus_type_4 R-HSA-9649948 Signaling downstream of RAS mutants 24/980 47/10654 2.1054597966448495e-13 1.69345615298485e-12 1.0268202264591316e-12 409/5908/7414/5906/3717/4893/60/2335/3845/3690/408/5604/673/3265/369/1445/801/5894/3674/7094/6714/5594/5605/5595 24 Dengue_virus_type_4 R-HSA-2871809 FCERI mediated Ca+2 mobilization 20/980 33/10654 2.807958413854762e-13 2.24235536192116e-12 1.359643021445464e-12 7409/3702/27040/10451/9402/4067/2206/6464/2205/5335/801/3937/5336/6850/695/2207/6654/2885/7294/7410 20 Dengue_virus_type_4 R-HSA-418038 Nucleotide-like (purinergic) receptors 14/980 16/10654 2.867285338846513e-13 2.2631420780222546e-12 1.3722469619116203e-12 5028/134/5031/5030/5032/10161/2846/5029/53829/140/9934/64805/2840/27334 14 Dengue_virus_type_4 R-HSA-5674135 MAP2K and MAPK activation 22/980 40/10654 2.874473837917354e-13 2.2631420780222546e-12 1.3722469619116203e-12 409/5908/7414/5906/4893/60/2335/3845/3690/408/5604/673/3265/369/1445/5894/3674/7094/6714/5594/5605/5595 22 Dengue_virus_type_4 R-HSA-2029481 FCGR activation 12/980 12/10654 3.4505511826457004e-13 2.6604939463433746e-12 1.6131796454619464e-12 2209/4067/917/919/2534/2214/2212/3055/6850/6714/7525/2268 12 Dengue_virus_type_4 R-HSA-210990 PECAM1 interactions 12/980 12/10654 3.4505511826457004e-13 2.6604939463433746e-12 1.6131796454619464e-12 3685/5777/3932/4067/3635/5335/2534/3690/5781/5175/6714/7525 12 Dengue_virus_type_4 R-HSA-417957 P2Y receptors 12/980 12/10654 3.4505511826457004e-13 2.6604939463433746e-12 1.6131796454619464e-12 5028/5031/5030/5032/10161/2846/5029/53829/9934/64805/2840/27334 12 Dengue_virus_type_4 R-HSA-170670 Adenylate cyclase inhibitory pathway 13/980 14/10654 4.023296648304469e-13 3.0481919661658864e-12 1.8482587573776773e-12 112/114/108/113/196883/115/2770/111/107/109/346562/2771/2773 13 Dengue_virus_type_4 R-HSA-354192 Integrin alphaIIb beta3 signaling 18/980 27/10654 4.0351736224736243e-13 3.0481919661658864e-12 1.8482587573776773e-12 5908/5170/5906/6464/9564/2335/3690/5770/5747/1445/6850/207/3674/7094/6714/6654/2885/1398 18 Dengue_virus_type_4 R-HSA-9006921 Integrin signaling 18/980 27/10654 4.0351736224736243e-13 3.0481919661658864e-12 1.8482587573776773e-12 5908/5170/5906/6464/9564/2335/3690/5770/5747/1445/6850/207/3674/7094/6714/6654/2885/1398 18 Dengue_virus_type_4 R-HSA-187687 Signalling to ERKs 20/980 34/10654 6.234050130476094e-13 4.677629560988103e-12 2.8362615923889827e-12 1432/5906/4893/6464/4914/3845/5600/5604/673/4803/3265/1399/6714/5594/5605/6654/10818/2885/5595/1398 20 Dengue_virus_type_4 R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 15/980 19/10654 7.03540880357173e-13 5.208998041319996e-12 3.158454701638337e-12 5295/867/4893/6464/1956/5290/3320/5335/3845/2549/3265/1950/11140/6654/2885 15 Dengue_virus_type_4 R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 15/980 19/10654 7.03540880357173e-13 5.208998041319996e-12 3.158454701638337e-12 5295/867/4893/6464/1956/5290/3320/5335/3845/2549/3265/1950/11140/6654/2885 15 Dengue_virus_type_4 R-HSA-416482 G alpha (12/13) signalling events 31/980 80/10654 8.235598467385447e-13 6.057499399037454e-12 3.672940036700989e-12 2788/7409/10681/146/6915/51764/94235/10451/9138/2793/387/54331/147/2785/2783/2784/59345/148/55970/2782/57580/695/2791/2786/2792/6654/2790/2787/7074/7410/10672 31 Dengue_virus_type_4 R-HSA-1855204 Synthesis of IP3 and IP4 in the cytosol 18/980 28/10654 1.033192778678014e-12 7.549735467725618e-12 4.5777512863339596e-12 113026/89869/5330/3635/3636/23236/5335/51196/5331/5728/801/84812/5336/5333/9651/23007/3633/5332 18 Dengue_virus_type_4 R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 22/980 42/10654 1.0881173117847667e-12 7.899449055684216e-12 4.789798693023854e-12 2788/10681/51764/112/94235/5906/114/2793/54331/2785/2783/2641/2784/59345/55970/2782/111/2791/2786/2792/2790/2787 22 Dengue_virus_type_4 R-HSA-2033519 Activated point mutants of FGFR2 14/980 17/10654 1.487205330486975e-12 1.0727068125706052e-11 6.50431397510093e-12 2248/2246/8817/2251/2252/2247/2255/8823/2254/2263/27006/2249/26281/8074 14 Dengue_virus_type_4 R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 40/980 129/10654 1.996504470217752e-12 1.4308282036560555e-11 8.675768413091986e-12 51135/1385/2353/3665/1432/3725/1759/5518/1386/351/10333/7099/4615/929/4790/5599/5600/3656/5604/7097/11213/3551/7321/5781/6288/5970/4792/7096/5336/3661/695/59307/3654/29110/7189/5594/8651/5595/5515/3146 40 Dengue_virus_type_4 R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission 53/980 206/10654 2.178748629394495e-12 1.5514910622057612e-11 9.407402731009418e-12 2788/88/2036/10681/1385/51764/112/5170/5563/94235/114/2793/5330/4893/108/23236/54331/3084/113/3845/196883/5579/2785/5331/115/3265/2783/2784/59345/55970/801/2782/2770/111/107/2066/2791/9568/2786/109/2792/2550/346562/5578/2771/2773/6714/5594/5879/1739/5595/2790/2787 53 Dengue_virus_type_4 R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 30/980 78/10654 2.425886774576625e-12 1.7165451987194093e-11 1.0408201751014967e-11 3443/7128/3665/1387/3451/3441/3449/351/3448/3444/3452/7186/4790/2033/64135/3551/3456/7321/6288/5970/4792/3661/29110/7189/3446/3440/57506/3445/3146/23586 30 Dengue_virus_type_4 R-HSA-5654228 Phospholipase C-mediated cascade; FGFR4 13/980 15/10654 2.762944697713902e-12 1.930607607527589e-11 1.1706160429787849e-11 2246/8817/2251/2247/5335/8823/9965/2254/152831/2264/2249/26281/8074 13 Dengue_virus_type_4 R-HSA-6785631 ERBB2 Regulates Cell Motility 13/980 15/10654 2.762944697713902e-12 1.930607607527589e-11 1.1706160429787849e-11 2064/1839/387/1956/685/145957/3084/2065/1950/2066/2069/9542/10718 13 Dengue_virus_type_4 R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 16/980 23/10654 3.0866411022069967e-12 2.143394256066722e-11 1.2996383588239988e-11 25906/11065/8881/29882/119504/246184/7321/51529/7324/64682/29945/10393/8697/996/51434/51433 16 Dengue_virus_type_4 R-HSA-5655291 Signaling by FGFR4 in disease 11/980 11/10654 3.789908796377519e-12 2.6155049594753493e-11 1.5859007568987147e-11 5295/4893/5290/5335/3845/2549/3265/2264/6654/10818/2885 11 Dengue_virus_type_4 R-HSA-202733 Cell surface interactions at the vascular wall 41/980 137/10654 3.84561503158804e-12 2.637667242524803e-11 1.599338766769582e-11 5295/914/3685/5777/3932/6403/4312/4067/3635/6383/4893/6382/6464/5290/5296/5196/682/5335/50848/2335/3845/2534/3690/3688/5291/9672/3265/5781/5175/6401/2207/2147/7010/6714/6654/2885/7525/284/51206/3655/285 41 Dengue_virus_type_4 R-HSA-420092 Glucagon-type ligand receptors 19/980 33/10654 4.067322388964577e-12 2.772723433452681e-11 1.681229536901918e-11 2788/10681/51764/94235/2793/2642/54331/2785/2783/2641/2784/59345/55970/2782/2791/2786/2792/2790/2787 19 Dengue_virus_type_4 R-HSA-8847993 ERBB2 Activates PTK6 Signaling 12/980 13/10654 4.109080542911932e-12 2.7842133618033576e-11 1.6881964080607875e-11 2064/1839/1956/685/145957/3084/2065/1950/2066/2069/9542/10718 12 Dengue_virus_type_4 R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 33/980 95/10654 5.343088860740024e-12 3.57699002772895e-11 2.1688933036978097e-11 51135/1385/2353/1432/3725/5518/1386/351/10333/7099/4615/929/4790/5599/5600/3656/5604/7097/11213/3551/6288/5970/4792/7096/695/59307/3654/7189/5594/8651/5595/5515/3146 33 Dengue_virus_type_4 R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 33/980 95/10654 5.343088860740024e-12 3.57699002772895e-11 2.1688933036978097e-11 51135/1385/2353/1432/3725/5518/1386/351/10333/7099/4615/929/4790/5599/5600/3656/5604/7097/11213/3551/6288/5970/4792/7096/695/59307/3654/7189/5594/8651/5595/5515/3146 33 Dengue_virus_type_4 R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 14/980 18/10654 6.1258907845388395e-12 4.0286740571261306e-11 2.442770071357903e-11 5295/399687/9846/8805/11052/26127/5290/9208/6774/7750/6772/1523/2885/613 14 Dengue_virus_type_4 R-HSA-210993 Tie2 Signaling 14/980 18/10654 6.1258907845388395e-12 4.0286740571261306e-11 2.442770071357903e-11 5295/4893/6464/5290/5296/3845/5291/3265/5781/7010/6654/2885/284/285 14 Dengue_virus_type_4 R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 14/980 18/10654 6.1258907845388395e-12 4.0286740571261306e-11 2.442770071357903e-11 1385/1839/4893/1956/3845/3265/4314/887/5578/5594/6654/2885/5595/2520 14 Dengue_virus_type_4 R-HSA-913531 Interferon Signaling 51/980 199/10654 6.708542536130946e-12 4.386052956370993e-11 2.6594653082599748e-11 3459/3443/3665/1958/3123/3460/5777/3133/2209/3383/3451/3441/3449/3717/3448/10379/3444/3452/5335/3662/5770/3122/3455/3456/6773/7412/3458/3454/7297/3663/5781/3664/567/3105/3661/7324/9021/3660/5724/3434/3446/6772/3440/8651/3659/4599/3445/5595/5580/3716/23586 51 Dengue_virus_type_4 R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress 17/980 27/10654 7.352178473782678e-12 4.7789160079587406e-11 2.897676216105291e-11 5393/6347/1051/11340/3576/51010/468/56915/8570/23404/51013/5073/23016/54512/118460/167227/22894 17 Dengue_virus_type_4 R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 21/980 42/10654 1.1581671731783098e-11 7.484571674065609e-11 4.53823948601662e-11 2788/10681/51764/94235/2793/54331/2785/2783/2784/59345/55970/2782/2770/2791/2786/2792/346562/2771/2773/2790/2787 21 Dengue_virus_type_4 R-HSA-1433559 Regulation of KIT signaling 13/980 16/10654 1.3493214740974118e-11 8.669778207131646e-11 5.2568846298773946e-11 5777/867/3932/4067/4254/2534/3815/5578/6714/8651/6654/2885/7525 13 Dengue_virus_type_4 R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 33/980 98/10654 1.4182459473300193e-11 9.009085051789554e-11 5.462621950242419e-11 51135/1385/2353/1432/3725/5518/1386/351/10333/7099/4615/929/4790/5599/5600/3656/5604/7097/11213/3551/6288/5970/4792/7096/695/59307/3654/7189/5594/8651/5595/5515/3146 33 Dengue_virus_type_4 R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 33/980 98/10654 1.4182459473300193e-11 9.009085051789554e-11 5.462621950242419e-11 51135/1385/2353/1432/3725/5518/1386/351/10333/7099/4615/929/4790/5599/5600/3656/5604/7097/11213/3551/6288/5970/4792/7096/695/59307/3654/7189/5594/8651/5595/5515/3146 33 Dengue_virus_type_4 R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 16/980 25/10654 2.1528955309063124e-11 1.3598515274312188e-10 8.24540423374169e-11 25906/11065/8881/29882/119504/246184/7321/51529/7324/64682/29945/10393/8697/996/51434/51433 16 Dengue_virus_type_4 R-HSA-6806834 Signaling by MET 29/980 79/10654 2.191746634441282e-11 1.3766138973625582e-10 8.347042179658107e-11 5295/5908/3082/284217/5906/867/382/3918/4893/6464/5290/3912/2335/3845/2549/3688/5770/3265/1399/5747/5781/6774/4233/6714/6654/30011/5879/2885/1398 29 Dengue_virus_type_4 R-HSA-190322 FGFR4 ligand binding and activation 12/980 14/10654 2.634958581140094e-11 1.6457450802875003e-10 9.978908122635817e-11 2246/8817/2251/2247/8823/9965/2254/152831/2264/2249/26281/8074 12 Dengue_virus_type_4 R-HSA-8863795 Downregulation of ERBB2 signaling 17/980 29/10654 3.7839449078328945e-11 2.35025022608732e-10 1.42506463195578e-10 2064/1839/1956/685/10000/145957/3320/3084/2065/1950/2066/207/11140/208/2069/9542/10718 17 Dengue_virus_type_4 R-HSA-1250342 PI3K events in ERBB4 signaling 10/980 10/10654 4.1587411575920056e-11 2.5546552825208035e-10 1.5490048036375083e-10 5295/1839/685/5290/145957/3084/2066/2069/9542/10718 10 Dengue_virus_type_4 R-HSA-8853334 Signaling by FGFR3 fusions in cancer 10/980 10/10654 4.1587411575920056e-11 2.5546552825208035e-10 1.5490048036375083e-10 5295/2261/4893/5290/3845/2549/3265/6654/10818/2885 10 Dengue_virus_type_4 R-HSA-4086398 Ca2+ pathway 25/980 62/10654 4.890091098199945e-11 2.987498277479529e-10 1.811457386966215e-10 2788/10681/51764/94235/2793/5330/23236/54331/3845/2785/5331/1499/2783/2784/59345/55970/801/2782/2791/2786/2792/7976/5578/2790/2787 25 Dengue_virus_type_4 R-HSA-180292 GAB1 signalosome 13/980 17/10654 5.251274532505705e-11 3.1734729336980423e-10 1.9242223607019485e-10 5295/1839/1956/685/5290/2549/1950/1445/5781/6714/5829/2069/2885 13 Dengue_virus_type_4 R-HSA-9034015 Signaling by NTRK3 (TRKC) 13/980 17/10654 5.251274532505705e-11 3.1734729336980423e-10 1.9242223607019485e-10 5295/4908/4893/6464/5290/3667/5335/3845/3265/4916/6714/6654/2885 13 Dengue_virus_type_4 R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 32/980 97/10654 5.35612032508571e-11 3.219431464218185e-10 1.9520891281014135e-10 54106/51135/1385/2353/3665/1432/3725/5518/1386/351/7099/4615/929/4790/5599/5600/3656/5604/3551/6288/30849/5970/4792/5289/3654/7189/5594/51284/5595/51311/5515/3146 32 Dengue_virus_type_4 R-HSA-177929 Signaling by EGFR 22/980 49/10654 5.609659215000235e-11 3.353796257952012e-10 2.033560672367099e-10 5295/867/1839/4893/6464/1956/685/5290/5335/3845/2549/3265/1950/1445/5781/998/6714/5829/2069/6654/30011/2885 22 Dengue_virus_type_4 R-HSA-1236394 Signaling by ERBB4 24/980 58/10654 6.22024242511118e-11 3.699059059188457e-10 2.242909362694065e-10 5295/1839/4893/6464/1956/685/5290/145957/3084/3845/5241/2065/3265/1950/2066/11033/6714/2099/2069/6654/9542/2885/10718/6387 24 Dengue_virus_type_4 R-HSA-190241 FGFR2 ligand binding and activation 14/980 20/10654 6.501959581152891e-11 3.8461327046184825e-10 2.332086867314098e-10 2248/2246/8817/2251/2252/2247/2255/8823/2254/2263/27006/2249/26281/8074 14 Dengue_virus_type_4 R-HSA-3928665 EPH-ephrin mediated repulsion of cells 22/980 51/10654 1.4719033407877852e-10 8.660989131582863e-10 5.251555409791323e-10 2050/10451/4318/1759/1213/4067/60/2047/2534/2046/4313/1946/1947/1948/1969/6714/2048/5879/7525/7074/1942/7410 22 Dengue_virus_type_4 R-HSA-5260271 Diseases of Immune System 15/980 24/10654 1.5230630153809435e-10 8.868669016645286e-10 5.377481260445875e-10 51135/10333/7099/4615/81793/929/7098/7100/4790/7097/3551/5970/4792/7096/695 15 Dengue_virus_type_4 R-HSA-5602358 Diseases associated with the TLR signaling cascade 15/980 24/10654 1.5230630153809435e-10 8.868669016645286e-10 5.377481260445875e-10 51135/10333/7099/4615/81793/929/7098/7100/4790/7097/3551/5970/4792/7096/695 15 Dengue_virus_type_4 R-HSA-389513 CTLA4 inhibitory signaling 14/980 21/10654 1.7856352750092957e-10 1.0290413595156664e-9 6.239550282723746e-10 941/3932/5518/4067/10000/2534/5781/1493/207/942/6714/208/7525/5515 14 Dengue_virus_type_4 R-HSA-5218921 VEGFR2 mediated cell proliferation 14/980 21/10654 1.7856352750092957e-10 1.0290413595156664e-9 6.239550282723746e-10 5170/5590/3791/4893/5335/3845/5579/3265/801/8877/7422/5578/6714/5580 14 Dengue_virus_type_4 R-HSA-381042 PERK regulates gene expression 17/980 32/10654 3.15722884696271e-10 1.8101445389252871e-9 1.0975737530061999e-9 5393/6347/1051/11340/3576/51010/468/56915/8570/23404/51013/5073/23016/54512/118460/167227/22894 17 Dengue_virus_type_4 R-HSA-1296041 Activation of G protein gated Potassium channels 15/980 25/10654 3.4847232088163994e-10 1.967636640129664e-9 1.193068445761702e-9 2788/94235/2793/54331/2785/2783/2784/55970/2782/9568/2786/2792/2550/2790/2787 15 Dengue_virus_type_4 R-HSA-1296059 G protein gated Potassium channels 15/980 25/10654 3.4847232088163994e-10 1.967636640129664e-9 1.193068445761702e-9 2788/94235/2793/54331/2785/2783/2784/55970/2782/9568/2786/2792/2550/2790/2787 15 Dengue_virus_type_4 R-HSA-997272 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits 15/980 25/10654 3.4847232088163994e-10 1.967636640129664e-9 1.193068445761702e-9 2788/94235/2793/54331/2785/2783/2784/55970/2782/9568/2786/2792/2550/2790/2787 15 Dengue_virus_type_4 R-HSA-6802952 Signaling by BRAF and RAF fusions 25/980 67/10654 3.53826948984181e-10 1.9878318038407757e-9 1.2053137008506355e-9 409/5908/7414/5906/8805/3717/4893/60/2335/3845/3690/408/5604/673/3265/369/1445/801/5894/3674/7094/6714/5594/5605/5595 25 Dengue_virus_type_4 R-HSA-1660499 Synthesis of PIPs at the plasma membrane 22/980 53/10654 3.644651283132417e-10 2.037360067271021e-9 1.2353449612301455e-9 5295/79837/8503/146850/23396/5293/8395/23533/3635/3636/5305/5290/5296/5294/8394/375/5291/5728/5868/8871/5287/8396 22 Dengue_virus_type_4 R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 30/980 93/10654 3.999897010524558e-10 2.2138043850328986e-9 1.3423312531411233e-9 54106/51135/1385/2353/3665/1432/3725/5518/1386/351/7099/4615/929/4790/5599/5600/3656/5604/3551/6288/5970/4792/3654/7189/5594/51284/5595/51311/5515/3146 30 Dengue_virus_type_4 R-HSA-975155 MyD88 dependent cascade initiated on endosome 30/980 93/10654 3.999897010524558e-10 2.2138043850328986e-9 1.3423312531411233e-9 54106/51135/1385/2353/3665/1432/3725/5518/1386/351/7099/4615/929/4790/5599/5600/3656/5604/3551/6288/5970/4792/3654/7189/5594/51284/5595/51311/5515/3146 30 Dengue_virus_type_4 R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 10/980 11/10654 4.1956243937134285e-10 2.3106936316116322e-9 1.4010796523471343e-9 627/4893/4909/3845/4915/3265/5781/6654/10818/2885 10 Dengue_virus_type_4 R-HSA-5654219 Phospholipase C-mediated cascade: FGFR1 12/980 16/10654 4.4230495684167334e-10 2.4240046164166215e-9 1.4697853055007102e-9 2248/2246/2251/2247/2260/2255/5335/2254/27006/2249/26281/8074 12 Dengue_virus_type_4 R-HSA-389357 CD28 dependent PI3K/Akt signaling 14/980 22/10654 4.495384750753495e-10 2.4516293421182475e-9 1.4865354451785629e-9 2475/5295/8503/5170/941/3932/5290/5296/10000/2534/207/942/208/940 14 Dengue_virus_type_4 R-HSA-5218920 VEGFR2 mediated vascular permeability 16/980 29/10654 5.011446831179615e-10 2.719804639446024e-9 1.6491424421459746e-9 2475/7409/1003/5170/10451/10000/3320/1495/1499/3728/1500/801/207/208/5879/7410 16 Dengue_virus_type_4 R-HSA-112043 PLC beta mediated events 22/980 54/10654 5.622096879263521e-10 3.036475512568414e-9 1.8411545335599836e-9 1385/112/114/5330/108/23236/113/196883/5331/115/801/2770/111/107/109/346562/5578/2771/2773/5594/5332/5580 22 Dengue_virus_type_4 R-HSA-1500931 Cell-Cell communication 36/980 129/10654 6.979371088274171e-10 3.751411959947367e-9 2.2746533303889506e-9 5295/88/1003/5777/4868/3918/999/60/5290/5296/81/50848/2534/3688/7408/7305/5291/1495/1499/3728/5584/1500/3611/5747/4690/87/5781/1000/3691/89/6714/5829/7827/23607/2885/3655 36 Dengue_virus_type_4 R-HSA-112040 G-protein mediated events 22/980 55/10654 8.565472075508143e-10 4.58191281359718e-9 2.7782241332799018e-9 1385/112/114/5330/108/23236/113/196883/5331/115/801/2770/111/107/109/346562/5578/2771/2773/5594/5332/5580 22 Dengue_virus_type_4 R-HSA-169893 Prolonged ERK activation events 11/980 14/10654 1.0623118621772685e-9 5.575890431522001e-9 3.380918404952611e-9 5906/4914/5604/673/4803/1399/5594/5605/10818/5595/1398 11 Dengue_virus_type_4 R-HSA-180336 SHC1 events in EGFR signaling 11/980 14/10654 1.0623118621772685e-9 5.575890431522001e-9 3.380918404952611e-9 1839/4893/6464/1956/685/3845/3265/1950/2069/6654/2885 11 Dengue_virus_type_4 R-HSA-877312 Regulation of IFNG signaling 11/980 14/10654 1.0623118621772685e-9 5.575890431522001e-9 3.380918404952611e-9 3459/3460/5777/3717/5770/3458/5781/9021/6772/8651/3716 11 Dengue_virus_type_4 R-HSA-9027284 Erythropoietin activates RAS 11/980 14/10654 1.0623118621772685e-9 5.575890431522001e-9 3.380918404952611e-9 7409/8660/4067/3717/4893/6464/3845/3265/1399/6654/2885 11 Dengue_virus_type_4 R-HSA-450385 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA 12/980 17/10654 1.377806264481551e-9 7.198071979861561e-9 4.364521565794978e-9 5393/11340/51010/56915/23404/51013/23016/207/54512/118460/167227/22894 12 Dengue_virus_type_4 R-HSA-877300 Interferon gamma signaling 29/980 92/10654 1.445077444706516e-9 7.479613811027245e-9 4.535233305999008e-9 3459/3665/3123/3460/5777/3133/2209/3383/3717/10379/3662/5770/3122/7412/3458/3663/5781/3664/567/3105/3661/9021/3660/5724/6772/8651/3659/5580/3716 29 Dengue_virus_type_4 R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 29/980 92/10654 1.445077444706516e-9 7.479613811027245e-9 4.535233305999008e-9 54106/51135/1385/2353/1432/3725/5518/1386/351/7099/4615/929/4790/5599/5600/3656/5604/3551/6288/5970/4792/3654/7189/5594/51284/5595/51311/5515/3146 29 Dengue_virus_type_4 R-HSA-6802957 Oncogenic MAPK signaling 25/980 71/10654 1.4695221072662481e-9 7.571086248496153e-9 4.590697245110182e-9 409/5908/7414/5906/8805/3717/4893/60/2335/3845/3690/408/5604/673/3265/369/1445/801/5894/3674/7094/6714/5594/5605/5595 25 Dengue_virus_type_4 R-HSA-170968 Frs2-mediated activation 10/980 12/10654 2.3089581399499567e-9 1.1690661909028248e-8 7.088585132675071e-9 5906/4914/5604/673/4803/1399/5594/5605/10818/5595 10 Dengue_virus_type_4 R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 10/980 12/10654 2.3089581399499567e-9 1.1690661909028248e-8 7.088585132675071e-9 5295/8660/5293/4067/23533/3717/5290/5294/2549/5291 10 Dengue_virus_type_4 R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 14/980 24/10654 2.3109447959707004e-9 1.1690661909028248e-8 7.088585132675071e-9 1385/2353/1839/1956/685/10000/2309/1950/5747/207/5594/208/2069/5595 14 Dengue_virus_type_4 R-HSA-982772 Growth hormone receptor signaling 14/980 24/10654 2.3109447959707004e-9 1.1690661909028248e-8 7.088585132675071e-9 8660/5777/4067/3717/3667/5770/2690/6774/9021/2688/6772/5594/8651/5595 14 Dengue_virus_type_4 R-HSA-186797 Signaling by PDGF 22/980 58/10654 2.8277445945611835e-9 1.4240623678916229e-8 8.63474404408441e-9 5295/5154/5159/5155/4893/5290/5296/9564/5335/3845/5291/3265/1399/4690/5781/6774/6772/6714/5156/6654/2885/1398 22 Dengue_virus_type_4 R-HSA-391903 Eicosanoid ligand-binding receptors 11/980 15/10654 3.6517550699328044e-9 1.8307902099483744e-8 1.1100921713649874e-8 6915/10800/5731/11251/5733/5737/56413/57105/165140/1241/2840 11 Dengue_virus_type_4 R-HSA-170660 Adenylate cyclase activating pathway 9/980 10/10654 4.1849099613745525e-9 2.0702342198304203e-8 1.255278069457481e-8 112/114/108/113/196883/115/111/107/109 9 Dengue_virus_type_4 R-HSA-399997 Acetylcholine regulates insulin secretion 9/980 10/10654 4.1849099613745525e-9 2.0702342198304203e-8 1.255278069457481e-8 5330/23236/2769/5331/9630/2776/1131/2767/5578 9 Dengue_virus_type_4 R-HSA-74749 Signal attenuation 9/980 10/10654 4.1849099613745525e-9 2.0702342198304203e-8 1.255278069457481e-8 8660/3643/6464/3667/3630/5594/6654/2885/5595 9 Dengue_virus_type_4 R-HSA-2029485 Role of phospholipids in phagocytosis 14/980 25/10654 4.808637036993144e-9 2.3683066992767996e-8 1.4360131007760656e-8 5295/2209/5290/5296/5581/917/5335/919/5291/2214/2212/5336/6850/5580 14 Dengue_virus_type_4 R-HSA-1839126 FGFR2 mutant receptor activation 16/980 33/10654 6.040384884253779e-9 2.9489739303911465e-8 1.7880983063477057e-8 2962/2248/2246/8817/2251/2252/2247/2255/8823/2254/2263/5430/27006/2249/26281/8074 16 Dengue_virus_type_4 R-HSA-202433 Generation of second messenger molecules 16/980 33/10654 6.040384884253779e-9 2.9489739303911465e-8 1.7880983063477057e-8 3702/3123/27040/3932/9402/915/917/5335/919/7408/3122/4690/916/3937/920/7535 16 Dengue_virus_type_4 R-HSA-2682334 EPH-Ephrin signaling 28/980 92/10654 6.698955558311996e-9 3.256274919214266e-8 1.974429006660378e-8 2050/10451/4318/1759/1213/4067/6383/387/60/2047/2534/2046/4313/3265/1946/5747/1947/998/1948/4628/1969/6714/2048/5879/7525/7074/1942/7410 28 Dengue_virus_type_4 R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 31/980 110/10654 8.25518444145502e-9 3.995366322747494e-8 2.4225740625641522e-8 2353/51343/3552/3725/1051/25906/79813/3576/11065/8881/4790/29882/119504/246184/1029/7321/6774/3569/5970/51529/7324/64682/29945/10393/8697/10919/5594/996/5595/51434/51433 31 Dengue_virus_type_4 R-HSA-179812 GRB2 events in EGFR signaling 10/980 13/10654 9.177680265864748e-9 4.384891682579824e-8 2.6587611746364813e-8 1839/4893/1956/685/3845/3265/1950/2069/6654/2885 10 Dengue_virus_type_4 R-HSA-190375 FGFR2c ligand binding and activation 10/980 13/10654 9.177680265864748e-9 4.384891682579824e-8 2.6587611746364813e-8 2246/8817/2251/2247/8823/2254/2263/2249/26281/8074 10 Dengue_virus_type_4 R-HSA-5654227 Phospholipase C-mediated cascade; FGFR3 10/980 13/10654 9.177680265864748e-9 4.384891682579824e-8 2.6587611746364813e-8 2246/8817/2261/2247/5335/8823/2254/2249/26281/8074 10 Dengue_virus_type_4 R-HSA-166166 MyD88-independent TLR4 cascade 29/980 99/10654 9.541282136057203e-9 4.519980266149133e-8 2.7406715859147362e-8 1385/2353/3665/1432/3725/5518/1386/351/7099/929/4790/5599/5600/3656/5604/3551/7321/5781/6288/5970/4792/3661/3654/29110/7189/5594/5595/5515/3146 29 Dengue_virus_type_4 R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 29/980 99/10654 9.541282136057203e-9 4.519980266149133e-8 2.7406715859147362e-8 1385/2353/3665/1432/3725/5518/1386/351/7099/929/4790/5599/5600/3656/5604/3551/7321/5781/6288/5970/4792/3661/3654/29110/7189/5594/5595/5515/3146 29 Dengue_virus_type_4 R-HSA-190242 FGFR1 ligand binding and activation 11/980 16/10654 1.071254531873331e-8 5.032195658127664e-8 3.0512512982150604e-8 2248/2246/2251/2247/2260/2255/2254/27006/2249/26281/8074 11 Dengue_virus_type_4 R-HSA-193639 p75NTR signals via NF-kB 11/980 16/10654 1.071254531873331e-8 5.032195658127664e-8 3.0512512982150604e-8 4804/4615/4790/5584/4803/3551/5970/4792/3654/7189/8878 11 Dengue_virus_type_4 R-HSA-373753 Nephrin family interactions 13/980 23/10654 1.489518961425551e-8 6.967707945078518e-8 4.2248412735435147e-8 5295/88/4868/5290/5296/81/2534/5291/4690/87/89/7827/23607 13 Dengue_virus_type_4 R-HSA-202403 TCR signaling 32/980 119/10654 1.6627587819326244e-8 7.745684659169475e-8 4.696564278792149e-8 5295/3702/3123/5170/27040/3932/9402/3635/915/5588/5290/5296/917/5335/4790/919/7408/5291/5728/3122/3551/4690/1445/916/7321/3937/920/5970/4792/50852/7189/7535 32 Dengue_virus_type_4 R-HSA-1296065 Inwardly rectifying K+ channels 15/980 31/10654 1.8837353810191814e-8 8.738656248877365e-8 5.298648549361664e-8 2788/94235/2793/54331/2785/2783/2784/55970/2782/9568/2786/2792/2550/2790/2787 15 Dengue_virus_type_4 R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 26/980 85/10654 2.062140245238431e-8 9.44865899252691e-8 5.729155815071397e-8 51135/1385/2353/1432/3725/5518/1386/351/4615/81793/7100/4790/5599/5600/3656/5604/3551/6288/5970/4792/3654/7189/5594/5595/5515/3146 26 Dengue_virus_type_4 R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 26/980 85/10654 2.062140245238431e-8 9.44865899252691e-8 5.729155815071397e-8 51135/1385/2353/1432/3725/5518/1386/351/4615/81793/7100/4790/5599/5600/3656/5604/3551/6288/5970/4792/3654/7189/5594/5595/5515/3146 26 Dengue_virus_type_4 R-HSA-975871 MyD88 cascade initiated on plasma membrane 26/980 85/10654 2.062140245238431e-8 9.44865899252691e-8 5.729155815071397e-8 51135/1385/2353/1432/3725/5518/1386/351/4615/81793/7100/4790/5599/5600/3656/5604/3551/6288/5970/4792/3654/7189/5594/5595/5515/3146 26 Dengue_virus_type_4 R-HSA-1059683 Interleukin-6 signaling 9/980 11/10654 2.1128973810389086e-8 9.602517365859756e-8 5.822447211763188e-8 867/3717/7297/5781/6774/3569/9021/6772/3716 9 Dengue_virus_type_4 R-HSA-8875555 MET activates RAP1 and RAC1 9/980 11/10654 2.1128973810389086e-8 9.602517365859756e-8 5.822447211763188e-8 5908/3082/5906/2549/1399/4233/5879/2885/1398 9 Dengue_virus_type_4 R-HSA-450513 Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA 11/980 17/10654 2.782623358486162e-8 1.2595032043674208e-7 7.636946272597863e-8 5393/11340/51010/56915/23404/51013/23016/54512/118460/167227/22894 11 Dengue_virus_type_4 R-HSA-8983432 Interleukin-15 signaling 10/980 14/10654 2.9466101275083624e-8 1.3283508558686892e-7 8.054401197433724e-8 9846/6464/3600/3561/3560/6774/3718/6654/2885/3716 10 Dengue_virus_type_4 R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 13/980 24/10654 2.9767478944955877e-8 1.3365478498176976e-7 8.104103335680231e-8 1432/5590/5880/5579/5600/30849/5289/6279/5578/5594/5879/5595/5580 13 Dengue_virus_type_4 R-HSA-418346 Platelet homeostasis 26/980 88/10654 4.567524395035516e-8 2.042596909459883e-7 1.238520299116999e-7 2788/10681/51764/1432/94235/5777/2793/5518/54331/4843/2785/2783/2784/59345/55970/801/2782/5781/5175/2791/2786/2792/2790/5515/2787/2268 26 Dengue_virus_type_4 R-HSA-445144 Signal transduction by L1 12/980 21/10654 4.613463869838019e-8 2.0549213571629104e-7 1.2459931776790456e-7 3685/1956/2260/3690/3688/5604/3674/5594/5605/5879/5595/7410 12 Dengue_virus_type_4 R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 21/980 61/10654 4.7699099737985506e-8 2.1161743455185633e-7 1.2831336771621832e-7 7409/2209/10451/60/917/3320/919/2214/5747/2212/4690/10006/998/6850/695/5594/5879/2885/5595/1398/7410 21 Dengue_virus_type_4 R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 27/980 94/10654 4.8741060784116034e-8 2.153853990381096e-7 1.3059805760337313e-7 1385/2353/3665/1432/3725/5518/1386/351/7098/4790/5599/5600/3656/5604/3551/7321/6288/5970/4792/3661/3654/29110/7189/5594/5595/5515/3146 27 Dengue_virus_type_4 R-HSA-983705 Signaling by the B Cell Receptor (BCR) 30/980 112/10654 5.1227183965960325e-8 2.254802821808805e-7 1.3671904879435746e-7 5295/7409/930/5777/5293/4067/29760/4893/118788/4790/3845/27071/2534/5579/3265/3551/4690/801/973/933/5970/4792/5336/6850/695/25780/974/6654/30011/2885 30 Dengue_virus_type_4 R-HSA-8854691 Interleukin-20 family signaling 13/980 25/10654 5.680622434524844e-8 2.4905630909014806e-7 1.5101427648437563e-7 282618/53832/3717/11009/3588/6773/7297/5781/6774/3718/163702/6772/3716 13 Dengue_virus_type_4 R-HSA-3928662 EPHB-mediated forward signaling 17/980 42/10654 5.838390791806248e-8 2.549734728609135e-7 1.5460212458565888e-7 2050/4067/6383/387/60/2047/2534/3265/5747/1947/998/1948/6714/2048/5879/7525/7074 17 Dengue_virus_type_4 R-HSA-1483255 PI Metabolism 25/980 84/10654 7.055254928142436e-8 3.069173155510989e-7 1.8609806159015886e-7 5295/79837/8503/146850/23396/5293/8395/23533/3635/3636/5305/5290/5296/200576/5294/8394/375/5291/5728/5868/30849/5289/8871/5287/8396 25 Dengue_virus_type_4 R-HSA-1839130 Signaling by activated point mutants of FGFR3 9/980 12/10654 7.758902082170642e-8 3.310859743460602e-7 2.0075262920521872e-7 2246/8817/2261/2247/8823/2254/2249/26281/8074 9 Dengue_virus_type_4 R-HSA-2033514 FGFR3 mutant receptor activation 9/980 12/10654 7.758902082170642e-8 3.310859743460602e-7 2.0075262920521872e-7 2246/8817/2261/2247/8823/2254/2249/26281/8074 9 Dengue_virus_type_4 R-HSA-389359 CD28 dependent Vav1 pathway 9/980 12/10654 7.758902082170642e-8 3.310859743460602e-7 2.0075262920521872e-7 7409/941/3932/2534/998/942/940/5879/2885 9 Dengue_virus_type_4 R-HSA-390666 Serotonin receptors 9/980 12/10654 7.758902082170642e-8 3.310859743460602e-7 2.0075262920521872e-7 3356/3357/3352/3355/3351/3350/3354/3361/3358 9 Dengue_virus_type_4 R-HSA-9020558 Interleukin-2 signaling 9/980 12/10654 7.758902082170642e-8 3.310859743460602e-7 2.0075262920521872e-7 3932/3558/6464/3561/3559/3560/6850/3718/3716 9 Dengue_virus_type_4 R-HSA-354194 GRB2:SOS provides linkage to MAPK signaling for Integrins 10/980 15/10654 8.1094793685385e-8 3.434241641676531e-7 2.082338402447685e-7 5908/5906/2335/3690/5747/3674/7094/6714/6654/2885 10 Dengue_virus_type_4 R-HSA-372708 p130Cas linkage to MAPK signaling for integrins 10/980 15/10654 8.1094793685385e-8 3.434241641676531e-7 2.082338402447685e-7 5908/5906/9564/2335/3690/5747/3674/7094/6714/1398 10 Dengue_virus_type_4 R-HSA-112315 Transmission across Chemical Synapses 53/980 272/10654 9.392514575888693e-8 3.9625778474881353e-7 2.4026929044180014e-7 2788/88/2036/10681/1385/51764/112/5170/5563/94235/114/2793/5330/4893/108/23236/54331/3084/113/3845/196883/5579/2785/5331/115/3265/2783/2784/59345/55970/801/2782/2770/111/107/2066/2791/9568/2786/109/2792/2550/346562/5578/2771/2773/6714/5594/5879/1739/5595/2790/2787 53 Dengue_virus_type_4 R-HSA-450341 Activation of the AP-1 family of transcription factors 8/980 10/10654 1.8973286840675646e-7 7.974486724765178e-7 4.835297477402105e-7 2353/1432/3725/1386/5599/5600/5594/5595 8 Dengue_virus_type_4 R-HSA-429958 mRNA decay by 3' to 5' exoribonuclease 10/980 16/10654 1.983985409631381e-7 8.307474486771101e-7 5.037203247792665e-7 5393/11340/51010/56915/23404/51013/23016/54512/118460/22894 10 Dengue_virus_type_4 R-HSA-1483249 Inositol phosphate metabolism 18/980 50/10654 1.9972652646877024e-7 8.331875245973327e-7 5.051998548542343e-7 113026/89869/5330/3635/3636/23236/5335/51196/5331/5728/801/84812/5336/5333/9651/23007/3633/5332 18 Dengue_virus_type_4 R-HSA-190239 FGFR3 ligand binding and activation 9/980 13/10654 2.315145370723499e-7 9.551042525715394e-7 5.791235652538099e-7 2246/8817/2261/2247/8823/2254/2249/26281/8074 9 Dengue_virus_type_4 R-HSA-190372 FGFR3c ligand binding and activation 9/980 13/10654 2.315145370723499e-7 9.551042525715394e-7 5.791235652538099e-7 2246/8817/2261/2247/8823/2254/2249/26281/8074 9 Dengue_virus_type_4 R-HSA-209560 NF-kB is activated and signals survival 9/980 13/10654 2.315145370723499e-7 9.551042525715394e-7 5.791235652538099e-7 4804/4790/4803/3551/5970/4792/3654/7189/8878 9 Dengue_virus_type_4 R-HSA-390466 Chaperonin-mediated protein folding 26/980 95/10654 2.492358675119114e-7 1.0244327201408713e-6 6.211605985977979e-7 2788/10681/51764/94235/2793/60/54331/2785/55294/2783/2784/59345/55970/2782/6774/7157/2770/8877/2791/2786/2792/346562/2771/2773/2790/2787 26 Dengue_virus_type_4 R-HSA-8875878 MET promotes cell motility 16/980 41/10654 2.625973945795348e-7 1.0753988539923805e-6 6.52063705838521e-7 5908/3082/284217/5906/3918/3912/2335/2549/3688/1399/5747/4233/6714/5879/2885/1398 16 Dengue_virus_type_4 R-HSA-167044 Signalling to RAS 11/980 20/10654 2.9108088570922023e-7 1.1876950008135336e-6 7.201540161226963e-7 1432/4893/6464/4914/3845/5600/4803/3265/6714/6654/2885 11 Dengue_virus_type_4 R-HSA-446652 Interleukin-1 family signaling 33/980 140/10654 3.0576668968642584e-7 1.2430805784342694e-6 7.537368350547684e-7 51135/3557/834/3552/5777/351/4088/4615/4790/5599/3656/90865/5604/3565/11213/3551/5781/6288/6774/5970/4792/59307/3654/29110/3606/7189/3554/3553/8878/3596/54472/3146/3556 33 Dengue_virus_type_4 R-HSA-933542 TRAF6 mediated NF-kB activation 12/980 24/10654 3.2669089176015466e-7 1.3233348441588874e-6 8.023986815161694e-7 351/7186/4790/64135/3551/6288/5970/4792/7189/57506/3146/23586 12 Dengue_virus_type_4 R-HSA-111931 PKA-mediated phosphorylation of CREB 11/980 21/10654 5.605217574211426e-7 2.2623224721907486e-6 1.371749997260938e-6 1385/112/114/108/113/196883/115/801/111/107/109 11 Dengue_virus_type_4 R-HSA-419408 Lysosphingolipid and LPA receptors 9/980 14/10654 5.952017215074312e-7 2.3850735650369467e-6 1.4461796213951547e-6 1901/57121/9170/9294/8698/23566/1902/1903/53637 9 Dengue_virus_type_4 R-HSA-918233 TRAF3-dependent IRF activation pathway 9/980 14/10654 5.952017215074312e-7 2.3850735650369467e-6 1.4461796213951547e-6 3665/1387/2033/64135/3456/3661/29110/57506/23586 9 Dengue_virus_type_4 R-HSA-1839122 Signaling by activated point mutants of FGFR1 8/980 11/10654 6.393432539970661e-7 2.5257447278046643e-6 1.5314750067848635e-6 2246/2251/2247/2260/2254/2249/26281/8074 8 Dengue_virus_type_4 R-HSA-400451 Free fatty acids regulate insulin secretion 8/980 11/10654 6.393432539970661e-7 2.5257447278046643e-6 1.5314750067848635e-6 2864/5330/23236/2769/5331/9630/2776/2767 8 Dengue_virus_type_4 R-HSA-5603041 IRAK4 deficiency (TLR2/4) 8/980 11/10654 6.393432539970661e-7 2.5257447278046643e-6 1.5314750067848635e-6 51135/10333/7099/4615/929/7097/7096/695 8 Dengue_virus_type_4 R-HSA-8851805 MET activates RAS signaling 8/980 11/10654 6.393432539970661e-7 2.5257447278046643e-6 1.5314750067848635e-6 3082/4893/6464/3845/3265/4233/6654/2885 8 Dengue_virus_type_4 R-HSA-3858494 Beta-catenin independent WNT signaling 33/980 146/10654 8.535689637331833e-7 3.3601764135693623e-6 2.037429253684841e-6 2788/1857/10681/409/5881/51764/94235/2793/5330/1213/387/23236/54331/5880/3845/5579/2785/5331/1499/2783/2784/59345/55970/801/2782/2791/2786/2792/7976/5578/5879/2790/2787 33 Dengue_virus_type_4 R-HSA-391251 Protein folding 26/980 101/10654 9.148193382370322e-7 3.5886597198210597e-6 2.1759691738675852e-6 2788/10681/51764/94235/2793/60/54331/2785/55294/2783/2784/59345/55970/2782/6774/7157/2770/8877/2791/2786/2792/346562/2771/2773/2790/2787 26 Dengue_virus_type_4 R-HSA-3000170 Syndecan interactions 12/980 27/10654 1.6172036094726988e-6 6.321795927938732e-6 3.833195158264329e-6 3685/6383/6382/2247/2335/3690/3688/9672/87/3691/5578/3655 12 Dengue_virus_type_4 R-HSA-190373 FGFR1c ligand binding and activation 8/980 12/10654 1.7628517203477882e-6 6.863300085072371e-6 4.161533993773286e-6 2246/2251/2247/2260/2254/2249/26281/8074 8 Dengue_virus_type_4 R-HSA-163615 PKA activation 10/980 19/10654 1.7680057464229362e-6 6.863300085072371e-6 4.161533993773286e-6 112/114/108/113/196883/115/801/111/107/109 10 Dengue_virus_type_4 R-HSA-389948 PD-1 signaling 11/980 23/10654 1.80701804068712e-6 6.990471174699654e-6 4.2386436649153355e-6 3123/5777/3932/915/917/919/3122/1445/916/5781/920 11 Dengue_virus_type_4 R-HSA-1251985 Nuclear signaling by ERBB4 13/980 32/10654 2.055628190215714e-6 7.897568098491988e-6 4.788658182307542e-6 1839/685/145957/3084/5241/2066/11033/6714/2099/2069/9542/10718/6387 13 Dengue_virus_type_4 R-HSA-5673000 RAF activation 13/980 32/10654 2.055628190215714e-6 7.897568098491988e-6 4.788658182307542e-6 5518/3717/4893/3845/5604/673/3265/369/801/5894/6714/5605/5515 13 Dengue_virus_type_4 R-HSA-375165 NCAM signaling for neurite out-growth 19/980 63/10654 2.0920260548124764e-6 8.009880579727221e-6 4.856758396897026e-6 1385/64096/2674/9048/4893/4902/2260/3845/2534/5623/3265/5747/2668/6714/5594/6654/2885/5595/2675 19 Dengue_virus_type_4 R-HSA-1489509 DAG and IP3 signaling 15/980 42/10654 2.342726225153463e-6 8.939139657752804e-6 5.420210846052921e-6 1385/112/114/108/5581/113/5335/196883/115/801/111/107/109/5578/5580 15 Dengue_virus_type_4 R-HSA-1295596 Spry regulation of FGF signaling 9/980 16/10654 2.8680295633113935e-6 1.0906316502660333e-5 6.613000496858351e-6 867/5518/673/5781/6714/5594/2885/5595/5515 9 Dengue_virus_type_4 R-HSA-449836 Other interleukin signaling 11/980 24/10654 3.059602551317619e-6 1.1595375092790163e-5 7.030808360565734e-6 282618/6382/9235/3588/1436/7297/920/5803/1440/163702/3716 11 Dengue_virus_type_4 R-HSA-3000171 Non-integrin membrane-ECM interactions 18/980 59/10654 3.2199953983951135e-6 1.2162009646641003e-5 7.374384909553532e-6 284217/3685/5154/5155/6383/3918/6382/2247/3912/2335/3690/3688/9672/87/3691/4921/5578/3655 18 Dengue_virus_type_4 R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 30/980 134/10654 3.2855783103751376e-6 1.2367934515149508e-5 7.499246613083781e-6 88/3082/7414/5154/7076/6403/3479/5155/351/1893/5196/81/3827/2335/1/5579/3690/213/1950/5660/801/87/7424/5175/3674/7094/7422/5578/5054/5473 30 Dengue_virus_type_4 R-HSA-111996 Ca-dependent events 14/980 38/10654 3.3242129777240864e-6 1.2471376205018551e-5 7.5619680595348344e-6 1385/112/114/108/113/196883/115/801/111/107/109/5578/5594/5580 14 Dengue_virus_type_4 R-HSA-73887 Death Receptor Signalling 31/980 141/10654 3.391269063015228e-6 1.268039736605694e-5 7.688707187402947e-6 7409/7124/355/7128/7132/4804/10451/9138/387/4615/7186/4790/5599/5584/4803/3551/8743/3065/57580/5970/4792/356/3654/7189/9530/8878/6654/5879/7074/7410/10672 31 Dengue_virus_type_4 R-HSA-209543 p75NTR recruits signalling complexes 8/980 13/10654 4.212991213588473e-6 1.570041392263971e-5 9.519881900178866e-6 4804/4615/5584/4803/3551/3654/7189/8878 8 Dengue_virus_type_4 R-HSA-110056 MAPK3 (ERK1) activation 7/980 10/10654 5.108183992993868e-6 1.8786018763707713e-5 1.1390825801551425e-5 3717/5604/7297/5781/3569/5595/3716 7 Dengue_virus_type_4 R-HSA-190377 FGFR2b ligand binding and activation 7/980 10/10654 5.108183992993868e-6 1.8786018763707713e-5 1.1390825801551425e-5 2248/2246/2252/2247/2255/2263/27006 7 Dengue_virus_type_4 R-HSA-5602498 MyD88 deficiency (TLR2/4) 7/980 10/10654 5.108183992993868e-6 1.8786018763707713e-5 1.1390825801551425e-5 10333/7099/4615/929/7097/7096/695 7 Dengue_virus_type_4 R-HSA-8875656 MET receptor recycling 7/980 10/10654 5.108183992993868e-6 1.8786018763707713e-5 1.1390825801551425e-5 3082/382/2549/1399/4233/2885/1398 7 Dengue_virus_type_4 R-HSA-164378 PKA activation in glucagon signalling 9/980 17/10654 5.597230398023799e-6 2.0517060934395435e-5 1.2440436156435985e-5 112/114/108/113/196883/115/111/107/109 9 Dengue_virus_type_4 R-HSA-5621575 CD209 (DC-SIGN) signaling 10/980 21/10654 5.685302288696173e-6 2.077179071490955e-5 1.2594890519161802e-5 1387/4067/4893/4790/3845/2534/2033/3265/5970/5894 10 Dengue_virus_type_4 R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 8/980 14/10654 9.036710536363248e-6 3.2908932832749546e-5 1.9954197104124572e-5 4893/387/9564/3845/3265/5829/5879/1398 8 Dengue_virus_type_4 R-HSA-111933 Calmodulin induced events 13/980 36/10654 9.642933884283028e-6 3.477677446009169e-5 2.108675525119956e-5 1385/112/114/108/113/196883/115/801/111/107/109/5578/5580 13 Dengue_virus_type_4 R-HSA-111997 CaM pathway 13/980 36/10654 9.642933884283028e-6 3.477677446009169e-5 2.108675525119956e-5 1385/112/114/108/113/196883/115/801/111/107/109/5578/5580 13 Dengue_virus_type_4 R-HSA-1266695 Interleukin-7 signaling 13/980 36/10654 9.642933884283028e-6 3.477677446009169e-5 2.108675525119956e-5 5295/3082/8660/8503/5296/3667/6597/3561/3574/6774/3718/8651/3716 13 Dengue_virus_type_4 R-HSA-114608 Platelet degranulation 28/980 129/10654 1.2904997949434712e-5 4.632768144235399e-5 2.8090600554444933e-5 88/3082/7414/5154/7076/6403/3479/5155/351/1893/5196/81/3827/2335/1/3690/213/1950/5660/801/87/7424/5175/3674/7094/7422/5054/5473 28 Dengue_virus_type_4 R-HSA-2586552 Signaling by Leptin 7/980 11/10654 1.292865528623832e-5 4.632768144235399e-5 2.8090600554444933e-5 8660/3717/3952/3667/5781/6774/9021 7 Dengue_virus_type_4 R-HSA-9614085 FOXO-mediated transcription 18/980 65/10654 1.4552248010578895e-5 5.197895615280257e-5 3.1517227909240996e-5 8850/604/1387/4088/2908/7534/10000/6794/2033/2309/4852/3630/3065/356/5443/207/4087/208 18 Dengue_virus_type_4 R-HSA-2559583 Cellular Senescence 37/980 195/10654 1.529096582944023e-5 5.444362992775215e-5 3.301167279302551e-5 2353/51343/3552/1432/3725/1051/25906/79813/3576/11065/8881/4790/29882/5599/119504/5600/246184/1029/3456/7321/6774/3569/7157/5970/51529/7324/64682/6667/29945/10393/8697/10919/5594/996/5595/51434/51433 37 Dengue_virus_type_4 R-HSA-193704 p75 NTR receptor-mediated signalling 23/980 97/10654 1.684654071858633e-5 5.97918492805699e-5 3.625454376865363e-5 7409/4804/10451/9138/387/4615/4790/5599/5584/4803/3551/3065/57580/5970/4792/3654/7189/8878/6654/5879/7074/7410/10672 23 Dengue_virus_type_4 R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 8/980 15/10654 1.780282301993208e-5 6.298593714013945e-5 3.819126590551718e-5 54106/51135/3665/4615/3654/7189/51284/51311 8 Dengue_virus_type_4 R-HSA-202430 Translocation of ZAP-70 to Immunological synapse 9/980 19/10654 1.794421161016175e-5 6.328589457463986e-5 3.837314387163927e-5 3123/3932/915/917/919/3122/916/920/7535 9 Dengue_virus_type_4 R-HSA-202424 Downstream TCR signaling 23/980 98/10654 2.013227926984354e-5 7.07795227159908e-5 4.291687470963006e-5 5295/3123/5170/3932/3635/915/5588/5290/5296/917/4790/919/5291/5728/3122/3551/916/7321/920/5970/4792/50852/7189 23 Dengue_virus_type_4 R-HSA-373752 Netrin-1 signaling 15/980 50/10654 2.645052172272583e-5 9.270120152353441e-5 5.620899518045021e-5 1432/116986/5588/5335/219699/9423/5599/2534/5600/5747/4690/5781/998/6714/5879 15 Dengue_virus_type_4 R-HSA-381771 Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) 9/980 20/10654 2.9970896067182127e-5 1.0471081813471756e-4 6.34909771949516e-5 2864/51764/2922/3952/338557/1499/2641/2784/346562 9 Dengue_virus_type_4 R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 21/980 88/10654 3.503336681755479e-5 1.2201652368232478e-4 7.398422111987305e-5 5393/1432/11340/7534/51010/5600/56915/8570/23404/51013/5073/6418/23016/207/54512/8741/118460/167227/5578/22894/5580 21 Dengue_virus_type_4 R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 17/980 63/10654 3.617102280209884e-5 1.255875884867904e-4 7.614952168862915e-5 51343/25906/11065/8881/29882/119504/246184/7321/51529/7324/64682/29945/10393/8697/996/51434/51433 17 Dengue_virus_type_4 R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 10/980 25/10654 3.7402809541746984e-5 1.2946235624666604e-4 7.84989713048234e-5 2475/7249/1385/5170/2932/10000/2309/842/207/208 10 Dengue_virus_type_4 R-HSA-450294 MAP kinase activation 17/980 64/10654 4.509568658344446e-5 1.556079555564534e-4 9.435224873209302e-5 1385/2353/1432/3725/5518/1386/4790/5599/5600/3656/5604/3551/3654/7189/5594/5595/5515 17 Dengue_virus_type_4 R-HSA-373755 Semaphorin interactions 17/980 65/10654 5.591315441133462e-5 1.923412511749911e-4 1.1662533260210363e-4 2932/23396/2064/387/3320/2534/3688/7305/3672/54209/6237/1020/4233/4628/7094/5879/2242 17 Dengue_virus_type_4 R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 11/980 31/10654 5.67441633691536e-5 1.941725159196935e-4 1.1773571250567987e-4 1385/2353/1432/3725/5518/1386/5599/5600/5594/5595/5515 11 Dengue_virus_type_4 R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 7/980 13/10654 5.696653418753083e-5 1.941725159196935e-4 1.1773571250567987e-4 2064/10000/3084/2065/207/208/9542 7 Dengue_virus_type_4 R-HSA-5658623 FGFRL1 modulation of FGFR1 signaling 7/980 13/10654 5.696653418753083e-5 1.941725159196935e-4 1.1773571250567987e-4 2248/8817/2247/2255/27006/2249/8074 7 Dengue_virus_type_4 R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 18/980 72/10654 6.516760942911546e-5 2.2077996164166993e-4 1.3386902861993734e-4 51343/25906/11065/8881/29882/119504/246184/7321/51529/7324/64682/29945/10393/8697/9232/996/51434/51433 18 Dengue_virus_type_4 R-HSA-448424 Interleukin-17 signaling 18/980 72/10654 6.516760942911546e-5 2.2077996164166993e-4 1.3386902861993734e-4 3605/1385/2353/1432/3725/5518/1386/4790/5599/5600/3656/5604/3551/3654/7189/5594/5595/5515 18 Dengue_virus_type_4 R-HSA-202427 Phosphorylation of CD3 and TCR zeta chains 9/980 22/10654 7.492113565827066e-5 2.530568872082979e-4 1.5344001069780985e-4 3123/3932/915/917/919/3122/1445/916/920 9 Dengue_virus_type_4 R-HSA-164952 The role of Nef in HIV-1 replication and disease pathogenesis 10/980 27/10654 8.136902226550805e-5 2.7400773160493375e-4 1.6614346968607226e-4 3932/919/2534/375/920/567/3055/926/940/5879 10 Dengue_virus_type_4 R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 17/980 67/10654 8.461073551566337e-5 2.8406847539492986e-4 1.7224376061984262e-4 25906/11065/8881/29882/119504/246184/7321/51529/7324/64682/29945/10393/8697/9232/996/51434/51433 17 Dengue_virus_type_4 R-HSA-418885 DCC mediated attractive signaling 7/980 14/10654 1.0489635783869878e-4 3.5112014390318934e-4 2.1290026614598809e-4 9423/2534/5747/4690/998/6714/5879 7 Dengue_virus_type_4 R-HSA-112409 RAF-independent MAPK1/3 activation 9/980 23/10654 1.1309788185921925e-4 3.763197378529974e-4 2.2817993708438975e-4 3717/5604/7297/5781/3569/5594/5605/5595/3716 9 Dengue_virus_type_4 R-HSA-400508 Incretin synthesis, secretion, and inactivation 9/980 23/10654 1.1309788185921925e-4 3.763197378529974e-4 2.2817993708438975e-4 2864/51764/2922/3952/338557/1499/2641/2784/346562 9 Dengue_virus_type_4 R-HSA-447115 Interleukin-12 family signaling 15/980 57/10654 1.4038255453926348e-4 4.6572016609761595e-4 2.823875218593962e-4 149233/5908/3594/3717/3592/51561/375/3458/7297/998/6774/3593/3586/6772/3716 15 Dengue_virus_type_4 R-HSA-3928664 Ephrin signaling 8/980 19/10654 1.4953247210441366e-4 4.946074077299837e-4 2.99903182918849e-4 2050/2047/2534/1947/1948/6714/2048/5879 8 Dengue_virus_type_4 R-HSA-6783589 Interleukin-6 family signaling 9/980 24/10654 1.6628892359832738e-4 5.484100784157227e-4 3.3252621269157847e-4 867/3717/7297/5781/6774/3569/9021/6772/3716 9 Dengue_virus_type_4 R-HSA-5675221 Negative regulation of MAPK pathway 12/980 40/10654 1.6843047978612057e-4 5.538390482378906e-4 3.35818046384711e-4 5518/4893/3845/5604/673/3265/369/5894/5594/5605/5595/5515 12 Dengue_virus_type_4 R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 17/980 72/10654 2.1917228738515068e-4 7.185765903126055e-4 4.3570598263941053e-4 51343/25906/11065/8881/29882/119504/246184/7321/51529/7324/64682/29945/10393/8697/996/51434/51433 17 Dengue_virus_type_4 R-HSA-3928663 EPHA-mediated growth cone collapse 10/980 30/10654 2.243926259932619e-4 7.314022036748303e-4 4.4348274095338554e-4 4067/387/2534/2046/1946/4628/1969/6714/7525/1942 10 Dengue_virus_type_4 R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 10/980 30/10654 2.243926259932619e-4 7.314022036748303e-4 4.4348274095338554e-4 88/1385/5170/4893/3845/3265/801/5594/1739/5595 10 Dengue_virus_type_4 R-HSA-8876384 Listeria monocytogenes entry into host cells 8/980 20/10654 2.2924018946256824e-4 7.450306157533468e-4 4.517462729923316e-4 867/999/1499/1500/4233/6714/30011/2885 8 Dengue_virus_type_4 R-HSA-8856828 Clathrin-mediated endocytosis 27/980 146/10654 3.2416923699136996e-4 0.001050496252047396 6.369641147900602e-4 5869/409/1080/23396/867/1759/382/1213/1839/1956/915/685/60/917/1129/408/5868/51429/1950/6869/920/551/185/8871/2069/30011/2885 27 Dengue_virus_type_4 R-HSA-373080 Class B/2 (Secretin family receptors) 20/980 95/10654 3.330075933473984e-4 0.0010760187553826342 6.52439580516351e-4 2788/10681/51764/94235/2793/2642/54331/2785/2783/2641/2784/59345/55970/2782/2791/2786/2792/7976/2790/2787 20 Dengue_virus_type_4 R-HSA-8984722 Interleukin-35 Signalling 6/980 12/10654 3.3892426395411784e-4 0.0010919807697426622 6.621180827740085e-4 3717/3592/7297/6774/6772/3716 6 Dengue_virus_type_4 R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 8/980 21/10654 3.4065871134658085e-4 0.0010944150554180385 6.63594101957647e-4 4615/7098/4790/3551/5970/4792/3661/29110 8 Dengue_virus_type_4 R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 17/980 75/10654 3.685163045812115e-4 0.0011805192794320757 7.158030467510185e-4 25906/11065/8881/29882/119504/246184/7321/51529/7324/64682/29945/10393/8697/9232/996/51434/51433 17 Dengue_virus_type_4 R-HSA-9020702 Interleukin-1 signaling 21/980 103/10654 3.789478400234784e-4 0.0012104676718464253 7.339621322560002e-4 51135/3557/3552/351/4615/4790/3656/5604/11213/3551/6288/5970/4792/3654/7189/3554/3553/8878/54472/3146/3556 21 Dengue_virus_type_4 R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 17/980 76/10654 4.3481115597166463e-4 0.001384954052354191 8.397612369043396e-4 25906/11065/8881/29882/119504/246184/7321/51529/7324/64682/29945/10393/8697/9232/996/51434/51433 17 Dengue_virus_type_4 R-HSA-5689896 Ovarian tumor domain proteases 11/980 38/10654 4.423228862534867e-4 0.0014048778034982902 8.51841922091045e-4 7128/387/10318/64135/5728/7321/7157/7189/2099/57506/23586 11 Dengue_virus_type_4 R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 9/980 27/10654 4.628099773593251e-4 0.0014657834410417153 8.887718068269132e-4 355/7099/929/7186/219699/842/26060/8743/356 9 Dengue_virus_type_4 R-HSA-432142 Platelet sensitization by LDL 7/980 17/10654 4.642440311095818e-4 0.0014661718270635945 8.890073031060681e-4 1432/5777/5518/5781/5175/5515/2268 7 Dengue_virus_type_4 R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 8/980 22/10654 4.925087545970456e-4 0.00154669884168398 9.378345297471833e-4 3725/351/994/2309/993/1020/356/823 8 Dengue_virus_type_4 R-HSA-8863678 Neurodegenerative Diseases 8/980 22/10654 4.925087545970456e-4 0.00154669884168398 9.378345297471833e-4 3725/351/994/2309/993/1020/356/823 8 Dengue_virus_type_4 R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 10/980 33/10654 5.356761433615516e-4 0.001677551619826932 0.0010171765776937616 351/4790/3656/3551/6288/5970/4792/3654/7189/3146 10 Dengue_virus_type_4 R-HSA-171007 p38MAPK events 6/980 13/10654 5.806023180397644e-4 0.0018131658982359123 0.001099405741892409 1432/4893/3845/5600/3265/6714 6 Dengue_virus_type_4 R-HSA-112316 Neuronal System 58/980 413/10654 6.830779514959955e-4 0.0021272455425418468 0.0012898466522897555 2788/88/2036/10681/1385/51764/112/5170/5563/94235/114/2793/5330/4893/108/23236/54331/3084/113/3845/196883/5579/54413/2785/5331/115/3265/2783/2784/59345/55970/801/2782/2770/111/107/2066/2791/9568/2786/109/2915/2792/2550/346562/5578/2771/2773/4916/6714/5594/2911/5879/1739/5595/2790/2787/3556 58 Dengue_virus_type_4 R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 16/980 72/10654 6.856680445243867e-4 0.002129380204939623 0.0012911409961219446 25906/11065/8881/29882/119504/246184/7321/51529/7324/64682/29945/10393/8697/996/51434/51433 16 Dengue_virus_type_4 R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 18/980 86/10654 6.989829375115376e-4 0.0021587373594969587 0.0013089415869654848 51343/25906/11065/8881/29882/119504/246184/7321/51529/7324/64682/29945/10393/8697/9232/996/51434/51433 18 Dengue_virus_type_4 R-HSA-453276 Regulation of mitotic cell cycle 18/980 86/10654 6.989829375115376e-4 0.0021587373594969587 0.0013089415869654848 51343/25906/11065/8881/29882/119504/246184/7321/51529/7324/64682/29945/10393/8697/9232/996/51434/51433 18 Dengue_virus_type_4 R-HSA-381119 Unfolded Protein Response (UPR) 19/980 94/10654 7.904438939346538e-4 0.0024344800920632036 0.0014761370674029781 5393/6347/1051/11340/6464/3576/51010/468/56915/8570/23404/51013/5073/23016/54512/7094/118460/167227/22894 19 Dengue_virus_type_4 R-HSA-109606 Intrinsic Pathway for Apoptosis 13/980 53/10654 8.028905644759894e-4 0.002464762020917485 0.0014944983913669715 7533/598/7534/10000/5599/1029/842/6774/7157/207/5594/208/5595 13 Dengue_virus_type_4 R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 16/980 73/10654 8.046852751653685e-4 0.002464762020917485 0.0014944983913669715 25906/11065/8881/29882/119504/246184/7321/51529/7324/64682/29945/10393/8697/996/51434/51433 16 Dengue_virus_type_4 R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 17/980 80/10654 8.130056444115838e-4 0.0024834434711807395 0.0015058258124850733 51343/25906/11065/8881/29882/119504/246184/7321/51529/7324/64682/29945/10393/8697/996/51434/51433 17 Dengue_virus_type_4 R-HSA-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 24/980 132/10654 8.755072580722465e-4 0.0026670766063345273 0.0016171710144802147 930/3824/3133/2209/3383/915/999/925/917/919/958/3688/7305/2214/54209/916/7412/933/567/10870/3105/926/959/718 24 Dengue_virus_type_4 R-HSA-198323 AKT phosphorylates targets in the cytosol 6/980 14/10654 9.37381788190565e-4 0.002840088995113961 0.0017220763702602306 7249/2932/10000/842/207/208 6 Dengue_virus_type_4 R-HSA-399955 SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion 6/980 14/10654 9.37381788190565e-4 0.002840088995113961 0.0017220763702602306 23396/2534/6237/7094/5879/2242 6 Dengue_virus_type_4 R-HSA-438064 Post NMDA receptor activation events 17/980 81/10654 9.426907196339327e-4 0.002848454660947937 0.0017271488575938908 88/1385/5170/5563/114/4893/3084/3845/3265/801/107/2066/6714/5594/5879/1739/5595 17 Dengue_virus_type_4 R-HSA-5686938 Regulation of TLR by endogenous ligand 7/980 19/10654 0.0010207468339790003 0.0030759971978127285 0.00186511834609867 10333/7099/929/7097/7096/6279/3146 7 Dengue_virus_type_4 R-HSA-6804758 Regulation of TP53 Activity through Acetylation 9/980 30/10654 0.0010978648769463914 0.0032906512933674682 0.0019952729808197438 79837/5305/10000/2033/3065/7157/207/208/8396 9 Dengue_virus_type_4 R-HSA-8874081 MET activates PTK2 signaling 9/980 30/10654 0.0010978648769463914 0.0032906512933674682 0.0019952729808197438 3082/284217/3918/3912/2335/3688/5747/4233/6714 9 Dengue_virus_type_4 R-HSA-9020958 Interleukin-21 signaling 5/980 10/10654 0.0011077141463847694 0.003311295229032546 0.002007790346951285 3561/6774/3718/6772/3716 5 Dengue_virus_type_4 R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 10/980 36/10654 0.0011407444016833406 0.0033918942581967417 0.002056661239317109 60/5747/4690/10006/998/695/5594/5879/2885/5595 10 Dengue_virus_type_4 R-HSA-6804757 Regulation of TP53 Degradation 10/980 36/10654 0.0011407444016833406 0.0033918942581967417 0.002056661239317109 2475/5170/5518/10000/1029/6446/7157/207/208/5515 10 Dengue_virus_type_4 R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 13/980 55/10654 0.0011653488047134843 0.0034558619725986086 0.0020954478018581153 7128/834/1432/351/598/4790/5600/3656/3551/842/5970/3654/7189 13 Dengue_virus_type_4 R-HSA-429914 Deadenylation-dependent mRNA decay 13/980 56/10654 0.0013923666077279323 0.004116297391770869 0.0024959001226818934 5393/11340/51010/56915/23404/51013/5073/23016/54512/118460/167227/22894/4849 13 Dengue_virus_type_4 R-HSA-446728 Cell junction organization 18/980 91/10654 0.0013954174521298383 0.004116297391770869 0.0024959001226818934 1003/3918/999/60/50848/3688/7408/1495/1499/3728/5584/1500/3611/87/1000/3691/5829/3655 18 Dengue_virus_type_4 R-HSA-182971 EGFR downregulation 9/980 31/10654 0.0014225356427342102 0.004185249601518019 0.0025377090136311123 867/1839/1956/685/1950/998/2069/30011/2885 9 Dengue_virus_type_4 R-HSA-6806003 Regulation of TP53 Expression and Degradation 10/980 37/10654 0.0014364404896893793 0.004215066843760436 0.0025557885767646367 2475/5170/5518/10000/1029/6446/7157/207/208/5515 10 Dengue_virus_type_4 R-HSA-75892 Platelet Adhesion to exposed collagen 6/980 15/10654 0.001441567513114195 0.004219037904873481 0.002558196413462501 4067/2534/3688/3672/2207/51206 6 Encephalomyocarditis_virus R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 109/785 112/10654 4.337147821610333e-122 4.883628447133235e-119 2.574896180408661e-119 6142/6158/6167/7458/7311/8669/6204/6223/25873/8664/6224/6146/3646/8662/6138/51065/6154/6141/10480/6144/8663/6202/6228/23521/6123/6203/51386/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/8894/6134/1965/6169/6160/6234/27335/6191/8665/6166/6128/6135/6201/6164/1981/140801/6161/51121/6132/6156/6155/6159/6147/8661/6175/8666/6235/6129/6218/6143/1973/9045/6217/6181/6187/6124/9669/6168/6207/6208/6222/6157/6137/1983/6176/6170/6209/1977/6139/6152/1974/200916/6136/1964/6193/6122/6173/6133/6210/6231/6229/11224/6205/8668/6233/1975/6165/1968/8667/6125/6230/6130 109 Encephalomyocarditis_virus R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 108/785 111/10654 6.5735035022204745e-121 3.7008824717501272e-118 1.9512926185538673e-118 6142/6158/6167/7458/7311/8669/6204/6223/25873/8664/6224/6146/3646/8662/6138/51065/6154/6141/10480/6144/26986/8663/6202/6228/23521/6123/6203/51386/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/8894/6134/1965/6169/6160/6234/27335/6191/8665/6166/6128/6135/6201/6164/1981/140801/6161/51121/6132/6156/6155/6159/6147/8661/6175/8666/6235/6129/6218/6143/1973/9045/6217/6181/6187/6124/6168/6207/6208/6222/6157/6137/6176/6170/6209/1977/6139/6152/1974/200916/6136/1964/6193/6122/6173/6133/6210/6231/6229/11224/6205/8668/6233/1975/6165/1968/8667/6125/6230/6130 108 Encephalomyocarditis_virus R-HSA-72613 Eukaryotic Translation Initiation 111/785 119/10654 4.41677606837046e-118 1.2433224632462843e-115 6.555425533055103e-116 6142/6158/6167/7458/7311/8669/6204/6223/25873/8664/6224/6146/3646/8662/6138/51065/6154/6141/10480/6144/26986/8663/6202/6228/23521/6123/6203/51386/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/8894/6134/1965/6169/6160/6234/27335/6191/8665/6166/6128/6135/6201/6164/1978/1981/140801/6161/51121/6132/6156/6155/6159/6147/8661/6175/8666/6235/6129/6218/6143/1973/9045/6217/6181/6187/6124/9669/6168/6207/6208/6222/6157/6137/1983/6176/6170/6209/1977/6139/6152/1974/200916/6136/1964/6193/6122/6173/6133/6210/6231/6229/11224/6205/8668/6233/1975/6165/1968/8667/6125/6230/6130 111 Encephalomyocarditis_virus R-HSA-72737 Cap-dependent Translation Initiation 111/785 119/10654 4.41677606837046e-118 1.2433224632462843e-115 6.555425533055103e-116 6142/6158/6167/7458/7311/8669/6204/6223/25873/8664/6224/6146/3646/8662/6138/51065/6154/6141/10480/6144/26986/8663/6202/6228/23521/6123/6203/51386/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/8894/6134/1965/6169/6160/6234/27335/6191/8665/6166/6128/6135/6201/6164/1978/1981/140801/6161/51121/6132/6156/6155/6159/6147/8661/6175/8666/6235/6129/6218/6143/1973/9045/6217/6181/6187/6124/9669/6168/6207/6208/6222/6157/6137/1983/6176/6170/6209/1977/6139/6152/1974/200916/6136/1964/6193/6122/6173/6133/6210/6231/6229/11224/6205/8668/6233/1975/6165/1968/8667/6125/6230/6130 111 Encephalomyocarditis_virus R-HSA-72689 Formation of a pool of free 40S subunits 98/785 101/10654 3.842610441381085e-109 8.653558713990203e-107 4.5625942925030146e-107 6142/6158/6167/7311/8669/6204/6223/25873/8664/6224/6146/3646/8662/6138/51065/6154/6141/10480/6144/8663/6202/6228/23521/6123/6203/51386/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/6134/6169/6160/6234/27335/6191/8665/6166/6128/6135/6201/6164/140801/6161/51121/6132/6156/6155/6159/6147/8661/6175/8666/6235/6129/6218/6143/9045/6217/6181/6187/6124/6168/6207/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/1964/6193/6122/6173/6133/6210/6231/6229/11224/6205/8668/6233/6165/8667/6125/6230/6130 98 Encephalomyocarditis_virus R-HSA-168255 Influenza Life Cycle 115/785 144/10654 5.104841920568125e-105 9.580086670932849e-103 5.051106742456882e-103 6142/6158/7514/6167/23165/7311/6204/6223/3303/25873/9883/9972/6224/6146/348995/6138/51065/6154/6141/6144/6202/6228/79023/23521/6123/81929/6203/1213/57122/23636/116832/5903/6227/9349/23225/4736/3921/6188/6189/6232/8021/6206/6194/6134/3320/6169/10762/6160/6234/6191/55706/7175/6166/6128/6135/6201/129401/23511/6164/140801/6161/51121/6132/9631/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/53371/6181/6187/6124/5901/55746/6168/6207/6208/6222/8086/6157/6137/6176/6170/6209/6139/6152/200916/6136/8480/6193/6122/6173/6133/23279/6210/4927/6231/6229/9688/11224/6205/6233/6165/6125/79902/821/6230/6130 115 Encephalomyocarditis_virus R-HSA-168273 Influenza Viral RNA Transcription and Replication 110/785 134/10654 6.22068735347738e-103 1.0006419942879329e-100 5.275891229114651e-101 6142/6158/6167/23165/7311/6204/6223/25873/9883/9972/6224/6146/348995/6138/51065/6154/6141/6144/6202/6228/79023/23521/6123/81929/6203/57122/23636/116832/5903/6227/9349/23225/4736/3921/6188/6189/6232/8021/6206/6194/6134/3320/6169/10762/6160/6234/6191/55706/7175/6166/6128/6135/6201/129401/23511/6164/140801/6161/51121/6132/9631/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/53371/6181/6187/6124/55746/6168/6207/6208/6222/8086/6157/6137/6176/6170/6209/6139/6152/200916/6136/8480/6193/6122/6173/6133/23279/6210/4927/6231/6229/9688/11224/6205/6233/6165/6125/79902/6230/6130 110 Encephalomyocarditis_virus R-HSA-168254 Influenza Infection 117/785 155/10654 1.2386814369578894e-101 1.7434441225182293e-99 9.192320137424338e-100 6142/6158/7514/6167/23165/7311/6204/6223/3303/25873/9883/9972/6224/6146/348995/6138/51065/6154/6141/9636/6144/6202/6228/79023/23521/6123/81929/6203/1213/57122/23636/5610/116832/5903/6227/9349/23225/4736/3921/6188/6189/6232/8021/6206/6194/6134/3320/6169/10762/6160/6234/6191/55706/7175/6166/6128/6135/6201/129401/23511/6164/140801/6161/51121/6132/9631/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/53371/6181/6187/6124/5901/55746/6168/6207/6208/6222/8086/6157/6137/6176/6170/6209/6139/6152/200916/6136/8480/6193/6122/6173/6133/23279/6210/4927/6231/6229/9688/11224/6205/6233/6165/6125/79902/821/6230/6130 117 Encephalomyocarditis_virus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 90/785 95/10654 3.448333787128349e-97 4.3142487158961347e-95 2.2746903578250165e-95 6142/6158/6167/7311/6204/6223/25873/6224/6146/6138/51065/6154/6141/6144/26986/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/2935/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/1981/140801/6161/51121/4686/6132/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/5976/6217/6181/6187/6124/6168/6207/22916/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/6233/6165/6125/6230/6130 90 Encephalomyocarditis_virus R-HSA-156902 Peptide chain elongation 85/785 89/10654 1.2339225932047396e-92 1.3893968399485368e-90 7.325603605973402e-91 6142/6158/6167/7311/6204/6223/25873/6224/6146/6138/51065/6154/6141/6144/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/140801/6161/51121/6132/6156/6155/1938/6159/6147/6175/6235/6129/6218/6143/9045/6217/6181/6187/6124/6168/6207/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/6233/6165/6125/6230/6130 85 Encephalomyocarditis_virus R-HSA-156842 Eukaryotic Translation Elongation 86/785 93/10654 2.589391799653446e-90 2.6505956058270726e-88 1.397528205745975e-88 6142/6158/6167/7311/6204/6223/25873/6224/6146/6138/51065/6154/6141/6144/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/140801/6161/51121/6132/6156/6155/1938/6159/6147/6175/6235/6129/6218/6143/9045/6217/6181/6187/6124/1936/6168/6207/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/6233/6165/6125/6230/6130 86 Encephalomyocarditis_virus R-HSA-192823 Viral mRNA Translation 84/785 89/10654 2.9546028803665704e-90 2.7724023694106317e-88 1.4617508987076716e-88 6142/6158/6167/7311/6204/6223/25873/6224/6146/6138/51065/6154/6141/6144/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/140801/6161/51121/6132/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/6181/6187/6124/6168/6207/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/6233/6165/6125/6230/6130 84 Encephalomyocarditis_virus R-HSA-72764 Eukaryotic Translation Termination 85/785 93/10654 3.92524049697212e-88 3.399862153531236e-86 1.792579465823705e-86 6142/6158/6167/7311/6204/6223/25873/6224/6146/6138/51065/6154/6141/6144/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/2935/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/140801/6161/51121/6132/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/6181/6187/6124/6168/6207/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/6233/6165/6125/6230/6130 85 Encephalomyocarditis_virus R-HSA-2408557 Selenocysteine synthesis 84/785 93/10654 5.2197466390776225e-86 4.198167654001002e-84 2.2134865446915635e-84 6142/6158/6167/7311/6204/6223/25873/6224/6146/6138/51065/6154/6141/6144/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/140801/6161/51121/6132/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/6181/6187/6124/6168/6207/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/6233/6165/6125/6230/6130 84 Encephalomyocarditis_virus R-HSA-927802 Nonsense-Mediated Decay (NMD) 92/785 115/10654 6.988196138598151e-84 4.917943032538449e-82 2.5929885672166826e-82 6142/6158/6167/7311/6204/6223/25873/6224/6146/6138/51065/6154/6141/6144/26986/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/9775/6206/6194/2935/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/1981/140801/6161/51121/4686/6132/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/5976/6217/6181/6187/6124/6168/6207/22916/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/6233/6165/5515/6125/6230/6130 92 Encephalomyocarditis_virus R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 92/785 115/10654 6.988196138598151e-84 4.917943032538449e-82 2.5929885672166826e-82 6142/6158/6167/7311/6204/6223/25873/6224/6146/6138/51065/6154/6141/6144/26986/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/9775/6206/6194/2935/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/1981/140801/6161/51121/4686/6132/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/5976/6217/6181/6187/6124/6168/6207/22916/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/6233/6165/5515/6125/6230/6130 92 Encephalomyocarditis_virus R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 85/785 112/10654 6.841293090968132e-74 4.531350600253009e-72 2.389157463347385e-72 6142/6158/6167/7311/6204/6223/25873/6224/6146/6138/51065/6154/6141/6144/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/6134/6747/6169/6160/6234/6191/6166/6128/6135/6201/6164/140801/6161/51121/6132/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/6181/6187/6124/6168/6207/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/6233/6165/6125/6230/6130 85 Encephalomyocarditis_virus R-HSA-2408522 Selenoamino acid metabolism 84/785 118/10654 4.757189625218589e-69 2.97588639888674e-67 1.5690379816510433e-67 6142/6158/6167/7311/6204/6223/25873/6224/6146/6138/51065/6154/6141/6144/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/140801/6161/51121/6132/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/6181/6187/6124/6168/6207/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/6233/6165/6125/6230/6130 84 Encephalomyocarditis_virus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 95/785 171/10654 3.9446715019046854e-63 2.3377369006024608e-61 1.2325732559968105e-61 5716/6142/6158/6167/7311/6204/6223/25873/6224/6146/6138/51065/6154/6141/6144/26986/6202/6228/23032/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/9775/6206/6194/2935/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/1981/140801/6161/51121/4686/6132/6156/7316/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/6181/6187/6124/6168/6207/22916/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/7314/5704/6233/6165/6125/6230/6130 95 Encephalomyocarditis_virus R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 57/785 59/10654 5.916966047909731e-63 3.3312518849731786e-61 1.7564046584321522e-61 7458/8669/6204/6223/8664/6224/3646/8662/51065/10480/26986/8663/6202/6228/6203/51386/6227/3921/6188/6189/6232/6206/6194/8894/1965/6234/27335/6191/8665/6201/1978/1981/8661/8666/6235/6218/1973/6217/6187/6207/6208/6222/6209/1977/1974/1964/6193/6210/6231/6229/6205/8668/6233/1975/1968/8667/6230 57 Encephalomyocarditis_virus R-HSA-5663205 Infectious disease 139/785 383/10654 1.4120829304588237e-62 7.571454189031597e-61 3.992053998891111e-61 5716/6142/6500/6158/7514/6167/1025/23165/7311/23327/6204/6223/3303/25873/9883/9972/6224/6146/348995/6138/51065/6154/8945/6141/9636/6144/6202/6228/79023/23521/6123/81929/6203/1213/57122/23636/5610/116832/5903/6227/9349/23225/4736/999/3921/6188/6189/6232/8021/6206/6194/6134/3320/6169/10762/6160/6234/6191/55706/7175/6166/6128/6135/6201/129401/23511/6164/5606/140801/6161/51121/4686/6132/9631/6156/7316/1499/6155/1938/6159/6147/6175/6235/6129/6218/6143/2547/9045/6217/53371/6181/6187/6124/5608/5901/55746/6168/6207/22916/6208/6222/8086/6157/51534/6137/6176/6170/6209/6139/6152/200916/6136/8480/6193/6122/6714/6173/6133/23279/6210/4927/5609/6231/6229/9688/11224/6205/7314/5704/7520/6233/6165/8731/6125/3326/79902/821/6230/6130 139 Encephalomyocarditis_virus R-HSA-72649 Translation initiation complex formation 56/785 58/10654 8.309162798345537e-62 4.067877091711772e-60 2.144790763508871e-60 7458/8669/6204/6223/8664/6224/3646/8662/51065/10480/26986/8663/6202/6228/6203/51386/6227/3921/6188/6189/6232/6206/6194/8894/1965/6234/27335/6191/8665/6201/1981/8661/8666/6235/6218/1973/6217/6187/6207/6208/6222/6209/1977/1974/1964/6193/6210/6231/6229/6205/8668/6233/1975/1968/8667/6230 56 Encephalomyocarditis_virus R-HSA-72702 Ribosomal scanning and start codon recognition 56/785 58/10654 8.309162798345537e-62 4.067877091711772e-60 2.144790763508871e-60 7458/8669/6204/6223/8664/6224/3646/8662/51065/10480/8663/6202/6228/6203/51386/6227/3921/6188/6189/6232/6206/6194/8894/1965/6234/27335/6191/8665/6201/1981/8661/8666/6235/6218/1973/6217/6187/6207/6208/6222/1983/6209/1977/1974/1964/6193/6210/6231/6229/6205/8668/6233/1975/1968/8667/6230 56 Encephalomyocarditis_virus R-HSA-168898 Toll-like Receptor Cascades 87/785 155/10654 2.6577238505238423e-58 1.2469154398707693e-56 6.574369524980032e-57 7322/54106/8454/6500/23643/51135/1147/64127/330/3665/7311/1432/3725/11035/8945/23118/1326/329/246330/7187/1386/351/23291/10333/841/7099/8517/8772/4615/81793/929/9641/7098/4790/114609/6885/5599/353376/5600/5528/5606/3656/7334/7316/6195/7097/57162/3551/79155/10454/7321/5781/30849/5608/8737/10392/7335/5970/4792/8767/7096/5289/57161/3661/9261/695/59307/4793/3654/6279/4791/29110/7189/5594/5609/51284/7314/6233/5595/51311/10010/5515/148022/3146/7867/257397/4214 87 Encephalomyocarditis_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 79/785 129/10654 4.5785060597456904e-57 2.062159129309459e-55 1.0872747021880292e-55 7322/8454/6500/23643/51135/1147/64127/330/3665/7311/1432/3725/11035/8945/23118/1326/329/246330/7187/1386/351/23291/10333/841/7099/8517/8772/4615/929/9641/4790/114609/6885/5599/353376/5600/5528/5606/3656/7334/7316/6195/7097/57162/3551/79155/10454/7321/5781/5608/8737/10392/7335/5970/4792/8767/7096/57161/3661/9261/695/59307/4793/3654/4791/29110/7189/5594/5609/7314/6233/5595/10010/5515/148022/3146/7867/257397/4214 79 Encephalomyocarditis_virus R-HSA-72766 Translation 116/785 291/10654 4.815818846409383e-57 2.0856200080988328e-55 1.0996444653339644e-55 6142/6158/6167/7458/7311/8669/6204/6223/25873/8664/6224/6146/3646/8662/6138/51065/6154/6141/10480/6144/26986/8663/6202/6228/23521/6123/6203/51386/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/8894/2935/6134/1965/6747/6169/6160/6234/27335/6191/8665/6166/6128/6135/6201/6164/1978/1981/140801/6161/51121/6132/6156/6155/1938/6159/6147/8661/6175/8666/6235/6129/6218/6143/1973/9045/6217/6181/6187/6124/1936/9669/6168/6207/6208/6222/6157/6137/1983/6176/6170/7284/6209/1977/6139/6152/1974/200916/6136/1964/6193/6122/6173/6133/6210/6231/6229/11224/6205/8668/6233/1975/6165/1968/8667/6125/6230/6130 116 Encephalomyocarditis_virus R-HSA-376176 Signaling by ROBO receptors 100/785 218/10654 4.890062498404612e-56 2.03933717526059e-54 1.0752418125146984e-54 5716/6142/6158/6167/7311/6204/6223/25873/6224/6146/6138/51065/6154/6141/6144/26986/6202/6228/23032/23521/6123/6203/116832/6227/9349/387/1630/4736/3921/6188/6189/6232/9775/6206/6194/2935/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/1981/140801/6161/51121/4686/6132/6156/7316/6155/6159/6147/6175/6235/6129/6218/6143/4690/9045/6217/6181/6187/6124/6168/6207/22916/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/5578/6193/6122/6714/6173/6133/6210/6231/6229/11224/6205/7314/5704/6233/6165/6125/6230/6130 100 Encephalomyocarditis_virus R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 49/785 51/10654 8.479866365628559e-54 3.4101176884634844e-52 1.797986703088161e-52 8669/6204/6223/8664/6224/3646/8662/51065/10480/8663/6202/6228/6203/51386/6227/3921/6188/6189/6232/6206/6194/8894/1965/6234/27335/6191/8665/6201/8661/8666/6235/6218/6217/6187/6207/6208/6222/6209/1964/6193/6210/6231/6229/6205/8668/6233/1968/8667/6230 49 Encephalomyocarditis_virus R-HSA-166166 MyD88-independent TLR4 cascade 67/785 99/10654 9.321651383306723e-53 3.49872648586779e-51 1.8447057474333308e-51 7322/8454/6500/23643/1147/64127/330/3665/7311/1432/3725/11035/8945/23118/1326/329/7187/1386/351/23291/841/7099/8517/8772/929/9641/4790/6885/5599/353376/5600/5528/5606/3656/7334/7316/6195/3551/79155/10454/7321/5781/5608/8737/10392/7335/5970/4792/8767/3661/9261/4793/3654/4791/29110/7189/5594/5609/7314/6233/5595/10010/5515/148022/3146/7867/257397 67 Encephalomyocarditis_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 67/785 99/10654 9.321651383306723e-53 3.49872648586779e-51 1.8447057474333308e-51 7322/8454/6500/23643/1147/64127/330/3665/7311/1432/3725/11035/8945/23118/1326/329/7187/1386/351/23291/841/7099/8517/8772/929/9641/4790/6885/5599/353376/5600/5528/5606/3656/7334/7316/6195/3551/79155/10454/7321/5781/5608/8737/10392/7335/5970/4792/8767/3661/9261/4793/3654/4791/29110/7189/5594/5609/7314/6233/5595/10010/5515/148022/3146/7867/257397 67 Encephalomyocarditis_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 64/785 97/10654 2.465144408178223e-49 8.95404065680219e-48 4.721023586460162e-48 54106/8454/6500/23643/51135/1147/64127/3665/7311/1432/3725/8945/23118/1326/246330/1386/351/23291/7099/8517/4615/929/4790/6885/5599/353376/5600/5528/5606/3656/7334/7316/6195/57162/3551/79155/10454/30849/5608/10392/7335/5970/4792/8767/5289/57161/9261/4793/3654/4791/7189/5594/5609/51284/7314/6233/5595/51311/5515/148022/3146/7867/257397/4214 64 Encephalomyocarditis_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 63/785 94/10654 3.1676085897800684e-49 1.1146022725288617e-47 5.876747515249865e-48 7322/8454/6500/1147/64127/330/3665/7311/1432/3725/11035/8945/23118/1326/329/7187/1386/351/23291/841/8517/8772/9641/7098/4790/6885/5599/5600/5528/5606/3656/7334/7316/6195/3551/79155/10454/7321/5608/8737/10392/7335/5970/4792/8767/3661/9261/4793/3654/4791/29110/7189/5594/5609/7314/6233/5595/10010/5515/148022/3146/7867/257397 63 Encephalomyocarditis_virus R-HSA-1632852 Macroautophagy 63/785 95/10654 8.771321128675123e-49 2.992881088147936e-47 1.5779984422879647e-47 2475/51422/7249/55004/8408/58528/7311/1460/5563/23710/64422/7405/84557/5571/10533/10325/5562/53632/84938/11345/10670/115201/8649/55626/153129/84971/26100/9474/7316/65018/6009/83734/5564/9776/11152/23192/5565/8655/30849/389541/64121/79065/5289/57521/7248/55054/9140/81631/55062/140735/11337/22863/440738/8678/6714/8878/7314/10542/6233/28956/60673/9821/64223 63 Encephalomyocarditis_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 62/785 93/10654 3.103033395312115e-48 9.98290172320412e-47 5.263491232950475e-47 54106/8454/6500/23643/51135/1147/64127/3665/7311/1432/3725/8945/23118/1326/246330/1386/351/23291/7099/8517/4615/929/4790/6885/5599/353376/5600/5528/5606/3656/7334/7316/6195/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/57161/9261/4793/3654/4791/7189/5594/5609/51284/7314/6233/5595/51311/5515/148022/3146/7867/257397/4214 62 Encephalomyocarditis_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 62/785 93/10654 3.103033395312115e-48 9.98290172320412e-47 5.263491232950475e-47 54106/8454/6500/23643/51135/1147/64127/3665/7311/1432/3725/8945/23118/1326/246330/1386/351/23291/7099/8517/4615/929/4790/6885/5599/353376/5600/5528/5606/3656/7334/7316/6195/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/57161/9261/4793/3654/4791/7189/5594/5609/51284/7314/6233/5595/51311/5515/148022/3146/7867/257397/4214 62 Encephalomyocarditis_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 62/785 95/10654 2.2825886978056107e-47 6.946472631700318e-46 3.662532078413555e-46 8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/351/23291/10333/7099/8517/4615/929/4790/114609/6885/5599/5600/5528/5606/3656/7334/7316/6195/7097/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/7096/57161/9261/695/59307/4793/3654/4791/7189/5594/5609/7314/6233/5595/5515/3146/7867/257397/4214 62 Encephalomyocarditis_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 62/785 95/10654 2.2825886978056107e-47 6.946472631700318e-46 3.662532078413555e-46 8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/351/23291/10333/7099/8517/4615/929/4790/114609/6885/5599/5600/5528/5606/3656/7334/7316/6195/7097/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/7096/57161/9261/695/59307/4793/3654/4791/7189/5594/5609/7314/6233/5595/5515/3146/7867/257397/4214 62 Encephalomyocarditis_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 61/785 92/10654 3.019863584119189e-47 8.94833262031107e-46 4.718014020618346e-46 54106/8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/351/23291/7099/8517/4615/929/4790/6885/5599/353376/5600/5528/5606/3656/7334/7316/6195/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/57161/9261/4793/3654/4791/7189/5594/5609/51284/7314/6233/5595/51311/5515/148022/3146/7867/257397/4214 61 Encephalomyocarditis_virus R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 84/785 185/10654 1.3609506542562675e-46 3.929308812032198e-45 2.0717305506087315e-45 6142/6158/6167/7311/6204/6223/25873/6224/6146/6138/51065/6154/6141/6144/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/140801/6161/51121/6132/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/6181/6187/6124/6168/6207/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/6233/6165/6125/6230/6130 84 Encephalomyocarditis_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 62/785 98/10654 3.944668385119015e-46 1.0833406345473199e-44 5.71192033172561e-45 8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/351/23291/10333/7099/8517/4615/929/4790/114609/6885/5599/5600/5528/5606/3656/7334/7316/6195/7097/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/7096/57161/9261/695/59307/4793/3654/4791/7189/5594/5609/7314/6233/5595/5515/3146/7867/257397/4214 62 Encephalomyocarditis_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 62/785 98/10654 3.944668385119015e-46 1.0833406345473199e-44 5.71192033172561e-45 8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/351/23291/10333/7099/8517/4615/929/4790/114609/6885/5599/5600/5528/5606/3656/7334/7316/6195/7097/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/7096/57161/9261/695/59307/4793/3654/4791/7189/5594/5609/7314/6233/5595/5515/3146/7867/257397/4214 62 Encephalomyocarditis_virus R-HSA-8868773 rRNA processing in the nucleus and cytosol 84/785 195/10654 2.3083949799992e-44 6.18869701780738e-43 3.262994407818418e-43 6142/6158/6167/7311/6204/6223/25873/6224/6146/6138/51065/6154/6141/6144/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/140801/6161/51121/6132/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/6181/6187/6124/6168/6207/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/6233/6165/6125/6230/6130 84 Encephalomyocarditis_virus R-HSA-9612973 Autophagy 66/785 119/10654 7.843359024869822e-44 2.0538656423263765e-42 1.0829019559428591e-42 2475/51422/7249/55004/8408/58528/7311/1460/5563/23710/64422/7405/84557/5571/10533/3920/10325/5562/53632/84938/11345/10670/115201/8649/55626/153129/3320/84971/26100/9474/7316/65018/6009/83734/5564/9776/11152/23192/5565/8655/30849/389541/64121/79065/5289/57521/7248/55054/9140/81631/55062/140735/11337/22863/440738/8678/6714/8878/7314/10542/6233/28956/60673/9821/3326/64223 66 Encephalomyocarditis_virus R-HSA-1169408 ISG15 antiviral mechanism 52/785 72/10654 1.9507864579790877e-43 4.9922398901919376e-42 2.6321616322971426e-42 8672/23165/7311/9883/9972/348995/9636/23586/317649/79023/81929/57122/23636/5610/11274/5903/25820/23225/1982/7706/8021/9775/10762/55706/7175/129401/9470/23511/1981/7334/9631/7316/1973/53371/55746/3661/8086/4734/9246/1977/5495/1974/6772/8480/51191/23279/4927/9688/7314/6233/5595/79902 52 Encephalomyocarditis_virus R-HSA-72312 rRNA processing 85/785 205/10654 2.7153195833268047e-43 6.794333001835516e-42 3.5823163625644865e-42 6142/6158/6167/7311/6204/6223/25873/6224/6146/6138/51065/6154/6141/6144/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/140801/6161/51121/6132/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/3028/6181/6187/6124/6168/6207/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/6233/6165/6125/6230/6130 85 Encephalomyocarditis_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 53/785 80/10654 4.0682991774357344e-41 9.95848885607095e-40 5.250619533349553e-40 8672/23165/7311/9883/9972/348995/9636/23586/317649/79023/81929/57122/23636/5610/11274/5903/25820/23225/1982/7706/8021/9775/10762/55706/7175/129401/9470/23511/1981/7334/9631/7316/1973/53371/55746/3661/2316/8086/4734/9246/1977/5495/1974/6772/8480/51191/23279/4927/9688/7314/6233/5595/79902 53 Encephalomyocarditis_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 54/785 85/10654 2.0509969255644055e-40 4.713107220786777e-39 2.4849887562155205e-39 8454/6500/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/351/23291/8517/4615/81793/4790/6885/5599/5600/5528/5606/3656/7334/7316/6195/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/57161/9261/4793/3654/4791/7189/5594/5609/7314/6233/5595/5515/3146/7867/257397/4214 54 Encephalomyocarditis_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 54/785 85/10654 2.0509969255644055e-40 4.713107220786777e-39 2.4849887562155205e-39 8454/6500/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/351/23291/8517/4615/81793/4790/6885/5599/5600/5528/5606/3656/7334/7316/6195/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/57161/9261/4793/3654/4791/7189/5594/5609/7314/6233/5595/5515/3146/7867/257397/4214 54 Encephalomyocarditis_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 54/785 85/10654 2.0509969255644055e-40 4.713107220786777e-39 2.4849887562155205e-39 8454/6500/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/351/23291/8517/4615/81793/4790/6885/5599/5600/5528/5606/3656/7334/7316/6195/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/57161/9261/4793/3654/4791/7189/5594/5609/7314/6233/5595/5515/3146/7867/257397/4214 54 Encephalomyocarditis_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 50/785 78/10654 9.030301170360993e-38 2.0336238235652955e-36 1.0722294442281264e-36 7322/1147/7128/3665/7311/84282/9636/1387/54476/23586/79671/7187/351/843/841/7706/8517/8772/84166/9641/7186/4790/80143/8887/9474/64135/7316/1540/3551/3456/7321/8737/5970/4792/83737/3661/9140/4793/9246/4791/29110/7189/57506/51191/7314/6233/79132/10010/3146/4214 50 Encephalomyocarditis_virus R-HSA-73887 Death Receptor Signalling 64/785 141/10654 1.3559617208086637e-35 2.9937507796677555e-34 1.5784569876905808e-34 7124/355/1147/330/7128/7311/7132/4804/57142/23118/329/81858/84894/9099/387/843/841/27005/8517/8772/836/4615/10616/331/396/7186/56957/4790/6885/5599/8717/8887/7316/5584/1540/4803/10018/7531/3551/11108/7185/8743/572/10454/3066/8737/5970/4792/8767/55072/8795/356/65078/4974/3654/7189/7375/835/8878/7314/4099/6233/8797/257397 64 Encephalomyocarditis_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 41/785 55/10654 2.1934589093653786e-35 4.749682176818108e-34 2.504272924862497e-34 4210/1147/64127/330/7128/7311/834/1432/23118/29108/329/837/596/351/841/8517/598/4790/6885/5600/3656/7334/7316/1540/3551/842/10454/5608/10392/7335/5970/8767/83737/3654/4791/7189/835/7314/6233/257397/3326 41 Encephalomyocarditis_virus R-HSA-165159 mTOR signalling 34/785 40/10654 3.952149070038391e-33 8.396452552572128e-32 4.427034906656708e-32 2475/51422/7249/55004/58528/5563/5571/10325/5562/53632/10670/6194/6198/8649/153129/6794/1978/1981/6009/5564/5565/389541/64121/57521/7248/207/1977/7529/208/10542/84335/1975/28956/64223 34 Encephalomyocarditis_virus R-HSA-168638 NOD1/2 Signaling Pathway 32/785 36/10654 1.3929481491989632e-32 2.904554844440801e-31 1.5314283745579247e-31 1147/64127/330/7128/7311/834/1432/23118/329/837/841/8517/6885/5600/3656/7334/7316/1540/3551/842/10454/5608/10392/7335/8767/83737/3654/7189/835/7314/6233/257397 32 Encephalomyocarditis_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 29/785 30/10654 2.4474003445154732e-32 5.010495978044405e-31 2.641787166137277e-31 7124/1147/330/7128/7311/7132/23118/329/81858/9099/27005/8517/10616/331/7186/56957/6885/8717/7316/1540/3551/7185/10454/8737/55072/7375/7314/6233/257397 29 Encephalomyocarditis_virus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 31/785 35/10654 1.7443205266253995e-31 3.507330201750357e-30 1.849242062061514e-30 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10189/10762/55706/7175/129401/23511/4686/9631/7884/10482/53371/55746/22916/8086/1977/8480/23279/4927/9688/79902 31 Encephalomyocarditis_virus R-HSA-450294 MAP kinase activation 41/785 64/10654 3.903472002043684e-31 7.71106925315998e-30 4.0656661295524245e-30 8454/6500/1147/64127/7311/1432/3725/8945/23118/1326/1386/23291/8517/4790/6885/5599/5600/5528/5606/3656/7334/7316/6195/3551/79155/10454/5608/10392/7335/8767/9261/3654/7189/5594/5609/7314/6233/5595/5515/7867/257397 41 Encephalomyocarditis_virus R-HSA-159227 Transport of the SLBP independent Mature mRNA 30/785 34/10654 2.173890175692262e-30 4.22034541005084e-29 2.2251797805634042e-29 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10189/10762/55706/7175/129401/23511/4686/9631/10482/53371/55746/22916/8086/1977/8480/23279/4927/9688/79902 30 Encephalomyocarditis_virus R-HSA-913531 Interferon Signaling 69/785 199/10654 1.7456443157724496e-29 3.3315177958640313e-28 1.7565448601171483e-28 8672/23165/3665/7311/818/9883/9972/10107/348995/9636/23586/317649/79023/81929/57122/23636/5610/11274/5903/6737/25820/23225/1982/7706/8021/9775/10762/55706/7175/3437/3115/129401/9470/23511/1981/7334/7726/9631/7316/1973/3456/53371/3663/5781/10410/55746/3661/2316/8086/10346/4734/9021/9246/1977/5495/5371/1974/6772/8480/9830/51191/23279/4927/9688/7314/6233/5595/5580/79902 69 Encephalomyocarditis_virus R-HSA-1257604 PIP3 activates AKT signaling 80/785 264/10654 1.899560371193819e-29 3.5648416299404e-28 1.879564998865463e-28 2475/5716/5295/7249/55004/51135/8660/58528/1147/2308/7311/1460/5170/27161/3725/2932/10325/2064/1386/10670/1956/5290/192670/2260/4615/29851/8649/3164/331/153129/3667/10000/5528/2100/2309/5291/7316/5728/5468/6009/1822/26523/842/2264/572/5781/3630/192669/389541/3066/64121/7157/57521/8658/10273/207/8975/4734/6045/5987/3654/7189/5371/6714/2099/5594/208/5156/4303/10818/7314/10542/5704/84335/6233/253260/28956/5595/5515/64223 80 Encephalomyocarditis_virus R-HSA-2262752 Cellular responses to stress 110/785 479/10654 1.6649487210789224e-28 3.073331573663716e-27 1.6204160115418677e-27 2475/7322/5716/55004/58528/1030/23165/51343/7311/6119/818/3303/3091/6118/9883/7013/367/9972/1432/348995/3725/2932/538/1387/25913/10325/79023/81929/57122/23636/2034/1019/5903/10670/23225/192670/3576/8021/8649/3313/153129/3309/3320/1780/55662/6117/10762/3490/4790/55706/7175/5599/1021/129401/5600/23511/5606/9631/9448/7316/6195/6009/112399/7531/1029/26523/3456/10935/53371/7321/405/8655/7428/192669/389541/5608/6774/3569/64121/7157/5970/57521/55746/9261/8086/54205/140735/6045/2288/2289/8480/5594/23279/4927/5609/9688/7314/10542/5704/84335/6233/28956/5595/7867/8994/3326/79902/64223/4194/23043 110 Encephalomyocarditis_virus R-HSA-9006925 Intracellular signaling by second messengers 85/785 305/10654 2.3763469866290324e-28 4.315752753135952e-27 2.275483362408785e-27 2475/5716/5295/7249/55004/51135/8660/58528/1147/2308/7311/818/1460/5170/27161/3725/2932/10325/3708/2064/1386/10670/1956/5290/192670/2260/5581/4615/29851/8649/3164/331/153129/3667/10000/5528/2100/2309/5291/7316/5728/5468/6009/1822/26523/842/2264/572/5781/3630/192669/389541/3066/64121/7157/57521/8658/10273/207/8975/4734/6045/5987/3654/7189/5371/5578/6714/2099/5594/208/5156/4303/10818/7314/10542/5704/84335/6233/253260/28956/5595/5515/5580/64223 85 Encephalomyocarditis_virus R-HSA-448424 Interleukin-17 signaling 41/785 72/10654 3.356499694113596e-28 5.9990772310665224e-27 3.163017255605795e-27 8454/6500/1147/64127/7311/1432/3725/8945/23118/1326/1386/23291/8517/4790/6885/5599/5600/5528/5606/3656/7334/7316/6195/3551/79155/10454/5608/10392/7335/8767/9261/3654/7189/5594/5609/7314/6233/5595/5515/7867/257397 41 Encephalomyocarditis_virus R-HSA-5357801 Programmed Cell Death 64/785 181/10654 5.799049179085247e-28 1.0202702149453106e-26 5.3793811463882885e-27 5716/23643/4000/6093/355/1613/330/7311/23604/7161/11035/839/329/840/596/841/1630/7099/999/5588/598/8772/836/331/929/10000/7186/5599/1612/353376/8717/51765/7159/7316/1499/10018/7531/1029/842/8743/572/8655/7082/8737/6774/7157/8795/356/207/8626/54205/140735/7529/5594/208/7314/5704/6233/578/8797/5595/148022/3146/5580 64 Encephalomyocarditis_virus R-HSA-3371556 Cellular response to heat stress 45/785 89/10654 7.519325584499984e-28 1.3025785550995354e-26 6.867853651268003e-27 2475/23165/6119/818/3303/6118/9883/9972/348995/2932/1387/79023/81929/57122/23636/5903/23225/8021/3313/3309/3320/6117/10762/55706/7175/129401/23511/9631/7531/53371/57521/55746/9261/8086/2288/8480/5594/23279/4927/9688/84335/5595/3326/79902/64223 45 Encephalomyocarditis_virus R-HSA-75893 TNF signaling 32/785 43/10654 8.261439120021747e-28 1.4094515832037102e-26 7.431342366335352e-27 7124/1147/330/7128/7311/7132/23118/329/81858/9099/841/27005/8517/8772/10616/331/7186/56957/6885/8717/8887/7316/1540/3551/7185/10454/8737/55072/7375/7314/6233/257397 32 Encephalomyocarditis_virus R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 28/785 33/10654 2.0437202260384244e-27 3.434670111222785e-26 1.8109319834810236e-26 7514/23165/3303/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/5901/55746/8086/8480/23279/4927/9688/79902 28 Encephalomyocarditis_virus R-HSA-8953897 Cellular responses to external stimuli 110/785 493/10654 2.3315431921400006e-27 3.860761226984766e-26 2.0355887931377097e-26 2475/7322/5716/55004/58528/1030/23165/51343/7311/6119/818/3303/3091/6118/9883/7013/367/9972/1432/348995/3725/2932/538/1387/25913/10325/79023/81929/57122/23636/2034/1019/5903/10670/23225/192670/3576/8021/8649/3313/153129/3309/3320/1780/55662/6117/10762/3490/4790/55706/7175/5599/1021/129401/5600/23511/5606/9631/9448/7316/6195/6009/112399/7531/1029/26523/3456/10935/53371/7321/405/8655/7428/192669/389541/5608/6774/3569/64121/7157/5970/57521/55746/9261/8086/54205/140735/6045/2288/2289/8480/5594/23279/4927/5609/9688/7314/10542/5704/84335/6233/28956/5595/7867/8994/3326/79902/64223/4194/23043 110 Encephalomyocarditis_virus R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 27/785 31/10654 4.079289231253596e-27 6.656927064335578e-26 3.509868995312018e-26 7514/23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/5901/55746/8086/8480/23279/4927/9688/79902 27 Encephalomyocarditis_virus R-HSA-71291 Metabolism of amino acids and derivatives 93/785 372/10654 4.791095247017853e-27 7.706818925917289e-26 4.0634251418316824e-26 5716/6142/6158/6167/7311/6204/6223/25873/6224/6146/6138/51065/6154/6141/6144/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/6134/6169/6160/6234/6191/445/8424/6999/6166/6128/6135/6201/6164/140801/6161/51121/6132/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/3028/6181/6187/6124/9380/6168/6207/10165/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/5704/6233/6165/6125/1468/6230/6130 93 Encephalomyocarditis_virus R-HSA-449147 Signaling by Interleukins 105/785 461/10654 6.848356891869458e-27 1.0860915296119732e-25 5.726424443312639e-26 5716/5295/8454/6500/51135/8660/7124/1147/2308/64127/7311/7132/3091/834/6809/1432/3725/7291/8945/23118/1326/596/246330/1386/351/1072/23291/8517/598/1438/5290/836/6778/3576/4615/3313/332/1437/3667/3320/4790/200081/8835/6885/5599/5600/5528/84867/5606/2309/3656/7334/5291/7316/595/6195/4215/57162/6175/3551/79155/10454/5781/5608/10392/27178/6774/3569/7157/7335/5970/4792/8767/57161/356/4170/6850/9261/207/59307/4793/3627/3654/9021/4791/29110/7189/6772/1439/5594/8809/5609/8878/4609/7314/5704/6233/7525/5595/5515/4582/3146/7867/257397/821 105 Encephalomyocarditis_virus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 31/785 42/10654 8.660256308442803e-27 1.3543678615703605e-25 7.140913096435293e-26 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10189/10762/55706/7175/129401/23511/4686/9631/7884/10482/53371/55746/22916/8086/1977/8480/23279/4927/9688/79902 31 Encephalomyocarditis_virus R-HSA-109581 Apoptosis 62/785 178/10654 1.0631646995405757e-26 1.6398951392913537e-25 8.646357469947869e-26 5716/23643/4000/6093/355/1613/7311/23604/7161/839/329/840/596/841/1630/7099/999/5588/598/8772/836/331/929/10000/7186/5599/1612/353376/8717/51765/7159/7316/1499/10018/7531/1029/842/8743/572/8655/7082/8737/6774/7157/8795/356/207/8626/54205/140735/7529/5594/208/7314/5704/6233/578/8797/5595/148022/3146/5580 62 Encephalomyocarditis_virus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 30/785 41/10654 8.993441661376831e-26 1.3684615284743664e-24 7.215222044120246e-25 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10189/10762/55706/7175/129401/23511/4686/9631/10482/53371/55746/22916/8086/1977/8480/23279/4927/9688/79902 30 Encephalomyocarditis_virus R-HSA-5357905 Regulation of TNFR1 signaling 27/785 33/10654 1.245181802478632e-25 1.8694329461212528e-24 9.856597004883488e-25 7124/1147/330/7128/7311/7132/329/81858/9099/841/27005/8517/10616/331/7186/56957/8717/8887/7316/1540/3551/7185/8737/55072/7375/7314/6233 27 Encephalomyocarditis_virus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 23/785 24/10654 1.4706488245547737e-25 2.1788823374324673e-24 1.1488170873253359e-24 64127/7311/1432/23118/8517/6885/5600/5606/3656/7334/7316/10454/5608/10392/7335/8767/9261/3654/7189/7314/6233/7867/257397 23 Encephalomyocarditis_virus R-HSA-3700989 Transcriptional Regulation by TP53 89/785 365/10654 4.643510259317231e-25 6.790379937650912e-24 3.580232106978699e-24 2475/51422/7249/55004/672/55571/355/58528/1025/4850/7311/6119/834/1460/6118/5170/7161/27161/5563/1432/3725/5571/839/1387/4848/10325/5562/53632/1386/10670/23019/9099/843/192670/8649/332/153129/10000/6117/6794/9337/5600/7159/57472/1874/10128/7316/5728/85456/6009/7531/29883/1029/26523/5564/5565/192669/389541/3066/5608/64121/7157/10397/8795/665/57521/8445/7248/207/8626/54205/6790/22974/5371/7529/208/25904/835/7314/10542/6233/253260/28956/8797/246175/4849/5515/64223/4194 89 Encephalomyocarditis_virus R-HSA-165054 Rev-mediated nuclear export of HIV RNA 27/785 34/10654 5.63205298467459e-25 8.027457798409605e-24 4.23248218968217e-24 7514/23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/5901/55746/8086/8480/23279/4927/9688/79902 27 Encephalomyocarditis_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 27/785 34/10654 5.63205298467459e-25 8.027457798409605e-24 4.23248218968217e-24 7322/7128/7311/84282/9636/54476/23586/79671/7187/7706/84166/9641/8887/9474/64135/7316/1540/7321/83737/3661/9140/9246/29110/57506/51191/7314/6233 27 Encephalomyocarditis_virus R-HSA-166208 mTORC1-mediated signalling 22/785 23/10654 1.9639824825407482e-24 2.764305344176103e-23 1.4574817370433974e-23 2475/55004/58528/10325/10670/6194/6198/8649/153129/1978/1981/6009/389541/64121/57521/1977/7529/10542/84335/1975/28956/64223 22 Encephalomyocarditis_virus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 28/785 38/10654 2.8505291093055417e-24 3.9625873791086914e-23 2.0892766960991888e-23 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/7428/55746/8086/5987/5371/8480/23279/4927/9688/79902 28 Encephalomyocarditis_virus R-HSA-180746 Nuclear import of Rev protein 26/785 33/10654 6.263247933357607e-24 8.496888160193573e-23 4.4799896441517955e-23 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/5901/55746/8086/8480/23279/4927/9688/79902 26 Encephalomyocarditis_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 26/785 33/10654 6.263247933357607e-24 8.496888160193573e-23 4.4799896441517955e-23 1147/64127/7311/23118/351/8517/4790/6885/3656/7334/7316/3551/10454/10392/7335/5970/4792/8767/4793/3654/4791/7189/7314/6233/3146/257397 26 Encephalomyocarditis_virus R-HSA-177243 Interactions of Rev with host cellular proteins 27/785 36/10654 8.546958922782564e-24 1.1456994936968056e-22 6.040707810086926e-23 7514/23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/5901/55746/8086/8480/23279/4927/9688/79902 27 Encephalomyocarditis_virus R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 25/785 31/10654 1.6213625869143778e-23 2.098453187201827e-22 1.1064107671139856e-22 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 25 Encephalomyocarditis_virus R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 25/785 31/10654 1.6213625869143778e-23 2.098453187201827e-22 1.1064107671139856e-22 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 25 Encephalomyocarditis_virus R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 25/785 31/10654 1.6213625869143778e-23 2.098453187201827e-22 1.1064107671139856e-22 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 25 Encephalomyocarditis_virus R-HSA-446652 Interleukin-1 family signaling 51/785 140/10654 3.644025424231151e-23 4.662696167823041e-22 2.458409496730107e-22 5716/8454/6500/51135/1147/64127/7311/834/8945/23118/1326/246330/351/23291/8517/4615/4790/6885/5599/84867/3656/7334/7316/4215/57162/3551/79155/10454/5781/5608/10392/27178/6774/7335/5970/4792/8767/57161/59307/4793/3654/4791/29110/7189/8809/8878/7314/5704/6233/3146/257397 51 Encephalomyocarditis_virus R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK 24/785 29/10654 3.923128646100459e-23 4.963418938774289e-22 2.6169657674756463e-22 2475/51422/7249/55004/58528/5563/5571/10325/5562/53632/10670/8649/153129/6794/6009/5564/5565/389541/64121/57521/7248/10542/28956/64223 24 Encephalomyocarditis_virus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 36/785 69/10654 3.9911834317527135e-23 4.993413937948395e-22 2.6327806497175795e-22 23165/6119/3303/6118/9883/9972/348995/2932/79023/81929/57122/23636/5903/23225/8021/3313/3309/6117/10762/55706/7175/129401/23511/9631/7531/53371/55746/9261/8086/8480/5594/23279/4927/9688/5595/79902 36 Encephalomyocarditis_virus R-HSA-429947 Deadenylation of mRNA 22/785 25/10654 1.7036233238485438e-22 2.107999849069737e-21 1.1114442506079569e-21 55571/4850/255967/26986/4848/9924/23019/10605/9775/9337/57472/1981/85456/29883/1973/5073/1977/1974/25904/1975/246175/4849 22 Encephalomyocarditis_virus R-HSA-180910 Vpr-mediated nuclear import of PICs 25/785 33/10654 2.651520593567748e-22 3.2452306395187873e-21 1.711049902485366e-21 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 25 Encephalomyocarditis_virus R-HSA-168276 NS1 Mediated Effects on Host Pathways 27/785 40/10654 8.215254218263568e-22 9.946641128779331e-21 5.244372811658917e-21 23165/9883/9972/348995/9636/79023/81929/57122/23636/5610/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 27 Encephalomyocarditis_virus R-HSA-4085377 SUMOylation of SUMOylation proteins 25/785 34/10654 9.328289284123983e-22 1.1174099716940006e-20 5.891551126815148e-21 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 25 Encephalomyocarditis_virus R-HSA-9020702 Interleukin-1 signaling 42/785 103/10654 1.746794178596173e-21 2.070410784315043e-20 1.0916253924966668e-20 5716/8454/6500/51135/1147/64127/7311/8945/23118/1326/246330/351/23291/8517/4615/4790/6885/3656/7334/7316/4215/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/57161/4793/3654/4791/7189/8878/7314/5704/6233/3146/257397 42 Encephalomyocarditis_virus R-HSA-5260271 Diseases of Immune System 21/785 24/10654 2.0869007102243457e-21 2.4225259790851682e-20 1.2772783511302563e-20 23643/51135/1147/7187/10333/7099/8517/4615/81793/929/7098/4790/114609/7097/3551/5970/4792/7096/695/4791/148022 21 Encephalomyocarditis_virus R-HSA-5602358 Diseases associated with the TLR signaling cascade 21/785 24/10654 2.0869007102243457e-21 2.4225259790851682e-20 1.2772783511302563e-20 23643/51135/1147/7187/10333/7099/8517/4615/81793/929/7098/4790/114609/7097/3551/5970/4792/7096/695/4791/148022 21 Encephalomyocarditis_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 33/785 63/10654 2.2648626181169e-21 2.6022809265302343e-20 1.3720542605992824e-20 1147/147945/3665/7311/11035/1387/197358/81030/6737/8517/6778/4615/7098/4790/5591/7316/1499/51428/3551/2547/8737/5970/4792/3661/4793/4791/29110/3428/7314/7520/6233/23220/148022 33 Encephalomyocarditis_virus R-HSA-5689896 Ovarian tumor domain proteases 26/785 38/10654 2.7799149424654373e-21 3.161802247693013e-20 1.6670622302504058e-20 64127/7128/7311/84282/23586/7187/387/10318/7706/8517/56957/64135/7316/5728/79155/7321/8737/10392/7157/8767/7189/2099/57506/79589/7314/6233 26 Encephalomyocarditis_virus R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 25/785 35/10654 3.0404748190169803e-21 3.42357464621312e-20 1.805081892553239e-20 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 25 Encephalomyocarditis_virus R-HSA-4615885 SUMOylation of DNA replication proteins 28/785 45/10654 4.038916930483972e-21 4.5027925383415364e-20 2.3741002071839086e-20 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/7155/8021/332/10762/55706/7175/129401/23511/9631/53371/55746/8086/6790/8480/23279/4927/9688/79902 28 Encephalomyocarditis_virus R-HSA-168253 Host Interactions with Influenza Factors 27/785 42/10654 5.841777916980896e-21 6.448864641686753e-20 3.400167951679283e-20 23165/9883/9972/348995/9636/79023/81929/57122/23636/5610/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 27 Encephalomyocarditis_virus R-HSA-176033 Interactions of Vpr with host cellular proteins 25/785 36/10654 9.266663119931064e-21 1.0130352109749882e-19 5.341234542300583e-20 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 25 Encephalomyocarditis_virus R-HSA-937041 IKK complex recruitment mediated by RIP1 21/785 25/10654 1.214872719388177e-20 1.3153333481068148e-19 6.935103377883926e-20 7322/23643/1147/330/7311/11035/329/7099/8517/929/353376/7334/7316/3551/7321/8737/7335/7189/7314/6233/148022 21 Encephalomyocarditis_virus R-HSA-5628897 TP53 Regulates Metabolic Genes 37/785 86/10654 4.9298731112933813e-20 5.286702022206044e-19 2.7874169772124988e-19 2475/51422/7249/55004/58528/27161/5563/5571/10325/5562/53632/10670/192670/8649/153129/10000/10128/5728/6009/7531/26523/5564/5565/192669/389541/64121/7157/57521/7248/207/8626/54205/7529/208/10542/28956/64223 37 Encephalomyocarditis_virus R-HSA-2980766 Nuclear Envelope Breakdown 29/785 52/10654 6.00191598709067e-20 6.375620190060465e-19 3.361549768340752e-19 4000/23165/9883/9972/348995/79023/81929/57122/23636/5903/5347/23225/8021/10762/55706/7175/5579/129401/23511/9631/53371/55746/8086/5578/8480/23279/4927/9688/79902 29 Encephalomyocarditis_virus R-HSA-191859 snRNP Assembly 29/785 53/10654 1.2342502588859956e-19 1.2868201773200287e-18 6.784767504987345e-19 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/6606/4686/9631/53371/55746/22916/8086/8480/25929/23279/4927/9688/79902 29 Encephalomyocarditis_virus R-HSA-194441 Metabolism of non-coding RNA 29/785 53/10654 1.2342502588859956e-19 1.2868201773200287e-18 6.784767504987345e-19 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/6606/4686/9631/53371/55746/22916/8086/8480/25929/23279/4927/9688/79902 29 Encephalomyocarditis_virus R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 21/785 27/10654 2.4663285035942555e-19 2.5477852248138826e-18 1.3433213674815647e-18 23643/355/1613/23604/841/1630/7099/8772/836/929/7186/1612/353376/8717/842/8743/8737/8795/356/8797/148022 21 Encephalomyocarditis_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 18/785 20/10654 5.632174545034098e-19 5.662346908668209e-18 2.985475980638376e-18 7322/1147/330/7311/11035/329/8517/7098/7334/7316/3551/7321/8737/7335/7189/7314/6233/148022 18 Encephalomyocarditis_virus R-HSA-5213460 RIPK1-mediated regulated necrosis 18/785 20/10654 5.632174545034098e-19 5.662346908668209e-18 2.985475980638376e-18 355/330/7311/11035/329/841/8772/331/7186/8717/7316/8743/8737/8795/356/7314/6233/8797 18 Encephalomyocarditis_virus R-HSA-5218859 Regulated Necrosis 18/785 20/10654 5.632174545034098e-19 5.662346908668209e-18 2.985475980638376e-18 355/330/7311/11035/329/841/8772/331/7186/8717/7316/8743/8737/8795/356/7314/6233/8797 18 Encephalomyocarditis_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 45/785 134/10654 6.006358441322607e-19 5.985096995512616e-18 3.1556461675882167e-18 7322/5716/5295/8454/6500/1147/7311/5170/3725/8945/23118/10892/3708/4893/23291/8517/5588/5290/4790/3845/6885/5599/7334/5291/7316/3551/10454/7321/7335/5970/4792/6850/695/84433/997/8915/7189/5594/5609/7314/5704/6233/5595/257397/4214 45 Encephalomyocarditis_virus R-HSA-193639 p75NTR signals via NF-kB 16/785 16/10654 6.542973223097293e-19 6.4626209203575016e-18 3.407420958288895e-18 7311/4804/4615/4790/7316/5584/4803/3551/5970/4792/8767/3654/7189/8878/7314/6233 16 Encephalomyocarditis_virus R-HSA-5675482 Regulation of necroptotic cell death 17/785 18/10654 7.933074462894391e-19 7.767514648016594e-18 4.095426999608638e-18 355/330/7311/329/841/8772/331/7186/8717/7316/8743/8737/8795/356/7314/6233/8797 17 Encephalomyocarditis_virus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 19/785 23/10654 1.642399311650933e-18 1.594260021481854e-17 8.405746023331455e-18 64127/7311/23118/8517/6885/5599/3656/7334/7316/10454/10392/7335/8767/3654/7189/5609/7314/6233/257397 19 Encephalomyocarditis_virus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 18/785 21/10654 3.67323864408939e-18 3.5350997549099593e-017 1.8638835764880033e-17 1147/147945/11035/81030/8517/4615/7098/4790/3551/8737/5970/4792/3661/4793/4791/29110/23220/148022 18 Encephalomyocarditis_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 38/785 101/10654 4.034770700231727e-18 3.850128651238072e-17 2.029982760865918e-17 7322/5716/8454/6500/1147/7311/5170/8945/23118/10892/29108/3708/23291/841/8517/4790/6885/7334/7316/3551/10454/7321/9020/7335/5970/4792/6850/84433/997/8915/4791/7189/6714/7314/5704/6233/257397/5580 38 Encephalomyocarditis_virus R-HSA-6807070 PTEN Regulation 45/785 140/10654 4.234006251143815e-18 4.006294990578097e-17 2.1123215618267244e-17 2475/5716/55004/58528/7311/1460/27161/3725/10325/1386/10670/192670/8649/331/153129/10000/7316/5728/5468/6009/1822/26523/192669/389541/3066/64121/7157/57521/8658/10273/207/8975/4734/6045/5987/5371/5594/208/7314/10542/5704/6233/28956/5595/64223 45 Encephalomyocarditis_virus R-HSA-168325 Viral Messenger RNA Synthesis 25/785 43/10654 5.7000467764429815e-18 5.348543891895664e-17 2.820023142029686e-17 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 25 Encephalomyocarditis_virus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 33/785 77/10654 6.102942726155882e-18 5.679267363348366e-17 2.9943973010456e-17 672/23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/6117/10762/55706/7175/129401/23511/8243/9126/9631/1029/53371/55746/8086/6045/5371/8480/8924/23279/4927/9688/79902 33 Encephalomyocarditis_virus R-HSA-4570464 SUMOylation of RNA binding proteins 26/785 47/10654 6.78819175499587e-18 6.265167144365041e-17 3.303313330299975e-17 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/6045/8480/23279/4927/9688/79902 26 Encephalomyocarditis_virus R-HSA-429914 Deadenylation-dependent mRNA decay 28/785 56/10654 1.2788557975392612e-17 1.1707249008367545e-16 6.17265442714714e-17 55571/4850/255967/1656/26986/4848/9924/23019/10605/80153/9775/54464/9337/57472/1981/85456/29883/1973/5073/27257/1977/1974/167227/25904/27258/1975/246175/4849 28 Encephalomyocarditis_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 51/785 182/10654 1.7848730043603544e-17 1.6207798410562573e-016 8.545571939382342e-17 672/23165/9883/367/9972/348995/1387/79023/10499/81929/57122/23636/5903/23225/7155/8517/8021/332/9641/6117/10762/55706/7175/129401/23511/8243/9126/9631/7022/5468/1029/53371/7428/3066/7157/5970/4792/55746/8086/6045/6790/5987/4791/5371/8480/8924/2099/23279/4927/9688/79902 51 Encephalomyocarditis_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 27/785 53/10654 2.6321227148622552e-17 2.3710161415479195e-16 1.250119756785105e-16 7161/840/596/841/598/836/331/10000/5599/7159/10018/7531/1029/842/572/8655/6774/7157/207/8626/54205/140735/7529/5594/208/578/5595 27 Encephalomyocarditis_virus R-HSA-5621481 C-type lectin receptors (CLRs) 44/785 142/10654 4.81344446851432e-17 4.3015384694818445e-16 2.2679888723826873e-16 7322/5716/8454/6500/1147/7311/3384/5170/8945/23118/10892/29108/1387/3708/4893/23291/841/8517/4790/3845/6885/7334/7316/3551/10454/7321/9020/7335/5970/4792/6850/5894/84433/997/8915/4791/7189/6714/7314/5704/6233/4582/257397/5580 44 Encephalomyocarditis_virus R-HSA-5663202 Diseases of signal transduction 77/785 377/10654 6.396680939155119e-17 5.671387982274539e-16 2.990242892402393e-16 2475/5716/5295/7249/8454/6500/4000/5037/8660/1147/2308/7311/818/51009/5170/2932/10533/1387/2064/57534/4893/1956/5290/2260/29851/4140/3164/3667/10000/3320/3845/142678/5528/2100/2309/4686/5291/7316/1499/5728/2648/10018/369/55869/842/1445/2264/572/8315/5781/3066/4296/6774/8658/22916/5894/207/4087/11140/6772/6714/2099/7529/5594/208/5156/4303/4609/10818/7314/5704/84335/6233/253260/5595/5515/64223 77 Encephalomyocarditis_virus R-HSA-2990846 SUMOylation 51/785 188/10654 8.030016519766286e-17 7.063905157231904e-16 3.7244484516021263e-16 672/23165/9883/367/9972/348995/1387/79023/10499/81929/57122/23636/5903/23225/7155/8517/8021/332/9641/6117/10762/55706/7175/129401/23511/8243/9126/9631/7022/5468/1029/53371/7428/3066/7157/5970/4792/55746/8086/6045/6790/5987/4791/5371/8480/8924/2099/23279/4927/9688/79902 51 Encephalomyocarditis_virus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 16/785 18/10654 8.69501388194694e-17 7.589601264397096e-16 4.0016220558287017e-16 23643/3665/7311/7187/7099/929/9641/353376/7316/5781/3661/29110/7314/6233/10010/148022 16 Encephalomyocarditis_virus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 15/785 16/10654 1.3483113418204493e-16 1.1678450545306352e-15 6.157470419325776e-16 23643/7311/23118/7099/929/6885/353376/3656/7316/10454/7189/7314/6233/148022/257397 15 Encephalomyocarditis_virus R-HSA-72202 Transport of Mature Transcript to Cytoplasm 33/785 84/10654 1.4497915114018905e-16 1.2461566731591824e-15 6.570368922705234e-16 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/9775/10189/10762/55706/7175/129401/23511/4686/9631/7884/10482/53371/55746/22916/8086/1977/6428/8480/23279/4927/9688/79902 33 Encephalomyocarditis_virus R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 31/785 75/10654 2.186053923109609e-16 1.864770240470773e-15 9.832012859918816e-16 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/9775/10189/10762/55706/7175/129401/23511/4686/9631/10482/53371/55746/22916/8086/6428/8480/23279/4927/9688/79902 31 Encephalomyocarditis_virus R-HSA-933542 TRAF6 mediated NF-kB activation 18/785 24/10654 3.0066114717804474e-16 2.5454470054321685e-15 1.3420885398370974e-15 1147/84282/23586/351/7706/8517/7186/4790/64135/3551/5970/4792/4793/4791/7189/57506/3146/4214 18 Encephalomyocarditis_virus R-HSA-70171 Glycolysis 30/785 71/10654 3.2161565181700066e-16 2.7025315219846473e-15 1.424911450312556e-15 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/2597/10762/55706/7175/129401/23511/5528/9631/53371/5230/55746/8086/3098/8480/23279/4927/9688/5515/79902 30 Encephalomyocarditis_virus R-HSA-202424 Downstream TCR signaling 35/785 98/10654 5.785794528536276e-16 4.8257812141717385e-15 2.5443961903270645e-15 7322/5716/5295/8454/6500/1147/7311/5170/8945/23118/10892/23291/8517/5588/5290/4790/6885/3115/7334/5291/7316/5728/3551/7321/7335/5970/4792/8767/84433/997/8915/7189/7314/5704/6233 35 Encephalomyocarditis_virus R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 15/785 17/10654 1.068317475222544e-15 8.780477935040763e-15 4.629512531890241e-15 23643/355/841/7099/8772/929/7186/353376/8717/8743/8737/8795/356/8797/148022 15 Encephalomyocarditis_virus R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 15/785 17/10654 1.068317475222544e-15 8.780477935040763e-15 4.629512531890241e-15 23643/7311/23118/7099/929/6885/353376/3656/7316/10454/7189/7314/6233/148022/257397 15 Encephalomyocarditis_virus R-HSA-209543 p75NTR recruits signalling complexes 13/785 13/10654 1.7196403203304253e-15 1.3738953207858718e-14 7.243871748370868e-15 7311/4804/4615/7316/5584/4803/3551/8767/3654/7189/8878/7314/6233 13 Encephalomyocarditis_virus R-HSA-209560 NF-kB is activated and signals survival 13/785 13/10654 1.7196403203304253e-15 1.3738953207858718e-14 7.243871748370868e-15 7311/4804/4790/7316/4803/3551/5970/4792/3654/7189/8878/7314/6233 13 Encephalomyocarditis_virus R-HSA-5357786 TNFR1-induced proapoptotic signaling 13/785 13/10654 1.7196403203304253e-15 1.3738953207858718e-14 7.243871748370868e-15 7124/7128/7132/9099/841/27005/8772/7186/56957/8717/1540/8737/7375 13 Encephalomyocarditis_virus R-HSA-937039 IRAK1 recruits IKK complex 14/785 15/10654 1.7448226542840112e-15 1.3738953207858718e-14 7.243871748370868e-15 1147/7311/246330/8517/7334/7316/57162/3551/7335/57161/3654/7189/7314/6233 14 Encephalomyocarditis_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 14/785 15/10654 1.7448226542840112e-15 1.3738953207858718e-14 7.243871748370868e-15 54106/51135/3665/7311/4615/7334/7316/7335/3654/7189/51284/7314/6233/51311 14 Encephalomyocarditis_virus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 14/785 15/10654 1.7448226542840112e-15 1.3738953207858718e-14 7.243871748370868e-15 1147/7311/246330/8517/7334/7316/57162/3551/7335/57161/3654/7189/7314/6233 14 Encephalomyocarditis_virus R-HSA-6784531 tRNA processing in the nucleus 26/785 57/10654 3.2424146531058855e-15 2.5353881245814078e-14 1.3367849885611986e-14 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/5901/55746/8086/8480/23279/4927/9688/79902 26 Encephalomyocarditis_virus R-HSA-2871837 FCERI mediated NF-kB activation 31/785 82/10654 4.358628261014695e-15 3.384700290967274e-14 1.7845853642194472e-14 7322/5716/8454/6500/1147/7311/5170/8945/23118/10892/23291/8517/5588/4790/6885/7334/7316/3551/10454/7321/7335/5970/4792/84433/997/8915/7189/7314/5704/6233/257397 31 Encephalomyocarditis_virus R-HSA-2219528 PI3K/AKT Signaling in Cancer 34/785 101/10654 1.1687907325155908e-14 9.01409838912709e-14 4.7526890637259786e-14 2475/5295/7249/8660/1147/2308/5170/2932/2064/1956/5290/2260/29851/3164/3667/10000/2100/2309/5291/5728/842/2264/572/5781/207/6714/2099/208/5156/4303/10818/84335/253260/64223 34 Encephalomyocarditis_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 14/785 16/10654 1.3014763294997884e-14 9.969131612358923e-14 5.2562309333181575e-14 8454/6500/1147/7311/8945/1326/23291/8517/4790/7316/3551/79155/7314/6233 14 Encephalomyocarditis_virus R-HSA-202403 TCR signaling 37/785 119/10654 1.3837329988298337e-14 1.0527590247854005e-13 5.5506786012804146e-14 7322/5716/5295/8454/6500/1147/7311/5170/8945/23118/10892/23291/8517/5588/5290/4790/6885/3115/7334/5291/7316/5728/3551/4690/1445/7321/7335/5970/4792/8767/84433/997/8915/7189/7314/5704/6233 37 Encephalomyocarditis_virus R-HSA-70326 Glucose metabolism 32/785 91/10654 1.7396853911315707e-14 1.3146884230967442e-13 6.931703006698736e-14 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/2597/10762/55706/7175/129401/23511/5528/9631/53371/5230/55746/10165/8086/3098/8480/23279/4927/9688/5515/1468/79902 32 Encephalomyocarditis_virus R-HSA-918233 TRAF3-dependent IRF activation pathway 13/785 14/10654 2.2453095275450535e-14 1.6854790186771536e-13 8.886698761652001e-14 3665/84282/1387/23586/7187/7706/9641/80143/64135/3456/3661/29110/57506 13 Encephalomyocarditis_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 12/785 12/10654 2.3674530774846545e-14 1.7537843192419217e-13 9.246838889898513e-14 3665/7311/7187/9641/7098/7316/3661/29110/7314/6233/10010/148022 12 Encephalomyocarditis_virus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12/785 12/10654 2.3674530774846545e-14 1.7537843192419217e-13 9.246838889898513e-14 1147/84282/23586/843/841/7706/8517/8772/64135/3551/8737/57506 12 Encephalomyocarditis_virus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 17/785 25/10654 2.9083324044803975e-14 2.1403805800293643e-13 1.1285170114392461e-13 2475/7249/1147/2308/5170/2932/3164/10000/2309/842/572/207/208/4303/84335/253260/64223 17 Encephalomyocarditis_virus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 14/785 17/10654 6.876484378728218e-14 5.027871045745437e-13 2.650948181546627e-13 1147/11035/81030/8517/4615/7098/4790/3551/8737/5970/4792/4793/4791/148022 14 Encephalomyocarditis_virus R-HSA-1227986 Signaling by ERBB2 23/785 50/10654 1.0419391189645749e-13 7.569183535187815e-13 3.990856795219153e-13 5295/7311/2064/4893/387/1956/5290/5581/10000/3320/3845/7316/10273/207/11140/5578/6714/10193/208/7314/6233/7525/5580 23 Encephalomyocarditis_virus R-HSA-4551638 SUMOylation of chromatin organization proteins 27/785 71/10654 2.204226450061053e-13 1.5909993479286832e-12 8.388554101446924e-13 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/3066/55746/8086/6045/8480/23279/4927/9688/79902 27 Encephalomyocarditis_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 81/785 473/10654 3.158294912236702e-13 2.265121064444921e-12 1.1942865105608446e-12 2475/5295/54106/8569/3315/8660/23191/6093/7311/3178/5170/1432/23118/3708/2064/1213/4670/5590/4893/387/1956/5290/4914/6778/2260/5581/3667/10000/3320/3845/5579/5600/5528/4686/5291/7316/1499/6195/4803/8471/4690/1445/2264/5781/3630/30849/6774/8877/11059/5289/83737/22916/10273/9261/207/4734/5725/11140/10413/10458/5578/6772/6714/2099/7529/5594/10193/208/5156/10818/7314/6233/253260/7525/5595/5515/7867/3910/5580/64223/5607 81 Encephalomyocarditis_virus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 11/785 11/10654 3.2554009177867143e-13 2.319988249004962e-12 1.2232152682423098e-12 7311/23118/7098/6885/7316/10454/7189/7314/6233/148022/257397 11 Encephalomyocarditis_virus R-HSA-5688426 Deubiquitination 60/785 297/10654 3.466003063472766e-13 2.454540534258072e-12 1.2941580455469316e-12 5716/672/64127/330/7128/7311/3091/84282/367/9097/23586/329/23032/11274/7187/4287/9099/387/27005/10318/7706/8517/7186/56957/6885/51651/64135/7316/5728/1540/2648/79155/10454/7321/8737/10392/7157/4792/8767/8658/8975/4087/63891/5886/7189/7375/8678/9817/2099/57506/9100/57599/4303/79589/4609/7314/10445/5704/6233/4194 60 Encephalomyocarditis_virus R-HSA-193704 p75 NTR receptor-mediated signalling 31/785 97/10654 8.628402179119916e-13 6.072238033555641e-12 3.2015913348839693e-12 7311/4804/57142/84894/387/836/4615/396/4790/5599/7316/5584/4803/10018/7531/3551/11108/572/3066/5970/4792/8767/65078/4974/3654/7189/835/8878/7314/4099/6233 31 Encephalomyocarditis_virus R-HSA-162909 Host Interactions of HIV factors 36/785 129/10654 1.2124244617953533e-12 8.479440645848248e-12 4.470790431203527e-12 5716/6500/7514/1025/23165/7311/9883/9972/348995/8945/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/7316/53371/5901/55746/8086/8480/23279/4927/9688/7314/5704/6233/79902 36 Encephalomyocarditis_virus R-HSA-4420097 VEGFA-VEGFR2 Pathway 31/785 99/10654 1.5933214877387242e-12 1.1074567871566688e-11 5.839072898535676e-12 2475/5295/3315/23191/6093/5170/1432/3708/5590/4893/387/5290/10000/3320/3845/5579/5600/5291/1499/4690/8877/9261/207/10458/5578/6714/208/253260/7867/5580/64223 31 Encephalomyocarditis_virus R-HSA-162587 HIV Life Cycle 39/785 152/10654 2.5627728120283394e-12 1.770357169536141e-11 9.334219347652461e-12 7514/1025/23165/7311/23327/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/4686/9631/7316/2547/53371/5901/55746/22916/8086/51534/8480/23279/4927/9688/7314/7520/6233/8731/79902 39 Encephalomyocarditis_virus R-HSA-162599 Late Phase of HIV Life Cycle 37/785 139/10654 2.837309937287616e-12 1.9480554813328388e-11 1.0271134817908957e-11 7514/1025/23165/7311/23327/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/4686/9631/7316/53371/5901/55746/22916/8086/51534/8480/23279/4927/9688/7314/6233/8731/79902 37 Encephalomyocarditis_virus R-HSA-5633007 Regulation of TP53 Activity 40/785 160/10654 3.2916730085599776e-12 2.2463174591748695e-11 1.1843722978167959e-11 2475/51422/672/7311/6119/1460/6118/5170/7161/5563/1432/5571/5562/53632/9099/10000/6117/6794/5600/7159/7316/1029/5564/5565/3066/5608/7157/8445/207/8626/6790/22974/5371/208/7314/6233/253260/5515/64223/4194 40 Encephalomyocarditis_virus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 10/785 10/10654 4.471030628247976e-12 3.032759329763386e-11 1.5990242703436007e-11 7311/23118/6885/3656/7316/10454/7189/7314/6233/257397 10 Encephalomyocarditis_virus R-HSA-194138 Signaling by VEGF 31/785 107/10654 1.5574040122805173e-11 1.0500819867232709e-10 5.536563901205243e-11 2475/5295/3315/23191/6093/5170/1432/3708/5590/4893/387/5290/10000/3320/3845/5579/5600/5291/1499/4690/8877/9261/207/10458/5578/6714/208/253260/7867/5580/64223 31 Encephalomyocarditis_virus R-HSA-8943724 Regulation of PTEN gene transcription 23/785 61/10654 1.657077645852295e-11 1.1106365650176693e-10 5.855838297372773e-11 2475/55004/58528/3725/10325/1386/10670/8649/153129/5468/6009/1822/389541/3066/64121/7157/57521/6045/5594/10542/28956/5595/64223 23 Encephalomyocarditis_virus R-HSA-1169091 Activation of NF-kappaB in B cells 24/785 67/10654 2.1533057601632573e-11 1.4346877431620282e-10 7.564400178960306e-11 5716/8454/6500/1147/7311/8945/10892/23291/8517/4794/4790/6885/5579/5966/7316/3551/5970/4792/84433/4793/8915/7314/5704/6233 24 Encephalomyocarditis_virus R-HSA-1834941 STING mediated induction of host immune responses 12/785 16/10654 3.2647651007829316e-11 2.162426766753871e-10 1.1401408773012838e-10 147945/197358/6737/6778/5591/51428/2547/3661/29110/3428/7520/23220 12 Encephalomyocarditis_virus R-HSA-3371378 Regulation by c-FLIP 10/785 11/10654 4.592593599294101e-11 2.9719887314972174e-10 1.5669829340604195e-10 355/841/8772/7186/8717/8743/8737/8795/356/8797 10 Encephalomyocarditis_virus R-HSA-5218900 CASP8 activity is inhibited 10/785 11/10654 4.592593599294101e-11 2.9719887314972174e-10 1.5669829340604195e-10 355/841/8772/7186/8717/8743/8737/8795/356/8797 10 Encephalomyocarditis_virus R-HSA-5603041 IRAK4 deficiency (TLR2/4) 10/785 11/10654 4.592593599294101e-11 2.9719887314972174e-10 1.5669829340604195e-10 23643/51135/10333/7099/4615/929/114609/7097/7096/695 10 Encephalomyocarditis_virus R-HSA-69416 Dimerization of procaspase-8 10/785 11/10654 4.592593599294101e-11 2.9719887314972174e-10 1.5669829340604195e-10 355/841/8772/7186/8717/8743/8737/8795/356/8797 10 Encephalomyocarditis_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 31/785 112/10654 5.710274264234443e-11 3.6741536123017046e-10 1.937199810543294e-10 5716/5295/8454/6500/1147/7311/8945/10892/3708/4893/23291/8517/4794/4790/3845/6885/5579/5966/7316/3551/4690/5970/4792/6850/695/84433/4793/8915/7314/5704/6233 31 Encephalomyocarditis_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 26/785 83/10654 1.0066063173655304e-10 6.439992689509018e-10 3.3954902092952106e-10 5716/8454/6500/1147/7311/8945/10892/4893/23291/8517/4794/4790/3845/6885/5579/5966/7316/3551/5970/4792/84433/4793/8915/7314/5704/6233 26 Encephalomyocarditis_virus R-HSA-187037 Signaling by NTRK1 (TRKA) 25/785 80/10654 2.4484006963090473e-10 1.557570160476829e-9 8.212298499662817e-10 5295/8660/1432/1213/4893/387/5290/4914/3667/3845/5600/5528/5291/6195/4803/6774/9261/6714/7529/5594/10818/5595/5515/7867/5607 25 Encephalomyocarditis_virus R-HSA-933541 TRAF6 mediated IRF7 activation 15/785 29/10654 2.6254308812387193e-10 1.6608062765588752e-9 8.756611573143926e-10 3665/84282/1387/23586/7706/9641/7186/80143/64135/3456/3661/29110/7189/57506/10010 15 Encephalomyocarditis_virus R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 11/785 15/10654 3.3726213872061593e-10 2.1215484256950475e-9 1.1185877461830483e-9 147945/7311/81030/6737/7316/51428/3661/29110/7314/6233/23220 11 Encephalomyocarditis_virus R-HSA-114452 Activation of BH3-only proteins 15/785 30/10654 4.895643066152974e-10 3.0624967180490267e-9 1.6147033270820335e-9 7161/596/10000/5599/7159/10018/7531/572/8655/7157/207/8626/140735/7529/208 15 Encephalomyocarditis_virus R-HSA-193697 p75NTR regulates axonogenesis 9/785 10/10654 5.730870263779779e-10 3.526207604926793e-9 1.8591951847982719e-9 4804/57142/84894/387/396/4803/65078/4974/4099 9 Encephalomyocarditis_virus R-HSA-2562578 TRIF-mediated programmed cell death 9/785 10/10654 5.730870263779779e-10 3.526207604926793e-9 1.8591951847982719e-9 23643/11035/841/7099/8772/929/353376/8737/148022 9 Encephalomyocarditis_virus R-HSA-5602498 MyD88 deficiency (TLR2/4) 9/785 10/10654 5.730870263779779e-10 3.526207604926793e-9 1.8591951847982719e-9 23643/10333/7099/4615/929/114609/7097/7096/695 9 Encephalomyocarditis_virus R-HSA-5675221 Negative regulation of MAPK pathway 17/785 40/10654 8.292074453082909e-10 5.074389040310519e-9 2.6754748235347603e-9 5037/7311/4893/4140/1843/3845/5528/7316/369/8315/5894/7529/5594/7314/6233/5595/5515 17 Encephalomyocarditis_virus R-HSA-199418 Negative regulation of the PI3K/AKT network 29/785 110/10654 8.457219987206541e-10 5.147475516537603e-9 2.7140097142443754e-9 5295/51135/8660/2064/1956/5290/2260/4615/29851/3667/10000/5528/2100/5291/5728/2264/5781/3630/207/3654/7189/6714/2099/5594/208/5156/10818/5595/5515 29 Encephalomyocarditis_virus R-HSA-3270619 IRF3-mediated induction of type I IFN 10/785 13/10654 1.0413424567250975e-9 6.304040893937956e-9 3.323809539292332e-9 147945/197358/5591/51428/2547/3661/29110/3428/7520/23220 10 Encephalomyocarditis_virus R-HSA-6804757 Regulation of TP53 Degradation 16/785 36/10654 1.1711652650422496e-9 7.0520432536768614e-9 3.718194255467655e-9 2475/7311/5170/9099/10000/7316/1029/7157/207/208/7314/6233/253260/5515/64223/4194 16 Encephalomyocarditis_virus R-HSA-5619102 SLC transporter disorders 27/785 99/10654 1.4311333572633599e-9 8.571575320630549e-9 4.5193684966211366e-9 23165/9883/9972/348995/79023/81929/57122/23636/10999/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/3098/8480/23279/4927/9688/79902 27 Encephalomyocarditis_virus R-HSA-5578749 Transcriptional regulation by small RNAs 28/785 106/10654 1.5770139992689853e-9 9.395332080300938e-9 4.953694767962728e-9 23165/9883/27161/9972/348995/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/26523/53371/5901/55746/8086/8480/23279/4927/9688/79902 28 Encephalomyocarditis_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 16/785 37/10654 1.9236094111622953e-9 1.1399916826151286e-8 6.0106133401414654e-9 2475/7311/5170/9099/10000/7316/1029/7157/207/208/7314/6233/253260/5515/64223/4194 16 Encephalomyocarditis_virus R-HSA-211000 Gene Silencing by RNA 32/785 136/10654 2.5658592674477474e-9 1.512647924160295e-8 7.975445725216475e-9 23165/9883/27161/9972/348995/79023/81929/57122/23636/5903/23225/192670/8021/3320/10762/55706/7175/129401/23511/9631/26523/53371/192669/5901/55746/23405/8086/8480/23279/4927/9688/79902 32 Encephalomyocarditis_virus R-HSA-2559585 Oncogene Induced Senescence 15/785 33/10654 2.6532346680293976e-9 1.5560115813547404e-8 8.20408088140669e-9 1030/7311/1019/192670/1021/7316/1029/26523/192669/7157/5594/7314/6233/5595/4194 15 Encephalomyocarditis_virus R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 9/785 11/10654 2.945311933110653e-9 1.718352972374402e-8 9.060026889961321e-9 7311/23118/6885/7316/10454/7189/7314/6233/257397 9 Encephalomyocarditis_virus R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 12/785 21/10654 3.72947150476306e-9 2.1646313991562915e-8 1.1413032711266231e-8 55571/4850/4848/23019/9337/57472/85456/29883/7157/25904/246175/4849 12 Encephalomyocarditis_virus R-HSA-74751 Insulin receptor signalling cascade 19/785 54/10654 3.802722218495802e-9 2.19582831693655e-8 1.1577518657120821e-8 5295/54106/8660/5170/4893/5290/2260/3667/3845/5291/2264/5781/3630/30849/5289/5594/208/10818/5595 19 Encephalomyocarditis_virus R-HSA-5683057 MAPK family signaling cascades 51/785 294/10654 6.111605411324585e-9 3.5110549454854503e-8 1.8512059355462223e-8 5716/3315/5037/8660/7514/2308/7311/818/27161/3725/2064/4893/1956/1438/192670/2260/4140/8649/1437/3667/1843/8452/3845/5528/2309/7316/26523/369/1445/2264/8315/5781/192669/4296/8202/3569/5597/5894/1439/6714/7529/5594/5156/4609/10818/7314/5704/6233/28956/5595/5515 51 Encephalomyocarditis_virus R-HSA-2559583 Cellular Senescence 39/785 195/10654 7.055098449707191e-9 4.019849574505735e-8 2.1194682247557585e-8 1030/51343/7311/7013/1432/3725/25913/1019/192670/3576/3490/4790/5599/1021/5600/5606/9448/7316/6195/1029/26523/3456/7321/192669/5608/6774/3569/7157/5970/9261/6045/5594/5609/7314/6233/5595/7867/4194/23043 39 Encephalomyocarditis_virus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 45/785 244/10654 7.068652004903513e-9 4.019849574505735e-8 2.1194682247557585e-8 23165/3178/9883/9972/348995/79023/81929/57122/23636/4670/5903/23225/8021/9775/3192/10189/10762/55706/7175/129401/23511/4686/9631/7884/10482/53371/9343/55746/22916/8086/56339/56259/5725/9879/1977/3191/6428/8480/57721/23279/4927/9688/27258/1994/79902 45 Encephalomyocarditis_virus R-HSA-5689880 Ub-specific processing proteases 42/785 220/10654 7.908590177823779e-9 4.474910824235967e-8 2.3593995558278828e-8 5716/330/7311/3091/367/9097/23586/329/23032/11274/9099/27005/8517/7186/6885/51651/64135/7316/5728/1540/2648/10454/8737/7157/4792/8658/8975/4087/63891/7189/7375/8678/9817/9100/57599/4303/79589/4609/7314/5704/6233/4194 42 Encephalomyocarditis_virus R-HSA-68875 Mitotic Prophase 32/785 142/10654 7.993048774242416e-9 4.5000864598984805e-8 2.3726734256172227e-8 4000/23165/9883/9972/348995/79023/81929/57122/23636/5903/5347/23225/8021/10762/55706/7175/5579/129401/23511/9631/53371/55746/8086/5578/8480/5594/23279/4927/9688/5595/5515/79902 32 Encephalomyocarditis_virus R-HSA-72306 tRNA processing 27/785 107/10654 9.110198289093134e-9 5.103524016676054e-8 2.6908362582081843e-8 23165/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/3028/5901/55746/8086/8480/23279/4927/9688/79902 27 Encephalomyocarditis_virus R-HSA-166520 Signaling by NTRKs 26/785 101/10654 1.0925095896787951e-8 6.089929692961997e-8 3.210919273469726e-8 5295/8660/1432/1213/4893/387/5290/4914/3667/3845/5600/5528/5291/6195/4803/5781/6774/9261/6714/7529/5594/10818/5595/5515/7867/5607 26 Encephalomyocarditis_virus R-HSA-5654743 Signaling by FGFR4 16/785 41/10654 1.1631584022863013e-8 6.451804733863917e-8 3.401718117134944e-8 5295/8569/7311/4893/5290/3845/7316/2264/5781/6714/5594/10818/7314/6233/5595/5515 16 Encephalomyocarditis_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 11/785 19/10654 1.4180651865265485e-8 7.788982439165335e-8 4.1067459060383745e-8 5295/7311/4893/1956/5290/3320/3845/7316/11140/7314/6233 11 Encephalomyocarditis_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 11/785 19/10654 1.4180651865265485e-8 7.788982439165335e-8 4.1067459060383745e-8 5295/7311/4893/1956/5290/3320/3845/7316/11140/7314/6233 11 Encephalomyocarditis_virus R-HSA-162906 HIV Infection 43/785 233/10654 1.504939105549904e-8 8.22602637305433e-8 4.3371775959639556e-8 5716/6500/7514/1025/23165/7311/23327/9883/9972/348995/8945/79023/81929/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/4686/9631/7316/2547/53371/5901/55746/22916/8086/51534/8480/23279/4927/9688/7314/5704/7520/6233/8731/79902 43 Encephalomyocarditis_virus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 26/785 103/10654 1.701539430349549e-8 9.255716901321701e-8 4.880082576746227e-8 5295/51135/8660/2064/1956/5290/2260/4615/29851/3667/5528/2100/5291/2264/5781/3630/207/3654/7189/6714/2099/5594/5156/10818/5595/5515 26 Encephalomyocarditis_virus R-HSA-9009391 Extra-nuclear estrogen signaling 22/785 77/10654 1.880504294438147e-8 1.0180037670852661e-7 5.367431285744509e-8 5295/3315/7514/5170/596/5590/4893/1956/5290/10000/3320/3845/2100/2309/595/8877/207/6714/2099/5594/208/5595 22 Encephalomyocarditis_virus R-HSA-1295596 Spry regulation of FGF signaling 10/785 16/10654 2.3752800936274168e-8 1.2796963566624266e-7 6.747207115617543e-8 8569/7311/7316/5781/6714/5594/7314/6233/5595/5515 10 Encephalomyocarditis_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 24/785 92/10654 3.031915425075991e-8 1.6256841755407457e-7 8.571430073899043e-8 51422/672/7311/6119/1460/6118/5563/1432/5571/5562/53632/6117/6794/5600/7316/5564/5565/7157/8445/6790/22974/7314/6233/4194 24 Encephalomyocarditis_virus R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 8/785 10/10654 3.306982049775841e-8 1.764768619927771e-7 9.304753684577572e-8 51422/5563/1432/5571/53632/5600/5564/5565 8 Encephalomyocarditis_virus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 9/785 13/10654 3.3437112833782486e-8 1.7759523137188244e-7 9.363719780662027e-8 7311/2064/10000/7316/207/10193/208/7314/6233 9 Encephalomyocarditis_virus R-HSA-5205647 Mitophagy 13/785 29/10654 3.833280144861397e-8 2.0169502070625853e-7 1.0634382694057195e-7 8408/7311/1460/84557/9474/7316/65018/9140/81631/6714/8878/7314/6233 13 Encephalomyocarditis_virus R-HSA-8863795 Downregulation of ERBB2 signaling 13/785 29/10654 3.833280144861397e-8 2.0169502070625853e-7 1.0634382694057195e-7 7311/2064/1956/10000/3320/7316/10273/207/11140/10193/208/7314/6233 13 Encephalomyocarditis_virus R-HSA-9607240 FLT3 Signaling 46/785 267/10654 4.2817511149522504e-8 2.2424426769470855e-7 1.1823293164421394e-7 5716/5295/54106/5037/8660/7311/818/5170/2064/4893/1956/1438/5290/2260/4140/8649/1437/3667/1843/8452/3845/5528/5291/7316/369/1445/2264/8315/5781/30849/4296/5289/5894/1439/6714/7529/5594/208/5156/10818/7314/5704/6233/28956/5595/5515 46 Encephalomyocarditis_virus R-HSA-5619115 Disorders of transmembrane transporters 35/785 176/10654 4.8834763925543724e-8 2.5457381564889924e-7 1.3422420494155295e-7 5716/23165/7311/9883/51009/9972/348995/79023/81929/57122/23636/10999/5903/23225/8021/10762/55706/7175/129401/23511/9631/7316/53371/79139/55746/8086/3098/8480/23279/4927/9688/7314/5704/6233/79902 35 Encephalomyocarditis_virus R-HSA-8934593 Regulation of RUNX1 Expression and Activity 10/785 17/10654 5.3878999635974345e-8 2.7957490133689915e-7 1.4740604314668704e-7 27161/894/192670/1021/595/26523/5781/192669/5371/6714 10 Encephalomyocarditis_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 23/785 88/10654 5.6562541491067666e-8 2.9215331063734954e-7 1.540380173875527e-7 5716/3315/7514/7311/3303/1432/26986/8021/54464/5600/1981/7316/5073/9261/207/167227/5578/7529/7314/5704/6233/1994/5580 23 Encephalomyocarditis_virus R-HSA-5654741 Signaling by FGFR3 15/785 40/10654 6.30749077333485e-8 3.243029502637005e-7 1.7098893516754894e-7 5295/8569/7311/4893/5290/3845/7316/5781/6714/5594/10818/7314/6233/5595/5515 15 Encephalomyocarditis_virus R-HSA-983169 Class I MHC mediated antigen processing & presentation 57/785 371/10654 6.988303846140292e-8 3.576740968524531e-7 1.8858389326426433e-7 7322/5716/8454/6500/23643/57154/1147/8773/51343/7311/23327/6047/10533/8945/10293/6737/23291/10333/7099/8517/114088/4615/10616/929/3309/8452/9666/114609/9903/142678/7334/7316/7097/3551/7321/135892/7428/7335/7096/11059/83737/10273/695/997/4734/63891/10075/9021/9246/8924/9817/10193/51191/7314/5704/6233/821 57 Encephalomyocarditis_virus R-HSA-2559580 Oxidative Stress Induced Senescence 28/785 125/10654 7.892866678143004e-8 4.021433429678291e-7 2.1203033133949296e-7 1030/7311/1432/3725/1019/192670/5599/1021/5600/5606/9448/7316/1029/26523/3456/192669/5608/7157/9261/6045/5594/5609/7314/6233/5595/7867/4194/23043 28 Encephalomyocarditis_virus R-HSA-198323 AKT phosphorylates targets in the cytosol 9/785 14/10654 8.749704090308112e-8 4.4379129755346554e-7 2.3398924167538055e-7 7249/1147/2932/10000/842/572/207/208/84335 9 Encephalomyocarditis_virus R-HSA-2428928 IRS-related events triggered by IGF1R 17/785 52/10654 8.823314553427024e-8 4.455180352986022e-7 2.3489966524110652e-7 5295/54106/8660/5170/4893/5290/2260/3667/3845/5291/8471/2264/5781/30849/5289/208/10818 17 Encephalomyocarditis_virus R-HSA-389357 CD28 dependent PI3K/Akt signaling 11/785 22/10654 1.0769872891683584e-7 5.413784319658802e-7 2.854421198735687e-7 2475/5295/5170/1326/5290/10000/9020/207/208/253260/64223 11 Encephalomyocarditis_virus R-HSA-68886 M Phase 59/785 395/10654 1.1313800579514504e-7 5.66192864557037e-7 2.985255451156108e-7 5716/4000/7514/23165/7311/1460/9883/9972/348995/11130/22995/79023/81929/57122/23636/5903/5347/23225/6232/8021/332/3320/1780/10762/55706/7175/5579/129401/23511/5528/9662/8243/22981/9126/9631/7316/7531/55869/53371/7321/8655/55746/8481/8086/140735/5578/8480/4957/5594/23279/4927/9688/7314/5704/6233/5595/5515/79902/80254 59 Encephalomyocarditis_virus R-HSA-2428924 IGF1R signaling cascade 17/785 53/10654 1.210935164681314e-7 6.033243342615751e-7 3.1810313594795577e-7 5295/54106/8660/5170/4893/5290/2260/3667/3845/5291/8471/2264/5781/30849/5289/208/10818 17 Encephalomyocarditis_virus R-HSA-112399 IRS-mediated signalling 16/785 48/10654 1.5580852034819393e-7 7.728651714187946e-7 4.07493649322427e-7 5295/54106/8660/5170/4893/5290/2260/3667/3845/5291/2264/5781/30849/5289/208/10818 16 Encephalomyocarditis_virus R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 17/785 54/10654 1.6475372560650998e-7 8.065769349257836e-7 4.25268197904218e-7 5295/54106/8660/5170/4893/5290/2260/3667/3845/5291/8471/2264/5781/30849/5289/208/10818 17 Encephalomyocarditis_virus R-HSA-8848021 Signaling by PTK6 17/785 54/10654 1.6475372560650998e-7 8.065769349257836e-7 4.25268197904218e-7 7311/3091/2064/2034/1019/4893/387/1956/3845/7316/595/6774/207/9021/55620/7314/6233 17 Encephalomyocarditis_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 17/785 54/10654 1.6475372560650998e-7 8.065769349257836e-7 4.25268197904218e-7 7311/3091/2064/2034/1019/4893/387/1956/3845/7316/595/6774/207/9021/55620/7314/6233 17 Encephalomyocarditis_virus R-HSA-5654738 Signaling by FGFR2 20/785 73/10654 1.789996508065671e-7 8.725264363991107e-7 4.6004011417135495e-7 5295/8569/7311/3178/4670/4893/5290/3845/4686/7316/5781/22916/5725/6714/5594/10818/7314/6233/5595/5515 20 Encephalomyocarditis_virus R-HSA-190236 Signaling by FGFR 22/785 87/10654 2.0710354793522178e-7 1.0051663576511197e-6 5.299745963496601e-7 5295/8569/7311/3178/4670/4893/5290/2260/3845/4686/7316/2264/5781/22916/5725/6714/5594/10818/7314/6233/5595/5515 22 Encephalomyocarditis_virus R-HSA-389356 CD28 co-stimulation 13/785 33/10654 2.453233598938012e-7 1.1855540911606016e-6 6.25084142670449e-7 2475/5295/5170/1326/5290/10000/9020/207/6714/208/253260/7525/64223 13 Encephalomyocarditis_virus R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 15/785 44/10654 2.7266232296909057e-7 1.3009227782338814e-6 6.859123557295588e-7 355/834/7161/839/1387/843/332/7159/7157/10397/8795/665/8626/835/8797 15 Encephalomyocarditis_virus R-HSA-69231 Cyclin D associated events in G1 15/785 44/10654 2.7266232296909057e-7 1.3009227782338814e-6 6.859123557295588e-7 8454/6500/1030/7311/894/1019/1021/1874/7316/595/1029/6714/7314/6233/5515 15 Encephalomyocarditis_virus R-HSA-69236 G1 Phase 15/785 44/10654 2.7266232296909057e-7 1.3009227782338814e-6 6.859123557295588e-7 8454/6500/1030/7311/894/1019/1021/1874/7316/595/1029/6714/7314/6233/5515 15 Encephalomyocarditis_virus R-HSA-5654736 Signaling by FGFR1 16/785 50/10654 2.957826169082561e-7 1.4052794372940775e-6 7.40934470069982e-7 5295/8569/7311/4893/5290/2260/3845/7316/5781/6714/5594/10818/7314/6233/5595/5515 16 Encephalomyocarditis_virus R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 11/785 24/10654 3.3221188613070136e-7 1.5717251419460913e-6 8.286930728779992e-7 1432/5590/5579/5600/30849/5289/6279/5578/5594/5595/5580 11 Encephalomyocarditis_virus R-HSA-187687 Signalling to ERKs 13/785 34/10654 3.7060167610975804e-7 1.7460145912116636e-6 9.205872949830591e-7 1432/4893/4914/3845/5600/4803/9261/6714/7529/5594/10818/5595/7867 13 Encephalomyocarditis_virus R-HSA-186763 Downstream signal transduction 12/785 29/10654 3.7891954598272254e-7 1.7777642032356065e-6 9.373272979572611e-7 5295/4893/5290/6778/3845/5291/4690/5781/6774/6772/6714/5156 12 Encephalomyocarditis_virus R-HSA-622312 Inflammasomes 10/785 20/10654 4.1716276021040676e-7 1.9490675020619005e-6 1.027647070358897e-6 4210/834/29108/596/351/598/4790/5970/4791/3326 10 Encephalomyocarditis_virus R-HSA-388841 Costimulation by the CD28 family 19/785 70/10654 4.2555446715114345e-7 1.980059214926395e-6 1.0439874705230316e-6 2475/5295/5170/1326/5290/29851/10000/3115/5528/1445/9020/5781/207/6714/208/253260/7525/5515/64223 19 Encephalomyocarditis_virus R-HSA-205043 NRIF signals cell death from the nucleus 9/785 16/10654 4.3674571558499643e-7 2.0237682129576376e-6 1.0670330673161706e-6 7311/4804/5599/7316/4803/7189/8878/7314/6233 9 Encephalomyocarditis_virus R-HSA-8878166 Transcriptional regulation by RUNX2 26/785 121/10654 5.445494471416997e-7 2.512961792957188e-6 1.3249606910609087e-6 5716/8454/6500/57154/7311/367/7291/2932/1019/10000/7316/595/11059/10273/207/10413/6772/6714/2099/5594/208/7314/5704/6233/7525/5595 26 Encephalomyocarditis_virus R-HSA-1643713 Signaling by EGFR in Cancer 11/785 25/10654 5.539163822492413e-7 2.545754475153656e-6 1.3422506534417705e-6 5295/7311/4893/1956/5290/3320/3845/7316/11140/7314/6233 11 Encephalomyocarditis_virus R-HSA-5218921 VEGFR2 mediated cell proliferation 10/785 21/10654 7.439674484299137e-7 3.405314418423101e-6 1.7954541759284183e-6 5170/3708/5590/4893/3845/5579/8877/5578/6714/5580 10 Encephalomyocarditis_virus R-HSA-8939211 ESR-mediated signaling 38/785 223/10654 8.610724600806384e-7 3.922765044741663e-6 2.0682803451755615e-6 5295/3315/7514/1025/5170/27161/3725/1387/10499/596/5590/1386/4893/1956/5290/192670/10000/3320/3845/2100/2309/8243/9126/595/26523/192669/8202/8877/207/2288/2289/6714/2099/5594/208/4609/5595/3326 38 Encephalomyocarditis_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 19/785 73/10654 8.639837753960323e-7 3.922765044741663e-6 2.0682803451755615e-6 7514/57154/1025/1030/7311/23327/23645/5590/387/1874/7316/23439/7321/10273/4087/5499/4609/7314/6233 19 Encephalomyocarditis_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 11/785 26/10654 8.965164715094716e-7 4.043242069178035e-6 2.1318019323328152e-6 7514/57154/7311/23327/23645/7316/10273/4087/5499/7314/6233 11 Encephalomyocarditis_virus R-HSA-5654733 Negative regulation of FGFR4 signaling 12/785 31/10654 8.977002817890843e-7 4.043242069178035e-6 2.1318019323328152e-6 8569/7311/7316/2264/5781/6714/5594/10818/7314/6233/5595/5515 12 Encephalomyocarditis_virus R-HSA-450341 Activation of the AP-1 family of transcription factors 7/785 10/10654 1.1321110172830576e-6 5.078713169166226e-6 2.6777547232025355e-6 1432/3725/1386/5599/5600/5594/5595 7 Encephalomyocarditis_virus R-HSA-5205685 Pink/Parkin Mediated Mitophagy 10/785 22/10654 1.274191381357474e-6 5.6934106960655386e-6 3.001854382145428e-6 7311/84557/9474/7316/65018/9140/81631/8878/7314/6233 10 Encephalomyocarditis_virus R-HSA-5673000 RAF activation 12/785 32/10654 1.3407093384552202e-6 5.9669514430852885e-6 3.1460789136207374e-6 818/4893/4140/3845/5528/369/8315/4296/5894/6714/7529/5515 12 Encephalomyocarditis_virus R-HSA-111471 Apoptotic factor-mediated response 9/785 18/10654 1.6217086630736485e-6 7.18914942764145e-6 3.7904835722069535e-6 840/836/331/1029/842/54205/5594/578/5595 9 Encephalomyocarditis_virus R-HSA-111465 Apoptotic cleavage of cellular proteins 13/785 38/10654 1.639492894679693e-6 7.239486272193468e-6 3.817023705260462e-6 4000/6093/839/329/840/841/999/5588/836/51765/1499/7082/5580 13 Encephalomyocarditis_virus R-HSA-109704 PI3K Cascade 14/785 44/10654 1.7694466958952812e-6 7.782800701476901e-6 4.10348658094136e-6 5295/54106/8660/5170/5290/2260/3667/5291/2264/5781/30849/5289/208/10818 14 Encephalomyocarditis_virus R-HSA-5654726 Negative regulation of FGFR1 signaling 12/785 33/10654 1.9666441833474476e-6 8.616503309140959e-6 4.5430568069136216e-6 8569/7311/2260/7316/5781/6714/5594/10818/7314/6233/5595/5515 12 Encephalomyocarditis_virus R-HSA-74752 Signaling by Insulin receptor 19/785 78/10654 2.563242652162321e-6 1.1186865218351835e-5 5.898281745489797e-6 5295/54106/8660/5170/4893/5290/2260/3667/3845/5291/2264/5781/3630/30849/5289/5594/208/10818/5595 19 Encephalomyocarditis_virus R-HSA-1236394 Signaling by ERBB4 16/785 58/10654 2.745996297515526e-6 1.193819239769298e-5 6.294419474898422e-6 5295/7311/23118/4893/1956/5290/3845/7316/11059/83737/4734/10413/6714/2099/7314/6233 16 Encephalomyocarditis_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 23/785 108/10654 2.871968932497746e-6 1.2437834684586391e-5 6.557856185946271e-6 5295/7124/2308/3091/7291/596/598/6778/3576/332/3320/2309/595/6774/3569/7157/356/4170/207/9021/6772/4609/4582 23 Encephalomyocarditis_virus R-HSA-8934903 Receptor Mediated Mitophagy 7/785 11/10654 2.914852071688982e-6 1.2527188674510662e-5 6.6049681335178215e-6 8408/1460/84557/9474/9140/81631/6714 7 Encephalomyocarditis_virus R-HSA-9614399 Regulation of localization of FOXO transcription factors 7/785 11/10654 2.914852071688982e-6 1.2527188674510662e-5 6.6049681335178215e-6 2308/10000/2309/207/7529/208/4303 7 Encephalomyocarditis_virus R-HSA-195258 RHO GTPase Effectors 48/785 327/10654 2.9278900000593754e-6 1.2535376958429113e-5 6.6092854113807795e-6 7514/23191/6093/57120/5170/367/1432/348995/11130/79023/10499/81929/57122/5590/5903/1072/5347/387/999/6232/332/1780/5579/5600/5528/3895/1499/7531/4690/8655/30849/5289/55746/2316/695/140735/6279/10458/4771/5578/6714/7529/5594/23279/5595/5515/5580/79902 48 Encephalomyocarditis_virus R-HSA-5674135 MAP2K and MAPK activation 13/785 40/10654 3.1727835356908617e-6 1.3532402504499662e-5 7.134967759687585e-6 5037/4893/4140/8649/3845/369/1445/5894/6714/7529/5594/28956/5595 13 Encephalomyocarditis_virus R-HSA-5654732 Negative regulation of FGFR3 signaling 11/785 29/10654 3.269066494432366e-6 1.3890448576342808e-5 7.323747777000415e-6 8569/7311/7316/5781/6714/5594/10818/7314/6233/5595/5515 11 Encephalomyocarditis_virus R-HSA-3371571 HSF1-dependent transactivation 10/785 24/10654 3.3731393619243466e-6 1.4223312096676579e-5 7.499250278139283e-6 2475/818/3303/1387/3320/57521/2288/84335/3326/64223 10 Encephalomyocarditis_virus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 10/785 24/10654 3.3731393619243466e-6 1.4223312096676579e-5 7.499250278139283e-6 7514/596/1956/10000/2309/595/207/5594/208/5595 10 Encephalomyocarditis_virus R-HSA-844456 The NLRP3 inflammasome 8/785 15/10654 3.385299859599754e-6 1.4223312096676579e-5 7.499250278139283e-6 4210/834/29108/351/4790/5970/4791/3326 8 Encephalomyocarditis_virus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 14/785 47/10654 4.270378494668601e-6 1.7678110974253105e-5 9.320795166381933e-6 5037/818/4893/4140/3845/369/1445/8315/4296/5894/6714/7529/5594/5595 14 Encephalomyocarditis_virus R-HSA-6802949 Signaling by RAS mutants 14/785 47/10654 4.270378494668601e-6 1.7678110974253105e-5 9.320795166381933e-6 5037/818/4893/4140/3845/369/1445/8315/4296/5894/6714/7529/5594/5595 14 Encephalomyocarditis_virus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 14/785 47/10654 4.270378494668601e-6 1.7678110974253105e-5 9.320795166381933e-6 5037/818/4893/4140/3845/369/1445/8315/4296/5894/6714/7529/5594/5595 14 Encephalomyocarditis_virus R-HSA-9649948 Signaling downstream of RAS mutants 14/785 47/10654 4.270378494668601e-6 1.7678110974253105e-5 9.320795166381933e-6 5037/818/4893/4140/3845/369/1445/8315/4296/5894/6714/7529/5594/5595 14 Encephalomyocarditis_virus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 20/785 88/10654 4.449310899837132e-6 1.8351370231562673e-5 9.675771534637142e-6 8454/6500/7311/8945/22995/10133/5347/23291/3320/9662/22981/7316/7531/8655/8481/6790/4957/7314/6233/80254 20 Encephalomyocarditis_virus R-HSA-167044 Signalling to RAS 9/785 20/10654 4.895566180991602e-6 2.0118275619695418e-5 1.0607373515479307e-5 1432/4893/4914/3845/5600/4803/9261/6714/7867 9 Encephalomyocarditis_virus R-HSA-8878159 Transcriptional regulation by RUNX3 21/785 96/10654 4.931473224970352e-6 2.0192141277514968e-5 1.0646319230175229e-5 5716/57154/7311/8463/1387/3845/2309/7316/595/1499/2648/10018/1029/7157/10413/3676/6714/4609/7314/5704/6233 21 Encephalomyocarditis_virus R-HSA-73893 DNA Damage Bypass 14/785 48/10654 5.624862894097478e-6 2.2947810212875942e-5 1.209924741522112e-5 7311/6119/6118/9636/7706/1642/6117/7316/7398/9246/9100/57599/7314/6233 14 Encephalomyocarditis_virus R-HSA-9614657 FOXO-mediated transcription of cell death genes 8/785 16/10654 6.333854003614511e-6 2.5747002195198338e-5 1.3575123154241248e-5 2308/1387/6794/2309/65018/10018/356/4303 8 Encephalomyocarditis_virus R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 7/785 12/10654 6.5501831910887505e-6 2.6372460936954466e-5 1.3904896670507919e-5 834/7161/839/843/7157/8626/835 7 Encephalomyocarditis_virus R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 7/785 12/10654 6.5501831910887505e-6 2.6372460936954466e-5 1.3904896670507919e-5 355/7161/7159/7157/8795/8626/8797 7 Encephalomyocarditis_virus R-HSA-9639288 Amino acids regulate mTORC1 15/785 55/10654 6.557983181480684e-6 2.6372460936954466e-5 1.3904896670507919e-5 2475/55004/58528/10325/81929/10670/8649/153129/6009/389541/64121/57521/10542/28956/64223 15 Encephalomyocarditis_virus R-HSA-1236974 ER-Phagosome pathway 19/785 83/10654 6.869721039034172e-6 2.7527778967802414e-5 1.451403883129902e-5 5716/23643/1147/8773/7311/10333/7099/8517/4615/929/114609/7316/7097/3551/7096/695/7314/5704/6233 19 Encephalomyocarditis_virus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 11/785 31/10654 6.97791373006345e-6 2.7862166170395195e-5 1.4690344694870422e-5 1432/3725/1386/5599/5600/5528/6195/9261/5594/5595/5515 11 Encephalomyocarditis_virus R-HSA-8948751 Regulation of PTEN stability and activity 17/785 69/10654 7.2876271751709324e-6 2.8996000704036996e-5 1.528815966820311e-5 5716/7311/1460/331/10000/7316/5728/8658/10273/207/8975/4734/5987/208/7314/5704/6233 17 Encephalomyocarditis_virus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 14/785 49/10654 7.3474053775499544e-6 2.9130910053243834e-5 1.5359290707702648e-5 55571/4850/4848/23019/9337/57472/1874/85456/29883/7157/6790/25904/246175/4849 14 Encephalomyocarditis_virus R-HSA-5684996 MAPK1/MAPK3 signaling 39/785 255/10654 9.438633278478419e-6 3.729088095286561e-5 1.9661640513617094e-5 5716/5037/8660/7311/818/2064/4893/1956/1438/2260/4140/8649/1437/3667/1843/8452/3845/5528/7316/369/1445/2264/8315/5781/4296/3569/5894/1439/6714/7529/5594/5156/10818/7314/5704/6233/28956/5595/5515 39 Encephalomyocarditis_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 11/785 32/10654 9.93073507804873e-6 3.896169929575913e-5 2.0542580539224224e-5 7514/57154/7311/23327/23645/7316/10273/4087/5499/7314/6233 11 Encephalomyocarditis_virus R-HSA-5656169 Termination of translesion DNA synthesis 11/785 32/10654 9.93073507804873e-6 3.896169929575913e-5 2.0542580539224224e-5 7311/6119/6118/9636/7706/6117/7316/9246/9100/7314/6233 11 Encephalomyocarditis_virus R-HSA-6802957 Oncogenic MAPK signaling 17/785 71/10654 1.1004145328569464e-5 4.302315152767089e-5 2.2683983791349335e-5 4000/5037/818/10533/4893/4140/3845/10018/369/1445/8315/4296/5894/6714/7529/5594/5595 17 Encephalomyocarditis_virus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 19/785 86/10654 1.1889094920295129e-5 4.6322217578727734e-5 2.4423418448539257e-5 5295/23191/3708/1072/5290/5581/3320/5291/4690/6850/695/10458/4771/6714/5594/7525/5595/3326/5580 19 Encephalomyocarditis_virus R-HSA-912631 Regulation of signaling by CBL 9/785 22/10654 1.2672008664374268e-5 4.920235088305319e-5 2.5941970550660938e-5 5295/7311/5290/5291/7316/6850/7314/6233/7525 9 Encephalomyocarditis_virus R-HSA-111461 Cytochrome c-mediated apoptotic response 7/785 13/10654 1.3289312332558247e-5 5.1245772898837625e-5 2.7019366097919432e-5 840/836/331/842/54205/5594/5595 7 Encephalomyocarditis_virus R-HSA-171007 p38MAPK events 7/785 13/10654 1.3289312332558247e-5 5.1245772898837625e-5 2.7019366097919432e-5 1432/4893/3845/5600/9261/6714/7867 7 Encephalomyocarditis_virus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 21/785 102/10654 1.3409183033357901e-5 5.153153616232422e-5 2.717003495891452e-5 5716/8454/6500/7124/1147/330/7311/7132/8945/329/7187/23291/7186/958/7316/9020/356/4791/7314/5704/6233 21 Encephalomyocarditis_virus R-HSA-9614085 FOXO-mediated transcription 16/785 65/10654 1.3657406508677367e-5 5.2306937852961616e-5 2.7578865989595543e-5 2308/1387/4287/10000/6794/2309/65018/10018/3630/3066/356/207/4087/7529/208/4303 16 Encephalomyocarditis_virus R-HSA-75153 Apoptotic execution phase 14/785 52/10654 1.5636430926962646e-5 5.968346177545742e-5 3.146814288245115e-5 4000/6093/839/329/840/841/999/5588/836/51765/1499/7082/3146/5580 14 Encephalomyocarditis_virus R-HSA-5654727 Negative regulation of FGFR2 signaling 11/785 34/10654 1.9209791165362104e-5 7.307508396012747e-5 3.852888412967364e-5 8569/7311/7316/5781/6714/5594/10818/7314/6233/5595/5515 11 Encephalomyocarditis_virus R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 7/785 14/10654 2.488978489005252e-5 9.43632922094247e-5 4.975310536235911e-5 7161/10000/7159/7157/207/8626/208 7 Encephalomyocarditis_virus R-HSA-418889 Caspase activation via Dependence Receptors in the absence of ligand 6/785 10/10654 2.5490898928831944e-5 9.631796038209654e-5 5.078370538983122e-5 1613/23604/1630/836/1612/842 6 Encephalomyocarditis_virus R-HSA-114604 GPVI-mediated activation cascade 11/785 35/10654 2.61669807050534e-5 9.85418738257195e-5 5.195626515631093e-5 5295/5170/146850/5590/23533/387/5290/5294/5291/5781/6850 11 Encephalomyocarditis_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 13/785 48/10654 2.928974058774638e-5 1.0993415967267475e-4 5.796285505785599e-5 5295/7311/1438/5290/1437/5291/7316/5781/6850/1439/7314/6233/7525 13 Encephalomyocarditis_virus R-HSA-453279 Mitotic G1-G1/S phases 26/785 149/10654 2.997381222095213e-5 1.1212794870695049e-4 5.9119531710498345e-5 5716/8454/6500/1030/7311/6119/6118/894/1019/10000/6117/1021/1874/7316/595/1029/207/6714/4171/208/4609/7314/5704/6233/5515/7298 26 Encephalomyocarditis_virus R-HSA-5686938 Regulation of TLR by endogenous ligand 8/785 19/10654 3.0463964398401516e-5 1.1342521472974109e-4 5.980351603961295e-5 23643/10333/7099/929/7097/7096/6279/3146 8 Encephalomyocarditis_virus R-HSA-5673001 RAF/MAP kinase cascade 37/785 249/10654 3.05220604468131e-5 1.1342521472974109e-4 5.980351603961295e-5 5716/5037/8660/7311/818/2064/4893/1956/1438/2260/4140/8649/1437/3667/1843/8452/3845/5528/7316/369/1445/2264/8315/4296/5894/1439/6714/7529/5594/5156/10818/7314/5704/6233/28956/5595/5515 37 Encephalomyocarditis_virus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 10/785 30/10654 3.439619655098306e-5 1.2740170169870697e-4 6.7172627613415665e-005 7311/6119/6118/1642/6117/7316/7398/57599/7314/6233 10 Encephalomyocarditis_virus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 11/785 36/10654 3.519711004167308e-5 1.2994080625220946e-4 6.851137209147065e-5 5037/4893/4140/3845/369/1445/5894/6714/7529/5594/5595 11 Encephalomyocarditis_virus R-HSA-111447 Activation of BAD and translocation to mitochondria 7/785 15/10654 4.3706209291698736e-5 1.5978308981315836e-4 8.42457349300003e-5 596/10000/7531/572/207/7529/208 7 Encephalomyocarditis_virus R-HSA-5637810 Constitutive Signaling by EGFRvIII 7/785 15/10654 4.3706209291698736e-5 1.5978308981315836e-4 8.42457349300003e-5 5295/4893/1956/5290/3320/3845/11140 7 Encephalomyocarditis_virus R-HSA-5637812 Signaling by EGFRvIII in Cancer 7/785 15/10654 4.3706209291698736e-5 1.5978308981315836e-4 8.42457349300003e-5 5295/4893/1956/5290/3320/3845/11140 7 Encephalomyocarditis_virus R-HSA-9006936 Signaling by TGF-beta family members 20/785 102/10654 4.498602614063343e-5 1.6392966159984869e-4 8.643201752109439e-5 7514/57154/1025/1030/7311/23327/23645/5590/387/1874/7316/23439/7321/10273/4087/5499/4609/7314/657/6233 20 Encephalomyocarditis_virus R-HSA-5655291 Signaling by FGFR4 in disease 6/785 11/10654 5.258215515740354e-5 1.9099195712011738e-4 1.0070062991095279e-4 5295/4893/5290/3845/2264/10818 6 Encephalomyocarditis_virus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 12/785 44/10654 5.492757418113424e-5 1.9886960941465322e-4 1.0485412705418756e-4 1025/1030/7311/23327/1874/7316/23439/7321/4087/4609/7314/6233 12 Encephalomyocarditis_virus R-HSA-5696394 DNA Damage Recognition in GG-NER 11/785 38/10654 6.151598587373617e-5 2.2200961568534272e-4 1.1705470996217005e-4 7311/8533/1642/7316/10987/5886/50813/7314/10445/6233/51138 11 Encephalomyocarditis_virus R-HSA-1980143 Signaling by NOTCH1 16/785 73/10654 6.366493722298884e-5 2.290310521184838e-4 1.2075676675219676e-4 8454/6500/7311/3091/1387/57534/142678/7316/2648/55869/3066/83737/4609/7314/6233/23220 16 Encephalomyocarditis_virus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 10/785 32/10654 6.450787926096251e-5 2.3132443327338785e-4 1.219659534132848e-4 1025/1030/7311/1874/7316/23439/4087/4609/7314/6233 10 Encephalomyocarditis_virus R-HSA-5687128 MAPK6/MAPK4 signaling 18/785 89/10654 7.00202774784587e-5 2.5029470616109366e-4 1.3196804176391215e-4 5716/3315/7514/2308/7311/27161/3725/192670/2309/7316/26523/192669/8202/5597/4609/7314/5704/6233 18 Encephalomyocarditis_virus R-HSA-389513 CTLA4 inhibitory signaling 8/785 21/10654 7.181743888975895e-5 2.5509916779138355e-4 1.3450119719018446e-4 10000/5528/5781/207/6714/208/7525/5515 8 Encephalomyocarditis_virus R-HSA-9008059 Interleukin-37 signaling 8/785 21/10654 7.181743888975895e-5 2.5509916779138355e-4 1.3450119719018446e-4 834/84867/5781/27178/6774/59307/29110/8809 8 Encephalomyocarditis_virus R-HSA-110312 Translesion synthesis by REV1 7/785 16/10654 7.27735967379864e-5 2.568748273572812e-4 1.3543741481677723e-4 7311/6119/6118/6117/7316/7314/6233 7 Encephalomyocarditis_virus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 7/785 16/10654 7.27735967379864e-5 2.568748273572812e-4 1.3543741481677723e-4 57154/7311/5590/387/7316/7314/6233 7 Encephalomyocarditis_virus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 42/785 309/10654 7.735391189616004e-5 2.721890774846131e-4 1.4351186285998117e-4 7322/5716/8454/6500/57154/51343/7311/23327/6047/10533/8945/10293/6737/23291/114088/10616/8452/9666/9903/142678/7334/7316/7321/135892/7428/7335/11059/83737/10273/997/4734/63891/10075/9021/9246/8924/9817/10193/51191/7314/5704/6233 42 Encephalomyocarditis_virus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 11/785 39/10654 8.00454837739408e-5 2.807826004032939e-4 1.480428032415236e-4 7311/6119/6118/9636/7706/6117/7316/9246/9100/7314/6233 11 Encephalomyocarditis_virus R-HSA-6802952 Signaling by BRAF and RAF fusions 15/785 67/10654 8.28491446984867e-5 2.897147109642734e-4 1.5275226417112294e-4 4000/5037/818/10533/4893/4140/3845/10018/369/1445/5894/6714/7529/5594/5595 15 Encephalomyocarditis_virus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 14/785 60/10654 8.819573417742974e-5 3.0712245007197606e-4 1.619305056002566e-4 5716/8454/6500/1147/7311/8945/23291/7316/9020/5970/4791/7314/5704/6233 14 Encephalomyocarditis_virus R-HSA-8854214 TBC/RABGAPs 12/785 46/10654 8.837271209886345e-5 3.0712245007197606e-4 1.619305056002566e-4 7249/8408/10133/11345/338382/5868/9363/7248/81631/7879/11337/51256 12 Encephalomyocarditis_virus R-HSA-1234174 Cellular response to hypoxia 16/785 75/10654 8.985758294339748e-5 3.1036698893946495e-4 1.636411907655027e-4 7322/5716/7311/3091/1387/2034/55662/7316/112399/7321/405/7428/7314/5704/6233/8994 16 Encephalomyocarditis_virus R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 16/785 75/10654 8.985758294339748e-5 3.1036698893946495e-4 1.636411907655027e-4 5295/8660/2064/1956/5290/2260/29851/3667/2100/5291/2264/5781/6714/2099/5156/10818 16 Encephalomyocarditis_virus R-HSA-1236975 Antigen processing-Cross presentation 19/785 99/10654 9.385962751381863e-5 3.231985950475834e-4 1.7040666318298312e-4 5716/23643/1147/8773/7311/10333/7099/8517/4615/929/114609/7316/7097/3551/7096/695/7314/5704/6233 19 Encephalomyocarditis_virus R-HSA-170968 Frs2-mediated activation 6/785 12/10654 9.86141271237182e-5 3.354667889465459e-4 1.7687507615766278e-4 4914/4803/7529/5594/10818/5595 6 Encephalomyocarditis_virus R-HSA-3371511 HSF1 activation 6/785 12/10654 9.86141271237182e-5 3.354667889465459e-4 1.7687507615766278e-4 6119/6118/3320/6117/7531/3326 6 Encephalomyocarditis_virus R-HSA-5689877 Josephin domain DUBs 6/785 12/10654 9.86141271237182e-5 3.354667889465459e-4 1.7687507615766278e-4 7311/4287/7316/5886/7314/6233 6 Encephalomyocarditis_virus R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 6/785 12/10654 9.86141271237182e-5 3.354667889465459e-4 1.7687507615766278e-4 5295/8660/23533/5290/5294/5291 6 Encephalomyocarditis_virus R-HSA-6783310 Fanconi Anemia Pathway 11/785 40/10654 1.0314747920851031e-4 3.498315108095862e-4 1.8444888482434946e-4 7311/6119/6118/2189/6117/2175/7316/7398/57599/7314/6233 11 Encephalomyocarditis_virus R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 8/785 22/10654 1.0561482758997896e-4 3.560547780428632e-4 1.8773010640008866e-4 4000/3725/351/2309/10018/7531/356/823 8 Encephalomyocarditis_virus R-HSA-8863678 Neurodegenerative Diseases 8/785 22/10654 1.0561482758997896e-4 3.560547780428632e-4 1.8773010640008866e-4 4000/3725/351/2309/10018/7531/356/823 8 Encephalomyocarditis_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 12/785 47/10654 1.1082718383137113e-4 3.725116686391758e-4 1.964070123515894e-4 8454/6500/7311/3091/1387/7316/2648/55869/3066/4609/7314/6233 12 Encephalomyocarditis_virus R-HSA-5655862 Translesion synthesis by POLK 7/785 17/10654 1.15880111529548e-4 3.8718399282573014e-4 2.0414300453745144e-4 7311/6119/6118/6117/7316/7314/6233 7 Encephalomyocarditis_virus R-HSA-5656121 Translesion synthesis by POLI 7/785 17/10654 1.15880111529548e-4 3.8718399282573014e-4 2.0414300453745144e-4 7311/6119/6118/6117/7316/7314/6233 7 Encephalomyocarditis_virus R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 20/785 110/10654 1.356980833015198e-4 4.5205929525890916e-4 2.3834854868283144e-4 1030/51343/7311/3725/1019/3576/3490/4790/1021/7316/6195/1029/7321/6774/3569/5970/5594/7314/6233/5595 20 Encephalomyocarditis_virus R-HSA-68877 Mitotic Prometaphase 30/785 200/10654 1.4217768868726084e-4 4.7224801611166873e-4 2.4899306449189607e-4 7514/1460/348995/11130/22995/79023/81929/57122/5903/5347/6232/332/3320/1780/5528/9662/8243/22981/9126/7531/55869/8655/55746/8481/140735/4957/23279/5515/79902/80254 30 Encephalomyocarditis_virus R-HSA-5218920 VEGFR2 mediated vascular permeability 9/785 29/10654 1.5952155595366896e-4 5.282978588347977e-4 2.785453794361278e-4 2475/5170/10000/3320/1499/207/208/253260/64223 9 Encephalomyocarditis_virus R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 11/785 42/10654 1.6671772768428106e-4 5.505107371627581e-4 2.9025713355127186e-4 7514/7311/8945/331/7316/1499/207/208/7314/6233/5929 11 Encephalomyocarditis_virus R-HSA-177929 Signaling by EGFR 12/785 49/10654 1.7069594345277248e-4 5.619989249351514e-4 2.963142878035201e-4 5295/7311/4893/1956/5290/3845/7316/1445/5781/6714/7314/6233 12 Encephalomyocarditis_virus R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 7/785 18/10654 1.7762668394496046e-4 5.831126709096953e-4 3.07446523691753e-4 4893/1956/3845/6195/5578/5594/5595 7 Encephalomyocarditis_virus R-HSA-141424 Amplification of signal from the kinetochores 18/785 96/10654 1.9382568857825923e-4 6.326021024322315e-4 3.3353985769073445e-4 7514/348995/11130/79023/81929/57122/5903/5347/6232/332/1780/5528/8655/55746/140735/23279/5515/79902 18 Encephalomyocarditis_virus R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 18/785 96/10654 1.9382568857825923e-4 6.326021024322315e-4 3.3353985769073445e-4 7514/348995/11130/79023/81929/57122/5903/5347/6232/332/1780/5528/8655/55746/140735/23279/5515/79902 18 Encephalomyocarditis_virus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 15/785 72/10654 1.9587031791177027e-4 6.374276819903276e-4 3.360841475577683e-4 51422/8773/5563/5571/53632/7531/5564/60412/5565/207/149371/7529/208/55770/23265 15 Encephalomyocarditis_virus R-HSA-982772 Growth hormone receptor signaling 8/785 24/10654 2.1278302548752637e-4 6.904717195935294e-4 3.640516498558013e-4 8660/3667/8835/6774/9021/6772/5594/5595 8 Encephalomyocarditis_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 15/785 73/10654 2.300613646416278e-4 7.443939557082555e-4 3.9248218287319444e-4 5716/8454/6500/57154/7311/7291/2932/7316/11059/10273/6772/2099/7314/5704/6233 15 Encephalomyocarditis_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 13/785 58/10654 2.4093963118535023e-4 7.685496450841484e-4 4.0521828533930985e-4 8454/6500/7311/1387/57534/142678/7316/2648/55869/3066/4609/7314/6233 13 Encephalomyocarditis_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 13/785 58/10654 2.4093963118535023e-4 7.685496450841484e-4 4.0521828533930985e-4 8454/6500/7311/1387/57534/142678/7316/2648/55869/3066/4609/7314/6233 13 Encephalomyocarditis_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 13/785 58/10654 2.4093963118535023e-4 7.685496450841484e-4 4.0521828533930985e-4 8454/6500/7311/1387/57534/142678/7316/2648/55869/3066/4609/7314/6233 13 Encephalomyocarditis_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 13/785 58/10654 2.4093963118535023e-4 7.685496450841484e-4 4.0521828533930985e-4 8454/6500/7311/1387/57534/142678/7316/2648/55869/3066/4609/7314/6233 13 Encephalomyocarditis_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 13/785 58/10654 2.4093963118535023e-4 7.685496450841484e-4 4.0521828533930985e-4 8454/6500/7311/1387/57534/142678/7316/2648/55869/3066/4609/7314/6233 13 Encephalomyocarditis_virus R-HSA-110320 Translesion Synthesis by POLH 7/785 19/10654 2.634716036804535e-4 8.380480953225724e-4 4.418613870822949e-4 7311/6119/6118/6117/7316/7314/6233 7 Encephalomyocarditis_virus R-HSA-169893 Prolonged ERK activation events 6/785 14/10654 2.818946059857076e-4 8.916104672469291e-4 4.701021814782351e-4 4914/4803/7529/5594/10818/5595 6 Encephalomyocarditis_virus R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 6/785 14/10654 2.818946059857076e-4 8.916104672469291e-4 4.701021814782351e-4 7161/332/7159/7157/10397/8626 6 Encephalomyocarditis_virus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 13/785 59/10654 2.885565009980487e-4 9.101249863411844e-4 4.7986397335367676e-4 5716/8454/6500/1147/7311/8945/23291/7316/9020/4791/7314/5704/6233 13 Encephalomyocarditis_virus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 8/785 25/10654 2.9289548419089646e-4 9.161119866637484e-4 4.8302062305165386e-4 1432/5600/5528/6195/9261/5594/5595/5515 8 Encephalomyocarditis_virus R-HSA-392451 G beta:gamma signalling through PI3Kgamma 8/785 25/10654 2.9289548419089646e-4 9.161119866637484e-4 4.8302062305165386e-4 5170/146850/23533/387/10000/5294/207/208 8 Encephalomyocarditis_virus R-HSA-9006335 Signaling by Erythropoietin 8/785 25/10654 2.9289548419089646e-4 9.161119866637484e-4 4.8302062305165386e-4 5295/8660/23533/4893/5290/5294/3845/5291 8 Encephalomyocarditis_virus R-HSA-2467813 Separation of Sister Chromatids 28/785 190/10654 3.1628019606711496e-4 9.865138525528294e-4 5.201400512665196e-4 5716/7514/7311/348995/11130/79023/81929/57122/5903/5347/6232/332/1780/5528/8243/9126/7316/55869/7321/8655/55746/140735/23279/7314/5704/6233/5515/79902 28 Encephalomyocarditis_virus R-HSA-2500257 Resolution of Sister Chromatid Cohesion 21/785 126/10654 3.287457245710937e-4 0.0010225626681410263 5.391468120328493e-4 7514/348995/11130/79023/81929/57122/5903/5347/6232/332/1780/5528/8243/9126/55869/8655/55746/140735/23279/5515/79902 21 Encephalomyocarditis_virus R-HSA-68882 Mitotic Anaphase 29/785 201/10654 3.5827678180214124e-4 0.001111348915452372 5.859594169534803e-4 5716/4000/7514/7311/348995/11130/79023/81929/57122/5903/5347/6232/332/1780/5528/8243/9126/7316/55869/7321/8655/55746/140735/23279/7314/5704/6233/5515/79902 29 Encephalomyocarditis_virus R-HSA-2871796 FCERI mediated MAPK activation 9/785 32/10654 3.6561788529477807e-4 0.0011279061338134797 5.946892207822779e-4 3725/4893/3845/5599/6850/5594/5609/5595/4214 9 Encephalomyocarditis_virus R-HSA-397795 G-protein beta:gamma signalling 9/785 32/10654 3.6561788529477807e-4 0.0011279061338134797 5.946892207822779e-4 5170/146850/23533/387/10000/5294/207/695/208 9 Encephalomyocarditis_virus R-HSA-8876384 Listeria monocytogenes entry into host cells 7/785 20/10654 3.7975885624146174e-4 0.0011683291588193605 6.160022862242866e-4 7311/999/7316/1499/6714/7314/6233 7 Encephalomyocarditis_virus R-HSA-2555396 Mitotic Metaphase and Anaphase 29/785 202/10654 3.897800856530336e-4 0.0011958920339109422 6.305348295089946e-4 5716/4000/7514/7311/348995/11130/79023/81929/57122/5903/5347/6232/332/1780/5528/8243/9126/7316/55869/7321/8655/55746/140735/23279/7314/5704/6233/5515/79902 29 Encephalomyocarditis_virus R-HSA-74749 Signal attenuation 5/785 10/10654 3.951823493094921e-4 0.0012058951905758485 6.358090001727388e-4 8660/3667/3630/5594/5595 5 Encephalomyocarditis_virus R-HSA-8853334 Signaling by FGFR3 fusions in cancer 5/785 10/10654 3.951823493094921e-4 0.0012058951905758485 6.358090001727388e-4 5295/4893/5290/3845/10818 5 Encephalomyocarditis_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 16/785 85/10654 4.133215438616084e-4 0.0012578379956437054 6.631958769216136e-4 5716/8454/6500/51343/7311/1019/10000/1874/7316/595/207/208/4609/7314/5704/6233 16 Encephalomyocarditis_virus R-HSA-69620 Cell Cycle Checkpoints 38/785 293/10654 4.361068260669179e-4 0.001323601849464554 6.978699103468342e-4 5716/672/7514/7311/6119/6118/9025/348995/11130/79023/81929/57122/5903/5347/6232/332/1780/6117/5528/7334/7316/7531/1029/7321/8655/7157/55746/140735/8924/7529/4171/23279/7314/5704/6233/5515/79902/4194 38 Encephalomyocarditis_virus R-HSA-2691230 Signaling by NOTCH1 HD Domain Mutants in Cancer 6/785 15/10654 4.406868704483798e-4 0.0013267738399060846 6.995423443087144e-4 7311/57534/142678/7316/7314/6233 6 Encephalomyocarditis_virus R-HSA-2691232 Constitutive Signaling by NOTCH1 HD Domain Mutants 6/785 15/10654 4.406868704483798e-4 0.0013267738399060846 6.995423443087144e-4 7311/57534/142678/7316/7314/6233 6 Encephalomyocarditis_virus R-HSA-430039 mRNA decay by 5' to 3' exoribonuclease 6/785 15/10654 4.406868704483798e-4 0.0013267738399060846 6.995423443087144e-4 1656/80153/54464/27257/167227/27258 6 Encephalomyocarditis_virus R-HSA-69618 Mitotic Spindle Checkpoint 19/785 112/10654 4.955683874620986e-4 0.0014880266780861948 7.845630049926278e-4 7514/348995/11130/79023/81929/57122/5903/5347/6232/332/1780/5528/7321/8655/55746/140735/23279/5515/79902 19 Encephalomyocarditis_virus R-HSA-71387 Metabolism of carbohydrates 38/785 295/10654 4.987327460157683e-4 0.0014935454042919018 7.874727568670026e-4 23165/7311/9883/9972/348995/79023/81929/57122/23636/5903/23225/8021/2597/5836/10762/55706/7175/129401/23511/5528/9631/7316/53371/5230/55746/10165/8086/3098/3161/8480/23279/4927/9688/7314/6233/5515/1468/79902 38 Encephalomyocarditis_virus R-HSA-69275 G2/M Transition 28/785 196/10654 5.288939009392814e-4 0.0015796671948478272 8.32880525282018e-4 5716/8454/6500/7514/7311/8945/22995/10133/5347/23291/3320/9662/22981/7316/7531/8655/7157/8481/6790/22974/3161/4957/7314/5704/6233/5515/3326/80254 28 Encephalomyocarditis_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 7/785 21/10654 5.337295649173132e-4 0.0015898928309441656 8.382719983663733e-4 3384/1387/4893/4790/3845/5970/5894 7 Encephalomyocarditis_virus R-HSA-69206 G1/S Transition 21/785 131/10654 5.632898093101595e-4 0.0016735206471853287 8.823648172501874e-4 5716/8454/6500/7311/6119/6118/1019/10000/6117/1874/7316/595/207/4171/208/4609/7314/5704/6233/5515/7298 21 Encephalomyocarditis_virus R-HSA-453274 Mitotic G2-G2/M phases 28/785 198/10654 6.235249254133128e-4 0.0018476028053036584 9.741497449670594e-4 5716/8454/6500/7514/7311/8945/22995/10133/5347/23291/3320/9662/22981/7316/7531/8655/7157/8481/6790/22974/3161/4957/7314/5704/6233/5515/3326/80254 28 Encephalomyocarditis_virus R-HSA-9006931 Signaling by Nuclear Receptors 38/785 299/10654 6.484181971304069e-4 0.001916322545849969 0.0010103822715334977 5295/3315/7514/1025/5170/27161/3725/1387/10499/596/5590/1386/4893/1956/5290/192670/10000/3320/3845/2100/2309/8243/9126/595/26523/192669/8202/8877/207/2288/2289/6714/2099/5594/208/4609/5595/3326 38 Encephalomyocarditis_virus R-HSA-1059683 Interleukin-6 signaling 5/785 11/10654 6.806825111029004e-4 0.001985617895082554 0.0010469182881429938 5781/6774/3569/9021/6772 5 Encephalomyocarditis_virus R-HSA-111458 Formation of apoptosome 5/785 11/10654 6.806825111029004e-4 0.001985617895082554 0.0010469182881429938 331/842/54205/5594/5595 5 Encephalomyocarditis_virus R-HSA-2586552 Signaling by Leptin 5/785 11/10654 6.806825111029004e-4 0.001985617895082554 0.0010469182881429938 8660/3667/5781/6774/9021 5 Encephalomyocarditis_virus R-HSA-4755510 SUMOylation of immune response proteins 5/785 11/10654 6.806825111029004e-4 0.001985617895082554 0.0010469182881429938 8517/9641/5970/4792/4791 5 Encephalomyocarditis_virus R-HSA-9627069 Regulation of the apoptosome activity 5/785 11/10654 6.806825111029004e-4 0.001985617895082554 0.0010469182881429938 331/842/54205/5594/5595 5 Encephalomyocarditis_virus R-HSA-69242 S Phase 24/785 161/10654 6.998450947151302e-4 0.0020362418001272265 0.001073609774022395 5716/8454/6500/51343/7311/6119/6118/2932/1019/10000/6117/1874/8243/9126/7316/595/7321/207/4171/208/4609/7314/5704/6233 24 Encephalomyocarditis_virus R-HSA-1250196 SHC1 events in ERBB2 signaling 7/785 22/10654 7.335164423367365e-4 0.002117793625823501 0.001116608025581429 2064/4893/1956/5581/3845/5578/5580 7 Encephalomyocarditis_virus R-HSA-198753 ERK/MAPK targets 7/785 22/10654 7.335164423367365e-4 0.002117793625823501 0.001116608025581429 1432/5600/5528/6195/5594/5595/5515 7 Encephalomyocarditis_virus R-HSA-9613829 Chaperone Mediated Autophagy 7/785 22/10654 7.335164423367365e-4 0.002117793625823501 0.001116608025581429 7311/3920/3320/7316/7314/6233/3326 7 Encephalomyocarditis_virus R-HSA-438064 Post NMDA receptor activation events 15/785 81/10654 7.418416010236375e-4 0.002136352027500296 0.0011263929545762056 51422/818/5170/5563/5571/5562/53632/4893/3845/6195/5564/5565/6714/5594/5595 15 Encephalomyocarditis_virus R-HSA-186797 Signaling by PDGF 12/785 58/10654 8.936541881521643e-4 0.0025669760608656557 0.001353439747899626 5295/4893/5290/6778/3845/5291/4690/5781/6774/6772/6714/5156 12 Encephalomyocarditis_virus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 13/785 66/10654 9.031249651118077e-4 0.0025875794165798865 0.0013643028802010433 7322/5716/7311/3091/2034/7316/112399/7321/7428/7314/5704/6233/8994 13 Encephalomyocarditis_virus R-HSA-1433557 Signaling by SCF-KIT 10/785 43/10654 9.139554767119163e-4 0.0026053515614623234 0.0013736732548048525 5295/4893/5290/3845/5781/6774/5578/6772/6714/7525 10 Encephalomyocarditis_virus R-HSA-5696395 Formation of Incision Complex in GG-NER 10/785 43/10654 9.139554767119163e-4 0.0026053515614623234 0.0013736732548048525 7311/6119/6118/1642/6117/7334/7316/5886/7314/6233 10 Encephalomyocarditis_virus R-HSA-180292 GAB1 signalosome 6/785 17/10654 9.590101382082905e-4 0.002720013641366587 0.0014341289087882163 5295/1956/5290/1445/5781/6714 6 Encephalomyocarditis_virus R-HSA-9034015 Signaling by NTRK3 (TRKC) 6/785 17/10654 9.590101382082905e-4 0.002720013641366587 0.0014341289087882163 5295/4893/5290/3667/3845/6714 6 Encephalomyocarditis_virus R-HSA-69202 Cyclin E associated events during G1/S transition 15/785 83/10654 9.656373040570097e-4 0.0027319286541914395 0.0014404111068187081 5716/8454/6500/7311/1019/10000/1874/7316/595/207/208/4609/7314/5704/6233 15 Encephalomyocarditis_virus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 7/785 23/10654 9.881216294017386e-4 0.0027885337210685657 0.0014702561640484915 7311/23327/7316/7321/4087/7314/6233 7 Encephalomyocarditis_virus R-HSA-877300 Interferon gamma signaling 16/785 92/10654 0.0010208605227791812 0.0028737223716233952 0.0015151719338091006 3665/818/10107/6737/7706/3115/7726/3663/5781/3661/10346/9021/5371/6772/9830/5580 16 Encephalomyocarditis_virus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 15/785 84/10654 0.001097390352697623 0.0030814502173005572 0.0016246965715224029 7311/6119/6118/8533/1642/6117/7334/7316/10987/5886/50813/7314/10445/6233/51138 15 Encephalomyocarditis_virus R-HSA-204998 Cell death signalling via NRAGE, NRIF and NADE 14/785 76/10654 0.0011627135533296966 0.0032567548782319366 0.0017171260646188765 7311/4804/836/5599/7316/4803/10018/7531/572/7189/835/8878/7314/6233 14 Encephalomyocarditis_virus R-HSA-210993 Tie2 Signaling 6/785 18/10654 0.0013497018653399538 0.0037617928227049206 0.001983407639530313 5295/4893/5290/3845/5291/5781 6 Encephalomyocarditis_virus R-HSA-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 6/785 18/10654 0.0013497018653399538 0.0037617928227049206 0.001983407639530313 330/329/7187/7186/958/9020 6 Encephalomyocarditis_virus R-HSA-2122948 Activated NOTCH1 Transmits Signal to the Nucleus 8/785 31/10654 0.0014387582518762057 0.004000103189166933 0.002109056930625549 7311/57534/142678/7316/83737/7314/6233/23220 8 Encephalomyocarditis_virus R-HSA-2029485 Role of phospholipids in phagocytosis 7/785 25/10654 0.0017018999528170267 0.004685426275970592 0.0024703939605940114 5295/3708/5290/5581/5291/6850/5580 7 Encephalomyocarditis_virus R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 7/785 25/10654 0.0017018999528170267 0.004685426275970592 0.0024703939605940114 7311/6119/6118/6117/7316/7314/6233 7 Encephalomyocarditis_virus R-HSA-9006115 Signaling by NTRK2 (TRKB) 7/785 25/10654 0.0017018999528170267 0.004685426275970592 0.0024703939605940114 5295/4893/5290/3845/5781/6714/10818 7 Encephalomyocarditis_virus R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus 7/785 25/10654 0.0017018999528170267 0.004685426275970592 0.0024703939605940114 7311/57534/1956/142678/7316/7314/6233 7 Encephalomyocarditis_virus R-HSA-381042 PERK regulates gene expression 8/785 32/10654 0.0017964717074033477 0.004933724737893097 0.002601309481323461 9709/3576/8894/3309/1965/5073/167227/1968 8 Epstein.Barr_virus R-HSA-449147 Signaling by Interleukins 415/5894 461/10654 7.153976130719284e-62 1.0065644415922033e-58 3.644762576071719e-59 5295/729230/8454/3605/7124/2308/834/1052/5689/3725/7291/5777/9252/1437/4790/5682/5291/1511/5657/5783/27178/1848/356/3593/246/9021/8878/6624/5908/3082/5743/3091/941/1265/143471/10538/3383/5705/11009/6097/6349/6657/3576/3313/3662/6776/3688/4985/5709/9978/6175/2920/5695/84868/1435/4792/3936/59307/7133/3606/177/4609/3603/5898/5711/4988/1432/3558/3717/4088/836/5683/200081/2534/84867/2162/5699/3181/5702/4001/3654/3563/2885/85480/51135/8660/282618/6196/3594/1154/50604/9846/6347/5518/282617/1386/55540/6382/9235/7040/3588/6197/4282/7334/3600/3312/1399/3551/55801/3569/5062/5696/5691/51231/4692/7314/3572/3596/5515/257397/3598/5718/54014/10148/8945/1326/5601/1072/3635/3592/5290/3667/6627/6283/5606/90865/64109/9049/11213/3587/7412/5700/122706/5707/27250/8767/3911/1849/29110/1439/5594/4582/23198/28512/23118/6367/4312/9987/8517/6778/7534/6810/332/5528/4313/3565/3934/3976/50615/3185/5970/5443/9261/3718/3627/8807/8809/9861/149233/5519/5598/4208/3567/598/2247/5698/5692/5713/2335/595/6195/5710/3458/10454/7157/5478/5719/6233/7525/4128/6844/7409/2353/604/6809/3932/7076/302/552900/51561/3570/8835/5600/6777/6773/7850/7297/5781/5608/4791/1846/59067/3557/56300/9655/3562/351/6464/3566/6597/5782/6351/7184/3589/6775/50616/3684/9446/3595/54472/821/4318/5706/3726/58480/301/4478/1438/53833/3581/6616/79155/6774/920/6850/5780/1440/5714/6772/8651/7867/5566/64127/8503/1901/3552/2889/5688/79923/5687/4067/29760/3636/5708/5602/29949/3656/57162/5771/998/6648/116379/7189/163702/112744/6654/5704/7006/3716/84639/7311/2939/1270/6888/5293/2185/240/6356/5008/5694/23765/246778/6416/1234/3586/3554/829/28511/5595/3556/5516/6095/1147/5778/1845/596/5055/5684/2208/5720/6885/2309/5604/4215/3561/3578/3590/10392/207/5292/5451/7422/5690/3553/2625/1230/5717/2919/9491/6500/3568/25930/10197/4615/3597/2357/1436/26525/7316/10213/3560/6352/4314/7335/1441/4205/3055/1026/6348/4793/5775/3146/6647/6364/5715/7132/5701/867/466/6950/23291/5685/3320/5686/4843/9466/6288/2002/942/6285/5609/1398/58985/948/5716/1385/9173/53832/6363/3575/4507/6845/5896/5296/6935/3687/5599/5784/7431/375/3977/3559/3574/3929/3162/1489/57161/1278/4170/5693/3689/5721/3601/5724/5034 415 Epstein.Barr_virus R-HSA-5663205 Infectious disease 352/5894 383/10654 4.494251529546477e-58 3.1617059510359467e-55 1.1448514422634183e-55 3839/6158/6884/23165/6875/5689/51652/6138/2237/6227/7852/6206/6234/6191/162/6128/5682/6132/6129/4057/27243/6874/6176/1174/811/6224/6146/348995/6154/143471/6202/57122/5705/55048/3981/6169/5431/23511/5435/5709/9978/6175/5433/6218/5695/2960/292/567/51271/6173/23279/5605/6167/5711/23327/116832/29082/23225/5683/2965/2534/6156/27183/5699/6143/5439/5702/6456/6873/3836/6139/30011/2885/163/9972/6881/2967/51616/3921/8021/7040/1794/11198/904/51497/5062/55746/6208/5696/6170/5691/92421/7296/7314/5879/5718/137492/3303/8945/6203/1839/161/402569/6171/5606/6147/25978/5700/51160/122706/5707/2959/8027/10053/6222/2060/7518/8106/23198/404672/9636/10015/91782/5438/6134/3978/10762/79720/6155/1500/51534/4836/926/9397/6714/6231/9861/79902/6142/11168/9883/23521/89853/83860/51510/999/5698/9146/6455/5692/5713/5710/2068/5902/6207/5478/5719/6233/6844/7514/1025/3932/1213/5610/1211/6188/6396/129401/6883/7936/1175/6829/801/5608/8907/200916/6122/2957/940/805/25920/6230/60489/928/1173/4928/2963/3838/5434/5903/6857/6194/55706/7175/79643/6166/1938/5436/6136/6878/6125/4869/821/5706/6232/160/6160/6616/293/5611/920/4233/4331/5714/6193/4927/6210/6229/8148/6205/2966/2962/10898/3840/5688/54457/8812/5687/5708/128866/140801/6235/905/6181/2071/5901/8086/5704/3326/7311/6223/25873/93343/6880/6908/7251/8905/5694/3304/1104/2547/9045/6882/2961/6187/6416/5432/6168/22916/155382/1234/6157/6137/6877/5905/6144/3837/6917/81929/5440/164/5684/9349/8065/4736/5720/902/79872/51121/9631/5604/1499/3159/6159/6217/3843/5430/6152/5690/5045/7520/5717/9491/6500/6749/51065/6141/79023/6123/5441/23636/10197/919/130340/6164/4686/7316/10213/6872/53371/3055/6209/9688/11224/6165/8731/6130/6879/5715/9525/6204/5701/2958/867/6228/5437/5685/3320/8815/5686/6124/5609/2968/5716/9844/2984/6189/808/6135/6201/375/6161/138474/1022/5693/10254/5721/6457/8178/8480/6133/291 352 Epstein.Barr_virus R-HSA-5663202 Diseases of signal transduction 346/5894 377/10654 1.0940476381333743e-56 5.1310834228455256e-54 1.8579616030054497e-54 5295/8454/2308/27123/5689/374/4893/11052/2250/5335/71/79718/5682/5291/892/5526/817/1452/9530/613/9372/182/5908/3082/941/55109/143471/23385/2064/5705/54845/5431/6776/5435/5709/9978/5433/5695/8546/9759/9612/22866/5605/4609/4089/22938/5037/3549/5711/1387/3717/10827/4088/2244/6907/5683/145957/324/2534/3690/408/9965/5699/6400/8312/11064/5439/2264/5702/4296/5894/6868/9794/9542/2885/2475/8660/8826/9846/5518/57534/2252/6469/1185/4140/7040/2253/3845/388585/3265/80351/4763/5696/7750/5691/28514/7314/5879/5515/5718/818/8805/1839/26127/5290/3667/6801/8823/79885/2065/2648/9734/55869/55750/5700/3815/122706/5707/10956/8844/51564/7094/8322/55534/5594/3280/2069/84335/8074/7249/23198/84441/7414/10533/10013/23164/2260/5438/5528/83933/3714/89780/102/8323/57085/2249/6714/2099/50846/5664/9861/2248/5519/9061/8850/399687/2932/7046/2247/5698/5880/10000/5692/5713/2335/1445/5710/3066/2280/5719/6233/2266/7409/2246/2251/3932/2931/2243/7855/118788/6777/369/801/5781/5663/940/1523/57670/253260/805/5170/2963/5434/7276/6464/142678/572/283455/3674/5436/4303/409/930/5706/6199/10046/9208/84447/673/8315/6774/2263/4233/8658/1024/5714/6772/6934/64223/10014/2962/8503/5688/5159/5687/29851/5708/3084/26508/9148/5529/816/4087/208/6654/5704/83464/10718/79109/56829/7048/23493/7311/5293/7450/1956/11160/60/9444/55851/2549/51107/611/5694/4851/5432/22916/11140/7529/5595/5516/4000/1147/27044/815/5440/5684/22906/8841/685/5720/8087/1487/2309/5604/1499/6017/10018/5525/10142/842/139285/5430/23462/207/5690/5717/1027/9491/6500/8817/5441/10197/54518/2100/2254/4686/7316/10213/152831/1950/9611/54492/1026/50852/26281/10818/7415/5715/80853/10256/2261/5701/867/5437/5685/2255/3164/3320/5686/2033/54894/391/55294/5728/3065/2066/27006/942/5527/1488/5716/1385/5906/5155/54567/4254/5296/808/3516/9715/5693/5721/5245/5156/4193 346 Epstein.Barr_virus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 237/5894 244/10654 5.387880759723305e-52 1.8951870572326726e-49 6.862458651858104e-50 8449/23165/6633/8683/6431/84271/55696/4904/51639/51585/9128/199746/23450/348995/57122/5431/9092/23511/81608/5435/6625/5433/51645/3190/1477/9416/65109/56339/22826/23279/8233/22938/988/23020/23225/6631/3181/5439/1660/9410/6638/57721/9877/9972/8021/3312/10907/10291/55746/26121/10262/7919/53981/6432/10084/8563/6430/51340/6627/6936/83443/11051/80145/9129/9879/10081/8106/51690/27238/55749/5438/85313/10762/54883/22794/9785/11338/1655/9343/29107/3185/4116/6626/11157/285755/1478/24144/79902/9883/51213/10236/10250/4670/26097/8926/51362/10465/55660/25949/23283/2521/1977/3191/10285/6636/23524/10914/57187/6396/129401/79228/8175/2733/84950/3188/84324/56259/5725/1994/10450/7536/4928/2963/6635/5434/5903/220988/6632/10283/55706/7175/24148/154007/100534599/7884/23350/5436/10523/6428/27258/10212/6637/55110/5093/55954/84321/6429/57819/4927/10181/2962/10898/10569/23658/6434/9295/84844/10482/51692/10421/11193/8086/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/81929/5440/55599/51691/10946/9631/27339/5430/79869/85437/11325/57703/3184/25804/29894/9589/11017/51503/3178/79023/5441/23636/3183/79622/10594/4686/8189/23398/10713/53371/10978/5546/7307/10772/9688/9984/5437/6629/10189/10949/51729/11066/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/84248/6427/5356/57461/84991/8480/10992/55339/6628 237 Epstein.Barr_virus R-HSA-9006925 Intracellular signaling by second messengers 281/5894 305/10654 5.839079087509378e-47 1.6431168552251387e-44 5.949714270220082e-45 5295/1912/2308/5689/374/3725/6591/3643/2250/5335/5682/23035/5291/1822/1459/5526/9112/817/6045/5578/5582/27327/80012/3082/1460/941/143471/2064/5705/5709/5695/107/1457/1911/4734/11060/5711/5928/5683/145957/2534/23512/9965/57332/5699/2444/2264/3630/5702/192669/1107/8975/3654/5371/9542/2885/8396/2475/51135/8660/5518/1386/2252/4343/2253/80351/5696/814/5691/7314/5879/5515/5718/818/23396/1839/5290/3667/6801/8823/90865/2065/23186/5700/3815/122706/5707/5567/2146/51564/5594/2069/84335/84232/8074/7249/23198/79837/112/57761/2260/5573/5528/111/2249/6714/2099/9861/7101/81847/2248/5519/2932/84733/57459/2247/5698/5880/10000/5692/5713/5710/3066/7157/5613/5719/6233/5580/7409/2246/2251/3932/2931/118788/331/8726/5153/196883/8394/115/26523/7874/801/5781/57521/23608/940/6015/253260/28956/805/5170/3838/572/23239/389541/9219/8535/4303/5568/930/5931/5706/6199/113/2263/4233/8658/5714/10645/1108/2122/64223/5566/84254/10014/8503/5688/5159/5687/29851/5708/3084/54815/6009/5529/816/7189/208/5577/5704/10718/79109/55004/57504/7311/5293/1956/648/2549/5694/23466/53615/109/5595/3556/5516/1147/27161/815/5684/8841/685/5305/5720/2309/5468/5525/5575/842/5978/8870/10273/207/5690/57690/5717/1027/9491/8817/114/10197/108/192670/4615/2100/2254/7316/10213/152831/1950/1026/50852/10768/26281/57167/10818/5715/1958/2261/5701/5576/5685/2255/8649/3164/5686/391/5728/6615/3065/2066/27006/23028/942/5987/23112/10542/5527/5716/1385/9173/5155/4254/5296/5581/808/5693/5721/5156/4193 281 Epstein.Barr_virus R-HSA-3700989 Transcriptional Regulation by TP53 325/5894 365/10654 6.9959317447649084e-46 1.640545994147371e-43 5.940405200817921e-44 6884/6875/834/5563/3725/9134/4436/83990/64769/5892/9156/57060/1763/7531/1459/79370/7486/6874/10971/9997/133383/9212/5982/27327/7295/7533/2810/55367/1460/11200/472/53632/79813/5431/7001/639/5435/5433/1869/28996/84289/1457/6790/25904/29117/4194/1647/5928/1432/1387/4683/56950/51499/2965/84126/8738/5439/192669/1107/8900/6873/5371/8396/2475/672/55571/6881/2967/51616/5518/1386/55835/4513/4343/6117/11198/7159/57472/904/144455/85456/29883/51497/51230/637/83695/7296/7314/5515/1263/27166/23368/9377/23774/6118/2176/1329/3622/7027/6446/2936/7832/51422/7249/404672/79837/898/117584/27244/7534/332/5438/5934/64065/116028/890/10769/983/1643/8797/9656/5519/27154/5458/83860/57459/2821/2177/10000/5985/2877/900/7994/2068/54541/3066/7157/5984/6233/1121/1025/2353/604/63970/839/7029/10419/5325/50484/5600/6883/7936/6829/79733/26523/7874/317/2744/5608/5884/5810/57521/26155/26013/5875/253260/28956/25920/5170/80010/2963/5434/83667/1820/7862/1029/389541/5457/9219/8445/7532/5436/55240/204851/6878/4869/5931/4850/4292/580/11073/891/80196/54971/4331/5366/641/5111/1108/8148/2966/246175/64223/2962/84883/6119/147923/3364/5571/10524/54457/4848/8812/144715/23019/1616/843/6794/54815/94241/1874/10128/25824/6009/905/1111/2071/55215/8626/208/79109/55004/7311/7161/5562/6880/6908/5983/4697/5564/6882/5565/1020/53615/10397/8795/5432/665/7248/6877/7529/5516/1017/27161/27113/9891/6917/5440/27165/5305/8621/902/5883/25946/9540/5430/10111/8793/207/22974/57690/835/4849/1027/58484/3486/355/6749/545/5441/8794/192670/8550/9337/7316/6872/2539/1026/54205/5933/124446/5395/6879/112858/5876/143686/10848/5437/9099/8649/28984/51755/2033/995/5728/3065/91875/23112/10498/10542/5527/2968/5932/8851/5300/7156/581/3276/5052/138474/133746/1022/8178/10919/4193 325 Epstein.Barr_virus R-HSA-72172 mRNA Splicing 188/5894 191/10654 1.306297839188934e-44 2.6256586567697572e-42 9.507491040111939e-43 8449/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/5431/9092/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/8233/22938/988/23020/6631/3181/5439/1660/9410/6638/3312/10907/10291/26121/10262/53981/6432/10084/6430/51340/6627/6936/83443/11051/9129/9879/10081/8106/51690/27238/55749/5438/85313/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/10236/10250/4670/8926/51362/10465/55660/25949/23283/2521/3191/10285/6636/23524/10914/8175/84950/3188/56259/5725/1994/10450/7536/2963/6635/5434/220988/6632/10283/24148/154007/100534599/23350/5436/10523/6428/27258/6637/55110/5093/55954/6429/57819/10181/2962/10898/10569/23658/6434/9295/84844/51692/10421/11193/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/55599/51691/10946/27339/5430/79869/85437/11325/57703/3184/25804/29894/11017/51503/3178/5441/3183/79622/10594/4686/8189/23398/10713/10978/5546/7307/10772/5437/6629/10189/10949/51729/11066/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/57461/84991/10992/55339/6628 188 Epstein.Barr_virus R-HSA-1257604 PIP3 activates AKT signaling 246/5894 264/10654 1.5127433811285134e-43 2.6605374215597727e-41 9.6337867956079e-42 5295/1912/2308/5689/374/3725/6591/3643/2250/5682/23035/5291/1822/1459/5526/9112/6045/27327/80012/3082/1460/941/143471/2064/5705/5709/5695/1457/1911/4734/11060/5711/5928/5683/145957/2534/23512/9965/57332/5699/2444/2264/3630/5702/192669/1107/8975/3654/5371/9542/2885/8396/2475/51135/8660/5518/1386/2252/4343/2253/80351/5696/5691/7314/5879/5515/5718/23396/1839/5290/3667/6801/8823/90865/2065/23186/5700/3815/122706/5707/2146/51564/5594/2069/84335/84232/8074/7249/23198/79837/57761/2260/5528/2249/6714/2099/9861/7101/81847/2248/5519/2932/84733/57459/2247/5698/5880/10000/5692/5713/5710/3066/7157/5719/6233/7409/2246/2251/3932/2931/118788/331/8726/8394/26523/7874/5781/57521/23608/940/6015/253260/28956/5170/572/23239/389541/9219/8535/4303/930/5931/5706/6199/2263/4233/8658/5714/1108/2122/64223/10014/8503/5688/5159/5687/29851/5708/3084/54815/6009/5529/7189/208/5704/10718/79109/55004/57504/7311/5293/1956/648/2549/5694/23466/53615/5595/3556/5516/1147/27161/5684/8841/685/5305/5720/2309/5468/5525/842/5978/8870/10273/207/5690/57690/5717/1027/9491/8817/10197/192670/4615/2100/2254/7316/10213/152831/1950/1026/50852/26281/57167/10818/5715/1958/2261/5701/5685/2255/8649/3164/5686/391/5728/6615/3065/2066/27006/23028/942/5987/23112/10542/5527/5716/1385/9173/5155/4254/5296/5693/5721/5156/4193 246 Epstein.Barr_virus R-HSA-72163 mRNA Splicing - Major Pathway 180/5894 183/10654 1.4646207164678397e-42 2.2896903867447227e-40 8.290952359888121e-41 8449/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/5431/9092/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/22938/988/23020/6631/3181/5439/1660/9410/6638/3312/10907/10291/26121/10262/53981/6432/10084/6430/51340/6627/6936/83443/11051/9129/9879/8106/51690/27238/55749/5438/85313/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/10236/10250/4670/8926/51362/10465/55660/25949/23283/2521/3191/10285/6636/23524/10914/8175/84950/3188/56259/5725/1994/10450/7536/2963/6635/5434/220988/6632/10283/24148/100534599/23350/5436/10523/6428/27258/6637/55110/5093/6429/57819/10181/2962/10898/10569/23658/6434/9295/84844/51692/10421/11193/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/51691/10946/27339/5430/79869/11325/57703/3184/25804/29894/11017/51503/3178/5441/3183/10594/4686/8189/23398/10713/10978/5546/7307/10772/5437/6629/10189/10949/51729/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/57461/84991/10992/55339/6628 180 Epstein.Barr_virus R-HSA-913531 Interferon Signaling 192/5894 199/10654 9.76357583639242e-41 1.3737351201804135e-38 4.974284952435717e-39 80263/3839/3443/23165/5777/3442/5335/960/5770/3107/817/9021/348995/317649/3383/57122/11274/55223/3662/3115/23511/4684/567/4734/6672/3113/23279/3106/8672/3459/3717/23225/3117/1973/11074/3836/5371/4599/684/9972/3133/3429/117854/8021/3127/91543/7334/4938/4261/55746/5696/7314/3445/818/402569/115362/7412/10410/85363/9830/163351/9636/3126/2634/3444/10762/2317/115361/103/3434/10475/3433/79902/23586/9883/3451/10437/3448/1981/10612/3458/3661/7324/1977/3439/51191/6233/5580/81603/10107/5610/10581/3452/4940/6396/3437/129401/6773/7297/5781/3430/3660/3446/8554/3135/3665/3120/4928/3838/5903/10379/55706/7175/3455/2316/2633/4600/3123/23650/2209/8638/25820/1982/7706/23087/9470/3122/3394/3663/6772/8651/4927/3659/3840/25939/2635/3440/5771/3454/816/8086/10346/9246/3716/7311/7318/3125/7726/79097/3456/53840/3105/1974/5595/3460/815/3837/81929/3441/6737/51447/9631/23321/4281/3119/4502/54739/79023/2537/23636/3449/51127/7316/53371/8519/3664/9688/6041/1958/4939/388646/7341/6059/55128/3669/3134/5300/9775/80128/5495/5724/8480 192 Epstein.Barr_virus R-HSA-5683057 MAPK family signaling cascades 264/5894 294/10654 6.124019829056842e-39 7.83317809043907e-37 2.836388131352643e-37 2308/5689/374/2118/3725/2674/4893/6711/2250/1437/71/5682/1844/1850/1848/5526/817/84292/27327/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/22866/5605/4609/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/192669/4296/5894/1847/3563/9542/1739/2885/6709/8660/8997/8826/5518/2252/4140/4343/2253/3845/5623/3265/4763/3569/5062/5696/5691/7314/3572/5879/5515/5923/5718/818/57554/1839/3667/8823/2065/5700/3815/122706/5707/5567/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/3337/4902/2260/5528/2902/983/3718/2249/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/80824/1445/5710/8555/896/5719/6233/2266/2246/7514/2251/2243/1843/3570/26523/369/801/200734/7297/5781/8682/4747/10602/1846/11221/28956/805/22821/9462/3562/6464/6712/2904/5747/283455/3674/7010/5568/2322/2675/3315/409/5706/1438/673/2676/8315/2263/4233/5597/84078/5714/5566/6710/5688/5159/5687/5708/3084/5063/5529/816/998/9693/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/5058/7529/5595/25759/5516/27161/815/5684/685/5720/2309/5604/3561/5525/153090/10642/10048/5690/57690/5717/9491/3568/8817/10197/192670/5596/8550/54518/2254/7316/10213/152831/1950/3560/26281/10818/5715/8437/10256/2261/5701/27040/5685/2255/8649/5686/2066/27006/8556/5979/23112/1742/5527/5716/88/5906/5155/9048/4254/5896/399473/808/3559/8202/5693/5721/5245/5156/161742/284 264 Epstein.Barr_virus R-HSA-162906 HIV Infection 216/5894 233/10654 2.2879648938588385e-37 2.682638838049488e-35 9.713815865155068e-36 6884/23165/6875/5689/51652/2237/7852/162/5682/27243/6874/1174/348995/143471/57122/5705/55048/3981/5431/23511/5435/5709/9978/5433/5695/2960/292/567/51271/23279/5711/23327/29082/23225/5683/2965/2534/27183/5699/5439/5702/6873/3836/163/9972/6881/2967/51616/8021/1794/11198/904/51497/5062/55746/5696/5691/92421/7314/5879/5718/137492/8945/161/25978/5700/51160/122706/5707/2959/10053/7518/23198/404672/10015/91782/5438/3978/10762/79720/51534/4836/926/9397/9861/79902/11168/9883/89853/83860/51510/5698/5692/5713/5710/2068/5902/5478/5719/6233/7514/1025/3932/6396/129401/6883/7936/1175/6829/8907/2957/940/25920/60489/1173/4928/2963/5434/5903/55706/7175/79643/5436/6878/4869/5706/160/293/920/4331/5714/4927/8148/2966/2962/5688/54457/8812/5687/5708/128866/905/2071/5901/8086/5704/7311/93343/6880/6908/7251/8905/5694/1104/2547/6882/2961/5432/22916/155382/1234/6877/5905/3837/6917/81929/5440/164/5684/8065/5720/902/9631/3159/5430/5690/5045/7520/5717/9491/6500/6749/79023/5441/23636/10197/919/130340/4686/7316/10213/6872/53371/3055/9688/8731/6879/5715/9525/5701/2958/5437/5685/8815/5686/2968/5716/9844/375/138474/1022/5693/5721/8178/8480/291 216 Epstein.Barr_virus R-HSA-2555396 Mitotic Metaphase and Anaphase 191/5894 202/10654 1.5441019327607818e-36 1.671193399534169e-34 6.051379234463307e-35 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/5520/81027/51529/4001/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/221496/7444/5698/5692/5713/91687/119504/11243/10376/5710/7324/83540/2010/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/26271/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/347733/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/7443/23141/1781/7316/10213/4085/55166/5715/5701/5685/8815/5686/79003/9126/9232/23592/9700/5527/5716/701/57551/5693/5721 191 Epstein.Barr_virus R-HSA-68882 Mitotic Anaphase 190/5894 201/10654 2.6766427010457732e-36 2.690025914551002e-34 9.740564415835745e-35 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/5520/81027/51529/4001/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/221496/7444/5698/5692/5713/91687/119504/11243/10376/5710/7324/83540/2010/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/347733/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/7443/23141/1781/7316/10213/4085/55166/5715/5701/5685/8815/5686/79003/9126/9232/23592/9700/5527/5716/701/57551/5693/5721 190 Epstein.Barr_virus R-HSA-69242 S Phase 157/5894 161/10654 1.977583638382646e-35 1.854973452802922e-33 6.716845480541759e-34 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/10274/5925/143471/5705/5709/5422/9978/1869/4174/5753/5695/84515/4609/4998/5711/5928/5683/990/5699/5702/8900/51529/29945/51434/84296/157570/6117/29882/5001/10714/7465/5558/5696/5691/7314/996/5718/6118/23594/7027/5700/122706/5707/64785/23198/898/3978/91768/5934/5557/993/890/51433/9861/2932/6502/5698/10000/5692/5985/5713/119504/595/4175/5710/5984/7324/5719/64682/6233/7029/113130/23649/1163/5424/4999/4172/1019/5000/8318/246184/54107/4173/5706/286826/23047/8881/5885/4331/5425/5714/5111/6119/5688/5687/5427/5708/1874/8243/81620/10393/208/5704/55957/51343/23595/7311/25906/51659/5983/5694/4176/56655/1017/5684/994/5720/902/57804/207/9837/5690/5717/1027/9491/6500/23244/10735/10197/4149/7316/10213/1875/1026/5426/4171/5715/5701/5685/5686/9126/5716/114799/5981/1022/5693/5721 157 Epstein.Barr_virus R-HSA-5633007 Regulation of TP53 Activity 156/5894 160/10654 3.527582789732393e-35 3.102068115720923e-33 1.1232566251516303e-33 6884/6875/5563/83990/64769/9156/1763/1459/7486/6874/133383/9212/5982/1460/11200/472/53632/79813/639/28996/84289/1457/6790/29117/4194/5928/1432/4683/56950/84126/1107/8900/6873/5371/8396/2475/672/6881/51616/5518/6117/11198/7159/51230/83695/7314/5515/1263/23368/23774/6118/3622/6446/51422/79837/117584/116028/890/983/5519/27154/5458/83860/57459/10000/5985/900/7994/3066/7157/5984/6233/10419/5600/6883/7874/5608/5884/5810/26155/26013/253260/5170/80010/7862/1029/5457/9219/8445/204851/6878/5931/580/11073/80196/54971/641/1108/8148/64223/6119/3364/5571/10524/54457/144715/1616/6794/54815/94241/1111/8626/208/79109/7311/7161/5562/6880/6908/5983/5564/6882/5565/1020/53615/6877/5516/1017/9891/5305/5883/25946/10111/207/22974/6749/545/8550/7316/6872/6879/112858/10848/9099/2033/3065/91875/5527/5932/8851/5300/7156/138474/133746/10919/4193 156 Epstein.Barr_virus R-HSA-68877 Mitotic Prometaphase 188/5894 200/10654 6.123968516073213e-35 5.0684845306558885e-33 1.8352945893371115e-33 114791/10844/55839/11130/440145/6249/9735/7531/1459/11190/203068/5526/54801/51807/9212/347688/10274/1460/147841/348995/79441/10381/57122/5116/1780/23122/5048/57405/8655/1457/23279/9702/2491/7846/7840/1060/11064/81027/11004/9184/5518/55835/29922/23332/25909/10726/81930/55746/93323/5515/79682/10403/79861/64151/25936/55869/1454/3619/64105/332/10051/5528/983/79902/3796/79959/5519/81565/80097/91687/11243/10376/23397/10540/85378/83540/7514/54930/54820/113130/6396/1453/27229/64946/9793/140735/220134/84617/4928/5903/11258/22981/55055/8636/80776/1783/401541/7532/55125/10382/79172/121441/7277/9133/79980/6232/23047/9814/653784/5885/23354/891/5501/9738/1639/55722/4957/5566/54821/9183/1062/699/7283/347733/22919/8243/10426/5529/22994/51143/1069/5577/10383/5347/84790/84643/80184/22897/5108/10592/7280/10806/1778/5516/115106/4926/5905/22995/55559/81929/54908/55143/5525/10142/1058/991/79019/348235/80152/1063/8379/95681/23244/23421/55920/79023/10735/1781/80321/4085/55166/10121/84131/3320/79003/9126/9918/10733/4751/5527/27175/80254/701/57551/9662/55142/8481/55755 188 Epstein.Barr_virus R-HSA-9607240 FLT3 Signaling 239/5894 267/10654 8.742860138185828e-35 6.83400234134859e-33 2.4745873139660468e-33 5295/5689/374/2674/4893/6711/2250/1437/71/5682/1844/5291/1850/1848/5526/817/84292/5908/3082/143471/2064/5705/8452/6776/4684/5709/9978/5695/1852/2668/22866/5605/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/1847/3563/9542/1739/2885/6709/8660/8826/9846/5518/2252/4140/2253/3845/5623/3265/4763/5696/5691/7314/5515/54106/5923/5718/818/57554/1839/5290/3667/8823/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/57761/5921/4902/2260/5528/2902/3718/2249/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/80824/1445/5710/5719/6233/2266/2246/2251/2243/1843/6777/369/801/200734/5781/30849/8682/4747/1846/11221/28956/805/22821/5170/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/409/5706/1438/673/2676/8315/2263/4233/84078/5714/6710/5688/5159/5687/5708/3084/5529/816/9693/208/6654/5704/10718/3716/7311/7450/1956/60/5536/2549/5694/7529/5595/25759/5516/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10197/54518/2254/7316/10213/152831/1950/3560/5289/3055/26281/10818/5715/8437/10256/2261/5701/27040/5685/2255/8649/5686/2066/27006/5979/1742/5527/5716/88/5906/5155/9048/4254/5296/399473/808/3559/5693/5721/5245/5156/161742/284 239 Epstein.Barr_virus R-HSA-453274 Mitotic G2-G2/M phases 186/5894 198/10654 1.8169262388069229e-34 1.345481693684916e-32 4.871979499072302e-33 114791/10844/8454/5689/440145/5682/7531/11190/203068/54801/51807/63943/347688/51400/79441/143471/10381/5705/5116/5048/5709/9978/1869/5695/8655/6790/9702/5711/5928/7846/7840/5683/5699/11064/5702/5520/81027/8900/5518/55835/29922/23332/7465/93323/5696/5691/7314/5515/5718/8945/79861/4659/5700/122706/5707/1454/23198/993/890/983/9861/79959/5519/5698/5692/5713/80097/10376/5710/10540/7157/85378/5719/6233/7514/54930/54820/1453/27229/9793/4218/5500/84617/2305/11258/22981/8636/51512/7532/84962/55125/10382/121441/7277/5706/9133/286826/9814/653784/23354/728642/891/9738/4331/1639/5714/55722/4957/5566/5688/5687/7283/347733/5708/22919/984/10426/22994/79866/1069/5577/5704/3326/55957/7311/10133/10383/5347/84790/80184/5694/22897/5108/7280/10806/1778/5516/115106/1017/22995/55559/5684/994/5720/4605/902/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/1781/7316/10213/80321/1026/10121/1871/5715/84131/9088/5701/23291/5685/3320/5686/2033/995/10733/4751/27175/80254/5716/23194/9662/55142/1022/8481/5693/5721/55755 186 Epstein.Barr_virus R-HSA-69275 G2/M Transition 184/5894 196/10654 5.382066436936139e-34 3.7862837383845736e-32 1.3710106081458375e-32 114791/10844/8454/5689/440145/5682/7531/11190/203068/54801/51807/63943/347688/51400/79441/143471/10381/5705/5116/5048/5709/9978/5695/8655/6790/9702/5711/5928/7846/7840/5683/5699/11064/5702/5520/81027/8900/5518/55835/29922/23332/7465/93323/5696/5691/7314/5515/5718/8945/79861/4659/5700/122706/5707/1454/23198/993/890/983/9861/79959/5519/5698/5692/5713/80097/10376/5710/10540/7157/85378/5719/6233/7514/54930/54820/1453/27229/9793/4218/5500/84617/2305/11258/22981/8636/51512/7532/84962/55125/10382/121441/7277/5706/9133/286826/9814/653784/23354/728642/891/9738/4331/1639/5714/55722/4957/5566/5688/5687/7283/347733/5708/22919/984/10426/22994/79866/1069/5577/5704/3326/55957/7311/10133/10383/5347/84790/80184/5694/22897/5108/7280/10806/1778/5516/115106/1017/22995/55559/5684/994/5720/4605/902/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/1781/7316/10213/80321/1026/10121/5715/84131/9088/5701/23291/5685/3320/5686/2033/995/10733/4751/27175/80254/5716/23194/9662/55142/1022/8481/5693/5721/55755 184 Epstein.Barr_virus R-HSA-5684996 MAPK1/MAPK3 signaling 229/5894 255/10654 6.795377401251351e-34 4.552902858838405e-32 1.6486028381983225e-32 5689/374/2674/4893/6711/2250/1437/71/5682/1844/1850/1848/5526/817/84292/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/22866/5605/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/1847/3563/9542/1739/2885/6709/8660/8826/5518/2252/4140/2253/3845/5623/3265/4763/3569/5696/5691/7314/3572/5515/5923/5718/818/57554/1839/3667/8823/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/4902/2260/5528/2902/983/3718/2249/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/80824/1445/5710/5719/6233/2266/2246/2251/2243/1843/3570/369/801/200734/7297/5781/8682/4747/1846/11221/28956/805/22821/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/409/5706/1438/673/2676/8315/2263/4233/84078/5714/6710/5688/5159/5687/5708/3084/5529/816/9693/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/7529/5595/25759/5516/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10197/54518/2254/7316/10213/152831/1950/3560/26281/10818/5715/8437/10256/2261/5701/27040/5685/2255/8649/5686/2066/27006/5979/1742/5527/5716/88/5906/5155/9048/4254/399473/808/3559/5693/5721/5245/5156/161742/284 229 Epstein.Barr_virus R-HSA-2467813 Separation of Sister Chromatids 179/5894 190/10654 1.1091540466041925e-33 7.093544288964085e-32 2.568567265820235e-32 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/81027/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/5698/5692/5713/91687/119504/11243/10376/5710/7324/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/347733/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7280/1778/5516/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/1781/7316/10213/4085/55166/5715/5701/5685/5686/79003/9126/9232/9700/5527/5716/701/57551/5693/5721 179 Epstein.Barr_virus R-HSA-5673001 RAF/MAP kinase cascade 223/5894 249/10654 1.3580773755386896e-32 8.307890727751897e-31 3.008281234602864e-31 5689/374/2674/4893/6711/2250/1437/71/5682/1844/1850/1848/5526/817/84292/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/22866/5605/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/1847/3563/9542/1739/2885/6709/8660/8826/5518/2252/4140/2253/3845/5623/3265/4763/5696/5691/7314/5515/5923/5718/818/57554/1839/3667/8823/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/4902/2260/5528/2902/3718/2249/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/80824/1445/5710/5719/6233/2266/2246/2251/2243/1843/369/801/200734/8682/4747/1846/11221/28956/805/22821/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/409/5706/1438/673/2676/8315/2263/4233/84078/5714/6710/5688/5159/5687/5708/3084/5529/816/9693/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/7529/5595/25759/5516/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10197/54518/2254/7316/10213/152831/1950/3560/26281/10818/5715/8437/10256/2261/5701/27040/5685/2255/8649/5686/2066/27006/5979/1742/5527/5716/88/5906/5155/9048/4254/399473/808/3559/5693/5721/5245/5156/161742/284 223 Epstein.Barr_virus R-HSA-453279 Mitotic G1-G1/S phases 145/5894 149/10654 2.019735584848068e-32 1.1840699866171799e-30 4.28750887309853e-31 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/1031/4998/5711/5928/10926/3717/5683/990/5699/5702/5520/8900/55388/1032/1030/5518/6117/5001/7465/5558/5696/5691/7314/5515/6241/5718/6118/25/23594/7027/5700/5707/7153/898/91768/5934/5557/993/890/1876/983/6714/9861/5519/6502/5698/10000/5692/5713/595/4175/5710/896/5719/6233/7298/7029/23649/1719/1163/1859/4999/4172/26271/1019/5000/8318/1029/54107/4173/5706/286826/891/4331/5714/5111/51053/6119/5688/5687/5427/4067/5708/1874/81620/208/1870/5704/29935/55957/23595/7311/5694/4176/5516/56655/1017/894/5684/5720/4605/902/8317/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5933/5426/4171/1871/5715/5701/5685/5686/1021/3065/5716/1022/5693/5721/7083/1028 145 Epstein.Barr_virus R-HSA-69306 DNA Replication 126/5894 127/10654 1.2767950317045544e-31 7.185802438433232e-30 2.6019738751368598e-30 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/143471/5705/5709/5422/9978/1869/4174/5695/84515/4998/5711/10926/5683/990/5699/5702/8900/51529/29945/51434/55388/84296/6117/29882/5001/10714/5558/5696/5691/7314/996/5718/6118/23594/5700/122706/5707/64785/23198/898/3978/5557/890/51433/9861/6502/5698/5692/5985/5713/119504/4175/5710/5984/7324/5719/64682/6233/23649/5424/4999/4172/5000/8318/246184/54107/4173/5706/8881/5425/5714/5111/51053/6119/5688/5687/5427/5708/81620/10393/1870/5704/29935/51343/23595/7311/25906/51659/5983/5694/4176/56655/1017/5684/5720/57804/8317/9837/5690/5717/9491/6500/10197/7316/10213/5426/4171/1871/5715/5701/5685/5686/5716/5981/5693/5721 126 Epstein.Barr_virus R-HSA-168254 Influenza Infection 149/5894 155/10654 3.3411083963037683e-31 1.808053659076693e-29 6.546949246198477e-30 3839/6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/116832/23225/6156/6143/5439/3836/6139/9972/3921/8021/7040/55746/6208/6170/3303/6203/402569/6171/6147/6222/8106/9636/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/7514/1213/5610/1211/6188/6396/129401/200916/6122/6230/4928/2963/3838/5434/5903/6194/55706/7175/6166/5436/6136/6125/821/6232/6160/293/5611/6193/4927/6210/6229/6205/2962/10898/3840/140801/6235/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/81929/5440/9349/4736/51121/9631/6159/6217/3843/5430/6152/51065/6141/79023/6123/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 149 Epstein.Barr_virus R-HSA-168255 Influenza Life Cycle 139/5894 144/10654 8.370561716154e-30 4.3619927165291405e-28 1.579474413496505e-28 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/116832/23225/6156/6143/5439/3836/6139/9972/3921/8021/55746/6208/6170/3303/6203/6171/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/7514/1213/1211/6188/6396/129401/200916/6122/6230/4928/2963/5434/5903/6194/55706/7175/6166/5436/6136/6125/821/6232/6160/5611/6193/4927/6210/6229/6205/2962/140801/6235/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/81929/5440/9349/4736/51121/9631/6159/6217/3843/5430/6152/51065/6141/79023/6123/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 139 Epstein.Barr_virus R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 118/5894 119/10654 1.4694569461420847e-29 7.129399735247976e-28 2.5815504970336444e-28 5244/84498/79718/9441/34/892/27063/1543/54600/5469/9612/27242/11010/1387/6907/2101/84246/26230/4801/29841/50486/2274/1376/55588/10499/23054/9575/1581/9572/85441/9282/23097/10062/7296/96764/51129/57761/5465/9915/2222/10025/3157/6667/23309/336/3156/6604/80205/9439/3992/4199/123/2168/183/116519/6257/3158/376497/9412/9969/405/133522/54797/55090/4899/1374/9440/6721/51/9862/23179/9442/406/19/335/4800/1024/9968/10001/23389/9971/9443/211/9477/1579/25942/51586/400569/6095/6822/80306/8841/5468/29079/4802/4862/90390/6720/6837/9611/2874/81857/2033/8800/9967/6256/51003/7376/10498/948/112950/196/4520/8202/8648/2180/10891/219541 118 Epstein.Barr_virus R-HSA-69239 Synthesis of DNA 118/5894 119/10654 1.4694569461420847e-29 7.129399735247976e-28 2.5815504970336444e-28 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/143471/5705/5709/5422/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/84296/6117/29882/5001/10714/5558/5696/5691/7314/996/5718/6118/23594/5700/122706/5707/64785/23198/898/3978/5557/890/51433/9861/6502/5698/5692/5985/5713/119504/4175/5710/5984/7324/5719/64682/6233/23649/5424/4999/4172/5000/8318/246184/54107/4173/5706/8881/5425/5714/5111/6119/5688/5687/5427/5708/81620/10393/5704/51343/23595/7311/25906/51659/5983/5694/4176/56655/1017/5684/5720/57804/9837/5690/5717/9491/6500/10197/7316/10213/5426/4171/5715/5701/5685/5686/5716/5981/5693/5721 118 Epstein.Barr_virus R-HSA-5696398 Nucleotide Excision Repair 111/5894 111/10654 1.8141039351136866e-29 8.50814745568319e-28 3.0807940512106115e-028 2074/10445/5982/6613/7507/5431/5435/9978/5433/85015/10980/57654/2965/5439/10987/2067/2967/6612/6117/7334/10714/91603/7314/6118/83444/404672/9557/3150/86/5438/3978/1643/29844/5985/10920/2068/5984/54891/6233/93973/8607/7874/5424/5886/8451/8554/10450/5434/100534599/5436/7515/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/142/125476/2071/1069/7329/51426/2873/7311/3980/60/8533/5983/10038/5432/51138/7528/56655/9318/6917/5440/902/27339/5430/57804/5441/7336/2072/54778/7316/64708/5426/283899/7341/4798/5437/79913/10401/54617/2033/2968/56949/5887/9716/2073/5981/57461/1022/8178/50813/7508 111 Epstein.Barr_virus R-HSA-1989781 PPARA activates gene expression 116/5894 117/10654 4.8060145079398567e-29 2.1813104557004446e-27 7.898509412030188e-28 5244/84498/79718/9441/34/892/27063/1543/54600/5469/9612/27242/11010/1387/6907/2101/84246/26230/4801/29841/50486/2274/1376/55588/10499/23054/9575/1581/9572/85441/9282/23097/10062/7296/96764/51129/57761/5465/9915/2222/10025/3157/6667/336/3156/6604/80205/9439/3992/4199/123/2168/183/116519/6257/3158/376497/9412/9969/405/133522/54797/55090/4899/1374/9440/6721/51/9862/23179/9442/406/19/335/4800/1024/9968/10001/23389/9971/9443/211/9477/1579/51586/400569/6095/6822/80306/8841/5468/29079/4802/4862/90390/6720/6837/9611/2874/81857/2033/8800/9967/6256/51003/7376/10498/948/112950/196/4520/8202/8648/2180/10891/219541 116 Epstein.Barr_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 108/5894 108/10654 1.0987321607046273e-28 4.830987969098158e-27 1.749297255858683e-27 5295/3605/7124/2308/1052/7291/356/3593/246/9021/6624/3082/5743/3091/10538/3383/6097/6657/3576/3662/3688/4985/7133/3606/4609/4988/3717/2162/6347/7040/3312/3569/4692/3596/3598/3592/7412/3911/4582/6367/4312/6778/332/4313/3565/3934/3976/5443/3718/149233/598/2247/2335/595/7157/4128/2353/604/7076/51561/3570/7297/9655/3566/7184/3684/4318/3726/58480/301/6774/6772/8651/1901/3552/79923/112744/3716/240/6356/5008/3586/6095/596/2208/2309/3561/207/5292/5451/7422/3553/2625/3597/4314/1026/3320/4843/6288/948/6935/3687/7431/3929/3162/1278/4170/3689 108 Epstein.Barr_virus R-HSA-418594 G alpha (i) signalling events 328/5894 406/10654 3.8465802108433177e-28 1.6400419262595598e-26 5.938579974635298e-27 729230/2788/10316/6000/2780/1880/5158/7852/50833/29899/6385/5331/5726/338442/64805/2770/817/1237/1258/2550/5578/3000/50832/3354/2841/5582/4987/51289/259294/2912/3576/6360/2775/5530/4985/2920/2921/1236/259295/107/6010/9568/2840/2831/285440/5948/5367/4988/6370/58191/5475/6755/1524/643/2782/5949/5499/339403/4023/2914/8843/2847/2833/10636/9290/5518/9170/6382/187/6121/6750/6004/259296/259289/5998/50835/2587/53829/814/2773/5515/2787/6387/818/4544/4543/126006/10663/4889/9283/727/338398/117579/3579/84152/375790/23566/2358/5567/2916/259293/5594/5179/10681/5142/112/8811/5573/348/56923/2832/5528/1259/27199/2826/8786/6376/165140/27198/111/5443/4836/3627/2792/9397/54429/6714/336/3361/6346/10988/5519/134/5588/6295/1129/51083/2785/2783/2784/1233/6366/5613/2861/2771/728/5332/183/10022/5580/6373/57121/1132/1814/80835/5153/6357/196883/9672/115/8698/801/9934/50840/2791/4647/50865/805/10803/2913/5145/3838/7276/351/11251/3352/8484/6351/6752/2781/1903/84539/6753/5568/3577/2918/5368/6754/131890/8862/301/56670/150/113/2868/335/2853/6751/1208/186/53637/10645/5566/84254/10563/5540/1901/10287/5148/5733/23236/256933/10850/624/4852/816/8601/2786/50838/5577/5473/4283/2239/11255/10874/83756/51109/611/56477/2986/1020/5141/259286/3350/129521/1234/109/9628/5516/151/57007/5533/815/26086/5321/9294/54331/283869/2817/6017/5575/59345/63940/4986/8787/6374/5539/259287/2852/50836/1230/5532/846/4886/2919/51764/94235/114/5330/259290/6383/108/5196/2779/3827/5173/2357/55970/2778/6352/140/10768/346562/152/5957/6364/80834/259292/3949/2793/5030/5697/5576/3355/5534/3351/4035/6288/6372/1235/50834/259285/79823/1385/5144/719/6363/2917/1268/50831/2359/50839/808/388531/5660/1815/1325/1232/1902/10082/50837/1269/59340/4887/2790/718/6003/623 328 Epstein.Barr_virus R-HSA-69206 G1/S Transition 127/5894 131/10654 6.1366048407284625e-28 2.5394714737955727e-26 9.195407872794352e-27 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/4998/5711/5928/10926/5683/990/5699/5702/8900/55388/5518/6117/5001/7465/5558/5696/5691/7314/5515/6241/5718/6118/23594/7027/5700/5707/898/91768/5934/5557/993/890/1876/983/9861/5519/6502/5698/10000/5692/5713/595/4175/5710/5719/6233/7298/7029/23649/1719/1163/4999/4172/26271/1019/5000/8318/54107/4173/5706/286826/891/4331/5714/5111/51053/6119/5688/5687/5427/5708/1874/81620/208/5704/29935/55957/23595/7311/5694/4176/5516/56655/1017/5684/5720/902/8317/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5933/5426/4171/5715/5701/5685/5686/3065/5716/1022/5693/5721/7083 127 Epstein.Barr_virus R-HSA-168273 Influenza Viral RNA Transcription and Replication 129/5894 134/10654 2.3954162054098186e-27 9.629573145747471e-26 3.4868614839649687e-26 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/116832/23225/6156/6143/5439/6139/9972/3921/8021/55746/6208/6170/6203/6171/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/6188/6396/129401/200916/6122/6230/4928/2963/5434/5903/6194/55706/7175/6166/5436/6136/6125/6232/6160/5611/6193/4927/6210/6229/6205/2962/140801/6235/6181/8086/7311/6223/25873/9045/6187/5432/6168/6157/6137/6144/81929/5440/9349/4736/51121/9631/6159/6217/3843/5430/6152/51065/6141/79023/6123/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 129 Epstein.Barr_virus R-HSA-8868773 rRNA processing in the nucleus and cytosol 176/5894 195/10654 6.41873287183674e-27 2.5086547640761927e-25 9.083820789382989e-26 6158/5393/6138/6227/6206/6234/6191/6128/6132/10557/6129/23404/55226/6176/10528/84135/27340/27043/6224/6146/6154/88745/6202/51096/6169/55272/6175/6218/5394/6173/6167/28987/116832/23481/51077/6156/117246/6143/6139/79159/23160/26168/11340/3921/10607/11103/51388/6208/6170/22984/10813/9136/6203/51504/23246/6171/54433/6147/8568/27292/6222/1454/56902/51602/6134/6155/9724/6231/6142/23521/54555/10171/5822/6207/10969/6233/6188/79707/54881/1453/4691/23016/118460/200916/6122/6230/2091/55651/55127/8602/6194/6166/10436/8780/9277/84128/6136/6125/4839/6232/90459/134430/6160/92856/65083/6193/10200/6210/6229/6205/115939/11056/9790/55131/140801/6235/55720/6181/55759/705/7311/6223/25873/55505/51010/26354/56915/51202/9045/57647/6187/6168/6157/6137/79050/22894/84946/6144/9349/55813/4736/57418/22803/51121/6159/25879/6217/81887/6152/57050/51065/6141/6123/55781/6164/6209/11224/6165/6130/6204/1736/6228/10438/10199/51013/6124/83732/27341/6189/6135/6201/6161/54512/10885/6133/9188 176 Epstein.Barr_virus R-HSA-69620 Cell Cycle Checkpoints 247/5894 293/10654 1.042241452536347e-26 3.9633343884287574e-25 1.4351205207043864e-25 5689/55839/11130/9134/83990/11065/6249/5682/9156/57060/9735/1763/7531/7486/7321/5526/10971/8697/9212/5982/7533/2810/147841/348995/11200/143471/472/57122/5705/1780/23122/5048/5709/4174/5695/57405/8655/84515/23279/4194/4998/5711/2491/4683/10926/5683/990/1060/165918/84126/5699/5702/8900/51529/29945/8924/11004/51434/55388/672/9184/5518/6117/29882/7334/5001/23332/7465/25909/51230/10726/81930/55746/5696/83695/5691/7314/996/5515/5718/6118/79682/10403/23594/25936/5700/122706/5707/51588/51720/3619/23198/63967/898/64105/7534/332/5528/993/116028/890/983/51433/9861/79902/3796/9656/5519/81565/5698/5692/5985/5713/91687/119504/11243/4175/5710/7157/5984/7324/83540/5719/64682/6233/7514/7158/54820/6396/64946/9793/5884/5810/140735/4999/220134/4172/80010/4928/5903/5000/8318/246184/55055/51512/1029/80776/1783/401541/7532/79172/4173/5706/9133/79980/6232/580/8881/11073/891/5501/641/5714/54821/6119/9183/3364/10524/5688/1062/699/5687/144715/5708/22919/5529/51143/1111/10393/5704/23595/7311/25906/5347/84643/5983/5694/4176/7529/1778/5516/1017/5905/81929/5684/5720/54908/55143/5883/5525/25946/1058/991/79019/10111/8317/348235/80152/5690/1063/8379/5717/1027/9491/23421/545/55920/79023/10197/7336/29086/1781/7316/10213/4085/1026/4171/55166/5715/9088/7341/5701/5685/5686/995/79003/5527/5716/701/5932/9025/79184/57551/7156/5693/5721/4193 247 Epstein.Barr_virus R-HSA-72312 rRNA processing 183/5894 205/10654 1.6461765719230403e-26 6.095185359725573e-25 2.207062218312331e-25 6158/5393/6138/6227/6206/6234/6191/6128/79922/6132/10557/6129/23404/55226/6176/10528/84135/27340/27043/6224/6146/6154/88745/6202/51096/6169/55272/6175/6218/5394/6173/387338/6167/28987/116832/23481/51077/6156/117246/6143/6139/79159/23160/26168/11340/3921/10607/11103/51388/6208/6170/22984/10813/60528/9136/6203/51504/23246/6171/54433/6147/8568/27292/6222/1454/56902/130916/51602/6134/6155/9724/6231/6142/23521/54555/10171/5822/6207/10969/6233/6188/79707/54881/1453/4691/23016/118460/200916/6122/6230/2091/55651/55127/8602/6194/6166/3028/10436/8780/9277/84128/6136/6125/4839/6232/90459/134430/6160/92856/65083/6193/10200/6210/6229/6205/115939/11056/9790/55131/140801/6235/55720/6181/55759/705/7311/6223/25873/55505/51010/26354/56915/51202/9045/51106/57647/6187/6168/6157/6137/79050/22894/84946/6144/9349/55813/4736/57418/22803/51121/6159/25879/6217/81887/6152/57050/51065/6141/6123/55781/6164/54931/6209/11224/6165/6130/6204/1736/6228/10438/10199/51013/6124/83732/27341/6189/6135/6201/6161/54512/10885/6133/9188 183 Epstein.Barr_virus R-HSA-72613 Eukaryotic Translation Initiation 116/5894 119/10654 2.3427009862318116e-26 8.240450719070397e-25 2.983861256147886e-25 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/116832/6156/6143/1973/6139/3921/8665/6208/6170/6203/6171/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/1978/200916/6122/1968/6230/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/8893/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/8891/51121/6159/6217/6152/51065/6141/10480/6123/1967/6164/8661/9669/6209/1964/11224/6165/6130/8890/6204/6228/6124/3646/6189/6135/6201/6161/8892/6133 116 Epstein.Barr_virus R-HSA-72737 Cap-dependent Translation Initiation 116/5894 119/10654 2.3427009862318116e-26 8.240450719070397e-25 2.983861256147886e-25 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/116832/6156/6143/1973/6139/3921/8665/6208/6170/6203/6171/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/1978/200916/6122/1968/6230/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/8893/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/8891/51121/6159/6217/6152/51065/6141/10480/6123/1967/6164/8661/9669/6209/1964/11224/6165/6130/8890/6204/6228/6124/3646/6189/6135/6201/6161/8892/6133 116 Epstein.Barr_virus R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 167/5894 185/10654 1.2870932731319675e-25 4.41692740316263e-24 1.5993662238661673e-24 6158/5393/6138/6227/6206/6234/6191/6128/6132/10557/6129/23404/6176/10528/84135/27340/27043/6224/6146/6154/88745/6202/51096/6169/55272/6175/6218/5394/6173/6167/28987/116832/23481/51077/6156/117246/6143/6139/79159/23160/26168/11340/3921/10607/11103/51388/6208/6170/22984/10813/9136/6203/23246/6171/6147/8568/6222/1454/56902/51602/6134/6155/9724/6231/6142/23521/54555/10171/5822/6207/10969/6233/6188/79707/54881/1453/4691/23016/118460/200916/6122/6230/2091/55127/8602/6194/6166/10436/8780/9277/84128/6136/6125/6232/90459/134430/6160/92856/65083/6193/10200/6210/6229/6205/11056/9790/55131/140801/6235/55720/6181/55759/705/7311/6223/25873/51010/26354/56915/51202/9045/57647/6187/6168/6157/6137/79050/22894/84946/6144/9349/55813/4736/57418/22803/51121/6159/25879/6217/81887/6152/57050/51065/6141/6123/55781/6164/6209/11224/6165/6130/6204/6228/10438/10199/51013/6124/83732/27341/6189/6135/6201/6161/54512/10885/6133/9188 167 Epstein.Barr_virus R-HSA-3858494 Beta-catenin independent WNT signaling 137/5894 146/10654 1.6282843170327088e-25 5.454752462059574e-24 1.975161928430654e-24 2788/5689/2780/5158/5579/5682/5331/5578/1212/5582/27327/143471/5705/2775/5530/5709/5695/5881/5711/5683/5699/2782/5702/192669/57216/1855/6932/163/4343/5593/3845/5696/5691/4920/7314/5879/2787/5718/51176/2535/161/51701/5700/122706/5707/1856/8322/23198/10681/7471/83439/8323/2792/9861/7481/5698/5880/5692/5713/2785/2783/23002/2784/5710/5719/6233/7474/1857/1213/1211/7855/1175/26523/801/2791/7976/805/5145/1173/144165/4772/409/5706/160/5714/6934/5688/5687/5148/4919/23236/5708/2786/5704/7311/387/5694/57154/27161/815/5684/5720/54331/6885/1499/59345/5690/5532/57690/5717/9491/50855/51764/94235/5330/10197/192670/64750/7316/10213/55970/5216/5715/5701/2793/5685/5686/5534/23112/23513/5716/808/5693/5721/6259/2790/5592 137 Epstein.Barr_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 368/5894 473/10654 1.8006177598711607e-25 5.8917888096249375e-24 2.133412474363872e-24 5295/374/5777/627/3643/9252/4893/857/2250/2670/5335/71/5579/5770/5291/1848/5578/1785/5908/3082/51741/23385/2064/535/1280/1289/54845/5431/8829/6696/6776/5435/3688/10312/5433/5753/5327/4734/10413/5605/3910/8569/5898/1432/3717/55824/145957/2534/9475/3690/9965/2242/1215/5439/2264/5603/3630/6456/83737/6868/7072/4145/9542/30011/2885/2475/8660/6093/163/7073/6196/9846/1759/5518/8440/2252/9564/2253/6197/3845/3265/1399/3071/8877/5062/4486/10603/10252/51231/5829/7314/5879/5515/6387/5607/54106/26999/1839/3918/161/5290/3667/8823/2065/5340/3815/5567/8027/10006/537/3911/9550/1849/1284/2060/9114/5594/2069/8074/284217/9101/23118/57761/5921/6778/2260/5438/348/5528/9306/1500/1795/3185/11059/102/9261/2249/6714/2099/5664/2248/1447/5519/5598/4208/4670/2567/4909/2321/2247/4914/529/10810/10000/9146/6455/2335/64759/6195/3728/8471/1445/3925/6233/7525/7410/5580/2324/7409/2246/23191/3685/1292/2251/3932/1213/3791/1729/1211/29924/1535/5600/6777/1175/523/6300/528/801/200734/5781/30849/5663/5725/1302/1291/10787/1846/253260/805/25920/5170/4908/1173/4688/2963/5434/5590/6464/85440/653361/5241/2904/6461/5747/5782/135/5436/10193/5568/2322/7074/3315/2241/10451/4318/382/1277/160/3912/1793/673/527/6774/2263/4233/10152/6772/8651/7867/64223/5566/5802/2962/1003/8503/5795/2889/10163/5159/4067/3084/55845/5063/5771/1111/998/7058/3481/3913/208/6654/83464/5867/10718/79109/7006/7311/2185/387/1956/60/55851/2549/51107/5058/1020/5432/3480/22916/11140/53916/4916/7529/63916/5595/25759/5516/1845/10253/9402/5440/1282/8065/685/558/4915/1495/5604/1499/4690/5430/10048/10273/207/7422/10458/5045/3178/8817/5441/58513/2254/4686/7316/152831/1950/9611/9047/4205/5289/57498/3915/10768/26281/10818/8936/3673/2261/6014/867/5437/466/2255/3320/4846/4803/2002/2066/27006/6285/1742/1398/3187/4689/6016/1385/9844/5228/5906/3479/5155/23163/4254/8851/5296/5581/581/808/10076/1536/7057/1278/10254/6457/51382/5156/161742/2887 368 Epstein.Barr_virus R-HSA-373076 Class A/1 (Rhodopsin-like receptors) 274/5894 335/10654 2.9680262377594657e-25 9.490938446653565e-24 3.4366619595109604e-24 729230/2532/4160/10316/2149/23620/1880/7852/10161/338442/64805/1237/5734/3354/2841/4987/51289/2150/3060/6349/3576/6360/2798/5737/338557/4985/2920/3061/2921/1236/6010/2840/2831/5367/5028/4988/6370/58191/6755/6866/1524/94233/643/5029/2867/185/339403/8843/64106/2847/2833/6347/9290/9170/187/6750/2587/53829/8111/6387/4544/4543/2922/10663/4889/9283/727/1909/117579/3579/6375/23566/2358/1131/6846/5179/27334/5021/6865/6367/2797/8811/1812/56923/2832/2693/27199/2826/6376/165140/27198/7201/5443/6354/3627/3361/6346/553/257313/134/9034/59350/3814/10800/2863/1129/51083/2829/1233/6366/1241/2861/728/183/10022/6373/57121/4922/5731/2865/1132/1814/6357/552/2925/8698/9934/2151/6869/6361/2147/1813/50865/10886/2837/10803/146/3357/351/11251/8477/84432/3352/8484/2828/3062/1907/148/6351/6863/6752/135/1903/84539/6753/3577/594857/5368/6754/6915/8862/10911/301/5032/56670/150/2853/29933/6751/5020/4935/887/4829/186/53637/60675/51738/10563/5540/2864/1901/5733/256933/7200/5729/10850/624/2796/4852/4828/680/5473/4283/1910/6870/128674/11255/885/10874/84634/147/6356/611/56477/387129/3350/129521/1234/151/57007/1238/3356/84109/9294/4923/1128/283869/4986/6374/5539/2852/1230/3358/4886/2919/1908/5196/3827/5173/2357/6352/57105/1133/140/3269/6348/886/2862/152/1906/6364/7253/5031/8620/5030/5697/56413/3355/3351/6288/6372/1235/719/6363/1268/2359/347148/2846/5660/1815/1325/1232/4295/1902/551/154/9002/1269/3274/59340/5724/4887/718/623 274 Epstein.Barr_virus R-HSA-376176 Signaling by ROBO receptors 191/5894 218/10654 3.0535174589096e-25 9.547331254857348e-24 3.457081754648529e-24 6158/5689/6138/6227/7852/6206/6234/6191/6128/5682/6132/10298/6129/6176/5578/6224/6146/6154/26986/143471/6202/5705/6169/8829/23122/5709/9978/6175/6218/5695/65109/6173/6167/5711/116832/1605/5683/6156/5699/6143/9495/5702/6139/10487/8440/3921/23332/5062/6208/5696/6170/5691/7314/5879/6387/5718/25/6203/8861/6171/6147/5700/122706/5707/5567/6222/23198/27/26019/2935/6134/22794/6155/4116/6714/6231/9861/6142/23521/10486/5698/5692/5713/1981/5710/6207/5719/6233/6188/5217/200916/6122/6230/6194/2107/6166/56924/6136/5568/6125/5706/3670/6232/6160/55110/5714/6193/6210/6229/6205/5566/4650/5688/5687/5708/5063/140801/6235/6181/998/9939/6654/5704/7311/6223/25873/387/23708/5694/5058/9045/6187/65110/6168/22916/6157/6137/10921/6144/55740/23032/5684/9349/4736/5720/51121/2817/6159/4690/6217/6152/5690/5532/5717/9491/51065/6141/23053/6123/10197/6164/4686/7316/10213/5216/6209/11224/6165/6130/5715/6204/5701/6228/5576/5685/51466/5686/7408/6124/8453/5716/23380/1630/6189/9775/6135/6201/6161/5693/5721/6133 191 Epstein.Barr_virus R-HSA-68886 M Phase 315/5894 395/10654 3.350644333147638e-25 1.024860125377984e-23 3.7110111149735845e-24 114791/10844/23165/5689/55839/11130/11065/440145/6249/5579/5682/9735/7531/1459/11190/7321/91754/203068/5526/54801/51807/8697/5578/9212/347688/10274/5861/5925/1460/147841/348995/79441/143471/10381/57122/5705/5116/1780/23122/23511/5048/5709/5695/57405/8655/1457/23279/9702/5711/2491/10112/7846/23225/7840/5683/1060/5699/9663/11064/5702/5520/81027/51529/4001/29945/11004/23133/51434/9184/9972/5518/55844/55835/29922/8021/29882/23332/84930/25909/10726/81930/55746/93323/5696/5691/7314/996/5515/5718/79682/10403/79861/64151/25936/55869/5700/122706/5707/1454/2801/5594/3619/23198/64105/23310/332/10762/10051/5528/983/8548/51433/9861/79902/3796/8615/79959/5519/9883/81565/221496/2029/7444/5698/5692/5713/80097/91687/119504/11243/10376/23397/5710/10540/85378/7324/83540/2010/64900/5719/64682/6233/23175/7514/54930/54820/113130/9493/6396/129401/1453/27229/64946/9793/140735/220134/84617/4928/26271/5903/55706/7175/11258/22981/246184/55055/8636/80776/1783/401541/7532/55125/10382/79172/121441/7277/5706/9133/79980/25836/6232/23047/8881/9814/653784/5885/23354/891/5501/9738/1639/5714/55722/4957/4927/5566/54821/81876/9183/5688/1062/699/5687/7283/347733/5708/22919/8243/10426/5529/22994/51143/1069/8086/10393/79648/5577/5704/7311/25906/10383/5347/54892/84790/84643/80184/5694/22897/6418/5108/7112/10592/7280/10806/29781/5595/1778/5516/4000/115106/4926/5905/22995/55559/81929/5684/5720/54908/55143/9631/5525/10142/1058/991/79019/5862/348235/80152/5690/1063/8379/95681/5717/9491/140609/10783/23244/23421/55920/79023/23636/10735/10197/7443/23141/1781/7316/10213/80321/10776/53371/26003/4085/9688/55166/10121/5715/84131/5701/5685/3320/8815/5686/79003/9126/9918/10733/4751/9232/23592/9700/5527/27175/80254/5716/701/57551/9662/55142/64689/8481/5693/5721/55755/8480 315 Epstein.Barr_virus R-HSA-375276 Peptide ligand-binding receptors 178/5894 201/10654 7.619799634425477e-25 2.281076188433329e-23 8.259760409993126e-24 729230/2532/4160/10316/2149/23620/7852/1237/4987/51289/2150/3060/6349/3576/6360/4985/2920/3061/2921/1236/2831/5367/4988/6370/58191/6755/6866/1524/643/185/339403/64106/2847/2833/6347/187/6750/2587/6387/2922/10663/4889/9283/727/1909/117579/3579/6375/2358/6846/5179/5021/6865/6367/8811/56923/2832/2693/2826/6376/7201/5443/6354/3627/6346/553/257313/9034/59350/3814/51083/2829/1233/6366/2861/728/183/10022/6373/4922/6357/552/2925/2151/6869/6361/2147/50865/10886/2837/10803/351/84432/8484/3062/1907/6351/6863/6752/84539/6753/3577/594857/5368/6754/8862/10911/301/6751/5020/887/4829/186/60675/51738/10563/5540/256933/7200/10850/624/4852/4828/680/5473/4283/1910/6870/128674/885/10874/84634/6356/56477/387129/129521/1234/57007/1238/84109/4923/283869/4986/6374/5539/2852/1230/4886/2919/1908/5196/3827/5173/2357/6352/6348/886/2862/1906/6364/8620/5697/6288/6372/1235/719/6363/2359/347148/5660/1325/1232/4295/551/9002/4887/718/623 178 Epstein.Barr_virus R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 109/5894 112/10654 1.3060856088712468e-24 3.8284634410038426e-23 1.3862838480124635e-23 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/6202/6169/6175/6218/6173/6167/116832/6156/6143/1973/6139/3921/8665/6208/6170/6203/6171/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/200916/6122/1968/6230/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/9669/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 109 Epstein.Barr_virus R-HSA-168898 Toll-like Receptor Cascades 143/5894 155/10654 1.67412401739806e-24 4.8071275356715727e-23 1.7406574101410549e-023 8454/3725/9252/4790/7321/1848/1785/6280/10333/4792/59307/177/1432/2244/929/3654/51135/6196/1759/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/54106/23098/11035/8945/1326/5601/6283/5606/11213/8737/8767/5336/1849/29110/5594/6271/4214/28512/23118/841/8517/5528/7323/1515/5970/7096/9261/5519/5598/4208/6195/10454/3661/6233/51311/10010/2266/2353/2243/8772/5600/5781/30849/5608/4791/671/1508/1846/1514/3665/351/81793/7184/653509/3684/8411/330/51295/7098/79155/6279/8651/7867/64127/5602/3656/57162/695/7189/81622/7311/9641/6416/51284/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7100/7316/7335/1513/4205/5289/4793/5641/5775/3146/7322/329/466/23291/114609/6288/2002/6285/5609/948/1520/1385/5599/7097/3929/57161/3689/148022 143 Epstein.Barr_virus R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 108/5894 111/10654 2.316871194775215e-24 6.519675542097455e-23 2.360769806886745e-23 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/116832/6156/6143/1973/6139/3921/8665/6208/6170/6203/6171/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/200916/6122/1968/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 108 Epstein.Barr_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 126/5894 134/10654 8.641738841231838e-24 2.3841032450221953e-22 8.632820638093312e-23 5295/8454/5689/3725/4893/5335/4790/5682/5291/7321/143471/5705/5530/5709/5695/4792/5711/5683/2534/5699/5702/2885/9846/3845/7334/3265/3551/5062/5696/5691/7314/5879/7294/257397/5718/8945/5601/4773/5290/5700/122706/5707/5336/5594/4214/23198/23118/10892/8517/5970/9861/5588/5698/5692/5713/5710/10454/5719/6233/7410/7409/3702/2353/801/805/5170/6464/2205/4772/3937/4775/10451/5706/2206/6850/8915/5714/5688/5687/4067/5708/5602/695/7189/6654/5704/7006/7311/5694/5058/6416/997/5595/1147/9402/5684/5720/6885/84433/5690/5532/5717/9491/6500/10197/7316/10213/7335/10768/7462/7322/5715/5701/27040/23291/5685/5686/5534/5609/5716/5296/808/5599/5693/5721/2207 126 Epstein.Barr_virus R-HSA-162909 Host Interactions of HIV factors 122/5894 129/10654 1.0069824325407335e-23 2.7246620818938694e-22 9.865981727727024e-23 23165/5689/162/5682/1174/348995/143471/57122/5705/23511/5709/9978/5695/292/567/23279/5711/23225/5683/2534/5699/5702/3836/163/9972/8021/1794/904/5062/55746/5696/5691/7314/5879/5718/8945/161/5700/122706/5707/10053/23198/10762/926/9861/79902/11168/9883/5698/5692/5713/5710/5902/5478/5719/6233/7514/1025/3932/6396/129401/1175/8907/940/60489/1173/4928/5903/55706/7175/4869/5706/160/293/920/5714/4927/5688/5687/5708/5901/8086/5704/7311/8905/5694/1104/5905/3837/81929/164/5684/8065/5720/9631/3159/5690/5717/9491/6500/79023/23636/10197/919/130340/7316/10213/53371/3055/9688/5715/5701/5685/8815/5686/5716/9844/375/5693/5721/8480/291 122 Epstein.Barr_virus R-HSA-202403 TCR signaling 114/5894 119/10654 1.0823086949645695e-23 2.873223271349338e-22 1.0403920722201621e-22 5295/8454/5689/5335/4790/5682/5291/7321/143471/5705/5788/3115/5709/5695/4792/3113/5711/3117/5683/55824/5699/5702/26191/3127/7334/3551/5062/5696/5691/7314/5718/8945/3635/5290/5700/122706/5707/8767/23198/23118/10892/8517/3126/5970/9861/5588/5698/5692/5713/1445/5710/916/5719/6233/3702/3932/3120/5170/3937/3123/5706/3122/920/8915/5714/5795/5688/5687/5708/5063/7189/7535/5704/7311/3125/5694/5058/997/1147/55740/9402/5684/5720/6885/4690/3119/84433/5690/5717/9491/6500/10197/919/7316/10213/7335/50852/7322/5715/5701/27040/23291/915/5685/917/51466/5686/7408/5728/7454/5716/5296/5693/5721 114 Epstein.Barr_virus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 154/5894 171/10654 1.9025227891460246e-23 4.957128822830476e-22 1.7949727679272433e-22 6158/5689/6138/6227/6206/6234/6191/6128/5682/6132/6129/6176/6224/6146/6154/26986/143471/6202/5705/6169/5709/9978/6175/6218/5695/65109/6173/6167/5711/116832/1605/5683/6156/5699/6143/5702/6139/3921/6208/5696/6170/5691/7314/5718/6203/8861/6171/6147/5700/122706/5707/6222/23198/26019/2935/6134/22794/6155/4116/6231/9861/6142/23521/5698/5692/5713/1981/5710/6207/5719/6233/6188/200916/6122/6230/6194/2107/6166/6136/6125/5706/3670/6232/6160/55110/5714/6193/6210/6229/6205/5688/5687/5708/140801/6235/6181/9939/5704/7311/6223/25873/23708/5694/9045/6187/65110/6168/22916/6157/6137/10921/6144/23032/5684/9349/4736/5720/51121/6159/6217/6152/5690/5717/9491/51065/6141/23053/6123/10197/6164/4686/7316/10213/6209/11224/6165/6130/5715/6204/5701/6228/5685/5686/6124/8453/5716/6189/9775/6135/6201/6161/5693/5721/6133 154 Epstein.Barr_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 93/5894 94/10654 3.802736499497387e-23 9.728091372350589e-22 3.522534862692316e-22 8454/3725/9252/4790/7321/1848/4792/177/1432/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/23098/11035/8945/1326/5601/6283/5606/8737/8767/1849/29110/5594/28512/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5608/4791/1846/3665/351/330/7098/79155/7867/64127/5602/3656/7189/7311/9641/6416/28511/5595/5516/1147/1845/6885/5604/10392/6500/7316/7335/4205/4793/3146/7322/329/466/23291/6288/2002/6285/5609/1385/5599/148022 93 Epstein.Barr_virus R-HSA-446652 Interleukin-1 family signaling 130/5894 140/10654 4.4652297224697015e-23 1.1022067051780475e-21 3.9910825220227797e-22 8454/834/5689/5777/4790/5682/1511/5783/27178/8878/143471/5705/5709/9978/5695/4792/59307/3606/177/5711/4088/5683/84867/5699/5702/3654/51135/7334/3551/5696/5691/7314/3596/257397/5718/8945/1326/6283/90865/11213/5700/122706/5707/8767/29110/23198/28512/23118/8517/3565/5970/8807/8809/9861/5698/5692/5713/5710/10454/5719/6233/7850/5781/5608/4791/3557/56300/351/5782/54472/5706/79155/6774/5780/5714/64127/3552/5688/5687/5708/3656/57162/5771/7189/5704/84639/7311/240/5694/6416/3554/28511/3556/1147/5778/5684/5720/6885/5604/4215/10392/5690/3553/5717/9491/6500/25930/10197/4615/26525/7316/10213/7335/4793/5775/3146/5715/5701/23291/5685/5686/6288/6285/5716/9173/5599/5784/57161/5693/5721 130 Epstein.Barr_virus R-HSA-6807070 PTEN Regulation 130/5894 140/10654 4.4652297224697015e-23 1.1022067051780475e-21 3.9910825220227797e-22 1912/5689/3725/6591/5682/1822/1459/9112/6045/27327/80012/1460/143471/5705/5709/5695/1457/1911/4734/11060/5711/5928/5683/23512/57332/5699/2444/5702/192669/1107/8975/5371/2475/1386/4343/80351/5696/5691/7314/5718/23186/5700/122706/5707/2146/51564/5594/84232/23198/9861/7101/81847/84733/57459/5698/10000/5692/5713/5710/3066/7157/5719/6233/331/8726/26523/7874/57521/23608/6015/28956/389541/9219/8535/5931/5706/8658/5714/1108/2122/64223/10014/5688/5687/5708/54815/6009/208/5704/55004/57504/7311/648/5694/23466/53615/5595/27161/5684/8841/5720/5468/5978/10273/207/5690/57690/5717/9491/10197/192670/7316/10213/57167/5715/1958/5701/5685/8649/5686/5728/6615/3065/23028/5987/23112/10542/5716/5693/5721 130 Epstein.Barr_virus R-HSA-5357801 Programmed Cell Death 161/5894 181/10654 4.6214278591288763e-23 1.1210946547921256e-21 4.0594756512130237e-22 5689/5682/7531/55075/356/10971/10059/7533/2810/143471/5705/5709/1869/5695/8655/660/5711/836/5683/929/324/5699/9414/5702/90427/4001/3836/6709/6093/840/7159/26060/637/5062/5696/5691/7314/578/23368/5718/2934/11035/22985/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/100506658/7082/5339/4836/8797/9861/28988/10134/22900/999/5588/598/5698/10000/5692/708/5713/5710/3002/7157/5719/6233/5580/1613/839/7029/8772/331/8717/57099/317/8743/140735/1828/5747/1029/572/7532/330/118/5706/1829/6774/5366/5714/8428/5688/5687/1832/56616/5708/8837/8626/197259/208/5704/7311/7161/5694/8795/3148/7529/5595/23643/4000/5533/27113/3837/1676/596/5684/5720/7186/51765/1499/10018/842/207/5690/5717/9491/355/10197/7099/9500/7316/10213/54205/3146/5715/23604/5701/329/5685/5686/5534/4137/5716/1677/1630/581/5599/7431/5693/5721/6304/148022 161 Epstein.Barr_virus R-HSA-416476 G alpha (q) signalling events 187/5894 217/10654 7.955446676960102e-23 1.8971717753360786e-21 6.869645301781782e-22 5295/2788/10316/2149/23620/8526/4893/10161/5331/5578/2150/3060/5583/2769/2798/5737/338557/3061/2911/2840/5367/5028/6866/94233/5029/2782/2867/2776/185/2885/6196/64106/2847/8997/9170/6197/3845/6004/3265/5998/8111/2787/2922/1839/5290/1909/6375/23566/2358/7225/1131/6846/5594/27334/10681/5021/6865/2797/56923/2693/7201/2792/553/257313/5598/3814/10800/5588/2863/2785/6195/2783/2784/2829/222545/8525/1241/5332/183/5580/57121/115557/4922/5731/2865/552/2925/2151/6869/2791/2147/10886/2520/2837/146/3357/351/8477/84432/2828/3062/1907/148/7204/6863/84539/594857/6915/10911/301/5032/2642/29933/5020/4935/887/4829/60675/51738/8503/2864/10287/23236/7200/624/2641/2796/4828/695/2786/680/6654/1910/6870/128674/885/1956/10874/84634/147/387129/129521/5595/3356/84109/54331/4923/1128/59345/846/3358/1908/51764/94235/5330/3827/55970/57105/1133/4314/3269/2767/886/2862/1906/5031/8620/2793/56413/6288/2869/1385/5997/5296/5581/347148/2846/9630/4295/1902/551/9002/2915/5724/2790/6003/623 187 Epstein.Barr_virus R-HSA-927802 Nonsense-Mediated Decay (NMD) 110/5894 115/10654 1.0049862140222994e-22 2.318058365785861e-21 8.393672607192285e-22 6158/9887/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/65109/6173/6167/116832/6156/6143/5520/6139/23381/5518/3921/6208/6170/5515/6203/6171/6147/6222/26019/2935/6134/22794/6155/4116/6231/6142/23521/1981/6207/6233/6188/23049/5976/200916/6122/6230/6194/2107/6166/6136/6125/6232/6160/55110/6193/6210/6229/6205/140801/6235/6181/9939/7311/6223/25873/23708/9045/6187/65110/6168/22916/6157/6137/10921/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/4686/6209/11224/6165/6130/6204/6228/55802/6124/6189/23293/9775/6135/6201/6161/6133 110 Epstein.Barr_virus R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 110/5894 115/10654 1.0049862140222994e-22 2.318058365785861e-21 8.393672607192285e-22 6158/9887/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/65109/6173/6167/116832/6156/6143/5520/6139/23381/5518/3921/6208/6170/5515/6203/6171/6147/6222/26019/2935/6134/22794/6155/4116/6231/6142/23521/1981/6207/6233/6188/23049/5976/200916/6122/6230/6194/2107/6166/6136/6125/6232/6160/55110/6193/6210/6229/6205/140801/6235/6181/9939/7311/6223/25873/23708/9045/6187/65110/6168/22916/6157/6137/10921/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/4686/6209/11224/6165/6130/6204/6228/55802/6124/6189/23293/9775/6135/6201/6161/6133 110 Epstein.Barr_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 91/5894 92/10654 1.2333885018084017e-22 2.7989961645877764e-21 1.0135144904503673e-21 6884/6875/5563/83990/9156/1763/1459/7486/6874/9212/5982/1460/11200/472/53632/28996/1457/6790/4194/1432/4683/84126/8900/6873/672/6881/51616/6117/11198/83695/7314/1263/6118/51422/116028/890/83860/5985/7157/5984/6233/5600/6883/5884/5810/26155/80010/8445/204851/6878/580/11073/641/8148/6119/3364/5571/10524/54457/144715/6794/94241/1111/7311/5562/6880/6908/5983/5564/6882/5565/1020/6877/1017/9891/5883/10111/22974/6749/545/8550/7316/6872/6879/112858/5932/8851/5300/7156/138474/4193 91 Epstein.Barr_virus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 84/5894 84/10654 1.9398785022794995e-22 4.3323953217575486e-21 1.5687572182176738e-21 10445/5982/6613/7507/9978/85015/10980/2965/10987/2067/2967/6612/6117/7334/10714/7314/6118/83444/404672/9557/86/3978/1643/29844/5985/10920/2068/5984/54891/6233/93973/8607/5424/5886/8451/8554/7515/54107/8450/4331/5425/5111/2966/6119/5427/1642/142/125476/2071/1069/7329/51426/2873/7311/3980/60/8533/5983/10038/51138/7528/56655/9318/902/57804/7336/2072/54778/7316/64708/5426/283899/7341/4798/79913/10401/54617/2968/5887/2073/5981/1022/50813/7508 84 Epstein.Barr_virus R-HSA-109581 Apoptosis 158/5894 178/10654 1.9843724446666088e-22 4.3625187963217475e-21 1.5796649066096029e-21 5689/5682/7531/55075/356/10971/10059/7533/2810/143471/5705/5709/1869/5695/8655/660/5711/836/5683/929/324/5699/9414/5702/90427/4001/3836/6709/6093/840/7159/26060/637/5062/5696/5691/7314/578/23368/5718/2934/22985/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/100506658/7082/5339/4836/8797/9861/28988/10134/22900/999/5588/598/5698/10000/5692/708/5713/5710/3002/7157/5719/6233/5580/1613/839/7029/8772/331/8717/57099/317/8743/140735/1828/5747/1029/572/7532/118/5706/1829/6774/5366/5714/8428/5688/5687/1832/56616/5708/8837/8626/208/5704/7311/7161/5694/8795/3148/7529/5595/23643/4000/5533/27113/3837/1676/596/5684/5720/7186/51765/1499/10018/842/207/5690/5717/9491/355/10197/7099/9500/7316/10213/54205/3146/5715/23604/5701/329/5685/5686/5534/4137/5716/1677/1630/581/5599/7431/5693/5721/6304/148022 158 Epstein.Barr_virus R-HSA-9020702 Interleukin-1 signaling 100/5894 103/10654 2.2447697909319073e-22 4.8590632243710675e-21 1.7594632855239562e-21 8454/5689/4790/5682/8878/143471/5705/5709/9978/5695/4792/177/5711/5683/5699/5702/3654/51135/7334/3551/5696/5691/7314/257397/5718/8945/1326/6283/11213/5700/122706/5707/8767/23198/28512/23118/8517/5970/9861/5698/5692/5713/5710/10454/5719/6233/7850/5608/4791/3557/351/54472/5706/79155/5714/64127/3552/5688/5687/5708/3656/57162/7189/5704/7311/5694/6416/3554/28511/3556/1147/5684/5720/6885/5604/4215/10392/5690/3553/5717/9491/6500/10197/4615/7316/10213/7335/4793/3146/5715/5701/23291/5685/5686/6288/6285/5716/57161/5693/5721 100 Epstein.Barr_virus R-HSA-69052 Switching of origins to a post-replicative state 89/5894 90/10654 3.997319107209482e-22 8.521557551278395e-21 3.0856498371441616e-21 8454/5689/9134/11065/5682/7321/8697/143471/5705/5709/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/29882/5001/5696/5691/7314/996/5718/23594/5700/122706/5707/23198/898/890/51433/9861/6502/5698/5692/5713/119504/4175/5710/7324/5719/64682/6233/4999/4172/5000/246184/4173/5706/8881/5714/5688/5687/5708/81620/10393/5704/51343/23595/7311/25906/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 89 Epstein.Barr_virus R-HSA-162587 HIV Life Cycle 138/5894 152/10654 5.944831260635649e-22 1.2484145647334864e-20 4.520500125919331e-21 6884/23165/6875/51652/2237/7852/27243/6874/348995/57122/55048/3981/5431/23511/5435/5433/2960/51271/23279/23327/29082/23225/2965/27183/5439/6873/3836/9972/6881/2967/51616/8021/11198/904/51497/55746/92421/7314/137492/25978/51160/2959/7518/404672/10015/91782/5438/3978/10762/79720/51534/4836/9397/79902/11168/9883/89853/83860/51510/2068/5902/5478/6233/7514/1025/6396/129401/6883/7936/6829/2957/25920/4928/2963/5434/5903/55706/7175/79643/5436/6878/920/4331/4927/8148/2966/2962/54457/8812/128866/905/2071/5901/8086/7311/93343/6880/6908/7251/1104/2547/6882/2961/5432/22916/155382/1234/6877/5905/6917/81929/5440/902/9631/3159/5430/5045/7520/6749/79023/5441/23636/4686/7316/6872/53371/9688/8731/6879/9525/2958/5437/8815/2968/138474/1022/8178/8480 138 Epstein.Barr_virus R-HSA-72689 Formation of a pool of free 40S subunits 98/5894 101/10654 7.018187058030164e-22 1.452145469213006e-20 5.258208260195974e-21 6158/6138/6227/6206/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/8665/6208/6170/6203/6171/6147/8666/6222/8667/6134/6155/6231/6142/8663/23521/6207/6233/51386/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/8664/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 98 Epstein.Barr_virus R-HSA-8878166 Transcriptional regulation by RUNX2 114/5894 121/10654 7.793498945344025e-22 1.5891960892897164e-20 5.754467566051118e-21 8454/8493/5689/7291/5682/5925/143471/5705/5709/9978/5695/9759/10413/4089/3549/5711/5683/2101/1749/5699/5702/5696/5691/7314/5718/25/6662/5700/122706/5707/5594/3280/23198/100526737/10013/2737/865/11059/983/6714/2099/9861/2932/6502/5698/10000/5692/5713/595/5710/5719/6233/7525/10432/133522/4091/117581/1019/3958/5706/3678/1277/891/579/5714/6772/2736/5688/5687/4322/2908/5708/4488/208/5704/23493/7311/367/860/1750/5694/5595/57154/5684/8841/5720/23462/10273/207/5690/5717/9491/6500/4086/59269/10197/7316/10213/4094/1026/5715/5701/5685/5686/55294/23314/861/25925/5716/25937/581/5693/5721/10891 114 Epstein.Barr_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 93/5894 95/10654 8.247227272458398e-22 1.6116456628262453e-20 5.835757309751264e-21 8454/3725/9252/4790/1848/10333/4792/59307/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/11213/8767/1849/5594/4214/28512/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/7335/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/57161 93 Epstein.Barr_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 93/5894 95/10654 8.247227272458398e-22 1.6116456628262453e-20 5.835757309751264e-21 8454/3725/9252/4790/1848/10333/4792/59307/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/11213/8767/1849/5594/4214/28512/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/7335/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/57161 93 Epstein.Barr_virus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 93/5894 95/10654 8.247227272458398e-22 1.6116456628262453e-20 5.835757309751264e-21 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6171/6147/6222/2935/6134/6155/6231/6142/23521/1981/6207/6233/6188/5976/200916/6122/6230/6194/2107/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/23708/9045/6187/6168/22916/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/4686/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 93 Epstein.Barr_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 87/5894 88/10654 1.2944766371220738e-21 2.4949707238777503e-20 9.034270978616924e-21 5393/5689/5682/23404/5578/26986/143471/5705/5709/5695/5711/1432/5683/5699/5702/11340/8021/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/7534/9261/8741/9861/5698/5692/5713/1981/5710/5719/6233/5580/7514/5600/8570/23016/118460/1994/5073/3842/3315/5706/8125/677/7538/5714/5688/5687/5708/5704/7311/51010/5694/56915/3304/6418/167227/7529/22894/5684/5720/207/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/55802/51013/5716/54464/5693/54512/5721 87 Epstein.Barr_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 120/5894 129/10654 1.4311935378000666e-21 2.7212017671414776e-20 9.853451952990499e-21 8454/3725/9252/4790/7321/1848/1785/10333/4792/59307/177/1432/929/3654/51135/6196/1759/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/23098/11035/8945/1326/5601/6283/5606/11213/8737/8767/5336/1849/29110/5594/4214/28512/23118/841/8517/5528/7323/5970/7096/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/671/1846/3665/351/653509/3684/330/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/9641/6416/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/7335/4205/4793/5775/3146/7322/329/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/3929/57161/3689/148022 120 Epstein.Barr_virus R-HSA-500792 GPCR ligand binding 356/5894 468/10654 1.4526697247531196e-21 2.725208403636852e-20 9.867959954814173e-21 729230/2788/2532/4160/10316/2149/23620/1880/7852/10161/50833/5726/338442/64805/1237/5734/2550/50832/3354/2841/4987/51289/259294/2150/3060/2912/6349/3576/6360/2798/5737/338557/4985/2920/3061/2921/1236/259295/6010/9568/2911/2840/2831/5367/3549/5028/5741/4988/6370/58191/6755/6866/1524/94233/643/5029/2782/2867/185/339403/2914/8843/64106/2847/2833/6347/9290/9170/6469/187/6750/259296/259289/50835/2587/53829/8111/2787/6387/4544/4543/2922/10663/4889/2535/9283/727/7476/1909/338398/117579/3579/6375/23566/2358/2916/259293/1131/8322/6846/5179/27334/10681/5021/6865/6367/7471/2797/8811/1812/56923/2832/2693/27199/2826/5727/6376/165140/27198/7201/89780/5443/8323/6354/3627/2792/54429/50846/3361/6346/553/257313/134/9034/59350/3814/10800/2863/7481/1129/51083/2785/2783/2784/2829/1233/222545/6366/1241/2861/728/7474/183/10022/6373/57121/4922/5731/2865/7855/1132/1814/80835/6357/552/2925/8698/9934/2151/6869/6361/50840/2791/6343/2147/1813/50865/7976/10886/2837/10803/146/2913/3357/351/11251/8477/84432/3352/8484/2828/3062/1907/148/6351/6863/6752/135/1903/84539/6753/3577/594857/2918/5368/6754/6915/8862/10911/301/5032/2642/56670/150/2853/29933/6751/5020/4935/887/4829/186/53637/60675/51738/10563/5540/2864/1901/5733/256933/7200/5729/10850/624/2641/1392/2796/4852/4828/2786/680/50838/5473/4283/1910/6870/128674/11255/885/10874/83756/84634/147/6356/611/56477/387129/259286/3350/90226/129521/1234/151/57007/1238/3356/84109/7432/7472/9294/54331/4923/1128/283869/59345/4986/6374/5539/259287/2852/50836/1230/846/3358/4886/2919/1908/51764/94235/2695/259290/5196/3827/5173/2357/796/55970/2778/6352/57105/1133/140/3269/6348/886/2862/152/1906/6364/7253/80834/259292/5031/8620/2793/5030/5697/56413/3355/3351/6288/6372/1235/50834/259285/719/6363/2917/1268/50831/2359/1395/50839/347148/2846/5660/1815/1325/1232/4295/1902/551/154/50837/9002/1269/2915/3274/59340/5724/4887/1394/2790/718/623 356 Epstein.Barr_virus R-HSA-8856688 Golgi-to-ER retrograde transport 123/5894 133/10654 1.7710538563067295e-21 3.278779968188906e-20 1.1872438593524336e-20 11014/64837/11127/51807/53407/347688/3798/5861/10381/1780/5048/8655/84516/832/285643/55738/10112/636/64147/7846/51226/81027/11004/10749/81930/54732/51164/60561/113220/79861/3797/29127/55605/23299/377/1315/3796/5870/124602/11316/55614/89953/56992/8729/23423/10376/1314/10540/3835/147700/3833/378/9493/26286/26958/140735/10959/3831/84364/22820/84617/11258/1783/55850/9585/10382/93661/55860/830/3832/7277/10671/9554/23303/1639/8775/26153/81876/9183/1062/11015/146909/347733/662/90990/51143/23046/10383/24137/84790/84643/10945/5049/51594/22920/7280/829/22931/1778/55582/5321/9371/51014/23095/5050/1781/22930/25782/10121/6836/547/51560/10972/381/4905/3834/9276/55083/3799/375/221458/22818/372 123 Epstein.Barr_virus R-HSA-166166 MyD88-independent TLR4 cascade 96/5894 99/10654 2.190963536365576e-21 3.952161148290212e-20 1.4310746985167865e-20 8454/3725/9252/4790/7321/1848/4792/177/1432/929/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/23098/11035/8945/1326/5601/6283/5606/8737/8767/1849/29110/5594/28512/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/1846/3665/351/330/79155/7867/64127/5602/3656/7189/7311/9641/6416/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/7316/7335/4205/4793/3146/7322/329/466/23291/6288/2002/6285/5609/1385/5599/148022 96 Epstein.Barr_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 96/5894 99/10654 2.190963536365576e-21 3.952161148290212e-20 1.4310746985167865e-20 8454/3725/9252/4790/7321/1848/4792/177/1432/929/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/23098/11035/8945/1326/5601/6283/5606/8737/8767/1849/29110/5594/28512/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/1846/3665/351/330/79155/7867/64127/5602/3656/7189/7311/9641/6416/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/7316/7335/4205/4793/3146/7322/329/466/23291/6288/2002/6285/5609/1385/5599/148022 96 Epstein.Barr_virus R-HSA-156842 Eukaryotic Translation Elongation 91/5894 93/10654 2.6188738959600135e-21 4.664247559007265e-20 1.6889206737436993e-20 6158/6138/6227/6206/6234/6191/6128/6132/1917/6129/1915/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6171/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6166/1938/6136/6125/1937/6232/6160/1933/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/1936/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 91 Epstein.Barr_virus R-HSA-983169 Class I MHC mediated antigen processing & presentation 291/5894 371/10654 2.756371831968479e-21 4.8477689594745615e-20 1.7553736403588732e-20 8454/8773/5689/127544/11065/9666/55070/5682/8916/3107/7321/65264/9021/10484/8697/26235/9817/55176/9039/6478/811/143471/5705/10333/8452/5709/9978/5695/23304/567/54620/4734/7337/3693/84676/7704/3106/3093/5711/23327/51465/10616/5683/929/3309/25898/5699/7328/9632/7428/5702/22954/83737/51529/140461/10075/29945/79176/8924/56658/51434/6468/10425/25793/23295/3133/51666/90293/54461/29882/7334/55182/4591/3551/7332/5696/5691/9820/55658/7314/996/9354/5718/197131/8945/64410/10952/51320/5700/122706/5707/10477/148581/23198/10533/6892/51130/8517/6810/6477/7323/10517/1515/22872/4008/7096/84861/11059/27252/51444/26118/51433/9861/55905/10134/6502/5698/5692/5713/26190/79654/5710/9040/7324/5719/64682/51191/6233/3685/26091/6047/868/6396/127247/1535/5930/29116/26268/115290/51725/140459/23608/55585/64320/51132/1514/899/3135/23352/26224/4688/10293/653361/142678/246184/142686/151636/11146/255488/9616/91694/10802/10193/6890/821/81559/2209/144699/5706/200845/79876/26263/9554/8881/57630/29927/7317/80196/55958/84078/5714/26272/8651/64219/5688/55336/5687/26270/63893/5708/55008/2923/10422/695/90933/63891/9246/10393/5704/9870/9520/4012/25847/51343/7311/9871/7318/9320/26232/57520/5694/8673/3105/997/7325/140691/23643/57154/1147/140460/5684/6737/8065/5720/84708/7319/54850/79791/26046/991/84231/10273/7320/5690/223082/5717/9491/6500/26259/10197/7099/53339/7336/4615/64750/51619/23480/23376/6891/54778/7316/10213/114907/7335/222235/25831/7322/5715/9867/5701/9341/23291/5685/5686/114609/55521/55294/8453/80176/8139/126433/4689/26267/948/1520/5716/23194/55284/3134/80204/27338/7097/23014/1536/90678/5693/5721/51676/10427/642/4360 291 Epstein.Barr_virus R-HSA-6798695 Neutrophil degranulation 363/5894 480/10654 3.3864328413636294e-21 5.882359268887193e-20 2.1299980444704308e-20 5869/8773/7130/9798/1727/5689/8804/5777/5806/4893/9218/4790/5273/3240/960/7305/1823/1511/5657/57826/1915/4057/3107/203068/5175/5199/383/654364/8836/2268/5211/5908/1460/1265/29108/23385/10394/54509/6280/5788/535/10577/55276/10312/5709/10576/1509/5695/2896/4126/10562/8655/567/7133/154664/3106/3074/3417/3043/388698/1667/2548/2204/1432/11010/3920/5476/8904/5683/929/201294/2588/3482/4311/80142/2444/23200/5702/566/9961/51552/10075/56729/10487/6947/684/6709/6093/8826/9522/1794/4282/3608/2720/3312/3071/387263/2665/126014/51719/1654/967/2519/6037/5879/51316/2717/1992/5718/3303/58485/2934/80331/57554/64333/56954/161/6283/56888/3579/5707/2358/3848/823/427/353189/5594/4831/4680/6727/127829/7414/10533/55754/4257/51209/326624/847/3683/2517/25852/3934/8895/5834/9545/1315/102/116844/4069/12/9861/5870/410/411/28988/226/2821/978/55832/968/5713/2495/3614/3728/10043/4125/5478/5719/374395/5328/728/5580/23191/3685/302/1729/9145/5236/25797/6036/1535/2040/230/317/2990/401258/5663/7879/8907/671/2992/1508/28956/10450/7077/25801/1828/23352/7276/5284/4332/1938/8635/51125/51646/1650/3684/79888/387921/3163/54472/3577/79169/55860/1378/10549/2760/5864/4318/3958/79980/23317/5836/53917/6993/11240/10321/6616/5329/966/5611/84061/1116/527/6279/54918/4048/6286/5337/10092/5795/6793/197/140885/2171/3310/2352/1832/5708/55313/3615/820/51143/80301/4860/6386/10788/8993/6402/5473/3326/10857/55004/10097/3916/240/10383/387/178/10396/79930/5049/4317/51806/80184/1476/3304/2547/8673/10493/1075/53916/6282/114790/22931/1778/10694/2512/3837/10890/5036/8621/5005/327/11333/5315/8876/23197/1991/10120/6317/7520/5717/2919/5004/1118/25840/1512/2357/10213/4718/6278/5547/2799/5768/1471/9588/29952/7415/3146/79792/4353/5701/9342/6836/8649/3320/5686/388697/23593/391/175/25798/5873/1088/150372/23071/51411/5878/2683/11031/5646/948/1520/719/93100/47/5906/89777/81567/3687/124583/7097/5660/2212/1536/10970/3689/2207/5724/51382/2950/718 363 Epstein.Barr_virus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 79/5894 79/10654 3.8615718624069755e-21 6.480486205311705e-20 2.346579376329529e-20 2074/5982/7507/5431/5435/9978/5433/10980/57654/2965/5439/10987/2067/2967/6117/10714/91603/7314/6118/404672/3150/5438/3978/5985/10920/2068/5984/6233/7874/5424/8451/10450/5434/100534599/5436/7515/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/2071/51426/2873/7311/3980/8533/5983/5432/51138/56655/9318/6917/5440/902/27339/5430/57804/5441/2072/7316/64708/5426/5437/2033/2968/56949/9716/2073/5981/57461/1022/8178/50813 79 Epstein.Barr_virus R-HSA-202424 Downstream TCR signaling 95/5894 98/10654 3.868946988245794e-21 6.480486205311705e-20 2.346579376329529e-20 5295/8454/5689/4790/5682/5291/7321/143471/5705/3115/5709/5695/4792/3113/5711/3117/5683/5699/5702/3127/7334/3551/5696/5691/7314/5718/8945/3635/5290/5700/122706/5707/8767/23198/23118/10892/8517/3126/5970/9861/5588/5698/5692/5713/5710/916/5719/6233/3932/3120/5170/3123/5706/3122/920/8915/5714/5688/5687/5708/7189/5704/7311/3125/5694/997/1147/5684/5720/6885/3119/84433/5690/5717/9491/6500/10197/919/7316/10213/7335/50852/7322/5715/5701/23291/915/5685/917/5686/5728/5716/5296/5693/5721 95 Epstein.Barr_virus R-HSA-5620912 Anchoring of the basal body to the plasma membrane 95/5894 98/10654 3.868946988245794e-21 6.480486205311705e-20 2.346579376329529e-20 79867/7531/11190/203068/54801/85302/79441/5116/5048/22832/8655/9702/132320/7846/7840/11064/84902/5518/55835/23332/93323/1454/54806/91147/983/79959/10540/117177/57545/26005/54930/54820/23322/1453/9793/4218/11258/22981/8636/54903/80776/7532/55125/10382/121441/7277/9814/23354/146057/9738/1639/55722/4957/5566/7283/22919/27077/22994/4867/1069/5577/10383/5347/80184/22897/5108/261734/57787/10806/9657/1778/115106/22995/55559/10142/51134/95681/1781/80321/8766/79598/10121/347240/84131/3320/79600/10733/4751/80254/26123/9662/55142/8481/51259/55755 95 Epstein.Barr_virus R-HSA-5663220 RHO GTPases Activate Formins 128/5894 140/10654 3.936571554978117e-21 6.516183738652013e-20 2.3595054273800722e-20 55839/11130/71/6249/9735/5526/51807/9212/347688/388/147841/348995/10381/57122/1780/23122/3688/5048/57405/8655/23279/2491/7846/1060/81027/11004/1855/9184/5518/23332/25909/10726/81930/55746/5879/5515/79682/10403/79861/25936/1856/389/3619/64105/332/5528/6714/79902/3796/5519/81565/91687/11243/10376/23002/83540/1857/7514/54820/29984/1729/5217/6396/64946/9793/140735/220134/84617/4928/114793/5903/55055/80776/1783/401541/10382/79172/7277/79980/6232/5501/54821/9183/1062/699/347733/752/22919/5529/51143/998/286205/10383/5347/387/60/84790/84643/7280/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/6722/8379/23421/55920/79023/1781/4085/5216/81624/55166/51466/79003/5527/701/23380/57551 128 Epstein.Barr_virus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 85/5894 86/10654 4.188578849350702e-21 6.773943035674067e-20 2.452839882741367e-20 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 85 Epstein.Barr_virus R-HSA-453276 Regulation of mitotic cell cycle 85/5894 86/10654 4.188578849350702e-21 6.773943035674067e-20 2.452839882741367e-20 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 85 Epstein.Barr_virus R-HSA-877300 Interferon gamma signaling 90/5894 92/10654 4.6646622742883214e-21 7.458158886276895e-20 2.7005939482721862e-20 80263/5777/960/5770/3107/817/9021/3383/55223/3662/3115/4684/567/6672/3113/3106/3459/3717/3117/11074/5371/3133/117854/3127/4938/4261/818/115362/7412/85363/9830/163351/3126/2634/115361/10475/10437/10612/3458/3661/5580/81603/10107/4940/5781/3660/8554/3135/3665/3120/10379/2633/3123/23650/2209/8638/7706/23087/3122/3394/3663/6772/8651/3659/2635/5771/816/10346/3716/3125/7726/79097/53840/3105/3460/815/6737/23321/4281/3119/4502/51127/3664/4939/388646/7341/55128/3134/80128/5724 90 Epstein.Barr_virus R-HSA-69002 DNA Replication Pre-Initiation 84/5894 85/10654 7.532124277393809e-21 1.1907526807070887e-19 4.311706860152103e-20 5689/5682/143471/5705/5709/5422/1869/4174/5695/84515/4998/5711/10926/5683/990/5699/5702/55388/6117/5001/5558/5696/5691/7314/5718/6118/23594/5700/122706/5707/23198/5557/9861/5698/5692/5713/4175/5710/5719/6233/23649/4999/4172/5000/8318/54107/4173/5706/5714/51053/6119/5688/5687/5427/5708/81620/1870/5704/29935/23595/7311/5694/4176/56655/1017/5684/5720/8317/5690/5717/9491/10197/7316/10213/5426/4171/1871/5715/5701/5685/5686/5716/5693/5721 84 Epstein.Barr_virus R-HSA-69618 Mitotic Spindle Checkpoint 106/5894 112/10654 7.892627525467144e-21 1.2203216404760737e-19 4.418775850001269e-20 55839/11130/11065/6249/9735/7321/5526/8697/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/996/5515/79682/10403/25936/3619/64105/332/5528/51433/79902/3796/5519/81565/91687/119504/11243/7324/83540/64682/7514/54820/6396/64946/9793/140735/220134/4928/5903/246184/55055/80776/1783/401541/79172/79980/6232/8881/5501/54821/9183/1062/699/22919/5529/51143/10393/25906/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/55166/79003/5527/701/57551 106 Epstein.Barr_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 106/5894 112/10654 7.892627525467144e-21 1.2203216404760737e-19 4.418775850001269e-20 5295/8454/5689/5777/4893/4790/5579/5682/84876/143471/5705/5530/5709/5695/4792/5711/5683/2534/5699/5702/30011/2885/4794/3845/3265/3551/973/933/5696/5691/7314/6786/5718/8945/4773/5966/80228/5700/122706/5707/5336/23198/10892/8517/5970/9861/5698/5692/5713/5710/2280/5478/5719/6233/7409/118788/801/805/4772/4775/930/5706/7220/6850/8915/5714/5688/5687/4067/29760/5708/695/6654/5704/7311/5293/27071/5694/1147/5684/5720/6885/4690/640/84433/5690/5532/5717/9491/6500/10197/7316/10213/10768/4793/5715/5701/23291/5685/5686/5534/974/5716/808/5693/5721 106 Epstein.Barr_virus R-HSA-8878159 Transcriptional regulation by RUNX3 93/5894 96/10654 1.2050349228840462e-20 1.825995931949495e-19 6.61191808673591e-20 5689/6046/5682/182/5705/6097/6696/5709/5695/9759/10413/4609/4089/22938/5711/1387/7005/4088/5683/5699/5702/9794/6932/7040/3845/5696/5691/7314/5718/8463/51176/2648/5700/5707/55534/3280/84441/463/3683/865/83439/6714/9861/8850/5698/5692/5713/595/5710/7157/5719/6233/7004/1029/864/5706/10046/5714/6934/5688/5687/5708/5704/7311/5694/4851/3676/57154/5684/5720/2309/1499/10018/5690/5717/9491/10197/64750/7316/10213/1026/5715/5701/5685/5686/2033/861/5716/25937/3516/5693/5721/4193 93 Epstein.Barr_virus R-HSA-2990846 SUMOylation 163/5894 188/10654 1.206948270584954e-20 1.825995931949495e-19 6.61191808673591e-20 1912/10054/23165/7068/7486/9112/6045/9212/80012/10274/348995/6613/57122/7181/23511/4929/28996/54780/4792/3190/9759/9612/8856/1911/9994/6790/6672/23279/1387/1789/23225/10055/23512/165918/57332/7022/7067/7428/1107/5371/8924/4152/672/115426/9972/10499/6612/5914/8021/6117/11315/55746/7421/4286/10062/79677/7150/6670/83746/3622/1788/51564/51588/7518/3619/7153/51602/2516/8517/332/10762/5465/1655/5970/2099/79902/2494/9656/9883/84733/3066/7157/668/7158/10155/9063/7155/7690/6396/129401/7703/4791/6015/8554/7020/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/493861/5111/4927/10521/1616/2908/8243/142/9971/1069/8086/7329/367/25942/9641/648/6095/23468/5905/81929/5893/29843/1487/55143/9631/5468/7021/8204/3090/79023/23636/10735/3183/4306/53371/6996/23137/9688/7341/10401/59343/2033/9126/3065/23314/6256/5987/7376/6294/8648/6304/8480/10891/7508/4193/205564 163 Epstein.Barr_virus R-HSA-8876198 RAB GEFs exchange GTP for GDP on RABs 88/5894 90/10654 1.478513864800867e-20 2.2130521359306593e-19 8.013445806983422e-20 5869/163486/116442/126003/7531/22878/1122/54453/10981/5861/163259/5866/23011/9610/60684/3257/414918/51762/51552/126432/201475/5874/79961/2665/79090/22898/58485/5868/81846/51622/84079/51209/5872/9827/80006/5870/8408/9909/10000/51112/117177/83696/1121/23682/27095/6399/7109/4218/7879/2664/201627/27342/23258/5864/10260/57679/81876/259173/6305/51693/8567/208/79890/22879/54734/57589/84315/22931/51399/10890/207/122553/79958/57706/22930/55667/26130/27147/25782/9367/51560/11021/5873/5878/11031/338382/89781/160518 88 Epstein.Barr_virus R-HSA-1236974 ER-Phagosome pathway 82/5894 83/10654 2.4341173488980616e-20 3.605055905157445e-19 1.3053881405724782e-19 8773/5689/5682/3107/55176/811/143471/5705/10333/5709/5695/567/3106/5711/5683/929/5699/5702/3133/3551/5696/5691/7314/5718/10952/5700/122706/5707/23198/6892/8517/6810/7096/9861/5698/5692/5713/5710/5719/6233/3135/6890/5706/9554/29927/5714/5688/5687/5708/2923/695/5704/7311/5694/8673/3105/23643/1147/5684/5720/5690/5717/9491/10197/7099/4615/23480/6891/7316/10213/5715/5701/9341/5685/5686/114609/948/5716/3134/7097/5693/5721 82 Epstein.Barr_virus R-HSA-156902 Peptide chain elongation 87/5894 89/10654 2.6309979056192668e-20 3.856056305423238e-19 1.396275204297944e-19 6158/6138/6227/6206/6234/6191/6128/6132/6129/1915/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6171/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6166/1938/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 87 Epstein.Barr_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 158/5894 182/10654 3.586429874260388e-20 5.202171992870481e-19 1.8837027228887981e-19 1912/23165/7068/7486/9112/6045/9212/80012/10274/348995/6613/57122/7181/23511/4929/28996/54780/4792/3190/9759/9612/8856/1911/9994/6790/6672/23279/1387/1789/23225/23512/165918/57332/7022/7067/7428/1107/5371/8924/4152/672/115426/9972/10499/6612/5914/8021/6117/11315/55746/7421/4286/10062/79677/7150/6670/83746/3622/1788/51564/51588/7518/3619/7153/51602/2516/8517/332/10762/5465/1655/5970/2099/79902/2494/9656/9883/84733/3066/7157/668/7158/10155/9063/7155/7690/6396/129401/7703/4791/6015/8554/7020/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/493861/5111/4927/10521/1616/2908/8243/142/9971/1069/8086/7329/367/25942/9641/648/6095/23468/5905/81929/5893/1487/55143/9631/5468/7021/8204/3090/79023/23636/10735/3183/4306/53371/6996/23137/9688/7341/10401/2033/9126/3065/23314/6256/5987/7376/6294/8648/6304/8480/10891/7508/4193 158 Epstein.Barr_virus R-HSA-1236975 Antigen processing-Cross presentation 95/5894 99/10654 4.372105397040199e-20 6.216857020556241e-19 2.251119438857757e-19 8773/5689/5682/3107/55176/811/143471/5705/10333/5709/5695/567/3693/3106/5711/5683/929/5699/5702/3133/3551/5696/5691/7314/5718/10952/5700/122706/5707/23198/6892/8517/6810/1515/7096/9861/5698/5692/5713/5710/5719/6233/3685/1535/1514/3135/4688/653361/6890/2209/5706/9554/29927/5714/5688/5687/5708/2923/695/5704/4012/7311/5694/8673/3105/23643/1147/5684/5720/5690/5717/9491/10197/7099/4615/23480/6891/7316/10213/5715/5701/9341/5685/5686/114609/4689/948/1520/5716/3134/7097/1536/5693/5721/4360 95 Epstein.Barr_virus R-HSA-9013694 Signaling by NOTCH4 81/5894 82/10654 4.37433436414405e-20 6.216857020556241e-19 2.251119438857757e-19 8454/5689/5682/182/23385/5705/5709/9978/5695/22938/5711/1387/4088/5683/5699/4853/5702/9794/388585/5696/5691/7314/5718/2648/5700/5707/55534/3280/84441/7534/102/5664/9861/8850/5698/5692/5713/5710/5719/6233/2324/5663/5706/10460/10046/5714/5688/5687/5708/59/4855/5704/83464/23493/7311/55851/51107/5694/4851/5684/5720/23462/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/2033/55294/5716/54567/3516/5693/5721 81 Epstein.Barr_virus R-HSA-72764 Eukaryotic Translation Termination 90/5894 93/10654 6.603831362413726e-20 9.291590726916113e-19 3.36447829411394e-19 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/51504/6171/6147/6222/2935/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/2107/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/23708/9045/6187/6168/6157/6137/6144/9349/4736/327/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 90 Epstein.Barr_virus R-HSA-2500257 Resolution of Sister Chromatid Cohesion 116/5894 126/10654 6.797367635297461e-20 9.46920422065696e-19 3.428792011968704e-19 55839/11130/6249/9735/5526/51807/9212/347688/10274/147841/348995/10381/57122/1780/23122/5048/57405/8655/23279/2491/7846/1060/81027/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/79861/25936/55869/3619/64105/332/5528/983/79902/3796/5519/81565/91687/11243/10376/83540/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/55055/80776/1783/401541/10382/79172/7277/9133/79980/6232/23047/5885/891/5501/54821/9183/1062/699/347733/22919/8243/5529/51143/10383/5347/84790/84643/7280/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23244/23421/55920/79023/10735/1781/4085/55166/79003/9126/5527/701/57551 116 Epstein.Barr_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 94/5894 98/10654 7.63997816957699e-20 1.043635852873284e-18 3.7789978886819244e-19 8454/3725/9252/4790/1848/10333/4792/59307/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/11213/8767/1849/5594/4214/28512/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/653509/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/7335/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/57161 94 Epstein.Barr_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 94/5894 98/10654 7.63997816957699e-20 1.043635852873284e-18 3.7789978886819244e-19 8454/3725/9252/4790/1848/10333/4792/59307/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/11213/8767/1849/5594/4214/28512/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/653509/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/7335/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/57161 94 Epstein.Barr_virus R-HSA-73894 DNA Repair 263/5894 334/10654 9.17192283563815e-20 1.240855329782969e-18 4.493128190737716e-19 2237/4436/221120/83990/151987/4350/5892/9156/2074/1763/7486/4913/56852/10445/5982/8505/11200/472/6613/7507/80198/3981/5431/5435/2140/9978/5433/85015/26277/10980/64421/4683/57654/2965/25898/165918/84126/5439/10987/8900/8924/57599/2067/672/2967/6612/6117/7334/10973/10714/55666/54386/348654/91603/83695/4437/55183/7314/51514/22909/7014/6118/2176/25/5888/322/328/83444/51588/79068/7518/51720/63967/404672/9557/5531/9636/3150/86/5438/3978/11201/116028/2070/890/197342/1643/7517/9656/84464/51455/29844/2177/5985/10920/29089/2068/7157/5984/4595/4255/54891/6233/7158/6047/93973/55247/8607/7874/5884/5810/5424/2188/5886/57697/8451/8554/10450/8467/80010/124739/3838/5434/7516/100534599/5436/2956/7515/54107/7013/4292/7706/51567/580/11073/5591/8450/5423/4331/5425/641/5111/2966/6119/83932/3364/22976/10524/5427/144715/1161/5889/55775/1642/5429/142/125476/1111/2071/9682/55215/10721/1069/7329/9246/79728/51426/2873/146956/7311/7318/4968/23030/3980/60/5536/8533/5983/2175/10038/2547/5432/51138/7528/56655/9318/11284/51750/1017/54962/25913/6917/5440/5893/2178/902/84164/5883/27339/5430/10111/57804/7320/7520/675/51548/545/5441/7336/2072/29086/54778/7316/6996/64708/8314/79008/5426/9100/10635/10459/7415/5395/283899/7341/4798/5437/51008/79913/10401/9937/54617/65057/2033/8914/7398/23514/64858/2968/5932/8930/2138/9025/2189/55120/2187/79184/56949/7156/5890/5887/9716/2073/5599/5981/57461/1022/2139/8178/50813/5980/7508/7374 263 Epstein.Barr_virus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 79/5894 80/10654 1.411765111663812e-19 1.8917652496295083e-18 6.850068311230926e-19 8454/5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 79 Epstein.Barr_virus R-HSA-2262752 Cellular responses to stress 358/5894 479/10654 1.991235679604462e-19 2.6430835860410167e-18 9.570586583203172e-19 1912/23165/5689/3725/6782/9134/2077/11065/573/4790/5682/64344/7531/1915/11133/7321/51807/817/6045/8697/9530/347688/27327/80012/7295/5925/3091/348995/143471/472/10381/57122/5705/79813/9681/3576/3313/1780/7001/23511/10312/5709/9978/2114/1869/5695/3305/8655/84516/1911/832/26277/23279/4194/1031/5711/5928/1432/1387/4683/7846/259217/23225/5683/3309/23512/57332/5699/126374/7428/5702/192669/9531/81027/8900/51529/4001/29945/8091/8131/2056/51434/2475/1032/3306/27000/1030/6196/9972/23411/8021/4343/6117/10587/6197/29882/3312/4217/54386/3569/55746/5696/5691/7296/7314/51164/996/51182/5718/818/3303/7014/6118/5601/79861/5606/7027/5700/122706/5707/2146/9550/2936/9114/5594/3308/84335/23198/898/10049/10013/27244/3337/10762/847/7323/890/5970/9261/6667/51433/9861/79902/5598/9883/2932/84733/9973/529/5698/5692/5713/2877/119504/10376/6195/5710/3301/10540/7157/7324/5719/64682/6233/2353/7029/8726/6396/1535/129401/5600/523/201163/26523/528/405/5608/3297/57521/140735/768/6015/28956/84617/4928/4688/1019/5903/83667/55706/7175/653361/5241/11258/9448/246184/112399/1029/1783/389541/25828/8535/84962/10382/93661/5931/10294/55860/830/7013/7277/1051/1410/50488/5706/10671/8881/527/6774/1639/5714/4927/7867/64223/6119/26353/3552/10370/10524/5688/57805/5687/3310/2908/347733/5708/5602/7266/25824/6009/51143/816/6648/8086/10393/1870/5704/3326/55004/51343/7311/367/25906/3397/2034/79400/57634/10383/84790/55662/648/5694/3304/23466/3456/2113/6416/10641/7280/10728/829/23523/5595/1778/1017/815/25913/81929/5684/5720/9631/3159/7290/10111/7422/5690/57690/5717/1027/9491/545/79023/23636/10197/192670/10808/3490/8550/29855/4306/1781/7316/10213/10935/53371/1026/9532/54205/2289/9588/9688/10121/7415/1871/6647/8994/7322/5715/5701/84219/112398/5685/8649/3320/65057/5686/2033/1021/6767/25842/8453/23135/10963/22824/57600/23112/5609/10542/4689/5716/9529/5599/54583/5052/1536/96459/5693/5721/55466/2288/5034/8480/10919/51382/318/4193/2950/23043 358 Epstein.Barr_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 96/5894 101/10654 2.3065024410239693e-19 3.0329429294586216e-18 1.098226445111265e-18 8454/5689/4790/5682/7321/9039/29108/143471/5705/5530/5709/5695/4792/5711/5683/5699/5702/64170/7334/3551/5696/5691/7314/257397/5718/8945/4773/5700/122706/5707/5336/23198/23118/10892/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/801/4791/805/5170/4772/4775/5706/64581/6850/8915/5714/5688/5687/5708/7189/5704/7311/5971/5694/997/1147/5684/5720/6885/84433/5690/3553/5532/5717/9491/6500/10197/7316/10213/7335/10768/7322/5715/5701/23291/5685/5686/5534/5716/808/5693/5721 96 Epstein.Barr_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 83/5894 85/10654 2.629430911363759e-19 3.3632811748080083e-18 1.2178416852632147e-18 8454/3725/9252/4790/1848/4792/177/1432/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/8767/1849/5594/4214/28512/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/81793/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/28511/5595/5516/1147/1845/6885/5604/10392/6500/4615/7100/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 83 Epstein.Barr_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 83/5894 85/10654 2.629430911363759e-19 3.3632811748080083e-18 1.2178416852632147e-18 8454/3725/9252/4790/1848/4792/177/1432/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/8767/1849/5594/4214/28512/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/81793/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/28511/5595/5516/1147/1845/6885/5604/10392/6500/4615/7100/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 83 Epstein.Barr_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 83/5894 85/10654 2.629430911363759e-19 3.3632811748080083e-18 1.2178416852632147e-18 8454/3725/9252/4790/1848/4792/177/1432/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/8767/1849/5594/4214/28512/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/81793/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/28511/5595/5516/1147/1845/6885/5604/10392/6500/4615/7100/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 83 Epstein.Barr_virus R-HSA-199418 Negative regulation of the PI3K/AKT network 103/5894 110/10654 2.900281521075573e-19 3.676302792930929e-18 1.3311865871982714e-18 5295/374/3643/2250/23035/5291/5526/3082/941/2064/145957/2534/9965/2264/3630/3654/9542/2885/8396/51135/8660/5518/2252/2253/5879/5515/23396/1839/5290/3667/6801/8823/90865/2065/3815/5594/2069/8074/79837/57761/2260/5528/2249/6714/2099/2248/5519/2247/5880/10000/7409/2246/2251/3932/118788/8394/5781/940/23239/930/2263/4233/8503/5159/29851/3084/5529/7189/208/10718/5293/1956/2549/5595/3556/5516/685/5305/5525/8870/207/8817/4615/2100/2254/152831/1950/50852/26281/10818/2261/2255/391/5728/2066/27006/942/5527/9173/5155/4254/5296/5156 103 Epstein.Barr_virus R-HSA-2132295 MHC class II antigen presentation 113/5894 123/10654 3.2100932818602594e-19 4.032679685336951e-18 1.4602304026507193e-18 64837/162/11127/51807/10484/1174/347688/3798/1785/10381/1780/3115/1509/8655/84516/3109/832/285643/3113/10112/972/7846/5476/3117/9632/81027/6456/11004/3112/163/1759/3127/81930/51164/161/79861/3797/10053/29127/3126/1515/22872/3111/3796/10437/89953/56992/83547/10376/10540/3835/147700/1213/1211/9493/6396/1175/7879/140735/8907/1508/1514/3831/3120/1173/84617/11258/6712/1783/10382/10802/93661/821/55860/830/3123/3832/7277/160/10671/3122/1639/26153/1062/347733/51143/9871/10383/24137/84790/84643/8905/3125/22920/1075/7280/829/1778/114876/164/9371/3119/10120/130340/1512/1781/1513/5641/10121/1520/3799/375/10427 113 Epstein.Barr_virus R-HSA-162599 Late Phase of HIV Life Cycle 125/5894 139/10654 4.0061498946439746e-19 4.988188408640772e-18 1.8062194215255556e-18 6884/23165/6875/51652/27243/6874/348995/57122/55048/5431/23511/5435/5433/2960/51271/23279/23327/29082/23225/2965/27183/5439/6873/9972/6881/2967/51616/8021/11198/904/51497/55746/92421/7314/137492/25978/51160/2959/404672/10015/91782/5438/10762/79720/51534/4836/9397/79902/9883/89853/83860/51510/2068/5902/5478/6233/7514/1025/6396/129401/6883/7936/6829/2957/25920/4928/2963/5434/5903/55706/7175/79643/5436/6878/4331/4927/8148/2966/2962/54457/8812/128866/905/2071/5901/8086/7311/93343/6880/6908/7251/1104/6882/2961/5432/22916/155382/6877/5905/6917/81929/5440/902/9631/5430/5045/6749/79023/5441/23636/4686/7316/6872/53371/9688/8731/6879/9525/2958/5437/2968/138474/1022/8178/8480 125 Epstein.Barr_virus R-HSA-192823 Viral mRNA Translation 86/5894 89/10654 6.342711065461248e-19 7.828240762371908e-18 2.8346003284240478e-18 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6171/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/5611/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 86 Epstein.Barr_virus R-HSA-4420097 VEGFA-VEGFR2 Pathway 94/5894 99/10654 6.907598629326857e-19 8.451296757793817e-18 3.0602084545484653e-18 5295/4893/857/5335/71/5579/5291/5578/1432/2534/9475/3690/5603/2475/6093/8440/9564/3845/3265/3071/8877/5062/5829/5879/26999/5290/5567/10006/57761/5921/1500/9261/6714/10810/10000/3728/7410/5580/7409/23191/3685/3791/1535/5600/6300/801/10787/253260/805/5170/4688/5590/653361/6461/5747/5568/3315/10451/1793/10152/7867/64223/5566/1003/10163/55845/5063/998/208/79109/2185/387/60/5058/63916/25759/558/1495/1499/4690/207/7422/10458/9047/10768/8936/3320/4846/1398/4689/9844/5296/808/1536 94 Epstein.Barr_virus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 97/5894 103/10654 1.0437694139571475e-18 1.2660203150325055e-17 4.584250420646637e-18 5295/374/3643/2250/5291/5526/3082/941/2064/145957/2534/9965/2264/3630/3654/9542/2885/8396/51135/8660/5518/2252/2253/5879/5515/23396/1839/5290/3667/6801/8823/90865/2065/3815/5594/2069/8074/79837/2260/5528/2249/6714/2099/2248/5519/2247/5880/7409/2246/2251/3932/118788/8394/5781/940/930/2263/4233/8503/5159/29851/3084/5529/7189/10718/5293/1956/2549/5595/3556/5516/685/5305/5525/8870/207/8817/4615/2100/2254/152831/1950/50852/26281/10818/2261/2255/391/2066/27006/942/5527/9173/5155/4254/5296/5156 97 Epstein.Barr_virus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 85/5894 88/10654 1.1153496986153559e-18 1.3412795093605177e-17 4.8567634199715e-18 8454/7531/11190/203068/54801/79441/5116/5048/8655/6790/9702/7846/7840/11064/5518/55835/23332/93323/7314/8945/4659/1454/983/79959/10540/6233/54930/54820/1453/9793/4218/5500/11258/22981/8636/7532/84962/55125/10382/121441/7277/9133/9814/23354/891/9738/1639/55722/4957/5566/7283/22919/22994/79866/1069/5577/7311/10133/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/6500/1781/7316/80321/10121/84131/23291/3320/10733/4751/80254/9662/55142/8481/55755 85 Epstein.Barr_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 89/5894 93/10654 1.235364960085137e-18 1.4606373939830152e-17 5.288957458480374e-18 8454/3725/9252/4790/1848/4792/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/6283/5606/8767/1849/5594/4214/28512/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/1846/3665/351/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161/148022 89 Epstein.Barr_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 89/5894 93/10654 1.235364960085137e-18 1.4606373939830152e-17 5.288957458480374e-18 8454/3725/9252/4790/1848/4792/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/6283/5606/8767/1849/5594/4214/28512/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/1846/3665/351/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161/148022 89 Epstein.Barr_virus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 75/5894 76/10654 1.4664146362548478e-18 1.6983136314970593e-17 6.149581398605294e-18 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 75 Epstein.Barr_virus R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 80/5894 82/10654 1.472596041525524e-18 1.6983136314970593e-17 6.149581398605294e-18 114791/10844/440145/7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/1454/983/79959/80097/10540/85378/54930/54820/1453/27229/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/728642/9738/1639/55722/4957/5566/7283/22919/984/10426/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 80 Epstein.Barr_virus R-HSA-380287 Centrosome maturation 80/5894 82/10654 1.472596041525524e-18 1.6983136314970593e-17 6.149581398605294e-18 114791/10844/440145/7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/1454/983/79959/80097/10540/85378/54930/54820/1453/27229/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/728642/9738/1639/55722/4957/5566/7283/22919/984/10426/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 80 Epstein.Barr_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 92/5894 97/10654 2.0638015160842812e-18 2.360787587911044e-17 8.548394812022183e-18 8454/3725/9252/4790/1848/4792/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/6283/5606/8767/1849/5594/4214/28512/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/30849/5608/4791/1846/3665/351/8411/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/7335/4205/5289/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161/148022 92 Epstein.Barr_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 88/5894 92/10654 2.152023774697752e-18 2.4418527830643044e-17 8.841931298418607e-18 8454/3725/9252/4790/1848/4792/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/6283/5606/8767/1849/5594/4214/28512/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/1846/351/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161/148022 88 Epstein.Barr_virus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 74/5894 75/10654 2.6309884782233845e-18 2.9614406310882415e-17 1.072335514492731e-17 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 74 Epstein.Barr_virus R-HSA-2219528 PI3K/AKT Signaling in Cancer 95/5894 101/10654 3.0690923174316064e-18 3.427153087798627e-17 1.2409696588445258e-17 5295/2308/374/2250/5291/3082/941/2064/145957/2534/9965/2264/9542/2885/2475/8660/2252/2253/5879/1839/5290/3667/6801/8823/2065/3815/2069/84335/8074/7249/2260/2249/6714/2099/2248/2932/2247/5880/10000/7409/2246/2251/3932/2931/118788/5781/940/253260/5170/572/4303/930/6199/2263/4233/64223/8503/5159/29851/3084/208/10718/79109/5293/1956/2549/1147/685/2309/842/207/1027/8817/2100/2254/152831/1950/1026/50852/26281/10818/2261/2255/3164/391/5728/2066/27006/942/1385/5155/4254/5296/5156/4193 95 Epstein.Barr_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 82/5894 85/10654 6.0478344977747894e-18 6.700238691629235e-17 2.4261515929738897e-17 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/91768/5934/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/7029/1163/1019/5706/286826/4331/5714/5688/5687/5708/1874/208/5704/55957/51343/7311/5694/1017/5684/994/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5715/5701/5685/5686/5716/1022/5693/5721 82 Epstein.Barr_virus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72/5894 73/10654 8.462845353700948e-18 9.230405746245918e-17 3.3423232567860126e-17 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/5716/701/5693/5721 72 Epstein.Barr_virus R-HSA-1980143 Signaling by NOTCH1 72/5894 73/10654 8.462845353700948e-18 9.230405746245918e-17 3.3423232567860126e-17 8454/79718/892/113878/182/3091/23385/9978/9759/9612/4609/22938/1387/6907/408/83737/6868/9794/57534/388585/28514/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/7091/8650/1272/102/5664/8850/3066/6233/7089/5663/7090/142678/23220/409/10046/1024/10014/26508/9148/7088/83464/23493/7311/55851/51107/4851/8841/23462/6500/7316/9611/54492/2033/55294/3065/92737/1840/54567/3516 72 Epstein.Barr_virus R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic 93/5894 99/10654 8.999871408122304e-18 9.740630054790832e-17 3.527075110551575e-17 11014/64837/11127/51807/53407/347688/3798/5861/10381/285643/55738/10112/64147/7846/51226/81027/11004/10749/81930/54732/60561/113220/79861/3797/29127/55605/377/1315/3796/124602/11316/55614/89953/56992/8729/23423/10376/1314/3835/147700/3833/378/9493/26286/26958/10959/3831/84364/22820/84617/55850/9585/10382/3832/7277/9554/23303/8775/26153/81876/9183/1062/11015/146909/347733/662/90990/23046/10383/24137/84790/84643/10945/51594/22920/7280/55582/9371/51014/23095/6836/547/10972/381/4905/3834/9276/55083/3799/375/221458/22818/372 93 Epstein.Barr_virus R-HSA-6782135 Dual incision in TC-NER 66/5894 66/10654 9.124459829585709e-18 9.80008777116572e-17 3.548604706725177e-17 2074/5982/7507/5431/5435/9978/5433/57654/2965/5439/2067/2967/6117/10714/91603/7314/6118/404672/3150/5438/5985/2068/5984/6233/7874/5424/8451/10450/5434/100534599/5436/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/2071/51426/7311/5983/5432/56655/6917/5440/902/27339/5430/57804/5441/2072/7316/5426/5437/2033/2968/56949/9716/2073/5981/57461/1022 66 Epstein.Barr_virus R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 89/5894 94/10654 1.0608667871184484e-17 1.122928804297726e-16 4.066117093331083e-17 114791/10844/440145/7531/11190/203068/54801/51807/347688/79441/10381/5116/5048/8655/9702/7846/7840/11064/81027/5518/55835/29922/23332/93323/79861/1454/983/79959/80097/10376/10540/85378/54930/54820/1453/27229/9793/84617/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/9738/1639/55722/4957/5566/7283/347733/22919/10426/22994/1069/5577/10383/5347/84790/80184/22897/5108/7280/10806/1778/115106/4926/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 89 Epstein.Barr_virus R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 81/5894 84/10654 1.0614749891371539e-17 1.122928804297726e-16 4.066117093331083e-17 7124/1052/84498/4790/79718/9441/892/5469/9612/1387/6907/84246/4023/55588/10499/23054/7040/85441/9282/23097/96764/51129/7471/3952/5465/10025/5970/6604/80205/9439/896/9370/1879/9412/9969/54797/5105/55090/1019/9440/6721/9862/1051/9442/1050/1024/9314/9968/5346/10001/23389/9443/9477/2167/51586/400569/6517/80306/8841/5468/29079/90390/6720/6837/688/9611/81857/2033/9967/7026/6256/51003/10498/948/112950/27332/8202/8648/1959/10891/219541 81 Epstein.Barr_virus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 71/5894 72/10654 1.5172167930166455e-17 1.569650020422368e-16 5.683691391796103e-17 5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 71 Epstein.Barr_virus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 71/5894 72/10654 1.5172167930166455e-17 1.569650020422368e-16 5.683691391796103e-17 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 71 Epstein.Barr_virus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 71/5894 72/10654 1.5172167930166455e-17 1.569650020422368e-16 5.683691391796103e-17 5689/9134/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/990/5699/5702/8900/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/898/890/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/1017/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 71 Epstein.Barr_virus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 65/5894 65/10654 1.6575554149165025e-17 1.7023215100638825e-16 6.164093897960715e-17 2074/5982/5431/5435/9978/5433/57654/2965/5439/2967/6117/10714/91603/7314/6118/404672/3150/5438/3978/5985/2068/5984/6233/7874/5424/8451/10450/5434/100534599/5436/7515/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/2071/51426/7311/3980/5983/5432/56655/6917/5440/902/27339/5430/57804/5441/7316/5426/5437/2033/2968/56949/9716/5981/57461/1022 65 Epstein.Barr_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 80/5894 83/10654 1.862099088711148e-17 1.884872962457975e-16 6.825111389141958e-17 8454/5689/4893/4790/5579/5682/143471/5705/5530/5709/5695/4792/5711/5683/5699/5702/4794/3845/3265/3551/5696/5691/7314/5718/8945/4773/5966/5700/122706/5707/23198/10892/8517/5970/9861/5698/5692/5713/5710/2280/5478/5719/6233/801/805/4772/4775/5706/8915/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/84433/5690/5532/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5534/5716/808/5693/5721 80 Epstein.Barr_virus R-HSA-69202 Cyclin E associated events during G1/S transition 80/5894 83/10654 1.862099088711148e-17 1.884872962457975e-16 6.825111389141958e-17 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/91768/5934/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/7029/1163/1019/5706/286826/4331/5714/5688/5687/5708/1874/208/5704/55957/7311/5694/1017/5684/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5715/5701/5685/5686/5716/1022/5693/5721 80 Epstein.Barr_virus R-HSA-6802957 Oncogenic MAPK signaling 70/5894 71/10654 2.7193453550957773e-17 2.7135595139147227e-16 9.825779409229981e-17 4893/71/817/5908/55109/54845/8546/22866/5605/5037/3717/10827/2244/3690/408/4296/5894/8826/1185/4140/3845/3265/4763/818/8805/55750/8844/7094/5594/7414/10533/23164/57085/6714/9061/2335/1445/2266/2243/369/801/57670/805/283455/3674/409/673/8315/816/56829/7450/60/9444/7529/5595/4000/27044/815/22906/8087/5604/10018/10142/54518/80853/10256/5906/808/9715/5245 70 Epstein.Barr_virus R-HSA-68949 Orc1 removal from chromatin 70/5894 71/10654 2.7193453550957773e-17 2.7135595139147227e-16 9.825779409229981e-17 8454/5689/5682/143471/5705/5709/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/890/9861/6502/5698/5692/5713/4175/5710/5719/6233/4999/4172/5000/4173/5706/5714/5688/5687/5708/81620/5704/23595/7311/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 70 Epstein.Barr_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 79/5894 82/10654 3.264935103852188e-17 3.2350448529014286e-16 1.1714074056815856e-16 8454/5689/5682/5526/1452/143471/5705/5709/9978/5695/5711/5683/324/5699/8312/5702/6932/5518/5696/5691/7314/5515/5718/51176/8945/5700/122706/5707/23198/5528/7091/83439/9861/5519/2932/5698/5692/5713/5710/5719/6233/7089/7090/5706/23401/5714/6934/5688/5687/5708/5529/7088/5704/7311/5694/5516/5684/5720/1487/1499/5525/139285/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/3065/5527/1488/5716/5693/5721 79 Epstein.Barr_virus R-HSA-8953897 Cellular responses to external stimuli 361/5894 493/10654 3.8618034899631824e-17 3.79969056669804e-16 1.3758652109990284e-16 1912/23165/5689/3725/6782/9134/2077/11065/573/4790/5682/64344/7531/1915/11133/7321/51807/817/6045/8697/9530/347688/27327/80012/7295/5925/3091/348995/143471/472/10381/57122/5705/79813/9681/3576/3313/1780/7001/23511/10312/5709/9978/2114/1869/5695/3305/8655/84516/1911/832/26277/23279/4194/1031/5711/5928/1432/1387/4683/7846/259217/23225/5683/3309/23512/57332/5699/126374/7428/5702/192669/9531/81027/8900/51529/4001/29945/8091/8131/2056/51434/2475/1032/3306/27000/1030/6196/9972/23411/8021/4343/6117/10587/6197/29882/3312/4217/54386/3569/55746/5696/5691/7296/7314/51164/996/51182/5718/818/3303/7014/6118/5601/79861/5606/7027/5700/122706/5707/2146/9550/2936/9114/5594/3308/84335/23198/898/10049/10013/27244/3337/10762/847/7323/890/5970/9261/6667/51433/9861/79902/5598/9883/2932/84733/9973/529/5698/5692/5713/2877/119504/10376/6195/5710/3301/10540/7157/7324/5719/64682/6233/2353/7029/8726/6396/1535/129401/5600/523/201163/26523/528/405/5608/3297/57521/140735/768/6015/28956/84617/4928/4688/1019/5903/83667/55706/7175/653361/5241/11258/9448/246184/112399/1029/1783/389541/25828/8535/84962/10382/93661/5931/10294/55860/830/7013/7277/1051/1410/50488/5706/10671/8881/527/6774/1639/5714/4927/7867/64223/6119/26353/3552/10370/10524/5688/57805/5687/3310/2908/347733/5708/5602/7266/25824/6009/51143/816/6648/8086/10393/1870/5704/3326/55004/51343/7311/367/25906/3397/2034/79400/57634/10383/84790/55662/648/5694/3304/23466/3456/2113/6416/10641/7280/10728/829/23523/5595/1778/1017/815/25913/81929/5684/5720/9631/3159/7290/10111/4502/7422/5690/57690/5717/1027/9491/545/79023/23636/10197/192670/10808/3490/8550/29855/4306/1781/7316/10213/4501/10935/53371/1026/9532/54205/2289/9588/9688/10121/7415/1871/6647/8994/7322/5715/5701/84219/112398/5685/8649/3320/65057/5686/2033/1021/6767/25842/8453/23135/10963/22824/57600/23112/5609/10542/4689/5716/9529/4520/5599/54583/5052/1536/96459/5693/5721/55466/2288/5034/8480/10919/51382/318/4193/2950/23043 361 Epstein.Barr_virus R-HSA-141424 Amplification of signal from the kinetochores 90/5894 96/10654 4.495422409745279e-17 4.362109883111454e-16 1.579516839431372e-16 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/79902/3796/5519/81565/91687/11243/83540/7514/54820/6396/64946/9793/140735/220134/4928/5903/55055/80776/1783/401541/79172/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/55166/79003/5527/701/57551 90 Epstein.Barr_virus R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 90/5894 96/10654 4.495422409745279e-17 4.362109883111454e-16 1.579516839431372e-16 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/79902/3796/5519/81565/91687/11243/83540/7514/54820/6396/64946/9793/140735/220134/4928/5903/55055/80776/1783/401541/79172/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/55166/79003/5527/701/57551 90 Epstein.Barr_virus R-HSA-909733 Interferon alpha/beta signaling 68/5894 69/10654 8.728612098334141e-17 8.411751522161737e-16 3.0458891532759365e-16 3443/5777/3442/5770/3107/9021/11274/3662/3106/4599/684/3133/3429/91543/4938/5696/3445/10410/9636/2634/3444/103/3434/3433/3451/3448/3661/3439/10581/3452/4940/3437/6773/7297/5781/3430/3660/3446/3135/3665/10379/3455/4600/8638/3394/3663/6772/8651/3659/25939/3440/3454/3716/3456/3105/3441/51447/54739/2537/3449/8519/3664/6041/1958/4939/6059/3669/3134 68 Epstein.Barr_virus R-HSA-9007101 Rab regulation of trafficking 111/5894 124/10654 9.282794821871061e-17 8.884960758076587e-16 3.2172378759653374e-16 5869/163486/116442/126003/7531/22878/1122/54453/57533/10981/83874/5861/163259/5866/23011/9610/60684/3257/414918/51762/51552/9230/126432/201475/5874/79961/2665/79090/22898/125058/58485/5868/81846/51622/7249/23637/26000/84079/51209/5872/9827/80006/5870/8408/9909/10000/64786/51112/117177/83696/1121/23682/27095/6399/7109/4218/7879/2664/201627/26088/27342/23258/9363/5864/10260/382/57679/81876/9135/259173/6305/51693/8567/208/5867/79890/22879/10133/54734/57589/84315/7248/22931/51399/10890/23062/207/11337/51256/122553/79958/57706/8766/22930/55667/26130/27147/25782/9367/51560/11021/5873/79735/81631/5878/11031/23163/338382/57465/89781/160518 111 Epstein.Barr_virus R-HSA-194138 Signaling by VEGF 98/5894 107/10654 1.3679993121424331e-16 1.300523670394867e-15 4.709186821315345e-16 5295/4893/857/5335/71/5579/5291/5578/8829/1432/2534/9475/3690/5603/2475/6093/8440/9564/3845/3265/3071/8877/5062/5829/5879/26999/5290/5567/10006/57761/5921/1500/9261/6714/2321/10810/10000/3728/7410/5580/2324/7409/23191/3685/3791/1535/5600/6300/801/10787/253260/805/5170/4688/5590/653361/6461/5747/5568/3315/10451/1793/10152/7867/64223/5566/1003/10163/55845/5063/998/208/79109/2185/387/60/5058/63916/25759/558/1495/1499/4690/207/7422/10458/9047/10768/8936/3320/4846/1398/4689/9844/5228/5296/808/1536 98 Epstein.Barr_virus R-HSA-68867 Assembly of the pre-replicative complex 67/5894 68/10654 1.5631638612619807e-16 1.4760882904668503e-15 5.344905043099955e-16 5689/5682/143471/5705/5709/1869/4174/5695/84515/4998/5711/5683/990/5699/5702/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/9861/5698/5692/5713/4175/5710/5719/6233/4999/4172/5000/4173/5706/5714/51053/5688/5687/5708/81620/1870/5704/23595/7311/5694/4176/5684/5720/5690/5717/9491/10197/7316/10213/4171/1871/5715/5701/5685/5686/5716/5693/5721 67 Epstein.Barr_virus R-HSA-5687128 MAPK6/MAPK4 signaling 84/5894 89/10654 1.6029518901469946e-16 1.503568872957881e-15 5.444412033902774e-16 2308/5689/2118/3725/5682/27327/143471/5705/5709/5695/4609/5711/5683/5699/5702/192669/8997/4343/5062/5696/5691/7314/5879/5718/5700/122706/5707/5567/23198/3337/983/9861/5698/5692/5713/5710/8555/896/5719/6233/7514/26523/10602/5568/3315/5706/5597/5714/5566/5688/5687/5708/5063/998/5704/7311/5694/5058/27161/5684/5720/2309/10642/5690/57690/5717/9491/10197/192670/5596/8550/7316/10213/5715/5701/5685/5686/8556/23112/5716/5896/8202/5693/5721 84 Epstein.Barr_virus R-HSA-8854518 AURKA Activation by TPX2 71/5894 73/10654 2.533531193946859e-16 2.3451831512389678e-15 8.491891259489473e-16 7531/11190/203068/54801/79441/5116/5048/8655/6790/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/22974/3161/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 71 Epstein.Barr_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 71/5894 73/10654 2.533531193946859e-16 2.3451831512389678e-15 8.491891259489473e-16 8454/5689/7291/5682/143471/5705/5709/9978/5695/5711/5683/2101/1749/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/865/11059/2099/9861/2932/6502/5698/5692/5713/5710/5719/6233/133522/5706/579/5714/6772/5688/5687/2908/5708/4488/5704/7311/860/1750/5694/57154/5684/5720/10273/5690/5717/9491/6500/59269/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721/10891 71 Epstein.Barr_virus R-HSA-1169091 Activation of NF-kappaB in B cells 66/5894 67/10654 2.7985928227600226e-16 2.540400065563453e-15 9.198770296881838e-16 8454/5689/4790/5579/5682/143471/5705/5709/5695/4792/5711/5683/5699/5702/4794/3551/5696/5691/7314/5718/8945/5966/5700/122706/5707/23198/10892/8517/5970/9861/5698/5692/5713/5710/5719/6233/5706/8915/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/84433/5690/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5716/5693/5721 66 Epstein.Barr_virus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 66/5894 67/10654 2.7985928227600226e-16 2.540400065563453e-15 9.198770296881838e-16 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 66 Epstein.Barr_virus R-HSA-6802952 Signaling by BRAF and RAF fusions 66/5894 67/10654 2.7985928227600226e-16 2.540400065563453e-15 9.198770296881838e-16 4893/71/817/5908/55109/54845/8546/22866/5605/5037/3717/10827/2244/3690/408/5894/8826/1185/4140/3845/3265/818/8805/55750/8844/7094/5594/7414/10533/23164/57085/6714/9061/2335/1445/2266/2243/369/801/57670/805/283455/3674/409/673/816/56829/7450/60/9444/7529/5595/4000/27044/815/22906/8087/5604/10018/10142/54518/80853/10256/5906/808/9715 66 Epstein.Barr_virus R-HSA-4086400 PCP/CE pathway 86/5894 92/10654 3.798383542862491e-16 3.425849772312516e-15 1.240497729247939e-15 5689/5579/5682/5578/1212/5582/143471/5705/5709/5695/5881/5711/5683/5699/5702/57216/1855/163/5696/5691/4920/7314/5879/5718/2535/161/5700/122706/5707/1856/8322/23198/7471/8323/9861/7481/5698/5880/5692/5713/23002/5710/5719/6233/7474/1857/1213/1211/7855/1175/7976/1173/144165/409/5706/160/5714/5688/5687/4919/5708/5704/7311/387/5694/57154/5684/5720/5690/5717/9491/50855/10197/64750/7316/10213/5216/5715/5701/5685/5686/23513/5716/5693/5721/6259 86 Epstein.Barr_virus R-HSA-390466 Chaperonin-mediated protein folding 88/5894 95/10654 8.115227339495714e-16 7.27269099787928e-15 2.633436159782719e-15 2788/6000/2780/9134/1459/2770/51807/10528/1460/10381/2775/10576/1457/7846/7411/2782/81027/10574/6468/10564/54461/10693/8877/2773/5201/2787/79861/5204/10575/10681/898/10517/8786/2792/10471/26985/26330/2785/10376/2783/26190/2784/10238/7157/2771/83752/2791/5202/26224/84617/2629/2781/8237/10382/7277/6774/26272/26270/347733/55135/5082/2786/10383/60/84790/22948/7280/9628/10694/8841/54331/22803/59345/8787/5203/51764/94235/2779/7203/908/55970/346562/2793/6950/3801/55294/6499/2790 88 Epstein.Barr_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 58/5894 58/10654 1.0798343837234158e-15 9.378561591968185e-15 3.3959703815603193e-15 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/57534/388585/28514/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/102/5664/8850/3066/6233/5663/142678/10046/1024/10014/26508/9148/83464/23493/7311/55851/51107/4851/8841/23462/6500/7316/9611/54492/2033/55294/3065/54567/3516 58 Epstein.Barr_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 58/5894 58/10654 1.0798343837234158e-15 9.378561591968185e-15 3.3959703815603193e-15 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/57534/388585/28514/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/102/5664/8850/3066/6233/5663/142678/10046/1024/10014/26508/9148/83464/23493/7311/55851/51107/4851/8841/23462/6500/7316/9611/54492/2033/55294/3065/54567/3516 58 Epstein.Barr_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 58/5894 58/10654 1.0798343837234158e-15 9.378561591968185e-15 3.3959703815603193e-15 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/57534/388585/28514/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/102/5664/8850/3066/6233/5663/142678/10046/1024/10014/26508/9148/83464/23493/7311/55851/51107/4851/8841/23462/6500/7316/9611/54492/2033/55294/3065/54567/3516 58 Epstein.Barr_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 58/5894 58/10654 1.0798343837234158e-15 9.378561591968185e-15 3.3959703815603193e-15 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/57534/388585/28514/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/102/5664/8850/3066/6233/5663/142678/10046/1024/10014/26508/9148/83464/23493/7311/55851/51107/4851/8841/23462/6500/7316/9611/54492/2033/55294/3065/54567/3516 58 Epstein.Barr_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 58/5894 58/10654 1.0798343837234158e-15 9.378561591968185e-15 3.3959703815603193e-15 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/57534/388585/28514/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/102/5664/8850/3066/6233/5663/142678/10046/1024/10014/26508/9148/83464/23493/7311/55851/51107/4851/8841/23462/6500/7316/9611/54492/2033/55294/3065/54567/3516 58 Epstein.Barr_virus R-HSA-380259 Loss of Nlp from mitotic centrosomes 68/5894 70/10654 1.3983166119673712e-15 1.1996533372183485e-14 4.3439360731207164e-15 7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 68 Epstein.Barr_virus R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 68/5894 70/10654 1.3983166119673712e-15 1.1996533372183485e-14 4.3439360731207164e-15 7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 68 Epstein.Barr_virus R-HSA-450294 MAP kinase activation 63/5894 64/10654 1.6031474218821281e-15 1.3600411205235134e-14 4.924699078542479e-15 8454/3725/9252/4790/1848/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/23118/8517/5528/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/1846/79155/7867/64127/5602/3656/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/7316/7335/4205/466/23291/2002/5609/1385/5599 63 Epstein.Barr_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 76/5894 80/10654 1.6045971997647705e-15 1.3600411205235134e-14 4.924699078542479e-15 3839/23165/5335/348995/317649/57122/11274/23511/4734/23279/8672/23225/1973/3836/4599/9972/8021/7334/4938/55746/7314/402569/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/1977/51191/6233/5610/4940/6396/129401/4928/3838/5903/55706/7175/2316/4600/8638/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/7318/1974/5595/3837/81929/9631/79023/23636/7316/53371/9688/6041/4939/6059/5300/9775/5495/8480 76 Epstein.Barr_virus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 93/5894 102/10654 1.753046811355236e-15 1.4769681817825253e-14 5.3480911232016025e-15 8454/8792/7124/5689/5682/356/9039/143471/5705/10673/5709/5695/3604/7292/7133/5711/5683/5699/5702/60401/8740/944/7187/51330/958/5696/5691/939/7314/5718/8945/23495/8744/5700/122706/5707/23198/8764/9020/8741/9861/5698/5692/5713/5710/8718/9040/5719/6233/8742/4791/959/4055/8600/330/5706/5714/5688/5687/608/5708/5704/7311/5971/115650/5694/1147/4050/5684/5720/7186/5690/5717/9491/6500/10197/7316/10213/970/5715/7132/5701/329/23291/5685/5686/4049/5716/943/7293/8784/5693/5721 93 Epstein.Barr_virus R-HSA-3371556 Cellular response to heat stress 83/5894 89/10654 1.866724738739013e-15 1.5633819686939233e-14 5.660994821739863e-15 23165/6782/573/7531/1915/817/9530/348995/472/57122/3313/23511/3305/23279/1387/259217/23225/3309/9531/2475/3306/27000/9972/23411/8021/6117/3312/55746/51182/818/3303/6118/5594/3308/84335/10049/10013/3337/10762/9261/79902/9883/2932/6396/129401/3297/57521/4928/5903/55706/7175/1410/4927/64223/6119/26353/57805/3310/7266/816/8086/3326/3304/10728/5595/815/81929/9631/545/79023/23636/10808/53371/9532/9688/7415/3320/2033/6767/22824/9529/2288/8480 83 Epstein.Barr_virus R-HSA-2408557 Selenocysteine synthesis 86/5894 93/10654 2.30612123595103e-15 1.9199482715876326e-14 6.952118830272803e-15 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6171/6147/6222/6134/6155/6231/6142/23521/6207/6233/51091/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 86 Epstein.Barr_virus R-HSA-72202 Transport of Mature Transcript to Cytoplasm 79/5894 84/10654 2.378935185014957e-15 1.968918709009438e-14 7.12944043063306e-15 23165/8683/6431/84271/199746/348995/57122/23511/81608/65109/23279/23225/9877/9972/8021/55746/7919/53981/6432/8563/6430/80145/10762/22794/9785/11338/29107/4116/79902/9883/51213/10250/26097/51362/1977/57187/6396/129401/79228/2733/84324/4928/5903/55706/7175/7884/6428/10212/55110/84321/6429/4927/10898/10569/9295/10482/51692/8086/9939/6426/22916/10921/81929/9631/29894/79023/23636/4686/8189/53371/7307/9688/9984/10189/9775/84248/6427/8480/55339 79 Epstein.Barr_virus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 62/5894 63/10654 2.8667139476585268e-15 2.3587523534242964e-14 8.54102524263913e-15 5689/11065/5682/7321/8697/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/5707/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 62 Epstein.Barr_virus R-HSA-432722 Golgi Associated Vesicle Biogenesis 56/5894 56/10654 3.558854376011126e-15 2.911225643632357e-14 1.0541527037878732e-14 27131/162/1176/5286/1174/1785/8546/7037/3482/408/6456/7164/3312/1362/26258/25977/10618/6643/10053/55330/8301/2495/388552/152503/6844/54885/1213/2580/1211/23431/8907/84062/9685/9026/8775/9829/8905/51429/64746/8673/23557/2512/164/130340/6272/2804/2647/7163/286451/9698/5878/81567/10717/6845/375/4952 56 Epstein.Barr_virus R-HSA-69615 G1/S DNA Damage Checkpoints 66/5894 68/10654 4.356774855219549e-15 3.543342324447345e-14 1.2830416975517261e-14 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/993/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/1111/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 66 Epstein.Barr_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 74/5894 78/10654 4.787644836858395e-15 3.871388669804461e-14 1.4018270423711209e-14 3443/3442/4790/80143/7321/9140/79132/9474/4792/177/3093/1387/64135/83737/7187/1540/3551/7314/3445/6283/8737/29110/4214/28512/9636/841/8517/3444/8887/7323/5970/23586/7128/3451/3448/3661/3439/51191/6233/10010/55593/84282/8772/3452/4791/3446/3665/351/54476/7706/843/3440/9246/7189/7311/7318/5094/9641/3456/28511/1147/3441/7186/57506/3449/7316/4793/3146/7322/2033/6288/54941/6285/5300 74 Epstein.Barr_virus R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 100/5894 112/10654 4.834304316752332e-15 3.886780670668874e-14 1.4074004747718065e-14 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/55176/6224/6146/6154/6202/6169/6175/6218/6728/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6171/10952/6147/6222/6727/6184/6134/6747/6731/6155/6729/6231/6142/23521/6185/6207/6726/6233/6188/200916/6122/6230/6194/6166/1650/6136/6125/6232/6160/6748/29927/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/6730/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/23480/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 100 Epstein.Barr_virus R-HSA-2871837 FCERI mediated NF-kB activation 77/5894 82/10654 6.959809480918588e-15 5.563893147529803e-14 2.014681691844854e-14 8454/5689/4790/5682/7321/143471/5705/5709/5695/4792/5711/5683/5699/5702/7334/3551/5696/5691/7314/257397/5718/8945/5700/122706/5707/23198/23118/10892/8517/5970/9861/5588/5698/5692/5713/5710/10454/5719/6233/5170/2205/5706/2206/8915/5714/5688/5687/4067/5708/7189/5704/7311/5694/997/1147/5684/5720/6885/84433/5690/5717/9491/6500/10197/7316/10213/7335/7322/5715/5701/23291/5685/5686/5716/5693/5721/2207 77 Epstein.Barr_virus R-HSA-5685942 HDR through Homologous Recombination (HRR) 65/5894 67/10654 7.684612270910986e-15 6.074297452343684e-14 2.19949872212946e-14 83990/5892/9156/1763/7486/5982/472/80198/4683/84126/672/6117/10714/348654/83695/7314/6118/5888/116028/197342/7517/84464/5985/5984/6233/5884/5810/5424/80010/7516/54107/580/11073/5425/641/5111/6119/3364/10524/5427/144715/5889/5429/1111/79728/51426/146956/7311/5983/56655/51750/5883/10111/57804/675/545/7316/79008/5426/10635/23514/5932/7156/5890/5981 65 Epstein.Barr_virus R-HSA-73856 RNA Polymerase II Transcription Termination 65/5894 67/10654 7.684612270910986e-15 6.074297452343684e-14 2.19949872212946e-14 8683/6431/84271/51585/199746/81608/1477/65109/9877/7919/53981/6432/8563/6430/134353/11051/80145/8106/22794/9785/11338/4116/1478/51213/10250/26097/51362/23283/6636/10914/57187/79228/84324/6635/7884/6428/10212/84967/6637/55110/84321/6429/10898/10569/9295/51692/9939/6426/22916/1479/10921/79869/29894/4686/8189/10978/7307/9984/10189/6634/9775/84248/6427/55339/6628 65 Epstein.Barr_virus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 73/5894 77/10654 8.260827265639243e-15 6.4932871300304e-14 2.351214581928488e-14 5689/5682/51807/63943/347688/143471/10381/5705/5709/5695/5711/7846/5683/5699/5702/81027/5696/5691/7314/5718/79861/5700/122706/5707/23198/983/9861/5698/5692/5713/10376/5710/7157/5719/6233/84617/51512/10382/7277/5706/9133/891/5714/5688/5687/347733/5708/22919/5704/3326/7311/10383/5347/84790/5694/7280/5684/5720/5690/5717/9491/10197/7316/10213/1026/5715/5701/5685/3320/5686/5716/5693/5721 73 Epstein.Barr_virus R-HSA-1169408 ISG15 antiviral mechanism 69/5894 72/10654 8.69612946595737e-15 6.797474532556677e-14 2.461360620773899e-14 3839/23165/5335/348995/317649/57122/11274/23511/4734/23279/8672/23225/1973/3836/4599/9972/8021/7334/55746/7314/402569/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/1977/51191/6233/5610/6396/129401/4928/3838/5903/55706/7175/4600/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/7318/1974/5595/3837/81929/9631/79023/23636/7316/53371/9688/5300/9775/5495/8480 69 Epstein.Barr_virus R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 60/5894 61/10654 9.1577055011275e-15 7.118724663031156e-14 2.577685061090846e-14 71/51517/4651/147179/10094/8976/2885/3071/5879/26999/25/1072/10093/10006/4771/5594/4644/4641/7456/10810/7410/7409/23191/10109/10787/2214/5747/2209/10451/1793/6850/10152/10092/4650/10163/55845/998/695/3326/10097/60/5058/63916/5595/3984/4690/4627/10458/919/10552/4620/8936/917/3320/1398/10096/7454/9844/10095/2212 60 Epstein.Barr_virus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 54/5894 54/10654 1.172545360531049e-14 9.064677594874649e-14 3.2823132128226005e-14 2074/7507/5431/5435/9978/5433/10980/57654/2965/5439/10987/2967/91603/7314/404672/3150/5438/10920/2068/6233/7874/8451/10450/5434/100534599/5436/8450/4331/2966/1161/1642/2071/2873/7311/8533/5432/51138/9318/6917/5440/902/27339/5430/5441/7316/64708/5437/2033/2968/56949/9716/57461/1022/50813 54 Epstein.Barr_virus R-HSA-69563 p53-Dependent G1 DNA Damage Response 64/5894 66/10654 1.3547411371792114e-14 1.0359352065277991e-13 3.7511139038600585e-14 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Epstein.Barr_virus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 64/5894 66/10654 1.3547411371792114e-14 1.0359352065277991e-13 3.7511139038600585e-14 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Epstein.Barr_virus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 235/5894 309/10654 1.4050303688208435e-14 1.0685825561788794e-13 3.869329721247728e-14 8454/5689/127544/11065/9666/55070/5682/8916/7321/65264/9021/8697/26235/9817/9039/6478/143471/5705/8452/5709/9978/5695/23304/54620/4734/7337/84676/7704/3093/5711/23327/51465/10616/5683/25898/5699/7328/7428/5702/22954/83737/51529/140461/10075/29945/79176/8924/56658/51434/6468/10425/25793/23295/51666/90293/54461/29882/7334/55182/4591/7332/5696/5691/9820/55658/7314/996/9354/5718/197131/8945/64410/51320/5700/122706/5707/10477/148581/23198/10533/51130/6477/7323/10517/4008/84861/11059/27252/51444/26118/51433/9861/55905/6502/5698/5692/5713/26190/79654/5710/9040/7324/5719/64682/51191/6233/26091/6047/868/127247/5930/29116/26268/115290/51725/140459/23608/55585/64320/51132/899/23352/26224/10293/142678/246184/142686/151636/11146/255488/9616/91694/10193/81559/144699/5706/200845/79876/26263/8881/57630/7317/80196/55958/84078/5714/26272/8651/64219/5688/55336/5687/26270/63893/5708/55008/10422/90933/63891/9246/10393/5704/9870/9520/4012/25847/51343/7311/7318/9320/26232/57520/5694/997/7325/140691/57154/140460/5684/6737/8065/5720/84708/7319/54850/79791/26046/991/84231/10273/7320/5690/223082/5717/9491/6500/26259/10197/53339/7336/64750/51619/23376/54778/7316/10213/114907/7335/222235/25831/7322/5715/9867/5701/23291/5685/5686/55521/55294/8453/80176/8139/126433/26267/5716/23194/55284/80204/27338/23014/90678/5693/5721/51676/642 235 Epstein.Barr_virus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 59/5894 60/10654 1.635954542231414e-14 1.211467389957684e-13 4.386714672797808e-14 8454/5689/9134/5682/5705/5709/5753/5695/5711/5683/5699/5702/8900/5696/5691/7314/5718/5700/5707/898/890/9861/6502/5698/5692/5713/595/5710/5719/6233/1163/1019/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/5690/5717/1027/9491/6500/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721 59 Epstein.Barr_virus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 59/5894 60/10654 1.635954542231414e-14 1.211467389957684e-13 4.386714672797808e-14 8454/5689/5682/9039/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/5970/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 59 Epstein.Barr_virus R-HSA-5610780 Degradation of GLI1 by the proteasome 59/5894 60/10654 1.635954542231414e-14 1.211467389957684e-13 4.386714672797808e-14 8454/5689/5682/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/83737/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/8650/9861/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/2735/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Epstein.Barr_virus R-HSA-5610783 Degradation of GLI2 by the proteasome 59/5894 60/10654 1.635954542231414e-14 1.211467389957684e-13 4.386714672797808e-14 8454/5689/5682/1452/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/9861/2932/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/2736/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Epstein.Barr_virus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 59/5894 60/10654 1.635954542231414e-14 1.211467389957684e-13 4.386714672797808e-14 8454/5689/5682/1452/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/2737/9861/2932/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Epstein.Barr_virus R-HSA-1234174 Cellular response to hypoxia 71/5894 75/10654 2.453786200224006e-14 1.8075796773377887e-13 6.545232961743834e-14 5689/5682/64344/7321/3091/143471/5705/5709/9978/5695/5711/1387/5683/5699/126374/7428/5702/2056/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/405/768/112399/84962/5706/5714/10370/5688/5687/5708/5704/7311/2034/55662/5694/5684/5720/7422/5690/5717/9491/10197/7316/10213/8994/7322/5715/5701/112398/5685/5686/2033/8453/5716/54583/5693/5721 71 Epstein.Barr_virus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 58/5894 59/10654 2.9215043581379106e-14 2.1298220890673783e-13 7.712070408174249e-14 8454/5689/5682/9039/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 58 Epstein.Barr_virus R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 58/5894 59/10654 2.9215043581379106e-14 2.1298220890673783e-13 7.712070408174249e-14 5689/5682/143471/5705/5709/5695/84515/4998/5711/5683/990/5699/5702/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/4999/5000/5706/5714/51053/5688/5687/5708/81620/5704/23595/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 58 Epstein.Barr_virus R-HSA-2682334 EPH-Ephrin signaling 84/5894 92/10654 3.43250927030842e-14 2.489453888311313e-13 9.014294556859876e-14 71/2042/1947/1212/23385/2051/2045/10094/2050/285220/79784/2047/2534/9475/1948/4628/8976/6093/163/8997/1759/8440/3265/5062/5879/1072/161/10093/5921/6453/4313/2902/2041/102/6714/5664/2043/7525/1942/7410/1213/1211/1175/25791/10109/5663/1173/2904/5747/7074/1949/10627/10451/4318/160/2049/10092/4067/2044/5063/6386/998/2048/83464/10097/387/60/55851/51107/5058/4629/3984/28964/4627/3985/6383/10398/10552/4637/1946/10096/103910/10095/1969 84 Epstein.Barr_virus R-HSA-8948751 Regulation of PTEN stability and activity 66/5894 69/10654 4.589155576498909e-14 3.3112522544276745e-13 1.19900205075599e-13 5689/5682/1459/1460/143471/5705/5709/5695/1457/4734/11060/5711/5683/5699/2444/5702/8975/80351/5696/5691/7314/5718/5700/122706/5707/23198/9861/81847/5698/10000/5692/5713/5710/5719/6233/331/23608/5706/8658/5714/5688/5687/5708/208/5704/7311/5694/5684/5720/10273/207/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5728/5987/5716/5693/5721 66 Epstein.Barr_virus R-HSA-72187 mRNA 3'-end processing 57/5894 58/10654 5.215413225221073e-14 3.743921636676556e-13 1.3556713217008587e-13 8683/6431/84271/51585/199746/81608/1477/65109/9877/7919/53981/6432/8563/6430/11051/80145/8106/22794/9785/11338/4116/1478/51213/10250/26097/51362/23283/10914/57187/79228/84324/6428/10212/55110/84321/6429/10898/10569/9295/51692/9939/6426/22916/1479/10921/79869/29894/4686/8189/10978/7307/9984/10189/9775/84248/6427/55339 57 Epstein.Barr_virus R-HSA-111885 Opioid Signalling 83/5894 91/10654 5.705525243999885e-14 4.074961430613116e-13 1.4755405920897377e-13 2788/2780/5331/2770/817/5578/5582/2775/5530/107/4988/2782/5499/5518/814/2773/5515/2787/818/84152/5567/5594/10681/5142/112/5573/5528/111/5443/2792/5519/2785/2783/2784/5613/2771/5332/5580/5153/196883/115/801/2791/805/3838/2781/5568/113/10645/5566/84254/23236/816/2786/5577/1020/5141/109/5516/5533/815/5321/54331/5575/59345/5532/51764/94235/114/5330/108/2779/5173/55970/10768/346562/2793/5576/5534/1385/5144/808/2790 83 Epstein.Barr_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 69/5894 73/10654 7.265682880562159e-14 5.163038289369171e-13 1.8695324371037134e-13 892/7321/4738/9372/8239/9612/4609/4089/22938/23327/4088/5499/1030/9110/7040/904/7314/5054/7027/6497/51592/50848/7323/6667/4092/11171/7050/7046/2280/9958/9040/6233/7514/1025/7029/57530/5500/4221/5590/3726/5501/1024/23645/8812/1874/142/905/4087/7048/7311/387/57154/51377/10273/5045/50855/23370/64750/54778/7316/1875/9611/5933/867/3065/6498/56288/25937/23439 69 Epstein.Barr_virus R-HSA-1226099 Signaling by FGFR in disease 61/5894 63/10654 7.398885097996185e-14 5.231272026573182e-13 1.894239824083657e-13 5295/4893/11052/2250/5335/9530/613/5431/6776/5435/5433/11064/5439/2264/2885/9846/2252/2253/3845/3265/7750/8805/26127/5290/8823/8074/2260/5438/2249/2248/399687/2247/2246/2251/6777/1523/2963/5434/5436/9208/6774/2263/6772/2962/6654/11160/2549/5432/22916/5440/5430/8817/5441/2254/4686/26281/10818/2261/5437/2255/27006 61 Epstein.Barr_virus R-HSA-9009391 Extra-nuclear estrogen signaling 72/5894 77/10654 1.0038439614549814e-13 7.062042268835794e-13 2.5571604070747944e-13 5295/2788/374/4893/857/2770/2782/3845/3265/8877/2773/2787/1839/5290/6801/4316/5594/2069/10681/4313/2792/6714/2099/10000/2785/595/2783/2784/2771/7514/2353/801/2791/805/5170/5590/6464/5747/1903/3315/4318/8503/2786/208/1956/858/3480/5595/596/685/54331/2309/59345/207/6722/1027/51764/94235/2100/1950/55970/4314/346562/2793/3320/4846/2002/1385/5296/808/3276/2790 72 Epstein.Barr_virus R-HSA-166520 Signaling by NTRKs 90/5894 101/10654 1.5348280768289828e-13 1.0690609426229598e-12 3.8710619551080123e-13 5295/627/9252/4893/5335/5291/1848/1785/5605/5898/1432/2534/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5879/5515/5607/161/5290/3667/1849/5594/5528/1795/9261/6714/5519/5598/4208/4909/4914/6195/1213/1211/5600/1175/6300/5781/1846/25920/4908/1173/6464/2904/135/7074/160/673/6774/7867/5802/2889/6654/387/2549/1020/4916/7529/5595/25759/5516/1845/4915/5604/5045/4205/57498/10818/6014/466/4803/2002/1398/6016/1385/5906/8851/5296/581 90 Epstein.Barr_virus R-HSA-391251 Protein folding 90/5894 101/10654 1.5348280768289828e-13 1.0690609426229598e-12 3.8710619551080123e-13 2788/6000/2780/9134/1459/2770/51807/10528/1460/10381/2775/10576/1457/7846/7411/2782/81027/10574/6468/10564/54461/10693/8877/2773/5201/2787/79861/5204/10575/10681/898/10517/8786/2792/10471/26985/26330/2785/10376/2783/26190/2784/10238/7157/2771/83752/2791/6904/5202/26224/84617/2629/2781/8237/10382/7277/6774/26272/26270/347733/55135/5082/2786/10383/60/84790/22948/7280/9628/10694/8841/54331/22803/59345/8787/5203/51764/94235/2779/7203/908/55970/346562/1155/2793/6950/3801/55294/6499/2790 90 Epstein.Barr_virus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 55/5894 56/10654 1.6602643828927199e-013 1.1507349688325403e-12 4.1668030143638906e-13 5689/5682/26986/143471/5705/5709/5695/5711/5683/5699/5702/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/9861/5698/5692/5713/1981/5710/5719/6233/3315/5706/5714/5688/5687/5708/5704/7311/5694/3304/5684/5720/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 55 Epstein.Barr_virus R-HSA-9012852 Signaling by NOTCH3 49/5894 49/10654 2.3072469066434316e-13 1.5913217635526022e-12 5.762164617210635e-13 4904/182/23385/11060/22938/1387/9794/57534/9787/388585/28514/7314/23286/2648/55534/3280/84441/4854/3714/102/5664/10320/8850/5087/2173/6233/5663/23129/142678/171558/10460/10046/6772/26508/9148/83464/23493/7311/1956/55851/51107/4851/23462/7316/1950/54492/2033/54567/3516 49 Epstein.Barr_virus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 63/5894 66/10654 2.406565567629963e-13 1.6517257334904185e-12 5.980886956266506e-13 5689/5682/64344/7321/3091/143471/5705/5709/9978/5695/5711/5683/5699/126374/7428/5702/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/112399/84962/5706/5714/5688/5687/5708/5704/7311/2034/5694/5684/5720/5690/5717/9491/10197/7316/10213/8994/7322/5715/5701/112398/5685/5686/8453/5716/54583/5693/5721 63 Epstein.Barr_virus R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 70/5894 75/10654 2.900823587452583e-13 1.9717192210366105e-12 7.139581064465039e-13 23165/8683/6431/84271/199746/348995/57122/23511/65109/23279/23225/9877/9972/8021/55746/7919/6432/8563/6430/80145/10762/22794/9785/11338/29107/4116/79902/9883/51213/10250/26097/51362/57187/6396/129401/79228/2733/84324/4928/5903/55706/7175/6428/10212/55110/84321/6429/4927/10569/9295/10482/8086/9939/6426/22916/10921/81929/9631/79023/23636/4686/53371/7307/9688/9984/10189/9775/84248/6427/8480 70 Epstein.Barr_virus R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 70/5894 75/10654 2.900823587452583e-13 1.9717192210366105e-12 7.139581064465039e-13 5295/374/2250/5291/3082/941/2064/145957/2534/9965/2264/9542/2885/8660/2252/2253/5879/1839/5290/3667/6801/8823/2065/3815/2069/8074/2260/2249/6714/2099/2248/2247/5880/7409/2246/2251/3932/118788/5781/940/930/2263/4233/8503/5159/29851/3084/10718/5293/1956/2549/685/8817/2100/2254/152831/1950/50852/26281/10818/2261/2255/391/2066/27006/942/5155/4254/5296/5156 70 Epstein.Barr_virus R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 54/5894 55/10654 2.9605664178540524e-13 1.983579499962215e-12 7.182527048828879e-13 8454/5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/26271/5706/5714/5688/5687/5708/5704/51343/7311/5694/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 54 Epstein.Barr_virus R-HSA-4641257 Degradation of AXIN 54/5894 55/10654 2.9605664178540524e-13 1.983579499962215e-12 7.182527048828879e-13 5689/5682/143471/5705/5709/5695/5711/5683/5699/8312/5702/80351/5696/5691/7314/5718/5700/122706/5707/23198/9861/81847/5698/5692/5713/5710/8313/5719/6233/5706/8658/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/5716/5693/5721 54 Epstein.Barr_virus R-HSA-8941858 Regulation of RUNX3 expression and activity 54/5894 55/10654 2.9605664178540524e-13 1.983579499962215e-12 7.182527048828879e-13 5689/5682/5705/5709/5695/5711/5683/5699/5702/7040/5696/5691/7314/5718/5700/5707/865/6714/9861/5698/5692/5713/5710/5719/6233/1029/864/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/2033/5716/5693/5721/4193 54 Epstein.Barr_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 48/5894 48/10654 4.185881062583003e-13 2.7912486516844954e-12 1.0107091216214385e-12 5295/5777/1437/5291/6776/3558/3717/2534/3563/2885/9846/1399/7314/3635/5290/1439/7534/3718/3567/6233/7525/7409/6777/5781/3562/6464/1438/6850/5566/8503/2889/4067/29760/3636/6654/7006/3716/7311/5293/3561/3568/7316/3560/3055/867/1398/5296/3559 48 Epstein.Barr_virus R-HSA-195258 RHO GTPase Effectors 243/5894 327/10654 4.557133435772468e-13 3.024474879307482e-12 1.0951601702650815e-12 55839/11130/64837/71/6249/51517/5579/9735/7531/5526/51807/10811/10971/5578/9212/347688/3798/388/7533/2810/147841/147179/348995/10381/57122/6280/1780/23122/3688/5048/57405/8655/10094/23279/1432/2017/2491/7846/79784/9475/1060/81027/4628/11004/8976/1855/2885/23433/6093/9184/8826/10499/5518/23332/25909/3071/10726/81930/5062/55746/5879/5515/85415/26999/25/79682/1072/10403/79861/4638/25936/4659/10093/1856/10006/4771/389/5594/3619/64105/7534/332/5528/6714/79902/3796/5519/7456/81565/999/89953/10810/5880/91687/11243/10376/23002/11113/83540/5580/1857/128239/9055/23191/7514/147700/54820/29984/1729/5217/6396/1535/5600/801/64946/9793/30849/10109/5586/140735/5500/10787/4221/805/3831/220134/5170/84617/4928/4688/5590/114793/5903/653361/55055/5747/80776/1783/401541/2316/7532/10382/10627/79172/7277/79980/6232/5501/10152/6279/54821/10092/9183/10163/1062/699/347733/752/22919/55845/5063/3895/5529/51143/998/695/10788/286205/10097/3817/57120/367/10383/5347/387/60/84790/84643/5058/7280/4629/7529/5595/1778/5516/5905/81929/3984/27035/54908/55143/1495/1499/5525/4690/1058/991/79019/4627/348235/80152/10458/1063/3985/6722/8379/1027/1080/23421/55920/79023/6242/1781/10398/4085/5289/5585/5216/10552/81624/55166/8936/4637/51466/995/79003/391/23028/1742/5527/4689/10096/7454/701/23380/9928/3799/103910/57551/5300/808/10095/1536 243 Epstein.Barr_virus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 53/5894 54/10654 5.277176800578059e-13 3.469620447856696e-12 1.2563470592620662e-12 8454/5689/5682/143471/5705/5709/9978/5695/6790/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/23194/5693/5721 53 Epstein.Barr_virus R-HSA-9604323 Negative regulation of NOTCH4 signaling 53/5894 54/10654 5.277176800578059e-13 3.469620447856696e-12 1.2563470592620662e-12 8454/5689/5682/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/5707/7534/9861/5698/5692/5713/5710/5719/6233/5706/10460/5714/5688/5687/5708/4855/5704/7311/5694/5684/5720/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721 53 Epstein.Barr_virus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 78/5894 86/10654 7.119211996629644e-13 4.65894478105019e-12 1.6870005416738056e-12 5295/5335/71/51517/5291/4651/2268/147179/10094/2534/8976/2885/3071/5879/26999/25/1072/5290/10093/10006/5336/4771/5594/4644/4641/6714/7456/10810/7525/7410/5580/7409/23191/10109/10787/2214/5747/2209/10451/1793/6850/10152/5337/10092/4650/10163/4067/55845/998/695/3326/10097/60/5058/63916/5595/3984/23646/4690/4627/10458/919/3055/10552/10768/4620/8936/917/3320/1398/10096/7454/9844/5296/5581/5338/10095/2212 78 Epstein.Barr_virus R-HSA-76002 Platelet activation, signaling and aggregation 200/5894 262/10654 7.205932016792747e-13 4.693864049827498e-12 1.6996447836879575e-12 5295/2788/2149/5777/8526/5579/2153/5770/5291/7042/64805/2770/5175/3959/5578/5582/5908/3082/388/5583/29106/11069/2769/5028/1432/3920/374354/2244/3309/2534/3690/408/2162/2768/2782/87/2776/5894/10487/2885/51206/7040/9564/5874/350/7043/2773/967/5879/5054/2787/5099/1072/5290/5340/7225/5336/7094/5594/10681/7414/83706/7534/6810/7123/2792/6714/12/3671/7273/22927/1191/9749/3273/146850/27154/226/5588/5880/2335/5294/2785/2783/2784/1445/8525/5478/2771/94121/22915/7410/5580/2266/7409/3932/7076/2243/801/5781/2151/2791/2147/805/2814/928/5170/5590/351/6464/135228/5747/3937/2316/3674/409/6915/7277/10451/334/1277/10447/150/335/308/6850/8503/6403/197/4067/81/9948/998/3481/2786/6654/5473/8407/7450/387/29789/10916/5595/7066/151/5321/54331/5005/59345/207/7422/5004/51764/94235/5196/3827/54518/1950/55970/2812/2621/5216/2767/5768/346562/710/152/6647/4352/27040/2793/23533/1893/7078/55664/391/2/1398/948/88/2811/5906/5341/3479/5155/5296/5581/51368/808/213/5660/2815/9630/7057/1278/9002/2207/5627/6814/2790/10672 200 Epstein.Barr_virus R-HSA-167161 HIV Transcription Initiation 47/5894 47/10654 7.593576266601354e-13 4.706679210179782e-12 1.7042851439995616e-12 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Epstein.Barr_virus R-HSA-167162 RNA Polymerase II HIV Promoter Escape 47/5894 47/10654 7.593576266601354e-13 4.706679210179782e-12 1.7042851439995616e-12 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Epstein.Barr_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 47/5894 47/10654 7.593576266601354e-13 4.706679210179782e-12 1.7042851439995616e-12 8454/79718/892/3091/9978/9759/9612/4609/22938/1387/6907/9794/388585/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/7091/8850/3066/6233/7089/7090/10046/1024/10014/26508/7088/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 47 Epstein.Barr_virus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 47/5894 47/10654 7.593576266601354e-13 4.706679210179782e-12 1.7042851439995616e-12 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Epstein.Barr_virus R-HSA-6802949 Signaling by RAS mutants 47/5894 47/10654 7.593576266601354e-13 4.706679210179782e-12 1.7042851439995616e-12 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Epstein.Barr_virus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 47/5894 47/10654 7.593576266601354e-13 4.706679210179782e-12 1.7042851439995616e-12 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Epstein.Barr_virus R-HSA-73776 RNA Polymerase II Promoter Escape 47/5894 47/10654 7.593576266601354e-13 4.706679210179782e-12 1.7042851439995616e-12 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Epstein.Barr_virus R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 47/5894 47/10654 7.593576266601354e-13 4.706679210179782e-12 1.7042851439995616e-12 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Epstein.Barr_virus R-HSA-75953 RNA Polymerase II Transcription Initiation 47/5894 47/10654 7.593576266601354e-13 4.706679210179782e-12 1.7042851439995616e-12 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Epstein.Barr_virus R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 47/5894 47/10654 7.593576266601354e-13 4.706679210179782e-12 1.7042851439995616e-12 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Epstein.Barr_virus R-HSA-9649948 Signaling downstream of RAS mutants 47/5894 47/10654 7.593576266601354e-13 4.706679210179782e-12 1.7042851439995616e-12 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Epstein.Barr_virus R-HSA-199992 trans-Golgi Network Vesicle Budding 67/5894 72/10654 1.4144443873598505e-12 8.690494554652008e-12 3.1468218041009776e-12 27131/8773/8906/162/1176/27243/5286/1212/1174/1785/8546/7037/3482/408/6456/7164/3312/1362/26258/25977/10618/6643/10053/6810/55330/8301/9146/8729/4074/2495/388552/152503/6844/54885/1213/2580/1211/23431/8907/351/84062/9685/9179/9026/8775/9829/8905/51429/64746/8673/23557/2512/164/130340/6272/2799/2804/2647/7163/286451/9698/5878/81567/10717/6845/375/4952 67 Epstein.Barr_virus R-HSA-448424 Interleukin-17 signaling 67/5894 72/10654 1.4144443873598505e-12 8.690494554652008e-12 3.1468218041009776e-12 8454/3605/3725/9252/4790/1848/1432/3654/6196/5518/1386/55540/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/23118/8517/5528/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/1846/79155/7867/64127/5602/3656/7189/112744/7311/23765/6416/5595/5516/1147/1845/6885/5604/10392/6500/7316/7335/4205/466/23291/2002/5609/1385/5599 67 Epstein.Barr_virus R-HSA-180534 Vpu mediated degradation of CD4 51/5894 52/10654 1.674645298732685e-12 9.995183950933927e-12 3.6192488925687505e-12 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/920/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Epstein.Barr_virus R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 51/5894 52/10654 1.674645298732685e-12 9.995183950933927e-12 3.6192488925687505e-12 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Epstein.Barr_virus R-HSA-69610 p53-Independent DNA Damage Response 51/5894 52/10654 1.674645298732685e-12 9.995183950933927e-12 3.6192488925687505e-12 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Epstein.Barr_virus R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 51/5894 52/10654 1.674645298732685e-12 9.995183950933927e-12 3.6192488925687505e-12 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Epstein.Barr_virus R-HSA-72165 mRNA Splicing - Minor Pathway 51/5894 52/10654 1.674645298732685e-12 9.995183950933927e-12 3.6192488925687505e-12 6633/6431/4904/51639/23450/5431/5435/5433/9416/8233/23020/5439/9410/10907/10262/6432/83443/10081/5438/9343/6636/2963/6635/5434/6632/24148/154007/5436/6637/55954/57819/2962/6426/5432/22916/23451/5440/55599/5430/85437/11325/5441/79622/10594/4686/5437/11066/6634/6427/10992/6628 51 Epstein.Barr_virus R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 51/5894 52/10654 1.674645298732685e-12 9.995183950933927e-12 3.6192488925687505e-12 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/2932/5698/5692/5713/595/5710/5719/6233/1019/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Epstein.Barr_virus R-HSA-5621481 C-type lectin receptors (CLRs) 118/5894 142/10654 1.6765198382518883e-12 9.995183950933927e-12 3.6192488925687505e-12 8454/5689/4586/9252/4893/4790/5682/7321/9039/29108/143471/5705/5530/5709/5695/4792/5711/1387/5683/2534/5699/5702/5894/64170/3845/7334/3265/3551/5062/5696/5691/7314/257397/5718/8945/4773/5700/122706/5707/5567/5336/4582/23198/23118/10892/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/801/4791/805/5170/4772/5568/4775/5706/64581/6850/8915/5714/5566/5688/5687/4067/5708/5063/7189/5704/30835/7311/5971/5694/5058/997/1147/5684/5720/6885/4584/84433/5690/3553/5532/5717/9491/6500/10197/7316/10213/7335/10768/7322/5715/93978/5701/23291/5685/5686/2033/5534/5716/808/5693/5721/2207/26253 118 Epstein.Barr_virus R-HSA-187037 Signaling by NTRK1 (TRKA) 73/5894 80/10654 1.859050403941969e-12 1.1036641005680801e-11 3.996359740208362e-12 5295/9252/4893/5335/5291/1848/1785/5605/5898/1432/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5515/5607/161/5290/3667/1849/5594/5528/9261/6714/5519/5598/4208/4914/6195/1213/1211/5600/1175/6300/1846/1173/6464/135/160/673/6774/7867/2889/6654/387/7529/5595/25759/5516/1845/4915/5604/4205/57498/10818/6014/466/4803/2002/1398/6016/1385/5906/5296 73 Epstein.Barr_virus R-HSA-4086398 Ca2+ pathway 59/5894 62/10654 2.1691613684524313e-12 1.2735137331583714e-11 4.611384033581355e-12 2788/2780/5158/5331/5578/27327/2775/5530/2782/192669/6932/4343/5593/3845/2787/51176/2535/51701/8322/10681/83439/8323/2792/7481/2785/2783/2784/7474/7855/26523/801/2791/7976/805/5145/4772/6934/5148/23236/2786/27161/815/54331/6885/1499/59345/5532/57690/51764/94235/5330/192670/55970/2793/5534/23112/808/2790/5592 59 Epstein.Barr_virus R-HSA-4641258 Degradation of DVL 55/5894 57/10654 2.172304875323448e-12 1.2735137331583714e-11 4.611384033581355e-12 5689/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/1855/5696/5691/7314/5718/5700/122706/5707/1856/23198/59349/9861/5698/5692/5713/5710/5719/6233/1857/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/23072/5693/5721 55 Epstein.Barr_virus R-HSA-69541 Stabilization of p53 55/5894 57/10654 2.172304875323448e-12 1.2735137331583714e-11 4.611384033581355e-12 5689/5682/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/51230/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721/4193 55 Epstein.Barr_virus R-HSA-8951664 Neddylation 180/5894 234/10654 3.1403163512025825e-12 1.8333714133369433e-11 6.638624651592268e-12 8454/5689/5682/64344/80344/80067/55884/7321/9021/4738/26235/9817/9039/5929/3091/143471/5705/8452/5709/9978/5695/54620/7704/10980/5711/7347/5683/23113/5699/79269/10987/7428/5702/140461/79176/6468/26094/25793/1154/51666/90293/54461/5696/5691/9820/7314/51514/5718/51397/54165/8945/64410/23363/23038/5700/122706/5707/23198/55827/51130/28991/332/7323/9306/10517/50717/4008/84861/79016/27252/1643/26118/9861/6502/90864/55832/5698/5692/10920/5713/26190/10238/5710/9040/5719/10116/6233/83987/8835/127247/54939/26268/115290/54951/51725/140459/10537/8451/899/26224/9655/149951/142686/9616/5931/144699/5706/200845/26263/8450/55958/84078/5714/26272/5688/55336/5687/26270/1161/5708/1642/5704/2873/7311/2034/8533/26232/51667/5694/51122/150684/51138/56929/9318/140460/5684/8065/5720/11091/25879/54850/79791/5690/5717/9491/6500/26259/10197/53339/7316/10213/114907/64708/222235/54876/7322/5715/5701/23291/170622/5685/5686/55294/8453/80176/8139/126433/26043/123228/26267/5716/23194/80204/8883/23014/8816/5693/5721/51676/50813 180 Epstein.Barr_virus R-HSA-5610787 Hedgehog 'off' state 97/5894 113/10654 3.1991825459589416e-12 1.8600205959356327e-11 6.735121149387245e-12 8454/5689/57728/5682/11127/1452/51684/143471/10381/5705/5709/9978/5695/107/5711/7846/5683/5699/5702/81027/83737/5696/5691/7314/5718/8945/79659/5700/122706/5707/5567/23198/112/5573/2737/5727/8650/111/9861/2932/5698/5692/5713/10376/5710/5719/6233/23322/196883/115/84617/54903/10382/5568/7277/5706/113/5714/5566/2736/5688/5687/347733/5708/55811/5577/5704/7311/10383/84790/5694/7280/109/5684/5720/2735/5575/5690/5717/9491/6500/114/7289/10197/108/7316/10213/2778/5715/5701/5576/5685/5686/5716/8481/5693/5721 97 Epstein.Barr_virus R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 49/5894 50/10654 5.30514495002805e-12 3.0717444216829076e-11 1.1122764374327815e-11 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 49 Epstein.Barr_virus R-HSA-9614085 FOXO-mediated transcription 61/5894 65/10654 5.3930379974635115e-12 3.109837894439e-11 1.1260700564160221e-11 2308/857/2290/65018/57060/356/10971/7295/2810/84676/4089/1647/1387/4088/10628/4801/3630/56729/23411/2538/181/7534/847/5934/3484/5443/8850/10000/3066/604/5105/7532/4303/23410/4287/4800/901/9314/10370/2908/6794/4852/6648/4087/208/25942/7529/27113/2309/10018/4802/207/1027/6720/1649/114907/1026/2033/3065/91584/10891 61 Epstein.Barr_virus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 64/5894 69/10654 6.831530074859514e-12 3.9232501287050354e-11 1.4206060391974239e-11 23165/6782/573/7531/9530/348995/472/57122/3313/23511/3305/23279/259217/23225/3309/9531/3306/27000/9972/23411/8021/6117/3312/55746/51182/3303/6118/5594/3308/10049/3337/10762/9261/79902/9883/2932/6396/129401/3297/4928/5903/55706/7175/4927/6119/57805/3310/7266/8086/3304/5595/81929/9631/545/79023/23636/10808/53371/9532/9688/6767/22824/9529/8480 64 Epstein.Barr_virus R-HSA-5696395 Formation of Incision Complex in GG-NER 43/5894 43/10654 8.217714871832444e-12 4.700132042548069e-11 1.701914419326873e-11 6613/7507/9978/85015/2965/2067/2967/6612/6117/7334/7314/6118/404672/9557/1643/2068/6233/5886/8451/8554/8450/4331/2966/6119/1642/142/2071/1069/7329/7311/10038/902/7336/2072/54778/7316/7341/10401/2968/5887/2073/1022/7508 43 Epstein.Barr_virus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 70/5894 77/10654 8.47712298004955e-12 4.828871268392598e-11 1.7485308000613605e-11 1912/23165/7486/6045/80012/10274/348995/6613/57122/23511/54780/1911/6672/23279/23225/165918/57332/5371/8924/672/9972/6612/8021/6117/55746/79677/51564/51588/7518/10762/79902/9656/9883/84733/9063/6396/129401/7703/6015/8554/4928/5903/55706/7175/1029/8535/5885/641/493861/4927/8243/142/1069/8086/7329/648/81929/5893/9631/79023/23636/10735/53371/6996/23137/9688/7341/9126/8480/7508 70 Epstein.Barr_virus R-HSA-4608870 Asymmetric localization of PCP proteins 60/5894 64/10654 9.199604685083267e-12 5.219291851577483e-11 1.8899018113668513e-11 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/57216/5696/5691/7314/5718/2535/5700/122706/5707/1856/8322/23198/9861/5698/5692/5713/5710/5719/6233/7474/7855/7976/144165/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/50855/10197/64750/7316/10213/5715/5701/5685/5686/23513/5716/5693/5721 60 Epstein.Barr_virus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 48/5894 49/10654 9.436032054768223e-12 5.331926546609996e-11 1.93068675312104e-11 9134/57060/2810/1869/6790/25904/1647/8900/55571/55835/57472/144455/85456/29883/1263/7027/7832/898/5934/890/10769/983/7157/7029/5325/79733/1820/4869/4850/891/5111/246175/4848/23019/1874/1017/25946/4849/1027/9337/1026/5933/28984/2033/995/10498/581/3276 48 Epstein.Barr_virus R-HSA-380108 Chemokine receptors bind chemokines 56/5894 59/10654 1.1184731978076773e-11 6.244808687759531e-11 2.2612407173722463e-11 729230/7852/1237/6349/3576/6360/2920/2921/1236/6370/58191/1524/643/2833/6347/6387/10663/3579/6375/6846/6367/2826/6376/6354/3627/6346/9034/2829/1233/6366/6373/6357/6361/10803/6351/3577/10563/10850/5473/4283/6356/56477/1234/57007/1238/6374/1230/2919/5196/6352/6348/6364/6372/1235/6363/1232 56 Epstein.Barr_virus R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 56/5894 59/10654 1.1184731978076773e-11 6.244808687759531e-11 2.2612407173722463e-11 6227/6206/1965/6234/27335/6191/8668/6224/8662/26986/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1978/1968/6230/6194/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 56 Epstein.Barr_virus R-HSA-983189 Kinesins 56/5894 59/10654 1.1184731978076773e-11 6.244808687759531e-11 2.2612407173722463e-11 64837/11127/51807/347688/3798/10381/285643/10112/64147/7846/81027/11004/10749/81930/113220/79861/3797/29127/55605/3796/124602/55614/89953/56992/10376/3835/147700/3833/9493/3831/84617/9585/10382/3832/7277/23303/26153/1062/146909/347733/90990/23046/10383/24137/84790/84643/22920/7280/55582/9371/23095/547/3834/55083/3799/221458 56 Epstein.Barr_virus R-HSA-5658442 Regulation of RAS by GAPs 63/5894 68/10654 1.1521770721717241e-11 6.407561820338403e-11 2.3201735091787574e-11 5689/4893/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/3845/3265/4763/5696/5691/7314/5718/5700/122706/5707/23198/5921/9861/5698/5692/5713/5710/5719/6233/200734/22821/9462/5706/84078/5714/5688/5687/5708/5704/7311/5694/5684/5720/153090/5690/5717/9491/10197/7316/10213/5715/8437/5701/5685/5686/5716/399473/5693/5721/161742 63 Epstein.Barr_virus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 66/5894 72/10654 1.3163440152269464e-11 7.291716651276825e-11 2.640325335142321e-11 8773/55763/5563/71/7531/11127/51807/10971/347688/7533/2810/53632/10381/60412/5898/7846/81027/51552/23433/5879/79861/51422/4644/7534/6810/5872/4641/10376/11336/6844/9882/79058/801/4218/805/84617/7532/10382/7277/5571/347733/208/5867/4012/10383/60/84790/5564/5565/22920/7280/7529/55770/23265/6517/10890/9371/10640/4627/207/8766/149371/9847/808/54536/6814 66 Epstein.Barr_virus R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 42/5894 42/10654 1.4901980557054997e-11 8.222386919127993e-11 2.9773203672299766e-11 2788/6000/2780/1459/2770/1460/2775/10576/1457/2782/10574/10693/2773/2787/10575/10681/8786/2792/2785/2783/2784/2771/2791/2781/5082/2786/22948/9628/10694/54331/59345/8787/51764/94235/2779/7203/908/55970/346562/2793/6950/2790 42 Epstein.Barr_virus R-HSA-8856828 Clathrin-mediated endocytosis 119/5894 146/10654 1.8255482991054136e-11 1.0033384597036394e-10 3.633081318943339e-11 5869/374/71/5286/4738/1212/23208/1785/29763/950/8871/10094/54874/55738/10980/22848/7037/2017/3482/408/9322/10987/6456/185/8976/30011/2885/163/11037/1759/23149/3312/9185/7314/23396/1839/161/25977/5868/10618/10093/8027/1856/8322/2060/2069/1601/6453/8301/1129/9146/6455/4074/10920/26119/29979/6233/7474/6844/1213/2580/1211/29924/1175/10109/6869/1173/6857/23048/9026/409/112574/382/160/920/22905/8867/10092/9829/2873/10097/7311/1956/60/8533/51429/8673/50618/51138/9318/685/1080/29978/58513/7316/1950/273/64708/10552/26130/3267/3949/867/9341/915/917/115548/5878/1861/10096/3575/6845/551/154/10254/6457/50813/4952/11252 119 Epstein.Barr_virus R-HSA-72649 Translation initiation complex formation 55/5894 58/10654 1.9287675571252667e-11 1.0518511445252908e-10 3.808745400443203e-11 6227/6206/1965/6234/27335/6191/8668/6224/8662/26986/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1968/6230/6194/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 55 Epstein.Barr_virus R-HSA-72702 Ribosomal scanning and start codon recognition 55/5894 58/10654 1.9287675571252667e-11 1.0518511445252908e-10 3.808745400443203e-11 6227/6206/1965/6234/27335/6191/8668/6224/8662/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1968/6230/6194/1983/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 55 Epstein.Barr_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 51/5894 53/10654 2.0401206037129844e-11 1.108281733368405e-10 4.013080155241148e-11 7531/55075/10971/7533/2810/1869/8655/836/90427/840/7159/637/578/23368/7027/5594/841/7534/4836/22900/598/10000/708/3002/7157/7029/331/57099/317/140735/1029/572/7532/6774/5366/56616/8626/208/7161/7529/5595/5533/27113/596/10018/842/207/54205/5534/581/5599 51 Epstein.Barr_virus R-HSA-6809371 Formation of the cornified envelope 107/5894 129/10654 2.331070414107229e-11 1.261467720249566e-10 4.567765507805259e-11 3713/3872/125115/1823/3855/353131/353141/353134/5266/3852/6701/3861/390792/2312/7051/3880/25818/8687/147183/353142/826/353139/192666/3848/823/6706/196374/162605/3888/1475/342574/6704/26239/64065/3857/23581/8502/353135/7062/3728/140807/51350/353133/112802/54474/6700/149018/121391/353137/3860/3892/199834/144501/1828/6699/3856/2125/338785/448835/1825/3866/5318/1041/1829/8689/3884/353143/6707/353140/374454/3885/25984/6705/1832/3853/3875/286887/3849/6768/3887/3859/11187/84648/3881/3889/353145/319101/5045/3890/126638/353288/3886/9119/254910/353144/3854/5493/8688/3891/3882/6703/353132/3850/3858/6698/3868/3883 107 Epstein.Barr_virus R-HSA-5688426 Deubiquitination 219/5894 297/10654 2.4114123054072428e-11 1.2999452542942492e-10 4.707092380790907e-11 5689/221937/5682/79594/10474/7321/84196/4738/7375/9817/10445/91833/6478/3091/143471/5705/11274/55031/8239/5709/5695/4792/11047/4609/4194/4089/5711/7347/4088/114803/5683/324/408/55777/64135/5699/8312/5702/8900/8975/57599/377630/672/6881/51616/7187/7040/7345/3054/1540/80351/5696/5691/7314/5718/3607/6314/90865/2648/5700/122706/5707/8027/8737/83444/8767/171023/55611/51720/57646/23198/63967/83844/9101/8517/86/993/890/7417/80124/983/57559/4092/2099/1643/9861/23586/81847/64426/8850/7128/29844/7046/6502/5698/9146/5692/5713/5710/10454/8473/219333/7157/10869/9929/9958/8313/5719/54891/6233/9804/55593/84282/93973/10318/23770/8607/7874/5886/10600/114785/23326/93624/8237/4303/409/330/84101/5706/4287/27005/7706/580/7416/5423/79155/25862/9738/8658/84132/5714/79589/55288/27430/64127/5688/9097/5687/8078/5708/125476/4087/63891/7189/5704/7048/7311/367/114548/387/60/29761/5694/7528/9960/23358/23032/5684/8295/5720/10617/7186/56957/6885/991/51377/10392/5690/2625/57506/5717/9491/4086/1080/57695/10197/64750/29086/7316/10213/8314/55252/8678/9100/7415/5715/283899/3416/5701/4798/329/79913/9099/5685/54617/5686/2033/221656/5728/123228/5716/79184/78990/5887/5693/154/10254/5721/4193 219 Epstein.Barr_virus R-HSA-5696400 Dual Incision in GG-NER 41/5894 41/10654 2.702113781855881e-11 1.451096981324895e-10 5.254411693122725e-11 5982/7507/9978/2965/2067/2967/6117/10714/7314/6118/404672/9557/1643/5985/2068/5984/6233/5424/8451/54107/8450/5425/5111/2966/6119/5427/1642/142/2071/51426/7311/5983/10038/56655/57804/2072/7316/5426/2968/2073/5981 41 Epstein.Barr_virus R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/5894 52/10654 3.564777961572226e-11 1.9070884379970045e-10 6.905553465683239e-11 5689/5682/143471/472/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Epstein.Barr_virus R-HSA-400253 Circadian Clock 64/5894 70/10654 3.654443720154997e-11 1.9476523917644242e-10 7.052435249421923e-11 8454/79718/5936/28999/3091/5469/1628/1387/150094/6907/2155/5499/10499/23054/1386/9575/23411/9572/85441/96764/7314/5054/8945/10135/1454/5465/64784/4208/6604/80205/6233/8864/1453/5500/5187/26224/1374/1407/4783/406/4209/5501/8553/2908/1390/7311/23373/6095/8841/8204/4862/6500/200186/1408/6720/7316/9611/2033/6256/10498/1385/8648/551/10891 64 Epstein.Barr_virus R-HSA-5674135 MAP2K and MAPK activation 40/5894 40/10654 4.8992544722614254e-11 2.6012268084799343e-10 9.419023493841229e-11 4893/71/84292/5908/22866/5605/5037/2244/54756/3690/408/5894/8826/4140/3845/3265/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/28956/283455/3674/409/673/7450/60/7529/5595/5604/54518/10256/8649/5906 40 Epstein.Barr_virus R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 53/5894 56/10654 5.7190982553959357e-11 3.0251019719331134e-10 1.0953872400520904e-10 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/9861/5698/5692/5713/5710/5719/6233/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 53 Epstein.Barr_virus R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 49/5894 51/10654 6.223924060806243e-11 3.279798184851829e-10 1.1876125548709724e-10 5689/5682/143471/5705/5709/5695/5711/4946/5683/5699/5702/5696/5691/5718/1728/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/5706/4947/5714/5688/5687/5708/4953/5704/5694/5684/5720/5690/51686/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 49 Epstein.Barr_virus R-HSA-5654738 Signaling by FGFR2 66/5894 73/10654 6.293005066582368e-11 3.3038276599557433e-10 1.1963136104579205e-10 5295/4893/2250/5335/54845/5431/5435/5433/8569/5439/7072/2885/7073/5518/2252/2253/3845/3265/7314/5515/5290/8823/5594/8074/5438/3185/2249/6714/2248/4670/2247/6233/2246/2251/5781/5725/2963/5434/6464/5436/673/2263/2962/6654/7311/2549/5432/22916/5595/5516/10253/5440/5430/3178/8817/5441/2254/4686/7316/26281/10818/867/5437/2255/27006/3187 66 Epstein.Barr_virus R-HSA-674695 RNA Polymerase II Pre-transcription Events 74/5894 84/10654 8.523682474223664e-11 4.458297859194311e-10 1.614346436127667e-10 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/11198/904/51497/4300/80349/2959/404672/5438/83860/2068/1025/23168/55677/6883/7936/6829/2957/123169/25920/85403/2963/5434/5436/9646/6878/79577/4331/8148/2966/2962/4298/54457/8812/905/2071/27125/6880/6908/6882/2961/5432/22916/55840/6877/6917/5440/902/6830/5430/6749/5441/4686/6872/6879/54623/2958/5437/2968/138474/1022/8178 74 Epstein.Barr_virus R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 52/5894 55/10654 9.833166120682128e-11 5.124172122888798e-10 1.8554590262807598e-10 51807/347688/10381/1780/3305/8655/84516/832/7846/81027/3306/3312/51164/3303/79861/3337/10376/3301/10540/140735/84617/5241/11258/1783/10382/93661/10294/55860/830/7277/10671/1639/2908/347733/51143/3326/367/10383/84790/3304/7280/10728/829/1778/4306/1781/2289/10121/3320/10963/55466/2288 52 Epstein.Barr_virus R-HSA-5387390 Hh mutants abrogate ligand secretion 55/5894 59/10654 1.3070314997742277e-10 6.785953211004939e-10 2.4571887585578804e-10 5689/5682/143471/5705/5709/5695/3549/5711/5683/5699/6400/5702/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/50846/9861/5698/5692/5713/5710/5719/6233/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 55 Epstein.Barr_virus R-HSA-420499 Class C/3 (Metabotropic glutamate/pheromone receptors) 38/5894 38/10654 1.6102115542270202e-10 8.298782625631566e-10 3.004983197400724e-10 50833/5726/2550/50832/259294/2912/259295/9568/2911/2914/259296/259289/50835/338398/2916/259293/54429/222545/80835/50840/2913/2918/50838/83756/259286/259287/50836/846/259290/80834/259292/50834/259285/2917/50831/50839/50837/2915 38 Epstein.Barr_virus R-HSA-5696394 DNA Damage Recognition in GG-NER 38/5894 38/10654 1.6102115542270202e-10 8.298782625631566e-10 3.004983197400724e-10 10445/9978/10980/10987/7314/83444/86/1643/29844/10920/54891/6233/93973/8607/5886/8451/8450/1642/142/125476/1069/2873/7311/60/8533/10038/51138/7528/9318/7316/64708/283899/4798/79913/54617/5887/50813/7508 38 Epstein.Barr_virus R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 43/5894 44/10654 1.6673264088885908e-10 8.499740062703794e-10 3.077749740282524e-10 834/79370/55367/472/1387/51499/8738/7159/637/27166/23368/332/64065/8797/7157/1121/604/63970/839/317/5875/55240/5366/84883/147923/843/94241/8626/7161/10397/8795/665/27113/9540/8793/835/58484/3486/355/8794/124446/5876/581 43 Epstein.Barr_virus R-HSA-69231 Cyclin D associated events in G1 43/5894 44/10654 1.6673264088885908e-10 8.499740062703794e-10 3.077749740282524e-10 8454/5925/1869/5753/1031/3717/5520/1032/1030/5518/7314/5515/25/7027/5934/6714/5519/6502/595/896/6233/7029/1163/1019/1029/4331/4067/1874/1870/7311/5516/894/902/1027/6500/7316/1875/1026/5933/1871/1021/1022/1028 43 Epstein.Barr_virus R-HSA-69236 G1 Phase 43/5894 44/10654 1.6673264088885908e-10 8.499740062703794e-10 3.077749740282524e-10 8454/5925/1869/5753/1031/3717/5520/1032/1030/5518/7314/5515/25/7027/5934/6714/5519/6502/595/896/6233/7029/1163/1019/1029/4331/4067/1874/1870/7311/5516/894/902/1027/6500/7316/1875/1026/5933/1871/1021/1022/1028 43 Epstein.Barr_virus R-HSA-180585 Vif-mediated degradation of APOBEC3G 51/5894 54/10654 1.6888882442673195e-10 8.578576749762161e-10 3.1062964477498864e-10 5689/5682/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/60489/5706/5714/5688/5687/5708/5704/7311/5694/5684/8065/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Epstein.Barr_virus R-HSA-983231 Factors involved in megakaryocyte development and platelet production 132/5894 168/10654 1.9726547223446024e-10 9.983903576758473e-10 3.6151642772237315e-10 3443/57572/23764/64780/3442/64837/11311/11127/51807/347688/3798/10381/832/285643/3043/10112/64147/3717/7846/81027/11004/10749/2626/4097/1794/4778/7465/81930/10603/5879/3445/25/113220/79861/5868/3797/23348/23186/5567/29127/55605/3444/5573/91768/50808/1795/3796/23414/124602/3451/55614/3448/89953/56992/10376/3066/7157/3439/55669/3835/147700/3833/161882/221037/3452/9493/81704/3660/3446/9732/3831/84617/85440/9585/10382/5568/830/3832/7277/1793/23303/2623/3659/5566/26153/1062/5889/146909/347733/3440/90990/4602/998/7975/5577/23046/10383/24137/60/25942/84790/84643/3456/1020/22920/10362/7280/829/55582/1017/23468/3441/2624/9371/8165/5575/23095/2625/3449/81928/3705/5576/547/3065/23028/3834/55083/3799/51317/5890/10938/221458 132 Epstein.Barr_virus R-HSA-388841 Costimulation by the CD28 family 63/5894 70/10654 2.7879304032328925e-10 1.4059563001249748e-9 5.090957612392831e-10 5295/5777/5526/941/3115/3113/3117/2534/2885/2475/5518/3127/5062/5879/5515/1326/5290/8764/57761/3126/5528/9020/6714/5519/29126/10000/1445/916/7525/7409/3932/5781/1493/940/253260/3120/5170/3123/80380/3122/920/64223/8503/4067/29851/5063/5529/998/208/79109/3125/5058/5516/9402/5525/3119/207/919/915/917/942/5527/5296 63 Epstein.Barr_virus R-HSA-191859 snRNP Assembly 50/5894 53/10654 2.897573392589282e-10 1.4508490261114306e-9 5.253513849084893e-10 23165/6633/6606/8487/25929/348995/57122/23511/23279/23225/79084/9972/8021/55746/96764/10762/79902/9883/6636/10419/6396/129401/50628/4928/6635/5903/6632/55706/7175/6637/54960/4927/51808/8086/79833/22916/81929/11218/9631/79023/23636/10073/4686/53371/9688/1207/6634/8480/6628/79760 50 Epstein.Barr_virus R-HSA-194441 Metabolism of non-coding RNA 50/5894 53/10654 2.897573392589282e-10 1.4508490261114306e-9 5.253513849084893e-10 23165/6633/6606/8487/25929/348995/57122/23511/23279/23225/79084/9972/8021/55746/96764/10762/79902/9883/6636/10419/6396/129401/50628/4928/6635/5903/6632/55706/7175/6637/54960/4927/51808/8086/79833/22916/81929/11218/9631/79023/23636/10073/4686/53371/9688/1207/6634/8480/6628/79760 50 Epstein.Barr_virus R-HSA-176187 Activation of ATR in response to replication stress 37/5894 37/10654 2.9188349105733795e-10 1.4563123117648031e-9 5.273296366993339e-10 5982/4174/84515/4998/10926/990/84126/55388/6117/5001/6118/23594/63967/993/5985/4175/5984/5884/5810/4999/4172/5000/8318/4173/6119/3364/144715/1111/23595/5983/4176/1017/5883/8317/545/4171/995 37 Epstein.Barr_virus R-HSA-5655253 Signaling by FGFR2 in disease 42/5894 43/10654 2.956411393364047e-10 1.4646728276278922e-9 5.303569734574494e-10 5295/4893/2250/5335/5431/5435/5433/5439/2885/2252/2253/3845/3265/5290/8823/8074/5438/2249/2248/2247/2246/2251/2963/5434/5436/2263/2962/6654/2549/5432/22916/5440/5430/8817/5441/2254/4686/26281/10818/5437/2255/27006 42 Epstein.Barr_virus R-HSA-75893 TNF signaling 42/5894 43/10654 2.956411393364047e-10 1.4646728276278922e-9 5.303569734574494e-10 7124/25999/7375/9530/8439/10616/6868/1540/3551/7314/257397/90268/81858/8737/55072/23118/841/8517/8887/7128/10454/6233/6610/8772/331/8717/84888/56928/330/27005/8567/7311/1147/7186/56957/6885/7316/7132/329/9099/55512/7185 42 Epstein.Barr_virus R-HSA-73893 DNA Damage Bypass 46/5894 48/10654 3.2958376422441936e-10 1.6271030044342386e-9 5.891728232118891e-10 56852/5982/9978/25898/57599/6117/10714/55666/7314/51514/6118/9636/11201/51455/5985/5984/6233/5424/8451/124739/54107/7706/8450/5425/5111/6119/83932/5427/1642/5429/9246/51426/7311/7318/5983/56655/57804/7320/7316/5426/9100/10459/7415/7398/5981/5980 46 Epstein.Barr_virus R-HSA-447115 Interleukin-12 family signaling 53/5894 57/10654 3.7468615387498237e-10 1.8432986660912592e-9 6.674571162145434e-10 3593/5908/1265/3313/6175/3936/5898/3717/3181/4001/3594/4282/5062/3572/10148/1072/3592/6627/9049/27250/9987/3185/149233/3458/5478/302/552900/51561/7297/6775/9446/3595/821/4478/6774/6772/998/6648/3716/2939/6888/246778/3586/829/5055/6647/6950/9466/4507/6845/375/5721/5034 53 Epstein.Barr_virus R-HSA-1852241 Organelle biogenesis and maintenance 215/5894 296/10654 3.791213078868353e-10 1.8586190947622901e-9 6.730046323756768e-10 55763/5563/57728/79738/79867/55735/79718/7531/11190/203068/11127/54801/51807/1258/85302/347688/79441/53632/10381/5116/3313/5048/10576/5469/22832/10989/60412/8655/6010/89891/9702/132320/1432/1387/7846/7840/6907/2101/11064/84902/81027/84808/2847/11232/10499/23054/5518/1386/55835/9572/85441/3054/23332/7019/93323/814/96764/79659/79861/3797/10575/1454/112752/9321/23408/51422/10013/54806/5465/9727/91147/7978/54927/983/64784/79959/5310/4208/6604/80205/8729/10376/10540/11336/117177/57545/26005/54930/54820/23322/6742/378/5600/1453/6300/801/9793/4218/133522/140735/64216/57576/805/6102/80173/84617/4899/5442/11258/22981/8636/54903/80776/3842/7532/55125/10382/23082/6753/23410/121441/7277/55112/26146/9814/4209/23354/2553/146057/9738/1639/55722/4957/50807/5566/5571/2551/7283/347733/22919/27077/22994/4867/6648/1069/211/5577/10383/5347/403/84790/22948/80184/22897/5564/51106/23373/5565/22920/5108/261734/2746/57787/7280/10806/9657/1778/55770/23265/115106/10694/22995/55559/8841/9371/10142/10640/51134/95681/200186/79969/79989/7203/1781/80321/8766/9611/23409/79598/54205/149371/10121/347240/84131/6950/55212/3320/79600/10733/6256/4751/10498/80254/1385/26123/808/54536/9662/55142/8195/8648/8481/51259/55755/10891 215 Epstein.Barr_virus R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic 154/5894 202/10654 3.869677920839602e-10 1.890498900910181e-9 6.845482871660698e-10 6811/11014/64837/60592/11311/11127/51807/53407/347688/3798/5861/10381/1780/5048/8655/84516/832/285643/55738/10112/636/64147/7846/3482/51226/81027/11004/10749/6293/81930/10652/54732/7110/51164/60561/113220/79861/3797/10618/9321/29127/55275/55605/23299/51209/377/23647/9827/1315/22836/3796/5870/124602/11316/55614/89953/56992/8729/4074/23423/10376/1314/10540/3835/147700/3833/378/9493/26286/26958/140735/10959/1523/27128/3831/84364/22820/84617/11258/1783/27333/55850/9585/10382/93661/55860/830/3832/7277/10671/9554/23303/1639/8775/26153/81876/9183/9712/1062/4124/11015/146909/347733/662/90990/51143/9648/23046/10383/24137/84790/54734/84643/10945/5049/57589/51594/22920/7280/829/22931/1778/55582/5321/9371/51014/23095/5050/84316/9950/1781/22930/738/25782/10121/9367/10226/9341/9342/6836/57511/547/51560/10972/381/4905/3834/9276/55083/3799/375/221458/22818/372 154 Epstein.Barr_virus R-HSA-3928662 EPHB-mediated forward signaling 41/5894 42/10654 5.239065855402163e-10 2.541850227086498e-9 9.204021321287285e-10 71/1947/2051/10094/2050/2047/2534/9475/1948/8976/6093/8997/3265/5879/1072/10093/5921/6453/2902/6714/7525/10109/2904/5747/7074/1949/2049/10092/4067/998/2048/10097/387/60/5058/3984/3985/6383/10552/10096/10095 41 Epstein.Barr_virus R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 41/5894 42/10654 5.239065855402163e-10 2.541850227086498e-9 9.204021321287285e-10 83990/5892/9156/1763/7486/5982/472/4683/84126/672/6117/83695/6118/5888/116028/7517/5985/5984/5884/5810/80010/7516/580/11073/641/6119/3364/10524/144715/5889/1111/79728/5983/5883/10111/675/545/10635/5932/7156/5890 41 Epstein.Barr_virus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 36/5894 36/10654 5.290575124695803e-10 2.558020343796218e-9 9.262573197152354e-10 4893/71/5908/22866/5605/5037/2244/3690/408/5894/8826/4140/3845/3265/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/283455/3674/409/673/7450/60/7529/5595/5604/54518/10256/5906 36 Epstein.Barr_virus R-HSA-6783783 Interleukin-10 signaling 45/5894 47/10654 5.734420935821727e-10 2.7631268002401264e-9 1.0005262195161196e-9 729230/7124/1437/3593/5743/941/3383/6349/3576/2920/1435/7133/3606/6347/3588/3569/3592/3587/6367/3976/3627/7076/7850/7297/3557/6351/6774/1440/3552/3716/1234/3586/3554/2208/3553/1230/2919/2357/6352/6348/6364/7132/942/6363/5724 45 Epstein.Barr_virus R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 48/5894 51/10654 8.49986633936104e-10 4.081676429856991e-9 1.4779720884680233e-9 6227/6206/1965/6234/27335/6191/8668/6224/8662/6202/6218/3921/8665/6208/6203/8666/6222/8667/6231/8663/8894/6207/6233/51386/6188/1968/6230/6194/6232/6193/6210/6229/6205/6235/6223/8664/6187/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 48 Epstein.Barr_virus R-HSA-351202 Metabolism of polyamines 54/5894 59/10654 1.2013753342331935e-9 5.7494390995445685e-9 2.0818677471137332e-9 5689/5682/143471/5705/5709/5695/5711/4946/5683/5699/5702/5696/5691/5718/1728/5700/122706/5707/23198/6723/9861/5698/5692/5713/5710/5719/6303/5706/4947/5714/5688/5687/5708/4953/5704/262/113451/5694/5684/5720/5690/51686/5717/9491/10197/10213/5715/6611/5701/5685/5686/5716/5693/5721 54 Epstein.Barr_virus R-HSA-194315 Signaling by Rho GTPases 313/5894 455/10654 1.3603138879745025e-9 6.488005560610593e-9 2.349302129454627e-9 55839/9639/11130/394/398/64837/71/6249/51517/5579/392/9735/7531/5526/29/51807/10811/10971/5578/9212/347688/613/3798/1894/388/7533/2810/147841/147179/348995/116985/54509/10381/57122/6280/1780/23122/3688/5048/57405/8655/10094/23279/5881/1432/2017/2491/9138/7846/23365/79784/9475/1060/171177/26230/9322/397/81027/4628/57449/51291/11004/8976/1855/2885/23433/6093/9184/8997/8826/10499/5518/23332/25909/3071/10726/81930/5062/55746/9411/2665/5879/5515/9181/85415/26999/25/79682/64333/1072/10403/79861/4638/25936/4659/10093/1856/10006/4771/389/5594/29127/3619/64105/89839/7534/332/5528/6453/9828/6714/79902/3796/5519/7456/81565/57636/999/89953/396/10810/5880/85360/91687/11243/10376/23002/57584/11113/58504/83540/7410/5580/7409/1857/128239/9055/23191/7514/147700/54820/29984/1729/5217/6396/1535/5600/91614/25791/801/64946/9793/30849/10109/5586/140735/9886/2664/5500/10787/4221/805/3831/220134/5170/84617/4928/4688/9743/5590/114793/5903/653361/55055/5747/80776/1783/401541/7204/64411/2316/7532/3633/27237/10382/7074/10627/79172/7277/10451/79980/58480/6232/5501/50650/10152/6279/55288/54821/10092/9183/4650/10163/1062/699/94134/347733/752/22919/55845/5063/3895/5529/51143/998/695/10788/286205/6654/10097/3817/57120/367/57381/10383/5347/387/60/84790/84643/5058/93663/7280/4629/7529/5595/1778/5516/5905/81929/3984/27035/54908/55143/1495/1499/5525/4690/1058/991/79019/4627/10928/348235/80152/10458/1063/3985/6722/8379/1027/9459/11214/1080/23421/55920/79023/23370/6242/1781/9824/10398/4085/5289/5585/5216/4168/10552/81624/23263/55166/8936/23092/4637/51466/995/79003/391/23221/23028/89941/2/1742/90627/5527/4689/10096/7454/701/23380/9928/3799/103910/57551/5296/5300/84986/808/10095/1536/399/4952/10672 313 Epstein.Barr_virus R-HSA-5675221 Negative regulation of MAPK pathway 39/5894 40/10654 1.6421916079482004e-9 7.805958082375399e-9 2.8265317860843847e-9 4893/1844/1850/1848/5526/1852/5605/5037/5894/1847/5518/4140/3845/3265/7314/5515/8844/1849/5594/5528/5519/80824/6233/1843/369/1846/11221/673/8315/5529/7311/5536/7529/5595/5516/5604/5525/7316/5527 39 Epstein.Barr_virus R-HSA-9006936 Signaling by TGF-beta family members 85/5894 102/10654 1.7033068133008508e-9 8.069200964021202e-9 2.921851843479042e-9 892/7321/4738/9372/130399/8239/9612/4609/4089/22938/23327/4088/5499/1030/9110/7040/10589/904/7314/5054/7027/11167/6497/51592/50848/7323/91/93/6667/4092/11171/7050/7046/92/94/2280/9958/9040/6233/7514/1025/7029/8928/57530/4091/5500/4090/4221/4093/5590/9765/269/3726/5501/1024/23645/8812/1874/142/905/4087/7048/7311/387/57154/51377/10273/5045/50855/4086/23370/64750/659/54778/7316/1875/9611/5933/867/3065/6498/657/56288/25937/23439 85 Epstein.Barr_virus R-HSA-4615885 SUMOylation of DNA replication proteins 43/5894 45/10654 1.73093581941202e-9 8.172572811787624e-9 2.95928271492553e-9 23165/9212/348995/6613/57122/23511/6790/23279/23225/9972/6612/8021/55746/7150/51588/3619/7153/332/10762/79902/9883/7155/6396/129401/4928/5903/55706/7175/5111/4927/8086/7329/5905/81929/55143/9631/79023/23636/53371/9688/7341/10401/8480 43 Epstein.Barr_virus R-HSA-8848021 Signaling by PTK6 50/5894 54/10654 1.8006137746613517e-9 8.44487860316174e-9 3.057884445389804e-9 4893/1796/5770/9021/27043/3091/116985/2064/5753/145957/9542/9564/3845/3265/5829/7314/5879/120892/1839/2065/2069/898/202559/5921/6421/595/6233/1019/10657/1793/6774/2908/3084/10718/7311/2034/387/1956/63916/1017/685/207/55620/1027/7316/1950/867/2066/1398/9844 50 Epstein.Barr_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 50/5894 54/10654 1.8006137746613517e-9 8.44487860316174e-9 3.057884445389804e-9 4893/1796/5770/9021/27043/3091/116985/2064/5753/145957/9542/9564/3845/3265/5829/7314/5879/120892/1839/2065/2069/898/202559/5921/6421/595/6233/1019/10657/1793/6774/2908/3084/10718/7311/2034/387/1956/63916/1017/685/207/55620/1027/7316/1950/867/2066/1398/9844 50 Epstein.Barr_virus R-HSA-438064 Post NMDA receptor activation events 70/5894 81/10654 1.885431752938245e-9 8.813297263734588e-9 3.1912885764018553e-9 5563/4893/51807/817/347688/53632/10381/107/7846/81027/1739/6196/6197/3845/3265/814/5879/5923/818/57554/79861/5567/5594/51422/5573/2902/6714/10376/6195/5613/801/2891/4747/805/5170/84617/3838/2904/2890/10382/5568/7277/10645/5566/84254/5571/27330/347733/3084/816/5577/5562/10383/84790/5564/5565/7280/5595/815/28964/5575/114/5576/4137/2066/1742/88/1385/808/8536 70 Epstein.Barr_virus R-HSA-8878171 Transcriptional regulation by RUNX1 176/5894 239/10654 2.665205304382234e-9 1.241703265982054e-8 4.496198561592894e-9 1912/9070/5689/1437/5579/5682/1459/6045/9021/5929/27327/80012/1460/143471/8013/5705/5709/5695/28996/1457/1911/6603/10413/5711/1387/3558/5683/10138/57332/5699/8312/5702/192669/83737/5371/57492/6688/4343/4778/5696/5691/7314/55170/5718/84661/25/5275/4773/8861/196528/5700/122706/5707/23198/86/100506658/865/1515/7082/23309/51412/6714/2099/9861/8850/84733/5588/6604/8289/5698/5692/5713/6602/595/5710/3458/1998/896/5719/23067/6233/84870/161882/26523/5781/1493/23429/55193/6015/1514/55904/6595/3562/6597/6929/8535/3674/7122/1378/6938/3958/5706/6599/200845/4331/57678/2623/5714/5688/5687/5708/6886/4602/5704/7311/7161/860/58508/25942/648/5694/6601/23466/4297/4004/27161/894/5684/5720/902/2624/11091/640/8085/5690/2625/57690/5717/9491/4005/6598/10197/192670/5196/7316/10213/5079/10398/1513/122809/5715/5701/5685/5686/2033/1021/84333/6605/50943/3065/861/23112/26053/9757/5716/2811/9739/8784/3276/3977/3559/7057/1022/5693/5721/1997 176 Epstein.Barr_virus R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 38/5894 39/10654 2.904569251961728e-9 1.348755424920842e-8 4.883833656242753e-9 83990/5892/9156/1763/7486/5982/472/4683/84126/672/6117/83695/6118/5888/116028/5985/5984/5884/5810/80010/7516/580/11073/641/6119/3364/10524/144715/5889/1111/5983/5883/10111/675/545/5932/7156/5890 38 Epstein.Barr_virus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 42/5894 44/10654 3.002719606734853e-9 1.3851890120248978e-8 5.015759412112748e-9 892/7321/8239/9612/4609/4089/22938/23327/4088/1030/904/7314/5054/7027/6497/51592/7323/6667/4092/7050/6233/1025/7029/4221/3726/1024/8812/1874/142/905/4087/7311/64750/54778/7316/1875/9611/5933/3065/6498/25937/23439 42 Epstein.Barr_virus R-HSA-451927 Interleukin-2 family signaling 42/5894 44/10654 3.002719606734853e-9 1.3851890120248978e-8 5.015759412112748e-9 5295/5777/1437/5291/6776/84868/3558/3717/3563/2885/9846/3600/3635/5290/1439/50615/3718/3567/3932/6777/59067/3562/6464/6775/1438/3581/6774/6850/6772/8503/3636/6654/3716/5293/2185/3561/3578/3568/3560/5296/3559/3601 42 Epstein.Barr_virus R-HSA-169911 Regulation of Apoptosis 49/5894 53/10654 3.029977881893853e-9 1.3931957123609971e-8 5.044751616225059e-9 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 49 Epstein.Barr_virus R-HSA-163359 Glucagon signaling in metabolic regulation 33/5894 33/10654 3.1490792959704213e-9 1.4246799258618595e-8 5.1587557260100996e-9 2788/107/2782/2787/5567/112/5573/111/2785/2783/2784/196883/115/2791/5568/2642/113/5566/2641/2786/5577/109/54331/5575/59345/51764/94235/114/108/55970/2778/5576/2790 33 Epstein.Barr_virus R-HSA-1980145 Signaling by NOTCH2 33/5894 33/10654 3.1490792959704213e-9 1.4246799258618595e-8 5.1587557260100996e-9 182/23385/4853/9794/57534/388585/28514/7314/55534/3280/84441/3714/1272/102/5664/3002/6233/5663/4192/142678/10046/9148/83464/7311/55851/51107/2208/7316/54492/2033/1385/54567/3516 33 Epstein.Barr_virus R-HSA-2559585 Oncogene Induced Senescence 33/5894 33/10654 3.1490792959704213e-9 1.4246799258618595e-8 5.1587557260100996e-9 2077/27327/5925/2114/1869/4194/1031/192669/1032/1030/4343/7314/7027/5594/6667/7157/6233/7029/26523/1019/1029/1870/7311/3397/2113/5595/57690/192670/7316/1871/1021/23112/4193 33 Epstein.Barr_virus R-HSA-68962 Activation of the pre-replicative complex 33/5894 33/10654 3.1490792959704213e-9 1.4246799258618595e-8 5.1587557260100996e-9 5422/4174/84515/4998/10926/990/55388/6117/5001/5558/6118/23594/5557/4175/23649/4999/4172/5000/8318/54107/4173/51053/6119/5427/81620/29935/23595/4176/56655/1017/8317/5426/4171 33 Epstein.Barr_virus R-HSA-9022692 Regulation of MECP2 expression and activity 33/5894 33/10654 3.1490792959704213e-9 1.4246799258618595e-8 5.1587557260100996e-9 2290/79718/817/9212/27327/28996/9612/6907/192669/4204/4343/814/818/3066/26523/801/805/3930/5566/816/25942/27161/815/8841/57690/192670/9611/2874/3064/3065/23112/1385/808 33 Epstein.Barr_virus R-HSA-5678895 Defective CFTR causes cystic fibrosis 55/5894 61/10654 3.3697210125925536e-9 1.5196145720249114e-8 5.502513394381902e-9 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/5696/5691/7314/5718/5700/122706/5707/10956/79139/91445/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 55 Epstein.Barr_virus R-HSA-5617833 Cilium Assembly 151/5894 201/10654 3.5627676404985653e-9 1.6015380415915276e-8 5.799157686232741e-9 55763/57728/79738/79867/7531/11190/203068/11127/54801/51807/1258/85302/347688/79441/10381/5116/5048/10576/22832/60412/8655/6010/89891/9702/132320/7846/7840/11064/84902/81027/2847/5518/55835/23332/93323/79659/79861/3797/10575/1454/112752/9321/10013/54806/9727/91147/983/79959/5310/8729/10376/10540/11336/117177/57545/26005/54930/54820/23322/378/1453/9793/4218/140735/57576/6102/80173/84617/11258/22981/8636/54903/80776/3842/7532/55125/10382/6753/121441/7277/55112/26146/9814/23354/146057/9738/1639/55722/4957/50807/5566/7283/347733/22919/27077/22994/4867/1069/5577/10383/5347/403/84790/22948/80184/22897/22920/5108/261734/57787/7280/10806/9657/1778/55770/23265/115106/10694/22995/55559/9371/10142/10640/51134/95681/79969/79989/7203/1781/80321/8766/79598/149371/10121/347240/84131/6950/55212/3320/79600/10733/4751/80254/26123/54536/9662/55142/8195/8481/51259/55755 151 Epstein.Barr_virus R-HSA-157118 Signaling by NOTCH 173/5894 235/10654 3.7918724497514984e-009 1.6990969862421524e-8 6.1524179204818145e-9 8454/5689/3725/79718/5682/892/4904/113878/182/27327/3091/23385/5705/5709/9978/1869/5695/9759/9612/4609/11060/22938/5711/1387/4088/6907/5683/408/5699/6400/4853/5702/192669/83737/6868/9794/56983/6487/57534/4343/9787/388585/5696/5691/28514/7314/5718/23286/79885/23509/2648/9734/7027/55869/5700/5707/51564/487/55534/3280/84441/10013/7534/83933/4854/3714/7091/8650/1272/102/5664/10320/9861/5870/8850/5087/2173/5698/5692/5713/595/5710/3002/3066/7157/5719/6233/2324/7029/7089/26523/5663/10959/1999/4192/23129/4242/7090/142678/23220/171558/409/5706/10402/10460/10046/5986/1024/5714/6772/10014/489/5688/5687/5708/59/26508/9148/4855/7088/5704/83464/23493/7311/1956/55851/51107/5694/4851/27161/5684/8841/2208/5720/5584/23462/207/5690/5045/57690/5717/9491/6500/51548/3955/10197/192670/488/7316/10213/1950/9611/54492/6484/1871/5715/5701/5685/5686/2033/55294/3065/861/92737/2683/23112/5716/1385/1840/54567/3516/5693/5721 173 Epstein.Barr_virus R-HSA-418597 G alpha (z) signalling events 45/5894 48/10654 4.231317033948421e-9 1.889988275163628e-8 6.8436338995189174e-9 2788/5579/2770/5578/5582/5583/107/2782/6004/2773/2787/10681/112/111/2792/5588/2785/2783/2784/2771/5580/196883/115/2791/2781/150/113/10287/8601/2786/109/151/54331/59345/51764/94235/114/108/55970/2778/346562/152/2793/5581/2790 45 Epstein.Barr_virus R-HSA-69481 G2/M Checkpoints 129/5894 168/10654 4.692182675218223e-9 2.089209184820266e-8 7.565011375101998e-9 5689/83990/5682/9156/1763/7531/7486/10971/5982/7533/2810/11200/143471/472/5705/5709/4174/5695/84515/4998/5711/4683/10926/5683/990/165918/84126/5699/5702/8924/55388/672/6117/7334/5001/7465/5696/83695/5691/7314/5718/6118/23594/5700/122706/5707/51588/51720/23198/63967/7534/993/116028/983/9861/9656/5698/5692/5985/5713/4175/5710/7157/5984/5719/6233/7158/5884/5810/4999/4172/80010/5000/8318/51512/7532/4173/5706/9133/580/11073/891/641/5714/6119/3364/10524/5688/5687/144715/5708/1111/5704/23595/7311/5983/5694/4176/7529/1017/5684/5720/5883/10111/8317/5690/5717/9491/545/10197/7336/29086/7316/10213/4171/5715/9088/7341/5701/5685/5686/995/5716/5932/9025/79184/7156/5693/5721 129 Epstein.Barr_virus R-HSA-2980766 Nuclear Envelope Breakdown 48/5894 52/10654 5.0910289993739625e-9 2.259645994359358e-8 8.18216183196745e-9 23165/5579/91754/5578/348995/57122/23511/23279/23225/9663/4001/9972/8021/55746/10762/983/79902/9883/221496/7444/2010/64900/23175/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/5347/7112/4000/81929/9631/140609/10783/79023/23636/7443/53371/9688/8815/23592/8480 48 Epstein.Barr_virus R-HSA-168325 Viral Messenger RNA Synthesis 41/5894 43/10654 5.20334823271842e-9 2.3022361520235273e-8 8.336380485388002e-9 23165/348995/57122/5431/23511/5435/5433/23279/23225/5439/9972/8021/55746/5438/10762/79902/9883/6396/129401/4928/2963/5434/5903/55706/7175/5436/4927/2962/8086/5432/81929/5440/9631/5430/79023/5441/23636/53371/9688/5437/8480 41 Epstein.Barr_virus R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 51/5894 56/10654 5.508880807703905e-9 2.4221860301373107e-8 8.7707181280549e-9 79718/5469/1387/6907/2101/84808/11232/10499/23054/1386/9572/85441/3054/7019/814/96764/23408/5465/7978/64784/4208/6604/80205/6742/801/133522/64216/805/4899/5442/23082/23410/4209/2553/2551/6648/211/51106/23373/2746/8841/200186/9611/23409/54205/6256/10498/1385/808/8648/10891 51 Epstein.Barr_virus R-HSA-429914 Deadenylation-dependent mRNA decay 51/5894 56/10654 5.508880807703905e-9 2.4221860301373107e-8 8.7707181280549e-9 5393/80153/23404/26986/28960/219988/25904/1973/10767/55571/11340/57472/85456/29883/80349/51690/11157/1981/1977/23016/118460/9924/23644/5073/27258/4850/9652/255967/57819/246175/4848/23019/23658/1975/51010/56915/1974/167227/22894/1656/27257/4849/25804/9337/55802/51013/196513/9775/54464/6499/54512 51 Epstein.Barr_virus R-HSA-2871796 FCERI mediated MAPK activation 32/5894 32/10654 5.706161767621595e-9 2.4552200633160805e-8 8.890334123704658e-9 3725/4893/5335/2885/3845/3265/5062/5879/5601/5336/5594/4214/7410/7409/2353/6464/2205/3937/10451/2206/6850/4067/5602/6654/5058/6416/5595/9402/27040/5609/5599/2207 32 Epstein.Barr_virus R-HSA-381042 PERK regulates gene expression 32/5894 32/10654 5.706161767621595e-9 2.4552200633160805e-8 8.890334123704658e-9 5393/1965/23404/3576/3309/4801/6347/11340/468/3484/1054/8894/9451/8570/23016/118460/1968/5073/1051/4800/22926/51010/56915/167227/22894/440/9709/4802/1649/51013/467/54512 32 Epstein.Barr_virus R-HSA-392518 Signal amplification 32/5894 32/10654 5.706161767621595e-9 2.4552200633160805e-8 8.890334123704658e-9 2788/64805/2770/2769/5028/1432/2782/2776/2773/2787/10681/2792/6714/2785/2783/2784/2771/2791/6915/2786/5321/54331/59345/51764/94235/55970/2767/346562/2793/9630/2790/10672 32 Epstein.Barr_virus R-HSA-397795 G-protein beta:gamma signalling 32/5894 32/10654 5.706161767621595e-9 2.4552200633160805e-8 8.890334123704658e-9 2788/5331/2782/2787/10681/2792/146850/10000/5294/2785/2783/2784/2791/5170/23236/998/695/2786/208/387/5058/54331/59345/207/9459/51764/94235/5330/55970/2793/23533/2790 32 Epstein.Barr_virus R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 32/5894 32/10654 5.706161767621595e-9 2.4552200633160805e-8 8.890334123704658e-9 2788/2149/2769/408/2768/2782/2776/2787/5594/10681/2792/6714/2785/2783/2784/2151/2791/2147/409/2786/5595/54331/59345/51764/94235/55970/2767/2793/9630/9002/2790/10672 32 Epstein.Barr_virus R-HSA-5673000 RAF activation 32/5894 32/10654 5.706161767621595e-9 2.4552200633160805e-8 8.890334123704658e-9 4893/5526/817/5605/3717/4296/5894/5518/4140/3845/3265/5515/818/8844/5528/6714/5519/369/801/805/673/8315/5529/816/7529/5516/815/5604/5525/5527/808/5245 32 Epstein.Barr_virus R-HSA-69190 DNA strand elongation 32/5894 32/10654 5.706161767621595e-9 2.4552200633160805e-8 8.890334123704658e-9 2237/1763/5982/5422/4174/84515/84296/6117/10714/5558/6118/64785/3978/5557/5985/4175/5984/23649/5424/4172/8318/4173/5425/5111/6119/51659/5983/4176/57804/9837/4171/5981 32 Epstein.Barr_virus R-HSA-5689603 UCH proteinases 84/5894 102/10654 6.7136025969572555e-9 2.879889894487457e-8 1.0428060516454787e-8 5689/221937/5682/4738/10445/143471/5705/5709/5695/11047/5711/7347/5683/55777/5699/5702/7040/7345/3054/5696/5691/7314/5718/3607/5700/122706/5707/83444/171023/23198/86/4092/9861/29844/7046/5698/5692/5713/5710/8473/9958/5719/54891/6233/93973/8607/114785/5706/580/5714/5688/5687/5708/125476/5704/7048/7311/60/5694/7528/5684/5720/51377/5690/5717/9491/10197/7316/10213/8314/55252/5715/283899/5701/4798/79913/5685/54617/5686/221656/123228/5716/5693/5721 84 Epstein.Barr_virus R-HSA-5358351 Signaling by Hedgehog 116/5894 149/10654 6.7373794075669154e-9 2.881304810470106e-8 1.0433183917012915e-8 8454/5689/57728/5682/11127/22873/1452/51684/143471/10381/5705/8452/5709/9978/5695/107/3549/5711/7846/5683/408/5699/6400/5702/81027/83737/6868/6469/5696/5691/7314/5718/8945/79659/339745/5700/122706/5707/5567/10956/23198/112/5573/2737/5727/8650/111/50846/9861/8405/2932/5698/5692/5713/10376/5710/5719/6233/23322/196883/115/84617/54903/10382/23288/5568/409/79577/7277/5706/113/84447/5714/5566/2736/5688/5687/347733/5708/55811/5577/5704/7311/10383/84790/5694/7280/109/57154/5684/5720/2735/5575/5690/5717/9491/6500/114/7289/10197/108/64750/7316/10213/2778/7415/5715/5701/5576/5685/5686/5716/8481/5693/5721/5034 116 Epstein.Barr_virus R-HSA-2408522 Selenoamino acid metabolism 95/5894 118/10654 7.030969852325642e-9 2.99774987340066e-8 1.08548306492045e-8 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/1491/6175/6218/6173/6167/116832/6156/6143/6139/3921/3176/6208/6170/7296/6203/6171/6147/4143/191/6222/2936/27232/6134/6155/6231/6142/9061/23521/6207/6233/51091/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/7965/6124/6189/6135/6201/6161/6133 95 Epstein.Barr_virus R-HSA-73762 RNA Polymerase I Transcription Initiation 44/5894 47/10654 7.205763374345401e-9 3.0537677914771024e-8 1.1057671126135618e-8 2074/9112/5435/5928/2965/64425/1107/2967/2648/404672/8850/57459/2068/3066/9533/5434/9015/79101/9219/5931/221830/7270/4331/9013/1108/2966/54815/2071/57504/6908/53615/5440/902/9014/25885/5441/51082/7343/5437/3065/2968/84172/1022/10919 44 Epstein.Barr_virus R-HSA-9020591 Interleukin-12 signaling 44/5894 47/10654 7.205763374345401e-9 3.0537677914771024e-8 1.1057671126135618e-8 3593/5908/1265/3313/6175/3936/5898/3717/3181/4001/3594/4282/5062/1072/3592/6627/9049/27250/9987/3185/3458/5478/302/552900/7297/6775/9446/3595/4478/998/6648/3716/2939/6888/3586/829/5055/6647/6950/4507/6845/375/5721/5034 44 Epstein.Barr_virus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 40/5894 42/10654 9.006693527777124e-9 3.8055308689436675e-8 1.37797998022574e-8 23165/348995/57122/23511/81608/23279/23225/9972/8021/55746/53981/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/7884/4927/10898/10482/51692/8086/22916/81929/9631/29894/79023/23636/4686/8189/53371/9688/10189/8480/55339 40 Epstein.Barr_virus R-HSA-5685938 HDR through Single Strand Annealing (SSA) 36/5894 37/10654 9.067322283310363e-9 3.808275358990353e-8 1.3789737580902483e-8 83990/9156/1763/7486/5982/472/4683/84126/2067/672/6117/83695/6118/25/5888/116028/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/5983/5893/5883/10111/545/2072/5932/7156 36 Epstein.Barr_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 36/5894 37/10654 9.067322283310363e-9 3.808275358990353e-8 1.3789737580902483e-8 11200/472/639/4194/8900/2475/5518/51230/7314/5515/6446/117584/890/983/5519/10000/900/7157/6233/7874/253260/5170/1029/80196/64223/1616/208/79109/7311/5516/1017/207/7316/9099/5527/4193 36 Epstein.Barr_virus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 31/5894 31/10654 1.0338829346314907e-8 4.3293847887693677e-8 1.56766710639612e-8 3725/9252/1848/1432/6196/5518/1386/6197/51231/5515/5601/1849/5594/5528/9261/5519/5598/4208/6195/2353/5600/1846/5602/5595/5516/1845/4205/466/2002/1385/5599 31 Epstein.Barr_virus R-HSA-190236 Signaling by FGFR 73/5894 87/10654 1.34157295372588e-8 5.601166605021701e-8 2.0281783838929432e-8 5295/4893/2250/5335/54845/5431/5435/5433/8569/9965/5439/2264/7072/2885/7073/5518/2252/2253/3845/3265/7314/5515/5290/8823/5594/8074/2260/5438/3185/2249/6714/2248/4670/2247/6233/2246/2251/200734/5781/5725/2963/5434/6464/5436/673/2263/2962/6654/7311/2549/5432/22916/5595/5516/10253/5440/5430/3178/8817/5441/2254/4686/7316/152831/26281/10818/2261/867/5437/2255/27006/3187/161742 73 Epstein.Barr_virus R-HSA-8986944 Transcriptional Regulation by MECP2 55/5894 62/10654 1.372903409916484e-8 5.715015082107967e-8 2.0694028352525013e-8 627/2571/2290/79718/5770/817/9212/27327/6657/28996/9612/4988/6907/192669/4204/3654/4343/6750/814/28514/818/6446/54487/4208/2593/3066/26523/801/2891/805/2904/3930/4233/5566/1392/816/25942/27161/815/8841/5468/4986/57690/192670/114787/9611/2874/2289/5775/3064/5728/3065/23112/1385/808 55 Epstein.Barr_virus R-HSA-1227986 Signaling by ERBB2 46/5894 50/10654 1.4304815143532382e-8 5.91966909027943e-8 2.1435079038605795e-8 5295/4893/5335/5578/2064/5753/145957/2534/4145/9542/2885/3845/3265/7314/1839/5290/2065/2069/9101/6714/10000/6233/7525/5580/1729/6464/5782/10193/3084/208/6654/10718/7311/387/1956/2549/11140/8065/685/10273/207/7316/1950/3320/2066/5581 46 Epstein.Barr_virus R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 46/5894 50/10654 1.4304815143532382e-8 5.91966909027943e-8 2.1435079038605795e-8 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/2209/5706/5714/5688/5687/5708/5704/5694/5684/5720/5690/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721/4360 46 Epstein.Barr_virus R-HSA-74751 Insulin receptor signalling cascade 49/5894 54/10654 1.5077746132772262e-8 6.22122838968052e-8 2.2527023084617302e-8 5295/3643/4893/2250/5291/9965/2264/3630/2885/8660/9846/2252/2253/3845/3265/54106/5290/3667/8823/5594/8074/57761/2260/2249/2248/2247/2246/2251/5781/30849/5170/6464/2322/2263/208/6654/2549/5595/8817/2254/152831/5289/26281/10818/2261/2255/27006/5296/2887 49 Epstein.Barr_virus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 39/5894 41/10654 1.5571875955683682e-8 6.387647075698816e-8 2.312962394522296e-8 23165/348995/57122/23511/81608/23279/23225/9972/8021/55746/53981/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10898/10482/51692/8086/22916/81929/9631/29894/79023/23636/4686/8189/53371/9688/10189/8480/55339 39 Epstein.Barr_virus R-HSA-5654743 Signaling by FGFR4 39/5894 41/10654 1.5571875955683682e-8 6.387647075698816e-8 2.312962394522296e-8 5295/4893/5335/8569/9965/2264/2885/5518/2253/3845/3265/7314/5515/5290/8823/5594/8074/2249/6714/2247/6233/2246/2251/5781/6464/673/6654/7311/2549/5595/5516/10253/8817/2254/7316/152831/26281/10818/867 39 Epstein.Barr_virus R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 35/5894 36/10654 1.6002567554590685e-8 6.526264507046114e-8 2.3631556663377242e-8 71/51517/147179/10094/8976/2885/3071/5879/26999/25/10093/10006/5594/7456/10810/23191/10109/10787/5747/10152/10092/10163/55845/998/695/10097/60/5595/4690/10458/10552/8936/10096/7454/10095 35 Epstein.Barr_virus R-HSA-6804757 Regulation of TP53 Degradation 35/5894 36/10654 1.6002567554590685e-8 6.526264507046114e-8 2.3631556663377242e-8 11200/472/4194/8900/2475/5518/51230/7314/5515/6446/117584/890/983/5519/10000/900/7157/6233/7874/253260/5170/1029/80196/64223/1616/208/79109/7311/5516/1017/207/7316/9099/5527/4193 35 Epstein.Barr_virus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 30/5894 30/10654 1.8731194231795628e-8 7.551515840726775e-8 2.734398434079048e-8 56852/5982/9978/57599/6117/10714/7314/51514/6118/5985/5984/6233/5424/8451/54107/8450/5425/5111/6119/5427/1642/7311/5983/56655/57804/7320/7316/5426/7398/5981 30 Epstein.Barr_virus R-HSA-114452 Activation of BH3-only proteins 30/5894 30/10654 1.8731194231795628e-8 7.551515840726775e-8 2.734398434079048e-8 7531/10971/7533/2810/1869/8655/90427/7159/637/23368/7027/7534/10000/7157/7029/140735/572/7532/5366/8626/208/7161/7529/5533/27113/596/10018/207/5534/5599 30 Epstein.Barr_virus R-HSA-180786 Extension of Telomeres 30/5894 30/10654 1.8731194231795628e-8 7.551515840726775e-8 2.734398434079048e-8 2237/1763/5982/5422/6117/10714/5558/6118/3978/5557/5985/5984/23649/8607/5424/55651/54107/5425/5111/6119/5427/55135/5983/56655/7015/57804/10856/5426/1736/5981 30 Epstein.Barr_virus R-HSA-4090294 SUMOylation of intracellular receptors 30/5894 30/10654 1.8731194231795628e-8 7.551515840726775e-8 2.734398434079048e-8 7068/6613/7181/4929/9759/8856/7067/6612/5914/7421/10062/51588/2516/5465/2099/2494/9063/8554/5241/2908/9971/7329/367/6095/5468/4306/7341/10401/6256/7376 30 Epstein.Barr_virus R-HSA-5358346 Hedgehog ligand biogenesis 57/5894 65/10654 1.9572477585218598e-8 7.868135989257876e-8 2.8490463612769324e-8 5689/5682/143471/5705/5709/5695/3549/5711/5683/5699/6400/5702/6868/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/50846/9861/5698/5692/5713/5710/5719/6233/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721/5034 57 Epstein.Barr_virus R-HSA-8943724 Regulation of PTEN gene transcription 54/5894 61/10654 2.2160166821849524e-8 8.883007042262758e-8 3.2165304368796426e-8 1912/3725/6591/1822/9112/6045/80012/1911/5928/23512/57332/1107/2475/1386/23186/2146/51564/5594/84232/7101/84733/57459/3066/7157/8726/57521/6015/28956/389541/9219/8535/5931/1108/2122/64223/10014/54815/6009/55004/57504/648/23466/53615/5595/8841/5468/5978/57167/1958/8649/6615/3065/23028/10542 54 Epstein.Barr_virus R-HSA-2428924 IGF1R signaling cascade 48/5894 53/10654 2.4877119727183354e-8 9.943780527314482e-8 3.600635749987064e-8 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/8471/2246/2251/5781/30849/5170/6464/2322/2263/3481/208/6654/2549/3480/8817/2254/152831/5289/26281/10818/2261/2255/27006/3479/5296 48 Epstein.Barr_virus R-HSA-8953750 Transcriptional Regulation by E2F6 34/5894 35/10654 2.821978977759915e-8 1.1247944537416999e-7 4.072872596498581e-8 80314/6045/80012/79813/11335/1869/1911/5928/10138/23512/672/6241/5888/83746/7027/2146/1876/7029/8726/8409/7703/317/23429/6015/84108/5931/1111/648/23468/23269/8317/4149/5932/10919 34 Epstein.Barr_virus R-HSA-5632684 Hedgehog 'on' state 71/5894 85/10654 3.129898252677966e-8 1.2440019326321746e-7 4.5045220169376614e-8 5689/5682/11127/22873/1452/51684/143471/5705/8452/5709/9978/5695/3549/5711/5683/408/5699/5702/83737/6469/5696/5691/7314/5718/339745/5700/122706/5707/23198/2737/5727/8650/50846/9861/8405/5698/5692/5713/5710/5719/6233/23288/409/79577/5706/5714/2736/5688/5687/5708/5704/7311/5694/57154/5684/5720/2735/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/5716/5693/5721 71 Epstein.Barr_virus R-HSA-73887 Death Receptor Signalling 109/5894 141/10654 3.854042235882536e-8 1.5275035002497825e-7 5.531079146529718e-8 7124/25999/9639/4790/7531/29/356/7375/9530/8878/1894/23385/4792/8439/9138/836/23365/10616/26230/57449/3654/6868/8997/1540/3551/7314/5879/257397/9181/90268/81858/8737/8767/55072/23118/841/8517/8887/6453/9828/5970/5664/8797/7128/396/10454/3066/6233/7410/7409/6610/26574/8772/331/8717/25791/8743/5663/84888/56928/572/7204/27237/7074/330/10451/27005/50650/843/8837/8567/7189/6654/83464/7311/387/55851/51107/8795/1147/4804/57142/8841/7186/56957/6885/5584/10018/8793/835/9459/355/11214/23421/23370/4615/9500/7316/4168/23263/7132/329/9099/4803/3065/55512/5599/7185/10672 109 Epstein.Barr_virus R-HSA-2428928 IRS-related events triggered by IGF1R 47/5894 52/10654 4.09679118275311e-8 1.6146177014379904e-7 5.846519040107637e-8 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/8471/2246/2251/5781/30849/5170/2322/2263/3481/208/6654/2549/3480/8817/2254/152831/5289/26281/10818/2261/2255/27006/3479/5296 47 Epstein.Barr_virus R-HSA-383280 Nuclear Receptor transcription pathway 47/5894 52/10654 4.09679118275311e-8 1.6146177014379904e-7 5.846519040107637e-8 7068/5915/8013/6097/7181/4929/5469/2104/9612/8856/2101/7067/5914/9572/8431/7421/10062/7025/2516/5465/2099/7101/2494/5467/2103/6257/190/5241/7182/3172/2649/2063/9970/2908/9971/367/6095/5468/2100/4306/9611/3164/6256/7376/6258/5916/9975 47 Epstein.Barr_virus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 37/5894 39/10654 4.63743720747155e-8 1.8225905449476174e-7 6.599587204987445e-8 5982/25898/6117/10714/55666/7314/6118/9636/11201/51455/5985/5984/6233/5424/124739/54107/7706/5425/5111/6119/83932/5427/5429/9246/51426/7311/7318/5983/56655/57804/7316/5426/9100/10459/7415/5981/5980 37 Epstein.Barr_virus R-HSA-5654727 Negative regulation of FGFR2 signaling 33/5894 34/10654 4.9722601168772866e-8 1.9487381572273933e-7 7.056366798324605e-8 2250/8569/2885/5518/2252/2253/7314/5515/8823/5594/8074/2249/6714/2248/2247/6233/2246/2251/5781/673/2263/7311/5595/5516/10253/8817/2254/7316/26281/10818/867/2255/27006 33 Epstein.Barr_virus R-HSA-9612973 Autophagy 94/5894 119/10654 5.062213232215329e-8 1.9784816715908243e-7 7.164067849100055e-8 51652/5563/2670/65018/1459/1915/27243/9140/8878/1460/53632/5116/55048/9474/8655/1457/51271/3043/3920/29082/55054/55062/2475/84557/3312/11315/92421/7314/137492/64422/139341/25978/51160/9821/51422/7249/10533/10013/91782/79720/192111/440738/6714/8408/89853/123/55669/6233/9804/30849/57521/140735/28956/7405/79643/389541/22863/7416/26100/1068/64223/5571/128866/6009/3326/55004/7311/5562/93343/55626/7251/5564/5565/7248/155382/11337/10452/1080/64419/6035/7316/83734/11152/5289/8678/56993/10226/8649/3320/81631/10542/23710/54543/7431 94 Epstein.Barr_virus R-HSA-1433557 Signaling by SCF-KIT 40/5894 43/10654 5.971796412856007e-8 2.321082196930498e-7 8.40462187793634e-8 5295/5777/4893/5578/6776/3717/2534/2242/1215/2885/9846/3845/3265/10603/5879/5290/3815/9306/6714/7525/7409/3932/6777/5781/2241/4318/6774/6772/8651/8503/4067/1111/6654/7006/9402/867/4254/5296/10076/2887 40 Epstein.Barr_virus R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 40/5894 43/10654 5.971796412856007e-8 2.321082196930498e-7 8.40462187793634e-8 2788/358/107/2782/2787/22841/5567/10681/112/5573/111/2792/2785/2783/2784/196883/115/2791/5568/359/113/5566/2786/5577/109/54331/5575/59345/51764/94235/114/108/8766/55970/2778/2793/5576/4645/551/2790 40 Epstein.Barr_virus R-HSA-202040 G-protein activation 28/5894 28/10654 6.146871615446053e-8 2.3760022975089552e-7 8.603487165632995e-8 2788/2780/2770/2775/4988/2782/2773/2787/10681/5443/2792/2785/2783/2784/2771/2791/2781/2786/54331/59345/51764/94235/2779/5173/55970/346562/2793/2790 28 Epstein.Barr_virus R-HSA-350054 Notch-HLH transcription pathway 28/5894 28/10654 6.146871615446053e-8 2.3760022975089552e-7 8.603487165632995e-8 79718/9759/9612/22938/1387/6907/4853/9794/79885/2648/9734/55869/51564/55534/84441/10013/83933/4854/8850/3066/10046/10014/4855/4851/8841/9611/3065/3516 28 Epstein.Barr_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 49/5894 55/10654 6.371776899091795e-8 2.456189067677303e-7 8.893842881500875e-8 834/4790/7295/29108/1432/10628/5603/83737/3654/64170/7334/1540/3551/7314/257397/8767/23118/841/8517/5970/7128/598/10454/6233/5600/6300/5608/4791/351/330/64127/3656/7189/3326/7311/114548/1147/9447/596/6885/842/10392/10910/835/58484/7316/7335/22861/329 49 Epstein.Barr_virus R-HSA-4570464 SUMOylation of RNA binding proteins 43/5894 47/10654 6.652032082751578e-8 2.557215612139746e-7 9.259659269634063e-8 1912/23165/6045/80012/348995/6613/57122/23511/3190/1911/23279/23225/57332/9972/8021/55746/51602/10762/79902/9883/84733/6396/129401/7703/6015/4928/5903/55706/7175/8535/4927/8086/7329/648/81929/9631/79023/23636/3183/53371/9688/7341/8480 43 Epstein.Barr_virus R-HSA-167172 Transcription of the HIV genome 62/5894 73/10654 6.700365979288495e-8 2.5687779108607394e-7 9.301526269828283e-8 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/11198/904/51497/2959/404672/5438/83860/2068/1025/6883/7936/6829/2957/25920/2963/5434/5436/6878/4331/8148/2966/2962/54457/8812/905/2071/6880/6908/6882/2961/5432/22916/6877/6917/5440/902/5430/6749/5441/4686/6872/8731/6879/2958/5437/2968/138474/1022/8178 62 Epstein.Barr_virus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 36/5894 38/10654 7.987090501119813e-8 3.03725306353394e-7 1.0997871415482189e-7 23165/348995/57122/23511/23279/23225/7428/5371/9972/8021/55746/51588/10762/79902/9883/9063/6396/129401/8554/4928/5903/55706/7175/4927/8086/7329/81929/9631/79023/23636/53371/9688/7341/5987/8480/4193 36 Epstein.Barr_virus R-HSA-5655302 Signaling by FGFR1 in disease 36/5894 38/10654 7.987090501119813e-8 3.03725306353394e-7 1.0997871415482189e-7 5295/4893/11052/2250/5335/9530/613/6776/11064/2885/9846/2253/3845/3265/7750/8805/26127/5290/8074/2260/2249/399687/2247/2246/2251/6777/1523/9208/6774/6772/6654/11160/2549/2254/26281/10818 36 Epstein.Barr_virus R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 36/5894 38/10654 7.987090501119813e-8 3.03725306353394e-7 1.0997871415482189e-7 1912/1459/6045/80012/1460/28996/1457/1911/6603/10138/57332/57492/196528/86/865/51412/84733/6604/8289/6602/23429/55193/6015/6595/6597/8535/6599/648/6601/23466/6598/2033/84333/6605/861/26053 36 Epstein.Barr_virus R-HSA-1839126 FGFR2 mutant receptor activation 32/5894 33/10654 8.753280086045953e-8 3.3018405043074144e-7 1.195594062832296e-7 2250/5431/5435/5433/5439/2252/2253/8823/8074/5438/2249/2248/2247/2246/2251/2963/5434/5436/2263/2962/5432/22916/5440/5430/8817/5441/2254/4686/26281/5437/2255/27006 32 Epstein.Barr_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 32/5894 33/10654 8.753280086045953e-8 3.3018405043074144e-7 1.195594062832296e-7 4790/4792/177/3654/7334/3551/7314/257397/6283/8767/28512/23118/8517/5970/10454/6233/4791/351/64127/3656/7189/7311/28511/1147/6885/10392/7316/7335/4793/3146/6288/6285 32 Epstein.Barr_virus R-HSA-5357905 Regulation of TNFR1 signaling 32/5894 33/10654 8.753280086045953e-8 3.3018405043074144e-7 1.195594062832296e-7 7124/25999/7375/10616/1540/3551/7314/90268/81858/8737/55072/841/8517/8887/7128/6233/331/8717/84888/56928/330/27005/8567/7311/1147/7186/56957/7316/7132/329/9099/7185 32 Epstein.Barr_virus R-HSA-163685 Integration of energy metabolism 86/5894 108/10654 9.53666170029077e-8 3.587722730563934e-7 1.2991118105659252e-7 2788/5563/5313/5331/2770/5578/11069/2769/107/9495/2782/3630/2776/8826/5518/31/777/2181/6513/5515/2787/5567/1131/51422/10681/112/5573/5528/111/2792/5519/51085/2785/2783/2784/2771/9370/7086/6844/2182/196883/115/2791/5568/2642/150/113/6616/5566/775/2864/23236/6794/2641/6514/2786/5577/6888/773/5565/109/5516/54331/5575/59345/776/51764/94235/114/4082/5330/3790/108/55970/2778/2194/2767/10768/152/2793/5576/948/47/5906/9630/2790 86 Epstein.Barr_virus R-HSA-168253 Host Interactions with Influenza Factors 39/5894 42/10654 1.0091924751847017e-7 3.776419714321477e-7 1.367438852153963e-7 3839/23165/348995/57122/23511/23279/23225/3836/9972/8021/7040/55746/402569/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/293/4927/10898/3840/8086/3837/81929/9631/79023/23636/53371/9688/8480 39 Epstein.Barr_virus R-HSA-2426168 Activation of gene expression by SREBF (SREBP) 39/5894 42/10654 1.0091924751847017e-7 3.776419714321477e-7 1.367438852153963e-7 79718/5469/6713/1387/6907/4801/6309/10499/23054/85441/7108/31/96764/4598/5465/2222/3157/6667/3156/6604/80205/10654/6721/9453/4800/57678/1595/4047/4802/6720/2194/4597/1717/6256/10498/2224/3422/4520/8648 39 Epstein.Barr_virus R-HSA-112043 PLC beta mediated events 48/5894 54/10654 1.0327210848247142e-7 3.844017371291992e-7 1.3919159149405782e-7 2780/5331/2770/817/5578/5582/2775/107/814/2773/818/5567/5594/112/5573/111/5613/2771/5332/5580/5153/196883/115/801/805/3838/2781/5568/113/10645/5566/84254/23236/816/5577/109/815/5321/5575/114/5330/108/2779/10768/346562/5576/1385/808 48 Epstein.Barr_virus R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 48/5894 54/10654 1.0327210848247142e-7 3.844017371291992e-7 1.3919159149405782e-7 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/8471/2246/2251/5781/30849/5170/6464/2322/2263/3481/208/6654/2549/3480/8817/2254/152831/5289/26281/10818/2261/2255/27006/3479/5296 48 Epstein.Barr_virus R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress 27/5894 27/10654 1.1133936365663085e-7 4.1224864385494636e-7 1.492749363152613e-7 5393/23404/3576/4801/6347/11340/468/3484/1054/8570/23016/118460/5073/1051/4800/22926/51010/56915/167227/22894/440/9709/4802/1649/51013/467/54512 27 Epstein.Barr_virus R-HSA-912526 Interleukin receptor SHC signaling 27/5894 27/10654 1.1133936365663085e-7 4.1224864385494636e-7 1.492749363152613e-7 5295/5777/1437/5291/3558/3717/3563/2885/9846/3635/5290/1439/3718/3567/3562/6464/1438/8503/3636/6654/3716/5293/3561/3568/3560/5296/3559 27 Epstein.Barr_virus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 31/5894 32/10654 1.5395152428580683e-7 5.655608215930293e-7 2.0478916518985983e-7 892/4609/4089/22938/4088/1030/904/7314/5054/7027/6667/4092/7050/6233/1025/7029/4221/3726/1024/8812/1874/905/4087/7311/54778/7316/1875/5933/3065/25937/23439 31 Epstein.Barr_virus R-HSA-5656169 Termination of translesion DNA synthesis 31/5894 32/10654 1.5395152428580683e-7 5.655608215930293e-7 2.0478916518985983e-7 5982/6117/10714/7314/6118/9636/11201/51455/5985/5984/6233/5424/124739/54107/7706/5425/5111/6119/5427/5429/9246/51426/7311/7318/5983/56655/57804/7316/5426/9100/5981 31 Epstein.Barr_virus R-HSA-917729 Endosomal Sorting Complex Required For Transport (ESCRT) 31/5894 32/10654 1.5395152428580683e-7 5.655608215930293e-7 2.0478916518985983e-7 51652/27243/55048/51271/29082/27183/92421/7314/137492/25978/51160/8027/91782/79720/51534/89853/51510/9146/6233/79643/11267/128866/7311/93343/7251/51028/155382/7316/9525/10254/84313 31 Epstein.Barr_virus R-HSA-3899300 SUMOylation of transcription cofactors 41/5894 45/10654 1.8360546941319653e-7 6.727419152717905e-7 2.4359936183110507e-7 1912/6045/80012/6613/28996/9612/1911/9994/1387/57332/4152/115426/10499/6612/11315/3622/51588/1655/84733/10155/9063/7690/7703/6015/8554/8535/4869/10210/10521/1616/7329/25942/648/1487/8204/7341/10401/2033/6294/8648/10891 41 Epstein.Barr_virus R-HSA-168638 NOD1/2 Signaling Pathway 34/5894 36/10654 2.3591256756874503e-7 8.576976293778404e-7 3.105716923793624e-7 834/1432/5603/83737/3654/64170/7334/1540/3551/7314/257397/8767/23118/841/8517/7128/10454/6233/5600/6300/5608/330/64127/3656/7189/7311/1147/6885/842/10392/835/7316/7335/329 34 Epstein.Barr_virus R-HSA-176033 Interactions of Vpr with host cellular proteins 34/5894 36/10654 2.3591256756874503e-7 8.576976293778404e-7 3.105716923793624e-7 23165/348995/57122/23511/292/23279/23225/3836/9972/8021/55746/10762/79902/11168/9883/6396/129401/4928/5903/55706/7175/293/4927/8086/81929/9631/3159/79023/23636/53371/9688/8815/8480/291 34 Epstein.Barr_virus R-HSA-177243 Interactions of Rev with host cellular proteins 34/5894 36/10654 2.3591256756874503e-7 8.576976293778404e-7 3.105716923793624e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/5902/7514/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/1104/5905/3837/81929/9631/79023/23636/53371/9688/8480 34 Epstein.Barr_virus R-HSA-2122948 Activated NOTCH1 Transmits Signal to the Nucleus 30/5894 31/10654 2.7050214079621947e-7 9.783972033426241e-7 3.5427692097245356e-7 113878/182/23385/408/83737/6868/57534/28514/7314/3714/8650/1272/102/5664/6233/5663/142678/23220/409/9148/83464/7311/55851/51107/4851/7316/54492/92737/1840/54567 30 Epstein.Barr_virus R-HSA-5654733 Negative regulation of FGFR4 signaling 30/5894 31/10654 2.7050214079621947e-7 9.783972033426241e-7 3.5427692097245356e-7 8569/9965/2264/2885/5518/2253/7314/5515/8823/5594/8074/2249/6714/2247/6233/2246/2251/5781/673/7311/5595/5516/10253/8817/2254/7316/152831/26281/10818/867 30 Epstein.Barr_virus R-HSA-168276 NS1 Mediated Effects on Host Pathways 37/5894 40/10654 2.8668477897484365e-7 1.0316252788174042e-6 3.73550768673642e-7 3839/23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/402569/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/4927/10898/3840/8086/3837/81929/9631/79023/23636/53371/9688/8480 37 Epstein.Barr_virus R-HSA-5654741 Signaling by FGFR3 37/5894 40/10654 2.8668477897484365e-7 1.0316252788174042e-6 3.73550768673642e-7 5295/4893/2250/5335/8569/2885/5518/2253/3845/3265/7314/5515/5290/8823/5594/8074/2249/6714/2247/6233/2246/5781/6464/673/6654/7311/2549/5595/5516/10253/8817/2254/7316/26281/10818/2261/867 37 Epstein.Barr_virus R-HSA-112399 IRS-mediated signalling 43/5894 48/10654 2.9524289112322465e-7 1.0597110913530028e-6 3.8372062111611363e-7 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/2246/2251/5781/30849/5170/2322/2263/208/6654/2549/8817/2254/152831/5289/26281/10818/2261/2255/27006/5296 43 Epstein.Barr_virus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 25/5894 25/10654 3.652064784474567e-7 1.284613787938929e-6 4.6515772518044483e-7 11065/7321/8697/51529/29945/51434/9184/29882/7314/996/51433/119504/7324/64682/6233/246184/8881/10393/7311/25906/991/7316/4085/4751/701 25 Epstein.Barr_virus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 25/5894 25/10654 3.652064784474567e-7 1.284613787938929e-6 4.6515772518044483e-7 9252/1848/1432/6196/5518/6197/51231/5515/1849/5594/5528/9261/5519/5598/4208/6195/5600/1846/5595/5516/1845/4205/466/2002/1385 25 Epstein.Barr_virus R-HSA-392451 G beta:gamma signalling through PI3Kgamma 25/5894 25/10654 3.652064784474567e-7 1.284613787938929e-6 4.6515772518044483e-7 2788/2782/2787/10681/2792/146850/10000/5294/2785/2783/2784/2791/5170/2786/208/387/54331/59345/207/51764/94235/55970/2793/23533/2790 25 Epstein.Barr_virus R-HSA-418592 ADP signalling through P2Y purinoceptor 1 25/5894 25/10654 3.652064784474567e-7 1.284613787938929e-6 4.6515772518044483e-7 2788/2769/5028/1432/2782/2776/2787/10681/2792/6714/2785/2783/2784/2791/2786/5321/54331/59345/51764/94235/55970/2767/2793/9630/2790 25 Epstein.Barr_virus R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 25/5894 25/10654 3.652064784474567e-7 1.284613787938929e-6 4.6515772518044483e-7 5982/6117/10714/7314/6118/3978/5985/5984/6233/5424/7515/54107/5425/5111/6119/5427/51426/7311/3980/5983/56655/57804/7316/5426/5981 25 Epstein.Barr_virus R-HSA-9006335 Signaling by Erythropoietin 25/5894 25/10654 3.652064784474567e-7 1.284613787938929e-6 4.6515772518044483e-7 5295/4893/5335/5291/6776/3717/2885/2056/8660/3845/3265/1399/5290/5336/5294/2057/7409/6777/6464/2889/4067/6654/5293/2549/23533 25 Epstein.Barr_virus R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus 25/5894 25/10654 3.652064784474567e-7 1.284613787938929e-6 4.6515772518044483e-7 4904/182/23385/11060/57534/28514/7314/4854/3714/102/5664/6233/5663/142678/10460/9148/83464/7311/1956/55851/51107/7316/1950/54492/54567 25 Epstein.Barr_virus R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 25/5894 25/10654 3.652064784474567e-7 1.284613787938929e-6 4.6515772518044483e-7 22938/1387/9794/9787/388585/23286/2648/55534/3280/84441/4854/10320/8850/5087/2173/23129/171558/10046/6772/26508/23493/4851/23462/2033/3516 25 Epstein.Barr_virus R-HSA-112040 G-protein mediated events 48/5894 55/10654 3.745018649959837e-7 1.3124465965925575e-6 4.7523596509991234e-7 2780/5331/2770/817/5578/5582/2775/107/814/2773/818/5567/5594/112/5573/111/5613/2771/5332/5580/5153/196883/115/801/805/3838/2781/5568/113/10645/5566/84254/23236/816/5577/109/815/5321/5575/114/5330/108/2779/10768/346562/5576/1385/808 48 Epstein.Barr_virus R-HSA-5693532 DNA Double-Strand Break Repair 123/5894 166/10654 3.7498474188358785e-7 1.3124465965925575e-6 4.7523596509991234e-7 2237/83990/151987/5892/9156/1763/7486/5982/11200/472/6613/80198/3981/2140/64421/4683/165918/84126/8900/8924/2067/672/6117/7334/10714/348654/83695/55183/7314/6118/25/5888/322/51588/7518/51720/63967/5531/116028/2070/890/197342/7517/9656/84464/5985/7157/5984/6233/7158/6047/5884/5810/5424/8467/80010/3838/7516/7515/54107/51567/580/11073/5591/5425/641/5111/6119/3364/22976/10524/5427/144715/5889/55775/5429/142/1111/9682/10721/7329/79728/51426/146956/7311/23030/3980/5536/5983/10038/2547/56655/51750/1017/54962/5893/5883/10111/57804/7520/675/51548/545/7336/2072/29086/7316/8314/79008/5426/10635/7341/8914/23514/5932/2138/9025/79184/7156/5890/5599/5981/2139 123 Epstein.Barr_virus R-HSA-6790901 rRNA modification in the nucleus and cytosol 53/5894 62/10654 3.980243506157692e-7 1.3896284399910355e-6 5.031834548727498e-7 55226/10528/84135/27340/88745/51096/55272/51077/23160/10607/11103/6208/22984/10813/9136/6203/51504/54433/27292/56902/51602/9724/54555/10171/5822/2091/55651/55127/8602/6194/10436/9277/84128/4839/134430/92856/65083/115939/11056/9790/55505/51202/57647/6187/79050/55813/25879/57050/1736/10199/27341/6201/10885 53 Epstein.Barr_virus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 33/5894 35/10654 4.045189891231356e-7 1.4053289325833377e-6 5.08868591905387e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/7884/4927/10482/8086/22916/81929/9631/79023/23636/4686/53371/9688/10189/8480 33 Epstein.Barr_virus R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 33/5894 35/10654 4.045189891231356e-7 1.4053289325833377e-6 5.08868591905387e-7 23165/91754/348995/57122/23511/23279/23225/9972/8021/55746/10762/983/79902/9883/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/81929/9631/140609/10783/79023/23636/53371/9688/8480 33 Epstein.Barr_virus R-HSA-3928665 EPH-ephrin mediated repulsion of cells 45/5894 51/10654 4.3377712269441646e-7 1.5032620976134089e-6 5.443301202595217e-7 71/2042/1947/1212/23385/2051/2045/2050/285220/2047/2534/1948/163/1759/5879/161/4313/2041/102/6714/5664/2043/7525/1942/7410/1213/1211/1175/5663/1173/7074/1949/10451/4318/160/2049/4067/2044/2048/83464/60/55851/51107/1946/1969 45 Epstein.Barr_virus R-HSA-199977 ER to Golgi Anterograde Transport 115/5894 154/10654 4.500527764820843e-7 1.555833554079343e-6 5.633662066916561e-7 6811/23256/374/6711/11014/126003/10960/2153/51807/10484/347688/5861/10381/1780/90411/8655/84516/832/3998/55738/7846/51226/9632/3630/81027/6709/79090/10652/54732/51164/58485/79861/10342/4253/2801/377/22872/1315/8615/11316/8729/23423/10376/1314/10540/83696/27095/6399/7109/378/6396/26286/1453/26958/140735/10959/84364/22820/84617/11258/6712/2890/1783/10382/10802/93661/55860/830/7277/10671/9554/966/11196/1639/10282/6710/8775/81876/11015/347733/51143/51693/23243/5537/9871/10383/84790/10945/1075/7280/829/1778/9919/10113/51399/55291/51014/122553/1781/10121/2804/57511/22870/10972/381/4905/89866/9276/287/375/64689/288/10427/22818/372 115 Epstein.Barr_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 29/5894 30/10654 4.7479505378855876e-7 1.633341419756729e-6 5.91431748896313e-7 7124/7375/10616/1540/3551/7314/257397/81858/8737/55072/23118/8517/7128/10454/6233/331/8717/330/27005/7311/1147/7186/56957/6885/7316/7132/329/9099/7185 29 Epstein.Barr_virus R-HSA-6804758 Regulation of TP53 Activity through Acetylation 29/5894 30/10654 4.7479505378855876e-7 1.633341419756729e-6 5.91431748896313e-7 64769/84289/29117/5928/1107/5371/8396/23774/3622/79837/27154/57459/10000/7994/3066/7157/5608/7862/9219/5931/1108/54815/208/53615/5305/207/2033/3065/5300 29 Epstein.Barr_virus R-HSA-437239 Recycling pathway of L1 42/5894 47/10654 4.810897506167476e-7 1.6494740278596418e-6 5.972733546433747e-7 9252/71/7430/51807/347688/1785/10381/285643/7846/1808/81027/6456/5962/163/6196/1759/6197/8986/161/79861/5594/8650/6714/10376/6195/1213/1211/1175/1173/84617/10382/7277/4478/160/27330/347733/3897/10383/24137/60/84790/7280 42 Epstein.Barr_virus R-HSA-76009 Platelet Aggregation (Plug Formation) 36/5894 39/10654 4.818293002489785e-7 1.6494740278596418e-6 5.972733546433747e-7 5770/5908/11069/2244/3690/2885/9564/7094/6714/2335/1445/2266/2243/2147/2814/5170/6464/5747/3674/1277/150/6850/6654/7450/7066/151/207/54518/2812/152/4352/1398/2811/5906/2815/1278 36 Epstein.Barr_virus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 55/5894 65/10654 4.877915343514125e-7 1.6658317690107702e-6 6.031964809046592e-7 3725/4436/5892/472/5431/5435/5433/2965/5439/672/2967/1386/11198/904/51497/2176/404672/5438/1643/9656/2177/2068/7157/1025/2353/7936/6829/25920/2963/5434/5436/4292/4331/2966/2962/8812/905/1111/2071/55215/5432/6917/5440/8621/902/5430/6749/545/5441/5395/5437/51755/2968/1022/8178 55 Epstein.Barr_virus R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 83/5894 106/10654 6.138106164494768e-7 2.091117523836353e-6 7.571921456901918e-7 374/4738/1212/23208/950/10980/22848/7037/3482/408/10987/6456/185/30011/2885/163/11037/23149/9185/7314/1839/161/25977/10618/8027/1856/8322/2060/2069/1601/6453/8301/1129/9146/6455/4074/10920/26119/29979/6233/7474/6844/1213/1211/29924/1175/6869/1173/6857/409/160/920/22905/2873/7311/1956/8533/8673/50618/51138/9318/685/1080/29978/58513/7316/1950/64708/3267/3949/867/9341/915/917/115548/1861/3575/6845/551/154/10254/6457/50813 83 Epstein.Barr_virus R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 24/5894 24/10654 6.613534694883241e-7 2.2314732171944172e-6 8.08014840924773e-7 2237/1763/5982/5422/6117/10714/5558/6118/3978/5557/5985/5984/23649/5424/54107/5425/5111/6119/5427/5983/56655/57804/5426/5981 24 Epstein.Barr_virus R-HSA-5260271 Diseases of Immune System 24/5894 24/10654 6.613534694883241e-7 2.2314732171944172e-6 8.08014840924773e-7 4790/10333/4792/929/51135/7187/3551/8517/5970/7096/4791/81793/7098/695/81622/23643/1147/7099/4615/7100/114609/948/7097/148022 24 Epstein.Barr_virus R-HSA-5602358 Diseases associated with the TLR signaling cascade 24/5894 24/10654 6.613534694883241e-7 2.2314732171944172e-6 8.08014840924773e-7 4790/10333/4792/929/51135/7187/3551/8517/5970/7096/4791/81793/7098/695/81622/23643/1147/7099/4615/7100/114609/948/7097/148022 24 Epstein.Barr_virus R-HSA-933542 TRAF6 mediated NF-kB activation 24/5894 24/10654 6.613534694883241e-7 2.2314732171944172e-6 8.08014840924773e-7 4790/4792/177/64135/3551/6283/4214/28512/8517/5970/23586/84282/4791/351/7706/7189/28511/1147/7186/57506/4793/3146/6288/6285 24 Epstein.Barr_virus R-HSA-159227 Transport of the SLBP independent Mature mRNA 32/5894 34/10654 6.924959959274453e-7 2.3088669816822643e-6 8.360390671710738e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10482/8086/22916/81929/9631/79023/23636/4686/53371/9688/10189/8480 32 Epstein.Barr_virus R-HSA-165054 Rev-mediated nuclear export of HIV RNA 32/5894 34/10654 6.924959959274453e-7 2.3088669816822643e-6 8.360390671710738e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/5902/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/1104/5905/81929/9631/79023/23636/53371/9688/8480 32 Epstein.Barr_virus R-HSA-4085377 SUMOylation of SUMOylation proteins 32/5894 34/10654 6.924959959274453e-7 2.3088669816822643e-6 8.360390671710738e-7 23165/348995/6613/57122/23511/23279/23225/9972/8021/55746/51588/10762/79902/9883/6396/129401/4928/5903/55706/7175/10210/4927/8086/7329/81929/9631/79023/23636/53371/9688/7341/8480 32 Epstein.Barr_virus R-HSA-5693537 Resolution of D-Loop Structures 32/5894 34/10654 6.924959959274453e-7 2.3088669816822643e-6 8.360390671710738e-7 83990/5892/9156/1763/7486/472/80198/4683/672/348654/5888/116028/197342/7517/84464/80010/7516/580/641/10524/5889/79728/146956/51750/10111/675/79008/10635/23514/5932/7156/5890 32 Epstein.Barr_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 32/5894 34/10654 6.924959959274453e-7 2.3088669816822643e-6 8.360390671710738e-7 7321/9140/9474/3093/64135/83737/7187/1540/7314/29110/9636/8887/7323/23586/7128/3661/51191/6233/55593/84282/54476/7706/9246/7311/7318/5094/9641/57506/7316/7322/54941/5300 32 Epstein.Barr_virus R-HSA-442755 Activation of NMDA receptors and postsynaptic events 74/5894 93/10654 7.955705675608397e-7 2.6462595474186794e-6 9.582086716422704e-7 5563/4893/51807/817/347688/53632/10381/107/7846/81027/1739/6196/6197/3845/3265/814/5879/5923/818/57554/79861/5567/5594/51422/2892/5573/2902/6714/10376/6195/5613/801/2891/4747/57576/805/5170/84617/3838/8573/2904/2890/10382/5568/7277/10645/55327/5566/84254/5571/27330/347733/3084/816/5577/5562/10383/84790/5564/5565/7280/5595/815/28964/5575/114/5576/4137/2066/1742/88/1385/808/8536 74 Epstein.Barr_virus R-HSA-111996 Ca-dependent events 35/5894 38/10654 8.081846656946496e-7 2.6755666461938166e-6 9.688207509503663e-7 817/5578/5582/107/814/818/5567/5594/112/5573/111/5613/5580/5153/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5321/5575/114/108/5576/1385/808 35 Epstein.Barr_virus R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 35/5894 38/10654 8.081846656946496e-7 2.6755666461938166e-6 9.688207509503663e-7 5908/1265/3313/6175/3936/5898/3181/4001/4282/5062/1072/6627/9049/27250/9987/3185/3458/5478/302/552900/6775/9446/4478/998/6648/2939/6888/3586/829/5055/6647/6950/4507/375/5721 35 Epstein.Barr_virus R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 38/5894 42/10654 8.288859805280063e-7 2.723885667266724e-6 9.863170335967487e-7 9070/5929/6657/324/6932/90780/25776/6659/7314/51176/8945/6662/7534/7091/83439/9580/6233/7514/7089/331/4221/7090/283149/6934/607/7088/208/57680/7311/55553/1487/1499/207/8085/7316/64321/3065/26108 38 Epstein.Barr_virus R-HSA-162588 Budding and maturation of HIV virion 28/5894 29/10654 8.324597277360989e-7 2.723885667266724e-6 9.863170335967487e-7 51652/27243/55048/51271/23327/29082/27183/92421/7314/137492/25978/51160/10015/91782/79720/51534/89853/51510/5478/6233/79643/128866/7311/93343/7251/155382/7316/9525 28 Epstein.Barr_virus R-HSA-5654732 Negative regulation of FGFR3 signaling 28/5894 29/10654 8.324597277360989e-7 2.723885667266724e-6 9.863170335967487e-7 2250/8569/2885/5518/2253/7314/5515/8823/5594/8074/2249/6714/2247/6233/2246/5781/673/7311/5595/5516/10253/8817/2254/7316/26281/10818/2261/867 28 Epstein.Barr_virus R-HSA-72086 mRNA Capping 28/5894 29/10654 8.324597277360989e-7 2.723885667266724e-6 9.863170335967487e-7 5431/5435/5433/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/4686/8731/5437/2968/1022 28 Epstein.Barr_virus R-HSA-933541 TRAF6 mediated IRF7 activation 28/5894 29/10654 8.324597277360989e-7 2.723885667266724e-6 9.863170335967487e-7 3443/3442/80143/1387/64135/3445/29110/3444/23586/3451/3448/3661/3439/10010/84282/3452/3446/3665/7706/3440/7189/9641/3456/3441/7186/57506/3449/2033 28 Epstein.Barr_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 53/5894 63/10654 1.1562719300088158e-6 3.774651056896529e-6 1.366798422577279e-6 55718/4790/5435/4792/3428/1387/22954/1660/3551/7314/11035/8737/29110/81844/28512/8517/6778/51428/5970/3661/6233/661/11128/4791/9533/3665/5434/23220/7098/9208/5591/7311/81030/10621/2547/28511/1147/170506/5440/6737/1499/7520/147945/5441/51082/4615/7316/55703/4793/5437/2033/11277/148022 53 Epstein.Barr_virus R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 31/5894 33/10654 1.1834417373787047e-6 3.8190424873666e-6 1.3828725275019146e-6 23165/348995/57122/23511/23279/23225/9972/8021/55746/3303/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/3304/81929/9631/79023/23636/53371/9688/8480 31 Epstein.Barr_virus R-HSA-180746 Nuclear import of Rev protein 31/5894 33/10654 1.1834417373787047e-6 3.8190424873666e-6 1.3828725275019146e-6 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/1104/3837/81929/9631/79023/23636/53371/9688/8480 31 Epstein.Barr_virus R-HSA-180910 Vpr-mediated nuclear import of PICs 31/5894 33/10654 1.1834417373787047e-6 3.8190424873666e-6 1.3828725275019146e-6 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/11168/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/3159/79023/23636/53371/9688/8815/8480 31 Epstein.Barr_virus R-HSA-389356 CD28 co-stimulation 31/5894 33/10654 1.1834417373787047e-6 3.8190424873666e-6 1.3828725275019146e-6 5295/941/2534/2885/2475/5062/5879/1326/5290/57761/9020/6714/10000/7525/7409/3932/940/253260/5170/64223/8503/4067/5063/998/208/79109/5058/9402/207/942/5296 31 Epstein.Barr_virus R-HSA-5693568 Resolution of D-loop Structures through Holliday Junction Intermediates 31/5894 33/10654 1.1834417373787047e-6 3.8190424873666e-6 1.3828725275019146e-6 83990/5892/9156/1763/7486/472/80198/4683/672/348654/5888/116028/197342/7517/84464/80010/7516/580/641/10524/5889/79728/146956/10111/675/79008/10635/23514/5932/7156/5890 31 Epstein.Barr_virus R-HSA-112409 RAF-independent MAPK1/3 activation 23/5894 23/10654 1.1975555670465631e-6 3.838179231969281e-6 1.3898019289066933e-6 1844/1850/1848/1852/5605/3717/1847/3569/3572/1849/5594/983/80824/1843/3570/7297/5781/8682/1846/11221/3716/5595/5604 23 Epstein.Barr_virus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 23/5894 23/10654 1.1975555670465631e-6 3.838179231969281e-6 1.3898019289066933e-6 11065/7321/8697/51529/29945/51434/29882/7314/996/983/51433/119504/7324/64682/6233/246184/8881/891/10393/7311/25906/991/7316 23 Epstein.Barr_virus R-HSA-428930 Thromboxane signalling through TP receptor 23/5894 23/10654 1.1975555670465631e-6 3.838179231969281e-6 1.3898019289066933e-6 2788/2769/2782/2776/2787/10681/2792/2785/2783/2784/2791/6915/2786/54331/59345/51764/94235/55970/2767/2793/9630/2790/10672 23 Epstein.Barr_virus R-HSA-373760 L1CAM interactions 91/5894 119/10654 1.2110680251977626e-6 3.872665253302845e-6 1.4022892923342513e-6 9252/6711/71/7430/1459/51807/347688/1785/1460/10381/8829/4684/3688/1457/285643/5605/7846/3690/1808/81027/6456/1739/3786/6709/5962/163/6196/1759/6197/6334/8986/3312/100133941/5879/6331/6900/6326/161/79861/5594/6327/284217/2260/3672/8650/1272/6714/10376/6195/7410/3685/1213/1211/1175/1173/84617/6323/6712/3674/10382/7277/3678/4478/160/3912/3785/6710/27330/347733/6386/1641/2048/3897/10383/24137/1956/60/84790/5058/7280/5595/6328/5604/10048/11313/3915/3673/1742/287/3680/288 91 Epstein.Barr_virus R-HSA-75067 Processing of Capped Intronless Pre-mRNA 27/5894 28/10654 1.4578468462152278e-6 4.651225652210489e-6 1.6842054506938064e-6 51585/81608/1477/53981/134353/11051/8106/1478/23283/6636/10914/6635/7884/84967/6637/10898/51692/22916/1479/79869/29894/4686/8189/10978/6634/55339/6628 27 Epstein.Barr_virus R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF) 47/5894 55/10654 1.8903118273480473e-6 6.017350092938241e-6 2.178878124402131e-6 79718/10484/3638/5469/6713/1387/6907/4801/9632/6309/10499/23054/85441/7108/31/96764/4598/5465/2222/3157/6667/3156/6604/80205/10654/6721/10802/9453/4800/57678/1595/5901/4047/9871/3837/4802/6720/2194/4597/1717/6256/10498/2224/3422/4520/8648/10427 47 Epstein.Barr_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 30/5894 32/10654 2.018761388452369e-6 6.411731994475132e-6 2.321683526222993e-6 4738/9372/4089/23327/4088/5499/9110/7040/7314/4092/11171/7046/2280/9958/9040/6233/7514/5500/5501/23645/4087/7048/7311/57154/51377/10273/5045/64750/7316/867 30 Epstein.Barr_virus R-HSA-109704 PI3K Cascade 39/5894 44/10654 2.051089448236893e-6 6.499736156912857e-6 2.3535497699067242e-6 5295/2250/5291/9965/2264/2885/8660/9846/2252/2253/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/2246/2251/5781/30849/5170/2322/2263/208/2549/8817/2254/152831/5289/26281/10818/2261/2255/27006/5296 39 Epstein.Barr_virus R-HSA-1250196 SHC1 events in ERBB2 signaling 22/5894 22/10654 2.1683260880175525e-6 6.794732306994869e-6 2.460367662877729e-6 4893/5578/2064/145957/9542/2885/3845/3265/1839/2065/2069/5580/6464/5782/3084/6654/10718/1956/685/1950/2066/5581 22 Epstein.Barr_virus R-HSA-198753 ERK/MAPK targets 22/5894 22/10654 2.1683260880175525e-6 6.794732306994869e-6 2.460367662877729e-6 9252/1848/1432/6196/5518/6197/51231/5515/1849/5594/5528/5519/5598/4208/6195/5600/1846/5595/5516/1845/4205/2002 22 Epstein.Barr_virus R-HSA-2979096 NOTCH2 Activation and Transmission of Signal to the Nucleus 22/5894 22/10654 2.1683260880175525e-6 6.794732306994869e-6 2.460367662877729e-6 182/23385/4853/57534/28514/7314/3714/1272/102/5664/6233/5663/4192/142678/9148/83464/7311/55851/51107/7316/54492/54567 22 Epstein.Barr_virus R-HSA-392170 ADP signalling through P2Y purinoceptor 12 22/5894 22/10654 2.1683260880175525e-6 6.794732306994869e-6 2.460367662877729e-6 2788/64805/2770/2782/2773/2787/10681/2792/2785/2783/2784/2771/2791/2786/54331/59345/51764/94235/55970/346562/2793/2790 22 Epstein.Barr_virus R-HSA-912631 Regulation of signaling by CBL 22/5894 22/10654 2.1683260880175525e-6 6.794732306994869e-6 2.460367662877729e-6 5295/5291/2534/2885/1399/7314/5290/6233/7525/7409/6850/8503/2889/4067/29760/7311/5293/7316/3055/867/1398/5296 22 Epstein.Barr_virus R-HSA-111933 Calmodulin induced events 33/5894 36/10654 2.2591896262214358e-6 7.048070519054456e-6 2.552101246565935e-6 817/5578/5582/107/814/818/5567/112/5573/111/5613/5580/5153/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5575/114/108/5576/1385/808 33 Epstein.Barr_virus R-HSA-111997 CaM pathway 33/5894 36/10654 2.2591896262214358e-6 7.048070519054456e-6 2.552101246565935e-6 817/5578/5582/107/814/818/5567/112/5573/111/5613/5580/5153/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5575/114/108/5576/1385/808 33 Epstein.Barr_virus R-HSA-1236394 Signaling by ERBB4 49/5894 58/10654 2.3016153094216865e-6 7.164541460965294e-6 2.5942752905451705e-6 5295/4893/2670/51741/23385/6776/4734/10413/145957/83737/6868/9542/2885/3845/3265/7314/6387/1839/5290/2065/2069/23118/348/11059/6714/2099/5664/1447/2567/3925/6233/5663/6464/5241/3084/6654/83464/10718/7311/1956/55851/51107/685/7316/1950/9611/2066/6285/1742 49 Epstein.Barr_virus R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 44/5894 51/10654 2.3481383085414426e-6 7.293224282820772e-6 2.6408712474359433e-6 51807/347688/10381/1780/5048/8655/84516/832/636/7846/81027/51164/79861/23299/5870/10376/10540/140735/84617/11258/1783/10382/93661/55860/830/7277/10671/1639/347733/51143/10383/84790/5049/7280/829/22931/1778/5321/5050/1781/22930/25782/10121/51560 44 Epstein.Barr_virus R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 26/5894 27/10654 2.5498763468110636e-6 7.885002241677289e-6 2.8551536191013413e-6 5431/5435/5433/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/5440/902/5430/5441/8731/5437/2968/1022 26 Epstein.Barr_virus R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 26/5894 27/10654 2.5498763468110636e-6 7.885002241677289e-6 2.8551536191013413e-6 5431/5435/5433/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/5440/902/5430/5441/8731/5437/2968/1022 26 Epstein.Barr_virus R-HSA-112382 Formation of RNA Pol II elongation complex 51/5894 61/10654 2.7101254449816223e-6 8.343865429079087e-6 3.0213076479813547e-6 5431/5435/5433/2965/5439/2967/11198/904/51497/4300/80349/404672/5438/2068/1025/23168/55677/7936/6829/123169/25920/85403/2963/5434/5436/9646/79577/4331/2966/2962/4298/8812/905/2071/27125/5432/22916/55840/6917/5440/902/6830/5430/6749/5441/4686/54623/5437/2968/1022/8178 51 Epstein.Barr_virus R-HSA-75955 RNA Polymerase II Transcription Elongation 51/5894 61/10654 2.7101254449816223e-6 8.343865429079087e-6 3.0213076479813547e-6 5431/5435/5433/2965/5439/2967/11198/904/51497/4300/80349/404672/5438/2068/1025/23168/55677/7936/6829/123169/25920/85403/2963/5434/5436/9646/79577/4331/2966/2962/4298/8812/905/2071/27125/5432/22916/55840/6917/5440/902/6830/5430/6749/5441/4686/54623/5437/2968/1022/8178 51 Epstein.Barr_virus R-HSA-6807505 RNA polymerase II transcribes snRNA genes 60/5894 74/10654 2.779522270339961e-6 8.538838066306387e-6 3.0919070991600575e-6 6884/51585/5431/5435/5433/2960/5439/10302/904/65123/55197/2959/79871/5438/6667/29101/23248/1025/7702/6829/2957/2963/5434/26173/5436/26512/6878/55756/58490/2962/51808/8812/129685/905/5452/64859/6880/6908/80237/6619/6882/2961/5432/22916/6618/6877/5440/5430/5451/55174/6617/5441/4686/2958/5437/80789/51593/79035/1022/8178 60 Epstein.Barr_virus R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 29/5894 31/10654 3.437042292177507e-6 1.0490061833175168e-5 3.7984438164491685e-6 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/3837/81929/9631/79023/23636/53371/9688/8480 29 Epstein.Barr_virus R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 29/5894 31/10654 3.437042292177507e-6 1.0490061833175168e-5 3.7984438164491685e-6 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/81929/9631/79023/23636/53371/9688/8480 29 Epstein.Barr_virus R-HSA-1839124 FGFR1 mutant receptor activation 29/5894 31/10654 3.437042292177507e-6 1.0490061833175168e-5 3.7984438164491685e-6 5295/11052/2250/9530/613/6776/11064/2885/9846/2253/7750/8805/26127/5290/8074/2260/2249/399687/2247/2246/2251/6777/1523/9208/6774/6772/11160/2254/26281 29 Epstein.Barr_virus R-HSA-6807878 COPI-mediated anterograde transport 78/5894 101/10654 3.5679403714840863e-6 1.086600022224699e-5 3.9345708357218e-6 6811/6711/11014/51807/347688/5861/10381/1780/8655/84516/832/55738/7846/51226/3630/81027/6709/10652/54732/51164/79861/2801/377/1315/8615/11316/8729/23423/10376/1314/10540/378/26286/26958/140735/10959/84364/22820/84617/11258/6712/1783/10382/93661/55860/830/7277/10671/966/1639/10282/6710/8775/81876/11015/347733/51143/10383/84790/10945/7280/829/1778/51014/1781/10121/2804/57511/10972/381/4905/9276/287/375/64689/288/22818/372 78 Epstein.Barr_virus R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 35/5894 39/10654 3.6637941133442085e-6 1.1133819260205835e-5 4.031547916013634e-6 9134/10528/10576/10574/6468/10564/54461/10693/8877/10575/898/10517/26985/26330/26190/10238/7157/83752/26224/2629/8237/6774/26272/26270/55135/22948/10694/8841/22803/7203/908/6950/3801/55294/6499 35 Epstein.Barr_virus R-HSA-114604 GPVI-mediated activation cascade 32/5894 35/10654 3.7642507351734e-6 1.1389894159976288e-5 4.124272452346182e-6 5295/5777/5291/388/2534/51206/5879/5290/5336/146850/5880/5294/7410/7409/3932/5781/5170/5590/3937/10451/1277/6850/8503/4067/998/387/27040/23533/391/5296/1278/2207 32 Epstein.Barr_virus R-HSA-9615710 Microautophagy 32/5894 35/10654 3.7642507351734e-6 1.1389894159976288e-5 4.124272452346182e-6 51652/27243/5116/55048/51271/3043/29082/3312/11315/92421/7314/137492/25978/51160/10013/91782/79720/89853/123/6233/79643/1068/128866/7311/93343/7251/155382/1080/6035/7316/10226/7431 32 Epstein.Barr_virus R-HSA-111931 PKA-mediated phosphorylation of CREB 21/5894 21/10654 3.925729830391731e-6 1.1752131641193968e-5 4.2554383827762545e-6 107/5567/112/5573/111/5613/196883/115/801/805/5568/113/5566/5577/109/5575/114/108/5576/1385/808 21 Epstein.Barr_virus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 21/5894 21/10654 3.925729830391731e-6 1.1752131641193968e-5 4.2554383827762545e-6 4790/4792/1660/3551/11035/8737/29110/28512/8517/5970/3661/4791/23220/7098/81030/28511/1147/147945/4615/4793/148022 21 Epstein.Barr_virus R-HSA-389513 CTLA4 inhibitory signaling 21/5894 21/10654 3.925729830391731e-6 1.1752131641193968e-5 4.2554383827762545e-6 5526/941/2534/5518/5515/5528/6714/5519/10000/7525/3932/5781/1493/4067/5529/208/5516/5525/207/942/5527 21 Epstein.Barr_virus R-HSA-445144 Signal transduction by L1 21/5894 21/10654 3.925729830391731e-6 1.1752131641193968e-5 4.2554383827762545e-6 1459/1460/8829/4684/3688/1457/5605/3690/5879/5594/2260/7410/3685/3674/3678/3897/1956/5058/5595/5604/3680 21 Epstein.Barr_virus R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 21/5894 21/10654 3.925729830391731e-6 1.1752131641193968e-5 4.2554383827762545e-6 2237/5982/6117/10714/6118/328/3978/5985/5984/5424/54107/5423/5425/5111/6119/5427/5983/56655/57804/5426/5981 21 Epstein.Barr_virus R-HSA-8939211 ESR-mediated signaling 156/5894 223/10654 4.321724626071996e-6 1.291012006132335e-5 4.674745153690571e-6 5295/2788/374/3725/4893/857/7764/7031/2770/27327/10274/5431/5435/5433/1509/5469/1105/4609/1387/8312/2782/5439/192669/10499/1386/4343/3845/904/7392/3265/8877/2773/2787/6387/1839/5290/6801/4316/5594/2069/10681/5481/5438/4313/865/1655/6667/2792/6714/2099/2494/8850/10000/2785/595/2783/2784/2771/7514/1025/2353/26523/801/2791/2957/805/5170/2963/3838/5434/5590/6464/7090/5241/5747/5436/1903/3315/4318/200845/5885/57678/7033/2962/8503/10524/8243/4602/2786/208/3326/23030/6908/1956/5536/3169/858/5432/3480/10728/5595/7528/3727/27161/2354/596/5440/685/54331/4435/2309/9687/59345/8204/5430/207/5451/2625/57690/6722/1027/51764/94235/5441/10735/192670/2100/1950/55970/4314/346562/2289/7391/2958/5437/2793/3320/2033/4846/9126/9166/3065/2002/2066/861/23028/23112/10498/1385/5296/808/3276/8202/8648/2288/2790 156 Epstein.Barr_virus R-HSA-180024 DARPP-32 events 25/5894 26/10654 4.453979734186238e-6 1.3220990476793327e-5 4.787311106698066e-6 5530/5499/5518/5515/84152/5567/5142/5573/5528/5519/801/805/5568/5566/5577/1020/5141/5516/5533/5575/5532/5576/5534/5144/808 25 Epstein.Barr_virus R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 25/5894 26/10654 4.453979734186238e-6 1.3220990476793327e-5 4.787311106698066e-6 83990/5892/9156/1763/7486/472/4683/672/5888/116028/7517/80010/7516/580/641/10524/5889/79728/51750/10111/675/10635/5932/7156/5890 25 Epstein.Barr_virus R-HSA-912694 Regulation of IFNA signaling 25/5894 26/10654 4.453979734186238e-6 1.3220990476793327e-5 4.787311106698066e-6 3443/5777/3442/5770/9021/11274/3445/3444/3451/3448/3439/3452/6773/7297/5781/3446/3455/6772/8651/3440/3454/3716/3456/3441/3449 25 Epstein.Barr_virus R-HSA-381119 Unfolded Protein Response (UPR) 73/5894 94/10654 5.076794903351189e-6 1.5038000903189733e-5 5.445249270298007e-6 5393/10525/1965/2673/1663/23404/5526/811/3576/55738/10130/3309/4801/55062/6347/11340/9820/10488/84699/7094/9114/468/3484/22872/51726/3068/1054/8894/7466/9451/2931/64061/8570/23016/148327/118460/1968/1200/6464/37/5073/7184/7494/118/10897/1051/84447/5611/4800/1639/11015/10954/22926/90993/81501/51010/64764/56915/167227/22894/4000/10113/440/9709/4802/116138/1649/2081/30827/51013/467/54512/7709 73 Epstein.Barr_virus R-HSA-177929 Signaling by EGFR 42/5894 49/10654 5.780581463238281e-6 1.7086718736924918e-5 6.187088518813197e-6 5295/374/4893/5335/55824/6456/6868/30011/2885/3845/3265/10252/5829/7314/1839/5290/8027/2060/2069/102/6714/9146/6455/1445/6233/29924/5781/6464/5782/998/6654/7311/1956/2549/10253/685/58513/7316/1950/867/10254/6457 42 Epstein.Barr_virus R-HSA-2424491 DAP12 signaling 28/5894 30/10654 5.839765163001709e-6 1.7189434276869048e-5 6.2242817416710555e-6 5295/4893/5335/7305/5291/3824/54209/567/2534/2885/3133/3845/3265/5879/5290/5336/7410/3932/6464/3937/10451/6850/22914/695/6654/9402/27040/5296 28 Epstein.Barr_virus R-HSA-5654696 Downstream signaling of activated FGFR2 28/5894 30/10654 5.839765163001709e-6 1.7189434276869048e-5 6.2242817416710555e-6 5295/4893/2250/5335/2885/2252/2253/3845/3265/5290/8823/8074/2249/2248/2247/2246/2251/5781/6464/2263/6654/2549/8817/2254/26281/10818/2255/27006 28 Epstein.Barr_virus R-HSA-111465 Apoptotic cleavage of cellular proteins 34/5894 38/10654 5.981418436385345e-6 1.7569636200405387e-5 6.361952583695213e-6 660/836/324/9414/4001/6709/6093/840/2934/22985/63967/841/100506658/7082/5339/28988/10134/999/5588/5580/839/1828/5747/118/1829/8428/1832/4000/51765/1499/329/4137/7431/6304 34 Epstein.Barr_virus R-HSA-187687 Signalling to ERKs 31/5894 34/10654 6.2565477323750154e-6 1.8339505540524263e-5 6.640721715941901e-6 4893/5605/5898/1432/5603/2885/3845/3265/1399/5594/9261/6714/4914/5600/6300/6464/673/7867/2889/6654/7529/5595/25759/5604/57498/10818/6014/4803/1398/6016/5906 31 Epstein.Barr_virus R-HSA-422356 Regulation of insulin secretion 62/5894 78/10654 6.681206897130556e-6 1.9543571942334082e-5 7.076713290756513e-6 2788/5331/2770/5578/11069/2769/9495/2782/3630/2776/8826/777/2181/6513/2787/5567/1131/10681/112/5573/111/2792/2785/2783/2784/2771/6844/2182/2791/5568/150/6616/5566/775/2864/23236/2641/6514/2786/5577/773/54331/5575/59345/776/51764/94235/114/4082/5330/3790/55970/2778/2767/10768/152/2793/5576/948/5906/9630/2790 62 Epstein.Barr_virus R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 20/5894 20/10654 7.106947738574336e-6 2.0365530485079613e-5 7.374343885668299e-6 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Epstein.Barr_virus R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 20/5894 20/10654 7.106947738574336e-6 2.0365530485079613e-5 7.374343885668299e-6 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Epstein.Barr_virus R-HSA-3232118 SUMOylation of transcription factors 20/5894 20/10654 7.106947738574336e-6 2.0365530485079613e-5 7.374343885668299e-6 9112/6613/7022/6612/4286/6670/51588/7157/668/7158/9063/8554/7020/1029/7329/7021/3090/7341/10401/4193 20 Epstein.Barr_virus R-HSA-418217 G beta:gamma signalling through PLC beta 20/5894 20/10654 7.106947738574336e-6 2.0365530485079613e-5 7.374343885668299e-6 2788/5331/2782/2787/10681/2792/2785/2783/2784/2791/23236/2786/54331/59345/51764/94235/5330/55970/2793/2790 20 Epstein.Barr_virus R-HSA-5213460 RIPK1-mediated regulated necrosis 20/5894 20/10654 7.106947738574336e-6 2.0365530485079613e-5 7.374343885668299e-6 356/7314/11035/8737/841/8797/6233/8772/331/8717/8743/330/8837/197259/7311/8795/7186/355/7316/329 20 Epstein.Barr_virus R-HSA-5218859 Regulated Necrosis 20/5894 20/10654 7.106947738574336e-6 2.0365530485079613e-5 7.374343885668299e-6 356/7314/11035/8737/841/8797/6233/8772/331/8717/8743/330/8837/197259/7311/8795/7186/355/7316/329 20 Epstein.Barr_virus R-HSA-69186 Lagging Strand Synthesis 20/5894 20/10654 7.106947738574336e-6 2.0365530485079613e-5 7.374343885668299e-6 2237/1763/5982/5422/6117/10714/5558/6118/3978/5557/5985/5984/23649/5424/5425/5111/6119/5983/57804/5981 20 Epstein.Barr_virus R-HSA-8876384 Listeria monocytogenes entry into host cells 20/5894 20/10654 7.106947738574336e-6 2.0365530485079613e-5 7.374343885668299e-6 6456/30011/2885/7314/8027/2060/1500/6714/999/9146/6455/6233/4233/7311/79872/1499/7316/867/10254/6457 20 Epstein.Barr_virus R-HSA-8964616 G beta:gamma signalling through CDC42 20/5894 20/10654 7.106947738574336e-6 2.0365530485079613e-5 7.374343885668299e-6 2788/2782/2787/10681/2792/2785/2783/2784/2791/998/2786/5058/54331/59345/9459/51764/94235/55970/2793/2790 20 Epstein.Barr_virus R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 20/5894 20/10654 7.106947738574336e-6 2.0365530485079613e-5 7.374343885668299e-6 22938/1387/4088/4853/9794/388585/2648/55534/3280/84441/8850/2324/10046/59/4855/23493/4851/23462/2033/3516 20 Epstein.Barr_virus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 24/5894 25/10654 7.76888125446914e-6 2.2127157742992066e-5 8.012227843944307e-6 2308/2475/84335/7249/2932/10000/2931/253260/5170/572/4303/6199/64223/208/79109/1147/2309/842/207/1027/1026/3164/1385/4193 24 Epstein.Barr_virus R-HSA-8854691 Interleukin-20 family signaling 24/5894 25/10654 7.76888125446914e-6 2.2127157742992066e-5 8.012227843944307e-6 11009/6776/3717/282618/50604/282617/3588/55801/3718/6777/6773/7297/5781/6775/50616/53833/6774/6772/29949/116379/163702/3716/58985/53832 24 Epstein.Barr_virus R-HSA-9006115 Signaling by NTRK2 (TRKB) 24/5894 25/10654 7.76888125446914e-6 2.2127157742992066e-5 8.012227843944307e-6 5295/627/4893/5335/2534/2885/3845/3265/5879/5290/1795/6714/4909/5781/4908/6464/2904/7074/6654/2549/1020/4915/10818/8851 24 Epstein.Barr_virus R-HSA-8853659 RET signaling 36/5894 41/10654 8.533940120691686e-6 2.425707828245091e-5 8.783470533577407e-6 5295/2674/1796/5335/5291/5578/2668/2885/8660/9846/5623/5290/5567/4902/6714/5598/64096/9260/5781/6464/5568/2675/2676/5566/8503/6654/5293/2549/85358/5909/10818/5979/9048/5296/2887/9046 36 Epstein.Barr_virus R-HSA-5689880 Ub-specific processing proteases 153/5894 220/10654 9.011618030151106e-6 2.5563198726658484e-5 9.256415803465907e-6 5689/5682/79594/10474/84196/7375/9817/91833/6478/3091/143471/5705/11274/55031/8239/5709/5695/4792/11047/4609/4194/4089/5711/4088/5683/408/64135/5699/8312/5702/8900/8975/57599/377630/6881/51616/1540/80351/5696/5691/7314/5718/6314/90865/2648/5700/122706/5707/8737/55611/57646/23198/63967/83844/9101/8517/993/890/7417/4092/1643/9861/23586/81847/64426/7046/6502/5698/9146/5692/5713/5710/10454/219333/7157/10869/9958/8313/5719/6233/9804/23770/8607/7874/10600/23326/93624/8237/4303/409/330/84101/5706/27005/7416/5423/25862/9738/8658/84132/5714/79589/55288/27430/5688/9097/5687/8078/5708/4087/63891/7189/5704/7311/367/29761/5694/9960/23358/23032/5684/8295/5720/7186/6885/991/5690/2625/5717/9491/4086/1080/57695/10197/64750/7316/10213/8678/9100/5715/3416/5701/329/9099/5685/5686/5728/5716/5693/154/10254/5721/4193 153 Epstein.Barr_virus R-HSA-186763 Downstream signal transduction 27/5894 29/10654 9.9005729456834e-6 2.780460306302703e-5 1.0068026695473822e-5 5295/4893/5335/5291/6776/2885/8440/9564/3845/3265/1399/5290/5921/6778/6714/6777/5781/6774/6772/2889/5159/6654/4690/1398/5155/5296/5156 27 Epstein.Barr_virus R-HSA-5218920 VEGFR2 mediated vascular permeability 27/5894 29/10654 9.9005729456834e-6 2.780460306302703e-5 1.0068026695473822e-5 857/2475/5062/5879/57761/1500/10000/3728/7410/7409/801/253260/805/5170/10451/64223/1003/5063/208/79109/5058/1495/1499/207/3320/4846/808 27 Epstein.Barr_virus R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 27/5894 29/10654 9.9005729456834e-6 2.780460306302703e-5 1.0068026695473822e-5 5431/5435/5433/55124/84944/5439/11022/91646/5438/56165/54514/5434/5436/122402/221400/143689/5432/4603/5440/8468/5430/5441/5437/3320/54456/9271/136991 27 Epstein.Barr_virus R-HSA-8863795 Downregulation of ERBB2 signaling 27/5894 29/10654 9.9005729456834e-6 2.780460306302703e-5 1.0068026695473822e-5 2064/145957/4145/9542/7314/1839/2065/2069/9101/10000/6233/5782/10193/3084/208/10718/7311/1956/11140/8065/685/10273/207/7316/1950/3320/2066 27 Epstein.Barr_virus R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 27/5894 29/10654 9.9005729456834e-6 2.780460306302703e-5 1.0068026695473822e-5 2308/84676/4089/4088/3630/56729/2538/181/847/3484/5443/3066/5105/4303/23410/4287/2908/4852/6648/4087/25942/2309/6720/114907/3065/91584/10891 27 Epstein.Barr_virus R-HSA-113418 Formation of the Early Elongation Complex 30/5894 33/10654 1.0371957899189075e-5 2.8840602300709542e-5 1.0443161271494719e-5 5431/5435/5433/2965/5439/2967/51497/404672/5438/2068/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/4686/5437/2968/1022 30 Epstein.Barr_virus R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 30/5894 33/10654 1.0371957899189075e-5 2.8840602300709542e-5 1.0443161271494719e-5 5431/5435/5433/2965/5439/2967/51497/404672/5438/2068/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/4686/5437/2968/1022 30 Epstein.Barr_virus R-HSA-202433 Generation of second messenger molecules 30/5894 33/10654 1.0371957899189075e-5 2.8840602300709542e-5 1.0443161271494719e-5 5335/3115/3113/3117/3127/5062/3126/916/3702/3932/3120/3937/3123/3122/920/5063/7535/3125/5058/55740/9402/4690/3119/919/27040/915/917/51466/7408/7454 30 Epstein.Barr_virus R-HSA-2871809 FCERI mediated Ca+2 mobilization 30/5894 33/10654 1.0371957899189075e-5 2.8840602300709542e-5 1.0443161271494719e-5 5335/5530/2885/7294/4773/5336/7410/7409/3702/801/805/6464/2205/4772/3937/4775/10451/2206/6850/4067/695/6654/7006/9402/5532/10768/27040/5534/808/2207 30 Epstein.Barr_virus R-HSA-5654726 Negative regulation of FGFR1 signaling 30/5894 33/10654 1.0371957899189075e-5 2.8840602300709542e-5 1.0443161271494719e-5 2250/8569/2885/5518/2253/7314/5515/5594/8074/2260/2249/6714/2248/2247/6233/2246/2251/5781/673/7311/5595/5516/10253/2254/7316/26281/10818/867/2255/27006 30 Epstein.Barr_virus R-HSA-195721 Signaling by WNT 221/5894 331/10654 1.0765930538117645e-5 2.9877049836551334e-5 1.0818458175955443e-5 2788/8454/27123/9070/5689/2780/5158/857/5579/5682/5331/1459/5526/1452/5578/1212/5929/5582/27327/1460/55737/143471/5705/6657/2775/8452/5530/55366/5709/9978/5695/1457/9559/4609/5881/5711/1387/5683/324/5699/8312/2782/5702/192669/57216/1855/6932/90780/163/5518/4343/5593/25776/3845/6659/80351/5696/5691/4920/7314/5879/5515/2787/5718/51176/8945/2535/7476/161/6662/51701/5700/122706/5707/1856/1454/8322/23198/10681/9101/7471/7534/5528/7091/89780/51699/83439/8323/2792/59349/9861/81847/5519/2932/440193/9580/7481/5698/5880/5692/6422/5713/2785/2783/23002/2784/5710/8313/5719/6233/7474/84870/1857/7514/1213/1211/7855/7089/331/8607/1175/26523/801/2791/7976/4221/805/123169/5145/1173/144165/7090/6597/864/4772/409/79577/283149/5706/160/23401/8658/5714/6934/10524/5688/5687/5148/4919/607/23236/5708/5529/7088/2786/208/57680/5704/7311/387/5694/55553/5516/57154/27161/815/5684/8295/5720/7472/54331/7015/6885/1487/1499/5525/59345/139285/207/8085/5690/5532/57690/5717/9491/50855/6500/51764/94235/5330/10197/192670/64750/7316/10213/55970/64321/5216/5715/5701/2793/1455/5685/5686/2033/54894/5534/3065/23112/23513/5527/1488/5716/23072/26108/808/5693/5721/6259/2790/5592 221 Epstein.Barr_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 19/5894 19/10654 1.2865087523359672e-5 3.521629989371023e-5 1.2751796766959002e-5 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Epstein.Barr_virus R-HSA-163615 PKA activation 19/5894 19/10654 1.2865087523359672e-5 3.521629989371023e-5 1.2751796766959002e-5 107/5567/112/5573/111/196883/115/801/805/5568/113/5566/5577/109/5575/114/108/5576/808 19 Epstein.Barr_virus R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 19/5894 19/10654 1.2865087523359672e-5 3.521629989371023e-5 1.2751796766959002e-5 11065/7321/8697/51529/29945/51434/29882/996/51433/119504/7324/64682/246184/8881/10393/51343/25906/991/8556 19 Epstein.Barr_virus R-HSA-176412 Phosphorylation of the APC/C 19/5894 19/10654 1.2865087523359672e-5 3.521629989371023e-5 1.2751796766959002e-5 11065/7321/8697/51529/29945/51434/29882/996/983/51433/119504/7324/64682/246184/8881/891/10393/25906/5347 19 Epstein.Barr_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 19/5894 19/10654 1.2865087523359672e-5 3.521629989371023e-5 1.2751796766959002e-5 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Epstein.Barr_virus R-HSA-77595 Processing of Intronless Pre-mRNAs 19/5894 19/10654 1.2865087523359672e-5 3.521629989371023e-5 1.2751796766959002e-5 51585/81608/1477/53981/11051/8106/1478/23283/10914/10898/51692/22916/1479/79869/29894/4686/8189/10978/55339 19 Epstein.Barr_virus R-HSA-8851708 Signaling by FGFR2 IIIa TM 19/5894 19/10654 1.2865087523359672e-5 3.521629989371023e-5 1.2751796766959002e-5 5431/5435/5433/5439/5438/2247/2246/2963/5434/5436/2263/2962/5432/22916/5440/5430/5441/4686/5437 19 Epstein.Barr_virus R-HSA-3371571 HSF1-dependent transactivation 23/5894 24/10654 1.3530203810886044e-5 3.668014790350032e-5 1.3281855074472864e-5 817/3305/1387/2475/3306/3312/818/3303/84335/3337/3297/57521/1410/64223/26353/816/3326/3304/10728/815/3320/2033/2288 23 Epstein.Barr_virus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 23/5894 24/10654 1.3530203810886044e-5 3.668014790350032e-5 1.3281855074472864e-5 1432/3654/7334/7314/257397/5606/8767/23118/8517/9261/10454/6233/5600/5608/7867/64127/3656/7189/7311/6885/10392/7316/7335 23 Epstein.Barr_virus R-HSA-452723 Transcriptional regulation of pluripotent stem cells 23/5894 24/10654 1.3530203810886044e-5 3.668014790350032e-5 1.3281855074472864e-5 6299/64344/79727/6657/55211/4089/27022/2516/5460/2041/5087/2247/63978/2649/6774/9314/79923/4087/2034/7547/6997/27086/57167 23 Epstein.Barr_virus R-HSA-5627123 RHO GTPases activate PAKs 23/5894 24/10654 1.3530203810886044e-5 3.668014790350032e-5 1.3281855074472864e-5 2017/79784/4628/5062/5879/4638/4659/4771/801/5500/805/2316/10627/5063/998/5058/4629/3984/4627/10398/4637/103910/808 23 Epstein.Barr_virus R-HSA-982772 Growth hormone receptor signaling 23/5894 24/10654 1.3530203810886044e-5 3.668014790350032e-5 1.3281855074472864e-5 5777/5770/9021/6776/3717/5618/6868/8660/1154/3667/2690/5594/5617/8835/6777/6774/6772/8651/1442/4067/2689/5595/2688 23 Epstein.Barr_virus R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 26/5894 28/10654 1.6746259854556928e-5 4.5167305571037416e-5 1.6355048738549443e-5 10381/10576/7846/7411/81027/10574/10693/5201/5204/10575/10471/5202/84617/10382/7277/347733/10383/60/84790/22948/7280/10694/5203/7203/908/6950 26 Epstein.Barr_virus R-HSA-69205 G1/S-Specific Transcription 26/5894 28/10654 1.6746259854556928e-5 4.5167305571037416e-5 1.6355048738549443e-5 5422/1869/4998/5928/990/8900/6241/7027/898/5934/1876/983/7298/7029/1719/26271/8318/286826/5111/1874/81620/55957/1875/5933/3065/7083 26 Epstein.Barr_virus R-HSA-5654736 Signaling by FGFR1 42/5894 50/10654 1.675716667241047e-5 4.5167305571037416e-5 1.6355048738549443e-5 5295/4893/2250/5335/8569/2885/5518/2253/3845/3265/7314/5515/5290/5594/8074/2260/2249/6714/2248/2247/6233/2246/2251/200734/5781/6464/673/6654/7311/2549/5595/5516/10253/8817/2254/7316/26281/10818/867/2255/27006/161742 42 Epstein.Barr_virus R-HSA-1251985 Nuclear signaling by ERBB4 29/5894 32/10654 1.714709102818731e-5 4.577980469954373e-5 1.6576834230785294e-5 2670/51741/23385/6776/10413/145957/6868/9542/6387/1839/2069/23118/348/6714/2099/5664/1447/3925/5663/5241/3084/83464/10718/55851/51107/685/9611/2066/6285 29 Epstein.Barr_virus R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 29/5894 32/10654 1.714709102818731e-5 4.577980469954373e-5 1.6576834230785294e-5 51807/10381/10576/7846/7411/81027/10574/10693/5201/79861/5204/10575/10471/10376/5202/84617/10382/7277/347733/10383/60/84790/22948/7280/10694/5203/7203/908/6950 29 Epstein.Barr_virus R-HSA-5626467 RHO GTPases activate IQGAPs 29/5894 32/10654 1.714709102818731e-5 4.577980469954373e-5 1.6576834230785294e-5 71/6249/51807/347688/10381/7846/81027/8826/5879/79861/999/10376/128239/801/4221/805/84617/10382/7277/347733/998/10788/10383/60/84790/7280/1495/1499/808 29 Epstein.Barr_virus R-HSA-8941326 RUNX2 regulates bone development 29/5894 32/10654 1.714709102818731e-5 4.577980469954373e-5 1.6576834230785294e-5 5925/9759/10413/4089/3549/25/5594/3280/100526737/10013/2737/865/6714/7525/10432/4091/1277/2736/23493/367/860/5595/8841/23462/4086/4094/23314/25925/25937 29 Epstein.Barr_virus R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 29/5894 32/10654 1.714709102818731e-5 4.577980469954373e-5 1.6576834230785294e-5 5295/5777/84876/2534/30011/2885/973/933/6786/80228/5336/7409/118788/801/805/930/7220/6850/4067/29760/695/6654/5293/27071/4690/640/10768/974/808 29 Epstein.Barr_virus R-HSA-3247509 Chromatin modifying enzymes 185/5894 274/10654 2.0244591479128975e-5 5.3845255597607685e-5 1.9497328178088596e-5 9643/9070/1810/4790/79718/64769/51742/79595/80314/10474/9112/10445/5929/79813/7403/54556/23338/84289/9612/6603/5926/9767/27097/5928/1387/56950/3717/6907/23512/1107/79084/10943/57492/23133/22992/26610/6881/10499/1386/9575/55689/3054/51230/10284/55257/8089/55170/54014/23774/84661/8464/9869/6314/196528/2648/23186/55869/84193/2146/1788/51147/6871/23569/86/83933/5970/51562/51412/64426/79685/8850/55352/27154/57459/6604/8289/84159/56943/6602/55929/595/7994/6944/8473/23522/3066/23067/79918/10419/8607/8726/6883/51780/10765/4791/55193/55904/55683/84678/6595/1019/5927/29943/23326/54859/84148/7862/6597/93624/9219/5931/8520/6599/11240/8819/54496/56970/11143/63976/1108/2122/84444/10524/55578/64324/54815/23210/9682/339287/55693/57504/58508/23030/57634/6880/60/6601/6187/53615/10362/4297/55140/121536/10196/8295/8841/55167/55250/11091/8242/5978/8085/6839/25855/284058/6598/117143/10629/79960/55870/9611/2874/10856/29072/10933/80853/2033/6605/221656/3065/23028/23135/10498/9757/80854/51317/9739/10902/3276/55729/9913/8648/64754/10919/54934 185 Epstein.Barr_virus R-HSA-4839726 Chromatin organization 185/5894 274/10654 2.0244591479128975e-5 5.3845255597607685e-5 1.9497328178088596e-5 9643/9070/1810/4790/79718/64769/51742/79595/80314/10474/9112/10445/5929/79813/7403/54556/23338/84289/9612/6603/5926/9767/27097/5928/1387/56950/3717/6907/23512/1107/79084/10943/57492/23133/22992/26610/6881/10499/1386/9575/55689/3054/51230/10284/55257/8089/55170/54014/23774/84661/8464/9869/6314/196528/2648/23186/55869/84193/2146/1788/51147/6871/23569/86/83933/5970/51562/51412/64426/79685/8850/55352/27154/57459/6604/8289/84159/56943/6602/55929/595/7994/6944/8473/23522/3066/23067/79918/10419/8607/8726/6883/51780/10765/4791/55193/55904/55683/84678/6595/1019/5927/29943/23326/54859/84148/7862/6597/93624/9219/5931/8520/6599/11240/8819/54496/56970/11143/63976/1108/2122/84444/10524/55578/64324/54815/23210/9682/339287/55693/57504/58508/23030/57634/6880/60/6601/6187/53615/10362/4297/55140/121536/10196/8295/8841/55167/55250/11091/8242/5978/8085/6839/25855/284058/6598/117143/10629/79960/55870/9611/2874/10856/29072/10933/80853/2033/6605/221656/3065/23028/23135/10498/9757/80854/51317/9739/10902/3276/55729/9913/8648/64754/10919/54934 185 Epstein.Barr_virus R-HSA-73933 Resolution of Abasic Sites (AP sites) 34/5894 39/10654 2.174126383306538e-5 5.7716902288911305e-5 2.089924864985828e-5 2237/4350/4913/5982/8505/6117/10714/6118/328/3978/5985/5984/4595/5424/7515/54107/5423/5425/5111/6119/5427/142/4968/3980/5983/10038/56655/11284/57804/6996/5426/8930/5981/7374 34 Epstein.Barr_virus R-HSA-1368082 RORA activates gene expression 18/5894 18/10654 2.3286771766244618e-5 6.112777588639212e-5 2.2134323517011773e-5 79718/5469/1387/6907/10499/23054/85441/96764/5465/6604/80205/1374/6095/6720/2033/6256/10498/8648 18 Epstein.Barr_virus R-HSA-1912420 Pre-NOTCH Processing in Golgi 18/5894 18/10654 2.3286771766244618e-5 6.112777588639212e-5 2.2134323517011773e-5 6400/4853/6487/487/4854/5870/10959/4242/10402/5986/489/4855/4851/5045/3955/488/6484/2683 18 Epstein.Barr_virus R-HSA-5675482 Regulation of necroptotic cell death 18/5894 18/10654 2.3286771766244618e-5 6.112777588639212e-5 2.2134323517011773e-5 356/7314/8737/841/8797/6233/8772/331/8717/8743/330/8837/7311/8795/7186/355/7316/329 18 Epstein.Barr_virus R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 18/5894 18/10654 2.3286771766244618e-5 6.112777588639212e-5 2.2134323517011773e-5 2810/6790/1647/7027/5934/983/7157/7029/891/5111/1874/25946/5933/2033/995/10498/581/3276 18 Epstein.Barr_virus R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 18/5894 18/10654 2.3286771766244618e-5 6.112777588639212e-5 2.2134323517011773e-5 4893/5578/2885/6196/6197/3845/3265/1839/5594/5598/6195/2520/887/6654/1956/5595/4314/1385 18 Epstein.Barr_virus R-HSA-8964315 G beta:gamma signalling through BTK 18/5894 18/10654 2.3286771766244618e-5 6.112777588639212e-5 2.2134323517011773e-5 2788/2782/2787/10681/2792/2785/2783/2784/2791/695/2786/54331/59345/51764/94235/55970/2793/2790 18 Epstein.Barr_virus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 22/5894 23/10654 2.3525277549379302e-5 6.141014009643169e-5 2.2236567393613083e-5 3654/7334/7314/257397/5601/8767/23118/8517/10454/6233/64127/5602/3656/7189/7311/6416/6885/10392/7316/7335/5609/5599 22 Epstein.Barr_virus R-HSA-5654695 PI-3K cascade:FGFR2 22/5894 23/10654 2.3525277549379302e-5 6.141014009643169e-5 2.2236567393613083e-5 5295/2250/2885/2252/2253/5290/8823/8074/2249/2248/2247/2246/2251/5781/2263/2549/8817/2254/26281/10818/2255/27006 22 Epstein.Barr_virus R-HSA-5654699 SHC-mediated cascade:FGFR2 22/5894 23/10654 2.3525277549379302e-5 6.141014009643169e-5 2.2236567393613083e-5 4893/2250/2885/2252/2253/3845/3265/8823/8074/2249/2248/2247/2246/2251/6464/2263/6654/8817/2254/26281/2255/27006 22 Epstein.Barr_virus R-HSA-1632852 Macroautophagy 72/5894 95/10654 2.689533588713126e-5 7.007729183924757e-5 2.5374936782400642e-5 51652/5563/65018/1459/27243/9140/8878/1460/53632/9474/8655/1457/29082/55054/55062/2475/84557/3312/92421/7314/64422/139341/25978/9821/51422/7249/10533/91782/192111/440738/6714/8408/123/55669/6233/9804/30849/57521/140735/28956/7405/79643/389541/22863/7416/26100/64223/5571/128866/6009/55004/7311/5562/55626/5564/5565/7248/11337/10452/64419/7316/83734/11152/5289/8678/56993/10226/8649/81631/10542/23710/54543 72 Epstein.Barr_virus R-HSA-1489509 DAG and IP3 signaling 36/5894 42/10654 2.7809037700616006e-5 7.232405923247082e-5 2.618848963342377e-5 5335/817/5578/5582/107/814/818/5567/112/5573/111/5613/5580/5153/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5575/114/108/10768/5576/1385/5581/808 36 Epstein.Barr_virus R-HSA-1538133 G0 and Early G1 25/5894 27/10654 2.825527207637576e-5 7.307935259459687e-5 2.646198081456243e-5 9134/1869/4609/5928/990/8900/7027/7153/898/5934/993/890/983/7029/1859/286826/5111/1874/55957/1017/4605/4149/1875/5933/3065 25 Epstein.Barr_virus R-HSA-164952 The role of Nef in HIV-1 replication and disease pathogenesis 25/5894 27/10654 2.825527207637576e-5 7.307935259459687e-5 2.646198081456243e-5 162/1174/567/2534/163/1794/5062/5879/161/10053/926/3932/1175/8907/940/1173/160/920/8905/164/919/130340/3055/9844/375 25 Epstein.Barr_virus R-HSA-5654716 Downstream signaling of activated FGFR4 25/5894 27/10654 2.825527207637576e-5 7.307935259459687e-5 2.646198081456243e-5 5295/4893/5335/9965/2264/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/2251/5781/6464/6654/2549/8817/2254/152831/26281/10818 25 Epstein.Barr_virus R-HSA-5619084 ABC transporter disorders 60/5894 77/10654 2.930141457948771e-5 7.564603727218203e-5 2.73913754832874e-5 5244/5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/5696/5691/7314/5718/5700/122706/5707/10956/79139/91445/64241/23198/9861/5698/5692/5713/5710/5719/6233/10058/5706/19/335/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 60 Epstein.Barr_virus R-HSA-5689896 Ovarian tumor domain proteases 33/5894 38/10654 3.452714761760936e-5 8.89738034761472e-5 3.221735000370721e-5 7321/324/64135/7187/7314/8737/8767/55611/8517/80124/983/2099/23586/7128/7157/6233/55593/84282/10318/7706/79155/79589/64127/7189/7311/387/56957/10392/57506/7316/7415/5728/78990 33 Epstein.Barr_virus R-HSA-113510 E2F mediated regulation of DNA replication 21/5894 22/10654 4.083120842024956e-5 1.0407519972335349e-4 3.768555468230509e-5 5925/5422/1869/84515/4998/5518/5001/5558/5515/23594/7027/5557/983/5519/7029/23649/4999/5000/891/23595/5516 21 Epstein.Barr_virus R-HSA-202427 Phosphorylation of CD3 and TCR zeta chains 21/5894 22/10654 4.083120842024956e-5 1.0407519972335349e-4 3.768555468230509e-5 5788/3115/3113/3117/55824/26191/3127/3126/1445/916/3932/3120/3123/3122/920/5795/3125/3119/919/915/917 21 Epstein.Barr_virus R-HSA-5655332 Signaling by FGFR3 in disease 21/5894 22/10654 4.083120842024956e-5 1.0407519972335349e-4 3.768555468230509e-5 5295/4893/2250/5335/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/6654/2549/8817/2254/26281/10818/2261 21 Epstein.Barr_virus R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 21/5894 22/10654 4.083120842024956e-5 1.0407519972335349e-4 3.768555468230509e-5 5295/4893/2250/5335/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/6654/2549/8817/2254/26281/10818/2261 21 Epstein.Barr_virus R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 21/5894 22/10654 4.083120842024956e-5 1.0407519972335349e-4 3.768555468230509e-5 3725/7531/356/7001/4001/826/823/2801/993/351/6648/1020/4000/994/2309/10018/831/824/995/8851/5052 21 Epstein.Barr_virus R-HSA-8863678 Neurodegenerative Diseases 21/5894 22/10654 4.083120842024956e-5 1.0407519972335349e-4 3.768555468230509e-5 3725/7531/356/7001/4001/826/823/2801/993/351/6648/1020/4000/994/2309/10018/831/824/995/8851/5052 21 Epstein.Barr_virus R-HSA-164378 PKA activation in glucagon signalling 17/5894 17/10654 4.2147590824833056e-5 1.0589582194739306e-4 3.8344800675224056e-5 107/5567/112/5573/111/196883/115/5568/113/5566/5577/109/5575/114/108/2778/5576 17 Epstein.Barr_virus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 17/5894 17/10654 4.2147590824833056e-5 1.0589582194739306e-4 3.8344800675224056e-5 4790/4792/1660/3551/11035/8737/28512/8517/5970/4791/7098/81030/28511/1147/4615/4793/148022 17 Epstein.Barr_virus R-HSA-450385 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA 17/5894 17/10654 4.2147590824833056e-5 1.0589582194739306e-4 3.8344800675224056e-5 5393/23404/11340/9261/23016/118460/677/51010/56915/167227/7529/22894/207/55802/51013/54464/54512 17 Epstein.Barr_virus R-HSA-450513 Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA 17/5894 17/10654 4.2147590824833056e-5 1.0589582194739306e-4 3.8344800675224056e-5 5393/23404/11340/9261/23016/118460/3842/7538/51010/56915/167227/7529/22894/55802/51013/54464/54512 17 Epstein.Barr_virus R-HSA-450604 KSRP (KHSRP) binds and destabilizes mRNA 17/5894 17/10654 4.2147590824833056e-5 1.0589582194739306e-4 3.8344800675224056e-5 5393/23404/1432/11340/7534/5600/8570/23016/118460/5073/51010/56915/167227/22894/207/51013/54512 17 Epstein.Barr_virus R-HSA-5655862 Translesion synthesis by POLK 17/5894 17/10654 4.2147590824833056e-5 1.0589582194739306e-4 3.8344800675224056e-5 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/51426/7311/5983/7316/10459/5981/5980 17 Epstein.Barr_virus R-HSA-5656121 Translesion synthesis by POLI 17/5894 17/10654 4.2147590824833056e-5 1.0589582194739306e-4 3.8344800675224056e-5 5982/6117/7314/6118/11201/51455/5985/5984/6233/5111/6119/7311/5983/7316/10459/5981/5980 17 Epstein.Barr_virus R-HSA-8934593 Regulation of RUNX1 Expression and Activity 17/5894 17/10654 4.2147590824833056e-5 1.0589582194739306e-4 3.8344800675224056e-5 27327/192669/5371/4343/865/6714/595/896/26523/5781/27161/894/57690/192670/1021/861/23112 17 Epstein.Barr_virus R-HSA-499943 Interconversion of nucleotide di- and triphosphates 27/5894 30/10654 4.6447842989818925e-5 1.164921837552143e-4 4.2181735635748865e-5 56474/4832/654364/7295/1841/205/7296/6241/158067/203/2936/4831/102157402/4833/7298/50484/204/2745/1854/2987/51727/26289/1503/6240/4830/122481/79077 27 Epstein.Barr_virus R-HSA-110373 Resolution of AP sites via the multiple-nucleotide patch replacement pathway 24/5894 26/10654 4.754769949786428e-5 1.186163354494593e-4 4.295088943069487e-5 2237/5982/8505/6117/10714/6118/328/3978/5985/5984/5424/54107/5423/5425/5111/6119/5427/142/5983/10038/56655/57804/5426/5981 24 Epstein.Barr_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 24/5894 26/10654 4.754769949786428e-5 1.186163354494593e-4 4.295088943069487e-5 9372/23327/4088/5499/9110/7040/7314/4092/11171/7046/9958/6233/7514/5500/5501/23645/4087/7048/7311/57154/51377/10273/64750/7316 24 Epstein.Barr_virus R-HSA-6803529 FGFR2 alternative splicing 24/5894 26/10654 4.754769949786428e-5 1.186163354494593e-4 4.295088943069487e-5 54845/5431/5435/5433/5439/7072/7073/5438/3185/4670/5725/2963/5434/5436/2962/5432/22916/5440/5430/3178/5441/4686/5437/3187 24 Epstein.Barr_virus R-HSA-5693538 Homology Directed Repair 99/5894 138/10654 4.921513546049017e-5 1.2255875326178703e-4 4.4378436074293884e-5 2237/83990/151987/5892/9156/1763/7486/5982/472/6613/80198/4683/165918/84126/8900/8924/2067/672/6117/7334/10714/348654/83695/7314/6118/25/5888/51588/51720/63967/5531/116028/890/197342/7517/9656/84464/5985/5984/6233/7158/6047/5884/5810/5424/80010/7516/7515/54107/580/11073/5425/641/5111/6119/3364/10524/5427/144715/5889/5429/142/1111/10721/7329/79728/51426/146956/7311/3980/5983/10038/56655/51750/1017/54962/5893/5883/10111/57804/675/51548/545/7336/2072/29086/7316/79008/5426/10635/7341/8914/23514/5932/9025/79184/7156/5890/5981 99 Epstein.Barr_virus R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 96/5894 134/10654 6.947872784352367e-5 1.7271478811985475e-4 6.253990008604323e-5 5579/2153/7042/5175/3959/5578/5582/3082/29106/3920/374354/2244/3309/3690/2162/87/10487/7040/5874/350/7043/967/5054/5099/1072/5340/7094/7414/83706/6810/7123/12/3671/7273/22927/1191/9749/3273/27154/226/2335/5478/94121/22915/2266/7076/2243/801/805/928/351/135228/2316/3674/7277/334/10447/335/308/6403/197/81/9948/3481/5473/8407/7450/29789/10916/5005/7422/5004/5196/3827/1950/2621/5216/5768/710/6647/1893/7078/55664/2/948/88/5341/3479/5155/51368/808/213/5660/7057/5627/6814 96 Epstein.Barr_virus R-HSA-500657 Presynaptic function of Kainate receptors 20/5894 21/10654 7.073130590222662e-5 1.7490148928722818e-4 6.33317030000512e-5 2788/5331/2782/2787/10681/2792/2785/2783/2784/2791/23236/2786/54331/59345/51764/94235/5330/55970/2793/2790 20 Epstein.Barr_virus R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 20/5894 21/10654 7.073130590222662e-5 1.7490148928722818e-4 6.33317030000512e-5 25904/55571/55835/57472/85456/29883/1263/7832/10769/7157/5325/4869/4850/246175/4848/23019/4849/9337/28984/995 20 Epstein.Barr_virus R-HSA-6807004 Negative regulation of MET activity 20/5894 21/10654 7.073130590222662e-5 1.7490148928722818e-4 6.33317030000512e-5 5770/3082/6456/30011/2885/7314/8027/2060/9101/9146/6455/6233/4233/5795/5771/7311/7316/867/10254/6457 20 Epstein.Barr_virus R-HSA-9619483 Activation of AMPK downstream of NMDARs 26/5894 29/10654 7.607554639812696e-5 1.8440567079609747e-4 6.67731602628296e-5 5563/51807/347688/53632/10381/7846/81027/79861/51422/10376/801/805/84617/10382/7277/10645/5571/347733/5562/10383/84790/5564/5565/7280/4137/808 26 Epstein.Barr_virus R-HSA-110312 Translesion synthesis by REV1 16/5894 16/10654 7.627867832503819e-5 1.8440567079609747e-4 6.67731602628296e-5 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/7311/5983/7316/10459/5981/5980 16 Epstein.Barr_virus R-HSA-1295596 Spry regulation of FGF signaling 16/5894 16/10654 7.627867832503819e-5 1.8440567079609747e-4 6.67731602628296e-5 8569/2885/5518/7314/5515/5594/6714/6233/5781/673/7311/5595/5516/10253/7316/867 16 Epstein.Barr_virus R-HSA-175474 Assembly Of The HIV Virion 16/5894 16/10654 7.627867832503819e-5 1.8440567079609747e-4 6.67731602628296e-5 55048/51271/7314/137492/51160/79720/9397/89853/5478/6233/7311/93343/7251/155382/5045/7316 16 Epstein.Barr_virus R-HSA-193639 p75NTR signals via NF-kB 16/5894 16/10654 7.627867832503819e-5 1.8440567079609747e-4 6.67731602628296e-5 4790/8878/4792/3654/3551/7314/8767/5970/6233/7189/7311/4804/5584/4615/7316/4803 16 Epstein.Barr_virus R-HSA-1963640 GRB2 events in ERBB2 signaling 16/5894 16/10654 7.627867832503819e-5 1.8440567079609747e-4 6.67731602628296e-5 4893/2064/145957/9542/2885/3845/3265/1839/2069/3084/6654/10718/1956/685/1950/2066 16 Epstein.Barr_virus R-HSA-1963642 PI3K events in ERBB2 signaling 16/5894 16/10654 7.627867832503819e-5 1.8440567079609747e-4 6.67731602628296e-5 5295/2064/145957/9542/2885/1839/5290/2065/2069/3084/10718/1956/2549/685/1950/2066 16 Epstein.Barr_virus R-HSA-205043 NRIF signals cell death from the nucleus 16/5894 16/10654 7.627867832503819e-5 1.8440567079609747e-4 6.67731602628296e-5 8878/23385/7314/5664/6233/5663/7189/83464/7311/55851/51107/4804/23421/7316/4803/5599 16 Epstein.Barr_virus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 16/5894 16/10654 7.627867832503819e-5 1.8440567079609747e-4 6.67731602628296e-5 7040/7314/50848/7046/2280/6233/57530/5590/7048/7311/387/57154/50855/23370/7316/56288 16 Epstein.Barr_virus R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 16/5894 16/10654 7.627867832503819e-5 1.8440567079609747e-4 6.67731602628296e-5 5295/5291/2534/2885/9846/5290/5170/6464/2205/2206/6850/4067/6654/7462/5296/2207 16 Epstein.Barr_virus R-HSA-399954 Sema3A PAK dependent Axon repulsion 16/5894 16/10654 7.627867832503819e-5 1.8440567079609747e-4 6.67731602628296e-5 5361/8829/2534/2242/5362/5062/5879/1072/10371/55558/5063/3326/5058/3984/3320/91584 16 Epstein.Barr_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 16/5894 16/10654 7.627867832503819e-5 1.8440567079609747e-4 6.67731602628296e-5 8454/4790/3551/7314/8945/1326/8517/6233/79155/7311/6416/1147/5604/6500/7316/23291 16 Epstein.Barr_virus R-HSA-9614657 FOXO-mediated transcription of cell death genes 16/5894 16/10654 7.627867832503819e-5 1.8440567079609747e-4 6.67731602628296e-5 2308/65018/356/1387/4801/604/4303/4800/10370/6794/27113/2309/10018/4802/1649/2033 16 Epstein.Barr_virus R-HSA-1643713 Signaling by EGFR in Cancer 23/5894 25/10654 7.978541320968076e-5 1.9156668325259526e-4 6.936615770340486e-5 5295/374/4893/5335/2885/3845/3265/7314/1839/5290/2069/6233/6464/6654/7311/1956/2549/11140/685/7316/1950/867/3320 23 Epstein.Barr_virus R-HSA-5654700 FRS-mediated FGFR2 signaling 23/5894 25/10654 7.978541320968076e-5 1.9156668325259526e-4 6.936615770340486e-5 4893/2250/2885/2252/2253/3845/3265/8823/8074/2249/2248/2247/2246/2251/5781/2263/6654/8817/2254/26281/10818/2255/27006 23 Epstein.Barr_virus R-HSA-5654708 Downstream signaling of activated FGFR3 23/5894 25/10654 7.978541320968076e-5 1.9156668325259526e-4 6.936615770340486e-5 5295/4893/2250/5335/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/5781/6464/6654/2549/8817/2254/26281/10818/2261 23 Epstein.Barr_virus R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 23/5894 25/10654 7.978541320968076e-5 1.9156668325259526e-4 6.936615770340486e-5 51400/5520/8900/5518/7465/5515/993/890/983/5519/7514/2305/9133/891/4331/5347/5516/1017/994/902/9088/995/1022 23 Epstein.Barr_virus R-HSA-73863 RNA Polymerase I Transcription Termination 28/5894 32/10654 1.0609179179490845e-4 2.542949762443547e-4 9.208002730877015e-5 5435/2965/64425/2967/404672/2068/9533/5434/9015/79101/221830/7270/4331/9013/2966/2071/6908/5440/902/9014/25885/5441/51082/7343/5437/2968/84172/1022 28 Epstein.Barr_virus R-HSA-75153 Apoptotic execution phase 42/5894 52/10654 1.0653411234611675e-4 2.549209116853508e-4 9.230667808005819e-5 10059/660/836/324/9414/4001/3836/6709/6093/840/5062/2934/22985/63967/841/100506658/7082/5339/28988/10134/999/5588/5580/839/1828/5747/118/1829/8428/1832/3148/4000/3837/1676/51765/1499/3146/329/4137/1677/7431/6304 42 Epstein.Barr_virus R-HSA-6806834 Signaling by MET 60/5894 79/10654 1.1255264333238239e-4 2.688651429009542e-4 9.735587413613275e-5 5295/4893/5770/5908/3082/1280/1289/3688/3910/6456/30011/2885/3845/3265/1399/7314/5879/3918/5290/8027/3911/2060/284217/9101/6714/9146/6455/2335/64759/6233/5781/1302/6464/85440/5747/382/1277/3912/6774/4233/5795/2889/5771/3913/6654/5867/7311/2549/53916/10048/7316/3915/3673/867/1398/5906/23163/1278/10254/6457 60 Epstein.Barr_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 19/5894 20/10654 1.2226974343428054e-4 2.8913198153282814e-4 1.0469448177300624e-4 7321/7334/3551/7314/11035/8737/8517/7323/6233/330/7098/7189/7311/1147/7316/7335/7322/329/148022 19 Epstein.Barr_virus R-HSA-5625900 RHO GTPases activate CIT 19/5894 20/10654 1.2226974343428054e-4 2.8913198153282814e-4 1.0469448177300624e-4 388/79784/4628/5879/4659/389/11113/9055/5500/10627/387/4629/4627/1027/10398/4637/1742/9928/103910 19 Epstein.Barr_virus R-HSA-5627117 RHO GTPases Activate ROCKs 19/5894 20/10654 1.2226974343428054e-4 2.8913198153282814e-4 1.0469448177300624e-4 388/79784/9475/4628/6093/1072/4659/389/5500/10627/387/5058/4629/3984/4627/3985/10398/4637/103910 19 Epstein.Barr_virus R-HSA-5654719 SHC-mediated cascade:FGFR4 19/5894 20/10654 1.2226974343428054e-4 2.8913198153282814e-4 1.0469448177300624e-4 4893/9965/2264/2885/2253/3845/3265/8823/8074/2249/2247/2246/2251/6464/6654/8817/2254/152831/26281 19 Epstein.Barr_virus R-HSA-5654720 PI-3K cascade:FGFR4 19/5894 20/10654 1.2226974343428054e-4 2.8913198153282814e-4 1.0469448177300624e-4 5295/9965/2264/2885/2253/5290/8823/8074/2249/2247/2246/2251/5781/2549/8817/2254/152831/26281/10818 19 Epstein.Barr_virus R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 19/5894 20/10654 1.2226974343428054e-4 2.8913198153282814e-4 1.0469448177300624e-4 472/1387/51499/7159/637/27166/23368/7157/63970/55240/5366/84883/147923/94241/8626/7161/665/27113/581 19 Epstein.Barr_virus R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 25/5894 28/10654 1.2416370725819943e-4 2.931180136112191e-4 1.0613782111085927e-4 2788/2770/2782/2787/10681/112/111/2792/2785/2783/2784/2771/2791/150/775/2786/54331/59345/776/51764/94235/55970/152/2793/2790 25 Epstein.Barr_virus R-HSA-948021 Transport to the Golgi and subsequent modification 127/5894 185/10654 1.2840769217373416e-4 3.026291840677453e-4 1.0958180906653853e-4 6811/23256/374/6711/11014/126003/10960/2153/2530/51807/10484/347688/5861/10381/1780/90411/8655/84516/832/3998/55738/7846/51226/9632/3630/81027/6709/79090/10652/54732/51164/58485/79861/10342/4253/2801/377/2517/22872/1315/8615/11316/8729/23423/10376/1314/10540/83696/27095/6399/7109/9334/378/6396/26286/1453/26958/140735/10959/84364/22820/84617/11258/6712/2890/1783/8703/10382/10802/93661/55860/830/7277/10671/9554/966/11196/1639/8702/10282/6710/8775/81876/4124/11015/347733/51143/51693/23243/5537/9871/10383/84790/10945/8704/1075/7280/829/1778/9919/10113/51399/55291/51014/122553/1781/6484/10121/2525/2804/57511/22870/64377/10972/381/4905/89866/2683/9276/287/4248/375/64689/288/10427/22818/372 127 Epstein.Barr_virus R-HSA-203927 MicroRNA (miRNA) biogenesis 22/5894 24/10654 1.334710886728043e-4 3.135122233099093e-4 1.1352254971907088e-4 5431/5435/5433/5439/192669/29102/5438/54487/57510/8575/26523/23405/5434/5436/5901/5432/27161/5440/5430/5441/192670/5437 22 Epstein.Barr_virus R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 22/5894 24/10654 1.334710886728043e-4 3.135122233099093e-4 1.1352254971907088e-4 5579/10811/5578/6280/1432/5879/5594/5880/5580/1535/5600/30849/4688/5590/653361/6279/5595/27035/5289/4689/5300/1536 22 Epstein.Barr_virus R-HSA-432720 Lysosome Vesicle Biogenesis 30/5894 35/10654 1.3523164228793514e-4 3.142723192227215e-4 1.1379777990034576e-4 8906/162/27243/1212/1174/1785/408/6456/3312/10053/9146/4074/6844/1213/1211/23431/8907/351/9179/9829/8905/8673/164/130340/2799/2647/81567/10717/6845/375 30 Epstein.Barr_virus R-HSA-111447 Activation of BAD and translocation to mitochondria 15/5894 15/10654 1.380385879741591e-4 3.142723192227215e-4 1.1379777990034576e-4 7531/10971/7533/2810/637/7534/10000/572/7532/208/7529/5533/596/207/5534 15 Epstein.Barr_virus R-HSA-2691230 Signaling by NOTCH1 HD Domain Mutants in Cancer 15/5894 15/10654 1.380385879741591e-4 3.142723192227215e-4 1.1379777990034576e-4 182/6868/57534/28514/7314/3714/102/6233/142678/9148/7311/4851/7316/54492/54567 15 Epstein.Barr_virus R-HSA-2691232 Constitutive Signaling by NOTCH1 HD Domain Mutants 15/5894 15/10654 1.380385879741591e-4 3.142723192227215e-4 1.1379777990034576e-4 182/6868/57534/28514/7314/3714/102/6233/142678/9148/7311/4851/7316/54492/54567 15 Epstein.Barr_virus R-HSA-354194 GRB2:SOS provides linkage to MAPK signaling for Integrins 15/5894 15/10654 1.380385879741591e-4 3.142723192227215e-4 1.1379777990034576e-4 5908/2244/3690/2885/7094/6714/2335/2266/2243/5747/3674/6654/7450/54518/5906 15 Epstein.Barr_virus R-HSA-372708 p130Cas linkage to MAPK signaling for integrins 15/5894 15/10654 1.380385879741591e-4 3.142723192227215e-4 1.1379777990034576e-4 5908/2244/3690/9564/7094/6714/2335/2266/2243/5747/3674/7450/54518/1398/5906 15 Epstein.Barr_virus R-HSA-430039 mRNA decay by 5' to 3' exoribonuclease 15/5894 15/10654 1.380385879741591e-4 3.142723192227215e-4 1.1379777990034576e-4 80153/219988/51690/11157/23644/27258/57819/23658/167227/1656/27257/25804/55802/196513/54464 15 Epstein.Barr_virus R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 15/5894 15/10654 1.380385879741591e-4 3.142723192227215e-4 1.1379777990034576e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Epstein.Barr_virus R-HSA-5099900 WNT5A-dependent internalization of FZD4 15/5894 15/10654 1.380385879741591e-4 3.142723192227215e-4 1.1379777990034576e-4 5579/5578/1212/5582/163/161/1856/8322/7474/1213/1211/1175/1173/409/160 15 Epstein.Barr_virus R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 15/5894 15/10654 1.380385879741591e-4 3.142723192227215e-4 1.1379777990034576e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Epstein.Barr_virus R-HSA-5358508 Mismatch Repair 15/5894 15/10654 1.380385879741591e-4 3.142723192227215e-4 1.1379777990034576e-4 4436/9156/6117/10714/4437/6118/3978/5424/2956/4292/5425/5111/6119/57804/5395 15 Epstein.Barr_virus R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 15/5894 15/10654 1.380385879741591e-4 3.142723192227215e-4 1.1379777990034576e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Epstein.Barr_virus R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 15/5894 15/10654 1.380385879741591e-4 3.142723192227215e-4 1.1379777990034576e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Epstein.Barr_virus R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 15/5894 15/10654 1.380385879741591e-4 3.142723192227215e-4 1.1379777990034576e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Epstein.Barr_virus R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 15/5894 15/10654 1.380385879741591e-4 3.142723192227215e-4 1.1379777990034576e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Epstein.Barr_virus R-HSA-5637810 Constitutive Signaling by EGFRvIII 15/5894 15/10654 1.380385879741591e-4 3.142723192227215e-4 1.1379777990034576e-4 5295/4893/5335/2885/3845/3265/5290/6464/6654/1956/2549/11140/1950/867/3320 15 Epstein.Barr_virus R-HSA-5637812 Signaling by EGFRvIII in Cancer 15/5894 15/10654 1.380385879741591e-4 3.142723192227215e-4 1.1379777990034576e-4 5295/4893/5335/2885/3845/3265/5290/6464/6654/1956/2549/11140/1950/867/3320 15 Epstein.Barr_virus R-HSA-69183 Processive synthesis on the lagging strand 15/5894 15/10654 1.380385879741591e-4 3.142723192227215e-4 1.1379777990034576e-4 2237/1763/5422/6117/10714/5558/6118/3978/5557/23649/5424/5425/5111/6119/57804 15 Epstein.Barr_virus R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 15/5894 15/10654 1.380385879741591e-4 3.142723192227215e-4 1.1379777990034576e-4 6456/30011/2885/7314/8027/2060/9146/6455/6233/4233/7311/7316/867/10254/6457 15 Epstein.Barr_virus R-HSA-74752 Signaling by Insulin receptor 59/5894 78/10654 1.5638317293778715e-4 3.554622363868603e-4 1.2871261916824926e-4 5295/3643/4893/2250/5291/535/10312/9965/2264/3630/2885/8660/9846/2252/2253/3845/3265/54106/5290/3667/8823/537/9550/9114/5594/8074/57761/2260/2249/2248/2247/529/2246/2251/523/528/5781/30849/5170/6464/2322/527/2263/208/6654/2549/5595/8817/2254/152831/5289/26281/10818/2261/2255/27006/5296/51382/2887 59 Epstein.Barr_virus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 32/5894 38/10654 1.6187995935625882e-4 3.673630690552519e-4 1.3302190208561843e-4 51741/2064/5308/4609/1387/7913/7022/83741/8089/163732/3815/348/2099/3329/10765/7020/4869/4839/339488/79047/10370/7329/29028/1956/7528/4605/4435/7021/7422/1026/7341/2033 32 Epstein.Barr_virus R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 27/5894 31/10654 1.6918082745891194e-4 3.826968235284391e-4 1.38574243510092e-4 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/79023/23636/53371/9688/8480 27 Epstein.Barr_virus R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 27/5894 31/10654 1.6918082745891194e-4 3.826968235284391e-4 1.38574243510092e-4 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/79023/23636/53371/9688/8480 27 Epstein.Barr_virus R-HSA-72766 Translation 191/5894 291/10654 1.8293811391198976e-4 4.1315236962146003e-4 1.4960217476286733e-4 6158/6138/5464/6227/6206/1965/6234/27335/6191/6128/6132/1917/84545/6129/1915/6176/55176/8668/6224/6146/6154/8662/26986/6202/65003/55052/6169/6175/6218/6728/64960/6173/64968/6167/116832/51069/28977/6156/6143/1973/28973/51116/6139/64975/3921/8665/10667/84340/6208/6170/92935/6203/51504/6171/10952/29093/6147/8666/6222/64432/4528/8667/6727/7818/6184/79731/6183/2935/6134/6747/6731/55699/6155/55157/10240/6729/6231/6142/7458/8663/23521/23107/8894/65008/1981/85476/6185/6207/64978/1977/6726/6233/28957/219402/51386/6188/1978/64965/7284/200916/6122/1968/6230/6194/2107/6166/1938/1650/1983/6136/6125/1937/23395/10056/6232/6160/6748/29927/1933/6193/6210/6229/6205/54148/140801/23438/6235/6181/8893/1975/7311/6223/25873/8664/6730/23708/9045/6187/6168/6157/6137/1974/55037/6144/9349/4736/8891/29088/327/51121/6159/56945/6217/1936/6152/79590/51065/6141/10480/6123/28998/1967/23480/6164/63931/8661/64963/9669/6209/1964/11224/6165/6130/8890/6204/64969/51081/6228/7965/55173/6124/2193/3646/6189/6135/6201/6161/51649/54998/8892/6133 191 Epstein.Barr_virus R-HSA-1368108 BMAL1:CLOCK,NPAS2 activates circadian gene expression 24/5894 27/10654 2.0188711886977246e-4 4.537622623798241e-4 1.6430698761219078e-4 79718/28999/5469/1628/1387/6907/2155/10499/23054/9575/85441/96764/5054/10135/5465/6604/80205/406/8553/4862/6256/10498/8648/551 24 Epstein.Barr_virus R-HSA-354192 Integrin alphaIIb beta3 signaling 24/5894 27/10654 2.0188711886977246e-4 4.537622623798241e-4 1.6430698761219078e-4 5770/5908/11069/2244/3690/2885/9564/7094/6714/2335/1445/2266/2243/5170/6464/5747/3674/6850/6654/7450/207/54518/1398/5906 24 Epstein.Barr_virus R-HSA-9006921 Integrin signaling 24/5894 27/10654 2.0188711886977246e-4 4.537622623798241e-4 1.6430698761219078e-4 5770/5908/11069/2244/3690/2885/9564/7094/6714/2335/1445/2266/2243/5170/6464/5747/3674/6850/6654/7450/207/54518/1398/5906 24 Epstein.Barr_virus R-HSA-110320 Translesion Synthesis by POLH 18/5894 19/10654 2.1087708813817403e-4 4.702124611892407e-4 1.7026359272479143e-4 5982/25898/6117/55666/7314/6118/5985/5984/6233/5111/6119/83932/5429/7311/5983/7316/7415/5981 18 Epstein.Barr_virus R-HSA-202430 Translocation of ZAP-70 to Immunological synapse 18/5894 19/10654 2.1087708813817403e-4 4.702124611892407e-4 1.7026359272479143e-4 3115/3113/3117/26191/3127/3126/916/3932/3120/3123/3122/920/7535/3125/3119/919/915/917 18 Epstein.Barr_virus R-HSA-392851 Prostacyclin signalling through prostacyclin receptor 18/5894 19/10654 2.1087708813817403e-4 4.702124611892407e-4 1.7026359272479143e-4 2788/2782/2787/10681/2792/2785/2783/2784/2791/2786/54331/59345/51764/94235/55970/2778/2793/2790 18 Epstein.Barr_virus R-HSA-3928664 Ephrin signaling 18/5894 19/10654 2.1087708813817403e-4 4.702124611892407e-4 1.7026359272479143e-4 1947/2051/2050/2047/2534/1948/8440/5062/5879/6714/1949/10627/2049/5063/6386/2048/5058/28964 18 Epstein.Barr_virus R-HSA-6804760 Regulation of TP53 Activity through Methylation 18/5894 19/10654 2.1087708813817403e-4 4.702124611892407e-4 1.7026359272479143e-4 133383/11200/472/79813/4194/56950/7314/7157/6233/10419/26013/7311/7316/2033/91875/133746/10919/4193 18 Epstein.Barr_virus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 21/5894 23/10654 2.2254348256438612e-4 4.946582621928771e-4 1.79115399619461e-4 7321/8239/9612/4089/23327/4088/7314/6497/51592/7323/7050/6233/142/4087/7311/64750/54778/7316/9611/3065/6498 21 Epstein.Barr_virus R-HSA-389948 PD-1 signaling 21/5894 23/10654 2.2254348256438612e-4 4.946582621928771e-4 1.79115399619461e-4 5777/3115/3113/3117/3127/3126/29126/1445/916/3932/5781/3120/3123/80380/3122/920/3125/3119/919/915/917 21 Epstein.Barr_virus R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 93/5894 132/10654 2.415992051225991e-4 5.300848340606483e-4 1.9194333571642073e-4 83990/151987/5892/9156/1763/7486/5982/472/6613/80198/4683/165918/84126/8900/8924/2067/672/6117/7334/10714/348654/83695/7314/6118/25/5888/51588/51720/63967/5531/116028/890/197342/7517/9656/84464/5985/5984/6233/7158/6047/5884/5810/5424/80010/7516/54107/580/11073/5425/641/5111/6119/3364/10524/5427/144715/5889/5429/1111/7329/79728/51426/146956/7311/5983/56655/51750/1017/54962/5893/5883/10111/57804/675/51548/545/7336/2072/29086/7316/79008/5426/10635/7341/8914/23514/5932/9025/79184/7156/5890/5981 93 Epstein.Barr_virus R-HSA-1250347 SHC1 events in ERBB4 signaling 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 4893/145957/9542/2885/3845/3265/1839/2069/6464/3084/6654/10718/685/2066 14 Epstein.Barr_virus R-HSA-162594 Early Phase of HIV Life Cycle 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 2237/7852/3981/3836/7518/3978/11168/5478/920/2547/1234/3159/7520/8815 14 Epstein.Barr_virus R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 5861/2801/5594/983/8548/8615/9133/891/81876/5347/5595/5862/26003/64689 14 Epstein.Barr_virus R-HSA-169893 Prolonged ERK activation events 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 5605/1399/5594/4914/673/2889/7529/5595/5604/57498/10818/4803/1398/5906 14 Epstein.Barr_virus R-HSA-174411 Polymerase switching on the C-strand of the telomere 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 5982/5422/10714/5558/5557/5985/5984/23649/5424/5425/5111/5983/57804/5981 14 Epstein.Barr_virus R-HSA-174490 Membrane binding and targetting of GAG proteins 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 55048/51271/7314/137492/51160/79720/9397/89853/6233/7311/93343/7251/155382/7316 14 Epstein.Barr_virus R-HSA-174495 Synthesis And Processing Of GAG, GAGPOL Polyproteins 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 55048/51271/7314/137492/51160/79720/9397/89853/6233/7311/93343/7251/155382/7316 14 Epstein.Barr_virus R-HSA-198323 AKT phosphorylates targets in the cytosol 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 84335/7249/2932/10000/2931/23608/572/208/1147/842/207/1027/1026/4193 14 Epstein.Barr_virus R-HSA-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 107/5567/5573/5613/801/805/5568/5566/5577/5575/114/5576/1385/808 14 Epstein.Barr_virus R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Epstein.Barr_virus R-HSA-4839744 truncated APC mutants destabilize the destruction complex 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Epstein.Barr_virus R-HSA-4839748 AMER1 mutants destabilize the destruction complex 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Epstein.Barr_virus R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 4436/9156/6117/10714/6118/3978/5424/2956/4292/5425/5111/6119/57804/5395 14 Epstein.Barr_virus R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 4436/9156/6117/10714/4437/6118/3978/5424/4292/5425/5111/6119/57804/5395 14 Epstein.Barr_virus R-HSA-5467337 APC truncation mutants have impaired AXIN binding 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Epstein.Barr_virus R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Epstein.Barr_virus R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Epstein.Barr_virus R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 79370/7159/23368/332/64065/7157/1121/604/5875/8626/7161/10397/9540/5876 14 Epstein.Barr_virus R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 9134/57060/1869/8900/144455/898/890/7157/79733/1820/1017/25946/1027/1026 14 Epstein.Barr_virus R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 7159/51230/23368/5458/10000/7157/5457/54971/8626/208/7161/25946/207/10848 14 Epstein.Barr_virus R-HSA-69091 Polymerase switching 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 5982/5422/10714/5558/5557/5985/5984/23649/5424/5425/5111/5983/57804/5981 14 Epstein.Barr_virus R-HSA-69109 Leading Strand Synthesis 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 5982/5422/10714/5558/5557/5985/5984/23649/5424/5425/5111/5983/57804/5981 14 Epstein.Barr_virus R-HSA-69166 Removal of the Flap Intermediate 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 2237/1763/5422/6117/10714/5558/6118/5557/23649/5424/5425/5111/6119/57804 14 Epstein.Barr_virus R-HSA-877312 Regulation of IFNG signaling 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 5777/5770/9021/3459/3717/3458/5781/8554/6772/8651/5771/3716/3460/7341 14 Epstein.Barr_virus R-HSA-8941856 RUNX3 regulates NOTCH signaling 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 182/22938/1387/9794/2648/55534/3280/84441/8850/864/10046/4851/2033/3516 14 Epstein.Barr_virus R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 79718/9612/6907/4204/814/801/805/5566/25942/8841/9611/2874/3065/808 14 Epstein.Barr_virus R-HSA-9005895 Pervasive developmental disorders 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 79718/9612/6907/4204/814/801/805/5566/25942/8841/9611/2874/3065/808 14 Epstein.Barr_virus R-HSA-9027284 Erythropoietin activates RAS 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 4893/3717/2885/2056/8660/3845/3265/1399/2057/7409/6464/2889/4067/6654 14 Epstein.Barr_virus R-HSA-918233 TRAF3-dependent IRF activation pathway 14/5894 14/10654 2.4978411157228843e-4 5.300848340606483e-4 1.9194333571642073e-4 80143/1387/64135/7187/29110/23586/3661/84282/3665/7706/9641/3456/57506/2033 14 Epstein.Barr_virus R-HSA-114608 Platelet degranulation 91/5894 129/10654 2.617007649205839e-4 5.545376148241891e-4 2.007976699771126e-4 2153/7042/5175/3959/3082/29106/3920/374354/2244/3309/3690/2162/87/10487/7040/5874/350/7043/967/5054/5099/1072/5340/7094/7414/83706/7123/12/3671/7273/22927/1191/9749/3273/27154/226/2335/5478/94121/22915/2266/7076/2243/801/805/928/351/135228/2316/3674/7277/334/10447/335/308/6403/197/81/9948/3481/5473/8407/7450/29789/10916/5005/7422/5004/5196/3827/1950/2621/5216/5768/710/6647/1893/7078/55664/2/948/88/5341/3479/5155/51368/808/213/5660/7057/5627 91 Epstein.Barr_virus R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 26/5894 30/10654 2.68655618552131e-4 5.684187297787192e-4 2.0582401168061954e-4 4893/817/1739/6196/6197/3845/3265/5923/818/57554/5594/2902/6195/801/4747/805/5170/2904/27330/816/5595/815/1742/88/1385/808 26 Epstein.Barr_virus R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 17/5894 18/10654 3.6278151482083685e-4 7.618411811237575e-4 2.758621416705185e-4 5295/11052/613/6776/11064/2885/9846/7750/8805/26127/5290/399687/6777/1523/9208/6774/6772 17 Epstein.Barr_virus R-HSA-5654221 Phospholipase C-mediated cascade; FGFR2 17/5894 18/10654 3.6278151482083685e-4 7.618411811237575e-4 2.758621416705185e-4 2250/5335/2252/2253/8823/8074/2249/2248/2247/2246/2251/2263/8817/2254/26281/2255/27006 17 Epstein.Barr_virus R-HSA-5654704 SHC-mediated cascade:FGFR3 17/5894 18/10654 3.6278151482083685e-4 7.618411811237575e-4 2.758621416705185e-4 4893/2250/2885/2253/3845/3265/8823/8074/2249/2247/2246/6464/6654/8817/2254/26281/2261 17 Epstein.Barr_virus R-HSA-5654710 PI-3K cascade:FGFR3 17/5894 18/10654 3.6278151482083685e-4 7.618411811237575e-4 2.758621416705185e-4 5295/2250/2885/2253/5290/8823/8074/2249/2247/2246/5781/2549/8817/2254/26281/10818/2261 17 Epstein.Barr_virus R-HSA-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 17/5894 18/10654 3.6278151482083685e-4 7.618411811237575e-4 2.758621416705185e-4 8792/10673/8740/7187/51330/958/9020/8742/959/4055/8600/330/115650/4050/7186/329/4049 17 Epstein.Barr_virus R-HSA-389357 CD28 dependent PI3K/Akt signaling 20/5894 22/10654 3.6973228072199557e-4 7.729766998155242e-4 2.7989430494947343e-4 5295/941/2534/2475/1326/5290/57761/9020/10000/3932/940/253260/5170/64223/8503/208/79109/207/942/5296 20 Epstein.Barr_virus R-HSA-5654712 FRS-mediated FGFR4 signaling 20/5894 22/10654 3.6973228072199557e-4 7.729766998155242e-4 2.7989430494947343e-4 4893/9965/2264/2885/2253/3845/3265/8823/8074/2249/2247/2246/2251/5781/6654/8817/2254/152831/26281/10818 20 Epstein.Barr_virus R-HSA-9613829 Chaperone Mediated Autophagy 20/5894 22/10654 3.6973228072199557e-4 7.729766998155242e-4 2.7989430494947343e-4 2670/1915/5116/3043/3920/3312/11315/7314/10013/123/6233/1068/3326/7311/1080/6035/7316/10226/3320/7431 20 Epstein.Barr_virus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 13/5894 13/10654 4.519559141711809e-4 9.283240456041628e-4 3.361454667058802e-4 2064/9542/7314/2065/9101/10000/6233/10193/3084/208/7311/207/7316 13 Epstein.Barr_virus R-HSA-202670 ERKs are inactivated 13/5894 13/10654 4.519559141711809e-4 9.283240456041628e-4 3.361454667058802e-4 1848/5518/51231/5515/1849/5594/5528/5519/5598/1846/5595/5516/1845 13 Epstein.Barr_virus R-HSA-209543 p75NTR recruits signalling complexes 13/5894 13/10654 4.519559141711809e-4 9.283240456041628e-4 3.361454667058802e-4 8878/3654/3551/7314/8767/6233/7189/7311/4804/5584/4615/7316/4803 13 Epstein.Barr_virus R-HSA-209560 NF-kB is activated and signals survival 13/5894 13/10654 4.519559141711809e-4 9.283240456041628e-4 3.361454667058802e-4 4790/8878/4792/3654/3551/7314/5970/6233/7189/7311/4804/7316/4803 13 Epstein.Barr_virus R-HSA-2892247 POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation 13/5894 13/10654 4.519559141711809e-4 9.283240456041628e-4 3.361454667058802e-4 6299/6657/55211/27022/5460/2041/2247/2649/6774/79923/7547/6997/57167 13 Epstein.Barr_virus R-HSA-2995383 Initiation of Nuclear Envelope Reformation 13/5894 13/10654 4.519559141711809e-4 9.283240456041628e-4 3.361454667058802e-4 5520/4001/5518/5515/221496/7444/2010/7112/4000/7443/23141/8815/23592 13 Epstein.Barr_virus R-HSA-2995410 Nuclear Envelope Reassembly 13/5894 13/10654 4.519559141711809e-4 9.283240456041628e-4 3.361454667058802e-4 5520/4001/5518/5515/221496/7444/2010/7112/4000/7443/23141/8815/23592 13 Epstein.Barr_virus R-HSA-5140745 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 13/5894 13/10654 4.519559141711809e-4 9.283240456041628e-4 3.361454667058802e-4 1212/163/4920/2535/161/7474/1213/1211/7855/1175/1173/160/4919 13 Epstein.Barr_virus R-HSA-5357786 TNFR1-induced proapoptotic signaling 13/5894 13/10654 4.519559141711809e-4 9.283240456041628e-4 3.361454667058802e-4 7124/7375/1540/8737/841/7128/8772/8717/27005/7186/56957/7132/9099 13 Epstein.Barr_virus R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13/5894 13/10654 4.519559141711809e-4 9.283240456041628e-4 3.361454667058802e-4 7531/10971/7533/2810/11200/7465/7534/983/7532/891/1111/7529/995 13 Epstein.Barr_virus R-HSA-879415 Advanced glycosylation endproduct receptor signaling 13/5894 13/10654 4.519559141711809e-4 9.283240456041628e-4 3.361454667058802e-4 177/6283/5594/351/1650/830/3958/829/5595/5589/3146/6288/6285 13 Epstein.Barr_virus R-HSA-8847993 ERBB2 Activates PTK6 Signaling 13/5894 13/10654 4.519559141711809e-4 9.283240456041628e-4 3.361454667058802e-4 2064/5753/145957/9542/1839/2065/2069/3084/10718/1956/685/1950/2066 13 Epstein.Barr_virus R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 34/5894 42/10654 4.5463851300446713e-4 9.324728685091621e-4 3.376477524845206e-4 2788/11069/9495/2782/8826/2787/5567/10681/112/5573/111/2792/2785/2783/2784/2791/5568/5566/2641/2786/5577/54331/5575/59345/51764/94235/114/3790/55970/2778/2793/5576/5906/2790 34 Epstein.Barr_virus R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 38/5894 48/10654 4.920470113789734e-4 0.001007729468719382 3.6489811308882726e-4 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/8812/905/2071/5432/22916/6917/5440/902/5430/6749/5441/4686/5437/2968/1022/8178 38 Epstein.Barr_virus R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 22/5894 25/10654 5.271660420690488e-4 0.0010749603205668864 3.8924235600521677e-4 51807/10381/10576/7846/81027/10574/10693/79861/10575/10376/84617/10382/7277/347733/10383/84790/22948/7280/10694/7203/908/6950 22 Epstein.Barr_virus R-HSA-937041 IKK complex recruitment mediated by RIP1 22/5894 25/10654 5.271660420690488e-4 0.0010749603205668864 3.8924235600521677e-4 7321/929/7334/3551/7314/23098/11035/8737/8517/7323/6233/330/7189/7311/23643/1147/7099/7316/7335/7322/329/148022 22 Epstein.Barr_virus R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 22/5894 25/10654 5.271660420690488e-4 0.0010749603205668864 3.8924235600521677e-4 3107/10484/811/567/3106/3309/9632/3133/6892/22872/10134/6396/3135/10802/6890/821/2923/9871/3105/6891/3134/10427 22 Epstein.Barr_virus R-HSA-70171 Glycolysis 53/5894 71/10654 5.887579606898868e-4 0.0011988168606232572 4.340907197408869e-4 23165/7167/5313/5211/348995/57122/3099/283209/23511/23279/23225/9972/5518/8021/2026/55746/5515/2597/5567/10762/5528/79902/26330/5519/9883/226/2821/6396/129401/230/4928/5903/55706/7175/5568/229/4927/5566/2023/669/8086/5516/81929/9631/5315/79023/23636/5214/53371/5230/9688/5213/8480 53 Epstein.Barr_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 19/5894 21/10654 6.118848999888001e-4 0.0012405216920522216 4.491920090923392e-4 9252/4893/4790/1387/2534/5894/3845/3265/5062/5567/5970/5568/5566/4067/5063/30835/5971/5058/2033 19 Epstein.Barr_virus R-HSA-5654688 SHC-mediated cascade:FGFR1 19/5894 21/10654 6.118848999888001e-4 0.0012405216920522216 4.491920090923392e-4 4893/2250/2885/2253/3845/3265/8074/2260/2249/2248/2247/2246/2251/6464/6654/2254/26281/2255/27006 19 Epstein.Barr_virus R-HSA-5654689 PI-3K cascade:FGFR1 19/5894 21/10654 6.118848999888001e-4 0.0012405216920522216 4.491920090923392e-4 5295/2250/2885/2253/5290/8074/2260/2249/2248/2247/2246/2251/5781/2549/2254/26281/10818/2255/27006 19 Epstein.Barr_virus R-HSA-196299 Beta-catenin phosphorylation cascade 16/5894 17/10654 6.223760783283212e-4 0.001256360318806238 4.549271644052064e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/23401/5529/5516/1499/5525/139285/5527 16 Epstein.Barr_virus R-HSA-2033519 Activated point mutants of FGFR2 16/5894 17/10654 6.223760783283212e-4 0.001256360318806238 4.549271644052064e-4 2250/2252/2253/8823/8074/2249/2248/2247/2246/2251/2263/8817/2254/26281/2255/27006 16 Epstein.Barr_virus R-HSA-9034015 Signaling by NTRK3 (TRKC) 16/5894 17/10654 6.223760783283212e-4 0.001256360318806238 4.549271644052064e-4 5295/4893/5335/2885/3845/3265/5290/3667/6714/25920/4908/6464/5802/6654/4916/581 16 Epstein.Barr_virus R-HSA-373755 Semaphorin interactions 49/5894 65/10654 6.416616199728346e-4 0.0012915849775418861 4.676819879027964e-4 5361/7305/388/2064/5788/8829/3688/54209/23365/79784/2534/9475/1808/2242/4628/6093/5362/5062/5879/23396/1072/7094/389/10371/3672/9855/2932/55558/23129/10627/4233/5063/3326/387/5058/1020/4629/3984/4627/3985/1809/971/10398/4637/3320/91584/103910/8851/6237 49 Epstein.Barr_virus R-HSA-8873719 RAB geranylgeranylation 49/5894 65/10654 6.416616199728346e-4 0.0012915849775418861 4.676819879027964e-4 5869/116442/1122/10981/5861/23011/51762/51552/9230/201475/5874/8073/5868/51209/326624/5872/9545/57111/5870/1121/23682/4218/401258/142684/7879/5875/9363/5864/53917/57403/81876/5867/54734/83871/53916/22931/10890/84932/5862/8766/9367/5876/51560/11021/5873/5878/11031/5865/338382 49 Epstein.Barr_virus R-HSA-182971 EGFR downregulation 26/5894 31/10654 7.859245322368683e-4 0.0015797083097961052 5.720112385002168e-4 374/6456/30011/2885/10252/7314/1839/8027/2060/2069/9146/6455/6233/29924/5782/998/7311/1956/10253/685/58513/7316/1950/867/10254/6457 26 Epstein.Barr_virus R-HSA-111932 CaMK IV-mediated phosphorylation of CREB 12/5894 12/10654 8.177005845987263e-4 0.0016046090969740695 5.810277955601315e-4 817/814/818/801/805/3838/10645/84254/816/815/1385/808 12 Epstein.Barr_virus R-HSA-170968 Frs2-mediated activation 12/5894 12/10654 8.177005845987263e-4 0.0016046090969740695 5.810277955601315e-4 5605/1399/5594/4914/673/2889/7529/5595/5604/10818/4803/5906 12 Epstein.Barr_virus R-HSA-176974 Unwinding of DNA 12/5894 12/10654 8.177005845987263e-4 0.0016046090969740695 5.810277955601315e-4 4174/84515/84296/64785/4175/4172/8318/4173/51659/4176/9837/4171 12 Epstein.Barr_virus R-HSA-2029481 FCGR activation 12/5894 12/10654 8.177005845987263e-4 0.0016046090969740695 5.810277955601315e-4 2268/2534/6714/7525/2214/2209/6850/4067/919/3055/917/2212 12 Epstein.Barr_virus R-HSA-210990 PECAM1 interactions 12/5894 12/10654 8.177005845987263e-4 0.0016046090969740695 5.810277955601315e-4 5777/5335/5175/2534/3690/3635/6714/7525/3685/3932/5781/4067 12 Epstein.Barr_virus R-HSA-2197563 NOTCH2 intracellular domain regulates transcription 12/5894 12/10654 8.177005845987263e-4 0.0016046090969740695 5.810277955601315e-4 4853/9794/388585/55534/3280/84441/3002/10046/2208/2033/1385/3516 12 Epstein.Barr_virus R-HSA-389359 CD28 dependent Vav1 pathway 12/5894 12/10654 8.177005845987263e-4 0.0016046090969740695 5.810277955601315e-4 941/2534/2885/5062/5879/7409/3932/940/5063/998/5058/942 12 Epstein.Barr_virus R-HSA-417957 P2Y receptors 12/5894 12/10654 8.177005845987263e-4 0.0016046090969740695 5.810277955601315e-4 10161/64805/2840/5028/5029/53829/27334/9934/5032/5031/5030/2846 12 Epstein.Barr_virus R-HSA-430116 GP1b-IX-V activation signalling 12/5894 12/10654 8.177005845987263e-4 0.0016046090969740695 5.810277955601315e-4 5295/5894/7534/6714/2814/2316/1277/7450/2812/2811/2815/1278 12 Epstein.Barr_virus R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 12/5894 12/10654 8.177005845987263e-4 0.0016046090969740695 5.810277955601315e-4 834/55367/472/8738/7157/839/317/843/8626/7161/835/58484 12 Epstein.Barr_virus R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 12/5894 12/10654 8.177005845987263e-4 0.0016046090969740695 5.810277955601315e-4 7159/23368/8797/7157/8626/7161/8795/8793/3486/355/8794/124446 12 Epstein.Barr_virus R-HSA-8866907 Activation of the TFAP2 (AP-2) family of transcription factors 12/5894 12/10654 8.177005845987263e-4 0.0016046090969740695 5.810277955601315e-4 51741/1387/7022/83741/8089/163732/7020/339488/10370/4435/7021/2033 12 Epstein.Barr_virus R-HSA-8984722 Interleukin-35 Signalling 12/5894 12/10654 8.177005845987263e-4 0.0016046090969740695 5.810277955601315e-4 3717/3572/10148/3592/7297/6775/3595/821/6774/6772/3716/9466 12 Epstein.Barr_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 12/5894 12/10654 8.177005845987263e-4 0.0016046090969740695 5.810277955601315e-4 7187/7314/29110/3661/6233/10010/3665/7098/7311/9641/7316/148022 12 Epstein.Barr_virus R-HSA-9020558 Interleukin-2 signaling 12/5894 12/10654 8.177005845987263e-4 0.0016046090969740695 5.810277955601315e-4 6776/3558/3718/3932/6777/6464/6850/3716/2185/3561/3560/3559 12 Epstein.Barr_virus R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 12/5894 12/10654 8.177005845987263e-4 0.0016046090969740695 5.810277955601315e-4 5295/5291/3717/2056/8660/5290/5294/2057/4067/5293/2549/23533 12 Epstein.Barr_virus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12/5894 12/10654 8.177005845987263e-4 0.0016046090969740695 5.810277955601315e-4 64135/3551/8737/841/8517/23586/84282/8772/7706/843/1147/57506 12 Epstein.Barr_virus R-HSA-8940973 RUNX2 regulates osteoblast differentiation 21/5894 24/10654 8.460502398054573e-4 0.0016556226528599144 5.99499767316948e-4 5925/10413/25/5594/3280/10013/2737/865/6714/7525/1277/23493/367/860/5595/8841/23462/4094/23314/25925/25937 21 Epstein.Barr_virus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 21/5894 24/10654 8.460502398054573e-4 0.0016556226528599144 5.99499767316948e-4 374/1839/5594/2069/10000/595/7514/2353/5747/208/1956/5595/596/685/2309/207/6722/1027/1950/2002/1385 21 Epstein.Barr_virus R-HSA-9006931 Signaling by Nuclear Receptors 192/5894 299/10654 9.599393108041339e-4 0.0018758814031964116 6.792553017970772e-4 5295/2788/374/3725/4893/857/7764/79718/7031/5160/2770/10901/27327/10274/5915/5431/5435/5433/1509/5469/1105/9612/4609/1387/6907/8312/2782/5439/192669/10499/1386/5914/4343/3845/904/1071/7392/3265/8877/2773/10062/2787/6387/1839/5290/6801/4316/64241/5594/2069/10681/1737/5481/5438/348/4313/865/1655/6667/2792/6714/2099/2494/8850/5467/10000/2785/595/2783/2784/2771/7514/1025/2353/6257/26523/801/29116/2791/2957/805/5105/5170/2963/3838/5434/5590/6464/112724/1374/7090/5241/5747/5436/1903/3315/4318/200845/5885/19/57678/7033/2962/8503/10524/5346/2171/8243/4602/9682/2786/208/3326/23030/6908/1956/5536/3169/51109/858/5432/3480/10728/5595/7528/3727/10123/27161/2354/596/5440/8841/685/54331/4435/347/2309/9687/59345/8204/5430/207/5451/2625/57690/6722/1027/51764/94235/5441/10735/6720/192670/2100/1950/9611/55970/2874/2194/4314/346562/2289/7391/2958/5437/2793/3320/2033/221656/4846/9126/9166/3065/2002/2066/861/23028/6256/23112/7376/10498/1385/1738/5296/808/6258/3276/5916/8202/8648/2288/2790 192 Epstein.Barr_virus R-HSA-165159 mTOR signalling 32/5894 40/10654 9.916808873585436e-4 0.0019325415630380483 6.997719047696968e-4 5563/53632/6198/29904/2475/92335/51719/84335/51422/7249/1981/1977/1978/57521/28956/6194/389541/64223/5571/6794/6009/208/1975/55004/5562/5564/5565/7248/7529/207/8649/10542 32 Epstein.Barr_virus R-HSA-6783310 Fanconi Anemia Pathway 32/5894 40/10654 9.916808873585436e-4 0.0019325415630380483 6.997719047696968e-4 80198/84126/57599/2067/6117/7314/22909/6118/2176/197342/84464/2177/29089/6233/2188/57697/6119/55215/146956/7311/2175/2178/545/2072/7316/79008/9937/7398/64858/2189/55120/2187 32 Epstein.Barr_virus R-HSA-5628897 TP53 Regulates Metabolic Genes 62/5894 86/10654 9.974006788836915e-4 0.0019409996613960635 7.028345760787751e-4 5563/7531/10971/9997/27327/7295/7533/2810/53632/7001/192669/2475/4513/4343/7296/9377/1329/2936/51422/7249/27244/7534/2821/10000/2877/54541/7157/50484/26523/2744/57521/28956/83667/389541/7532/64223/5571/10128/25824/6009/8626/208/55004/5562/4697/5564/5565/7248/7529/27161/27165/207/57690/192670/2539/54205/143686/8649/5728/23112/10542/5052 62 Epstein.Barr_virus R-HSA-164938 Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 18/5894 20/10654 0.001008343190473208 0.0019568811986149016 7.085852692399749e-4 162/1174/567/163/161/10053/926/3932/1175/8907/940/1173/160/920/8905/164/130340/375 18 Epstein.Barr_virus R-HSA-5654706 FRS-mediated FGFR3 signaling 18/5894 20/10654 0.001008343190473208 0.0019568811986149016 7.085852692399749e-4 4893/2250/2885/2253/3845/3265/8823/8074/2249/2247/2246/5781/6654/8817/2254/26281/10818/2261 18 Epstein.Barr_virus R-HSA-445717 Aquaporin-mediated transport 40/5894 52/10654 0.0010101733565276098 0.001957732662030781 7.088935835281472e-4 2788/358/107/2782/2787/22841/5567/10681/112/5573/111/2792/2785/2783/2784/196883/115/2791/5568/359/113/5566/2786/5577/109/54331/5575/59345/51764/94235/114/108/8766/55970/2778/2793/5576/4645/551/2790 40 Epstein.Barr_virus R-HSA-167169 HIV Transcription Elongation 36/5894 46/10654 0.0010279076362462137 0.0019839040386809637 7.183702201186449e-4 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/4686/5437/2968/1022/8178 36 Epstein.Barr_virus R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 36/5894 46/10654 0.0010279076362462137 0.0019839040386809637 7.183702201186449e-4 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/4686/5437/2968/1022/8178 36 Epstein.Barr_virus R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 36/5894 46/10654 0.0010279076362462137 0.0019839040386809637 7.183702201186449e-4 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/4686/5437/2968/1022/8178 36 Epstein.Barr_virus R-HSA-3000170 Syndecan interactions 23/5894 27/10654 0.0010460022902506513 0.002013303997787505 7.290159240857013e-4 6385/5578/1289/7448/3688/3693/3690/87/6382/7040/3655/2247/2335/3685/9672/3691/8573/1277/51399/6383/3673/7057/1278 23 Epstein.Barr_virus R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 23/5894 27/10654 0.0010460022902506513 0.002013303997787505 7.290159240857013e-4 356/836/929/26060/1612/8737/841/8797/1613/8772/8717/8743/8837/8795/23643/7186/842/355/7099/9500/23604/1630/148022 23 Epstein.Barr_virus R-HSA-1433559 Regulation of KIT signaling 15/5894 16/10654 0.0010644372327109739 0.0020404130605236243 7.388320961309498e-4 5777/5578/2534/2885/10603/3815/9306/6714/7525/3932/8651/4067/6654/867/4254 15 Epstein.Barr_virus R-HSA-418038 Nucleotide-like (purinergic) receptors 15/5894 16/10654 0.0010644372327109739 0.0020404130605236243 7.388320961309498e-4 10161/64805/2840/5028/5029/53829/27334/134/9934/135/5032/140/5031/5030/2846 15 Epstein.Barr_virus R-HSA-429958 mRNA decay by 3' to 5' exoribonuclease 15/5894 16/10654 0.0010644372327109739 0.0020404130605236243 7.388320961309498e-4 5393/23404/28960/10767/11340/80349/23016/118460/9652/51010/56915/22894/51013/6499/54512 15 Epstein.Barr_virus R-HSA-3928663 EPHA-mediated growth cone collapse 25/5894 30/10654 0.0012050101830412521 0.0023035996298084805 8.341317628603633e-4 2042/2045/285220/79784/2534/9475/4628/6093/2041/6714/2043/7525/1942/25791/10627/4067/2044/387/4629/4627/10398/4637/1946/103910/1969 25 Epstein.Barr_virus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 25/5894 30/10654 0.0012050101830412521 0.0023035996298084805 8.341317628603633e-4 11065/7321/65264/8239/3093/7347/7328/7332/7314/90268/10477/29089/7324/6233/7874/7317/8078/7311/997/7319/7320/7316/7322/55284/27338 25 Epstein.Barr_virus R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 20/5894 23/10654 0.00135099093510607 0.002575669709612792 9.326481423353843e-4 5431/5435/5433/5439/51497/5438/7936/6829/25920/2963/5434/5436/2962/5432/22916/5440/5430/5441/4686/5437 20 Epstein.Barr_virus R-HSA-5654693 FRS-mediated FGFR1 signaling 20/5894 23/10654 0.00135099093510607 0.002575669709612792 9.326481423353843e-4 4893/2250/2885/2253/3845/3265/8074/2260/2249/2248/2247/2246/2251/5781/6654/2254/26281/10818/2255/27006 20 Epstein.Barr_virus R-HSA-4551638 SUMOylation of chromatin organization proteins 52/5894 71/10654 0.001398388018685907 0.0026624248204209352 9.640621053258015e-4 1912/23165/6045/80012/348995/6613/57122/23511/9759/1911/23279/23225/23512/57332/1107/9972/6612/8021/55746/83746/10762/79902/9883/84733/3066/9063/6396/129401/7703/6015/8554/4928/5903/55706/7175/8535/4927/8086/7329/648/23468/81929/9631/79023/23636/53371/9688/7341/3065/23314/6304/8480 52 Epstein.Barr_virus R-HSA-1059683 Interleukin-6 signaling 11/5894 11/10654 0.001479311120497069 0.002738672034920232 9.916711666490045e-4 9021/3717/3569/3572/3570/7297/5781/6774/6772/3716/867 11 Epstein.Barr_virus R-HSA-1236977 Endosomal/Vacuolar pathway 11/5894 11/10654 0.001479311120497069 0.002738672034920232 9.916711666490045e-4 3107/567/3106/3133/1515/1514/3135/4012/3105/1520/3134 11 Epstein.Barr_virus R-HSA-174414 Processive synthesis on the C-strand of the telomere 11/5894 11/10654 0.001479311120497069 0.002738672034920232 9.916711666490045e-4 2237/1763/6117/10714/6118/3978/5424/5425/5111/6119/57804 11 Epstein.Barr_virus R-HSA-193692 Regulated proteolysis of p75NTR 11/5894 11/10654 0.001479311120497069 0.002738672034920232 9.916711666490045e-4 4790/23385/6868/5970/5664/5663/7189/83464/55851/51107/4804 11 Epstein.Barr_virus R-HSA-2025928 Calcineurin activates NFAT 11/5894 11/10654 0.001479311120497069 0.002738672034920232 9.916711666490045e-4 5530/4773/2280/5478/801/805/4772/4775/5532/5534/808 11 Epstein.Barr_virus R-HSA-2514853 Condensation of Prometaphase Chromosomes 11/5894 11/10654 0.001479311120497069 0.002738672034920232 9.916711666490045e-4 1459/1460/1457/64151/10051/983/23397/9133/891/10592/9918 11 Epstein.Barr_virus R-HSA-3371378 Regulation by c-FLIP 11/5894 11/10654 0.001479311120497069 0.002738672034920232 9.916711666490045e-4 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355 11 Epstein.Barr_virus R-HSA-400451 Free fatty acids regulate insulin secretion 11/5894 11/10654 0.001479311120497069 0.002738672034920232 9.916711666490045e-4 5331/2769/2776/2181/2182/2864/23236/5330/2767/948/9630 11 Epstein.Barr_virus R-HSA-4755510 SUMOylation of immune response proteins 11/5894 11/10654 0.001479311120497069 0.002738672034920232 9.916711666490045e-4 4792/6612/51588/8517/5970/4791/10210/7329/9641/7341/10401 11 Epstein.Barr_virus R-HSA-5218900 CASP8 activity is inhibited 11/5894 11/10654 0.001479311120497069 0.002738672034920232 9.916711666490045e-4 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355 11 Epstein.Barr_virus R-HSA-5603041 IRAK4 deficiency (TLR2/4) 11/5894 11/10654 0.001479311120497069 0.002738672034920232 9.916711666490045e-4 10333/929/51135/7096/695/23643/7099/4615/114609/948/7097 11 Epstein.Barr_virus R-HSA-5625970 RHO GTPases activate KTN1 11/5894 11/10654 0.001479311120497069 0.002738672034920232 9.916711666490045e-4 64837/3798/5879/89953/147700/3831/3895/998/387/391/3799 11 Epstein.Barr_virus R-HSA-5655291 Signaling by FGFR4 in disease 11/5894 11/10654 0.001479311120497069 0.002738672034920232 9.916711666490045e-4 5295/4893/5335/2264/2885/3845/3265/5290/6654/2549/10818 11 Epstein.Barr_virus R-HSA-68689 CDC6 association with the ORC:origin complex 11/5894 11/10654 0.001479311120497069 0.002738672034920232 9.916711666490045e-4 1869/84515/4998/990/5001/23594/4999/5000/1870/23595/1871 11 Epstein.Barr_virus R-HSA-69416 Dimerization of procaspase-8 11/5894 11/10654 0.001479311120497069 0.002738672034920232 9.916711666490045e-4 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355 11 Epstein.Barr_virus R-HSA-8875555 MET activates RAP1 and RAC1 11/5894 11/10654 0.001479311120497069 0.002738672034920232 9.916711666490045e-4 5908/3082/2885/1399/5879/85440/4233/2889/2549/1398/5906 11 Epstein.Barr_virus R-HSA-8934903 Receptor Mediated Mitophagy 11/5894 11/10654 0.001479311120497069 0.002738672034920232 9.916711666490045e-4 1459/9140/1460/9474/1457/84557/139341/192111/6714/8408/81631 11 Epstein.Barr_virus R-HSA-9013700 NOTCH4 Activation and Transmission of Signal to the Nucleus 11/5894 11/10654 0.001479311120497069 0.002738672034920232 9.916711666490045e-4 182/23385/7534/102/5664/5663/4855/83464/55851/51107/54567 11 Epstein.Barr_virus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 11/5894 11/10654 0.001479311120497069 0.002738672034920232 9.916711666490045e-4 7314/257397/23118/10454/6233/7098/7189/7311/6885/7316/148022 11 Epstein.Barr_virus R-HSA-9614399 Regulation of localization of FOXO transcription factors 11/5894 11/10654 0.001479311120497069 0.002738672034920232 9.916711666490045e-4 2308/10971/2810/7534/10000/7532/4303/208/7529/2309/207 11 Epstein.Barr_virus R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 11/5894 11/10654 0.001479311120497069 0.002738672034920232 9.916711666490045e-4 7314/257397/23118/80216/10454/6233/92610/7189/7311/6885/7316 11 Epstein.Barr_virus R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 17/5894 19/10654 0.0016539691416234696 0.003057995508888596 0.0011072979660360456 1869/4609/5928/990/7027/7153/5934/993/7029/286826/5111/1874/55957/4149/1875/5933/3065 17 Epstein.Barr_virus R-HSA-1170546 Prolactin receptor signaling 14/5894 15/10654 0.0018142214419460973 0.0033280437663861266 0.001205082245113444 8454/6776/9978/3717/5618/8945/2690/5617/6777/5781/1442/2689/6500/2688 14 Epstein.Barr_virus R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 14/5894 15/10654 0.0018142214419460973 0.0033280437663861266 0.001205082245113444 22954/7314/29110/81844/51428/3661/6233/23220/7311/81030/6737/147945/7316/11277 14 Epstein.Barr_virus R-HSA-5654228 Phospholipase C-mediated cascade; FGFR4 14/5894 15/10654 0.0018142214419460973 0.0033280437663861266 0.001205082245113444 5335/9965/2264/2253/8823/8074/2249/2247/2246/2251/8817/2254/152831/26281 14 Epstein.Barr_virus R-HSA-6785631 ERBB2 Regulates Cell Motility 14/5894 15/10654 0.0018142214419460973 0.0033280437663861266 0.001205082245113444 2064/145957/9542/1839/2065/2069/1729/3084/10718/387/1956/685/1950/2066 14 Epstein.Barr_virus R-HSA-75892 Platelet Adhesion to exposed collagen 14/5894 15/10654 0.0018142214419460973 0.0033280437663861266 0.001205082245113444 3688/2534/51206/3672/2814/1277/4067/7450/2812/3673/2811/2815/1278/2207 14 Epstein.Barr_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 14/5894 15/10654 0.0018142214419460973 0.0033280437663861266 0.001205082245113444 3654/51135/7334/7314/54106/6233/51311/3665/7189/7311/51284/4615/7316/7335 14 Epstein.Barr_virus R-HSA-1660499 Synthesis of PIPs at the plasma membrane 40/5894 53/10654 0.0019252242756210912 0.003527071036196452 0.001277149875823202 5295/5291/5783/5286/55300/8871/660/51552/8396/54477/23396/3635/5290/5868/59339/81846/79837/55361/146850/5294/8394/8898/8776/22874/8867/66036/8503/3636/59338/5867/5293/57664/5305/64419/5287/23533/5728/5296/375/4952 40 Epstein.Barr_virus R-HSA-429947 Deadenylation of mRNA 21/5894 25/10654 0.0025201922779216 0.004611067015651093 0.0016696640373883432 26986/25904/1973/55571/57472/85456/29883/1981/1977/9924/5073/4850/255967/246175/4848/23019/1975/1974/4849/9337/9775 21 Epstein.Barr_virus R-HSA-110056 MAPK3 (ERK1) activation 10/5894 10/10654 0.0026760345966299766 0.004784219412272398 0.0017323623951968283 3717/3569/3572/983/3570/7297/5781/3716/5595/5604 10 Epstein.Barr_virus R-HSA-1250342 PI3K events in ERBB4 signaling 10/5894 10/10654 0.0026760345966299766 0.004784219412272398 0.0017323623951968283 5295/145957/9542/1839/5290/2069/3084/10718/685/2066 10 Epstein.Barr_virus R-HSA-174437 Removal of the Flap Intermediate from the C-strand 10/5894 10/10654 0.0026760345966299766 0.004784219412272398 0.0017323623951968283 2237/1763/6117/10714/6118/5424/5425/5111/6119/57804 10 Epstein.Barr_virus R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 10/5894 10/10654 0.0026760345966299766 0.004784219412272398 0.0017323623951968283 5563/53632/1432/51422/5600/6300/5571/5564/5565/10891 10 Epstein.Barr_virus R-HSA-2465910 MASTL Facilitates Mitotic Progression 10/5894 10/10654 0.0026760345966299766 0.004784219412272398 0.0017323623951968283 5518/55844/84930/5515/983/5519/2029/891/5516/10776 10 Epstein.Barr_virus R-HSA-381183 ATF6 (ATF6-alpha) activates chaperone genes 10/5894 10/10654 0.0026760345966299766 0.004784219412272398 0.0017323623951968283 811/3309/4801/468/7184/7494/4800/22926/4802/1649 10 Epstein.Barr_virus R-HSA-390450 Folding of actin by CCT/TriC 10/5894 10/10654 0.0026760345966299766 0.004784219412272398 0.0017323623951968283 10576/10574/10693/10575/60/22948/10694/7203/908/6950 10 Epstein.Barr_virus R-HSA-399997 Acetylcholine regulates insulin secretion 10/5894 10/10654 0.0026760345966299766 0.004784219412272398 0.0017323623951968283 5331/5578/2769/2776/1131/23236/4082/5330/2767/9630 10 Epstein.Barr_virus R-HSA-442729 CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde 10/5894 10/10654 0.0026760345966299766 0.004784219412272398 0.0017323623951968283 814/818/801/805/3838/10645/84254/816/1385/808 10 Epstein.Barr_virus R-HSA-450341 Activation of the AP-1 family of transcription factors 10/5894 10/10654 0.0026760345966299766 0.004784219412272398 0.0017323623951968283 3725/1432/1386/5601/5594/2353/5600/5602/5595/5599 10 Epstein.Barr_virus R-HSA-5602498 MyD88 deficiency (TLR2/4) 10/5894 10/10654 0.0026760345966299766 0.004784219412272398 0.0017323623951968283 10333/929/7096/695/23643/7099/4615/114609/948/7097 10 Epstein.Barr_virus R-HSA-74749 Signal attenuation 10/5894 10/10654 0.0026760345966299766 0.004784219412272398 0.0017323623951968283 3643/3630/2885/8660/3667/5594/6464/6654/5595/2887 10 Epstein.Barr_virus R-HSA-8853334 Signaling by FGFR3 fusions in cancer 10/5894 10/10654 0.0026760345966299766 0.004784219412272398 0.0017323623951968283 5295/4893/2885/3845/3265/5290/6654/2549/10818/2261 10 Epstein.Barr_virus R-HSA-8875656 MET receptor recycling 10/5894 10/10654 0.0026760345966299766 0.004784219412272398 0.0017323623951968283 3082/2885/1399/382/4233/5867/2549/53916/1398/23163 10 Epstein.Barr_virus R-HSA-8877330 RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) 10/5894 10/10654 0.0026760345966299766 0.004784219412272398 0.0017323623951968283 3558/4773/865/3458/1493/1378/50943/861/8784/3559 10 Epstein.Barr_virus R-HSA-9020958 Interleukin-21 signaling 10/5894 10/10654 0.0026760345966299766 0.004784219412272398 0.0017323623951968283 6776/50615/3718/6777/59067/6775/6774/6772/3716/3561 10 Epstein.Barr_virus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 10/5894 10/10654 0.0026760345966299766 0.004784219412272398 0.0017323623951968283 7314/257397/23118/10454/6233/3656/7189/7311/6885/7316 10 Epstein.Barr_virus R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 10/5894 10/10654 0.0026760345966299766 0.004784219412272398 0.0017323623951968283 2308/7295/1387/10628/23411/8850/4303/23410/2309/2033 10 Epstein.Barr_virus R-HSA-111471 Apoptotic factor-mediated response 16/5894 18/10654 0.0026991325863881823 0.004813282064699839 0.001742885960658902 55075/836/840/578/5594/22900/708/331/57099/317/1029/56616/5595/842/54205/581 16 Epstein.Barr_virus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 16/5894 18/10654 0.0026991325863881823 0.004813282064699839 0.001742885960658902 929/7187/7314/23098/29110/3661/6233/10010/5781/3665/7311/9641/23643/7099/7316/148022 16 Equine_arteritis_virus R-HSA-2682334 EPH-Ephrin signaling 36/341 92/10654 2.3135067464885668e-30 2.387538962376201e-27 1.5658787768338404e-27 10627/10097/6093/163/10092/4637/1173/1213/4067/103910/1072/387/1211/60/160/79784/71/5063/2534/9475/10095/5058/10093/10398/10109/998/5062/4627/4628/10552/4629/10094/1212/5879/7525/10096 36 Equine_arteritis_virus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 33/341 86/10654 1.4322643441927654e-27 7.39048401603467e-25 4.847084070083938e-25 10097/10092/4644/4650/2209/4067/1072/3710/60/5296/5581/917/3320/71/2534/10095/2214/2212/5058/10093/10109/998/4627/10552/3709/4620/10094/4641/5879/2885/7525/10096/3326 33 Equine_arteritis_virus R-HSA-5627123 RHO GTPases activate PAKs 20/341 24/10654 6.942991780357418e-27 2.3883891724429515e-24 1.566436391147305e-24 10627/2017/4637/103910/79784/5063/4638/5058/801/4659/10398/998/5062/4627/4628/2316/4660/4629/5500/5879 20 Equine_arteritis_virus R-HSA-5627117 RHO GTPases Activate ROCKs 18/341 20/10654 1.4312224247841349e-25 3.692553855943068e-23 2.421778997726839e-23 10627/6093/388/4637/103910/1072/387/79784/9475/5058/4659/10398/4627/4628/4660/4629/5500/389 18 Equine_arteritis_virus R-HSA-445355 Smooth Muscle Contraction 23/341 40/10654 1.0829557253076168e-24 2.235220617034921e-22 1.465980066047995e-22 10627/7168/4637/302/7169/103910/7171/59/4638/29895/93408/72/5058/801/800/10398/5062/4636/4629/493829/58498/7170/140465 23 Equine_arteritis_virus R-HSA-195258 RHO GTPase Effectors 54/341 327/10654 3.915113451557983e-24 6.733995136679731e-22 4.416522718161024e-22 10627/10097/6093/388/1080/10092/2017/8826/7277/4637/79980/6280/103910/1072/387/999/60/7534/54908/79784/71/5063/9475/55143/4638/10095/1499/5501/5058/801/4659/11113/10093/10398/10109/998/5289/5062/4627/4628/2316/10552/4660/10971/4629/10094/5500/389/5879/2885/4221/5515/1027/10096 54 Equine_arteritis_virus R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 26/341 61/10654 2.3444441548688103e-23 3.456380525463731e-21 2.2668835963618725e-21 10097/10092/4644/4650/2209/1072/60/917/3320/71/10095/2214/2212/5058/10093/10109/998/4627/10552/4620/10094/4641/5879/2885/10096/3326 26 Equine_arteritis_virus R-HSA-5625900 RHO GTPases activate CIT 17/341 20/10654 2.738157042393275e-23 3.532222584687325e-21 2.3166249713932577e-21 10627/388/4637/103910/387/79784/4659/11113/10398/4627/4628/4660/4629/5500/389/5879/1027 17 Equine_arteritis_virus R-HSA-194315 Signaling by Rho GTPases 59/341 455/10654 7.878010112300129e-21 9.033451595437481e-19 5.924632166326296e-19 10627/10097/6093/388/1080/10092/4650/2017/8826/7277/4637/79980/6280/103910/1072/387/999/60/5296/7534/54908/79784/71/5063/9475/55143/4638/10095/1499/57584/9828/5501/5058/9824/801/4659/11113/10093/10398/10109/998/5289/5062/4627/4628/2316/10552/4660/10971/4629/10094/5500/389/5879/2885/4221/5515/1027/10096 59 Equine_arteritis_virus R-HSA-8856828 Clathrin-mediated endocytosis 34/341 146/10654 2.3755028469587673e-20 2.4515189380614478e-18 1.6078403479941972e-18 8301/10097/409/163/1080/10092/29978/2017/1173/867/29763/1213/85439/1956/1211/60/160/917/338/71/408/10093/10109/115548/5286/10552/10094/2060/1212/3092/1601/2885/9026/10096 34 Equine_arteritis_virus R-HSA-3928662 EPHB-mediated forward signaling 20/341 42/10654 1.9855069752364258e-19 1.862766544039992e-17 1.2217042919397337e-17 10097/6093/10092/4067/1072/387/60/71/2534/9475/10095/5058/10093/10109/998/10552/10094/5879/7525/10096 20 Equine_arteritis_virus R-HSA-397014 Muscle contraction 38/341 209/10654 1.2032437743534276e-18 1.0347896459439477e-16 6.78671707815135e-17 10627/7168/4621/4634/4637/4632/4607/4624/302/7169/103910/3710/7171/4633/59/4626/4638/29895/7111/93408/29766/70/72/5058/801/800/10398/5062/4636/3709/4629/493829/58498/7170/140465/58/4635/7273 38 Equine_arteritis_virus R-HSA-373755 Semaphorin interactions 22/341 65/10654 2.3142490454475063e-17 1.8371577037706357e-15 1.2049086123261105e-15 10627/6093/388/4637/103910/1072/387/3320/79784/5063/2534/9475/7305/5058/10398/5062/4627/4628/4629/389/5879/3326 22 Equine_arteritis_virus R-HSA-390522 Striated Muscle Contraction 17/341 36/10654 1.2945129556129667e-16 9.542409787089868e-15 6.258434815482238e-15 7168/4621/4634/4632/4607/4624/7169/7171/4633/4626/7111/29766/70/7170/58/4635/7273 17 Equine_arteritis_virus R-HSA-400685 Sema4D in semaphorin signaling 14/341 25/10654 2.9492800961251614e-15 2.029104706134111e-13 1.3307979661813884e-13 10627/6093/388/4637/103910/387/79784/9475/10398/4627/4628/4629/389/5879 14 Equine_arteritis_virus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 21/341 72/10654 3.869458201824114e-15 2.495800540176553e-13 1.6368826472190165e-13 5898/4644/55763/7277/60/7534/71/54536/8766/60412/801/10640/4627/11336/207/10971/149371/4641/5879/55770/23265 21 Equine_arteritis_virus R-HSA-416572 Sema4D induced cell migration and growth-cone collapse 13/341 21/10654 4.7688853068088566e-015 2.894993903898082e-13 1.8986955122464983e-13 10627/6093/388/4637/103910/387/79784/9475/10398/4627/4628/4629/389 13 Equine_arteritis_virus R-HSA-3928663 EPHA-mediated growth cone collapse 14/341 30/10654 8.319703212840041e-14 4.769963175361624e-12 3.128403020968507e-12 10627/6093/4637/4067/103910/387/79784/2534/9475/10398/4627/4628/4629/7525 14 Equine_arteritis_virus R-HSA-76002 Platelet activation, signaling and aggregation 33/341 262/10654 1.2330609836006614e-11 6.69746807934675e-10 4.3925662739901677e-10 409/388/7277/4067/1072/387/3710/6464/5296/5581/7534/81/135228/3309/9948/2335/2534/408/2162/2783/55970/801/87/998/2770/2316/207/5478/3709/2771/5879/2885/7273 33 Equine_arteritis_virus R-HSA-4420097 VEGFA-VEGFR2 Pathway 20/341 99/10654 3.137649502169413e-11 1.619027143119417e-9 1.0618466473131223e-9 6093/387/3710/60/5296/3320/71/5063/3845/2534/9475/1499/3728/5058/801/998/5062/207/3709/5879 20 Equine_arteritis_virus R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 13/341 36/10654 3.5047024156698315e-11 1.7223109014148888e-9 1.1295857911156399e-9 10097/10092/60/71/10095/10093/10109/998/10552/10094/5879/2885/10096 13 Equine_arteritis_virus R-HSA-5663202 Diseases of signal transduction 39/341 377/10654 7.19436658649126e-11 3.3748119623904456e-9 2.213386466561665e-9 10014/8454/22938/409/399687/8826/867/10013/1387/23164/5684/6464/1956/10197/60/5296/3320/71/2335/3845/2534/408/2100/84447/1499/5699/6400/801/3066/10956/207/942/5245/2099/4609/5879/2885/5515/1027 39 Equine_arteritis_virus R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 20/341 106/10654 1.1599661264834253e-10 5.204717576221282e-9 3.413538761230401e-9 8301/409/163/1080/29978/1173/867/1213/85439/1956/1211/160/917/338/408/115548/2060/1212/1601/2885 20 Equine_arteritis_virus R-HSA-194138 Signaling by VEGF 20/341 107/10654 1.3855632412238241e-10 5.957921937262444e-9 3.907531421521574e-9 6093/387/3710/60/5296/3320/71/5063/3845/2534/9475/1499/3728/5058/801/998/5062/207/3709/5879 20 Equine_arteritis_virus R-HSA-389356 CD28 co-stimulation 12/341 33/10654 1.8483140997991783e-10 7.629840603971008e-9 5.004067225982618e-9 4067/5296/5063/2534/5058/998/5062/207/942/5879/2885/7525 12 Equine_arteritis_virus R-HSA-5620916 VxPx cargo-targeting to cilium 10/341 21/10654 2.5523304502353347e-10 1.0130788556318713e-8 6.644325827940569e-9 55763/8729/54536/8766/60412/10640/11336/149371/55770/23265 10 Equine_arteritis_virus R-HSA-190873 Gap junction degradation 8/341 12/10654 4.495639256522463e-10 1.656964183118279e-8 1.086727835317272e-8 1173/1213/1211/60/71/4646/1212/1601 8 Equine_arteritis_virus R-HSA-389359 CD28 dependent Vav1 pathway 8/341 12/10654 4.495639256522463e-10 1.656964183118279e-8 1.086727835317272e-8 5063/2534/5058/998/5062/942/5879/2885 8 Equine_arteritis_virus R-HSA-5625740 RHO GTPases activate PKNs 18/341 95/10654 9.37423756025354e-10 3.335935573166087e-8 2.1878892019030947e-8 10627/388/4637/103910/387/7534/79784/5058/4659/10398/4627/4628/4660/10971/4629/5500/389/5879 18 Equine_arteritis_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 42/341 473/10654 1.5312928812131433e-9 5.267647511373213e-8 3.454811658315969e-8 6093/163/5898/3178/1173/867/1213/4067/387/3710/6464/1956/1211/60/4914/5296/5581/160/3320/85440/71/2335/5063/3845/2534/9475/1499/3728/5058/801/998/5289/5062/207/3709/10413/2060/2099/5879/2885/7525/5515 42 Equine_arteritis_virus R-HSA-9006925 Intracellular signaling by second messengers 32/341 305/10654 2.8889331123239584e-9 9.617351522317178e-8 6.307585708741274e-8 10014/1460/27161/5684/3710/1956/10197/5296/5581/8726/2534/8394/2100/5699/7874/801/6615/192669/3066/7157/1107/1457/57521/207/942/3709/2099/1108/5879/2885/5515/1027 32 Equine_arteritis_virus R-HSA-3858494 Beta-catenin independent WNT signaling 21/341 146/10654 7.049032220227346e-9 2.273312891023319e-7 1.490963065002034e-7 409/163/27161/1173/1213/5684/387/3710/10197/1211/160/3845/1499/5699/2783/55970/801/192669/3709/1212/5879 21 Equine_arteritis_virus R-HSA-196025 Formation of annular gap junctions 7/341 11/10654 9.568004763045602e-9 2.9921760349888064e-7 1.9624328748447598e-7 1173/1213/1211/60/71/1212/1601 7 Equine_arteritis_virus R-HSA-399954 Sema3A PAK dependent Axon repulsion 8/341 16/10654 1.0443742841757133e-8 3.1699831213804e-7 2.0790484976005684e-7 1072/3320/5063/2534/5058/5062/5879/3326 8 Equine_arteritis_virus R-HSA-5683057 MAPK family signaling cascades 30/341 294/10654 1.7649641119597105e-8 5.204122752978347e-7 3.41314864357923e-7 409/27161/8826/5684/6464/1956/10197/6711/60/71/2335/5063/3845/2534/6712/408/5699/5058/801/192669/8202/998/3569/5062/5245/4609/5879/2885/5515/6709 30 Equine_arteritis_virus R-HSA-195721 Signaling by WNT 32/341 331/10654 2.131602151965162e-8 6.110592835633464e-7 4.007661355887717e-7 8454/409/163/79577/1460/27161/1173/1387/1213/5684/387/3710/10197/1211/160/7534/3845/55366/1499/5699/2783/55970/801/192669/1457/207/3709/1212/4609/5879/4221/5515 32 Equine_arteritis_virus R-HSA-2029481 FCGR activation 7/341 12/10654 2.233382193539642e-8 6.229325469548407e-7 4.0855327181962725e-7 2209/4067/917/2534/2214/2212/7525 7 Equine_arteritis_virus R-HSA-1257604 PIP3 activates AKT signaling 28/341 264/10654 2.3373325641815285e-8 6.34770317430352e-7 4.163171298528318e-7 10014/1460/27161/5684/1956/10197/5296/8726/2534/8394/2100/5699/7874/6615/192669/3066/7157/1107/1457/57521/207/942/2099/1108/5879/2885/5515/1027 28 Equine_arteritis_virus R-HSA-5626467 RHO GTPases activate IQGAPs 10/341 32/10654 3.4081714497588024e-8 8.925187187350296e-7 5.853626439684048e-7 8826/7277/999/60/71/1499/801/998/5879/4221 10 Equine_arteritis_virus R-HSA-388841 Costimulation by the CD28 family 14/341 70/10654 3.459374878817944e-8 8.925187187350296e-7 5.853626439684048e-7 4067/5296/917/5063/2534/5058/998/5062/207/942/5879/2885/7525/5515 14 Equine_arteritis_virus R-HSA-3928665 EPH-ephrin mediated repulsion of cells 12/341 51/10654 4.918507204600891e-8 1.2380242524751511e-6 8.119640905156283e-7 163/1173/1213/4067/1211/60/160/71/2534/1212/5879/7525 12 Equine_arteritis_virus R-HSA-449147 Signaling by Interleukins 38/341 461/10654 7.267051251396246e-8 1.7856183074859349e-6 1.1711062542976907e-6 8454/7124/5898/867/302/4067/5684/1072/6464/10197/4478/5296/7534/3687/3320/2335/2534/2162/1436/5699/7412/998/3569/7157/1435/3162/5062/207/1234/5478/942/3684/3586/829/4609/2885/7525/5515 38 Equine_arteritis_virus R-HSA-264876 Insulin processing 9/341 27/10654 8.935752580755902e-8 2.1445806193814167e-6 1.406533392760354e-6 4644/55763/54536/60412/10640/11336/149371/55770/23265 9 Equine_arteritis_virus R-HSA-9009391 Extra-nuclear estrogen signaling 14/341 77/10654 1.2273718516170429e-7 2.878744888338155e-6 1.888038518157317e-6 6464/1956/5296/3320/3845/2100/2783/55970/801/2770/207/2771/2099/1027 14 Equine_arteritis_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 8/341 21/10654 1.4347127521886005e-7 3.2902745783525236e-6 2.157942221420515e-6 1387/4067/5063/3845/2534/5058/5062/30835 8 Equine_arteritis_virus R-HSA-5099900 WNT5A-dependent internalization of FZD4 7/341 15/10654 1.6695727101409344e-7 3.7456500801422704e-6 2.4566024087428396e-6 409/163/1173/1213/1211/160/1212 7 Equine_arteritis_virus R-HSA-5218920 VEGFR2 mediated vascular permeability 9/341 29/10654 1.8041621426694672e-7 3.961479428159341e-6 2.598155112511685e-6 3320/5063/1499/3728/5058/801/5062/207/5879 9 Equine_arteritis_virus R-HSA-373760 L1CAM interactions 17/341 119/10654 2.1810216199148923e-7 4.689196482817019e-6 3.075431801765956e-6 163/1460/7277/1173/1213/1956/1211/4478/6711/60/160/71/6712/5058/1457/5879/6709 17 Equine_arteritis_virus R-HSA-5617833 Cilium Assembly 22/341 201/10654 4.540828821809705e-7 9.563541518586972e-6 6.272294162027154e-6 55763/7277/10013/26146/3320/8729/54536/8766/22832/60412/10640/11190/84902/11336/57787/9657/4751/149371/51134/10121/55770/23265 22 Equine_arteritis_virus R-HSA-2029485 Role of phospholipids in phagocytosis 8/341 25/10654 6.815532343746041e-7 1.3807420711048693e-5 9.055662502248377e-6 2209/3710/5296/5581/917/2214/2212/3709 8 Equine_arteritis_virus R-HSA-166520 Signaling by NTRKs 15/341 101/10654 6.823434653715924e-7 1.3807420711048693e-5 9.055662502248377e-6 163/5898/1173/1213/387/6464/1211/4914/5296/160/3845/2534/5879/2885/5515 15 Equine_arteritis_virus R-HSA-1500931 Cell-Cell communication 17/341 129/10654 7.082326393420234e-7 1.4055693919249388e-5 9.218493665929577e-6 8826/6711/999/60/5296/81/71/2534/7305/1499/3728/87/667/2316/5339/2885/6709 17 Equine_arteritis_virus R-HSA-3371511 HSF1 activation 6/341 12/10654 8.079460214135519e-7 1.57320810207318e-5 1.0317960114576243e-5 6119/6118/10013/3320/6117/3326 6 Equine_arteritis_virus R-HSA-1852241 Organelle biogenesis and maintenance 27/341 296/10654 9.037904352156572e-7 1.7272439428565892e-5 1.1328211497927243e-5 55763/7277/10013/1387/26146/3320/6742/8729/54536/8766/22832/10989/60412/801/10640/11190/84902/11336/6256/57787/9657/4751/149371/51134/10121/55770/23265 27 Equine_arteritis_virus R-HSA-109581 Apoptosis 20/341 178/10654 1.0075037834088752e-6 1.8904434626871986e-5 1.2398563305873813e-5 6093/1613/2934/10134/1829/5684/10197/999/7534/929/1499/5699/55075/7157/5062/207/8626/10971/5339/6709 20 Equine_arteritis_virus R-HSA-5357801 Programmed Cell Death 20/341 181/10654 1.3142445220169932e-6 2.4219649048598873e-5 1.588457194843847e-5 6093/1613/2934/10134/1829/5684/10197/999/7534/929/1499/5699/55075/7157/5062/207/8626/10971/5339/6709 20 Equine_arteritis_virus R-HSA-187037 Signaling by NTRK1 (TRKA) 13/341 80/10654 1.3378998217518351e-6 2.4223028351717436e-5 1.5886788280451154e-5 163/5898/1173/1213/387/6464/1211/4914/5296/160/3845/2885/5515 13 Equine_arteritis_virus R-HSA-5140745 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 6/341 13/10654 1.4601304878152486e-6 2.5980252817678215e-5 1.7039272298824043e-5 163/1173/1213/1211/160/1212 6 Equine_arteritis_virus R-HSA-6807070 PTEN Regulation 17/341 140/10654 2.2619283266913935e-6 3.914649076170416e-5 2.5674412035675007e-5 10014/1460/27161/5684/10197/8726/5699/7874/6615/192669/3066/7157/1107/1457/57521/207/1108 17 Equine_arteritis_virus R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 9/341 38/10654 2.2759587652153583e-6 3.914649076170416e-5 2.5674412035675007e-5 5898/302/1072/4478/998/5062/5478/3586/829 9 Equine_arteritis_virus R-HSA-177504 Retrograde neurotrophin signalling 6/341 14/10654 2.486565625955074e-6 4.206779878664977e-5 2.759036578928581e-5 163/1173/1213/1211/4914/160 6 Equine_arteritis_virus R-HSA-8939211 ESR-mediated signaling 22/341 223/10654 2.650043958971974e-6 4.41104091235335e-5 2.8930021487588783e-5 1025/27161/1387/6464/1956/5296/3320/3845/2100/2783/55970/801/192669/8202/2770/207/6667/2771/2099/4609/1027/3326 22 Equine_arteritis_virus R-HSA-5621481 C-type lectin receptors (CLRs) 17/341 142/10654 2.7566188150674617e-6 4.5156041542057466e-5 2.9615804479337974e-5 8454/1387/4067/5684/3710/10197/56667/5063/3845/2534/5699/5058/801/5062/9040/3709/30835 17 Equine_arteritis_virus R-HSA-1227986 Signaling by ERBB2 10/341 50/10654 3.2476567930185993e-6 5.236846578742491e-5 3.4346107202482886e-5 387/6464/1956/5581/3320/3845/2534/207/2885/7525 10 Equine_arteritis_virus R-HSA-5620920 Cargo trafficking to the periciliary membrane 10/341 51/10654 3.926380434386145e-6 6.211979513709013e-5 4.074156290610868e-5 55763/8729/54536/8766/60412/10640/11336/149371/55770/23265 10 Equine_arteritis_virus R-HSA-5637810 Constitutive Signaling by EGFRvIII 6/341 15/10654 4.032971195915735e-6 6.211979513709013e-5 4.074156290610868e-5 867/6464/1956/3320/3845/2885 6 Equine_arteritis_virus R-HSA-5637812 Signaling by EGFRvIII in Cancer 6/341 15/10654 4.032971195915735e-6 6.211979513709013e-5 4.074156290610868e-5 867/6464/1956/3320/3845/2885 6 Equine_arteritis_virus R-HSA-373753 Nephrin family interactions 7/341 23/10654 5.095961873950813e-6 7.733871549878293e-5 5.0722964163318466e-5 8826/6711/5296/81/2534/87/6709 7 Equine_arteritis_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 16/341 134/10654 5.613183533213768e-6 8.39537015402407e-5 5.5061434200708666e-5 8454/4067/5684/3710/6464/10197/5296/3845/2534/5699/5058/801/5062/3709/5879/2885 16 Equine_arteritis_virus R-HSA-190828 Gap junction trafficking 9/341 47/10654 1.4753767264371877e-5 2.0034062916883918e-4 1.313943538918437e-4 7277/1173/1213/1211/60/71/4646/1212/1601 9 Equine_arteritis_virus R-HSA-437239 Recycling pathway of L1 9/341 47/10654 1.4753767264371877e-5 2.0034062916883918e-4 1.313943538918437e-4 163/7277/1173/1213/1211/4478/60/160/71 9 Equine_arteritis_virus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 9/341 47/10654 1.4753767264371877e-5 2.0034062916883918e-4 1.313943538918437e-4 409/8826/60/71/2335/3845/408/801/5245 9 Equine_arteritis_virus R-HSA-6802949 Signaling by RAS mutants 9/341 47/10654 1.4753767264371877e-5 2.0034062916883918e-4 1.313943538918437e-4 409/8826/60/71/2335/3845/408/801/5245 9 Equine_arteritis_virus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 9/341 47/10654 1.4753767264371877e-5 2.0034062916883918e-4 1.313943538918437e-4 409/8826/60/71/2335/3845/408/801/5245 9 Equine_arteritis_virus R-HSA-9020591 Interleukin-12 signaling 9/341 47/10654 1.4753767264371877e-5 2.0034062916883918e-4 1.313943538918437e-4 5898/302/1072/4478/998/5062/5478/3586/829 9 Equine_arteritis_virus R-HSA-9649948 Signaling downstream of RAS mutants 9/341 47/10654 1.4753767264371877e-5 2.0034062916883918e-4 1.313943538918437e-4 409/8826/60/71/2335/3845/408/801/5245 9 Equine_arteritis_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 11/341 73/10654 1.850444869329494e-5 2.480076759932517e-4 1.6265701312082907e-4 22938/1025/867/387/5501/9040/5499/6667/5500/4609/4221 11 Equine_arteritis_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 6/341 19/10654 1.9609738156124534e-5 2.4984258984099404e-4 1.6386045008951367e-4 867/6464/1956/3320/3845/2885 6 Equine_arteritis_virus R-HSA-3928664 Ephrin signaling 6/341 19/10654 1.9609738156124534e-5 2.4984258984099404e-4 1.6386045008951367e-4 10627/5063/2534/5058/5062/5879 6 Equine_arteritis_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 6/341 19/10654 1.9609738156124534e-5 2.4984258984099404e-4 1.6386045008951367e-4 867/6464/1956/3320/3845/2885 6 Equine_arteritis_virus R-HSA-8964038 LDL clearance 6/341 19/10654 1.9609738156124534e-5 2.4984258984099404e-4 1.6386045008951367e-4 163/1173/1213/1211/160/338 6 Equine_arteritis_virus R-HSA-157858 Gap junction trafficking and regulation 9/341 49/10654 2.102383783009805e-5 2.637047015727883e-4 1.7295198195767326e-4 7277/1173/1213/1211/60/71/4646/1212/1601 9 Equine_arteritis_virus R-HSA-111465 Apoptotic cleavage of cellular proteins 8/341 38/10654 2.1412909342517543e-5 2.637047015727883e-4 1.7295198195767326e-4 6093/2934/10134/1829/999/1499/5339/6709 8 Equine_arteritis_virus R-HSA-8866427 VLDLR internalisation and degradation 5/341 12/10654 2.1464336174529278e-5 2.637047015727883e-4 1.7295198195767326e-4 163/1173/1213/1211/160 5 Equine_arteritis_virus R-HSA-5687128 MAPK6/MAPK4 signaling 12/341 89/10654 2.4650359996386203e-5 2.9928437077965365e-4 1.9628707712292666e-4 27161/5684/10197/5063/5699/5058/192669/8202/998/5062/4609/5879 12 Equine_arteritis_virus R-HSA-2980736 Peptide hormone metabolism 12/341 90/10654 2.763841747787226e-5 3.3166100973446716e-4 2.1752144967285023e-4 4644/55763/54536/4311/1499/60412/1636/10640/11336/149371/55770/23265 12 Equine_arteritis_virus R-HSA-202733 Cell surface interactions at the vascular wall 15/341 137/10654 3.135482715290822e-5 3.7193312208966994e-4 2.4393410598088307e-4 4067/6464/5296/3687/682/338/2335/3845/2534/960/5478/3684/3676/2885/7525 15 Equine_arteritis_virus R-HSA-4086400 PCP/CE pathway 12/341 92/10654 3.4571257552950915e-5 3.9991840517697186e-4 2.622883869122735e-4 409/163/1173/1213/5684/387/10197/1211/160/5699/1212/5879 12 Equine_arteritis_virus R-HSA-75153 Apoptotic execution phase 9/341 52/10654 3.459580843008885e-5 3.9991840517697186e-4 2.622883869122735e-4 6093/2934/10134/1829/999/1499/5062/5339/6709 9 Equine_arteritis_virus R-HSA-2424491 DAP12 signaling 7/341 30/10654 3.4876605102642895e-5 3.9991840517697186e-4 2.622883869122735e-4 6464/5296/3845/2534/7305/5879/2885 7 Equine_arteritis_virus R-HSA-389513 CTLA4 inhibitory signaling 6/341 21/10654 3.714708411560651e-5 4.2127242645391123e-4 2.7629352326587604e-4 4067/2534/207/942/7525/5515 6 Equine_arteritis_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 13/341 108/10654 3.900323162748039e-5 4.3751451129956265e-4 2.869459718131567e-4 7124/3687/3320/2335/2162/7412/3569/7157/3162/207/3684/3586/4609 13 Equine_arteritis_virus R-HSA-9607240 FLT3 Signaling 22/341 267/10654 4.6189787718894834e-5 5.125576443645105e-4 3.361633673259692e-4 409/8826/5684/6464/1956/10197/6711/60/5296/71/2335/3845/2534/6712/408/5699/801/5289/5245/2885/5515/6709 22 Equine_arteritis_virus R-HSA-912631 Regulation of signaling by CBL 6/341 22/10654 4.9710559985631965e-5 5.457584883528956e-4 3.579382986647408e-4 867/4067/5296/2534/2885/7525 6 Equine_arteritis_virus R-HSA-5633007 Regulation of TP53 Activity 16/341 160/10654 5.2706750428250336e-5 5.725617520205721e-4 3.755173465414401e-4 672/1017/6119/1460/6118/6117/7874/133746/3066/7157/1107/1457/207/8626/1108/5515 16 Equine_arteritis_virus R-HSA-2871796 FCERI mediated MAPK activation 7/341 32/10654 5.4568917160834906e-5 5.866158594789753e-4 3.84734799719483e-4 4067/6464/3845/5058/5062/5879/2885 7 Equine_arteritis_virus R-HSA-1433557 Signaling by SCF-KIT 8/341 43/10654 5.522038935148505e-5 5.87499400110645e-4 3.853142740423753e-4 867/4067/5296/3845/2534/5879/2885/7525 8 Equine_arteritis_virus R-HSA-157118 Signaling by NOTCH 20/341 235/10654 6.521126366037897e-5 6.867145316072561e-4 4.5038498962001806e-4 10014/8454/22938/409/27161/10013/1387/5684/1956/10197/7534/59/408/5699/6400/192669/3066/7157/207/4609 20 Equine_arteritis_virus R-HSA-6798695 Neutrophil degranulation 32/341 480/10654 6.598229782326554e-5 6.878154682182832e-4 4.511070441292902e-4 10097/3043/6093/25801/10092/3303/1460/2934/8826/79980/302/6280/387/3687/929/968/3320/3240/960/7305/4311/3728/7097/2040/2212/2547/5478/3684/10075/5879/3326/6709 32 Equine_arteritis_virus R-HSA-5684996 MAPK1/MAPK3 signaling 21/341 255/10654 6.924289761058987e-5 7.145867033412875e-4 4.686650859327294e-4 409/8826/5684/6464/1956/10197/6711/60/71/2335/3845/2534/6712/408/5699/801/3569/5245/2885/5515/6709 21 Equine_arteritis_virus R-HSA-447115 Interleukin-12 family signaling 9/341 57/10654 7.348646548092417e-5 7.508716076862747e-4 4.924627129154168e-4 5898/302/1072/4478/998/5062/5478/3586/829 9 Equine_arteritis_virus R-HSA-69206 G1/S Transition 14/341 131/10654 7.50280706392302e-5 7.591075382322114e-4 4.978642871106812e-4 8454/1017/6119/6118/5684/10197/6117/5699/4174/207/4171/4609/5515/1027 14 Equine_arteritis_virus R-HSA-6802957 Oncogenic MAPK signaling 10/341 71/10654 8.039298270867786e-5 8.054908558772384e-4 5.28285006455594e-4 409/8826/23164/60/71/2335/3845/408/801/5245 10 Equine_arteritis_virus R-HSA-453279 Mitotic G1-G1/S phases 15/341 149/10654 8.342725295243557e-5 8.278550485280145e-4 5.429526685062355e-4 8454/1017/6119/6118/4067/5684/10197/6117/5699/4174/207/4171/4609/5515/1027 15 Equine_arteritis_virus R-HSA-9006931 Signaling by Nuclear Receptors 23/341 299/10654 8.99915012624054e-5 8.844878981219274e-4 5.800955920975105e-4 1025/27161/1387/6464/1956/5296/3320/3845/2100/2783/55970/801/192669/8202/2770/207/6256/6667/2771/2099/4609/1027/3326 23 Equine_arteritis_virus R-HSA-5663205 Infectious disease 27/341 383/10654 9.922032089893067e-5 9.659940676197779e-4 6.335518007747013e-4 84168/163/1025/3303/6146/1173/9636/867/1213/5684/10197/1211/999/160/3320/2534/1499/5699/2547/801/5062/1234/5478/2060/5879/2885/3326 27 Equine_arteritis_virus R-HSA-114604 GPVI-mediated activation cascade 7/341 35/10654 1.0037516749319999e-4 9.681044191867513e-4 6.349358848807436e-4 388/4067/387/5296/2534/998/5879 7 Equine_arteritis_virus R-HSA-1433559 Regulation of KIT signaling 5/341 16/10654 1.0648039446398288e-4 0.0010081446521727554 6.611964620023273e-4 867/4067/2534/2885/7525 5 Equine_arteritis_virus R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 5/341 16/10654 1.0648039446398288e-4 0.0010081446521727554 6.611964620023273e-4 4067/6464/5296/2534/2885 5 Equine_arteritis_virus R-HSA-1643713 Signaling by EGFR in Cancer 6/341 25/10654 1.0878172160850751e-4 0.0010205703336361794 6.693459042513908e-4 867/6464/1956/3320/3845/2885 6 Equine_arteritis_virus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 7/341 36/10654 1.2122152584735556e-4 0.0011270325646348732 7.391696644841122e-4 409/8826/60/71/2335/3845/408 7 Equine_arteritis_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 8/341 48/10654 1.2500420181146984e-4 0.0011518244309771148 7.554295278644276e-4 867/4067/6464/5296/7534/2534/2885/7525 8 Equine_arteritis_virus R-HSA-4086398 Ca2+ pathway 9/341 62/10654 1.4397365542950094e-4 0.001310560243844053 8.595371652302387e-4 27161/3710/3845/1499/2783/55970/801/192669/3709 9 Equine_arteritis_virus R-HSA-5673001 RAF/MAP kinase cascade 20/341 249/10654 1.4477118972695935e-4 0.001310560243844053 8.595371652302387e-4 409/8826/5684/6464/1956/10197/6711/60/71/2335/3845/2534/6712/408/5699/801/5245/2885/5515/6709 20 Equine_arteritis_virus R-HSA-164952 The role of Nef in HIV-1 replication and disease pathogenesis 6/341 27/10654 1.7224471907342138e-4 0.001545709131163225 0.0010137606806792673 163/1173/160/2534/5062/5879 6 Equine_arteritis_virus R-HSA-69275 G2/M Transition 17/341 196/10654 1.8253552560173453e-4 0.0016239367450085348 0.0010650666330482333 8454/1017/7277/5684/10197/3320/5699/51512/4659/11190/7157/4660/4751/5500/10121/5515/3326 17 Equine_arteritis_virus R-HSA-453274 Mitotic G2-G2/M phases 17/341 198/10654 2.0622530669616034e-4 0.0018190129616276708 0.0011930082969467484 8454/1017/7277/5684/10197/3320/5699/51512/4659/11190/7157/4660/4751/5500/10121/5515/3326 17 Equine_arteritis_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 12/341 112/10654 2.3740180214772307e-4 0.002064473819312997 0.001353994967174885 8454/4067/5684/3710/10197/3845/2534/5699/801/5478/3709/2885 12 Equine_arteritis_virus R-HSA-8878159 Transcriptional regulation by RUNX3 11/341 96/10654 2.380546361417119e-4 0.002064473819312997 0.001353994967174885 22938/1387/5684/10197/3845/1499/5699/7157/10413/3676/4609 11 Equine_arteritis_virus R-HSA-5674135 MAP2K and MAPK activation 7/341 40/10654 2.425450103478813e-4 0.0020801420152918226 0.001364271027981071 409/8826/60/71/2335/3845/408 7 Equine_arteritis_virus R-HSA-114608 Platelet degranulation 13/341 129/10654 2.4389262000999083e-4 0.0020801420152918226 0.001364271027981071 7277/1072/81/135228/3309/9948/2335/2162/801/87/2316/5478/7273 13 Equine_arteritis_virus R-HSA-6802952 Signaling by BRAF and RAF fusions 9/341 67/10654 2.637041902750327e-4 0.002230678068556014 0.0014630008140366353 409/8826/23164/60/71/2335/3845/408/801 9 Equine_arteritis_virus R-HSA-5620912 Anchoring of the basal body to the plasma membrane 11/341 98/10654 2.857323872569759e-4 0.0023973644199121883 0.0015723228498608086 7277/3320/8766/22832/11190/84902/57787/9657/4751/51134/10121 11 Equine_arteritis_virus R-HSA-8848021 Signaling by PTK6 8/341 54/10654 2.916912695227515e-4 0.0024082031211798364 0.0015794314636052987 1017/867/387/1956/3845/207/5879/1027 8 Equine_arteritis_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 8/341 54/10654 2.916912695227515e-4 0.0024082031211798364 0.0015794314636052987 1017/867/387/1956/3845/207/5879/1027 8 Equine_arteritis_virus R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 8/341 55/10654 3.3198840521397383e-4 0.0026996780323968127 0.0017705966695544168 3303/830/7277/3320/832/829/10121/3326 8 Equine_arteritis_virus R-HSA-2173782 Binding and Uptake of Ligands by Scavenger Receptors 7/341 42/10654 3.322278198782899e-4 0.0026996780323968127 0.0017705966695544168 9332/3043/3320/338/3240/8542/23166 7 Equine_arteritis_virus R-HSA-167044 Signalling to RAS 5/341 20/10654 3.400664467595557e-4 0.0027205315740764457 0.0017842735639852659 5898/6464/4914/3845/2885 5 Equine_arteritis_virus R-HSA-8876384 Listeria monocytogenes entry into host cells 5/341 20/10654 3.400664467595557e-4 0.0027205315740764457 0.0017842735639852659 867/999/1499/2060/2885 5 Equine_arteritis_virus R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 13/341 134/10654 3.548866186590102e-4 0.0028172537727392194 0.0018477092777145227 7277/1072/81/135228/3309/9948/2335/2162/801/87/2316/5478/7273 13 Equine_arteritis_virus R-HSA-2172127 DAP12 interactions 7/341 43/10654 3.8609037581405724e-4 0.003041566930077153 0.0019948261281513766 6464/5296/3845/2534/7305/5879/2885 7 Equine_arteritis_virus R-HSA-9006936 Signaling by TGF-beta family members 11/341 102/10654 4.055059835996863e-4 0.003170319508143002 0.002079269118457722 22938/1025/867/387/5501/9040/5499/6667/5500/4609/4221 11 Equine_arteritis_virus R-HSA-445144 Signal transduction by L1 5/341 21/10654 4.3472874758578804e-4 0.0033732335902897236 0.0022123512837171483 1460/1956/5058/1457/5879 5 Equine_arteritis_virus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 11/341 103/10654 4.4127861379688054e-4 0.003398503951032692 0.002228924969924542 1956/5296/2534/8394/2100/207/942/2099/5879/2885/5515 11 Equine_arteritis_virus R-HSA-199992 trans-Golgi Network Vesicle Budding 9/341 72/10654 4.562684813135813e-4 0.0034705116974687324 0.0022761515926891015 8301/1213/1211/8729/408/9685/5286/1212/9026 9 Equine_arteritis_virus R-HSA-397795 G-protein beta:gamma signalling 6/341 32/10654 4.6071715363683755e-4 0.0034705116974687324 0.0022761515926891015 387/2783/55970/5058/998/207 6 Equine_arteritis_virus R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 6/341 32/10654 4.6071715363683755e-4 0.0034705116974687324 0.0022761515926891015 4067/3710/2534/801/3709/2885 6 Equine_arteritis_virus R-HSA-1980143 Signaling by NOTCH1 9/341 73/10654 5.060566877146112e-4 0.0037844239255179625 0.002482032419530855 10014/8454/22938/409/10013/1387/408/3066/4609 9 Equine_arteritis_virus R-HSA-3371556 Cellular response to heat stress 10/341 89/10654 5.3219276390249e-4 0.0039011437768710815 0.0025585836888291566 6119/3303/6118/10013/1387/3309/3320/6117/57521/3326 10 Equine_arteritis_virus R-HSA-5663220 RHO GTPases Activate Formins 13/341 140/10654 5.423414862184456e-4 0.0039011437768710815 0.0025585836888291566 388/7277/79980/387/60/54908/71/55143/5501/998/389/5879/5515 13 Equine_arteritis_virus R-HSA-1250196 SHC1 events in ERBB2 signaling 5/341 22/10654 5.479693909976002e-4 0.0039011437768710815 0.0025585836888291566 6464/1956/5581/3845/2885 5 Equine_arteritis_virus R-HSA-9613829 Chaperone Mediated Autophagy 5/341 22/10654 5.479693909976002e-4 0.0039011437768710815 0.0025585836888291566 3043/1080/10013/3320/3326 5 Equine_arteritis_virus R-HSA-2871809 FCERI mediated Ca+2 mobilization 6/341 33/10654 5.481258213627004e-4 0.0039011437768710815 0.0025585836888291566 4067/3710/6464/801/3709/2885 6 Equine_arteritis_virus R-HSA-68962 Activation of the pre-replicative complex 6/341 33/10654 5.481258213627004e-4 0.0039011437768710815 0.0025585836888291566 1017/6119/6118/6117/4174/4171 6 Equine_arteritis_virus R-HSA-8964043 Plasma lipoprotein clearance 6/341 33/10654 5.481258213627004e-4 0.0039011437768710815 0.0025585836888291566 163/1173/1213/1211/160/338 6 Equine_arteritis_virus R-HSA-2168880 Scavenging of heme from plasma 4/341 13/10654 5.861973090290546e-4 0.004143531663821811 0.00271755493659468 9332/3043/3240/8542 4 Equine_arteritis_virus R-HSA-3700989 Transcriptional Regulation by TP53 24/341 365/10654 6.653044540890595e-4 0.004670708820543601 0.0030633065805890816 672/1025/1017/6119/1460/6118/27161/1387/7534/6117/7874/192669/133746/3066/7157/1107/1457/57521/207/8626/10971/1108/5515/1027 24 Equine_arteritis_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 7/341 47/10654 6.753114574933206e-4 0.004708556402140482 0.0030881290968750824 10014/8454/22938/10013/1387/3066/4609 7 Equine_arteritis_virus R-HSA-8943724 Regulation of PTEN gene transcription 8/341 61/10654 6.798206433322984e-4 0.004708556402140482 0.0030881290968750824 10014/8726/6615/3066/7157/1107/57521/1108 8 Equine_herpesvirus_2 R-HSA-5357801 Programmed Cell Death 45/208 181/10654 7.986541878348989e-38 6.700708635934802e-35 4.413615248561283e-35 8837/7316/54205/841/5339/23643/7099/10018/4137/355/598/8772/56616/836/197259/330/842/331/929/581/637/317/8743/3002/5594/7186/11035/839/10059/8737/10134/329/7157/5599/8797/5595/8795/353376/8717/7431/148022/356/840/596/207 45 Equine_herpesvirus_2 R-HSA-73887 Death Receptor Signalling 41/208 141/10654 1.6570782228782247e-37 6.951443144974152e-35 4.5787687737424625e-35 8837/7316/9099/387/5584/1540/843/841/10018/7124/8517/355/8772/1147/836/3551/330/7128/25999/4615/7189/7185/7132/331/396/8743/7186/835/8878/4790/8737/8567/329/5599/5970/8797/8767/8795/8793/8717/356 41 Equine_herpesvirus_2 R-HSA-109581 Apoptosis 42/208 178/10654 2.9965038032299515e-34 8.380222303033099e-32 5.519875427002542e-32 8837/7316/54205/841/5339/23643/7099/10018/4137/355/598/8772/56616/836/842/331/929/581/637/317/8743/3002/5594/7186/839/10059/8737/10134/329/7157/5599/8797/5595/8795/353376/8717/7431/148022/356/840/596/207 42 Equine_herpesvirus_2 R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 24/208 55/10654 3.59187541222207e-27 5.839936552767203e-25 3.8466428582934343e-25 7316/351/1540/841/8517/598/1147/3551/330/7128/7189/842/834/1432/835/4790/10392/29108/329/5970/8767/837/596/58484 24 Equine_herpesvirus_2 R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 16/208 17/10654 4.16573634152908e-27 5.839936552767203e-25 3.8466428582934343e-25 8837/841/23643/7099/355/8772/929/8743/7186/8737/8797/8795/353376/8717/148022/356 16 Equine_herpesvirus_2 R-HSA-5213460 RIPK1-mediated regulated necrosis 17/208 20/10654 4.872414287171683e-27 5.839936552767203e-25 3.8466428582934343e-25 8837/7316/841/355/8772/197259/330/331/8743/7186/11035/8737/329/8797/8795/8717/356 17 Equine_herpesvirus_2 R-HSA-5218859 Regulated Necrosis 17/208 20/10654 4.872414287171683e-27 5.839936552767203e-25 3.8466428582934343e-25 8837/7316/841/355/8772/197259/330/331/8743/7186/11035/8737/329/8797/8795/8717/356 17 Equine_herpesvirus_2 R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 18/208 27/10654 3.247071304141386e-25 3.4053660302182783e-23 2.243042677202931e-23 8837/841/23643/7099/355/8772/836/842/929/8743/7186/8737/8797/8795/353376/8717/148022/356 18 Equine_herpesvirus_2 R-HSA-5357905 Regulation of TNFR1 signaling 19/208 33/10654 9.309769408996146e-25 8.678773926830852e-23 5.716525075699387e-23 7316/9099/1540/841/7124/8517/1147/3551/330/7128/25999/7185/7132/331/7186/8737/8567/329/8717 19 Equine_herpesvirus_2 R-HSA-166166 MyD88-independent TLR4 cascade 27/208 99/10654 5.2476663856547504e-24 4.002538270513032e-22 2.6363874186303773e-22 7316/351/841/23643/7099/8517/8772/1147/3551/330/7189/929/5594/1432/11035/5609/4790/8737/10392/329/5599/5970/8767/5595/353376/5515/148022 27 Equine_herpesvirus_2 R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 27/208 99/10654 5.2476663856547504e-24 4.002538270513032e-22 2.6363874186303773e-22 7316/351/841/23643/7099/8517/8772/1147/3551/330/7189/929/5594/1432/11035/5609/4790/8737/10392/329/5599/5970/8767/5595/353376/5515/148022 27 Equine_herpesvirus_2 R-HSA-5675482 Regulation of necroptotic cell death 15/208 18/10654 1.0650450786507996e-23 7.446440174900175e-22 4.904812862207629e-22 8837/7316/841/355/8772/330/331/8743/7186/8737/329/8797/8795/8717/356 15 Equine_herpesvirus_2 R-HSA-75893 TNF signaling 20/208 43/10654 1.666693340993543e-23 1.0756582408412172e-21 7.08513363580251e-22 7316/9099/1540/841/7124/8517/8772/1147/3551/330/7128/25999/7185/7132/331/7186/8737/8567/329/8717 20 Equine_herpesvirus_2 R-HSA-8948216 Collagen chain trimerization 20/208 44/10654 3.0040971007654074e-23 1.8003124768158405e-21 1.1858278029337134e-21 1288/256076/1281/1301/1280/1290/1289/1293/1284/1302/1292/1291/1286/1287/1285/1278/131873/1282/1294/1277 20 Equine_herpesvirus_2 R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 28/208 129/10654 6.865589515321094e-22 3.8401530689029315e-20 2.529427716170929e-20 7316/351/841/23643/7099/8517/8772/1147/3551/330/4615/7189/929/5594/1432/11035/5609/4790/8737/10392/329/5599/5970/8767/5595/353376/5515/148022 28 Equine_herpesvirus_2 R-HSA-168898 Toll-like Receptor Cascades 30/208 155/10654 7.414087357012151e-22 3.8877620578332465e-20 2.5607867515995913e-20 7316/351/841/23643/7099/8517/8772/1147/3551/330/4615/7189/929/7098/5594/1432/11035/5609/4790/8737/10392/329/5599/5970/8767/5595/5289/353376/5515/148022 30 Equine_herpesvirus_2 R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12/208 12/10654 2.2329650912399255e-21 1.1020339479707632e-19 7.258864847683968e-20 64135/843/841/7706/8517/8772/1147/3551/84282/57506/8737/23586 12 Equine_herpesvirus_2 R-HSA-2022090 Assembly of collagen fibrils and other multimeric structures 21/208 61/10654 2.802863035616164e-21 1.3064456038233122e-19 8.605281249698749e-20 1288/5339/256076/1281/1301/1280/1290/1289/1293/1284/1302/1292/1291/1286/1287/1285/1278/131873/1282/1294/1277 21 Equine_herpesvirus_2 R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 24/208 94/10654 1.0962808278545554e-20 4.840945339841958e-19 3.1886284466683744e-19 7316/351/841/8517/8772/1147/3551/330/7189/7098/5594/1432/11035/5609/4790/8737/10392/329/5599/5970/8767/5595/5515/148022 24 Equine_herpesvirus_2 R-HSA-168638 NOD1/2 Signaling Pathway 17/208 36/10654 2.794576954432372e-20 1.1393830692117738e-18 7.5048756205530545e-19 7316/1540/841/8517/1147/3551/330/7128/7189/842/834/1432/835/10392/329/8767/837 17 Equine_herpesvirus_2 R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 16/208 30/10654 2.851852735810161e-20 1.1393830692117738e-18 7.5048756205530545e-19 7316/9099/1540/7124/8517/1147/3551/330/7128/7185/7132/331/7186/8737/329/8717 16 Equine_herpesvirus_2 R-HSA-109606 Intrinsic Pathway for Apoptosis 19/208 53/10654 9.624233774031732e-20 3.670332789278465e-18 2.41757068486443e-18 54205/841/10018/598/56616/836/842/331/581/637/317/3002/5594/7157/5599/5595/840/596/207 19 Equine_herpesvirus_2 R-HSA-3371378 Regulation by c-FLIP 11/208 11/10654 1.2063678916785024e-19 4.048570644473055e-18 2.6667079710787944e-18 8837/841/355/8772/8743/7186/8737/8797/8795/8717/356 11 Equine_herpesvirus_2 R-HSA-5218900 CASP8 activity is inhibited 11/208 11/10654 1.2063678916785024e-19 4.048570644473055e-18 2.6667079710787944e-18 8837/841/355/8772/8743/7186/8737/8797/8795/8717/356 11 Equine_herpesvirus_2 R-HSA-69416 Dimerization of procaspase-8 11/208 11/10654 1.2063678916785024e-19 4.048570644473055e-18 2.6667079710787944e-18 8837/841/355/8772/8743/7186/8737/8797/8795/8717/356 11 Equine_herpesvirus_2 R-HSA-1442490 Collagen degradation 20/208 64/10654 2.381759918304881e-19 7.685756044068443e-18 5.062445170486084e-18 1288/256076/1281/1301/1280/1290/1289/1293/1284/1302/1292/1291/1286/1287/1285/1278/131873/1282/1294/1277 20 Equine_herpesvirus_2 R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 23/208 97/10654 4.508310574962709e-19 1.4009157675532268e-17 9.227536264543554e-18 7316/351/23643/7099/8517/1147/3551/4615/7189/929/5594/1432/5609/4790/10392/5599/5970/8767/5595/5289/353376/5515/148022 23 Equine_herpesvirus_2 R-HSA-1650814 Collagen biosynthesis and modifying enzymes 20/208 67/10654 6.686340115951738e-19 2.0035140561726817e-17 1.319672391306264e-17 1288/256076/1281/1301/1280/1290/1289/1293/1284/1302/1292/1291/1286/1287/1285/1278/131873/1282/1294/1277 20 Equine_herpesvirus_2 R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 21/208 78/10654 9.433948813246312e-19 2.729338984246088e-17 1.7977579408182626e-17 64135/7316/351/1540/843/841/7706/8517/8772/1147/3551/7128/7189/84282/57506/7186/4790/8737/23586/5970/9474 21 Equine_herpesvirus_2 R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 22/208 92/10654 2.2555076544773396e-18 6.307903073688293e-17 4.1548825214056255e-17 7316/351/23643/7099/8517/1147/3551/4615/7189/929/5594/1432/5609/4790/10392/5599/5970/8767/5595/353376/5515/148022 22 Equine_herpesvirus_2 R-HSA-937041 IKK complex recruitment mediated by RIP1 14/208 25/10654 2.78129937904015e-18 7.385143680069846e-17 4.864438155745146e-17 7316/23643/7099/8517/1147/3551/330/7189/929/11035/8737/329/353376/148022 14 Equine_herpesvirus_2 R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 22/208 93/10654 2.9047644987163875e-18 7.385143680069846e-17 4.864438155745146e-17 7316/351/23643/7099/8517/1147/3551/4615/7189/929/5594/1432/5609/4790/10392/5599/5970/8767/5595/353376/5515/148022 22 Equine_herpesvirus_2 R-HSA-975155 MyD88 dependent cascade initiated on endosome 22/208 93/10654 2.9047644987163875e-18 7.385143680069846e-17 4.864438155745146e-17 7316/351/23643/7099/8517/1147/3551/4615/7189/929/5594/1432/5609/4790/10392/5599/5970/8767/5595/353376/5515/148022 22 Equine_herpesvirus_2 R-HSA-3000178 ECM proteoglycans 20/208 76/10654 1.0787584203928232e-17 2.6619950432634667e-16 1.7533999093072204e-16 351/1288/256076/1281/1280/1290/1289/3685/1293/1284/1292/1291/1286/1287/1285/1278/3690/131873/1282/1277 20 Equine_herpesvirus_2 R-HSA-1474290 Collagen formation 21/208 90/10654 2.390729675072261e-17 5.730920563958934e-16 3.774836329061465e-16 1288/5339/256076/1281/1301/1280/1290/1289/1293/1284/1302/1292/1291/1286/1287/1285/1278/131873/1282/1294/1277 21 Equine_herpesvirus_2 R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 16/208 44/10654 6.42843750460945e-17 1.4981830739909249e-15 9.868215467602227e-16 843/8794/355/8738/834/581/637/317/835/839/7157/8797/8795/8793/472/58484 16 Equine_herpesvirus_2 R-HSA-933542 TRAF6 mediated NF-kB activation 13/208 24/10654 8.499515295638316e-17 1.9273225224433912e-15 1.2694866373286248e-15 64135/351/7706/8517/1147/3551/7189/84282/57506/7186/4790/23586/5970 13 Equine_herpesvirus_2 R-HSA-216083 Integrin cell surface interactions 20/208 85/10654 1.1919893923700213e-16 2.631787105785389e-15 1.7335025789314715e-15 1288/256076/1281/1280/1290/1289/3685/1293/1284/1292/1291/1286/1287/1285/1278/3690/131873/1282/1294/1277 20 Equine_herpesvirus_2 R-HSA-5689896 Ovarian tumor domain proteases 15/208 38/10654 1.4327686981499945e-16 3.0822895839688345e-15 2.0302390459615305e-15 64135/7316/5728/387/7706/8517/7128/7189/84282/57506/8737/10392/23586/7157/8767 15 Equine_herpesvirus_2 R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 20/208 95/10654 1.2254347834325957e-15 2.5076580080486534e-14 1.6517413640619067e-14 7316/351/23643/7099/8517/1147/3551/4615/7189/929/5594/1432/5609/4790/10392/5599/5970/8767/5595/5515 20 Equine_herpesvirus_2 R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 20/208 95/10654 1.2254347834325957e-15 2.5076580080486534e-14 1.6517413640619067e-14 7316/351/23643/7099/8517/1147/3551/4615/7189/929/5594/1432/5609/4790/10392/5599/5970/8767/5595/5515 20 Equine_herpesvirus_2 R-HSA-5357786 TNFR1-induced proapoptotic signaling 10/208 13/10654 1.7622412479978178e-15 3.520286683500402e-14 2.3187384842076548e-14 9099/1540/841/7124/8772/7128/7132/7186/8737/8717 10 Equine_herpesvirus_2 R-HSA-375165 NCAM signaling for neurite out-growth 17/208 63/10654 2.0737759481438934e-15 4.046274466262155e-14 2.6651955269903158e-14 256076/1281/1280/1290/1289/1293/1284/1292/1291/6714/5594/1286/1287/5595/1285/131873/1282 17 Equine_herpesvirus_2 R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 20/208 98/10654 2.3278472094216138e-15 4.3401417971216315e-14 2.858759730868649e-14 7316/351/23643/7099/8517/1147/3551/4615/7189/929/5594/1432/5609/4790/10392/5599/5970/8767/5595/5515 20 Equine_herpesvirus_2 R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 20/208 98/10654 2.3278472094216138e-15 4.3401417971216315e-14 2.858759730868649e-14 7316/351/23643/7099/8517/1147/3551/4615/7189/929/5594/1432/5609/4790/10392/5599/5970/8767/5595/5515 20 Equine_herpesvirus_2 R-HSA-2562578 TRIF-mediated programmed cell death 9/208 10/10654 3.4106955113258807e-15 6.22081203044003e-14 4.097517490723312e-14 841/23643/7099/8772/929/11035/8737/353376/148022 9 Equine_herpesvirus_2 R-HSA-3000171 Non-integrin membrane-ECM interactions 16/208 59/10654 1.3086064927778613e-14 2.336001803065161e-13 1.538675047499165e-13 1288/1281/1301/1280/1290/1289/3685/1284/1302/1286/1287/1285/1278/3690/1282/1277 16 Equine_herpesvirus_2 R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 11/208 20/10654 1.7370270556943998e-14 3.03617854109917e-13 1.999866675963947e-13 7316/8517/1147/3551/330/7189/7098/11035/8737/329/148022 11 Equine_herpesvirus_2 R-HSA-449147 Signaling by Interleukins 38/208 461/10654 2.4359029526501714e-14 4.1337400130915405e-13 2.722807235271386e-13 7316/351/11009/4478/7124/8517/6657/598/1147/836/3551/4615/7189/7132/5783/3553/834/3320/5594/1432/5609/8878/4790/10392/4609/7157/5599/5970/8767/5595/5515/1278/7431/356/596/4170/3598/207 38 Equine_herpesvirus_2 R-HSA-419037 NCAM1 interactions 14/208 42/10654 2.4634922604836353e-14 4.1337400130915405e-13 2.722807235271386e-13 256076/1281/1280/1290/1289/1293/1284/1292/1291/1286/1287/1285/131873/1282 14 Equine_herpesvirus_2 R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 9/208 12/10654 7.253196070827468e-14 1.1932218634165186e-12 7.859500386345554e-13 843/8738/834/317/835/839/7157/472/58484 9 Equine_herpesvirus_2 R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 10/208 17/10654 1.1193181616663451e-13 1.805976803150122e-12 1.1895587750502655e-12 8517/1147/3551/4615/7098/11035/4790/8737/5970/148022 10 Equine_herpesvirus_2 R-HSA-186797 Signaling by PDGF 15/208 58/10654 1.9547657241580652e-13 3.094431023714371e-12 2.0382363558748442e-12 256076/1281/1280/1290/1289/1293/1284/1292/1291/6714/1286/1287/1285/131873/1282 15 Equine_herpesvirus_2 R-HSA-111461 Cytochrome c-mediated apoptotic response 9/208 13/10654 2.3176382949389753e-13 3.6009232026922227e-12 2.3718520562240973e-12 54205/56616/836/842/331/317/5594/5595/840 9 Equine_herpesvirus_2 R-HSA-5260271 Diseases of Immune System 11/208 24/10654 2.410756611540306e-13 3.611829994789852e-12 2.3790361298095125e-12 23643/7099/8517/1147/3551/4615/929/7098/4790/5970/148022 11 Equine_herpesvirus_2 R-HSA-5602358 Diseases associated with the TLR signaling cascade 11/208 24/10654 2.410756611540306e-13 3.611829994789852e-12 2.3790361298095125e-12 23643/7099/8517/1147/3551/4615/929/7098/4790/5970/148022 11 Equine_herpesvirus_2 R-HSA-111471 Apoptotic factor-mediated response 10/208 18/10654 2.4758937075938857e-013 3.6443417906513506e-12 2.400450963041163e-12 54205/56616/836/842/331/581/317/5594/5595/840 10 Equine_herpesvirus_2 R-HSA-1474228 Degradation of the extracellular matrix 21/208 140/10654 2.8403454190484864e-13 4.053420289963383e-12 2.6699023301308276e-12 1288/256076/1281/1301/1280/1290/1289/836/1293/1284/1302/1292/1291/1286/1287/1285/1278/131873/1282/1294/1277 21 Equine_herpesvirus_2 R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 37/208 473/10654 2.85043858293015e-13 4.053420289963383e-12 2.6699023301308276e-12 2475/7316/387/5900/1956/256076/1281/5725/1301/1280/1290/1289/3685/1293/1284/1302/581/1292/1291/6714/1111/3320/5594/1286/1432/1287/5595/1285/5289/5515/1278/3690/1213/131873/1282/207/1277 37 Equine_herpesvirus_2 R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 17/208 85/10654 4.4845098581838583e-13 6.0685544693810604e-12 3.997228651182557e-12 7316/351/8517/1147/3551/4615/7189/5594/1432/5609/4790/10392/5599/5970/8767/5595/5515 17 Equine_herpesvirus_2 R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 17/208 85/10654 4.4845098581838583e-13 6.0685544693810604e-12 3.997228651182557e-12 7316/351/8517/1147/3551/4615/7189/5594/1432/5609/4790/10392/5599/5970/8767/5595/5515 17 Equine_herpesvirus_2 R-HSA-975871 MyD88 cascade initiated on plasma membrane 17/208 85/10654 4.4845098581838583e-13 6.0685544693810604e-12 3.997228651182557e-12 7316/351/8517/1147/3551/4615/7189/5594/1432/5609/4790/10392/5599/5970/8767/5595/5515 17 Equine_herpesvirus_2 R-HSA-2214320 Anchoring fibril formation 9/208 15/10654 1.5682361056776188e-12 2.0884922105770197e-11 1.3756457067347535e-11 1288/1284/1286/1287/1285/1278/1282/1294/1277 9 Equine_herpesvirus_2 R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 10/208 21/10654 1.896226378923328e-12 2.4858342686198002e-11 1.6373665278532023e-11 8517/1147/3551/4615/7098/11035/4790/8737/5970/148022 10 Equine_herpesvirus_2 R-HSA-193639 p75NTR signals via NF-kB 9/208 16/10654 3.5242626661888294e-12 4.549009810665274e-11 2.996336679755685e-11 7316/5584/3551/4615/7189/8878/4790/5970/8767 9 Equine_herpesvirus_2 R-HSA-3700989 Transcriptional Regulation by TP53 31/208 365/10654 3.63702758728129e-12 4.623433554134852e-11 3.0453580276278745e-11 2475/7316/54205/1616/5728/9099/843/8794/641/355/8738/1025/834/80196/581/637/317/1111/1432/835/839/7157/8797/1107/8795/8793/472/5515/1027/58484/207 31 Equine_herpesvirus_2 R-HSA-450294 MAP kinase activation 14/208 64/10654 1.528678014081634e-11 1.9142699310664046e-10 1.2608891710806878e-10 7316/8517/1147/3551/7189/5594/1432/5609/4790/10392/5599/8767/5595/5515 14 Equine_herpesvirus_2 R-HSA-448424 Interleukin-17 signaling 14/208 72/10654 8.320415511123782e-11 1.0265924432107137e-9 6.761947590309575e-10 7316/8517/1147/3551/7189/5594/1432/5609/4790/10392/5599/8767/5595/5515 14 Equine_herpesvirus_2 R-HSA-111458 Formation of apoptosome 7/208 11/10654 3.019854687902088e-10 3.619511547356931e-9 2.3840958062384903e-9 54205/56616/842/331/317/5594/5595 7 Equine_herpesvirus_2 R-HSA-9627069 Regulation of the apoptosome activity 7/208 11/10654 3.019854687902088e-10 3.619511547356931e-9 2.3840958062384903e-9 54205/56616/842/331/317/5594/5595 7 Equine_herpesvirus_2 R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 10/208 33/10654 4.055994063474731e-10 4.792928196134224e-9 3.157000568308723e-9 7316/351/8517/1147/3551/7189/4790/10392/5970/8767 10 Equine_herpesvirus_2 R-HSA-193704 p75 NTR receptor-mediated signalling 15/208 97/10654 5.204331147883347e-10 6.064491434825178e-9 3.994552416138534e-9 7316/387/5584/10018/836/3551/4615/7189/396/835/8878/4790/5599/5970/8767 15 Equine_herpesvirus_2 R-HSA-2243919 Crosslinking of collagen fibrils 8/208 18/10654 6.828632159857648e-10 7.848249838521325e-9 5.1694764007574116e-9 1288/1284/1286/1287/1285/1278/1282/1277 8 Equine_herpesvirus_2 R-HSA-264870 Caspase-mediated cleavage of cytoskeletal proteins 7/208 12/10654 7.128017615181949e-10 8.081630782618454e-9 5.323199499246833e-9 841/5339/4137/836/839/7431/840 7 Equine_herpesvirus_2 R-HSA-1474244 Extracellular matrix organization 25/208 301/10654 8.580700609063913e-10 9.598943748006165e-9 6.322621501415514e-9 351/1288/5339/256076/1281/1301/1280/1290/1289/3685/836/1293/1284/1302/1292/1291/1286/1287/1285/1278/3690/131873/1282/1294/1277 25 Equine_herpesvirus_2 R-HSA-5607764 CLEC7A (Dectin-1) signaling 15/208 101/10654 9.341976474917922e-10 1.031305034533702e-8 6.792988433977713e-9 7316/84433/841/8517/1147/3551/8915/7189/3553/6714/9020/10892/4790/29108/5970 15 Equine_herpesvirus_2 R-HSA-209543 p75NTR recruits signalling complexes 7/208 13/10654 1.5189158213514871e-9 1.655026459888179e-8 1.0901309722618328e-8 7316/5584/3551/4615/7189/8878/8767 7 Equine_herpesvirus_2 R-HSA-622312 Inflammasomes 8/208 20/10654 1.9008008979847686e-9 2.0445794274477192e-8 1.3467212839973056e-8 351/598/834/4790/29108/5970/596/58484 8 Equine_herpesvirus_2 R-HSA-5688426 Deubiquitination 24/208 297/10654 3.3182155651674124e-9 3.524028935665138e-8 2.321203426666078e-8 64135/7316/5728/9099/387/1540/7706/8517/330/7128/7189/84282/8678/367/57506/7186/8737/10392/4609/23586/329/7157/8767/8314 24 Equine_herpesvirus_2 R-HSA-8874081 MET activates PTK2 signaling 9/208 30/10654 3.4766116157976415e-9 3.6460964320677767e-8 2.4016067082812654e-8 1281/1301/1280/1290/1289/1302/6714/1278/1277 9 Equine_herpesvirus_2 R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 7/208 16/10654 9.633169604932659e-9 9.978060862393211e-8 6.572337937088558e-8 7316/23643/7099/7189/929/353376/148022 7 Equine_herpesvirus_2 R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 9/208 34/10654 1.1910909399661343e-8 1.218689388575106e-7 8.027249595407195e-8 64135/7316/1540/7706/7128/84282/57506/23586/9474 9 Equine_herpesvirus_2 R-HSA-446652 Interleukin-1 family signaling 16/208 140/10654 1.268591862299178e-8 1.2823476776735064e-7 8.446553300026233e-8 7316/351/8517/1147/3551/4615/7189/5783/3553/834/8878/4790/10392/5599/5970/8767 16 Equine_herpesvirus_2 R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 7/208 17/10654 1.6106325932719157e-8 1.6087151735180204e-7 1.0596267060999446e-7 7316/23643/7099/7189/929/353376/148022 7 Equine_herpesvirus_2 R-HSA-6804757 Regulation of TP53 Degradation 9/208 36/10654 2.0666921851632155e-8 2.0399467568846328e-7 1.343669841746982e-7 2475/7316/1616/9099/80196/7157/472/5515/207 9 Equine_herpesvirus_2 R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 14/208 108/10654 2.0970745148816527e-8 2.0458668813787286e-7 1.3475693027085282e-7 7124/6657/598/3553/3320/4609/7157/1278/7431/356/596/4170/3598/207 14 Equine_herpesvirus_2 R-HSA-6806003 Regulation of TP53 Expression and Degradation 9/208 37/10654 2.6851548663874364e-8 2.5894769343667346e-7 1.7056337626780448e-7 2475/7316/1616/9099/80196/7157/472/5515/207 9 Equine_herpesvirus_2 R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 11/208 63/10654 3.053788912214472e-8 2.911510110622661e-7 1.9177502140102844e-7 7316/8517/1147/3551/4615/7098/11035/4790/8737/5970/148022 11 Equine_herpesvirus_2 R-HSA-111465 Apoptotic cleavage of cellular proteins 9/208 38/10654 3.4594379318704865e-8 3.261200477347571e-7 2.148083872539332e-7 841/5339/4137/836/839/10134/329/7431/840 9 Equine_herpesvirus_2 R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 6/208 12/10654 4.318144445827943e-8 4.025470211166272e-7 2.651492203578561e-7 8794/355/7157/8797/8795/8793 6 Equine_herpesvirus_2 R-HSA-75153 Apoptotic execution phase 10/208 52/10654 5.016847682703675e-8 4.6254233030641575e-7 3.0466686332208554e-7 841/5339/4137/836/839/10059/10134/329/7431/840 10 Equine_herpesvirus_2 R-HSA-8875878 MET promotes cell motility 9/208 41/10654 7.0670387165488e-8 6.444832046939613e-7 4.2450747439223335e-7 1281/1301/1280/1290/1289/1302/6714/1278/1277 9 Equine_herpesvirus_2 R-HSA-3000157 Laminin interactions 8/208 30/10654 7.465679535253018e-8 6.735166806534711e-7 4.4363121177225064e-7 1288/3685/1284/1286/1287/1285/1282/1294 8 Equine_herpesvirus_2 R-HSA-209560 NF-kB is activated and signals survival 6/208 13/10654 7.88921832899323e-8 7.041546997899276e-7 4.638118278523455e-7 7316/3551/7189/8878/4790/5970 6 Equine_herpesvirus_2 R-HSA-9020702 Interleukin-1 signaling 13/208 103/10654 9.398442559412585e-8 8.300308744575955e-7 5.467238053951919e-7 7316/351/8517/1147/3551/4615/7189/3553/8878/4790/10392/5970/8767 13 Equine_herpesvirus_2 R-HSA-5621481 C-type lectin receptors (CLRs) 15/208 142/10654 1.0623091833407844e-7 9.284139633572064e-7 6.115266680415699e-7 7316/84433/841/8517/1147/3551/8915/7189/3553/6714/9020/10892/4790/29108/5970 15 Equine_herpesvirus_2 R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 7/208 23/10654 1.8376614175636698e-7 1.5894824013772359e-6 1.0469584853184227e-6 7316/8517/7189/5609/10392/5599/8767 7 Equine_herpesvirus_2 R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 14/208 134/10654 3.282216538387183e-7 2.8099792609253538e-6 1.850873987812321e-6 7316/84433/8517/1147/3551/8915/7189/5594/5609/10892/4790/5599/5970/5595 14 Equine_herpesvirus_2 R-HSA-202424 Downstream TCR signaling 12/208 98/10654 4.157420261426914e-7 3.5233086861991723e-6 2.3207290135556936e-6 7316/84433/5728/8517/1147/3551/8915/7189/10892/4790/5970/8767 12 Equine_herpesvirus_2 R-HSA-9612973 Autophagy 13/208 119/10654 5.212358450125329e-7 4.373168739655151e-6 2.8805138803324187e-6 2475/7316/11315/8678/6714/3320/84557/8878/84971/5289/7431/9474/81631 13 Equine_herpesvirus_2 R-HSA-3000170 Syndecan interactions 7/208 27/10654 6.228888462622639e-7 5.174294475386528e-6 3.4081984813724706e-6 1281/1290/1289/3685/1278/3690/1277 7 Equine_herpesvirus_2 R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 6/208 18/10654 7.864569233661767e-7 6.468993712786492e-6 4.260989522881762e-6 7316/23643/7099/929/353376/148022 6 Equine_herpesvirus_2 R-HSA-933541 TRAF6 mediated IRF7 activation 7/208 29/10654 1.0590445038390288e-6 8.62658581282471e-6 5.682149867301892e-6 64135/7706/7189/84282/57506/7186/23586 7 Equine_herpesvirus_2 R-HSA-6806834 Signaling by MET 10/208 79/10654 2.887776940384693e-6 2.3296585124834203e-5 1.5344968559736474e-5 7316/1281/1301/1280/1290/1289/1302/6714/1278/1277 10 Equine_herpesvirus_2 R-HSA-202403 TCR signaling 12/208 119/10654 3.3911908552925963e-6 2.709722978657608e-5 1.784837292259261e-5 7316/84433/5728/8517/1147/3551/8915/7189/10892/4790/5970/8767 12 Equine_herpesvirus_2 R-HSA-1257604 PIP3 activates AKT signaling 18/208 264/10654 3.993635588252489e-6 3.1610002439092816e-5 2.0820840951663917e-5 51564/2475/7316/5728/1956/1147/4615/7189/842/331/6714/5594/7157/5595/1107/5515/1027/207 18 Equine_herpesvirus_2 R-HSA-2871837 FCERI mediated NF-kB activation 10/208 82/10654 4.075259608110735e-6 3.195460571219539e-5 2.1047823849071672e-5 7316/84433/8517/1147/3551/8915/7189/10892/4790/5970 10 Equine_herpesvirus_2 R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 11/208 102/10654 4.542652346776739e-6 3.52896788791267e-5 2.3244566101927755e-5 7316/8742/7124/1147/330/7132/8718/9020/7186/329/356 11 Equine_herpesvirus_2 R-HSA-918233 TRAF3-dependent IRF activation pathway 5/208 14/10654 4.689216692062686e-6 3.6094062427895356e-5 2.377439655560512e-5 64135/7706/84282/57506/23586 5 Equine_herpesvirus_2 R-HSA-450302 activated TAK1 mediates p38 MAPK activation 6/208 24/10654 5.169933648704693e-6 3.872834224342176e-5 2.5509541029792896e-5 7316/8517/7189/1432/10392/8767 6 Equine_herpesvirus_2 R-HSA-8940973 RUNX2 regulates osteoblast differentiation 6/208 24/10654 5.169933648704693e-6 3.872834224342176e-5 2.5509541029792896e-5 5925/6714/367/5594/5595/1277 6 Equine_herpesvirus_2 R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 6/208 24/10654 5.169933648704693e-6 3.872834224342176e-5 2.5509541029792896e-5 1956/5594/5595/596/1027/207 6 Equine_herpesvirus_2 R-HSA-1169091 Activation of NF-kappaB in B cells 9/208 67/10654 5.559260206909891e-6 4.127627711148141e-5 2.7187811910830863e-5 7316/84433/8517/1147/3551/8915/10892/4790/5970 9 Equine_herpesvirus_2 R-HSA-5689880 Ub-specific processing proteases 16/208 220/10654 6.183640367041565e-6 4.550942340305151e-5 2.9976095962112848e-5 64135/7316/5728/9099/1540/8517/330/7189/8678/367/7186/8737/4609/23586/329/7157 16 Equine_herpesvirus_2 R-HSA-844456 The NLRP3 inflammasome 5/208 15/10654 6.9224777648401665e-6 4.964067388633248e-5 3.269726339668095e-5 351/834/4790/29108/5970 5 Equine_herpesvirus_2 R-HSA-937039 IRAK1 recruits IKK complex 5/208 15/10654 6.9224777648401665e-6 4.964067388633248e-5 3.269726339668095e-5 7316/8517/1147/3551/7189 5 Equine_herpesvirus_2 R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 5/208 15/10654 6.9224777648401665e-6 4.964067388633248e-5 3.269726339668095e-5 7316/8517/1147/3551/7189 5 Equine_herpesvirus_2 R-HSA-1295596 Spry regulation of FGF signaling 5/208 16/10654 9.909726124926857e-6 6.9867732931207e-5 4.602039996096063e-5 7316/6714/5594/5595/5515 5 Equine_herpesvirus_2 R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 5/208 16/10654 9.909726124926857e-6 6.9867732931207e-5 4.602039996096063e-5 7316/8517/1147/3551/4790 5 Equine_herpesvirus_2 R-HSA-1169408 ISG15 antiviral mechanism 9/208 72/10654 1.0171474831650634e-5 7.111556153129068e-5 4.684231830365424e-5 8672/7316/1982/7706/1977/1973/23586/5595/1981 9 Equine_herpesvirus_2 R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 14/208 182/10654 1.2668221178265635e-5 8.783997990549478e-5 5.785833943966471e-5 51564/1616/142/9994/8517/641/9971/11315/367/7428/7157/5970/1107/10210 14 Equine_herpesvirus_2 R-HSA-5633007 Regulation of TP53 Activity 13/208 160/10654 1.4495528267691162e-5 9.968646079174495e-5 6.566136618238015e-5 2475/7316/1616/9099/641/80196/1111/1432/7157/1107/472/5515/207 13 Equine_herpesvirus_2 R-HSA-1632852 Macroautophagy 10/208 95/10654 1.544147064958716e-5 1.0532840548783437e-4 6.937759598659186e-5 2475/7316/8678/6714/84557/8878/84971/5289/9474/81631 10 Equine_herpesvirus_2 R-HSA-5205647 Mitophagy 6/208 29/10654 1.6817511102780722e-5 1.1378945012284699e-4 7.495070737656944e-5 7316/6714/84557/8878/9474/81631 6 Equine_herpesvirus_2 R-HSA-2990846 SUMOylation 14/208 188/10654 1.83036195069888e-5 1.2285389413090882e-4 8.092126518879259e-5 51564/1616/142/9994/8517/641/9971/11315/367/7428/7157/5970/1107/10210 14 Equine_herpesvirus_2 R-HSA-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 5/208 18/10654 1.8828357216160816e-5 1.2537295003459465e-4 8.258051410596849e-5 8742/330/9020/7186/329 5 Equine_herpesvirus_2 R-HSA-2262752 Cellular responses to stress 24/208 479/10654 2.050517411533717e-5 1.3546331561234556e-4 8.922682478700385e-5 2475/7316/54205/4217/5925/1783/3309/9588/51143/367/3320/5594/1432/5609/7428/4790/1051/1410/7157/5599/5970/5595/472/1027 24 Equine_herpesvirus_2 R-HSA-114452 Activation of BH3-only proteins 6/208 30/10654 2.068222868774006e-5 1.3556554585167116e-4 8.929416168637771e-5 10018/637/7157/5599/596/207 6 Equine_herpesvirus_2 R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 9/208 80/10654 2.4218844462659096e-5 1.5751636049744948e-4 1.0375269965643432e-4 8672/7316/1982/7706/1977/1973/23586/5595/1981 9 Equine_herpesvirus_2 R-HSA-3000480 Scavenging by Class A Receptors 5/208 19/10654 2.514891092038395e-5 1.623072020169395e-4 1.0690832577491152e-4 1281/1284/1278/1282/1277 5 Equine_herpesvirus_2 R-HSA-450341 Activation of the AP-1 family of transcription factors 4/208 10/10654 2.7032506753698386e-5 1.718202512602496e-4 1.1317437038031622e-4 5594/1432/5599/5595 4 Equine_herpesvirus_2 R-HSA-5602498 MyD88 deficiency (TLR2/4) 4/208 10/10654 2.7032506753698386e-5 1.718202512602496e-4 1.1317437038031622e-4 23643/7099/4615/929 4 Equine_herpesvirus_2 R-HSA-2559583 Cellular Senescence 14/208 195/10654 2.7581624545490932e-5 1.739923533358413e-4 1.1460508813915901e-4 7316/4217/5925/5594/1432/5609/4790/1051/7157/5599/5970/5595/472/1027 14 Equine_herpesvirus_2 R-HSA-9006925 Intracellular signaling by second messengers 18/208 305/10654 2.8777989730815244e-5 1.801845774936865e-4 1.1868377540202674e-4 51564/2475/7316/5728/1956/1147/4615/7189/842/331/6714/5594/7157/5595/1107/5515/1027/207 18 Equine_herpesvirus_2 R-HSA-8941326 RUNX2 regulates bone development 6/208 32/10654 3.055294805281975e-5 1.8988091419493163e-4 1.2507054758464226e-4 5925/6714/367/5594/5595/1277 6 Equine_herpesvirus_2 R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 9/208 83/10654 3.263681961612948e-5 2.0052841838710976e-4 1.3208383370332178e-4 7316/84433/8517/1147/3551/8915/10892/4790/5970 9 Equine_herpesvirus_2 R-HSA-8953897 Cellular responses to external stimuli 24/208 493/10654 3.274421134569015e-5 2.0052841838710976e-4 1.3208383370332178e-4 2475/7316/54205/4217/5925/1783/3309/9588/51143/367/3320/5594/1432/5609/7428/4790/1051/1410/7157/5599/5970/5595/472/1027 24 Equine_herpesvirus_2 R-HSA-5603041 IRAK4 deficiency (TLR2/4) 4/208 11/10654 4.183094932343419e-5 2.506869034454378e-4 1.6512216838197709e-4 23643/7099/4615/929 4 Equine_herpesvirus_2 R-HSA-8934903 Receptor Mediated Mitophagy 4/208 11/10654 4.183094932343419e-5 2.506869034454378e-4 1.6512216838197709e-4 6714/84557/9474/81631 4 Equine_herpesvirus_2 R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 4/208 11/10654 4.183094932343419e-5 2.506869034454378e-4 1.6512216838197709e-4 7316/7189/7098/148022 4 Equine_herpesvirus_2 R-HSA-445144 Signal transduction by L1 5/208 21/10654 4.26312527440574e-5 2.536710712926536e-4 1.67087776712431e-4 1956/3685/5594/5595/3690 5 Equine_herpesvirus_2 R-HSA-5205685 Pink/Parkin Mediated Mitophagy 5/208 22/10654 5.4298965321311744e-5 3.2082275989141234e-4 2.113191756389078e-4 7316/84557/8878/9474/81631 5 Equine_herpesvirus_2 R-HSA-8848021 Signaling by PTK6 7/208 54/10654 7.946547090969394e-5 4.6299673675856407e-4 3.049661712543079e-4 7316/387/120892/1956/10657/1027/207 7 Equine_herpesvirus_2 R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 7/208 54/10654 7.946547090969394e-5 4.6299673675856407e-4 3.049661712543079e-4 7316/387/120892/1956/10657/1027/207 7 Equine_herpesvirus_2 R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 5/208 25/10654 1.044481751932931e-4 6.043587516356753e-4 3.980783446568339e-4 2475/1147/842/1027/207 5 Equine_herpesvirus_2 R-HSA-198323 AKT phosphorylates targets in the cytosol 4/208 14/10654 1.211691079388874e-4 6.963074079501817e-4 4.58642982465147e-4 1147/842/1027/207 4 Equine_herpesvirus_2 R-HSA-9009391 Extra-nuclear estrogen signaling 8/208 77/10654 1.2226589540689653e-4 6.978305186828992e-4 4.5964622333419746e-4 1956/6714/3320/5594/5595/596/1027/207 8 Equine_herpesvirus_2 R-HSA-1236975 Antigen processing-Cross presentation 9/208 99/10654 1.3133529648108342e-4 7.445291469434391e-4 4.904056234179857e-4 7316/23643/7099/8517/1147/3685/3551/4615/929 9 Equine_herpesvirus_2 R-HSA-2173782 Binding and Uptake of Ligands by Scavenger Receptors 6/208 42/10654 1.5033449478957022e-4 8.465143699895934e-4 5.575811357437256e-4 1281/1284/3320/1278/1282/1277 6 Equine_herpesvirus_2 R-HSA-166520 Signaling by NTRKs 9/208 101/10654 1.5320992303257427e-4 8.569541694955321e-4 5.64457611172642e-4 387/5900/581/6714/5594/1432/5595/5515/1213 9 Equine_herpesvirus_2 R-HSA-187037 Signaling by NTRK1 (TRKA) 8/208 80/10654 1.6022253252096917e-4 8.902430780469745e-4 5.863843121192668e-4 387/5900/6714/5594/1432/5595/5515/1213 8 Equine_herpesvirus_2 R-HSA-1236974 ER-Phagosome pathway 8/208 83/10654 2.0739207406489534e-4 0.0011447496719766263 7.540224299450835e-4 7316/23643/7099/8517/1147/3551/4615/929 8 Equine_herpesvirus_2 R-HSA-205043 NRIF signals cell death from the nucleus 4/208 16/10654 2.13647874082473e-4 0.0011715723291189205 7.716899476663111e-4 7316/7189/8878/5599 4 Equine_herpesvirus_2 R-HSA-5654732 Negative regulation of FGFR3 signaling 5/208 29/10654 2.190964487391971e-4 0.0011936488343648466 7.862312753798938e-4 7316/6714/5594/5595/5515 5 Equine_herpesvirus_2 R-HSA-199418 Negative regulation of the PI3K/AKT network 9/208 110/10654 2.929083611459857e-4 0.0015854846129127872 0.001044325226496723 5728/1956/4615/7189/6714/5594/5595/5515/207 9 Equine_herpesvirus_2 R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 5/208 31/10654 3.0369228916883427e-4 0.0016229161185519233 0.0010689805686465838 5594/1432/5599/5595/5515 5 Equine_herpesvirus_2 R-HSA-5654733 Negative regulation of FGFR4 signaling 5/208 31/10654 3.0369228916883427e-4 0.0016229161185519233 0.0010689805686465838 7316/6714/5594/5595/5515 5 Equine_herpesvirus_2 R-HSA-983705 Signaling by the B Cell Receptor (BCR) 9/208 112/10654 3.351754782607689e-4 0.0017798242168404119 0.0011723326188334687 7316/84433/8517/1147/3551/8915/10892/4790/5970 9 Equine_herpesvirus_2 R-HSA-1227986 Signaling by ERBB2 6/208 50/10654 4.000194943962828e-4 0.002110794690556486 0.001390335879232363 7316/387/1956/6714/3320/207 6 Equine_herpesvirus_2 R-HSA-6807070 PTEN Regulation 10/208 140/10654 4.0965166433154293e-4 0.0021284505328763802 0.001401965409648202 51564/2475/7316/5728/331/5594/7157/5595/1107/207 10 Equine_herpesvirus_2 R-HSA-2559585 Oncogene Induced Senescence 5/208 33/10654 4.1097614579973016e-4 0.0021284505328763802 0.001401965409648202 7316/5925/5594/7157/5595 5 Equine_herpesvirus_2 R-HSA-5654726 Negative regulation of FGFR1 signaling 5/208 33/10654 4.1097614579973016e-4 0.0021284505328763802 0.001401965409648202 7316/6714/5594/5595/5515 5 Equine_herpesvirus_2 R-HSA-5663202 Diseases of signal transduction 18/208 377/10654 4.1804999669034455e-4 0.0021518033571975405 0.0014173474217786949 51564/2475/7316/5728/1956/10018/11160/1147/842/6714/3320/5594/4609/5595/5515/3690/1027/207 18 Equine_herpesvirus_2 R-HSA-187687 Signalling to ERKs 5/208 34/10654 4.742664337794109e-4 0.002411572957217732 0.001588452170553051 5900/6714/5594/1432/5595 5 Equine_herpesvirus_2 R-HSA-5654727 Negative regulation of FGFR2 signaling 5/208 34/10654 4.742664337794109e-4 0.002411572957217732 0.001588452170553051 7316/6714/5594/5595/5515 5 Equine_herpesvirus_2 R-HSA-373760 L1CAM interactions 9/208 119/10654 5.247290359815956e-4 0.0026520943445093896 0.0017468785281568654 1956/4478/3685/6714/5594/7430/5595/3690/1213 9 Equine_herpesvirus_2 R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 4/208 20/10654 5.349439028787635e-4 0.00268753254200768 0.00177022092033628 581/637/7157/472 4 Equine_herpesvirus_2 R-HSA-8878166 Transcriptional regulation by RUNX2 9/208 121/10654 5.926766364214782e-4 0.0029598553449858346 0.0019495941987548624 7316/5925/581/6714/367/5594/5595/207/1277 9 Equine_herpesvirus_2 R-HSA-204998 Cell death signalling via NRAGE, NRIF and NADE 7/208 76/10654 6.83026309935404e-4 0.0033908820948864143 0.0022335024149242426 7316/10018/836/7189/835/8878/5599 7 Equine_herpesvirus_2 R-HSA-4420097 VEGFA-VEGFR2 Pathway 8/208 99/10654 6.899875676930967e-4 0.003405291584085342 0.0022429936411075897 2475/387/3685/6714/3320/1432/3690/207 8 Equine_herpesvirus_2 R-HSA-198753 ERK/MAPK targets 4/208 22/10654 7.833339975381121e-4 0.0038210303717120704 0.0025168319994339585 5594/1432/5595/5515 4 Equine_herpesvirus_2 R-HSA-9613829 Chaperone Mediated Autophagy 4/208 22/10654 7.833339975381121e-4 0.0038210303717120704 0.0025168319994339585 7316/11315/3320/7431 4 Equine_herpesvirus_2 R-HSA-2219528 PI3K/AKT Signaling in Cancer 8/208 101/10654 7.879195755472782e-4 0.003821182218983621 0.002516932018024467 2475/5728/1956/1147/842/6714/1027/207 8 Equine_herpesvirus_2 R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 8/208 103/10654 8.967341535761871e-4 0.004323907786496673 0.002848066730958852 1956/4615/7189/6714/5594/5595/5515/207 8 Equine_herpesvirus_2 R-HSA-76009 Platelet Aggregation (Plug Formation) 5/208 39/10654 9.067483312601497e-4 0.004347210571012947 0.0028634157829267883 6714/1278/3690/207/1277 5 Equine_herpesvirus_2 R-HSA-5654741 Signaling by FGFR3 5/208 40/10654 0.0010200508488634426 0.004862628762479706 0.003202910859170498 7316/6714/5594/5595/5515 5 Foot.and.mouth_disease_virus R-HSA-168898 Toll-like Receptor Cascades 73/338 155/10654 3.316678658106944e-69 2.945210648398966e-66 1.675795532517193e-66 7322/54106/8454/6500/23643/51135/1147/64127/330/3665/7311/1432/3725/11035/8945/23118/1326/329/246330/7187/351/23291/10333/841/7099/8517/8772/4615/81793/929/9641/7098/7100/4790/114609/6885/353376/7323/7334/3656/7316/6195/7097/57162/3551/79155/10454/7321/8737/10392/7335/5970/4792/8767/7096/57161/3661/695/4793/3654/4791/29110/7189/51284/7314/6233/51311/10010/5515/148022/3146/257397/4214 73 Foot.and.mouth_disease_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 67/338 129/10654 3.833306382449067e-67 1.701988033807386e-64 9.684142439871329e-65 7322/8454/6500/23643/51135/1147/64127/330/3665/7311/1432/3725/11035/8945/23118/1326/329/246330/7187/351/23291/10333/841/7099/8517/8772/4615/929/9641/4790/114609/6885/353376/7323/7334/3656/7316/6195/7097/57162/3551/79155/10454/7321/8737/10392/7335/5970/4792/8767/7096/57161/3661/695/4793/3654/4791/29110/7189/7314/6233/10010/5515/148022/3146/257397/4214 67 Foot.and.mouth_disease_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 55/338 78/10654 7.76635710384972e-66 2.298841702739517e-63 1.3080180385431109e-63 7322/1147/7128/3665/7311/55593/84282/9636/1387/54476/79671/5094/7187/351/843/841/7706/8517/8772/84166/9641/7186/4790/80143/7323/9474/64135/7316/3440/1540/3551/3456/7321/54941/8737/5970/4792/83737/3661/9140/4793/9246/4791/29110/7189/57506/51191/7314/6233/79132/10010/3093/3146/4214/23586 55 Foot.and.mouth_disease_virus R-HSA-166166 MyD88-independent TLR4 cascade 56/338 99/10654 7.6913675771422885e-59 1.3659868817004705e-56 7.772329341112208e-57 7322/8454/6500/23643/1147/64127/330/3665/7311/1432/3725/11035/8945/23118/1326/329/7187/351/23291/841/7099/8517/8772/929/9641/4790/6885/353376/7323/7334/3656/7316/6195/3551/79155/10454/7321/8737/10392/7335/5970/4792/8767/3661/4793/3654/4791/29110/7189/7314/6233/10010/5515/148022/3146/257397 56 Foot.and.mouth_disease_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 56/338 99/10654 7.6913675771422885e-59 1.3659868817004705e-56 7.772329341112208e-57 7322/8454/6500/23643/1147/64127/330/3665/7311/1432/3725/11035/8945/23118/1326/329/7187/351/23291/841/7099/8517/8772/929/9641/4790/6885/353376/7323/7334/3656/7316/6195/3551/79155/10454/7321/8737/10392/7335/5970/4792/8767/3661/4793/3654/4791/29110/7189/7314/6233/10010/5515/148022/3146/257397 56 Foot.and.mouth_disease_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 53/338 94/10654 1.4609331583562478e-55 2.162181074367247e-53 1.2302595017736823e-53 7322/8454/6500/1147/64127/330/3665/7311/1432/3725/11035/8945/23118/1326/329/7187/351/23291/841/8517/8772/9641/7098/4790/6885/7323/7334/3656/7316/6195/3551/79155/10454/7321/8737/10392/7335/5970/4792/8767/3661/4793/3654/4791/29110/7189/7314/6233/10010/5515/148022/3146/257397 53 Foot.and.mouth_disease_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 51/338 93/10654 1.350321272984392e-52 1.4988566130126752e-50 8.528344882006688e-51 54106/8454/6500/23643/51135/1147/64127/3665/7311/1432/3725/8945/23118/1326/246330/351/23291/7099/8517/4615/929/4790/6885/353376/7334/3656/7316/6195/57162/3551/79155/10454/10392/7335/5970/4792/8767/57161/4793/3654/4791/7189/51284/7314/6233/51311/5515/148022/3146/257397/4214 51 Foot.and.mouth_disease_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 51/338 93/10654 1.350321272984392e-52 1.4988566130126752e-50 8.528344882006688e-51 54106/8454/6500/23643/51135/1147/64127/3665/7311/1432/3725/8945/23118/1326/246330/351/23291/7099/8517/4615/929/4790/6885/353376/7334/3656/7316/6195/57162/3551/79155/10454/10392/7335/5970/4792/8767/57161/4793/3654/4791/7189/51284/7314/6233/51311/5515/148022/3146/257397/4214 51 Foot.and.mouth_disease_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 51/338 97/10654 2.5735323884850056e-51 2.4128071662272643e-49 1.372863252476395e-49 54106/8454/6500/23643/51135/1147/64127/3665/7311/1432/3725/8945/23118/1326/246330/351/23291/7099/8517/4615/929/4790/6885/353376/7334/3656/7316/6195/57162/3551/79155/10454/10392/7335/5970/4792/8767/57161/4793/3654/4791/7189/51284/7314/6233/51311/5515/148022/3146/257397/4214 51 Foot.and.mouth_disease_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 50/338 92/10654 2.717125187192865e-51 2.4128071662272643e-49 1.372863252476395e-49 54106/8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/351/23291/7099/8517/4615/929/4790/6885/353376/7334/3656/7316/6195/57162/3551/79155/10454/10392/7335/5970/4792/8767/57161/4793/3654/4791/7189/51284/7314/6233/51311/5515/148022/3146/257397/4214 50 Foot.and.mouth_disease_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 50/338 95/10654 2.4435582348091405e-50 1.8082330937587638e-48 1.028866625182796e-48 8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/351/23291/10333/7099/8517/4615/929/4790/114609/6885/7334/3656/7316/6195/7097/57162/3551/79155/10454/10392/7335/5970/4792/8767/7096/57161/695/4793/3654/4791/7189/7314/6233/5515/3146/257397/4214 50 Foot.and.mouth_disease_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 50/338 95/10654 2.4435582348091405e-50 1.8082330937587638e-48 1.028866625182796e-48 8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/351/23291/10333/7099/8517/4615/929/4790/114609/6885/7334/3656/7316/6195/7097/57162/3551/79155/10454/10392/7335/5970/4792/8767/7096/57161/695/4793/3654/4791/7189/7314/6233/5515/3146/257397/4214 50 Foot.and.mouth_disease_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 50/338 98/10654 1.9810632073557875e-49 1.2565600915228139e-047 7.149701800983295e-48 8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/351/23291/10333/7099/8517/4615/929/4790/114609/6885/7334/3656/7316/6195/7097/57162/3551/79155/10454/10392/7335/5970/4792/8767/7096/57161/695/4793/3654/4791/7189/7314/6233/5515/3146/257397/4214 50 Foot.and.mouth_disease_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 50/338 98/10654 1.9810632073557875e-49 1.2565600915228139e-047 7.149701800983295e-48 8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/351/23291/10333/7099/8517/4615/929/4790/114609/6885/7334/3656/7316/6195/7097/57162/3551/79155/10454/10392/7335/5970/4792/8767/7096/57161/695/4793/3654/4791/7189/7314/6233/5515/3146/257397/4214 50 Foot.and.mouth_disease_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 31/338 34/10654 4.854955943537807e-44 2.874133918574382e-42 1.635353580981156e-42 7322/7128/7311/55593/84282/9636/54476/79671/5094/7187/7706/84166/9641/7323/9474/64135/7316/1540/7321/54941/83737/3661/9140/9246/29110/57506/51191/7314/6233/3093/23586 31 Foot.and.mouth_disease_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 44/338 85/10654 6.918353834850818e-44 3.413054558526404e-42 1.9419940589054927e-42 8454/6500/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/351/23291/8517/4615/81793/7100/4790/6885/7334/3656/7316/6195/57162/3551/79155/10454/10392/7335/5970/4792/8767/57161/4793/3654/4791/7189/7314/6233/5515/3146/257397/4214 44 Foot.and.mouth_disease_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 44/338 85/10654 6.918353834850818e-44 3.413054558526404e-42 1.9419940589054927e-42 8454/6500/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/351/23291/8517/4615/81793/7100/4790/6885/7334/3656/7316/6195/57162/3551/79155/10454/10392/7335/5970/4792/8767/57161/4793/3654/4791/7189/7314/6233/5515/3146/257397/4214 44 Foot.and.mouth_disease_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 44/338 85/10654 6.918353834850818e-44 3.413054558526404e-42 1.9419940589054927e-42 8454/6500/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/351/23291/8517/4615/81793/7100/4790/6885/7334/3656/7316/6195/57162/3551/79155/10454/10392/7335/5970/4792/8767/57161/4793/3654/4791/7189/7314/6233/5515/3146/257397/4214 44 Foot.and.mouth_disease_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 29/338 30/10654 3.055184026273467e-43 1.4278965343846518e-41 8.124589100339413e-42 7124/1147/330/7128/7311/7132/23118/329/81858/9099/27005/8517/10616/331/7186/56957/6885/8717/7316/1540/3551/7185/10454/8737/55072/7375/7314/6233/257397 29 Foot.and.mouth_disease_virus R-HSA-73887 Death Receptor Signalling 49/338 141/10654 2.1961328827014235e-38 9.75082999919432e-37 5.548125177350965e-37 7124/355/1147/330/7128/7311/7132/4804/23118/329/81858/9099/843/841/27005/8517/8772/4615/10616/331/7186/56957/4790/6885/8717/7316/5584/1540/4803/3551/7185/8743/10454/3066/8737/5970/4792/8767/55072/8795/356/3654/7189/7375/8878/7314/6233/8797/257397 49 Foot.and.mouth_disease_virus R-HSA-75893 TNF signaling 31/338 43/10654 9.637019894424149e-38 4.07508269821364e-36 2.31868147835769e-36 7124/1147/330/7128/7311/7132/23118/329/81858/9099/841/27005/8517/8772/10616/331/7186/56957/6885/8717/7316/1540/3551/7185/10454/8737/55072/7375/7314/6233/257397 31 Foot.and.mouth_disease_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 33/338 55/10654 5.13513179140936e-36 2.07272592307796e-34 1.1793604114241594e-34 1147/64127/330/7128/7311/1432/23118/29108/329/596/351/841/8517/4790/6885/7334/3656/7316/1540/3551/10454/10392/7335/5970/8767/83737/3654/4791/7189/7314/6233/257397/3326 33 Foot.and.mouth_disease_virus R-HSA-5688426 Deubiquitination 63/338 297/10654 5.442386966093789e-35 2.1012346199527324e-33 1.1955815760755235e-33 100287144/672/100287478/9960/100287441/64127/330/7128/7311/55593/3091/84282/3416/329/100287513/11274/7187/6502/9099/8295/27005/7706/8517/728386/7186/645836/56957/6885/64135/7316/5728/1540/993/79155/7874/10454/7321/100287404/100287327/8737/10392/7157/4792/8767/9986/8237/100287178/63891/7189/7375/9817/57506/100287205/4303/4609/7314/6233/100287364/377630/4193/100287238/392188/23586 63 Foot.and.mouth_disease_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 26/338 33/10654 1.4611686818398663e-33 5.190071157895205e-32 2.953098809613204e-32 1147/64127/7311/23118/351/8517/4790/6885/7334/3656/7316/3551/10454/10392/7335/5970/4792/8767/4793/3654/4791/7189/7314/6233/3146/257397 26 Foot.and.mouth_disease_virus R-HSA-5357905 Regulation of TNFR1 signaling 26/338 33/10654 1.4611686818398663e-33 5.190071157895205e-32 2.953098809613204e-32 7124/1147/330/7128/7311/7132/329/81858/9099/841/27005/8517/10616/331/7186/56957/8717/7316/1540/3551/7185/8737/55072/7375/7314/6233 26 Foot.and.mouth_disease_virus R-HSA-9020702 Interleukin-1 signaling 39/338 103/10654 2.5202505095954003e-32 8.607624817387368e-31 4.897652812169199e-31 8454/6500/51135/1147/64127/7311/8945/23118/1326/246330/351/23291/8517/4615/4790/6885/7334/3656/7316/4215/57162/3551/79155/10454/10392/7335/5970/4792/8767/57161/4793/3654/4791/7189/8878/7314/6233/3146/257397 39 Foot.and.mouth_disease_virus R-HSA-168638 NOD1/2 Signaling Pathway 26/338 36/10654 7.977007961301645e-32 2.6235492850503183e-30 1.4927734196587875e-30 1147/64127/330/7128/7311/1432/23118/329/841/8517/6885/7334/3656/7316/1540/3551/10454/10392/7335/8767/83737/3654/7189/7314/6233/257397 26 Foot.and.mouth_disease_virus R-HSA-5260271 Diseases of Immune System 22/338 24/10654 1.4218580185064279e-31 4.353827311840372e-30 2.4772843879603826e-30 23643/51135/1147/7187/10333/7099/8517/4615/81793/929/7098/7100/4790/114609/7097/3551/5970/4792/7096/695/4791/148022 22 Foot.and.mouth_disease_virus R-HSA-5602358 Diseases associated with the TLR signaling cascade 22/338 24/10654 1.4218580185064279e-31 4.353827311840372e-30 2.4772843879603826e-30 23643/51135/1147/7187/10333/7099/8517/4615/81793/929/7098/7100/4790/114609/7097/3551/5970/4792/7096/695/4791/148022 22 Foot.and.mouth_disease_virus R-HSA-937041 IKK complex recruitment mediated by RIP1 22/338 25/10654 1.1511939369232135e-30 3.407534053292712e-29 1.9388529463969913e-29 7322/23643/1147/330/7311/11035/329/7099/8517/929/353376/7323/7334/7316/3551/7321/8737/7335/7189/7314/6233/148022 22 Foot.and.mouth_disease_virus R-HSA-449147 Signaling by Interleukins 70/338 461/10654 2.945217732029688e-29 8.218295316405528e-28 4.676128202791197e-28 8454/6500/51135/8660/7124/1147/2308/64127/7311/7132/3091/1432/3725/7291/8945/23118/1326/596/246330/351/23291/8517/6657/1438/3576/4615/1437/3667/3320/4790/6885/2309/7334/3656/7316/6195/4215/57162/3551/79155/6773/10454/10392/3569/7157/7335/5970/4792/8767/57161/356/1026/207/5478/4793/3627/3654/4791/29110/7189/6772/1439/8878/4609/7314/6233/5515/4582/3146/257397 70 Foot.and.mouth_disease_virus R-HSA-5689880 Ub-specific processing proteases 50/338 220/10654 2.961547861767758e-29 8.218295316405528e-28 4.676128202791197e-28 100287144/100287478/9960/100287441/330/7311/3091/3416/329/100287513/11274/6502/9099/8295/27005/8517/728386/7186/645836/6885/64135/7316/5728/1540/993/7874/10454/100287404/100287327/8737/7157/4792/9986/8237/100287178/63891/7189/7375/9817/100287205/4303/4609/7314/6233/100287364/377630/4193/100287238/392188/23586 50 Foot.and.mouth_disease_virus R-HSA-450294 MAP kinase activation 30/338 64/10654 1.8745733351920208e-28 5.0443064292439836e-27 2.870160130437544e-27 8454/6500/1147/64127/7311/1432/3725/8945/23118/1326/23291/8517/4790/6885/7334/3656/7316/6195/3551/79155/10454/10392/7335/8767/3654/7189/7314/6233/5515/257397 30 Foot.and.mouth_disease_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 19/338 20/10654 3.9653955362641707e-28 1.0356680106478187e-26 5.892847855748613e-27 7322/1147/330/7311/11035/329/8517/7098/7323/7334/7316/3551/7321/8737/7335/7189/7314/6233/148022 19 Foot.and.mouth_disease_virus R-HSA-446652 Interleukin-1 family signaling 40/338 140/10654 1.2051362447393243e-27 3.0576028152243423e-26 1.7397455563154158e-26 8454/6500/51135/1147/64127/7311/8945/23118/1326/246330/351/23291/8517/4615/4790/6885/7334/3656/7316/4215/57162/3551/79155/10454/10392/7335/5970/4792/8767/57161/4793/3654/4791/29110/7189/8878/7314/6233/3146/257397 40 Foot.and.mouth_disease_virus R-HSA-448424 Interleukin-17 signaling 30/338 72/10654 1.5131174338859594e-26 3.7323563369187e-25 2.123673591418891e-25 8454/6500/1147/64127/7311/1432/3725/8945/23118/1326/23291/8517/4790/6885/7334/3656/7316/6195/3551/79155/10454/10392/7335/8767/3654/7189/7314/6233/5515/257397 30 Foot.and.mouth_disease_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 34/338 101/10654 2.7829106757454825e-26 6.678985621789158e-25 3.800276313962537e-25 7322/8454/6500/1147/7311/5170/8945/23118/10892/29108/23291/841/8517/4790/6885/7334/7316/3551/10454/7321/9020/7335/5970/4792/84433/997/8915/4791/7189/6714/7314/6233/257397/5580 34 Foot.and.mouth_disease_virus R-HSA-5213460 RIPK1-mediated regulated necrosis 18/338 20/10654 1.216400243221514e-25 2.769649784565909e-24 1.5759031491128929e-24 355/330/7311/11035/329/841/8772/331/7186/8717/7316/8743/8737/8795/356/7314/6233/8797 18 Foot.and.mouth_disease_virus R-HSA-5218859 Regulated Necrosis 18/338 20/10654 1.216400243221514e-25 2.769649784565909e-24 1.5759031491128929e-24 355/330/7311/11035/329/841/8772/331/7186/8717/7316/8743/8737/8795/356/7314/6233/8797 18 Foot.and.mouth_disease_virus R-HSA-5689896 Ovarian tumor domain proteases 23/338 38/10654 1.628871482545507e-25 3.616094691251025e-24 2.0575218726890618e-24 64127/7128/7311/55593/84282/7187/7706/8517/56957/64135/7316/5728/79155/7321/8737/10392/7157/8767/7189/57506/7314/6233/23586 23 Foot.and.mouth_disease_virus R-HSA-5675482 Regulation of necroptotic cell death 17/338 18/10654 3.9306917937723145e-25 8.513303202121501e-24 4.8439847522739685e-24 355/330/7311/329/841/8772/331/7186/8717/7316/8743/8737/8795/356/7314/6233/8797 17 Foot.and.mouth_disease_virus R-HSA-193639 p75NTR signals via NF-kB 16/338 16/10654 7.426057499538153e-25 1.5700807284737807e-23 8.93360300696319e-24 7311/4804/4615/4790/7316/5584/4803/3551/5970/4792/8767/3654/7189/8878/7314/6233 16 Foot.and.mouth_disease_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 27/338 63/10654 2.1414405145292915e-24 4.422323667213979e-23 2.5162581321274418e-23 1147/3665/7311/11035/1387/81030/6737/8517/4615/7098/4790/5591/7316/1499/3551/22954/8737/5970/4792/3661/4793/4791/29110/3428/7314/6233/148022 27 Foot.and.mouth_disease_virus R-HSA-2871837 FCERI mediated NF-kB activation 29/338 82/10654 2.9006837226426455e-23 5.85410714933334e-22 3.3309286767188273e-22 7322/8454/6500/1147/7311/5170/8945/23118/10892/23291/8517/5588/4790/6885/7334/7316/3551/10454/7321/7335/5970/4792/84433/997/8915/7189/7314/6233/257397 29 Foot.and.mouth_disease_virus R-HSA-5621481 C-type lectin receptors (CLRs) 36/338 142/10654 5.506881367441342e-23 1.0866912565084249e-21 6.183165044144664e-22 7322/8454/6500/1147/7311/5170/8945/23118/10892/29108/1387/23291/841/8517/4790/6885/7334/7316/3551/10454/7321/9020/7335/5970/4792/84433/997/8915/4791/7189/6714/7314/6233/4582/257397/5580 36 Foot.and.mouth_disease_virus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 18/338 24/10654 7.675728402144522e-23 1.4502227278945396e-21 8.25162291831886e-22 64127/7311/1432/23118/8517/6885/7334/3656/7316/10454/10392/7335/8767/3654/7189/7314/6233/257397 18 Foot.and.mouth_disease_virus R-HSA-933542 TRAF6 mediated NF-kB activation 18/338 24/10654 7.675728402144522e-23 1.4502227278945396e-21 8.25162291831886e-22 1147/84282/351/7706/8517/7186/4790/64135/3551/5970/4792/4793/4791/7189/57506/3146/4214/23586 18 Foot.and.mouth_disease_virus R-HSA-913531 Interferon Signaling 41/338 199/10654 2.4215615301286367e-22 4.4798888307379775e-21 2.5490121369775126e-21 6041/3665/7311/4939/9636/2537/5610/11274/8638/6737/7706/10379/4940/91543/3437/7334/7316/3440/3456/6773/4938/3454/3430/3661/2316/2633/4734/9246/3434/5495/54739/6772/51191/3433/3659/7314/4600/4599/6233/5580/23586 41 Foot.and.mouth_disease_virus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 15/338 16/10654 3.802210412433796e-22 6.89053642090043e-21 3.920646612176632e-21 23643/7311/23118/7099/929/6885/353376/3656/7316/10454/7189/7314/6233/148022/257397 15 Foot.and.mouth_disease_virus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 17/338 23/10654 1.907663668948674e-21 3.388010676052845e-20 1.9277443391481336e-20 64127/7311/23118/8517/6885/7334/3656/7316/10454/10392/7335/8767/3654/7189/7314/6233/257397 17 Foot.and.mouth_disease_virus R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 15/338 17/10654 3.1398939558758435e-21 5.361972755418748e-20 3.050909106923897e-20 23643/355/841/7099/8772/929/7186/353376/8717/8743/8737/8795/356/8797/148022 15 Foot.and.mouth_disease_virus R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 15/338 17/10654 3.1398939558758435e-21 5.361972755418748e-20 3.050909106923897e-20 23643/7311/23118/7099/929/6885/353376/3656/7316/10454/7189/7314/6233/148022/257397 15 Foot.and.mouth_disease_virus R-HSA-5357801 Programmed Cell Death 38/338 181/10654 4.534602949984149e-21 7.597598904879103e-20 4.32295812510902e-20 23643/6093/355/330/7311/7161/11035/329/596/841/7099/5588/8772/331/929/10000/7186/353376/8717/51765/7316/1499/1029/8743/8737/7157/8795/356/207/8626/5366/208/7314/6233/8797/148022/3146/5580 38 Foot.and.mouth_disease_virus R-HSA-202424 Downstream TCR signaling 29/338 98/10654 9.09115716944625e-21 1.4949902900867165e-19 8.506345889540352e-20 7322/8454/6500/1147/7311/5170/8945/23118/10892/23291/8517/5588/4790/6885/7334/7316/5728/3551/7321/7335/5970/4792/8767/84433/997/8915/7189/7314/6233 29 Foot.and.mouth_disease_virus R-HSA-937039 IRAK1 recruits IKK complex 14/338 15/10654 1.1706378628380769e-20 1.8237305652635303e-19 1.037684532155636e-19 1147/7311/246330/8517/7334/7316/57162/3551/7335/57161/3654/7189/7314/6233 14 Foot.and.mouth_disease_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 14/338 15/10654 1.1706378628380769e-20 1.8237305652635303e-19 1.037684532155636e-19 54106/51135/3665/7311/4615/7334/7316/7335/3654/7189/51284/7314/6233/51311 14 Foot.and.mouth_disease_virus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 14/338 15/10654 1.1706378628380769e-20 1.8237305652635303e-19 1.037684532155636e-19 1147/7311/246330/8517/7334/7316/57162/3551/7335/57161/3654/7189/7314/6233 14 Foot.and.mouth_disease_virus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 16/338 21/10654 1.307805673928298e-20 2.002295583531601e-19 1.1392862495201145e-19 1147/11035/81030/8517/4615/7098/4790/3551/8737/5970/4792/3661/4793/4791/29110/148022 16 Foot.and.mouth_disease_virus R-HSA-909733 Interferon alpha/beta signaling 25/338 69/10654 1.662779127660002e-20 2.502623500613698e-19 1.423967852411777e-19 6041/3665/4939/9636/2537/11274/8638/10379/4940/91543/3437/3440/3456/6773/4938/3454/3430/3661/3434/54739/6772/3433/3659/4600/4599 25 Foot.and.mouth_disease_virus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 15/338 18/10654 1.830317713427278e-20 2.7088702158723715e-19 1.5413201797282342e-19 23643/3665/7311/7187/7099/929/9641/353376/7316/3661/29110/7314/6233/10010/148022 15 Foot.and.mouth_disease_virus R-HSA-209543 p75NTR recruits signalling complexes 13/338 13/10654 2.629979081265001e-20 3.7070181335925727e-19 2.1092564060270685e-19 7311/4804/4615/7316/5584/4803/3551/8767/3654/7189/8878/7314/6233 13 Foot.and.mouth_disease_virus R-HSA-209560 NF-kB is activated and signals survival 13/338 13/10654 2.629979081265001e-20 3.7070181335925727e-19 2.1092564060270685e-19 7311/4804/4790/7316/4803/3551/5970/4792/3654/7189/8878/7314/6233 13 Foot.and.mouth_disease_virus R-HSA-5357786 TNFR1-induced proapoptotic signaling 13/338 13/10654 2.629979081265001e-20 3.7070181335925727e-19 2.1092564060270685e-19 7124/7128/7132/9099/841/27005/8772/7186/56957/8717/1540/8737/7375 13 Foot.and.mouth_disease_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 14/338 16/10654 9.098948173834276e-20 1.2624790591195058e-18 7.183380137237587e-19 8454/6500/1147/7311/8945/1326/23291/8517/4790/7316/3551/79155/7314/6233 14 Foot.and.mouth_disease_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 32/338 134/10654 1.1074310052477676e-19 1.5129211271692579e-18 8.608370567108153e-19 7322/8454/6500/1147/7311/5170/3725/8945/23118/10892/23291/8517/5588/4790/6885/7334/7316/3551/10454/7321/7335/5970/4792/695/84433/997/8915/7189/7314/6233/257397/4214 32 Foot.and.mouth_disease_virus R-HSA-109581 Apoptosis 36/338 178/10654 1.955445973735716e-19 2.630963673753509e-18 1.4969921330034191e-18 23643/6093/355/7311/7161/329/596/841/7099/5588/8772/331/929/10000/7186/353376/8717/51765/7316/1499/1029/8743/8737/7157/8795/356/207/8626/5366/208/7314/6233/8797/148022/3146/5580 36 Foot.and.mouth_disease_virus R-HSA-918233 TRAF3-dependent IRF activation pathway 13/338 14/10654 3.5775476180248574e-19 4.741585499710557e-18 2.6979149358239302e-18 3665/84282/1387/7187/7706/9641/80143/64135/3456/3661/29110/57506/23586 13 Foot.and.mouth_disease_virus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 14/338 17/10654 5.00954224723187e-19 6.541872816973383e-18 3.722260493299223e-18 1147/11035/81030/8517/4615/7098/4790/3551/8737/5970/4792/4793/4791/148022 14 Foot.and.mouth_disease_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 12/338 12/10654 8.585348890436208e-19 1.0891128306724789e-17 6.196943560014106e-18 3665/7311/7187/9641/7098/7316/3661/29110/7314/6233/10010/148022 12 Foot.and.mouth_disease_virus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12/338 12/10654 8.585348890436208e-19 1.0891128306724789e-17 6.196943560014106e-18 1147/84282/843/841/7706/8517/8772/64135/3551/8737/57506/23586 12 Foot.and.mouth_disease_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 25/338 80/10654 1.0608331237874143e-18 1.3267884703143997e-17 7.549294283438976e-18 6041/7311/4939/9636/5610/11274/8638/7706/4940/7334/7316/4938/3661/2316/4734/9246/3434/5495/6772/51191/7314/4600/4599/6233/23586 25 Foot.and.mouth_disease_virus R-HSA-1257604 PIP3 activates AKT signaling 42/338 264/10654 2.0718100543798077e-18 2.5552324004017628e-17 1.4539017925472335e-17 2475/10014/7249/51135/8660/1147/2308/7311/1460/5170/3725/4615/331/3667/10000/23512/2309/7316/5728/5468/7874/3630/2146/3066/7157/1457/57521/23028/1026/207/4734/5987/3654/7189/6714/208/4303/7314/6233/253260/4193/5515 42 Foot.and.mouth_disease_virus R-HSA-9006925 Intracellular signaling by second messengers 45/338 305/10654 2.3941038367429875e-18 2.912279735654484e-17 1.6570581710694073e-17 2475/10014/7249/51135/8660/1147/2308/7311/1460/5170/3725/5581/4615/331/3667/10000/23512/2309/7316/5728/5468/7874/3630/2146/3066/7157/1457/57521/23028/1026/207/4734/5987/3654/7189/5578/6714/208/4303/7314/6233/253260/4193/5515/5580 45 Foot.and.mouth_disease_virus R-HSA-202403 TCR signaling 29/338 119/10654 3.3930585810700284e-18 4.0716702972840343e-17 2.3167398562071317e-17 7322/8454/6500/1147/7311/5170/8945/23118/10892/23291/8517/5588/4790/6885/7334/7316/5728/3551/7321/7335/5970/4792/8767/84433/997/8915/7189/7314/6233 29 Foot.and.mouth_disease_virus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 11/338 11/10654 2.794307897275631e-17 3.308460550374347e-16 1.8824811097435831e-16 7311/23118/7098/6885/7316/10454/7189/7314/6233/148022/257397 11 Foot.and.mouth_disease_virus R-HSA-933541 TRAF6 mediated IRF7 activation 16/338 29/10654 3.461272884332126e-17 4.044224106956484e-16 2.3011232472014137e-16 3665/84282/1387/7706/9641/7186/80143/64135/3440/3456/3661/29110/7189/57506/10010/23586 16 Foot.and.mouth_disease_virus R-HSA-1169091 Activation of NF-kappaB in B cells 22/338 67/10654 4.039308344918291e-17 4.658319234139535e-16 2.650537259823349e-16 8454/6500/1147/7311/8945/10892/23291/8517/4794/4790/6885/5579/5966/7316/3551/5970/4792/84433/4793/8915/7314/6233 22 Foot.and.mouth_disease_virus R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 15/338 27/10654 3.0070529989329154e-16 3.42341418340055e-15 1.9478885823047227e-15 23643/355/841/7099/8772/929/7186/353376/8717/8743/8737/8795/356/8797/148022 15 Foot.and.mouth_disease_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 23/338 83/10654 5.272804931154001e-16 5.926899720081966e-15 3.3723469246554573e-15 8454/6500/1147/7311/8945/10892/23291/8517/4794/4790/6885/5579/5966/7316/3551/5970/4792/84433/5478/4793/8915/7314/6233 23 Foot.and.mouth_disease_virus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 10/338 10/10654 9.067869895915156e-16 1.0065335584465822e-14 5.727075723735889e-15 7311/23118/6885/3656/7316/10454/7189/7314/6233/257397 10 Foot.and.mouth_disease_virus R-HSA-983169 Class I MHC mediated antigen processing & presentation 46/338 371/10654 9.873090714818778e-16 1.082383278365318e-14 6.158653077469804e-15 7322/8454/6500/23643/1147/8773/7311/23327/8945/6502/6737/23291/10333/7099/8517/4615/10616/929/8452/114609/9903/7323/7334/7316/55294/7097/55008/3551/151636/7321/7428/22954/7335/7096/83737/695/997/4734/63891/10075/9246/9817/51191/7314/6233/3093 46 Foot.and.mouth_disease_virus R-HSA-6804757 Regulation of TP53 Degradation 16/338 36/10654 3.0447141076638363e-15 3.2972025946408373e-14 1.8760754450303486e-14 2475/7311/5170/9099/10000/7316/1029/7874/7157/207/208/7314/6233/253260/4193/5515 16 Foot.and.mouth_disease_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 16/338 37/10654 5.211720937888733e-15 5.575913485355656e-14 3.172639251980459e-14 2475/7311/5170/9099/10000/7316/1029/7874/7157/207/208/7314/6233/253260/4193/5515 16 Foot.and.mouth_disease_virus R-HSA-3371378 Regulation by c-FLIP 10/338 11/10654 9.695226095779123e-15 9.895816980519381e-14 5.6306213260423213e-14 355/841/8772/7186/8717/8743/8737/8795/356/8797 10 Foot.and.mouth_disease_virus R-HSA-5218900 CASP8 activity is inhibited 10/338 11/10654 9.695226095779123e-15 9.895816980519381e-14 5.6306213260423213e-14 355/841/8772/7186/8717/8743/8737/8795/356/8797 10 Foot.and.mouth_disease_virus R-HSA-5603041 IRAK4 deficiency (TLR2/4) 10/338 11/10654 9.695226095779123e-15 9.895816980519381e-14 5.6306213260423213e-14 23643/51135/10333/7099/4615/929/114609/7097/7096/695 10 Foot.and.mouth_disease_virus R-HSA-69416 Dimerization of procaspase-8 10/338 11/10654 9.695226095779123e-15 9.895816980519381e-14 5.6306213260423213e-14 355/841/8772/7186/8717/8743/8737/8795/356/8797 10 Foot.and.mouth_disease_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 24/338 112/10654 6.52941277869212e-14 6.588771076680231e-13 3.7489451360911694e-13 8454/6500/1147/7311/8945/10892/23291/8517/4794/4790/6885/5579/5966/7316/3551/5970/4792/695/84433/5478/4793/8915/7314/6233 24 Foot.and.mouth_disease_virus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 13/338 25/10654 9.684905868833817e-14 9.663142035420707e-13 5.498231599101399e-13 2475/7249/1147/2308/5170/10000/2309/1026/207/208/4303/253260/4193 13 Foot.and.mouth_disease_virus R-HSA-3700989 Transcriptional Regulation by TP53 42/338 365/10654 2.630817464607642e-13 2.5957398984128734e-12 1.4769501555692027e-12 2475/7249/672/355/7311/1460/5170/7161/1432/3725/1387/27165/9099/843/10000/1874/10128/7316/5728/3276/1029/7874/3066/7157/10397/8795/1457/57521/7248/1026/207/8626/5366/6790/22974/208/7314/6233/253260/8797/4193/5515 42 Foot.and.mouth_disease_virus R-HSA-2562578 TRIF-mediated programmed cell death 9/338 10/10654 2.8523549776849994e-13 2.7531426306350864e-12 1.5665107428933636e-12 23643/11035/841/7099/8772/929/353376/8737/148022 9 Foot.and.mouth_disease_virus R-HSA-5602498 MyD88 deficiency (TLR2/4) 9/338 10/10654 2.8523549776849994e-13 2.7531426306350864e-12 1.5665107428933636e-12 23643/10333/7099/4615/929/114609/7097/7096/695 9 Foot.and.mouth_disease_virus R-HSA-1169408 ISG15 antiviral mechanism 19/338 72/10654 5.189782613170878e-13 4.955405333866387e-12 2.8195762923848572e-12 7311/9636/5610/11274/7706/7334/7316/3661/4734/9246/3434/5495/6772/51191/7314/4600/4599/6233/23586 19 Foot.and.mouth_disease_virus R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 9/338 11/10654 1.5251667202957473e-12 1.4407957953432167e-11 8.197984610772214e-12 7311/23118/6885/7316/10454/7189/7314/6233/257397 9 Foot.and.mouth_disease_virus R-HSA-6807070 PTEN Regulation 24/338 140/10654 1.0840796823636556e-11 1.0133292188830803e-10 5.7657423549535155e-11 2475/10014/7311/1460/3725/331/10000/23512/7316/5728/5468/7874/2146/3066/7157/1457/57521/23028/207/4734/5987/208/7314/6233 24 Foot.and.mouth_disease_virus R-HSA-5633007 Regulation of TP53 Activity 25/338 160/10654 3.2827303075593915e-11 3.036525534492437e-10 1.7277527934523114e-10 2475/672/7311/1460/5170/7161/1432/9099/10000/7316/1029/7874/3066/7157/1457/207/8626/6790/22974/208/7314/6233/253260/4193/5515 25 Foot.and.mouth_disease_virus R-HSA-69231 Cyclin D associated events in G1 14/338 44/10654 3.890340225327045e-11 3.5251246123371595e-10 2.005760803605781e-10 8454/6500/5925/7311/6502/1874/7316/1029/1026/6714/7314/1870/6233/5515 14 Foot.and.mouth_disease_virus R-HSA-69236 G1 Phase 14/338 44/10654 3.890340225327045e-11 3.5251246123371595e-10 2.005760803605781e-10 8454/6500/5925/7311/6502/1874/7316/1029/1026/6714/7314/1870/6233/5515 14 Foot.and.mouth_disease_virus R-HSA-5663202 Diseases of signal transduction 39/338 377/10654 5.497633391409159e-11 4.93121055714276e-10 2.805809705344388e-10 2475/10014/7249/8454/6500/5037/8660/1147/2308/7311/5170/1387/6469/4140/3667/10000/3320/2309/7316/1499/55294/5728/9734/8315/3066/4296/1026/207/11140/6772/6714/208/4303/4609/7314/6233/253260/4193/5515 39 Foot.and.mouth_disease_virus R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 9/338 15/10654 1.2399055727741646e-10 1.1010361486234583e-9 6.264786051911569e-10 7311/81030/6737/7316/22954/3661/29110/7314/6233 9 Foot.and.mouth_disease_virus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 19/338 102/10654 3.7070678180209003e-10 3.259283388517386e-9 1.8544997943199917e-9 8454/6500/7124/1147/330/7311/7132/8945/329/7187/23291/7186/958/7316/9020/356/4791/7314/6233 19 Foot.and.mouth_disease_virus R-HSA-1236974 ER-Phagosome pathway 17/338 83/10654 6.797282557029727e-10 5.917634226119997e-9 3.367074950850639e-9 23643/1147/8773/7311/10333/7099/8517/4615/929/114609/7316/7097/3551/7096/695/7314/6233 17 Foot.and.mouth_disease_virus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 33/338 309/10654 8.112154879934261e-10 6.993780129496722e-9 3.979391254336684e-9 7322/8454/6500/7311/23327/8945/6502/6737/23291/10616/8452/9903/7323/7334/7316/55294/55008/151636/7321/7428/22954/7335/83737/997/4734/63891/10075/9246/9817/51191/7314/6233/3093 33 Foot.and.mouth_disease_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 13/338 47/10654 1.3926257958065912e-9 1.1890881794963971e-8 6.765793339951051e-9 10014/8454/6500/7311/3091/1387/7316/55294/9734/3066/4609/7314/6233 13 Foot.and.mouth_disease_virus R-HSA-2559583 Cellular Senescence 25/338 195/10654 2.4334442613013422e-9 2.0579985752719923e-8 1.1709806971675632e-8 5925/7311/1432/3725/57634/3576/4790/23512/23043/9448/7316/6195/1029/3456/7321/2146/3569/7157/5970/1026/6667/7314/1870/6233/4193 25 Foot.and.mouth_disease_virus R-HSA-1227986 Signaling by ERBB2 13/338 50/10654 3.2231530706118306e-9 2.7001508742484016e-8 1.53635896116552e-8 7311/5581/10000/3320/7316/207/11140/5578/6714/208/7314/6233/5580 13 Foot.and.mouth_disease_virus R-HSA-69202 Cyclin E associated events during G1/S transition 16/338 83/10654 5.544979227369492e-9 4.60181453635898e-8 2.6183866494218947e-8 8454/6500/5925/7311/6502/4149/10000/1874/7316/993/1026/207/208/4609/7314/6233 16 Foot.and.mouth_disease_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 16/338 85/10654 7.96488820753292e-9 6.54890808174929e-8 3.72626348890429e-8 8454/6500/5925/7311/6502/4149/10000/1874/7316/993/1026/207/208/4609/7314/6233 16 Foot.and.mouth_disease_virus R-HSA-193704 p75 NTR receptor-mediated signalling 17/338 97/10654 8.411644139439954e-9 6.852788986993282e-8 3.899168698146961e-8 7311/4804/4615/4790/7316/5584/4803/3551/3066/5970/4792/8767/3654/7189/8878/7314/6233 17 Foot.and.mouth_disease_virus R-HSA-205043 NRIF signals cell death from the nucleus 8/338 16/10654 9.743757784354186e-9 7.86586992046047e-8 4.4756016617129285e-8 7311/4804/7316/4803/7189/8878/7314/6233 8 Foot.and.mouth_disease_virus R-HSA-5205647 Mitophagy 10/338 29/10654 1.0594228368144238e-8 8.47538269451539e-8 4.822408361032939e-8 7311/1460/9474/7316/1457/9140/6714/8878/7314/6233 10 Foot.and.mouth_disease_virus R-HSA-1236975 Antigen processing-Cross presentation 17/338 99/10654 1.159731641009672e-8 9.195015153719542e-8 5.231872064705287e-8 23643/1147/8773/7311/10333/7099/8517/4615/929/114609/7316/7097/3551/7096/695/7314/6233 17 Foot.and.mouth_disease_virus R-HSA-2219528 PI3K/AKT Signaling in Cancer 17/338 101/10654 1.5857590462611498e-8 1.2461540115751335e-7 7.090492242248273e-8 2475/7249/8660/1147/2308/5170/3667/10000/2309/5728/1026/207/6714/208/4303/253260/4193 17 Foot.and.mouth_disease_virus R-HSA-2262752 Cellular responses to stress 40/338 479/10654 1.7334258587553176e-8 1.350247511030458e-7 7.682773889220246e-8 2475/7322/5925/7311/3091/1432/3725/1387/2034/57634/23411/3576/3320/4790/23512/7323/23043/9448/7316/6195/112399/1029/3456/10935/7321/7428/2146/3569/7157/5970/57521/1026/2288/6667/2289/7314/1870/6233/4193/3326 40 Foot.and.mouth_disease_virus R-HSA-8953897 Cellular responses to external stimuli 40/338 493/10654 3.858866428167596e-8 2.9797159897502824e-7 1.6954287281651682e-7 2475/7322/5925/7311/3091/1432/3725/1387/2034/57634/23411/3576/3320/4790/23512/7323/23043/9448/7316/6195/112399/1029/3456/10935/7321/7428/2146/3569/7157/5970/57521/1026/2288/6667/2289/7314/1870/6233/4193/3326 40 Foot.and.mouth_disease_virus R-HSA-2559585 Oncogene Induced Senescence 10/338 33/10654 4.371451002773182e-8 3.346421112467746e-7 1.904080291589045e-7 5925/7311/7316/1029/7157/6667/7314/1870/6233/4193 10 Foot.and.mouth_disease_virus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 7/338 13/10654 4.428381834804245e-8 3.358656274301428e-7 1.9110419768429178e-7 7311/10000/7316/207/208/7314/6233 7 Foot.and.mouth_disease_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 17/338 108/10654 4.463079283418564e-8 3.358656274301428e-7 1.9110419768429178e-7 7124/2308/3091/7291/596/6657/3576/3320/2309/3569/7157/356/1026/207/6772/4609/4582 17 Foot.and.mouth_disease_virus R-HSA-453279 Mitotic G1-G1/S phases 20/338 149/10654 4.619076096063018e-8 3.446839977566353e-7 1.961217625926801e-7 8454/6500/5925/7311/6502/4149/10000/1874/7316/1029/993/1026/207/6714/208/4609/7314/1870/6233/5515 20 Foot.and.mouth_disease_virus R-HSA-1980143 Signaling by NOTCH1 14/338 73/10654 5.4335135053695334e-8 4.020799993973455e-7 2.2877951601555934e-7 10014/8454/6500/7311/3091/1387/7316/55294/9734/3066/83737/4609/7314/6233 14 Foot.and.mouth_disease_virus R-HSA-4420097 VEGFA-VEGFR2 Pathway 16/338 99/10654 7.642196982082833e-8 5.608488363710377e-7 3.1911740334056195e-7 2475/3315/6093/5170/1432/5590/10000/3320/5579/1499/207/5578/6714/208/253260/5580 16 Foot.and.mouth_disease_virus R-HSA-198323 AKT phosphorylates targets in the cytosol 7/338 14/10654 8.616367374780054e-8 6.271585433446466e-7 3.5684696634119295e-7 7249/1147/10000/1026/207/208/4193 7 Foot.and.mouth_disease_virus R-HSA-9614085 FOXO-mediated transcription 13/338 65/10654 9.7013173167175745e-008 7.00387786767903e-7 3.9851367668159485e-7 2308/9314/1387/23411/10000/2309/3630/3066/356/1026/207/208/4303 13 Foot.and.mouth_disease_virus R-HSA-8951664 Neddylation 25/338 234/10654 9.92187425833773e-8 7.1053422108096e-7 4.0428689677437276e-7 7322/8454/6500/7311/3091/8945/2034/6502/23291/8533/149951/11091/8452/9903/7323/7316/55294/7321/10987/7428/50813/9817/7314/6233/51138 25 Foot.and.mouth_disease_virus R-HSA-8863795 Downregulation of ERBB2 signaling 9/338 29/10654 1.6733141574054074e-7 1.1887223774208014e-6 6.763711962565016e-7 7311/10000/3320/7316/207/11140/208/7314/6233 9 Foot.and.mouth_disease_virus R-HSA-8948751 Regulation of PTEN stability and activity 13/338 69/10654 2.0361963037965602e-7 1.380648607298498e-6 7.855753099849208e-7 7311/1460/331/10000/7316/5728/1457/207/4734/5987/208/7314/6233 13 Foot.and.mouth_disease_virus R-HSA-389357 CD28 dependent PI3K/Akt signaling 8/338 22/10654 2.0483125279576337e-7 1.380648607298498e-6 7.855753099849208e-7 2475/5170/1326/10000/9020/207/208/253260 8 Foot.and.mouth_disease_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 12/338 58/10654 2.0523154973356052e-7 1.380648607298498e-6 7.855753099849208e-7 10014/8454/6500/7311/1387/7316/55294/9734/3066/4609/7314/6233 12 Foot.and.mouth_disease_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 12/338 58/10654 2.0523154973356052e-7 1.380648607298498e-6 7.855753099849208e-7 10014/8454/6500/7311/1387/7316/55294/9734/3066/4609/7314/6233 12 Foot.and.mouth_disease_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 12/338 58/10654 2.0523154973356052e-7 1.380648607298498e-6 7.855753099849208e-7 10014/8454/6500/7311/1387/7316/55294/9734/3066/4609/7314/6233 12 Foot.and.mouth_disease_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 12/338 58/10654 2.0523154973356052e-7 1.380648607298498e-6 7.855753099849208e-7 10014/8454/6500/7311/1387/7316/55294/9734/3066/4609/7314/6233 12 Foot.and.mouth_disease_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 12/338 58/10654 2.0523154973356052e-7 1.380648607298498e-6 7.855753099849208e-7 10014/8454/6500/7311/1387/7316/55294/9734/3066/4609/7314/6233 12 Foot.and.mouth_disease_virus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 9/338 30/10654 2.3242450136822e-7 1.5422927966742225e-6 8.775492441958592e-7 7322/7311/7316/7874/7321/997/7314/6233/3093 9 Foot.and.mouth_disease_virus R-HSA-194138 Signaling by VEGF 16/338 107/10654 2.3273337247111017e-7 1.5422927966742225e-6 8.775492441958592e-7 2475/3315/6093/5170/1432/5590/10000/3320/5579/1499/207/5578/6714/208/253260/5580 16 Foot.and.mouth_disease_virus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 12/338 60/10654 3.041685467611322e-7 2.000753107584336e-6 1.1384085960650562e-6 8454/6500/1147/7311/8945/23291/7316/9020/5970/4791/7314/6233 12 Foot.and.mouth_disease_virus R-HSA-9614399 Regulation of localization of FOXO transcription factors 6/338 11/10654 3.9403489442272673e-7 2.572816075348392e-6 1.4639067285054863e-6 2308/10000/2309/207/208/4303 6 Foot.and.mouth_disease_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 13/338 73/10654 4.0530090631839345e-7 2.627059889129441e-6 1.4947709184235796e-6 7311/23327/23645/5590/7323/1874/7316/7321/5499/6667/4609/7314/6233 13 Foot.and.mouth_disease_virus R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 10/338 42/10654 5.387583262025524e-7 3.4667927077381637e-6 1.9725705307187274e-6 7311/8945/6657/331/7316/1499/207/208/7314/6233 10 Foot.and.mouth_disease_virus R-HSA-389356 CD28 co-stimulation 9/338 33/10654 5.759310961065986e-7 3.679329592393234e-6 2.093501901788469e-6 2475/5170/1326/10000/9020/207/6714/208/253260 9 Foot.and.mouth_disease_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 11/338 53/10654 6.436588959773324e-7 4.082636425913365e-6 2.322979474203906e-6 7161/596/841/331/10000/1029/7157/207/8626/5366/208 11 Foot.and.mouth_disease_virus R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 6/338 12/10654 7.670606462353918e-7 4.830850027354808e-6 2.74870556321753e-6 355/7161/7157/8795/8626/8797 6 Foot.and.mouth_disease_virus R-HSA-69206 G1/S Transition 17/338 131/10654 7.811962489950896e-7 4.885227247236898e-6 2.7796456598787477e-6 8454/6500/5925/7311/6502/4149/10000/1874/7316/993/1026/207/208/4609/7314/6233/5515 17 Foot.and.mouth_disease_virus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 10/338 44/10654 8.585825055869975e-7 5.294592117786485e-6 3.012570195042097e-6 7311/23327/7323/1874/7316/7321/6667/4609/7314/6233 10 Foot.and.mouth_disease_virus R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 10/338 44/10654 8.585825055869975e-7 5.294592117786485e-6 3.012570195042097e-6 355/7161/1387/843/7157/10397/8795/8626/5366/8797 10 Foot.and.mouth_disease_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 36/338 473/10654 9.219266916649889e-7 5.646006222058691e-6 3.2125213212282736e-6 2475/54106/3315/8660/6093/7311/5170/1432/23118/1213/5590/4914/5581/3667/10000/3320/5579/7316/1499/6195/4803/8471/3630/83737/207/4734/11140/5578/6772/6714/208/7314/6233/253260/5515/5580 36 Foot.and.mouth_disease_virus R-HSA-9612973 Autophagy 16/338 119/10654 1.0219999208797086e-6 6.215999518775214e-6 3.5368418314510463e-6 2475/7249/7311/1460/3320/9474/7316/1457/57521/7248/9140/6714/8878/7314/6233/3326 16 Foot.and.mouth_disease_virus R-HSA-8852135 Protein ubiquitination 13/338 79/10654 1.0442729420136552e-6 6.308261037470243e-6 3.5893377169105233e-6 7322/7311/5591/7323/7334/7316/7874/7321/997/8915/7314/6233/3093 13 Foot.and.mouth_disease_virus R-HSA-5686938 Regulation of TLR by endogenous ligand 7/338 19/10654 1.1026016604020234e-6 6.61560996241214e-6 3.764216194829099e-6 23643/10333/7099/929/7097/7096/3146 7 Foot.and.mouth_disease_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 20/338 182/10654 1.2499693942430502e-6 7.449482027435092e-6 4.238681096691375e-6 672/1387/9063/8517/9641/23512/7022/5468/1029/7428/3066/7157/1788/5970/4792/1786/6790/5987/4791/4193 20 Foot.and.mouth_disease_virus R-HSA-8878166 Transcriptional regulation by RUNX2 16/338 121/10654 1.2828553852799186e-6 7.594503880857118e-6 4.321197087258673e-6 8454/6500/5925/7311/7291/6502/10000/7316/55294/1026/207/6772/6714/208/7314/6233 16 Foot.and.mouth_disease_virus R-HSA-1632852 Macroautophagy 14/338 95/10654 1.5972318346945685e-6 9.392992511316403e-6 5.344519209852861e-6 2475/7249/7311/1460/9474/7316/1457/57521/7248/9140/6714/8878/7314/6233 14 Foot.and.mouth_disease_virus R-HSA-622312 Inflammasomes 7/338 20/10654 1.6503732494681045e-6 9.64165424689261e-6 5.486005261389821e-6 29108/596/351/4790/5970/4791/3326 7 Foot.and.mouth_disease_virus R-HSA-400253 Circadian Clock 12/338 70/10654 1.7386261205621678e-6 1.0090849640909837e-5 5.741592967800761e-6 8454/6500/7311/3091/8945/1387/23411/7316/1454/5499/7314/6233 12 Foot.and.mouth_disease_virus R-HSA-8878159 Transcriptional regulation by RUNX3 14/338 96/10654 1.8170592994307262e-6 1.0477588687626525e-5 5.96164363449589e-6 7311/1387/2309/7316/1499/1029/864/7157/1026/6714/4609/7314/6233/4193 14 Foot.and.mouth_disease_virus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 11/338 59/10654 1.993145847697365e-6 1.1418796856485551e-5 6.497181710660341e-6 8454/6500/1147/7311/8945/23291/7316/9020/4791/7314/6233 11 Foot.and.mouth_disease_virus R-HSA-2990846 SUMOylation 20/338 188/10654 2.083800566611021e-6 1.1861633994555045e-5 6.749151632748247e-6 672/1387/9063/8517/9641/23512/7022/5468/1029/7428/3066/7157/1788/5970/4792/1786/6790/5987/4791/4193 20 Foot.and.mouth_disease_virus R-HSA-5218920 VEGFR2 mediated vascular permeability 8/338 29/10654 2.263131521177162e-6 1.2800387202581654e-5 7.283292860643899e-6 2475/5170/10000/3320/1499/207/208/253260 8 Foot.and.mouth_disease_virus R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 6/338 14/10654 2.3618986174321136e-6 1.327446817898555e-5 7.553040215639004e-6 7161/10000/7157/207/8626/208 6 Foot.and.mouth_disease_virus R-HSA-114452 Activation of BH3-only proteins 8/338 30/10654 3.0015704374713213e-6 1.6763487726254927e-5 9.53825759673111e-6 7161/596/10000/7157/207/8626/5366/208 8 Foot.and.mouth_disease_virus R-HSA-5675221 Negative regulation of MAPK pathway 9/338 40/10654 3.355640186547957e-6 1.862380303534116e-5 1.0596758483835655e-5 5037/7311/4140/1843/7316/8315/7314/6233/5515 9 Foot.and.mouth_disease_virus R-HSA-5205685 Pink/Parkin Mediated Mitophagy 7/338 22/10654 3.4369470747639614e-6 1.8956577654598742e-5 1.0786103928647936e-5 7311/9474/7316/9140/8878/7314/6233 7 Foot.and.mouth_disease_virus R-HSA-1234174 Cellular response to hypoxia 12/338 75/10654 3.702296632566814e-6 2.029407043036624e-5 1.1547124000208388e-5 7322/7311/3091/1387/2034/7323/7316/112399/7321/7428/7314/6233 12 Foot.and.mouth_disease_virus R-HSA-844456 The NLRP3 inflammasome 6/338 15/10654 3.8317153968492924e-6 2.0874621303080805e-5 1.1877451666048824e-5 29108/351/4790/5970/4791/3326 6 Foot.and.mouth_disease_virus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 7/338 23/10654 4.806974912745166e-6 2.6028010503156754e-5 1.480967880691707e-5 7311/23327/7323/7316/7321/7314/6233 7 Foot.and.mouth_disease_virus R-HSA-1295596 Spry regulation of FGF signaling 6/338 16/10654 5.96764004373143e-6 3.211675368990006e-5 1.8274113052574712e-5 7311/7316/6714/7314/6233/5515 6 Foot.and.mouth_disease_virus R-HSA-877300 Interferon gamma signaling 13/338 92/10654 6.091830642621374e-6 3.2587624160528795e-5 1.8542033661751805e-5 3665/4939/8638/6737/7706/10379/4940/4938/3661/2633/6772/3659/5580 13 Foot.and.mouth_disease_virus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 11/338 66/10654 6.271821108800062e-6 3.334956374020632e-5 1.8975569695707723e-5 7322/7311/3091/2034/7323/7316/112399/7321/7428/7314/6233 11 Foot.and.mouth_disease_virus R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 5/338 10/10654 6.897086616850594e-6 3.6456029260495995e-5 2.0743117644663445e-5 2308/1387/23411/2309/4303 5 Foot.and.mouth_disease_virus R-HSA-2559580 Oxidative Stress Induced Senescence 15/338 125/10654 9.324209025959516e-6 4.8993477012142314e-5 2.78768005758989e-5 7311/1432/3725/23512/23043/9448/7316/1029/3456/2146/7157/7314/1870/6233/4193 15 Foot.and.mouth_disease_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 7/338 26/10654 1.188020449127013e-5 6.205659757792869e-5 3.53095861040846e-5 7311/23327/23645/7316/5499/7314/6233 7 Foot.and.mouth_disease_virus R-HSA-4755510 SUMOylation of immune response proteins 5/338 11/10654 1.2316296385540492e-5 6.358646040906952e-5 3.618006282166117e-5 8517/9641/5970/4792/4791 5 Foot.and.mouth_disease_virus R-HSA-8934903 Receptor Mediated Mitophagy 5/338 11/10654 1.2316296385540492e-5 6.358646040906952e-5 3.618006282166117e-5 1460/9474/1457/9140/6714 5 Foot.and.mouth_disease_virus R-HSA-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 6/338 18/10654 1.3108334229573072e-5 6.728439766393576e-5 3.828415229811424e-5 330/329/7187/7186/958/9020 6 Foot.and.mouth_disease_virus R-HSA-69242 S Phase 17/338 161/10654 1.3509395949618972e-5 6.894450346702097e-5 3.922873596985546e-5 8454/6500/5925/7311/6502/4149/10000/1874/7316/993/7321/1026/207/208/4609/7314/6233 17 Foot.and.mouth_disease_virus R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 10/338 59/10654 1.4240648307728071e-5 7.226111827007157e-5 4.1115856768177294e-5 7322/7311/5591/7323/7334/7316/7321/8915/7314/6233 10 Foot.and.mouth_disease_virus R-HSA-5628897 TP53 Regulates Metabolic Genes 12/338 86/10654 1.5844270685851432e-5 7.994154755134132e-5 4.548594455268354e-5 2475/7249/27165/10000/10128/5728/7157/57521/7248/207/8626/208 12 Foot.and.mouth_disease_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 6/338 19/10654 1.8649441569190498e-5 9.251790007509029e-5 5.264176391185792e-5 7311/3320/7316/11140/7314/6233 6 Foot.and.mouth_disease_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 6/338 19/10654 1.8649441569190498e-5 9.251790007509029e-5 5.264176391185792e-5 7311/3320/7316/11140/7314/6233 6 Foot.and.mouth_disease_virus R-HSA-6804760 Regulation of TP53 Activity through Methylation 6/338 19/10654 1.8649441569190498e-5 9.251790007509029e-5 5.264176391185792e-5 7311/7316/7157/7314/6233/4193 6 Foot.and.mouth_disease_virus R-HSA-9006936 Signaling by TGF-beta family members 13/338 102/10654 1.9179719757239294e-5 9.461995080238052e-5 5.383780984488223e-5 7311/23327/23645/5590/7323/1874/7316/7321/5499/6667/4609/7314/6233 13 Foot.and.mouth_disease_virus R-HSA-8943724 Regulation of PTEN gene transcription 10/338 61/10654 1.9320408793385896e-5 9.478741993661147e-5 5.393309811471492e-5 2475/10014/3725/23512/5468/2146/3066/7157/57521/23028 10 Foot.and.mouth_disease_virus R-HSA-5696394 DNA Damage Recognition in GG-NER 8/338 38/10654 2.008979478170998e-5 9.755779645160577e-5 5.550941476620528e-5 7311/8533/7316/10987/50813/7314/6233/51138 8 Foot.and.mouth_disease_virus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 12/338 88/10654 2.0104816160634972e-5 9.755779645160577e-5 5.550941476620528e-5 8454/6500/7311/8945/5347/23291/3320/7316/1454/6790/7314/6233 12 Foot.and.mouth_disease_virus R-HSA-5683057 MAPK family signaling cascades 24/338 294/10654 2.1026334123663553e-5 1.0147491685768062e-4 5.7738217273217994e-5 3315/5037/8660/2308/7311/3725/1438/4140/1437/3667/1843/8452/2309/7316/8315/4296/8202/3569/1439/6714/4609/7314/6233/5515 24 Foot.and.mouth_disease_virus R-HSA-8876384 Listeria monocytogenes entry into host cells 6/338 20/10654 2.593475656335723e-5 1.244868315041147e-4 7.08317675699088e-5 7311/7316/1499/6714/7314/6233 6 Foot.and.mouth_disease_virus R-HSA-8939211 ESR-mediated signaling 20/338 223/10654 2.72962099021801e-5 1.3031738921040823e-4 7.414929684802744e-5 3315/5170/3725/1387/596/5590/10000/3320/2309/3276/8202/23028/207/2288/6667/2289/6714/208/4609/3326 20 Foot.and.mouth_disease_virus R-HSA-9009391 Extra-nuclear estrogen signaling 11/338 77/10654 2.857318934560567e-5 1.3568444994063015e-4 7.720310096195172e-5 3315/5170/596/5590/10000/3320/2309/3276/207/6714/208 11 Foot.and.mouth_disease_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 12/338 92/10654 3.170177270407491e-5 1.497402880915879e-4 8.520073291128755e-5 672/7311/1460/1432/7316/7157/1457/6790/22974/7314/6233/4193 12 Foot.and.mouth_disease_virus R-HSA-5218921 VEGFR2 mediated cell proliferation 6/338 21/10654 3.5345240554317725e-5 1.6606652704885788e-4 9.449020031229468e-5 5170/5590/5579/5578/6714/5580 6 Foot.and.mouth_disease_virus R-HSA-199418 Negative regulation of the PI3K/AKT network 13/338 110/10654 4.3280230856307844e-5 2.012190837717349e-4 1.1449165506215358e-4 51135/8660/4615/3667/10000/5728/3630/207/3654/7189/6714/208/5515 13 Foot.and.mouth_disease_virus R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 13/338 110/10654 4.3280230856307844e-5 2.012190837717349e-4 1.1449165506215358e-4 7311/3725/3576/4790/7316/6195/1029/7321/3569/5970/1026/7314/6233 13 Foot.and.mouth_disease_virus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 9/338 54/10654 4.41204681360701e-5 2.0405716512932422e-4 1.1610649509492132e-4 7311/8533/7316/7874/10987/50813/7314/6233/51138 9 Foot.and.mouth_disease_virus R-HSA-9613829 Chaperone Mediated Autophagy 6/338 22/10654 4.731085060915041e-5 2.176789395902879e-4 1.2385714912676408e-4 7311/3320/7316/7314/6233/3326 6 Foot.and.mouth_disease_virus R-HSA-69275 G2/M Transition 18/338 196/10654 5.042022061132337e-5 2.3078946341677911e-4 1.3131690663828116e-4 8454/6500/7311/8945/5347/23291/3320/7316/993/7157/1026/1454/6790/22974/7314/6233/5515/3326 18 Foot.and.mouth_disease_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 7/338 32/10654 5.1589805357822095e-5 2.3254693988703564e-4 1.323168932500914e-4 7311/23327/23645/7316/5499/7314/6233 7 Foot.and.mouth_disease_virus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 7/338 32/10654 5.1589805357822095e-5 2.3254693988703564e-4 1.323168932500914e-4 7311/1874/7316/6667/4609/7314/6233 7 Foot.and.mouth_disease_virus R-HSA-5656169 Termination of translesion DNA synthesis 7/338 32/10654 5.1589805357822095e-5 2.3254693988703564e-4 1.323168932500914e-4 7311/9636/7706/7316/9246/7314/6233 7 Foot.and.mouth_disease_virus R-HSA-195721 Signaling by WNT 25/338 331/10654 5.198644518948078e-5 2.3315132994070165e-4 1.3266078517251874e-4 8454/6500/7311/1460/8945/1387/1213/8295/6657/331/8452/6885/5579/7316/1499/864/1457/207/1454/5578/208/4609/7314/6233/5515 25 Foot.and.mouth_disease_virus R-HSA-453274 Mitotic G2-G2/M phases 18/338 198/10654 5.762153888986471e-5 2.560192487615327e-4 1.4567240327825471e-4 8454/6500/7311/8945/5347/23291/3320/7316/993/7157/1026/1454/6790/22974/7314/6233/5515/3326 18 Foot.and.mouth_disease_virus R-HSA-157118 Signaling by NOTCH 20/338 235/10654 5.766199296430916e-5 2.560192487615327e-4 1.4567240327825471e-4 10014/8454/6500/7311/3091/3725/1387/7316/55294/5584/9734/3066/7157/83737/207/4904/6772/4609/7314/6233 20 Foot.and.mouth_disease_virus R-HSA-388841 Costimulation by the CD28 family 10/338 70/10654 6.598983601286597e-5 2.9153718596728847e-4 1.6588175588465917e-4 2475/5170/1326/10000/9020/207/6714/208/253260/5515 10 Foot.and.mouth_disease_virus R-HSA-3371571 HSF1-dependent transactivation 6/338 24/10654 8.088201449879264e-5 3.5310750815193364e-4 2.0091465613196797e-4 2475/1387/3320/57521/2288/3326 6 Foot.and.mouth_disease_virus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 11/338 86/10654 8.111929241328206e-5 3.5310750815193364e-4 2.0091465613196797e-4 8454/6500/7311/8945/6502/5347/7316/7321/6790/7314/6233 11 Foot.and.mouth_disease_virus R-HSA-453276 Regulation of mitotic cell cycle 11/338 86/10654 8.111929241328206e-5 3.5310750815193364e-4 2.0091465613196797e-4 8454/6500/7311/8945/6502/5347/7316/7321/6790/7314/6233 11 Foot.and.mouth_disease_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 10/338 73/10654 9.500414467558206e-5 4.1153014864349694e-4 2.341565568384051e-4 8454/6500/7311/7291/6502/7316/55294/6772/7314/6233 10 Foot.and.mouth_disease_virus R-HSA-175474 Assembly Of The HIV Virion 5/338 16/10654 1.0211981874214165e-4 4.338870767608698e-4 2.4687742632197425e-4 7311/7316/5478/7314/6233 5 Foot.and.mouth_disease_virus R-HSA-1834941 STING mediated induction of host immune responses 5/338 16/10654 1.0211981874214165e-4 4.338870767608698e-4 2.4687742632197425e-4 6737/5591/3661/29110/3428 5 Foot.and.mouth_disease_virus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 5/338 16/10654 1.0211981874214165e-4 4.338870767608698e-4 2.4687742632197425e-4 7311/5590/7316/7314/6233 5 Foot.and.mouth_disease_virus R-HSA-9614657 FOXO-mediated transcription of cell death genes 5/338 16/10654 1.0211981874214165e-4 4.338870767608698e-4 2.4687742632197425e-4 2308/1387/2309/356/4303 5 Foot.and.mouth_disease_virus R-HSA-1643713 Signaling by EGFR in Cancer 6/338 25/10654 1.0360599439778493e-4 4.366439620916216e-4 2.484460666239668e-4 7311/3320/7316/11140/7314/6233 6 Foot.and.mouth_disease_virus R-HSA-5610780 Degradation of GLI1 by the proteasome 9/338 60/10654 1.037521126141128e-4 4.366439620916216e-4 2.484460666239668e-4 8454/6500/7311/8945/2735/7316/83737/7314/6233 9 Foot.and.mouth_disease_virus R-HSA-912694 Regulation of IFNA signaling 6/338 26/10654 1.3112373136973913e-4 5.492352521524923e-4 3.125093895604508e-4 11274/3440/3456/6773/3454/6772 6 Foot.and.mouth_disease_virus R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 5/338 17/10654 1.4092912662767474e-4 5.875355138280524e-4 3.343018570856629e-4 2308/9314/2309/1026/4303 5 Foot.and.mouth_disease_virus R-HSA-201681 TCF dependent signaling in response to WNT 19/338 233/10654 1.5519837720036984e-4 6.440007427753664e-4 3.664300101140066e-4 7311/1460/8945/1387/8295/6657/331/8452/7316/1499/864/1457/207/1454/208/4609/7314/6233/5515 19 Foot.and.mouth_disease_virus R-HSA-111465 Apoptotic cleavage of cellular proteins 7/338 38/10654 1.6423217200395605e-4 6.783170639047115e-4 3.8595565513781596e-4 6093/329/841/5588/51765/1499/5580 7 Foot.and.mouth_disease_virus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 7/338 39/10654 1.94780196354334e-4 8.007630294567064e-4 0.00045562619030253577 7311/9636/7706/7316/9246/7314/6233 7 Foot.and.mouth_disease_virus R-HSA-75153 Apoptotic execution phase 8/338 52/10654 2.099866595937623e-4 8.593002475541978e-4 4.889332845258595e-4 6093/329/841/5588/51765/1499/3146/5580 8 Foot.and.mouth_disease_virus R-HSA-162588 Budding and maturation of HIV virion 6/338 29/10654 2.4964919330018674e-4 0.001012276181052812 5.759750674553696e-4 7311/23327/7316/5478/7314/6233 6 Foot.and.mouth_disease_virus R-HSA-5654732 Negative regulation of FGFR3 signaling 6/338 29/10654 2.4964919330018674e-4 0.001012276181052812 5.759750674553696e-4 7311/7316/6714/7314/6233/5515 6 Foot.and.mouth_disease_virus R-HSA-8848021 Signaling by PTK6 8/338 54/10654 2.747659247449032e-4 0.0010958134002943458 6.235069133964985e-4 7311/3091/2034/7316/207/55620/7314/6233 8 Foot.and.mouth_disease_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 8/338 54/10654 2.747659247449032e-4 0.0010958134002943458 6.235069133964985e-4 7311/3091/2034/7316/207/55620/7314/6233 8 Foot.and.mouth_disease_virus R-HSA-9604323 Negative regulation of NOTCH4 signaling 8/338 54/10654 2.747659247449032e-4 0.0010958134002943458 6.235069133964985e-4 8454/6500/7311/7316/55294/207/7314/6233 8 Foot.and.mouth_disease_virus R-HSA-193692 Regulated proteolysis of p75NTR 4/338 11/10654 2.7518737417301704e-4 0.0010958134002943458 6.235069133964985e-4 4804/4790/5970/7189 4 Foot.and.mouth_disease_virus R-HSA-69615 G1/S DNA Damage Checkpoints 9/338 68/10654 2.7682690661182493e-4 0.0010974209512111632 6.244215938612593e-4 7311/7316/1029/993/7157/1026/7314/6233/4193 9 Foot.and.mouth_disease_virus R-HSA-8941858 Regulation of RUNX3 expression and activity 8/338 55/10654 3.1280251791026116e-4 0.0012345272706858308 7.024337244300601e-4 7311/7316/1029/864/6714/7314/6233/4193 8 Foot.and.mouth_disease_virus R-HSA-186712 Regulation of beta-cell development 7/338 42/10654 3.1486536198159433e-4 0.0012371700948657334 7.039374650729637e-4 2308/1387/3642/10000/3630/207/208 7 Foot.and.mouth_disease_virus R-HSA-9607240 FLT3 Signaling 20/338 267/10654 3.2595595217613905e-4 0.0012658790182878824 7.202725566360641e-4 54106/5037/8660/7311/5170/1438/4140/1437/3667/1843/8452/7316/8315/4296/1439/6714/208/7314/6233/5515 20 Foot.and.mouth_disease_virus R-HSA-3232118 SUMOylation of transcription factors 5/338 20/10654 3.2644853061703275e-4 0.0012658790182878824 7.202725566360641e-4 9063/7022/1029/7157/4193 5 Foot.and.mouth_disease_virus R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 5/338 20/10654 3.2644853061703275e-4 0.0012658790182878824 7.202725566360641e-4 7161/1387/7157/8626/5366 5 Foot.and.mouth_disease_virus R-HSA-5654733 Negative regulation of FGFR4 signaling 6/338 31/10654 3.6679883490140864e-4 0.0014161624582280472 8.05782337540852e-4 7311/7316/6714/7314/6233/5515 6 Foot.and.mouth_disease_virus R-HSA-5689877 Josephin domain DUBs 4/338 12/10654 4.0249818601700377e-4 0.001540596505099566 8.765840711804076e-4 7311/7316/7314/6233 4 Foot.and.mouth_disease_virus R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 4/338 12/10654 4.0249818601700377e-4 0.001540596505099566 8.765840711804076e-4 7161/843/7157/8626 4 Foot.and.mouth_disease_virus R-HSA-210745 Regulation of gene expression in beta cells 5/338 21/10654 4.1741830876163244e-4 0.001584048966582605 9.013080890939431e-4 2308/10000/3630/207/208 5 Foot.and.mouth_disease_virus R-HSA-389513 CTLA4 inhibitory signaling 5/338 21/10654 4.1741830876163244e-4 0.001584048966582605 9.013080890939431e-4 10000/207/6714/208/5515 5 Foot.and.mouth_disease_virus R-HSA-1236394 Signaling by ERBB4 8/338 58/10654 4.534277613362408e-4 0.0017133780939003482 9.748950747654898e-4 7311/23118/7316/83737/4734/6714/7314/6233 8 Foot.and.mouth_disease_virus R-HSA-5687128 MAPK6/MAPK4 signaling 10/338 89/10654 4.96640544727032e-4 0.0018687152699898494 0.0010632803812175532 3315/2308/7311/3725/2309/7316/8202/4609/7314/6233 10 Foot.and.mouth_disease_virus R-HSA-5654726 Negative regulation of FGFR1 signaling 6/338 33/10654 5.230557952715443e-4 0.001955359070455981 0.001112579840942237 7311/7316/6714/7314/6233/5515 6 Foot.and.mouth_disease_virus R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 5/338 22/10654 5.262734435123643e-4 0.001955359070455981 0.001112579840942237 3725/351/2309/993/356 5 Foot.and.mouth_disease_virus R-HSA-8863678 Neurodegenerative Diseases 5/338 22/10654 5.262734435123643e-4 0.001955359070455981 0.001112579840942237 3725/351/2309/993/356 5 Foot.and.mouth_disease_virus R-HSA-1679131 Trafficking and processing of endosomal TLR 4/338 13/10654 5.669183887969082e-4 0.002088894312247529 0.0011885600638677264 54106/7098/51284/51311 4 Foot.and.mouth_disease_virus R-HSA-3270619 IRF3-mediated induction of type I IFN 4/338 13/10654 5.669183887969082e-4 0.002088894312247529 0.0011885600638677264 5591/3661/29110/3428 4 Foot.and.mouth_disease_virus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 8/338 60/10654 5.728794571648721e-4 0.0021021361899272997 0.0011960945604138262 8454/6500/7311/6502/7316/1026/7314/6233 8 Foot.and.mouth_disease_virus R-HSA-5654727 Negative regulation of FGFR2 signaling 6/338 34/10654 6.184090476916179e-4 0.0022598651619348013 0.0012858407749273407 7311/7316/6714/7314/6233/5515 6 Foot.and.mouth_disease_virus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 5/338 23/10654 6.551515615707972e-4 0.002384322076536344 0.0013566555200775785 7311/7316/7321/7314/6233 5 Foot.and.mouth_disease_virus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 9/338 77/10654 7.058833115427303e-4 0.002558466859795692 0.0014557421677358134 7311/5347/3320/7316/7157/1026/7314/6233/3326 9 Foot.and.mouth_disease_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 7/338 48/10654 7.301331912624318e-4 0.0026249322827572447 0.0014935603315830697 7311/1438/1437/7316/1439/7314/6233 7 Foot.and.mouth_disease_virus R-HSA-73893 DNA Damage Bypass 7/338 48/10654 7.301331912624318e-4 0.0026249322827572447 0.0014935603315830697 7311/9636/7706/7316/9246/7314/6233 7 Foot.and.mouth_disease_virus R-HSA-174490 Membrane binding and targetting of GAG proteins 4/338 14/10654 7.739555788230555e-4 0.00273813766531822 0.0015579730670373941 7311/7316/7314/6233 4 Foot.and.mouth_disease_virus R-HSA-174495 Synthesis And Processing Of GAG, GAGPOL Polyproteins 4/338 14/10654 7.739555788230555e-4 0.00273813766531822 0.0015579730670373941 7311/7316/7314/6233 4 Foot.and.mouth_disease_virus R-HSA-3371568 Attenuation phase 4/338 14/10654 7.739555788230555e-4 0.00273813766531822 0.0015579730670373941 1387/3320/2288/3326 4 Foot.and.mouth_disease_virus R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 4/338 14/10654 7.739555788230555e-4 0.00273813766531822 0.0015579730670373941 7161/7157/10397/8626 4 Foot.and.mouth_disease_virus R-HSA-9033241 Peroxisomal protein import 8/338 63/10654 7.985745157496095e-4 0.0028140244840700523 0.0016011519112774128 7322/7311/3416/7323/7316/7321/7314/6233 8 Foot.and.mouth_disease_virus R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 5/338 24/10654 8.062751265897473e-4 0.0028187886315421086 0.0016038626637508444 1432/5590/5579/5578/5580 5 Foot.and.mouth_disease_virus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 5/338 24/10654 8.062751265897473e-4 0.0028187886315421086 0.0016038626637508444 596/10000/2309/207/208 5 Foot.and.mouth_disease_virus R-HSA-9012852 Signaling by NOTCH3 7/338 49/10654 8.290400432976275e-4 0.002887010033130562 0.0016426799619519553 7311/1387/7316/4904/6772/7314/6233 7 Foot.and.mouth_disease_virus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 9/338 79/10654 8.51997797433101e-4 0.0029553673598460687 0.0016815746001969097 7311/8533/7316/7874/10987/50813/7314/6233/51138 9 Foot.and.mouth_disease_virus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 9/338 80/10654 9.337733294100956e-4 0.003213917505876608 0.0018286870588202608 8454/6500/7311/8945/5347/7316/7321/7314/6233 9 Foot.and.mouth_disease_virus R-HSA-187037 Signaling by NTRK1 (TRKA) 9/338 80/10654 9.337733294100956e-4 0.003213917505876608 0.0018286870588202608 8660/1432/1213/4914/3667/6195/4803/6714/5515 9 Foot.and.mouth_disease_virus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 5/338 25/10654 9.81942409637734e-4 0.0033537109990704147 0.0019082281644781877 7311/7316/7321/7314/6233 5 Foot.and.mouth_disease_virus R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus 5/338 25/10654 9.81942409637734e-4 0.0033537109990704147 0.0019082281644781877 7311/7316/4904/7314/6233 5 Foot.and.mouth_disease_virus R-HSA-111447 Activation of BAD and translocation to mitochondria 4/338 15/10654 0.001029185875522752 0.0034618070358492566 0.0019697337330578987 596/10000/207/208 4 Foot.and.mouth_disease_virus R-HSA-2691230 Signaling by NOTCH1 HD Domain Mutants in Cancer 4/338 15/10654 0.001029185875522752 0.0034618070358492566 0.0019697337330578987 7311/7316/7314/6233 4 Foot.and.mouth_disease_virus R-HSA-2691232 Constitutive Signaling by NOTCH1 HD Domain Mutants 4/338 15/10654 0.001029185875522752 0.0034618070358492566 0.0019697337330578987 7311/7316/7314/6233 4 Foot.and.mouth_disease_virus R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 4/338 15/10654 0.001029185875522752 0.0034618070358492566 0.0019697337330578987 7311/7316/7314/6233 4 Foot.and.mouth_disease_virus R-HSA-69563 p53-Dependent G1 DNA Damage Response 8/338 66/10654 0.0010907523624341911 0.0036413086385021116 0.0020718683576114436 7311/7316/1029/7157/1026/7314/6233/4193 8 Foot.and.mouth_disease_virus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 8/338 66/10654 0.0010907523624341911 0.0036413086385021116 0.0020718683576114436 7311/7316/1029/7157/1026/7314/6233/4193 8 Foot.and.mouth_disease_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 9/338 82/10654 0.0011164506339901646 0.0036992841902360675 0.0021048558692666106 8454/6500/7311/8945/7316/1499/7314/6233/5515 9 Foot.and.mouth_disease_virus R-HSA-9013694 Signaling by NOTCH4 9/338 82/10654 0.0011164506339901646 0.0036992841902360675 0.0021048558692666106 8454/6500/7311/1387/7316/55294/207/7314/6233 9 Foot.and.mouth_disease_virus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 6/338 38/10654 0.0011410328542437514 0.00376668094635112 0.0021432039524046202 1387/7022/1026/10765/8089/4609 6 Foot.and.mouth_disease_virus R-HSA-5684996 MAPK1/MAPK3 signaling 18/338 255/10654 0.0012755859996547222 0.0041952606210866415 0.0023870615198217024 5037/8660/7311/1438/4140/1437/3667/1843/8452/7316/8315/4296/3569/1439/6714/7314/6233/5515 18 Foot.and.mouth_disease_virus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 9/338 84/10654 0.0013270106348543323 0.004336965730917025 0.002467690316311252 7311/8533/7334/7316/10987/50813/7314/6233/51138 9 Foot.and.mouth_disease_virus R-HSA-110312 Translesion synthesis by REV1 4/338 16/10654 0.0013382078944496226 0.004336965730917025 0.002467690316311252 7311/7316/7314/6233 4 Foot.and.mouth_disease_virus R-HSA-3229121 Glycogen storage diseases 4/338 16/10654 0.0013382078944496226 0.004336965730917025 0.002467690316311252 7311/7316/7314/6233 4 Foot.and.mouth_disease_virus R-HSA-3322077 Glycogen synthesis 4/338 16/10654 0.0013382078944496226 0.004336965730917025 0.002467690316311252 7311/7316/7314/6233 4 Foot.and.mouth_disease_virus R-HSA-9006931 Signaling by Nuclear Receptors 20/338 299/10654 0.001351197556212053 0.004363139745150193 0.0024825830697867385 3315/5170/3725/1387/596/5590/10000/3320/2309/3276/8202/23028/207/2288/6667/2289/6714/208/4609/3326 20 Foot.and.mouth_disease_virus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 7/338 54/10654 0.0014928562194663599 0.004803102619152636 0.002732917564240476 8454/6500/7311/7316/6790/7314/6233 7 Foot.and.mouth_disease_virus R-HSA-165159 mTOR signalling 6/338 40/10654 0.0015042532863942363 0.004804952943590223 0.0027339703804211794 2475/7249/57521/7248/207/208 6 Foot.and.mouth_disease_virus R-HSA-5654741 Signaling by FGFR3 6/338 40/10654 0.0015042532863942363 0.004804952943590223 0.0027339703804211794 7311/7316/6714/7314/6233/5515 6 Foot.and.mouth_disease_virus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 10/338 103/10654 0.0015589407597706643 0.0049617899450765226 0.0028232090725897716 51135/8660/4615/3667/3630/207/3654/7189/6714/5515 10 Fowl_adenovirus_A R-HSA-3247509 Chromatin modifying enzymes 102/574 274/10654 3.2012968617762736e-60 1.5702361107012623e-57 1.0025113856615173e-57 55904/9643/64426/23569/57504/5931/79685/8850/23774/6595/9070/84661/5928/5077/10524/1387/58508/27154/6598/79813/1019/57634/1386/57459/8295/10629/51317/10419/8841/5927/6599/6907/8607/9739/84159/8726/54815/11091/23081/4790/7403/9869/79718/64769/2033/51742/79595/23512/7862/6605/6597/3054/6602/55929/8819/595/3276/83933/2648/6601/9611/7994/23186/55869/10284/2874/8242/2146/3066/3065/5978/84289/1788/10856/53615/9112/5970/9682/1107/79084/9219/9612/23028/10362/8085/29072/23135/4297/63976/10765/6839/25855/6871/10919/10933/1108/23067/5926/2122/55170/5929/9757 102 Fowl_adenovirus_A R-HSA-4839726 Chromatin organization 102/574 274/10654 3.2012968617762736e-60 1.5702361107012623e-57 1.0025113856615173e-57 55904/9643/64426/23569/57504/5931/79685/8850/23774/6595/9070/84661/5928/5077/10524/1387/58508/27154/6598/79813/1019/57634/1386/57459/8295/10629/51317/10419/8841/5927/6599/6907/8607/9739/84159/8726/54815/11091/23081/4790/7403/9869/79718/64769/2033/51742/79595/23512/7862/6605/6597/3054/6602/55929/8819/595/3276/83933/2648/6601/9611/7994/23186/55869/10284/2874/8242/2146/3066/3065/5978/84289/1788/10856/53615/9112/5970/9682/1107/79084/9219/9612/23028/10362/8085/29072/23135/4297/63976/10765/6839/25855/6871/10919/10933/1108/23067/5926/2122/55170/5929/9757 102 Fowl_adenovirus_A R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 72/574 182/10654 1.898582387820828e-44 5.3051190482660916e-42 3.3870334607203436e-42 672/1912/115426/80012/7153/10155/23468/5905/367/9972/7341/4928/1387/84733/6613/23636/10521/6670/5903/1616/1789/23225/7155/5914/2908/25942/8021/7181/1487/2033/23512/83746/3622/57332/5468/142/1029/11315/8204/53371/7486/1655/7428/3066/3065/23314/1788/7157/9112/5970/4792/1107/9759/8535/9612/1911/6256/51564/6304/1786/7329/9994/6045/5987/493861/5371/5111/2099/51588/6015/4193/4869 72 Fowl_adenovirus_A R-HSA-2990846 SUMOylation 73/574 188/10654 2.1631474202919842e-44 5.3051190482660916e-42 3.3870334607203436e-42 672/1912/115426/80012/7153/10155/23468/5905/367/9972/7341/4928/1387/84733/6613/23636/10521/6670/5903/1616/1789/23225/7155/5914/2908/25942/8021/7181/29843/1487/2033/23512/83746/3622/57332/5468/142/1029/11315/8204/53371/7486/1655/7428/3066/3065/23314/1788/7157/9112/5970/4792/1107/9759/8535/9612/1911/6256/51564/6304/1786/7329/9994/6045/5987/493861/5371/5111/2099/51588/6015/4193/4869 73 Fowl_adenovirus_A R-HSA-8943724 Regulation of PTEN gene transcription 42/574 61/10654 1.3943986721433886e-39 2.7358101947453284e-37 1.7466678103690866e-37 10014/1912/80012/57504/5931/1958/5928/3725/6591/84733/1386/57459/8841/8726/54815/23512/57332/5468/1822/23186/23466/6615/2146/3066/3065/5978/7157/53615/9112/1107/9219/8535/23028/1911/51564/6045/1108/57167/2122/6015/84232/7101 42 Fowl_adenovirus_A R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 35/574 47/10654 4.150006427813686e-35 6.785260509475377e-33 4.332024253594987e-33 10014/22938/84441/23493/8850/3091/10013/1387/8841/7089/10046/6907/7090/79718/79885/2033/83933/2648/9734/9611/3516/55869/7091/3066/3065/4851/7088/9759/9612/51564/55534/3280/9794/4609/6233 35 Fowl_adenovirus_A R-HSA-8878171 Transcriptional regulation by RUNX1 70/574 239/10654 2.2732919067095503e-33 3.1858562292600984e-31 2.0339980217927554e-31 55904/1912/27327/80012/2811/8850/6688/6595/9070/1460/84661/7161/860/25/1387/84733/58508/894/161882/6598/6599/4773/8861/192670/25942/9739/4343/11091/2033/1021/6605/6597/6602/57332/595/50943/3276/6601/6886/865/23466/26523/7057/192669/3065/1457/8535/861/8085/1911/23429/4297/3674/57678/896/6045/10413/2623/5371/23112/23309/2625/2099/57690/23067/6015/6233/55170/5929/9757 70 Fowl_adenovirus_A R-HSA-6807070 PTEN Regulation 54/574 140/10654 9.284245732239805e-33 1.138480632915906e-30 7.26858711931932e-31 10014/1912/27327/80012/57504/5931/1958/1460/5928/3725/6591/84733/1386/57459/8841/192670/4343/8726/54815/23512/57332/5468/1822/23186/23466/26523/6615/192669/2146/3066/3065/5978/7157/53615/9112/1107/1457/9219/8535/23028/1911/51564/6045/5987/5371/23112/57690/1108/57167/2122/6015/6233/84232/7101 54 Fowl_adenovirus_A R-HSA-350054 Notch-HLH transcription pathway 25/574 28/10654 3.2802648227068644e-29 3.575488656750482e-27 2.2827573912404494e-27 10014/22938/84441/8850/10013/1387/8841/10046/6907/79718/79885/83933/2648/9734/9611/3516/55869/3066/3065/4851/9759/9612/51564/55534/9794 25 Fowl_adenovirus_A R-HSA-212165 Epigenetic regulation of gene expression 51/574 149/10654 4.537919508247682e-28 4.451699037590976e-26 2.8421706393761797e-26 8467/64426/57504/5931/79685/8850/23451/5928/29947/5252/57459/1789/6908/23411/25942/11335/11176/8932/9015/8726/54815/2033/51742/79595/23512/8819/2648/2074/79101/23378/10284/2146/3066/3065/29128/1788/7270/53615/9112/1107/9219/9013/1786/6839/9014/23309/10919/7343/1108/29115/9188 51 Fowl_adenovirus_A R-HSA-5633007 Regulation of TP53 Activity 51/574 160/10654 2.116742248065817e-26 1.887749223047788e-24 1.2052264474633121e-24 672/5931/5519/1017/23774/1460/7161/5928/3364/1432/10524/545/27154/5518/472/79813/57459/1616/6908/10419/8851/5300/54815/64769/2033/7862/5600/639/3622/5883/7994/1029/890/7486/3066/3065/84289/7157/53615/1107/1457/54971/9219/983/5371/10919/1108/6233/4193/6878/29117 51 Fowl_adenovirus_A R-HSA-2559583 Cellular Senescence 56/574 195/10654 2.562305541765805e-26 2.0946847803935456e-24 1.3373436818865384e-24 1912/27327/80012/898/5931/2353/1017/5925/5928/1432/3725/10524/1051/84733/472/79813/1019/57634/5601/192670/4343/8726/5602/4790/5599/23512/1021/5600/57332/1869/1029/7027/23466/26523/890/192669/2146/6774/7157/5970/8535/1026/1911/23135/6045/6667/8091/23112/10919/57690/1870/23523/6015/6233/4193/1871 56 Fowl_adenovirus_A R-HSA-1257604 PIP3 activates AKT signaling 65/574 264/10654 3.246034300927882e-26 2.449507422469425e-24 1.5638788737263885e-24 10014/1912/27327/80012/1385/57504/5931/5519/1958/1460/5928/3725/6591/84733/2931/5518/1386/57459/1956/8841/5290/192670/4343/8726/54815/23512/2100/57332/5468/1822/23186/23466/26523/6615/192669/23239/2146/3066/3065/5978/7157/53615/9112/1107/1457/9219/8535/23028/1026/1911/51564/6045/5987/5371/23112/2099/57690/1108/57167/2122/6015/6233/4193/84232/7101 65 Fowl_adenovirus_A R-HSA-3700989 Transcriptional Regulation by TP53 76/574 365/10654 1.6011549062500508e-25 1.1219521164509284e-23 7.163061422697596e-24 672/27327/898/5931/5519/2353/1017/604/23774/1460/7161/5928/3364/1432/3725/10524/1387/545/27154/5518/472/79813/1386/57459/1616/6908/10419/5325/8851/192670/5300/4343/54815/64769/2033/5934/7862/5600/639/1874/3622/3276/5883/1869/891/7994/1029/7027/26523/890/7486/192669/3066/3065/84289/7157/53615/1107/1457/54971/9219/983/1026/5933/5371/23112/5111/10919/57690/1643/1108/6233/4193/6878/4869/29117 76 Fowl_adenovirus_A R-HSA-1980143 Signaling by NOTCH1 35/574 73/10654 1.7593768314324283e-25 1.1506324477568082e-23 7.346169927735402e-24 10014/22938/84441/23493/8850/3091/10013/1387/8841/7089/10046/6907/7090/79718/79885/2033/83933/2648/9734/9611/3516/55869/7091/3066/3065/4851/7088/9759/9612/51564/55534/3280/9794/4609/6233 35 Fowl_adenovirus_A R-HSA-9006925 Intracellular signaling by second messengers 67/574 305/10654 6.127972262455649e-24 3.7572129934181195e-22 2.3987786158954676e-22 10014/1912/27327/80012/1385/57504/5931/5519/1958/1460/5928/3725/6591/84733/2931/5518/1386/57459/1956/8841/5290/192670/4343/8726/54815/23512/2100/57332/5468/1822/23186/23466/26523/6615/816/192669/23239/2146/3066/3065/5978/7157/53615/9112/1107/1457/9219/8535/23028/1026/1911/51564/6045/5987/5371/23112/2099/57690/1108/57167/2122/6015/6233/4193/84232/7101/5566 67 Fowl_adenovirus_A R-HSA-3899300 SUMOylation of transcription cofactors 27/574 45/10654 2.1319969527345754e-23 1.230287653313305e-21 7.854725615337909e-22 1912/115426/80012/10155/7341/1387/84733/6613/10521/1616/25942/1487/2033/3622/57332/11315/8204/1655/8535/9612/1911/7329/9994/6045/51588/6015/4869 27 Fowl_adenovirus_A R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 30/574 58/10654 2.950270335430484e-23 1.3155523632078659e-21 8.399094974072429e-22 10014/22938/84441/23493/8850/10013/1387/8841/10046/6907/79718/79885/2033/83933/2648/9734/9611/3516/55869/3066/3065/4851/9759/9612/51564/55534/3280/9794/4609/6233 30 Fowl_adenovirus_A R-HSA-2644603 Signaling by NOTCH1 in Cancer 30/574 58/10654 2.950270335430484e-23 1.3155523632078659e-21 8.399094974072429e-22 10014/22938/84441/23493/8850/10013/1387/8841/10046/6907/79718/79885/2033/83933/2648/9734/9611/3516/55869/3066/3065/4851/9759/9612/51564/55534/3280/9794/4609/6233 30 Fowl_adenovirus_A R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 30/574 58/10654 2.950270335430484e-23 1.3155523632078659e-21 8.399094974072429e-22 10014/22938/84441/23493/8850/10013/1387/8841/10046/6907/79718/79885/2033/83933/2648/9734/9611/3516/55869/3066/3065/4851/9759/9612/51564/55534/3280/9794/4609/6233 30 Fowl_adenovirus_A R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 30/574 58/10654 2.950270335430484e-23 1.3155523632078659e-21 8.399094974072429e-22 10014/22938/84441/23493/8850/10013/1387/8841/10046/6907/79718/79885/2033/83933/2648/9734/9611/3516/55869/3066/3065/4851/9759/9612/51564/55534/3280/9794/4609/6233 30 Fowl_adenovirus_A R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 30/574 58/10654 2.950270335430484e-23 1.3155523632078659e-21 8.399094974072429e-22 10014/22938/84441/23493/8850/10013/1387/8841/10046/6907/79718/79885/2033/83933/2648/9734/9611/3516/55869/3066/3065/4851/9759/9612/51564/55534/3280/9794/4609/6233 30 Fowl_adenovirus_A R-HSA-157118 Signaling by NOTCH 57/574 235/10654 1.0115485176051699e-22 4.3144743294377024e-21 2.7545600364992035e-21 10014/27327/22938/1385/84441/23493/8850/3091/5087/3725/51548/10013/1387/1956/4088/8841/7089/10046/192670/6907/4343/7090/79718/79885/2033/595/83933/2648/1869/9734/9611/7027/26523/3516/55869/7091/192669/3066/3065/4851/7157/7088/9759/9612/861/51564/4904/23112/6772/55534/57690/3280/9794/4609/6233/10320/1871 57 Fowl_adenovirus_A R-HSA-6804758 Regulation of TP53 Activity through Acetylation 22/574 30/10654 3.262949203556742e-22 1.3337304869538183e-20 8.515152526825708e-21 5931/23774/5928/27154/57459/5300/54815/64769/2033/7862/3622/7994/3066/3065/84289/7157/53615/1107/9219/5371/1108/29117 22 Fowl_adenovirus_A R-HSA-1538133 G0 and Early G1 21/574 27/10654 3.5137094069076205e-22 1.3787795712705503e-20 8.802766724673827e-21 55957/7153/898/1017/5928/91750/4149/4605/286826/5934/1874/1869/1875/7027/890/3065/983/132660/5933/5111/4609 21 Fowl_adenovirus_A R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 25/574 42/10654 1.2496014267148562e-21 4.714842306181823e-20 3.0101734773090666e-20 7514/90780/9070/26108/283149/51176/8945/6657/607/7089/324/7090/1487/1499/7091/3065/7088/83439/8085/6934/6233/4221/6932/55553/5929 25 Fowl_adenovirus_A R-HSA-2559580 Oxidative Stress Induced Senescence 39/574 125/10654 4.735978700317378e-20 1.7207389277819809e-18 1.0985993476369746e-18 1912/27327/80012/5931/2353/5928/1432/3725/84733/1019/5601/192670/4343/8726/5602/5599/23512/1021/5600/57332/1869/1029/7027/23466/26523/192669/2146/7157/8535/1911/23135/6045/23112/57690/1870/6015/6233/4193/1871 39 Fowl_adenovirus_A R-HSA-8953750 Transcriptional Regulation by E2F6 22/574 35/10654 6.38010000634584e-20 2.2353136093661674e-18 1.4271276329984114e-18 672/80012/5931/23468/5928/79813/4149/11335/8726/23512/83746/1869/7027/23269/2146/1876/1911/23429/6045/10919/6015/84108 22 Fowl_adenovirus_A R-HSA-2262752 Cellular responses to stress 78/574 479/10654 3.2939868912950128e-019 1.1142762552966923e-17 7.114055173577251e-18 1912/27327/80012/898/5931/2353/1017/5925/3091/5928/367/9972/1432/3725/10524/4928/1051/1410/10013/1387/84733/545/472/23636/79813/1019/57634/5903/5601/23225/23411/192670/2908/8021/4343/8726/55662/5602/4790/5599/2033/23512/1021/5600/57332/1869/1029/7027/23466/26523/890/53371/405/816/7428/192669/2146/6774/7157/3297/5970/8535/1026/1911/23135/6045/6667/8091/23112/10919/57690/3308/1870/23523/6015/6233/4193/1871 78 Fowl_adenovirus_A R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 22/574 38/10654 8.249402624407746e-19 2.697554658181333e-17 1.7222437057974066e-17 1912/80012/6595/1460/84733/6598/6599/2033/6605/6597/6602/57332/6601/865/23466/1457/8535/861/1911/23429/6045/6015 22 Fowl_adenovirus_A R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 15/574 16/10654 1.194898050271232e-18 3.781274152632511e-17 2.4141403732135246e-17 55957/5928/91750/4605/286826/5934/1874/1869/1875/7027/890/3065/983/132660/5933 15 Fowl_adenovirus_A R-HSA-8878159 Transcriptional regulation by RUNX3 33/574 96/10654 1.3235835934753948e-18 4.0576109537480074e-17 2.590566572756118e-17 4089/22938/84441/57154/8850/51176/1387/6097/4088/10046/2033/595/1499/2648/1029/865/864/3516/4851/7157/9759/83439/861/1026/10413/55534/6934/3280/9794/4609/6233/4193/6932 33 Fowl_adenovirus_A R-HSA-8953897 Cellular responses to external stimuli 78/574 493/10654 1.9130901708546104e-18 5.687095326085978e-17 3.630904789979244e-17 1912/27327/80012/898/5931/2353/1017/5925/3091/5928/367/9972/1432/3725/10524/4928/1051/1410/10013/1387/84733/545/472/23636/79813/1019/57634/5903/5601/23225/23411/192670/2908/8021/4343/8726/55662/5602/4790/5599/2033/23512/1021/5600/57332/1869/1029/7027/23466/26523/890/53371/405/816/7428/192669/2146/6774/7157/3297/5970/8535/1026/1911/23135/6045/6667/8091/23112/10919/57690/3308/1870/23523/6015/6233/4193/1871 78 Fowl_adenovirus_A R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 16/574 19/10654 3.435791608008737e-18 9.913269316048738e-17 6.329089804226622e-17 55957/7153/5928/91750/4149/286826/5934/1874/1869/1875/7027/3065/132660/5933/5111/4609 16 Fowl_adenovirus_A R-HSA-3214815 HDACs deacetylate histones 32/574 94/10654 6.206733225432325e-18 1.7396586554711746e-16 1.1106785771826264e-16 64426/57504/5931/79685/5928/57459/51317/8841/6907/54815/79718/51742/8819/83933/9611/23186/55869/10284/2874/3066/3065/5978/53615/9112/1107/9219/9612/23028/10362/25855/1108/5926 32 Fowl_adenovirus_A R-HSA-9022692 Regulation of MECP2 expression and activity 20/574 33/10654 9.148390613884386e-18 2.492936442283495e-16 1.5916059693746225e-16 27327/1385/8841/192670/25942/6907/4343/79718/9611/26523/2874/816/192669/3066/3065/9612/4204/23112/57690/5566 20 Fowl_adenovirus_A R-HSA-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function 32/574 97/10654 1.7985224437213997e-17 4.768514911596467e-16 3.0444405519608324e-16 55904/27327/2811/8850/9070/84661/58508/161882/192670/25942/9739/4343/11091/2033/3276/865/26523/7057/192669/3065/861/8085/4297/3674/2623/23112/23309/57690/23067/55170/5929/9757 32 Fowl_adenovirus_A R-HSA-170834 Signaling by TGF-beta Receptor Complex 28/574 73/10654 1.9827565606372477e-17 5.118642594697737e-16 3.2679782647622224e-16 4089/22938/7514/57154/11171/60436/7050/4088/1874/142/1875/9611/7027/5501/3065/6497/6498/9612/9040/4087/5499/6667/5933/4092/4609/6233/4221/5054 28 Fowl_adenovirus_A R-HSA-73762 RNA Polymerase I Transcription Initiation 23/574 47/10654 2.0654055927174e-17 5.195289452450691e-16 3.31691316509272e-16 57504/5931/8850/5928/57459/6908/9015/54815/2648/2074/79101/3066/3065/7270/53615/9112/1107/9219/9013/9014/10919/7343/1108 23 Fowl_adenovirus_A R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 22/574 44/10654 5.749860143086017e-17 1.4101532000918456e-15 9.003070487200473e-16 4089/22938/60436/7050/4088/1874/142/1875/9611/7027/3065/6497/6498/9612/4087/6667/5933/4092/4609/6233/4221/5054 22 Fowl_adenovirus_A R-HSA-9006931 Signaling by Nuclear Receptors 56/574 299/10654 9.348742567197722e-17 2.236857672785601e-15 1.4281134345269945e-15 27327/7514/1385/2353/8850/5915/6257/3725/2354/10524/1387/1386/6908/1956/8841/5914/5467/5290/3169/192670/6907/4343/7090/6258/7764/79718/2033/2100/595/3276/9611/865/5469/26523/1105/8204/5916/2874/1655/192669/3065/2002/9682/9612/861/23028/6256/57678/5451/6667/23112/2625/2099/57690/4609/7528 56 Fowl_adenovirus_A R-HSA-4551638 SUMOylation of chromatin organization proteins 27/574 71/10654 9.709119930055368e-17 2.267773012234361e-15 1.4478512176398355e-15 1912/80012/23468/9972/7341/4928/84733/6613/23636/5903/23225/8021/23512/83746/57332/53371/3066/3065/23314/1107/9759/8535/1911/6304/7329/6045/6015 27 Fowl_adenovirus_A R-HSA-2559585 Oncogene Induced Senescence 19/574 33/10654 2.381648228135945e-16 5.4334811902357265e-15 3.4689857912873614e-15 27327/5925/1019/192670/4343/1021/1869/1029/7027/26523/192669/7157/6667/23112/57690/1870/6233/4193/1871 19 Fowl_adenovirus_A R-HSA-8941856 RUNX3 regulates NOTCH signaling 13/574 14/10654 3.7692142841481646e-16 8.40363457443034e-15 5.365269136526693e-15 22938/84441/8850/1387/10046/2033/2648/864/3516/4851/55534/3280/9794 13 Fowl_adenovirus_A R-HSA-9006936 Signaling by TGF-beta family members 31/574 102/10654 8.023089790797481e-16 1.749033574393851e-14 1.1166639591870177e-14 4089/4093/22938/7514/57154/4086/11171/60436/7050/4088/1874/142/1875/9611/7027/5501/3065/6497/6498/9612/9040/4087/5499/6667/5933/4092/4090/4609/6233/4221/5054 31 Fowl_adenovirus_A R-HSA-8934593 Regulation of RUNX1 Expression and Activity 14/574 17/10654 8.725572401121525e-16 1.860823157717438e-14 1.1880356015256997e-14 27327/894/192670/4343/1021/595/865/26523/192669/861/896/5371/23112/57690 14 Fowl_adenovirus_A R-HSA-201722 Formation of the beta-catenin:TCF transactivating complex 29/574 91/10654 1.7009910666160686e-15 3.550366460319922e-14 2.2667182186709087e-14 90780/79577/9070/26108/283149/51176/10524/1387/8295/607/7089/8607/7015/7090/2033/6597/1499/864/7091/3065/7088/83439/8085/6934/4609/4221/123169/6932/5929 29 Fowl_adenovirus_A R-HSA-453279 Mitotic G1-G1/S phases 37/574 149/10654 1.8067106967433187e-15 3.692464986469158e-14 2.3574404924611286e-14 55957/7153/898/5519/1017/5925/5928/25/894/5518/91750/1019/4149/4605/286826/5934/1021/1874/595/1869/891/1875/1029/7027/890/3065/1876/983/1026/896/132660/5933/5111/4609/1870/6233/1871 37 Fowl_adenovirus_A R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 16/574 25/10654 5.347009721316734e-15 1.0704931707370847e-13 6.834523703938681e-14 22938/84441/23493/8850/5087/1387/10046/2033/2648/3516/4851/6772/55534/3280/9794/10320 16 Fowl_adenovirus_A R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 26/574 77/10654 1.0405696585544064e-14 2.0415976700837456e-13 1.30345041439973e-13 672/1912/80012/9972/7341/4928/84733/6613/23636/5903/23225/8021/57332/142/1029/53371/7486/8535/1911/51564/7329/6045/493861/5371/51588/6015 26 Fowl_adenovirus_A R-HSA-3214841 PKMTs methylate histone lysines 25/574 71/10654 1.1156479699320913e-14 2.1459816833399638e-13 1.3700939981622173e-13 55904/5931/9070/84661/5928/58508/79813/9739/8726/11091/4790/9869/23512/2146/5970/8085/29072/4297/63976/6839/10919/23067/2122/5929/9757 25 Fowl_adenovirus_A R-HSA-9018519 Estrogen-dependent gene expression 36/574 150/10654 1.3804917683863975e-14 2.6043508168981844e-13 1.662738061113171e-13 27327/2353/8850/3725/2354/10524/1387/1386/6908/3169/192670/4343/7090/7764/2033/595/3276/865/5469/26523/1105/8204/1655/192669/3065/861/23028/57678/5451/6667/23112/2625/2099/57690/4609/7528 36 Fowl_adenovirus_A R-HSA-69231 Cyclin D associated events in G1 20/574 44/10654 1.6064809315526977e-14 2.918440358987401e-13 1.8632673572589768e-13 5519/5925/25/894/5518/1019/5934/1021/1874/595/1869/1875/1029/7027/1026/896/5933/1870/6233/1871 20 Fowl_adenovirus_A R-HSA-69236 G1 Phase 20/574 44/10654 1.6064809315526977e-14 2.918440358987401e-13 1.8632673572589768e-13 5519/5925/25/894/5518/1019/5934/1021/1874/595/1869/1875/1029/7027/1026/896/5933/1870/6233/1871 20 Fowl_adenovirus_A R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 14/574 20/10654 4.276427653449863e-14 7.627591869153301e-13 4.869807567086446e-13 22938/84441/23493/8850/1387/4088/10046/2033/2648/3516/4851/55534/3280/9794 14 Fowl_adenovirus_A R-HSA-4655427 SUMOylation of DNA methylation proteins 13/574 17/10654 5.512225699393657e-14 9.656238234116388e-13 6.164989269058695e-13 1912/80012/7341/84733/1789/57332/1788/8535/1911/1786/7329/6045/6015 13 Fowl_adenovirus_A R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 17/574 32/10654 5.725405305016335e-14 9.683832076243147e-13 6.182606454600215e-13 4089/22938/60436/7050/4088/1874/1875/7027/3065/4087/6667/5933/4092/4609/6233/4221/5054 17 Fowl_adenovirus_A R-HSA-8941326 RUNX2 regulates bone development 17/574 32/10654 5.725405305016335e-14 9.683832076243147e-13 6.182606454600215e-13 4089/2736/23493/4086/5925/367/860/10013/25/8841/2737/865/23314/9759/10413/3280/25925 17 Fowl_adenovirus_A R-HSA-383280 Nuclear Receptor transcription pathway 21/574 52/10654 6.384708430203954e-14 1.0615930457678098e-12 6.777701188173689e-13 367/5915/6257/6097/5914/5467/2908/7181/6258/2100/7182/5468/9611/5469/5916/9975/8431/9612/6256/2099/7101 21 Fowl_adenovirus_A R-HSA-5663202 Diseases of signal transduction 59/574 377/10654 6.509293868982494e-14 1.0642695475786378e-12 6.794789214113305e-13 4089/10014/22938/1385/84441/5519/23493/8850/5906/10013/1387/2931/5518/22906/1956/4088/8841/5290/10046/6907/324/2335/79718/79885/1487/2033/6776/2100/6777/1499/83933/2648/9734/9611/3516/55869/816/3066/3065/6774/4851/9759/9612/1026/51564/4087/3674/7750/5245/6772/55534/2099/6934/3280/9794/4609/6233/4193/1488 59 Fowl_adenovirus_A R-HSA-69205 G1/S-Specific Transcription 16/574 28/10654 6.841238992597656e-14 1.1002058117603772e-12 7.024222951847463e-13 55957/898/5928/91750/286826/5934/1874/1869/1875/7027/3065/1876/983/132660/5933/5111 16 Fowl_adenovirus_A R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 18/574 37/10654 7.636339597021836e-14 1.2082659910771647e-12 7.71412913451272e-13 27327/6257/8841/192670/6907/4343/79718/2033/9611/26523/2874/192669/9682/9612/23028/6256/23112/57690 18 Fowl_adenovirus_A R-HSA-4641265 Repression of WNT target genes 11/574 12/10654 1.1570674713639774e-13 1.8017193482667648e-012 1.1503009949232523e-12 51176/7089/7090/1487/7091/3065/7088/83439/6934/1488/6932 11 Fowl_adenovirus_A R-HSA-8986944 Transcriptional Regulation by MECP2 22/574 62/10654 3.7504711701227706e-13 5.74876909045381e-12 3.670280174708961e-12 27327/1385/8841/6657/192670/25942/6907/4343/79718/5468/9611/26523/2874/816/192669/3066/3065/9612/4204/23112/57690/5566 22 Fowl_adenovirus_A R-HSA-8939211 ESR-mediated signaling 42/574 223/10654 6.416741160271443e-13 9.684343197271208e-12 6.1829327779133735e-12 27327/7514/1385/2353/8850/3725/2354/10524/1387/1386/6908/1956/5290/3169/192670/4343/7090/7764/2033/2100/595/3276/865/5469/26523/1105/8204/1655/192669/3065/2002/861/23028/57678/5451/6667/23112/2625/2099/57690/4609/7528 42 Fowl_adenovirus_A R-HSA-400253 Circadian Clock 23/574 70/10654 7.112781508193176e-13 1.0572179787178038e-11 6.749768735845198e-12 1385/3091/8945/1387/1386/23411/8841/2908/6907/1390/79718/2033/4209/79365/9611/5469/5501/8204/8553/6256/5499/6233/5054 23 Fowl_adenovirus_A R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 12/574 16/10654 7.989007446801385e-13 1.1697337769122626e-11 7.468121650976943e-12 22938/84441/8850/1387/10046/2033/2648/3516/4851/55534/3280/9794 12 Fowl_adenovirus_A R-HSA-9024446 NR1H2 and NR1H3-mediated signaling 19/574 47/10654 9.960435174679069e-13 1.4369392509353186e-11 9.174085029309668e-12 27327/6257/8841/192670/6907/4343/79718/2033/9611/26523/8204/2874/192669/9682/9612/23028/6256/23112/57690 19 Fowl_adenovirus_A R-HSA-1912408 Pre-NOTCH Transcription and Translation 26/574 93/10654 1.5602936012356373e-12 2.2183304678437104e-11 1.4162848096646896e-11 27327/22938/84441/8850/3725/51548/1387/10046/192670/4343/2033/595/2648/1869/7027/26523/3516/192669/4851/7157/861/23112/55534/57690/9794/1871 26 Fowl_adenovirus_A R-HSA-195721 Signaling by WNT 52/574 331/10654 1.899750150710561e-12 2.6623641397815147e-11 1.699776450635765e-11 27327/7514/57154/5519/90780/79577/9070/1460/26108/283149/51176/8945/10524/1387/5518/8295/6657/607/7089/192670/8607/4343/7015/51339/324/7090/1487/2033/6597/1499/26523/864/4772/7091/192669/3065/7088/1457/83439/8085/23112/6934/57690/4609/6233/4221/1488/123169/6932/55553/5929/5592 52 Fowl_adenovirus_A R-HSA-9012852 Signaling by NOTCH3 19/574 49/10654 2.4327410627469516e-12 3.361294341626422e-11 2.1460058299991642e-11 22938/84441/23493/8850/5087/1387/1956/10046/2033/2648/3516/4851/4904/6772/55534/3280/9794/6233/10320 19 Fowl_adenovirus_A R-HSA-8878166 Transcriptional regulation by RUNX2 29/574 121/10654 5.58705594427619e-12 7.612363724076308e-11 4.860085214684697e-11 4089/2736/57154/23493/4086/5925/367/860/10013/25/1019/8841/2908/2737/595/891/865/23314/9759/983/861/1026/10413/579/6772/2099/3280/6233/25925 29 Fowl_adenovirus_A R-HSA-5250913 Positive epigenetic regulation of rRNA expression 27/574 106/10654 6.534163574290466e-12 8.78084173476568e-11 5.606095640523182e-11 8467/57504/5931/8850/23451/5928/57459/6908/11335/9015/54815/2033/2648/2074/79101/3066/3065/7270/53615/9112/1107/9219/9013/9014/10919/1108/9188 27 Fowl_adenovirus_A R-HSA-9614085 FOXO-mediated transcription 21/574 65/10654 1.042493959866821e-11 1.3820088846342586e-10 8.82338415534507e-11 4089/8850/604/9314/1387/23411/4088/1649/2908/10628/25942/2033/5934/4802/4801/3066/3065/4800/1026/4087/23410 21 Fowl_adenovirus_A R-HSA-4570464 SUMOylation of RNA binding proteins 18/574 47/10654 1.1888484865393143e-11 1.555013820393423e-10 9.927927712152869e-11 1912/80012/9972/7341/4928/84733/6613/23636/5903/23225/8021/57332/53371/8535/1911/7329/6045/6015 18 Fowl_adenovirus_A R-HSA-201681 TCF dependent signaling in response to WNT 41/574 233/10654 1.2069763488684023e-11 1.557952366105135e-10 9.946688747599714e-11 7514/5519/90780/79577/9070/1460/26108/283149/51176/8945/10524/1387/5518/8295/6657/607/7089/8607/7015/51339/324/7090/1487/2033/6597/1499/864/7091/3065/7088/1457/83439/8085/6934/4609/6233/4221/123169/6932/55553/5929 41 Fowl_adenovirus_A R-HSA-390450 Folding of actin by CCT/TriC 9/574 10/10654 3.431070194070638e-11 4.371272545952332e-10 2.790822645894777e-10 10694/6950/22948/7203/10693/10576/908/10575/10574 9 Fowl_adenovirus_A R-HSA-8940973 RUNX2 regulates osteoblast differentiation 13/574 24/10654 4.0703073136779855e-11 5.119194198356543e-10 3.2683304340599206e-10 23493/5925/367/860/10013/25/8841/2737/865/23314/10413/3280/25925 13 Fowl_adenovirus_A R-HSA-1912422 Pre-NOTCH Expression and Processing 26/574 109/10654 7.966191349109997e-11 9.892194574021401e-10 6.315634713818052e-10 27327/22938/84441/8850/3725/51548/1387/10046/192670/4343/2033/595/2648/1869/7027/26523/3516/192669/4851/7157/861/23112/55534/57690/9794/1871 26 Fowl_adenovirus_A R-HSA-5250941 Negative epigenetic regulation of rRNA expression 26/574 110/10654 9.913698380577105e-11 1.2156672639182675e-9 7.761382284793918e-10 8467/64426/79685/1789/6908/23411/25942/11176/8932/9015/51742/79595/8819/79101/23378/10284/3066/3065/7270/9013/1786/6839/9014/23309/7343/29115 26 Fowl_adenovirus_A R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 10/574 14/10654 1.571466966055161e-10 1.880011089878186e-9 1.2002860652154307e-9 8841/25942/6907/79718/9611/2874/3065/9612/4204/5566 10 Fowl_adenovirus_A R-HSA-9005895 Pervasive developmental disorders 10/574 14/10654 1.571466966055161e-10 1.880011089878186e-9 1.2002860652154307e-9 8841/25942/6907/79718/9611/2874/3065/9612/4204/5566 10 Fowl_adenovirus_A R-HSA-69206 G1/S Transition 28/574 131/10654 2.3626131755985117e-10 2.792437982243542e-9 1.782821609995072e-9 55957/898/5519/1017/5925/5928/5518/91750/1019/4149/286826/5934/1874/595/1869/891/1875/7027/890/3065/1876/983/1026/132660/5933/5111/4609/6233 28 Fowl_adenovirus_A R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 17/574 49/10654 2.7818339405205726e-10 3.2487846376793833e-9 2.0741744293355144e-9 898/1017/5325/2033/5934/1874/3276/1869/891/7027/890/7157/983/1026/5933/5111/4869 17 Fowl_adenovirus_A R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 22/574 84/10654 3.343313404744143e-10 3.858577000063534e-9 2.4634940877062103e-9 112950/9314/1052/1051/1387/1019/8841/6907/688/4790/79718/2033/27332/5468/9611/5469/7026/1050/5970/9612/6256/896 22 Fowl_adenovirus_A R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 12/574 23/10654 4.185426038232057e-10 4.7743057482623815e-9 3.048137690022122e-9 4089/60436/7050/4088/142/9611/3065/6497/6498/9612/4087/6233 12 Fowl_adenovirus_A R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 13/574 28/10654 4.997255868350982e-10 5.6348367894854175e-9 3.5975405222853406e-9 10694/6950/22948/7203/10693/10576/908/7411/5204/10575/10471/10574/5202 13 Fowl_adenovirus_A R-HSA-73854 RNA Polymerase I Promoter Clearance 25/574 110/10654 5.580249794170445e-10 6.220710281910463e-9 3.971589267382075e-9 57504/5931/8850/5928/57459/6908/11335/8932/9015/54815/2648/2074/79101/3066/3065/7270/53615/9112/1107/9219/9013/9014/10919/7343/1108 25 Fowl_adenovirus_A R-HSA-73864 RNA Polymerase I Transcription 25/574 112/10654 8.37411132066941e-10 9.230340680423249e-9 5.893076565107391e-9 57504/5931/8850/5928/57459/6908/11335/8932/9015/54815/2648/2074/79101/3066/3065/7270/53615/9112/1107/9219/9013/9014/10919/7343/1108 25 Fowl_adenovirus_A R-HSA-9616222 Transcriptional regulation of granulopoiesis 22/574 90/10654 1.4016962625041798e-9 1.527848926129556e-8 9.75449445836242e-9 1385/1017/6688/51176/1051/2672/1019/5914/688/2033/1869/6886/865/7027/6774/1050/861/1026/6256/4297/5371/4609 22 Fowl_adenovirus_A R-HSA-186712 Regulation of beta-cell development 15/574 42/10654 1.9861784532473396e-9 2.14114402487433e-8 1.367005413166185e-8 6927/22938/84441/8850/1387/3642/10046/4821/2033/2648/3516/4851/55534/3280/9794 15 Fowl_adenovirus_A R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 13/574 31/10654 2.369071056209279e-9 2.5261507675448944e-8 1.6128115314010536e-8 1385/5519/2353/1432/3725/5518/1386/5601/5602/5599/5600/2002/4205 13 Fowl_adenovirus_A R-HSA-450341 Activation of the AP-1 family of transcription factors 8/574 10/10654 2.768418529749567e-9 2.920235029768092e-8 1.8644131581222325e-8 2353/1432/3725/1386/5601/5602/5599/5600 8 Fowl_adenovirus_A R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 13/574 32/10654 3.795357152674164e-9 3.960899326354632e-8 2.5288213951188436e-8 10694/6950/22948/7203/10693/10576/908/7411/5204/10575/10471/10574/5202 13 Fowl_adenovirus_A R-HSA-3232142 SUMOylation of ubiquitinylation proteins 14/574 38/10654 4.317630129154996e-9 4.412078288230262e-8 2.816874919788621e-8 9972/7341/4928/23636/5903/23225/8021/53371/7428/7329/5987/5371/51588/4193 14 Fowl_adenovirus_A R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 14/574 38/10654 4.317630129154996e-9 4.412078288230262e-8 2.816874919788621e-8 7341/1387/5308/1956/4605/2033/1026/7329/10765/2099/4609/3329/7528/4869 14 Fowl_adenovirus_A R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 10/574 18/10654 5.640677949808196e-9 5.7046444007854016e-8 3.642108931238064e-8 2033/5934/1874/3276/891/7027/7157/983/5933/5111 10 Fowl_adenovirus_A R-HSA-4615885 SUMOylation of DNA replication proteins 15/574 45/10654 5.969133025772019e-9 5.975223977839133e-8 3.814859452561064e-8 7153/5905/9972/7341/4928/6613/23636/5903/23225/7155/8021/53371/7329/5111/51588 15 Fowl_adenovirus_A R-HSA-427413 NoRC negatively regulates rRNA expression 23/574 107/10654 8.645179397180618e-9 8.566586857206247e-8 5.4693054134210176e-8 8467/64426/79685/1789/6908/25942/11176/8932/9015/51742/79595/8819/79101/10284/3066/3065/7270/9013/1786/9014/23309/7343/29115 23 Fowl_adenovirus_A R-HSA-69202 Cyclin E associated events during G1/S transition 20/574 83/10654 1.029307395902319e-8 1.009750555380175e-7 6.446714742756629e-8 55957/898/1017/5925/5928/91750/1019/4149/286826/5934/1874/595/1869/1875/7027/890/1026/132660/4609/6233 20 Fowl_adenovirus_A R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 20/574 85/10654 1.5962070710913658e-8 1.550375382911515e-7 9.898313781129366e-8 55957/898/1017/5925/5928/91750/1019/4149/286826/5934/1874/595/1869/1875/7027/890/1026/132660/4609/6233 20 Fowl_adenovirus_A R-HSA-4090294 SUMOylation of intracellular receptors 12/574 30/10654 1.8892851727324995e-8 1.8170477984809626e-7 1.1600873867655698e-7 367/7341/6613/5914/2908/7181/5468/9759/6256/7329/2099/51588 12 Fowl_adenovirus_A R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 16/574 56/10654 2.2783191494130935e-8 2.1699330927905289e-7 1.3853856861530817e-7 1385/1387/1386/2551/8841/6907/79718/4209/3054/9611/5469/23409/3418/6256/23408/23410 16 Fowl_adenovirus_A R-HSA-2197563 NOTCH2 intracellular domain regulates transcription 8/574 12/10654 2.7646045580128253e-8 2.5846917105760673e-7 1.6501867780382638e-7 1385/84441/10046/2033/3516/55534/3280/9794 8 Fowl_adenovirus_A R-HSA-450294 MAP kinase activation 17/574 64/10654 2.766489598475913e-8 2.5846917105760673e-7 1.6501867780382638e-7 1385/5519/2353/1432/3725/8945/23118/5518/1386/5601/5602/4790/5599/5600/2002/4205/6233 17 Fowl_adenovirus_A R-HSA-3214847 HATs acetylate histones 26/574 142/10654 3.2194604394385354e-8 2.979519519895475e-7 1.9022631196285283e-7 9643/5931/8850/23774/5077/10524/1387/27154/57634/1386/8295/10629/8607/11091/64769/2033/79595/7862/3054/55929/2648/7994/84289/10856/6871/10933 26 Fowl_adenovirus_A R-HSA-5693532 DNA Double-Strand Break Repair 28/574 166/10654 6.039723329398346e-8 5.537353818822222e-7 3.535302883415658e-7 672/8467/1017/3364/7341/51548/10524/25/545/79184/472/6613/5599/5591/5981/10038/142/5883/322/10714/890/7486/7157/9682/7329/5111/51588/6233 28 Fowl_adenovirus_A R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 13/574 39/10654 6.254924828856193e-8 5.681556719544375e-7 3.6273686872996436e-7 898/10694/6950/8841/22948/7203/10693/10576/908/6774/7157/10575/10574 13 Fowl_adenovirus_A R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 20/574 92/10654 6.656198965348131e-8 5.990579068813317e-7 3.8246628530971874e-7 672/1017/1460/3364/1432/10524/545/472/6908/8851/5300/5600/5883/890/7486/7157/1457/6233/4193/6878 20 Fowl_adenovirus_A R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 19/574 85/10654 8.84853522152767e-8 7.750368796713075e-7 4.948194038354289e-7 1385/5519/2353/1432/3725/8945/23118/5518/1386/5601/5602/4790/5599/5600/2002/5970/4792/4205/6233 19 Fowl_adenovirus_A R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 19/574 85/10654 8.84853522152767e-8 7.750368796713075e-7 4.948194038354289e-7 1385/5519/2353/1432/3725/8945/23118/5518/1386/5601/5602/4790/5599/5600/2002/5970/4792/4205/6233 19 Fowl_adenovirus_A R-HSA-975871 MyD88 cascade initiated on plasma membrane 19/574 85/10654 8.84853522152767e-8 7.750368796713075e-7 4.948194038354289e-7 1385/5519/2353/1432/3725/8945/23118/5518/1386/5601/5602/4790/5599/5600/2002/5970/4792/4205/6233 19 Fowl_adenovirus_A R-HSA-448424 Interleukin-17 signaling 17/574 72/10654 1.816153186091897e-7 1.5766781199611956e-6 1.0066242624356578e-6 1385/5519/2353/1432/3725/8945/23118/5518/1386/5601/5602/4790/5599/5600/2002/4205/6233 17 Fowl_adenovirus_A R-HSA-73894 DNA Repair 42/574 334/10654 2.2239199064084733e-7 1.9137416036725546e-6 1.221821185884618e-6 672/9318/8467/1017/8930/3364/7341/51548/10524/124739/25/545/79184/472/6613/93973/8607/1642/5599/5591/2033/8450/84164/5981/10038/142/2074/5883/322/328/10714/890/7486/7157/9682/7329/5111/51588/1643/6233/8451/7528 42 Fowl_adenovirus_A R-HSA-6806003 Regulation of TP53 Expression and Degradation 12/574 37/10654 2.8571000937979016e-7 2.437230601752819e-6 1.556040783349887e-6 5519/1017/5518/472/1616/639/1029/890/7157/983/6233/4193 12 Fowl_adenovirus_A R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 22/574 119/10654 3.1069735289045024e-7 2.6275353722890663e-6 1.677540153991088e-6 112950/6257/1387/8841/25942/6907/79718/2033/34/5468/4802/9611/5469/4801/2874/405/4800/9612/6256/6667/23309/2274 22 Fowl_adenovirus_A R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 19/574 92/10654 3.338398499874924e-7 2.7991187422028212e-6 1.78708691626233e-6 1385/5519/2353/1432/3725/8945/23118/5518/1386/5601/5602/4790/5599/5600/2002/5970/4792/4205/6233 19 Fowl_adenovirus_A R-HSA-3232118 SUMOylation of transcription factors 9/574 20/10654 3.53654313224539e-7 2.940126112485362e-6 1.8771125456610231e-6 7341/6613/6670/1029/7157/9112/7329/51588/4193 9 Fowl_adenovirus_A R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 19/574 93/10654 3.988591970333621e-7 3.2606739357477352e-6 2.0817651073232497e-6 1385/5519/2353/1432/3725/8945/23118/5518/1386/5601/5602/4790/5599/5600/2002/5970/4792/4205/6233 19 Fowl_adenovirus_A R-HSA-975155 MyD88 dependent cascade initiated on endosome 19/574 93/10654 3.988591970333621e-7 3.2606739357477352e-6 2.0817651073232497e-6 1385/5519/2353/1432/3725/8945/23118/5518/1386/5601/5602/4790/5599/5600/2002/5970/4792/4205/6233 19 Fowl_adenovirus_A R-HSA-2173789 TGF-beta receptor signaling activates SMADs 11/574 32/10654 4.617901828147107e-7 3.743935283811828e-6 2.3903015117420863e-6 4089/7514/57154/11171/4088/5501/9040/4087/5499/4092/6233 11 Fowl_adenovirus_A R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 19/574 94/10654 4.752462481943118e-7 3.82144729080836e-6 2.4397887633789087e-6 1385/5519/2353/1432/3725/8945/23118/5518/1386/5601/5602/4790/5599/5600/2002/5970/4792/4205/6233 19 Fowl_adenovirus_A R-HSA-5617472 Activation of anterior HOX genes in hindbrain development during early embryogenesis 22/574 122/10654 4.871573165942834e-7 3.85404296434671e-6 2.460599349521211e-6 5931/9070/5928/5087/5915/3725/1387/58508/8841/5914/8726/11091/7403/2033/23512/9611/5916/2146/8085/6256/7528/5929 22 Fowl_adenovirus_A R-HSA-5619507 Activation of HOX genes during differentiation 22/574 122/10654 4.871573165942834e-7 3.85404296434671e-6 2.460599349521211e-6 5931/9070/5928/5087/5915/3725/1387/58508/8841/5914/8726/11091/7403/2033/23512/9611/5916/2146/8085/6256/7528/5929 22 Fowl_adenovirus_A R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 19/574 95/10654 5.647594683963372e-7 4.362433373990605e-6 2.785179309538505e-6 1385/5519/2353/1432/3725/8945/23118/5518/1386/5601/5602/4790/5599/5600/2002/5970/4792/4205/6233 19 Fowl_adenovirus_A R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 19/574 95/10654 5.647594683963372e-7 4.362433373990605e-6 2.785179309538505e-6 1385/5519/2353/1432/3725/8945/23118/5518/1386/5601/5602/4790/5599/5600/2002/5970/4792/4205/6233 19 Fowl_adenovirus_A R-HSA-390466 Chaperonin-mediated protein folding 19/574 95/10654 5.647594683963372e-7 4.362433373990605e-6 2.785179309538505e-6 898/10694/1460/6950/8841/22948/7203/10693/10576/908/7411/6774/7157/5204/1457/10575/10471/10574/5202 19 Fowl_adenovirus_A R-HSA-156711 Polo-like kinase mediated events 8/574 16/10654 5.926073318893359e-7 4.541779629558113e-6 2.8996822571887734e-6 55957/5928/91750/4605/286826/2033/891/132660 8 Fowl_adenovirus_A R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 19/574 97/10654 7.91403232889129e-7 6.018345515226633e-6 3.842390237201401e-6 1385/5519/2353/1432/3725/8945/23118/5518/1386/5601/5602/4790/5599/5600/2002/5970/4792/4205/6233 19 Fowl_adenovirus_A R-HSA-4085377 SUMOylation of SUMOylation proteins 11/574 34/10654 9.27675759407911e-7 6.936394378346896e-6 4.42851510823156e-6 9972/7341/4928/6613/23636/5903/23225/8021/53371/7329/51588 11 Fowl_adenovirus_A R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 19/574 98/10654 9.333374698693072e-7 6.936394378346896e-6 4.42851510823156e-6 1385/5519/2353/1432/3725/8945/23118/5518/1386/5601/5602/4790/5599/5600/2002/5970/4792/4205/6233 19 Fowl_adenovirus_A R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 19/574 98/10654 9.333374698693072e-7 6.936394378346896e-6 4.42851510823156e-6 1385/5519/2353/1432/3725/8945/23118/5518/1386/5601/5602/4790/5599/5600/2002/5970/4792/4205/6233 19 Fowl_adenovirus_A R-HSA-166166 MyD88-independent TLR4 cascade 19/574 99/10654 1.098065422924198e-6 8.038822237974911e-6 5.132356061586e-6 1385/5519/2353/1432/3725/8945/23118/5518/1386/5601/5602/4790/5599/5600/2002/5970/4792/4205/6233 19 Fowl_adenovirus_A R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 19/574 99/10654 1.098065422924198e-6 8.038822237974911e-6 5.132356061586e-6 1385/5519/2353/1432/3725/8945/23118/5518/1386/5601/5602/4790/5599/5600/2002/5970/4792/4205/6233 19 Fowl_adenovirus_A R-HSA-195253 Degradation of beta-catenin by the destruction complex 17/574 82/10654 1.3110461828772983e-6 9.526935595575034e-6 6.082436481964854e-6 5519/51176/8945/5518/7089/324/7090/1487/1499/7091/3065/7088/83439/6934/6233/1488/6932 17 Fowl_adenovirus_A R-HSA-391251 Protein folding 19/574 101/10654 1.5091995303265967e-6 1.0886211318017583e-5 6.950260994925117e-6 898/10694/1460/6950/8841/22948/7203/10693/10576/908/7411/6774/7157/5204/1457/10575/10471/10574/5202 19 Fowl_adenovirus_A R-HSA-69242 S Phase 25/574 161/10654 1.5317728767656405e-6 1.0968388263555425e-5 7.002726559166777e-6 55957/898/1017/5925/5928/114799/91750/1019/4149/157570/286826/5934/1874/595/5981/1869/1875/7027/10714/890/1026/132660/5111/4609/6233 25 Fowl_adenovirus_A R-HSA-177243 Interactions of Rev with host cellular proteins 11/574 36/10654 1.7650374099903157e-6 1.2456846756838126e-5 7.953027330134326e-6 7514/5905/9972/4928/23636/5903/23225/8021/53371/5901/4869 11 Fowl_adenovirus_A R-HSA-6804757 Regulation of TP53 Degradation 11/574 36/10654 1.7650374099903157e-6 1.2456846756838126e-5 7.953027330134326e-6 5519/1017/5518/472/1616/1029/890/7157/983/6233/4193 11 Fowl_adenovirus_A R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 17/574 84/10654 1.8690063687040557e-6 1.3096394626419133e-5 8.361344281044459e-6 9318/7341/6613/93973/8607/1642/8450/5981/10038/142/10714/7329/5111/1643/6233/8451/7528 17 Fowl_adenovirus_A R-HSA-427389 ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression 16/574 76/10654 2.165502289376055e-6 1.5066366992041915e-5 9.619065787075422e-6 57504/5931/5928/57459/11335/54815/2074/3066/3065/7270/53615/9112/1107/9219/10919/1108 16 Fowl_adenovirus_A R-HSA-1592230 Mitochondrial biogenesis 18/574 95/10654 2.5518559417122783e-6 1.7629370977603837e-5 1.125540611800449e-5 1385/1432/1387/1386/2551/8841/6907/79718/4209/5600/3054/9611/5469/23409/3418/6256/23408/23410 18 Fowl_adenovirus_A R-HSA-6804760 Regulation of TP53 Activity through Methylation 8/574 19/10654 3.0120107084582673e-6 2.066281472026266e-5 1.3192096956442171e-5 472/79813/10419/2033/7157/10919/6233/4193 8 Fowl_adenovirus_A R-HSA-5696394 DNA Damage Recognition in GG-NER 11/574 38/10654 3.2030986101167823e-6 2.182110928142058e-5 1.3931605796926062e-5 9318/93973/8607/1642/8450/10038/142/1643/6233/8451/7528 11 Fowl_adenovirus_A R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 9/574 25/10654 3.3727215852797354e-6 2.281820603558221e-5 1.4568198499030437e-5 10694/6950/22948/7203/10693/10576/908/10575/10574 9 Fowl_adenovirus_A R-HSA-3214858 RMTs methylate histone arginines 16/574 79/10654 3.709099238711218e-6 2.4922098309422638e-5 1.591142067075108e-5 5931/6595/6598/1019/10419/6599/11091/6605/6597/6602/595/3276/6601/1788/79084/55170 16 Fowl_adenovirus_A R-HSA-1989781 PPARA activates gene expression 20/574 117/10654 3.8132583747060083e-6 2.5447663031201318e-5 1.6246965506266202e-5 112950/6257/1387/8841/6907/79718/2033/34/5468/4802/9611/5469/4801/2874/405/4800/9612/6256/6667/2274 20 Fowl_adenovirus_A R-HSA-4086398 Ca2+ pathway 14/574 62/10654 3.905361558403367e-6 2.5886214113470964e-5 1.65269568083215e-5 27327/51176/192670/4343/1499/26523/4772/192669/83439/23112/6934/57690/6932/5592 14 Fowl_adenovirus_A R-HSA-5688426 Deubiquitination 36/574 297/10654 3.940221256935314e-6 2.5941993644654652e-5 1.656256904186868e-5 4089/672/64426/4086/8850/3091/367/79184/57695/93973/8295/4088/10318/3607/8607/221937/324/2033/3054/2648/890/991/7157/4792/10869/983/4087/63891/4092/2625/2099/1643/4609/6233/4193/7528 36 Fowl_adenovirus_A R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 6/574 10/10654 4.155791400578117e-6 2.708496693066905e-5 1.7292296071407354e-5 8850/1387/23411/10628/2033/23410 6 Fowl_adenovirus_A R-HSA-5693538 Homology Directed Repair 22/574 138/10654 4.169041800745185e-6 2.708496693066905e-5 1.7292296071407354e-5 672/1017/3364/7341/51548/10524/25/545/79184/472/6613/5981/10038/142/5883/10714/890/7486/7329/5111/51588/6233 22 Fowl_adenovirus_A R-HSA-3371556 Cellular response to heat stress 17/574 89/10654 4.310880006235424e-6 2.782219267182204e-5 1.7762975094945133e-5 9972/4928/1410/10013/1387/545/472/23636/5903/23225/23411/8021/2033/53371/816/3297/3308 17 Fowl_adenovirus_A R-HSA-2173788 Downregulation of TGF-beta receptor signaling 9/574 26/10654 4.91365998463509e-6 3.1505231666189695e-5 2.0114397597921418e-5 7514/57154/11171/4088/5501/4087/5499/4092/6233 9 Fowl_adenovirus_A R-HSA-5696398 Nucleotide Excision Repair 19/574 111/10654 6.50963462535403e-6 4.1467217970599376e-5 2.6474590581583374e-5 9318/7341/6613/93973/8607/1642/2033/8450/5981/10038/142/2074/10714/7329/5111/1643/6233/8451/7528 19 Fowl_adenovirus_A R-HSA-165054 Rev-mediated nuclear export of HIV RNA 10/574 34/10654 7.707069610899618e-6 4.877829218253242e-5 3.114231863147893e-5 7514/5905/9972/4928/23636/5903/23225/8021/53371/5901 10 Fowl_adenovirus_A R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 11/574 42/10654 9.356576131743106e-6 5.883846913615376e-5 3.7565201068739184e-5 10694/1460/6950/22948/7203/10693/10576/908/1457/10575/10574 11 Fowl_adenovirus_A R-HSA-9614657 FOXO-mediated transcription of cell death genes 7/574 16/10654 9.48757453671536e-6 5.928223325170553e-5 3.784852061244143e-5 604/1387/1649/2033/4802/4801/4800 7 Fowl_adenovirus_A R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 20/574 132/10654 2.4520661819734584e-5 1.5224537496936474e-4 9.720049155724234e-5 672/1017/3364/7341/51548/10524/25/545/79184/472/6613/5981/5883/10714/890/7486/7329/5111/51588/6233 20 Fowl_adenovirus_A R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 9/574 31/10654 2.487554778868205e-5 1.534774363565855e-4 9.798709655257081e-5 7514/9972/4928/23636/5903/23225/8021/53371/5901 9 Fowl_adenovirus_A R-HSA-9013694 Signaling by NOTCH4 15/574 82/10654 2.6981274400201384e-5 1.6542893866623474e-4 1.0561748860605147e-4 22938/84441/23493/8850/1387/4088/10046/2033/2648/3516/4851/55534/3280/9794/6233 15 Fowl_adenovirus_A R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF) 12/574 55/10654 2.7740907666661343e-5 1.685427134023145e-4 1.0760546646748981e-4 1387/8720/6907/79718/4802/5469/4801/5901/4800/6256/57678/6667 12 Fowl_adenovirus_A R-HSA-168254 Influenza Infection 22/574 155/10654 2.7832741662767534e-5 1.685427134023145e-4 1.0760546646748981e-4 3839/7514/3840/9972/6154/4928/6202/23636/5903/23225/6189/8021/6166/51121/6143/6217/53371/3843/5901/3836/6229/6233 22 Fowl_adenovirus_A R-HSA-168276 NS1 Mediated Effects on Host Pathways 10/574 40/10654 3.716163240325627e-5 2.2365375084413747e-4 1.4279090267960918e-4 3839/3840/9972/4928/23636/5903/23225/8021/53371/3836 10 Fowl_adenovirus_A R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 9/574 33/10654 4.319566126660016e-5 2.5374217785948956e-4 1.6200074663490132e-4 7514/9972/4928/23636/5903/23225/8021/53371/5901 9 Fowl_adenovirus_A R-HSA-180746 Nuclear import of Rev protein 9/574 33/10654 4.319566126660016e-5 2.5374217785948956e-4 1.6200074663490132e-4 9972/4928/23636/5903/23225/8021/53371/5901/4869 9 Fowl_adenovirus_A R-HSA-180910 Vpr-mediated nuclear import of PICs 9/574 33/10654 4.319566126660016e-5 2.5374217785948956e-4 1.6200074663490132e-4 9972/4928/23636/5903/23225/8021/8815/53371/3836 9 Fowl_adenovirus_A R-HSA-1980145 Signaling by NOTCH2 9/574 33/10654 4.319566126660016e-5 2.5374217785948956e-4 1.6200074663490132e-4 1385/84441/10046/2033/3516/55534/3280/9794/6233 9 Fowl_adenovirus_A R-HSA-5693565 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 14/574 76/10654 4.593357537945352e-5 2.68219270519309e-4 1.7124359242340128e-4 672/8467/7341/10524/25/79184/472/5599/322/7157/9682/7329/51588/6233 14 Fowl_adenovirus_A R-HSA-5696400 Dual Incision in GG-NER 10/574 41/10654 4.680907672632425e-5 2.717142264409709e-4 1.7347493399042616e-4 1642/8450/5981/10038/142/10714/5111/1643/6233/8451 10 Fowl_adenovirus_A R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 6/574 14/10654 4.933072440254039e-5 2.8466729787583603e-4 1.817447741146225e-4 898/1017/1869/890/7157/1026 6 Fowl_adenovirus_A R-HSA-5693606 DNA Double Strand Break Response 14/574 77/10654 5.341621014882247e-5 3.0644036348534995e-4 1.9564570660849103e-4 672/8467/7341/10524/25/79184/472/5599/322/7157/9682/7329/51588/6233 14 Fowl_adenovirus_A R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 19/574 129/10654 5.804454720601016e-5 3.2989216368994537e-4 2.1061842094051986e-4 1385/5519/2353/1432/3725/8945/23118/5518/1386/5601/5602/4790/5599/5600/2002/5970/4792/4205/6233 19 Fowl_adenovirus_A R-HSA-168253 Host Interactions with Influenza Factors 10/574 42/10654 5.8512983162130984e-5 3.2989216368994537e-4 2.1061842094051986e-4 3839/3840/9972/4928/23636/5903/23225/8021/53371/3836 10 Fowl_adenovirus_A R-HSA-2426168 Activation of gene expression by SREBF (SREBP) 10/574 42/10654 5.8512983162130984e-5 3.2989216368994537e-4 2.1061842094051986e-4 1387/6907/79718/4802/5469/4801/4800/6256/57678/6667 10 Fowl_adenovirus_A R-HSA-1368108 BMAL1:CLOCK,NPAS2 activates circadian gene expression 8/574 27/10654 6.026138390439786e-5 3.37808100629796e-4 2.1567232134205548e-4 1387/6907/79718/79365/5469/8553/6256/5054 8 Fowl_adenovirus_A R-HSA-5693607 Processing of DNA double-strand break ends 16/574 98/10654 6.289160364273515e-5 3.505492225768363e-4 2.2380684310662329e-4 672/1017/3364/7341/51548/10524/545/79184/472/6613/5883/890/7486/7329/51588/6233 16 Fowl_adenovirus_A R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 9/574 35/10654 7.178965703883796e-5 3.978850483338985e-4 2.540282244312137e-4 9972/4928/23636/5903/23225/8021/891/53371/983 9 Fowl_adenovirus_A R-HSA-5696395 Formation of Incision Complex in GG-NER 10/574 43/10654 7.261718703200204e-5 4.0021045212580903e-4 2.555128698050929e-4 7341/6613/1642/8450/10038/142/7329/1643/6233/8451 10 Fowl_adenovirus_A R-HSA-2980766 Nuclear Envelope Breakdown 11/574 52/10654 8.078113087743158e-5 4.427167005070412e-4 2.826508254752825e-4 9972/4928/23636/5903/23225/8021/8815/891/53371/983/2010 11 Fowl_adenovirus_A R-HSA-168255 Influenza Life Cycle 20/574 144/10654 8.709140784566862e-5 4.7464817275889404e-4 3.0303735478463644e-4 7514/9972/6154/4928/6202/23636/5903/23225/6189/8021/6166/51121/6143/6217/53371/3843/5901/3836/6229/6233 20 Fowl_adenovirus_A R-HSA-176033 Interactions of Vpr with host cellular proteins 9/574 36/10654 9.120360822316476e-5 4.94313478822788e-4 3.155925960615472e-4 9972/4928/23636/5903/23225/8021/8815/53371/3836 9 Fowl_adenovirus_A R-HSA-1169408 ISG15 antiviral mechanism 13/574 72/10654 1.0582847232682167e-4 5.653224891934977e-4 3.609280337680467e-4 3839/3840/9972/4928/23636/5903/23225/5300/8021/53371/3836/6772/6233 13 Fowl_adenovirus_A R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 8/574 29/10654 1.058738086858256e-4 5.653224891934977e-4 3.609280337680467e-4 4089/4088/2908/25942/3066/3065/4087/23410 8 Fowl_adenovirus_A R-HSA-113510 E2F mediated regulation of DNA replication 7/574 22/10654 1.0648602996329503e-4 5.653224891934977e-4 3.609280337680467e-4 5519/5925/5518/1869/891/7027/983 7 Fowl_adenovirus_A R-HSA-69620 Cell Cycle Checkpoints 32/574 293/10654 1.0661025535249448e-4 5.653224891934977e-4 3.609280337680467e-4 701/672/7514/898/5519/1017/9184/5905/3364/7341/10524/4928/545/79184/5518/472/699/5903/5883/891/1029/5501/890/7486/991/7157/983/1026/51588/6233/4193/8379 32 Fowl_adenovirus_A R-HSA-525793 Myogenesis 8/574 30/10654 1.37635136080634e-4 7.259143467478601e-4 4.634573059874206e-4 6925/4654/1432/25/4209/5600/1499/4205 8 Fowl_adenovirus_A R-HSA-2514853 Condensation of Prometaphase Chromosomes 5/574 11/10654 1.5709261018564125e-4 8.197226095325216e-4 5.233488413239447e-4 1460/10051/891/1457/983 5 Fowl_adenovirus_A R-HSA-4755510 SUMOylation of immune response proteins 5/574 11/10654 1.5709261018564125e-4 8.197226095325216e-4 5.233488413239447e-4 7341/5970/4792/7329/51588 5 Fowl_adenovirus_A R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 8/574 31/10654 1.7685586244305213e-4 9.133087468826336e-4 5.830985615056247e-4 9972/4928/23636/5903/23225/8021/53371/3836 8 Fowl_adenovirus_A R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 6/574 17/10654 1.7688956361641223e-4 9.133087468826336e-4 5.830985615056247e-4 4089/9314/4088/5934/1026/4087 6 Fowl_adenovirus_A R-HSA-452723 Transcriptional regulation of pluripotent stem cells 7/574 24/10654 1.9665491624290595e-4 0.0010100443603889568 6.448590529872087e-4 4089/9314/5087/6657/6774/4087/57167 7 Fowl_adenovirus_A R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 16/574 108/10654 2.048957648881434e-4 0.0010468892987253577 6.683825663840203e-4 2353/604/3091/1052/6097/6657/2335/7431/595/6774/7157/1026/5451/6772/2625/4609 16 Fowl_adenovirus_A R-HSA-5368286 Mitochondrial translation initiation 14/574 87/10654 2.0928749529456852e-4 0.0010528770917126755 6.722054504737828e-4 64951/64969/51081/7818/51650/56945/51023/64963/51649/64965/10240/51116/60488/55037 14 Fowl_adenovirus_A R-HSA-5389840 Mitochondrial translation elongation 14/574 87/10654 2.0928749529456852e-4 0.0010528770917126755 6.722054504737828e-4 64951/64969/51081/7818/51650/56945/51023/64963/51649/64965/10240/51116/60488/55037 14 Fowl_adenovirus_A R-HSA-5419276 Mitochondrial translation termination 14/574 87/10654 2.0928749529456852e-4 0.0010528770917126755 6.722054504737828e-4 64951/64969/51081/7818/51650/56945/51023/64963/51649/64965/10240/51116/60488/55037 14 Fowl_adenovirus_A R-HSA-1368082 RORA activates gene expression 6/574 18/10654 2.533311265687422e-4 0.0012615118536240413 8.0540753571147e-4 1387/6907/79718/2033/5469/6256 6 Fowl_adenovirus_A R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 6/574 18/10654 2.533311265687422e-4 0.0012615118536240413 8.0540753571147e-4 5290/6776/6777/6774/7750/6772 6 Fowl_adenovirus_A R-HSA-381033 ATF6 (ATF6-alpha) activates chaperones 5/574 12/10654 2.5740284524391745e-4 0.001275314096890318 8.142195264228116e-4 1649/8720/4802/4801/4800 5 Fowl_adenovirus_A R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 7/574 25/10654 2.6056673558981193e-4 0.0012780798380680276 8.159853035575688e-4 1385/5519/1432/5518/5600/2002/4205 7 Fowl_adenovirus_A R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 7/574 25/10654 2.6056673558981193e-4 0.0012780798380680276 8.159853035575688e-4 7514/5519/1017/5518/891/890/983 7 Fowl_adenovirus_A R-HSA-5687128 MAPK6/MAPK4 signaling 14/574 89/10654 2.6745161808279316e-4 0.0013053235688518412 8.333789618186013e-4 27327/7514/3725/192670/4343/26523/192669/983/896/23112/57690/4609/6233/5566 14 Fowl_adenovirus_A R-HSA-3371453 Regulation of HSF1-mediated heat shock response 12/574 69/10654 2.7959830962201015e-4 0.001357851196728673 8.669150298337469e-4 9972/4928/545/472/23636/5903/23225/23411/8021/53371/3297/3308 12 Fowl_adenovirus_A R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 13/574 80/10654 3.167188299040357e-4 0.0015305476459894533 9.77172433460727e-4 3839/3840/9972/4928/23636/5903/23225/5300/8021/53371/3836/6772/6233 13 Fowl_adenovirus_A R-HSA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 5/574 13/10654 3.998232076394286e-4 0.0019226792485013697 0.0012275273918754385 5519/5925/5518/1869/7027 5 Fowl_adenovirus_A R-HSA-5368287 Mitochondrial translation 14/574 93/10654 4.2627967048261594e-4 0.002039904179236323 0.0013023692114873247 64951/64969/51081/7818/51650/56945/51023/64963/51649/64965/10240/51116/60488/55037 14 Fowl_adenovirus_A R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress 7/574 27/10654 4.381450968702288e-4 0.002086506504998517 0.0013321222924771903 1051/467/1649/4802/4801/23016/4800 7 Fowl_adenovirus_A R-HSA-8848021 Signaling by PTK6 10/574 54/10654 5.310435768602936e-4 0.0025045853312497504 0.0015990431590681919 898/1017/3091/1019/1956/6421/2908/595/6774/6233 10 Fowl_adenovirus_A R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 10/574 54/10654 5.310435768602936e-4 0.0025045853312497504 0.0015990431590681919 898/1017/3091/1019/1956/6421/2908/595/6774/6233 10 Fowl_adenovirus_A R-HSA-449147 Signaling by Interleukins 42/574 461/10654 5.552364734749827e-4 0.0026037875552130186 0.0016623784487920443 1385/5519/2353/604/3091/1052/1432/3725/8945/23118/5518/6950/1386/5601/6097/4088/6657/5290/5602/4790/2335/5599/6776/5600/7431/6597/6777/595/2002/6774/7157/5970/4792/4205/6850/1026/5451/6772/2625/4609/6233/5566 42 Fowl_adenovirus_A R-HSA-201451 Signaling by BMP 7/574 28/10654 5.573857151832149e-4 0.0026037875552130186 0.0016623784487920443 4089/4093/57154/4086/6497/4092/4090 7 Fowl_adenovirus_A R-HSA-5685938 HDR through Single Strand Annealing (SSA) 8/574 37/10654 6.503259221029134e-4 0.003023553220772313 0.0019303762716449662 672/3364/10524/25/545/472/5883/7486 8 Fowl_adenovirus_A R-HSA-168898 Toll-like Receptor Cascades 19/574 155/10654 6.567477046361896e-4 0.0030390070672080285 0.0019402427222370048 1385/5519/2353/1432/3725/8945/23118/5518/1386/5601/5602/4790/5599/5600/2002/5970/4792/4205/6233 19 Fowl_adenovirus_A R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 15/574 110/10654 7.894696261967612e-4 0.0036360079967090266 0.0023213957380137035 2353/1017/3725/1051/79813/1019/4790/1021/1029/890/6774/5970/1026/10919/6233 15 Fowl_adenovirus_A R-HSA-5685942 HDR through Homologous Recombination (HRR) 11/574 67/10654 8.255688539063936e-4 0.003781151570630626 0.0024140621111918264 672/3364/10524/545/472/5981/5883/10714/7486/5111/6233 11 Fowl_adenovirus_A R-HSA-6784531 tRNA processing in the nucleus 10/574 57/10654 8.286927499343371e-4 0.003781151570630626 0.0024140621111918264 1653/9972/4928/23636/5903/23225/8021/53371/5901/51493 10 Fowl_adenovirus_A R-HSA-168273 Influenza Viral RNA Transcription and Replication 17/574 134/10654 8.41704159377904e-4 0.003822739723841314 0.0024406139124261836 9972/6154/4928/6202/23636/5903/23225/6189/8021/6166/51121/6143/6217/53371/3843/6229/6233 17 Fowl_adenovirus_A R-HSA-198753 ERK/MAPK targets 6/574 22/10654 8.464991905989536e-4 0.0038268004883759152 0.0024432064923908675 5519/1432/5518/5600/2002/4205 6 Fowl_adenovirus_A R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 7/574 30/10654 8.725222557884473e-4 0.00390842161154551 0.0024953171939155307 1642/8450/5981/10714/5111/6233/8451 7 Fowl_adenovirus_A R-HSA-180786 Extension of Telomeres 7/574 30/10654 8.725222557884473e-4 0.00390842161154551 0.0024953171939155307 1736/8607/7015/5981/10714/10856/5111 7 Fowl_adenovirus_A R-HSA-453274 Mitotic G2-G2/M phases 22/574 198/10654 9.871841493438748e-4 0.004401943865937914 0.002810404635691892 55957/7514/5519/1017/5928/8945/5518/91750/4605/286826/2033/55142/1869/891/890/7157/983/1026/132660/6233/1871/5566 22 Fowl_adenovirus_A R-HSA-913531 Interferon Signaling 22/574 199/10654 0.0010553962411367494 0.004684813178982584 0.0029910014931000986 3839/3840/1958/9972/7341/4928/23636/5903/6737/23225/5300/8021/53371/3454/816/3663/4261/3836/5371/6772/3659/6233 22 Fowl_adenovirus_A R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 7/574 31/10654 0.0010754249538475241 0.004730905290244041 0.0030204288295457957 9972/4928/23636/5903/23225/8021/53371 7 Fowl_adenovirus_A R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 7/574 31/10654 0.0010754249538475241 0.004730905290244041 0.0030204288295457957 9972/4928/23636/5903/23225/8021/53371 7 Fowl_adenovirus_A R-HSA-5620922 BBSome-mediated cargo-targeting to cilium 6/574 23/10654 0.0010937270636781295 0.004789938613697522 0.0030581184346263487 10694/6950/22948/7203/10576/10575 6 Gallid_herpesvirus_2 R-HSA-8856828 Clathrin-mediated endocytosis 122/642 146/10654 7.619455374163185e-128 8.838568234029294e-125 4.178669736777915e-125 8301/5869/10097/9318/9856/127833/409/163/1080/10092/143425/7311/29978/11037/7037/2017/3949/1173/867/3575/29763/112574/9341/1759/6845/1213/58513/2580/85439/1956/6857/1211/915/161/84251/60/29924/917/160/23149/950/1129/23048/9146/6572/6455/338/4036/7018/4074/25977/3482/408/6453/26119/7316/274/51429/5868/3312/1175/1950/10618/8218/85021/9829/9322/8673/8674/10093/10987/10109/115548/8027/1856/6869/9892/920/6456/273/5286/29993/9185/55707/551/185/10552/154/10254/26130/3267/6457/8871/10094/8322/5878/2060/1212/554/54874/22905/3092/8976/7314/30011/23208/50618/6233/26052/1601/11252/90019/4952/8867/7474/9026/10980/1785/10096/29988/6844/22848 122 Gallid_herpesvirus_2 R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 86/642 106/10654 2.9219770013617722e-87 1.694746660789828e-84 8.012368514260439e-85 8301/9318/9856/127833/409/163/1080/143425/7311/29978/11037/7037/3949/1173/867/3575/9341/6845/1213/58513/85439/1956/6857/1211/915/161/84251/29924/917/160/23149/950/1129/9146/6572/6455/338/4036/7018/4074/25977/3482/408/6453/26119/7316/1175/1950/10618/8218/85021/8673/8674/10987/115548/8027/1856/6869/9892/920/6456/9185/55707/551/185/154/10254/3267/6457/8322/2060/1212/554/22905/7314/30011/23208/50618/6233/1601/90019/7474/10980/29988/6844/22848 86 Gallid_herpesvirus_2 R-HSA-8943724 Regulation of PTEN gene transcription 45/642 61/10654 2.339373857740131e-42 9.045578916595174e-40 4.276539578535467e-40 2475/10014/1912/80012/57504/5931/1958/5928/3725/6591/84733/1386/57459/8841/8726/54815/23512/57332/5468/1822/23186/23466/6615/2146/3065/3066/5978/7157/53615/9112/1107/9219/8535/23028/1911/51564/6045/5594/1108/57167/2122/6015/5595/84232/7101 45 Gallid_herpesvirus_2 R-HSA-1257604 PIP3 activates AKT signaling 87/642 264/10654 4.194511320414157e-42 1.2164082829201057e-39 5.7508957840415165e-40 2475/10014/7409/1912/27327/80012/1385/57504/5931/7311/1958/5928/941/3725/2932/2261/6591/84733/3932/2064/1386/57459/6199/1956/8841/5290/192670/3667/4343/8726/54815/2534/23512/2100/57332/7316/5728/5468/1950/1822/23186/23466/26523/842/6615/5781/3630/192669/2146/3065/3066/5978/2263/7157/53615/9112/1107/1457/9219/8535/23028/1026/10273/207/1911/51564/942/4734/50852/6045/5371/23112/6714/2099/57690/5594/1108/57167/940/7314/2122/6233/6015/5595/4193/84232/7101 87 Gallid_herpesvirus_2 R-HSA-9006925 Intracellular signaling by second messengers 92/642 305/10654 6.486092915913285e-41 1.5047735564918823e-38 7.114219808822783e-39 2475/10014/7409/1912/27327/80012/1385/57504/5931/7311/1958/5928/941/3725/2932/2261/6591/84733/3932/3838/2064/1386/57459/6199/1956/8841/5290/192670/3667/4343/8726/54815/5335/2534/23512/2100/57332/7316/5728/5468/1950/1822/23186/23466/26523/842/6615/5781/3630/192669/5567/2146/3065/3066/5978/2263/7157/53615/9112/1107/1457/9219/8535/23028/1026/10273/207/1911/51564/942/4734/50852/6045/5371/23112/6714/2099/57690/5594/1108/57167/940/7314/2122/6233/6015/5568/5595/4193/84232/7101/5566 92 Gallid_herpesvirus_2 R-HSA-6807070 PTEN Regulation 62/642 140/10654 6.476927137536479e-39 1.2522059132570527e-36 5.9201386643096595e-37 2475/10014/1912/27327/80012/57504/5931/7311/1958/5928/3725/6591/84733/1386/57459/8841/192670/4343/8726/54815/23512/57332/7316/5728/5468/1822/23186/23466/26523/6615/192669/2146/3065/3066/5978/7157/53615/9112/1107/1457/9219/8535/23028/10273/207/1911/51564/4734/6045/5371/23112/57690/5594/1108/57167/7314/2122/6233/6015/5595/84232/7101 62 Gallid_herpesvirus_2 R-HSA-449147 Signaling by Interleukins 110/642 461/10654 2.7674694741247076e-38 4.586092271406658e-36 2.168197888750335e-36 7409/1385/7124/2353/5743/604/6196/7311/5598/3091/2939/3552/1432/941/3725/5777/6347/4208/867/3932/3575/10538/4318/3726/4312/3383/6845/302/3558/4067/1386/301/5601/351/6464/4088/3636/6657/5290/836/6778/3576/7040/3667/3320/5602/4790/3662/4843/2335/5599/2534/5600/7431/6597/375/7316/595/5604/3565/6175/3312/2920/3559/3551/79155/6352/6351/3458/3181/6416/5781/2002/6774/4314/3569/920/7157/5970/4792/3162/4205/356/6850/6648/1026/6775/207/1234/942/5451/3586/7422/3606/3553/6772/2625/5594/8809/5609/4609/7314/6233/5595/4582/3146/3603/2919/6844/5566 110 Gallid_herpesvirus_2 R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 110/642 473/10654 3.6641675009378277e-37 5.31304287635985e-35 2.511883247353432e-35 2475/7409/2962/1385/163/6196/7311/23545/5598/5795/3178/1432/5777/2261/4208/627/1173/867/2963/3932/4318/3479/5437/2064/1759/9402/1213/5441/5434/5440/4670/58513/4067/387/6464/1956/535/1211/161/60/8851/5290/6778/29924/160/5438/55824/3667/9146/3320/6455/5431/5335/2335/3845/2534/5600/5435/4846/7316/5604/1499/4803/3265/1175/5433/1950/9611/6300/1445/5439/5603/1020/5781/3630/5327/5567/8027/2002/6774/2263/5430/6456/4205/83737/5432/10048/10273/207/10254/6457/4734/5436/10413/7422/2060/6772/6714/2099/5594/7314/30011/6233/26052/5568/5595/3187/25920/1785/5566 110 Gallid_herpesvirus_2 R-HSA-8939211 ESR-mediated signaling 72/642 223/10654 3.476346882730098e-34 4.4806248710743487e-32 2.1183353519326097e-32 3727/2962/27327/1385/2353/8850/3725/2354/2963/1387/4318/3838/5437/5441/5434/5440/1386/6908/6464/1956/5290/3169/192670/54331/5438/4343/3320/5431/3845/2033/2100/5435/4846/595/3265/5433/1950/5469/26523/8204/2782/5439/1655/192669/3065/8202/2002/4314/5430/2770/5432/8648/861/23028/207/5436/5451/6667/23112/2771/2625/2773/6714/2099/57690/5594/2957/10498/4609/5595/7528/3326 72 Gallid_herpesvirus_2 R-HSA-9006931 Signaling by Nuclear Receptors 77/642 299/10654 4.39232941757165e-29 4.6377119248839704e-27 2.192602461764563e-27 3727/2962/27327/1385/2353/8850/3725/2354/2963/1387/4318/3838/5437/5441/5434/5440/1386/6908/6464/1956/8841/5290/3169/192670/54331/5438/1374/4343/3320/5431/3845/2033/2100/5435/4846/595/3265/5433/1950/9611/5469/26523/8204/2782/5439/1655/192669/3065/8202/2002/4314/5430/2770/5432/8648/9612/861/23028/207/5436/5451/6667/23112/2771/2625/2773/6714/2099/57690/5594/2957/10062/10498/4609/5595/7528/3326 77 Gallid_herpesvirus_2 R-HSA-2559583 Cellular Senescence 62/642 195/10654 4.397830273596869e-29 4.6377119248839704e-27 2.192602461764563e-27 1912/27327/80012/5931/2353/5925/6196/7311/5598/3552/5928/1432/3725/1051/84733/1019/5601/192670/3576/4343/8726/5602/3490/4790/29855/5599/23512/5600/57332/7316/3159/2114/7290/23466/4217/26523/3456/890/25842/2113/6416/192669/2146/6774/3569/7157/5970/8535/1026/1911/23135/6045/6667/23112/57690/5594/5609/7314/6233/6015/5595/4193 62 Gallid_herpesvirus_2 R-HSA-5663202 Diseases of signal transduction 85/642 377/10654 1.3412869987785714e-27 1.296577432152619e-25 6.129916897926629e-26 2475/4089/10014/7409/2962/409/1385/8850/7311/941/2932/2261/867/2963/1387/3932/5437/2064/5441/5434/5440/6199/6464/1956/4088/8841/60/5290/7040/5438/3667/3320/5431/5335/2335/3845/2534/2033/408/2100/5435/7316/5604/1499/55294/5728/3265/10018/5433/1950/9734/9611/842/1445/5439/5781/3065/3066/6774/4851/2263/5430/5432/9612/1026/207/51564/4087/942/5436/50852/8322/5245/6772/6714/2099/6934/5594/940/4609/7314/6233/7415/5595/4193 85 Gallid_herpesvirus_2 R-HSA-5663205 Infectious disease 83/642 383/10654 1.0680679314475553e-25 9.530452311378185e-24 4.5057764557423184e-24 2962/127833/163/7311/6204/6223/5905/6749/6146/6141/1173/867/2963/3932/3837/3838/5437/6203/1213/5441/5434/5440/164/6908/6857/1211/7852/161/999/3921/160/6206/7040/5438/7251/9146/3320/6455/5431/919/2534/375/5435/7316/5604/1499/3159/6175/1175/5433/6129/6872/2547/2960/2961/5439/2959/6416/8027/5430/920/6456/5432/567/6874/1234/10254/6457/5436/6176/926/2060/6714/5609/2957/940/7314/30011/6233/25920/3326/4869/6844 83 Gallid_herpesvirus_2 R-HSA-9018519 Estrogen-dependent gene expression 51/642 150/10654 1.3116132054322198e-25 1.086765227358125e-23 5.137973534061552e-24 3727/2962/27327/2353/8850/3725/2354/2963/1387/3838/5437/5441/5434/5440/1386/6908/3169/192670/5438/4343/3320/5431/2033/5435/595/5433/5469/26523/8204/5439/1655/192669/3065/8202/5430/5432/8648/861/23028/5436/5451/6667/23112/2625/2099/57690/2957/10498/4609/7528/3326 51 Gallid_herpesvirus_2 R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 42/642 108/10654 6.4225332052598044e-24 4.966759012067581e-22 2.348168280659901e-22 7124/2353/5743/604/3091/3552/6347/10538/4318/3726/4312/3383/301/6657/6778/3576/7040/3320/3662/4843/2335/7431/595/3565/3312/6774/4314/3569/7157/3162/356/1026/207/5451/3586/7422/3606/3553/6772/2625/4609/4582 42 Gallid_herpesvirus_2 R-HSA-166520 Signaling by NTRKs 40/642 101/10654 3.4713619782010627e-23 2.5167374341957704e-21 1.1898549938439168e-21 1385/163/6196/5598/1432/4208/627/1173/1759/1213/387/6464/1211/161/8851/5290/160/3667/5335/3845/2534/5600/5604/4803/3265/1175/6300/5603/1020/5781/2002/6774/6456/4205/6714/5594/26052/5595/25920/1785 40 Gallid_herpesvirus_2 R-HSA-389948 PD-1 signaling 20/642 23/10654 4.486305280286569e-22 3.0612436030190704e-20 1.4472848613184536e-20 5133/3120/3123/29126/5777/3932/80380/915/3117/917/3127/919/3115/3122/1445/916/5781/3119/920/3113 20 Gallid_herpesvirus_2 R-HSA-2871796 FCERI mediated MAPK activation 23/642 32/10654 1.0026639726243203e-21 6.461612268023397e-20 3.054900173902169e-20 7409/2353/3725/27040/9402/4067/5601/2206/6464/2205/5602/5335/3845/5599/3265/6416/3937/6850/2207/5594/5609/5595/4214 23 Gallid_herpesvirus_2 R-HSA-187037 Signaling by NTRK1 (TRKA) 34/642 80/10654 4.540970214107203e-21 2.7691358542358745e-19 1.3091831034999006e-19 1385/163/6196/5598/1432/4208/1173/1759/1213/387/6464/1211/161/5290/160/3667/5335/3845/5600/5604/4803/3265/1175/6300/5603/2002/6774/6456/4205/6714/5594/26052/5595/1785 34 Gallid_herpesvirus_2 R-HSA-2559580 Oxidative Stress Induced Senescence 42/642 125/10654 4.7743721624756455e-21 2.7691358542358745e-19 1.3091831034999006e-19 1912/27327/80012/5931/2353/7311/5928/1432/3725/84733/1019/5601/192670/4343/8726/5602/5599/23512/5600/57332/7316/23466/4217/26523/3456/6416/192669/2146/7157/8535/1911/23135/6045/23112/57690/5594/5609/7314/6233/6015/5595/4193 42 Gallid_herpesvirus_2 R-HSA-202427 Phosphorylation of CD3 and TCR zeta chains 19/642 22/10654 6.660665146194687e-21 3.6792245569456367e-19 1.7394519003345522e-19 26191/5795/3120/3123/3932/5788/915/3117/917/55824/3127/919/3115/3122/1445/916/3119/920/3113 19 Gallid_herpesvirus_2 R-HSA-8878171 Transcriptional regulation by RUNX1 58/642 239/10654 1.1066145810681662e-20 5.834876881995785e-19 2.758594242758443e-19 1912/27327/80012/8850/7311/6688/9070/7161/860/25/1387/84733/58508/6598/3558/6599/4773/5588/192670/6604/2624/8289/4343/11091/2033/6605/6597/6602/57332/7316/595/50943/6601/3559/23466/26523/3458/5781/192669/3065/1457/83737/8535/861/8085/1911/6045/10413/5371/23112/2625/6714/2099/57690/7314/6233/6015/5929 58 Gallid_herpesvirus_2 R-HSA-3700989 Transcriptional Regulation by TP53 73/642 365/10654 1.7481937599682325e-20 8.816977224187608e-19 4.1684620088945045e-19 2475/672/2962/27327/5931/2353/604/7311/7161/5928/6749/1432/3725/2963/1387/5437/5441/5434/5440/1386/57459/1616/6908/4513/4436/8851/192670/5300/5438/4343/5431/54815/2033/5600/5435/10128/7316/5728/5433/26523/6872/890/5439/1020/192669/3065/3066/5430/7157/53615/1107/8795/1457/54971/9219/5432/6874/1026/207/54205/5436/641/5371/23112/57690/1108/10498/7314/6233/7832/4193/25920/4869 73 Gallid_herpesvirus_2 R-HSA-5654738 Signaling by FGFR2 32/642 73/10654 2.111220089708853e-20 1.0204230433592789e-18 4.82432309972944e-19 2962/7311/3178/867/2963/5437/5441/5434/5440/4670/6464/5290/5438/5431/5335/3845/5435/7316/3265/5433/5439/5781/2263/5430/5432/5436/6714/5594/7314/6233/5595/3187 32 Gallid_herpesvirus_2 R-HSA-388841 Costimulation by the CD28 family 31/642 70/10654 5.783105840951898e-20 2.6833611102016803e-18 1.2686307971098688e-18 2475/7409/5133/3120/3123/941/29126/5777/3932/9402/4067/80380/915/3117/5290/917/3127/919/2534/3115/3122/1445/916/5781/3119/920/207/942/3113/6714/940 31 Gallid_herpesvirus_2 R-HSA-177929 Signaling by EGFR 26/642 49/10654 1.8335512586477273e-19 8.18045946165909e-18 3.8675311973905506e-18 7311/867/58513/6464/1956/5290/29924/55824/9146/6455/5335/3845/7316/3265/1950/1445/5781/8027/6456/10254/6457/2060/6714/7314/30011/6233 26 Gallid_herpesvirus_2 R-HSA-2262752 Cellular responses to stress 83/642 479/10654 4.740837976896375e-19 2.036804464148072e-17 9.629538346834352e-18 2475/1912/27327/80012/5931/2353/5925/6196/7311/5598/3091/3552/5928/367/1432/3725/2932/1051/1387/84733/2034/1019/5601/23411/192670/2908/3576/573/4343/3320/8726/5602/3490/4790/29855/5599/2033/23512/5600/57332/7316/3159/3312/2114/112399/7290/23466/4217/26523/3456/890/25842/2113/405/6416/192669/2146/6774/3569/7157/5970/8535/6648/1026/1911/23135/54205/6045/6667/7422/23112/57690/5594/5609/7314/6233/6015/7415/5595/4193/2950/2056/3326 83 Gallid_herpesvirus_2 R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 41/642 134/10654 7.187235589496489e-19 2.97756902993426e-17 1.40772546696529e-17 7409/3702/2353/7311/3725/27040/9402/4067/5601/2206/6464/4773/5588/5290/2205/5602/5335/4790/3845/5599/2534/5530/7316/3265/3551/4772/6416/3937/5970/4792/6850/695/2207/5532/5594/5609/7314/6233/5595/4775/4214 41 Gallid_herpesvirus_2 R-HSA-190236 Signaling by FGFR 33/642 87/10654 1.1925927489555304e-18 4.770370995822122e-17 2.255320588768898e-17 2962/7311/3178/2261/867/2963/5437/5441/5434/5440/4670/6464/5290/5438/5431/5335/3845/5435/7316/3265/5433/5439/5781/2263/5430/5432/5436/6714/5594/7314/6233/5595/3187 33 Gallid_herpesvirus_2 R-HSA-8953897 Cellular responses to external stimuli 83/642 493/10654 2.9888519859083514e-18 1.1556894345512292e-16 5.4638311742394775e-17 2475/1912/27327/80012/5931/2353/5925/6196/7311/5598/3091/3552/5928/367/1432/3725/2932/1051/1387/84733/2034/1019/5601/23411/192670/2908/3576/573/4343/3320/8726/5602/3490/4790/29855/5599/2033/23512/5600/57332/7316/3159/3312/2114/112399/7290/23466/4217/26523/3456/890/25842/2113/405/6416/192669/2146/6774/3569/7157/5970/8535/6648/1026/1911/23135/54205/6045/6667/7422/23112/57690/5594/5609/7314/6233/6015/7415/5595/4193/2950/2056/3326 83 Gallid_herpesvirus_2 R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 47/642 182/10654 4.045985989983437e-18 1.513981854316383e-16 7.157754501804314e-17 672/1912/80012/7153/7020/5905/367/7341/1387/84733/9063/2516/1616/2908/5465/2033/23512/57332/5468/142/8204/1655/3065/3066/23314/7157/9112/5970/4792/1107/8648/8535/9612/7421/1911/51564/6304/7329/6045/641/5371/2099/10062/6015/4193/8554/4869 47 Gallid_herpesvirus_2 R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 39/642 129/10654 8.362827492836156e-18 3.031524966153107e-16 1.433234580186723e-16 1385/2353/3665/6196/7311/5598/1432/3725/4208/1759/1386/5601/351/7099/5602/4790/5599/5600/7316/5604/3551/79155/6416/5781/2002/5970/4792/4205/3661/695/5594/5609/7314/6233/26052/5595/3146/1785/4214 39 Gallid_herpesvirus_2 R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 33/642 93/10654 1.2869138157494806e-17 4.2817814374703386e-16 2.0243267957550333e-16 1385/2353/3665/6196/7311/5598/1432/3725/4208/1386/5601/351/7099/5602/4790/5599/5600/7316/5604/3551/79155/6416/2002/5970/4792/4205/5594/5609/7314/6233/5595/3146/4214 33 Gallid_herpesvirus_2 R-HSA-975155 MyD88 dependent cascade initiated on endosome 33/642 93/10654 1.2869138157494806e-17 4.2817814374703386e-16 2.0243267957550333e-16 1385/2353/3665/6196/7311/5598/1432/3725/4208/1386/5601/351/7099/5602/4790/5599/5600/7316/5604/3551/79155/6416/2002/5970/4792/4205/5594/5609/7314/6233/5595/3146/4214 33 Gallid_herpesvirus_2 R-HSA-166166 MyD88-independent TLR4 cascade 34/642 99/10654 1.3288287219735534e-17 4.2817814374703386e-16 2.0243267957550333e-16 1385/2353/3665/6196/7311/5598/1432/3725/4208/1386/5601/351/7099/5602/4790/5599/5600/7316/5604/3551/79155/6416/5781/2002/5970/4792/4205/3661/5594/5609/7314/6233/5595/3146 34 Gallid_herpesvirus_2 R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 34/642 99/10654 1.3288287219735534e-17 4.2817814374703386e-16 2.0243267957550333e-16 1385/2353/3665/6196/7311/5598/1432/3725/4208/1386/5601/351/7099/5602/4790/5599/5600/7316/5604/3551/79155/6416/5781/2002/5970/4792/4205/3661/5594/5609/7314/6233/5595/3146 34 Gallid_herpesvirus_2 R-HSA-2990846 SUMOylation 47/642 188/10654 1.659479311564735e-17 5.202691895716467e-16 2.4597118672125945e-16 672/1912/80012/7153/7020/5905/367/7341/1387/84733/9063/2516/1616/2908/5465/2033/23512/57332/5468/142/8204/1655/3065/3066/23314/7157/9112/5970/4792/1107/8648/8535/9612/7421/1911/51564/6304/7329/6045/641/5371/2099/10062/6015/4193/8554/4869 47 Gallid_herpesvirus_2 R-HSA-202430 Translocation of ZAP-70 to Immunological synapse 16/642 19/10654 2.0678157870342098e-17 6.246904023845499e-16 2.953391103832582e-16 26191/3120/3123/3932/915/3117/917/3127/919/3115/3122/916/3119/920/3113/7535 16 Gallid_herpesvirus_2 R-HSA-202403 TCR signaling 37/642 119/10654 2.100252214913573e-17 6.246904023845499e-16 2.953391103832582e-16 3702/26191/7311/5795/3120/3123/27040/3932/9402/5788/915/3117/5588/5290/917/55824/3127/5335/4790/919/3115/7316/5728/3122/3551/1445/916/3119/3937/920/5970/4792/50852/3113/7535/7314/6233 37 Gallid_herpesvirus_2 R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 33/642 95/10654 2.7091670987071537e-17 7.664960571951947e-16 3.6238152976288247e-16 1385/2353/6196/7311/5598/1432/3725/4208/1386/5601/351/7099/5602/4790/5599/5600/7316/5604/3551/79155/6416/2002/5970/4792/4205/695/5594/5609/7314/6233/5595/3146/4214 33 Gallid_herpesvirus_2 R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 33/642 95/10654 2.7091670987071537e-17 7.664960571951947e-16 3.6238152976288247e-16 1385/2353/6196/7311/5598/1432/3725/4208/1386/5601/351/7099/5602/4790/5599/5600/7316/5604/3551/79155/6416/2002/5970/4792/4205/695/5594/5609/7314/6233/5595/3146/4214 33 Gallid_herpesvirus_2 R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 31/642 85/10654 5.079751118002711e-17 1.3392071129279875e-15 6.331460125548834e-16 1385/2353/6196/7311/5598/1432/3725/4208/1386/5601/351/5602/4790/5599/5600/7316/5604/3551/79155/6416/2002/5970/4792/4205/5594/5609/7314/6233/5595/3146/4214 31 Gallid_herpesvirus_2 R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 31/642 85/10654 5.079751118002711e-17 1.3392071129279875e-15 6.331460125548834e-16 1385/2353/6196/7311/5598/1432/3725/4208/1386/5601/351/5602/4790/5599/5600/7316/5604/3551/79155/6416/2002/5970/4792/4205/5594/5609/7314/6233/5595/3146/4214 31 Gallid_herpesvirus_2 R-HSA-975871 MyD88 cascade initiated on plasma membrane 31/642 85/10654 5.079751118002711e-17 1.3392071129279875e-15 6.331460125548834e-16 1385/2353/6196/7311/5598/1432/3725/4208/1386/5601/351/5602/4790/5599/5600/7316/5604/3551/79155/6416/2002/5970/4792/4205/5594/5609/7314/6233/5595/3146/4214 31 Gallid_herpesvirus_2 R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 33/642 97/10654 5.578427351485858e-17 1.437994606160799e-15 6.798504444734812e-16 1385/2353/3665/6196/7311/5598/1432/3725/4208/1386/5601/351/7099/5602/4790/5599/5600/7316/5604/3551/79155/6416/2002/5970/4792/4205/5594/5609/7314/6233/5595/3146/4214 33 Gallid_herpesvirus_2 R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 32/642 92/10654 7.936986397090257e-17 1.8993313778008287e-15 8.979597530256188e-16 1385/2353/6196/7311/5598/1432/3725/4208/1386/5601/351/7099/5602/4790/5599/5600/7316/5604/3551/79155/6416/2002/5970/4792/4205/5594/5609/7314/6233/5595/3146/4214 32 Gallid_herpesvirus_2 R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 33/642 98/10654 7.94145756802602e-17 1.8993313778008287e-15 8.979597530256188e-16 1385/2353/6196/7311/5598/1432/3725/4208/1386/5601/351/7099/5602/4790/5599/5600/7316/5604/3551/79155/6416/2002/5970/4792/4205/695/5594/5609/7314/6233/5595/3146/4214 33 Gallid_herpesvirus_2 R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 33/642 98/10654 7.94145756802602e-17 1.8993313778008287e-15 8.979597530256188e-16 1385/2353/6196/7311/5598/1432/3725/4208/1386/5601/351/7099/5602/4790/5599/5600/7316/5604/3551/79155/6416/2002/5970/4792/4205/695/5594/5609/7314/6233/5595/3146/4214 33 Gallid_herpesvirus_2 R-HSA-202433 Generation of second messenger molecules 20/642 33/10654 8.186773180175986e-17 1.8993313778008287e-15 8.979597530256188e-16 3702/3120/3123/27040/3932/9402/915/3117/917/3127/5335/919/3115/3122/916/3119/3937/920/3113/7535 20 Gallid_herpesvirus_2 R-HSA-2559585 Oncogene Induced Senescence 20/642 33/10654 8.186773180175986e-17 1.8993313778008287e-15 8.979597530256188e-16 27327/5925/7311/1019/192670/4343/7316/2114/26523/2113/192669/7157/6667/23112/57690/5594/7314/6233/5595/4193 20 Gallid_herpesvirus_2 R-HSA-8876384 Listeria monocytogenes entry into host cells 16/642 20/10654 9.766657884422667e-17 2.2214359109667242e-15 1.0502432936603115e-15 7311/867/999/9146/6455/7316/1499/8027/6456/10254/6457/2060/6714/7314/30011/6233 16 Gallid_herpesvirus_2 R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 32/642 94/10654 1.6356145656632558e-16 3.64867864647957e-15 1.7250105034626644e-15 1385/2353/3665/6196/7311/5598/1432/3725/4208/1386/5601/351/5602/4790/5599/5600/7316/5604/3551/79155/6416/2002/5970/4792/4205/3661/5594/5609/7314/6233/5595/3146 32 Gallid_herpesvirus_2 R-HSA-199992 trans-Golgi Network Vesicle Budding 28/642 72/10654 2.384969156949893e-16 5.21993249445637e-15 2.467862821789264e-15 8301/7037/6845/1213/164/351/2580/1211/9146/4074/25977/3482/408/375/9685/51429/3312/10618/9829/8673/6456/5286/5878/1212/4952/9026/1785/6844 28 Gallid_herpesvirus_2 R-HSA-5617472 Activation of anterior HOX genes in hindbrain development during early embryogenesis 36/642 122/10654 3.7495542448803264e-16 7.908150771020325e-15 3.738789974320862e-15 5931/9070/5928/3725/22976/1387/58508/5437/23054/9063/5441/5434/5440/3213/8841/5438/8726/5431/11091/7403/2033/23512/5435/5433/9611/9935/5439/2146/8202/5430/5432/1959/8085/5436/7528/5929 36 Gallid_herpesvirus_2 R-HSA-5619507 Activation of HOX genes during differentiation 36/642 122/10654 3.7495542448803264e-16 7.908150771020325e-15 3.738789974320862e-15 5931/9070/5928/3725/22976/1387/58508/5437/23054/9063/5441/5434/5440/3213/8841/5438/8726/5431/11091/7403/2033/23512/5435/5433/9611/9935/5439/2146/8202/5430/5432/1959/8085/5436/7528/5929 36 Gallid_herpesvirus_2 R-HSA-450294 MAP kinase activation 26/642 64/10654 7.987322315862715e-16 1.6545167654287055e-14 7.822170914594877e-15 1385/2353/6196/7311/5598/1432/3725/4208/1386/5601/5602/4790/5599/5600/7316/5604/3551/79155/6416/2002/4205/5594/5609/7314/6233/5595 26 Gallid_herpesvirus_2 R-HSA-400253 Circadian Clock 27/642 70/10654 1.0515599852973752e-15 2.140016812184132e-14 1.0117502351614636e-14 1385/7311/3091/4208/1387/23054/1386/23411/8841/2908/6604/1374/1390/5465/2033/406/4209/7316/9611/5469/8204/23373/8648/551/10498/7314/6233 27 Gallid_herpesvirus_2 R-HSA-8851708 Signaling by FGFR2 IIIa TM 15/642 19/10654 1.3265343892216547e-15 2.6530687784433093e-14 1.2543092863602216e-14 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/2263/5430/5432/5436 15 Gallid_herpesvirus_2 R-HSA-168898 Toll-like Receptor Cascades 40/642 155/10654 1.3949716341707439e-15 2.7426560943018015e-14 1.29666408814087e-14 1385/2353/3665/6196/7311/5598/1432/3725/4208/1759/1386/5601/351/7099/5602/338/4790/5599/5600/7316/5604/3551/79155/6416/5781/2002/5970/4792/4205/3661/695/5594/5609/7314/6233/26052/5595/3146/1785/4214 40 Gallid_herpesvirus_2 R-HSA-432722 Golgi Associated Vesicle Biogenesis 24/642 56/10654 2.4196234083267178e-15 4.677938589431654e-14 2.2116206942775786e-14 8301/7037/6845/1213/164/2580/1211/25977/3482/408/375/9685/51429/3312/10618/9829/8673/6456/5286/5878/4952/9026/1785/6844 24 Gallid_herpesvirus_2 R-HSA-6803529 FGFR2 alternative splicing 17/642 26/10654 2.785161517261585e-15 5.2963727213499e-14 2.5040019853205973e-14 2962/3178/2963/5437/5441/5434/5440/4670/5438/5431/5435/5433/5439/5430/5432/5436/3187 17 Gallid_herpesvirus_2 R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 20/642 38/10654 3.601785151581271e-15 6.738823831990765e-14 3.1859593615854703e-14 1912/80012/84733/6598/6599/6604/8289/2033/6605/6597/6602/57332/6601/23466/1457/8535/861/1911/6045/6015 20 Gallid_herpesvirus_2 R-HSA-162906 HIV Infection 49/642 233/10654 5.9642031746675704e-15 1.098170743272124e-13 5.191896163745705e-14 2962/163/7311/5905/6749/1173/2963/3932/3837/5437/5441/5434/5440/164/6908/7852/161/160/5438/7251/5431/919/2534/375/5435/7316/3159/1175/5433/6872/2547/2960/2961/5439/2959/5430/920/5432/567/6874/1234/5436/926/2957/940/7314/6233/25920/4869 49 Gallid_herpesvirus_2 R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 13/642 15/10654 1.1548379477490913e-14 2.0931437802952279e-13 9.895897545678891e-14 7311/867/9146/6455/7316/8027/6456/10254/6457/2060/7314/30011/6233 13 Gallid_herpesvirus_2 R-HSA-448424 Interleukin-17 signaling 26/642 72/10654 2.3140826118611588e-14 4.129747430398376e-13 1.9524486490358927e-13 1385/2353/6196/7311/5598/1432/3725/4208/1386/5601/5602/4790/5599/5600/7316/5604/3551/79155/6416/2002/4205/5594/5609/7314/6233/5595 26 Gallid_herpesvirus_2 R-HSA-2871809 FCERI mediated Ca+2 mobilization 18/642 33/10654 3.85226773912589e-14 6.770652389978836e-13 3.2010071644092323e-13 7409/3702/27040/9402/4067/2206/6464/4773/2205/5335/5530/4772/3937/6850/695/2207/5532/4775 18 Gallid_herpesvirus_2 R-HSA-167161 HIV Transcription Initiation 21/642 47/10654 4.9743797699915806e-14 8.014278518319769e-13 3.7889647078444644e-13 2962/2963/5437/5441/5434/5440/6908/5438/5431/5435/5433/6872/2960/2961/5439/2959/5430/5432/6874/5436/2957 21 Gallid_herpesvirus_2 R-HSA-167162 RNA Polymerase II HIV Promoter Escape 21/642 47/10654 4.9743797699915806e-14 8.014278518319769e-13 3.7889647078444644e-13 2962/2963/5437/5441/5434/5440/6908/5438/5431/5435/5433/6872/2960/2961/5439/2959/5430/5432/6874/5436/2957 21 Gallid_herpesvirus_2 R-HSA-73776 RNA Polymerase II Promoter Escape 21/642 47/10654 4.9743797699915806e-14 8.014278518319769e-13 3.7889647078444644e-13 2962/2963/5437/5441/5434/5440/6908/5438/5431/5435/5433/6872/2960/2961/5439/2959/5430/5432/6874/5436/2957 21 Gallid_herpesvirus_2 R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 21/642 47/10654 4.9743797699915806e-14 8.014278518319769e-13 3.7889647078444644e-13 2962/2963/5437/5441/5434/5440/6908/5438/5431/5435/5433/6872/2960/2961/5439/2959/5430/5432/6874/5436/2957 21 Gallid_herpesvirus_2 R-HSA-75953 RNA Polymerase II Transcription Initiation 21/642 47/10654 4.9743797699915806e-14 8.014278518319769e-13 3.7889647078444644e-13 2962/2963/5437/5441/5434/5440/6908/5438/5431/5435/5433/6872/2960/2961/5439/2959/5430/5432/6874/5436/2957 21 Gallid_herpesvirus_2 R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 21/642 47/10654 4.9743797699915806e-14 8.014278518319769e-13 3.7889647078444644e-13 2962/2963/5437/5441/5434/5440/6908/5438/5431/5435/5433/6872/2960/2961/5439/2959/5430/5432/6874/5436/2957 21 Gallid_herpesvirus_2 R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 15/642 23/10654 1.3370763023504307e-13 2.1246691927760265e-12 1.0044942372380308e-12 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/25920 15 Gallid_herpesvirus_2 R-HSA-177504 Retrograde neurotrophin signalling 12/642 14/10654 1.6915328995157065e-13 2.6515921127543508e-12 1.2536111531261494e-12 163/1173/1759/1213/1211/161/160/4803/1175/6456/26052/1785 12 Gallid_herpesvirus_2 R-HSA-182971 EGFR downregulation 17/642 31/10654 1.7773485605887815e-13 2.748965773710649e-12 1.2996471579884283e-12 7311/867/58513/1956/29924/9146/6455/7316/1950/8027/6456/10254/6457/2060/7314/30011/6233 17 Gallid_herpesvirus_2 R-HSA-3899300 SUMOylation of transcription cofactors 20/642 45/10654 2.277456655724754e-13 3.4761180534746243e-12 1.6434278637570592e-12 1912/80012/7341/1387/84733/9063/1616/2033/57332/8204/1655/8648/8535/9612/1911/7329/6045/6015/8554/4869 20 Gallid_herpesvirus_2 R-HSA-3247509 Chromatin modifying enzymes 51/642 274/10654 2.738352259927456e-13 4.072421309635704e-12 1.925346190853178e-12 84678/57504/5931/8850/9070/5928/1387/58508/6598/1019/1386/57459/51317/8841/6599/60/6604/8289/8726/54815/11091/4790/7403/2033/23512/6605/6597/6602/595/6601/9611/23186/2146/3065/3066/5978/53615/9112/11143/5970/1107/9219/8648/9612/23028/8085/23135/1108/10498/2122/5929 51 Gallid_herpesvirus_2 R-HSA-4839726 Chromatin organization 51/642 274/10654 2.738352259927456e-13 4.072421309635704e-12 1.925346190853178e-12 84678/57504/5931/8850/9070/5928/1387/58508/6598/1019/1386/57459/51317/8841/6599/60/6604/8289/8726/54815/11091/4790/7403/2033/23512/6605/6597/6602/595/6601/9611/23186/2146/3065/3066/5978/53615/9112/11143/5970/1107/9219/8648/9612/23028/8085/23135/1108/10498/2122/5929 51 Gallid_herpesvirus_2 R-HSA-2682334 EPH-Ephrin signaling 28/642 92/10654 3.217133262218626e-13 4.7238918787007675e-12 2.2333463419265875e-12 10627/10097/163/10092/1173/4318/1759/1213/4067/6383/387/1211/161/60/160/2534/6453/3265/1175/8218/10093/10109/10552/10094/1212/6714/8976/10096 28 Gallid_herpesvirus_2 R-HSA-203927 MicroRNA (miRNA) biogenesis 15/642 24/10654 3.3687691970935494e-13 4.884715335785647e-12 2.3093799364286044e-12 5437/5441/5434/5440/192670/5438/5431/5435/5433/26523/5439/192669/5430/5432/5436 15 Gallid_herpesvirus_2 R-HSA-6807004 Negative regulation of MET activity 14/642 21/10654 5.693345973329289e-13 8.153433739582685e-12 3.8547540638135925e-12 7311/5795/867/9146/6455/7316/8027/6456/10254/6457/2060/7314/30011/6233 14 Gallid_herpesvirus_2 R-HSA-450341 Activation of the AP-1 family of transcription factors 10/642 10/10654 5.908344211634584e-13 8.358145470117216e-12 3.9515370144565065e-12 2353/1432/3725/1386/5601/5602/5599/5600/5594/5595 10 Gallid_herpesvirus_2 R-HSA-5099900 WNT5A-dependent internalization of FZD4 12/642 15/10654 7.995729318478936e-13 1.1174754228235621e-11 5.283164204093249e-12 409/163/1173/1213/1211/161/160/1175/1856/8322/1212/7474 12 Gallid_herpesvirus_2 R-HSA-3858494 Beta-catenin independent WNT signaling 35/642 146/10654 9.164943662730504e-13 1.2656350772342126e-11 5.983628631933074e-12 1857/27327/409/163/7311/1173/1213/387/1211/161/192670/54331/160/4343/2775/3845/5530/7316/1499/1175/26523/2782/4772/192669/1856/8322/23112/1212/5532/6934/57690/7314/6233/1855/7474 35 Gallid_herpesvirus_2 R-HSA-5655253 Signaling by FGFR2 in disease 19/642 43/10654 1.0413015341171743e-12 1.4210703289128495e-11 6.7184903934990436e-12 2962/2963/5437/5441/5434/5440/5290/5438/5431/5335/3845/5435/3265/5433/5439/2263/5430/5432/5436 19 Gallid_herpesvirus_2 R-HSA-9009391 Extra-nuclear estrogen signaling 25/642 77/10654 1.1883080709324592e-12 1.6028341421879684e-11 7.577827478039306e-12 1385/2353/4318/6464/1956/5290/54331/3320/3845/2100/4846/595/3265/1950/2782/2002/4314/2770/207/2771/2773/6714/2099/5594/5595 25 Gallid_herpesvirus_2 R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 13/642 19/10654 2.381335858601518e-12 3.13903363179291e-11 1.4840621798222383e-11 7311/867/6464/1956/5290/3320/5335/3845/7316/3265/1950/7314/6233 13 Gallid_herpesvirus_2 R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 13/642 19/10654 2.381335858601518e-12 3.13903363179291e-11 1.4840621798222383e-11 7311/867/6464/1956/5290/3320/5335/3845/7316/3265/1950/7314/6233 13 Gallid_herpesvirus_2 R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 26/642 86/10654 2.709569288250903e-12 3.531573454349491e-11 1.66964588903456e-11 10097/7409/10092/25/4067/60/5290/917/3320/5335/919/2534/51517/2214/10093/10109/6850/10552/695/10094/6714/5594/8976/5595/10096/3326 26 Gallid_herpesvirus_2 R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 16/642 31/10654 3.239420937217367e-12 4.1477842736154146e-11 1.9609760495042023e-11 1385/2353/6196/5598/1432/3725/4208/1386/5601/5602/5599/5600/2002/4205/5594/5595 16 Gallid_herpesvirus_2 R-HSA-5633007 Regulation of TP53 Activity 36/642 160/10654 3.253865249129334e-12 4.1477842736154146e-11 1.9609760495042023e-11 2475/672/5931/7311/7161/5928/6749/1432/57459/1616/6908/8851/5300/54815/2033/5600/7316/6872/890/1020/3065/3066/7157/53615/1107/1457/54971/9219/6874/207/641/5371/1108/7314/6233/4193 36 Gallid_herpesvirus_2 R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 14/642 23/10654 3.573027242339216e-12 4.505121305558142e-11 2.1299166970923704e-11 4089/7311/51592/7050/4088/7316/142/9611/3065/6497/9612/4087/7314/6233 14 Gallid_herpesvirus_2 R-HSA-1226099 Signaling by FGFR in disease 22/642 63/10654 5.158891699432762e-12 6.366291884406388e-11 3.009834910867267e-11 2962/2261/2963/5437/5441/5434/5440/5290/5438/5431/5335/3845/5435/3265/5433/5439/6774/2263/5430/5432/5436/6772 22 Gallid_herpesvirus_2 R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 22/642 63/10654 5.158891699432762e-12 6.366291884406388e-11 3.009834910867267e-11 3665/7311/1387/5437/5441/5434/5440/6778/4790/5591/2033/5435/7316/1499/3551/2547/1660/5970/4792/3661/7314/6233 22 Gallid_herpesvirus_2 R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 19/642 47/10654 7.21725472201393e-12 8.720849455766833e-11 4.1230150330803265e-11 10014/8850/7311/3091/1387/8841/2033/7316/55294/9734/9611/3065/3066/4851/9612/51564/4609/7314/6233 19 Gallid_herpesvirus_2 R-HSA-73762 RNA Polymerase I Transcription Initiation 19/642 47/10654 7.21725472201393e-12 8.720849455766833e-11 4.1230150330803265e-11 57504/5931/8850/5928/5437/5441/5434/5440/57459/6908/54815/5435/3065/3066/53615/9112/1107/9219/1108 19 Gallid_herpesvirus_2 R-HSA-913531 Interferon Signaling 40/642 199/10654 9.157163862595951e-12 1.0950835134650828e-10 5.177300458396626e-11 3665/7311/1958/3120/3123/5777/7341/3837/3838/3383/25820/3117/5300/3127/5335/3662/3115/960/7316/3122/3456/3458/3663/5781/3119/3664/567/3661/3105/4734/3660/5371/1974/3113/6772/3659/7314/6233/5595/8554 40 Gallid_herpesvirus_2 R-HSA-8934593 Regulation of RUNX1 Expression and Activity 12/642 17/10654 9.719234917955683e-12 1.1504400515131217e-10 5.439013310692708e-11 27327/192670/4343/595/26523/5781/192669/861/5371/23112/6714/57690 12 Gallid_herpesvirus_2 R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 22/642 65/10654 1.0596241394634239e-11 1.241579799775325e-10 5.869900868266283e-11 672/2962/2353/6749/3725/2963/5437/5441/5434/5440/1386/4436/5438/5431/5435/5433/5439/5430/7157/5432/5436/25920 22 Gallid_herpesvirus_2 R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 20/642 54/10654 1.3796546240630865e-11 1.6003993639131802e-10 7.566316411967033e-11 9318/7311/5437/5441/5434/5440/5438/5431/2033/5435/7316/5433/5439/10987/5430/5432/5436/7314/6233/10980 20 Gallid_herpesvirus_2 R-HSA-877300 Interferon gamma signaling 26/642 92/10654 1.5067381994079736e-11 1.730511199320049e-10 8.181454944153771e-11 3665/3120/3123/5777/7341/3383/3117/3127/3662/3115/960/3122/3458/3663/5781/3119/3664/567/3661/3105/3660/5371/3113/6772/3659/8554 26 Gallid_herpesvirus_2 R-HSA-162587 HIV Life Cycle 34/642 152/10654 1.568504865009682e-11 1.7837898464815993e-10 8.433344011042771e-11 2962/7311/5905/6749/2963/5437/5441/5434/5440/6908/7852/5438/7251/5431/5435/7316/3159/5433/6872/2547/2960/2961/5439/2959/5430/920/5432/6874/1234/5436/2957/7314/6233/25920 34 Gallid_herpesvirus_2 R-HSA-167172 Transcription of the HIV genome 23/642 73/10654 1.933158191148656e-11 2.1771490308081954e-10 1.0293054855272866e-10 2962/6749/2963/5437/5441/5434/5440/6908/5438/5431/5435/5433/6872/2960/2961/5439/2959/5430/5432/6874/5436/2957/25920 23 Gallid_herpesvirus_2 R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 16/642 34/10654 2.0030291559149344e-11 2.2128703055822133e-10 1.0461936744177253e-10 2962/6749/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/25920 16 Gallid_herpesvirus_2 R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 16/642 34/10654 2.0030291559149344e-11 2.2128703055822133e-10 1.0461936744177253e-10 2962/6749/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/25920 16 Gallid_herpesvirus_2 R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 21/642 61/10654 2.1641249045459306e-11 2.3682876313898867e-10 1.1196713756389572e-10 10097/7409/10092/25/60/917/3320/919/51517/2214/10093/10109/6850/10552/695/10094/5594/8976/5595/10096/3326 21 Gallid_herpesvirus_2 R-HSA-2219528 PI3K/AKT Signaling in Cancer 27/642 101/10654 2.547061188214939e-11 2.7612999797470365e-10 1.3054784840727822e-10 2475/7409/1385/941/2932/2261/3932/2064/6199/1956/5290/3667/2534/2100/5728/1950/842/5781/2263/1026/207/942/50852/6714/2099/940/4193 27 Gallid_herpesvirus_2 R-HSA-6804758 Regulation of TP53 Activity through Acetylation 15/642 30/10654 2.8434811792465714e-11 3.054109414746317e-10 1.4439119828337854e-10 5931/5928/57459/5300/54815/2033/3065/3066/7157/53615/1107/9219/207/5371/1108 15 Gallid_herpesvirus_2 R-HSA-432720 Lysosome Vesicle Biogenesis 16/642 35/10654 3.485899386672564e-11 3.7097644848992425e-10 1.7538904688135257e-10 6845/1213/164/351/1211/9146/4074/408/375/3312/9829/8673/6456/1212/1785/6844 16 Gallid_herpesvirus_2 R-HSA-167287 HIV elongation arrest and recovery 16/642 36/10654 5.927943258782145e-11 6.194967729898457e-10 2.928836830559979e-10 2962/6749/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/25920 16 Gallid_herpesvirus_2 R-HSA-167290 Pausing and recovery of HIV elongation 16/642 36/10654 5.927943258782145e-11 6.194967729898457e-10 2.928836830559979e-10 2962/6749/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/25920 16 Gallid_herpesvirus_2 R-HSA-164952 The role of Nef in HIV-1 replication and disease pathogenesis 14/642 27/10654 6.994651697847914e-11 7.117364885529456e-10 3.364924778004398e-10 163/1173/3932/164/161/160/919/2534/375/1175/920/567/926/940 14 Gallid_herpesvirus_2 R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 14/642 27/10654 6.994651697847914e-11 7.117364885529456e-10 3.364924778004398e-10 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 14 Gallid_herpesvirus_2 R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 14/642 27/10654 6.994651697847914e-11 7.117364885529456e-10 3.364924778004398e-10 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 14 Gallid_herpesvirus_2 R-HSA-202424 Downstream TCR signaling 26/642 98/10654 7.192991744371433e-11 7.255539498670315e-10 3.4302505252334246e-10 7311/3120/3123/3932/915/3117/5588/5290/917/3127/4790/919/3115/7316/5728/3122/3551/916/3119/920/5970/4792/50852/3113/7314/6233 26 Gallid_herpesvirus_2 R-HSA-6783783 Interleukin-10 signaling 18/642 47/10654 7.631663946241137e-11 7.631663946241137e-10 3.608073426489685e-10 7124/5743/3552/941/6347/3383/3576/2920/6352/6351/6774/3569/1234/942/3586/3606/3553/2919 18 Gallid_herpesvirus_2 R-HSA-6806834 Signaling by MET 23/642 79/10654 1.173255979941109e-10 1.1632281510527234e-9 5.499472474577758e-10 7311/5795/867/6464/5290/9146/6455/2335/3845/7316/3265/5781/8027/6774/6456/10048/10254/6457/2060/6714/7314/30011/6233 23 Gallid_herpesvirus_2 R-HSA-1980143 Signaling by NOTCH1 22/642 73/10654 1.4144010511658837e-10 1.3904281519935807e-9 6.57362129935259e-10 10014/409/8850/7311/3091/1387/8841/2033/408/7316/55294/9734/9611/3065/3066/4851/83737/9612/51564/4609/7314/6233 22 Gallid_herpesvirus_2 R-HSA-113418 Formation of the Early Elongation Complex 15/642 33/10654 1.6038752730465822e-10 1.5375994353173847e-9 7.269412938297255e-10 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/25920 15 Gallid_herpesvirus_2 R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 15/642 33/10654 1.6038752730465822e-10 1.5375994353173847e-9 7.269412938297255e-10 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/25920 15 Gallid_herpesvirus_2 R-HSA-1839126 FGFR2 mutant receptor activation 15/642 33/10654 1.6038752730465822e-10 1.5375994353173847e-9 7.269412938297255e-10 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/2263/5430/5432/5436 15 Gallid_herpesvirus_2 R-HSA-164938 Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 12/642 20/10654 1.6720609296624638e-10 1.5898284249249656e-9 7.51633946811168e-10 163/1173/3932/164/161/160/375/1175/920/567/926/940 12 Gallid_herpesvirus_2 R-HSA-6807505 RNA polymerase II transcribes snRNA genes 22/642 74/10654 1.900742788391033e-10 1.7925704345801613e-9 8.474856591799129e-10 2962/2963/5437/5441/5434/5440/6908/5438/5431/5435/55197/5433/2960/2961/5439/2959/5430/5432/5436/5451/6667/2957 22 Gallid_herpesvirus_2 R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 17/642 44/10654 2.1934918385156277e-10 2.0519762360307486e-9 9.701266959818695e-10 4089/7311/51592/3726/7050/4088/7316/142/9611/3065/6497/9612/4087/6667/4609/7314/6233 17 Gallid_herpesvirus_2 R-HSA-72086 mRNA Capping 14/642 29/10654 2.415525127846296e-10 2.2416073186413626e-9 1.0597798666171962e-9 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 14 Gallid_herpesvirus_2 R-HSA-1227986 Signaling by ERBB2 18/642 50/10654 2.541514919664762e-10 2.3398073863580344e-9 1.1062065773979457e-9 7311/2064/387/6464/1956/5290/3320/5335/3845/2534/7316/3265/1950/10273/207/6714/7314/6233 18 Gallid_herpesvirus_2 R-HSA-5696398 Nucleotide Excision Repair 27/642 111/10654 2.677434622670031e-10 2.4455308364545165e-9 1.15619016859601e-9 9318/7311/7341/5437/5441/5434/5440/3980/60/5438/5431/2033/5435/7316/142/5433/5439/10987/5430/5432/5436/7329/7314/6233/8554/10980/7528 27 Gallid_herpesvirus_2 R-HSA-1643713 Signaling by EGFR in Cancer 13/642 25/10654 3.2549661232200166e-10 2.94981304916814e-9 1.3946030840441026e-009 7311/867/6464/1956/5290/3320/5335/3845/7316/3265/1950/7314/6233 13 Gallid_herpesvirus_2 R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 23/642 84/10654 4.5712469957269625e-10 4.078958857725597e-9 1.928436991719634e-9 7124/1051/1387/23054/1019/8841/6604/7040/688/4790/5465/2033/5468/9611/5469/8202/1050/5970/8648/9612/1959/10498/4023 23 Gallid_herpesvirus_2 R-HSA-674695 RNA Polymerase II Pre-transcription Events 23/642 84/10654 4.5712469957269625e-10 4.078958857725597e-9 1.928436991719634e-9 2962/6749/2963/5437/5441/5434/5440/6908/5438/5431/5435/5433/6872/2960/2961/5439/2959/5430/5432/6874/5436/2957/25920 23 Gallid_herpesvirus_2 R-HSA-196025 Formation of annular gap junctions 9/642 11/10654 4.895612294381394e-10 4.335046001131616e-9 2.049509044092171e-9 1173/1759/1213/1211/60/8218/1212/1601/1785 9 Gallid_herpesvirus_2 R-HSA-168254 Influenza Infection 32/642 155/10654 5.614302152384425e-10 4.93378067936813e-9 2.332576891062429e-9 2962/7311/6204/6223/6146/6141/2963/3837/3838/5437/6203/1213/5441/5434/5440/1211/3921/6206/7040/5438/3320/5431/5435/6175/5433/6129/5439/5430/5432/5436/6176/6233 32 Gallid_herpesvirus_2 R-HSA-5683057 MAPK family signaling cascades 47/642 294/10654 5.756138942690974e-10 5.020391859790624e-9 2.373524645146021e-9 27327/409/7311/2118/3725/2261/27040/2064/3558/6464/1956/60/192670/3667/1843/4343/2335/3845/2534/408/7316/5604/3265/1950/3559/26523/1445/5781/192669/5567/8202/3569/2263/5597/10048/1847/5245/23112/6714/57690/5594/4609/7314/6233/5568/5595/5566 47 Gallid_herpesvirus_2 R-HSA-3928662 EPHB-mediated forward signaling 16/642 42/10654 9.605710251201685e-10 8.31539096372683e-9 3.931323677043267e-9 10097/10092/4067/6383/387/60/2534/6453/3265/10093/10109/10552/10094/6714/8976/10096 16 Gallid_herpesvirus_2 R-HSA-170834 Signaling by TGF-beta Receptor Complex 21/642 73/10654 9.701006399924885e-10 8.335679573268791e-9 3.940915660320363e-9 4089/7311/51592/867/3726/7050/387/4088/7040/7316/142/9611/3065/6497/9612/10273/4087/6667/4609/7314/6233 21 Gallid_herpesvirus_2 R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 17/642 48/10654 1.0803010462218244e-9 9.131071397926037e-9 4.316958437676466e-9 7409/7311/5777/867/3558/4067/6464/3636/5290/2534/7316/3559/5781/6850/7314/6233/5566 17 Gallid_herpesvirus_2 R-HSA-8848021 Signaling by PTK6 18/642 54/10654 1.0862826318222355e-9 9.131071397926037e-9 4.316958437676466e-9 7311/3091/867/2064/2034/1019/387/1956/2908/3845/7316/595/3265/1950/6774/207/7314/6233 18 Gallid_herpesvirus_2 R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 18/642 54/10654 1.0862826318222355e-9 9.131071397926037e-9 4.316958437676466e-9 7311/3091/867/2064/2034/1019/387/1956/2908/3845/7316/595/3265/1950/6774/207/7314/6233 18 Gallid_herpesvirus_2 R-HSA-168255 Influenza Life Cycle 30/642 144/10654 1.5545753251877737e-9 1.2973434368473506e-8 6.133538390176676e-9 2962/7311/6204/6223/6146/6141/2963/3837/5437/6203/1213/5441/5434/5440/1211/3921/6206/5438/3320/5431/5435/6175/5433/6129/5439/5430/5432/5436/6176/6233 30 Gallid_herpesvirus_2 R-HSA-190873 Gap junction degradation 9/642 12/10654 1.8535458537372293e-9 1.5357951359537043e-8 7.260882630053357e-9 1173/1759/1213/1211/60/8218/1212/1601/1785 9 Gallid_herpesvirus_2 R-HSA-8986944 Transcriptional Regulation by MECP2 19/642 62/10654 1.881789696990058e-9 1.548139041495367e-8 7.319241747904593e-9 27327/1385/4208/627/8841/6657/192670/4343/5728/5468/9611/26523/192669/3065/3066/9612/23112/57690/5566 19 Gallid_herpesvirus_2 R-HSA-9022692 Regulation of MECP2 expression and activity 14/642 33/10654 2.0344248230468276e-9 1.6619245033340282e-8 7.85719297855743e-9 27327/1385/8841/192670/4343/9611/26523/192669/3065/3066/9612/23112/57690/5566 14 Gallid_herpesvirus_2 R-HSA-8878166 Transcriptional regulation by RUNX2 27/642 121/10654 2.1101323605104778e-9 1.7117157609735344e-8 8.09259447792388e-9 4089/5925/7311/367/2932/860/25/1019/8841/2908/7316/595/55294/4094/23314/861/1026/10273/207/10413/6772/6714/2099/5594/7314/6233/5595 27 Gallid_herpesvirus_2 R-HSA-162599 Late Phase of HIV Life Cycle 29/642 139/10654 2.8197628980190876e-9 2.2714756678487092e-8 1.0739009282660416e-8 2962/7311/5905/6749/2963/5437/5441/5434/5440/6908/5438/7251/5431/5435/7316/5433/6872/2960/2961/5439/2959/5430/5432/6874/5436/2957/7314/6233/25920 29 Gallid_herpesvirus_2 R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 13/642 29/10654 3.391518532516793e-9 2.7132148260134345e-8 1.2827449404292191e-8 5437/5441/5434/5440/5438/3320/5431/5435/5433/5439/5430/5432/5436 13 Gallid_herpesvirus_2 R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 18/642 58/10654 4.015157324629373e-9 3.1050549977133816e-8 1.4679978709697564e-8 10014/8850/7311/1387/8841/2033/7316/55294/9734/9611/3065/3066/4851/9612/51564/4609/7314/6233 18 Gallid_herpesvirus_2 R-HSA-2644603 Signaling by NOTCH1 in Cancer 18/642 58/10654 4.015157324629373e-9 3.1050549977133816e-8 1.4679978709697564e-8 10014/8850/7311/1387/8841/2033/7316/55294/9734/9611/3065/3066/4851/9612/51564/4609/7314/6233 18 Gallid_herpesvirus_2 R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 18/642 58/10654 4.015157324629373e-9 3.1050549977133816e-8 1.4679978709697564e-8 10014/8850/7311/1387/8841/2033/7316/55294/9734/9611/3065/3066/4851/9612/51564/4609/7314/6233 18 Gallid_herpesvirus_2 R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 18/642 58/10654 4.015157324629373e-9 3.1050549977133816e-8 1.4679978709697564e-8 10014/8850/7311/1387/8841/2033/7316/55294/9734/9611/3065/3066/4851/9612/51564/4609/7314/6233 18 Gallid_herpesvirus_2 R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 18/642 58/10654 4.015157324629373e-9 3.1050549977133816e-8 1.4679978709697564e-8 10014/8850/7311/1387/8841/2033/7316/55294/9734/9611/3065/3066/4851/9612/51564/4609/7314/6233 18 Gallid_herpesvirus_2 R-HSA-5654741 Signaling by FGFR3 15/642 40/10654 4.184346725860982e-9 3.214465034436251e-8 1.5197243946835635e-8 7311/2261/867/6464/5290/5335/3845/7316/3265/5781/6714/5594/7314/6233/5595 15 Gallid_herpesvirus_2 R-HSA-167169 HIV Transcription Elongation 16/642 46/10654 4.557992602335116e-9 3.4148235370618917e-8 1.614449240298771e-8 2962/6749/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/25920 16 Gallid_herpesvirus_2 R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 16/642 46/10654 4.557992602335116e-9 3.4148235370618917e-8 1.614449240298771e-8 2962/6749/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/25920 16 Gallid_herpesvirus_2 R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 16/642 46/10654 4.557992602335116e-9 3.4148235370618917e-8 1.614449240298771e-8 2962/6749/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/25920 16 Gallid_herpesvirus_2 R-HSA-9614085 FOXO-mediated transcription 19/642 65/10654 4.562910760729252e-9 3.4148235370618917e-8 1.614449240298771e-8 4089/8850/604/1387/23411/4088/1649/2908/2033/10018/3630/3065/3066/356/4800/6648/1026/207/4087 19 Gallid_herpesvirus_2 R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 21/642 79/10654 4.726824533370969e-9 3.5148182427630284e-8 1.6617244142282557e-8 9318/7311/5437/5441/5434/5440/3980/5438/5431/2033/5435/7316/5433/5439/10987/5430/5432/5436/7314/6233/10980 21 Gallid_herpesvirus_2 R-HSA-2424491 DAP12 signaling 13/642 30/10654 5.657715262383389e-9 4.160026281033624e-8 1.9667637862237005e-8 27040/3932/9402/6464/5290/5335/3845/2534/3265/3937/567/6850/695 13 Gallid_herpesvirus_2 R-HSA-209560 NF-kB is activated and signals survival 9/642 13/10654 5.702104988658157e-9 4.160026281033624e-8 1.9667637862237005e-8 7311/4790/7316/4803/3551/5970/4792/7314/6233 9 Gallid_herpesvirus_2 R-HSA-5140745 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 9/642 13/10654 5.702104988658157e-9 4.160026281033624e-8 1.9667637862237005e-8 163/1173/1213/1211/161/160/1175/1212/7474 9 Gallid_herpesvirus_2 R-HSA-157118 Signaling by NOTCH 39/642 235/10654 5.995102543379651e-9 4.346449343950247e-8 2.054900279671578e-8 10014/27327/409/1385/8850/7311/3091/3725/1387/1956/4088/8841/192670/4343/2033/408/7316/595/55294/1950/9734/9611/26523/192669/3065/3066/4851/7157/83737/9612/861/207/51564/23112/6772/57690/4609/7314/6233 39 Gallid_herpesvirus_2 R-HSA-5621575 CD209 (DC-SIGN) signaling 11/642 21/10654 7.082468315052824e-9 5.1028964257523455e-8 2.412530887311227e-8 1387/4067/4790/3845/2534/2033/3265/5567/5970/5568/5566 11 Gallid_herpesvirus_2 R-HSA-4655427 SUMOylation of DNA methylation proteins 10/642 17/10654 7.79569094971154e-9 5.557563609191893e-8 2.627486969499978e-8 1912/80012/7341/84733/57332/8535/1911/7329/6045/6015 10 Gallid_herpesvirus_2 R-HSA-8878159 Transcriptional regulation by RUNX3 23/642 96/10654 7.809335071536884e-9 5.557563609191893e-8 2.627486969499978e-8 4089/8850/7311/1387/4088/7040/3845/2033/7316/595/1499/10018/4851/7157/861/1026/10413/6714/6934/4609/7314/6233/4193 23 Gallid_herpesvirus_2 R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 14/642 36/10654 7.963107739557239e-9 5.6324420596868275e-8 2.6628877614308865e-8 10097/10092/25/60/51517/10093/10109/10552/695/10094/5594/8976/5595/10096 14 Gallid_herpesvirus_2 R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 16/642 48/10654 9.253831596900558e-9 6.505724031760392e-8 3.075755191059134e-8 2962/6749/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/25920 16 Gallid_herpesvirus_2 R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 14/642 37/10654 1.2107514875761817e-8 8.460673045713078e-8 4.000009670432408e-8 27327/8841/192670/4343/2033/9611/26523/192669/8648/9612/23028/23112/57690/10062 14 Gallid_herpesvirus_2 R-HSA-4086398 Ca2+ pathway 18/642 62/10654 1.3138229022282459e-8 9.125955488531528e-8 4.3145397545598245e-8 27327/192670/54331/4343/2775/3845/5530/1499/26523/2782/4772/192669/8322/23112/5532/6934/57690/7474 18 Gallid_herpesvirus_2 R-HSA-1433557 Signaling by SCF-KIT 15/642 43/10654 1.330157301252396e-8 9.184419461028449e-8 4.342180162609639e-8 7409/5777/867/3932/4318/9402/4067/5290/3845/2534/3265/5781/6774/6772/6714 15 Gallid_herpesvirus_2 R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 14/642 38/10654 1.811887977282658e-8 1.243662753637801e-7 5.87974859024768e-8 7020/7341/1387/2064/1956/2033/1026/7329/7422/2099/4609/3329/7528/4869 14 Gallid_herpesvirus_2 R-HSA-168273 Influenza Viral RNA Transcription and Replication 27/642 134/10654 2.1840165725304124e-8 1.4902701318442813e-7 7.045650986305541e-8 2962/7311/6204/6223/6146/6141/2963/5437/6203/5441/5434/5440/3921/6206/5438/3320/5431/5435/6175/5433/6129/5439/5430/5432/5436/6176/6233 27 Gallid_herpesvirus_2 R-HSA-195721 Signaling by WNT 47/642 331/10654 2.8623361724060913e-8 1.9417017309889275e-7 9.17991471728885e-8 1857/27327/409/163/7311/9070/2932/1173/1387/1213/387/1211/161/6657/192670/54331/160/4343/2775/3845/2033/5530/6597/7316/1499/1175/26523/2782/4772/192669/3065/1856/1457/207/8085/8322/23112/1212/5532/6934/57690/4609/7314/6233/1855/7474/5929 47 Gallid_herpesvirus_2 R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 18/642 65/10654 2.983546757900333e-8 2.0121594413746432e-7 9.513022404321134e-8 7311/5437/5441/5434/5440/3980/5438/5431/2033/5435/7316/5433/5439/5430/5432/5436/7314/6233 18 Gallid_herpesvirus_2 R-HSA-8964038 LDL clearance 10/642 19/10654 3.3151269339065204e-8 2.2228596782263374e-7 1.0509164177458456e-7 163/3949/1173/1213/1211/161/160/338/26119/1175 10 Gallid_herpesvirus_2 R-HSA-5637810 Constitutive Signaling by EGFRvIII 9/642 15/10654 3.576575058376068e-8 2.3707583244092795e-7 1.1208394619031167e-7 867/6464/1956/5290/3320/5335/3845/3265/1950 9 Gallid_herpesvirus_2 R-HSA-5637812 Signaling by EGFRvIII in Cancer 9/642 15/10654 3.576575058376068e-8 2.3707583244092795e-7 1.1208394619031167e-7 867/6464/1956/5290/3320/5335/3845/3265/1950 9 Gallid_herpesvirus_2 R-HSA-8940973 RUNX2 regulates osteoblast differentiation 11/642 24/10654 4.2412879218066755e-8 2.795394312099854e-7 1.321597492381147e-7 5925/367/860/25/8841/4094/23314/10413/6714/5594/5595 11 Gallid_herpesvirus_2 R-HSA-437239 Recycling pathway of L1 15/642 47/10654 5.262003834638162e-8 3.4291710383035214e-7 1.6212324055863292e-7 163/6196/1173/1759/1213/1211/161/60/160/1175/6456/6714/5594/26052/1785 15 Gallid_herpesvirus_2 R-HSA-9024446 NR1H2 and NR1H3-mediated signaling 15/642 47/10654 5.262003834638162e-8 3.4291710383035214e-7 1.6212324055863292e-7 27327/8841/192670/4343/2033/9611/26523/8204/192669/8648/9612/23028/23112/57690/10062 15 Gallid_herpesvirus_2 R-HSA-5654743 Signaling by FGFR4 14/642 41/10654 5.575808164622243e-8 3.613372888805476e-7 1.7083187614044042e-7 7311/867/6464/5290/5335/3845/7316/3265/5781/6714/5594/7314/6233/5595 14 Gallid_herpesvirus_2 R-HSA-5250913 Positive epigenetic regulation of rRNA expression 23/642 106/10654 5.7687409383970775e-8 3.7176330491892276e-7 1.7576105432192265e-7 57504/5931/8850/5928/2932/5437/5441/5434/5440/57459/6908/60/54815/2033/5435/3065/3066/53615/9112/1107/9219/1108/9188 23 Gallid_herpesvirus_2 R-HSA-212165 Epigenetic regulation of gene expression 28/642 149/10654 5.848595062765667e-8 3.748270868954792e-7 1.7720953926728191e-7 57504/5931/8850/5928/2932/29947/5437/5441/5434/5440/57459/6908/23411/60/8726/54815/2033/23512/5435/2146/3065/3066/53615/9112/1107/9219/1108/9188 28 Gallid_herpesvirus_2 R-HSA-4090294 SUMOylation of intracellular receptors 12/642 30/10654 6.558003355607795e-8 4.1798263145632095e-7 1.9761247821120075e-7 367/7341/9063/2516/2908/5465/5468/7421/7329/2099/10062/8554 12 Gallid_herpesvirus_2 R-HSA-8866427 VLDLR internalisation and degradation 8/642 12/10654 6.645349272097483e-8 4.2123525440617927e-7 1.9915024278186878e-7 163/1173/1213/1211/161/160/1175/10062 8 Gallid_herpesvirus_2 R-HSA-4420097 VEGFA-VEGFR2 Pathway 22/642 99/10654 7.123326004260667e-8 4.4907924809469423e-7 2.1231423616818124e-7 2475/7409/1432/387/60/5290/3320/5335/3845/2534/5600/4846/1499/3265/6300/5603/5567/207/7422/6714/5568/5566 22 Gallid_herpesvirus_2 R-HSA-9006115 Signaling by NTRK2 (TRKB) 11/642 25/10654 7.163911985436396e-8 4.4919664341114696e-7 2.1236973794664936e-7 627/6464/8851/5290/5335/3845/2534/3265/1020/5781/6714 11 Gallid_herpesvirus_2 R-HSA-1295596 Spry regulation of FGF signaling 9/642 16/10654 7.738826681807206e-8 4.775020718561893e-7 2.2575188696649244e-7 7311/867/7316/5781/6714/5594/7314/6233/5595 9 Gallid_herpesvirus_2 R-HSA-193639 p75NTR signals via NF-kB 9/642 16/10654 7.738826681807206e-8 4.775020718561893e-7 2.2575188696649244e-7 7311/4790/7316/4803/3551/5970/4792/7314/6233 9 Gallid_herpesvirus_2 R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 9/642 16/10654 7.738826681807206e-8 4.775020718561893e-7 2.2575188696649244e-7 7311/4790/7316/5604/3551/79155/6416/7314/6233 9 Gallid_herpesvirus_2 R-HSA-5621481 C-type lectin receptors (CLRs) 27/642 142/10654 7.826182718180702e-8 4.803371403751118e-7 2.2709224150220806e-7 7311/1387/4067/4773/4790/3845/2534/2033/5530/7316/3265/3551/4772/5567/5970/4792/6850/2207/3553/5532/6714/7314/6233/5568/4775/4582/5566 27 Gallid_herpesvirus_2 R-HSA-1989781 PPARA activates gene expression 24/642 117/10654 9.294101992446165e-8 5.674293848019764e-7 2.6826743147171477e-7 1387/23054/8841/6604/1374/5465/2033/406/5468/335/9611/5469/405/51/8202/8648/4800/9612/4199/6667/2168/336/10062/10498 24 Gallid_herpesvirus_2 R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 16/642 56/10654 1.0860657186620675e-7 6.596001223287949e-7 3.1184361500299654e-7 1385/4208/1387/23054/1386/8841/6604/5465/4209/9611/5469/23373/8648/6648/54205/10498 16 Gallid_herpesvirus_2 R-HSA-168325 Viral Messenger RNA Synthesis 14/642 43/10654 1.1079696563038056e-7 6.693983340168825e-7 3.1647598187186554e-7 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 14 Gallid_herpesvirus_2 R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 19/642 78/10654 1.1847008809956817e-7 7.115852637355275e-7 3.3642098221979113e-7 3665/7311/1387/351/5300/7186/4790/2033/7316/3551/3456/5970/4792/83737/3661/7314/6233/3146/4214 19 Gallid_herpesvirus_2 R-HSA-199418 Negative regulation of the PI3K/AKT network 23/642 110/10654 1.1900650100404512e-7 7.115852637355275e-7 3.3642098221979113e-7 7409/941/2261/3932/2064/1956/5290/3667/2534/2100/5728/1950/5781/3630/2263/207/942/50852/6714/2099/5594/940/5595 23 Gallid_herpesvirus_2 R-HSA-76002 Platelet activation, signaling and aggregation 39/642 262/10654 1.2699611219683213e-7 7.554640520426937e-7 3.5716585400566555e-7 7409/409/1432/5777/27040/3932/3479/4067/334/351/387/6464/5588/5290/54331/7040/7018/2335/2534/408/7042/1950/335/1445/2782/5781/3937/2770/6850/207/7043/2207/7422/2771/2773/6714/5594/5595/3700 39 Gallid_herpesvirus_2 R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 24/642 119/10654 1.3032909337625036e-7 7.713354505941348e-7 3.646694825404213e-7 1387/23054/8841/6604/1374/5465/2033/406/5468/335/9611/5469/405/51/8202/8648/4800/9612/4199/6667/2168/336/10062/10498 24 Gallid_herpesvirus_2 R-HSA-4551638 SUMOylation of chromatin organization proteins 18/642 71/10654 1.3229928848129185e-7 7.79021191057353e-7 3.6830312208791374e-7 1912/80012/7341/84733/9063/23512/57332/3065/3066/23314/1107/8535/1911/6304/7329/6045/6015/8554 18 Gallid_herpesvirus_2 R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 22/642 103/10654 1.5059862769049073e-7 8.822949905099457e-7 4.171285753681322e-7 7409/941/2261/3932/2064/1956/5290/3667/2534/2100/1950/5781/3630/2263/207/942/50852/6714/2099/5594/940/5595 22 Gallid_herpesvirus_2 R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 12/642 32/10654 1.5309110188376644e-7 8.879283909258453e-7 4.1979191621811743e-7 4089/7311/3726/7050/4088/7316/3065/4087/6667/4609/7314/6233 12 Gallid_herpesvirus_2 R-HSA-8941326 RUNX2 regulates bone development 12/642 32/10654 1.5309110188376644e-7 8.879283909258453e-7 4.1979191621811743e-7 4089/5925/367/860/25/8841/4094/23314/10413/6714/5594/5595 12 Gallid_herpesvirus_2 R-HSA-3928665 EPH-ephrin mediated repulsion of cells 15/642 51/10654 1.7807465595751921e-7 1.0276945318941408e-6 4.858701008319849e-7 163/1173/4318/1759/1213/4067/1211/161/60/160/2534/1175/8218/1212/6714 15 Gallid_herpesvirus_2 R-HSA-1236394 Signaling by ERBB4 16/642 58/10654 1.8617908651126023e-7 1.0691472294706032e-6 5.054679732796591e-7 7311/6464/1956/5290/3845/7316/3265/1950/9611/83737/4734/10413/6714/2099/7314/6233 16 Gallid_herpesvirus_2 R-HSA-912631 Regulation of signaling by CBL 10/642 22/10654 1.966096778147654e-7 1.1234838732272307e-6 5.311570761809322e-7 7409/7311/867/4067/5290/2534/7316/6850/7314/6233 10 Gallid_herpesvirus_2 R-HSA-389356 CD28 co-stimulation 12/642 33/10654 2.2749997908907867e-7 1.2873169548455183e-6 6.086135512472914e-7 2475/7409/941/3932/9402/4067/5290/2534/207/942/6714/940 12 Gallid_herpesvirus_2 R-HSA-8964043 Plasma lipoprotein clearance 12/642 33/10654 2.2749997908907867e-7 1.2873169548455183e-6 6.086135512472914e-7 163/3949/1173/1213/1211/161/160/338/26119/1175/335/10062 12 Gallid_herpesvirus_2 R-HSA-6782135 Dual incision in TC-NER 17/642 66/10654 2.3026988391519346e-7 1.296665365736041e-6 6.130332627481645e-7 7311/5437/5441/5434/5440/5438/5431/2033/5435/7316/5433/5439/5430/5432/5436/7314/6233 17 Gallid_herpesvirus_2 R-HSA-383280 Nuclear Receptor transcription pathway 15/642 52/10654 2.3652421318346002e-7 1.3254496970667324e-6 6.26641825927194e-7 367/2516/2908/5465/2100/5468/3172/9611/5469/2063/9612/7421/2099/10062/7101 15 Gallid_herpesvirus_2 R-HSA-350054 Notch-HLH transcription pathway 11/642 28/10654 2.9211973236394357e-7 1.628218299409893e-6 7.697837876520456e-7 10014/8850/1387/8841/9734/9611/3065/3066/4851/9612/51564 11 Gallid_herpesvirus_2 R-HSA-1368082 RORA activates gene expression 9/642 18/10654 2.9476365765179096e-7 1.628218299409893e-6 7.697837876520456e-7 1387/23054/6604/1374/5465/2033/5469/8648/10498 9 Gallid_herpesvirus_2 R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 9/642 18/10654 2.9476365765179096e-7 1.628218299409893e-6 7.697837876520456e-7 1385/6196/5598/1956/3845/3265/4314/5594/5595 9 Gallid_herpesvirus_2 R-HSA-194138 Signaling by VEGF 22/642 107/10654 3.053880885755598e-7 1.6789108187092387e-6 7.937500331647128e-7 2475/7409/1432/387/60/5290/3320/5335/3845/2534/5600/4846/1499/3265/6300/5603/5567/207/7422/6714/5568/5566 22 Gallid_herpesvirus_2 R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 18/642 75/10654 3.2427977064756643e-7 1.7743610092036655e-6 8.388766658757802e-7 7409/941/2261/3932/2064/1956/5290/3667/2534/2100/1950/5781/2263/942/50852/6714/2099/940 18 Gallid_herpesvirus_2 R-HSA-187687 Signalling to ERKs 12/642 34/10654 3.324927893929504e-7 1.8107588530320304e-6 8.560847208980833e-7 1432/6464/3845/5600/5604/4803/3265/6300/5603/6714/5594/5595 12 Gallid_herpesvirus_2 R-HSA-112382 Formation of RNA Pol II elongation complex 16/642 61/10654 3.984480785524476e-7 2.1497663773062287e-6 1.0163596030640156e-6 2962/6749/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/25920 16 Gallid_herpesvirus_2 R-HSA-75955 RNA Polymerase II Transcription Elongation 16/642 61/10654 3.984480785524476e-7 2.1497663773062287e-6 1.0163596030640156e-6 2962/6749/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/25920 16 Gallid_herpesvirus_2 R-HSA-174824 Plasma lipoprotein assembly, remodeling, and clearance 17/642 69/10654 4.60483350831554e-7 2.4729661433546417e-6 1.1691609443627662e-6 163/3949/1173/1213/1211/161/160/338/26119/1175/335/5567/336/10062/4023/5568/5566 17 Gallid_herpesvirus_2 R-HSA-114604 GPVI-mediated activation cascade 12/642 35/10654 4.784923715914774e-7 2.55783940574246e-6 1.2092870511722517e-6 7409/5777/27040/3932/4067/387/5290/2534/5781/3937/6850/2207 12 Gallid_herpesvirus_2 R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 15/642 55/10654 5.302083165431955e-7 2.8212919595876458e-6 1.3338412984983333e-6 7311/1432/351/4790/5600/7316/3551/6300/842/5603/5970/83737/7314/6233/3326 15 Gallid_herpesvirus_2 R-HSA-9006936 Signaling by TGF-beta family members 21/642 102/10654 5.535773669461005e-7 2.932190619440532e-6 1.3862716086465677e-6 4089/7311/51592/867/3726/7050/387/4088/7040/7316/142/9611/3065/6497/9612/10273/4087/6667/4609/7314/6233 21 Gallid_herpesvirus_2 R-HSA-983705 Signaling by the B Cell Receptor (BCR) 22/642 112/10654 7.005480168790087e-7 3.6937986344529547e-6 1.7463421856170505e-6 7409/7311/5777/4067/4773/4790/3845/2534/5530/7316/3265/3551/4772/5970/4792/6850/695/5532/7314/30011/6233/4775 22 Gallid_herpesvirus_2 R-HSA-1592230 Mitochondrial biogenesis 20/642 95/10654 7.06814801736175e-7 3.7099781448595614e-6 1.753991482279339e-6 1385/1432/4208/1387/23054/1386/8841/6604/8834/5465/4209/5600/9611/5469/6300/23373/8648/6648/54205/10498 20 Gallid_herpesvirus_2 R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 7/642 11/10654 7.452107297260306e-7 3.893893903072953e-6 1.8409425803094452e-6 3091/1387/2034/2033/405/7422/2056 7 Gallid_herpesvirus_2 R-HSA-2172127 DAP12 interactions 13/642 43/10654 8.329035402491857e-7 4.332592406677379e-6 2.0483490416324086e-6 27040/3932/9402/6464/5290/5335/3845/2534/3265/3937/567/6850/695 13 Gallid_herpesvirus_2 R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 10/642 25/10654 8.422191670107489e-7 4.361492114877093e-6 2.0620121523148506e-6 1385/6196/5598/1432/4208/5600/2002/4205/5594/5595 10 Gallid_herpesvirus_2 R-HSA-5654736 Signaling by FGFR1 14/642 50/10654 8.940233335167108e-7 4.609186963908376e-6 2.1791165228641236e-6 7311/867/6464/5290/5335/3845/7316/3265/5781/6714/5594/7314/6233/5595 14 Gallid_herpesvirus_2 R-HSA-167044 Signalling to RAS 9/642 20/10654 9.126968821441988e-7 4.684638864102967e-6 2.2147884284915115e-6 1432/6464/3845/5600/4803/3265/6300/5603/6714 9 Gallid_herpesvirus_2 R-HSA-5687128 MAPK6/MAPK4 signaling 19/642 89/10654 1.0689540311320805e-6 5.46249637054279e-6 2.5825413875252216e-6 27327/7311/2118/3725/192670/4343/7316/26523/192669/5567/8202/5597/23112/57690/4609/7314/6233/5568/5566 19 Gallid_herpesvirus_2 R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 8/642 16/10654 1.3910579038032036e-6 7.07731214215665e-6 3.3459887713825906e-6 4067/2206/6464/5290/2205/2534/6850/2207 8 Gallid_herpesvirus_2 R-HSA-72165 mRNA Splicing - Minor Pathway 14/642 52/10654 1.5069644299574602e-6 7.633531610264864e-6 3.6089564146533523e-6 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 14 Gallid_herpesvirus_2 R-HSA-2029481 FCGR activation 7/642 12/10654 1.6954708615331107e-6 8.51405281116194e-6 4.025246383498522e-6 4067/917/919/2534/2214/6850/6714 7 Gallid_herpesvirus_2 R-HSA-210990 PECAM1 interactions 7/642 12/10654 1.6954708615331107e-6 8.51405281116194e-6 4.025246383498522e-6 5777/3932/4067/5335/2534/5781/6714 7 Gallid_herpesvirus_2 R-HSA-4086400 PCP/CE pathway 19/642 92/10654 1.8197726302253406e-6 9.059812236315001e-6 4.2832687614520105e-6 1857/409/163/7311/1173/1213/387/1211/161/160/7316/1175/1856/8322/1212/7314/6233/1855/7474 19 Gallid_herpesvirus_2 R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 19/642 92/10654 1.8197726302253406e-6 9.059812236315001e-6 4.2832687614520105e-6 672/7311/6749/1432/6908/8851/5300/5600/7316/6872/890/1020/7157/1457/6874/641/7314/6233/4193 19 Gallid_herpesvirus_2 R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 21/642 110/10654 2.0347229668959223e-6 1.008666086153534e-5 4.768738937259449e-6 2353/6196/7311/5598/3552/3725/1051/1019/3576/3490/4790/7316/890/6774/3569/5970/1026/5594/7314/6233/5595 21 Gallid_herpesvirus_2 R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 17/642 77/10654 2.406466948495176e-6 1.1859549849463139e-5 5.606919665671775e-6 672/1912/80012/7341/84733/9063/57332/142/8535/1911/51564/7329/6045/641/5371/6015/8554 17 Gallid_herpesvirus_2 R-HSA-198753 ERK/MAPK targets 9/642 22/10654 2.423028719243762e-6 1.1859549849463139e-5 5.606919665671775e-6 6196/5598/1432/4208/5600/2002/4205/5594/5595 9 Gallid_herpesvirus_2 R-HSA-9613829 Chaperone Mediated Autophagy 9/642 22/10654 2.423028719243762e-6 1.1859549849463139e-5 5.606919665671775e-6 1080/7311/3320/7431/7316/3312/7314/6233/3326 9 Gallid_herpesvirus_2 R-HSA-9034015 Signaling by NTRK3 (TRKC) 8/642 17/10654 2.489171671921617e-6 1.2132097224491912e-5 5.7357737331763045e-6 6464/5290/3667/5335/3845/3265/6714/25920 8 Gallid_herpesvirus_2 R-HSA-3214815 HDACs deacetylate histones 19/642 94/10654 2.5583044249613024e-6 1.2416875033284983e-5 5.870410065645623e-6 57504/5931/5928/57459/51317/8841/54815/9611/23186/3065/3066/5978/53615/9112/1107/9219/9612/23028/1108 19 Gallid_herpesvirus_2 R-HSA-171007 p38MAPK events 7/642 13/10654 3.48258853471361e-6 1.683251125111578e-5 7.958020292042942e-6 1432/3845/5600/3265/6300/5603/6714 7 Gallid_herpesvirus_2 R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 9/642 23/10654 3.7690842655543437e-6 1.8141650406817588e-5 8.576950872914668e-6 7311/5601/5602/5599/7316/6416/5609/7314/6233 9 Gallid_herpesvirus_2 R-HSA-8953750 Transcriptional Regulation by E2F6 11/642 35/10654 3.8490446649313205e-6 1.844996616248071e-5 8.722715399866106e-6 672/80012/5931/5928/4149/8726/23512/2146/1911/6045/6015 11 Gallid_herpesvirus_2 R-HSA-5654732 Negative regulation of FGFR3 signaling 10/642 29/10654 4.140166530966189e-6 1.9682758917708115e-5 9.305551176157829e-6 7311/2261/867/7316/5781/6714/5594/7314/6233/5595 10 Gallid_herpesvirus_2 R-HSA-8863795 Downregulation of ERBB2 signaling 10/642 29/10654 4.140166530966189e-6 1.9682758917708115e-5 9.305551176157829e-6 7311/2064/1956/3320/7316/1950/10273/207/7314/6233 10 Gallid_herpesvirus_2 R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 8/642 18/10654 4.244698083337488e-6 2.0097346027230555e-5 9.50155833047833e-6 3665/7311/7099/7316/5781/3661/7314/6233 8 Gallid_herpesvirus_2 R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 12/642 42/10654 4.2919246462655755e-6 2.02383438604393e-5 9.568218830570666e-6 7311/9070/6657/7316/1499/3065/207/8085/6934/7314/6233/5929 12 Gallid_herpesvirus_2 R-HSA-168638 NOD1/2 Signaling Pathway 11/642 36/10654 5.243962602080425e-6 2.4528212171021342e-5 1.1596368912070889e-5 7311/1432/5600/7316/3551/6300/842/5603/83737/7314/6233 11 Gallid_herpesvirus_2 R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 11/642 36/10654 5.243962602080425e-6 2.4528212171021342e-5 1.1596368912070889e-5 409/60/2335/3845/408/5604/3265/1445/6714/5594/5595 11 Gallid_herpesvirus_2 R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 9/642 24/10654 5.710142535998021e-6 2.6601467235974718e-5 1.2576555744049754e-5 1385/2353/1956/595/1950/2002/207/5594/5595 9 Gallid_herpesvirus_2 R-HSA-373760 L1CAM interactions 21/642 119/10654 7.488231086713833e-6 3.4745392242352185e-5 1.642681429969645e-5 163/6196/1173/1759/1213/1956/1211/161/60/160/5604/3312/1175/6456/1457/10048/6714/5594/26052/5595/1785 21 Gallid_herpesvirus_2 R-HSA-73854 RNA Polymerase I Promoter Clearance 20/642 110/10654 7.725331744844035e-6 3.5702728382546137e-5 1.68794205873925e-5 57504/5931/8850/5928/5437/5441/5434/5440/57459/6908/54815/5435/3065/3066/53615/9112/1107/9219/1108/5595 20 Gallid_herpesvirus_2 R-HSA-109581 Apoptosis 27/642 178/10654 7.794088041368272e-6 3.587754812693331e-5 1.6962071301390435e-5 7311/7161/28988/3837/7099/999/5588/836/7186/5599/7431/7316/1499/10018/842/6774/7157/8795/356/207/54205/6304/5594/7314/6233/5595/3146 27 Gallid_herpesvirus_2 R-HSA-8877330 RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) 6/642 10/10654 7.973354370965855e-6 3.6557672214705106e-5 1.7283618170473103e-5 3558/4773/50943/3559/3458/861 6 Gallid_herpesvirus_2 R-HSA-5688426 Deubiquitination 38/642 297/10654 8.087963036747262e-6 3.6858024177888836e-5 1.7425617601343094e-5 4089/672/409/1080/8850/7311/3091/367/387/4088/60/7040/9146/7186/7416/2033/408/7316/5728/79155/7419/890/7417/8027/7157/4792/154/10254/4087/2625/8678/2099/4609/7314/6233/7415/4193/7528 38 Gallid_herpesvirus_2 R-HSA-162909 Host Interactions of HIV factors 22/642 129/10654 8.102410487380736e-6 3.6858024177888836e-5 1.7425617601343094e-5 163/7311/5905/1173/3932/3837/164/161/160/919/2534/375/7316/3159/1175/920/567/926/940/7314/6233/4869 22 Gallid_herpesvirus_2 R-HSA-446652 Interleukin-1 family signaling 23/642 140/10654 9.641499516395649e-6 4.368804468366778e-5 2.0654692631752194e-5 7311/3552/5777/351/4088/4790/5599/7316/5604/3565/3551/79155/6416/5781/6774/5970/4792/3606/3553/8809/7314/6233/3146 23 Gallid_herpesvirus_2 R-HSA-73864 RNA Polymerase I Transcription 20/642 112/10654 1.0238424024101032e-5 4.621234189866614e-5 2.184812171434216e-5 57504/5931/8850/5928/5437/5441/5434/5440/57459/6908/54815/5435/3065/3066/53615/9112/1107/9219/1108/5595 20 Gallid_herpesvirus_2 R-HSA-5357801 Programmed Cell Death 27/642 181/10654 1.0688160176099686e-5 4.805529381502184e-5 2.271942656771904e-5 7311/7161/28988/3837/7099/999/5588/836/7186/5599/7431/7316/1499/10018/842/6774/7157/8795/356/207/54205/6304/5594/7314/6233/5595/3146 27 Gallid_herpesvirus_2 R-HSA-3232118 SUMOylation of transcription factors 8/642 20/10654 1.0968436188623014e-5 4.91250423891996e-5 2.322517884280671e-5 7020/7341/9063/7157/9112/7329/4193/8554 8 Gallid_herpesvirus_2 R-HSA-2173789 TGF-beta receptor signaling activates SMADs 10/642 32/10654 1.1306307138451845e-5 5.025025394867487e-5 2.3757152728910712e-5 4089/7311/867/4088/7040/7316/10273/4087/7314/6233 10 Gallid_herpesvirus_2 R-HSA-381042 PERK regulates gene expression 10/642 32/10654 1.1306307138451845e-5 5.025025394867487e-5 2.3757152728910712e-5 1054/9451/6347/1051/467/1649/3576/468/8570/4800 10 Gallid_herpesvirus_2 R-HSA-2132295 MHC class II antigen presentation 21/642 123/10654 1.2738948215835366e-5 5.640145011591231e-5 2.6665295381479414e-5 163/3120/3123/1173/1759/1213/164/1211/161/3117/160/3127/3115/375/3122/1175/3119/6456/3113/26052/1785 21 Gallid_herpesvirus_2 R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 10/642 33/10654 1.535481446245142e-5 6.671111578987619e-5 3.1539465813544005e-5 7311/351/4790/7316/3551/5970/4792/7314/6233/3146 10 Gallid_herpesvirus_2 R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 12/642 47/10654 1.5355058548187018e-5 6.671111578987619e-5 3.1539465813544005e-5 409/60/2335/3845/408/5604/3265/1445/5245/6714/5594/5595 12 Gallid_herpesvirus_2 R-HSA-6802949 Signaling by RAS mutants 12/642 47/10654 1.5355058548187018e-5 6.671111578987619e-5 3.1539465813544005e-5 409/60/2335/3845/408/5604/3265/1445/5245/6714/5594/5595 12 Gallid_herpesvirus_2 R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 12/642 47/10654 1.5355058548187018e-5 6.671111578987619e-5 3.1539465813544005e-5 409/60/2335/3845/408/5604/3265/1445/5245/6714/5594/5595 12 Gallid_herpesvirus_2 R-HSA-9649948 Signaling downstream of RAS mutants 12/642 47/10654 1.5355058548187018e-5 6.671111578987619e-5 3.1539465813544005e-5 409/60/2335/3845/408/5604/3265/1445/5245/6714/5594/5595 12 Gallid_herpesvirus_2 R-HSA-5674135 MAP2K and MAPK activation 11/642 40/10654 1.617163104836632e-5 6.973640154685848e-5 3.296975064057466e-5 409/60/2335/3845/408/5604/3265/1445/6714/5594/5595 11 Gallid_herpesvirus_2 R-HSA-5675221 Negative regulation of MAPK pathway 11/642 40/10654 1.617163104836632e-5 6.973640154685848e-5 3.296975064057466e-5 7311/1843/3845/7316/5604/3265/1847/5594/7314/6233/5595 11 Gallid_herpesvirus_2 R-HSA-193704 p75 NTR receptor-mediated signalling 18/642 97/10654 1.634642608705115e-5 7.022908985547902e-5 3.32026822274996e-5 7409/7311/387/8841/836/4790/5599/6453/7316/4803/10018/3551/3065/3066/5970/4792/7314/6233 18 Gallid_herpesvirus_2 R-HSA-389513 CTLA4 inhibitory signaling 8/642 21/10654 1.678764557881056e-5 7.185855672110794e-5 3.3973056308255206e-5 941/3932/4067/2534/5781/207/942/6714 8 Gallid_herpesvirus_2 R-HSA-1368108 BMAL1:CLOCK,NPAS2 activates circadian gene expression 9/642 27/10654 1.7379577937719313e-5 7.384729087089525e-5 3.491328361500583e-5 1387/23054/6604/5465/406/5469/8648/551/10498 9 Gallid_herpesvirus_2 R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress 9/642 27/10654 1.7379577937719313e-5 7.384729087089525e-5 3.491328361500583e-5 1054/6347/1051/467/1649/3576/468/8570/4800 9 Gallid_herpesvirus_2 R-HSA-9614657 FOXO-mediated transcription of cell death genes 7/642 16/10654 1.978748981757294e-5 8.377185470213362e-5 3.960538684193432e-5 604/1387/1649/2033/10018/356/4800 7 Gallid_herpesvirus_2 R-HSA-5654727 Negative regulation of FGFR2 signaling 10/642 34/10654 2.059026705935532e-5 8.685349014128062e-5 4.106231248966171e-5 7311/867/7316/5781/2263/6714/5594/7314/6233/5595 10 Gallid_herpesvirus_2 R-HSA-73894 DNA Repair 40/642 334/10654 2.2904877869190603e-5 9.626687800094601e-5 4.55127435920988e-5 672/9318/7311/5531/22976/7341/25/3838/5437/5441/5434/5440/3980/4436/60/5438/5431/5599/5591/2033/5435/7316/142/5433/2547/890/5439/10987/5430/7157/5432/5436/7329/641/7314/6233/7415/8554/10980/7528 40 Gallid_herpesvirus_2 R-HSA-389357 CD28 dependent PI3K/Akt signaling 8/642 22/10654 2.4995998069991536e-5 1.0467638180935083e-4 4.9488561635818315e-5 2475/941/3932/5290/2534/207/942/940 8 Gallid_herpesvirus_2 R-HSA-389359 CD28 dependent Vav1 pathway 6/642 12/10654 3.159878261937416e-5 1.3137845103395706e-4 6.211267966305956e-5 7409/941/3932/2534/942/940 6 Gallid_herpesvirus_2 R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 6/642 12/10654 3.159878261937416e-5 1.3137845103395706e-4 6.211267966305956e-5 3665/7311/7316/3661/7314/6233 6 Gallid_herpesvirus_2 R-HSA-180292 GAB1 signalosome 7/642 17/10654 3.18963125195288e-5 1.321418661523336e-4 6.24736045965207e-5 1956/5290/55824/1950/1445/5781/6714 7 Gallid_herpesvirus_2 R-HSA-186763 Downstream signal transduction 9/642 29/10654 3.330581995128433e-5 1.3749021759249045e-4 6.500218091260212e-5 5290/6778/5335/3845/3265/5781/6774/6772/6714 9 Gallid_herpesvirus_2 R-HSA-73887 Death Receptor Signalling 22/642 141/10654 3.433078337228489e-5 1.4121882521932793e-4 6.676497998118862e-5 7409/7124/7311/387/8841/836/7186/4790/5599/6453/7316/4803/10018/3551/3065/3066/5970/4792/8795/356/7314/6233 22 Gallid_herpesvirus_2 R-HSA-6804757 Regulation of TP53 Degradation 10/642 36/10654 3.576475348444988e-5 1.4659757612000657e-4 6.930792845601038e-5 2475/7311/1616/7316/890/7157/207/7314/6233/4193 10 Gallid_herpesvirus_2 R-HSA-451927 Interleukin-2 family signaling 11/642 44/10654 4.301351719090982e-5 1.7446041937571813e-4 8.248083347980869e-5 5777/3932/3558/6464/3636/5290/3559/6774/6850/6775/6772 11 Gallid_herpesvirus_2 R-HSA-69231 Cyclin D associated events in G1 11/642 44/10654 4.301351719090982e-5 1.7446041937571813e-4 8.248083347980869e-5 5925/7311/25/1019/4067/7316/595/1026/6714/7314/6233 11 Gallid_herpesvirus_2 R-HSA-69236 G1 Phase 11/642 44/10654 4.301351719090982e-5 1.7446041937571813e-4 8.248083347980869e-5 5925/7311/25/1019/4067/7316/595/1026/6714/7314/6233 11 Gallid_herpesvirus_2 R-HSA-525793 Myogenesis 9/642 30/10654 4.506070569148532e-5 1.8212689408405217e-4 8.610536462594481e-5 4654/1432/4208/25/4209/5600/1499/6300/4205 9 Gallid_herpesvirus_2 R-HSA-6806003 Regulation of TP53 Expression and Degradation 10/642 37/10654 4.639591851348322e-5 1.868724495681963e-4 8.834895301726886e-5 2475/7311/1616/7316/890/7157/207/7314/6233/4193 10 Gallid_herpesvirus_2 R-HSA-5675482 Regulation of necroptotic cell death 7/642 18/10654 4.949279443346882e-5 1.9865619911011706e-4 9.392003605841288e-5 7311/7186/7316/8795/356/7314/6233 7 Gallid_herpesvirus_2 R-HSA-933542 TRAF6 mediated NF-kB activation 8/642 24/10654 5.162045688053796e-5 2.0648182752215183e-4 9.761981137844021e-5 351/7186/4790/3551/5970/4792/3146/4214 8 Gallid_herpesvirus_2 R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 6/642 13/10654 5.569837754908318e-5 2.2126752724978247e-4 1.0461014673061404e-4 7311/2064/7316/207/7314/6233 6 Gallid_herpesvirus_2 R-HSA-209543 p75NTR recruits signalling complexes 6/642 13/10654 5.569837754908318e-5 2.2126752724978247e-4 1.0461014673061404e-4 7311/7316/4803/3551/7314/6233 6 Gallid_herpesvirus_2 R-HSA-5689896 Ovarian tumor domain proteases 10/642 38/10654 5.960798663923563e-5 2.351879744949433e-4 1.111914108093153e-4 7311/387/7316/5728/79155/7157/2099/7314/6233/7415 10 Gallid_herpesvirus_2 R-HSA-5696394 DNA Damage Recognition in GG-NER 10/642 38/10654 5.960798663923563e-5 2.351879744949433e-4 1.111914108093153e-4 9318/7311/60/7316/142/10987/7314/6233/10980/7528 10 Gallid_herpesvirus_2 R-HSA-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function 17/642 97/10654 5.98487996487289e-5 2.3533765285601874e-4 1.112621752613301e-4 27327/8850/9070/58508/5588/192670/4343/11091/2033/26523/192669/3065/861/8085/23112/57690/5929 17 Gallid_herpesvirus_2 R-HSA-5654733 Negative regulation of FGFR4 signaling 9/642 31/10654 6.0135030988028515e-5 2.3566431062876038e-4 1.1141661146786222e-4 7311/867/7316/5781/6714/5594/7314/6233/5595 9 Gallid_herpesvirus_2 R-HSA-5684996 MAPK1/MAPK3 signaling 32/642 255/10654 6.120349484907211e-5 2.3904395294587088e-4 1.1301442784464495e-4 409/7311/2261/27040/2064/3558/6464/1956/60/3667/1843/2335/3845/2534/408/7316/5604/3265/1950/3559/1445/5781/3569/2263/10048/1847/5245/6714/5594/7314/6233/5595 32 Gallid_herpesvirus_2 R-HSA-202733 Cell surface interactions at the vascular wall 21/642 137/10654 6.718871147169388e-5 2.6153995069518423e-4 1.2365001298746914e-4 914/5777/3932/4312/4067/6383/6464/5290/7040/338/5335/2335/3845/2534/960/3265/5781/8795/2207/6714/6402 21 Gallid_herpesvirus_2 R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 8/642 25/10654 7.193674273911896e-5 2.7815540525792665e-4 1.315054139195824e-4 2475/1385/2932/6199/842/1026/207/4193 8 Gallid_herpesvirus_2 R-HSA-9006335 Signaling by Erythropoietin 8/642 25/10654 7.193674273911896e-5 2.7815540525792665e-4 1.315054139195824e-4 7409/4067/6464/5290/5335/3845/3265/2056 8 Gallid_herpesvirus_2 R-HSA-6804760 Regulation of TP53 Activity through Methylation 7/642 19/10654 7.431167591447394e-5 0.00028638386731159393 1.353956396273507e-4 7311/2033/7316/7157/7314/6233/4193 7 Gallid_herpesvirus_2 R-HSA-1169408 ISG15 antiviral mechanism 14/642 72/10654 8.297177317627057e-5 3.186995261075293e-4 1.5067373239747983e-4 7311/3837/3838/25820/5300/5335/7316/3661/4734/1974/6772/7314/6233/5595 14 Gallid_herpesvirus_2 R-HSA-72613 Eukaryotic Translation Initiation 19/642 119/10654 8.441136022239792e-5 3.2209597979599206e-4 1.5227949680010153e-4 8890/7311/6204/6223/8664/6146/8662/6141/8663/6203/3921/6206/8891/6175/6129/6176/1974/8668/6233 19 Gallid_herpesvirus_2 R-HSA-72737 Cap-dependent Translation Initiation 19/642 119/10654 8.441136022239792e-5 3.2209597979599206e-4 1.5227949680010153e-4 8890/7311/6204/6223/8664/6146/8662/6141/8663/6203/3921/6206/8891/6175/6129/6176/1974/8668/6233 19 Gallid_herpesvirus_2 R-HSA-877312 Regulation of IFNG signaling 6/642 14/10654 9.251956228891706e-5 3.507277524677902e-4 1.658159337892184e-4 5777/7341/3458/5781/6772/8554 6 Gallid_herpesvirus_2 R-HSA-9027284 Erythropoietin activates RAS 6/642 14/10654 9.251956228891706e-5 3.507277524677902e-4 1.658159337892184e-4 7409/4067/6464/3845/3265/2056 6 Gallid_herpesvirus_2 R-HSA-111885 Opioid Signalling 16/642 91/10654 9.418085695353477e-5 3.5586252138794896e-4 1.6824353325147135e-4 1385/3838/54331/2775/5530/2782/1020/5567/2770/2781/2771/2773/5532/5594/5568/5566 16 Gallid_herpesvirus_2 R-HSA-2173788 Downregulation of TGF-beta receptor signaling 8/642 26/10654 9.847071127861238e-5 3.708637178025661e-4 1.7533575043115877e-4 7311/4088/7040/7316/10273/4087/7314/6233 8 Gallid_herpesvirus_2 R-HSA-5654726 Negative regulation of FGFR1 signaling 9/642 33/10654 1.0319958860418571e-4 3.874159313296292e-4 1.8316125247072306e-4 7311/867/7316/5781/6714/5594/7314/6233/5595 9 Gallid_herpesvirus_2 R-HSA-5213460 RIPK1-mediated regulated necrosis 7/642 20/10654 1.0841957422839328e-4 4.043945533920778e-4 1.9118835056013844e-4 7311/7186/7316/8795/356/7314/6233 7 Gallid_herpesvirus_2 R-HSA-5218859 Regulated Necrosis 7/642 20/10654 1.0841957422839328e-4 4.043945533920778e-4 1.9118835056013844e-4 7311/7186/7316/8795/356/7314/6233 7 Gallid_herpesvirus_2 R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 15/642 83/10654 1.122196240344473e-4 4.172268073075605e-4 1.9725514211183217e-4 7311/4773/4790/3845/5530/7316/3265/3551/4772/5970/4792/5532/7314/6233/4775 15 Gallid_herpesvirus_2 R-HSA-447115 Interleukin-12 family signaling 12/642 57/10654 1.1934415567391388e-4 4.4229782933463295e-4 2.0910813891410502e-4 2939/6845/302/375/6175/3458/3181/6774/6648/6775/3586/6772 12 Gallid_herpesvirus_2 R-HSA-9012852 Signaling by NOTCH3 11/642 49/10654 1.2404357878758782e-4 4.5825016367389133e-4 2.166500320091628e-4 8850/7311/1387/1956/2033/7316/1950/4851/6772/7314/6233 11 Gallid_herpesvirus_2 R-HSA-8866910 TFAP2 (AP-2) family regulates transcription of growth factors and their receptors 6/642 15/10654 1.4637323657799595e-4 5.39025252160239e-4 2.5483861740062126e-4 7020/2064/1956/7422/2099/7528 6 Gallid_herpesvirus_2 R-HSA-9607240 FLT3 Signaling 32/642 267/10654 1.4736631441866917e-4 5.409649516634691e-4 2.557556622655784e-4 409/7311/2261/27040/2064/3558/6464/1956/60/5290/3667/1843/2335/3845/2534/408/7316/5604/3265/1950/3559/1445/5781/2263/10048/1847/5245/6714/5594/7314/6233/5595 32 Gallid_herpesvirus_2 R-HSA-373752 Netrin-1 signaling 11/642 50/10654 1.505126505582546e-4 5.507718443141178e-4 2.603921332918833e-4 1432/5588/5335/5599/2534/5600/6300/5603/5781/6714/8976 11 Gallid_herpesvirus_2 R-HSA-74749 Signal attenuation 5/642 10/10654 1.5290841418388225e-4 5.577791209223378e-4 2.637050108897804e-4 6464/3667/3630/5594/5595 5 Gallid_herpesvirus_2 R-HSA-909733 Interferon alpha/beta signaling 13/642 69/10654 2.0625823256743367e-4 7.500299366088497e-4 3.545967304657085e-4 3665/1958/5777/3662/3456/3663/5781/3664/3661/3105/3660/6772/3659 13 Gallid_herpesvirus_2 R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 7/642 22/10654 2.1454732411200909e-4 7.734977960916633e-4 3.656917892593073e-4 3725/351/8851/10018/1020/356/6648 7 Gallid_herpesvirus_2 R-HSA-8863678 Neurodegenerative Diseases 7/642 22/10654 2.1454732411200909e-4 7.734977960916633e-4 3.656917892593073e-4 3725/351/8851/10018/1020/356/6648 7 Gallid_herpesvirus_2 R-HSA-5673001 RAF/MAP kinase cascade 30/642 249/10654 2.1471231925992724e-4 7.734977960916633e-4 3.656917892593073e-4 409/7311/2261/27040/2064/3558/6464/1956/60/3667/1843/2335/3845/2534/408/7316/5604/3265/1950/3559/1445/2263/10048/1847/5245/6714/5594/7314/6233/5595 30 Gallid_herpesvirus_2 R-HSA-1433559 Regulation of KIT signaling 6/642 16/10654 2.2232468463425034e-4 7.910939698642037e-4 3.7401085145122515e-4 5777/867/3932/4067/2534/6714 6 Gallid_herpesvirus_2 R-HSA-205043 NRIF signals cell death from the nucleus 6/642 16/10654 2.2232468463425034e-4 7.910939698642037e-4 3.7401085145122515e-4 7311/5599/7316/4803/7314/6233 6 Gallid_herpesvirus_2 R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 6/642 16/10654 2.2232468463425034e-4 7.910939698642037e-4 3.7401085145122515e-4 7311/387/7040/7316/7314/6233 6 Gallid_herpesvirus_2 R-HSA-2559584 Formation of Senescence-Associated Heterochromatin Foci (SAHF) 6/642 16/10654 2.2232468463425034e-4 7.910939698642037e-4 3.7401085145122515e-4 5925/29855/3159/7290/25842/7157 6 Gallid_herpesvirus_2 R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 8/642 29/10654 2.303021306604889e-4 8.169739191625906e-4 3.8624629027559867e-4 4089/4088/2908/3630/3065/3066/6648/4087 8 Gallid_herpesvirus_2 R-HSA-109606 Intrinsic Pathway for Apoptosis 11/642 53/10654 2.604224398868715e-4 9.210061898438139e-4 4.3543033113305543e-4 7161/836/5599/10018/842/6774/7157/207/54205/5594/5595 11 Gallid_herpesvirus_2 R-HSA-1059683 Interleukin-6 signaling 5/642 11/10654 2.664594870534067e-4 9.338157250210024e-4 4.41486381793051e-4 867/5781/6774/3569/6772 5 Gallid_herpesvirus_2 R-HSA-2025928 Calcineurin activates NFAT 5/642 11/10654 2.664594870534067e-4 9.338157250210024e-4 4.41486381793051e-4 4773/5530/4772/5532/4775 5 Gallid_herpesvirus_2 R-HSA-376172 DSCAM interactions 5/642 11/10654 2.664594870534067e-4 9.338157250210024e-4 4.41486381793051e-4 1432/5599/5600/6300/5603 5 Gallid_herpesvirus_2 R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 14/642 80/10654 2.6793952516350163e-4 9.361742445471744e-4 4.426014350354608e-4 7311/3837/3838/25820/5300/5335/7316/3661/4734/1974/6772/7314/6233/5595 14 Gallid_herpesvirus_2 R-HSA-3214841 PKMTs methylate histone lysines 13/642 71/10654 2.7747810501766216e-4 9.636964126361919e-4 4.556132767544973e-4 5931/9070/5928/58508/8726/11091/4790/23512/2146/5970/8085/2122/5929 13 Gallid_herpesvirus_2 R-HSA-6802957 Oncogenic MAPK signaling 13/642 71/10654 2.7747810501766216e-4 9.636964126361919e-4 4.556132767544973e-4 409/60/2335/3845/408/5604/3265/10018/1445/5245/6714/5594/5595 13 Gallid_herpesvirus_2 R-HSA-112409 RAF-independent MAPK1/3 activation 7/642 23/10654 2.9252308270102197e-4 0.001012915749054285 4.7888303562366834e-4 1843/5604/5781/3569/1847/5594/5595 7 Gallid_herpesvirus_2 R-HSA-112043 PLC beta mediated events 11/642 54/10654 3.0955906902186553e-4 0.0010655445699268961 5.03764719538941e-4 1385/3838/2775/5567/2770/2781/2771/2773/5594/5568/5566 11 Gallid_herpesvirus_2 R-HSA-74751 Insulin receptor signalling cascade 11/642 54/10654 3.0955906902186553e-4 0.0010655445699268961 5.03764719538941e-4 2261/6464/5290/3667/3845/3265/5781/3630/2263/5594/5595 11 Gallid_herpesvirus_2 R-HSA-5689880 Ub-specific processing proteases 27/642 220/10654 3.255983450520723e-4 0.0011174381072793014 5.282987784868566e-4 4089/409/1080/7311/3091/367/4088/9146/7186/7416/408/7316/5728/7419/890/7417/7157/4792/154/10254/4087/2625/8678/4609/7314/6233/4193 27 Gallid_herpesvirus_2 R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 17/642 111/10654 3.2814557656354117e-4 0.0011219100462919658 5.304130073667098e-4 7311/6204/6223/8664/6146/8662/6141/8663/6203/3921/6206/6175/6129/6176/1974/8668/6233 17 Gallid_herpesvirus_2 R-HSA-5607764 CLEC7A (Dectin-1) signaling 16/642 101/10654 3.2980286705651754e-4 0.0011219100462919658 5.304130073667098e-4 7311/4773/4790/5530/7316/3551/4772/5970/4792/6850/3553/5532/6714/7314/6233/4775 16 Gallid_herpesvirus_2 R-HSA-72689 Formation of a pool of free 40S subunits 16/642 101/10654 3.2980286705651754e-4 0.0011219100462919658 5.304130073667098e-4 7311/6204/6223/8664/6146/8662/6141/8663/6203/3921/6206/6175/6129/6176/8668/6233 16 Gallid_herpesvirus_2 R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 9/642 38/10654 3.3266747077964447e-4 0.0011283458073227707 5.33455685676192e-4 2939/302/375/6175/3458/3181/6648/6775/3586 9 Gallid_herpesvirus_2 R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 17/642 112/10654 3.6571713291233006e-4 0.0012351076951160158 5.839302260938695e-4 7311/6204/6223/8664/6146/8662/6141/8663/6203/3921/6206/6175/6129/6176/1974/8668/6233 17 Gallid_herpesvirus_2 R-HSA-112040 G-protein mediated events 11/642 55/10654 3.662733164826805e-4 0.0012351076951160158 5.839302260938695e-4 1385/3838/2775/5567/2770/2781/2771/2773/5594/5568/5566 11 Gallid_herpesvirus_2 R-HSA-2122948 Activated NOTCH1 Transmits Signal to the Nucleus 8/642 31/10654 3.802809506894729e-4 0.0012749303549126835 6.027574545458331e-4 409/7311/408/7316/4851/83737/7314/6233 8 Gallid_herpesvirus_2 R-HSA-5339562 Uptake and actions of bacterial toxins 8/642 31/10654 3.802809506894729e-4 0.0012749303549126835 6.027574545458331e-4 127833/6857/3320/5604/6416/5609/3326/6844 8 Gallid_herpesvirus_2 R-HSA-452723 Transcriptional regulation of pluripotent stem cells 7/642 24/10654 3.9171828156828024e-4 0.001305727605227601 6.173176790595099e-4 4089/2034/2516/6657/6774/4087/57167 7 Gallid_herpesvirus_2 R-HSA-982772 Growth hormone receptor signaling 7/642 24/10654 3.9171828156828024e-4 0.001305727605227601 6.173176790595099e-4 5777/4067/3667/6774/6772/5594/5595 7 Gallid_herpesvirus_2 R-HSA-4570464 SUMOylation of RNA binding proteins 10/642 47/10654 3.9923842886761693e-4 0.0013231902213898161 6.25573598315875e-4 1912/80012/7341/84733/57332/8535/1911/7329/6045/6015 10 Gallid_herpesvirus_2 R-HSA-9020591 Interleukin-12 signaling 10/642 47/10654 3.9923842886761693e-4 0.0013231902213898161 6.25573598315875e-4 2939/6845/302/375/6175/3458/3181/6648/6775/3586 10 Gallid_herpesvirus_2 R-HSA-1912408 Pre-NOTCH Transcription and Translation 15/642 93/10654 4.117463816462222e-4 0.0013607572726769736 6.433344274634332e-4 27327/8850/3725/1387/192670/4343/2033/595/26523/192669/4851/7157/861/23112/57690 15 Gallid_herpesvirus_2 R-HSA-5689877 Josephin domain DUBs 5/642 12/10654 4.3421713307771436e-4 0.0014268891625216675 6.746000487057975e-4 7311/7316/7314/6233/7415 5 Gallid_herpesvirus_2 R-HSA-9020558 Interleukin-2 signaling 5/642 12/10654 4.3421713307771436e-4 0.0014268891625216675 6.746000487057975e-4 3932/3558/6464/3559/6850 5 Gallid_herpesvirus_2 R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 14/642 84/10654 4.5122806325878403e-4 0.0014786004332773715 6.990479362409351e-4 9318/7311/7341/3980/60/7316/142/10987/7329/7314/6233/8554/10980/7528 14 Gallid_herpesvirus_2 R-HSA-8963898 Plasma lipoprotein assembly 6/642 18/10654 4.6454566146486754e-4 0.0015179520205612573 7.176524525521009e-4 338/335/5567/336/5568/5566 6 Gallid_herpesvirus_2 R-HSA-917729 Endosomal Sorting Complex Required For Transport (ESCRT) 8/642 32/10654 4.8062729327624256e-4 0.0015660889331473072 7.404104665787178e-4 7311/7251/9146/7316/8027/10254/7314/6233 8 Gallid_herpesvirus_2 R-HSA-211000 Gene Silencing by RNA 19/642 136/10654 4.982803045345832e-4 0.0016190620539499063 7.654549275026328e-4 27327/5437/5441/5434/5440/192670/5438/3320/5431/5435/5433/26523/5439/192669/5430/5432/5436/23112/57690 19 Gallid_herpesvirus_2 R-HSA-5654708 Downstream signaling of activated FGFR3 7/642 25/10654 5.160777688907328e-4 0.0016722072958470669 7.905807632815988e-4 2261/6464/5290/5335/3845/3265/5781 7 Gallid_herpesvirus_2 R-HSA-157858 Gap junction trafficking and regulation 10/642 49/10654 5.681962783570786e-4 0.0018359545484518418 8.679966603842192e-4 1173/1759/1213/1211/60/8218/1212/6714/1601/1785 10 Gallid_herpesvirus_2 R-HSA-5628897 TP53 Regulates Metabolic Genes 14/642 86/10654 5.772854448924095e-4 0.0018601419890977638 8.794319204355127e-4 2475/27327/4513/192670/4343/10128/5728/26523/192669/7157/207/54205/23112/57690 14 Gallid_herpesvirus_2 R-HSA-6802952 Signaling by BRAF and RAF fusions 12/642 67/10654 5.823505331442675e-4 0.0018712648710452915 8.846905606303059e-4 409/60/2335/3845/408/5604/3265/10018/1445/6714/5594/5595 12 Gallid_herpesvirus_2 R-HSA-72649 Translation initiation complex formation 11/642 58/10654 5.912290984185402e-4 0.0018893271464614507 8.93229984851557e-4 6204/6223/8664/8662/8663/6203/3921/6206/1974/8668/6233 11 Gallid_herpesvirus_2 R-HSA-72702 Ribosomal scanning and start codon recognition 11/642 58/10654 5.912290984185402e-4 0.0018893271464614507 8.93229984851557e-4 6204/6223/8664/8662/8663/6203/3921/6206/1974/8668/6233 11 Gallid_herpesvirus_2 R-HSA-74158 RNA Polymerase III Transcription 9/642 41/10654 6.079578860913664e-4 0.0019268610597431284 9.109751471199365e-4 5437/5441/5434/5440/6908/5435/4784/2971/5451 9 Gallid_herpesvirus_2 R-HSA-749476 RNA Polymerase III Abortive And Retractive Initiation 9/642 41/10654 6.079578860913664e-4 0.0019268610597431284 9.109751471199365e-4 5437/5441/5434/5440/6908/5435/4784/2971/5451 9 Gallid_herpesvirus_2 R-HSA-8853659 RET signaling 9/642 41/10654 6.079578860913664e-4 0.0019268610597431284 9.109751471199365e-4 5598/6464/5290/5335/5781/5567/6714/5568/5566 9 Gallid_herpesvirus_2 R-HSA-111461 Cytochrome c-mediated apoptotic response 5/642 13/10654 6.707913552831128e-4 0.0021144510112185077 9.996633183710008e-4 836/842/54205/5594/5595 5 Gallid_herpesvirus_2 R-HSA-5607763 CLEC7A (Dectin-1) induces NFAT activation 5/642 13/10654 6.707913552831128e-4 0.0021144510112185077 9.996633183710008e-4 4773/5530/4772/5532/4775 5 Gallid_herpesvirus_2 R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 11/642 59/10654 6.879662467636656e-4 0.0021627123204494636 0.0010224801442415342 6204/6223/8664/8662/8663/6203/3921/6206/1974/8668/6233 11 Gallid_herpesvirus_2 R-HSA-74752 Signaling by Insulin receptor 13/642 78/10654 7.143103678921906e-4 0.002239459531770111 0.0010587644428786097 23545/2261/6464/535/5290/3667/3845/3265/5781/3630/2263/5594/5595 13 Gallid_herpesvirus_2 R-HSA-2426168 Activation of gene expression by SREBF (SREBP) 9/642 42/10654 7.33112377821275e-4 0.0022922112082821534 0.0010837042100862086 1387/23054/6604/5465/5469/8648/4800/6667/10498 9 Gallid_herpesvirus_2 R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 10/642 51/10654 7.923701184041073e-4 0.0024708315520128076 0.0011681517591639499 6204/6223/8664/8662/8663/6203/3921/6206/8668/6233 10 Gallid_herpesvirus_2 R-HSA-3214858 RMTs methylate histone arginines 13/642 79/10654 8.089713469208331e-4 0.0025158358242041994 0.0011894287335847444 5931/6598/1019/6599/6604/8289/11091/6605/6597/6602/595/6601/10498 13 Gallid_herpesvirus_2 R-HSA-9615710 Microautophagy 8/642 35/10654 9.162247671357546e-4 0.002841766657426405 0.0013435212599992351 1080/7311/7251/7431/7316/3312/7314/6233 8 Gallid_herpesvirus_2 R-HSA-9616222 Transcriptional regulation of granulopoiesis 14/642 90/10654 9.205276449900508e-4 0.0028474988485025572 0.0013462313067784321 1385/6688/1051/1019/2624/688/2033/6774/1050/861/1026/5371/4609/1053 14 Gallid_herpesvirus_2 R-HSA-162594 Early Phase of HIV Life Cycle 5/642 14/10654 9.920534625021068e-4 0.0029968281679751147 0.001416830740031792 7852/3159/2547/920/1234 5 Gallid_herpesvirus_2 R-HSA-174490 Membrane binding and targetting of GAG proteins 5/642 14/10654 9.920534625021068e-4 0.0029968281679751147 0.001416830740031792 7311/7251/7316/7314/6233 5 Gallid_herpesvirus_2 R-HSA-174495 Synthesis And Processing Of GAG, GAGPOL Polyproteins 5/642 14/10654 9.920534625021068e-4 0.0029968281679751147 0.001416830740031792 7311/7251/7316/7314/6233 5 Gallid_herpesvirus_2 R-HSA-180336 SHC1 events in EGFR signaling 5/642 14/10654 9.920534625021068e-4 0.0029968281679751147 0.001416830740031792 6464/1956/3845/3265/1950 5 Gallid_herpesvirus_2 R-HSA-198323 AKT phosphorylates targets in the cytosol 5/642 14/10654 9.920534625021068e-4 0.0029968281679751147 0.001416830740031792 2932/842/1026/207/4193 5 Gallid_herpesvirus_2 R-HSA-3371568 Attenuation phase 5/642 14/10654 9.920534625021068e-4 0.0029968281679751147 0.001416830740031792 1387/3320/2033/3312/3326 5 Gallid_herpesvirus_2 R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 5/642 14/10654 9.920534625021068e-4 0.0029968281679751147 0.001416830740031792 8841/9611/3065/9612/5566 5 Gallid_herpesvirus_2 R-HSA-9005895 Pervasive developmental disorders 5/642 14/10654 9.920534625021068e-4 0.0029968281679751147 0.001416830740031792 8841/9611/3065/9612/5566 5 Gallid_herpesvirus_2 R-HSA-918233 TRAF3-dependent IRF activation pathway 5/642 14/10654 9.920534625021068e-4 0.0029968281679751147 0.001416830740031792 3665/1387/2033/3456/3661 5 Gallid_herpesvirus_2 R-HSA-1855204 Synthesis of IP3 and IP4 in the cytosol 7/642 28/10654 0.001085339932580954 0.003244830726272955 0.001534080588374056 3705/3636/5335/5728/3633/4952/8867 7 Gallid_herpesvirus_2 R-HSA-202040 G-protein activation 7/642 28/10654 0.001085339932580954 0.003244830726272955 0.001534080588374056 54331/2775/2782/2770/2781/2771/2773 7 Gallid_herpesvirus_2 R-HSA-76061 RNA Polymerase III Transcription Initiation From Type 1 Promoter 7/642 28/10654 0.001085339932580954 0.003244830726272955 0.001534080588374056 5437/5441/5434/5440/6908/5435/2971 7 Gallid_herpesvirus_2 R-HSA-76071 RNA Polymerase III Transcription Initiation From Type 3 Promoter 7/642 28/10654 0.001085339932580954 0.003244830726272955 0.001534080588374056 5437/5441/5434/5440/6908/5435/5451 7 Gallid_herpesvirus_2 R-HSA-76046 RNA Polymerase III Transcription Initiation 8/642 36/10654 0.0011168338749502442 0.0033304043571781065 0.001574537813148633 5437/5441/5434/5440/6908/5435/2971/5451 8 Gallid_herpesvirus_2 R-HSA-2871837 FCERI mediated NF-kB activation 13/642 82/10654 0.0011583465749694416 0.0034453385306783394 0.0016288760204023727 7311/4067/2206/5588/2205/4790/7316/3551/5970/4792/2207/7314/6233 13 Gallid_herpesvirus_2 R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 6/642 21/10654 0.0011625613496333285 0.0034490311140016904 0.0016306217880171334 4790/3551/1660/5970/4792/3661 6 Gallid_herpesvirus_2 R-HSA-9020702 Interleukin-1 signaling 15/642 103/10654 0.0012319326291148941 0.003645514922891013 0.0017235147684448438 7311/3552/351/4790/7316/5604/3551/79155/6416/5970/4792/3553/7314/6233/3146 15 Gallid_herpesvirus_2 R-HSA-156842 Eukaryotic Translation Elongation 14/642 93/10654 0.0012788283052880072 0.0037746586110282148 0.0017845709041249547 7311/6204/6223/6146/6141/6203/3921/6206/6175/6129/1936/1933/6176/6233 14 Gallid_herpesvirus_2 R-HSA-69202 Cyclin E associated events during G1/S transition 13/642 83/10654 0.0012996370300169089 0.003826342524922879 0.001809005857971706 5925/7311/5928/1019/4149/7316/595/890/1026/207/4609/7314/6233 13 Gallid_herpesvirus_2 R-HSA-416476 G alpha (q) signalling events 25/642 217/10654 0.0013466422425413506 0.00395469620594422 0.00186968849663969 1385/6196/5598/9170/301/351/1956/5588/5290/54331/3845/1128/3265/23566/2782/5996/6869/4314/1902/551/185/695/5594/1906/5595 25 Gallid_herpesvirus_2 R-HSA-5689901 Metalloprotease DUBs 8/642 37/10654 0.0013509961886761705 0.003957463582990803 0.0018709968482197897 672/8850/7311/2033/7316/8027/7314/6233 8 Gallid_herpesvirus_2 R-HSA-5205647 Mitophagy 7/642 29/10654 0.0013573974150101896 0.0039661989959995465 0.001875126748562399 7311/7416/7316/1457/6714/7314/6233 7 Gallid_herpesvirus_2 R-HSA-418594 G alpha (i) signalling events 40/642 406/10654 0.001408234183647144 0.004062565711728786 0.0019206866931131556 1385/3949/3838/9170/301/351/6383/7852/5588/3576/54331/1129/2775/338/4036/5530/2920/335/2921/23566/2782/6352/6351/1020/5996/5567/2770/1902/2781/1234/2771/2773/5532/6714/5594/336/4023/5568/2919/5566 40 Gallid_herpesvirus_2 R-HSA-2691230 Signaling by NOTCH1 HD Domain Mutants in Cancer 5/642 15/10654 0.0014148935754641635 0.004062565711728786 0.0019206866931131556 7311/7316/4851/7314/6233 5 Gallid_herpesvirus_2 R-HSA-2691232 Constitutive Signaling by NOTCH1 HD Domain Mutants 5/642 15/10654 0.0014148935754641635 0.004062565711728786 0.0019206866931131556 7311/7316/4851/7314/6233 5 Gallid_herpesvirus_2 R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 5/642 15/10654 0.0014148935754641635 0.004062565711728786 0.0019206866931131556 7311/7316/3661/7314/6233 5 Gallid_herpesvirus_2 R-HSA-937039 IRAK1 recruits IKK complex 5/642 15/10654 0.0014148935754641635 0.004062565711728786 0.0019206866931131556 7311/7316/3551/7314/6233 5 Gallid_herpesvirus_2 R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 5/642 15/10654 0.0014148935754641635 0.004062565711728786 0.0019206866931131556 3665/7311/7316/7314/6233 5 Gallid_herpesvirus_2 R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 5/642 15/10654 0.0014148935754641635 0.004062565711728786 0.0019206866931131556 7311/7316/3551/7314/6233 5 Gallid_herpesvirus_2 R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF) 10/642 55/10654 0.001459558092429153 0.004180462684488438 0.0019764256430294704 1387/3837/23054/6604/5465/5469/8648/4800/6667/10498 10 Gallid_herpesvirus_2 R-HSA-72163 mRNA Splicing - Major Pathway 22/642 183/10654 0.0014824489404762081 0.004235568401360594 0.0020024783458338206 2962/3178/2963/5437/5441/5434/5440/4670/5438/5431/5435/3312/5433/3181/5439/1655/1660/5430/5432/5436/3184/3187 22 Gallid_herpesvirus_2 R-HSA-1250196 SHC1 events in ERBB2 signaling 6/642 22/10654 0.0015180666092038185 0.004326676330900318 0.002045552058438354 2064/6464/1956/3845/3265/1950 6 Gallid_herpesvirus_2 R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 13/642 85/10654 0.0016254276032001017 0.004621313773804211 0.002184849796871138 5925/7311/5928/1019/4149/7316/595/890/1026/207/4609/7314/6233 13 Gallid_herpesvirus_2 R-HSA-1234174 Cellular response to hypoxia 12/642 75/10654 0.0016334692983122085 0.004632822459760788 0.0021902908362389927 7311/3091/1387/2034/2033/7316/112399/405/7422/7314/6233/2056 12 Gallid_herpesvirus_2 R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 7/642 30/10654 0.0016799253873255853 0.004741395253765643 0.002241621531045281 7124/7311/7186/7316/3551/7314/6233 7 Gallid_herpesvirus_2 R-HSA-5654696 Downstream signaling of activated FGFR2 7/642 30/10654 0.0016799253873255853 0.004741395253765643 0.002241621531045281 6464/5290/5335/3845/3265/5781/2263 7 Gallid_herpesvirus_2 R-HSA-190828 Gap junction trafficking 9/642 47/10654 0.0017115311304140735 0.004818874056505644 0.0022782517091102 1173/1759/1213/1211/60/8218/1212/1601/1785 9 Hantaan_virus R-HSA-165159 mTOR signalling 32/150 40/10654 1.1867853009512606e-53 8.948361169172505e-51 5.434227430671562e-51 10670/2475/51422/7249/55004/6009/58528/5564/1977/6194/6198/8649/153129/5563/5565/7529/208/6794/5571/389541/10542/84335/64121/10325/5562/28956/53632/57521/7248/1978/64223/207 32 Hantaan_virus R-HSA-5628897 TP53 Regulates Metabolic Genes 36/150 86/10654 3.0824159247290086e-45 1.1620708036228362e-42 7.0571101434585194e-43 10670/2475/51422/7249/55004/5728/10971/6009/58528/7531/5564/7533/2810/7534/8649/54541/153129/5563/10000/5565/7529/208/5571/389541/10542/64121/7157/10325/5562/28956/53632/57521/7248/7532/64223/207 36 Hantaan_virus R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK 24/150 29/10654 6.060362604279116e-41 1.5231711345421512e-38 9.250027132847071e-39 10670/2475/51422/7249/55004/6009/58528/5564/8649/153129/5563/5565/6794/5571/389541/10542/64121/10325/5562/28956/53632/57521/7248/64223 24 Hantaan_virus R-HSA-3700989 Transcriptional Regulation by TP53 50/150 365/10654 1.8867379354455532e-36 3.5565010083148677e-34 2.1598184261021463e-34 10670/2475/51422/7249/9150/55004/5728/55615/10971/6009/58528/7531/5564/7533/2810/5300/7534/8649/54541/5170/153129/5563/10000/5565/7529/208/1432/6794/5571/389541/10498/6446/10542/64121/7157/253260/10325/5562/28956/53632/5600/57521/79109/7248/1027/10769/7532/904/64223/207 50 Hantaan_virus R-HSA-166208 mTORC1-mediated signalling 20/150 23/10654 4.331672269442441e-35 6.532161782319201e-33 3.966899867805182e-33 10670/2475/55004/6009/58528/1977/6194/6198/8649/153129/7529/389541/10542/84335/64121/10325/28956/57521/1978/64223 20 Hantaan_virus R-HSA-1257604 PIP3 activates AKT signaling 39/150 264/10654 2.0267068885255549e-29 2.546894989913781e-27 1.546697362295818e-27 10670/2475/7249/55004/5728/55615/6199/6009/58528/5290/2308/8649/5170/153129/3667/2099/10000/5594/208/5781/3630/2932/389541/10542/84335/64121/7157/253260/10325/2885/28956/5595/648/57521/79109/1027/2309/64223/207 39 Hantaan_virus R-HSA-9006925 Intracellular signaling by second messengers 40/150 305/10654 4.005387028891631e-28 4.3143740282632707e-26 2.6200651993501646e-26 10670/2475/7249/55004/5728/55615/6199/6009/58528/5290/2308/801/8649/5170/153129/3667/2099/10000/5594/208/5781/3630/2932/389541/10542/84335/64121/7157/253260/10325/2885/28956/5595/648/57521/79109/1027/2309/64223/207 40 Hantaan_virus R-HSA-1632852 Macroautophagy 25/150 95/10654 1.603166325156827e-25 1.5109842614603096e-23 9.176017782147629e-24 10670/2475/51422/7249/55004/6009/58528/5564/8649/153129/5563/5565/5571/389541/10542/64121/10325/5562/28956/5289/9821/53632/57521/7248/64223 25 Hantaan_virus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 16/150 25/10654 1.930760052005807e-24 1.6175478657915316e-22 9.823165176871651e-23 2475/7249/55615/6199/2308/5170/10000/208/2932/84335/253260/79109/1027/2309/64223/207 16 Hantaan_virus R-HSA-9612973 Autophagy 25/150 119/10654 7.242244586187819e-23 5.460652417985616e-21 3.316185678938633e-21 10670/2475/51422/7249/55004/6009/58528/5564/8649/153129/5563/5565/5571/389541/10542/64121/10325/5562/28956/5289/9821/53632/57521/7248/64223 25 Hantaan_virus R-HSA-2219528 PI3K/AKT Signaling in Cancer 22/150 101/10654 1.407200636934503e-20 9.645720729532865e-19 5.857725139392429e-19 2475/7249/5728/55615/6199/5290/2308/5170/3667/2099/10000/208/5781/2932/84335/253260/2885/79109/1027/2309/64223/207 22 Hantaan_virus R-HSA-8943724 Regulation of PTEN gene transcription 18/150 61/10654 1.3069403482682576e-19 8.211941854952219e-18 4.987009223655194e-18 10670/2475/55004/6009/58528/8649/153129/5594/389541/10542/64121/7157/10325/28956/5595/648/57521/64223 18 Hantaan_virus R-HSA-9614085 FOXO-mediated transcription 18/150 65/10654 4.731116398399476e-19 2.7440475110716957e-17 1.6664256140111513e-17 4087/10971/6720/23411/4088/857/2308/2810/7534/10000/7529/208/6794/3630/1027/2309/7532/207 18 Hantaan_virus R-HSA-5663202 Diseases of signal transduction 34/150 377/10654 1.4489034647821352e-18 7.80338008889807e-17 4.7388947908287876e-17 2475/7249/5728/4087/55615/6199/4088/22938/5290/2308/8312/55869/801/5170/3667/2099/10000/7529/4763/5594/208/5781/2932/5906/867/84335/253260/2885/5595/79109/1027/2309/64223/207 34 Hantaan_virus R-HSA-9614399 Regulation of localization of FOXO transcription factors 10/150 11/10654 2.458441238440832e-18 1.2357764625229249e-16 7.504715359450961e-17 10971/2308/2810/7534/10000/7529/208/2309/7532/207 10 Hantaan_virus R-HSA-6807070 PTEN Regulation 22/150 140/10654 2.4357604945338296e-17 1.1478521330490672e-15 6.970761941593525e-16 10670/2475/55004/5728/6009/58528/8649/153129/10000/5594/208/389541/10542/64121/7157/10325/28956/5595/648/57521/64223/207 22 Hantaan_virus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 17/150 72/10654 9.341967334547369e-17 4.143437276616892e-15 2.5162574554353594e-15 51422/10971/7531/5898/5564/7533/2810/801/7534/5563/5565/7529/208/5571/53632/7532/207 17 Hantaan_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 35/150 473/10654 2.2239932366232935e-16 9.316060557855352e-15 5.657526654568027e-15 2475/6195/55615/857/5898/5290/4914/5747/6196/801/5170/3667/2099/10000/7529/5594/208/1432/5781/3630/5906/867/6197/253260/2885/3479/5595/10653/5289/5600/79109/3480/64223/9261/207 35 Hantaan_virus R-HSA-5633007 Regulation of TP53 Activity 22/150 160/10654 4.573103323336276e-16 1.8147999504187117e-14 1.1021052330478005e-14 2475/51422/55615/5564/5300/5170/5563/10000/5565/208/1432/6794/5571/6446/7157/253260/5562/53632/5600/79109/64223/207 22 Hantaan_virus R-HSA-9639288 Amino acids regulate mTORC1 15/150 55/10654 6.111289435255721e-16 2.2965626808950953e-14 1.3946736928512723e-14 10670/2475/55004/6009/58528/201163/8649/153129/389541/10542/64121/10325/28956/57521/64223 15 Hantaan_virus R-HSA-111447 Activation of BAD and translocation to mitochondria 10/150 15/10654 6.396262108593767e-16 2.2965626808950953e-14 1.3946736928512723e-14 10971/7531/7533/2810/7534/10000/7529/208/7532/207 10 Hantaan_virus R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 8/150 10/10654 5.625603706776168e-14 1.9280478158678323e-12 1.170879240405566e-12 51422/5564/5563/5565/1432/5571/53632/5600 8 Hantaan_virus R-HSA-5218920 VEGFR2 mediated vascular permeability 11/150 29/10654 8.287114449302062e-14 2.7167323020755456e-12 1.6498374304102502e-12 2475/55615/857/801/5170/10000/208/253260/79109/64223/207 11 Hantaan_virus R-HSA-389357 CD28 dependent PI3K/Akt signaling 10/150 22/10654 1.266112579278916e-13 3.899164735458917e-12 2.3679138069588564e-12 2475/55615/5290/5170/10000/208/253260/79109/64223/207 10 Hantaan_virus R-HSA-114452 Activation of BH3-only proteins 11/150 30/10654 1.2928265037993757e-13 3.899164735458917e-12 2.3679138069588564e-12 10971/7531/7533/2810/7534/10000/7529/208/7157/7532/207 11 Hantaan_virus R-HSA-9009391 Extra-nuclear estrogen signaling 15/150 77/10654 1.391699277017552e-13 4.035927903350901e-12 2.450968362358847e-12 595/857/5290/5747/801/5170/2099/10000/5594/208/5595/3480/1027/2309/207 15 Hantaan_virus R-HSA-187037 Signaling by NTRK1 (TRKA) 15/150 80/10654 2.52518098632544e-13 7.0518017173680816e-12 4.282470678563611e-12 6195/5898/5290/4914/6196/3667/7529/5594/1432/5906/6197/2885/5595/5600/9261 15 Hantaan_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 13/150 53/10654 2.6199178629507734e-13 7.055064530946011e-12 4.2844521442991964e-12 10971/7531/7533/2810/7534/10000/7529/5594/208/7157/5595/7532/207 13 Hantaan_virus R-HSA-438064 Post NMDA receptor activation events 15/150 81/10654 3.062125459960843e-13 7.961526195898192e-12 4.834934936780278e-12 51422/6195/5564/6196/801/5170/5563/5565/5594/5571/6197/5562/5595/53632/27330 15 Hantaan_virus R-HSA-4420097 VEGFA-VEGFR2 Pathway 16/150 99/10654 4.4122876813026277e-13 1.0745121843026958e-11 6.525377637465763e-12 2475/55615/857/5290/5747/801/5170/10000/208/1432/253260/5600/79109/64223/9261/207 16 Hantaan_virus R-HSA-389356 CD28 co-stimulation 11/150 33/10654 4.4177556649049823e-13 1.0745121843026958e-11 6.525377637465763e-12 2475/55615/5290/5170/10000/208/253260/2885/79109/64223/207 11 Hantaan_virus R-HSA-166520 Signaling by NTRKs 16/150 101/10654 6.093813200511092e-13 1.435854735370426e-11 8.719765599415542e-12 6195/5898/5290/4914/6196/3667/7529/5594/1432/5781/5906/6197/2885/5595/5600/9261 16 Hantaan_virus R-HSA-6804757 Regulation of TP53 Degradation 11/150 36/10654 1.3227566239658154e-12 3.0222984680915904e-11 1.835403927990844e-11 2475/55615/5170/10000/208/6446/7157/253260/79109/64223/207 11 Hantaan_virus R-HSA-194138 Signaling by VEGF 16/150 107/10654 1.5376792536021978e-12 3.4100298741648736e-11 2.070868344634539e-11 2475/55615/857/5290/5747/801/5170/10000/208/1432/253260/5600/79109/64223/9261/207 16 Hantaan_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 11/150 37/10654 1.859848777220403e-12 4.0066456514976683e-11 2.4331856183184217e-11 2475/55615/5170/10000/208/6446/7157/253260/79109/64223/207 11 Hantaan_virus R-HSA-442755 Activation of NMDA receptors and postsynaptic events 15/150 93/10654 2.5431947607161484e-12 5.3265801377221546e-11 3.234765265823171e-11 51422/6195/5564/6196/801/5170/5563/5565/5594/5571/6197/5562/5595/53632/27330 15 Hantaan_virus R-HSA-2262752 Cellular responses to stress 30/150 479/10654 3.355418249366169e-12 6.837798270329977e-11 4.152509071050593e-11 10670/2475/6195/55004/23411/6009/58528/7531/201163/6196/8649/153129/5594/1432/2932/389541/10542/6197/84335/64121/7157/10325/28956/5595/648/5600/57521/1027/64223/9261 30 Hantaan_virus R-HSA-8953897 Cellular responses to external stimuli 30/150 493/10654 6.974217340843884e-12 1.3838315460516548e-10 8.403835299908834e-11 10670/2475/6195/55004/23411/6009/58528/7531/201163/6196/8649/153129/5594/1432/2932/389541/10542/6197/84335/64121/7157/10325/28956/5595/648/5600/57521/1027/64223/9261 30 Hantaan_virus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 9/150 24/10654 1.8653321443173877e-11 3.6063088123469493e-10 2.190066080372641e-10 595/5747/10000/5594/208/5595/1027/2309/207 9 Hantaan_virus R-HSA-187687 Signalling to ERKs 10/150 34/10654 2.2224340718536355e-11 4.1892882254441034e-10 2.544102161200872e-10 5898/4914/7529/5594/1432/5906/2885/5595/5600/9261 10 Hantaan_virus R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 7/150 13/10654 1.523800419937732e-10 2.80230613812939e-9 1.7018053470421396e-9 10971/7531/7533/2810/7534/7529/7532 7 Hantaan_virus R-HSA-388841 Costimulation by the CD28 family 12/150 70/10654 2.0555120507027266e-10 3.690133538642514e-9 2.240971784600717e-9 2475/55615/5290/5170/10000/208/5781/253260/2885/79109/64223/207 12 Hantaan_virus R-HSA-8939211 ESR-mediated signaling 19/150 223/10654 2.846015162794508e-10 4.990454494760603e-9 3.0306403814335642e-9 595/857/5290/5747/8312/5469/801/5170/2099/10000/5594/208/10498/5595/3480/1027/2309/904/207 19 Hantaan_virus R-HSA-198323 AKT phosphorylates targets in the cytosol 7/150 14/10654 3.011807915078613e-10 5.161143563566532e-9 3.1342977106679344e-9 7249/10000/208/2932/84335/1027/207 7 Hantaan_virus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 8/150 25/10654 1.1307384523539772e-9 1.8946150957219974e-8 1.1505759690619416e-8 6195/6196/5594/1432/6197/5595/5600/9261 8 Hantaan_virus R-HSA-9007101 Rab regulation of trafficking 14/150 124/10654 1.880539348930125e-9 3.0824492806376395e-8 1.871932761520834e-8 7249/5868/51256/51112/7531/5861/27342/10000/208/51693/80006/7248/6399/207 14 Hantaan_virus R-HSA-74751 Insulin receptor signalling cascade 10/150 54/10654 3.189099130138382e-9 5.116129242817745e-8 3.106961078634258e-8 5290/5170/3667/5594/208/5781/3630/2885/5595/5289 10 Hantaan_virus R-HSA-9619483 Activation of AMPK downstream of NMDARs 8/150 29/10654 4.278453091378207e-9 6.720736731039934e-8 4.081419067433158e-8 51422/5564/801/5563/5565/5571/5562/53632 8 Hantaan_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 12/150 92/10654 5.3775401077195796e-9 8.274827022899109e-8 5.0251985969022914e-8 51422/5564/5300/5563/5565/1432/6794/5571/7157/5562/53632/5600 12 Hantaan_virus R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 8/150 30/10654 5.765181791817689e-9 8.693894142061075e-8 5.2796927988225147e-8 6195/6196/801/5170/5594/6197/5595/27330 8 Hantaan_virus R-HSA-9006931 Signaling by Nuclear Receptors 20/150 299/10654 6.574194450083697e-9 9.719495324241389e-8 5.9025275248429475e-8 595/6720/857/5290/5747/8312/5469/801/5170/2099/10000/5594/208/10498/5595/3480/1027/2309/904/207 20 Hantaan_virus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 8/150 31/10654 7.678473711426302e-9 1.1133786881568138e-7 6.761409037389557e-8 6195/6196/5594/1432/6197/5595/5600/9261 8 Hantaan_virus R-HSA-198753 ERK/MAPK targets 7/150 22/10654 1.3617275757211268e-8 1.937250173761754e-7 1.1764677168593648e-7 6195/6196/5594/1432/6197/5595/5600 7 Hantaan_virus R-HSA-449147 Signaling by Interleukins 24/150 461/10654 2.5054382081494244e-8 3.4983340906382704e-7 2.1244943870272895e-7 595/6195/4088/5898/5290/3551/2308/29110/6196/7534/3667/5594/1432/5781/867/6197/7157/2885/5595/5600/375/2309/9261/207 24 Hantaan_virus R-HSA-109581 Apoptosis 15/150 178/10654 2.787888201954447e-8 3.821941280497551e-7 2.3210169719620751e-7 10971/7531/5747/7533/2810/7534/10000/7529/5594/208/7157/5595/1612/7532/207 15 Hantaan_virus R-HSA-5357801 Programmed Cell Death 15/150 181/10654 3.491093905679326e-8 4.7005085801468066e-7 2.8545598664859146e-7 10971/7531/5747/7533/2810/7534/10000/7529/5594/208/7157/5595/1612/7532/207 15 Hantaan_virus R-HSA-2428928 IRS-related events triggered by IGF1R 9/150 52/10654 3.7530733255002456e-8 4.964591732328395e-7 3.0149342504018596e-7 5290/5170/3667/208/5781/2885/3479/5289/3480 9 Hantaan_virus R-HSA-199418 Negative regulation of the PI3K/AKT network 12/150 110/10654 4.196448981482542e-8 5.455383675927304e-7 3.312986038012533e-7 5728/5290/3667/2099/10000/5594/208/5781/3630/2885/5595/207 12 Hantaan_virus R-HSA-2428924 IGF1R signaling cascade 9/150 53/10654 4.4669530630477425e-8 5.708614592437284e-7 3.466769995407257e-7 5290/5170/3667/208/5781/2885/3479/5289/3480 9 Hantaan_virus R-HSA-8876198 RAB GEFs exchange GTP for GDP on RABs 11/150 90/10654 4.780471769653457e-8 6.007459523864511e-7 3.6482547715776383e-007 5868/51112/7531/5861/27342/10000/208/51693/80006/6399/207 11 Hantaan_virus R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 9/150 54/10654 5.2965616930545144e-8 6.546897568136236e-7 3.975848725588807e-7 5290/5170/3667/208/5781/2885/3479/5289/3480 9 Hantaan_virus R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 6/150 17/10654 7.674309043851486e-8 9.33295003074842e-7 5.667783419482845e-7 4087/4088/857/2308/1027/2309 6 Hantaan_virus R-HSA-1592230 Mitochondrial biogenesis 11/150 95/10654 8.44782932483965e-8 1.0110576684014438e-6 6.140026326324558e-7 51422/5469/5564/801/5563/5565/1432/5571/10498/53632/5600 11 Hantaan_virus R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 6/150 18/10654 1.1378268813686299e-7 1.340502294612417e-6 8.140702194002533e-7 6195/6196/5594/6197/2885/5595 6 Hantaan_virus R-HSA-74749 Signal attenuation 5/150 10/10654 1.2322142077369904e-7 1.4293684809749087e-6 8.680375390535884e-7 3667/5594/3630/2885/5595 5 Hantaan_virus R-HSA-74752 Signaling by Insulin receptor 10/150 78/10654 1.2567961797333386e-7 1.4357944235135413e-6 8.719399333078185e-7 5290/5170/3667/5594/208/5781/3630/2885/5595/5289 10 Hantaan_virus R-HSA-166166 MyD88-independent TLR4 cascade 11/150 99/10654 1.29962140159072e-7 1.4410507894108865e-6 8.751320583466923e-7 6195/3551/29110/6196/5594/1432/5781/6197/5595/5600/9261 11 Hantaan_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 11/150 99/10654 1.29962140159072e-7 1.4410507894108865e-6 8.751320583466923e-7 6195/3551/29110/6196/5594/1432/5781/6197/5595/5600/9261 11 Hantaan_virus R-HSA-195258 RHO GTPase Effectors 19/150 327/10654 1.5303654153044782e-7 1.672312352376198e-6 1.0155743030624684e-6 5347/10971/7531/5747/7533/2810/5300/801/7534/5170/7529/5594/1432/2885/5595/5289/5600/1027/7532 19 Hantaan_virus R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission 15/150 206/10654 1.9375782123942966e-7 2.0870485316361426e-6 1.2674383795361186e-6 51422/6195/5564/6196/801/5170/5563/5565/5594/5571/6197/5562/5595/53632/27330 15 Hantaan_virus R-HSA-167044 Signalling to RAS 6/150 20/10654 2.3210381608897265e-7 2.4648771455082446e-6 1.4968889547620918e-6 5898/4914/1432/2885/5600/9261 6 Hantaan_virus R-HSA-450294 MAP kinase activation 9/150 64/10654 2.4336176388137264e-7 2.5485384717577075e-6 1.5476954281929399e-6 6195/3551/6196/5594/1432/6197/5595/5600/9261 9 Hantaan_virus R-HSA-170968 Frs2-mediated activation 5/150 12/10654 3.7854053103488285e-7 3.909856991784954e-6 2.374407080031348e-6 4914/7529/5594/5906/5595 5 Hantaan_virus R-HSA-3371556 Cellular response to heat stress 10/150 89/10654 4.450370272720289e-7 4.534566467069051e-6 2.7537853038880877e-6 2475/23411/7531/5594/2932/84335/5595/57521/64223/9261 10 Hantaan_virus R-HSA-448424 Interleukin-17 signaling 9/150 72/10654 6.834663657795628e-7 6.8711151973038715e-6 4.172742022654173e-6 6195/3551/6196/5594/1432/6197/5595/5600/9261 9 Hantaan_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 10/150 94/10654 7.451799377573287e-7 7.3929693824871815e-6 4.4896575197290575e-6 6195/3551/29110/6196/5594/1432/6197/5595/5600/9261 10 Hantaan_virus R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 6/150 24/10654 7.693587183382231e-7 7.533720436714548e-6 4.57513386845013e-6 5300/5594/1432/5595/5289/5600 6 Hantaan_virus R-HSA-169893 Prolonged ERK activation events 5/150 14/10654 9.353149043358195e-7 9.041377408579588e-6 5.490715025453191e-6 4914/7529/5594/5906/5595 5 Hantaan_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 10/150 97/10654 9.9988585655013e-7 9.543214377706303e-6 5.795474318445123e-6 6195/3551/6196/5594/1432/6197/5595/5289/5600/9261 10 Hantaan_virus R-HSA-9607240 FLT3 Signaling 16/150 267/10654 1.0463797387166464e-6 9.862129037404393e-6 5.989147188707121e-6 5290/5747/801/8649/5170/3667/7529/4763/5594/208/5781/5906/2885/28956/5595/5289 16 Hantaan_virus R-HSA-168898 Toll-like Receptor Cascades 12/150 155/10654 1.7993070074625407e-6 1.6749104736132786e-5 1.0171521094817481e-5 6195/3551/29110/6196/5594/1432/5781/6197/5595/5289/5600/9261 12 Hantaan_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 11/150 129/10654 1.9115802536105014e-6 1.7577213551491684e-5 1.0674421185116406e-5 6195/3551/29110/6196/5594/1432/5781/6197/5595/5600/9261 11 Hantaan_virus R-HSA-1295596 Spry regulation of FGF signaling 5/150 16/10654 1.9947481243565558e-6 1.8120964888733046e-5 1.1004634547813593e-5 5594/5781/867/2885/5595 5 Hantaan_virus R-HSA-109704 PI3K Cascade 7/150 44/10654 2.36079446082742e-6 2.119094075552232e-5 1.2868992361653227e-5 5290/5170/3667/208/5781/2885/5289 7 Hantaan_virus R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 6/150 29/10654 2.561983047995698e-6 2.2726296684573605e-5 1.3801394747716762e-5 4087/6720/4088/2308/3630/2309 6 Hantaan_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 9/150 85/10654 2.830369212232659e-6 2.4251118022993463e-5 1.472739960910534e-5 6195/3551/6196/5594/1432/6197/5595/5600/9261 9 Hantaan_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 9/150 85/10654 2.830369212232659e-6 2.4251118022993463e-5 1.472739960910534e-5 6195/3551/6196/5594/1432/6197/5595/5600/9261 9 Hantaan_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 9/150 85/10654 2.830369212232659e-6 2.4251118022993463e-5 1.472739960910534e-5 6195/3551/6196/5594/1432/6197/5595/5600/9261 9 Hantaan_virus R-HSA-5683057 MAPK family signaling cascades 16/150 294/10654 3.684858035291642e-6 3.1217786051796606e-5 1.895816966708296e-5 896/5747/2308/801/8649/10642/3667/7529/4763/5594/5781/5906/2885/28956/5595/2309 16 Hantaan_virus R-HSA-1852241 Organelle biogenesis and maintenance 16/150 296/10654 4.020725298732005e-6 3.3684743058265916e-5 2.0456321695303183e-5 51422/5347/6102/7531/5469/5310/5564/801/5563/5565/1432/5571/10498/53632/5600/7532 16 Hantaan_virus R-HSA-112399 IRS-mediated signalling 7/150 48/10654 4.327429023476553e-6 3.58558404802343e-5 2.1774801911073456e-5 5290/5170/3667/208/5781/2885/5289 7 Hantaan_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 9/150 92/10654 5.492937899717191e-6 4.5018208438986545e-5 2.7338992979141625e-5 6195/3551/6196/5594/1432/6197/5595/5600/9261 9 Hantaan_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 9/150 93/10654 6.009258228095559e-6 4.8201922382809056e-5 2.927242249968161e-5 6195/3551/6196/5594/1432/6197/5595/5600/9261 9 Hantaan_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 9/150 93/10654 6.009258228095559e-6 4.8201922382809056e-5 2.927242249968161e-5 6195/3551/6196/5594/1432/6197/5595/5600/9261 9 Hantaan_virus R-HSA-112315 Transmission across Chemical Synapses 15/150 272/10654 6.431543385476972e-6 5.1046144343680385e-5 3.09996827998059e-5 51422/6195/5564/6196/801/5170/5563/5565/5594/5571/6197/5562/5595/53632/27330 15 Hantaan_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 9/150 95/10654 7.1677183761587905e-6 5.571607892395596e-5 3.383567545989228e-5 6195/3551/6196/5594/1432/6197/5595/5600/9261 9 Hantaan_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 9/150 95/10654 7.1677183761587905e-6 5.571607892395596e-5 3.383567545989228e-5 6195/3551/6196/5594/1432/6197/5595/5600/9261 9 Hantaan_virus R-HSA-450341 Activation of the AP-1 family of transcription factors 4/150 10/10654 7.422699980058665e-6 5.7109344744532995e-5 3.4681788306396555e-5 5594/1432/5595/5600 4 Hantaan_virus R-HSA-210745 Regulation of gene expression in beta cells 5/150 21/10654 8.779101916187963e-6 6.686305903844166e-5 4.0605096582049584e-5 2308/10000/208/3630/207 5 Hantaan_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 9/150 98/10654 9.26188603358781e-6 6.914318880520008e-5 4.198979077238871e-5 6195/3551/6196/5594/1432/6197/5595/5600/9261 9 Hantaan_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 9/150 98/10654 9.26188603358781e-6 6.914318880520008e-5 4.198979077238871e-5 6195/3551/6196/5594/1432/6197/5595/5600/9261 9 Hantaan_virus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 9/150 103/10654 1.3915101822394288e-5 1.0286261543220877e-4 6.246717536368952e-5 5290/3667/2099/5594/5781/3630/2885/5595/207 9 Hantaan_virus R-HSA-5654741 Signaling by FGFR3 6/150 40/10654 1.8221358785775e-5 1.3210485119686873e-4 8.022561813575024e-5 5290/5594/5781/867/2885/5595 6 Hantaan_virus R-HSA-5674135 MAP2K and MAPK activation 6/150 40/10654 1.8221358785775e-5 1.3210485119686873e-4 8.022561813575024e-5 8649/7529/5594/5906/28956/5595 6 Hantaan_virus R-HSA-194315 Signaling by Rho GTPases 19/150 455/10654 2.039650928300435e-5 1.4646636189890745e-4 8.894718333941747e-5 5347/10971/7531/5747/7533/2810/5300/801/7534/5170/7529/5594/1432/2885/5595/5289/5600/1027/7532 19 Hantaan_virus R-HSA-5654743 Signaling by FGFR4 6/150 41/10654 2.10990491850745e-5 1.50081915901379e-4 9.114286390772004e-5 5290/5594/5781/867/2885/5595 6 Hantaan_virus R-HSA-186712 Regulation of beta-cell development 6/150 42/10654 2.4331950585874848e-5 1.707134101207984e-4 1.0367211140939171e-4 22938/2308/10000/208/3630/207 6 Hantaan_virus R-HSA-171007 p38MAPK events 4/150 13/10654 2.445231869104274e-5 1.707134101207984e-4 1.0367211140939171e-4 5898/1432/5600/9261 4 Hantaan_virus R-HSA-354192 Integrin alphaIIb beta3 signaling 5/150 27/10654 3.2534702976262735e-5 2.2301060040092821e-4 1.3543153870501713e-4 5747/5170/5906/2885/207 5 Hantaan_virus R-HSA-9006921 Integrin signaling 5/150 27/10654 3.2534702976262735e-5 2.2301060040092821e-4 1.3543153870501713e-4 5747/5170/5906/2885/207 5 Hantaan_virus R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 4/150 14/10654 3.385912020572548e-5 2.2794443424211617e-4 1.384277940741596e-4 5347/5861/5594/5595 4 Hantaan_virus R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 4/150 14/10654 3.385912020572548e-5 2.2794443424211617e-4 1.384277940741596e-4 10000/208/7157/207 4 Hantaan_virus R-HSA-5654732 Negative regulation of FGFR3 signaling 5/150 29/10654 4.678529060259092e-5 3.1217795676419073e-4 1.8958175511995387e-4 5594/5781/867/2885/5595 5 Hantaan_virus R-HSA-5625740 RHO GTPases activate PKNs 8/150 95/10654 5.532232140475086e-5 3.608101152343759e-4 2.1911545459577482e-4 10971/7531/7533/2810/7534/5170/7529/7532 8 Hantaan_virus R-HSA-69473 G2/M DNA damage checkpoint 8/150 95/10654 5.532232140475086e-5 3.608101152343759e-4 2.1911545459577482e-4 10971/7531/7533/2810/7534/7529/7157/7532 8 Hantaan_virus R-HSA-6804758 Regulation of TP53 Activity through Acetylation 5/150 30/10654 5.550924849759629e-5 3.608101152343759e-4 2.1911545459577482e-4 5300/10000/208/7157/207 5 Hantaan_virus R-HSA-5654733 Negative regulation of FGFR4 signaling 5/150 31/10654 6.543796809999435e-5 4.217113499777414e-4 2.561000101079401e-4 5594/5781/867/2885/5595 5 Hantaan_virus R-HSA-5654736 Signaling by FGFR1 6/150 50/10654 6.718643875035484e-5 4.2930995608277583e-4 2.607145482284064e-4 5290/5594/5781/867/2885/5595 6 Hantaan_virus R-HSA-450604 KSRP (KHSRP) binds and destabilizes mRNA 4/150 17/10654 7.789556991574533e-5 4.894438309705998e-4 2.9723309573113346e-4 7534/1432/5600/207 4 Hantaan_virus R-HSA-8934593 Regulation of RUNX1 Expression and Activity 4/150 17/10654 7.789556991574533e-5 4.894438309705998e-4 2.9723309573113346e-4 595/896/5781/894 4 Hantaan_virus R-HSA-76002 Platelet activation, signaling and aggregation 13/150 262/10654 8.154328939915974e-5 5.081292579088135e-4 3.085805209972552e-4 5290/5747/801/7534/5170/5594/1432/5781/5906/2885/3479/5595/207 13 Hantaan_virus R-HSA-5654726 Negative regulation of FGFR1 signaling 5/150 33/10654 8.935692111802962e-5 5.522550698606094e-4 3.3537757278984364e-4 5594/5781/867/2885/5595 5 Hantaan_virus R-HSA-2559583 Cellular Senescence 11/150 195/10654 9.469588109770654e-5 5.804934499810629e-4 3.5252638662817574e-4 6195/6196/5594/1432/6197/7157/5595/648/5600/1027/9261 11 Hantaan_virus R-HSA-5654727 Negative regulation of FGFR2 signaling 5/150 34/10654 1.035831897433735e-4 6.298526215040614e-4 3.82501592006515e-4 5594/5781/867/2885/5595 5 Hantaan_virus R-HSA-6806834 Signaling by MET 7/150 79/10654 1.183860145741232e-4 7.141044399111111e-4 4.336666639136302e-4 5290/5747/5781/5906/867/2885/10653 7 Hantaan_virus R-HSA-389513 CTLA4 inhibitory signaling 4/150 21/10654 1.8747895483152833e-4 0.0011218978725632727 6.813144975080603e-4 10000/208/5781/207 4 Hantaan_virus R-HSA-76009 Platelet Aggregation (Plug Formation) 5/150 39/10654 2.0253742886091477e-4 0.0012024663099301554 7.302426983381511e-4 5747/5170/5906/2885/207 5 Hantaan_virus R-HSA-453279 Mitotic G1-G1/S phases 9/150 149/10654 2.498662412112993e-4 0.00147186832713531 8.93847162227921e-4 595/7083/896/10000/208/894/1859/1027/207 9 Hantaan_virus R-HSA-5684996 MAPK1/MAPK3 signaling 12/150 255/10654 2.524210893279106e-4 0.0014753914833584851 8.95986730784505e-4 5747/801/8649/3667/7529/4763/5594/5781/5906/2885/28956/5595 12 Hantaan_virus R-HSA-8878166 Transcriptional regulation by RUNX2 8/150 121/10654 3.011052132021514e-4 0.0017464102365724779 0.001060573018161424 595/2099/10000/5594/208/2932/5595/207 8 Hantaan_virus R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 3/150 10/10654 3.053038502827743e-4 0.0017572450619329145 0.001067152871619179 23411/2308/2309 3 Hantaan_virus R-HSA-3371571 HSF1-dependent transactivation 4/150 24/10654 3.2210171654289076e-4 0.0018398840475253003 0.0011173384903999798 2475/84335/57521/64223 4 Hantaan_virus R-HSA-204005 COPII-mediated vesicle transport 6/150 68/10654 3.759110024125556e-4 0.0021311044798426083 0.0012941930039530012 5861/10802/9632/51693/11196/6399 6 Hantaan_virus R-HSA-392451 G beta:gamma signalling through PI3Kgamma 4/150 25/10654 3.7928234871028866e-4 0.0021341708278175943 0.0012960551585936807 5170/10000/208/207 4 Hantaan_virus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 6/150 69/10654 4.069935417807154e-4 0.0022731343000196996 0.001380445931186052 23411/7531/5594/2932/5595/9261 6 Hantaan_virus R-HSA-8854214 TBC/RABGAPs 5/150 46/10654 4.4552664776923356e-4 0.0024700521501323683 0.0015000316701208715 7249/5868/51256/27342/7248 5 Hantaan_virus R-HSA-6802957 Oncogenic MAPK signaling 6/150 71/10654 4.75161861680386e-4 0.0026151244066205184 0.0015881322307412054 801/7529/4763/5594/5906/5595 6 Hantaan_virus R-HSA-437239 Recycling pathway of L1 5/150 47/10654 4.929699730115429e-4 0.0026176011243007275 0.0015896363103040853 6195/6196/5594/6197/27330 5 Hantaan_virus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 5/150 47/10654 4.929699730115429e-4 0.0026176011243007275 0.0015896363103040853 801/7529/5594/5906/5595 5 Hantaan_virus R-HSA-6802949 Signaling by RAS mutants 5/150 47/10654 4.929699730115429e-4 0.0026176011243007275 0.0015896363103040853 801/7529/5594/5906/5595 5 Hantaan_virus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 5/150 47/10654 4.929699730115429e-4 0.0026176011243007275 0.0015896363103040853 801/7529/5594/5906/5595 5 Hantaan_virus R-HSA-9649948 Signaling downstream of RAS mutants 5/150 47/10654 4.929699730115429e-4 0.0026176011243007275 0.0015896363103040853 801/7529/5594/5906/5595 5 Hantaan_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 5/150 48/10654 5.441177390287104e-4 0.002868984442151382 0.001742298244221487 5290/7534/5781/867/2885 5 Hantaan_virus R-HSA-5654738 Signaling by FGFR2 6/150 73/10654 5.51916500105876e-4 0.0028898961186099342 0.0017549976428805267 5290/5594/5781/867/2885/5595 6 Hantaan_virus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 5/150 49/10654 5.991524652014345e-4 0.0031155928190474596 0.0018920604164255823 2810/10498/7157/1027/10769 5 Hantaan_virus R-HSA-1227986 Signaling by ERBB2 5/150 50/10654 6.58259801473777e-4 0.0033995060980221087 0.002064477387462819 5290/10000/208/2885/207 5 Hantaan_virus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 3/150 13/10654 7.053895630294067e-4 0.0035488367450307854 0.0021551640152008816 10000/208/207 3 Hantaan_virus R-HSA-203615 eNOS activation 3/150 13/10654 7.053895630294067e-4 0.0035488367450307854 0.0021551640152008816 857/801/207 3 Hantaan_virus R-HSA-879415 Advanced glycosylation endproduct receptor signaling 3/150 13/10654 7.053895630294067e-4 0.0035488367450307854 0.0021551640152008816 5594/5589/5595 3 Hantaan_virus R-HSA-112316 Neuronal System 15/150 413/10654 7.060020049795993e-4 0.0035488367450307854 0.0021551640152008816 51422/6195/5564/6196/801/5170/5563/5565/5594/5571/6197/5562/5595/53632/27330 15 Hantaan_virus R-HSA-5673001 RAF/MAP kinase cascade 11/150 249/10654 7.766420808040614e-4 0.0038780670789818695 0.0023551014649687467 5747/801/8649/3667/7529/4763/5594/5906/2885/28956/5595 11 Hantaan_virus R-HSA-163685 Integration of energy metabolism 7/150 108/10654 8.112809979708251e-4 0.004024380739934224 0.002443955914939812 51422/5563/5565/6794/3630/5906/9370 7 Hantaan_virus R-HSA-200425 Import of palmitoyl-CoA into the mitochondrial matrix 3/150 14/10654 8.885342292540465e-4 0.004378789600376151 0.0026591839678397674 51422/5563/5565 3 Hantaan_virus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 4/150 32/10654 9.988253256475953e-4 0.0048588019066986244 0.0029506894170234564 4087/4088/22938/904 4 Hantaan_virus R-HSA-397795 G-protein beta:gamma signalling 4/150 32/10654 9.988253256475953e-4 0.0048588019066986244 0.0029506894170234564 5170/10000/208/207 4 Hantaan_virus R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF) 5/150 55/10654 0.0010215844259206148 0.004937658058616305 0.002998577768390468 6720/5469/10802/9632/10498 5 Hendra_virus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 256/1591 309/10654 4.1550869761188734e-163 5.497180069405269e-160 3.074764362327966e-160 8454/9354/57154/197131/23352/26224/8945/10293/51088/140460/79754/6737/8065/64410/127544/114088/11065/285231/221687/9666/84937/57531/142678/55070/84708/246184/146330/55819/51320/93611/7319/54850/142686/8916/79791/26046/151636/7321/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/8697/7320/26235/10477/9817/10193/148581/9039/223082/92912/154881/140739/25897/6500/6478/150726/390594/10533/81559/144699/140462/26259/57674/51130/53339/154214/7336/200845/79876/26263/64750/51619/6477/9690/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/9604/9978/22888/23304/7317/80196/114907/140456/64718/54926/4008/7335/84861/11059/55236/899/84085/55958/54620/4734/84078/7337/26272/84676/27252/51444/7704/8651/3093/26118/222235/51433/25831/7322/5715/64219/10489/23327/9867/26249/140458/55905/55336/26270/143279/51465/63893/89122/6502/23291/118424/10616/5698/27246/89910/55521/25898/9903/201456/55294/26190/55008/7328/79654/10422/84727/135892/7428/5702/22954/8453/401036/83737/51529/9040/90933/140461/7324/63891/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/6233/90135/56658/9870/51434/6468/26267/142685/4012/25847/90025/7327/10425/25793/51343/7311/26091/23295/6047/84541/7318/23194/51666/90293/131405/55175/55284/868/54461/9320/136371/80204/26232/29882/57520/26234/127247/27338/7334/92591/5930/11275/55182/84961/4591/23014/29116/26268/92369/115290/90678/51725/140459/5696/997/23608/51676/55585/64320/51132/84261/7325/57542/9820/55658/7314/996/10324/283807/140691 256 Hendra_virus R-HSA-983169 Class I MHC mediated antigen processing & presentation 281/1591 371/10654 6.260998810878377e-160 4.141650713396046e-157 2.3165695600249994e-157 8454/9354/23643/57154/1147/3135/197131/23352/26224/8945/10293/51088/140460/79754/6737/8065/64410/127544/114088/11065/285231/221687/9666/84937/57531/142678/55070/84708/246184/146330/55819/51320/93611/7319/54850/142686/8916/79791/26046/151636/3107/7321/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/8697/7320/26235/10477/10802/9817/10193/6890/148581/9039/223082/92912/154881/140739/25897/6500/6478/150726/390594/10533/81559/144699/140462/26259/57674/51130/10333/7099/53339/8517/154214/7336/200845/4615/79876/26263/64750/51619/6477/9690/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/9604/9978/22888/23304/7317/80196/114907/140456/64718/54926/4008/7335/84861/7096/11059/55236/899/84085/55958/54620/4734/84078/7337/26272/84676/27252/51444/7704/8651/3106/3093/26118/222235/51433/25831/7322/5715/64219/10489/23327/9867/26249/140458/55905/55336/26270/143279/51465/63893/89122/6502/23291/118424/10616/929/5698/27246/89910/114609/55521/25898/9903/201456/55294/26190/55008/2923/7328/79654/10422/84727/135892/7428/5702/22954/8453/401036/83737/51529/9040/695/90933/140461/7324/63891/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/6233/90135/56658/9870/51434/6468/26267/948/142685/4012/25847/90025/7327/3685/10425/25793/51343/7311/26091/23295/6047/84541/3133/7318/23194/51666/90293/131405/55175/55284/3134/868/54461/9320/136371/80204/26232/29882/57520/26234/127247/27338/7334/92591/5930/11275/55182/7097/84961/4591/3551/23014/29116/26268/92369/1536/115290/90678/51725/140459/3105/5696/997/23608/51676/55585/64320/51132/84261/7325/57542/9820/55658/7314/996/4360/10324/283807/140691 281 Hendra_virus R-HSA-449147 Signaling by Interleukins 279/1591 461/10654 1.1645162911374982e-118 5.135516843916366e-116 2.872473518139162e-116 5295/729230/8454/6095/3605/3557/7124/1147/2308/54014/834/1052/10148/3725/7291/5777/8945/1326/596/9655/5601/3562/351/6464/2208/3592/5290/3566/1437/3667/4790/6885/6597/2309/90865/5291/5604/64109/3561/11213/3587/5783/7412/6351/3578/7184/10392/27178/8767/356/3593/3589/6775/207/50616/5292/5451/3684/9021/1849/7422/29110/3553/2625/1230/1439/5594/8878/3595/54472/6624/4582/2919/6500/3082/5743/3091/3568/941/23118/10538/4318/6367/3726/4312/3383/58480/11009/6097/4478/6349/8517/6657/1438/6778/53833/3576/4615/3581/3313/332/3662/3597/6776/5528/3688/2357/1436/4313/7316/3565/4985/3934/9978/2920/3560/3976/6352/50615/6774/4314/1435/7335/5970/1441/4792/3055/5443/6850/1026/6348/9261/59307/3718/1440/3627/7133/3606/177/6772/8651/8809/4609/3146/149233/6364/5715/5519/64127/8503/7132/4988/1901/3552/1432/867/79923/3567/6950/3558/4067/3717/23291/4088/3636/2247/598/836/5698/3320/29949/4843/2335/2534/3656/595/9466/5771/3458/10454/6288/5702/998/7157/942/3654/3563/7189/163702/112744/6285/5609/6233/2885/7525/1398/58985/7006/948/6844/3716/85480/7409/51135/8660/1385/2353/604/282618/7311/53832/3594/1154/6363/1270/50604/6347/3932/3575/7076/5293/5518/2185/302/1386/5296/7040/6935/3687/3588/51561/3570/6197/8835/5599/5600/7431/6777/7334/6356/3600/5008/3977/3312/1399/3559/3574/3929/3551/246778/55801/6773/7850/7297/6416/5781/3569/3162/1489/5062/4170/3689/1234/5696/3601/3586/4791/5724/3554/4692/7314/3572/3596/5595/5515/59067/257397/3556/5516 279 Hendra_virus R-HSA-8951664 Neddylation 165/1591 234/10654 3.061578681702126e-84 1.0126171489729782e-81 5.663920561148933e-82 8454/9318/51397/26224/54165/8945/56995/23412/51088/9655/140460/79754/8065/64410/149951/29099/285231/23038/146330/25879/93611/54850/142686/55884/79791/7321/51665/9616/122769/9021/4738/26235/9817/9039/154881/140739/6500/150726/3091/390594/144699/140462/28952/26259/51130/53339/28991/200845/332/26263/140825/8452/8450/7323/9306/10517/89890/142689/7316/9978/114907/140456/4008/84861/64708/899/84085/55958/54620/84078/55527/26272/27252/7704/26118/222235/10980/7322/5715/122416/10489/26249/140458/55336/26270/6502/7347/23291/170622/90864/55832/5698/1642/10920/9903/201456/55294/26190/84727/10987/7428/5702/8453/123879/401036/9040/140461/79176/80176/8139/23142/126433/10116/6233/90135/6468/2873/26267/142685/25793/7311/1154/84541/23194/83987/51666/2034/90293/55175/8533/54461/136371/80204/26232/8835/26234/127247/8883/92591/11275/51122/84961/54939/23014/26268/92369/115290/54951/51725/140459/55208/84259/5696/51676/84261/150684/50813/57542/9820/7314/51138/10324/8451/56929/283807 165 Hendra_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 100/1591 108/10654 1.8230212207614087e-73 4.823714150134688e-71 2.6980714067268853e-71 5295/6095/3605/7124/2308/1052/7291/596/9655/2208/3592/3566/2309/3561/7412/7184/356/3593/207/5292/5451/3684/9021/7422/3553/2625/6624/4582/3082/5743/3091/10538/4318/6367/3726/4312/3383/58480/6097/6657/6778/3576/332/3662/3597/3688/4313/3565/4985/3934/3976/6774/4314/5443/1026/3718/7133/3606/6772/8651/4609/149233/4988/1901/3552/79923/3717/2247/598/3320/4843/2335/595/6288/7157/112744/948/3716/2353/604/6347/7076/7040/6935/3687/51561/3570/7431/6356/5008/3312/3929/7297/3569/3162/4170/3689/3586/4692/3596 100 Hendra_virus R-HSA-168898 Toll-like Receptor Cascades 114/1591 155/10654 2.503199331552822e-61 5.519554526073972e-59 3.0872791755818137e-59 54106/8454/23643/1147/3665/3725/11035/8945/4064/1326/10695/5601/351/81793/4790/6885/5604/11213/7184/7321/8737/10392/653509/8767/5336/3684/1849/29110/5594/6271/1785/4214/6500/330/51295/23118/6280/10333/841/7099/8517/4615/7098/7100/338/5528/7323/7316/7335/5970/4792/7096/9261/59307/6279/177/8651/26052/3146/7322/5519/64127/1432/329/23291/2244/929/114609/3656/10454/6288/3661/695/3654/7189/6285/5609/6233/51311/10010/948/2266/51135/1385/81622/2353/7311/1759/5518/2243/7187/1386/8772/9641/6197/5599/353376/5600/7334/7097/3929/3551/6416/5781/3689/9450/4791/51284/7314/5595/5515/148022/257397/5516 114 Hendra_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 98/1591 129/10654 5.142601370144438e-55 9.719516589572989e-53 5.436464305581263e-53 8454/23643/1147/3665/3725/11035/8945/4064/1326/5601/351/4790/6885/5604/11213/7321/8737/10392/653509/8767/5336/3684/1849/29110/5594/1785/4214/6500/330/51295/23118/10333/841/7099/8517/4615/5528/7323/7316/7335/5970/4792/7096/9261/59307/177/8651/26052/3146/7322/5519/64127/1432/329/23291/929/114609/3656/10454/6288/3661/695/3654/7189/6285/5609/6233/10010/948/51135/1385/2353/7311/1759/5518/7187/1386/8772/9641/6197/5599/353376/5600/7334/7097/3929/3551/6416/5781/3689/9450/4791/7314/5595/5515/148022/257397/5516 98 Hendra_virus R-HSA-909733 Interferon alpha/beta signaling 67/1591 69/10654 2.422203228834102e-53 4.0057185896843957e-51 2.2405379866715442e-51 3135/3443/3665/5777/3441/51447/10379/5770/3455/3107/10410/9021/54739/4600/9636/2537/11274/8638/3449/2634/3444/3662/3394/3663/8519/3664/103/3434/6772/8651/3433/3659/3106/6041/1958/25939/4939/6059/3451/3448/3440/3454/3661/3669/3439/4599/684/3716/3133/3429/10581/3134/3452/4940/91543/3437/3456/6773/4938/7297/5781/3430/3105/5696/3660/3446/3445 67 Hendra_virus R-HSA-913531 Interferon Signaling 115/1591 199/10654 3.9700462307207325e-45 5.835967959159477e-43 3.2642602341481583e-43 3135/3443/3665/818/3460/201626/5777/815/3441/6737/51447/10379/5335/115362/960/5770/3455/7412/3107/10410/2316/817/2633/9021/85363/54739/9830/4600/3123/9636/2537/3383/11274/8638/3449/25820/7706/2634/3444/3662/7316/3122/3394/3663/8519/3664/103/4734/3434/3113/6772/8651/3433/3659/3106/23586/6041/3459/1958/25939/4939/6059/3451/3717/3448/3440/5771/3458/3454/816/3661/3669/10346/7324/3836/9246/5371/3439/51191/4599/6233/5580/684/3716/7311/81603/3133/7318/3429/5610/10581/3134/5300/3452/3127/4940/91543/3437/7334/3456/6773/4938/7297/5781/4261/3430/3105/5696/3660/5724/3446/7314/3445/5595/8554 115 Hendra_virus R-HSA-166166 MyD88-independent TLR4 cascade 75/1591 99/10654 3.960934056103981e-42 4.763923414750515e-40 2.6646283650154056e-40 8454/23643/1147/3665/3725/11035/8945/1326/5601/351/4790/6885/5604/7321/8737/10392/8767/1849/29110/5594/6500/330/23118/841/7099/8517/5528/7323/7316/7335/5970/4792/9261/177/3146/7322/5519/64127/1432/329/23291/929/3656/10454/6288/3661/3654/7189/6285/5609/6233/10010/1385/2353/7311/5518/7187/1386/8772/9641/6197/5599/353376/5600/7334/3551/6416/5781/4791/7314/5595/5515/148022/257397/5516 75 Hendra_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 75/1591 99/10654 3.960934056103981e-42 4.763923414750515e-40 2.6646283650154056e-40 8454/23643/1147/3665/3725/11035/8945/1326/5601/351/4790/6885/5604/7321/8737/10392/8767/1849/29110/5594/6500/330/23118/841/7099/8517/5528/7323/7316/7335/5970/4792/9261/177/3146/7322/5519/64127/1432/329/23291/929/3656/10454/6288/3661/3654/7189/6285/5609/6233/10010/1385/2353/7311/5518/7187/1386/8772/9641/6197/5599/353376/5600/7334/3551/6416/5781/4791/7314/5595/5515/148022/257397/5516 75 Hendra_virus R-HSA-5663202 Diseases of signal transduction 162/1591 377/10654 6.669235169959562e-41 7.352831774880417e-39 4.112695021475063e-39 5295/8454/1147/2308/27044/818/5170/815/8805/1839/4893/11052/6464/26127/8841/5290/3667/5335/142678/2309/5291/5604/1499/2065/10018/5525/892/842/55750/3815/572/5430/5526/23462/817/207/3674/1452/55534/5594/3280/4303/84335/613/1027/8074/7249/6500/409/3082/84441/941/10533/10013/23385/2064/6199/10046/2260/9208/6776/5528/2100/7316/9978/1950/6774/2263/4233/9759/1026/55615/6772/6714/2099/5605/4609/7415/64223/10014/5715/5519/8850/8503/399687/2932/2261/867/1387/5437/5159/3717/4088/2247/2244/3164/5698/10000/3320/3084/2335/2534/2033/55294/5728/5529/1445/816/5702/3066/3065/2066/5894/4087/942/208/9794/6233/5527/2885/79109/2475/2266/7409/8660/1385/7048/7311/3932/2931/5293/5518/5155/2243/1956/60/4254/118788/5296/7040/3845/388585/6777/3265/3516/369/801/5781/5696/7750/11140/5245/5156/940/7314/1523/5879/253260/5595/4193/5515/5516 162 Hendra_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 71/1591 94/10654 8.825680040213598e-40 8.981826687078916e-38 5.023848638275433e-38 8454/1147/3665/3725/11035/8945/1326/5601/351/4790/6885/5604/7321/8737/10392/8767/1849/29110/5594/6500/330/23118/841/8517/7098/5528/7323/7316/7335/5970/4792/9261/177/3146/7322/5519/64127/1432/329/23291/3656/10454/6288/3661/3654/7189/6285/5609/6233/10010/1385/2353/7311/5518/7187/1386/8772/9641/6197/5599/5600/7334/3551/6416/4791/7314/5595/5515/148022/257397/5516 71 Hendra_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 70/1591 95/10654 5.077077268280201e-38 4.4779821506231375e-36 2.5046914523515656e-36 8454/23643/1147/3725/8945/1326/5601/351/4790/6885/5604/11213/10392/8767/1849/5594/4214/6500/51295/23118/10333/7099/8517/4615/5528/7316/7335/5970/4792/7096/9261/59307/177/8651/3146/5519/64127/1432/23291/929/114609/3656/10454/6288/695/3654/7189/6285/5609/6233/948/51135/1385/2353/7311/5518/1386/6197/5599/5600/7334/7097/3551/6416/4791/7314/5595/5515/257397/5516 70 Hendra_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 70/1591 95/10654 5.077077268280201e-38 4.4779821506231375e-36 2.5046914523515656e-36 8454/23643/1147/3725/8945/1326/5601/351/4790/6885/5604/11213/10392/8767/1849/5594/4214/6500/51295/23118/10333/7099/8517/4615/5528/7316/7335/5970/4792/7096/9261/59307/177/8651/3146/5519/64127/1432/23291/929/114609/3656/10454/6288/695/3654/7189/6285/5609/6233/948/51135/1385/2353/7311/5518/1386/6197/5599/5600/7334/7097/3551/6416/4791/7314/5595/5515/257397/5516 70 Hendra_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 71/1591 98/10654 9.852125855404927e-38 7.667272062765128e-36 4.288572431176262e-36 8454/23643/1147/3725/8945/1326/5601/351/4790/6885/5604/11213/10392/653509/8767/1849/5594/4214/6500/51295/23118/10333/7099/8517/4615/5528/7316/7335/5970/4792/7096/9261/59307/177/8651/3146/5519/64127/1432/23291/929/114609/3656/10454/6288/695/3654/7189/6285/5609/6233/948/51135/1385/2353/7311/5518/1386/6197/5599/5600/7334/7097/3551/6416/4791/7314/5595/5515/257397/5516 71 Hendra_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 71/1591 98/10654 9.852125855404927e-38 7.667272062765128e-36 4.288572431176262e-36 8454/23643/1147/3725/8945/1326/5601/351/4790/6885/5604/11213/10392/653509/8767/1849/5594/4214/6500/51295/23118/10333/7099/8517/4615/5528/7316/7335/5970/4792/7096/9261/59307/177/8651/3146/5519/64127/1432/23291/929/114609/3656/10454/6288/695/3654/7189/6285/5609/6233/948/51135/1385/2353/7311/5518/1386/6197/5599/5600/7334/7097/3551/6416/4791/7314/5595/5515/257397/5516 71 Hendra_virus R-HSA-1257604 PIP3 activates AKT signaling 125/1591 264/10654 7.704197125941855e-37 5.662584887567264e-35 3.1672810406649844e-35 5295/1147/2308/5170/3725/23396/3643/1839/8841/5290/3667/2309/90865/23035/5291/5468/2065/5525/1822/23186/842/3815/572/23239/2146/5526/10273/207/6045/5594/4303/84335/1027/8074/7249/3082/1460/941/2064/57761/6199/2260/4615/5528/2100/7316/1950/2263/4233/1026/55615/4734/6714/2099/57167/64223/10014/5715/5519/8503/1958/2932/2261/5159/2247/3164/5698/10000/3084/2534/23512/5728/6009/5529/6615/3630/5702/3066/3065/7157/2066/23028/8975/942/3654/7189/5371/208/6233/5527/2885/79109/2475/7409/51135/8660/1385/7311/3932/2931/5293/5518/5155/1386/1956/4254/118788/5296/4343/117145/648/5781/57521/5696/23608/5156/940/7314/5879/253260/5595/4193/5515/3556/5516 125 Hendra_virus R-HSA-9006925 Intracellular signaling by second messengers 135/1591 305/10654 8.819459716885148e-36 6.141129055494238e-34 3.4349474686815846e-34 5295/1147/2308/818/5170/3725/23396/815/3643/1839/8841/5290/3667/5335/2309/90865/23035/5291/5468/2065/5525/1822/23186/842/3815/572/23239/2146/5526/817/10273/207/6045/5578/5594/4303/84335/1027/8074/7249/3082/1460/941/2064/57761/6199/2260/4615/5528/2100/7316/1950/2263/4233/1026/55615/4734/10768/6714/2099/57167/64223/10014/5715/5519/8503/1958/2932/2261/5159/2247/3164/5698/10000/3084/2534/23512/5728/6009/5529/6615/816/3630/5702/3066/3065/7157/2066/23028/8975/942/3654/7189/5371/208/6233/5527/2885/79109/5580/2475/7409/51135/8660/1385/7311/3932/2931/5293/5518/5155/1386/1956/4254/118788/5296/5581/4343/117145/648/801/5781/57521/5696/23608/5156/940/7314/5879/253260/5595/4193/5515/3556/5516 135 Hendra_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 178/1591 473/10654 1.1918661724611468e-35 7.884194730830488e-34 4.409904838106244e-34 5295/54106/5170/4908/5777/627/1173/3643/5590/1839/4893/8065/6464/857/5290/2670/3667/85440/5335/558/5241/5579/5770/4915/5291/5604/1499/2065/5747/4690/526/3815/5430/10273/207/10019/1849/7422/5578/5594/10193/2322/1785/8074/3315/3082/2241/9101/10817/23118/51741/23385/4318/2064/57761/5921/6778/2260/348/6776/5528/9306/3688/7316/1950/5753/5140/9047/6774/2263/11059/4233/9261/55615/4734/10768/10413/6772/6714/2099/8651/5605/26052/64223/1447/5519/3673/8503/1432/2261/867/5437/5159/4670/4067/3717/4909/2247/4914/529/10000/9146/3320/3084/2335/2534/4846/4803/8471/5771/1445/5603/3630/998/2066/83737/3914/3913/3925/6285/208/1742/6233/2885/7525/1398/79109/7410/7006/5580/2475/7409/8660/1385/3685/163/7311/3932/3479/1759/5518/5155/2185/3791/387/1956/60/4254/5296/5581/117145/6197/3845/5600/6777/3265/1399/6300/528/801/1020/5781/1536/5062/3480/10252/11140/53916/4916/5156/7314/5879/253260/5595/5515/6387/5516/2242 178 Hendra_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 67/1591 93/10654 2.0605743402551033e-35 1.2391544782534097e-33 6.931022780858075e-34 54106/8454/23643/1147/3665/3725/8945/1326/5601/351/4790/6885/5604/10392/8767/1849/5594/4214/6500/51295/23118/7099/8517/4615/5528/7316/7335/5970/4792/9261/177/3146/5519/64127/1432/23291/929/3656/10454/6288/3654/7189/6285/5609/6233/51311/51135/1385/2353/7311/5518/1386/6197/5599/353376/5600/7334/3551/6416/4791/51284/7314/5595/5515/148022/257397/5516 67 Hendra_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 67/1591 93/10654 2.0605743402551033e-35 1.2391544782534097e-33 6.931022780858075e-34 54106/8454/23643/1147/3665/3725/8945/1326/5601/351/4790/6885/5604/10392/8767/1849/5594/4214/6500/51295/23118/7099/8517/4615/5528/7316/7335/5970/4792/9261/177/3146/5519/64127/1432/23291/929/3656/10454/6288/3654/7189/6285/5609/6233/51311/51135/1385/2353/7311/5518/1386/6197/5599/353376/5600/7334/3551/6416/4791/51284/7314/5595/5515/148022/257397/5516 67 Hendra_virus R-HSA-6783783 Interleukin-10 signaling 45/1591 47/10654 3.1984443915815356e-35 1.8398008391575527e-33 1.0290647172914506e-33 729230/3557/7124/2208/3592/1437/3587/6351/3593/3553/1230/2919/5743/941/6367/3383/6349/3576/2357/2920/3976/6352/6774/1435/6348/1440/3627/7133/3606/6364/7132/3552/942/3716/6363/6347/7076/3588/7850/7297/3569/1234/3586/5724/3554 45 Hendra_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 66/1591 92/10654 1.0292462703413741e-34 5.673720065256825e-33 3.17350933355257e-33 54106/8454/23643/1147/3725/8945/1326/5601/351/4790/6885/5604/10392/8767/1849/5594/4214/6500/51295/23118/7099/8517/4615/5528/7316/7335/5970/4792/9261/177/3146/5519/64127/1432/23291/929/3656/10454/6288/3654/7189/6285/5609/6233/51311/51135/1385/2353/7311/5518/1386/6197/5599/353376/5600/7334/3551/6416/4791/51284/7314/5595/5515/148022/257397/5516 66 Hendra_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 67/1591 97/10654 1.4115510474519741e-33 7.469928143115847e-32 4.1781911004578437e-32 54106/8454/23643/1147/3665/3725/8945/1326/5601/351/4790/6885/5604/10392/8767/1849/5594/4214/6500/51295/23118/7099/8517/4615/5528/7316/7335/5970/4792/9261/177/3146/5519/64127/1432/23291/929/3656/10454/6288/3654/7189/6285/5609/6233/51311/51135/1385/2353/7311/5518/1386/6197/5599/353376/5600/7334/3551/6416/4791/51284/7314/5595/5515/148022/257397/5516 67 Hendra_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 59/1591 78/10654 2.7107232854313154e-33 1.3793411179329349e-031 7.715135504689128e-32 1147/3443/3665/3441/351/7186/4790/7321/8737/29110/57506/4214/9636/54476/3449/841/7706/8517/3444/7323/7316/5970/4792/177/3093/3146/23586/7322/7128/1387/3451/3448/2033/64135/3440/6288/83737/3661/9246/7189/3439/6285/51191/6233/10010/7311/7318/7187/8772/5300/3452/9641/1540/3551/3456/4791/3446/7314/3445 59 Hendra_virus R-HSA-9009391 Extra-nuclear estrogen signaling 57/1591 77/10654 2.4311572771045007e-31 1.1912670657812053e-29 6.663171796508632e-30 5295/2788/5170/596/5590/1839/4893/6464/857/5290/54331/4316/2309/5747/59345/207/5594/1027/3315/10681/51764/94235/4318/2100/4313/1950/55970/4314/2792/6714/2099/8503/2793/10000/3320/2785/4846/595/2783/2784/2782/2786/208/7514/1385/2353/1956/5296/3845/3276/3265/801/3480/2791/5595/2790/2787 57 Hendra_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 60/1591 85/10654 5.078708361658484e-31 2.2397103874913916e-29 1.2527480625424261e-29 8454/1147/3725/8945/1326/5601/351/81793/4790/6885/5604/10392/8767/1849/5594/4214/6500/51295/23118/8517/4615/7100/5528/7316/7335/5970/4792/9261/177/3146/5519/64127/1432/23291/3656/10454/6288/3654/7189/6285/5609/6233/51135/1385/2353/7311/5518/1386/6197/5599/5600/7334/3551/6416/4791/7314/5595/5515/257397/5516 60 Hendra_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 60/1591 85/10654 5.078708361658484e-31 2.2397103874913916e-29 1.2527480625424261e-29 8454/1147/3725/8945/1326/5601/351/81793/4790/6885/5604/10392/8767/1849/5594/4214/6500/51295/23118/8517/4615/7100/5528/7316/7335/5970/4792/9261/177/3146/5519/64127/1432/23291/3656/10454/6288/3654/7189/6285/5609/6233/51135/1385/2353/7311/5518/1386/6197/5599/5600/7334/3551/6416/4791/7314/5595/5515/257397/5516 60 Hendra_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 60/1591 85/10654 5.078708361658484e-31 2.2397103874913916e-29 1.2527480625424261e-29 8454/1147/3725/8945/1326/5601/351/81793/4790/6885/5604/10392/8767/1849/5594/4214/6500/51295/23118/8517/4615/7100/5528/7316/7335/5970/4792/9261/177/3146/5519/64127/1432/23291/3656/10454/6288/3654/7189/6285/5609/6233/51135/1385/2353/7311/5518/1386/6197/5599/5600/7334/3551/6416/4791/7314/5595/5515/257397/5516 60 Hendra_virus R-HSA-2219528 PI3K/AKT Signaling in Cancer 66/1591 101/10654 7.662334698876448e-31 3.27008671181082e-29 1.8290734442479263e-29 5295/1147/2308/5170/1839/5290/3667/2309/5291/2065/842/3815/572/207/4303/84335/1027/8074/7249/3082/941/2064/6199/2260/2100/1950/2263/4233/1026/55615/6714/2099/64223/8503/2932/2261/5159/2247/3164/10000/3084/2534/5728/2066/942/208/2885/79109/2475/7409/8660/1385/3932/2931/5293/5155/1956/4254/118788/5296/5781/5156/940/5879/253260/4193 66 Hendra_virus R-HSA-199418 Negative regulation of the PI3K/AKT network 68/1591 110/10654 1.4836785127025563e-29 6.134083350954631e-28 3.431006560624661e-28 5295/23396/3643/1839/5290/3667/90865/23035/5291/2065/5525/3815/23239/5526/207/5594/8074/3082/941/2064/57761/2260/4615/5528/2100/1950/2263/4233/6714/2099/5519/8503/2261/5159/2247/10000/3084/2534/5728/5529/3630/2066/942/3654/7189/208/5527/2885/7409/51135/8660/3932/5293/5518/5155/1956/4254/118788/5296/117145/5781/5156/940/5879/5595/5515/3556/5516 68 Hendra_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 41/1591 48/10654 2.226448492773333e-27 8.926034411936726e-26 4.9926420747038376e-26 5295/5777/3562/6464/5290/1437/5291/3561/1439/3568/1438/6776/7316/3560/3055/6850/3718/8503/867/3567/3558/4067/3717/3636/2534/3563/6233/2885/7525/1398/7006/3716/7409/7311/5293/5296/6777/1399/3559/5781/7314 41 Hendra_virus R-HSA-388841 Costimulation by the CD28 family 50/1591 70/10654 1.9669133931405084e-26 7.653607115073214e-25 4.280929149776401e-25 5295/5170/5777/1326/5290/5525/5526/207/5133/3123/941/57761/919/5528/3122/9020/55615/3113/6714/64223/5519/8503/29126/4067/10000/2534/5529/1445/998/942/208/5527/2885/7525/79109/2475/7409/3932/5518/5296/3127/117145/5781/5062/1493/940/5879/253260/5515/5516 50 Hendra_virus R-HSA-451927 Interleukin-2 family signaling 38/1591 44/10654 7.967263918561365e-26 3.0116257612161957e-24 1.6845072284958318e-24 5295/5777/3562/6464/5290/1437/5291/3561/3578/6775/1439/3568/1438/3581/6776/3560/50615/6774/6850/3718/6772/8503/3567/3558/3717/3636/3563/2885/3716/3932/5293/2185/5296/6777/3600/3559/3601/59067 38 Hendra_virus R-HSA-9607240 FLT3 Signaling 109/1591 267/10654 2.1252884499952096e-25 7.810435053732395e-24 4.368648480545708e-24 5295/54106/818/5170/815/1839/2674/3562/4893/6464/6711/5290/1437/3667/1844/5291/5604/2065/3561/5525/5747/3815/5526/817/3674/1849/7010/1439/5594/2322/8074/409/3082/3568/10817/2064/57761/5921/1438/2260/8452/6776/5528/7316/9978/1950/3560/5140/2263/4233/3055/84078/3718/6714/5605/5715/6710/5519/2261/5159/3567/3558/3717/2247/2244/5698/3084/2335/2534/5529/1445/816/5702/2066/5894/3563/5979/208/1742/6233/5527/2885/6709/3716/2266/8660/7311/5518/5155/2243/1956/60/4254/5296/117145/3845/6777/3265/3559/369/801/5781/5696/5245/5156/7314/5595/5515/5516 109 Hendra_virus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 61/1591 103/10654 3.437920162067156e-25 1.2292887498418508e-23 6.875840324134312e-24 5295/23396/3643/1839/5290/3667/90865/5291/2065/5525/3815/5526/207/5594/8074/3082/941/2064/2260/4615/5528/2100/1950/2263/4233/6714/2099/5519/8503/2261/5159/2247/3084/2534/5529/3630/2066/942/3654/7189/5527/2885/7409/51135/8660/3932/5293/5518/5155/1956/4254/118788/5296/5781/5156/940/5879/5595/5515/3556/5516 61 Hendra_virus R-HSA-450294 MAP kinase activation 46/1591 64/10654 1.32552604597608e-24 4.614923575858826e-23 2.581287563216577e-23 8454/1147/3725/8945/1326/5601/4790/6885/5604/10392/8767/1849/5594/6500/23118/8517/5528/7316/7335/9261/5519/64127/1432/23291/3656/10454/3654/7189/5609/6233/1385/2353/7311/5518/1386/6197/5599/5600/7334/3551/6416/7314/5595/5515/257397/5516 46 Hendra_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 42/1591 55/10654 2.5465659264928405e-24 8.638735181410327e-23 4.8319456041146206e-23 1147/834/596/351/4790/6885/842/10392/8767/10910/58484/7295/330/23118/841/8517/7316/7335/5970/64127/7128/1432/329/598/3656/5603/10454/83737/3654/7189/6233/3326/7311/114548/5600/7334/1540/3551/6300/4791/7314/257397 42 Hendra_virus R-HSA-5683057 MAPK family signaling cascades 114/1591 294/10654 2.9554901307442305e-24 9.775283607436543e-23 5.467656741876826e-23 2308/818/3725/815/1839/2674/3562/4893/6464/6711/1437/3667/2309/1844/5604/2065/3561/5525/5747/3815/5526/817/3674/1849/7010/1439/5594/2322/8074/3315/409/3082/3568/10817/2064/5921/1438/2260/5596/8452/5528/7316/9978/1950/3560/2263/4233/5597/84078/3718/6714/5605/4609/5715/6710/5519/2261/5159/3567/3558/3717/2247/2244/5698/3084/2335/2534/5529/1445/816/5702/998/2066/5894/896/3563/5979/1742/6233/5527/2885/6709/3716/2266/8660/7514/7311/5518/5155/2243/1956/60/4254/4343/3570/3845/3265/3559/369/801/7297/5781/8202/3569/5062/5696/5245/5156/7314/3572/5879/5595/5515/5516 114 Hendra_virus R-HSA-877300 Interferon gamma signaling 56/1591 92/10654 4.582689441458887e-24 1.4787556417195383e-22 8.271195577267259e-23 3135/3665/818/3460/5777/815/6737/10379/115362/960/5770/7412/3107/817/2633/9021/85363/9830/3123/3383/8638/7706/2634/3662/3122/3394/3663/3664/3113/6772/8651/3659/3106/3459/4939/3717/5771/3458/816/3661/10346/5371/5580/3716/81603/3133/3134/3127/4940/4938/5781/4261/3105/3660/5724/8554 56 Hendra_virus R-HSA-448424 Interleukin-17 signaling 48/1591 72/10654 2.466198078221668e-23 7.768523946398254e-22 4.345206137819129e-22 8454/3605/1147/3725/8945/1326/5601/4790/6885/5604/10392/8767/1849/5594/6500/23118/8517/5528/7316/7335/9261/5519/64127/1432/23291/3656/10454/3654/7189/112744/5609/6233/1385/2353/7311/5518/1386/6197/5599/5600/7334/3551/6416/7314/5595/5515/257397/5516 48 Hendra_virus R-HSA-389356 CD28 co-stimulation 30/1591 33/10654 4.571444724090559e-22 1.4065165976678627e-20 7.867137432155845e-21 5295/5170/1326/5290/207/941/57761/9020/55615/6714/64223/8503/4067/10000/2534/998/942/208/2885/7525/79109/2475/7409/3932/5296/117145/5062/940/5879/253260 30 Hendra_virus R-HSA-5684996 MAPK1/MAPK3 signaling 100/1591 255/10654 8.066304021069861e-22 2.4253909590625967e-20 1.35660567627084e-20 818/815/1839/2674/3562/4893/6464/6711/1437/3667/1844/5604/2065/3561/5525/5747/3815/5526/817/3674/1849/7010/1439/5594/2322/8074/409/3082/3568/10817/2064/5921/1438/2260/8452/5528/7316/9978/1950/3560/2263/4233/84078/3718/6714/5605/5715/6710/5519/2261/5159/3567/3558/3717/2247/2244/5698/3084/2335/2534/5529/1445/816/5702/2066/5894/3563/5979/1742/6233/5527/2885/6709/3716/2266/8660/7311/5518/5155/2243/1956/60/4254/3570/3845/3265/3559/369/801/7297/5781/3569/5696/5245/5156/7314/3572/5595/5515/5516 100 Hendra_virus R-HSA-392451 G beta:gamma signalling through PI3Kgamma 25/1591 25/10654 1.9224770025054696e-21 5.529211031118992e-20 3.092680395334886e-20 2788/5170/54331/59345/207/10681/51764/94235/55970/2792/146850/2793/23533/10000/5294/2785/2783/2784/2782/2786/208/387/2791/2790/2787 25 Hendra_virus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 25/1591 25/10654 1.9224770025054696e-21 5.529211031118992e-20 3.092680395334886e-20 1147/2308/5170/2309/842/572/207/4303/84335/1027/7249/6199/1026/55615/64223/2932/3164/10000/208/79109/2475/1385/2931/253260/4193 25 Hendra_virus R-HSA-168638 NOD1/2 Signaling Pathway 31/1591 36/10654 3.413997566692214e-21 9.610039959008083e-20 5.375230211387741e-20 1147/834/6885/842/10392/8767/330/23118/841/8517/7316/7335/64127/7128/1432/329/3656/5603/10454/83737/3654/7189/6233/7311/5600/7334/1540/3551/6300/7314/257397 31 Hendra_virus R-HSA-4420097 VEGFA-VEGFR2 Pathway 55/1591 99/10654 5.4280590812408945e-21 1.4961087842670216e-19 8.36825775024638e-20 5295/5170/5590/4893/857/5290/5335/558/5579/5291/1499/5747/4690/207/7422/5578/3315/57761/5921/9047/9261/55615/10768/6714/64223/1432/10000/3320/2534/4846/5603/998/208/1398/79109/7410/5580/2475/7409/3685/2185/3791/387/60/5296/117145/3845/5600/3265/6300/801/1536/5062/5879/253260 55 Hendra_virus R-HSA-5260271 Diseases of Immune System 24/1591 24/10654 1.3041436207168518e-20 3.45076402041679e-19 1.9301325586609407e-19 23643/1147/81793/4790/10333/7099/8517/4615/7098/7100/5970/4792/7096/929/114609/695/948/51135/81622/7187/7097/3551/4791/148022 24 Hendra_virus R-HSA-5602358 Diseases associated with the TLR signaling cascade 24/1591 24/10654 1.3041436207168518e-20 3.45076402041679e-19 1.9301325586609407e-19 23643/1147/81793/4790/10333/7099/8517/4615/7098/7100/5970/4792/7096/929/114609/695/948/51135/81622/7187/7097/3551/4791/148022 24 Hendra_virus R-HSA-446652 Interleukin-1 family signaling 67/1591 140/10654 1.601119933755993e-20 4.1534934752140763e-19 2.323193629371441e-19 8454/3557/1147/834/5777/8945/1326/351/4790/6885/90865/5604/11213/5783/10392/27178/8767/29110/3553/8878/54472/6500/23118/8517/4615/7316/3565/9978/6774/7335/5970/4792/59307/3606/177/8809/3146/5715/64127/3552/23291/4088/5698/3656/5771/10454/6288/5702/3654/7189/6285/6233/51135/7311/5599/7334/3551/7850/6416/5781/5696/4791/3554/7314/3596/257397/3556 67 Hendra_virus R-HSA-5673001 RAF/MAP kinase cascade 95/1591 249/10654 8.469727762496983e-20 2.1548941980352902e-18 1.20530741235534e-18 818/815/1839/2674/3562/4893/6464/6711/1437/3667/1844/5604/2065/3561/5525/5747/3815/5526/817/3674/1849/7010/1439/5594/2322/8074/409/3082/3568/10817/2064/5921/1438/2260/8452/5528/7316/9978/1950/3560/2263/4233/84078/3718/6714/5605/5715/6710/5519/2261/5159/3567/3558/3717/2247/2244/5698/3084/2335/2534/5529/1445/816/5702/2066/5894/3563/5979/1742/6233/5527/2885/6709/3716/2266/8660/7311/5518/5155/2243/1956/60/4254/3845/3265/3559/369/801/5696/5245/5156/7314/5595/5515/5516 95 Hendra_virus R-HSA-1227986 Signaling by ERBB2 36/1591 50/10654 1.4448154170296185e-19 3.606586408924878e-18 2.0172894501922975e-18 5295/1839/4893/8065/6464/5290/5335/2065/10273/207/5578/10193/9101/2064/7316/1950/5753/6714/10000/3320/3084/2534/2066/208/6233/2885/7525/5580/7311/387/1956/5581/3845/3265/11140/7314 36 Hendra_virus R-HSA-8939211 ESR-mediated signaling 88/1591 223/10654 1.5343629055710872e-19 3.759189118649164e-18 2.1026454631900084e-18 5295/2788/5170/3725/596/5590/1839/4893/6464/857/5290/54331/5241/4316/2309/5747/59345/5430/207/5451/2625/5594/1027/3315/10681/51764/94235/4318/200845/2100/4313/1950/865/55970/4314/6667/2792/2289/6714/2099/4609/8850/8503/10524/1387/5437/2793/10000/3320/2033/8243/2785/4846/9126/595/2783/4602/2784/2782/3065/2066/861/23028/2786/208/10498/3326/7514/1385/1025/2353/10499/1386/1956/5296/4343/3845/3276/3265/801/8202/8648/3480/2791/5595/2790/2787/6387 88 Hendra_virus R-HSA-1433557 Signaling by SCF-KIT 33/1591 43/10654 1.7356910300710674e-19 4.1751258777891315e-18 2.3352933859138e-18 5295/5777/4893/5290/3815/10019/5578/2241/4318/6776/9306/6774/6772/6714/8651/8503/867/4067/3717/2534/2885/7525/7006/7409/3932/4254/5296/3845/6777/3265/5781/5879/2242 33 Hendra_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 30/1591 37/10654 4.671935320925405e-19 1.1037447195686269e-17 6.1736288169371415e-18 1017/5170/1029/207/472/639/7316/890/80196/55615/64223/5519/1616/9099/10000/7157/8900/208/6233/5527/79109/2475/7311/5518/51230/7314/253260/4193/5515/5516 30 Hendra_virus R-HSA-389357 CD28 dependent PI3K/Akt signaling 22/1591 22/10654 5.991637158568625e-19 1.3906905194361914e-17 7.778616662001372e-18 5295/5170/1326/5290/207/941/57761/9020/55615/64223/8503/10000/2534/942/208/79109/2475/3932/5296/117145/940/253260 22 Hendra_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 28/1591 33/10654 6.774499837537754e-19 1.540557799909852e-17 8.616876583018069e-18 1147/351/4790/6885/10392/8767/23118/8517/7316/7335/5970/4792/177/3146/64127/3656/10454/6288/3654/7189/6285/6233/7311/7334/3551/4791/7314/257397 28 Hendra_virus R-HSA-194138 Signaling by VEGF 55/1591 107/10654 6.870212410784676e-19 1.540557799909852e-17 8.616876583018069e-18 5295/5170/5590/4893/857/5290/5335/558/5579/5291/1499/5747/4690/207/7422/5578/3315/57761/5921/9047/9261/55615/10768/6714/64223/1432/10000/3320/2534/4846/5603/998/208/1398/79109/7410/5580/2475/7409/3685/2185/3791/387/60/5296/117145/3845/5600/3265/6300/801/1536/5062/5879/253260 55 Hendra_virus R-HSA-6804757 Regulation of TP53 Degradation 29/1591 36/10654 2.5785001255218653e-18 5.685592776775714e-17 3.180150154810301e-17 1017/5170/1029/207/472/7316/890/80196/55615/64223/5519/1616/9099/10000/7157/8900/208/6233/5527/79109/2475/7311/5518/51230/7314/253260/4193/5515/5516 29 Hendra_virus R-HSA-912694 Regulation of IFNA signaling 24/1591 26/10654 3.1238142757094752e-18 6.775092273383009e-17 3.789545186926249e-17 3443/5777/3441/5770/3455/9021/11274/3449/3444/6772/8651/3451/3448/3440/3454/3439/3716/3452/3456/6773/7297/5781/3446/3445 24 Hendra_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 62/1591 134/10654 3.6909311000602786e-18 7.875970718354433e-17 4.4053048613622684e-17 5295/8454/1147/5170/3725/8945/5601/4893/6464/5290/5335/4790/6885/5291/7321/5336/5594/4214/6500/23118/8517/7316/7335/5970/4792/6850/10768/8915/7322/5715/4067/23291/5698/2534/10454/5702/695/7189/5609/6233/2885/7410/7006/7409/3702/2353/7311/5296/3845/5599/7334/3265/3551/801/6416/5062/5696/997/7314/5879/5595/257397 62 Hendra_virus R-HSA-9006931 Signaling by Nuclear Receptors 104/1591 299/10654 3.836275558877166e-18 8.056178673642048e-17 4.5061014501096866e-17 5295/2788/5170/3725/596/5590/1839/4893/6464/8841/857/5290/54331/5241/4316/2309/5747/59345/5160/5430/5165/207/5451/2625/64241/5594/1027/3315/10681/1737/51764/94235/4318/8050/200845/348/2100/4313/1950/865/55970/4314/6667/2792/2289/6714/2099/4609/8850/8503/55818/10524/1387/5437/2793/5467/10000/3320/2033/5162/8243/2785/4846/9126/595/2783/4602/2784/2782/3065/2066/861/23028/6256/2786/7376/208/10498/3326/7514/1385/1025/2353/1738/10499/1386/1956/5296/4343/3845/3276/3265/5164/801/29116/8202/8648/3480/2791/10062/5595/2790/2787/6387 104 Hendra_virus R-HSA-397795 G-protein beta:gamma signalling 27/1591 32/10654 3.908122823848976e-18 8.078822649925304e-17 4.518767015075378e-17 2788/5170/54331/59345/207/10681/51764/94235/55970/2792/146850/2793/23533/10000/5294/2785/2783/2784/2782/998/695/2786/208/387/2791/2790/2787 27 Hendra_virus R-HSA-389513 CTLA4 inhibitory signaling 21/1591 21/10654 4.057903051405095e-18 8.259393441552215e-17 4.6197665508304156e-17 5525/5526/207/941/5528/6714/5519/4067/10000/2534/5529/942/208/5527/7525/3932/5518/5781/1493/5515/5516 21 Hendra_virus R-HSA-912526 Interleukin receptor SHC signaling 24/1591 27/10654 2.4137088118716325e-17 4.838389027433591e-16 2.706279576946982e-16 5295/5777/3562/6464/5290/1437/5291/3561/1439/3568/1438/3560/3718/8503/3567/3558/3717/3636/3563/2885/3716/5293/5296/3559 24 Hendra_virus R-HSA-933541 TRAF6 mediated IRF7 activation 25/1591 29/10654 2.4787649184217653e-17 4.894635801599993e-16 2.7377403576598603e-16 3443/3665/3441/7186/29110/57506/3449/7706/3444/23586/1387/3451/3448/2033/64135/3440/3661/7189/3439/10010/3452/9641/3456/3446/3445 25 Hendra_virus R-HSA-166520 Signaling by NTRKs 51/1591 101/10654 3.4979656991010055e-17 6.80560091163328e-16 3.806609731374623e-16 5295/4908/627/1173/4893/6464/5290/3667/5335/4915/5291/5604/1849/5594/1785/10817/5528/6774/9261/6714/5605/26052/5519/1432/4909/4914/2534/4803/5603/2885/1398/8660/1385/163/1759/5518/387/5296/6197/3845/5600/3265/1399/6300/1020/5781/4916/5879/5595/5515/5516 51 Hendra_virus R-HSA-8848021 Signaling by PTK6 35/1591 54/10654 8.96518041497198e-17 1.6944190984297041e-15 9.477476438684665e-16 1017/1839/4893/5770/2065/207/9021/55620/27043/1027/898/3091/2064/5921/10657/7316/1950/5753/6774/867/6421/2908/3084/595/2066/6233/1398/7311/2034/387/1956/3845/3265/7314/5879 35 Hendra_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 35/1591 54/10654 8.96518041497198e-17 1.6944190984297041e-15 9.477476438684665e-16 1017/1839/4893/5770/2065/207/9021/55620/27043/1027/898/3091/2064/5921/10657/7316/1950/5753/6774/867/6421/2908/3084/595/2066/6233/1398/7311/2034/387/1956/3845/3265/7314/5879 35 Hendra_virus R-HSA-9020702 Interleukin-1 signaling 51/1591 103/10654 1.0187269234861295e-16 1.8982756616509144e-15 1.0617717230700504e-15 8454/3557/1147/8945/1326/351/4790/6885/5604/11213/10392/8767/3553/8878/54472/6500/23118/8517/4615/7316/9978/7335/5970/4792/177/3146/5715/64127/3552/23291/5698/3656/10454/6288/5702/3654/7189/6285/6233/51135/7311/7334/3551/7850/6416/5696/4791/3554/7314/257397/3556 51 Hendra_virus R-HSA-982772 Growth hormone receptor signaling 22/1591 24/10654 1.2198258960519687e-16 2.2414300839954927e-15 1.2537099487200791e-15 5777/3667/5770/2690/9021/5594/6776/6774/6772/8651/1442/4067/3717/5618/2688/8660/1154/5617/8835/6777/2689/5595 22 Hendra_virus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 21/1591 23/10654 7.576785569542515e-16 1.3731626450006504e-14 7.680577152686933e-15 5601/6885/10392/8767/23118/8517/7316/7335/64127/3656/10454/3654/7189/5609/6233/7311/5599/7334/6416/7314/257397 21 Hendra_virus R-HSA-8854691 Interleukin-20 family signaling 22/1591 25/10654 8.730965453816862e-16 1.5198772757104878e-14 8.501203205032208e-15 6775/50616/11009/53833/6776/6774/3718/6772/3717/29949/163702/58985/3716/282618/53832/50604/3588/6777/55801/6773/7297/5781 22 Hendra_virus R-HSA-9006335 Signaling by Erythropoietin 22/1591 25/10654 8.730965453816862e-16 1.5198772757104878e-14 8.501203205032208e-15 5295/4893/6464/5290/5335/5291/5336/6776/4067/23533/3717/5294/2057/2885/2056/7409/8660/5293/3845/6777/3265/1399 22 Hendra_virus R-HSA-937041 IKK complex recruitment mediated by RIP1 22/1591 25/10654 8.730965453816862e-16 1.5198772757104878e-14 8.501203205032208e-15 23643/1147/11035/7321/8737/330/7099/8517/7323/7316/7335/7322/329/929/7189/6233/7311/353376/7334/3551/7314/148022 22 Hendra_virus R-HSA-8964315 G beta:gamma signalling through BTK 18/1591 18/10654 1.2564832298074235e-15 2.1588666403054826e-14 1.2075293377370044e-14 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/695/2786/2791/2790/2787 18 Hendra_virus R-HSA-76002 Platelet activation, signaling and aggregation 90/1591 262/10654 1.8060863745333667e-15 3.0634003506508254e-14 1.7134665604547324e-14 5295/2788/928/5170/5777/5590/351/6464/5321/5290/54331/5579/5770/5291/5747/59345/51097/5336/2316/207/3674/813/7422/5578/5594/10681/409/3082/51764/94235/10447/1950/335/51706/55970/308/5216/6850/2792/6714/8503/4352/146850/1432/3920/27154/2793/4067/23533/2244/81/9948/2335/5294/2534/2785/2783/2784/1445/2782/998/5894/2786/2885/1398/7410/948/5580/2266/7409/3932/7076/3479/5155/2243/387/5296/5581/51368/7040/213/801/5781/2791/5879/5595/2790/2787/139322/7066 90 Hendra_virus R-HSA-1236394 Signaling by ERBB4 35/1591 58/10654 2.3244611461343383e-15 3.892736830804721e-14 2.177343352075203e-14 5295/1839/4893/6464/5290/2670/5241/2065/23118/51741/23385/348/6776/7316/1950/11059/4734/10413/6714/2099/1447/3084/2066/83737/3925/6285/1742/6233/2885/7311/1956/3845/3265/7314/6387 35 Hendra_virus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 24/1591 30/10654 3.10120875625072e-15 5.1286239806496285e-14 2.868618099531916e-14 11065/7319/7321/65264/7320/10477/92912/7326/7316/7317/54926/55236/3093/7322/7347/7328/7324/6233/7327/7311/55284/27338/997/7314 24 Hendra_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 19/1591 20/10654 3.194639125257431e-15 5.2179105712538034e-14 2.9185592008524675e-14 1147/11035/7321/8737/330/8517/7098/7323/7316/7335/7322/329/7189/6233/7311/7334/3551/7314/148022 19 Hendra_virus R-HSA-187037 Signaling by NTRK1 (TRKA) 42/1591 80/10654 3.656504256472452e-15 5.89945747721104e-14 3.299772133889773e-14 5295/1173/4893/6464/5290/3667/5335/4915/5291/5604/1849/5594/1785/5528/6774/9261/6714/5605/26052/5519/1432/4914/4803/5603/2885/1398/8660/1385/163/1759/5518/387/5296/6197/3845/5600/3265/1399/6300/5595/5515/5516 42 Hendra_virus R-HSA-912631 Regulation of signaling by CBL 20/1591 22/10654 4.6853834363343935e-15 7.468388296711328e-14 4.177329810707773e-14 5295/5290/5291/7316/3055/6850/8503/867/4067/2534/6233/2885/7525/1398/7409/7311/5293/5296/1399/7314 20 Hendra_virus R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 40/1591 75/10654 8.221634802949874e-15 1.294907481464605e-13 7.242868754979651e-14 5295/1839/5290/3667/5291/2065/3815/8074/3082/941/2064/2260/2100/1950/2263/4233/6714/2099/8503/2261/5159/2247/3084/2534/2066/942/2885/7409/8660/3932/5293/5155/1956/4254/118788/5296/5781/5156/940/5879 40 Hendra_virus R-HSA-186763 Downstream signal transduction 23/1591 29/10654 1.68416892458678e-14 2.621359396739188e-13 1.4662176519931967e-13 5295/4893/5290/5335/5291/4690/5921/6778/6776/6774/6772/6714/5159/2885/1398/5155/5296/3845/6777/3265/1399/5781/5156 23 Hendra_virus R-HSA-392851 Prostacyclin signalling through prostacyclin receptor 18/1591 19/10654 2.0528308653970976e-14 3.1580177150236744e-13 1.766389349295177e-13 2788/54331/59345/10681/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 18 Hendra_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 25/1591 34/10654 2.5523469623275437e-14 3.8813276220222307e-13 2.1709617840487154e-13 7321/29110/57506/9636/54476/7706/7323/7316/3093/23586/7322/7128/64135/83737/3661/9246/51191/6233/7311/7318/7187/5300/9641/1540/7314 25 Hendra_virus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 20/1591 23/10654 3.0870082632201936e-14 4.641036286636723e-13 2.5958933122533445e-13 11065/246184/7321/991/8697/8881/7316/891/51433/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 20 Hendra_virus R-HSA-5673000 RAF activation 24/1591 32/10654 4.050319562844927e-14 6.02086829398184e-13 3.367681434275557e-13 818/815/4893/5604/5525/5526/817/5528/6714/5605/5519/3717/5529/816/5894/5527/5518/3845/3265/369/801/5245/5515/5516 24 Hendra_virus R-HSA-390466 Chaperonin-mediated protein folding 45/1591 95/10654 5.222692207472019e-14 7.677357544983868e-13 4.2942135928103274e-13 2788/10694/26224/8841/54331/59345/10575/10681/5203/898/51764/1460/94235/10517/7203/10576/908/55970/6774/2792/26272/2793/26270/6950/7846/2785/55294/2783/26190/2784/2782/7157/2786/10574/6468/10383/60/54461/22948/26234/10693/2791/84261/2790/2787 45 Hendra_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 23/1591 30/10654 6.198898228318116e-14 9.01224434732403e-13 5.040862295555392e-13 7124/1147/7186/6885/8737/55072/330/23118/8517/7316/7128/7132/329/9099/10616/10454/6233/7311/8717/1540/3551/7314/257397 23 Hendra_virus R-HSA-8878166 Transcriptional regulation by RUNX2 52/1591 121/10654 8.026424412107621e-14 1.1542347279585198e-12 6.456037027130043e-13 8454/57154/7291/25/8841/23462/10273/207/5594/3280/6500/4086/5925/10013/7316/9978/891/865/4094/11059/9759/1026/10413/579/6772/6714/2099/5715/2932/6502/2908/5698/10000/2101/1749/595/55294/4488/5702/861/208/6233/7525/7311/367/860/1750/133522/5696/10891/7314/5595 52 Hendra_virus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 20/1591 24/10654 1.5918274415122516e-13 2.264502908731945e-12 1.2666153835688884e-12 6885/10392/8767/23118/8517/7316/7335/9261/64127/1432/3656/10454/3654/7189/6233/7311/5600/7334/7314/257397 20 Hendra_virus R-HSA-391251 Protein folding 46/1591 101/10654 1.6759761007709236e-13 2.3588472141701405e-12 1.3193854410324293e-12 2788/10694/26224/8841/54331/59345/10575/10681/5203/898/51764/1460/94235/10517/7203/10576/908/55970/6774/2792/26272/2793/26270/6950/7846/2785/55294/2783/26190/2784/2782/7157/2786/10574/6468/10383/60/54461/22948/26234/10693/2791/84261/6904/2790/2787 46 Hendra_virus R-HSA-8964616 G beta:gamma signalling through CDC42 18/1591 20/10654 1.765313344123933e-13 2.454993251936599e-12 1.373163270168619e-12 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/998/2786/2791/2790/2787 18 Hendra_virus R-HSA-5621481 C-type lectin receptors (CLRs) 57/1591 142/10654 1.7814009991376682e-13 2.454993251936599e-12 1.373163270168619e-12 8454/1147/5170/8945/4893/4790/6885/7321/5336/3553/9039/4582/6500/23118/841/8517/7316/64581/9020/7335/5970/4792/6850/10768/8915/6714/7322/5715/93978/1387/4067/23291/5698/2534/2033/10454/5702/9040/5894/7189/6233/5580/30835/7311/5971/3845/7334/3265/3551/801/5062/5696/997/26253/4791/7314/257397 57 Hendra_virus R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 27/1591 42/10654 4.152950773581126e-13 5.6642823437606484e-12 3.16823048706189e-12 2788/10694/54331/59345/10575/10681/51764/1460/94235/7203/10576/908/55970/2792/2793/6950/2785/2783/2784/2782/2786/10574/22948/10693/2791/2790/2787 27 Hendra_virus R-HSA-418592 ADP signalling through P2Y purinoceptor 1 20/1591 25/10654 6.840599899991965e-13 9.234809864989152e-12 5.165350944891891e-12 2788/5321/54331/59345/10681/51764/94235/55970/2792/6714/1432/2793/2785/2783/2784/2782/2786/2791/2790/2787 20 Hendra_virus R-HSA-75893 TNF signaling 27/1591 43/10654 9.580409126126633e-13 1.2802910377641955e-11 7.161113892256271e-12 7124/1147/25999/7186/6885/8737/55072/330/23118/841/8517/7316/7128/7132/329/9099/10616/10454/8567/6233/7311/8772/8717/1540/3551/7314/257397 27 Hendra_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 17/1591 19/10654 1.0745894134448334e-12 1.3938056803799162e-11 7.796040842638988e-12 5295/4893/6464/5290/5335/7316/1950/867/3320/6233/2885/7311/1956/3845/3265/11140/7314 17 Hendra_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 17/1591 19/10654 1.0745894134448334e-12 1.3938056803799162e-11 7.796040842638988e-12 5295/4893/6464/5290/5335/7316/1950/867/3320/6233/2885/7311/1956/3845/3265/11140/7314 17 Hendra_virus R-HSA-5686938 Regulation of TLR by endogenous ligand 17/1591 19/10654 1.0745894134448334e-12 1.3938056803799162e-11 7.796040842638988e-12 23643/653509/6271/6280/10333/7099/338/7096/6279/3146/2244/929/948/2266/2243/7097/3929 17 Hendra_virus R-HSA-9614085 FOXO-mediated transcription 34/1591 65/10654 1.7972053667435146e-12 2.308449223496767e-11 1.2911960887283504e-11 2308/857/2309/65018/10018/356/7532/207/10971/4303/1027/7295/4287/114907/5443/1026/84676/8850/1647/1387/4088/2908/10000/2033/3630/3066/3065/4087/56729/208/604/23411/25942/10891 34 Hendra_virus R-HSA-69231 Cyclin D associated events in G1 27/1591 44/10654 2.1285217542285264e-12 2.6819374103279433e-11 1.5001010458372473e-11 8454/25/894/902/1029/7027/1027/6500/5925/7316/1869/5753/1026/6714/1031/5519/4067/3717/6502/595/896/6233/7311/5518/7314/5515/5516 27 Hendra_virus R-HSA-69236 G1 Phase 27/1591 44/10654 2.1285217542285264e-12 2.6819374103279433e-11 1.5001010458372473e-11 8454/25/894/902/1029/7027/1027/6500/5925/7316/1869/5753/1026/6714/1031/5519/4067/3717/6502/595/896/6233/7311/5518/7314/5515/5516 27 Hendra_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 28/1591 47/10654 2.33892037757694e-12 2.919237414654992e-11 1.6328312069876753e-11 8454/8841/892/23462/55534/3280/6500/84441/3091/10013/10046/7316/9978/9759/4609/10014/8850/1387/2033/55294/3066/3065/9794/6233/7311/388585/3516/7314 28 Hendra_virus R-HSA-198323 AKT phosphorylates targets in the cytosol 14/1591 14/10654 2.612191944943807e-12 3.229841068374446e-11 1.8065626535125395e-11 1147/842/572/207/84335/1027/7249/1026/2932/10000/208/2931/23608/4193 14 Hendra_virus R-HSA-933542 TRAF6 mediated NF-kB activation 19/1591 24/10654 3.708448089802604e-12 4.54284891000819e-11 2.5409736911610436e-11 1147/351/7186/4790/57506/4214/7706/8517/5970/4792/177/3146/23586/64135/6288/7189/6285/3551/4791 19 Hendra_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 44/1591 101/10654 3.764527414000502e-12 4.569238319929049e-11 2.5557342076700652e-11 8454/1147/5170/8945/4790/6885/7321/5336/3553/9039/6500/23118/841/8517/7316/64581/9020/7335/5970/4792/6850/10768/8915/6714/7322/5715/23291/5698/10454/5702/9040/7189/6233/5580/7311/5971/7334/3551/801/5696/997/4791/7314/257397 44 Hendra_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 15/1591 16/10654 5.334342673986603e-12 6.357959781697546e-11 3.5562284493244023e-11 8454/1147/8945/1326/4790/5604/6500/8517/7316/23291/6233/7311/3551/6416/7314 15 Hendra_virus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 15/1591 16/10654 5.334342673986603e-12 6.357959781697546e-11 3.5562284493244023e-11 23643/6885/23118/7099/7316/929/3656/10454/7189/6233/7311/353376/7314/148022/257397 15 Hendra_virus R-HSA-418217 G beta:gamma signalling through PLC beta 17/1591 20/10654 6.16358519462866e-12 7.280735011155104e-11 4.0723687893082226e-11 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Hendra_virus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 16/1591 18/10654 6.500300704962624e-12 7.61052905545624e-11 4.256834089975524e-11 23643/3665/29110/7099/7316/929/3661/6233/10010/7311/7187/9641/353376/5781/7314/148022 16 Hendra_virus R-HSA-2871796 FCERI mediated MAPK activation 22/1591 32/10654 8.454205672583706e-12 9.811328162130037e-11 5.487817717291178e-11 3725/5601/4893/6464/5335/5336/5594/4214/6850/4067/5609/2885/7410/7409/2353/3845/5599/3265/6416/5062/5879/5595 22 Hendra_virus R-HSA-2262752 Cellular responses to stress 127/1591 479/10654 1.2128996460881679e-11 1.3953619406736053e-10 7.804745548741255e-11 1017/818/6118/3725/815/5601/11065/4790/5241/9448/246184/112399/1029/7027/1915/526/7321/2146/817/6045/7422/8697/5594/3308/84335/1027/898/7295/10294/5925/3091/1051/10013/545/472/3576/3313/8881/7323/7316/9978/1869/890/10935/6774/5970/1026/1639/9261/832/6667/2289/7415/51433/64223/1031/7322/5715/3552/1432/2932/10524/1387/7846/3310/529/2908/5698/3320/2033/23512/6009/6767/3301/816/25994/7428/5702/7157/8453/8900/51529/50507/23135/7324/64682/29945/10393/22824/5609/6233/2056/51434/3326/2475/2353/51343/7311/367/2034/57634/10383/23411/4343/6117/6197/29882/5599/648/5600/54583/3312/4217/528/3456/2113/6416/1536/3569/3297/57521/5696/768/7314/996/5595/4193 127 Hendra_virus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 19/1591 25/10654 1.3285677072513356e-11 1.5152543764599284e-10 8.475345718672313e-11 11065/246184/7321/991/8697/8881/7316/51433/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 19 Hendra_virus R-HSA-5357801 Programmed Cell Death 63/1591 181/10654 1.712929726006235e-11 1.9369282286378198e-10 1.0833914506364223e-10 23643/2934/11035/596/7186/2339/1499/4976/10018/5747/1029/7027/842/572/8737/356/7532/207/10971/5594/10059/355/330/7533/841/7099/7316/1869/6774/5339/4836/660/115209/3146/5715/329/999/598/836/929/5698/10000/5702/7157/3836/208/6233/5580/6709/7311/840/8772/5599/353376/8717/7431/26060/8743/5062/5696/7314/5595/148022 63 Hendra_virus R-HSA-5357905 Regulation of TNFR1 signaling 22/1591 33/10654 2.1791125385199807e-11 2.443191430899944e-10 1.3665621004277844e-10 7124/1147/25999/7186/8737/55072/330/841/8517/7316/7128/7132/329/9099/10616/8567/6233/7311/8717/1540/3551/7314 22 Hendra_virus R-HSA-2559583 Cellular Senescence 66/1591 195/10654 2.3421844039856473e-11 2.603957955019337e-10 1.4564844192851927e-10 1017/3725/5601/11065/4790/9448/246184/1029/7027/7321/2146/6045/8697/5594/1027/898/7295/5925/1051/472/3576/8881/7316/1869/890/6774/5970/1026/9261/6667/51433/1031/3552/1432/10524/23512/7157/8900/51529/23135/7324/64682/29945/10393/5609/6233/51434/2353/51343/7311/57634/4343/6197/29882/5599/648/5600/4217/3456/2113/6416/3569/7314/996/5595/4193 66 Hendra_virus R-HSA-3700989 Transcriptional Regulation by TP53 103/1591 365/10654 2.3876888219021008e-11 2.632426926147066e-10 1.4724081068396289e-10 9377/1017/23774/834/6118/2176/5170/3725/4436/902/64769/7862/1029/7027/5430/7532/207/10971/1027/58484/7249/898/355/7295/7533/1460/4292/545/472/332/639/7316/1869/891/890/80196/84289/1026/55615/6790/6341/5111/8148/64223/9150/5519/1647/1432/10524/1387/27154/5437/1616/9099/51499/10000/51755/2033/10128/5728/6009/7994/3066/3065/7157/55215/8900/5371/208/10498/6233/5527/79109/2968/2475/672/1025/2353/604/7311/51204/5518/6834/1386/5300/4343/6117/1340/1327/5600/4697/3276/5564/51230/1020/2744/57521/7248/7314/253260/4193/5515/5516 103 Hendra_virus R-HSA-500657 Presynaptic function of Kainate receptors 17/1591 21/10654 2.784230523296097e-11 3.044245439934493e-10 1.7027525514372823e-10 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Hendra_virus R-HSA-418346 Platelet homeostasis 39/1591 88/10654 3.331049200531689e-11 3.60224955768963e-10 2.014863698178629e-10 2788/5777/5321/54331/5525/59345/6717/5526/2268/10681/51764/94235/338/488/5528/55970/2778/2792/5519/1432/2793/4843/2785/4846/2783/2784/5529/2782/2786/5527/5518/801/5781/4842/2791/2790/5515/2787/5516 39 Hendra_virus R-HSA-1170546 Prolactin receptor signaling 14/1591 15/10654 3.3762580888398645e-11 3.60224955768963e-10 2.014863698178629e-10 8454/8945/2690/6500/6776/9978/1442/3717/5618/2688/5617/6777/2689/5781 14 Hendra_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 14/1591 15/10654 3.3762580888398645e-11 3.60224955768963e-10 2.014863698178629e-10 54106/3665/4615/7316/7335/3654/7189/6233/51311/51135/7311/7334/51284/7314 14 Hendra_virus R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 16/1591 19/10654 3.543742759305757e-11 3.750697336449213e-10 2.097895713509008e-10 11065/246184/7321/991/8697/8881/51433/51529/7324/64682/29945/10393/51434/51343/29882/996 16 Hendra_virus R-HSA-432142 Platelet sensitization by LDL 15/1591 17/10654 3.9048448080362043e-11 4.0678028984503135e-10 2.2752639038951114e-10 5777/5321/5525/5526/2268/338/5528/5519/1432/5529/5527/5518/5781/5515/5516 15 Hendra_virus R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 15/1591 17/10654 3.9048448080362043e-11 4.0678028984503135e-10 2.2752639038951114e-10 23643/6885/23118/7099/7316/929/3656/10454/7189/6233/7311/353376/7314/148022/257397 15 Hendra_virus R-HSA-202403 TCR signaling 47/1591 119/10654 4.663250616747653e-11 4.819906692154019e-10 2.6959417628072367e-10 5295/8454/1147/5170/8945/5290/5335/4790/6885/5291/4690/7321/8767/6500/3123/23118/5788/8517/919/7316/3122/7335/5970/4792/8915/3113/7322/5715/23291/5698/5728/1445/5702/7189/6233/3702/26191/7311/3932/5296/3127/7334/3551/5062/5696/997/7314 47 Hendra_virus R-HSA-5218920 VEGFR2 mediated vascular permeability 20/1591 29/10654 7.039450210230443e-11 7.16399432933452e-10 4.007071658131176e-10 5170/857/1499/207/57761/55615/64223/10000/3320/4846/208/79109/7410/2475/7409/117145/801/5062/5879/253260 20 Hendra_virus R-HSA-8863795 Downregulation of ERBB2 signaling 20/1591 29/10654 7.039450210230443e-11 7.16399432933452e-10 4.007071658131176e-10 1839/8065/2065/10273/207/10193/9101/2064/7316/1950/10000/3320/3084/2066/208/6233/7311/1956/11140/7314 20 Hendra_virus R-HSA-5654741 Signaling by FGFR3 24/1591 40/10654 7.161265698466717e-11 7.17754130232687e-10 4.014648952170736e-10 5295/4893/6464/5290/5335/5594/8074/10817/7316/6714/2261/867/2247/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 24 Hendra_virus R-HSA-5675221 Negative regulation of MAPK pathway 24/1591 40/10654 7.161265698466717e-11 7.17754130232687e-10 4.014648952170736e-10 4893/1844/5604/5525/5526/1849/5594/5528/7316/5605/5519/5529/5894/6233/5527/7311/5518/3845/3265/369/7314/5595/5515/5516 24 Hendra_virus R-HSA-109581 Apoptosis 61/1591 178/10654 7.51702568113123e-11 7.477462388072645e-10 4.1824052661933163e-10 23643/2934/596/7186/2339/1499/4976/10018/5747/1029/7027/842/572/8737/356/7532/207/10971/5594/10059/355/7533/841/7099/7316/1869/6774/5339/4836/660/115209/3146/5715/329/999/598/836/929/5698/10000/5702/7157/3836/208/6233/5580/6709/7311/840/8772/5599/353376/8717/7431/26060/8743/5062/5696/7314/5595/148022 61 Hendra_virus R-HSA-8953897 Cellular responses to external stimuli 127/1591 493/10654 9.849631532180974e-11 9.671280688630242e-10 5.409484285401646e-10 1017/818/6118/3725/815/5601/11065/4790/5241/9448/246184/112399/1029/7027/1915/526/7321/2146/817/6045/7422/8697/5594/3308/84335/1027/898/7295/10294/5925/3091/1051/10013/545/472/3576/3313/8881/7323/7316/9978/1869/890/10935/6774/5970/1026/1639/9261/832/6667/2289/7415/51433/64223/1031/7322/5715/3552/1432/2932/10524/1387/7846/3310/529/2908/5698/3320/2033/23512/6009/6767/3301/816/25994/7428/5702/7157/8453/8900/51529/50507/23135/7324/64682/29945/10393/22824/5609/6233/2056/51434/3326/2475/2353/51343/7311/367/2034/57634/10383/23411/4343/6117/6197/29882/5599/648/5600/54583/3312/4217/528/3456/2113/6416/1536/3569/3297/57521/5696/768/7314/996/5595/4193 127 Hendra_virus R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 21/1591 32/10654 9.868653763908409e-11 9.671280688630242e-10 5.409484285401646e-10 2788/54331/59345/5594/10681/409/51764/94235/55970/2792/6714/2793/2785/2783/2784/2782/2786/2791/5595/2790/2787 21 Hendra_virus R-HSA-392170 ADP signalling through P2Y purinoceptor 12 17/1591 22/10654 1.0541473110284423e-10 1.0254683033019332e-9 5.735801545301818e-10 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Hendra_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 12/1591 12/10654 1.1871938954865342e-10 1.1381576258903514e-9 6.366112193188661e-10 3665/29110/7098/7316/3661/6233/10010/7311/7187/9641/7314/148022 12 Hendra_virus R-HSA-9020558 Interleukin-2 signaling 12/1591 12/10654 1.1871938954865342e-10 1.1381576258903514e-9 6.366112193188661e-10 6464/3561/6776/3560/6850/3718/3558/3716/3932/2185/6777/3559 12 Hendra_virus R-HSA-114604 GPVI-mediated activation cascade 22/1591 35/10654 1.2272424974381749e-10 1.1680876432451117e-9 6.533521209383089e-10 5295/5170/5777/5590/5290/5291/5336/6850/8503/146850/4067/23533/5294/2534/998/7410/7409/3932/387/5296/5781/5879 22 Hendra_virus R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 15/1591 18/10654 2.017891849573594e-10 1.9069077978470463e-9 1.0665999776317568e-9 5295/8805/11052/26127/5290/613/9208/6776/6774/6772/399687/2885/6777/7750/1523 15 Hendra_virus R-HSA-1643713 Signaling by EGFR in Cancer 18/1591 25/10654 2.1022728749938535e-10 1.9586669109977944e-9 1.0955506531658109e-9 5295/1839/4893/6464/5290/5335/7316/1950/867/3320/6233/2885/7311/1956/3845/3265/11140/7314 18 Hendra_virus R-HSA-9006115 Signaling by NTRK2 (TRKB) 18/1591 25/10654 2.1022728749938535e-10 1.9586669109977944e-9 1.0955506531658109e-9 5295/4908/627/4893/6464/5290/5335/4915/10817/6714/4909/2534/2885/3845/3265/1020/5781/5879 18 Hendra_virus R-HSA-877312 Regulation of IFNG signaling 13/1591 14/10654 2.1265030243820016e-10 1.9673870638163552e-9 1.1004281384913854e-9 3460/5777/5770/9021/6772/8651/3459/3717/5771/3458/3716/5781/8554 13 Hendra_virus R-HSA-74751 Insulin receptor signalling cascade 28/1591 54/10654 2.1624043911799186e-10 1.9867090343965502e-9 1.1112355899119026e-9 5295/54106/5170/3643/4893/6464/5290/3667/5291/5594/2322/8074/57761/2260/5140/2263/2261/2247/3630/208/2885/8660/5296/117145/3845/3265/5781/5595 28 Hendra_virus R-HSA-1433559 Regulation of KIT signaling 14/1591 16/10654 2.3276024838928225e-10 2.1091904699932904e-9 1.1797437247128005e-9 5777/3815/10019/5578/9306/6714/8651/867/4067/2534/2885/7525/3932/4254 14 Hendra_virus R-HSA-193639 p75NTR signals via NF-kB 14/1591 16/10654 2.3276024838928225e-10 2.1091904699932904e-9 1.1797437247128005e-9 4790/8767/8878/4615/7316/5970/4792/4803/3654/7189/6233/7311/3551/7314 14 Hendra_virus R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 23/1591 39/10654 2.923754521637573e-10 2.6313790694738158e-9 1.4718220040896626e-9 10694/26224/8841/10575/898/10517/7203/10576/908/6774/26272/26270/6950/55294/26190/7157/10574/6468/54461/22948/26234/10693/84261 23 Hendra_virus R-HSA-73887 Death Receptor Signalling 51/1591 141/10654 3.0669511130390576e-10 2.7416056233450497e-9 1.533475556519529e-9 7124/1147/25999/8841/7186/4790/6885/10018/572/8737/8767/55072/356/8878/355/330/23118/23385/841/8517/4615/7316/5970/4792/7128/7132/329/9099/836/10616/4803/10454/3066/3065/8567/3654/7189/6233/7410/7409/7311/387/8772/5599/8717/1540/3551/8743/7314/5879/257397 51 Hendra_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 29/1591 58/10654 3.2101216469369e-10 2.7758110711748485e-9 1.5526078553812458e-9 8454/8841/142678/892/23462/55534/3280/6500/84441/10013/23385/10046/7316/9978/9759/4609/10014/8850/1387/2033/55294/3066/3065/9794/6233/7311/388585/3516/7314 29 Hendra_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 29/1591 58/10654 3.2101216469369e-10 2.7758110711748485e-9 1.5526078553812458e-9 8454/8841/142678/892/23462/55534/3280/6500/84441/10013/23385/10046/7316/9978/9759/4609/10014/8850/1387/2033/55294/3066/3065/9794/6233/7311/388585/3516/7314 29 Hendra_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 29/1591 58/10654 3.2101216469369e-10 2.7758110711748485e-9 1.5526078553812458e-9 8454/8841/142678/892/23462/55534/3280/6500/84441/10013/23385/10046/7316/9978/9759/4609/10014/8850/1387/2033/55294/3066/3065/9794/6233/7311/388585/3516/7314 29 Hendra_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 29/1591 58/10654 3.2101216469369e-10 2.7758110711748485e-9 1.5526078553812458e-9 8454/8841/142678/892/23462/55534/3280/6500/84441/10013/23385/10046/7316/9978/9759/4609/10014/8850/1387/2033/55294/3066/3065/9794/6233/7311/388585/3516/7314 29 Hendra_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 29/1591 58/10654 3.2101216469369e-10 2.7758110711748485e-9 1.5526078553812458e-9 8454/8841/142678/892/23462/55534/3280/6500/84441/10013/23385/10046/7316/9978/9759/4609/10014/8850/1387/2033/55294/3066/3065/9794/6233/7311/388585/3516/7314 29 Hendra_virus R-HSA-202040 G-protein activation 19/1591 28/10654 3.294639307539408e-10 2.8303946778406735e-9 1.5831383685578974e-9 2788/54331/59345/10681/51764/94235/55970/5443/2792/4988/2793/2785/2783/2784/2782/2786/2791/2790/2787 19 Hendra_virus R-HSA-8852135 Protein ubiquitination 35/1591 79/10654 3.435416930250266e-10 2.9322945798200656e-9 1.6401345344420624e-9 11065/7319/7321/65264/9646/7320/10477/92912/7336/7326/5591/7323/7316/7317/54926/55236/8915/5111/7415/3093/7322/7347/118424/7328/7324/6233/7327/23168/7311/55284/27338/7334/3105/997/7314 35 Hendra_virus R-HSA-428930 Thromboxane signalling through TP receptor 17/1591 23/10654 3.4773857637571193e-10 2.9490906188786335e-9 1.649529144346326e-9 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Hendra_virus R-HSA-202424 Downstream TCR signaling 40/1591 98/10654 4.0145947625324937e-10 3.382999280783751e-9 1.8922293785185004e-9 5295/8454/1147/5170/8945/5290/4790/6885/5291/7321/8767/6500/3123/23118/8517/919/7316/3122/7335/5970/4792/8915/3113/7322/5715/23291/5698/5728/5702/7189/6233/7311/3932/5296/3127/7334/3551/5696/997/7314 40 Hendra_virus R-HSA-5688426 Deubiquitination 85/1591 297/10654 6.529416558113656e-10 5.4673532318888395e-9 3.0580811727874087e-9 8295/23326/7186/6885/90865/7321/991/8737/10392/8767/171023/4738/2625/9817/57506/4303/91833/57646/409/6478/4086/1080/330/3091/9101/11274/4287/7706/8517/64750/7416/29086/7316/890/7417/4792/8678/2099/4609/7415/23586/5715/64127/8850/7128/3416/329/6502/7347/9099/4088/5698/9146/2033/64135/5728/10454/8473/5702/7157/8900/9929/8975/4087/63891/7189/57599/6233/672/7048/9804/7311/367/114548/7187/387/60/7040/5887/7345/1540/154/5696/7314/4193 85 Hendra_virus R-HSA-2428924 IGF1R signaling cascade 27/1591 53/10654 7.649227362486407e-10 6.3647344657669905e-9 3.560017766188642e-9 5295/54106/5170/4893/6464/5290/3667/5291/2322/8074/57761/2260/5140/2263/2261/2247/8471/208/2885/8660/3479/5296/117145/3845/3265/5781/3480 27 Hendra_virus R-HSA-8878159 Transcriptional regulation by RUNX3 39/1591 96/10654 7.831768400288967e-10 6.47589349598894e-9 3.6221928851336474e-9 57154/51176/2309/1499/10018/1029/55534/3280/84441/463/6097/10046/64750/7316/865/9759/1026/10413/6714/4609/5715/8850/1387/4088/5698/2033/595/5702/7157/861/9794/6233/7311/7040/3845/3516/5696/7314/4193 39 Hendra_virus R-HSA-1059683 Interleukin-6 signaling 11/1591 11/10654 7.997028246622274e-10 6.490839490970104e-9 3.6305527009205413e-9 9021/6774/6772/867/3717/3716/3570/7297/5781/3569/3572 11 Hendra_virus R-HSA-5603041 IRAK4 deficiency (TLR2/4) 11/1591 11/10654 7.997028246622274e-10 6.490839490970104e-9 3.6305527009205413e-9 23643/10333/7099/4615/7096/929/114609/695/948/51135/7097 11 Hendra_virus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 11/1591 11/10654 7.997028246622274e-10 6.490839490970104e-9 3.6305527009205413e-9 6885/23118/7098/7316/10454/7189/6233/7311/7314/148022/257397 11 Hendra_virus R-HSA-176412 Phosphorylation of the APC/C 15/1591 19/10654 8.2560827507349435e-010 6.660242365379469e-9 3.725305631429182e-9 11065/246184/7321/8697/8881/891/51433/51529/7324/64682/29945/10393/51434/29882/996 15 Hendra_virus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 25/1591 47/10654 9.964475641368776e-10 7.847024567577912e-9 4.389114270602913e-9 818/815/4893/5604/817/3674/5594/409/6714/5605/3717/2244/2335/1445/816/5894/2266/2243/60/3845/3265/369/801/5245/5595 25 Hendra_virus R-HSA-6802949 Signaling by RAS mutants 25/1591 47/10654 9.964475641368776e-10 7.847024567577912e-9 4.389114270602913e-9 818/815/4893/5604/817/3674/5594/409/6714/5605/3717/2244/2335/1445/816/5894/2266/2243/60/3845/3265/369/801/5245/5595 25 Hendra_virus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 25/1591 47/10654 9.964475641368776e-10 7.847024567577912e-9 4.389114270602913e-9 818/815/4893/5604/817/3674/5594/409/6714/5605/3717/2244/2335/1445/816/5894/2266/2243/60/3845/3265/369/801/5245/5595 25 Hendra_virus R-HSA-9649948 Signaling downstream of RAS mutants 25/1591 47/10654 9.964475641368776e-10 7.847024567577912e-9 4.389114270602913e-9 818/815/4893/5604/817/3674/5594/409/6714/5605/3717/2244/2335/1445/816/5894/2266/2243/60/3845/3265/369/801/5245/5595 25 Hendra_virus R-HSA-392518 Signal amplification 20/1591 32/10654 1.0085340046545714e-9 7.89520998910058e-9 4.416066055883923e-9 2788/5321/54331/59345/10681/51764/94235/55970/2792/6714/1432/2793/2785/2783/2784/2782/2786/2791/2790/2787 20 Hendra_virus R-HSA-6783589 Interleukin-6 family signaling 17/1591 24/10654 1.026061036736065e-9 7.985169127069493e-9 4.466383336380518e-9 3589/9021/3976/6774/6772/867/3717/3716/1270/3570/5008/3977/7297/5781/3569/1489/3572 17 Hendra_virus R-HSA-5654743 Signaling by FGFR4 23/1591 41/10654 1.156733174637721e-9 8.949461930091841e-9 5.005745901941014e-9 5295/4893/6464/5290/5335/5594/8074/10817/7316/6714/867/2247/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 23 Hendra_virus R-HSA-5655302 Signaling by FGFR1 in disease 22/1591 38/10654 1.1731934258690306e-9 8.971878048697847e-9 5.0182840181681075e-9 5295/8805/4893/11052/26127/5290/5335/613/8074/2260/9208/6776/6774/6772/399687/2247/2885/3845/6777/3265/7750/1523 22 Hendra_virus R-HSA-5689896 Ovarian tumor domain proteases 22/1591 38/10654 1.1731934258690306e-9 8.971878048697847e-9 5.0182840181681075e-9 7321/8737/10392/8767/57506/7706/8517/7316/2099/7415/23586/64127/7128/64135/5728/7157/7189/6233/7311/7187/387/7314 22 Hendra_virus R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 27/1591 54/10654 1.3136050333792877e-9 9.987927926211481e-9 5.586596118969385e-9 5295/54106/5170/4893/6464/5290/3667/5291/2322/8074/57761/2260/5140/2263/2261/2247/8471/208/2885/8660/3479/5296/117145/3845/3265/5781/3480 27 Hendra_virus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 12/1591 13/10654 1.3319730946560932e-9 1.0012502296761428e-8 5.600341420713119e-9 2065/207/10193/9101/2064/7316/10000/3084/208/6233/7311/7314 12 Hendra_virus R-HSA-209560 NF-kB is activated and signals survival 12/1591 13/10654 1.3319730946560932e-9 1.0012502296761428e-8 5.600341420713119e-9 4790/8878/7316/5970/4792/4803/3654/7189/6233/7311/3551/7314 12 Hendra_virus R-HSA-5637810 Constitutive Signaling by EGFRvIII 13/1591 15/10654 1.3754204925119206e-9 1.0222928716816129e-8 5.718040249768659e-9 5295/4893/6464/5290/5335/1950/867/3320/2885/1956/3845/3265/11140 13 Hendra_virus R-HSA-5637812 Signaling by EGFRvIII in Cancer 13/1591 15/10654 1.3754204925119206e-9 1.0222928716816129e-8 5.718040249768659e-9 5295/4893/6464/5290/5335/1950/867/3320/2885/1956/3845/3265/11140 13 Hendra_virus R-HSA-2424491 DAP12 signaling 19/1591 30/10654 1.927399290076233e-9 1.424552659648523e-8 7.968019411488338e-9 5295/4893/6464/5290/5335/5291/5336/54209/6850/2534/695/2885/7410/3133/3932/5296/3845/3265/5879 19 Hendra_virus R-HSA-1266695 Interleukin-7 signaling 21/1591 36/10654 2.3246619507805515e-9 1.7086265338237054e-8 9.556943575431157e-9 5295/54014/3667/6597/64109/3561/3082/6776/6774/3718/8651/8503/3716/85480/8660/1154/3575/5296/8835/6777/3574 21 Hendra_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 34/1591 80/10654 2.3416286881625817e-9 1.7115882621210474e-8 9.573509553813869e-9 201626/5335/2316/4600/9636/11274/8638/25820/7706/7316/4734/3434/6772/23586/6041/4939/6059/3661/7324/3836/9246/51191/4599/6233/3716/7311/7318/5610/5300/4940/7334/4938/7314/5595 34 Hendra_virus R-HSA-2428928 IRS-related events triggered by IGF1R 26/1591 52/10654 2.658318213502392e-9 1.932392855199816e-8 1.0808546582372365e-8 5295/54106/5170/4893/5290/3667/5291/2322/8074/57761/2260/5140/2263/2261/2247/8471/208/2885/8660/3479/5296/117145/3845/3265/5781/3480 26 Hendra_virus R-HSA-1980143 Signaling by NOTCH1 32/1591 73/10654 2.715801059557485e-9 1.963390602073526e-8 1.0981927781817153e-8 8454/8841/142678/892/23462/55534/3280/6500/409/84441/3091/10013/23385/10046/7316/9978/9759/4609/10014/8850/1387/2033/55294/3066/3065/83737/9794/6233/7311/388585/3516/7314 32 Hendra_virus R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 15/1591 20/10654 2.844834708733652e-9 2.0126825238794767e-8 1.1257634676272205e-8 11065/246184/7321/991/8697/8881/51433/51529/7324/64682/29945/10393/51434/29882/996 15 Hendra_virus R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 15/1591 20/10654 2.844834708733652e-9 2.0126825238794767e-8 1.1257634676272205e-8 11065/246184/7321/991/8697/8881/51433/51529/7324/64682/29945/10393/51434/29882/996 15 Hendra_virus R-HSA-5213460 RIPK1-mediated regulated necrosis 15/1591 20/10654 2.844834708733652e-9 2.0126825238794767e-8 1.1257634676272205e-8 11035/7186/8737/356/355/330/841/7316/329/6233/7311/8772/8717/8743/7314 15 Hendra_virus R-HSA-5218859 Regulated Necrosis 15/1591 20/10654 2.844834708733652e-9 2.0126825238794767e-8 1.1257634676272205e-8 11035/7186/8737/356/355/330/841/7316/329/6233/7311/8772/8717/8743/7314 15 Hendra_virus R-HSA-210993 Tie2 Signaling 14/1591 18/10654 4.409106776888347e-9 3.086374743821843e-8 1.7263169390991412e-8 5295/4893/6464/5290/5291/7010/2888/2885/285/5296/3845/3265/5781/9046 14 Hendra_virus R-HSA-5675482 Regulation of necroptotic cell death 14/1591 18/10654 4.409106776888347e-9 3.086374743821843e-8 1.7263169390991412e-8 7186/8737/356/355/330/841/7316/329/6233/7311/8772/8717/8743/7314 14 Hendra_virus R-HSA-5633007 Regulation of TP53 Activity 53/1591 160/10654 5.175411643756206e-9 3.6037208445734e-8 2.015686640199786e-8 1017/23774/6118/5170/64769/7862/1029/207/1460/545/472/639/7316/890/80196/84289/55615/6790/8148/64223/5519/1432/10524/27154/1616/9099/10000/2033/7994/3066/3065/7157/8900/5371/208/6233/5527/79109/2475/672/7311/5518/5300/6117/5600/5564/51230/1020/7314/253260/4193/5515/5516 53 Hendra_virus R-HSA-390450 Folding of actin by CCT/TriC 10/1591 10/10654 5.3839575368151324e-9 3.6716370212404227e-8 2.053674524352164e-8 10694/10575/7203/10576/908/6950/10574/60/22948/10693 10 Hendra_virus R-HSA-5602498 MyD88 deficiency (TLR2/4) 10/1591 10/10654 5.3839575368151324e-9 3.6716370212404227e-8 2.053674524352164e-8 23643/10333/7099/4615/7096/929/114609/695/948/7097 10 Hendra_virus R-HSA-9020958 Interleukin-21 signaling 10/1591 10/10654 5.3839575368151324e-9 3.6716370212404227e-8 2.053674524352164e-8 3561/6775/6776/50615/6774/3718/6772/3716/6777/59067 10 Hendra_virus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 10/1591 10/10654 5.3839575368151324e-9 3.6716370212404227e-8 2.053674524352164e-8 6885/23118/7316/3656/10454/7189/6233/7311/7314/257397 10 Hendra_virus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 35/1591 86/10654 5.4578951126617955e-9 3.7029719148982337e-8 2.0712012222408866e-8 5295/25/5290/5335/5291/5747/4690/5336/4771/5594/2268/4644/919/3055/6850/10768/6714/4067/3320/2534/998/695/2885/7525/1398/7410/10096/3326/5580/7409/60/5296/5581/5879/5595 35 Hendra_virus R-HSA-1295596 Spry regulation of FGF signaling 13/1591 16/10654 6.32694821704331e-9 4.270690046504234e-8 2.3887457554143106e-8 5594/7316/6714/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 13 Hendra_virus R-HSA-9027284 Erythropoietin activates RAS 12/1591 14/10654 8.047909847963383e-9 5.377467034775533e-8 3.007804690652981e-8 4893/6464/4067/3717/2057/2885/2056/7409/8660/3845/3265/1399 12 Hendra_virus R-HSA-918233 TRAF3-dependent IRF activation pathway 12/1591 14/10654 8.047909847963383e-9 5.377467034775533e-8 3.007804690652981e-8 3665/29110/57506/7706/23586/1387/2033/64135/3661/7187/9641/3456 12 Hendra_virus R-HSA-111885 Opioid Signalling 36/1591 91/10654 8.177148824822556e-9 5.436365776502634e-8 3.0407488092304984e-8 2788/818/815/5321/54331/59345/817/5578/5594/10681/51764/94235/5528/55970/5443/10768/2792/5519/4988/2793/2785/2783/2784/2782/816/2786/5580/1385/5518/801/1020/2791/2790/5515/2787/5516 36 Hendra_virus R-HSA-8984722 Interleukin-35 Signalling 11/1591 12/10654 8.2905206109115e-9 5.456894909570107e-8 3.0522314686937865e-8 10148/3592/6775/3595/6774/6772/3717/9466/3716/7297/3572 11 Hendra_virus R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 11/1591 12/10654 8.2905206109115e-9 5.456894909570107e-8 3.0522314686937865e-8 5295/5290/5291/4067/23533/3717/5294/2057/2056/8660/5293 11 Hendra_virus R-HSA-5218921 VEGFR2 mediated cell proliferation 15/1591 21/10654 8.578065551970312e-9 5.618208279830061e-8 3.142459657652491e-8 5170/5590/4893/5335/5579/7422/5578/5921/10768/6714/5580/3791/3845/3265/801 15 Hendra_virus R-HSA-451326 Activation of kainate receptors upon glutamate binding 19/1591 32/10654 9.067869905963271e-9 5.909749697334684e-8 3.305528931237843e-8 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/1742/801/2791/2790/2787 19 Hendra_virus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 16/1591 24/10654 1.2726800467256781e-8 8.253704420676824e-8 4.6165844832205974e-8 596/1839/2309/5747/207/5594/1027/1950/10000/595/208/7514/1385/2353/1956/5595 16 Hendra_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 57/1591 182/10654 1.3909883943941736e-8 8.97696412577313e-8 5.02112883830092e-8 6095/23468/5905/5241/5468/1029/1786/6045/51588/3090/8517/332/5465/54780/5970/4792/6996/9759/6790/5111/2099/1387/10401/1616/2908/2033/23512/8243/9126/142/7428/3066/3065/7157/6256/7329/5371/7376/8924/4152/672/7158/10155/367/10499/9063/25942/9641/6117/648/8648/7421/4791/10891/10062/4193/8554 57 Hendra_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 28/1591 63/10654 1.8378073728304535e-8 1.1751577883950168e-7 6.57306699480206e-8 1147/3665/11035/6737/4790/1499/8737/29110/8517/6778/4615/7098/9208/5591/7316/5970/4792/1387/5437/2033/22954/3661/6233/7311/3551/4791/7314/148022 28 Hendra_virus R-HSA-420092 Glucagon-type ligand receptors 19/1591 33/10654 1.8386822539513868e-8 1.1751577883950168e-7 6.57306699480206e-8 2788/2692/54331/59345/10681/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 19 Hendra_virus R-HSA-6802952 Signaling by BRAF and RAF fusions 29/1591 67/10654 2.1329034997888608e-8 1.3566496779907035e-7 7.588214374248832e-8 27044/818/815/8805/4893/5604/10018/55750/817/3674/5594/409/10533/6714/5605/3717/2244/2335/1445/816/5894/2266/2243/60/3845/3265/369/801/5595 29 Hendra_virus R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 13/1591 17/10654 2.319509681048353e-8 1.4633928086248593e-7 8.18526589858198e-8 23643/7186/8737/356/355/841/7099/929/8772/353376/8717/8743/148022 13 Hendra_virus R-HSA-1250196 SHC1 events in ERBB2 signaling 15/1591 22/10654 2.322845727975967e-8 1.4633928086248593e-7 8.18526589858198e-8 1839/4893/6464/2065/5578/2064/1950/3084/2066/2885/5580/1956/5581/3845/3265 15 Hendra_virus R-HSA-6802957 Oncogenic MAPK signaling 30/1591 71/10654 2.3985510106460692e-8 1.5039255862960899e-7 8.411979847763466e-8 27044/818/815/8805/4893/5604/10018/55750/817/3674/5594/409/10533/6714/5605/3717/2244/2335/1445/816/5894/2266/2243/60/3845/3265/369/801/5245/5595 30 Hendra_virus R-HSA-1268020 Mitochondrial protein import 28/1591 64/10654 2.8056283656622208e-8 1.7457207998144805e-7 9.764424730632771e-8 90639/10063/56942/26520/3313/7416/400916/10440/54927/10165/1678/3329/56993/26521/25813/100272147/10469/4580/8604/26517/92609/10651/80273/9804/54543/388753/2671/131474 28 Hendra_virus R-HSA-6806834 Signaling by MET 32/1591 79/10654 2.8105709021956487e-8 1.7457207998144805e-7 9.764424730632771e-8 5295/4893/6464/5290/85440/5770/5747/3082/9101/3688/7316/6774/4233/6714/3673/867/9146/2335/5771/3914/3913/6233/2885/1398/7311/3845/3265/1399/5781/53916/7314/5879 32 Hendra_virus R-HSA-5654736 Signaling by FGFR1 24/1591 50/10654 3.0326284236574834e-8 1.8748445815415188e-7 1.0486659035077278e-7 5295/4893/6464/5290/5335/5594/8074/10817/2260/7316/6714/867/2247/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 24 Hendra_virus R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 12/1591 15/10654 3.4737867269769416e-8 2.0890090180865882e-7 1.1684555354376987e-7 1499/5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 12 Hendra_virus R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 12/1591 15/10654 3.4737867269769416e-8 2.0890090180865882e-7 1.1684555354376987e-7 1499/5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 12 Hendra_virus R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 12/1591 15/10654 3.4737867269769416e-8 2.0890090180865882e-7 1.1684555354376987e-7 1499/5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 12 Hendra_virus R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 12/1591 15/10654 3.4737867269769416e-8 2.0890090180865882e-7 1.1684555354376987e-7 1499/5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 12 Hendra_virus R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 12/1591 15/10654 3.4737867269769416e-8 2.0890090180865882e-7 1.1684555354376987e-7 1499/5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 12 Hendra_virus R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 12/1591 15/10654 3.4737867269769416e-8 2.0890090180865882e-7 1.1684555354376987e-7 1499/5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 12 Hendra_virus R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 17/1591 28/10654 3.494986418018345e-8 2.0922475253566834e-7 1.170266945399808e-7 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Hendra_virus R-HSA-187687 Signalling to ERKs 19/1591 34/10654 3.585408976841873e-8 2.1367099443071163e-7 1.1951363256139576e-7 4893/6464/5604/5594/9261/6714/5605/1432/4914/4803/5603/2885/1398/3845/5600/3265/1399/6300/5595 19 Hendra_virus R-HSA-1839124 FGFR1 mutant receptor activation 18/1591 31/10654 3.659891743119443e-8 2.161623560779921e-7 1.2090713794233874e-7 5295/8805/11052/26127/5290/613/8074/2260/9208/6776/6774/6772/399687/2247/2885/6777/7750/1523 18 Hendra_virus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 18/1591 31/10654 3.659891743119443e-8 2.161623560779921e-7 1.2090713794233874e-7 3725/5601/1849/5594/5528/9261/5519/1432/1385/2353/5518/1386/6197/5599/5600/5595/5515/5516 18 Hendra_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 40/1591 112/10654 3.769940554902679e-8 2.2167250462827753e-7 1.2398915602791034e-7 5295/8454/1147/5777/8945/4893/4790/6885/5579/5966/4690/5336/640/6500/8517/7316/5970/4792/6850/10768/8915/5715/4067/23291/5698/2534/5702/695/6233/2885/7409/7311/5293/118788/3845/3265/3551/801/5696/7314 40 Hendra_virus R-HSA-209543 p75NTR recruits signalling complexes 11/1591 13/10654 4.656253195031643e-8 2.725762379215426e-7 1.5246138780192104e-7 8767/8878/4615/7316/4803/3654/7189/6233/7311/3551/7314 11 Hendra_virus R-HSA-2990846 SUMOylation 57/1591 188/10654 5.004147643806853e-8 2.9165142435050517e-7 1.6313080424744806e-7 6095/23468/5905/5241/5468/1029/1786/6045/51588/3090/8517/332/5465/54780/5970/4792/6996/9759/6790/5111/2099/1387/10401/1616/2908/2033/23512/8243/9126/142/7428/3066/3065/7157/6256/7329/5371/7376/8924/4152/672/7158/10155/367/10499/9063/25942/9641/6117/648/8648/7421/4791/10891/10062/4193/8554 57 Hendra_virus R-HSA-2586552 Signaling by Leptin 10/1591 11/10654 5.1226504658344354e-8 2.9596937014957216e-7 1.655459817918998e-7 3667/3953/9021/3952/6776/6774/3717/8660/6777/5781 10 Hendra_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 30/1591 73/10654 5.145348082721209e-8 2.9596937014957216e-7 1.655459817918998e-7 57154/5590/892/7027/7321/6497/10273/4738/3726/64750/7323/54778/7316/6667/4609/23327/867/4088/142/3065/9040/4087/6233/7514/7048/1025/7311/387/7040/7314 30 Hendra_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 30/1591 73/10654 5.145348082721209e-8 2.9596937014957216e-7 1.655459817918998e-7 8454/57154/7291/10273/6500/7316/9978/865/11059/579/6772/2099/5715/2932/6502/2908/5698/2101/1749/55294/4488/5702/6233/7311/860/1750/133522/5696/10891/7314 30 Hendra_virus R-HSA-69242 S Phase 51/1591 161/10654 5.301394850358109e-8 3.036253414296008e-7 1.6982823330151517e-7 8454/1017/6118/11065/902/246184/7027/7321/207/8697/1027/6500/898/5925/8881/7316/5422/9978/1869/4174/5753/890/1026/5111/4609/51433/5715/2932/6502/5698/10000/8243/9126/595/5702/8900/51529/7324/64682/29945/10393/208/6233/51434/51343/7311/6117/29882/5696/7314/996 51 Hendra_virus R-HSA-4086398 Ca2+ pathway 27/1591 62/10654 5.5828538233533146e-8 3.1836705208174287e-7 1.780737857448902e-7 2788/51176/815/54331/6885/1499/59345/51701/5578/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/7474/4343/3845/801/2791/2790/2787 27 Hendra_virus R-HSA-5696394 DNA Damage Recognition in GG-NER 20/1591 38/10654 6.065919903654576e-8 3.4442970096716757e-7 1.9265153342078913e-7 9318/8450/7316/9978/64708/10980/1642/10920/142/10987/6233/2873/7311/60/8533/5887/50813/7314/51138/8451 20 Hendra_virus R-HSA-112399 IRS-mediated signalling 23/1591 48/10654 6.132273238499178e-8 3.467092946382228e-7 1.9392658959356377e-7 5295/54106/5170/4893/5290/3667/5291/2322/8074/57761/2260/5140/2263/2261/2247/208/2885/8660/5296/117145/3845/3265/5781 23 Hendra_virus R-HSA-453279 Mitotic G1-G1/S phases 48/1591 149/10654 7.279033803279863e-8 4.097941158186918e-7 2.2921212827349353e-7 8454/1017/6118/25/894/902/1029/7027/8317/207/1027/6500/898/5925/7316/5422/1869/4174/891/5753/890/1026/5111/6714/4609/1031/5715/5519/4067/3717/6502/5698/10000/595/5702/3065/8900/896/208/6233/7311/5518/6117/1859/5696/7314/5515/5516 48 Hendra_virus R-HSA-74752 Signaling by Insulin receptor 31/1591 78/10654 7.795437622011554e-8 4.370069480475121e-7 2.4443321357154875e-7 5295/54106/5170/3643/4893/6464/5290/3667/5291/526/5594/2322/8074/57761/2260/5140/2263/2261/2247/529/3630/208/2885/8660/5296/117145/3845/3265/528/5781/5595 31 Hendra_virus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 33/1591 86/10654 8.146965328708846e-8 4.5287542562528585e-7 2.5330900601867843e-7 8454/1017/8945/11065/246184/7321/991/8697/6500/8881/7316/891/890/6790/51433/5715/6502/5698/5702/8900/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/5696/7314/996 33 Hendra_virus R-HSA-453276 Regulation of mitotic cell cycle 33/1591 86/10654 8.146965328708846e-8 4.5287542562528585e-7 2.5330900601867843e-7 8454/1017/8945/11065/246184/7321/991/8697/6500/8881/7316/891/890/6790/51433/5715/6502/5698/5702/8900/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/5696/7314/996 33 Hendra_virus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 14/1591 21/10654 1.0735905175462365e-7 5.942929936040464e-7 3.324087794913034e-7 1147/11035/4790/8737/29110/8517/4615/7098/5970/4792/3661/3551/4791/148022 14 Hendra_virus R-HSA-8940973 RUNX2 regulates osteoblast differentiation 15/1591 24/10654 1.3224196746484852e-7 7.289838456499775e-7 4.077460663499496e-7 25/8841/23462/5594/3280/5925/10013/865/4094/10413/6714/7525/367/860/5595 15 Hendra_virus R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 16/1591 27/10654 1.4415255674373634e-7 7.899055010221638e-7 4.41821671017688e-7 23643/7186/842/8737/356/355/841/7099/836/929/8772/353376/8717/26060/8743/148022 16 Hendra_virus R-HSA-4090294 SUMOylation of intracellular receptors 17/1591 30/10654 1.4448762754902768e-7 7.899055010221638e-7 4.41821671017688e-7 6095/5241/5468/51588/5465/9759/2099/10401/2908/6256/7329/7376/367/9063/7421/10062/8554 17 Hendra_virus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 31/1591 80/10654 1.543959737897828e-7 8.406003017443731e-7 4.701770395244414e-7 8454/1017/8945/11065/246184/7321/991/8697/6500/8881/7316/891/890/51433/5715/5698/5702/8900/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/5696/7314/996 31 Hendra_virus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 32/1591 84/10654 1.5561295839660823e-7 8.437538686832487e-7 4.719409393995495e-7 9318/6118/902/7336/8450/54778/7316/9978/64708/5111/10980/10401/1642/10920/142/10987/7329/6233/51426/2873/2968/7311/60/8533/5887/6117/7334/50813/7314/51138/8451/8554 32 Hendra_virus R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 11/1591 14/10654 1.877828129922783e-7 9.89787496369658e-7 5.536226359134898e-7 5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 11 Hendra_virus R-HSA-4839744 truncated APC mutants destabilize the destruction complex 11/1591 14/10654 1.877828129922783e-7 9.89787496369658e-7 5.536226359134898e-7 5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 11 Hendra_virus R-HSA-4839748 AMER1 mutants destabilize the destruction complex 11/1591 14/10654 1.877828129922783e-7 9.89787496369658e-7 5.536226359134898e-7 5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 11 Hendra_virus R-HSA-5467337 APC truncation mutants have impaired AXIN binding 11/1591 14/10654 1.877828129922783e-7 9.89787496369658e-7 5.536226359134898e-7 5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 11 Hendra_virus R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 11/1591 14/10654 1.877828129922783e-7 9.89787496369658e-7 5.536226359134898e-7 5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 11 Hendra_virus R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 11/1591 14/10654 1.877828129922783e-7 9.89787496369658e-7 5.536226359134898e-7 5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 11 Hendra_virus R-HSA-8983432 Interleukin-15 signaling 11/1591 14/10654 1.877828129922783e-7 9.89787496369658e-7 5.536226359134898e-7 6464/3561/6776/3560/6774/3718/2885/3716/6777/3600/3601 11 Hendra_virus R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 38/1591 110/10654 2.2301149005949571e-7 1.1708103228123525e-6 6.548750104921699e-7 1017/3725/11065/4790/246184/1029/7321/8697/5594/1027/1051/3576/8881/7316/890/6774/5970/1026/51433/1031/3552/8900/51529/7324/64682/29945/10393/6233/51434/2353/51343/7311/6197/29882/3569/7314/996/5595 38 Hendra_virus R-HSA-2197563 NOTCH2 intracellular domain regulates transcription 10/1591 12/10654 2.659064248955092e-7 1.3795850985755242e-6 7.716500173438306e-7 2208/55534/3280/84441/10046/2033/9794/1385/388585/3516 10 Hendra_virus R-HSA-389359 CD28 dependent Vav1 pathway 10/1591 12/10654 2.659064248955092e-7 1.3795850985755242e-6 7.716500173438306e-7 941/2534/998/942/2885/7409/3932/5062/940/5879 10 Hendra_virus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 10/1591 12/10654 2.659064248955092e-7 1.3795850985755242e-6 7.716500173438306e-7 1147/8737/57506/841/7706/8517/23586/64135/8772/3551 10 Hendra_virus R-HSA-2871837 FCERI mediated NF-kB activation 31/1591 82/10654 2.964574306614542e-7 1.5320827373636872e-6 8.569472605057661e-7 8454/1147/5170/8945/4790/6885/7321/6500/23118/8517/7316/7335/5970/4792/8915/7322/5715/4067/23291/5698/10454/5702/7189/6233/7311/7334/3551/5696/997/7314/257397 31 Hendra_virus R-HSA-110056 MAPK3 (ERK1) activation 9/1591 10/10654 3.1382142375777353e-7 1.6030337591951133e-6 8.966326393079245e-7 5604/3717/3716/3570/7297/5781/3569/3572/5595 9 Hendra_virus R-HSA-2562578 TRIF-mediated programmed cell death 9/1591 10/10654 3.1382142375777353e-7 1.6030337591951133e-6 8.966326393079245e-7 23643/11035/8737/841/7099/929/8772/353376/148022 9 Hendra_virus R-HSA-450341 Activation of the AP-1 family of transcription factors 9/1591 10/10654 3.1382142375777353e-7 1.6030337591951133e-6 8.966326393079245e-7 3725/5601/5594/1432/2353/1386/5599/5600/5595 9 Hendra_virus R-HSA-418597 G alpha (z) signalling events 22/1591 48/10654 3.182727804422803e-7 1.6133137491384552e-6 9.023825958899901e-7 2788/54331/5579/59345/5578/10681/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/5580/5581/2791/2790/2787 22 Hendra_virus R-HSA-73893 DNA Damage Bypass 22/1591 48/10654 3.182727804422803e-7 1.6133137491384552e-6 9.023825958899901e-7 6118/7320/9636/7706/8450/7316/9978/5111/10459/7415/1642/25898/7398/9246/57599/6233/51426/7311/7318/6117/7314/8451 22 Hendra_virus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 12/1591 17/10654 3.522318907098614e-7 1.7651620886710101e-6 9.873166633533993e-7 1147/11035/4790/8737/8517/4615/7098/5970/4792/3551/4791/148022 12 Hendra_virus R-HSA-196299 Beta-catenin phosphorylation cascade 12/1591 17/10654 3.522318907098614e-7 1.7651620886710101e-6 9.873166633533993e-7 1499/5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 12 Hendra_virus R-HSA-9034015 Signaling by NTRK3 (TRKC) 12/1591 17/10654 3.522318907098614e-7 1.7651620886710101e-6 9.873166633533993e-7 5295/4908/4893/6464/5290/3667/5335/6714/2885/3845/3265/4916 12 Hendra_virus R-HSA-1226099 Signaling by FGFR in disease 26/1591 63/10654 3.5977490420059535e-7 1.796159238707123e-6 1.0046544494658134e-6 5295/8805/4893/11052/26127/5290/5335/5430/613/8074/2260/9208/6776/6774/2263/6772/399687/2261/5437/2247/2885/3845/6777/3265/7750/1523 26 Hendra_virus R-HSA-167044 Signalling to RAS 13/1591 20/10654 4.852891789414544e-7 2.413675126840392e-6 1.3500526030702113e-6 4893/6464/9261/6714/1432/4914/4803/5603/2885/3845/5600/3265/6300 13 Hendra_virus R-HSA-177929 Signaling by EGFR 22/1591 49/10654 4.966667952014429e-7 2.4610118728520937e-6 1.3765296945657968e-6 5295/1839/4893/6464/5290/5335/7316/1950/6714/867/9146/1445/998/6233/2885/7311/1956/3845/3265/5781/10252/7314 22 Hendra_virus R-HSA-1251985 Nuclear signaling by ERBB4 17/1591 32/10654 5.061279645462863e-7 2.489246457601252e-6 1.3923222816514937e-6 1839/2670/5241/23118/51741/23385/348/6776/10413/6714/2099/1447/3084/2066/3925/6285/6387 17 Hendra_virus R-HSA-8941326 RUNX2 regulates bone development 17/1591 32/10654 5.061279645462863e-7 2.489246457601252e-6 1.3923222816514937e-6 25/8841/23462/5594/3280/4086/5925/10013/865/4094/9759/10413/6714/7525/367/860/5595 17 Hendra_virus R-HSA-5654732 Negative regulation of FGFR3 signaling 16/1591 29/10654 5.568805197598516e-7 2.7186454894549213e-6 1.520633153587787e-6 5594/8074/7316/6714/2261/867/2247/6233/2885/7311/5518/5781/7314/5595/5515/5516 16 Hendra_virus R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 16/1591 29/10654 5.568805197598516e-7 2.7186454894549213e-6 1.520633153587787e-6 2308/2309/4303/4287/114907/5443/84676/4088/2908/3630/3066/3065/4087/56729/25942/10891 16 Hendra_virus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 14/1591 23/10654 5.610983094100749e-7 2.7291656740791513e-6 1.5265174594244686e-6 7321/6497/64750/7323/54778/7316/23327/4088/142/3065/4087/6233/7311/7314 14 Hendra_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 23/1591 53/10654 5.796012226157662e-7 2.808836694214867e-6 1.5710802371269853e-6 596/10018/1029/7027/842/572/7532/207/10971/5594/7533/841/1869/6774/4836/598/836/10000/7157/208/840/5599/5595 23 Hendra_virus R-HSA-937039 IRAK1 recruits IKK complex 11/1591 15/10654 6.086564137291763e-7 2.928190674049819e-6 1.6378390769439654e-6 1147/8517/7316/7335/3654/7189/6233/7311/7334/3551/7314 11 Hendra_virus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 11/1591 15/10654 6.086564137291763e-7 2.928190674049819e-6 1.6378390769439654e-6 1147/8517/7316/7335/3654/7189/6233/7311/7334/3551/7314 11 Hendra_virus R-HSA-447115 Interleukin-12 family signaling 24/1591 57/10654 6.498947262530252e-7 3.1152562421476534e-6 1.7424713674899953e-6 10148/3592/3593/6775/3595/4478/3313/6774/6772/149233/6950/3717/9466/3458/998/3716/3594/302/51561/246778/7297/5062/3586/3572 24 Hendra_virus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 18/1591 36/10654 7.60931158740261e-7 3.6343390722504163e-6 2.0328124818331883e-6 4893/5604/3674/5594/409/6714/5605/2244/2335/1445/5894/2266/2243/60/3845/3265/369/5595 18 Hendra_virus R-HSA-2172127 DAP12 interactions 20/1591 43/10654 8.175295602674726e-7 3.876672430945757e-6 2.1683579734692823e-6 5295/4893/6464/5290/5335/5291/5336/54209/6850/54210/2534/695/2885/7410/3133/3932/5296/3845/3265/5879 20 Hendra_virus R-HSA-5696395 Formation of Incision Complex in GG-NER 20/1591 43/10654 8.175295602674726e-7 3.876672430945757e-6 2.1683579734692823e-6 6118/902/7336/8450/54778/7316/9978/10401/1642/142/7329/6233/2968/7311/5887/6117/7334/7314/8451/8554 20 Hendra_virus R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 12/1591 18/10654 9.126183303339248e-7 4.312121610827794e-6 2.4119198730253726e-6 1839/4893/5578/5594/4314/2885/1385/1956/6197/3845/3265/5595 12 Hendra_virus R-HSA-69052 Switching of origins to a post-replicative state 32/1591 90/10654 9.586563452560862e-7 4.5135314760633525e-6 2.5245754287882698e-6 8454/1017/11065/246184/7321/8697/6500/898/8881/7316/9978/4174/890/51433/5715/6502/5698/5702/8900/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/5696/7314/996 32 Hendra_virus R-HSA-5357786 TNFR1-induced proapoptotic signaling 10/1591 13/10654 9.970527347128168e-7 4.6776622979611936e-6 2.6163795166222853e-6 7124/7186/8737/841/7128/7132/9099/8772/8717/1540 10 Hendra_virus R-HSA-400253 Circadian Clock 27/1591 70/10654 1.0778195441082652e-6 5.038711154965495e-6 2.818326723109952e-6 8454/6095/26224/8945/8841/10135/28999/6500/3091/200186/5465/7316/8553/1387/2908/2033/6256/10498/6233/1385/7311/10499/1386/23411/8648/10891/7314 27 Hendra_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 13/1591 21/10654 1.0994256356200533e-6 5.121620126497643e-6 2.864700599855068e-6 4893/4790/5970/1387/4067/2534/2033/5894/30835/5971/3845/3265/5062 13 Hendra_virus R-HSA-354192 Integrin alphaIIb beta3 signaling 15/1591 27/10654 1.1259605211031895e-6 5.208551641326992e-6 2.913324425232029e-6 5170/6464/5770/5747/207/3674/6850/6714/2244/2335/1445/2885/1398/2266/2243 15 Hendra_virus R-HSA-9006921 Integrin signaling 15/1591 27/10654 1.1259605211031895e-6 5.208551641326992e-6 2.913324425232029e-6 5170/6464/5770/5747/207/3674/6850/6714/2244/2335/1445/2885/1398/2266/2243 15 Hendra_virus R-HSA-3371571 HSF1-dependent transactivation 14/1591 24/10654 1.1614971881333882e-6 5.3542187452978134e-6 2.9948011122603037e-6 818/815/817/84335/64223/1387/3320/2033/816/3326/2475/3312/3297/57521 14 Hendra_virus R-HSA-109704 PI3K Cascade 20/1591 44/10654 1.2896135437329158e-6 5.9036633853240405e-6 3.302124644852449e-6 5295/54106/5170/5290/3667/5291/2322/8074/57761/2260/5140/2263/2261/2247/208/2885/8660/5296/117145/5781 20 Hendra_virus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 20/1591 44/10654 1.2896135437329158e-6 5.9036633853240405e-6 3.302124644852449e-6 892/7027/7321/6497/3726/64750/7323/54778/7316/6667/4609/23327/4088/142/3065/4087/6233/1025/7311/7314 20 Hendra_virus R-HSA-9609507 Protein localization 48/1591 163/10654 1.4393729381587145e-6 6.566518610979239e-6 3.6728826697843065e-6 1891/351/90639/10063/7321/51/10965/56942/26520/3313/7416/7323/7316/400916/10440/54927/10165/1678/3329/7322/56993/1962/3416/26521/25813/100272147/118424/10469/4580/8604/4843/10455/26517/92609/10651/8540/6233/4358/6844/80273/9804/7311/54543/388753/2671/3162/131474/7314 48 Hendra_virus R-HSA-6807070 PTEN Regulation 43/1591 140/10654 1.4758443467444027e-6 6.709766566126614e-6 3.7530062425802683e-6 3725/8841/5468/1822/23186/2146/10273/207/6045/5594/1460/7316/4734/57167/64223/10014/5715/1958/5698/10000/23512/5728/6009/6615/5702/3066/3065/7157/23028/8975/5371/208/6233/2475/7311/1386/4343/648/57521/5696/23608/7314/5595 43 Hendra_virus R-HSA-9020956 Interleukin-27 signaling 9/1591 11/10654 1.4954985597052077e-6 6.729743518673435e-6 3.7641800482375978e-6 10148/6774/6772/3717/9466/3716/246778/7297/3572 9 Hendra_virus R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 9/1591 11/10654 1.4954985597052077e-6 6.729743518673435e-6 3.7641800482375978e-6 627/4893/4915/10817/4909/2885/3845/3265/5781 9 Hendra_virus R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 9/1591 11/10654 1.4954985597052077e-6 6.729743518673435e-6 3.7641800482375978e-6 6885/23118/7316/10454/7189/6233/7311/7314/257397 9 Hendra_virus R-HSA-3858494 Beta-catenin independent WNT signaling 44/1591 146/10654 1.978285027330682e-6 8.8721053937576e-6 4.962477695676964e-6 2788/57154/51176/1173/815/54331/6885/5579/1499/59345/51701/5578/10681/409/51764/94235/64750/7316/55970/5216/2792/5715/2793/5698/2785/2783/2784/2782/5702/2786/6233/7474/163/7311/387/4343/3845/801/2791/5696/7314/5879/2790/2787 44 Hendra_virus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 27/1591 72/10654 2.0543499945594105e-6 9.182111631088175e-6 5.135874986398526e-6 1017/11065/246184/7321/8697/898/8881/7316/890/51433/5715/5698/5702/8900/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/5696/7314/996 27 Hendra_virus R-HSA-9012852 Signaling by NOTCH3 21/1591 49/10654 2.293446766785236e-6 1.0216262870225141e-5 5.7143118094985674e-6 142678/23462/55534/3280/84441/23385/10046/7316/1950/4854/6772/8850/1387/2033/9794/6233/7311/1956/388585/3516/7314 21 Hendra_virus R-HSA-9613829 Chaperone Mediated Autophagy 13/1591 22/10654 2.3197472540586546e-6 1.0298743681609396e-5 5.760446201353706e-6 2670/1915/1080/10013/7316/3920/3320/6233/3326/7311/7431/3312/7314 13 Hendra_virus R-HSA-3371556 Cellular response to heat stress 31/1591 89/10654 2.3389767586332475e-6 1.0349385457096277e-5 5.7887719109986725e-6 818/6118/815/1915/817/5594/3308/84335/10013/545/472/3313/9261/7415/64223/2932/1387/3310/3320/2033/6767/816/22824/3326/2475/23411/6117/3312/3297/57521/5595 31 Hendra_virus R-HSA-5654738 Signaling by FGFR2 27/1591 73/10654 2.801363173745891e-6 1.2326395370198793e-5 6.8945824444044645e-6 5295/4893/6464/5290/5335/5430/5594/8074/10817/7316/2263/6714/867/5437/4670/2247/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 27 Hendra_virus R-HSA-8943724 Regulation of PTEN gene transcription 24/1591 61/10654 2.8044179942780323e-6 1.2326395370198793e-5 6.8945824444044645e-6 3725/8841/5468/1822/23186/2146/6045/5594/57167/64223/10014/1958/23512/6009/6615/3066/3065/7157/23028/2475/1386/648/57521/5595 24 Hendra_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 16/1591 32/10654 3.155986915351928e-6 1.3825730758313247e-5 7.733212971392141e-6 57154/10273/4738/64750/7316/23327/867/4088/9040/4087/6233/7514/7048/7311/7040/7314 16 Hendra_virus R-HSA-1236975 Antigen processing-Cross presentation 33/1591 99/10654 3.3914063049702943e-6 1.4808021589028713e-5 8.282642460983557e-6 23643/1147/3135/3107/6890/10333/7099/8517/4615/7316/7096/3106/5715/929/5698/114609/2923/5702/695/6233/948/4012/3685/7311/3133/3134/7097/3551/1536/3105/5696/7314/4360 33 Hendra_virus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 22/1591 54/10654 3.669807094076478e-6 1.5970903899549937e-5 8.93308305794932e-6 9318/902/5430/8450/7316/9978/64708/10980/5437/1642/10920/2033/10987/6233/2873/2968/7311/8533/50813/7314/51138/8451 22 Hendra_virus R-HSA-186797 Signaling by PDGF 23/1591 58/10654 3.845036716173098e-6 1.6678634673760685e-5 9.328941540878992e-6 5295/4893/5290/5335/5291/4690/5921/6778/6776/6774/6772/6714/5159/2885/1398/5155/5296/3845/6777/3265/1399/5781/5156 23 Hendra_virus R-HSA-1236974 ER-Phagosome pathway 29/1591 83/10654 4.5811760974783105e-6 1.9786250508778004e-5 1.1067139362430629e-5 23643/1147/3135/3107/6890/10333/7099/8517/4615/7316/7096/3106/5715/929/5698/114609/2923/5702/695/6233/948/7311/3133/3134/7097/3551/3105/5696/7314 29 Hendra_virus R-HSA-112409 RAF-independent MAPK1/3 activation 13/1591 23/10654 4.605990882101819e-6 1.9786250508778004e-5 1.1067139362430629e-5 1844/5604/1849/5594/5605/3717/3716/3570/7297/5781/3569/3572/5595 13 Hendra_virus R-HSA-622312 Inflammasomes 12/1591 20/10654 4.621278463501438e-6 1.9786250508778004e-5 1.1067139362430629e-5 834/596/351/4790/10910/58484/7295/5970/598/3326/114548/4791 12 Hendra_virus R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 12/1591 20/10654 4.621278463501438e-6 1.9786250508778004e-5 1.1067139362430629e-5 23462/55534/3280/84441/10046/8850/1387/4088/2033/9794/388585/3516 12 Hendra_virus R-HSA-210990 PECAM1 interactions 9/1591 12/10654 5.18427496413432e-6 2.2125147669515178e-005 1.237536604341741e-5 5777/5335/6714/4067/2534/7525/3685/3932/5781 9 Hendra_virus R-HSA-5674135 MAP2K and MAPK activation 18/1591 40/10654 5.226390168530359e-6 2.223316460760664e-5 1.2435783680747478e-5 4893/5604/3674/5594/409/6714/5605/2244/2335/1445/5894/2266/2243/60/3845/3265/369/5595 18 Hendra_virus R-HSA-1980145 Signaling by NOTCH2 16/1591 33/10654 5.280170811411283e-6 2.2247343896487664e-5 1.2443714651096653e-5 2208/142678/55534/3280/84441/23385/10046/7316/2033/9794/6233/1385/7311/388585/3516/7314 16 Hendra_virus R-HSA-2559585 Oncogene Induced Senescence 16/1591 33/10654 5.280170811411283e-6 2.2247343896487664e-5 1.2443714651096653e-5 1029/7027/5594/5925/7316/1869/6667/1031/7157/6233/7311/4343/2113/7314/5595/4193 16 Hendra_virus R-HSA-5654726 Negative regulation of FGFR1 signaling 16/1591 33/10654 5.280170811411283e-6 2.2247343896487664e-5 1.2443714651096653e-5 5594/8074/2260/7316/6714/867/2247/6233/2885/7311/5518/5781/7314/5595/5515/5516 16 Hendra_virus R-HSA-8878171 Transcriptional regulation by RUNX1 62/1591 239/10654 5.310603279039598e-6 2.2304533771966312e-5 1.2475702941235881e-5 6595/25/894/3562/902/1437/5579/6597/640/3674/6045/9021/2625/1460/1378/4005/6938/6598/6599/200845/7316/865/5079/10398/10413/6714/2099/122809/5715/8850/1387/3558/5698/10138/2033/6605/595/50943/4602/3458/5702/3065/83737/861/896/5371/6233/7311/6688/860/25942/4343/648/3276/3977/6601/3559/5781/1493/5696/7314/55170 62 Hendra_virus R-HSA-5689880 Ub-specific processing proteases 58/1591 220/10654 6.221448923407198e-6 2.604739533439153e-5 1.4569215833295339e-5 8295/23326/7186/6885/90865/991/8737/2625/9817/4303/91833/57646/409/6478/4086/1080/330/3091/9101/11274/8517/64750/7416/7316/890/7417/4792/8678/4609/23586/5715/3416/329/6502/9099/4088/5698/9146/64135/5728/10454/5702/7157/8900/8975/4087/63891/7189/57599/6233/9804/7311/367/1540/154/5696/7314/4193 58 Hendra_virus R-HSA-6804758 Regulation of TP53 Activity through Acetylation 15/1591 30/10654 6.440432195869931e-6 2.6879153927873558e-5 1.5034447397298893e-5 23774/64769/7862/207/84289/27154/10000/2033/7994/3066/3065/7157/5371/208/5300 15 Hendra_virus R-HSA-1169408 ISG15 antiviral mechanism 26/1591 72/10654 7.105400130119466e-6 2.9468477655636533e-5 1.6482746383349233e-5 5335/4600/9636/11274/25820/7706/7316/4734/3434/6772/23586/3661/7324/3836/9246/51191/4599/6233/3716/7311/7318/5610/5300/7334/7314/5595 26 Hendra_virus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 26/1591 72/10654 7.105400130119466e-6 2.9468477655636533e-5 1.6482746383349233e-5 11065/246184/7321/991/8697/8881/7316/6790/51433/5715/6502/5698/5702/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/5696/7314/996 26 Hendra_virus R-HSA-5696398 Nucleotide Excision Repair 35/1591 111/10654 7.1650603987249585e-6 2.9623046585978504e-5 1.6569202172051466e-5 9318/6118/902/5430/7336/8450/54778/7316/9978/64708/5111/10980/5437/10401/1642/10920/2033/142/10987/7329/6233/51426/2873/2968/7311/60/8533/5887/6117/7334/50813/7314/51138/8451/8554 35 Hendra_virus R-HSA-74749 Signal attenuation 8/1591 10/10654 8.259349809749226e-6 3.3830092254793275e-5 1.8922349409332596e-5 3643/6464/3667/5594/3630/2885/8660/5595 8 Hendra_virus R-HSA-8877330 RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) 8/1591 10/10654 8.259349809749226e-6 3.3830092254793275e-5 1.8922349409332596e-5 1378/865/3558/50943/3458/861/3559/1493 8 Hendra_virus R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 8/1591 10/10654 8.259349809749226e-6 3.3830092254793275e-5 1.8922349409332596e-5 2308/2309/4303/7295/8850/1387/2033/23411 8 Hendra_virus R-HSA-5654727 Negative regulation of FGFR2 signaling 16/1591 34/10654 8.597012332317675e-6 3.5104467023630504e-5 1.963515162319469e-5 5594/8074/7316/2263/6714/867/2247/6233/2885/7311/5518/5781/7314/5595/5515/5516 16 Hendra_virus R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 13/1591 24/10654 8.676756156791785e-6 3.532107198595548e-5 1.9756306326233604e-5 5590/5579/5578/5594/6280/6279/1432/5580/5300/5600/1536/5879/5595 13 Hendra_virus R-HSA-445144 Signal transduction by L1 12/1591 21/10654 9.317082234009965e-6 3.769571802934307e-5 2.1084528602958334e-5 5604/3674/5594/1460/2260/3688/5605/7410/3685/1956/5879/5595 12 Hendra_virus R-HSA-6807004 Negative regulation of MET activity 12/1591 21/10654 9.317082234009965e-6 3.769571802934307e-5 2.1084528602958334e-5 5770/3082/9101/7316/4233/867/9146/5771/6233/2885/7311/7314 12 Hendra_virus R-HSA-69206 G1/S Transition 39/1591 131/10654 1.0259723597685969e-5 4.138297048700773e-5 2.3146937385023225e-5 8454/1017/6118/902/7027/8317/207/1027/6500/898/5925/7316/5422/1869/4174/891/5753/890/1026/5111/4609/5715/5519/6502/5698/10000/595/5702/3065/8900/208/6233/7311/5518/6117/5696/7314/5515/5516 39 Hendra_virus R-HSA-5654733 Negative regulation of FGFR4 signaling 15/1591 31/10654 1.076172102954569e-5 4.327585690604543e-5 2.4205694716911276e-5 5594/8074/7316/6714/867/2247/6233/2885/7311/5518/5781/7314/5595/5515/5516 15 Hendra_virus R-HSA-69306 DNA Replication 38/1591 127/10654 1.167061620962576e-5 4.678856134949964e-5 2.617047271249413e-5 8454/1017/6118/11065/246184/7321/8317/8697/6500/898/8881/7316/5422/9978/1869/4174/890/5111/51433/5715/6502/5698/5702/8900/51529/7324/64682/29945/10393/6233/51434/51343/7311/6117/29882/5696/7314/996 38 Hendra_virus R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 18/1591 42/10654 1.2095052612695906e-5 4.834366950633439e-5 2.704029889243193e-5 2788/54331/59345/10681/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 18 Hendra_virus R-HSA-190236 Signaling by FGFR 29/1591 87/10654 1.3096869824506884e-5 5.219023728259821e-5 2.919181828353944e-5 5295/4893/6464/5290/5335/5430/5594/8074/10817/2260/7316/2263/6714/2261/867/5437/4670/2247/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 29 Hendra_virus R-HSA-350054 Notch-HLH transcription pathway 14/1591 28/10654 1.31648806756837e-5 5.230371511690551e-5 2.9255290390408223e-5 8841/55534/84441/10013/10046/4854/9759/10014/8850/1387/3066/3065/9794/3516 14 Hendra_virus R-HSA-171007 p38MAPK events 9/1591 13/10654 1.4605524980332584e-5 5.785362140413176e-5 3.235954636361111e-5 4893/9261/6714/1432/5603/3845/5600/3265/6300 9 Hendra_virus R-HSA-69239 Synthesis of DNA 36/1591 119/10654 1.5035544325379747e-5 5.9379179529783294e-5 3.321284418143586e-5 8454/1017/6118/11065/246184/7321/8697/6500/898/8881/7316/5422/9978/4174/890/5111/51433/5715/6502/5698/5702/8900/51529/7324/64682/29945/10393/6233/51434/51343/7311/6117/29882/5696/7314/996 36 Hendra_virus R-HSA-1296041 Activation of G protein gated Potassium channels 13/1591 25/10654 1.5609694494796228e-5 6.056195254139417e-5 3.387441034061352e-5 2788/54331/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 13 Hendra_virus R-HSA-1296059 G protein gated Potassium channels 13/1591 25/10654 1.5609694494796228e-5 6.056195254139417e-5 3.387441034061352e-5 2788/54331/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 13 Hendra_virus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 13/1591 25/10654 1.5609694494796228e-5 6.056195254139417e-5 3.387441034061352e-5 1849/5594/5528/9261/5519/1432/1385/5518/6197/5600/5595/5515/5516 13 Hendra_virus R-HSA-5654708 Downstream signaling of activated FGFR3 13/1591 25/10654 1.5609694494796228e-5 6.056195254139417e-5 3.387441034061352e-5 5295/4893/6464/5290/5335/8074/10817/2261/2247/2885/3845/3265/5781 13 Hendra_virus R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 13/1591 25/10654 1.5609694494796228e-5 6.056195254139417e-5 3.387441034061352e-5 23462/55534/3280/84441/10046/4854/6772/8850/1387/2033/9794/388585/3516 13 Hendra_virus R-HSA-997272 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits 13/1591 25/10654 1.5609694494796228e-5 6.056195254139417e-5 3.387441034061352e-5 2788/54331/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 13 Hendra_virus R-HSA-76009 Platelet Aggregation (Plug Formation) 17/1591 39/10654 1.6074129397273724e-5 6.218150056313782e-5 3.478027998240513e-5 5170/6464/5770/5747/207/3674/6850/6714/4352/2244/2335/1445/2885/1398/2266/2243/7066 17 Hendra_virus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 26/1591 75/10654 1.654223524401662e-5 6.380576451263553e-5 3.568878740691632e-5 11065/246184/7321/991/8697/8881/7316/891/890/51433/5715/5698/5702/8900/51529/7324/64682/29945/10393/6233/51434/7311/29882/5696/7314/996 26 Hendra_virus R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 15/1591 32/10654 1.747266289501078e-5 6.719864247121878e-5 3.7586542274151095e-5 5295/5777/4690/5336/640/6850/10768/4067/2534/695/2885/7409/5293/118788/801 15 Hendra_virus R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 18/1591 43/10654 1.792054105080248e-5 6.872137916003385e-5 3.84382619640401e-5 2788/54331/59345/10681/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 18 Hendra_virus R-HSA-1963640 GRB2 events in ERBB2 signaling 10/1591 16/10654 1.8109377521904446e-5 6.884685764792985e-5 3.85084464546244e-5 1839/4893/2064/1950/3084/2066/2885/1956/3845/3265 10 Hendra_virus R-HSA-1963642 PI3K events in ERBB2 signaling 10/1591 16/10654 1.8109377521904446e-5 6.884685764792985e-5 3.85084464546244e-5 5295/1839/5290/2065/2064/1950/3084/2066/2885/1956 10 Hendra_virus R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 10/1591 16/10654 1.8109377521904446e-5 6.884685764792985e-5 3.85084464546244e-5 5295/5170/6464/5290/5291/6850/4067/2534/2885/5296 10 Hendra_virus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 23/1591 63/10654 1.9332777668108594e-5 7.328729184787298e-5 4.099213602980045e-5 11065/246184/7321/8697/8881/7316/51433/5715/5698/5702/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/5696/7314/996 23 Hendra_virus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 26/1591 76/10654 2.1616816276775906e-5 8.171156552621293e-5 4.5704125842326205e-5 11065/246184/7321/991/8697/8881/7316/891/890/51433/5715/5698/5702/8900/51529/7324/64682/29945/10393/6233/51434/7311/29882/5696/7314/996 26 Hendra_virus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 25/1591 72/10654 2.319434195073553e-5 8.742482735277239e-5 4.889975226080995e-5 11065/246184/7321/991/8697/8881/7316/890/51433/5715/5698/5702/8900/51529/7324/64682/29945/10393/6233/51434/7311/29882/5696/7314/996 25 Hendra_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 28/1591 85/10654 2.354602554632691e-5 8.849827215281392e-5 4.950016734170998e-5 8454/1017/902/7027/207/1027/6500/898/5925/7316/1869/5753/890/1026/4609/5715/6502/5698/10000/595/5702/8900/208/6233/51343/7311/5696/7314 28 Hendra_virus R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 8/1591 11/10654 2.6296286476533244e-5 9.717873466048458e-5 5.435545249339274e-5 7422/3091/1387/2033/25994/2056/2034/768 8 Hendra_virus R-HSA-3371378 Regulation by c-FLIP 8/1591 11/10654 2.6296286476533244e-5 9.717873466048458e-5 5.435545249339274e-5 7186/8737/356/355/841/8772/8717/8743 8 Hendra_virus R-HSA-4755510 SUMOylation of immune response proteins 8/1591 11/10654 2.6296286476533244e-5 9.717873466048458e-5 5.435545249339274e-5 51588/8517/5970/4792/10401/7329/9641/4791 8 Hendra_virus R-HSA-5218900 CASP8 activity is inhibited 8/1591 11/10654 2.6296286476533244e-5 9.717873466048458e-5 5.435545249339274e-5 7186/8737/356/355/841/8772/8717/8743 8 Hendra_virus R-HSA-69416 Dimerization of procaspase-8 8/1591 11/10654 2.6296286476533244e-5 9.717873466048458e-5 5.435545249339274e-5 7186/8737/356/355/841/8772/8717/8743 8 Hendra_virus R-HSA-9614399 Regulation of localization of FOXO transcription factors 8/1591 11/10654 2.6296286476533244e-5 9.717873466048458e-5 5.435545249339274e-5 2308/2309/7532/207/10971/4303/10000/208 8 Hendra_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 13/1591 26/10654 2.696289091990276e-5 9.936463701122939e-5 5.557810384603912e-5 57154/10273/64750/7316/23327/4088/4087/6233/7514/7048/7311/7040/7314 13 Hendra_virus R-HSA-163359 Glucagon signaling in metabolic regulation 15/1591 33/10654 2.763307296467709e-5 1.0155154314518831e-4 5.680131664961402e-5 2788/54331/59345/51764/94235/55970/2778/2785/2783/2784/2782/2786/2791/2790/2787 15 Hendra_virus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 25/1591 73/10654 3.033391757909556e-5 1.1116834614167154e-4 6.218032966351998e-5 11065/246184/7321/991/8697/8881/7316/890/51433/5715/5698/5702/8900/51529/7324/64682/29945/10393/6233/51434/7311/29882/5696/7314/996 25 Hendra_virus R-HSA-1592230 Mitochondrial biogenesis 30/1591 95/10654 3.0671023171323114e-005 1.120932697670179e-4 6.269767167618537e-5 8841/55735/200186/3313/5465/10989/54927/84303/1432/1387/25813/4580/2101/6256/10651/10498/1385/10499/1386/6742/5600/5564/6300/801/133522/7019/8648/2746/10891/139322 30 Hendra_virus R-HSA-195721 Signaling by WNT 77/1591 331/10654 3.077528497200978e-5 1.1216446836906043e-4 6.273749553522655e-5 2788/8454/57154/51176/8945/1173/815/8295/857/54331/6885/5579/6597/1499/5525/59345/51701/5526/207/1452/5578/6500/10681/409/51764/1460/9101/94235/6657/64750/8452/5528/7316/9978/55970/51699/5216/2792/9559/4609/5715/5519/2932/10524/1387/2793/5698/2033/2785/2783/2784/5529/2782/5702/3065/2786/208/6233/5527/7474/7514/163/7311/5518/387/4343/25776/3845/801/2791/5696/7314/5879/2790/5515/2787/5516 77 Hendra_virus R-HSA-8949215 Mitochondrial calcium ion transport 12/1591 23/10654 3.20134042039694e-5 1.1617665494169088e-4 6.498165129013701e-5 10730/11331/8165/7416/7417/6687/30968/3954/221154/10367/10939/5245 12 Hendra_virus R-HSA-202733 Cell surface interactions at the vascular wall 39/1591 137/10654 3.2051760433648656e-5 1.1617665494169088e-4 6.498165129013701e-5 5295/5777/4893/6464/857/5290/5335/960/5291/483/6401/3684/7010/2888/2993/4312/6383/338/3688/6714/4067/140885/54210/682/2335/2534/2885/7525/285/3685/3932/5296/7040/3687/3845/3265/5781/3689/9046 39 Hendra_virus R-HSA-611105 Respiratory electron transport 31/1591 100/10654 3.412330203938188e-5 1.2334734589645416e-4 6.899246860421472e-5 51300/9377/4722/4723/4702/7388/4719/55863/4704/2109/51295/4729/7386/6389/6341/7385/4728/4725/10128/27089/2108/4726/7384/51204/6834/4698/1340/1327/4697/4720/51079 31 Hendra_virus R-HSA-8941856 RUNX3 regulates NOTCH signaling 9/1591 14/10654 3.545906037470591e-5 1.2712339692141849e-4 7.110454551916076e-5 55534/3280/84441/10046/8850/1387/2033/9794/3516 9 Hendra_virus R-HSA-8853659 RET signaling 17/1591 41/10654 3.547349520103086e-5 1.2712339692141849e-4 7.110454551916076e-5 5295/2674/6464/5290/5335/5291/5578/6714/8503/5979/2885/8660/5293/5296/55715/5781/9046 17 Hendra_virus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 14/1591 30/10654 3.555227275958038e-5 1.2712339692141849e-4 7.110454551916076e-5 6118/7320/8450/7316/9978/5111/1642/7398/57599/6233/7311/6117/7314/8451 14 Hendra_virus R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 14/1591 30/10654 3.555227275958038e-5 1.2712339692141849e-4 7.110454551916076e-5 818/5170/815/4893/817/5594/816/1742/1385/6197/3845/3265/801/5595 14 Hendra_virus R-HSA-8876384 Listeria monocytogenes entry into host cells 11/1591 20/10654 3.622582105564554e-5 1.2918264489654728e-4 7.225635466624716e-5 1499/7316/4233/6714/867/999/9146/6233/2885/7311/7314 11 Hendra_virus R-HSA-6788467 IL-6-type cytokine receptor ligand interactions 10/1591 17/10654 3.808718903999347e-5 1.3545524489223484e-4 7.576483841289024e-5 3589/3976/3717/3716/1270/5008/3977/7297/1489/3572 10 Hendra_virus R-HSA-69202 Cyclin E associated events during G1/S transition 27/1591 83/10654 4.210045039028758e-5 1.493267985693042e-4 8.352368173944454e-5 8454/1017/902/7027/207/1027/6500/898/5925/7316/1869/5753/890/1026/4609/5715/6502/5698/10000/595/5702/8900/208/6233/7311/5696/7314 27 Hendra_virus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 26/1591 79/10654 4.6383032633419336e-5 1.6407687747062508e-4 9.17739148361773e-5 9318/6118/902/5430/8450/7316/9978/64708/5111/10980/5437/1642/10920/2033/10987/6233/51426/2873/2968/7311/8533/6117/50813/7314/51138/8451 26 Hendra_virus R-HSA-1428517 The citric acid (TCA) cycle and respiratory electron transport 46/1591 174/10654 5.1223412988687343e-5 1.8071620102408896e-4 1.0108086829767637e-4 51300/9377/4967/4722/4723/4702/5160/5165/7388/1743/4719/55863/4704/2109/4200/1737/51295/4729/7386/8050/7416/6389/6341/7385/4728/4725/5467/682/5162/10128/27089/6256/2108/3029/4726/7384/1738/51204/6834/4698/1340/1327/4697/4720/5164/51079 46 Hendra_virus R-HSA-9006936 Signaling by TGF-beta family members 31/1591 102/10654 5.221746319222051e-5 1.8373325479603122e-4 1.0276841160171059e-4 57154/5590/892/7027/7321/6497/10273/4738/4086/3726/64750/7323/54778/7316/6667/4609/23327/867/4088/142/3065/9040/4087/6233/7514/7048/1025/7311/387/7040/7314 31 Hendra_virus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 23/1591 67/10654 5.980654250015853e-5 2.0987813190373933e-4 1.1739215238757908e-4 11065/246184/7321/991/8697/8881/7316/51433/5715/5698/5702/51529/7324/64682/29945/10393/6233/51434/7311/29882/5696/7314/996 23 Hendra_virus R-HSA-9008059 Interleukin-37 signaling 11/1591 21/10654 6.582543375944476e-5 2.3038901815805666e-4 1.2886460577245798e-4 834/5777/5783/27178/29110/6774/59307/8809/4088/5771/5781 11 Hendra_virus R-HSA-8856828 Clathrin-mediated endocytosis 40/1591 146/10654 6.610146715685276e-5 2.3074469933645437e-4 1.29063550649264e-4 9318/1173/23396/1839/4738/1601/1785/409/1080/338/7316/1950/64708/26052/10980/2017/867/9146/10920/9322/10987/29979/6233/2885/7474/2873/10096/6844/163/7311/3575/1759/1956/60/8533/3312/154/50813/7314/51138 40 Hendra_virus R-HSA-2029481 FCGR activation 8/1591 12/10654 6.852030950133128e-5 2.3730986772319706e-4 1.3273567809158417e-4 2268/919/3055/6850/6714/4067/2534/7525 8 Hendra_virus R-HSA-3371511 HSF1 activation 8/1591 12/10654 6.852030950133128e-5 2.3730986772319706e-4 1.3273567809158417e-4 6118/1915/10013/7415/3320/3326/6117/3297 8 Hendra_virus R-HSA-5689877 Josephin domain DUBs 8/1591 12/10654 6.852030950133128e-5 2.3730986772319706e-4 1.3273567809158417e-4 4287/7316/7415/9929/6233/7311/5887/7314 8 Hendra_virus R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 13/1591 28/10654 7.243524398123386e-5 2.5021364957486265e-4 1.3995321291413333e-4 10694/10575/5203/7203/10576/908/6950/7846/10574/10383/60/22948/10693 13 Hendra_virus R-HSA-844456 The NLRP3 inflammasome 9/1591 15/10654 7.688259625238872e-5 2.64884569900808e-4 1.4815916986137407e-4 834/351/4790/10910/7295/5970/3326/114548/4791 9 Hendra_virus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 14/1591 32/10654 8.590885551390416e-5 2.9521406712959796e-4 1.6512351449425738e-4 892/7027/3726/54778/7316/6667/4609/4088/3065/4087/6233/1025/7311/7314 14 Hendra_virus R-HSA-9612973 Autophagy 34/1591 119/10654 9.287687413022839e-5 3.183318768764046e-4 1.7805411102686273e-4 2670/65018/1915/8878/7249/1080/1460/10533/10013/64419/7416/192111/7316/8678/6714/64223/56993/3920/3320/6009/55054/6233/3326/2475/9804/7311/54543/55626/7431/3312/5564/57521/7248/7314 34 Hendra_virus R-HSA-983231 Factors involved in megakaryocyte development and platelet production 44/1591 168/10654 9.374553159029775e-5 3.2047891032032017e-4 1.792550216455306e-4 55582/1017/3443/23468/25/3441/85440/8165/23186/10019/2625/29127/3449/3444/832/3659/23414/1062/3451/3717/7846/3448/3440/4602/3066/3065/998/7157/23028/3439/3835/10383/60/25942/3452/3456/1020/81704/10938/3660/3446/9732/5879/3445 44 Hendra_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 26/1591 82/10654 9.423897432454108e-5 3.205094165330793e-4 1.7927208483331722e-4 8454/51176/8945/1499/5525/5526/1452/6500/5528/7316/9978/5715/5519/2932/5698/5529/5702/3065/6233/5527/7311/5518/5696/7314/5515/5516 26 Hendra_virus R-HSA-9013694 Signaling by NOTCH4 26/1591 82/10654 9.423897432454108e-5 3.205094165330793e-4 1.7927208483331722e-4 8454/23462/207/55534/3280/6500/84441/23385/10046/7316/9978/5715/8850/1387/4088/5698/2033/55294/5702/9794/6233/7311/388585/3516/5696/7314 26 Hendra_virus R-HSA-445717 Aquaporin-mediated transport 19/1591 52/10654 9.954842577544824e-5 3.376988905151744e-4 1.8888675659956849e-4 2788/54331/59345/10681/51764/94235/55970/2778/2792/282679/2793/2785/2783/2784/2782/2786/2791/2790/2787 19 Hendra_virus R-HSA-5205647 Mitophagy 13/1591 29/10654 1.1344089764590129e-4 3.838422188888169e-4 2.1469632802549092e-4 65018/8878/1460/7416/192111/7316/6714/56993/6233/9804/7311/54543/7314 13 Hendra_virus R-HSA-198753 ERK/MAPK targets 11/1591 22/10654 1.1393698330893771e-4 3.8453731866766475e-4 2.150851215525865e-4 1849/5594/5528/5519/1432/5518/6197/5600/5595/5515/5516 11 Hendra_virus R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 31/1591 106/10654 1.1637578027309303e-4 3.9176884809491626e-4 2.1912996794424644e-4 9318/1173/1839/4738/1601/409/1080/338/7316/1950/64708/10980/867/9146/10920/10987/29979/6233/2885/7474/2873/6844/163/7311/3575/1956/8533/154/50813/7314/51138 31 Hendra_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 26/1591 83/10654 1.1802145892613104e-4 3.963004826377446e-4 2.2166466904907861e-4 8454/1147/8945/4893/4790/6885/5579/5966/6500/8517/7316/5970/4792/8915/5715/23291/5698/5702/6233/7311/3845/3265/3551/801/5696/7314 26 Hendra_virus R-HSA-8853334 Signaling by FGFR3 fusions in cancer 7/1591 10/10654 1.2946209847215394e-4 4.33616091844708e-4 2.4253658954276938e-4 5295/4893/5290/2261/2885/3845/3265 7 Hendra_virus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 30/1591 102/10654 1.331302728016617e-4 4.447761386782789e-4 2.487787926091658e-4 8454/7124/1147/8945/8744/7186/356/8600/9039/6500/330/7316/9020/7133/5715/7132/329/23291/5698/5702/9040/6233/7311/5971/7187/958/5696/4791/959/7314 30 Hendra_virus R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 26/1591 84/10654 1.4701646425091132e-4 4.899314413197877e-4 2.7403572681530065e-4 6517/7124/1052/8841/4790/5468/892/1051/3952/5465/5970/1387/2033/9967/7026/6256/896/10498/9370/948/10499/7040/8202/9282/8648/10891 26 Hendra_virus R-HSA-1234174 Cellular response to hypoxia 24/1591 75/10654 1.4747796383414338e-4 4.902345380717882e-4 2.7420525939011585e-4 112399/7321/7422/3091/7323/7316/9978/7322/5715/1387/5698/2033/25994/7428/5702/8453/6233/2056/7311/2034/54583/5696/768/7314 24 Hendra_virus R-HSA-204174 Regulation of pyruvate dehydrogenase (PDH) complex 9/1591 16/10654 1.5244816319158247e-4 5.004687838770809e-4 2.7992962968181396e-4 5160/5165/1737/8050/5467/5162/6256/1738/5164 9 Hendra_virus R-HSA-205043 NRIF signals cell death from the nucleus 9/1591 16/10654 1.5244816319158247e-4 5.004687838770809e-4 2.7992962968181396e-4 8878/23385/7316/4803/7189/6233/7311/5599/7314 9 Hendra_virus R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 9/1591 16/10654 1.5244816319158247e-4 5.004687838770809e-4 2.7992962968181396e-4 55534/3280/84441/10046/8850/1387/2033/9794/3516 9 Hendra_virus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 9/1591 16/10654 1.5244816319158247e-4 5.004687838770809e-4 2.7992962968181396e-4 57154/5590/7316/6233/7048/7311/387/7040/7314 9 Hendra_virus R-HSA-9614657 FOXO-mediated transcription of cell death genes 9/1591 16/10654 1.5244816319158247e-4 5.004687838770809e-4 2.7992962968181396e-4 2308/2309/65018/10018/356/4303/1387/2033/604 9 Hendra_virus R-HSA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 8/1591 13/10654 1.5478396473492871e-4 5.043822299120953e-4 2.8211855641341684e-4 7027/5925/5422/1869/5519/5518/5515/5516 8 Hendra_virus R-HSA-202670 ERKs are inactivated 8/1591 13/10654 1.5478396473492871e-4 5.043822299120953e-4 2.8211855641341684e-4 1849/5594/5528/5519/5518/5595/5515/5516 8 Hendra_virus R-HSA-8847993 ERBB2 Activates PTK6 Signaling 8/1591 13/10654 1.5478396473492871e-4 5.043822299120953e-4 2.8211855641341684e-4 1839/2065/2064/1950/5753/3084/2066/1956 8 Hendra_virus R-HSA-163685 Integration of energy metabolism 31/1591 108/10654 1.697465766582023e-4 5.517806410781367e-4 3.0863013937854967e-4 2788/54331/59345/5578/10681/51764/94235/4082/5528/55970/2778/10768/2792/5519/2793/2785/2783/2784/2782/3630/2786/9370/948/6844/5518/31/2791/2790/5515/2787/5516 31 Hendra_virus R-HSA-114452 Activation of BH3-only proteins 13/1591 30/10654 1.7300278726485333e-4 5.596153729863104e-4 3.130123779364095e-4 596/10018/7027/572/7532/207/10971/7533/1869/10000/7157/208/5599 13 Hendra_virus R-HSA-5654696 Downstream signaling of activated FGFR2 13/1591 30/10654 1.7300278726485333e-4 5.596153729863104e-4 3.130123779364095e-4 5295/4893/6464/5290/5335/8074/10817/2263/2247/2885/3845/3265/5781 13 Hendra_virus R-HSA-1169091 Activation of NF-kappaB in B cells 22/1591 67/10654 1.809944709914773e-4 5.840382563944499e-4 3.266729476431541e-4 8454/1147/8945/4790/6885/5579/5966/6500/8517/7316/5970/4792/8915/5715/23291/5698/5702/6233/7311/3551/5696/7314 22 Hendra_virus R-HSA-389948 PD-1 signaling 11/1591 23/10654 1.8903359748849227e-4 6.084950108936138e-4 3.4035246263134863e-4 5777/5133/3123/919/3122/3113/29126/1445/3932/3127/5781 11 Hendra_virus R-HSA-186712 Regulation of beta-cell development 16/1591 42/10654 1.9873511061965494e-4 6.381712411402998e-4 3.56951412278021e-4 2308/3171/207/55534/3280/6927/84441/10046/8850/1387/10000/2033/3630/208/9794/3516 16 Hendra_virus R-HSA-380108 Chemokine receptors bind chemokines 20/1591 59/10654 2.166348451659318e-4 6.922896138998255e-4 3.872217039197815e-4 729230/7852/6351/1230/2919/6367/6349/3576/2920/6352/6348/3627/6364/4283/6363/2833/6347/6356/1234/6387 20 Hendra_virus R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 20/1591 59/10654 2.166348451659318e-4 6.922896138998255e-4 3.872217039197815e-4 7319/7321/9646/7320/7336/5591/7323/7316/8915/5111/7415/7322/118424/7324/6233/23168/7311/7334/3105/7314 20 Hendra_virus R-HSA-5628897 TP53 Regulates Metabolic Genes 26/1591 86/10654 2.246305855736811e-4 7.161114812385063e-4 4.005461043964434e-4 9377/7532/207/10971/7249/7295/7533/6341/64223/10000/10128/5728/6009/7157/208/2475/51204/6834/4343/1340/1327/4697/5564/2744/57521/7248 26 Hendra_virus R-HSA-5654716 Downstream signaling of activated FGFR4 12/1591 27/10654 2.3012132951122648e-4 7.318522089984438e-4 4.0935044191900866e-4 5295/4893/6464/5290/5335/8074/10817/2247/2885/3845/3265/5781 12 Hendra_virus R-HSA-3232118 SUMOylation of transcription factors 10/1591 20/10654 2.353164481854367e-4 7.465795226602704e-4 4.1758794162403636e-4 1029/51588/3090/10401/7157/7329/7158/9063/4193/8554 10 Hendra_virus R-HSA-1296065 Inwardly rectifying K+ channels 13/1591 31/10654 2.575278960583143e-4 8.1121287258369e-4 4.537396263884586e-4 2788/54331/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 13 Hendra_virus R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 13/1591 31/10654 2.575278960583143e-4 8.1121287258369e-4 4.537396263884586e-4 857/1499/5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 13 Hendra_virus R-HSA-5654687 Downstream signaling of activated FGFR1 13/1591 31/10654 2.575278960583143e-4 8.1121287258369e-4 4.537396263884586e-4 5295/4893/6464/5290/5335/8074/10817/2260/2247/2885/3845/3265/5781 13 Hendra_virus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 15/1591 39/10654 2.767552016565823e-4 8.697081515241291e-4 4.864580741707147e-4 6118/9636/7706/7316/5111/10459/7415/25898/9246/6233/51426/7311/7318/6117/7314 15 Hendra_virus R-HSA-180292 GAB1 signalosome 9/1591 17/10654 2.8110425911212044e-4 8.750610230713773e-4 4.894521217481627e-4 5295/1839/5290/1950/6714/1445/2885/1956/5781 9 Hendra_virus R-HSA-5655862 Translesion synthesis by POLK 9/1591 17/10654 2.8110425911212044e-4 8.750610230713773e-4 4.894521217481627e-4 6118/7316/5111/10459/6233/51426/7311/6117/7314 9 Hendra_virus R-HSA-8934593 Regulation of RUNX1 Expression and Activity 9/1591 17/10654 2.8110425911212044e-4 8.750610230713773e-4 4.894521217481627e-4 894/865/6714/595/861/896/5371/4343/5781 9 Hendra_virus R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 9/1591 17/10654 2.8110425911212044e-4 8.750610230713773e-4 4.894521217481627e-4 2308/857/2309/4303/1027/1026/1647/4088/4087 9 Hendra_virus R-HSA-422356 Regulation of insulin secretion 24/1591 78/10654 2.8828748386894223e-4 8.953153548324192e-4 5.007810752652987e-4 2788/54331/59345/5578/10681/51764/94235/4082/55970/2778/10768/2792/2793/2785/2783/2784/2782/3630/2786/948/6844/2791/2790/2787 24 Hendra_virus R-HSA-449836 Other interleukin signaling 11/1591 24/10654 3.0215044345855227e-4 9.361710461256783e-4 5.23633087024189e-4 1436/1435/1441/1440/836/163702/6844/3716/282618/3588/7297 11 Hendra_virus R-HSA-1236977 Endosomal/Vacuolar pathway 7/1591 11/10654 3.1000226946449003e-4 9.515846925789334e-4 5.322544765747625e-4 3135/3107/3106/4012/3133/3134/3105 7 Hendra_virus R-HSA-5655291 Signaling by FGFR4 in disease 7/1591 11/10654 3.1000226946449003e-4 9.515846925789334e-4 5.322544765747625e-4 5295/4893/5290/5335/2885/3845/3265 7 Hendra_virus R-HSA-8851805 MET activates RAS signaling 7/1591 11/10654 3.1000226946449003e-4 9.515846925789334e-4 5.322544765747625e-4 4893/6464/3082/4233/2885/3845/3265 7 Hendra_virus R-HSA-8875555 MET activates RAP1 and RAC1 7/1591 11/10654 3.1000226946449003e-4 9.515846925789334e-4 5.322544765747625e-4 85440/3082/4233/2885/1398/1399/5879 7 Hendra_virus R-HSA-1250347 SHC1 events in ERBB4 signaling 8/1591 14/10654 3.1388383721522585e-4 9.524502675131738e-4 5.327386227964842e-4 1839/4893/6464/3084/2066/2885/3845/3265 8 Hendra_virus R-HSA-169893 Prolonged ERK activation events 8/1591 14/10654 3.1388383721522585e-4 9.524502675131738e-4 5.327386227964842e-4 5604/5594/5605/4914/4803/1398/1399/5595 8 Hendra_virus R-HSA-180336 SHC1 events in EGFR signaling 8/1591 14/10654 3.1388383721522585e-4 9.524502675131738e-4 5.327386227964842e-4 1839/4893/6464/1950/2885/1956/3845/3265 8 Hendra_virus R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 8/1591 14/10654 3.1388383721522585e-4 9.524502675131738e-4 5.327386227964842e-4 1017/1027/898/1869/890/1026/7157/8900 8 Hendra_virus R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 8/1591 14/10654 3.1388383721522585e-4 9.524502675131738e-4 5.327386227964842e-4 4893/5921/5753/1398/387/3845/3265/5879 8 Hendra_virus R-HSA-75153 Apoptotic execution phase 18/1591 52/10654 3.297449192449694e-4 9.982895381260744e-4 5.583781241219162e-4 2934/2339/1499/5747/10059/841/5339/660/3146/329/999/836/3836/5580/6709/840/7431/5062 18 Hendra_virus R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 20/1591 61/10654 3.5889059963250137e-4 0.0010840462632735143 6.063448486941805e-4 25/5747/4690/4771/5594/4644/919/6850/3320/998/695/2885/1398/7410/10096/3326/7409/60/5879/5595 20 Hendra_virus R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 13/1591 32/10654 3.749514501150144e-4 0.0011299789715311253 6.320366129501381e-4 10694/10575/5203/7203/10576/908/6950/7846/10574/10383/60/22948/10693 13 Hendra_virus R-HSA-8986944 Transcriptional Regulation by MECP2 20/1591 62/10654 4.5652548207033086e-4 0.0013726891199523812 7.677928562091928e-4 818/627/815/8841/5770/5468/817/6657/4233/2289/4988/5728/816/3066/3065/3654/1385/25942/4343/801 20 Hendra_virus R-HSA-2029485 Role of phospholipids in phagocytosis 11/1591 25/10654 4.6724235949602955e-4 0.0013953987395332892 7.804951377586045e-4 5295/5290/5335/5291/5336/919/6850/10768/5580/5296/5581 11 Hendra_virus R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 11/1591 25/10654 4.6724235949602955e-4 0.0013953987395332892 7.804951377586045e-4 10694/10575/7203/10576/908/6950/7846/10574/10383/22948/10693 11 Hendra_virus R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 11/1591 25/10654 4.6724235949602955e-4 0.0013953987395332892 7.804951377586045e-4 1017/902/2305/891/890/5519/8900/7514/5518/5515/5516 11 Hendra_virus R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 9/1591 18/10654 4.879783372829478e-4 0.0014540435590660809 8.13297228804913e-4 7027/891/6790/5111/1647/2033/7157/10498/3276 9 Hendra_virus R-HSA-3899300 SUMOylation of transcription cofactors 16/1591 45/10654 4.960080289749714e-4 0.0014746485895143534 8.2482234031793e-4 6045/51588/1387/10401/1616/2033/7329/4152/10155/10499/9063/25942/648/8648/10891/8554 16 Hendra_virus R-HSA-2871809 FCERI mediated Ca+2 mobilization 13/1591 33/10654 5.349181039111061e-4 0.0015867637925434828 8.875322800318801e-4 6464/5335/5336/6850/10768/4067/695/2885/7410/7006/7409/3702/801 13 Hendra_virus R-HSA-111447 Activation of BAD and translocation to mitochondria 8/1591 15/10654 5.847423983156127e-4 0.0017115358251583086 9.573216255609588e-4 596/572/7532/207/10971/7533/10000/208 8 Hendra_virus R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 8/1591 15/10654 5.847423983156127e-4 0.0017115358251583086 9.573216255609588e-4 6737/29110/7316/22954/3661/6233/7311/7314 8 Hendra_virus R-HSA-354194 GRB2:SOS provides linkage to MAPK signaling for Integrins 8/1591 15/10654 5.847423983156127e-4 0.0017115358251583086 9.573216255609588e-4 5747/3674/6714/2244/2335/2885/2266/2243 8 Hendra_virus R-HSA-372708 p130Cas linkage to MAPK signaling for integrins 8/1591 15/10654 5.847423983156127e-4 0.0017115358251583086 9.573216255609588e-4 5747/3674/6714/2244/2335/1398/2266/2243 8 Hendra_virus R-HSA-6785631 ERBB2 Regulates Cell Motility 8/1591 15/10654 5.847423983156127e-4 0.0017115358251583086 9.573216255609588e-4 1839/2065/2064/1950/3084/2066/387/1956 8 Hendra_virus R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 8/1591 15/10654 5.847423983156127e-4 0.0017115358251583086 9.573216255609588e-4 7316/4233/867/9146/6233/2885/7311/7314 8 Hendra_virus R-HSA-5205685 Pink/Parkin Mediated Mitophagy 10/1591 22/10654 6.189510262925063e-4 0.0017982812542091148 0.0010058413666778118 65018/8878/7416/7316/56993/6233/9804/7311/54543/7314 10 Hendra_virus R-HSA-5655332 Signaling by FGFR3 in disease 10/1591 22/10654 6.189510262925063e-4 0.0017982812542091148 0.0010058413666778118 5295/4893/5290/5335/8074/2261/2247/2885/3845/3265 10 Hendra_virus R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 10/1591 22/10654 6.189510262925063e-4 0.0017982812542091148 0.0010058413666778118 5295/4893/5290/5335/8074/2261/2247/2885/3845/3265 10 Hendra_virus R-HSA-157118 Signaling by NOTCH 54/1591 235/10654 6.198157610879489e-4 0.0017982812542091148 0.0010058413666778118 8454/3725/8841/2208/142678/23509/892/7027/23462/207/55534/3280/6500/409/84441/3091/10013/23385/10046/488/7316/9978/1950/1869/4854/9759/6772/4609/10014/5715/8850/1387/4088/5698/2033/595/55294/5702/3066/3065/7157/83737/861/9794/6233/1385/7311/1956/4343/388585/3516/5696/10959/7314 54 Hendra_virus R-HSA-73894 DNA Repair 72/1591 334/10654 6.300737844438835e-4 0.0018240429252062535 0.001020250766933203 9318/1017/6118/2176/25/2178/4436/902/328/5430/7320/51588/675/5531/4292/9636/545/472/7706/7336/5591/29086/8450/54778/7316/9978/890/6996/64708/5111/10459/7415/7517/10980/10524/5437/10401/1642/10920/25898/2033/142/7398/10987/7157/55215/8900/7329/9246/8924/57599/6233/51426/2873/2968/672/7158/7311/6047/7318/60/8533/5887/6117/5599/7334/10973/50813/7314/51138/8451/8554 72 Hendra_virus R-HSA-170968 Frs2-mediated activation 7/1591 12/10654 6.480770134129146e-4 0.0018679866857195773 0.0010448300434107991 5604/5594/5605/4914/4803/1399/5595 7 Hendra_virus R-HSA-264870 Caspase-mediated cleavage of cytoskeletal proteins 7/1591 12/10654 6.480770134129146e-4 0.0018679866857195773 0.0010448300434107991 2934/841/5339/836/6709/840/7431 7 Hendra_virus R-HSA-111465 Apoptotic cleavage of cellular proteins 14/1591 38/10654 0.00073230521704224295 0.002106173482928016 0.00117805621872013 2934/2339/1499/5747/841/5339/660/329/999/836/5580/6709/840/7431 14 Hendra_virus R-HSA-110320 Translesion Synthesis by POLH 9/1591 19/10654 8.049648196791146e-4 0.0023101268035476547 0.001292134417706171 6118/7316/5111/7415/25898/6233/7311/6117/7314 9 Hendra_virus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 19/1591 60/10654 8.118829765344938e-4 0.0023199161510910047 0.001297609940897463 8454/1017/1027/6500/898/7316/5753/890/1026/5715/6502/5698/595/5702/8900/6233/7311/5696/7314 19 Hendra_virus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 19/1591 60/10654 8.118829765344938e-4 0.0023199161510910047 0.001297609940897463 8454/1147/8945/9039/6500/7316/9020/5970/5715/23291/5698/5702/9040/6233/7311/5971/5696/4791/7314 19 Hendra_virus R-HSA-9020591 Interleukin-12 signaling 16/1591 47/10654 8.593047449484932e-4 0.002450129693032018 0.0013704429122023385 3592/3593/6775/3595/4478/3313/6950/3717/3458/998/3716/3594/302/7297/5062/3586 16 Hendra_virus R-HSA-69620 Cell Cycle Checkpoints 64/1591 293/10654 8.642300599933841e-4 0.002458873912626338 0.0013753338589142024 1017/6118/5905/11065/246184/5525/1029/7321/991/5526/7532/8317/10971/8697/51588/1027/898/7533/545/472/7336/332/8881/29086/5528/7316/4174/891/890/1026/51433/5715/5519/10524/1062/5698/5529/5702/7157/8900/51529/7324/64682/29945/10393/8924/6233/5527/51434/672/7514/7158/7311/5518/6117/29882/7334/51230/5696/7314/996/4193/5515/5516 64 Hendra_virus R-HSA-383280 Nuclear Receptor transcription pathway 17/1591 52/10654 0.0010088517355755894 0.0028641863651641735 0.0016020392367509361 6095/5241/7182/5468/6097/5465/2100/2099/5467/2908/3164/2101/6256/7376/367/7421/10062 17 Hendra_virus R-HSA-110312 Translesion synthesis by REV1 8/1591 16/10654 0.0010170366334396397 0.002868954085374506 0.0016047059887960202 6118/7316/5111/10459/6233/7311/6117/7314 8 Hendra_virus R-HSA-391160 Signal regulatory protein family interactions 8/1591 16/10654 0.0010170366334396397 0.002868954085374506 0.0016047059887960202 5777/5747/653509/6714/140885/2885/2185/5781 8 Hendra_virus R-HSA-8949664 Processing of SMDT1 8/1591 16/10654 0.0010170366334396397 0.002868954085374506 0.0016047059887960202 10730/11331/6687/30968/221154/10367/10939/5245 8 Hendra_virus R-HSA-182971 EGFR downregulation 12/1591 31/10654 0.0010475154924765072 0.002929942910246129 0.0016388191637053179 1839/7316/1950/867/9146/998/6233/2885/7311/1956/10252/7314 12 Hendra_virus R-HSA-399719 Trafficking of AMPA receptors 12/1591 31/10654 0.0010475154924765072 0.002929942910246129 0.0016388191637053179 818/1173/815/5579/817/5578/816/4905/1742/163/10369/4193 12 Hendra_virus R-HSA-399721 Glutamate binding, activation of AMPA receptors and synaptic plasticity 12/1591 31/10654 0.0010475154924765072 0.002929942910246129 0.0016388191637053179 818/1173/815/5579/817/5578/816/4905/1742/163/10369/4193 12 Hendra_virus R-HSA-70268 Pyruvate metabolism 12/1591 31/10654 0.0010475154924765072 0.002929942910246129 0.0016388191637053179 5160/5165/1737/8050/7416/5467/682/5162/6256/3029/1738/5164 12 Hendra_virus R-HSA-1632852 Macroautophagy 26/1591 95/10654 0.0012048280553793344 0.003362842863432193 0.0018809551919424209 65018/8878/7249/1460/10533/64419/7416/192111/7316/8678/6714/64223/56993/6009/55054/6233/2475/9804/7311/54543/55626/3312/5564/57521/7248/7314 26 Hendra_virus R-HSA-1679131 Trafficking and processing of endosomal TLR 7/1591 13/10654 0.001223585570203894 0.0033937184683013664 0.0018982249936077182 54106/10695/7184/7098/51311/81622/51284 7 Hendra_virus R-HSA-179812 GRB2 events in EGFR signaling 7/1591 13/10654 0.001223585570203894 0.0033937184683013664 0.0018982249936077182 1839/4893/1950/2885/1956/3845/3265 7 Hendra_virus R-HSA-879415 Advanced glycosylation endproduct receptor signaling 7/1591 13/10654 0.001223585570203894 0.0033937184683013664 0.0018982249936077182 351/5594/177/3146/6288/6285/5595 7 Hendra_virus R-HSA-5654706 FRS-mediated FGFR3 signaling 9/1591 20/10654 0.0012710407599921237 0.0035179642792250616 0.001967720005008727 4893/8074/10817/2261/2247/2885/3845/3265/5781 9 Hendra_virus R-HSA-2465910 MASTL Facilitates Mitotic Progression 6/1591 10/10654 0.0013418719281519157 0.0036985345019687177 0.002068719222567537 891/5519/5518/84930/5515/5516 6 Hendra_virus R-HSA-8875656 MET receptor recycling 6/1591 10/10654 0.0013418719281519157 0.0036985345019687177 0.002068719222567537 3082/4233/2885/1398/1399/53916 6 Hendra_virus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 16/1591 49/10654 0.001427071165774967 0.003925187426861291 0.0021954941011922565 1017/7027/1027/898/1869/891/890/1026/6790/5111/1647/2033/7157/8900/10498/3276 16 Hendra_virus R-HSA-5656169 Termination of translesion DNA synthesis 12/1591 32/10654 0.0014510539178934038 0.0039828720609397785 0.0022277591270562632 6118/9636/7706/7316/5111/9246/6233/51426/7311/7318/6117/7314 12 Hendra_virus R-HSA-2682334 EPH-Ephrin signaling 25/1591 92/10654 0.0016541150218905801 0.00453083679909159 0.0025342548989627936 1173/5747/1947/23385/4318/5921/6383/4313/10398/6714/4067/2044/2534/998/7525/7410/10096/163/1759/387/60/3265/5062/1969/5879 25 Hendra_virus R-HSA-5656121 Translesion synthesis by POLI 8/1591 17/10654 0.0016711987439529945 0.004553960921927818 0.002547189026626293 6118/7316/5111/10459/6233/7311/6117/7314 8 Hendra_virus R-HSA-9022699 MECP2 regulates neuronal receptors and channels 8/1591 17/10654 0.0016711987439529945 0.004553960921927818 0.002547189026626293 5770/4233/2289/4988/3066/3065/1385/25942 8 Hendra_virus R-HSA-193704 p75 NTR receptor-mediated signalling 26/1591 97/10654 0.001672883603973484 0.004553960921927818 0.002547189026626293 8841/4790/10018/572/8767/8878/23385/4615/7316/5970/4792/836/4803/3066/3065/3654/7189/6233/7410/7409/7311/387/5599/3551/7314/5879 26 Hendra_virus R-HSA-5696400 Dual Incision in GG-NER 14/1591 41/10654 0.0017241947364772432 0.004674404992539739 0.0026145575921990983 6118/8450/7316/9978/5111/1642/142/6233/51426/2968/7311/6117/7314/8451 14 Hendra_virus R-HSA-8875878 MET promotes cell motility 14/1591 41/10654 0.0017241947364772432 0.004674404992539739 0.0026145575921990983 85440/5747/3082/3688/4233/6714/3673/2335/3914/3913/2885/1398/1399/5879 14 Hendra_virus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 18/1591 59/10654 0.0017779883333589577 0.00481038561356626 0.002690616291790652 8454/1147/8945/9039/6500/7316/9020/5715/23291/5698/5702/9040/6233/7311/5971/5696/4791/7314 18 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 296/3952 309/10654 2.530085857710037e-111 3.514289256359241e-108 1.4328275699452632e-108 8454/5689/127544/11065/221687/9666/84937/55070/5682/55819/93611/8916/7321/51665/65264/122769/9021/8697/26235/9817/9039/154881/6478/143471/5705/57674/9690/8452/5709/9978/5695/23304/55236/54620/4734/7337/84676/7704/3093/10489/5711/23327/51465/10616/5683/89910/25898/5699/7328/7428/5702/22954/401036/83737/51529/140461/10075/29945/79176/8924/90135/56658/51434/6468/10425/25793/23295/51666/90293/54461/29882/7334/92591/55182/84961/4591/7332/5696/5691/9820/55658/7314/996/10324/283807/9354/5718/197131/8945/51088/64410/146330/51320/5700/122706/5707/10477/148581/92912/23198/10533/140462/6477/7323/10517/9604/64718/4008/84861/11059/84085/27252/51444/26118/51433/9861/26249/55905/143279/6502/5698/27246/5692/5713/9903/201456/26190/79654/5710/9040/7324/5719/64682/8925/51191/6233/26091/6047/131405/868/136371/127247/5930/11275/29116/26268/115290/51725/140459/23608/55585/64320/51132/899/23352/26224/10293/114088/285231/142678/246184/142686/151636/11146/255488/9616/91694/10193/140739/150726/390594/81559/144699/5706/200845/79876/26263/8881/7326/6049/57630/89890/22888/7317/80196/140456/55958/84078/5714/26272/8651/64219/140458/5688/55336/5687/26270/63893/89122/118424/5708/55008/10422/84727/90933/63891/9246/10393/5704/9870/4012/25847/7327/51343/7311/7318/55175/9320/26232/57520/5694/92369/997/84261/7325/140691/57154/140460/5684/79754/6737/8065/5720/57531/84708/7319/54850/79791/26046/991/84231/10273/7320/5690/223082/5717/25897/9491/6500/26259/10197/53339/154214/7336/64750/51619/23376/54778/142689/7316/10213/114907/54926/7335/222235/25831/7322/5715/9867/5701/23291/5685/5686/55521/55294/135892/8453/80176/8139/126433/26267/142685/5716/90025/84541/23194/55284/80204/26234/27338/23014/90678/5693/5721/51676/57542 296 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-983169 Class I MHC mediated antigen processing & presentation 338/3952 371/10654 2.3469252509174845e-109 1.629939586762193e-106 6.645504131545298e-107 8454/8773/5689/127544/11065/221687/9666/84937/55070/5682/55819/93611/8916/3107/7321/51665/65264/122769/9021/8697/10484/26235/9817/9039/154881/6478/811/143471/5705/57674/10333/9690/8452/5709/9978/5695/23304/567/55236/54620/4734/7337/3693/84676/7704/3106/3093/10489/5711/23327/51465/10616/5683/3309/89910/25898/5699/7328/9632/7428/5702/22954/401036/83737/51529/140461/10075/29945/79176/8924/90135/56658/51434/6468/10425/25793/23295/3133/51666/90293/54461/29882/7334/92591/55182/84961/4591/3551/7332/5696/5691/9820/55658/7314/996/10324/283807/9354/5718/197131/8945/51088/64410/146330/51320/5700/122706/5707/10477/148581/92912/23198/10533/140462/8517/6810/6477/7323/10517/9604/22872/64718/4008/7096/84861/11059/84085/27252/51444/26118/51433/9861/26249/55905/10134/143279/6502/5698/27246/5692/5713/9903/201456/26190/79654/5710/9040/7324/5719/64682/8925/51191/6233/3685/26091/6047/51128/131405/868/136371/6396/127247/1535/5930/11275/29116/26268/115290/51725/140459/23608/55585/64320/51132/899/3135/23352/26224/4688/10293/114088/285231/653361/142678/246184/142686/151636/11146/255488/9616/91694/10802/10193/140739/821/150726/390594/81559/2209/144699/5706/200845/79876/26263/8881/7326/6049/57630/89890/22888/29927/7317/80196/140456/55958/84078/5714/26272/8651/64219/140458/5688/55336/5687/26270/63893/89122/118424/5708/55008/2923/10422/84727/90933/63891/9246/10393/5704/9870/4012/25847/7327/51343/7311/9871/7318/55175/9320/26232/57520/5694/8673/92369/3105/997/84261/7325/140691/57154/1147/140460/5684/79754/6737/8065/5720/57531/84708/7319/54850/79791/26046/991/84231/10273/7320/5690/223082/5717/25897/9491/6500/26259/10197/7099/53339/154214/7336/4615/64750/51619/23376/54778/142689/7316/10213/114907/54926/7335/222235/25831/7322/5715/9867/5701/9341/23291/5685/5686/114609/55521/55294/135892/8453/80176/8139/126433/26267/142685/5716/90025/84541/23194/55284/3134/80204/26234/27338/7097/23014/1536/90678/5693/5721/51676/10427/57542/4360 338 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-449147 Signaling by Interleukins 378/3952 461/10654 4.8976243509585236e-91 2.2676000744937963e-88 9.245340002862056e-89 5295/729230/8454/3605/7124/2308/834/1052/5689/3725/7291/5777/9252/1437/4790/5682/5291/5657/5783/27178/1848/356/3593/246/9021/8878/6624/5908/3082/5743/3091/941/1265/143471/10538/3383/5705/11009/6097/6349/6657/3576/3313/3662/6776/3688/4985/5709/6175/9978/2920/5695/84868/1435/4792/59307/7133/3606/4609/5898/5711/4988/1432/3558/3717/4088/836/5683/2534/2162/5699/3181/5702/4001/3654/3563/2885/85480/8660/282618/6196/3594/1154/50604/6347/5518/1386/6382/9235/7040/3588/6197/4282/7334/3600/3312/1399/3551/55801/3569/5062/5696/5691/51231/4692/7314/3572/3596/5515/257397/3598/5718/54014/10148/8945/5601/1072/3592/5290/3667/6627/5606/90865/64109/9049/11213/3587/7412/5700/122706/5707/27250/8767/29110/1439/5594/4582/23198/23118/6367/4312/9987/8517/6778/7534/6810/332/5528/4313/3565/3934/3976/50615/3185/5970/5443/9261/3718/3627/8807/8809/9861/149233/5519/5598/4208/3567/598/2247/5698/5692/5713/2335/595/6195/5710/3458/10454/7157/5478/5719/6233/7525/6844/2353/604/6809/3932/7076/302/552900/51561/3570/8835/5600/6777/6773/10068/7850/7297/5781/5608/4791/59067/3557/56300/9655/3562/351/6464/3566/6597/5782/6351/7184/3589/6775/50616/3684/3595/821/4318/5706/3726/58480/301/4478/1438/53833/3581/6616/79155/6774/920/6850/1440/5714/6772/8651/7867/5566/64127/8503/1901/3552/2889/5688/79923/5687/4067/3636/5708/5602/29949/57162/5771/998/6648/7189/163702/112744/6654/5704/3716/84639/7311/2939/1270/5293/2185/240/6356/5008/5694/246778/6416/1234/3586/3554/829/5595/3556/5516/6095/1147/5778/596/5055/5684/2208/5720/6885/2309/5604/4215/3561/3578/10392/207/5292/5451/7422/5690/3553/2625/1230/5717/2919/9491/6500/25930/246330/10197/4615/3597/2357/1436/7316/10213/3560/6352/4314/7335/1441/3055/1026/6348/4793/5775/3146/6647/6364/5715/7132/5701/867/466/6950/23291/5685/3320/5686/4843/9466/6288/942/6285/5609/1398/58985/5716/1385/53832/6363/3575/6845/5896/5296/6935/3687/5599/7431/375/3977/3574/3559/3929/3162/1489/57161/1278/4170/5693/3689/5721/3601/5724/5034 378 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-3700989 Transcriptional Regulation by TP53 317/3952 365/10654 2.2104941786009266e-89 7.675941035191718e-87 3.129594389703418e-87 6884/6875/834/5563/3725/9134/4436/83990/64769/9156/57060/1763/7531/1459/79370/7486/6874/10971/9997/133383/9212/5982/27327/7295/7533/2810/55367/1460/11200/472/53632/79813/5431/7001/639/5435/5433/1869/28996/84289/1457/6790/25904/29117/4194/1647/5928/1432/1387/4683/56950/51499/2965/84126/8738/5439/192669/1107/8900/6873/5371/2475/672/55571/6881/2967/51616/5518/1386/55835/10670/4513/4343/6117/11198/7159/57472/904/144455/85456/29883/51497/51230/637/83695/7296/7314/5515/1263/27166/23368/9377/23774/6118/2176/3622/7027/6446/7832/51422/7249/404672/898/117584/27244/7534/332/5438/5934/64065/116028/890/10769/983/1643/8797/9656/5519/27154/5458/83860/57459/2177/10000/5985/2877/900/7994/2068/54541/3066/7157/5984/6233/1025/2353/604/63970/839/10419/5325/50484/5600/9167/6883/6829/79733/26523/7874/317/2744/5608/5884/5810/57521/26155/26013/5875/253260/25920/5170/80010/2963/5434/83667/1820/7862/1029/389541/5457/9219/8445/7532/5436/55240/204851/6878/4869/5931/4850/4292/580/11073/891/80196/54971/4331/5366/641/5111/1108/8148/2966/246175/64223/2962/84883/6119/147923/3364/5571/10524/54457/4848/8812/144715/23019/1616/843/6794/54815/94241/1874/10128/25824/6009/905/1111/2071/55215/8626/208/7311/7161/5562/6880/6908/5983/4697/5564/6882/5565/1020/53615/10397/8795/5432/665/7248/6877/7529/5516/1017/27161/27113/9891/6917/5440/27165/8621/902/5883/25946/9540/5430/10111/8793/207/22974/57690/835/4849/1027/58484/3486/355/6749/545/5441/8794/192670/8550/9337/7316/6872/2539/1026/54205/5933/124446/5395/6879/9150/112858/5876/143686/10848/5437/1350/9099/28984/51755/2033/995/5728/3065/91875/6827/23112/10498/10542/5527/2968/5932/8851/5300/7156/581/1327/3276/5052/138474/133746/1022/8178/10919/4193 317 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5663205 Infectious disease 315/3952 383/10654 3.124463831375974e-76 8.679760523562457e-74 3.538866402695314e-74 3839/6158/6884/23165/6875/5689/6138/2237/6227/7852/6206/6234/6191/6128/5682/6132/6129/6874/6176/1174/811/6224/6146/348995/6154/143471/6202/57122/5705/55048/6169/5431/23511/5435/5709/6175/9978/5433/6218/5695/2960/292/567/6173/23279/5605/6167/5711/23327/23225/5683/2965/6192/2534/6156/5699/6143/5439/5702/6456/6873/3836/6139/30011/2885/163/9972/6881/2967/51616/3921/8021/7040/11198/904/51497/5062/55746/6208/5696/6170/5691/7296/7314/5879/5718/3303/8945/6203/1839/161/5606/6147/25978/5700/122706/5707/2959/8027/6222/2060/8106/23198/404672/84168/9636/10015/5438/6134/10762/6155/1500/4836/9397/6714/6231/9861/79902/6142/9883/23521/83860/51510/999/5698/9146/6455/5692/5713/5710/2068/5902/6207/5478/5719/6233/6844/7514/1025/3932/1213/5610/1211/6188/6396/129401/6883/1175/6829/801/5608/8907/6122/2957/940/805/25920/6230/1173/4928/2963/3838/5434/5903/6857/6194/55706/7175/6166/1938/5436/6136/6878/6125/4869/821/5706/6232/160/6160/6616/293/5611/920/4233/4331/5714/6193/6210/4927/6229/8148/6205/2966/2962/3840/5688/54457/8812/5687/5708/128866/140801/6235/905/6181/2071/5901/8086/5704/3326/7311/6223/25873/93343/6880/6908/7251/5694/3304/1104/2547/9045/6882/2961/6187/6416/5432/6168/22916/1234/6157/6137/6877/5905/6144/3837/6917/5440/5684/9349/8065/4736/5720/902/79872/51121/9631/5604/1499/3159/6159/6217/5430/6152/5690/5045/7520/5717/9491/6500/127833/6749/51065/6141/79023/5441/23636/10197/6164/4686/7316/10213/6872/53371/3055/6209/9688/11224/6165/6130/6879/9150/5715/6204/5701/2958/867/6228/5437/5685/3320/8815/5686/6124/6827/5609/2968/5716/9844/6189/808/6135/6201/375/138474/1022/5693/10254/5721/6457/8178/8480/6133/291 315 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8951664 Neddylation 218/3952 234/10654 5.343396839710556e-75 1.2369963683929938e-72 5.043416666253122e-73 8454/5689/56995/5682/64344/93611/55884/7321/51665/122769/9021/4738/26235/9817/9039/154881/5929/3091/143471/5705/140825/8452/5709/9978/5695/54620/7704/10980/10489/5711/7347/5683/23113/5699/10987/7428/5702/401036/140461/79176/90135/6468/26094/25793/1154/51666/90293/54461/92591/84961/5696/5691/9820/7314/51514/10324/283807/5718/51397/54165/8945/51088/64410/23363/23038/146330/5700/122706/5707/23198/140462/28991/332/7323/9306/10517/4008/84861/84085/27252/1643/26118/9861/122416/26249/6502/90864/55832/5698/5692/10920/5713/9903/201456/26190/10238/5710/9040/5719/10116/6233/83987/136371/8835/127247/11275/54939/26268/115290/54951/51725/140459/55208/10537/8451/899/26224/23412/9655/149951/285231/142686/9616/140739/5931/150726/390594/144699/5706/200845/26263/8450/89890/140456/55958/84078/5714/55527/26272/140458/5688/55336/5687/26270/1161/5708/1642/84727/5704/2873/7311/2034/55175/8533/26232/51667/5694/51122/92369/84261/150684/51138/56929/9318/140460/5684/79754/8065/5720/29099/11091/25879/54850/79791/5690/5717/9491/6500/28952/26259/10197/53339/142689/7316/10213/114907/64708/222235/7322/5715/5701/23291/170622/5685/5686/55294/8453/123879/80176/8139/23142/126433/26043/26267/142685/5716/84541/23194/80204/26234/8883/23014/5693/5721/84259/51676/50813/57542 218 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-68877 Mitotic Prometaphase 187/3952 200/10654 4.736692233032603e-65 9.398950730974692e-63 3.8320908592053245e-63 114791/10844/55839/11130/440145/6249/9735/7531/1459/11190/203068/5526/54801/51807/9212/347688/10274/1460/147841/348995/79441/57122/5116/7278/1780/23122/5048/57405/8655/1457/23279/9702/2491/7846/7840/1060/11064/81027/11004/9184/5518/55835/29922/23332/25909/10726/81930/55746/93323/5515/79682/10403/79861/64151/25936/55869/1454/3619/64105/332/10051/5528/983/79902/3796/79959/5519/81565/80097/91687/10376/23397/10540/85378/83540/7514/54930/54820/113130/6396/1453/27229/64946/9793/140735/220134/84617/4928/5903/11258/22981/55055/8636/80776/1783/401541/7532/55125/10382/79172/121441/7277/9133/79980/6232/23047/9814/653784/5885/23354/891/5501/9738/1639/55722/4957/5566/54821/9183/1062/699/7283/347733/22919/8243/10426/5529/22994/51143/1069/5577/10383/5347/84790/84643/80184/22897/5108/10592/7280/10806/1778/5516/115106/4926/5905/22995/55559/54908/55143/5525/10142/1058/991/79019/348235/80152/1063/8379/95681/23244/23421/55920/79023/10735/112714/1781/80321/4085/55166/10121/84131/3320/79003/9126/9918/10733/4751/5527/27175/80254/701/57551/9662/55142/8481/55755 187 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2555396 Mitotic Metaphase and Anaphase 187/3952 202/10654 3.772652156456664e-63 6.550267306647884e-61 2.6706406054916917e-61 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/57122/5705/7278/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/5520/81027/51529/4001/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/7444/5698/5692/5713/91687/119504/10376/5710/7324/2010/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/26271/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/347733/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/5905/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/7443/112714/1781/7316/10213/4085/55166/5715/5701/5685/8815/5686/79003/9126/9232/5527/9700/5716/701/57551/5693/5721 187 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-68882 Mitotic Anaphase 186/3952 201/10654 9.69642169079384e-63 1.4964810809458496e-60 6.1013741165463004e-61 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/57122/5705/7278/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/5520/81027/51529/4001/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/7444/5698/5692/5713/91687/119504/10376/5710/7324/2010/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/347733/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/5905/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/7443/112714/1781/7316/10213/4085/55166/5715/5701/5685/8815/5686/79003/9126/9232/5527/9700/5716/701/57551/5693/5721 186 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2467813 Separation of Sister Chromatids 178/3952 190/10654 2.643644497866844e-62 3.672022207537046e-60 1.4971376208972234e-60 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/57122/5705/7278/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/81027/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/5698/5692/5713/91687/119504/10376/5710/7324/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/347733/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7280/1778/5516/5905/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/112714/1781/7316/10213/4085/55166/5715/5701/5685/5686/79003/9126/9232/5527/9700/5716/701/57551/5693/5721 178 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69275 G2/M Transition 181/3952 196/10654 1.0782306939400634e-60 1.3615113035297708e-58 5.551082424303868e-59 114791/10844/8454/5689/440145/5682/7531/11190/203068/54801/51807/347688/51400/79441/143471/5705/5116/7278/5048/5709/9978/5695/8655/6790/9702/5711/5928/7846/7840/5683/5699/11064/5702/5520/81027/8900/5518/55835/29922/23332/7465/93323/5696/5691/7314/5515/5718/8945/79861/4659/5700/122706/5707/1454/23198/993/890/983/9861/79959/5519/5698/5692/5713/80097/10376/5710/10540/7157/85378/5719/6233/7514/54930/54820/1453/27229/9793/4218/5500/84617/2305/11258/22981/8636/51512/7532/84962/55125/10382/121441/7277/5706/9133/9814/653784/23354/728642/891/9738/4331/1639/5714/55722/4957/5566/5688/5687/7283/347733/5708/22919/984/10426/22994/79866/1069/5577/5704/3326/7311/10133/10383/5347/84790/80184/5694/22897/5108/7280/10806/1778/5516/115106/1017/22995/55559/5684/994/5720/4605/902/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/112714/1781/7316/10213/80321/1026/10121/5715/84131/5701/23291/5685/3320/5686/2033/995/10733/4751/27175/80254/5716/23194/9662/55142/1022/8481/5693/5721/55755 181 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-453274 Mitotic G2-G2/M phases 182/3952 198/10654 3.340149671212328e-60 3.8662232444282695e-58 1.5763162483440637e-58 114791/10844/8454/5689/440145/5682/7531/11190/203068/54801/51807/347688/51400/79441/143471/5705/5116/7278/5048/5709/9978/1869/5695/8655/6790/9702/5711/5928/7846/7840/5683/5699/11064/5702/5520/81027/8900/5518/55835/29922/23332/7465/93323/5696/5691/7314/5515/5718/8945/79861/4659/5700/122706/5707/1454/23198/993/890/983/9861/79959/5519/5698/5692/5713/80097/10376/5710/10540/7157/85378/5719/6233/7514/54930/54820/1453/27229/9793/4218/5500/84617/2305/11258/22981/8636/51512/7532/84962/55125/10382/121441/7277/5706/9133/9814/653784/23354/728642/891/9738/4331/1639/5714/55722/4957/5566/5688/5687/7283/347733/5708/22919/984/10426/22994/79866/1069/5577/5704/3326/7311/10133/10383/5347/84790/80184/5694/22897/5108/7280/10806/1778/5516/115106/1017/22995/55559/5684/994/5720/4605/902/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/112714/1781/7316/10213/80321/1026/10121/5715/84131/5701/23291/5685/3320/5686/2033/995/10733/4751/27175/80254/5716/23194/9662/55142/1022/8481/5693/5721/55755 182 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5663202 Diseases of signal transduction 288/3952 377/10654 2.0012942778549892e-56 2.1383059630312152e-54 8.718188837943193e-55 5295/8454/2308/27123/5689/374/4893/11052/5335/71/5682/5291/892/5526/817/1452/7039/9530/613/9372/5908/3082/941/143471/23385/2064/5705/54845/5431/6776/5435/5709/9978/5433/5695/9759/9612/5605/4609/4089/22938/5037/3549/5711/1387/3717/4088/2244/5683/324/2534/3690/408/9965/5699/8312/11064/5439/2264/5702/5894/6868/9794/2885/2475/8660/8826/5518/2252/6469/4140/7040/3845/388585/3265/80351/4763/5696/7750/5691/7314/5879/5515/5718/818/5947/8805/1839/26127/5290/3667/79885/2065/2648/9734/55869/5700/3815/122706/5707/51564/7094/8322/55534/5594/3280/2069/8074/7249/23198/84441/7414/10533/10013/23164/2260/5438/5528/83933/102/57085/6714/2099/50846/9861/2248/5519/8850/399687/2932/7046/2247/5698/10000/5692/5713/2335/1445/5710/3066/2280/5719/6233/2266/2246/5154/3932/2931/2243/6777/369/801/5781/5663/940/1523/253260/805/5170/2963/5434/7276/6464/142678/572/5436/4303/409/930/5706/6199/10046/9208/84447/673/6774/2263/4233/8658/1024/5714/6772/6934/64223/10014/2962/8503/5688/5159/5687/29851/5708/5529/816/4087/208/9365/6654/5704/56829/7048/23493/7311/5293/7450/1956/11160/60/9444/2549/5694/4851/5432/22916/11140/7529/5595/5516/4000/1147/27044/815/5440/5684/8841/5720/1487/2309/5604/1499/10018/5525/10142/842/139285/5430/23462/207/5690/5717/1027/9491/6500/5441/10197/2100/2254/4686/7316/10213/1950/9611/1026/10818/7415/5715/10256/2261/5701/867/5437/5685/2255/3164/3320/5686/2033/54894/391/55294/5728/3065/2066/942/5527/5716/1385/5906/5155/4254/5296/808/3516/5693/5721/5245/5156/4193 288 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5633007 Regulation of TP53 Activity 152/3952 160/10654 1.3451791964320267e-55 1.3346099313172036e-53 5.441401561506996e-54 6884/6875/5563/83990/64769/9156/1763/1459/7486/6874/133383/9212/5982/1460/11200/472/53632/79813/639/28996/84289/1457/6790/29117/4194/5928/1432/4683/56950/84126/1107/8900/6873/5371/2475/672/6881/51616/5518/6117/11198/7159/51230/83695/7314/5515/1263/23368/23774/6118/3622/6446/51422/117584/116028/890/983/5519/27154/5458/83860/57459/10000/5985/900/7994/3066/7157/5984/6233/10419/5600/6883/7874/5608/5884/5810/26155/26013/253260/5170/80010/7862/1029/5457/9219/8445/204851/6878/5931/580/11073/80196/54971/641/1108/8148/64223/6119/3364/5571/10524/54457/144715/1616/6794/54815/94241/1111/8626/208/7311/7161/5562/6880/6908/5983/5564/6882/5565/1020/53615/6877/5516/1017/9891/5883/25946/10111/207/22974/6749/545/8550/7316/6872/6879/112858/10848/9099/2033/3065/91875/5527/5932/8851/5300/7156/138474/133746/10919/4193 152 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-68886 M Phase 296/3952 395/10654 7.90022990068243e-55 7.31561288803193e-53 2.982683288819051e-53 114791/10844/23165/5689/55839/11130/11065/440145/6249/5682/9735/7531/1459/11190/7321/203068/5526/54801/51807/8697/5578/9212/347688/10274/5861/5925/1460/147841/348995/79441/143471/57122/5705/5116/7278/1780/23122/23511/5048/5709/5695/57405/8655/1457/23279/9702/5711/2491/10112/7846/23225/7840/5683/1060/5699/11064/5702/5520/81027/51529/4001/29945/11004/51434/9184/9972/5518/55844/55835/29922/8021/29882/23332/25909/10726/81930/55746/93323/5696/5691/7314/996/5515/5718/79682/10403/79861/64151/25936/55869/5700/122706/5707/1454/2801/5594/3619/23198/64105/332/10762/10051/5528/983/51433/9861/79902/3796/8615/79959/5519/9883/81565/7444/5698/5692/5713/80097/91687/119504/10376/23397/5710/10540/85378/7324/2010/83540/5719/64682/6233/7514/54930/54820/113130/9493/6396/129401/1453/27229/64946/9793/140735/220134/84617/4928/26271/5903/55706/7175/11258/22981/246184/55055/8636/80776/1783/401541/7532/55125/10382/79172/121441/7277/5706/9133/79980/25836/6232/23047/8881/9814/653784/5885/23354/891/5501/9738/1639/5714/55722/4957/4927/5566/54821/81876/9183/5688/1062/699/5687/7283/347733/5708/22919/8243/10426/5529/22994/51143/1069/8086/10393/5577/5704/7311/25906/10383/5347/54892/84790/84643/80184/5694/22897/6418/5108/7112/10592/7280/10806/5595/1778/5516/4000/115106/4926/5905/22995/55559/5684/5720/54908/55143/9631/5525/10142/1058/991/79019/5862/348235/80152/5690/1063/8379/95681/5717/9491/140609/23244/23421/55920/79023/23636/10735/10197/7443/112714/1781/7316/10213/80321/53371/26003/4085/9688/55166/10121/5715/84131/5701/5685/3320/8815/5686/79003/9126/9918/10733/4751/9232/5527/9700/27175/80254/5716/701/57551/9662/55142/8481/5693/5721/55755/8480 296 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69620 Cell Cycle Checkpoints 235/3952 293/10654 6.651781488144418e-53 5.774577804395373e-51 2.3543805530405906e-51 5689/55839/11130/9134/83990/11065/6249/5682/9156/57060/9735/1763/7531/7486/7321/5526/10971/8697/9212/5982/7533/2810/147841/348995/11200/143471/472/57122/5705/1780/23122/5048/5709/4174/5695/57405/8655/84515/23279/4194/4998/5711/2491/4683/5683/990/1060/84126/5699/5702/8900/51529/29945/8924/11004/51434/55388/672/9184/5518/6117/29882/7334/23332/7465/25909/51230/10726/81930/55746/5696/83695/5691/7314/996/5515/5718/6118/79682/10403/23594/25936/5700/122706/5707/51588/51720/3619/23198/63967/898/64105/7534/332/5528/993/116028/890/983/51433/9861/79902/3796/9656/5519/81565/5698/5692/5985/5713/91687/119504/5710/7157/5984/7324/83540/5719/64682/6233/7514/7158/54820/6396/64946/9793/5884/5810/140735/220134/4172/80010/4928/5903/8318/246184/55055/51512/1029/80776/1783/401541/7532/79172/4173/5706/9133/79980/6232/580/8881/11073/891/5501/641/5714/54821/6119/9183/3364/10524/5688/1062/699/5687/144715/5708/22919/5529/51143/1111/10393/5704/7311/25906/5347/84643/5983/5694/4176/7529/1778/5516/1017/5905/5684/5720/54908/55143/5883/5525/25946/1058/991/79019/10111/348235/80152/5690/1063/8379/5717/1027/9491/23421/545/55920/79023/10197/7336/1781/7316/10213/4085/1026/4171/55166/5715/7341/5701/5685/5686/995/79003/5527/5716/701/5932/9025/79184/57551/7156/5693/5721/4193 235 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1257604 PIP3 activates AKT signaling 216/3952 264/10654 1.9209253809078292e-51 1.569509031812338e-49 6.399119844757971e-50 5295/1912/2308/5689/374/3725/6591/3643/5682/5291/1822/1459/5526/9112/6045/7039/27327/80012/3082/1460/941/143471/2064/5705/5709/5695/1457/1911/4734/5711/5928/5683/2534/23512/9965/57332/5699/2264/3630/5702/192669/1107/8975/3654/5371/2885/2475/8660/5518/1386/10670/2252/4343/80351/5696/5691/7314/5879/5515/5718/23396/1839/5290/3667/90865/2065/23186/5700/3815/122706/5707/2146/51564/5594/2069/84232/8074/7249/23198/2260/5528/6714/2099/9861/7101/81847/2248/5519/2932/84733/57459/2247/5698/10000/5692/5713/5710/3066/7157/5719/6233/2246/5154/3932/2931/331/8726/8394/26523/7874/5781/57521/23608/940/6015/253260/5170/572/389541/9219/8535/4303/930/5931/5706/6199/2263/4233/8658/5714/1108/2122/64223/10014/8503/5688/5159/5687/29851/5708/54815/6009/5529/7189/208/9365/5704/57504/7311/5293/1956/648/2549/5694/23466/53615/5595/3556/5516/1147/27161/5684/8841/5720/2309/5468/5525/842/5978/8870/10273/207/5690/57690/5717/1027/9491/10197/192670/4615/2100/2254/7316/10213/1950/1026/57167/10818/5715/1958/2261/5701/5685/2255/3164/5686/391/5728/6615/3065/2066/23028/942/5987/23112/10542/5527/5716/1385/5155/4254/5296/5693/5721/5156/4193 216 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9006925 Intracellular signaling by second messengers 240/3952 305/10654 3.4791077160377816e-51 2.684711454209155e-49 1.094596462706624e-49 5295/1912/2308/5689/374/3725/6591/3643/5335/5682/5291/1822/1459/5526/9112/817/6045/5578/7039/5582/27327/80012/3082/1460/941/143471/2064/5705/5709/5695/1457/1911/4734/5711/5928/5683/2534/23512/9965/57332/5699/2264/3630/5702/192669/1107/8975/3654/5371/2885/2475/8660/5518/1386/10670/2252/4343/80351/5696/814/5691/7314/5879/5515/5718/818/23396/1839/5290/3667/90865/2065/23186/5700/3815/122706/5707/5567/2146/51564/5594/2069/84232/8074/7249/23198/2260/5573/5528/6714/2099/9861/7101/81847/2248/5519/2932/84733/57459/2247/5698/10000/5692/5713/5710/3066/7157/5719/6233/5580/2246/5154/3932/2931/3710/331/8726/8394/115/26523/7874/801/5781/57521/23608/940/6015/253260/805/5170/3838/572/389541/9219/8535/4303/5568/930/5931/5706/6199/2263/4233/8658/5714/1108/2122/64223/5566/10014/8503/5688/5159/5687/29851/5708/54815/6009/5529/816/7189/208/9365/5577/5704/57504/7311/5293/1956/648/2549/5694/23466/53615/5595/3556/5516/1147/27161/815/5684/8841/5720/2309/5468/5525/5575/842/5978/8870/10273/207/5690/57690/5717/1027/9491/3708/10197/192670/4615/2100/2254/7316/10213/1950/1026/57167/10818/5715/1958/2261/5701/5576/5685/2255/3164/5686/391/5728/6615/3065/2066/23028/942/5987/23112/10542/5527/5716/1385/5155/4254/5296/5581/808/5693/5721/5156/4193 240 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8856828 Clathrin-mediated endocytosis 137/3952 146/10654 2.5400426220513697e-48 1.8569048431733433e-46 7.570874962125412e-47 5869/374/85439/71/8674/5286/4738/1212/7039/23208/1785/29763/950/8871/10094/554/54874/10980/22848/7037/2017/3482/408/9322/10987/6456/185/8976/30011/2885/163/11037/1759/23149/3312/29993/9185/7314/9856/23396/1839/161/7018/25977/5868/10618/10093/8027/1856/9892/8322/2060/2069/1601/6453/55707/8301/1129/9146/6455/4074/10920/26119/29979/6233/90019/7474/6844/1213/2580/1211/29924/4036/1175/85021/10109/6869/1173/6857/84251/23048/9026/29988/409/112574/160/338/8218/920/22905/26052/8867/10092/9829/2873/10097/7311/1956/60/8533/274/51429/8673/3092/50618/51138/9318/127833/1080/29978/58513/7316/1950/273/64708/10552/26130/3267/3949/867/9341/915/917/6572/115548/5878/10096/143425/3575/6845/551/154/10254/6457/50813/4952/11252 137 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-913531 Interferon Signaling 172/3952 199/10654 7.942362570219616e-48 5.5159708050175236e-46 2.2489426646200812e-46 80263/3839/3443/23165/5777/5335/960/5770/3107/817/9021/348995/3383/57122/11274/55223/3662/3115/23511/567/4734/6672/3113/23279/3106/3459/3717/23225/3117/11074/3836/5371/4599/684/9972/3133/117854/8021/3127/91543/7334/4938/4261/55746/5696/7314/3445/818/115362/7412/85363/9830/163351/9636/2634/3444/10762/2317/115361/3434/10475/3433/79902/23586/9883/3451/10437/3448/1981/10612/3458/3661/7324/3439/51191/6233/5580/81603/10107/5610/3452/4940/6396/3437/129401/6773/7297/5781/3430/3660/3446/8554/3135/3665/3120/4928/3838/5903/10379/55706/7175/3455/2316/2633/4600/3123/23650/2209/8638/25820/1982/7706/23087/9470/3122/3394/3663/6772/8651/4927/3659/3840/2635/3440/5771/3454/816/8086/10346/9246/3716/7311/7318/7726/79097/3456/3105/5595/3460/815/3837/3441/6737/9631/23321/4281/3119/4502/54739/79023/2537/23636/3449/51127/7316/53371/3664/9688/6041/1958/4939/388646/7341/6059/55128/3134/5300/9775/80128/5495/5724/8480 172 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-168254 Influenza Infection 141/3952 155/10654 2.1151788543278043e-45 1.399039727933962e-43 5.704091346508064e-44 3839/6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/23225/6192/6156/6143/5439/3836/6139/9972/3921/8021/7040/55746/6208/6170/3303/6203/6147/6222/8106/9636/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/7514/1213/5610/1211/6188/6396/129401/6122/6230/4928/2963/3838/5434/5903/6194/55706/7175/6166/5436/6136/6125/821/6232/6160/293/5611/6193/6210/4927/6229/6205/2962/3840/140801/6235/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/5440/9349/4736/51121/9631/6159/6217/5430/6152/51065/6141/79023/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/8480/6133 141 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-168255 Influenza Life Cycle 133/3952 144/10654 8.64991487003369e-45 5.4612417065803615e-43 2.226628803865132e-43 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/23225/6192/6156/6143/5439/3836/6139/9972/3921/8021/55746/6208/6170/3303/6203/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/7514/1213/1211/6188/6396/129401/6122/6230/4928/2963/5434/5903/6194/55706/7175/6166/5436/6136/6125/821/6232/6160/5611/6193/6210/4927/6229/6205/2962/140801/6235/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/5440/9349/4736/51121/9631/6159/6217/5430/6152/51065/6141/79023/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/8480/6133 133 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2262752 Cellular responses to stress 322/3952 479/10654 1.3445890827737767e-42 8.120148852055547e-41 3.31070446925534e-41 1912/23165/5689/3725/6782/9134/11065/573/4790/5682/64344/7531/1915/7321/51807/817/6045/8697/9530/347688/27327/80012/7295/5925/3091/348995/143471/472/57122/5705/79813/9681/3576/7278/3313/1780/7001/23511/5709/9978/2114/1869/5695/3305/8655/1911/832/26277/23279/4194/1031/91582/5711/5928/1432/1387/4683/7846/259217/23225/5683/3309/23512/57332/5699/126374/7428/5702/192669/9531/81027/8900/51529/4001/29945/8091/8131/2056/51434/2475/3306/1030/6196/9972/10670/23411/8021/4343/6117/6197/29882/3312/4217/3569/55746/5696/5691/7296/7314/996/5718/818/3303/6118/5601/79861/5606/7027/5700/122706/5707/2146/9114/5594/3308/23198/898/10049/10013/27244/3337/10762/847/7323/890/5970/9261/6667/51433/9861/79902/5598/9883/2932/84733/9973/529/5698/5692/5713/2877/119504/10376/6195/5710/3301/10540/7157/7324/5719/64682/6233/2353/8726/6396/1535/129401/5600/523/26523/528/405/5608/3297/57521/140735/768/6015/84617/4928/4688/1019/5903/83667/55706/7175/653361/5241/11258/9448/246184/112399/1029/1783/389541/25828/8535/84962/10382/5931/10294/7013/7277/1051/1410/50488/5706/8881/6774/1639/5714/4927/7867/64223/6119/3552/10370/10524/5688/5687/57805/3310/2908/347733/5708/5602/7266/25824/6009/51143/816/6648/8086/10393/5704/3326/51343/7311/367/25906/2034/57634/10383/84790/55662/648/5694/3304/23466/3456/2113/6416/10641/7280/10728/829/23523/5595/1778/1017/815/5684/5720/9631/3159/7290/10111/7422/5690/57690/5717/1027/9491/545/79023/23636/10197/192670/10808/112714/3490/8550/29855/1781/7316/10213/10935/53371/1026/9532/54205/9588/9688/10121/7415/6647/8994/7322/5715/5701/5685/3320/5686/2033/1021/6767/25842/8453/50507/23135/10963/22824/23112/5609/10542/5716/9529/5599/54583/5052/1536/5693/5721/55466/2288/5034/8480/10919/51382/4193/2950/23043 322 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-162906 HIV Infection 187/3952 233/10654 2.8441799837887512e-42 1.6460691656177399e-40 6.711266803852405e-41 6884/23165/6875/5689/2237/7852/5682/6874/1174/348995/143471/57122/5705/55048/5431/23511/5435/5709/9978/5433/5695/2960/292/567/23279/5711/23327/23225/5683/2965/2534/5699/5439/5702/6873/3836/163/9972/6881/2967/51616/8021/11198/904/51497/5062/55746/5696/5691/7314/5879/5718/8945/161/25978/5700/122706/5707/2959/23198/404672/10015/5438/10762/4836/9397/9861/79902/9883/83860/51510/5698/5692/5713/5710/2068/5902/5478/5719/6233/7514/1025/3932/6396/129401/6883/1175/6829/8907/2957/940/25920/1173/4928/2963/5434/5903/55706/7175/5436/6878/4869/5706/160/293/920/4331/5714/4927/8148/2966/2962/5688/54457/8812/5687/5708/128866/905/2071/5901/8086/5704/7311/93343/6880/6908/7251/5694/1104/2547/6882/2961/5432/22916/1234/6877/5905/3837/6917/5440/5684/8065/5720/902/9631/3159/5430/5690/5045/7520/5717/9491/6500/6749/79023/5441/23636/10197/4686/7316/10213/6872/53371/3055/9688/6879/9150/5715/5701/2958/5437/5685/8815/5686/6827/2968/5716/9844/375/138474/1022/5693/5721/8178/8480/291 187 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 105/3952 108/10654 1.320748525803054e-41 7.055845009001699e-40 2.876772092639851e-40 5295/3605/7124/2308/1052/7291/356/3593/246/9021/6624/3082/5743/3091/10538/3383/6097/6657/3576/3662/3688/4985/7133/3606/4609/4988/3717/2162/6347/7040/3312/3569/4692/3596/3598/3592/7412/4582/6367/4312/6778/332/4313/3565/3934/3976/5443/3718/149233/598/2247/2335/595/7157/2353/604/7076/51561/3570/7297/9655/3566/7184/3684/4318/3726/58480/301/6774/6772/8651/1901/3552/79923/112744/3716/240/6356/5008/3586/6095/596/2208/2309/3561/207/5292/5451/7422/3553/2625/3597/4314/1026/3320/4843/6288/6935/3687/7431/3929/3162/1278/4170/3689 105 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8957275 Post-translational protein phosphorylation 105/3952 108/10654 1.320748525803054e-41 7.055845009001699e-40 2.876772092639851e-40 56955/4240/3270/9210/10272/2153/7857/29106/91851/6696/51156/1435/265/11098/10130/2200/80341/375056/1114/720/10117/3956/3569/54972/2519/8720/7018/10618/11167/813/5179/8074/51246/348/4924/3484/102/8614/336/6694/4148/174/57104/2335/7466/116519/2266/51280/7076/2243/84141/3488/8542/4221/351/4052/7184/56975/334/3912/338/64856/335/5611/197/3053/3895/5624/1000/54757/8404/255738/3913/652/57719/147111/2719/3487/3371/54587/401138/3486/7425/6383/3827/3490/5589/2621/3915/5768/1471/1462/10232/462/3698/5265/1758/258/11320/5954/213/10970/5034/1356/718 105 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 317/3952 473/10654 1.630495165817629e-41 8.387991797484025e-40 3.4199079891223577e-40 5295/374/5777/627/3643/9252/4893/857/2670/5335/71/5770/5291/1848/10653/5578/7039/1785/5908/3082/51741/23385/2064/1280/1289/54845/5431/8829/6696/6776/5435/3688/5433/5753/5327/7423/4734/10413/5605/3910/5898/1432/3717/55824/2534/3690/9965/5439/2264/5603/3630/6456/83737/6868/4145/30011/2885/2475/8660/163/7073/6196/1759/5518/8440/2252/8874/9564/6197/3845/3265/1399/5062/4486/10252/51231/2323/5829/7314/5879/5515/6387/5607/54106/26999/1839/3918/161/5290/3667/4485/6678/2065/5340/3815/5567/8027/10006/1284/2060/9114/5594/2069/8074/284217/9101/23118/5921/6778/2260/5438/348/5528/9306/1500/3185/11059/102/9261/6714/2099/2248/5519/5598/4208/4670/2567/4909/2247/4914/529/10000/9146/6455/2335/3909/6195/3728/8471/1445/3925/6233/7525/5580/2324/2246/3685/1292/5154/3932/1213/3791/3710/1211/29924/1535/5600/6777/1175/523/6300/528/801/200734/5781/5663/5725/1291/10787/253260/805/25920/5170/4908/1173/4688/2963/5434/5590/6464/85440/653361/5241/2904/6461/5747/5782/7424/135/5436/10019/10193/8483/5568/2322/7074/3315/2241/10451/4318/1277/160/3912/673/6774/2263/4233/6772/8651/26052/7867/64223/5566/5802/2962/1003/8503/5795/2889/10163/5159/4067/5771/1111/998/7058/3481/3913/208/9365/6654/5867/7311/2185/387/1956/60/2549/5058/1020/5432/3480/22916/11140/4916/7529/5595/25759/5516/5440/1282/8065/558/4915/1495/5604/1499/4690/5430/10048/10273/207/7422/10458/5045/3178/3708/5441/58513/2254/4686/7316/1950/9611/9047/57498/3915/10818/1281/3673/2261/867/5437/466/2255/53358/3320/4846/4803/2066/3914/6285/1398/3187/1385/9844/5228/5906/3479/5155/23163/4254/8851/5296/5581/581/808/1536/7057/1278/10254/6457/51382/5156/161742/2887/2242 317 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-168273 Influenza Viral RNA Transcription and Replication 123/3952 134/10654 9.428801472080132e-41 4.67735901597118e-39 1.9070282676613202e-39 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/23225/6192/6156/6143/5439/6139/9972/3921/8021/55746/6208/6170/6203/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/6188/6396/129401/6122/6230/4928/2963/5434/5903/6194/55706/7175/6166/5436/6136/6125/6232/6160/5611/6193/6210/4927/6229/6205/2962/140801/6235/6181/8086/7311/6223/25873/9045/6187/5432/6168/6157/6137/6144/5440/9349/4736/51121/9631/6159/6217/5430/6152/51065/6141/79023/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/8480/6133 123 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6807070 PTEN Regulation 126/3952 140/10654 1.87700498703105e-39 8.990206644779752e-38 3.665439865781143e-38 1912/5689/3725/6591/5682/1822/1459/9112/6045/27327/80012/1460/143471/5705/5709/5695/1457/1911/4734/5711/5928/5683/23512/57332/5699/5702/192669/1107/8975/5371/2475/1386/10670/4343/80351/5696/5691/7314/5718/23186/5700/122706/5707/2146/51564/5594/84232/23198/9861/7101/81847/84733/57459/5698/10000/5692/5713/5710/3066/7157/5719/6233/331/8726/26523/7874/57521/23608/6015/389541/9219/8535/5931/5706/8658/5714/1108/2122/64223/10014/5688/5687/5708/54815/6009/208/5704/57504/7311/648/5694/23466/53615/5595/27161/5684/8841/5720/5468/5978/10273/207/5690/57690/5717/9491/10197/192670/7316/10213/57167/5715/1958/5701/5685/5686/5728/6615/3065/23028/5987/23112/10542/5716/5693/5721 126 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8953897 Cellular responses to external stimuli 323/3952 493/10654 3.3107194173557196e-39 1.532863090235698e-37 6.249708935218868e-38 1912/23165/5689/3725/6782/9134/11065/573/4790/5682/64344/7531/1915/7321/51807/817/6045/8697/9530/347688/27327/80012/7295/5925/3091/348995/143471/472/57122/5705/79813/9681/3576/7278/3313/1780/7001/23511/5709/9978/2114/1869/5695/3305/8655/1911/832/26277/23279/4194/1031/91582/5711/5928/1432/1387/4683/7846/259217/23225/5683/3309/23512/57332/5699/126374/7428/5702/192669/9531/81027/8900/51529/4001/29945/8091/8131/2056/51434/2475/3306/1030/6196/9972/10670/23411/8021/4343/6117/6197/29882/3312/4217/3569/55746/5696/5691/7296/7314/996/5718/818/3303/6118/5601/79861/5606/7027/5700/122706/5707/2146/9114/5594/3308/23198/898/10049/10013/27244/3337/10762/847/7323/890/5970/9261/6667/51433/9861/79902/5598/9883/2932/84733/9973/529/5698/5692/5713/2877/119504/10376/6195/5710/3301/10540/7157/7324/5719/64682/6233/2353/8726/6396/1535/129401/5600/523/26523/528/405/5608/3297/57521/140735/768/6015/84617/4928/4688/1019/5903/83667/55706/7175/653361/5241/11258/9448/246184/112399/1029/1783/389541/25828/8535/84962/10382/5931/10294/7013/7277/1051/1410/50488/5706/8881/6774/1639/5714/4927/7867/64223/6119/3552/10370/10524/5688/5687/57805/3310/2908/347733/5708/5602/7266/25824/6009/51143/816/6648/8086/10393/5704/3326/51343/7311/367/25906/2034/57634/10383/84790/55662/648/5694/3304/23466/3456/2113/6416/10641/7280/10728/829/23523/5595/1778/1017/815/5684/5720/9631/3159/7290/10111/4502/7422/5690/57690/5717/1027/9491/545/79023/23636/10197/192670/10808/112714/3490/8550/29855/1781/7316/10213/10935/53371/1026/9532/54205/9588/9688/10121/7415/6647/8994/7322/5715/5701/5685/3320/5686/2033/1021/6767/25842/8453/50507/23135/10963/22824/23112/5609/10542/5716/9529/5599/54583/5052/1536/5693/5721/55466/2288/5034/8480/10919/51382/4193/2950/23043 323 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 91/3952 92/10654 1.9476881501031162e-38 8.726899485462026e-37 3.558085652819955e-37 6884/6875/5563/83990/9156/1763/1459/7486/6874/9212/5982/1460/11200/472/53632/28996/1457/6790/4194/1432/4683/84126/8900/6873/672/6881/51616/6117/11198/83695/7314/1263/6118/51422/116028/890/83860/5985/7157/5984/6233/5600/6883/5884/5810/26155/80010/8445/204851/6878/580/11073/641/8148/6119/3364/5571/10524/54457/144715/6794/94241/1111/7311/5562/6880/6908/5983/5564/6882/5565/1020/6877/1017/9891/5883/10111/22974/6749/545/8550/7316/6872/6879/112858/5932/8851/5300/7156/138474/4193 91 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 115/3952 125/10654 2.0629991699408608e-38 8.95470577202455e-37 3.650965636276919e-37 56955/4240/3270/9210/10272/2153/7857/29106/91851/6696/51156/1435/265/11098/10130/2200/80341/375056/1114/720/10117/3956/3569/54972/2519/8720/7018/5340/10618/11167/813/5179/8074/4312/51246/348/4924/4313/3484/102/8614/336/6694/5069/4148/174/57104/2335/7466/116519/2266/51280/7076/2243/60676/84141/3488/2147/8542/4221/351/4052/7184/56975/334/3912/338/64856/335/5611/197/3053/3895/5624/1000/54757/3481/8404/255738/3913/354/652/57719/147111/2719/3487/3371/54587/401138/3486/7425/6383/3827/3490/5589/2621/3915/5768/1471/1462/10232/462/3698/5265/1758/3483/258/11320/5954/3479/213/10970/5034/1356/718 115 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5683057 MAPK family signaling cascades 216/3952 294/10654 8.568802693699452e-38 3.606686951984406e-36 1.4704994734323146e-36 2308/5689/374/3725/2674/4893/6711/1437/71/5682/1844/1848/5526/817/7039/27327/5908/3082/143471/2064/5705/8452/5709/9978/5695/2668/5605/4609/5037/5711/3558/3717/2244/5683/2534/3690/408/9965/5699/2264/5702/192669/5894/1847/3563/1739/2885/6709/8660/8826/5518/2252/4140/4343/3845/3265/4763/3569/5062/5696/5691/2323/7314/3572/5879/5515/5718/818/57554/1839/3667/2065/5700/3815/122706/5707/5567/7094/1439/5594/2069/8074/23198/7414/5921/3337/2260/5528/983/3718/6714/9861/2248/5519/3567/2247/5698/5692/5713/2335/1445/5710/8555/896/5719/6233/2266/2246/7514/5154/2243/1843/3570/26523/369/801/200734/7297/5781/11221/805/3562/6464/6712/2904/5747/7010/5568/2322/3315/409/5706/1438/673/2263/4233/5597/84078/5714/5566/6710/5688/5159/5687/5708/5529/816/998/9365/6654/5704/3716/7311/7450/1956/60/5694/5058/7529/5595/25759/5516/27161/815/5684/5720/2309/5604/3561/5525/153090/10642/10048/5690/57690/5717/9491/10197/192670/5596/8550/2254/7316/10213/1950/3560/10818/5715/10256/2261/5701/5685/2255/53358/5686/2066/8556/5979/23112/5527/5716/88/5906/5155/4254/5896/399473/808/3559/8202/5693/5721/5245/5156/161742/284 216 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2500257 Resolution of Sister Chromatid Cohesion 115/3952 126/10654 1.5097260252909798e-37 6.167674850379915e-36 2.5146520173577315e-36 55839/11130/6249/9735/5526/51807/9212/347688/10274/147841/348995/57122/7278/1780/23122/5048/57405/8655/23279/2491/7846/1060/81027/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/79861/25936/55869/3619/64105/332/5528/983/79902/3796/5519/81565/91687/10376/83540/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/55055/80776/1783/401541/10382/79172/7277/9133/79980/6232/23047/5885/891/5501/54821/9183/1062/699/347733/22919/8243/5529/51143/10383/5347/84790/84643/7280/1778/5516/5905/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23244/23421/55920/79023/10735/112714/1781/4085/55166/79003/9126/5527/701/57551 115 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5620912 Anchoring of the basal body to the plasma membrane 95/3952 98/10654 2.3412714468275713e-37 9.291502970409989e-36 3.7882828222352887e-36 79867/7531/11190/203068/54801/85302/79441/5116/5048/22832/8655/9702/132320/7846/7840/11064/84902/5518/55835/23332/93323/1454/54806/91147/983/79959/10540/117177/57545/26005/54930/54820/23322/1453/9793/4218/11258/22981/8636/54903/80776/7532/55125/10382/121441/7277/9814/23354/146057/9738/1639/55722/4957/5566/7283/22919/27077/22994/4867/1069/5577/10383/5347/80184/22897/5108/261734/57787/10806/9657/1778/115106/22995/55559/10142/51134/95681/1781/80321/8766/79598/10121/347240/84131/3320/79600/10733/4751/80254/26123/9662/55142/8481/51259/55755 95 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8878166 Transcriptional regulation by RUNX2 111/3952 121/10654 8.346132671358908e-37 3.220216189032646e-35 1.312929642453536e-35 8454/8493/5689/7291/5682/5925/143471/5705/5709/9978/5695/9759/10413/4089/3549/5711/650/5683/2101/1749/5699/5702/5696/5691/7314/5718/25/6662/5700/122706/5707/5594/3280/23198/10013/2737/865/11059/983/6714/2099/9861/2932/6502/5698/10000/5692/5713/595/5710/5719/6233/7525/133522/4091/117581/1019/3958/5706/1277/891/579/5714/6772/2736/5688/5687/4322/2908/5708/4488/208/5704/23493/7311/367/860/1750/5694/5595/57154/5684/8841/5720/23462/10273/207/5690/5717/9491/6500/4086/59269/10197/7316/10213/4094/1026/5715/5701/5685/5686/55294/861/25925/5716/25937/581/5693/5721/10891 111 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 85/3952 86/10654 7.606830263609431e-36 2.7804966410930262e-34 1.1336494963495497e-34 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 85 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-453276 Regulation of mitotic cell cycle 85/3952 86/10654 7.606830263609431e-36 2.7804966410930262e-34 1.1336494963495497e-34 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 85 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69618 Mitotic Spindle Checkpoint 104/3952 112/10654 8.96012967632785e-36 3.19118464626138e-34 1.3010930542144084e-34 55839/11130/11065/6249/9735/7321/5526/8697/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/996/5515/79682/10403/25936/3619/64105/332/5528/51433/79902/3796/5519/81565/91687/119504/7324/83540/64682/7514/54820/6396/64946/9793/140735/220134/4928/5903/246184/55055/80776/1783/401541/79172/79980/6232/8881/5501/54821/9183/1062/699/22919/5529/51143/10393/25906/5347/84643/1778/5516/5905/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/55166/79003/5527/701/57551 104 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-376176 Signaling by ROBO receptors 169/3952 218/10654 9.97004759010092e-35 3.462099025662545e-33 1.4115488430195517e-33 6158/5689/6138/6227/7852/6206/6234/6191/6128/5682/6132/10298/6129/6176/5578/6224/6146/6154/26986/143471/6202/5705/6169/8829/23122/5709/6175/9978/6218/5695/6173/6167/5711/1605/5683/6192/6156/5699/6143/5702/6139/10487/8440/3921/23332/5062/6208/5696/6170/5691/7314/5879/6387/5718/25/6203/6147/5700/122706/5707/5567/89884/6222/23198/27/2935/6134/6155/6714/6231/9861/6142/23521/5698/5692/5713/1981/5710/6207/5719/6233/6188/6122/6230/6194/6166/56924/6136/5568/6125/5706/6232/6160/5714/6193/6210/6229/6205/5566/5688/5687/5708/140801/6235/6181/998/6654/5704/7311/6223/25873/387/23708/5694/5058/9045/6187/6168/22916/6157/6137/10921/6144/55740/5684/9349/4736/5720/51121/2817/6159/4690/6217/6152/5690/5717/9491/51065/6141/23053/10197/6164/4686/7316/10213/5216/6209/11224/6165/6130/5715/6204/5701/6228/5576/5685/5686/7408/6124/8453/5716/23380/6189/9775/6135/6201/5693/5721/6133 169 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 99/3952 106/10654 1.1097553119373845e-34 3.759634459222017e-33 1.5328584282986211e-33 374/85439/8674/4738/1212/7039/23208/950/554/10980/22848/7037/3482/408/10987/6456/185/30011/2885/163/11037/23149/9185/7314/9856/1839/161/7018/25977/10618/8027/1856/9892/8322/2060/2069/1601/6453/55707/8301/1129/9146/6455/4074/10920/26119/29979/6233/90019/7474/6844/1213/1211/29924/4036/1175/85021/6869/1173/6857/84251/29988/409/160/338/8218/920/22905/2873/7311/1956/8533/8673/50618/51138/9318/127833/1080/29978/58513/7316/1950/64708/3267/3949/867/9341/915/917/6572/115548/143425/3575/6845/551/154/10254/6457/50813 99 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 90/3952 94/10654 4.594969931673212e-34 1.5196221988319263e-32 6.195723867769895e-33 114791/10844/440145/7531/11190/203068/54801/51807/347688/79441/5116/7278/5048/8655/9702/7846/7840/11064/81027/5518/55835/29922/23332/93323/79861/1454/983/79959/80097/10376/10540/85378/54930/54820/1453/27229/9793/84617/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/9738/1639/55722/4957/5566/7283/347733/22919/10426/22994/1069/5577/10383/5347/84790/80184/22897/5108/7280/10806/1778/115106/4926/22995/55559/10142/95681/112714/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 90 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5663220 RHO GTPases Activate Formins 121/3952 140/10654 6.58229166258625e-34 2.1262332835656515e-32 8.668966742892052e-33 55839/11130/71/6249/9735/5526/51807/9212/347688/147841/348995/57122/7278/1780/23122/3688/5048/57405/8655/23279/2491/7846/1060/81027/11004/1855/9184/5518/23332/25909/10726/81930/55746/5879/5515/79682/10403/79861/25936/1856/389/3619/64105/332/5528/6714/79902/3796/5519/81565/91687/10376/23002/83540/1857/7514/54820/6396/64946/9793/140735/220134/84617/4928/114793/5903/55055/80776/1783/401541/10382/79172/7277/79980/6232/5501/54821/9183/1062/699/347733/752/22919/5529/51143/998/10383/5347/387/60/84790/84643/7280/1778/5516/5905/54908/55143/5525/1058/991/79019/348235/80152/1063/6722/8379/23421/55920/79023/112714/1781/4085/5216/81624/55166/79003/5527/701/23380/57551 121 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9010553 Regulation of expression of SLITs and ROBOs 140/3952 171/10654 1.1299991491873755e-33 3.567201859593783e-32 1.4544008188105457e-32 6158/5689/6138/6227/6206/6234/6191/6128/5682/6132/6129/6176/6224/6146/6154/26986/143471/6202/5705/6169/5709/6175/9978/6218/5695/6173/6167/5711/1605/5683/6192/6156/5699/6143/5702/6139/3921/6208/5696/6170/5691/7314/5718/6203/6147/5700/122706/5707/89884/6222/23198/2935/6134/6155/6231/9861/6142/23521/5698/5692/5713/1981/5710/6207/5719/6233/6188/6122/6230/6194/6166/6136/6125/5706/6232/6160/5714/6193/6210/6229/6205/5688/5687/5708/140801/6235/6181/5704/7311/6223/25873/23708/5694/9045/6187/6168/22916/6157/6137/10921/6144/5684/9349/4736/5720/51121/6159/6217/6152/5690/5717/9491/51065/6141/23053/10197/6164/4686/7316/10213/6209/11224/6165/6130/5715/6204/5701/6228/5685/5686/6124/8453/5716/6189/9775/6135/6201/5693/5721/6133 140 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 79/3952 80/10654 2.9392368413473583e-33 9.072444383625513e-32 3.698969405017261e-32 8454/5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 79 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 85/3952 88/10654 3.955412152521629e-33 1.194362495620118e-31 4.8695920779328064e-32 8454/7531/11190/203068/54801/79441/5116/5048/8655/6790/9702/7846/7840/11064/5518/55835/23332/93323/7314/8945/4659/1454/983/79959/10540/6233/54930/54820/1453/9793/4218/5500/11258/22981/8636/7532/84962/55125/10382/121441/7277/9133/9814/23354/891/9738/1639/55722/4957/5566/7283/22919/22994/79866/1069/5577/7311/10133/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/6500/1781/7316/80321/10121/84131/23291/3320/10733/4751/80254/9662/55142/8481/55755 85 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69242 S Phase 133/3952 161/10654 7.71083151971241e-33 2.2787968044426677e-31 9.290990722520218e-32 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/10274/5925/143471/5705/5709/5422/9978/1869/4174/5753/5695/84515/4609/4998/5711/5928/5683/990/5699/5702/8900/51529/29945/51434/6117/29882/10714/7465/5696/5691/7314/996/5718/6118/23594/7027/5700/122706/5707/23198/898/91768/5934/993/890/51433/9861/2932/6502/5698/10000/5692/5985/5713/119504/595/5710/5984/7324/5719/64682/6233/113130/1163/4172/1019/8318/246184/4173/5706/23047/8881/5885/4331/5714/5111/6119/5688/5687/5708/1874/8243/81620/10393/208/5704/51343/7311/25906/51659/5983/5694/4176/1017/5684/994/5720/902/207/5690/5717/1027/9491/6500/23244/10735/10197/4149/7316/10213/1875/1026/4171/5715/5701/5685/5686/9126/5716/5981/1022/5693/5721 133 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5607764 CLEC7A (Dectin-1) signaling 94/3952 101/10654 1.2040488458618479e-32 3.4842163477127223e-31 1.4205664014773558e-31 8454/5689/4790/5682/7321/9039/29108/143471/5705/5530/5709/5695/4792/5711/5683/5699/5702/64170/7334/3551/5696/5691/7314/257397/5718/8945/4773/5700/122706/5707/5336/23198/23118/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/3710/801/4791/805/5170/4772/5706/64581/6850/8915/5714/5688/5687/5708/7189/5704/7311/5971/5694/997/1147/5684/5720/6885/84433/5690/3553/5717/9491/6500/3708/10197/7316/10213/7335/7322/5715/5701/23291/5685/5686/5534/5716/808/5693/5721 94 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 80/3952 82/10654 2.852545604552133e-32 7.924371689445826e-31 3.230883232103259e-31 114791/10844/440145/7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/1454/983/79959/80097/10540/85378/54930/54820/1453/27229/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/728642/9738/1639/55722/4957/5566/7283/22919/984/10426/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 80 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-380287 Centrosome maturation 80/3952 82/10654 2.852545604552133e-32 7.924371689445826e-31 3.230883232103259e-31 114791/10844/440145/7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/1454/983/79959/80097/10540/85378/54930/54820/1453/27229/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/728642/9738/1639/55722/4957/5566/7283/22919/984/10426/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 80 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5357801 Programmed Cell Death 144/3952 181/10654 5.704091576186565e-32 1.5535261175143408e-30 6.333955145486837e-31 5689/2339/5682/7531/55075/356/10971/10059/7533/2810/143471/5705/5709/1869/5695/8655/660/5711/836/5683/324/5699/9414/5702/4001/3836/6709/840/7159/26060/637/5062/5696/5691/7314/578/23368/5718/2934/11035/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/100506658/7082/5339/4836/8797/9861/28988/10134/999/598/5698/10000/5692/708/5713/5710/3002/7157/5719/6233/5580/1613/839/8772/331/8717/317/8743/140735/5747/1029/572/7532/330/118/5706/1829/6774/5366/5714/8428/5688/5687/1832/56616/5708/8837/8626/208/5704/7311/7161/5694/8795/7529/5595/4000/27113/3837/596/5684/5720/7186/51765/1499/10018/842/207/5690/5717/9491/355/10197/7099/7316/10213/54205/3146/5715/5701/329/5685/5686/5534/4137/5716/581/5599/7431/5693/5721/6304/148022 144 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-109581 Apoptosis 142/3952 178/10654 8.834464895008585e-32 2.3598214883013314e-30 9.621340310758337e-31 5689/2339/5682/7531/55075/356/10971/10059/7533/2810/143471/5705/5709/1869/5695/8655/660/5711/836/5683/324/5699/9414/5702/4001/3836/6709/840/7159/26060/637/5062/5696/5691/7314/578/23368/5718/2934/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/100506658/7082/5339/4836/8797/9861/28988/10134/999/598/5698/10000/5692/708/5713/5710/3002/7157/5719/6233/5580/1613/839/8772/331/8717/317/8743/140735/5747/1029/572/7532/118/5706/1829/6774/5366/5714/8428/5688/5687/1832/56616/5708/8837/8626/208/5704/7311/7161/5694/8795/7529/5595/4000/27113/3837/596/5684/5720/7186/51765/1499/10018/842/207/5690/5717/9491/355/10197/7099/7316/10213/54205/3146/5715/5701/329/5685/5686/5534/4137/5716/581/5599/7431/5693/5721/6304/148022 142 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 75/3952 76/10654 1.549467474319416e-31 4.0607741921314505e-30 1.655637539590558e-30 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 75 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-72689 Formation of a pool of free 40S subunits 93/3952 101/10654 2.4713650707749348e-31 6.356900154271082e-30 2.5918019650622124e-30 6158/6138/6227/6206/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/6202/6169/6175/6218/6173/6167/6192/6156/6143/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/8663/23521/6207/6233/51386/6188/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6164/8661/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6133 93 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5684996 MAPK1/MAPK3 signaling 185/3952 255/10654 2.7456764737526302e-31 6.934081130986188e-30 2.8271271634046227e-30 5689/374/2674/4893/6711/1437/71/5682/1844/1848/5526/817/7039/5908/3082/143471/2064/5705/8452/5709/9978/5695/2668/5605/5037/5711/3558/3717/2244/5683/2534/3690/408/9965/5699/2264/5702/5894/1847/3563/1739/2885/6709/8660/8826/5518/2252/4140/3845/3265/4763/3569/5696/5691/2323/7314/3572/5515/5718/818/57554/1839/3667/2065/5700/3815/122706/5707/7094/1439/5594/2069/8074/23198/7414/5921/2260/5528/983/3718/6714/9861/2248/5519/3567/2247/5698/5692/5713/2335/1445/5710/5719/6233/2266/2246/5154/2243/1843/3570/369/801/200734/7297/5781/11221/805/3562/6464/6712/2904/5747/7010/2322/409/5706/1438/673/2263/4233/84078/5714/6710/5688/5159/5687/5708/5529/816/9365/6654/5704/3716/7311/7450/1956/60/5694/7529/5595/25759/5516/815/5684/5720/5604/3561/5525/153090/10048/5690/5717/9491/10197/2254/7316/10213/1950/3560/10818/5715/10256/2261/5701/5685/2255/53358/5686/2066/5979/5527/5716/88/5906/5155/4254/399473/808/3559/5693/5721/5245/5156/161742/284 185 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 74/3952 75/10654 4.171685364481355e-31 1.0347269591543931e-29 4.2187344475394154e-30 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 74 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9607240 FLT3 Signaling 191/3952 267/10654 6.124793156164958e-31 1.4925153848970397e-29 6.085205388765925e-30 5295/5689/374/2674/4893/6711/1437/71/5682/1844/5291/1848/5526/817/7039/5908/3082/143471/2064/5705/8452/6776/5709/9978/5695/2668/5605/5037/5711/3558/3717/2244/5683/2534/3690/408/9965/5699/2264/5702/5894/1847/3563/1739/2885/6709/8660/8826/5518/2252/4140/3845/3265/4763/5696/5691/2323/7314/5515/54106/5718/818/57554/1839/5290/3667/2065/5700/3815/122706/5707/7094/1439/5594/2069/8074/23198/7414/5921/2260/5528/3718/6714/9861/2248/5519/3567/2247/5698/5692/5713/2335/1445/5710/5719/6233/2266/2246/5154/2243/1843/6777/369/801/200734/5781/11221/805/5170/3562/6464/6712/2904/5747/7010/2322/409/5706/1438/673/2263/4233/84078/5714/6710/5688/5159/5687/5708/5529/816/208/9365/6654/5704/3716/7311/7450/1956/60/2549/5694/7529/5595/25759/5516/815/5684/5720/5604/3561/5525/153090/10048/5690/5717/9491/10197/2254/7316/10213/1950/3560/3055/10818/5715/10256/2261/5701/5685/2255/53358/5686/2066/5979/5527/5716/88/5906/5155/4254/5296/399473/808/3559/5693/5721/5245/5156/161742/284 191 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-446652 Interleukin-1 family signaling 118/3952 140/10654 6.642756597144479e-31 1.590825674729945e-29 6.486030942402414e-30 8454/834/5689/5777/4790/5682/5783/27178/8878/143471/5705/5709/9978/5695/4792/59307/3606/5711/4088/5683/5699/5702/3654/7334/3551/5696/5691/7314/3596/257397/5718/8945/90865/11213/5700/122706/5707/8767/29110/23198/23118/8517/3565/5970/8807/8809/9861/5698/5692/5713/5710/10454/5719/6233/10068/7850/5781/5608/4791/3557/56300/351/5782/5706/79155/6774/5714/64127/3552/5688/5687/5708/57162/5771/7189/5704/84639/7311/240/5694/6416/3554/3556/1147/5778/5684/5720/6885/5604/4215/10392/5690/3553/5717/9491/6500/25930/246330/10197/4615/7316/10213/7335/4793/5775/3146/5715/5701/23291/5685/5686/6288/6285/5716/5599/57161/5693/5721 118 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 100/3952 112/10654 7.794796225075165e-31 1.8350799926490514e-29 7.481891827101587e-30 6158/6138/6227/6206/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/6202/6169/6175/6218/6173/6167/6192/6156/6143/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/6233/51386/6188/6122/1968/6230/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6164/8661/9669/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6133 100 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-162909 Host Interactions of HIV factors 111/3952 129/10654 8.052501205718084e-31 1.8641540291237362e-29 7.600430962590052e-30 23165/5689/5682/1174/348995/143471/57122/5705/23511/5709/9978/5695/292/567/23279/5711/23225/5683/2534/5699/5702/3836/163/9972/8021/904/5062/55746/5696/5691/7314/5879/5718/8945/161/5700/122706/5707/23198/10762/9861/79902/9883/5698/5692/5713/5710/5902/5478/5719/6233/7514/1025/3932/6396/129401/1175/8907/940/1173/4928/5903/55706/7175/4869/5706/160/293/920/5714/4927/5688/5687/5708/5901/8086/5704/7311/5694/1104/5905/3837/5684/8065/5720/9631/3159/5690/5717/9491/6500/79023/23636/10197/7316/10213/53371/3055/9688/5715/5701/5685/8815/5686/5716/9844/375/5693/5721/8480/291 111 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8878159 Transcriptional regulation by RUNX3 89/3952 96/10654 1.277767133459007e-30 2.9095386038927225e-29 1.1862618081120721e-29 5689/5682/5705/6097/6696/5709/5695/9759/10413/4609/4089/22938/5711/1387/4088/5683/5699/5702/9794/6932/7040/3845/5696/5691/7314/5718/8463/51176/2648/5700/5707/55534/3280/84441/463/3683/865/83439/6714/9861/8850/5698/5692/5713/595/5710/7157/5719/6233/1029/864/5706/10046/5714/6934/5688/5687/5708/5704/7311/5694/4851/3676/57154/5684/5720/2309/1499/10018/5690/5717/9491/10197/64750/7316/10213/1026/5715/5701/5685/5686/2033/861/5716/25937/3516/5693/5721/4193 89 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9006936 Signaling by TGF-beta family members 93/3952 102/10654 1.788111118015159e-30 4.0059457143920254e-29 1.6332831604281082e-29 10272/892/7321/25805/4738/9372/91851/130399/8239/9612/4609/4089/22938/23327/4088/650/5499/1030/7040/10589/904/7314/5054/7027/11167/6497/51592/50848/7323/91/93/6667/4092/11171/7050/7046/92/94/5494/2280/9958/9040/6233/3625/7514/1025/8928/57530/4091/5500/4090/4221/4093/5590/9765/3726/5501/3624/1024/60436/23645/8812/1874/142/905/4087/7048/7311/387/57154/9241/51377/10273/5045/50855/4086/658/23370/64750/659/54778/7316/1875/9611/5933/867/3065/6498/657/56288/25937/27302/23439 93 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 99/3952 111/10654 1.9057871492778905e-30 4.2018069053126827e-29 1.7131386571620806e-29 6158/6138/6227/6206/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/6192/6156/6143/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/6233/51386/6188/6122/1968/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6164/8661/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6133 99 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-453279 Mitotic G1-G1/S phases 123/3952 149/10654 2.1563030273654645e-30 4.6798514140791096e-29 1.9080444551358882e-29 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/1031/4998/5711/5928/3717/5683/990/5699/5702/5520/8900/55388/1030/5518/6117/7465/5696/5691/7314/5515/6241/5718/6118/25/23594/7027/5700/5707/7153/898/91768/5934/993/890/983/6714/9861/5519/6502/5698/10000/5692/5713/595/5710/896/5719/6233/7298/1719/1163/1859/4172/26271/1019/8318/1029/4173/5706/891/4331/5714/5111/51053/6119/5688/5687/4067/5708/1874/81620/208/5704/7311/5694/4176/5516/1017/894/5684/5720/4605/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5933/4171/5715/5701/5685/5686/1021/3065/5716/1022/5693/5721/7083/1028 123 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-877300 Interferon gamma signaling 86/3952 92/10654 2.4464150913103127e-30 5.227800864353883e-29 2.1314515289472846e-29 80263/5777/960/5770/3107/817/9021/3383/55223/3662/3115/567/6672/3113/3106/3459/3717/3117/11074/5371/3133/117854/3127/4938/4261/818/115362/7412/85363/9830/163351/2634/115361/10475/10437/10612/3458/3661/5580/81603/10107/4940/5781/3660/8554/3135/3665/3120/10379/2633/3123/23650/2209/8638/7706/23087/3122/3394/3663/6772/8651/3659/2635/5771/816/10346/3716/7726/79097/3105/3460/815/6737/23321/4281/3119/4502/51127/3664/4939/388646/7341/55128/3134/80128/5724 86 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72/3952 73/10654 3.020834040308647e-30 6.262594749236881e-29 2.553352260308016e-29 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/5716/701/5693/5721 72 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8939902 Regulation of RUNX2 expression and activity 72/3952 73/10654 3.020834040308647e-30 6.262594749236881e-29 2.553352260308016e-29 8454/5689/7291/5682/143471/5705/5709/9978/5695/5711/650/5683/2101/1749/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/865/11059/2099/9861/2932/6502/5698/5692/5713/5710/5719/6233/133522/5706/579/5714/6772/5688/5687/2908/5708/4488/5704/7311/860/1750/5694/57154/5684/5720/10273/5690/5717/9491/6500/59269/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721/10891 72 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 142/3952 182/10654 7.139072011152543e-30 1.4582604446310121e-28 5.945542944272553e-29 1912/23165/7068/7486/9112/6045/9212/80012/10274/348995/6613/57122/23511/4929/28996/4792/3190/9759/9612/8856/1911/6790/6672/23279/1387/1789/23225/23512/57332/7022/7067/7428/1107/5371/8924/4152/672/115426/9972/10499/6612/5914/8021/6117/11315/55746/7421/4286/10062/7150/6670/3622/1788/51564/51588/3619/7153/51602/2516/8517/332/10762/5465/1655/5970/2099/79902/2494/9656/9883/84733/3066/7157/668/7158/10155/9063/7155/7690/6396/129401/4791/6015/8554/7020/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/5111/4927/10521/1616/2908/8243/142/9971/1069/8086/7329/367/25942/9641/648/6095/5905/1487/55143/9631/5468/7021/3090/79023/23636/10735/3183/53371/6996/9688/7341/10401/2033/9126/3065/6256/5987/7376/6294/8648/6304/8480/10891/7508/4193 142 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 71/3952 72/10654 8.124730557539814e-30 1.5894719358341973e-28 6.480511549231164e-29 5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 71 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 71/3952 72/10654 8.124730557539814e-30 1.5894719358341973e-28 6.480511549231164e-29 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 71 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 71/3952 72/10654 8.124730557539814e-30 1.5894719358341973e-28 6.480511549231164e-29 5689/9134/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/990/5699/5702/8900/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/898/890/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/1017/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 71 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9020702 Interleukin-1 signaling 93/3952 103/10654 1.175780210780488e-29 2.2682759899640247e-28 9.248095809940096e-29 8454/5689/4790/5682/8878/143471/5705/5709/9978/5695/4792/5711/5683/5699/5702/3654/7334/3551/5696/5691/7314/257397/5718/8945/11213/5700/122706/5707/8767/23198/23118/8517/5970/9861/5698/5692/5713/5710/10454/5719/6233/7850/5608/4791/3557/351/5706/79155/5714/64127/3552/5688/5687/5708/57162/7189/5704/7311/5694/6416/3554/3556/1147/5684/5720/6885/5604/4215/10392/5690/3553/5717/9491/6500/246330/10197/4615/7316/10213/7335/4793/3146/5715/5701/23291/5685/5686/6288/6285/5716/57161/5693/5721 93 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69052 Switching of origins to a post-replicative state 84/3952 90/10654 1.595144713805723e-29 3.0351452157207523e-28 1.2374734766077564e-28 8454/5689/9134/11065/5682/7321/8697/143471/5705/5709/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/29882/5696/5691/7314/996/5718/23594/5700/122706/5707/23198/898/890/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/4172/246184/4173/5706/8881/5714/5688/5687/5708/81620/10393/5704/51343/7311/25906/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 84 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5673001 RAF/MAP kinase cascade 179/3952 249/10654 1.7422997094842354e-29 3.2703436438832473e-28 1.3333673452382911e-28 5689/374/2674/4893/6711/1437/71/5682/1844/1848/5526/817/7039/5908/3082/143471/2064/5705/8452/5709/9978/5695/2668/5605/5037/5711/3558/3717/2244/5683/2534/3690/408/9965/5699/2264/5702/5894/1847/3563/1739/2885/6709/8660/8826/5518/2252/4140/3845/3265/4763/5696/5691/2323/7314/5515/5718/818/57554/1839/3667/2065/5700/3815/122706/5707/7094/1439/5594/2069/8074/23198/7414/5921/2260/5528/3718/6714/9861/2248/5519/3567/2247/5698/5692/5713/2335/1445/5710/5719/6233/2266/2246/5154/2243/1843/369/801/200734/11221/805/3562/6464/6712/2904/5747/7010/2322/409/5706/1438/673/2263/4233/84078/5714/6710/5688/5159/5687/5708/5529/816/9365/6654/5704/3716/7311/7450/1956/60/5694/7529/5595/25759/5516/815/5684/5720/5604/3561/5525/153090/10048/5690/5717/9491/10197/2254/7316/10213/1950/3560/10818/5715/10256/2261/5701/5685/2255/53358/5686/2066/5979/5527/5716/88/5906/5155/4254/399473/808/3559/5693/5721/5245/5156/161742/284 179 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-156842 Eukaryotic Translation Elongation 86/3952 93/10654 2.0747878205198276e-29 3.8425070436027205e-28 1.5666468034240945e-28 6158/6138/6227/6206/6234/6191/6128/6132/6129/1915/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6192/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/6122/6230/6194/6166/1938/6136/6125/1937/6232/6160/1933/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/1936/6152/51065/6141/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6133 86 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-141424 Amplification of signal from the kinetochores 88/3952 96/10654 2.4810440505511236e-29 4.475545696383779e-28 1.8247460002686325e-28 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/79902/3796/5519/81565/91687/83540/7514/54820/6396/64946/9793/140735/220134/4928/5903/55055/80776/1783/401541/79172/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/5905/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/55166/79003/5527/701/57551 88 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 88/3952 96/10654 2.4810440505511236e-29 4.475545696383779e-28 1.8247460002686325e-28 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/79902/3796/5519/81565/91687/83540/7514/54820/6396/64946/9793/140735/220134/4928/5903/55055/80776/1783/401541/79172/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/5905/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/55166/79003/5527/701/57551 88 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-156902 Peptide chain elongation 83/3952 89/10654 4.067510937471981e-29 7.243298323267412e-28 2.953199574034988e-28 6158/6138/6227/6206/6234/6191/6128/6132/6129/1915/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6192/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/6122/6230/6194/6166/1938/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6133 83 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 87/3952 95/10654 6.217147696686511e-29 1.0931162216072865e-27 4.456796083700657e-28 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/6173/6167/6192/6156/6143/6139/3921/6208/6170/6203/6147/6222/2935/6134/6155/6231/6142/23521/1981/6207/6233/6188/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/23708/9045/6187/6168/22916/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/4686/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6133 87 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8854518 AURKA Activation by TPX2 71/3952 73/10654 1.8931305691924935e-28 3.286947950760467e-27 1.3401371660862652e-27 7531/11190/203068/54801/79441/5116/5048/8655/6790/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/22974/3161/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 71 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2990846 SUMOylation 143/3952 188/10654 5.377535045281698e-28 9.221476762834912e-27 3.759732104433468e-27 1912/23165/7068/7486/9112/6045/9212/80012/10274/348995/6613/57122/23511/4929/28996/4792/3190/9759/9612/8856/1911/6790/6672/23279/1387/1789/23225/23512/57332/7022/7067/7428/1107/5371/8924/4152/672/115426/9972/10499/6612/5914/8021/6117/11315/55746/7421/4286/10062/7150/6670/3622/1788/51564/51588/3619/7153/51602/2516/8517/332/10762/5465/1655/5970/2099/79902/2494/9656/9883/84733/3066/7157/668/7158/10155/9063/7155/7690/6396/129401/4791/6015/8554/7020/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/5111/4927/10521/1616/2908/8243/142/9971/1069/8086/7329/367/25942/9641/648/6095/5905/29843/1487/55143/9631/5468/7021/3090/79023/23636/10735/3183/53371/6996/9688/7341/10401/2033/9126/3065/6256/5987/7376/6294/8648/6304/8480/10891/7508/4193 143 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-192823 Viral mRNA Translation 82/3952 89/10654 8.409724809885527e-28 1.4245253366989018e-26 5.807999932886281e-27 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6192/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/6122/6230/6194/6166/6136/6125/6232/6160/5611/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6133 82 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 66/3952 67/10654 1.1372944204458175e-27 1.903255361444868e-26 7.759852862395052e-27 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 66 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 79/3952 85/10654 1.703011998998912e-27 2.816051984058915e-26 1.1481459341621738e-26 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/91768/5934/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/1163/1019/5706/4331/5714/5688/5687/5708/1874/208/5704/51343/7311/5694/1017/5684/994/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5715/5701/5685/5686/5716/1022/5693/5721 79 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6807505 RNA polymerase II transcribes snRNA genes 71/3952 74/10654 2.9810847994612833e-27 4.871443278178497e-26 1.9861592843469605e-26 6884/51585/5431/5435/23379/5433/2960/55656/5439/10302/904/65123/55197/2959/79871/5438/6667/29101/79664/25896/23248/1025/7702/6829/2957/2963/5434/26173/5436/26512/6878/55756/58490/2962/51808/8812/129685/905/5452/64859/22936/6621/6880/6908/80237/6619/6882/2961/5432/22916/6618/6877/5440/57508/5430/5451/55174/6617/5441/84524/4686/2958/5437/92105/6827/80789/57117/51593/79035/1022/8178 71 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-380259 Loss of Nlp from mitotic centrosomes 68/3952 70/10654 3.524567664127046e-27 5.627154581002835e-26 2.294273930187963e-26 7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 68 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 68/3952 70/10654 3.524567664127046e-27 5.627154581002835e-26 2.294273930187963e-26 7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 68 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-72613 Eukaryotic Translation Initiation 101/3952 119/10654 4.032299500018695e-27 6.29310562418648e-26 2.5657919940982356e-26 6158/6138/6227/6206/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/6192/6156/6143/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/6233/51386/6188/6122/1968/6230/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6164/8661/9669/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6133 101 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-72737 Cap-dependent Translation Initiation 101/3952 119/10654 4.032299500018695e-27 6.29310562418648e-26 2.5657919940982356e-26 6158/6138/6227/6206/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/6192/6156/6143/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/6233/51386/6188/6122/1968/6230/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6164/8661/9669/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6133 101 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 73/3952 77/10654 5.3413319626001534e-27 8.24345566227957e-26 3.360978474712144e-26 5689/5682/51807/347688/143471/5705/7278/5709/5695/5711/7846/5683/5699/5702/81027/5696/5691/7314/5718/79861/5700/122706/5707/23198/983/9861/5698/5692/5713/10376/5710/7157/5719/6233/84617/51512/10382/7277/5706/9133/891/5714/5688/5687/347733/5708/22919/5704/3326/7311/10383/5347/84790/5694/7280/5684/5720/5690/5717/9491/10197/112714/7316/10213/1026/5715/5701/5685/3320/5686/5716/5693/5721 73 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-72764 Eukaryotic Translation Termination 84/3952 93/10654 6.409569374045873e-27 9.783397648955734e-26 3.988835538735315e-26 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6192/6156/6143/6139/3921/6208/6170/6203/6147/6222/2935/6134/6155/6231/6142/23521/6207/6233/6188/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/23708/9045/6187/6168/6157/6137/6144/9349/4736/327/51121/6159/6217/6152/51065/6141/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6133 84 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-170834 Signaling by TGF-beta Receptor Complex 70/3952 73/10654 7.798724908500182e-27 1.1774379236855166e-25 4.8005881015710505e-26 892/7321/25805/4738/9372/8239/9612/4609/4089/22938/23327/4088/5499/1030/7040/904/7314/5054/7027/6497/51592/50848/7323/6667/4092/11171/7050/7046/5494/2280/9958/9040/6233/7514/1025/57530/5500/4221/5590/3726/5501/1024/60436/23645/8812/1874/142/905/4087/7048/7311/387/57154/51377/10273/5045/50855/23370/64750/54778/7316/1875/9611/5933/867/3065/6498/56288/25937/23439 70 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69206 G1/S Transition 108/3952 131/10654 9.8912830088349e-27 1.4773109784163092e-25 6.02321478070535e-26 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/4998/5711/5928/5683/990/5699/5702/8900/55388/5518/6117/7465/5696/5691/7314/5515/6241/5718/6118/23594/7027/5700/5707/898/91768/5934/993/890/983/9861/5519/6502/5698/10000/5692/5713/595/5710/5719/6233/7298/1719/1163/4172/26271/1019/8318/4173/5706/891/4331/5714/5111/51053/6119/5688/5687/5708/1874/81620/208/5704/7311/5694/4176/5516/1017/5684/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5933/4171/5715/5701/5685/5686/3065/5716/1022/5693/5721/7083 108 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69202 Cyclin E associated events during G1/S transition 77/3952 83/10654 1.0952361622453721e-26 1.6183862014455552e-25 6.59839927534166e-26 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/91768/5934/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/1163/1019/5706/4331/5714/5688/5687/5708/1874/208/5704/7311/5694/1017/5684/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5715/5701/5685/5686/5716/1022/5693/5721 77 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-202424 Downstream TCR signaling 87/3952 98/10654 1.4906936041611928e-26 2.179550964399891e-25 8.886350792672818e-26 5295/8454/5689/4790/5682/5291/7321/143471/5705/3115/5709/5695/4792/3113/5711/3117/5683/5699/5702/3127/7334/3551/5696/5691/7314/5718/8945/5290/5700/122706/5707/8767/23198/23118/8517/5970/9861/5698/5692/5713/5710/5719/6233/3932/3120/5170/3123/5706/3122/920/8915/5714/5688/5687/5708/7189/5704/7311/5694/997/1147/5684/5720/6885/3119/84433/5690/5717/9491/6500/10197/7316/10213/7335/7322/5715/5701/23291/915/5685/917/5686/5728/5716/5296/5693/5721 87 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69615 G1/S DNA Damage Checkpoints 66/3952 68/10654 2.4688398991396776e-26 3.5721027290677213e-25 1.4563989755889768e-25 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/993/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/1111/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 66 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 109/3952 134/10654 5.292492451355976e-26 7.578630943230362e-25 3.089919629766159e-25 5295/8454/5689/3725/4893/5335/4790/5682/5291/7321/143471/5705/5530/5709/5695/4792/5711/5683/2534/5699/5702/2885/3845/7334/3265/3551/5062/5696/5691/7314/5879/257397/5718/8945/5601/4773/5290/5700/122706/5707/5336/5594/4214/23198/23118/8517/5970/9861/5698/5692/5713/5710/10454/5719/6233/2353/3710/801/805/5170/6464/4772/10451/5706/6850/8915/5714/5688/5687/4067/5708/5602/7189/6654/5704/7311/5694/5058/6416/997/5595/1147/5684/5720/6885/84433/5690/5717/9491/6500/3708/10197/7316/10213/7335/7322/5715/5701/23291/5685/5686/5534/5609/5716/5296/808/5599/5693/5721 109 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 62/3952 63/10654 5.885084719695857e-26 8.341206811895453e-25 3.4008330603613016e-25 5689/11065/5682/7321/8697/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/5707/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 62 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69563 p53-Dependent G1 DNA Damage Response 64/3952 66/10654 1.7252329248951427e-25 2.3963485326793535e-24 9.770266458879861e-25 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 64/3952 66/10654 1.7252329248951427e-25 2.3963485326793535e-24 9.770266458879861e-25 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 76/3952 83/10654 2.0989278662533393e-25 2.8865453526988994e-24 1.1768871204213617e-24 8454/5689/4893/4790/5682/143471/5705/5530/5709/5695/4792/5711/5683/5699/5702/4794/3845/3265/3551/5696/5691/7314/5718/8945/4773/5966/5700/122706/5707/23198/8517/5970/9861/5698/5692/5713/5710/2280/5478/5719/6233/801/805/4772/5706/8915/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/84433/5690/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5534/5716/808/5693/5721 76 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5687128 MAPK6/MAPK4 signaling 80/3952 89/10654 2.3577573600756787e-25 3.2107107579854093e-24 1.3090541379986743e-24 2308/5689/3725/5682/27327/143471/5705/5709/5695/4609/5711/5683/5699/5702/192669/4343/5062/5696/5691/7314/5879/5718/5700/122706/5707/5567/23198/3337/983/9861/5698/5692/5713/5710/8555/896/5719/6233/7514/26523/5568/3315/5706/5597/5714/5566/5688/5687/5708/998/5704/7311/5694/5058/27161/5684/5720/2309/10642/5690/57690/5717/9491/10197/192670/5596/8550/7316/10213/5715/5701/5685/5686/8556/23112/5716/5896/8202/5693/5721 80 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5621481 C-type lectin receptors (CLRs) 113/3952 142/10654 2.391177872315393e-25 3.2246078297534767e-24 1.3147201791575693e-24 8454/5689/4586/9252/4893/4790/5682/7321/9039/29108/143471/5705/5530/5709/5695/4792/5711/1387/5683/2534/5699/3385/5702/5894/64170/3845/7334/3265/3551/5062/5696/5691/7314/257397/5718/8945/4773/4589/5700/122706/5707/5567/5336/4582/23198/23118/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/3710/801/4791/805/5170/4772/5568/3384/5706/64581/6850/8915/5714/5566/5688/5687/4067/5708/7189/5704/7311/5971/5694/5058/997/1147/5684/5720/6885/84433/5690/3553/5717/9491/6500/3708/10197/7316/10213/7335/7322/5715/5701/23291/5685/5686/2033/5534/5716/808/5693/5721 113 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69239 Synthesis of DNA 99/3952 119/10654 3.274804151780885e-25 4.373752852715047e-24 1.783243556334126e-24 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/143471/5705/5709/5422/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/6117/29882/10714/5696/5691/7314/996/5718/6118/23594/5700/122706/5707/23198/898/890/51433/9861/6502/5698/5692/5985/5713/119504/5710/5984/7324/5719/64682/6233/4172/8318/246184/4173/5706/8881/5714/5111/6119/5688/5687/5708/81620/10393/5704/51343/7311/25906/51659/5983/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5981/5693/5721 99 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9013694 Signaling by NOTCH4 75/3952 82/10654 5.244599033252043e-25 6.937855292559131e-24 2.828665944751478e-24 8454/5689/5682/23385/5705/5709/9978/5695/22938/5711/1387/4088/5683/5699/4853/5702/9794/388585/5696/5691/7314/5718/2648/5700/5707/55534/3280/84441/7534/102/9861/8850/5698/5692/5713/5710/5719/6233/2324/5663/5706/10460/10046/5714/5688/5687/5708/59/4855/5704/23493/7311/5694/4851/5684/5720/23462/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/2033/55294/5716/3516/5693/5721 75 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 88/3952 102/10654 7.527141974727935e-25 9.863396417827455e-24 4.021452216885431e-24 8454/8792/7124/5689/5682/356/9039/143471/5705/10673/5709/5695/3604/7133/5711/5683/5699/5702/60401/8740/7187/51330/958/5696/5691/939/7314/5718/8945/23495/8744/5700/122706/5707/23198/8764/9020/1896/9861/5698/5692/5713/5710/9040/5719/6233/8742/4791/959/4055/8600/330/5706/5714/5688/5687/5708/5704/7311/5971/115650/5694/1147/4050/5684/5720/7186/5690/5717/9491/6500/10197/7316/10213/5715/7132/5701/329/23291/5685/5686/4049/4982/5716/7293/8784/5693/5721 88 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1234174 Cellular response to hypoxia 70/3952 75/10654 8.820464952135485e-25 1.1450117587398307e-23 4.6683818438257666e-24 5689/5682/64344/7321/3091/143471/5705/5709/9978/5695/5711/1387/5683/5699/126374/7428/5702/2056/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/405/768/112399/84962/5706/5714/10370/5688/5687/5708/5704/7311/2034/55662/5694/5684/5720/7422/5690/5717/9491/10197/7316/10213/8994/7322/5715/5701/5685/5686/2033/8453/5716/54583/5693/5721 70 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 59/3952 60/10654 1.1305851161223164e-24 1.3951944156603713e-23 5.688413441137356e-24 8454/5689/9134/5682/5705/5709/5753/5695/5711/5683/5699/5702/8900/5696/5691/7314/5718/5700/5707/898/890/9861/6502/5698/5692/5713/595/5710/5719/6233/1163/1019/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/5690/5717/1027/9491/6500/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721 59 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 59/3952 60/10654 1.1305851161223164e-24 1.3951944156603713e-23 5.688413441137356e-24 8454/5689/5682/9039/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/5970/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 59 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5610780 Degradation of GLI1 by the proteasome 59/3952 60/10654 1.1305851161223164e-24 1.3951944156603713e-23 5.688413441137356e-24 8454/5689/5682/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/83737/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/8650/9861/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/2735/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5610783 Degradation of GLI2 by the proteasome 59/3952 60/10654 1.1305851161223164e-24 1.3951944156603713e-23 5.688413441137356e-24 8454/5689/5682/1452/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/9861/2932/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/2736/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 59/3952 60/10654 1.1305851161223164e-24 1.3951944156603713e-23 5.688413441137356e-24 8454/5689/5682/1452/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/2737/9861/2932/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-162587 HIV Life Cycle 118/3952 152/10654 1.1350393734314035e-24 1.3951944156603713e-23 5.688413441137356e-24 6884/23165/6875/2237/7852/6874/348995/57122/55048/5431/23511/5435/5433/2960/23279/23327/23225/2965/5439/6873/3836/9972/6881/2967/51616/8021/11198/904/51497/55746/7314/25978/2959/404672/10015/5438/10762/4836/9397/79902/9883/83860/51510/2068/5902/5478/6233/7514/1025/6396/129401/6883/6829/2957/25920/4928/2963/5434/5903/55706/7175/5436/6878/920/4331/4927/8148/2966/2962/54457/8812/128866/905/2071/5901/8086/7311/93343/6880/6908/7251/1104/2547/6882/2961/5432/22916/1234/6877/5905/6917/5440/902/9631/3159/5430/5045/7520/6749/79023/5441/23636/4686/7316/6872/53371/9688/6879/9150/2958/5437/8815/6827/2968/138474/1022/8178/8480 118 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1169091 Activation of NF-kappaB in B cells 64/3952 67/10654 2.46030968694252e-24 2.997693118564176e-23 1.2222037041321108e-23 8454/5689/4790/5682/143471/5705/5709/5695/4792/5711/5683/5699/5702/4794/3551/5696/5691/7314/5718/8945/5966/5700/122706/5707/23198/8517/5970/9861/5698/5692/5713/5710/5719/6233/5706/8915/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/84433/5690/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5716/5693/5721 64 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5676590 NIK-->noncanonical NF-kB signaling 58/3952 59/10654 3.025385352953623e-24 3.65413935239355e-23 1.4898465170609148e-23 8454/5689/5682/9039/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 58 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-3371556 Cellular response to heat stress 79/3952 89/10654 3.2875952791427386e-24 3.9366119333872965e-23 1.6050147551531706e-23 23165/6782/573/7531/1915/817/9530/348995/472/57122/3313/23511/3305/23279/91582/1387/259217/23225/3309/9531/2475/3306/9972/23411/8021/6117/3312/55746/818/3303/6118/5594/3308/10049/10013/3337/10762/9261/79902/9883/2932/6396/129401/3297/57521/4928/5903/55706/7175/1410/4927/64223/6119/57805/3310/7266/816/8086/3326/3304/10728/5595/815/9631/545/79023/23636/10808/53371/9532/9688/7415/3320/2033/6767/22824/9529/2288/8480 79 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-195253 Degradation of beta-catenin by the destruction complex 74/3952 82/10654 8.564050763024923e-24 1.016671411500317e-22 4.1451193163364075e-23 8454/5689/5682/5526/1452/143471/5705/5709/9978/5695/5711/5683/324/5699/8312/5702/6932/5518/5696/5691/7314/5515/5718/51176/8945/5700/122706/5707/23198/5528/83439/9861/5519/2932/5698/5692/5713/5710/5719/6233/5706/5714/6934/5688/5687/5708/5529/7088/5704/7311/5694/5516/5684/5720/1487/1499/5525/139285/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/3065/5527/5716/5693/5721 74 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-927802 Nonsense-Mediated Decay (NMD) 95/3952 115/10654 8.710143842227339e-24 1.016671411500317e-22 4.1451193163364075e-23 6158/9887/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/6173/6167/6192/6156/6143/5520/6139/23381/5518/3921/6208/6170/5515/6203/6147/6222/2935/6134/6155/6231/6142/23521/1981/6207/6233/6188/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/23708/9045/6187/6168/22916/6157/6137/10921/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/4686/6209/11224/6165/6130/6204/6228/55802/6124/6189/9775/6135/6201/6133 95 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 95/3952 115/10654 8.710143842227339e-24 1.016671411500317e-22 4.1451193163364075e-23 6158/9887/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/6173/6167/6192/6156/6143/5520/6139/23381/5518/3921/6208/6170/5515/6203/6147/6222/2935/6134/6155/6231/6142/23521/1981/6207/6233/6188/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/23708/9045/6187/6168/22916/6157/6137/10921/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/4686/6209/11224/6165/6130/6204/6228/55802/6124/6189/9775/6135/6201/6133 95 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-983705 Signaling by the B Cell Receptor (BCR) 93/3952 112/10654 1.2312035489311938e-23 1.4251181078878566e-22 5.810416748464756e-23 5295/8454/5689/5777/4893/4790/5682/143471/5705/5530/5709/5695/4792/5711/5683/2534/5699/5702/30011/2885/4794/3845/3265/3551/933/5696/5691/7314/6786/5718/8945/4773/5966/5700/122706/5707/5336/23198/8517/5970/9861/5698/5692/5713/5710/2280/5478/5719/6233/3710/801/805/4772/930/5706/6850/8915/5714/5688/5687/4067/5708/6654/5704/7311/5293/5694/1147/5684/5720/6885/4690/640/84433/5690/5717/9491/6500/3708/10197/7316/10213/4793/5715/5701/23291/5685/5686/5534/5716/808/5693/5721 93 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69306 DNA Replication 102/3952 127/10654 1.391981117488093e-23 1.59790229106691e-22 6.514883351096948e-23 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/143471/5705/5709/5422/9978/1869/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/55388/6117/29882/10714/5696/5691/7314/996/5718/6118/23594/5700/122706/5707/23198/898/890/51433/9861/6502/5698/5692/5985/5713/119504/5710/5984/7324/5719/64682/6233/4172/8318/246184/4173/5706/8881/5714/5111/51053/6119/5688/5687/5708/81620/10393/5704/51343/7311/25906/51659/5983/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5981/5693/5721 102 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2408557 Selenocysteine synthesis 81/3952 93/10654 1.4717630560980897e-23 1.675638430262497e-22 6.831825057642557e-23 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6192/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6133 81 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-162599 Late Phase of HIV Life Cycle 109/3952 139/10654 1.584532903085424e-23 1.7893627661671983e-22 7.295495950876836e-23 6884/23165/6875/6874/348995/57122/55048/5431/23511/5435/5433/2960/23279/23327/23225/2965/5439/6873/9972/6881/2967/51616/8021/11198/904/51497/55746/7314/25978/2959/404672/10015/5438/10762/4836/9397/79902/9883/83860/51510/2068/5902/5478/6233/7514/1025/6396/129401/6883/6829/2957/25920/4928/2963/5434/5903/55706/7175/5436/6878/4331/4927/8148/2966/2962/54457/8812/128866/905/2071/5901/8086/7311/93343/6880/6908/7251/1104/6882/2961/5432/22916/6877/5905/6917/5440/902/9631/5430/5045/6749/79023/5441/23636/4686/7316/6872/53371/9688/6879/9150/2958/5437/6827/2968/138474/1022/8178/8480 109 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-202403 TCR signaling 97/3952 119/10654 2.0997456235855392e-23 2.352053767064769e-22 9.589670165441597e-23 5295/8454/5689/5335/4790/5682/5291/7321/143471/5705/5788/3115/5709/5695/4792/3113/5711/3117/5683/55824/5699/5702/3127/7334/3551/5062/5696/5691/7314/5718/8945/5290/5700/122706/5707/8767/23198/23118/8517/5970/9861/5698/5692/5713/1445/5710/5719/6233/3932/3120/5170/3123/5706/3122/920/8915/5714/5795/5688/5687/5708/7189/5704/7311/5694/5058/997/1147/55740/5684/5720/6885/4690/3119/84433/5690/5717/9491/6500/10197/7316/10213/7335/7322/5715/5701/23291/915/5685/917/5686/7408/5728/5716/5296/5693/5721 97 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 55/3952 56/10654 5.78147906797268e-23 6.424379540331242e-22 2.6193143061636224e-22 5689/5682/26986/143471/5705/5709/5695/5711/5683/5699/5702/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/9861/5698/5692/5713/1981/5710/5719/6233/3315/5706/5714/5688/5687/5708/5704/7311/5694/3304/5684/5720/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 55 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 81/3952 94/10654 6.793161803363972e-23 7.488652178470283e-22 3.0532339600750355e-22 8454/3725/9252/4790/7321/1848/4792/1432/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/5601/5606/8737/8767/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5608/4791/3665/351/330/7098/79155/7867/64127/5602/7189/7311/9641/6416/5595/5516/1147/6885/5604/10392/6500/7316/7335/4793/3146/7322/329/466/23291/6288/6285/5609/1385/5599/148022 81 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-168898 Toll-like Receptor Cascades 117/3952 155/10654 1.2593455171856555e-22 1.3773471837565948e-21 5.615647643977478e-22 8454/3725/9252/4790/7321/1848/1785/10333/4792/59307/1432/2244/3654/6196/1759/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/54106/11035/8945/5601/5606/11213/8737/8767/5336/29110/5594/4214/23118/841/8517/5528/7323/5970/7096/9261/5519/5598/4208/6195/10454/3661/6233/51311/10010/2266/2353/2243/8772/5600/5781/5608/4791/1508/3665/351/81793/7184/3684/8411/330/7098/338/79155/6279/8651/26052/7867/64127/5602/57162/7189/81622/7311/9641/6416/51284/5595/5516/1147/6885/5604/10392/6500/246330/7099/4615/7100/7316/7335/4793/5775/3146/7322/329/466/23291/114609/6288/6285/5609/1385/5599/7097/3929/57161/3689/148022 117 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 102/3952 129/10654 1.3343453828118142e-22 1.4479732318168828e-21 5.903600460137797e-22 8454/3725/9252/4790/7321/1848/1785/10333/4792/59307/1432/3654/6196/1759/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/5601/5606/11213/8737/8767/5336/29110/5594/4214/23118/841/8517/5528/7323/5970/7096/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/3665/351/3684/330/79155/8651/26052/7867/64127/5602/57162/7189/7311/9641/6416/5595/5516/1147/6885/5604/10392/6500/246330/7099/4615/7316/7335/4793/5775/3146/7322/329/466/23291/114609/6288/6285/5609/1385/5599/7097/3929/57161/3689/148022 102 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 54/3952 55/10654 1.544254881777824e-22 1.6373817028926697e-21 6.675846736813736e-22 8454/5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/26271/5706/5714/5688/5687/5708/5704/51343/7311/5694/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 54 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-4641257 Degradation of AXIN 54/3952 55/10654 1.544254881777824e-22 1.6373817028926697e-21 6.675846736813736e-22 5689/5682/143471/5705/5709/5695/5711/5683/5699/8312/5702/80351/5696/5691/7314/5718/5700/122706/5707/23198/9861/81847/5698/5692/5713/5710/8313/5719/6233/5706/8658/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/5716/5693/5721 54 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8941858 Regulation of RUNX3 expression and activity 54/3952 55/10654 1.544254881777824e-22 1.6373817028926697e-21 6.675846736813736e-22 5689/5682/5705/5709/5695/5711/5683/5699/5702/7040/5696/5691/7314/5718/5700/5707/865/6714/9861/5698/5692/5713/5710/5719/6233/1029/864/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/2033/5716/5693/5721/4193 54 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 62/3952 66/10654 1.7534110180727e-22 1.8450665940174097e-21 7.522608674028014e-22 5689/5682/64344/7321/3091/143471/5705/5709/9978/5695/5711/5683/5699/126374/7428/5702/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/112399/84962/5706/5714/5688/5687/5708/5704/7311/2034/5694/5684/5720/5690/5717/9491/10197/7316/10213/8994/7322/5715/5701/5685/5686/8453/5716/54583/5693/5721 62 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8948751 Regulation of PTEN stability and activity 64/3952 69/10654 2.3535836993661613e-22 2.4579907958042093e-21 1.0021591058638662e-21 5689/5682/1459/1460/143471/5705/5709/5695/1457/4734/5711/5683/5699/5702/8975/80351/5696/5691/7314/5718/5700/122706/5707/23198/9861/81847/5698/10000/5692/5713/5710/5719/6233/331/23608/5706/8658/5714/5688/5687/5708/208/5704/7311/5694/5684/5720/10273/207/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5728/5987/5716/5693/5721 64 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 53/3952 54/10654 4.122759685817249e-22 4.241861632296414e-21 1.729469560210277e-21 8454/5689/5682/143471/5705/5709/9978/5695/6790/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/23194/5693/5721 53 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9604323 Negative regulation of NOTCH4 signaling 53/3952 54/10654 4.122759685817249e-22 4.241861632296414e-21 1.729469560210277e-21 8454/5689/5682/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/5707/7534/9861/5698/5692/5713/5710/5719/6233/5706/10460/5714/5688/5687/5708/4855/5704/7311/5694/5684/5720/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721 53 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-68949 Orc1 removal from chromatin 65/3952 71/10654 7.02994287232611e-22 7.179846065927181e-21 2.9273291527178386e-21 8454/5689/5682/143471/5705/5709/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/5696/5691/7314/5718/23594/5700/122706/5707/23198/890/9861/6502/5698/5692/5713/5710/5719/6233/4172/4173/5706/5714/5688/5687/5708/81620/5704/7311/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 65 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-4641258 Degradation of DVL 55/3952 57/10654 1.0527645894840216e-21 1.0596304455023956e-20 4.3202696349534985e-21 5689/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/1855/5696/5691/7314/5718/5700/122706/5707/1856/23198/59349/9861/5698/5692/5713/5710/5719/6233/1857/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/23072/5693/5721 55 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69541 Stabilization of p53 55/3952 57/10654 1.0527645894840216e-21 1.0596304455023956e-20 4.3202696349534985e-21 5689/5682/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/51230/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721/4193 55 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-166520 Signaling by NTRKs 84/3952 101/10654 1.4687774939431529e-21 1.4677208194870785e-20 5.9841142880834245e-21 5295/627/9252/4893/5335/5291/1848/1785/5605/5898/1432/2534/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5879/5515/5607/161/5290/3667/5594/5528/9261/6714/5519/5598/4208/4909/4914/6195/1213/1211/5600/1175/6300/5781/25920/4908/1173/6464/2904/135/7074/160/673/6774/26052/7867/5802/2889/6654/387/2549/1020/4916/7529/5595/25759/5516/4915/5604/5045/57498/10818/466/53358/4803/1398/1385/5906/8851/5296/581 84 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2871837 FCERI mediated NF-kB activation 72/3952 82/10654 1.5591235220995919e-21 1.5468732658545235e-20 6.306830487891584e-21 8454/5689/4790/5682/7321/143471/5705/5709/5695/4792/5711/5683/5699/5702/7334/3551/5696/5691/7314/257397/5718/8945/5700/122706/5707/23198/23118/8517/5970/9861/5698/5692/5713/5710/10454/5719/6233/5170/5706/8915/5714/5688/5687/4067/5708/7189/5704/7311/5694/997/1147/5684/5720/6885/84433/5690/5717/9491/6500/10197/7316/10213/7335/7322/5715/5701/23291/5685/5686/5716/5693/5721 72 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5688426 Deubiquitination 190/3952 297/10654 1.62786680406517e-21 1.6036219793237738e-20 6.538203363845177e-21 5689/221937/5682/79594/7419/10474/7321/4738/7375/9817/6478/3091/143471/5705/11274/8239/5709/5695/4792/11047/4609/4194/4089/5711/7347/4088/114803/5683/324/408/64135/5699/8312/5702/8900/8975/57599/672/6881/51616/7187/7040/7345/3054/1540/80351/5696/5691/7314/5718/3607/6314/90865/2648/5700/122706/5707/8027/8737/8767/171023/55611/51720/57646/23198/63967/9101/8517/86/993/890/7417/80124/983/4092/2099/1643/9861/23586/81847/8850/7128/7046/6502/5698/9146/5692/5713/5710/10454/219333/7157/9958/8313/5719/6233/9804/55593/10318/23770/8607/7874/5886/23326/51651/93624/8237/4303/409/330/84101/5706/4287/27005/7706/580/7416/79155/25862/9738/8658/84132/5714/79589/55288/27430/64127/5688/9097/5687/5708/4087/63891/84749/7189/5704/7048/7311/367/114548/387/60/5694/7528/9960/23358/5684/8295/5720/10617/7186/56957/6885/991/51377/10392/5690/2625/57506/5717/9491/4086/1080/57695/10197/64750/7316/10213/8314/8678/9100/7415/5715/3416/5701/329/9099/5685/5686/2033/5728/5716/79184/78990/5887/5693/154/10254/5721/4193 190 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-180534 Vpu mediated degradation of CD4 51/3952 52/10654 2.9340813278925486e-21 2.791396550988185e-20 1.1380935504010032e-20 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/920/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 51/3952 52/10654 2.9340813278925486e-21 2.791396550988185e-20 1.1380935504010032e-20 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69610 p53-Independent DNA Damage Response 51/3952 52/10654 2.9340813278925486e-21 2.791396550988185e-20 1.1380935504010032e-20 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 51/3952 52/10654 2.9340813278925486e-21 2.791396550988185e-20 1.1380935504010032e-20 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 51/3952 52/10654 2.9340813278925486e-21 2.791396550988185e-20 1.1380935504010032e-20 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/2932/5698/5692/5713/595/5710/5719/6233/1019/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-167161 HIV Transcription Initiation 47/3952 47/10654 4.810240243070045e-21 4.3956734852791394e-20 1.792180921587039e-20 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-167162 RNA Polymerase II HIV Promoter Escape 47/3952 47/10654 4.810240243070045e-21 4.3956734852791394e-20 1.792180921587039e-20 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-73776 RNA Polymerase II Promoter Escape 47/3952 47/10654 4.810240243070045e-21 4.3956734852791394e-20 1.792180921587039e-20 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 47/3952 47/10654 4.810240243070045e-21 4.3956734852791394e-20 1.792180921587039e-20 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-75953 RNA Polymerase II Transcription Initiation 47/3952 47/10654 4.810240243070045e-21 4.3956734852791394e-20 1.792180921587039e-20 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 47/3952 47/10654 4.810240243070045e-21 4.3956734852791394e-20 1.792180921587039e-20 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-166166 MyD88-independent TLR4 cascade 82/3952 99/10654 7.567089504442009e-21 6.82512163744802e-20 2.782702770601368e-20 8454/3725/9252/4790/7321/1848/4792/1432/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/5601/5606/8737/8767/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/3665/351/330/79155/7867/64127/5602/7189/7311/9641/6416/5595/5516/1147/6885/5604/10392/6500/7099/7316/7335/4793/3146/7322/329/466/23291/6288/6285/5609/1385/5599/148022 82 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 82/3952 99/10654 7.567089504442009e-21 6.82512163744802e-20 2.782702770601368e-20 8454/3725/9252/4790/7321/1848/4792/1432/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/5601/5606/8737/8767/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/3665/351/330/79155/7867/64127/5602/7189/7311/9641/6416/5595/5516/1147/6885/5604/10392/6500/7099/7316/7335/4793/3146/7322/329/466/23291/6288/6285/5609/1385/5599/148022 82 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9614085 FOXO-mediated transcription 60/3952 65/10654 9.516415785697151e-21 8.527936468602156e-20 3.476965495894783e-20 2308/857/2290/65018/57060/2660/356/10971/7295/2810/84676/4089/1647/1387/4088/10628/4801/3630/56729/23411/2538/7534/847/5934/3484/5443/8850/10000/3066/604/5105/7532/4303/23410/4287/4800/901/9314/10370/2908/6794/4852/6648/4087/208/25942/7529/27113/2309/10018/4802/207/1027/6720/1649/114907/1026/2033/3065/10891 60 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 75/3952 88/10654 1.1210613947506707e-20 9.981758187876163e-20 4.06971005651728e-20 5393/5689/5682/5578/26986/143471/5705/5709/5695/5711/1432/5683/5699/5702/11340/8021/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/7534/9261/9861/5698/5692/5713/1981/5710/5719/6233/5580/7514/5600/23016/1994/3315/5706/8125/7538/5714/5688/5687/5708/5704/7311/5694/3304/6418/7529/5684/5720/207/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/55802/5716/54464/5693/54512/5721 75 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 49/3952 50/10654 2.0837532566205678e-20 1.8435243779910628e-19 7.516320831792595e-20 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 49 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 89/3952 112/10654 3.7695738232608675e-20 3.3138848357654083e-19 1.3511197314552612e-19 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6192/6156/6143/6139/3921/6208/6170/6203/6147/6222/6727/6184/6134/6747/6155/6231/6142/23521/6185/6207/6726/6233/6188/6122/6230/6194/6166/1650/6136/6125/6232/6160/6748/29927/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6133 89 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-3371453 Regulation of HSF1-mediated heat shock response 62/3952 69/10654 6.838033477903872e-20 5.973602830697157e-19 2.435525992129946e-19 23165/6782/573/7531/9530/348995/472/57122/3313/23511/3305/23279/91582/259217/23225/3309/9531/3306/9972/23411/8021/6117/3312/55746/3303/6118/5594/3308/10049/3337/10762/9261/79902/9883/2932/6396/129401/3297/4928/5903/55706/7175/4927/6119/57805/3310/7266/8086/3304/5595/9631/545/79023/23636/10808/53371/9532/9688/6767/22824/9529/8480 62 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1236974 ER-Phagosome pathway 71/3952 83/10654 7.84822854751091e-20 6.813243407807909e-19 2.7778598411584673e-19 8773/5689/5682/3107/811/143471/5705/10333/5709/5695/567/3106/5711/5683/5699/5702/3133/3551/5696/5691/7314/5718/5700/122706/5707/23198/8517/6810/7096/9861/5698/5692/5713/5710/5719/6233/3135/5706/29927/5714/5688/5687/5708/2923/5704/7311/5694/8673/3105/1147/5684/5720/5690/5717/9491/10197/7099/4615/7316/10213/5715/5701/9341/5685/5686/114609/5716/3134/7097/5693/5721 71 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-3858494 Beta-catenin independent WNT signaling 108/3952 146/10654 8.093271990634547e-20 6.982332170802103e-19 2.8467998241002855e-19 5689/5682/5331/5578/1212/5582/27327/143471/5705/2775/5530/5709/5695/5711/5683/5699/2782/5702/192669/1855/6932/163/4343/3845/5696/5691/7314/5879/5718/51176/161/51701/5700/122706/5707/1856/8322/23198/10681/7471/83439/9861/5698/5692/5713/2783/23002/5710/5719/6233/7474/1857/1213/3710/1211/1175/26523/801/805/1173/144165/4772/409/5706/160/5714/6934/5688/5687/23236/5708/5704/7311/387/5694/57154/27161/815/5684/5720/6885/1499/59345/5690/57690/5717/9491/50855/3708/10197/192670/64750/7316/10213/5216/5715/5701/5685/5686/5534/23112/23513/5716/808/5693/5721/6259/5592 108 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 69/3952 80/10654 9.89018559346173e-20 8.479918388468113e-19 3.457387816297863e-19 3839/23165/5335/348995/57122/11274/23511/4734/23279/23225/3836/4599/9972/8021/7334/4938/55746/7314/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/51191/6233/5610/4940/6396/129401/4928/3838/5903/55706/7175/2316/4600/8638/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/7318/5595/3837/9631/79023/23636/7316/53371/9688/6041/4939/6059/5300/9775/5495/8480 69 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 101/3952 134/10654 1.266844934024603e-19 1.079538413104401e-18 4.401437355539145e-19 2153/7042/5175/3959/5578/5582/3082/29106/7423/3920/374354/2244/7114/3309/3690/2162/87/10487/7040/54863/350/7043/5054/5099/1072/7018/6678/5340/813/7094/7414/10490/83706/7044/6810/7123/6694/3671/7273/22927/1191/9749/3273/27154/226/2335/1/5478/22915/2266/5154/7076/2243/801/805/351/51097/7424/2316/5552/2157/7277/334/335/308/78991/6403/197/81/3481/5473/8407/7450/29789/10916/139322/5005/7422/5004/5196/3827/1950/2621/5216/5768/710/6647/5265/7078/5345/54676/2/88/1675/3479/5155/51368/808/213/7057/5627 101 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/3952 52/10654 1.3000038201897269e-19 1.1010398208802016e-18 4.489101766765553e-19 5689/5682/143471/472/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-114608 Platelet degranulation 98/3952 129/10654 1.6805705253672547e-19 1.414734824081889e-18 5.768082568724613e-19 2153/7042/5175/3959/3082/29106/7423/3920/374354/2244/7114/3309/3690/2162/87/10487/7040/54863/350/7043/5054/5099/1072/7018/6678/5340/813/7094/7414/10490/83706/7044/7123/6694/3671/7273/22927/1191/9749/3273/27154/226/2335/1/5478/22915/2266/5154/7076/2243/801/805/351/51097/7424/2316/5552/2157/7277/334/335/308/78991/6403/197/81/3481/5473/8407/7450/29789/10916/139322/5005/7422/5004/5196/3827/1950/2621/5216/5768/710/6647/5265/7078/5345/54676/2/88/1675/3479/5155/51368/808/213/7057/5627 98 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-195258 RHO GTPase Effectors 200/3952 327/10654 2.880366707960321e-19 2.4101381670824614e-18 9.826488832483532e-19 55839/11130/64837/71/6249/9735/7531/5526/51807/10971/5578/9212/347688/7533/2810/147841/147179/348995/57122/7278/1780/23122/3688/5048/57405/8655/10094/23279/1432/2017/2491/7846/79784/1060/81027/11004/8976/1855/2885/9184/8826/10499/5518/23332/25909/10726/81930/5062/55746/5879/5515/26999/25/79682/1072/10403/79861/4638/25936/4659/10093/1856/10006/4771/389/5594/3619/64105/7534/332/5528/6714/79902/3796/5519/81565/999/91687/10376/23002/83540/5580/1857/128239/9055/7514/54820/6396/1535/5600/801/64946/9793/10109/5586/140735/5500/10787/4221/805/220134/5170/84617/4928/4688/5590/114793/5903/653361/55055/5747/80776/1783/401541/2316/7532/10382/10627/79172/7277/79980/6232/5501/6279/54821/10092/9183/10163/1062/699/347733/752/22919/3895/5529/51143/998/10788/354/10097/367/10383/5347/387/60/84790/84643/5058/7280/4629/7529/5595/1778/5516/5905/54908/55143/1495/1499/5525/4690/1058/991/79019/4627/348235/80152/10458/1063/6722/8379/1027/1080/23421/55920/79023/112714/1781/10398/4085/5216/10552/81624/55166/4637/995/79003/391/23028/5527/10096/701/23380/9928/3799/57551/5300/808/10095/1536 200 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 49/3952 51/10654 3.397365353305896e-19 2.8257128597256823e-18 1.1520848156814196e-18 5689/5682/143471/5705/5709/5695/5711/4946/5683/5699/5702/5696/5691/5718/1728/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/5706/4947/5714/5688/5687/5708/4953/5704/5694/5684/5720/5690/51686/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 49 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69481 G2/M Checkpoints 119/3952 168/10654 3.887002074148333e-19 3.213717786304782e-18 1.3102801478018817e-18 5689/83990/5682/9156/1763/7531/7486/10971/5982/7533/2810/11200/143471/472/5705/5709/4174/5695/84515/4998/5711/4683/5683/990/84126/5699/5702/8924/55388/672/6117/7334/7465/5696/83695/5691/7314/5718/6118/23594/5700/122706/5707/51588/51720/23198/63967/7534/993/116028/983/9861/9656/5698/5692/5985/5713/5710/7157/5984/5719/6233/7158/5884/5810/4172/80010/8318/51512/7532/4173/5706/9133/580/11073/891/641/5714/6119/3364/10524/5688/5687/144715/5708/1111/5704/7311/5983/5694/4176/7529/1017/5684/5720/5883/10111/5690/5717/9491/545/10197/7336/7316/10213/4171/5715/7341/5701/5685/5686/995/5716/5932/9025/79184/7156/5693/5721 119 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1236975 Antigen processing-Cross presentation 80/3952 99/10654 4.467550925773412e-19 3.671851027159331e-18 1.497067828132106e-18 8773/5689/5682/3107/811/143471/5705/10333/5709/5695/567/3693/3106/5711/5683/5699/5702/3133/3551/5696/5691/7314/5718/5700/122706/5707/23198/8517/6810/7096/9861/5698/5692/5713/5710/5719/6233/3685/1535/3135/4688/653361/2209/5706/29927/5714/5688/5687/5708/2923/5704/4012/7311/5694/8673/3105/1147/5684/5720/5690/5717/9491/10197/7099/4615/7316/10213/5715/5701/9341/5685/5686/114609/5716/3134/7097/1536/5693/5721/4360 80 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-187037 Signaling by NTRK1 (TRKA) 68/3952 80/10654 9.90162920232935e-19 8.090213507079687e-18 3.2984993875251956e-18 5295/9252/4893/5335/5291/1848/1785/5605/5898/1432/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5515/5607/161/5290/3667/5594/5528/9261/6714/5519/5598/4208/4914/6195/1213/1211/5600/1175/6300/1173/6464/135/160/673/6774/26052/7867/2889/6654/387/7529/5595/25759/5516/4915/5604/57498/10818/466/53358/4803/1398/1385/5906/5296 68 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 71/3952 85/10654 1.2552104397789977e-18 1.0077961276607097e-17 4.108933474907824e-18 8454/3725/9252/4790/1848/4792/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/5601/5606/8767/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/81793/79155/7867/64127/5602/57162/7189/7311/6416/5595/5516/1147/6885/5604/10392/6500/246330/4615/7100/7316/7335/4793/3146/466/23291/6288/6285/5609/1385/5599/57161 71 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 71/3952 85/10654 1.2552104397789977e-18 1.0077961276607097e-17 4.108933474907824e-18 8454/3725/9252/4790/1848/4792/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/5601/5606/8767/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/81793/79155/7867/64127/5602/57162/7189/7311/6416/5595/5516/1147/6885/5604/10392/6500/246330/4615/7100/7316/7335/4793/3146/466/23291/6288/6285/5609/1385/5599/57161 71 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-975871 MyD88 cascade initiated on plasma membrane 71/3952 85/10654 1.2552104397789977e-18 1.0077961276607097e-17 4.108933474907824e-18 8454/3725/9252/4790/1848/4792/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/5601/5606/8767/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/81793/79155/7867/64127/5602/57162/7189/7311/6416/5595/5516/1147/6885/5604/10392/6500/246330/4615/7100/7316/7335/4793/3146/466/23291/6288/6285/5609/1385/5599/57161 71 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 77/3952 95/10654 1.4770255947686554e-18 1.1723363149335213e-17 4.779788090138567e-18 8454/3725/9252/4790/1848/10333/4792/59307/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/5601/5606/11213/8767/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/79155/8651/7867/64127/5602/57162/7189/7311/6416/5595/5516/1147/6885/5604/10392/6500/246330/7099/4615/7316/7335/4793/3146/466/23291/114609/6288/6285/5609/1385/5599/7097/57161 77 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 77/3952 95/10654 1.4770255947686554e-18 1.1723363149335213e-17 4.779788090138567e-18 8454/3725/9252/4790/1848/10333/4792/59307/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/5601/5606/11213/8767/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/79155/8651/7867/64127/5602/57162/7189/7311/6416/5595/5516/1147/6885/5604/10392/6500/246330/7099/4615/7316/7335/4793/3146/466/23291/114609/6288/6285/5609/1385/5599/7097/57161 77 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-4086400 PCP/CE pathway 75/3952 92/10654 2.186492300573525e-18 1.725589662213992e-17 7.035483598735387e-18 5689/5682/5578/1212/5582/143471/5705/5709/5695/5711/5683/5699/5702/1855/163/5696/5691/7314/5879/5718/161/5700/122706/5707/1856/8322/23198/7471/9861/5698/5692/5713/23002/5710/5719/6233/7474/1857/1213/1211/1175/1173/144165/409/5706/160/5714/5688/5687/5708/5704/7311/387/5694/57154/5684/5720/5690/5717/9491/50855/10197/64750/7316/10213/5216/5715/5701/5685/5686/23513/5716/5693/5721/6259 75 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5658442 Regulation of RAS by GAPs 60/3952 68/10654 2.21992395880259e-18 1.7322889768408974e-17 7.062797692701322e-18 5689/4893/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/3845/3265/4763/5696/5691/7314/5718/5700/122706/5707/23198/5921/9861/5698/5692/5713/5710/5719/6233/200734/5706/84078/5714/5688/5687/5708/5704/7311/5694/5684/5720/153090/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/399473/5693/5721/161742 60 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-68867 Assembly of the pre-replicative complex 60/3952 68/10654 2.21992395880259e-18 1.7322889768408974e-17 7.062797692701322e-18 5689/5682/143471/5705/5709/1869/4174/5695/84515/4998/5711/5683/990/5699/5702/5696/5691/7314/5718/23594/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/4172/4173/5706/5714/51053/5688/5687/5708/81620/5704/7311/5694/4176/5684/5720/5690/5717/9491/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 60 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 47/3952 49/10654 2.3137451086735775e-18 1.795414500529385e-17 7.32016976457739e-18 9134/57060/2810/1869/6790/25904/1647/8900/55571/55835/57472/144455/85456/29883/1263/7027/7832/898/5934/890/10769/983/7157/5325/79733/1820/4869/4850/891/5111/246175/4848/23019/1874/1017/25946/4849/1027/9337/1026/5933/28984/2033/995/10498/581/3276 47 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 54/3952 59/10654 2.34418349281617e-18 1.808928261956478e-17 7.375267363363157e-18 5689/5682/143471/5705/5709/5695/84515/4998/5711/5683/990/5699/5702/5696/5691/7314/5718/23594/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/51053/5688/5687/5708/81620/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 54 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5689880 Ub-specific processing proteases 144/3952 220/10654 6.782417338363044e-18 5.2048495486111974e-17 2.122093938958603e-17 5689/5682/79594/7419/10474/7375/9817/6478/3091/143471/5705/11274/8239/5709/5695/4792/11047/4609/4194/4089/5711/4088/5683/408/64135/5699/8312/5702/8900/8975/57599/6881/51616/1540/80351/5696/5691/7314/5718/6314/90865/2648/5700/122706/5707/8737/55611/57646/23198/63967/9101/8517/993/890/7417/4092/1643/9861/23586/81847/7046/6502/5698/9146/5692/5713/5710/10454/219333/7157/9958/8313/5719/6233/9804/23770/8607/7874/23326/51651/93624/8237/4303/409/330/84101/5706/27005/7416/25862/9738/8658/84132/5714/79589/55288/27430/5688/9097/5687/5708/4087/63891/84749/7189/5704/7311/367/5694/9960/23358/5684/8295/5720/7186/6885/991/5690/2625/5717/9491/4086/1080/57695/10197/64750/7316/10213/8678/9100/5715/3416/5701/329/9099/5685/5686/5728/5716/5693/154/10254/5721/4193 144 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 75/3952 93/10654 7.212547850335898e-18 5.474442056894296e-17 2.2320107814096714e-17 8454/3725/9252/4790/1848/4792/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/5601/5606/8767/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/3665/351/79155/7867/64127/5602/57162/7189/7311/6416/51284/5595/5516/1147/6885/5604/10392/6500/246330/7099/4615/7316/7335/4793/3146/466/23291/6288/6285/5609/1385/5599/57161/148022 75 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-975155 MyD88 dependent cascade initiated on endosome 75/3952 93/10654 7.212547850335898e-18 5.474442056894296e-17 2.2320107814096714e-17 8454/3725/9252/4790/1848/4792/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/5601/5606/8767/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/3665/351/79155/7867/64127/5602/57162/7189/7311/6416/51284/5595/5516/1147/6885/5604/10392/6500/246330/7099/4615/7316/7335/4793/3146/466/23291/6288/6285/5609/1385/5599/57161/148022 75 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 43/3952 44/10654 7.361570385290726e-18 5.557185470200445e-17 2.2657464915826152e-17 892/7321/8239/9612/4609/4089/22938/23327/4088/1030/904/7314/5054/7027/6497/51592/7323/6667/4092/7050/5494/6233/1025/4221/3726/1024/60436/8812/1874/142/905/4087/7311/64750/54778/7316/1875/9611/5933/3065/6498/25937/23439 43 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1169408 ISG15 antiviral mechanism 62/3952 72/10654 8.856640124711682e-18 6.649661153094338e-17 2.7111649428704896e-17 3839/23165/5335/348995/57122/11274/23511/4734/23279/23225/3836/4599/9972/8021/7334/55746/7314/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/51191/6233/5610/6396/129401/4928/3838/5903/55706/7175/4600/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/7318/5595/3837/9631/79023/23636/7316/53371/9688/5300/9775/5495/8480 62 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-180585 Vif-mediated degradation of APOBEC3G 50/3952 54/10654 1.2674198573367967e-17 9.464764418498982e-17 3.85892407044254e-17 5689/5682/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/8065/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6783783 Interleukin-10 signaling 45/3952 47/10654 1.569517134419848e-17 1.1658071121439406e-16 4.75316756722701e-17 729230/7124/1437/3593/5743/941/3383/6349/3576/2920/1435/7133/3606/6347/3588/3569/3592/3587/6367/3976/3627/7076/7850/7297/3557/6351/6774/1440/3552/3716/1234/3586/3554/2208/3553/1230/2919/2357/6352/6348/6364/7132/942/6363/5724 45 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 74/3952 92/10654 1.587530063388706e-17 1.1729144989611238e-16 4.782145431708421e-17 8454/3725/9252/4790/1848/4792/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/5601/5606/8767/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/351/79155/7867/64127/5602/57162/7189/7311/6416/51284/5595/5516/1147/6885/5604/10392/6500/246330/7099/4615/7316/7335/4793/3146/466/23291/6288/6285/5609/1385/5599/57161/148022 74 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-75893 TNF signaling 42/3952 43/10654 1.9529872271587107e-17 1.43529061297537e-16 5.851891552277284e-17 7124/25999/7375/9530/8439/10616/6868/1540/3551/7314/257397/90268/81858/8737/55072/23118/841/8517/8887/7128/10454/6233/6610/8772/331/8717/84888/56928/330/27005/8567/7311/1147/7186/56957/6885/7316/7132/329/9099/55512/7185 42 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-674695 RNA Polymerase II Pre-transcription Events 69/3952 84/10654 2.324445199425888e-17 1.6992917800013464e-16 6.928263253690457e-17 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/11198/904/51497/4300/2959/404672/5438/83860/2068/1025/23168/6883/6829/2957/123169/25920/2963/5434/5436/9646/6878/4331/8148/2966/2962/4298/54457/8812/905/2071/6880/6908/6882/2961/5432/22916/55840/6877/6917/5440/902/6830/5430/6749/5441/4686/6872/6879/9150/2958/5437/6827/2968/138474/1022/8178 69 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-169911 Regulation of Apoptosis 49/3952 53/10654 3.190475065097064e-17 2.3201936468166607e-16 9.459771755426953e-17 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 49 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 51/3952 56/10654 3.599561715319747e-17 2.6040579284266293e-16 1.0617128305054956e-16 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/6469/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 51 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5387390 Hh mutants abrogate ligand secretion 53/3952 59/10654 3.6687130297716097e-17 2.6403328488874436e-16 1.0765026506774619e-16 5689/5682/143471/5705/5709/5695/3549/5711/5683/5699/5702/6469/5696/5691/7314/5718/5700/122706/5707/23198/50846/9861/5698/5692/5713/5710/5719/6233/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 53 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-167172 Transcription of the HIV genome 62/3952 73/10654 3.7545893958882326e-17 2.6882085932416264e-16 1.096022297877303e-16 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/11198/904/51497/2959/404672/5438/83860/2068/1025/6883/6829/2957/25920/2963/5434/5436/6878/4331/8148/2966/2962/54457/8812/905/2071/6880/6908/6882/2961/5432/22916/6877/6917/5440/902/5430/6749/5441/4686/6872/6879/9150/2958/5437/6827/2968/138474/1022/8178 62 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 77/3952 98/10654 4.395431170257892e-17 3.114925456881741e-16 1.2700010577866522e-16 8454/3725/9252/4790/1848/10333/4792/59307/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/5601/5606/11213/8767/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/79155/8651/7867/64127/5602/57162/7189/7311/6416/5595/5516/1147/6885/5604/10392/6500/246330/7099/4615/7316/7335/4793/3146/466/23291/114609/6288/6285/5609/1385/5599/7097/57161 77 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 77/3952 98/10654 4.395431170257892e-17 3.114925456881741e-16 1.2700010577866522e-16 8454/3725/9252/4790/1848/10333/4792/59307/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/5601/5606/11213/8767/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/79155/8651/7867/64127/5602/57162/7189/7311/6416/5595/5516/1147/6885/5604/10392/6500/246330/7099/4615/7316/7335/4793/3146/466/23291/114609/6288/6285/5609/1385/5599/7097/57161 77 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 65/3952 78/10654 4.689579292348468e-17 3.306510475671077e-16 1.3481130960638397e-16 3443/4790/7321/9140/9474/4792/3093/1387/64135/83737/7187/1540/3551/7314/3445/8737/29110/4214/9636/841/8517/3444/8887/7323/5970/23586/7128/3451/3448/3661/3439/51191/6233/10010/55593/8772/3452/4791/3446/3665/351/7706/843/3440/9246/7189/7311/7318/5094/9641/3456/1147/3441/7186/57506/3449/7316/4793/3146/7322/2033/6288/54941/6285/5300 65 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-194138 Signaling by VEGF 82/3952 107/10654 6.288857920750541e-17 4.411729117132577e-16 1.7987270395341795e-16 5295/4893/857/5335/71/5291/5578/8829/7423/1432/2534/3690/5603/2475/8440/9564/3845/3265/5062/5829/5879/26999/5290/5567/10006/5921/1500/9261/6714/10000/3728/5580/2324/3685/3791/3710/1535/5600/6300/801/10787/253260/805/5170/4688/5590/653361/6461/5747/7424/5568/3315/10451/7867/64223/5566/1003/10163/998/208/2185/387/60/5058/25759/558/1495/1499/4690/207/7422/10458/3708/9047/3320/4846/1398/9844/5228/5296/808/1536 82 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-450294 MAP kinase activation 56/3952 64/10654 7.305158617150857e-17 5.07343265961127e-16 2.0685133347511376e-16 8454/3725/9252/4790/1848/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/5601/5606/8767/5594/23118/8517/5528/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/79155/7867/64127/5602/7189/7311/6416/5595/5516/1147/6885/5604/10392/6500/7316/7335/466/23291/5609/1385/5599 56 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-4608870 Asymmetric localization of PCP proteins 56/3952 64/10654 7.305158617150857e-17 5.07343265961127e-16 2.0685133347511376e-16 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/1856/8322/23198/9861/5698/5692/5713/5710/5719/6233/7474/144165/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/50855/10197/64750/7316/10213/5715/5701/5685/5686/23513/5716/5693/5721 56 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5678895 Defective CFTR causes cystic fibrosis 54/3952 61/10654 8.345223224475031e-17 5.76692291482379e-16 2.351259541643135e-16 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/79139/91445/23198/9861/5698/5692/5713/5710/5719/10613/6233/5706/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 54 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 76/3952 97/10654 9.428868068885346e-17 6.483513736476112e-16 2.643424190234662e-16 8454/3725/9252/4790/1848/4792/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/5601/5606/8767/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/3665/351/8411/79155/7867/64127/5602/57162/7189/7311/6416/51284/5595/5516/1147/6885/5604/10392/6500/246330/7099/4615/7316/7335/4793/3146/466/23291/6288/6285/5609/1385/5599/57161/148022 76 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-909733 Interferon alpha/beta signaling 59/3952 69/10654 1.135199913289305e-16 7.767451623442585e-16 3.166904606428033e-16 3443/5777/5770/3107/9021/11274/3662/3106/4599/684/3133/91543/4938/5696/3445/9636/2634/3444/3434/3433/3451/3448/3661/3439/3452/4940/3437/6773/7297/5781/3430/3660/3446/3135/3665/10379/3455/4600/8638/3394/3663/6772/8651/3659/3440/3454/3716/3456/3105/3441/54739/2537/3449/3664/6041/1958/4939/6059/3134 59 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1852241 Organelle biogenesis and maintenance 179/3952 296/10654 1.1710184125280342e-16 7.973257720595292e-16 3.250814788132521e-16 5563/79867/7531/11190/203068/54801/51807/85302/347688/79441/53632/5116/7278/3313/5048/10576/5469/22832/10989/60412/8655/83658/9702/132320/1432/1387/25813/7846/7840/2101/11064/84902/81027/84808/10499/23054/5518/1386/55835/3054/23332/7019/93323/814/79861/10575/1454/9321/23408/51422/10013/54806/5465/91147/54927/983/64784/79959/2747/5310/4208/8729/10376/10540/11336/117177/57545/55902/26005/54930/54820/23322/6742/378/5600/1453/6300/801/9793/4218/133522/140735/805/6102/80173/84617/5442/11258/22981/8636/54903/80776/3418/7532/55125/10382/23410/121441/7277/9814/4209/23354/2553/146057/9738/1639/55722/4957/50807/5566/5571/7283/347733/4580/22919/27077/22994/4867/6648/1069/10651/5577/10383/5347/403/84790/22948/80184/22897/5564/23373/5565/5108/261734/57787/7280/10806/9657/1778/139322/115106/10694/22995/55559/8841/10142/51134/95681/200186/112714/7203/1781/80321/8766/9611/23409/79598/54205/10121/347240/84131/6950/3320/79600/10733/6256/4751/10498/80254/1385/26123/808/9662/55142/8648/8481/51259/55755/10891 179 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5610787 Hedgehog 'off' state 85/3952 113/10654 1.252329658614067e-16 8.4852970527558e-16 3.459580777069926e-16 8454/5689/5682/1452/51684/143471/5705/7278/5709/9978/5695/5711/7846/5683/5699/5702/81027/83737/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/5573/2737/5727/8650/9861/2932/5698/5692/5713/10376/5710/5719/6233/23322/115/84617/54903/10382/5568/7277/5706/5714/5566/2736/5688/5687/347733/5708/5577/5704/7311/10383/84790/5694/7280/5684/5720/2735/5575/5690/5717/9491/6500/7289/10197/7316/10213/2778/5715/5701/5576/5685/5686/5716/8481/5693/5721 85 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-4420097 VEGFA-VEGFR2 Pathway 77/3952 99/10654 1.2628323015782574e-16 8.514922654816503e-16 3.471659572044469e-16 5295/4893/857/5335/71/5291/5578/1432/2534/3690/5603/2475/8440/9564/3845/3265/5062/5829/5879/26999/5290/5567/10006/5921/1500/9261/6714/10000/3728/5580/3685/3791/3710/1535/5600/6300/801/10787/253260/805/5170/4688/5590/653361/6461/5747/5568/3315/10451/7867/64223/5566/1003/10163/998/208/2185/387/60/5058/25759/558/1495/1499/4690/207/7422/10458/3708/9047/3320/4846/1398/9844/5296/808/1536 77 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-76002 Platelet activation, signaling and aggregation 162/3952 262/10654 1.8672084286919287e-16 1.2529239166440042e-15 5.108355629983513e-16 5295/5777/2153/5770/5291/7042/2770/5175/3959/5578/5582/5908/3082/29106/7423/1432/3920/374354/2244/7114/3309/2534/3690/408/2162/2768/2782/87/5894/10487/2885/7040/9564/54863/350/7043/2773/5879/5054/5099/1072/5290/7018/6678/5340/7225/5336/813/7094/5594/10681/7414/10490/83706/7044/7534/6810/7123/6714/6694/3671/7273/22927/1191/9749/3273/27154/226/2335/1/2783/1445/8525/5478/2771/22915/5580/2266/5154/3932/7076/2243/3710/801/5781/2151/2147/805/5170/5590/351/6464/5747/51097/7424/2316/5552/409/6915/2157/7277/10451/334/1277/335/308/6850/78991/8503/6403/197/4067/81/998/3481/6654/5473/8407/7450/387/29789/10916/5595/139322/7066/5321/5005/59345/207/7422/5004/3708/5196/3827/1950/2621/5216/5768/710/6647/4352/5265/7078/391/5345/54676/2/1398/88/1675/5906/3479/5155/5296/5581/51368/808/213/7057/1278/5627/10672 162 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 47/3952 51/10654 2.0117388015624365e-16 1.3434159593126077e-15 5.477305036642666e-16 6227/6206/6234/27335/6191/8668/6224/8662/6202/6218/6192/3921/8665/6208/6203/8666/6222/8667/6231/8663/8894/6207/6233/51386/6188/1968/6230/6194/6232/6193/6210/6229/6205/6235/6223/6187/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 47 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 42/3952 44/10654 2.750642118838092e-16 1.82805832682589e-15 7.453263459757711e-16 834/79370/55367/472/1387/51499/8738/7159/637/27166/23368/332/64065/8797/7157/604/63970/839/317/5875/55240/5366/84883/147923/843/94241/8626/7161/10397/8795/665/27113/9540/8793/835/58484/3486/355/8794/124446/5876/581 42 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5358346 Hedgehog ligand biogenesis 56/3952 65/10654 3.371892167240995e-16 2.2302658191894007e-15 9.093122736720078e-16 5689/5682/143471/5705/5709/5695/3549/5711/5683/5699/5702/6868/6469/5696/5691/7314/5718/5700/122706/5707/23198/50846/9861/5698/5692/5713/5710/5719/6233/5706/84447/5714/5688/5687/5708/5704/7311/147111/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721/5034 56 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 46/3952 50/10654 5.038497839912888e-16 3.3168120851369675e-15 1.3523132142046066e-15 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/2209/5706/5714/5688/5687/5708/5704/5694/5684/5720/5690/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721/4360 46 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5632684 Hedgehog 'on' state 68/3952 85/10654 5.575374835545468e-16 3.652922474798422e-15 1.4893503781149265e-15 5689/5682/22873/1452/51684/143471/5705/8452/5709/9978/5695/3549/5711/5683/408/5699/5702/83737/6469/5696/5691/7314/5718/339745/5700/122706/5707/23198/2737/5727/8650/50846/9861/8405/5698/5692/5713/5710/5719/6233/409/5706/5714/2736/5688/5687/5708/5704/7311/5694/57154/5684/5720/2735/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/5716/5693/5721 68 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2219528 PI3K/AKT Signaling in Cancer 77/3952 101/10654 9.41929220461465e-16 6.1424398461078626e-15 2.504363333868388e-15 5295/2308/374/5291/7039/3082/941/2064/2534/9965/2264/2885/2475/8660/2252/5879/1839/5290/3667/2065/3815/2069/8074/7249/2260/6714/2099/2248/2932/2247/10000/2246/5154/3932/2931/5781/940/253260/5170/572/4303/930/6199/2263/4233/64223/8503/5159/29851/208/9365/5293/1956/2549/1147/2309/842/207/1027/2100/2254/1950/1026/10818/2261/2255/3164/391/5728/2066/942/1385/5155/4254/5296/5156/4193 77 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-72649 Translation initiation complex formation 51/3952 58/10654 1.158423249414259e-15 7.483952992727469e-15 3.0513180327288683e-15 6227/6206/6234/27335/6191/8668/6224/8662/26986/6202/6218/6192/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/6233/51386/6188/1968/6230/6194/6232/6193/6210/6229/6205/6235/1975/6223/6187/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 51 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-72702 Ribosomal scanning and start codon recognition 51/3952 58/10654 1.158423249414259e-15 7.483952992727469e-15 3.0513180327288683e-15 6227/6206/6234/27335/6191/8668/6224/8662/6202/6218/6192/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/6233/51386/6188/1968/6230/6194/1983/6232/6193/6210/6229/6205/6235/1975/6223/6187/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 51 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 49/3952 55/10654 1.2919692591868573e-15 8.30808009727104e-15 3.387326810148778e-15 834/4790/7295/29108/1432/10628/5603/83737/3654/64170/7334/1540/3551/7314/257397/8767/23118/841/8517/5970/7128/837/598/10454/6233/5600/6300/5608/4791/351/330/64127/7189/3326/4210/7311/114548/1147/9447/596/6885/842/10392/835/58484/7316/7335/22861/329 49 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2408522 Selenoamino acid metabolism 86/3952 118/10654 2.152521597734041e-15 1.3778122116371351e-14 5.617543631243823e-15 6158/6138/6227/6206/6234/6191/6128/6132/6129/9255/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6192/6156/6143/6139/3921/6208/6170/7296/6203/6147/191/6222/6134/6155/6231/6142/23521/6207/6233/6188/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/9521/6217/6152/51065/6141/6164/6209/11224/6165/6130/6204/6228/7965/6124/6189/6135/6201/6133 86 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-4615885 SUMOylation of DNA replication proteins 42/3952 45/10654 2.6417473195710475e-15 1.6832050582037545e-14 6.862675315930584e-15 23165/9212/348995/6613/57122/23511/6790/23279/23225/9972/6612/8021/55746/7150/51588/3619/7153/332/10762/79902/9883/7155/6396/129401/4928/5903/55706/7175/5111/4927/8086/7329/5905/55143/9631/79023/23636/53371/9688/7341/10401/8480 42 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 55/3952 65/10654 3.285912734398041e-15 2.0840788986661548e-14 8.497097097361914e-15 3725/4436/472/5431/5435/5433/2965/5439/672/2967/1386/11198/904/51497/2176/404672/5438/1643/9656/2177/2068/7157/1025/2353/6829/25920/2963/5434/5436/4292/4331/2966/2962/8812/905/1111/2071/55215/5432/6917/5440/8621/902/5430/6749/545/5441/5395/9150/5437/51755/6827/2968/1022/8178 55 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69002 DNA Replication Pre-Initiation 67/3952 85/10654 3.669188444067069e-15 2.3165921585496177e-14 9.445087956498006e-15 5689/5682/143471/5705/5709/5422/1869/4174/5695/84515/4998/5711/5683/990/5699/5702/55388/6117/5696/5691/7314/5718/6118/23594/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/4172/8318/4173/5706/5714/51053/6119/5688/5687/5708/81620/5704/7311/5694/4176/1017/5684/5720/5690/5717/9491/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 67 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 51/3952 59/10654 5.463415528056184e-15 3.433793741389158e-14 1.4000083610832234e-014 6227/6206/6234/27335/6191/8668/6224/8662/26986/6202/6218/6192/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/6233/51386/6188/1968/6230/6194/6232/6193/6210/6229/6205/6235/1975/6223/6187/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 51 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8943724 Regulation of PTEN gene transcription 52/3952 61/10654 1.0041215126198223e-14 6.282544058688888e-14 2.56148588804867e-14 1912/3725/6591/1822/9112/6045/80012/1911/5928/23512/57332/1107/2475/1386/10670/23186/2146/51564/5594/84232/7101/84733/57459/3066/7157/8726/57521/6015/389541/9219/8535/5931/1108/2122/64223/10014/54815/6009/57504/648/23466/53615/5595/8841/5468/5978/57167/1958/6615/3065/23028/10542 52 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5696398 Nucleotide Excision Repair 81/3952 111/10654 1.255999877471464e-14 7.823245873577864e-14 3.189652745242614e-14 2074/5982/6613/7507/5431/5435/9978/5433/10980/57654/2965/5439/10987/2067/2967/6612/6117/7334/10714/7314/6118/404672/86/5438/1643/5985/10920/2068/5984/6233/8607/7874/5886/8451/8554/5434/5436/7515/8450/4331/5111/2966/6119/1161/1642/142/2071/1069/7329/51426/2873/7311/3980/60/8533/5983/10038/5432/51138/7528/9318/6917/5440/902/5430/5441/7336/54778/7316/64708/7341/5437/10401/2033/2968/5887/5981/1022/8178/50813/7508 81 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-168325 Viral Messenger RNA Synthesis 40/3952 43/10654 1.6940500378080417e-14 1.0504622779086472e-13 4.282889663255294e-14 23165/348995/57122/5431/23511/5435/5433/23279/23225/5439/9972/8021/55746/5438/10762/79902/9883/6396/129401/4928/2963/5434/5903/55706/7175/5436/4927/2962/8086/5432/5440/9631/5430/79023/5441/23636/53371/9688/5437/8480 40 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5358351 Signaling by Hedgehog 101/3952 149/10654 2.0152480021209024e-14 1.244079766642637e-13 5.072296725806061e-14 8454/5689/5682/22873/1452/51684/143471/5705/7278/8452/5709/9978/5695/3549/5711/7846/5683/408/5699/5702/81027/83737/6868/6469/5696/5691/7314/5718/8945/339745/5700/122706/5707/5567/23198/5573/2737/5727/8650/50846/9861/8405/2932/5698/5692/5713/10376/5710/5719/6233/23322/115/84617/54903/10382/5568/409/7277/5706/84447/5714/5566/2736/5688/5687/347733/5708/5577/5704/7311/147111/10383/84790/5694/7280/57154/5684/5720/2735/5575/5690/5717/9491/6500/7289/10197/64750/7316/10213/2778/7415/5715/5701/5576/5685/5686/5716/8481/5693/5721/5034 101 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-447115 Interleukin-12 family signaling 49/3952 57/10654 3.013323751067551e-14 1.8519941107224905e-13 7.550853181529309e-14 3593/5908/1265/3313/6175/5898/3717/3181/4001/3594/4282/5062/3572/10148/1072/3592/6627/9049/27250/9987/3185/149233/3458/5478/302/552900/51561/7297/6775/3595/821/4478/6774/6772/998/6648/3716/2939/246778/3586/829/5055/6647/6950/9466/6845/375/5721/5034 49 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 76/3952 103/10654 3.0866822365984485e-14 1.8887231835397555e-13 7.70060302939933e-14 5295/374/3643/5291/5526/7039/3082/941/2064/2534/9965/2264/3630/3654/2885/8660/5518/2252/5879/5515/23396/1839/5290/3667/90865/2065/3815/5594/2069/8074/2260/5528/6714/2099/2248/5519/2247/2246/5154/3932/8394/5781/940/930/2263/4233/8503/5159/29851/5529/7189/9365/5293/1956/2549/5595/3556/5516/5525/8870/207/4615/2100/2254/1950/10818/2261/2255/391/2066/942/5527/5155/4254/5296/5156 76 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 61/3952 77/10654 4.185113681197678e-14 2.549615308413849e-13 1.039515771230079e-13 1912/23165/7486/6045/80012/10274/348995/6613/57122/23511/1911/6672/23279/23225/57332/5371/8924/672/9972/6612/8021/6117/55746/51564/51588/10762/79902/9656/9883/84733/9063/6396/129401/6015/8554/4928/5903/55706/7175/1029/8535/5885/641/4927/8243/142/1069/8086/7329/648/9631/79023/23636/10735/53371/6996/9688/7341/9126/8480/7508 61 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-448424 Interleukin-17 signaling 58/3952 72/10654 4.532677177196338e-14 2.749296331495945e-13 1.120928669883535e-13 8454/3605/3725/9252/4790/1848/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/5601/5606/8767/5594/23118/8517/5528/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/79155/7867/64127/5602/7189/112744/7311/6416/5595/5516/1147/6885/5604/10392/6500/7316/7335/466/23291/5609/1385/5599 58 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-351202 Metabolism of polyamines 50/3952 59/10654 5.3878458539631605e-14 3.253790387458622e-13 1.3266183384128974e-13 5689/5682/143471/5705/5709/5695/5711/4946/5683/5699/5702/5696/5691/5718/1728/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6303/5706/4947/5714/5688/5687/5708/4953/5704/5694/5684/5720/5690/51686/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 50 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-109606 Intrinsic Pathway for Apoptosis 46/3952 53/10654 8.837883123471626e-14 5.314207644373199e-13 2.1666808477683919e-13 7531/55075/10971/7533/2810/1869/8655/836/840/7159/637/578/23368/7027/5594/841/7534/4836/598/10000/708/3002/7157/331/317/140735/1029/572/7532/6774/5366/56616/8626/208/7161/7529/5595/27113/596/10018/842/207/54205/5534/581/5599 46 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-199418 Negative regulation of the PI3K/AKT network 79/3952 110/10654 1.1272797193296799e-13 6.749101423055713e-13 2.7517082078011246e-13 5295/374/3643/5291/5526/7039/3082/941/2064/2534/9965/2264/3630/3654/2885/8660/5518/2252/5879/5515/23396/1839/5290/3667/90865/2065/3815/5594/2069/8074/2260/5528/6714/2099/2248/5519/2247/10000/2246/5154/3932/8394/5781/940/930/2263/4233/8503/5159/29851/5529/7189/208/9365/5293/1956/2549/5595/3556/5516/5525/8870/207/4615/2100/2254/1950/10818/2261/2255/391/5728/2066/942/5527/5155/4254/5296/5156 79 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1226099 Signaling by FGFR in disease 52/3952 63/10654 1.4582857319926543e-13 8.693385758531317e-13 3.544421611981243e-13 5295/4893/11052/5335/9530/613/5431/6776/5435/5433/11064/5439/2264/2885/2252/3845/3265/7750/8805/26127/5290/8074/2260/5438/2248/399687/2247/2246/6777/1523/2963/5434/5436/9208/6774/2263/6772/2962/6654/11160/2549/5432/22916/5440/5430/5441/2254/4686/10818/2261/5437/2255 52 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8878171 Transcriptional regulation by RUNX1 144/3952 239/10654 1.8258211974575395e-13 1.0837887364395396e-12 4.4187665507519403e-13 1912/9070/5689/1437/5682/1459/6045/9021/5929/27327/80012/1460/143471/5705/5709/5695/28996/1457/1911/6603/10413/5711/1387/3558/5683/10138/57332/5699/8312/5702/192669/83737/5371/57492/6688/4343/5696/5691/7314/5718/84661/25/4773/5700/122706/5707/23198/86/100506658/865/7082/23309/6714/2099/9861/8850/84733/8289/5698/5692/5713/6602/595/5710/3458/896/5719/6233/26523/5781/1493/23429/6015/55904/6595/3562/6597/6929/8535/3958/5706/6599/200845/4331/5714/5688/5687/5708/4602/5704/7311/7161/860/58508/25942/648/5694/6601/23466/4297/27161/894/5684/5720/902/2624/11091/640/5690/2625/57690/5717/9491/4005/6598/10197/192670/5196/7316/10213/10398/122809/5715/5701/5685/5686/2033/1021/6605/50943/3065/861/23112/9757/5716/9739/8784/3276/3977/3559/7057/1022/5693/5721 144 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6806003 Regulation of TP53 Expression and Degradation 35/3952 37/10654 2.099611248577158e-13 1.2410042656483713e-12 5.059757454577878e-13 11200/472/639/4194/8900/2475/5518/51230/7314/5515/6446/117584/890/983/5519/10000/900/7157/6233/7874/253260/5170/1029/80196/64223/1616/208/7311/5516/1017/207/7316/9099/5527/4193 35 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5696395 Formation of Incision Complex in GG-NER 39/3952 43/10654 2.9475599082522154e-13 1.7348138612552232e-12 7.073092018910313e-13 6613/7507/9978/2965/2067/2967/6612/6117/7334/7314/6118/404672/1643/2068/6233/5886/8451/8554/8450/4331/2966/6119/1642/142/2071/1069/7329/7311/10038/902/7336/54778/7316/7341/10401/2968/5887/1022/7508 39 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5617833 Cilium Assembly 125/3952 201/10654 2.9876158079247843e-13 1.7509697709736394e-12 7.138962046029465e-13 79867/7531/11190/203068/54801/51807/85302/347688/79441/5116/7278/5048/10576/22832/60412/8655/83658/9702/132320/7846/7840/11064/84902/81027/5518/55835/23332/93323/79861/10575/1454/9321/10013/54806/91147/983/79959/5310/8729/10376/10540/11336/117177/57545/26005/54930/54820/23322/378/1453/9793/4218/140735/6102/80173/84617/11258/22981/8636/54903/80776/7532/55125/10382/121441/7277/9814/23354/146057/9738/1639/55722/4957/50807/5566/7283/347733/22919/27077/22994/4867/1069/5577/10383/5347/403/84790/22948/80184/22897/5108/261734/57787/7280/10806/9657/1778/115106/10694/22995/55559/10142/51134/95681/112714/7203/1781/80321/8766/79598/10121/347240/84131/6950/3320/79600/10733/4751/80254/26123/9662/55142/8481/51259/55755 125 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5357905 Regulation of TNFR1 signaling 32/3952 33/10654 3.231950079212271e-13 1.8862095210192624e-12 7.690354456506865e-13 7124/25999/7375/10616/1540/3551/7314/90268/81858/8737/55072/841/8517/8887/7128/6233/331/8717/84888/56928/330/27005/8567/7311/1147/7186/56957/7316/7132/329/9099/7185 32 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 61/3952 79/10654 3.441992579818027e-13 2.0003881562206024e-12 8.155877594988324e-13 2074/5982/7507/5431/5435/9978/5433/10980/57654/2965/5439/10987/2067/2967/6117/10714/7314/6118/404672/5438/5985/10920/2068/5984/6233/7874/8451/5434/5436/7515/8450/4331/5111/2966/6119/1161/1642/2071/51426/2873/7311/3980/8533/5983/5432/51138/9318/6917/5440/902/5430/5441/7316/64708/5437/2033/2968/5981/1022/8178/50813 61 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 46/3952 54/10654 3.8184545569723397e-13 2.2099305748477414e-12 9.010212945838241e-13 2074/7507/5431/5435/9978/5433/10980/57654/2965/5439/10987/2967/7314/404672/5438/10920/2068/6233/7874/8451/5434/5436/8450/4331/2966/1161/1642/2071/2873/7311/8533/5432/51138/9318/6917/5440/902/5430/5441/7316/64708/5437/2033/2968/1022/50813 46 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-168638 NOD1/2 Signaling Pathway 34/3952 36/10654 5.387526519655299e-13 3.092262122231905e-12 1.2607608819376039e-12 834/1432/5603/83737/3654/64170/7334/1540/3551/7314/257397/8767/23118/841/8517/7128/837/10454/6233/5600/6300/5608/330/64127/7189/7311/1147/6885/842/10392/835/7316/7335/329 34 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6804757 Regulation of TP53 Degradation 34/3952 36/10654 5.387526519655299e-13 3.092262122231905e-12 1.2607608819376039e-12 11200/472/4194/8900/2475/5518/51230/7314/5515/6446/117584/890/983/5519/10000/900/7157/6233/7874/253260/5170/1029/80196/64223/1616/208/7311/5516/1017/207/7316/9099/5527/4193 34 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 42/3952 48/10654 6.001330300886385e-13 3.4303900361856745e-12 1.3986206202628874e-12 5295/5777/1437/5291/6776/3558/3717/2534/3563/2885/1399/7314/5290/1439/7534/3718/3567/6233/7525/6777/5781/3562/6464/1438/6850/5566/8503/2889/4067/3636/6654/3716/7311/5293/3561/7316/3560/3055/867/1398/5296/3559 42 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2682334 EPH-Ephrin signaling 68/3952 92/10654 6.123379491020136e-13 3.485809062715971e-12 1.421215774878703e-12 71/2042/1947/1212/23385/2051/10094/2050/79784/2047/2534/1948/8976/163/1759/8440/8874/3265/5062/5879/1072/161/10093/5921/6453/4313/102/6714/7525/1942/1213/1211/1175/10109/5663/1173/2904/5747/7074/1949/10627/10451/4318/160/2049/8218/10092/4067/2044/6386/998/2048/10097/387/60/5058/4629/28964/4627/6383/10398/10552/4637/1946/10096/1944/10095/1969 68 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 31/3952 32/10654 8.494707327762114e-13 4.8159789707190104e-012 1.9635456680283643e-12 892/4609/4089/22938/4088/1030/904/7314/5054/7027/6667/4092/7050/6233/1025/4221/3726/1024/60436/8812/1874/905/4087/7311/54778/7316/1875/5933/3065/25937/23439 31 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 41/3952 47/10654 1.4271027121832326e-12 7.992926077510121e-12 3.2588338673793688e-12 8454/892/3091/9978/9759/9612/4609/22938/1387/9794/388585/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/8850/3066/6233/10046/1024/10014/7088/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 41 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-437239 Recycling pathway of L1 41/3952 47/10654 1.4271027121832326e-12 7.992926077510121e-12 3.2588338673793688e-12 9252/71/7430/51807/347688/1785/7278/7846/81027/6456/5962/163/6196/1759/6197/8986/161/79861/5594/8650/6714/10376/6195/1213/1211/1175/1173/84617/10382/7277/4478/160/26052/27330/347733/10383/24137/60/84790/7280/112714 41 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-4570464 SUMOylation of RNA binding proteins 41/3952 47/10654 1.4271027121832326e-12 7.992926077510121e-12 3.2588338673793688e-12 1912/23165/6045/80012/348995/6613/57122/23511/3190/1911/23279/23225/57332/9972/8021/55746/51602/10762/79902/9883/84733/6396/129401/6015/4928/5903/55706/7175/8535/4927/8086/7329/648/9631/79023/23636/3183/53371/9688/7341/8480 41 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-451927 Interleukin-2 family signaling 39/3952 44/10654 1.6626104446105863e-12 9.200660986311174e-12 3.751245205286205e-12 5295/5777/1437/5291/6776/84868/3558/3717/3563/2885/3600/5290/1439/50615/3718/3567/3932/6777/59067/3562/6464/6775/1438/3581/6774/6850/6772/8503/3636/6654/3716/5293/2185/3561/3578/3560/5296/3559/3601 39 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69231 Cyclin D associated events in G1 39/3952 44/10654 1.6626104446105863e-12 9.200660986311174e-12 3.751245205286205e-12 8454/5925/1869/5753/1031/3717/5520/1030/5518/7314/5515/25/7027/5934/6714/5519/6502/595/896/6233/1163/1019/1029/4331/4067/1874/7311/5516/894/902/1027/6500/7316/1875/1026/5933/1021/1022/1028 39 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69236 G1 Phase 39/3952 44/10654 1.6626104446105863e-12 9.200660986311174e-12 3.751245205286205e-12 8454/5925/1869/5753/1031/3717/5520/1030/5518/7314/5515/25/7027/5934/6714/5519/6502/595/896/6233/1163/1019/1029/4331/4067/1874/7311/5516/894/902/1027/6500/7316/1875/1026/5933/1021/1022/1028 39 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-3232142 SUMOylation of ubiquitinylation proteins 35/3952 38/10654 1.7064162602918153e-12 9.405603910894172e-12 3.834803458801156e-12 23165/348995/57122/23511/23279/23225/7428/5371/9972/8021/55746/51588/10762/79902/9883/9063/6396/129401/8554/4928/5903/55706/7175/4927/8086/7329/9631/79023/23636/53371/9688/7341/5987/8480/4193 35 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-177929 Signaling by EGFR 42/3952 49/10654 2.6912049904379615e-12 1.4775034512720667e-11 6.023999520930408e-12 5295/374/4893/5335/7039/55824/6456/6868/30011/2885/8874/3845/3265/10252/5829/7314/1839/5290/8027/2060/2069/102/6714/9146/6455/1445/6233/29924/5781/6464/5782/998/6654/7311/1956/2549/58513/7316/1950/867/10254/6457 42 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5685938 HDR through Single Strand Annealing (SSA) 34/3952 37/10654 4.265056625854064e-12 2.3323478950044468e-11 9.509326418190993e-12 83990/9156/1763/7486/5982/472/4683/84126/2067/672/6117/83695/6118/25/5888/116028/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/5983/5883/10111/545/5932/7156 34 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 29/3952 30/10654 5.8486119375081256e-12 3.173328898905776e-11 1.293813002623097e-11 7124/7375/10616/1540/3551/7314/257397/81858/8737/55072/23118/8517/7128/10454/6233/331/8717/330/27005/7311/1147/7186/56957/6885/7316/7132/329/9099/7185 29 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 29/3952 30/10654 5.8486119375081256e-12 3.173328898905776e-11 1.293813002623097e-11 11065/7321/65264/8239/55236/3093/7347/7328/7332/7314/90268/10477/92912/29089/7324/6233/7874/7326/7317/7327/7311/997/7319/7320/7316/54926/7322/55284/27338 29 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 62/3952 84/10654 7.1692827857666975e-12 3.8747602293501725e-11 1.579796903027845e-11 5982/6613/7507/9978/10980/2965/10987/2067/2967/6612/6117/7334/10714/7314/6118/404672/86/1643/5985/10920/2068/5984/6233/8607/5886/8451/8554/7515/8450/4331/5111/2966/6119/1642/142/2071/1069/7329/51426/2873/7311/3980/60/8533/5983/10038/51138/7528/9318/902/7336/54778/7316/64708/7341/10401/2968/5887/5981/1022/50813/7508 62 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-400253 Circadian Clock 54/3952 70/10654 8.476037443326214e-12 4.56326201890702e-11 1.8605092388859666e-11 8454/28999/3091/5469/1387/150094/2155/5499/10499/23054/1386/9575/23411/7314/5054/8945/10135/1454/5465/64784/4208/56938/6233/8864/1453/5500/5187/26224/1407/4783/406/4209/5501/8553/2908/1390/7311/23373/6095/8841/4862/6500/200186/6720/7316/9611/2033/79365/6256/10498/1385/8648/551/10891 54 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-113418 Formation of the Early Elongation Complex 31/3952 33/10654 9.006744468028488e-12 4.793244469766885e-11 1.9542764766280814e-11 5431/5435/5433/2965/5439/2967/51497/404672/5438/2068/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/4686/9150/5437/6827/2968/1022 31 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 31/3952 33/10654 9.006744468028488e-12 4.793244469766885e-11 1.9542764766280814e-11 5431/5435/5433/2965/5439/2967/51497/404672/5438/2068/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/4686/9150/5437/6827/2968/1022 31 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9022692 Regulation of MECP2 expression and activity 31/3952 33/10654 9.006744468028488e-12 4.793244469766885e-11 1.9542764766280814e-11 2290/817/9212/27327/28996/9612/192669/4204/4343/814/818/3066/26523/801/805/3930/5566/816/25942/27161/815/8841/57690/192670/9611/2874/3064/3065/23112/1385/808 31 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6806834 Signaling by MET 59/3952 79/10654 1.0070767715586598e-11 5.3390444110495355e-11 2.1768071639154644e-11 5295/4893/5770/10653/5908/3082/1280/1289/3688/3910/6456/30011/2885/3845/3265/1399/7314/5879/3918/5290/8027/2060/284217/9101/6714/9146/6455/2335/3909/6233/5781/6464/85440/5747/1277/3912/6774/4233/5795/2889/5771/3913/6654/5867/7311/2549/10048/7316/3915/1281/3673/867/3914/1398/5906/23163/1278/10254/6457 59 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-177243 Interactions of Rev with host cellular proteins 33/3952 36/10654 1.063466885373854e-11 5.616560850890811e-11 2.2899547101506244e-11 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/5902/7514/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/1104/5905/3837/9631/79023/23636/53371/9688/8480 33 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 45/3952 55/10654 1.1970637496344753e-11 6.298187682735933e-11 2.5678640243355178e-11 51807/347688/7278/1780/3305/8655/832/7846/81027/3306/3312/3303/79861/3337/10376/3301/10540/140735/84617/5241/11258/1783/10382/10294/7277/1639/2908/347733/51143/3326/367/10383/84790/3304/7280/10728/829/1778/112714/1781/10121/3320/10963/55466/2288 45 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-438064 Post NMDA receptor activation events 60/3952 81/10654 1.2142477583977854e-11 6.364491080809525e-11 2.594896897787522e-11 5563/4893/51807/817/347688/53632/7278/7846/81027/1739/6196/8874/6197/3845/3265/814/5879/818/57554/79861/5567/5594/51422/5573/6714/10376/6195/801/805/5170/84617/3838/2904/10382/5568/7277/5566/5571/27330/347733/816/5577/5562/10383/84790/5564/5565/7280/5595/815/28964/5575/112714/5576/4137/2066/88/1385/808/8536 60 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 40/3952 47/10654 1.4560259451048046e-11 7.490444584261385e-11 3.053964750356277e-11 4893/71/817/5908/5605/5037/3717/2244/3690/408/5894/8826/4140/3845/3265/818/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/409/673/816/7450/60/7529/5595/815/5604/10256/5906/808/5245 40 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6802949 Signaling by RAS mutants 40/3952 47/10654 1.4560259451048046e-11 7.490444584261385e-11 3.053964750356277e-11 4893/71/817/5908/5605/5037/3717/2244/3690/408/5894/8826/4140/3845/3265/818/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/409/673/816/7450/60/7529/5595/815/5604/10256/5906/808/5245 40 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 40/3952 47/10654 1.4560259451048046e-11 7.490444584261385e-11 3.053964750356277e-11 4893/71/817/5908/5605/5037/3717/2244/3690/408/5894/8826/4140/3845/3265/818/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/409/673/816/7450/60/7529/5595/815/5604/10256/5906/808/5245 40 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9020591 Interleukin-12 signaling 40/3952 47/10654 1.4560259451048046e-11 7.490444584261385e-11 3.053964750356277e-11 3593/5908/1265/3313/6175/5898/3717/3181/4001/3594/4282/5062/1072/3592/6627/9049/27250/9987/3185/3458/5478/302/552900/7297/6775/3595/4478/998/6648/3716/2939/3586/829/5055/6647/6950/6845/375/5721/5034 40 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9649948 Signaling downstream of RAS mutants 40/3952 47/10654 1.4560259451048046e-11 7.490444584261385e-11 3.053964750356277e-11 4893/71/817/5908/5605/5037/3717/2244/3690/408/5894/8826/4140/3845/3265/818/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/409/673/816/7450/60/7529/5595/815/5604/10256/5906/808/5245 40 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-186763 Downstream signal transduction 28/3952 29/10654 1.5318568829890003e-11 7.851473101371665e-11 3.201161402400786e-11 5295/4893/5335/5291/6776/2885/8440/9564/3845/3265/1399/5290/5921/6778/6714/5154/6777/5781/6774/6772/2889/5159/6654/4690/1398/5155/5296/5156 28 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 25/3952 25/10654 1.6285777189916702e-11 8.316523719409668e-11 3.3907693994486016e-11 11065/7321/8697/51529/29945/51434/9184/29882/7314/996/51433/119504/7324/64682/6233/246184/8881/10393/7311/25906/991/7316/4085/4751/701 25 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2173789 TGF-beta receptor signaling activates SMADs 30/3952 32/10654 2.294191377608292e-11 1.1587752085446972e-10 4.724497458959851e-11 25805/4738/9372/4089/23327/4088/5499/7040/7314/4092/11171/7046/2280/9958/9040/6233/7514/5500/5501/23645/4087/7048/7311/57154/51377/10273/5045/64750/7316/867 30 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 30/3952 32/10654 2.294191377608292e-11 1.1587752085446972e-10 4.724497458959851e-11 51807/7278/10576/7846/7411/81027/10574/10693/5201/79861/5204/10575/10471/10376/5202/84617/10382/7277/347733/10383/60/84790/22948/7280/10694/5203/112714/7203/908/6950 30 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5626467 RHO GTPases activate IQGAPs 30/3952 32/10654 2.294191377608292e-11 1.1587752085446972e-10 4.724497458959851e-11 71/6249/51807/347688/7278/7846/81027/8826/5879/79861/999/10376/128239/801/4221/805/84617/10382/7277/347733/998/10788/10383/60/84790/7280/1495/1499/112714/808 30 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-73887 Death Receptor Signalling 91/3952 141/10654 2.7444802372747767e-11 1.3811895107154583e-10 5.6313133777796724e-11 7124/25999/4790/7531/29/356/7375/9530/8878/1894/23385/4792/8439/836/23365/10616/3654/6868/8874/1540/3551/7314/5879/257397/90268/81858/8737/8767/55072/23118/841/8517/8887/6453/9828/5970/8797/7128/396/10454/3066/6233/6610/26574/8772/331/8717/8743/5663/84888/56928/572/27237/7074/330/10451/27005/843/8837/8567/7189/6654/7311/387/8795/1147/4804/57142/8841/7186/56957/6885/5584/10018/8793/835/9459/355/23421/23370/4615/7316/7132/329/9099/4803/3065/55512/5599/7185/10672 91 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5654738 Signaling by FGFR2 55/3952 73/10654 2.821612834457553e-11 1.4148809483976683e-10 5.768678339115196e-11 5295/4893/5335/54845/5431/5435/5433/5439/2885/7073/5518/2252/3845/3265/7314/5515/5290/5594/8074/5438/3185/6714/2248/4670/2247/6233/2246/5781/5725/2963/5434/6464/5436/673/2263/2962/6654/7311/2549/5432/22916/5595/5516/5440/5430/3178/5441/2254/4686/7316/10818/867/5437/2255/3187 55 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-982772 Growth hormone receptor signaling 24/3952 24/10654 4.407276260916851e-11 2.2020527792854337e-10 8.978094011258108e-11 5777/5770/9021/6776/3717/5618/6868/8660/1154/3667/2690/5594/5617/8835/6777/6774/6772/8651/1442/4067/2689/5595/25970/2688 24 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-165054 Rev-mediated nuclear export of HIV RNA 31/3952 34/10654 6.561074355362196e-11 3.254761528427889e-10 1.3270142869116024e-10 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/5902/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/1104/5905/9631/79023/23636/53371/9688/8480 31 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-4085377 SUMOylation of SUMOylation proteins 31/3952 34/10654 6.561074355362196e-11 3.254761528427889e-10 1.3270142869116024e-10 23165/348995/6613/57122/23511/23279/23225/9972/8021/55746/51588/10762/79902/9883/6396/129401/4928/5903/55706/7175/10210/4927/8086/7329/9631/79023/23636/53371/9688/7341/8480 31 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-3899300 SUMOylation of transcription cofactors 38/3952 45/10654 7.762714033871178e-11 3.8371565099811625e-10 1.5644653119395747e-10 1912/6045/80012/6613/28996/9612/1911/1387/57332/4152/115426/10499/6612/11315/3622/51588/1655/84733/10155/9063/7690/6015/8554/8535/4869/10210/10521/1616/7329/25942/648/1487/7341/10401/2033/6294/8648/10891 38 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-190236 Signaling by FGFR 62/3952 87/10654 8.631464526004193e-11 4.251455399510576e-10 1.7333810806234624e-10 5295/4893/5335/54845/5431/5435/5433/9965/5439/2264/2885/7073/5518/2252/3845/3265/7314/5515/5290/5594/8074/2260/5438/3185/6714/2248/4670/2247/6233/2246/200734/5781/5725/2963/5434/6464/5436/673/2263/2962/9365/6654/7311/2549/5432/22916/5595/5516/5440/5430/3178/5441/2254/4686/7316/10818/2261/867/5437/2255/3187/161742 62 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-168253 Host Interactions with Influenza Factors 36/3952 42/10654 1.0328827643498555e-10 5.051669576344892e-10 2.05964020467095e-10 3839/23165/348995/57122/23511/23279/23225/3836/9972/8021/7040/55746/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/293/4927/3840/8086/3837/9631/79023/23636/53371/9688/8480 36 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 36/3952 42/10654 1.0328827643498555e-10 5.051669576344892e-10 2.05964020467095e-10 83990/9156/1763/7486/5982/472/4683/84126/672/6117/83695/6118/5888/116028/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/1111/79728/5983/5883/10111/675/545/10635/5932/7156 36 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 23/3952 23/10654 1.1925109170223228e-10 5.791600222881141e-10 2.361320844159035e-10 11065/7321/8697/51529/29945/51434/29882/7314/996/983/51433/119504/7324/64682/6233/246184/8881/891/10393/7311/25906/991/7316 23 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 23/3952 23/10654 1.1925109170223228e-10 5.791600222881141e-10 2.361320844159035e-10 7321/8239/9612/4089/23327/4088/7314/6497/51592/7323/7050/5494/6233/60436/142/4087/7311/64750/54778/7316/9611/3065/6498 23 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 34/3952 39/10654 1.3029949697196413e-10 6.30613244927032e-10 2.5711032228467526e-10 83990/9156/1763/7486/5982/472/4683/84126/672/6117/83695/6118/5888/116028/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/1111/5983/5883/10111/675/545/5932/7156 34 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-194315 Signaling by Rho GTPases 234/3952 455/10654 1.388195501823267e-10 6.695151222335131e-10 2.729711915134933e-10 55839/11130/394/64837/71/6249/392/9735/7531/5526/29/51807/10971/5578/9212/347688/613/1894/7533/2810/147841/147179/348995/57122/7278/1780/23122/3688/5048/57405/8655/10094/23279/1432/2017/2491/7846/23365/79784/1060/9322/397/81027/11004/8976/1855/2885/9184/8826/10499/5518/8874/23332/25909/10726/81930/5062/55746/9411/5879/5515/26999/25/79682/1072/10403/79861/4638/25936/4659/10093/1856/10006/4771/389/5594/29127/3619/64105/7534/332/5528/6453/9828/6714/79902/3796/5519/81565/57636/999/396/91687/10376/23002/57584/58504/83540/5580/1857/128239/9055/7514/54820/6396/1535/5600/91614/801/64946/9793/10109/5586/140735/5500/10787/4221/805/220134/5170/84617/4928/4688/9743/5590/114793/5903/653361/55055/5747/80776/1783/401541/2316/7532/27237/10382/7074/10627/79172/7277/10451/79980/58480/6232/5501/6279/55288/54821/10092/9183/10163/1062/699/347733/752/22919/3895/5529/51143/998/10788/354/6654/10097/367/10383/5347/387/60/84790/84643/5058/93663/7280/4629/7529/5595/1778/5516/5905/54908/55143/1495/1499/5525/4690/1058/991/79019/4627/10928/348235/80152/10458/1063/6722/8379/1027/9459/1080/23421/55920/79023/23370/112714/1781/9824/10398/4085/5216/10552/81624/55166/4637/995/79003/391/23028/2/5527/10096/701/23380/9928/3799/57551/5296/5300/808/10095/1536/4952/10672 234 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-4090294 SUMOylation of intracellular receptors 28/3952 30/10654 1.4789796532323453e-10 7.108313973493867e-10 2.8981644634456453e-10 7068/6613/4929/9759/8856/7067/6612/5914/7421/10062/51588/2516/5465/2099/2494/9063/8554/5241/2908/9971/7329/367/6095/5468/7341/10401/6256/7376 28 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-176033 Interactions of Vpr with host cellular proteins 32/3952 36/10654 1.529735659823963e-10 7.326906315501671e-10 2.9872877857905343e-10 23165/348995/57122/23511/292/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/293/4927/8086/9631/3159/79023/23636/53371/9688/8815/8480/291 32 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-391251 Protein folding 69/3952 101/10654 1.613935779616171e-10 7.69371399057532e-10 3.1368406857864597e-10 9134/1459/2770/51807/10528/1460/7278/2775/10576/1457/7846/7411/2782/81027/10574/6468/10564/54461/10693/2773/5201/402/79861/5204/10575/6903/10681/898/10517/10471/26985/10376/2783/26190/10238/7157/2771/6904/5202/26224/84617/2781/8237/10382/7277/6774/26272/26270/347733/10383/60/84790/22948/7280/84261/10694/8841/59345/5203/112714/7203/908/6902/6905/1155/6950/3801/55294/26234 69 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 30/3952 33/10654 1.6229360685662841e-10 7.69371399057532e-10 3.1368406857864597e-10 23165/348995/57122/23511/23279/23225/9972/8021/55746/3303/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/3304/9631/79023/23636/53371/9688/8480 30 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-180746 Nuclear import of Rev protein 30/3952 33/10654 1.6229360685662841e-10 7.69371399057532e-10 3.1368406857864597e-10 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/1104/3837/9631/79023/23636/53371/9688/8480 30 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5619084 ABC transporter disorders 56/3952 77/10654 1.9688522134270398e-10 9.30182219200734e-10 3.792490121101853e-10 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/79139/91445/23198/9861/5698/5692/5713/5710/5719/10613/6233/10058/5706/335/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 56 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-388841 Costimulation by the CD28 family 52/3952 70/10654 2.4105697659093194e-10 1.1350106457112015e-9 4.6276058307197644e-10 5295/5777/5526/941/3115/3113/3117/2534/2885/2475/5518/3127/5062/5879/5515/5290/8764/5528/9020/6714/5519/29126/10000/1445/7525/3932/5781/1493/940/253260/3120/5170/3123/3122/920/64223/8503/4067/29851/5529/998/208/5058/5516/5525/3119/207/915/917/942/5527/5296 52 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 53/3952 72/10654 2.872837698665305e-10 1.3480985011642258e-9 5.496396450504745e-10 8773/5563/71/7531/51807/10971/347688/7533/2810/53632/7278/60412/5898/7846/81027/51552/5879/79861/51422/4644/7534/6810/4641/10376/11336/6844/9882/801/4218/805/84617/7532/10382/7277/5571/347733/208/5867/4012/10383/60/84790/5564/5565/7280/7529/6517/10890/4627/207/112714/8766/808 53 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 22/3952 22/10654 3.226151671700087e-10 1.503733111406517e-9 6.130941714498929e-10 3725/7531/356/7001/4001/84290/826/823/2801/993/351/6648/1020/4000/994/2309/10018/831/824/995/8851/5052 22 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8863678 Neurodegenerative Diseases 22/3952 22/10654 3.226151671700087e-10 1.503733111406517e-9 6.130941714498929e-10 3725/7531/356/7001/4001/84290/826/823/2801/993/351/6648/1020/4000/994/2309/10018/831/824/995/8851/5052 22 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2559583 Cellular Senescence 115/3952 195/10654 3.300029188279362e-10 1.5330235928160647e-9 6.250363327915145e-10 1912/3725/9134/11065/4790/7321/6045/8697/27327/80012/7295/5925/472/79813/3576/2114/1869/1911/26277/4194/1031/5928/1432/4683/23512/57332/192669/8900/51529/4001/29945/8091/51434/1030/6196/4343/6197/29882/4217/3569/7314/996/5601/5606/7027/2146/5594/898/890/5970/9261/6667/51433/5598/84733/119504/6195/7157/7324/64682/6233/2353/8726/5600/26523/5608/6015/1019/9448/246184/1029/8535/5931/7013/1051/50488/8881/6774/7867/3552/10524/5602/10393/51343/7311/25906/57634/648/23466/3456/2113/6416/23523/5595/1017/3159/7290/10111/57690/1027/192670/3490/8550/29855/7316/1026/1021/25842/23135/23112/5609/5599/10919/4193/23043 115 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 49/3952 65/10654 3.326725373468914e-10 1.5402738479161071e-9 6.279923687460617e-10 2074/5982/5431/5435/9978/5433/57654/2965/5439/2967/6117/10714/7314/6118/404672/5438/5985/2068/5984/6233/7874/8451/5434/5436/7515/8450/4331/5111/2966/6119/1161/1642/2071/51426/7311/3980/5983/5432/6917/5440/902/5430/5441/7316/5437/2033/2968/5981/1022 49 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-72086 mRNA Capping 27/3952 29/10654 3.742118395921294e-10 1.7268446684168362e-9 7.04060044415337e-10 5431/5435/5433/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/4686/5437/2968/1022 27 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5673000 RAF activation 29/3952 32/10654 4.002535844111999e-10 1.8405092464027008e-9 7.504027695537517e-10 4893/5526/817/5605/3717/5894/5518/4140/3845/3265/5515/818/5528/6714/5519/369/801/805/673/5529/816/7529/5516/815/5604/5525/5527/808/5245 29 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-191859 snRNP Assembly 42/3952 53/10654 4.0281843837755294e-10 1.8405092464027008e-9 7.504027695537517e-10 23165/6633/6606/8487/348995/57122/23511/23279/23225/79084/9972/8021/55746/10762/79902/9883/6636/10419/6396/129401/4928/6635/5903/6632/55706/7175/6637/4927/51808/8086/22916/11218/9631/79023/23636/4686/53371/9688/1207/6634/8480/6628 42 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-194441 Metabolism of non-coding RNA 42/3952 53/10654 4.0281843837755294e-10 1.8405092464027008e-9 7.504027695537517e-10 23165/6633/6606/8487/348995/57122/23511/23279/23225/79084/9972/8021/55746/10762/79902/9883/6636/10419/6396/129401/4928/6635/5903/6632/55706/7175/6637/4927/51808/8086/22916/11218/9631/79023/23636/4686/53371/9688/1207/6634/8480/6628 42 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6802952 Signaling by BRAF and RAF fusions 50/3952 67/10654 4.0661863154895653e-10 1.8517812433491825e-9 7.549985289847753e-10 4893/71/817/5908/54845/5605/5037/3717/2244/3690/408/5894/8826/4140/3845/3265/818/8805/7094/5594/7414/10533/23164/57085/6714/2335/1445/2266/2243/369/801/805/409/673/816/56829/7450/60/9444/7529/5595/4000/27044/815/5604/10018/10142/10256/5906/808 50 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 39/3952 48/10654 4.3416428687626694e-10 1.9707653414089373e-9 8.035101009268375e-10 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/6829/25920/2963/5434/5436/4331/2966/2962/8812/905/2071/5432/22916/6917/5440/902/5430/6749/5441/4686/9150/5437/6827/2968/1022/8178 39 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-168276 NS1 Mediated Effects on Host Pathways 34/3952 40/10654 5.579605052437439e-10 2.524453230565343e-9 1.02925682091937e-9 3839/23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/4927/3840/8086/3837/9631/79023/23636/53371/9688/8480 34 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6802957 Oncogenic MAPK signaling 52/3952 71/10654 5.765665708862724e-10 2.6001654771462085e-9 1.0601258206999813e-9 4893/71/817/5908/54845/5605/5037/3717/2244/3690/408/5894/8826/4140/3845/3265/4763/818/8805/7094/5594/7414/10533/23164/57085/6714/2335/1445/2266/2243/369/801/805/409/673/816/56829/7450/60/9444/7529/5595/4000/27044/815/5604/10018/10142/10256/5906/808/5245 52 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1227986 Signaling by ERBB2 40/3952 50/10654 6.269812327777716e-10 2.8183719492826043e-9 1.149091818206238e-9 5295/4893/5335/5578/2064/5753/2534/4145/2885/3845/3265/7314/1839/5290/2065/2069/9101/6714/10000/6233/7525/5580/6464/5782/10193/208/6654/7311/387/1956/2549/11140/8065/10273/207/7316/1950/3320/2066/5581 40 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5628897 TP53 Regulates Metabolic Genes 60/3952 86/10654 6.873235946378569e-10 3.0796531385547845e-9 1.2556200132942854e-9 5563/7531/10971/9997/27327/7295/7533/2810/53632/7001/192669/2475/10670/4513/4343/7296/9377/51422/7249/27244/7534/10000/2877/54541/7157/50484/9167/26523/2744/57521/83667/389541/7532/64223/5571/10128/25824/6009/8626/208/5562/4697/5564/5565/7248/7529/27161/27165/207/57690/192670/2539/54205/143686/1350/5728/23112/10542/1327/5052 60 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 54/3952 75/10654 7.707903718096099e-10 3.4425332039985467e-9 1.4035715689069897e-9 5295/374/5291/7039/3082/941/2064/2534/9965/2264/2885/8660/2252/5879/1839/5290/3667/2065/3815/2069/8074/2260/6714/2099/2248/2247/2246/5154/3932/5781/940/930/2263/4233/8503/5159/29851/9365/5293/1956/2549/2100/2254/1950/10818/2261/2255/391/2066/942/5155/4254/5296/5156 54 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6782135 Dual incision in TC-NER 49/3952 66/10654 8.270427987468652e-10 3.681930921344217e-9 1.501177549682232e-9 2074/5982/7507/5431/5435/9978/5433/57654/2965/5439/2067/2967/6117/10714/7314/6118/404672/5438/5985/2068/5984/6233/7874/8451/5434/5436/8450/4331/5111/2966/6119/1161/1642/2071/51426/7311/5983/5432/6917/5440/902/5430/5441/7316/5437/2033/2968/5981/1022 49 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-389513 CTLA4 inhibitory signaling 21/3952 21/10654 8.726448925257458e-10 3.872535960761217e-9 1.5788900359134063e-9 5526/941/2534/5518/5515/5528/6714/5519/10000/7525/3932/5781/1493/4067/5529/208/5516/5525/207/942/5527 21 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-159227 Transport of the SLBP independent Mature mRNA 30/3952 34/10654 8.874150816291754e-10 3.900694773363685e-9 1.5903707991888624e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/10482/8086/22916/9631/79023/23636/4686/53371/9688/10189/8480 30 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-187687 Signalling to ERKs 30/3952 34/10654 8.874150816291754e-10 3.900694773363685e-9 1.5903707991888624e-9 4893/5605/5898/1432/5603/2885/3845/3265/1399/5594/9261/6714/4914/5600/6300/6464/673/7867/2889/6654/7529/5595/25759/5604/57498/10818/53358/4803/1398/5906 30 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 30/3952 34/10654 8.874150816291754e-10 3.900694773363685e-9 1.5903707991888624e-9 7321/9140/9474/3093/64135/83737/7187/1540/7314/29110/9636/8887/7323/23586/7128/3661/51191/6233/55593/7706/9246/7311/7318/5094/9641/57506/7316/7322/54941/5300 30 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-3928662 EPHB-mediated forward signaling 35/3952 42/10654 9.268770568705238e-10 4.061300416382201e-9 1.6558520889800495e-9 71/1947/2051/10094/2050/2047/2534/1948/8976/3265/5879/1072/10093/5921/6453/6714/7525/10109/2904/5747/7074/1949/2049/10092/4067/998/2048/10097/387/60/5058/6383/10552/10096/10095 35 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-350054 Notch-HLH transcription pathway 26/3952 28/10654 9.444490967889722e-10 4.1123504559243965e-9 1.6766659431528364e-9 9759/9612/22938/1387/4853/9794/79885/2648/9734/55869/51564/55534/84441/10013/83933/4854/8850/3066/10046/10014/4855/4851/8841/9611/3065/3516 26 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 26/3952 28/10654 9.444490967889722e-10 4.1123504559243965e-9 1.6766659431528364e-9 7278/10576/7846/7411/81027/10574/10693/5201/5204/10575/10471/5202/84617/10382/7277/347733/10383/60/84790/22948/7280/10694/5203/7203/908/6950 26 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 28/3952 31/10654 9.840067346242613e-10 4.2578983002900275e-9 1.7360079463120269e-9 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/3837/9631/79023/23636/53371/9688/8480 28 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 28/3952 31/10654 9.840067346242613e-10 4.2578983002900275e-9 1.7360079463120269e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/9631/79023/23636/53371/9688/8480 28 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5689603 UCH proteinases 68/3952 102/10654 1.1297140808055447e-9 4.873207634282304e-9 1.9868786383569242e-9 5689/221937/5682/4738/143471/5705/5709/5695/11047/5711/7347/5683/5699/5702/7040/7345/3054/5696/5691/7314/5718/3607/5700/122706/5707/171023/23198/86/4092/9861/7046/5698/5692/5713/5710/9958/5719/6233/8607/5706/580/5714/5688/5687/5708/5704/7048/7311/60/5694/7528/5684/5720/51377/5690/5717/9491/10197/7316/10213/8314/5715/5701/5685/5686/5716/5693/5721 68 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-112382 Formation of RNA Pol II elongation complex 46/3952 61/10654 1.143614674777323e-9 4.902718466869449e-9 1.998910640124106e-9 5431/5435/5433/2965/5439/2967/11198/904/51497/4300/404672/5438/2068/1025/23168/6829/123169/25920/2963/5434/5436/9646/4331/2966/2962/4298/8812/905/2071/5432/22916/55840/6917/5440/902/6830/5430/6749/5441/4686/9150/5437/6827/2968/1022/8178 46 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-75955 RNA Polymerase II Transcription Elongation 46/3952 61/10654 1.143614674777323e-9 4.902718466869449e-9 1.998910640124106e-9 5431/5435/5433/2965/5439/2967/11198/904/51497/4300/404672/5438/2068/1025/23168/6829/123169/25920/2963/5434/5436/9646/4331/2966/2962/4298/8812/905/2071/5432/22916/55840/6917/5440/902/6830/5430/6749/5441/4686/9150/5437/6827/2968/1022/8178 46 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-157118 Signaling by NOTCH 132/3952 235/10654 1.4972124464460855e-9 6.3988556557341924e-9 2.6089078419044346e-9 8454/5689/3725/5682/892/4904/27327/3091/23385/5705/5709/9978/1869/5695/9759/9612/4609/22938/5711/1387/4088/5683/408/5699/4853/5702/192669/83737/6868/9794/4343/9787/388585/5696/5691/7314/5718/79885/2648/9734/7027/55869/5700/5707/51564/55534/3280/84441/10013/7534/83933/4854/8650/102/10320/9861/8850/5087/8788/5698/5692/5713/595/5710/3002/3066/7157/5719/6233/2324/26523/5663/142678/409/5706/10460/10046/1024/5714/6772/10014/489/5688/5687/5708/59/4855/7088/5704/23493/7311/1956/5694/4851/27161/5684/8841/2208/5720/5584/23462/207/5690/5045/57690/5717/9491/6500/51548/10197/192670/488/7316/10213/1950/9611/5715/5701/5685/5686/2033/55294/3065/861/2683/23112/5716/1385/1840/3516/5693/5721 132 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 31/3952 36/10654 1.7091250505510439e-9 7.282130966918405e-9 2.969032215681181e-9 4893/71/5908/5605/5037/2244/3690/408/5894/8826/4140/3845/3265/7094/5594/7414/6714/2335/1445/2266/2243/369/409/673/7450/60/7529/5595/5604/10256/5906 31 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 44/3952 58/10654 1.9043873281677947e-9 7.991522655060625e-9 3.2582616713444862e-009 8454/892/23385/9978/9759/9612/4609/22938/1387/6868/9794/388585/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/102/8850/3066/6233/5663/142678/10046/1024/10014/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 44 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2644603 Signaling by NOTCH1 in Cancer 44/3952 58/10654 1.9043873281677947e-9 7.991522655060625e-9 3.2582616713444862e-009 8454/892/23385/9978/9759/9612/4609/22938/1387/6868/9794/388585/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/102/8850/3066/6233/5663/142678/10046/1024/10014/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 44 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 44/3952 58/10654 1.9043873281677947e-9 7.991522655060625e-9 3.2582616713444862e-009 8454/892/23385/9978/9759/9612/4609/22938/1387/6868/9794/388585/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/102/8850/3066/6233/5663/142678/10046/1024/10014/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 44 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 44/3952 58/10654 1.9043873281677947e-9 7.991522655060625e-9 3.2582616713444862e-009 8454/892/23385/9978/9759/9612/4609/22938/1387/6868/9794/388585/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/102/8850/3066/6233/5663/142678/10046/1024/10014/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 44 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 44/3952 58/10654 1.9043873281677947e-9 7.991522655060625e-9 3.2582616713444862e-009 8454/892/23385/9978/9759/9612/4609/22938/1387/6868/9794/388585/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/102/8850/3066/6233/5663/142678/10046/1024/10014/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 44 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-167169 HIV Transcription Elongation 37/3952 46/10654 2.110481131338479e-9 8.776821231823794e-9 3.5784394852193567e-9 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/4686/9150/5437/6827/2968/1022/8178 37 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 37/3952 46/10654 2.110481131338479e-9 8.776821231823794e-9 3.5784394852193567e-9 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/4686/9150/5437/6827/2968/1022/8178 37 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 37/3952 46/10654 2.110481131338479e-9 8.776821231823794e-9 3.5784394852193567e-9 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/4686/9150/5437/6827/2968/1022/8178 37 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-180910 Vpr-mediated nuclear import of PICs 29/3952 33/10654 2.1254634216818267e-9 8.81274236631659e-9 3.593085061633379e-9 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/9631/3159/79023/23636/53371/9688/8815/8480 29 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 20/3952 20/10654 2.360047250030209e-9 9.641487147917529e-9 3.930976534106045e-9 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 20/3952 20/10654 2.360047250030209e-9 9.641487147917529e-9 3.930976534106045e-9 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-3232118 SUMOylation of transcription factors 20/3952 20/10654 2.360047250030209e-9 9.641487147917529e-9 3.930976534106045e-9 9112/6613/7022/6612/4286/6670/51588/7157/668/7158/9063/8554/7020/1029/7329/7021/3090/7341/10401/4193 20 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8876384 Listeria monocytogenes entry into host cells 20/3952 20/10654 2.360047250030209e-9 9.641487147917529e-9 3.930976534106045e-9 6456/30011/2885/7314/8027/2060/1500/6714/999/9146/6455/6233/4233/7311/79872/1499/7316/867/10254/6457 20 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 20/3952 20/10654 2.360047250030209e-9 9.641487147917529e-9 3.930976534106045e-9 22938/1387/4088/4853/9794/388585/2648/55534/3280/84441/8850/2324/10046/59/4855/23493/4851/23462/2033/3516 20 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 25/3952 27/10654 2.377230104367586e-9 9.6548906870367755e-009 3.9364413547237966e-9 5431/5435/5433/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/5440/902/5430/5441/5437/2968/1022 25 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 25/3952 27/10654 2.377230104367586e-9 9.6548906870367755e-009 3.9364413547237966e-9 5431/5435/5433/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/5440/902/5430/5441/5437/2968/1022 25 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2132295 MHC class II antigen presentation 78/3952 123/10654 2.406541949294748e-9 9.735261591363098e-9 3.969209757988213e-9 64837/51807/10484/1174/347688/1785/7278/1780/3115/8655/832/3113/10112/972/7846/3117/9632/81027/6456/11004/163/1759/3127/81930/161/79861/29127/22872/3796/10437/56992/10376/10540/3835/51128/1213/1211/9493/6396/1175/7879/140735/8907/1508/3120/1173/84617/11258/6712/1783/10382/10802/821/3123/3832/7277/160/3122/1639/26052/1062/347733/51143/9871/10383/24137/84790/84643/7280/829/1778/3119/112714/1781/10121/3799/375/10427 78 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-114452 Activation of BH3-only proteins 27/3952 30/10654 2.411036708012171e-9 9.735261591363098e-9 3.969209757988213e-9 7531/10971/7533/2810/1869/8655/7159/637/23368/7027/7534/10000/7157/140735/572/7532/5366/8626/208/7161/7529/27113/596/10018/207/5534/5599 27 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-73894 DNA Repair 176/3952 334/10654 2.728776414572558e-9 1.0986291129974734e-8 4.4792729551183414e-9 2237/4436/221120/83990/9156/2074/1763/7486/4913/56852/5982/11200/472/6613/7507/5431/5435/9978/5433/26277/10980/64421/4683/57654/2965/25898/84126/5439/10987/8900/8924/57599/2067/672/2967/6612/121642/6117/7334/10714/83695/7314/51514/6118/2176/25/5888/322/328/51588/51720/63967/404672/5531/9636/86/5438/11201/116028/890/1643/9656/51455/2177/5985/10920/29089/2068/7157/5984/4595/4255/6233/7158/6047/55247/8607/7874/5884/5810/5886/8451/8554/8467/80010/124739/3838/5434/5436/2956/7515/7013/4292/7706/580/11073/5591/8450/4331/641/5111/2966/6119/83932/3364/10524/144715/1161/1642/142/1111/2071/55215/1069/7329/9246/79728/51426/2873/7311/7318/4968/3980/60/8533/5983/10038/2547/5432/51138/7528/9318/1017/6917/5440/2178/902/5883/5430/10111/7320/7520/675/51548/545/5441/7336/54778/7316/6996/64708/8314/79008/9100/10635/7415/5395/7341/5437/10401/2033/7398/2968/5932/9025/2189/79184/7156/5887/5599/5981/1022/8178/50813/5980/7508 176 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8986944 Transcriptional Regulation by MECP2 46/3952 62/10654 2.8395489092203352e-9 1.1399229580656201e-8 4.6476340528157605e-9 627/2290/5770/817/9212/27327/6657/28996/9612/4988/192669/4204/3654/4343/814/818/6446/54487/4208/3066/26523/801/805/2904/3930/4233/5566/1392/816/25942/27161/815/8841/5468/57690/192670/114787/9611/2874/5775/3064/5728/3065/23112/1385/808 46 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1980143 Signaling by NOTCH1 52/3952 73/10654 2.9570523004991015e-9 1.1826147577543555e-8 4.821694817716974e-9 8454/892/3091/23385/9978/9759/9612/4609/22938/1387/408/83737/6868/9794/388585/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/8650/102/8850/8788/3066/6233/5663/142678/409/10046/1024/10014/7088/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/1840/3516 52 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5689896 Ovarian tumor domain proteases 32/3952 38/10654 2.962922503229055e-9 1.1826147577543555e-8 4.821694817716974e-9 7321/324/64135/7187/7314/8737/8767/55611/8517/80124/983/2099/23586/7128/7157/6233/55593/10318/7706/79155/79589/64127/7189/7311/387/56957/10392/57506/7316/7415/5728/78990 32 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 30/3952 35/10654 3.997271271702665e-9 1.5863456561128574e-8 6.467765245642208e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/10482/8086/22916/9631/79023/23636/4686/53371/9688/10189/8480 30 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 30/3952 35/10654 3.997271271702665e-9 1.5863456561128574e-8 6.467765245642208e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/983/79902/9883/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/9631/140609/79023/23636/53371/9688/8480 30 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8939211 ESR-mediated signaling 125/3952 223/10654 4.834873645154346e-9 1.9132876048773183e-8 7.800755798749554e-9 5295/374/3725/4893/857/2770/7039/27327/10274/5431/5435/5433/5469/4609/1387/8312/2782/5439/192669/10499/1386/4343/3845/904/7392/3265/2773/6387/1839/5290/4316/5594/2069/10681/5481/5438/4313/865/1655/6667/6714/2099/2494/8850/10000/595/2783/2771/7514/1025/2353/26523/801/2957/805/5170/2963/3838/5434/5590/6464/5241/5747/5436/3315/4318/200845/5885/2962/8503/10524/8243/4602/208/3326/6908/1956/3169/5432/3480/10728/5595/7528/3727/27161/2354/596/5440/4435/2309/9687/59345/5430/207/5451/2625/57690/6722/1027/5441/10735/192670/2100/1950/4314/7391/2958/5437/3320/2033/4846/9126/3065/2066/861/23028/23112/10498/1385/5296/808/3276/8202/8648/2288 125 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9619483 Activation of AMPK downstream of NMDARs 26/3952 29/10654 5.88650532582827e-9 2.3228283799930304e-8 9.470513951242851e-9 5563/51807/347688/53632/7278/7846/81027/79861/51422/10376/801/805/84617/10382/7277/5571/347733/5562/10383/84790/5564/5565/7280/112714/4137/808 26 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2173788 Downregulation of TGF-beta receptor signaling 24/3952 26/10654 5.9664102939697594e-9 2.341057598396609e-8 9.544837163710174e-9 25805/9372/23327/4088/5499/7040/7314/4092/11171/7046/9958/6233/7514/5500/5501/23645/4087/7048/7311/57154/51377/10273/64750/7316 24 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-912694 Regulation of IFNA signaling 24/3952 26/10654 5.9664102939697594e-9 2.341057598396609e-8 9.544837163710174e-9 3443/5777/5770/9021/11274/3445/3444/3451/3448/3439/3452/6773/7297/5781/3446/3455/6772/8651/3440/3454/3716/3456/3441/3449 24 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-442755 Activation of NMDA receptors and postsynaptic events 62/3952 93/10654 6.1115827185789494e-9 2.391264336931313e-8 9.749537442833135e-9 5563/4893/51807/817/347688/53632/7278/7846/81027/1739/6196/8874/6197/3845/3265/814/5879/818/57554/79861/5567/5594/51422/5573/6714/10376/6195/801/805/5170/84617/3838/8573/2904/10382/5568/7277/5566/5571/27330/347733/816/5577/5562/10383/84790/5564/5565/7280/5595/815/28964/5575/112714/5576/4137/2066/9647/88/1385/808/8536 62 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-202733 Cell surface interactions at the vascular wall 84/3952 137/10654 6.289967061266176e-9 2.441911198396492e-8 9.956032168067244e-9 5295/5777/4893/857/5335/6385/960/5291/7056/5175/3688/972/2534/3690/2885/4072/5676/6382/5673/7040/3845/4282/3265/3655/6693/5290/5680/6401/4312/50848/3683/6714/965/8797/914/2335/5671/5478/7525/3685/3932/5781/5672/2147/6464/483/3684/7010/1048/2888/1277/338/5670/4267/6403/4067/140885/5624/6402/6654/8795/5669/3676/9123/2817/8793/5675/1525/6383/5196/2621/83953/682/5678/6520/440533/5296/3687/1278/481/3689/5627/284/9046 84 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-390466 Chaperonin-mediated protein folding 63/3952 95/10654 6.339216796312161e-9 2.441911198396492e-8 9.956032168067244e-9 9134/1459/2770/51807/10528/1460/7278/2775/10576/1457/7846/7411/2782/81027/10574/6468/10564/54461/10693/2773/5201/79861/5204/10575/10681/898/10517/10471/26985/10376/2783/26190/10238/7157/2771/5202/26224/84617/2781/8237/10382/7277/6774/26272/26270/347733/10383/60/84790/22948/7280/84261/10694/8841/59345/5203/112714/7203/908/6950/3801/55294/26234 63 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-73762 RNA Polymerase I Transcription Initiation 37/3952 47/10654 6.3688509083348615e-9 2.441911198396492e-8 9.956032168067244e-9 2074/9112/5435/5928/2965/1107/2967/2648/404672/8850/57459/2068/3066/5434/9015/79101/9219/5931/4331/9013/1108/2966/54815/2071/57504/6908/53615/5440/902/9014/5441/51082/5437/3065/2968/1022/10919 37 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 19/3952 19/10654 6.3816685746431e-9 2.441911198396492e-8 9.956032168067244e-9 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 19/3952 19/10654 6.3816685746431e-9 2.441911198396492e-8 9.956032168067244e-9 11065/7321/8697/51529/29945/51434/29882/996/51433/119504/7324/64682/246184/8881/10393/51343/25906/991/8556 19 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-176412 Phosphorylation of the APC/C 19/3952 19/10654 6.3816685746431e-9 2.441911198396492e-8 9.956032168067244e-9 11065/7321/8697/51529/29945/51434/29882/996/983/51433/119504/7324/64682/246184/8881/891/10393/25906/5347 19 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 19/3952 19/10654 6.3816685746431e-9 2.441911198396492e-8 9.956032168067244e-9 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8851708 Signaling by FGFR2 IIIa TM 19/3952 19/10654 6.3816685746431e-9 2.441911198396492e-8 9.956032168067244e-9 5431/5435/5433/5439/5438/2247/2246/2963/5434/5436/2263/2962/5432/22916/5440/5430/5441/4686/5437 19 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1474244 Extracellular matrix organization 160/3952 301/10654 6.520052265799926e-9 2.4880089552736535e-8 1.0143979522846619e-8 8174/871/6385/960/3696/7042/5175/5578/11131/23385/92291/3383/54829/1280/1289/7448/6696/3688/176/4054/3693/825/6650/2192/3910/1303/650/836/2244/1605/3690/3694/2200/3385/87/6868/8985/4325/6382/7040/30008/84290/7043/63827/5054/3655/50859/826/3918/7373/633/4238/4316/6678/5340/4320/26254/7412/10753/823/1284/284217/2006/4312/50848/3683/4313/3672/102/5339/388743/4148/5033/999/2247/827/2335/3909/1288/726/4326/2266/3685/1292/5154/7076/2243/3791/3691/5663/1291/1508/7077/8573/7276/1308/351/655/4052/8754/3684/3384/4318/11132/1277/3912/147968/3695/5351/5802/23473/4322/8751/3913/652/4060/7450/222663/4321/5650/2331/5479/3676/4319/3371/1282/4239/1991/5045/1634/79709/6383/831/649/4314/667/3915/1462/824/1281/3673/682/1758/440854/3914/2/8425/27302/780/5155/8516/3687/80781/7057/1278/3689/4323/4921/5034/3682 160 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8848021 Signaling by PTK6 41/3952 54/10654 6.557603927816328e-9 2.4886644414581638e-8 1.0146652036713215e-8 4893/5770/9021/27043/3091/2064/5753/9564/3845/3265/5829/7314/5879/120892/1839/2065/2069/898/5921/6421/595/6233/1019/10657/6774/2908/7311/2034/387/1956/1017/207/55620/1027/10457/7316/1950/867/2066/1398/9844 41 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 41/3952 54/10654 6.557603927816328e-9 2.4886644414581638e-8 1.0146652036713215e-8 4893/5770/9021/27043/3091/2064/5753/9564/3845/3265/5829/7314/5879/120892/1839/2065/2069/898/5921/6421/595/6233/1019/10657/6774/2908/7311/2034/387/1956/1017/207/55620/1027/10457/7316/1950/867/2066/1398/9844 41 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9009391 Extra-nuclear estrogen signaling 53/3952 77/10654 1.4356240455831932e-8 5.4334653932290336e-8 2.2153039911767046e-8 5295/374/4893/857/2770/7039/2782/3845/3265/2773/1839/5290/4316/5594/2069/10681/4313/6714/2099/10000/595/2783/2771/7514/2353/801/805/5170/5590/6464/5747/3315/4318/8503/208/1956/3480/5595/596/2309/59345/207/6722/1027/2100/1950/4314/3320/4846/1385/5296/808/3276 53 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 106/3952 185/10654 1.46395967891358e-8 5.525652157638485e-8 2.2528898948956127e-8 6158/5393/6138/6227/6206/6234/6191/6128/6132/6129/6176/10528/27043/6224/6146/6154/6202/6169/55272/6175/6218/6173/6167/23481/6192/6156/117246/6143/6139/26168/11340/3921/6208/6170/10813/6203/6147/6222/1454/51602/6134/6155/6231/6142/23521/6207/10969/6233/6188/1453/4691/23016/6122/6230/2091/8602/6194/6166/10436/6136/6125/6232/6160/6193/10200/6210/6229/6205/140801/6235/6181/7311/6223/25873/26354/9045/6187/6168/6157/6137/79050/6144/9349/4736/51121/6159/25879/6217/6152/51065/6141/6164/6209/11224/6165/6130/6204/6228/6124/83732/6189/6135/6201/54512/6133/9188 106 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1643713 Signaling by EGFR in Cancer 23/3952 25/10654 1.492836351481486e-8 5.589082728322868e-8 2.2787514742432672e-8 5295/374/4893/5335/7039/2885/3845/3265/7314/1839/5290/2069/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 23 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 23/3952 25/10654 1.492836351481486e-8 5.589082728322868e-8 2.2787514742432672e-8 51807/7278/10576/7846/81027/10574/10693/79861/10575/10376/84617/10382/7277/347733/10383/84790/22948/7280/10694/112714/7203/908/6950 23 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9006115 Signaling by NTRK2 (TRKB) 23/3952 25/10654 1.492836351481486e-8 5.589082728322868e-8 2.2787514742432672e-8 5295/627/4893/5335/2534/2885/3845/3265/5879/5290/6714/4909/5781/4908/6464/2904/7074/6654/2549/1020/4915/10818/8851 23 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-195721 Signaling by WNT 172/3952 331/10654 1.570139713281579e-8 5.862699090720734e-8 2.3903089013737678e-8 8454/27123/9070/5689/857/5682/5331/1459/5526/1452/5578/1212/5929/5582/27327/1460/143471/5705/6657/2775/8452/5530/50964/5709/9978/5695/1457/9559/4609/5711/1387/5683/324/5699/8312/2782/5702/192669/1855/6932/163/5518/4343/3845/6659/80351/5696/5691/7314/5879/5515/5718/51176/8945/7476/161/6662/51701/5700/122706/5707/1856/1454/8322/23198/10681/9101/7471/7534/5528/51699/83439/59349/9861/81847/5519/2932/5698/5692/5713/2783/23002/5710/8313/5719/6233/7474/1857/7514/1213/3710/1211/331/8607/1175/26523/801/4221/805/123169/1173/144165/6597/864/4772/409/5706/160/8658/5714/6934/10524/5688/5687/23236/5708/5529/7088/208/57680/5704/7311/387/5694/5516/57154/27161/815/5684/8295/5720/7015/6885/1487/1499/5525/59345/139285/207/5690/57690/5717/9491/50855/6500/3708/10197/192670/64750/7316/10213/64321/5216/5715/5701/1455/5685/5686/2033/54894/5534/3065/23112/23513/5527/5716/23072/808/5693/5721/6259/5592 172 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5675482 Regulation of necroptotic cell death 18/3952 18/10654 1.725354015249207e-8 6.424977820860988e-8 2.61955823396098e-8 356/7314/8737/841/8797/6233/8772/331/8717/8743/330/8837/7311/8795/7186/355/7316/329 18 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-373760 L1CAM interactions 74/3952 119/10654 2.1153410669036725e-8 7.85617310676257e-8 3.2030776639295694e-8 9252/6711/71/7430/1459/51807/347688/1785/1460/7278/8829/3688/1457/5605/7846/3690/81027/6456/1739/6709/5962/163/6196/1759/6197/8986/3312/100133941/5879/161/79861/5594/284217/2260/3672/8650/6714/10376/6195/214/3685/1213/1211/1175/1173/84617/6712/10382/7277/4478/160/3912/26052/6710/27330/347733/6386/2048/10383/24137/1956/60/84790/5058/7280/5595/5604/10048/11313/112714/3915/3673/287/288 74 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1433557 Signaling by SCF-KIT 34/3952 43/10654 2.175629875863349e-8 8.037100791420722e-8 3.27684454987257e-8 5295/5777/4893/5578/6776/3717/2534/2885/3845/3265/5879/5290/3815/9306/6714/7525/3932/6777/5781/10019/2241/4318/6774/6772/8651/8503/4067/1111/6654/867/4254/5296/2887/2242 34 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5655253 Signaling by FGFR2 in disease 34/3952 43/10654 2.175629875863349e-8 8.037100791420722e-8 3.27684454987257e-8 5295/4893/5335/5431/5435/5433/5439/2885/2252/3845/3265/5290/8074/5438/2248/2247/2246/2963/5434/5436/2263/2962/6654/2549/5432/22916/5440/5430/5441/2254/4686/10818/5437/2255 34 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-111465 Apoptotic cleavage of cellular proteins 31/3952 38/10654 2.3685277397841686e-8 8.703399551746588e-8 3.5485043831909856e-8 2339/660/836/324/9414/4001/6709/840/2934/63967/841/100506658/7082/5339/28988/10134/999/5580/839/5747/118/1829/8428/1832/4000/51765/1499/329/4137/7431/6304 31 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 31/3952 38/10654 2.3685277397841686e-8 8.703399551746588e-8 3.5485043831909856e-8 5908/1265/3313/6175/5898/3181/4001/4282/5062/1072/6627/9049/27250/9987/3185/3458/5478/302/552900/6775/4478/998/6648/2939/3586/829/5055/6647/6950/375/5721 31 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2980766 Nuclear Envelope Breakdown 39/3952 52/10654 2.7884039551511033e-8 1.0219242991305759e-7 4.166536114071084e-8 23165/5578/348995/57122/23511/23279/23225/4001/9972/8021/55746/10762/983/79902/9883/7444/2010/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/5347/7112/4000/9631/140609/79023/23636/7443/53371/9688/8815/8480 39 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6804758 Regulation of TP53 Activity through Acetylation 26/3952 30/10654 2.847705134163264e-8 1.0409111661454669e-7 4.243948371689297e-8 64769/84289/29117/5928/1107/5371/23774/3622/27154/57459/10000/7994/3066/7157/5608/7862/9219/5931/1108/54815/208/53615/207/2033/3065/5300 26 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 20/3952 21/10654 3.210809440011947e-8 1.1674906576378518e-7 4.760031630549539e-8 25904/55571/55835/57472/85456/29883/1263/7832/10769/7157/5325/4869/4850/246175/4848/23019/4849/9337/28984/995 20 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6807004 Negative regulation of MET activity 20/3952 21/10654 3.210809440011947e-8 1.1674906576378518e-7 4.760031630549539e-8 5770/3082/6456/30011/2885/7314/8027/2060/9101/9146/6455/6233/4233/5795/5771/7311/7316/867/10254/6457 20 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-912526 Interleukin receptor SHC signaling 24/3952 27/10654 3.4679851810787275e-8 1.2577105526157577e-7 5.127871450928558e-8 5295/5777/1437/5291/3558/3717/3563/2885/5290/1439/3718/3567/3562/6464/1438/8503/3636/6654/3716/5293/3561/3560/5296/3559 24 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-450302 activated TAK1 mediates p38 MAPK activation 22/3952 24/10654 3.7227618660263484e-8 1.3465927687267182e-7 5.490257357242806e-8 1432/3654/7334/7314/257397/5606/8767/23118/8517/9261/10454/6233/5600/5608/7867/64127/7189/7311/6885/10392/7316/7335 22 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-186797 Signaling by PDGF 42/3952 58/10654 4.5856988850901493e-8 1.6544248704909654e-7 6.745334245190706e-8 5295/4893/5335/5291/1280/1289/6696/6776/5327/2885/8440/9564/3845/3265/1399/5290/5340/1284/5921/6778/6714/1292/5154/6777/5781/1291/5782/6774/6772/2889/5159/7058/6654/1282/4690/5045/1281/1398/5155/5296/7057/5156 42 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8934593 Regulation of RUNX1 Expression and Activity 17/3952 17/10654 4.6639366353763267e-8 1.6782922244916368e-7 6.842644968182339e-8 27327/192669/5371/4343/865/6714/595/896/26523/5781/27161/894/57690/192670/1021/861/23112 17 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-176187 Activation of ATR in response to replication stress 30/3952 37/10654 5.254287654571455e-8 1.8858412279585922e-7 7.688852871370715e-8 5982/4174/84515/4998/990/84126/55388/6117/6118/23594/63967/993/5985/5984/5884/5810/4172/8318/4173/6119/3364/144715/1111/5983/4176/1017/5883/545/4171/995 30 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-3928665 EPH-ephrin mediated repulsion of cells 38/3952 51/10654 5.697974019538362e-8 2.0398159569945323e-7 8.316630554833531e-8 71/2042/1947/1212/23385/2051/2050/2047/2534/1948/163/1759/5879/161/4313/102/6714/7525/1942/1213/1211/1175/5663/1173/7074/1949/10451/4318/160/2049/8218/4067/2044/2048/60/1946/1944/1969 38 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-933541 TRAF6 mediated IRF7 activation 25/3952 29/10654 6.700811251144647e-8 2.386519699446132e-7 9.730192855913147e-8 3443/1387/64135/3445/29110/3444/23586/3451/3448/3661/3439/10010/3452/3446/3665/7706/3440/7189/9641/3456/3441/7186/57506/3449/2033 25 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 25/3952 29/10654 6.700811251144647e-8 2.386519699446132e-7 9.730192855913147e-8 2308/84676/4089/4088/3630/56729/2538/847/3484/5443/3066/5105/4303/23410/4287/2908/4852/6648/4087/25942/2309/6720/114907/3065/10891 25 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 19/3952 20/10654 8.279247374228818e-8 2.918749899188789e-7 1.1900173890823149e-7 7321/7334/3551/7314/11035/8737/8517/7323/6233/330/7098/7189/7311/1147/7316/7335/7322/329/148022 19 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5213460 RIPK1-mediated regulated necrosis 19/3952 20/10654 8.279247374228818e-8 2.918749899188789e-7 1.1900173890823149e-7 356/7314/11035/8737/841/8797/6233/8772/331/8717/8743/330/8837/7311/8795/7186/355/7316/329 19 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5218859 Regulated Necrosis 19/3952 20/10654 8.279247374228818e-8 2.918749899188789e-7 1.1900173890823149e-7 356/7314/11035/8737/841/8797/6233/8772/331/8717/8743/330/8837/7311/8795/7186/355/7316/329 19 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 19/3952 20/10654 8.279247374228818e-8 2.918749899188789e-7 1.1900173890823149e-7 472/1387/51499/7159/637/27166/23368/7157/63970/55240/5366/84883/147923/94241/8626/7161/665/27113/581 19 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6803529 FGFR2 alternative splicing 23/3952 26/10654 8.363667154129378e-8 2.941046500528027e-7 1.199108042350861e-7 54845/5431/5435/5433/5439/7073/5438/3185/4670/5725/2963/5434/5436/2962/5432/22916/5440/5430/3178/5441/4686/5437/3187 23 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 21/3952 23/10654 9.250303424911505e-8 3.2364411730987606e-7 1.3195448077959408e-7 5431/5435/5433/5439/51497/5438/6829/25920/2963/5434/5436/2962/5432/22916/5440/5430/5441/4686/9150/5437/6827 21 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 21/3952 23/10654 9.250303424911505e-8 3.2364411730987606e-7 1.3195448077959408e-7 3654/7334/7314/257397/5601/8767/23118/8517/10454/6233/64127/5602/7189/7311/6416/6885/10392/7316/7335/5609/5599 21 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-73893 DNA Damage Bypass 36/3952 48/10654 9.630298949232893e-8 3.3609259398202233e-7 1.3702990834930698e-7 56852/5982/9978/25898/57599/6117/10714/7314/51514/6118/9636/11201/51455/5985/5984/6233/8451/124739/7706/8450/5111/6119/83932/1642/9246/51426/7311/7318/5983/7320/7316/9100/7415/7398/5981/5980 36 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 32/3952 41/10654 1.0011344570724695e-7 3.485152282891379e-7 1.4209479960558993e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/10482/8086/22916/9631/29894/79023/23636/4686/53371/9688/10189/8480/55339 32 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 55/3952 84/10654 1.1184185327948003e-7 3.8837083551299443e-7 1.5834451859042173e-7 7124/1052/4790/9441/892/5469/9612/1387/84246/55588/10499/23054/7040/9282/51129/7471/3952/5465/5970/896/9370/1879/9412/54797/5105/1019/9440/6721/1051/9442/1050/1024/9314/10001/9443/9477/51586/6517/8841/5468/29079/90390/6720/6837/688/9611/2033/9967/6256/51003/10498/112950/8202/8648/10891 55 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 26/3952 31/10654 1.1393157537054377e-7 3.911969532260149e-7 1.5949676847076354e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/9631/79023/23636/53371/9688/8480 26 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-182971 EGFR downregulation 26/3952 31/10654 1.1393157537054377e-7 3.911969532260149e-7 1.5949676847076354e-7 374/7039/6456/30011/2885/8874/10252/7314/1839/8027/2060/2069/9146/6455/6233/29924/5782/998/7311/1956/58513/7316/1950/867/10254/6457 26 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 26/3952 31/10654 1.1393157537054377e-7 3.911969532260149e-7 1.5949676847076354e-7 3725/9252/1848/1432/6196/5518/1386/6197/51231/5515/5601/5594/5528/9261/5519/5598/4208/6195/2353/5600/5602/5595/5516/466/1385/5599 26 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 26/3952 31/10654 1.1393157537054377e-7 3.911969532260149e-7 1.5949676847076354e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/9631/79023/23636/53371/9688/8480 26 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 56/3952 86/10654 1.1406390644819008e-7 3.911969532260149e-7 1.5949676847076354e-7 5295/5335/71/5291/2268/147179/10094/2534/8976/2885/5879/26999/25/1072/5290/10093/10006/5336/4771/5594/4644/8398/4641/6714/7525/5580/3710/10109/10787/5747/2209/10451/6850/10092/10163/4067/998/3326/10097/60/5058/5595/4690/4627/10458/3708/3055/10552/917/3320/1398/10096/9844/5296/5581/10095 56 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8868773 rRNA processing in the nucleus and cytosol 108/3952 195/10654 1.2434565496256174e-7 4.254091496132962e-7 1.734455856102106e-7 6158/5393/6138/6227/6206/6234/6191/6128/6132/6129/55226/6176/10528/27043/6224/6146/6154/6202/6169/55272/6175/6218/6173/6167/23481/6192/6156/117246/6143/6139/26168/11340/3921/6208/6170/10813/6203/6147/6222/1454/51602/6134/6155/6231/6142/23521/6207/10969/6233/6188/1453/4691/23016/6122/6230/2091/8602/6194/6166/10436/6136/6125/6232/6160/6193/10200/6210/6229/6205/140801/6235/6181/7311/6223/25873/26354/9045/6187/6168/6157/6137/79050/6144/9349/4736/51121/6159/25879/6217/6152/51065/6141/6164/6209/11224/6165/6130/6204/1736/6228/6124/83732/6189/6135/6201/54512/6133/9188 108 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-193639 p75NTR signals via NF-kB 16/3952 16/10654 1.260542630262534e-7 4.280913724779119e-7 1.7453916743823015e-7 4790/8878/4792/3654/3551/7314/8767/5970/6233/7189/7311/4804/5584/4615/7316/4803 16 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 16/3952 16/10654 1.260542630262534e-7 4.280913724779119e-7 1.7453916743823015e-7 7040/7314/50848/7046/2280/6233/57530/5590/7048/7311/387/57154/50855/23370/7316/56288 16 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9614657 FOXO-mediated transcription of cell death genes 16/3952 16/10654 1.260542630262534e-7 4.280913724779119e-7 1.7453916743823015e-7 2308/65018/356/1387/4801/604/4303/4800/10370/6794/27113/2309/10018/4802/1649/2033 16 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5655302 Signaling by FGFR1 in disease 30/3952 38/10654 1.6075887335023643e-7 5.432945865778063e-7 2.2150921721712696e-7 5295/4893/11052/5335/9530/613/6776/11064/2885/3845/3265/7750/8805/26127/5290/8074/2260/399687/2247/2246/6777/1523/9208/6774/6772/6654/11160/2549/2254/10818 30 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 30/3952 38/10654 1.6075887335023643e-7 5.432945865778063e-7 2.2150921721712696e-7 1912/1459/6045/80012/1460/28996/1457/1911/6603/10138/57332/57492/86/865/84733/8289/6602/23429/6015/6595/6597/8535/6599/648/6601/23466/6598/2033/6605/861 30 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2559585 Oncogene Induced Senescence 27/3952 33/10654 1.76317932130106e-7 5.929917862680805e-7 2.4177149862621904e-7 27327/5925/2114/1869/4194/1031/192669/1030/4343/7314/7027/5594/6667/7157/6233/26523/1019/1029/7311/2113/5595/57690/192670/7316/1021/23112/4193 27 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 27/3952 33/10654 1.76317932130106e-7 5.929917862680805e-7 2.4177149862621904e-7 4790/4792/3654/7334/3551/7314/257397/8767/23118/8517/5970/10454/6233/4791/351/64127/7189/7311/1147/6885/10392/7316/7335/4793/3146/6288/6285 27 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6807878 COPI-mediated anterograde transport 63/3952 101/10654 1.9959717772923178e-7 6.671037684943649e-7 2.7198804702358256e-7 6811/6711/11014/51807/347688/5861/7278/1780/8655/832/7846/51226/3630/81027/6709/10652/54732/79861/2801/1315/8615/11316/8729/23423/10376/1314/10540/378/26958/140735/84364/22820/84617/11258/6712/1783/10382/7277/966/1639/10282/6710/81876/347733/51143/10383/84790/7280/829/1778/51014/112714/1781/10121/2804/10972/4905/9276/287/375/288/22818/372 63 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 22/3952 25/10654 2.007554897268859e-7 6.671037684943649e-7 2.7198804702358256e-7 2308/2475/7249/2932/10000/2931/253260/5170/572/4303/6199/64223/208/1147/2309/842/207/1027/1026/3164/1385/4193 22 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 22/3952 25/10654 2.007554897268859e-7 6.671037684943649e-7 2.7198804702358256e-7 51400/5520/8900/5518/7465/5515/993/890/983/5519/7514/2305/9133/891/4331/5347/5516/1017/994/902/995/1022 22 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8854691 Interleukin-20 family signaling 22/3952 25/10654 2.007554897268859e-7 6.671037684943649e-7 2.7198804702358256e-7 11009/6776/3717/282618/50604/3588/55801/3718/6777/6773/7297/5781/6775/50616/53833/6774/6772/29949/163702/3716/58985/53832 22 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9006335 Signaling by Erythropoietin 22/3952 25/10654 2.007554897268859e-7 6.671037684943649e-7 2.7198804702358256e-7 5295/4893/5335/5291/6776/3717/2885/2056/8660/3845/3265/1399/5290/5336/2057/6777/6464/2889/4067/6654/5293/2549 22 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5674135 MAP2K and MAPK activation 31/3952 40/10654 2.127108378234883e-7 7.009092427990349e-7 2.857710375702935e-7 4893/71/5908/5605/5037/2244/3690/408/5894/8826/4140/3845/3265/7094/5594/7414/6714/2335/1445/2266/2243/369/409/673/7450/60/7529/5595/5604/10256/5906 31 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5675221 Negative regulation of MAPK pathway 31/3952 40/10654 2.127108378234883e-7 7.009092427990349e-7 2.857710375702935e-7 4893/1844/1848/5526/5605/5037/5894/1847/5518/4140/3845/3265/7314/5515/5594/5528/5519/6233/1843/369/11221/673/5529/7311/7529/5595/5516/5604/5525/7316/5527 31 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-3928664 Ephrin signaling 18/3952 19/10654 2.1294722855377446e-7 7.009092427990349e-7 2.857710375702935e-7 1947/2051/2050/2047/2534/1948/8440/8874/5062/5879/6714/1949/10627/2049/6386/2048/5058/28964 18 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6804760 Regulation of TP53 Activity through Methylation 18/3952 19/10654 2.1294722855377446e-7 7.009092427990349e-7 2.857710375702935e-7 133383/11200/472/79813/4194/56950/7314/7157/6233/10419/26013/7311/7316/2033/91875/133746/10919/4193 18 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-389977 Post-chaperonin tubulin folding pathway 20/3952 22/10654 2.2895634715135213e-7 7.500480334745946e-7 3.058056473868606e-7 51807/7278/7846/81027/402/79861/6903/10376/6904/84617/10382/7277/347733/10383/84790/7280/112714/6902/6905/1155 20 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-912631 Regulation of signaling by CBL 20/3952 22/10654 2.2895634715135213e-7 7.500480334745946e-7 3.058056473868606e-7 5295/5291/2534/2885/1399/7314/5290/6233/7525/6850/8503/2889/4067/7311/5293/7316/3055/867/1398/5296 20 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 32/3952 42/10654 2.706709634119402e-7 8.831733351786103e-7 3.6008279665499026e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/10482/8086/22916/9631/29894/79023/23636/4686/53371/9688/10189/8480/55339 32 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 37/3952 51/10654 2.708652561454917e-7 8.831733351786103e-7 3.6008279665499026e-7 51807/347688/7278/1780/5048/8655/832/636/7846/2590/81027/79861/23299/8398/10376/10540/140735/84617/11258/1783/10382/7277/1639/347733/51143/10383/84790/5049/7280/829/22931/1778/5321/5050/112714/1781/10121 37 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 129/3952 244/10654 2.843211418711658e-7 9.24876032925174e-7 3.770856016928072e-7 23165/6633/8683/6431/4904/51639/51585/23450/348995/57122/5431/9092/23511/5435/6625/5433/3190/56339/23279/22938/988/23225/3181/5439/1660/9410/6638/57721/9972/8021/3312/10291/55746/7919/6432/8563/6627/11051/8106/55749/5438/10762/11338/1655/9343/3185/6626/24144/79902/9883/10236/10250/4670/26097/55660/2521/3191/6636/23524/10914/57187/6396/129401/3188/56259/5725/1994/7536/4928/2963/6635/5434/5903/220988/6632/55706/7175/24148/5436/10523/6428/27258/6637/5093/4927/2962/23658/10482/8086/5094/6426/5432/22916/11100/10921/22827/23451/5440/9631/5430/3184/25804/29894/51503/3178/79023/5441/23636/3183/10594/4686/10713/53371/7307/9688/5437/10189/10949/57794/27316/3187/6634/51593/9775/3192/8480/10992/55339/6628 129 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-199977 ER to Golgi Anterograde Transport 88/3952 154/10654 2.863034417509519e-7 9.291483191403556e-7 3.7882747580426007e-7 6811/374/6711/11014/126003/2153/51807/10484/7039/347688/5861/7278/1780/8655/832/3998/7846/51226/375056/9632/3630/81027/6709/10652/54732/79861/10342/4253/2801/22872/1315/81562/8615/11316/8729/23423/10376/1314/10540/51128/6399/378/6396/1453/26958/140735/84364/22820/84617/11258/6712/1783/10382/10802/2157/7277/966/11196/1639/10282/6710/81876/347733/51143/5537/9871/10383/84790/7280/829/1778/9919/55291/51014/112714/1781/10121/2804/5265/10972/4905/9276/287/375/288/10427/22818/372 88 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1170546 Prolactin receptor signaling 15/3952 15/10654 3.4063787257716817e-7 1.0802420205700606e-6 4.4043060669674723e-007 8454/6776/9978/3717/5618/8945/2690/5617/6777/5781/1442/2689/6500/25970/2688 15 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 15/3952 15/10654 3.4063787257716817e-7 1.0802420205700606e-6 4.4043060669674723e-007 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 15/3952 15/10654 3.4063787257716817e-7 1.0802420205700606e-6 4.4043060669674723e-007 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 15/3952 15/10654 3.4063787257716817e-7 1.0802420205700606e-6 4.4043060669674723e-007 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 15/3952 15/10654 3.4063787257716817e-7 1.0802420205700606e-6 4.4043060669674723e-007 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 15/3952 15/10654 3.4063787257716817e-7 1.0802420205700606e-6 4.4043060669674723e-007 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 15/3952 15/10654 3.4063787257716817e-7 1.0802420205700606e-6 4.4043060669674723e-007 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5637810 Constitutive Signaling by EGFRvIII 15/3952 15/10654 3.4063787257716817e-7 1.0802420205700606e-6 4.4043060669674723e-007 5295/4893/5335/2885/3845/3265/5290/6464/6654/1956/2549/11140/1950/867/3320 15 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5637812 Signaling by EGFRvIII in Cancer 15/3952 15/10654 3.4063787257716817e-7 1.0802420205700606e-6 4.4043060669674723e-007 5295/4893/5335/2885/3845/3265/5290/6464/6654/1956/2549/11140/1950/867/3320 15 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 15/3952 15/10654 3.4063787257716817e-7 1.0802420205700606e-6 4.4043060669674723e-007 6456/30011/2885/7314/8027/2060/9146/6455/6233/4233/7311/7316/867/10254/6457 15 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-3000170 Syndecan interactions 23/3952 27/10654 3.651383849917059e-7 1.1553011771149874e-6 4.710333320358178e-7 6385/5578/1289/7448/3688/3693/3690/87/6382/7040/3655/2247/2335/3685/3691/8573/1277/3371/6383/1281/3673/7057/1278 23 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8941326 RUNX2 regulates bone development 26/3952 32/10654 3.9227349651758365e-7 1.2383361060520993e-6 5.048878974317226e-7 5925/9759/10413/4089/3549/25/5594/3280/10013/2737/865/6714/7525/4091/1277/2736/23493/367/860/5595/8841/23462/4086/4094/25925/25937 26 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-3000171 Non-integrin membrane-ECM interactions 41/3952 59/10654 4.174210918005334e-7 1.3147344592084828e-6 5.360366329840959e-7 6385/5578/1280/1289/7448/3688/3693/3910/1605/3690/87/6382/7040/3655/3918/1284/284217/2247/2335/3909/1288/3685/5154/3691/8573/7276/1277/3912/3913/3371/1282/6383/3915/1281/3673/3914/780/5155/7057/1278/4921 41 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 30/3952 39/10654 4.4886822128585125e-7 1.4105836184752204e-6 5.751157491111884e-7 9134/10528/10576/10574/6468/10564/54461/10693/10575/898/10517/26985/26190/10238/7157/26224/8237/6774/26272/26270/22948/84261/10694/8841/7203/908/6950/3801/55294/26234 30 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-203927 MicroRNA (miRNA) biogenesis 21/3952 24/10654 4.794309433710779e-7 1.4998413971676288e-6 6.115074621470837e-7 5431/5435/5433/5439/192669/29102/5438/54487/57510/26523/23405/5434/5436/5901/5432/27161/5440/5430/5441/192670/5437 21 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-3371571 HSF1-dependent transactivation 21/3952 24/10654 4.794309433710779e-7 1.4998413971676288e-6 6.115074621470837e-7 817/3305/1387/2475/3306/3312/818/3303/3337/3297/57521/1410/64223/816/3326/3304/10728/815/3320/2033/2288 21 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5685942 HDR through Homologous Recombination (HRR) 45/3952 67/10654 5.344368075470919e-7 1.668163428500923e-6 6.801348372805098e-7 83990/9156/1763/7486/5982/472/4683/84126/672/6117/10714/83695/7314/6118/5888/116028/5985/5984/6233/5884/5810/80010/580/11073/641/5111/6119/3364/10524/144715/1111/79728/51426/7311/5983/5883/10111/675/545/7316/79008/10635/5932/7156/5981 45 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 17/3952 18/10654 5.461984117753749e-7 1.6972474137718026e-6 6.919928071003219e-7 8792/10673/8740/7187/51330/958/9020/8742/959/4055/8600/330/115650/4050/7186/329/4049 17 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 17/3952 18/10654 5.461984117753749e-7 1.6972474137718026e-6 6.919928071003219e-7 2810/6790/1647/7027/5934/983/7157/891/5111/1874/25946/5933/2033/995/10498/581/3276 17 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5696400 Dual Incision in GG-NER 31/3952 41/10654 5.617627533838381e-7 1.741715322433373e-6 7.101230294184797e-7 5982/7507/9978/2965/2067/2967/6117/10714/7314/6118/404672/1643/5985/2068/5984/6233/8451/8450/5111/2966/6119/1642/142/2071/51426/7311/5983/10038/7316/2968/5981 31 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5621575 CD209 (DC-SIGN) signaling 19/3952 21/10654 5.642940774928896e-7 1.7456669791483822e-6 7.117341781530293e-7 9252/4893/4790/1387/2534/3385/5894/3845/3265/5062/5567/5970/5568/3384/5566/4067/5971/5058/2033 19 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-4551638 SUMOylation of chromatin organization proteins 47/3952 71/10654 5.761256195007593e-7 1.7783077455256767e-6 7.250423000968621e-7 1912/23165/6045/80012/348995/6613/57122/23511/9759/1911/23279/23225/23512/57332/1107/9972/6612/8021/55746/10762/79902/9883/84733/3066/9063/6396/129401/6015/8554/4928/5903/55706/7175/8535/4927/8086/7329/648/9631/79023/23636/53371/9688/7341/3065/6304/8480 47 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 38/3952 54/10654 6.695242436284729e-7 2.0574539256636036e-6 8.388543154916592e-7 5295/4893/5291/9965/2264/2885/8660/2252/3845/3265/2323/54106/5290/3667/8074/2260/2248/2247/8471/2246/5781/5170/6464/8483/2322/2263/3481/208/9365/6654/2549/3480/2254/10818/2261/2255/3479/5296 38 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-74751 Insulin receptor signalling cascade 38/3952 54/10654 6.695242436284729e-7 2.0574539256636036e-6 8.388543154916592e-7 5295/3643/4893/5291/9965/2264/3630/2885/8660/2252/3845/3265/2323/54106/5290/3667/5594/8074/2260/2248/2247/2246/5781/5170/6464/2322/2263/208/9365/6654/2549/5595/2254/10818/2261/2255/5296/2887 38 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-72312 rRNA processing 110/3952 205/10654 8.165063592666955e-7 2.5035923466256956e-6 1.0207515308132503e-6 6158/5393/6138/6227/6206/6234/6191/6128/6132/6129/55226/6176/10528/27043/6224/6146/6154/6202/6169/55272/6175/6218/6173/6167/23481/6192/6156/117246/6143/6139/26168/11340/3921/6208/6170/10813/6203/6147/6222/1454/51602/6134/6155/6231/6142/23521/6207/10969/6233/6188/1453/4691/23016/6122/6230/2091/8602/6194/6166/3028/10436/6136/6125/6232/6160/6193/10200/6210/6229/6205/140801/6235/6181/7311/6223/25873/26354/9045/6187/6168/6157/6137/79050/6144/9349/4736/51121/6159/25879/6217/6152/51065/6141/6164/54931/6209/11224/6165/6130/6204/1736/6228/6124/83732/6189/6135/6201/54512/6133/9188 110 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-169893 Prolonged ERK activation events 14/3952 14/10654 9.203623575980355e-7 2.7610870727941063e-6 1.1257359290388613e-6 5605/1399/5594/4914/673/2889/7529/5595/5604/57498/10818/4803/1398/5906 14 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 14/3952 14/10654 9.203623575980355e-7 2.7610870727941063e-6 1.1257359290388613e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-4839744 truncated APC mutants destabilize the destruction complex 14/3952 14/10654 9.203623575980355e-7 2.7610870727941063e-6 1.1257359290388613e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-4839748 AMER1 mutants destabilize the destruction complex 14/3952 14/10654 9.203623575980355e-7 2.7610870727941063e-6 1.1257359290388613e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5467337 APC truncation mutants have impaired AXIN binding 14/3952 14/10654 9.203623575980355e-7 2.7610870727941063e-6 1.1257359290388613e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 14/3952 14/10654 9.203623575980355e-7 2.7610870727941063e-6 1.1257359290388613e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 14/3952 14/10654 9.203623575980355e-7 2.7610870727941063e-6 1.1257359290388613e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 14/3952 14/10654 9.203623575980355e-7 2.7610870727941063e-6 1.1257359290388613e-6 9134/57060/1869/8900/144455/898/890/7157/79733/1820/1017/25946/1027/1026 14 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 14/3952 14/10654 9.203623575980355e-7 2.7610870727941063e-6 1.1257359290388613e-6 7159/51230/23368/5458/10000/7157/5457/54971/8626/208/7161/25946/207/10848 14 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-877312 Regulation of IFNG signaling 14/3952 14/10654 9.203623575980355e-7 2.7610870727941063e-6 1.1257359290388613e-6 5777/5770/9021/3459/3717/3458/5781/8554/6772/8651/5771/3716/3460/7341 14 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-418990 Adherens junctions interactions 26/3952 33/10654 1.1943941642425106e-6 3.575460116665619e-6 1.457767832038273e-6 283/71/5817/1006/1500/999/3728/1008/1012/64403/1016/1010/23705/1003/1007/1002/1000/1009/60/1015/1495/1499/1004/1005/1001/1013 26 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2428924 IGF1R signaling cascade 37/3952 53/10654 1.285806850995917e-6 3.840829496845869e-6 1.5659628428654295e-6 5295/4893/5291/9965/2264/2885/8660/2252/3845/3265/2323/54106/5290/3667/8074/2260/2248/2247/8471/2246/5781/5170/6464/2322/2263/3481/208/9365/6654/2549/3480/2254/10818/2261/2255/3479/5296 37 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-201451 Signaling by BMP 23/3952 28/10654 1.3232349102698313e-6 3.944148691769948e-6 1.608087602722316e-6 7321/91851/4089/650/11167/6497/7323/93/4092/92/94/4091/4090/4093/9765/57154/9241/4086/658/64750/659/657/27302 23 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-167044 Signalling to RAS 18/3952 20/10654 1.384340021857158e-6 4.110182277527316e-6 1.675781944837025e-6 4893/5898/1432/5603/2885/3845/3265/9261/6714/4914/5600/6300/6464/7867/6654/25759/53358/4803 18 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-432142 Platelet sensitization by LDL 16/3952 17/10654 1.3966926097861002e-6 4.110182277527316e-6 1.675781944837025e-6 5777/5526/5175/2268/1432/5518/5515/5528/5519/5781/338/5529/5516/5321/5525/5527 16 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5655862 Translesion synthesis by POLK 16/3952 17/10654 1.3966926097861002e-6 4.110182277527316e-6 1.675781944837025e-6 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/51426/7311/5983/7316/5981/5980 16 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5656121 Translesion synthesis by POLI 16/3952 17/10654 1.3966926097861002e-6 4.110182277527316e-6 1.675781944837025e-6 5982/6117/7314/6118/11201/51455/5985/5984/6233/5111/6119/7311/5983/7316/5981/5980 16 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9034015 Signaling by NTRK3 (TRKC) 16/3952 17/10654 1.3966926097861002e-6 4.110182277527316e-6 1.675781944837025e-6 5295/4893/5335/2885/3845/3265/5290/3667/6714/25920/4908/6464/5802/6654/4916/581 16 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 16/3952 17/10654 1.3966926097861002e-6 4.110182277527316e-6 1.675781944837025e-6 2308/857/2290/57060/2660/4089/1647/4088/5934/4303/901/9314/4087/2309/1027/1026 16 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-382556 ABC-family proteins mediated transport 62/3952 103/10654 1.4825468260635137e-6 4.353610024106175e-6 1.77503102797857e-6 5689/5682/8714/143471/5705/5709/5695/5711/5683/5699/5702/4363/5696/5691/7314/5718/5700/122706/5707/79139/91445/23198/9861/8894/5698/5692/5713/5710/5719/10613/6233/10058/1968/5243/5706/335/5714/22/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 62 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-72766 Translation 147/3952 291/10654 1.5256125194915542e-6 4.470624028636643e-6 1.8227393637274178e-6 6158/6138/5464/6227/6206/6234/27335/6191/6128/6132/6129/1915/9255/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/6192/6156/6143/28973/51116/6139/64975/3921/8665/6208/6170/6203/51253/29093/6147/8666/6222/64432/8667/6727/7818/6184/6183/2935/6134/6747/55699/6155/10240/6231/6142/7458/8663/23521/23107/8894/1981/6185/6207/64978/6726/6233/28957/51386/6188/64965/7284/6122/1968/6230/6194/6166/1938/1650/1983/6136/6125/1937/6232/6160/6748/29927/1933/6193/6210/6229/6205/54148/140801/6235/6181/1975/7311/6223/25873/23708/9045/6187/6168/6157/6137/54460/55037/6144/6182/9349/4736/327/51121/6159/56945/9521/6217/1936/6152/79590/51065/6141/10480/6164/63931/8661/9669/6209/1964/11224/6165/6130/6204/64969/6228/7965/78988/6124/3646/6189/6135/6201/51649/6133/51021 147 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8856688 Golgi-to-ER retrograde transport 76/3952 133/10654 1.8224686802590032e-6 5.329282098694222e-6 2.172826925161981e-6 11014/64837/51807/347688/5861/7278/1780/5048/8655/832/10112/636/7846/2590/51226/81027/11004/81930/54732/79861/29127/23299/8398/1315/3796/11316/56992/8729/23423/10376/1314/10540/3835/3833/378/9493/26958/140735/84364/22820/84617/11258/1783/10382/3832/7277/1639/81876/9183/1062/146909/347733/51143/10383/24137/84790/84643/5049/7280/829/22931/1778/55582/5321/51014/5050/112714/1781/10121/10972/4905/9276/3799/375/22818/372 76 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-983231 Factors involved in megakaryocyte development and platelet production 92/3952 168/10654 2.030222602076194e-6 5.922420940354196e-6 2.414658380440724e-6 9927/3443/64837/11311/51807/347688/7278/832/3043/10112/3717/7846/81027/11004/2626/7465/81930/5879/3445/25/79861/5868/23348/23186/5567/29127/3444/5573/91768/3796/23414/3451/3448/56992/10376/3066/7157/3439/55669/3835/3833/221037/3452/9493/81704/3660/3446/9732/84617/85440/10019/10382/5568/3832/7277/3046/3659/5566/1062/146909/347733/3440/4602/998/7975/5577/10383/24137/60/25942/84790/84643/3456/1020/7280/829/55582/1017/3441/2624/5575/2625/25970/3449/81928/112714/3705/5576/3065/23028/3799/10938 92 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1500931 Cell-Cell communication 74/3952 129/10654 2.033833541071959e-6 5.922420940354196e-6 2.414658380440724e-6 5295/5777/6711/1365/283/71/5291/3688/3852/2534/87/8976/2885/6709/8826/8440/5829/5817/3655/3918/9076/5290/1006/50848/1500/5339/6714/999/3909/3728/1008/1012/64403/5781/3691/8573/1016/1308/5747/2316/1010/1366/23705/1003/1007/140885/81/10979/1002/1000/1364/23607/1009/2185/60/1015/1495/1499/5584/4690/9459/50855/1004/3611/667/1005/7408/3914/88/56288/1001/5296/55742/1013 74 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2428928 IRS-related events triggered by IGF1R 36/3952 52/10654 2.450495699194834e-6 7.105925941924059e-6 2.8971908277482052e-6 5295/4893/5291/9965/2264/2885/8660/2252/3845/3265/2323/54106/5290/3667/8074/2260/2248/2247/8471/2246/5781/5170/2322/2263/3481/208/9365/6654/2549/3480/2254/10818/2261/2255/3479/5296 36 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-75153 Apoptotic execution phase 36/3952 52/10654 2.450495699194834e-6 7.105925941924059e-6 2.8971908277482052e-6 2339/10059/660/836/324/9414/4001/3836/6709/840/5062/2934/63967/841/100506658/7082/5339/28988/10134/999/5580/839/5747/118/1829/8428/1832/4000/3837/51765/1499/3146/329/4137/7431/6304 36 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-209543 p75NTR recruits signalling complexes 13/3952 13/10654 2.486310192231711e-6 7.15007216772225e-6 2.9151898952177416e-6 8878/3654/3551/7314/8767/6233/7189/7311/4804/5584/4615/7316/4803 13 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-209560 NF-kB is activated and signals survival 13/3952 13/10654 2.486310192231711e-6 7.15007216772225e-6 2.9151898952177416e-6 4790/8878/4792/3654/3551/7314/5970/6233/7189/7311/4804/7316/4803 13 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5357786 TNFR1-induced proapoptotic signaling 13/3952 13/10654 2.486310192231711e-6 7.15007216772225e-6 2.9151898952177416e-6 7124/7375/1540/8737/841/7128/8772/8717/27005/7186/56957/7132/9099 13 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13/3952 13/10654 2.486310192231711e-6 7.15007216772225e-6 2.9151898952177416e-6 7531/10971/7533/2810/11200/7465/7534/983/7532/891/1111/7529/995 13 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5654743 Signaling by FGFR4 30/3952 41/10654 2.781642967006845e-6 7.978730395472257e-6 3.2530460784086046e-6 5295/4893/5335/9965/2264/2885/5518/3845/3265/7314/5515/5290/5594/8074/6714/2247/6233/2246/5781/6464/673/6654/7311/2549/5595/5516/2254/7316/10818/867 30 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 38/3952 56/10654 2.7859497781166625e-6 7.978730395472257e-6 3.2530460784086046e-6 5469/1387/2101/84808/10499/23054/1386/3054/7019/814/23408/5465/64784/2747/4208/55902/6742/801/133522/805/5442/3418/23410/4209/2553/6648/23373/8841/200186/9611/23409/54205/6256/10498/1385/808/8648/10891 38 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1236394 Signaling by ERBB4 39/3952 58/10654 2.9258817207945724e-6 8.362242202023993e-6 3.4094094992148154e-6 5295/4893/2670/51741/23385/6776/4734/10413/83737/6868/2885/3845/3265/7314/6387/1839/5290/6678/2065/2069/23118/348/11059/6714/2099/2567/3925/6233/5663/6464/5241/6654/7311/1956/7316/1950/9611/2066/6285 39 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1538133 G0 and Early G1 22/3952 27/10654 2.9558996506738098e-6 8.430687094016266e-6 3.437315491327158e-6 9134/1869/4609/5928/990/8900/7027/7153/898/5934/993/890/983/1859/5111/1874/1017/4605/4149/1875/5933/3065 22 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-110312 Translesion synthesis by REV1 15/3952 16/10654 3.559392015840891e-6 1.0089786755108157e-5 4.113754896933189e-6 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/7311/5983/7316/5981/5980 15 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1433559 Regulation of KIT signaling 15/3952 16/10654 3.559392015840891e-6 1.0089786755108157e-5 4.113754896933189e-6 5777/5578/2534/2885/3815/9306/6714/7525/3932/10019/8651/4067/6654/867/4254 15 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 15/3952 16/10654 3.559392015840891e-6 1.0089786755108157e-5 4.113754896933189e-6 8454/4790/3551/7314/8945/8517/6233/79155/7311/6416/1147/5604/6500/7316/23291 15 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-167287 HIV elongation arrest and recovery 27/3952 36/10654 4.032691053611994e-6 1.1384975352575325e-5 4.641822393759635e-6 5431/5435/5433/5439/11198/904/51497/5438/1025/6829/25920/2963/5434/5436/2962/8812/905/5432/6917/5440/5430/6749/5441/9150/5437/6827/8178 27 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-167290 Pausing and recovery of HIV elongation 27/3952 36/10654 4.032691053611994e-6 1.1384975352575325e-5 4.641822393759635e-6 5431/5435/5433/5439/11198/904/51497/5438/1025/6829/25920/2963/5434/5436/2962/8812/905/5432/6917/5440/5430/6749/5441/9150/5437/6827/8178 27 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-201681 TCF dependent signaling in response to WNT 120/3952 233/10654 4.133786980182695e-6 1.1646714230169904e-5 4.748537195128195e-6 27123/9070/5689/857/5682/1459/5526/1452/5929/1460/143471/5705/6657/8452/50964/5709/9978/5695/1457/4609/5711/1387/5683/324/5699/8312/5702/1855/6932/5518/6659/80351/5696/5691/7314/5515/5718/51176/8945/6662/5700/122706/5707/1856/1454/8322/23198/9101/7471/7534/5528/83439/59349/9861/81847/5519/2932/5698/5692/5713/5710/8313/5719/6233/7474/1857/7514/331/8607/4221/123169/6597/864/5706/8658/5714/6934/10524/5688/5687/5708/5529/7088/208/57680/5704/7311/5694/5516/5684/8295/5720/7015/1487/1499/5525/139285/207/5690/5717/9491/10197/64750/7316/10213/64321/5715/5701/1455/5685/5686/2033/54894/3065/5527/5716/23072/5693/5721/6259 120 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-452723 Transcriptional regulation of pluripotent stem cells 20/3952 24/10654 4.434715882142211e-6 1.241899266188615e-5 5.063406503804138e-6 64344/79727/6657/55211/4089/84891/2516/5460/5087/2247/63978/6774/9314/79923/4087/2034/7547/6997/27086/57167 20 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8940973 RUNX2 regulates osteoblast differentiation 20/3952 24/10654 4.434715882142211e-6 1.241899266188615e-5 5.063406503804138e-6 5925/10413/25/5594/3280/10013/2737/865/6714/7525/1277/23493/367/860/5595/8841/23462/4094/25925/25937 20 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 20/3952 24/10654 4.434715882142211e-6 1.241899266188615e-5 5.063406503804138e-6 374/7039/1839/5594/2069/10000/595/7514/2353/5747/208/1956/5595/596/2309/207/6722/1027/1950/1385 20 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5696394 DNA Damage Recognition in GG-NER 28/3952 38/10654 4.796877740017114e-6 1.3406163341818454e-5 5.465890552005099e-6 9978/10980/10987/7314/86/1643/10920/6233/8607/5886/8451/8450/1642/142/1069/2873/7311/60/8533/10038/51138/7528/9318/7316/64708/5887/50813/7508 28 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5654741 Signaling by FGFR3 29/3952 40/10654 5.5520249872411575e-6 1.54854672836907e-5 6.3136534414198744e-6 5295/4893/5335/2885/5518/3845/3265/7314/5515/5290/5594/8074/6714/2247/6233/2246/5781/6464/673/6654/7311/2549/5595/5516/2254/7316/10818/2261/867 29 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 41/3952 63/10654 5.792953920967906e-6 1.612507614473832e-5 6.574431409093417e-6 4790/5435/4792/3428/1387/22954/1660/3551/7314/11035/8737/29110/8517/6778/51428/5970/3661/6233/11128/4791/3665/5434/7098/9208/5591/7311/2547/1147/170506/5440/6737/1499/7520/5441/51082/4615/7316/4793/5437/2033/148022 41 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 68/3952 119/10654 6.272036783339984e-6 1.7423718184118478e-5 7.10390692513034e-6 9441/34/892/1543/5469/9612/27242/1387/2101/84246/4801/2274/55588/10499/23054/9575/9282/10062/7296/51129/5465/6667/23309/336/3156/183/116519/9412/405/133522/54797/9440/6721/9442/406/335/4800/1024/10001/9971/9443/9477/1579/25942/51586/6095/6822/8841/5468/29079/4802/4862/90390/6720/6837/9611/2874/2033/9967/6256/51003/7376/10498/112950/196/8202/8648/10891 68 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5619115 Disorders of transmembrane transporters 94/3952 176/10654 6.543827547928261e-6 1.8129668033749732e-5 7.391733092461337e-6 23165/5689/5682/285195/348995/143471/57122/5705/23511/5709/5695/554/23279/5711/6505/23225/5683/5699/5702/6531/9972/8021/55746/5696/5691/6513/7314/5718/5700/122706/5707/79139/91445/23198/10762/9861/79902/9883/5698/5692/5713/5710/5719/10613/6233/6396/129401/10058/4928/5903/55706/7175/5706/335/5714/4927/5688/5687/5708/8086/6514/5704/7311/11160/5694/5684/5720/9631/5690/5717/9491/1080/79023/23636/10197/7316/10213/53371/3098/9688/7415/5715/5701/5685/682/5686/6520/5716/213/5693/551/5721/8480/1356 94 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-180024 DARPP-32 events 21/3952 26/10654 6.552263033075857e-6 1.8129668033749732e-5 7.391733092461337e-6 5530/5499/5518/5515/84152/5567/5573/5528/5519/801/805/5568/5566/5577/1020/5141/5516/5575/5576/5534/808 21 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-170968 Frs2-mediated activation 12/3952 12/10654 6.715561691809603e-6 1.8254237162276984e-5 7.442521763711128e-6 5605/1399/5594/4914/673/2889/7529/5595/5604/10818/4803/5906 12 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-190873 Gap junction degradation 12/3952 12/10654 6.715561691809603e-6 1.8254237162276984e-5 7.442521763711128e-6 71/1212/1785/2697/1759/4646/1601/1213/1211/1173/8218/60 12 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2197563 NOTCH2 intracellular domain regulates transcription 12/3952 12/10654 6.715561691809603e-6 1.8254237162276984e-5 7.442521763711128e-6 4853/9794/388585/55534/3280/84441/3002/10046/2208/2033/1385/3516 12 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 12/3952 12/10654 6.715561691809603e-6 1.8254237162276984e-5 7.442521763711128e-6 834/55367/472/8738/7157/839/317/843/8626/7161/835/58484 12 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 12/3952 12/10654 6.715561691809603e-6 1.8254237162276984e-5 7.442521763711128e-6 7159/23368/8797/7157/8626/7161/8795/8793/3486/355/8794/124446 12 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8866427 VLDLR internalisation and degradation 12/3952 12/10654 6.715561691809603e-6 1.8254237162276984e-5 7.442521763711128e-6 163/10062/161/7436/1213/1211/1175/29116/1173/160/255738/7376 12 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8984722 Interleukin-35 Signalling 12/3952 12/10654 6.715561691809603e-6 1.8254237162276984e-5 7.442521763711128e-6 3717/3572/10148/3592/7297/6775/3595/821/6774/6772/3716/9466 12 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 12/3952 12/10654 6.715561691809603e-6 1.8254237162276984e-5 7.442521763711128e-6 7187/7314/29110/3661/6233/10010/3665/7098/7311/9641/7316/148022 12 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9020558 Interleukin-2 signaling 12/3952 12/10654 6.715561691809603e-6 1.8254237162276984e-5 7.442521763711128e-6 6776/3558/3718/3932/6777/6464/6850/3716/2185/3561/3560/3559 12 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-389356 CD28 co-stimulation 25/3952 33/10654 6.835358313841617e-6 1.854357948813673e-5 7.560490898122514e-6 5295/941/2534/2885/2475/5062/5879/5290/9020/6714/10000/7525/3932/940/253260/5170/64223/8503/4067/998/208/5058/207/942/5296 25 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 16/3952 18/10654 8.200646193871894e-6 2.211785934619041e-5 9.017777521314419e-6 5295/11052/613/6776/11064/2885/7750/8805/26127/5290/399687/6777/1523/9208/6774/6772 16 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-190840 Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane 16/3952 18/10654 8.200646193871894e-6 2.211785934619041e-5 9.017777521314419e-6 51807/347688/2697/7278/7846/81027/79861/10376/84617/10382/7277/347733/10383/84790/7280/112714 16 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 16/3952 18/10654 8.200646193871894e-6 2.211785934619041e-5 9.017777521314419e-6 4893/5578/2885/6196/6197/3845/3265/1839/5594/5598/6195/6654/1956/5595/4314/1385 16 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5654736 Signaling by FGFR1 34/3952 50/10654 8.686210358787633e-6 2.3382066256503916e-5 9.533213327269986e-6 5295/4893/5335/2885/5518/3845/3265/7314/5515/5290/5594/8074/2260/6714/2248/2247/6233/2246/200734/5781/6464/673/9365/6654/7311/2549/5595/5516/2254/7316/10818/867/2255/161742 34 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69205 G1/S-Specific Transcription 22/3952 28/10654 8.942337032155023e-6 2.40249635157898e-5 9.795332023413219e-6 5422/1869/4998/5928/990/8900/6241/7027/898/5934/983/7298/1719/26271/8318/5111/1874/81620/1875/5933/3065/7083 22 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-111447 Activation of BAD and translocation to mitochondria 14/3952 15/10654 9.036505147890214e-6 2.409156554783015e-5 9.82248665433869e-6 7531/10971/7533/2810/637/7534/10000/572/7532/208/7529/596/207/5534 14 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5099900 WNT5A-dependent internalization of FZD4 14/3952 15/10654 9.036505147890214e-6 2.409156554783015e-5 9.82248665433869e-6 5578/1212/5582/163/161/1856/8322/7474/1213/1211/1175/1173/409/160 14 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-937039 IRAK1 recruits IKK complex 14/3952 15/10654 9.036505147890214e-6 2.409156554783015e-5 9.82248665433869e-6 3654/7334/3551/7314/8517/6233/57162/7189/7311/1147/246330/7316/7335/57161 14 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 14/3952 15/10654 9.036505147890214e-6 2.409156554783015e-5 9.82248665433869e-6 3654/7334/3551/7314/8517/6233/57162/7189/7311/1147/246330/7316/7335/57161 14 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-72165 mRNA Splicing - Minor Pathway 35/3952 52/10654 9.126209737095596e-6 2.4284109817673913e-5 9.900989793420914e-6 6633/6431/4904/51639/23450/5431/5435/5433/5439/9410/6432/5438/9343/6636/2963/6635/5434/6632/24148/5436/6637/2962/6426/5432/22916/23451/5440/5430/5441/10594/4686/5437/6634/10992/6628 35 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1474228 Degradation of the extracellular matrix 77/3952 140/10654 1.095773613661462e-5 2.910190342974705e-5 1.1865275317497569e-5 960/11131/23385/92291/1280/1289/6696/176/825/6650/1303/836/2200/6868/4325/84290/63827/50859/826/3918/7373/4316/5340/4320/26254/10753/823/1284/2006/4312/4313/102/388743/999/827/2335/3909/1288/726/4326/1292/7076/5663/1291/1508/7077/1308/8754/4318/11132/1277/3912/147968/23473/4322/8751/222663/4321/5650/4319/1282/1991/5045/1634/831/649/4314/3915/824/1281/682/440854/3914/2/80781/1278/4323 77 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 23/3952 30/10654 1.1498348491807332e-5 3.047940086855035e-5 1.2426901343094308e-5 56852/5982/9978/57599/6117/10714/7314/51514/6118/5985/5984/6233/8451/8450/5111/6119/1642/7311/5983/7320/7316/7398/5981 23 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8875878 MET promotes cell motility 29/3952 41/10654 1.2247114869474111e-5 3.2402366768951506e-5 1.32109229068212e-5 5908/3082/1280/1289/3688/3910/2885/1399/5879/3918/284217/6714/2335/3909/85440/5747/1277/3912/4233/2889/3913/2549/3915/1281/3673/3914/1398/5906/1278 29 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-72163 mRNA Splicing - Major Pathway 96/3952 183/10654 1.4044662957242004e-5 3.7087522523971756e-5 1.5121130020004401e-5 6633/8683/6431/4904/51639/51585/23450/5431/9092/5435/6625/5433/3190/22938/988/3181/5439/1660/9410/6638/3312/10291/6432/6627/11051/8106/55749/5438/11338/1655/9343/3185/6626/24144/10236/10250/4670/55660/2521/3191/6636/23524/10914/3188/56259/5725/1994/7536/2963/6635/5434/220988/6632/24148/5436/10523/6428/27258/6637/5093/2962/23658/5094/6426/5432/22916/11100/10921/22827/23451/5440/5430/3184/25804/29894/51503/3178/5441/3183/10594/4686/10713/7307/5437/10189/10949/57794/27316/3187/6634/51593/9775/3192/10992/55339/6628 96 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2871796 FCERI mediated MAPK activation 24/3952 32/10654 1.4118078723915474e-5 3.7210647718251604e-5 1.5171329977961704e-5 3725/4893/5335/2885/3845/3265/5062/5879/5601/5336/5594/4214/2353/6464/10451/6850/4067/5602/6654/5058/6416/5595/5609/5599 24 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9612973 Autophagy 67/3952 119/10654 1.43955550923203e-5 3.76773995720539e-5 1.5361631593925964e-5 9927/5563/2670/65018/1459/1915/9140/8878/1460/53632/84938/5116/55048/9474/8655/1457/3043/3920/55054/2475/84557/10670/3312/11315/7314/64422/25978/9821/51422/7249/10533/10013/6714/55669/6233/9804/51001/57521/140735/7405/389541/7416/64223/5571/128866/6009/3326/7311/5562/93343/11345/55626/7251/5564/5565/7248/10452/1080/7316/8678/56993/10226/3320/81631/10542/23710/7431 67 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 20/3952 25/10654 1.4403671110698793e-5 3.76773995720539e-5 1.5361631593925964e-5 9252/1848/1432/6196/5518/6197/51231/5515/5594/5528/9261/5519/5598/4208/6195/5600/5595/5516/466/1385 20 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 20/3952 25/10654 1.4403671110698793e-5 3.76773995720539e-5 1.5361631593925964e-5 22938/1387/9794/9787/388585/2648/55534/3280/84441/4854/10320/8850/5087/10046/6772/23493/4851/23462/2033/3516 20 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 20/3952 25/10654 1.4403671110698793e-5 3.76773995720539e-5 1.5361631593925964e-5 3107/10484/811/567/3106/3309/9632/3133/22872/10134/51128/6396/3135/10802/821/2923/9871/3105/3134/10427 20 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1989781 PPARA activates gene expression 66/3952 117/10654 1.528650926113332e-5 3.9911581510740946e-5 1.627254052728478e-5 9441/34/892/1543/5469/9612/27242/1387/2101/84246/4801/2274/55588/10499/23054/9575/9282/10062/7296/51129/5465/6667/336/3156/183/116519/9412/405/133522/54797/9440/6721/9442/406/335/4800/1024/10001/9971/9443/9477/1579/51586/6095/6822/8841/5468/29079/4802/4862/90390/6720/6837/9611/2874/2033/9967/6256/51003/7376/10498/112950/196/8202/8648/10891 66 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 25/3952 34/10654 1.67111322045133e-5 4.346772028477336e-5 1.7722430762917714e-5 5431/5435/5433/5439/11198/904/51497/5438/1025/6829/25920/2963/5434/5436/2962/5432/6917/5440/5430/6749/5441/9150/5437/6827/8178 25 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 25/3952 34/10654 1.67111322045133e-5 4.346772028477336e-5 1.7722430762917714e-5 5431/5435/5433/5439/11198/904/51497/5438/1025/6829/25920/2963/5434/5436/2962/5432/6917/5440/5430/6749/5441/9150/5437/6827/8178 25 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-70171 Glycolysis 44/3952 71/10654 1.7290699357301002e-5 4.4891180200544097e-005 1.830279636837765e-5 23165/7167/348995/57122/3099/23511/23279/23225/9972/5518/8021/55746/5515/2597/5567/10762/5528/79902/5519/9883/226/6396/129401/230/4928/5903/55706/7175/5568/4927/5566/2023/8086/5516/9631/5315/79023/23636/5214/53371/5230/3098/9688/8480 44 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9006931 Signaling by Nuclear Receptors 146/3952 299/10654 1.7441486560943487e-5 4.519818065886288e-5 1.8427964983871952e-5 5295/374/3725/4893/857/5160/2770/10901/7039/27327/10274/5431/5435/5433/5469/9612/4609/55818/1387/8312/2782/5439/192669/10499/1386/5914/4343/3845/904/1071/7392/3265/2773/10062/6387/1839/5290/4316/5594/2069/10681/5481/5438/348/4313/865/1655/6667/6714/2099/2494/8850/5467/10000/5162/595/2783/2771/7514/1025/2353/26523/801/29116/2957/805/5105/5170/2963/3838/5434/5590/6464/112724/5241/5747/5436/3315/4318/200845/5885/2962/8503/10524/8243/4602/208/3326/6908/1956/3169/5432/3480/10728/5595/7528/3727/27161/2354/596/5440/8841/4435/2309/9687/59345/5430/207/5451/2625/57690/6722/1027/5441/10735/6720/192670/2100/1950/9611/2874/2194/4314/7391/2958/5437/3320/2033/4846/9126/3065/2066/861/23028/6256/23112/7376/10498/1385/1738/5296/808/3276/8202/8648/2288 146 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1059683 Interleukin-6 signaling 11/3952 11/10654 1.8135935824899698e-5 4.596864025690818e-5 1.8742092727230196e-5 9021/3717/3569/3572/3570/7297/5781/6774/6772/3716/867 11 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-196025 Formation of annular gap junctions 11/3952 11/10654 1.8135935824899698e-5 4.596864025690818e-5 1.8742092727230196e-5 71/1212/1785/2697/1759/1601/1213/1211/1173/8218/60 11 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2514853 Condensation of Prometaphase Chromosomes 11/3952 11/10654 1.8135935824899698e-5 4.596864025690818e-5 1.8742092727230196e-5 1459/1460/1457/64151/10051/983/23397/9133/891/10592/9918 11 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2586552 Signaling by Leptin 11/3952 11/10654 1.8135935824899698e-5 4.596864025690818e-5 1.8742092727230196e-5 3953/9021/6776/3717/8660/3667/3952/6777/5781/6774/25970 11 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-3371378 Regulation by c-FLIP 11/3952 11/10654 1.8135935824899698e-5 4.596864025690818e-5 1.8742092727230196e-5 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355 11 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-4755510 SUMOylation of immune response proteins 11/3952 11/10654 1.8135935824899698e-5 4.596864025690818e-5 1.8742092727230196e-5 4792/6612/51588/8517/5970/4791/10210/7329/9641/7341/10401 11 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5218900 CASP8 activity is inhibited 11/3952 11/10654 1.8135935824899698e-5 4.596864025690818e-5 1.8742092727230196e-5 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355 11 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5655291 Signaling by FGFR4 in disease 11/3952 11/10654 1.8135935824899698e-5 4.596864025690818e-5 1.8742092727230196e-5 5295/4893/5335/2264/2885/3845/3265/5290/6654/2549/10818 11 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69416 Dimerization of procaspase-8 11/3952 11/10654 1.8135935824899698e-5 4.596864025690818e-5 1.8742092727230196e-5 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355 11 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8875555 MET activates RAP1 and RAC1 11/3952 11/10654 1.8135935824899698e-5 4.596864025690818e-5 1.8742092727230196e-5 5908/3082/2885/1399/5879/85440/4233/2889/2549/1398/5906 11 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 11/3952 11/10654 1.8135935824899698e-5 4.596864025690818e-5 1.8742092727230196e-5 7314/257397/23118/10454/6233/7098/7189/7311/6885/7316/148022 11 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9614399 Regulation of localization of FOXO transcription factors 11/3952 11/10654 1.8135935824899698e-5 4.596864025690818e-5 1.8742092727230196e-5 2308/10971/2810/7534/10000/7532/4303/208/7529/2309/207 11 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 39/3952 61/10654 1.8200180258103734e-5 4.604745059837174e-5 1.8774224865995226e-5 71/147179/10094/8976/2885/5879/26999/25/1072/10093/10006/4771/5594/4644/4641/10109/10787/5747/2209/10451/6850/10092/10163/998/3326/10097/60/5058/5595/4690/4627/10458/10552/917/3320/1398/10096/9844/10095 39 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-354192 Integrin alphaIIb beta3 signaling 21/3952 27/10654 1.913953487148305e-5 4.824830115515419e-5 1.9671544103272297e-5 5770/5908/2244/3690/2885/9564/7094/6714/2335/1445/2266/2243/5170/6464/5747/6850/6654/7450/207/1398/5906 21 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9006921 Integrin signaling 21/3952 27/10654 1.913953487148305e-5 4.824830115515419e-5 1.9671544103272297e-5 5770/5908/2244/3690/2885/9564/7094/6714/2335/1445/2266/2243/5170/6464/5747/6850/6654/7450/207/1398/5906 21 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-180292 GAB1 signalosome 15/3952 17/10654 1.9779637561251902e-5 4.968158512220414e-5 2.0255915119355712e-5 5295/374/7039/55824/2885/5829/1839/5290/2069/6714/1445/5781/1956/2549/1950 15 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-196299 Beta-catenin phosphorylation cascade 15/3952 17/10654 1.9779637561251902e-5 4.968158512220414e-5 2.0255915119355712e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-177504 Retrograde neurotrophin signalling 13/3952 14/10654 2.2843632042469578e-5 5.6761726130572894e-5 2.3142593049333654e-5 1785/6456/163/1759/161/4914/1213/1211/1175/1173/160/26052/4803 13 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-198323 AKT phosphorylates targets in the cytosol 13/3952 14/10654 2.2843632042469578e-5 5.6761726130572894e-5 2.3142593049333654e-5 7249/2932/10000/2931/23608/572/208/1147/842/207/1027/1026/4193 13 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-3371568 Attenuation phase 13/3952 14/10654 2.2843632042469578e-5 5.6761726130572894e-5 2.3142593049333654e-5 3305/1387/3306/3312/3303/3337/3297/3326/3304/10728/3320/2033/2288 13 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 13/3952 14/10654 2.2843632042469578e-5 5.6761726130572894e-5 2.3142593049333654e-5 79370/7159/23368/332/64065/7157/604/5875/8626/7161/10397/9540/5876 13 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8941856 RUNX3 regulates NOTCH signaling 13/3952 14/10654 2.2843632042469578e-5 5.6761726130572894e-5 2.3142593049333654e-5 22938/1387/9794/2648/55534/3280/84441/8850/864/10046/4851/2033/3516 13 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9027284 Erythropoietin activates RAS 13/3952 14/10654 2.2843632042469578e-5 5.6761726130572894e-5 2.3142593049333654e-5 4893/3717/2885/2056/8660/3845/3265/1399/2057/6464/2889/4067/6654 13 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5218920 VEGFR2 mediated vascular permeability 22/3952 29/10654 2.4031809912410444e-5 5.9501219194898585e-5 2.425952478258152e-5 857/2475/5062/5879/1500/10000/3728/801/253260/805/5170/10451/64223/1003/208/5058/1495/1499/207/3320/4846/808 22 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8863795 Downregulation of ERBB2 signaling 22/3952 29/10654 2.4031809912410444e-5 5.9501219194898585e-5 2.425952478258152e-5 2064/4145/7314/1839/2065/2069/9101/10000/6233/5782/10193/208/7311/1956/11140/8065/10273/207/7316/1950/3320/2066 22 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69473 G2/M DNA damage checkpoint 55/3952 95/10654 2.8353860443102274e-5 7.007742376417982e-5 2.857159939761945e-5 83990/9156/1763/7531/7486/10971/5982/7533/2810/11200/472/4683/84126/8924/672/6117/7334/7465/83695/6118/51588/51720/7534/116028/983/9656/5985/7157/5984/7158/5884/5810/80010/7532/580/11073/891/641/6119/3364/10524/144715/1111/5983/7529/5883/10111/545/7336/7341/995/5932/9025/79184/7156 55 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-199992 trans-Golgi Network Vesicle Budding 44/3952 72/10654 2.8580507277609442e-5 7.051212186252134e-5 2.874883222464968e-5 27131/8773/8906/1176/5286/1212/1174/1785/11154/7037/3482/408/6456/3312/1362/25977/10618/6643/6810/8301/9146/8729/4074/2495/152503/6844/1213/2580/1211/8907/351/9685/9026/9829/51429/64746/8673/6272/2804/7163/5878/6845/375/4952 44 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1839124 FGFR1 mutant receptor activation 23/3952 31/10654 2.8884633100818894e-5 7.113609109403802e-5 2.9003233684659514e-5 5295/11052/9530/613/6776/11064/2885/7750/8805/26127/5290/8074/2260/399687/2247/2246/6777/1523/9208/6774/6772/11160/2254 23 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-112399 IRS-mediated signalling 32/3952 48/10654 2.973184683827699e-5 7.309298275817121e-5 2.9801087282707078e-5 5295/4893/5291/9965/2264/2885/8660/2252/3845/3265/2323/54106/5290/3667/8074/2260/2248/2247/2246/5781/5170/2322/2263/208/9365/6654/2549/2254/10818/2261/2255/5296 32 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5260271 Diseases of Immune System 19/3952 24/10654 3.137852317417278e-5 7.659889049020383e-5 3.123049758154649e-5 4790/10333/4792/7187/3551/8517/5970/7096/4791/81793/7098/81622/1147/7099/4615/7100/114609/7097/148022 19 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5602358 Diseases associated with the TLR signaling cascade 19/3952 24/10654 3.137852317417278e-5 7.659889049020383e-5 3.123049758154649e-5 4790/10333/4792/7187/3551/8517/5970/7096/4791/81793/7098/81622/1147/7099/4615/7100/114609/7097/148022 19 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5627123 RHO GTPases activate PAKs 19/3952 24/10654 3.137852317417278e-5 7.659889049020383e-5 3.123049758154649e-5 2017/79784/5062/5879/4638/4659/4771/801/5500/805/2316/10627/998/5058/4629/4627/10398/4637/808 19 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-933542 TRAF6 mediated NF-kB activation 19/3952 24/10654 3.137852317417278e-5 7.659889049020383e-5 3.123049758154649e-5 4790/4792/64135/3551/4214/8517/5970/23586/4791/351/7706/7189/1147/7186/57506/4793/3146/6288/6285 19 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1839126 FGFR2 mutant receptor activation 24/3952 33/10654 3.35386664841123e-5 8.172843464286312e-5 3.332188839972746e-5 5431/5435/5433/5439/2252/8074/5438/2248/2247/2246/2963/5434/5436/2263/2962/5432/22916/5440/5430/5441/2254/4686/5437/2255 24 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-110320 Translesion Synthesis by POLH 16/3952 19/10654 3.3916980725674125e-5 8.2361339559373e-5 3.357993307032146e-5 5982/25898/6117/7314/6118/5985/5984/6233/5111/6119/83932/7311/5983/7316/7415/5981 16 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-190872 Transport of connexons to the plasma membrane 16/3952 19/10654 3.3916980725674125e-5 8.2361339559373e-5 3.357993307032146e-5 51807/347688/2697/7278/7846/81027/79861/10376/84617/10382/7277/347733/10383/84790/7280/112714 16 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-216083 Integrin cell surface interactions 50/3952 85/10654 3.6205974286707995e-5 8.776631463217697e-5 3.5783621137593284e-5 8174/960/3696/5175/3383/1280/1289/7448/6696/3688/3693/2244/3690/3694/2200/3385/3655/7412/1284/50848/3683/3672/999/2335/1288/2266/3685/1292/2243/3791/1291/3684/3384/1277/3695/4060/7450/3676/3371/1282/1281/3673/682/8516/3687/80781/7057/1278/3689/3682 50 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6798695 Neutrophil degranulation 220/3952 480/10654 3.71984611252161e-5 9.001509146851074e-5 3.6700480626015526e-5 5869/8773/7130/9798/1727/5689/5777/8514/5806/4893/9218/4790/960/5657/1915/3107/203068/9761/5175/383/2268/5908/1460/1265/29108/23385/5788/5709/10576/5695/8655/567/7133/3106/3417/3043/388698/1667/1432/3920/5683/3482/80142/5702/566/9961/51552/10075/56729/10487/684/6709/8826/9522/4282/2219/3608/3312/1654/2519/5879/51316/5718/1992/3303/2934/57554/56954/161/56888/3579/5707/3848/823/5594/4831/6727/7414/10533/847/3683/3934/1315/102/4069/965/9861/28988/226/55832/968/5713/1/2495/3614/3728/5478/5719/5328/728/5580/3685/302/1535/2040/230/317/5663/7879/8907/1508/7077/23352/23412/7276/5284/4332/1938/1650/3684/3163/79169/2760/4318/3958/79980/6993/6616/5329/966/5611/84061/1116/6279/4048/6286/10092/5795/197/140885/3310/1832/5708/3615/820/51143/80301/4860/6386/10788/6402/5473/3326/10857/10097/3916/240/10383/387/79930/5049/80184/1476/3304/2547/8673/10493/6282/114790/22931/1778/10694/3837/10890/8621/5005/29099/327/11333/5315/23197/1991/7520/5717/2919/5004/2357/10213/121260/5768/1471/9588/7415/3146/4353/5701/9342/5265/3320/5686/388697/23593/391/23071/5878/2683/1675/719/5906/89777/3687/124583/7097/1536/10970/3689/5724/51382/2950/718 220 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 27/3952 39/10654 4.5268353441778924e-5 1.0935259640109727e-4 4.458466663922575e-5 5982/25898/6117/10714/7314/6118/9636/11201/51455/5985/5984/6233/124739/7706/5111/6119/83932/9246/51426/7311/7318/5983/7316/9100/7415/5981/5980 27 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1295596 Spry regulation of FGF signaling 14/3952 16/10654 4.7376297072235384e-5 1.1424596637731762e-4 4.657976576181038e-5 2885/5518/7314/5515/5594/6714/6233/5781/673/7311/5595/5516/7316/867 14 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-110056 MAPK3 (ERK1) activation 10/3952 10/10654 4.8969787143640895e-5 1.1627185357695249e-4 4.7405749857451744e-5 3717/3569/3572/983/3570/7297/5781/3716/5595/5604 10 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 10/3952 10/10654 4.8969787143640895e-5 1.1627185357695249e-4 4.7405749857451744e-5 5563/53632/1432/51422/5600/6300/5571/5564/5565/10891 10 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-381183 ATF6 (ATF6-alpha) activates chaperone genes 10/3952 10/10654 4.8969787143640895e-5 1.1627185357695249e-4 4.7405749857451744e-5 811/3309/4801/468/7184/7494/4800/22926/4802/1649 10 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-390450 Folding of actin by CCT/TriC 10/3952 10/10654 4.8969787143640895e-5 1.1627185357695249e-4 4.7405749857451744e-5 10576/10574/10693/10575/60/22948/10694/7203/908/6950 10 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-450341 Activation of the AP-1 family of transcription factors 10/3952 10/10654 4.8969787143640895e-5 1.1627185357695249e-4 4.7405749857451744e-5 3725/1432/1386/5601/5594/2353/5600/5602/5595/5599 10 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-74749 Signal attenuation 10/3952 10/10654 4.8969787143640895e-5 1.1627185357695249e-4 4.7405749857451744e-5 3643/3630/2885/8660/3667/5594/6464/6654/5595/2887 10 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8853334 Signaling by FGFR3 fusions in cancer 10/3952 10/10654 4.8969787143640895e-5 1.1627185357695249e-4 4.7405749857451744e-5 5295/4893/2885/3845/3265/5290/6654/2549/10818/2261 10 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9020958 Interleukin-21 signaling 10/3952 10/10654 4.8969787143640895e-5 1.1627185357695249e-4 4.7405749857451744e-5 6776/50615/3718/6777/59067/6775/6774/6772/3716/3561 10 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 10/3952 10/10654 4.8969787143640895e-5 1.1627185357695249e-4 4.7405749857451744e-5 2308/7295/1387/10628/23411/8850/4303/23410/2309/2033 10 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5218921 VEGFR2 mediated cell proliferation 17/3952 21/10654 5.0280439096132006e-5 1.1918008516130948e-4 4.859147877441894e-5 4893/5335/5578/3845/3265/5921/6714/5580/3791/3710/801/805/5170/5590/7422/3708/808 17 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9012852 Signaling by NOTCH3 32/3952 49/10654 5.530901103697635e-5 1.3087600737710418e-4 5.33600787911652e-5 4904/23385/22938/1387/9794/9787/388585/7314/2648/55534/3280/84441/4854/102/10320/8850/5087/6233/5663/142678/10460/10046/6772/23493/7311/1956/4851/23462/7316/1950/2033/3516 32 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1502540 Signaling by Activin 12/3952 13/10654 5.746657968674441e-5 1.3551965905753477e-4 5.525336408090161e-5 10272/130399/4089/4088/10589/91/93/92/3625/8928/3624/4087 12 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5210891 Uptake and function of anthrax toxins 12/3952 13/10654 5.746657968674441e-5 1.3551965905753477e-4 5.525336408090161e-5 5605/5606/84168/10015/801/5608/805/6416/5604/5045/5609/808 12 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 22/3952 30/10654 5.849882881906898e-5 1.3772012411811322e-4 5.615052614568977e-5 4893/817/1739/6196/6197/3845/3265/818/57554/5594/6195/801/805/5170/2904/27330/816/5595/815/88/1385/808 22 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5656169 Termination of translesion DNA synthesis 23/3952 32/10654 6.662138317512711e-5 1.5657715944205e-4 6.383881761193052e-5 5982/6117/10714/7314/6118/9636/11201/51455/5985/5984/6233/124739/7706/5111/6119/9246/51426/7311/7318/5983/7316/9100/5981 23 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1592230 Mitochondrial biogenesis 54/3952 95/10654 6.694413615684238e-5 1.5706994108421294e-4 6.403973195658108e-5 5563/53632/3313/5469/10989/1432/1387/25813/2101/84808/10499/23054/1386/3054/7019/814/23408/51422/5465/54927/64784/2747/4208/55902/6742/5600/6300/801/133522/805/5442/3418/23410/4209/2553/5571/4580/6648/10651/5564/23373/5565/139322/8841/200186/9611/23409/54205/6256/10498/1385/808/8648/10891 54 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-3000178 ECM proteoglycans 45/3952 76/10654 7.033035695447216e-5 1.6473670456958151e-4 6.716558452384136e-5 7042/54829/1280/1289/7448/3688/176/3693/3910/1605/3690/3694/7040/7043/63827/5054/633/6678/1284/284217/4148/2335/3909/1288/3685/1292/1291/351/1277/3912/5802/3913/4060/2331/3371/1282/1634/3915/1462/1281/3673/1758/8516/3687/1278 45 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-446728 Cell junction organization 52/3952 91/10654 7.507631547350235e-5 1.7526218855915088e-4 7.145697961033927e-5 1365/283/71/3688/3852/87/5829/5817/3655/3918/9076/1006/50848/1500/5339/999/3909/3728/1008/1012/64403/3691/1016/1308/2316/1010/1366/23705/1003/1007/10979/1002/1000/1364/1009/60/1015/1495/1499/5584/9459/50855/1004/3611/667/1005/7408/3914/56288/1001/55742/1013 52 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-70326 Glucose metabolism 52/3952 91/10654 7.507631547350235e-5 1.7526218855915088e-4 7.145697961033927e-5 23165/7167/8402/348995/57122/3099/6576/23511/23279/23225/9972/5518/2538/4191/8021/55746/5515/2597/5567/10762/5528/79902/5519/9883/226/8604/6396/129401/230/5105/4928/5903/55706/7175/5568/4927/5566/2023/4190/8086/5516/9631/5315/79023/23636/5214/53371/5230/10165/3098/9688/8480 52 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-210993 Tie2 Signaling 15/3952 18/10654 7.767459439815154e-5 1.8102350942790683e-4 7.380595511516343e-5 5295/4893/5291/2885/3845/3265/5290/5781/6464/7010/2888/6654/5296/284/9046 15 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 25/3952 36/10654 8.030467998672334e-5 1.8683953182840657e-4 7.617723324139497e-5 71/147179/10094/8976/2885/5879/26999/25/10093/10006/5594/10109/10787/5747/10092/10163/998/10097/60/5595/4690/10458/10552/10096/10095 25 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-937041 IKK complex recruitment mediated by RIP1 19/3952 25/10654 8.513222137517376e-5 1.977402265721009e-4 8.06216072871739e-5 7321/7334/3551/7314/11035/8737/8517/7323/6233/330/7189/7311/1147/7099/7316/7335/7322/329/148022 19 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5693607 Processing of DNA double-strand break ends 55/3952 98/10654 9.237930473795482e-5 2.1421511566113396e-4 8.733866259383129e-5 83990/9156/1763/7486/5982/472/6613/4683/84126/8900/8924/672/6117/7334/83695/7314/6118/51588/51720/63967/5531/116028/890/9656/5985/5984/6233/7158/6047/5884/5810/80010/580/11073/641/6119/3364/10524/144715/1111/7329/7311/5983/1017/5883/10111/51548/545/7336/7316/7341/5932/9025/79184/7156 55 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-432722 Golgi Associated Vesicle Biogenesis 35/3952 56/10654 9.66715211853384e-5 2.237945715440584e-4 9.124434806616151e-5 27131/1176/5286/1174/1785/7037/3482/408/6456/3312/1362/25977/10618/6643/8301/2495/152503/6844/1213/2580/1211/8907/9685/9026/9829/51429/64746/8673/6272/2804/7163/5878/6845/375/4952 35 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-383280 Nuclear Receptor transcription pathway 33/3952 52/10654 9.886932898956136e-5 2.2850166050998458e-4 9.316349767297315e-5 7068/6097/4929/5469/9612/8856/2101/7067/5914/8431/7421/10062/7025/2516/5465/2099/7101/2494/5467/5241/7182/3172/2908/9971/367/6095/5468/2100/9611/3164/6256/7376/9975 33 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8852135 Protein ubiquitination 46/3952 79/10654 1.0357585982279991e-4 2.38981510454932e-4 9.743628708631992e-5 11065/7321/56852/65264/8239/55236/56254/3093/7347/7328/10670/7334/7332/7314/90268/79139/10477/92912/7323/29089/7324/6233/23168/7874/123169/9646/7326/5591/7317/8915/5111/118424/7327/7311/5195/3105/997/7319/7320/7336/7316/54926/7415/7322/55284/27338 46 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1181150 Signaling by NODAL 16/3952 20/10654 1.1086105161289401e-4 2.549437097521685e-4 1.039443112020512e-4 130399/4089/4088/10589/10637/7044/91/93/92/8928/4838/4087/2309/55997/5045/6997 16 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-622312 Inflammasomes 16/3952 20/10654 1.1086105161289401e-4 2.549437097521685e-4 1.039443112020512e-4 834/4790/7295/29108/10628/5970/598/4791/351/3326/4210/114548/9447/596/58484/22861 16 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-354194 GRB2:SOS provides linkage to MAPK signaling for Integrins 13/3952 15/10654 1.125899568572347e-4 2.576399506996689e-4 1.05043608409247e-4 5908/2244/3690/2885/7094/6714/2335/2266/2243/5747/6654/7450/5906 13 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-372708 p130Cas linkage to MAPK signaling for integrins 13/3952 15/10654 1.125899568572347e-4 2.576399506996689e-4 1.05043608409247e-4 5908/2244/3690/9564/7094/6714/2335/2266/2243/5747/7450/1398/5906 13 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 13/3952 15/10654 1.125899568572347e-4 2.576399506996689e-4 1.05043608409247e-4 3654/7334/7314/54106/6233/51311/3665/7189/7311/51284/4615/7316/7335 13 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 44/3952 75/10654 1.1422695043459892e-4 2.60955977226411e-4 1.0639560133970607e-4 23165/8683/6431/348995/57122/23511/23279/23225/9972/8021/55746/7919/6432/8563/10762/11338/79902/9883/10250/26097/57187/6396/129401/4928/5903/55706/7175/6428/4927/10482/8086/6426/22916/10921/9631/79023/23636/4686/53371/7307/9688/10189/9775/8480 44 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5205647 Mitophagy 21/3952 29/10654 1.1719183939174052e-4 2.6728976176539835e-4 1.0897797872743307e-4 9927/65018/1459/9140/8878/1460/9474/1457/84557/7314/6714/55669/6233/9804/51001/7416/7311/10452/7316/56993/81631 21 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-72172 mRNA Splicing 96/3952 191/10654 1.2234872731683736e-4 2.7859406925096245e-4 1.135869116418611e-4 6633/8683/6431/4904/51639/51585/23450/5431/9092/5435/6625/5433/3190/22938/988/3181/5439/1660/9410/6638/3312/10291/6432/6627/11051/8106/55749/5438/11338/1655/9343/3185/6626/24144/10236/10250/4670/55660/2521/3191/6636/23524/10914/3188/56259/5725/1994/7536/2963/6635/5434/220988/6632/24148/5436/10523/6428/27258/6637/5093/2962/23658/5094/6426/5432/22916/11100/10921/22827/23451/5440/5430/3184/25804/29894/51503/3178/5441/3183/10594/4686/10713/7307/5437/10189/10949/57794/27316/3187/6634/51593/9775/3192/10992/55339/6628 96 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9018519 Estrogen-dependent gene expression 78/3952 150/10654 1.2703092866415166e-4 0.00028878225845254773 1.1774078666778122e-4 3725/7039/27327/10274/5431/5435/5433/5469/4609/1387/8312/5439/192669/10499/1386/4343/904/7392/6387/5438/865/1655/6667/2099/2494/8850/595/1025/2353/26523/2957/2963/3838/5434/5241/5436/200845/5885/2962/10524/8243/4602/3326/6908/3169/5432/10728/7528/3727/27161/2354/596/5440/4435/9687/5430/5451/2625/57690/5441/10735/192670/7391/2958/5437/3320/2033/9126/3065/2066/861/23028/23112/10498/3276/8202/8648/2288 78 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5654726 Negative regulation of FGFR1 signaling 23/3952 33/10654 1.4271163156446157e-4 3.22608747221878e-4 1.315323451217236e-4 2885/5518/7314/5515/5594/8074/2260/6714/2248/2247/6233/2246/5781/673/9365/7311/5595/5516/2254/7316/10818/867/2255 23 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-210990 PECAM1 interactions 11/3952 12/10654 1.437600512888909e-4 3.22608747221878e-4 1.315323451217236e-4 5777/5335/5175/2534/3690/6714/7525/3685/3932/5781/4067 11 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-264870 Caspase-mediated cleavage of cytoskeletal proteins 11/3952 12/10654 1.437600512888909e-4 3.22608747221878e-4 1.315323451217236e-4 836/6709/840/2934/841/5339/28988/839/118/4137/7431 11 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-3371511 HSF1 activation 11/3952 12/10654 1.437600512888909e-4 3.22608747221878e-4 1.315323451217236e-4 7531/1915/6117/6118/10013/3297/6119/3326/10728/7415/3320 11 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-381033 ATF6 (ATF6-alpha) activates chaperones 11/3952 12/10654 1.437600512888909e-4 3.22608747221878e-4 1.315323451217236e-4 811/3309/4801/8720/468/7184/7494/4800/22926/4802/1649 11 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 11/3952 12/10654 1.437600512888909e-4 3.22608747221878e-4 1.315323451217236e-4 64135/3551/8737/841/8517/23586/8772/7706/843/1147/57506 11 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1250196 SHC1 events in ERBB2 signaling 17/3952 22/10654 1.4446554411231687e-4 3.22608747221878e-4 1.315323451217236e-4 4893/5578/2064/2885/3845/3265/1839/2065/2069/5580/6464/5782/6654/1956/1950/2066/5581 17 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-198753 ERK/MAPK targets 17/3952 22/10654 1.4446554411231687e-4 3.22608747221878e-4 1.315323451217236e-4 9252/1848/1432/6196/5518/6197/51231/5515/5594/5528/5519/5598/4208/6195/5600/5595/5516 17 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-389357 CD28 dependent PI3K/Akt signaling 17/3952 22/10654 1.4446554411231687e-4 3.22608747221878e-4 1.315323451217236e-4 5295/941/2534/2475/5290/9020/10000/3932/940/253260/5170/64223/8503/208/207/942/5296 17 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5205685 Pink/Parkin Mediated Mitophagy 17/3952 22/10654 1.4446554411231687e-4 3.22608747221878e-4 1.315323451217236e-4 9927/65018/9140/8878/9474/84557/7314/55669/6233/9804/51001/7416/7311/10452/7316/56993/81631 17 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9613829 Chaperone Mediated Autophagy 17/3952 22/10654 1.4446554411231687e-4 3.22608747221878e-4 1.315323451217236e-4 2670/1915/5116/3043/3920/3312/11315/7314/10013/6233/3326/7311/1080/7316/10226/3320/7431 17 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1632852 Macroautophagy 53/3952 95/10654 1.5170757142460512e-4 3.3823726598519504e-4 1.3790432276157398e-4 9927/5563/65018/1459/9140/8878/1460/53632/84938/9474/8655/1457/55054/2475/84557/10670/3312/7314/64422/25978/9821/51422/7249/10533/6714/55669/6233/9804/51001/57521/140735/7405/389541/7416/64223/5571/128866/6009/7311/5562/11345/55626/5564/5565/7248/10452/7316/8678/56993/10226/81631/10542/23710 53 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8953750 Transcriptional Regulation by E2F6 24/3952 35/10654 1.5258392121675525e-4 3.396459400161427e-4 1.384786599436814e-4 6045/80012/79813/11335/1869/1911/5928/10138/23512/672/6241/5888/7027/2146/8726/317/23429/6015/5931/1111/648/4149/5932/10919 24 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-948021 Transport to the Golgi and subsequent modification 93/3952 185/10654 1.53831864647536e-4 3.4187593599268397e-4 1.393878621985253e-4 6811/374/6711/11014/126003/2153/51807/10484/7039/347688/5861/7278/1780/8655/832/3998/7846/51226/375056/9632/3630/81027/6709/10652/54732/79861/10342/4253/2801/22872/1315/81562/8615/11316/8729/23423/10376/1314/10540/51128/6399/9334/378/6396/1453/26958/140735/84364/22820/84617/11258/6712/1783/10382/10802/11282/2157/7277/966/11196/1639/10282/6710/81876/347733/51143/5537/9871/10383/84790/7280/829/1778/9919/55291/51014/112714/1781/10121/2804/5265/10972/4905/11320/2683/9276/287/4248/375/288/10427/22818/372 93 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-76009 Platelet Aggregation (Plug Formation) 26/3952 39/10654 1.66601960366951e-4 3.696647331464775e-4 1.507177647173695e-4 5770/5908/2244/3690/2885/9564/7094/6714/2335/1445/2266/2243/2147/5170/6464/5747/1277/6850/6654/7450/7066/207/4352/1398/5906/1278 26 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8853659 RET signaling 27/3952 41/10654 1.7094669655556716e-4 3.7870009811113677e-4 1.544016162963068e-4 5295/2674/5335/5291/5578/2668/2885/8660/5290/5567/6714/5598/9260/5781/6464/5568/5566/8503/6654/5293/2549/10818/53358/5979/5296/2887/9046 27 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 14/3952 17/10654 1.761607081234918e-4 3.890098944094278e-4 1.5860507232940945e-4 4790/4792/1660/3551/11035/8737/8517/5970/4791/7098/1147/4615/4793/148022 14 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-4655427 SUMOylation of DNA methylation proteins 14/3952 17/10654 1.761607081234918e-4 3.890098944094278e-4 1.5860507232940945e-4 1912/6045/80012/1911/1789/57332/1788/84733/6015/8535/1786/7329/648/7341 14 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-449836 Other interleukin signaling 18/3952 24/10654 1.7662555212095523e-4 3.894172887238204e-4 1.5877117300095892e-4 5657/1435/836/282618/6382/9235/3588/6810/6844/6809/7297/6616/920/1440/163702/3716/1436/1441 18 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 19/3952 26/10654 2.0607316567644726e-4 4.5362222999141875e-4 1.8494847465831785e-4 83990/9156/1763/7486/472/4683/672/5888/116028/80010/580/641/10524/79728/10111/675/10635/5932/7156 19 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 12/3952 14/10654 2.652042655523939e-4 5.782868522013738e-4 2.3577608009119712e-4 5861/2801/5594/983/8615/9133/891/81876/5347/5595/5862/26003 12 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-180336 SHC1 events in EGFR signaling 12/3952 14/10654 2.652042655523939e-4 5.782868522013738e-4 2.3577608009119712e-4 374/4893/7039/2885/3845/3265/1839/2069/6464/6654/1956/1950 12 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8983432 Interleukin-15 signaling 12/3952 14/10654 2.652042655523939e-4 5.782868522013738e-4 2.3577608009119712e-4 6776/2885/3600/3718/6777/6464/6774/6654/3716/3561/3560/3601 12 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 12/3952 14/10654 2.652042655523939e-4 5.782868522013738e-4 2.3577608009119712e-4 9612/4204/814/801/805/5566/25942/8841/9611/2874/3065/808 12 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9005895 Pervasive developmental disorders 12/3952 14/10654 2.652042655523939e-4 5.782868522013738e-4 2.3577608009119712e-4 9612/4204/814/801/805/5566/25942/8841/9611/2874/3065/808 12 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-918233 TRAF3-dependent IRF activation pathway 12/3952 14/10654 2.652042655523939e-4 5.782868522013738e-4 2.3577608009119712e-4 1387/64135/7187/29110/23586/3661/3665/7706/9641/3456/57506/2033 12 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5654727 Negative regulation of FGFR2 signaling 23/3952 34/10654 2.8653875016575e-4 6.238280940128947e-4 2.5434391616758545e-4 2885/5518/2252/7314/5515/5594/8074/6714/2248/2247/6233/2246/5781/673/2263/7311/5595/5516/2254/7316/10818/867/2255 23 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic 54/3952 99/10654 2.8781132321045424e-4 6.256180405936165e-4 2.55073703792479e-4 11014/64837/51807/347688/5861/7278/10112/7846/51226/81027/11004/81930/54732/79861/29127/1315/3796/11316/56992/8729/23423/10376/1314/3835/3833/378/9493/26958/84364/22820/84617/10382/3832/7277/81876/9183/1062/146909/347733/10383/24137/84790/84643/7280/55582/51014/112714/10972/4905/9276/3799/375/22818/372 54 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2129379 Molecules associated with elastic fibres 25/3952 38/10654 3.043832177682711e-4 6.592752448673113e-4 2.6879624246039445e-4 3696/7042/7448/3688/4054/3693/2192/650/3690/3694/2200/7040/30008/7043/4238/2006/2335/3685/655/4052/652/4239/8425/27302/8516 25 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 16/3952 21/10654 3.0471901166653266e-4 6.592752448673113e-4 2.6879624246039445e-4 4790/4792/1660/3551/11035/8737/29110/8517/5970/3661/4791/7098/1147/4615/4793/148022 16 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9008059 Interleukin-37 signaling 16/3952 21/10654 3.0471901166653266e-4 6.592752448673113e-4 2.6879624246039445e-4 834/5777/5783/27178/59307/4088/29110/8809/10068/5781/5782/6774/5771/5778/25930/5775 16 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-109704 PI3K Cascade 28/3952 44/10654 3.0932211898757354e-4 6.681935043137474e-4 2.724323483921005e-4 5295/5291/9965/2264/2885/8660/2252/2323/54106/5290/3667/8074/2260/2248/2247/2246/5781/5170/2322/2263/208/9365/2549/2254/10818/2261/2255/5296 28 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 27/3952 42/10654 3.101264847182408e-4 6.688908187478828e-4 2.7271665377315063e-4 9070/5929/6657/324/6932/6659/7314/51176/8945/6662/7534/83439/6233/7514/331/4221/6934/7088/208/57680/7311/1487/1499/207/7316/64321/3065 27 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 10/3952 11/10654 3.573083003310531e-4 7.67080725131117e-4 3.1275012702856354e-4 64344/3091/1387/2056/405/768/10370/2034/7422/2033 10 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9020956 Interleukin-27 signaling 10/3952 11/10654 3.573083003310531e-4 7.67080725131117e-4 3.1275012702856354e-4 3717/3572/10148/7297/821/6774/6772/3716/246778/9466 10 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 10/3952 11/10654 3.573083003310531e-4 7.67080725131117e-4 3.1275012702856354e-4 627/4893/2885/3845/3265/4909/5781/6654/4915/10818 10 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-112409 RAF-independent MAPK1/3 activation 17/3952 23/10654 3.619954579330879e-4 7.759439676991653e-4 3.1636380176738356e-4 1844/1848/5605/3717/1847/3569/3572/5594/983/1843/3570/7297/5781/11221/3716/5595/5604 17 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5693538 Homology Directed Repair 71/3952 138/10654 3.7666812378247096e-4 8.061510384188786e-4 3.2867967009158933e-4 2237/83990/9156/1763/7486/5982/472/6613/4683/84126/8900/8924/2067/672/6117/7334/10714/83695/7314/6118/25/5888/51588/51720/63967/5531/116028/890/9656/5985/5984/6233/7158/6047/5884/5810/80010/7515/580/11073/641/5111/6119/3364/10524/144715/142/1111/7329/79728/51426/7311/3980/5983/10038/1017/5883/10111/675/51548/545/7336/7316/79008/10635/7341/5932/9025/79184/7156/5981 71 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-111885 Opioid Signalling 50/3952 91/10654 3.781811937920411e-4 8.081441202725309e-4 3.294922789637541e-4 5331/2770/817/5578/5582/2775/5530/4988/2782/5499/5518/814/2773/5515/818/84152/5567/5594/10681/5573/5528/5443/5519/2783/2771/5580/3710/115/801/805/3838/2781/5568/5566/23236/816/5577/1020/5141/5516/815/5321/5575/59345/3708/5173/5576/5534/1385/808 50 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 13/3952 16/10654 3.9518248259223196e-4 8.431773706921817e-4 3.43775851943764e-4 22938/1387/9794/2648/55534/3280/84441/8850/10046/4851/2033/3516/6928 13 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1368108 BMAL1:CLOCK,NPAS2 activates circadian gene expression 19/3952 27/10654 4.5367607984800584e-4 9.664970474062578e-4 3.940551032583584e-4 28999/5469/1387/2155/10499/23054/9575/5054/10135/5465/56938/406/8553/4862/79365/6256/10498/8648/551 19 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5654732 Negative regulation of FGFR3 signaling 20/3952 29/10654 4.872573413705861e-4 0.0010364478517055804 4.225750780323614e-4 2885/5518/7314/5515/5594/8074/6714/2247/6233/2246/5781/673/7311/5595/5516/2254/7316/10818/2261/867 20 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 21/3952 31/10654 5.129737333829932e-4 0.0010861593226661242 4.428431780488613e-4 857/5526/1452/324/8312/1855/5518/5515/1856/7471/5528/5519/2932/1857/5529/5516/1499/5525/139285/1455/5527 21 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5339562 Uptake and actions of bacterial toxins 21/3952 31/10654 5.129737333829932e-4 0.0010861593226661242 4.428431780488613e-4 5605/7296/1839/5606/84168/10015/6844/801/5608/805/6857/1938/6616/3326/6416/5604/5045/127833/3320/5609/808 21 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5654733 Negative regulation of FGFR4 signaling 21/3952 31/10654 5.129737333829932e-4 0.0010861593226661242 4.428431780488613e-4 9965/2264/2885/5518/7314/5515/5594/8074/6714/2247/6233/2246/5781/673/7311/5595/5516/2254/7316/10818/867 21 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-111471 Apoptotic factor-mediated response 14/3952 18/10654 5.208621061621855e-4 0.0011011833568634333 4.489686984142527e-4 55075/836/840/578/5594/708/331/317/1029/56616/5595/842/54205/581 14 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-4086398 Ca2+ pathway 36/3952 62/10654 6.14465305867871e-4 0.0012955078243512303 5.281976503360706e-4 5331/5578/27327/2775/5530/2782/192669/6932/4343/3845/51176/51701/8322/10681/83439/2783/7474/3710/26523/801/805/4772/6934/23236/27161/815/6885/1499/59345/57690/3708/192670/5534/23112/808/5592 36 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 11/3952 13/10654 6.183741451006952e-4 0.0012955078243512303 5.281976503360706e-4 2064/7314/2065/9101/10000/6233/10193/208/7311/207/7316 11 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-171007 p38MAPK events 11/3952 13/10654 6.183741451006952e-4 0.0012955078243512303 5.281976503360706e-4 4893/5898/1432/5603/3845/3265/9261/6714/5600/6300/7867 11 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-179812 GRB2 events in EGFR signaling 11/3952 13/10654 6.183741451006952e-4 0.0012955078243512303 5.281976503360706e-4 374/4893/7039/2885/3845/3265/1839/2069/6654/1956/1950 11 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-68884 Mitotic Telophase/Cytokinesis 11/3952 13/10654 6.183741451006952e-4 0.0012955078243512303 5.281976503360706e-4 10274/10112/9493/25836/23047/5885/8243/5347/23244/10735/9126 11 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-75205 Dissolution of Fibrin Clot 11/3952 13/10654 6.183741451006952e-4 0.0012955078243512303 5.281976503360706e-4 5327/5054/5340/3273/5328/302/5329/5055/6281/5270/5345 11 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-72202 Transport of Mature Transcript to Cytoplasm 46/3952 84/10654 7.033769729960885e-4 0.0014713714088728416 5.998998279516418e-4 23165/8683/6431/348995/57122/23511/23279/23225/9972/8021/55746/7919/6432/8563/10762/11338/79902/9883/10250/26097/57187/6396/129401/4928/5903/55706/7175/6428/4927/10482/8086/6426/22916/10921/9631/29894/79023/23636/4686/53371/7307/9688/10189/9775/8480/55339 46 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-202427 Phosphorylation of CD3 and TCR zeta chains 16/3952 22/10654 7.320615918111036e-4 0.0015290730090610869 6.234256215185972e-4 5788/3115/3113/3117/55824/3127/1445/3932/3120/3123/3122/920/5795/3119/915/917 16 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5693532 DNA Double-Strand Break Repair 82/3952 166/10654 7.373282452520467e-4 0.001537761160142782 6.269679088756144e-4 2237/83990/9156/1763/7486/5982/11200/472/6613/64421/4683/84126/8900/8924/2067/672/6117/7334/10714/83695/7314/6118/25/5888/322/51588/51720/63967/5531/116028/890/9656/5985/7157/5984/6233/7158/6047/5884/5810/8467/80010/3838/7515/580/11073/5591/641/5111/6119/3364/10524/144715/142/1111/7329/79728/51426/7311/3980/5983/10038/2547/1017/5883/10111/7520/675/51548/545/7336/7316/8314/79008/10635/7341/5932/9025/79184/7156/5599/5981 82 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-112043 PLC beta mediated events 32/3952 54/10654 7.488868831242754e-4 0.0015595260579604477 6.358417787751285e-4 5331/2770/817/5578/5582/2775/814/2773/818/5567/5594/5573/2771/5580/3710/115/801/805/3838/2781/5568/5566/23236/816/5577/815/5321/5575/3708/5576/1385/808 32 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-6783589 Interleukin-6 family signaling 17/3952 24/10654 8.121795149054088e-4 0.0016887984224604983 6.885480287095965e-4 9021/3717/3569/3572/3976/3570/7297/5781/3589/6774/6772/3716/1270/5008/867/3977/1489 17 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-74752 Signaling by Insulin receptor 43/3952 78/10654 8.631927148699996e-4 0.0017921893586762773 7.307020385493822e-4 5295/3643/4893/5291/9965/2264/3630/2885/8660/2252/3845/3265/2323/54106/5290/3667/9114/5594/8074/2260/2248/2247/529/2246/523/528/5781/5170/6464/2322/2263/208/9365/6654/2549/5595/2254/10818/2261/2255/5296/51382/2887 43 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8877330 RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) 9/3952 10/10654 8.813195549262465e-4 0.00182437088195612 7.438229203079781e-4 3558/4773/865/3458/1493/50943/861/8784/3559 9 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-937042 IRAK2 mediated activation of TAK1 complex 9/3952 10/10654 8.813195549262465e-4 0.00182437088195612 7.438229203079781e-4 7314/257397/23118/10454/6233/7189/7311/6885/7316 9 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-186712 Regulation of beta-cell development 26/3952 42/10654 9.324074358236867e-4 0.0019272528695819951 7.857694243000369e-4 2308/22938/1387/3630/9794/3170/2648/55534/3280/84441/2494/8850/10000/5080/3172/6927/10046/6514/208/4851/3171/207/2255/2033/3516/6928 26 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-165159 mTOR signalling 25/3952 40/10654 9.534645003224539e-4 0.00195626930151982 7.975998516294671e-4 5563/53632/6198/2475/10670/51422/7249/1981/5494/57521/6194/389541/64223/5571/6794/6009/208/1975/5562/5564/5565/7248/7529/207/10542 25 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-445355 Smooth Muscle Contraction 25/3952 40/10654 9.534645003224539e-4 0.00195626930151982 7.975998516294671e-4 140465/10580/3693/7169/5062/5829/4638/7094/7414/3672/800/302/801/805/10627/301/59/5058/4629/7170/7168/7171/10398/4637/808 25 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-2424491 DAP12 signaling 20/3952 30/10654 9.534876293224752e-4 0.00195626930151982 7.975998516294671e-4 5295/4893/5335/5291/567/2534/2885/3133/3845/3265/5879/5290/5336/3932/6464/10451/6850/22914/6654/5296 20 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5654696 Downstream signaling of activated FGFR2 20/3952 30/10654 9.534876293224752e-4 0.00195626930151982 7.975998516294671e-4 5295/4893/5335/2885/2252/3845/3265/5290/8074/2248/2247/2246/5781/6464/2263/6654/2549/2254/10818/2255 20 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8874081 MET activates PTK2 signaling 20/3952 30/10654 9.534876293224752e-4 0.00195626930151982 7.975998516294671e-4 3082/1280/1289/3688/3910/3918/284217/6714/2335/3909/5747/1277/3912/4233/3913/3915/1281/3673/3914/1278 20 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 24/3952 38/10654 9.693371331434347e-4 0.0019858543922363285 8.096621295313894e-4 7039/51741/2064/4609/1387/7022/3815/348/2099/3329/7020/4869/79047/10370/7329/1956/7528/4605/4435/7021/7422/1026/7341/2033 24 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-69190 DNA strand elongation 21/3952 32/10654 9.72483714332182e-4 0.0019864409988344127 8.099012976946038e-4 2237/1763/5982/5422/4174/84515/6117/10714/6118/5985/5984/4172/8318/4173/5111/6119/51659/5983/4176/4171/5981 21 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-73863 RNA Polymerase I Transcription Termination 21/3952 32/10654 9.72483714332182e-4 0.0019864409988344127 8.099012976946038e-4 5435/2965/2967/404672/2068/5434/9015/79101/4331/9013/2966/2071/6908/5440/902/9014/5441/51082/5437/2968/1022 21 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-4791275 Signaling by WNT in cancer 22/3952 34/10654 9.803429596458469e-4 0.001999554142361353 8.15247719745677e-4 27123/5526/1452/324/8312/5518/80351/5515/8322/5528/5519/2932/8658/6934/5529/5516/1487/1499/5525/139285/54894/5527 22 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-381119 Unfolded Protein Response (UPR) 50/3952 94/10654 0.0010197380032276086 0.0020768564317934727 8.467650034518499e-4 5393/2673/5526/811/3576/10130/3309/4801/6347/11340/9820/10488/8720/84699/7094/9114/468/3484/22872/1054/8894/7466/2931/64061/23016/148327/1968/6464/37/7184/7494/118/1051/84447/5611/4800/1639/10954/22926/90993/64764/4000/440/4802/1649/2081/30827/467/54512/7709 50 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-71291 Metabolism of amino acids and derivatives 167/3952 372/10654 0.0010229944606622453 0.0020804382223423993 8.482253522945027e-4 6158/6470/5689/6138/6227/6206/6234/6191/6128/5682/6132/6129/3620/5160/9255/6176/383/6224/6146/6154/143471/6202/5705/6169/5709/6175/6218/5695/6173/6167/5711/4946/5683/6192/6156/5699/6143/5702/6139/10295/3921/6208/5696/6170/5691/7296/5718/6203/1728/6147/5700/122706/5707/191/6222/23198/6134/6155/6231/9861/6142/2747/23521/5832/5698/8604/5692/5713/5162/5710/26227/6207/5719/6233/501/6188/6303/2744/6122/4942/6230/4967/6194/6166/3028/25828/1743/6136/6125/5706/4947/6232/6160/7299/5714/6193/6210/6229/6205/5688/5687/5708/55526/140801/6235/6181/4953/3034/5704/7311/6223/25873/5694/9045/6187/6168/6157/6137/440/6144/5684/27165/9349/4736/5720/51121/6159/9521/6217/6152/5690/51686/5717/9491/51065/6141/10197/6164/10213/10165/6209/11224/6165/6130/5715/6204/5701/6228/1152/23474/5685/7965/5686/445/6124/6520/5716/1738/6189/6135/6201/5860/5693/8942/5721/2875/6133 167 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 13/3952 17/10654 0.0011070032496156373 0.002247993441105439 9.165400866315989e-4 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355/7099/148022 13 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-112040 G-protein mediated events 32/3952 55/10654 0.0011591096676939357 0.0023503698225209877 9.582804475133883e-4 5331/2770/817/5578/5582/2775/814/2773/818/5567/5594/5573/2771/5580/3710/115/801/805/3838/2781/5568/5566/23236/816/5577/815/5321/5575/3708/5576/1385/808 32 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 14/3952 19/10654 0.001302332195540463 0.0026369379294543774 0.0010751184919453264 1869/4609/5928/990/7027/7153/5934/993/5111/1874/4149/1875/5933/3065 14 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-157858 Gap junction trafficking and regulation 29/3952 49/10654 0.001347550798278901 0.002724524103070442 0.001110828666933347 71/51807/1212/347688/1785/2697/7278/7846/81027/1759/79861/4646/1601/7082/6714/10376/1213/1211/1173/84617/10382/7277/8218/347733/10383/60/84790/7280/112714 29 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-111932 CaMK IV-mediated phosphorylation of CREB 10/3952 12/10654 0.0014250495455418637 0.002868686693851665 0.0011696058817719647 817/814/818/801/805/3838/816/815/1385/808 10 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-389359 CD28 dependent Vav1 pathway 10/3952 12/10654 0.0014250495455418637 0.002868686693851665 0.0011696058817719647 941/2534/2885/5062/5879/3932/940/998/5058/942 10 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 10/3952 12/10654 0.0014250495455418637 0.002868686693851665 0.0011696058817719647 5295/5291/3717/2056/8660/5290/2057/4067/5293/2549 10 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-445144 Signal transduction by L1 15/3952 21/10654 0.0014588804682774703 0.002932539754612744 0.0011956397165561413 1459/1460/8829/3688/1457/5605/3690/5879/5594/2260/3685/1956/5058/5595/5604 15 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 66/3952 132/10654 0.0015687969810747602 0.0031489292004520837 0.0012838648856376956 83990/9156/1763/7486/5982/472/6613/4683/84126/8900/8924/2067/672/6117/7334/10714/83695/7314/6118/25/5888/51588/51720/63967/5531/116028/890/9656/5985/5984/6233/7158/6047/5884/5810/80010/580/11073/641/5111/6119/3364/10524/144715/1111/7329/79728/51426/7311/5983/1017/5883/10111/675/51548/545/7336/7316/79008/10635/7341/5932/9025/79184/7156/5981 66 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-373753 Nephrin family interactions 16/3952 23/10654 0.001577927040675149 0.003158127751437726 0.001287615270564584 5295/6711/5291/2534/87/8976/6709/8826/8440/5290/8573/81/23607/4690/88/5296 16 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-389948 PD-1 signaling 16/3952 23/10654 0.001577927040675149 0.003158127751437726 0.001287615270564584 5777/3115/3113/3117/3127/29126/1445/3932/5781/3120/3123/3122/920/3119/915/917 16 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5654708 Downstream signaling of activated FGFR3 17/3952 25/10654 0.001662785985675786 0.0033184047903788315 0.0013529625836260935 5295/4893/5335/2885/3845/3265/5290/8074/2247/2246/5781/6464/6654/2549/2254/10818/2261 17 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 17/3952 25/10654 0.001662785985675786 0.0033184047903788315 0.0013529625836260935 5982/6117/10714/7314/6118/5985/5984/6233/7515/5111/6119/51426/7311/3980/5983/7316/5981 17 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 18/3952 27/10654 0.0017176216117222422 0.003417811654175171 0.0013934922283704615 356/836/26060/1612/8737/841/8797/1613/8772/8717/8743/8837/8795/7186/842/355/7099/148022 18 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5654716 Downstream signaling of activated FGFR4 18/3952 27/10654 0.0017176216117222422 0.003417811654175171 0.0013934922283704615 5295/4893/5335/9965/2264/2885/3845/3265/5290/8074/2247/2246/5781/6464/6654/2549/2254/10818 18 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle 22/3952 35/10654 0.0017199786510211984 0.003417811654175171 0.0013934922283704615 9761/811/7314/5700/79139/91445/11253/6233/23193/267/7841/821/56886/84447/2923/7311/55768/7316/5589/7415/51035/5887 22 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8964043 Plasma lipoprotein clearance 21/3952 33/10654 0.001744361272238668 0.003461311153056443 0.0014112276157359452 51599/949/163/10062/161/7436/348/3069/26119/1213/1211/1175/29116/1173/160/338/335/255738/6646/3949/7376 21 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-5654687 Downstream signaling of activated FGFR1 20/3952 31/10654 0.0017544219855760814 0.0034763083280530344 0.0014173421852089975 5295/4893/5335/2885/3845/3265/5290/8074/2260/2248/2247/2246/5781/6464/9365/6654/2549/2254/10818/2255 20 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase 11/3952 14/10654 0.001913330370111129 0.00378039243824233 0.0015413217625511529 5567/5573/801/805/5568/5566/5577/5575/5576/1385/808 11 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 11/3952 14/10654 0.001913330370111129 0.00378039243824233 0.0015413217625511529 4893/5753/9564/3845/3265/5829/5879/5921/387/1398/9844 11 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-3247509 Chromatin modifying enzymes 125/3952 274/10654 0.002080613235425227 0.0040992507574548085 0.0016713250028499772 9070/1810/4790/64769/51742/10474/9112/5929/79813/7403/84289/9612/6603/27097/55818/5928/1387/56950/3717/23512/1107/79084/57492/26610/6881/10499/1386/9575/3054/51230/10284/79723/54014/23774/84661/8464/9869/6314/2648/23186/55869/2146/1788/51147/6871/23569/86/83933/5970/8850/27154/57459/8289/6602/595/7994/3066/10419/8607/8726/6883/4791/55904/6595/1019/29943/23326/84148/7862/6597/93624/9219/5931/6599/8819/56970/11143/1108/2122/84444/10524/55578/54815/23210/55693/57504/58508/57634/6880/60/6601/6187/53615/4297/10196/8295/8841/55167/55250/11091/5978/6839/6598/117143/9611/2874/10856/29072/10933/2033/6605/3065/23028/23135/10498/9757/80854/9739/10902/3276/55729/9913/8648/64754/10919 125 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-4839726 Chromatin organization 125/3952 274/10654 0.002080613235425227 0.0040992507574548085 0.0016713250028499772 9070/1810/4790/64769/51742/10474/9112/5929/79813/7403/84289/9612/6603/27097/55818/5928/1387/56950/3717/23512/1107/79084/57492/26610/6881/10499/1386/9575/3054/51230/10284/79723/54014/23774/84661/8464/9869/6314/2648/23186/55869/2146/1788/51147/6871/23569/86/83933/5970/8850/27154/57459/8289/6602/595/7994/3066/10419/8607/8726/6883/4791/55904/6595/1019/29943/23326/84148/7862/6597/93624/9219/5931/6599/8819/56970/11143/1108/2122/84444/10524/55578/54815/23210/55693/57504/58508/57634/6880/60/6601/6187/53615/4297/10196/8295/8841/55167/55250/11091/5978/6839/6598/117143/9611/2874/10856/29072/10933/2033/6605/3065/23028/23135/10498/9757/80854/9739/10902/3276/55729/9913/8648/64754/10919 125 Hepatitis_B_virus_genotype_C_subtype_ayr R-HSA-205043 NRIF signals cell death from the nucleus 12/3952 16/10654 0.002317098553555433 0.004558710893609768 0.0018586536779675311 8878/23385/7314/6233/5663/7189/7311/4804/23421/7316/4803/5599 12 Hepatitis_C_virus_genotype_1a R-HSA-983169 Class I MHC mediated antigen processing & presentation 355/6120 371/10654 3.4461728445050294e-66 4.8591037107520915e-63 1.8282853827689843e-63 8454/8773/5689/127544/11065/221687/9666/84937/55070/5682/55819/93611/8916/3107/7321/51665/65264/122769/9021/8697/10484/26235/9817/55176/9039/154881/7174/6478/811/143471/5705/57674/10333/9690/8452/5709/9978/5695/23304/567/55236/54620/4734/7337/3693/84676/7704/3106/3093/10489/5711/23327/51465/10616/5683/929/3309/89910/25898/5699/7328/9632/7428/5702/22954/401036/83737/51529/140461/10075/29945/79176/8924/90135/56658/51434/6468/10425/25793/23295/3133/51666/90293/54461/29882/7334/92591/55182/84961/4591/3551/7332/5696/5691/9820/55658/7314/996/10324/283807/9354/5718/197131/8945/51088/64410/10952/146330/51320/5700/122706/5707/10477/148581/92912/23198/10533/140462/6892/51130/8517/6810/6477/7323/10517/9604/22872/64718/4008/7096/84861/11059/84085/27252/51444/26118/51433/9861/26249/55905/10134/143279/6502/5698/27246/5692/5713/9903/201456/26190/79654/5710/9040/7324/5719/64682/8925/51191/6233/3685/26091/6047/51128/131405/868/136371/6396/127247/1535/5930/11275/29116/26268/115290/51725/140459/23608/55585/64320/51132/1514/899/3135/23352/26224/4688/10293/114088/285231/653361/142678/246184/142686/151636/11146/255488/9616/91694/10802/10193/6890/140739/821/150726/390594/81559/2209/144699/5706/200845/79876/26263/9554/8881/7326/6049/57630/89890/22888/29927/7317/80196/140456/55958/84078/5714/26272/8651/64219/140458/5688/55336/5687/26270/63893/89122/118424/5708/55008/2923/10422/84727/695/90933/63891/9246/10393/9902/5704/9870/9520/4012/25847/7327/51343/7311/9871/7318/55175/9320/26232/57520/5694/8673/92369/3105/997/84261/7325/140691/23643/57154/1147/140460/5684/79754/6737/8065/5720/57531/84708/7319/54850/79791/26046/991/84231/10273/7320/5690/223082/5717/25897/9491/6500/26259/10197/7099/53339/154214/7336/4615/64750/51619/23480/23376/6891/54778/142689/7316/10213/114907/54926/7335/222235/25831/7322/5715/9867/5701/9341/23291/5685/5686/55521/114609/55294/135892/8453/80176/8139/126433/26267/948/142685/1520/5716/90025/84541/23194/55284/3134/80204/26234/27338/7097/23014/1536/90678/5693/5721/51676/10427/57542/4360 355 Hepatitis_C_virus_genotype_1a R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 299/6120 309/10654 2.1737870406806434e-59 1.5325198636798537e-56 5.766256150016023e-57 8454/5689/127544/11065/221687/9666/84937/55070/5682/55819/93611/8916/7321/51665/65264/122769/9021/8697/26235/9817/9039/154881/7174/6478/143471/5705/57674/9690/8452/5709/9978/5695/23304/55236/54620/4734/7337/84676/7704/3093/10489/5711/23327/51465/10616/5683/89910/25898/5699/7328/7428/5702/22954/401036/83737/51529/140461/10075/29945/79176/8924/90135/56658/51434/6468/10425/25793/23295/51666/90293/54461/29882/7334/92591/55182/84961/4591/7332/5696/5691/9820/55658/7314/996/10324/283807/9354/5718/197131/8945/51088/64410/146330/51320/5700/122706/5707/10477/148581/92912/23198/10533/140462/51130/6477/7323/10517/9604/64718/4008/84861/11059/84085/27252/51444/26118/51433/9861/26249/55905/143279/6502/5698/27246/5692/5713/9903/201456/26190/79654/5710/9040/7324/5719/64682/8925/51191/6233/26091/6047/131405/868/136371/127247/5930/11275/29116/26268/115290/51725/140459/23608/55585/64320/51132/899/23352/26224/10293/114088/285231/142678/246184/142686/151636/11146/255488/9616/91694/10193/140739/150726/390594/81559/144699/5706/200845/79876/26263/8881/7326/6049/57630/89890/22888/7317/80196/140456/55958/84078/5714/26272/8651/64219/140458/5688/55336/5687/26270/63893/89122/118424/5708/55008/10422/84727/90933/63891/9246/10393/5704/9870/9520/4012/25847/7327/51343/7311/7318/55175/9320/26232/57520/5694/92369/997/84261/7325/140691/57154/140460/5684/79754/6737/8065/5720/57531/84708/7319/54850/79791/26046/991/84231/10273/7320/5690/223082/5717/25897/9491/6500/26259/10197/53339/154214/7336/64750/51619/23376/54778/142689/7316/10213/114907/54926/7335/222235/25831/7322/5715/9867/5701/23291/5685/5686/55521/55294/135892/8453/80176/8139/126433/26267/142685/5716/90025/84541/23194/55284/80204/26234/27338/23014/90678/5693/5721/51676/57542 299 Hepatitis_C_virus_genotype_1a R-HSA-5683057 MAPK family signaling cascades 284/6120 294/10654 7.260394243996545e-56 3.4123852946783765e-53 1.283943403148863e-53 2308/5689/3725/5897/2674/4893/6711/2250/1437/71/5682/1844/1850/1848/5526/817/84292/7039/27327/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/22866/5605/4609/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/192669/4296/5894/1847/3563/1741/9542/1739/2885/6709/8660/8826/5518/2252/1740/4140/4343/2253/3845/5623/3265/4763/3569/5062/5696/5691/2323/7314/3572/5879/5515/5923/5718/818/10156/57554/1839/3667/8823/8831/2065/5700/3815/122706/5707/5567/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/3337/4902/2260/5528/2902/10125/983/3718/2249/25780/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/80824/1445/5710/8555/896/5719/2906/6233/51332/2266/2246/7514/2251/5154/115727/2243/1843/3570/255324/26523/369/801/200734/7297/5781/8682/4747/1846/11221/28956/805/22821/9462/3562/6464/6712/2904/5747/283455/3674/7010/5568/2322/2675/3315/409/5706/1438/673/2676/8315/221002/2263/4233/5597/84078/5714/64926/5566/6710/5688/5159/5687/5708/3084/5063/5529/816/998/9693/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/5058/5924/7529/5595/25759/5516/8822/5786/27161/815/5684/685/5720/2309/5604/3561/5525/153090/10642/10048/5690/57690/5717/9491/3568/8817/10817/10197/192670/5596/8550/54518/2254/7316/10213/152831/1950/3560/57731/26281/10818/5715/8437/10256/2261/5701/27040/5922/5685/2255/8649/53358/5686/2066/6708/27006/8556/5979/23112/1742/5527/5716/88/5906/5155/9048/4254/5896/399473/808/3559/8202/5693/5721/5245/5156/161742/284 284 Hepatitis_C_virus_genotype_1a R-HSA-5684996 MAPK1/MAPK3 signaling 251/6120 255/10654 2.5244184289254867e-55 8.898574961962341e-53 3.348176021522225e-53 5689/2674/4893/6711/2250/1437/71/5682/1844/1850/1848/5526/817/84292/7039/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/22866/5605/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/1847/3563/1741/9542/1739/2885/6709/8660/8826/5518/2252/1740/4140/2253/3845/5623/3265/4763/3569/5696/5691/2323/7314/3572/5515/5923/5718/818/10156/57554/1839/3667/8823/8831/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/4902/2260/5528/2902/10125/983/3718/2249/25780/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/80824/1445/5710/5719/2906/6233/51332/2266/2246/2251/5154/115727/2243/1843/3570/255324/369/801/200734/7297/5781/8682/4747/1846/11221/28956/805/22821/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/409/5706/1438/673/2676/8315/221002/2263/4233/84078/5714/64926/6710/5688/5159/5687/5708/3084/5529/816/9693/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/5924/7529/5595/25759/5516/8822/5786/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10817/10197/54518/2254/7316/10213/152831/1950/3560/57731/26281/10818/5715/8437/10256/2261/5701/27040/5922/5685/2255/8649/53358/5686/2066/6708/27006/5979/1742/5527/5716/88/5906/5155/9048/4254/399473/808/3559/5693/5721/5245/5156/161742/284 251 Hepatitis_C_virus_genotype_1a R-HSA-9607240 FLT3 Signaling 261/6120 267/10654 4.37453116206688e-55 1.2336177877028601e-52 4.641607801435174e-53 5295/5689/2674/4893/6711/2250/1437/71/5682/1844/5291/1850/1848/5526/817/84292/7039/5908/3082/143471/2064/5705/8452/6776/4684/5709/9978/5695/1852/2668/22866/5605/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/1847/3563/1741/9542/1739/2885/6709/8660/8826/9846/5518/2252/1740/4140/2253/3845/5623/3265/4763/5696/5691/2323/7314/5515/54106/5923/5718/818/10156/57554/1839/5290/3667/8823/8831/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/4902/2260/5528/2902/10125/3718/2249/25780/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/80824/1445/5710/5719/2906/6233/51332/2266/2246/2251/5154/115727/2243/1843/6777/255324/369/801/200734/5781/30849/8682/4747/1846/11221/28956/805/22821/5170/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/409/5706/1438/673/2676/5140/8315/221002/2263/4233/84078/5714/64926/6710/5688/5159/5687/5708/3084/5529/816/9693/208/6654/5704/10718/3716/7311/7450/1956/60/5536/2549/5694/5924/7529/5595/25759/5516/8822/5786/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10817/10197/54518/2254/7316/10213/152831/1950/3560/5289/3055/57731/26281/10818/5715/8437/10256/2261/5701/27040/5922/5685/2255/8649/53358/5686/2066/6708/27006/5979/1742/5527/5716/88/5906/5155/9048/4254/5296/399473/808/3559/5693/5721/5245/5156/161742/284 261 Hepatitis_C_virus_genotype_1a R-HSA-449147 Signaling by Interleukins 414/6120 461/10654 5.6776572206874386e-55 1.334249446861548e-52 5.020244279344684e-53 5295/729230/8454/6804/3605/7124/2308/834/1052/5689/3725/7291/5777/5897/9252/1437/4790/5682/5291/1511/26469/5657/5783/27178/1848/356/3593/5803/23529/9021/8878/6624/5908/3082/5743/3091/941/1265/143471/10538/3383/5705/11009/6097/6349/6657/3576/3313/3662/6776/3688/4985/5709/6175/9978/2920/5695/84868/1435/4792/3936/59307/7133/3606/177/4609/5898/5711/4988/1432/3558/3717/4088/836/5683/2534/84867/2162/5699/3181/5702/4001/3654/3563/2885/85480/51135/8660/282618/6196/3594/1154/50604/9846/6347/5518/282617/1386/6382/9235/7040/3588/6197/4282/7334/3600/3312/1399/3551/282616/3965/55801/3569/5062/5696/133396/5691/51231/4692/7314/3572/3596/5515/257397/3598/5718/54014/10148/8945/1326/5601/1072/3635/3592/5290/3667/6627/6283/5606/90865/64109/9049/11213/3587/7412/5700/122706/5707/27250/8767/1849/29110/1439/5594/4582/23198/23118/6367/4312/9987/8517/6778/7534/6810/332/5528/4313/3565/3934/3976/50615/3185/5970/5443/9261/3718/3627/8809/9861/149233/5519/5598/4208/3567/598/2247/5698/5692/5713/2335/595/6195/5710/3458/10454/7157/5478/1271/5719/6233/7525/6844/7409/2353/604/6809/3932/7076/302/51561/3570/8835/5600/6777/6773/7850/7297/5781/5608/4791/1846/59067/3557/56300/9655/3562/351/6464/3566/6597/5782/6351/7184/9180/3589/6775/50616/3684/9446/3595/54472/821/4318/5706/3726/58480/301/4478/1438/53833/3581/6616/79155/6774/920/6850/1440/5714/6772/8651/7867/5566/64127/8503/1901/3552/2889/5688/79923/5687/4067/29760/3636/5708/5602/29949/3656/57162/5771/998/9244/6648/116379/386653/7189/163702/112744/6654/5704/146433/7006/3716/84639/7311/2939/1270/5293/2185/6655/6356/5008/5694/246778/6416/1234/3586/3554/829/5595/3556/5516/6095/1147/5778/1845/596/5055/5684/2208/5720/6885/2309/5604/4215/3561/3578/3590/10392/207/5292/5451/7422/5690/3553/2625/1230/5717/2919/9491/6500/3568/25930/246330/10197/4615/3597/2357/1436/7316/10213/3560/6352/4314/7335/1441/4205/3055/1026/6348/4793/3146/6647/6364/5715/7132/5701/867/466/6950/23291/5685/3320/5686/4843/5306/9466/6288/2002/942/6285/5609/1398/58985/948/5716/1385/9173/53832/6363/3575/6845/5896/5296/6935/3687/5599/5784/7431/375/3977/3559/3574/3929/3162/1489/57161/1278/4170/5693/3689/5721/3601/5724/5034 414 Hepatitis_C_virus_genotype_1a R-HSA-5673001 RAF/MAP kinase cascade 245/6120 249/10654 7.090342007946247e-54 1.428197461600601e-51 5.3737328902329465e-52 5689/2674/4893/6711/2250/1437/71/5682/1844/1850/1848/5526/817/84292/7039/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/22866/5605/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/1847/3563/1741/9542/1739/2885/6709/8660/8826/5518/2252/1740/4140/2253/3845/5623/3265/4763/5696/5691/2323/7314/5515/5923/5718/818/10156/57554/1839/3667/8823/8831/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/4902/2260/5528/2902/10125/3718/2249/25780/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/80824/1445/5710/5719/2906/6233/51332/2266/2246/2251/5154/115727/2243/1843/255324/369/801/200734/8682/4747/1846/11221/28956/805/22821/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/409/5706/1438/673/2676/8315/221002/2263/4233/84078/5714/64926/6710/5688/5159/5687/5708/3084/5529/816/9693/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/5924/7529/5595/25759/5516/8822/5786/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10817/10197/54518/2254/7316/10213/152831/1950/3560/57731/26281/10818/5715/8437/10256/2261/5701/27040/5922/5685/2255/8649/53358/5686/2066/6708/27006/5979/1742/5527/5716/88/5906/5155/9048/4254/399473/808/3559/5693/5721/5245/5156/161742/284 245 Hepatitis_C_virus_genotype_1a R-HSA-5663205 Infectious disease 348/6120 383/10654 3.831672274033798e-49 6.753322382984569e-47 2.5410037185697823e-47 3839/6804/6158/6884/23165/6875/5689/51652/6138/2237/7852/6206/6234/6191/162/6128/5682/6132/6129/4057/27243/6874/6176/811/6224/6146/348995/6154/143471/6202/57122/5705/55048/3981/6169/5431/23511/5435/5709/6175/9978/5433/6218/5695/2960/292/567/51271/6173/23279/5605/6167/5711/23327/112755/29082/23225/5683/2965/6192/2534/6156/27183/5699/6143/5439/5702/6456/6873/3836/6139/30011/2885/163/9972/6881/2967/51616/3921/8021/7040/11198/904/55690/51497/5062/55746/6208/5696/6170/5691/92421/7296/7314/5879/5718/137492/3303/8945/6203/1839/161/402569/5606/6147/25978/5700/51160/122706/5707/2959/8027/6222/2060/7518/8106/23198/404672/84168/9636/10015/91782/5438/6134/3978/10762/79720/6155/1500/51534/4836/926/9397/6714/6231/9861/79902/6142/9883/23521/89853/83860/51510/999/5698/9146/6455/5692/5713/5710/2068/5902/6207/5478/5719/6233/6844/7514/1025/3932/1213/5610/1211/6188/6396/129401/6883/1175/6829/801/5608/8907/200916/6122/2957/940/805/25920/6230/60489/928/1173/4928/2963/3838/5434/5903/6857/6194/55706/7175/79643/6166/1938/5436/6136/6878/3841/6125/4869/821/5706/6232/160/6160/6616/293/5611/920/4233/4331/5714/6193/4927/6210/6229/8148/6205/2966/2962/10898/3840/5688/54457/8812/5687/5708/128866/140801/6235/6181/2071/5901/8086/5704/3326/7311/6223/25873/93343/6880/6908/7251/5694/3304/1104/2547/9045/6882/2961/6187/6416/5432/6168/22916/155382/1234/6157/6137/6877/5905/6144/3837/6917/81929/5440/164/5684/9349/8065/4736/2926/5720/902/79872/51121/9631/5604/1499/3159/6159/6217/3843/5430/6152/5690/5045/7520/5717/9491/6500/127833/6749/51065/6141/79023/5441/23636/10197/919/6164/4686/7316/10213/6872/53371/3055/6209/9688/11224/6165/6130/6879/5715/9525/6204/5701/2958/867/6228/5437/5685/3320/8815/5686/6124/6827/5609/2968/5716/6843/9844/6189/808/6135/6201/375/6161/138474/1022/5693/10254/5721/6457/8178/8480/6133/291 348 Hepatitis_C_virus_genotype_1a R-HSA-3700989 Transcriptional Regulation by TP53 333/6120 365/10654 4.6939746844178287e-48 7.353893672254598e-46 2.766974550814721e-46 6884/6875/834/5563/3725/9134/4436/83990/64769/5892/9156/57060/1763/7531/1459/79370/7486/6874/10971/9997/133383/9212/5982/27327/7295/7533/2810/55367/1460/11200/472/53632/79813/5431/7001/639/5435/1869/5433/28996/84289/1457/6790/25904/29117/4194/4514/1647/5928/1432/1387/4683/56950/51499/2965/84126/8738/5439/192669/1107/8900/6873/5371/8396/2475/672/55571/6881/2967/51616/5518/1386/55835/4513/4343/6117/11198/7159/57472/904/144455/85456/29883/51497/51230/637/64121/83695/7296/7314/5515/1263/27166/23368/9377/23774/6118/2176/1329/3622/7027/6446/2936/7832/51422/7249/404672/79837/898/117584/27244/7534/332/5438/5934/64065/1351/116028/890/10769/983/1643/8797/9656/5519/27154/5458/83860/57459/2821/2177/10000/5985/2877/900/7994/2068/54541/3066/7157/5984/6233/1121/1025/2353/604/63970/839/10419/5325/50484/5600/9167/6883/6829/79733/26523/7874/317/2744/5608/5884/5810/57521/26155/26013/5875/253260/28956/25920/5170/80010/2963/5434/83667/1820/7862/1029/389541/5457/9219/8445/7532/5436/1345/55240/204851/6878/4869/5931/4850/4292/580/11073/891/84987/80196/54971/4331/5366/641/5111/1108/8148/2966/246175/64223/2962/84883/6119/147923/3364/5571/10524/54457/4848/8812/144715/23019/1616/843/6794/54815/94241/1874/10128/25824/6009/1111/2071/55215/8626/208/79109/55004/7311/7161/5562/6880/6908/5983/1340/4697/5564/6882/5565/1020/53615/10397/8795/5432/665/7248/6877/7529/5516/1017/27161/27113/9891/6917/5440/27165/5305/8621/902/5883/25946/9540/5430/10111/8793/207/22974/57690/835/4849/1027/58484/3486/355/6749/545/5441/8794/192670/8550/9337/7316/6872/2539/1026/54205/5933/124446/5395/6879/112858/5876/143686/10848/5437/1350/9099/8649/28984/51755/2033/995/5728/3065/91875/6827/23112/10498/10542/5527/1349/2968/5932/8851/5300/7156/581/1327/3276/5052/138474/133746/1022/8178/10919/4193 333 Hepatitis_C_virus_genotype_1a R-HSA-5663202 Diseases of signal transduction 341/6120 377/10654 5.072464574136786e-47 7.152175049532868e-45 2.6910759424894103e-45 5295/8454/2308/27123/5689/4893/11052/2250/5335/71/79718/5682/5291/5526/817/1452/7039/9530/613/9372/182/5908/3082/941/55109/143471/23385/2064/5705/54845/5431/6776/5435/5709/9978/5433/5695/8546/9759/9612/22866/5605/4609/4089/22938/5037/3549/5711/1387/3717/10827/4088/2244/6907/5683/145957/324/2534/3690/408/9965/5699/6400/8312/11064/5439/2264/5702/4296/5894/6868/9794/9542/2885/2475/8660/79412/51009/8826/9846/5518/2252/6469/1185/4140/7040/2253/3845/388585/3265/80351/4763/5696/7750/5691/7314/5879/5515/5718/818/5947/8805/1839/26127/5290/3667/8823/2065/2648/9734/55869/55750/5700/3815/122706/5707/10956/8844/51564/7094/8322/55534/5594/3280/2069/8325/8074/7249/23198/84441/7414/10533/10013/23164/2260/5438/5528/89780/102/57085/2249/6714/2099/50846/5664/9861/2248/5519/9061/8850/399687/2932/7046/2247/5698/5880/10000/5692/5713/2335/1445/5710/3066/2280/5719/6233/2266/7409/2246/4040/27248/2251/5154/3932/2931/2243/7855/118788/6777/255324/369/801/5781/5663/940/1523/57670/253260/805/5170/2963/5434/7276/6464/22943/142678/572/283455/3674/5436/4303/4041/409/930/5706/6199/10046/9208/84447/673/8315/6774/2263/4233/8658/1024/5714/6772/6934/64223/10014/2962/8503/5688/5159/5687/29851/5708/3084/5529/816/4087/208/6654/5704/83464/10718/79109/56829/7048/7311/5293/7450/1956/11160/60/9444/55851/2549/51107/5694/4851/5432/22916/11140/7529/5595/5516/4000/1147/8822/27044/815/5440/5684/22906/8841/685/5720/8087/1487/2309/5604/1499/10018/5525/10142/842/139285/5430/23462/207/5690/5717/1027/9491/6500/8817/5441/10197/54518/2100/2254/4686/7316/10213/152831/1950/9611/1026/50852/26281/10818/7415/5715/80853/10256/2261/5701/867/5437/5685/2255/3164/3320/5686/2033/54894/391/55294/5728/3065/2066/27006/942/5527/1488/5716/1385/5906/5155/4254/5296/808/3516/9715/5693/5721/5245/5156/4193 341 Hepatitis_C_virus_genotype_1a R-HSA-9006925 Intracellular signaling by second messengers 284/6120 305/10654 1.0531336034622589e-45 1.3499258008016228e-43 5.079228097081134e-44 5295/1912/2308/5689/3725/6591/3643/2250/5335/5682/23035/5291/1822/1459/5526/9112/817/6045/5578/7039/5582/27327/80012/3082/1460/941/143471/2064/5705/5709/5695/107/1457/1911/4734/11060/5711/5928/5683/145957/2534/23512/9965/57332/5699/2444/2264/3630/5702/192669/1107/8975/3654/5371/9542/2885/8396/2475/51135/8660/5518/1386/2252/4343/2253/80351/64121/5696/814/5691/7314/5879/5515/5718/818/23396/1839/5290/3667/8823/90865/2065/23186/5700/3815/122706/5707/5567/2146/51564/5594/2069/84232/8074/7249/23198/79837/112/8395/100532731/2260/5573/5528/111/2249/6714/2099/9861/7101/81847/2248/5519/2932/84733/57459/2247/5698/5880/10000/5692/5713/5710/3066/7157/5613/5719/6233/5580/7409/2246/2251/5154/3932/2931/3710/118788/331/8726/196883/8394/115/255324/26523/7874/801/5781/57521/23608/940/6015/253260/28956/805/5170/3838/572/23239/389541/9219/8535/4303/5568/930/5931/5706/6199/113/2263/4233/8658/5714/10645/1108/2122/64223/5566/84254/10014/8503/5688/5159/5687/29851/5708/3084/54815/6009/5529/816/7189/208/5577/5704/10718/79109/55004/57504/7311/5293/1956/648/2549/5694/23466/53615/109/5595/3556/5516/1147/8822/27161/815/5684/8841/685/5305/5720/2309/5468/5525/5575/842/5978/8870/10273/207/5690/57690/5717/1027/9491/8817/114/10197/108/192670/4615/2100/2254/7316/10213/152831/1950/1026/50852/10768/26281/57167/10818/5715/1958/2261/5701/5576/5685/2255/8649/3164/5686/391/5728/6615/3065/2066/27006/23028/942/5987/23112/10542/5527/5716/1385/9173/5155/4254/5296/5581/808/5693/5721/5156/4193 284 Hepatitis_C_virus_genotype_1a R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 410/6120 473/10654 4.9225087783161895e-45 5.783947814521523e-43 2.176267038834526e-43 5295/3675/5777/627/3643/9252/4893/857/2250/2670/5335/71/5579/5770/5291/26469/1848/256076/5578/7039/1785/5908/3082/51741/23385/2064/1280/1289/54845/5431/8829/6696/6776/5435/3688/10312/5433/5753/7423/4734/10413/5605/3910/8569/1290/5898/1432/3717/55824/145957/2534/9475/3690/9965/5439/2264/5603/3630/6456/83737/6868/7072/4145/9542/30011/2885/2475/8660/6093/163/7073/6196/9846/1759/5518/8440/2252/9564/2253/6197/3845/1285/3265/1399/3071/8877/5062/23769/4486/10252/51231/56034/2323/5829/7314/5879/5515/6387/5607/54106/255631/26999/1839/3918/161/5290/3667/5899/8823/23768/6678/2065/5340/526/3815/5567/8027/10006/537/9550/1849/1284/2060/9114/5594/2069/8074/284217/9101/23118/5921/6778/2260/5438/348/5528/9306/1500/3185/1298/11059/102/9261/2249/6714/2099/5664/2248/1447/5519/5598/4208/4670/2567/2566/4909/2321/2247/4914/529/10810/10000/9146/6455/2335/64759/6195/3909/3728/8471/1445/3925/6233/7525/7410/5580/2324/7409/2246/23191/3685/1292/2251/5154/57610/3932/1213/3791/1729/3710/1211/29924/1293/1535/5600/6777/255324/1175/523/6300/528/801/200734/5781/30849/5663/2554/5725/1302/1291/10787/1846/253260/805/25920/5170/1286/4908/1173/4688/1287/2963/5434/5800/5590/6464/85440/653361/5241/2904/6461/5747/5782/7424/135/5436/10019/10193/5568/2322/7074/3315/2241/10451/4318/382/1277/160/3912/1793/673/5140/527/6774/2263/4233/10152/6772/8651/26052/7867/64223/5566/5802/2962/1003/8503/5795/2889/10163/5159/4067/3084/23767/55845/5063/5771/1111/5796/998/7058/3481/3913/208/6654/83464/5867/10718/79109/7006/5900/7311/2185/387/53834/1956/60/55851/2549/51107/5058/1020/5432/3480/22916/11140/53916/4916/7529/63916/5595/25759/5516/8822/1845/10253/9402/5440/1282/8065/685/85301/23543/558/4915/1495/5604/1499/4690/1299/5430/10048/10273/207/7422/10458/5045/3178/8817/10817/5441/58513/2254/4686/7316/152831/1950/9611/51072/9047/4205/5289/57498/3915/1301/10768/26281/10818/1281/1297/8936/3673/2261/6014/867/5437/466/245972/2255/53358/3320/4846/4803/2002/2066/3914/27006/6285/1742/200958/1398/3187/1385/9844/5228/5906/3479/5155/23163/50509/4254/8851/5296/5581/581/808/10076/7059/131873/1536/7057/1278/11033/10254/6457/51382/5156/161742/9296/2242 410 Hepatitis_C_virus_genotype_1a R-HSA-1257604 PIP3 activates AKT signaling 249/6120 264/10654 5.5864225104972395e-43 6.059119799847007e-41 2.2798031945672947e-41 5295/1912/2308/5689/3725/6591/3643/2250/5682/23035/5291/1822/1459/5526/9112/6045/7039/27327/80012/3082/1460/941/143471/2064/5705/5709/5695/1457/1911/4734/11060/5711/5928/5683/145957/2534/23512/9965/57332/5699/2444/2264/3630/5702/192669/1107/8975/3654/5371/9542/2885/8396/2475/51135/8660/5518/1386/2252/4343/2253/80351/64121/5696/5691/7314/5879/5515/5718/23396/1839/5290/3667/8823/90865/2065/23186/5700/3815/122706/5707/2146/51564/5594/2069/84232/8074/7249/23198/79837/8395/100532731/2260/5528/2249/6714/2099/9861/7101/81847/2248/5519/2932/84733/57459/2247/5698/5880/10000/5692/5713/5710/3066/7157/5719/6233/7409/2246/2251/5154/3932/2931/118788/331/8726/8394/255324/26523/7874/5781/57521/23608/940/6015/253260/28956/5170/572/23239/389541/9219/8535/4303/930/5931/5706/6199/2263/4233/8658/5714/1108/2122/64223/10014/8503/5688/5159/5687/29851/5708/3084/54815/6009/5529/7189/208/5704/10718/79109/55004/57504/7311/5293/1956/648/2549/5694/23466/53615/5595/3556/5516/1147/8822/27161/5684/8841/685/5305/5720/2309/5468/5525/842/5978/8870/10273/207/5690/57690/5717/1027/9491/8817/10197/192670/4615/2100/2254/7316/10213/152831/1950/1026/50852/26281/57167/10818/5715/1958/2261/5701/5685/2255/8649/3164/5686/391/5728/6615/3065/2066/27006/23028/942/5987/23112/10542/5527/5716/1385/9173/5155/4254/5296/5693/5721/5156/4193 249 Hepatitis_C_virus_genotype_1a R-HSA-8951664 Neddylation 220/6120 234/10654 2.0516086817839594e-37 2.0662630295109874e-35 7.774517109918162e-36 8454/5689/56995/5682/64344/80344/93611/55884/7321/51665/122769/9021/4738/26235/9817/9039/154881/5929/3091/143471/5705/140825/8452/5709/9978/5695/54620/7704/10980/10489/5711/7347/5683/23113/5699/10987/7428/5702/401036/140461/79176/90135/6468/26094/25793/1154/51666/90293/54461/92591/84961/5696/5691/9820/7314/51514/10324/283807/5718/51397/54165/8945/51088/64410/23363/23038/146330/5700/122706/5707/23198/140462/51130/28991/332/7323/9306/10517/4008/84861/84085/79016/27252/1643/26118/9861/122416/26249/6502/90864/55832/5698/5692/10920/5713/9903/201456/26190/10238/5710/9040/5719/10116/6233/83987/136371/8835/127247/11275/54939/26268/115290/54951/51725/140459/55208/10537/8451/899/26224/23412/9655/149951/285231/142686/9616/140739/5931/150726/390594/144699/5706/200845/26263/8450/89890/140456/55958/84078/5714/55527/26272/140458/5688/55336/5687/26270/1161/5708/1642/84727/5704/2873/7311/2034/55175/8533/26232/51667/5694/51122/92369/84261/150684/51138/56929/9318/140460/5684/79754/8065/5720/29099/11091/25879/54850/79791/5690/5717/9491/6500/28952/26259/10197/53339/142689/7316/10213/114907/64708/222235/7322/5715/5701/23291/170622/5685/5686/55294/8453/123879/80176/8139/23142/126433/26267/142685/5716/84541/23194/80204/26234/8883/23014/5693/5721/84259/51676/50813/57542 220 Hepatitis_C_virus_genotype_1a R-HSA-69275 G2/M Transition 189/6120 196/10654 5.301960439028638e-37 4.98384281268692e-35 1.8752196921196028e-35 114791/10844/8454/5689/440145/5682/7531/11190/203068/54801/51807/63943/51400/79441/143471/10381/5705/5116/7278/5048/5709/9978/5695/8655/6790/9702/5711/5928/7846/7840/113457/5683/5699/11064/5702/5520/8900/5518/55835/29922/23332/7465/5696/93323/5691/7314/5515/5718/8945/79861/4659/5700/122706/5707/1454/23198/993/890/983/9861/79959/5519/5698/5692/5713/80097/10376/5710/10540/7157/85378/5719/6233/7514/54930/54820/1453/27229/9793/4218/5500/84617/2305/11258/22981/8636/51512/7532/84962/55125/10382/121441/7277/5706/9133/286826/9814/653784/23354/728642/891/9738/4331/1639/5714/55722/4957/5566/5688/5687/91750/7283/5708/347733/22919/984/10426/22994/79866/1069/5577/5704/3326/55957/7311/10133/10383/5347/84790/80184/5694/22897/5108/4660/7280/10806/1778/5516/115106/1017/22822/22995/55559/5684/994/5720/4605/902/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/112714/1781/7316/10213/80321/1026/10121/5715/84131/9088/5701/23291/5685/3320/5686/2033/995/10733/4751/27175/80254/5716/23194/9662/55142/1022/8481/5693/5721/132660/55755 189 Hepatitis_C_virus_genotype_1a R-HSA-72163 mRNA Splicing - Major Pathway 178/6120 183/10654 1.1681668063070732e-36 1.0294469980581083e-34 3.873395199860296e-35 8449/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/5431/9092/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/22938/988/23020/6631/3181/5439/1660/9410/6638/3312/10907/10291/26121/10262/53981/6432/10084/6430/51340/6627/6936/83443/11051/9129/9879/8106/51690/27238/55749/5438/85313/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/10236/10250/4670/51362/10465/55660/25949/23283/2521/3191/10285/6636/23524/10914/8175/84950/3188/56259/5725/1994/10450/7536/2963/6635/5434/220988/6632/10283/24148/23350/5436/10523/6428/27258/6637/55110/5093/6429/57819/10181/2962/10898/10569/23658/6434/9295/84844/51692/10421/11193/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/51691/10946/27339/5430/79869/11325/57703/3184/25804/29894/11017/51503/3178/5441/3183/10594/4686/8189/23398/10713/10978/5546/7307/10772/5437/6629/10189/10949/51729/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/57461/84991/10992/55339/6628 178 Hepatitis_C_virus_genotype_1a R-HSA-453274 Mitotic G2-G2/M phases 190/6120 198/10654 3.363629127173772e-36 2.789833570185305e-34 1.0497022167774498e-34 114791/10844/8454/5689/440145/5682/7531/11190/203068/54801/51807/63943/51400/79441/143471/10381/5705/5116/7278/5048/5709/9978/1869/5695/8655/6790/9702/5711/5928/7846/7840/113457/5683/5699/11064/5702/5520/8900/5518/55835/29922/23332/7465/5696/93323/5691/7314/5515/5718/8945/79861/4659/5700/122706/5707/1454/23198/993/890/983/9861/79959/5519/5698/5692/5713/80097/10376/5710/10540/7157/85378/5719/6233/7514/54930/54820/1453/27229/9793/4218/5500/84617/2305/11258/22981/8636/51512/7532/84962/55125/10382/121441/7277/5706/9133/286826/9814/653784/23354/728642/891/9738/4331/1639/5714/55722/4957/5566/5688/5687/91750/7283/5708/347733/22919/984/10426/22994/79866/1069/5577/5704/3326/55957/7311/10133/10383/5347/84790/80184/5694/22897/5108/4660/7280/10806/1778/5516/115106/1017/22822/22995/55559/5684/994/5720/4605/902/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/112714/1781/7316/10213/80321/1026/10121/5715/84131/9088/5701/23291/5685/3320/5686/2033/995/10733/4751/27175/80254/5716/23194/9662/55142/1022/8481/5693/5721/132660/55755 190 Hepatitis_C_virus_genotype_1a R-HSA-913531 Interferon Signaling 189/6120 199/10654 4.736850309006856e-34 3.7105327420553705e-32 1.396124301602021e-32 80263/3839/3443/23165/5777/5335/960/5770/3107/817/9021/348995/3383/57122/11274/55223/3662/3115/23511/4684/567/4734/6672/3113/23279/3106/3459/3717/23225/3117/1973/11074/3836/5371/4599/684/9972/3133/3429/117854/8021/3127/91543/7334/4938/4261/55746/5696/7314/3445/818/402569/115362/7412/10410/85363/9830/163351/9636/3126/2634/3444/10762/2317/115361/103/3434/10475/3433/79902/23586/9883/3451/10437/3448/1981/10612/3458/3661/7324/1977/3439/51191/6233/5580/81603/10107/5610/10581/3452/4940/6396/3437/129401/6773/7297/5781/3430/3660/3446/8554/3135/3665/3120/4928/3838/5903/10379/55706/7175/3455/2316/2633/4600/3841/3123/23650/2209/8638/25820/1982/7706/23087/9470/3122/3394/3663/6772/8651/4927/3659/3840/25939/2635/3440/5771/3454/816/8086/10346/9246/3716/7311/7318/3125/7726/79097/3456/3105/1974/5595/3460/815/3837/81929/3441/6737/51447/9631/23321/4281/3119/4502/54739/79023/2537/23636/3449/51127/7316/53371/8519/3664/9688/6041/1958/4939/388646/7341/6059/55128/3669/3134/5300/9775/80128/5495/5724/8480 189 Hepatitis_C_virus_genotype_1a R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 224/6120 244/10654 1.3223607291129952e-33 9.522810123189018e-32 3.583050617459698e-32 8449/23165/6633/8683/6431/84271/55696/4904/51639/51585/9128/199746/23450/348995/57122/5431/9092/23511/81608/5435/6625/5433/51645/3190/1477/9416/65109/56339/22826/23279/8233/22938/988/23020/23225/6631/3181/5439/1660/9410/6638/57721/9877/9972/8021/3312/10907/10291/55746/26121/10262/7919/53981/6432/10084/8563/6430/51340/6627/6936/83443/11051/9129/9879/10081/8106/51690/27238/55749/5438/85313/10762/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/79902/9883/51213/10236/10250/4670/26097/51362/10465/55660/25949/23283/2521/1977/3191/10285/6636/23524/10914/57187/6396/129401/79228/8175/2733/84950/3188/84324/56259/5725/1994/10450/7536/4928/2963/6635/5434/5903/220988/6632/10283/55706/7175/24148/23350/5436/10523/6428/27258/6637/55110/5093/6429/57819/4927/10181/2962/10898/10569/23658/6434/9295/84844/10482/51692/10421/11193/8086/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/81929/5440/51691/10946/9631/27339/5430/79869/11325/57703/3184/25804/29894/9589/11017/51503/3178/79023/5441/23636/3183/10594/4686/8189/23398/10713/53371/10978/5546/7307/10772/9688/9984/5437/6629/10189/10949/51729/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/84248/6427/5356/57461/84991/8480/10992/55339/6628 224 Hepatitis_C_virus_genotype_1a R-HSA-2555396 Mitotic Metaphase and Anaphase 191/6120 202/10654 1.3507532089629812e-33 9.522810123189018e-32 3.583050617459698e-32 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/10274/147841/348995/143471/10381/57122/5705/7278/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/113457/5683/1060/5699/5702/5520/51529/4001/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/7444/5698/5692/5713/91687/119504/11243/10376/5710/7324/2010/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/26271/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/5708/347733/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/79023/55920/10735/10197/7443/112714/23141/1781/7316/10213/4085/55166/5715/5701/5685/8815/5686/79003/9126/9232/23592/5527/9700/5716/701/57551/5693/5721 191 Hepatitis_C_virus_genotype_1a R-HSA-68882 Mitotic Anaphase 190/6120 201/10654 2.2523281558254728e-33 1.512277476054246e-31 5.690092183138038e-32 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/10274/147841/348995/143471/10381/57122/5705/7278/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/113457/5683/1060/5699/5702/5520/51529/4001/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/7444/5698/5692/5713/91687/119504/11243/10376/5710/7324/2010/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/5708/347733/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/79023/55920/10735/10197/7443/112714/23141/1781/7316/10213/4085/55166/5715/5701/5685/8815/5686/79003/9126/9232/23592/5527/9700/5716/701/57551/5693/5721 190 Hepatitis_C_virus_genotype_1a R-HSA-68877 Mitotic Prometaphase 189/6120 200/10654 3.754336705821568e-33 2.406188525094732e-31 9.053520094421389e-32 114791/10844/55839/11130/440145/6249/9735/7531/1459/11190/203068/5526/54801/51807/9212/10274/1460/147841/348995/79441/10381/57122/5116/7278/1780/23122/5048/57405/8655/1457/23279/9702/2491/7846/7840/113457/1060/11064/11004/9184/5518/55835/29922/23332/25909/10726/81930/55746/93323/5515/79682/10403/79861/64151/25936/55869/1454/3619/64105/332/10051/5528/983/79902/3796/79959/5519/81565/80097/91687/11243/10376/23397/10540/85378/83540/7514/54930/54820/113130/6396/1453/27229/64946/9793/140735/220134/84617/4928/5903/11258/22981/55055/8636/80776/1783/401541/7532/55125/10382/79172/121441/7277/9133/79980/6232/23047/9814/653784/5885/23354/891/5501/9738/1639/55722/4957/5566/54821/9183/1062/699/7283/347733/22919/8243/10426/5529/22994/51143/1069/5577/10383/5347/84790/84643/80184/22897/5108/10592/7280/10806/1778/5516/115106/4926/5905/22995/55559/81929/54908/55143/5525/10142/1058/991/79019/348235/80152/1063/8379/95681/23244/23421/79023/55920/10735/112714/1781/80321/4085/55166/10121/84131/3320/79003/9126/9918/10733/4751/5527/27175/80254/701/57551/9662/55142/8481/55755 189 Hepatitis_C_virus_genotype_1a R-HSA-5633007 Regulation of TP53 Activity 156/6120 160/10654 1.1140441194478781e-32 6.829574819223948e-31 2.569694444859179e-31 6884/6875/5563/83990/64769/9156/1763/1459/7486/6874/133383/9212/5982/1460/11200/472/53632/79813/639/28996/84289/1457/6790/29117/4194/5928/1432/4683/56950/84126/1107/8900/6873/5371/8396/2475/672/6881/51616/5518/6117/11198/7159/51230/83695/7314/5515/1263/23368/23774/6118/3622/6446/51422/79837/117584/116028/890/983/5519/27154/5458/83860/57459/10000/5985/900/7994/3066/7157/5984/6233/10419/5600/6883/7874/5608/5884/5810/26155/26013/253260/5170/80010/7862/1029/5457/9219/8445/204851/6878/5931/580/11073/80196/54971/641/1108/8148/64223/6119/3364/5571/10524/54457/144715/1616/6794/54815/94241/1111/8626/208/79109/7311/7161/5562/6880/6908/5983/5564/6882/5565/1020/53615/6877/5516/1017/9891/5305/5883/25946/10111/207/22974/6749/545/8550/7316/6872/6879/112858/10848/9099/2033/3065/91875/5527/5932/8851/5300/7156/138474/133746/10919/4193 156 Hepatitis_C_virus_genotype_1a R-HSA-2467813 Separation of Sister Chromatids 180/6120 190/10654 4.8490006815565826e-32 2.8487879004144923e-30 1.0718843611861922e-30 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/10274/147841/348995/143471/10381/57122/5705/7278/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/113457/5683/1060/5699/5702/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/5698/5692/5713/91687/119504/11243/10376/5710/7324/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/5708/347733/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7280/1778/5516/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/79023/55920/10735/10197/112714/1781/7316/10213/4085/55166/5715/5701/5685/5686/79003/9126/9232/5527/9700/5716/701/57551/5693/5721 180 Hepatitis_C_virus_genotype_1a R-HSA-72172 mRNA Splicing 180/6120 191/10654 3.668610109868431e-31 2.069096101965795e-29 7.785176822626061e-30 8449/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/5431/9092/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/8233/22938/988/23020/6631/3181/5439/1660/9410/6638/3312/10907/10291/26121/10262/53981/6432/10084/6430/51340/6627/6936/83443/11051/9129/9879/10081/8106/51690/27238/55749/5438/85313/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/10236/10250/4670/51362/10465/55660/25949/23283/2521/3191/10285/6636/23524/10914/8175/84950/3188/56259/5725/1994/10450/7536/2963/6635/5434/220988/6632/10283/24148/23350/5436/10523/6428/27258/6637/55110/5093/6429/57819/10181/2962/10898/10569/23658/6434/9295/84844/51692/10421/11193/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/51691/10946/27339/5430/79869/11325/57703/3184/25804/29894/11017/51503/3178/5441/3183/10594/4686/8189/23398/10713/10978/5546/7307/10772/5437/6629/10189/10949/51729/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/57461/84991/10992/55339/6628 180 Hepatitis_C_virus_genotype_1a R-HSA-8856828 Clathrin-mediated endocytosis 141/6120 146/10654 4.54113004079509e-28 2.4626897528927222e-26 9.266111500245853e-27 5869/85439/71/8674/5286/4738/1212/7039/23208/1785/29763/950/8871/10094/554/54874/55738/10980/22848/7037/2017/3482/408/9322/10987/6456/185/8976/30011/2885/163/11037/1759/23149/3312/29993/9185/7314/9856/23396/1839/161/7018/25977/5868/10618/10093/8027/1856/9892/8322/2060/2069/1601/6453/55707/8301/1129/9146/6455/4074/10920/26119/29979/6233/90019/7474/6844/1213/2580/1211/29924/4036/255324/1175/85021/10109/6869/1173/6857/84251/23048/9026/29988/409/112574/382/160/338/8218/920/22905/26052/8867/10092/9829/2873/10097/7311/1956/60/8533/274/51429/8673/3092/50618/51138/9318/685/127833/1080/29978/58513/7316/1950/273/64708/10552/26130/3267/3949/867/9341/915/917/6572/115548/5878/1861/10096/143425/3575/6845/551/154/10254/6457/50813/4952/11252 141 Hepatitis_C_virus_genotype_1a R-HSA-162906 HIV Infection 209/6120 233/10654 7.248656995185174e-28 3.785409764152257e-26 1.4242975148434026e-26 6884/23165/6875/5689/51652/2237/7852/162/5682/27243/6874/348995/143471/57122/5705/55048/3981/5431/23511/5435/5709/9978/5433/5695/2960/292/567/51271/23279/5711/23327/29082/23225/5683/2965/2534/27183/5699/5439/5702/6873/3836/163/9972/6881/2967/51616/8021/11198/904/55690/51497/5062/55746/5696/5691/92421/7314/5879/5718/137492/8945/161/25978/5700/51160/122706/5707/2959/7518/23198/404672/10015/91782/5438/3978/10762/79720/51534/4836/926/9397/9861/79902/9883/89853/83860/51510/5698/5692/5713/5710/2068/5902/5478/5719/6233/7514/1025/3932/6396/129401/6883/1175/6829/8907/2957/940/25920/60489/1173/4928/2963/5434/5903/55706/7175/79643/5436/6878/4869/5706/160/293/920/4331/5714/4927/8148/2966/2962/5688/54457/8812/5687/5708/128866/2071/5901/8086/5704/7311/93343/6880/6908/7251/5694/1104/2547/6882/2961/5432/22916/155382/1234/6877/5905/3837/6917/81929/5440/164/5684/8065/5720/902/9631/3159/5430/5690/5045/7520/5717/9491/6500/6749/79023/5441/23636/10197/919/4686/7316/10213/6872/53371/3055/9688/6879/5715/9525/5701/2958/5437/5685/8815/5686/6827/2968/5716/9844/375/138474/1022/5693/5721/8178/8480/291 209 Hepatitis_C_virus_genotype_1a R-HSA-168254 Influenza Infection 148/6120 155/10654 1.1925676085151014e-27 6.005429742879618e-26 2.2596017845549294e-26 3839/6158/23165/6138/6206/6234/6191/6128/6132/6129/6176/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/23225/6192/6156/6143/5439/3836/6139/9972/3921/8021/7040/55746/6208/6170/3303/6203/402569/6147/6222/8106/9636/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/7514/1213/5610/1211/6188/6396/129401/200916/6122/6230/4928/2963/3838/5434/5903/6194/55706/7175/6166/5436/6136/3841/6125/821/6232/6160/293/5611/6193/4927/6210/6229/6205/2962/10898/3840/140801/6235/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/81929/5440/9349/4736/2926/51121/9631/6159/6217/3843/5430/6152/51065/6141/79023/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 148 Hepatitis_C_virus_genotype_1a R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 130/6120 134/10654 1.2827161225850003e-26 6.236654251189139e-25 2.346602271444066e-25 5295/8454/5689/3725/4893/5335/4790/5682/5291/7321/143471/5705/5530/5709/5695/4792/5711/5683/2534/5699/5702/2885/9846/3845/7334/3265/3551/5062/5696/5691/7314/5879/7294/257397/5718/8945/5601/4773/5290/5700/122706/5707/5336/5594/4214/23198/23118/10892/8517/10125/5970/9861/5588/5698/5692/5713/5710/10454/5719/6233/7410/7409/3702/2353/115727/3710/801/805/5170/6464/2205/4772/3937/4775/10451/5706/2206/6850/8915/5714/5688/5687/4067/5708/5602/695/7189/6654/5704/7006/7311/5694/5058/6416/997/5595/1147/9402/5684/5720/6885/84433/5690/5532/5717/9491/6500/10197/7316/10213/7335/10768/7462/7322/5715/5701/27040/23291/5685/5686/5534/5609/5716/10235/5296/808/5599/5693/5721/2207 130 Hepatitis_C_virus_genotype_1a R-HSA-6798695 Neutrophil degranulation 382/6120 480/10654 1.0663683674732124e-25 5.011931327124098e-24 1.885788270899997e-24 5869/8773/7130/9798/1727/5689/8804/5777/5806/4893/9218/4790/3240/960/7305/8288/1823/1511/5657/57826/1915/4057/3107/10875/203068/5175/5199/383/8836/2268/5211/5908/1460/1265/29108/23385/10394/54509/6280/5788/10577/10312/5709/10576/1509/5695/2896/4126/10562/8655/567/7133/154664/3106/3074/3417/3043/388698/1667/2548/1432/11010/3920/5476/8904/5683/929/201294/158747/2588/3482/4311/80142/2444/23200/5702/566/9961/51552/10075/56729/10487/6947/684/6709/6093/8826/9522/4282/2219/3608/2720/3312/3071/387263/2665/126014/4758/1654/967/2519/6037/5879/51316/2717/5718/3303/58485/2934/80331/57554/64333/56954/161/6283/56888/3579/5707/2358/3848/823/427/353189/5594/4831/4680/5787/6727/127829/7414/258010/10533/55754/4257/51209/326624/847/2517/25852/3934/22918/8895/5834/9545/1315/102/116844/4069/4973/9861/5870/410/411/28988/226/2821/5553/978/55832/968/5713/1/2495/3728/3614/10043/4125/5478/5719/374395/5328/728/5580/23191/3685/302/1729/9145/5236/25797/6036/1535/2040/230/317/23250/2990/401258/5663/7879/8907/5645/671/1508/28956/30/10450/7077/25801/1828/23352/23412/7276/5284/83858/4332/10159/1938/8635/51125/51646/1650/3684/79888/387921/3163/54472/3577/79169/2215/55860/1378/10549/2760/5864/4318/3958/963/79980/23317/5836/53917/6993/11240/10321/6616/5329/5611/84061/1116/527/6279/6515/54918/4048/6286/5337/10092/5795/6793/197/8694/140885/2171/3310/2352/1832/5708/55313/3615/820/51143/80301/4860/6386/10788/8993/6402/5473/3326/10857/55004/10097/3916/10383/387/81619/10396/196527/79930/5049/4317/51806/80184/1476/3304/2547/8673/10493/1075/53916/6282/114790/22931/1778/10694/2512/3837/10890/5036/8621/5005/29099/327/11333/5315/8876/23197/1991/10120/6317/7520/5717/2919/5004/1118/1604/25840/1512/2357/10213/4718/6278/5547/5799/2799/5768/1471/9588/29952/7415/3146/79792/4353/5701/6836/9342/8649/5265/3320/5686/388697/23593/391/1669/175/25798/5873/1088/150372/23071/51411/5878/2683/11031/22875/5646/948/1520/1675/719/93100/47/5906/89777/81567/10855/3687/353376/124583/7097/5660/2212/1536/8987/10970/3689/2207/5724/51382/2950/718 382 Hepatitis_C_virus_genotype_1a R-HSA-3858494 Beta-catenin independent WNT signaling 139/6120 146/10654 1.249088139545451e-25 5.681336376642213e-24 2.1376584799012134e-24 2788/5689/5579/5682/5331/5578/1212/81029/5582/27327/143471/5705/2775/5530/5709/5695/5881/5711/5683/5699/2782/5702/192669/57216/1855/6932/163/4343/5593/3845/5696/5691/4920/7314/5879/2787/5718/51176/2535/161/51701/5700/122706/5707/1856/8322/8325/23198/10681/7471/83439/2792/9861/8321/7481/5698/5880/5692/5713/2785/2783/23002/2784/5710/5719/6233/7474/1857/1213/3710/1211/7855/1175/26523/801/2791/7976/805/5145/1173/144165/4772/409/5706/160/5714/6934/5688/5687/4919/23236/5708/2786/5704/7311/387/5694/57154/27161/815/5684/5720/54331/6885/1499/59345/5690/5532/57690/5717/9491/50855/51764/94235/5330/10197/192670/64750/7316/10213/55970/54361/5216/5715/5701/2793/5685/5686/5534/23112/23513/5716/808/5693/5721/6259/8324/2790/5592 139 Hepatitis_C_virus_genotype_1a R-HSA-168255 Influenza Life Cycle 137/6120 144/10654 3.4963133610826726e-25 1.5405630747270527e-23 5.796519519689695e-24 6158/23165/6138/6206/6234/6191/6128/6132/6129/6176/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/23225/6192/6156/6143/5439/3836/6139/9972/3921/8021/55746/6208/6170/3303/6203/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/7514/1213/1211/6188/6396/129401/200916/6122/6230/4928/2963/5434/5903/6194/55706/7175/6166/5436/6136/6125/821/6232/6160/5611/6193/4927/6210/6229/6205/2962/140801/6235/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/81929/5440/9349/4736/2926/51121/9631/6159/6217/3843/5430/6152/51065/6141/79023/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 137 Hepatitis_C_virus_genotype_1a R-HSA-8957275 Post-translational protein phosphorylation 106/6120 108/10654 2.2326521968216376e-23 9.53951393187427e-22 3.5893355891486615e-22 56955/4240/3270/9210/10272/2153/7857/29106/91851/6696/51156/1435/265/11098/10130/2200/80341/375056/1114/720/10117/3956/3569/54972/2519/8720/7018/10618/11167/813/5179/8074/51246/348/4924/3484/102/8614/336/6694/4148/174/57104/721/2335/7466/116519/2266/51280/7076/2243/84141/3488/8542/4221/351/4052/7184/56975/334/3912/338/64856/335/5611/197/3053/3895/5624/1000/54757/8404/255738/3913/652/57719/147111/2719/3487/3371/54587/401138/3486/7425/6383/3827/3490/5589/2621/3915/5768/1471/1462/10232/462/3698/5265/1758/258/11320/5954/213/10970/5034/1356/718 106 Hepatitis_C_virus_genotype_1a R-HSA-168898 Toll-like Receptor Cascades 144/6120 155/10654 2.3788189464756077e-23 9.865102101560607e-22 3.7118413282467692e-22 8454/3725/9252/4790/7321/1848/1785/6280/10333/4792/59307/177/1432/2244/929/3654/51135/6196/1759/5518/7187/1386/6197/64145/7334/3551/51231/7314/5515/257397/54106/23098/11035/8945/1326/5601/6283/5606/11213/8737/8767/5336/1849/29110/5594/6271/4214/23118/841/8517/5528/7323/5970/7096/9261/5519/5598/4208/6195/10454/3661/6233/51311/10010/2266/2353/2243/8772/5600/5781/30849/5608/4791/671/1508/1846/1514/3665/351/81793/7184/653509/3684/8411/330/51295/7098/338/79155/6279/8651/26052/7867/64127/5602/3656/57162/695/7189/81622/7311/9641/6416/9450/51284/5595/5516/23643/1147/1845/4064/6885/5604/10392/6500/246330/7099/4615/7100/7316/7335/4205/5289/4793/3146/7322/329/466/23291/114609/6288/2002/6285/5609/948/1520/1385/5599/353376/7097/3929/57161/3689/148022 144 Hepatitis_C_virus_genotype_1a R-HSA-6807070 PTEN Regulation 132/6120 140/10654 3.464185395444272e-23 1.3955718307361208e-21 5.250975757305002e-22 1912/5689/3725/6591/5682/1822/1459/9112/6045/27327/80012/1460/143471/5705/5709/5695/1457/1911/4734/11060/5711/5928/5683/23512/57332/5699/2444/5702/192669/1107/8975/5371/2475/1386/4343/80351/64121/5696/5691/7314/5718/23186/5700/122706/5707/2146/51564/5594/84232/23198/100532731/9861/7101/81847/84733/57459/5698/10000/5692/5713/5710/3066/7157/5719/6233/331/8726/26523/7874/57521/23608/6015/28956/389541/9219/8535/5931/5706/8658/5714/1108/2122/64223/10014/5688/5687/5708/54815/6009/208/5704/55004/57504/7311/648/5694/23466/53615/5595/27161/5684/8841/5720/5468/5978/10273/207/5690/57690/5717/9491/10197/192670/7316/10213/57167/5715/1958/5701/5685/8649/5686/5728/6615/3065/23028/5987/23112/10542/5716/5693/5721 132 Hepatitis_C_virus_genotype_1a R-HSA-76002 Platelet activation, signaling and aggregation 224/6120 262/10654 3.741264087997728e-23 1.4653284344657767e-21 5.513441813891389e-22 5295/2788/2149/5777/5579/2153/5770/5291/7042/64805/2770/5175/3959/5578/5582/5908/3082/388/5583/29106/2769/5267/7423/5028/1432/3920/374354/2244/7114/3309/2534/3690/408/2162/2768/2782/87/2776/5894/10487/2885/51206/7040/9564/5874/54863/350/7043/2773/967/5879/5054/2787/5099/1072/5290/3699/7018/6678/5340/5336/813/7094/5594/10681/7414/10490/83706/7044/7534/6810/10125/7123/2792/6714/6694/3671/7273/22927/1191/9749/3273/146850/27154/226/5588/5880/2335/5294/1/2785/2783/2784/1445/8525/5478/2771/94121/22915/7410/5580/2266/7409/7873/5154/3932/7076/2243/3710/801/5781/2151/2791/2147/805/2814/928/5170/5590/351/6464/5747/51097/3937/7424/2316/3674/5552/409/6915/2157/7277/10451/334/1277/150/335/51706/308/6850/78991/8503/6403/197/4067/81/9948/998/3481/2786/6654/5473/8407/7450/387/29789/10916/5595/139322/7066/151/5321/54331/5005/59345/207/26090/7422/5004/51764/94235/5196/3827/54518/1950/55970/2812/2621/5216/2767/5768/346562/710/152/6647/4352/27040/2793/23533/1893/5265/7078/55664/391/5345/54676/2/1398/948/88/1675/2811/10235/5906/5341/3479/5155/5296/5581/51368/808/213/5660/2815/9630/7057/1278/9002/2207/5627/6814/2790/3700/10672 224 Hepatitis_C_virus_genotype_1a R-HSA-168273 Influenza Viral RNA Transcription and Replication 127/6120 134/10654 5.854475094165961e-23 2.231029698047028e-21 8.394467844835404e-22 6158/23165/6138/6206/6234/6191/6128/6132/6129/6176/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/23225/6192/6156/6143/5439/6139/9972/3921/8021/55746/6208/6170/6203/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/6188/6396/129401/200916/6122/6230/4928/2963/5434/5903/6194/55706/7175/6166/5436/6136/6125/6232/6160/5611/6193/4927/6210/6229/6205/2962/140801/6235/6181/8086/7311/6223/25873/9045/6187/5432/6168/6157/6137/6144/81929/5440/9349/4736/2926/51121/9631/6159/6217/3843/5430/6152/51065/6141/79023/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 127 Hepatitis_C_virus_genotype_1a R-HSA-69620 Cell Cycle Checkpoints 245/6120 293/10654 2.3866596522926874e-22 8.855763446664972e-21 3.3320677694058577e-21 5689/55839/11130/9134/83990/11065/6249/5682/9156/57060/9735/1763/7531/7486/7321/5526/10971/8697/9212/5982/7533/2810/147841/348995/11200/143471/472/57122/5705/1780/23122/5048/5709/4174/5695/57405/8655/84515/23279/4194/4998/5711/2491/4683/10926/5683/990/1060/165918/84126/5699/5702/8900/51529/29945/8924/11004/51434/55388/672/9184/5518/6117/29882/7334/23332/25909/7465/51230/10726/81930/55746/5696/83695/5691/7314/996/5515/5718/6118/79682/10403/23594/25936/5700/122706/5707/51588/51720/3619/23198/63967/898/64105/7534/332/5528/993/116028/890/983/51433/9861/79902/3796/9656/5519/81565/5698/5692/5985/5713/91687/119504/11243/4175/5710/7157/5984/7324/83540/5719/64682/6233/7514/7158/54820/6396/64946/9793/5884/5810/140735/4999/220134/4172/80010/4928/5903/8318/246184/55055/51512/1029/80776/1783/401541/7532/79172/4173/5706/9133/79980/6232/580/8881/11073/891/5501/641/5714/54821/6119/9183/3364/10524/5688/1062/699/5687/144715/5708/22919/5529/51143/1111/10393/5704/23595/7311/25906/5347/84643/5983/5694/4176/7529/1778/5516/1017/5905/81929/5684/5720/54908/55143/5883/5525/25946/1058/991/79019/10111/8317/348235/80152/5690/1063/8379/5717/1027/9491/23421/545/79023/55920/10197/7336/29086/1781/7316/10213/4085/1026/4171/55166/5715/9088/7341/5701/5685/5686/995/79003/5527/5716/701/5932/9025/79184/57551/7156/5693/5721/4193 245 Hepatitis_C_virus_genotype_1a R-HSA-418594 G alpha (i) signalling events 324/6120 406/10654 2.74880622682333e-22 9.9379917431305008e-021 3.7392667700916555e-21 729230/2788/10316/6000/1880/7852/50833/29899/2339/6385/5331/5726/338442/64805/2770/817/1237/2550/5578/50832/3354/2841/5582/4987/51289/259294/8644/2912/3576/6360/2775/5530/4985/2920/2921/1236/259295/107/6010/9568/2840/2831/5948/5367/4988/6370/58191/5475/6755/1524/643/221914/2782/5499/339403/4023/2914/8843/2847/2833/9290/5518/9170/6382/187/5143/6750/259296/259289/50835/2587/53829/814/2773/5515/2787/6387/818/4544/5947/4543/126006/10663/4889/9283/727/338398/344/117579/3579/84152/345/375790/23566/2358/5567/2916/259293/5594/5179/10681/112/8811/5573/348/56923/2832/5528/27199/2826/8786/6376/165140/27198/111/5443/4836/3627/2792/9397/54429/6714/336/3361/6346/10988/5519/134/5588/1129/338328/51083/2785/2783/2784/1233/2262/6366/5613/2861/2771/728/5332/183/10022/5580/6373/57121/3710/1132/1814/80835/4036/6357/50700/196883/9672/115/8698/801/9934/50840/2791/4647/50865/805/10803/2913/5145/3838/7276/351/11251/3352/8484/6351/6752/2781/1903/84539/6753/5568/3577/2918/5368/6754/131890/8862/301/56670/150/113/338/2868/335/2853/6751/186/53637/10645/5566/84254/10563/5540/1901/10287/5733/23236/256933/10850/624/4852/816/8601/2786/50838/5577/5473/4283/2239/11255/10874/83756/29967/2719/56477/1020/5141/259286/3350/129521/1234/109/9628/5516/151/57007/5533/815/26086/5321/9294/54331/283869/2817/5575/59345/63940/4986/6374/5539/259287/2852/50836/3339/1230/5532/846/4886/2919/51764/94235/114/5330/259290/6383/108/26020/5196/2779/3827/5173/2357/55970/2778/6352/140/10768/346562/152/55937/6364/80834/259292/3949/2793/5030/5697/5576/53630/3355/5534/3351/4035/6288/6372/50834/259285/79823/1385/7804/5144/719/6363/2917/1268/50831/2359/50839/808/5660/1815/1325/1232/1902/50837/10082/1269/59340/4887/2790/718/6003/623 324 Hepatitis_C_virus_genotype_1a R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 122/6120 129/10654 7.445903422077047e-22 2.624680956282159e-20 9.875619275596927e-21 8454/3725/9252/4790/7321/1848/1785/10333/4792/59307/177/1432/929/3654/51135/6196/1759/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/23098/11035/8945/1326/5601/6283/5606/11213/8737/8767/5336/1849/29110/5594/4214/23118/841/8517/5528/7323/5970/7096/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/671/1846/3665/351/653509/3684/330/51295/79155/8651/26052/7867/64127/5602/3656/57162/695/7189/7311/9641/6416/9450/5595/5516/23643/1147/1845/4064/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/7322/329/466/23291/114609/6288/2002/6285/5609/948/1385/5599/353376/7097/3929/57161/3689/148022 122 Hepatitis_C_virus_genotype_1a R-HSA-5357801 Programmed Cell Death 162/6120 181/10654 1.3251866690686256e-21 4.5573492765530785e-20 1.7147473201812254e-20 5689/2339/5682/4976/7531/55075/356/10971/10059/7533/2810/143471/5705/5709/1869/5695/8655/660/5711/836/5683/929/324/5699/9414/5702/90427/4001/3836/6709/6093/840/7159/26060/637/5062/5696/5691/7314/578/23368/5718/2934/11035/22985/219699/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/100506658/7082/5339/4836/8797/9861/28988/10134/22900/999/5588/598/5698/10000/5692/708/5713/5710/3002/7157/5719/6233/5580/1613/839/8772/331/8717/317/8743/140735/1828/5747/1029/572/7532/330/118/5706/1829/6774/5366/5714/8428/5688/5687/1832/56616/5708/8837/8626/197259/208/5704/7311/7161/5694/8795/3148/7529/5595/23643/4000/5533/27113/3837/596/5684/5720/7186/1499/10018/842/207/5690/5717/9491/355/10197/7099/9500/7316/10213/54205/3146/5715/79658/23604/5701/329/5685/5686/5534/4137/5716/1677/1630/581/5599/353376/7431/5693/5721/6304/148022 162 Hepatitis_C_virus_genotype_1a R-HSA-500792 GPCR ligand binding 364/6120 468/10654 3.192321812148944e-21 1.0675477502670545e-19 4.016753013322849e-20 729230/2788/10316/2532/2149/23620/1880/7852/7478/10161/50833/5726/338442/2740/64805/1237/2550/50832/3354/2841/4987/51289/259294/2150/3060/2912/6349/3576/6360/2798/5737/338557/4985/2920/2921/1236/259295/799/6010/9568/554/2911/2840/2831/5367/3549/5028/4988/6370/58191/6755/6866/1524/94233/643/5029/2782/2867/185/339403/2914/8843/64106/2847/2833/6347/9290/9170/6469/187/6750/259296/259289/50835/2587/53829/8111/2787/6387/4544/4543/2922/10663/4889/2535/9283/727/7476/1909/338398/117579/3579/6375/23566/2358/2916/7473/259293/1131/8322/6846/5179/27334/8325/10681/27202/5021/6865/6367/7471/2797/8811/56923/2832/2693/27199/2826/5727/6376/165140/27198/7201/89780/5443/7477/6354/3627/2792/54429/50846/3361/6346/7475/553/257313/134/9034/8321/3814/10800/5744/2863/7481/1129/51083/2785/2783/2784/2829/1233/7482/222545/6366/1241/2861/728/7474/183/10022/7479/6373/57121/4922/5731/2865/7855/1132/1814/80835/6357/552/2925/8698/9934/2151/6869/50840/2791/2147/1813/50865/7976/7480/10886/2837/80326/10803/146/2913/9340/3357/351/11251/8477/84432/3352/8484/2828/3062/1907/148/6351/6863/6752/135/1903/84539/6753/3577/594857/2918/5368/6754/6915/8862/10911/301/3061/5032/2642/56670/150/2853/29933/6751/5020/4935/887/4829/186/53637/60675/10563/5540/2864/1901/5733/256933/7200/7252/5729/10850/624/2641/1392/2796/4852/7483/4828/2786/680/50838/5473/4283/1910/6870/128674/11255/885/10874/83756/84634/147/6356/56477/51384/387129/259286/3350/129521/1234/151/57007/3356/84109/7472/9294/54331/4923/1128/283869/59345/4986/6608/6374/5539/259287/2852/1889/50836/1230/846/3358/4886/2919/7484/1908/51764/94235/259290/5196/3827/1604/5173/2357/55970/2778/6352/57105/1133/140/54361/3269/6348/886/2862/152/1906/6364/7253/80834/259292/5031/8620/2793/5030/5697/56413/3355/3351/6288/6372/5739/50834/259285/7434/719/6363/2917/1268/50831/2359/50839/347148/2846/5660/1815/1325/1232/4295/1902/551/154/50837/9002/1269/2915/59340/5724/4887/8324/2790/718/623 364 Hepatitis_C_virus_genotype_1a R-HSA-376176 Signaling by ROBO receptors 189/6120 218/10654 3.255642075282507e-21 1.0675477502670545e-19 4.016753013322849e-20 6158/5689/6138/7852/6206/6234/6191/6128/5682/6132/10298/6129/6176/5578/6224/6146/6154/26986/143471/6202/5705/6169/8829/23122/5709/6175/9978/6218/5695/65109/6173/6167/5711/1605/5683/6192/6156/5699/6143/9495/5702/6585/6139/10487/8440/3921/23332/5062/6208/5696/6170/5691/7314/5879/6387/5718/25/6092/6203/8861/6147/5700/122706/5707/5567/6222/23198/27/2935/6134/6091/22794/6155/4116/6714/6231/9861/6142/23521/5698/5692/5713/1981/5710/6207/5719/6233/6188/200916/6122/6230/1287/6194/2107/9423/6166/56924/6136/5568/6125/5706/6232/6160/55110/5714/6193/6210/6229/6205/5566/4650/5688/5687/5708/23767/5063/140801/6235/6181/998/9939/6654/5704/7311/6223/25873/387/6655/23708/5694/5058/9045/6187/6168/22916/6157/6137/10921/6144/55740/23032/5684/9349/4736/5720/51121/2817/6159/4690/6217/6152/5690/5532/5717/9491/51065/6141/23053/10197/6164/4686/7316/10213/5216/6209/11224/6165/6130/5715/6204/5701/6228/5576/5685/5686/7408/6124/8453/5716/23380/1630/6189/9775/6135/6201/6161/5693/5721/6133 189 Hepatitis_C_virus_genotype_1a R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 91/6120 92/10654 3.70512385084363e-21 1.1873237794748905e-19 4.4674220593904063e-20 6884/6875/5563/83990/9156/1763/1459/7486/6874/9212/5982/1460/11200/472/53632/28996/1457/6790/4194/1432/4683/84126/8900/6873/672/6881/51616/6117/11198/83695/7314/1263/6118/51422/116028/890/83860/5985/7157/5984/6233/5600/6883/5884/5810/26155/80010/8445/204851/6878/580/11073/641/8148/6119/3364/5571/10524/54457/144715/6794/94241/1111/7311/5562/6880/6908/5983/5564/6882/5565/1020/6877/1017/9891/5883/10111/22974/6749/545/8550/7316/6872/6879/112858/5932/8851/5300/7156/138474/4193 91 Hepatitis_C_virus_genotype_1a R-HSA-109581 Apoptosis 159/6120 178/10654 5.165844891919012e-21 1.618631399467957e-19 6.090259240999257e-20 5689/2339/5682/4976/7531/55075/356/10971/10059/7533/2810/143471/5705/5709/1869/5695/8655/660/5711/836/5683/929/324/5699/9414/5702/90427/4001/3836/6709/6093/840/7159/26060/637/5062/5696/5691/7314/578/23368/5718/2934/22985/219699/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/100506658/7082/5339/4836/8797/9861/28988/10134/22900/999/5588/598/5698/10000/5692/708/5713/5710/3002/7157/5719/6233/5580/1613/839/8772/331/8717/317/8743/140735/1828/5747/1029/572/7532/118/5706/1829/6774/5366/5714/8428/5688/5687/1832/56616/5708/8837/8626/208/5704/7311/7161/5694/8795/3148/7529/5595/23643/4000/5533/27113/3837/596/5684/5720/7186/1499/10018/842/207/5690/5717/9491/355/10197/7099/9500/7316/10213/54205/3146/5715/79658/23604/5701/329/5685/5686/5534/4137/5716/1677/1630/581/5599/353376/7431/5693/5721/6304/148022 159 Hepatitis_C_virus_genotype_1a R-HSA-69242 S Phase 146/6120 161/10654 6.3059352934923254e-21 1.9329062530052562e-19 7.27274917144195e-20 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/10274/5925/143471/5705/5709/5422/9978/1869/4174/5753/5695/84515/4609/4998/5711/5928/5683/990/5699/5702/8900/51529/29945/51434/157570/6117/29882/10714/7465/5696/5691/7314/996/5718/6118/23594/7027/5700/122706/5707/64785/23198/898/3978/91768/5934/993/890/51433/9861/2932/6502/5698/10000/5692/5985/5713/119504/595/4175/5710/5984/7324/5719/64682/6233/113130/23649/1163/5424/4999/4172/1019/8318/246184/4173/5706/286826/23047/8881/5885/4331/5714/5111/6119/5688/5687/91750/5427/5708/1874/8243/81620/10393/208/5704/55957/51343/23595/7311/25906/51659/5983/5694/4176/1017/5684/994/5720/902/207/5690/5717/1027/9491/6500/23244/10735/10197/4149/7316/10213/1026/5426/4171/5715/5701/5685/5686/9126/5716/5981/1022/5693/5721/132660 146 Hepatitis_C_virus_genotype_1a R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 100/6120 103/10654 8.649157452069868e-21 2.59474723562096e-19 9.762990718573827e-20 5295/3643/2250/5291/5526/7039/3082/941/2064/145957/2534/9965/2264/3630/3654/9542/2885/8396/51135/8660/5518/2252/2253/5879/5515/23396/1839/5290/3667/8823/90865/2065/3815/5594/2069/8074/79837/8395/2260/5528/2249/6714/2099/2248/5519/2247/5880/7409/2246/2251/5154/3932/118788/8394/255324/5781/940/930/2263/4233/8503/5159/29851/3084/5529/7189/10718/5293/1956/2549/5595/3556/5516/8822/685/5305/5525/8870/207/8817/4615/2100/2254/152831/1950/50852/26281/10818/2261/2255/391/2066/27006/942/5527/9173/5155/4254/5296/5156 100 Hepatitis_C_virus_genotype_1a R-HSA-202403 TCR signaling 113/6120 119/10654 9.400345956075681e-21 2.7613516245972314e-19 1.0389856056715228e-19 5295/8454/5689/5335/4790/5682/5291/7321/143471/5705/5788/3115/5709/5695/4792/3113/5711/3117/5683/55824/5699/5702/26191/3127/7334/3551/5062/5696/5691/7314/5718/8945/3635/5290/5700/122706/5707/8767/23198/23118/10892/8517/3126/5970/9861/5588/5698/5692/5713/1445/5710/916/5719/6233/3702/3932/3120/5170/3937/3123/5706/3122/920/8915/5714/5795/5688/5687/5708/5063/7189/7535/5704/7311/3125/5694/5058/997/1147/55740/9402/5684/5720/6885/4690/3119/84433/5690/5717/9491/6500/10197/919/7316/10213/7335/50852/7322/5715/5701/27040/23291/915/5685/917/5686/7408/5728/7454/5716/5296/5693/5721 113 Hepatitis_C_virus_genotype_1a R-HSA-8876198 RAB GEFs exchange GTP for GDP on RABs 89/6120 90/10654 1.112515379407697e-20 3.201319765234394e-19 1.2045279295842736e-19 5869/163486/116442/126003/7531/22878/1122/54453/10981/5861/163259/5866/23011/9610/60684/3257/414918/51762/51552/126432/201475/5874/79961/221960/2665/79090/22898/58485/5868/81846/51622/84079/51209/5872/9827/80006/5870/8408/9909/10000/51112/117177/83696/1121/23682/27095/6399/7109/4218/7879/2664/201627/27342/23258/5864/10260/57679/81876/259173/6305/51693/8567/208/79890/22879/54734/57589/84315/22931/51399/10890/207/122553/79958/57706/22930/55667/26130/27147/25782/9367/51560/11021/5873/5878/11031/338382/89781/160518 89 Hepatitis_C_virus_genotype_1a R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 104/6120 108/10654 1.2065402356268214e-20 3.402443464467636e-19 1.2802026921177223e-19 5295/3605/7124/2308/1052/7291/356/3593/9021/6624/3082/5743/3091/10538/3383/6097/6657/3576/3662/3688/4985/7133/3606/4609/4988/3717/2162/6347/7040/3312/3569/4692/3596/3598/3592/7412/4582/6367/4312/6778/332/4313/3565/3934/3976/5443/3718/149233/598/2247/2335/595/7157/2353/604/7076/51561/3570/7297/9655/3566/7184/3684/4318/3726/58480/301/6774/6772/8651/1901/3552/79923/112744/3716/6356/5008/3586/6095/596/2208/2309/3561/207/5292/5451/7422/3553/2625/3597/4314/1026/3320/4843/6288/948/6935/3687/7431/3929/3162/1278/4170/3689 104 Hepatitis_C_virus_genotype_1a R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 107/6120 112/10654 2.436064158958164e-20 6.735000910060807e-19 2.5341100848605054e-19 6158/6138/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/6202/6169/6175/6218/6173/6167/6192/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/200916/6122/1968/6230/8669/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6164/8661/9669/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 107 Hepatitis_C_virus_genotype_1a R-HSA-375276 Peptide ligand-binding receptors 175/6120 201/10654 3.6224140120301e-20 9.822314917235463e-19 3.695742230897106e-19 729230/10316/2532/2149/23620/7852/1237/4987/51289/2150/3060/6349/3576/6360/4985/2920/2921/1236/554/2831/5367/4988/6370/58191/6755/6866/1524/643/185/339403/64106/2847/2833/6347/187/6750/2587/6387/2922/10663/4889/9283/727/1909/117579/3579/6375/2358/6846/5179/27202/5021/6865/6367/8811/56923/2832/2693/2826/6376/7201/5443/6354/3627/6346/553/257313/9034/3814/51083/2829/1233/6366/2861/728/183/10022/6373/4922/6357/552/2925/2151/6869/2147/50865/10886/2837/10803/351/84432/8484/3062/1907/6351/6863/6752/84539/6753/3577/594857/5368/6754/8862/10911/301/3061/6751/5020/887/4829/186/60675/10563/5540/256933/7200/10850/624/4852/4828/680/5473/4283/1910/6870/128674/885/10874/84634/6356/56477/387129/129521/1234/57007/84109/4923/283869/4986/6374/5539/2852/1889/1230/4886/2919/1908/5196/3827/5173/2357/6352/6348/886/2862/1906/6364/8620/5697/6288/6372/719/6363/2359/347148/5660/1325/1232/4295/551/9002/4887/718/623 175 Hepatitis_C_virus_genotype_1a R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 106/6120 111/10654 4.082425051603058e-20 1.0860791175019456e-18 4.0864790983275904e-19 6158/6138/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/6192/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/200916/6122/1968/6230/8669/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6164/8661/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 106 Hepatitis_C_virus_genotype_1a R-HSA-199418 Negative regulation of the PI3K/AKT network 105/6120 110/10654 6.838154027155932e-20 1.7855179959796042e-18 6.718186412644424e-19 5295/3643/2250/23035/5291/5526/7039/3082/941/2064/145957/2534/9965/2264/3630/3654/9542/2885/8396/51135/8660/5518/2252/2253/5879/5515/23396/1839/5290/3667/8823/90865/2065/3815/5594/2069/8074/79837/8395/2260/5528/2249/6714/2099/2248/5519/2247/5880/10000/7409/2246/2251/5154/3932/118788/8394/255324/5781/940/23239/930/2263/4233/8503/5159/29851/3084/5529/7189/208/10718/5293/1956/2549/5595/3556/5516/8822/685/5305/5525/8870/207/8817/4615/2100/2254/152831/1950/50852/26281/10818/2261/2255/391/5728/2066/27006/942/5527/9173/5155/4254/5296/5156 105 Hepatitis_C_virus_genotype_1a R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 85/6120 86/10654 1.0007090605646198e-19 2.519642456064489e-18 9.480401626401662e-19 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 85 Hepatitis_C_virus_genotype_1a R-HSA-453276 Regulation of mitotic cell cycle 85/6120 86/10654 1.0007090605646198e-19 2.519642456064489e-18 9.480401626401662e-19 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 85 Hepatitis_C_virus_genotype_1a R-HSA-9010553 Regulation of expression of SLITs and ROBOs 152/6120 171/10654 1.2040913346820029e-19 2.9430035369008423e-18 1.1073339175797125e-18 6158/5689/6138/6206/6234/6191/6128/5682/6132/6129/6176/6224/6146/6154/26986/143471/6202/5705/6169/5709/6175/9978/6218/5695/65109/6173/6167/5711/1605/5683/6192/6156/5699/6143/5702/6585/6139/3921/6208/5696/6170/5691/7314/5718/6092/6203/8861/6147/5700/122706/5707/6222/23198/2935/6134/6091/22794/6155/4116/6231/9861/6142/23521/5698/5692/5713/1981/5710/6207/5719/6233/6188/200916/6122/6230/1287/6194/2107/6166/6136/6125/5706/6232/6160/55110/5714/6193/6210/6229/6205/5688/5687/5708/140801/6235/6181/9939/5704/7311/6223/25873/23708/5694/9045/6187/6168/22916/6157/6137/10921/6144/23032/5684/9349/4736/5720/51121/6159/6217/6152/5690/5717/9491/51065/6141/23053/10197/6164/4686/7316/10213/6209/11224/6165/6130/5715/6204/5701/6228/5685/5686/6124/8453/5716/6189/9775/6135/6201/6161/5693/5721/6133 152 Hepatitis_C_virus_genotype_1a R-HSA-202424 Downstream TCR signaling 95/6120 98/10654 1.2314695650861681e-19 2.9430035369008423e-18 1.1073339175797125e-18 5295/8454/5689/4790/5682/5291/7321/143471/5705/3115/5709/5695/4792/3113/5711/3117/5683/5699/5702/3127/7334/3551/5696/5691/7314/5718/8945/3635/5290/5700/122706/5707/8767/23198/23118/10892/8517/3126/5970/9861/5588/5698/5692/5713/5710/916/5719/6233/3932/3120/5170/3123/5706/3122/920/8915/5714/5688/5687/5708/7189/5704/7311/3125/5694/997/1147/5684/5720/6885/3119/84433/5690/5717/9491/6500/10197/919/7316/10213/7335/50852/7322/5715/5701/23291/915/5685/917/5686/5728/5716/5296/5693/5721 95 Hepatitis_C_virus_genotype_1a R-HSA-5620912 Anchoring of the basal body to the plasma membrane 95/6120 98/10654 1.2314695650861681e-19 2.9430035369008423e-18 1.1073339175797125e-18 79867/7531/11190/203068/54801/85302/79441/5116/5048/22832/8655/9702/132320/7846/7840/11064/84902/5518/55835/23332/93323/1454/54806/91147/983/79959/10540/117177/57545/26005/54930/54820/23322/1453/9793/4218/11258/22981/8636/54903/80776/7532/55125/10382/121441/7277/9814/23354/146057/9738/1639/55722/4957/5566/7283/22919/27077/22994/4867/1069/5577/10383/5347/80184/22897/5108/261734/57787/10806/9657/1778/115106/22995/55559/10142/51134/95681/1781/80321/8766/79598/10121/347240/84131/3320/79600/10733/4751/80254/26123/9662/55142/8481/51259/55755 95 Hepatitis_C_virus_genotype_1a R-HSA-4086400 PCP/CE pathway 90/6120 92/10654 1.2863040827059744e-19 3.02281459435904e-18 1.1373636099715985e-18 5689/5579/5682/5578/1212/81029/5582/143471/5705/5709/5695/5881/5711/5683/5699/5702/57216/1855/163/5696/5691/4920/7314/5879/5718/2535/161/5700/122706/5707/1856/8322/8325/23198/7471/9861/8321/7481/5698/5880/5692/5713/23002/5710/5719/6233/7474/1857/1213/1211/7855/1175/7976/1173/144165/409/5706/160/5714/5688/5687/4919/5708/5704/7311/387/5694/57154/5684/5720/5690/5717/9491/50855/10197/64750/7316/10213/54361/5216/5715/5701/5685/5686/23513/5716/5693/5721/6259/8324 90 Hepatitis_C_virus_genotype_1a R-HSA-9020702 Interleukin-1 signaling 99/6120 103/10654 1.6503552032736224e-19 3.81475546986198e-18 1.435339124158595e-18 8454/5689/4790/5682/8878/143471/5705/5709/9978/5695/4792/177/5711/5683/5699/5702/3654/51135/7334/3551/5696/5691/7314/257397/5718/8945/1326/6283/11213/5700/122706/5707/8767/23198/23118/8517/5970/9861/5698/5692/5713/5710/10454/5719/6233/7850/5608/4791/3557/351/54472/5706/79155/5714/64127/3552/5688/5687/5708/3656/57162/7189/5704/7311/5694/6416/3554/3556/1147/5684/5720/6885/5604/4215/10392/5690/3553/5717/9491/6500/246330/10197/4615/7316/10213/7335/4793/3146/5715/5701/23291/5685/5686/6288/6285/5716/57161/5693/5721 99 Hepatitis_C_virus_genotype_1a R-HSA-373076 Class A/1 (Rhodopsin-like receptors) 269/6120 335/10654 2.238521260292757e-19 5.090830608085141e-18 1.9154748984508484e-18 729230/10316/2532/2149/23620/1880/7852/10161/338442/64805/1237/3354/2841/4987/51289/2150/3060/6349/3576/6360/2798/5737/338557/4985/2920/2921/1236/6010/554/2840/2831/5367/5028/4988/6370/58191/6755/6866/1524/94233/643/5029/2867/185/339403/8843/64106/2847/2833/6347/9290/9170/187/6750/2587/53829/8111/6387/4544/4543/2922/10663/4889/9283/727/1909/117579/3579/6375/23566/2358/1131/6846/5179/27334/27202/5021/6865/6367/2797/8811/56923/2832/2693/27199/2826/6376/165140/27198/7201/5443/6354/3627/3361/6346/553/257313/134/9034/3814/10800/2863/1129/51083/2829/1233/6366/1241/2861/728/183/10022/6373/57121/4922/5731/2865/1132/1814/6357/552/2925/8698/9934/2151/6869/2147/1813/50865/10886/2837/10803/146/3357/351/11251/8477/84432/3352/8484/2828/3062/1907/148/6351/6863/6752/135/1903/84539/6753/3577/594857/5368/6754/6915/8862/10911/301/3061/5032/56670/150/2853/29933/6751/5020/4935/887/4829/186/53637/60675/10563/5540/2864/1901/5733/256933/7200/7252/5729/10850/624/2796/4852/4828/680/5473/4283/1910/6870/128674/11255/885/10874/84634/147/6356/56477/387129/3350/129521/1234/151/57007/3356/84109/9294/4923/1128/283869/4986/6374/5539/2852/1889/1230/3358/4886/2919/1908/5196/3827/5173/2357/6352/57105/1133/140/3269/6348/886/2862/152/1906/6364/7253/5031/8620/5030/5697/56413/3355/3351/6288/6372/5739/719/6363/1268/2359/347148/2846/5660/1815/1325/1232/4295/1902/551/154/9002/1269/59340/5724/4887/718/623 269 Hepatitis_C_virus_genotype_1a R-HSA-453279 Mitotic G1-G1/S phases 135/6120 149/10654 2.3571033009621425e-19 5.275421673581938e-18 1.9849290955470673e-18 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/1031/4998/5711/5928/10926/3717/5683/990/5699/5702/5520/8900/55388/1032/1030/5518/6117/7465/5696/5691/7314/5515/6241/5718/6118/25/23594/7027/5700/5707/7153/898/91768/5934/993/890/983/6714/9861/5519/6502/5698/10000/5692/5713/595/4175/5710/896/5719/6233/7298/23649/1719/1163/1859/4999/4172/26271/1019/8318/1029/4173/5706/286826/891/4331/5714/5111/51053/6119/5688/5687/91750/5427/4067/5708/1874/81620/208/5704/55957/23595/7311/5694/4176/5516/1017/894/5684/5720/4605/902/8317/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1026/5933/5426/4171/5715/5701/5685/5686/1021/3065/5716/1022/5693/5721/7083/132660/1028 135 Hepatitis_C_virus_genotype_1a R-HSA-69618 Mitotic Spindle Checkpoint 106/6120 112/10654 3.3168134154996597e-19 7.194933716699262e-18 2.70716430997867e-18 55839/11130/11065/6249/9735/7321/5526/8697/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/996/5515/79682/10403/25936/3619/64105/332/5528/51433/79902/3796/5519/81565/91687/119504/11243/7324/83540/64682/7514/54820/6396/64946/9793/140735/220134/4928/5903/246184/55055/80776/1783/401541/79172/79980/6232/8881/5501/54821/9183/1062/699/22919/5529/51143/10393/25906/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/79023/55920/1781/4085/55166/79003/5527/701/57551 106 Hepatitis_C_virus_genotype_1a R-HSA-983705 Signaling by the B Cell Receptor (BCR) 106/6120 112/10654 3.3168134154996597e-19 7.194933716699262e-18 2.70716430997867e-18 5295/8454/5689/5777/4893/4790/5579/5682/143471/5705/5530/5709/5695/4792/5711/5683/2534/5699/5702/30011/2885/4794/3845/3265/3551/973/933/5696/5691/7314/6786/5718/8945/4773/5966/5700/122706/5707/5336/23198/10892/8517/10125/5970/25780/9861/5698/5692/5713/5710/2280/5478/5719/6233/7409/3710/118788/801/805/4772/4775/930/5706/6850/8915/5714/5688/5687/4067/29760/5708/695/6654/5704/7311/5293/27071/5694/1147/5684/5720/6885/4690/640/84433/5690/5532/5717/9491/6500/10197/7316/10213/10768/4793/5715/5701/23291/5685/5686/5534/974/5716/808/5693/5721 106 Hepatitis_C_virus_genotype_1a R-HSA-2500257 Resolution of Sister Chromatid Cohesion 117/6120 126/10654 3.873680423555963e-19 8.275589995778648e-18 3.1137718237196258e-18 55839/11130/6249/9735/5526/51807/9212/10274/147841/348995/10381/57122/7278/1780/23122/5048/57405/8655/23279/2491/7846/113457/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/79861/25936/55869/3619/64105/332/5528/983/79902/3796/5519/81565/91687/11243/10376/83540/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/55055/80776/1783/401541/10382/79172/7277/9133/79980/6232/23047/5885/891/5501/54821/9183/1062/699/347733/22919/8243/5529/51143/10383/5347/84790/84643/7280/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23244/23421/79023/55920/10735/112714/1781/4085/55166/79003/9126/5527/701/57551 117 Hepatitis_C_virus_genotype_1a R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 82/6120 83/10654 5.186704532396405e-19 1.075478439805725e-17 4.0465930097953375e-18 8454/5689/4893/4790/5579/5682/143471/5705/5530/5709/5695/4792/5711/5683/5699/5702/4794/3845/3265/3551/5696/5691/7314/5718/8945/4773/5966/5700/122706/5707/23198/10892/8517/10125/5970/25780/9861/5698/5692/5713/5710/2280/5478/5719/6233/801/805/4772/4775/5706/8915/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/84433/5690/5532/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5534/5716/808/5693/5721 82 Hepatitis_C_virus_genotype_1a R-HSA-1236974 ER-Phagosome pathway 82/6120 83/10654 5.186704532396405e-19 1.075478439805725e-17 4.0465930097953375e-18 8773/5689/5682/3107/55176/811/143471/5705/10333/5709/5695/567/3106/5711/5683/929/5699/5702/3133/3551/5696/5691/7314/5718/10952/5700/122706/5707/23198/6892/8517/6810/7096/9861/5698/5692/5713/5710/5719/6233/3135/6890/5706/9554/29927/5714/5688/5687/5708/2923/695/5704/7311/5694/8673/3105/23643/1147/5684/5720/5690/5717/9491/10197/7099/4615/23480/6891/7316/10213/5715/5701/9341/5685/5686/114609/948/5716/3134/7097/5693/5721 82 Hepatitis_C_virus_genotype_1a R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 101/6120 106/10654 5.356322961778057e-19 1.0945529530589942e-17 4.118362734914021e-18 85439/8674/4738/1212/7039/23208/950/554/10980/22848/7037/3482/408/10987/6456/185/30011/2885/163/11037/23149/9185/7314/9856/1839/161/7018/25977/10618/8027/1856/9892/8322/2060/2069/1601/6453/55707/8301/1129/9146/6455/4074/10920/26119/29979/6233/90019/7474/6844/1213/1211/29924/4036/255324/1175/85021/6869/1173/6857/84251/29988/409/160/338/8218/920/22905/2873/7311/1956/8533/8673/50618/51138/9318/685/127833/1080/29978/58513/7316/1950/64708/3267/3949/867/9341/915/917/6572/115548/1861/143425/3575/6845/551/154/10254/6457/50813 101 Hepatitis_C_virus_genotype_1a R-HSA-2262752 Cellular responses to stress 366/6120 479/10654 5.569244562715041e-19 1.1218049762040296e-17 4.2209011422682415e-18 1912/23165/5689/3725/6782/9134/2077/11065/573/4790/5682/64344/7531/1915/7321/51807/817/6045/8697/9530/23677/27327/80012/7295/5925/3091/348995/143471/472/10381/57122/5705/79813/3576/7278/3313/1780/7001/23511/10312/5709/9978/2114/1869/5695/3305/8655/84516/1911/832/26277/23279/4194/1031/91582/5711/5928/1432/1387/4683/7846/259217/23225/113457/5683/3309/23512/57332/5699/126374/7428/5702/192669/9531/8900/51529/4001/29945/8091/8131/2056/51434/2475/1032/3306/27000/1030/6196/9972/23411/8021/4343/6117/10587/6197/29882/3312/4217/54386/3569/64121/55746/5696/5691/7296/7314/51164/996/51182/5718/818/3303/7014/6118/5601/79861/2876/5606/7027/526/5700/122706/5707/2146/9550/2936/9114/5594/3308/23198/898/10049/10013/27244/100532731/3337/10762/847/7323/890/5970/9261/6667/51433/9861/79902/5598/9883/2932/84733/9973/529/5698/5692/5713/2877/119504/10376/6195/5710/3301/10540/7157/7324/5719/64682/6233/2353/538/8726/6396/1535/129401/5600/523/201163/26523/528/405/5608/3297/57521/140735/768/6015/28956/84617/4928/4688/1019/5903/83667/55706/7175/653361/5241/11258/9448/246184/112399/1029/1783/389541/25828/8535/84962/10382/93661/5931/10294/55860/830/7013/7277/1051/1410/50488/5706/10671/8881/527/6774/1639/5714/4927/7867/64223/6119/3552/10370/10524/5688/5687/57805/3281/3310/2908/5708/347733/5602/7266/25824/6009/51143/816/6648/8086/10393/5704/3326/55004/51343/7311/367/25906/2034/79400/57634/10383/84790/55662/648/5694/3304/23466/3456/2113/6416/10641/257202/7280/10728/829/2880/23523/5595/1778/1017/815/25913/81929/5684/5720/9631/3159/7290/116835/10111/475/2878/7422/5690/57690/5717/1027/9491/545/79023/23636/10197/192670/10808/112714/3490/8550/29855/4306/1781/7316/10213/10935/53371/1026/9532/54205/2289/9588/9688/10121/7415/6647/8994/7322/5715/2882/5701/245972/144577/5685/8649/3320/65057/5686/2033/1021/6767/25842/493869/8453/50507/23135/10963/22824/57600/23112/5609/10542/5716/9529/5599/54583/5052/1536/96459/5693/5721/55466/2288/5034/8480/10919/51382/2950/4193/9296/23043 366 Hepatitis_C_virus_genotype_1a R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 92/6120 95/10654 6.03294251794038e-19 1.1814512430966578e-17 4.445326065850807e-18 8454/3725/9252/4790/1848/10333/4792/59307/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/11213/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/57161 92 Hepatitis_C_virus_genotype_1a R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 92/6120 95/10654 6.03294251794038e-19 1.1814512430966578e-17 4.445326065850807e-18 8454/3725/9252/4790/1848/10333/4792/59307/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/11213/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/57161 92 Hepatitis_C_virus_genotype_1a R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 116/6120 125/10654 6.313922528904187e-19 1.2195384610623157e-17 4.588632955396843e-18 56955/4240/3270/9210/10272/2153/1511/7857/29106/91851/6696/51156/1435/265/11098/10130/2200/80341/375056/1114/720/10117/3956/3569/54972/2519/8720/7018/5340/10618/11167/813/5179/8074/4312/51246/348/4924/4313/3484/102/8614/336/6694/4148/174/57104/721/2335/7466/116519/2266/51280/7076/2243/60676/84141/3488/2147/8542/4221/351/4052/7184/56975/334/3912/338/64856/335/5611/197/3053/3895/5624/1000/54757/3481/8404/255738/3913/354/652/57719/147111/2719/3487/3371/54587/401138/3486/7425/6383/3827/3490/5589/2621/3915/5768/1471/1462/10232/462/3698/5265/1758/3483/258/11320/5954/3479/213/10970/5034/1356/718 116 Hepatitis_C_virus_genotype_1a R-HSA-68886 M Phase 309/6120 395/10654 7.803790845345107e-19 1.4869385259373785e-17 5.594751900503463e-18 114791/10844/23165/5689/55839/11130/11065/440145/6249/5579/5682/9735/7531/1459/11190/7321/91754/203068/5526/54801/51807/8697/5578/9212/10274/5861/5925/1460/147841/348995/79441/143471/10381/57122/5705/5116/7278/1780/23122/23511/5048/5709/5695/57405/8655/1457/23279/9702/5711/2491/10112/7846/23225/7840/113457/5683/1060/5699/11064/5702/5520/51529/4001/29945/11004/51434/9184/9972/5518/55844/55835/29922/8021/29882/23332/84930/25909/10726/81930/55746/5696/93323/5691/7314/996/5515/5718/79682/10403/79861/64151/25936/55869/5700/122706/5707/1454/2801/5594/3619/23198/64105/23310/332/10762/10051/5528/983/8548/51433/9861/79902/3796/8615/79959/5519/9883/81565/7444/5698/5692/5713/80097/91687/119504/11243/10376/23397/5710/10540/85378/7324/2010/83540/5719/64682/6233/23175/7514/54930/54820/113130/9493/6396/129401/1453/27229/64946/9793/140735/220134/84617/4928/26271/5903/55706/7175/11258/22981/246184/55055/8636/80776/1783/401541/7532/55125/10382/79172/121441/7277/5706/9133/79980/6232/23047/8881/9814/653784/5885/23354/891/5501/9738/1639/5714/55722/4957/4927/5566/54821/81876/9183/5688/1062/699/5687/7283/5708/347733/22919/8243/10426/5529/22994/51143/1069/8086/10393/79648/5577/5704/7311/25906/10383/5347/54892/84790/84643/80184/5694/22897/6418/5108/7112/10592/7280/10806/29781/5595/1778/5516/4000/115106/4926/5905/22995/55559/81929/5684/5720/54908/55143/9631/5525/10142/23383/1058/991/79019/5862/348235/80152/5690/1063/8379/95681/5717/9491/140609/23244/23421/79023/55920/23636/10735/10197/7443/112714/23141/1781/7316/10213/80321/53371/26003/4085/9688/55166/10121/5715/84131/5701/5685/3320/8815/5686/79003/9126/9918/10733/4751/9232/23592/5527/9700/27175/80254/5716/701/57551/9662/55142/64689/8481/5693/5721/55755/8480 309 Hepatitis_C_virus_genotype_1a R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 91/6120 94/10654 1.0238123130941118e-18 1.9247671486169303e-17 7.242124993676244e-18 8454/3725/9252/4790/7321/1848/4792/177/1432/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/23098/11035/8945/1326/5601/6283/5606/8737/8767/1849/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5608/4791/1846/3665/351/330/7098/79155/7867/64127/5602/3656/7189/7311/9641/6416/5595/5516/1147/1845/6885/5604/10392/6500/7316/7335/4205/4793/3146/7322/329/466/23291/6288/2002/6285/5609/1385/5599/148022 91 Hepatitis_C_virus_genotype_1a R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 86/6120 88/10654 1.107936524776582e-18 2.055513815703922e-17 7.734072139714646e-18 8454/7531/11190/203068/54801/79441/5116/5048/8655/6790/9702/7846/7840/11064/5518/55835/23332/93323/7314/8945/4659/1454/983/79959/10540/6233/54930/54820/1453/9793/4218/5500/11258/22981/8636/7532/84962/55125/10382/121441/7277/9133/9814/23354/891/9738/1639/55722/4957/5566/7283/22919/22994/79866/1069/5577/7311/10133/10383/5347/80184/22897/5108/4660/10806/1778/115106/22995/55559/10142/95681/6500/1781/7316/80321/10121/84131/23291/3320/10733/4751/80254/9662/55142/8481/55755 86 Hepatitis_C_virus_genotype_1a R-HSA-166166 MyD88-independent TLR4 cascade 95/6120 99/10654 1.3271377794631859e-18 2.3990567551834514e-17 9.026686111328552e-18 8454/3725/9252/4790/7321/1848/4792/177/1432/929/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/23098/11035/8945/1326/5601/6283/5606/8737/8767/1849/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/1846/3665/351/330/79155/7867/64127/5602/3656/7189/7311/9641/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/7316/7335/4205/4793/3146/7322/329/466/23291/6288/2002/6285/5609/1385/5599/353376/148022 95 Hepatitis_C_virus_genotype_1a R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 95/6120 99/10654 1.3271377794631859e-18 2.3990567551834514e-17 9.026686111328552e-18 8454/3725/9252/4790/7321/1848/4792/177/1432/929/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/23098/11035/8945/1326/5601/6283/5606/8737/8767/1849/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/1846/3665/351/330/79155/7867/64127/5602/3656/7189/7311/9641/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/7316/7335/4205/4793/3146/7322/329/466/23291/6288/2002/6285/5609/1385/5599/353376/148022 95 Hepatitis_C_virus_genotype_1a R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 79/6120 80/10654 2.6831683866267612e-18 4.7889461077768774e-17 1.8018878972150404e-17 8454/5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 79 Hepatitis_C_virus_genotype_1a R-HSA-877300 Interferon gamma signaling 89/6120 92/10654 2.9448866957370243e-18 5.1903628012365056e-17 1.9529248613835005e-17 80263/5777/960/5770/3107/817/9021/3383/55223/3662/3115/4684/567/6672/3113/3106/3459/3717/3117/11074/5371/3133/117854/3127/4938/4261/818/115362/7412/85363/9830/163351/3126/2634/115361/10475/10437/10612/3458/3661/5580/81603/10107/4940/5781/3660/8554/3135/3665/3120/10379/2633/3123/23650/2209/8638/7706/23087/3122/3394/3663/6772/8651/3659/2635/5771/816/10346/3716/3125/7726/79097/3105/3460/815/6737/23321/4281/3119/4502/51127/3664/4939/388646/7341/55128/3134/80128/5724 89 Hepatitis_C_virus_genotype_1a R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 93/6120 97/10654 3.752749078095501e-18 6.532563210018094e-17 2.457940916647346e-17 8454/3725/9252/4790/1848/4792/177/1432/929/3654/51135/6196/5518/1386/6197/64145/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/6283/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/30849/5608/4791/1846/3665/351/8411/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/5289/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/353376/57161/148022 93 Hepatitis_C_virus_genotype_1a R-HSA-8878166 Transcriptional regulation by RUNX2 112/6120 121/10654 4.426370029210344e-18 7.611197245349494e-17 2.8637875413633036e-17 8454/8493/5689/7291/5682/5925/143471/5705/5709/9978/5695/9759/10413/4089/3549/5711/5683/2101/1749/5699/5702/5696/5691/7314/5718/25/6662/5700/122706/5707/5594/3280/23198/100526737/10013/2737/865/11059/983/6714/2099/9861/2932/6502/5698/10000/5692/5713/595/5710/5719/6233/7525/10432/133522/4091/117581/1019/3958/5706/3678/1277/891/579/5714/6772/2736/5688/5687/4322/2908/5708/4488/208/5704/7311/367/860/1750/5694/5595/57154/5684/8841/5720/23462/10273/207/5690/5717/9491/6500/4086/59269/10197/7316/10213/4094/1026/5715/5701/5685/5686/55294/23314/861/5716/25937/581/5693/5721/10891 112 Hepatitis_C_virus_genotype_1a R-HSA-8878159 Transcriptional regulation by RUNX3 92/6120 96/10654 6.305866043628498e-18 1.071237484520022e-16 4.030635999985749e-17 5689/6046/5682/182/5705/6097/6696/5709/5695/9759/10413/4609/4089/22938/5711/1387/7005/4088/5683/7003/5699/5702/9794/6932/7040/3845/5696/5691/7314/5718/8463/51176/2648/5700/5707/55534/3280/84441/463/865/83439/6714/9861/8850/5698/5692/5713/595/5710/7157/5719/6233/1029/864/5706/10046/5714/6934/5688/5687/5708/5704/7311/5694/4851/3676/57154/5684/5720/2309/1499/10018/5690/5717/9491/10197/64750/7316/10213/1026/5715/5701/5685/5686/2033/861/5716/25937/3516/5693/5721/4193 92 Hepatitis_C_virus_genotype_1a R-HSA-2219528 PI3K/AKT Signaling in Cancer 96/6120 101/10654 6.936804684963687e-18 1.1373133262556744e-16 4.2792528289127283e-17 5295/2308/2250/5291/7039/3082/941/2064/145957/2534/9965/2264/9542/2885/2475/8660/2252/2253/5879/1839/5290/3667/8823/2065/3815/2069/8074/7249/2260/2249/6714/2099/2248/2932/2247/5880/10000/7409/2246/2251/5154/3932/2931/118788/255324/5781/940/253260/5170/572/4303/930/6199/2263/4233/64223/8503/5159/29851/3084/208/10718/79109/5293/1956/2549/1147/8822/685/2309/842/207/1027/8817/2100/2254/152831/1950/1026/50852/26281/10818/2261/2255/3164/391/5728/2066/27006/942/1385/5155/4254/5296/5156/4193 96 Hepatitis_C_virus_genotype_1a R-HSA-5607764 CLEC7A (Dectin-1) signaling 96/6120 101/10654 6.936804684963687e-18 1.1373133262556744e-16 4.2792528289127283e-17 8454/5689/4790/5682/7321/9039/29108/143471/5705/5530/5709/5695/4792/5711/5683/5699/5702/7334/3551/5696/5691/7314/257397/5718/8945/4773/5700/122706/5707/5336/23198/23118/10892/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/3710/801/4791/805/5170/4772/4775/5706/64581/6850/8915/5714/5688/5687/5708/7189/5704/7311/5971/5694/997/1147/5684/5720/6885/84433/5690/3553/5532/5717/9491/6500/10197/7316/10213/7335/10768/7322/5715/5701/23291/5685/5686/5534/5716/808/5693/5721 96 Hepatitis_C_virus_genotype_1a R-HSA-72689 Formation of a pool of free 40S subunits 96/6120 101/10654 6.936804684963687e-18 1.1373133262556744e-16 4.2792528289127283e-17 6158/6138/6206/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/6202/6169/6175/6218/6173/6167/6192/6156/6143/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/8663/23521/6207/6233/51386/6188/200916/6122/6230/8669/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/8664/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6164/8661/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 96 Hepatitis_C_virus_genotype_1a R-HSA-69052 Switching of origins to a post-replicative state 87/6120 90/10654 8.456357354556845e-18 1.370513088497144e-16 5.15668978426697e-17 8454/5689/9134/11065/5682/7321/8697/143471/5705/5709/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/29882/5696/5691/7314/996/5718/23594/5700/122706/5707/23198/898/890/51433/9861/6502/5698/5692/5713/119504/4175/5710/7324/5719/64682/6233/4999/4172/246184/4173/5706/8881/5714/5688/5687/5708/81620/10393/5704/51343/23595/7311/25906/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 87 Hepatitis_C_virus_genotype_1a R-HSA-9007101 Rab regulation of trafficking 114/6120 124/10654 9.034088149762352e-18 1.447507305814195e-16 5.446388071148596e-17 5869/163486/116442/126003/7531/22878/1122/54453/10981/83874/5861/163259/5866/23011/9610/60684/3257/414918/51762/51552/9230/83452/126432/201475/5874/79961/221960/2665/79090/22898/58485/5868/128637/81846/51622/7249/23637/26000/84079/51209/5872/9827/80006/5870/8408/9909/10000/64786/51112/117177/83696/1121/23682/27095/6399/7109/4218/7879/2664/201627/26088/27342/414060/23258/9363/5864/10260/382/57679/81876/9135/259173/6305/51693/8567/208/5867/79890/22879/10133/11345/54734/57589/84315/7248/22931/51399/10890/23062/207/11337/51256/122553/79958/57706/8766/22930/55667/26130/27147/25782/9367/51560/11021/5873/79735/81631/5878/11031/23163/338382/57465/89781/160518 114 Hepatitis_C_virus_genotype_1a R-HSA-72613 Eukaryotic Translation Initiation 110/6120 119/10654 1.167044586847252e-17 1.8283698527273614e-16 6.879420722468012e-17 6158/6138/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/6192/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/1978/200916/6122/1968/6230/8669/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/8891/51121/6159/6217/6152/51065/6141/10480/6164/8661/9669/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 110 Hepatitis_C_virus_genotype_1a R-HSA-72737 Cap-dependent Translation Initiation 110/6120 119/10654 1.167044586847252e-17 1.8283698527273614e-16 6.879420722468012e-17 6158/6138/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/6192/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/1978/200916/6122/1968/6230/8669/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/8891/51121/6159/6217/6152/51065/6141/10480/6164/8661/9669/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 110 Hepatitis_C_virus_genotype_1a R-HSA-5663220 RHO GTPases Activate Formins 126/6120 140/10654 1.5059074750433168e-17 2.333329164627557e-16 8.77937961158857e-17 55839/11130/71/6249/9735/5526/51807/9212/388/147841/348995/10381/57122/7278/1780/23122/3688/5048/57405/8655/23279/2491/7846/113457/1060/11004/1855/9184/5518/23332/25909/10726/81930/55746/5879/5515/79682/10403/79861/25936/1856/389/3619/64105/332/5528/6714/79902/3796/5519/81565/91687/11243/10376/23002/83540/1857/7514/54820/29984/1729/6396/64946/9793/140735/220134/84617/4928/114793/5903/55055/80776/1783/401541/10382/79172/7277/79980/6232/5501/54821/9183/1062/699/752/347733/22919/5529/51143/998/10383/5347/387/60/84790/84643/7280/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/6722/8379/23421/79023/55920/112714/1781/4085/5216/81624/55166/79003/5527/701/23380/57551 126 Hepatitis_C_virus_genotype_1a R-HSA-162587 HIV Life Cycle 135/6120 152/10654 1.6383973682419926e-17 2.5110220535013145e-16 9.447966517093412e-17 6884/23165/6875/51652/2237/7852/27243/6874/348995/57122/55048/3981/5431/23511/5435/5433/2960/51271/23279/23327/29082/23225/2965/27183/5439/6873/3836/9972/6881/2967/51616/8021/11198/904/51497/55746/92421/7314/137492/25978/51160/2959/7518/404672/10015/91782/5438/3978/10762/79720/51534/4836/9397/79902/9883/89853/83860/51510/2068/5902/5478/6233/7514/1025/6396/129401/6883/6829/2957/25920/4928/2963/5434/5903/55706/7175/79643/5436/6878/920/4331/4927/8148/2966/2962/54457/8812/128866/2071/5901/8086/7311/93343/6880/6908/7251/1104/2547/6882/2961/5432/22916/155382/1234/6877/5905/6917/81929/5440/902/9631/3159/5430/5045/7520/6749/79023/5441/23636/4686/7316/6872/53371/9688/6879/9525/2958/5437/8815/6827/2968/138474/1022/8178/8480 135 Hepatitis_C_virus_genotype_1a R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 90/6120 94/10654 1.7777586616034282e-17 2.695311519205198e-16 1.0141373689282714e-16 114791/10844/440145/7531/11190/203068/54801/51807/79441/10381/5116/7278/5048/8655/9702/7846/7840/113457/11064/5518/55835/29922/23332/93323/79861/1454/983/79959/80097/10376/10540/85378/54930/54820/1453/27229/9793/84617/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/9738/1639/55722/4957/5566/7283/347733/22919/10426/22994/1069/5577/10383/5347/84790/80184/22897/5108/7280/10806/1778/115106/4926/22995/55559/10142/95681/112714/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 90 Hepatitis_C_virus_genotype_1a R-HSA-1236975 Antigen processing-Cross presentation 94/6120 99/10654 1.9247939783128504e-17 2.8871909674692755e-16 1.0863338914554052e-16 8773/5689/5682/3107/55176/811/143471/5705/10333/5709/5695/567/3693/3106/5711/5683/929/5699/5702/3133/3551/5696/5691/7314/5718/10952/5700/122706/5707/23198/6892/8517/6810/7096/9861/5698/5692/5713/5710/5719/6233/3685/1535/1514/3135/4688/653361/6890/2209/5706/9554/29927/5714/5688/5687/5708/2923/695/9902/5704/4012/7311/5694/8673/3105/23643/1147/5684/5720/5690/5717/9491/10197/7099/4615/23480/6891/7316/10213/5715/5701/9341/5685/5686/114609/948/1520/5716/3134/7097/1536/5693/5721/4360 94 Hepatitis_C_virus_genotype_1a R-HSA-69206 G1/S Transition 119/6120 131/10654 1.9956907912685237e-17 2.96202527967223e-16 1.1144910346807049e-16 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/4998/5711/5928/10926/5683/990/5699/5702/8900/55388/5518/6117/7465/5696/5691/7314/5515/6241/5718/6118/23594/7027/5700/5707/898/91768/5934/993/890/983/9861/5519/6502/5698/10000/5692/5713/595/4175/5710/5719/6233/7298/23649/1719/1163/4999/4172/26271/1019/8318/4173/5706/286826/891/4331/5714/5111/51053/6119/5688/5687/91750/5427/5708/1874/81620/208/5704/55957/23595/7311/5694/4176/5516/1017/5684/5720/902/8317/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1026/5933/5426/4171/5715/5701/5685/5686/3065/5716/1022/5693/5721/7083/132660 119 Hepatitis_C_virus_genotype_1a R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 75/6120 76/10654 2.3931206079288232e-17 3.514895892895459e-16 1.3225140201711918e-16 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 75 Hepatitis_C_virus_genotype_1a R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 85/6120 88/10654 2.4240265652874448e-17 3.523585007273502e-16 1.3257833845956292e-16 5393/5689/5682/23404/5578/26986/143471/5705/5709/5695/5711/1432/5683/5699/5702/11340/8021/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/7534/9261/8741/9861/5698/5692/5713/1981/5710/5719/6233/5580/7514/5600/8570/23016/118460/1994/5073/3842/3315/5706/8125/7538/5714/5688/5687/5708/5704/7311/51010/5694/56915/3304/6418/167227/7529/22894/5684/5720/207/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/51013/5716/54464/5693/54512/5721 85 Hepatitis_C_virus_genotype_1a R-HSA-8953897 Cellular responses to external stimuli 371/6120 493/10654 2.550375448713827e-17 3.6694177374352003e-16 1.3806543782510943e-16 1912/23165/5689/3725/6782/9134/2077/11065/573/4790/5682/64344/7531/1915/7321/51807/817/6045/8697/9530/23677/27327/80012/7295/5925/3091/348995/143471/472/10381/57122/5705/79813/3576/7278/3313/1780/7001/23511/10312/5709/9978/2114/1869/5695/3305/8655/84516/1911/832/26277/23279/4194/1031/91582/5711/5928/1432/1387/4683/7846/259217/23225/113457/5683/3309/23512/57332/5699/126374/7428/5702/192669/9531/8900/51529/4001/29945/8091/8131/2056/51434/2475/1032/3306/27000/1030/6196/9972/23411/8021/4343/6117/10587/6197/29882/3312/4217/54386/3569/64121/55746/5696/5691/7296/7314/51164/996/51182/6620/5718/818/3303/7014/6118/5601/79861/2876/5606/7027/526/5700/122706/5707/2146/9550/2936/9114/5594/3308/23198/898/10049/10013/27244/100532731/3337/10762/847/7323/1465/890/5970/9261/6667/51433/9861/79902/5598/9883/2932/84733/9973/529/5698/5692/5713/2877/119504/10376/6195/5710/3301/10540/7157/7324/5719/64682/6233/2353/538/8726/6396/1535/129401/5600/523/201163/26523/528/405/5608/3297/57521/140735/768/6015/28956/84617/4928/4688/1019/5903/83667/55706/7175/653361/5241/11258/9448/246184/112399/1029/1783/389541/25828/8535/84962/10382/93661/5931/10294/55860/830/7013/7277/1051/1410/50488/5706/10671/8881/527/6774/1639/5714/4927/7867/64223/6119/3552/10370/10524/5688/5687/57805/3281/3310/2908/5708/347733/5602/7266/25824/6009/51143/816/6648/8086/10393/5704/3326/55004/51343/7311/367/25906/2034/79400/57634/10383/84790/55662/648/5694/3304/23466/3456/2113/6416/10641/257202/7280/10728/829/2880/23523/5595/1778/1017/815/25913/81929/5684/5720/9631/3159/7290/116835/10111/475/4502/2878/7422/5690/57690/5717/1027/9491/545/79023/23636/10197/192670/10808/112714/3490/8550/29855/4306/1781/7316/10213/4501/10935/53371/1026/9532/54205/2289/9588/9688/10121/7415/6647/8994/7322/5715/2882/5701/245972/144577/5685/8649/3320/65057/5686/2033/1021/6767/25842/493869/8453/50507/23135/10963/22824/57600/23112/5609/10542/5716/9529/4520/5599/54583/5052/1536/96459/5693/5721/55466/2288/5034/8480/10919/51382/2950/4193/9296/23043 371 Hepatitis_C_virus_genotype_1a R-HSA-195253 Degradation of beta-catenin by the destruction complex 80/6120 82/10654 2.773277162389792e-17 3.8336478421270657e-16 1.442447564338963e-16 8454/5689/5682/5526/1452/143471/5705/5709/9978/5695/5711/5683/324/5699/8312/5702/6932/5518/5696/5691/7314/5515/5718/51176/8945/5700/122706/5707/23198/5528/7091/83439/9861/5519/2932/5698/5692/5713/5710/5719/6233/7089/7090/10023/5706/23401/5714/6934/5688/5687/5708/5529/7088/5704/7311/5694/5516/5684/5720/1487/1499/5525/139285/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/3065/5527/1488/5716/5693/5721 80 Hepatitis_C_virus_genotype_1a R-HSA-2871837 FCERI mediated NF-kB activation 80/6120 82/10654 2.773277162389792e-17 3.8336478421270657e-16 1.442447564338963e-16 8454/5689/4790/5682/7321/143471/5705/5709/5695/4792/5711/5683/5699/5702/7334/3551/5696/5691/7314/257397/5718/8945/5700/122706/5707/23198/23118/10892/8517/10125/5970/9861/5588/5698/5692/5713/5710/10454/5719/6233/115727/5170/2205/5706/2206/8915/5714/5688/5687/4067/5708/7189/5704/7311/5694/997/1147/5684/5720/6885/84433/5690/5717/9491/6500/10197/7316/10213/7335/7322/5715/5701/23291/5685/5686/5716/10235/5693/5721/2207 80 Hepatitis_C_virus_genotype_1a R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 80/6120 82/10654 2.773277162389792e-17 3.8336478421270657e-16 1.442447564338963e-16 114791/10844/440145/7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/1454/983/79959/80097/10540/85378/54930/54820/1453/27229/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/728642/9738/1639/55722/4957/5566/7283/22919/984/10426/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 80 Hepatitis_C_virus_genotype_1a R-HSA-380287 Centrosome maturation 80/6120 82/10654 2.773277162389792e-17 3.8336478421270657e-16 1.442447564338963e-16 114791/10844/440145/7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/1454/983/79959/80097/10540/85378/54930/54820/1453/27229/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/728642/9738/1639/55722/4957/5566/7283/22919/984/10426/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 80 Hepatitis_C_virus_genotype_1a R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 89/6120 93/10654 2.982617561420438e-17 4.043741116925786e-16 1.5214972175667012e-16 8454/3725/9252/4790/1848/4792/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/6283/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/1846/3665/351/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/353376/57161/148022 89 Hepatitis_C_virus_genotype_1a R-HSA-975155 MyD88 dependent cascade initiated on endosome 89/6120 93/10654 2.982617561420438e-17 4.043741116925786e-16 1.5214972175667012e-16 8454/3725/9252/4790/1848/4792/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/6283/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/1846/3665/351/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/353376/57161/148022 89 Hepatitis_C_virus_genotype_1a R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 93/6120 98/10654 3.2034426441335456e-17 4.261183139838018e-16 1.6033119092783585e-16 8454/3725/9252/4790/1848/10333/4792/59307/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/11213/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/653509/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/57161 93 Hepatitis_C_virus_genotype_1a R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 93/6120 98/10654 3.2034426441335456e-17 4.261183139838018e-16 1.6033119092783585e-16 8454/3725/9252/4790/1848/10333/4792/59307/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/11213/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/653509/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/57161 93 Hepatitis_C_virus_genotype_1a R-HSA-416476 G alpha (q) signalling events 182/6120 217/10654 3.5204669295471877e-17 4.639119972580873e-16 1.7455143457863087e-16 5295/2788/10316/2149/23620/4893/10161/5331/5578/2150/3060/5583/2769/2798/5737/338557/2911/2840/5367/5028/6866/94233/5029/2782/2867/2776/185/2885/6196/64106/2847/9170/6197/3845/3265/8111/2787/2922/1839/5290/1909/6375/23566/2358/1131/6846/5594/27334/10681/5021/6865/2797/56923/2693/10125/7201/2792/553/257313/5598/3814/10800/5588/2863/2785/6195/2783/2784/2829/222545/8525/1241/5332/183/5580/57121/4922/5731/2865/3710/552/2925/2151/6869/2791/2147/10886/2520/2837/146/3357/351/8477/84432/2828/3062/1907/148/6863/84539/594857/6915/10911/301/3061/5032/2642/29933/5020/4935/887/4829/60675/8503/2864/10287/23236/7200/624/2641/2796/4828/695/2786/680/6654/1910/6870/128674/885/1956/10874/84634/147/387129/129521/5595/3356/84109/54331/4923/1128/59345/26090/846/3358/1908/51764/94235/5330/3827/55970/57105/1133/4314/3269/2767/886/2862/1906/5031/8620/2793/56413/6288/2869/1385/10235/5296/5581/347148/2846/9630/4295/1902/551/9002/2915/5724/2790/6003/623 182 Hepatitis_C_virus_genotype_1a R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 74/6120 75/10654 4.1332322351991605e-17 5.39616430706557e-16 2.0303596944837982e-16 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 74 Hepatitis_C_virus_genotype_1a R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 88/6120 92/10654 5.0013880985666296e-17 6.469685521999035e-16 2.434282570427409e-16 8454/3725/9252/4790/1848/4792/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/6283/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/1846/351/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/353376/57161/148022 88 Hepatitis_C_virus_genotype_1a R-HSA-162909 Host Interactions of HIV factors 117/6120 129/10654 5.071769967872689e-17 6.501086958818628e-16 2.446097668715632e-16 23165/5689/162/5682/348995/143471/57122/5705/23511/5709/9978/5695/292/567/23279/5711/23225/5683/2534/5699/5702/3836/163/9972/8021/904/55690/5062/55746/5696/5691/7314/5879/5718/8945/161/5700/122706/5707/23198/10762/926/9861/79902/9883/5698/5692/5713/5710/5902/5478/5719/6233/7514/1025/3932/6396/129401/1175/8907/940/60489/1173/4928/5903/55706/7175/4869/5706/160/293/920/5714/4927/5688/5687/5708/5901/8086/5704/7311/5694/1104/5905/3837/81929/164/5684/8065/5720/9631/3159/5690/5717/9491/6500/79023/23636/10197/919/7316/10213/53371/3055/9688/5715/5701/5685/8815/5686/5716/9844/375/5693/5721/8480/291 117 Hepatitis_C_virus_genotype_1a R-HSA-446652 Interleukin-1 family signaling 125/6120 140/10654 9.667580092840104e-17 1.2280439577391483e-15 4.620635720048756e-16 8454/834/5689/5777/4790/5682/1511/26469/5783/27178/8878/143471/5705/5709/9978/5695/4792/59307/3606/177/5711/4088/5683/84867/5699/5702/3654/51135/7334/3551/5696/5691/7314/3596/257397/5718/8945/1326/6283/90865/11213/5700/122706/5707/8767/29110/23198/23118/8517/3565/5970/8809/9861/5698/5692/5713/5710/10454/5719/6233/7850/5781/5608/4791/3557/56300/351/5782/54472/5706/79155/6774/5714/64127/3552/5688/5687/5708/3656/57162/5771/7189/5704/84639/7311/5694/6416/3554/3556/1147/5778/5684/5720/6885/5604/4215/10392/5690/3553/5717/9491/6500/25930/246330/10197/4615/7316/10213/7335/4793/3146/5715/5701/23291/5685/5686/6288/6285/5716/9173/5599/5784/57161/5693/5721 125 Hepatitis_C_virus_genotype_1a R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 82/6120 85/10654 1.1724060451039678e-16 1.4374717596492126e-15 5.408628345376658e-16 8454/3725/9252/4790/1848/4792/177/1432/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/81793/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/246330/4615/7100/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 82 Hepatitis_C_virus_genotype_1a R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 82/6120 85/10654 1.1724060451039678e-16 1.4374717596492126e-15 5.408628345376658e-16 8454/3725/9252/4790/1848/4792/177/1432/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/81793/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/246330/4615/7100/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 82 Hepatitis_C_virus_genotype_1a R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 82/6120 85/10654 1.1724060451039678e-16 1.4374717596492126e-15 5.408628345376658e-16 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/91768/5934/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/1163/1019/5706/286826/4331/5714/5688/5687/91750/5708/1874/208/5704/55957/51343/7311/5694/1017/5684/994/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1026/5715/5701/5685/5686/5716/1022/5693/5721/132660 82 Hepatitis_C_virus_genotype_1a R-HSA-975871 MyD88 cascade initiated on plasma membrane 82/6120 85/10654 1.1724060451039678e-16 1.4374717596492126e-15 5.408628345376658e-16 8454/3725/9252/4790/1848/4792/177/1432/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/81793/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/246330/4615/7100/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 82 Hepatitis_C_virus_genotype_1a R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72/6120 73/10654 1.2320332230981382e-16 1.4975576246279094e-15 5.634707299831776e-16 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/5716/701/5693/5721 72 Hepatitis_C_virus_genotype_1a R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 90/6120 95/10654 1.47143377966577e-16 1.7732663498536203e-15 6.672088393626164e-16 6158/6138/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/6173/6167/6192/6156/6143/6139/3921/6208/6170/6203/6147/6222/2935/6134/6155/6231/6142/23521/1981/6207/6233/6188/5976/200916/6122/6230/6194/2107/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/23708/9045/6187/6168/22916/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/4686/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 90 Hepatitis_C_virus_genotype_1a R-HSA-8873719 RAB geranylgeranylation 65/6120 65/10654 1.9379944094073412e-16 2.315739082427416e-15 8.713195203758253e-16 5869/116442/1122/10981/5861/23011/51762/376267/51552/9230/83452/27314/10966/201475/5874/339122/8073/5868/55647/51209/326624/5872/9545/57111/347517/5870/1121/23682/4218/401258/142684/7879/5875/51715/25837/115827/401409/9363/5864/57799/53917/57403/81876/8934/5867/54734/115273/83871/53916/22931/9609/64284/10890/84932/5862/8766/9367/5876/51560/11021/5873/5878/11031/5865/338382 65 Hepatitis_C_virus_genotype_1a R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 71/6120 72/10654 2.1263059902460421e-16 2.4777615258239e-15 9.32282052269687e-16 5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 71 Hepatitis_C_virus_genotype_1a R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 71/6120 72/10654 2.1263059902460421e-16 2.4777615258239e-15 9.32282052269687e-16 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 71 Hepatitis_C_virus_genotype_1a R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 71/6120 72/10654 2.1263059902460421e-16 2.4777615258239e-15 9.32282052269687e-16 5689/9134/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/990/5699/5702/8900/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/898/890/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/1017/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 71 Hepatitis_C_virus_genotype_1a R-HSA-4420097 VEGFA-VEGFR2 Pathway 93/6120 99/10654 2.3022496964354784e-16 2.6607967803065777e-15 1.0011508602273349e-15 5295/4893/857/5335/71/5579/5291/5578/1432/2534/9475/3690/5603/2475/6093/8440/9564/3845/3265/3071/8877/5062/5829/5879/26999/5290/5567/10006/5921/1500/9261/6714/10810/10000/3728/7410/5580/7409/23191/3685/3791/3710/1535/5600/6300/801/10787/253260/805/5170/4688/5590/653361/6461/5747/5568/3315/10451/1793/10152/7867/64223/5566/1003/10163/55845/5063/998/208/79109/2185/387/60/5058/63916/25759/558/1495/1499/4690/207/7422/10458/9047/10768/8936/3320/4846/1398/9844/5296/808/1536 93 Hepatitis_C_virus_genotype_1a R-HSA-69202 Cyclin E associated events during G1/S transition 80/6120 83/10654 3.345020263690106e-16 3.834535424230122e-15 1.4427815258021511e-15 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/91768/5934/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/1163/1019/5706/286826/4331/5714/5688/5687/91750/5708/1874/208/5704/55957/7311/5694/1017/5684/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1026/5715/5701/5685/5686/5716/1022/5693/5721/132660 80 Hepatitis_C_virus_genotype_1a R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 103/6120 112/10654 3.3917918580874037e-16 3.8567955805671286e-15 1.4511571277385835e-15 6158/6138/6206/6234/6191/6128/6132/6129/6176/55176/6224/6146/6154/6202/6169/6175/6218/6728/6173/6167/6192/6156/6143/6139/6745/3921/6208/6170/6203/10952/6147/6222/6727/6184/58477/6134/6747/6731/6155/6729/6231/6142/23521/6185/6207/6726/6233/6188/200916/6122/6230/6194/6166/1650/6136/6125/6232/6160/6748/29927/60559/6193/6210/6229/6205/28972/140801/6235/6181/23471/7311/6223/25873/6730/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/23480/6164/6209/11224/6165/6130/6204/6228/6124/6189/9789/6135/6201/6161/6133 103 Hepatitis_C_virus_genotype_1a R-HSA-6802957 Oncogenic MAPK signaling 70/6120 71/10654 3.6687458524110695e-16 4.138345321519686e-15 1.5570929765180455e-15 4893/71/817/5908/55109/54845/8546/22866/5605/5037/3717/10827/2244/3690/408/4296/5894/8826/1185/4140/3845/3265/4763/818/8805/55750/8844/7094/5594/7414/10533/23164/57085/6714/9061/2335/1445/2266/2243/369/801/57670/805/283455/3674/409/673/8315/816/56829/7450/60/9444/7529/5595/4000/27044/815/22906/8087/5604/10018/10142/54518/80853/10256/5906/808/9715/5245 70 Hepatitis_C_virus_genotype_1a R-HSA-156842 Eukaryotic Translation Elongation 88/6120 93/10654 4.0531749552339566e-16 4.5356957832379986e-15 1.70659998115114e-15 6158/6138/6206/6234/6191/6128/6132/1917/6129/1915/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6192/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6166/1938/6136/6125/1937/6232/6160/1933/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/1936/6152/51065/6141/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 88 Hepatitis_C_virus_genotype_1a R-HSA-194138 Signaling by VEGF 99/6120 107/10654 4.3727481247456237e-16 4.854783351095535e-15 1.8266598051154534e-15 5295/4893/857/5335/71/5579/5291/5578/8829/7423/1432/2534/9475/3690/5603/2475/6093/8440/9564/3845/3265/3071/8877/5062/5829/5879/26999/5290/5567/10006/5921/1500/9261/6714/2321/10810/10000/3728/7410/5580/2324/7409/23191/3685/3791/3710/1535/5600/6300/801/10787/253260/805/5170/4688/5590/653361/6461/5747/7424/5568/3315/10451/1793/10152/7867/64223/5566/1003/10163/55845/5063/998/208/79109/2185/387/60/5058/63916/25759/558/1495/1499/4690/207/7422/10458/9047/10768/8936/3320/4846/1398/9844/5228/5296/808/1536 99 Hepatitis_C_virus_genotype_1a R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 155/6120 182/10654 4.638747241373474e-16 5.109870008075468e-15 1.9226386592534795e-15 1912/23165/7068/7486/9112/6045/9212/80012/10274/348995/6613/57122/59348/23511/4929/28996/4792/3190/9759/9612/8856/1911/6790/6672/23279/1387/1789/23225/23512/165918/57332/7022/7067/7428/1107/5371/8924/4152/672/115426/9972/10499/6612/5914/8021/6117/11315/55746/7421/4286/10062/79677/7150/6670/3622/1788/51564/51588/7518/3619/7153/51602/2516/100532731/8517/332/10762/5465/1655/5970/2099/79902/2494/9656/9883/84733/3066/7157/7158/10155/9063/7155/7690/6396/129401/7703/4791/6015/8554/7020/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/5111/4927/10521/1616/2908/8243/142/9971/197370/1069/8086/7329/367/25942/9641/648/6095/23468/5905/81929/5893/1487/55143/9631/5468/7021/8204/3090/79023/23636/10735/3183/4306/53371/6996/23137/9688/7341/10401/2033/9126/3065/23314/6256/5987/7376/6294/8648/6304/8480/10891/7508/4193 155 Hepatitis_C_virus_genotype_1a R-HSA-9013694 Signaling by NOTCH4 79/6120 82/10654 5.645916627289088e-16 6.1711181740136536e-15 2.3219436802559776e-15 8454/5689/5682/182/23385/5705/5709/9978/5695/22938/5711/1387/4088/5683/5699/4853/5702/9794/388585/5696/5691/7314/5718/2648/5700/5707/55534/3280/84441/7534/102/5664/9861/8850/5698/5692/5713/5710/5719/6233/2324/5663/5706/10460/10046/5714/5688/5687/5708/59/4855/5704/83464/7311/55851/51107/5694/4851/5684/5720/23462/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/2033/55294/5716/3516/5693/5721 79 Hepatitis_C_virus_genotype_1a R-HSA-69239 Synthesis of DNA 108/6120 119/10654 7.421395504584994e-16 8.04935973958834e-15 3.0286504731261843e-15 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/143471/5705/5709/5422/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/6117/29882/10714/5696/5691/7314/996/5718/6118/23594/5700/122706/5707/64785/23198/898/3978/890/51433/9861/6502/5698/5692/5985/5713/119504/4175/5710/5984/7324/5719/64682/6233/23649/5424/4999/4172/8318/246184/4173/5706/8881/5714/5111/6119/5688/5687/5427/5708/81620/10393/5704/51343/23595/7311/25906/51659/5983/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/5426/4171/5715/5701/5685/5686/5716/5981/5693/5721 108 Hepatitis_C_virus_genotype_1a R-HSA-2990846 SUMOylation 159/6120 188/10654 7.479269984285698e-16 8.050206624307507e-15 3.0289691217999133e-15 1912/10054/23165/7068/7486/9112/6045/9212/80012/10274/348995/6613/57122/59348/23511/4929/28996/4792/3190/9759/9612/8856/1911/6790/6672/23279/1387/1789/23225/10055/23512/165918/57332/7022/7067/7428/1107/5371/8924/4152/672/115426/9972/10499/6612/5914/8021/6117/11315/55746/7421/4286/10062/79677/7150/6670/3622/1788/51564/51588/7518/3619/7153/51602/2516/100532731/8517/332/10762/5465/1655/5970/2099/79902/2494/9656/9883/84733/3066/7157/7158/10155/9063/7155/7690/6396/129401/7703/4791/6015/8554/7020/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/5111/4927/10521/1616/2908/8243/142/9971/197370/1069/8086/7329/367/25942/9641/648/6095/23468/5905/81929/5893/29843/1487/55143/9631/5468/7021/8204/3090/79023/23636/10735/3183/4306/53371/6996/23137/9688/7341/10401/59343/2033/9126/3065/23314/6256/5987/7376/6294/8648/6304/8480/10891/7508/4193 159 Hepatitis_C_virus_genotype_1a R-HSA-166520 Signaling by NTRKs 94/6120 101/10654 8.78079856471722e-16 9.37948937594794e-15 3.5291247819916103e-15 5295/627/9252/4893/5335/5291/1848/1785/5605/5898/1432/2534/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5879/5515/5607/161/5290/3667/5899/1849/5594/5528/9261/6714/5519/5598/4208/4909/4914/6195/1213/1211/5600/1175/6300/5781/1846/25920/4908/1173/5800/6464/2904/135/7074/160/673/6774/26052/7867/5802/2889/6654/5900/387/2549/1020/4916/7529/5595/25759/5516/1845/4915/5604/5045/10817/4205/57498/10818/6014/466/53358/4803/2002/1398/1385/5906/8851/5296/581 94 Hepatitis_C_virus_genotype_1a R-HSA-162599 Late Phase of HIV Life Cycle 123/6120 139/10654 8.979064347327013e-16 9.519158443406833e-15 3.581676637160914e-15 6884/23165/6875/51652/27243/6874/348995/57122/55048/5431/23511/5435/5433/2960/51271/23279/23327/29082/23225/2965/27183/5439/6873/9972/6881/2967/51616/8021/11198/904/51497/55746/92421/7314/137492/25978/51160/2959/404672/10015/91782/5438/10762/79720/51534/4836/9397/79902/9883/89853/83860/51510/2068/5902/5478/6233/7514/1025/6396/129401/6883/6829/2957/25920/4928/2963/5434/5903/55706/7175/79643/5436/6878/4331/4927/8148/2966/2962/54457/8812/128866/2071/5901/8086/7311/93343/6880/6908/7251/1104/6882/2961/5432/22916/155382/6877/5905/6917/81929/5440/902/9631/5430/5045/6749/79023/5441/23636/4686/7316/6872/53371/9688/6879/9525/2958/5437/6827/2968/138474/1022/8178/8480 123 Hepatitis_C_virus_genotype_1a R-HSA-141424 Amplification of signal from the kinetochores 90/6120 96/10654 1.0257031935666789e-15 1.0712900021696424e-14 4.030833602788353e-15 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/79902/3796/5519/81565/91687/11243/83540/7514/54820/6396/64946/9793/140735/220134/4928/5903/55055/80776/1783/401541/79172/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/79023/55920/1781/4085/55166/79003/5527/701/57551 90 Hepatitis_C_virus_genotype_1a R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 90/6120 96/10654 1.0257031935666789e-15 1.0712900021696424e-14 4.030833602788353e-15 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/79902/3796/5519/81565/91687/11243/83540/7514/54820/6396/64946/9793/140735/220134/4928/5903/55055/80776/1783/401541/79172/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/79023/55920/1781/4085/55166/79003/5527/701/57551 90 Hepatitis_C_virus_genotype_1a R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 119/6120 134/10654 1.4174945123953383e-15 1.469608281233402e-14 5.529545156712466e-15 5579/2153/7042/5175/3959/5578/5582/3082/29106/5267/7423/3920/374354/2244/7114/3309/3690/2162/87/10487/7040/5874/54863/350/7043/967/5054/5099/1072/3699/7018/6678/5340/813/7094/7414/10490/83706/7044/6810/7123/6694/3671/7273/22927/1191/9749/3273/27154/226/2335/1/5478/94121/22915/2266/7873/5154/7076/2243/801/805/928/351/51097/7424/2316/3674/5552/2157/7277/334/335/51706/308/78991/6403/197/81/9948/3481/5473/8407/7450/29789/10916/139322/5005/7422/5004/5196/3827/1950/2621/5216/5768/710/6647/1893/5265/7078/55664/5345/54676/2/948/88/1675/5341/3479/5155/51368/808/213/5660/7057/5627/6814/3700 119 Hepatitis_C_virus_genotype_1a R-HSA-5658442 Regulation of RAS by GAPs 67/6120 68/10654 1.8814881076958675e-15 1.9364220670446522e-14 7.285977766259833e-15 5689/4893/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/3845/3265/4763/5696/5691/7314/5718/10156/8831/5700/122706/5707/23198/5921/9861/5698/5692/5713/5710/5719/6233/200734/22821/9462/5706/84078/5714/64926/5688/5687/5708/5704/7311/5694/5684/5720/153090/5690/5717/9491/10197/7316/10213/5715/8437/5701/5922/5685/5686/5716/399473/5693/5721/161742 67 Hepatitis_C_virus_genotype_1a R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 156/6120 185/10654 2.4552823350417993e-15 2.5086580379774907e-14 9.439071677048566e-15 6158/5393/6138/6206/6234/6191/6128/6132/10557/6129/23404/6176/10528/84135/27340/27043/6224/6146/6154/88745/6202/51096/6169/55272/6175/6218/5394/6173/6167/23481/6192/51077/6156/117246/6143/6139/23160/26168/11340/3921/10607/11103/51388/6208/6170/22984/10813/9136/6203/23246/6147/8568/6222/1454/56902/51602/6134/6155/9724/6231/6142/23521/54555/10171/5822/6207/10969/6233/6188/79707/54881/1453/4691/23016/118460/200916/6122/6230/2091/55127/8602/6194/6166/10436/9277/84128/6136/6125/6232/134430/6160/92856/65083/6193/10200/6210/6229/6205/11056/9790/140801/6235/55720/6181/55759/705/7311/6223/25873/51010/26354/56915/51202/9045/57647/6187/6168/6157/6137/79050/22894/6144/9349/55813/4736/51121/6159/25879/6217/81887/6152/57050/51065/6141/55781/6164/6209/11224/6165/6130/6204/6228/10199/51013/6124/25926/83732/27341/6189/6135/6201/6161/54512/10885/6133/9188 156 Hepatitis_C_virus_genotype_1a R-HSA-156902 Peptide chain elongation 84/6120 89/10654 3.05102349174219e-15 3.033254658764133e-14 1.1412917865002786e-14 6158/6138/6206/6234/6191/6128/6132/6129/1915/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6192/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6166/1938/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 84 Hepatitis_C_virus_genotype_1a R-HSA-192823 Viral mRNA Translation 84/6120 89/10654 3.05102349174219e-15 3.033254658764133e-14 1.1412917865002786e-14 6158/6138/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6192/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/5611/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/2926/51121/6159/6217/6152/51065/6141/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 84 Hepatitis_C_virus_genotype_1a R-HSA-3371556 Cellular response to heat stress 84/6120 89/10654 3.05102349174219e-15 3.033254658764133e-14 1.1412917865002786e-14 23165/6782/573/7531/1915/817/9530/348995/472/57122/3313/23511/3305/23279/91582/1387/259217/23225/3309/9531/2475/3306/27000/9972/23411/8021/6117/3312/55746/51182/818/3303/6118/5594/3308/10049/10013/3337/10762/9261/79902/9883/2932/6396/129401/3297/57521/4928/5903/55706/7175/1410/4927/64223/6119/57805/3281/3310/7266/816/8086/3326/3304/10728/5595/815/81929/9631/116835/545/79023/23636/10808/53371/9532/9688/7415/3320/2033/6767/22824/9529/2288/8480 84 Hepatitis_C_virus_genotype_1a R-HSA-8868773 rRNA processing in the nucleus and cytosol 163/6120 195/10654 3.0547671031525314e-15 3.033254658764133e-14 1.1412917865002786e-14 6158/5393/6138/6206/6234/6191/6128/6132/10557/6129/23404/55226/6176/10528/84135/27340/27043/6224/6146/6154/88745/6202/51096/6169/55272/6175/6218/5394/6173/6167/23481/6192/51077/6156/117246/6143/6139/23160/26168/11340/3921/10607/11103/51388/6208/6170/22984/10813/9136/6203/23246/54433/6147/8568/27292/6222/1454/56902/51602/6134/6155/9724/6231/6142/23521/54555/10171/5822/6207/10969/6233/6188/79707/54881/1453/4691/23016/118460/200916/6122/6230/2091/55651/55127/8602/6194/6166/10436/9277/84128/6136/6125/4839/6232/134430/6160/92856/65083/6193/10200/6210/6229/6205/11056/9790/140801/6235/55720/6181/55759/705/7311/6223/25873/55505/51010/26354/56915/51202/9045/57647/6187/6168/6157/6137/79050/22894/6144/9349/55813/4736/51121/6159/25879/6217/81887/6152/57050/51065/6141/55781/6164/6209/11224/6165/6130/6204/1736/6228/10199/51013/6124/25926/83732/27341/6189/6135/6201/6161/54512/10885/6133/9188 163 Hepatitis_C_virus_genotype_1a R-HSA-1169091 Activation of NF-kappaB in B cells 66/6120 67/10654 3.2428290650331413e-15 3.1533717115149855e-14 1.1864870045565904e-14 8454/5689/4790/5579/5682/143471/5705/5709/5695/4792/5711/5683/5699/5702/4794/3551/5696/5691/7314/5718/8945/5966/5700/122706/5707/23198/10892/8517/5970/9861/5698/5692/5713/5710/5719/6233/5706/8915/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/84433/5690/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5716/5693/5721 66 Hepatitis_C_virus_genotype_1a R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 66/6120 67/10654 3.2428290650331413e-15 3.1533717115149855e-14 1.1864870045565904e-14 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 66 Hepatitis_C_virus_genotype_1a R-HSA-6802952 Signaling by BRAF and RAF fusions 66/6120 67/10654 3.2428290650331413e-15 3.1533717115149855e-14 1.1864870045565904e-14 4893/71/817/5908/55109/54845/8546/22866/5605/5037/3717/10827/2244/3690/408/5894/8826/1185/4140/3845/3265/818/8805/55750/8844/7094/5594/7414/10533/23164/57085/6714/9061/2335/1445/2266/2243/369/801/57670/805/283455/3674/409/673/816/56829/7450/60/9444/7529/5595/4000/27044/815/22906/8087/5604/10018/10142/54518/80853/10256/5906/808/9715 66 Hepatitis_C_virus_genotype_1a R-HSA-8854518 AURKA Activation by TPX2 71/6120 73/10654 3.3872989223996256e-15 3.249041823526172e-14 1.22248382161791e-14 7531/11190/203068/54801/79441/5116/5048/8655/6790/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/22974/3161/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 71 Hepatitis_C_virus_genotype_1a R-HSA-8939902 Regulation of RUNX2 expression and activity 71/6120 73/10654 3.3872989223996256e-15 3.249041823526172e-14 1.22248382161791e-14 8454/5689/7291/5682/143471/5705/5709/9978/5695/5711/5683/2101/1749/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/865/11059/2099/9861/2932/6502/5698/5692/5713/5710/5719/6233/133522/5706/579/5714/6772/5688/5687/2908/5708/4488/5704/7311/860/1750/5694/57154/5684/5720/10273/5690/5717/9491/6500/59269/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721/10891 71 Hepatitis_C_virus_genotype_1a R-HSA-72764 Eukaryotic Translation Termination 87/6120 93/10654 4.539601614326839e-15 4.3248907271627314e-14 1.6272825132437606e-14 6158/6138/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6192/6156/6143/6139/3921/6208/6170/29104/6203/6147/6222/2935/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/2107/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/23708/9045/6187/6168/6157/6137/6144/9349/4736/327/51121/6159/6217/6152/51065/6141/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 87 Hepatitis_C_virus_genotype_1a R-HSA-927802 Nonsense-Mediated Decay (NMD) 104/6120 115/10654 4.746695000369016e-15 4.4618933003468754e-14 1.678831073814726e-14 6158/9887/6138/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/65109/6173/6167/6192/6156/6143/5520/6139/23381/5518/3921/6208/6170/5515/6203/6147/6222/2935/6134/22794/6155/4116/6231/6142/23521/1981/6207/6233/6188/23049/5976/200916/6122/6230/6194/2107/6166/6136/6125/6232/6160/55110/6193/6210/6229/6205/140801/6235/6181/9939/7311/6223/25873/23708/9045/6187/6168/22916/6157/6137/10921/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/4686/6209/11224/6165/6130/6204/6228/6124/6189/23293/9775/6135/6201/6161/6133 104 Hepatitis_C_virus_genotype_1a R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 104/6120 115/10654 4.746695000369016e-15 4.4618933003468754e-14 1.678831073814726e-14 6158/9887/6138/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/65109/6173/6167/6192/6156/6143/5520/6139/23381/5518/3921/6208/6170/5515/6203/6147/6222/2935/6134/22794/6155/4116/6231/6142/23521/1981/6207/6233/6188/23049/5976/200916/6122/6230/6194/2107/6166/6136/6125/6232/6160/55110/6193/6210/6229/6205/140801/6235/6181/9939/7311/6223/25873/23708/9045/6187/6168/22916/6157/6137/10921/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/4686/6209/11224/6165/6130/6204/6228/6124/6189/23293/9775/6135/6201/6161/6133 104 Hepatitis_C_virus_genotype_1a R-HSA-69306 DNA Replication 113/6120 127/10654 5.401718704399288e-15 5.043988988876156e-14 1.8978502802490358e-14 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/143471/5705/5709/5422/9978/1869/4174/5695/84515/4998/5711/10926/5683/990/5699/5702/8900/51529/29945/51434/55388/6117/29882/10714/5696/5691/7314/996/5718/6118/23594/5700/122706/5707/64785/23198/898/3978/890/51433/9861/6502/5698/5692/5985/5713/119504/4175/5710/5984/7324/5719/64682/6233/23649/5424/4999/4172/8318/246184/4173/5706/8881/5714/5111/51053/6119/5688/5687/5427/5708/81620/10393/5704/51343/23595/7311/25906/51659/5983/5694/4176/1017/5684/5720/8317/5690/5717/9491/6500/10197/7316/10213/5426/4171/5715/5701/5685/5686/5716/5981/5693/5721 113 Hepatitis_C_virus_genotype_1a R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 74/6120 77/10654 7.673247846458448e-15 7.117947015464745e-14 2.6781973092902062e-14 5689/5682/51807/63943/143471/10381/5705/7278/5709/5695/5711/7846/113457/5683/5699/5702/5696/5691/7314/5718/79861/5700/122706/5707/23198/983/9861/5698/5692/5713/10376/5710/7157/5719/6233/84617/51512/10382/7277/5706/9133/891/5714/5688/5687/5708/347733/22919/5704/3326/7311/10383/5347/84790/5694/7280/5684/5720/5690/5717/9491/10197/112714/7316/10213/1026/5715/5701/5685/3320/5686/5716/5693/5721 74 Hepatitis_C_virus_genotype_1a R-HSA-114608 Platelet degranulation 114/6120 129/10654 1.2934573700734628e-14 1.192009733204956e-13 4.485053419449779e-14 2153/7042/5175/3959/3082/29106/5267/7423/3920/374354/2244/7114/3309/3690/2162/87/10487/7040/5874/54863/350/7043/967/5054/5099/1072/3699/7018/6678/5340/813/7094/7414/10490/83706/7044/7123/6694/3671/7273/22927/1191/9749/3273/27154/226/2335/1/5478/94121/22915/2266/7873/5154/7076/2243/801/805/928/351/51097/7424/2316/3674/5552/2157/7277/334/335/51706/308/78991/6403/197/81/9948/3481/5473/8407/7450/29789/10916/139322/5005/7422/5004/5196/3827/1950/2621/5216/5768/710/6647/1893/5265/7078/55664/5345/54676/2/948/88/1675/5341/3479/5155/51368/808/213/5660/7057/5627/3700 114 Hepatitis_C_virus_genotype_1a R-HSA-450294 MAP kinase activation 63/6120 64/10654 1.6574425221977536e-14 1.498017623835953e-13 5.636438091924751e-14 8454/3725/9252/4790/1848/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/23118/8517/5528/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/1846/79155/7867/64127/5602/3656/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/7316/7335/4205/466/23291/2002/5609/1385/5599 63 Hepatitis_C_virus_genotype_1a R-HSA-4608870 Asymmetric localization of PCP proteins 63/6120 64/10654 1.6574425221977536e-14 1.498017623835953e-13 5.636438091924751e-14 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/57216/5696/5691/7314/5718/2535/5700/122706/5707/1856/8322/8325/23198/9861/8321/5698/5692/5713/5710/5719/6233/7474/7855/7976/144165/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/50855/10197/64750/7316/10213/5715/5701/5685/5686/23513/5716/5693/5721/8324 63 Hepatitis_C_virus_genotype_1a R-HSA-380259 Loss of Nlp from mitotic centrosomes 68/6120 70/10654 1.6680054393066993e-14 1.498017623835953e-13 5.636438091924751e-14 7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 68 Hepatitis_C_virus_genotype_1a R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 68/6120 70/10654 1.6680054393066993e-14 1.498017623835953e-13 5.636438091924751e-14 7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 68 Hepatitis_C_virus_genotype_1a R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 72/6120 75/10654 2.170594767181315e-14 1.9370497605858572e-13 7.288339524712744e-14 5295/2250/5291/7039/3082/941/2064/145957/2534/9965/2264/9542/2885/8660/2252/2253/5879/1839/5290/3667/8823/2065/3815/2069/8074/2260/2249/6714/2099/2248/2247/5880/7409/2246/2251/5154/3932/118788/255324/5781/940/930/2263/4233/8503/5159/29851/3084/10718/5293/1956/2549/8822/685/8817/2100/2254/152831/1950/50852/26281/10818/2261/2255/391/2066/27006/942/5155/4254/5296/5156 72 Hepatitis_C_virus_genotype_1a R-HSA-187037 Signaling by NTRK1 (TRKA) 76/6120 80/10654 2.3614309309298316e-14 2.0940991274283412e-13 7.879253155833402e-14 5295/9252/4893/5335/5291/1848/1785/5605/5898/1432/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5515/5607/161/5290/3667/5899/1849/5594/5528/9261/6714/5519/5598/4208/4914/6195/1213/1211/5600/1175/6300/1846/1173/6464/135/160/673/6774/26052/7867/2889/6654/5900/387/7529/5595/25759/5516/1845/4915/5604/4205/57498/10818/6014/466/53358/4803/2002/1398/1385/5906/5296 76 Hepatitis_C_virus_genotype_1a R-HSA-909733 Interferon alpha/beta signaling 67/6120 69/10654 2.8351635216563702e-14 2.4834376796929e-13 9.344177607803075e-14 3443/5777/5770/3107/9021/11274/3662/3106/4599/684/3133/3429/91543/4938/5696/3445/10410/9636/2634/3444/103/3434/3433/3451/3448/3661/3439/10581/3452/4940/3437/6773/7297/5781/3430/3660/3446/3135/3665/10379/3455/4600/8638/3394/3663/6772/8651/3659/25939/3440/3454/3716/3456/3105/3441/51447/54739/2537/3449/8519/3664/6041/1958/4939/6059/3669/3134 67 Hepatitis_C_virus_genotype_1a R-HSA-1226099 Signaling by FGFR in disease 62/6120 63/10654 2.8533113766684385e-14 2.4834376796929e-13 9.344177607803075e-14 5295/4893/11052/2250/5335/9530/613/5431/6776/5435/5433/11064/5439/2264/2885/9846/2252/2253/3845/3265/7750/8805/26127/5290/8823/8074/2260/5438/2249/2248/399687/2247/2246/2251/6777/1523/2963/5434/5436/9208/6774/2263/6772/2962/6654/11160/2549/5432/22916/8822/5440/5430/8817/5441/2254/4686/26281/10818/2261/5437/2255/27006 62 Hepatitis_C_virus_genotype_1a R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 62/6120 63/10654 2.8533113766684385e-14 2.4834376796929e-13 9.344177607803075e-14 5689/11065/5682/7321/8697/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/5707/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 62 Hepatitis_C_virus_genotype_1a R-HSA-69615 G1/S DNA Damage Checkpoints 66/6120 68/10654 4.816708065716299e-14 4.1666002286257557e-13 1.5677241621704973e-13 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/993/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/1111/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 66 Hepatitis_C_virus_genotype_1a R-HSA-69563 p53-Dependent G1 DNA Damage Response 64/6120 66/10654 1.388188607814895e-13 1.1862702648600011e-12 4.4634581074239687e-13 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Hepatitis_C_virus_genotype_1a R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 64/6120 66/10654 1.388188607814895e-13 1.1862702648600011e-12 4.4634581074239687e-13 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Hepatitis_C_virus_genotype_1a R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 59/6120 60/10654 1.4529622862582178e-13 1.2051040138965219e-12 4.5343219335860177e-13 8454/5689/9134/5682/5705/5709/5753/5695/5711/5683/5699/5702/8900/5696/5691/7314/5718/5700/5707/898/890/9861/6502/5698/5692/5713/595/5710/5719/6233/1163/1019/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/5690/5717/1027/9491/6500/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721 59 Hepatitis_C_virus_genotype_1a R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 59/6120 60/10654 1.4529622862582178e-13 1.2051040138965219e-12 4.5343219335860177e-13 8454/5689/5682/9039/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/5970/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 59 Hepatitis_C_virus_genotype_1a R-HSA-5610780 Degradation of GLI1 by the proteasome 59/6120 60/10654 1.4529622862582178e-13 1.2051040138965219e-12 4.5343219335860177e-13 8454/5689/5682/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/83737/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/8650/9861/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/2735/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Hepatitis_C_virus_genotype_1a R-HSA-5610783 Degradation of GLI2 by the proteasome 59/6120 60/10654 1.4529622862582178e-13 1.2051040138965219e-12 4.5343219335860177e-13 8454/5689/5682/1452/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/9861/2932/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/2736/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Hepatitis_C_virus_genotype_1a R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 59/6120 60/10654 1.4529622862582178e-13 1.2051040138965219e-12 4.5343219335860177e-13 8454/5689/5682/1452/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/2737/9861/2932/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Hepatitis_C_virus_genotype_1a R-HSA-5621481 C-type lectin receptors (CLRs) 122/6120 142/10654 1.6776918064835685e-13 1.3833599106092582e-12 5.205027211250961e-13 8454/5689/4586/9252/4893/4790/5682/7321/727897/9039/29108/143471/5705/5530/5709/5695/4792/5711/1387/5683/2534/5699/3385/5702/5894/3845/7334/3265/3551/5062/5696/5691/7314/257397/5718/8945/4773/5700/122706/5707/5567/5336/4582/23198/23118/10892/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/3710/801/4791/805/5170/4772/5568/4775/3384/5706/56667/64581/6850/8915/5714/5566/5688/5687/4067/5708/5063/7189/5704/30835/7311/5971/5694/5058/997/1147/5684/5720/6885/84433/5690/3553/5532/5717/9491/6500/10197/7316/10213/94025/7335/10768/7322/5715/93978/5701/23291/5685/5686/2033/5534/200958/5716/808/5693/5721/2207 122 Hepatitis_C_virus_genotype_1a R-HSA-68949 Orc1 removal from chromatin 68/6120 71/10654 1.724297870311324e-13 1.4135232541505622e-12 5.3185197468599e-13 8454/5689/5682/143471/5705/5709/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/5696/5691/7314/5718/23594/5700/122706/5707/23198/890/9861/6502/5698/5692/5713/4175/5710/5719/6233/4999/4172/4173/5706/5714/5688/5687/5708/81620/5704/23595/7311/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 68 Hepatitis_C_virus_genotype_1a R-HSA-5676590 NIK-->noncanonical NF-kB signaling 58/6120 59/10654 2.498055687631925e-13 2.03598758356128e-12 7.660602778013328e-13 8454/5689/5682/9039/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 58 Hepatitis_C_virus_genotype_1a R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 75/6120 80/10654 2.7430200649457303e-13 2.222792121593954e-12 8.363473156277363e-13 3839/23165/5335/348995/57122/11274/23511/4734/23279/23225/1973/3836/4599/9972/8021/7334/4938/55746/7314/402569/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/1977/51191/6233/5610/4940/6396/129401/4928/3838/5903/55706/7175/2316/4600/3841/8638/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/7318/1974/5595/3837/81929/9631/79023/23636/7316/53371/9688/6041/4939/6059/5300/9775/5495/8480 75 Hepatitis_C_virus_genotype_1a R-HSA-5687128 MAPK6/MAPK4 signaling 82/6120 89/10654 2.9561344245224415e-13 2.38179973632951e-12 8.961754886973297e-13 2308/5689/3725/5897/5682/27327/143471/5705/5709/5695/4609/5711/5683/5699/5702/192669/4343/5062/5696/5691/7314/5879/5718/5700/122706/5707/5567/23198/3337/983/9861/5698/5692/5713/5710/8555/896/5719/6233/7514/26523/5568/3315/5706/5597/5714/5566/5688/5687/5708/5063/998/5704/7311/5694/5058/27161/5684/5720/2309/10642/5690/57690/5717/9491/10197/192670/5596/8550/7316/10213/5715/5701/5685/5686/8556/23112/5716/5896/8202/5693/5721 82 Hepatitis_C_virus_genotype_1a R-HSA-5610787 Hedgehog 'off' state 100/6120 113/10654 4.602765701865202e-13 3.687442977062463e-12 1.3874365512799415e-12 8454/5689/5682/11127/1452/51684/143471/10381/5705/7278/5709/9978/5695/107/5711/7846/113457/5683/5699/5702/83737/5696/5691/7314/5718/8945/79659/5700/122706/5707/5567/27152/23198/112/5573/2737/5727/8650/111/9861/2932/5698/5692/5713/10376/5710/5719/6233/23322/196883/115/84617/54903/10382/79809/5568/7277/5706/113/5714/5566/2736/5688/5687/5708/347733/55811/5577/5704/7311/10383/84790/5694/7280/109/5684/5720/2735/5575/6608/5690/5717/9491/6500/114/7289/10197/108/7316/10213/2778/5715/5701/5576/5685/5686/5716/8481/5693/5721 100 Hepatitis_C_virus_genotype_1a R-HSA-3371453 Regulation of HSF1-mediated heat shock response 66/6120 69/10654 4.841068803503552e-13 3.8347792207528136e-12 1.4428732566326378e-12 23165/6782/573/7531/9530/348995/472/57122/3313/23511/3305/23279/91582/259217/23225/3309/9531/3306/27000/9972/23411/8021/6117/3312/55746/51182/3303/6118/5594/3308/10049/3337/10762/9261/79902/9883/2932/6396/129401/3297/4928/5903/55706/7175/4927/6119/57805/3310/7266/8086/3304/5595/81929/9631/116835/545/79023/23636/10808/53371/9532/9688/6767/22824/9529/8480 66 Hepatitis_C_virus_genotype_1a R-HSA-8948751 Regulation of PTEN stability and activity 66/6120 69/10654 4.841068803503552e-13 3.8347792207528136e-12 1.4428732566326378e-12 5689/5682/1459/1460/143471/5705/5709/5695/1457/4734/11060/5711/5683/5699/2444/5702/8975/80351/5696/5691/7314/5718/5700/122706/5707/23198/9861/81847/5698/10000/5692/5713/5710/5719/6233/331/23608/5706/8658/5714/5688/5687/5708/208/5704/7311/5694/5684/5720/10273/207/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5728/5987/5716/5693/5721 66 Hepatitis_C_virus_genotype_1a R-HSA-72312 rRNA processing 166/6120 205/10654 4.985864734199495e-13 3.927413002916921e-12 1.4777276248377216e-12 6158/5393/6138/6206/6234/6191/6128/6132/10557/6129/23404/55226/6176/10528/84135/27340/27043/6224/6146/6154/88745/6202/51096/6169/55272/6175/6218/5394/6173/6167/23481/6192/51077/6156/117246/6143/6139/23160/26168/11340/3921/10607/11103/51388/6208/6170/22984/10813/60528/9136/6203/23246/54433/6147/8568/27292/6222/1454/56902/51602/6134/6155/9724/6231/6142/23521/54555/10171/5822/6207/10969/6233/6188/79707/54881/1453/4691/23016/118460/200916/6122/6230/2091/55651/55127/8602/6194/6166/3028/10436/9277/84128/6136/6125/4839/6232/134430/6160/92856/65083/6193/10200/6210/6229/6205/11056/9790/140801/6235/55720/6181/55759/705/7311/6223/25873/55505/51010/26354/56915/51202/9045/57647/6187/6168/6157/6137/79050/22894/6144/9349/55813/4736/51121/6159/25879/6217/81887/6152/57050/51065/6141/55781/6164/54931/6209/11224/6165/6130/6204/1736/6228/10199/51013/6124/25926/83732/27341/6189/6135/6201/6161/54512/10885/6133/9188 166 Hepatitis_C_virus_genotype_1a R-HSA-4641258 Degradation of DVL 56/6120 57/10654 7.376390563072311e-13 5.778172607739977e-12 2.1740940606949974e-12 5689/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/1855/5696/5691/7314/5718/5700/122706/5707/1856/23198/59349/9861/5698/5692/5713/5710/5719/6233/1857/5706/5714/5688/5687/5708/51339/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/23072/5693/5721 56 Hepatitis_C_virus_genotype_1a R-HSA-190236 Signaling by FGFR 80/6120 87/10654 7.697178748872854e-13 5.996144771221395e-12 2.2561082229903566e-12 5295/4893/2250/5335/54845/5431/5435/5433/8569/9965/5439/2264/7072/2885/7073/5518/2252/2253/3845/3265/23769/7314/5515/5290/8823/23768/5594/8074/2260/5438/3185/2249/6714/2248/4670/2247/6233/2246/2251/200734/5781/5725/2963/5434/6464/5436/673/2263/2962/23767/6654/7311/53834/2549/5432/22916/5595/5516/8822/10253/5440/23543/5430/3178/8817/10817/5441/2254/4686/7316/152831/26281/10818/2261/867/5437/2255/27006/3187/161742 80 Hepatitis_C_virus_genotype_1a R-HSA-5358351 Signaling by Hedgehog 126/6120 149/10654 8.044623354025492e-13 6.23237303800876e-12 2.3449914230357713e-12 8454/5689/5682/11127/22873/1452/51684/143471/10381/5705/7278/8452/5709/9978/5695/107/3549/5711/7846/113457/5683/408/5699/6400/5702/83737/6868/51009/6469/5696/5691/7314/5718/8945/79659/339745/5700/122706/5707/5567/10956/27152/23198/112/5573/2737/5727/8650/111/50846/9861/8405/2932/5698/5692/5713/10376/5710/2262/5719/6233/27248/23322/196883/115/84617/54903/91653/10382/79809/5568/409/79577/7277/5706/113/84447/5714/5566/2736/5688/5687/5708/347733/55811/5577/5704/7311/147111/10383/84790/5694/7280/109/57154/5684/5720/2735/5575/6608/5690/5717/9491/6500/114/7289/10197/108/64750/132884/7316/10213/2778/50937/7415/5715/5701/5576/5685/5686/5716/2121/8481/5693/5721/5034 126 Hepatitis_C_virus_genotype_1a R-HSA-5654738 Signaling by FGFR2 69/6120 73/10654 8.195519616066468e-13 6.314580687788917e-12 2.375922856771642e-12 5295/4893/2250/5335/54845/5431/5435/5433/8569/5439/7072/2885/7073/5518/2252/2253/3845/3265/7314/5515/5290/8823/5594/8074/5438/3185/2249/6714/2248/4670/2247/6233/2246/2251/5781/5725/2963/5434/6464/5436/673/2263/2962/6654/7311/2549/5432/22916/5595/5516/8822/10253/5440/23543/5430/3178/8817/10817/5441/2254/4686/7316/26281/10818/867/5437/2255/27006/3187 69 Hepatitis_C_virus_genotype_1a R-HSA-9009391 Extra-nuclear estrogen signaling 72/6120 77/10654 1.2107228426927714e-12 9.277821783678302e-12 3.490871354217144e-12 5295/2788/4893/857/2770/7039/2782/3845/3265/8877/2773/2787/1839/5290/4316/5594/2069/10681/4313/2792/6714/2099/10000/2785/595/2783/2784/2771/7514/2353/255324/801/2791/805/5170/5590/6464/5747/1903/3315/4318/8503/2786/208/1956/858/3480/5595/596/685/54331/2309/59345/207/6722/1027/51764/94235/2100/1950/55970/4314/346562/2793/3320/4846/2002/1385/5296/808/3276/2790 72 Hepatitis_C_virus_genotype_1a R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 55/6120 56/10654 1.2668628966699697e-12 9.603638087659449e-12 3.613462931079031e-12 5689/5682/26986/143471/5705/5709/5695/5711/5683/5699/5702/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/9861/5698/5692/5713/1981/5710/5719/6233/3315/5706/5714/5688/5687/5708/5704/7311/5694/3304/5684/5720/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 55 Hepatitis_C_virus_genotype_1a R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 55/6120 56/10654 1.2668628966699697e-12 9.603638087659449e-12 3.613462931079031e-12 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/51009/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/9861/5698/5692/5713/5710/5719/6233/27248/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 55 Hepatitis_C_virus_genotype_1a R-HSA-1169408 ISG15 antiviral mechanism 68/6120 72/10654 1.3560460758764177e-12 1.0224732443774058e-11 3.847155768318123e-12 3839/23165/5335/348995/57122/11274/23511/4734/23279/23225/1973/3836/4599/9972/8021/7334/55746/7314/402569/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/1977/51191/6233/5610/6396/129401/4928/3838/5903/55706/7175/4600/3841/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/7318/1974/5595/3837/81929/9631/79023/23636/7316/53371/9688/5300/9775/5495/8480 68 Hepatitis_C_virus_genotype_1a R-HSA-438064 Post NMDA receptor activation events 75/6120 81/10654 1.616467436502239e-12 1.2123505773766793e-11 4.561587838729724e-12 5563/4893/51807/817/53632/10381/7278/107/7846/113457/1741/1739/6196/1740/6197/3845/3265/814/5879/5923/818/57554/79861/5567/5594/51422/5573/2902/6714/10376/6195/5613/2906/801/2891/4747/805/5170/84617/3838/2904/10382/5568/7277/10645/5566/84254/2905/5571/27330/347733/3084/816/5577/5562/10383/84790/5564/5565/5924/7280/5595/815/5575/114/112714/5576/2903/4137/2066/1742/88/1385/808/8536 75 Hepatitis_C_virus_genotype_1a R-HSA-5678895 Defective CFTR causes cystic fibrosis 59/6120 61/10654 1.9393370628133233e-12 1.4468070151147015e-11 5.443753158774242e-12 5689/5682/143471/91319/5705/5709/5695/5711/5683/5699/6400/5702/51009/5696/5691/7314/5718/5700/122706/5707/10956/79139/91445/23198/9861/5698/5692/5713/5710/5719/10613/6233/27248/5706/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 59 Hepatitis_C_virus_genotype_1a R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 54/6120 55/10654 2.174966861123608e-12 1.5972412886376495e-11 6.009776853104708e-12 8454/5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/26271/5706/5714/5688/5687/5708/5704/51343/7311/5694/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 54 Hepatitis_C_virus_genotype_1a R-HSA-4641257 Degradation of AXIN 54/6120 55/10654 2.174966861123608e-12 1.5972412886376495e-11 6.009776853104708e-12 5689/5682/143471/5705/5709/5695/5711/5683/5699/8312/5702/80351/5696/5691/7314/5718/5700/122706/5707/23198/9861/81847/5698/5692/5713/5710/8313/5719/6233/5706/8658/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/5716/5693/5721 54 Hepatitis_C_virus_genotype_1a R-HSA-8941858 Regulation of RUNX3 expression and activity 54/6120 55/10654 2.174966861123608e-12 1.5972412886376495e-11 6.009776853104708e-12 5689/5682/5705/5709/5695/5711/5683/5699/5702/7040/5696/5691/7314/5718/5700/5707/865/6714/9861/5698/5692/5713/5710/5719/6233/1029/864/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/2033/5716/5693/5721/4193 54 Hepatitis_C_virus_genotype_1a R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 48/6120 48/10654 2.565986834914787e-12 1.8746328690310103e-11 7.053489854360801e-12 5295/5777/1437/5291/6776/3558/3717/2534/3563/2885/9846/1399/7314/3635/5290/1439/7534/3718/3567/6233/7525/7409/6777/5781/3562/6464/1438/6850/5566/8503/2889/4067/29760/3636/6654/7006/3716/7311/5293/3561/3568/7316/3560/3055/867/1398/5296/3559 48 Hepatitis_C_virus_genotype_1a R-HSA-1234174 Cellular response to hypoxia 70/6120 75/10654 3.242888905486178e-12 2.3569450292451087e-11 8.868236616196603e-12 5689/5682/64344/7321/3091/143471/5705/5709/9978/5695/5711/1387/5683/5699/126374/7428/5702/2056/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/405/768/112399/84962/5706/5714/10370/5688/5687/5708/5704/7311/2034/55662/5694/5684/5720/7422/5690/5717/9491/10197/7316/10213/8994/7322/5715/5701/5685/5686/2033/8453/5716/54583/5693/5721 70 Hepatitis_C_virus_genotype_1a R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 53/6120 54/10654 3.7325726019845315e-12 2.6851670248970357e-11 1.0103204035446853e-11 8454/5689/5682/143471/5705/5709/9978/5695/6790/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/23194/5693/5721 53 Hepatitis_C_virus_genotype_1a R-HSA-9604323 Negative regulation of NOTCH4 signaling 53/6120 54/10654 3.7325726019845315e-12 2.6851670248970357e-11 1.0103204035446853e-11 8454/5689/5682/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/5707/7534/9861/5698/5692/5713/5710/5719/6233/5706/10460/5714/5688/5687/5708/4855/5704/7311/5694/5684/5720/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721 53 Hepatitis_C_virus_genotype_1a R-HSA-167161 HIV Transcription Initiation 47/6120 47/10654 4.4817095929427164e-12 3.0527587082363433e-11 1.148630376223305e-11 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Hepatitis_C_virus_genotype_1a R-HSA-167162 RNA Polymerase II HIV Promoter Escape 47/6120 47/10654 4.4817095929427164e-12 3.0527587082363433e-11 1.148630376223305e-11 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Hepatitis_C_virus_genotype_1a R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 47/6120 47/10654 4.4817095929427164e-12 3.0527587082363433e-11 1.148630376223305e-11 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Hepatitis_C_virus_genotype_1a R-HSA-6802949 Signaling by RAS mutants 47/6120 47/10654 4.4817095929427164e-12 3.0527587082363433e-11 1.148630376223305e-11 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Hepatitis_C_virus_genotype_1a R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 47/6120 47/10654 4.4817095929427164e-12 3.0527587082363433e-11 1.148630376223305e-11 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Hepatitis_C_virus_genotype_1a R-HSA-73762 RNA Polymerase I Transcription Initiation 47/6120 47/10654 4.4817095929427164e-12 3.0527587082363433e-11 1.148630376223305e-11 2074/9112/5435/5928/2965/64425/1107/2967/2648/30834/404672/8850/57459/2068/3066/9533/5434/9015/79101/9219/5931/221830/7270/4331/9013/1108/2966/54815/2071/10849/57504/6908/53615/5440/902/9014/25885/54700/5441/51082/7343/5437/3065/2968/84172/1022/10919 47 Hepatitis_C_virus_genotype_1a R-HSA-73776 RNA Polymerase II Promoter Escape 47/6120 47/10654 4.4817095929427164e-12 3.0527587082363433e-11 1.148630376223305e-11 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Hepatitis_C_virus_genotype_1a R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 47/6120 47/10654 4.4817095929427164e-12 3.0527587082363433e-11 1.148630376223305e-11 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Hepatitis_C_virus_genotype_1a R-HSA-75953 RNA Polymerase II Transcription Initiation 47/6120 47/10654 4.4817095929427164e-12 3.0527587082363433e-11 1.148630376223305e-11 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Hepatitis_C_virus_genotype_1a R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 47/6120 47/10654 4.4817095929427164e-12 3.0527587082363433e-11 1.148630376223305e-11 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Hepatitis_C_virus_genotype_1a R-HSA-9649948 Signaling downstream of RAS mutants 47/6120 47/10654 4.4817095929427164e-12 3.0527587082363433e-11 1.148630376223305e-11 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Hepatitis_C_virus_genotype_1a R-HSA-5387390 Hh mutants abrogate ligand secretion 57/6120 59/10654 5.546031414698815e-12 3.741581002260923e-11 1.407806513728634e-11 5689/5682/143471/5705/5709/5695/3549/5711/5683/5699/6400/5702/51009/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/50846/9861/5698/5692/5713/5710/5719/6233/27248/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 57 Hepatitis_C_virus_genotype_1a R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 57/6120 59/10654 5.546031414698815e-12 3.741581002260923e-11 1.407806513728634e-11 6206/1965/6234/27335/6191/8668/6224/8662/26986/6202/6218/6192/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1978/1968/6230/8669/6194/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 57 Hepatitis_C_virus_genotype_1a R-HSA-111885 Opioid Signalling 82/6120 91/10654 6.3992784056559214e-12 4.2966583580832616e-11 1.6166598077446538e-11 2788/5331/2770/817/5578/5582/2775/5530/107/4988/2782/5499/5518/5143/814/2773/5515/2787/818/84152/5567/5594/10681/112/5573/5528/111/5443/2792/5519/2785/2783/2784/5613/2771/5332/5580/3710/196883/115/801/2791/805/3838/2781/5568/113/10645/5566/84254/23236/816/2786/5577/1020/5141/109/5516/5533/815/5321/54331/5575/59345/5532/51764/94235/114/5330/108/2779/5173/55970/10768/346562/2793/5576/5534/1385/5144/808/2790 82 Hepatitis_C_virus_genotype_1a R-HSA-72649 Translation initiation complex formation 56/6120 58/10654 9.370050480889707e-12 6.231967536818154e-11 2.3448388492395296e-11 6206/1965/6234/27335/6191/8668/6224/8662/26986/6202/6218/6192/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1968/6230/8669/6194/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 56 Hepatitis_C_virus_genotype_1a R-HSA-72702 Ribosomal scanning and start codon recognition 56/6120 58/10654 9.370050480889707e-12 6.231967536818154e-11 2.3448388492395296e-11 6206/1965/6234/27335/6191/8668/6224/8662/6202/6218/6192/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1968/6230/8669/6194/1983/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 56 Hepatitis_C_virus_genotype_1a R-HSA-180534 Vpu mediated degradation of CD4 51/6120 52/10654 1.0979867046420052e-11 7.134383656890449e-11 2.684381756679945e-11 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/920/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Hepatitis_C_virus_genotype_1a R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 51/6120 52/10654 1.0979867046420052e-11 7.134383656890449e-11 2.684381756679945e-11 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Hepatitis_C_virus_genotype_1a R-HSA-69610 p53-Independent DNA Damage Response 51/6120 52/10654 1.0979867046420052e-11 7.134383656890449e-11 2.684381756679945e-11 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Hepatitis_C_virus_genotype_1a R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 51/6120 52/10654 1.0979867046420052e-11 7.134383656890449e-11 2.684381756679945e-11 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Hepatitis_C_virus_genotype_1a R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 51/6120 52/10654 1.0979867046420052e-11 7.134383656890449e-11 2.684381756679945e-11 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/2932/5698/5692/5713/595/5710/5719/6233/1019/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Hepatitis_C_virus_genotype_1a R-HSA-69541 Stabilization of p53 55/6120 57/10654 1.5820518506645212e-11 1.0232537199252178e-10 3.850092384041134e-11 5689/5682/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/51230/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721/4193 55 Hepatitis_C_virus_genotype_1a R-HSA-2408557 Selenocysteine synthesis 83/6120 93/10654 1.6419787575155815e-11 1.0571644055237305e-10 3.977684661321092e-11 6158/6138/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6192/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/60678/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 83 Hepatitis_C_virus_genotype_1a R-HSA-451927 Interleukin-2 family signaling 44/6120 44/10654 2.3868670043944218e-11 1.5228427494100158e-10 5.729845059370273e-11 5295/5777/1437/5291/6776/84868/3558/3717/3563/2885/9846/3600/3965/3635/5290/1439/50615/3718/3567/3932/6777/59067/3562/6464/6775/1438/3581/6774/6850/6772/8503/3636/6654/3716/5293/2185/6655/3561/3578/3568/3560/5296/3559/3601 44 Hepatitis_C_virus_genotype_1a R-HSA-8948216 Collagen chain trimerization 44/6120 44/10654 2.3868670043944218e-11 1.5228427494100158e-10 5.729845059370273e-11 169044/256076/1280/1289/1300/1290/1303/1285/1296/255631/1294/7373/1284/1305/1307/1298/84570/1295/1288/1292/1293/57642/1302/1291/1310/1286/1287/1308/91522/1277/81578/340267/1282/85301/1299/136227/1301/1281/1297/1306/50509/131873/80781/1278 44 Hepatitis_C_virus_genotype_1a R-HSA-2682334 EPH-Ephrin signaling 82/6120 92/10654 2.5690377872080492e-11 1.631686162145653e-10 6.139379064736163e-11 71/2042/1947/1212/23385/2051/2045/10094/2050/79784/2047/2534/9475/1948/4628/8976/6093/163/1759/8440/3265/5062/5879/1072/161/10093/5921/2046/6453/4313/2902/2041/102/6714/5664/2043/7525/1942/7410/1213/1211/1175/10109/5663/1173/2904/5747/7074/1949/10627/1945/10451/4318/160/2049/8218/10092/4067/2044/5063/6386/998/2048/83464/10097/387/60/55851/51107/5058/3984/4627/3985/6383/10398/10552/4637/1946/10096/103910/10095/1969 82 Hepatitis_C_virus_genotype_1a R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 62/6120 66/10654 2.7317488400724982e-11 1.7272492665929248e-10 6.49894460890507e-11 5689/5682/64344/7321/3091/143471/5705/5709/9978/5695/5711/5683/5699/126374/7428/5702/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/112399/84962/5706/5714/5688/5687/5708/5704/7311/2034/5694/5684/5720/5690/5717/9491/10197/7316/10213/8994/7322/5715/5701/5685/5686/8453/5716/54583/5693/5721 62 Hepatitis_C_virus_genotype_1a R-HSA-5696398 Nucleotide Excision Repair 96/6120 111/10654 2.932910859913679e-11 1.8461626394992354e-10 6.946367826111346e-11 2074/10445/5982/6613/5431/5435/9978/5433/85015/10980/2965/5439/10987/2067/2967/6612/6117/7334/10714/7314/6118/83444/404672/9557/3150/86/5438/3978/1643/5985/10920/2068/5984/6233/93973/8607/7874/5424/5886/8451/8554/10450/5434/5436/7515/8450/4331/5111/2966/6119/5427/1161/1642/142/2071/1069/7329/51426/2873/7311/3980/60/8533/5983/5432/51138/7528/9318/6917/5440/902/27339/5430/5441/7336/2072/54778/7316/64708/5426/283899/7341/4798/5437/10401/2033/2968/56949/5887/9716/5981/57461/1022/8178/50813/7508 96 Hepatitis_C_virus_genotype_1a R-HSA-195721 Signaling by WNT 247/6120 331/10654 2.9905705826451135e-11 1.8740908984576045e-10 7.051450636973742e-11 2788/8454/56998/27123/9070/5689/857/7478/5579/5682/5331/1459/5526/1452/5578/1212/81029/5929/5582/27327/1460/55737/143471/5705/6657/2775/8452/5530/55366/5709/9978/5695/1457/9559/4609/5881/5711/1387/5683/324/5699/8724/8312/2782/5702/192669/57216/1855/6932/90780/163/79412/5518/4343/5593/25776/3845/6659/80351/5696/5691/4920/7314/5879/5515/2787/5718/51176/8945/2535/7476/161/6662/79971/51701/5700/122706/5707/1856/8549/7473/1454/8322/8325/23198/10681/9101/7471/8395/7534/5528/7091/89780/51699/83439/7477/2792/59349/7475/9861/81847/5519/2932/8321/9580/11197/7481/5698/5880/5692/6422/5713/2785/2783/23002/2784/5710/7482/284654/8313/5719/6233/7474/1857/7514/4040/7479/1213/3710/1211/7855/7089/331/8607/1175/26523/801/6658/2791/7976/7480/4221/805/123169/80326/5145/1173/144165/22943/7090/6597/864/4772/10023/4041/409/79577/283149/5706/160/23401/8658/5714/6934/10524/5688/5687/4919/607/23236/5708/51339/5529/7088/7483/2786/208/57680/5704/7311/387/5694/51384/55553/5516/57154/27161/815/5684/8295/5720/7472/54331/7015/6885/1487/1499/5525/59345/139285/207/8085/5690/5532/57690/5717/9491/50855/7484/6500/51764/94235/5330/10197/192670/64750/7316/10213/55970/54361/64321/5216/5715/5701/2793/1455/5685/5686/2033/54894/5534/3065/23112/23513/5527/1488/5716/23072/26108/808/9736/5693/5721/6259/8324/2790/5592 247 Hepatitis_C_virus_genotype_1a R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 49/6120 50/10654 3.224428591478356e-11 2.0117010238869388e-10 7.569222217536523e-11 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 49 Hepatitis_C_virus_genotype_1a R-HSA-5655253 Signaling by FGFR2 in disease 43/6120 43/10654 4.167688955673724e-11 2.588740716960331e-10 9.740390603568546e-11 5295/4893/2250/5335/5431/5435/5433/5439/2885/2252/2253/3845/3265/5290/8823/8074/5438/2249/2248/2247/2246/2251/2963/5434/5436/2263/2962/6654/2549/5432/22916/8822/5440/5430/8817/5441/2254/4686/26281/10818/5437/2255/27006 43 Hepatitis_C_virus_genotype_1a R-HSA-5358346 Hedgehog ligand biogenesis 61/6120 65/10654 4.491242223618057e-11 2.7592550380898305e-10 1.0381967444548523e-10 5689/5682/143471/5705/5709/5695/3549/5711/5683/5699/6400/5702/6868/51009/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/50846/9861/5698/5692/5713/5710/2262/5719/6233/27248/5706/84447/5714/5688/5687/5708/5704/7311/147111/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721/5034 61 Hepatitis_C_virus_genotype_1a R-HSA-9614085 FOXO-mediated transcription 61/6120 65/10654 4.491242223618057e-11 2.7592550380898305e-10 1.0381967444548523e-10 2308/857/2290/65018/57060/356/10971/7295/2810/84676/4089/1647/1387/4088/10628/4801/3630/56729/23411/2538/7534/847/5934/3484/5443/8850/10000/3066/604/2645/5105/7532/4303/23410/4287/4800/901/9314/10370/2908/6794/4852/6648/4087/208/25942/7529/27113/2309/10018/4802/207/1027/6720/1649/114907/1026/2033/3065/91584/10891 61 Hepatitis_C_virus_genotype_1a R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 53/6120 55/10654 4.500912473479866e-11 2.7592550380898305e-10 1.0381967444548523e-10 51807/10381/7278/1780/3305/8655/84516/832/7846/113457/3306/3312/51164/3303/79861/3337/10376/3301/10540/140735/84617/5241/11258/1783/10382/93661/10294/55860/830/7277/10671/1639/2908/347733/51143/3326/367/10383/84790/3304/7280/10728/829/1778/112714/4306/1781/2289/10121/3320/10963/55466/2288 53 Hepatitis_C_virus_genotype_1a R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 56/6120 59/10654 8.07517397164518e-11 4.929002294380824e-10 1.8545854097558308e-10 5689/5682/143471/5705/5709/5695/84515/4998/5711/5683/990/5699/5702/5696/5691/7314/5718/23594/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/4999/5706/5714/51053/5688/5687/5708/81620/5704/23595/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 56 Hepatitis_C_virus_genotype_1a R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 70/6120 77/10654 8.62924377731889e-11 5.244497295698118e-10 1.973293495357859e-10 1912/23165/7486/6045/80012/10274/348995/6613/57122/23511/1911/6672/23279/23225/165918/57332/5371/8924/672/9972/6612/8021/6117/55746/79677/51564/51588/7518/100532731/10762/79902/9656/9883/84733/9063/6396/129401/7703/6015/8554/4928/5903/55706/7175/1029/8535/5885/641/4927/8243/142/197370/1069/8086/7329/648/81929/5893/9631/79023/23636/10735/53371/6996/23137/9688/7341/9126/8480/7508 70 Hepatitis_C_virus_genotype_1a R-HSA-68867 Assembly of the pre-replicative complex 63/6120 68/10654 9.878331203044506e-11 5.977874247335946e-10 2.2492337593559664e-10 5689/5682/143471/5705/5709/1869/4174/5695/84515/4998/5711/5683/990/5699/5702/5696/5691/7314/5718/23594/5700/122706/5707/23198/9861/5698/5692/5713/4175/5710/5719/6233/4999/4172/4173/5706/5714/51053/5688/5687/5708/81620/5704/23595/7311/5694/4176/5684/5720/5690/5717/9491/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 63 Hepatitis_C_virus_genotype_1a R-HSA-5654743 Signaling by FGFR4 41/6120 41/10654 1.2703923372216153e-10 7.654928185822553e-10 2.88024173621095e-10 5295/4893/5335/8569/9965/2264/2885/5518/2253/3845/3265/7314/5515/5290/8823/5594/8074/2249/6714/2247/6233/2246/2251/5781/6464/673/6654/7311/2549/5595/5516/8822/10253/8817/10817/2254/7316/152831/26281/10818/867 41 Hepatitis_C_virus_genotype_1a R-HSA-169911 Regulation of Apoptosis 51/6120 53/10654 1.2768697134439475e-10 7.661218280663685e-10 2.882608446027994e-10 5689/5682/4976/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/79658/5701/5685/5686/5716/5693/5721 51 Hepatitis_C_virus_genotype_1a R-HSA-390466 Chaperonin-mediated protein folding 83/6120 95/10654 2.1157797824004967e-10 1.2640887682986018e-9 4.756257851605042e-10 2788/6000/9134/1459/2770/51807/10528/1460/10381/7278/2775/10576/1457/7846/113457/2782/10574/6468/10564/54461/10693/8877/2773/2787/79861/5204/10575/10681/898/10517/8786/2792/26985/2785/10376/2783/26190/2784/10238/7157/2771/2791/26224/84617/2629/2781/8237/10382/7277/6774/26272/26270/347733/55135/5082/2786/10383/60/84790/22948/7280/84261/9628/10694/8841/54331/59345/5203/51764/94235/2779/112714/7203/908/55970/346562/11328/2793/6950/3801/55294/26234/2790 83 Hepatitis_C_virus_genotype_1a R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/6120 52/10654 2.148231487214001e-10 1.2780617708741525e-9 4.808832642930742e-10 5689/5682/143471/472/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Hepatitis_C_virus_genotype_1a R-HSA-5674135 MAP2K and MAPK activation 40/6120 40/10654 2.2177539913273387e-10 1.31387946545023e-9 4.943600228345771e-10 4893/71/84292/5908/22866/5605/5037/2244/54756/3690/408/5894/8826/4140/3845/3265/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/28956/283455/3674/409/673/7450/60/7529/5595/5604/54518/10256/8649/5906 40 Hepatitis_C_virus_genotype_1a R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 88/6120 102/10654 2.640501631672922e-10 1.5577854814472052e-9 5.861320512500123e-10 8454/8792/7124/5689/5682/356/9039/143471/5705/10673/5709/5695/3604/7133/5711/5683/5699/5702/60401/8740/7187/51330/958/5696/5691/7314/5718/8945/23495/8744/5700/122706/5707/23198/8764/9020/8741/1896/9861/5698/5692/5713/5710/8718/9040/5719/6233/8742/4791/959/4055/8600/330/5706/5714/5688/5687/5708/5704/7311/5971/115650/5694/1147/4050/5684/5720/7186/5690/5717/9491/6500/10197/7316/10213/970/5715/7132/5701/329/23291/5685/5686/4049/5716/7293/5693/5721 88 Hepatitis_C_virus_genotype_1a R-HSA-388841 Costimulation by the CD28 family 64/6120 70/10654 3.105738907648869e-10 1.8246216082437105e-9 6.865317585329079e-10 5295/5777/5526/151888/941/3115/3113/3117/2534/2885/2475/5518/3127/5062/5879/5515/1326/5290/5133/8764/3126/5528/9020/6714/5519/29126/10000/1445/916/7525/7409/3932/5781/1493/940/253260/3120/5170/3123/80380/3122/920/64223/8503/4067/29851/5063/5529/998/208/79109/3125/5058/5516/9402/5525/3119/207/919/915/917/942/5527/5296 64 Hepatitis_C_virus_genotype_1a R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 57/6120 61/10654 3.2473289951136153e-10 1.8998895780540236e-9 7.148520696821413e-10 71/51517/147179/10094/8976/2885/3071/5879/26999/25/1072/10093/10006/4771/5594/4644/4641/10810/7410/7409/23191/10109/10787/2214/5747/2209/10451/1793/6850/10152/10092/4650/10163/55845/998/695/3326/10097/60/5058/63916/5595/3984/4690/4627/10458/919/10552/8936/917/3320/1398/10096/7454/9844/10095/2212 57 Hepatitis_C_virus_genotype_1a R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 49/6120 51/10654 3.6113945584210766e-10 2.0955005462443285e-9 7.884526131445625e-10 5689/5682/143471/5705/5709/5695/5711/4946/5683/5699/5702/5696/5691/5718/1728/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/5706/4947/5714/5688/5687/5708/4953/5704/5694/5684/5720/5690/51686/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 49 Hepatitis_C_virus_genotype_1a R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 49/6120 51/10654 3.6113945584210766e-10 2.0955005462443285e-9 7.884526131445625e-10 6206/1965/6234/27335/6191/8668/6224/8662/6202/6218/6192/3921/8665/6208/6203/8666/6222/8667/6231/8663/8894/6207/6233/51386/6188/1968/6230/8669/6194/6232/6193/6210/6229/6205/6235/6223/8664/6187/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 49 Hepatitis_C_virus_genotype_1a R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 76/6120 86/10654 3.661540380102959e-10 2.1158901376824476e-9 7.961243967091853e-10 5295/5335/71/51517/5291/2268/147179/10094/2534/8976/2885/3071/5879/26999/25/1072/5290/10093/10006/5336/4771/5594/4644/4641/6714/10810/7525/7410/5580/7409/23191/3710/10109/10787/2214/5747/2209/10451/1793/6850/10152/5337/10092/4650/10163/4067/55845/998/695/3326/10097/60/5058/63916/5595/3984/23646/4690/4627/10458/919/3055/10552/10768/8936/917/3320/1398/10096/7454/9844/5296/5581/5338/10095/2212 76 Hepatitis_C_virus_genotype_1a R-HSA-5632684 Hedgehog 'on' state 75/6120 85/10654 5.672399853648487e-10 3.2512535746521815e-9 1.2233160146507652e-9 5689/5682/11127/22873/1452/51684/143471/5705/8452/5709/9978/5695/3549/5711/5683/408/5699/5702/83737/6469/5696/5691/7314/5718/339745/5700/122706/5707/23198/2737/5727/8650/50846/9861/8405/5698/5692/5713/5710/5719/6233/91653/409/79577/5706/5714/2736/5688/5687/5708/5704/7311/5694/57154/5684/5720/2735/6608/5690/5717/9491/10197/64750/132884/7316/10213/50937/5715/5701/5685/5686/5716/2121/5693/5721 75 Hepatitis_C_virus_genotype_1a R-HSA-69002 DNA Replication Pre-Initiation 75/6120 85/10654 5.672399853648487e-10 3.2512535746521815e-9 1.2233160146507652e-9 5689/5682/143471/5705/5709/5422/1869/4174/5695/84515/4998/5711/10926/5683/990/5699/5702/55388/6117/5696/5691/7314/5718/6118/23594/5700/122706/5707/23198/9861/5698/5692/5713/4175/5710/5719/6233/23649/4999/4172/8318/4173/5706/5714/51053/6119/5688/5687/5427/5708/81620/5704/23595/7311/5694/4176/1017/5684/5720/8317/5690/5717/9491/10197/7316/10213/5426/4171/5715/5701/5685/5686/5716/5693/5721 75 Hepatitis_C_virus_genotype_1a R-HSA-1227986 Signaling by ERBB2 48/6120 50/10654 6.066191841212015e-10 3.448923587140702e-9 1.297691293705796e-9 5295/4893/5335/26469/5578/2064/5753/145957/2534/4145/9542/2885/3845/3265/7314/1839/5290/2065/2069/9101/6714/10000/6233/7525/5580/1729/6464/5782/10193/3084/208/6654/10718/7311/387/1956/2549/11140/8065/685/10273/207/7316/1950/51072/3320/2066/5581 48 Hepatitis_C_virus_genotype_1a R-HSA-5654736 Signaling by FGFR1 48/6120 50/10654 6.066191841212015e-10 3.448923587140702e-9 1.297691293705796e-9 5295/4893/2250/5335/8569/2885/5518/2253/3845/3265/23769/7314/5515/5290/23768/5594/8074/2260/2249/6714/2248/2247/6233/2246/2251/200734/5781/6464/673/23767/6654/7311/53834/2549/5595/5516/8822/10253/8817/10817/2254/7316/26281/10818/867/2255/27006/161742 48 Hepatitis_C_virus_genotype_1a R-HSA-420499 Class C/3 (Metabotropic glutamate/pheromone receptors) 38/6120 38/10654 6.757294681615382e-10 3.826419879950879e-9 1.4397279727474752e-9 50833/5726/2550/50832/259294/2912/259295/9568/2911/2914/259296/259289/50835/338398/2916/259293/54429/222545/80835/50840/2913/2918/50838/83756/259286/259287/50836/846/259290/80834/259292/50834/259285/2917/50831/50839/50837/2915 38 Hepatitis_C_virus_genotype_1a R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 43/6120 44/10654 8.074303286068356e-10 4.5539070533425524e-9 1.7134521499698743e-9 834/79370/55367/472/1387/51499/8738/7159/637/27166/23368/332/64065/8797/7157/1121/604/63970/839/317/5875/55240/5366/84883/147923/843/94241/8626/7161/10397/8795/665/27113/9540/8793/835/58484/3486/355/8794/124446/5876/581 43 Hepatitis_C_virus_genotype_1a R-HSA-448424 Interleukin-17 signaling 65/6120 72/10654 8.719851363054312e-10 4.898402558528518e-9 1.843071959311962e-9 8454/3605/3725/9252/4790/1848/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/23118/8517/5528/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/1846/79155/7867/64127/5602/3656/7189/112744/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/7316/7335/4205/466/23291/2002/5609/1385/5599 65 Hepatitis_C_virus_genotype_1a R-HSA-72202 Transport of Mature Transcript to Cytoplasm 74/6120 84/10654 8.774028608085226e-10 4.909277911666734e-9 1.8471639174916266e-9 23165/8683/6431/84271/199746/348995/57122/23511/81608/65109/23279/23225/9877/9972/8021/55746/7919/53981/6432/8563/6430/10762/22794/9785/11338/4116/79902/9883/51213/10250/26097/51362/1977/57187/6396/129401/79228/2733/84324/4928/5903/55706/7175/6428/55110/6429/4927/10898/10569/9295/10482/51692/8086/9939/6426/22916/10921/81929/9631/29894/79023/23636/4686/8189/53371/7307/9688/9984/10189/9775/84248/6427/8480/55339 74 Hepatitis_C_virus_genotype_1a R-HSA-180585 Vif-mediated degradation of APOBEC3G 51/6120 54/10654 1.0091314773330287e-9 5.624013371697907e-9 2.116090137615338e-9 5689/5682/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/60489/5706/5714/5688/5687/5708/5704/7311/5694/5684/8065/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Hepatitis_C_virus_genotype_1a R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 47/6120 49/10654 1.0181035175848262e-9 5.6516770070653735e-9 2.1264988514826043e-9 9134/57060/2810/1869/6790/25904/1647/8900/55571/55835/57472/144455/85456/29883/1263/7027/7832/898/5934/890/10769/983/7157/5325/79733/1820/4869/4850/891/5111/246175/4848/23019/1874/1017/25946/4849/1027/9337/1026/5933/28984/2033/995/10498/581/3276 47 Hepatitis_C_virus_genotype_1a R-HSA-75893 TNF signaling 42/6120 43/10654 1.3785327207118223e-9 7.62247504393596e-9 2.868030923586207e-9 7124/25999/7375/9530/8439/10616/6868/1540/3551/7314/257397/90268/81858/8737/55072/23118/841/8517/8887/7128/10454/6233/6610/8772/331/8717/84888/56928/330/27005/8567/7311/1147/7186/56957/6885/7316/7132/329/9099/55512/7185 42 Hepatitis_C_virus_genotype_1a R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 70/6120 79/10654 1.4120634456580209e-9 7.702800294071877e-9 2.898254086011367e-9 2074/5982/5431/5435/9978/5433/10980/2965/5439/10987/2067/2967/6117/10714/7314/6118/404672/3150/5438/3978/5985/10920/2068/5984/6233/7874/5424/8451/10450/5434/5436/7515/8450/4331/5111/2966/6119/5427/1161/1642/2071/51426/2873/7311/3980/8533/5983/5432/51138/9318/6917/5440/902/27339/5430/5441/2072/7316/64708/5426/5437/2033/2968/56949/9716/5981/57461/1022/8178/50813 70 Hepatitis_C_virus_genotype_1a R-HSA-6806834 Signaling by MET 70/6120 79/10654 1.4120634456580209e-9 7.702800294071877e-9 2.898254086011367e-9 5295/3675/4893/5770/5908/3082/1280/1289/3688/3910/1290/6456/30011/2885/3845/3265/1399/7314/5879/255631/3918/5290/8027/2060/284217/9101/6714/9146/6455/2335/64759/3909/6233/57610/5781/1302/6464/85440/5747/382/1277/3912/6774/4233/5795/2889/5771/3913/6654/5867/7311/2549/53916/85301/10048/7316/3915/1301/1281/3673/867/3914/200958/1398/5906/23163/50509/1278/10254/6457 70 Hepatitis_C_virus_genotype_1a R-HSA-186797 Signaling by PDGF 54/6120 58/10654 1.4149115433791603e-9 7.702800294071877e-9 2.898254086011367e-9 5295/4893/5335/5291/256076/1280/1289/6696/6776/1290/2885/8440/9564/3845/1285/3265/1399/56034/5290/5340/1284/5921/6778/1298/6714/1292/5154/1293/6777/5781/1291/1286/1287/5782/6774/6772/2889/5159/7058/6654/1282/4690/1299/5045/1281/1297/1398/5155/50509/5296/7059/131873/7057/5156 54 Hepatitis_C_virus_genotype_1a R-HSA-72187 mRNA 3'-end processing 54/6120 58/10654 1.4149115433791603e-9 7.702800294071877e-9 2.898254086011367e-9 8683/6431/84271/51585/199746/81608/1477/65109/9877/7919/53981/6432/8563/6430/11051/8106/22794/9785/11338/4116/1478/51213/10250/26097/51362/23283/10914/57187/79228/84324/6428/55110/6429/10898/10569/9295/51692/9939/6426/22916/1479/10921/79869/29894/4686/8189/10978/7307/9984/10189/9775/84248/6427/55339 54 Hepatitis_C_virus_genotype_1a R-HSA-2428924 IGF1R signaling cascade 50/6120 53/10654 1.6670927716714928e-9 9.0407723386800192e-009 3.4016791778236132e-9 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/2323/54106/5290/3667/8823/8074/2260/2249/2248/2247/8471/2246/2251/5781/30849/5170/6464/2322/5140/2263/3481/208/6654/2549/3480/8822/8817/2254/152831/5289/26281/10818/2261/2255/27006/3479/5296 50 Hepatitis_C_virus_genotype_1a R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 36/6120 36/10654 2.0583080623945834e-9 1.1119595279602922e-8 4.183856678551604e-9 4893/71/5908/22866/5605/5037/2244/3690/408/5894/8826/4140/3845/3265/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/283455/3674/409/673/7450/60/7529/5595/5604/54518/10256/5906 36 Hepatitis_C_virus_genotype_1a R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 69/6120 78/10654 2.1929458208686227e-9 1.1801731326048696e-8 4.440517049890663e-9 3443/4790/7321/9140/79132/9474/4792/177/3093/1387/64135/83737/7187/1540/3551/7314/3445/6283/8737/29110/4214/9636/841/8517/3444/8887/7323/5970/23586/7128/3451/3448/3661/3439/51191/6233/10010/55593/8772/3452/4791/3446/3665/351/54476/7706/843/3440/9246/7189/7311/7318/5094/9641/3456/1147/3441/7186/57506/3449/7316/4793/3146/7322/2033/6288/54941/6285/5300 69 Hepatitis_C_virus_genotype_1a R-HSA-2428928 IRS-related events triggered by IGF1R 49/6120 52/10654 2.750972472146987e-9 1.4748559641548485e-8 5.5492900778950635e-9 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/2323/54106/5290/3667/8823/8074/2260/2249/2248/2247/8471/2246/2251/5781/30849/5170/2322/5140/2263/3481/208/6654/2549/3480/8822/8817/2254/152831/5289/26281/10818/2261/2255/27006/3479/5296 49 Hepatitis_C_virus_genotype_1a R-HSA-8943724 Regulation of PTEN gene transcription 56/6120 61/10654 2.8414432205225163e-9 1.517588992779071e-8 5.710077285260559e-9 1912/3725/6591/1822/9112/6045/80012/1911/5928/23512/57332/1107/2475/1386/64121/23186/2146/51564/5594/84232/100532731/7101/84733/57459/3066/7157/8726/57521/6015/28956/389541/9219/8535/5931/1108/2122/64223/10014/54815/6009/55004/57504/648/23466/53615/5595/8841/5468/5978/57167/1958/8649/6615/3065/23028/10542 56 Hepatitis_C_virus_genotype_1a R-HSA-6783783 Interleukin-10 signaling 45/6120 47/10654 2.8601737999094812e-9 1.521828323725422e-8 5.726028183334176e-9 729230/7124/1437/3593/5743/941/3383/6349/3576/2920/1435/7133/3606/6347/3588/3569/3592/3587/6367/3976/3627/7076/7850/7297/3557/6351/6774/1440/3552/3716/1234/3586/3554/2208/3553/1230/2919/2357/6352/6348/6364/7132/942/6363/5724 45 Hepatitis_C_virus_genotype_1a R-HSA-216083 Integrin cell surface interactions 74/6120 85/10654 2.9639531137933377e-9 1.5711180039280477e-8 5.911485434712475e-9 3675/8174/960/3696/5175/256076/3383/1280/1289/7448/6696/1300/3688/3693/1290/2244/3690/3694/2200/3385/1285/1296/3655/1294/375790/7412/1284/1305/1307/50848/3672/1298/999/2335/1295/1288/2266/3685/1292/2243/3791/1293/1291/1286/1287/91522/3674/3684/3384/83700/3678/1277/3695/4060/7450/3676/3371/1282/1299/3339/1281/1297/3673/682/8516/50509/3687/3680/131873/80781/7057/1278/3689/3682 74 Hepatitis_C_virus_genotype_1a R-HSA-170834 Signaling by TGF-beta Receptor Complex 65/6120 73/10654 3.4834770355816484e-9 1.8395889963183987e-8 6.921633849529474e-9 7321/25805/4738/9372/8239/9612/4609/4089/22938/23327/4088/5499/1030/9110/7040/904/7314/5054/7027/6497/51592/50848/7323/6667/4092/11171/7046/2280/9958/9040/6233/7514/1025/57530/5500/4221/5590/3726/5501/1024/60436/23645/8812/1874/142/4087/7048/7311/387/57154/51377/10273/5045/50855/23370/64750/54778/7316/9611/5933/867/3065/6498/56288/25937 65 Hepatitis_C_virus_genotype_1a R-HSA-195258 RHO GTPase Effectors 238/6120 327/10654 3.859298075899686e-9 2.03045159963379e-8 7.639773096046511e-9 55839/11130/64837/71/6249/51517/5579/9735/7531/5526/51807/10811/10971/5578/9212/388/7533/2810/147841/147179/348995/10381/57122/6280/7278/1780/23122/3688/5048/57405/8655/10094/23279/1432/2017/2491/7846/113457/79784/9475/1060/4628/11004/8976/1855/2885/23433/6093/9184/8826/10499/5518/23332/25909/3071/10726/81930/5062/55746/5879/5515/85415/26999/25/79682/1072/10403/79861/4638/25936/4659/10093/1856/10006/4771/389/5594/3619/64105/7534/94274/332/5528/6714/79902/3796/5519/81565/999/10810/5880/91687/11243/10376/23002/11113/83540/5580/1857/128239/9055/23191/7514/54820/29984/1729/6396/1535/5600/801/64946/9793/30849/10109/5586/140735/5500/10787/4221/805/3831/220134/5170/84617/4928/4688/5590/114793/5903/653361/55055/5747/80776/1783/401541/2316/7532/10382/10627/79172/7277/79980/6232/5501/10152/6279/54821/10092/9183/10163/1062/699/752/347733/22919/55845/5063/3895/5529/51143/998/695/10788/354/10097/57120/367/10383/5347/387/60/84790/84643/5058/4660/7280/7529/5595/1778/5516/5905/81929/3984/27035/54908/55143/1495/1499/5525/4690/1058/991/79019/4627/348235/80152/10458/1063/3985/6722/8379/1027/1080/23421/79023/55920/30851/112714/1781/10398/4085/5289/5585/5216/10552/81624/55166/8936/4637/995/79003/391/23028/1742/5527/10096/7454/701/23380/9928/29941/3799/103910/57551/5300/808/10095/1536 238 Hepatitis_C_virus_genotype_1a R-HSA-2132295 MHC class II antigen presentation 101/6120 123/10654 4.446036231634371e-9 2.3304502180685736e-8 8.768547293068766e-9 64837/162/11127/51807/10484/1785/10381/7278/1780/3115/1509/8655/84516/832/285643/3113/10112/972/7846/5476/3117/113457/9632/6456/11004/163/1759/3127/81930/51164/161/79861/29127/3126/22872/3796/10437/56992/10376/10540/3835/51128/1213/1211/9493/6396/1175/7879/140735/8907/1508/1514/3902/3831/3120/1173/84617/11258/6712/1783/10382/10802/93661/821/55860/830/3123/3832/7277/160/10671/3122/1639/26052/1062/347733/51143/9871/10383/24137/84790/84643/3125/22920/1075/7280/829/1778/114876/164/9371/3119/10120/112714/1512/1781/10121/1520/3799/375/10427 101 Hepatitis_C_virus_genotype_1a R-HSA-1442490 Collagen degradation 58/6120 64/10654 5.123047145387673e-9 2.6753690648135628e-8 1.0066338250586306e-8 256076/1280/1289/1300/1509/1290/1303/6868/1285/1296/1294/7373/4316/4320/1284/1305/4312/1307/4313/1298/102/84570/1295/1288/1292/1293/5645/1302/1291/1508/1514/1310/1286/1287/1308/8754/91522/4318/1277/4322/4321/4317/4319/1282/1299/1991/136227/5045/4314/1301/1281/1297/1306/50509/131873/80781/1278/4323 58 Hepatitis_C_virus_genotype_1a R-HSA-5654727 Negative regulation of FGFR2 signaling 34/6120 34/10654 6.267956620694015e-9 3.261187762058509e-8 1.2270538500018583e-8 2250/8569/2885/5518/2252/2253/7314/5515/8823/5594/8074/2249/6714/2248/2247/6233/2246/2251/5781/673/2263/7311/5595/5516/8822/10253/8817/2254/7316/26281/10818/867/2255/27006 34 Hepatitis_C_virus_genotype_1a R-HSA-5654741 Signaling by FGFR3 39/6120 40/10654 6.836014239243413e-9 3.530688673015829e-8 1.328456208435967e-8 5295/4893/2250/5335/8569/2885/5518/2253/3845/3265/7314/5515/5290/8823/5594/8074/2249/6714/2247/6233/2246/5781/6464/673/6654/7311/2549/5595/5516/8822/10253/8817/10817/2254/7316/26281/10818/2261/867 39 Hepatitis_C_virus_genotype_1a R-HSA-5675221 Negative regulation of MAPK pathway 39/6120 40/10654 6.836014239243413e-9 3.530688673015829e-8 1.328456208435967e-8 4893/1844/1850/1848/5526/1852/5605/5037/5894/1847/5518/4140/3845/3265/7314/5515/8844/1849/5594/5528/5519/80824/6233/1843/369/1846/11221/673/8315/5529/7311/5536/7529/5595/5516/5604/5525/7316/5527 39 Hepatitis_C_virus_genotype_1a R-HSA-163685 Integration of energy metabolism 90/6120 108/10654 7.286227037638706e-9 3.749481796741086e-8 1.4107792650671948e-8 2788/6804/5563/5313/5331/2740/2770/5578/2769/107/9495/2782/3630/2776/8826/5518/31/777/2181/6513/5515/2787/5567/3745/1131/51422/10681/112/5573/5528/111/2792/5519/51085/2785/2783/2784/2771/9370/7086/6844/2182/3710/196883/115/2791/9254/5568/2642/150/113/6616/5566/775/2864/32/23236/6794/2641/6514/2786/5577/773/5565/109/5516/54331/5575/59345/776/51764/94235/114/4082/5330/3790/108/55970/2778/2194/2767/10768/152/2793/5576/948/47/5906/9630/2790 90 Hepatitis_C_virus_genotype_1a R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 47/6120 50/10654 7.464691408515016e-9 3.827350867638608e-8 1.4400782659872032e-8 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/2209/5706/5714/5688/5687/5708/9902/5704/5694/5684/5720/5690/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721/4360 47 Hepatitis_C_virus_genotype_1a R-HSA-4615885 SUMOylation of DNA replication proteins 43/6120 45/10654 8.004935273254345e-9 4.0894778026408064e-8 1.5387060937147942e-8 23165/9212/348995/6613/57122/23511/6790/23279/23225/9972/6612/8021/55746/7150/51588/3619/7153/332/10762/79902/9883/7155/6396/129401/4928/5903/55706/7175/5111/4927/8086/7329/5905/81929/55143/9631/79023/23636/53371/9688/7341/10401/8480 43 Hepatitis_C_virus_genotype_1a R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 66/6120 75/10654 8.132353078439808e-9 4.1395732276534767e-8 1.557554988232439e-8 23165/8683/6431/84271/199746/348995/57122/23511/65109/23279/23225/9877/9972/8021/55746/7919/6432/8563/6430/10762/22794/9785/11338/4116/79902/9883/51213/10250/26097/51362/57187/6396/129401/79228/2733/84324/4928/5903/55706/7175/6428/55110/6429/4927/10569/9295/10482/8086/9939/6426/22916/10921/81929/9631/79023/23636/4686/53371/7307/9688/9984/10189/9775/84248/6427/8480 66 Hepatitis_C_virus_genotype_1a R-HSA-199977 ER to Golgi Anterograde Transport 122/6120 154/10654 8.265985302343138e-9 4.1924601713323114e-8 1.577454219000735e-8 6811/23256/6711/11014/126003/2153/51807/10484/7039/5861/10381/7278/1780/9570/8655/84516/832/3998/55738/7846/113457/9382/375056/9632/3630/6709/79090/10652/54732/51164/58485/1294/79861/10342/4253/128637/2801/10466/22872/1315/8615/11316/91949/8729/10376/1314/10540/51332/83696/51128/27095/6399/7109/378/6396/26286/1453/26958/140735/10959/84364/22820/84617/22796/11258/6712/1783/10382/10802/93661/55860/2157/830/7277/10671/9554/11196/1639/10282/6710/8775/81876/347733/51143/51693/23243/5537/9871/10383/84790/10945/1075/7280/829/1778/9919/10113/51399/11070/25839/55291/122553/83548/112714/1604/1781/57731/10121/2804/9527/22870/5265/10972/6708/4905/9276/287/375/84342/64689/288/10427 122 Hepatitis_C_virus_genotype_1a R-HSA-73856 RNA Polymerase II Transcription Termination 60/6120 67/10654 8.492944603128431e-9 4.292133294054153e-8 1.6149572080651686e-8 8683/6431/84271/51585/199746/81608/1477/65109/9877/7919/53981/6432/8563/6430/134353/11051/8106/22794/9785/11338/4116/1478/51213/10250/26097/51362/23283/6636/10914/57187/79228/84324/6635/6428/6637/55110/6429/10898/10569/9295/51692/9939/6426/22916/1479/10921/79869/29894/4686/8189/10978/7307/9984/10189/6634/9775/84248/6427/55339/6628 60 Hepatitis_C_virus_genotype_1a R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 50/6120 54/10654 9.891608950902274e-9 4.910974866469087e-8 1.8478024133635087e-8 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/2323/54106/5290/3667/8823/8074/2260/2249/2248/2247/8471/2246/2251/5781/30849/5170/6464/2322/5140/2263/3481/208/6654/2549/3480/8822/8817/2254/152831/5289/26281/10818/2261/2255/27006/3479/5296 50 Hepatitis_C_virus_genotype_1a R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 50/6120 54/10654 9.891608950902274e-9 4.910974866469087e-8 1.8478024133635087e-8 2074/5431/5435/9978/5433/10980/2965/5439/10987/2967/7314/404672/3150/5438/10920/2068/6233/7874/8451/10450/5434/5436/8450/4331/2966/1161/1642/2071/2873/7311/8533/5432/51138/9318/6917/5440/902/27339/5430/5441/7316/64708/5437/2033/2968/56949/9716/57461/1022/50813 50 Hepatitis_C_virus_genotype_1a R-HSA-74751 Insulin receptor signalling cascade 50/6120 54/10654 9.891608950902274e-9 4.910974866469087e-8 1.8478024133635087e-8 5295/3643/4893/2250/5291/9965/2264/3630/2885/8660/9846/2252/2253/3845/3265/2323/54106/5290/3667/8823/5594/8074/2260/2249/2248/2247/2246/2251/5781/30849/5170/6464/2322/5140/2263/208/6654/2549/5595/8822/8817/2254/152831/5289/26281/10818/2261/2255/27006/5296 50 Hepatitis_C_virus_genotype_1a R-HSA-8848021 Signaling by PTK6 50/6120 54/10654 9.891608950902274e-9 4.910974866469087e-8 1.8478024133635087e-8 4893/5770/2909/9021/27043/3091/2064/5753/145957/9542/9564/3845/3265/5829/7314/5879/120892/1839/2065/2069/898/202559/5921/6421/595/6233/1019/10657/1793/6774/2908/3084/10718/7311/2034/387/1956/63916/1017/685/207/55620/1027/10457/7316/1950/867/2066/1398/9844 50 Hepatitis_C_virus_genotype_1a R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 50/6120 54/10654 9.891608950902274e-9 4.910974866469087e-8 1.8478024133635087e-8 4893/5770/2909/9021/27043/3091/2064/5753/145957/9542/9564/3845/3265/5829/7314/5879/120892/1839/2065/2069/898/202559/5921/6421/595/6233/1019/10657/1793/6774/2908/3084/10718/7311/2034/387/1956/63916/1017/685/207/55620/1027/10457/7316/1950/867/2066/1398/9844 50 Hepatitis_C_virus_genotype_1a R-HSA-163359 Glucagon signaling in metabolic regulation 33/6120 33/10654 1.0936745074485128e-8 5.3731047230048886e-8 2.021683300033195e-8 2788/107/2782/2787/5567/112/5573/111/2785/2783/2784/196883/115/2791/5568/2642/113/5566/2641/2786/5577/109/54331/5575/59345/51764/94235/114/108/55970/2778/5576/2790 33 Hepatitis_C_virus_genotype_1a R-HSA-1839126 FGFR2 mutant receptor activation 33/6120 33/10654 1.0936745074485128e-8 5.3731047230048886e-8 2.021683300033195e-8 2250/5431/5435/5433/5439/2252/2253/8823/8074/5438/2249/2248/2247/2246/2251/2963/5434/5436/2263/2962/5432/22916/8822/5440/5430/8817/5441/2254/4686/26281/5437/2255/27006 33 Hepatitis_C_virus_genotype_1a R-HSA-9022692 Regulation of MECP2 expression and activity 33/6120 33/10654 1.0936745074485128e-8 5.3731047230048886e-8 2.021683300033195e-8 2290/79718/817/9212/27327/28996/9612/6907/192669/4204/4343/814/818/3066/26523/801/805/3930/5566/816/25942/27161/815/8841/57690/192670/9611/2874/3064/3065/23112/1385/808 33 Hepatitis_C_virus_genotype_1a R-HSA-1236394 Signaling by ERBB4 53/6120 58/10654 1.1743483574010723e-8 5.7494138331094164e-8 2.163273289949344e-8 5295/4893/2670/51741/23385/6776/4734/10413/145957/83737/6868/9542/2885/3845/3265/7314/6387/1839/5290/6678/2065/2069/23118/348/11059/6714/2099/5664/1447/2567/2566/3925/6233/5663/2554/6464/5241/3084/6654/83464/10718/7311/1956/55851/51107/685/7316/1950/9611/2066/6285/1742/11033 53 Hepatitis_C_virus_genotype_1a R-HSA-4086398 Ca2+ pathway 56/6120 62/10654 1.2884209488437415e-8 6.264391509895433e-8 2.3570386868139595e-8 2788/5331/5578/27327/2775/5530/2782/192669/6932/4343/5593/3845/2787/51176/2535/51701/8322/10681/83439/2792/7481/2785/2783/2784/7474/3710/7855/26523/801/2791/7976/805/5145/4772/6934/23236/2786/27161/815/54331/6885/1499/59345/5532/57690/51764/94235/5330/192670/55970/2793/5534/23112/808/2790/5592 56 Hepatitis_C_virus_genotype_1a R-HSA-8986944 Transcriptional Regulation by MECP2 56/6120 62/10654 1.2884209488437415e-8 6.264391509895433e-8 2.3570386868139595e-8 627/2290/79718/5770/817/9212/27327/6657/28996/9612/4988/6907/192669/4204/3654/4343/6750/814/818/2572/6446/54487/4208/3066/26523/801/2891/805/2904/3930/54715/4233/6515/5566/1392/816/5816/25942/27161/815/8841/5468/4986/57690/192670/114787/9611/2874/2289/2903/3064/5728/3065/23112/1385/808 56 Hepatitis_C_virus_genotype_1a R-HSA-109606 Intrinsic Pathway for Apoptosis 49/6120 53/10654 1.6028498802971994e-8 7.766386017934883e-8 2.922178837655231e-8 7531/55075/10971/7533/2810/1869/8655/836/90427/840/7159/637/578/23368/7027/5594/841/7534/4836/22900/598/10000/708/3002/7157/331/317/140735/1029/572/7532/6774/5366/56616/8626/208/7161/7529/5595/5533/27113/596/10018/842/207/54205/5534/581/5599 49 Hepatitis_C_virus_genotype_1a R-HSA-447115 Interleukin-12 family signaling 52/6120 57/10654 1.8787898152797868e-8 9.05904476850554e-8 3.408554358586632e-8 3593/5908/1265/3313/6175/3936/5898/3717/3181/4001/3594/4282/5062/3572/10148/1072/3592/6627/9049/27250/9987/3185/149233/3458/5478/302/51561/7297/6775/9446/3595/821/4478/6774/6772/998/9244/6648/3716/2939/246778/3586/829/5055/6647/6950/5306/9466/6845/375/5721/5034 52 Hepatitis_C_virus_genotype_1a R-HSA-2871796 FCERI mediated MAPK activation 32/6120 32/10654 1.9081817703873374e-8 9.05904476850554e-8 3.408554358586632e-8 3725/4893/5335/2885/3845/3265/5062/5879/5601/5336/5594/4214/7410/7409/2353/6464/2205/3937/10451/2206/6850/4067/5602/6654/5058/6416/5595/9402/27040/5609/5599/2207 32 Hepatitis_C_virus_genotype_1a R-HSA-392518 Signal amplification 32/6120 32/10654 1.9081817703873374e-8 9.05904476850554e-8 3.408554358586632e-8 2788/64805/2770/2769/5028/1432/2782/2776/2773/2787/10681/2792/6714/2785/2783/2784/2771/2791/6915/2786/5321/54331/59345/51764/94235/55970/2767/346562/2793/9630/2790/10672 32 Hepatitis_C_virus_genotype_1a R-HSA-397795 G-protein beta:gamma signalling 32/6120 32/10654 1.9081817703873374e-8 9.05904476850554e-8 3.408554358586632e-8 2788/5331/2782/2787/10681/2792/146850/10000/5294/2785/2783/2784/2791/5170/23236/998/695/2786/208/387/5058/54331/59345/207/9459/51764/94235/5330/55970/2793/23533/2790 32 Hepatitis_C_virus_genotype_1a R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 32/6120 32/10654 1.9081817703873374e-8 9.05904476850554e-8 3.408554358586632e-8 2788/2149/2769/408/2768/2782/2776/2787/5594/10681/2792/6714/2785/2783/2784/2151/2791/2147/409/2786/5595/54331/59345/51764/94235/55970/2767/2793/9630/9002/2790/10672 32 Hepatitis_C_virus_genotype_1a R-HSA-5673000 RAF activation 32/6120 32/10654 1.9081817703873374e-8 9.05904476850554e-8 3.408554358586632e-8 4893/5526/817/5605/3717/4296/5894/5518/4140/3845/3265/5515/818/8844/5528/6714/5519/369/801/805/673/8315/5529/816/7529/5516/815/5604/5525/5527/808/5245 32 Hepatitis_C_virus_genotype_1a R-HSA-5655302 Signaling by FGFR1 in disease 37/6120 38/10654 1.9814769666828046e-8 9.37544470813005e-8 3.527602936093725e-8 5295/4893/11052/2250/5335/9530/613/6776/11064/2885/9846/2253/3845/3265/7750/8805/26127/5290/8074/2260/2249/399687/2247/2246/2251/6777/1523/9208/6774/6772/6654/11160/2549/8822/2254/26281/10818 37 Hepatitis_C_virus_genotype_1a R-HSA-112399 IRS-mediated signalling 45/6120 48/10654 2.015452053526941e-8 9.504305670478217e-8 3.576088135812633e-8 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/2323/54106/5290/3667/8823/8074/2260/2249/2248/2247/2246/2251/5781/30849/5170/2322/5140/2263/208/6654/2549/8822/8817/2254/152831/5289/26281/10818/2261/2255/27006/5296 45 Hepatitis_C_virus_genotype_1a R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 58/6120 65/10654 2.0868201561858093e-8 9.808054734073305e-8 3.690376697254905e-8 2074/5982/5431/5435/9978/5433/2965/5439/2967/6117/10714/7314/6118/404672/3150/5438/3978/5985/2068/5984/6233/7874/5424/8451/10450/5434/5436/7515/8450/4331/5111/2966/6119/5427/1161/1642/2071/51426/7311/3980/5983/5432/6917/5440/902/27339/5430/5441/7316/5426/5437/2033/2968/56949/9716/5981/57461/1022 58 Hepatitis_C_virus_genotype_1a R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 72/6120 84/10654 2.111746211792949e-8 9.89223308514305e-8 3.7220496266607674e-8 10445/5982/6613/9978/85015/10980/2965/10987/2067/2967/6612/6117/7334/10714/7314/6118/83444/404672/9557/86/3978/1643/5985/10920/2068/5984/6233/93973/8607/5424/5886/8451/8554/7515/8450/4331/5111/2966/6119/5427/1642/142/2071/1069/7329/51426/2873/7311/3980/60/8533/5983/51138/7528/9318/902/7336/2072/54778/7316/64708/5426/283899/7341/4798/10401/2968/5887/5981/1022/50813/7508 72 Hepatitis_C_virus_genotype_1a R-HSA-168325 Viral Messenger RNA Synthesis 41/6120 43/10654 2.231278459357671e-8 1.0417558369848729e-7 3.9197084123954905e-8 23165/348995/57122/5431/23511/5435/5433/23279/23225/5439/9972/8021/55746/5438/10762/79902/9883/6396/129401/4928/2963/5434/5903/55706/7175/5436/4927/2962/8086/5432/81929/5440/9631/5430/79023/5441/23636/53371/9688/5437/8480 41 Hepatitis_C_virus_genotype_1a R-HSA-391251 Protein folding 84/6120 101/10654 2.8028940514074933e-8 1.3043170338232888e-7 4.907620642381021e-8 2788/6000/9134/1459/2770/51807/10528/1460/10381/7278/2775/10576/1457/7846/113457/2782/10574/6468/10564/54461/10693/8877/2773/2787/79861/5204/10575/10681/898/10517/8786/2792/26985/2785/10376/2783/26190/2784/10238/7157/2771/2791/6904/26224/84617/2629/2781/8237/10382/7277/6774/26272/26270/347733/55135/5082/2786/10383/60/84790/22948/7280/84261/9628/10694/8841/54331/59345/5203/51764/94235/2779/112714/7203/908/55970/346562/11328/2793/6950/3801/55294/26234/2790 84 Hepatitis_C_virus_genotype_1a R-HSA-437239 Recycling pathway of L1 44/6120 47/10654 3.305127581142397e-8 1.524015367024567e-7 5.7342571480431646e-8 9252/71/7430/51807/1785/10381/7278/285643/7846/113457/1808/6456/5962/163/6196/1759/6197/8986/161/79861/5594/8650/6714/10376/6195/1213/1211/1175/1173/84617/10382/7277/4478/160/26052/27330/347733/3897/10383/24137/60/84790/7280/112714 44 Hepatitis_C_virus_genotype_1a R-HSA-4570464 SUMOylation of RNA binding proteins 44/6120 47/10654 3.305127581142397e-8 1.524015367024567e-7 5.7342571480431646e-8 1912/23165/6045/80012/348995/6613/57122/23511/3190/1911/23279/23225/57332/9972/8021/55746/51602/100532731/10762/79902/9883/84733/6396/129401/7703/6015/4928/5903/55706/7175/8535/4927/8086/7329/648/81929/9631/79023/23636/3183/53371/9688/7341/8480 44 Hepatitis_C_virus_genotype_1a R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 31/6120 31/10654 3.3290548442806145e-8 1.524015367024567e-7 5.7342571480431646e-8 3725/9252/1848/1432/6196/5518/1386/6197/51231/5515/5601/1849/5594/5528/9261/5519/5598/4208/6195/2353/5600/1846/5602/5595/5516/1845/4205/466/2002/1385/5599 31 Hepatitis_C_virus_genotype_1a R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 31/6120 31/10654 3.3290548442806145e-8 1.524015367024567e-7 5.7342571480431646e-8 857/7478/5526/1452/324/8312/1855/5518/5515/2535/1856/7471/5528/89780/5519/2932/8321/1857/4040/7479/7855/10023/4041/23401/5529/5516/1499/5525/139285/1455/5527 31 Hepatitis_C_virus_genotype_1a R-HSA-5654733 Negative regulation of FGFR4 signaling 31/6120 31/10654 3.3290548442806145e-8 1.524015367024567e-7 5.7342571480431646e-8 8569/9965/2264/2885/5518/2253/7314/5515/8823/5594/8074/2249/6714/2247/6233/2246/2251/5781/673/7311/5595/5516/8822/10253/8817/2254/7316/152831/26281/10818/867 31 Hepatitis_C_virus_genotype_1a R-HSA-5685938 HDR through Single Strand Annealing (SSA) 36/6120 37/10654 3.369941516131106e-8 1.5327798508854385e-7 5.767234377351707e-8 83990/9156/1763/7486/5982/472/4683/84126/2067/672/6117/83695/6118/25/5888/116028/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/5983/5893/5883/10111/545/2072/5932/7156 36 Hepatitis_C_virus_genotype_1a R-HSA-6806003 Regulation of TP53 Expression and Degradation 36/6120 37/10654 3.369941516131106e-8 1.5327798508854385e-7 5.767234377351707e-8 11200/472/639/4194/8900/2475/5518/51230/7314/5515/6446/117584/890/983/5519/10000/900/7157/6233/7874/253260/5170/1029/80196/64223/1616/208/79109/7311/5516/1017/207/7316/9099/5527/4193 36 Hepatitis_C_virus_genotype_1a R-HSA-168253 Host Interactions with Influenza Factors 40/6120 42/10654 3.719128523999951e-8 1.6647527678856926e-7 6.263795408842025e-8 3839/23165/348995/57122/23511/23279/23225/3836/9972/8021/7040/55746/402569/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/3841/293/4927/10898/3840/8086/3837/81929/9631/79023/23636/53371/9688/8480 40 Hepatitis_C_virus_genotype_1a R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 40/6120 42/10654 3.719128523999951e-8 1.6647527678856926e-7 6.263795408842025e-8 56998/9070/5929/6657/324/6932/90780/25776/6659/7314/51176/8945/6662/7534/7091/83439/9580/6233/7514/7089/331/6658/4221/7090/283149/6934/607/7088/208/57680/7311/55553/1487/1499/207/8085/7316/64321/3065/26108 40 Hepatitis_C_virus_genotype_1a R-HSA-3928662 EPHB-mediated forward signaling 40/6120 42/10654 3.719128523999951e-8 1.6647527678856926e-7 6.263795408842025e-8 71/1947/2051/10094/2050/2047/2534/9475/1948/8976/6093/3265/5879/1072/10093/5921/6453/2902/6714/7525/10109/2904/5747/7074/1949/2049/10092/4067/998/2048/10097/387/60/5058/3984/3985/6383/10552/10096/10095 40 Hepatitis_C_virus_genotype_1a R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 40/6120 42/10654 3.719128523999951e-8 1.6647527678856926e-7 6.263795408842025e-8 83990/5892/9156/1763/7486/5982/472/4683/84126/672/6117/83695/6118/5888/116028/7517/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/5889/1111/79728/5983/5883/10111/675/545/10635/5932/7156/5890 40 Hepatitis_C_virus_genotype_1a R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 40/6120 42/10654 3.719128523999951e-8 1.6647527678856926e-7 6.263795408842025e-8 2788/6000/1459/2770/1460/2775/10576/1457/2782/10574/10693/2773/2787/10575/10681/8786/2792/2785/2783/2784/2771/2791/2781/5082/2786/22948/9628/10694/54331/59345/51764/94235/2779/7203/908/55970/346562/2793/6950/2790 40 Hepatitis_C_virus_genotype_1a R-HSA-3928665 EPH-ephrin mediated repulsion of cells 47/6120 51/10654 4.1896851128673374e-8 1.8636162404437547e-7 7.012038709844363e-8 71/2042/1947/1212/23385/2051/2045/2050/2047/2534/1948/163/1759/5879/161/2046/4313/2041/102/6714/5664/2043/7525/1942/7410/1213/1211/1175/5663/1173/7074/1949/1945/10451/4318/160/2049/8218/4067/2044/2048/83464/60/55851/51107/1946/1969 47 Hepatitis_C_virus_genotype_1a R-HSA-442755 Activation of NMDA receptors and postsynaptic events 78/6120 93/10654 4.189832256884186e-8 1.8636162404437547e-7 7.012038709844363e-8 5563/4893/51807/817/53632/10381/7278/107/7846/113457/1741/1739/6196/1740/6197/3845/3265/814/5879/5923/818/57554/79861/5567/5594/51422/5573/2902/6714/10376/6195/5613/2906/801/2891/4747/57576/805/5170/84617/3838/8573/2904/10382/5568/7277/10645/55327/5566/84254/2905/5571/27330/347733/3084/816/5577/5562/10383/84790/5564/5565/5924/7280/5595/815/5575/114/112714/5576/2903/4137/2066/1742/88/1385/808/8536 78 Hepatitis_C_virus_genotype_1a R-HSA-3000171 Non-integrin membrane-ECM interactions 53/6120 59/10654 5.0739951494558157e-8 2.2427376679412853e-7 8.438520228760043e-8 6385/5578/1280/1289/7448/1300/3688/3693/3910/1290/1605/3690/87/6382/7040/1285/3655/3918/375790/1284/284217/2247/2335/3909/1288/3685/5154/9672/3691/1302/1286/1287/8573/7276/1277/3912/3913/51399/3371/1282/3339/6383/3915/1301/1281/3673/3914/780/5155/50509/7057/1278/4921 53 Hepatitis_C_virus_genotype_1a R-HSA-380108 Chemokine receptors bind chemokines 53/6120 59/10654 5.0739951494558157e-8 2.2427376679412853e-7 8.438520228760043e-8 729230/7852/1237/6349/3576/6360/2920/2921/1236/6370/58191/1524/643/2833/6347/6387/10663/3579/6375/6846/6367/2826/6376/6354/3627/6346/9034/2829/1233/6366/6373/6357/10803/6351/3577/10563/10850/5473/4283/6356/56477/1234/57007/6374/1230/2919/5196/6352/6348/6364/6372/6363/1232 53 Hepatitis_C_virus_genotype_1a R-HSA-6804757 Regulation of TP53 Degradation 35/6120 36/10654 5.7270349997693643e-8 2.523474796773376e-7 9.494821183828158e-8 11200/472/4194/8900/2475/5518/51230/7314/5515/6446/117584/890/983/5519/10000/900/7157/6233/7874/253260/5170/1029/80196/64223/1616/208/79109/7311/5516/1017/207/7316/9099/5527/4193 35 Hepatitis_C_virus_genotype_1a R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 30/6120 30/10654 5.807533442633382e-8 2.543050358420208e-7 9.568476152622507e-8 4893/817/1741/1739/6196/1740/6197/3845/3265/5923/818/57554/5594/2902/6195/2906/801/4747/805/5170/2904/27330/816/5924/5595/815/1742/88/1385/808 30 Hepatitis_C_virus_genotype_1a R-HSA-5654696 Downstream signaling of activated FGFR2 30/6120 30/10654 5.807533442633382e-8 2.543050358420208e-7 9.568476152622507e-8 5295/4893/2250/5335/2885/2252/2253/3845/3265/5290/8823/8074/2249/2248/2247/2246/2251/5781/6464/2263/6654/2549/8822/8817/10817/2254/26281/10818/2255/27006 30 Hepatitis_C_virus_genotype_1a R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 39/6120 41/10654 6.191946260115372e-8 2.7029858287190943e-7 1.017024903079077e-7 23165/348995/57122/23511/81608/23279/23225/9972/8021/55746/53981/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10898/10482/51692/8086/22916/81929/9631/29894/79023/23636/4686/8189/53371/9688/10189/8480/55339 39 Hepatitis_C_virus_genotype_1a R-HSA-5619084 ABC transporter disorders 66/6120 77/10654 8.303071526276804e-8 3.6133737197686094e-7 1.3595672674605295e-7 5689/5682/143471/91319/5705/5709/5695/64240/5711/5683/5699/6400/5702/51009/5696/5691/7314/5718/5700/122706/5707/10956/79139/91445/64241/23198/9861/5698/215/5692/5713/5710/5719/10613/6233/27248/10058/5706/19/335/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/1244/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 66 Hepatitis_C_virus_genotype_1a R-HSA-3899300 SUMOylation of transcription cofactors 42/6120 45/10654 8.850615049818669e-8 3.8398052985367145e-7 1.444764367646513e-7 1912/6045/80012/6613/59348/28996/9612/1911/1387/57332/4152/115426/10499/6612/11315/3622/51588/100532731/1655/84733/10155/9063/7690/7703/6015/8554/8535/4869/10210/10521/1616/7329/25942/648/1487/8204/7341/10401/2033/6294/8648/10891 42 Hepatitis_C_virus_genotype_1a R-HSA-6807878 COPI-mediated anterograde transport 83/6120 101/10654 1.0036994639866504e-7 4.341154123377844e-7 1.6334017754254823e-7 6811/6711/11014/51807/5861/10381/7278/1780/9570/8655/84516/832/55738/7846/113457/9382/3630/6709/10652/54732/51164/79861/2801/10466/1315/8615/11316/91949/8729/10376/1314/10540/51332/378/26286/26958/140735/10959/84364/22820/84617/22796/11258/6712/1783/10382/93661/55860/830/7277/10671/1639/10282/6710/8775/81876/347733/51143/10383/84790/10945/7280/829/1778/11070/25839/83548/112714/1604/1781/57731/10121/2804/9527/10972/6708/4905/9276/287/375/84342/64689/288 83 Hepatitis_C_virus_genotype_1a R-HSA-5654732 Negative regulation of FGFR3 signaling 29/6120 29/10654 1.0130527471347864e-7 4.3682090931499967e-7 1.643581472898543e-7 2250/8569/2885/5518/2253/7314/5515/8823/5594/8074/2249/6714/2247/6233/2246/5781/673/7311/5595/5516/8822/10253/8817/2254/7316/26281/10818/2261/867 29 Hepatitis_C_virus_genotype_1a R-HSA-168276 NS1 Mediated Effects on Host Pathways 38/6120 40/10654 1.0296487331739501e-7 4.426233883461188e-7 1.6654138688051055e-7 3839/23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/402569/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/3841/4927/10898/3840/8086/3837/81929/9631/79023/23636/53371/9688/8480 38 Hepatitis_C_virus_genotype_1a R-HSA-174824 Plasma lipoprotein assembly, remodeling, and clearance 60/6120 69/10654 1.0649018577927307e-7 4.5638651048259884e-7 1.71719896441381e-7 29801/346/10577/51599/3931/55911/949/4023/163/1071/27329/9619/10062/161/8720/344/345/51129/84699/5567/5360/7436/9388/348/336/3069/338328/26119/116519/51128/1213/1211/1175/29116/1173/319/5568/160/341/338/19/335/3990/5566/255738/57552/3988/26291/4547/5045/91289/6646/649/3949/7376/2/4864/51360/213/5034 60 Hepatitis_C_virus_genotype_1a R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 62/6120 72/10654 1.4378501326938817e-7 6.143541476055676e-7 2.311567677440882e-7 8773/55763/5563/71/7531/11127/51807/10971/7533/2810/53632/10381/7278/60412/5898/7846/113457/51552/23433/5879/79861/51422/4644/7534/6810/5872/4641/10376/11336/6844/9882/801/4218/805/84617/7532/57186/10382/7277/5571/347733/208/5867/4012/10383/60/84790/5564/5565/22920/7280/7529/23265/6517/10890/9371/4627/207/112714/8766/808/6814 62 Hepatitis_C_virus_genotype_1a R-HSA-109704 PI3K Cascade 41/6120 44/10654 1.4450784032193222e-7 6.155772049967506e-7 2.3161695507156573e-7 5295/2250/5291/9965/2264/2885/8660/9846/2252/2253/2323/54106/5290/3667/8823/8074/2260/2249/2248/2247/2246/2251/5781/30849/5170/2322/5140/2263/208/2549/8822/8817/2254/152831/5289/26281/10818/2261/2255/27006/5296 41 Hepatitis_C_virus_genotype_1a R-HSA-5628897 TP53 Regulates Metabolic Genes 72/6120 86/10654 1.625403020652283e-7 6.903067045541323e-7 2.5973466151196914e-7 5563/7531/10971/9997/27327/7295/7533/2810/53632/7001/4514/192669/2475/4513/4343/64121/7296/9377/1329/2936/51422/7249/27244/7534/1351/2821/10000/2877/54541/7157/50484/9167/26523/2744/57521/28956/83667/389541/7532/1345/84987/64223/5571/10128/25824/6009/8626/208/55004/5562/1340/4697/5564/5565/7248/7529/27161/27165/207/57690/192670/2539/54205/143686/1350/8649/5728/23112/10542/1349/1327/5052 72 Hepatitis_C_virus_genotype_1a R-HSA-187687 Signalling to ERKs 33/6120 34/10654 1.6500676404959262e-7 6.986772892189958e-7 2.628841760107308e-7 4893/5605/5898/1432/5603/2885/3845/3265/1399/5899/5594/9261/6714/4914/5600/6300/6464/673/7867/2889/6654/5900/7529/5595/25759/5604/57498/10818/6014/53358/4803/1398/5906 33 Hepatitis_C_virus_genotype_1a R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 37/6120 39/10654 1.7100255042985254e-7 7.197420779286331e-7 2.708100091646369e-7 83990/5892/9156/1763/7486/5982/472/4683/84126/672/6117/83695/6118/5888/116028/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/5889/1111/5983/5883/10111/675/545/5932/7156/5890 37 Hepatitis_C_virus_genotype_1a R-HSA-76009 Platelet Aggregation (Plug Formation) 37/6120 39/10654 1.7100255042985254e-7 7.197420779286331e-7 2.708100091646369e-7 5770/5908/2244/3690/2885/9564/7094/10125/6714/2335/1445/2266/2243/2147/2814/5170/6464/5747/3674/1277/150/6850/6654/7450/7066/151/207/54518/2812/152/4352/1398/2811/10235/5906/2815/1278 37 Hepatitis_C_virus_genotype_1a R-HSA-418597 G alpha (z) signalling events 44/6120 48/10654 1.74915583849125e-7 7.340207536525781e-7 2.7618250081440793e-7 2788/5579/2770/5578/5582/5583/107/2782/2773/2787/10681/112/111/2792/5588/2785/2783/2784/2771/5580/196883/115/2791/2781/150/113/10287/8601/2786/109/151/54331/59345/51764/94235/114/108/55970/2778/346562/152/2793/5581/2790 44 Hepatitis_C_virus_genotype_1a R-HSA-9612973 Autophagy 95/6120 119/10654 1.8875186481187812e-7 7.897333216164634e-7 2.971449004066424e-7 51652/5563/2670/65018/1459/1915/27243/9140/8878/1460/53632/5116/55048/9474/8655/1457/51271/3043/3920/29082/55054/2475/84557/3312/11315/64121/92421/7314/137492/139341/25978/51160/60673/9821/51422/7249/10533/10013/91782/79720/192111/6714/8408/89853/123/55669/6233/9804/30849/57521/140735/28956/7405/79643/389541/22863/7416/26100/1068/64223/5571/128866/6009/3326/55004/7311/5562/93343/11345/55626/7251/5564/5565/401505/7248/155382/11337/10452/8897/1080/64419/100188893/7316/11152/5289/8678/56993/10226/8649/3320/81631/10542/23710/200894/7431 95 Hepatitis_C_virus_genotype_1a R-HSA-5696395 Formation of Incision Complex in GG-NER 40/6120 43/10654 2.3557129385897068e-7 9.827086518968896e-7 3.697537592803527e-7 6613/9978/85015/2965/2067/2967/6612/6117/7334/7314/6118/404672/9557/1643/2068/6233/5886/8451/8554/8450/4331/2966/6119/1642/142/2071/1069/7329/7311/902/7336/2072/54778/7316/7341/10401/2968/5887/1022/7508 40 Hepatitis_C_virus_genotype_1a R-HSA-422356 Regulation of insulin secretion 66/6120 78/10654 2.3658164302199212e-7 9.84012143542799e-7 3.702442107843007e-7 2788/6804/5331/2740/2770/5578/2769/9495/2782/3630/2776/8826/777/2181/6513/2787/5567/3745/1131/10681/112/5573/111/2792/2785/2783/2784/2771/6844/2182/3710/2791/9254/5568/150/6616/5566/775/2864/23236/2641/6514/2786/5577/773/54331/5575/59345/776/51764/94235/114/4082/5330/3790/55970/2778/2767/10768/152/2793/5576/948/5906/9630/2790 66 Hepatitis_C_virus_genotype_1a R-HSA-5357905 Regulation of TNFR1 signaling 32/6120 33/10654 2.7972414184429693e-7 1.1600324705895844e-6 4.3647358355890306e-7 7124/25999/7375/10616/1540/3551/7314/90268/81858/8737/55072/841/8517/8887/7128/6233/331/8717/84888/56928/330/27005/8567/7311/1147/7186/56957/7316/7132/329/9099/7185 32 Hepatitis_C_virus_genotype_1a R-HSA-3232142 SUMOylation of ubiquitinylation proteins 36/6120 38/10654 2.8362303406200555e-7 1.1727521349777941e-6 4.412594819177368e-7 23165/348995/57122/23511/23279/23225/7428/5371/9972/8021/55746/51588/10762/79902/9883/9063/6396/129401/8554/4928/5903/55706/7175/4927/8086/7329/81929/9631/79023/23636/53371/9688/7341/5987/8480/4193 36 Hepatitis_C_virus_genotype_1a R-HSA-3000170 Syndecan interactions 27/6120 27/10654 3.0819208286128686e-7 1.263229176844228e-6 4.753023554531475e-7 6385/5578/1289/7448/3688/3693/1290/3690/87/6382/7040/3655/2247/2335/3685/9672/3691/8573/1277/51399/3371/6383/1281/3673/50509/7057/1278 27 Hepatitis_C_virus_genotype_1a R-HSA-5654716 Downstream signaling of activated FGFR4 27/6120 27/10654 3.0819208286128686e-7 1.263229176844228e-6 4.753023554531475e-7 5295/4893/5335/9965/2264/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/2251/5781/6464/6654/2549/8822/8817/10817/2254/152831/26281/10818 27 Hepatitis_C_virus_genotype_1a R-HSA-912526 Interleukin receptor SHC signaling 27/6120 27/10654 3.0819208286128686e-7 1.263229176844228e-6 4.753023554531475e-7 5295/5777/1437/5291/3558/3717/3563/2885/9846/3635/5290/1439/3718/3567/3562/6464/1438/8503/3636/6654/3716/5293/3561/3568/3560/5296/3559 27 Hepatitis_C_virus_genotype_1a R-HSA-6782135 Dual incision in TC-NER 57/6120 66/10654 3.7496214791177355e-7 1.5324539958133355e-6 5.76600831571423e-7 2074/5982/5431/5435/9978/5433/2965/5439/2067/2967/6117/10714/7314/6118/404672/3150/5438/5985/2068/5984/6233/7874/5424/8451/10450/5434/5436/8450/4331/5111/2966/6119/5427/1161/1642/2071/51426/7311/5983/5432/6917/5440/902/27339/5430/5441/2072/7316/5426/5437/2033/2968/56949/9716/5981/57461/1022 57 Hepatitis_C_virus_genotype_1a R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 39/6120 42/10654 3.8338576829615993e-7 1.5623524083745243e-6 5.878504022551403e-7 23165/348995/57122/23511/81608/23279/23225/9972/8021/55746/53981/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10898/10482/51692/8086/22916/81929/9631/29894/79023/23636/4686/8189/53371/9688/10189/8480/55339 39 Hepatitis_C_virus_genotype_1a R-HSA-176187 Activation of ATR in response to replication stress 35/6120 37/10654 4.697617096343888e-7 1.908580839723172e-6 7.18122242045897e-7 5982/4174/84515/4998/10926/990/84126/55388/6117/6118/23594/63967/993/5985/4175/5984/5884/5810/4999/4172/8318/4173/6119/3364/144715/1111/23595/5983/4176/1017/5883/8317/545/4171/995 35 Hepatitis_C_virus_genotype_1a R-HSA-1251985 Nuclear signaling by ERBB4 31/6120 32/10654 4.737612013497236e-7 1.908580839723172e-6 7.18122242045897e-7 2670/51741/23385/6776/10413/145957/6868/9542/6387/1839/6678/2069/23118/348/6714/2099/5664/1447/3925/5663/5241/3084/83464/10718/55851/51107/685/9611/2066/6285/11033 31 Hepatitis_C_virus_genotype_1a R-HSA-2173789 TGF-beta receptor signaling activates SMADs 31/6120 32/10654 4.737612013497236e-7 1.908580839723172e-6 7.18122242045897e-7 25805/4738/9372/4089/23327/4088/5499/9110/7040/7314/4092/11171/7046/2280/9958/9040/6233/7514/5500/5501/23645/4087/7048/7311/57154/51377/10273/5045/64750/7316/867 31 Hepatitis_C_virus_genotype_1a R-HSA-381042 PERK regulates gene expression 31/6120 32/10654 4.737612013497236e-7 1.908580839723172e-6 7.18122242045897e-7 5393/1965/23404/3576/3309/4801/6347/11340/468/3484/8894/9451/8570/23016/118460/1968/5073/1051/4800/22926/51010/56915/167227/22894/440/9709/4802/1649/51013/467/54512 31 Hepatitis_C_virus_genotype_1a R-HSA-69481 G2/M Checkpoints 127/6120 168/10654 5.878951838498796e-7 2.361630225721739e-6 8.885865127015726e-7 5689/83990/5682/9156/1763/7531/7486/10971/5982/7533/2810/11200/143471/472/5705/5709/4174/5695/84515/4998/5711/4683/10926/5683/990/165918/84126/5699/5702/8924/55388/672/6117/7334/7465/5696/83695/5691/7314/5718/6118/23594/5700/122706/5707/51588/51720/23198/63967/7534/993/116028/983/9861/9656/5698/5692/5985/5713/4175/5710/7157/5984/5719/6233/7158/5884/5810/4999/4172/80010/8318/51512/7532/4173/5706/9133/580/11073/891/641/5714/6119/3364/10524/5688/5687/144715/5708/1111/5704/23595/7311/5983/5694/4176/7529/1017/5684/5720/5883/10111/8317/5690/5717/9491/545/10197/7336/29086/7316/10213/4171/5715/9088/7341/5701/5685/5686/995/5716/5932/9025/79184/7156/5693/5721 127 Hepatitis_C_virus_genotype_1a R-HSA-5688426 Deubiquitination 211/6120 297/10654 6.445299751094329e-7 2.581782002569035e-6 9.71420775882638e-7 5689/221937/5682/79594/7419/10474/7321/4738/7375/9817/10445/91833/6478/3091/143471/5705/11274/55031/8239/5709/5695/126119/4792/9986/11047/4609/4194/4089/55432/5711/7347/4088/5683/324/408/64135/5699/8724/8312/5702/8900/8975/57599/377630/672/6881/51616/7187/7040/7345/3054/1540/80351/100287404/5696/5691/7314/5718/3607/90865/2648/5700/122706/5707/8027/8737/83444/8767/171023/55611/51720/57646/23198/63967/9101/8517/86/993/890/7417/80124/983/4092/2099/1643/9861/23586/81847/8850/7128/7046/6502/5698/9146/5692/5713/5710/10454/8473/219333/7157/10869/9929/9958/8313/5719/6233/100287478/9804/55593/93973/10318/23770/8607/7874/5886/10600/23326/51651/93624/8237/4303/409/330/5706/4287/27005/7706/580/7416/79155/25862/9738/8658/84132/5714/79589/55288/64127/5688/9097/5687/5708/4087/63891/84749/7189/5704/7048/7311/367/114548/387/60/29761/5694/7528/9960/23358/23032/5684/8295/5720/10617/7186/56957/6885/991/51377/10392/5690/2625/57506/5717/9491/4086/1080/57695/10197/64750/29086/7316/10213/8314/8678/9100/7415/5715/283899/3416/5701/4798/329/9099/5685/5686/2033/5728/10868/5716/79184/78990/5887/9736/54764/5693/154/10254/5721/100287205/4193 211 Hepatitis_C_virus_genotype_1a R-HSA-72766 Translation 207/6120 291/10654 7.081133261235365e-7 2.8284413309750324e-6 1.0642287650701131e-6 6158/6138/5464/6206/1965/6234/27335/6191/6128/6132/1917/84545/6129/1915/26284/6176/55176/8668/27068/51318/6224/6146/6154/8662/26986/6202/64949/65003/6169/6175/219927/6218/6728/6173/64968/11222/6167/6192/6156/6143/1973/28973/51116/6139/6745/64975/3921/128308/8665/65005/6208/51073/6170/29104/65080/64981/6203/51253/10952/29093/6147/8666/6222/60488/64432/8667/6727/7818/6184/6183/58477/2935/6134/6747/6731/55699/6155/55157/10240/6729/6231/6142/7458/8663/23521/23107/8894/1981/6185/6207/64978/1977/6726/6233/28957/219402/9801/51386/6188/26589/10102/1978/64965/7284/200916/6122/1968/6230/8669/6194/2107/6166/1938/1650/1983/6136/6125/1937/23395/10056/6232/6160/6748/29927/1933/60559/6193/6210/6229/6205/54148/28972/140801/79587/6235/51263/6181/740/1975/23471/7311/6223/25873/8664/6730/23708/9045/6187/6168/6157/6137/1974/55037/29074/6144/10352/6182/9349/4736/8891/327/51121/65993/6159/56945/9521/6217/1936/6152/92399/79590/51065/6141/10480/116540/23480/6164/63931/8661/57176/64963/9669/6209/1964/11224/6165/10884/6130/6204/64969/51081/6228/7965/5018/55173/6124/90480/2193/3646/6189/9789/6135/6201/6161/51649/54998/6133 207 Hepatitis_C_virus_genotype_1a R-HSA-177929 Signaling by EGFR 44/6120 49/10654 7.566047247074621e-7 3.0135950899365018e-6 1.133894681095929e-6 5295/4893/5335/7039/55824/6456/6868/30011/2885/3845/3265/10252/5829/7314/1839/5290/8027/2060/2069/102/6714/9146/6455/1445/6233/29924/255324/5781/6464/5782/5796/998/6654/7311/1956/2549/10253/685/58513/7316/1950/867/10254/6457 44 Hepatitis_C_virus_genotype_1a R-HSA-2408522 Selenoamino acid metabolism 93/6120 118/10654 7.6448394084087e-7 3.036401004466554e-6 1.1424756299000698e-6 6158/6138/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6192/6156/6143/6139/3921/6208/6170/7296/6203/6147/4143/191/6222/4837/2936/6134/60678/6155/6231/6142/9061/23521/6207/6233/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/9521/6217/6152/11185/51065/6141/875/6164/6209/11224/6165/6130/6204/6228/7965/6124/6189/6135/6201/6161/6133 93 Hepatitis_C_virus_genotype_1a R-HSA-168638 NOD1/2 Signaling Pathway 34/6120 36/10654 7.76927473990866e-7 3.0599657495170976e-6 1.1513420961228947e-6 834/1432/5603/83737/3654/7334/1540/3551/7314/257397/8767/23118/841/8517/7128/837/10454/6233/5600/6300/5608/330/64127/3656/7189/7311/1147/6885/842/10392/835/7316/7335/329 34 Hepatitis_C_virus_genotype_1a R-HSA-177243 Interactions of Rev with host cellular proteins 34/6120 36/10654 7.76927473990866e-7 3.0599657495170976e-6 1.1513420961228947e-6 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/5902/7514/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/1104/5905/3837/81929/9631/79023/23636/53371/9688/8480 34 Hepatitis_C_virus_genotype_1a R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 34/6120 36/10654 7.76927473990866e-7 3.0599657495170976e-6 1.1513420961228947e-6 71/51517/147179/10094/8976/2885/3071/5879/26999/25/10093/10006/5594/10810/23191/10109/10787/5747/10152/10092/10163/55845/998/695/10097/60/5595/4690/10458/10552/8936/10096/7454/10095 34 Hepatitis_C_virus_genotype_1a R-HSA-1839124 FGFR1 mutant receptor activation 30/6120 31/10654 8.016189139321622e-7 3.139674079567635e-6 1.1813331363210811e-6 5295/11052/2250/9530/613/6776/11064/2885/9846/2253/7750/8805/26127/5290/8074/2260/2249/399687/2247/2246/2251/6777/1523/9208/6774/6772/11160/8822/2254/26281 30 Hepatitis_C_virus_genotype_1a R-HSA-5654687 Downstream signaling of activated FGFR1 30/6120 31/10654 8.016189139321622e-7 3.139674079567635e-6 1.1813331363210811e-6 5295/4893/2250/5335/2885/2253/3845/3265/23769/5290/23768/8074/2260/2249/2248/2247/2246/2251/5781/6464/23767/6654/2549/8822/10817/2254/26281/10818/2255/27006 30 Hepatitis_C_virus_genotype_1a R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 25/6120 25/10654 9.373229936014805e-7 3.59137342657089e-6 1.3512894415765052e-6 11065/7321/8697/51529/29945/51434/9184/29882/7314/996/51433/119504/7324/64682/6233/246184/8881/10393/7311/25906/991/7316/4085/4751/701 25 Hepatitis_C_virus_genotype_1a R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 25/6120 25/10654 9.373229936014805e-7 3.59137342657089e-6 1.3512894415765052e-6 9252/1848/1432/6196/5518/6197/51231/5515/1849/5594/5528/9261/5519/5598/4208/6195/5600/1846/5595/5516/1845/4205/466/2002/1385 25 Hepatitis_C_virus_genotype_1a R-HSA-392451 G beta:gamma signalling through PI3Kgamma 25/6120 25/10654 9.373229936014805e-7 3.59137342657089e-6 1.3512894415765052e-6 2788/2782/2787/10681/2792/146850/10000/5294/2785/2783/2784/2791/5170/2786/208/387/54331/59345/207/51764/94235/55970/2793/23533/2790 25 Hepatitis_C_virus_genotype_1a R-HSA-418592 ADP signalling through P2Y purinoceptor 1 25/6120 25/10654 9.373229936014805e-7 3.59137342657089e-6 1.3512894415765052e-6 2788/2769/5028/1432/2782/2776/2787/10681/2792/6714/2785/2783/2784/2791/2786/5321/54331/59345/51764/94235/55970/2767/2793/9630/2790 25 Hepatitis_C_virus_genotype_1a R-HSA-5654700 FRS-mediated FGFR2 signaling 25/6120 25/10654 9.373229936014805e-7 3.59137342657089e-6 1.3512894415765052e-6 4893/2250/2885/2252/2253/3845/3265/8823/8074/2249/2248/2247/2246/2251/5781/2263/6654/8822/8817/10817/2254/26281/10818/2255/27006 25 Hepatitis_C_virus_genotype_1a R-HSA-5654708 Downstream signaling of activated FGFR3 25/6120 25/10654 9.373229936014805e-7 3.59137342657089e-6 1.3512894415765052e-6 5295/4893/2250/5335/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/5781/6464/6654/2549/8822/8817/10817/2254/26281/10818/2261 25 Hepatitis_C_virus_genotype_1a R-HSA-8854691 Interleukin-20 family signaling 25/6120 25/10654 9.373229936014805e-7 3.59137342657089e-6 1.3512894415765052e-6 11009/6776/3717/282618/50604/282617/3588/282616/55801/3718/6777/6773/7297/5781/6775/50616/53833/6774/6772/29949/116379/163702/3716/58985/53832 25 Hepatitis_C_virus_genotype_1a R-HSA-9006335 Signaling by Erythropoietin 25/6120 25/10654 9.373229936014805e-7 3.59137342657089e-6 1.3512894415765052e-6 5295/4893/5335/5291/6776/3717/2885/2056/8660/3845/3265/1399/5290/5336/5294/2057/7409/6777/6464/2889/4067/6654/5293/2549/23533 25 Hepatitis_C_virus_genotype_1a R-HSA-5685942 HDR through Homologous Recombination (HRR) 57/6120 67/10654 1.104308397579835e-6 4.219715015142459e-6 1.587709121039044e-6 83990/5892/9156/1763/7486/5982/472/80198/4683/84126/672/6117/10714/348654/83695/7314/6118/5888/116028/7517/84464/5985/5984/6233/5884/5810/5424/80010/580/11073/641/5111/6119/3364/10524/5427/144715/5889/5429/1111/79728/51426/146956/7311/5983/5883/10111/675/545/7316/79008/5426/10635/5932/7156/5890/5981 57 Hepatitis_C_virus_genotype_1a R-HSA-674695 RNA Polymerase II Pre-transcription Events 69/6120 84/10654 1.2577502674365266e-6 4.793048316447305e-6 1.803431393422502e-6 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/11198/904/51497/80349/2959/404672/5438/83860/2068/1025/23168/6883/6829/2957/123169/25920/85403/2963/5434/5436/9646/6878/79577/4331/8148/2966/2962/54457/8812/2071/6880/6908/6882/2961/5432/22916/55840/6877/6917/5440/902/6830/5430/6749/5441/4686/6872/6879/54623/2958/5437/6827/2968/138474/1022/8178 69 Hepatitis_C_virus_genotype_1a R-HSA-114452 Activation of BH3-only proteins 29/6120 30/10654 1.3549735430406718e-6 5.081150786402519e-6 1.911832770695685e-6 7531/10971/7533/2810/1869/8655/90427/7159/637/23368/7027/7534/10000/7157/140735/572/7532/5366/8626/208/7161/7529/5533/27113/596/10018/207/5534/5599 29 Hepatitis_C_virus_genotype_1a R-HSA-2424491 DAP12 signaling 29/6120 30/10654 1.3549735430406718e-6 5.081150786402519e-6 1.911832770695685e-6 5295/4893/5335/7305/5291/3824/54209/567/2534/3822/2885/3133/3845/3265/5879/5290/5336/7410/3932/6464/3937/10451/6850/22914/695/6654/9402/27040/5296 29 Hepatitis_C_virus_genotype_1a R-HSA-4090294 SUMOylation of intracellular receptors 29/6120 30/10654 1.3549735430406718e-6 5.081150786402519e-6 1.911832770695685e-6 7068/6613/4929/9759/8856/7067/6612/5914/7421/10062/51588/2516/5465/2099/2494/9063/8554/5241/2908/9971/7329/367/6095/5468/4306/7341/10401/6256/7376 29 Hepatitis_C_virus_genotype_1a R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 29/6120 30/10654 1.3549735430406718e-6 5.081150786402519e-6 1.911832770695685e-6 7124/7375/10616/1540/3551/7314/257397/81858/8737/55072/23118/8517/7128/10454/6233/331/8717/330/27005/7311/1147/7186/56957/6885/7316/7132/329/9099/7185 29 Hepatitis_C_virus_genotype_1a R-HSA-6804758 Regulation of TP53 Activity through Acetylation 29/6120 30/10654 1.3549735430406718e-6 5.081150786402519e-6 1.911832770695685e-6 64769/84289/29117/5928/1107/5371/8396/23774/3622/79837/27154/57459/10000/7994/3066/7157/5608/7862/9219/5931/1108/54815/208/53615/5305/207/2033/3065/5300 29 Hepatitis_C_virus_genotype_1a R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 29/6120 30/10654 1.3549735430406718e-6 5.081150786402519e-6 1.911832770695685e-6 11065/7321/65264/8239/55236/3093/7347/7328/7332/7314/90268/10477/92912/29089/7324/6233/7874/7326/7317/7327/7311/997/7319/7320/7316/54926/7322/55284/27338 29 Hepatitis_C_virus_genotype_1a R-HSA-452723 Transcriptional regulation of pluripotent stem cells 24/6120 24/10654 1.6344723461259418e-6 6.064752652730468e-6 2.2819226106578246e-6 6299/64344/79727/6657/55211/4089/27022/84891/2516/5460/2041/5087/2247/63978/2649/6774/9314/79923/4087/2034/7547/6997/27086/57167 24 Hepatitis_C_virus_genotype_1a R-HSA-5260271 Diseases of Immune System 24/6120 24/10654 1.6344723461259418e-6 6.064752652730468e-6 2.2819226106578246e-6 4790/10333/4792/929/51135/7187/3551/8517/5970/7096/4791/81793/7098/695/81622/23643/1147/7099/4615/7100/114609/948/7097/148022 24 Hepatitis_C_virus_genotype_1a R-HSA-5602358 Diseases associated with the TLR signaling cascade 24/6120 24/10654 1.6344723461259418e-6 6.064752652730468e-6 2.2819226106578246e-6 4790/10333/4792/929/51135/7187/3551/8517/5970/7096/4791/81793/7098/695/81622/23643/1147/7099/4615/7100/114609/948/7097/148022 24 Hepatitis_C_virus_genotype_1a R-HSA-6783589 Interleukin-6 family signaling 24/6120 24/10654 1.6344723461259418e-6 6.064752652730468e-6 2.2819226106578246e-6 23529/9021/3717/3569/133396/3572/3976/1271/3570/7297/5781/9180/3589/6774/6772/9244/386653/3716/1270/5008/3590/867/3977/1489 24 Hepatitis_C_virus_genotype_1a R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 48/6120 55/10654 1.6624786024901535e-6 6.152479867483245e-6 2.3149308347977275e-6 834/4790/7295/29108/1432/10628/5603/83737/3654/7334/1540/3551/7314/257397/8767/23118/841/8517/5970/24145/7128/837/598/10454/6233/5600/6300/5608/4791/351/330/64127/3656/7189/3326/7311/114548/1147/596/6885/842/10392/10910/835/58484/7316/7335/329 48 Hepatitis_C_virus_genotype_1a R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 45/6120 51/10654 1.800927250844042e-6 6.647401632696595e-6 2.501149998416636e-6 51807/10381/7278/1780/5048/8655/84516/832/636/7846/113457/51164/79861/23299/5870/10376/10540/140735/84617/11258/1783/10382/93661/55860/830/7277/10671/1639/347733/51143/10383/84790/5049/7280/829/22931/1778/5321/5050/112714/1781/22930/25782/10121/51560 45 Hepatitis_C_virus_genotype_1a R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic 148/6120 202/10654 1.8236138233667585e-6 6.699618282872081e-6 2.5207970246864722e-006 6811/11014/64837/11311/8674/11127/51807/53407/5861/10381/7278/1780/5048/9570/8655/84516/832/285643/55738/10112/636/7846/113457/3482/9382/11004/10228/83452/6293/27314/8675/339122/81930/10652/54732/7110/51164/60561/79861/10618/9321/29127/55275/23299/51209/10466/23647/9827/1315/22836/347517/3796/5870/11316/55614/56992/91949/8729/4074/10376/1314/10540/3835/3833/8677/378/9493/26286/26958/140735/10959/1523/3831/84364/22820/51542/84617/22796/11258/1783/27333/9265/55850/9585/10382/93661/55860/830/3832/7277/10671/9554/23303/1639/8775/81876/9183/9712/1062/146909/347733/662/10244/51143/9648/10383/24137/84790/54734/84643/10945/5049/57589/22920/7280/829/22931/1778/9609/55582/5321/9371/25839/23095/5050/83548/9950/112714/1781/22930/738/25782/10121/9367/10226/9341/6836/9527/9342/51560/143187/10972/4905/9276/3799/9266/375/84342 148 Hepatitis_C_virus_genotype_1a R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 39/6120 43/10654 1.8245768940587795e-6 6.699618282872081e-6 2.5207970246864722e-006 2788/107/554/2782/2787/5567/10681/112/5573/111/2792/2785/2783/2784/196883/115/2791/5568/359/113/5566/2786/5577/109/54331/5575/59345/51764/94235/114/108/8766/55970/2778/2793/5576/4645/551/2790 39 Hepatitis_C_virus_genotype_1a R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 42/6120 47/10654 1.8677957622826388e-6 6.822777266369225e-6 2.567136798992228e-6 8454/79718/3091/9978/9759/9612/4609/22938/1387/6907/9794/388585/7314/2648/9734/55869/51564/55534/3280/84441/10013/7091/8850/3066/6233/7089/7090/10046/1024/10014/7088/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 42 Hepatitis_C_virus_genotype_1a R-HSA-9020591 Interleukin-12 signaling 42/6120 47/10654 1.8677957622826388e-6 6.822777266369225e-6 2.567136798992228e-6 3593/5908/1265/3313/6175/3936/5898/3717/3181/4001/3594/4282/5062/1072/3592/6627/9049/27250/9987/3185/3458/5478/302/7297/6775/9446/3595/4478/998/6648/3716/2939/3586/829/5055/6647/6950/5306/6845/375/5721/5034 42 Hepatitis_C_virus_genotype_1a R-HSA-159227 Transport of the SLBP independent Mature mRNA 32/6120 34/10654 2.115202186559567e-6 7.666928234059099e-6 2.88475687194161e-6 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10482/8086/22916/81929/9631/79023/23636/4686/53371/9688/10189/8480 32 Hepatitis_C_virus_genotype_1a R-HSA-165054 Rev-mediated nuclear export of HIV RNA 32/6120 34/10654 2.115202186559567e-6 7.666928234059099e-6 2.88475687194161e-6 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/5902/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/1104/5905/81929/9631/79023/23636/53371/9688/8480 32 Hepatitis_C_virus_genotype_1a R-HSA-4085377 SUMOylation of SUMOylation proteins 32/6120 34/10654 2.115202186559567e-6 7.666928234059099e-6 2.88475687194161e-6 23165/348995/6613/57122/23511/23279/23225/9972/8021/55746/51588/10762/79902/9883/6396/129401/4928/5903/55706/7175/10210/4927/8086/7329/81929/9631/79023/23636/53371/9688/7341/8480 32 Hepatitis_C_virus_genotype_1a R-HSA-9006936 Signaling by TGF-beta family members 81/6120 102/10654 2.2565985543383238e-6 8.158471696453939e-6 3.069704916022983e-6 10272/7321/25805/4738/9372/91851/130399/8239/9612/4609/4089/22938/23327/4088/5499/1030/9110/7040/904/7314/5054/7027/11167/6497/51592/50848/7323/91/93/6667/4092/11171/7046/94/2280/9958/9040/6233/7514/1025/57530/4091/5500/4090/4221/4093/5590/9765/269/3726/5501/1024/60436/23645/8812/1874/142/4087/7048/7311/387/57154/9241/51377/10273/5045/50855/4086/23370/64750/659/54778/7316/9611/5933/867/3065/6498/657/56288/25937 81 Hepatitis_C_virus_genotype_1a R-HSA-162588 Budding and maturation of HIV virion 28/6120 29/10654 2.287816330356357e-6 8.208195994408303e-6 3.0884141703484773e-6 51652/27243/55048/51271/23327/29082/27183/92421/7314/137492/25978/51160/10015/91782/79720/51534/89853/51510/5478/6233/79643/128866/7311/93343/7251/155382/7316/9525 28 Hepatitis_C_virus_genotype_1a R-HSA-186763 Downstream signal transduction 28/6120 29/10654 2.287816330356357e-6 8.208195994408303e-6 3.0884141703484773e-6 5295/4893/5335/5291/6776/2885/8440/9564/3845/3265/1399/5290/5921/6778/6714/5154/6777/5781/6774/6772/2889/5159/6654/4690/1398/5155/5296/5156 28 Hepatitis_C_virus_genotype_1a R-HSA-8863795 Downregulation of ERBB2 signaling 28/6120 29/10654 2.287816330356357e-6 8.208195994408303e-6 3.0884141703484773e-6 26469/2064/145957/4145/9542/7314/1839/2065/2069/9101/10000/6233/5782/10193/3084/208/10718/7311/1956/11140/8065/685/10273/207/7316/1950/3320/2066 28 Hepatitis_C_virus_genotype_1a R-HSA-112043 PLC beta mediated events 47/6120 54/10654 2.5440113190032257e-6 9.104202943640986e-6 3.4255455644606624e-6 5331/2770/817/5578/5582/2775/107/814/2773/818/5567/5594/112/5573/111/5613/2771/5332/5580/3710/196883/115/801/805/3838/2781/5568/113/10645/5566/84254/23236/816/5577/109/815/5321/5575/114/5330/108/2779/10768/346562/5576/1385/808 47 Hepatitis_C_virus_genotype_1a R-HSA-112409 RAF-independent MAPK1/3 activation 23/6120 23/10654 2.8499385782622405e-6 1.0071211517167317e-5 3.789392015417938e-6 1844/1850/1848/1852/5605/3717/1847/3569/3572/1849/5594/983/80824/1843/3570/7297/5781/8682/1846/11221/3716/5595/5604 23 Hepatitis_C_virus_genotype_1a R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 23/6120 23/10654 2.8499385782622405e-6 1.0071211517167317e-5 3.789392015417938e-6 11065/7321/8697/51529/29945/51434/29882/7314/996/983/51433/119504/7324/64682/6233/246184/8881/891/10393/7311/25906/991/7316 23 Hepatitis_C_virus_genotype_1a R-HSA-428930 Thromboxane signalling through TP receptor 23/6120 23/10654 2.8499385782622405e-6 1.0071211517167317e-5 3.789392015417938e-6 2788/2769/2782/2776/2787/10681/2792/2785/2783/2784/2791/6915/2786/54331/59345/51764/94235/55970/2767/2793/9630/2790/10672 23 Hepatitis_C_virus_genotype_1a R-HSA-5654695 PI-3K cascade:FGFR2 23/6120 23/10654 2.8499385782622405e-6 1.0071211517167317e-5 3.789392015417938e-6 5295/2250/2885/2252/2253/5290/8823/8074/2249/2248/2247/2246/2251/5781/2263/2549/8822/8817/2254/26281/10818/2255/27006 23 Hepatitis_C_virus_genotype_1a R-HSA-5654699 SHC-mediated cascade:FGFR2 23/6120 23/10654 2.8499385782622405e-6 1.0071211517167317e-5 3.789392015417938e-6 4893/2250/2885/2252/2253/3845/3265/8823/8074/2249/2248/2247/2246/2251/6464/2263/6654/8822/8817/2254/26281/2255/27006 23 Hepatitis_C_virus_genotype_1a R-HSA-2022090 Assembly of collagen fibrils and other multimeric structures 52/6120 61/10654 2.9172989832855554e-6 1.0283478916081583e-5 3.8692597041471575e-6 256076/84171/1280/1289/84695/1300/1290/1303/1285/1296/3655/255631/1294/3918/7373/4316/1284/1298/5339/3909/1295/1288/1292/1293/3691/1302/1291/1508/1514/1286/1287/1308/4318/1277/4322/1282/85301/1299/649/4314/667/1301/1281/1297/3914/1306/1520/50509/131873/80781/1278/977 52 Hepatitis_C_virus_genotype_1a R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 31/6120 33/10654 3.4813356236838323e-6 1.215020601335199e-5 4.571634065494142e-6 23165/348995/57122/23511/23279/23225/9972/8021/55746/3303/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/3304/81929/9631/79023/23636/53371/9688/8480 31 Hepatitis_C_virus_genotype_1a R-HSA-180746 Nuclear import of Rev protein 31/6120 33/10654 3.4813356236838323e-6 1.215020601335199e-5 4.571634065494142e-6 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/1104/3837/81929/9631/79023/23636/53371/9688/8480 31 Hepatitis_C_virus_genotype_1a R-HSA-2871809 FCERI mediated Ca+2 mobilization 31/6120 33/10654 3.4813356236838323e-6 1.215020601335199e-5 4.571634065494142e-6 5335/5530/2885/7294/4773/5336/7410/7409/3702/3710/801/805/6464/2205/4772/3937/4775/10451/2206/6850/4067/695/6654/7006/9402/5532/10768/27040/5534/808/2207 31 Hepatitis_C_virus_genotype_1a R-HSA-5654726 Negative regulation of FGFR1 signaling 31/6120 33/10654 3.4813356236838323e-6 1.215020601335199e-5 4.571634065494142e-6 2250/8569/2885/5518/2253/7314/5515/5594/8074/2260/2249/6714/2248/2247/6233/2246/2251/5781/673/7311/5595/5516/8822/10253/2254/7316/26281/10818/867/2255/27006 31 Hepatitis_C_virus_genotype_1a R-HSA-948021 Transport to the Golgi and subsequent modification 136/6120 185/10654 3.5045422175845084e-6 1.220099883159051e-5 4.590745361046374e-6 6811/23256/6711/11014/126003/2153/51807/10484/7039/5861/10381/7278/1780/9570/25834/8655/84516/832/3998/55738/7846/113457/9382/375056/9632/3630/6709/51046/79090/10652/54732/51164/58485/1294/79861/10342/4253/128637/2801/10466/2517/22872/1315/8615/11316/91949/8729/10376/1314/10540/51332/83696/51128/27095/6399/7109/9334/378/6396/79694/26286/1453/26958/140735/10959/84364/22820/84617/22796/11258/6712/1783/8703/10382/10802/93661/55860/2157/830/7277/10671/9554/11196/1639/8702/10282/6710/8775/81876/347733/51143/51693/23243/5537/9871/10383/84790/10945/8704/1075/7280/829/1778/9919/10113/51399/11070/25839/55291/122553/83548/112714/1604/1781/6484/57731/10121/2525/2804/9527/22870/64377/5265/10972/6708/4905/11320/2683/9276/287/4248/375/84342/64689/288/10427 136 Hepatitis_C_virus_genotype_1a R-HSA-381119 Unfolded Protein Response (UPR) 75/6120 94/10654 3.8462827296601235e-6 1.3357779923203876e-5 5.025995581407058e-6 5393/10525/1965/2673/23404/5526/811/3576/9570/55738/10130/3309/4801/6745/6347/11340/9820/10488/8720/9695/84699/7094/9114/58477/468/3484/22872/51726/3068/8894/7466/9451/2931/64061/8570/23016/148327/118460/1968/1200/6464/37/5073/7184/7494/118/10897/1051/84447/5611/4800/1639/10954/4189/22926/90993/51010/64764/56915/167227/22894/4000/10113/440/9709/4802/1649/2081/30827/51013/467/51360/10106/54512/7709 75 Hepatitis_C_virus_genotype_1a R-HSA-202040 G-protein activation 27/6120 28/10654 3.858418713115628e-6 1.3367003404159793e-5 5.029466006492375e-6 2788/2770/2775/4988/2782/2773/2787/10681/5443/2792/2785/2783/2784/2771/2791/2781/2786/54331/59345/51764/94235/2779/5173/55970/346562/2793/2790 27 Hepatitis_C_virus_genotype_1a R-HSA-8875878 MET promotes cell motility 37/6120 41/10654 4.592293456433566e-6 1.5870425915616e-5 5.971403256043647e-6 3675/5908/3082/1280/1289/3688/3910/1290/2885/1399/5879/255631/3918/284217/6714/2335/64759/3909/1302/85440/5747/1277/3912/4233/2889/3913/2549/85301/3915/1301/1281/3673/3914/1398/5906/50509/1278 37 Hepatitis_C_virus_genotype_1a R-HSA-1852241 Organelle biogenesis and maintenance 207/6120 296/10654 4.873932486185682e-6 1.680142454197693e-5 6.321700611538913e-6 55763/5563/79738/79867/55735/79718/7531/11190/203068/11127/54801/51807/85302/79441/53632/10381/5116/7278/3313/5048/10576/5469/22832/10989/60412/8655/83658/6010/9702/132320/1432/1387/25813/7846/7840/113457/6907/2101/11064/84902/84808/2847/10499/5518/1386/55835/3054/23332/7019/93323/814/79659/79861/10575/1454/112752/9321/23408/51422/10013/54806/5465/91147/54927/983/64784/79959/2747/5310/4208/6604/8729/10376/10540/11336/117177/57545/55902/26005/54930/54820/23322/6742/378/5600/1453/6300/801/9793/4218/133522/140735/64216/57576/805/6102/80173/84617/5442/11258/22981/8636/54903/80776/79135/3842/7532/55125/10382/6753/79809/23410/121441/7277/26146/9814/4209/23354/2553/146057/9738/1639/84303/55722/4957/50807/5566/5571/2551/7283/4580/347733/22919/27077/22994/4867/5311/6648/1069/211/10651/5577/10383/583/5347/403/84790/22948/80184/22897/5564/23373/5565/22920/5108/261734/2746/57787/7280/10806/9657/1778/23265/139322/115106/10694/22995/55559/8841/9371/10142/6608/51134/95681/200186/112714/7203/1781/80321/8766/9611/23409/79598/54205/10121/347240/84131/6950/3320/79600/10733/6256/4751/10498/80254/1385/200894/26123/808/9662/55142/8195/8648/8481/51259/55755/10891 207 Hepatitis_C_virus_genotype_1a R-HSA-1250196 SHC1 events in ERBB2 signaling 22/6120 22/10654 4.968931939010198e-6 1.680142454197693e-5 6.321700611538913e-6 4893/5578/2064/145957/9542/2885/3845/3265/1839/2065/2069/5580/6464/5782/3084/6654/10718/1956/685/1950/2066/5581 22 Hepatitis_C_virus_genotype_1a R-HSA-198753 ERK/MAPK targets 22/6120 22/10654 4.968931939010198e-6 1.680142454197693e-5 6.321700611538913e-6 9252/1848/1432/6196/5518/6197/51231/5515/1849/5594/5528/5519/5598/4208/6195/5600/1846/5595/5516/1845/4205/2002 22 Hepatitis_C_virus_genotype_1a R-HSA-392170 ADP signalling through P2Y purinoceptor 12 22/6120 22/10654 4.968931939010198e-6 1.680142454197693e-5 6.321700611538913e-6 2788/64805/2770/2782/2773/2787/10681/2792/2785/2783/2784/2771/2791/2786/54331/59345/51764/94235/55970/346562/2793/2790 22 Hepatitis_C_virus_genotype_1a R-HSA-442982 Ras activation upon Ca2+ influx through NMDA receptor 22/6120 22/10654 4.968931939010198e-6 1.680142454197693e-5 6.321700611538913e-6 4893/817/1741/1739/1740/3845/3265/5923/818/57554/2902/2906/801/4747/805/2904/816/5924/815/1742/88/808 22 Hepatitis_C_virus_genotype_1a R-HSA-5654712 FRS-mediated FGFR4 signaling 22/6120 22/10654 4.968931939010198e-6 1.680142454197693e-5 6.321700611538913e-6 4893/9965/2264/2885/2253/3845/3265/8823/8074/2249/2247/2246/2251/5781/6654/8822/8817/10817/2254/152831/26281/10818 22 Hepatitis_C_virus_genotype_1a R-HSA-5655332 Signaling by FGFR3 in disease 22/6120 22/10654 4.968931939010198e-6 1.680142454197693e-5 6.321700611538913e-6 5295/4893/2250/5335/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/6654/2549/8822/8817/2254/26281/10818/2261 22 Hepatitis_C_virus_genotype_1a R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 22/6120 22/10654 4.968931939010198e-6 1.680142454197693e-5 6.321700611538913e-6 5295/4893/2250/5335/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/6654/2549/8822/8817/2254/26281/10818/2261 22 Hepatitis_C_virus_genotype_1a R-HSA-912631 Regulation of signaling by CBL 22/6120 22/10654 4.968931939010198e-6 1.680142454197693e-5 6.321700611538913e-6 5295/5291/2534/2885/1399/7314/5290/6233/7525/7409/6850/8503/2889/4067/29760/7311/5293/7316/3055/867/1398/5296 22 Hepatitis_C_virus_genotype_1a R-HSA-400253 Circadian Clock 58/6120 70/10654 5.221844674695594e-6 1.761435643856648e-5 6.627574203088844e-6 8454/79718/5936/28999/3091/5469/1387/150094/6907/2155/5499/10499/1386/23411/7314/5054/8945/10135/1454/5465/64784/4208/6604/6233/8864/1453/5500/5187/26224/10743/1374/1407/4783/406/4209/5501/8553/2908/1390/7311/23373/6095/8841/8204/4862/6500/200186/1408/6720/7316/9611/2033/6256/10498/1385/8648/551/10891 58 Hepatitis_C_virus_genotype_1a R-HSA-375165 NCAM signaling for neurite out-growth 53/6120 63/10654 5.398226362533866e-6 1.8165869143610384e-5 6.835086262321489e-6 2674/9252/4893/6711/256076/5621/1280/1289/4684/2668/1290/2534/779/2885/6709/3845/1285/5623/3265/6900/375790/1284/5594/4902/2260/1298/6714/64096/51332/1292/1293/1291/1286/1287/6712/5747/2675/6710/775/6654/5595/5786/1282/1299/776/57731/1281/1297/6708/1385/9048/50509/131873 53 Hepatitis_C_virus_genotype_1a R-HSA-5626467 RHO GTPases activate IQGAPs 30/6120 32/10654 5.719484602668781e-6 1.9110126279059195e-5 7.190372261773673e-6 71/6249/51807/10381/7278/7846/113457/8826/5879/79861/999/10376/128239/801/4221/805/84617/10382/7277/347733/998/10788/10383/60/84790/7280/1495/1499/112714/808 30 Hepatitis_C_virus_genotype_1a R-HSA-73863 RNA Polymerase I Transcription Termination 30/6120 32/10654 5.719484602668781e-6 1.9110126279059195e-5 7.190372261773673e-6 5435/2965/64425/2967/30834/404672/2068/9533/5434/9015/79101/221830/7270/4331/9013/2966/2071/10849/6908/5440/902/9014/25885/5441/51082/7343/5437/2968/84172/1022 30 Hepatitis_C_virus_genotype_1a R-HSA-917729 Endosomal Sorting Complex Required For Transport (ESCRT) 30/6120 32/10654 5.719484602668781e-6 1.9110126279059195e-5 7.190372261773673e-6 51652/27243/55048/51271/29082/27183/92421/7314/137492/25978/51160/8027/91782/79720/51534/89853/51510/9146/6233/79643/128866/7311/93343/7251/51028/155382/7316/9525/10254/84313 30 Hepatitis_C_virus_genotype_1a R-HSA-72165 mRNA Splicing - Minor Pathway 45/6120 52/10654 5.910934620875513e-6 1.9703115402918376e-5 7.413490229989446e-6 6633/6431/4904/51639/23450/5431/5435/5433/9416/8233/23020/5439/9410/10907/10262/6432/83443/10081/5438/9343/6636/2963/6635/5434/6632/24148/5436/6637/57819/2962/6426/5432/22916/23451/5440/5430/11325/5441/10594/4686/5437/6634/6427/10992/6628 45 Hepatitis_C_virus_genotype_1a R-HSA-167172 Transcription of the HIV genome 60/6120 73/10654 6.0391117115959564e-6 2.0082895078656364e-5 7.556386054231286e-6 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/11198/904/51497/2959/404672/5438/83860/2068/1025/6883/6829/2957/25920/2963/5434/5436/6878/4331/8148/2966/2962/54457/8812/2071/6880/6908/6882/2961/5432/22916/6877/6917/5440/902/5430/6749/5441/4686/6872/6879/2958/5437/6827/2968/138474/1022/8178 60 Hepatitis_C_virus_genotype_1a R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress 26/6120 27/10654 6.4992420335854385e-6 2.1546427977012177e-5 8.107054647565612e-6 5393/23404/3576/4801/6347/11340/468/3484/8570/23016/118460/5073/1051/4800/22926/51010/56915/167227/22894/440/9709/4802/1649/51013/467/54512 26 Hepatitis_C_virus_genotype_1a R-HSA-351202 Metabolism of polyamines 50/6120 59/10654 6.50977185688453e-6 2.1546427977012177e-5 8.107054647565612e-6 5689/5682/143471/5705/5709/5695/5711/4946/5683/5699/5702/5696/5691/5718/1728/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6303/5706/4947/5714/5688/5687/5708/4953/5704/5694/5684/5720/5690/51686/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 50 Hepatitis_C_virus_genotype_1a R-HSA-73893 DNA Damage Bypass 42/6120 48/10654 6.611528642779428e-6 2.183197982744495e-5 8.214496329251405e-6 56852/5982/9978/25898/57599/6117/10714/55666/7314/51514/6118/9636/11201/51455/5985/5984/6233/5424/8451/124739/7706/8450/5111/6119/83932/5427/1642/5429/9246/51426/7311/7318/5983/7320/7316/5426/9100/10459/7415/7398/5981/5980 42 Hepatitis_C_virus_genotype_1a R-HSA-176033 Interactions of Vpr with host cellular proteins 33/6120 36/10654 6.849460573046761e-6 2.2532449276806686e-5 8.478054823076201e-6 23165/348995/57122/23511/292/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/293/4927/8086/81929/9631/3159/79023/23636/53371/9688/8815/8480/291 33 Hepatitis_C_virus_genotype_1a R-HSA-3000178 ECM proteoglycans 62/6120 76/10654 6.855617545922034e-6 2.2532449276806686e-5 8.478054823076201e-6 7042/256076/54829/1280/1289/7448/4684/3688/176/3693/3910/1290/1605/3690/3694/7040/1285/7043/63827/5054/633/6678/375790/1284/284217/1298/4148/2335/3909/1288/3685/1292/1293/1291/1286/1287/351/3674/1277/3912/5802/3913/4060/2331/3371/1282/1299/3339/1634/3915/1462/1281/1297/3673/1758/4593/8516/50509/3687/3680/131873/1278 62 Hepatitis_C_virus_genotype_1a R-HSA-69231 Cyclin D associated events in G1 39/6120 44/10654 7.115871199728336e-6 2.3279300212568335e-5 8.759064805624819e-6 8454/5925/1869/5753/1031/3717/5520/1032/1030/5518/7314/5515/25/7027/5934/6714/5519/6502/595/896/6233/1163/1019/1029/4331/4067/1874/7311/5516/894/902/1027/6500/7316/1026/5933/1021/1022/1028 39 Hepatitis_C_virus_genotype_1a R-HSA-69236 G1 Phase 39/6120 44/10654 7.115871199728336e-6 2.3279300212568335e-5 8.759064805624819e-6 8454/5925/1869/5753/1031/3717/5520/1032/1030/5518/7314/5515/25/7027/5934/6714/5519/6502/595/896/6233/1163/1019/1029/4331/4067/1874/7311/5516/894/902/1027/6500/7316/1026/5933/1021/1022/1028 39 Hepatitis_C_virus_genotype_1a R-HSA-112040 G-protein mediated events 47/6120 55/10654 7.723016028517356e-6 2.520706620418859e-5 9.484405649056403e-6 5331/2770/817/5578/5582/2775/107/814/2773/818/5567/5594/112/5573/111/5613/2771/5332/5580/3710/196883/115/801/805/3838/2781/5568/113/10645/5566/84254/23236/816/5577/109/815/5321/5575/114/5330/108/2779/10768/346562/5576/1385/808 47 Hepatitis_C_virus_genotype_1a R-HSA-6790901 rRNA modification in the nucleus and cytosol 52/6120 62/10654 7.972701599868447e-6 2.5961915140449217e-5 9.768424957660624e-6 55226/10528/84135/27340/88745/51096/55272/51077/23160/10607/11103/6208/22984/10813/9136/6203/54433/27292/56902/51602/9724/54555/10171/5822/2091/55651/55127/8602/6194/10436/9277/84128/4839/134430/92856/65083/11056/9790/55505/51202/57647/6187/79050/55813/25879/57050/1736/10199/25926/27341/6201/10885 52 Hepatitis_C_virus_genotype_1a R-HSA-111931 PKA-mediated phosphorylation of CREB 21/6120 21/10654 8.662838712493095e-6 2.795103566273516e-5 1.0516851044433387e-5 107/5567/112/5573/111/5613/196883/115/801/805/5568/113/5566/5577/109/5575/114/108/5576/1385/808 21 Hepatitis_C_virus_genotype_1a R-HSA-389513 CTLA4 inhibitory signaling 21/6120 21/10654 8.662838712493095e-6 2.795103566273516e-5 1.0516851044433387e-5 5526/941/2534/5518/5515/5528/6714/5519/10000/7525/3932/5781/1493/4067/5529/208/5516/5525/207/942/5527 21 Hepatitis_C_virus_genotype_1a R-HSA-445144 Signal transduction by L1 21/6120 21/10654 8.662838712493095e-6 2.795103566273516e-5 1.0516851044433387e-5 1459/1460/8829/4684/3688/1457/5605/3690/5879/5594/2260/7410/3685/3674/3678/3897/1956/5058/5595/5604/3680 21 Hepatitis_C_virus_genotype_1a R-HSA-5621575 CD209 (DC-SIGN) signaling 21/6120 21/10654 8.662838712493095e-6 2.795103566273516e-5 1.0516851044433387e-5 9252/4893/4790/1387/2534/3385/5894/3845/3265/5062/5567/5970/5568/3384/5566/4067/5063/30835/5971/5058/2033 21 Hepatitis_C_virus_genotype_1a R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 29/6120 31/10654 9.37861566511399e-6 3.0122660792279558e-5 1.1333946277946173e-5 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/3837/81929/9631/79023/23636/53371/9688/8480 29 Hepatitis_C_virus_genotype_1a R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 29/6120 31/10654 9.37861566511399e-6 3.0122660792279558e-5 1.1333946277946173e-5 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/81929/9631/79023/23636/53371/9688/8480 29 Hepatitis_C_virus_genotype_1a R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 54/6120 65/10654 9.489133434333691e-6 3.040835941456933e-5 1.1441443183981293e-5 3725/4436/5892/472/5431/5435/5433/2965/5439/672/2967/1386/11198/904/51497/2176/404672/5438/1643/9656/2177/2068/7157/1025/2353/6829/25920/2963/5434/5436/4292/4331/2966/2962/8812/1111/2071/55215/5432/6917/5440/8621/902/5430/6749/545/5441/5395/5437/51755/6827/2968/1022/8178 54 Hepatitis_C_virus_genotype_1a R-HSA-5617833 Cilium Assembly 145/6120 201/10654 9.655573916998813e-6 3.087156286387376e-5 1.1615728020449699e-5 55763/79738/79867/7531/11190/203068/11127/54801/51807/85302/79441/10381/5116/7278/5048/10576/22832/60412/8655/83658/6010/9702/132320/7846/7840/113457/11064/84902/2847/5518/55835/23332/93323/79659/79861/10575/1454/112752/9321/10013/54806/91147/983/79959/5310/8729/10376/10540/11336/117177/57545/26005/54930/54820/23322/378/1453/9793/4218/140735/57576/6102/80173/84617/11258/22981/8636/54903/80776/3842/7532/55125/10382/6753/79809/121441/7277/26146/9814/23354/146057/9738/1639/55722/4957/50807/5566/7283/347733/22919/27077/22994/4867/5311/1069/5577/10383/583/5347/403/84790/22948/80184/22897/22920/5108/261734/57787/7280/10806/9657/1778/23265/115106/10694/22995/55559/9371/10142/6608/51134/95681/112714/7203/1781/80321/8766/79598/10121/347240/84131/6950/3320/79600/10733/4751/80254/200894/26123/9662/55142/8195/8481/51259/55755 145 Hepatitis_C_virus_genotype_1a R-HSA-180024 DARPP-32 events 25/6120 26/10654 1.0933142104028436e-5 3.459638082425373e-5 1.3017227275419097e-5 5530/5499/5518/5143/5515/84152/5567/5573/5528/5519/801/805/5568/5566/5577/1020/5141/5516/5533/5575/5532/5576/5534/5144/808 25 Hepatitis_C_virus_genotype_1a R-HSA-2173788 Downregulation of TGF-beta receptor signaling 25/6120 26/10654 1.0933142104028436e-5 3.459638082425373e-5 1.3017227275419097e-5 25805/9372/23327/4088/5499/9110/7040/7314/4092/11171/7046/9958/6233/7514/5500/5501/23645/4087/7048/7311/57154/51377/10273/64750/7316 25 Hepatitis_C_virus_genotype_1a R-HSA-6803529 FGFR2 alternative splicing 25/6120 26/10654 1.0933142104028436e-5 3.459638082425373e-5 1.3017227275419097e-5 54845/5431/5435/5433/5439/7072/7073/5438/3185/4670/5725/2963/5434/5436/2962/5432/22916/5440/23543/5430/3178/5441/4686/5437/3187 25 Hepatitis_C_virus_genotype_1a R-HSA-114604 GPVI-mediated activation cascade 32/6120 35/10654 1.0992325254798349e-5 3.459638082425373e-5 1.3017227275419097e-5 5295/5777/5291/388/2534/51206/5879/5290/5336/146850/5880/5294/7410/7409/3932/5781/5170/5590/3937/10451/1277/6850/8503/4067/998/387/27040/23533/391/5296/1278/2207 32 Hepatitis_C_virus_genotype_1a R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 32/6120 35/10654 1.0992325254798349e-5 3.459638082425373e-5 1.3017227275419097e-5 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10482/8086/22916/81929/9631/79023/23636/4686/53371/9688/10189/8480 32 Hepatitis_C_virus_genotype_1a R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 32/6120 35/10654 1.0992325254798349e-5 3.459638082425373e-5 1.3017227275419097e-5 23165/91754/348995/57122/23511/23279/23225/9972/8021/55746/10762/983/79902/9883/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/81929/9631/140609/79023/23636/53371/9688/8480 32 Hepatitis_C_virus_genotype_1a R-HSA-9615710 Microautophagy 32/6120 35/10654 1.0992325254798349e-5 3.459638082425373e-5 1.3017227275419097e-5 51652/27243/5116/55048/51271/3043/29082/3312/11315/92421/7314/137492/25978/51160/10013/91782/79720/89853/123/6233/79643/1068/128866/7311/93343/7251/155382/1080/7316/10226/200894/7431 32 Hepatitis_C_virus_genotype_1a R-HSA-1433557 Signaling by SCF-KIT 38/6120 43/10654 1.1056067173154411e-5 3.471949824977221e-5 1.3063551413128178e-5 5295/5777/4893/5578/6776/3717/2534/2885/9846/3845/3265/5879/5290/3815/9306/6714/7525/7409/3932/6777/5781/10019/2241/4318/6774/6772/8651/8503/4067/1111/6654/7006/9402/867/4254/5296/10076/2242 38 Hepatitis_C_virus_genotype_1a R-HSA-73894 DNA Repair 229/6120 334/10654 1.4583627888112098e-5 4.569536738275124e-5 1.7193329720721632e-5 2237/4436/221120/83990/151987/4350/5892/9156/2074/1763/7486/4913/56852/10445/5982/8505/11200/472/6613/27434/80198/3981/5431/5435/9978/5433/85015/26277/10980/64421/4683/2965/25898/165918/84126/5439/10987/8900/8924/57599/2067/672/2967/6612/6117/7334/10973/10714/55666/54386/348654/83695/7314/51514/7014/6118/2176/25/5888/322/328/83444/51588/7518/51720/63967/404672/9557/5531/9636/3150/23583/86/5438/3978/11201/116028/2070/890/1643/7517/9656/84464/51455/2177/5985/10920/29089/2068/7157/5984/4595/4255/6233/7158/6047/93973/55247/8607/7874/5884/5810/5424/2188/5886/57697/8451/8554/10450/8467/80010/124739/3838/5434/5436/2956/7515/7013/4292/7706/580/11073/5591/8450/4331/641/5111/2966/6119/83932/3364/22976/10524/5427/144715/1161/5889/1642/5429/142/1111/2071/55215/10721/1069/7329/9246/79728/51426/2873/146956/7311/7318/4968/23030/3980/60/5536/8533/5983/2175/2547/79840/5432/51138/7528/9318/1017/54962/25913/6917/5440/5893/2178/902/84164/5883/27339/5430/10111/7320/7520/675/51548/545/5441/7336/2072/29086/54778/7316/6996/64708/8314/79008/5426/9100/10635/10459/7415/5395/283899/7341/4798/5437/10401/65057/2033/8914/7398/2968/5932/9025/2189/79184/56949/7156/5890/5887/9716/5599/5981/57461/1022/2139/8178/50813/5980/7508 229 Hepatitis_C_virus_genotype_1a R-HSA-1474290 Collagen formation 71/6120 90/10654 1.4642713875900562e-5 4.5778772871440784e-5 1.72247118530841e-5 871/169044/256076/84171/1280/1289/84695/1300/1290/1303/1285/1296/3655/255631/1294/3918/7373/4316/1284/1305/1307/1298/5339/84570/5033/3909/1295/1288/1292/1293/57642/3691/1302/1291/1508/1514/1310/1286/1287/1308/5352/91522/4318/1277/4322/81578/340267/5479/1282/85301/10491/283208/1299/8974/136227/79709/649/4314/667/1301/1281/1297/3914/1306/1520/50509/131873/80781/1278/977/5034 71 Hepatitis_C_virus_genotype_1a R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 20/6120 20/10654 1.5101742109614989e-5 4.599018655411908e-5 1.7304258322714462e-5 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Hepatitis_C_virus_genotype_1a R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 20/6120 20/10654 1.5101742109614989e-5 4.599018655411908e-5 1.7304258322714462e-5 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Hepatitis_C_virus_genotype_1a R-HSA-167044 Signalling to RAS 20/6120 20/10654 1.5101742109614989e-5 4.599018655411908e-5 1.7304258322714462e-5 4893/5898/1432/5603/2885/3845/3265/5899/9261/6714/4914/5600/6300/6464/7867/6654/5900/25759/53358/4803 20 Hepatitis_C_virus_genotype_1a R-HSA-2028269 Signaling by Hippo 20/6120 20/10654 1.5101742109614989e-5 4.599018655411908e-5 1.7304258322714462e-5 154810/7531/60485/10413/26524/836/9414/9113/23286/1856/7082/55233/154796/6789/51421/261734/6788/7529/25937/92597 20 Hepatitis_C_virus_genotype_1a R-HSA-418217 G beta:gamma signalling through PLC beta 20/6120 20/10654 1.5101742109614989e-5 4.599018655411908e-5 1.7304258322714462e-5 2788/5331/2782/2787/10681/2792/2785/2783/2784/2791/23236/2786/54331/59345/51764/94235/5330/55970/2793/2790 20 Hepatitis_C_virus_genotype_1a R-HSA-5213460 RIPK1-mediated regulated necrosis 20/6120 20/10654 1.5101742109614989e-5 4.599018655411908e-5 1.7304258322714462e-5 356/7314/11035/8737/841/8797/6233/8772/331/8717/8743/330/8837/197259/7311/8795/7186/355/7316/329 20 Hepatitis_C_virus_genotype_1a R-HSA-5218859 Regulated Necrosis 20/6120 20/10654 1.5101742109614989e-5 4.599018655411908e-5 1.7304258322714462e-5 356/7314/11035/8737/841/8797/6233/8772/331/8717/8743/330/8837/197259/7311/8795/7186/355/7316/329 20 Hepatitis_C_virus_genotype_1a R-HSA-5654706 FRS-mediated FGFR3 signaling 20/6120 20/10654 1.5101742109614989e-5 4.599018655411908e-5 1.7304258322714462e-5 4893/2250/2885/2253/3845/3265/8823/8074/2249/2247/2246/5781/6654/8822/8817/10817/2254/26281/10818/2261 20 Hepatitis_C_virus_genotype_1a R-HSA-5654719 SHC-mediated cascade:FGFR4 20/6120 20/10654 1.5101742109614989e-5 4.599018655411908e-5 1.7304258322714462e-5 4893/9965/2264/2885/2253/3845/3265/8823/8074/2249/2247/2246/2251/6464/6654/8822/8817/2254/152831/26281 20 Hepatitis_C_virus_genotype_1a R-HSA-5654720 PI-3K cascade:FGFR4 20/6120 20/10654 1.5101742109614989e-5 4.599018655411908e-5 1.7304258322714462e-5 5295/9965/2264/2885/2253/5290/8823/8074/2249/2247/2246/2251/5781/2549/8822/8817/2254/152831/26281/10818 20 Hepatitis_C_virus_genotype_1a R-HSA-8876384 Listeria monocytogenes entry into host cells 20/6120 20/10654 1.5101742109614989e-5 4.599018655411908e-5 1.7304258322714462e-5 6456/30011/2885/7314/8027/2060/1500/6714/999/9146/6455/6233/4233/7311/79872/1499/7316/867/10254/6457 20 Hepatitis_C_virus_genotype_1a R-HSA-8964616 G beta:gamma signalling through CDC42 20/6120 20/10654 1.5101742109614989e-5 4.599018655411908e-5 1.7304258322714462e-5 2788/2782/2787/10681/2792/2785/2783/2784/2791/998/2786/5058/54331/59345/9459/51764/94235/55970/2793/2790 20 Hepatitis_C_virus_genotype_1a R-HSA-191859 snRNP Assembly 45/6120 53/10654 1.7318124006544375e-5 5.2513021181134554e-5 1.975853876468221e-5 23165/6633/6606/8487/25929/348995/57122/23511/23279/23225/79084/9972/8021/55746/10762/79902/9883/6636/10419/6396/129401/4928/6635/5903/6632/55706/7175/6637/4927/51808/8086/79833/22916/81929/11218/9631/79023/23636/4686/53371/9688/1207/6634/8480/6628 45 Hepatitis_C_virus_genotype_1a R-HSA-194441 Metabolism of non-coding RNA 45/6120 53/10654 1.7318124006544375e-5 5.2513021181134554e-5 1.975853876468221e-5 23165/6633/6606/8487/25929/348995/57122/23511/23279/23225/79084/9972/8021/55746/10762/79902/9883/6636/10419/6396/129401/4928/6635/5903/6632/55706/7175/6637/4927/51808/8086/79833/22916/81929/11218/9631/79023/23636/4686/53371/9688/1207/6634/8480/6628 45 Hepatitis_C_virus_genotype_1a R-HSA-73887 Death Receptor Signalling 105/6120 141/10654 1.7524052588968987e-5 5.3023420923704444e-5 1.9950581668941427e-5 7124/25999/4790/7531/29/356/7375/9530/8878/1894/23385/4792/8439/9138/836/23365/10616/3654/6868/26084/1540/3551/7314/5879/257397/9181/90268/81858/8737/8767/55072/23118/841/8517/8887/6453/9828/5970/5664/8797/7128/396/10454/3066/6233/7410/7409/6610/26574/8772/331/8717/8743/5663/445328/84888/56928/572/27237/7074/330/10451/27005/843/8837/8567/7189/6654/83464/7311/387/6655/55851/51107/8795/5924/1147/4804/57142/8841/7186/56957/6885/5584/10018/57580/8793/835/9459/355/23421/23370/4615/9500/7316/4168/7132/329/9099/4803/3065/55512/5599/7185/10672 105 Hepatitis_C_virus_genotype_1a R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 31/6120 34/10654 1.7598047807301246e-5 5.313329209484959e-5 1.9991921773650012e-5 7321/9140/9474/3093/64135/83737/7187/1540/7314/29110/9636/8887/7323/23586/7128/3661/51191/6233/55593/54476/7706/9246/7311/7318/5094/9641/57506/7316/7322/54941/5300 31 Hepatitis_C_virus_genotype_1a R-HSA-111465 Apoptotic cleavage of cellular proteins 34/6120 38/10654 1.8000598439139955e-5 5.3887141824176935e-5 2.027556512085493e-5 2339/660/836/324/9414/4001/6709/6093/840/2934/22985/63967/841/100506658/7082/5339/28988/10134/999/5588/5580/839/1828/5747/118/1829/8428/1832/4000/1499/329/4137/7431/6304 34 Hepatitis_C_virus_genotype_1a R-HSA-111996 Ca-dependent events 34/6120 38/10654 1.8000598439139955e-5 5.3887141824176935e-5 2.027556512085493e-5 817/5578/5582/107/814/818/5567/5594/112/5573/111/5613/5580/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5321/5575/114/108/5576/1385/808 34 Hepatitis_C_virus_genotype_1a R-HSA-5689896 Ovarian tumor domain proteases 34/6120 38/10654 1.8000598439139955e-5 5.3887141824176935e-5 2.027556512085493e-5 7321/55432/324/64135/7187/7314/8737/8767/55611/8517/80124/983/2099/23586/7128/7157/6233/55593/10318/7706/79155/79589/64127/7189/7311/387/56957/10392/57506/7316/7415/5728/78990/54764 34 Hepatitis_C_virus_genotype_1a R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 34/6120 38/10654 1.8000598439139955e-5 5.3887141824176935e-5 2.027556512085493e-5 1912/1459/6045/80012/1460/28996/1457/1911/6603/10138/57332/57492/100532731/86/865/51412/84733/6604/8289/6602/23429/55193/6015/6595/6597/8535/6599/648/6601/23466/6598/2033/6605/861 34 Hepatitis_C_virus_genotype_1a R-HSA-1643713 Signaling by EGFR in Cancer 24/6120 25/10654 1.8366056806713057e-5 5.4633206956678076e-5 2.0556279437227143e-5 5295/4893/5335/7039/2885/3845/3265/7314/1839/5290/2069/6233/255324/6464/6654/7311/1956/2549/11140/685/7316/1950/867/3320 24 Hepatitis_C_virus_genotype_1a R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 24/6120 25/10654 1.8366056806713057e-5 5.4633206956678076e-5 2.0556279437227143e-5 51807/10381/7278/10576/7846/113457/10574/10693/79861/10575/10376/84617/10382/7277/347733/10383/84790/22948/7280/10694/112714/7203/908/6950 24 Hepatitis_C_virus_genotype_1a R-HSA-9006115 Signaling by NTRK2 (TRKB) 24/6120 25/10654 1.8366056806713057e-5 5.4633206956678076e-5 2.0556279437227143e-5 5295/627/4893/5335/2534/2885/3845/3265/5879/5290/6714/4909/5781/4908/6464/2904/7074/6654/2549/1020/4915/10817/10818/8851 24 Hepatitis_C_virus_genotype_1a R-HSA-373760 L1CAM interactions 90/6120 119/10654 2.4765209690905526e-5 7.351356981931956e-5 2.766020096225238e-5 9252/6711/71/7430/1459/51807/1785/1460/10381/7278/8829/4684/3688/1457/285643/5605/7846/113457/3690/1808/6456/1741/1739/6709/5962/163/6196/1759/6197/8986/3312/100133941/5879/6900/161/79861/5594/284217/2260/3672/8650/6714/10376/6195/214/7410/51332/3685/1213/1211/1175/1173/84617/6712/3674/10382/7277/3678/4478/160/3912/26052/6710/27330/347733/6386/2048/3897/10383/24137/1956/60/84790/5058/8506/7280/5595/5604/10048/11313/112714/3915/57731/3673/6708/1742/287/3680/288/2596 90 Hepatitis_C_virus_genotype_1a R-HSA-72086 mRNA Capping 27/6120 29/10654 2.5061550880365968e-5 7.392633209480338e-5 2.781550681282636e-5 5431/5435/5433/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/4686/5437/2968/1022 27 Hepatitis_C_virus_genotype_1a R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 27/6120 29/10654 2.5061550880365968e-5 7.392633209480338e-5 2.781550681282636e-5 2308/84676/4089/4088/3630/56729/2538/847/3484/5443/3066/2645/5105/4303/23410/4287/2908/4852/6648/4087/25942/2309/6720/114907/3065/91584/10891 27 Hepatitis_C_virus_genotype_1a R-HSA-9619483 Activation of AMPK downstream of NMDARs 27/6120 29/10654 2.5061550880365968e-5 7.392633209480338e-5 2.781550681282636e-5 5563/51807/53632/10381/7278/7846/113457/79861/51422/10376/801/805/84617/10382/7277/10645/5571/347733/5562/10383/84790/5564/5565/7280/112714/4137/808 27 Hepatitis_C_virus_genotype_1a R-HSA-2980766 Nuclear Envelope Breakdown 44/6120 52/10654 2.5815316099950783e-5 7.599080522114949e-5 2.8592285055214147e-5 23165/5579/91754/5578/348995/57122/23511/23279/23225/4001/9972/8021/55746/10762/983/79902/9883/7444/2010/23175/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/5347/7112/4000/81929/9631/140609/79023/23636/7443/53371/9688/8815/23592/8480 44 Hepatitis_C_virus_genotype_1a R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 19/6120 19/10654 2.6324705349246933e-5 7.62173193889901e-5 2.8677513230347896e-5 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Hepatitis_C_virus_genotype_1a R-HSA-163615 PKA activation 19/6120 19/10654 2.6324705349246933e-5 7.62173193889901e-5 2.8677513230347896e-5 107/5567/112/5573/111/196883/115/801/805/5568/113/5566/5577/109/5575/114/108/5576/808 19 Hepatitis_C_virus_genotype_1a R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 19/6120 19/10654 2.6324705349246933e-5 7.62173193889901e-5 2.8677513230347896e-5 11065/7321/8697/51529/29945/51434/29882/996/51433/119504/7324/64682/246184/8881/10393/51343/25906/991/8556 19 Hepatitis_C_virus_genotype_1a R-HSA-176412 Phosphorylation of the APC/C 19/6120 19/10654 2.6324705349246933e-5 7.62173193889901e-5 2.8677513230347896e-5 11065/7321/8697/51529/29945/51434/29882/996/983/51433/119504/7324/64682/246184/8881/891/10393/25906/5347 19 Hepatitis_C_virus_genotype_1a R-HSA-392851 Prostacyclin signalling through prostacyclin receptor 19/6120 19/10654 2.6324705349246933e-5 7.62173193889901e-5 2.8677513230347896e-5 2788/2782/2787/10681/2792/2785/2783/2784/2791/2786/54331/59345/51764/94235/55970/2778/2793/5739/2790 19 Hepatitis_C_virus_genotype_1a R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 19/6120 19/10654 2.6324705349246933e-5 7.62173193889901e-5 2.8677513230347896e-5 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Hepatitis_C_virus_genotype_1a R-HSA-77595 Processing of Intronless Pre-mRNAs 19/6120 19/10654 2.6324705349246933e-5 7.62173193889901e-5 2.8677513230347896e-5 51585/81608/1477/53981/11051/8106/1478/23283/10914/10898/51692/22916/1479/79869/29894/4686/8189/10978/55339 19 Hepatitis_C_virus_genotype_1a R-HSA-8851708 Signaling by FGFR2 IIIa TM 19/6120 19/10654 2.6324705349246933e-5 7.62173193889901e-5 2.8677513230347896e-5 5431/5435/5433/5439/5438/2247/2246/2963/5434/5436/2263/2962/5432/22916/5440/5430/5441/4686/5437 19 Hepatitis_C_virus_genotype_1a R-HSA-113418 Formation of the Early Elongation Complex 30/6120 33/10654 2.8100974392518076e-5 8.053328027124082e-5 3.0301435801945045e-5 5431/5435/5433/2965/5439/2967/51497/404672/5438/2068/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/4686/5437/6827/2968/1022 30 Hepatitis_C_virus_genotype_1a R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 30/6120 33/10654 2.8100974392518076e-5 8.053328027124082e-5 3.0301435801945045e-5 5431/5435/5433/2965/5439/2967/51497/404672/5438/2068/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/4686/5437/6827/2968/1022 30 Hepatitis_C_virus_genotype_1a R-HSA-180910 Vpr-mediated nuclear import of PICs 30/6120 33/10654 2.8100974392518076e-5 8.053328027124082e-5 3.0301435801945045e-5 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/3159/79023/23636/53371/9688/8815/8480 30 Hepatitis_C_virus_genotype_1a R-HSA-389356 CD28 co-stimulation 30/6120 33/10654 2.8100974392518076e-5 8.053328027124082e-5 3.0301435801945045e-5 5295/941/2534/2885/2475/5062/5879/1326/5290/9020/6714/10000/7525/7409/3932/940/253260/5170/64223/8503/4067/5063/998/208/79109/5058/9402/207/942/5296 30 Hepatitis_C_virus_genotype_1a R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 30/6120 33/10654 2.8100974392518076e-5 8.053328027124082e-5 3.0301435801945045e-5 4790/4792/177/3654/7334/3551/7314/257397/6283/8767/23118/8517/5970/10454/6233/4791/351/64127/3656/7189/7311/1147/6885/10392/7316/7335/4793/3146/6288/6285 30 Hepatitis_C_virus_genotype_1a R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 33/6120 37/10654 2.822785967292742e-5 8.073282381100947e-5 3.0376516013996847e-5 79718/27327/346/9612/64240/6907/192669/4343/1071/9619/10062/344/5360/64241/348/6257/26523/341/19/10123/27161/8841/347/57690/192670/9611/2874/2033/23028/6256/23112/7376/8648 33 Hepatitis_C_virus_genotype_1a R-HSA-450302 activated TAK1 mediates p38 MAPK activation 23/6120 24/10654 3.0805661917397094e-5 8.75725469829232e-5 3.2950028875993496e-5 1432/3654/7334/7314/257397/5606/8767/23118/8517/9261/10454/6233/5600/5608/7867/64127/3656/7189/7311/6885/10392/7316/7335 23 Hepatitis_C_virus_genotype_1a R-HSA-5627123 RHO GTPases activate PAKs 23/6120 24/10654 3.0805661917397094e-5 8.75725469829232e-5 3.2950028875993496e-5 2017/79784/4628/5062/5879/4638/4659/4771/801/5500/805/2316/10627/5063/998/5058/4660/3984/4627/10398/4637/103910/808 23 Hepatitis_C_virus_genotype_1a R-HSA-982772 Growth hormone receptor signaling 23/6120 24/10654 3.0805661917397094e-5 8.75725469829232e-5 3.2950028875993496e-5 5777/5770/9021/6776/3717/5618/6868/8660/1154/3667/2690/5594/5617/8835/6777/6774/6772/8651/1442/4067/2689/5595/2688 23 Hepatitis_C_virus_genotype_1a R-HSA-8856688 Golgi-to-ER retrograde transport 99/6120 133/10654 3.119768356303175e-5 8.850851876031141e-5 3.330219742829186e-5 11014/64837/11127/51807/53407/5861/10381/7278/1780/5048/8655/84516/832/285643/55738/10112/636/7846/113457/11004/81930/54732/51164/60561/79861/29127/23299/1315/3796/5870/11316/55614/56992/8729/10376/1314/10540/3835/3833/378/9493/26286/26958/140735/10959/3831/84364/22820/84617/11258/1783/55850/9585/10382/93661/55860/830/3832/7277/10671/9554/23303/1639/8775/81876/9183/1062/146909/347733/662/51143/10383/24137/84790/84643/10945/5049/22920/7280/829/22931/1778/55582/5321/9371/23095/5050/112714/1781/22930/25782/10121/6836/51560/10972/4905/9276/3799/375 99 Hepatitis_C_virus_genotype_1a R-HSA-74752 Signaling by Insulin receptor 62/6120 78/10654 3.320531423449622e-5 9.40150463265857e-5 3.537408238043986e-5 5295/3643/4893/2250/5291/10312/9965/2264/3630/2885/8660/9846/2252/2253/3845/3265/2323/54106/5290/3667/8823/526/537/9550/9114/5594/8074/2260/2249/2248/2247/529/2246/2251/523/528/5781/30849/5170/6464/2322/5140/527/2263/208/6654/2549/5595/8822/8817/2254/152831/5289/26281/10818/2261/245972/2255/27006/5296/51382/9296 62 Hepatitis_C_virus_genotype_1a R-HSA-5689880 Ub-specific processing proteases 155/6120 220/10654 3.990370509371334e-5 1.1275395627682527e-4 4.242478086115711e-5 5689/5682/79594/7419/10474/7375/9817/91833/6478/3091/143471/5705/11274/55031/8239/5709/5695/4792/9986/11047/4609/4194/4089/5711/4088/5683/408/64135/5699/8724/8312/5702/8900/8975/57599/377630/6881/51616/1540/80351/100287404/5696/5691/7314/5718/90865/2648/5700/122706/5707/8737/55611/57646/23198/63967/9101/8517/993/890/7417/4092/1643/9861/23586/81847/7046/6502/5698/9146/5692/5713/5710/10454/219333/7157/10869/9958/8313/5719/6233/100287478/9804/23770/8607/7874/10600/23326/51651/93624/8237/4303/409/330/5706/27005/7416/25862/9738/8658/84132/5714/79589/55288/5688/9097/5687/5708/4087/63891/84749/7189/5704/7311/367/29761/5694/9960/23358/23032/5684/8295/5720/7186/6885/991/5690/2625/5717/9491/4086/1080/57695/10197/64750/7316/10213/8678/9100/5715/3416/5701/329/9099/5685/5686/5728/10868/5716/9736/5693/154/10254/5721/100287205/4193 155 Hepatitis_C_virus_genotype_1a R-HSA-350054 Notch-HLH transcription pathway 26/6120 28/10654 4.082994519969281e-5 1.1491062421470432e-4 4.3236248304748776e-5 79718/9759/9612/22938/1387/6907/4853/9794/2648/9734/55869/51564/55534/84441/10013/4854/8850/3066/10046/10014/4855/4851/8841/9611/3065/3516 26 Hepatitis_C_virus_genotype_1a R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 26/6120 28/10654 4.082994519969281e-5 1.1491062421470432e-4 4.3236248304748776e-5 2788/2770/2782/2787/10681/112/111/2792/2785/2783/2784/2771/2791/9254/150/775/2786/54331/59345/776/51764/94235/55970/152/2793/2790 26 Hepatitis_C_virus_genotype_1a R-HSA-111933 Calmodulin induced events 32/6120 36/10654 4.413524270881114e-5 1.23719070018735e-4 4.655051234747477e-5 817/5578/5582/107/814/818/5567/112/5573/111/5613/5580/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5575/114/108/5576/1385/808 32 Hepatitis_C_virus_genotype_1a R-HSA-111997 CaM pathway 32/6120 36/10654 4.413524270881114e-5 1.23719070018735e-4 4.655051234747477e-5 817/5578/5582/107/814/818/5567/112/5573/111/5613/5580/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5575/114/108/5576/1385/808 32 Hepatitis_C_virus_genotype_1a R-HSA-5654221 Phospholipase C-mediated cascade; FGFR2 18/6120 18/10654 4.588488464349236e-5 1.2685821048494947e-4 4.7731644706543144e-5 2250/5335/2252/2253/8823/8074/2249/2248/2247/2246/2251/2263/8822/8817/2254/26281/2255/27006 18 Hepatitis_C_virus_genotype_1a R-HSA-5654704 SHC-mediated cascade:FGFR3 18/6120 18/10654 4.588488464349236e-5 1.2685821048494947e-4 4.7731644706543144e-5 4893/2250/2885/2253/3845/3265/8823/8074/2249/2247/2246/6464/6654/8822/8817/2254/26281/2261 18 Hepatitis_C_virus_genotype_1a R-HSA-5654710 PI-3K cascade:FGFR3 18/6120 18/10654 4.588488464349236e-5 1.2685821048494947e-4 4.7731644706543144e-5 5295/2250/2885/2253/5290/8823/8074/2249/2247/2246/5781/2549/8822/8817/2254/26281/10818/2261 18 Hepatitis_C_virus_genotype_1a R-HSA-5675482 Regulation of necroptotic cell death 18/6120 18/10654 4.588488464349236e-5 1.2685821048494947e-4 4.7731644706543144e-5 356/7314/8737/841/8797/6233/8772/331/8717/8743/330/8837/7311/8795/7186/355/7316/329 18 Hepatitis_C_virus_genotype_1a R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 18/6120 18/10654 4.588488464349236e-5 1.2685821048494947e-4 4.7731644706543144e-5 4893/5578/2885/6196/6197/3845/3265/1839/5594/5598/6195/2520/887/6654/1956/5595/4314/1385 18 Hepatitis_C_virus_genotype_1a R-HSA-8963898 Plasma lipoprotein assembly 18/6120 18/10654 4.588488464349236e-5 1.2685821048494947e-4 4.7731644706543144e-5 29801/346/344/345/5567/348/336/51128/5568/341/338/19/335/5566/4547/649/2/5034 18 Hepatitis_C_virus_genotype_1a R-HSA-8964315 G beta:gamma signalling through BTK 18/6120 18/10654 4.588488464349236e-5 1.2685821048494947e-4 4.7731644706543144e-5 2788/2782/2787/10681/2792/2785/2783/2784/2791/695/2786/54331/59345/51764/94235/55970/2793/2790 18 Hepatitis_C_virus_genotype_1a R-HSA-9024446 NR1H2 and NR1H3-mediated signaling 40/6120 47/10654 4.625010519339995e-5 1.276177070894206e-4 4.801741274585143e-5 79718/27327/346/9612/64240/6907/192669/4343/1071/27329/9619/10062/344/5360/64241/348/6257/26523/29116/5105/6319/341/19/10123/27161/8841/347/8204/57690/6720/192670/9611/2874/2194/2033/23028/6256/23112/7376/8648 40 Hepatitis_C_virus_genotype_1a R-HSA-389948 PD-1 signaling 22/6120 23/10654 5.1586785875465185e-5 1.415123892692722e-4 5.3245423062122575e-5 5777/3115/3113/3117/3127/5133/3126/29126/1445/916/3932/5781/3120/3123/80380/3122/920/3125/3119/919/915/917 22 Hepatitis_C_virus_genotype_1a R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 22/6120 23/10654 5.1586785875465185e-5 1.415123892692722e-4 5.3245423062122575e-5 3654/7334/7314/257397/5601/8767/23118/8517/10454/6233/64127/5602/3656/7189/7311/6416/6885/10392/7316/7335/5609/5599 22 Hepatitis_C_virus_genotype_1a R-HSA-5654693 FRS-mediated FGFR1 signaling 22/6120 23/10654 5.1586785875465185e-5 1.415123892692722e-4 5.3245423062122575e-5 4893/2250/2885/2253/3845/3265/8074/2260/2249/2248/2247/2246/2251/5781/6654/8822/10817/2254/26281/10818/2255/27006 22 Hepatitis_C_virus_genotype_1a R-HSA-1650814 Collagen biosynthesis and modifying enzymes 54/6120 67/10654 5.232976797401315e-5 1.4327179192885156e-4 5.3907415552177064e-5 871/169044/256076/1280/1289/1300/1290/1303/1285/1296/255631/1294/7373/1284/1305/1307/1298/84570/5033/1295/1288/1292/1293/57642/1302/1291/1310/1286/1287/1308/5352/91522/1277/81578/340267/5479/1282/85301/10491/283208/1299/8974/136227/79709/649/1301/1281/1297/1306/50509/131873/80781/1278/5034 54 Hepatitis_C_virus_genotype_1a R-HSA-1632852 Macroautophagy 73/6120 95/10654 5.7388266536787494e-5 1.5681677483889606e-4 5.90038480916787e-5 51652/5563/65018/1459/27243/9140/8878/1460/53632/9474/8655/1457/29082/55054/2475/84557/3312/64121/92421/7314/139341/25978/60673/9821/51422/7249/10533/91782/192111/6714/8408/123/55669/6233/9804/30849/57521/140735/28956/7405/79643/389541/22863/7416/26100/64223/5571/128866/6009/55004/7311/5562/11345/55626/5564/5565/401505/7248/11337/10452/8897/64419/100188893/7316/11152/5289/8678/56993/10226/8649/81631/10542/23710 73 Hepatitis_C_virus_genotype_1a R-HSA-1980143 Signaling by NOTCH1 58/6120 73/10654 6.100285325755612e-5 1.6637141797515303e-4 6.259887619221885e-5 8454/79718/182/3091/23385/9978/9759/9612/4609/22938/1387/6907/408/83737/6868/9794/388585/7314/2648/9734/55869/51564/55534/3280/84441/10013/7091/8650/102/5664/8850/3066/6233/7089/5663/7090/142678/23220/409/10046/1024/10014/7088/83464/7311/55851/51107/4851/8841/23462/6500/7316/9611/2033/55294/3065/92737/3516 58 Hepatitis_C_virus_genotype_1a R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 34/6120 39/10654 6.256779676134147e-5 1.7031002593338124e-4 6.408081602868544e-5 9134/10528/10576/10574/6468/10564/54461/10693/8877/10575/898/10517/26985/26190/10238/7157/26224/2629/8237/6774/26272/26270/55135/22948/84261/10694/8841/7203/908/11328/6950/3801/55294/26234 34 Hepatitis_C_virus_genotype_1a R-HSA-1538133 G0 and Early G1 25/6120 27/10654 6.635689298456554e-5 1.7855576165694162e-4 6.718335488995789e-5 9134/1869/4609/5928/990/8900/7027/7153/898/5934/993/890/983/1859/286826/5111/91750/1874/55957/1017/4605/4149/5933/3065/132660 25 Hepatitis_C_virus_genotype_1a R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 25/6120 27/10654 6.635689298456554e-5 1.7855576165694162e-4 6.718335488995789e-5 5431/5435/5433/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/5440/902/5430/5441/5437/2968/1022 25 Hepatitis_C_virus_genotype_1a R-HSA-354192 Integrin alphaIIb beta3 signaling 25/6120 27/10654 6.635689298456554e-5 1.7855576165694162e-4 6.718335488995789e-5 5770/5908/2244/3690/2885/9564/7094/10125/6714/2335/1445/2266/2243/5170/6464/5747/3674/6850/6654/7450/207/54518/1398/10235/5906 25 Hepatitis_C_virus_genotype_1a R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 25/6120 27/10654 6.635689298456554e-5 1.7855576165694162e-4 6.718335488995789e-5 356/836/929/26060/219699/1612/8737/841/8797/1613/8772/8717/8743/8837/8795/23643/7186/842/355/7099/9500/23604/1630/353376/148022 25 Hepatitis_C_virus_genotype_1a R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 25/6120 27/10654 6.635689298456554e-5 1.7855576165694162e-4 6.718335488995789e-5 5431/5435/5433/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/5440/902/5430/5441/5437/2968/1022 25 Hepatitis_C_virus_genotype_1a R-HSA-9006921 Integrin signaling 25/6120 27/10654 6.635689298456554e-5 1.7855576165694162e-4 6.718335488995789e-5 5770/5908/2244/3690/2885/9564/7094/10125/6714/2335/1445/2266/2243/5170/6464/5747/3674/6850/6654/7450/207/54518/1398/10235/5906 25 Hepatitis_C_virus_genotype_1a R-HSA-9006931 Signaling by Nuclear Receptors 204/6120 299/10654 6.718821677528645e-5 1.80448353625055e-4 6.789546116239473e-5 5295/2788/5161/3725/4893/857/7764/79718/7031/5160/2770/10901/7039/27327/10274/5915/346/8644/5431/5435/5433/1509/5469/1105/9612/4609/64240/124/1387/6907/8312/2782/5439/192669/10499/1386/5914/4343/3845/904/1071/3265/27329/8877/216/9619/2773/10062/2787/6387/1839/5290/4316/344/5360/64241/5594/2069/10681/1737/5481/5438/348/4313/865/1655/6667/2792/6714/2099/2494/8850/5467/10000/5162/2785/595/2783/2784/2771/7514/1025/2353/6257/255324/5164/26523/801/29116/2791/2957/805/5105/5170/2963/3838/5434/5590/6464/112724/1374/7090/5241/6319/5747/5436/1903/3315/4318/126/200845/341/5885/19/57678/7033/2962/8503/10524/2171/8243/4602/2786/208/3326/23030/6908/1956/5536/3169/858/5432/3480/10728/5595/7528/3727/10123/27161/7392/596/5440/8841/685/54331/4435/347/2309/9687/59345/8204/5430/8854/207/5451/2625/57690/6722/1027/51764/94235/5441/10735/6720/192670/2100/1950/9611/55970/2874/2194/4314/127/346562/2289/7391/2958/5163/5437/2793/3320/2033/4846/9126/3065/2002/2066/861/23028/6256/23112/7376/10498/1385/1738/5296/808/6258/3276/5916/8202/8648/2288/2790 204 Hepatitis_C_virus_genotype_1a R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 28/6120 31/10654 7.105827910428752e-5 1.8975790442622234e-4 7.139827087033675e-5 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/2645/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/79023/23636/53371/9688/8480 28 Hepatitis_C_virus_genotype_1a R-HSA-182971 EGFR downregulation 28/6120 31/10654 7.105827910428752e-5 1.8975790442622234e-4 7.139827087033675e-5 7039/6456/30011/2885/10252/7314/1839/8027/2060/2069/9146/6455/6233/29924/255324/5782/5796/998/7311/1956/10253/685/58513/7316/1950/867/10254/6457 28 Hepatitis_C_virus_genotype_1a R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 28/6120 31/10654 7.105827910428752e-5 1.8975790442622234e-4 7.139827087033675e-5 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/2645/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/79023/23636/53371/9688/8480 28 Hepatitis_C_virus_genotype_1a R-HSA-382556 ABC-family proteins mediated transport 78/6120 103/10654 7.88495633831021e-5 2.0920679246025725e-4 7.871610556175413e-5 5689/1965/5682/8714/143471/91319/5705/8504/5709/5695/64240/5711/5683/5699/6400/5702/51009/4363/10057/5696/5691/9619/7314/5718/5700/122706/5707/10956/79139/91445/64241/23198/9861/8894/5698/215/5692/5713/5710/5719/10613/6233/27248/10058/1968/5243/5706/335/340273/5714/5688/5687/10347/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/5824/1244/7316/10213/7415/5715/5701/5825/5685/5686/5716/5693/5721 78 Hepatitis_C_virus_genotype_1a R-HSA-164378 PKA activation in glucagon signalling 17/6120 17/10654 7.997337669225436e-5 2.0920679246025725e-4 7.871610556175413e-5 107/5567/112/5573/111/196883/115/5568/113/5566/5577/109/5575/114/108/2778/5576 17 Hepatitis_C_virus_genotype_1a R-HSA-196299 Beta-catenin phosphorylation cascade 17/6120 17/10654 7.997337669225436e-5 2.0920679246025725e-4 7.871610556175413e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/10023/23401/5529/5516/1499/5525/139285/5527 17 Hepatitis_C_virus_genotype_1a R-HSA-2033519 Activated point mutants of FGFR2 17/6120 17/10654 7.997337669225436e-5 2.0920679246025725e-4 7.871610556175413e-5 2250/2252/2253/8823/8074/2249/2248/2247/2246/2251/2263/8822/8817/2254/26281/2255/27006 17 Hepatitis_C_virus_genotype_1a R-HSA-432142 Platelet sensitization by LDL 17/6120 17/10654 7.997337669225436e-5 2.0920679246025725e-4 7.871610556175413e-5 5777/5526/5175/2268/1432/5518/5515/5528/5519/5781/338/5529/5516/5321/5525/5527/7804 17 Hepatitis_C_virus_genotype_1a R-HSA-450604 KSRP (KHSRP) binds and destabilizes mRNA 17/6120 17/10654 7.997337669225436e-5 2.0920679246025725e-4 7.871610556175413e-5 5393/23404/1432/11340/7534/5600/8570/23016/118460/5073/51010/56915/167227/22894/207/51013/54512 17 Hepatitis_C_virus_genotype_1a R-HSA-5655862 Translesion synthesis by POLK 17/6120 17/10654 7.997337669225436e-5 2.0920679246025725e-4 7.871610556175413e-5 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/51426/7311/5983/7316/10459/5981/5980 17 Hepatitis_C_virus_genotype_1a R-HSA-5656121 Translesion synthesis by POLI 17/6120 17/10654 7.997337669225436e-5 2.0920679246025725e-4 7.871610556175413e-5 5982/6117/7314/6118/11201/51455/5985/5984/6233/5111/6119/7311/5983/7316/10459/5981/5980 17 Hepatitis_C_virus_genotype_1a R-HSA-6788467 IL-6-type cytokine receptor ligand interactions 17/6120 17/10654 7.997337669225436e-5 2.0920679246025725e-4 7.871610556175413e-5 23529/3717/133396/3572/3976/1271/7297/9180/3589/9244/386653/3716/1270/5008/3590/3977/1489 17 Hepatitis_C_virus_genotype_1a R-HSA-8934593 Regulation of RUNX1 Expression and Activity 17/6120 17/10654 7.997337669225436e-5 2.0920679246025725e-4 7.871610556175413e-5 27327/192669/5371/4343/865/6714/595/896/26523/5781/27161/894/57690/192670/1021/861/23112 17 Hepatitis_C_virus_genotype_1a R-HSA-9034015 Signaling by NTRK3 (TRKC) 17/6120 17/10654 7.997337669225436e-5 2.0920679246025725e-4 7.871610556175413e-5 5295/4893/5335/2885/3845/3265/5290/3667/6714/25920/4908/5800/6464/5802/6654/4916/581 17 Hepatitis_C_virus_genotype_1a R-HSA-1489509 DAG and IP3 signaling 36/6120 42/10654 8.246262512979226e-5 2.1492107473753623e-4 8.086616025958809e-5 5335/817/5578/5582/107/814/818/5567/112/5573/111/5613/5580/3710/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5575/114/108/10768/5576/1385/5581/808 36 Hepatitis_C_virus_genotype_1a R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 36/6120 42/10654 8.246262512979226e-5 2.1492107473753623e-4 8.086616025958809e-5 2788/2740/9495/2782/8826/2787/5567/3745/10681/112/5573/111/2792/2785/2783/2784/3710/2791/5568/5566/2641/2786/5577/54331/5575/59345/51764/94235/114/3790/55970/2778/2793/5576/5906/2790 36 Hepatitis_C_virus_genotype_1a R-HSA-202427 Phosphorylation of CD3 and TCR zeta chains 21/6120 22/10654 8.623488095563415e-5 2.235132024769194e-4 8.409903251091258e-5 5788/3115/3113/3117/55824/26191/3127/3126/1445/916/3932/3120/3123/3122/920/5795/3125/3119/919/915/917 21 Hepatitis_C_virus_genotype_1a R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 21/6120 22/10654 8.623488095563415e-5 2.235132024769194e-4 8.409903251091258e-5 3725/7531/356/7001/4001/826/823/2801/993/351/6648/1020/4000/994/2309/10018/831/824/995/8851/5052 21 Hepatitis_C_virus_genotype_1a R-HSA-8863678 Neurodegenerative Diseases 21/6120 22/10654 8.623488095563415e-5 2.235132024769194e-4 8.409903251091258e-5 3725/7531/356/7001/4001/826/823/2801/993/351/6648/1020/4000/994/2309/10018/831/824/995/8851/5052 21 Hepatitis_C_virus_genotype_1a R-HSA-194315 Signaling by Rho GTPases 300/6120 455/10654 9.48426664335372e-5 2.453727700390596e-4 9.232390899565959e-5 55839/11130/394/398/64837/71/6249/51517/5579/392/9735/7531/55789/5526/29/51807/2909/10811/10971/5578/9212/613/1894/388/7533/2810/147841/147179/348995/54509/10381/57122/6280/7278/1780/23122/3688/5048/57405/8655/10094/23279/5881/1432/2017/2491/9138/7846/113457/23365/79784/9475/1060/171177/9322/397/4628/11004/8976/1855/2885/23433/6093/9184/8826/10499/5518/26084/23332/25909/3071/10726/81930/5062/55746/9411/2665/5879/5515/9181/85415/26999/25/79682/64333/1072/10403/79861/4638/25936/4659/10093/1856/10006/4771/389/5594/29127/3619/64105/7534/94274/332/5528/6453/9828/6714/79902/3796/5519/81565/57636/999/396/10810/5880/91687/11243/10376/23002/57584/11113/58504/83540/7410/5580/7409/1857/128239/9055/23191/7514/54820/29984/1729/6396/1535/5600/801/64946/9793/30849/10109/5586/140735/9886/2664/5500/10787/4221/805/3831/220134/5170/84617/4928/4688/9743/445328/5590/114793/5903/653361/55055/5747/80776/1783/401541/2316/7532/3633/27237/10382/7074/10627/79172/7277/10451/79980/58480/6232/5501/10152/6279/55288/54821/10092/9183/4650/10163/1062/699/752/347733/22919/55845/5063/3895/57514/5529/51143/998/695/10788/354/6654/10097/57120/367/57381/10383/5347/387/6655/60/84790/84643/5058/5924/4660/93663/7280/7529/5595/1778/5516/5905/81929/3984/27035/54908/55143/1495/1499/5525/4690/1058/991/79019/57580/4627/10928/348235/80152/10458/1063/3985/6722/8379/1027/9459/1080/23421/79023/55920/23370/30851/112714/1781/9824/10398/4085/5289/5585/5216/4168/10552/81624/55166/79658/8936/4637/1123/995/79003/391/23221/23028/89941/2/1742/90627/5527/10096/7454/701/23380/9928/29941/3799/103910/57551/5296/5300/808/10095/1536/399/4952/10672 300 Hepatitis_C_virus_genotype_1a R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 33/6120 38/10654 9.57277838159247e-5 2.472091120521132e-4 9.301485067134385e-5 5908/1265/3313/6175/3936/5898/3181/4001/4282/5062/1072/6627/9049/27250/9987/3185/3458/5478/302/6775/9446/4478/998/6648/2939/3586/829/5055/6647/6950/5306/375/5721 33 Hepatitis_C_virus_genotype_1a R-HSA-383280 Nuclear Receptor transcription pathway 43/6120 52/10654 9.828963905296076e-5 2.533608611785643e-4 9.53295065576681e-5 3174/7068/5915/6097/4929/5469/9612/8856/29959/2101/7067/5914/8431/7421/10062/7025/2516/5465/2099/7101/2494/5467/2103/6257/190/5241/7182/3172/2649/9970/2908/9971/367/6095/5468/2100/4306/9611/3164/6256/7376/6258/5916 43 Hepatitis_C_virus_genotype_1a R-HSA-4791275 Signaling by WNT in cancer 30/6120 34/10654 1.0687292378164466e-4 2.7498325279583756e-4 1.034651432692065e-4 27123/5526/1452/324/8312/79412/5518/80351/5515/8322/8325/5528/89780/5519/2932/4040/7855/22943/4041/8658/6934/5529/5516/1487/1499/5525/139285/54894/5527/1488 30 Hepatitis_C_virus_genotype_1a R-HSA-3238698 WNT ligand biogenesis and trafficking 24/6120 26/10654 1.0756103323892829e-4 2.757473761216161e-4 1.0375265215774135e-4 7478/81029/55737/9559/8724/7476/79971/7473/7471/89780/51699/7477/7475/7481/7482/7474/7479/7480/80326/7483/51384/7472/7484/54361 24 Hepatitis_C_virus_genotype_1a R-HSA-912694 Regulation of IFNA signaling 24/6120 26/10654 1.0756103323892829e-4 2.757473761216161e-4 1.0375265215774135e-4 3443/5777/5770/9021/11274/3445/3444/3451/3448/3439/3452/6773/7297/5781/3446/3455/6772/8651/3440/3454/3716/3456/3441/3449 24 Hepatitis_C_virus_genotype_1a R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF) 45/6120 55/10654 1.1211106196074075e-4 2.868903763423674e-4 1.0794531517473178e-4 79718/51141/10484/3638/5469/1387/6907/4801/9632/6309/10499/31/8720/5465/3157/6667/3156/6604/51128/10654/6319/6721/10802/9453/4800/57678/32/1595/5901/9871/3837/4802/79071/6720/2194/22937/4597/1717/6256/10498/51360/2224/4520/8648/10427 45 Hepatitis_C_virus_genotype_1a R-HSA-8874081 MET activates PTK2 signaling 27/6120 30/10654 1.124869706286761e-4 2.873308488884661e-4 1.081110472861418e-4 3675/3082/1280/1289/3688/3910/1290/255631/3918/284217/6714/2335/3909/1302/5747/1277/3912/4233/3913/85301/3915/1301/1281/3673/3914/50509/1278 27 Hepatitis_C_virus_genotype_1a R-HSA-8853659 RET signaling 35/6120 41/10654 1.241331544922172e-4 3.159576753612763e-4 1.188821712445564e-4 5295/2674/5335/5291/5578/2668/2885/8660/9846/5623/5290/5567/4902/6714/5598/64096/9260/5781/6464/5568/2675/2676/5566/8503/6654/5293/2549/85358/5909/10818/53358/5979/9048/5296/9046 35 Hepatitis_C_virus_genotype_1a R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 47/6120 58/10654 1.2503856939829233e-4 3.159576753612763e-4 1.188821712445564e-4 8454/79718/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/388585/7314/2648/9734/55869/51564/55534/3280/84441/10013/102/5664/8850/3066/6233/5663/142678/10046/1024/10014/83464/7311/55851/51107/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 47 Hepatitis_C_virus_genotype_1a R-HSA-2644603 Signaling by NOTCH1 in Cancer 47/6120 58/10654 1.2503856939829233e-4 3.159576753612763e-4 1.188821712445564e-4 8454/79718/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/388585/7314/2648/9734/55869/51564/55534/3280/84441/10013/102/5664/8850/3066/6233/5663/142678/10046/1024/10014/83464/7311/55851/51107/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 47 Hepatitis_C_virus_genotype_1a R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 47/6120 58/10654 1.2503856939829233e-4 3.159576753612763e-4 1.188821712445564e-4 8454/79718/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/388585/7314/2648/9734/55869/51564/55534/3280/84441/10013/102/5664/8850/3066/6233/5663/142678/10046/1024/10014/83464/7311/55851/51107/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 47 Hepatitis_C_virus_genotype_1a R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 47/6120 58/10654 1.2503856939829233e-4 3.159576753612763e-4 1.188821712445564e-4 8454/79718/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/388585/7314/2648/9734/55869/51564/55534/3280/84441/10013/102/5664/8850/3066/6233/5663/142678/10046/1024/10014/83464/7311/55851/51107/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 47 Hepatitis_C_virus_genotype_1a R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 47/6120 58/10654 1.2503856939829233e-4 3.159576753612763e-4 1.188821712445564e-4 8454/79718/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/388585/7314/2648/9734/55869/51564/55534/3280/84441/10013/102/5664/8850/3066/6233/5663/142678/10046/1024/10014/83464/7311/55851/51107/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 47 Hepatitis_C_virus_genotype_1a R-HSA-110312 Translesion synthesis by REV1 16/6120 16/10654 1.3937693008718902e-4 3.44170703017402e-4 1.2949759934361376e-4 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/7311/5983/7316/10459/5981/5980 16 Hepatitis_C_virus_genotype_1a R-HSA-1295596 Spry regulation of FGF signaling 16/6120 16/10654 1.3937693008718902e-4 3.44170703017402e-4 1.2949759934361376e-4 8569/2885/5518/7314/5515/5594/6714/6233/5781/673/7311/5595/5516/10253/7316/867 16 Hepatitis_C_virus_genotype_1a R-HSA-156711 Polo-like kinase mediated events 16/6120 16/10654 1.3937693008718902e-4 3.44170703017402e-4 1.2949759934361376e-4 5928/7465/993/2305/9133/286826/891/91750/55957/5347/4605/1063/9088/2033/995/132660 16 Hepatitis_C_virus_genotype_1a R-HSA-175474 Assembly Of The HIV Virion 16/6120 16/10654 1.3937693008718902e-4 3.44170703017402e-4 1.2949759934361376e-4 55048/51271/7314/137492/51160/79720/9397/89853/5478/6233/7311/93343/7251/155382/5045/7316 16 Hepatitis_C_virus_genotype_1a R-HSA-193639 p75NTR signals via NF-kB 16/6120 16/10654 1.3937693008718902e-4 3.44170703017402e-4 1.2949759934361376e-4 4790/8878/4792/3654/3551/7314/8767/5970/6233/7189/7311/4804/5584/4615/7316/4803 16 Hepatitis_C_virus_genotype_1a R-HSA-1963640 GRB2 events in ERBB2 signaling 16/6120 16/10654 1.3937693008718902e-4 3.44170703017402e-4 1.2949759934361376e-4 4893/2064/145957/9542/2885/3845/3265/1839/2069/3084/6654/10718/1956/685/1950/2066 16 Hepatitis_C_virus_genotype_1a R-HSA-1963642 PI3K events in ERBB2 signaling 16/6120 16/10654 1.3937693008718902e-4 3.44170703017402e-4 1.2949759934361376e-4 5295/2064/145957/9542/2885/1839/5290/2065/2069/3084/10718/1956/2549/685/1950/2066 16 Hepatitis_C_virus_genotype_1a R-HSA-205043 NRIF signals cell death from the nucleus 16/6120 16/10654 1.3937693008718902e-4 3.44170703017402e-4 1.2949759934361376e-4 8878/23385/7314/5664/6233/5663/7189/83464/7311/55851/51107/4804/23421/7316/4803/5599 16 Hepatitis_C_virus_genotype_1a R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 16/6120 16/10654 1.3937693008718902e-4 3.44170703017402e-4 1.2949759934361376e-4 7040/7314/50848/7046/2280/6233/57530/5590/7048/7311/387/57154/50855/23370/7316/56288 16 Hepatitis_C_virus_genotype_1a R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 16/6120 16/10654 1.3937693008718902e-4 3.44170703017402e-4 1.2949759934361376e-4 5295/5291/2534/2885/9846/5290/5170/6464/2205/2206/6850/4067/6654/7462/5296/2207 16 Hepatitis_C_virus_genotype_1a R-HSA-399954 Sema3A PAK dependent Axon repulsion 16/6120 16/10654 1.3937693008718902e-4 3.44170703017402e-4 1.2949759934361376e-4 5361/8829/2534/5362/5062/5879/1072/10371/55558/5063/3326/5058/3984/3320/91584/2242 16 Hepatitis_C_virus_genotype_1a R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 16/6120 16/10654 1.3937693008718902e-4 3.44170703017402e-4 1.2949759934361376e-4 8454/4790/3551/7314/8945/1326/8517/6233/79155/7311/6416/1147/5604/6500/7316/23291 16 Hepatitis_C_virus_genotype_1a R-HSA-9614657 FOXO-mediated transcription of cell death genes 16/6120 16/10654 1.3937693008718902e-4 3.44170703017402e-4 1.2949759934361376e-4 2308/65018/356/1387/4801/604/4303/4800/10370/6794/27113/2309/10018/4802/1649/2033 16 Hepatitis_C_virus_genotype_1a R-HSA-500657 Presynaptic function of Kainate receptors 20/6120 21/10654 1.4387981005205334e-4 3.5220578502325557e-4 1.3252087767952282e-4 2788/5331/2782/2787/10681/2792/2785/2783/2784/2791/23236/2786/54331/59345/51764/94235/5330/55970/2793/2790 20 Hepatitis_C_virus_genotype_1a R-HSA-5654688 SHC-mediated cascade:FGFR1 20/6120 21/10654 1.4387981005205334e-4 3.5220578502325557e-4 1.3252087767952282e-4 4893/2250/2885/2253/3845/3265/8074/2260/2249/2248/2247/2246/2251/6464/6654/8822/2254/26281/2255/27006 20 Hepatitis_C_virus_genotype_1a R-HSA-5654689 PI-3K cascade:FGFR1 20/6120 21/10654 1.4387981005205334e-4 3.5220578502325557e-4 1.3252087767952282e-4 5295/2250/2885/2253/5290/8074/2260/2249/2248/2247/2246/2251/5781/2549/8822/2254/26281/10818/2255/27006 20 Hepatitis_C_virus_genotype_1a R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 20/6120 21/10654 1.4387981005205334e-4 3.5220578502325557e-4 1.3252087767952282e-4 25904/55571/55835/57472/85456/29883/1263/7832/10769/7157/5325/4869/4850/246175/4848/23019/4849/9337/28984/995 20 Hepatitis_C_virus_genotype_1a R-HSA-6807004 Negative regulation of MET activity 20/6120 21/10654 1.4387981005205334e-4 3.5220578502325557e-4 1.3252087767952282e-4 5770/3082/6456/30011/2885/7314/8027/2060/9101/9146/6455/6233/4233/5795/5771/7311/7316/867/10254/6457 20 Hepatitis_C_virus_genotype_1a R-HSA-3299685 Detoxification of Reactive Oxygen Species 32/6120 37/10654 1.4594249413846575e-4 3.5663590422051417e-4 1.341877534357142e-4 7295/7001/10587/7296/2876/2936/847/9973/2877/538/1535/4688/653361/25828/25824/6648/79400/257202/2880/475/2878/10935/54205/9588/6647/2882/493869/50507/5052/1536/5034/2950 32 Hepatitis_C_virus_genotype_1a R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 37/6120 44/10654 1.5277045911259155e-4 3.726753414338306e-4 1.4022274884856336e-4 7321/8239/9612/4609/4089/22938/23327/4088/1030/904/7314/5054/7027/6497/51592/7323/6667/4092/6233/1025/4221/3726/1024/60436/8812/1874/142/4087/7311/64750/54778/7316/9611/5933/3065/6498/25937 37 Hepatitis_C_virus_genotype_1a R-HSA-202433 Generation of second messenger molecules 29/6120 33/10654 1.6545721712144697e-4 4.015398900881932e-4 1.5108331810709174e-4 5335/3115/3113/3117/3127/5062/3126/916/3702/3932/3120/3937/3123/3122/920/5063/7535/3125/5058/55740/9402/4690/3119/919/27040/915/917/7408/7454 29 Hepatitis_C_virus_genotype_1a R-HSA-2559585 Oncogene Induced Senescence 29/6120 33/10654 1.6545721712144697e-4 4.015398900881932e-4 1.5108331810709174e-4 2077/27327/5925/2114/1869/4194/1031/192669/1032/1030/4343/7314/7027/5594/6667/7157/6233/26523/1019/1029/7311/2113/5595/57690/192670/7316/1021/23112/4193 29 Hepatitis_C_virus_genotype_1a R-HSA-8964043 Plasma lipoprotein clearance 29/6120 33/10654 1.6545721712144697e-4 4.015398900881932e-4 1.5108331810709174e-4 346/10577/51599/55911/949/163/10062/161/7436/348/3069/26119/1213/1211/1175/29116/1173/160/341/338/335/3990/255738/57552/3988/6646/3949/7376/4864 29 Hepatitis_C_virus_genotype_1a R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 23/6120 25/10654 1.738611206902645e-4 4.1833477845268423e-4 1.574025594178073e-4 2308/2475/7249/2932/10000/2931/253260/5170/572/4303/6199/64223/208/79109/1147/2309/842/207/1027/1026/3164/1385/4193 23 Hepatitis_C_virus_genotype_1a R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 23/6120 25/10654 1.738611206902645e-4 4.1833477845268423e-4 1.574025594178073e-4 51400/5520/8900/5518/7465/5515/993/890/983/5519/7514/2305/9133/891/4331/5347/5516/1017/994/902/9088/995/1022 23 Hepatitis_C_virus_genotype_1a R-HSA-937041 IKK complex recruitment mediated by RIP1 23/6120 25/10654 1.738611206902645e-4 4.1833477845268423e-4 1.574025594178073e-4 7321/929/7334/3551/7314/23098/11035/8737/8517/7323/6233/330/7189/7311/23643/1147/7099/7316/7335/7322/329/353376/148022 23 Hepatitis_C_virus_genotype_1a R-HSA-9620244 Long-term potentiation 23/6120 25/10654 1.738611206902645e-4 4.1833477845268423e-4 1.574025594178073e-4 817/1741/1739/1740/818/57554/2902/6714/2906/801/2891/4747/805/2904/2905/3084/816/815/2903/2066/1742/88/808 23 Hepatitis_C_virus_genotype_1a R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 23/6120 25/10654 1.738611206902645e-4 4.1833477845268423e-4 1.574025594178073e-4 3107/10484/811/567/3106/3309/9632/3133/6892/22872/10134/51128/6396/3135/10802/6890/821/2923/9871/3105/6891/3134/10427 23 Hepatitis_C_virus_genotype_1a R-HSA-5218920 VEGFR2 mediated vascular permeability 26/6120 29/10654 1.7748936263385984e-4 4.2561224713221494e-4 1.6014077831626454e-4 857/2475/5062/5879/1500/10000/3728/7410/7409/801/253260/805/5170/10451/64223/1003/5063/208/79109/5058/1495/1499/207/3320/4846/808 26 Hepatitis_C_virus_genotype_1a R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 26/6120 29/10654 1.7748936263385984e-4 4.2561224713221494e-4 1.6014077831626454e-4 5431/5435/5433/55124/84944/5439/11022/91646/5438/56165/54514/5434/5436/122402/143689/5432/4603/5440/8468/5430/5441/5437/3320/54456/9271/136991 26 Hepatitis_C_virus_genotype_1a R-HSA-1474244 Extracellular matrix organization 203/6120 301/10654 1.97681314382046e-4 4.7322691558350575e-4 1.7805626387016566e-4 3675/8174/871/169044/6385/960/3696/7042/1511/5175/256076/5578/84171/23385/3383/54829/1280/1289/84695/7448/6696/1300/4684/3688/1509/176/4054/3693/3910/1290/1303/836/2244/1605/3690/3694/2200/3385/87/84467/6868/4325/6382/7040/1285/30008/1296/7043/63827/5054/3655/255631/50859/826/1294/3918/7373/633/4316/6678/5340/375790/4320/26254/7412/5644/823/1284/4680/284217/1305/2006/4312/1307/50848/4313/3672/1298/102/5339/84570/4148/5033/999/2247/2335/3909/1295/1288/726/4326/2266/3685/1292/5154/7076/2243/3791/1293/57642/9672/3691/5663/5645/1302/1291/1508/1514/7077/1310/1286/1287/8573/7276/1308/351/655/5352/4052/8754/91522/3674/3684/3384/83700/4318/3678/1277/3912/3695/5802/4322/3818/8751/3913/5654/652/4060/81578/7450/222663/340267/4321/4317/5650/2331/5479/3676/4319/51399/3371/1282/85301/10491/4239/283208/1299/1991/3339/8974/136227/5045/1634/79709/6383/831/649/4314/667/3915/1301/1462/824/1281/1297/3673/682/1758/1088/4593/3914/170692/2/1306/1520/8425/780/5155/8516/50509/3687/3680/131873/2202/80781/7057/1278/3689/977/4323/4921/5034/3682 203 Hepatitis_C_virus_genotype_1a R-HSA-8939211 ESR-mediated signaling 154/6120 223/10654 2.082449965505704e-4 4.97670245993736e-4 1.8725330644333186e-4 5295/2788/3725/4893/857/7764/7031/2770/7039/27327/10274/5431/5435/5433/1509/5469/1105/4609/1387/8312/2782/5439/192669/10499/1386/4343/3845/904/3265/8877/2773/2787/6387/1839/5290/4316/5594/2069/10681/5481/5438/4313/865/1655/6667/2792/6714/2099/2494/8850/10000/2785/595/2783/2784/2771/7514/1025/2353/255324/26523/801/2791/2957/805/5170/2963/3838/5434/5590/6464/7090/5241/5747/5436/1903/3315/4318/200845/5885/57678/7033/2962/8503/10524/8243/4602/2786/208/3326/23030/6908/1956/5536/3169/858/5432/3480/10728/5595/7528/3727/27161/7392/596/5440/685/54331/4435/2309/9687/59345/8204/5430/207/5451/2625/57690/6722/1027/51764/94235/5441/10735/192670/2100/1950/55970/4314/346562/2289/7391/2958/5437/2793/3320/2033/4846/9126/3065/2002/2066/861/23028/23112/10498/1385/5296/808/3276/8202/8648/2288/2790 154 Hepatitis_C_virus_genotype_1a R-HSA-1474228 Degradation of the extracellular matrix 101/6120 140/10654 2.0986557061219023e-4 5.006945085671543e-4 1.8839121486961238e-4 960/1511/256076/23385/1280/1289/6696/1300/1509/176/1290/1303/836/2200/84467/6868/4325/1285/1296/63827/50859/826/1294/3918/7373/4316/5340/4320/26254/5644/823/1284/1305/2006/4312/1307/4313/1298/102/84570/999/2335/3909/1295/1288/726/4326/1292/7076/1293/5663/5645/1302/1291/1508/1514/7077/1310/1286/1287/1308/8754/91522/4318/1277/3912/4322/3818/8751/5654/222663/4321/4317/5650/4319/1282/1299/1991/3339/136227/5045/1634/831/649/4314/3915/1301/824/1281/1297/682/3914/170692/2/1306/1520/50509/131873/80781/1278/4323 101 Hepatitis_C_virus_genotype_1a R-HSA-202733 Cell surface interactions at the vascular wall 99/6120 137/10654 2.1829515518094066e-4 5.199259608194701e-4 1.9562723721762822e-4 5295/3675/5777/4893/857/5335/6385/960/5291/7056/2995/5175/3688/972/2534/3690/2885/51206/4072/5676/6382/5673/7040/3845/4282/3265/3655/3635/5290/5680/6401/4680/4312/50848/6714/8797/4973/914/2335/5671/5478/7525/3685/3932/9672/5781/5672/2147/6464/483/3684/7010/1048/10461/83700/3678/1277/338/5670/8140/4267/6403/4067/140885/5624/6402/6654/23657/285/3897/8795/5669/3676/9123/2817/8793/5675/1525/6383/5196/2621/83953/54210/682/1088/23759/5678/6520/440533/5296/3687/1278/481/3689/2207/5627/6566/284/9046 99 Hepatitis_C_virus_genotype_1a R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 19/6120 20/10654 2.3956100690225343e-4 5.586819923948149e-4 2.1020957384620137e-4 7321/7334/3551/7314/11035/8737/8517/7323/6233/330/7098/7189/7311/1147/7316/7335/7322/329/148022 19 Hepatitis_C_virus_genotype_1a R-HSA-3232118 SUMOylation of transcription factors 19/6120 20/10654 2.3956100690225343e-4 5.586819923948149e-4 2.1020957384620137e-4 9112/6613/7022/6612/4286/6670/51588/7157/7158/9063/8554/7020/1029/7329/7021/3090/7341/10401/4193 19 Hepatitis_C_virus_genotype_1a R-HSA-5625900 RHO GTPases activate CIT 19/6120 20/10654 2.3956100690225343e-4 5.586819923948149e-4 2.1020957384620137e-4 388/79784/4628/5879/4659/389/11113/9055/5500/10627/387/4660/4627/1027/10398/4637/1742/9928/103910 19 Hepatitis_C_virus_genotype_1a R-HSA-5627117 RHO GTPases Activate ROCKs 19/6120 20/10654 2.3956100690225343e-4 5.586819923948149e-4 2.1020957384620137e-4 388/79784/9475/4628/6093/1072/4659/389/5500/10627/387/5058/4660/3984/4627/3985/10398/4637/103910 19 Hepatitis_C_virus_genotype_1a R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 19/6120 20/10654 2.3956100690225343e-4 5.586819923948149e-4 2.1020957384620137e-4 472/1387/51499/7159/637/27166/23368/7157/63970/55240/5366/84883/147923/94241/8626/7161/665/27113/581 19 Hepatitis_C_virus_genotype_1a R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 19/6120 20/10654 2.3956100690225343e-4 5.586819923948149e-4 2.1020957384620137e-4 22938/1387/4088/4853/9794/388585/2648/55534/3280/84441/8850/2324/10046/59/4855/4851/23462/2033/3516 19 Hepatitis_C_virus_genotype_1a R-HSA-111447 Activation of BAD and translocation to mitochondria 15/6120 15/10654 2.4288798676455427e-4 5.586819923948149e-4 2.1020957384620137e-4 7531/10971/7533/2810/637/7534/10000/572/7532/208/7529/5533/596/207/5534 15 Hepatitis_C_virus_genotype_1a R-HSA-354194 GRB2:SOS provides linkage to MAPK signaling for Integrins 15/6120 15/10654 2.4288798676455427e-4 5.586819923948149e-4 2.1020957384620137e-4 5908/2244/3690/2885/7094/6714/2335/2266/2243/5747/3674/6654/7450/54518/5906 15 Hepatitis_C_virus_genotype_1a R-HSA-372708 p130Cas linkage to MAPK signaling for integrins 15/6120 15/10654 2.4288798676455427e-4 5.586819923948149e-4 2.1020957384620137e-4 5908/2244/3690/9564/7094/6714/2335/2266/2243/5747/3674/7450/54518/1398/5906 15 Hepatitis_C_virus_genotype_1a R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 15/6120 15/10654 2.4288798676455427e-4 5.586819923948149e-4 2.1020957384620137e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Hepatitis_C_virus_genotype_1a R-HSA-5099900 WNT5A-dependent internalization of FZD4 15/6120 15/10654 2.4288798676455427e-4 5.586819923948149e-4 2.1020957384620137e-4 5579/5578/1212/5582/163/161/1856/8322/7474/1213/1211/1175/1173/409/160 15 Hepatitis_C_virus_genotype_1a R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 15/6120 15/10654 2.4288798676455427e-4 5.586819923948149e-4 2.1020957384620137e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Hepatitis_C_virus_genotype_1a R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 15/6120 15/10654 2.4288798676455427e-4 5.586819923948149e-4 2.1020957384620137e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Hepatitis_C_virus_genotype_1a R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 15/6120 15/10654 2.4288798676455427e-4 5.586819923948149e-4 2.1020957384620137e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Hepatitis_C_virus_genotype_1a R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 15/6120 15/10654 2.4288798676455427e-4 5.586819923948149e-4 2.1020957384620137e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Hepatitis_C_virus_genotype_1a R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 15/6120 15/10654 2.4288798676455427e-4 5.586819923948149e-4 2.1020957384620137e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Hepatitis_C_virus_genotype_1a R-HSA-5637810 Constitutive Signaling by EGFRvIII 15/6120 15/10654 2.4288798676455427e-4 5.586819923948149e-4 2.1020957384620137e-4 5295/4893/5335/2885/3845/3265/5290/6464/6654/1956/2549/11140/1950/867/3320 15 Hepatitis_C_virus_genotype_1a R-HSA-5637812 Signaling by EGFRvIII in Cancer 15/6120 15/10654 2.4288798676455427e-4 5.586819923948149e-4 2.1020957384620137e-4 5295/4893/5335/2885/3845/3265/5290/6464/6654/1956/2549/11140/1950/867/3320 15 Hepatitis_C_virus_genotype_1a R-HSA-5654228 Phospholipase C-mediated cascade; FGFR4 15/6120 15/10654 2.4288798676455427e-4 5.586819923948149e-4 2.1020957384620137e-4 5335/9965/2264/2253/8823/8074/2249/2247/2246/2251/8822/8817/2254/152831/26281 15 Hepatitis_C_virus_genotype_1a R-HSA-6785631 ERBB2 Regulates Cell Motility 15/6120 15/10654 2.4288798676455427e-4 5.586819923948149e-4 2.1020957384620137e-4 2064/145957/9542/1839/2065/2069/1729/3084/10718/387/1956/685/1950/51072/2066 15 Hepatitis_C_virus_genotype_1a R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 15/6120 15/10654 2.4288798676455427e-4 5.586819923948149e-4 2.1020957384620137e-4 6456/30011/2885/7314/8027/2060/9146/6455/6233/4233/7311/7316/867/10254/6457 15 Hepatitis_C_virus_genotype_1a R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 64/6120 84/10654 2.5204041581438957e-4 5.787898799646406e-4 2.1777536357012233e-4 7124/1052/4790/79718/9441/5469/9612/1387/6907/84246/4023/55588/10499/7040/9282/51129/7471/3952/5465/5970/6604/9439/896/9370/9412/9969/54797/7480/5105/55090/1019/9440/6721/9862/1051/1050/1024/9314/9968/10001/9443/9477/51586/6517/8841/5468/29079/168544/90390/6720/6837/688/9611/81857/2033/9967/6256/51003/10498/948/112950/8202/8648/10891 64 Hepatitis_C_virus_genotype_1a R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 87/6120 119/10654 2.7025469604146035e-4 6.196083275096895e-4 2.331337044157399e-4 79718/9441/34/1543/5469/9612/11010/1387/6907/2101/84246/4801/2274/1376/55588/10499/1581/9282/10062/7296/51129/5465/3157/6667/23309/336/3156/6604/9439/4199/123/2168/183/116519/6257/9412/9969/405/133522/54797/55090/1374/9440/6721/51/9862/23179/406/19/335/4800/1024/9968/10001/9971/9443/211/9477/25942/51586/6095/6822/8841/5468/29079/4802/4862/90390/6720/6837/9611/2874/81857/2033/9967/6256/51003/7376/10498/948/112950/196/4520/8202/8648/2180/10891 87 Hepatitis_C_virus_genotype_1a R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 33/6120 39/10654 2.781077126161334e-4 6.365777188129027e-4 2.395186041670049e-4 5982/25898/6117/10714/55666/7314/6118/9636/11201/51455/5985/5984/6233/5424/124739/7706/5111/6119/83932/5427/5429/9246/51426/7311/7318/5983/7316/5426/9100/10459/7415/5981/5980 33 Hepatitis_C_virus_genotype_1a R-HSA-69205 G1/S-Specific Transcription 25/6120 28/10654 2.7908145785850445e-4 6.367392485121218e-4 2.3957938129907385e-4 5422/1869/4998/5928/990/8900/6241/7027/898/5934/983/7298/1719/26271/8318/286826/5111/91750/1874/81620/55957/5933/3065/7083/132660 25 Hepatitis_C_virus_genotype_1a R-HSA-75067 Processing of Capped Intronless Pre-mRNA 25/6120 28/10654 2.7908145785850445e-4 6.367392485121218e-4 2.3957938129907385e-4 51585/81608/1477/53981/134353/11051/8106/1478/23283/6636/10914/6635/6637/10898/51692/22916/1479/79869/29894/4686/8189/10978/6634/55339/6628 25 Hepatitis_C_virus_genotype_1a R-HSA-3371571 HSF1-dependent transactivation 22/6120 24/10654 2.801791494142131e-4 6.371816139903878e-4 2.3974582564475957e-4 817/3305/1387/2475/3306/3312/818/3303/3337/3297/57521/1410/64223/3281/816/3326/3304/10728/815/3320/2033/2288 22 Hepatitis_C_virus_genotype_1a R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 22/6120 24/10654 2.801791494142131e-4 6.371816139903878e-4 2.3974582564475957e-4 7039/1839/5594/2069/10000/595/7514/2353/255324/5747/208/1956/5595/596/685/2309/207/6722/1027/1950/2002/1385 22 Hepatitis_C_virus_genotype_1a R-HSA-8953750 Transcriptional Regulation by E2F6 30/6120 35/10654 3.3535608093631714e-4 7.614365122708649e-4 2.864979486259918e-4 6045/80012/79813/11335/1869/1911/5928/10138/23512/672/6241/5888/7027/2146/100532731/8726/8409/7703/317/23429/6015/84108/5931/1111/648/23468/8317/4149/5932/10919 30 Hepatitis_C_virus_genotype_1a R-HSA-166658 Complement cascade 46/6120 58/10654 3.823263845029159e-4 8.666884278924621e-4 3.261000131823822e-4 730/5199/10584/7448/717/1380/975/732/2219/720/714/729/5648/727/629/722/27202/1401/731/712/716/1191/78989/721/725/728/4179/2147/930/1378/10747/1361/715/3426/2220/735/1991/1604/710/1675/719/713/8547/4153/5627/718 46 Hepatitis_C_virus_genotype_1a R-HSA-110320 Translesion Synthesis by POLH 18/6120 19/10654 3.979681119399091e-4 8.978160605364349e-4 3.378120899666766e-4 5982/25898/6117/55666/7314/6118/5985/5984/6233/5111/6119/83932/5429/7311/5983/7316/7415/5981 18 Hepatitis_C_virus_genotype_1a R-HSA-202430 Translocation of ZAP-70 to Immunological synapse 18/6120 19/10654 3.979681119399091e-4 8.978160605364349e-4 3.378120899666766e-4 3115/3113/3117/26191/3127/3126/916/3932/3120/3123/3122/920/7535/3125/3119/919/915/917 18 Hepatitis_C_virus_genotype_1a R-HSA-6804760 Regulation of TP53 Activity through Methylation 18/6120 19/10654 3.979681119399091e-4 8.978160605364349e-4 3.378120899666766e-4 133383/11200/472/79813/4194/56950/7314/7157/6233/10419/26013/7311/7316/2033/91875/133746/10919/4193 18 Hepatitis_C_virus_genotype_1a R-HSA-5696394 DNA Damage Recognition in GG-NER 32/6120 38/10654 4.137542825253571e-4 9.167037062677521e-4 3.4491875174240167e-4 10445/9978/10980/10987/7314/83444/86/1643/10920/6233/93973/8607/5886/8451/8450/1642/142/1069/2873/7311/60/8533/51138/7528/9318/7316/64708/283899/4798/5887/50813/7508 32 Hepatitis_C_virus_genotype_1a R-HSA-1250347 SHC1 events in ERBB4 signaling 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 4893/145957/9542/2885/3845/3265/1839/2069/6464/3084/6654/10718/685/2066 14 Hepatitis_C_virus_genotype_1a R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 5861/2801/5594/983/8548/8615/9133/891/81876/5347/5595/5862/26003/64689 14 Hepatitis_C_virus_genotype_1a R-HSA-166786 Creation of C4 and C2 activators 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 10584/2219/714/5648/1401/712/716/78989/10747/715/2220/713/8547/4153 14 Hepatitis_C_virus_genotype_1a R-HSA-169893 Prolonged ERK activation events 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 5605/1399/5594/4914/673/2889/7529/5595/5604/57498/10818/4803/1398/5906 14 Hepatitis_C_virus_genotype_1a R-HSA-174490 Membrane binding and targetting of GAG proteins 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 55048/51271/7314/137492/51160/79720/9397/89853/6233/7311/93343/7251/155382/7316 14 Hepatitis_C_virus_genotype_1a R-HSA-174495 Synthesis And Processing Of GAG, GAGPOL Polyproteins 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 55048/51271/7314/137492/51160/79720/9397/89853/6233/7311/93343/7251/155382/7316 14 Hepatitis_C_virus_genotype_1a R-HSA-190322 FGFR4 ligand binding and activation 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 9965/2264/2253/8823/8074/2249/2247/2246/2251/8822/8817/2254/152831/26281 14 Hepatitis_C_virus_genotype_1a R-HSA-3371568 Attenuation phase 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 3305/1387/3306/3312/3303/3337/3297/3281/3326/3304/10728/3320/2033/2288 14 Hepatitis_C_virus_genotype_1a R-HSA-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 107/5567/5573/5613/801/805/5568/5566/5577/5575/114/5576/1385/808 14 Hepatitis_C_virus_genotype_1a R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Hepatitis_C_virus_genotype_1a R-HSA-4839744 truncated APC mutants destabilize the destruction complex 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Hepatitis_C_virus_genotype_1a R-HSA-4839748 AMER1 mutants destabilize the destruction complex 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Hepatitis_C_virus_genotype_1a R-HSA-5467337 APC truncation mutants have impaired AXIN binding 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Hepatitis_C_virus_genotype_1a R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Hepatitis_C_virus_genotype_1a R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Hepatitis_C_virus_genotype_1a R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 79370/7159/23368/332/64065/7157/1121/604/5875/8626/7161/10397/9540/5876 14 Hepatitis_C_virus_genotype_1a R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 9134/57060/1869/8900/144455/898/890/7157/79733/1820/1017/25946/1027/1026 14 Hepatitis_C_virus_genotype_1a R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 7159/51230/23368/5458/10000/7157/5457/54971/8626/208/7161/25946/207/10848 14 Hepatitis_C_virus_genotype_1a R-HSA-877312 Regulation of IFNG signaling 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 5777/5770/9021/3459/3717/3458/5781/8554/6772/8651/5771/3716/3460/7341 14 Hepatitis_C_virus_genotype_1a R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 4893/2909/5753/9564/3845/3265/5829/5879/5921/1793/387/63916/1398/9844 14 Hepatitis_C_virus_genotype_1a R-HSA-8941856 RUNX3 regulates NOTCH signaling 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 182/22938/1387/9794/2648/55534/3280/84441/8850/864/10046/4851/2033/3516 14 Hepatitis_C_virus_genotype_1a R-HSA-8983432 Interleukin-15 signaling 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 6776/2885/9846/3600/3718/6777/6464/6774/6654/3716/6655/3561/3560/3601 14 Hepatitis_C_virus_genotype_1a R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 79718/9612/6907/4204/814/801/805/5566/25942/8841/9611/2874/3065/808 14 Hepatitis_C_virus_genotype_1a R-HSA-9005895 Pervasive developmental disorders 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 79718/9612/6907/4204/814/801/805/5566/25942/8841/9611/2874/3065/808 14 Hepatitis_C_virus_genotype_1a R-HSA-9027284 Erythropoietin activates RAS 14/6120 14/10654 4.232440516172387e-4 9.167037062677521e-4 3.4491875174240167e-4 4893/3717/2885/2056/8660/3845/3265/1399/2057/7409/6464/2889/4067/6654 14 Hepatitis_C_virus_genotype_1a R-HSA-70326 Glucose metabolism 68/6120 91/10654 4.395309354512848e-4 9.505193542734841e-4 3.5764222064489437e-4 23165/7167/5313/2806/8402/5211/348995/57122/3099/6576/23511/23279/5106/23225/9972/5518/2538/4191/8021/2026/55746/2027/5515/2597/5567/1468/10762/5528/79902/5519/9883/226/2821/8604/2645/6396/129401/230/5105/4928/5903/55706/7175/2203/5568/2805/4927/5566/2023/4190/669/8086/5516/81929/9631/5091/5315/79023/23636/5214/53371/5230/10165/3098/9688/5210/5213/8480 68 Hepatitis_C_virus_genotype_1a R-HSA-1989781 PPARA activates gene expression 85/6120 117/10654 4.477386043404093e-4 9.66786266646213e-4 3.6376280581537244e-4 79718/9441/34/1543/5469/9612/11010/1387/6907/2101/84246/4801/2274/1376/55588/10499/1581/9282/10062/7296/51129/5465/3157/6667/336/3156/6604/9439/4199/123/2168/183/116519/6257/9412/9969/405/133522/54797/55090/1374/9440/6721/51/9862/23179/406/19/335/4800/1024/9968/10001/9971/9443/211/9477/51586/6095/6822/8841/5468/29079/4802/4862/90390/6720/6837/9611/2874/81857/2033/9967/6256/51003/7376/10498/948/112950/196/4520/8202/8648/2180/10891 85 Hepatitis_C_virus_genotype_1a R-HSA-166663 Initial triggering of complement 21/6120 23/10654 4.5003987929740697e-4 9.673113259288778e-4 3.6396036451523286e-4 5199/10584/717/2219/720/714/5648/629/1401/712/716/78989/721/10747/715/2220/1675/713/8547/4153/718 21 Hepatitis_C_virus_genotype_1a R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 21/6120 23/10654 4.5003987929740697e-4 9.673113259288778e-4 3.6396036451523286e-4 7321/8239/9612/4089/23327/4088/7314/6497/51592/7323/6233/60436/142/4087/7311/64750/54778/7316/9611/3065/6498 21 Hepatitis_C_virus_genotype_1a R-HSA-9617324 Negative regulation of NMDA receptor-mediated neuronal transmission 21/6120 23/10654 4.5003987929740697e-4 9.673113259288778e-4 3.6396036451523286e-4 817/1741/1739/1740/814/818/57554/2902/2906/801/4747/805/2904/2905/816/815/2903/1742/88/808/8536 21 Hepatitis_C_virus_genotype_1a R-HSA-5696400 Dual Incision in GG-NER 34/6120 41/10654 4.874664835453038e-4 0.001044571036168508 3.930300875169303e-4 5982/9978/2965/2067/2967/6117/10714/7314/6118/404672/9557/1643/5985/2068/5984/6233/5424/8451/8450/5111/2966/6119/5427/1642/142/2071/51426/7311/5983/2072/7316/5426/2968/5981 34 Hepatitis_C_virus_genotype_1a R-HSA-9609736 Assembly and cell surface presentation of NMDA receptors 34/6120 41/10654 4.874664835453038e-4 0.001044571036168508 3.930300875169303e-4 51807/817/10381/7278/7846/113457/1741/1739/1740/818/57554/79861/2902/10376/2906/4747/57576/84617/8573/2904/10382/7277/55327/2905/347733/816/10383/84790/7280/815/112714/2903/1742/88 34 Hepatitis_C_virus_genotype_1a R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 26/6120 30/10654 6.000049106675557e-4 0.001281828672789778 4.823005980485616e-4 56852/5982/9978/57599/6117/10714/7314/51514/6118/5985/5984/6233/5424/8451/8450/5111/6119/5427/1642/7311/5983/7320/7316/5426/7398/5981 26 Hepatitis_C_virus_genotype_1a R-HSA-525793 Myogenesis 26/6120 30/10654 6.000049106675557e-4 0.001281828672789778 4.823005980485616e-4 9043/663/4617/1432/25/1496/4208/4654/5600/6300/4656/5608/6929/91653/6938/4209/1002/1000/998/6925/4756/1495/1499/50937/4205/1013 26 Hepatitis_C_virus_genotype_1a R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 17/6120 18/10654 6.594777415212092e-4 0.001400397011362809 5.26913097220497e-4 5295/11052/613/6776/11064/2885/9846/7750/8805/26127/5290/399687/6777/1523/9208/6774/6772 17 Hepatitis_C_virus_genotype_1a R-HSA-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 17/6120 18/10654 6.594777415212092e-4 0.001400397011362809 5.26913097220497e-4 8792/10673/8740/7187/51330/958/9020/8742/959/4055/8600/330/115650/4050/7186/329/4049 17 Hepatitis_C_virus_genotype_1a R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 17/6120 18/10654 6.594777415212092e-4 0.001400397011362809 5.26913097220497e-4 2810/6790/1647/7027/5934/983/7157/891/5111/1874/25946/5933/2033/995/10498/581/3276 17 Hepatitis_C_virus_genotype_1a R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 17/6120 18/10654 6.594777415212092e-4 0.001400397011362809 5.26913097220497e-4 929/7187/7314/23098/29110/3661/6233/10010/5781/3665/7311/9641/23643/7099/7316/353376/148022 17 Hepatitis_C_virus_genotype_1a R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 23/6120 26/10654 6.821617911505135e-4 0.0014463881586800362 5.442177170397449e-4 83990/5892/9156/1763/7486/472/4683/672/5888/116028/7517/80010/580/641/10524/5889/79728/10111/675/10635/5932/7156/5890 23 Hepatitis_C_virus_genotype_1a R-HSA-1660499 Synthesis of PIPs at the plasma membrane 42/6120 53/10654 7.08310473835632e-4 0.0014995762283907526 5.642302494280996e-4 5295/5291/5783/5286/55300/8871/660/4534/51552/8396/54477/23396/3635/5290/5868/59339/3631/80230/81846/79837/8395/55361/146850/5294/8394/8898/22874/8867/8503/3636/59338/5867/5293/5305/8897/64419/5287/23533/5728/5296/375/4952 42 Hepatitis_C_virus_genotype_1a R-HSA-9613829 Chaperone Mediated Autophagy 20/6120 22/10654 7.203291010162454e-4 0.0015227346813087047 5.729438442550111e-4 2670/1915/5116/3043/3920/3312/11315/7314/10013/123/6233/1068/3326/7311/1080/7316/10226/3320/200894/7431 20 Hepatitis_C_virus_genotype_1a R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 13/6120 13/10654 7.374717460715633e-4 0.0015269238795314307 5.745200711338867e-4 2064/9542/7314/2065/9101/10000/6233/10193/3084/208/7311/207/7316 13 Hepatitis_C_virus_genotype_1a R-HSA-171007 p38MAPK events 13/6120 13/10654 7.374717460715633e-4 0.0015269238795314307 5.745200711338867e-4 4893/5898/1432/5603/3845/3265/5899/9261/6714/5600/6300/7867/5900 13 Hepatitis_C_virus_genotype_1a R-HSA-190375 FGFR2c ligand binding and activation 13/6120 13/10654 7.374717460715633e-4 0.0015269238795314307 5.745200711338867e-4 2250/2253/8823/8074/2249/2247/2246/2251/2263/8822/8817/2254/26281 13 Hepatitis_C_virus_genotype_1a R-HSA-202670 ERKs are inactivated 13/6120 13/10654 7.374717460715633e-4 0.0015269238795314307 5.745200711338867e-4 1848/5518/51231/5515/1849/5594/5528/5519/5598/1846/5595/5516/1845 13 Hepatitis_C_virus_genotype_1a R-HSA-209543 p75NTR recruits signalling complexes 13/6120 13/10654 7.374717460715633e-4 0.0015269238795314307 5.745200711338867e-4 8878/3654/3551/7314/8767/6233/7189/7311/4804/5584/4615/7316/4803 13 Hepatitis_C_virus_genotype_1a R-HSA-209560 NF-kB is activated and signals survival 13/6120 13/10654 7.374717460715633e-4 0.0015269238795314307 5.745200711338867e-4 4790/8878/4792/3654/3551/7314/5970/6233/7189/7311/4804/7316/4803 13 Hepatitis_C_virus_genotype_1a R-HSA-2892247 POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation 13/6120 13/10654 7.374717460715633e-4 0.0015269238795314307 5.745200711338867e-4 6299/6657/55211/27022/5460/2041/2247/2649/6774/79923/7547/6997/57167 13 Hepatitis_C_virus_genotype_1a R-HSA-5140745 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 13/6120 13/10654 7.374717460715633e-4 0.0015269238795314307 5.745200711338867e-4 1212/163/4920/2535/161/7474/1213/1211/7855/1175/1173/160/4919 13 Hepatitis_C_virus_genotype_1a R-HSA-5357786 TNFR1-induced proapoptotic signaling 13/6120 13/10654 7.374717460715633e-4 0.0015269238795314307 5.745200711338867e-4 7124/7375/1540/8737/841/7128/8772/8717/27005/7186/56957/7132/9099 13 Hepatitis_C_virus_genotype_1a R-HSA-5654227 Phospholipase C-mediated cascade; FGFR3 13/6120 13/10654 7.374717460715633e-4 0.0015269238795314307 5.745200711338867e-4 2250/5335/2253/8823/8074/2249/2247/2246/8822/8817/2254/26281/2261 13 Hepatitis_C_virus_genotype_1a R-HSA-5658623 FGFRL1 modulation of FGFR1 signaling 13/6120 13/10654 7.374717460715633e-4 0.0015269238795314307 5.745200711338867e-4 2250/2253/8074/2249/2248/2247/200734/53834/8822/8817/2255/27006/161742 13 Hepatitis_C_virus_genotype_1a R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13/6120 13/10654 7.374717460715633e-4 0.0015269238795314307 5.745200711338867e-4 7531/10971/7533/2810/11200/7465/7534/983/7532/891/1111/7529/995 13 Hepatitis_C_virus_genotype_1a R-HSA-879415 Advanced glycosylation endproduct receptor signaling 13/6120 13/10654 7.374717460715633e-4 0.0015269238795314307 5.745200711338867e-4 177/6283/5594/351/1650/830/3958/829/5595/5589/3146/6288/6285 13 Hepatitis_C_virus_genotype_1a R-HSA-8847993 ERBB2 Activates PTK6 Signaling 13/6120 13/10654 7.374717460715633e-4 0.0015269238795314307 5.745200711338867e-4 2064/5753/145957/9542/1839/2065/2069/3084/10718/1956/685/1950/2066 13 Hepatitis_C_virus_genotype_1a R-HSA-5693568 Resolution of D-loop Structures through Holliday Junction Intermediates 28/6120 33/10654 7.578567446099399e-4 0.0015668299265396118 5.895351123374128e-4 83990/5892/9156/1763/7486/472/80198/4683/672/348654/5888/116028/7517/84464/80010/580/641/10524/5889/79728/146956/10111/675/79008/10635/5932/7156/5890 28 Hepatitis_C_virus_genotype_1a R-HSA-70171 Glycolysis 54/6120 71/10654 8.170828451209256e-4 0.0016868035309231407 6.3467635653995e-4 23165/7167/5313/5211/348995/57122/3099/23511/23279/23225/9972/5518/8021/2026/55746/2027/5515/2597/5567/10762/5528/79902/5519/9883/226/2821/2645/6396/129401/230/4928/5903/55706/7175/5568/4927/5566/2023/669/8086/5516/81929/9631/5315/79023/23636/5214/53371/5230/3098/9688/5210/5213/8480 54 Hepatitis_C_virus_genotype_1a R-HSA-8854214 TBC/RABGAPs 37/6120 46/10654 8.746649957317152e-4 0.0018030374912013428 6.784105230052084e-4 5869/83874/51762/9230/83452/5868/128637/7249/23637/26000/5870/8408/64786/4218/7879/26088/27342/414060/9363/382/9135/5867/10133/11345/7248/23062/11337/51256/8766/51560/11021/79735/81631/5878/23163/338382/57465 37 Hepatitis_C_virus_genotype_1a R-HSA-933541 TRAF6 mediated IRF7 activation 25/6120 29/10654 9.140320530125347e-4 0.0018814382405075531 7.079095731361008e-4 3443/1387/64135/3445/29110/3444/23586/3451/3448/3661/3439/10010/3452/3446/3665/7706/3440/7189/9641/3456/3441/7186/57506/3449/2033 25 Hepatitis_C_virus_genotype_1a R-HSA-75153 Apoptotic execution phase 41/6120 52/10654 9.895629510133354e-4 0.002033941342461812 7.652903595377032e-4 2339/10059/660/836/324/9414/4001/3836/6709/6093/840/5062/2934/22985/63967/841/100506658/7082/5339/28988/10134/999/5588/5580/839/1828/5747/118/1829/8428/1832/3148/4000/3837/1499/3146/329/4137/1677/7431/6304 41 Hepatitis_C_virus_genotype_1a R-HSA-201681 TCF dependent signaling in response to WNT 157/6120 233/10654 0.0010647172058285395 0.0021852274530105398 8.222132409983665e-4 56998/27123/9070/5689/857/7478/5682/1459/5526/1452/5929/1460/143471/5705/6657/8452/55366/5709/9978/5695/1457/4609/5711/1387/5683/324/5699/8312/5702/1855/6932/90780/79412/5518/25776/6659/80351/5696/5691/7314/5515/5718/51176/8945/2535/6662/5700/122706/5707/1856/8549/7473/1454/8322/8325/23198/9101/7471/8395/7534/5528/7091/89780/83439/59349/9861/81847/5519/2932/8321/9580/11197/5698/5692/6422/5713/5710/284654/8313/5719/6233/7474/1857/7514/4040/7479/7855/7089/331/8607/6658/4221/123169/22943/7090/6597/864/10023/4041/79577/283149/5706/23401/8658/5714/6934/10524/5688/5687/607/5708/51339/5529/7088/7483/208/57680/5704/7311/5694/55553/5516/5684/8295/5720/7015/1487/1499/5525/139285/207/8085/5690/5717/9491/10197/64750/7316/10213/54361/64321/5715/5701/1455/5685/5686/2033/54894/3065/5527/5716/23072/26108/9736/5693/5721/6259 157 Hepatitis_C_virus_genotype_1a R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 16/6120 17/10654 0.0010898337844061428 0.002220615080943152 8.35528182751287e-4 356/929/8737/841/8797/8772/8717/8743/8837/8795/23643/7186/355/7099/353376/148022 16 Hepatitis_C_virus_genotype_1a R-HSA-180292 GAB1 signalosome 16/6120 17/10654 0.0010898337844061428 0.002220615080943152 8.35528182751287e-4 5295/7039/55824/2885/5829/1839/5290/2069/6714/1445/255324/5781/1956/2549/685/1950 16 Hepatitis_C_virus_genotype_1a R-HSA-450513 Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA 16/6120 17/10654 0.0010898337844061428 0.002220615080943152 8.35528182751287e-4 5393/23404/11340/9261/23016/118460/3842/7538/51010/56915/167227/7529/22894/51013/54464/54512 16 Hepatitis_C_virus_genotype_1a R-HSA-4655427 SUMOylation of DNA methylation proteins 16/6120 17/10654 0.0010898337844061428 0.002220615080943152 8.35528182751287e-4 1912/6045/80012/1911/1789/57332/1788/100532731/84733/7703/6015/8535/1786/7329/648/7341 16 Hepatitis_C_virus_genotype_1a R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 16/6120 17/10654 0.0010898337844061428 0.002220615080943152 8.35528182751287e-4 929/7314/257397/23098/23118/10454/6233/3656/7189/7311/23643/6885/7099/7316/353376/148022 16 Hepatitis_C_virus_genotype_1a R-HSA-5689603 UCH proteinases 74/6120 102/10654 0.0010967747535192088 0.0022315330482858362 8.396361749429351e-4 5689/221937/5682/4738/10445/143471/5705/5709/5695/11047/5711/7347/5683/5699/5702/7040/7345/3054/5696/5691/7314/5718/3607/5700/122706/5707/83444/171023/23198/86/4092/9861/7046/5698/5692/5713/5710/8473/9958/5719/6233/93973/8607/5706/580/5714/5688/5687/5708/5704/7048/7311/60/5694/7528/5684/5720/51377/5690/5717/9491/10197/7316/10213/8314/5715/283899/5701/4798/5685/5686/5716/5693/5721 74 Hepatitis_C_virus_genotype_1a R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 27/6120 32/10654 0.0011314765909307021 0.0022856475547454016 8.599972882356717e-4 51807/10381/7278/10576/7846/113457/10574/10693/79861/5204/10575/10376/84617/10382/7277/347733/10383/60/84790/22948/7280/10694/5203/112714/7203/908/6950 27 Hepatitis_C_virus_genotype_1a R-HSA-451326 Activation of kainate receptors upon glutamate binding 27/6120 32/10654 0.0011314765909307021 0.0022856475547454016 8.599972882356717e-4 2788/5331/2900/2782/1741/1739/2787/10681/2792/2785/2783/2784/801/2791/805/23236/2786/54331/59345/51764/94235/5330/55970/2793/1742/808/2790 27 Hepatitis_C_virus_genotype_1a R-HSA-5656169 Termination of translesion DNA synthesis 27/6120 32/10654 0.0011314765909307021 0.0022856475547454016 8.599972882356717e-4 5982/6117/10714/7314/6118/9636/11201/51455/5985/5984/6233/5424/124739/7706/5111/6119/5427/5429/9246/51426/7311/7318/5983/7316/5426/9100/5981 27 Hepatitis_C_virus_genotype_1a R-HSA-8941326 RUNX2 regulates bone development 27/6120 32/10654 0.0011314765909307021 0.0022856475547454016 8.599972882356717e-4 5925/9759/10413/4089/3549/25/5594/3280/100526737/10013/2737/865/6714/7525/10432/4091/1277/2736/367/860/5595/8841/23462/4086/4094/23314/25937 27 Hepatitis_C_virus_genotype_1a R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 27/6120 32/10654 0.0011314765909307021 0.0022856475547454016 8.599972882356717e-4 5295/5777/2534/30011/2885/973/933/6786/5336/7409/3710/118788/801/805/930/6850/4067/29760/695/6654/5293/27071/4690/640/10768/974/808 27 Hepatitis_C_virus_genotype_1a R-HSA-2173782 Binding and Uptake of Ligands by Scavenger Receptors 34/6120 42/10654 0.0011461343830693963 0.002311944892886765 8.698919193840461e-4 10525/3240/259/811/3043/949/9332/5648/6678/81035/1284/4481/348/78989/2495/8542/3250/55576/7184/1277/338/335/23166/2512/1282/284297/10808/1281/3320/4035/6288/948/213/1278 34 Hepatitis_C_virus_genotype_1a R-HSA-5218921 VEGFR2 mediated cell proliferation 19/6120 21/10654 0.0011485323769791604 0.0023134723593437375 8.704666436052586e-4 4893/5335/5579/5578/3845/3265/8877/5921/6714/5580/3791/3710/801/805/5170/5590/7422/10768/808 19 Hepatitis_C_virus_genotype_1a R-HSA-111932 CaMK IV-mediated phosphorylation of CREB 12/6120 12/10654 0.001284900838522196 0.002516264142105967 9.467690389110919e-4 817/814/818/801/805/3838/10645/84254/816/815/1385/808 12 Hepatitis_C_virus_genotype_1a R-HSA-170968 Frs2-mediated activation 12/6120 12/10654 0.001284900838522196 0.002516264142105967 9.467690389110919e-4 5605/1399/5594/4914/673/2889/7529/5595/5604/10818/4803/5906 12 Hepatitis_C_virus_genotype_1a R-HSA-1839130 Signaling by activated point mutants of FGFR3 12/6120 12/10654 0.001284900838522196 0.002516264142105967 9.467690389110919e-4 2250/2253/8823/8074/2249/2247/2246/8822/8817/2254/26281/2261 12 Hepatitis_C_virus_genotype_1a R-HSA-190873 Gap junction degradation 12/6120 12/10654 0.001284900838522196 0.002516264142105967 9.467690389110919e-4 71/1212/1785/2697/1759/4646/1601/1213/1211/1173/8218/60 12 Hepatitis_C_virus_genotype_1a R-HSA-2029481 FCGR activation 12/6120 12/10654 0.001284900838522196 0.002516264142105967 9.467690389110919e-4 2268/2534/6714/7525/2214/2209/6850/4067/919/3055/917/2212 12 Hepatitis_C_virus_genotype_1a R-HSA-2033514 FGFR3 mutant receptor activation 12/6120 12/10654 0.001284900838522196 0.002516264142105967 9.467690389110919e-4 2250/2253/8823/8074/2249/2247/2246/8822/8817/2254/26281/2261 12 Hepatitis_C_virus_genotype_1a R-HSA-210990 PECAM1 interactions 12/6120 12/10654 0.001284900838522196 0.002516264142105967 9.467690389110919e-4 5777/5335/5175/2534/3690/3635/6714/7525/3685/3932/5781/4067 12 Hepatitis_C_virus_genotype_1a R-HSA-2197563 NOTCH2 intracellular domain regulates transcription 12/6120 12/10654 0.001284900838522196 0.002516264142105967 9.467690389110919e-4 4853/9794/388585/55534/3280/84441/3002/10046/2208/2033/1385/3516 12 Hepatitis_C_virus_genotype_1a R-HSA-3371511 HSF1 activation 12/6120 12/10654 0.001284900838522196 0.002516264142105967 9.467690389110919e-4 7531/1915/6117/6118/10013/3297/6119/3281/3326/10728/7415/3320 12 Hepatitis_C_virus_genotype_1a R-HSA-381033 ATF6 (ATF6-alpha) activates chaperones 12/6120 12/10654 0.001284900838522196 0.002516264142105967 9.467690389110919e-4 811/3309/4801/8720/468/7184/7494/4800/22926/4802/1649/51360 12 Hepatitis_C_virus_genotype_1a R-HSA-389359 CD28 dependent Vav1 pathway 12/6120 12/10654 0.001284900838522196 0.002516264142105967 9.467690389110919e-4 941/2534/2885/5062/5879/7409/3932/940/5063/998/5058/942 12 Hepatitis_C_virus_genotype_1a R-HSA-417957 P2Y receptors 12/6120 12/10654 0.001284900838522196 0.002516264142105967 9.467690389110919e-4 10161/64805/2840/5028/5029/53829/27334/9934/5032/5031/5030/2846 12 Hepatitis_C_virus_genotype_1a R-HSA-430116 GP1b-IX-V activation signalling 12/6120 12/10654 0.001284900838522196 0.002516264142105967 9.467690389110919e-4 5295/5894/7534/6714/2814/2316/1277/7450/2812/2811/2815/1278 12 Hepatitis_C_virus_genotype_1a R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 12/6120 12/10654 0.001284900838522196 0.002516264142105967 9.467690389110919e-4 834/55367/472/8738/7157/839/317/843/8626/7161/835/58484 12 Hepatitis_C_virus_genotype_1a R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 12/6120 12/10654 0.001284900838522196 0.002516264142105967 9.467690389110919e-4 7159/23368/8797/7157/8626/7161/8795/8793/3486/355/8794/124446 12 Hepatitis_C_virus_genotype_1a R-HSA-8866427 VLDLR internalisation and degradation 12/6120 12/10654 0.001284900838522196 0.002516264142105967 9.467690389110919e-4 163/10062/161/7436/1213/1211/1175/29116/1173/160/255738/7376 12 Hepatitis_C_virus_genotype_1a R-HSA-8984722 Interleukin-35 Signalling 12/6120 12/10654 0.001284900838522196 0.002516264142105967 9.467690389110919e-4 3717/3572/10148/3592/7297/6775/3595/821/6774/6772/3716/9466 12 Hepatitis_C_virus_genotype_1a R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 12/6120 12/10654 0.001284900838522196 0.002516264142105967 9.467690389110919e-4 7187/7314/29110/3661/6233/10010/3665/7098/7311/9641/7316/148022 12 Hepatitis_C_virus_genotype_1a R-HSA-9020558 Interleukin-2 signaling 12/6120 12/10654 0.001284900838522196 0.002516264142105967 9.467690389110919e-4 6776/3558/3718/3932/6777/6464/6850/3716/2185/3561/3560/3559 12 Hepatitis_C_virus_genotype_1a R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 12/6120 12/10654 0.001284900838522196 0.002516264142105967 9.467690389110919e-4 5295/5291/3717/2056/8660/5290/5294/2057/4067/5293/2549/23533 12 Hepatitis_C_virus_genotype_1a R-HSA-1855204 Synthesis of IP3 and IP4 in the cytosol 24/6120 28/10654 0.0013858703397657715 0.0027102318711092065 0.001019751297528212 5335/5331/80271/51196/3635/5336/113026/5332/801/805/3633/8867/89869/3636/23236/84812/9651/5330/5333/3705/5728/23007/808/4952 24 Hepatitis_C_virus_genotype_1a R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 48/6120 63/10654 0.0014771024453282182 0.002884646049740703 0.0010853763412238255 4790/5435/4792/3428/1387/22954/1660/3551/7314/11035/8737/29110/81844/8517/6778/51428/5970/3661/6233/11128/4791/9533/3665/5434/23220/7098/9208/5591/7311/171568/10621/2547/1147/170506/5440/6737/1499/7520/147945/5441/51082/4615/7316/55703/4793/5437/2033/148022 48 Hepatitis_C_virus_genotype_1a R-HSA-8878171 Transcriptional regulation by RUNX1 160/6120 239/10654 0.0014814458890914039 0.0028891268376471362 0.001087062281578318 1912/9070/5689/1437/5579/5682/1459/6045/9021/5929/27327/80012/1460/143471/5705/5709/5695/28996/1457/1911/6603/10413/5711/1387/3558/5683/10138/57332/5699/8312/5702/192669/83737/5371/57492/6688/4343/5696/5691/7314/55170/5718/84661/25/4773/8861/5700/122706/5707/23198/100532731/86/100506658/865/7082/23309/51412/6714/2099/9861/8850/84733/5588/6604/8289/5698/5692/5713/6602/595/5710/3458/896/5719/6233/26523/5781/1493/23429/55193/6015/1514/55904/6595/3562/6597/6929/8535/3674/1378/6938/3958/5706/6599/200845/4331/57678/2623/5714/5688/5687/5708/4602/5704/7311/7161/860/58508/25942/648/5694/6601/23466/4297/4004/27161/894/5684/5720/902/11091/640/8085/5690/2625/57690/5717/9491/4005/6598/10197/192670/5196/7316/10213/5079/10398/122809/5715/5701/5685/5686/2033/1021/6605/50943/3065/861/23112/9757/5716/2811/9739/3276/3977/3559/7057/1022/5693/5721 160 Hepatitis_C_virus_genotype_1a R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 31/6120 38/10654 0.0014948787354498734 0.0029112969847849743 0.0010954040166716143 7039/51741/2064/5308/4609/1387/7913/7022/8089/3815/348/2099/3329/284252/10765/7020/4869/4839/79047/10370/7329/29028/1956/7528/4605/4435/7021/7422/1026/7341/2033 31 Hepatitis_C_virus_genotype_1a R-HSA-203927 MicroRNA (miRNA) biogenesis 21/6120 24/10654 0.0016390649884797757 0.0031745626837314336 0.0011944603154913345 5431/5435/5433/5439/192669/29102/5438/54487/57510/26523/23405/5434/5436/5901/5432/27161/5440/5430/5441/192670/5437 21 Hepatitis_C_virus_genotype_1a R-HSA-449836 Other interleukin signaling 21/6120 24/10654 0.0016390649884797757 0.0031745626837314336 0.0011944603154913345 6804/5657/5803/1435/836/282618/6382/9235/3588/6810/6844/6809/7297/6616/920/1440/163702/146433/3716/1436/1441 21 Hepatitis_C_virus_genotype_1a R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 21/6120 24/10654 0.0016390649884797757 0.0031745626837314336 0.0011944603154913345 5579/10811/5578/6280/1432/5879/5594/5880/5580/1535/5600/30849/4688/5590/653361/6279/5595/27035/5289/5300/1536 21 Hepatitis_C_virus_genotype_1a R-HSA-933542 TRAF6 mediated NF-kB activation 21/6120 24/10654 0.0016390649884797757 0.0031745626837314336 0.0011944603154913345 4790/4792/177/64135/3551/6283/4214/8517/5970/23586/4791/351/7706/7189/1147/7186/57506/4793/3146/6288/6285 21 Hepatitis_C_virus_genotype_1a R-HSA-1433559 Regulation of KIT signaling 15/6120 16/10654 0.0017955538369250372 0.00345864878424085 0.001301350494406412 5777/5578/2534/2885/3815/9306/6714/7525/3932/10019/8651/4067/6654/867/4254 15 Hepatitis_C_virus_genotype_1a R-HSA-418038 Nucleotide-like (purinergic) receptors 15/6120 16/10654 0.0017955538369250372 0.00345864878424085 0.001301350494406412 10161/64805/2840/5028/5029/53829/27334/134/9934/135/5032/140/5031/5030/2846 15 Hepatitis_C_virus_genotype_1a R-HSA-5654219 Phospholipase C-mediated cascade: FGFR1 15/6120 16/10654 0.0017955538369250372 0.00345864878424085 0.001301350494406412 2250/5335/2253/8074/2260/2249/2248/2247/2246/2251/8822/2254/26281/2255/27006 15 Hepatitis_C_virus_genotype_1a R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 15/6120 16/10654 0.0017955538369250372 0.00345864878424085 0.001301350494406412 929/7314/257397/23118/10454/6233/3656/7189/7311/23643/6885/7099/7316/353376/148022 15 Hepatitis_C_virus_genotype_1a R-HSA-5693537 Resolution of D-Loop Structures 28/6120 34/10654 0.0019367063331588803 0.0037254514730614206 0.0014017376203232222 83990/5892/9156/1763/7486/472/80198/4683/672/348654/5888/116028/7517/84464/80010/580/641/10524/5889/79728/146956/10111/675/79008/10635/5932/7156/5890 28 Hepatitis_C_virus_genotype_1a R-HSA-373755 Semaphorin interactions 49/6120 65/10654 0.001973844732416003 0.003789042250971178 0.0014256642736016976 5361/7305/2909/388/2064/5788/8829/3688/54209/23365/79784/2534/9475/1808/4628/6093/10507/5362/5062/5879/1400/23396/1072/7094/389/10371/3672/2932/55558/10154/10627/4233/5063/3326/387/5058/1020/3984/4627/3985/10398/4637/3320/91584/56896/103910/8851/6237/2242 49 Hepatitis_C_virus_genotype_1a R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 43/6120 56/10654 0.0019778263097267996 0.003789042250971178 0.0014256642736016976 79718/5469/1387/6907/2101/84808/10499/1386/3054/7019/814/23408/5465/64784/2747/4208/6604/55902/6742/801/133522/64216/805/5442/23410/4209/2553/2551/6648/211/23373/2746/8841/200186/9611/23409/54205/6256/10498/1385/808/8648/10891 43 Hepatitis_C_virus_genotype_1a R-HSA-429914 Deadenylation-dependent mRNA decay 43/6120 56/10654 0.0019778263097267996 0.003789042250971178 0.0014256642736016976 5393/23404/26986/28960/25904/1973/55571/11340/57472/85456/29883/80349/51690/11157/1981/1977/23016/118460/9924/23644/5073/27258/4850/57819/246175/4848/23019/23658/1975/51010/56915/1974/167227/22894/1656/27257/4849/25804/9337/51013/9775/54464/54512 43 Hepatitis_C_virus_genotype_1a R-HSA-1059683 Interleukin-6 signaling 11/6120 11/10654 0.002238533250023202 0.0041695269254064925 0.0015688253605112897 9021/3717/3569/3572/3570/7297/5781/6774/6772/3716/867 11 Hepatitis_C_virus_genotype_1a R-HSA-1839122 Signaling by activated point mutants of FGFR1 11/6120 11/10654 0.002238533250023202 0.0041695269254064925 0.0015688253605112897 2250/2253/8074/2260/2249/2247/2246/2251/8822/2254/26281 11 Hepatitis_C_virus_genotype_1a R-HSA-193692 Regulated proteolysis of p75NTR 11/6120 11/10654 0.002238533250023202 0.0041695269254064925 0.0015688253605112897 4790/23385/6868/5970/5664/5663/7189/83464/55851/51107/4804 11 Hepatitis_C_virus_genotype_1a R-HSA-196025 Formation of annular gap junctions 11/6120 11/10654 0.002238533250023202 0.0041695269254064925 0.0015688253605112897 71/1212/1785/2697/1759/1601/1213/1211/1173/8218/60 11 Hepatitis_C_virus_genotype_1a R-HSA-2025928 Calcineurin activates NFAT 11/6120 11/10654 0.002238533250023202 0.0041695269254064925 0.0015688253605112897 5530/4773/2280/5478/801/805/4772/4775/5532/5534/808 11 Hepatitis_C_virus_genotype_1a R-HSA-2514853 Condensation of Prometaphase Chromosomes 11/6120 11/10654 0.002238533250023202 0.0041695269254064925 0.0015688253605112897 1459/1460/1457/64151/10051/983/23397/9133/891/10592/9918 11 Hepatitis_C_virus_genotype_1a R-HSA-3371378 Regulation by c-FLIP 11/6120 11/10654 0.002238533250023202 0.0041695269254064925 0.0015688253605112897 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355 11 Hepatitis_C_virus_genotype_1a R-HSA-400451 Free fatty acids regulate insulin secretion 11/6120 11/10654 0.002238533250023202 0.0041695269254064925 0.0015688253605112897 5331/2769/2776/2181/2182/2864/23236/5330/2767/948/9630 11 Hepatitis_C_virus_genotype_1a R-HSA-446107 Type I hemidesmosome assembly 11/6120 11/10654 0.002238533250023202 0.0041695269254064925 0.0015688253605112897 3852/3861/3655/3918/5339/3909/3691/1308/667/3914/977 11 Hepatitis_C_virus_genotype_1a R-HSA-4755510 SUMOylation of immune response proteins 11/6120 11/10654 0.002238533250023202 0.0041695269254064925 0.0015688253605112897 4792/6612/51588/8517/5970/4791/10210/7329/9641/7341/10401 11 Hepatitis_C_virus_genotype_1a R-HSA-5218900 CASP8 activity is inhibited 11/6120 11/10654 0.002238533250023202 0.0041695269254064925 0.0015688253605112897 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355 11 Hepatitis_C_virus_genotype_1a R-HSA-5603041 IRAK4 deficiency (TLR2/4) 11/6120 11/10654 0.002238533250023202 0.0041695269254064925 0.0015688253605112897 10333/929/51135/7096/695/23643/7099/4615/114609/948/7097 11 Hepatitis_C_virus_genotype_1a R-HSA-5655291 Signaling by FGFR4 in disease 11/6120 11/10654 0.002238533250023202 0.0041695269254064925 0.0015688253605112897 5295/4893/5335/2264/2885/3845/3265/5290/6654/2549/10818 11 Hepatitis_C_virus_genotype_1a R-HSA-69416 Dimerization of procaspase-8 11/6120 11/10654 0.002238533250023202 0.0041695269254064925 0.0015688253605112897 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355 11 Hepatitis_C_virus_genotype_1a R-HSA-8851805 MET activates RAS signaling 11/6120 11/10654 0.002238533250023202 0.0041695269254064925 0.0015688253605112897 4893/3082/2885/3845/3265/57610/6464/4233/6654/10048/200958 11 Hepatitis_C_virus_genotype_1a R-HSA-8875555 MET activates RAP1 and RAC1 11/6120 11/10654 0.002238533250023202 0.0041695269254064925 0.0015688253605112897 5908/3082/2885/1399/5879/85440/4233/2889/2549/1398/5906 11 Hepatitis_C_virus_genotype_1a R-HSA-8934903 Receptor Mediated Mitophagy 11/6120 11/10654 0.002238533250023202 0.0041695269254064925 0.0015688253605112897 1459/9140/1460/9474/1457/84557/139341/192111/6714/8408/81631 11 Hepatitis_C_virus_genotype_1a R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 11/6120 11/10654 0.002238533250023202 0.0041695269254064925 0.0015688253605112897 7314/257397/23118/10454/6233/7098/7189/7311/6885/7316/148022 11 Hepatitis_C_virus_genotype_1a R-HSA-9020956 Interleukin-27 signaling 11/6120 11/10654 0.002238533250023202 0.0041695269254064925 0.0015688253605112897 3717/3572/10148/7297/821/6774/6772/9244/3716/246778/9466 11 Hepatitis_C_virus_genotype_1a R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 11/6120 11/10654 0.002238533250023202 0.0041695269254064925 0.0015688253605112897 627/4893/2885/3845/3265/4909/5781/6654/4915/10817/10818 11 Hepatitis_C_virus_genotype_1a R-HSA-9614399 Regulation of localization of FOXO transcription factors 11/6120 11/10654 0.002238533250023202 0.0041695269254064925 0.0015688253605112897 2308/10971/2810/7534/10000/7532/4303/208/7529/2309/207 11 Hepatitis_C_virus_genotype_1a R-HSA-8963899 Plasma lipoprotein remodeling 25/6120 30/10654 0.0024841677647374255 0.004620945314353258 0.0017386759525450115 3931/4023/1071/27329/9619/8720/344/345/51129/84699/5360/9388/348/336/338328/116519/319/338/335/3990/26291/5045/91289/51360/213 25 Hepatitis_C_virus_genotype_1a R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 20/6120 23/10654 0.0025222572458085102 0.004673301861484887 0.0017583756164153664 5431/5435/5433/5439/51497/5438/6829/25920/2963/5434/5436/2962/5432/22916/5440/5430/5441/4686/5437/6827 20 Hepatitis_C_virus_genotype_1a R-HSA-373753 Nephrin family interactions 20/6120 23/10654 0.0025222572458085102 0.004673301861484887 0.0017583756164153664 5295/6711/5291/2534/87/8976/6709/8826/8440/5290/9863/8573/81/23607/4868/4690/7827/89/88/5296 20 Hepatitis_C_virus_genotype_1a R-HSA-438066 Unblocking of NMDA receptors, glutamate binding and activation 20/6120 23/10654 0.0025222572458085102 0.004673301861484887 0.0017583756164153664 817/1741/1739/1740/818/57554/2902/2906/801/2891/4747/805/2904/2905/816/815/2903/1742/88/808 20 Hepatitis_C_virus_genotype_1a R-HSA-167169 HIV Transcription Elongation 36/6120 46/10654 0.0025561676970214564 0.004717534624084102 0.0017750186267550486 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/4686/5437/6827/2968/1022/8178 36 Hepatitis_C_virus_genotype_1a R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 36/6120 46/10654 0.0025561676970214564 0.004717534624084102 0.0017750186267550486 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/4686/5437/6827/2968/1022/8178 36 Hepatitis_C_virus_genotype_1a R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 36/6120 46/10654 0.0025561676970214564 0.004717534624084102 0.0017750186267550486 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/4686/5437/6827/2968/1022/8178 36 Hepatitis_C_virus_genotype_1a R-HSA-112382 Formation of RNA Pol II elongation complex 46/6120 61/10654 0.0026619267040074238 0.004899891191449696 0.0018436320720348243 5431/5435/5433/2965/5439/2967/11198/904/51497/80349/404672/5438/2068/1025/23168/6829/123169/25920/85403/2963/5434/5436/9646/79577/4331/2966/2962/8812/2071/5432/22916/55840/6917/5440/902/6830/5430/6749/5441/4686/54623/5437/6827/2968/1022/8178 46 Hepatitis_C_virus_genotype_1a R-HSA-75955 RNA Polymerase II Transcription Elongation 46/6120 61/10654 0.0026619267040074238 0.004899891191449696 0.0018436320720348243 5431/5435/5433/2965/5439/2967/11198/904/51497/80349/404672/5438/2068/1025/23168/6829/123169/25920/85403/2963/5434/5436/9646/79577/4331/2966/2962/8812/2071/5432/22916/55840/6917/5440/902/6830/5430/6749/5441/4686/54623/5437/6827/2968/1022/8178 46 Hepatitis_delta_virus_genotype_I R-HSA-5696394 DNA Damage Recognition in GG-NER 33/362 38/10654 3.404584033523153e-44 3.166263151176532e-41 2.0319991021132921e-41 9318/283899/29844/4798/79913/93973/60/8533/86/8607/5887/1642/54617/10920/8450/9978/142/125476/10987/83444/64708/1069/5886/50813/1643/7508/54891/10445/51138/8451/2873/10980/7528 33 Hepatitis_delta_virus_genotype_I R-HSA-5696398 Nucleotide Excision Repair 48/362 111/10654 1.4948912738422562e-41 6.951244423366491e-39 4.4610702750976795e-39 9318/283899/29844/4798/5437/79913/5441/5434/5440/93973/60/8533/86/5438/8607/5887/1642/54617/5431/10920/2033/8450/5435/9978/142/5433/125476/5439/10987/5430/83444/5432/64708/1069/91603/5436/5886/50813/5111/1643/7508/54891/10445/51138/8451/2873/10980/7528 48 Hepatitis_delta_virus_genotype_I R-HSA-9018519 Estrogen-dependent gene expression 53/362 150/10654 2.4285090663582472e-40 7.528378105710566e-38 4.831454879386407e-38 3727/27327/7391/2353/8850/27161/3725/10524/2958/1387/10499/3838/5437/5441/5434/5440/1386/6908/3169/192670/5438/4343/5431/2033/4435/5435/3276/5433/865/8312/7031/26523/8204/5439/1655/192669/3065/8202/5430/5432/8648/861/5436/5451/6667/23112/2625/2099/57690/2957/10498/4609/7528 53 Hepatitis_delta_virus_genotype_I R-HSA-8939211 ESR-mediated signaling 56/362 223/10654 1.3389722609525465e-33 3.113110506714671e-31 1.9978875577897206e-31 3727/27327/1385/7391/2353/8850/27161/3725/10524/2958/1387/10499/3838/5437/5441/5434/5440/1386/6908/3169/192670/5438/4343/5431/2033/2100/4435/2309/5435/3276/5433/865/8312/7031/26523/8204/5439/1655/192669/3065/8202/5430/5432/8648/861/5436/5451/6667/23112/2625/2099/57690/2957/10498/4609/7528 56 Hepatitis_delta_virus_genotype_I R-HSA-9006931 Signaling by Nuclear Receptors 63/362 299/10654 5.5950570420562384e-33 1.0406806098224603e-30 6.678731248096604e-31 3727/27327/1385/7391/2353/8850/27161/5915/3725/10524/2958/1387/10499/3838/5437/5441/5434/5440/1386/6908/6720/8841/5914/3169/192670/5438/4343/5431/2033/2100/4435/2309/5435/3276/5433/9611/865/8312/7031/26523/8204/5439/1655/192669/3065/8202/5430/5432/8648/861/6256/5436/5451/6667/23112/7376/2625/2099/57690/2957/10498/4609/7528 63 Hepatitis_delta_virus_genotype_I R-HSA-73894 DNA Repair 65/362 334/10654 7.456000950721882e-32 1.1556801473618918e-29 7.416758840454925e-30 672/9318/283899/1017/7158/7014/7013/6047/22976/29844/10524/4798/4683/3838/5437/79913/5441/5434/5440/93973/7706/60/8533/86/5438/8607/5887/1642/54617/5431/10920/5591/2033/8450/5435/9978/142/5433/125476/2070/2547/5439/10987/5430/7157/83444/5432/64708/1069/8314/91603/5436/5886/50813/5111/1643/7508/54891/10445/7520/51138/8451/2873/10980/7528 65 Hepatitis_delta_virus_genotype_I R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 47/362 182/10654 7.813234475111627e-29 1.0380440088362591e-26 6.66181044720044e-27 672/115426/7158/7020/367/1387/10499/6670/1616/5914/25942/7068/5465/2033/23512/648/7022/7021/142/9971/1029/7703/8204/1655/7428/3066/3065/7157/5970/4792/3190/9759/8648/8856/1069/6256/6045/6790/5371/5111/7376/2099/10891/7508/6015/4193/4869 47 Hepatitis_delta_virus_genotype_I R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 34/362 84/10654 1.9648492359882079e-28 2.2841372368362915e-26 1.4658809431648864e-26 9318/283899/29844/4798/79913/93973/60/8533/86/8607/5887/1642/54617/10920/8450/9978/142/125476/10987/83444/64708/1069/5886/50813/5111/1643/7508/54891/10445/51138/8451/2873/10980/7528 34 Hepatitis_delta_virus_genotype_I R-HSA-2990846 SUMOylation 47/362 188/10654 3.771742474269163e-28 3.897467223411468e-26 2.501260798725866e-26 672/115426/7158/7020/367/1387/10499/6670/1616/5914/25942/7068/5465/2033/23512/648/7022/7021/142/9971/1029/7703/8204/1655/7428/3066/3065/7157/5970/4792/3190/9759/8648/8856/1069/6256/6045/6790/5371/5111/7376/2099/10891/7508/6015/4193/4869 47 Hepatitis_delta_virus_genotype_I R-HSA-5617472 Activation of anterior HOX genes in hindbrain development during early embryogenesis 39/362 122/10654 6.6768840092574305e-28 5.645001935099464e-26 3.6227686442573805e-26 5931/9070/5928/5915/3725/22976/1387/58508/5437/23054/5441/5434/5440/8841/5914/5438/8726/5431/11091/7403/2033/23512/5435/5080/5433/9611/10664/7703/5439/2146/8202/5430/5432/8085/6256/5436/3233/7528/5929 39 Hepatitis_delta_virus_genotype_I R-HSA-5619507 Activation of HOX genes during differentiation 39/362 122/10654 6.6768840092574305e-28 5.645001935099464e-26 3.6227686442573805e-26 5931/9070/5928/5915/3725/22976/1387/58508/5437/23054/5441/5434/5440/8841/5914/5438/8726/5431/11091/7403/2033/23512/5435/5080/5433/9611/10664/7703/5439/2146/8202/5430/5432/8085/6256/5436/3233/7528/5929 39 Hepatitis_delta_virus_genotype_I R-HSA-3700989 Transcriptional Regulation by TP53 62/362 365/10654 6.4407211458880665e-27 4.9915588880632515e-25 3.203411306770643e-25 2475/672/27327/5931/2353/1017/604/1647/1460/5928/27161/3725/10524/1387/4683/5437/5441/5434/5440/1386/1616/6908/10419/192670/5438/581/4343/5431/9337/2033/5435/3276/5433/6829/1029/7027/26523/1459/5439/192669/3066/3065/5430/7157/1457/9219/5432/57521/5436/6790/5371/23112/5111/10919/57690/1643/8148/10498/7832/4193/4869/64223 62 Hepatitis_delta_virus_genotype_I R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 27/362 54/10654 7.111883412739438e-26 5.087731979882828e-24 3.26513189880426e-24 9318/5437/5441/5434/5440/8533/5438/1642/5431/10920/2033/8450/5435/9978/5433/5439/10987/5430/5432/64708/91603/5436/50813/51138/8451/2873/10980 27 Hepatitis_delta_virus_genotype_I R-HSA-8878171 Transcriptional regulation by RUNX1 49/362 239/10654 4.138007037666244e-25 2.748818960735434e-23 1.764097737110346e-23 55904/5715/27327/2811/8850/9070/1460/84661/27161/1387/58508/161882/192670/25942/86/9739/4343/11091/10138/2033/648/3276/865/6929/8312/26523/1459/7057/192669/3065/1457/861/8085/23429/4297/3674/6045/2623/5371/23112/23309/2625/2099/57690/23067/6015/55170/5929/9757 49 Hepatitis_delta_virus_genotype_I R-HSA-3247509 Chromatin modifying enzymes 52/362 274/10654 6.040335594473576e-25 3.5109450642877664e-23 2.2532041329384983e-23 55904/5931/8850/9070/84661/5928/10524/1387/58508/10499/57634/1386/8295/10419/8841/60/86/8607/9739/8726/11091/4790/7403/2033/23512/3054/8819/10902/3276/54556/9611/6944/6187/8473/2146/3066/3065/10856/5970/79084/9219/8648/8085/4297/10919/10498/23067/10445/2122/55170/5929/9757 52 Hepatitis_delta_virus_genotype_I R-HSA-4839726 Chromatin organization 52/362 274/10654 6.040335594473576e-25 3.5109450642877664e-23 2.2532041329384983e-23 55904/5931/8850/9070/84661/5928/10524/1387/58508/10499/57634/1386/8295/10419/8841/60/86/8607/9739/8726/11091/4790/7403/2033/23512/3054/8819/10902/3276/54556/9611/6944/6187/8473/2146/3066/3065/10856/5970/79084/9219/8648/8085/4297/10919/10498/23067/10445/2122/55170/5929/9757 52 Hepatitis_delta_virus_genotype_I R-HSA-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function 32/362 97/10654 1.53744582284141e-23 8.410733030838301e-22 5.3977200096042065e-22 55904/27327/2811/8850/9070/84661/58508/161882/192670/25942/9739/4343/11091/2033/3276/865/26523/7057/192669/3065/861/8085/4297/3674/2623/23112/23309/57690/23067/55170/5929/9757 32 Hepatitis_delta_virus_genotype_I R-HSA-5688426 Deubiquitination 52/362 297/10654 3.093664205885016e-23 1.5983931730405916e-21 1.0257939208987158e-21 4089/5715/672/409/283899/4086/8850/367/29844/4798/79913/4287/93973/6502/8295/4088/7706/60/3607/86/8607/64750/221937/5887/54617/2033/408/3054/1540/8312/79155/125476/7321/8473/51377/7157/83444/4792/8314/4087/55252/171023/5886/2625/2099/1643/4303/4609/54891/10445/4193/7528 52 Hepatitis_delta_virus_genotype_I R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 28/362 79/10654 1.039493078658376e-21 5.088045069222577e-20 3.2653328288049814e-20 9318/5437/5441/5434/5440/8533/5438/1642/5431/10920/2033/8450/5435/9978/5433/5439/10987/5430/5432/64708/91603/5436/50813/5111/51138/8451/2873/10980 28 Hepatitis_delta_virus_genotype_I R-HSA-5663202 Diseases of signal transduction 56/362 377/10654 2.231727703291577e-21 1.0377533820305833e-19 6.659945304033286e-20 2475/4089/10014/5715/8454/6500/409/1385/2308/8850/1387/5437/2064/5441/5434/5440/6199/4088/8841/60/2247/5438/5431/2335/2033/6776/408/2100/2309/5435/1499/55294/9978/5433/9611/8312/5439/3066/3065/4851/5430/2280/5432/9759/5894/4087/3674/5436/11140/5245/6772/2099/4303/4609/4193/64223 56 Hepatitis_delta_virus_genotype_I R-HSA-6807070 PTEN Regulation 35/362 140/10654 3.702034510219391e-21 1.6394724259543017e-19 1.0521571765886689e-19 2475/10014/5715/27327/5931/1460/5928/27161/3725/1386/8841/192670/4343/8726/23512/648/26523/1459/192669/2146/3066/3065/7157/1457/9219/57521/10273/4734/6045/5371/23112/57690/2122/6015/64223 35 Hepatitis_delta_virus_genotype_I R-HSA-203927 MicroRNA (miRNA) biogenesis 17/362 24/10654 2.0644727877611077e-20 8.727089511899227e-19 5.6007467495719995e-19 27161/5437/5441/5434/5440/192670/5438/5431/5435/54487/5433/26523/5439/192669/5430/5432/5436 17 Hepatitis_delta_virus_genotype_I R-HSA-1257604 PIP3 activates AKT signaling 45/362 264/10654 1.0582891392089593e-19 4.279169128105792e-18 2.7462239905330886e-18 2475/10014/5715/27327/1385/5931/2308/1460/5928/27161/3725/2064/1386/6199/8841/2247/192670/4343/8726/23512/648/2100/2309/26523/1459/192669/2146/3066/3065/7157/1457/9219/57521/10273/4734/6045/5371/23112/2099/57690/4303/2122/6015/4193/64223 45 Hepatitis_delta_virus_genotype_I R-HSA-72163 mRNA Splicing - Major Pathway 36/362 183/10654 4.9701620041480556e-18 1.9259377766073716e-16 1.2360008141894505e-16 10921/3178/6637/10236/5437/6635/5441/6634/5434/5440/6633/9775/3192/10189/5438/6632/5431/5435/6625/5433/5439/1655/9343/1660/4116/5430/3190/5432/5436/2521/11100/55339/6628/6636/1994/8106 36 Hepatitis_delta_virus_genotype_I R-HSA-9006925 Intracellular signaling by second messengers 46/362 305/10654 6.340104259279488e-18 2.3585187844519695e-16 1.5136164694785134e-16 2475/10014/5715/27327/1385/5931/2308/1460/5928/27161/3725/3838/2064/1386/6199/8841/2247/192670/4343/8726/23512/648/2100/2309/26523/1459/192669/2146/3066/3065/7157/1457/9219/57521/10273/4734/6045/5371/23112/2099/57690/4303/2122/6015/4193/64223 46 Hepatitis_delta_virus_genotype_I R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 41/362 244/10654 8.680706522145744e-18 3.1050219483059776e-16 1.9926965984034968e-16 10921/3178/6637/10236/9984/5437/6635/5441/6634/5434/5440/6633/26097/9775/3192/10189/5438/6632/5431/5435/6625/5433/10482/5439/1655/9343/1660/4116/5430/3190/5432/56339/5436/2521/11100/57721/55339/6628/6636/1994/8106 41 Hepatitis_delta_virus_genotype_I R-HSA-72172 mRNA Splicing 36/362 191/10654 2.1417951359519224e-17 7.377294357167733e-16 4.734494511051617e-16 10921/3178/6637/10236/5437/6635/5441/6634/5434/5440/6633/9775/3192/10189/5438/6632/5431/5435/6625/5433/5439/1655/9343/1660/4116/5430/3190/5432/5436/2521/11100/55339/6628/6636/1994/8106 36 Hepatitis_delta_virus_genotype_I R-HSA-72165 mRNA Splicing - Minor Pathway 20/362 52/10654 1.1679780525360497e-16 3.879355674494737e-15 2.4896374277742112e-15 6637/5437/6635/5441/6634/5434/5440/6633/5438/6632/5431/5435/5433/5439/9343/5430/5432/5436/6628/6636 20 Hepatitis_delta_virus_genotype_I R-HSA-2559583 Cellular Senescence 35/362 195/10654 3.027657079524634e-16 9.709383048130724e-15 6.231149052959954e-15 27327/5931/2353/1017/5925/7014/7013/5928/3725/10524/4683/57634/192670/4343/8726/4790/23512/648/1029/7027/26523/7321/192669/2146/7157/5970/6045/6667/23112/10919/57690/1870/6015/4193/1871 35 Hepatitis_delta_virus_genotype_I R-HSA-8851708 Signaling by FGFR2 IIIa TM 13/362 19/10654 1.4687870303824765e-15 4.5532397941856774e-14 2.922113144655664e-14 5437/5441/5434/5440/2247/5438/5431/5435/5433/5439/5430/5432/5436 13 Hepatitis_delta_virus_genotype_I R-HSA-8943724 Regulation of PTEN gene transcription 20/362 61/10654 4.368977754205991e-15 1.3106933262617972e-13 8.411580260220024e-14 2475/10014/5931/5928/3725/1386/8841/8726/23512/648/2146/3066/3065/7157/9219/57521/6045/2122/6015/64223 20 Hepatitis_delta_virus_genotype_I R-HSA-8951664 Neddylation 36/362 234/10654 1.6964252382017606e-14 4.930235848523866e-13 3.164056283093415e-13 5715/8454/9318/6500/5931/25793/6502/8533/55832/1642/10920/11091/8452/23363/8450/55294/50717/9978/84727/7321/10987/7428/8453/9040/64708/80176/50813/8139/9820/1643/51138/8451/2873/10980/54876/5929 36 Hepatitis_delta_virus_genotype_I R-HSA-2559585 Oncogene Induced Senescence 15/362 33/10654 4.1466346346563415e-14 1.134226532420705e-12 7.279076897368872e-13 27327/5925/192670/4343/1029/7027/26523/192669/7157/6667/23112/57690/1870/4193/1871 15 Hepatitis_delta_virus_genotype_I R-HSA-9022692 Regulation of MECP2 expression and activity 15/362 33/10654 4.1466346346563415e-14 1.134226532420705e-12 7.279076897368872e-13 27327/1385/27161/8841/192670/25942/4343/9611/26523/192669/3066/3065/4204/23112/57690 15 Hepatitis_delta_virus_genotype_I R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 13/362 23/10654 5.473070300060155e-14 1.4542729654445555e-12 9.333025143260474e-13 5437/5441/5434/5440/5438/5431/5435/5433/6829/5439/5430/5432/5436 13 Hepatitis_delta_virus_genotype_I R-HSA-3214841 PKMTs methylate histone lysines 20/362 71/10654 1.1564851133055868e-13 2.9875865427060993e-12 1.917330582585578e-12 55904/5931/9070/84661/5928/58508/9739/8726/11091/4790/23512/2146/5970/8085/4297/10919/23067/2122/5929/9757 20 Hepatitis_delta_virus_genotype_I R-HSA-8953750 Transcriptional Regulation by E2F6 15/362 35/10654 1.2204091521550382e-13 3.0675148959572583e-12 1.96862585852605e-12 672/5931/5928/4149/8726/10138/23512/648/7027/7703/2146/23429/6045/10919/6015 15 Hepatitis_delta_virus_genotype_I R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 19/362 65/10654 2.290127963977043e-13 5.324547516246625e-12 3.4171119883552196e-12 5437/5441/5434/5440/5438/1642/5431/2033/8450/5435/9978/5433/5439/5430/5432/91603/5436/5111/8451 19 Hepatitis_delta_virus_genotype_I R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 19/362 65/10654 2.290127963977043e-13 5.324547516246625e-12 3.4171119883552196e-12 672/2353/3725/5437/5441/5434/5440/1386/5438/5431/5435/5433/6829/5439/5430/7157/5432/5436/1643 19 Hepatitis_delta_virus_genotype_I R-HSA-9614085 FOXO-mediated transcription 19/362 65/10654 2.290127963977043e-13 5.324547516246625e-12 3.4171119883552196e-12 4089/2308/8850/604/1647/1387/4287/6720/23411/4088/25942/2033/2309/694/3066/3065/4087/10891/4303 19 Hepatitis_delta_virus_genotype_I R-HSA-5689603 UCH proteinases 23/362 102/10654 2.9542980966655575e-13 6.701212755851143e-12 4.300608525826369e-12 5715/283899/29844/4798/79913/93973/60/3607/86/8607/221937/54617/3054/125476/8473/51377/83444/8314/55252/171023/54891/10445/7528 23 Hepatitis_delta_virus_genotype_I R-HSA-6782135 Dual incision in TC-NER 19/362 66/10654 3.1173703376935086e-13 6.902748604892769e-12 4.429947321985512e-12 5437/5441/5434/5440/5438/1642/5431/2033/8450/5435/9978/5433/5439/5430/5432/91603/5436/5111/8451 19 Hepatitis_delta_virus_genotype_I R-HSA-6803529 FGFR2 alternative splicing 13/362 26/10654 4.5349958715790826e-13 9.808246885043132e-12 6.294596472913928e-12 3178/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 13 Hepatitis_delta_virus_genotype_I R-HSA-157118 Signaling by NOTCH 34/362 235/10654 5.872645747876089e-13 1.2412637603465371e-11 7.966005117334312e-12 10014/5715/8454/6500/27327/409/1385/8850/27161/3725/1387/4088/8841/192670/4343/2033/408/55294/9978/9611/7027/26523/192669/3066/3065/4851/7157/9759/861/23112/6772/57690/4609/1871 34 Hepatitis_delta_virus_genotype_I R-HSA-8934593 Regulation of RUNX1 Expression and Activity 11/362 17/10654 6.185612964339394e-13 1.2783600126301417e-11 8.20407614217646e-12 27327/27161/192670/4343/865/26523/192669/861/5371/23112/57690 11 Hepatitis_delta_virus_genotype_I R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 13/362 27/10654 8.479970780664603e-13 1.67795166511023e-11 1.076851832617431e-11 5437/5441/5434/5440/5438/5431/5435/5433/6829/5439/5430/5432/5436 13 Hepatitis_delta_virus_genotype_I R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 13/362 27/10654 8.479970780664603e-13 1.67795166511023e-11 1.076851832617431e-11 5437/5441/5434/5440/5438/5431/5435/5433/6829/5439/5430/5432/5436 13 Hepatitis_delta_virus_genotype_I R-HSA-400253 Circadian Clock 19/362 70/10654 1.0098859925851037e-12 1.9566541106336385e-11 1.2557135039380565e-11 8454/6500/1385/1408/1387/10499/23054/1386/6720/23411/8841/5465/2033/9611/8204/8648/6256/10891/10498 19 Hepatitis_delta_virus_genotype_I R-HSA-167161 HIV Transcription Initiation 16/362 47/10654 1.3079135816508727e-12 2.2115629653369303e-11 1.4193052646814254e-11 2958/5437/5441/5434/5440/6908/5438/5431/5435/5433/5439/5430/5432/5436/2957/8148 16 Hepatitis_delta_virus_genotype_I R-HSA-167162 RNA Polymerase II HIV Promoter Escape 16/362 47/10654 1.3079135816508727e-12 2.2115629653369303e-11 1.4193052646814254e-11 2958/5437/5441/5434/5440/6908/5438/5431/5435/5433/5439/5430/5432/5436/2957/8148 16 Hepatitis_delta_virus_genotype_I R-HSA-73776 RNA Polymerase II Promoter Escape 16/362 47/10654 1.3079135816508727e-12 2.2115629653369303e-11 1.4193052646814254e-11 2958/5437/5441/5434/5440/6908/5438/5431/5435/5433/5439/5430/5432/5436/2957/8148 16 Hepatitis_delta_virus_genotype_I R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 16/362 47/10654 1.3079135816508727e-12 2.2115629653369303e-11 1.4193052646814254e-11 2958/5437/5441/5434/5440/6908/5438/5431/5435/5433/5439/5430/5432/5436/2957/8148 16 Hepatitis_delta_virus_genotype_I R-HSA-75953 RNA Polymerase II Transcription Initiation 16/362 47/10654 1.3079135816508727e-12 2.2115629653369303e-11 1.4193052646814254e-11 2958/5437/5441/5434/5440/6908/5438/5431/5435/5433/5439/5430/5432/5436/2957/8148 16 Hepatitis_delta_virus_genotype_I R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 16/362 47/10654 1.3079135816508727e-12 2.2115629653369303e-11 1.4193052646814254e-11 2958/5437/5441/5434/5440/6908/5438/5431/5435/5433/5439/5430/5432/5436/2957/8148 16 Hepatitis_delta_virus_genotype_I R-HSA-9024446 NR1H2 and NR1H3-mediated signaling 16/362 47/10654 1.3079135816508727e-12 2.2115629653369303e-11 1.4193052646814254e-11 27327/27161/6720/8841/192670/4343/2033/9611/26523/8204/192669/8648/6256/23112/7376/57690 16 Hepatitis_delta_virus_genotype_I R-HSA-72086 mRNA Capping 13/362 29/10654 2.697155475883862e-12 4.479204629592842e-11 2.8745999150867473e-11 5437/5441/5434/5440/5438/5431/5435/5433/6829/5439/5430/5432/5436 13 Hepatitis_delta_virus_genotype_I R-HSA-2262752 Cellular responses to stress 49/362 479/10654 2.954273508201858e-12 4.8201304607504e-11 3.093394421330477e-11 2475/5715/27327/5931/2353/1017/5925/7014/7013/5928/367/3725/10524/1387/4683/57634/23411/192670/3309/4343/8726/4790/2033/23512/648/9978/112399/1029/7027/26523/7321/7428/192669/2146/7157/8453/5970/57521/6045/6667/23112/10919/57690/3308/1870/6015/4193/1871/64223 49 Hepatitis_delta_virus_genotype_I R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 14/362 37/10654 6.401106554965927e-12 1.0263843269169504e-10 6.58698260737873e-11 27327/27161/8841/192670/4343/2033/9611/26523/192669/8648/6256/23112/7376/57690 14 Hepatitis_delta_virus_genotype_I R-HSA-8953897 Cellular responses to external stimuli 49/362 493/10654 8.537271726379073e-12 1.3457055433105997e-10 8.636276661653763e-11 2475/5715/27327/5931/2353/1017/5925/7014/7013/5928/367/3725/10524/1387/4683/57634/23411/192670/3309/4343/8726/4790/2033/23512/648/9978/112399/1029/7027/26523/7321/7428/192669/2146/7157/8453/5970/57521/6045/6667/23112/10919/57690/3308/1870/6015/4193/1871/64223 49 Hepatitis_delta_virus_genotype_I R-HSA-3899300 SUMOylation of transcription cofactors 15/362 45/10654 9.502072960861551e-12 1.4728213089335404e-10 9.452062050541226e-11 115426/1387/10499/1616/25942/2033/648/7703/8204/1655/8648/6045/10891/6015/4869 15 Hepatitis_delta_virus_genotype_I R-HSA-8986944 Transcriptional Regulation by MECP2 17/362 62/10654 1.3532315623973642e-11 2.0631235295566373e-10 1.3240419255898283e-10 27327/1385/27161/8841/6657/192670/25942/4343/54487/9611/26523/192669/3066/3065/4204/23112/57690 17 Hepatitis_delta_virus_genotype_I R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 15/362 47/10654 1.9463641868206737e-11 2.880479996391087e-10 1.8485932744241608e-10 10014/8454/6500/8850/1387/8841/2033/55294/9978/9611/3066/3065/4851/9759/4609 15 Hepatitis_delta_virus_genotype_I R-HSA-113418 Formation of the Early Elongation Complex 13/362 33/10654 2.0132387071550607e-11 2.880479996391087e-10 1.8485932744241608e-10 5437/5441/5434/5440/5438/5431/5435/5433/6829/5439/5430/5432/5436 13 Hepatitis_delta_virus_genotype_I R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 13/362 33/10654 2.0132387071550607e-11 2.880479996391087e-10 1.8485932744241608e-10 5437/5441/5434/5440/5438/5431/5435/5433/6829/5439/5430/5432/5436 13 Hepatitis_delta_virus_genotype_I R-HSA-1839126 FGFR2 mutant receptor activation 13/362 33/10654 2.0132387071550607e-11 2.880479996391087e-10 1.8485932744241608e-10 5437/5441/5434/5440/2247/5438/5431/5435/5433/5439/5430/5432/5436 13 Hepatitis_delta_virus_genotype_I R-HSA-170834 Signaling by TGF-beta Receptor Complex 18/362 73/10654 2.3890056004174895e-11 3.3663260733155536e-10 2.1603926243009834e-10 4089/57154/23327/3726/4088/64750/142/9611/7027/7321/51377/3065/2280/9040/10273/4087/6667/4609 18 Hepatitis_delta_virus_genotype_I R-HSA-2559580 Oxidative Stress Induced Senescence 23/362 125/10654 2.6315084983303976e-11 3.652690900667567e-10 2.3441717494946354e-10 27327/5931/2353/5928/3725/192670/4343/8726/23512/648/1029/7027/26523/192669/2146/7157/6045/23112/57690/1870/6015/4193/1871 23 Hepatitis_delta_virus_genotype_I R-HSA-6807505 RNA polymerase II transcribes snRNA genes 18/362 74/10654 3.060206621723607e-11 4.18528258559258e-10 2.685970827426138e-10 2958/5437/5441/5434/5440/6908/5438/5431/5435/5433/6829/5439/5430/5432/5436/5451/6667/2957 18 Hepatitis_delta_virus_genotype_I R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 13/362 34/10654 3.160419116650844e-11 4.1988425406932646e-10 2.694673141565457e-10 5437/5441/5434/5440/5438/5431/5435/5433/6829/5439/5430/5432/5436 13 Hepatitis_delta_virus_genotype_I R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 13/362 34/10654 3.160419116650844e-11 4.1988425406932646e-10 2.694673141565457e-10 5437/5441/5434/5440/5438/5431/5435/5433/6829/5439/5430/5432/5436 13 Hepatitis_delta_virus_genotype_I R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 12/362 29/10654 6.091476979100387e-11 7.868157764671333e-10 5.049513811622689e-10 5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 12 Hepatitis_delta_virus_genotype_I R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 12/362 29/10654 6.091476979100387e-11 7.868157764671333e-10 5.049513811622689e-10 4089/2308/4287/6720/4088/25942/2309/3066/3065/4087/10891/4303 12 Hepatitis_delta_virus_genotype_I R-HSA-167287 HIV elongation arrest and recovery 13/362 36/10654 7.398571204437948e-11 9.298204351523368e-10 5.967268667021786e-10 5437/5441/5434/5440/5438/5431/5435/5433/6829/5439/5430/5432/5436 13 Hepatitis_delta_virus_genotype_I R-HSA-167290 Pausing and recovery of HIV elongation 13/362 36/10654 7.398571204437948e-11 9.298204351523368e-10 5.967268667021786e-10 5437/5441/5434/5440/5438/5431/5435/5433/6829/5439/5430/5432/5436 13 Hepatitis_delta_virus_genotype_I R-HSA-8878166 Transcriptional regulation by RUNX2 22/362 121/10654 9.183876174445881e-11 1.1388006456312893e-9 7.308431987243248e-10 4089/5715/8454/6500/57154/4086/5925/367/7291/6502/8841/581/55294/9978/865/9759/861/10273/4091/6772/2099/10891 22 Hepatitis_delta_virus_genotype_I R-HSA-5633007 Regulation of TP53 Activity 25/362 160/10654 1.4349604653531298e-10 1.7559384641821193e-9 1.1269010856720562e-9 2475/672/5931/1017/1460/5928/10524/4683/1616/6908/10419/2033/1029/1459/3066/3065/7157/1457/9219/6790/5371/10919/8148/4193/64223 25 Hepatitis_delta_virus_genotype_I R-HSA-9006936 Signaling by TGF-beta family members 20/362 102/10654 1.6252375825564007e-10 1.9629492880226658e-9 1.2597535328906074e-9 4089/57154/4086/23327/3726/4088/64750/142/9611/7027/7321/51377/3065/2280/9040/10273/4087/4091/6667/4609 20 Hepatitis_delta_virus_genotype_I R-HSA-212165 Epigenetic regulation of gene expression 24/362 149/10654 1.7709751929648256e-10 2.1115473454580615e-9 1.3551186699204536e-9 5931/8850/5928/29947/5437/5441/5434/5440/6908/23411/60/25942/8932/8726/2033/23512/5435/8819/2146/3066/3065/9219/23309/10919 24 Hepatitis_delta_virus_genotype_I R-HSA-167172 Transcription of the HIV genome 17/362 73/10654 2.297444909734495e-10 2.6707797075663506e-9 1.7140148208150772e-9 2958/5437/5441/5434/5440/6908/5438/5431/5435/5433/6829/5439/5430/5432/5436/2957/8148 17 Hepatitis_delta_virus_genotype_I R-HSA-1980143 Signaling by NOTCH1 17/362 73/10654 2.297444909734495e-10 2.6707797075663506e-9 1.7140148208150772e-9 10014/8454/6500/409/8850/1387/8841/2033/408/55294/9978/9611/3066/3065/4851/9759/4609 17 Hepatitis_delta_virus_genotype_I R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 15/362 56/10654 3.184057625571685e-10 3.65576986639712e-9 2.346147724105452e-9 1385/1387/10499/23054/1386/2551/8841/5465/3054/2553/9611/8648/6256/10891/10498 15 Hepatitis_delta_virus_genotype_I R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 15/362 58/10654 5.478272961783037e-10 5.924178900532819e-9 3.801934846182353e-9 10014/8454/6500/8850/1387/8841/2033/55294/9978/9611/3066/3065/4851/9759/4609 15 Hepatitis_delta_virus_genotype_I R-HSA-2644603 Signaling by NOTCH1 in Cancer 15/362 58/10654 5.478272961783037e-10 5.924178900532819e-9 3.801934846182353e-9 10014/8454/6500/8850/1387/8841/2033/55294/9978/9611/3066/3065/4851/9759/4609 15 Hepatitis_delta_virus_genotype_I R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 15/362 58/10654 5.478272961783037e-10 5.924178900532819e-9 3.801934846182353e-9 10014/8454/6500/8850/1387/8841/2033/55294/9978/9611/3066/3065/4851/9759/4609 15 Hepatitis_delta_virus_genotype_I R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 15/362 58/10654 5.478272961783037e-10 5.924178900532819e-9 3.801934846182353e-9 10014/8454/6500/8850/1387/8841/2033/55294/9978/9611/3066/3065/4851/9759/4609 15 Hepatitis_delta_virus_genotype_I R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 15/362 58/10654 5.478272961783037e-10 5.924178900532819e-9 3.801934846182353e-9 10014/8454/6500/8850/1387/8841/2033/55294/9978/9611/3066/3065/4851/9759/4609 15 Hepatitis_delta_virus_genotype_I R-HSA-5655253 Signaling by FGFR2 in disease 13/362 43/10654 9.435683273090862e-10 1.0086420050545406e-8 6.473118470468866e-9 5437/5441/5434/5440/2247/5438/5431/5435/5433/5439/5430/5432/5436 13 Hepatitis_delta_virus_genotype_I R-HSA-383280 Nuclear Receptor transcription pathway 14/362 52/10654 1.1656182723474882e-9 1.2318465832763227e-8 7.905568904557723e-9 367/5915/5914/7068/5465/2100/7182/3172/9971/9611/8856/6256/7376/2099 14 Hepatitis_delta_virus_genotype_I R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 13/362 44/10654 1.2985732750712918e-9 1.3569361188947206e-8 8.70835064418004e-9 4089/23327/3726/4088/64750/142/9611/7027/7321/3065/4087/6667/4609 13 Hepatitis_delta_virus_genotype_I R-HSA-1226099 Signaling by FGFR in disease 15/362 63/10654 1.9259926934860076e-9 1.9683222032329527e-8 1.2632016856062074e-8 5437/5441/5434/5440/2247/5438/5431/6776/5435/5433/5439/5430/5432/5436/6772 15 Hepatitis_delta_virus_genotype_I R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 15/362 63/10654 1.9259926934860076e-9 1.9683222032329527e-8 1.2632016856062074e-8 1387/5437/5441/5434/5440/4790/5591/2033/5435/1499/2547/1660/5970/4792/7520 15 Hepatitis_delta_virus_genotype_I R-HSA-1368082 RORA activates gene expression 9/362 18/10654 2.028591428165523e-9 2.028591428165523e-8 1.3018804072097922e-8 1387/10499/23054/6720/5465/2033/8648/6256/10498 9 Hepatitis_delta_virus_genotype_I R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 9/362 18/10654 2.028591428165523e-9 2.028591428165523e-8 1.3018804072097922e-8 1647/581/2033/3276/7027/7157/6790/5111/10498 9 Hepatitis_delta_virus_genotype_I R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 17/362 84/10654 2.3593156340159985e-9 2.263487731887568e-8 1.4526287990721573e-8 1387/10499/23054/6720/8841/4790/5465/2033/27332/9611/8202/5970/8648/6256/51003/10891/10498 17 Hepatitis_delta_virus_genotype_I R-HSA-674695 RNA Polymerase II Pre-transcription Events 17/362 84/10654 2.3593156340159985e-9 2.263487731887568e-8 1.4526287990721573e-8 2958/5437/5441/5434/5440/6908/5438/5431/5435/5433/6829/5439/5430/5432/5436/2957/8148 17 Hepatitis_delta_virus_genotype_I R-HSA-167169 HIV Transcription Elongation 13/362 46/10654 2.3932111241065298e-9 2.263487731887568e-8 1.4526287990721573e-8 5437/5441/5434/5440/5438/5431/5435/5433/6829/5439/5430/5432/5436 13 Hepatitis_delta_virus_genotype_I R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 13/362 46/10654 2.3932111241065298e-9 2.263487731887568e-8 1.4526287990721573e-8 5437/5441/5434/5440/5438/5431/5435/5433/6829/5439/5430/5432/5436 13 Hepatitis_delta_virus_genotype_I R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 13/362 46/10654 2.3932111241065298e-9 2.263487731887568e-8 1.4526287990721573e-8 5437/5441/5434/5440/5438/5431/5435/5433/6829/5439/5430/5432/5436 13 Hepatitis_delta_virus_genotype_I R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 12/362 38/10654 2.4095191984609593e-9 2.263487731887568e-8 1.4526287990721573e-8 1460/86/10138/2033/648/865/1459/1457/861/23429/6045/6015 12 Hepatitis_delta_virus_genotype_I R-HSA-8878159 Transcriptional regulation by RUNX3 18/362 96/10654 2.905833937295478e-9 2.7024255616847945e-8 1.734324044680564e-8 4089/5715/57154/8850/1387/4088/64750/2033/2309/1499/1029/865/4851/7157/9759/861/4609/4193 18 Hepatitis_delta_virus_genotype_I R-HSA-73762 RNA Polymerase I Transcription Initiation 13/362 47/10654 3.207790343110477e-9 2.9537079396957855e-8 1.895588457054341e-8 5931/8850/5928/5437/5441/5434/5440/6908/5435/3066/3065/9219/10919 13 Hepatitis_delta_virus_genotype_I R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 13/362 48/10654 4.265662693018243e-9 3.889280690693104e-8 2.4960069627877643e-8 5437/5441/5434/5440/5438/5431/5435/5433/6829/5439/5430/5432/5436 13 Hepatitis_delta_virus_genotype_I R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 7/362 10/10654 5.426265434643453e-9 4.899443547784865e-8 3.144294840513886e-8 2308/8850/1387/23411/2033/2309/4303 7 Hepatitis_delta_virus_genotype_I R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 13/362 49/10654 5.629745500611904e-9 5.0342916495856445e-8 3.230835727577884e-8 1017/1647/581/9337/2033/3276/7027/7157/6790/5111/10498/7832/4869 13 Hepatitis_delta_virus_genotype_I R-HSA-195721 Signaling by WNT 34/362 331/10654 7.331377273966141e-9 6.493505585512868e-8 4.16730918730707e-8 5715/8454/6500/27327/409/57154/9070/1460/27161/10524/1387/8295/6657/192670/8607/64750/4343/8452/2033/1499/9978/8312/26523/1459/192669/3065/1856/1457/8085/23112/57690/4609/1855/5929 34 Hepatitis_delta_virus_genotype_I R-HSA-168325 Viral Messenger RNA Synthesis 12/362 43/10654 1.17063040436086e-8 1.0270625245807544e-7 6.591335047394315e-8 5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 12 Hepatitis_delta_virus_genotype_I R-HSA-1912408 Pre-NOTCH Transcription and Translation 17/362 93/10654 1.2043728897272129e-8 1.0467913901367365e-7 6.717948140436102e-8 27327/8850/27161/3725/1387/192670/4343/2033/7027/26523/192669/4851/7157/861/23112/57690/1871 17 Hepatitis_delta_virus_genotype_I R-HSA-3214847 HATs acetylate histones 21/362 142/10654 1.2176446715487782e-8 1.0485273560558923e-7 6.72908897434851e-8 5931/8850/10524/1387/10499/57634/1386/8295/60/86/8607/11091/2033/3054/10902/54556/6944/8473/10856/8648/10445 21 Hepatitis_delta_virus_genotype_I R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 19/362 119/10654 1.7002468159964216e-8 1.4506693017217175e-7 9.309898065378763e-8 1387/10499/23054/6720/8841/25942/5465/2033/9971/9611/8202/8648/6256/6667/51003/23309/7376/10891/10498 19 Hepatitis_delta_virus_genotype_I R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 9/362 23/10654 2.9314330211605506e-8 2.4783933724357386e-7 1.590547868897638e-7 4089/23327/4088/64750/142/9611/7321/3065/4087 9 Hepatitis_delta_virus_genotype_I R-HSA-4090294 SUMOylation of intracellular receptors 10/362 30/10654 2.967723210071449e-8 2.4864707976274304e-7 1.595731683367009e-7 367/5914/7068/5465/9971/9759/8856/6256/7376/2099 10 Hepatitis_delta_virus_genotype_I R-HSA-211000 Gene Silencing by RNA 20/362 136/10654 3.007229377710706e-8 2.4970743939919255e-7 1.6025367078589945e-7 27327/27161/5437/5441/5434/5440/192670/5438/5431/5435/54487/5433/26523/5439/192669/5430/5432/5436/23112/57690 20 Hepatitis_delta_virus_genotype_I R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 8/362 17/10654 3.0587220686918606e-8 2.5173553308702925e-7 1.615552317604364e-7 4089/2308/1647/4088/2309/694/4087/4303 8 Hepatitis_delta_virus_genotype_I R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 11/362 38/10654 3.161222164443596e-8 2.578891765730302e-7 1.655044291079888e-7 7020/1387/2064/2033/4435/7022/7021/2099/4609/7528/4869 11 Hepatitis_delta_virus_genotype_I R-HSA-162587 HIV Life Cycle 21/362 152/10654 4.145900747586418e-8 3.352771908917712e-7 2.1516940264361546e-7 23327/2958/5437/5441/5434/5440/6908/5438/5431/5435/5433/6829/2547/5439/5430/5432/5478/5436/2957/8148/7520 21 Hepatitis_delta_virus_genotype_I R-HSA-2173789 TGF-beta receptor signaling activates SMADs 10/362 32/10654 5.996271447732943e-8 4.80735555723417e-7 3.0851959263743905e-7 4089/57154/23327/4088/64750/51377/2280/9040/10273/4087 10 Hepatitis_delta_virus_genotype_I R-HSA-112382 Formation of RNA Pol II elongation complex 13/362 61/10654 9.725829787460906e-8 7.665272629100545e-7 4.919309089643473e-7 5437/5441/5434/5440/5438/5431/5435/5433/6829/5439/5430/5432/5436 13 Hepatitis_delta_virus_genotype_I R-HSA-75955 RNA Polymerase II Transcription Elongation 13/362 61/10654 9.725829787460906e-8 7.665272629100545e-7 4.919309089643473e-7 5437/5441/5434/5440/5438/5431/5435/5433/6829/5439/5430/5432/5436 13 Hepatitis_delta_virus_genotype_I R-HSA-5654738 Signaling by FGFR2 14/362 73/10654 1.2732024968492893e-7 9.950238000586883e-7 6.385721501225537e-7 3178/5437/5441/5434/5440/2247/5438/5431/5435/5433/5439/5430/5432/5436 14 Hepatitis_delta_virus_genotype_I R-HSA-1912422 Pre-NOTCH Expression and Processing 17/362 109/10654 1.3866292807195498e-7 1.0746376925576511e-6 6.896656159368286e-7 27327/8850/27161/3725/1387/192670/4343/2033/7027/26523/192669/4851/7157/861/23112/57690/1871 17 Hepatitis_delta_virus_genotype_I R-HSA-3232118 SUMOylation of transcription factors 8/362 20/10654 1.448949434625898e-7 1.1136553505802356e-6 7.147058107289117e-7 7158/7020/6670/7022/7021/1029/7157/4193 8 Hepatitis_delta_virus_genotype_I R-HSA-350054 Notch-HLH transcription pathway 9/362 28/10654 2.1305890771411363e-7 1.6241375751977516e-6 1.0423157952882002e-6 10014/8850/1387/8841/9611/3066/3065/4851/9759 9 Hepatitis_delta_virus_genotype_I R-HSA-162599 Late Phase of HIV Life Cycle 19/362 139/10654 2.196615987916444e-7 1.6608559908636527e-6 1.0658804151892371e-6 23327/2958/5437/5441/5434/5440/6908/5438/5431/5435/5433/6829/5439/5430/5432/5478/5436/2957/8148 19 Hepatitis_delta_virus_genotype_I R-HSA-73856 RNA Polymerase II Transcription Termination 13/362 67/10654 3.1242505939603065e-7 2.34318794547023e-6 1.5037776627975325e-6 10921/6637/9984/6635/6634/26097/9775/10189/4116/55339/6628/6636/8106 13 Hepatitis_delta_virus_genotype_I R-HSA-162906 HIV Infection 25/362 233/10654 3.3901141962823743e-7 2.5222449620340867e-6 1.6186903151933524e-6 5715/6500/23327/2958/5437/5441/5434/5440/6908/5438/5431/5435/9978/5433/6829/2547/5439/5430/5432/5478/5436/2957/8148/7520/4869 25 Hepatitis_delta_virus_genotype_I R-HSA-1989781 PPARA activates gene expression 17/362 117/10654 3.9643283301642616e-7 2.9260518627402885e-6 1.8778397353409658e-6 1387/10499/23054/6720/8841/5465/2033/9971/9611/8202/8648/6256/6667/51003/7376/10891/10498 17 Hepatitis_delta_virus_genotype_I R-HSA-1592230 Mitochondrial biogenesis 15/362 95/10654 6.464722143482496e-7 4.734009128691907e-6 3.038124703982242e-6 1385/1387/10499/23054/1386/2551/8841/5465/3054/2553/9611/8648/6256/10891/10498 15 Hepatitis_delta_virus_genotype_I R-HSA-8939902 Regulation of RUNX2 expression and activity 13/362 73/10654 8.832798416857377e-7 6.417580099747938e-6 4.118582814439254e-6 5715/8454/6500/57154/7291/6502/55294/9978/865/10273/6772/2099/10891 13 Hepatitis_delta_virus_genotype_I R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 8/362 25/10654 1.071468178250005e-6 7.724538029244222e-6 4.957343590924135e-6 2475/1385/2308/6199/2309/4303/4193/64223 8 Hepatitis_delta_virus_genotype_I R-HSA-8866907 Activation of the TFAP2 (AP-2) family of transcription factors 6/362 12/10654 1.147386078852553e-6 8.208223487175956e-6 5.267756329630749e-6 7020/1387/2033/4435/7022/7021 6 Hepatitis_delta_virus_genotype_I R-HSA-190236 Signaling by FGFR 14/362 87/10654 1.20923825121724e-6 8.584668501007888e-6 5.509345829169747e-6 3178/5437/5441/5434/5440/2247/5438/5431/5435/5433/5439/5430/5432/5436 14 Hepatitis_delta_virus_genotype_I R-HSA-5696395 Formation of Incision Complex in GG-NER 10/362 43/10654 1.276051129793986e-6 8.990360232639447e-6 5.7697048691641946e-6 5887/1642/8450/9978/142/1069/5886/1643/7508/8451 10 Hepatitis_delta_virus_genotype_I R-HSA-5687128 MAPK6/MAPK4 signaling 14/362 89/10654 1.6044037473599858e-6 1.1218763045449525e-5 7.199817370424313e-6 5715/27327/2308/27161/3725/192670/4343/2309/26523/192669/8202/23112/57690/4609 14 Hepatitis_delta_virus_genotype_I R-HSA-5250913 Positive epigenetic regulation of rRNA expression 15/362 106/10654 2.703141355988888e-6 1.8621640452367894e-5 1.1950730205424556e-5 5931/8850/5928/5437/5441/5434/5440/6908/60/2033/5435/3066/3065/9219/10919 15 Hepatitis_delta_virus_genotype_I R-HSA-5578749 Transcriptional regulation by small RNAs 15/362 106/10654 2.703141355988888e-6 1.8621640452367894e-5 1.1950730205424556e-5 27327/27161/5437/5441/5434/5440/5438/5431/5435/5433/26523/5439/5430/5432/5436 15 Hepatitis_delta_virus_genotype_I R-HSA-453279 Mitotic G1-G1/S phases 18/362 149/10654 2.8750438864375892e-6 1.9660226576374692e-5 1.2617259161068986e-5 5715/8454/6500/1017/5925/5928/4173/6502/4149/1029/7027/3065/5111/4176/4171/4609/1870/1871 18 Hepatitis_delta_virus_genotype_I R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 15/362 108/10654 3.432257705094611e-6 2.3299267633124004e-5 1.4952670908863958e-5 2353/2308/604/7291/3726/6657/2247/2335/7431/2309/7157/5451/6772/2625/4609 15 Hepatitis_delta_virus_genotype_I R-HSA-6804758 Regulation of TP53 Activity through Acetylation 8/362 30/10654 4.9950659051282985e-6 3.3662400664995055e-5 2.160337428076083e-5 5931/5928/2033/3066/3065/7157/9219/5371 8 Hepatitis_delta_virus_genotype_I R-HSA-8866910 TFAP2 (AP-2) family regulates transcription of growth factors and their receptors 6/362 15/10654 5.697777490139344e-6 3.812182061747906e-5 2.446527706860286e-5 7020/2064/7022/7021/2099/7528 6 Hepatitis_delta_virus_genotype_I R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 8/362 32/10654 8.457527698756786e-6 5.5783693332225614e-5 3.580006125565582e-5 4089/3726/4088/7027/3065/4087/6667/4609 8 Hepatitis_delta_virus_genotype_I R-HSA-8941326 RUNX2 regulates bone development 8/362 32/10654 8.457527698756786e-6 5.5783693332225614e-5 3.580006125565582e-5 4089/4086/5925/367/8841/865/9759/4091 8 Hepatitis_delta_virus_genotype_I R-HSA-9614657 FOXO-mediated transcription of cell death genes 6/362 16/10654 8.856478550030894e-6 5.800369754597698e-5 3.7224783824073506e-5 2308/604/1387/2033/2309/4303 6 Hepatitis_delta_virus_genotype_I R-HSA-2426168 Activation of gene expression by SREBF (SREBP) 9/362 42/10654 9.023912231990748e-6 5.868698164861116e-5 3.76632921276316e-5 1387/10499/23054/6720/5465/8648/6256/6667/10498 9 Hepatitis_delta_virus_genotype_I R-HSA-191859 snRNP Assembly 10/362 53/10654 9.585322905651274e-6 6.14378537149523e-5 3.9428707477507584e-5 6637/6635/6634/6633/10419/1207/6632/79084/6628/6636 10 Hepatitis_delta_virus_genotype_I R-HSA-194441 Metabolism of non-coding RNA 10/362 53/10654 9.585322905651274e-6 6.14378537149523e-5 3.9428707477507584e-5 6637/6635/6634/6633/10419/1207/6632/79084/6628/6636 10 Hepatitis_delta_virus_genotype_I R-HSA-111367 SLBP independent Processing of Histone Pre-mRNAs 5/362 10/10654 9.645082411164556e-6 6.14378537149523e-5 3.9428707477507584e-5 6637/6635/6634/6628/6636 5 Hepatitis_delta_virus_genotype_I R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 35/362 473/10654 1.1624000018490229e-5 7.35395919537137e-5 4.719518804499792e-5 2475/1385/3178/5437/2064/5441/5434/5440/3918/60/2247/4914/5438/581/6455/5431/2335/6776/5435/1499/1399/5433/9611/5439/7057/5430/5432/10273/4734/5436/10252/11140/6772/2099/64223 35 Hepatitis_delta_virus_genotype_I R-HSA-201681 TCF dependent signaling in response to WNT 22/362 233/10654 1.405385099098772e-5 8.83113609568823e-5 5.667520278726911e-5 5715/9070/1460/10524/1387/8295/6657/8607/64750/8452/2033/1499/9978/8312/1459/3065/1856/1457/8085/4609/1855/5929 22 Hepatitis_delta_virus_genotype_I R-HSA-5663205 Infectious disease 30/362 383/10654 1.714485950336302e-5 1.0658115056826053e-4 6.840012718981743e-5 5715/6500/23327/2958/3838/5437/5441/5434/5440/6908/5438/6455/5431/5435/1499/9978/5433/6829/2547/5439/6187/5430/5432/5478/5436/2957/8148/7520/8106/4869 30 Hepatitis_delta_virus_genotype_I R-HSA-77588 SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs 5/362 11/10654 1.7190508156171052e-5 1.0658115056826053e-4 6.840012718981743e-5 6637/6635/6634/6628/6636 5 Hepatitis_delta_virus_genotype_I R-HSA-2173788 Downregulation of TGF-beta receptor signaling 7/362 26/10654 1.8559552107430154e-5 1.1430717523119234e-4 7.335842485125757e-5 57154/23327/4088/64750/51377/10273/4087 7 Hepatitis_delta_virus_genotype_I R-HSA-5689880 Ub-specific processing proteases 21/362 220/10654 1.8694514287618376e-5 1.1438090978608611e-4 7.340574515983114e-5 4089/5715/409/4086/367/6502/8295/4088/8607/64750/408/1540/8312/7157/4792/4087/2625/1643/4303/4609/4193 21 Hepatitis_delta_virus_genotype_I R-HSA-73854 RNA Polymerase I Promoter Clearance 14/362 110/10654 2.0228311058704297e-5 1.2295640055290846e-4 7.890920103395484e-5 5931/8850/5928/5437/5441/5434/5440/6908/8932/5435/3066/3065/9219/10919 14 Hepatitis_delta_virus_genotype_I R-HSA-5683057 MAPK family signaling cascades 25/362 294/10654 2.2570187047962398e-5 1.36300480224708e-4 8.747297372655283e-5 5715/27327/409/2308/27161/3725/2064/60/2247/192670/4343/8452/2335/408/2309/9978/26523/192669/8202/5894/3674/5245/23112/57690/4609 25 Hepatitis_delta_virus_genotype_I R-HSA-1368108 BMAL1:CLOCK,NPAS2 activates circadian gene expression 7/362 27/10654 2.43302195745127e-5 1.450455397711334e-4 9.308525302799392e-5 1387/10499/23054/5465/8648/6256/10498 7 Hepatitis_delta_virus_genotype_I R-HSA-1538133 G0 and Early G1 7/362 27/10654 2.43302195745127e-5 1.450455397711334e-4 9.308525302799392e-5 1017/5928/4149/7027/3065/5111/4609 7 Hepatitis_delta_virus_genotype_I R-HSA-73864 RNA Polymerase I Transcription 14/362 112/10654 2.4876737589370613e-5 1.4735901884149473e-4 9.456996455362478e-5 5931/8850/5928/5437/5441/5434/5440/6908/8932/5435/3066/3065/9219/10919 14 Hepatitis_delta_virus_genotype_I R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 6/362 19/10654 2.751498860640088e-5 1.619553126832457e-4 1.0393736535529179e-4 5928/4149/7027/3065/5111/4609 6 Hepatitis_delta_virus_genotype_I R-HSA-5628897 TP53 Regulates Metabolic Genes 12/362 86/10654 3.126495545938716e-5 1.8196691690378845e-4 1.1678012663774538e-4 2475/27327/27161/192670/4343/26523/192669/7157/57521/23112/57690/64223 12 Hepatitis_delta_virus_genotype_I R-HSA-75067 Processing of Capped Intronless Pre-mRNA 7/362 28/10654 3.150179959302144e-5 1.8196691690378845e-4 1.1678012663774538e-4 6637/6635/6634/55339/6628/6636/8106 7 Hepatitis_delta_virus_genotype_I R-HSA-76071 RNA Polymerase III Transcription Initiation From Type 3 Promoter 7/362 28/10654 3.150179959302144e-5 1.8196691690378845e-4 1.1678012663774538e-4 5437/5441/5434/5440/6908/5435/5451 7 Hepatitis_delta_virus_genotype_I R-HSA-69242 S Phase 17/362 161/10654 3.260419833506647e-5 1.871722497013075e-4 1.2012073070813962e-4 5715/8454/6500/1017/5925/5928/4173/6502/994/4149/9978/7027/7321/5111/4176/4171/4609 17 Hepatitis_delta_virus_genotype_I R-HSA-69206 G1/S Transition 15/362 131/10654 3.680995894040904e-5 2.1002001113239513e-4 1.3478364042112962e-4 5715/8454/6500/1017/5925/5928/4173/6502/4149/7027/3065/5111/4176/4171/4609 15 Hepatitis_delta_virus_genotype_I R-HSA-5621575 CD209 (DC-SIGN) signaling 6/362 21/10654 5.1944142145573154e-5 2.945612938742868e-4 1.8903933630641832e-4 5971/1387/4790/2033/5970/5894 6 Hepatitis_delta_virus_genotype_I R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 13/362 106/10654 5.918644065081612e-5 3.335963018500545e-4 2.1409066570343054e-4 9318/409/8533/6455/10920/408/10987/1856/64708/50813/51138/2873/10980 13 Hepatitis_delta_virus_genotype_I R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 12/362 92/10654 6.177932593873267e-5 3.461130911025385e-4 2.2212351177718087e-4 672/1017/1460/10524/4683/6908/1459/7157/1457/6790/8148/4193 12 Hepatitis_delta_virus_genotype_I R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 5/362 14/10654 6.845299798721911e-5 3.7893623885782004e-4 2.4318828232301526e-4 8841/25942/9611/3065/4204 5 Hepatitis_delta_virus_genotype_I R-HSA-9005895 Pervasive developmental disorders 5/362 14/10654 6.845299798721911e-5 3.7893623885782004e-4 2.4318828232301526e-4 8841/25942/9611/3065/4204 5 Hepatitis_delta_virus_genotype_I R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 12/362 94/10654 7.650216586007464e-5 4.209882499992273e-4 2.701758208823564e-4 8454/6500/1385/2353/3725/1386/351/4790/79155/7321/5970/4792 12 Hepatitis_delta_virus_genotype_I R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF) 9/362 55/10654 8.713479558723038e-5 4.7454376495350333e-4 3.045459136713484e-4 1387/10499/23054/6720/5465/8648/6256/6667/10498 9 Hepatitis_delta_virus_genotype_I R-HSA-5250941 Negative epigenetic regulation of rRNA expression 13/362 110/10654 8.725482129790222e-5 4.7454376495350333e-4 3.045459136713484e-4 5437/5441/5434/5440/6908/23411/25942/8932/5435/8819/3066/3065/23309 13 Hepatitis_delta_virus_genotype_I R-HSA-449147 Signaling by Interleukins 32/362 461/10654 9.583775540774888e-5 5.181925147046887e-4 3.325581843096305e-4 5715/8454/6500/1385/5778/2353/2308/604/3725/7291/3726/1386/351/4088/6657/2247/4790/2335/6776/7431/2309/9978/1399/79155/7157/5970/4792/5478/5451/6772/2625/4609 32 Hepatitis_delta_virus_genotype_I R-HSA-69231 Cyclin D associated events in G1 8/362 44/10654 9.977266732891845e-5 5.332677046890469e-4 3.422329242316804e-4 8454/6500/5925/6502/1029/7027/1870/1871 8 Hepatitis_delta_virus_genotype_I R-HSA-69236 G1 Phase 8/362 44/10654 9.977266732891845e-5 5.332677046890469e-4 3.422329242316804e-4 8454/6500/5925/6502/1029/7027/1870/1871 8 Hepatitis_delta_virus_genotype_I R-HSA-166166 MyD88-independent TLR4 cascade 12/362 99/10654 1.2715894094284503e-4 6.719194038457152e-4 4.31214829632734e-4 8454/6500/1385/2353/3725/1386/351/4790/79155/7321/5970/4792 12 Hepatitis_delta_virus_genotype_I R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 12/362 99/10654 1.2715894094284503e-4 6.719194038457152e-4 4.31214829632734e-4 8454/6500/1385/2353/3725/1386/351/4790/79155/7321/5970/4792 12 Hepatitis_delta_virus_genotype_I R-HSA-3858494 Beta-catenin independent WNT signaling 15/362 146/10654 1.2885939758186437e-4 6.732541559052464e-4 4.320714277286641e-4 5715/27327/409/57154/27161/192670/64750/4343/1499/26523/192669/1856/23112/57690/1855 15 Hepatitis_delta_virus_genotype_I R-HSA-8856828 Clathrin-mediated endocytosis 15/362 146/10654 1.2885939758186437e-4 6.732541559052464e-4 4.320714277286641e-4 9318/409/60/8533/6455/10920/408/10987/1856/64708/10094/50813/51138/2873/10980 15 Hepatitis_delta_virus_genotype_I R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 11/362 85/10654 1.3398641903452035e-4 6.846558774840875e-4 4.3938866161118004e-4 8454/6500/1385/2353/3725/1386/351/4790/79155/5970/4792 11 Hepatitis_delta_virus_genotype_I R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 11/362 85/10654 1.3398641903452035e-4 6.846558774840875e-4 4.3938866161118004e-4 8454/6500/1385/2353/3725/1386/351/4790/79155/5970/4792 11 Hepatitis_delta_virus_genotype_I R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 11/362 85/10654 1.3398641903452035e-4 6.846558774840875e-4 4.3938866161118004e-4 5715/8454/6500/1017/5925/5928/6502/994/4149/7027/4609 11 Hepatitis_delta_virus_genotype_I R-HSA-975871 MyD88 cascade initiated on plasma membrane 11/362 85/10654 1.3398641903452035e-4 6.846558774840875e-4 4.3938866161118004e-4 8454/6500/1385/2353/3725/1386/351/4790/79155/5970/4792 11 Hepatitis_delta_virus_genotype_I R-HSA-2219528 PI3K/AKT Signaling in Cancer 12/362 101/10654 1.5429390755402058e-4 7.841165793728914e-4 5.032191290372716e-4 2475/1385/2308/2064/6199/2247/2100/2309/2099/4303/4193/64223 12 Hepatitis_delta_virus_genotype_I R-HSA-5693532 DNA Double-Strand Break Repair 16/362 166/10654 1.6451842480114521e-4 8.315333427449187e-4 5.336495815918154e-4 672/1017/7158/6047/22976/10524/4683/3838/5591/142/2070/2547/7157/8314/5111/7520 16 Hepatitis_delta_virus_genotype_I R-HSA-6804757 Regulation of TP53 Degradation 7/362 36/10654 1.7569286986548243e-4 8.784643493274122e-4 5.637682920980675e-4 2475/1017/1616/1029/7157/4193/64223 7 Hepatitis_delta_virus_genotype_I R-HSA-76046 RNA Polymerase III Transcription Initiation 7/362 36/10654 1.7569286986548243e-4 8.784643493274122e-4 5.637682920980675e-4 5437/5441/5434/5440/6908/5435/5451 7 Hepatitis_delta_virus_genotype_I R-HSA-9022699 MECP2 regulates neuronal receptors and channels 5/362 17/10654 1.944680213400992e-4 9.671404269855201e-4 6.206775575560723e-4 1385/25942/3066/3065/4204 5 Hepatitis_delta_virus_genotype_I R-HSA-6806003 Regulation of TP53 Expression and Degradation 7/362 37/10654 2.1044539928685013e-4 0.001041033092216865 6.68099335921859e-4 2475/1017/1616/1029/7157/4193/64223 7 Hepatitis_delta_virus_genotype_I R-HSA-9616222 Transcriptional regulation of granulopoiesis 11/362 90/10654 2.245633566006514e-4 0.0011037985291494857 7.083800407784476e-4 1385/1017/5914/2033/865/7027/861/6256/4297/5371/4609 11 Hepatitis_delta_virus_genotype_I R-HSA-4086398 Ca2+ pathway 9/362 62/10654 2.2550722638537882e-4 0.0011037985291494857 7.083800407784476e-4 27327/27161/192670/4343/1499/26523/192669/23112/57690 9 Hepatitis_delta_virus_genotype_I R-HSA-76066 RNA Polymerase III Transcription Initiation From Type 2 Promoter 6/362 27/10654 2.3840994108207444e-4 0.0011608442157399436 7.44990006026653e-4 5437/5441/5434/5440/6908/5435 6 Hepatitis_delta_virus_genotype_I R-HSA-201722 Formation of the beta-catenin:TCF transactivating complex 11/362 91/10654 2.478254253951031e-4 0.0012004044042575306 7.703783782841199e-4 9070/10524/1387/8295/8607/2033/1499/3065/8085/4609/5929 11 Hepatitis_delta_virus_genotype_I R-HSA-168254 Influenza Infection 15/362 155/10654 2.506274092089178e-4 0.0012076864796077386 7.7505176450208e-4 3838/5437/5441/5434/5440/5438/5431/5435/5433/5439/6187/5430/5432/5436/8106 15 Hepatitis_delta_virus_genotype_I R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 10/362 77/10654 2.6140318568447404e-4 0.0012486345190096837 8.013308118602044e-4 672/648/142/1029/7703/1069/6045/5371/7508/6015 10 Hepatitis_delta_virus_genotype_I R-HSA-73780 RNA Polymerase III Chain Elongation 5/362 18/10654 2.618104636633208e-4 0.0012486345190096837 8.013308118602044e-4 5437/5441/5434/5440/5435 5 Hepatitis_delta_virus_genotype_I R-HSA-427413 NoRC negatively regulates rRNA expression 12/362 107/10654 2.673089014025505e-4 0.0012683534607365917 8.139857523912251e-4 5437/5441/5434/5440/6908/25942/8932/5435/8819/3066/3065/23309 12 Hepatitis_delta_virus_genotype_I R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 11/362 92/10654 2.7309094507436336e-4 0.0012892110605033397 8.273714446014642e-4 8454/6500/1385/2353/3725/1386/351/4790/79155/5970/4792 11 Hepatitis_delta_virus_genotype_I R-HSA-201451 Signaling by BMP 6/362 28/10654 2.9483943421545176e-4 0.0013778928332681916 8.842843649836612e-4 4089/57154/4086/64750/7321/4091 6 Hepatitis_delta_virus_genotype_I R-HSA-76061 RNA Polymerase III Transcription Initiation From Type 1 Promoter 6/362 28/10654 2.9483943421545176e-4 0.0013778928332681916 8.842843649836612e-4 5437/5441/5434/5440/6908/5435 6 Hepatitis_delta_virus_genotype_I R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 11/362 93/10654 3.004955990951445e-4 0.001390352771932758 8.922807262998005e-4 8454/6500/1385/2353/3725/1386/351/4790/79155/5970/4792 11 Hepatitis_delta_virus_genotype_I R-HSA-975155 MyD88 dependent cascade initiated on endosome 11/362 93/10654 3.004955990951445e-4 0.001390352771932758 8.922807262998005e-4 8454/6500/1385/2353/3725/1386/351/4790/79155/5970/4792 11 Hepatitis_delta_virus_genotype_I R-HSA-6804760 Regulation of TP53 Activity through Methylation 5/362 19/10654 3.4548741904079095e-4 0.0015906103945937404 0.001020799200605151 10419/2033/7157/10919/4193 5 Hepatitis_delta_virus_genotype_I R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 23/362 309/10654 3.5091969885437535e-4 0.0016076616745545275 0.001031742127303245 5715/8454/6500/57154/25793/23327/6047/6502/64750/8452/55294/9978/84727/7321/7428/8453/9040/10273/4734/10075/80176/8139/9820 23 Hepatitis_delta_virus_genotype_I R-HSA-8934903 Receptor Mediated Mitophagy 4/362 11/10654 3.5786678163761626e-4 0.001631451504524427 0.0010470096242958123 1460/139341/1459/1457 4 Hepatitis_delta_virus_genotype_I R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 11/362 95/10654 3.6229720092614847e-4 0.0016356135769966897 0.0010496806996685038 8454/6500/1385/2353/3725/1386/351/4790/79155/5970/4792 11 Hepatitis_delta_virus_genotype_I R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 11/362 95/10654 3.6229720092614847e-4 0.0016356135769966897 0.0010496806996685038 8454/6500/1385/2353/3725/1386/351/4790/79155/5970/4792 11 Hepatitis_delta_virus_genotype_I R-HSA-69306 DNA Replication 13/362 127/10654 3.723535540589945e-4 0.0016728927791056277 0.001073605213076277 5715/8454/6500/1017/4173/6502/9978/7321/5111/4176/4171/1870/1871 13 Hepatitis_delta_virus_genotype_I R-HSA-5696400 Dual Incision in GG-NER 7/362 41/10654 4.0889229339379895e-4 0.001810808727886824 0.0011621149391192178 1642/8450/9978/142/5111/1643/8451 7 Hepatitis_delta_virus_genotype_I R-HSA-74158 RNA Polymerase III Transcription 7/362 41/10654 4.0889229339379895e-4 0.001810808727886824 0.0011621149391192178 5437/5441/5434/5440/6908/5435/5451 7 Hepatitis_delta_virus_genotype_I R-HSA-749476 RNA Polymerase III Abortive And Retractive Initiation 7/362 41/10654 4.0889229339379895e-4 0.001810808727886824 0.0011621149391192178 5437/5441/5434/5440/6908/5435/5451 7 Hepatitis_delta_virus_genotype_I R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 11/362 97/10654 4.3444614164745045e-4 0.001914857401574071 0.0012288898094991489 8454/6500/1385/2353/3725/1386/351/4790/79155/5970/4792 11 Hepatitis_delta_virus_genotype_I R-HSA-9013694 Signaling by NOTCH4 10/362 82/10654 4.386403112263024e-4 0.0019242240067946282 0.0012349009754980807 5715/8454/6500/8850/1387/4088/2033/55294/9978/4851 10 Hepatitis_delta_virus_genotype_I R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 5/362 20/10654 4.479202866165521e-4 0.0019557082936779036 0.0012551065110530518 8850/1387/4088/2033/4851 5 Hepatitis_delta_virus_genotype_I R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 11/362 98/10654 4.748104064301437e-4 0.0020518978050860473 0.0013168376406154938 8454/6500/1385/2353/3725/1386/351/4790/79155/5970/4792 11 Hepatitis_delta_virus_genotype_I R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 11/362 98/10654 4.748104064301437e-4 0.0020518978050860473 0.0013168376406154938 8454/6500/1385/2353/3725/1386/351/4790/79155/5970/4792 11 Hepatitis_delta_virus_genotype_I R-HSA-186712 Regulation of beta-cell development 7/362 42/10654 4.7656981279417873e-4 0.0020518978050860473 0.0013168376406154938 2308/8850/1387/2033/5080/3172/4851 7 Hepatitis_delta_virus_genotype_I R-HSA-69202 Cyclin E associated events during G1/S transition 10/362 83/10654 4.839736072675478e-4 0.0020741726025752046 0.0013311328417205898 5715/8454/6500/1017/5925/5928/6502/4149/7027/4609 10 Hepatitis_delta_virus_genotype_I R-HSA-168273 Influenza Viral RNA Transcription and Replication 13/362 134/10654 6.25281029882699e-4 0.002667483292618853 0.0017118992947536952 5437/5441/5434/5440/5438/5431/5435/5433/5439/6187/5430/5432/5436 13 Hepatitis_delta_virus_genotype_I R-HSA-73863 RNA Polymerase I Transcription Termination 6/362 32/10654 6.323339229399902e-4 0.0026758501517823814 0.0017172688580199323 5437/5441/5434/5440/6908/5435 6 Hepatitis_delta_virus_genotype_I R-HSA-68949 Orc1 removal from chromatin 9/362 71/10654 6.32996810099058e-4 0.0026758501517823814 0.0017172688580199323 5715/8454/6500/1017/4173/6502/9978/4176/4171 9 Hepatitis_delta_virus_genotype_I R-HSA-72187 mRNA 3'-end processing 8/362 58/10654 7.133666796005092e-4 0.0030019502806718262 0.001926548737001613 10921/9984/26097/9775/10189/4116/55339/8106 8 Hepatitis_delta_virus_genotype_I R-HSA-168898 Toll-like Receptor Cascades 14/362 155/10654 8.019060722674093e-4 0.003359336248687796 0.002155906794573831 8454/6500/1385/81622/2353/3725/1386/351/4790/79155/7321/5970/4792/6279 14 Hepatitis_delta_virus_genotype_I R-HSA-73980 RNA Polymerase III Transcription Termination 5/362 23/10654 8.938807761186173e-4 0.0037278435954722607 0.002392402171627359 5437/5441/5434/5440/5435 5 Hepatitis_delta_virus_genotype_I R-HSA-69052 Switching of origins to a post-replicative state 10/362 90/10654 9.226897621250627e-4 0.0038308101731085193 0.0024584825898726994 5715/8454/6500/1017/4173/6502/9978/7321/4176/4171 10 Hepatitis_delta_virus_genotype_I R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 7/362 47/10654 9.604671310183619e-4 0.003917694876522265 0.0025142422127765983 409/60/2335/408/5894/3674/5245 7 Hepatitis_delta_virus_genotype_I R-HSA-6802949 Signaling by RAS mutants 7/362 47/10654 9.604671310183619e-4 0.003917694876522265 0.0025142422127765983 409/60/2335/408/5894/3674/5245 7 Hepatitis_delta_virus_genotype_I R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 7/362 47/10654 9.604671310183619e-4 0.003917694876522265 0.0025142422127765983 409/60/2335/408/5894/3674/5245 7 Hepatitis_delta_virus_genotype_I R-HSA-9649948 Signaling downstream of RAS mutants 7/362 47/10654 9.604671310183619e-4 0.003917694876522265 0.0025142422127765983 409/60/2335/408/5894/3674/5245 7 Hepatitis_delta_virus_genotype_I R-HSA-8941856 RUNX3 regulates NOTCH signaling 4/362 14/10654 0.0010010166098432657 0.004065263961372215 0.002608946990490148 8850/1387/2033/4851 4 Hepatitis_delta_virus_genotype_I R-HSA-3371571 HSF1-dependent transactivation 5/362 24/10654 0.0010980143391969208 0.004420577209753837 0.002836974847685824 2475/1387/2033/57521/64223 5 Hepatitis_delta_virus_genotype_I R-HSA-933542 TRAF6 mediated NF-kB activation 5/362 24/10654 0.0010980143391969208 0.004420577209753837 0.002836974847685824 351/7706/4790/5970/4792 5 Hepatitis_delta_virus_genotype_I R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 6/362 36/10654 0.001212216345697164 0.004859315523699838 0.0031185420508633935 409/60/2335/408/5894/3674 6 Hepatitis_delta_virus_genotype_I R-HSA-168255 Influenza Life Cycle 13/362 144/10654 0.0012271861056044817 0.0048982106361037244 0.0031435036000801494 5437/5441/5434/5440/5438/5431/5435/5433/5439/6187/5430/5432/5436 13 Hepatitis_E_virus_genotype_1 R-HSA-8856828 Clathrin-mediated endocytosis 119/664 146/10654 4.2379892825160436e-120 4.860973707045902e-117 2.730157306210336e-117 8301/5869/10097/9856/127833/409/163/1080/10092/143425/7311/29978/11037/7037/2017/3949/1173/867/3575/29763/112574/9341/1759/6845/1213/58513/2580/85439/1956/6857/1211/915/161/84251/29924/160/917/23149/950/1129/23048/9146/6572/6455/338/4036/7018/4074/25977/3482/408/6453/26119/7316/274/5868/51429/3312/1175/1950/10618/8218/85021/9829/9322/8673/8674/10093/10109/115548/8027/1856/6869/9892/920/6456/273/5286/29993/9185/55707/551/185/10552/154/10254/26130/3267/6457/8871/10094/8322/5878/2060/1212/554/54874/22905/3092/8976/7314/30011/23208/50618/6233/26052/1601/2885/4952/11252/90019/8867/7474/9026/1785/10096/29988/6844/22848 119 Hepatitis_E_virus_genotype_1 R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 84/664 106/10654 2.926614076513834e-82 1.6784131728806838e-79 9.426777972770877e-80 8301/9856/127833/409/163/1080/143425/7311/29978/11037/7037/3949/1173/867/3575/9341/6845/1213/58513/85439/1956/6857/1211/915/161/84251/29924/160/917/23149/950/1129/9146/6572/6455/338/4036/7018/4074/25977/3482/408/6453/26119/7316/1175/1950/10618/8218/85021/8673/8674/115548/8027/1856/6869/9892/920/6456/9185/55707/551/185/154/10254/3267/6457/8322/2060/1212/554/22905/7314/30011/23208/50618/6233/1601/2885/90019/7474/29988/6844/22848 84 Hepatitis_E_virus_genotype_1 R-HSA-75893 TNF signaling 37/664 43/10654 4.133879465880283e-39 1.580519915788228e-36 8.87696222146924e-37 7124/1147/330/7128/7311/25999/7132/23118/329/81858/9099/841/27005/8517/8772/10616/331/7186/56957/6885/8717/8887/7316/1540/3551/7185/10454/8737/55512/8567/55072/8439/7375/9530/7314/6233/257397 37 Hepatitis_E_virus_genotype_1 R-HSA-917729 Endosomal Sorting Complex Required For Transport (ESCRT) 31/664 32/10654 6.663676441201874e-37 1.9108092195146376e-34 1.0732026268461967e-34 9525/7311/137492/51652/93343/89853/29082/51510/55048/91782/7251/9146/128866/79643/79720/27183/7316/25978/51028/51160/8027/11267/27243/155382/10254/51534/51271/92421/84313/7314/6233 31 Hepatitis_E_virus_genotype_1 R-HSA-73887 Death Receptor Signalling 61/664 141/10654 1.0545269603985467e-36 2.419084847154266e-34 1.358674736345075e-34 7409/7124/355/1147/330/7128/7311/25999/7132/4804/23118/329/9138/81858/26574/9099/843/841/27005/8517/8772/836/4615/10616/331/8874/7186/56957/4790/6885/5599/8717/8887/6453/8837/7316/5584/1540/3551/7185/8743/10454/8737/55512/8567/5970/55072/8795/356/8439/3654/7189/7375/835/9530/8878/6654/7314/6233/8797/257397 61 Hepatitis_E_virus_genotype_1 R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 29/664 30/10654 1.7515298502749513e-34 3.3483412304422817e-32 1.8805899445057372e-32 7124/1147/330/7128/7311/7132/23118/329/81858/9099/27005/8517/10616/331/7186/56957/6885/8717/7316/1540/3551/7185/10454/8737/55072/7375/7314/6233/257397 29 Hepatitis_E_virus_genotype_1 R-HSA-5357905 Regulation of TNFR1 signaling 29/664 33/10654 1.998460530095583e-31 3.2746203257423344e-29 1.8391847284488676e-29 7124/1147/330/7128/7311/25999/7132/329/81858/9099/841/27005/8517/10616/331/7186/56957/8717/8887/7316/1540/3551/7185/8737/8567/55072/7375/7314/6233 29 Hepatitis_E_virus_genotype_1 R-HSA-162588 Budding and maturation of HIV virion 27/664 29/10654 6.224945732514427e-31 8.92501594399256e-29 5.012719458287934e-29 9525/7311/137492/23327/51652/10015/93343/89853/29082/51510/55048/91782/7251/128866/79643/79720/27183/7316/25978/51160/27243/155382/51534/51271/92421/7314/6233 27 Hepatitis_E_virus_genotype_1 R-HSA-168898 Toll-like Receptor Cascades 57/664 155/10654 8.106095625738532e-30 1.0330768536357884e-27 5.802257921581266e-28 2266/1147/2353/1845/330/7311/5598/1432/3725/11035/23118/329/1759/5518/2243/7187/5601/841/8517/8772/2244/4615/5602/338/4790/6885/5599/5600/5606/7316/3551/79155/10454/6416/8737/1848/5970/5336/695/3654/1849/4791/7189/51231/5594/1508/5609/7314/28511/1846/6233/26052/5595/10010/1785/257397/4214 57 Hepatitis_E_virus_genotype_1 R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 45/664 94/10654 1.1461838557984059e-29 1.3146728826007715e-27 7.383837049985521e-28 1147/2353/1845/330/7311/5598/1432/3725/11035/23118/329/5518/7187/5601/841/8517/8772/5602/4790/6885/5599/5600/5606/7316/3551/79155/10454/6416/8737/1848/5970/3654/1849/4791/7189/51231/5594/5609/7314/28511/1846/6233/5595/10010/257397 45 Hepatitis_E_virus_genotype_1 R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 52/664 129/10654 1.4413299661439304e-29 1.5029140646973528e-27 8.441090328039095e-28 1147/2353/1845/330/7311/5598/1432/3725/11035/23118/329/1759/5518/7187/5601/841/8517/8772/4615/5602/4790/6885/5599/5600/5606/7316/3551/79155/10454/6416/8737/1848/5970/5336/695/3654/1849/4791/7189/51231/5594/5609/7314/28511/1846/6233/26052/5595/10010/1785/257397/4214 52 Hepatitis_E_virus_genotype_1 R-HSA-166166 MyD88-independent TLR4 cascade 45/664 99/10654 1.9303407320688514e-28 1.7031544766792097e-26 9.565737069037548e-27 1147/2353/1845/330/7311/5598/1432/3725/11035/23118/329/5518/7187/5601/841/8517/8772/5602/4790/6885/5599/5600/5606/7316/3551/79155/10454/6416/8737/1848/5970/3654/1849/4791/7189/51231/5594/5609/7314/28511/1846/6233/5595/10010/257397 45 Hepatitis_E_virus_genotype_1 R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 45/664 99/10654 1.9303407320688514e-28 1.7031544766792097e-26 9.565737069037548e-27 1147/2353/1845/330/7311/5598/1432/3725/11035/23118/329/5518/7187/5601/841/8517/8772/5602/4790/6885/5599/5600/5606/7316/3551/79155/10454/6416/8737/1848/5970/3654/1849/4791/7189/51231/5594/5609/7314/28511/1846/6233/5595/10010/257397 45 Hepatitis_E_virus_genotype_1 R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 96/664 473/10654 3.269988634120108e-26 2.67905497381126e-24 1.5046864993094034e-24 5295/7409/3082/6093/163/1845/8503/7311/5598/1432/10817/23118/1173/51741/867/3932/3708/10253/5159/1759/5518/2185/23163/1213/5921/5590/58513/4067/3710/1956/1211/161/857/5290/4914/29924/160/26018/8874/9146/9564/3320/6455/5335/2253/4485/2335/2534/5600/5770/7316/3265/5340/1175/1950/5747/5058/4690/6300/3815/5603/8027/998/6774/1848/6456/10653/2066/5062/4233/10254/6457/4734/10252/3709/6692/5125/1849/2060/6772/51231/6714/5594/10193/6654/7314/30011/1846/6233/26052/2885/5595/1398/3249/1785/5774 96 Hepatitis_E_virus_genotype_1 R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 39/664 85/10654 5.554398525895818e-25 3.7475853583544135e-23 2.104824704549994e-23 1147/2353/1845/7311/5598/1432/3725/23118/5518/5601/8517/4615/5602/4790/6885/5599/5600/5606/7316/3551/79155/10454/6416/1848/5970/3654/1849/4791/7189/51231/5594/5609/7314/28511/1846/6233/5595/257397/4214 39 Hepatitis_E_virus_genotype_1 R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 39/664 85/10654 5.554398525895818e-25 3.7475853583544135e-23 2.104824704549994e-23 1147/2353/1845/7311/5598/1432/3725/23118/5518/5601/8517/4615/5602/4790/6885/5599/5600/5606/7316/3551/79155/10454/6416/1848/5970/3654/1849/4791/7189/51231/5594/5609/7314/28511/1846/6233/5595/257397/4214 39 Hepatitis_E_virus_genotype_1 R-HSA-975871 MyD88 cascade initiated on plasma membrane 39/664 85/10654 5.554398525895818e-25 3.7475853583544135e-23 2.104824704549994e-23 1147/2353/1845/7311/5598/1432/3725/23118/5518/5601/8517/4615/5602/4790/6885/5599/5600/5606/7316/3551/79155/10454/6416/1848/5970/3654/1849/4791/7189/51231/5594/5609/7314/28511/1846/6233/5595/257397/4214 39 Hepatitis_E_virus_genotype_1 R-HSA-450294 MAP kinase activation 34/664 64/10654 1.2697957971825034e-24 8.09142099649073e-23 4.544532326758433e-23 1147/2353/1845/7311/5598/1432/3725/23118/5518/5601/8517/5602/4790/6885/5599/5600/5606/7316/3551/79155/10454/6416/1848/3654/1849/7189/51231/5594/5609/7314/1846/6233/5595/257397 34 Hepatitis_E_virus_genotype_1 R-HSA-177929 Signaling by EGFR 30/664 49/10654 2.254057297991087e-24 1.36073880041883e-22 7.642565464656763e-23 5295/7311/867/10253/58513/1956/5290/29924/26018/8874/9146/6455/5335/7316/3265/1950/8027/998/6456/10254/6457/10252/2060/6714/6654/7314/30011/6233/2885/5774 30 Hepatitis_E_virus_genotype_1 R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 40/664 95/10654 7.642557711008556e-24 4.174292235488959e-22 2.344483869241723e-22 1147/2353/1845/7311/5598/1432/3725/23118/5518/5601/8517/4615/5602/4790/6885/5599/5600/5606/7316/3551/79155/10454/6416/1848/5970/695/3654/1849/4791/7189/51231/5594/5609/7314/28511/1846/6233/5595/257397/4214 40 Hepatitis_E_virus_genotype_1 R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 40/664 95/10654 7.642557711008556e-24 4.174292235488959e-22 2.344483869241723e-22 1147/2353/1845/7311/5598/1432/3725/23118/5518/5601/8517/4615/5602/4790/6885/5599/5600/5606/7316/3551/79155/10454/6416/1848/5970/695/3654/1849/4791/7189/51231/5594/5609/7314/28511/1846/6233/5595/257397/4214 40 Hepatitis_E_virus_genotype_1 R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 39/664 92/10654 2.0847477364326282e-23 1.0869116607673748e-21 6.104620166013247e-22 1147/2353/1845/7311/5598/1432/3725/23118/5518/5601/8517/4615/5602/4790/6885/5599/5600/5606/7316/3551/79155/10454/6416/1848/5970/3654/1849/4791/7189/51231/5594/5609/7314/28511/1846/6233/5595/257397/4214 39 Hepatitis_E_virus_genotype_1 R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 40/664 98/10654 3.15374344842253e-23 1.492746903532076e-21 8.383986646736389e-22 1147/2353/1845/7311/5598/1432/3725/23118/5518/5601/8517/4615/5602/4790/6885/5599/5600/5606/7316/3551/79155/10454/6416/1848/5970/695/3654/1849/4791/7189/51231/5594/5609/7314/28511/1846/6233/5595/257397/4214 40 Hepatitis_E_virus_genotype_1 R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 40/664 98/10654 3.15374344842253e-23 1.492746903532076e-21 8.383986646736389e-22 1147/2353/1845/7311/5598/1432/3725/23118/5518/5601/8517/4615/5602/4790/6885/5599/5600/5606/7316/3551/79155/10454/6416/1848/5970/695/3654/1849/4791/7189/51231/5594/5609/7314/28511/1846/6233/5595/257397/4214 40 Hepatitis_E_virus_genotype_1 R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 39/664 93/10654 3.3837331727841306e-23 1.492746903532076e-21 8.383986646736389e-22 1147/2353/1845/7311/5598/1432/3725/23118/5518/5601/8517/4615/5602/4790/6885/5599/5600/5606/7316/3551/79155/10454/6416/1848/5970/3654/1849/4791/7189/51231/5594/5609/7314/28511/1846/6233/5595/257397/4214 39 Hepatitis_E_virus_genotype_1 R-HSA-975155 MyD88 dependent cascade initiated on endosome 39/664 93/10654 3.3837331727841306e-23 1.492746903532076e-21 8.383986646736389e-22 1147/2353/1845/7311/5598/1432/3725/23118/5518/5601/8517/4615/5602/4790/6885/5599/5600/5606/7316/3551/79155/10454/6416/1848/5970/3654/1849/4791/7189/51231/5594/5609/7314/28511/1846/6233/5595/257397/4214 39 Hepatitis_E_virus_genotype_1 R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 37/664 86/10654 1.532310383081886e-22 6.509481516277493e-21 3.656038808756781e-21 5295/10097/7409/10092/7456/147179/25/3708/4067/3710/5290/917/3320/5335/2534/5747/5058/4690/10093/10109/998/5336/3055/6850/10552/695/3709/10094/4771/6714/5594/8976/2885/5595/1398/10096/2268 37 Hepatitis_E_virus_genotype_1 R-HSA-5675482 Regulation of necroptotic cell death 18/664 18/10654 1.618361113400051e-22 6.629500703820923e-21 3.723447373687336e-21 355/330/7311/329/841/8772/331/7186/8717/8837/7316/8743/8737/8795/356/7314/6233/8797 18 Hepatitis_E_virus_genotype_1 R-HSA-5213460 RIPK1-mediated regulated necrosis 19/664 20/10654 1.852624303693263e-22 7.08320025445391e-21 3.978266925825533e-21 355/330/7311/11035/329/841/8772/331/7186/8717/8837/7316/8743/8737/8795/356/7314/6233/8797 19 Hepatitis_E_virus_genotype_1 R-HSA-5218859 Regulated Necrosis 19/664 20/10654 1.852624303693263e-22 7.08320025445391e-21 3.978266925825533e-21 355/330/7311/11035/329/841/8772/331/7186/8717/8837/7316/8743/8737/8795/356/7314/6233/8797 19 Hepatitis_E_virus_genotype_1 R-HSA-448424 Interleukin-17 signaling 34/664 72/10654 1.9317942940526027e-22 7.14763888799463e-21 4.014458770662795e-21 1147/2353/1845/7311/5598/1432/3725/23118/5518/5601/8517/5602/4790/6885/5599/5600/5606/7316/3551/79155/10454/6416/1848/3654/1849/7189/51231/5594/5609/7314/1846/6233/5595/257397 34 Hepatitis_E_virus_genotype_1 R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 39/664 97/10654 2.1799083584136127e-22 7.813609022188793e-21 4.388499721543195e-21 1147/2353/1845/7311/5598/1432/3725/23118/5518/5601/8517/4615/5602/4790/6885/5599/5600/5606/7316/3551/79155/10454/6416/1848/5970/3654/1849/4791/7189/51231/5594/5609/7314/28511/1846/6233/5595/257397/4214 39 Hepatitis_E_virus_genotype_1 R-HSA-449147 Signaling by Interleukins 88/664 461/10654 4.155132570363421e-22 1.444223350971771e-20 8.111454969896058e-21 5295/7409/3082/7124/1147/2353/1845/5743/8503/7311/7132/5598/1432/3725/23118/867/25930/3932/3575/3726/5293/5518/2185/6845/4067/5684/5601/3635/29760/3636/8517/5290/836/4615/3320/5602/4790/2335/6885/5599/2534/5600/5606/5682/7316/4215/3312/3551/79155/10454/5707/6416/998/6774/1848/920/7157/5970/5062/356/3055/6850/1026/3586/3654/1849/7133/4791/7189/3553/6772/51231/5594/829/5609/8878/6654/4609/7314/28511/1846/6233/2885/5595/1398/257397/6844/821 88 Hepatitis_E_virus_genotype_1 R-HSA-182971 EGFR downregulation 23/664 31/10654 6.460163721864049e-22 2.1793552320523718e-20 1.2240310209847673e-20 7311/867/10253/58513/1956/29924/8874/9146/6455/7316/1950/8027/998/6456/10254/6457/10252/2060/7314/30011/6233/2885/5774 23 Hepatitis_E_virus_genotype_1 R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 45/664 134/10654 7.301801691207657e-22 2.3929047256614807e-20 1.3439707172989733e-20 5295/7409/1147/2353/7311/3725/23118/3708/4067/5684/5601/3710/8517/5290/5602/5335/4790/6885/5599/2534/5682/7316/3265/3551/5058/10454/5707/6416/5970/5336/5062/6850/695/3709/8915/7189/5594/5609/6654/7314/6233/2885/5595/257397/4214 45 Hepatitis_E_virus_genotype_1 R-HSA-9615710 Microautophagy 24/664 35/10654 1.7229240091848977e-21 5.489427329264104e-20 3.0831271743308697e-20 1080/7311/137492/51652/93343/89853/29082/55048/91782/7251/128866/79643/79720/7316/3312/11315/25978/51160/27243/155382/51271/92421/7314/6233 24 Hepatitis_E_virus_genotype_1 R-HSA-187037 Signaling by NTRK1 (TRKA) 34/664 80/10654 1.333808102892712e-20 4.134805118967407e-19 2.322305999915618e-19 5295/163/1845/5598/1432/1173/1759/5518/1213/1211/161/5290/4914/160/5335/5600/3265/1175/6300/5603/6774/1848/6456/1849/51231/6714/5594/6654/1846/26052/2885/5595/1398/1785 34 Hepatitis_E_virus_genotype_1 R-HSA-166520 Signaling by NTRKs 37/664 101/10654 1.1728842841996485e-19 3.540258615728939e-18 1.9883800053467728e-18 5295/163/1845/5598/1432/10817/1173/1759/5518/1213/1211/161/5290/4914/160/5335/2534/5600/3265/1175/6300/5603/6774/1848/6456/5125/1849/51231/6714/5594/6654/1846/26052/2885/5595/1398/1785 37 Hepatitis_E_virus_genotype_1 R-HSA-5663205 Infectious disease 75/664 383/10654 1.381161309592743e-19 4.029771584946376e-18 2.2633141008463105e-18 9150/9525/127833/7514/84168/163/928/7311/137492/23327/11168/3303/9883/51652/1173/867/10015/3932/1213/93343/89853/5684/5903/29082/51510/55048/6857/1211/161/999/91782/160/7251/9146/3320/6455/128866/79643/2534/5606/79720/5682/27183/7316/1175/25978/51160/5707/2959/6416/8027/27243/920/6456/5062/4233/3055/155382/10254/8086/51534/6457/51271/2060/92421/6714/5609/7314/30011/6233/2885/6878/79902/6844/821 75 Hepatitis_E_virus_genotype_1 R-HSA-168638 NOD1/2 Signaling Pathway 23/664 36/10654 1.4053257488914999e-19 4.029771584946376e-18 2.2633141008463105e-18 1147/330/7128/7311/1432/23118/329/841/8517/6885/5600/7316/1540/3551/6300/5603/10454/3654/7189/835/7314/6233/257397 23 Hepatitis_E_virus_genotype_1 R-HSA-6807004 Negative regulation of MET activity 18/664 21/10654 1.8018627153428436e-19 5.04082081584937e-18 2.8311681175605147e-18 3082/7311/867/26018/9146/6455/5770/7316/8027/6456/4233/10254/6457/2060/7314/30011/6233/2885 18 Hepatitis_E_virus_genotype_1 R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 15/664 15/10654 7.160303077299107e-19 1.9554446737290655e-17 1.0982720509541488e-17 7311/867/9146/6455/7316/8027/6456/4233/10254/6457/2060/7314/30011/6233/2885 15 Hepatitis_E_virus_genotype_1 R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 27/664 55/10654 1.2467613226063949e-18 3.325663341929151e-17 1.867852948433571e-17 7295/1147/330/7128/7311/1432/23118/329/841/8517/4790/6885/5600/7316/1540/3551/6300/5603/10454/5970/3654/4791/7189/835/7314/6233/257397 27 Hepatitis_E_virus_genotype_1 R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 21/664 32/10654 2.422328421234952e-18 6.314569770810204e-17 3.5465669708033276e-17 5295/7409/930/3708/5293/4067/29760/3710/118788/27071/2534/4690/973/5336/6850/695/3709/974/6654/30011/2885 21 Hepatitis_E_virus_genotype_1 R-HSA-8876384 Listeria monocytogenes entry into host cells 17/664 20/10654 2.5399287539068075e-18 6.473996179402462e-17 3.636108531908693e-17 7311/867/999/9146/6455/7316/8027/6456/4233/10254/6457/2060/6714/7314/30011/6233/2885 17 Hepatitis_E_virus_genotype_1 R-HSA-6806834 Signaling by MET 31/664 79/10654 1.1137363052622697e-17 2.7770772655126593e-16 1.5597405465000207e-16 5295/3082/7311/867/23163/5290/26018/9146/6455/2335/5770/7316/3265/5747/8027/6774/6456/10653/4233/10254/6457/6692/2060/6714/6654/7314/30011/6233/2885/1398/3249 31 Hepatitis_E_virus_genotype_1 R-HSA-983705 Signaling by the B Cell Receptor (BCR) 36/664 112/10654 5.054855590469182e-17 1.2335998643123728e-15 6.928491873162687e-16 5295/7409/930/1147/7311/3708/5293/4067/5684/29760/3710/8517/118788/4790/6885/27071/2534/5682/7316/3265/3551/4690/973/5707/5970/5336/6850/695/3709/8915/974/6654/7314/30011/6233/2885 36 Hepatitis_E_virus_genotype_1 R-HSA-912631 Regulation of signaling by CBL 17/664 22/10654 5.212722172589804e-17 1.2456234024917719e-15 6.996021863212632e-16 5295/7409/8503/7311/867/5293/4067/29760/5290/2534/7316/3055/6850/7314/6233/2885/1398 17 Hepatitis_E_virus_genotype_1 R-HSA-2871796 FCERI mediated MAPK activation 20/664 32/10654 6.60013890565846e-17 1.5449712907735212e-15 8.677303996268481e-16 7409/2353/3725/4067/5601/5602/5335/5599/3265/5058/6416/5336/5062/6850/5594/5609/6654/2885/5595/4214 20 Hepatitis_E_virus_genotype_1 R-HSA-76002 Platelet activation, signaling and aggregation 56/664 262/10654 1.3054272599327431e-16 2.994650134285713e-15 1.681939964376503e-15 5295/5004/2266/7409/409/3082/928/8503/1432/3920/3932/3708/226/2243/5590/197/4067/3710/5290/2244/5005/81/3699/9564/7018/2335/2534/408/5770/213/5340/1950/335/5747/10630/350/998/2770/5336/6850/5894/54495/3709/2147/2771/2773/2/6714/5594/967/6654/2885/5595/1398/139322/3700 56 Hepatitis_E_virus_genotype_1 R-HSA-5357786 TNFR1-induced proapoptotic signaling 13/664 13/10654 1.915848358465177e-16 4.3087805238422706e-15 2.420018979113908e-15 7124/7128/7132/9099/841/27005/8772/7186/56957/8717/1540/8737/7375 13 Hepatitis_E_virus_genotype_1 R-HSA-2682334 EPH-Ephrin signaling 31/664 92/10654 1.7464677599285248e-15 3.852304847380804e-14 2.1636402208021403e-14 10097/6093/163/10092/1173/1759/1213/5921/4067/1211/161/160/8874/2534/6453/3265/1175/5747/8218/5058/10093/10109/998/5062/10552/10094/1969/1212/6714/8976/10096 31 Hepatitis_E_virus_genotype_1 R-HSA-174490 Membrane binding and targetting of GAG proteins 13/664 14/10654 2.5298164523663327e-15 5.373517538637377e-14 3.018026644928257e-14 7311/137492/93343/89853/55048/7251/79720/7316/51160/155382/51271/7314/6233 13 Hepatitis_E_virus_genotype_1 R-HSA-174495 Synthesis And Processing Of GAG, GAGPOL Polyproteins 13/664 14/10654 2.5298164523663327e-15 5.373517538637377e-14 3.018026644928257e-14 7311/137492/93343/89853/55048/7251/79720/7316/51160/155382/51271/7314/6233 13 Hepatitis_E_virus_genotype_1 R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 25/664 61/10654 4.936392709102235e-15 1.0294622613345935e-13 5.781956627694868e-14 10097/7409/10092/7456/147179/25/917/3320/5747/5058/4690/10093/10109/998/6850/10552/695/10094/4771/5594/8976/2885/5595/1398/10096 25 Hepatitis_E_virus_genotype_1 R-HSA-199992 trans-Golgi Network Vesicle Budding 27/664 72/10654 5.568742295248461e-15 1.1405977522589257e-13 6.406147151676801e-14 8301/7037/6845/1213/2580/1211/9146/4074/25977/3482/408/51429/3312/10618/9829/8673/1176/27243/6456/5286/5878/152503/1212/4952/9026/1785/6844 27 Hepatitis_E_virus_genotype_1 R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 16/664 23/10654 7.084430823280326e-15 1.4255863428600937e-13 8.006780542654774e-14 7311/23118/5601/8517/5602/6885/5599/7316/10454/6416/3654/7189/5609/7314/6233/257397 16 Hepatitis_E_virus_genotype_1 R-HSA-162906 HIV Infection 49/664 233/10654 2.2270061627496152e-14 4.404096670127256e-13 2.473553124505925e-13 9150/9525/7514/163/7311/137492/23327/11168/9883/51652/1173/10015/3932/93343/89853/5684/5903/29082/51510/55048/161/91782/160/7251/128866/79643/2534/79720/5682/27183/7316/1175/25978/51160/5707/2959/27243/920/5062/3055/155382/8086/51534/51271/92421/7314/6233/6878/79902 49 Hepatitis_E_virus_genotype_1 R-HSA-3371378 Regulation by c-FLIP 11/664 11/10654 5.096683568763812e-14 9.583436153069003e-13 5.382520007046511e-13 355/841/8772/7186/8717/8837/8743/8737/8795/356/8797 11 Hepatitis_E_virus_genotype_1 R-HSA-5218900 CASP8 activity is inhibited 11/664 11/10654 5.096683568763812e-14 9.583436153069003e-13 5.382520007046511e-13 355/841/8772/7186/8717/8837/8743/8737/8795/356/8797 11 Hepatitis_E_virus_genotype_1 R-HSA-69416 Dimerization of procaspase-8 11/664 11/10654 5.096683568763812e-14 9.583436153069003e-13 5.382520007046511e-13 355/841/8772/7186/8717/8837/8743/8737/8795/356/8797 11 Hepatitis_E_virus_genotype_1 R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 27/664 78/10654 5.5560531561761354e-14 1.027869833892585e-12 5.773012787062472e-13 1147/7128/7311/7187/843/841/7706/8517/8772/5300/7186/4790/2033/8887/7316/1540/3551/8737/5970/4791/7189/57506/7314/28511/6233/10010/4214 27 Hepatitis_E_virus_genotype_1 R-HSA-432722 Golgi Associated Vesicle Biogenesis 23/664 56/10654 5.861353380136748e-14 1.0671384646058493e-12 5.993564358636075e-13 8301/7037/6845/1213/2580/1211/25977/3482/408/51429/3312/10618/9829/8673/1176/6456/5286/5878/152503/4952/9026/1785/6844 23 Hepatitis_E_virus_genotype_1 R-HSA-175474 Assembly Of The HIV Virion 13/664 16/10654 9.002562419964884e-14 1.5886060147230343e-12 8.922377653471271e-13 7311/137492/93343/89853/55048/7251/79720/7316/51160/155382/51271/7314/6233 13 Hepatitis_E_virus_genotype_1 R-HSA-193639 p75NTR signals via NF-kB 13/664 16/10654 9.002562419964884e-14 1.5886060147230343e-12 8.922377653471271e-13 7311/4804/4615/4790/7316/5584/3551/5970/3654/7189/8878/7314/6233 13 Hepatitis_E_virus_genotype_1 R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 14/664 19/10654 1.0163214879901709e-13 1.7398817115294417e-12 9.77201493558499e-13 5295/7311/867/1956/5290/3320/5335/7316/3265/1950/6654/7314/6233/2885 14 Hepatitis_E_virus_genotype_1 R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 14/664 19/10654 1.0163214879901709e-13 1.7398817115294417e-12 9.77201493558499e-13 5295/7311/867/1956/5290/3320/5335/7316/3265/1950/6654/7314/6233/2885 14 Hepatitis_E_virus_genotype_1 R-HSA-177504 Retrograde neurotrophin signalling 12/664 14/10654 2.5329081234487303e-13 4.27242002587602e-12 2.3995971695830082e-12 163/1173/1759/1213/1211/161/4914/160/1175/6456/26052/1785 12 Hepatitis_E_virus_genotype_1 R-HSA-162587 HIV Life Cycle 37/664 152/10654 3.412965827012111e-13 5.673437396496944e-12 3.1864761039380814e-12 9150/9525/7514/7311/137492/23327/11168/9883/51652/10015/93343/89853/5903/29082/51510/55048/91782/7251/128866/79643/79720/27183/7316/25978/51160/2959/27243/920/155382/8086/51534/51271/92421/7314/6233/6878/79902 37 Hepatitis_E_virus_genotype_1 R-HSA-5683057 MAPK family signaling cascades 54/664 294/10654 3.6845455623222366e-13 6.037391085690865e-12 3.390890051340164e-12 2266/409/3082/7514/7311/27161/8826/3725/10817/9462/5159/5518/5921/2243/5684/1956/3337/2244/1843/4343/2253/2335/2534/408/5682/1844/7316/3265/1950/5747/5058/1850/153090/3815/5707/1852/998/1848/2066/5062/4233/5597/5894/896/1849/6714/5594/6654/4609/7314/1846/6233/2885/5595 54 Hepatitis_E_virus_genotype_1 R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 18/664 36/10654 5.058326212664474e-13 8.171690374543875e-12 4.589615481320472e-12 10097/10092/7456/147179/25/5747/4690/10093/10109/998/10552/695/10094/5594/8976/2885/5595/10096 18 Hepatitis_E_virus_genotype_1 R-HSA-162599 Late Phase of HIV Life Cycle 35/664 139/10654 5.160632034404776e-13 8.221173532586496e-12 4.617407609730589e-12 9150/9525/7514/7311/137492/23327/9883/51652/10015/93343/89853/5903/29082/51510/55048/91782/7251/128866/79643/79720/27183/7316/25978/51160/2959/27243/155382/8086/51534/51271/92421/7314/6233/6878/79902 35 Hepatitis_E_virus_genotype_1 R-HSA-5621481 C-type lectin receptors (CLRs) 35/664 142/10654 1.0160006837157015e-12 1.5963736770163144e-11 8.966004591694441e-12 1147/7311/23118/3708/4067/5684/3710/841/8517/4790/6885/2534/2033/5682/7316/3265/3551/5058/10454/5707/9020/5970/5336/5062/6850/5894/3709/8915/4791/7189/3553/6714/7314/6233/257397 35 Hepatitis_E_virus_genotype_1 R-HSA-5099900 WNT5A-dependent internalization of FZD4 12/664 15/10654 1.1948700706059103e-12 1.8438402930560002e-11 1.0355896474558551e-11 409/163/1173/1213/1211/161/160/1175/1856/8322/1212/7474 12 Hepatitis_E_virus_genotype_1 R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 17/664 33/10654 1.2056497121115957e-12 1.8438402930560002e-11 1.0355896474558551e-11 1147/7311/23118/8517/4790/6885/7316/3551/10454/5970/3654/4791/7189/7314/28511/6233/257397 17 Hepatitis_E_virus_genotype_1 R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 20/664 48/10654 1.8930486834927748e-12 2.857008999955543e-11 1.6046340641240698e-11 5295/7409/8503/7311/867/5293/4067/3635/29760/3636/5290/2534/7316/3055/6850/6654/7314/6233/2885/1398 20 Hepatitis_E_virus_genotype_1 R-HSA-209543 p75NTR recruits signalling complexes 11/664 13/10654 3.5408876099484884e-12 5.206920626424251e-11 2.924457783115351e-11 7311/4804/4615/7316/5584/3551/3654/7189/8878/7314/6233 11 Hepatitis_E_virus_genotype_1 R-HSA-209560 NF-kB is activated and signals survival 11/664 13/10654 3.5408876099484884e-12 5.206920626424251e-11 2.924457783115351e-11 7311/4804/4790/7316/3551/5970/3654/7189/8878/7314/6233 11 Hepatitis_E_virus_genotype_1 R-HSA-5654741 Signaling by FGFR3 18/664 40/10654 4.988027722838279e-12 7.242111136829754e-11 4.067518942541008e-11 5295/7311/10817/867/10253/5518/5290/5335/2253/7316/3265/6714/5594/6654/7314/6233/2885/5595 18 Hepatitis_E_virus_genotype_1 R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 16/664 31/10654 5.4190907056145224e-12 7.769621299174822e-11 4.363794094521169e-11 2353/1845/5598/1432/3725/5518/5601/5602/5599/5600/1848/1849/51231/5594/1846/5595 16 Hepatitis_E_virus_genotype_1 R-HSA-5654743 Signaling by FGFR4 18/664 41/10654 8.381100920460666e-12 1.186805278489924e-10 6.66567090750088e-11 5295/7311/10817/867/10253/5518/5290/5335/2253/7316/3265/6714/5594/6654/7314/6233/2885/5595 18 Hepatitis_E_virus_genotype_1 R-HSA-5607764 CLEC7A (Dectin-1) signaling 28/664 101/10654 9.269125819241373e-12 1.2965472334963237e-10 7.282034661586291e-11 1147/7311/23118/3708/5684/3710/841/8517/4790/6885/5682/7316/3551/10454/5707/9020/5970/5336/6850/3709/8915/4791/7189/3553/6714/7314/6233/257397 28 Hepatitis_E_virus_genotype_1 R-HSA-5663202 Diseases of signal transduction 60/664 377/10654 1.0525296273130571e-11 1.454519858467562e-10 8.169285122582004e-11 5295/2266/7409/409/930/3082/7048/1147/8503/7311/8826/867/3932/5293/5159/5518/2243/5684/7046/1956/5290/118788/2244/3320/9444/5335/2253/2335/2534/2033/408/2100/5682/7316/3265/1950/10142/3815/5707/6774/2066/4233/1026/5894/1452/8322/6772/6714/5594/9530/6654/4609/7314/6233/2885/7415/613/4193/5595/9372 60 Hepatitis_E_virus_genotype_1 R-HSA-450302 activated TAK1 mediates p38 MAPK activation 14/664 24/10654 1.2786493294437017e-11 1.7459652153237212e-10 9.806182827312601e-11 7311/1432/23118/8517/6885/5600/5606/7316/10454/3654/7189/7314/6233/257397 14 Hepatitis_E_virus_genotype_1 R-HSA-3928662 EPHB-mediated forward signaling 18/664 42/10654 1.382477527812277e-11 1.8655314404713903e-10 1.04777244213141e-10 10097/6093/10092/5921/4067/2534/6453/3265/5747/5058/10093/10109/998/10552/10094/6714/8976/10096 18 Hepatitis_E_virus_genotype_1 R-HSA-5357801 Programmed Cell Death 38/664 181/10654 2.1193514290552172e-11 2.826623359449226e-10 1.587568022743933e-10 6093/355/1613/330/7311/11035/329/5684/841/999/8772/836/331/7186/5599/8717/5682/8837/7316/4137/5747/1029/9414/637/8743/5707/8737/6774/7157/8795/5062/356/8626/5594/7314/6233/5595/8797 38 Hepatitis_E_virus_genotype_1 R-HSA-8848021 Signaling by PTK6 20/664 54/10654 2.5471058921691694e-11 3.319920975361406e-10 1.864627758382215e-10 120892/7311/867/116985/5921/1956/1796/6421/2908/10657/9564/5770/7316/3265/1950/6774/2066/7314/6233/1398 20 Hepatitis_E_virus_genotype_1 R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 20/664 54/10654 2.5471058921691694e-11 3.319920975361406e-10 1.864627758382215e-10 120892/7311/867/116985/5921/1956/1796/6421/2908/10657/9564/5770/7316/3265/1950/6774/2066/7314/6233/1398 20 Hepatitis_E_virus_genotype_1 R-HSA-1643713 Signaling by EGFR in Cancer 14/664 25/10654 2.7406433910288403e-11 3.532042662370876e-10 1.983765529638853e-10 5295/7311/867/1956/5290/3320/5335/7316/3265/1950/6654/7314/6233/2885 14 Hepatitis_E_virus_genotype_1 R-HSA-4420097 VEGFA-VEGFR2 Pathway 27/664 99/10654 3.321832065077818e-11 4.233490420715841e-10 2.3777324255293854e-10 5295/7409/6093/1432/3708/2185/5921/5590/3710/857/5290/9564/3320/5335/2534/5600/3265/5747/5058/4690/6300/5603/998/5062/3709/6714/1398 27 Hepatitis_E_virus_genotype_1 R-HSA-202403 TCR signaling 29/664 119/10654 1.2372322257076372e-10 1.5594564427325932e-9 8.758659596681018e-10 5295/1147/7311/23118/3932/5684/3635/5788/915/8517/5290/917/5335/4790/6885/5682/7408/7316/3551/5058/4690/5707/920/5970/5062/8915/7189/7314/6233 29 Hepatitis_E_virus_genotype_1 R-HSA-450341 Activation of the AP-1 family of transcription factors 9/664 10/10654 1.2734361045451292e-10 1.5705711956056595e-9 8.821085410091898e-10 2353/1432/3725/5601/5602/5599/5600/5594/5595 9 Hepatitis_E_virus_genotype_1 R-HSA-937042 IRAK2 mediated activation of TAK1 complex 9/664 10/10654 1.2734361045451292e-10 1.5705711956056595e-9 8.821085410091898e-10 7311/23118/6885/7316/10454/7189/7314/6233/257397 9 Hepatitis_E_virus_genotype_1 R-HSA-1295596 Spry regulation of FGF signaling 11/664 16/10654 1.6670936629099495e-10 2.034208969529481e-9 1.1425098787244001e-9 7311/867/10253/5518/7316/6714/5594/7314/6233/2885/5595 11 Hepatitis_E_virus_genotype_1 R-HSA-5140745 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 10/664 13/10654 1.99675695334873e-10 2.4108212899905196e-9 1.354033524043682e-9 163/1173/1213/1211/161/160/1175/1212/4920/7474 10 Hepatitis_E_virus_genotype_1 R-HSA-9607240 FLT3 Signaling 46/664 267/10654 2.0988534474607836e-10 2.5076926085807486e-9 1.4084411292171052e-9 5295/2266/409/3082/7311/8826/10817/9462/5159/5518/5921/2243/5684/1956/5290/2244/1843/2253/2335/2534/408/5682/1844/7316/3265/1950/5747/1850/153090/3815/5707/1852/1848/2066/4233/3055/5894/1849/6714/5594/6654/7314/1846/6233/2885/5595 46 Hepatitis_E_virus_genotype_1 R-HSA-109581 Apoptosis 36/664 178/10654 2.1979543668454824e-10 2.5990243904863593e-9 1.4597374633851713e-9 6093/355/1613/7311/329/5684/841/999/8772/836/331/7186/5599/8717/5682/8837/7316/4137/5747/1029/9414/637/8743/5707/8737/6774/7157/8795/5062/356/8626/5594/7314/6233/5595/8797 36 Hepatitis_E_virus_genotype_1 R-HSA-194138 Signaling by VEGF 27/664 107/10654 2.3200379121397932e-10 2.715391311453411e-9 1.5250947392368998e-9 5295/7409/6093/1432/3708/2185/5921/5590/3710/857/5290/9564/3320/5335/2534/5600/3265/5747/5058/4690/6300/5603/998/5062/3709/6714/1398 27 Hepatitis_E_virus_genotype_1 R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 12/664 20/10654 2.473669600184043e-10 2.8659586175869673e-9 1.609660601076698e-9 1147/330/7311/11035/329/8517/7316/3551/8737/7189/7314/6233 12 Hepatitis_E_virus_genotype_1 R-HSA-5689896 Ovarian tumor domain proteases 16/664 38/10654 2.6553591511505715e-10 3.0456969463697055e-9 1.710610316320158e-9 7128/7311/7187/10318/7706/8517/56957/7316/79155/8737/7157/7189/57506/7314/6233/7415 16 Hepatitis_E_virus_genotype_1 R-HSA-186763 Downstream signal transduction 14/664 29/10654 3.772857059384131e-10 4.284620838726335e-9 2.4064497345941515e-9 5295/5159/5921/5290/9564/5335/3265/4690/6774/6772/6714/6654/2885/1398 14 Hepatitis_E_virus_genotype_1 R-HSA-5654736 Signaling by FGFR1 18/664 50/10654 4.3978856574497986e-10 4.945465538328352e-9 2.7776119941788204e-9 5295/7311/10817/867/10253/5518/5290/5335/2253/7316/3265/6714/5594/6654/7314/6233/2885/5595 18 Hepatitis_E_virus_genotype_1 R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 11/664 17/10654 4.4582249725316525e-10 4.964644702421171e-9 2.7883839378532157e-9 355/841/8772/7186/8717/8837/8743/8737/8795/356/8797 11 Hepatitis_E_virus_genotype_1 R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 26/664 103/10654 4.969253659871273e-10 5.428318045592715e-9 3.048805252973654e-9 5295/7409/930/3082/8503/3932/5293/5159/5518/1956/5290/118788/4615/2253/2534/2100/1950/3815/2066/4233/3654/7189/6714/5594/2885/5595 26 Hepatitis_E_virus_genotype_1 R-HSA-9020702 Interleukin-1 signaling 26/664 103/10654 4.969253659871273e-10 5.428318045592715e-9 3.048805252973654e-9 1147/7311/23118/5684/8517/4615/4790/6885/5682/7316/4215/3551/79155/10454/5707/6416/5970/3654/4791/7189/3553/8878/7314/28511/6233/257397 26 Hepatitis_E_virus_genotype_1 R-HSA-9612973 Autophagy 28/664 119/10654 6.205859314180317e-10 6.715208144683795e-9 3.77158480663193e-9 1080/7311/137492/51652/3920/93343/89853/29082/55048/91782/7251/3320/128866/79643/79720/7316/3312/11315/25978/51160/27243/155382/51271/92421/6714/8878/7314/6233 28 Hepatitis_E_virus_genotype_1 R-HSA-196025 Formation of annular gap junctions 9/664 11/10654 6.616232665531193e-10 6.956048625464901e-9 3.906852437741036e-9 2697/1173/1759/1213/1211/8218/1212/1601/1785 9 Hepatitis_E_virus_genotype_1 R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 9/664 11/10654 6.616232665531193e-10 6.956048625464901e-9 3.906852437741036e-9 7311/23118/6885/7316/10454/7189/7314/6233/257397 9 Hepatitis_E_virus_genotype_1 R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 9/664 11/10654 6.616232665531193e-10 6.956048625464901e-9 3.906852437741036e-9 7311/23118/6885/7316/10454/7189/7314/6233/257397 9 Hepatitis_E_virus_genotype_1 R-HSA-5675221 Negative regulation of MAPK pathway 16/664 40/10654 6.671014374900951e-10 6.956048625464901e-9 3.906852437741036e-9 7311/5518/1843/1844/7316/3265/1850/1852/1848/5894/1849/5594/7314/1846/6233/5595 16 Hepatitis_E_virus_genotype_1 R-HSA-5673001 RAF/MAP kinase cascade 43/664 249/10654 7.708646588759253e-10 7.965601475051229e-9 4.473866014528841e-9 2266/409/3082/7311/8826/10817/9462/5159/5518/5921/2243/5684/1956/2244/1843/2253/2335/2534/408/5682/1844/7316/3265/1950/5747/1850/153090/3815/5707/1852/1848/2066/4233/5894/1849/6714/5594/6654/7314/1846/6233/2885/5595 43 Hepatitis_E_virus_genotype_1 R-HSA-2559583 Cellular Senescence 37/664 195/10654 8.230700132934856e-10 8.42911879685382e-9 4.73419970052268e-9 1032/7295/2353/5925/7311/5598/1432/3725/5601/4343/5602/8881/4790/5599/5600/5606/9448/7316/1029/4217/6416/6774/7157/5970/1026/29945/8697/5594/5609/7314/996/6233/4193/5595/51434/51433/23043 37 Hepatitis_E_virus_genotype_1 R-HSA-1257604 PIP3 activates AKT signaling 44/664 264/10654 1.5527582301418374e-9 1.576118309710343e-8 8.852240678591566e-9 5295/7409/930/3082/57504/1147/8503/7311/1958/27161/3725/3932/5293/5159/5518/5684/1956/5290/118788/4615/331/4343/2253/2534/2100/5682/7316/1950/3815/5707/7157/2066/4233/1026/4734/3654/7189/6714/5594/7314/6233/2885/4193/5595 44 Hepatitis_E_virus_genotype_1 R-HSA-5684996 MAPK1/MAPK3 signaling 43/664 255/10654 1.6535027532492916e-9 1.663655840330647e-8 9.343893674871345e-9 2266/409/3082/7311/8826/10817/9462/5159/5518/5921/2243/5684/1956/2244/1843/2253/2335/2534/408/5682/1844/7316/3265/1950/5747/1850/153090/3815/5707/1852/1848/2066/4233/5894/1849/6714/5594/6654/7314/1846/6233/2885/5595 43 Hepatitis_E_virus_genotype_1 R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 13/664 27/10654 1.6966907515844534e-9 1.692264601797711e-8 9.504574278898725e-9 355/1613/841/8772/836/7186/8717/8837/8743/8737/8795/356/8797 13 Hepatitis_E_virus_genotype_1 R-HSA-5637810 Constitutive Signaling by EGFRvIII 10/664 15/10654 1.869235448387065e-9 1.8324897942734734e-8 1.0292146598406514e-8 5295/867/1956/5290/3320/5335/3265/1950/6654/2885 10 Hepatitis_E_virus_genotype_1 R-HSA-5637812 Signaling by EGFRvIII in Cancer 10/664 15/10654 1.869235448387065e-9 1.8324897942734734e-8 1.0292146598406514e-8 5295/867/1956/5290/3320/5335/3265/1950/6654/2885 10 Hepatitis_E_virus_genotype_1 R-HSA-9006925 Intracellular signaling by second messengers 48/664 305/10654 1.9902930194848033e-9 1.9346322824992114e-8 1.0865828081397857e-8 5295/7409/930/3082/57504/1147/8503/7311/1958/27161/3725/3932/3708/5293/5159/5518/5684/3710/1956/5290/118788/4615/331/4343/5335/2253/2534/2100/5682/7316/1950/3815/5707/7157/2066/4233/1026/4734/3709/3654/7189/6714/5594/7314/6233/2885/4193/5595 48 Hepatitis_E_virus_genotype_1 R-HSA-199418 Negative regulation of the PI3K/AKT network 26/664 110/10654 2.302105808353167e-9 2.2189204724210778e-8 1.2462527684317898e-8 5295/7409/930/3082/8503/3932/5293/5159/5518/1956/5290/118788/4615/2253/2534/2100/1950/3815/2066/4233/3654/7189/6714/5594/2885/5595 26 Hepatitis_E_virus_genotype_1 R-HSA-190873 Gap junction degradation 9/664 12/10654 2.5000847672653734e-9 2.3699150645069284e-8 1.3310586146728218e-8 2697/1173/1759/1213/1211/8218/1212/1601/1785 9 Hepatitis_E_virus_genotype_1 R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 9/664 12/10654 2.5000847672653734e-9 2.3699150645069284e-8 1.3310586146728218e-8 1147/843/841/7706/8517/8772/3551/8737/57506 9 Hepatitis_E_virus_genotype_1 R-HSA-194315 Signaling by Rho GTPases 62/664 455/10654 3.2014248472836077e-9 3.0098641801920474e-8 1.6904849064172288e-8 10097/7409/9055/7514/6093/1080/10092/7456/367/147179/1432/2017/8826/25/55920/9138/116985/5518/5590/5903/5347/999/5300/8874/64837/9912/85360/5600/6453/57522/23002/5747/5058/4690/9322/10093/10109/1856/998/5586/64411/5062/201176/10552/695/10094/4771/2/9212/6714/5594/6654/8976/2885/4952/613/5595/29127/3798/55114/10096/79902 62 Hepatitis_E_virus_genotype_1 R-HSA-1227986 Signaling by ERBB2 17/664 50/10654 3.732401867766959e-9 3.480540603519271e-8 1.954839489151373e-8 5295/7311/1956/5290/3320/5335/2534/7316/3265/1950/2066/6714/10193/6654/7314/6233/2885 17 Hepatitis_E_virus_genotype_1 R-HSA-933542 TRAF6 mediated NF-kB activation 12/664 24/10654 4.2097268247983966e-9 3.893997312938517e-8 2.1870567205234457e-8 1147/7706/8517/7186/4790/3551/5970/4791/7189/57506/28511/4214 12 Hepatitis_E_virus_genotype_1 R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 10/664 16/10654 4.706778918547233e-9 4.318940335658941e-8 2.4257252194955007e-8 1147/7311/8517/4790/7316/3551/79155/6416/7314/6233 10 Hepatitis_E_virus_genotype_1 R-HSA-446652 Interleukin-1 family signaling 29/664 140/10654 7.210683288389449e-9 6.564010898240236e-8 3.686665139928441e-8 1147/7311/23118/25930/5684/8517/4615/4790/6885/5599/5682/7316/4215/3551/79155/10454/5707/6416/6774/5970/3654/4791/7189/3553/8878/7314/28511/6233/257397 29 Hepatitis_E_virus_genotype_1 R-HSA-937041 IKK complex recruitment mediated by RIP1 12/664 25/10654 7.639359012967896e-9 6.87842026596718e-8 3.863252606591029e-8 1147/330/7311/11035/329/8517/7316/3551/8737/7189/7314/6233 12 Hepatitis_E_virus_genotype_1 R-HSA-202670 ERKs are inactivated 9/664 13/10654 7.676005179108972e-9 6.87842026596718e-8 3.863252606591029e-8 1845/5598/5518/1848/1849/51231/5594/1846/5595 9 Hepatitis_E_virus_genotype_1 R-HSA-432720 Lysosome Vesicle Biogenesis 14/664 35/10654 7.944920984734943e-9 7.064204937589907e-8 3.9675982396228366e-8 6845/1213/1211/9146/4074/408/3312/9829/8673/27243/6456/1212/1785/6844 14 Hepatitis_E_virus_genotype_1 R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 10/664 17/10654 1.0793859520395836e-8 9.523505284533865e-8 5.348859940471459e-8 1147/11035/8517/4615/4790/3551/8737/5970/4791/28511 10 Hepatitis_E_virus_genotype_1 R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 20/664 75/10654 1.8352633943085115e-8 1.6069061933372996e-7 9.025160283783118e-8 5295/7409/930/3082/8503/3932/5293/5159/1956/5290/118788/2253/2534/2100/1950/3815/2066/4233/6714/2885 20 Hepatitis_E_virus_genotype_1 R-HSA-198753 ERK/MAPK targets 11/664 22/10654 1.9041240616926695e-8 1.6545684081526455e-7 9.292854272375707e-8 1845/5598/1432/5518/5600/1848/1849/51231/5594/1846/5595 11 Hepatitis_E_virus_genotype_1 R-HSA-1433557 Signaling by SCF-KIT 15/664 43/10654 2.093918625666555e-8 1.8058080177740892e-7 1.0142288871451775e-7 5295/7409/8503/867/3932/4067/5290/2534/3265/3815/6774/6772/6714/6654/2885 15 Hepatitis_E_virus_genotype_1 R-HSA-202424 Downstream TCR signaling 23/664 98/10654 2.243297584899444e-8 1.917943619593968e-7 1.0772096500633311e-7 5295/1147/7311/23118/3932/5684/3635/915/8517/5290/917/4790/6885/5682/7316/3551/5707/920/5970/8915/7189/7314/6233 23 Hepatitis_E_virus_genotype_1 R-HSA-354192 Integrin alphaIIb beta3 signaling 12/664 27/10654 2.2741092612448097e-8 1.917943619593968e-7 1.0772096500633311e-7 2266/2243/2244/9564/2335/5770/5747/6850/6714/6654/2885/1398 12 Hepatitis_E_virus_genotype_1 R-HSA-9006921 Integrin signaling 12/664 27/10654 2.2741092612448097e-8 1.917943619593968e-7 1.0772096500633311e-7 2266/2243/2244/9564/2335/5770/5747/6850/6714/6654/2885/1398 12 Hepatitis_E_virus_genotype_1 R-HSA-69231 Cyclin D associated events in G1 15/664 44/10654 2.996170784682631e-8 2.4902955724862157e-7 1.3986701145886883e-7 1032/5925/7311/25/5518/4067/6502/7316/1029/1163/1026/896/6714/7314/6233 15 Hepatitis_E_virus_genotype_1 R-HSA-69236 G1 Phase 15/664 44/10654 2.996170784682631e-8 2.4902955724862157e-7 1.3986701145886883e-7 1032/5925/7311/25/5518/4067/6502/7316/1029/1163/1026/896/6714/7314/6233 15 Hepatitis_E_virus_genotype_1 R-HSA-389356 CD28 co-stimulation 13/664 33/10654 3.4183023904480866e-8 2.8207142747078814e-7 1.5842491957245204e-7 5295/7409/8503/3932/4067/5290/2534/5058/9020/998/5062/6714/2885 13 Hepatitis_E_virus_genotype_1 R-HSA-2219528 PI3K/AKT Signaling in Cancer 23/664 101/10654 4.112817639287521e-8 3.3695727373305617e-7 1.8925145828901976e-7 5295/7409/930/3082/1147/8503/3932/5293/5159/1956/5290/118788/2253/2534/2100/1950/3815/2066/4233/1026/6714/2885/4193 23 Hepatitis_E_virus_genotype_1 R-HSA-8964038 LDL clearance 10/664 19/10654 4.572019301579303e-8 3.7192242119939437e-7 2.0888957167350008e-7 163/3949/1173/1213/1211/161/160/338/26119/1175 10 Hepatitis_E_virus_genotype_1 R-HSA-937039 IRAK1 recruits IKK complex 9/664 15/10654 4.7958739233171156e-8 3.8467604126186935e-7 2.1605261988002023e-7 1147/7311/8517/7316/3551/3654/7189/7314/6233 9 Hepatitis_E_virus_genotype_1 R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 9/664 15/10654 4.7958739233171156e-8 3.8467604126186935e-7 2.1605261988002023e-7 1147/7311/8517/7316/3551/3654/7189/7314/6233 9 Hepatitis_E_virus_genotype_1 R-HSA-5654732 Negative regulation of FGFR3 signaling 12/664 29/10654 6.045990156465126e-8 4.78732001415813e-7 2.6887898395491903e-7 7311/867/10253/5518/2253/7316/6714/5594/7314/6233/2885/5595 12 Hepatitis_E_virus_genotype_1 R-HSA-5688426 Deubiquitination 44/664 297/10654 6.051973862710801e-8 4.78732001415813e-7 2.6887898395491903e-7 409/7048/1080/330/7128/7311/367/329/7187/5684/7046/6502/9099/27005/10318/7706/8517/9146/7186/56957/6885/2033/408/51651/5682/7316/1540/79155/25862/10454/5707/8027/8737/7157/154/10254/7189/7375/57506/4609/7314/6233/7415/4193 44 Hepatitis_E_virus_genotype_1 R-HSA-437239 Recycling pathway of L1 15/664 47/10654 8.216558137680751e-8 6.45506313967111e-7 3.625474823547672e-7 163/1173/1759/1213/1211/161/160/1808/8986/1175/6456/6714/5594/26052/1785 15 Hepatitis_E_virus_genotype_1 R-HSA-8866427 VLDLR internalisation and degradation 8/664 12/10654 8.646676925330188e-8 6.74676083901614e-7 3.78930632173439e-7 163/1173/1213/1211/161/160/1175/7436 8 Hepatitis_E_virus_genotype_1 R-HSA-193704 p75 NTR receptor-mediated signalling 22/664 97/10654 8.753307521793193e-8 6.783813329389724e-7 3.8101167875799676e-7 7409/7311/4804/9138/26574/836/4615/8874/4790/5599/6453/7316/5584/3551/5970/3654/7189/835/8878/6654/7314/6233 22 Hepatitis_E_virus_genotype_1 R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 11/664 25/10654 1.0121144482943882e-7 7.791243437541364e-7 4.375938130386193e-7 1845/5598/1432/5518/5600/1848/1849/51231/5594/1846/5595 11 Hepatitis_E_virus_genotype_1 R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 9/664 16/10654 1.0356840249483071e-7 7.919530510771388e-7 4.4479903387253616e-7 7311/23118/6885/7316/10454/7189/7314/6233/257397 9 Hepatitis_E_virus_genotype_1 R-HSA-2262752 Cellular responses to stress 60/664 479/10654 1.3141055955857124e-7 9.981980914813326e-7 5.606361969316529e-7 1032/7295/2353/5925/7311/3303/5598/830/9883/367/1432/3725/57805/5684/5903/5601/3337/2908/4343/3320/6117/5602/8881/4790/5599/2033/5600/5606/5682/9448/7316/3312/112399/1029/4217/5707/6416/6774/7157/5970/1026/8086/832/29945/8697/5594/829/5609/9530/3308/7314/996/6233/7415/4193/5595/51434/51433/79902/23043 60 Hepatitis_E_virus_genotype_1 R-HSA-5654733 Negative regulation of FGFR4 signaling 12/664 31/10654 1.4642873653889826e-7 1.1049589526981336e-6 6.20598246272893e-7 7311/867/10253/5518/2253/7316/6714/5594/7314/6233/2885/5595 12 Hepatitis_E_virus_genotype_1 R-HSA-4086400 PCP/CE pathway 21/664 92/10654 1.5295750651460057e-7 1.1466814377271035e-6 6.440316063772656e-7 409/163/7311/1173/1213/5684/1211/161/160/5682/7316/1175/23002/5707/1856/8322/1212/4920/7314/6233/7474 21 Hepatitis_E_virus_genotype_1 R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 10/664 21/10654 1.556853747080948e-7 1.159552758377823e-6 6.512607609115109e-7 1147/11035/8517/4615/4790/3551/8737/5970/4791/28511 10 Hepatitis_E_virus_genotype_1 R-HSA-9009391 Extra-nuclear estrogen signaling 19/664 77/10654 1.6106027319722405e-7 1.191846021659458e-6 6.693982152577327e-7 5295/7514/2353/8503/5590/1956/857/5290/3320/2100/3265/1950/5747/2770/2771/2773/6714/5594/5595 19 Hepatitis_E_virus_genotype_1 R-HSA-2559580 Oxidative Stress Induced Senescence 25/664 125/10654 1.6228064520670572e-7 1.1931788464877656e-6 6.701467939710115e-7 1032/7295/2353/7311/1432/3725/5601/4343/5602/5599/5600/5606/9448/7316/1029/4217/6416/7157/5594/5609/7314/6233/4193/5595/23043 25 Hepatitis_E_virus_genotype_1 R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 9/664 17/10654 2.0793976334106947e-7 1.519152283772017e-6 8.532291998976501e-7 7311/23118/6885/7316/10454/7189/7314/6233/257397 9 Hepatitis_E_virus_genotype_1 R-HSA-3858494 Beta-catenin independent WNT signaling 27/664 146/10654 2.8040976090388515e-7 2.035632884536432e-6 1.143309618075801e-6 409/163/7311/27161/1173/3708/1213/5684/3710/1211/161/160/4343/6885/5682/7316/1175/23002/5707/1856/3709/8322/1212/4920/7314/6233/7474 27 Hepatitis_E_virus_genotype_1 R-HSA-1236394 Signaling by ERBB4 16/664 58/10654 2.947696201940025e-7 2.126419838757993e-6 1.194299950736376e-6 5295/7311/23118/51741/1956/5290/7316/3265/1950/2066/4734/6714/6654/7314/6233/2885 16 Hepatitis_E_virus_genotype_1 R-HSA-2559585 Oncogene Induced Senescence 12/664 33/10654 3.2792664355541083e-7 2.321801605913927e-6 1.3040357755419846e-6 1032/5925/7311/4343/7316/1029/7157/5594/7314/6233/4193/5595 12 Hepatitis_E_virus_genotype_1 R-HSA-5654726 Negative regulation of FGFR1 signaling 12/664 33/10654 3.2792664355541083e-7 2.321801605913927e-6 1.3040357755419846e-6 7311/867/10253/5518/2253/7316/6714/5594/7314/6233/2885/5595 12 Hepatitis_E_virus_genotype_1 R-HSA-8964043 Plasma lipoprotein clearance 12/664 33/10654 3.2792664355541083e-7 2.321801605913927e-6 1.3040357755419846e-6 163/3949/1173/1213/1211/161/160/338/26119/1175/335/7436 12 Hepatitis_E_virus_genotype_1 R-HSA-76009 Platelet Aggregation (Plug Formation) 13/664 39/10654 3.417350643043586e-7 2.4047246549515296e-6 1.3506093597304973e-6 2266/2243/2244/9564/2335/5770/5747/6850/2147/6714/6654/2885/1398 13 Hepatitis_E_virus_genotype_1 R-HSA-5654738 Signaling by FGFR2 18/664 73/10654 3.449596197321129e-7 2.4126139258093506e-6 1.355040354788531e-6 5295/7311/10817/867/10253/5518/5290/5335/2253/7316/3265/6714/5594/6654/7314/6233/2885/5595 18 Hepatitis_E_virus_genotype_1 R-HSA-8953897 Cellular responses to external stimuli 60/664 493/10654 3.6128756804552844e-7 2.5114960033225523e-6 1.410577299163403e-6 1032/7295/2353/5925/7311/3303/5598/830/9883/367/1432/3725/57805/5684/5903/5601/3337/2908/4343/3320/6117/5602/8881/4790/5599/2033/5600/5606/5682/9448/7316/3312/112399/1029/4217/5707/6416/6774/7157/5970/1026/8086/832/29945/8697/5594/829/5609/9530/3308/7314/996/6233/7415/4193/5595/51434/51433/79902/23043 60 Hepatitis_E_virus_genotype_1 R-HSA-195258 RHO GTPase Effectors 45/664 327/10654 3.8120901303269905e-7 2.6340164936656977e-6 1.4793907163982996e-6 10097/9055/7514/6093/1080/10092/7456/367/147179/1432/2017/8826/25/55920/5518/5590/5903/5347/999/5300/64837/5600/23002/5747/5058/4690/10093/10109/1856/998/5586/5062/10552/695/10094/4771/9212/6714/5594/8976/2885/5595/3798/10096/79902 45 Hepatitis_E_virus_genotype_1 R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 10/664 23/10654 4.5040510913766987e-7 3.0750872629815915e-6 1.727117335791065e-6 7311/8881/7316/29945/8697/7314/996/6233/51434/51433 10 Hepatitis_E_virus_genotype_1 R-HSA-373753 Nephrin family interactions 10/664 23/10654 4.5040510913766987e-7 3.0750872629815915e-6 1.727117335791065e-6 5295/8826/4868/5290/81/2534/4690/7827/8976/23607 10 Hepatitis_E_virus_genotype_1 R-HSA-2132295 MHC class II antigen presentation 24/664 123/10654 4.630180078233613e-7 3.1407571611509785e-6 1.7640007182346616e-6 163/830/9871/1173/1759/1213/1211/161/160/64837/9493/1175/9632/6456/7879/832/10427/829/1508/26052/29127/3798/1785/821 24 Hepatitis_E_virus_genotype_1 R-HSA-2871837 FCERI mediated NF-kB activation 19/664 82/10654 4.655001895341468e-7 3.1407571611509785e-6 1.7640007182346616e-6 1147/7311/23118/4067/5684/8517/4790/6885/5682/7316/3551/10454/5707/5970/8915/7189/7314/6233/257397 19 Hepatitis_E_virus_genotype_1 R-HSA-187687 Signalling to ERKs 12/664 34/10654 4.783146473027133e-7 3.1896912817221635e-6 1.7914844807176291e-6 1432/4914/5600/3265/6300/5603/6714/5594/6654/2885/5595/1398 12 Hepatitis_E_virus_genotype_1 R-HSA-5654727 Negative regulation of FGFR2 signaling 12/664 34/10654 4.783146473027133e-7 3.1896912817221635e-6 1.7914844807176291e-6 7311/867/10253/5518/2253/7316/6714/5594/7314/6233/2885/5595 12 Hepatitis_E_virus_genotype_1 R-HSA-114604 GPVI-mediated activation cascade 12/664 35/10654 6.869787721123657e-7 4.554708968860598e-6 2.5581442563600116e-6 5295/7409/8503/3932/5590/4067/5290/2534/10630/998/5336/6850 12 Hepatitis_E_virus_genotype_1 R-HSA-174824 Plasma lipoprotein assembly, remodeling, and clearance 17/664 69/10654 7.391945401199181e-7 4.872736422514633e-6 2.73676381460006e-6 163/3949/1173/1213/1211/161/160/338/26119/213/1175/335/345/5125/2/336/7436 17 Hepatitis_E_virus_genotype_1 R-HSA-388841 Costimulation by the CD28 family 17/664 70/10654 9.206009696450045e-7 6.03388178390183e-6 3.3889190581819115e-6 5295/7409/8503/3932/5518/4067/915/5290/917/2534/5058/9020/998/920/5062/6714/2885 17 Hepatitis_E_virus_genotype_1 R-HSA-2424491 DAP12 signaling 11/664 30/10654 9.302526435589149e-7 6.062498762284519e-6 3.404991733600813e-6 5295/3932/5290/5335/2534/3265/5336/6850/695/6654/2885 11 Hepatitis_E_virus_genotype_1 R-HSA-354194 GRB2:SOS provides linkage to MAPK signaling for Integrins 8/664 15/10654 9.498355798441359e-7 6.120569719557437e-6 3.437607184296932e-6 2266/2243/2244/2335/5747/6714/6654/2885 8 Hepatitis_E_virus_genotype_1 R-HSA-372708 p130Cas linkage to MAPK signaling for integrins 8/664 15/10654 9.498355798441359e-7 6.120569719557437e-6 3.437607184296932e-6 2266/2243/2244/9564/2335/5747/6714/1398 8 Hepatitis_E_virus_genotype_1 R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 21/664 102/10654 9.600909488318142e-7 6.152091163743525e-6 3.4553111478098817e-6 7124/1147/330/7311/7132/329/7187/5684/7186/10913/5682/7316/8718/5707/9020/356/8742/7133/4791/7314/6233 21 Hepatitis_E_virus_genotype_1 R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 12/664 36/10654 9.725966764160584e-7 6.163361258835464e-6 3.461640976834125e-6 2266/409/8826/2243/2244/2335/408/3265/5894/6714/5594/5595 12 Hepatitis_E_virus_genotype_1 R-HSA-6804757 Regulation of TP53 Degradation 12/664 36/10654 9.725966764160584e-7 6.163361258835464e-6 3.461640976834125e-6 7311/5518/117584/1616/9099/7316/1029/80196/7157/7314/6233/4193 12 Hepatitis_E_virus_genotype_1 R-HSA-114608 Platelet degranulation 24/664 129/10654 1.1465520034103682e-6 7.155793751564594e-6 4.01903893539901e-6 5004/2266/3082/928/3920/226/2243/197/2244/5005/81/3699/7018/2335/213/5340/1950/335/350/54495/2/967/139322/3700 24 Hepatitis_E_virus_genotype_1 R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 10/664 25/10654 1.1479215782806324e-6 7.155793751564594e-6 4.01903893539901e-6 7311/8881/7316/29945/8697/7314/996/6233/51434/51433 10 Hepatitis_E_virus_genotype_1 R-HSA-9006335 Signaling by Erythropoietin 10/664 25/10654 1.1479215782806324e-6 7.155793751564594e-6 4.01903893539901e-6 5295/7409/5293/4067/5290/5335/3265/5336/6654/2885 10 Hepatitis_E_virus_genotype_1 R-HSA-167044 Signalling to RAS 9/664 20/10654 1.2119827776825702e-6 7.514293221631935e-6 4.220389530251682e-6 1432/4914/5600/3265/6300/5603/6714/6654/2885 9 Hepatitis_E_virus_genotype_1 R-HSA-6806003 Regulation of TP53 Expression and Degradation 12/664 37/10654 1.3586311433004443e-6 8.378225383686073e-6 4.705615504809689e-6 7311/5518/117584/1616/9099/7316/1029/80196/7157/7314/6233/4193 12 Hepatitis_E_virus_genotype_1 R-HSA-3700989 Transcriptional Regulation by TP53 47/664 365/10654 1.4644212457485389e-6 8.982305715901467e-6 5.0448961576026225e-6 9150/9656/355/7295/2353/7311/55367/27161/1432/3725/5518/117584/1616/9099/843/5300/5983/4343/6117/6794/2033/1327/5600/10128/7316/85456/8738/29883/1029/28996/1351/80196/637/7157/10397/8795/1026/8626/9212/25904/835/7314/6233/7832/4193/8797/6878 47 Hepatitis_E_virus_genotype_1 R-HSA-451927 Interleukin-2 family signaling 13/664 44/10654 1.6339318514888284e-6 9.968722519455777e-6 5.59891541495612e-6 5295/8503/3932/5293/2185/3635/3636/5290/6774/6850/6772/6654/2885 13 Hepatitis_E_virus_genotype_1 R-HSA-186797 Signaling by PDGF 15/664 58/10654 1.7093792841198259e-6 1.0373852057594923e-5 5.8264557052705844e-6 5295/5159/5921/5290/9564/5335/3265/5340/4690/6774/6772/6714/6654/2885/1398 15 Hepatitis_E_virus_genotype_1 R-HSA-3928665 EPH-ephrin mediated repulsion of cells 14/664 51/10654 1.740593278477027e-6 1.050768679164816e-5 5.901623747523217e-6 163/1173/1759/1213/4067/1211/161/160/2534/1175/8218/1969/1212/6714 14 Hepatitis_E_virus_genotype_1 R-HSA-1433559 Regulation of KIT signaling 8/664 16/10654 1.7961027571934526e-6 1.0729843033858802e-5 6.0263974090043485e-6 867/3932/4067/2534/3815/6714/6654/2885 8 Hepatitis_E_virus_genotype_1 R-HSA-205043 NRIF signals cell death from the nucleus 8/664 16/10654 1.7961027571934526e-6 1.0729843033858802e-5 6.0263974090043485e-6 7311/4804/5599/7316/7189/8878/7314/6233 8 Hepatitis_E_virus_genotype_1 R-HSA-5621575 CD209 (DC-SIGN) signaling 9/664 21/10654 2.004205829913439e-6 1.1911005631661734e-5 6.689795298102126e-6 4067/4790/2534/2033/3265/5058/5970/5062/5894 9 Hepatitis_E_virus_genotype_1 R-HSA-5689880 Ub-specific processing proteases 33/664 220/10654 2.105669214405783e-6 1.2449497881048625e-5 6.992238519893322e-6 409/1080/330/7311/367/329/5684/7046/6502/9099/27005/8517/9146/7186/6885/408/51651/5682/7316/1540/25862/10454/5707/8737/7157/154/10254/7189/7375/4609/7314/6233/4193 33 Hepatitis_E_virus_genotype_1 R-HSA-2029481 FCGR activation 7/664 12/10654 2.128454741923161e-6 1.245580402543809e-5 6.995780354763559e-6 4067/917/2534/3055/6850/6714/2268 7 Hepatitis_E_virus_genotype_1 R-HSA-389359 CD28 dependent Vav1 pathway 7/664 12/10654 2.128454741923161e-6 1.245580402543809e-5 6.995780354763559e-6 7409/3932/2534/5058/998/5062/2885 7 Hepatitis_E_virus_genotype_1 R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 24/664 134/10654 2.32535521854913e-6 1.3538997135410416e-5 7.604153853871588e-6 5004/2266/3082/928/3920/226/2243/197/2244/5005/81/3699/7018/2335/213/5340/1950/335/350/54495/2/967/139322/3700 24 Hepatitis_E_virus_genotype_1 R-HSA-164952 The role of Nef in HIV-1 replication and disease pathogenesis 10/664 27/10654 2.6430522563494013e-6 1.531101483854931e-5 8.599404470419106e-6 163/1173/3932/161/160/2534/1175/920/5062/3055 10 Hepatitis_E_virus_genotype_1 R-HSA-2871809 FCERI mediated Ca+2 mobilization 11/664 33/10654 2.7739771608602646e-6 1.598870253018454e-5 8.980026566762666e-6 7409/3708/4067/3710/5335/5336/6850/695/3709/6654/2885 11 Hepatitis_E_virus_genotype_1 R-HSA-9613829 Chaperone Mediated Autophagy 9/664 22/10654 3.2051176061568304e-6 1.8381349471309424e-5 1.0323852499831476e-5 1080/7311/3920/3320/7316/3312/11315/7314/6233 9 Hepatitis_E_virus_genotype_1 R-HSA-5674135 MAP2K and MAPK activation 12/664 40/10654 3.445798719270931e-6 1.96633389602177e-5 1.1043879634426865e-5 2266/409/8826/2243/2244/2335/408/3265/5894/6714/5594/5595 12 Hepatitis_E_virus_genotype_1 R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 21/664 110/10654 3.471654040727538e-6 1.971280784512122e-5 1.1071663746353588e-5 1032/2353/7311/5598/3725/8881/4790/7316/1029/6774/5970/1026/29945/8697/5594/7314/996/6233/5595/51434/51433 21 Hepatitis_E_virus_genotype_1 R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 11/664 34/10654 3.871902710822582e-6 2.1877203986766014e-5 1.2287293020603684e-5 7128/7311/7187/7706/5300/8887/7316/1540/57506/7314/6233 11 Hepatitis_E_virus_genotype_1 R-HSA-162909 Host Interactions of HIV factors 23/664 129/10654 4.080000794404501e-6 2.2940004466578244e-5 1.2884213034961581e-5 7514/163/7311/11168/9883/1173/3932/5684/5903/161/160/2534/5682/7316/1175/5707/920/5062/3055/8086/7314/6233/79902 23 Hepatitis_E_virus_genotype_1 R-HSA-112409 RAF-independent MAPK1/3 activation 9/664 23/10654 4.976004211383441e-6 2.784135039247223e-5 1.5637045326658106e-5 1843/1844/1850/1852/1848/1849/5594/1846/5595 9 Hepatitis_E_virus_genotype_1 R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 15/664 63/10654 5.240687701817976e-6 2.9179945601869996e-5 1.6388864964295358e-5 1147/7311/11035/8517/4615/4790/2033/7316/3551/8737/5970/4791/7314/28511/6233 15 Hepatitis_E_virus_genotype_1 R-HSA-190236 Signaling by FGFR 18/664 87/10654 5.2963767797229295e-6 2.934755635914106e-5 1.6483003250396305e-5 5295/7311/10817/867/10253/5518/5290/5335/2253/7316/3265/6714/5594/6654/7314/6233/2885/5595 18 Hepatitis_E_virus_genotype_1 R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 16/664 72/10654 6.68367201542478e-6 3.6856595200443376e-5 2.0700441667206302e-5 7311/5684/6502/5347/8881/5682/7316/5707/29945/8697/9212/7314/996/6233/51434/51433 16 Hepatitis_E_virus_genotype_1 R-HSA-5687128 MAPK6/MAPK4 signaling 18/664 89/10654 7.421121942769187e-6 4.072740128400123e-5 2.2874473074665035e-5 7514/7311/27161/3725/5684/3337/4343/5682/7316/5058/5707/998/5062/5597/896/4609/7314/6233 18 Hepatitis_E_virus_genotype_1 R-HSA-5260271 Diseases of Immune System 9/664 24/10654 7.5240642232733824e-6 4.09009557540027e-5 2.2971949636534354e-5 1147/7187/8517/4615/4790/3551/5970/695/4791 9 Hepatitis_E_virus_genotype_1 R-HSA-5602358 Diseases associated with the TLR signaling cascade 9/664 24/10654 7.5240642232733824e-6 4.09009557540027e-5 2.2971949636534354e-5 1147/7187/8517/4615/4790/3551/5970/695/4791 9 Hepatitis_E_virus_genotype_1 R-HSA-373752 Netrin-1 signaling 13/664 50/10654 7.888117858633665e-6 4.2677694263456666e-5 2.3969851685619677e-5 1432/5335/5599/2534/5600/5747/5058/4690/6300/5603/998/6714/8976 13 Hepatitis_E_virus_genotype_1 R-HSA-110320 Translesion Synthesis by POLH 8/664 19/10654 8.9173180863011e-6 4.801954856801578e-5 2.697009473099221e-5 7311/5983/6117/7316/55666/7314/6233/7415 8 Hepatitis_E_virus_genotype_1 R-HSA-5339562 Uptake and actions of bacterial toxins 10/664 31/10654 1.1062903063314997e-5 5.8999579615096684e-5 3.313700979620903e-5 127833/84168/928/10015/6857/3320/5606/6416/5609/6844 10 Hepatitis_E_virus_genotype_1 R-HSA-2029485 Role of phospholipids in phagocytosis 9/664 25/10654 1.1110644461081852e-5 5.8999579615096684e-5 3.313700979620903e-5 5295/3708/3710/5290/917/5335/5336/6850/3709 9 Hepatitis_E_virus_genotype_1 R-HSA-9006115 Signaling by NTRK2 (TRKB) 9/664 25/10654 1.1110644461081852e-5 5.8999579615096684e-5 3.313700979620903e-5 5295/10817/5290/5335/2534/3265/6714/6654/2885 9 Hepatitis_E_virus_genotype_1 R-HSA-5655302 Signaling by FGFR1 in disease 11/664 38/10654 1.2947379210131083e-5 6.843614725355e-5 3.8437041361145884e-5 5295/5290/5335/2253/3265/6774/6772/9530/6654/2885/613 11 Hepatitis_E_virus_genotype_1 R-HSA-204998 Cell death signalling via NRAGE, NRIF and NADE 16/664 76/10654 1.3918578605790582e-5 7.323215440753119e-5 4.1130710317449724e-5 7409/7311/4804/9138/26574/836/8874/5599/6453/7316/7189/835/8878/6654/7314/6233 16 Hepatitis_E_virus_genotype_1 R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 7/664 15/10654 1.4653696310162715e-5 7.6747898026286e-5 4.310532151799847e-5 7311/4615/7316/3654/7189/7314/6233 7 Hepatitis_E_virus_genotype_1 R-HSA-2173789 TGF-beta receptor signaling activates SMADs 10/664 32/10654 1.5201210370082957e-5 7.92535831567507e-5 4.451263515067355e-5 7514/7048/7311/23327/867/7046/7316/7314/6233/9372 10 Hepatitis_E_virus_genotype_1 R-HSA-1660499 Synthesis of PIPs at the plasma membrane 13/664 53/10654 1.572227234466684e-5 8.159930488385913e-5 4.583010562008148e-5 5295/8503/5293/3635/3636/5290/5868/54477/5286/51552/8871/4952/8867 13 Hepatitis_E_virus_genotype_1 R-HSA-2173788 Downregulation of TGF-beta receptor signaling 9/664 26/10654 1.6059999346426263e-5 8.297666328986903e-5 4.660369653870495e-5 7514/7048/7311/23327/7046/7316/7314/6233/9372 9 Hepatitis_E_virus_genotype_1 R-HSA-376172 DSCAM interactions 6/664 11/10654 2.0204030900707264e-5 1.0345546179960372e-4 5.8105577590379916e-5 1432/5599/5600/5058/6300/5603 6 Hepatitis_E_virus_genotype_1 R-HSA-5655291 Signaling by FGFR4 in disease 6/664 11/10654 2.0204030900707264e-5 1.0345546179960372e-4 5.8105577590379916e-5 5295/5290/5335/3265/6654/2885 6 Hepatitis_E_virus_genotype_1 R-HSA-5218921 VEGFR2 mediated cell proliferation 8/664 21/10654 2.1469594422590377e-5 1.0783294523595397e-4 6.056418343908947e-5 3708/5921/5590/3710/5335/3265/3709/6714 8 Hepatitis_E_virus_genotype_1 R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 12/664 47/10654 2.152898383525149e-5 1.0783294523595397e-4 6.056418343908947e-5 2266/409/8826/2243/2244/2335/408/3265/5894/6714/5594/5595 12 Hepatitis_E_virus_genotype_1 R-HSA-6802949 Signaling by RAS mutants 12/664 47/10654 2.152898383525149e-5 1.0783294523595397e-4 6.056418343908947e-5 2266/409/8826/2243/2244/2335/408/3265/5894/6714/5594/5595 12 Hepatitis_E_virus_genotype_1 R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 12/664 47/10654 2.152898383525149e-5 1.0783294523595397e-4 6.056418343908947e-5 2266/409/8826/2243/2244/2335/408/3265/5894/6714/5594/5595 12 Hepatitis_E_virus_genotype_1 R-HSA-9649948 Signaling downstream of RAS mutants 12/664 47/10654 2.152898383525149e-5 1.0783294523595397e-4 6.056418343908947e-5 2266/409/8826/2243/2244/2335/408/3265/5894/6714/5594/5595 12 Hepatitis_E_virus_genotype_1 R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 27/664 182/10654 2.1677503065538417e-5 1.081047652877068e-4 6.071685069157672e-5 9656/9883/367/10521/5903/1616/8517/2908/3183/7068/6117/5465/2033/1029/28996/11315/7157/5970/3190/8086/1786/7329/4791/9212/4193/8554/79902 27 Hepatitis_E_virus_genotype_1 R-HSA-110312 Translesion synthesis by REV1 7/664 16/10654 2.465404685136096e-5 1.2136562977901725e-4 6.816479183660678e-5 7311/5983/6117/7316/10459/7314/6233 7 Hepatitis_E_virus_genotype_1 R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 7/664 16/10654 2.465404685136096e-5 1.2136562977901725e-4 6.816479183660678e-5 7048/7311/5590/7046/7316/7314/6233 7 Hepatitis_E_virus_genotype_1 R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 7/664 16/10654 2.465404685136096e-5 1.2136562977901725e-4 6.816479183660678e-5 5295/4067/5290/2534/6850/6654/2885 7 Hepatitis_E_virus_genotype_1 R-HSA-8853659 RET signaling 11/664 41/10654 2.8630044029191536e-5 1.403361559892423e-4 7.881955441234919e-5 5295/8503/5598/9260/5293/1796/5290/5335/6714/6654/2885 11 Hepatitis_E_virus_genotype_1 R-HSA-210990 PECAM1 interactions 6/664 12/10654 3.8279607059491384e-5 1.8526037678158908e-4 1.0405116375931038e-4 3932/4067/3635/5335/2534/6714 6 Hepatitis_E_virus_genotype_1 R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 6/664 12/10654 3.8279607059491384e-5 1.8526037678158908e-4 1.0405116375931038e-4 55367/843/8738/7157/8626/835 6 Hepatitis_E_virus_genotype_1 R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 6/664 12/10654 3.8279607059491384e-5 1.8526037678158908e-4 1.0405116375931038e-4 7311/7187/7316/7314/6233/10010 6 Hepatitis_E_virus_genotype_1 R-HSA-2990846 SUMOylation 27/664 188/10654 3.9032269761044396e-5 1.88109300066882e-4 1.0565125649606004e-4 9656/9883/367/10521/5903/1616/8517/2908/3183/7068/6117/5465/2033/1029/28996/11315/7157/5970/3190/8086/1786/7329/4791/9212/4193/8554/79902 27 Hepatitis_E_virus_genotype_1 R-HSA-5655862 Translesion synthesis by POLK 7/664 17/10654 3.966641740999241e-5 1.8878581232058627e-4 1.0603121840976353e-4 7311/5983/6117/7316/10459/7314/6233 7 Hepatitis_E_virus_genotype_1 R-HSA-5656121 Translesion synthesis by POLI 7/664 17/10654 3.966641740999241e-5 1.8878581232058627e-4 1.0603121840976353e-4 7311/5983/6117/7316/10459/7314/6233 7 Hepatitis_E_virus_genotype_1 R-HSA-9034015 Signaling by NTRK3 (TRKC) 7/664 17/10654 3.966641740999241e-5 1.8878581232058627e-4 1.0603121840976353e-4 5295/5290/5335/3265/6714/6654/2885 7 Hepatitis_E_virus_genotype_1 R-HSA-8863795 Downregulation of ERBB2 signaling 9/664 29/10654 4.346573649436918e-5 2.0601322214479936e-4 1.1570696274273137e-4 7311/1956/3320/7316/1950/2066/10193/7314/6233 9 Hepatitis_E_virus_genotype_1 R-HSA-2172127 DAP12 interactions 11/664 43/10654 4.648982706836483e-5 2.19439636409113e-4 1.2324788462568458e-4 5295/3932/5290/5335/2534/3265/5336/6850/695/6654/2885 11 Hepatitis_E_virus_genotype_1 R-HSA-1169091 Activation of NF-kappaB in B cells 14/664 67/10654 5.201971652526229e-5 2.4353720348765652e-4 1.3678224065933632e-4 1147/7311/5684/8517/4790/6885/5682/7316/3551/5707/5970/8915/7314/6233 14 Hepatitis_E_virus_genotype_1 R-HSA-6802952 Signaling by BRAF and RAF fusions 14/664 67/10654 5.201971652526229e-5 2.4353720348765652e-4 1.3678224065933632e-4 2266/409/8826/2243/2244/9444/2335/408/3265/10142/5894/6714/5594/5595 14 Hepatitis_E_virus_genotype_1 R-HSA-983169 Class I MHC mediated antigen processing & presentation 43/664 371/10654 5.6226297502974025e-5 2.621608261622407e-4 1.4724216547633764e-4 7327/1147/7311/23327/9871/26091/23295/9341/10293/5684/6502/8517/7336/868/4615/10616/9320/27246/8881/9666/5682/54778/7316/3551/8673/80196/114907/5707/9632/90678/695/4734/29945/8697/10427/10193/55658/7314/996/6233/51434/51433/821 43 Hepatitis_E_virus_genotype_1 R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 11/664 44/10654 5.8543555232265226e-5 2.7186015324456766e-4 1.5268977541933227e-4 355/55367/843/8738/637/7157/10397/8795/8626/835/8797 11 Hepatitis_E_virus_genotype_1 R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 7/664 18/10654 6.143433547453038e-5 2.84133801569703e-4 1.5958324834640324e-4 5598/1956/3265/5594/6654/2885/5595 7 Hepatitis_E_virus_genotype_1 R-HSA-171007 p38MAPK events 6/664 13/10654 6.735038629582737e-5 3.1024455052736544e-4 1.7424830443054891e-4 1432/5600/3265/6300/5603/6714 6 Hepatitis_E_virus_genotype_1 R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 16/664 86/10654 6.931182444854784e-5 3.1673570773898163e-4 1.7789405142592277e-4 7311/5684/6502/5347/8881/5682/7316/5707/29945/8697/9212/7314/996/6233/51434/51433 16 Hepatitis_E_virus_genotype_1 R-HSA-453276 Regulation of mitotic cell cycle 16/664 86/10654 6.931182444854784e-5 3.1673570773898163e-4 1.7789405142592277e-4 7311/5684/6502/5347/8881/5682/7316/5707/29945/8697/9212/7314/996/6233/51434/51433 16 Hepatitis_E_virus_genotype_1 R-HSA-5654708 Downstream signaling of activated FGFR3 8/664 25/10654 9.130377415060238e-5 4.155770990108767e-4 2.3340814444514896e-4 5295/10817/5290/5335/2253/3265/6654/2885 8 Hepatitis_E_virus_genotype_1 R-HSA-176412 Phosphorylation of the APC/C 7/664 19/10654 9.206926228433073e-5 4.157615899217612e-4 2.3351176343974477e-4 5347/8881/29945/8697/996/51434/51433 7 Hepatitis_E_virus_genotype_1 R-HSA-6804760 Regulation of TP53 Activity through Methylation 7/664 19/10654 9.206926228433073e-5 4.157615899217612e-4 2.3351176343974477e-4 7311/2033/7316/7157/7314/6233/4193 7 Hepatitis_E_virus_genotype_1 R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 10/664 39/10654 1.0066139662750557e-4 4.527789095362702e-4 2.543024756905404e-4 7311/7706/5983/6117/7316/55666/10459/7314/6233/7415 10 Hepatitis_E_virus_genotype_1 R-HSA-6802957 Oncogenic MAPK signaling 14/664 71/10654 1.014989942035689e-4 4.547630716855216e-4 2.554168768609547e-4 2266/409/8826/2243/2244/9444/2335/408/3265/10142/5894/6714/5594/5595 14 Hepatitis_E_virus_genotype_1 R-HSA-3371556 Cellular response to heat stress 16/664 89/10654 1.0626268825872309e-4 4.742540989601377e-4 2.6636397794117773e-4 3303/9883/57805/5903/3337/3320/6117/2033/3312/8086/5594/9530/3308/7415/5595/79902 16 Hepatitis_E_virus_genotype_1 R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 13/664 63/10654 1.0980885955431124e-4 4.881812477085077e-4 2.7418613646364127e-4 7311/5684/8881/5682/7316/5707/29945/8697/7314/996/6233/51434/51433 13 Hepatitis_E_virus_genotype_1 R-HSA-418885 DCC mediated attractive signaling 6/664 14/10654 1.1166925504068726e-4 4.936534057264761e-4 2.772595643597516e-4 2534/5747/4690/998/6714/8976 6 Hepatitis_E_virus_genotype_1 R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 18/664 108/10654 1.1190051045238342e-4 4.936534057264761e-4 2.772595643597516e-4 5295/3082/7124/2353/5743/3726/3320/2335/3312/6774/7157/356/1026/3586/7133/3553/6772/4609 18 Hepatitis_E_virus_genotype_1 R-HSA-1169408 ISG15 antiviral mechanism 14/664 72/10654 1.1891500417634287e-4 5.22588160115959e-4 2.935107181122075e-4 7311/9883/5903/7706/5300/5335/7316/8086/4734/6772/7314/6233/5595/79902 14 Hepatitis_E_virus_genotype_1 R-HSA-373760 L1CAM interactions 19/664 119/10654 1.316326438718587e-4 5.762696279428318e-4 3.236608198054542e-4 163/1173/1759/1213/1956/1211/161/160/1808/8986/3312/1175/5058/6456/6714/5594/26052/5595/1785 19 Hepatitis_E_virus_genotype_1 R-HSA-202433 Generation of second messenger molecules 9/664 33/10654 1.3365485037803785e-4 5.825255356718254e-4 3.271744393439703e-4 3932/915/917/5335/7408/5058/4690/920/5062 9 Hepatitis_E_virus_genotype_1 R-HSA-164938 Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 7/664 20/10654 1.3407736828017605e-4 5.825255356718254e-4 3.271744393439703e-4 163/1173/3932/161/160/1175/920 7 Hepatitis_E_virus_genotype_1 R-HSA-73893 DNA Damage Bypass 11/664 48/10654 1.372734408585201e-4 5.941608930744248e-4 3.337094173005534e-4 7311/7706/5983/6117/7316/55666/56852/10459/7314/6233/7415 11 Hepatitis_E_virus_genotype_1 R-HSA-170834 Signaling by TGF-beta Receptor Complex 14/664 73/10654 1.388629464697326e-4 5.987812015067041e-4 3.3630440537980356e-4 7514/7048/7311/23327/867/3726/5590/7046/54778/7316/4609/7314/6233/9372 14 Hepatitis_E_virus_genotype_1 R-HSA-5633007 Regulation of TP53 Activity 23/664 160/10654 1.4162284185534308e-4 6.083947550864364e-4 3.4170384078639846e-4 7311/1432/5518/117584/1616/9099/5300/5983/6117/6794/2033/5600/7316/1029/28996/80196/7157/8626/9212/7314/6233/4193/6878 23 Hepatitis_E_virus_genotype_1 R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 15/664 83/10654 1.630676288225516e-4 6.979051129084577e-4 3.9197717533150664e-4 1147/7311/5684/8517/4790/6885/5682/7316/3265/3551/5707/5970/8915/7314/6233 15 Hepatitis_E_virus_genotype_1 R-HSA-5654716 Downstream signaling of activated FGFR4 8/664 27/10654 1.676831271886662e-4 7.123427662422227e-4 4.000860578536597e-4 5295/10817/5290/5335/2253/3265/6654/2885 8 Hepatitis_E_virus_genotype_1 R-HSA-912526 Interleukin receptor SHC signaling 8/664 27/10654 1.676831271886662e-4 7.123427662422227e-4 4.000860578536597e-4 5295/8503/5293/3635/3636/5290/6654/2885 8 Hepatitis_E_virus_genotype_1 R-HSA-8853334 Signaling by FGFR3 fusions in cancer 5/664 10/10654 1.7943566869180059e-4 7.566643823143208e-4 4.2497921532268565e-4 5295/5290/3265/6654/2885 5 Hepatitis_E_virus_genotype_1 R-HSA-8875656 MET receptor recycling 5/664 10/10654 1.7943566869180059e-4 7.566643823143208e-4 4.2497921532268565e-4 3082/23163/4233/2885/1398 5 Hepatitis_E_virus_genotype_1 R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 13/664 67/10654 2.1137890031254126e-4 8.881010939871239e-4 4.988004125362455e-4 7311/5684/8881/5682/7316/5707/29945/8697/7314/996/6233/51434/51433 13 Hepatitis_E_virus_genotype_1 R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 14/664 76/10654 2.170243034293441e-4 9.084922482972909e-4 5.102530683778663e-4 7311/5684/5347/8881/5682/7316/5707/29945/8697/7314/996/6233/51434/51433 14 Hepatitis_E_virus_genotype_1 R-HSA-5655332 Signaling by FGFR3 in disease 7/664 22/10654 2.6433616975822896e-4 0.0010985274880894514 6.169860255226397e-4 5295/5290/5335/2253/3265/6654/2885 7 Hepatitis_E_virus_genotype_1 R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 7/664 22/10654 2.6433616975822896e-4 0.0010985274880894514 6.169860255226397e-4 5295/5290/5335/2253/3265/6654/2885 7 Hepatitis_E_virus_genotype_1 R-HSA-1963640 GRB2 events in ERBB2 signaling 6/664 16/10654 2.6736164260017633e-4 0.001103107208857562 6.195582176119195e-4 1956/3265/1950/2066/6654/2885 6 Hepatitis_E_virus_genotype_1 R-HSA-1963642 PI3K events in ERBB2 signaling 6/664 16/10654 2.6736164260017633e-4 0.001103107208857562 6.195582176119195e-4 5295/1956/5290/1950/2066/2885 6 Hepatitis_E_virus_genotype_1 R-HSA-3371453 Regulation of HSF1-mediated heat shock response 13/664 69/10654 2.87015391997707e-4 0.0011799521671016842 6.627180528300196e-4 3303/9883/57805/5903/3337/6117/3312/8086/5594/9530/3308/5595/79902 13 Hepatitis_E_virus_genotype_1 R-HSA-8851805 MET activates RAS signaling 5/664 11/10654 3.1212870018437907e-4 0.0012786129253981528 7.181306936572933e-4 3082/3265/4233/6654/2885 5 Hepatitis_E_virus_genotype_1 R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 15/664 88/10654 3.1829667505600006e-4 0.001299239452986591 7.297155464853794e-4 7514/7311/3303/1432/26986/5684/7538/5600/5682/7316/3312/5707/7314/6233/1994 15 Hepatitis_E_virus_genotype_1 R-HSA-109606 Intrinsic Pathway for Apoptosis 11/664 53/10654 3.48337387241047e-4 0.001416819089239294 7.957539417376663e-4 841/836/331/5599/1029/637/6774/7157/8626/5594/5595 11 Hepatitis_E_virus_genotype_1 R-HSA-453279 Mitotic G1-G1/S phases 21/664 149/10654 3.584441988835142e-4 0.0014527756046621584 8.159488551858312e-4 1032/5925/7311/25/5518/4067/5684/6502/6117/5682/7316/4174/1029/1163/5707/1026/896/6714/4609/7314/6233 21 Hepatitis_E_virus_genotype_1 R-HSA-5654696 Downstream signaling of activated FGFR2 8/664 30/10654 3.742624016118662e-4 0.0015115456853831357 8.489569673330694e-4 5295/10817/5290/5335/2253/3265/6654/2885 8 Hepatitis_E_virus_genotype_1 R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 14/664 80/10654 3.780425841406722e-4 0.001516135818214514 8.515350073393131e-4 7311/9883/5903/7706/5300/5335/7316/8086/4734/6772/7314/6233/5595/79902 14 Hepatitis_E_virus_genotype_1 R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 14/664 80/10654 3.780425841406722e-4 0.001516135818214514 8.515350073393131e-4 7311/5684/5347/8881/5682/7316/5707/29945/8697/7314/996/6233/51434/51433 14 Hepatitis_E_virus_genotype_1 R-HSA-180292 GAB1 signalosome 6/664 17/10654 3.915590381584587e-4 0.001559438252665806 8.758557432491839e-4 5295/1956/5290/1950/6714/2885 6 Hepatitis_E_virus_genotype_1 R-HSA-416993 Trafficking of GluR2-containing AMPA receptors 6/664 17/10654 3.915590381584587e-4 0.001559438252665806 8.758557432491839e-4 163/1173/161/160/1175/4905 6 Hepatitis_E_virus_genotype_1 R-HSA-69052 Switching of origins to a post-replicative state 15/664 90/10654 4.0914624527198067e-4 0.001623843402515439 9.120287820304214e-4 7311/5684/6502/8881/5682/7316/4174/5707/29945/8697/7314/996/6233/51434/51433 15 Hepatitis_E_virus_genotype_1 R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 13/664 72/10654 4.4316865294539255e-4 0.0017467850341180938 9.810787325106902e-4 7311/5684/8881/5682/7316/5707/29945/8697/7314/996/6233/51434/51433 13 Hepatitis_E_virus_genotype_1 R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 13/664 72/10654 4.4316865294539255e-4 0.0017467850341180938 9.810787325106902e-4 7311/5684/8881/5682/7316/5707/29945/8697/7314/996/6233/51434/51433 13 Hepatitis_E_virus_genotype_1 R-HSA-1839124 FGFR1 mutant receptor activation 8/664 31/10654 4.7724782904207054e-4 0.001868270511642508 0.0010493108366220485 5295/5290/2253/6774/6772/9530/2885/613 8 Hepatitis_E_virus_genotype_1 R-HSA-5654687 Downstream signaling of activated FGFR1 8/664 31/10654 4.7724782904207054e-4 0.001868270511642508 0.0010493108366220485 5295/10817/5290/5335/2253/3265/6654/2885 8 Hepatitis_E_virus_genotype_1 R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 7/664 24/10654 4.808397655751831e-4 0.0018759292895059014 0.001053612375696427 7514/2353/1956/1950/5747/5594/5595 7 Hepatitis_E_virus_genotype_1 R-HSA-8941858 Regulation of RUNX3 expression and activity 11/664 55/10654 4.8804614736890604e-4 0.0018975895967191026 0.0010657778490268351 7311/5684/2033/5682/7316/1029/5707/6714/7314/6233/4193 11 Hepatitis_E_virus_genotype_1 R-HSA-5689877 Josephin domain DUBs 5/664 12/10654 5.077351952735836e-4 0.001959528472313229 0.0011005657092237838 7311/7316/7314/6233/7415 5 Hepatitis_E_virus_genotype_1 R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 5/664 12/10654 5.077351952735836e-4 0.001959528472313229 0.0011005657092237838 355/7157/8795/8626/8797 5 Hepatitis_E_virus_genotype_1 R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 13/664 73/10654 5.091015560151197e-4 0.001959528472313229 0.0011005657092237838 7311/5684/8881/5682/7316/5707/29945/8697/7314/996/6233/51434/51433 13 Hepatitis_E_virus_genotype_1 R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 15/664 92/10654 5.213669697520034e-4 0.002000026469249324 0.0011233113377511921 7311/1432/5300/5983/6117/6794/5600/7316/28996/7157/9212/7314/6233/4193/6878 15 Hepatitis_E_virus_genotype_1 R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 6/664 18/10654 5.566213895004225e-4 0.0021109704203658795 0.0011856228121542864 5295/5290/6774/6772/2885/613 6 Hepatitis_E_virus_genotype_1 R-HSA-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 6/664 18/10654 5.566213895004225e-4 0.0021109704203658795 0.0011856228121542864 330/329/7187/7186/9020/8742 6 Hepatitis_E_virus_genotype_1 R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 6/664 18/10654 5.566213895004225e-4 0.0021109704203658795 0.0011856228121542864 7311/7187/7316/7314/6233/10010 6 Hepatitis_E_virus_genotype_1 R-HSA-1236974 ER-Phagosome pathway 14/664 83/10654 5.576495530696264e-4 0.0021109704203658795 0.0011856228121542864 1147/7311/9341/5684/8517/4615/5682/7316/3551/8673/5707/695/7314/6233 14 Hepatitis_E_virus_genotype_1 R-HSA-1483255 PI Metabolism 14/664 84/10654 6.317134499659551e-4 0.002377960341568876 0.0013355772303401572 5295/8503/5293/3635/3636/5290/54545/5868/54477/5286/51552/8871/4952/8867 14 Hepatitis_E_virus_genotype_1 R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus 7/664 25/10654 6.323259844625172e-4 0.002377960341568876 0.0013355772303401572 7311/1956/7316/1950/4904/7314/6233 7 Hepatitis_E_virus_genotype_1 R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 13/664 75/10654 6.660929077352897e-4 0.0024967600169031935 0.0014023008583900836 7311/5684/8881/5682/7316/5707/29945/8697/7314/996/6233/51434/51433 13 Hepatitis_E_virus_genotype_1 R-HSA-8939211 ESR-mediated signaling 27/664 223/10654 6.811926940271272e-4 0.002545042410583436 0.001429418579614613 5295/7514/2353/8503/27161/3725/2354/5590/1956/857/5290/4343/3320/2033/2100/3265/1950/5747/7031/2770/2066/2771/2773/6714/5594/4609/5595 27 Hepatitis_E_virus_genotype_1 R-HSA-1632852 Macroautophagy 15/664 95/10654 7.384817693696257e-4 0.0027446597529655037 0.0015415333077730359 7311/51652/29082/91782/128866/79643/7316/3312/25978/27243/92421/6714/8878/7314/6233 15 Hepatitis_E_virus_genotype_1 R-HSA-157858 Gap junction trafficking and regulation 10/664 49/10654 7.39407030223488e-4 0.0027446597529655037 0.0015415333077730359 2697/1173/1759/1213/1211/8218/1212/6714/1601/1785 10 Hepatitis_E_virus_genotype_1 R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 6/664 19/10654 7.71030063600159e-4 0.0028528112353205883 0.001602276397023081 8881/29945/8697/996/51434/51433 6 Hepatitis_E_virus_genotype_1 R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 5/664 13/10654 7.829757008846814e-4 0.0028692432233697433 0.0016115053941194721 7311/7316/10193/7314/6233 5 Hepatitis_E_virus_genotype_1 R-HSA-179812 GRB2 events in EGFR signaling 5/664 13/10654 7.829757008846814e-4 0.0028692432233697433 0.0016115053941194721 1956/3265/1950/6654/2885 5 Hepatitis_E_virus_genotype_1 R-HSA-5210891 Uptake and function of anthrax toxins 5/664 13/10654 7.829757008846814e-4 0.0028692432233697433 0.0016115053941194721 84168/10015/5606/6416/5609 5 Hepatitis_E_virus_genotype_1 R-HSA-202733 Cell surface interactions at the vascular wall 19/664 137/10654 8.2271608832316e-4 0.003005271825817403 0.0016879056186851291 5295/914/3932/4067/3635/857/5290/338/5335/2335/2534/3265/8795/2147/6714/6520/6654/2885/8797 19 Hepatitis_E_virus_genotype_1 R-HSA-69242 S Phase 21/664 161/10654 0.001012372653211004 0.0036863220102635605 0.002070416253183407 5925/7311/5684/6502/5983/6117/8881/5682/7316/4174/1163/5707/1026/29945/8697/4609/7314/996/6233/51434/51433 21 Hepatitis_E_virus_genotype_1 R-HSA-1500931 Cell-Cell communication 18/664 129/10654 0.0010395322151409583 0.003765657953837242 0.002114975145916939 5295/8826/4868/2185/999/5290/81/2534/7408/5584/5747/64398/4690/6714/7827/8976/23607/2885 18 Hepatitis_E_virus_genotype_1 R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 6/664 20/10654 0.0010440097901658614 0.003765657953837242 0.002114975145916939 8881/29945/8697/996/51434/51433 6 Hepatitis_E_virus_genotype_1 R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 6/664 20/10654 0.0010440097901658614 0.003765657953837242 0.002114975145916939 8881/29945/8697/996/51434/51433 6 Hepatitis_E_virus_genotype_1 R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 11/664 60/10654 0.0010525593796084942 0.0037845943837333633 0.0021256107583580218 1147/7311/5684/5682/7316/5707/9020/5970/4791/7314/6233 11 Hepatitis_E_virus_genotype_1 R-HSA-69239 Synthesis of DNA 17/664 119/10654 0.0010879056236353232 0.0038994617197178616 0.0021901257949500587 7311/5684/6502/5983/6117/8881/5682/7316/4174/5707/29945/8697/7314/996/6233/51434/51433 17 Hepatitis_E_virus_genotype_1 R-HSA-5696395 Formation of Incision Complex in GG-NER 9/664 43/10654 0.001116454977263169 0.003989326663304844 0.0022405982819644517 7311/7336/6117/54778/7316/7329/7314/6233/8554 9 Hepatitis_E_virus_genotype_1 R-HSA-180336 SHC1 events in EGFR signaling 5/664 14/10654 0.001155923726353567 0.00409211269792451 0.0022983278769603092 1956/3265/1950/6654/2885 5 Hepatitis_E_virus_genotype_1 R-HSA-3371568 Attenuation phase 5/664 14/10654 0.001155923726353567 0.00409211269792451 0.0022983278769603092 3303/3337/3320/2033/3312 5 Hepatitis_E_virus_genotype_1 R-HSA-9027284 Erythropoietin activates RAS 5/664 14/10654 0.001155923726353567 0.00409211269792451 0.0022983278769603092 7409/4067/3265/6654/2885 5 Hepatitis_E_virus_genotype_1 R-HSA-8878166 Transcriptional regulation by RUNX2 17/664 121/10654 0.0013130152637249226 0.00463393386920765 0.0026026407818612236 5925/7311/367/25/5684/6502/2908/5682/7316/5707/1026/6772/6714/5594/7314/6233/5595 17 Human_adenovirus_C_serotype_2 R-HSA-72649 Translation initiation complex formation 26/206 58/10654 7.240296025746026e-30 5.6280732102209284e-27 3.706030584963293e-27 8669/8664/3646/8662/26986/8663/6228/6203/51386/6188/27335/8665/6201/1981/8661/8666/1973/6187/1977/1974/1964/6205/8668/1975/1968/8667 26 Human_adenovirus_C_serotype_2 R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 26/206 59/10654 1.2733197308192146e-29 5.6280732102209284e-27 3.706030584963293e-27 8669/8664/3646/8662/26986/8663/6228/6203/51386/6188/27335/8665/6201/1981/8661/8666/1973/6187/1977/1974/1964/6205/8668/1975/1968/8667 26 Human_adenovirus_C_serotype_2 R-HSA-72702 Ribosomal scanning and start codon recognition 25/206 58/10654 3.2880262745558722e-28 9.688717422357971e-26 6.379924666068062e-26 8669/8664/3646/8662/8663/6228/6203/51386/6188/27335/8665/6201/1981/8661/8666/1973/6187/1977/1974/1964/6205/8668/1975/1968/8667 25 Human_adenovirus_C_serotype_2 R-HSA-72613 Eukaryotic Translation Initiation 27/206 119/10654 8.512529714676945e-22 1.4205970197173084e-19 9.354490972894398e-20 8669/8664/3646/8662/26986/8663/6228/6203/51386/6188/27335/8665/6201/1981/8661/8666/1973/6187/9669/1977/1974/1964/6205/8668/1975/1968/8667 27 Human_adenovirus_C_serotype_2 R-HSA-72737 Cap-dependent Translation Initiation 27/206 119/10654 8.512529714676945e-22 1.4205970197173084e-19 9.354490972894398e-20 8669/8664/3646/8662/26986/8663/6228/6203/51386/6188/27335/8665/6201/1981/8661/8666/1973/6187/9669/1977/1974/1964/6205/8668/1975/1968/8667 27 Human_adenovirus_C_serotype_2 R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 20/206 51/10654 9.642061219800735e-22 1.4205970197173084e-19 9.354490972894398e-20 8669/8664/3646/8662/8663/6228/6203/51386/6188/27335/8665/6201/8661/8666/6187/1964/6205/8668/1968/8667 20 Human_adenovirus_C_serotype_2 R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 26/206 111/10654 2.1145317249795427e-21 2.670351492688451e-19 1.7584000660356199e-19 8669/8664/3646/8662/26986/8663/6228/6203/51386/6188/27335/8665/6201/1981/8661/8666/1973/6187/1977/1974/1964/6205/8668/1975/1968/8667 26 Human_adenovirus_C_serotype_2 R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 26/206 112/10654 2.7086409404706874e-21 2.9930482392201096e-19 1.9708926843161715e-19 8669/8664/3646/8662/8663/6228/6203/51386/6188/27335/8665/6201/1981/8661/8666/1973/6187/9669/1977/1974/1964/6205/8668/1975/1968/8667 26 Human_adenovirus_C_serotype_2 R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 31/206 244/10654 3.9160101894260894e-17 3.846392230502959e-15 2.5328112687165237e-15 10450/1665/988/22827/3178/10236/23524/8683/9775/10189/6430/6627/7175/5093/24148/10594/4686/6625/2733/11338/9343/11193/1660/4116/55746/56339/4904/2521/1977/4927/1994 31 Human_adenovirus_C_serotype_2 R-HSA-72163 mRNA Splicing - Major Pathway 25/206 183/10654 9.951982735825563e-15 8.797552738469799e-13 5.793101529380565e-13 10450/1665/988/22827/3178/10236/23524/8683/9775/10189/6430/6627/5093/24148/10594/4686/6625/11338/9343/11193/1660/4116/4904/2521/1994 25 Human_adenovirus_C_serotype_2 R-HSA-72172 mRNA Splicing 25/206 191/10654 2.7366898978379848e-14 2.1993035178988897e-12 1.4482196301477566e-12 10450/1665/988/22827/3178/10236/23524/8683/9775/10189/6430/6627/5093/24148/10594/4686/6625/11338/9343/11193/1660/4116/4904/2521/1994 25 Human_adenovirus_C_serotype_2 R-HSA-72689 Formation of a pool of free 40S subunits 19/206 101/10654 4.865217312007335e-14 3.584043419845404e-12 2.3600571697719793e-12 8669/8664/3646/8662/8663/6228/6203/51386/6188/27335/8665/6201/8661/8666/6187/1964/6205/8668/8667 19 Human_adenovirus_C_serotype_2 R-HSA-72766 Translation 27/206 291/10654 1.0596361523268955e-11 7.205525835822889e-10 4.744767548475897e-10 8669/8664/3646/8662/26986/8663/6228/6203/51386/6188/27335/8665/6201/1981/8661/8666/1973/6187/9669/1977/1974/1964/6205/8668/1975/1968/8667 27 Human_adenovirus_C_serotype_2 R-HSA-8943724 Regulation of PTEN gene transcription 13/206 61/10654 1.0499872435958443e-10 6.629919452419475e-9 4.365736433898511e-9 10014/8726/23512/6615/2146/3066/5978/7157/53615/1107/6045/1108/2122 13 Human_adenovirus_C_serotype_2 R-HSA-1257604 PIP3 activates AKT signaling 23/206 264/10654 1.3970245409144593e-9 8.109842861844862e-8 5.340251372469884e-8 10014/23198/27161/2931/6199/5296/8726/23512/6615/2146/3066/5978/7157/53615/1107/1457/4734/6045/7189/2099/1108/5879/2122 23 Human_adenovirus_C_serotype_2 R-HSA-6807070 PTEN Regulation 17/206 140/10654 1.4678448618723733e-9 8.109842861844862e-8 5.340251372469884e-8 10014/23198/27161/8726/23512/6615/2146/3066/5978/7157/53615/1107/1457/4734/6045/1108/2122 17 Human_adenovirus_C_serotype_2 R-HSA-9006925 Intracellular signaling by second messengers 24/206 305/10654 4.631107567768182e-9 2.408175935239455e-7 1.5857600526165972e-7 10014/23198/27161/2931/6199/5296/8726/23512/801/6615/2146/3066/5978/7157/53615/1107/1457/4734/6045/7189/2099/1108/5879/2122 24 Human_adenovirus_C_serotype_2 R-HSA-1169408 ISG15 antiviral mechanism 12/206 72/10654 1.1007014119303093e-8 5.40566693414663e-7 3.55957825027755e-7 5300/9775/7175/1981/1973/55746/3661/4734/1977/1974/4927/23586 12 Human_adenovirus_C_serotype_2 R-HSA-5663205 Infectious disease 26/206 383/10654 2.211356740843472e-8 1.028862820476647e-6 6.774959987182493e-7 23198/7514/1025/1173/6228/6203/8065/999/6188/7040/7175/6201/4686/5604/1499/9978/2547/801/6187/920/55746/4927/8148/6205/5879/4869 26 Human_adenovirus_C_serotype_2 R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 12/206 80/10654 3.7691501638903136e-8 1.6659643724395188e-6 1.0970210740164969e-6 5300/9775/7175/1981/1973/55746/3661/4734/1977/1974/4927/23586 12 Human_adenovirus_C_serotype_2 R-HSA-72202 Transport of Mature Transcript to Cytoplasm 12/206 84/10654 6.605871569306068e-8 2.6852708744159524e-6 1.7682243314503716e-6 8683/9775/10189/6430/7175/4686/2733/11338/4116/55746/1977/4927 12 Human_adenovirus_C_serotype_2 R-HSA-5663202 Diseases of signal transduction 25/206 377/10654 6.682800818682235e-8 2.6852708744159524e-6 1.7682243314503716e-6 10014/8454/23198/4000/409/27044/8826/10013/2931/6199/4088/5296/7040/2335/3845/4686/5604/1499/9978/801/3066/11140/5245/2099/5879 25 Human_adenovirus_C_serotype_2 R-HSA-8951664 Neddylation 19/206 234/10654 1.2586906268977e-7 4.723756994419193e-6 3.1105472944913244e-6 8454/23198/54165/83987/26270/7347/23291/8065/55832/8452/23363/8450/9978/10987/7428/8453/4738/9820/10980 19 Human_adenovirus_C_serotype_2 R-HSA-918233 TRAF3-dependent IRF activation pathway 6/206 14/10654 1.2824679622857539e-7 4.723756994419193e-6 3.1105472944913244e-6 7187/9641/3661/29110/57506/23586 6 Human_adenovirus_C_serotype_2 R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 11/206 75/10654 1.7948063765346294e-7 6.346435347426449e-6 4.1790649525206325e-6 8683/9775/10189/6430/7175/4686/2733/11338/4116/55746/4927 11 Human_adenovirus_C_serotype_2 R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 8/206 34/10654 2.0105713740698312e-7 6.835942671837426e-6 4.5014006876948045e-6 7187/5300/9641/1540/3661/29110/57506/23586 8 Human_adenovirus_C_serotype_2 R-HSA-429947 Deadenylation of mRNA 7/206 25/10654 3.264125280166492e-7 1.0686987954322884e-5 7.03727594515427e-6 26986/9775/1981/1973/1977/1974/1975 7 Human_adenovirus_C_serotype_2 R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 16/206 182/10654 4.448651657124927e-7 1.40450288032087e-5 9.248512655601823e-6 6613/9641/6117/7175/23512/5885/7428/3066/7157/1107/55746/6045/4791/2099/4927/4869 16 Human_adenovirus_C_serotype_2 R-HSA-2990846 SUMOylation 16/206 188/10654 6.902167297974497e-7 2.1039709970377434e-5 1.385444107361124e-5 6613/9641/6117/7175/23512/5885/7428/3066/7157/1107/55746/6045/4791/2099/4927/4869 16 Human_adenovirus_C_serotype_2 R-HSA-170834 Signaling by TGF-beta Receptor Complex 10/206 73/10654 1.2628935303061254e-6 3.721326269302049e-5 2.450456569330833e-5 7514/1025/5590/4088/7040/8239/5501/6667/4738/5500 10 Human_adenovirus_C_serotype_2 R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 10/206 78/10654 2.351502903528642e-6 6.705576021675225e-5 4.415555537016432e-5 7187/5300/9641/1540/3661/4791/29110/7189/57506/23586 10 Human_adenovirus_C_serotype_2 R-HSA-9010553 Regulation of expression of SLITs and ROBOs 14/206 171/10654 5.524107671377532e-6 1.5260347442180432e-4 1.0048787967999262e-4 23198/26986/6228/6203/6188/9775/6201/1981/4686/9978/6187/4116/8453/6205 14 Human_adenovirus_C_serotype_2 R-HSA-5689896 Ovarian tumor domain proteases 7/206 38/10654 6.922990639589908e-6 1.803453062947583e-4 1.1875560178733192e-4 7187/79155/7157/7189/2099/57506/23586 7 Human_adenovirus_C_serotype_2 R-HSA-913531 Interferon Signaling 15/206 199/10654 7.020431161216924e-6 1.803453062947583e-4 1.1875560178733192e-4 3383/5300/9775/7175/1981/1973/7412/55746/3661/4734/1977/1974/9830/4927/23586 15 Human_adenovirus_C_serotype_2 R-HSA-162909 Host Interactions of HIV factors 12/206 129/10654 7.140368461896539e-6 1.803453062947583e-4 1.1875560178733192e-4 23198/7514/1025/1173/8065/7175/9978/920/55746/4927/5879/4869 12 Human_adenovirus_C_serotype_2 R-HSA-6802957 Oncogenic MAPK signaling 9/206 71/10654 8.37117945713719e-6 2.0555896222525767e-4 1.353585450233002e-4 4000/409/27044/8826/2335/3845/5604/801/5245 9 Human_adenovirus_C_serotype_2 R-HSA-449147 Signaling by Interleukins 24/206 461/10654 9.221636545543335e-6 2.2032234341244075e-4 1.4508008562405305e-4 8454/23198/7124/3575/3383/9987/23291/4088/3636/5296/7040/4843/2335/6627/5604/9978/79155/7412/920/7157/4791/29110/7189/1398 24 Human_adenovirus_C_serotype_2 R-HSA-429914 Deadenylation-dependent mRNA decay 8/206 56/10654 1.092113862539587e-5 2.540601722328934e-4 1.6729611246105034e-4 26986/9775/1981/1973/1977/1974/80349/1975 8 Human_adenovirus_C_serotype_2 R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 10/206 94/10654 1.291568303183366e-5 2.862612695906429e-4 1.8850021681784414e-4 8454/7187/23291/9641/5604/79155/3661/4791/29110/7189 10 Human_adenovirus_C_serotype_2 R-HSA-927802 Nonsense-Mediated Decay (NMD) 11/206 115/10654 1.3276823589611263e-5 2.862612695906429e-4 1.8850021681784414e-4 26986/6228/6203/6188/9775/6201/1981/4686/6187/4116/6205 11 Human_adenovirus_C_serotype_2 R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 11/206 115/10654 1.3276823589611263e-5 2.862612695906429e-4 1.8850021681784414e-4 26986/6228/6203/6188/9775/6201/1981/4686/6187/4116/6205 11 Human_adenovirus_C_serotype_2 R-HSA-933541 TRAF6 mediated IRF7 activation 6/206 29/10654 1.591837001824856e-5 3.3504378800313636e-4 2.206230230599362e-4 9641/3661/29110/7189/57506/23586 6 Human_adenovirus_C_serotype_2 R-HSA-6804758 Regulation of TP53 Activity through Acetylation 6/206 30/10654 1.9579617853150447e-5 4.0202442391195747e-4 2.6472910981580435e-4 5300/3066/7157/53615/1107/1108 6 Human_adenovirus_C_serotype_2 R-HSA-166166 MyD88-independent TLR4 cascade 10/206 99/10654 2.0465044203662992e-5 4.0202442391195747e-4 2.6472910981580435e-4 8454/7187/23291/9641/5604/79155/3661/4791/29110/7189 10 Human_adenovirus_C_serotype_2 R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 10/206 99/10654 2.0465044203662992e-5 4.0202442391195747e-4 2.6472910981580435e-4 8454/7187/23291/9641/5604/79155/3661/4791/29110/7189 10 Human_adenovirus_C_serotype_2 R-HSA-376176 Signaling by ROBO receptors 15/206 218/10654 2.0948953691094883e-5 4.025842404984321e-4 2.650977435051595e-4 23198/26986/6228/6203/6188/9775/6201/1981/4686/9978/6187/4116/8453/6205/5879 15 Human_adenovirus_C_serotype_2 R-HSA-73894 DNA Repair 19/206 334/10654 2.495120094138577e-5 4.692949283443621e-4 3.090260721295931e-4 10450/1017/6119/7014/6118/25913/23030/6613/6117/8450/10973/9978/322/328/2547/10987/7157/10980/7528 19 Human_adenovirus_C_serotype_2 R-HSA-9006936 Signaling by TGF-beta family members 10/206 102/10654 2.66082916384997e-5 4.900360376757028e-4 3.2268388763356e-4 7514/1025/5590/4088/7040/8239/5501/6667/4738/5500 10 Human_adenovirus_C_serotype_2 R-HSA-2173789 TGF-beta receptor signaling activates SMADs 6/206 32/10654 2.893342548644236e-5 4.965777662687913e-4 3.2699155125820624e-4 7514/4088/7040/5501/4738/5500 6 Human_adenovirus_C_serotype_2 R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 7/206 47/10654 2.9772196393943364e-5 4.965777662687913e-4 3.2699155125820624e-4 409/8826/2335/3845/5604/801/5245 7 Human_adenovirus_C_serotype_2 R-HSA-6802949 Signaling by RAS mutants 7/206 47/10654 2.9772196393943364e-5 4.965777662687913e-4 3.2699155125820624e-4 409/8826/2335/3845/5604/801/5245 7 Human_adenovirus_C_serotype_2 R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 7/206 47/10654 2.9772196393943364e-5 4.965777662687913e-4 3.2699155125820624e-4 409/8826/2335/3845/5604/801/5245 7 Human_adenovirus_C_serotype_2 R-HSA-9649948 Signaling downstream of RAS mutants 7/206 47/10654 2.9772196393943364e-5 4.965777662687913e-4 3.2699155125820624e-4 409/8826/2335/3845/5604/801/5245 7 Human_adenovirus_C_serotype_2 R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 9/206 84/10654 3.331497090373115e-5 5.453784125721915e-4 3.591262945372968e-4 6119/6118/6613/6117/8450/9978/10987/10980/7528 9 Human_adenovirus_C_serotype_2 R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 11/206 129/10654 3.921444765088016e-5 6.302831222432375e-4 4.150352067164924e-4 8454/7187/23291/9641/5604/79155/3661/695/4791/29110/7189 11 Human_adenovirus_C_serotype_2 R-HSA-159227 Transport of the SLBP independent Mature mRNA 6/206 34/10654 4.157923207541619e-5 6.483122477152778e-4 4.269072076524752e-4 10189/7175/4686/55746/1977/4927 6 Human_adenovirus_C_serotype_2 R-HSA-6802952 Signaling by BRAF and RAF fusions 8/206 67/10654 4.180293904951452e-5 6.483122477152778e-4 4.269072076524752e-4 4000/409/27044/8826/2335/3845/5604/801 8 Human_adenovirus_C_serotype_2 R-HSA-162906 HIV Infection 15/206 233/10654 4.550626571541382e-5 6.935782567659624e-4 4.5671442723455247e-4 23198/7514/1025/1173/8065/7175/4686/9978/2547/920/55746/4927/8148/5879/4869 15 Human_adenovirus_C_serotype_2 R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 6/206 35/10654 4.938014840147639e-5 7.398652743543241e-4 4.8719397084775106e-4 10189/7175/4686/55746/1977/4927 6 Human_adenovirus_C_serotype_2 R-HSA-5696398 Nucleotide Excision Repair 10/206 111/10654 5.537005339251013e-5 8.157854533163159e-4 5.371866583518966e-4 10450/6119/6118/6613/6117/8450/9978/10987/10980/7528 10 Human_adenovirus_C_serotype_2 R-HSA-3371511 HSF1 activation 4/206 12/10654 5.9501779524574005e-5 8.483802112858616e-4 5.586499843308902e-4 6119/6118/10013/6117 4 Human_adenovirus_C_serotype_2 R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 4/206 12/10654 5.9501779524574005e-5 8.483802112858616e-4 5.586499843308902e-4 7187/9641/3661/29110 4 Human_adenovirus_C_serotype_2 R-HSA-5633007 Regulation of TP53 Activity 12/206 160/10654 6.224973609251332e-5 8.650974506613209e-4 5.696581212380453e-4 1017/6119/6118/5300/6117/3066/7157/53615/1107/1457/1108/8148 12 Human_adenovirus_C_serotype_2 R-HSA-5688426 Deubiquitination 17/206 297/10654 6.263148964063861e-5 8.650974506613209e-4 5.696581212380453e-4 23198/409/9097/7187/7347/4088/7040/8239/1540/79155/7157/4738/7189/2099/57506/7528/23586 17 Human_adenovirus_C_serotype_2 R-HSA-4551638 SUMOylation of chromatin organization proteins 8/206 71/10654 6.382739460562724e-5 8.680525666365304e-4 5.716040359014067e-4 6613/7175/23512/3066/1107/55746/6045/4927 8 Human_adenovirus_C_serotype_2 R-HSA-8953897 Cellular responses to external stimuli 23/206 493/10654 7.963640381027978e-5 0.0010666451661861716 7.023752999535043e-4 23198/1017/6119/7014/6118/10013/25913/8726/6117/4520/7175/23512/9978/8655/7428/2146/7157/8453/55746/6045/6667/4927/9296 23 Human_adenovirus_C_serotype_2 R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 9/206 95/10654 8.853622128600495e-5 0.0011681495465198264 7.692149312044106e-4 26986/6228/6203/6188/6201/1981/4686/6187/6205 9 Human_adenovirus_C_serotype_2 R-HSA-72187 mRNA 3'-end processing 7/206 58/10654 1.1892053026432035e-4 0.0015459668934361644 0.001018003920064538 8683/9775/10189/6430/4686/11338/4116 7 Human_adenovirus_C_serotype_2 R-HSA-2173788 Downregulation of TGF-beta receptor signaling 5/206 26/10654 1.2162066588952953e-4 0.001558154618062958 0.0010260294162762753 7514/4088/7040/5501/5500 5 Human_adenovirus_C_serotype_2 R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 6/206 41/10654 1.242035965021652e-4 0.0015685139901130578 0.0010328509603864265 10189/7175/4686/55746/1977/4927 6 Human_adenovirus_C_serotype_2 R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 8/206 79/10654 1.37155563157261e-4 0.001707683349732658 0.0011244926082426292 10450/6119/6118/6117/8450/9978/10987/10980 8 Human_adenovirus_C_serotype_2 R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 6/206 42/10654 1.4259411776318027e-4 0.0017414554663799154 0.0011467312132747002 10189/7175/4686/55746/1977/4927 6 Human_adenovirus_C_serotype_2 R-HSA-2262752 Cellular responses to stress 22/206 479/10654 1.4380797403363554e-4 0.0017414554663799154 0.0011467312132747002 23198/1017/6119/7014/6118/10013/25913/8726/6117/7175/23512/9978/8655/7428/2146/7157/8453/55746/6045/6667/4927/9296 22 Human_adenovirus_C_serotype_2 R-HSA-5696395 Formation of Incision Complex in GG-NER 6/206 43/10654 1.6307640836109294e-4 0.0019481019593406237 0.0012828058865388963 6119/6118/6613/6117/8450/9978 6 Human_adenovirus_C_serotype_2 R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 7/206 63/10654 2.0168915441350264e-4 0.002333126855646613 0.001536340975437696 170506/1499/2547/1660/3661/4791/29110 7 Human_adenovirus_C_serotype_2 R-HSA-168254 Influenza Infection 11/206 155/10654 2.0580506611090832e-4 0.002333126855646613 0.001536340975437696 7514/6228/6203/6188/7040/7175/6201/6187/55746/4927/6205 11 Human_adenovirus_C_serotype_2 R-HSA-168898 Toll-like Receptor Cascades 11/206 155/10654 2.0580506611090832e-4 0.002333126855646613 0.001536340975437696 8454/7187/23291/9641/5604/79155/3661/695/4791/29110/7189 11 Human_adenovirus_C_serotype_2 R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 4/206 16/10654 2.0586413432175995e-4 0.002333126855646613 0.001536340975437696 8454/23291/5604/79155 4 Human_adenovirus_C_serotype_2 R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 5/206 30/10654 2.474294532622084e-4 0.0027687042618201544 0.0018231643924583778 6119/6118/6117/8450/9978 5 Human_adenovirus_C_serotype_2 R-HSA-3247509 Chromatin modifying enzymes 15/206 274/10654 2.76811986072019e-4 0.0030210098233045034 0.001989305111082866 23030/8726/7403/23512/10284/6187/2146/3066/5978/53615/1107/6871/4791/1108/2122 15 Human_adenovirus_C_serotype_2 R-HSA-4839726 Chromatin organization 15/206 274/10654 2.76811986072019e-4 0.0030210098233045034 0.001989305111082866 23030/8726/7403/23512/10284/6187/2146/3066/5978/53615/1107/6871/4791/1108/2122 15 Human_adenovirus_C_serotype_2 R-HSA-73856 RNA Polymerase II Transcription Termination 7/206 67/10654 2.9702012966869126e-4 0.003202021885696623 0.0021084997651705556 8683/9775/10189/6430/4686/11338/4116 7 Human_adenovirus_C_serotype_2 R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 4/206 18/10654 3.357736663301489e-4 0.0035658955240172865 0.0023481069597303637 7187/9641/3661/29110 4 Human_adenovirus_C_serotype_2 R-HSA-5626467 RHO GTPases activate IQGAPs 5/206 32/10654 3.388407511509639e-4 0.0035658955240172865 0.0023481069597303637 8826/999/1499/801/5879 5 Human_adenovirus_C_serotype_2 R-HSA-446652 Interleukin-1 family signaling 10/206 140/10654 3.7945259368908033e-4 0.003946306974366436 0.0025986041400626807 8454/23198/23291/4088/5604/9978/79155/4791/29110/7189 10 Human_adenovirus_C_serotype_2 R-HSA-8939211 ESR-mediated signaling 13/206 223/10654 3.894210138366188e-4 0.003968138560235576 0.002612980023589276 7514/1025/27161/23030/5590/5296/3845/5885/801/861/6667/2099/7528 13 Human_adenovirus_C_serotype_2 R-HSA-68962 Activation of the pre-replicative complex 5/206 33/10654 3.9313413551411193e-4 0.003968138560235576 0.002612980023589276 1017/6119/6118/6117/4171 5 Human_adenovirus_C_serotype_2 R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 8/206 92/10654 3.9501831821349626e-4 0.003968138560235576 0.002612980023589276 1017/6119/6118/5300/6117/7157/1457/8148 8 Human_adenovirus_C_serotype_2 R-HSA-2980766 Nuclear Envelope Breakdown 6/206 52/10654 4.7137151683310637e-4 0.004664186518707219 0.003071320724988202 4000/7443/7175/55746/7112/4927 6 Human_adenovirus_C_serotype_2 R-HSA-168255 Influenza Life Cycle 10/206 144/10654 4.7486061842041824e-4 0.004664186518707219 0.003071320724988202 7514/6228/6203/6188/7175/6201/6187/55746/4927/6205 10 Human_coronavirus_229E R-HSA-9006936 Signaling by TGF-beta family members 91/947 102/10654 2.643876289168618e-84 3.3207086191957846e-81 1.6447693546301616e-81 269/4089/4093/50855/22938/7514/57154/7048/1025/4086/1030/11171/60436/658/7311/23327/56288/25937/51592/9110/867/3726/23645/8812/7050/5590/7046/8928/92/387/4088/23370/650/7040/64750/57530/50848/659/130399/7323/10589/1874/904/8239/54778/7316/142/892/1875/9611/905/7027/23439/9765/5501/94/91/93/2658/7321/5494/51377/3065/25805/3624/2280/6497/6498/9612/9958/10273/56937/1024/4087/4091/5499/6667/5933/4092/5500/5045/268/4090/4609/7314/657/6233/4221/5054/3625/9372 91 Human_coronavirus_229E R-HSA-170834 Signaling by TGF-beta Receptor Complex 70/947 73/10654 1.1596621761185856e-70 7.282678466024717e-68 3.607159716242548e-68 4089/50855/22938/7514/57154/7048/1025/1030/11171/60436/7311/23327/56288/25937/51592/9110/867/3726/23645/8812/7050/5590/7046/387/4088/23370/7040/64750/57530/50848/7323/1874/904/8239/54778/7316/142/892/1875/9611/905/7027/23439/5501/7321/5494/51377/3065/25805/2280/6497/6498/9612/9958/10273/56937/1024/4087/5499/6667/5933/4092/5500/5045/4609/7314/6233/4221/5054/9372 70 Human_coronavirus_229E R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 43/947 44/10654 1.05222242543986e-44 4.405304554508214e-42 2.1819770295963412e-42 4089/22938/1025/1030/60436/7311/23327/25937/51592/3726/8812/7050/4088/64750/7323/1874/904/8239/54778/7316/142/892/1875/9611/905/7027/23439/7321/5494/3065/6497/6498/9612/1024/4087/6667/5933/4092/4609/7314/6233/4221/5054 43 Human_coronavirus_229E R-HSA-114608 Platelet degranulation 70/947 129/10654 4.669394870846459e-40 1.466189989445788e-37 7.262137812290151e-38 5004/88/2266/1675/3082/1191/10490/2157/3273/7277/7076/3479/5155/226/83706/2243/197/7044/351/7450/374354/2244/51368/7114/29789/5005/5196/81/7040/5265/3309/3827/10916/7018/54863/2335/1/2153/3690/2162/6678/7042/213/5340/1950/5660/51097/87/5345/7057/2621/7424/2316/7423/3481/78991/54676/7043/7422/5768/5627/2/710/22915/3671/5054/5473/6647/5552/139322 70 Human_coronavirus_229E R-HSA-76002 Platelet activation, signaling and aggregation 100/947 262/10654 1.6742173018040352e-39 4.2056338621317365e-37 2.0830787902445998e-37 5295/5004/88/2266/7409/1675/3082/1191/10490/2157/3273/5170/1432/7277/5777/3932/7076/3479/3708/5155/226/83706/2243/5590/197/4067/1277/7044/351/7450/387/3710/6464/5290/374354/2244/51368/7114/29789/5005/5196/81/7040/5265/3309/3827/10916/7018/54863/2335/1/2534/2153/3690/2162/6678/7042/391/213/5340/1950/5660/51097/1445/1606/87/5345/5781/7057/2621/7424/5336/1278/2316/7423/6850/207/3481/78991/54676/3709/7043/2147/7422/5768/5627/2/5594/710/22915/3671/6654/2885/5595/5054/5473/6647/5552/139322/7410 100 Human_coronavirus_229E R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 70/947 134/10654 1.332523739494856e-38 2.7894163613425652e-36 1.381616719370982e-36 5004/88/2266/1675/3082/1191/10490/2157/3273/7277/7076/3479/5155/226/83706/2243/197/7044/351/7450/374354/2244/51368/7114/29789/5005/5196/81/7040/5265/3309/3827/10916/7018/54863/2335/1/2153/3690/2162/6678/7042/213/5340/1950/5660/51097/87/5345/7057/2621/7424/2316/7423/3481/78991/54676/7043/7422/5768/5627/2/710/22915/3671/5054/5473/6647/5552/139322 70 Human_coronavirus_229E R-HSA-449147 Signaling by Interleukins 128/947 461/10654 9.185933421691238e-34 1.6482189110920278e-31 8.163739326645898e-32 5295/8454/7409/6500/3082/7124/1147/5898/2353/5778/2308/604/7311/3091/834/1154/1052/29760/10148/1432/3725/5777/4208/8945/23118/867/25930/3932/79923/4318/7076/3726/4312/5293/5518/5705/6950/4067/1386/5601/351/11009/9252/6382/6464/4088/6657/2247/5290/6778/4615/3313/7040/6935/3667/5602/4790/3662/2335/6885/5599/2534/5528/84867/5784/7431/6597/2162/5606/2309/3688/5682/4313/1436/7316/595/57162/6175/9978/3312/26469/5657/3929/79155/5771/5782/5783/6352/3458/10454/7297/27250/5781/5702/5608/27178/6774/3569/7157/5970/4205/1278/6850/1026/5780/207/3911/3586/7422/5714/3553/6772/2625/5594/8878/6654/4609/7314/6233/2885/3635/54472/5595/5775/6647/5717/257397/821 128 Human_coronavirus_229E R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 31/947 32/10654 4.837484349000693e-32 7.594850427931088e-30 3.761780592446592e-30 4089/22938/1025/1030/60436/7311/25937/3726/8812/7050/4088/1874/904/54778/7316/892/1875/905/7027/23439/3065/1024/4087/6667/5933/4092/4609/7314/6233/4221/5054 31 Human_coronavirus_229E R-HSA-5663202 Diseases of signal transduction 111/947 377/10654 9.356006386306461e-32 1.3056826690223239e-29 6.467134238955694e-30 2475/4089/5295/10014/7249/2266/8454/7409/6500/22938/3082/930/7048/1147/2308/8850/7311/818/5170/2932/10256/867/10013/3932/1387/815/2931/5293/5518/5155/5705/2243/7046/7450/6464/1956/6469/4088/8841/60/2247/5290/118788/2244/7040/3164/3667/22943/5335/26508/71/2335/3845/1487/2534/2033/3690/5528/2309/5682/4686/7316/391/1499/5728/3265/9978/2648/10018/1950/892/9611/8312/5529/1445/5781/5702/3065/3066/10956/6774/4851/5430/2280/23462/9759/9612/1026/207/1024/4087/7750/11140/5714/6772/2099/6934/5594/6654/4303/4609/7314/6233/2885/613/5595/1488/4041/5717/1027/9372 111 Human_coronavirus_229E R-HSA-2173789 TGF-beta receptor signaling activates SMADs 30/947 32/10654 7.961415822269936e-30 9.99953827277104e-28 4.952838685222665e-28 4089/7514/57154/7048/11171/7311/23327/9110/867/23645/7046/4088/7040/64750/7316/5501/51377/25805/2280/9958/10273/56937/4087/5499/4092/5500/5045/7314/6233/9372 30 Human_coronavirus_229E R-HSA-2173788 Downregulation of TGF-beta receptor signaling 26/947 26/10654 3.408999925037861e-28 3.8924580962250483e-26 1.9279607231553835e-26 7514/57154/7048/11171/7311/23327/9110/23645/7046/4088/7040/64750/7316/5501/51377/25805/9958/10273/56937/4087/5499/4092/5500/7314/6233/9372 26 Human_coronavirus_229E R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 23/947 23/10654 5.207414980383906e-25 5.450427679468488e-23 2.6996335556200777e-23 4089/60436/7311/23327/51592/7050/4088/64750/7323/8239/54778/7316/142/9611/7321/5494/3065/6497/6498/9612/4087/7314/6233 23 Human_coronavirus_229E R-HSA-9006925 Intracellular signaling by second messengers 86/947 305/10654 2.842423312035708e-23 2.7462182153206533e-21 1.3602203865693148e-21 2475/5295/10014/7249/7409/1912/3082/930/57504/5931/1147/2308/7311/818/1460/5170/5928/3725/2932/6591/3932/815/3643/3838/2931/3708/5293/5518/5155/57761/5705/1386/57459/3710/1956/8841/2247/5290/118788/4615/3164/331/5573/3667/5335/2534/23512/5528/2309/5682/7316/391/5728/5468/1950/5529/7874/6615/5781/3630/5702/2146/3065/3066/7157/23028/1026/10273/207/4734/3709/5714/5371/2099/5594/57167/4303/7314/10542/6233/2122/2885/5595/11060/5717/1027 86 Human_coronavirus_229E R-HSA-1257604 PIP3 activates AKT signaling 78/947 264/10654 1.4162532949268473e-22 1.2705815274486571e-20 6.293275919562156e-21 2475/5295/10014/7249/7409/1912/3082/930/57504/5931/1147/2308/7311/1460/5170/5928/3725/2932/6591/3932/3643/2931/5293/5518/5155/57761/5705/1386/57459/1956/8841/2247/5290/118788/4615/3164/331/3667/2534/23512/5528/2309/5682/7316/391/5728/5468/1950/5529/7874/6615/5781/3630/5702/2146/3065/3066/7157/23028/1026/10273/207/4734/5714/5371/2099/5594/57167/4303/7314/10542/6233/2122/2885/5595/11060/5717/1027 78 Human_coronavirus_229E R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 107/947 473/10654 1.765836828098014e-20 1.4785940373940704e-18 7.323575897585447e-19 2475/5295/7409/3315/1281/3082/6093/3685/5898/7311/26999/5170/1432/5777/4208/23118/51741/867/3932/4318/3643/3479/3708/5518/5155/57761/5921/5590/4067/1277/9252/387/3710/8065/6464/1956/1280/60/857/2247/5290/529/6778/29924/160/3912/55824/3667/9146/5335/71/2335/3845/2534/3690/5528/3688/4686/6678/7316/1499/1500/3265/5340/26469/1950/9611/4690/5771/1445/5782/9047/5603/5781/3630/7057/6774/7424/5430/11059/4205/83737/1278/7423/10048/10273/207/3481/4734/3911/3915/3709/11140/10413/7422/2060/6772/5045/2099/5594/6654/7314/30011/6233/2885/5595/7410 107 Human_coronavirus_229E R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 24/947 32/10654 2.3731920816954196e-19 1.8629557841309043e-17 9.227345528171006e-18 5295/7409/930/29760/5777/3708/5293/4067/3710/118788/2534/27071/4690/973/933/5336/640/6850/695/3709/974/6654/30011/2885 24 Human_coronavirus_229E R-HSA-201451 Signaling by BMP 22/947 28/10654 1.339000814598115e-18 9.892853077266073e-17 4.8999967890246816e-17 269/4089/4093/57154/4086/658/92/650/64750/659/7323/9765/94/93/2658/7321/6497/4091/4092/268/4090/657 22 Human_coronavirus_229E R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 28/947 47/10654 3.403096692721644e-18 2.3746052478102135e-16 1.1761579797652e-16 10014/8454/6500/22938/8850/7311/3091/10013/1387/8841/26508/2033/7316/9978/2648/892/9611/3065/3066/4851/7088/23462/9759/9612/1024/4609/7314/6233 28 Human_coronavirus_229E R-HSA-8878159 Transcriptional regulation by RUNX3 40/947 96/10654 5.448607368257682e-18 3.6018162392271835e-16 1.7840038529863102e-16 4089/22938/463/57154/8850/7311/25937/51176/1387/5705/4088/7040/64750/3845/2033/2309/5682/7316/595/1499/2648/10018/1029/865/864/5702/4851/7157/9759/861/1026/83439/10413/5714/6934/4609/7314/6233/5717/6932 40 Human_coronavirus_229E R-HSA-983705 Signaling by the B Cell Receptor (BCR) 43/947 112/10654 1.2266638223852638e-17 7.431571585268158e-16 3.680907481472914e-16 5295/8454/7409/6500/930/1147/7311/29760/5777/8945/3708/5293/5705/4067/3710/118788/4790/3845/6885/2534/27071/5682/7316/3265/4690/973/5702/933/2280/5970/5336/640/6850/695/3709/5714/974/6654/7314/30011/6233/2885/5717 43 Human_coronavirus_229E R-HSA-202733 Cell surface interactions at the vascular wall 48/947 137/10654 1.2425398351164914e-17 7.431571585268158e-16 3.680907481472914e-16 5295/914/440533/3685/29802/5777/3932/4312/5676/4067/1277/6693/6383/6382/6464/3543/857/5290/5673/5196/7040/338/5335/50848/2335/3845/2534/3690/6385/3688/2817/5624/3265/5781/2621/5680/1278/5678/5675/5671/5672/5670/2147/5627/5669/6654/2885/3635 48 Human_coronavirus_229E R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 16/947 16/10654 1.3519350284685526e-17 7.691700052421456e-16 3.8097508640471675e-16 50855/57154/7048/7311/56288/5590/7046/387/23370/7040/57530/50848/7316/2280/7314/6233 16 Human_coronavirus_229E R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 26/947 42/10654 1.4085119522746297e-17 7.691700052421456e-16 3.8097508640471675e-16 7514/7311/6736/9070/51176/8945/9580/6657/331/6662/1487/7316/1499/3065/7088/207/8085/83439/6934/83595/57680/7314/6233/4221/6932/5929 26 Human_coronavirus_229E R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 42/947 108/10654 1.6903258643983858e-17 8.846038690351553e-16 4.3815025695589737e-16 5295/3082/7124/2353/2308/604/3091/1052/79923/4318/7076/3726/4312/6657/2247/6778/7040/6935/3662/2335/7431/2162/2309/3688/4313/595/3312/3929/7297/6774/3569/7157/1278/1026/207/3911/3586/7422/3553/6772/2625/4609 42 Human_coronavirus_229E R-HSA-168898 Toll-like Receptor Cascades 51/947 155/10654 2.541412066590415e-17 1.25344859705334e-15 6.20841536086594e-16 2266/8454/6500/1147/2353/3665/7311/1432/3725/4208/8945/23118/5518/2243/1386/5601/351/9252/7099/2244/4615/5602/338/4790/6885/5599/5528/7323/5606/7316/57162/3929/79155/10454/7321/5781/5608/5970/4205/5336/3661/695/6279/5594/7314/6233/5595/10010/5775/257397/4214 51 Human_coronavirus_229E R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 47/947 134/10654 2.594718433390672e-17 1.25344859705334e-15 6.20841536086594e-16 5295/8454/7409/6500/1147/2353/7311/5170/3725/8945/23118/3708/5705/4067/5601/3710/6464/5290/5602/5335/4790/3845/6885/5599/2534/5682/7316/3265/10454/7321/5702/5970/5336/6850/695/3709/5714/5594/6654/7314/6233/2885/5595/5717/257397/7410/4214 47 Human_coronavirus_229E R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 46/947 129/10654 2.702634518597236e-17 1.257225539021529e-15 6.227122808931643e-16 8454/6500/1147/2353/3665/7311/1432/3725/4208/8945/23118/5518/1386/5601/351/9252/7099/4615/5602/4790/6885/5599/5528/7323/5606/7316/57162/3929/79155/10454/7321/5781/5608/5970/4205/5336/3661/695/5594/7314/6233/5595/10010/5775/257397/4214 46 Human_coronavirus_229E R-HSA-8878166 Transcriptional regulation by RUNX2 44/947 121/10654 5.729835339926706e-17 2.5702404239099793e-15 1.2730574007130386e-15 4089/8454/6500/57154/4086/7311/25937/367/2932/860/10013/5705/1019/1277/6502/8841/650/2908/6662/5682/7316/595/9978/865/5702/11059/23462/9759/861/1026/10273/207/4091/10413/579/5714/6772/2099/5594/7314/6233/5595/5717/25925 44 Human_coronavirus_229E R-HSA-166166 MyD88-independent TLR4 cascade 39/947 99/10654 1.4432141578176958e-16 6.042256607396753e-15 2.99277041147459e-15 8454/6500/1147/2353/3665/7311/1432/3725/4208/8945/23118/5518/1386/5601/351/9252/7099/5602/4790/6885/5599/5528/7323/5606/7316/79155/10454/7321/5781/5608/5970/4205/3661/5594/7314/6233/5595/10010/257397 39 Human_coronavirus_229E R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 39/947 99/10654 1.4432141578176958e-16 6.042256607396753e-15 2.99277041147459e-15 8454/6500/1147/2353/3665/7311/1432/3725/4208/8945/23118/5518/1386/5601/351/9252/7099/5602/4790/6885/5599/5528/7323/5606/7316/79155/10454/7321/5781/5608/5970/4205/3661/5594/7314/6233/5595/10010/257397 39 Human_coronavirus_229E R-HSA-5663205 Infectious disease 86/947 383/10654 2.160681695958227e-16 8.75424583910817e-15 4.336036951821093e-15 6500/6158/7514/1025/7311/6204/23327/3303/5905/51652/9972/118429/8945/9636/4928/867/3932/6202/3837/3838/8812/57122/5705/9349/8065/6857/999/6188/6189/6232/160/8021/6206/6194/7040/6134/9146/6169/6191/2534/6135/5606/904/5682/4686/7316/1499/1938/6147/1500/6175/9978/293/6129/905/51497/2547/6124/5702/5608/5430/5901/292/6207/6208/6222/6157/6137/4836/9397/5714/6152/6136/2060/6193/5045/6122/6133/6210/6205/7314/30011/6233/2885/5717/821 86 Human_coronavirus_229E R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 37/947 93/10654 5.9783873468564445e-16 2.2754104568641498e-14 1.1270261314169566e-14 8454/6500/1147/2353/3665/7311/1432/3725/4208/8945/23118/5518/1386/5601/351/9252/7099/4615/5602/4790/6885/5599/5528/5606/7316/57162/79155/10454/5608/5970/4205/5594/7314/6233/5595/257397/4214 37 Human_coronavirus_229E R-HSA-975155 MyD88 dependent cascade initiated on endosome 37/947 93/10654 5.9783873468564445e-16 2.2754104568641498e-14 1.1270261314169566e-14 8454/6500/1147/2353/3665/7311/1432/3725/4208/8945/23118/5518/1386/5601/351/9252/7099/4615/5602/4790/6885/5599/5528/5606/7316/57162/79155/10454/5608/5970/4205/5594/7314/6233/5595/257397/4214 37 Human_coronavirus_229E R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 37/947 94/10654 9.035413475878965e-16 3.337788036971759e-14 1.6532289053388448e-14 8454/6500/1147/2353/3665/7311/1432/3725/4208/8945/23118/5518/1386/5601/351/9252/5602/4790/6885/5599/5528/7323/5606/7316/79155/10454/7321/5608/5970/4205/3661/5594/7314/6233/5595/10010/257397 37 Human_coronavirus_229E R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 35/947 85/10654 1.0370091335230284e-15 3.520225599202496e-14 1.7435914592094162e-14 8454/6500/1147/2353/7311/1432/3725/4208/8945/23118/5518/1386/5601/351/9252/4615/5602/4790/6885/5599/5528/5606/7316/57162/79155/10454/5608/5970/4205/5594/7314/6233/5595/257397/4214 35 Human_coronavirus_229E R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 35/947 85/10654 1.0370091335230284e-15 3.520225599202496e-14 1.7435914592094162e-14 8454/6500/1147/2353/7311/1432/3725/4208/8945/23118/5518/1386/5601/351/9252/4615/5602/4790/6885/5599/5528/5606/7316/57162/79155/10454/5608/5970/4205/5594/7314/6233/5595/257397/4214 35 Human_coronavirus_229E R-HSA-975871 MyD88 cascade initiated on plasma membrane 35/947 85/10654 1.0370091335230284e-15 3.520225599202496e-14 1.7435914592094162e-14 8454/6500/1147/2353/7311/1432/3725/4208/8945/23118/5518/1386/5601/351/9252/4615/5602/4790/6885/5599/5528/5606/7316/57162/79155/10454/5608/5970/4205/5594/7314/6233/5595/257397/4214 35 Human_coronavirus_229E R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 37/947 95/10654 1.3562954622751273e-15 4.3679669246604097e-14 2.16348344994494e-14 8454/6500/1147/2353/7311/1432/3725/4208/8945/23118/5518/1386/5601/351/9252/7099/4615/5602/4790/6885/5599/5528/5606/7316/57162/79155/10454/5608/5970/4205/695/5594/7314/6233/5595/257397/4214 37 Human_coronavirus_229E R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 37/947 95/10654 1.3562954622751273e-15 4.3679669246604097e-14 2.16348344994494e-14 8454/6500/1147/2353/7311/1432/3725/4208/8945/23118/5518/1386/5601/351/9252/7099/4615/5602/4790/6885/5599/5528/5606/7316/57162/79155/10454/5608/5970/4205/695/5594/7314/6233/5595/257397/4214 37 Human_coronavirus_229E R-HSA-450294 MAP kinase activation 30/947 64/10654 1.596304774963803e-15 5.0123969933863413e-14 2.4826740052726513e-14 8454/6500/1147/2353/7311/1432/3725/4208/8945/23118/5518/1386/5601/9252/5602/4790/6885/5599/5528/5606/7316/79155/10454/5608/4205/5594/7314/6233/5595/257397 30 Human_coronavirus_229E R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 36/947 92/10654 2.769928271258456e-15 8.485438801708831e-14 4.202895014926181e-14 8454/6500/1147/2353/7311/1432/3725/4208/8945/23118/5518/1386/5601/351/9252/7099/4615/5602/4790/6885/5599/5528/5606/7316/57162/79155/10454/5608/5970/4205/5594/7314/6233/5595/257397/4214 36 Human_coronavirus_229E R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 37/947 97/10654 2.9965012453948997e-15 8.856028787407569e-14 4.386450731945922e-14 8454/6500/1147/2353/3665/7311/1432/3725/4208/8945/23118/5518/1386/5601/351/9252/7099/4615/5602/4790/6885/5599/5528/5606/7316/57162/79155/10454/5608/5970/4205/5594/7314/6233/5595/257397/4214 37 Human_coronavirus_229E R-HSA-2262752 Cellular responses to stress 97/947 479/10654 3.0319206835869865e-15 8.856028787407569e-14 4.386450731945922e-14 2475/1912/5931/7295/2353/10294/1017/1030/7311/818/3303/3091/7013/5928/10370/367/9972/1432/7277/3725/2932/4928/1051/10013/1410/1387/815/472/10381/57122/5705/2034/1019/5601/23411/529/2908/8021/3313/10808/3309/6117/5602/8881/4790/29882/5599/2033/23512/7323/5606/5682/7266/7316/10376/9978/3312/7531/1029/7027/1915/6767/7321/3301/2113/405/5702/2146/5608/9531/6774/3569/7157/8453/5970/50507/1026/9532/23135/6667/10393/7422/5714/8091/5594/3308/7314/347688/10542/996/6233/5595/1778/6647/5717/1027/4194 97 Human_coronavirus_229E R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 37/947 98/10654 4.4118478002483836e-15 1.2313957415804378e-13 6.099186081746888e-14 8454/6500/1147/2353/7311/1432/3725/4208/8945/23118/5518/1386/5601/351/9252/7099/4615/5602/4790/6885/5599/5528/5606/7316/57162/79155/10454/5608/5970/4205/695/5594/7314/6233/5595/257397/4214 37 Human_coronavirus_229E R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 37/947 98/10654 4.4118478002483836e-15 1.2313957415804378e-13 6.099186081746888e-14 8454/6500/1147/2353/7311/1432/3725/4208/8945/23118/5518/1386/5601/351/9252/7099/4615/5602/4790/6885/5599/5528/5606/7316/57162/79155/10454/5608/5970/4205/695/5594/7314/6233/5595/257397/4214 37 Human_coronavirus_229E R-HSA-446652 Interleukin-1 family signaling 45/947 140/10654 5.2924261069310824e-15 1.4450624326750956e-13 7.157491599991464e-14 8454/6500/1147/5778/7311/834/5777/8945/23118/25930/5705/351/4088/4615/4790/6885/5599/84867/5784/5682/7316/57162/9978/26469/79155/5771/5782/5783/10454/5781/5702/5608/27178/6774/5970/5780/5714/3553/8878/7314/6233/54472/5775/5717/257397 45 Human_coronavirus_229E R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 16/947 19/10654 1.0123038365499712e-14 2.6488617056390914e-13 1.3119990513180545e-13 5295/7311/867/6464/1956/5290/5335/3845/7316/3265/1950/11140/6654/7314/6233/2885 16 Human_coronavirus_229E R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 16/947 19/10654 1.0123038365499712e-14 2.6488617056390914e-13 1.3119990513180545e-13 5295/7311/867/6464/1956/5290/5335/3845/7316/3265/1950/11140/6654/7314/6233/2885 16 Human_coronavirus_229E R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 39/947 111/10654 1.3005216914901082e-14 3.333582131656277e-13 1.651145692095927e-13 6158/7458/7311/6204/3646/26986/8663/6202/51386/9349/6188/6189/6232/6206/6194/6134/6169/6191/8665/6135/6147/6175/6129/6124/6207/6208/6222/6157/6137/6152/6136/1964/6193/6122/6133/6210/6205/6233/1975 39 Human_coronavirus_229E R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 39/947 112/10654 1.828620851192489e-14 4.593495578195532e-13 2.2751893116942336e-13 6158/7458/7311/6204/3646/8663/6202/51386/9349/6188/6189/6232/6206/6194/6134/6169/6191/8665/6135/6147/6175/6129/6124/9669/6207/6208/6222/6157/6137/6152/6136/1964/6193/6122/6133/6210/6205/6233/1975 39 Human_coronavirus_229E R-HSA-8953897 Cellular responses to external stimuli 97/947 493/10654 2.0519903634133805e-14 5.053529208720012e-13 2.503047068683814e-13 2475/1912/5931/7295/2353/10294/1017/1030/7311/818/3303/3091/7013/5928/10370/367/9972/1432/7277/3725/2932/4928/1051/10013/1410/1387/815/472/10381/57122/5705/2034/1019/5601/23411/529/2908/8021/3313/10808/3309/6117/5602/8881/4790/29882/5599/2033/23512/7323/5606/5682/7266/7316/10376/9978/3312/7531/1029/7027/1915/6767/7321/3301/2113/405/5702/2146/5608/9531/6774/3569/7157/8453/5970/50507/1026/9532/23135/6667/10393/7422/5714/8091/5594/3308/7314/347688/10542/996/6233/5595/1778/6647/5717/1027/4194 97 Human_coronavirus_229E R-HSA-9614085 FOXO-mediated transcription 29/947 65/10654 2.403731195510048e-14 5.805935349155038e-13 2.8757188998915755e-13 4089/7295/2308/8850/604/9314/10370/1387/23411/4088/857/2908/25942/6794/2290/2033/2309/10018/4802/3630/3065/3066/2660/1026/207/4087/10971/4303/1027 29 Human_coronavirus_229E R-HSA-72613 Eukaryotic Translation Initiation 40/947 119/10654 3.274188119484431e-14 7.615519033467491e-13 3.77201789203762e-13 6158/7458/7311/6204/3646/26986/8663/6202/51386/9349/6188/6189/6232/6206/6194/6134/6169/6191/8665/6135/6147/6175/6129/6124/9669/6207/6208/6222/6157/6137/6152/6136/1964/6193/6122/6133/6210/6205/6233/1975 40 Human_coronavirus_229E R-HSA-72737 Cap-dependent Translation Initiation 40/947 119/10654 3.274188119484431e-14 7.615519033467491e-13 3.77201789203762e-13 6158/7458/7311/6204/3646/26986/8663/6202/51386/9349/6188/6189/6232/6206/6194/6134/6169/6191/8665/6135/6147/6175/6129/6124/9669/6207/6208/6222/6157/6137/6152/6136/1964/6193/6122/6133/6210/6205/6233/1975 40 Human_coronavirus_229E R-HSA-1181150 Signaling by NODAL 16/947 20/10654 4.64489285030597e-14 1.060724621815327e-12 5.253840525417853e-13 4089/6997/7044/8928/92/4088/130399/10589/2309/4838/91/93/55997/4087/5045/10637 16 Human_coronavirus_229E R-HSA-448424 Interleukin-17 signaling 30/947 72/10654 8.059468602059957e-14 1.8076236721763045e-12 8.953281849280892e-13 8454/6500/1147/2353/7311/1432/3725/4208/8945/23118/5518/1386/5601/9252/5602/4790/6885/5599/5528/5606/7316/79155/10454/5608/4205/5594/7314/6233/5595/257397 30 Human_coronavirus_229E R-HSA-72689 Formation of a pool of free 40S subunits 36/947 101/10654 8.2518843191431e-14 1.8183099482181992e-12 9.006211694577234e-13 6158/7311/6204/3646/8663/6202/51386/9349/6188/6189/6232/6206/6194/6134/6169/6191/8665/6135/6147/6175/6129/6124/6207/6208/6222/6157/6137/6152/6136/1964/6193/6122/6133/6210/6205/6233 36 Human_coronavirus_229E R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 50/947 182/10654 1.6933651364355568e-13 3.667011398901826e-12 1.8162954548700802e-12 672/1912/115426/5905/367/9972/7341/4928/1387/10499/9063/6613/57122/10401/6670/1616/2908/25942/8021/6117/1487/2033/23512/8243/9126/3622/5468/7021/142/1029/28996/1655/3065/3066/7157/5970/3190/6996/9759/8648/9612/7421/6256/668/7329/5371/5111/2099/51588/8554 50 Human_coronavirus_229E R-HSA-156842 Eukaryotic Translation Elongation 34/947 93/10654 1.7333880205978543e-13 3.6900599218150934e-12 1.8277115435741873e-12 6158/7311/6204/6202/9349/6188/6189/6232/6206/6194/6134/6169/6191/6135/1938/6147/6175/6129/1915/6124/1933/6207/6208/6222/6157/6137/6152/6136/6193/6122/6133/6210/6205/6233 34 Human_coronavirus_229E R-HSA-9008059 Interleukin-37 signaling 16/947 21/10654 1.790312538762938e-13 3.7477209144770835e-12 1.8562714217699935e-12 5778/834/5777/25930/4088/84867/5784/26469/5771/5782/5783/5781/27178/6774/5780/5775 16 Human_coronavirus_229E R-HSA-156902 Peptide chain elongation 33/947 89/10654 2.4766636134878427e-13 5.099490981214312e-12 2.525812244299077e-12 6158/7311/6204/6202/9349/6188/6189/6232/6206/6194/6134/6169/6191/6135/1938/6147/6175/6129/1915/6124/6207/6208/6222/6157/6137/6152/6136/6193/6122/6133/6210/6205/6233 33 Human_coronavirus_229E R-HSA-168254 Influenza Infection 45/947 155/10654 3.3109811269191614e-13 6.707406928081398e-12 3.322223847214303e-12 6158/7514/7311/6204/3303/9972/9636/4928/6202/3837/3838/57122/9349/6188/6189/6232/8021/6206/6194/7040/6134/6169/6191/6135/6147/6175/293/6129/6124/5430/5901/6207/6208/6222/6157/6137/6152/6136/6193/6122/6133/6210/6205/6233/821 45 Human_coronavirus_229E R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 26/947 58/10654 4.654556557129294e-13 8.725556769782676e-12 4.321827062471976e-12 10014/8454/6500/22938/8850/7311/10013/1387/8841/26508/2033/7316/9978/2648/892/9611/3065/3066/4851/23462/9759/9612/1024/4609/7314/6233 26 Human_coronavirus_229E R-HSA-2644603 Signaling by NOTCH1 in Cancer 26/947 58/10654 4.654556557129294e-13 8.725556769782676e-12 4.321827062471976e-12 10014/8454/6500/22938/8850/7311/10013/1387/8841/26508/2033/7316/9978/2648/892/9611/3065/3066/4851/23462/9759/9612/1024/4609/7314/6233 26 Human_coronavirus_229E R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 26/947 58/10654 4.654556557129294e-13 8.725556769782676e-12 4.321827062471976e-12 10014/8454/6500/22938/8850/7311/10013/1387/8841/26508/2033/7316/9978/2648/892/9611/3065/3066/4851/23462/9759/9612/1024/4609/7314/6233 26 Human_coronavirus_229E R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 26/947 58/10654 4.654556557129294e-13 8.725556769782676e-12 4.321827062471976e-12 10014/8454/6500/22938/8850/7311/10013/1387/8841/26508/2033/7316/9978/2648/892/9611/3065/3066/4851/23462/9759/9612/1024/4609/7314/6233 26 Human_coronavirus_229E R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 26/947 58/10654 4.654556557129294e-13 8.725556769782676e-12 4.321827062471976e-12 10014/8454/6500/22938/8850/7311/10013/1387/8841/26508/2033/7316/9978/2648/892/9611/3065/3066/4851/23462/9759/9612/1024/4609/7314/6233 26 Human_coronavirus_229E R-HSA-8848021 Signaling by PTK6 25/947 54/10654 5.302571110350279e-13 9.652216397970942e-12 4.780807820315813e-12 1017/7311/3091/867/5921/2034/1019/387/1956/1796/6421/2908/10657/10457/3845/7316/595/3265/1950/6774/207/7314/6233/27043/1027 25 Human_coronavirus_229E R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 25/947 54/10654 5.302571110350279e-13 9.652216397970942e-12 4.780807820315813e-12 1017/7311/3091/867/5921/2034/1019/387/1956/1796/6421/2908/10657/10457/3845/7316/595/3265/1950/6774/207/7314/6233/27043/1027 25 Human_coronavirus_229E R-HSA-6807070 PTEN Regulation 42/947 140/10654 6.087430783317223e-13 1.0922590091209188e-11 5.410032470587187e-12 2475/10014/1912/57504/5931/7311/1460/5928/3725/6591/5705/1386/57459/8841/331/23512/5682/7316/5728/5468/7874/6615/5702/2146/3065/3066/7157/23028/10273/207/4734/5714/5371/5594/57167/7314/10542/6233/2122/5595/11060/5717 42 Human_coronavirus_229E R-HSA-2990846 SUMOylation 50/947 188/10654 6.609890944381774e-13 1.1692990177666913e-11 5.791616824506492e-12 672/1912/115426/5905/367/9972/7341/4928/1387/10499/9063/6613/57122/10401/6670/1616/2908/25942/8021/6117/1487/2033/23512/8243/9126/3622/5468/7021/142/1029/28996/1655/3065/3066/7157/5970/3190/6996/9759/8648/9612/7421/6256/668/7329/5371/5111/2099/51588/8554 50 Human_coronavirus_229E R-HSA-1980143 Signaling by NOTCH1 29/947 73/10654 9.080014154990133e-13 1.5839580248149454e-11 7.845450826899369e-12 10014/8454/6500/22938/8850/7311/3091/10013/1387/8841/26508/2033/7316/9978/2648/892/9611/3065/3066/4851/7088/83737/23462/9759/9612/1024/4609/7314/6233 29 Human_coronavirus_229E R-HSA-2871796 FCERI mediated MAPK activation 19/947 32/10654 1.0200623287275288e-12 1.7550661436736662e-11 8.692960869184854e-12 7409/2353/3725/4067/5601/6464/5602/5335/3845/5599/3265/5336/6850/5594/6654/2885/5595/7410/4214 19 Human_coronavirus_229E R-HSA-927802 Nonsense-Mediated Decay (NMD) 37/947 115/10654 1.3922920294438062e-12 2.3316250519752272e-11 1.1548695991597044e-11 6158/7311/6204/26986/6202/5518/9349/6188/6189/6232/9775/6206/6194/6134/6169/6191/55802/6135/4686/6147/6175/6129/6124/5520/6207/6208/6222/6157/6137/6152/6136/6193/6122/6133/6210/6205/6233 37 Human_coronavirus_229E R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 37/947 115/10654 1.3922920294438062e-12 2.3316250519752272e-11 1.1548695991597044e-11 6158/7311/6204/26986/6202/5518/9349/6188/6189/6232/9775/6206/6194/6134/6169/6191/55802/6135/4686/6147/6175/6129/6124/5520/6207/6208/6222/6157/6137/6152/6136/6193/6122/6133/6210/6205/6233 37 Human_coronavirus_229E R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 33/947 95/10654 2.0748701283411813e-12 3.428995896311215e-11 1.698404772644928e-11 6158/7311/6204/26986/6202/9349/6188/6189/6232/6206/6194/6134/6169/6191/6135/4686/6147/6175/6129/6124/6207/6208/6222/6157/6137/6152/6136/6193/6122/6133/6210/6205/6233 33 Human_coronavirus_229E R-HSA-177929 Signaling by EGFR 23/947 49/10654 3.173865873179844e-12 5.177111086641408e-11 2.5642580055355955e-11 5295/7311/867/6464/1956/5290/29924/55824/9146/5335/3845/7316/3265/1950/1445/5782/5781/2060/6654/7314/30011/6233/2885 23 Human_coronavirus_229E R-HSA-194138 Signaling by VEGF 35/947 107/10654 3.2900670742233564e-12 5.2978515964417124e-11 2.6240615936113414e-11 2475/5295/7409/3315/6093/3685/26999/5170/1432/3708/57761/5921/5590/387/3710/60/857/5290/5335/71/3845/2534/3690/1499/1500/3265/4690/9047/5603/7424/7423/207/3709/7422/7410 35 Human_coronavirus_229E R-HSA-3000170 Syndecan interactions 17/947 27/10654 4.219453086587734e-12 6.708396299688852e-11 3.3227138896380417e-11 1281/3685/1277/6383/6382/2247/7040/7448/2335/3690/6385/3688/87/7057/1278/3691/3693 17 Human_coronavirus_229E R-HSA-2129379 Molecules associated with elastic fibres 20/947 38/10654 5.572192625744953e-12 8.748342422419575e-11 4.33311294975693e-11 8425/3685/8516/650/655/7040/7448/2335/3690/4052/3688/3694/3696/7042/2200/7043/4054/3693/2192/652 20 Human_coronavirus_229E R-HSA-2408557 Selenocysteine synthesis 32/947 93/10654 6.024640860005331e-12 9.341912247119378e-11 4.627112083512867e-11 6158/7311/6204/6202/9349/6188/6189/6232/6206/6194/6134/6169/6191/6135/6147/6175/6129/79048/6124/6207/6208/6222/6157/6137/6152/6136/6193/6122/6133/6210/6205/6233 32 Human_coronavirus_229E R-HSA-168255 Influenza Life Cycle 41/947 144/10654 7.578671626908623e-12 1.157020798055117e-10 5.730801974946146e-11 6158/7514/7311/6204/3303/9972/4928/6202/3837/57122/9349/6188/6189/6232/8021/6206/6194/6134/6169/6191/6135/6147/6175/6129/6124/5430/5901/6207/6208/6222/6157/6137/6152/6136/6193/6122/6133/6210/6205/6233/821 41 Human_coronavirus_229E R-HSA-4420097 VEGFA-VEGFR2 Pathway 33/947 99/10654 7.645917694154038e-12 1.157020798055117e-10 5.730801974946146e-11 2475/5295/7409/3315/6093/3685/26999/5170/1432/3708/57761/5921/5590/387/3710/60/857/5290/5335/71/3845/2534/3690/1499/1500/3265/4690/9047/5603/207/3709/7422/7410 33 Human_coronavirus_229E R-HSA-192823 Viral mRNA Translation 31/947 89/10654 8.957135561454516e-12 1.3393050315698656e-10 6.633668066189998e-11 6158/7311/6204/6202/9349/6188/6189/6232/6206/6194/6134/6169/6191/6135/6147/6175/6129/6124/6207/6208/6222/6157/6137/6152/6136/6193/6122/6133/6210/6205/6233 31 Human_coronavirus_229E R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 30/947 84/10654 9.330212332593107e-12 1.3754541621922744e-10 6.812717145957377e-11 7124/9314/1052/1051/1387/10499/7471/23054/1019/10001/8841/7040/688/4790/2033/5468/9967/892/9611/6721/51129/51586/8202/1050/5970/8648/9612/6256/1024/9862 30 Human_coronavirus_229E R-HSA-6806834 Signaling by MET 29/947 79/10654 9.417918626475764e-12 1.3754541621922744e-10 6.812717145957377e-11 5295/1281/3082/7311/867/1277/6464/1280/5290/3912/9146/2335/3845/3688/7316/3265/5771/5781/6774/1278/10048/3911/3915/2060/6654/7314/30011/6233/2885 29 Human_coronavirus_229E R-HSA-1643713 Signaling by EGFR in Cancer 16/947 25/10654 1.2751378600087357e-11 1.8408886806562895e-10 9.118045677739417e-11 5295/7311/867/6464/1956/5290/5335/3845/7316/3265/1950/11140/6654/7314/6233/2885 16 Human_coronavirus_229E R-HSA-9010553 Regulation of expression of SLITs and ROBOs 45/947 171/10654 1.4227470464152929e-11 2.0306480571563727e-10 1.0057936655878445e-10 6158/7311/6204/26986/6202/5705/3670/9349/6188/6189/6232/9775/6206/6194/6134/6169/6191/6135/5682/4686/7316/6147/6175/9978/6129/6124/5702/8453/6207/89884/6208/6222/6157/6137/5714/6152/6136/6193/6122/6133/6210/6205/7314/6233/5717 45 Human_coronavirus_229E R-HSA-1566948 Elastic fibre formation 21/947 45/10654 3.239580031484126e-11 4.57181181971243e-10 2.2644492000084196e-10 8425/3685/8516/650/655/7040/7448/2335/3690/4052/3688/3694/3696/7042/2200/7043/4054/3693/5045/2192/652 21 Human_coronavirus_229E R-HSA-72764 Eukaryotic Translation Termination 31/947 93/10654 3.308318885659738e-11 4.6169428004318123e-10 2.2868028788595383e-10 6158/7311/6204/6202/9349/6188/6189/6232/6206/6194/6134/6169/6191/6135/6147/6175/6129/6124/6207/6208/6222/6157/6137/6152/6136/6193/6122/6133/6210/6205/6233 31 Human_coronavirus_229E R-HSA-1227986 Signaling by ERBB2 22/947 50/10654 4.678428282844209e-11 6.457259256321238e-10 3.198324019850697e-10 5295/7311/387/8065/6464/1956/5290/5335/3845/2534/7316/3265/26469/1950/5782/10273/207/11140/6654/7314/6233/2885 22 Human_coronavirus_229E R-HSA-8939211 ESR-mediated signaling 52/947 223/10654 5.258755166780326e-11 7.179344010300097e-10 3.5559774640356666e-10 5295/3727/3315/7514/1025/2353/51523/8850/5170/3725/1387/4318/10499/3838/5590/1386/6464/1956/857/5290/3845/2033/4435/2309/904/4313/8243/9126/595/3276/3265/1950/9687/865/8312/1655/3065/8202/5430/8648/23028/861/207/6667/2625/2099/5594/4609/6722/5595/7528/1027 52 Human_coronavirus_229E R-HSA-2219528 PI3K/AKT Signaling in Cancer 32/947 101/10654 7.250097400941611e-11 9.791529393099638e-10 4.849810485519516e-10 2475/5295/7249/7409/3082/930/1147/2308/5170/2932/3932/2931/5293/5155/1956/2247/5290/118788/3164/3667/2534/2309/391/5728/1950/5781/1026/207/2099/4303/2885/1027 32 Human_coronavirus_229E R-HSA-5637810 Constitutive Signaling by EGFRvIII 12/947 15/10654 8.057741080569808e-11 1.0653181891784926e-9 5.27659277409059e-10 5295/867/6464/1956/5290/5335/3845/3265/1950/11140/6654/2885 12 Human_coronavirus_229E R-HSA-5637812 Signaling by EGFRvIII in Cancer 12/947 15/10654 8.057741080569808e-11 1.0653181891784926e-9 5.27659277409059e-10 5295/867/6464/1956/5290/5335/3845/3265/1950/11140/6654/2885 12 Human_coronavirus_229E R-HSA-400253 Circadian Clock 26/947 70/10654 8.26948722337916e-11 1.0819245783921067e-9 5.358845338834521e-10 8454/6500/7311/3091/4208/8945/1387/10499/23054/1386/23411/8841/2908/2033/5936/7316/1453/9611/5501/8648/6256/5499/5500/7314/6233/5054 26 Human_coronavirus_229E R-HSA-452723 Transcriptional regulation of pluripotent stem cells 15/947 24/10654 9.339118375576917e-11 1.2092714102808874e-9 5.989602778042276e-10 4089/63978/6997/9314/5087/79727/79923/2034/6657/2247/5460/6774/84891/4087/57167 15 Human_coronavirus_229E R-HSA-8943724 Regulation of PTEN gene transcription 24/947 61/10654 1.078933416863515e-10 1.3827962975311987e-9 6.849083237017587e-10 2475/10014/1912/57504/5931/5928/3725/6591/1386/57459/8841/23512/5468/6615/2146/3065/3066/7157/23028/5594/57167/10542/2122/5595 24 Human_coronavirus_229E R-HSA-1502540 Signaling by Activin 11/947 13/10654 1.7109776535989685e-10 2.163751320411529e-9 1.0717206087522743e-9 4089/8928/92/4088/130399/10589/91/93/3624/4087/3625 11 Human_coronavirus_229E R-HSA-69231 Cyclin D associated events in G1 20/947 44/10654 1.7399592624328378e-10 2.163751320411529e-9 1.0717206087522743e-9 8454/6500/1030/7311/5518/1019/4067/6502/1874/7316/595/1875/1029/7027/5520/1026/5933/7314/6233/1027 20 Human_coronavirus_229E R-HSA-69236 G1 Phase 20/947 44/10654 1.7399592624328378e-10 2.163751320411529e-9 1.0717206087522743e-9 8454/6500/1030/7311/5518/1019/4067/6502/1874/7316/595/1875/1029/7027/5520/1026/5933/7314/6233/1027 20 Human_coronavirus_229E R-HSA-195721 Signaling by WNT 66/947 331/10654 2.0992445771259546e-10 2.5849521459511756e-9 1.2803442157703192e-9 50855/8454/6500/7514/57154/7311/6736/9070/1460/2932/51176/8945/1387/815/7471/3708/5518/5705/9580/387/3710/1455/857/6657/160/331/8607/64750/6662/22943/3845/6885/1487/2033/5528/6597/5682/7316/1499/9978/8312/51701/864/5529/5702/3065/7088/8313/207/8085/3709/83439/5714/6934/83595/57680/4609/7314/6233/1855/4221/1488/4041/5717/6932/5929 66 Human_coronavirus_229E R-HSA-72649 Translation initiation complex formation 23/947 58/10654 2.192950506039144e-10 2.6741221704710337e-9 1.3245107297589515e-9 7458/6204/3646/26986/8663/6202/51386/6188/6189/6232/6206/6194/6191/8665/6207/6208/6222/1964/6193/6210/6205/6233/1975 23 Human_coronavirus_229E R-HSA-3371556 Cellular response to heat stress 29/947 89/10654 2.6593159211452106e-10 3.2116353816907543e-9 1.5907446451384811e-9 2475/818/3303/9972/2932/4928/10013/1410/1387/815/472/57122/23411/8021/3313/10808/3309/6117/2033/7266/3312/7531/1915/6767/9531/9532/5594/3308/5595 29 Human_coronavirus_229E R-HSA-912631 Regulation of signaling by CBL 14/947 22/10654 2.844609807072454e-10 3.4026951596980975e-9 1.6853778405812738e-9 5295/7409/7311/29760/867/5293/4067/5290/2534/7316/6850/7314/6233/2885 14 Human_coronavirus_229E R-HSA-3899300 SUMOylation of transcription cofactors 20/947 45/10654 2.8727602698603603e-10 3.4039499046647287e-9 1.6859993242179474e-9 1912/115426/7341/1387/10499/9063/6613/10401/1616/25942/1487/2033/3622/28996/1655/8648/9612/7329/51588/8554 20 Human_coronavirus_229E R-HSA-201681 TCF dependent signaling in response to WNT 52/947 233/10654 2.909504706547462e-10 3.415269076096834e-9 1.691605786098918e-9 7514/7311/6736/9070/1460/2932/51176/8945/1387/7471/5518/5705/9580/1455/857/6657/331/8607/64750/6662/22943/1487/2033/5528/6597/5682/7316/1499/9978/8312/864/5529/5702/3065/7088/8313/207/8085/83439/5714/6934/83595/57680/4609/7314/6233/1855/4221/4041/5717/6932/5929 52 Human_coronavirus_229E R-HSA-5688426 Deubiquitination 61/947 297/10654 3.0242810919684724e-10 3.51712689954852e-9 1.7420566523911962e-9 4089/672/7048/4086/8850/7128/7311/3091/367/5705/7046/6502/387/4088/7706/60/7040/8607/64750/10617/9146/6885/2033/5682/8239/7316/5728/1540/2648/993/8312/79155/7874/80124/10454/7321/991/5702/51377/7157/9958/8313/8237/4087/63891/84749/5714/7375/4092/55611/2625/8678/9817/2099/4303/4609/7314/6233/5717/7528/4194 61 Human_coronavirus_229E R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 23/947 59/10654 3.295579171359426e-10 3.7974747148875586e-9 1.880914814363516e-9 7458/6204/3646/26986/8663/6202/51386/6188/6189/6232/6206/6194/6191/8665/6207/6208/6222/1964/6193/6210/6205/6233/1975 23 Human_coronavirus_229E R-HSA-3000178 ECM proteoglycans 26/947 76/10654 6.754286676011632e-10 7.712167331882372e-9 3.819888445476435e-9 1281/3685/4060/8516/1277/351/54829/1280/3912/7040/633/7448/2335/3690/3688/3694/6678/7042/2331/1278/3911/3915/7043/3693/1634/5054 26 Human_coronavirus_229E R-HSA-376176 Signaling by ROBO receptors 49/947 218/10654 7.400704346232036e-10 8.374130323303997e-9 4.147763175555365e-9 6158/7311/6204/26986/6202/5705/387/3670/9349/6188/6189/6232/9775/6206/6194/6134/6169/6191/6135/5682/4686/7316/2817/6147/6175/9978/6129/4690/6124/5702/8453/6207/89884/6208/6222/6157/6137/5714/6152/6136/6193/6122/6133/6210/6205/6654/7314/6233/5717 49 Human_coronavirus_229E R-HSA-8878171 Transcriptional regulation by RUNX1 52/947 239/10654 7.648824042981716e-10 8.577609819629494e-9 4.248547941167476e-9 1912/8850/7311/9070/1460/860/1387/6938/5705/6599/25942/5196/2624/8289/100506658/11091/10138/2033/6597/5682/7316/595/50943/3276/6601/865/6929/8312/28996/5079/3458/5781/7057/5702/3065/83737/640/861/8085/10413/5714/5371/23309/2625/2099/57492/7314/6233/55170/5717/5929/9757 52 Human_coronavirus_229E R-HSA-195253 Degradation of beta-catenin by the destruction complex 27/947 82/10654 8.452092703208301e-10 9.394538438256307e-9 4.653178190587896e-9 8454/6500/7311/2932/51176/8945/5518/5705/1487/5528/5682/7316/1499/9978/8312/5529/5702/3065/7088/83439/5714/6934/7314/6233/1488/5717/6932 27 Human_coronavirus_229E R-HSA-168273 Influenza Viral RNA Transcription and Replication 36/947 134/10654 8.579409634967455e-10 9.452402194315021e-9 4.681838498860357e-9 6158/7311/6204/9972/4928/6202/57122/9349/6188/6189/6232/8021/6206/6194/6134/6169/6191/6135/6147/6175/6129/6124/5430/6207/6208/6222/6157/6137/6152/6136/6193/6122/6133/6210/6205/6233 36 Human_coronavirus_229E R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 12/947 17/10654 9.255662643985453e-10 1.0108793287691938e-8 5.006953430293275e-9 4089/2308/9314/4088/857/2290/2309/2660/1026/4087/4303/1027 12 Human_coronavirus_229E R-HSA-114604 GPVI-mediated activation cascade 17/947 35/10654 1.1412259341793779e-9 1.2356722183873264e-8 6.120367759528242e-9 5295/7409/5170/5777/3932/5590/4067/1277/387/5290/2534/391/5781/5336/1278/6850/7410 17 Human_coronavirus_229E R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 32/947 112/10654 1.392393786690448e-9 1.4947406804129936e-8 7.4035513084485355e-9 6158/7311/6204/6184/6202/9349/6188/6189/6232/6206/6194/6134/6169/6191/6135/6147/6175/6129/6124/6207/6208/6222/6157/6137/6152/6136/6193/6122/6133/6210/6205/6233 32 Human_coronavirus_229E R-HSA-1474244 Extracellular matrix organization 60/947 301/10654 1.4513010459221736e-9 1.5387256904274825e-8 7.621412026840783e-9 2266/1281/8425/3685/4060/4318/7076/4312/5155/8516/2243/1277/351/6383/54829/7450/6382/999/650/1280/2247/2244/3912/655/7040/633/7448/50848/2335/3690/4052/5650/6385/3688/3694/4313/3696/6678/7042/2200/5340/87/7057/2331/667/1278/3691/5339/3911/3915/823/7043/4054/3693/2/5045/1634/2192/652/5054 60 Human_coronavirus_229E R-HSA-453279 Mitotic G1-G1/S phases 38/947 149/10654 1.4773815000400667e-9 1.5387256904274825e-8 7.621412026840783e-9 8454/6500/1017/1030/7311/5928/4173/5518/5705/1019/4067/6502/4149/6117/1874/5682/7316/595/1875/1029/7027/993/7465/5702/3065/5520/1859/1026/207/5933/5714/5111/4176/4609/7314/6233/5717/1027 38 Human_coronavirus_229E R-HSA-1236394 Signaling by ERBB4 22/947 58/10654 1.4823710871156481e-9 1.5387256904274825e-8 7.621412026840783e-9 5295/7311/23118/51741/6464/1956/5290/3845/6678/7316/3265/1950/9611/11059/83737/4734/10413/2099/6654/7314/6233/2885 22 Human_coronavirus_229E R-HSA-72702 Ribosomal scanning and start codon recognition 22/947 58/10654 1.4823710871156481e-9 1.5387256904274825e-8 7.621412026840783e-9 7458/6204/3646/8663/6202/51386/6188/6189/6232/6206/6194/6191/8665/6207/6208/6222/1964/6193/6210/6205/6233/1975 22 Human_coronavirus_229E R-HSA-2559583 Cellular Senescence 45/947 195/10654 1.519606575347247e-9 1.564447425111592e-8 7.748813511908741e-9 1912/5931/7295/2353/1017/1030/7311/7013/5928/1432/3725/1051/472/1019/5601/5602/8881/4790/29882/5599/23512/5606/7316/1029/7027/7321/2113/2146/5608/6774/3569/7157/5970/1026/23135/6667/10393/8091/5594/7314/996/6233/5595/1027/4194 45 Human_coronavirus_229E R-HSA-5654741 Signaling by FGFR3 18/947 40/10654 1.7603522021174286e-9 1.7975628990727563e-8 8.903450162185711e-9 5295/7311/867/5518/6464/2247/5290/5335/3845/7316/3265/5781/5594/6654/7314/6233/2885/5595 18 Human_coronavirus_229E R-HSA-3247509 Chromatin modifying enzymes 56/947 274/10654 1.9971452853688037e-9 2.0067315827385738e-8 9.939476746551267e-9 57504/5931/84444/80854/8850/284058/9070/5928/1387/10499/1019/1386/57459/8841/6599/60/8607/8289/11091/4790/7403/2033/55870/79595/23512/6597/8819/595/3276/2648/6601/9611/55729/10284/8242/2146/3065/3066/10856/5970/79084/8648/9612/23028/8085/29072/23135/63976/6839/57492/2122/55170/79723/5929/9757/22992 56 Human_coronavirus_229E R-HSA-4839726 Chromatin organization 56/947 274/10654 1.9971452853688037e-9 2.0067315827385738e-8 9.939476746551267e-9 57504/5931/84444/80854/8850/284058/9070/5928/1387/10499/1019/1386/57459/8841/6599/60/8607/8289/11091/4790/7403/2033/55870/79595/23512/6597/8819/595/3276/2648/6601/9611/55729/10284/8242/2146/3065/3066/10856/5970/79084/8648/9612/23028/8085/29072/23135/63976/6839/57492/2122/55170/79723/5929/9757/22992 56 Human_coronavirus_229E R-HSA-8941326 RUNX2 regulates bone development 16/947 32/10654 2.0591715369370026e-9 2.05263448443879e-8 1.0166836911693973e-8 4089/4086/25937/367/860/10013/1277/8841/865/23462/9759/4091/10413/5594/5595/25925 16 Human_coronavirus_229E R-HSA-3000171 Non-integrin membrane-ECM interactions 22/947 59/10654 2.167827566563037e-9 2.143930254805649e-8 1.0619031013997139e-8 1281/3685/5155/1277/6383/6382/1280/2247/3912/7040/7448/2335/3690/6385/3688/87/7057/1278/3691/3911/3915/3693 22 Human_coronavirus_229E R-HSA-5654743 Signaling by FGFR4 18/947 41/10654 2.8794174393344957e-9 2.8254283623469738e-8 1.3994537061239202e-8 5295/7311/867/5518/6464/2247/5290/5335/3845/7316/3265/5781/5594/6654/7314/6233/2885/5595 18 Human_coronavirus_229E R-HSA-9006931 Signaling by Nuclear Receptors 59/947 299/10654 2.986481234363727e-9 2.9077677754735202e-8 1.4402369722635353e-8 5295/3727/3315/7514/1025/2353/51523/8850/5170/5915/3725/1387/4318/10499/3838/5590/1386/6464/1956/8841/857/5467/5290/3845/2033/4435/2309/904/4313/8243/9126/595/3276/3265/1950/9687/9611/865/8312/5160/1655/3065/8202/5430/8648/9612/23028/861/207/6256/6667/2625/2099/5594/4609/6722/5595/7528/1027 59 Human_coronavirus_229E R-HSA-450341 Activation of the AP-1 family of transcription factors 9/947 10/10654 3.0800664702333575e-9 2.9758180666254592e-8 1.4739427400064084e-8 2353/1432/3725/1386/5601/5602/5599/5594/5595 9 Human_coronavirus_229E R-HSA-157118 Signaling by NOTCH 50/947 235/10654 3.6364380725432737e-9 3.4865390985605744e-8 1.7269063084556646e-8 10014/8454/6500/22938/8850/7311/3091/5087/3725/10013/1387/5705/1956/4088/8841/59/26508/2033/5682/4855/7316/595/9978/2648/1950/892/9611/7027/5702/3065/3066/4851/7157/7088/83737/23462/9759/9612/861/207/1024/4904/5714/6772/5045/4609/7314/6233/11060/5717 50 Human_coronavirus_229E R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 20/947 51/10654 4.186188461196468e-9 3.983221747926336e-8 1.9729165714251295e-8 6204/3646/8663/6202/51386/6188/6189/6232/6206/6194/6191/8665/6207/6208/6222/1964/6193/6210/6205/6233 20 Human_coronavirus_229E R-HSA-69242 S Phase 39/947 161/10654 4.425721859655811e-9 4.179478688517067e-8 2.0701239565149066e-8 8454/6500/1017/7311/5928/2932/4173/5705/1019/6502/4149/6117/8881/29882/1874/5682/8243/9126/7316/595/9978/1875/7027/993/7465/7321/5702/1026/207/10393/5714/5111/4176/4609/7314/996/6233/5717/1027 39 Human_coronavirus_229E R-HSA-5621481 C-type lectin receptors (CLRs) 36/947 142/10654 4.749771460475979e-9 4.45202459280435e-8 2.2051177793725872e-8 8454/6500/1147/7311/5971/5170/8945/23118/1387/3708/5705/4586/4067/9252/3710/4790/3845/6885/2534/2033/5682/7316/3265/10454/7321/5702/5970/5336/6850/3709/5714/3553/7314/6233/5717/257397 36 Human_coronavirus_229E R-HSA-69202 Cyclin E associated events during G1/S transition 26/947 83/10654 5.775075070173704e-9 5.343904351561065e-8 2.64687183353385e-8 8454/6500/1017/7311/5928/5705/1019/6502/4149/1874/5682/7316/595/1875/7027/993/7465/5702/1026/207/5714/4609/7314/6233/5717/1027 26 Human_coronavirus_229E R-HSA-2408522 Selenoamino acid metabolism 32/947 118/10654 5.786393246913256e-9 5.343904351561065e-8 2.64687183353385e-8 6158/7311/6204/6202/9349/6188/6189/6232/6206/6194/6134/6169/6191/6135/6147/6175/6129/79048/6124/6207/6208/6222/6157/6137/6152/6136/6193/6122/6133/6210/6205/6233 32 Human_coronavirus_229E R-HSA-2424491 DAP12 signaling 15/947 30/10654 6.637050155538159e-9 6.040677532866615e-8 2.9919882852197196e-8 5295/3932/6464/5290/5335/3845/2534/7305/3265/5336/6850/695/6654/2885/7410 15 Human_coronavirus_229E R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 15/947 30/10654 6.637050155538159e-9 6.040677532866615e-8 2.9919882852197196e-8 7124/1147/7128/7311/23118/331/6885/7316/1540/10454/55072/7375/7314/6233/257397 15 Human_coronavirus_229E R-HSA-8939902 Regulation of RUNX2 expression and activity 24/947 73/10654 7.593594040005558e-9 6.861549722479843e-8 3.3985718119222144e-8 8454/6500/57154/7311/2932/860/5705/6502/650/2908/5682/7316/9978/865/5702/11059/10273/579/5714/6772/2099/7314/6233/5717 24 Human_coronavirus_229E R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 19/947 48/10654 8.52778459412324e-9 7.650641035870564e-8 3.789414056486342e-8 5295/7409/7311/29760/5777/867/5293/4067/6464/5290/2534/7316/5781/6850/6654/7314/6233/2885/3635 19 Human_coronavirus_229E R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 26/947 85/10654 1.0129087621925688e-8 9.022790108608981e-8 4.469048738005287e-8 8454/6500/1017/7311/5928/5705/1019/6502/4149/1874/5682/7316/595/1875/7027/993/7465/5702/1026/207/5714/4609/7314/6233/5717/1027 26 Human_coronavirus_229E R-HSA-3232118 SUMOylation of transcription factors 12/947 20/10654 1.4629884138801134e-8 1.2849744390443513e-7 6.364564980516356e-8 7341/9063/6613/10401/6670/7021/1029/7157/668/7329/51588/8554 12 Human_coronavirus_229E R-HSA-8876384 Listeria monocytogenes entry into host cells 12/947 20/10654 1.4629884138801134e-8 1.2849744390443513e-7 6.364564980516356e-8 7311/867/999/9146/7316/1499/1500/2060/7314/30011/6233/2885 12 Human_coronavirus_229E R-HSA-1433617 Regulation of signaling by NODAL 9/947 11/10654 1.559796787723649e-8 1.3604894204034048e-7 6.738595771525412e-8 6997/7044/92/130399/4838/91/93/55997/10637 9 Human_coronavirus_229E R-HSA-168638 NOD1/2 Signaling Pathway 16/947 36/10654 1.7778840759310157e-8 1.540015447840935e-7 7.627800282215829e-8 1147/7128/7311/834/1432/23118/6885/7316/1540/5603/10454/5608/83737/7314/6233/257397 16 Human_coronavirus_229E R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 20/947 55/10654 1.9311694549614533e-8 1.6613348187887572e-7 8.228703301241666e-8 7295/1147/7128/7311/834/1432/23118/351/4790/6885/7316/1540/5603/10454/5608/5970/83737/7314/6233/257397 20 Human_coronavirus_229E R-HSA-350054 Notch-HLH transcription pathway 14/947 28/10654 2.142003892975514e-8 1.8301747548144527e-7 9.064978881120865e-8 10014/22938/8850/10013/1387/8841/4855/2648/9611/3065/3066/4851/9759/9612 14 Human_coronavirus_229E R-HSA-69206 G1/S Transition 33/947 131/10654 2.46413406387183e-8 2.0911840433939315e-7 1.0357775474738632e-7 8454/6500/1017/7311/5928/4173/5518/5705/1019/6502/4149/6117/1874/5682/7316/595/1875/7027/993/7465/5702/3065/1026/207/5933/5714/5111/4176/4609/7314/6233/5717/1027 33 Human_coronavirus_229E R-HSA-9009391 Extra-nuclear estrogen signaling 24/947 77/10654 2.4814327677820657e-8 2.091731245861929e-7 1.036048580543413e-7 5295/3315/7514/2353/5170/4318/5590/6464/1956/857/5290/3845/2309/4313/595/3276/3265/1950/207/2099/5594/6722/5595/1027 24 Human_coronavirus_229E R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 32/947 125/10654 2.6475169740567816e-8 2.216854212943545e-7 1.0980228292403914e-7 2266/5069/7076/3479/4312/2243/197/60676/351/6383/57104/3912/5265/3827/338/7018/2335/2153/4052/4313/213/2200/5624/5340/2621/3569/3481/3915/2147/5768/652/4221 32 Human_coronavirus_229E R-HSA-5607764 CLEC7A (Dectin-1) signaling 28/947 101/10654 3.0687404316643605e-8 2.5525417100466467e-7 1.2642911084793567e-7 8454/6500/1147/7311/5971/5170/8945/23118/3708/5705/3710/4790/6885/5682/7316/10454/7321/5702/5970/5336/6850/3709/5714/3553/7314/6233/5717/257397 28 Human_coronavirus_229E R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 13/947 25/10654 3.7676370172600266e-8 3.1132579563674957e-7 1.5420176434907727e-7 2475/7249/1147/2308/5170/2932/2931/3164/2309/1026/207/4303/1027 13 Human_coronavirus_229E R-HSA-186763 Downstream signal transduction 14/947 29/10654 3.803886312725511e-8 3.1226674567210733e-7 1.5466782324188353e-7 5295/5155/5921/5290/6778/5335/3845/3265/4690/5781/6774/6772/6654/2885 14 Human_coronavirus_229E R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 16/947 38/10654 4.56025435250658e-8 3.719272381005367e-7 1.8421806714500266e-7 10370/7341/51741/1387/5308/1956/2033/4435/7021/1026/7329/7422/2099/4609/3329/7528 16 Human_coronavirus_229E R-HSA-9020702 Interleukin-1 signaling 28/947 103/10654 4.882490106961404e-8 3.9563919834474343e-7 1.9596276082948658e-7 8454/6500/1147/7311/8945/23118/5705/351/4615/4790/6885/5682/7316/57162/9978/79155/10454/5702/5608/5970/5714/3553/8878/7314/6233/54472/5717/257397 28 Human_coronavirus_229E R-HSA-186797 Signaling by PDGF 20/947 58/10654 5.454200761770276e-8 4.391330869732991e-7 2.175055769369928e-7 5295/1281/5155/5921/1280/5290/6778/5335/3845/3265/5340/4690/5782/5781/7057/6774/6772/5045/6654/2885 20 Human_coronavirus_229E R-HSA-210990 PECAM1 interactions 9/947 12/10654 5.745172354464314e-8 4.5961378835714514e-7 2.2764980633512638e-7 3685/5777/3932/4067/5335/2534/3690/5781/3635 9 Human_coronavirus_229E R-HSA-199418 Negative regulation of the PI3K/AKT network 29/947 110/10654 5.910590749384262e-8 4.6985455577383754e-7 2.3272212744077942e-7 5295/7409/3082/930/3932/3643/5293/5518/5155/57761/1956/2247/5290/118788/4615/3667/2534/5528/391/5728/1950/5529/5781/3630/207/2099/5594/2885/5595 29 Human_coronavirus_229E R-HSA-4090294 SUMOylation of intracellular receptors 14/947 30/10654 6.551544947750739e-8 5.175308461871024e-7 2.563365153340408e-7 367/7341/9063/6613/10401/2908/5468/9759/7421/6256/7329/2099/51588/8554 14 Human_coronavirus_229E R-HSA-5683057 MAPK family signaling cascades 55/947 294/10654 7.074040907738236e-8 5.538316079669341e-7 2.743165272447688e-7 88/2266/3315/3082/7514/2308/7311/818/2118/3725/10256/815/5518/5155/5921/5705/2243/7450/6464/1956/6711/60/2247/2244/3667/71/2335/3845/2534/3690/5528/2309/5682/7316/3265/9978/1950/5529/1445/7297/5781/5702/8202/3569/10048/5597/5714/5594/6654/4609/7314/6233/2885/5595/5717 55 Human_coronavirus_229E R-HSA-76009 Platelet Aggregation (Plug Formation) 16/947 39/10654 7.099274592569778e-8 5.538316079669341e-7 2.743165272447688e-7 2266/5170/2243/1277/7450/6464/2244/2335/3690/1445/1278/6850/207/2147/6654/2885 16 Human_coronavirus_229E R-HSA-5689880 Ub-specific processing proteases 45/947 220/10654 7.676725287265575e-8 5.951831457287384e-7 2.9479822253242075e-7 4089/4086/7311/3091/367/5705/7046/6502/4088/8607/64750/9146/6885/5682/8239/7316/5728/1540/2648/993/8312/7874/10454/991/5702/7157/9958/8313/8237/4087/63891/84749/5714/7375/4092/55611/2625/8678/9817/4303/4609/7314/6233/5717/4194 45 Human_coronavirus_229E R-HSA-9012852 Signaling by NOTCH3 18/947 49/10654 8.278613686333799e-8 6.379103552168865e-7 3.1596129729565873e-7 22938/8850/7311/5087/1387/1956/26508/2033/7316/2648/1950/4851/23462/4904/6772/7314/6233/11060 18 Human_coronavirus_229E R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 14/947 31/10654 1.0974531719991678e-7 8.404885268481431e-7 4.1629963071341993e-7 2353/1432/3725/4208/5518/1386/5601/9252/5602/5599/5528/4205/5594/5595 14 Human_coronavirus_229E R-HSA-5654736 Signaling by FGFR1 18/947 50/10654 1.1871521167760322e-7 9.036745810125433e-7 4.475961091002457e-7 5295/7311/867/5518/6464/2247/5290/5335/3845/7316/3265/5781/5594/6654/7314/6233/2885/5595 18 Human_coronavirus_229E R-HSA-354192 Integrin alphaIIb beta3 signaling 13/947 27/10654 1.2270767998357528e-7 9.228793177207818e-7 4.571083445968673e-7 2266/5170/2243/7450/6464/2244/2335/3690/1445/6850/207/6654/2885 13 Human_coronavirus_229E R-HSA-9006921 Integrin signaling 13/947 27/10654 1.2270767998357528e-7 9.228793177207818e-7 4.571083445968673e-7 2266/5170/2243/7450/6464/2244/2335/3690/1445/6850/207/6654/2885 13 Human_coronavirus_229E R-HSA-6804757 Regulation of TP53 Degradation 15/947 36/10654 1.4285565330606665e-7 1.04649543161326e-6 5.183362387558135e-7 2475/1017/7311/5170/5518/472/1616/7316/1029/7874/7157/207/7314/6233/4194 15 Human_coronavirus_229E R-HSA-1295596 Spry regulation of FGF signaling 10/947 16/10654 1.4323274832093174e-7 1.04649543161326e-6 5.183362387558135e-7 7311/867/5518/7316/5781/5594/7314/6233/2885/5595 10 Human_coronavirus_229E R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 10/947 16/10654 1.4323274832093174e-7 1.04649543161326e-6 5.183362387558135e-7 8454/6500/1147/7311/8945/4790/7316/79155/7314/6233 10 Human_coronavirus_229E R-HSA-9614657 FOXO-mediated transcription of cell death genes 10/947 16/10654 1.4323274832093174e-7 1.04649543161326e-6 5.183362387558135e-7 2308/604/10370/1387/6794/2033/2309/10018/4802/4303 10 Human_coronavirus_229E R-HSA-74749 Signal attenuation 8/947 10/10654 1.4497627794642296e-7 1.04649543161326e-6 5.183362387558135e-7 3643/6464/3667/3630/5594/6654/2885/5595 8 Human_coronavirus_229E R-HSA-937042 IRAK2 mediated activation of TAK1 complex 8/947 10/10654 1.4497627794642296e-7 1.04649543161326e-6 5.183362387558135e-7 7311/23118/6885/7316/10454/7314/6233/257397 8 Human_coronavirus_229E R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 8/947 10/10654 1.4497627794642296e-7 1.04649543161326e-6 5.183362387558135e-7 7295/2308/8850/1387/23411/2033/2309/4303 8 Human_coronavirus_229E R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 23/947 78/10654 1.5220237514171574e-7 1.0923781895885427e-6 5.410622779473925e-7 1147/3665/7128/7311/9636/1387/351/7706/5300/4790/2033/7323/7316/1540/7321/5970/83737/3661/51191/7314/6233/10010/4214 23 Human_coronavirus_229E R-HSA-73887 Death Receptor Signalling 33/947 141/10654 1.6448823002122294e-7 1.1738478233332728e-6 5.814147364984615e-7 7409/7124/1147/7128/7311/23118/26574/387/8841/23370/4615/331/4790/6885/5599/8837/7316/1540/10018/7531/11108/10454/3065/3066/5970/55072/7375/8878/6654/7314/6233/257397/7410 33 Human_coronavirus_229E R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 27/947 103/10654 1.913679575396339e-7 1.357955676100453e-6 6.726045965264564e-7 5295/7409/3082/930/3932/3643/5293/5518/5155/1956/2247/5290/118788/4615/3667/2534/5528/391/1950/5529/5781/3630/207/2099/5594/2885/5595 27 Human_coronavirus_229E R-HSA-6806003 Regulation of TP53 Expression and Degradation 15/947 37/10654 2.2064983683197571e-7 1.5569449160728175e-6 7.711653079106899e-7 2475/1017/7311/5170/5518/472/1616/7316/1029/7874/7157/207/7314/6233/4194 15 Human_coronavirus_229E R-HSA-8940973 RUNX2 regulates osteoblast differentiation 12/947 24/10654 2.2426100228479032e-7 1.573585580277635e-6 7.794075410191773e-7 25937/367/860/10013/1277/8841/865/23462/10413/5594/5595/25925 12 Human_coronavirus_229E R-HSA-2559585 Oncogene Induced Senescence 14/947 33/10654 2.8597449291879697e-7 1.99546646170005e-6 9.883679842982984e-7 1030/7311/1019/7316/1029/7027/2113/7157/6667/5594/7314/6233/5595/4194 14 Human_coronavirus_229E R-HSA-3371453 Regulation of HSF1-mediated heat shock response 21/947 69/10654 2.913730685974112e-7 2.0219037246317596e-6 1.0014625387674907e-6 3303/9972/2932/4928/472/57122/23411/8021/3313/10808/3309/6117/7266/3312/7531/6767/9531/9532/5594/3308/5595 21 Human_coronavirus_229E R-HSA-1433557 Signaling by SCF-KIT 16/947 43/10654 3.5477781900024737e-7 2.4349778178377633e-6 1.2060609205012723e-6 5295/7409/5777/867/3932/4318/4067/5290/3845/2534/3265/5781/6774/6772/6654/2885 16 Human_coronavirus_229E R-HSA-5696395 Formation of Incision Complex in GG-NER 16/947 43/10654 3.5477781900024737e-7 2.4349778178377633e-6 1.2060609205012723e-6 7311/7341/6613/10401/1642/6117/8450/54778/7316/9978/142/7329/7314/6233/8451/8554 16 Human_coronavirus_229E R-HSA-202403 TCR signaling 29/947 119/10654 3.703413477142704e-7 2.5279822430930633e-6 1.2521266390110631e-6 5295/8454/6500/1147/7311/5170/8945/23118/3932/5705/5788/5290/55824/5335/4790/6885/5682/7316/5728/4690/1445/7321/5702/5970/5714/7314/6233/3635/5717 29 Human_coronavirus_229E R-HSA-6807004 Negative regulation of MET activity 11/947 21/10654 3.957910244081882e-7 2.67739339143961e-6 1.326130987546773e-6 3082/7311/867/9146/7316/5771/2060/7314/30011/6233/2885 11 Human_coronavirus_229E R-HSA-9006335 Signaling by Erythropoietin 12/947 25/10654 3.964929703883499e-7 2.67739339143961e-6 1.326130987546773e-6 5295/7409/5293/4067/6464/5290/5335/3845/3265/5336/6654/2885 12 Human_coronavirus_229E R-HSA-9013694 Signaling by NOTCH4 23/947 82/10654 4.139577089598342e-7 2.780379050553753e-6 1.3771404784422293e-6 8454/6500/22938/8850/7311/1387/5705/4088/59/2033/5682/4855/7316/9978/2648/5702/4851/23462/207/5714/7314/6233/5717 23 Human_coronavirus_229E R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 14/947 34/10654 4.4663277788371915e-7 2.983887069265698e-6 1.4779393713845354e-6 7128/7311/9636/7706/5300/7323/7316/1540/7321/83737/3661/51191/7314/6233 14 Human_coronavirus_229E R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 8/947 11/10654 4.89985104797585e-7 3.239059429609299e-6 1.6043279608607907e-6 7311/23118/6885/7316/10454/7314/6233/257397 8 Human_coronavirus_229E R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 8/947 11/10654 4.89985104797585e-7 3.239059429609299e-6 1.6043279608607907e-6 7311/23118/6885/7316/10454/7314/6233/257397 8 Human_coronavirus_229E R-HSA-140877 Formation of Fibrin Clot (Clotting Cascade) 15/947 39/10654 4.996975957943071e-7 3.285969530458899e-6 1.6275628499004436e-6 2266/2157/2243/7450/2244/5196/3827/2153/2162/5624/5657/2147/5627/2/710 15 Human_coronavirus_229E R-HSA-140875 Common Pathway of Fibrin Clot Formation 11/947 22/10654 7.281254805772457e-7 4.763154185442816e-6 2.3592223630545626e-6 2266/2157/2243/2244/5196/2153/2162/5624/5657/2147/5627 11 Human_coronavirus_229E R-HSA-182971 EGFR downregulation 13/947 31/10654 9.000266617832159e-7 5.857168327459685e-6 2.901094939263052e-6 7311/867/1956/29924/9146/7316/1950/5782/2060/7314/30011/6233/2885 13 Human_coronavirus_229E R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 9/947 15/10654 1.0209225088883787e-6 6.60968387197837e-6 3.2738209590506337e-6 7311/867/9146/7316/2060/7314/30011/6233/2885 9 Human_coronavirus_229E R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 14/947 36/10654 1.0281918169481885e-6 6.622609856856024e-6 3.2802232864581884e-6 2266/10256/2243/7450/60/2244/71/2335/3845/3690/3265/1445/5594/5595 14 Human_coronavirus_229E R-HSA-187037 Signaling by NTRK1 (TRKA) 22/947 80/10654 1.0676323201680855e-6 6.84156221495467e-6 3.3886718647655135e-6 5295/5898/1432/4208/5518/9252/387/6464/5290/160/3667/5335/3845/5528/3265/5603/6774/4205/5594/6654/2885/5595 22 Human_coronavirus_229E R-HSA-1538133 G0 and Early G1 12/947 27/10654 1.1204252485558578e-6 7.1434218892698335e-6 3.538184995439551e-6 1017/5928/4149/1874/1875/7027/993/3065/1859/5933/5111/4609 12 Human_coronavirus_229E R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 28/947 119/10654 1.2576026858965062e-6 7.97752006811117e-6 3.951319443725865e-6 1387/10499/23054/57761/10001/8841/25942/196/2033/5468/9967/892/4802/9611/6721/51129/405/51586/8202/8648/9612/6256/1024/6667/23309/183/9862/2274 28 Human_coronavirus_229E R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 11/947 23/10654 1.283766685699636e-6 8.089093008637745e-6 4.0065822729675725e-6 7311/23118/5601/5602/6885/5599/7316/10454/7314/6233/257397 11 Human_coronavirus_229E R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 10/947 19/10654 1.2880721351333988e-6 8.089093008637745e-6 4.0065822729675725e-6 5928/4149/1874/1875/7027/993/3065/5933/5111/4609 10 Human_coronavirus_229E R-HSA-4641265 Repression of WNT target genes 8/947 12/10654 1.355051867303469e-6 8.467388782752025e-6 4.193954718912544e-6 51176/1487/3065/7088/83439/6934/1488/6932 8 Human_coronavirus_229E R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 16/947 47/10654 1.4298865026372763e-6 8.760670474694726e-6 4.339219117117485e-6 2266/818/10256/815/2243/7450/60/2244/71/2335/3845/3690/3265/1445/5594/5595 16 Human_coronavirus_229E R-HSA-6802949 Signaling by RAS mutants 16/947 47/10654 1.4298865026372763e-6 8.760670474694726e-6 4.339219117117485e-6 2266/818/10256/815/2243/7450/60/2244/71/2335/3845/3690/3265/1445/5594/5595 16 Human_coronavirus_229E R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 16/947 47/10654 1.4298865026372763e-6 8.760670474694726e-6 4.339219117117485e-6 2266/818/10256/815/2243/7450/60/2244/71/2335/3845/3690/3265/1445/5594/5595 16 Human_coronavirus_229E R-HSA-9649948 Signaling downstream of RAS mutants 16/947 47/10654 1.4298865026372763e-6 8.760670474694726e-6 4.339219117117485e-6 2266/818/10256/815/2243/7450/60/2244/71/2335/3845/3690/3265/1445/5594/5595 16 Human_coronavirus_229E R-HSA-9607240 FLT3 Signaling 48/947 267/10654 1.6065516454160338e-6 9.795285760400672e-6 4.8516710395548084e-006 5295/88/2266/3082/7311/818/5170/10256/815/5518/5155/57761/5921/5705/2243/7450/6464/1956/6711/60/2247/5290/2244/3667/71/2335/3845/2534/3690/5528/5682/7316/3265/9978/1950/5529/1445/5781/5702/10048/5714/5594/6654/7314/6233/2885/5595/5717 48 Human_coronavirus_229E R-HSA-2871837 FCERI mediated NF-kB activation 22/947 82/10654 1.6859004001709789e-6 1.02294246503128e-5 5.066702957035589e-6 8454/6500/1147/7311/5170/8945/23118/5705/4067/4790/6885/5682/7316/10454/7321/5702/5970/5714/7314/6233/5717/257397 22 Human_coronavirus_229E R-HSA-166520 Signaling by NTRKs 25/947 101/10654 1.721990736315365e-6 1.0398174830827396e-5 5.150286058514073e-6 5295/5898/1432/4208/5518/9252/387/6464/5290/160/3667/5335/3845/2534/5528/3265/5603/5781/6774/4205/5045/5594/6654/2885/5595 25 Human_coronavirus_229E R-HSA-2871809 FCERI mediated Ca+2 mobilization 13/947 33/10654 2.1129034486066293e-6 1.267428286492358e-5 6.277657704634459e-6 7409/3708/4067/3710/6464/5335/5336/6850/695/3709/6654/2885/7410 13 Human_coronavirus_229E R-HSA-2172127 DAP12 interactions 15/947 43/10654 2.1438214770019236e-6 1.267428286492358e-5 6.277657704634459e-6 5295/3932/6464/5290/5335/3845/2534/7305/3265/5336/6850/695/6654/2885/7410 15 Human_coronavirus_229E R-HSA-75893 TNF signaling 15/947 43/10654 2.1438214770019236e-6 1.267428286492358e-5 6.277657704634459e-6 7124/1147/7128/7311/23118/331/6885/7316/1540/10454/55072/7375/7314/6233/257397 15 Human_coronavirus_229E R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 9/947 16/10654 2.1493807724750976e-6 1.267428286492358e-5 6.277657704634459e-6 5295/5170/4067/6464/5290/2534/6850/6654/2885 9 Human_coronavirus_229E R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 9/947 16/10654 2.1493807724750976e-6 1.267428286492358e-5 6.277657704634459e-6 7311/23118/7099/6885/7316/10454/7314/6233/257397 9 Human_coronavirus_229E R-HSA-3214841 PKMTs methylate histone lysines 20/947 71/10654 2.1742413659924345e-6 1.2677874987949792e-5 6.279436907373723e-6 5931/84444/80854/9070/5928/11091/4790/55870/23512/55729/2146/5970/8085/29072/63976/6839/2122/79723/5929/9757 20 Human_coronavirus_229E R-HSA-450302 activated TAK1 mediates p38 MAPK activation 11/947 24/10654 2.180271494742958e-6 1.2677874987949792e-5 6.279436907373723e-6 7311/1432/23118/6885/5606/7316/10454/5608/7314/6233/257397 11 Human_coronavirus_229E R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 11/947 24/10654 2.180271494742958e-6 1.2677874987949792e-5 6.279436907373723e-6 7514/2353/1956/2309/595/1950/207/5594/6722/5595/1027 11 Human_coronavirus_229E R-HSA-5689896 Ovarian tumor domain proteases 14/947 38/10654 2.2109471057612225e-6 1.2797002602931315e-5 6.338441617777746e-6 7128/7311/387/7706/7316/5728/79155/80124/7321/7157/55611/2099/7314/6233 14 Human_coronavirus_229E R-HSA-9018519 Estrogen-dependent gene expression 32/947 150/10654 2.2543106105255034e-6 1.2988138196422166e-5 6.43311236514038e-6 3727/1025/2353/51523/8850/3725/1387/10499/3838/1386/2033/4435/904/8243/9126/595/3276/9687/865/8312/1655/3065/8202/5430/8648/23028/861/6667/2625/2099/4609/7528 32 Human_coronavirus_229E R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 10/947 20/10654 2.3712362140662534e-6 1.359941865236171e-5 6.735883693886834e-6 22938/8850/1387/4088/59/2033/4855/2648/4851/23462 10 Human_coronavirus_229E R-HSA-5684996 MAPK1/MAPK3 signaling 46/947 255/10654 2.4013290141325575e-6 1.3709405644320419e-5 6.790360992116466e-6 88/2266/3082/7311/818/10256/815/5518/5155/5921/5705/2243/7450/6464/1956/6711/60/2247/2244/3667/71/2335/3845/2534/3690/5528/5682/7316/3265/9978/1950/5529/1445/7297/5781/5702/3569/10048/5714/5594/6654/7314/6233/2885/5595/5717 46 Human_coronavirus_229E R-HSA-1169408 ISG15 antiviral mechanism 20/947 72/10654 2.762656453723271e-6 1.5700889166861666e-5 7.776756199811636e-6 7311/9972/9636/4928/3837/3838/57122/7706/5300/8021/9775/5335/7316/3661/4734/6772/51191/7314/6233/5595 20 Human_coronavirus_229E R-HSA-8863795 Downregulation of ERBB2 signaling 12/947 29/10654 2.828007772510963e-6 1.5999899830062025e-5 7.924858196083353e-6 7311/8065/1956/7316/26469/1950/5782/10273/207/11140/7314/6233 12 Human_coronavirus_229E R-HSA-983169 Class I MHC mediated antigen processing & presentation 60/947 371/10654 3.209686631986797e-6 1.8077876277019807e-5 8.95409393204719e-6 8454/6500/64219/57154/3685/1147/7311/23327/197131/8945/26270/5705/63893/6502/8065/7099/868/4615/9320/64750/3309/8881/29882/57520/7323/5682/54778/7316/9978/2923/23304/7317/7321/991/5702/7332/8453/11059/83737/55236/3105/10273/695/4734/51676/63891/10075/51132/10393/5714/3693/9817/7704/51191/7314/996/6233/5717/25831/821 60 Human_coronavirus_229E R-HSA-216083 Integrin cell surface interactions 22/947 85/10654 3.23796779767218e-6 1.815574800837615e-5 8.992664325301968e-6 2266/1281/3685/4060/8516/2243/1277/7450/999/1280/2244/7448/50848/2335/3690/3688/3694/3696/2200/7057/1278/3693 22 Human_coronavirus_229E R-HSA-202424 Downstream TCR signaling 24/947 98/10654 3.3857693587463524e-6 1.8900116953712972e-5 9.361355279621493e-6 5295/8454/6500/1147/7311/5170/8945/23118/3932/5705/5290/4790/6885/5682/7316/5728/7321/5702/5970/5714/7314/6233/3635/5717 24 Human_coronavirus_229E R-HSA-5654738 Signaling by FGFR2 20/947 73/10654 3.4919879143862582e-6 1.9406800090571416e-5 9.6123188514312e-6 5295/7311/867/5518/6464/2247/5290/5335/3845/4686/7316/3265/5781/5430/5594/6654/7314/6233/2885/5595 20 Human_coronavirus_229E R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 11/947 25/10654 3.581811763878733e-6 1.981830649969907e-5 9.816140748677631e-6 7311/9184/8881/29882/7316/7321/991/10393/7314/996/6233 11 Human_coronavirus_229E R-HSA-3700989 Transcriptional Regulation by TP53 59/947 365/10654 3.94294266276498e-6 2.1720771861547434e-5 1.0758444661560957e-5 2475/7249/672/5931/7295/1025/2353/1017/604/7311/834/1460/5170/5928/1432/3725/1387/8812/5518/472/1386/57459/1616/5325/5300/28984/6117/6794/2033/1874/904/3622/7316/5728/3276/7531/905/1029/7027/51497/28996/7874/3065/3066/5608/5430/7157/1026/207/8626/10971/5933/5371/5111/7314/10542/6233/1027/4194 59 Human_coronavirus_229E R-HSA-5218921 VEGFR2 mediated cell proliferation 10/947 21/10654 4.167095477391763e-6 2.2755964867843712e-5 1.1271182732899458e-5 5170/3708/5921/5590/3710/5335/3845/3265/3709/7422 10 Human_coronavirus_229E R-HSA-5621575 CD209 (DC-SIGN) signaling 10/947 21/10654 4.167095477391763e-6 2.2755964867843712e-5 1.1271182732899458e-5 5971/1387/4067/9252/4790/3845/2534/2033/3265/5970 10 Human_coronavirus_229E R-HSA-9034015 Signaling by NTRK3 (TRKC) 9/947 17/10654 4.207294883546937e-6 2.2777424024719625e-5 1.1281811597895827e-5 5295/6464/5290/3667/5335/3845/3265/6654/2885 9 Human_coronavirus_229E R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 9/947 17/10654 4.207294883546937e-6 2.2777424024719625e-5 1.1281811597895827e-5 7311/23118/7099/6885/7316/10454/7314/6233/257397 9 Human_coronavirus_229E R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 21/947 80/10654 4.230870259651803e-6 2.2806751270912723e-5 1.1296337580547619e-5 7311/9972/9636/4928/3837/3838/57122/7706/5300/8021/9775/5335/7316/3661/2316/4734/6772/51191/7314/6233/5595 21 Human_coronavirus_229E R-HSA-6804758 Regulation of TP53 Activity through Acetylation 12/947 30/10654 4.334267383524777e-6 2.3264272793620168e-5 1.152295107360838e-5 5931/5928/57459/5300/2033/3622/3065/3066/5608/7157/207/5371 12 Human_coronavirus_229E R-HSA-5674135 MAP2K and MAPK activation 14/947 40/10654 4.480352522781189e-6 2.3946054334524138e-5 1.186064206478693e-5 2266/10256/2243/7450/60/2244/71/2335/3845/3690/3265/1445/5594/5595 14 Human_coronavirus_229E R-HSA-109581 Apoptosis 35/947 178/10654 5.462744463933735e-6 2.9072911214833774e-5 1.440000882330436e-5 6093/7311/3837/5705/7099/999/331/100506658/2339/5599/7431/5682/8837/7316/1499/4976/10018/4137/7531/1029/7027/5702/6774/7157/207/8626/10971/5339/4836/5714/5594/7314/6233/5595/5717 35 Human_coronavirus_229E R-HSA-1234174 Cellular response to hypoxia 20/947 75/10654 5.495839992172366e-6 2.9125633038685622e-5 1.4426122297907477e-5 7311/3091/10370/1387/5705/2034/2033/7323/5682/7316/9978/7321/405/5702/8453/7422/5714/7314/6233/5717 20 Human_coronavirus_229E R-HSA-162909 Host Interactions of HIV factors 28/947 129/10654 6.765223634410078e-6 3.570218859167672e-5 1.768353457733904e-5 6500/7514/1025/7311/5905/9972/8945/4928/3932/3837/57122/5705/8065/160/8021/2534/904/5682/7316/9978/293/5702/5901/292/5714/7314/6233/5717 28 Human_coronavirus_229E R-HSA-9613829 Chaperone Mediated Autophagy 10/947 22/10654 7.032903808070513e-6 3.695952796207768e-5 1.8306303239681453e-5 7311/10226/10013/5116/7431/7316/3312/1915/7314/6233 10 Human_coronavirus_229E R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 9/947 18/10654 7.751684512785129e-6 4.0567148950242175e-5 2.0093182223929873e-5 3665/7311/7099/7316/5781/3661/7314/6233/10010 9 Human_coronavirus_229E R-HSA-69275 G2/M Transition 37/947 196/10654 7.967636879848654e-6 4.152428183024858e-5 2.0567256588733586e-5 8454/6500/7514/1017/7311/5928/7277/8945/5518/10381/5705/5116/2305/2033/9662/5682/7316/10376/728642/9978/1453/7531/993/7465/5702/203068/5520/7157/1026/55755/5714/5500/7314/347688/6233/1778/5717 37 Human_coronavirus_229E R-HSA-5357801 Programmed Cell Death 35/947 181/10654 8.050198322433728e-6 4.1781194599077526e-5 2.0694507214259826e-5 6093/7311/3837/5705/7099/999/331/100506658/2339/5599/7431/5682/8837/7316/1499/4976/10018/4137/7531/1029/7027/5702/6774/7157/207/8626/10971/5339/4836/5714/5594/7314/6233/5595/5717 35 Human_coronavirus_229E R-HSA-1989781 PPARA activates gene expression 26/947 117/10654 9.151398665993471e-6 4.730105647937366e-5 2.3428531997410185e-5 1387/10499/23054/57761/10001/8841/196/2033/5468/9967/892/4802/9611/6721/51129/405/51586/8202/8648/9612/6256/1024/6667/183/9862/2274 26 Human_coronavirus_229E R-HSA-5633007 Regulation of TP53 Activity 32/947 160/10654 9.47963920229837e-6 4.879683130363423e-5 2.4169399346670995e-5 2475/672/5931/1017/7311/1460/5170/5928/1432/5518/472/57459/1616/5300/6117/6794/2033/3622/7316/1029/28996/7874/3065/3066/5608/7157/207/8626/5371/7314/6233/4194 32 Human_coronavirus_229E R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 21/947 84/10654 9.717226160601413e-6 4.98156573784301e-5 2.467403076655396e-5 7311/7341/6613/10401/60/8607/1642/6117/8450/54778/7316/9978/142/10987/7329/5111/7314/6233/8451/8554/7528 21 Human_coronavirus_229E R-HSA-453274 Mitotic G2-G2/M phases 37/947 198/10654 1.013722132728345e-5 5.17575202726342e-5 2.5635848542680867e-5 8454/6500/7514/1017/7311/5928/7277/8945/5518/10381/5705/5116/2305/2033/9662/5682/7316/10376/728642/9978/1453/7531/993/7465/5702/203068/5520/7157/1026/55755/5714/5500/7314/347688/6233/1778/5717 37 Human_coronavirus_229E R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 7/947 11/10654 1.0284565480701988e-5 5.187716563759717e-5 2.56951096981394e-5 3091/10370/1387/2034/2033/405/7422 7 Human_coronavirus_229E R-HSA-5655291 Signaling by FGFR4 in disease 7/947 11/10654 1.0284565480701988e-5 5.187716563759717e-5 2.56951096981394e-5 5295/5290/5335/3845/3265/6654/2885 7 Human_coronavirus_229E R-HSA-8851805 MET activates RAS signaling 7/947 11/10654 1.0284565480701988e-5 5.187716563759717e-5 2.56951096981394e-5 3082/6464/3845/3265/10048/6654/2885 7 Human_coronavirus_229E R-HSA-5696398 Nucleotide Excision Repair 25/947 111/10654 1.0561414404078907e-5 5.306054596609243e-5 2.6281245948676354e-5 10450/7311/7341/6613/10401/60/8607/1642/6117/2033/8450/54778/7316/9978/142/7874/10987/5430/7329/5111/7314/6233/8451/8554/7528 25 Human_coronavirus_229E R-HSA-2559580 Oxidative Stress Induced Senescence 27/947 125/10654 1.0816310367750515e-5 5.412464470874362e-5 2.6808301226003584e-5 1912/5931/7295/2353/1030/7311/5928/1432/3725/1019/5601/5602/5599/23512/5606/7316/1029/7027/2146/5608/7157/23135/5594/7314/6233/5595/4194 27 Human_coronavirus_229E R-HSA-74751 Insulin receptor signalling cascade 16/947 54/10654 1.1058877590533011e-5 5.511885021313278e-5 2.7300737911466204e-5 5295/5170/3643/57761/6464/2247/5290/3667/3845/3265/5781/3630/5594/6654/2885/5595 16 Human_coronavirus_229E R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 10/947 23/10654 1.1455316979125051e-5 5.672614598983654e-5 2.8096842339920712e-5 7311/8881/29882/7316/7321/991/10393/7314/996/6233 10 Human_coronavirus_229E R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 17/947 60/10654 1.1471688759091147e-5 5.672614598983654e-5 2.8096842339920712e-5 8454/6500/1017/7311/5705/1019/6502/5682/7316/595/5702/1026/5714/7314/6233/5717/1027 17 Human_coronavirus_229E R-HSA-5696394 DNA Damage Recognition in GG-NER 13/947 38/10654 1.3103141845346778e-5 6.453939669708061e-5 3.196679806233207e-5 7311/60/8607/1642/8450/7316/9978/142/10987/7314/6233/8451/7528 13 Human_coronavirus_229E R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 35/947 185/10654 1.3255685568619263e-5 6.503570732103826e-5 3.2212624058610136e-5 6158/7311/6204/6202/9349/6188/6189/6232/6206/6194/6134/6169/6191/6135/55781/117246/6147/6175/1453/6129/6124/6207/6208/6222/6157/6137/6152/6136/6193/6122/6133/6210/6205/6233/27043 35 Human_coronavirus_229E R-HSA-354194 GRB2:SOS provides linkage to MAPK signaling for Integrins 8/947 15/10654 1.3806510864904471e-5 6.73278880286818e-5 3.334795660823914e-5 2266/2243/7450/2244/2335/3690/6654/2885 8 Human_coronavirus_229E R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 12/947 33/10654 1.3830091649203747e-5 6.73278880286818e-5 3.334795660823914e-5 1147/7311/23118/351/4790/6885/7316/10454/5970/7314/6233/257397 12 Human_coronavirus_229E R-HSA-8941858 Regulation of RUNX3 expression and activity 16/947 55/10654 1.4325185346934804e-5 6.893528283891226e-5 3.414411008866673e-5 57154/7311/5705/7040/64750/2033/5682/7316/1029/865/864/5702/5714/7314/6233/5717 16 Human_coronavirus_229E R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 21/947 86/10654 1.4379812184550167e-5 6.893528283891226e-5 3.414411008866673e-5 8454/6500/1017/7311/9184/8945/5705/6502/8881/29882/5682/7316/7321/991/5702/10393/5714/7314/996/6233/5717 21 Human_coronavirus_229E R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 21/947 86/10654 1.4379812184550167e-5 6.893528283891226e-5 3.414411008866673e-5 5295/7409/26999/3708/4067/3710/60/5290/5335/71/2534/4690/5336/6850/695/3709/4771/5594/2885/5595/7410 21 Human_coronavirus_229E R-HSA-453276 Regulation of mitotic cell cycle 21/947 86/10654 1.4379812184550167e-5 6.893528283891226e-5 3.414411008866673e-5 8454/6500/1017/7311/9184/8945/5705/6502/8881/29882/5682/7316/7321/991/5702/10393/5714/7314/996/6233/5717 21 Human_coronavirus_229E R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 20/947 80/10654 1.5753655452800237e-5 7.523418725747947e-5 3.726399989035398e-5 8454/6500/1017/7311/9184/8945/5705/8881/29882/5682/7316/7321/991/5702/10393/5714/7314/996/6233/5717 20 Human_coronavirus_229E R-HSA-5673001 RAF/MAP kinase cascade 43/947 249/10654 1.5842128352363868e-5 7.537012579760992e-5 3.733133116525935e-5 88/2266/3082/7311/818/10256/815/5518/5155/5921/5705/2243/7450/6464/1956/6711/60/2247/2244/3667/71/2335/3845/2534/3690/5528/5682/7316/3265/9978/1950/5529/1445/5702/10048/5714/5594/6654/7314/6233/2885/5595/5717 43 Human_coronavirus_229E R-HSA-5654732 Negative regulation of FGFR3 signaling 11/947 29/10654 1.992630730992742e-5 9.408812774913097e-5 4.660248365717097e-5 7311/867/5518/2247/7316/5781/5594/7314/6233/2885/5595 11 Human_coronavirus_229E R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 11/947 29/10654 1.992630730992742e-5 9.408812774913097e-5 4.660248365717097e-5 4089/2308/4088/2908/25942/2309/3630/3065/3066/4087/4303 11 Human_coronavirus_229E R-HSA-8957275 Post-translational protein phosphorylation 24/947 108/10654 2.003753896872638e-5 9.425898481168664e-5 4.668711031152096e-5 2266/7076/2243/197/351/6383/57104/3912/5265/3827/338/7018/2335/2153/4052/213/2200/5624/2621/3569/3915/5768/652/4221 24 Human_coronavirus_229E R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 50/947 309/10654 2.0913637478939507e-5 9.801316669234336e-5 4.8546581893374894e-5 8454/6500/64219/57154/7311/23327/197131/8945/26270/5705/63893/6502/8065/868/9320/64750/8881/29882/57520/7323/5682/54778/7316/9978/23304/7317/7321/991/5702/7332/8453/11059/83737/55236/10273/4734/51676/63891/10075/51132/10393/5714/9817/7704/51191/7314/996/6233/5717/25831 50 Human_coronavirus_229E R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 7/947 12/10654 2.278588453945993e-5 1.0639059844446717e-4 5.269598028887036e-5 3665/7311/7316/3661/7314/6233/10010 7 Human_coronavirus_229E R-HSA-193639 p75NTR signals via NF-kB 8/947 16/10654 2.5463640957333792e-5 1.1845308534226387e-4 5.8670611328593656e-5 7311/4615/4790/7316/5970/8878/7314/6233 8 Human_coronavirus_229E R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 24/947 110/10654 2.7662280447662113e-5 1.267644499755944e-4 6.278728623497846e-5 2353/1017/1030/7311/3725/1051/1019/8881/4790/29882/7316/1029/7321/6774/3569/5970/1026/10393/5594/7314/996/6233/5595/1027 24 Human_coronavirus_229E R-HSA-5654708 Downstream signaling of activated FGFR3 10/947 25/10654 2.7746041270696426e-5 1.267644499755944e-4 6.278728623497846e-5 5295/6464/2247/5290/5335/3845/3265/5781/6654/2885 10 Human_coronavirus_229E R-HSA-9006115 Signaling by NTRK2 (TRKB) 10/947 25/10654 2.7746041270696426e-5 1.267644499755944e-4 6.278728623497846e-5 5295/6464/5290/5335/3845/2534/3265/5781/6654/2885 10 Human_coronavirus_229E R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 10/947 25/10654 2.7746041270696426e-5 1.267644499755944e-4 6.278728623497846e-5 22938/8850/5087/1387/26508/2033/2648/4851/23462/6772 10 Human_coronavirus_229E R-HSA-913531 Interferon Signaling 36/947 199/10654 2.7754955209624572e-5 1.267644499755944e-4 6.278728623497846e-5 3665/7311/818/23650/9972/5777/7341/9636/4928/815/3837/3838/57122/55223/7706/5300/8021/9775/5335/3662/7316/5771/3458/7297/5781/3105/3661/2316/4734/5371/6772/51191/7314/6233/5595/8554 36 Human_coronavirus_229E R-HSA-69052 Switching of origins to a post-replicative state 21/947 90/10654 3.0150395298525264e-5 1.3720614672082512e-4 6.795912899095512e-5 8454/6500/1017/7311/4173/5705/6502/8881/29882/5682/7316/9978/7321/5702/10393/5714/4176/7314/996/6233/5717 21 Human_coronavirus_229E R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 19/947 77/10654 3.114749661384743e-5 1.412319702057486e-4 6.995314648977325e-5 672/1912/9972/7341/4928/9063/6613/57122/8021/6117/8243/9126/142/1029/6996/7329/5371/51588/8554 19 Human_coronavirus_229E R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 11/947 31/10654 4.130078674216858e-5 1.8592755608660836e-4 9.20911713436017e-5 2932/7471/5518/1455/857/5528/1499/8312/5529/1855/4041 11 Human_coronavirus_229E R-HSA-5654733 Negative regulation of FGFR4 signaling 11/947 31/10654 4.130078674216858e-5 1.8592755608660836e-4 9.20911713436017e-5 7311/867/5518/2247/7316/5781/5594/7314/6233/2885/5595 11 Human_coronavirus_229E R-HSA-8868773 rRNA processing in the nucleus and cytosol 35/947 195/10654 4.235113054557175e-5 1.8997507130442186e-4 9.40959329038831e-5 6158/7311/6204/6202/9349/6188/6189/6232/6206/6194/6134/6169/6191/6135/55781/117246/6147/6175/1453/6129/6124/6207/6208/6222/6157/6137/6152/6136/6193/6122/6133/6210/6205/6233/27043 35 Human_coronavirus_229E R-HSA-186712 Regulation of beta-cell development 13/947 42/10654 4.41299429810455e-5 1.9724985190104323e-4 9.769918075219289e-5 6927/22938/2308/8850/1387/2033/5080/2648/3172/3630/4851/207/6928 13 Human_coronavirus_229E R-HSA-180292 GAB1 signalosome 8/947 17/10654 4.4358170800700004e-5 1.9756688838893334e-4 9.785621106089475e-5 5295/1956/5290/55824/1950/1445/5781/2885 8 Human_coronavirus_229E R-HSA-209560 NF-kB is activated and signals survival 7/947 13/10654 4.5580058098578344e-5 2.0157941187258594e-4 9.984364097946554e-5 7311/4790/7316/5970/8878/7314/6233 7 Human_coronavirus_229E R-HSA-2892247 POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation 7/947 13/10654 4.5580058098578344e-5 2.0157941187258594e-4 9.984364097946554e-5 6997/79923/6657/2247/5460/6774/57167 7 Human_coronavirus_229E R-HSA-72312 rRNA processing 36/947 205/10654 5.332980740655521e-5 2.350253968513451e-4 1.1640966270461359e-4 60528/6158/7311/6204/6202/9349/6188/6189/6232/6206/6194/6134/6169/6191/6135/55781/117246/6147/6175/1453/6129/6124/6207/6208/6222/6157/6137/6152/6136/6193/6122/6133/6210/6205/6233/27043 36 Human_coronavirus_229E R-HSA-6802952 Signaling by BRAF and RAF fusions 17/947 67/10654 5.504332721430301e-5 2.4172873769637965e-4 1.197298725934968e-4 2266/818/10256/815/2243/7450/60/2244/71/2335/3845/3690/3265/10018/1445/5594/5595 17 Human_coronavirus_229E R-HSA-5617472 Activation of anterior HOX genes in hindbrain development during early embryogenesis 25/947 122/10654 5.768117355460206e-5 2.515540068909034e-4 1.2459639463000664e-4 5931/9070/5928/5087/5915/3725/22976/1387/23054/9063/8841/11091/7403/2033/23512/5080/9611/10664/2146/8202/5430/8085/6256/7528/5929 25 Human_coronavirus_229E R-HSA-5619507 Activation of HOX genes during differentiation 25/947 122/10654 5.768117355460206e-5 2.515540068909034e-4 1.2459639463000664e-4 5931/9070/5928/5087/5915/3725/22976/1387/23054/9063/8841/11091/7403/2033/23512/5080/9611/10664/2146/8202/5430/8085/6256/7528/5929 25 Human_coronavirus_229E R-HSA-190236 Signaling by FGFR 20/947 87/10654 5.812071827466469e-5 2.5259384828020363e-4 1.2511143507676865e-4 5295/7311/867/5518/6464/2247/5290/5335/3845/4686/7316/3265/5781/5430/5594/6654/7314/6233/2885/5595 20 Human_coronavirus_229E R-HSA-5654716 Downstream signaling of activated FGFR4 10/947 27/10654 6.072236045859939e-5 2.629906370206925e-4 1.3026103459539833e-4 5295/6464/2247/5290/5335/3845/3265/5781/6654/2885 10 Human_coronavirus_229E R-HSA-69615 G1/S DNA Damage Checkpoints 17/947 68/10654 6.741092242520368e-5 2.9095573390397185e-4 1.4411233551562804e-4 1017/7311/472/5705/5682/7316/1029/993/5702/7157/1026/5714/7314/6233/5717/1027/4194 17 Human_coronavirus_229E R-HSA-5655302 Signaling by FGFR1 in disease 12/947 38/10654 6.949791696228127e-5 2.9791598534001796e-4 1.4755979495134985e-4 5295/2247/5290/5335/3845/3265/6774/7750/6772/6654/2885/613 12 Human_coronavirus_229E R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 12/947 38/10654 6.949791696228127e-5 2.9791598534001796e-4 1.4755979495134985e-4 1912/1460/6599/8289/10138/2033/6597/6601/865/28996/861/57492 12 Human_coronavirus_229E R-HSA-210993 Tie2 Signaling 8/947 18/10654 7.364335983103167e-5 3.144714790746489e-4 1.5575984255205959e-4 5295/6464/5290/3845/3265/5781/6654/2885 8 Human_coronavirus_229E R-HSA-3858494 Beta-catenin independent WNT signaling 28/947 146/10654 7.386073752151387e-5 3.144714790746489e-4 1.5575984255205959e-4 50855/57154/7311/51176/815/7471/3708/5705/387/3710/160/64750/3845/6885/5682/7316/1499/51701/5702/3709/83439/5714/6934/7314/6233/1855/5717/6932 28 Human_coronavirus_229E R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 18/947 75/10654 7.414519388048114e-5 3.1461609295231185e-4 1.5583147078010082e-4 5295/7409/3082/930/3932/5293/5155/1956/2247/5290/118788/3667/2534/391/1950/5781/2099/2885 18 Human_coronavirus_229E R-HSA-8853334 Signaling by FGFR3 fusions in cancer 6/947 10/10654 7.455446150155048e-5 3.152875543634593e-4 1.5616405014147203e-4 5295/5290/3845/3265/6654/2885 6 Human_coronavirus_229E R-HSA-162906 HIV Infection 39/947 233/10654 7.90907847882407e-5 3.325822285373308e-4 1.647302187944708e-4 6500/7514/1025/7311/23327/5905/51652/9972/8945/4928/3932/3837/8812/57122/5705/8065/160/8021/2534/904/5682/4686/7316/9978/293/905/51497/2547/5702/5430/5901/292/4836/9397/5714/5045/7314/6233/5717 39 Human_coronavirus_229E R-HSA-72766 Translation 46/947 291/10654 7.963688322844709e-5 3.325822285373308e-4 1.647302187944708e-4 6158/7458/7311/6204/3646/6184/26986/8663/6202/51386/9349/6188/6189/6232/6206/6194/6134/6169/6191/8665/6135/23438/1938/6147/6175/6129/1915/6124/9669/1933/6207/6208/6222/6157/6137/7284/6152/6136/1964/6193/6122/6133/6210/6205/6233/1975 46 Human_coronavirus_229E R-HSA-389356 CD28 co-stimulation 11/947 33/10654 7.99680199190079e-5 3.325822285373308e-4 1.647302187944708e-4 2475/5295/7409/5170/3932/57761/4067/5290/2534/207/2885 11 Human_coronavirus_229E R-HSA-5357905 Regulation of TNFR1 signaling 11/947 33/10654 7.99680199190079e-5 3.325822285373308e-4 1.647302187944708e-4 7124/1147/7128/7311/331/7316/1540/55072/7375/7314/6233 11 Human_coronavirus_229E R-HSA-5654726 Negative regulation of FGFR1 signaling 11/947 33/10654 7.99680199190079e-5 3.325822285373308e-4 1.647302187944708e-4 7311/867/5518/2247/7316/5781/5594/7314/6233/2885/5595 11 Human_coronavirus_229E R-HSA-68882 Mitotic Anaphase 35/947 201/10654 8.055166458796552e-5 3.339039297771772e-4 1.6538486632443155e-4 7514/7311/9184/5905/7277/4928/5518/10381/57122/5705/6232/8881/29882/5528/5682/8243/9126/7316/10376/5501/5529/7321/991/5702/5520/2010/10393/5714/7314/347688/23592/996/6233/1778/5717 35 Human_coronavirus_229E R-HSA-180336 SHC1 events in EGFR signaling 7/947 14/10654 8.417258578879424e-5 3.4324924594391417e-4 1.7001366439226728e-4 6464/1956/3845/3265/1950/6654/2885 7 Human_coronavirus_229E R-HSA-198323 AKT phosphorylates targets in the cytosol 7/947 14/10654 8.417258578879424e-5 3.4324924594391417e-4 1.7001366439226728e-4 7249/1147/2932/2931/1026/207/1027 7 Human_coronavirus_229E R-HSA-877312 Regulation of IFNG signaling 7/947 14/10654 8.417258578879424e-5 3.4324924594391417e-4 1.7001366439226728e-4 5777/7341/5771/3458/5781/6772/8554 7 Human_coronavirus_229E R-HSA-8941856 RUNX3 regulates NOTCH signaling 7/947 14/10654 8.417258578879424e-5 3.4324924594391417e-4 1.7001366439226728e-4 22938/8850/1387/2033/2648/864/4851 7 Human_coronavirus_229E R-HSA-9027284 Erythropoietin activates RAS 7/947 14/10654 8.417258578879424e-5 3.4324924594391417e-4 1.7001366439226728e-4 7409/4067/6464/3845/3265/6654/2885 7 Human_coronavirus_229E R-HSA-2555396 Mitotic Metaphase and Anaphase 35/947 202/10654 8.933199213266074e-5 3.6262136743687144e-4 1.7960880670062938e-4 7514/7311/9184/5905/7277/4928/5518/10381/57122/5705/6232/8881/29882/5528/5682/8243/9126/7316/10376/5501/5529/7321/991/5702/5520/2010/10393/5714/7314/347688/23592/996/6233/1778/5717 35 Human_coronavirus_229E R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 16/947 63/10654 8.950049673999215e-5 3.6262136743687144e-4 1.7960880670062938e-4 1147/3665/7311/1387/6778/4615/4790/5591/2033/7316/1499/2547/5970/3661/7314/6233 16 Human_coronavirus_229E R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 19/947 83/10654 9.393437107794357e-5 3.793619616524023e-4 1.8790053581676985e-4 8454/6500/1147/7311/8945/5705/4790/3845/6885/5682/7316/3265/5702/2280/5970/5714/7314/6233/5717 19 Human_coronavirus_229E R-HSA-193704 p75 NTR receptor-mediated signalling 21/947 97/10654 9.722807500987583e-5 3.9140532760385913e-4 1.9386569612293055e-4 7409/7311/26574/387/8841/23370/4615/4790/5599/7316/10018/7531/11108/3065/3066/5970/8878/6654/7314/6233/7410 21 Human_coronavirus_229E R-HSA-388841 Costimulation by the CD28 family 17/947 70/10654 9.968135697370003e-5 3.999993110510135e-4 1.981223540321396e-4 2475/5295/7409/5170/5777/3932/5518/57761/4067/5290/2534/5528/5529/1445/5781/207/2885 17 Human_coronavirus_229E R-HSA-4791275 Signaling by WNT in cancer 11/947 34/10654 1.0881163240216716e-4 4.338647945940379e-4 2.1489615622282638e-4 2932/5518/22943/1487/5528/1499/8312/5529/6934/1488/4041 11 Human_coronavirus_229E R-HSA-5654727 Negative regulation of FGFR2 signaling 11/947 34/10654 1.0881163240216716e-4 4.338647945940379e-4 2.1489615622282638e-4 7311/867/5518/2247/7316/5781/5594/7314/6233/2885/5595 11 Human_coronavirus_229E R-HSA-6804760 Regulation of TP53 Activity through Methylation 8/947 19/10654 1.1733385014256608e-4 4.6636492335146515e-4 2.3099368898819639e-4 7311/472/2033/7316/7157/7314/6233/4194 8 Human_coronavirus_229E R-HSA-6802957 Oncogenic MAPK signaling 17/947 71/10654 1.2039481360295397e-4 4.770217220356788e-4 2.3627207318394753e-4 2266/818/10256/815/2243/7450/60/2244/71/2335/3845/3690/3265/10018/1445/5594/5595 17 Human_coronavirus_229E R-HSA-383280 Nuclear Receptor transcription pathway 14/947 52/10654 1.2416639122963898e-4 4.904181993220961e-4 2.4290743865182601e-4 367/5915/5467/2908/3164/7182/5468/3172/9611/8431/9612/7421/6256/2099 14 Human_coronavirus_229E R-HSA-982772 Growth hormone receptor signaling 9/947 24/10654 1.2761798684855476e-4 5.024708196921153e-4 2.4887718273385864e-4 1154/5777/4067/3667/6774/6772/5594/1442/5595 9 Human_coronavirus_229E R-HSA-2032785 YAP1- and WWTR1 (TAZ)-stimulated gene expression 7/947 15/10654 1.4574290134719786e-4 5.720408877877516e-4 2.833357062374801e-4 8850/25937/860/2626/1482/28996/10413 7 Human_coronavirus_229E R-HSA-1500931 Cell-Cell communication 25/947 129/10654 1.4851446209563585e-4 5.811033158632979e-4 2.8782438792759727e-4 5295/88/50855/56288/5777/6711/999/60/5290/81/50848/71/2534/3688/7305/1499/1500/4690/87/5781/667/2316/3691/5339/2885 25 Human_coronavirus_229E R-HSA-1059683 Interleukin-6 signaling 6/947 11/10654 1.5167833672656884e-4 5.916397233806536e-4 2.9304314156718597e-4 867/7297/5781/6774/3569/6772 6 Human_coronavirus_229E R-HSA-109606 Intrinsic Pathway for Apoptosis 14/947 53/10654 1.551378678196473e-4 6.013986480909784e-4 2.978768027336308e-4 331/5599/10018/7531/1029/7027/6774/7157/207/8626/10971/4836/5594/5595 14 Human_coronavirus_229E R-HSA-2428924 IGF1R signaling cascade 14/947 53/10654 1.551378678196473e-4 6.013986480909784e-4 2.978768027336308e-4 5295/5170/3479/57761/6464/2247/5290/3667/3845/3265/5781/3481/6654/2885 14 Human_coronavirus_229E R-HSA-69563 p53-Dependent G1 DNA Damage Response 16/947 66/10654 1.6209756604252653e-4 6.24523137881636e-4 3.093305183439883e-4 1017/7311/472/5705/5682/7316/1029/5702/7157/1026/5714/7314/6233/5717/1027/4194 16 Human_coronavirus_229E R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 16/947 66/10654 1.6209756604252653e-4 6.24523137881636e-4 3.093305183439883e-4 1017/7311/472/5705/5682/7316/1029/5702/7157/1026/5714/7314/6233/5717/1027/4194 16 Human_coronavirus_229E R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 10/947 30/10654 1.68953208497185e-4 6.430461511286799e-4 3.1850509161670285e-4 7311/1642/6117/8450/7316/9978/5111/7314/6233/8451 10 Human_coronavirus_229E R-HSA-5654696 Downstream signaling of activated FGFR2 10/947 30/10654 1.68953208497185e-4 6.430461511286799e-4 3.1850509161670285e-4 5295/6464/2247/5290/5335/3845/3265/5781/6654/2885 10 Human_coronavirus_229E R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 10/947 30/10654 1.68953208497185e-4 6.430461511286799e-4 3.1850509161670285e-4 7311/8239/7316/7874/7317/7321/7332/55236/7314/6233 10 Human_coronavirus_229E R-HSA-8874081 MET activates PTK2 signaling 10/947 30/10654 1.68953208497185e-4 6.430461511286799e-4 3.1850509161670285e-4 1281/3082/1277/1280/3912/2335/3688/1278/3911/3915 10 Human_coronavirus_229E R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 15/947 60/10654 1.7855734089583148e-4 6.755060848348324e-4 3.3458271550233483e-4 8454/6500/1147/7311/5971/8945/5705/5682/7316/5702/5970/5714/7314/6233/5717 15 Human_coronavirus_229E R-HSA-5610780 Degradation of GLI1 by the proteasome 15/947 60/10654 1.7855734089583148e-4 6.755060848348324e-4 3.3458271550233483e-4 8454/6500/7311/8945/5705/2735/5682/7316/9978/5702/83737/5714/7314/6233/5717 15 Human_coronavirus_229E R-HSA-167044 Signalling to RAS 8/947 20/10654 1.8040262374507433e-4 6.804375237952353e-4 3.3702529044836075e-4 5898/1432/6464/3845/3265/5603/6654/2885 8 Human_coronavirus_229E R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 14/947 54/10654 1.925633665712414e-4 7.219689206372514e-4 3.57596071150365e-4 5295/5170/3479/57761/6464/2247/5290/3667/3845/3265/5781/3481/6654/2885 14 Human_coronavirus_229E R-HSA-9604323 Negative regulation of NOTCH4 signaling 14/947 54/10654 1.925633665712414e-4 7.219689206372514e-4 3.57596071150365e-4 8454/6500/7311/5705/5682/4855/7316/9978/5702/207/5714/7314/6233/5717 14 Human_coronavirus_229E R-HSA-1169091 Activation of NF-kappaB in B cells 16/947 67/10654 1.9568320959647949e-4 7.314824739677924e-4 3.6230819821904566e-4 8454/6500/1147/7311/8945/5705/4790/6885/5682/7316/5702/5970/5714/7314/6233/5717 16 Human_coronavirus_229E R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 19/947 88/10654 2.1380113052093554e-4 7.968374478762464e-4 3.9467895716967954e-4 3315/7514/7311/3303/1432/26986/5705/8021/55802/5682/7316/3312/5702/207/5714/7314/6233/1994/5717 19 Human_coronavirus_229E R-HSA-5654687 Downstream signaling of activated FGFR1 10/947 31/10654 2.2974007599957507e-4 8.53708684779486e-4 4.2284766401665797e-4 5295/6464/2247/5290/5335/3845/3265/5781/6654/2885 10 Human_coronavirus_229E R-HSA-1433559 Regulation of KIT signaling 7/947 16/10654 2.3929343720598034e-4 8.839781092079745e-4 4.378403138970105e-4 5777/867/3932/4067/2534/6654/2885 7 Human_coronavirus_229E R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 7/947 16/10654 2.3929343720598034e-4 8.839781092079745e-4 4.378403138970105e-4 22938/8850/1387/2033/2648/4851/6928 7 Human_coronavirus_229E R-HSA-8986944 Transcriptional Regulation by MECP2 15/947 62/10654 2.639130158751023e-4 9.720667094989104e-4 4.8147119117822334e-4 818/4208/815/8841/6657/25942/2290/5728/5468/9611/28996/3065/3066/9612/5775 15 Human_coronavirus_229E R-HSA-389513 CTLA4 inhibitory signaling 8/947 21/10654 2.688636934744362e-4 9.845271107985186e-4 4.8764291190238384e-4 3932/5518/4067/2534/5528/5529/5781/207 8 Human_coronavirus_229E R-HSA-445144 Signal transduction by L1 8/947 21/10654 2.688636934744362e-4 9.845271107985186e-4 4.8764291190238384e-4 3685/1460/1956/3690/3688/5594/5595/7410 8 Human_coronavirus_229E R-HSA-8866907 Activation of the TFAP2 (AP-2) family of transcription factors 6/947 12/10654 2.805707889136779e-4 0.0010183257597900302 5.043836104893629e-4 10370/51741/1387/2033/4435/7021 6 Human_coronavirus_229E R-HSA-373760 L1CAM interactions 23/947 119/10654 2.8079229713746164e-4 0.0010183257597900302 5.043836104893629e-4 3685/1460/7277/10381/9252/24137/1956/6711/60/160/3912/71/3690/3688/10376/3312/10048/288/3915/5594/347688/5595/7410 23 Human_coronavirus_229E R-HSA-69239 Synthesis of DNA 23/947 119/10654 2.8079229713746164e-4 0.0010183257597900302 5.043836104893629e-4 8454/6500/1017/7311/4173/5705/6502/6117/8881/29882/5682/7316/9978/7321/5702/10393/5714/5111/4176/7314/996/6233/5717 23 Human_coronavirus_229E R-HSA-8948751 Regulation of PTEN stability and activity 16/947 69/10654 2.8133681420950676e-4 0.0010183257597900302 5.043836104893629e-4 7311/1460/5705/331/5682/7316/5728/5702/10273/207/4734/5714/7314/6233/11060/5717 16 Human_coronavirus_229E R-HSA-2467813 Separation of Sister Chromatids 32/947 190/10654 3.006134888401622e-4 0.00108497282179093 5.373943493785114e-4 7514/7311/9184/5905/7277/4928/5518/10381/57122/5705/6232/8881/29882/5528/5682/8243/9126/7316/10376/5501/5529/7321/991/5702/10393/5714/7314/347688/996/6233/1778/5717 32 Human_coronavirus_229E R-HSA-451927 Interleukin-2 family signaling 12/947 44/10654 3.285335601190045e-4 0.001182344273666102 5.856230855989493e-4 5295/5777/3932/5293/6464/5290/6774/6850/6772/6654/2885/3635 12 Human_coronavirus_229E R-HSA-195258 RHO GTPase Effectors 48/947 327/10654 3.443909145002776e-4 0.001235871396035282 6.121354299839521e-4 7514/6093/9184/26999/5905/5170/367/1432/7277/4928/10499/5518/10381/57122/5590/387/999/60/6232/5300/71/5528/3688/391/1499/10376/7531/5501/5529/4690/991/2316/23028/695/10971/81624/6279/4771/5500/5594/6722/347688/1855/2885/4221/5595/1778/1027 48 Human_coronavirus_229E R-HSA-432142 Platelet sensitization by LDL 7/947 17/10654 3.7574812368967793e-4 0.0013445573884736054 6.659683343847643e-4 1432/5777/5518/338/5528/5529/5781 7 Human_coronavirus_229E R-HSA-1250196 SHC1 events in ERBB2 signaling 8/947 22/10654 3.89837305337001e-4 0.0013753810547844755 6.812355040040438e-4 6464/1956/3845/3265/1950/5782/6654/2885 8 Human_coronavirus_229E R-HSA-198753 ERK/MAPK targets 8/947 22/10654 3.89837305337001e-4 0.0013753810547844755 6.812355040040438e-4 1432/4208/5518/9252/5528/4205/5594/5595 8 Human_coronavirus_229E R-HSA-389357 CD28 dependent PI3K/Akt signaling 8/947 22/10654 3.89837305337001e-4 0.0013753810547844755 6.812355040040438e-4 2475/5295/5170/3932/57761/5290/2534/207 8 Human_coronavirus_229E R-HSA-5655332 Signaling by FGFR3 in disease 8/947 22/10654 3.89837305337001e-4 0.0013753810547844755 6.812355040040438e-4 5295/2247/5290/5335/3845/3265/6654/2885 8 Human_coronavirus_229E R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 8/947 22/10654 3.89837305337001e-4 0.0013753810547844755 6.812355040040438e-4 5295/2247/5290/5335/3845/3265/6654/2885 8 Human_coronavirus_229E R-HSA-68949 Orc1 removal from chromatin 16/947 71/10654 3.9763798860140354e-4 0.0013989728674604 6.929206877883813e-4 8454/6500/1017/7311/4173/5705/6502/5682/7316/9978/5702/5714/4176/7314/6233/5717 16 Human_coronavirus_229E R-HSA-74752 Signaling by Insulin receptor 17/947 78/10654 4.0279948525273135e-4 0.0014131736130654487 6.999544127737848e-4 5295/5170/3643/57761/6464/2247/5290/529/3667/3845/3265/5781/3630/5594/6654/2885/5595 17 Human_coronavirus_229E R-HSA-9022692 Regulation of MECP2 expression and activity 10/947 33/10654 4.0691359962406135e-4 0.001423630866651312 7.051339609377519e-4 818/815/8841/25942/2290/9611/28996/3065/3066/9612 10 Human_coronavirus_229E R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 16/947 72/10654 4.698819141716593e-4 0.0016348246099712025 8.097396450661923e-4 7311/5705/6502/8881/29882/5682/7316/7321/991/5702/10393/5714/7314/996/6233/5717 16 Human_coronavirus_229E R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 16/947 72/10654 4.698819141716593e-4 0.0016348246099712025 8.097396450661923e-4 7311/9184/5705/8881/29882/5682/7316/7321/991/5702/10393/5714/7314/996/6233/5717 16 Human_coronavirus_229E R-HSA-2428928 IRS-related events triggered by IGF1R 13/947 52/10654 4.757291265693191e-4 0.0016505960855554276 8.175513631941483e-4 5295/5170/3479/57761/2247/5290/3667/3845/3265/5781/3481/6654/2885 13 Human_coronavirus_229E R-HSA-179812 GRB2 events in EGFR signaling 6/947 13/10654 4.819914153266197e-4 0.0016631352133248197 8.237620776692662e-4 1956/3845/3265/1950/6654/2885 6 Human_coronavirus_229E R-HSA-209543 p75NTR recruits signalling complexes 6/947 13/10654 4.819914153266197e-4 0.0016631352133248197 8.237620776692662e-4 7311/4615/7316/8878/7314/6233 6 Human_coronavirus_229E R-HSA-5676590 NIK-->noncanonical NF-kB signaling 14/947 59/10654 5.188306537754536e-4 0.0017853460305259443 8.842939189078387e-4 8454/6500/1147/7311/5971/8945/5705/5682/7316/5702/5714/7314/6233/5717 14 Human_coronavirus_229E R-HSA-187687 Signalling to ERKs 10/947 34/10654 5.311227526331809e-4 0.0018226507576701507 9.02771201628444e-4 5898/1432/6464/3845/3265/5603/5594/6654/2885/5595 10 Human_coronavirus_229E R-HSA-5675221 Negative regulation of MAPK pathway 11/947 40/10654 5.354762835640738e-4 0.0018325836843500727 9.076910471428872e-4 7311/5518/3845/5528/7316/3265/5529/5594/7314/6233/5595 11 Human_coronavirus_229E R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 15/947 66/10654 5.436477741425803e-4 0.001855493490008372 9.190384282559066e-4 7311/3091/5705/2034/7323/5682/7316/9978/7321/5702/8453/5714/7314/6233/5717 15 Human_coronavirus_229E R-HSA-373753 Nephrin family interactions 8/947 23/10654 5.515951360069558e-4 0.0018775162352973889 9.299464423908455e-4 5295/88/6711/5290/81/2534/4690/87 8 Human_coronavirus_229E R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 16/947 73/10654 5.531087791374129e-4 0.0018775800718826771 9.299780610816814e-4 7311/9184/5705/8881/29882/5682/7316/7321/991/5702/10393/5714/7314/996/6233/5717 16 Human_coronavirus_229E R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 7/947 18/10654 5.679966097815429e-4 0.001912610568057957 9.473289018791925e-4 5295/5290/6774/7750/6772/2885/613 7 Human_coronavirus_229E R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 7/947 18/10654 5.679966097815429e-4 0.001912610568057957 9.473289018791925e-4 2033/1874/3276/7027/7157/5933/5111 7 Human_coronavirus_229E R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 7/947 18/10654 5.679966097815429e-4 0.001912610568057957 9.473289018791925e-4 1956/3845/3265/5594/6654/2885/5595 7 Human_coronavirus_229E R-HSA-5358351 Signaling by Hedgehog 26/947 149/10654 6.193633369698028e-4 0.0020790544510988587 0.0010297696786787003 374654/8454/6500/57154/7311/7277/2932/8945/10381/5705/6469/64750/5573/2735/132884/5682/7316/10376/9978/5702/10956/83737/5714/7314/6233/5717 26 Human_coronavirus_229E R-HSA-5610783 Degradation of GLI2 by the proteasome 14/947 60/10654 6.223920968257729e-4 0.0020790544510988587 0.0010297696786787003 8454/6500/7311/2932/8945/5705/5682/7316/9978/5702/5714/7314/6233/5717 14 Human_coronavirus_229E R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 14/947 60/10654 6.223920968257729e-4 0.0020790544510988587 0.0010297696786787003 8454/6500/7311/2932/8945/5705/5682/7316/9978/5702/5714/7314/6233/5717 14 Human_coronavirus_229E R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 15/947 67/10654 6.440221677616476e-4 0.0021456017047974253 0.0010627309818431769 7311/5705/8881/29882/5682/7316/7321/991/5702/10393/5714/7314/996/6233/5717 15 Human_coronavirus_229E R-HSA-5218920 VEGFR2 mediated vascular permeability 9/947 29/10654 6.50893268456428e-4 0.002162756468733528 0.0010712278520126678 2475/7409/5170/57761/857/1499/1500/207/7410 9 Human_coronavirus_229E R-HSA-5696400 Dual Incision in GG-NER 11/947 41/10654 6.739196640547111e-4 0.002227481836980835 0.001103286763036937 7311/1642/6117/8450/7316/9978/142/5111/7314/6233/8451 11 Human_coronavirus_229E R-HSA-8875878 MET promotes cell motility 11/947 41/10654 6.739196640547111e-4 0.002227481836980835 0.001103286763036937 1281/3082/1277/1280/3912/2335/3688/1278/3911/3915/2885 11 Human_coronavirus_229E R-HSA-9615710 Microautophagy 10/947 35/10654 6.851430380266627e-4 0.0022586342670905205 0.0011187167715810407 7311/10226/51652/10013/5116/7431/7316/3312/7314/6233 10 Human_coronavirus_229E R-HSA-69620 Cell Cycle Checkpoints 43/947 293/10654 6.915721834596432e-4 0.0022738603728411307 0.0011262583643556051 672/7514/1017/7311/9184/5905/7341/4928/4173/5518/472/57122/5705/6232/6117/8881/29882/5528/5682/7316/7531/1029/993/5501/5529/7465/7321/991/5702/7157/1026/10971/10393/5714/4176/51588/7314/996/6233/1778/5717/1027/4194 43 Human_coronavirus_229E R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 13/947 54/10654 7.027420892774092e-4 0.0023045536922517646 0.0011414609722768965 10450/7311/1642/2033/8450/7316/9978/7874/10987/5430/7314/6233/8451 13 Human_coronavirus_229E R-HSA-5687128 MAPK6/MAPK4 signaling 18/947 89/10654 7.156746450860561e-4 0.002340852484968975 0.0011594400088976403 3315/7514/2308/7311/2118/3725/5705/2309/5682/7316/5702/8202/5597/5714/4609/7314/6233/5717 18 Human_coronavirus_229E R-HSA-69306 DNA Replication 23/947 127/10654 7.364456883134321e-4 0.002402534505251093 0.0011899915291681158 8454/6500/1017/7311/4173/5705/6502/6117/8881/29882/5682/7316/9978/7321/5702/10393/5714/5111/4176/7314/996/6233/5717 23 Human_coronavirus_229E R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 16/947 75/10654 7.579216644837369e-4 0.0024661907010144393 0.0012215208718567997 7311/9184/5705/8881/29882/5682/7316/7321/991/5702/10393/5714/7314/996/6233/5717 16 Human_coronavirus_229E R-HSA-3371571 HSF1-dependent transactivation 8/947 24/10654 7.635837105861535e-4 0.0024781941614889116 0.0012274662667113199 2475/818/3303/1410/1387/815/2033/3312 8 Human_coronavirus_229E R-HSA-8951664 Neddylation 36/947 234/10654 7.739231475662722e-4 0.002505276993152675 0.0012408805757234587 8454/6500/5931/7311/3091/1154/54165/8945/26270/5705/2034/6502/8065/1642/11091/8450/7323/5682/7316/9978/10238/7321/10987/5702/8453/51676/5714/9817/7704/10116/7314/6233/8451/5717/26094/5929 36 Human_coronavirus_229E R-HSA-73893 DNA Damage Bypass 12/947 48/10654 7.787841121091985e-4 0.0025145317347279005 0.0012454645115858106 7311/9636/7706/1642/6117/8450/7316/9978/5111/7314/6233/8451 12 Human_coronavirus_229E R-HSA-5686938 Regulation of TLR by endogenous ligand 7/947 19/10654 8.308832195709474e-4 0.002675870060977205 0.0013253764717042645 2266/2243/7099/2244/338/3929/6279 7 Human_coronavirus_229E R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 13/947 55/10654 8.467403775474251e-4 0.0027199639749349515 0.0013472164844003992 8454/6500/7311/8945/5705/5682/7316/991/5702/5714/7314/6233/5717 13 Human_coronavirus_229E R-HSA-5610787 Hedgehog 'off' state 21/947 113/10654 8.71305404851603e-4 0.0027917336441163607 0.0013827644851431187 374654/8454/6500/7311/7277/2932/8945/10381/5705/5573/2735/5682/7316/10376/9978/5702/83737/5714/7314/6233/5717 21 Human_coronavirus_229E R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 16/947 76/10654 8.824987133849532e-4 0.0028204030127519115 0.0013969646166077604 7311/9184/5705/8881/29882/5682/7316/7321/991/5702/10393/5714/7314/996/6233/5717 16 Human_coronavirus_229E R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 20/947 106/10654 9.408225206713435e-4 0.002992902873650903 0.0014824049600466675 7311/867/1956/6857/29924/160/9146/338/7018/7316/1950/10987/2060/7314/30011/29979/6233/1601/2885/29988 20 Human_coronavirus_229E R-HSA-201722 Formation of the beta-catenin:TCF transactivating complex 18/947 91/10654 9.414274094516964e-4 0.002992902873650903 0.0014824049600466675 9070/51176/1387/8607/2033/6597/1499/864/3065/7088/8313/8085/83439/6934/4609/4221/6932/5929 18 Human_coronavirus_229E R-HSA-159782 Removal of aminoterminal propeptides from gamma-carboxylated proteins 5/947 10/10654 9.460051280568538e-4 0.002992902873650903 0.0014824049600466675 5624/2621/2147/5627/5045 5 Human_coronavirus_229E R-HSA-390450 Folding of actin by CCT/TriC 5/947 10/10654 9.460051280568538e-4 0.002992902873650903 0.0014824049600466675 10694/6950/60/10576/908 5 Human_coronavirus_229E R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 12/947 49/10654 9.494023847845508e-4 0.0029961040082648136 0.0014839905035907684 1017/5325/28984/2033/1874/3276/7027/7157/1026/5933/5111/1027 12 Human_coronavirus_229E R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 13/947 56/10654 0.0010146936730253543 0.0031941234419043734 0.0015820708633636311 3315/7311/3303/26986/5705/5682/7316/3312/5702/5714/7314/6233/5717 13 Human_coronavirus_229E R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 8/947 25/10654 0.001036425006750887 0.0032301484081367596 0.0015999142718813484 1432/4208/5518/9252/5528/4205/5594/5595 8 Human_coronavirus_229E R-HSA-2029485 Role of phospholipids in phagocytosis 8/947 25/10654 0.001036425006750887 0.0032301484081367596 0.0015999142718813484 5295/3708/3710/5290/5335/5336/6850/3709 8 Human_coronavirus_229E R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus 8/947 25/10654 0.001036425006750887 0.0032301484081367596 0.0015999142718813484 7311/1956/7316/1950/4904/7314/6233/11060 8 Human_coronavirus_229E R-HSA-937041 IKK complex recruitment mediated by RIP1 8/947 25/10654 0.001036425006750887 0.0032301484081367596 0.0015999142718813484 1147/7311/7099/7323/7316/7321/7314/6233 8 Human_coronavirus_229E R-HSA-1226099 Signaling by FGFR in disease 14/947 63/10654 0.0010438922908428357 0.003237354857527412 0.0016034836748229134 5295/2247/5290/5335/3845/4686/3265/6774/5430/7750/6772/6654/2885/613 14 Human_coronavirus_229E R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 14/947 63/10654 0.0010438922908428357 0.003237354857527412 0.0016034836748229134 7311/5705/8881/29882/5682/7316/7321/5702/10393/5714/7314/996/6233/5717 14 Human_coronavirus_229E R-HSA-5632684 Hedgehog 'on' state 17/947 85/10654 0.0011350700602482228 0.003511448265201399 0.0017392439865353893 374654/57154/7311/5705/6469/64750/2735/132884/5682/7316/9978/5702/83737/5714/7314/6233/5717 17 Human_coronavirus_229E R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 7/947 20/10654 0.0011811420019387216 0.0035817745712402663 0.0017740770797879627 9184/8881/29882/7321/991/10393/996 7 Human_coronavirus_229E R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 7/947 20/10654 0.0011811420019387216 0.0035817745712402663 0.0017740770797879627 9184/8881/29882/7321/991/10393/996 7 Human_coronavirus_229E R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 7/947 20/10654 0.0011811420019387216 0.0035817745712402663 0.0017740770797879627 1147/7311/7323/7316/7321/7314/6233 7 Human_coronavirus_229E R-HSA-1170546 Prolactin receptor signaling 6/947 15/10654 0.001203430628235185 0.0035817745712402663 0.0017740770797879627 8454/6500/8945/9978/5781/1442 6 Human_coronavirus_229E R-HSA-372708 p130Cas linkage to MAPK signaling for integrins 6/947 15/10654 0.001203430628235185 0.0035817745712402663 0.0017740770797879627 2266/2243/7450/2244/2335/3690 6 Human_coronavirus_229E R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 6/947 15/10654 0.001203430628235185 0.0035817745712402663 0.0017740770797879627 2932/5518/5528/1499/8312/5529 6 Human_coronavirus_229E R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 6/947 15/10654 0.001203430628235185 0.0035817745712402663 0.0017740770797879627 2932/5518/5528/1499/8312/5529 6 Human_coronavirus_229E R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 6/947 15/10654 0.001203430628235185 0.0035817745712402663 0.0017740770797879627 2932/5518/5528/1499/8312/5529 6 Human_coronavirus_229E R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 6/947 15/10654 0.001203430628235185 0.0035817745712402663 0.0017740770797879627 2932/5518/5528/1499/8312/5529 6 Human_coronavirus_229E R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 6/947 15/10654 0.001203430628235185 0.0035817745712402663 0.0017740770797879627 2932/5518/5528/1499/8312/5529 6 Human_coronavirus_229E R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 6/947 15/10654 0.001203430628235185 0.0035817745712402663 0.0017740770797879627 2932/5518/5528/1499/8312/5529 6 Human_coronavirus_229E R-HSA-75892 Platelet Adhesion to exposed collagen 6/947 15/10654 0.001203430628235185 0.0035817745712402663 0.0017740770797879627 4067/1277/7450/2534/3688/1278 6 Human_coronavirus_229E R-HSA-8956320 Nucleobase biosynthesis 6/947 15/10654 0.001203430628235185 0.0035817745712402663 0.0017740770797879627 3615/158/3614/8833/2618/790 6 Human_coronavirus_229E R-HSA-937039 IRAK1 recruits IKK complex 6/947 15/10654 0.001203430628235185 0.0035817745712402663 0.0017740770797879627 1147/7311/7316/57162/7314/6233 6 Human_coronavirus_229E R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 6/947 15/10654 0.001203430628235185 0.0035817745712402663 0.0017740770797879627 3665/7311/4615/7316/7314/6233 6 Human_coronavirus_229E R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 6/947 15/10654 0.001203430628235185 0.0035817745712402663 0.0017740770797879627 1147/7311/7316/57162/7314/6233 6 Human_coronavirus_229E R-HSA-447115 Interleukin-12 family signaling 13/947 57/10654 0.0012096138900901702 0.0035831958630972967 0.001774781055221675 5898/10148/6950/3313/6175/3458/7297/27250/6774/3586/6772/6647/821 13 Human_coronavirus_229E R-HSA-69541 Stabilization of p53 13/947 57/10654 0.0012096138900901702 0.0035831958630972967 0.001774781055221675 7311/472/5705/5682/7316/1029/5702/7157/5714/7314/6233/5717/4194 13 Human_coronavirus_229E R-HSA-3232142 SUMOylation of ubiquitinylation proteins 10/947 38/10654 0.0013808713587550483 0.004074316355156075 0.002018036344198157 9972/7341/4928/9063/57122/8021/7329/5371/51588/8554 10 Human_coronavirus_229E R-HSA-901042 Calnexin/calreticulin cycle 8/947 26/10654 0.0013818939230067582 0.004074316355156075 0.002018036344198157 7311/23193/7316/2923/10956/7314/6233/821 8 Human_coronavirus_229E R-HSA-212165 Epigenetic regulation of gene expression 25/947 149/10654 0.00139619307025579 0.004106834885810942 0.002034142991547324 57504/5931/8850/23451/5928/2932/29947/22823/57459/23411/60/25942/2033/79595/23512/8819/2648/10284/2146/3065/3066/7270/6996/6839/23309 25 Human_coronavirus_229E R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 15/947 72/10654 0.0014148461685360584 0.004151978475890863 0.0020565029158996816 1017/7311/5705/8881/29882/5682/7316/7321/5702/10393/5714/7314/996/6233/5717 15 Human_coronavirus_229E R-HSA-5626467 RHO GTPases activate IQGAPs 9/947 32/10654 0.0014297671868385524 0.0041859850505110065 0.002073346601451563 7277/10381/999/60/71/1499/10376/347688/4221 9 Human_coronavirus_229E R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 14/947 65/10654 0.0014411068040105766 0.004209372432179731 0.0020849305291805406 10450/7311/1642/6117/2033/8450/7316/9978/7874/5430/5111/7314/6233/8451 14 Human_coronavirus_229E R-HSA-4615885 SUMOylation of DNA replication proteins 11/947 45/10654 0.001558150400692893 0.00454068887069669 0.0022490337936487965 5905/9972/7341/4928/6613/57122/10401/8021/7329/5111/51588 11 Human_coronavirus_229E R-HSA-159854 Gamma-carboxylation, transport, and amino-terminal cleavage of proteins 5/947 11/10654 0.0016079441208320907 0.004632059210470427 0.0022942901386088016 5624/2621/2147/5627/5045 5 Human_coronavirus_229E R-HSA-4755510 SUMOylation of immune response proteins 5/947 11/10654 0.0016079441208320907 0.004632059210470427 0.0022942901386088016 7341/10401/5970/7329/51588 5 Human_coronavirus_229E R-HSA-9020956 Interleukin-27 signaling 5/947 11/10654 0.0016079441208320907 0.004632059210470427 0.0022942901386088016 10148/7297/6774/6772/821 5 Human_coronavirus_229E R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 5/947 11/10654 0.0016079441208320907 0.004632059210470427 0.0022942901386088016 3845/3265/5781/6654/2885 5 Human_coronavirus_229E R-HSA-9614399 Regulation of localization of FOXO transcription factors 5/947 11/10654 0.0016079441208320907 0.004632059210470427 0.0022942901386088016 2308/2309/207/10971/4303 5 Human_coronavirus_229E R-HSA-6798695 Neutrophil degranulation 62/947 480/10654 0.001615598403180105 0.004643459026073712 0.002299936544091153 5004/10450/1675/6093/3685/10694/1667/2512/3303/1460/1432/5777/4318/3837/226/64333/197/387/5788/5284/5005/5265/8560/4790/3615/1/83858/2219/3240/56888/7305/4311/391/1938/3614/10576/3312/5657/5660/230/1915/2547/2896/966/5702/10875/203068/1315/823/23071/10075/6279/5768/10120/5594/1654/4069/114790/54472/5473/1778/5717 62 Human_coronavirus_229E R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 12/947 52/10654 0.001657167918773388 0.004752061429176656 0.002353728046130912 7311/2932/5705/1019/5682/7316/595/5702/5714/7314/6233/5717 12 Human_coronavirus_229E R-HSA-6782135 Dual incision in TC-NER 14/947 66/10654 0.0016827303889750426 0.004814372137933151 0.0023845909600389644 10450/7311/1642/6117/2033/8450/7316/9978/7874/5430/5111/7314/6233/8451 14 Human_coronavirus_229E R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 17/947 88/10654 0.0016922687741034346 0.004830658136986168 0.002392657525107966 8454/6500/7311/7277/8945/5518/5116/9662/7316/1453/7531/203068/55755/5500/7314/6233/1778 17 Human_coronavirus_229E R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 10/947 39/10654 0.001711654010773996 0.004874914824335916 0.0024145781605619566 10694/26270/6950/8841/10576/908/10238/6774/7157/8237 10 Human_cytomegalovirus R-HSA-9006925 Intracellular signaling by second messengers 281/5218 305/10654 7.714907616514995e-61 1.0862589924053113e-57 4.149808202146487e-58 5295/1912/2308/5689/374/3725/6591/3643/2250/5335/5682/23035/5291/1822/1459/5526/9112/817/6045/5578/7039/5582/27327/80012/3082/1460/941/143471/2064/5705/5709/5695/107/1457/1911/4734/11060/5711/5928/10325/5683/145957/2534/23512/9965/57332/5699/2444/2264/3630/5702/192669/1107/8975/3654/5371/9542/2885/2475/51135/8660/5518/1386/10670/2252/4343/2253/80351/64121/5696/5691/7314/5879/5515/5718/818/1839/5290/3667/8823/90865/2065/23186/5700/3815/122706/5707/5567/2146/51564/5594/2069/84335/84232/8074/7249/23198/112/2260/5573/5528/111/2249/6714/2099/9861/7101/81847/2248/5519/2932/84733/57459/2247/5698/5880/10000/5692/5713/5710/3066/7157/5613/5719/6233/5580/7409/2246/2251/5154/3932/2931/3710/331/8726/196883/8394/115/255324/26523/7874/801/5781/57521/23608/940/6015/253260/28956/805/5170/3838/572/23239/389541/9219/8535/4303/5568/930/5931/58528/5706/6199/113/2263/4233/8658/5714/1108/2122/64223/5566/10014/8503/5688/5159/5687/5708/3084/54815/6009/5529/816/7189/208/9365/5577/5704/10718/79109/55004/57504/7311/5293/1956/648/2549/5694/23466/53615/109/5595/3556/5516/1147/8822/27161/815/5684/8841/685/5305/5720/2309/5468/5525/5575/842/5978/10273/207/5690/57690/5717/1027/9491/8817/114/3708/10197/108/192670/4615/153129/2100/2254/7316/10213/1950/1026/55615/50852/10768/26281/57167/10818/5715/1958/2261/5701/5576/5685/2255/8649/3164/5686/391/5728/6615/3065/2066/27006/23028/942/5987/23112/10542/5527/5716/1385/5155/4254/5296/5581/808/5693/5721/5137/5156/4193 281 Human_cytomegalovirus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 234/5218 244/10654 4.9716820582223793e-60 3.500064168988555e-57 1.3371208061850715e-57 8449/23165/6633/8683/6431/84271/55696/4904/51639/51585/9128/199746/23450/348995/57122/5431/9092/23511/81608/5435/6625/5433/51645/3190/1477/9416/65109/56339/22826/23279/8233/22938/988/23020/23225/6631/3181/5439/1660/9410/6638/57721/9877/9972/8021/3312/10907/10291/55746/26121/10262/7919/53981/6432/10084/8563/6430/51340/56001/6627/6936/83443/11051/80145/9129/9879/10081/8106/51690/27238/55749/5438/85313/10762/54883/22794/9785/11338/1655/9343/29107/3185/4116/6626/11157/285755/1478/24144/79902/9883/51213/10236/10250/4670/26097/51362/10465/55660/25949/23283/2521/1977/3191/10285/6636/23524/10914/57187/6396/129401/79228/8175/2733/84950/3188/84324/56259/5725/1994/10450/7536/4928/2963/6635/5434/5903/220988/6632/10283/55706/7175/24148/154007/23350/5436/10523/6428/27258/10212/6637/55110/5093/55954/84321/6429/57819/4927/10181/2962/10898/10569/23658/6434/9295/84844/10482/51692/10421/11193/8086/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/81929/5440/55599/51691/10946/9631/27339/5430/79869/85437/11325/57703/3184/25804/29894/9589/11017/51503/3178/79023/5441/23636/3183/79622/10594/4686/8189/23398/10713/53371/10978/5546/7307/10772/9688/9984/5437/6629/10189/10949/51729/11066/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/84248/6427/5356/84991/8480/10992/55339/6628 234 Human_cytomegalovirus R-HSA-3700989 Transcriptional Regulation by TP53 323/5218 365/10654 1.9982756435035836e-59 9.378573686843485e-57 3.5828731713344957e-57 6884/6875/834/5563/3725/9134/4436/83990/64769/9156/57060/1763/7531/1459/79370/7486/6874/10971/9997/133383/9212/5982/27327/7295/7533/2810/55367/1460/11200/472/53632/79813/5431/7001/639/5435/5433/1869/28996/84289/1457/6790/25904/29117/4194/1647/5928/1432/1387/4683/10325/56950/51499/2965/84126/8738/5439/192669/1107/8900/6873/5371/2475/672/55571/6881/51616/5518/1386/55835/10670/4513/4343/6117/11198/7159/57472/904/144455/85456/29883/51497/51230/637/64121/83695/7296/7314/5515/1263/27166/23368/9377/23774/6118/2176/3622/7027/6446/2936/7832/51422/7249/898/117584/27244/7534/332/5438/5934/64065/1351/116028/890/10769/983/1643/8797/9656/5519/27154/5458/83860/57459/2821/2177/10000/5985/2877/900/7994/2068/54541/3066/7157/5984/6233/1121/1025/2353/604/63970/839/7029/10419/5325/50484/5600/6883/7936/6829/79733/26523/7874/317/5608/5884/5810/57521/26155/26013/5875/253260/28956/5170/80010/2963/5434/83667/1820/7862/1029/389541/5457/9219/8445/7532/5436/55240/204851/6878/4869/5931/58528/4850/4292/580/11073/891/80196/54971/4331/5366/641/5111/1108/8148/246175/64223/2962/84883/6119/147923/3364/5571/10524/54457/4848/8812/144715/23019/1616/843/6794/54815/94241/1874/10128/25824/6009/1111/2071/8626/208/79109/55004/7311/7161/5562/6880/6908/5983/4697/5564/6882/5565/1020/53615/10397/8795/5432/665/7248/6877/7529/5516/1017/27161/27113/9891/6917/5440/27165/5305/8621/902/5883/25946/9540/5430/10111/8793/207/22974/57690/835/4849/1027/58484/3486/355/6749/545/5441/8794/192670/153129/8550/9337/7316/6872/2539/1026/54205/55615/5933/124446/5395/9150/6879/112858/5876/143686/10848/5437/9099/8649/28984/51755/2033/995/5728/3065/91875/23112/10498/10542/5527/2968/5932/8851/5300/7156/581/1327/3276/5052/138474/133746/1022/8178/10919/4193 323 Human_cytomegalovirus R-HSA-5663205 Infectious disease 335/5218 383/10654 8.181670418581899e-59 2.8799479873408285e-56 1.100219364182987e-56 3839/6158/6884/23165/6875/5689/51652/6138/2237/6227/7852/6206/6234/6191/162/6128/5682/6132/6129/27243/6874/6176/1174/811/6224/6146/348995/6154/143471/6202/57122/5705/3981/6169/5431/23511/5435/5709/6175/9978/5433/6218/5695/2960/292/567/51271/6173/23279/5605/6167/5711/23327/116832/29082/8732/23225/5683/2965/2534/6156/27183/5699/6143/5439/5702/6456/6873/3836/6139/30011/2885/163/9972/6881/51616/3921/8021/7040/1794/11198/904/51497/5062/55746/6208/5696/6170/5691/92421/7296/7314/5879/5718/137492/3303/8945/6203/51606/1839/161/5606/6147/25978/5700/51160/122706/5707/2959/8027/10053/6222/2060/8106/23198/9636/10015/91782/5438/6134/10762/79720/6155/1500/4836/926/9397/6714/6231/9861/79902/6142/9883/23521/83860/51510/999/5698/9146/6455/5692/5713/5710/2068/5902/6207/5478/5719/6233/6844/7514/1025/3932/1213/5610/1211/6188/6396/129401/6883/7936/1175/6829/801/5608/8907/200916/6122/2957/940/805/6230/60489/1173/4928/2963/3838/5434/5903/6857/6194/55706/7175/6166/1938/5436/6136/6878/6125/4869/821/5706/6232/160/6160/6616/5611/920/4233/4331/5714/6193/4927/6210/6229/8148/6205/2962/10898/3840/5688/54457/8812/5687/5708/128866/140801/6235/6181/2071/5901/8086/5704/3326/7311/6223/25873/93343/6880/6908/7251/8905/5694/3304/1104/2547/9045/6882/2961/6187/6416/5432/6168/22916/1234/6157/6137/6877/5905/6144/3837/6917/81929/5440/164/5684/9349/8065/4736/5720/902/51121/9631/5604/1499/3159/6159/6217/3843/5430/6152/5690/5045/7520/5717/9491/6500/127833/6749/51065/6141/79023/6123/5441/23636/10197/919/130340/6164/4686/7316/10213/6872/53371/3055/6209/9688/11224/6165/6130/9150/6879/5715/9525/6204/5701/2958/867/6228/5437/5685/3320/8815/5686/6124/5609/2968/5716/9844/6189/808/6135/6201/375/6161/138474/1022/5693/10254/5721/6457/8178/8480/6133/291 335 Human_cytomegalovirus R-HSA-1257604 PIP3 activates AKT signaling 247/5218 264/10654 5.276279886512288e-57 1.4858004160418604e-54 5.67616636212164e-55 5295/1912/2308/5689/374/3725/6591/3643/2250/5682/23035/5291/1822/1459/5526/9112/6045/7039/27327/80012/3082/1460/941/143471/2064/5705/5709/5695/1457/1911/4734/11060/5711/5928/10325/5683/145957/2534/23512/9965/57332/5699/2444/2264/3630/5702/192669/1107/8975/3654/5371/9542/2885/2475/51135/8660/5518/1386/10670/2252/4343/2253/80351/64121/5696/5691/7314/5879/5515/5718/1839/5290/3667/8823/90865/2065/23186/5700/3815/122706/5707/2146/51564/5594/2069/84335/84232/8074/7249/23198/2260/5528/2249/6714/2099/9861/7101/81847/2248/5519/2932/84733/57459/2247/5698/5880/10000/5692/5713/5710/3066/7157/5719/6233/7409/2246/2251/5154/3932/2931/331/8726/8394/255324/26523/7874/5781/57521/23608/940/6015/253260/28956/5170/572/23239/389541/9219/8535/4303/930/5931/58528/5706/6199/2263/4233/8658/5714/1108/2122/64223/10014/8503/5688/5159/5687/5708/3084/54815/6009/5529/7189/208/9365/5704/10718/79109/55004/57504/7311/5293/1956/648/2549/5694/23466/53615/5595/3556/5516/1147/8822/27161/5684/8841/685/5305/5720/2309/5468/5525/842/5978/10273/207/5690/57690/5717/1027/9491/8817/10197/192670/4615/153129/2100/2254/7316/10213/1950/1026/55615/50852/26281/57167/10818/5715/1958/2261/5701/5685/2255/8649/3164/5686/391/5728/6615/3065/2066/27006/23028/942/5987/23112/10542/5527/5716/1385/5155/4254/5296/5693/5721/5156/4193 247 Human_cytomegalovirus R-HSA-5663202 Diseases of signal transduction 324/5218 377/10654 5.650047704772907e-53 1.3258778613867087e-50 5.06521820550694e-51 5295/8454/2308/27123/5689/374/4893/11052/2250/5335/71/79718/5682/5291/892/5526/817/1452/7039/9530/613/9372/182/5908/3082/941/143471/23385/2064/5705/5431/6776/5435/5709/9978/5433/5695/8546/9759/9612/5605/4609/4089/22938/5037/3549/5711/1387/3717/4088/2244/6907/5683/145957/324/2534/3690/408/9965/5699/6400/8312/11064/5439/2264/5702/4296/5894/6868/9794/9542/2885/2475/8660/51009/8826/9846/5518/2252/6469/4140/7040/2253/3845/388585/3265/80351/4763/5696/7750/5691/28514/7314/5879/5515/5718/818/8805/1839/5290/3667/8823/79885/2065/2648/9734/55869/5700/3815/122706/5707/10956/8844/51564/7094/8322/55534/5594/3280/2069/84335/8074/7249/23198/84441/7414/10533/10013/23164/2260/5438/5528/83933/89780/102/57085/2249/6714/2099/50846/9861/2248/5519/8850/399687/2932/7046/2247/5698/5880/10000/5692/5713/2335/1445/5710/3066/2280/5719/6233/2266/7409/2246/4040/27248/2251/5154/3932/2931/2243/7855/6777/255324/369/801/5781/5663/940/1523/57670/253260/805/5170/2963/5434/7276/6464/572/283455/3674/5436/4303/409/930/5706/6199/10046/84447/673/6774/2263/4233/8658/1024/5714/6772/6934/64223/10014/2962/8503/5688/5159/5687/5708/3084/26508/5529/816/4087/208/9365/6654/5704/10718/79109/56829/7048/23493/7311/5293/7450/1956/11160/60/9444/2549/5694/5950/4851/5432/22916/11140/7529/5595/5516/4000/1147/8822/27044/815/5440/5684/22906/8841/685/5720/1487/2309/5604/1499/10018/5525/10142/842/139285/5430/23462/207/5690/5717/1027/9491/6500/8817/5441/10197/2100/2254/4686/7316/10213/1950/9611/1026/55615/50852/26281/10818/7415/5715/2261/5701/867/5437/5685/2255/3164/3320/5686/2033/54894/391/55294/5728/3065/2066/27006/942/5527/1488/5716/1385/5906/5155/4254/5296/808/3516/5693/5721/5245/5156/4193 324 Human_cytomegalovirus R-HSA-72172 mRNA Splicing 185/5218 191/10654 1.0277231607099486e-49 2.067191728970868e-47 7.897241129665922e-48 8449/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/5431/9092/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/8233/22938/988/23020/6631/3181/5439/1660/9410/6638/3312/10907/10291/26121/10262/53981/6432/10084/6430/51340/6627/6936/83443/11051/9129/9879/10081/8106/51690/27238/55749/5438/85313/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/10236/10250/4670/51362/10465/55660/25949/23283/2521/3191/10285/6636/23524/10914/8175/84950/3188/56259/5725/1994/10450/7536/2963/6635/5434/220988/6632/10283/24148/154007/23350/5436/10523/6428/27258/6637/55110/5093/55954/6429/57819/10181/2962/10898/10569/23658/6434/9295/84844/51692/10421/11193/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/55599/51691/10946/27339/5430/79869/85437/11325/57703/3184/25804/29894/11017/51503/3178/5441/3183/79622/10594/4686/8189/23398/10713/10978/5546/7307/10772/5437/6629/10189/10949/51729/11066/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/84991/10992/55339/6628 185 Human_cytomegalovirus R-HSA-72163 mRNA Splicing - Major Pathway 177/5218 183/10654 2.7574163304802363e-47 4.853052741645216e-45 1.853999664309738e-45 8449/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/5431/9092/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/22938/988/23020/6631/3181/5439/1660/9410/6638/3312/10907/10291/26121/10262/53981/6432/10084/6430/51340/6627/6936/83443/11051/9129/9879/8106/51690/27238/55749/5438/85313/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/10236/10250/4670/51362/10465/55660/25949/23283/2521/3191/10285/6636/23524/10914/8175/84950/3188/56259/5725/1994/10450/7536/2963/6635/5434/220988/6632/10283/24148/23350/5436/10523/6428/27258/6637/55110/5093/6429/57819/10181/2962/10898/10569/23658/6434/9295/84844/51692/10421/11193/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/51691/10946/27339/5430/79869/11325/57703/3184/25804/29894/11017/51503/3178/5441/3183/10594/4686/8189/23398/10713/10978/5546/7307/10772/5437/6629/10189/10949/51729/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/84991/10992/55339/6628 177 Human_cytomegalovirus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 378/5218 473/10654 1.1002844863858748e-45 1.721333952034791e-43 6.5759692695109e-44 5295/3675/374/5777/627/3643/9252/4893/857/2250/2670/5335/71/5579/5770/5291/26469/1848/10653/256076/5578/7039/3249/1785/5908/3082/51741/23385/2064/535/1280/1289/5431/50617/6696/6776/5435/3688/10312/5433/5753/5327/7423/4734/10413/5605/3910/8569/1290/5898/1432/3717/55824/145957/2534/3690/9965/1215/5439/2264/5603/3630/6456/83737/6868/7072/4145/9542/30011/2885/2475/8660/163/7073/6196/9846/1759/5518/8440/2252/8874/9564/2253/6197/3845/1285/3265/1399/8877/5062/10603/10252/51231/56034/5829/7314/5879/5515/6387/5607/54106/51606/8038/1839/3918/161/5290/3667/8823/6678/2065/5340/526/3815/5567/8027/10006/537/9550/1849/1284/2060/5594/2069/8074/284217/9101/23118/5921/6778/2260/5438/348/5528/9306/1500/1795/3185/11059/102/9261/2249/6714/2099/2248/5519/5598/4208/4670/2567/4909/2321/2247/4914/529/10810/10000/9146/6455/2335/64759/6195/3728/8471/1445/84951/3925/6233/7525/7410/5580/2324/7409/2246/3685/1292/2251/5154/3932/1213/3791/1729/3710/1211/29924/1293/1535/5600/6777/255324/1175/523/6300/801/200734/5781/30849/5663/5725/1302/1291/253260/805/5170/1286/4908/1173/4688/1287/2963/5434/5800/5590/6464/80310/85440/5241/2904/5747/5782/7424/5436/10019/10193/5568/2322/7074/3315/2241/10451/4318/382/1277/160/3912/673/527/6774/2263/4233/10152/6772/8651/26052/7867/64223/5566/2962/1003/8503/5795/2889/5159/4067/3084/5771/1111/5796/998/3481/2886/3913/208/9365/6654/5867/10718/79109/5900/7311/2185/387/1956/60/2549/5058/1020/5432/3480/22916/11140/53916/4916/7529/63916/5595/25759/5516/8822/1845/10253/9402/5440/1282/8065/685/23543/26018/558/4915/1495/5604/1499/4690/1299/5430/10048/10273/207/7422/10458/5045/3178/8817/3708/5441/58513/2254/4686/7316/1950/9611/51072/9047/4205/5289/57498/55615/3915/1301/10768/26281/10818/1281/3673/23545/2261/867/5437/2255/53358/3320/4846/4803/2066/3914/27006/6285/1398/3187/5774/1385/9844/5228/5906/3479/5155/23163/4254/8851/5296/5581/581/808/10076/131873/1536/7057/1278/11033/10254/6457/51382/5156/161742/9296/2887/2242 378 Human_cytomegalovirus R-HSA-913531 Interferon Signaling 186/5218 199/10654 6.881517738515166e-43 9.689176975829355e-41 3.701532173032895e-41 80263/3839/3443/23165/5777/3442/5335/960/5770/3107/817/9021/348995/317649/3383/57122/11274/55223/3662/3115/23511/4684/567/4734/6672/3113/23279/3106/8672/3717/23225/3117/1973/11074/3836/5371/4599/684/9972/3133/3429/117854/8021/3127/91543/7334/4938/4261/55746/5696/7314/3445/818/115362/7412/10410/85363/9830/163351/9636/2634/3444/10762/2317/115361/103/3434/10475/3433/79902/23586/9883/3451/10437/3448/1981/10612/3458/3661/7324/1977/3439/51191/6233/5580/81603/10107/5610/10581/3452/4940/6396/3437/129401/6773/7297/5781/3430/3660/3446/8554/3135/3665/3120/4928/3838/5903/10379/55706/7175/3455/2316/2633/4600/3123/23650/2209/8638/25820/1982/7706/23087/9470/3122/3394/3663/6772/8651/4927/3659/3840/25939/2635/3440/5771/3454/816/8086/10346/9246/3716/7311/7318/7726/79097/3456/3105/1974/5595/815/3837/81929/3441/6737/51447/9631/23321/4281/3119/4502/54739/79023/2537/23636/3449/51127/7316/53371/8519/3664/9688/6041/1958/4939/388646/7341/6059/55128/3669/3134/5300/9775/80128/5495/5724/8480 186 Human_cytomegalovirus R-HSA-5633007 Regulation of TP53 Activity 155/5218 160/10654 8.543204382780642e-42 1.0935301609959222e-39 4.17758606660374e-40 6884/6875/5563/83990/64769/9156/1763/1459/7486/6874/133383/9212/5982/1460/11200/472/53632/79813/639/28996/84289/1457/6790/29117/4194/5928/1432/4683/56950/84126/1107/8900/6873/5371/2475/672/6881/51616/5518/6117/11198/7159/51230/83695/7314/5515/1263/23368/23774/6118/3622/6446/51422/117584/116028/890/983/5519/27154/5458/83860/57459/10000/5985/900/7994/3066/7157/5984/6233/10419/5600/6883/7874/5608/5884/5810/26155/26013/253260/5170/80010/7862/1029/5457/9219/8445/204851/6878/5931/580/11073/80196/54971/641/1108/8148/64223/6119/3364/5571/10524/54457/144715/1616/6794/54815/94241/1111/8626/208/79109/7311/7161/5562/6880/6908/5983/5564/6882/5565/1020/53615/6877/5516/1017/9891/5305/5883/25946/10111/207/22974/6749/545/8550/7316/6872/55615/6879/112858/10848/9099/2033/3065/91875/5527/5932/8851/5300/7156/138474/133746/10919/4193 155 Human_cytomegalovirus R-HSA-449147 Signaling by Interleukins 360/5218 461/10654 2.4817913930939978e-39 2.911968567896957e-37 1.1124521069044148e-37 5295/729230/8454/3605/7124/2308/834/1052/5689/3725/7291/5777/9252/1437/4790/5682/5291/26469/5783/1848/356/3593/246/9021/8878/5908/3082/5743/3091/941/143471/3383/5705/11009/6097/6657/3576/3313/3662/6776/3688/4985/5709/6175/9978/2920/5695/84868/1435/4792/7133/3606/4609/3603/5898/5711/4988/1432/3558/3717/4088/836/5683/2534/2162/5699/3181/5702/4001/3654/2885/51135/8660/282618/6196/3594/1154/9846/6347/5518/282617/1386/6382/9235/7040/3588/6197/4282/7334/3600/3312/1399/3551/282616/3569/5062/5696/5691/51231/4692/7314/3572/3596/5515/257397/3598/5718/54014/10148/8945/1326/5601/1072/3635/3592/5290/3667/6627/5606/90865/9049/11213/3587/7412/5700/122706/5707/27250/8767/1849/29110/1439/5594/4582/23198/23118/4312/9987/8517/6778/7534/6810/332/5528/4313/3565/3934/3976/3185/5970/5443/9261/3718/3627/9861/5519/5598/4208/3567/598/2247/5698/5692/5713/2335/595/6195/5710/3458/10454/7157/5478/5719/6233/7525/6844/7409/2353/604/6809/3932/7076/302/51561/3570/8835/5600/6777/6773/7850/7297/5781/5608/4791/3557/9655/3562/351/6464/3566/6597/5782/6351/7184/9180/3589/6775/50616/3684/3595/54472/821/4318/5706/3726/58480/301/4478/1438/6616/79155/6774/920/6850/1440/5714/6772/8651/7867/5566/8503/1901/3552/2889/5688/79923/5687/4067/29760/3636/5708/5602/29949/3656/57162/5771/998/6648/7189/163702/6654/5704/3716/7311/1270/6888/5293/2185/240/6655/6356/5008/5694/23765/246778/6416/1234/3586/3554/829/5595/3556/5516/1147/5778/1845/596/5684/5720/6885/2309/5604/4215/3561/3578/10392/207/5292/5451/7422/5690/3553/2625/1230/5717/2919/9491/6500/3568/25930/10197/4615/2357/1436/7316/10213/3560/6352/4314/1441/4205/3055/1026/6348/4793/3146/6647/6364/5715/7132/5701/867/6950/23291/5685/3320/5686/4843/9466/6288/942/6285/5609/1398/58985/948/5716/1385/53832/6363/3575/6845/5296/6935/3687/5599/7431/375/3977/3574/3559/3162/57161/1278/4170/5693/3689/5721/5724/5034 360 Human_cytomegalovirus R-HSA-2555396 Mitotic Metaphase and Anaphase 184/5218 202/10654 3.1102351749531447e-38 3.3686239433338676e-36 1.286907023806524e-36 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/5520/51529/4001/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/7444/5698/5692/5713/91687/119504/10376/5710/7324/83540/2010/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/26271/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/7443/1781/7316/10213/4085/55166/5715/5701/5685/8815/5686/79003/9126/9232/9700/5527/5716/701/57551/5693/5721 184 Human_cytomegalovirus R-HSA-2467813 Separation of Sister Chromatids 175/5218 190/10654 4.628374974635734e-38 4.654822831633652e-36 1.7782703849916243e-36 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/5698/5692/5713/91687/119504/10376/5710/7324/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7280/1778/5516/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/1781/7316/10213/4085/55166/5715/5701/5685/5686/79003/9126/9232/9700/5527/5716/701/57551/5693/5721 175 Human_cytomegalovirus R-HSA-68882 Mitotic Anaphase 183/5218 201/10654 5.884927045845857e-38 5.523984853700644e-36 2.1103141897734972e-36 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/5520/51529/4001/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/7444/5698/5692/5713/91687/119504/10376/5710/7324/83540/2010/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/7443/1781/7316/10213/4085/55166/5715/5701/5685/8815/5686/79003/9126/9232/9700/5527/5716/701/57551/5693/5721 183 Human_cytomegalovirus R-HSA-453274 Mitotic G2-G2/M phases 180/5218 198/10654 3.972424509765831e-37 3.4957335685939316e-35 1.335466397691013e-35 10844/8454/5689/440145/5682/7531/11190/203068/54801/51807/63943/347688/79441/143471/10381/5705/5116/5048/5709/9978/1869/5695/8655/6790/9702/5711/5928/7846/7840/5683/5699/11064/5702/5520/8900/28227/5518/55835/23332/7465/93323/5696/5691/7314/5515/5718/8945/4659/5700/122706/5707/1454/23198/993/890/983/9861/79959/5519/5698/5692/5713/80097/10376/5710/10540/7157/5719/6233/7514/54930/54820/1453/9793/4218/5500/84617/2305/11258/22981/8636/51512/7532/84962/55125/10382/121441/7277/5706/9133/286826/9814/23354/728642/891/9738/4331/1639/5714/55722/4957/5566/5688/5687/91750/7283/5708/22919/984/10426/22994/79866/1069/5577/5704/3326/55957/7311/10133/10383/5347/84790/80184/5694/22897/5108/7280/10806/1778/5516/115106/1017/22822/22995/55559/5684/994/5720/4605/902/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/1781/7316/10213/80321/1026/10121/1871/5715/84131/9088/5701/23291/5685/3320/5686/2033/995/10733/4751/80254/5716/23194/9662/55142/1022/8481/5693/5721/132660/55755 180 Human_cytomegalovirus R-HSA-69275 G2/M Transition 178/5218 196/10654 1.4146071682800874e-36 1.1716275840813902e-34 4.4759397089233737e-35 10844/8454/5689/440145/5682/7531/11190/203068/54801/51807/63943/347688/79441/143471/10381/5705/5116/5048/5709/9978/5695/8655/6790/9702/5711/5928/7846/7840/5683/5699/11064/5702/5520/8900/28227/5518/55835/23332/7465/93323/5696/5691/7314/5515/5718/8945/4659/5700/122706/5707/1454/23198/993/890/983/9861/79959/5519/5698/5692/5713/80097/10376/5710/10540/7157/5719/6233/7514/54930/54820/1453/9793/4218/5500/84617/2305/11258/22981/8636/51512/7532/84962/55125/10382/121441/7277/5706/9133/286826/9814/23354/728642/891/9738/4331/1639/5714/55722/4957/5566/5688/5687/91750/7283/5708/22919/984/10426/22994/79866/1069/5577/5704/3326/55957/7311/10133/10383/5347/84790/80184/5694/22897/5108/7280/10806/1778/5516/115106/1017/22822/22995/55559/5684/994/5720/4605/902/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/1781/7316/10213/80321/1026/10121/5715/84131/9088/5701/23291/5685/3320/5686/2033/995/10733/4751/80254/5716/23194/9662/55142/1022/8481/5693/5721/132660/55755 178 Human_cytomegalovirus R-HSA-162906 HIV Infection 204/5218 233/10654 3.9123926323201074e-36 3.060360459059284e-34 1.1691418918804532e-34 6884/23165/6875/5689/51652/2237/7852/162/5682/27243/6874/1174/348995/143471/57122/5705/3981/5431/23511/5435/5709/9978/5433/5695/2960/292/567/51271/23279/5711/23327/29082/8732/23225/5683/2965/2534/27183/5699/5439/5702/6873/3836/163/9972/6881/51616/8021/1794/11198/904/51497/5062/55746/5696/5691/92421/7314/5879/5718/137492/8945/51606/161/25978/5700/51160/122706/5707/2959/10053/23198/10015/91782/5438/10762/79720/4836/926/9397/9861/79902/9883/83860/51510/5698/5692/5713/5710/2068/5902/5478/5719/6233/7514/1025/3932/6396/129401/6883/7936/1175/6829/8907/2957/940/60489/1173/4928/2963/5434/5903/55706/7175/5436/6878/4869/5706/160/920/4331/5714/4927/8148/2962/5688/54457/8812/5687/5708/128866/2071/5901/8086/5704/7311/93343/6880/6908/7251/8905/5694/1104/2547/6882/2961/5432/22916/1234/6877/5905/3837/6917/81929/5440/164/5684/8065/5720/902/9631/3159/5430/5690/5045/7520/5717/9491/6500/6749/79023/5441/23636/10197/919/130340/4686/7316/10213/6872/53371/3055/9688/9150/6879/5715/9525/5701/2958/5437/5685/8815/5686/2968/5716/9844/375/138474/1022/5693/5721/8178/8480/291 204 Human_cytomegalovirus R-HSA-6807070 PTEN Regulation 135/5218 140/10654 9.142523845464096e-36 6.775091354954446e-34 2.5882712936466226e-34 1912/5689/3725/6591/5682/1822/1459/9112/6045/27327/80012/1460/143471/5705/5709/5695/1457/1911/4734/11060/5711/5928/10325/5683/23512/57332/5699/2444/5702/192669/1107/8975/5371/2475/1386/10670/4343/80351/64121/5696/5691/7314/5718/23186/5700/122706/5707/2146/51564/5594/84232/23198/9861/7101/81847/84733/57459/5698/10000/5692/5713/5710/3066/7157/5719/6233/331/8726/26523/7874/57521/23608/6015/28956/389541/9219/8535/5931/58528/5706/8658/5714/1108/2122/64223/10014/5688/5687/5708/54815/6009/208/5704/55004/57504/7311/648/5694/23466/53615/5595/27161/5684/8841/5720/5468/5978/10273/207/5690/57690/5717/9491/10197/192670/153129/7316/10213/57167/5715/1958/5701/5685/8649/5686/5728/6615/3065/23028/5987/23112/10542/5716/5693/5721 135 Human_cytomegalovirus R-HSA-453279 Mitotic G1-G1/S phases 142/5218 149/10654 1.0235870317198644e-35 7.206052703307846e-34 2.752910385309741e-34 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/1031/4998/5711/5928/10926/3717/5683/990/5699/5702/5520/8900/55388/28227/1030/5518/6117/5001/7465/5696/5691/7314/5515/6241/5718/6118/25/7027/5700/5707/7153/898/91768/5934/5557/993/890/1876/983/6714/9861/5519/6502/5698/10000/5692/5713/595/4175/5710/896/5719/6233/7298/7029/23649/1719/1163/1859/4172/26271/1019/5000/8318/1029/54107/4173/5706/286826/891/4331/5714/5111/51053/6119/5688/5687/91750/5427/4067/5708/1874/81620/208/1870/5704/55957/7311/5694/4176/5516/56655/1017/894/5684/5720/4605/902/8317/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5933/5426/4171/1871/5715/5701/5685/5686/1021/3065/5716/1022/5693/5721/7083/132660/1028 142 Human_cytomegalovirus R-HSA-168255 Influenza Life Cycle 138/5218 144/10654 1.4348875539540963e-35 9.620579409368417e-34 3.6753260153911943e-34 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/116832/23225/6156/6143/5439/3836/6139/9972/3921/8021/55746/6208/6170/3303/6203/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/7514/1213/1211/6188/6396/129401/200916/6122/6230/4928/2963/5434/5903/6194/55706/7175/6166/5436/6136/6125/821/6232/6160/5611/6193/4927/6210/6229/6205/2962/140801/6235/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/81929/5440/9349/4736/51121/9631/6159/6217/3843/5430/6152/51065/6141/79023/6123/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 138 Human_cytomegalovirus R-HSA-168254 Influenza Infection 146/5218 155/10654 6.042395925812462e-35 3.867133392519976e-33 1.4773513483685016e-33 3839/6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/116832/23225/6156/6143/5439/3836/6139/9972/3921/8021/7040/55746/6208/6170/3303/6203/6147/6222/8106/9636/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/7514/1213/5610/1211/6188/6396/129401/200916/6122/6230/4928/2963/3838/5434/5903/6194/55706/7175/6166/5436/6136/6125/821/6232/6160/5611/6193/4927/6210/6229/6205/2962/10898/3840/140801/6235/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/81929/5440/9349/4736/51121/9631/6159/6217/3843/5430/6152/51065/6141/79023/6123/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 146 Human_cytomegalovirus R-HSA-8856828 Clathrin-mediated endocytosis 139/5218 146/10654 7.848835614163767e-35 4.8048524107576455e-33 1.8355858118250276e-33 5869/374/85439/71/8674/5286/4738/7039/1212/23208/1785/29763/950/8871/10094/554/54874/55738/10980/22848/7037/2017/3482/408/9322/10987/6456/185/8976/30011/2885/163/11037/1759/23149/3312/29993/9185/7314/9856/1839/161/7018/25977/5868/10618/10093/8027/1856/9892/8322/2060/2069/1601/6453/55707/8301/1129/9146/6455/4074/26119/29979/6233/90019/7474/6844/1213/2580/1211/29924/4036/255324/1175/85021/10109/6869/1173/6857/84251/23048/9026/29988/409/112574/382/160/338/8218/920/22905/26052/8867/10092/9829/2873/10097/7311/1956/60/8533/274/51429/8673/3092/50618/51138/9318/685/127833/1080/29978/58513/7316/1950/273/10552/26130/3267/3949/867/9341/915/917/6572/115548/5878/1861/10096/143425/3575/6845/551/154/10254/6457/50813/4952/11252 139 Human_cytomegalovirus R-HSA-69242 S Phase 150/5218 161/10654 2.6359796607879683e-34 1.546441400995608e-32 5.9078316081695256e-33 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/10274/5925/143471/5705/5709/5422/9978/1869/4174/5753/5695/84515/4609/4998/5711/5928/5683/990/5699/5702/8900/51529/29945/51434/84296/6117/29882/5001/10714/7465/5696/5691/7314/996/5718/6118/7027/5700/122706/5707/64785/23198/898/91768/5934/5557/993/890/51433/9861/2932/6502/5698/10000/5692/5985/5713/119504/595/4175/5710/5984/7324/5719/64682/6233/7029/113130/23649/1163/5424/4172/1019/5000/8318/246184/54107/4173/5706/286826/23047/8881/5885/4331/5425/5714/5111/6119/5688/5687/91750/5427/5708/1874/8243/81620/10393/208/5704/55957/51343/7311/25906/5983/5694/4176/56655/1017/5684/994/5720/902/57804/207/5690/5717/1027/9491/6500/23244/10735/10197/4149/7316/10213/1875/1026/5426/4171/5715/5701/5685/5686/9126/5716/5981/1022/5693/5721/132660 150 Human_cytomegalovirus R-HSA-69620 Cell Cycle Checkpoints 241/5218 293/10654 4.7280785642433776e-33 2.6628538473818702e-31 1.0172834300329963e-31 5689/55839/11130/9134/83990/11065/6249/5682/9156/57060/9735/1763/7531/7486/7321/5526/10971/8697/9212/5982/7533/2810/147841/348995/11200/143471/472/57122/5705/1780/23122/5048/5709/4174/5695/57405/8655/84515/23279/4194/4998/5711/2491/4683/10926/5683/990/1060/84126/5699/5702/8900/51529/29945/8924/11004/51434/55388/672/9184/5518/6117/29882/7334/5001/23332/7465/25909/51230/10726/81930/55746/5696/83695/5691/7314/996/5515/5718/6118/79682/10403/25936/5700/122706/5707/51588/51720/3619/23198/63967/898/64105/7534/332/5528/993/116028/890/983/51433/9861/79902/3796/9656/5519/81565/5698/5692/5985/5713/91687/119504/4175/5710/7157/5984/7324/83540/5719/64682/6233/7514/7158/54820/6396/64946/9793/5884/5810/140735/220134/4172/80010/4928/5903/5000/8318/246184/55055/51512/1029/80776/1783/401541/7532/79172/4173/5706/9133/79980/6232/580/8881/11073/891/5501/641/5714/54821/6119/9183/3364/10524/5688/1062/699/5687/144715/5708/22919/5529/51143/1111/10393/5704/7311/25906/5347/84643/5983/5694/4176/7529/1778/5516/1017/5905/81929/5684/5720/54908/55143/5883/5525/25946/1058/991/79019/10111/8317/348235/80152/5690/1063/8379/5717/1027/9491/23421/545/55920/79023/10197/7336/29086/1781/7316/10213/4085/1026/4171/55166/5715/9088/7341/5701/5685/5686/995/79003/5527/5716/701/5932/79184/57551/7156/5693/5721/4193 241 Human_cytomegalovirus R-HSA-68877 Mitotic Prometaphase 177/5218 200/10654 7.711879422825432e-33 4.1762793182070035e-31 1.5954535971918205e-31 10844/55839/11130/440145/6249/9735/7531/1459/11190/203068/5526/54801/51807/9212/347688/10274/1460/147841/348995/79441/10381/57122/5116/1780/23122/5048/57405/8655/1457/23279/9702/2491/7846/7840/1060/11064/11004/9184/5518/55835/23332/25909/10726/81930/55746/93323/5515/79682/10403/64151/25936/55869/1454/3619/64105/332/10051/5528/983/79902/3796/79959/5519/81565/80097/91687/10376/23397/10540/83540/7514/54930/54820/113130/6396/1453/64946/9793/140735/220134/84617/4928/5903/11258/22981/55055/8636/80776/1783/401541/7532/55125/10382/79172/121441/7277/9133/79980/6232/23047/9814/5885/23354/891/5501/9738/1639/55722/4957/5566/54821/9183/1062/699/7283/22919/8243/10426/5529/22994/51143/1069/5577/10383/5347/84790/84643/80184/22897/5108/10592/7280/10806/1778/5516/115106/4926/5905/22995/55559/81929/54908/55143/5525/10142/1058/991/79019/348235/80152/1063/8379/95681/23244/23421/55920/79023/10735/1781/80321/4085/55166/10121/84131/3320/79003/9126/10733/4751/5527/80254/701/57551/9662/55142/8481/55755 177 Human_cytomegalovirus R-HSA-168273 Influenza Viral RNA Transcription and Replication 128/5218 134/10654 1.3249570292135243e-32 6.909405544935712e-31 2.6395830094663198e-31 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/116832/23225/6156/6143/5439/6139/9972/3921/8021/55746/6208/6170/6203/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/6188/6396/129401/200916/6122/6230/4928/2963/5434/5903/6194/55706/7175/6166/5436/6136/6125/6232/6160/5611/6193/4927/6210/6229/6205/2962/140801/6235/6181/8086/7311/6223/25873/9045/6187/5432/6168/6157/6137/6144/81929/5440/9349/4736/51121/9631/6159/6217/3843/5430/6152/51065/6141/79023/6123/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 128 Human_cytomegalovirus R-HSA-72613 Eukaryotic Translation Initiation 116/5218 119/10654 2.1777139553623904e-32 1.0573176721207743e-30 4.039244396334597e-31 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/116832/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/1978/200916/6122/1968/6230/8669/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/8893/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/8891/51121/6159/6217/6152/51065/6141/10480/6123/1967/6164/8661/9669/6209/1964/11224/6165/6130/8890/6204/6228/6124/3646/6189/6135/6201/6161/8892/6133 116 Human_cytomegalovirus R-HSA-72737 Cap-dependent Translation Initiation 116/5218 119/10654 2.1777139553623904e-32 1.0573176721207743e-30 4.039244396334597e-31 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/116832/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/1978/200916/6122/1968/6230/8669/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/8893/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/8891/51121/6159/6217/6152/51065/6141/10480/6123/1967/6164/8661/9669/6209/1964/11224/6165/6130/8890/6204/6228/6124/3646/6189/6135/6201/6161/8892/6133 116 Human_cytomegalovirus R-HSA-5683057 MAPK family signaling cascades 240/5218 294/10654 6.648073814104567e-32 3.120162643419743e-30 1.1919879715815558e-30 2308/5689/374/3725/2674/4893/6711/2250/1437/71/5682/1844/1848/5526/817/7039/27327/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/2668/5605/4609/5037/5711/3558/3717/2244/5683/145957/2534/3690/408/9965/5699/2264/5702/192669/4296/5894/9542/2885/6709/8660/8826/5518/2252/4140/4343/2253/3845/3265/4763/3569/5062/5696/5691/7314/3572/5879/5515/5923/5718/818/1839/3667/8823/2065/5700/3815/122706/5707/5567/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/3337/2260/5528/983/3718/2249/6714/9861/2248/5519/3567/2247/5698/5692/5713/2335/1445/5710/8555/896/5719/6233/2266/2246/7514/2251/5154/2243/1843/3570/255324/26523/369/801/200734/7297/5781/8682/4747/10602/28956/805/9462/3562/6464/6712/2904/5747/283455/3674/7010/5568/2322/3315/409/5706/1438/673/2263/4233/5597/84078/5714/5566/5688/5159/5687/5708/3084/5529/816/998/9693/9365/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/5058/7529/5595/25759/5516/8822/5786/27161/815/5684/685/5720/2309/5604/3561/5525/153090/10642/10048/5690/57690/5717/9491/3568/8817/10197/192670/5596/8550/2254/7316/10213/1950/3560/26281/10818/5715/2261/5701/27040/5685/2255/8649/53358/5686/2066/27006/8556/5979/23112/5527/5716/88/5906/5155/4254/399473/808/3559/8202/5693/5721/5245/5156/161742/284 240 Human_cytomegalovirus R-HSA-69206 G1/S Transition 125/5218 131/10654 1.0189687397296336e-31 4.628090275933304e-30 1.768057813249042e-30 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/4998/5711/5928/10926/5683/990/5699/5702/8900/55388/28227/5518/6117/5001/7465/5696/5691/7314/5515/6241/5718/6118/7027/5700/5707/898/91768/5934/5557/993/890/1876/983/9861/5519/6502/5698/10000/5692/5713/595/4175/5710/5719/6233/7298/7029/23649/1719/1163/4172/26271/1019/5000/8318/54107/4173/5706/286826/891/4331/5714/5111/51053/6119/5688/5687/91750/5427/5708/1874/81620/208/5704/55957/7311/5694/4176/5516/56655/1017/5684/5720/902/8317/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5933/5426/4171/5715/5701/5685/5686/3065/5716/1022/5693/5721/7083/132660 125 Human_cytomegalovirus R-HSA-927802 Nonsense-Mediated Decay (NMD) 112/5218 115/10654 3.5693253169362667e-31 1.5229121352261404e-29 5.817943339567567e-30 6158/9887/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/55629/6169/6175/6218/65109/6173/6167/116832/6156/6143/5520/6139/23381/5518/3921/6208/6170/5515/6203/6147/6222/26019/2935/6134/22794/6155/4116/6231/6142/23521/1981/6207/6233/6188/23049/5976/200916/6122/6230/6194/2107/6166/56006/6136/6125/6232/6160/55110/6193/6210/6229/6205/55181/140801/6235/6181/9939/7311/6223/25873/23708/9045/6187/65110/6168/22916/6157/6137/10921/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/4686/6209/11224/6165/6130/6204/6228/55802/6124/6189/23293/9775/6135/6201/6161/6133 112 Human_cytomegalovirus R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 112/5218 115/10654 3.5693253169362667e-31 1.5229121352261404e-29 5.817943339567567e-30 6158/9887/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/55629/6169/6175/6218/65109/6173/6167/116832/6156/6143/5520/6139/23381/5518/3921/6208/6170/5515/6203/6147/6222/26019/2935/6134/22794/6155/4116/6231/6142/23521/1981/6207/6233/6188/23049/5976/200916/6122/6230/6194/2107/6166/56006/6136/6125/6232/6160/55110/6193/6210/6229/6205/55181/140801/6235/6181/9939/7311/6223/25873/23708/9045/6187/65110/6168/22916/6157/6137/10921/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/4686/6209/11224/6165/6130/6204/6228/55802/6124/6189/23293/9775/6135/6201/6161/6133 112 Human_cytomegalovirus R-HSA-2262752 Cellular responses to stress 356/5218 479/10654 5.4086901936206095e-31 2.2398340566522996e-29 8.556782318700099e-30 1912/23165/5689/3725/6782/9134/2077/11065/573/4790/54468/5682/64344/7531/1915/11133/7321/51807/817/6045/8697/9530/347688/23677/27327/80012/7295/5925/3091/348995/143471/472/10381/57122/5705/79813/3576/3313/1780/7001/23511/10312/5709/9978/2114/1869/5695/3305/8655/84516/1911/832/26277/23279/4194/1031/5711/5928/1432/1387/4683/10325/7846/259217/23225/5683/3309/23512/57332/5699/126374/7428/5702/192669/9531/8900/51529/4001/29945/8091/8131/2056/51434/2475/3306/27000/1030/6196/9972/10670/23411/8021/4343/6117/6197/29882/3312/4217/54386/3569/64121/55746/5696/5691/7296/7314/51164/996/51182/5718/818/3303/7014/6118/51606/5601/5606/7027/526/5700/122706/5707/2146/9550/2936/5594/3308/84335/23198/898/10049/10013/27244/3337/10762/847/7323/890/5970/9261/6667/51433/9861/79902/5598/9883/2932/84733/529/5698/5692/5713/2877/119504/10376/6195/5710/3301/10540/7157/7324/5719/64682/6233/2353/538/7029/8726/6396/1535/129401/5600/523/201163/26523/405/5608/3297/57521/140735/768/6015/28956/84617/4928/4688/1019/5903/83667/55706/7175/5241/11258/9448/246184/112399/1029/1783/389541/25828/8535/84962/10382/93661/5931/58528/10294/55860/830/7013/7277/1051/1410/5706/10671/8881/527/6774/1639/5714/4927/7867/64223/6119/26353/3552/10370/10524/5688/57805/5687/3281/3310/2908/5708/5602/7266/25824/6009/51143/816/6648/8086/10393/1870/5704/3326/55004/51343/7311/367/25906/3397/2034/79400/57634/10383/84790/55662/648/5694/3304/23466/3456/2113/6416/7280/10728/829/23523/5595/1778/1017/815/25913/81929/5684/5720/9631/3159/7290/116835/10111/7422/5690/57690/5717/1027/9491/545/79023/23636/10197/192670/10808/153129/3490/8550/29855/4306/1781/7316/10213/10935/53371/1026/9532/54205/2289/9588/9688/10121/7415/1871/6647/8994/7322/5715/5701/5685/8649/3320/65057/5686/2033/1021/6767/25842/8453/50507/23135/10963/22824/57600/23112/5609/10542/5716/9529/5599/54583/5052/1536/96459/5693/5721/55466/2288/5034/8480/10919/51382/4193/2950/9296/23043 356 Human_cytomegalovirus R-HSA-373076 Class A/1 (Rhodopsin-like receptors) 265/5218 335/10654 9.167323334077721e-31 3.687883215537552e-29 1.4088728492372077e-29 729230/2532/10316/2149/23620/1880/7852/10161/338442/64805/1237/5734/3354/2841/4987/51289/2150/3060/3576/6360/2798/5737/338557/4985/2920/3061/2921/1236/6010/554/2840/2831/5367/5028/4988/6370/58191/6755/6866/1524/94233/643/5029/2867/185/339403/8843/64106/2847/2833/6347/9290/9170/187/6750/2587/53829/8111/6387/4544/4543/2922/10663/4889/9283/727/1909/5732/117579/3579/6375/2492/23566/2358/1131/6846/5179/27334/5021/6865/2797/8811/56923/2832/2693/27199/2826/6376/165140/27198/7201/5443/6354/3627/3361/6346/553/257313/134/3814/10800/2863/1129/51083/2829/1233/6366/1241/2861/728/183/10022/6373/57121/4922/5731/2865/1132/1814/6357/552/2925/8698/9934/2151/6869/2147/1813/50865/10886/2837/10803/146/3357/351/11251/8477/84432/3352/8484/2828/3062/1907/148/6351/6863/6752/1903/84539/6753/3577/594857/5368/6754/6915/8862/10911/301/5032/56670/150/2853/29933/6751/5020/4935/887/4829/186/53637/60675/51738/10563/5540/2864/1901/5733/256933/7200/5729/10850/624/2796/4852/4828/680/5473/4283/1910/6870/128674/11255/885/10874/84634/147/6356/56477/387129/3350/129521/1234/151/57007/3356/84109/9294/4923/1128/283869/4986/6374/5539/2852/1230/3358/4886/2919/1908/5196/3827/5173/2357/6352/57105/1133/140/3269/6348/886/2862/152/1906/6364/5031/8620/5030/5697/56413/3355/3351/6288/6372/5739/719/6363/1268/2359/347148/2846/5660/1815/1325/1232/4295/1902/551/154/9002/1269/59340/5724/4887/718/623 265 Human_cytomegalovirus R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 109/5218 112/10654 2.8975826033386064e-30 1.1332767515279884e-28 4.3294289775030057e-29 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/6202/6169/6175/6218/6173/6167/116832/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/200916/6122/1968/6230/8669/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/9669/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 109 Human_cytomegalovirus R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 108/5218 111/10654 5.819595447474005e-30 2.214591997309027e-28 8.460350707423092e-29 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/116832/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/200916/6122/1968/6230/8669/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 108 Human_cytomegalovirus R-HSA-9607240 FLT3 Signaling 218/5218 267/10654 4.3898031211919484e-29 1.6265375775363853e-27 6.213821038584726e-28 5295/5689/374/2674/4893/6711/2250/1437/71/5682/1844/5291/1848/5526/817/7039/5908/3082/143471/2064/5705/8452/6776/4684/5709/9978/5695/2668/5605/5037/5711/3558/3717/2244/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/9542/2885/6709/8660/8826/9846/5518/2252/4140/2253/3845/3265/4763/5696/5691/7314/5515/54106/5923/5718/818/1839/5290/3667/8823/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/2260/5528/3718/2249/6714/9861/2248/5519/3567/2247/5698/5692/5713/2335/1445/5710/5719/6233/2266/2246/2251/5154/2243/1843/6777/255324/369/801/200734/5781/30849/8682/4747/28956/805/5170/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/409/5706/1438/673/2263/4233/84078/5714/5688/5159/5687/5708/3084/5529/816/9693/208/9365/6654/5704/10718/3716/7311/7450/1956/60/5536/2549/5694/7529/5595/25759/5516/8822/5786/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10197/2254/7316/10213/1950/3560/5289/3055/26281/10818/5715/2261/5701/27040/5685/2255/8649/53358/5686/2066/27006/5979/5527/5716/88/5906/5155/4254/5296/399473/808/3559/5693/5721/5245/5156/161742/284 218 Human_cytomegalovirus R-HSA-8957275 Post-translational protein phosphorylation 105/5218 108/10654 4.704990808523818e-29 1.6986223226670605e-27 6.489204596911393e-28 56955/4240/3270/9210/10272/2153/7857/29106/91851/6696/51156/1435/265/11098/10130/2200/80341/375056/1114/720/10117/3956/3569/54972/2519/8720/7018/10618/11167/813/5179/8074/51246/348/4924/3484/102/8614/336/6694/4148/174/57104/2335/7466/116519/2266/51280/7076/2243/84141/3488/8542/4221/351/4052/7184/56975/334/3912/338/64856/335/5611/197/3053/3895/5624/1000/54757/8404/255738/3913/652/57719/147111/2719/3487/3371/54587/401138/3486/7425/6383/3827/3490/5589/2621/3915/5768/1471/1462/10232/462/3698/5265/1758/258/11320/5954/213/10970/5034/1356/718 105 Human_cytomegalovirus R-HSA-8953897 Cellular responses to external stimuli 360/5218 493/10654 9.018986724502966e-29 3.1746833270250444e-27 1.2128163726897412e-27 1912/23165/5689/3725/6782/9134/2077/11065/573/4790/54468/5682/64344/7531/1915/11133/7321/51807/817/6045/8697/9530/347688/23677/27327/80012/7295/5925/3091/348995/143471/472/10381/57122/5705/79813/3576/3313/1780/7001/23511/10312/5709/9978/2114/1869/5695/3305/8655/84516/1911/832/26277/23279/4194/1031/5711/5928/1432/1387/4683/10325/7846/259217/23225/5683/3309/23512/57332/5699/126374/7428/5702/192669/9531/8900/51529/4001/29945/8091/8131/2056/51434/2475/3306/27000/1030/6196/9972/10670/23411/8021/4343/6117/6197/29882/3312/4217/54386/3569/64121/55746/5696/5691/7296/7314/51164/996/51182/6620/5718/818/3303/7014/6118/51606/5601/5606/7027/526/5700/122706/5707/2146/9550/2936/5594/3308/84335/23198/898/10049/10013/27244/3337/10762/847/7323/1465/890/5970/9261/6667/51433/9861/79902/5598/9883/2932/84733/529/5698/5692/5713/2877/119504/10376/6195/5710/3301/10540/7157/7324/5719/64682/6233/2353/538/7029/8726/6396/1535/129401/5600/523/201163/26523/405/5608/3297/57521/140735/768/6015/28956/84617/4928/4688/1019/5903/83667/55706/7175/5241/11258/9448/246184/112399/1029/1783/389541/25828/8535/84962/10382/93661/5931/58528/10294/55860/830/7013/7277/1051/1410/5706/10671/8881/527/6774/1639/5714/4927/7867/64223/6119/26353/3552/10370/10524/5688/57805/5687/3281/3310/2908/5708/5602/7266/25824/6009/51143/816/6648/8086/10393/1870/5704/3326/55004/51343/7311/367/25906/3397/2034/79400/57634/10383/84790/55662/648/5694/3304/23466/3456/2113/6416/7280/10728/829/23523/5595/1778/1017/815/25913/81929/5684/5720/9631/3159/7290/116835/10111/4502/7422/5690/57690/5717/1027/9491/545/79023/23636/10197/192670/10808/153129/3490/8550/29855/4306/1781/7316/10213/10935/53371/1026/9532/54205/2289/9588/9688/10121/7415/1871/6647/8994/7322/5715/5701/5685/8649/3320/65057/5686/2033/1021/6767/25842/8453/50507/23135/10963/22824/57600/23112/5609/10542/5716/9529/4520/5599/54583/5052/1536/96459/5693/5721/55466/2288/5034/8480/10919/51382/4193/2950/9296/23043 360 Human_cytomegalovirus R-HSA-162909 Host Interactions of HIV factors 121/5218 129/10654 1.225193031595999e-28 4.20749216704187e-27 1.6073777641734419e-27 23165/5689/162/5682/1174/348995/143471/57122/5705/23511/5709/9978/5695/292/567/23279/5711/23225/5683/2534/5699/5702/3836/163/9972/8021/1794/904/5062/55746/5696/5691/7314/5879/5718/8945/51606/161/5700/122706/5707/10053/23198/10762/926/9861/79902/9883/5698/5692/5713/5710/5902/5478/5719/6233/7514/1025/3932/6396/129401/1175/8907/940/60489/1173/4928/5903/55706/7175/4869/5706/160/920/5714/4927/5688/5687/5708/5901/8086/5704/7311/8905/5694/1104/5905/3837/81929/164/5684/8065/5720/9631/3159/5690/5717/9491/6500/79023/23636/10197/919/130340/7316/10213/53371/3055/9688/5715/5701/5685/8815/5686/5716/9844/375/5693/5721/8480/291 121 Human_cytomegalovirus R-HSA-5684996 MAPK1/MAPK3 signaling 209/5218 255/10654 2.290573052936682e-28 7.67887347270202e-27 2.933540927445224e-27 5689/374/2674/4893/6711/2250/1437/71/5682/1844/1848/5526/817/7039/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/2668/5605/5037/5711/3558/3717/2244/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/9542/2885/6709/8660/8826/5518/2252/4140/2253/3845/3265/4763/3569/5696/5691/7314/3572/5515/5923/5718/818/1839/3667/8823/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/2260/5528/983/3718/2249/6714/9861/2248/5519/3567/2247/5698/5692/5713/2335/1445/5710/5719/6233/2266/2246/2251/5154/2243/1843/3570/255324/369/801/200734/7297/5781/8682/4747/28956/805/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/409/5706/1438/673/2263/4233/84078/5714/5688/5159/5687/5708/3084/5529/816/9693/9365/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/7529/5595/25759/5516/8822/5786/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10197/2254/7316/10213/1950/3560/26281/10818/5715/2261/5701/27040/5685/2255/8649/53358/5686/2066/27006/5979/5527/5716/88/5906/5155/4254/399473/808/3559/5693/5721/5245/5156/161742/284 209 Human_cytomegalovirus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 151/5218 171/10654 6.325457150579418e-28 2.071219457678098e-26 7.912628161434719e-27 6158/5689/6138/6227/6206/6234/6191/6128/5682/6132/6129/6176/6224/6146/6154/26986/143471/6202/5705/6169/5709/6175/9978/6218/5695/65109/6173/6167/5711/116832/5683/6156/5699/6143/5702/6139/3921/6208/5696/6170/5691/7314/5718/6203/6147/5700/122706/5707/6222/23198/26019/2935/6134/22794/6155/4116/6231/9861/6142/23521/5698/5692/5713/1981/5710/6207/5719/6233/6188/200916/6122/6230/1287/6194/2107/6166/6136/6125/5706/6232/6160/55110/5714/6193/6210/6229/6205/5688/5687/5708/140801/6235/6181/9939/5704/7311/6223/25873/23708/5694/9045/6187/65110/6168/22916/6157/6137/10921/6144/23032/5684/9349/4736/5720/51121/6159/6217/6152/5690/5717/9491/51065/6141/23053/6123/10197/6164/4686/7316/10213/6209/11224/6165/6130/5715/6204/5701/6228/5685/5686/6124/8453/5716/6189/9775/6135/6201/6161/5693/5721/6133 151 Human_cytomegalovirus R-HSA-376176 Signaling by ROBO receptors 183/5218 218/10654 1.6727491983547396e-27 5.301568353039546e-26 2.0253449674067053e-26 6158/5689/6138/6227/7852/6206/6234/6191/6128/5682/6132/10298/6129/6176/5578/6224/6146/6154/26986/143471/6202/5705/6169/23122/5709/6175/9978/6218/5695/65109/6173/6167/5711/116832/5683/6156/5699/6143/5702/6139/8440/3921/23332/5062/6208/5696/6170/5691/7314/5879/6387/5718/25/6203/6147/5700/122706/5707/5567/6222/23198/27/26019/2935/6134/22794/6155/4116/6714/6231/9861/6142/23521/10486/5698/5692/5713/1981/5710/6207/5719/6233/6188/200916/6122/6230/1287/6194/2107/6166/6136/5568/6125/5706/6232/6160/55110/5714/6193/6210/6229/6205/5566/4650/5688/5687/5708/140801/6235/6181/998/9939/6654/5704/7311/6223/25873/387/6655/23708/5694/5058/9045/6187/65110/6168/22916/6157/6137/10921/6144/55740/23032/5684/9349/4736/5720/51121/2817/6159/4690/6217/6152/5690/5532/5717/9491/51065/6141/23053/6123/10197/6164/4686/7316/10213/5216/6209/11224/6165/6130/5715/6204/5701/6228/5576/5685/51466/5686/7408/6124/8453/5716/23380/1630/6189/9775/6135/6201/6161/5693/5721/6133 183 Human_cytomegalovirus R-HSA-418594 G alpha (i) signalling events 304/5218 406/10654 1.6943932946504234e-27 5.301568353039546e-26 2.0253449674067053e-26 729230/2788/10316/6000/1880/7852/50833/29899/2339/6385/5726/338442/64805/2770/817/1237/1258/2550/5578/50832/3354/2841/5582/4987/51289/259294/2912/3576/6360/2775/5530/4985/2920/2921/1236/259295/107/6010/9568/2840/2831/5367/4988/6370/58191/5475/6755/1524/643/2782/5996/5499/339403/4023/2914/8843/2847/2833/10636/9290/5518/9170/6382/187/6750/6004/259296/259289/5998/50835/2587/53829/2773/5515/2787/6387/818/4544/4543/126006/10663/4889/9283/727/338398/344/117579/3579/345/375790/23566/2358/5567/2916/259293/5594/5179/10681/5142/112/8811/5573/348/56923/2832/5528/27199/2826/6376/165140/27198/111/5443/8630/4836/3627/2792/9397/54429/6714/336/3361/6346/10988/5519/134/5588/6295/1129/338328/51083/2785/2783/2784/1233/6366/5613/2861/2771/728/183/10022/5580/6373/57121/3710/1132/1814/80835/4036/6357/196883/9672/115/8698/5999/801/9934/50840/2791/50865/805/10803/2913/3838/7276/351/11251/3352/8484/6351/6752/2781/1903/84539/6753/5568/3577/2918/5368/6754/8862/301/56670/150/113/338/335/2853/6751/186/53637/5566/10563/5540/1901/5148/5733/256933/10850/624/4852/816/2786/50838/5577/5473/4283/11255/10874/83756/51109/2719/56477/1020/5950/259286/3350/129521/1234/109/5516/151/57007/815/26086/5321/9294/54331/283869/2817/5575/59345/63940/4986/6374/5539/259287/2852/50836/1230/5532/846/4886/2919/51764/94235/114/3708/259290/57016/6383/108/5196/3827/5173/2357/55970/2778/6352/140/10768/346562/152/5957/6364/80834/259292/3949/2793/5030/5697/5576/3355/5534/3351/4035/6288/6372/50834/259285/1385/7804/719/6363/2917/1268/50831/2359/50839/808/5660/1815/1325/1232/1902/50837/5137/1269/59340/4887/2790/718/623 304 Human_cytomegalovirus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 91/5218 92/10654 1.965675563794838e-27 6.016676508311157e-26 2.2985359567486557e-26 6884/6875/5563/83990/9156/1763/1459/7486/6874/9212/5982/1460/11200/472/53632/28996/1457/6790/4194/1432/4683/84126/8900/6873/672/6881/51616/6117/11198/83695/7314/1263/6118/51422/116028/890/83860/5985/7157/5984/6233/5600/6883/5884/5810/26155/80010/8445/204851/6878/580/11073/641/8148/6119/3364/5571/10524/54457/144715/6794/94241/1111/7311/5562/6880/6908/5983/5564/6882/5565/1020/6877/1017/9891/5883/10111/22974/6749/545/8550/7316/6872/6879/112858/5932/8851/5300/7156/138474/4193 91 Human_cytomegalovirus R-HSA-416476 G alpha (q) signalling events 182/5218 217/10654 2.913641021668032e-27 8.728524592571467e-26 3.3345365331967847e-26 5295/2788/10316/2149/23620/4893/10161/5578/1608/2150/3060/2769/2798/5737/338557/3061/2911/2840/5367/5028/6866/94233/5029/2782/5996/2867/2776/185/2885/6196/64106/2847/9170/6197/3845/6004/3265/5998/8111/2787/2922/1839/5290/1909/6375/23566/2358/7225/1131/6846/5594/27334/10681/5021/6865/2797/56923/2693/7201/2792/553/257313/5598/3814/10800/5588/2863/2785/6195/2783/2784/2829/222545/8525/1241/183/5580/57121/4922/5731/2865/3710/552/2925/5999/2151/6869/2791/2147/10886/2520/2837/146/3357/351/8477/84432/2828/3062/1907/148/6863/84539/594857/6915/10911/301/5032/2642/29933/5020/4935/887/4829/60675/51738/8503/2864/7200/624/2641/2796/4828/695/2786/680/6654/1910/6870/128674/885/1956/10874/84634/147/387129/129521/5595/3356/84109/54331/4923/1128/59345/1606/846/3358/1908/51764/94235/3708/3827/55970/57105/1133/4314/3269/2767/886/2862/1906/5031/8620/2793/56413/6288/2869/1385/5997/5296/5581/347148/2846/9630/4295/1902/551/9002/2915/5724/2790/623 182 Human_cytomegalovirus R-HSA-375276 Peptide ligand-binding receptors 171/5218 201/10654 3.526075287712365e-27 1.0343154177289604e-25 3.9513694561864446e-26 729230/2532/10316/2149/23620/7852/1237/4987/51289/2150/3060/3576/6360/4985/2920/3061/2921/1236/554/2831/5367/4988/6370/58191/6755/6866/1524/643/185/339403/64106/2847/2833/6347/187/6750/2587/6387/2922/10663/4889/9283/727/1909/117579/3579/6375/2358/6846/5179/5021/6865/8811/56923/2832/2693/2826/6376/7201/5443/6354/3627/6346/553/257313/3814/51083/2829/1233/6366/2861/728/183/10022/6373/4922/6357/552/2925/2151/6869/2147/50865/10886/2837/10803/351/84432/8484/3062/1907/6351/6863/6752/84539/6753/3577/594857/5368/6754/8862/10911/301/6751/5020/887/4829/186/60675/51738/10563/5540/256933/7200/10850/624/4852/4828/680/5473/4283/1910/6870/128674/885/10874/84634/6356/56477/387129/129521/1234/57007/84109/4923/283869/4986/6374/5539/2852/1230/4886/2919/1908/5196/3827/5173/2357/6352/6348/886/2862/1906/6364/8620/5697/6288/6372/719/6363/2359/347148/5660/1325/1232/4295/551/9002/4887/718/623 171 Human_cytomegalovirus R-HSA-5673001 RAF/MAP kinase cascade 203/5218 249/10654 5.517204785783556e-27 1.5853519057924994e-25 6.056480441536837e-26 5689/374/2674/4893/6711/2250/1437/71/5682/1844/1848/5526/817/7039/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/2668/5605/5037/5711/3558/3717/2244/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/9542/2885/6709/8660/8826/5518/2252/4140/2253/3845/3265/4763/5696/5691/7314/5515/5923/5718/818/1839/3667/8823/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/2260/5528/3718/2249/6714/9861/2248/5519/3567/2247/5698/5692/5713/2335/1445/5710/5719/6233/2266/2246/2251/5154/2243/1843/255324/369/801/200734/8682/4747/28956/805/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/409/5706/1438/673/2263/4233/84078/5714/5688/5159/5687/5708/3084/5529/816/9693/9365/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/7529/5595/25759/5516/8822/5786/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10197/2254/7316/10213/1950/3560/26281/10818/5715/2261/5701/27040/5685/2255/8649/53358/5686/2066/27006/5979/5527/5716/88/5906/5155/4254/399473/808/3559/5693/5721/5245/5156/161742/284 203 Human_cytomegalovirus R-HSA-72689 Formation of a pool of free 40S subunits 98/5218 101/10654 6.09400962673367e-27 1.7160731108882015e-25 6.555871408970328e-26 6158/6138/6227/6206/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/8663/23521/6207/6233/51386/6188/200916/6122/6230/8669/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/8664/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 98 Human_cytomegalovirus R-HSA-69306 DNA Replication 118/5218 127/10654 6.528190273291417e-27 1.8022925303518266e-25 6.885253311975056e-26 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/143471/5705/5709/5422/9978/1869/4174/5695/84515/4998/5711/10926/5683/990/5699/5702/8900/51529/29945/51434/55388/84296/6117/29882/5001/10714/5696/5691/7314/996/5718/6118/5700/122706/5707/64785/23198/898/5557/890/51433/9861/6502/5698/5692/5985/5713/119504/4175/5710/5984/7324/5719/64682/6233/23649/5424/4172/5000/8318/246184/54107/4173/5706/8881/5425/5714/5111/51053/6119/5688/5687/5427/5708/81620/10393/1870/5704/51343/7311/25906/5983/5694/4176/56655/1017/5684/5720/57804/8317/5690/5717/9491/6500/10197/7316/10213/5426/4171/1871/5715/5701/5685/5686/5716/5981/5693/5721 118 Human_cytomegalovirus R-HSA-68886 M Phase 295/5218 395/10654 2.199010223633827e-26 5.954243067070054e-25 2.2746846645281085e-25 10844/23165/5689/55839/11130/11065/440145/6249/5579/5682/9735/7531/1459/11190/7321/91754/203068/5526/54801/51807/8697/5578/9212/347688/10274/5861/5925/1460/147841/348995/79441/143471/10381/57122/5705/5116/1780/23122/23511/5048/5709/5695/57405/8655/1457/23279/9702/5711/2491/10112/7846/23225/7840/5683/1060/5699/11064/5702/5520/51529/4001/29945/11004/51434/9184/9972/5518/55844/55835/8021/29882/23332/84930/25909/10726/81930/55746/93323/5696/5691/7314/996/5515/5718/79682/10403/64151/25936/55869/5700/122706/5707/1454/2801/5594/3619/23198/64105/23310/332/10762/10051/5528/983/8548/51433/9861/79902/3796/8615/79959/5519/9883/81565/7444/5698/5692/5713/80097/91687/119504/10376/23397/5710/10540/7324/83540/2010/64900/5719/64682/6233/23175/7514/54930/54820/113130/9493/6396/129401/1453/64946/9793/140735/220134/84617/4928/26271/5903/55706/7175/11258/22981/246184/55055/8636/80776/1783/401541/7532/55125/10382/79172/121441/7277/5706/9133/79980/6232/23047/8881/9814/5885/23354/891/5501/9738/1639/5714/55722/4957/4927/5566/54821/81876/9183/5688/1062/699/5687/7283/5708/22919/8243/10426/5529/22994/51143/1069/8086/10393/79648/5577/5704/7311/25906/10383/5347/54892/84790/84643/80184/5694/22897/6418/5108/7112/10592/7280/10806/29781/5595/1778/5516/4000/115106/4926/5905/22995/55559/81929/5684/5720/54908/55143/9631/5525/10142/1058/991/79019/5862/348235/80152/5690/1063/8379/95681/5717/9491/23244/23421/55920/79023/23636/10735/10197/7443/1781/7316/10213/80321/53371/26003/4085/9688/55166/10121/5715/84131/5701/5685/3320/8815/5686/79003/9126/10733/23399/4751/9232/9700/5527/80254/5716/701/57551/9662/55142/64689/8481/5693/5721/55755/8480 295 Human_cytomegalovirus R-HSA-5357801 Programmed Cell Death 156/5218 181/10654 3.3596786777476944e-26 8.825008488434114e-25 3.371396035877567e-25 5689/2339/5682/4976/7531/356/10971/10059/7533/2810/143471/5705/5709/1869/5695/8655/660/5711/836/5683/929/324/5699/9414/5702/90427/4001/3836/6709/840/7159/26060/637/5062/5696/5691/7314/578/23368/5718/2934/11035/22985/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/100506658/7082/5339/4836/8797/9861/28988/10134/999/5588/598/5698/10000/5692/708/5713/5710/3002/7157/5719/6233/5580/1613/839/7029/8772/331/8717/57099/317/8743/140735/1828/5747/1029/572/7532/330/118/5706/1829/6774/5366/5714/8428/5688/5687/56616/5708/8837/8626/197259/208/5704/7311/7161/5694/8795/3148/7529/5595/23643/4000/27113/3837/596/5684/5720/7186/51765/1499/10018/842/207/5690/5717/9491/355/10197/7099/7316/10213/54205/3146/5715/23604/5701/329/5685/5686/5534/4137/5716/1630/581/5599/353376/7431/5693/5721/6304/148022 156 Human_cytomegalovirus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 87/5218 88/10654 3.38459132368922e-26 8.825008488434114e-25 3.371396035877567e-25 5393/5689/5682/23404/5578/26986/143471/5705/5709/5695/5711/1432/5683/5699/5702/11340/8021/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/7534/9261/8741/9861/5698/5692/5713/1981/5710/5719/6233/5580/7514/5600/8570/23016/118460/1994/5073/3842/3315/5706/8125/677/7538/5714/5688/5687/5708/5704/7311/51010/5694/56915/3304/6418/167227/7529/22894/5684/5720/207/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/55802/51013/5716/54464/5693/54512/5721 87 Human_cytomegalovirus R-HSA-500792 GPCR ligand binding 339/5218 468/10654 4.5911019433726795e-26 1.175322097503406e-24 4.490053766628592e-25 729230/2788/2532/10316/2149/23620/1880/7852/2692/10161/50833/5726/338442/64805/1237/5734/2550/50832/3354/2841/4987/51289/259294/2150/3060/2912/3576/6360/2798/5737/338557/4985/2920/3061/2921/1236/259295/6010/9568/554/2911/2840/2831/5367/3549/5028/5741/4988/6370/58191/6755/6866/1524/94233/643/5029/2782/2867/185/339403/2914/8843/64106/2847/2833/6347/9290/9170/6469/187/6750/259296/259289/50835/2587/53829/8111/2787/6387/4544/4543/2922/10663/4889/9283/727/1909/5732/338398/117579/3579/6375/2492/23566/2358/2916/259293/1131/8322/6846/5179/27334/10681/5021/6865/7471/2797/8811/56923/2832/2693/27199/2826/5727/6376/165140/27198/7201/89780/5443/6354/3627/2792/54429/50846/3361/6346/553/257313/134/3814/10800/5744/2863/1129/51083/2785/2783/2784/2829/1233/222545/6366/1241/2861/728/7474/183/10022/6373/57121/4922/5731/2865/7855/1132/1814/80835/6357/552/2925/8698/9934/2151/6869/50840/2791/2147/1813/50865/10886/2837/10803/146/2913/3357/351/11251/8477/84432/3352/8484/2828/3062/1907/148/6351/6863/6752/1903/84539/6753/3577/594857/2918/5368/6754/6915/8862/10911/301/5032/2642/56670/150/2853/29933/6751/5020/4935/887/4829/186/53637/60675/51738/10563/5540/2864/1901/5733/256933/7200/5729/10850/624/2641/1392/2796/4852/4828/2786/680/50838/5473/4283/1910/6870/128674/11255/885/10874/83756/84634/147/6356/56477/387129/259286/3350/129521/1234/151/57007/3356/84109/9294/54331/4923/1128/283869/59345/4986/6608/6374/5539/259287/2852/50836/1230/846/3358/4886/2919/1908/51764/94235/259290/5196/3827/5173/2357/55970/2778/6352/57105/1133/140/3269/6348/886/2862/152/2691/1906/6364/80834/259292/5031/8620/2793/5030/5697/56413/3355/3351/6288/6372/5739/50834/259285/719/6363/2917/1268/50831/2359/50839/347148/2846/5660/1815/1325/1232/4295/1902/551/154/50837/9002/1269/2915/59340/5724/4887/1394/2790/718/623 339 Human_cytomegalovirus R-HSA-5620912 Anchoring of the basal body to the plasma membrane 95/5218 98/10654 4.8715826725001167e-26 1.2248550719428864e-24 4.679283356480376e-25 79867/7531/11190/203068/54801/85302/79441/5116/5048/22832/8655/9702/132320/7846/7840/11064/84902/5518/55835/23332/93323/1454/54806/91147/983/79959/10540/117177/57545/26005/54930/54820/23322/1453/9793/4218/11258/22981/8636/54903/80776/7532/55125/10382/121441/7277/9814/23354/146057/9738/1639/55722/4957/5566/7283/22919/27077/22994/4867/1069/5577/10383/5347/80184/22897/5108/261734/57787/10806/9657/1778/115106/22995/55559/10142/51134/95681/1781/80321/8766/79598/10121/347240/84131/3320/79600/10733/4751/80254/26123/9662/55142/8481/51259/55755 95 Human_cytomegalovirus R-HSA-76002 Platelet activation, signaling and aggregation 210/5218 262/10654 5.606906492754782e-26 1.3850042704910058e-24 5.291097355120395e-25 5295/2788/2149/5777/5579/2153/5770/5291/7042/64805/2770/5175/5578/1608/5582/5908/3082/388/29106/2769/5267/7423/5028/1432/3920/374354/2244/7114/3309/2534/3690/408/2162/2782/87/2776/5894/2885/7040/9564/5874/54863/350/7043/2773/5879/5054/2787/5099/10411/1072/5290/7018/6678/5340/7225/5336/813/7094/5594/10681/7414/10490/83706/7044/7534/6810/7123/2792/6714/6694/3671/7273/22927/1191/3273/146850/27154/226/5588/5880/2335/5294/1/2785/2783/2784/1445/8525/5478/2771/94121/22915/7410/5580/2266/7409/5154/3932/7076/2243/3710/801/5781/2151/2791/2147/805/5170/5590/351/6464/135228/5747/51097/3937/7424/2316/3674/5552/409/6915/2157/7277/10451/334/1277/10447/150/335/308/6850/78991/8503/6403/197/4067/81/9948/998/3481/2786/6654/5473/8407/7450/387/29789/10916/5595/139322/7066/151/5321/54331/5005/59345/1606/207/7422/5004/51764/94235/3708/5196/3827/1950/55970/2621/5216/2767/5768/346562/710/152/6647/27040/2793/23533/1893/5265/7078/55664/391/5345/54676/2/1398/948/88/1675/2811/5906/3479/5155/5296/5581/51368/808/213/5660/9630/7057/1278/9002/2207/5627/6814/2790/3700 210 Human_cytomegalovirus R-HSA-69239 Synthesis of DNA 111/5218 119/10654 8.888492295131697e-26 2.157758129576798e-24 8.243229696574042e-25 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/143471/5705/5709/5422/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/84296/6117/29882/5001/10714/5696/5691/7314/996/5718/6118/5700/122706/5707/64785/23198/898/5557/890/51433/9861/6502/5698/5692/5985/5713/119504/4175/5710/5984/7324/5719/64682/6233/23649/5424/4172/5000/8318/246184/54107/4173/5706/8881/5425/5714/5111/6119/5688/5687/5427/5708/81620/10393/5704/51343/7311/25906/5983/5694/4176/56655/1017/5684/5720/57804/5690/5717/9491/6500/10197/7316/10213/5426/4171/5715/5701/5685/5686/5716/5981/5693/5721 111 Human_cytomegalovirus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 85/5218 86/10654 1.402547642844928e-25 3.2913118018760976e-24 1.2573716587609796e-24 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 85 Human_cytomegalovirus R-HSA-453276 Regulation of mitotic cell cycle 85/5218 86/10654 1.402547642844928e-25 3.2913118018760976e-24 1.2573716587609796e-24 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 85 Human_cytomegalovirus R-HSA-2219528 PI3K/AKT Signaling in Cancer 97/5218 101/10654 1.6001531853946526e-25 3.6934683361240506e-24 1.411006518958874e-24 5295/2308/374/2250/5291/7039/3082/941/2064/145957/2534/9965/2264/9542/2885/2475/8660/2252/2253/5879/1839/5290/3667/8823/2065/3815/2069/84335/8074/7249/2260/2249/6714/2099/2248/2932/2247/5880/10000/7409/2246/2251/5154/3932/2931/255324/5781/940/253260/5170/572/4303/930/6199/2263/4233/64223/8503/5159/3084/208/9365/10718/79109/5293/1956/2549/1147/8822/685/2309/842/207/1027/8817/2100/2254/1950/1026/55615/50852/26281/10818/2261/2255/3164/391/5728/2066/27006/942/1385/5155/4254/5296/5156/4193 97 Human_cytomegalovirus R-HSA-109581 Apoptosis 153/5218 178/10654 1.905244373184633e-25 4.3267485120063924e-24 1.6529369689258873e-24 5689/2339/5682/4976/7531/356/10971/10059/7533/2810/143471/5705/5709/1869/5695/8655/660/5711/836/5683/929/324/5699/9414/5702/90427/4001/3836/6709/840/7159/26060/637/5062/5696/5691/7314/578/23368/5718/2934/22985/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/100506658/7082/5339/4836/8797/9861/28988/10134/999/5588/598/5698/10000/5692/708/5713/5710/3002/7157/5719/6233/5580/1613/839/7029/8772/331/8717/57099/317/8743/140735/1828/5747/1029/572/7532/118/5706/1829/6774/5366/5714/8428/5688/5687/56616/5708/8837/8626/208/5704/7311/7161/5694/8795/3148/7529/5595/23643/4000/27113/3837/596/5684/5720/7186/51765/1499/10018/842/207/5690/5717/9491/355/10197/7099/7316/10213/54205/3146/5715/23604/5701/329/5685/5686/5534/4137/5716/1630/581/5599/353376/7431/5693/5721/6304/148022 153 Human_cytomegalovirus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 84/5218 85/10654 2.8541220902393776e-25 6.378736354058799e-24 2.436852778800872e-24 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/91768/5934/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/7029/1163/1019/5706/286826/4331/5714/5688/5687/91750/5708/1874/208/5704/55957/51343/7311/5694/1017/5684/994/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5715/5701/5685/5686/5716/1022/5693/5721/132660 84 Human_cytomegalovirus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 92/5218 95/10654 3.8799229061541016e-25 8.423902850677525e-24 3.2181626470515967e-24 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/2935/6134/6155/6231/6142/23521/1981/6207/6233/6188/5976/200916/6122/6230/6194/2107/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/23708/9045/6187/6168/22916/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/4686/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 92 Human_cytomegalovirus R-HSA-8876198 RAB GEFs exchange GTP for GDP on RABs 88/5218 90/10654 3.8888756057815274e-25 8.423902850677525e-24 3.2181626470515967e-24 5869/163486/116442/126003/7531/22878/1122/54453/10981/5861/163259/5866/23011/9610/60684/3257/414918/51762/51552/126432/201475/5874/79961/2665/79090/22898/58485/5868/81846/51622/84079/51209/5872/9827/80006/5870/8408/9909/10000/51112/117177/83696/1121/23682/27095/6399/7109/4218/7879/2664/201627/27342/23258/5864/10260/57679/81876/259173/6305/51693/8567/208/79890/22879/54734/57589/84315/22931/51399/10890/207/122553/79958/57706/22930/55667/26130/27147/25782/9367/51560/11021/5873/5878/11031/338382/89781/160518 88 Human_cytomegalovirus R-HSA-69618 Mitotic Spindle Checkpoint 105/5218 112/10654 6.098183268196335e-25 1.3009457638818847e-23 4.969970733729389e-24 55839/11130/11065/6249/9735/7321/5526/8697/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/996/5515/79682/10403/25936/3619/64105/332/5528/51433/79902/3796/5519/81565/91687/119504/7324/83540/64682/7514/54820/6396/64946/9793/140735/220134/4928/5903/246184/55055/80776/1783/401541/79172/79980/6232/8881/5501/54821/9183/1062/699/22919/5529/51143/10393/25906/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/55166/79003/5527/701/57551 105 Human_cytomegalovirus R-HSA-202403 TCR signaling 110/5218 119/10654 1.1762696600519215e-24 2.4455015377235692e-23 9.342488679551015e-24 5295/8454/5689/5335/4790/5682/5291/7321/143471/5705/5788/3115/5709/5695/4792/3113/5711/3117/5683/55824/5699/5702/26191/3127/7334/3551/5062/5696/5691/7314/5718/8945/3635/5290/5700/122706/5707/8767/23198/23118/10892/8517/5970/9861/5588/5698/5692/5713/1445/5710/916/5719/6233/3702/3932/3120/5170/3937/3123/5706/3122/920/8915/5714/5795/5688/5687/5708/7189/7535/5704/7311/5694/5058/997/1147/55740/9402/5684/5720/6885/4690/3119/84433/5690/5717/9491/6500/10197/919/7316/10213/50852/7322/5715/5701/27040/23291/915/5685/917/51466/5686/7408/5728/7454/5716/5296/5693/5721 110 Human_cytomegalovirus R-HSA-69202 Cyclin E associated events during G1/S transition 82/5218 83/10654 1.1810660835596782e-24 2.4455015377235692e-23 9.342488679551015e-24 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/91768/5934/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/7029/1163/1019/5706/286826/4331/5714/5688/5687/91750/5708/1874/208/5704/55957/7311/5694/1017/5684/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5715/5701/5685/5686/5716/1022/5693/5721/132660 82 Human_cytomegalovirus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 121/5218 134/10654 1.2075760434093625e-24 2.4641551726382352e-23 9.41375069690594e-24 5295/8454/5689/3725/4893/5335/4790/5682/5291/7321/143471/5705/5530/5709/5695/4792/5711/5683/2534/5699/5702/2885/9846/3845/7334/3265/3551/5062/5696/5691/7314/5879/257397/5718/8945/5601/4773/5290/5700/122706/5707/5336/5594/4214/23198/23118/10892/8517/5970/9861/5588/5698/5692/5713/5710/10454/5719/6233/7410/7409/3702/2353/3710/801/805/5170/6464/4772/3937/10451/5706/6850/8915/5714/5688/5687/4067/5708/5602/695/7189/6654/5704/7311/5694/5058/6416/997/5595/1147/9402/5684/5720/6885/84433/5690/5532/5717/9491/6500/3708/10197/7316/10213/10768/7322/5715/5701/27040/23291/5685/5686/5534/5609/5716/5296/808/5599/5693/5721/2207 121 Human_cytomegalovirus R-HSA-156842 Eukaryotic Translation Elongation 90/5218 93/10654 1.5440342991973344e-24 3.1057147046712097e-023 1.1864684614884781e-23 6158/6138/6227/6206/6234/6191/6128/6132/1917/6129/1915/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6166/1938/6136/6125/1937/6232/6160/1933/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/1936/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 90 Human_cytomegalovirus R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 100/5218 106/10654 2.0616825901857586e-24 4.0885198408190815e-23 1.5619270623942514e-23 374/85439/8674/4738/7039/1212/23208/950/554/10980/22848/7037/3482/408/10987/6456/185/30011/2885/163/11037/23149/9185/7314/9856/1839/161/7018/25977/10618/8027/1856/9892/8322/2060/2069/1601/6453/55707/8301/1129/9146/6455/4074/26119/29979/6233/90019/7474/6844/1213/1211/29924/4036/255324/1175/85021/6869/1173/6857/84251/29988/409/160/338/8218/920/22905/2873/7311/1956/8533/8673/50618/51138/9318/685/127833/1080/29978/58513/7316/1950/3267/3949/867/9341/915/917/6572/115548/1861/143425/3575/6845/551/154/10254/6457/50813 100 Human_cytomegalovirus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 79/5218 80/10654 9.923953633314573e-24 1.9406842660704056e-22 7.413947816701386e-23 8454/5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 79 Human_cytomegalovirus R-HSA-156902 Peptide chain elongation 86/5218 89/10654 2.4320224789696327e-23 4.690805000533209e-22 1.7920165634513083e-22 6158/6138/6227/6206/6234/6191/6128/6132/6129/1915/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6166/1938/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 86 Human_cytomegalovirus R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 113/5218 125/10654 3.422416267170471e-23 6.511840681318951e-22 2.4877022937754063e-22 56955/4240/3270/9210/10272/2153/7857/29106/91851/6696/51156/1435/265/11098/10130/2200/80341/375056/1114/720/10117/3956/3569/54972/2519/8720/7018/5340/10618/11167/813/5179/8074/4312/51246/348/4924/4313/3484/102/8614/336/6694/4148/174/57104/2335/7466/116519/2266/51280/7076/2243/84141/3488/2147/8542/4221/351/4052/7184/56975/334/3912/338/64856/335/5611/197/3053/3895/5624/1000/54757/3481/8404/255738/3913/354/652/57719/147111/2719/3487/3371/54587/3485/401138/3486/7425/6383/3827/3490/5589/2621/3915/5768/1471/1462/10232/462/3698/5265/1758/258/11320/5954/3479/213/10970/5034/1356/718 113 Human_cytomegalovirus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 85/5218 88/10654 4.8393190627947766e-23 9.085014987220061e-22 3.47072567170264e-22 8454/7531/11190/203068/54801/79441/5116/5048/8655/6790/9702/7846/7840/11064/5518/55835/23332/93323/7314/8945/4659/1454/983/79959/10540/6233/54930/54820/1453/9793/4218/5500/11258/22981/8636/7532/84962/55125/10382/121441/7277/9133/9814/23354/891/9738/1639/55722/4957/5566/7283/22919/22994/79866/1069/5577/7311/10133/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/6500/1781/7316/80321/10121/84131/23291/3320/10733/4751/80254/9662/55142/8481/55755 85 Human_cytomegalovirus R-HSA-5607764 CLEC7A (Dectin-1) signaling 95/5218 101/10654 5.704187915377153e-23 1.0567758664277674e-21 4.037174549525936e-22 8454/5689/4790/5682/7321/9039/29108/143471/5705/5530/5709/5695/4792/5711/5683/5699/5702/7334/3551/5696/5691/7314/257397/5718/8945/4773/5700/122706/5707/5336/23198/23118/10892/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/3710/801/4791/805/5170/4772/5706/64581/6850/8915/5714/5688/5687/5708/7189/5704/7311/5971/5694/997/1147/5684/5720/6885/84433/5690/3553/5532/5717/9491/6500/3708/10197/7316/10213/10768/7322/5715/5701/23291/5685/5686/5534/5716/808/5693/5721 95 Human_cytomegalovirus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 75/5218 76/10654 1.6892266466924774e-22 3.088871582523387e-21 1.1800339254406782e-21 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 75 Human_cytomegalovirus R-HSA-69052 Switching of origins to a post-replicative state 86/5218 90/10654 2.8455263119408467e-22 5.136539804118862e-21 1.9622995214598824e-21 8454/5689/9134/11065/5682/7321/8697/143471/5705/5709/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/29882/5001/5696/5691/7314/996/5718/5700/122706/5707/23198/898/890/51433/9861/6502/5698/5692/5713/119504/4175/5710/7324/5719/64682/6233/4172/5000/246184/4173/5706/8881/5714/5688/5687/5708/81620/10393/5704/51343/7311/25906/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 86 Human_cytomegalovirus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 74/5218 75/10654 3.4288737668868195e-22 6.111207928831192e-21 2.3346495601321318e-21 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 74 Human_cytomegalovirus R-HSA-8878166 Transcriptional regulation by RUNX2 109/5218 121/10654 4.126803483599692e-22 7.208692038866865e-21 2.753918684106585e-21 8454/8493/5689/7291/5682/5925/143471/5705/5709/9978/5695/9759/10413/4089/3549/5711/650/5683/2101/5699/5702/5696/5691/7314/5718/25/6662/5700/122706/5707/5594/3280/23198/10013/2737/865/11059/983/6714/2099/9861/2932/6502/5698/10000/5692/5713/595/5710/5719/6233/7525/10432/133522/4091/117581/1019/3958/5706/3678/1277/891/5714/6772/2736/5688/5687/4322/2908/5708/4488/208/5704/23493/7311/367/860/5694/5595/57154/5684/8841/5720/23462/10273/207/5690/5717/9491/6500/4086/59269/10197/7316/10213/4094/1026/5715/5701/5685/5686/55294/861/5716/25937/581/5693/5721/10891 109 Human_cytomegalovirus R-HSA-202424 Downstream TCR signaling 92/5218 98/10654 4.1470458462231256e-22 7.208692038866865e-21 2.753918684106585e-21 5295/8454/5689/4790/5682/5291/7321/143471/5705/3115/5709/5695/4792/3113/5711/3117/5683/5699/5702/3127/7334/3551/5696/5691/7314/5718/8945/3635/5290/5700/122706/5707/8767/23198/23118/10892/8517/5970/9861/5588/5698/5692/5713/5710/916/5719/6233/3932/3120/5170/3123/5706/3122/920/8915/5714/5688/5687/5708/7189/5704/7311/5694/997/1147/5684/5720/6885/3119/84433/5690/5717/9491/6500/10197/919/7316/10213/50852/7322/5715/5701/23291/915/5685/917/5686/5728/5716/5296/5693/5721 92 Human_cytomegalovirus R-HSA-192823 Viral mRNA Translation 85/5218 89/10654 5.599437146908007e-22 9.4988042202969565e-021 3.628804542891556e-21 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/5611/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 85 Human_cytomegalovirus R-HSA-3371556 Cellular response to heat stress 85/5218 89/10654 5.599437146908007e-22 9.4988042202969565e-021 3.628804542891556e-21 23165/6782/573/7531/1915/817/9530/348995/472/57122/3313/23511/3305/23279/1387/259217/23225/3309/9531/2475/3306/27000/9972/23411/8021/6117/3312/55746/51182/818/3303/6118/5594/3308/84335/10049/10013/3337/10762/9261/79902/9883/2932/6396/129401/3297/57521/4928/5903/55706/7175/1410/4927/64223/6119/26353/57805/3281/3310/7266/816/8086/3326/3304/10728/5595/815/81929/9631/116835/545/79023/23636/10808/53371/9532/9688/7415/3320/2033/6767/22824/9529/2288/8480 85 Human_cytomegalovirus R-HSA-9007101 Rab regulation of trafficking 111/5218 124/10654 5.904236527611084e-22 9.896625036757627e-21 3.780783039610607e-21 5869/163486/116442/126003/7531/22878/1122/54453/57533/10981/5861/163259/5866/23011/9610/60684/3257/414918/51762/51552/9230/83452/126432/201475/5874/79961/2665/79090/22898/58485/4943/5868/81846/51622/7249/23637/84079/51209/5872/9827/80006/5870/8408/9909/10000/64786/51112/117177/83696/1121/23682/27095/6399/7109/4218/7879/2664/201627/26088/27342/23258/9363/5864/10260/382/57679/81876/9135/259173/6305/51693/8567/208/5867/79890/22879/10133/11345/54734/57589/84315/7248/22931/51399/10890/23062/207/11337/51256/122553/79958/57706/8766/22930/55667/26130/27147/25782/9367/51560/11021/5873/79735/81631/5878/11031/23163/338382/57465/89781/160518 111 Human_cytomegalovirus R-HSA-72764 Eukaryotic Translation Termination 88/5218 93/10654 7.0946355194157e-22 1.1752055072161536e-20 4.4896083596550125e-21 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/51504/6147/6222/2935/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/2107/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/23708/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 88 Human_cytomegalovirus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72/5218 73/10654 1.4116294308725435e-21 2.3111328356610945e-20 8.829163270206485e-21 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/5716/701/5693/5721 72 Human_cytomegalovirus R-HSA-2500257 Resolution of Sister Chromatid Cohesion 112/5218 126/10654 1.4936485058316881e-21 2.4173070071391e-20 9.234777815849882e-21 55839/11130/6249/9735/5526/51807/9212/347688/10274/147841/348995/10381/57122/1780/23122/5048/57405/8655/23279/2491/7846/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/55869/3619/64105/332/5528/983/79902/3796/5519/81565/91687/10376/83540/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/55055/80776/1783/401541/10382/79172/7277/9133/79980/6232/23047/5885/891/5501/54821/9183/1062/699/22919/8243/5529/51143/10383/5347/84790/84643/7280/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23244/23421/55920/79023/10735/1781/4085/55166/79003/9126/5527/701/57551 112 Human_cytomegalovirus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 71/5218 72/10654 2.8630058593660215e-21 4.4790136110970644e-20 1.711106425890102e-20 5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 71 Human_cytomegalovirus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 71/5218 72/10654 2.8630058593660215e-21 4.4790136110970644e-20 1.711106425890102e-20 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 71 Human_cytomegalovirus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 71/5218 72/10654 2.8630058593660215e-21 4.4790136110970644e-20 1.711106425890102e-20 5689/9134/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/990/5699/5702/8900/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/898/890/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/1017/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 71 Human_cytomegalovirus R-HSA-141424 Amplification of signal from the kinetochores 89/5218 96/10654 2.1357688506782067e-20 3.268654936690125e-19 1.2487161129251303e-19 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/79902/3796/5519/81565/91687/83540/7514/54820/6396/64946/9793/140735/220134/4928/5903/55055/80776/1783/401541/79172/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/55166/79003/5527/701/57551 89 Human_cytomegalovirus R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 89/5218 96/10654 2.1357688506782067e-20 3.268654936690125e-19 1.2487161129251303e-19 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/79902/3796/5519/81565/91687/83540/7514/54820/6396/64946/9793/140735/220134/4928/5903/55055/80776/1783/401541/79172/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/55166/79003/5527/701/57551 89 Human_cytomegalovirus R-HSA-909733 Interferon alpha/beta signaling 68/5218 69/10654 2.3843395828267692e-20 3.609838852279668e-19 1.3790577553191616e-19 3443/5777/3442/5770/3107/9021/11274/3662/3106/4599/684/3133/3429/91543/4938/5696/3445/10410/9636/2634/3444/103/3434/3433/3451/3448/3661/3439/10581/3452/4940/3437/6773/7297/5781/3430/3660/3446/3135/3665/10379/3455/4600/8638/3394/3663/6772/8651/3659/25939/3440/3454/3716/3456/3105/3441/51447/54739/2537/3449/8519/3664/6041/1958/4939/6059/3669/3134 68 Human_cytomegalovirus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 79/5218 83/10654 3.2083640874049675e-20 4.8057198245385045e-19 1.8359171877535706e-19 8454/5689/4893/4790/5579/5682/143471/5705/5530/5709/5695/4792/5711/5683/5699/5702/4794/3845/3265/3551/5696/5691/7314/5718/8945/4773/5966/5700/122706/5707/23198/10892/8517/5970/9861/5698/5692/5713/5710/2280/5478/5719/6233/801/805/4772/5706/8915/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/84433/5690/5532/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5534/5716/808/5693/5721 79 Human_cytomegalovirus R-HSA-9020702 Interleukin-1 signaling 94/5218 103/10654 3.2723630510674045e-20 4.849986500950426e-19 1.852828276006032e-19 8454/5689/4790/5682/8878/143471/5705/5709/9978/5695/4792/5711/5683/5699/5702/3654/51135/7334/3551/5696/5691/7314/257397/5718/8945/1326/11213/5700/122706/5707/8767/23198/23118/8517/5970/9861/5698/5692/5713/5710/10454/5719/6233/7850/5608/4791/3557/351/54472/5706/79155/5714/3552/5688/5687/5708/3656/57162/7189/5704/7311/5694/6416/3554/3556/1147/5684/5720/6885/5604/4215/10392/5690/3553/5717/9491/6500/10197/4615/7316/10213/4793/3146/5715/5701/23291/5685/5686/6288/6285/5716/57161/5693/5721 94 Human_cytomegalovirus R-HSA-8854518 AURKA Activation by TPX2 71/5218 73/10654 5.43868690708842e-20 7.976740797063015e-19 3.0473344402655514e-19 7531/11190/203068/54801/79441/5116/5048/8655/6790/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/22974/3161/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 71 Human_cytomegalovirus R-HSA-1169091 Activation of NF-kappaB in B cells 66/5218 67/10654 9.781582530989782e-20 1.4053538983299606e-18 5.368838532047023e-19 8454/5689/4790/5579/5682/143471/5705/5709/5695/4792/5711/5683/5699/5702/4794/3551/5696/5691/7314/5718/8945/5966/5700/122706/5707/23198/10892/8517/5970/9861/5698/5692/5713/5710/5719/6233/5706/8915/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/84433/5690/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5716/5693/5721 66 Human_cytomegalovirus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 66/5218 67/10654 9.781582530989782e-20 1.4053538983299606e-18 5.368838532047023e-19 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 66 Human_cytomegalovirus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 100/5218 112/10654 1.053972897134955e-19 1.4989836759252693e-18 5.726530041849676e-19 5295/8454/5689/5777/4893/4790/5579/5682/143471/5705/5530/5709/5695/4792/5711/5683/2534/5699/5702/30011/2885/4794/3845/3265/3551/973/5696/5691/7314/5718/8945/4773/5966/5700/122706/5707/5336/23198/10892/8517/5970/9861/5698/5692/5713/5710/2280/5478/5719/6233/7409/3710/801/805/4772/930/5706/6850/8915/5714/5688/5687/4067/29760/5708/695/6654/5704/7311/5293/5694/1147/5684/5720/6885/4690/640/84433/5690/5532/5717/9491/6500/3708/10197/7316/10213/10768/4793/5715/5701/23291/5685/5686/5534/974/5716/808/5693/5721 100 Human_cytomegalovirus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 97/5218 108/10654 1.3881464213545244e-19 1.9545101612671704e-18 7.4667665401280215e-19 5295/3605/7124/2308/1052/7291/356/3593/246/9021/3082/5743/3091/3383/6097/6657/3576/3662/3688/4985/7133/3606/4609/4988/3717/2162/6347/7040/3312/3569/4692/3596/3598/3592/7412/4582/4312/6778/332/4313/3565/3934/3976/5443/3718/598/2247/2335/595/7157/2353/604/7076/51561/3570/7297/9655/3566/7184/3684/4318/3726/58480/301/6774/6772/8651/1901/3552/79923/3716/240/6356/5008/3586/596/2309/3561/207/5292/5451/7422/3553/2625/4314/1026/3320/4843/6288/948/6935/3687/7431/3162/1278/4170/3689 97 Human_cytomegalovirus R-HSA-8878159 Transcriptional regulation by RUNX3 88/5218 96/10654 2.545549258369683e-19 3.54864688691536e-18 1.3556807410389871e-18 5689/5682/182/5705/6097/6696/5709/5695/9759/10413/4609/4089/22938/5711/1387/7005/4088/5683/5699/5702/9794/7040/3845/5696/5691/7314/5718/8463/2648/5700/5707/55534/3280/84441/463/3683/865/6714/9861/8850/5698/5692/5713/595/5710/7157/5719/6233/1029/864/5706/10046/5714/6934/5688/5687/5708/5704/7311/5694/4851/3676/57154/5684/5720/2309/1499/10018/5690/5717/9491/10197/64750/7316/10213/1026/5715/5701/5685/5686/2033/861/5716/25937/3516/5693/5721/4193 88 Human_cytomegalovirus R-HSA-72202 Transport of Mature Transcript to Cytoplasm 79/5218 84/10654 2.8040462684504644e-19 3.8632667250513854e-018 1.4758741750158927e-18 23165/8683/6431/84271/199746/348995/57122/23511/81608/65109/23279/23225/9877/9972/8021/55746/7919/53981/6432/8563/6430/56001/80145/10762/22794/9785/11338/29107/4116/79902/9883/51213/10250/26097/51362/1977/57187/6396/129401/79228/2733/84324/4928/5903/55706/7175/6428/10212/55110/84321/6429/4927/10898/10569/9295/10482/51692/8086/9939/6426/22916/10921/81929/9631/29894/79023/23636/4686/8189/53371/7307/9688/9984/10189/9775/84248/6427/8480/55339 79 Human_cytomegalovirus R-HSA-877300 Interferon gamma signaling 85/5218 92/10654 2.826111311649806e-19 3.8632667250513854e-018 1.4758741750158927e-18 80263/5777/960/5770/3107/817/9021/3383/55223/3662/3115/4684/567/6672/3113/3106/3717/3117/11074/5371/3133/117854/3127/4938/4261/818/115362/7412/85363/9830/163351/2634/115361/10475/10437/10612/3458/3661/5580/81603/10107/4940/5781/3660/8554/3135/3665/3120/10379/2633/3123/23650/2209/8638/7706/23087/3122/3394/3663/6772/8651/3659/2635/5771/816/10346/3716/7726/79097/3105/815/6737/23321/4281/3119/4502/51127/3664/4939/388646/7341/55128/3134/80128/5724 85 Human_cytomegalovirus R-HSA-5663220 RHO GTPases Activate Formins 119/5218 140/10654 3.2857995971698015e-19 4.420552808290346e-18 1.6887727908465662e-18 55839/11130/71/6249/9735/5526/51807/9212/347688/388/147841/348995/10381/57122/1780/23122/3688/5048/57405/8655/23279/2491/7846/1060/11004/1855/9184/5518/23332/25909/10726/81930/55746/5879/5515/79682/10403/25936/1856/389/3619/64105/332/5528/6714/79902/3796/5519/81565/91687/10376/83540/1857/7514/54820/29984/1729/6396/64946/9793/140735/220134/84617/4928/114793/5903/55055/80776/1783/401541/10382/79172/7277/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/998/10383/5347/387/60/84790/84643/7280/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/5216/81624/55166/51466/79003/5527/701/23380/57551 119 Human_cytomegalovirus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 93/5218 103/10654 3.2965770232278853e-19 4.420552808290346e-18 1.6887727908465662e-18 5295/374/3643/2250/5291/5526/7039/3082/941/2064/145957/2534/9965/2264/3630/3654/9542/2885/51135/8660/5518/2252/2253/5879/5515/1839/5290/3667/8823/90865/2065/3815/5594/2069/8074/2260/5528/2249/6714/2099/2248/5519/2247/5880/7409/2246/2251/5154/3932/8394/255324/5781/940/930/2263/4233/8503/5159/3084/5529/7189/9365/10718/5293/1956/2549/5595/3556/5516/8822/685/5305/5525/207/8817/4615/2100/2254/1950/50852/26281/10818/2261/2255/391/2066/27006/942/5527/5155/4254/5296/5156 93 Human_cytomegalovirus R-HSA-199418 Negative regulation of the PI3K/AKT network 98/5218 110/10654 3.5689377509231625e-19 4.74062674839605e-18 1.8110498418289335e-18 5295/374/3643/2250/23035/5291/5526/7039/3082/941/2064/145957/2534/9965/2264/3630/3654/9542/2885/51135/8660/5518/2252/2253/5879/5515/1839/5290/3667/8823/90865/2065/3815/5594/2069/8074/2260/5528/2249/6714/2099/2248/5519/2247/5880/10000/7409/2246/2251/5154/3932/8394/255324/5781/940/23239/930/2263/4233/8503/5159/3084/5529/7189/208/9365/10718/5293/1956/2549/5595/3556/5516/8822/685/5305/5525/207/8817/4615/2100/2254/1950/50852/26281/10818/2261/2255/391/5728/2066/27006/942/5527/5155/4254/5296/5156 98 Human_cytomegalovirus R-HSA-8873719 RAB geranylgeranylation 64/5218 65/10654 4.007751400352782e-19 5.273751375417492e-18 2.0147181166554567e-18 5869/116442/1122/10981/5861/23011/51762/376267/51552/9230/83452/27314/10966/201475/5874/339122/5868/55647/51209/326624/5872/9545/57111/347517/5870/1121/23682/4218/401258/142684/7879/5875/51715/25837/115827/401409/9363/5864/57799/53917/57403/81876/8934/5867/54734/115273/83871/53916/22931/9609/64284/10890/84932/5862/8766/9367/5876/51560/11021/5873/5878/11031/5865/338382 64 Human_cytomegalovirus R-HSA-380259 Loss of Nlp from mitotic centrosomes 68/5218 70/10654 4.344569699730498e-19 5.612068015798662e-18 2.1439643810355237e-18 7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 68 Human_cytomegalovirus R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 68/5218 70/10654 4.344569699730498e-19 5.612068015798662e-18 2.1439643810355237e-18 7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 68 Human_cytomegalovirus R-HSA-1236974 ER-Phagosome pathway 78/5218 83/10654 5.4278425229417545e-19 6.947638429365446e-18 2.654189023180131e-18 8773/5689/5682/3107/811/143471/5705/10333/5709/5695/567/3106/5711/5683/929/5699/5702/3133/3551/5696/5691/7314/5718/10952/5700/122706/5707/23198/6892/8517/6810/7096/9861/5698/5692/5713/5710/5719/6233/3135/6890/5706/29927/5714/5688/5687/5708/2923/695/5704/7311/5694/8673/3105/23643/1147/5684/5720/5690/5717/9491/10197/7099/4615/6891/7316/10213/5715/5701/9341/5685/5686/948/5716/3134/7097/5693/5721 78 Human_cytomegalovirus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 62/5218 63/10654 1.6399098918335691e-18 2.080173988920419e-17 7.946836934347595e-18 5689/11065/5682/7321/8697/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/5707/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 62 Human_cytomegalovirus R-HSA-2408557 Selenocysteine synthesis 85/5218 93/10654 1.7087732161267373e-18 2.1481720431307553e-17 8.206608209029725e-18 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/51091/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 85 Human_cytomegalovirus R-HSA-69615 G1/S DNA Damage Checkpoints 66/5218 68/10654 1.731805789623752e-18 2.1578606653010996e-17 8.243621411250465e-18 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/993/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/1111/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 66 Human_cytomegalovirus R-HSA-69002 DNA Replication Pre-Initiation 79/5218 85/10654 2.0666712159954074e-18 2.5525202387030995e-17 9.751329560236873e-18 5689/5682/143471/5705/5709/5422/1869/4174/5695/84515/4998/5711/10926/5683/990/5699/5702/55388/6117/5001/5696/5691/7314/5718/6118/5700/122706/5707/23198/5557/9861/5698/5692/5713/4175/5710/5719/6233/23649/4172/5000/8318/54107/4173/5706/5714/51053/6119/5688/5687/5427/5708/81620/1870/5704/7311/5694/4176/56655/1017/5684/5720/8317/5690/5717/9491/10197/7316/10213/5426/4171/1871/5715/5701/5685/5686/5716/5693/5721 79 Human_cytomegalovirus R-HSA-162587 HIV Life Cycle 126/5218 152/10654 2.253733523544853e-18 2.7593537401314376e-17 1.0541490439646865e-17 6884/23165/6875/51652/2237/7852/27243/6874/348995/57122/3981/5431/23511/5435/5433/2960/51271/23279/23327/29082/8732/23225/2965/27183/5439/6873/3836/9972/6881/51616/8021/11198/904/51497/55746/92421/7314/137492/25978/51160/2959/10015/91782/5438/10762/79720/4836/9397/79902/9883/83860/51510/2068/5902/5478/6233/7514/1025/6396/129401/6883/7936/6829/2957/4928/2963/5434/5903/55706/7175/5436/6878/920/4331/4927/8148/2962/54457/8812/128866/2071/5901/8086/7311/93343/6880/6908/7251/1104/2547/6882/2961/5432/22916/1234/6877/5905/6917/81929/5440/902/9631/3159/5430/5045/7520/6749/79023/5441/23636/4686/7316/6872/53371/9688/9150/6879/9525/2958/5437/8815/2968/138474/1022/8178/8480 126 Human_cytomegalovirus R-HSA-168898 Toll-like Receptor Cascades 128/5218 155/10654 2.2831993596852848e-18 2.771331636583518e-17 1.05872492994481e-17 8454/3725/10695/9252/4790/7321/1848/1785/6280/10333/4792/1432/2244/929/3654/51135/6196/1759/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/54106/11035/8945/1326/5601/5606/11213/8737/8767/5336/1849/29110/5594/6271/4214/23118/841/8517/5528/7323/5970/7096/9261/5519/5598/4208/6195/10454/3661/6233/51311/10010/2266/2353/2243/8772/5600/5781/30849/5608/4791/1508/1514/3665/351/81793/7184/3684/8411/330/7098/338/79155/6279/8651/26052/7867/5602/3656/57162/695/7189/81622/7311/9641/6416/51284/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7100/7316/4205/5289/4793/5641/3146/7322/329/23291/6288/6285/5609/948/1520/1385/5599/353376/7097/57161/3689/148022 128 Human_cytomegalovirus R-HSA-432722 Golgi Associated Vesicle Biogenesis 56/5218 56/10654 3.7477563453329726e-18 4.5101204566058334e-17 1.7229900966847944e-17 27131/162/1176/5286/1174/1785/8546/7037/3482/408/6456/7164/3312/1362/26258/25977/10618/6643/10053/55330/8301/2495/388552/152503/6844/54885/1213/2580/1211/23431/8907/84062/9685/9026/8775/9829/8905/51429/64746/8673/23557/2512/164/130340/6272/2804/2647/7163/286451/9698/5878/81567/10717/6845/375/4952 56 Human_cytomegalovirus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 75/5218 80/10654 3.9167547288763934e-18 4.6735514053033573e-17 1.7854252153932537e-17 3839/23165/5335/348995/317649/57122/11274/23511/4734/23279/8672/23225/1973/3836/4599/9972/8021/7334/4938/55746/7314/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/1977/51191/6233/5610/4940/6396/129401/4928/3838/5903/55706/7175/2316/4600/8638/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/7318/1974/5595/3837/81929/9631/79023/23636/7316/53371/9688/6041/4939/6059/5300/9775/5495/8480 75 Human_cytomegalovirus R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 98/5218 112/10654 6.590502321085995e-18 7.797838040410992e-17 2.978988665258685e-17 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6728/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/10952/6147/6222/6727/6184/58477/6134/6747/6731/6155/6729/6231/6142/23521/6185/6207/6233/6188/200916/6122/6230/6194/6166/1650/6136/6125/6232/6160/6748/29927/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/6730/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/9789/6135/6201/6161/6133 98 Human_cytomegalovirus R-HSA-5678895 Defective CFTR causes cystic fibrosis 60/5218 61/10654 6.701028594525824e-18 7.822015457007703e-17 2.988225103566789e-17 5689/5682/143471/91319/5705/5709/5695/5711/5683/5699/6400/5702/51009/5696/5691/7314/5718/5700/122706/5707/10956/79139/91445/23198/9861/5698/5692/5713/5710/5719/10613/6233/27248/6048/5706/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 60 Human_cytomegalovirus R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 71/5218 75/10654 6.815126292717261e-18 7.822015457007703e-17 2.988225103566789e-17 23165/8683/6431/84271/199746/348995/57122/23511/65109/23279/23225/9877/9972/8021/55746/7919/6432/8563/6430/56001/80145/10762/22794/9785/11338/29107/4116/79902/9883/51213/10250/26097/51362/57187/6396/129401/79228/2733/84324/4928/5903/55706/7175/6428/10212/55110/84321/6429/4927/10569/9295/10482/8086/9939/6426/22916/10921/81929/9631/79023/23636/4686/53371/7307/9688/9984/10189/9775/84248/6427/8480 71 Human_cytomegalovirus R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 71/5218 75/10654 6.815126292717261e-18 7.822015457007703e-17 2.988225103566789e-17 5295/374/2250/5291/7039/3082/941/2064/145957/2534/9965/2264/9542/2885/8660/2252/2253/5879/1839/5290/3667/8823/2065/3815/2069/8074/2260/2249/6714/2099/2248/2247/5880/7409/2246/2251/5154/3932/255324/5781/940/930/2263/4233/8503/5159/3084/9365/10718/5293/1956/2549/8822/685/8817/2100/2254/1950/50852/26281/10818/2261/2255/391/2066/27006/942/5155/4254/5296/5156 71 Human_cytomegalovirus R-HSA-69563 p53-Dependent G1 DNA Damage Response 64/5218 66/10654 6.888706794523829e-18 7.822015457007703e-17 2.988225103566789e-17 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Human_cytomegalovirus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 64/5218 66/10654 6.888706794523829e-18 7.822015457007703e-17 2.988225103566789e-17 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Human_cytomegalovirus R-HSA-3858494 Beta-catenin independent WNT signaling 121/5218 146/10654 1.1137846633867698e-17 1.2545670448388573e-16 4.7927912672895954e-17 2788/5689/5579/5682/5578/1212/5582/27327/143471/5705/2775/5530/5709/5695/5881/5711/5683/5699/2782/5702/192669/1855/163/4343/3845/5696/5691/4920/7314/5879/2787/5718/161/51701/5700/122706/5707/1856/8322/23198/10681/7471/2792/9861/5698/5880/5692/5713/2785/2783/2784/5710/5719/6233/7474/1857/1213/3710/1211/7855/1175/26523/801/2791/805/1173/144165/4772/409/5706/160/5714/6934/5688/5687/5148/4919/5708/2786/5704/7311/387/5694/57154/27161/815/5684/5720/54331/6885/1499/59345/5690/5532/57690/5717/9491/50855/51764/94235/3708/10197/192670/64750/7316/10213/55970/5216/5715/5701/2793/5685/5686/5534/23112/5716/808/5693/5721/6259/2790 121 Human_cytomegalovirus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 59/5218 60/10654 1.3538467001169996e-17 1.4663201182805657e-16 5.601746265261432e-17 8454/5689/9134/5682/5705/5709/5753/5695/5711/5683/5699/5702/8900/5696/5691/7314/5718/5700/5707/898/890/9861/6502/5698/5692/5713/595/5710/5719/6233/1163/1019/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/5690/5717/1027/9491/6500/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721 59 Human_cytomegalovirus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 59/5218 60/10654 1.3538467001169996e-17 1.4663201182805657e-16 5.601746265261432e-17 8454/5689/5682/9039/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/5970/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 59 Human_cytomegalovirus R-HSA-5610780 Degradation of GLI1 by the proteasome 59/5218 60/10654 1.3538467001169996e-17 1.4663201182805657e-16 5.601746265261432e-17 8454/5689/5682/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/83737/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/8650/9861/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/2735/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Human_cytomegalovirus R-HSA-5610783 Degradation of GLI2 by the proteasome 59/5218 60/10654 1.3538467001169996e-17 1.4663201182805657e-16 5.601746265261432e-17 8454/5689/5682/1452/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/9861/2932/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/2736/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Human_cytomegalovirus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 59/5218 60/10654 1.3538467001169996e-17 1.4663201182805657e-16 5.601746265261432e-17 8454/5689/5682/1452/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/2737/9861/2932/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Human_cytomegalovirus R-HSA-195253 Degradation of beta-catenin by the destruction complex 76/5218 82/10654 1.4427436864934366e-17 1.5389265989263323e-16 5.879122996795424e-17 8454/5689/5682/5526/1452/143471/5705/5709/9978/5695/5711/5683/324/5699/8312/5702/5518/5696/5691/7314/5515/5718/8945/5700/122706/5707/23198/5528/7091/9861/5519/2932/5698/5692/5713/5710/5719/6233/7089/7090/5706/23401/5714/6934/5688/5687/5708/5529/7088/5704/7311/5694/5516/5684/5720/1487/1499/5525/139285/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/3065/5527/1488/5716/5693/5721 76 Human_cytomegalovirus R-HSA-9013694 Signaling by NOTCH4 76/5218 82/10654 1.4427436864934366e-17 1.5389265989263323e-16 5.879122996795424e-17 8454/5689/5682/182/23385/5705/5709/9978/5695/22938/5711/1387/4088/5683/5699/4853/5702/9794/388585/5696/5691/7314/5718/2648/5700/5707/55534/3280/84441/7534/102/9861/8850/5698/5692/5713/5710/5719/6233/2324/5663/5706/10460/10046/5714/5688/5687/5708/59/4855/5704/23493/7311/5694/4851/5684/5720/23462/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/2033/55294/5716/3516/5693/5721 76 Human_cytomegalovirus R-HSA-162599 Late Phase of HIV Life Cycle 116/5218 139/10654 1.8134879568906717e-17 1.9198428897008012e-16 7.334328025098008e-17 6884/23165/6875/51652/27243/6874/348995/57122/5431/23511/5435/5433/2960/51271/23279/23327/29082/8732/23225/2965/27183/5439/6873/9972/6881/51616/8021/11198/904/51497/55746/92421/7314/137492/25978/51160/2959/10015/91782/5438/10762/79720/4836/9397/79902/9883/83860/51510/2068/5902/5478/6233/7514/1025/6396/129401/6883/7936/6829/2957/4928/2963/5434/5903/55706/7175/5436/6878/4331/4927/8148/2962/54457/8812/128866/2071/5901/8086/7311/93343/6880/6908/7251/1104/6882/2961/5432/22916/6877/5905/6917/81929/5440/902/9631/5430/5045/6749/79023/5441/23636/4686/7316/6872/53371/9688/9150/6879/9525/2958/5437/2968/138474/1022/8178/8480 116 Human_cytomegalovirus R-HSA-8948751 Regulation of PTEN stability and activity 66/5218 69/10654 2.0743673655784268e-17 2.1796337692047949e-16 8.326800658370591e-17 5689/5682/1459/1460/143471/5705/5709/5695/1457/4734/11060/5711/5683/5699/2444/5702/8975/80351/5696/5691/7314/5718/5700/122706/5707/23198/9861/81847/5698/10000/5692/5713/5710/5719/6233/331/23608/5706/8658/5714/5688/5687/5708/208/5704/7311/5694/5684/5720/10273/207/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5728/5987/5716/5693/5721 66 Human_cytomegalovirus R-HSA-8939902 Regulation of RUNX2 expression and activity 69/5218 73/10654 2.5814679527287955e-17 2.692375464771959e-16 1.0285615000736176e-16 8454/5689/7291/5682/143471/5705/5709/9978/5695/5711/650/5683/2101/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/865/11059/2099/9861/2932/6502/5698/5692/5713/5710/5719/6233/133522/5706/5714/6772/5688/5687/2908/5708/4488/5704/7311/860/5694/57154/5684/5720/10273/5690/5717/9491/6500/59269/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721/10891 69 Human_cytomegalovirus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 58/5218 59/10654 2.734245125930756e-17 2.8307478950812536e-16 1.0814235753487743e-16 8454/5689/5682/9039/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 58 Human_cytomegalovirus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 144/5218 182/10654 3.0700699717694984e-17 3.155225197263835e-16 1.205382831789638e-16 1912/23165/7068/7486/9112/6045/9212/80012/10274/348995/6613/57122/23511/28996/54780/4792/3190/9759/9612/8856/1911/9994/6790/6672/23279/1387/23225/23512/57332/7022/7067/7428/1107/5371/8924/672/115426/9972/10499/6612/5914/8021/6117/11315/55746/7421/4286/10062/7150/6670/83746/3622/1788/51564/51588/3619/7153/51602/2516/8517/332/10762/1655/5970/2099/79902/2494/9656/9883/84733/3066/7157/668/7158/10155/9063/7155/6396/129401/7703/4791/6015/8554/7020/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/5111/4927/10521/1616/2908/8243/142/9971/1069/8086/7329/367/25942/9641/648/23468/5905/81929/5893/1487/55143/9631/5468/7021/8204/3090/79023/23636/10735/3183/4306/53371/6996/9688/7341/10401/2033/9126/3065/6256/5987/6294/8648/6304/8480/10891/7508/4193 144 Human_cytomegalovirus R-HSA-1236975 Antigen processing-Cross presentation 88/5218 99/10654 3.4040846074588195e-17 3.473152990798563e-16 1.3268399957371905e-16 8773/5689/5682/3107/811/143471/5705/10333/5709/5695/567/3693/3106/5711/5683/929/5699/5702/3133/3551/5696/5691/7314/5718/10952/5700/122706/5707/23198/6892/8517/6810/7096/9861/5698/5692/5713/5710/5719/6233/3685/1535/1514/3135/4688/6890/2209/5706/29927/5714/5688/5687/5708/2923/695/9902/5704/4012/7311/5694/8673/3105/23643/1147/5684/5720/5690/5717/9491/10197/7099/4615/6891/7316/10213/5715/5701/9341/5685/5686/948/1520/5716/3134/7097/1536/5693/5721 88 Human_cytomegalovirus R-HSA-1169408 ISG15 antiviral mechanism 68/5218 72/10654 5.01773417840205e-17 5.082712031072004e-16 1.9417358312483513e-16 3839/23165/5335/348995/317649/57122/11274/23511/4734/23279/8672/23225/1973/3836/4599/9972/8021/7334/55746/7314/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/1977/51191/6233/5610/6396/129401/4928/3838/5903/55706/7175/4600/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/7318/1974/5595/3837/81929/9631/79023/23636/7316/53371/9688/5300/9775/5495/8480 68 Human_cytomegalovirus R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 112/5218 134/10654 5.1917899778402615e-17 5.221457349142205e-16 1.9947403599070483e-16 5579/2153/7042/5175/5578/5582/3082/29106/5267/7423/3920/374354/2244/7114/3309/3690/2162/87/7040/5874/54863/350/7043/5054/5099/1072/7018/6678/5340/813/7094/7414/10490/83706/7044/6810/7123/6694/3671/7273/22927/1191/3273/27154/226/2335/1/5478/94121/22915/2266/5154/7076/2243/801/805/351/135228/51097/7424/2316/3674/5552/2157/7277/334/10447/335/308/78991/6403/197/81/9948/3481/5473/8407/7450/29789/10916/139322/5005/7422/5004/5196/3827/1950/2621/5216/5768/710/6647/1893/5265/7078/55664/5345/54676/2/948/88/1675/3479/5155/51368/808/213/5660/7057/5627/6814/3700 112 Human_cytomegalovirus R-HSA-72187 mRNA 3'-end processing 57/5218 58/10654 5.520029764457559e-17 5.512199935004428e-16 2.1058120266053097e-16 8683/6431/84271/51585/199746/81608/1477/65109/9877/7919/53981/6432/8563/6430/11051/80145/8106/22794/9785/11338/4116/1478/51213/10250/26097/51362/23283/10914/57187/79228/84324/6428/10212/55110/84321/6429/10898/10569/9295/51692/9939/6426/22916/1479/10921/79869/29894/4686/8189/10978/7307/9984/10189/9775/84248/6427/55339 57 Human_cytomegalovirus R-HSA-5621481 C-type lectin receptors (CLRs) 117/5218 142/10654 9.477056125915973e-17 9.396968327668796e-16 3.5899004302024187e-16 8454/5689/4586/9252/4893/4790/5682/7321/9039/29108/143471/5705/5530/5709/5695/4792/5711/1387/5683/2534/5699/5702/5894/3845/7334/3265/3551/5062/5696/5691/7314/257397/5718/8945/4773/5700/122706/5707/5567/5336/4582/23198/23118/10892/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/3710/801/4791/805/5170/4772/338339/5568/5706/64581/6850/8915/5714/5566/170482/5688/5687/4067/5708/7189/5704/30835/7311/5971/4585/5694/5058/997/1147/5684/5720/6885/84433/5690/3553/5532/5717/9491/6500/3708/10197/7316/10213/94025/10768/7322/5715/5701/23291/5685/5686/2033/5534/5716/808/5693/5721/2207 117 Human_cytomegalovirus R-HSA-68949 Orc1 removal from chromatin 67/5218 71/10654 9.744644556119987e-17 9.594726947564296e-16 3.66544966373008e-16 8454/5689/5682/143471/5705/5709/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/5001/5696/5691/7314/5718/5700/122706/5707/23198/890/9861/6502/5698/5692/5713/4175/5710/5719/6233/4172/5000/4173/5706/5714/5688/5687/5708/81620/5704/7311/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 67 Human_cytomegalovirus R-HSA-2990846 SUMOylation 147/5218 188/10654 9.974494474454625e-17 9.752839041688968e-16 3.7258528336595867e-016 1912/10054/23165/7068/7486/9112/6045/9212/80012/10274/348995/6613/57122/23511/28996/54780/4792/3190/9759/9612/8856/1911/9994/6790/6672/23279/1387/23225/23512/57332/7022/7067/7428/1107/5371/8924/672/115426/9972/10499/6612/5914/8021/6117/11315/55746/7421/4286/10062/7150/6670/83746/3622/1788/51564/51588/3619/7153/51602/2516/8517/332/10762/1655/5970/2099/79902/2494/9656/9883/84733/3066/7157/668/7158/10155/9063/7155/6396/129401/7703/4791/6015/8554/7020/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/5111/4927/10521/1616/2908/8243/142/9971/1069/8086/7329/367/25942/9641/648/23468/5905/81929/5893/29843/1487/55143/9631/5468/7021/8204/3090/79023/23636/10735/3183/4306/53371/6996/9688/7341/10401/59343/2033/9126/3065/6256/5987/6294/8648/6304/8480/10891/7508/4193 147 Human_cytomegalovirus R-HSA-1234174 Cellular response to hypoxia 70/5218 75/10654 1.0362980120336965e-16 1.0062811040989274e-15 3.8442706653300834e-16 5689/5682/64344/7321/3091/143471/5705/5709/9978/5695/5711/1387/5683/5699/126374/7428/5702/2056/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/405/768/112399/84962/5706/5714/10370/5688/5687/5708/5704/7311/2034/55662/5694/5684/5720/7422/5690/5717/9491/10197/7316/10213/8994/7322/5715/5701/5685/5686/2033/8453/5716/54583/5693/5721 70 Human_cytomegalovirus R-HSA-4641258 Degradation of DVL 56/5218 57/10654 1.113979729542108e-16 1.0743037391748547e-15 4.1041358456814504e-16 5689/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/1855/5696/5691/7314/5718/5700/122706/5707/1856/23198/59349/9861/5698/5692/5713/5710/5719/6233/1857/5706/5714/5688/5687/5708/51339/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/23072/5693/5721 56 Human_cytomegalovirus R-HSA-5687128 MAPK6/MAPK4 signaling 80/5218 89/10654 2.054990690582578e-16 1.9683176138369185e-15 7.519514807645524e-16 2308/5689/3725/5682/27327/143471/5705/5709/5695/4609/5711/5683/5699/5702/192669/4343/5062/5696/5691/7314/5879/5718/5700/122706/5707/5567/23198/3337/983/9861/5698/5692/5713/5710/8555/896/5719/6233/7514/26523/10602/5568/3315/5706/5597/5714/5566/5688/5687/5708/998/5704/7311/5694/5058/27161/5684/5720/2309/10642/5690/57690/5717/9491/10197/192670/5596/8550/7316/10213/5715/5701/5685/5686/8556/23112/5716/8202/5693/5721 80 Human_cytomegalovirus R-HSA-8943724 Regulation of PTEN gene transcription 59/5218 61/10654 2.1524289999717262e-16 2.0477162378109397e-15 7.822839395345322e-16 1912/3725/6591/1822/9112/6045/80012/1911/5928/10325/23512/57332/1107/2475/1386/10670/64121/23186/2146/51564/5594/84232/7101/84733/57459/3066/7157/8726/57521/6015/28956/389541/9219/8535/5931/58528/1108/2122/64223/10014/54815/6009/55004/57504/648/23466/53615/5595/8841/5468/5978/153129/57167/1958/8649/6615/3065/23028/10542 59 Human_cytomegalovirus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 55/5218 56/10654 2.2471947736429115e-16 2.1093668275261464e-15 8.058361609344055e-16 5689/5682/26986/143471/5705/5709/5695/5711/5683/5699/5702/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/9861/5698/5692/5713/1981/5710/5719/6233/3315/5706/5714/5688/5687/5708/5704/7311/5694/3304/5684/5720/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 55 Human_cytomegalovirus R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 55/5218 56/10654 2.2471947736429115e-16 2.1093668275261464e-15 8.058361609344055e-16 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/51009/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/9861/5698/5692/5713/5710/5719/6233/27248/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 55 Human_cytomegalovirus R-HSA-166166 MyD88-independent TLR4 cascade 87/5218 99/10654 2.6753620580073775e-16 2.4782301168910444e-15 9.467520856244945e-16 8454/3725/9252/4790/7321/1848/4792/1432/929/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/1326/5601/5606/8737/8767/1849/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/3665/351/330/79155/7867/5602/3656/7189/7311/9641/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/7316/4205/4793/3146/7322/329/23291/6288/6285/5609/1385/5599/353376/148022 87 Human_cytomegalovirus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 87/5218 99/10654 2.6753620580073775e-16 2.4782301168910444e-15 9.467520856244945e-16 8454/3725/9252/4790/7321/1848/4792/1432/929/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/1326/5601/5606/8737/8767/1849/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/3665/351/330/79155/7867/5602/3656/7189/7311/9641/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/7316/4205/4793/3146/7322/329/23291/6288/6285/5609/1385/5599/353376/148022 87 Human_cytomegalovirus R-HSA-9009391 Extra-nuclear estrogen signaling 71/5218 77/10654 3.6031688439560926e-16 3.3158573413661295e-15 1.2667487301421146e-15 5295/2788/374/4893/857/2770/7039/2782/3845/3265/8877/2773/2787/1839/5290/4316/5594/2069/10681/4313/2792/6714/2099/10000/2785/595/2783/2784/2771/7514/2353/255324/801/2791/805/5170/5590/6464/5747/1903/3315/4318/8503/2786/208/1956/858/3480/5595/596/685/54331/2309/59345/207/1027/51764/94235/2100/1950/55970/4314/346562/2793/3320/4846/1385/5296/808/3276/2790 71 Human_cytomegalovirus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 65/5218 69/10654 3.6651856158819256e-16 3.3510268488063317e-15 1.2801844495664143e-15 23165/6782/573/7531/9530/348995/472/57122/3313/23511/3305/23279/259217/23225/3309/9531/3306/27000/9972/23411/8021/6117/3312/55746/51182/3303/6118/5594/3308/10049/3337/10762/9261/79902/9883/2932/6396/129401/3297/4928/5903/55706/7175/4927/6119/57805/3310/7266/8086/3304/5595/81929/9631/116835/545/79023/23636/10808/53371/9532/9688/6767/22824/9529/8480 65 Human_cytomegalovirus R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 54/5218 55/10654 4.53134506223394e-16 4.063779520780501e-15 1.552475579484776e-15 8454/5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/26271/5706/5714/5688/5687/5708/5704/51343/7311/5694/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 54 Human_cytomegalovirus R-HSA-4641257 Degradation of AXIN 54/5218 55/10654 4.53134506223394e-16 4.063779520780501e-15 1.552475579484776e-15 5689/5682/143471/5705/5709/5695/5711/5683/5699/8312/5702/80351/5696/5691/7314/5718/5700/122706/5707/23198/9861/81847/5698/5692/5713/5710/8313/5719/6233/5706/8658/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/5716/5693/5721 54 Human_cytomegalovirus R-HSA-8941858 Regulation of RUNX3 expression and activity 54/5218 55/10654 4.53134506223394e-16 4.063779520780501e-15 1.552475579484776e-15 5689/5682/5705/5709/5695/5711/5683/5699/5702/7040/5696/5691/7314/5718/5700/5707/865/6714/9861/5698/5692/5713/5710/5719/6233/1029/864/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/2033/5716/5693/5721/4193 54 Human_cytomegalovirus R-HSA-177929 Signaling by EGFR 49/5218 49/10654 5.746525103520165e-16 5.120954016301514e-15 1.9563453217180578e-15 5295/374/4893/5335/7039/55824/6456/6868/30011/2885/8874/3845/3265/10252/5829/7314/8038/1839/5290/8027/2060/2069/102/6714/9146/6455/1445/6233/29924/255324/5781/6464/5782/5796/998/6654/7311/1956/2549/10253/685/26018/58513/7316/1950/867/5774/10254/6457 49 Human_cytomegalovirus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 83/5218 94/10654 6.918431661438341e-16 6.126510553022128e-15 2.3404955835782802e-15 8454/3725/9252/4790/7321/1848/4792/1432/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/1326/5601/5606/8737/8767/1849/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5608/4791/3665/351/330/7098/79155/7867/5602/3656/7189/7311/9641/6416/5595/5516/1147/1845/6885/5604/10392/6500/7316/4205/4793/3146/7322/329/23291/6288/6285/5609/1385/5599/148022 83 Human_cytomegalovirus R-HSA-68867 Assembly of the pre-replicative complex 64/5218 68/10654 7.098179756669555e-16 6.246398185869209e-15 2.386295957669831e-15 5689/5682/143471/5705/5709/1869/4174/5695/84515/4998/5711/5683/990/5699/5702/5001/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/4175/5710/5719/6233/4172/5000/4173/5706/5714/51053/5688/5687/5708/81620/1870/5704/7311/5694/4176/5684/5720/5690/5717/9491/10197/7316/10213/4171/1871/5715/5701/5685/5686/5716/5693/5721 64 Human_cytomegalovirus R-HSA-114608 Platelet degranulation 107/5218 129/10654 7.814045048381929e-16 6.833649334237116e-15 2.6106420527774867e-15 2153/7042/5175/3082/29106/5267/7423/3920/374354/2244/7114/3309/3690/2162/87/7040/5874/54863/350/7043/5054/5099/1072/7018/6678/5340/813/7094/7414/10490/83706/7044/7123/6694/3671/7273/22927/1191/3273/27154/226/2335/1/5478/94121/22915/2266/5154/7076/2243/801/805/351/135228/51097/7424/2316/3674/5552/2157/7277/334/10447/335/308/78991/6403/197/81/9948/3481/5473/8407/7450/29789/10916/139322/5005/7422/5004/5196/3827/1950/2621/5216/5768/710/6647/1893/5265/7078/55664/5345/54676/2/948/88/1675/3479/5155/51368/808/213/5660/7057/5627/3700 107 Human_cytomegalovirus R-HSA-5387390 Hh mutants abrogate ligand secretion 57/5218 59/10654 8.491489196247372e-16 7.334979624733926e-15 2.8021640163270307e-15 5689/5682/143471/5705/5709/5695/3549/5711/5683/5699/6400/5702/51009/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/50846/9861/5698/5692/5713/5710/5719/6233/27248/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 57 Human_cytomegalovirus R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 57/5218 59/10654 8.491489196247372e-16 7.334979624733926e-15 2.8021640163270307e-15 6227/6206/1965/6234/27335/6191/8668/6224/8662/26986/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1978/1968/6230/8669/6194/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 57 Human_cytomegalovirus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 53/5218 54/10654 9.133384245808441e-16 7.79382122308987e-15 2.9774541305314926e-15 8454/5689/5682/143471/5705/5709/9978/5695/6790/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/23194/5693/5721 53 Human_cytomegalovirus R-HSA-9604323 Negative regulation of NOTCH4 signaling 53/5218 54/10654 9.133384245808441e-16 7.79382122308987e-15 2.9774541305314926e-15 8454/5689/5682/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/5707/7534/9861/5698/5692/5713/5710/5719/6233/5706/10460/5714/5688/5687/5708/4855/5704/7311/5694/5684/5720/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721 53 Human_cytomegalovirus R-HSA-6798695 Neutrophil degranulation 320/5218 480/10654 9.46556311972662e-16 8.028622212394629e-15 3.0671545682817396e-15 5869/8773/7130/1727/5689/8804/5777/8514/5806/4893/9218/4790/5273/3240/960/7305/1823/57826/1915/3107/203068/5175/383/8836/2268/5211/5908/1460/29108/23385/54509/6280/5788/535/5912/10312/5709/5269/10576/1509/5695/2896/8655/567/290/7133/3106/3417/3043/1667/2548/2204/1432/3920/5683/929/3482/4311/80142/2444/5702/9961/51552/10075/56729/684/6709/160364/441864/8826/9522/1794/4282/2219/3608/3312/387263/2665/1654/2519/5879/51316/1992/5718/3303/58485/2934/80331/161/56888/3579/5707/2358/3848/8972/272/823/427/5594/5787/6727/7414/258010/10533/4257/51209/326624/847/3683/2517/25852/3934/22918/9545/1315/102/84443/4069/965/4973/9861/5870/6556/28988/226/2821/199675/978/55832/968/23601/5713/1/2495/3728/3614/10043/5478/5719/5328/728/5580/3685/302/634/1729/11026/1535/64114/2040/317/23250/401258/5663/7879/8907/2992/1508/28956/10450/7077/1828/3903/23352/7276/83858/10159/1938/1650/338339/3684/3163/54472/101/3577/79169/2215/55860/10549/2760/5864/4318/3958/963/79980/23317/5836/53917/6993/6616/5329/966/5611/1116/527/6279/6515/11322/4048/353/6286/5337/210/10092/170482/5795/6793/197/140885/3310/5708/3615/11314/138050/23218/820/51143/4860/6386/6402/5473/3326/10857/55004/10097/3916/53831/240/10383/387/81619/683/196527/80184/3304/2547/8673/10493/53916/114790/22931/1778/10694/2512/3837/10890/5036/8621/5005/11333/5315/8876/23197/1991/10120/7520/5717/2919/5004/221/9725/2357/10213/6278/5768/1471/9588/7415/3146/4353/5701/9342/6836/8649/5265/3320/5686/388697/391/175/5873/1088/57126/1143/23071/5878/2683/11031/5646/948/1520/945/1675/7226/719/93100/47/79895/5906/89777/100049587/81567/10855/3687/353376/84418/7097/5660/2212/1536/8987/10970/3689/961/2207/5724/51382/2950/718/5223 320 Human_cytomegalovirus R-HSA-1226099 Signaling by FGFR in disease 60/5218 63/10654 1.1851068680200842e-15 9.991799222588495e-15 3.817142197026555e-15 5295/4893/11052/2250/5335/9530/613/5431/6776/5435/5433/11064/5439/2264/2885/9846/2252/2253/3845/3265/7750/8805/5290/8823/8074/2260/5438/2249/2248/399687/2247/2246/2251/6777/1523/2963/5434/5436/6774/2263/6772/2962/6654/11160/2549/5432/22916/8822/5440/5430/8817/5441/2254/4686/26281/10818/2261/5437/2255/27006 60 Human_cytomegalovirus R-HSA-73856 RNA Polymerase II Transcription Termination 63/5218 67/10654 1.3733277783600134e-15 1.1509794713874399e-14 4.397058237731622e-15 8683/6431/84271/51585/199746/81608/1477/65109/9877/7919/53981/6432/8563/6430/134353/11051/80145/8106/22794/9785/11338/4116/1478/51213/10250/26097/51362/23283/6636/10914/57187/79228/84324/6635/6428/10212/6637/55110/84321/6429/10898/10569/9295/51692/9939/6426/22916/1479/10921/79869/29894/4686/8189/10978/7307/9984/10189/6634/9775/84248/6427/55339/6628 63 Human_cytomegalovirus R-HSA-72649 Translation initiation complex formation 56/5218 58/10654 1.6849328816239637e-15 1.3714292729076829e-14 5.239237129603963e-15 6227/6206/1965/6234/27335/6191/8668/6224/8662/26986/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1968/6230/8669/6194/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 56 Human_cytomegalovirus R-HSA-72702 Ribosomal scanning and start codon recognition 56/5218 58/10654 1.6849328816239637e-15 1.3714292729076829e-14 5.239237129603963e-15 6227/6206/1965/6234/27335/6191/8668/6224/8662/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1968/6230/8669/6194/1983/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 56 Human_cytomegalovirus R-HSA-2871837 FCERI mediated NF-kB activation 74/5218 82/10654 1.6850657969675366e-15 1.3714292729076829e-14 5.239237129603963e-15 8454/5689/4790/5682/7321/143471/5705/5709/5695/4792/5711/5683/5699/5702/7334/3551/5696/5691/7314/257397/5718/8945/5700/122706/5707/23198/23118/10892/8517/5970/9861/5588/5698/5692/5713/5710/10454/5719/6233/5170/5706/8915/5714/5688/5687/4067/5708/7189/5704/7311/5694/997/1147/5684/5720/6885/84433/5690/5717/9491/6500/10197/7316/10213/7322/5715/5701/23291/5685/5686/5716/5693/5721/2207 74 Human_cytomegalovirus R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 74/5218 82/10654 1.6850657969675366e-15 1.3714292729076829e-14 5.239237129603963e-15 10844/440145/7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/80097/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/728642/9738/1639/55722/4957/5566/7283/22919/984/10426/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 74 Human_cytomegalovirus R-HSA-380287 Centrosome maturation 74/5218 82/10654 1.6850657969675366e-15 1.3714292729076829e-14 5.239237129603963e-15 10844/440145/7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/80097/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/728642/9738/1639/55722/4957/5566/7283/22919/984/10426/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 74 Human_cytomegalovirus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 47/5218 47/10654 2.418156581264463e-15 1.9567611875979103e-14 7.475366080012951e-15 8454/79718/892/3091/9978/9759/9612/4609/22938/1387/6907/9794/388585/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/7091/8850/3066/6233/7089/7090/10046/1024/10014/26508/7088/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 47 Human_cytomegalovirus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 62/5218 66/10654 2.654398467515114e-15 2.135653167006446e-14 8.158782658046455e-15 5689/5682/64344/7321/3091/143471/5705/5709/9978/5695/5711/5683/5699/126374/7428/5702/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/112399/84962/5706/5714/5688/5687/5708/5704/7311/2034/5694/5684/5720/5690/5717/9491/10197/7316/10213/8994/7322/5715/5701/5685/5686/8453/5716/54583/5693/5721 62 Human_cytomegalovirus R-HSA-69541 Stabilization of p53 55/5218 57/10654 3.3410608486415237e-15 2.672848678913219e-14 1.0211017306553938e-14 5689/5682/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/51230/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721/4193 55 Human_cytomegalovirus R-HSA-180534 Vpu mediated degradation of CD4 51/5218 52/10654 3.705739009691681e-15 2.866857431673564e-14 1.0952184117712256e-14 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/920/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_cytomegalovirus R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 51/5218 52/10654 3.705739009691681e-15 2.866857431673564e-14 1.0952184117712256e-14 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_cytomegalovirus R-HSA-69610 p53-Independent DNA Damage Response 51/5218 52/10654 3.705739009691681e-15 2.866857431673564e-14 1.0952184117712256e-14 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_cytomegalovirus R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 51/5218 52/10654 3.705739009691681e-15 2.866857431673564e-14 1.0952184117712256e-14 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_cytomegalovirus R-HSA-72165 mRNA Splicing - Minor Pathway 51/5218 52/10654 3.705739009691681e-15 2.866857431673564e-14 1.0952184117712256e-14 6633/6431/4904/51639/23450/5431/5435/5433/9416/8233/23020/5439/9410/10907/10262/6432/83443/10081/5438/9343/6636/2963/6635/5434/6632/24148/154007/5436/6637/55954/57819/2962/6426/5432/22916/23451/5440/55599/5430/85437/11325/5441/79622/10594/4686/5437/11066/6634/6427/10992/6628 51 Human_cytomegalovirus R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 51/5218 52/10654 3.705739009691681e-15 2.866857431673564e-14 1.0952184117712256e-14 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/2932/5698/5692/5713/595/5710/5719/6233/1019/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_cytomegalovirus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 70/5218 77/10654 3.915219198171609e-15 3.0123653721451504e-14 1.1508064482402602e-14 5689/5682/51807/63943/347688/143471/10381/5705/5709/5695/5711/7846/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/983/9861/5698/5692/5713/10376/5710/7157/5719/6233/84617/51512/10382/7277/5706/9133/891/5714/5688/5687/5708/22919/5704/3326/7311/10383/5347/84790/5694/7280/5684/5720/5690/5717/9491/10197/7316/10213/1026/5715/5701/5685/3320/5686/5716/5693/5721 70 Human_cytomegalovirus R-HSA-5654738 Signaling by FGFR2 67/5218 73/10654 4.631848015490266e-15 3.544370655331682e-14 1.3540471029265022e-14 5295/4893/2250/5335/5431/5435/5433/8569/5439/7072/2885/7073/5518/2252/2253/3845/3265/7314/5515/5290/8823/5594/8074/5438/3185/2249/6714/2248/4670/2247/6233/2246/2251/5781/5725/2963/5434/6464/5436/673/2263/2962/6654/7311/2549/5432/22916/5595/5516/8822/10253/5440/23543/5430/3178/8817/5441/2254/4686/7316/26281/10818/867/5437/2255/27006/3187 67 Human_cytomegalovirus R-HSA-199992 trans-Golgi Network Vesicle Budding 66/5218 72/10654 8.743339862477773e-15 6.654390554793894e-14 2.542160267269498e-14 27131/8773/8906/162/1176/27243/5286/1212/1174/1785/8546/7037/3482/408/6456/7164/3312/1362/26258/25977/10618/6643/10053/6810/55330/8301/9146/8729/4074/2495/388552/152503/6844/54885/1213/2580/1211/23431/8907/351/84062/9685/9179/9026/8775/9829/8905/51429/64746/8673/23557/2512/164/130340/6272/2804/2647/7163/286451/9698/5878/81567/10717/6845/375/4952 66 Human_cytomegalovirus R-HSA-1227986 Signaling by ERBB2 49/5218 50/10654 1.5008102889173747e-14 1.1300218645966115e-13 4.3169944139419e-14 5295/4893/5335/26469/5578/2064/5753/145957/2534/4145/9542/2885/3845/3265/7314/1839/5290/2065/2069/9101/6714/10000/6233/7525/5580/1729/6464/5782/10193/3084/2886/208/6654/10718/7311/387/1956/2549/11140/8065/685/10273/207/7316/1950/51072/3320/2066/5581 49 Human_cytomegalovirus R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 49/5218 50/10654 1.5008102889173747e-14 1.1300218645966115e-13 4.3169944139419e-14 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 49 Human_cytomegalovirus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 105/5218 129/10654 1.8484512400869175e-14 1.384371992575734e-13 5.2886818795319986e-14 8454/3725/9252/4790/7321/1848/1785/10333/4792/1432/929/3654/51135/6196/1759/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/1326/5601/5606/11213/8737/8767/5336/1849/29110/5594/4214/23118/841/8517/5528/7323/5970/7096/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/3665/351/3684/330/79155/8651/26052/7867/5602/3656/57162/695/7189/7311/9641/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/4205/4793/3146/7322/329/23291/6288/6285/5609/948/1385/5599/353376/7097/57161/3689/148022 105 Human_cytomegalovirus R-HSA-166520 Signaling by NTRKs 86/5218 101/10654 2.498361760568514e-14 1.8612134173970727e-13 7.110347310779787e-14 5295/627/9252/4893/5335/5291/1848/1785/5605/5898/1432/2534/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5879/5515/5607/161/5290/3667/1849/5594/5528/1795/9261/6714/5519/5598/4208/4909/4914/6195/1213/1211/5600/1175/6300/5781/4908/1173/5800/6464/2904/7074/160/673/6774/26052/7867/2889/6654/5900/387/2549/1020/4916/7529/5595/25759/5516/1845/4915/5604/5045/4205/57498/10818/53358/4803/1398/1385/5906/8851/5296/581 86 Human_cytomegalovirus R-HSA-446652 Interleukin-1 family signaling 112/5218 140/10654 2.5529370296521798e-14 1.891860704079089e-13 7.22742837757487e-14 8454/834/5689/5777/4790/5682/26469/5783/8878/143471/5705/5709/9978/5695/4792/3606/5711/4088/5683/5699/5702/3654/51135/7334/3551/5696/5691/7314/3596/257397/5718/8945/1326/90865/11213/5700/122706/5707/8767/29110/23198/23118/8517/3565/5970/9861/5698/5692/5713/5710/10454/5719/6233/7850/5781/5608/4791/3557/351/5782/54472/5706/79155/6774/5714/3552/5688/5687/5708/3656/57162/5771/7189/5704/7311/240/5694/6416/3554/3556/1147/5778/5684/5720/6885/5604/4215/10392/5690/3553/5717/9491/6500/25930/10197/4615/7316/10213/4793/3146/5715/5701/23291/5685/5686/6288/6285/5716/5599/57161/5693/5721 112 Human_cytomegalovirus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 48/5218 49/10654 3.018137229128119e-14 2.224888596132142e-13 8.499686547723718e-14 9134/57060/2810/1869/6790/25904/1647/8900/55571/55835/57472/144455/85456/29883/1263/7027/7832/898/5934/890/10769/983/7157/7029/5325/79733/1820/4869/4850/891/5111/246175/4848/23019/1874/1017/25946/4849/1027/9337/1026/5933/28984/2033/995/10498/581/3276 48 Human_cytomegalovirus R-HSA-5610787 Hedgehog 'off' state 94/5218 113/10654 3.1816504536462134e-14 2.3332103326738895e-13 8.913505382747892e-14 8454/5689/57728/5682/1452/51684/143471/10381/5705/5709/9978/5695/107/5711/7846/5683/5699/5702/83737/5696/5691/7314/5718/8945/79659/5700/122706/5707/5567/23198/112/5573/2737/5727/8650/111/9861/2932/5698/5692/5713/10376/5710/5719/6233/23322/196883/115/84617/54903/10382/5568/7277/5706/113/5714/5566/2736/5688/5687/5708/5577/5704/7311/10383/84790/5694/7280/109/5684/5720/55081/2735/5575/6608/5690/5717/9491/6500/114/10197/108/7316/10213/2778/5715/5701/5576/5685/5686/5716/8481/5693/5721 94 Human_cytomegalovirus R-HSA-9612973 Autophagy 98/5218 119/10654 3.264640529560401e-14 2.3816652153476916e-13 9.098616365450587e-14 51652/5563/2670/65018/1459/1915/27243/9140/8878/1460/53632/84938/5116/115201/9474/8655/1457/51271/3043/3920/10325/29082/9776/55054/55062/2475/84557/10670/3312/11315/64121/92421/7314/137492/64422/139341/25978/51160/60673/9821/51422/7249/10533/10013/91782/79720/440738/6714/8408/84971/6233/30849/57521/140735/28956/7405/389541/79065/22863/58528/7416/26100/64223/5571/128866/6009/3326/55004/7311/5562/93343/11345/55626/7251/5564/5565/7248/11337/10452/1080/64419/153129/7316/83734/11152/5289/8678/56993/10226/8649/3320/81631/10542/23710/54543/200894/7431/23192 98 Human_cytomegalovirus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 83/5218 97/10654 3.9480983385863624e-14 2.86542394882969e-13 1.0946707818869405e-13 8454/3725/9252/4790/1848/4792/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/30849/5608/4791/3665/351/8411/79155/7867/5602/3656/57162/7189/7311/6416/51284/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/4205/5289/4793/3146/23291/6288/6285/5609/1385/5599/353376/57161/148022 83 Human_cytomegalovirus R-HSA-5655253 Signaling by FGFR2 in disease 43/5218 43/10654 4.276872512949441e-14 3.088121281145032e-13 1.1797472896718834e-13 5295/4893/2250/5335/5431/5435/5433/5439/2885/2252/2253/3845/3265/5290/8823/8074/5438/2249/2248/2247/2246/2251/2963/5434/5436/2263/2962/6654/2549/5432/22916/8822/5440/5430/8817/5441/2254/4686/26281/10818/5437/2255/27006 43 Human_cytomegalovirus R-HSA-170834 Signaling by TGF-beta Receptor Complex 66/5218 73/10654 4.7508834419788096e-14 3.4128795338296755e-13 1.3038138769340344e-13 892/7321/25805/4738/9372/8239/9612/4609/4089/22938/23327/4088/5499/1030/9110/7040/904/7314/5054/7027/6497/51592/50848/7323/6667/4092/11171/7046/5494/2280/9958/9040/6233/7514/1025/7029/57530/5500/4221/5590/3726/5501/1024/23645/8812/1874/142/4087/7048/7311/387/57154/51377/10273/5045/50855/23370/64750/7316/1875/9611/5933/867/3065/56288/25937 66 Human_cytomegalovirus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 80/5218 93/10654 6.155395834399828e-14 4.3771703711287663e-13 1.6721995063148923e-13 8454/3725/9252/4790/1848/4792/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/3665/351/79155/7867/5602/3656/57162/7189/7311/6416/51284/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/4205/4793/3146/23291/6288/6285/5609/1385/5599/353376/57161/148022 80 Human_cytomegalovirus R-HSA-975155 MyD88 dependent cascade initiated on endosome 80/5218 93/10654 6.155395834399828e-14 4.3771703711287663e-13 1.6721995063148923e-13 8454/3725/9252/4790/1848/4792/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/3665/351/79155/7867/5602/3656/57162/7189/7311/6416/51284/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/4205/4793/3146/23291/6288/6285/5609/1385/5599/353376/57161/148022 80 Human_cytomegalovirus R-HSA-5617833 Cilium Assembly 150/5218 201/10654 6.227470690801704e-14 4.406170217411457e-13 1.683278245437541e-13 55763/57728/79738/1260/79867/7531/11190/203068/54801/51807/1258/85302/347688/1262/79441/10381/5116/5048/10576/22832/60412/192668/8655/83658/6010/89891/9702/132320/7846/7840/11064/84902/2847/5518/55835/23332/93323/79659/10575/1454/9321/10013/54806/9727/91147/983/79959/5310/8729/10376/10540/11336/117177/57545/26005/54930/54820/23322/378/56623/1453/9793/4218/140735/57576/6102/84617/11258/22981/8636/54903/80776/3842/7532/55125/10382/6753/121441/7277/55112/26146/9814/23354/146057/9738/1639/55722/4957/50807/5566/7283/22919/27077/22994/4867/5311/1069/5577/10383/5347/403/84790/22948/80184/22897/5108/261734/57787/7280/10806/9657/1778/55770/23265/115106/10694/22995/55559/55081/10142/6608/10640/51134/95681/79989/7203/1781/80321/8766/79598/149371/10121/347240/84131/6950/55212/3320/79600/10733/4751/80254/200894/26123/54536/9662/55142/8195/8481/51259/55755 150 Human_cytomegalovirus R-HSA-5358346 Hedgehog ligand biogenesis 60/5218 65/10654 6.700816053462121e-14 4.717374501637333e-13 1.802166843852181e-13 5689/5682/143471/5705/5709/5695/3549/5711/5683/5699/6400/5702/6868/51009/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/50846/9861/5698/5692/5713/5710/5719/6233/27248/5706/84447/5714/5688/5687/5708/5704/7311/147111/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721/5034 60 Human_cytomegalovirus R-HSA-5358351 Signaling by Hedgehog 117/5218 149/10654 8.102392584246853e-14 5.675705850059488e-13 2.1682757845248195e-13 8454/5689/57728/5682/22873/1452/51684/143471/10381/5705/8452/5709/9978/5695/107/3549/5711/7846/5683/408/5699/6400/5702/83737/6868/51009/6469/5696/5691/7314/5718/8945/79659/339745/5700/122706/5707/5567/10956/23198/112/5573/2737/5727/8650/111/50846/9861/8405/2932/5698/5692/5713/10376/5710/5719/6233/27248/23322/196883/115/84617/54903/10382/5568/409/79577/7277/5706/113/84447/5714/5566/2736/5688/5687/5708/5577/5704/7311/147111/10383/84790/5694/7280/109/57154/5684/5720/55081/2735/5575/6608/5690/5717/9491/6500/114/10197/108/64750/132884/7316/10213/2778/7415/5715/5701/5576/5685/5686/5716/2121/8481/5693/5721/5034 117 Human_cytomegalovirus R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/5218 52/10654 1.0130020849914671e-13 7.060925424098939e-13 2.697467771915788e-13 5689/5682/143471/472/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Human_cytomegalovirus R-HSA-4086400 PCP/CE pathway 79/5218 92/10654 1.0906452357890677e-13 7.527590647014742e-13 2.875746725945375e-13 5689/5579/5682/5578/1212/5582/143471/5705/5709/5695/5881/5711/5683/5699/5702/1855/163/5696/5691/4920/7314/5879/5718/161/5700/122706/5707/1856/8322/23198/7471/9861/5698/5880/5692/5713/5710/5719/6233/7474/1857/1213/1211/7855/1175/1173/144165/409/5706/160/5714/5688/5687/4919/5708/5704/7311/387/5694/57154/5684/5720/5690/5717/9491/50855/10197/64750/7316/10213/5216/5715/5701/5685/5686/5716/5693/5721/6259 79 Human_cytomegalovirus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 79/5218 92/10654 1.0906452357890677e-13 7.527590647014742e-13 2.875746725945375e-13 8454/3725/9252/4790/1848/4792/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/351/79155/7867/5602/3656/57162/7189/7311/6416/51284/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/4205/4793/3146/23291/6288/6285/5609/1385/5599/353376/57161/148022 79 Human_cytomegalovirus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 81/5218 95/10654 1.224768738120562e-13 8.371234870260927e-13 3.1980420295329955e-13 8454/3725/9252/4790/1848/10333/4792/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/11213/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/79155/8651/7867/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/4205/4793/3146/23291/6288/6285/5609/948/1385/5599/7097/57161 81 Human_cytomegalovirus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 81/5218 95/10654 1.224768738120562e-13 8.371234870260927e-13 3.1980420295329955e-13 8454/3725/9252/4790/1848/10333/4792/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/11213/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/79155/8651/7867/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/4205/4793/3146/23291/6288/6285/5609/948/1385/5599/7097/57161 81 Human_cytomegalovirus R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 49/5218 51/10654 1.9995199860988382e-13 1.3535212213592136e-12 5.170823445832522e-13 5689/5682/143471/5705/5709/5695/5711/4946/5683/5699/5702/5696/5691/5718/1728/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/5706/4947/5714/5688/5687/5708/4953/5704/5694/5684/5720/5690/51686/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 49 Human_cytomegalovirus R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 49/5218 51/10654 1.9995199860988382e-13 1.3535212213592136e-12 5.170823445832522e-13 6227/6206/1965/6234/27335/6191/8668/6224/8662/6202/6218/3921/8665/6208/6203/8666/6222/8667/6231/8663/8894/6207/6233/51386/6188/1968/6230/8669/6194/6232/6193/6210/6229/6205/6235/6223/8664/6187/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 49 Human_cytomegalovirus R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 80/5218 94/10654 2.151283081148836e-13 1.4492854441423738e-12 5.53666912348051e-13 10844/440145/7531/11190/203068/54801/51807/347688/79441/10381/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/80097/10376/10540/54930/54820/1453/9793/84617/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/10426/22994/1069/5577/10383/5347/84790/80184/22897/5108/7280/10806/1778/115106/4926/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 80 Human_cytomegalovirus R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 55/5218 59/10654 2.594395412296493e-13 1.7394803526254581e-12 6.645293512198035e-13 5689/5682/143471/5705/5709/5695/84515/4998/5711/5683/990/5699/5702/5001/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5000/5706/5714/51053/5688/5687/5708/81620/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 55 Human_cytomegalovirus R-HSA-1852241 Organelle biogenesis and maintenance 206/5218 296/10654 2.636624474078729e-13 1.7594157627975594e-12 6.721452263677878e-13 55763/5563/57728/79738/1260/79867/55735/79718/7531/11190/203068/54801/51807/1258/85302/347688/1262/79441/53632/10381/5116/3313/5048/10576/5469/10989/22832/60412/192668/8655/83658/6010/89891/9702/132320/1432/1387/25813/7846/7840/6907/2101/11064/84902/4509/2847/10499/23054/5518/1386/55835/85441/3054/23332/7019/93323/96764/79659/10575/1454/9321/23408/51422/10013/54806/9727/91147/54927/983/64784/79959/5310/4208/6604/8729/10376/4508/10540/11336/117177/57545/26005/54930/54820/23322/6742/378/56623/5600/1453/6300/801/9793/4218/133522/140735/57576/805/6102/84617/5442/11258/22981/8636/54903/80776/3842/3418/7532/55125/10382/6753/23410/121441/7277/55112/26146/8834/9814/4209/23354/2553/146057/9738/1639/55722/4957/50807/5566/5571/7283/22919/27077/22994/4867/5311/6648/1069/5577/10383/5347/403/84790/22948/80184/22897/5564/23373/5565/5108/261734/57787/7280/10806/9657/1778/55770/23265/139322/115106/10694/22995/55559/8841/55081/10142/6608/10640/51134/95681/200186/79989/7203/1781/80321/8766/9611/23409/79598/54205/149371/10121/347240/84131/6950/55212/3320/79600/10733/6256/4751/10498/80254/1385/200894/26123/808/54536/9662/55142/8195/8648/8481/51259/55755/10891 206 Human_cytomegalovirus R-HSA-8868773 rRNA processing in the nucleus and cytosol 145/5218 195/10654 2.685664539128098e-13 1.7836866373077182e-12 6.814173681700389e-13 6158/5393/6138/6227/6206/6234/6191/6128/6132/6129/23404/55226/6176/84135/27043/6224/6146/6154/6202/51096/6169/55272/6175/6218/6173/6167/28987/116832/23481/6156/117246/6143/6139/79159/23160/26168/11340/3921/10607/11103/51388/6208/6170/22984/10813/6203/51504/54433/6147/27292/6222/1454/56902/51602/6134/6155/6231/6142/23521/10171/5822/6207/10969/6233/6188/79707/1453/4691/23016/118460/200916/6122/6230/2091/55651/55127/6194/6166/8780/6136/6125/4839/6232/90459/6160/65083/6193/10200/6210/6229/6205/9790/55131/140801/6235/6181/55759/705/7311/6223/25873/51010/26354/56915/51202/9045/6187/6168/6157/6137/22894/84946/6144/9349/55813/4736/22803/51121/6159/6217/81887/6152/57050/51065/6141/6123/55781/6164/6209/11224/6165/6130/6204/1736/6228/51013/6124/83732/6189/6135/6201/6161/54512/6133/9188 145 Human_cytomegalovirus R-HSA-5619084 ABC transporter disorders 68/5218 77/10654 3.01727969974767e-13 1.9945210409599625e-12 7.619619108332394e-13 5689/5682/143471/91319/5705/5709/5695/64240/5711/5683/5699/6400/5702/51009/5696/5691/7314/5718/5700/122706/5707/10956/79139/91445/64241/23198/9861/5698/5692/5713/5710/5719/10613/6233/27248/10058/6048/5706/19/335/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/1244/7316/10213/7415/5715/5701/5685/5686/5826/5716/21/5693/5721 68 Human_cytomegalovirus R-HSA-187037 Signaling by NTRK1 (TRKA) 70/5218 80/10654 3.788171505411205e-13 2.4924044297284934e-12 9.521670630915524e-13 5295/9252/4893/5335/5291/1848/1785/5605/5898/1432/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5515/5607/161/5290/3667/1849/5594/5528/9261/6714/5519/5598/4208/4914/6195/1213/1211/5600/1175/6300/1173/6464/160/673/6774/26052/7867/2889/6654/5900/387/7529/5595/25759/5516/1845/4915/5604/4205/57498/10818/53358/4803/1398/1385/5906/5296 70 Human_cytomegalovirus R-HSA-180585 Vif-mediated degradation of APOBEC3G 51/5218 54/10654 4.820902094959689e-13 3.128032327052186e-12 1.1949944072395835e-12 5689/5682/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/60489/5706/5714/5688/5687/5708/5704/7311/5694/5684/8065/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_cytomegalovirus R-HSA-8848021 Signaling by PTK6 51/5218 54/10654 4.820902094959689e-13 3.128032327052186e-12 1.1949944072395835e-12 4893/1796/5770/2909/9021/27043/3091/2064/5753/145957/9542/9564/3845/3265/5829/7314/5879/120892/1839/2065/2069/898/202559/5921/6421/595/6233/1019/10657/6774/2908/3084/10718/7311/2034/387/1956/63916/1017/685/207/55620/1027/10457/7316/1950/867/2066/1398/9844/10656 51 Human_cytomegalovirus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 51/5218 54/10654 4.820902094959689e-13 3.128032327052186e-12 1.1949944072395835e-12 4893/1796/5770/2909/9021/27043/3091/2064/5753/145957/9542/9564/3845/3265/5829/7314/5879/120892/1839/2065/2069/898/202559/5921/6421/595/6233/1019/10657/6774/2908/3084/10718/7311/2034/387/1956/63916/1017/685/207/55620/1027/10457/7316/1950/867/2066/1398/9844/10656 51 Human_cytomegalovirus R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 138/5218 185/10654 6.727830738068047e-13 4.345314531743033e-12 1.6600296992529079e-12 6158/5393/6138/6227/6206/6234/6191/6128/6132/6129/23404/6176/84135/27043/6224/6146/6154/6202/51096/6169/55272/6175/6218/6173/6167/28987/116832/23481/6156/117246/6143/6139/79159/23160/26168/11340/3921/10607/11103/51388/6208/6170/22984/10813/6203/6147/6222/1454/56902/51602/6134/6155/6231/6142/23521/10171/5822/6207/10969/6233/6188/79707/1453/4691/23016/118460/200916/6122/6230/2091/55127/6194/6166/8780/6136/6125/6232/90459/6160/65083/6193/10200/6210/6229/6205/9790/55131/140801/6235/6181/55759/705/7311/6223/25873/51010/26354/56915/51202/9045/6187/6168/6157/6137/22894/84946/6144/9349/55813/4736/22803/51121/6159/6217/81887/6152/57050/51065/6141/6123/55781/6164/6209/11224/6165/6130/6204/6228/51013/6124/83732/6189/6135/6201/6161/54512/6133/9188 138 Human_cytomegalovirus R-HSA-1632852 Macroautophagy 80/5218 95/10654 7.092692910632977e-13 4.5600509672014756e-12 1.742064925418626e-12 51652/5563/65018/1459/27243/9140/8878/1460/53632/84938/115201/9474/8655/1457/10325/29082/9776/55054/55062/2475/84557/10670/3312/64121/92421/7314/64422/139341/25978/60673/9821/51422/7249/10533/91782/440738/6714/8408/84971/6233/30849/57521/140735/28956/7405/389541/79065/22863/58528/7416/26100/64223/5571/128866/6009/55004/7311/5562/11345/55626/5564/5565/7248/11337/10452/64419/153129/7316/83734/11152/5289/8678/56993/10226/8649/81631/10542/23710/54543/23192 80 Human_cytomegalovirus R-HSA-9614085 FOXO-mediated transcription 59/5218 65/10654 7.184645769326589e-13 4.5981732923690176e-12 1.7566287024525776e-12 2308/857/2290/65018/57060/356/10971/7295/2810/84676/4089/1647/1387/4088/10628/4801/3630/56729/23411/2538/7534/847/5934/3484/5443/8850/10000/3066/604/2645/5105/7532/4303/23410/4287/4800/901/9314/10370/2908/6794/4852/6648/4087/208/25942/7529/27113/2309/10018/4802/207/1027/6720/1649/1026/2033/3065/10891 59 Human_cytomegalovirus R-HSA-169911 Regulation of Apoptosis 50/5218 53/10654 9.34992510589465e-13 5.917907996325602e-12 2.2608036678546522e-12 5689/5682/4976/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Human_cytomegalovirus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 73/5218 85/10654 9.414853630518004e-13 5.917907996325602e-12 2.2608036678546522e-12 8454/3725/9252/4790/1848/4792/1432/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/81793/79155/7867/5602/3656/57162/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/4615/7100/7316/4205/4793/3146/23291/6288/6285/5609/1385/5599/57161 73 Human_cytomegalovirus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 73/5218 85/10654 9.414853630518004e-13 5.917907996325602e-12 2.2608036678546522e-12 8454/3725/9252/4790/1848/4792/1432/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/81793/79155/7867/5602/3656/57162/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/4615/7100/7316/4205/4793/3146/23291/6288/6285/5609/1385/5599/57161 73 Human_cytomegalovirus R-HSA-975871 MyD88 cascade initiated on plasma membrane 73/5218 85/10654 9.414853630518004e-13 5.917907996325602e-12 2.2608036678546522e-12 8454/3725/9252/4790/1848/4792/1432/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/81793/79155/7867/5602/3656/57162/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/4615/7100/7316/4205/4793/3146/23291/6288/6285/5609/1385/5599/57161 73 Human_cytomegalovirus R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 43/5218 44/10654 9.849140424011085e-13 6.109070359915246e-12 2.3338329499975258e-12 834/79370/55367/472/1387/51499/8738/7159/637/27166/23368/332/64065/8797/7157/1121/604/63970/839/317/5875/55240/5366/84883/147923/843/94241/8626/7161/10397/8795/665/27113/9540/8793/835/58484/3486/355/8794/124446/5876/581 43 Human_cytomegalovirus R-HSA-69231 Cyclin D associated events in G1 43/5218 44/10654 9.849140424011085e-13 6.109070359915246e-12 2.3338329499975258e-12 8454/5925/1869/5753/1031/3717/5520/28227/1030/5518/7314/5515/25/7027/5934/6714/5519/6502/595/896/6233/7029/1163/1019/1029/4331/4067/1874/1870/7311/5516/894/902/1027/6500/7316/1875/1026/5933/1871/1021/1022/1028 43 Human_cytomegalovirus R-HSA-69236 G1 Phase 43/5218 44/10654 9.849140424011085e-13 6.109070359915246e-12 2.3338329499975258e-12 8454/5925/1869/5753/1031/3717/5520/28227/1030/5518/7314/5515/25/7027/5934/6714/5519/6502/595/896/6233/7029/1163/1019/1029/4331/4067/1874/1870/7311/5516/894/902/1027/6500/7316/1875/1026/5933/1871/1021/1022/1028 43 Human_cytomegalovirus R-HSA-5658442 Regulation of RAS by GAPs 61/5218 68/10654 1.040298605252536e-12 6.424300158752503e-12 2.454259405743518e-12 5689/4893/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/3845/3265/4763/5696/5691/7314/5718/5700/122706/5707/23198/5921/9861/5698/5692/5713/5710/5719/6233/200734/9462/5706/84078/5714/5688/5687/5708/5704/7311/5694/5684/5720/153090/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/399473/5693/5721/161742 61 Human_cytomegalovirus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 68/5218 78/10654 1.2263795053638644e-12 7.540359578831096e-12 2.8806248091975855e-12 3443/3442/4790/7321/9140/79132/9474/4792/3093/1387/64135/83737/7187/1540/3551/7314/3445/8737/29110/4214/9636/841/8517/3444/7323/5970/23586/7128/3451/3448/3661/3439/51191/6233/10010/55593/84282/8772/3452/4791/3446/3665/351/54476/7706/843/3440/9246/7189/7311/7318/5094/9641/3456/1147/3441/7186/57506/3449/7316/4793/3146/7322/2033/6288/54941/6285/5300 68 Human_cytomegalovirus R-HSA-450294 MAP kinase activation 58/5218 64/10654 1.3407278211826233e-12 8.207585966196233e-12 3.1355236458778973e-12 8454/3725/9252/4790/1848/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/23118/8517/5528/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/79155/7867/5602/3656/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/7316/4205/23291/5609/1385/5599 58 Human_cytomegalovirus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 46/5218 48/10654 1.52966332867332e-12 9.32366219381833e-12 3.5618954702759927e-12 5295/5777/1437/5291/6776/3558/3717/2534/2885/9846/1399/7314/3635/5290/1439/7534/3718/3567/6233/7525/7409/6777/5781/3562/6464/1438/6850/5566/8503/2889/4067/29760/3636/6654/3716/7311/5293/3561/3568/7316/3560/3055/867/1398/5296/3559 46 Human_cytomegalovirus R-HSA-420499 Class C/3 (Metabotropic glutamate/pheromone receptors) 38/5218 38/10654 1.5477882752367312e-12 9.39347367040223e-12 3.588565374981714e-12 50833/5726/2550/50832/259294/2912/259295/9568/2911/2914/259296/259289/50835/338398/2916/259293/54429/222545/80835/50840/2913/2918/50838/83756/259286/259287/50836/846/259290/80834/259292/50834/259285/2917/50831/50839/50837/2915 38 Human_cytomegalovirus R-HSA-429914 Deadenylation-dependent mRNA decay 52/5218 56/10654 1.8154777918720423e-12 1.0970784253029338e-11 4.191141412453642e-12 5393/80153/23404/26986/28960/219988/25904/1973/10767/55571/11340/57472/85456/29883/80349/51690/11157/1981/1977/23016/118460/9924/23644/5073/27258/4850/9652/255967/57819/246175/4848/23019/23658/1975/51010/56915/1974/167227/22894/1656/27257/4849/25804/10605/9337/55802/51013/196513/9775/54464/6499/54512 52 Human_cytomegalovirus R-HSA-190236 Signaling by FGFR 74/5218 87/10654 1.8521904169063982e-12 1.1144803876086363e-11 4.2576216960826345e-12 5295/4893/2250/5335/5431/5435/5433/8569/9965/5439/2264/7072/2885/7073/5518/2252/2253/3845/3265/7314/5515/5290/8823/5594/8074/2260/5438/3185/2249/6714/2248/4670/2247/6233/2246/2251/200734/5781/5725/2963/5434/6464/5436/673/2263/2962/9365/6654/7311/2549/5432/22916/5595/5516/8822/10253/5440/23543/5430/3178/8817/5441/2254/4686/7316/26281/10818/2261/867/5437/2255/27006/3187/161742 74 Human_cytomegalovirus R-HSA-5696398 Nucleotide Excision Repair 90/5218 111/10654 2.1435656943149786e-12 1.2843151053597828e-11 4.9064370427545535e-12 2074/10445/5982/6613/7507/5431/5435/9978/5433/10980/2965/5439/10987/2067/6612/6117/7334/10714/91603/7314/6118/83444/9557/86/5438/1643/29844/5985/2068/5984/6233/8607/7874/5424/5886/8451/8554/10450/5434/5436/7515/54107/8450/4331/5425/5111/6119/5427/1161/1642/142/2071/1069/7329/51426/2873/7311/60/8533/5983/10038/5432/51138/7528/56655/9318/6917/5440/902/27339/5430/57804/5441/7336/2072/7316/5426/7341/5437/10401/2033/2968/56949/5887/9716/5981/1022/8178/50813/7508 90 Human_cytomegalovirus R-HSA-4420097 VEGFA-VEGFR2 Pathway 82/5218 99/10654 2.2640140597251468e-12 1.3507338119038165e-11 5.160174774841882e-12 5295/4893/857/5335/71/5579/5291/5578/1432/2534/3690/5603/2475/8440/9564/3845/3265/8877/5062/5829/5879/5290/5567/10006/5921/1500/9261/6714/10810/10000/3728/7410/5580/7409/3685/3791/3710/1535/5600/6300/801/253260/805/5170/4688/5590/5747/5568/3315/10451/10152/7867/64223/5566/1003/998/208/79109/2185/387/60/5058/63916/25759/558/1495/1499/4690/207/7422/10458/3708/9047/55615/10768/3320/4846/1398/9844/5296/808/1536 82 Human_cytomegalovirus R-HSA-6806003 Regulation of TP53 Expression and Degradation 37/5218 37/10654 3.1717560544660014e-12 1.884317520965456e-11 7.198611342803139e-12 11200/472/639/4194/8900/2475/5518/51230/7314/5515/6446/117584/890/983/5519/10000/900/7157/6233/7874/253260/5170/1029/80196/64223/1616/208/79109/7311/5516/1017/207/7316/55615/9099/5527/4193 37 Human_cytomegalovirus R-HSA-194138 Signaling by VEGF 87/5218 107/10654 3.71828776973548e-12 2.199726546129225e-11 8.403560594139012e-12 5295/4893/857/5335/71/5579/5291/5578/7423/1432/2534/3690/5603/2475/8440/9564/3845/3265/8877/5062/5829/5879/5290/5567/10006/5921/1500/9261/6714/2321/10810/10000/3728/7410/5580/2324/7409/3685/3791/3710/1535/5600/6300/801/253260/805/5170/4688/5590/5747/7424/5568/3315/10451/10152/7867/64223/5566/1003/998/208/79109/2185/387/60/5058/63916/25759/558/1495/1499/4690/207/7422/10458/3708/9047/55615/10768/3320/4846/1398/9844/5228/5296/808/1536 87 Human_cytomegalovirus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 81/5218 98/10654 3.86448284127307e-12 2.2671632668802007e-11 8.661187420572539e-12 8454/3725/9252/4790/1848/10333/4792/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/11213/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/79155/8651/7867/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/4205/4793/3146/23291/6288/6285/5609/948/1385/5599/7097/57161 81 Human_cytomegalovirus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 81/5218 98/10654 3.86448284127307e-12 2.2671632668802007e-11 8.661187420572539e-12 8454/3725/9252/4790/1848/10333/4792/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/11213/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/79155/8651/7867/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/4205/4793/3146/23291/6288/6285/5609/948/1385/5599/7097/57161 81 Human_cytomegalovirus R-HSA-6806834 Signaling by MET 68/5218 79/10654 4.590242969980628e-12 2.681768506943039e-11 1.0245093503647526e-11 5295/3675/4893/5770/10653/3249/5908/3082/1280/1289/3688/3910/1290/6456/30011/2885/3845/3265/1399/7314/5879/3918/5290/8027/2060/284217/9101/6714/9146/6455/2335/64759/84951/6233/5781/1302/6464/85440/5747/382/1277/3912/6774/4233/5795/2889/5771/3913/6654/5867/7311/2549/53916/26018/10048/7316/3915/1301/1281/3673/867/3914/1398/5906/23163/1278/10254/6457 68 Human_cytomegalovirus R-HSA-5632684 Hedgehog 'on' state 72/5218 85/10654 5.671203373355294e-12 3.2996092354067167e-11 1.2605415066483495e-11 5689/5682/22873/1452/51684/143471/5705/8452/5709/9978/5695/3549/5711/5683/408/5699/5702/83737/6469/5696/5691/7314/5718/339745/5700/122706/5707/23198/2737/5727/8650/50846/9861/8405/5698/5692/5713/5710/5719/6233/409/79577/5706/5714/2736/5688/5687/5708/5704/7311/5694/57154/5684/5720/2735/6608/5690/5717/9491/10197/64750/132884/7316/10213/5715/5701/5685/5686/5716/2121/5693/5721 72 Human_cytomegalovirus R-HSA-6804757 Regulation of TP53 Degradation 36/5218 36/10654 6.4989783454882234e-12 3.7656631730236295e-11 1.4385869328761023e-11 11200/472/4194/8900/2475/5518/51230/7314/5515/6446/117584/890/983/5519/10000/900/7157/6233/7874/253260/5170/1029/80196/64223/1616/208/79109/7311/5516/1017/207/7316/55615/9099/5527/4193 36 Human_cytomegalovirus R-HSA-72312 rRNA processing 148/5218 205/10654 7.71314664605598e-12 4.450864949855254e-11 1.7003528628708393e-11 6158/5393/6138/6227/6206/6234/6191/6128/6132/6129/23404/55226/6176/84135/27043/6224/6146/6154/6202/51096/6169/55272/6175/6218/6173/6167/28987/116832/23481/6156/117246/6143/6139/79159/23160/26168/11340/3921/10607/11103/51388/6208/6170/22984/10813/60528/6203/51504/54433/6147/27292/6222/1454/56902/51602/6134/6155/6231/6142/23521/10171/5822/6207/10969/6233/6188/79707/1453/4691/23016/118460/200916/6122/6230/2091/55651/55127/6194/6166/3028/8780/6136/6125/4839/6232/90459/6160/65083/6193/10200/6210/6229/6205/9790/55131/140801/6235/6181/55759/705/7311/6223/25873/51010/26354/56915/51202/9045/6187/6168/6157/6137/22894/84946/6144/9349/55813/4736/22803/51121/6159/6217/81887/6152/57050/51065/6141/6123/55781/6164/54931/6209/11224/6165/6130/6204/1736/6228/51013/6124/83732/6189/6135/6201/6161/54512/6133/9188 148 Human_cytomegalovirus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 83/5218 102/10654 1.0804893359571998e-11 6.209506061337703e-11 2.3722021511240777e-11 8454/8792/7124/5689/5682/356/9039/143471/5705/10673/5709/5695/7133/5711/5683/5699/5702/8740/944/7187/51330/958/5696/5691/7314/5718/8945/5700/122706/5707/23198/8764/9020/8741/9861/5698/5692/5713/5710/8718/9040/5719/6233/8742/4791/959/4055/8600/330/5706/5714/5688/5687/5708/5704/7311/5971/115650/5694/1147/4050/5684/5720/7186/5690/5717/9491/6500/10197/7316/10213/5715/7132/5701/329/23291/5685/5686/4049/4982/5716/5693/5721 83 Human_cytomegalovirus R-HSA-4615885 SUMOylation of DNA replication proteins 43/5218 45/10654 1.1602474418100183e-11 6.640765845806934e-11 2.536955253594007e-11 23165/9212/348995/6613/57122/23511/6790/23279/23225/9972/6612/8021/55746/7150/51588/3619/7153/332/10762/79902/9883/7155/6396/129401/4928/5903/55706/7175/5111/4927/8086/7329/5905/81929/55143/9631/79023/23636/53371/9688/7341/10401/8480 43 Human_cytomegalovirus R-HSA-388841 Costimulation by the CD28 family 61/5218 70/10654 1.8989430964436334e-11 1.0824744452601764e-10 4.13535019084891e-11 5295/5777/5526/151888/941/3115/3113/3117/2534/2885/2475/5518/3127/5062/5879/5515/1326/5290/5133/8764/5528/9020/6714/5519/29126/10000/1445/916/7525/7409/3932/5781/1493/940/253260/3120/5170/3123/80380/3122/920/64223/8503/4067/5529/998/208/79109/5058/5516/9402/5525/3119/207/919/55615/915/917/942/5527/5296 61 Human_cytomegalovirus R-HSA-73893 DNA Damage Bypass 45/5218 48/10654 2.519077595152529e-11 1.430185989505952e-10 5.463703952134731e-11 56852/5982/9978/25898/57599/6117/10714/55666/7314/51514/6118/9636/11201/51455/5985/5984/6233/5424/8451/124739/54107/7706/8450/5425/5111/6119/83932/5427/1642/5429/9246/51426/7311/7318/5983/56655/57804/7320/7316/5426/9100/10459/7415/7398/5981 45 Human_cytomegalovirus R-HSA-5654727 Negative regulation of FGFR2 signaling 34/5218 34/10654 2.7277654591892604e-11 1.5424472957985858e-10 5.892573027460207e-11 2250/8569/2885/5518/2252/2253/7314/5515/8823/5594/8074/2249/6714/2248/2247/6233/2246/2251/5781/673/2263/7311/5595/5516/8822/10253/8817/2254/7316/26281/10818/867/2255/27006 34 Human_cytomegalovirus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 67/5218 79/10654 2.7913671824379676e-11 1.5692496824364647e-10 5.994965518279258e-11 2074/5982/7507/5431/5435/9978/5433/10980/2965/5439/10987/2067/6117/10714/91603/7314/6118/5438/5985/2068/5984/6233/7874/5424/8451/10450/5434/5436/7515/54107/8450/4331/5425/5111/6119/5427/1161/1642/2071/51426/2873/7311/8533/5983/5432/51138/56655/9318/6917/5440/902/27339/5430/57804/5441/2072/7316/5426/5437/2033/2968/56949/9716/5981/1022/8178/50813 67 Human_cytomegalovirus R-HSA-6782135 Dual incision in TC-NER 58/5218 66/10654 2.7974550446843226e-11 1.5692496824364647e-10 5.994965518279258e-11 2074/5982/7507/5431/5435/9978/5433/2965/5439/2067/6117/10714/91603/7314/6118/5438/5985/2068/5984/6233/7874/5424/8451/10450/5434/5436/54107/8450/4331/5425/5111/6119/5427/1161/1642/2071/51426/7311/5983/5432/56655/6917/5440/902/27339/5430/57804/5441/2072/7316/5426/5437/2033/2968/56949/9716/5981/1022 58 Human_cytomegalovirus R-HSA-69481 G2/M Checkpoints 124/5218 168/10654 3.4066627009345386e-11 1.9034051916332659e-10 7.271531496146822e-11 5689/83990/5682/9156/1763/7531/7486/10971/5982/7533/2810/11200/143471/472/5705/5709/4174/5695/84515/4998/5711/4683/10926/5683/990/84126/5699/5702/8924/55388/672/6117/7334/5001/7465/5696/83695/5691/7314/5718/6118/5700/122706/5707/51588/51720/23198/63967/7534/993/116028/983/9861/9656/5698/5692/5985/5713/4175/5710/7157/5984/5719/6233/7158/5884/5810/4172/80010/5000/8318/51512/7532/4173/5706/9133/580/11073/891/641/5714/6119/3364/10524/5688/5687/144715/5708/1111/5704/7311/5983/5694/4176/7529/1017/5684/5720/5883/10111/8317/5690/5717/9491/545/10197/7336/29086/7316/10213/4171/5715/9088/7341/5701/5685/5686/995/5716/5932/79184/7156/5693/5721 124 Human_cytomegalovirus R-HSA-1433557 Signaling by SCF-KIT 41/5218 43/10654 4.455566997538095e-11 2.46017189511123e-10 9.398533480874993e-11 5295/5777/4893/5578/6776/3717/2534/1215/2885/9846/3845/3265/10603/5879/5290/3815/9306/6714/7525/7409/3932/6777/5781/10019/2241/4318/6774/6772/8651/8503/4067/1111/2886/6654/9402/867/4254/5296/10076/2887/2242 41 Human_cytomegalovirus R-HSA-168325 Viral Messenger RNA Synthesis 41/5218 43/10654 4.455566997538095e-11 2.46017189511123e-10 9.398533480874993e-11 23165/348995/57122/5431/23511/5435/5433/23279/23225/5439/9972/8021/55746/5438/10762/79902/9883/6396/129401/4928/2963/5434/5903/55706/7175/5436/4927/2962/8086/5432/81929/5440/9631/5430/79023/5441/23636/53371/9688/5437/8480 41 Human_cytomegalovirus R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 41/5218 43/10654 4.455566997538095e-11 2.46017189511123e-10 9.398533480874993e-11 2788/361/107/554/2782/2787/22841/5567/10681/112/5573/111/2792/2785/2783/2784/196883/115/2791/5568/359/113/5566/2786/5577/109/54331/5575/59345/51764/94235/114/108/8766/55970/2778/2793/5576/4645/551/2790 41 Human_cytomegalovirus R-HSA-167161 HIV Transcription Initiation 44/5218 47/10654 4.8483469868216186e-11 2.61550672699036e-10 9.991955274312754e-11 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/51616/2959/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 44 Human_cytomegalovirus R-HSA-167162 RNA Polymerase II HIV Promoter Escape 44/5218 47/10654 4.8483469868216186e-11 2.61550672699036e-10 9.991955274312754e-11 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/51616/2959/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 44 Human_cytomegalovirus R-HSA-73776 RNA Polymerase II Promoter Escape 44/5218 47/10654 4.8483469868216186e-11 2.61550672699036e-10 9.991955274312754e-11 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/51616/2959/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 44 Human_cytomegalovirus R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 44/5218 47/10654 4.8483469868216186e-11 2.61550672699036e-10 9.991955274312754e-11 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/51616/2959/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 44 Human_cytomegalovirus R-HSA-75953 RNA Polymerase II Transcription Initiation 44/5218 47/10654 4.8483469868216186e-11 2.61550672699036e-10 9.991955274312754e-11 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/51616/2959/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 44 Human_cytomegalovirus R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 44/5218 47/10654 4.8483469868216186e-11 2.61550672699036e-10 9.991955274312754e-11 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/51616/2959/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 44 Human_cytomegalovirus R-HSA-186797 Signaling by PDGF 52/5218 58/10654 5.4614147986777895e-11 2.934989326923026e-10 1.121246670198614e-10 5295/4893/5335/5291/256076/1280/1289/6696/6776/5327/1290/2885/8440/9564/3845/1285/3265/1399/56034/5290/5340/1284/5921/6778/6714/1292/5154/1293/6777/5781/1291/1286/1287/80310/5782/6774/6772/2889/5159/2886/6654/1282/4690/1299/5045/1281/1398/5155/5296/131873/7057/5156 52 Human_cytomegalovirus R-HSA-163359 Glucagon signaling in metabolic regulation 33/5218 33/10654 5.5875789666439856e-11 2.980042115543459e-10 1.1384580749422157e-10 2788/107/2782/2787/5567/112/5573/111/2785/2783/2784/196883/115/2791/5568/2642/113/5566/2641/2786/5577/109/54331/5575/59345/51764/94235/114/108/55970/2778/5576/2790 33 Human_cytomegalovirus R-HSA-1839126 FGFR2 mutant receptor activation 33/5218 33/10654 5.5875789666439856e-11 2.980042115543459e-10 1.1384580749422157e-10 2250/5431/5435/5433/5439/2252/2253/8823/8074/5438/2249/2248/2247/2246/2251/2963/5434/5436/2263/2962/5432/22916/8822/5440/5430/8817/5441/2254/4686/26281/5437/2255/27006 33 Human_cytomegalovirus R-HSA-5688426 Deubiquitination 200/5218 297/10654 6.999548213579109e-11 3.719005239516749e-10 1.4207623186251936e-10 5689/221937/5682/79594/7419/10474/7321/4738/7375/9817/10445/91833/6478/3091/143471/5705/11274/55031/8239/5709/5695/4792/11047/4609/4194/4089/5711/7347/4088/114803/5683/324/408/64135/5699/8724/8312/5702/8900/8975/57599/377630/672/6881/51616/7187/7040/7345/3054/1540/80351/5696/5691/7314/5718/3607/6314/90865/2648/5700/122706/5707/8027/8737/83444/8767/171023/55611/51720/57646/23198/63967/9101/8517/86/993/890/7417/983/4092/2099/1643/9861/23586/81847/64426/8850/7128/29844/7046/6502/5698/9146/5692/5713/5710/10454/8473/7157/10869/9958/8313/5719/6233/55593/84282/10318/23770/8607/7874/5886/10600/23326/93624/8237/4303/409/330/5706/4287/27005/7706/580/7416/79155/25862/9738/8658/84132/5714/79589/55288/27430/5688/9097/5687/8078/5708/4087/63891/7189/5704/7048/7311/367/114548/387/60/29761/5694/7528/9960/23358/23032/5684/8295/5720/10617/7186/56957/6885/991/51377/10392/5690/2625/57506/5717/9491/4086/1080/57695/10197/64750/29086/7316/10213/8314/8678/9100/7415/5715/3416/5701/329/9099/5685/5686/2033/5728/5716/79184/78990/5887/9736/5693/154/10254/5721/4193 200 Human_cytomegalovirus R-HSA-74751 Insulin receptor signalling cascade 49/5218 54/10654 7.084899238818385e-11 3.7502023038557463e-10 1.4326804554951308e-10 5295/3643/4893/2250/5291/9965/2264/3630/2885/8660/9846/2252/2253/3845/3265/54106/5290/3667/8823/5594/8074/2260/2249/2248/2247/2246/2251/5781/30849/5170/6464/2322/2263/208/9365/6654/2549/5595/8822/8817/2254/5289/26281/10818/2261/2255/27006/5296/2887 49 Human_cytomegalovirus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 65/5218 77/10654 8.490412818399418e-11 4.4773412915005166e-10 1.710467553795428e-10 1912/23165/7486/6045/80012/10274/348995/6613/57122/23511/54780/1911/6672/23279/23225/57332/5371/8924/672/9972/6612/8021/6117/55746/51564/51588/10762/79902/9656/9883/84733/9063/6396/129401/7703/6015/8554/4928/5903/55706/7175/1029/8535/5885/641/4927/8243/142/1069/8086/7329/648/81929/5893/9631/79023/23636/10735/53371/6996/9688/7341/9126/8480/7508 65 Human_cytomegalovirus R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 46/5218 50/10654 8.549563983011129e-11 4.491711226895399e-10 1.7159572644613855e-10 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/2209/5706/5714/5688/5687/5708/9902/5704/5694/5684/5720/5690/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 46 Human_cytomegalovirus R-HSA-4608870 Asymmetric localization of PCP proteins 56/5218 64/10654 9.119829532190442e-11 4.773501851793361e-10 1.8236090357852928e-10 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/1856/8322/23198/9861/5698/5692/5713/5710/5719/6233/7474/7855/144165/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/50855/10197/64750/7316/10213/5715/5701/5685/5686/5716/5693/5721 56 Human_cytomegalovirus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 71/5218 86/10654 9.353240523024698e-11 4.877541724599547e-10 1.8633551295382537e-10 5295/5335/71/51517/5291/4651/2268/10094/2534/8976/2885/5879/25/1072/5290/10093/10006/5336/4771/5594/4644/8398/4641/6714/10810/7525/7410/5580/7409/3710/10109/2214/5747/2209/10451/6850/10152/5337/10092/4650/4067/998/695/3326/10097/60/5058/63916/5595/3984/23646/4690/4627/10458/3708/919/3055/10552/10768/4620/917/3320/1398/10096/7454/9844/5296/5581/5338/10095/2212 71 Human_cytomegalovirus R-HSA-5685938 HDR through Single Strand Annealing (SSA) 36/5218 37/10654 1.2627898082228787e-10 6.560915313571266e-10 2.5064501534351956e-10 83990/9156/1763/7486/5982/472/4683/84126/2067/672/6117/83695/6118/25/5888/116028/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/5983/5893/5883/10111/545/2072/5932/7156 36 Human_cytomegalovirus R-HSA-109606 Intrinsic Pathway for Apoptosis 48/5218 53/10654 1.3209575035837068e-10 6.812850421413404e-10 2.6026962958599355e-10 7531/10971/7533/2810/1869/8655/836/90427/840/7159/637/578/23368/7027/5594/841/7534/4836/598/10000/708/3002/7157/7029/331/57099/317/140735/1029/572/7532/6774/5366/56616/8626/208/7161/7529/5595/27113/596/10018/842/207/54205/5534/581/5599 48 Human_cytomegalovirus R-HSA-2428924 IGF1R signaling cascade 48/5218 53/10654 1.3209575035837068e-10 6.812850421413404e-10 2.6026962958599355e-10 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/54106/5290/3667/8823/8074/2260/2249/2248/2247/8471/2246/2251/5781/30849/5170/6464/2322/2263/3481/208/9365/6654/2549/3480/8822/8817/2254/5289/26281/10818/2261/2255/27006/3479/5296 48 Human_cytomegalovirus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 39/5218 41/10654 1.7031264486574802e-10 8.720007417126299e-10 3.3312827378525263e-10 23165/348995/57122/23511/81608/23279/23225/9972/8021/55746/53981/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10898/10482/51692/8086/22916/81929/9631/29894/79023/23636/4686/8189/53371/9688/10189/8480/55339 39 Human_cytomegalovirus R-HSA-5654743 Signaling by FGFR4 39/5218 41/10654 1.7031264486574802e-10 8.720007417126299e-10 3.3312827378525263e-10 5295/4893/5335/8569/9965/2264/2885/5518/2253/3845/3265/7314/5515/5290/8823/5594/8074/2249/6714/2247/6233/2246/2251/5781/6464/673/6654/7311/2549/5595/5516/8822/10253/8817/2254/7316/26281/10818/867 39 Human_cytomegalovirus R-HSA-9006936 Signaling by TGF-beta family members 81/5218 102/10654 2.0178656593738106e-10 1.0294039305791033e-9 3.9326062240275264e-10 10272/892/7321/25805/4738/9372/91851/130399/8239/9612/4609/4089/22938/23327/4088/650/5499/1030/9110/7040/904/7314/5054/7027/11167/6497/51592/50848/7323/6667/4092/11171/7046/94/5494/2280/9958/9040/6233/7514/1025/7029/8928/57530/4091/5500/4090/4221/4093/5590/9765/269/3726/5501/1024/23645/8812/1874/142/4087/7048/7311/387/57154/51377/10273/5045/50855/4086/23370/64750/659/7316/1875/9611/5933/867/3065/657/56288/25937 81 Human_cytomegalovirus R-HSA-182971 EGFR downregulation 31/5218 31/10654 2.343842322492298e-10 1.1913826678950021e-9 4.5514095641024674e-10 374/7039/6456/30011/2885/8874/10252/7314/1839/8027/2060/2069/9146/6455/6233/29924/255324/5782/5796/998/7311/1956/10253/685/58513/7316/1950/867/5774/10254/6457 31 Human_cytomegalovirus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 61/5218 72/10654 2.4031791425222327e-10 1.2171497239824833e-9 4.649846807379254e-10 8773/55763/5563/71/7531/51807/10971/347688/7533/2810/53632/10381/60412/5898/7846/51552/23433/5879/51422/4644/7534/6810/5872/4641/10376/11336/6844/9882/79058/801/4218/57148/805/84617/7532/10382/7277/5571/208/5867/4012/10383/60/84790/5564/5565/7280/7529/55770/23265/6517/10890/10640/4627/207/8766/149371/9847/808/54536/6814 61 Human_cytomegalovirus R-HSA-2428928 IRS-related events triggered by IGF1R 47/5218 52/10654 2.458115394273563e-10 1.2405112814111743e-9 4.739094383979591e-10 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/54106/5290/3667/8823/8074/2260/2249/2248/2247/8471/2246/2251/5781/30849/5170/2322/2263/3481/208/9365/6654/2549/3480/8822/8817/2254/5289/26281/10818/2261/2255/27006/3479/5296 47 Human_cytomegalovirus R-HSA-674695 RNA Polymerase II Pre-transcription Events 69/5218 84/10654 2.6984201070647395e-10 1.3569198252668405e-9 5.183807047782263e-10 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/51616/11198/904/51497/4300/80349/2959/5438/83860/2068/1025/23168/55677/6883/7936/6829/2957/123169/85403/2963/5434/5436/9646/6878/79577/4331/8148/2962/54457/8812/2071/27125/6880/6908/6882/2961/5432/22916/55840/6877/6917/5440/902/6830/5430/6749/5441/4686/6872/9150/6879/54623/2958/5437/2968/138474/1022/8178 69 Human_cytomegalovirus R-HSA-2408522 Selenoamino acid metabolism 91/5218 118/10654 2.8299982624084547e-10 1.4180204816623147e-9 5.417228365202174e-10 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/1491/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/7296/6203/6147/4143/6222/4837/2936/6134/6155/6231/6142/23521/6207/6233/51091/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/7965/6124/6189/6135/6201/6161/6133 91 Human_cytomegalovirus R-HSA-5654741 Signaling by FGFR3 38/5218 40/10654 3.323610623064383e-10 1.659448140877536e-9 6.33954844488951e-10 5295/4893/2250/5335/8569/2885/5518/2253/3845/3265/7314/5515/5290/8823/5594/8074/2249/6714/2247/6233/2246/5781/6464/673/6654/7311/2549/5595/5516/8822/10253/8817/2254/7316/26281/10818/2261/867 38 Human_cytomegalovirus R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 49/5218 55/10654 3.3969914789316257e-10 1.690093287044427e-9 6.456621334327919e-10 51807/347688/10381/1780/3305/8655/84516/832/7846/3306/3312/51164/3303/3337/10376/3301/10540/140735/84617/5241/11258/1783/10382/93661/10294/55860/830/7277/10671/1639/2908/51143/3326/367/10383/84790/3304/7280/10728/829/1778/4306/1781/2289/10121/3320/10963/55466/2288 49 Human_cytomegalovirus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 56/5218 65/10654 3.44036274219098e-10 1.7056446271144012e-9 6.516031731873948e-10 2074/5982/5431/5435/9978/5433/2965/5439/6117/10714/91603/7314/6118/5438/5985/2068/5984/6233/7874/5424/8451/10450/5434/5436/7515/54107/8450/4331/5425/5111/6119/5427/1161/1642/2071/51426/7311/5983/5432/56655/6917/5440/902/27339/5430/57804/5441/7316/5426/5437/2033/2968/56949/9716/5981/1022 56 Human_cytomegalovirus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 30/5218 30/10654 4.799726452227853e-10 2.3712332788550236e-9 9.058763498018221e-10 56852/5982/9978/57599/6117/10714/7314/51514/6118/5985/5984/6233/5424/8451/54107/8450/5425/5111/6119/5427/1642/7311/5983/56655/57804/7320/7316/5426/7398/5981 30 Human_cytomegalovirus R-HSA-4570464 SUMOylation of RNA binding proteins 43/5218 47/10654 5.736470733692223e-10 2.775584464961735e-9 1.0603496273889407e-9 1912/23165/6045/80012/348995/6613/57122/23511/3190/1911/23279/23225/57332/9972/8021/55746/51602/10762/79902/9883/84733/6396/129401/7703/6015/4928/5903/55706/7175/8535/4927/8086/7329/648/81929/9631/79023/23636/3183/53371/9688/7341/8480 43 Human_cytomegalovirus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 43/5218 47/10654 5.736470733692223e-10 2.775584464961735e-9 1.0603496273889407e-9 4893/71/817/5908/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/816/7450/60/7529/5595/815/5604/5906/808/5245 43 Human_cytomegalovirus R-HSA-6802949 Signaling by RAS mutants 43/5218 47/10654 5.736470733692223e-10 2.775584464961735e-9 1.0603496273889407e-9 4893/71/817/5908/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/816/7450/60/7529/5595/815/5604/5906/808/5245 43 Human_cytomegalovirus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 43/5218 47/10654 5.736470733692223e-10 2.775584464961735e-9 1.0603496273889407e-9 4893/71/817/5908/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/816/7450/60/7529/5595/815/5604/5906/808/5245 43 Human_cytomegalovirus R-HSA-73762 RNA Polymerase I Transcription Initiation 43/5218 47/10654 5.736470733692223e-10 2.775584464961735e-9 1.0603496273889407e-9 2074/9112/5435/5928/2965/64425/1107/2648/30834/8850/57459/2068/3066/9533/5434/9015/79101/9219/5931/221830/7270/4331/9013/1108/54815/2071/10849/57504/6908/53615/5440/902/9014/25885/5441/51082/7343/5437/3065/2968/84172/1022/10919 43 Human_cytomegalovirus R-HSA-9649948 Signaling downstream of RAS mutants 43/5218 47/10654 5.736470733692223e-10 2.775584464961735e-9 1.0603496273889407e-9 4893/71/817/5908/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/816/7450/60/7529/5595/815/5604/5906/808/5245 43 Human_cytomegalovirus R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 48/5218 54/10654 6.220698141198655e-10 2.999569514660173e-9 1.1459180786418576e-9 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/54106/5290/3667/8823/8074/2260/2249/2248/2247/8471/2246/2251/5781/30849/5170/6464/2322/2263/3481/208/9365/6654/2549/3480/8822/8817/2254/5289/26281/10818/2261/2255/27006/3479/5296 48 Human_cytomegalovirus R-HSA-186763 Downstream signal transduction 29/5218 29/10654 9.82792321351338e-10 4.706706083206407e-9 1.7980912145024478e-9 5295/4893/5335/5291/6776/2885/8440/9564/3845/3265/1399/5290/5921/6778/6714/5154/6777/5781/6774/6772/2889/5159/2886/6654/4690/1398/5155/5296/5156 29 Human_cytomegalovirus R-HSA-5654732 Negative regulation of FGFR3 signaling 29/5218 29/10654 9.82792321351338e-10 4.706706083206407e-9 1.7980912145024478e-9 2250/8569/2885/5518/2253/7314/5515/8823/5594/8074/2249/6714/2247/6233/2246/5781/673/7311/5595/5516/8822/10253/8817/2254/7316/26281/10818/2261/867 29 Human_cytomegalovirus R-HSA-191859 snRNP Assembly 47/5218 53/10654 1.1365852204677523e-9 5.40645942708985e-9 2.065416243453135e-9 23165/6633/6606/8487/348995/57122/23511/23279/23225/79084/9972/8021/55746/96764/10762/79902/9883/6636/10419/6396/129401/50628/4928/6635/5903/6632/55706/7175/6637/4927/51808/8086/79833/22916/81929/11218/9631/79023/23636/10073/4686/53371/9688/1207/6634/8480/6628 47 Human_cytomegalovirus R-HSA-194441 Metabolism of non-coding RNA 47/5218 53/10654 1.1365852204677523e-9 5.40645942708985e-9 2.065416243453135e-9 23165/6633/6606/8487/348995/57122/23511/23279/23225/79084/9972/8021/55746/96764/10762/79902/9883/6636/10419/6396/129401/50628/4928/6635/5903/6632/55706/7175/6637/4927/51808/8086/79833/22916/81929/11218/9631/79023/23636/10073/4686/53371/9688/1207/6634/8480/6628 47 Human_cytomegalovirus R-HSA-2132295 MHC class II antigen presentation 93/5218 123/10654 1.166431609697512e-9 5.529749853380797e-9 2.1125165782577663e-9 162/51807/10484/1174/347688/1785/10381/1780/3115/1509/8655/84516/3109/832/3113/10112/7846/3117/9632/6456/11004/3112/163/1759/3127/81930/51164/161/10053/22872/3111/3796/10437/56992/10376/10540/3835/147700/51128/1213/1211/9493/6396/1175/7879/140735/8907/1508/1514/3902/3831/3120/1173/84617/11258/6712/1783/10382/10802/93661/821/55860/830/3123/3832/7277/160/10671/3122/1639/26052/1062/51143/9871/10383/24137/84790/84643/8905/7280/829/1778/164/3119/10120/130340/1781/5641/10121/1520/3799/375/10427 93 Human_cytomegalovirus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 39/5218 42/10654 1.2512461822272681e-9 5.91192827038924e-9 2.258519248032971e-9 23165/348995/57122/23511/81608/23279/23225/9972/8021/55746/53981/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10898/10482/51692/8086/22916/81929/9631/29894/79023/23636/4686/8189/53371/9688/10189/8480/55339 39 Human_cytomegalovirus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 36/5218 38/10654 1.2606464856763952e-9 5.936422246930985e-9 2.2678766209492626e-9 23165/348995/57122/23511/23279/23225/7428/5371/9972/8021/55746/51588/10762/79902/9883/9063/6396/129401/8554/4928/5903/55706/7175/4927/8086/7329/81929/9631/79023/23636/53371/9688/7341/5987/8480/4193 36 Human_cytomegalovirus R-HSA-448424 Interleukin-17 signaling 60/5218 72/10654 1.3129147046414515e-9 6.161946347117212e-9 2.3540330318308134e-9 8454/3605/3725/9252/4790/1848/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/23118/8517/5528/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/79155/7867/5602/3656/7189/7311/23765/6416/5595/5516/1147/1845/6885/5604/10392/6500/7316/4205/23291/5609/1385/5599 60 Human_cytomegalovirus R-HSA-8939211 ESR-mediated signaling 153/5218 223/10654 1.6321499952071956e-9 7.634774728411068e-9 2.916693993883116e-9 5295/2788/374/3725/4893/857/7764/7031/2770/7039/27327/10274/5431/5435/5433/1509/5469/1105/4609/1387/8312/2782/5439/192669/10499/1386/4343/3845/904/7392/3265/8877/2773/2787/6387/1839/5290/4316/5594/2069/10681/5481/5438/4313/865/1655/6667/2792/6714/2099/2494/8850/10000/2785/595/2783/2784/2771/7514/1025/2353/255324/26523/801/2791/2957/805/5170/2963/3838/5434/5590/6464/7090/5241/5747/5436/1903/3315/4318/5885/7033/2962/8503/10524/8243/4602/2786/208/3326/23030/6908/1956/5536/3169/858/23189/5432/3480/10728/5595/7528/3727/27161/596/5440/685/54331/4435/2309/9687/59345/8204/5430/207/5451/2625/57690/1027/51764/94235/5441/10735/192670/2100/1950/55970/4314/346562/2289/7391/2958/5437/2793/3320/2033/4846/9126/9166/3065/2066/861/23028/23112/10498/1385/5296/808/3276/8202/8648/2288/2790 153 Human_cytomegalovirus R-HSA-351202 Metabolism of polyamines 51/5218 59/10654 1.6818091908745155e-9 7.841017684607012e-9 2.995484477298283e-9 5689/5682/143471/5705/5709/5695/5711/4946/5683/5699/5702/5696/5691/5718/1728/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6303/5706/4947/5714/5688/5687/5708/4953/5704/5694/5684/5720/5690/51686/5717/9491/10197/10213/5715/6611/5701/5685/5686/5716/5693/5721 51 Human_cytomegalovirus R-HSA-2559585 Oncogene Induced Senescence 32/5218 33/10654 1.9886652529682773e-9 9.180461233374868e-9 3.5071887636472466e-9 2077/27327/5925/2114/1869/4194/1031/192669/1030/4343/7314/7027/5594/6667/7157/6233/7029/26523/1019/1029/1870/7311/3397/2113/5595/57690/192670/7316/1871/1021/23112/4193 32 Human_cytomegalovirus R-HSA-5654726 Negative regulation of FGFR1 signaling 32/5218 33/10654 1.9886652529682773e-9 9.180461233374868e-9 3.5071887636472466e-9 2250/8569/2885/5518/2253/7314/5515/5594/8074/2260/2249/6714/2248/2247/6233/2246/2251/5781/673/9365/7311/5595/5516/8822/10253/2254/7316/26281/10818/867/2255/27006 32 Human_cytomegalovirus R-HSA-9022692 Regulation of MECP2 expression and activity 32/5218 33/10654 1.9886652529682773e-9 9.180461233374868e-9 3.5071887636472466e-9 2290/79718/817/9212/27327/28996/9612/6907/192669/4204/4343/818/3066/26523/801/805/3930/5566/816/25942/27161/815/8841/57690/192670/9611/2874/3064/3065/23112/1385/808 32 Human_cytomegalovirus R-HSA-350054 Notch-HLH transcription pathway 28/5218 28/10654 2.012167862558638e-9 9.228444138379682e-9 3.5255195534629316e-9 79718/9759/9612/22938/1387/6907/4853/9794/79885/2648/9734/55869/51564/55534/84441/10013/83933/4854/8850/3066/10046/10014/4855/4851/8841/9611/3065/3516 28 Human_cytomegalovirus R-HSA-69205 G1/S-Specific Transcription 28/5218 28/10654 2.012167862558638e-9 9.228444138379682e-9 3.5255195534629316e-9 5422/1869/4998/5928/990/8900/6241/7027/898/5934/1876/983/7298/7029/1719/26271/8318/286826/5111/91750/1874/81620/55957/1875/5933/3065/7083/132660 28 Human_cytomegalovirus R-HSA-111885 Opioid Signalling 72/5218 91/10654 2.7943396433353764e-9 1.2774124083818862e-8 4.8800668412316385e-9 2788/2770/817/5578/5582/2775/5530/107/4988/2782/5499/5518/2773/5515/2787/818/5567/5594/10681/5142/112/5573/5528/111/5443/2792/5519/2785/2783/2784/5613/2771/5580/3710/196883/115/801/2791/805/3838/2781/5568/113/5566/816/2786/5577/1020/109/5516/815/5321/54331/5575/59345/5532/51764/94235/114/3708/108/5173/55970/10768/346562/2793/5576/5534/1385/808/5137/2790 72 Human_cytomegalovirus R-HSA-112399 IRS-mediated signalling 43/5218 48/10654 2.8865652189589722e-009 1.3110592994497525e-8 5.0086072220306785e-9 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/54106/5290/3667/8823/8074/2260/2249/2248/2247/2246/2251/5781/30849/5170/2322/2263/208/9365/6654/2549/8822/8817/2254/5289/26281/10818/2261/2255/27006/5296 43 Human_cytomegalovirus R-HSA-418597 G alpha (z) signalling events 43/5218 48/10654 2.8865652189589722e-009 1.3110592994497525e-8 5.0086072220306785e-9 2788/5579/2770/5578/5582/107/2782/6004/2773/2787/10681/112/111/2792/5588/2785/2783/2784/2771/5580/196883/115/5999/2791/2781/150/113/2786/109/151/54331/59345/51764/94235/114/108/55970/2778/346562/152/2793/5581/2790 43 Human_cytomegalovirus R-HSA-195258 RHO GTPase Effectors 212/5218 327/10654 3.2505294450567668e-9 1.4716223339678224e-8 5.622002187930303e-9 55839/11130/71/6249/51517/5579/9735/7531/5526/51807/10971/5578/9212/347688/388/7533/2810/147841/348995/10381/57122/6280/1780/23122/3688/5048/57405/8655/10094/23279/1432/2017/2491/7846/79784/1060/4628/11004/8976/1855/2885/23433/9184/8826/10499/5518/23332/25909/10726/81930/5062/55746/5879/5515/25/79682/1072/10403/4638/25936/4659/10093/1856/10006/4771/389/5594/3619/64105/7534/94274/332/5528/6714/79902/3796/5519/81565/999/10810/5880/91687/10376/83540/5580/1857/128239/9055/7514/147700/54820/29984/1729/6396/1535/5600/801/64946/9793/30849/10109/5586/140735/5500/4221/805/3831/220134/5170/84617/4928/4688/5590/114793/5903/55055/5747/80776/1783/401541/2316/7532/10382/10627/79172/7277/79980/6232/5501/10152/6279/54821/10092/9183/1062/699/22919/3895/5529/51143/998/695/354/10097/57120/367/10383/5347/387/60/84790/84643/5058/7280/4629/7529/5595/1778/5516/5905/81929/3984/54908/55143/1495/1499/5525/4690/1058/991/79019/4627/348235/80152/10458/1063/8379/1027/1080/23421/55920/79023/6242/1781/10398/4085/5289/5585/5216/10552/81624/55166/4637/51466/995/79003/391/23028/5527/10096/7454/701/23380/9928/29941/3799/103910/57551/5300/808/10095/1536 212 Human_cytomegalovirus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 31/5218 32/10654 3.952495244365506e-9 1.761111805084377e-8 6.727931611828027e-9 25805/4738/9372/4089/23327/4088/5499/9110/7040/7314/4092/11171/7046/2280/9958/9040/6233/7514/5500/5501/23645/4087/7048/7311/57154/51377/10273/5045/64750/7316/867 31 Human_cytomegalovirus R-HSA-381042 PERK regulates gene expression 31/5218 32/10654 3.952495244365506e-9 1.761111805084377e-8 6.727931611828027e-9 5393/1965/23404/3576/3309/4801/6347/11340/468/3484/8894/9451/8570/23016/118460/1968/5073/1051/4800/22926/51010/56915/167227/22894/440/9709/4802/1649/51013/467/54512 31 Human_cytomegalovirus R-HSA-392518 Signal amplification 31/5218 32/10654 3.952495244365506e-9 1.761111805084377e-8 6.727931611828027e-9 2788/64805/2770/2769/5028/1432/2782/2776/2773/2787/10681/2792/6714/2785/2783/2784/2771/2791/6915/2786/5321/54331/59345/51764/94235/55970/2767/346562/2793/9630/2790 31 Human_cytomegalovirus R-HSA-5656169 Termination of translesion DNA synthesis 31/5218 32/10654 3.952495244365506e-9 1.761111805084377e-8 6.727931611828027e-9 5982/6117/10714/7314/6118/9636/11201/51455/5985/5984/6233/5424/124739/54107/7706/5425/5111/6119/5427/5429/9246/51426/7311/7318/5983/56655/57804/7316/5426/9100/5981 31 Human_cytomegalovirus R-HSA-5673000 RAF activation 31/5218 32/10654 3.952495244365506e-9 1.761111805084377e-8 6.727931611828027e-9 4893/5526/817/5605/3717/4296/5894/5518/4140/3845/3265/5515/818/8844/5528/6714/5519/369/801/805/673/5529/816/7529/5516/815/5604/5525/5527/808/5245 31 Human_cytomegalovirus R-HSA-1538133 G0 and Early G1 27/5218 27/10654 4.119304156311061e-9 1.82964676721955e-8 6.989754022496936e-9 9134/1869/4609/5928/990/8900/7027/7153/898/5934/993/890/983/7029/1859/286826/5111/91750/1874/55957/1017/4605/4149/1875/5933/3065/132660 27 Human_cytomegalovirus R-HSA-165159 mTOR signalling 37/5218 40/10654 4.537425226443874e-9 2.0090234964883568e-8 7.675022478360874e-9 5563/53632/6198/29904/10325/2475/10670/92335/64121/84335/51422/7249/1981/5494/1977/1978/57521/28956/6194/389541/58528/64223/5571/6794/6009/208/1975/55004/5562/5564/5565/7248/7529/207/153129/8649/10542 37 Human_cytomegalovirus R-HSA-5689880 Ub-specific processing proteases 150/5218 220/10654 4.640423939402132e-9 2.048187118080941e-8 7.824638287525128e-9 5689/5682/79594/7419/10474/7375/9817/91833/6478/3091/143471/5705/11274/55031/8239/5709/5695/4792/11047/4609/4194/4089/5711/4088/5683/408/64135/5699/8724/8312/5702/8900/8975/57599/377630/6881/51616/1540/80351/5696/5691/7314/5718/6314/90865/2648/5700/122706/5707/8737/55611/57646/23198/63967/9101/8517/993/890/7417/4092/1643/9861/23586/81847/64426/7046/6502/5698/9146/5692/5713/5710/10454/7157/10869/9958/8313/5719/6233/23770/8607/7874/10600/23326/93624/8237/4303/409/330/5706/27005/7416/25862/9738/8658/84132/5714/79589/55288/27430/5688/9097/5687/8078/5708/4087/63891/7189/5704/7311/367/29761/5694/9960/23358/23032/5684/8295/5720/7186/6885/991/5690/2625/5717/9491/4086/1080/57695/10197/64750/7316/10213/8678/9100/5715/3416/5701/329/9099/5685/5686/5728/5716/9736/5693/154/10254/5721/4193 150 Human_cytomegalovirus R-HSA-177243 Interactions of Rev with host cellular proteins 34/5218 36/10654 4.754016922869275e-9 2.0917674460624813e-8 7.991127130217764e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/5902/7514/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/1104/5905/3837/81929/9631/79023/23636/53371/9688/8480 34 Human_cytomegalovirus R-HSA-8878171 Transcriptional regulation by RUNX1 161/5218 239/10654 4.907182924090646e-9 2.1524341299438096e-8 8.222890553239287e-9 1912/9070/5689/1437/5579/5682/1459/6045/9021/5929/27327/80012/1460/143471/5705/5709/5695/28996/1457/1911/6603/10413/5711/1387/3558/5683/10138/57332/5699/8312/5702/192669/83737/5371/57492/6688/4343/4778/5696/5691/7314/55170/5718/84661/25/4773/196528/5700/122706/5707/23198/86/100506658/865/7082/23309/51412/6714/2099/9861/8850/84733/5588/6604/8289/5698/5692/5713/6602/595/5710/3458/896/5719/23067/6233/161882/26523/5781/1493/23429/55193/6015/1514/55904/6595/3562/6597/6929/8535/3674/6938/3958/5706/6599/4331/2623/5714/5688/5687/5708/6886/4602/5704/7311/7161/860/58508/25942/648/5694/6601/23466/4297/4004/27161/894/5684/5720/902/11091/640/8085/5690/2625/57690/5717/9491/4005/6598/10197/192670/5196/7316/10213/5079/10398/122809/5715/5701/5685/5686/2033/1021/84333/6605/50943/3065/861/23112/9757/5716/2811/9739/3276/3977/3559/7057/1022/5693/5721 161 Human_cytomegalovirus R-HSA-6783783 Interleukin-10 signaling 42/5218 47/10654 5.313431225276162e-9 2.323388560617651e-8 8.875983511330888e-9 729230/7124/1437/3593/5743/941/3383/3576/2920/1435/7133/3606/6347/3588/3569/3592/3587/3976/3627/7076/7850/7297/3557/6351/6774/1440/3552/3716/1234/3586/3554/3553/1230/2919/2357/6352/6348/6364/7132/942/6363/5724 42 Human_cytomegalovirus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 67/5218 84/10654 5.377137856985603e-9 2.3439659760482132e-8 8.954594899526295e-9 10445/5982/6613/7507/9978/10980/2965/10987/2067/6612/6117/7334/10714/7314/6118/83444/9557/86/1643/29844/5985/2068/5984/6233/8607/5424/5886/8451/8554/7515/54107/8450/4331/5425/5111/6119/5427/1642/142/2071/1069/7329/51426/2873/7311/60/8533/5983/10038/51138/7528/56655/9318/902/57804/7336/2072/7316/5426/7341/10401/2968/5887/5981/1022/50813/7508 67 Human_cytomegalovirus R-HSA-5654736 Signaling by FGFR1 44/5218 50/10654 6.8332020799721125e-9 2.9694902866051647e-8 1.1344269859862736e-8 5295/4893/2250/5335/8569/2885/5518/2253/3845/3265/7314/5515/5290/5594/8074/2260/2249/6714/2248/2247/6233/2246/2251/200734/5781/6464/673/9365/6654/7311/2549/5595/5516/8822/10253/8817/2254/7316/26281/10818/867/2255/27006/161742 44 Human_cytomegalovirus R-HSA-5654733 Negative regulation of FGFR4 signaling 30/5218 31/10654 7.847625034429475e-9 3.3998326303005234e-8 1.2988296008399877e-8 8569/9965/2264/2885/5518/2253/7314/5515/8823/5594/8074/2249/6714/2247/6233/2246/2251/5781/673/7311/5595/5516/8822/10253/8817/2254/7316/26281/10818/867 30 Human_cytomegalovirus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 36/5218 39/10654 8.61551381839228e-9 3.7210562749375244e-8 1.4215458705839378e-8 5982/25898/6117/10714/55666/7314/6118/9636/11201/51455/5985/5984/6233/5424/124739/54107/7706/5425/5111/6119/83932/5427/5429/9246/51426/7311/7318/5983/56655/57804/7316/5426/9100/10459/7415/5981 36 Human_cytomegalovirus R-HSA-199977 ER to Golgi Anterograde Transport 110/5218 154/10654 1.021559989055496e-8 4.398643622599811e-8 1.680402879148104e-8 6811/23256/374/6711/11014/126003/10960/2153/51807/10484/7039/347688/5861/10381/1780/90411/8655/84516/832/3998/55738/7846/9382/375056/9632/3630/6709/79090/54732/51164/58485/1294/4253/2801/10466/22872/1315/81562/8615/55014/11316/91949/8729/10376/1314/10540/83696/51128/27095/6399/7109/378/6396/26286/1453/26958/140735/84364/22820/84617/11258/6712/2890/1783/10382/10802/93661/55860/2157/830/7277/10671/966/11196/1639/10282/8775/81876/51143/51693/5537/9871/10383/84790/10945/7280/829/1778/9919/51399/25839/55291/122553/63908/1781/10121/2804/57511/22870/5265/8774/381/4905/9276/287/375/64689/10427/22818/372 110 Human_cytomegalovirus R-HSA-380108 Chemokine receptors bind chemokines 50/5218 59/10654 1.0259523939102415e-8 4.40408832507811e-8 1.68248290528926e-8 729230/7852/1237/3576/6360/2920/2921/1236/6370/58191/1524/643/2833/6347/6387/10663/3579/6375/6846/2826/6376/6354/3627/6346/2829/1233/6366/6373/6357/10803/6351/3577/10563/10850/5473/4283/6356/56477/1234/57007/6374/1230/2919/5196/6352/6348/6364/6372/6363/1232 50 Human_cytomegalovirus R-HSA-983169 Class I MHC mediated antigen processing & presentation 235/5218 371/10654 1.0293827154119578e-8 4.405382563221995e-8 1.6829773398672547e-8 8454/8773/5689/11065/9666/5682/8916/3107/7321/51665/65264/9021/10484/8697/26235/9817/9039/6478/811/143471/5705/57674/10333/9690/8452/5709/9978/5695/23304/567/4734/7337/3693/84676/7704/3106/3093/5711/23327/51465/10616/5683/929/3309/25898/5699/9632/7428/5702/22954/83737/51529/10075/29945/8924/56658/51434/10425/25793/23295/3133/54461/29882/7334/4591/3551/7332/5696/5691/9820/55658/7314/996/9354/5718/197131/8945/10952/51320/5700/122706/5707/23198/10533/140462/6892/8517/6810/7323/10517/22872/4008/7096/11059/27252/51444/51433/9861/10134/6502/5698/27246/5692/5713/79654/5710/9040/7324/5719/64682/8925/51191/6233/3685/6047/51128/868/6396/127247/1535/5930/26268/23608/55585/51132/1514/3135/23352/4688/246184/142686/10802/10193/6890/821/2209/5706/79876/26263/8881/29927/7317/80196/84078/5714/26272/8651/64219/140458/5688/5687/26270/63893/118424/5708/55008/2923/10422/695/63891/9246/10393/9902/5704/4012/7327/51343/7311/9871/7318/57520/5694/8673/3105/997/7325/140691/23643/57154/1147/5684/6737/8065/5720/84708/7319/26046/991/10273/7320/5690/223082/5717/9491/6500/26259/10197/7099/7336/4615/64750/23376/6891/7316/10213/25831/7322/5715/9867/5701/9341/23291/5685/5686/55294/135892/8453/80176/8139/948/1520/5716/7064/23194/3134/80204/27338/7097/23014/1536/90678/5693/5721/51676/10427 235 Human_cytomegalovirus R-HSA-114452 Activation of BH3-only proteins 29/5218 30/10654 1.5564562929079434e-8 6.58105243367683e-8 2.514143087327198e-8 7531/10971/7533/2810/1869/8655/90427/7159/637/23368/7027/7534/10000/7157/7029/140735/572/7532/5366/8626/208/7161/7529/27113/596/10018/207/5534/5599 29 Human_cytomegalovirus R-HSA-2424491 DAP12 signaling 29/5218 30/10654 1.5564562929079434e-8 6.58105243367683e-8 2.514143087327198e-8 5295/4893/5335/7305/5291/3824/54209/567/2534/3822/2885/3133/3845/3265/5879/5290/5336/7410/3932/6464/3937/10451/6850/22914/695/6654/9402/27040/5296 29 Human_cytomegalovirus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 29/5218 30/10654 1.5564562929079434e-8 6.58105243367683e-8 2.514143087327198e-8 7124/7375/10616/1540/3551/7314/257397/81858/8737/55072/23118/8517/7128/10454/6233/331/8717/330/27005/7311/1147/7186/56957/6885/7316/7132/329/9099/7185 29 Human_cytomegalovirus R-HSA-5654696 Downstream signaling of activated FGFR2 29/5218 30/10654 1.5564562929079434e-8 6.58105243367683e-8 2.514143087327198e-8 5295/4893/2250/5335/2885/2252/2253/3845/3265/5290/8823/8074/2249/2248/2247/2246/2251/5781/6464/2263/6654/2549/8822/8817/2254/26281/10818/2255/27006 29 Human_cytomegalovirus R-HSA-5655302 Signaling by FGFR1 in disease 35/5218 38/10654 1.632514033173307e-8 6.861432115546316e-8 2.6212558395964175e-8 5295/4893/11052/2250/5335/9530/613/6776/11064/2885/9846/2253/3845/3265/7750/8805/5290/8074/2260/2249/399687/2247/2246/2251/6777/1523/6774/6772/6654/11160/2549/8822/2254/26281/10818 35 Human_cytomegalovirus R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 35/5218 38/10654 1.632514033173307e-8 6.861432115546316e-8 2.6212558395964175e-8 1912/1459/6045/80012/1460/28996/1457/1911/6603/10138/57332/57492/196528/86/865/51412/84733/6604/8289/6602/23429/55193/6015/6595/6597/8535/6599/648/6601/23466/6598/2033/84333/6605/861 35 Human_cytomegalovirus R-HSA-1643713 Signaling by EGFR in Cancer 25/5218 25/10654 1.7258967322422587e-8 7.126283281516423e-8 2.7224362715721382e-8 5295/374/4893/5335/7039/2885/3845/3265/7314/1839/5290/2069/6233/255324/6464/6654/7311/1956/2549/11140/685/7316/1950/867/3320 25 Human_cytomegalovirus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 25/5218 25/10654 1.7258967322422587e-8 7.126283281516423e-8 2.7224362715721382e-8 11065/7321/8697/51529/29945/51434/9184/29882/7314/996/51433/119504/7324/64682/6233/246184/8881/10393/7311/25906/991/7316/4085/4751/701 25 Human_cytomegalovirus R-HSA-392451 G beta:gamma signalling through PI3Kgamma 25/5218 25/10654 1.7258967322422587e-8 7.126283281516423e-8 2.7224362715721382e-8 2788/2782/2787/10681/2792/146850/10000/5294/2785/2783/2784/2791/5170/2786/208/387/54331/59345/207/51764/94235/55970/2793/23533/2790 25 Human_cytomegalovirus R-HSA-418592 ADP signalling through P2Y purinoceptor 1 25/5218 25/10654 1.7258967322422587e-8 7.126283281516423e-8 2.7224362715721382e-8 2788/2769/5028/1432/2782/2776/2787/10681/2792/6714/2785/2783/2784/2791/2786/5321/54331/59345/51764/94235/55970/2767/2793/9630/2790 25 Human_cytomegalovirus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 25/5218 25/10654 1.7258967322422587e-8 7.126283281516423e-8 2.7224362715721382e-8 2308/2475/84335/7249/2932/10000/2931/253260/5170/572/4303/6199/64223/208/79109/1147/2309/842/207/1027/1026/55615/3164/1385/4193 25 Human_cytomegalovirus R-HSA-9006335 Signaling by Erythropoietin 25/5218 25/10654 1.7258967322422587e-8 7.126283281516423e-8 2.7224362715721382e-8 5295/4893/5335/5291/6776/3717/2885/2056/8660/3845/3265/1399/5290/5336/5294/2057/7409/6777/6464/2889/4067/6654/5293/2549/23533 25 Human_cytomegalovirus R-HSA-159227 Transport of the SLBP independent Mature mRNA 32/5218 34/10654 1.7813481346436608e-8 7.291099341797309e-8 2.7854005410125787e-8 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10482/8086/22916/81929/9631/79023/23636/4686/53371/9688/10189/8480 32 Human_cytomegalovirus R-HSA-165054 Rev-mediated nuclear export of HIV RNA 32/5218 34/10654 1.7813481346436608e-8 7.291099341797309e-8 2.7854005410125787e-8 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/5902/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/1104/5905/81929/9631/79023/23636/53371/9688/8480 32 Human_cytomegalovirus R-HSA-4085377 SUMOylation of SUMOylation proteins 32/5218 34/10654 1.7813481346436608e-8 7.291099341797309e-8 2.7854005410125787e-8 23165/348995/6613/57122/23511/23279/23225/9972/8021/55746/51588/10762/79902/9883/6396/129401/4928/5903/55706/7175/10210/4927/8086/7329/81929/9631/79023/23636/53371/9688/7341/8480 32 Human_cytomegalovirus R-HSA-400253 Circadian Clock 57/5218 70/10654 1.8508510362070242e-8 7.553618141969537e-8 2.8856899450855513e-8 8454/79718/5936/28999/3091/5469/1387/150094/6907/2155/5499/10499/23054/1386/9575/23411/85441/96764/7314/5054/8945/10135/1454/64784/4208/6604/6233/8864/1453/5500/5187/10743/1407/406/4209/5501/8553/2908/1390/7311/23373/8841/8204/4862/6500/200186/1408/6720/7316/9611/2033/6256/10498/1385/8648/551/10891 57 Human_cytomegalovirus R-HSA-202733 Cell surface interactions at the vascular wall 99/5218 137/10654 2.108601341588255e-8 8.580666731087465e-8 3.278050762250071e-8 5295/3675/5777/4893/857/5335/6385/960/5291/5175/482/3688/51744/2534/3690/2885/4072/5676/6382/5673/7040/3845/4282/3265/3655/3635/5290/5680/6401/4312/50848/3683/6714/965/8797/4973/914/2335/2734/5671/5478/7525/3685/3932/634/9672/5781/5672/2147/6464/483/3684/7010/1048/2888/3678/1277/338/5670/8140/6403/4067/140885/5624/2886/6402/6654/23657/285/3897/8795/5669/3676/2817/5197/8793/5675/2993/6383/5196/2621/83953/682/1088/57126/5678/6520/440533/5296/3687/1278/481/3689/961/2207/5627/6566/284/9046 99 Human_cytomegalovirus R-HSA-382556 ABC-family proteins mediated transport 78/5218 103/10654 2.2676329773108858e-8 9.201231216293162e-8 3.515123468545011e-8 5689/1965/5682/20/8714/23/143471/91319/5705/5709/5695/64240/5711/5683/5699/6400/5702/51009/4363/5696/5691/7314/5718/5700/122706/5707/10956/79139/91445/64241/23198/9861/11194/8894/5698/5692/5713/5710/5719/10613/6233/27248/10058/1968/5243/6048/5706/335/5714/5688/5687/10347/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/5824/1244/7316/10213/7415/5715/5701/5825/5685/5686/5716/21/5693/5721 78 Human_cytomegalovirus R-HSA-5696400 Dual Incision in GG-NER 37/5218 41/10654 2.4447595834581148e-8 9.891441073301798e-8 3.7788026229494765e-8 5982/7507/9978/2965/2067/6117/10714/7314/6118/9557/1643/5985/2068/5984/6233/5424/8451/54107/8450/5425/5111/6119/5427/1642/142/2071/51426/7311/5983/10038/56655/57804/2072/7316/5426/2968/5981 37 Human_cytomegalovirus R-HSA-74752 Signaling by Insulin receptor 62/5218 78/10654 2.5776876703442367e-8 1.039938177605927e-7 3.972849945848002e-8 5295/3643/4893/2250/5291/535/50617/10312/9965/2264/3630/2885/8660/9846/2252/2253/3845/3265/54106/51606/5290/3667/8823/526/537/9550/5594/8074/2260/2249/2248/2247/529/2246/2251/523/5781/30849/5170/6464/2322/527/2263/208/9365/6654/2549/5595/8822/8817/2254/5289/26281/10818/23545/2261/2255/27006/5296/51382/9296/2887 62 Human_cytomegalovirus R-HSA-8863795 Downregulation of ERBB2 signaling 28/5218 29/10654 3.0834683016362856e-8 1.2381892187138703e-7 4.73022346563089e-8 26469/2064/145957/4145/9542/7314/1839/2065/2069/9101/10000/6233/5782/10193/3084/208/10718/7311/1956/11140/8065/685/10273/207/7316/1950/3320/2066 28 Human_cytomegalovirus R-HSA-176187 Activation of ATR in response to replication stress 34/5218 37/10654 3.086679089265401e-8 1.2381892187138703e-7 4.73022346563089e-8 5982/4174/84515/4998/10926/990/84126/55388/6117/5001/6118/63967/993/5985/4175/5984/5884/5810/4172/5000/8318/4173/6119/3364/144715/1111/5983/4176/1017/5883/8317/545/4171/995 34 Human_cytomegalovirus R-HSA-5628897 TP53 Regulates Metabolic Genes 67/5218 86/10654 3.131283011597232e-8 1.2525132046388928e-7 4.784945032674e-8 5563/7531/10971/9997/27327/7295/7533/2810/53632/7001/10325/192669/2475/10670/4513/4343/64121/7296/9377/2936/51422/7249/27244/7534/1351/2821/10000/2877/54541/7157/50484/26523/57521/28956/83667/389541/7532/58528/64223/5571/10128/25824/6009/8626/208/55004/5562/4697/5564/5565/7248/7529/27161/27165/207/57690/192670/153129/2539/54205/143686/8649/5728/23112/10542/1327/5052 67 Human_cytomegalovirus R-HSA-109704 PI3K Cascade 39/5218 44/10654 3.2643868446839806e-8 1.3020557159532705e-7 4.974211056011672e-8 5295/2250/5291/9965/2264/2885/8660/9846/2252/2253/54106/5290/3667/8823/8074/2260/2249/2248/2247/2246/2251/5781/30849/5170/2322/2263/208/9365/2549/8822/8817/2254/5289/26281/10818/2261/2255/27006/5296 39 Human_cytomegalovirus R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 31/5218 33/10654 3.439186011102265e-8 1.3640489869385885e-7 5.21104240674057e-8 23165/348995/57122/23511/23279/23225/9972/8021/55746/3303/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/3304/81929/9631/79023/23636/53371/9688/8480 31 Human_cytomegalovirus R-HSA-180746 Nuclear import of Rev protein 31/5218 33/10654 3.439186011102265e-8 1.3640489869385885e-7 5.21104240674057e-8 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/1104/3837/81929/9631/79023/23636/53371/9688/8480 31 Human_cytomegalovirus R-HSA-3371571 HSF1-dependent transactivation 24/5218 24/10654 3.5322068278273437e-8 1.3930944575856863e-7 5.322004095591252e-8 817/3305/1387/2475/3306/3312/818/3303/84335/3337/3297/57521/1410/64223/26353/3281/816/3326/3304/10728/815/3320/2033/2288 24 Human_cytomegalovirus R-HSA-982772 Growth hormone receptor signaling 24/5218 24/10654 3.5322068278273437e-8 1.3930944575856863e-7 5.322004095591252e-8 5777/5770/9021/6776/3717/5618/6868/8660/1154/3667/2690/5594/5617/8835/6777/6774/6772/8651/1442/4067/2689/5595/25970/2688 24 Human_cytomegalovirus R-HSA-168276 NS1 Mediated Effects on Host Pathways 36/5218 40/10654 4.53183111459279e-8 1.7823514551247622e-7 6.809072918426685e-8 3839/23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/4927/10898/3840/8086/3837/81929/9631/79023/23636/53371/9688/8480 36 Human_cytomegalovirus R-HSA-6802957 Oncogenic MAPK signaling 57/5218 71/10654 4.9078786665832586e-8 1.924872747228197e-7 7.353543464665137e-8 4893/71/817/5908/8546/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/4763/818/8805/8844/7094/5594/7414/10533/23164/57085/6714/2335/1445/2266/2243/369/801/57670/805/283455/3674/409/673/816/56829/7450/60/9444/7529/5595/4000/27044/815/22906/5604/10018/10142/5906/808/5245 57 Human_cytomegalovirus R-HSA-8986944 Transcriptional Regulation by MECP2 51/5218 62/10654 5.5255293077735024e-8 2.1564160658368171e-7 8.238102643859251e-8 627/2290/79718/5770/817/9212/27327/6657/28996/9612/4988/6907/192669/4204/3654/4343/6750/28514/818/6446/54487/4208/3066/26523/801/2891/805/2904/3930/4233/6515/5566/1392/816/25942/27161/815/8841/5468/4986/57690/192670/9611/2874/2289/3064/5728/3065/23112/1385/808 51 Human_cytomegalovirus R-HSA-3000171 Non-integrin membrane-ECM interactions 49/5218 59/10654 5.528879259709453e-8 2.1564160658368171e-7 8.238102643859251e-8 6385/5578/1280/1289/7448/3688/3693/3910/1290/3690/87/6382/7040/1285/3655/3918/375790/1284/284217/1756/2247/2335/1288/3685/5154/9672/3691/1302/1286/1287/8573/7276/1277/3912/3913/51399/3371/1282/6383/3915/1301/1281/3673/3914/780/5155/7057/1278/4921 49 Human_cytomegalovirus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 33/5218 36/10654 5.822854614392484e-8 2.2648009107913306e-7 8.652162570382553e-8 4893/71/5908/5605/5037/2244/3690/408/5894/8826/4140/3845/3265/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/283455/3674/409/673/7450/60/7529/5595/5604/5906 33 Human_cytomegalovirus R-HSA-2871796 FCERI mediated MAPK activation 30/5218 32/10654 6.62745718853893e-8 2.5635878355667067e-7 9.793610825168863e-8 3725/4893/5335/2885/3845/3265/5062/5879/5601/5336/5594/4214/7410/7409/2353/6464/3937/10451/6850/4067/5602/6654/5058/6416/5595/9402/27040/5609/5599/2207 30 Human_cytomegalovirus R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 30/5218 32/10654 6.62745718853893e-8 2.5635878355667067e-7 9.793610825168863e-8 2788/2149/2769/408/2782/2776/2787/5594/10681/2792/6714/2785/2783/2784/2151/2791/2147/409/2786/5595/54331/59345/51764/94235/55970/2767/2793/9630/9002/2790 30 Human_cytomegalovirus R-HSA-166208 mTORC1-mediated signalling 23/5218 23/10654 7.228275416098631e-8 2.765601028768172e-7 1.056535680099085e-7 6198/29904/10325/2475/10670/64121/84335/1981/1977/1978/57521/28956/6194/389541/58528/64223/6009/1975/55004/7529/153129/8649/10542 23 Human_cytomegalovirus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 23/5218 23/10654 7.228275416098631e-8 2.765601028768172e-7 1.056535680099085e-7 11065/7321/8697/51529/29945/51434/29882/7314/996/983/51433/119504/7324/64682/6233/246184/8881/891/10393/7311/25906/991/7316 23 Human_cytomegalovirus R-HSA-5654695 PI-3K cascade:FGFR2 23/5218 23/10654 7.228275416098631e-8 2.765601028768172e-7 1.056535680099085e-7 5295/2250/2885/2252/2253/5290/8823/8074/2249/2248/2247/2246/2251/5781/2263/2549/8822/8817/2254/26281/10818/2255/27006 23 Human_cytomegalovirus R-HSA-5654699 SHC-mediated cascade:FGFR2 23/5218 23/10654 7.228275416098631e-8 2.765601028768172e-7 1.056535680099085e-7 4893/2250/2885/2252/2253/3845/3265/8823/8074/2249/2248/2247/2246/2251/6464/2263/6654/8822/8817/2254/26281/2255/27006 23 Human_cytomegalovirus R-HSA-167172 Transcription of the HIV genome 58/5218 73/10654 7.524089238655849e-8 2.870980392419359e-7 1.0967934962068575e-7 6884/6875/6874/5431/5435/5433/2960/8732/2965/5439/6873/6881/51616/11198/904/51497/2959/5438/83860/2068/1025/6883/7936/6829/2957/2963/5434/5436/6878/4331/8148/2962/54457/8812/2071/6880/6908/6882/2961/5432/22916/6877/6917/5440/902/5430/6749/5441/4686/6872/9150/6879/2958/5437/2968/138474/1022/8178 58 Human_cytomegalovirus R-HSA-6802952 Signaling by BRAF and RAF fusions 54/5218 67/10654 8.648839336257962e-8 3.291233996067895e-7 1.2573419348016555e-7 4893/71/817/5908/8546/5605/5037/3717/2244/3690/408/5894/8826/4140/3845/3265/818/8805/8844/7094/5594/7414/10533/23164/57085/6714/2335/1445/2266/2243/369/801/57670/805/283455/3674/409/673/816/56829/7450/60/9444/7529/5595/4000/27044/815/22906/5604/10018/10142/5906/808 54 Human_cytomegalovirus R-HSA-2980766 Nuclear Envelope Breakdown 44/5218 52/10654 8.900847844734313e-8 3.378003710346607e-7 1.2904903528611815e-7 23165/5579/91754/5578/348995/57122/23511/23279/23225/4001/9972/8021/55746/10762/983/79902/9883/7444/2010/64900/23175/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/5347/7112/4000/81929/9631/79023/23636/7443/53371/9688/8815/23399/8480 44 Human_cytomegalovirus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 46/5218 55/10654 9.313226203281885e-8 3.521406418255159e-7 1.345274132572059e-7 834/4790/7295/29108/1432/10628/5603/83737/3654/7334/1540/3551/7314/257397/8767/23118/841/8517/5970/7128/837/598/10454/6233/5600/6300/5608/4791/351/330/3656/7189/3326/4210/7311/114548/1147/596/6885/842/10392/10910/835/58484/7316/329 46 Human_cytomegalovirus R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 50/5218 61/10654 9.36012386516608e-8 3.521406418255159e-7 1.345274132572059e-7 71/51517/4651/10094/8976/2885/5879/25/1072/10093/10006/4771/5594/4644/4641/10810/7410/7409/10109/2214/5747/2209/10451/6850/10152/10092/4650/998/695/3326/10097/60/5058/63916/5595/3984/4690/4627/10458/919/10552/4620/917/3320/1398/10096/7454/9844/10095/2212 50 Human_cytomegalovirus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 48/5218 58/10654 9.453775753554333e-8 3.521406418255159e-7 1.345274132572059e-7 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/388585/28514/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/102/8850/3066/6233/5663/10046/1024/10014/26508/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 48 Human_cytomegalovirus R-HSA-2644603 Signaling by NOTCH1 in Cancer 48/5218 58/10654 9.453775753554333e-8 3.521406418255159e-7 1.345274132572059e-7 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/388585/28514/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/102/8850/3066/6233/5663/10046/1024/10014/26508/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 48 Human_cytomegalovirus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 48/5218 58/10654 9.453775753554333e-8 3.521406418255159e-7 1.345274132572059e-7 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/388585/28514/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/102/8850/3066/6233/5663/10046/1024/10014/26508/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 48 Human_cytomegalovirus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 48/5218 58/10654 9.453775753554333e-8 3.521406418255159e-7 1.345274132572059e-7 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/388585/28514/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/102/8850/3066/6233/5663/10046/1024/10014/26508/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 48 Human_cytomegalovirus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 48/5218 58/10654 9.453775753554333e-8 3.521406418255159e-7 1.345274132572059e-7 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/388585/28514/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/102/8850/3066/6233/5663/10046/1024/10014/26508/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 48 Human_cytomegalovirus R-HSA-168253 Host Interactions with Influenza Factors 37/5218 42/10654 1.0800990463472089e-7 4.002051203307553e-7 1.5288936639430023e-7 3839/23165/348995/57122/23511/23279/23225/3836/9972/8021/7040/55746/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/4927/10898/3840/8086/3837/81929/9631/79023/23636/53371/9688/8480 37 Human_cytomegalovirus R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 37/5218 42/10654 1.0800990463472089e-7 4.002051203307553e-7 1.5288936639430023e-7 2788/6000/1459/2770/1460/2775/10576/1457/2782/10574/10693/2773/2787/10575/10681/2792/2785/2783/2784/2771/2791/2781/5082/2786/22948/10694/54331/59345/51764/94235/7203/908/55970/346562/2793/6950/2790 37 Human_cytomegalovirus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 32/5218 35/10654 1.0958152033466184e-7 4.049626788220574e-7 1.5470688462774473e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10482/8086/22916/81929/9631/79023/23636/4686/53371/9688/10189/8480 32 Human_cytomegalovirus R-HSA-164952 The role of Nef in HIV-1 replication and disease pathogenesis 26/5218 27/10654 1.2056739923144309e-7 4.4093220290356325e-7 1.684482324190497e-7 162/1174/567/2534/163/1794/5062/5879/51606/161/10053/926/3932/1175/8907/940/1173/160/920/8905/164/919/130340/3055/9844/375 26 Human_cytomegalovirus R-HSA-3000170 Syndecan interactions 26/5218 27/10654 1.2056739923144309e-7 4.4093220290356325e-7 1.684482324190497e-7 6385/5578/1289/7448/3688/3693/1290/3690/87/6382/7040/3655/2247/2335/3685/9672/3691/8573/1277/51399/3371/6383/1281/3673/7057/1278 26 Human_cytomegalovirus R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress 26/5218 27/10654 1.2056739923144309e-7 4.4093220290356325e-7 1.684482324190497e-7 5393/23404/3576/4801/6347/11340/468/3484/8570/23016/118460/5073/1051/4800/22926/51010/56915/167227/22894/440/9709/4802/1649/51013/467/54512 26 Human_cytomegalovirus R-HSA-912526 Interleukin receptor SHC signaling 26/5218 27/10654 1.2056739923144309e-7 4.4093220290356325e-7 1.684482324190497e-7 5295/5777/1437/5291/3558/3717/2885/9846/3635/5290/1439/3718/3567/3562/6464/1438/8503/3636/6654/3716/5293/3561/3568/3560/5296/3559 26 Human_cytomegalovirus R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 29/5218 31/10654 1.2746016240150337e-7 4.6373103013260143e-7 1.771580116610043e-7 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/3837/81929/9631/79023/23636/53371/9688/8480 29 Human_cytomegalovirus R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 29/5218 31/10654 1.2746016240150337e-7 4.6373103013260143e-7 1.771580116610043e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/81929/9631/79023/23636/53371/9688/8480 29 Human_cytomegalovirus R-HSA-3899300 SUMOylation of transcription cofactors 39/5218 45/10654 1.2867200411586158e-7 4.669334582348791e-7 1.7838142730115375e-7 1912/6045/80012/6613/28996/9612/1911/9994/1387/57332/115426/10499/6612/11315/3622/51588/1655/84733/10155/9063/7703/6015/8554/8535/4869/10210/10521/1616/7329/25942/648/1487/8204/7341/10401/2033/6294/8648/10891 39 Human_cytomegalovirus R-HSA-1250196 SHC1 events in ERBB2 signaling 22/5218 22/10654 1.479042036642819e-7 5.298959764867911e-7 2.0243484149577622e-7 4893/5578/2064/145957/9542/2885/3845/3265/1839/2065/2069/5580/6464/5782/3084/6654/10718/1956/685/1950/2066/5581 22 Human_cytomegalovirus R-HSA-392170 ADP signalling through P2Y purinoceptor 12 22/5218 22/10654 1.479042036642819e-7 5.298959764867911e-7 2.0243484149577622e-7 2788/64805/2770/2782/2773/2787/10681/2792/2785/2783/2784/2771/2791/2786/54331/59345/51764/94235/55970/346562/2793/2790 22 Human_cytomegalovirus R-HSA-5655332 Signaling by FGFR3 in disease 22/5218 22/10654 1.479042036642819e-7 5.298959764867911e-7 2.0243484149577622e-7 5295/4893/2250/5335/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/6654/2549/8822/8817/2254/26281/10818/2261 22 Human_cytomegalovirus R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 22/5218 22/10654 1.479042036642819e-7 5.298959764867911e-7 2.0243484149577622e-7 5295/4893/2250/5335/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/6654/2549/8822/8817/2254/26281/10818/2261 22 Human_cytomegalovirus R-HSA-912631 Regulation of signaling by CBL 22/5218 22/10654 1.479042036642819e-7 5.298959764867911e-7 2.0243484149577622e-7 5295/5291/2534/2885/1399/7314/5290/6233/7525/7409/6850/8503/2889/4067/29760/7311/5293/7316/3055/867/1398/5296 22 Human_cytomegalovirus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 45/5218 54/10654 1.6034164973858133e-7 5.729975706393973e-7 2.1890083627148028e-7 2074/7507/5431/5435/9978/5433/10980/2965/5439/10987/91603/7314/5438/2068/6233/7874/8451/10450/5434/5436/8450/4331/1161/1642/2071/2873/7311/8533/5432/51138/9318/6917/5440/902/27339/5430/5441/7316/5437/2033/2968/56949/9716/1022/50813 45 Human_cytomegalovirus R-HSA-187687 Signalling to ERKs 31/5218 34/10654 2.0570177401174448e-7 7.313840853750915e-7 2.7940884242424627e-7 4893/5605/5898/1432/5603/2885/3845/3265/1399/5594/9261/6714/4914/5600/6300/6464/673/7867/2889/6654/5900/7529/5595/25759/5604/57498/10818/53358/4803/1398/5906 31 Human_cytomegalovirus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 31/5218 34/10654 2.0570177401174448e-7 7.313840853750915e-7 2.7940884242424627e-7 7321/9140/9474/3093/64135/83737/7187/1540/7314/29110/9636/7323/23586/7128/3661/51191/6233/55593/84282/54476/7706/9246/7311/7318/5094/9641/57506/7316/7322/54941/5300 31 Human_cytomegalovirus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 38/5218 44/10654 2.2933470231717012e-7 8.113147257853657e-7 3.099445461096904e-7 892/7321/8239/9612/4609/4089/22938/23327/4088/1030/904/7314/5054/7027/6497/51592/7323/6667/4092/5494/6233/1025/7029/4221/3726/1024/8812/1874/142/4087/7311/64750/7316/1875/9611/5933/3065/25937 38 Human_cytomegalovirus R-HSA-451927 Interleukin-2 family signaling 38/5218 44/10654 2.2933470231717012e-7 8.113147257853657e-7 3.099445461096904e-7 5295/5777/1437/5291/6776/84868/3558/3717/2885/9846/3600/3635/5290/1439/3718/3567/3932/6777/3562/6464/6775/1438/6774/6850/6772/8503/3636/6654/3716/5293/2185/6655/3561/3578/3568/3560/5296/3559 38 Human_cytomegalovirus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 25/5218 26/10654 2.3792823622045967e-7 8.37507391496018e-7 3.1995086502277605e-7 25805/9372/23327/4088/5499/9110/7040/7314/4092/11171/7046/9958/6233/7514/5500/5501/23645/4087/7048/7311/57154/51377/10273/64750/7316 25 Human_cytomegalovirus R-HSA-912694 Regulation of IFNA signaling 25/5218 26/10654 2.3792823622045967e-7 8.37507391496018e-7 3.1995086502277605e-7 3443/5777/3442/5770/9021/11274/3445/3444/3451/3448/3439/3452/6773/7297/5781/3446/3455/6772/8651/3440/3454/3716/3456/3441/3449 25 Human_cytomegalovirus R-HSA-1980143 Signaling by NOTCH1 57/5218 73/10654 2.9411245529732295e-7 1.0326941073781314e-6 3.9451756045919944e-7 8454/79718/892/182/3091/23385/9978/9759/9612/4609/22938/1387/6907/408/83737/6868/9794/388585/28514/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/7091/8650/102/8850/3066/6233/7089/5663/7090/409/10046/1024/10014/26508/7088/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 57 Human_cytomegalovirus R-HSA-111931 PKA-mediated phosphorylation of CREB 21/5218 21/10654 3.026102362059476e-7 1.0468678441719268e-6 3.9993231786173346e-7 107/5567/112/5573/111/5613/196883/115/801/805/5568/113/5566/5577/109/5575/114/108/5576/1385/808 21 Human_cytomegalovirus R-HSA-389513 CTLA4 inhibitory signaling 21/5218 21/10654 3.026102362059476e-7 1.0468678441719268e-6 3.9993231786173346e-7 5526/941/2534/5518/5515/5528/6714/5519/10000/7525/3932/5781/1493/4067/5529/208/5516/5525/207/942/5527 21 Human_cytomegalovirus R-HSA-5620916 VxPx cargo-targeting to cilium 21/5218 21/10654 3.026102362059476e-7 1.0468678441719268e-6 3.9993231786173346e-7 55763/1260/1258/1262/60412/6010/9727/5310/8729/11336/117177/378/4218/50807/5311/55770/23265/10640/8766/149371/54536 21 Human_cytomegalovirus R-HSA-5654688 SHC-mediated cascade:FGFR1 21/5218 21/10654 3.026102362059476e-7 1.0468678441719268e-6 3.9993231786173346e-7 4893/2250/2885/2253/3845/3265/8074/2260/2249/2248/2247/2246/2251/6464/9365/6654/8822/2254/26281/2255/27006 21 Human_cytomegalovirus R-HSA-5654689 PI-3K cascade:FGFR1 21/5218 21/10654 3.026102362059476e-7 1.0468678441719268e-6 3.9993231786173346e-7 5295/2250/2885/2253/5290/8074/2260/2249/2248/2247/2246/2251/5781/9365/2549/8822/2254/26281/10818/2255/27006 21 Human_cytomegalovirus R-HSA-6807004 Negative regulation of MET activity 21/5218 21/10654 3.026102362059476e-7 1.0468678441719268e-6 3.9993231786173346e-7 5770/3082/6456/30011/2885/7314/8027/2060/9101/9146/6455/6233/4233/5795/5771/7311/26018/7316/867/10254/6457 21 Human_cytomegalovirus R-HSA-5674135 MAP2K and MAPK activation 35/5218 40/10654 3.5304680056622436e-7 1.2183575862677547e-6 4.6544611736155996e-7 4893/71/5908/5605/5037/2244/3690/408/5894/8826/4140/3845/3265/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/28956/283455/3674/409/673/7450/60/7529/5595/5604/8649/5906 35 Human_cytomegalovirus R-HSA-180910 Vpr-mediated nuclear import of PICs 30/5218 33/10654 3.8510168962905586e-7 1.3224955585310016e-6 5.052296878060271e-7 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/3159/79023/23636/53371/9688/8815/8480 30 Human_cytomegalovirus R-HSA-389356 CD28 co-stimulation 30/5218 33/10654 3.8510168962905586e-7 1.3224955585310016e-6 5.052296878060271e-7 5295/941/2534/2885/2475/5062/5879/1326/5290/9020/6714/10000/7525/7409/3932/940/253260/5170/64223/8503/4067/998/208/79109/5058/9402/207/55615/942/5296 30 Human_cytomegalovirus R-HSA-5696395 Formation of Incision Complex in GG-NER 37/5218 43/10654 4.0736801749326967e-7 1.3955575879088166e-6 5.331413931081081e-7 6613/7507/9978/2965/2067/6612/6117/7334/7314/6118/9557/1643/2068/6233/5886/8451/8554/8450/4331/6119/1642/142/2071/1069/7329/7311/10038/902/7336/2072/7316/7341/10401/2968/5887/1022/7508 37 Human_cytomegalovirus R-HSA-933541 TRAF6 mediated IRF7 activation 27/5218 29/10654 4.6840554854967583e-7 1.5906548906889655e-6 6.076739302796512e-7 3443/3442/1387/64135/3445/29110/3444/23586/3451/3448/3661/3439/10010/84282/3452/3446/3665/7706/3440/7189/9641/3456/3441/7186/57506/3449/2033 27 Human_cytomegalovirus R-HSA-5654700 FRS-mediated FGFR2 signaling 24/5218 25/10654 4.688364912186937e-7 1.5906548906889655e-6 6.076739302796512e-7 4893/2250/2885/2252/2253/3845/3265/8823/8074/2249/2248/2247/2246/2251/5781/2263/6654/8822/8817/2254/26281/10818/2255/27006 24 Human_cytomegalovirus R-HSA-5654708 Downstream signaling of activated FGFR3 24/5218 25/10654 4.688364912186937e-7 1.5906548906889655e-6 6.076739302796512e-7 5295/4893/2250/5335/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/5781/6464/6654/2549/8822/8817/2254/26281/10818/2261 24 Human_cytomegalovirus R-HSA-9006115 Signaling by NTRK2 (TRKB) 24/5218 25/10654 4.688364912186937e-7 1.5906548906889655e-6 6.076739302796512e-7 5295/627/4893/5335/2534/2885/3845/3265/5879/5290/1795/6714/4909/5781/4908/6464/2904/7074/6654/2549/1020/4915/10818/8851 24 Human_cytomegalovirus R-HSA-168638 NOD1/2 Signaling Pathway 32/5218 36/10654 5.204053138605567e-7 1.7571479182629828e-6 6.712788473627275e-7 834/1432/5603/83737/3654/7334/1540/3551/7314/257397/8767/23118/841/8517/7128/837/10454/6233/5600/6300/5608/330/3656/7189/7311/1147/6885/842/10392/835/7316/329 32 Human_cytomegalovirus R-HSA-176033 Interactions of Vpr with host cellular proteins 32/5218 36/10654 5.204053138605567e-7 1.7571479182629828e-6 6.712788473627275e-7 23165/348995/57122/23511/292/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/3159/79023/23636/53371/9688/8815/8480/291 32 Human_cytomegalovirus R-HSA-163125 Post-translational modification: synthesis of GPI-anchored proteins 69/5218 93/10654 5.701587364888663e-7 1.9205346913309182e-6 7.336970897653254e-7 116372/146183/146760/10026/419/154064/123904/7512/2813/5277/7007/8875/55350/22854/4062/94005/83639/353091/248/4045/4061/7070/54742/27076/137797/2350/338328/6975/249/8813/8000/23627/5067/80328/135228/349667/1048/2215/53942/1087/420/161357/349633/5329/58530/8434/503542/646627/10942/84628/284348/2822/171169/683/9488/1368/130576/152330/8876/4978/147719/50863/10232/51299/8581/1043/257194/266727/80740 69 Human_cytomegalovirus R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 20/5218 20/10654 6.19076039210089e-7 2.0557996773768995e-6 7.853720358400087e-7 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Human_cytomegalovirus R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 20/5218 20/10654 6.19076039210089e-7 2.0557996773768995e-6 7.853720358400087e-7 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Human_cytomegalovirus R-HSA-3232118 SUMOylation of transcription factors 20/5218 20/10654 6.19076039210089e-7 2.0557996773768995e-6 7.853720358400087e-7 9112/6613/7022/6612/4286/6670/51588/7157/668/7158/9063/8554/7020/1029/7329/7021/3090/7341/10401/4193 20 Human_cytomegalovirus R-HSA-5213460 RIPK1-mediated regulated necrosis 20/5218 20/10654 6.19076039210089e-7 2.0557996773768995e-6 7.853720358400087e-7 356/7314/11035/8737/841/8797/6233/8772/331/8717/8743/330/8837/197259/7311/8795/7186/355/7316/329 20 Human_cytomegalovirus R-HSA-5218859 Regulated Necrosis 20/5218 20/10654 6.19076039210089e-7 2.0557996773768995e-6 7.853720358400087e-7 356/7314/11035/8737/841/8797/6233/8772/331/8717/8743/330/8837/197259/7311/8795/7186/355/7316/329 20 Human_cytomegalovirus R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 20/5218 20/10654 6.19076039210089e-7 2.0557996773768995e-6 7.853720358400087e-7 22938/1387/4088/4853/9794/388585/2648/55534/3280/84441/8850/2324/10046/59/4855/23493/4851/23462/2033/3516 20 Human_cytomegalovirus R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 34/5218 39/10654 6.351386693521856e-7 2.1041770504655938e-6 8.038535233163265e-7 83990/9156/1763/7486/5982/472/4683/84126/672/6117/83695/6118/5888/116028/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/1111/5983/5883/10111/675/545/5932/7156 34 Human_cytomegalovirus R-HSA-9006931 Signaling by Nuclear Receptors 188/5218 299/10654 6.545218818069254e-7 2.1633023699158473e-6 8.26441021999849e-7 5295/2788/374/3725/4893/857/7764/79718/7031/5160/5165/2770/10901/7039/27327/10274/5915/5431/5435/5433/1509/5469/1105/9612/4609/64240/1387/6907/8312/2782/5439/192669/10499/1386/5914/4343/3845/904/1071/7392/3265/8877/2773/10062/2787/6387/1839/5290/4316/344/64241/5594/2069/10681/1737/5481/5438/348/4313/865/1655/6667/2792/6714/2099/2494/8850/10000/5162/2785/595/2783/2784/2771/7514/1025/2353/6257/255324/5164/26523/801/2791/2957/805/5105/5170/2963/3838/5434/5590/6464/112724/7090/5241/6319/5747/5436/1903/3315/4318/341/5885/19/7033/2962/8503/10524/8243/4602/2786/208/3326/23030/6908/1956/5536/3169/51109/858/23189/5432/3480/10728/5595/7528/3727/27161/596/5440/8841/685/54331/4435/2309/9687/59345/8204/5430/207/5451/2625/57690/1027/51764/94235/5441/10735/6720/192670/2100/1950/9611/55970/2874/2194/4314/346562/2289/7391/2958/5163/5437/2793/3320/2033/4846/9126/9166/3065/2066/861/23028/6256/23112/10498/1385/1738/5296/808/6258/3276/5916/8202/8648/2288/2172/2790 188 Human_cytomegalovirus R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 36/5218 42/10654 7.210528019050676e-7 2.3776167332139e-6 9.083150049882646e-7 83990/9156/1763/7486/5982/472/4683/84126/672/6117/83695/6118/5888/116028/7517/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/1111/79728/5983/5883/10111/675/545/5932/7156 36 Human_cytomegalovirus R-HSA-202040 G-protein activation 26/5218 28/10654 8.947877961010637e-7 2.9436009740894806e-6 1.1245365563395074e-6 2788/2770/2775/4988/2782/2773/2787/10681/5443/2792/2785/2783/2784/2771/2791/2781/2786/54331/59345/51764/94235/5173/55970/346562/2793/2790 26 Human_cytomegalovirus R-HSA-5260271 Diseases of Immune System 23/5218 24/10654 9.22378529463385e-7 3.0202534174056886e-6 1.153819898545385e-6 4790/10333/4792/929/51135/7187/3551/8517/5970/7096/4791/81793/7098/695/81622/23643/1147/7099/4615/7100/948/7097/148022 23 Human_cytomegalovirus R-HSA-5602358 Diseases associated with the TLR signaling cascade 23/5218 24/10654 9.22378529463385e-7 3.0202534174056886e-6 1.153819898545385e-6 4790/10333/4792/929/51135/7187/3551/8517/5970/7096/4791/81793/7098/695/81622/23643/1147/7099/4615/7100/948/7097/148022 23 Human_cytomegalovirus R-HSA-114604 GPVI-mediated activation cascade 31/5218 35/10654 9.506337400091312e-7 3.09836181928902e-6 1.1836594569801805e-6 5295/5777/5291/388/2534/5879/5290/5336/146850/5880/5294/7410/7409/3932/5781/5170/5590/3937/10451/1277/6850/8503/4067/998/387/27040/23533/391/5296/1278/2207 31 Human_cytomegalovirus R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 31/5218 35/10654 9.506337400091312e-7 3.09836181928902e-6 1.1836594569801805e-6 23165/91754/348995/57122/23511/23279/23225/9972/8021/55746/10762/983/79902/9883/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/81929/9631/79023/23636/53371/9688/8480 31 Human_cytomegalovirus R-HSA-438064 Post NMDA receptor activation events 61/5218 81/10654 1.083771357305706e-6 3.5241341133635887e-6 1.3463161871477229e-6 5563/4893/51807/817/347688/53632/10381/107/7846/6196/8874/6197/3845/3265/5879/5923/818/5567/5594/51422/5573/6714/10376/6195/5613/801/2891/4747/805/5170/84617/3838/2904/2890/10382/5568/7277/5566/5571/27330/3084/816/5577/5562/10383/84790/5564/5565/7280/5595/815/28964/5575/114/5576/4137/2066/88/1385/808/8536 61 Human_cytomegalovirus R-HSA-111465 Apoptotic cleavage of cellular proteins 33/5218 38/10654 1.1386115885893392e-6 3.693928840400437e-6 1.4111824442618295e-6 2339/660/836/324/9414/4001/6709/840/2934/22985/63967/841/100506658/7082/5339/28988/10134/999/5588/5580/839/1828/5747/118/1829/8428/4000/51765/1499/329/4137/7431/6304 33 Human_cytomegalovirus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 19/5218 19/10654 1.2663730865549729e-6 4.0249510290505684e-006 1.5376420273959633e-6 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Human_cytomegalovirus R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 19/5218 19/10654 1.2663730865549729e-6 4.0249510290505684e-006 1.5376420273959633e-6 1869/4609/5928/990/7027/7153/5934/993/7029/286826/5111/91750/1874/55957/4149/1875/5933/3065/132660 19 Human_cytomegalovirus R-HSA-163615 PKA activation 19/5218 19/10654 1.2663730865549729e-6 4.0249510290505684e-006 1.5376420273959633e-6 107/5567/112/5573/111/196883/115/801/805/5568/113/5566/5577/109/5575/114/108/5576/808 19 Human_cytomegalovirus R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 19/5218 19/10654 1.2663730865549729e-6 4.0249510290505684e-006 1.5376420273959633e-6 11065/7321/8697/51529/29945/51434/29882/996/51433/119504/7324/64682/246184/8881/10393/51343/25906/991/8556 19 Human_cytomegalovirus R-HSA-176412 Phosphorylation of the APC/C 19/5218 19/10654 1.2663730865549729e-6 4.0249510290505684e-006 1.5376420273959633e-6 11065/7321/8697/51529/29945/51434/29882/996/983/51433/119504/7324/64682/246184/8881/891/10393/25906/5347 19 Human_cytomegalovirus R-HSA-392851 Prostacyclin signalling through prostacyclin receptor 19/5218 19/10654 1.2663730865549729e-6 4.0249510290505684e-006 1.5376420273959633e-6 2788/2782/2787/10681/2792/2785/2783/2784/2791/2786/54331/59345/51764/94235/55970/2778/2793/5739/2790 19 Human_cytomegalovirus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 19/5218 19/10654 1.2663730865549729e-6 4.0249510290505684e-006 1.5376420273959633e-6 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Human_cytomegalovirus R-HSA-77595 Processing of Intronless Pre-mRNAs 19/5218 19/10654 1.2663730865549729e-6 4.0249510290505684e-006 1.5376420273959633e-6 51585/81608/1477/53981/11051/8106/1478/23283/10914/10898/51692/22916/1479/79869/29894/4686/8189/10978/55339 19 Human_cytomegalovirus R-HSA-8851708 Signaling by FGFR2 IIIa TM 19/5218 19/10654 1.2663730865549729e-6 4.0249510290505684e-006 1.5376420273959633e-6 5431/5435/5433/5439/5438/2247/2246/2963/5434/5436/2263/2962/5432/22916/5440/5430/5441/4686/5437 19 Human_cytomegalovirus R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 28/5218 31/10654 1.3380742480487545e-6 4.214784208618896e-6 1.6101635246742345e-6 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/2645/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/79023/23636/53371/9688/8480 28 Human_cytomegalovirus R-HSA-1839124 FGFR1 mutant receptor activation 28/5218 31/10654 1.3380742480487545e-6 4.214784208618896e-6 1.6101635246742345e-6 5295/11052/2250/9530/613/6776/11064/2885/9846/2253/7750/8805/5290/8074/2260/2249/399687/2247/2246/2251/6777/1523/6774/6772/11160/8822/2254/26281 28 Human_cytomegalovirus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 28/5218 31/10654 1.3380742480487545e-6 4.214784208618896e-6 1.6101635246742345e-6 3725/9252/1848/1432/6196/5518/1386/6197/51231/5515/5601/1849/5594/5528/9261/5519/5598/4208/6195/2353/5600/5602/5595/5516/1845/4205/1385/5599 28 Human_cytomegalovirus R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 28/5218 31/10654 1.3380742480487545e-6 4.214784208618896e-6 1.6101635246742345e-6 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/2645/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/79023/23636/53371/9688/8480 28 Human_cytomegalovirus R-HSA-5685942 HDR through Homologous Recombination (HRR) 52/5218 67/10654 1.3739445254966376e-6 4.318111365846575e-6 1.6496373414680025e-6 83990/9156/1763/7486/5982/472/4683/84126/672/6117/10714/83695/7314/6118/5888/116028/7517/5985/5984/6233/5884/5810/5424/80010/54107/580/11073/5425/641/5111/6119/3364/10524/5427/144715/5429/1111/79728/51426/7311/5983/56655/5883/10111/57804/675/545/7316/5426/5932/7156/5981 52 Human_cytomegalovirus R-HSA-5654716 Downstream signaling of activated FGFR4 25/5218 27/10654 1.7049386985831593e-6 5.3464447385413985e-6 2.0424889813058124e-6 5295/4893/5335/9965/2264/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/2251/5781/6464/6654/2549/8822/8817/2254/26281/10818 25 Human_cytomegalovirus R-HSA-428930 Thromboxane signalling through TP receptor 22/5218 23/10654 1.8115760927367785e-6 5.655652191958723e-6 2.1606147354148533e-6 2788/2769/2782/2776/2787/10681/2792/2785/2783/2784/2791/6915/2786/54331/59345/51764/94235/55970/2767/2793/9630/2790 22 Human_cytomegalovirus R-HSA-5654693 FRS-mediated FGFR1 signaling 22/5218 23/10654 1.8115760927367785e-6 5.655652191958723e-6 2.1606147354148533e-6 4893/2250/2885/2253/3845/3265/8074/2260/2249/2248/2247/2246/2251/5781/9365/6654/8822/2254/26281/10818/2255/27006 22 Human_cytomegalovirus R-HSA-163685 Integration of energy metabolism 77/5218 108/10654 1.8590859106301614e-6 5.7911348720514765e-6 2.212372846604594e-6 2788/5563/2770/5578/2769/107/2782/3630/2776/8826/5518/31/6513/5515/2787/10411/5567/1131/51422/10681/112/5573/5528/111/2792/5519/51085/2785/2783/2784/2771/9370/7086/6844/2182/3710/196883/115/2791/5568/2642/150/113/6616/5566/2864/32/6794/2641/6514/2786/5577/6888/5565/109/5516/54331/5575/59345/51764/94235/114/3708/108/55970/2778/2194/2767/10768/152/2793/5576/948/47/5906/9630/2790 77 Human_cytomegalovirus R-HSA-445717 Aquaporin-mediated transport 42/5218 52/10654 2.188936153576452e-6 6.803580804052196e-6 2.599155047002596e-6 2788/361/107/554/2782/2787/22841/5567/10681/112/5573/111/2792/362/2785/2783/2784/196883/115/2791/5568/359/113/5566/2786/5577/109/54331/5575/59345/51764/94235/114/108/8766/55970/2778/2793/5576/4645/551/2790 42 Human_cytomegalovirus R-HSA-180786 Extension of Telomeres 27/5218 30/10654 2.482508207351785e-6 7.682135287805083e-6 2.934787030553527e-6 2237/1763/5982/5422/6117/10714/6118/5557/5985/5984/23649/8607/5424/55651/54107/5425/5111/6119/5427/5983/56655/7015/57804/10856/5426/1736/5981 27 Human_cytomegalovirus R-HSA-6804758 Regulation of TP53 Activity through Acetylation 27/5218 30/10654 2.482508207351785e-6 7.682135287805083e-6 2.934787030553527e-6 64769/84289/29117/5928/1107/5371/23774/3622/27154/57459/10000/7994/3066/7157/5608/7862/9219/5931/1108/54815/208/53615/5305/207/2033/3065/5300 27 Human_cytomegalovirus R-HSA-5654221 Phospholipase C-mediated cascade; FGFR2 18/5218 18/10654 2.5902200285766694e-6 7.894003896614611e-6 3.0157266680398228e-6 2250/5335/2252/2253/8823/8074/2249/2248/2247/2246/2251/2263/8822/8817/2254/26281/2255/27006 18 Human_cytomegalovirus R-HSA-5654704 SHC-mediated cascade:FGFR3 18/5218 18/10654 2.5902200285766694e-6 7.894003896614611e-6 3.0157266680398228e-6 4893/2250/2885/2253/3845/3265/8823/8074/2249/2247/2246/6464/6654/8822/8817/2254/26281/2261 18 Human_cytomegalovirus R-HSA-5654710 PI-3K cascade:FGFR3 18/5218 18/10654 2.5902200285766694e-6 7.894003896614611e-6 3.0157266680398228e-6 5295/2250/2885/2253/5290/8823/8074/2249/2247/2246/5781/2549/8822/8817/2254/26281/10818/2261 18 Human_cytomegalovirus R-HSA-5675482 Regulation of necroptotic cell death 18/5218 18/10654 2.5902200285766694e-6 7.894003896614611e-6 3.0157266680398228e-6 356/7314/8737/841/8797/6233/8772/331/8717/8743/330/8837/7311/8795/7186/355/7316/329 18 Human_cytomegalovirus R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 18/5218 18/10654 2.5902200285766694e-6 7.894003896614611e-6 3.0157266680398228e-6 2810/6790/1647/7027/5934/983/7157/7029/891/5111/1874/25946/5933/2033/995/10498/581/3276 18 Human_cytomegalovirus R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 18/5218 18/10654 2.5902200285766694e-6 7.894003896614611e-6 3.0157266680398228e-6 4893/5578/2885/6196/6197/3845/3265/1839/5594/5598/6195/2520/887/6654/1956/5595/4314/1385 18 Human_cytomegalovirus R-HSA-8964315 G beta:gamma signalling through BTK 18/5218 18/10654 2.5902200285766694e-6 7.894003896614611e-6 3.0157266680398228e-6 2788/2782/2787/10681/2792/2785/2783/2784/2791/695/2786/54331/59345/51764/94235/55970/2793/2790 18 Human_cytomegalovirus R-HSA-447115 Interleukin-12 family signaling 45/5218 57/10654 3.0862489215295892e-6 9.38539628836644e-6 3.585479592819416e-6 3593/5908/3313/6175/5898/3717/3181/4001/3594/4282/5062/3572/10148/1072/3592/6627/9049/27250/9987/3185/3458/5478/302/51561/7297/6775/3595/821/4478/6774/6772/998/6648/3716/6888/246778/3586/829/6647/6950/9466/6845/375/5721/5034 45 Human_cytomegalovirus R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic 131/5218 202/10654 3.2159789440080913e-6 9.758832657679724e-6 3.72814255986419e-6 6811/400/4122/11014/60592/11311/8674/51807/347688/5861/10381/1780/5048/8655/84516/832/55738/10112/636/7846/3482/9382/11004/10749/83452/6293/27314/8675/339122/81930/54732/7110/51164/60561/10618/9321/55275/23299/51209/10466/8398/9827/1315/22836/347517/3796/5870/11316/56992/91949/8729/4074/10376/1314/10540/3835/147700/8677/378/9493/26286/26958/140735/1523/3831/84364/22820/51542/84617/11258/1783/27333/55850/10382/93661/55860/830/3832/7277/10671/23303/1639/8775/81876/9183/9712/1062/10244/51143/9648/10383/24137/84790/54734/84643/10945/57589/7280/829/22931/1778/9609/5321/25839/5050/84316/9950/63908/1781/22930/738/25782/10121/9367/10226/9341/9342/6836/57511/547/51560/8774/143187/381/4905/9276/3799/9266/375/22818/372 131 Human_cytomegalovirus R-HSA-6803529 FGFR2 alternative splicing 24/5218 26/10654 3.2397355511975014e-6 9.809779905561467e-6 3.7476058102137484e-6 5431/5435/5433/5439/7072/7073/5438/3185/4670/5725/2963/5434/5436/2962/5432/22916/5440/23543/5430/3178/5441/4686/5437/3187 24 Human_cytomegalovirus R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 41/5218 51/10654 3.6438959063893126e-6 1.1009882910292173e-5 4.206078175208807e-6 51807/347688/10381/1780/5048/8655/84516/832/636/7846/51164/23299/8398/5870/10376/10540/140735/84617/11258/1783/10382/93661/55860/830/7277/10671/1639/51143/10383/84790/7280/829/22931/1778/5321/5050/1781/22930/25782/10121/51560 41 Human_cytomegalovirus R-HSA-1489509 DAG and IP3 signaling 35/5218 42/10654 4.024093665122934e-6 1.2132599315831029e-5 4.634986730255425e-6 5335/817/5578/5582/107/818/5567/112/5573/111/5613/5580/3710/196883/115/801/805/3838/5568/113/5566/816/5577/109/815/5575/114/3708/108/10768/5576/1385/5581/808/5137 35 Human_cytomegalovirus R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK 26/5218 29/10654 4.59010060821305e-6 1.3780088819539392e-5 5.2643730463401835e-6 5563/53632/10325/2475/10670/92335/64121/51422/7249/5494/57521/28956/389541/58528/64223/5571/6794/6009/55004/5562/5564/5565/7248/153129/8649/10542 26 Human_cytomegalovirus R-HSA-5218920 VEGFR2 mediated vascular permeability 26/5218 29/10654 4.59010060821305e-6 1.3780088819539392e-5 5.2643730463401835e-6 857/2475/5062/5879/1500/10000/3728/7410/7409/801/253260/805/5170/10451/64223/1003/208/79109/5058/1495/1499/207/55615/3320/4846/808 26 Human_cytomegalovirus R-HSA-164378 PKA activation in glucagon signalling 17/5218 17/10654 5.297475570846002e-6 1.563699287998149e-5 5.973761484502499e-6 107/5567/112/5573/111/196883/115/5568/113/5566/5577/109/5575/114/108/2778/5576 17 Human_cytomegalovirus R-HSA-180292 GAB1 signalosome 17/5218 17/10654 5.297475570846002e-6 1.563699287998149e-5 5.973761484502499e-6 5295/374/7039/55824/2885/5829/1839/5290/2069/6714/1445/255324/5781/1956/2549/685/1950 17 Human_cytomegalovirus R-HSA-2033519 Activated point mutants of FGFR2 17/5218 17/10654 5.297475570846002e-6 1.563699287998149e-5 5.973761484502499e-6 2250/2252/2253/8823/8074/2249/2248/2247/2246/2251/2263/8822/8817/2254/26281/2255/27006 17 Human_cytomegalovirus R-HSA-432142 Platelet sensitization by LDL 17/5218 17/10654 5.297475570846002e-6 1.563699287998149e-5 5.973761484502499e-6 5777/5526/5175/2268/1432/5518/5515/5528/5519/5781/338/5529/5516/5321/5525/5527/7804 17 Human_cytomegalovirus R-HSA-450385 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA 17/5218 17/10654 5.297475570846002e-6 1.563699287998149e-5 5.973761484502499e-6 5393/23404/11340/9261/23016/118460/677/51010/56915/167227/7529/22894/207/55802/51013/54464/54512 17 Human_cytomegalovirus R-HSA-450513 Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA 17/5218 17/10654 5.297475570846002e-6 1.563699287998149e-5 5.973761484502499e-6 5393/23404/11340/9261/23016/118460/3842/7538/51010/56915/167227/7529/22894/55802/51013/54464/54512 17 Human_cytomegalovirus R-HSA-450604 KSRP (KHSRP) binds and destabilizes mRNA 17/5218 17/10654 5.297475570846002e-6 1.563699287998149e-5 5.973761484502499e-6 5393/23404/1432/11340/7534/5600/8570/23016/118460/5073/51010/56915/167227/22894/207/51013/54512 17 Human_cytomegalovirus R-HSA-8934593 Regulation of RUNX1 Expression and Activity 17/5218 17/10654 5.297475570846002e-6 1.563699287998149e-5 5.973761484502499e-6 27327/192669/5371/4343/865/6714/595/896/26523/5781/27161/894/57690/192670/1021/861/23112 17 Human_cytomegalovirus R-HSA-397795 G-protein beta:gamma signalling 28/5218 32/10654 5.672147889322456e-6 1.667303596694367e-5 6.369558447299804e-6 2788/2782/2787/10681/2792/146850/10000/5294/2785/2783/2784/2791/5170/998/695/2786/208/387/5058/54331/59345/207/51764/94235/55970/2793/23533/2790 28 Human_cytomegalovirus R-HSA-69190 DNA strand elongation 28/5218 32/10654 5.672147889322456e-6 1.667303596694367e-5 6.369558447299804e-6 2237/1763/5982/5422/4174/84515/84296/6117/10714/6118/64785/5557/5985/4175/5984/23649/5424/4172/8318/4173/5425/5111/6119/5983/4176/57804/4171/5981 28 Human_cytomegalovirus R-HSA-390466 Chaperonin-mediated protein folding 68/5218 95/10654 5.904264507711165e-6 1.7319175889286085e-5 6.616401674211415e-6 2788/6000/9134/1459/2770/51807/1460/10381/2775/10576/1457/7846/2782/10574/10564/54461/10693/8877/2773/5201/2787/5204/10575/10681/898/10517/2792/26985/2785/10376/2783/2784/10238/7157/2771/2791/84617/2629/2781/8237/10382/7277/6774/26272/26270/5082/2786/10383/60/84790/22948/7280/10694/8841/54331/22803/59345/51764/94235/7203/908/55970/346562/2793/6950/55294/6499/2790 68 Human_cytomegalovirus R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 23/5218 25/10654 6.138111969277347e-6 1.7856325728806828e-5 6.821607690954165e-6 5982/6117/10714/7314/6118/5985/5984/6233/5424/7515/54107/5425/5111/6119/5427/51426/7311/5983/56655/57804/7316/5426/5981 23 Human_cytomegalovirus R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 23/5218 25/10654 6.138111969277347e-6 1.7856325728806828e-5 6.821607690954165e-6 5520/8900/28227/5518/7465/5515/993/890/983/5519/7514/2305/9133/891/4331/5347/5516/1017/994/902/9088/995/1022 23 Human_cytomegalovirus R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 23/5218 25/10654 6.138111969277347e-6 1.7856325728806828e-5 6.821607690954165e-6 22938/1387/9794/9787/388585/23286/2648/55534/3280/84441/4854/8850/5087/2173/23129/10046/6772/26508/23493/4851/23462/2033/3516 23 Human_cytomegalovirus R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 23/5218 25/10654 6.138111969277347e-6 1.7856325728806828e-5 6.821607690954165e-6 3107/10484/811/567/3106/3309/9632/3133/6892/22872/10134/51128/6396/3135/10802/6890/821/2923/9871/3105/6891/3134/10427 23 Human_cytomegalovirus R-HSA-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle 30/5218 35/10654 6.410404957257505e-6 1.8571708188927096e-5 7.094903472294966e-6 811/6400/51009/7314/9695/5700/10956/79139/91445/80267/6233/55741/23193/267/7841/6048/821/56886/10206/84447/2923/7311/55768/7844/7316/5589/7415/51035/11236/5887 30 Human_cytomegalovirus R-HSA-8953750 Transcriptional Regulation by E2F6 30/5218 35/10654 6.410404957257505e-6 1.8571708188927096e-5 7.094903472294966e-6 80314/6045/80012/79813/1869/1911/5928/10138/23512/672/6241/5888/83746/7027/2146/1876/7029/8726/7703/317/23429/6015/5931/1111/648/23468/8317/4149/5932/10919 30 Human_cytomegalovirus R-HSA-111996 Ca-dependent events 32/5218 38/10654 6.807099210729537e-6 1.968048396038437e-5 7.518486321588228e-6 817/5578/5582/107/818/5567/5594/112/5573/111/5613/5580/196883/115/801/805/3838/5568/113/5566/816/5577/109/815/5321/5575/114/108/5576/1385/808/5137 32 Human_cytomegalovirus R-HSA-8853659 RET signaling 34/5218 41/10654 6.9067146859578106e-6 1.9886818564066663e-5 7.597311816864582e-6 5295/2674/1796/5335/5291/5578/55816/2668/2885/8660/9846/5290/5567/6714/5598/220164/9260/55715/5781/6464/5568/5566/8503/2886/6654/5293/2549/5909/10818/53358/5979/5296/2887/9046 34 Human_cytomegalovirus R-HSA-8875878 MET promotes cell motility 34/5218 41/10654 6.9067146859578106e-6 1.9886818564066663e-5 7.597311816864582e-6 3675/5908/3082/1280/1289/3688/3910/1290/2885/1399/5879/3918/284217/6714/2335/64759/84951/1302/85440/5747/1277/3912/4233/2889/3913/2549/3915/1301/1281/3673/3914/1398/5906/1278 34 Human_cytomegalovirus R-HSA-5218921 VEGFR2 mediated cell proliferation 20/5218 21/10654 6.948392099292933e-6 1.9925328056628205e-5 7.612023502494778e-6 4893/5335/5579/5578/3845/3265/8877/5921/6714/5580/3791/3710/801/805/5170/5590/7422/3708/10768/808 20 Human_cytomegalovirus R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 20/5218 21/10654 6.948392099292933e-6 1.9925328056628205e-5 7.612023502494778e-6 25904/55571/55835/57472/85456/29883/1263/7832/10769/7157/5325/4869/4850/246175/4848/23019/4849/9337/28984/995 20 Human_cytomegalovirus R-HSA-2682334 EPH-Ephrin signaling 66/5218 92/10654 7.139974010263081e-6 2.043309635457402e-5 7.806004962012056e-6 71/2042/1212/23385/10094/2050/79784/2534/4628/8976/163/1759/8440/8874/3265/5062/5879/1072/161/10093/5921/6453/4313/102/6714/1943/7525/1942/7410/1213/1211/1175/10109/5663/1173/2904/5747/7074/10627/1945/10451/4318/160/8218/10092/4067/6386/998/10097/387/60/5058/4629/3984/28964/4627/6383/10398/10552/4637/1946/10096/103910/1944/10095/1969 66 Human_cytomegalovirus R-HSA-5689603 UCH proteinases 72/5218 102/10654 7.156815283471241e-6 2.043974831466026e-5 7.80854619377347e-6 5689/221937/5682/4738/10445/143471/5705/5709/5695/11047/5711/7347/5683/5699/5702/7040/7345/3054/5696/5691/7314/5718/3607/5700/122706/5707/83444/171023/23198/86/4092/9861/29844/7046/5698/5692/5713/5710/8473/9958/5719/6233/8607/5706/580/5714/5688/5687/5708/5704/7048/7311/60/5694/7528/5684/5720/51377/5690/5717/9491/10197/7316/10213/8314/5715/5701/5685/5686/5716/5693/5721 72 Human_cytomegalovirus R-HSA-1236394 Signaling by ERBB4 45/5218 58/10654 7.236536709412381e-6 2.062559450779885e-5 7.879544552545765e-6 5295/4893/2670/51741/23385/6776/4734/10413/145957/83737/6868/9542/2885/3845/3265/7314/6387/1839/5290/6678/2065/2069/23118/348/11059/6714/2099/2567/3925/6233/5663/6464/5241/3084/6654/10718/7311/1956/685/7316/1950/9611/2066/6285/11033 45 Human_cytomegalovirus R-HSA-5619115 Disorders of transmembrane transporters 115/5218 176/10654 7.465537881312275e-6 2.1235307751288252e-5 8.11247178596613e-6 23165/5689/5682/285195/348995/143471/91319/57122/5705/23511/5709/5695/554/6523/23279/64240/5711/10999/23225/5683/5699/6400/5702/51009/9972/8021/55746/5696/5691/6513/7314/5718/5700/122706/5707/10956/79139/91445/64241/23198/10762/553/9861/79902/9883/5698/5692/6521/5713/5710/5719/10613/6233/27248/2645/6396/129401/552/10058/4928/5903/55706/7175/6048/5706/19/335/5714/4927/5688/5687/5708/8086/6514/5704/7311/11160/5694/9197/81929/5684/5720/9631/5690/5717/9491/1080/79023/23636/10197/1244/7316/10213/53371/3098/9688/7415/6519/5715/5701/5685/682/5686/5826/6520/5716/21/213/5693/551/5721/6566/8480/1356/10599 115 Human_cytomegalovirus R-HSA-948021 Transport to the Golgi and subsequent modification 120/5218 185/10654 8.10989011875119e-6 2.3021623562906604e-5 8.794893571056576e-6 6811/23256/374/4122/6711/11014/126003/10960/2153/51807/10484/7039/347688/5861/10381/1780/90411/8655/84516/832/3998/55738/7846/9382/375056/9632/3630/6709/79090/54732/51164/58485/1294/4253/2801/4249/10466/2517/22872/1315/81562/8615/55014/11316/91949/8729/10376/1314/10540/83696/51128/27095/6399/7109/378/6396/26286/1453/26958/140735/84364/22820/84617/11258/6712/2890/1783/8703/10382/10802/93661/55860/2157/830/7277/10671/966/11196/1639/8702/10282/8775/81876/51143/51693/5537/9871/10383/84790/10945/8704/7280/829/1778/9919/51399/25839/55291/122553/63908/1781/6484/10121/2525/2804/57511/22870/5265/8774/381/4905/11320/2683/9276/287/375/64689/10427/22818/372 120 Human_cytomegalovirus R-HSA-75067 Processing of Capped Intronless Pre-mRNA 25/5218 28/10654 8.456196219267273e-6 2.3956386874704868e-5 9.151998873335966e-6 51585/81608/1477/53981/134353/11051/8106/1478/23283/6636/10914/6635/6637/10898/51692/22916/1479/79869/29894/4686/8189/10978/6634/55339/6628 25 Human_cytomegalovirus R-HSA-381119 Unfolded Protein Response (UPR) 67/5218 94/10654 8.734526554630417e-6 2.4695207608272343e-5 9.434248719966484e-6 5393/10525/1965/2673/23404/5526/811/3576/55738/100137049/10130/3309/4801/55062/6347/11340/9820/10488/8720/9695/7094/58477/468/3484/22872/51726/3068/8894/7466/9451/2931/64061/8570/23016/118460/1968/1200/6464/5073/7184/7494/118/1051/84447/5611/4800/1639/10954/4189/22926/51010/56915/167227/22894/4000/440/9709/4802/116138/1649/2081/30827/51013/467/51360/54512/7709 67 Human_cytomegalovirus R-HSA-72766 Translation 179/5218 291/10654 8.876245344133687e-6 2.5045598085250967e-5 9.568107522101707e-6 6158/6138/5464/6227/6206/1965/6234/27335/6191/6128/6132/1917/84545/6129/1915/80222/6176/8668/6224/6146/6154/8662/26986/6202/6150/6169/6175/6218/6728/6173/6167/116832/28977/6156/6143/1973/124995/28973/51116/6139/51067/64975/3921/8665/10667/65005/6208/6170/6203/51504/10952/29093/6147/8666/6222/64432/8667/6727/7818/6184/79731/58477/2935/6134/6747/6731/55699/6155/6729/6231/6142/7458/8663/23521/23107/8894/1981/6185/6207/64978/1977/6233/28957/51386/6188/1978/64965/7284/200916/123263/6122/1968/6230/8669/6194/2107/6166/1938/1650/1983/6136/6125/1937/10056/6232/6160/6748/29927/1933/6193/6210/6229/6205/54148/140801/23438/79587/6235/6181/8893/1975/7311/6223/25873/8664/6730/23708/9045/6187/6168/6157/6137/1974/55037/6144/9349/4736/8891/29088/51121/6159/56945/6217/1936/6152/79590/51065/6141/10480/6123/1967/6164/63931/8661/64963/9669/6209/1964/11224/6165/6130/8890/6204/64969/6228/7965/78988/6124/2193/3646/6189/9789/6135/6201/6161/51649/54998/8892/6133 179 Human_cytomegalovirus R-HSA-5654687 Downstream signaling of activated FGFR1 27/5218 31/10654 1.0207437432647209e-5 2.874414381033454e-5 1.098105374333205e-5 5295/4893/2250/5335/2885/2253/3845/3265/5290/8074/2260/2249/2248/2247/2246/2251/5781/6464/9365/6654/2549/8822/2254/26281/10818/2255/27006 27 Human_cytomegalovirus R-HSA-6807878 COPI-mediated anterograde transport 71/5218 101/10654 1.044395281276451e-5 2.9351468184376112e-5 1.1213068362900862e-5 6811/6711/11014/51807/347688/5861/10381/1780/8655/84516/832/55738/7846/9382/3630/6709/54732/51164/2801/10466/1315/8615/11316/91949/8729/10376/1314/10540/378/26286/26958/140735/84364/22820/84617/11258/6712/1783/10382/93661/55860/830/7277/10671/966/1639/10282/8775/81876/51143/10383/84790/10945/7280/829/1778/25839/63908/1781/10121/2804/57511/8774/381/4905/9276/287/375/64689/22818/372 71 Human_cytomegalovirus R-HSA-1295596 Spry regulation of FGF signaling 16/5218 16/10654 1.0833245890553573e-5 2.9791426199022326e-5 1.1381144428603776e-5 8569/2885/5518/7314/5515/5594/6714/6233/5781/673/7311/5595/5516/10253/7316/867 16 Human_cytomegalovirus R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 16/5218 16/10654 1.0833245890553573e-5 2.9791426199022326e-5 1.1381144428603776e-5 1869/5928/7027/5934/890/983/7029/286826/91750/1874/55957/4605/1875/5933/3065/132660 16 Human_cytomegalovirus R-HSA-1433559 Regulation of KIT signaling 16/5218 16/10654 1.0833245890553573e-5 2.9791426199022326e-5 1.1381144428603776e-5 5777/5578/2534/2885/10603/3815/9306/6714/7525/3932/10019/8651/4067/6654/867/4254 16 Human_cytomegalovirus R-HSA-156711 Polo-like kinase mediated events 16/5218 16/10654 1.0833245890553573e-5 2.9791426199022326e-5 1.1381144428603776e-5 5928/7465/993/2305/9133/286826/891/91750/55957/5347/4605/1063/9088/2033/995/132660 16 Human_cytomegalovirus R-HSA-193639 p75NTR signals via NF-kB 16/5218 16/10654 1.0833245890553573e-5 2.9791426199022326e-5 1.1381144428603776e-5 4790/8878/4792/3654/3551/7314/8767/5970/6233/7189/7311/4804/5584/4615/7316/4803 16 Human_cytomegalovirus R-HSA-1963640 GRB2 events in ERBB2 signaling 16/5218 16/10654 1.0833245890553573e-5 2.9791426199022326e-5 1.1381144428603776e-5 4893/2064/145957/9542/2885/3845/3265/1839/2069/3084/6654/10718/1956/685/1950/2066 16 Human_cytomegalovirus R-HSA-1963642 PI3K events in ERBB2 signaling 16/5218 16/10654 1.0833245890553573e-5 2.9791426199022326e-5 1.1381144428603776e-5 5295/2064/145957/9542/2885/1839/5290/2065/2069/3084/10718/1956/2549/685/1950/2066 16 Human_cytomegalovirus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 16/5218 16/10654 1.0833245890553573e-5 2.9791426199022326e-5 1.1381144428603776e-5 7040/7314/50848/7046/2280/6233/57530/5590/7048/7311/387/57154/50855/23370/7316/56288 16 Human_cytomegalovirus R-HSA-5654219 Phospholipase C-mediated cascade: FGFR1 16/5218 16/10654 1.0833245890553573e-5 2.9791426199022326e-5 1.1381144428603776e-5 2250/5335/2253/8074/2260/2249/2248/2247/2246/2251/9365/8822/2254/26281/2255/27006 16 Human_cytomegalovirus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 16/5218 16/10654 1.0833245890553573e-5 2.9791426199022326e-5 1.1381144428603776e-5 8454/4790/3551/7314/8945/1326/8517/6233/79155/7311/6416/1147/5604/6500/7316/23291 16 Human_cytomegalovirus R-HSA-9614657 FOXO-mediated transcription of cell death genes 16/5218 16/10654 1.0833245890553573e-5 2.9791426199022326e-5 1.1381144428603776e-5 2308/65018/356/1387/4801/604/4303/4800/10370/6794/27113/2309/10018/4802/1649/2033 16 Human_cytomegalovirus R-HSA-75893 TNF signaling 35/5218 43/10654 1.1416989792435605e-5 3.133551974220142e-5 1.197103064314065e-5 7124/25999/7375/9530/10616/6868/1540/3551/7314/257397/81858/8737/55072/23118/841/8517/7128/10454/6233/8772/331/8717/330/27005/8567/7311/1147/7186/56957/6885/7316/7132/329/9099/7185 35 Human_cytomegalovirus R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 22/5218 24/10654 1.159274928874406e-5 3.169435145349832e-5 1.2108114229020367e-5 2237/1763/5982/5422/6117/10714/6118/5557/5985/5984/23649/5424/54107/5425/5111/6119/5427/5983/56655/57804/5426/5981 22 Human_cytomegalovirus R-HSA-5627123 RHO GTPases activate PAKs 22/5218 24/10654 1.159274928874406e-5 3.169435145349832e-5 1.2108114229020367e-5 2017/79784/4628/5062/5879/4638/4659/4771/801/5500/805/2316/10627/998/5058/4629/3984/4627/10398/4637/103910/808 22 Human_cytomegalovirus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 49/5218 65/10654 1.1875004012852361e-5 3.2403111724992486e-5 1.23788801521166e-5 3725/4436/472/5431/5435/5433/2965/5439/672/1386/11198/904/51497/2176/5438/1643/9656/2177/2068/7157/1025/2353/7936/6829/2963/5434/5436/4292/4331/2962/8812/1111/2071/5432/6917/5440/8621/902/5430/6749/545/5441/5395/9150/5437/51755/2968/1022/8178 49 Human_cytomegalovirus R-HSA-164938 Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 19/5218 20/10654 1.3565016986107761e-5 3.644951129091551e-5 1.3924716110689164e-5 162/1174/567/163/51606/161/10053/926/3932/1175/8907/940/1173/160/920/8905/164/130340/375 19 Human_cytomegalovirus R-HSA-167044 Signalling to RAS 19/5218 20/10654 1.3565016986107761e-5 3.644951129091551e-5 1.3924716110689164e-5 4893/5898/1432/5603/2885/3845/3265/9261/6714/4914/5600/6300/6464/7867/6654/5900/25759/53358/4803 19 Human_cytomegalovirus R-HSA-5654706 FRS-mediated FGFR3 signaling 19/5218 20/10654 1.3565016986107761e-5 3.644951129091551e-5 1.3924716110689164e-5 4893/2250/2885/2253/3845/3265/8823/8074/2249/2247/2246/5781/6654/8822/8817/2254/26281/10818/2261 19 Human_cytomegalovirus R-HSA-5654719 SHC-mediated cascade:FGFR4 19/5218 20/10654 1.3565016986107761e-5 3.644951129091551e-5 1.3924716110689164e-5 4893/9965/2264/2885/2253/3845/3265/8823/8074/2249/2247/2246/2251/6464/6654/8822/8817/2254/26281 19 Human_cytomegalovirus R-HSA-5654720 PI-3K cascade:FGFR4 19/5218 20/10654 1.3565016986107761e-5 3.644951129091551e-5 1.3924716110689164e-5 5295/9965/2264/2885/2253/5290/8823/8074/2249/2247/2246/2251/5781/2549/8822/8817/2254/26281/10818 19 Human_cytomegalovirus R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 19/5218 20/10654 1.3565016986107761e-5 3.644951129091551e-5 1.3924716110689164e-5 472/1387/51499/7159/637/27166/23368/7157/63970/55240/5366/84883/147923/94241/8626/7161/665/27113/581 19 Human_cytomegalovirus R-HSA-8876384 Listeria monocytogenes entry into host cells 19/5218 20/10654 1.3565016986107761e-5 3.644951129091551e-5 1.3924716110689164e-5 6456/30011/2885/7314/8027/2060/1500/6714/999/9146/6455/6233/4233/7311/1499/7316/867/10254/6457 19 Human_cytomegalovirus R-HSA-8964616 G beta:gamma signalling through CDC42 19/5218 20/10654 1.3565016986107761e-5 3.644951129091551e-5 1.3924716110689164e-5 2788/2782/2787/10681/2792/2785/2783/2784/2791/998/2786/5058/54331/59345/51764/94235/55970/2793/2790 19 Human_cytomegalovirus R-HSA-194315 Signaling by Rho GTPases 267/5218 455/10654 1.388154645493881e-5 3.722898554010256e-5 1.4222496718744328e-5 55839/11130/7984/398/71/6249/51517/5579/392/9735/7531/55789/5526/29/51807/2909/10971/5578/9212/347688/613/1894/388/7533/2810/147841/348995/54509/10381/57122/6280/1780/23122/3688/5048/57405/8655/10094/23279/5881/1432/2017/2491/9138/7846/23365/79784/1060/171177/9322/397/4628/51291/11004/8976/1855/2885/23433/9184/8826/10499/5518/8874/23332/25909/10726/81930/5062/55746/9411/2665/5879/5515/9181/25/79682/1072/10403/4638/25936/4659/10093/1856/10006/4771/389/5594/3619/64105/7534/94274/332/5528/6453/9828/6714/79902/3796/5519/81565/999/396/10810/5880/85360/91687/10376/57584/83540/7410/5580/7409/1857/128239/9055/4649/7514/147700/54820/29984/1729/6396/1535/5600/91614/801/64946/9793/30849/10109/5586/140735/9886/2664/5500/4221/805/3831/220134/5170/84617/4928/4688/9743/5590/114793/5903/55055/5747/80776/1783/401541/64411/2316/7532/10382/7074/10627/79172/7277/10451/79980/58480/6232/5501/50650/10152/6279/55288/54821/10092/9183/4650/1062/699/94134/22919/3895/5529/51143/998/695/354/6654/10097/57120/367/57381/10383/5347/387/6655/60/84790/84643/5058/7280/4629/7529/5595/1778/5516/5905/81929/3984/54908/55143/1495/1499/5525/4690/1058/991/79019/4627/10928/348235/80152/10458/1063/8379/1027/11214/1080/23421/55920/79023/23370/6242/1781/9824/10398/4085/5289/5585/5216/10552/81624/55166/23092/4637/51466/995/79003/391/23221/23028/89941/2/90627/5527/10096/7454/701/23380/9928/29941/3799/103910/57551/5296/5300/808/10095/1536/399/4952 267 Human_cytomegalovirus R-HSA-157118 Signaling by NOTCH 147/5218 235/10654 1.590324636607269e-5 4.256990662249116e-5 1.6262875511433152e-5 8454/5689/3725/79718/5682/892/4904/182/27327/3091/23385/5705/5709/9978/1869/5695/9759/9612/4609/11060/22938/5711/1387/4088/6907/5683/408/5699/6400/4853/5702/192669/83737/6868/9794/4343/9787/388585/5696/5691/28514/7314/5718/23286/79885/2648/9734/7027/55869/5700/5707/51564/487/55534/3280/84441/10013/7534/83933/4854/7091/8650/102/9861/5870/8850/5087/2173/5698/5692/5713/595/5710/3002/3066/7157/5719/6233/2324/7029/7089/26523/5663/1999/23129/7090/409/5706/10402/10460/10046/1024/5714/6772/10014/489/5688/5687/5708/59/26508/4855/7088/5704/23493/7311/1956/5694/4851/27161/5684/8841/5720/5584/23462/207/5690/5045/57690/5717/9491/6500/51548/10197/192670/488/7316/10213/1950/9611/6484/1871/5715/5701/5685/5686/2033/55294/3065/861/2683/23112/5716/1385/3516/5693/5721 147 Human_cytomegalovirus R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 34/5218 42/10654 1.9157854024505957e-5 5.118455116983755e-5 1.9553906734290513e-5 2788/2782/8826/2787/10411/5567/10681/112/5573/111/2792/2785/2783/2784/3710/2791/5568/5566/2641/2786/5577/54331/5575/59345/51764/94235/114/3708/55970/2778/2793/5576/5906/2790 34 Human_cytomegalovirus R-HSA-5357905 Regulation of TNFR1 signaling 28/5218 33/10654 1.985716044102191e-5 5.285232873527193e-5 2.0191043648118987e-5 7124/25999/7375/10616/1540/3551/7314/81858/8737/55072/841/8517/7128/6233/331/8717/330/27005/8567/7311/1147/7186/56957/7316/7132/329/9099/7185 28 Human_cytomegalovirus R-HSA-68962 Activation of the pre-replicative complex 28/5218 33/10654 1.985716044102191e-5 5.285232873527193e-5 2.0191043648118987e-5 5422/4174/84515/4998/10926/990/55388/6117/5001/6118/5557/4175/23649/4172/5000/8318/54107/4173/51053/6119/5427/81620/4176/56655/1017/8317/5426/4171 28 Human_cytomegalovirus R-HSA-111933 Calmodulin induced events 30/5218 36/10654 2.0372179832893674e-5 5.4018887391175695e-5 2.0636701148991314e-5 817/5578/5582/107/818/5567/112/5573/111/5613/5580/196883/115/801/805/3838/5568/113/5566/816/5577/109/815/5575/114/108/5576/1385/808/5137 30 Human_cytomegalovirus R-HSA-111997 CaM pathway 30/5218 36/10654 2.0372179832893674e-5 5.4018887391175695e-5 2.0636701148991314e-5 817/5578/5582/107/818/5567/112/5573/111/5613/5580/196883/115/801/805/3838/5568/113/5566/816/5577/109/815/5575/114/108/5576/1385/808/5137 30 Human_cytomegalovirus R-HSA-112382 Formation of RNA Pol II elongation complex 46/5218 61/10654 2.1664335564434683e-5 5.701917276162779e-5 2.1782892704240285e-5 5431/5435/5433/2965/5439/11198/904/51497/4300/80349/5438/2068/1025/23168/55677/7936/6829/123169/85403/2963/5434/5436/9646/79577/4331/2962/8812/2071/27125/5432/22916/55840/6917/5440/902/6830/5430/6749/5441/4686/9150/54623/5437/2968/1022/8178 46 Human_cytomegalovirus R-HSA-75955 RNA Polymerase II Transcription Elongation 46/5218 61/10654 2.1664335564434683e-5 5.701917276162779e-5 2.1782892704240285e-5 5431/5435/5433/2965/5439/11198/904/51497/4300/80349/5438/2068/1025/23168/55677/7936/6829/123169/85403/2963/5434/5436/9646/79577/4331/2962/8812/2071/27125/5432/22916/55840/6917/5440/902/6830/5430/6749/5441/4686/9150/54623/5437/2968/1022/8178 46 Human_cytomegalovirus R-HSA-1170546 Prolactin receptor signaling 15/5218 15/10654 2.2151624645319886e-5 5.701917276162779e-5 2.1782892704240285e-5 8454/6776/9978/3717/5618/8945/2690/5617/6777/5781/1442/2689/6500/25970/2688 15 Human_cytomegalovirus R-HSA-391903 Eicosanoid ligand-binding receptors 15/5218 15/10654 2.2151624645319886e-5 5.701917276162779e-5 2.1782892704240285e-5 5734/5737/2840/5732/165140/10800/1241/5731/11251/6915/5733/5729/57105/56413/5739 15 Human_cytomegalovirus R-HSA-430039 mRNA decay by 5' to 3' exoribonuclease 15/5218 15/10654 2.2151624645319886e-5 5.701917276162779e-5 2.1782892704240285e-5 80153/219988/51690/11157/23644/27258/57819/23658/167227/1656/27257/25804/55802/196513/54464 15 Human_cytomegalovirus R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 15/5218 15/10654 2.2151624645319886e-5 5.701917276162779e-5 2.1782892704240285e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Human_cytomegalovirus R-HSA-5099900 WNT5A-dependent internalization of FZD4 15/5218 15/10654 2.2151624645319886e-5 5.701917276162779e-5 2.1782892704240285e-5 5579/5578/1212/5582/163/161/1856/8322/7474/1213/1211/1175/1173/409/160 15 Human_cytomegalovirus R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 15/5218 15/10654 2.2151624645319886e-5 5.701917276162779e-5 2.1782892704240285e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Human_cytomegalovirus R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 15/5218 15/10654 2.2151624645319886e-5 5.701917276162779e-5 2.1782892704240285e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Human_cytomegalovirus R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 15/5218 15/10654 2.2151624645319886e-5 5.701917276162779e-5 2.1782892704240285e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Human_cytomegalovirus R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 15/5218 15/10654 2.2151624645319886e-5 5.701917276162779e-5 2.1782892704240285e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Human_cytomegalovirus R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 15/5218 15/10654 2.2151624645319886e-5 5.701917276162779e-5 2.1782892704240285e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Human_cytomegalovirus R-HSA-5637810 Constitutive Signaling by EGFRvIII 15/5218 15/10654 2.2151624645319886e-5 5.701917276162779e-5 2.1782892704240285e-5 5295/4893/5335/2885/3845/3265/5290/6464/6654/1956/2549/11140/1950/867/3320 15 Human_cytomegalovirus R-HSA-5637812 Signaling by EGFRvIII in Cancer 15/5218 15/10654 2.2151624645319886e-5 5.701917276162779e-5 2.1782892704240285e-5 5295/4893/5335/2885/3845/3265/5290/6464/6654/1956/2549/11140/1950/867/3320 15 Human_cytomegalovirus R-HSA-6785631 ERBB2 Regulates Cell Motility 15/5218 15/10654 2.2151624645319886e-5 5.701917276162779e-5 2.1782892704240285e-5 2064/145957/9542/1839/2065/2069/1729/3084/10718/387/1956/685/1950/51072/2066 15 Human_cytomegalovirus R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 15/5218 15/10654 2.2151624645319886e-5 5.701917276162779e-5 2.1782892704240285e-5 6456/30011/2885/7314/8027/2060/9146/6455/6233/4233/7311/7316/867/10254/6457 15 Human_cytomegalovirus R-HSA-195721 Signaling by WNT 199/5218 331/10654 2.3112389170770406e-5 5.938365684752688e-5 2.2686190676649403e-5 2788/8454/27123/9070/5689/857/5579/5682/1459/5526/1452/5578/1212/5929/5582/27327/1460/55737/143471/5705/6657/2775/8452/5530/55366/5709/9978/5695/1457/9559/4609/5881/5711/1387/5683/324/5699/8724/8312/2782/5702/192669/1855/163/5518/4343/25776/3845/6659/80351/5696/5691/4920/7314/5879/5515/2787/5718/8945/161/6662/51701/5700/122706/5707/1856/8549/1454/8322/23198/10681/9101/7471/7534/5528/7091/89780/2792/59349/9861/81847/5519/2932/9580/5698/5880/5692/5713/2785/2783/2784/5710/284654/8313/5719/6233/7474/1857/7514/4040/1213/3710/1211/7855/7089/331/8607/1175/26523/801/2791/4221/805/123169/1173/144165/7090/6597/864/4772/409/79577/5706/160/23401/8658/5714/6934/10524/5688/5687/5148/4919/5708/51339/5529/7088/2786/208/57680/5704/7311/387/5694/5516/57154/27161/815/5684/8295/5720/54331/7015/6885/1487/1499/5525/59345/139285/207/8085/5690/5532/57690/5717/9491/50855/6500/51764/94235/3708/10197/192670/64750/7316/10213/55970/5216/5715/5701/2793/1455/5685/5686/2033/54894/5534/3065/23112/5527/1488/5716/23072/808/9736/5693/5721/6259/2790 199 Human_cytomegalovirus R-HSA-391251 Protein folding 70/5218 101/10654 2.587700872305226e-5 6.636580743544185e-5 2.535356429389264e-5 2788/6000/9134/1459/2770/51807/1460/10381/2775/10576/1457/7846/2782/10574/10564/54461/10693/8877/2773/5201/2787/402/5204/10575/10681/898/10517/2792/26985/2785/10376/2783/2784/10238/7157/2771/2791/84617/2629/2781/8237/10382/7277/6774/26272/26270/5082/2786/10383/60/84790/22948/7280/10694/8841/54331/22803/59345/51764/94235/7203/908/55970/6902/346562/2793/6950/55294/6499/2790 70 Human_cytomegalovirus R-HSA-70171 Glycolysis 52/5218 71/10654 2.6090428742787342e-5 6.67914975815356e-5 2.5516189641271448e-5 23165/7167/5211/348995/57122/3099/23511/23279/23225/9972/5518/8021/55746/5515/2597/5567/10762/5528/79902/5519/9883/226/2821/2645/6396/129401/4928/5903/55706/7175/5568/4927/5566/2023/8086/5516/81929/9631/5315/79023/23636/5214/53371/5230/3098/9688/5210/5209/5213/10007/8480/5223 52 Human_cytomegalovirus R-HSA-110320 Translesion Synthesis by POLH 18/5218 19/10654 2.641946498496721e-5 6.738878025151056e-5 2.574436805361984e-5 5982/25898/6117/55666/7314/6118/5985/5984/6233/5111/6119/83932/5429/7311/5983/7316/7415/5981 18 Human_cytomegalovirus R-HSA-6804760 Regulation of TP53 Activity through Methylation 18/5218 19/10654 2.641946498496721e-5 6.738878025151056e-5 2.574436805361984e-5 133383/11200/472/79813/4194/56950/7314/7157/6233/10419/26013/7311/7316/2033/91875/133746/10919/4193 18 Human_cytomegalovirus R-HSA-437239 Recycling pathway of L1 37/5218 47/10654 2.6715496276639806e-5 6.789786779333727e-5 2.5938853500594606e-5 9252/71/7430/51807/347688/1785/10381/7846/6456/5962/163/6196/1759/6197/161/5594/8650/6714/10376/6195/1213/1211/1175/1173/84617/10382/7277/4478/160/26052/27330/3897/10383/24137/60/84790/7280 37 Human_cytomegalovirus R-HSA-9020591 Interleukin-12 signaling 37/5218 47/10654 2.6715496276639806e-5 6.789786779333727e-5 2.5938853500594606e-5 3593/5908/3313/6175/5898/3717/3181/4001/3594/4282/5062/1072/3592/6627/9049/27250/9987/3185/3458/5478/302/7297/6775/3595/4478/998/6648/3716/6888/3586/829/6647/6950/6845/375/5721/5034 37 Human_cytomegalovirus R-HSA-901042 Calnexin/calreticulin cycle 23/5218 26/10654 2.835899784122295e-5 7.194498911791336e-5 2.7484965190829645e-5 811/6400/51009/7314/9695/10956/91445/80267/6233/55741/23193/267/6048/821/56886/10206/84447/2923/7311/7844/7316/5589/11236 23 Human_cytomegalovirus R-HSA-72086 mRNA Capping 25/5218 29/10654 3.261929378835607e-5 8.245595270018913e-5 3.150044245648673e-5 5431/5435/5433/8732/2965/5439/5438/2068/6829/2963/5434/5436/4331/2962/2071/5432/22916/5440/902/5430/5441/4686/5437/2968/1022 25 Human_cytomegalovirus R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 25/5218 29/10654 3.261929378835607e-5 8.245595270018913e-5 3.150044245648673e-5 2308/84676/4089/4088/3630/56729/2538/847/3484/5443/3066/2645/5105/4303/23410/4287/2908/4852/6648/4087/25942/2309/6720/3065/10891 25 Human_cytomegalovirus R-HSA-442755 Activation of NMDA receptors and postsynaptic events 65/5218 93/10654 3.284465576500066e-5 8.287683748587978e-5 3.1661232023986674e-5 5563/4893/51807/817/347688/53632/10381/107/7846/6196/8874/6197/3845/3265/5879/5923/818/5567/5594/51422/5573/6714/10376/6195/5613/801/2891/4747/57576/805/5170/84617/3838/8573/2904/2890/10382/5568/7277/55327/5566/5571/27330/3084/816/5577/5562/10383/84790/5564/5565/7280/5595/815/28964/5575/114/5576/4137/2066/9647/88/1385/808/8536 65 Human_cytomegalovirus R-HSA-5689896 Ovarian tumor domain proteases 31/5218 38/10654 3.3934158871504606e-5 8.547280087849461e-5 3.2652961460011024e-5 7321/324/64135/7187/7314/8737/8767/55611/8517/983/2099/23586/7128/7157/6233/55593/84282/10318/7706/79155/79589/7189/7311/387/56957/10392/57506/7316/7415/5728/78990 31 Human_cytomegalovirus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 27/5218 32/10654 3.46980009666008e-5 8.708517889656672e-5 3.3268934222596886e-5 892/4609/4089/22938/4088/1030/904/7314/5054/7027/6667/4092/6233/1025/7029/4221/3726/1024/8812/1874/4087/7311/7316/1875/5933/3065/25937 27 Human_cytomegalovirus R-HSA-73863 RNA Polymerase I Transcription Termination 27/5218 32/10654 3.46980009666008e-5 8.708517889656672e-5 3.3268934222596886e-5 5435/2965/64425/30834/2068/9533/5434/9015/79101/221830/7270/4331/9013/2071/10849/6908/5440/902/9014/25885/5441/51082/7343/5437/2968/84172/1022 27 Human_cytomegalovirus R-HSA-432720 Lysosome Vesicle Biogenesis 29/5218 35/10654 3.4982400988165305e-5 8.764274126572376e-5 3.348193838724943e-5 8906/162/27243/1212/1174/1785/408/6456/3312/10053/9146/4074/6844/1213/1211/23431/8907/351/9179/9829/8905/8673/164/130340/2647/81567/10717/6845/375 29 Human_cytomegalovirus R-HSA-198753 ERK/MAPK targets 20/5218 22/10654 4.091794389641307e-5 1.0160928572513158e-4 3.881754261777979e-5 9252/1848/1432/6196/5518/6197/51231/5515/1849/5594/5528/5519/5598/4208/6195/5600/5595/5516/1845/4205 20 Human_cytomegalovirus R-HSA-389357 CD28 dependent PI3K/Akt signaling 20/5218 22/10654 4.091794389641307e-5 1.0160928572513158e-4 3.881754261777979e-5 5295/941/2534/2475/1326/5290/9020/10000/3932/940/253260/5170/64223/8503/208/79109/207/55615/942/5296 20 Human_cytomegalovirus R-HSA-5654712 FRS-mediated FGFR4 signaling 20/5218 22/10654 4.091794389641307e-5 1.0160928572513158e-4 3.881754261777979e-5 4893/9965/2264/2885/2253/3845/3265/8823/8074/2249/2247/2246/2251/5781/6654/8822/8817/2254/26281/10818 20 Human_cytomegalovirus R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 20/5218 22/10654 4.091794389641307e-5 1.0160928572513158e-4 3.881754261777979e-5 3725/7531/356/7001/4001/823/2801/993/351/6648/1020/4000/994/2309/10018/831/824/995/8851/5052 20 Human_cytomegalovirus R-HSA-8863678 Neurodegenerative Diseases 20/5218 22/10654 4.091794389641307e-5 1.0160928572513158e-4 3.881754261777979e-5 3725/7531/356/7001/4001/823/2801/993/351/6648/1020/4000/994/2309/10018/831/824/995/8851/5052 20 Human_cytomegalovirus R-HSA-4086398 Ca2+ pathway 46/5218 62/10654 4.416455034132081e-5 1.086361778472382e-4 4.150200873201161e-5 2788/5578/27327/2775/5530/2782/192669/4343/3845/2787/51701/8322/10681/2792/2785/2783/2784/7474/3710/7855/26523/801/2791/805/4772/6934/5148/2786/27161/815/54331/6885/1499/59345/5532/57690/51764/94235/3708/192670/55970/2793/5534/23112/808/2790 46 Human_cytomegalovirus R-HSA-2559583 Cellular Senescence 123/5218 195/10654 4.436228322460322e-5 1.086361778472382e-4 4.150200873201161e-5 1912/3725/9134/2077/11065/4790/7321/6045/8697/27327/80012/7295/5925/472/79813/3576/2114/1869/1911/26277/4194/1031/5928/1432/4683/23512/57332/192669/8900/51529/4001/29945/8091/51434/1030/6196/4343/6197/29882/4217/54386/3569/7314/996/7014/5601/5606/7027/2146/5594/898/890/5970/9261/6667/51433/5598/84733/119504/6195/7157/7324/64682/6233/2353/7029/8726/5600/26523/5608/6015/1019/9448/246184/1029/8535/5931/7013/1051/8881/6774/7867/3552/10524/5602/10393/1870/51343/7311/25906/3397/57634/648/23466/3456/2113/6416/23523/5595/1017/25913/3159/7290/10111/57690/1027/192670/3490/8550/29855/7316/1026/1871/65057/1021/25842/23135/23112/5609/5599/10919/4193/23043 123 Human_cytomegalovirus R-HSA-1250347 SHC1 events in ERBB4 signaling 14/5218 14/10654 4.5290792895119904e-5 1.086361778472382e-4 4.150200873201161e-5 4893/145957/9542/2885/3845/3265/1839/2069/6464/3084/6654/10718/685/2066 14 Human_cytomegalovirus R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 14/5218 14/10654 4.5290792895119904e-5 1.086361778472382e-4 4.150200873201161e-5 5861/2801/5594/983/8548/8615/9133/891/81876/5347/5595/5862/26003/64689 14 Human_cytomegalovirus R-HSA-169893 Prolonged ERK activation events 14/5218 14/10654 4.5290792895119904e-5 1.086361778472382e-4 4.150200873201161e-5 5605/1399/5594/4914/673/2889/7529/5595/5604/57498/10818/4803/1398/5906 14 Human_cytomegalovirus R-HSA-180336 SHC1 events in EGFR signaling 14/5218 14/10654 4.5290792895119904e-5 1.086361778472382e-4 4.150200873201161e-5 374/4893/7039/2885/3845/3265/1839/2069/255324/6464/6654/1956/685/1950 14 Human_cytomegalovirus R-HSA-198323 AKT phosphorylates targets in the cytosol 14/5218 14/10654 4.5290792895119904e-5 1.086361778472382e-4 4.150200873201161e-5 84335/7249/2932/10000/2931/23608/572/208/1147/842/207/1027/1026/4193 14 Human_cytomegalovirus R-HSA-3371568 Attenuation phase 14/5218 14/10654 4.5290792895119904e-5 1.086361778472382e-4 4.150200873201161e-5 3305/1387/3306/3312/3303/3337/3297/3281/3326/3304/10728/3320/2033/2288 14 Human_cytomegalovirus R-HSA-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase 14/5218 14/10654 4.5290792895119904e-5 1.086361778472382e-4 4.150200873201161e-5 107/5567/5573/5613/801/805/5568/5566/5577/5575/114/5576/1385/808 14 Human_cytomegalovirus R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 14/5218 14/10654 4.5290792895119904e-5 1.086361778472382e-4 4.150200873201161e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Human_cytomegalovirus R-HSA-4839744 truncated APC mutants destabilize the destruction complex 14/5218 14/10654 4.5290792895119904e-5 1.086361778472382e-4 4.150200873201161e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Human_cytomegalovirus R-HSA-4839748 AMER1 mutants destabilize the destruction complex 14/5218 14/10654 4.5290792895119904e-5 1.086361778472382e-4 4.150200873201161e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Human_cytomegalovirus R-HSA-5467337 APC truncation mutants have impaired AXIN binding 14/5218 14/10654 4.5290792895119904e-5 1.086361778472382e-4 4.150200873201161e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Human_cytomegalovirus R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 14/5218 14/10654 4.5290792895119904e-5 1.086361778472382e-4 4.150200873201161e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Human_cytomegalovirus R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 14/5218 14/10654 4.5290792895119904e-5 1.086361778472382e-4 4.150200873201161e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Human_cytomegalovirus R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 14/5218 14/10654 4.5290792895119904e-5 1.086361778472382e-4 4.150200873201161e-5 79370/7159/23368/332/64065/7157/1121/604/5875/8626/7161/10397/9540/5876 14 Human_cytomegalovirus R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 14/5218 14/10654 4.5290792895119904e-5 1.086361778472382e-4 4.150200873201161e-5 9134/57060/1869/8900/144455/898/890/7157/79733/1820/1017/25946/1027/1026 14 Human_cytomegalovirus R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 14/5218 14/10654 4.5290792895119904e-5 1.086361778472382e-4 4.150200873201161e-5 7159/51230/23368/5458/10000/7157/5457/54971/8626/208/7161/25946/207/10848 14 Human_cytomegalovirus R-HSA-8941856 RUNX3 regulates NOTCH signaling 14/5218 14/10654 4.5290792895119904e-5 1.086361778472382e-4 4.150200873201161e-5 182/22938/1387/9794/2648/55534/3280/84441/8850/864/10046/4851/2033/3516 14 Human_cytomegalovirus R-HSA-9027284 Erythropoietin activates RAS 14/5218 14/10654 4.5290792895119904e-5 1.086361778472382e-4 4.150200873201161e-5 4893/3717/2885/2056/8660/3845/3265/1399/2057/7409/6464/2889/4067/6654 14 Human_cytomegalovirus R-HSA-112043 PLC beta mediated events 41/5218 54/10654 4.617480144798984e-5 1.1056823203872396e-4 4.224010658776013e-5 2770/817/5578/5582/2775/107/2773/818/5567/5594/112/5573/111/5613/2771/5580/3710/196883/115/801/805/3838/2781/5568/113/5566/816/5577/109/815/5321/5575/114/3708/108/10768/346562/5576/1385/808/5137 41 Human_cytomegalovirus R-HSA-210993 Tie2 Signaling 17/5218 18/10654 5.1320819789424505e-5 1.2247409197205036e-4 4.678847263585357e-5 5295/4893/5291/2885/3845/3265/5290/5781/6464/7010/2888/2886/6654/285/5296/284/9046 17 Human_cytomegalovirus R-HSA-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 17/5218 18/10654 5.1320819789424505e-5 1.2247409197205036e-4 4.678847263585357e-5 8792/10673/8740/7187/51330/958/9020/8742/959/4055/8600/330/115650/4050/7186/329/4049 17 Human_cytomegalovirus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 22/5218 25/10654 5.159342296483338e-5 1.227086816460902e-4 4.687809234535893e-5 9252/1848/1432/6196/5518/6197/51231/5515/1849/5594/5528/9261/5519/5598/4208/6195/5600/5595/5516/1845/4205/1385 22 Human_cytomegalovirus R-HSA-429947 Deadenylation of mRNA 22/5218 25/10654 5.159342296483338e-5 1.227086816460902e-4 4.687809234535893e-5 26986/25904/1973/55571/57472/85456/29883/1981/1977/9924/5073/4850/255967/246175/4848/23019/1975/1974/4849/10605/9337/9775 22 Human_cytomegalovirus R-HSA-5675221 Negative regulation of MAPK pathway 32/5218 40/10654 5.310847458466642e-5 1.2609904252143392e-4 4.817330347521885e-5 4893/1844/1848/5526/5605/5037/5894/5518/4140/3845/3265/7314/5515/8844/1849/5594/5528/5519/6233/1843/369/673/5529/7311/5536/7529/5595/5516/5604/5525/7316/5527 32 Human_cytomegalovirus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 185/5218 309/10654 6.200555890511429e-5 1.4697613962693756e-4 5.614892893941769e-5 8454/5689/11065/9666/5682/8916/7321/51665/65264/9021/8697/26235/9817/9039/6478/143471/5705/57674/9690/8452/5709/9978/5695/23304/4734/7337/84676/7704/3093/5711/23327/51465/10616/5683/25898/5699/7428/5702/22954/83737/51529/10075/29945/8924/56658/51434/10425/25793/23295/54461/29882/7334/4591/7332/5696/5691/9820/55658/7314/996/9354/5718/197131/8945/51320/5700/122706/5707/23198/10533/140462/7323/10517/4008/11059/27252/51444/51433/9861/6502/5698/27246/5692/5713/79654/5710/9040/7324/5719/64682/8925/51191/6233/6047/868/127247/5930/26268/23608/55585/51132/23352/246184/142686/10193/5706/79876/26263/8881/7317/80196/84078/5714/26272/8651/64219/140458/5688/5687/26270/63893/118424/5708/55008/10422/63891/9246/10393/5704/4012/7327/51343/7311/7318/57520/5694/997/7325/140691/57154/5684/6737/8065/5720/84708/7319/26046/991/10273/7320/5690/223082/5717/9491/6500/26259/10197/7336/64750/23376/7316/10213/25831/7322/5715/9867/5701/23291/5685/5686/55294/135892/8453/80176/8139/5716/7064/23194/80204/27338/23014/90678/5693/5721/51676 185 Human_cytomegalovirus R-HSA-4551638 SUMOylation of chromatin organization proteins 51/5218 71/10654 7.369523300238822e-5 1.7439140851657582e-4 6.662231590308781e-5 1912/23165/6045/80012/348995/6613/57122/23511/9759/1911/23279/23225/23512/57332/1107/9972/6612/8021/55746/83746/10762/79902/9883/84733/3066/9063/6396/129401/7703/6015/8554/4928/5903/55706/7175/8535/4927/8086/7329/648/23468/81929/9631/79023/23636/53371/9688/7341/3065/6304/8480 51 Human_cytomegalovirus R-HSA-445144 Signal transduction by L1 19/5218 21/10654 7.64229534108487e-5 1.8024039933412894e-4 6.885679131260459e-5 1459/1460/4684/3688/1457/5605/3690/5879/5594/2260/7410/3685/3674/3678/3897/1956/5058/5595/5604 19 Human_cytomegalovirus R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 19/5218 21/10654 7.64229534108487e-5 1.8024039933412894e-4 6.885679131260459e-5 2237/5982/6117/10714/6118/328/5985/5984/5424/54107/5425/5111/6119/5427/5983/56655/57804/5426/5981 19 Human_cytomegalovirus R-HSA-73894 DNA Repair 198/5218 334/10654 7.867674761247838e-5 1.8524558635178858e-4 7.076891045586421e-5 2237/4436/221120/83990/151987/4350/9156/2074/1763/7486/4913/56852/10445/5982/11200/472/6613/7507/3981/5431/5435/9978/5433/26277/10980/64421/4683/2965/25898/84126/5439/10987/8900/8924/57599/2067/672/6612/6117/7334/10973/10714/55666/54386/91603/83695/7314/51514/7014/6118/2176/25/5888/322/328/83444/51588/51720/63967/9557/5531/9636/86/5438/11201/116028/890/9031/1643/7517/9656/51455/29844/2177/5985/2068/7157/5984/4595/4255/6233/7158/6047/55247/8607/7874/5884/5810/5424/5886/8451/8554/10450/8467/80010/124739/3838/5434/5436/2956/7515/54107/7013/4292/7706/51567/580/11073/5591/8450/4331/5425/641/5111/6119/83932/3364/22976/10524/5427/144715/1161/1642/5429/142/1111/2071/1069/7329/9246/79728/51426/2873/7311/7318/4968/23030/60/5536/8533/5983/2175/10038/2547/5432/51138/7528/56655/9318/1017/25913/6917/5440/5893/902/5883/27339/5430/10111/57804/7320/7520/675/51548/545/5441/7336/2072/29086/7316/6996/8314/5426/9100/10459/7415/5395/7341/5437/51008/10401/65057/2033/7398/2968/5932/2189/79184/56949/7156/5887/9716/5599/5981/1022/8178/50813/7508 198 Human_cytomegalovirus R-HSA-76009 Platelet Aggregation (Plug Formation) 31/5218 39/10654 8.769095302477278e-5 2.0612497806156942e-4 7.8745412522026e-5 5770/5908/2244/3690/2885/9564/10411/7094/6714/2335/1445/2266/2243/2147/5170/6464/5747/3674/1277/150/6850/6654/7450/7066/151/207/152/1398/2811/5906/1278 31 Human_cytomegalovirus R-HSA-204005 COPII-mediated vesicle transport 49/5218 68/10654 8.920022995979296e-5 2.0932320630564748e-4 7.996722370079685e-5 6811/23256/374/126003/10960/2153/10484/7039/5861/90411/3998/9632/79090/58485/1294/2801/22872/81562/8615/55014/83696/51128/27095/6399/7109/6396/1453/2890/10802/2157/966/11196/10282/8775/81876/51693/5537/9871/9919/51399/55291/122553/63908/22870/5265/8774/4905/64689/10427 49 Human_cytomegalovirus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 13/5218 13/10654 9.259160945186753e-5 2.1407058474257716e-4 8.178085287339783e-5 2064/9542/7314/2065/9101/10000/6233/10193/3084/208/7311/207/7316 13 Human_cytomegalovirus R-HSA-179812 GRB2 events in EGFR signaling 13/5218 13/10654 9.259160945186753e-5 2.1407058474257716e-4 8.178085287339783e-5 374/4893/7039/2885/3845/3265/1839/2069/255324/6654/1956/685/1950 13 Human_cytomegalovirus R-HSA-190375 FGFR2c ligand binding and activation 13/5218 13/10654 9.259160945186753e-5 2.1407058474257716e-4 8.178085287339783e-5 2250/2253/8823/8074/2249/2247/2246/2251/2263/8822/8817/2254/26281 13 Human_cytomegalovirus R-HSA-209543 p75NTR recruits signalling complexes 13/5218 13/10654 9.259160945186753e-5 2.1407058474257716e-4 8.178085287339783e-5 8878/3654/3551/7314/8767/6233/7189/7311/4804/5584/4615/7316/4803 13 Human_cytomegalovirus R-HSA-209560 NF-kB is activated and signals survival 13/5218 13/10654 9.259160945186753e-5 2.1407058474257716e-4 8.178085287339783e-5 4790/8878/4792/3654/3551/7314/5970/6233/7189/7311/4804/7316/4803 13 Human_cytomegalovirus R-HSA-5357786 TNFR1-induced proapoptotic signaling 13/5218 13/10654 9.259160945186753e-5 2.1407058474257716e-4 8.178085287339783e-5 7124/7375/1540/8737/841/7128/8772/8717/27005/7186/56957/7132/9099 13 Human_cytomegalovirus R-HSA-5654227 Phospholipase C-mediated cascade; FGFR3 13/5218 13/10654 9.259160945186753e-5 2.1407058474257716e-4 8.178085287339783e-5 2250/5335/2253/8823/8074/2249/2247/2246/8822/8817/2254/26281/2261 13 Human_cytomegalovirus R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13/5218 13/10654 9.259160945186753e-5 2.1407058474257716e-4 8.178085287339783e-5 7531/10971/7533/2810/11200/7465/7534/983/7532/891/1111/7529/995 13 Human_cytomegalovirus R-HSA-8847993 ERBB2 Activates PTK6 Signaling 13/5218 13/10654 9.259160945186753e-5 2.1407058474257716e-4 8.178085287339783e-5 2064/5753/145957/9542/1839/2065/2069/3084/10718/1956/685/1950/2066 13 Human_cytomegalovirus R-HSA-203927 MicroRNA (miRNA) biogenesis 21/5218 24/10654 9.341055979034666e-5 2.1490534017125506e-4 8.20997524129122e-5 5431/5435/5433/5439/192669/29102/5438/54487/57510/26523/23405/5434/5436/5901/5432/27161/5440/5430/5441/192670/5437 21 Human_cytomegalovirus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 21/5218 24/10654 9.341055979034666e-5 2.1490534017125506e-4 8.20997524129122e-5 1432/3654/7334/7314/257397/5606/8767/23118/8517/9261/10454/6233/5600/5608/7867/3656/7189/7311/6885/10392/7316 21 Human_cytomegalovirus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 21/5218 24/10654 9.341055979034666e-5 2.1490534017125506e-4 8.20997524129122e-5 374/7039/1839/5594/2069/10000/595/7514/2353/255324/5747/208/1956/5595/596/685/2309/207/1027/1950/1385 21 Human_cytomegalovirus R-HSA-112040 G-protein mediated events 41/5218 55/10654 9.567204551603929e-5 2.1974916816734635e-4 8.39502279706295e-5 2770/817/5578/5582/2775/107/2773/818/5567/5594/112/5573/111/5613/2771/5580/3710/196883/115/801/805/3838/2781/5568/113/5566/816/5577/109/815/5321/5575/114/3708/108/10768/346562/5576/1385/808/5137 41 Human_cytomegalovirus R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 16/5218 17/10654 9.940557100587469e-5 2.2684447970222296e-4 8.666083218289172e-5 356/929/8737/841/8797/8772/8717/8743/8837/8795/23643/7186/355/7099/353376/148022 16 Human_cytomegalovirus R-HSA-196299 Beta-catenin phosphorylation cascade 16/5218 17/10654 9.940557100587469e-5 2.2684447970222296e-4 8.666083218289172e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/23401/5529/5516/1499/5525/139285/5527 16 Human_cytomegalovirus R-HSA-5655862 Translesion synthesis by POLK 16/5218 17/10654 9.940557100587469e-5 2.2684447970222296e-4 8.666083218289172e-5 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/51426/7311/5983/7316/10459/5981 16 Human_cytomegalovirus R-HSA-5656121 Translesion synthesis by POLI 16/5218 17/10654 9.940557100587469e-5 2.2684447970222296e-4 8.666083218289172e-5 5982/6117/7314/6118/11201/51455/5985/5984/6233/5111/6119/7311/5983/7316/10459/5981 16 Human_cytomegalovirus R-HSA-113418 Formation of the Early Elongation Complex 27/5218 33/10654 1.0148178333170587e-4 2.2985510209323082e-4 8.781097276438467e-5 5431/5435/5433/2965/5439/51497/5438/2068/7936/6829/2963/5434/5436/4331/2962/2071/5432/22916/5440/902/5430/5441/4686/9150/5437/2968/1022 27 Human_cytomegalovirus R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 27/5218 33/10654 1.0148178333170587e-4 2.2985510209323082e-4 8.781097276438467e-5 5431/5435/5433/2965/5439/51497/5438/2068/7936/6829/2963/5434/5436/4331/2962/2071/5432/22916/5440/902/5430/5441/4686/9150/5437/2968/1022 27 Human_cytomegalovirus R-HSA-202433 Generation of second messenger molecules 27/5218 33/10654 1.0148178333170587e-4 2.2985510209323082e-4 8.781097276438467e-5 5335/3115/3113/3117/3127/5062/916/3702/3932/3120/3937/3123/3122/920/7535/5058/55740/9402/4690/3119/919/27040/915/917/51466/7408/7454 27 Human_cytomegalovirus R-HSA-2871809 FCERI mediated Ca+2 mobilization 27/5218 33/10654 1.0148178333170587e-4 2.2985510209323082e-4 8.781097276438467e-5 5335/5530/2885/4773/5336/7410/7409/3702/3710/801/805/6464/4772/3937/10451/6850/4067/695/6654/9402/5532/3708/10768/27040/5534/808/2207 27 Human_cytomegalovirus R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 23/5218 27/10654 1.0219410078860972e-4 2.2985510209323082e-4 8.781097276438467e-5 5431/5435/5433/8732/2965/5439/5438/2068/6829/2963/5434/5436/4331/2962/2071/5432/5440/902/5430/5441/5437/2968/1022 23 Human_cytomegalovirus R-HSA-354192 Integrin alphaIIb beta3 signaling 23/5218 27/10654 1.0219410078860972e-4 2.2985510209323082e-4 8.781097276438467e-5 5770/5908/2244/3690/2885/9564/10411/7094/6714/2335/1445/2266/2243/5170/6464/5747/3674/6850/6654/7450/207/1398/5906 23 Human_cytomegalovirus R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 23/5218 27/10654 1.0219410078860972e-4 2.2985510209323082e-4 8.781097276438467e-5 356/836/929/26060/1612/8737/841/8797/1613/8772/8717/8743/8837/8795/23643/7186/842/355/7099/23604/1630/353376/148022 23 Human_cytomegalovirus R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 23/5218 27/10654 1.0219410078860972e-4 2.2985510209323082e-4 8.781097276438467e-5 5431/5435/5433/8732/2965/5439/5438/2068/6829/2963/5434/5436/4331/2962/2071/5432/5440/902/5430/5441/5437/2968/1022 23 Human_cytomegalovirus R-HSA-9006921 Integrin signaling 23/5218 27/10654 1.0219410078860972e-4 2.2985510209323082e-4 8.781097276438467e-5 5770/5908/2244/3690/2885/9564/10411/7094/6714/2335/1445/2266/2243/5170/6464/5747/3674/6850/6654/7450/207/1398/5906 23 Human_cytomegalovirus R-HSA-4090294 SUMOylation of intracellular receptors 25/5218 30/10654 1.042685066610792e-4 2.341468219757568e-4 8.945052783314275e-5 7068/6613/9759/8856/7067/6612/5914/7421/10062/51588/2516/2099/2494/9063/8554/5241/2908/9971/7329/367/5468/4306/7341/10401/6256 25 Human_cytomegalovirus R-HSA-383280 Nuclear Receptor transcription pathway 39/5218 52/10654 1.1302774445959155e-4 2.53009641016065e-4 9.665664365969591e-5 7068/5915/6097/5469/2104/9612/8856/2101/7067/5914/8431/7421/10062/7025/2516/2099/7101/2494/2103/6257/190/5241/7182/3172/10002/2063/9970/2908/9971/29982/367/5468/2100/4306/9611/3164/6256/6258/5916 39 Human_cytomegalovirus R-HSA-75153 Apoptotic execution phase 39/5218 52/10654 1.1302774445959155e-4 2.53009641016065e-4 9.665664365969591e-5 2339/10059/660/836/324/9414/4001/3836/6709/840/5062/2934/22985/63967/841/100506658/7082/5339/28988/10134/999/5588/5580/839/1828/5747/118/1829/8428/3148/4000/3837/51765/1499/3146/329/4137/7431/6304 39 Human_cytomegalovirus R-HSA-6811440 Retrograde transport at the Trans-Golgi-Network 37/5218 49/10654 1.328644225904506e-4 2.9647085104176615e-4 1.1326002159266037e-4 400/60592/8674/3482/9382/6293/8675/339122/7110/10618/55275/51209/10466/9827/22836/5870/91949/4074/8677/51542/8775/9712/10244/9648/57589/25839/84316/63908/738/9367/10226/9341/57511/51560/8774/143187/4905 37 Human_cytomegalovirus R-HSA-9012852 Signaling by NOTCH3 37/5218 49/10654 1.328644225904506e-4 2.9647085104176615e-4 1.1326002159266037e-4 4904/182/23385/11060/22938/1387/9794/9787/388585/28514/7314/23286/2648/55534/3280/84441/4854/102/8850/5087/2173/6233/5663/23129/10460/10046/6772/26508/23493/7311/1956/4851/23462/7316/1950/2033/3516 37 Human_cytomegalovirus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 18/5218 20/10654 1.4210949697470254e-4 3.1609821759933835e-4 1.207582156050104e-4 7321/7334/3551/7314/11035/8737/8517/7323/6233/330/7098/7189/7311/1147/7316/7322/329/148022 18 Human_cytomegalovirus R-HSA-69186 Lagging Strand Synthesis 18/5218 20/10654 1.4210949697470254e-4 3.1609821759933835e-4 1.207582156050104e-4 2237/1763/5982/5422/6117/10714/6118/5557/5985/5984/23649/5424/5425/5111/6119/5983/57804/5981 18 Human_cytomegalovirus R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 58/5218 84/10654 1.4768647895494586e-4 3.2798511414599966e-4 1.2529933711767782e-4 7124/1052/4790/79718/892/5469/9612/1387/6907/4023/10499/23054/7040/85441/9282/23097/96764/51129/7471/3952/5970/6604/9439/896/9370/9412/5105/1019/9440/6721/9862/1051/1050/1024/9314/9968/9477/6517/80306/8841/5468/29079/6720/6837/688/9611/81857/2033/9967/7026/6256/10498/948/112950/27332/8202/8648/10891 58 Human_cytomegalovirus R-HSA-8854214 TBC/RABGAPs 35/5218 46/10654 1.5523430860990732e-4 3.442045772011803e-4 1.3149561823400357e-4 5869/57533/51762/9230/83452/4943/5868/7249/23637/5870/8408/64786/4218/7879/26088/27342/9363/382/9135/5867/10133/11345/7248/23062/11337/51256/8766/51560/11021/79735/81631/5878/23163/338382/57465 35 Human_cytomegalovirus R-HSA-70326 Glucose metabolism 62/5218 91/10654 1.613005773066544e-4 3.5709310196190155e-4 1.3641938928119895e-4 23165/7167/2806/5211/348995/57122/3099/6576/23511/23279/23225/9972/5518/2538/4191/8021/55746/5515/2597/5567/10762/5528/79902/5519/9883/226/2821/2645/6396/129401/5105/4928/5903/55706/7175/2203/5568/2805/4927/5566/2023/4190/8086/5516/81929/9631/5091/5315/79023/23636/5214/53371/5230/10165/3098/9688/5210/5209/5213/10007/8480/5223 62 Human_cytomegalovirus R-HSA-3247509 Chromatin modifying enzymes 164/5218 274/10654 1.6192917791974862e-4 3.5736094437461766e-4 1.365217124517267e-4 9643/9070/1810/4790/79718/64769/80314/10474/9112/10445/5929/79813/7403/54556/23338/84289/9612/6603/5926/9767/27097/5928/1387/56950/3717/6907/23512/1107/79084/10943/57492/26610/6881/10499/1386/9575/55689/3054/51230/10284/55257/8089/55170/54014/23774/84661/8464/9869/6314/196528/2648/23186/55869/84193/2146/1788/51147/6871/23569/86/83933/5970/51562/51412/64426/79685/8850/55352/27154/57459/6604/8289/84159/56943/6602/55929/595/7994/8473/23522/3066/23067/10419/8607/8726/6883/51780/4791/55193/55904/6595/5077/1019/5927/29943/23326/84148/7862/6597/93624/9219/5931/8520/6599/8819/56970/11143/63976/1108/2122/84444/10524/55578/54815/23210/339287/55693/57504/58508/23030/57634/6880/60/6601/6187/53615/10362/4297/55140/10196/8295/8841/55167/11091/8242/5978/8085/6839/25855/6598/117143/10629/26009/9611/2874/10856/29072/10933/2033/6605/3065/23028/23135/10498/9757/80854/51317/9739/10902/3276/9913/8648/64754/10919 164 Human_cytomegalovirus R-HSA-4839726 Chromatin organization 164/5218 274/10654 1.6192917791974862e-4 3.5736094437461766e-4 1.365217124517267e-4 9643/9070/1810/4790/79718/64769/80314/10474/9112/10445/5929/79813/7403/54556/23338/84289/9612/6603/5926/9767/27097/5928/1387/56950/3717/6907/23512/1107/79084/10943/57492/26610/6881/10499/1386/9575/55689/3054/51230/10284/55257/8089/55170/54014/23774/84661/8464/9869/6314/196528/2648/23186/55869/84193/2146/1788/51147/6871/23569/86/83933/5970/51562/51412/64426/79685/8850/55352/27154/57459/6604/8289/84159/56943/6602/55929/595/7994/8473/23522/3066/23067/10419/8607/8726/6883/51780/4791/55193/55904/6595/5077/1019/5927/29943/23326/84148/7862/6597/93624/9219/5931/8520/6599/8819/56970/11143/63976/1108/2122/84444/10524/55578/54815/23210/339287/55693/57504/58508/23030/57634/6880/60/6601/6187/53615/10362/4297/55140/10196/8295/8841/55167/11091/8242/5978/8085/6839/25855/6598/117143/10629/26009/9611/2874/10856/29072/10933/2033/6605/3065/23028/23135/10498/9757/80854/51317/9739/10902/3276/9913/8648/64754/10919 164 Human_cytomegalovirus R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 20/5218 23/10654 1.6823773252953696e-4 3.6954559657034015e-4 1.4117658481417752e-4 5431/5435/5433/5439/51497/5438/7936/6829/2963/5434/5436/2962/5432/22916/5440/5430/5441/4686/9150/5437 20 Human_cytomegalovirus R-HSA-389948 PD-1 signaling 20/5218 23/10654 1.6823773252953696e-4 3.6954559657034015e-4 1.4117658481417752e-4 5777/3115/3113/3117/3127/5133/29126/1445/916/3932/5781/3120/3123/80380/3122/920/3119/919/915/917 20 Human_cytomegalovirus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 20/5218 23/10654 1.6823773252953696e-4 3.6954559657034015e-4 1.4117658481417752e-4 3654/7334/7314/257397/5601/8767/23118/8517/10454/6233/5602/3656/7189/7311/6416/6885/10392/7316/5609/5599 20 Human_cytomegalovirus R-HSA-1251985 Nuclear signaling by ERBB4 26/5218 32/10654 1.7132691781601182e-4 3.751606536313291e-4 1.4332169109271023e-4 2670/51741/23385/6776/10413/145957/6868/9542/6387/1839/6678/2069/23118/348/6714/2099/3925/5663/5241/3084/10718/685/9611/2066/6285/11033 26 Human_cytomegalovirus R-HSA-8941326 RUNX2 regulates bone development 26/5218 32/10654 1.7132691781601182e-4 3.751606536313291e-4 1.4332169109271023e-4 5925/9759/10413/4089/3549/25/5594/3280/10013/2737/865/6714/7525/10432/4091/1277/2736/23493/367/860/5595/8841/23462/4086/4094/25937 26 Human_cytomegalovirus R-HSA-5620920 Cargo trafficking to the periciliary membrane 38/5218 51/10654 1.7532421793903648e-4 3.833175448108127e-4 1.4643784793535083e-4 55763/79738/1260/1258/1262/10576/60412/192668/6010/2847/10575/9727/5310/8729/11336/117177/378/56623/4218/6102/6753/50807/5311/403/22948/55770/23265/10694/6608/10640/7203/8766/149371/6950/55212/200894/54536/8195 38 Human_cytomegalovirus R-HSA-8856688 Golgi-to-ER retrograde transport 86/5218 133/10654 1.7641266340734818e-4 3.850992714380562e-4 1.4711851652575263e-4 11014/51807/347688/5861/10381/1780/5048/8655/84516/832/55738/10112/636/7846/11004/10749/81930/54732/51164/60561/23299/8398/1315/3796/5870/11316/56992/8729/10376/1314/10540/3835/147700/378/9493/26286/26958/140735/3831/84364/22820/84617/11258/1783/55850/10382/93661/55860/830/3832/7277/10671/23303/1639/8775/81876/9183/1062/51143/10383/24137/84790/84643/10945/7280/829/22931/1778/5321/5050/63908/1781/22930/25782/10121/6836/547/51560/8774/381/4905/9276/3799/375/22818/372 86 Human_cytomegalovirus R-HSA-2172127 DAP12 interactions 33/5218 43/10654 1.8001611475259669e-4 3.9235710460008686e-4 1.498912084708765e-4 5295/4893/5335/7305/5291/3824/54209/567/2534/3822/2885/3133/3845/3265/5879/124599/5290/5336/23601/7410/3932/6464/3937/10451/6850/9436/22914/695/6654/9402/27040/100049587/5296 33 Human_cytomegalovirus R-HSA-170968 Frs2-mediated activation 12/5218 12/10654 1.8927389700091737e-4 4.025644214158484e-4 1.5379068431780696e-4 5605/1399/5594/4914/673/2889/7529/5595/5604/10818/4803/5906 12 Human_cytomegalovirus R-HSA-1839130 Signaling by activated point mutants of FGFR3 12/5218 12/10654 1.8927389700091737e-4 4.025644214158484e-4 1.5379068431780696e-4 2250/2253/8823/8074/2249/2247/2246/8822/8817/2254/26281/2261 12 Human_cytomegalovirus R-HSA-190873 Gap junction degradation 12/5218 12/10654 1.8927389700091737e-4 4.025644214158484e-4 1.5379068431780696e-4 71/1212/1785/2697/1759/4646/1601/1213/1211/1173/8218/60 12 Human_cytomegalovirus R-HSA-2029481 FCGR activation 12/5218 12/10654 1.8927389700091737e-4 4.025644214158484e-4 1.5379068431780696e-4 2268/2534/6714/7525/2214/2209/6850/4067/919/3055/917/2212 12 Human_cytomegalovirus R-HSA-2033514 FGFR3 mutant receptor activation 12/5218 12/10654 1.8927389700091737e-4 4.025644214158484e-4 1.5379068431780696e-4 2250/2253/8823/8074/2249/2247/2246/8822/8817/2254/26281/2261 12 Human_cytomegalovirus R-HSA-210990 PECAM1 interactions 12/5218 12/10654 1.8927389700091737e-4 4.025644214158484e-4 1.5379068431780696e-4 5777/5335/5175/2534/3690/3635/6714/7525/3685/3932/5781/4067 12 Human_cytomegalovirus R-HSA-3371511 HSF1 activation 12/5218 12/10654 1.8927389700091737e-4 4.025644214158484e-4 1.5379068431780696e-4 7531/1915/6117/6118/10013/3297/6119/3281/3326/10728/7415/3320 12 Human_cytomegalovirus R-HSA-381033 ATF6 (ATF6-alpha) activates chaperones 12/5218 12/10654 1.8927389700091737e-4 4.025644214158484e-4 1.5379068431780696e-4 811/3309/4801/8720/468/7184/7494/4800/22926/4802/1649/51360 12 Human_cytomegalovirus R-HSA-417957 P2Y receptors 12/5218 12/10654 1.8927389700091737e-4 4.025644214158484e-4 1.5379068431780696e-4 10161/64805/2840/5028/5029/53829/27334/9934/5032/5031/5030/2846 12 Human_cytomegalovirus R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 12/5218 12/10654 1.8927389700091737e-4 4.025644214158484e-4 1.5379068431780696e-4 834/55367/472/8738/7157/839/317/843/8626/7161/835/58484 12 Human_cytomegalovirus R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 12/5218 12/10654 1.8927389700091737e-4 4.025644214158484e-4 1.5379068431780696e-4 7159/23368/8797/7157/8626/7161/8795/8793/3486/355/8794/124446 12 Human_cytomegalovirus R-HSA-8984722 Interleukin-35 Signalling 12/5218 12/10654 1.8927389700091737e-4 4.025644214158484e-4 1.5379068431780696e-4 3717/3572/10148/3592/7297/6775/3595/821/6774/6772/3716/9466 12 Human_cytomegalovirus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 12/5218 12/10654 1.8927389700091737e-4 4.025644214158484e-4 1.5379068431780696e-4 7187/7314/29110/3661/6233/10010/3665/7098/7311/9641/7316/148022 12 Human_cytomegalovirus R-HSA-9020558 Interleukin-2 signaling 12/5218 12/10654 1.8927389700091737e-4 4.025644214158484e-4 1.5379068431780696e-4 6776/3558/3718/3932/6777/6464/6850/3716/2185/3561/3560/3559 12 Human_cytomegalovirus R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 12/5218 12/10654 1.8927389700091737e-4 4.025644214158484e-4 1.5379068431780696e-4 5295/5291/3717/2056/8660/5290/5294/2057/4067/5293/2549/23533 12 Human_cytomegalovirus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12/5218 12/10654 1.8927389700091737e-4 4.025644214158484e-4 1.5379068431780696e-4 64135/3551/8737/841/8517/23586/84282/8772/7706/843/1147/57506 12 Human_cytomegalovirus R-HSA-110312 Translesion synthesis by REV1 15/5218 16/10654 1.9192730596681476e-4 4.057562264283411e-4 1.5501004164539646e-4 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/7311/5983/7316/10459/5981 15 Human_cytomegalovirus R-HSA-190242 FGFR1 ligand binding and activation 15/5218 16/10654 1.9192730596681476e-4 4.057562264283411e-4 1.5501004164539646e-4 2250/2253/8074/2260/2249/2248/2247/2246/2251/9365/8822/2254/26281/2255/27006 15 Human_cytomegalovirus R-HSA-429958 mRNA decay by 3' to 5' exoribonuclease 15/5218 16/10654 1.9192730596681476e-4 4.057562264283411e-4 1.5501004164539646e-4 5393/23404/28960/10767/11340/80349/23016/118460/9652/51010/56915/22894/51013/6499/54512 15 Human_cytomegalovirus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 15/5218 16/10654 1.9192730596681476e-4 4.057562264283411e-4 1.5501004164539646e-4 929/7314/257397/23118/10454/6233/3656/7189/7311/23643/6885/7099/7316/353376/148022 15 Human_cytomegalovirus R-HSA-445355 Smooth Muscle Contraction 31/5218 40/10654 2.06808378762919e-4 4.365610154395652e-4 1.667783185478602e-4 140465/10580/3693/309/7169/5062/5829/4638/7094/7414/3672/859/800/302/801/805/10627/301/59/5058/4629/7170/2977/7168/7171/10174/10398/4637/103910/808/493829 31 Human_cytomegalovirus R-HSA-216083 Integrin cell surface interactions 58/5218 85/10654 2.4420193140131685e-4 5.147250290614583e-4 1.966391221967742e-4 3675/960/3696/5175/256076/3383/1280/1289/7448/6696/3688/3693/1290/2244/3690/3694/2200/1285/3655/1294/375790/7412/1284/50848/3683/3672/999/2335/1288/2266/3685/1292/2243/3791/1293/1291/1286/1287/3674/3684/3678/1277/4060/7450/3676/3371/1282/1299/1281/3673/682/8516/3687/131873/7057/1278/3689/961 58 Human_cytomegalovirus R-HSA-73887 Death Receptor Signalling 90/5218 141/10654 2.478230766596289e-4 5.215768190385015e-4 1.992566944741883e-4 7124/25999/7984/4790/7531/29/356/7375/9530/8878/1894/23385/4792/9138/836/23365/10616/3654/6868/8874/1540/3551/7314/5879/257397/9181/81858/8737/8767/55072/23118/841/8517/6453/9828/5970/8797/7128/396/10454/3066/6233/7410/7409/26574/8772/331/8717/8743/5663/84894/572/7074/330/10451/27005/50650/843/8837/8567/7189/6654/7311/387/6655/8795/1147/4804/57142/8841/7186/56957/6885/5584/10018/8793/835/355/11214/23421/23370/4615/7316/7132/329/9099/4803/3065/5599/7185 90 Human_cytomegalovirus R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 25/5218 31/10654 2.8740427243280424e-4 6.039779337095348e-4 2.307361872948358e-4 857/5526/1452/324/8312/1855/5518/5515/1856/7471/5528/89780/5519/2932/1857/4040/7855/23401/5529/5516/1499/5525/139285/1455/5527 25 Human_cytomegalovirus R-HSA-202427 Phosphorylation of CD3 and TCR zeta chains 19/5218 22/10654 3.0128801366893993e-4 6.322109139282674e-4 2.415219624830627e-4 5788/3115/3113/3117/55824/26191/3127/1445/916/3932/3120/3123/3122/920/5795/3119/919/915/917 19 Human_cytomegalovirus R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 23/5218 28/10654 3.05994826085973e-4 6.411320165610863e-4 2.4493006912583367e-4 2788/2770/2782/2787/10681/112/111/2792/2785/2783/2784/2771/2791/150/2786/54331/59345/51764/94235/55970/152/2793/2790 23 Human_cytomegalovirus R-HSA-2029485 Role of phospholipids in phagocytosis 21/5218 25/10654 3.129505281242932e-4 6.527916201466737e-4 2.4938435847409563e-4 5295/5335/5291/5290/5336/8398/5580/3710/2214/2209/6850/5337/23646/3708/919/10768/917/5296/5581/5338/2212 21 Human_cytomegalovirus R-HSA-8854691 Interleukin-20 family signaling 21/5218 25/10654 3.129505281242932e-4 6.527916201466737e-4 2.4938435847409563e-4 11009/6776/3717/282618/282617/3588/282616/3718/6777/6773/7297/5781/6775/50616/6774/6772/29949/163702/3716/58985/53832 21 Human_cytomegalovirus R-HSA-937041 IKK complex recruitment mediated by RIP1 21/5218 25/10654 3.129505281242932e-4 6.527916201466737e-4 2.4938435847409563e-4 7321/929/7334/3551/7314/11035/8737/8517/7323/6233/330/7189/7311/23643/1147/7099/7316/7322/329/353376/148022 21 Human_cytomegalovirus R-HSA-111447 Activation of BAD and translocation to mitochondria 14/5218 15/10654 3.692391483923199e-4 7.656682193466664e-4 2.925063248251693e-4 7531/10971/7533/2810/637/7534/10000/572/7532/208/7529/596/207/5534 14 Human_cytomegalovirus R-HSA-354194 GRB2:SOS provides linkage to MAPK signaling for Integrins 14/5218 15/10654 3.692391483923199e-4 7.656682193466664e-4 2.925063248251693e-4 5908/2244/3690/2885/7094/6714/2335/2266/2243/5747/3674/6654/7450/5906 14 Human_cytomegalovirus R-HSA-372708 p130Cas linkage to MAPK signaling for integrins 14/5218 15/10654 3.692391483923199e-4 7.656682193466664e-4 2.925063248251693e-4 5908/2244/3690/9564/7094/6714/2335/2266/2243/5747/3674/7450/1398/5906 14 Human_cytomegalovirus R-HSA-5654228 Phospholipase C-mediated cascade; FGFR4 14/5218 15/10654 3.692391483923199e-4 7.656682193466664e-4 2.925063248251693e-4 5335/9965/2264/2253/8823/8074/2249/2247/2246/2251/8822/8817/2254/26281 14 Human_cytomegalovirus R-HSA-1059683 Interleukin-6 signaling 11/5218 11/10654 3.8687191968134465e-4 7.883005251972984e-4 3.0115248831924307e-4 9021/3717/3569/3572/3570/7297/5781/6774/6772/3716/867 11 Human_cytomegalovirus R-HSA-1839122 Signaling by activated point mutants of FGFR1 11/5218 11/10654 3.8687191968134465e-4 7.883005251972984e-4 3.0115248831924307e-4 2250/2253/8074/2260/2249/2247/2246/2251/8822/2254/26281 11 Human_cytomegalovirus R-HSA-196025 Formation of annular gap junctions 11/5218 11/10654 3.8687191968134465e-4 7.883005251972984e-4 3.0115248831924307e-4 71/1212/1785/2697/1759/1601/1213/1211/1173/8218/60 11 Human_cytomegalovirus R-HSA-2586552 Signaling by Leptin 11/5218 11/10654 3.8687191968134465e-4 7.883005251972984e-4 3.0115248831924307e-4 3953/9021/6776/3717/8660/3667/3952/6777/5781/6774/25970 11 Human_cytomegalovirus R-HSA-3371378 Regulation by c-FLIP 11/5218 11/10654 3.8687191968134465e-4 7.883005251972984e-4 3.0115248831924307e-4 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355 11 Human_cytomegalovirus R-HSA-4755510 SUMOylation of immune response proteins 11/5218 11/10654 3.8687191968134465e-4 7.883005251972984e-4 3.0115248831924307e-4 4792/6612/51588/8517/5970/4791/10210/7329/9641/7341/10401 11 Human_cytomegalovirus R-HSA-5218900 CASP8 activity is inhibited 11/5218 11/10654 3.8687191968134465e-4 7.883005251972984e-4 3.0115248831924307e-4 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355 11 Human_cytomegalovirus R-HSA-5655291 Signaling by FGFR4 in disease 11/5218 11/10654 3.8687191968134465e-4 7.883005251972984e-4 3.0115248831924307e-4 5295/4893/5335/2264/2885/3845/3265/5290/6654/2549/10818 11 Human_cytomegalovirus R-HSA-69416 Dimerization of procaspase-8 11/5218 11/10654 3.8687191968134465e-4 7.883005251972984e-4 3.0115248831924307e-4 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355 11 Human_cytomegalovirus R-HSA-8875555 MET activates RAP1 and RAC1 11/5218 11/10654 3.8687191968134465e-4 7.883005251972984e-4 3.0115248831924307e-4 5908/3082/2885/1399/5879/85440/4233/2889/2549/1398/5906 11 Human_cytomegalovirus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 11/5218 11/10654 3.8687191968134465e-4 7.883005251972984e-4 3.0115248831924307e-4 7314/257397/23118/10454/6233/7098/7189/7311/6885/7316/148022 11 Human_cytomegalovirus R-HSA-9614399 Regulation of localization of FOXO transcription factors 11/5218 11/10654 3.8687191968134465e-4 7.883005251972984e-4 3.0115248831924307e-4 2308/10971/2810/7534/10000/7532/4303/208/7529/2309/207 11 Human_cytomegalovirus R-HSA-6807505 RNA polymerase II transcribes snRNA genes 51/5218 74/10654 3.9286285116744556e-4 7.993510035314499e-4 3.053740750632259e-4 6884/51585/5431/5435/5433/2960/5439/904/55197/2959/79871/5438/6667/29101/23248/1025/6829/2957/2963/5434/5436/6878/2962/51808/8812/5452/64859/6880/6908/80237/6619/6882/2961/5432/22916/6618/6877/5440/5430/5451/6617/5441/84524/4686/2958/5437/80789/51593/79035/1022/8178 51 Human_cytomegalovirus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 26/5218 33/10654 4.307517030434367e-4 8.751780633263475e-4 3.3434209805604343e-4 4790/4792/3654/7334/3551/7314/257397/8767/23118/8517/5970/10454/6233/4791/351/3656/7189/7311/1147/6885/10392/7316/4793/3146/6288/6285 26 Human_cytomegalovirus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 16/5218 18/10654 4.8408358073747873e-4 9.821176969428964e-4 3.7519598021667176e-4 929/7187/7314/29110/3661/6233/10010/5781/3665/7311/9641/23643/7099/7316/353376/148022 16 Human_cytomegalovirus R-HSA-422356 Regulation of insulin secretion 53/5218 78/10654 5.244945928412964e-4 0.0010625732183029428 4.059322028654335e-4 2788/2770/5578/2769/2782/3630/2776/8826/6513/2787/10411/5567/1131/10681/112/5573/111/2792/2785/2783/2784/2771/6844/2182/3710/2791/5568/150/6616/5566/2864/2641/6514/2786/5577/54331/5575/59345/51764/94235/114/3708/55970/2778/2767/10768/152/2793/5576/948/5906/9630/2790 53 Human_cytomegalovirus R-HSA-5696394 DNA Damage Recognition in GG-NER 29/5218 38/10654 5.27490954180339e-4 0.0010671081371924102 4.076646666457249e-4 10445/9978/10980/10987/7314/83444/86/1643/29844/6233/8607/5886/8451/8450/1642/142/1069/2873/7311/60/8533/10038/51138/7528/9318/7316/5887/50813/7508 29 Human_cytomegalovirus R-HSA-5621575 CD209 (DC-SIGN) signaling 18/5218 21/10654 5.362287583578291e-4 0.0010816763492375694 4.132301244470679e-4 9252/4893/4790/1387/2534/5894/3845/3265/5062/5567/5970/5568/5566/4067/30835/5971/5058/2033 18 Human_cytomegalovirus R-HSA-901032 ER Quality Control Compartment (ERQC) 18/5218 21/10654 5.362287583578291e-4 0.0010816763492375694 4.132301244470679e-4 6400/51009/7314/9695/10956/91445/80267/6233/55741/267/6048/56886/10206/84447/7311/7844/7316/11236 18 Human_cytomegalovirus R-HSA-933542 TRAF6 mediated NF-kB activation 20/5218 24/10654 5.42373596225486e-4 0.0010925064713669303 4.173675290583893e-4 4790/4792/64135/3551/4214/8517/5970/23586/84282/4791/351/7706/7189/1147/7186/57506/4793/3146/6288/6285 20 Human_cytomegalovirus R-HSA-5626467 RHO GTPases activate IQGAPs 25/5218 32/10654 7.019662532070591e-4 0.0013971432431457795 5.33747157033114e-4 71/6249/51807/347688/10381/7846/8826/5879/999/10376/128239/801/4221/805/84617/10382/7277/998/10383/60/84790/7280/1495/1499/808 25 Human_cytomegalovirus R-HSA-170670 Adenylate cyclase inhibitory pathway 13/5218 14/10654 7.075022246895887e-4 0.0013971432431457795 5.33747157033114e-4 2770/107/2773/112/111/2771/196883/115/113/109/114/108/346562 13 Human_cytomegalovirus R-HSA-174411 Polymerase switching on the C-strand of the telomere 13/5218 14/10654 7.075022246895887e-4 0.0013971432431457795 5.33747157033114e-4 5982/5422/10714/5557/5985/5984/23649/5424/5425/5111/5983/57804/5981 13 Human_cytomegalovirus R-HSA-177504 Retrograde neurotrophin signalling 13/5218 14/10654 7.075022246895887e-4 0.0013971432431457795 5.33747157033114e-4 1785/6456/163/1759/161/4914/1213/1211/1175/1173/160/26052/4803 13 Human_cytomegalovirus R-HSA-190322 FGFR4 ligand binding and activation 13/5218 14/10654 7.075022246895887e-4 0.0013971432431457795 5.33747157033114e-4 9965/2264/2253/8823/8074/2249/2247/2246/2251/8822/8817/2254/26281 13 Human_cytomegalovirus R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 13/5218 14/10654 7.075022246895887e-4 0.0013971432431457795 5.33747157033114e-4 4436/9156/6117/10714/6118/5424/2956/4292/5425/5111/6119/57804/5395 13 Human_cytomegalovirus R-HSA-69091 Polymerase switching 13/5218 14/10654 7.075022246895887e-4 0.0013971432431457795 5.33747157033114e-4 5982/5422/10714/5557/5985/5984/23649/5424/5425/5111/5983/57804/5981 13 Human_cytomegalovirus R-HSA-69109 Leading Strand Synthesis 13/5218 14/10654 7.075022246895887e-4 0.0013971432431457795 5.33747157033114e-4 5982/5422/10714/5557/5985/5984/23649/5424/5425/5111/5983/57804/5981 13 Human_cytomegalovirus R-HSA-69166 Removal of the Flap Intermediate 13/5218 14/10654 7.075022246895887e-4 0.0013971432431457795 5.33747157033114e-4 2237/1763/5422/6117/10714/6118/5557/23649/5424/5425/5111/6119/57804 13 Human_cytomegalovirus R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 13/5218 14/10654 7.075022246895887e-4 0.0013971432431457795 5.33747157033114e-4 4893/2909/5753/9564/3845/3265/5829/5879/5921/387/63916/1398/9844 13 Human_cytomegalovirus R-HSA-8983432 Interleukin-15 signaling 13/5218 14/10654 7.075022246895887e-4 0.0013971432431457795 5.33747157033114e-4 6776/2885/9846/3600/3718/6777/6464/6774/6654/3716/6655/3561/3560 13 Human_cytomegalovirus R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 13/5218 14/10654 7.075022246895887e-4 0.0013971432431457795 5.33747157033114e-4 79718/9612/6907/4204/801/805/5566/25942/8841/9611/2874/3065/808 13 Human_cytomegalovirus R-HSA-9005895 Pervasive developmental disorders 13/5218 14/10654 7.075022246895887e-4 0.0013971432431457795 5.33747157033114e-4 79718/9612/6907/4204/801/805/5566/25942/8841/9611/2874/3065/808 13 Human_cytomegalovirus R-HSA-918233 TRAF3-dependent IRF activation pathway 13/5218 14/10654 7.075022246895887e-4 0.0013971432431457795 5.33747157033114e-4 1387/64135/7187/29110/23586/3661/84282/3665/7706/9641/3456/57506/2033 13 Human_cytomegalovirus R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF) 39/5218 55/10654 7.830198692482423e-4 0.0015334412188570438 5.858167335795075e-4 79718/51141/10484/3638/5469/1387/6907/4801/9632/10499/23054/85441/31/96764/8720/2222/6667/6604/51128/6319/6721/10802/4800/32/1595/5901/4047/9871/3837/4802/6720/2194/6256/10498/51360/2224/4520/8648/10427 39 Human_cytomegalovirus R-HSA-110056 MAPK3 (ERK1) activation 10/5218 10/10654 7.906806284731631e-4 0.0015334412188570438 5.858167335795075e-4 3717/3569/3572/983/3570/7297/5781/3716/5595/5604 10 Human_cytomegalovirus R-HSA-1250342 PI3K events in ERBB4 signaling 10/5218 10/10654 7.906806284731631e-4 0.0015334412188570438 5.858167335795075e-4 5295/145957/9542/1839/5290/2069/3084/10718/685/2066 10 Human_cytomegalovirus R-HSA-174437 Removal of the Flap Intermediate from the C-strand 10/5218 10/10654 7.906806284731631e-4 0.0015334412188570438 5.858167335795075e-4 2237/1763/6117/10714/6118/5424/5425/5111/6119/57804 10 Human_cytomegalovirus R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 10/5218 10/10654 7.906806284731631e-4 0.0015334412188570438 5.858167335795075e-4 5563/53632/1432/51422/5600/6300/5571/5564/5565/10891 10 Human_cytomegalovirus R-HSA-381183 ATF6 (ATF6-alpha) activates chaperone genes 10/5218 10/10654 7.906806284731631e-4 0.0015334412188570438 5.858167335795075e-4 811/3309/4801/468/7184/7494/4800/22926/4802/1649 10 Human_cytomegalovirus R-HSA-390450 Folding of actin by CCT/TriC 10/5218 10/10654 7.906806284731631e-4 0.0015334412188570438 5.858167335795075e-4 10576/10574/10693/10575/60/22948/10694/7203/908/6950 10 Human_cytomegalovirus R-HSA-450341 Activation of the AP-1 family of transcription factors 10/5218 10/10654 7.906806284731631e-4 0.0015334412188570438 5.858167335795075e-4 3725/1432/1386/5601/5594/2353/5600/5602/5595/5599 10 Human_cytomegalovirus R-HSA-74749 Signal attenuation 10/5218 10/10654 7.906806284731631e-4 0.0015334412188570438 5.858167335795075e-4 3643/3630/2885/8660/3667/5594/6464/6654/5595/2887 10 Human_cytomegalovirus R-HSA-8853334 Signaling by FGFR3 fusions in cancer 10/5218 10/10654 7.906806284731631e-4 0.0015334412188570438 5.858167335795075e-4 5295/4893/2885/3845/3265/5290/6654/2549/10818/2261 10 Human_cytomegalovirus R-HSA-8875656 MET receptor recycling 10/5218 10/10654 7.906806284731631e-4 0.0015334412188570438 5.858167335795075e-4 3082/2885/1399/382/4233/5867/2549/53916/1398/23163 10 Human_cytomegalovirus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 10/5218 10/10654 7.906806284731631e-4 0.0015334412188570438 5.858167335795075e-4 7314/257397/23118/10454/6233/3656/7189/7311/6885/7316 10 Human_cytomegalovirus R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 10/5218 10/10654 7.906806284731631e-4 0.0015334412188570438 5.858167335795075e-4 2308/7295/1387/10628/23411/8850/4303/23410/2309/2033 10 Human_cytomegalovirus R-HSA-162588 Budding and maturation of HIV virion 23/5218 29/10654 7.920913298584751e-4 0.0015340640886392478 5.860546869726791e-4 51652/27243/51271/23327/29082/27183/92421/7314/137492/25978/51160/10015/91782/79720/51510/5478/6233/128866/7311/93343/7251/7316/9525 23 Human_cytomegalovirus R-HSA-110373 Resolution of AP sites via the multiple-nucleotide patch replacement pathway 21/5218 26/10654 8.739351494386177e-4 0.001687929616474038 6.448355517480812e-4 2237/5982/6117/10714/6118/328/5985/5984/5424/54107/5425/5111/6119/5427/142/5983/10038/56655/57804/5426/5981 21 Human_cytomegalovirus R-HSA-180024 DARPP-32 events 21/5218 26/10654 8.739351494386177e-4 0.001687929616474038 6.448355517480812e-4 5530/5499/5518/5515/5567/5142/5573/5528/5519/801/805/5568/5566/5577/1020/5516/5575/5532/5576/5534/808 21 Human_cytomegalovirus R-HSA-9034015 Signaling by NTRK3 (TRKC) 15/5218 17/10654 8.858403181738664e-4 0.0017039114316786939 6.50941044847348e-4 5295/4893/5335/2885/3845/3265/5290/3667/6714/4908/5800/6464/6654/4916/581 15 Human_cytomegalovirus R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 15/5218 17/10654 8.858403181738664e-4 0.0017039114316786939 6.50941044847348e-4 929/7314/257397/23118/10454/6233/3656/7189/7311/23643/6885/7099/7316/353376/148022 15 Human_cytomegalovirus R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 15/5218 17/10654 8.858403181738664e-4 0.0017039114316786939 6.50941044847348e-4 2308/857/2290/57060/4089/1647/4088/5934/4303/901/9314/4087/2309/1027/1026 15 Human_cytomegalovirus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 19/5218 23/10654 9.332768490811089e-4 0.001792706416788815 6.848631720836458e-4 7321/8239/9612/4089/23327/4088/7314/6497/51592/7323/5494/6233/142/4087/7311/64750/7316/9611/3065 19 Human_cytomegalovirus R-HSA-190241 FGFR2 ligand binding and activation 17/5218 20/10654 9.479284213254352e-4 0.0018134282842747456 6.927794955624962e-4 2250/2252/2253/8823/8074/2249/2248/2247/2246/2251/2263/8822/8817/2254/26281/2255/27006 17 Human_cytomegalovirus R-HSA-418217 G beta:gamma signalling through PLC beta 17/5218 20/10654 9.479284213254352e-4 0.0018134282842747456 6.927794955624962e-4 2788/2782/2787/10681/2792/2785/2783/2784/2791/2786/54331/59345/51764/94235/55970/2793/2790 17 Human_cytomegalovirus R-HSA-5625900 RHO GTPases activate CIT 17/5218 20/10654 9.479284213254352e-4 0.0018134282842747456 6.927794955624962e-4 388/79784/4628/5879/4659/389/9055/5500/10627/387/4629/4627/1027/10398/4637/9928/103910 17 Human_cytomegalovirus R-HSA-4791275 Signaling by WNT in cancer 26/5218 34/10654 9.777548836171766e-4 0.001867949628402964 7.136081490086085e-4 27123/5526/1452/324/8312/5518/80351/5515/8322/5528/89780/5519/2932/4040/7855/8658/6934/5529/5516/1487/1499/5525/139285/54894/5527/1488 26 Human_cytomegalovirus R-HSA-3000178 ECM proteoglycans 51/5218 76/10654 0.0010362977710103051 0.001977110110545406 7.553104564060276e-4 7042/256076/54829/1280/1289/7448/4684/3688/3693/3910/1290/3690/3694/7040/1285/7043/5054/633/6678/375790/1284/284217/4148/2335/1288/3685/1292/1293/1291/1286/1287/351/3674/1277/3912/3913/4060/2331/3371/1282/1299/1634/3915/1462/1281/3673/1758/8516/3687/131873/1278 51 Human_cytomegalovirus R-HSA-977444 GABA B receptor activation 29/5218 39/10654 0.0010961161859026956 0.0020855832293932373 7.967501721141926e-4 2788/2770/2550/107/9568/2782/2773/2787/112/111/2792/2785/2783/2784/2771/196883/115/113/2786/109/54331/3766/94235/114/108/55970/346562/2793/2790 29 Human_cytomegalovirus R-HSA-991365 Activation of GABAB receptors 29/5218 39/10654 0.0010961161859026956 0.0020855832293932373 7.967501721141926e-4 2788/2770/2550/107/9568/2782/2773/2787/112/111/2792/2785/2783/2784/2771/196883/115/113/2786/109/54331/3766/94235/114/108/55970/346562/2793/2790 29 Human_cytomegalovirus R-HSA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 12/5218 13/10654 0.0013494613475895118 0.0025435630219625602 9.71711052798197e-4 5925/5422/1869/28227/5518/5515/7027/5557/5519/7029/23649/5516 12 Human_cytomegalovirus R-HSA-171007 p38MAPK events 12/5218 13/10654 0.0013494613475895118 0.0025435630219625602 9.71711052798197e-4 4893/5898/1432/5603/3845/3265/9261/6714/5600/6300/7867/5900 12 Human_cytomegalovirus R-HSA-190239 FGFR3 ligand binding and activation 12/5218 13/10654 0.0013494613475895118 0.0025435630219625602 9.71711052798197e-4 2250/2253/8823/8074/2249/2247/2246/8822/8817/2254/26281/2261 12 Human_cytomegalovirus R-HSA-190372 FGFR3c ligand binding and activation 12/5218 13/10654 0.0013494613475895118 0.0025435630219625602 9.71711052798197e-4 2250/2253/8823/8074/2249/2247/2246/8822/8817/2254/26281/2261 12 Human_cytomegalovirus R-HSA-202670 ERKs are inactivated 12/5218 13/10654 0.0013494613475895118 0.0025435630219625602 9.71711052798197e-4 1848/5518/51231/5515/1849/5594/5528/5519/5598/5595/5516/1845 12 Human_cytomegalovirus R-HSA-5140745 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 12/5218 13/10654 0.0013494613475895118 0.0025435630219625602 9.71711052798197e-4 1212/163/4920/161/7474/1213/1211/7855/1175/1173/160/4919 12 Human_cytomegalovirus R-HSA-5658623 FGFRL1 modulation of FGFR1 signaling 12/5218 13/10654 0.0013494613475895118 0.0025435630219625602 9.71711052798197e-4 2250/2253/8074/2249/2248/2247/200734/8822/8817/2255/27006/161742 12 Human_cytomegalovirus R-HSA-167169 HIV Transcription Elongation 33/5218 46/10654 0.001430373294861608 0.002685287465553525 0.001025853689367413 5431/5435/5433/2965/5439/11198/904/51497/5438/2068/1025/7936/6829/2963/5434/5436/4331/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/4686/9150/5437/2968/1022/8178 33 Human_cytomegalovirus R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 33/5218 46/10654 0.001430373294861608 0.002685287465553525 0.001025853689367413 5431/5435/5433/2965/5439/11198/904/51497/5438/2068/1025/7936/6829/2963/5434/5436/4331/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/4686/9150/5437/2968/1022/8178 33 Human_cytomegalovirus R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 33/5218 46/10654 0.001430373294861608 0.002685287465553525 0.001025853689367413 5431/5435/5433/2965/5439/11198/904/51497/5438/2068/1025/7936/6829/2963/5434/5436/4331/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/4686/9150/5437/2968/1022/8178 33 Human_cytomegalovirus R-HSA-113510 E2F mediated regulation of DNA replication 18/5218 22/10654 0.0015934621094578236 0.002983503524091244 0.001139780428237609 5925/5422/1869/84515/4998/28227/5518/5001/5515/7027/5557/983/5519/7029/23649/5000/891/5516 18 Human_cytomegalovirus R-HSA-9613829 Chaperone Mediated Autophagy 18/5218 22/10654 0.0015934621094578236 0.002983503524091244 0.001139780428237609 2670/1915/5116/3043/3920/3312/11315/7314/10013/6233/3326/7311/1080/7316/10226/3320/200894/7431 18 Human_cytomegalovirus R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 14/5218 16/10654 0.0016104220453708495 0.003007260265095698 0.0011488561568958593 22938/1387/9794/2648/55534/3280/84441/8850/10046/3175/4851/2033/3516/6928 14 Human_cytomegalovirus R-HSA-418038 Nucleotide-like (purinergic) receptors 14/5218 16/10654 0.0016104220453708495 0.003007260265095698 0.0011488561568958593 10161/64805/2840/5028/5029/53829/27334/134/9934/5032/140/5031/5030/2846 14 Human_cytomegalovirus R-HSA-202430 Translocation of ZAP-70 to Immunological synapse 16/5218 19/10654 0.001663290221325027 0.003101871035265746 0.0011850000740287053 3115/3113/3117/26191/3127/916/3932/3120/3123/3122/920/7535/3119/919/915/917 16 Human_cytomegalovirus R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 28/5218 38/10654 0.0016905979792216678 0.0031486269242646933 0.0012028621099725318 5908/3313/6175/5898/3181/4001/4282/5062/1072/6627/9049/27250/9987/3185/3458/5478/302/6775/4478/998/6648/6888/3586/829/6647/6950/375/5721 28 Human_cytomegalovirus R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 34/5218 48/10654 0.0017364095852763647 0.003229675952535167 0.0012338250685896162 5431/5435/5433/2965/5439/11198/904/51497/5438/2068/1025/7936/6829/2963/5434/5436/4331/2962/8812/2071/5432/22916/6917/5440/902/5430/6749/5441/4686/9150/5437/2968/1022/8178 34 Human_cytomegalovirus R-HSA-8874081 MET activates PTK2 signaling 23/5218 30/10654 0.001821276088837375 0.0033830563760989764 0.0012924206101873332 3675/3082/1280/1289/3688/3910/1290/3918/284217/6714/2335/1302/5747/1277/3912/4233/3913/3915/1301/1281/3673/3914/1278 23 Human_cytomegalovirus R-HSA-9615710 Microautophagy 26/5218 35/10654 0.0020339437409225346 0.003773113026638905 0.0014414329819172253 51652/27243/5116/51271/3043/29082/3312/11315/92421/7314/137492/25978/51160/10013/91782/79720/6233/128866/7311/93343/7251/1080/7316/10226/200894/7431 26 Human_cytomegalovirus R-HSA-1368108 BMAL1:CLOCK,NPAS2 activates circadian gene expression 21/5218 27/10654 0.002116163138983697 0.003920470657485586 0.0014977276509981568 79718/28999/5469/1387/6907/2155/10499/23054/9575/85441/96764/5054/10135/6604/406/8553/4862/6256/10498/8648/551 21 Human_cytomegalovirus R-HSA-8940973 RUNX2 regulates osteoblast differentiation 19/5218 24/10654 0.002418709209932483 0.004475088787890849 0.0017096070354457418 5925/10413/25/5594/3280/10013/2737/865/6714/7525/1277/23493/367/860/5595/8841/23462/4094/25937 19 Human_cytomegalovirus R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 24/5218 32/10654 0.0024352407958512126 0.004499762520417988 0.001719033080093894 5295/5777/2534/30011/2885/973/5336/7409/3710/801/805/930/6850/4067/29760/695/6654/5293/4690/640/3708/10768/974/808 24 Human_cytomegalovirus R-HSA-9024446 NR1H2 and NR1H3-mediated signaling 33/5218 47/10654 0.002555641830321407 0.004700278798156182 0.001795635814786042 79718/27327/9612/64240/6907/192669/4343/1071/10062/344/64241/348/6257/26523/5105/6319/341/19/27161/8841/8204/57690/6720/192670/9611/2874/2194/2033/23028/6256/23112/8648/2172 33 Human_cytomegalovirus R-HSA-190373 FGFR1c ligand binding and activation 11/5218 12/10654 0.0025604501691660455 0.004700278798156182 0.001795635814786042 2250/2253/8074/2260/2249/2247/2246/2251/8822/2254/26281 11 Human_cytomegalovirus R-HSA-2197563 NOTCH2 intracellular domain regulates transcription 11/5218 12/10654 0.0025604501691660455 0.004700278798156182 0.001795635814786042 4853/9794/388585/55534/3280/84441/3002/10046/2033/1385/3516 11 Human_cytomegalovirus R-HSA-264870 Caspase-mediated cleavage of cytoskeletal proteins 11/5218 12/10654 0.0025604501691660455 0.004700278798156182 0.001795635814786042 836/6709/840/2934/841/5339/28988/839/118/4137/7431 11 Human_cytomegalovirus R-HSA-389359 CD28 dependent Vav1 pathway 11/5218 12/10654 0.0025604501691660455 0.004700278798156182 0.001795635814786042 941/2534/2885/5062/5879/7409/3932/940/998/5058/942 11 Human_cytomegalovirus R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 27/5218 37/10654 0.002586422351873111 0.00474177431176737 0.0018114882426084977 79718/27327/9612/64240/6907/192669/4343/1071/10062/344/64241/348/6257/26523/341/19/27161/8841/57690/192670/9611/2874/2033/23028/6256/23112/8648 27 Human_cytomegalovirus R-HSA-500657 Presynaptic function of Kainate receptors 17/5218 21/10654 0.002697651988937749 0.00493926397974558 0.0018869347291043594 2788/2782/2787/10681/2792/2785/2783/2784/2791/2786/54331/59345/51764/94235/55970/2793/2790 17 Human_hepatitis_A_virus_genotype_IB R-HSA-5620912 Anchoring of the basal body to the plasma membrane 95/1200 98/10654 2.955441240874785e-87 3.6470144912394845e-84 1.742154836726189e-84 115106/22995/55559/79867/11258/22981/8636/7531/10142/54903/80776/11190/203068/54801/7532/55125/1454/10382/85302/51134/95681/121441/7277/79441/5116/54806/9814/91147/5048/1781/23354/80321/8766/22832/146057/8655/9738/79598/983/1639/55722/4957/10121/9702/5566/79959/132320/347240/84131/7846/7840/7283/3320/22919/27077/22994/11064/4867/79600/10540/84902/10733/1069/4751/117177/5577/80254/57545/26005/54930/5518/26123/10383/55835/54820/5347/23322/9662/80184/55142/23332/1453/22897/9793/4218/5108/261734/8481/57787/93323/10806/51259/55755/9657/1778 95 Human_hepatitis_A_virus_genotype_IB R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 80/1200 82/10654 3.29713520955284e-74 1.356221616196068e-71 6.478581464384527e-72 114791/10844/115106/22995/55559/440145/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/653784/5048/1781/23354/728642/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/984/80097/10426/22994/11064/10540/10733/85378/1069/4751/5577/27175/80254/54930/5518/10383/55835/54820/5347/29922/9662/80184/55142/23332/1453/22897/27229/9793/5108/8481/93323/10806/55755/1778 80 Human_hepatitis_A_virus_genotype_IB R-HSA-380287 Centrosome maturation 80/1200 82/10654 3.29713520955284e-74 1.356221616196068e-71 6.478581464384527e-72 114791/10844/115106/22995/55559/440145/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/653784/5048/1781/23354/728642/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/984/80097/10426/22994/11064/10540/10733/85378/1069/4751/5577/27175/80254/54930/5518/10383/55835/54820/5347/29922/9662/80184/55142/23332/1453/22897/27229/9793/5108/8481/93323/10806/55755/1778 80 Human_hepatitis_A_virus_genotype_IB R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 81/1200 88/10654 3.8433873549041273e-69 1.1856849989879232e-66 5.6639392598587136e-67 8454/115106/8945/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/84962/55125/1454/10382/95681/6500/121441/7277/79441/5116/9814/5048/1781/23354/7316/80321/8655/9738/983/1639/6790/55722/4957/10121/9702/5566/79959/84131/23291/7846/7840/7283/3320/22919/22994/11064/10540/10733/79866/1069/4751/5577/6233/80254/7311/54930/5518/10133/10383/55835/54820/5347/9662/80184/55142/23332/1453/22897/9793/4218/5108/8481/93323/10806/55755/7314/1778 81 Human_hepatitis_A_virus_genotype_IB R-HSA-8854518 AURKA Activation by TPX2 71/1200 73/10654 1.498178448551626e-65 3.6975044110254135e-63 1.7662735393450748e-63 115106/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/22974/10382/3161/95681/121441/7277/79441/5116/9814/5048/1781/23354/80321/8655/9738/983/1639/6790/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/22994/11064/10540/10733/1069/4751/5577/80254/54930/5518/10383/55835/54820/5347/9662/80184/55142/23332/1453/22897/9793/5108/8481/93323/10806/55755/1778 71 Human_hepatitis_A_virus_genotype_IB R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 81/1200 94/10654 9.396815369486034e-64 1.932611694324294e-61 9.231958959495052e-62 114791/10844/115106/4926/22995/55559/79861/440145/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/653784/5048/1781/23354/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/347733/3320/22919/80097/10426/22994/11064/10540/10733/85378/1069/4751/5577/27175/80254/54930/5518/10383/55835/54820/5347/29922/9662/80184/55142/23332/1453/22897/27229/9793/5108/8481/93323/10806/55755/1778 81 Human_hepatitis_A_virus_genotype_IB R-HSA-380259 Loss of Nlp from mitotic centrosomes 68/1200 70/10654 1.1281344524088191e-62 1.7401473928406034e-60 8.31256964932814e-61 115106/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/5048/1781/23354/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/22994/11064/10540/10733/1069/4751/5577/80254/54930/5518/10383/55835/54820/5347/9662/80184/55142/23332/1453/22897/9793/5108/8481/93323/10806/55755/1778 68 Human_hepatitis_A_virus_genotype_IB R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 68/1200 70/10654 1.1281344524088191e-62 1.7401473928406034e-60 8.31256964932814e-61 115106/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/5048/1781/23354/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/22994/11064/10540/10733/1069/4751/5577/80254/54930/5518/10383/55835/54820/5347/9662/80184/55142/23332/1453/22897/9793/5108/8481/93323/10806/55755/1778 68 Human_hepatitis_A_virus_genotype_IB R-HSA-69275 G2/M Transition 117/1200 196/10654 1.7300272088259394e-61 2.3720595285457883e-59 1.1331172361900887e-59 114791/10844/8454/115106/1017/8945/22995/55559/5684/79861/440145/2305/11258/22981/8636/7531/51512/10142/11190/5707/203068/54801/7532/84962/63943/55125/1454/22974/10382/3161/95681/6500/121441/7277/79441/5116/9814/653784/5048/1781/23354/7316/728642/80321/8655/9738/983/1026/1639/6790/55722/4957/10121/9702/5566/79959/84131/5688/23291/7846/7840/7283/347733/3320/22919/984/5686/80097/2033/995/10426/5710/22994/11064/10540/7157/10733/85378/79866/1069/4751/5577/6233/3326/27175/80254/5716/7514/7311/54930/5518/10133/10383/55835/54820/5347/29922/9662/80184/55142/23332/1453/22897/7465/27229/9793/4218/5108/1022/8481/5693/93323/10806/55755/7314/5515/1778 117 Human_hepatitis_A_virus_genotype_IB R-HSA-453274 Mitotic G2-G2/M phases 117/1200 198/10654 8.386437965577437e-61 1.0348864449522557e-58 4.943584484971963e-59 114791/10844/8454/115106/1017/8945/22995/55559/5684/79861/440145/2305/11258/22981/8636/7531/51512/10142/11190/5707/203068/54801/7532/84962/63943/55125/1454/22974/10382/3161/95681/6500/121441/7277/79441/5116/9814/653784/5048/1781/23354/7316/728642/80321/8655/9738/983/1026/1639/6790/55722/4957/10121/9702/5566/79959/84131/5688/23291/7846/7840/7283/347733/3320/22919/984/5686/80097/2033/995/10426/5710/22994/11064/10540/7157/10733/85378/79866/1069/4751/5577/6233/3326/27175/80254/5716/7514/7311/54930/5518/10133/10383/55835/54820/5347/29922/9662/80184/55142/23332/1453/22897/7465/27229/9793/4218/5108/1022/8481/5693/93323/10806/55755/7314/5515/1778 117 Human_hepatitis_A_virus_genotype_IB R-HSA-5617833 Cilium Assembly 109/1200 201/10654 1.9128959796681403e-51 2.1459214899186228e-49 1.0250925824058932e-49 115106/10694/22995/55559/79867/79861/11258/22981/8636/7531/10142/54903/80776/11190/203068/54801/7532/10575/55125/1454/10382/85302/51134/95681/121441/7277/79441/10013/26146/5116/54806/9814/91147/5048/1781/23354/10576/80321/8766/22832/60412/146057/8655/9738/79598/983/1639/55722/149371/4957/10121/9702/5566/79959/132320/347240/84131/6950/7846/7840/7283/347733/3320/22919/27077/22994/11064/4867/79600/10540/84902/10733/1069/4751/117177/5577/80254/57545/26005/54930/5518/26123/10383/55835/54820/5347/23322/22948/9662/80184/55142/23332/1453/8195/22897/9793/4218/5108/261734/8481/57787/140735/93323/10806/51259/55755/9657/1778/55770 109 Human_hepatitis_A_virus_genotype_IB R-HSA-68877 Mitotic Prometaphase 106/1200 200/10654 9.676872319658763e-49 9.951050368715761e-47 4.753551314920094e-47 114791/10844/115106/4926/11130/22995/55559/81929/79861/54908/440145/11258/22981/25936/8636/7531/10142/80776/1459/55869/1783/11190/203068/54801/7532/55125/1454/10382/9212/95681/121441/1460/7277/79441/79980/5116/6232/332/1780/9814/653784/5885/5048/1781/23354/80321/8655/9738/1457/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/347733/3320/22919/80097/79003/8243/9126/11243/10426/22994/11064/51143/10540/10733/85378/1069/4751/5577/27175/80254/7514/54930/5518/10383/55835/54820/5347/29922/9662/80184/55142/23332/1453/22897/27229/9793/10726/5108/8481/140735/93323/10806/55755/5515/1778 106 Human_hepatitis_A_virus_genotype_IB R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 82/1200 129/10654 3.111524391095389e-46 2.953554691239777e-44 1.4108936510230105e-44 8454/23643/1147/3725/11035/8945/1326/351/9252/4790/6885/5606/5604/11213/7321/8737/10392/8767/29110/5594/4214/6500/330/23118/246330/10333/841/7099/8517/4615/7316/79155/7335/5970/4792/7096/9261/4793/3146/7867/7322/64127/5598/1432/329/23291/929/114609/3656/6195/57162/10454/3661/695/3654/7189/5609/6233/10010/51135/6196/7311/5518/7187/1386/8772/9641/6197/5599/353376/7334/7097/3551/5608/57161/4791/51231/7314/5595/5515/148022/257397 82 Human_hepatitis_A_virus_genotype_IB R-HSA-166166 MyD88-independent TLR4 cascade 70/1200 99/10654 2.327448094829813e-44 1.9147139660133262e-42 9.146462688454002e-43 8454/23643/1147/3725/11035/8945/1326/351/9252/4790/6885/5606/5604/7321/8737/10392/8767/29110/5594/6500/330/23118/841/7099/8517/7316/79155/7335/5970/4792/9261/4793/3146/7867/7322/64127/5598/1432/329/23291/929/3656/6195/10454/3661/3654/7189/5609/6233/10010/6196/7311/5518/7187/1386/8772/9641/6197/5599/353376/7334/3551/5608/4791/51231/7314/5595/5515/148022/257397 70 Human_hepatitis_A_virus_genotype_IB R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 70/1200 99/10654 2.327448094829813e-44 1.9147139660133262e-42 9.146462688454002e-43 8454/23643/1147/3725/11035/8945/1326/351/9252/4790/6885/5606/5604/7321/8737/10392/8767/29110/5594/6500/330/23118/841/7099/8517/7316/79155/7335/5970/4792/9261/4793/3146/7867/7322/64127/5598/1432/329/23291/929/3656/6195/10454/3661/3654/7189/5609/6233/10010/6196/7311/5518/7187/1386/8772/9641/6197/5599/353376/7334/3551/5608/4791/51231/7314/5595/5515/148022/257397 70 Human_hepatitis_A_virus_genotype_IB R-HSA-168898 Toll-like Receptor Cascades 88/1200 155/10654 8.450890736704543e-44 6.517749480683378e-42 3.113486060891147e-42 8454/23643/1147/3725/11035/8945/1326/351/9252/4790/6885/5606/5604/11213/7184/7321/8737/10392/8767/29110/5594/6271/4214/6500/330/23118/246330/10333/841/7099/8517/4615/7098/7316/79155/7335/5970/4792/7096/5289/9261/4793/6279/3146/7867/7322/64127/5598/1432/329/23291/929/114609/3656/6195/57162/10454/3661/695/3654/7189/5609/6233/10010/51135/6196/7311/5518/7187/1386/8772/9641/6197/5599/353376/7334/7097/3551/30849/5608/57161/4791/51231/7314/5595/5515/148022/257397 88 Human_hepatitis_A_virus_genotype_IB R-HSA-1852241 Organelle biogenesis and maintenance 125/1200 296/10654 1.2392452899511111e-43 8.99546286940983e-42 4.297073451223667e-42 115106/10694/5563/22995/55559/79867/79861/11258/22981/8636/7531/10142/54903/80776/11190/203068/54801/7532/10575/55125/1454/10382/85302/51134/95681/51422/121441/7277/79441/10013/26146/53632/5116/3313/54806/5465/9814/91147/5048/1781/23354/10576/80321/8766/22832/60412/146057/8655/9738/79598/983/1639/54205/55722/149371/4957/10121/9702/5566/79959/132320/347240/84131/1432/5571/1387/6950/7846/7840/7283/347733/3320/22919/27077/22994/11064/4867/79600/10540/84902/10733/1069/4751/117177/5577/80254/57545/26005/54930/5518/26123/10383/1386/55835/54820/5347/23322/22948/6742/3054/9662/80184/55142/23332/1453/8195/22897/5564/801/9793/5565/4218/5108/261734/8481/57787/140735/93323/814/10806/51259/55755/9657/1778/55770 125 Human_hepatitis_A_virus_genotype_IB R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 67/1200 94/10654 7.351264491936983e-43 5.039700212805687e-41 2.4074316464822864e-41 8454/1147/3725/11035/8945/1326/351/9252/4790/6885/5606/5604/7321/8737/10392/8767/29110/5594/6500/330/23118/841/8517/7098/7316/79155/7335/5970/4792/9261/4793/3146/7867/7322/64127/5598/1432/329/23291/3656/6195/10454/3661/3654/7189/5609/6233/10010/6196/7311/5518/7187/1386/8772/9641/6197/5599/7334/3551/5608/4791/51231/7314/5595/5515/148022/257397 67 Human_hepatitis_A_virus_genotype_IB R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 67/1200 95/10654 2.23071135895298e-42 1.3763489084739888e-40 6.574728215861414e-41 8454/23643/1147/3725/8945/1326/351/9252/4790/6885/5606/5604/11213/10392/8767/5594/4214/6500/23118/246330/10333/7099/8517/4615/7316/79155/7335/5970/4792/7096/9261/4793/3146/7867/64127/5598/1432/23291/929/114609/3656/6195/57162/10454/695/3654/7189/5609/6233/51135/6196/7311/5518/1386/6197/5599/7334/7097/3551/5608/57161/4791/51231/7314/5595/5515/257397 67 Human_hepatitis_A_virus_genotype_IB R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 67/1200 95/10654 2.23071135895298e-42 1.3763489084739888e-40 6.574728215861414e-41 8454/23643/1147/3725/8945/1326/351/9252/4790/6885/5606/5604/11213/10392/8767/5594/4214/6500/23118/246330/10333/7099/8517/4615/7316/79155/7335/5970/4792/7096/9261/4793/3146/7867/64127/5598/1432/23291/929/114609/3656/6195/57162/10454/695/3654/7189/5609/6233/51135/6196/7311/5518/1386/6197/5599/7334/7097/3551/5608/57161/4791/51231/7314/5595/5515/257397 67 Human_hepatitis_A_virus_genotype_IB R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 67/1200 98/10654 5.399565179354658e-41 3.028665196056204e-39 1.4467734451859372e-39 8454/23643/1147/3725/8945/1326/351/9252/4790/6885/5606/5604/11213/10392/8767/5594/4214/6500/23118/246330/10333/7099/8517/4615/7316/79155/7335/5970/4792/7096/9261/4793/3146/7867/64127/5598/1432/23291/929/114609/3656/6195/57162/10454/695/3654/7189/5609/6233/51135/6196/7311/5518/1386/6197/5599/7334/7097/3551/5608/57161/4791/51231/7314/5595/5515/257397 67 Human_hepatitis_A_virus_genotype_IB R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 67/1200 98/10654 5.399565179354658e-41 3.028665196056204e-39 1.4467734451859372e-39 8454/23643/1147/3725/8945/1326/351/9252/4790/6885/5606/5604/11213/10392/8767/5594/4214/6500/23118/246330/10333/7099/8517/4615/7316/79155/7335/5970/4792/7096/9261/4793/3146/7867/64127/5598/1432/23291/929/114609/3656/6195/57162/10454/695/3654/7189/5609/6233/51135/6196/7311/5518/1386/6197/5599/7334/7097/3551/5608/57161/4791/51231/7314/5595/5515/257397 67 Human_hepatitis_A_virus_genotype_IB R-HSA-2262752 Cellular responses to stress 159/1200 479/10654 1.3316652046856645e-39 7.144673315574391e-38 3.412963453656623e-38 1017/818/3303/7014/6118/3725/815/25913/81929/1019/5684/79861/4790/5241/11258/5606/64344/9448/3159/112399/7531/1029/1915/1783/7321/5707/2146/84962/817/6045/7422/10382/5594/93661/9530/3308/1027/10294/5925/55860/3091/830/7013/7277/10013/50488/545/3337/192670/3576/3313/10808/10671/1780/3490/847/4306/1781/7316/10935/3305/8655/6774/5970/84516/1026/1639/9261/9532/54205/832/6667/2289/10121/7415/6647/7867/4194/7322/6119/5598/1432/2932/10524/5688/1387/7846/3310/2908/3309/347733/3320/5686/2033/1021/7266/6195/6009/5710/6767/51143/3301/816/7428/192669/10540/9531/7157/8453/10963/22824/57600/5609/6233/3326/2475/5716/3306/1030/51343/6196/7311/367/2034/79400/10383/23411/6117/6197/29882/5599/54583/3304/3312/201163/4217/26523/405/5608/96459/3569/3297/57521/5693/10641/55466/140735/2288/5034/10728/829/7314/51164/51182/5595/4193/2950/1778/23043 159 Human_hepatitis_A_virus_genotype_IB R-HSA-4420097 VEGFA-VEGFR2 Pathway 66/1200 99/10654 2.5274049331152655e-39 1.2995073697767657e-37 6.207661239230477e-38 5295/26999/5170/5590/4893/857/5290/5335/71/558/5579/5291/1499/6461/5747/5567/10006/207/7422/10458/5578/3315/3708/1793/9261/10152/6714/7867/5566/8936/1432/10163/10810/10000/3320/55845/5063/2534/9475/3690/4846/3728/208/1398/5580/2475/23191/6093/3685/9844/2185/3791/387/9564/3845/3265/5058/801/3071/8877/5062/63916/5829/10787/5879/253260 66 Human_hepatitis_A_virus_genotype_IB R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 65/1200 97/10654 5.906997430041568e-39 2.9156939314685177e-37 1.3928078150834854e-37 8454/23643/1147/3725/8945/1326/351/9252/4790/6885/5606/5604/10392/8767/5594/4214/6500/23118/246330/7099/8517/4615/7316/79155/7335/5970/4792/5289/9261/4793/3146/7867/64127/5598/1432/23291/929/3656/6195/57162/10454/3654/7189/5609/6233/51135/6196/7311/5518/1386/6197/5599/353376/7334/3551/30849/5608/57161/4791/51231/7314/5595/5515/148022/257397 65 Human_hepatitis_A_virus_genotype_IB R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 63/1200 92/10654 1.1441233933675083e-38 5.4301856439057895e-37 2.59396396876844e-37 8454/23643/1147/3725/8945/1326/351/9252/4790/6885/5606/5604/10392/8767/5594/4214/6500/23118/246330/7099/8517/4615/7316/79155/7335/5970/4792/9261/4793/3146/7867/64127/5598/1432/23291/929/3656/6195/57162/10454/3654/7189/5609/6233/51135/6196/7311/5518/1386/6197/5599/353376/7334/3551/5608/57161/4791/51231/7314/5595/5515/148022/257397 63 Human_hepatitis_A_virus_genotype_IB R-HSA-194138 Signaling by VEGF 68/1200 107/10654 1.8284760938454825e-38 8.356812962241946e-37 3.991994590851735e-37 5295/26999/5170/5590/4893/857/5290/5335/71/558/5579/5291/1499/6461/5747/5567/10006/207/7422/10458/5578/3315/3708/8829/1793/9261/10152/6714/7867/5566/8936/1432/10163/10810/10000/3320/55845/5063/2534/9475/3690/4846/3728/208/1398/5580/2324/2475/23191/6093/3685/9844/2185/3791/387/9564/3845/3265/5058/801/3071/8877/5062/63916/5829/10787/5879/253260 68 Human_hepatitis_A_virus_genotype_IB R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 63/1200 93/10654 3.17128736208298e-38 1.3494374499346197e-36 6.44617394833564e-37 8454/23643/1147/3725/8945/1326/351/9252/4790/6885/5606/5604/10392/8767/5594/4214/6500/23118/246330/7099/8517/4615/7316/79155/7335/5970/4792/9261/4793/3146/7867/64127/5598/1432/23291/929/3656/6195/57162/10454/3654/7189/5609/6233/51135/6196/7311/5518/1386/6197/5599/353376/7334/3551/5608/57161/4791/51231/7314/5595/5515/148022/257397 63 Human_hepatitis_A_virus_genotype_IB R-HSA-975155 MyD88 dependent cascade initiated on endosome 63/1200 93/10654 3.17128736208298e-38 1.3494374499346197e-36 6.44617394833564e-37 8454/23643/1147/3725/8945/1326/351/9252/4790/6885/5606/5604/10392/8767/5594/4214/6500/23118/246330/7099/8517/4615/7316/79155/7335/5970/4792/9261/4793/3146/7867/64127/5598/1432/23291/929/3656/6195/57162/10454/3654/7189/5609/6233/51135/6196/7311/5518/1386/6197/5599/353376/7334/3551/5608/57161/4791/51231/7314/5595/5515/148022/257397 63 Human_hepatitis_A_virus_genotype_IB R-HSA-8953897 Cellular responses to external stimuli 159/1200 493/10654 7.585589388913327e-38 3.120205768639682e-36 1.4905017746636712e-36 1017/818/3303/7014/6118/3725/815/25913/81929/1019/5684/79861/4790/5241/11258/5606/64344/9448/3159/112399/7531/1029/1915/1783/7321/5707/2146/84962/817/6045/7422/10382/5594/93661/9530/3308/1027/10294/5925/55860/3091/830/7013/7277/10013/50488/545/3337/192670/3576/3313/10808/10671/1780/3490/847/4306/1781/7316/10935/3305/8655/6774/5970/84516/1026/1639/9261/9532/54205/832/6667/2289/10121/7415/6647/7867/4194/7322/6119/5598/1432/2932/10524/5688/1387/7846/3310/2908/3309/347733/3320/5686/2033/1021/7266/6195/6009/5710/6767/51143/3301/816/7428/192669/10540/9531/7157/8453/10963/22824/57600/5609/6233/3326/2475/5716/3306/1030/51343/6196/7311/367/2034/79400/10383/23411/6117/6197/29882/5599/54583/3304/3312/201163/4217/26523/405/5608/96459/3569/3297/57521/5693/10641/55466/140735/2288/5034/10728/829/7314/51164/51182/5595/4193/2950/1778/23043 159 Human_hepatitis_A_virus_genotype_IB R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 155/1200 473/10654 8.084278759940249e-38 3.2180645128278284e-36 1.537248253163511e-36 5295/26999/5170/5434/5590/1839/9252/4893/8065/6464/685/857/5290/3667/5335/71/558/5241/5579/4915/5291/5604/1499/2065/6461/5747/5567/10006/10273/207/7422/10458/5578/5594/10193/2069/2322/3315/2241/3178/23118/3708/2064/6778/2260/8829/9306/1793/7316/673/1950/5753/6774/11059/5289/4233/9261/4734/10413/10152/6714/2099/10818/7867/3910/5566/8936/5598/1432/2261/867/10163/5159/4670/4067/3717/4914/10810/10000/145957/3320/3084/55845/2335/5063/2534/9475/3690/4846/6195/3728/4803/8471/1111/2264/3630/2066/83737/208/4145/6654/9542/6233/2885/7525/1398/10718/5580/2324/2475/8660/23191/6093/3685/9844/6196/7311/3932/5518/2185/1213/3791/387/1956/8851/5581/9564/6197/3845/2549/3265/5058/801/3071/1020/30849/8877/5062/3480/4486/11140/51231/4916/7529/5156/63916/5829/10787/7314/5879/253260/5595/5515/2242/5607 155 Human_hepatitis_A_virus_genotype_IB R-HSA-9006925 Intracellular signaling by second messengers 118/1200 305/10654 1.1626224757540432e-36 4.483362922126529e-35 2.1416729816521846e-35 5295/1147/2308/818/5170/27161/3725/815/1839/5684/685/5290/3667/5335/2309/5291/5468/2065/1822/1459/842/572/5707/5567/2146/817/10273/207/6045/5578/5594/2069/4303/1027/7249/5582/1460/3708/2064/6199/192670/2260/4615/2100/7316/1950/1457/4233/8658/1026/4734/10645/6714/2099/10818/5566/84254/10014/2932/2261/5688/5159/3164/10000/145957/3084/5686/2534/5728/6009/2444/5710/6615/2264/816/3630/192669/3066/7157/1107/2066/8975/5613/5987/3654/7189/208/9542/5577/6233/2885/10718/5580/2475/5716/51135/8660/7311/3932/2931/5518/1386/1956/5581/331/2549/26523/801/57521/5693/814/5156/7314/5879/253260/5595/4193/5515 118 Human_hepatitis_A_virus_genotype_IB R-HSA-5663202 Diseases of signal transduction 132/1200 377/10654 1.4164068687768152e-35 5.231708078384109e-34 2.499152541068925e-34 5295/8454/4000/1147/2308/27044/818/5170/815/5434/7276/1839/5684/4893/6464/685/5290/3667/5335/71/2309/5291/5604/1499/2065/2648/10018/10142/55869/842/572/5707/283455/8844/817/207/1452/5594/3280/2069/9530/4303/613/1027/7249/6500/10533/10013/2064/6199/2260/2100/7316/673/1950/8315/6774/4233/9759/8658/1026/6714/2099/4609/10818/7415/10014/22938/5037/2932/2261/867/5688/1387/5159/7046/3717/3164/10000/145957/3320/3084/5686/2335/2534/2033/3690/408/55294/5728/5710/11064/2264/816/3066/4296/2066/5894/4087/208/6654/9542/6233/2885/10718/2475/5716/8660/7048/7311/51009/3932/2931/5518/1956/4140/3845/2549/3265/369/801/5693/11140/5245/7529/5156/7314/5879/253260/5595/4193/5515 132 Human_hepatitis_A_virus_genotype_IB R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 58/1200 85/10654 1.5262681590099508e-35 5.231708078384109e-34 2.499152541068925e-34 8454/1147/3725/8945/1326/351/9252/4790/6885/5606/5604/10392/8767/5594/4214/6500/23118/246330/8517/4615/7316/79155/7335/5970/4792/9261/4793/3146/7867/64127/5598/1432/23291/3656/6195/57162/10454/3654/7189/5609/6233/51135/6196/7311/5518/1386/6197/5599/7334/3551/5608/57161/4791/51231/7314/5595/5515/257397 58 Human_hepatitis_A_virus_genotype_IB R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 58/1200 85/10654 1.5262681590099508e-35 5.231708078384109e-34 2.499152541068925e-34 8454/1147/3725/8945/1326/351/9252/4790/6885/5606/5604/10392/8767/5594/4214/6500/23118/246330/8517/4615/7316/79155/7335/5970/4792/9261/4793/3146/7867/64127/5598/1432/23291/3656/6195/57162/10454/3654/7189/5609/6233/51135/6196/7311/5518/1386/6197/5599/7334/3551/5608/57161/4791/51231/7314/5595/5515/257397 58 Human_hepatitis_A_virus_genotype_IB R-HSA-975871 MyD88 cascade initiated on plasma membrane 58/1200 85/10654 1.5262681590099508e-35 5.231708078384109e-34 2.499152541068925e-34 8454/1147/3725/8945/1326/351/9252/4790/6885/5606/5604/10392/8767/5594/4214/6500/23118/246330/8517/4615/7316/79155/7335/5970/4792/9261/4793/3146/7867/64127/5598/1432/23291/3656/6195/57162/10454/3654/7189/5609/6233/51135/6196/7311/5518/1386/6197/5599/7334/3551/5608/57161/4791/51231/7314/5595/5515/257397 58 Human_hepatitis_A_virus_genotype_IB R-HSA-1227986 Signaling by ERBB2 43/1200 50/10654 3.844111955185239e-34 1.2820632845131311e-32 6.124331991191277e-33 5295/1839/4893/8065/6464/685/5290/5335/2065/10273/207/5578/10193/2069/2064/7316/1950/5753/6714/10000/145957/3320/3084/2534/2066/208/4145/6654/9542/6233/2885/7525/10718/5580/7311/387/1956/5581/3845/2549/3265/11140/7314 43 Human_hepatitis_A_virus_genotype_IB R-HSA-449147 Signaling by Interleukins 144/1200 461/10654 1.6528697008306153e-32 5.3674768705920504e-31 2.564008400180456e-31 5295/8454/7124/1147/2308/3725/7291/8945/1326/596/5684/351/9252/1072/6464/5290/1437/3667/4790/6885/5606/2309/5291/5604/4215/9049/11213/7412/7184/5707/10392/8767/356/207/5292/7422/29110/2625/1439/5594/8878/4582/821/6500/3091/23118/246330/8517/1438/6778/3576/4615/7534/3313/332/1436/4313/7316/6175/79155/6774/920/7335/5970/4792/3055/1026/9261/4793/4609/3146/6647/7867/5566/64127/7132/5598/1432/867/5688/6950/3558/4067/3717/23291/598/836/3320/5686/4843/2335/2534/84867/3656/595/6195/57162/5710/3458/10454/7157/3654/7189/5609/6654/6233/2885/7525/1398/3716/5716/51135/8660/604/6196/7311/3932/5518/2185/1386/5896/6197/8835/5599/4282/7334/3312/3551/6773/7297/5608/3569/57161/5062/4170/5693/4791/5034/51231/829/7314/5595/5515/257397 144 Human_hepatitis_A_virus_genotype_IB R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 44/1200 55/10654 3.1999907319874917e-32 1.0125098880186064e-30 4.83669314416463e-31 3303/79861/5241/11258/1783/10382/93661/10294/55860/830/7277/3337/10671/1780/4306/1781/3305/8655/84516/1639/832/2289/10121/7846/2908/347733/3320/51143/3301/10540/10963/3326/3306/367/10383/3304/3312/55466/140735/2288/10728/829/51164/1778 44 Human_hepatitis_A_virus_genotype_IB R-HSA-1632852 Macroautophagy 57/1200 95/10654 1.819767492605526e-30 5.613982714688048e-29 2.681762620681828e-29 5563/64422/7405/65018/1459/79065/9140/11337/22863/8878/60673/9821/10452/51422/7249/1460/10533/53632/84938/115201/26100/9474/7316/83734/11152/8655/5289/1457/440738/8678/6714/8408/5571/84971/6009/9776/55054/81631/55062/6233/2475/9804/7311/23710/84557/5562/11345/55626/3312/5564/23192/5565/30849/57521/7248/140735/7314 57 Human_hepatitis_A_virus_genotype_IB R-HSA-1257604 PIP3 activates AKT signaling 100/1200 264/10654 3.0702959855035476e-30 9.240842063686287e-29 4.4142894785160113e-29 5295/1147/2308/5170/27161/3725/1839/5684/685/5290/3667/2309/5291/5468/2065/1822/1459/842/572/5707/2146/10273/207/6045/5594/2069/4303/1027/7249/1460/2064/6199/192670/2260/4615/2100/7316/1950/1457/4233/8658/1026/4734/6714/2099/10818/10014/2932/2261/5688/5159/3164/10000/145957/3084/5686/2534/5728/6009/2444/5710/6615/2264/3630/192669/3066/7157/1107/2066/8975/5987/3654/7189/208/9542/6233/2885/10718/2475/5716/51135/8660/7311/3932/2931/5518/1386/1956/331/2549/26523/57521/5693/5156/7314/5879/253260/5595/4193/5515 100 Human_hepatitis_A_virus_genotype_IB R-HSA-9612973 Autophagy 64/1200 119/10654 3.2681682521485054e-30 9.60218957893156e-29 4.5869028100329895e-29 5563/64422/7405/65018/1459/1915/79065/9140/11337/22863/8878/60673/9821/10452/51422/7249/1080/1460/10533/10013/53632/84938/5116/115201/26100/9474/7316/83734/11152/8655/5289/1457/440738/8678/6714/8408/5571/3920/3320/84971/6009/9776/55054/81631/55062/6233/3326/2475/9804/7311/23710/84557/5562/11345/55626/3312/5564/23192/5565/30849/57521/7248/140735/7314 64 Human_hepatitis_A_virus_genotype_IB R-HSA-68886 M Phase 127/1200 395/10654 4.8951805864284024e-30 1.4048029868959648e-28 6.710651477111152e-29 114791/10844/4000/115106/4926/11130/22995/55559/81929/5684/79861/54908/440145/11258/5579/22981/25936/8636/7531/10142/80776/1459/55869/1783/11190/7321/5707/91754/203068/54801/7532/55125/1454/5578/10382/9212/5594/95681/5925/121441/1460/7277/79441/79980/5116/6232/332/1780/9814/653784/5885/5048/1781/23354/7316/80321/8655/9738/1457/983/1639/55722/4957/10121/9702/5566/79959/84131/5688/7846/7840/7283/347733/3320/22919/5686/80097/79003/8243/9126/11243/10426/5710/22994/11064/51143/10540/10733/85378/1069/4751/5577/6233/27175/80254/5716/7514/7311/54930/5518/10383/55835/54820/5347/29922/29882/9662/80184/55142/23332/1453/22897/27229/9793/10726/5108/8481/7112/5693/140735/93323/10806/55755/7314/5595/5515/1778 127 Human_hepatitis_A_virus_genotype_IB R-HSA-450294 MAP kinase activation 46/1200 64/10654 5.1971918540953e-30 1.4575760790803638e-28 6.962745067687483e-29 8454/1147/3725/8945/1326/9252/4790/6885/5606/5604/10392/8767/5594/6500/23118/8517/7316/79155/7335/9261/7867/64127/5598/1432/23291/3656/6195/10454/3654/7189/5609/6233/6196/7311/5518/1386/6197/5599/7334/3551/5608/51231/7314/5595/5515/257397 46 Human_hepatitis_A_virus_genotype_IB R-HSA-5357801 Programmed Cell Death 78/1200 181/10654 3.8351869980470085e-28 1.0516935012422241e-26 5.023870687500175e-27 23643/4000/11035/596/5684/7186/1612/51765/1499/10018/7531/5747/1029/842/572/5707/8737/356/7532/207/5594/355/330/2810/841/7099/7534/7316/8655/7082/6774/54205/660/8797/3146/23604/5688/10134/329/999/5588/598/836/929/10000/5686/8837/4137/5710/7157/8626/197259/208/6233/5580/6709/5716/6093/1613/7311/7161/8772/331/5599/353376/8717/7159/317/8743/8795/5062/5693/140735/7529/7314/578/5595/148022 78 Human_hepatitis_A_virus_genotype_IB R-HSA-5683057 MAPK family signaling cascades 103/1200 294/10654 7.463219059117474e-28 2.002089634554557e-26 9.563850510539553e-27 2308/818/27161/3725/815/1839/5684/4893/6464/685/1437/3667/71/2309/5604/2065/5747/5707/283455/5567/8844/817/1439/5594/2069/2322/3315/2064/3337/1438/192670/2260/5596/8452/7316/673/1950/8315/4233/983/5597/84078/6714/4609/10818/5566/5037/2261/5688/5159/3558/3717/145957/3084/5686/2335/5063/2534/3690/408/5710/2264/816/192669/4296/2066/5894/5979/6654/9542/6233/2885/10718/6709/3716/5716/8660/7514/7311/5518/1956/5536/5896/4140/1843/3845/3265/26523/5058/369/801/7297/8202/3569/5062/5693/5245/7529/5156/7314/5879/5595/5515 103 Human_hepatitis_A_virus_genotype_IB R-HSA-8848021 Signaling by PTK6 40/1200 54/10654 4.353024396738664e-27 1.119090021994898e-25 5.345819434591341e-26 120892/1017/1839/1019/4893/685/2065/207/2069/55620/1027/3091/2064/1793/7316/1950/5753/6774/867/2908/145957/3084/595/2066/9542/6233/1398/10718/9844/7311/2034/387/1956/9564/3845/3265/63916/5829/7314/5879 40 Human_hepatitis_A_virus_genotype_IB R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 40/1200 54/10654 4.353024396738664e-27 1.119090021994898e-25 5.345819434591341e-26 120892/1017/1839/1019/4893/685/2065/207/2069/55620/1027/3091/2064/1793/7316/1950/5753/6774/867/2908/145957/3084/595/2066/9542/6233/1398/10718/9844/7311/2034/387/1956/9564/3845/3265/63916/5829/7314/5879 40 Human_hepatitis_A_virus_genotype_IB R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 29/1200 30/10654 6.237873819823275e-27 1.5709257742167187e-25 7.504209106554315e-26 7124/1147/81858/7186/56957/6885/8737/55072/7375/330/23118/27005/8517/7316/7128/7132/329/9099/10616/10454/6233/7311/331/8717/1540/3551/7185/7314/257397 29 Human_hepatitis_A_virus_genotype_IB R-HSA-448424 Interleukin-17 signaling 46/1200 72/10654 1.6166840540693806e-26 3.9605689140241022e-25 1.8919377223010298e-25 8454/1147/3725/8945/1326/9252/4790/6885/5606/5604/10392/8767/5594/6500/23118/8517/7316/79155/7335/9261/7867/64127/5598/1432/23291/3656/6195/10454/3654/7189/5609/6233/6196/7311/5518/1386/6197/5599/7334/3551/5608/51231/7314/5595/5515/257397 46 Human_hepatitis_A_virus_genotype_IB R-HSA-73887 Death Receptor Signalling 66/1200 141/10654 1.6368639758122304e-26 3.9605689140241022e-25 1.8919377223010298e-25 7124/1147/4804/57142/81858/7186/56957/4790/6885/5584/10018/7531/572/8737/8767/55072/356/4974/7375/9530/8878/355/330/23118/841/27005/8517/4615/7316/5970/4792/65078/4168/8797/7128/7132/329/84894/9099/843/836/10616/396/8837/4803/10454/3066/3654/7189/6654/4099/6233/7311/387/8772/331/5599/8717/1540/3551/7185/8743/8795/7314/5879/257397 66 Human_hepatitis_A_virus_genotype_IB R-HSA-109581 Apoptosis 75/1200 178/10654 2.4486034127929861e-26 5.810724252666433e-25 2.7757447594414416e-25 23643/4000/596/5684/7186/1612/51765/1499/10018/7531/5747/1029/842/572/5707/8737/356/7532/207/5594/355/2810/841/7099/7534/7316/8655/7082/6774/54205/660/8797/3146/23604/5688/10134/329/999/5588/598/836/929/10000/5686/8837/4137/5710/7157/8626/208/6233/5580/6709/5716/6093/1613/7311/7161/8772/331/5599/353376/8717/7159/317/8743/8795/5062/5693/140735/7529/7314/578/5595/148022 75 Human_hepatitis_A_virus_genotype_IB R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 39/1200 55/10654 2.910971056847009e-25 6.777619404055112e-24 3.237624214169464e-24 1147/596/351/4790/6885/842/10392/8767/10910/330/23118/29108/841/8517/7316/7335/5970/64127/7128/1432/329/598/3656/10454/83737/3654/7189/6233/3326/4210/7311/114548/7334/1540/3551/5608/4791/7314/257397 39 Human_hepatitis_A_virus_genotype_IB R-HSA-2219528 PI3K/AKT Signaling in Cancer 53/1200 101/10654 1.5663413086643966e-24 3.579379953503454e-23 1.7098462628695165e-23 5295/1147/2308/5170/1839/685/5290/3667/2309/5291/2065/842/572/207/2069/4303/1027/7249/2064/6199/2260/2100/1950/4233/1026/6714/2099/10818/2932/2261/5159/3164/10000/145957/3084/2534/5728/2264/2066/208/9542/2885/10718/2475/8660/3932/2931/1956/2549/5156/5879/253260/4193 53 Human_hepatitis_A_virus_genotype_IB R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 61/1200 134/10654 8.782392425570627e-24 1.9704495005734826e-22 9.412707671424977e-23 5295/8454/1147/5170/3725/8945/5684/4893/6464/5290/5335/4790/6885/5291/7321/5707/84433/5594/4214/6500/23118/10892/3708/8517/7316/7335/5970/4792/8915/7322/5688/4067/23291/5588/5686/2534/5710/10454/695/7189/5609/6654/6233/2885/5716/3702/7311/3845/5599/7334/3265/3551/5058/801/5062/5693/997/7314/5879/5595/257397 61 Human_hepatitis_A_virus_genotype_IB R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 45/1200 78/10654 2.663097074979947e-23 5.868324625937954e-22 2.8032600789262594e-22 1147/351/7186/4790/7321/8737/9140/29110/57506/4214/9636/54476/841/7706/8517/84166/9474/7316/5970/4792/4793/3146/23586/7322/7128/1387/843/2033/64135/83737/3661/7189/51191/6233/10010/7311/84282/79671/7187/8772/9641/1540/3551/4791/7314 45 Human_hepatitis_A_virus_genotype_IB R-HSA-75893 TNF signaling 32/1200 43/10654 5.173273273972109e-22 1.119968284224839e-20 5.350014835502088e-21 7124/1147/81858/7186/56957/6885/8737/55072/7375/9530/330/23118/841/27005/8517/7316/7128/7132/329/9099/10616/10454/6233/7311/8772/331/8717/1540/3551/7185/7314/257397 32 Human_hepatitis_A_virus_genotype_IB R-HSA-9607240 FLT3 Signaling 88/1200 267/10654 7.899724264079739e-22 1.6807344382542064e-20 8.028757872748919e-21 5295/818/5170/815/1839/5684/4893/6464/685/5290/1437/3667/71/5291/5604/2065/5747/5707/283455/8844/817/1439/5594/2069/2322/2064/1438/2260/8452/7316/673/1950/8315/5289/4233/3055/84078/6714/10818/5037/2261/5688/5159/3558/3717/145957/3084/5686/2335/2534/3690/408/5710/2264/816/4296/2066/5894/5979/208/6654/9542/6233/2885/10718/6709/3716/5716/8660/7311/5518/1956/5536/4140/1843/3845/2549/3265/369/801/30849/5693/5245/7529/5156/7314/5595/5515 88 Human_hepatitis_A_virus_genotype_IB R-HSA-983169 Class I MHC mediated antigen processing & presentation 108/1200 371/10654 9.814652623274556e-22 2.0527595486645426e-20 9.805897357776541e-21 8454/23643/1147/8773/26224/8945/5684/6737/8065/64410/127544/9666/55070/84708/54850/7319/7321/5707/10273/9817/10193/821/6500/811/10533/144699/26259/51130/10333/7099/8517/4615/8452/54778/7316/7317/7335/7096/84861/11059/4734/84078/7337/26272/222235/7322/23327/55905/5688/10134/55336/26270/6502/23291/10616/929/3309/5686/55521/114609/9903/55294/26190/55008/79654/5710/135892/7428/22954/8453/83737/9040/695/90933/10075/79176/80176/8139/51191/126433/6233/9870/26267/5716/3685/25793/51343/7311/26091/6047/51666/90293/54461/29882/127247/7334/7097/4591/3551/26268/115290/90678/51725/140459/5693/997/51676/7314 108 Human_hepatitis_A_virus_genotype_IB R-HSA-5621481 C-type lectin receptors (CLRs) 60/1200 142/10654 2.2934418861143066e-21 4.7168454791084236e-20 2.2532060635508974e-20 8454/1147/5170/8945/5684/9252/4893/4790/6885/7321/5707/5567/84433/4582/6500/3384/23118/10892/29108/3708/841/8517/7316/9020/7335/5970/4792/8915/6714/5566/7322/5688/1387/4067/23291/5686/5063/2534/2033/5710/10454/9040/5894/7189/6233/5580/5716/7311/3845/7334/3265/3551/5058/801/5062/5693/997/4791/7314/257397 60 Human_hepatitis_A_virus_genotype_IB R-HSA-9020702 Interleukin-1 signaling 49/1200 103/10654 2.271777487098901e-20 4.595694129639416e-19 2.195332860699542e-19 8454/1147/8945/1326/5684/351/4790/6885/5604/4215/11213/5707/10392/8767/8878/6500/23118/246330/8517/4615/7316/79155/7335/5970/4792/4793/3146/64127/5688/23291/5686/3656/57162/5710/10454/3654/7189/6233/5716/51135/7311/7334/3551/5608/57161/5693/4791/7314/257397 49 Human_hepatitis_A_virus_genotype_IB R-HSA-8863795 Downregulation of ERBB2 signaling 25/1200 29/10654 2.372018586138836e-20 4.721082153702134e-19 2.2552298951404895e-19 1839/8065/685/2065/10273/207/10193/2069/2064/7316/1950/10000/145957/3320/3084/2066/208/4145/9542/6233/10718/7311/1956/11140/7314 25 Human_hepatitis_A_virus_genotype_IB R-HSA-168638 NOD1/2 Signaling Pathway 28/1200 36/10654 2.594296580742134e-20 5.081526953390148e-19 2.427412005372757e-19 1147/6885/842/10392/8767/330/23118/841/8517/7316/7335/64127/7128/1432/329/3656/10454/83737/3654/7189/6233/7311/7334/1540/3551/5608/7314/257397 28 Human_hepatitis_A_virus_genotype_IB R-HSA-3371556 Cellular response to heat stress 45/1200 89/10654 3.6689032951501503e-20 7.074104165961384e-19 3.3792530350067173e-19 818/3303/6118/815/81929/7531/1915/817/5594/9530/3308/10013/545/3337/3313/10808/3305/9261/9532/7415/6119/2932/1387/3310/3309/3320/2033/7266/6767/816/9531/22824/3326/2475/3306/23411/6117/3304/3312/3297/57521/2288/10728/51182/5595 45 Human_hepatitis_A_virus_genotype_IB R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 44/1200 86/10654 5.266268953277999e-20 9.997809058992387e-19 4.775887633741991e-19 5295/26999/25/1072/3984/5290/5335/71/5291/5747/10006/4627/10458/4771/5594/2268/3708/1793/3055/10152/6714/8936/10163/4067/10810/3320/55845/2534/695/8976/2885/7525/1398/3326/5580/23191/9844/5581/5058/3071/63916/10787/5879/5595 44 Human_hepatitis_A_virus_genotype_IB R-HSA-202424 Downstream TCR signaling 47/1200 98/10654 8.958629544666724e-20 1.6749922512301116e-18 8.001327822987823e-19 5295/8454/1147/5170/8945/5684/5290/4790/6885/5291/7321/5707/8767/84433/6500/3123/23118/10892/8517/3126/3115/7316/3122/920/7335/5970/4792/8915/7322/5688/23291/5588/5686/5728/5710/7189/6233/5716/7311/3932/3127/3125/7334/3551/5693/997/7314 47 Human_hepatitis_A_virus_genotype_IB R-HSA-5213460 RIPK1-mediated regulated necrosis 20/1200 20/10654 9.375232664532196e-20 1.7013289864754016e-18 8.127136675136269e-19 11035/7186/8737/356/355/330/841/7316/8797/329/8837/197259/6233/7311/8772/331/8717/8743/8795/7314 20 Human_hepatitis_A_virus_genotype_IB R-HSA-5218859 Regulated Necrosis 20/1200 20/10654 9.375232664532196e-20 1.7013289864754016e-18 8.127136675136269e-19 11035/7186/8737/356/355/330/841/7316/8797/329/8837/197259/6233/7311/8772/331/8717/8743/8795/7314 20 Human_hepatitis_A_virus_genotype_IB R-HSA-5684996 MAPK1/MAPK3 signaling 82/1200 255/10654 1.1942380869432867e-19 2.1357823178087185e-18 1.0202491665724494e-18 818/815/1839/5684/4893/6464/685/1437/3667/71/5604/2065/5747/5707/283455/8844/817/1439/5594/2069/2322/2064/1438/2260/8452/7316/673/1950/8315/4233/983/84078/6714/10818/5037/2261/5688/5159/3558/3717/145957/3084/5686/2335/2534/3690/408/5710/2264/816/4296/2066/5894/5979/6654/9542/6233/2885/10718/6709/3716/5716/8660/7311/5518/1956/5536/4140/1843/3845/3265/369/801/7297/3569/5693/5245/7529/5156/7314/5595/5515 82 Human_hepatitis_A_virus_genotype_IB R-HSA-202403 TCR signaling 52/1200 119/10654 1.812461043549539e-19 3.1951098967716158e-18 1.5262829840417169e-18 5295/8454/1147/5170/8945/5684/5290/5335/4790/6885/5291/7321/5707/8767/84433/6500/3123/23118/10892/8517/3126/3115/7316/3122/920/7335/5970/4792/8915/7322/5688/23291/5588/5686/5063/5728/5710/7189/6233/5716/3702/7311/3932/3127/3125/7334/3551/5058/5062/5693/997/7314 52 Human_hepatitis_A_virus_genotype_IB R-HSA-1250196 SHC1 events in ERBB2 signaling 21/1200 22/10654 2.0464670635723346e-19 3.556817403448255e-18 1.6990682810978612e-18 1839/4893/6464/685/2065/5578/2069/2064/1950/145957/3084/2066/6654/9542/2885/10718/5580/1956/5581/3845/3265 21 Human_hepatitis_A_virus_genotype_IB R-HSA-450302 activated TAK1 mediates p38 MAPK activation 22/1200 24/10654 2.5446941633652906e-19 4.3613230522121784e-18 2.083375338427723e-18 6885/5606/10392/8767/23118/8517/7316/7335/9261/7867/64127/1432/3656/10454/3654/7189/6233/7311/7334/5608/7314/257397 22 Human_hepatitis_A_virus_genotype_IB R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 26/1200 33/10654 3.3650692768947944e-19 5.611480388767806e-18 2.6805672760470624e-18 1147/351/4790/6885/10392/8767/23118/8517/7316/7335/5970/4792/4793/3146/64127/3656/10454/3654/7189/6233/7311/7334/3551/4791/7314/257397 26 Human_hepatitis_A_virus_genotype_IB R-HSA-5357905 Regulation of TNFR1 signaling 26/1200 33/10654 3.3650692768947944e-19 5.611480388767806e-18 2.6805672760470624e-18 7124/1147/81858/7186/56957/8737/55072/7375/330/841/27005/8517/7316/7128/7132/329/9099/10616/6233/7311/331/8717/1540/3551/7185/7314 26 Human_hepatitis_A_virus_genotype_IB R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 19/1200 19/10654 8.442472429068591e-19 1.3707909180882422e-17 6.548178061327438e-18 5295/4893/6464/5290/5335/7316/1950/867/3320/6654/6233/2885/7311/1956/3845/2549/3265/11140/7314 19 Human_hepatitis_A_virus_genotype_IB R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 19/1200 19/10654 8.442472429068591e-19 1.3707909180882422e-17 6.548178061327438e-18 5295/4893/6464/5290/5335/7316/1950/867/3320/6654/6233/2885/7311/1956/3845/2549/3265/11140/7314 19 Human_hepatitis_A_virus_genotype_IB R-HSA-3700989 Transcriptional Regulation by TP53 101/1200 365/10654 1.2348189934366196e-18 1.9789177115594657e-17 9.453159758366465e-18 1017/6118/2176/5170/27161/5563/3725/5434/8621/5883/7531/1029/1459/6446/8445/7532/207/22974/9212/1027/4869/51422/7249/355/2810/1460/545/53632/192670/7534/332/639/7316/1457/983/1026/54205/6790/641/8797/4194/112858/6119/3364/1432/5571/10524/1387/56950/9099/843/10000/6794/2033/995/1874/10128/5728/6009/1111/192669/3066/7157/1107/8626/208/6233/2475/672/1025/604/7311/7161/5562/5518/1386/55835/10419/8851/6117/7159/57472/6829/26523/5564/317/5565/1020/5608/5810/10397/1022/8795/665/57521/7248/7529/7314/253260/4193/5515 101 Human_hepatitis_A_virus_genotype_IB R-HSA-5673001 RAF/MAP kinase cascade 79/1200 249/10654 1.4150535102571751e-18 2.2308512887440552e-17 1.0656629887372438e-17 818/815/1839/5684/4893/6464/685/1437/3667/71/5604/2065/5747/5707/283455/8844/817/1439/5594/2069/2322/2064/1438/2260/8452/7316/673/1950/8315/4233/84078/6714/10818/5037/2261/5688/5159/3558/3717/145957/3084/5686/2335/2534/3690/408/5710/2264/816/4296/2066/5894/5979/6654/9542/6233/2885/10718/6709/3716/5716/8660/7311/5518/1956/5536/4140/1843/3845/3265/369/801/5693/5245/7529/5156/7314/5595/5515 79 Human_hepatitis_A_virus_genotype_IB R-HSA-8951664 Neddylation 76/1200 234/10654 1.4281787018701812e-18 2.2308512887440552e-17 1.0656629887372438e-17 8454/26224/54165/8945/5684/8065/64410/149951/23038/64344/54850/55884/7321/5707/4738/9817/6500/3091/144699/26259/51130/332/8452/8450/9306/7316/84861/84078/26272/222235/10980/7322/5688/55336/26270/6502/7347/23291/90864/55832/1642/5686/9903/55294/26190/5710/10987/7428/8453/9040/79176/80176/8139/126433/6233/26267/5716/25793/7311/51666/2034/90293/8533/54461/8835/127247/26268/115290/51725/140459/5693/51676/50813/7314/51138/8451 76 Human_hepatitis_A_virus_genotype_IB R-HSA-1643713 Signaling by EGFR in Cancer 22/1200 25/10654 1.895900008466566e-18 2.9244257630596785e-17 1.396978953606943e-17 5295/1839/4893/6464/685/5290/5335/2069/7316/1950/867/3320/6654/6233/2885/7311/1956/3845/2549/3265/11140/7314 22 Human_hepatitis_A_virus_genotype_IB R-HSA-5633007 Regulation of TP53 Activity 60/1200 160/10654 2.699226179346352e-18 4.112154451004195e-17 1.9643491363664158e-17 1017/6118/5170/5563/5883/1029/1459/6446/8445/207/22974/9212/51422/1460/545/53632/639/7316/1457/983/6790/641/4194/112858/6119/3364/1432/5571/10524/56950/9099/10000/6794/2033/1111/3066/7157/1107/8626/208/6233/2475/672/7311/7161/5562/5518/10419/8851/6117/7159/5564/5565/1020/5608/5810/7314/253260/4193/5515 60 Human_hepatitis_A_virus_genotype_IB R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 90/1200 309/10654 2.849420839240618e-18 4.288030872710881e-17 2.0483641463090448e-17 8454/26224/8945/5684/6737/8065/64410/127544/9666/55070/84708/54850/7319/7321/5707/10273/9817/10193/6500/10533/144699/26259/51130/8452/54778/7316/7317/7335/84861/11059/4734/84078/7337/26272/222235/7322/23327/55905/5688/55336/26270/6502/23291/10616/5686/55521/9903/55294/26190/55008/79654/5710/135892/7428/22954/8453/83737/9040/90933/10075/79176/80176/8139/51191/126433/6233/9870/26267/5716/25793/51343/7311/26091/6047/51666/90293/54461/29882/127247/7334/4591/26268/115290/90678/51725/140459/5693/997/51676/7314 90 Human_hepatitis_A_virus_genotype_IB R-HSA-5675482 Regulation of necroptotic cell death 18/1200 18/10654 7.596796679828568e-18 1.1294514581817412e-16 5.395315333803421e-17 7186/8737/356/355/330/841/7316/8797/329/8837/6233/7311/8772/331/8717/8743/8795/7314 18 Human_hepatitis_A_virus_genotype_IB R-HSA-438064 Post NMDA receptor activation events 40/1200 81/10654 1.3553344731608544e-17 1.991050880810112e-16 9.511119109900733e-17 818/5170/5563/815/4893/79861/5567/817/10382/5594/51422/7277/53632/10645/6714/5566/84254/5571/27330/7846/347733/3084/6195/4137/816/2066/5613/5577/6196/5562/10383/6197/3845/3265/5564/801/5565/814/5879/5595 40 Human_hepatitis_A_virus_genotype_IB R-HSA-195258 RHO GTPase Effectors 92/1200 327/10654 1.4396163835415422e-17 2.0899842556356036e-16 9.983717334777258e-17 26999/5170/11130/25/81929/5590/1072/3984/79861/54908/71/5579/1499/25936/7531/5747/80776/1783/10006/4627/2316/7532/10458/4771/5578/10382/9212/5594/3985/1027/1080/2810/7277/79980/6232/7534/332/1780/5048/1781/8655/5289/5585/10152/6279/6714/8936/1432/10163/7846/999/10810/347733/22919/55845/5063/9475/995/3895/79003/11243/51143/695/8976/2885/5580/23191/7514/6093/57120/367/5518/10383/54820/5347/387/23332/5058/801/3071/9793/10726/30849/5586/5062/140735/7529/10787/5879/5595/5515/1778 92 Human_hepatitis_A_virus_genotype_IB R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 25/1200 34/10654 2.987467002440865e-17 4.2866677686186365e-16 2.0477130004490626e-16 7321/9140/29110/57506/9636/54476/7706/84166/9474/7316/23586/7322/7128/64135/83737/3661/51191/6233/7311/84282/79671/7187/9641/1540/7314 25 Human_hepatitis_A_virus_genotype_IB R-HSA-937041 IKK complex recruitment mediated by RIP1 21/1200 25/10654 8.413275606349751e-17 1.1933312756592635e-15 5.700465020636249e-16 23643/1147/11035/7321/8737/330/7099/8517/7316/7335/7322/329/929/7189/6233/7311/353376/7334/3551/7314/148022 21 Human_hepatitis_A_virus_genotype_IB R-HSA-5689896 Ovarian tumor domain proteases 26/1200 38/10654 1.215879507744793e-16 1.704994673360312e-15 8.144647420300048e-16 56957/7321/8737/10392/8767/57506/7706/8517/7316/79155/983/2099/7415/23586/64127/7128/64135/5728/7157/7189/6233/7311/84282/7187/387/7314 26 Human_hepatitis_A_virus_genotype_IB R-HSA-166520 Signaling by NTRKs 44/1200 101/10654 1.3083015210111985e-16 1.793826752142021e-15 8.568992418318962e-16 5295/9252/4893/6464/5290/3667/5335/4915/5291/5604/5594/673/6774/9261/6714/10818/7867/5598/1432/4914/2534/6195/4803/6654/2885/1398/8660/6196/5518/1213/387/8851/6197/3845/2549/3265/1020/51231/4916/7529/5879/5595/5515/5607 44 Human_hepatitis_A_virus_genotype_IB R-HSA-5607764 CLEC7A (Dectin-1) signaling 44/1200 101/10654 1.3083015210111985e-16 1.793826752142021e-15 8.568992418318962e-16 8454/1147/5170/8945/5684/4790/6885/7321/5707/84433/6500/23118/10892/29108/3708/841/8517/7316/9020/7335/5970/4792/8915/6714/7322/5688/23291/5686/5710/10454/9040/7189/6233/5580/5716/7311/7334/3551/801/5693/997/4791/7314/257397 44 Human_hepatitis_A_virus_genotype_IB R-HSA-446652 Interleukin-1 family signaling 53/1200 140/10654 1.6302040063356707e-16 2.210628289910129e-15 1.0560025951971954e-15 8454/1147/8945/1326/5684/351/4790/6885/5604/4215/11213/5707/10392/8767/29110/8878/6500/23118/246330/8517/4615/7316/79155/6774/7335/5970/4792/4793/3146/64127/5688/23291/5686/84867/3656/57162/5710/10454/3654/7189/6233/5716/51135/7311/5599/7334/3551/5608/57161/5693/4791/7314/257397 53 Human_hepatitis_A_virus_genotype_IB R-HSA-5688426 Deubiquitination 84/1200 297/10654 2.8036380771751556e-16 3.760531942645806e-15 1.7963813766797333e-15 23032/5684/7186/56957/6885/51651/2648/7321/5707/8737/10392/8767/4738/7375/2625/9817/57506/4303/10445/91833/1080/330/3091/11274/4287/27005/7706/8517/7316/79155/7417/4792/9738/8658/983/8678/2099/9100/4609/7415/4194/23586/64127/7128/4798/5688/9097/329/7046/6502/7347/9099/5686/2033/408/64135/5728/5710/10454/7157/10869/8975/4087/7189/6233/5716/672/7048/9804/7311/84282/367/114548/7187/387/23770/8607/7345/3054/1540/5693/5886/7314/4193 84 Human_hepatitis_A_virus_genotype_IB R-HSA-187037 Signaling by NTRK1 (TRKA) 38/1200 80/10654 4.635812420746883e-16 6.1511747604318864e-15 2.9383757279210575e-15 5295/9252/4893/6464/5290/3667/5335/4915/5291/5604/5594/673/6774/9261/6714/10818/7867/5598/1432/4914/6195/4803/6654/2885/1398/8660/6196/5518/1213/387/6197/3845/3265/51231/7529/5595/5515/5607 38 Human_hepatitis_A_virus_genotype_IB R-HSA-193639 p75NTR signals via NF-kB 16/1200 16/10654 6.137241334174824e-16 7.807583305537868e-15 3.729631196025938e-15 4804/4790/5584/8767/8878/4615/7316/5970/4792/4803/3654/7189/6233/7311/3551/7314 16 Human_hepatitis_A_virus_genotype_IB R-HSA-1963640 GRB2 events in ERBB2 signaling 16/1200 16/10654 6.137241334174824e-16 7.807583305537868e-15 3.729631196025938e-15 1839/4893/685/2069/2064/1950/145957/3084/2066/6654/9542/2885/10718/1956/3845/3265 16 Human_hepatitis_A_virus_genotype_IB R-HSA-1963642 PI3K events in ERBB2 signaling 16/1200 16/10654 6.137241334174824e-16 7.807583305537868e-15 3.729631196025938e-15 5295/1839/685/5290/2065/2069/2064/1950/145957/3084/2066/9542/2885/10718/1956/2549 16 Human_hepatitis_A_virus_genotype_IB R-HSA-399954 Sema3A PAK dependent Axon repulsion 16/1200 16/10654 6.137241334174824e-16 7.807583305537868e-15 3.729631196025938e-15 1072/3984/5361/10371/8829/55558/3320/5063/2534/91584/3326/5362/5058/5062/5879/2242 16 Human_hepatitis_A_virus_genotype_IB R-HSA-5260271 Diseases of Immune System 20/1200 24/10654 6.373498436608228e-16 7.944340475529853e-15 3.794959196704528e-15 23643/1147/4790/10333/7099/8517/4615/7098/5970/4792/7096/929/114609/695/51135/7187/7097/3551/4791/148022 20 Human_hepatitis_A_virus_genotype_IB R-HSA-5602358 Diseases associated with the TLR signaling cascade 20/1200 24/10654 6.373498436608228e-16 7.944340475529853e-15 3.794959196704528e-15 23643/1147/4790/10333/7099/8517/4615/7098/5970/4792/7096/929/114609/695/51135/7187/7097/3551/4791/148022 20 Human_hepatitis_A_virus_genotype_IB R-HSA-9009391 Extra-nuclear estrogen signaling 37/1200 77/10654 7.039850212047761e-16 8.687175161666937e-15 4.149806440786048e-15 5295/5170/596/5590/1839/4893/6464/685/857/5290/2309/5747/207/5594/2069/1027/3315/2100/4313/1950/6714/2099/10000/3320/4846/595/2771/208/7514/1956/3845/858/3265/801/8877/3480/5595 37 Human_hepatitis_A_virus_genotype_IB R-HSA-199418 Negative regulation of the PI3K/AKT network 45/1200 110/10654 1.0651638586840213e-15 1.3013982194218636e-14 6.21669370362743e-15 5295/1839/685/5290/3667/5291/2065/207/5594/2069/2064/2260/4615/2100/1950/4233/6714/2099/10818/2261/5159/10000/145957/3084/2534/5728/2264/3630/2066/3654/7189/208/9542/2885/10718/51135/8660/3932/5518/1956/2549/5156/5879/5595/5515 45 Human_hepatitis_A_virus_genotype_IB R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 18/1200 20/10654 1.1554940095773108e-15 1.3979211841356878e-14 6.67777755792873e-15 1147/11035/7321/8737/330/8517/7098/7316/7335/7322/329/7189/6233/7311/7334/3551/7314/148022 18 Human_hepatitis_A_virus_genotype_IB R-HSA-109606 Intrinsic Pathway for Apoptosis 30/1200 53/10654 1.1986565137871659e-15 1.4360603281683133e-14 6.8599657406317104e-15 596/10018/7531/1029/842/572/7532/207/5594/2810/841/7534/8655/6774/54205/598/836/10000/7157/8626/208/7161/331/5599/7159/317/140735/7529/578/5595 30 Human_hepatitis_A_virus_genotype_IB R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 21/1200 27/10654 1.5742884748384847e-15 1.8679538249525868e-14 8.923092569934731e-15 23643/7186/1612/842/8737/356/355/841/7099/8797/23604/836/929/8837/1613/8772/353376/8717/8743/8795/148022 21 Human_hepatitis_A_virus_genotype_IB R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 28/1200 47/10654 1.7341806370496446e-15 1.9814619501104274e-14 9.46531341859455e-15 818/815/4893/71/5604/283455/8844/817/5594/673/8315/6714/5037/3717/2335/3690/408/816/4296/5894/4140/3845/3265/369/801/5245/7529/5595 28 Human_hepatitis_A_virus_genotype_IB R-HSA-6802949 Signaling by RAS mutants 28/1200 47/10654 1.7341806370496446e-15 1.9814619501104274e-14 9.46531341859455e-15 818/815/4893/71/5604/283455/8844/817/5594/673/8315/6714/5037/3717/2335/3690/408/816/4296/5894/4140/3845/3265/369/801/5245/7529/5595 28 Human_hepatitis_A_virus_genotype_IB R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 28/1200 47/10654 1.7341806370496446e-15 1.9814619501104274e-14 9.46531341859455e-15 818/815/4893/71/5604/283455/8844/817/5594/673/8315/6714/5037/3717/2335/3690/408/816/4296/5894/4140/3845/3265/369/801/5245/7529/5595 28 Human_hepatitis_A_virus_genotype_IB R-HSA-9649948 Signaling downstream of RAS mutants 28/1200 47/10654 1.7341806370496446e-15 1.9814619501104274e-14 9.46531341859455e-15 818/815/4893/71/5604/283455/8844/817/5594/673/8315/6714/5037/3717/2335/3690/408/816/4296/5894/4140/3845/3265/369/801/5245/7529/5595 28 Human_hepatitis_A_virus_genotype_IB R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 20/1200 25/10654 2.850218194050092e-15 3.226760781153957e-14 1.5414024033491562e-14 1147/2308/5170/2309/842/572/207/4303/1027/7249/6199/1026/2932/3164/10000/208/2475/2931/253260/4193 20 Human_hepatitis_A_virus_genotype_IB R-HSA-1236394 Signaling by ERBB4 31/1200 58/10654 3.539200061989557e-15 3.9703389786319214e-14 1.8966048179082793e-14 5295/1839/4893/6464/685/5290/5241/2065/2069/23118/7316/1950/11059/4734/10413/6714/2099/145957/3084/2066/83737/6654/9542/6233/2885/10718/7311/1956/3845/3265/7314 31 Human_hepatitis_A_virus_genotype_IB R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 19/1200 23/10654 4.786868359861458e-15 5.321617618080215e-14 2.5421017368633632e-14 6885/10392/8767/23118/8517/7316/7335/64127/3656/10454/3654/7189/5609/6233/7311/5599/7334/7314/257397 19 Human_hepatitis_A_virus_genotype_IB R-HSA-442755 Activation of NMDA receptors and postsynaptic events 40/1200 93/10654 5.466479491716298e-15 5.964389105336373e-14 2.8491494489365934e-14 818/5170/5563/815/4893/79861/5567/817/10382/5594/51422/7277/53632/10645/6714/5566/84254/5571/27330/7846/347733/3084/6195/4137/816/2066/5613/5577/6196/5562/10383/6197/3845/3265/5564/801/5565/814/5879/5595 40 Human_hepatitis_A_virus_genotype_IB R-HSA-5637810 Constitutive Signaling by EGFRvIII 15/1200 15/10654 5.510051523568448e-15 5.964389105336373e-14 2.8491494489365934e-14 5295/4893/6464/5290/5335/1950/867/3320/6654/2885/1956/3845/2549/3265/11140 15 Human_hepatitis_A_virus_genotype_IB R-HSA-5637812 Signaling by EGFRvIII in Cancer 15/1200 15/10654 5.510051523568448e-15 5.964389105336373e-14 2.8491494489365934e-14 5295/4893/6464/5290/5335/1950/867/3320/6654/2885/1956/3845/2549/3265/11140 15 Human_hepatitis_A_virus_genotype_IB R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 18/1200 21/10654 7.23728995046298e-15 7.765926781627233e-14 3.7097321485210695e-14 1147/11035/4790/8737/29110/23220/147945/8517/4615/7098/5970/4792/4793/3661/81030/3551/4791/148022 18 Human_hepatitis_A_virus_genotype_IB R-HSA-2871837 FCERI mediated NF-kB activation 37/1200 82/10654 8.945984139491542e-15 9.516676231148761e-14 4.546053646202599e-14 8454/1147/5170/8945/5684/4790/6885/7321/5707/84433/6500/23118/10892/8517/7316/7335/5970/4792/8915/7322/5688/4067/23291/5588/5686/5710/10454/7189/6233/5716/7311/7334/3551/5693/997/7314/257397 37 Human_hepatitis_A_virus_genotype_IB R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 16/1200 17/10654 9.34039900813663e-15 9.851326817128719e-14 4.705914030190295e-14 23643/7186/8737/356/355/841/7099/8797/929/8837/8772/353376/8717/8743/8795/148022 16 Human_hepatitis_A_virus_genotype_IB R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 42/1200 103/10654 1.1091134916819213e-14 1.159869532826687e-13 5.54062047584189e-14 5295/1839/685/5290/3667/5291/2065/207/5594/2069/2064/2260/4615/2100/1950/4233/6714/2099/10818/2261/5159/145957/3084/2534/2264/3630/2066/3654/7189/9542/2885/10718/51135/8660/3932/5518/1956/2549/5156/5879/5595/5515 42 Human_hepatitis_A_virus_genotype_IB R-HSA-3371571 HSF1-dependent transactivation 19/1200 24/10654 2.0555038721423626e-14 2.131505695986282e-13 1.018206252454421e-13 818/3303/815/817/3337/3305/1387/3320/2033/816/3326/2475/3306/3304/3312/3297/57521/2288/10728 19 Human_hepatitis_A_virus_genotype_IB R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 31/1200 61/10654 2.2379832642685308e-14 2.3013927900894725e-13 1.0993601999915589e-13 26999/25/1072/3984/71/5747/10006/4627/10458/4771/5594/1793/10152/8936/10163/10810/3320/55845/695/8976/2885/1398/3326/23191/9844/5058/3071/63916/10787/5879/5595 31 Human_hepatitis_A_virus_genotype_IB R-HSA-69231 Cyclin D associated events in G1 26/1200 44/10654 2.3565680330227773e-14 2.383610617008285e-13 1.1386351151792536e-13 8454/25/894/1019/1029/1027/6500/5925/7316/5753/1026/6714/4067/3717/6502/1021/1874/595/6233/1030/7311/5518/1163/1022/7314/5515 26 Human_hepatitis_A_virus_genotype_IB R-HSA-69236 G1 Phase 26/1200 44/10654 2.3565680330227773e-14 2.383610617008285e-13 1.1386351151792536e-13 8454/25/894/1019/1029/1027/6500/5925/7316/5753/1026/6714/4067/3717/6502/1021/1874/595/6233/1030/7311/5518/1163/1022/7314/5515 26 Human_hepatitis_A_virus_genotype_IB R-HSA-5673000 RAF activation 22/1200 32/10654 2.4292054018238198e-14 2.437105256789101e-13 1.1641891527782106e-13 818/815/4893/5604/8844/817/673/8315/6714/3717/816/4296/5894/5518/4140/3845/3265/369/801/5245/7529/5515 22 Human_hepatitis_A_virus_genotype_IB R-HSA-8939211 ESR-mediated signaling 66/1200 223/10654 4.562023277261488e-14 4.53994897108119e-13 2.1687037650818616e-13 5295/5170/27161/3725/596/5434/5590/1839/4893/6464/685/857/5290/7090/5241/2309/5747/8204/207/2625/5594/2069/1027/3315/5481/192670/5885/2100/4313/1950/6667/2289/6714/2099/4609/10524/1387/10000/3320/2033/8243/4846/9126/595/192669/2066/2771/208/3326/7514/1025/1386/1956/5536/3169/3845/858/3265/26523/801/8202/8877/3480/2288/10728/5595 66 Human_hepatitis_A_virus_genotype_IB R-HSA-1250347 SHC1 events in ERBB4 signaling 14/1200 14/10654 4.943250270722439e-14 4.879976667257192e-13 2.3311327592459504e-13 1839/4893/6464/685/2069/145957/3084/2066/6654/9542/2885/10718/3845/3265 14 Human_hepatitis_A_virus_genotype_IB R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 31/1200 63/10654 7.035395739247462e-14 6.890220906532832e-13 3.2914132113438417e-13 1147/11035/5434/6737/4790/1499/8737/29110/81844/23220/147945/8517/6778/4615/7098/5591/7316/5970/4792/4793/1387/2033/22954/3661/6233/7311/81030/3551/4791/7314/148022 31 Human_hepatitis_A_virus_genotype_IB R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 15/1200 16/10654 7.895496237583228e-14 7.61175184154508e-13 3.636083793623855e-13 8454/1147/8945/1326/4790/5604/6500/8517/7316/79155/23291/6233/7311/3551/7314 15 Human_hepatitis_A_virus_genotype_IB R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 15/1200 16/10654 7.895496237583228e-14 7.61175184154508e-13 3.636083793623855e-13 23643/6885/23118/7099/7316/929/3656/10454/7189/6233/7311/353376/7314/148022/257397 15 Human_hepatitis_A_virus_genotype_IB R-HSA-6802957 Oncogenic MAPK signaling 33/1200 71/10654 8.829222788129146e-14 8.445938698101834e-13 4.034569368708545e-13 4000/27044/818/815/4893/71/5604/10018/10142/283455/8844/817/5594/10533/673/8315/6714/5037/3717/2335/3690/408/816/4296/5894/4140/3845/3265/369/801/5245/7529/5595 33 Human_hepatitis_A_virus_genotype_IB R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 38/1200 92/10654 1.266977697208428e-13 1.2026542141193847e-12 5.745000084507851e-13 1017/6118/5563/5883/1459/8445/22974/9212/51422/1460/545/53632/7316/1457/6790/641/4194/112858/6119/3364/1432/5571/10524/6794/1111/7157/6233/672/7311/5562/8851/6117/5564/5565/1020/5810/7314/4193 38 Human_hepatitis_A_virus_genotype_IB R-HSA-5621575 CD209 (DC-SIGN) signaling 17/1200 21/10654 2.6232184662491957e-013 2.4710317460698533e-12 1.180395613579389e-12 9252/4893/4790/5567/3384/5970/5566/1387/4067/5063/2534/2033/5894/3845/3265/5058/5062 17 Human_hepatitis_A_virus_genotype_IB R-HSA-209543 p75NTR recruits signalling complexes 13/1200 13/10654 4.4314343833831007e-13 4.050659280810924e-12 1.934973298007436e-12 4804/5584/8767/8878/4615/7316/4803/3654/7189/6233/7311/3551/7314 13 Human_hepatitis_A_virus_genotype_IB R-HSA-209560 NF-kB is activated and signals survival 13/1200 13/10654 4.4314343833831007e-13 4.050659280810924e-12 1.934973298007436e-12 4804/4790/8878/7316/5970/4792/4803/3654/7189/6233/7311/3551/7314 13 Human_hepatitis_A_virus_genotype_IB R-HSA-5357786 TNFR1-induced proapoptotic signaling 13/1200 13/10654 4.4314343833831007e-13 4.050659280810924e-12 1.934973298007436e-12 7124/7186/56957/8737/7375/841/27005/7128/7132/9099/8772/8717/1540 13 Human_hepatitis_A_virus_genotype_IB R-HSA-8847993 ERBB2 Activates PTK6 Signaling 13/1200 13/10654 4.4314343833831007e-13 4.050659280810924e-12 1.934973298007436e-12 1839/685/2065/2069/2064/1950/5753/145957/3084/2066/9542/10718/1956 13 Human_hepatitis_A_virus_genotype_IB R-HSA-933542 TRAF6 mediated NF-kB activation 18/1200 24/10654 5.247629634131402e-13 4.761452182733934e-12 2.274514392502775e-12 1147/351/7186/4790/57506/4214/7706/8517/5970/4792/4793/3146/23586/64135/7189/84282/3551/4791 18 Human_hepatitis_A_virus_genotype_IB R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 15/1200 17/10654 6.010641876335558e-13 5.413965018538744e-12 2.586215482710651e-12 23643/6885/23118/7099/7316/929/3656/10454/7189/6233/7311/353376/7314/148022/257397 15 Human_hepatitis_A_virus_genotype_IB R-HSA-937039 IRAK1 recruits IKK complex 14/1200 15/10654 6.643468192784071e-13 5.897870323665859e-12 2.8173738644142974e-12 1147/246330/8517/7316/7335/57162/3654/7189/6233/7311/7334/3551/57161/7314 14 Human_hepatitis_A_virus_genotype_IB R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 14/1200 15/10654 6.643468192784071e-13 5.897870323665859e-12 2.8173738644142974e-12 1147/246330/8517/7316/7335/57162/3654/7189/6233/7311/7334/3551/57161/7314 14 Human_hepatitis_A_virus_genotype_IB R-HSA-453279 Mitotic G1-G1/S phases 49/1200 149/10654 1.2077259271184009e-12 1.0645241386172191e-11 5.085161798393267e-12 8454/1017/4172/6118/25/894/1019/5684/1029/5707/207/1027/6500/5925/4149/7316/4174/5753/983/1026/6714/4171/4609/6119/5688/4067/3717/6502/10000/5686/1021/1874/595/5710/208/6233/7298/5716/1030/7311/5518/6117/7465/1163/1022/5693/7314/5515/6241 49 Human_hepatitis_A_virus_genotype_IB R-HSA-9614085 FOXO-mediated transcription 30/1200 65/10654 1.4993377768753651e-12 1.3121863947973054e-11 6.2682281078776e-12 2308/857/2309/65018/10018/356/7532/207/4303/1027/2810/4287/6720/7534/847/1026/1387/2908/10000/6794/2033/3630/3066/4087/91584/208/604/23411/25942/7529 30 Human_hepatitis_A_virus_genotype_IB R-HSA-983705 Signaling by the B Cell Receptor (BCR) 41/1200 112/10654 1.6419296531536623e-12 1.4268599943602951e-11 6.8160163511197245e-012 5295/8454/1147/8945/5684/4893/4790/6885/5579/5966/5707/640/84433/6500/10892/3708/8517/7316/5970/4792/4793/8915/5688/4067/23291/5686/2534/5710/695/6654/6233/2885/5716/7311/4794/3845/3265/3551/801/5693/7314 41 Human_hepatitis_A_virus_genotype_IB R-HSA-5654741 Signaling by FGFR3 23/1200 40/10654 1.6882203124724454e-12 1.4568278780356628e-11 6.959170960504744e-12 5295/4893/6464/5290/5335/5594/7316/673/6714/10818/2261/867/6654/6233/2885/7311/5518/3845/2549/3265/7314/5595/5515 23 Human_hepatitis_A_virus_genotype_IB R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 26/1200 51/10654 2.5869495972264163e-12 2.2168720854009706e-11 1.0589852152388839e-11 79861/11258/1783/10382/93661/55860/830/7277/10671/1780/5048/1781/8655/84516/1639/832/10121/7846/347733/51143/10540/10383/140735/829/51164/1778 26 Human_hepatitis_A_virus_genotype_IB R-HSA-5654743 Signaling by FGFR4 23/1200 41/10654 3.4383118096941722e-12 2.926121912525937e-11 1.3977891930517141e-11 5295/4893/6464/5290/5335/5594/7316/673/6714/10818/867/2264/6654/6233/2885/7311/5518/3845/2549/3265/7314/5595/5515 23 Human_hepatitis_A_virus_genotype_IB R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 32/1200 75/10654 3.81616363847483e-12 3.225442417724617e-11 1.5407726298095925e-11 5295/1839/685/5290/3667/5291/2065/2069/2064/2260/2100/1950/4233/6714/2099/10818/2261/5159/145957/3084/2534/2264/2066/9542/2885/10718/8660/3932/1956/2549/5156/5879 32 Human_hepatitis_A_virus_genotype_IB R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12/1200 12/10654 3.969640126932924e-12 3.3141475291657615e-11 1.5831464781479366e-11 1147/8737/57506/841/7706/8517/23586/843/64135/84282/8772/3551 12 Human_hepatitis_A_virus_genotype_IB R-HSA-6802952 Signaling by BRAF and RAF fusions 30/1200 67/10654 3.974828479064284e-12 3.3141475291657615e-11 1.5831464781479366e-11 4000/27044/818/815/4893/71/5604/10018/10142/283455/8844/817/5594/10533/673/6714/5037/3717/2335/3690/408/816/5894/4140/3845/3265/369/801/7529/5595 30 Human_hepatitis_A_virus_genotype_IB R-HSA-3371568 Attenuation phase 13/1200 14/10654 5.56138560154242e-12 4.6058723706733874e-11 2.2001949395010633e-11 3303/3337/3305/1387/3320/2033/3326/3306/3304/3312/3297/2288/10728 13 Human_hepatitis_A_virus_genotype_IB R-HSA-3371453 Regulation of HSF1-mediated heat shock response 30/1200 69/10654 1.0049577232088157e-11 8.26745220293119e-11 3.9493075438381525e-11 3303/6118/81929/7531/5594/9530/3308/545/3337/3313/10808/3305/9261/9532/6119/2932/3310/3309/7266/6767/9531/22824/3306/23411/6117/3304/3312/3297/51182/5595 30 Human_hepatitis_A_virus_genotype_IB R-HSA-389356 CD28 co-stimulation 20/1200 33/10654 1.2601591780820884e-11 1.0298254475187398e-10 4.919408433084485e-11 5295/5170/1326/5290/207/9020/6714/4067/10000/5063/2534/208/2885/7525/2475/3932/5058/5062/5879/253260 20 Human_hepatitis_A_virus_genotype_IB R-HSA-194315 Signaling by Rho GTPases 100/1200 455/10654 1.600041142035217e-11 1.298980769257538e-10 6.205145703183667e-11 26999/5170/11130/25/81929/5590/1072/3984/79861/54908/71/5579/1499/25936/7531/5747/80776/1783/10006/4627/2316/7532/10928/10458/4771/5578/10382/9212/5594/3985/613/1027/1080/2810/7277/79980/6232/7534/332/1780/5048/1781/8655/5289/5585/4168/10152/6279/6714/8936/1432/10163/7846/999/396/10810/347733/22919/55845/5063/9475/995/3895/79003/11243/23221/51143/695/6654/90627/8976/2885/5580/23191/7514/6093/57120/367/5518/10383/54820/5347/387/23332/5058/801/3071/9793/10726/30849/5586/5062/140735/9886/7529/10787/5879/5595/5515/1778 100 Human_hepatitis_A_virus_genotype_IB R-HSA-5675221 Negative regulation of MAPK pathway 22/1200 40/10654 1.7456871544655317e-11 1.4079594435362522e-10 6.725729662887498e-11 4893/5604/8844/5594/7316/673/8315/5037/5894/6233/7311/5518/5536/4140/1843/3845/3265/369/7529/7314/5595/5515 22 Human_hepatitis_A_virus_genotype_IB R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 33/1200 83/10654 1.8234707755462135e-11 1.4611447643013167e-10 6.979792442282156e-11 8454/1147/8945/5684/4893/4790/6885/5579/5966/5707/84433/6500/10892/8517/7316/5970/4792/4793/8915/5688/23291/5686/5710/6233/5716/7311/4794/3845/3265/3551/801/5693/7314 33 Human_hepatitis_A_virus_genotype_IB R-HSA-6806003 Regulation of TP53 Expression and Degradation 21/1200 37/10654 2.241856268655859e-11 1.7848068616266645e-10 8.525904994548597e-11 1017/5170/1029/6446/207/639/7316/983/4194/9099/10000/7157/208/6233/2475/7311/5518/7314/253260/4193/5515 21 Human_hepatitis_A_virus_genotype_IB R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 14/1200 17/10654 2.4180209424089876e-11 1.912716565982494e-10 9.136921239872017e-11 1147/11035/4790/8737/8517/4615/7098/5970/4792/4793/81030/3551/4791/148022 14 Human_hepatitis_A_virus_genotype_IB R-HSA-6807070 PTEN Regulation 45/1200 140/10654 2.4434127860060768e-11 1.9129300403760637e-10 9.137940993010284e-11 27161/3725/5684/5468/1822/1459/5707/2146/10273/207/6045/5594/1460/192670/7316/1457/8658/4734/10014/5688/10000/5686/5728/6009/2444/5710/6615/192669/3066/7157/1107/8975/5987/208/6233/2475/5716/7311/1386/331/26523/57521/5693/7314/5595 45 Human_hepatitis_A_virus_genotype_IB R-HSA-69620 Cell Cycle Checkpoints 73/1200 293/10654 2.449294541162221e-11 1.9129300403760637e-10 9.137940993010284e-11 1017/4172/6118/11130/81929/5684/54908/5883/25936/7531/51512/1029/80776/1783/7321/5707/7532/9212/1027/2810/545/79980/6232/7534/332/1780/5048/1781/7316/4174/8655/983/1026/641/4171/4194/6119/3364/10524/5688/22919/5686/995/79003/11243/5710/51143/1111/7157/6233/5716/672/7514/7311/9025/5518/54820/5347/6117/29882/7334/23332/7465/9793/10726/5810/5693/140735/7529/7314/4193/5515/1778 73 Human_hepatitis_A_virus_genotype_IB R-HSA-1169091 Activation of NF-kappaB in B cells 29/1200 67/10654 2.5505317903200778e-11 1.9794693265754566e-10 9.455794787019157e-11 8454/1147/8945/5684/4790/6885/5579/5966/5707/84433/6500/10892/8517/7316/5970/4792/4793/8915/5688/23291/5686/5710/6233/5716/7311/4794/3551/5693/7314 29 Human_hepatitis_A_virus_genotype_IB R-HSA-9006115 Signaling by NTRK2 (TRKB) 17/1200 25/10654 3.0434551426422445e-11 2.347264778762831e-10 1.121272947289248e-10 5295/4893/6464/5290/5335/4915/6714/10818/2534/6654/2885/8851/3845/2549/3265/1020/5879 17 Human_hepatitis_A_virus_genotype_IB R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 24/1200 48/10654 3.0944445586879196e-11 2.3717668232427903e-10 1.1329774127919155e-10 5295/6464/5290/1437/5291/1439/1438/7534/7316/3055/5566/867/3558/4067/3717/2534/6654/6233/2885/7525/1398/3716/7311/7314 24 Human_hepatitis_A_virus_genotype_IB R-HSA-3371378 Regulation by c-FLIP 11/1200 11/10654 3.5533120160594664e-11 2.641437968564688e-10 1.261797545335004e-10 7186/8737/356/355/841/8797/8837/8772/8717/8743/8795 11 Human_hepatitis_A_virus_genotype_IB R-HSA-5218900 CASP8 activity is inhibited 11/1200 11/10654 3.5533120160594664e-11 2.641437968564688e-10 1.261797545335004e-10 7186/8737/356/355/841/8797/8837/8772/8717/8743/8795 11 Human_hepatitis_A_virus_genotype_IB R-HSA-5655291 Signaling by FGFR4 in disease 11/1200 11/10654 3.5533120160594664e-11 2.641437968564688e-10 1.261797545335004e-10 5295/4893/5290/5335/10818/2264/6654/2885/3845/2549/3265 11 Human_hepatitis_A_virus_genotype_IB R-HSA-69416 Dimerization of procaspase-8 11/1200 11/10654 3.5533120160594664e-11 2.641437968564688e-10 1.261797545335004e-10 7186/8737/356/355/841/8797/8837/8772/8717/8743/8795 11 Human_hepatitis_A_virus_genotype_IB R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 11/1200 11/10654 3.5533120160594664e-11 2.641437968564688e-10 1.261797545335004e-10 6885/23118/7098/7316/10454/7189/6233/7311/7314/148022/257397 11 Human_hepatitis_A_virus_genotype_IB R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 30/1200 72/10654 3.7260842700221485e-11 2.746541541954959e-10 1.3120048310967986e-10 6517/8773/5563/79861/71/7531/4627/7532/207/10382/51422/2810/7277/53632/7534/8766/60412/149371/5571/7846/347733/208/10383/5564/801/5565/4218/7529/5879/55770 30 Human_hepatitis_A_virus_genotype_IB R-HSA-6785631 ERBB2 Regulates Cell Motility 13/1200 15/10654 3.739213768625876e-11 2.746541541954959e-10 1.3120048310967986e-10 1839/685/2065/2069/2064/1950/145957/3084/2066/9542/10718/387/1956 13 Human_hepatitis_A_virus_genotype_IB R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 12/1200 13/10654 4.628760039006821e-11 3.379816501854685e-10 1.6145161145087635e-10 2065/207/10193/2064/7316/10000/3084/208/9542/6233/7311/7314 12 Human_hepatitis_A_virus_genotype_IB R-HSA-388841 Costimulation by the CD28 family 29/1200 70/10654 9.349613855240762e-11 6.786719704333589e-10 3.2419713677615027e-10 5295/5170/1326/5290/207/3123/3126/3115/3122/9020/920/6714/4067/10000/5063/2534/208/2885/7525/2475/3932/5518/3127/3125/5058/5062/5879/253260/5515 29 Human_hepatitis_A_virus_genotype_IB R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 14/1200 18/10654 9.75056541645357e-11 6.995463792967271e-10 3.3416870460306e-10 1839/4893/5578/5594/5598/6195/6654/2885/6196/1956/6197/3845/3265/5595 14 Human_hepatitis_A_virus_genotype_IB R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 14/1200 18/10654 9.75056541645357e-11 6.995463792967271e-10 3.3416870460306e-10 23643/29110/7099/7316/929/3661/6233/10010/7311/7187/9641/353376/7314/148022 14 Human_hepatitis_A_virus_genotype_IB R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 20/1200 36/10654 1.1503775489396491e-10 8.1584246861582e-10 3.897225816129482e-10 26999/25/71/5747/10006/10458/5594/10152/8936/10163/10810/55845/695/8976/2885/23191/3071/10787/5879/5595 20 Human_hepatitis_A_virus_genotype_IB R-HSA-6804757 Regulation of TP53 Degradation 20/1200 36/10654 1.1503775489396491e-10 8.1584246861582e-10 3.897225816129482e-10 1017/5170/1029/6446/207/7316/983/4194/9099/10000/7157/208/6233/2475/7311/5518/7314/253260/4193/5515 20 Human_hepatitis_A_virus_genotype_IB R-HSA-8878166 Transcriptional regulation by RUNX2 40/1200 121/10654 1.1992597185910627e-10 8.456494244236408e-10 4.0396116836751585e-10 8454/7291/25/1019/5684/5707/10273/207/5594/3280/6500/5925/10013/7316/11059/9759/983/1026/10413/6714/2099/2932/5688/6502/2908/10000/5686/595/55294/5710/208/6233/7525/5716/7311/367/1750/5693/7314/5595 40 Human_hepatitis_A_virus_genotype_IB R-HSA-5218921 VEGFR2 mediated cell proliferation 15/1200 21/10654 1.5437488458908643e-10 1.0823784521757537e-9 5.170450680017248e-10 5170/5590/4893/5335/5579/7422/5578/3708/6714/5580/3791/3845/3265/801/8877 15 Human_hepatitis_A_virus_genotype_IB R-HSA-5687128 MAPK6/MAPK4 signaling 33/1200 89/10654 1.6610776308682454e-10 1.1580620319160536e-9 5.531986162867781e-10 2308/27161/3725/5684/2309/5707/5567/3315/3337/192670/5596/7316/983/5597/4609/5566/5688/5686/5063/5710/192669/6233/5716/7514/7311/5896/26523/5058/8202/5062/5693/7314/5879 33 Human_hepatitis_A_virus_genotype_IB R-HSA-114452 Activation of BH3-only proteins 18/1200 30/10654 1.7325508796005595e-10 1.2011054974309497e-9 5.737601966743425e-10 596/10018/7531/572/7532/207/2810/7534/8655/10000/7157/8626/208/7161/5599/7159/140735/7529 18 Human_hepatitis_A_virus_genotype_IB R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 16/1200 24/10654 1.864455068046243e-10 1.2853282424408178e-9 6.1399284804816e-10 596/1839/685/2309/5747/207/5594/2069/1027/1950/10000/595/208/7514/1956/5595 16 Human_hepatitis_A_virus_genotype_IB R-HSA-198323 AKT phosphorylates targets in the cytosol 12/1200 14/10654 2.9064488912122287e-10 1.981523719202149e-9 9.465608485483267e-10 1147/842/572/207/1027/7249/1026/2932/10000/208/2931/4193 12 Human_hepatitis_A_virus_genotype_IB R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 12/1200 14/10654 2.9064488912122287e-10 1.981523719202149e-9 9.465608485483267e-10 4893/1793/5753/1398/9844/387/9564/3845/3265/63916/5829/5879 12 Human_hepatitis_A_virus_genotype_IB R-HSA-187687 Signalling to ERKs 19/1200 34/10654 2.9509456663723417e-10 2.000806017749159e-9 9.557718757481268e-10 4893/6464/5604/5594/673/9261/6714/10818/7867/1432/4914/4803/6654/2885/1398/3845/3265/7529/5595 19 Human_hepatitis_A_virus_genotype_IB R-HSA-1250342 PI3K events in ERBB4 signaling 10/1200 10/10654 3.178273369658562e-10 2.108596418364874e-9 1.0072626412047508e-9 5295/1839/685/5290/2069/145957/3084/2066/9542/10718 10 Human_hepatitis_A_virus_genotype_IB R-HSA-193697 p75NTR regulates axonogenesis 10/1200 10/10654 3.178273369658562e-10 2.108596418364874e-9 1.0072626412047508e-9 4804/57142/4974/65078/4168/84894/396/4803/4099/387 10 Human_hepatitis_A_virus_genotype_IB R-HSA-8853334 Signaling by FGFR3 fusions in cancer 10/1200 10/10654 3.178273369658562e-10 2.108596418364874e-9 1.0072626412047508e-9 5295/4893/5290/10818/2261/6654/2885/3845/2549/3265 10 Human_hepatitis_A_virus_genotype_IB R-HSA-937042 IRAK2 mediated activation of TAK1 complex 10/1200 10/10654 3.178273369658562e-10 2.108596418364874e-9 1.0072626412047508e-9 6885/23118/7316/3656/10454/7189/6233/7311/7314/257397 10 Human_hepatitis_A_virus_genotype_IB R-HSA-3371511 HSF1 activation 11/1200 12/10654 3.8273140053087197e-10 2.5121837673143405e-9 1.2000536634786578e-9 6118/7531/1915/10013/7415/6119/3320/3326/6117/3297/10728 11 Human_hepatitis_A_virus_genotype_IB R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 11/1200 12/10654 3.8273140053087197e-10 2.5121837673143405e-9 1.2000536634786578e-9 29110/7098/7316/3661/6233/10010/7311/7187/9641/7314/148022 11 Human_hepatitis_A_virus_genotype_IB R-HSA-373755 Semaphorin interactions 27/1200 65/10654 3.870887686109996e-10 2.52734148394695e-9 1.2072944050245604e-9 1400/1072/3984/5361/4627/3985/10371/2064/8829/4233/2932/55558/3320/5063/2534/9475/91584/3326/6093/5362/387/8851/5058/1020/5062/5879/2242 27 Human_hepatitis_A_virus_genotype_IB R-HSA-9006335 Signaling by Erythropoietin 16/1200 25/10654 4.6379831636587235e-10 3.0122480126078236e-9 1.4389310646254212e-9 5295/4893/6464/5290/5335/5291/4067/23533/3717/5294/6654/2885/8660/3845/2549/3265 16 Human_hepatitis_A_virus_genotype_IB R-HSA-69206 G1/S Transition 41/1200 131/10654 4.731664934100493e-10 3.0570023710366535e-9 1.460309927305746e-9 8454/1017/4172/6118/1019/5684/5707/207/1027/6500/5925/4149/7316/4174/5753/983/1026/4171/4609/6119/5688/6502/10000/5686/1874/595/5710/208/6233/7298/5716/7311/5518/6117/7465/1163/1022/5693/7314/5515/6241 41 Human_hepatitis_A_virus_genotype_IB R-HSA-2559583 Cellular Senescence 53/1200 195/10654 4.966630561167481e-10 3.1920948502503497e-9 1.5248427161479109e-9 1017/7014/3725/25913/1019/4790/5606/9448/3159/1029/7321/2146/6045/5594/1027/5925/7013/50488/192670/3576/3490/7316/6774/5970/1026/9261/6667/7867/4194/5598/1432/10524/1021/6195/192669/7157/5609/6233/1030/51343/6196/7311/6197/29882/5599/4217/26523/5608/3569/7314/5595/4193/23043 53 Human_hepatitis_A_virus_genotype_IB R-HSA-5654736 Signaling by FGFR1 23/1200 50/10654 6.719858352924511e-10 4.296531195600438e-9 2.052424694648337e-9 5295/4893/6464/5290/5335/5594/2260/7316/673/6714/10818/867/6654/6233/2885/7311/5518/3845/2549/3265/7314/5595/5515 23 Human_hepatitis_A_virus_genotype_IB R-HSA-74751 Insulin receptor signalling cascade 24/1200 54/10654 6.8783608339785e-10 4.375204777901788e-9 2.090006547492111e-9 5295/5170/4893/6464/5290/3667/5291/5594/2322/2260/5289/10818/2261/2264/3630/208/6654/2885/8660/3845/2549/3265/30849/5595 24 Human_hepatitis_A_virus_genotype_IB R-HSA-5689880 Ub-specific processing proteases 57/1200 220/10654 8.094475087350008e-10 5.122349875789697e-9 2.4469128469182206e-9 23032/5684/7186/6885/51651/2648/5707/8737/7375/2625/9817/4303/91833/1080/330/3091/11274/27005/8517/7316/7417/4792/9738/8658/8678/9100/4609/4194/23586/5688/9097/329/7046/6502/9099/5686/408/64135/5728/5710/10454/7157/10869/8975/4087/7189/6233/5716/9804/7311/367/23770/8607/1540/5693/7314/4193 57 Human_hepatitis_A_virus_genotype_IB R-HSA-5205647 Mitophagy 17/1200 29/10654 9.380643338953918e-10 5.877952297270972e-9 2.807859154202631e-9 65018/1459/9140/8878/10452/1460/9474/7316/1457/6714/8408/81631/6233/9804/7311/84557/7314 17 Human_hepatitis_A_virus_genotype_IB R-HSA-1433557 Signaling by SCF-KIT 21/1200 43/10654 9.383765012661113e-10 5.877952297270972e-9 2.807859154202631e-9 5295/4893/5290/5578/2241/9306/6774/6714/867/4067/3717/2534/1111/6654/2885/7525/3932/3845/3265/5879/2242 21 Human_hepatitis_A_virus_genotype_IB R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 31/1200 85/10654 9.59200763955093e-10 5.978049205659519e-9 2.8556747890210106e-9 8454/1017/1019/5684/5707/207/1027/6500/5925/4149/7316/5753/1026/4609/5688/6502/10000/5686/1874/595/5710/208/6233/5716/51343/7311/7465/1163/1022/5693/7314 31 Human_hepatitis_A_virus_genotype_IB R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 19/1200 36/10654 1.0946966510021888e-9 6.788219433852768e-9 3.2426877786893713e-9 4893/71/5604/283455/8844/5594/673/6714/5037/2335/3690/408/5894/4140/3845/3265/369/7529/5595 19 Human_hepatitis_A_virus_genotype_IB R-HSA-9006931 Signaling by Nuclear Receptors 70/1200 299/10654 1.2087709577646363e-9 7.458116809407805e-9 3.562693349201033e-9 5295/5170/27161/3725/596/5434/5590/1839/4893/6464/685/857/5290/7090/5241/2309/5747/8204/207/2625/5594/2069/1027/3315/5481/6720/192670/5885/2100/4313/1950/2194/6667/2289/6714/2099/4609/10524/1387/5467/10000/3320/2033/8243/4846/9126/595/192669/2066/2771/208/3326/7514/1025/1386/1956/5536/3169/3845/858/3265/26523/801/8202/8877/3480/2288/10728/10062/5595 70 Human_hepatitis_A_virus_genotype_IB R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 12/1200 15/10654 1.3036558948610759e-9 8.003539175415759e-9 3.8232380263011385e-9 6737/29110/81844/23220/147945/7316/22954/3661/6233/7311/81030/7314 12 Human_hepatitis_A_virus_genotype_IB R-HSA-2559585 Oncogene Induced Senescence 18/1200 33/10654 1.4897938891292063e-9 9.101018114779409e-9 4.347496497719414e-9 1019/1029/5594/5925/192670/7316/6667/4194/1021/192669/7157/6233/1030/7311/26523/7314/5595/4193 18 Human_hepatitis_A_virus_genotype_IB R-HSA-68882 Mitotic Anaphase 53/1200 201/10654 1.6274346891814682e-9 9.892878849507053e-9 4.725763162777403e-9 4000/11130/81929/5684/79861/54908/25936/80776/55869/1783/7321/5707/10382/9212/7277/79980/6232/332/1780/5885/5048/1781/7316/8655/5688/7846/347733/22919/5686/79003/8243/9126/11243/5710/51143/6233/5716/7514/7311/5518/10383/54820/5347/29882/23332/9793/10726/7112/5693/140735/7314/5515/1778 53 Human_hepatitis_A_virus_genotype_IB R-HSA-2467813 Separation of Sister Chromatids 51/1200 190/10654 1.6990172467467892e-9 1.0277388639634989e-8 4.909440960671836e-9 11130/81929/5684/79861/54908/25936/80776/55869/1783/7321/5707/10382/9212/7277/79980/6232/332/1780/5885/5048/1781/7316/8655/5688/7846/347733/22919/5686/79003/8243/9126/11243/5710/51143/6233/5716/7514/7311/5518/10383/54820/5347/29882/23332/9793/10726/5693/140735/7314/5515/1778 51 Human_hepatitis_A_virus_genotype_IB R-HSA-2500257 Resolution of Sister Chromatid Cohesion 39/1200 126/10654 1.7986158633189273e-9 1.082679012358808e-8 5.171886436244412e-9 11130/81929/79861/54908/25936/80776/55869/1783/10382/9212/7277/79980/6232/332/1780/5885/5048/1781/8655/983/7846/347733/22919/79003/8243/9126/11243/51143/7514/5518/10383/54820/5347/23332/9793/10726/140735/5515/1778 39 Human_hepatitis_A_virus_genotype_IB R-HSA-2555396 Mitotic Metaphase and Anaphase 53/1200 202/10654 1.970893686714957e-9 1.180622723012746e-8 5.639757100461807e-9 4000/11130/81929/5684/79861/54908/25936/80776/55869/1783/7321/5707/10382/9212/7277/79980/6232/332/1780/5885/5048/1781/7316/8655/5688/7846/347733/22919/5686/79003/8243/9126/11243/5710/51143/6233/5716/7514/7311/5518/10383/54820/5347/29882/23332/9793/10726/7112/5693/140735/7314/5515/1778 53 Human_hepatitis_A_virus_genotype_IB R-HSA-69202 Cyclin E associated events during G1/S transition 30/1200 83/10654 2.2925447439600503e-9 1.3666667700708706e-8 6.528477277486032e-9 8454/1017/1019/5684/5707/207/1027/6500/5925/4149/7316/5753/1026/4609/5688/6502/10000/5686/1874/595/5710/208/6233/5716/7311/7465/1163/1022/5693/7314 30 Human_hepatitis_A_virus_genotype_IB R-HSA-2428924 IGF1R signaling cascade 23/1200 53/10654 2.7734867814095425e-9 1.6454243693554688e-8 7.86008399589749e-9 5295/5170/4893/6464/5290/3667/5291/2322/2260/5289/10818/2261/8471/2264/208/6654/2885/8660/3845/2549/3265/30849/3480 23 Human_hepatitis_A_virus_genotype_IB R-HSA-177929 Signaling by EGFR 22/1200 49/10654 2.802434402876763e-9 1.654643087631543e-8 7.904121206804267e-9 5295/1839/4893/6464/685/5290/5335/2069/7316/1950/6714/867/6654/6233/2885/7311/1956/3845/2549/3265/5829/7314 22 Human_hepatitis_A_virus_genotype_IB R-HSA-5603041 IRAK4 deficiency (TLR2/4) 10/1200 11/10654 3.1407695050184824e-9 1.8281648911286827e-8 8.733023449902434e-9 23643/10333/7099/4615/7096/929/114609/695/51135/7097 10 Human_hepatitis_A_virus_genotype_IB R-HSA-9614399 Regulation of localization of FOXO transcription factors 10/1200 11/10654 3.1407695050184824e-9 1.8281648911286827e-8 8.733023449902434e-9 2308/2309/7532/207/4303/2810/7534/10000/208/7529 10 Human_hepatitis_A_virus_genotype_IB R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 10/1200 11/10654 3.1407695050184824e-9 1.8281648911286827e-8 8.733023449902434e-9 6885/23118/7316/80216/10454/7189/6233/7311/7314/257397 10 Human_hepatitis_A_virus_genotype_IB R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 35/1200 108/10654 3.1577354405370386e-9 1.8294110486491574e-8 8.73897626242027e-9 5295/7124/2308/7291/596/2309/7412/7184/356/207/5292/7422/2625/4582/3091/6778/3576/332/4313/6774/1026/4609/3717/598/3320/4843/2335/595/7157/3716/604/3312/7297/3569/4170 35 Human_hepatitis_A_virus_genotype_IB R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 23/1200 54/10654 4.320905041224671e-9 2.491587299472544e-8 1.1902148662497863e-8 5295/5170/4893/6464/5290/3667/5291/2322/2260/5289/10818/2261/8471/2264/208/6654/2885/8660/3845/2549/3265/30849/3480 23 Human_hepatitis_A_virus_genotype_IB R-HSA-1295596 Spry regulation of FGF signaling 12/1200 16/10654 4.67825654409293e-9 2.6726706367642015e-8 1.276717185522437e-8 5594/7316/673/6714/867/6233/2885/7311/5518/7314/5595/5515 12 Human_hepatitis_A_virus_genotype_IB R-HSA-399956 CRMPs in Sema3A signaling 12/1200 16/10654 4.67825654409293e-9 2.6726706367642015e-8 1.276717185522437e-8 1400/5361/10371/8829/2932/55558/2534/91584/5362/8851/1020/2242 12 Human_hepatitis_A_virus_genotype_IB R-HSA-912631 Regulation of signaling by CBL 14/1200 22/10654 6.573646133311859e-9 3.738193238943241e-8 1.7857103248385356e-8 5295/5290/5291/7316/3055/867/4067/2534/6233/2885/7525/1398/7311/7314 14 Human_hepatitis_A_virus_genotype_IB R-HSA-2871796 FCERI mediated MAPK activation 17/1200 32/10654 7.3403594024715705e-9 4.1550474782797784e-8 1.984838853396465e-8 3725/4893/6464/5335/5594/4214/4067/5609/6654/2885/3845/5599/3265/5058/5062/5879/5595 17 Human_hepatitis_A_virus_genotype_IB R-HSA-193704 p75 NTR receptor-mediated signalling 32/1200 97/10654 9.126884686929417e-9 5.142728631813197e-8 2.4566476446433422e-8 4804/57142/4790/5584/10018/7531/572/8767/4974/8878/4615/7316/5970/4792/65078/4168/84894/836/396/4803/3066/3654/7189/6654/4099/6233/7311/387/5599/3551/7314/5879 32 Human_hepatitis_A_virus_genotype_IB R-HSA-180336 SHC1 events in EGFR signaling 11/1200 14/10654 9.355772812646941e-9 5.223992602174808e-8 2.4954669088270003e-8 1839/4893/6464/685/2069/1950/6654/2885/1956/3845/3265 11 Human_hepatitis_A_virus_genotype_IB R-HSA-918233 TRAF3-dependent IRF activation pathway 11/1200 14/10654 9.355772812646941e-9 5.223992602174808e-8 2.4954669088270003e-8 29110/57506/7706/23586/1387/2033/64135/3661/84282/7187/9641 11 Human_hepatitis_A_virus_genotype_IB R-HSA-186763 Downstream signal transduction 16/1200 29/10654 9.913094872296503e-9 5.461053157327627e-8 2.6087091769201326e-8 5295/4893/5290/5335/5291/6778/6774/6714/5159/6654/2885/1398/9564/3845/3265/5156 16 Human_hepatitis_A_virus_genotype_IB R-HSA-5218920 VEGFR2 mediated vascular permeability 16/1200 29/10654 9.913094872296503e-9 5.461053157327627e-8 2.6087091769201326e-8 5170/857/1499/207/10000/3320/5063/4846/3728/208/2475/5058/801/5062/5879/253260 16 Human_hepatitis_A_virus_genotype_IB R-HSA-9619483 Activation of AMPK downstream of NMDARs 16/1200 29/10654 9.913094872296503e-9 5.461053157327627e-8 2.6087091769201326e-8 5563/79861/10382/51422/7277/53632/10645/5571/7846/347733/4137/5562/10383/5564/801/5565 16 Human_hepatitis_A_virus_genotype_IB R-HSA-165159 mTOR signalling 19/1200 40/10654 1.0723904100576146e-8 5.855441442526975e-8 2.7971058669411466e-8 5563/6194/207/51422/7249/53632/6198/5571/6794/6009/208/2475/5562/92335/5564/5565/57521/7248/7529 19 Human_hepatitis_A_virus_genotype_IB R-HSA-5674135 MAP2K and MAPK activation 19/1200 40/10654 1.0723904100576146e-8 5.855441442526975e-8 2.7971058669411466e-8 4893/71/5604/283455/8844/5594/673/6714/5037/2335/3690/408/5894/4140/3845/3265/369/7529/5595 19 Human_hepatitis_A_virus_genotype_IB R-HSA-2428928 IRS-related events triggered by IGF1R 22/1200 52/10654 1.0918561742829671e-8 5.9354648416968345e-8 2.835332518425511e-8 5295/5170/4893/5290/3667/5291/2322/2260/5289/10818/2261/8471/2264/208/6654/2885/8660/3845/2549/3265/30849/3480 22 Human_hepatitis_A_virus_genotype_IB R-HSA-9034015 Signaling by NTRK3 (TRKC) 12/1200 17/10654 1.427102996322914e-8 7.723882006414369e-8 3.689647635922585e-8 5295/4893/6464/5290/3667/5335/6714/6654/2885/3845/3265/4916 12 Human_hepatitis_A_virus_genotype_IB R-HSA-2562578 TRIF-mediated programmed cell death 9/1200 10/10654 2.5546539710393294e-8 1.3706273914184924e-7 6.54739690518089e-8 23643/11035/8737/841/7099/929/8772/353376/148022 9 Human_hepatitis_A_virus_genotype_IB R-HSA-5602498 MyD88 deficiency (TLR2/4) 9/1200 10/10654 2.5546539710393294e-8 1.3706273914184924e-7 6.54739690518089e-8 23643/10333/7099/4615/7096/929/114609/695/7097 9 Human_hepatitis_A_virus_genotype_IB R-HSA-5628897 TP53 Regulates Metabolic Genes 29/1200 86/10654 2.5908185193154e-8 1.3840130098853695e-7 6.611339124249823e-8 27161/5563/7531/7532/207/51422/7249/2810/53632/192670/7534/54205/5571/10000/10128/5728/6009/192669/7157/8626/208/2475/5562/26523/5564/5565/57521/7248/7529 29 Human_hepatitis_A_virus_genotype_IB R-HSA-9006936 Signaling by TGF-beta family members 32/1200 102/10654 3.5815446272845515e-8 1.9050112370987657e-7 9.100113390559658e-8 5590/7321/10273/4738/269/130399/54778/7316/91/93/6667/4609/22938/23327/867/23645/7046/1874/94/9040/4087/5499/657/6233/7514/7048/1025/1030/7311/387/23439/7314 32 Human_hepatitis_A_virus_genotype_IB R-HSA-445144 Signal transduction by L1 13/1200 21/10654 3.766224917028263e-8 1.991820689041695e-7 9.514796433194143e-8 5604/1459/5594/1460/2260/8829/1457/3690/3685/1956/5058/5879/5595 13 Human_hepatitis_A_virus_genotype_IB R-HSA-69242 S Phase 43/1200 161/10654 3.777034369819746e-8 1.991820689041695e-7 9.514796433194143e-8 8454/1017/4172/6118/1019/5684/7321/5707/207/1027/6500/5925/4149/5885/7316/4174/5753/1026/4171/4609/6119/2932/5688/6502/10000/5686/1874/8243/9126/595/5710/208/6233/5716/51343/7311/6117/29882/7465/1163/1022/5693/7314 43 Human_hepatitis_A_virus_genotype_IB R-HSA-170834 Signaling by TGF-beta Receptor Complex 26/1200 73/10654 3.801665268754896e-8 1.9962786985717198e-7 9.536092051524038e-8 5590/7321/10273/4738/54778/7316/6667/4609/22938/23327/867/23645/7046/1874/9040/4087/5499/6233/7514/7048/1025/1030/7311/387/23439/7314 26 Human_hepatitis_A_virus_genotype_IB R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 20/1200 47/10654 4.523944933432344e-8 2.3654864609557255e-7 1.1299773250321644e-7 8454/7090/2648/55869/3280/6500/3091/10013/7316/9759/4609/10014/22938/1387/2033/55294/3066/6233/7311/7314 20 Human_hepatitis_A_virus_genotype_IB R-HSA-8948751 Regulation of PTEN stability and activity 25/1200 69/10654 4.684012106885404e-8 2.438848497846662e-7 1.1650218875664339e-7 5684/1459/5707/10273/207/1460/7316/1457/8658/4734/5688/10000/5686/5728/2444/5710/8975/5987/208/6233/5716/7311/331/5693/7314 25 Human_hepatitis_A_virus_genotype_IB R-HSA-179812 GRB2 events in EGFR signaling 10/1200 13/10654 6.592358578129361e-8 3.418054825803207e-7 1.632782310372597e-7 1839/4893/685/2069/1950/6654/2885/1956/3845/3265 10 Human_hepatitis_A_virus_genotype_IB R-HSA-112399 IRS-mediated signalling 20/1200 48/10654 6.940597176527028e-8 3.583555194909771e-7 1.7118407482295247e-7 5295/5170/4893/5290/3667/5291/2322/2260/5289/10818/2261/2264/208/6654/2885/8660/3845/2549/3265/30849 20 Human_hepatitis_A_virus_genotype_IB R-HSA-390466 Chaperonin-mediated protein folding 30/1200 95/10654 8.091071006393912e-8 4.16015900912087e-7 1.987280598061663e-7 10694/26224/6000/79861/2629/1459/10575/10382/1460/7277/10576/908/8786/6774/1457/26272/26270/6950/7846/347733/55294/26190/7157/2771/10574/10383/54461/22948/8877/9628 30 Human_hepatitis_A_virus_genotype_IB R-HSA-8878159 Transcriptional regulation by RUNX3 30/1200 96/10654 1.05203187208605e-7 5.386752407278779e-7 2.5732161972840707e-7 8463/5684/2309/1499/2648/10018/1029/5707/3280/7316/9759/1026/10413/6714/4609/22938/5688/1387/5686/2033/595/5710/7157/6233/5716/7311/3845/5693/7314/4193 30 Human_hepatitis_A_virus_genotype_IB R-HSA-8934903 Receptor Mediated Mitophagy 9/1200 11/10654 1.2637250563457977e-7 6.443953386490555e-7 3.078234152038481e-7 1459/9140/1460/9474/1457/6714/8408/81631/84557 9 Human_hepatitis_A_virus_genotype_IB R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 26/1200 77/10654 1.31627341972654e-7 6.6842855964714e-7 3.1930392681258926e-7 5684/79861/51512/5707/63943/10382/7277/7316/983/1026/5688/7846/347733/3320/22919/5686/5710/7157/6233/3326/5716/7311/10383/5347/5693/7314 26 Human_hepatitis_A_virus_genotype_IB R-HSA-190236 Signaling by FGFR 28/1200 87/10654 1.391485913310191e-7 7.037268922232687e-7 3.3616570813360957e-7 5295/5434/4893/6464/5290/5335/5594/3178/2260/7316/673/6714/10818/2261/867/4670/2264/6654/6233/2885/7311/5518/3845/2549/3265/7314/5595/5515 28 Human_hepatitis_A_virus_genotype_IB R-HSA-5663220 RHO GTPases Activate Formins 38/1200 140/10654 1.4745829169263355e-7 7.427082936682032e-7 3.547868672303965e-7 11130/81929/79861/54908/71/25936/80776/1783/10382/9212/7277/79980/6232/332/1780/5048/1781/8655/6714/7846/347733/22919/79003/11243/51143/7514/5518/10383/54820/5347/387/23332/9793/10726/140735/5879/5515/1778 38 Human_hepatitis_A_virus_genotype_IB R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 15/1200 30/10654 1.6423861686084933e-7 8.238636309198702e-7 3.9355423809189396e-7 818/5170/815/4893/817/5594/27330/6195/816/6196/6197/3845/3265/801/5595 15 Human_hepatitis_A_virus_genotype_IB R-HSA-5654738 Signaling by FGFR2 25/1200 73/10654 1.6760414940622584e-7 8.373421877217923e-7 3.999928560302001e-7 5295/5434/4893/6464/5290/5335/5594/3178/7316/673/6714/10818/867/4670/6654/6233/2885/7311/5518/3845/2549/3265/7314/5595/5515 25 Human_hepatitis_A_virus_genotype_IB R-HSA-1489509 DAG and IP3 signaling 18/1200 42/10654 1.8770632389822532e-7 9.302393722506429e-7 4.4436923011205316e-7 818/815/5335/5567/817/5578/5582/3708/10645/5566/84254/816/5613/5577/5580/5581/801/814 18 Human_hepatitis_A_virus_genotype_IB R-HSA-3928662 EPHB-mediated forward signaling 18/1200 42/10654 1.8770632389822532e-7 9.302393722506429e-7 4.4436923011205316e-7 1072/3984/71/5747/3985/2051/6714/4067/2047/2534/9475/8976/7525/6093/387/3265/5058/5879 18 Human_hepatitis_A_virus_genotype_IB R-HSA-5696394 DNA Damage Recognition in GG-NER 17/1200 38/10654 1.9263020518879472e-7 9.508226928118907e-7 4.542017469714739e-7 10445/8450/7316/10980/4798/1642/10987/1069/6233/7311/8533/8607/5886/50813/7314/51138/8451 17 Human_hepatitis_A_virus_genotype_IB R-HSA-167044 Signalling to RAS 12/1200 20/10654 2.0991439399942477e-7 1.0320094111366143e-6 4.929841083651828e-7 4893/6464/9261/6714/7867/1432/4914/4803/6654/2885/3845/3265 12 Human_hepatitis_A_virus_genotype_IB R-HSA-180292 GAB1 signalosome 11/1200 17/10654 2.302671012606937e-7 1.1275777895067303e-6 5.386364941770612e-7 5295/1839/685/5290/2069/1950/6714/2885/1956/2549/5829 11 Human_hepatitis_A_virus_genotype_IB R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 15/1200 31/10654 2.8518970530516666e-7 1.3910043333856747e-6 6.644736216804382e-7 3725/9252/5594/9261/5598/1432/6195/6196/5518/1386/6197/5599/51231/5595/5515 15 Human_hepatitis_A_virus_genotype_IB R-HSA-1234174 Cellular response to hypoxia 25/1200 75/10654 3.0370319195339597e-7 1.4754714128759474e-6 7.048229900286023e-7 5684/64344/112399/7321/5707/84962/7422/3091/7316/7322/5688/1387/5686/2033/5710/7428/8453/6233/5716/7311/2034/54583/405/5693/7314 25 Human_hepatitis_A_virus_genotype_IB R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 17/1200 39/10654 3.0585433358370247e-7 1.4800950887932895e-6 7.070316896052564e-7 10694/26224/2629/10575/10576/908/6774/26272/26270/6950/55294/26190/7157/10574/54461/22948/8877 17 Human_hepatitis_A_virus_genotype_IB R-HSA-391251 Protein folding 30/1200 101/10654 3.653982838334753e-7 1.7613339150410488e-6 8.413776272481338e-7 10694/26224/6000/79861/2629/1459/10575/10382/1460/7277/10576/908/8786/6774/1457/26272/26270/6950/7846/347733/55294/26190/7157/2771/10574/10383/54461/22948/8877/9628 30 Human_hepatitis_A_virus_genotype_IB R-HSA-2132295 MHC class II antigen presentation 34/1200 123/10654 4.149315327370987e-7 1.9923171649711275e-6 9.51716806605674e-7 79861/11258/1783/10382/93661/821/55860/830/3123/7277/3126/10671/1780/3115/1781/3122/8655/84516/1639/832/10121/7846/347733/51143/10540/1213/10383/3127/3125/7879/140735/829/51164/1778 34 Human_hepatitis_A_virus_genotype_IB R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 9/1200 12/10654 4.546971424559493e-7 2.1747917588784548e-6 1.0388837200135927e-6 5295/5290/5291/4067/23533/3717/5294/8660/2549 9 Human_hepatitis_A_virus_genotype_IB R-HSA-2173789 TGF-beta receptor signaling activates SMADs 15/1200 32/10654 4.811442520702951e-7 2.2924015716399386e-6 1.0950651540717955e-6 10273/4738/7316/23327/867/23645/7046/9040/4087/5499/6233/7514/7048/7311/7314 15 Human_hepatitis_A_virus_genotype_IB R-HSA-111447 Activation of BAD and translocation to mitochondria 10/1200 15/10654 5.590311659356168e-7 2.6430822174887015e-6 1.2625829922320846e-6 596/7531/572/7532/207/2810/7534/10000/208/7529 10 Human_hepatitis_A_virus_genotype_IB R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 10/1200 15/10654 5.590311659356168e-7 2.6430822174887015e-6 1.2625829922320846e-6 4615/7316/7335/3654/7189/6233/51135/7311/7334/7314 10 Human_hepatitis_A_virus_genotype_IB R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 44/1200 182/10654 5.801497554102461e-7 2.7324610617413882e-6 1.3052786783034866e-6 81929/5893/5241/5468/1029/8204/6045/9212/4869/8517/332/3183/5465/5885/4306/5970/4792/3190/9759/8856/6790/641/2099/1387/2908/2033/8243/9126/7022/7428/3066/7157/1107/1069/5987/672/367/7155/25942/9641/6117/4791/10062/4193 44 Human_hepatitis_A_virus_genotype_IB R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 13/1200 25/10654 6.229711082252922e-7 2.9229899146388236e-6 1.3962930582596102e-6 10694/79861/10575/10382/7277/10576/908/6950/7846/347733/10574/10383/22948 13 Human_hepatitis_A_virus_genotype_IB R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK 14/1200 29/10654 7.420843115803189e-7 3.4426016559778704e-6 1.6445081697070779e-6 5563/51422/7249/53632/5571/6794/6009/2475/5562/92335/5564/5565/57521/7248 14 Human_hepatitis_A_virus_genotype_IB R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 14/1200 29/10654 7.420843115803189e-7 3.4426016559778704e-6 1.6445081697070779e-6 11022/5434/8468/91646/122402/56165/55124/84944/3320/54514/54456/143689/9271/136991 14 Human_hepatitis_A_virus_genotype_IB R-HSA-5654732 Negative regulation of FGFR3 signaling 14/1200 29/10654 7.420843115803189e-7 3.4426016559778704e-6 1.6445081697070779e-6 5594/7316/673/6714/10818/2261/867/6233/2885/7311/5518/7314/5595/5515 14 Human_hepatitis_A_virus_genotype_IB R-HSA-9022692 Regulation of MECP2 expression and activity 15/1200 33/10654 7.906441257617895e-7 3.6541380194383834e-6 1.745557699296677e-6 818/27161/815/817/9212/192670/5566/3064/816/192669/3066/25942/26523/801/814 15 Human_hepatitis_A_virus_genotype_IB R-HSA-389357 CD28 dependent PI3K/Akt signaling 12/1200 22/10654 8.680030140291284e-7 3.967095256710906e-6 1.8950553132799686e-6 5295/5170/1326/5290/207/9020/10000/2534/208/2475/3932/253260 12 Human_hepatitis_A_virus_genotype_IB R-HSA-5205685 Pink/Parkin Mediated Mitophagy 12/1200 22/10654 8.680030140291284e-7 3.967095256710906e-6 1.8950553132799686e-6 65018/9140/8878/10452/9474/7316/81631/6233/9804/7311/84557/7314 12 Human_hepatitis_A_virus_genotype_IB R-HSA-9613829 Chaperone Mediated Autophagy 12/1200 22/10654 8.680030140291284e-7 3.967095256710906e-6 1.8950553132799686e-6 1915/1080/10013/5116/7316/3920/3320/6233/3326/7311/3312/7314 12 Human_hepatitis_A_virus_genotype_IB R-HSA-74749 Signal attenuation 8/1200 10/10654 9.258750475099291e-7 4.215977153606098e-6 2.013944558576657e-6 6464/3667/5594/3630/6654/2885/8660/5595 8 Human_hepatitis_A_virus_genotype_IB R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 21/1200 60/10654 1.0759467359611126e-6 4.8813171771176945e-6 2.331773111990027e-6 8454/1017/1019/5684/5707/1027/6500/7316/5753/1026/5688/6502/5686/595/5710/6233/5716/7311/1163/5693/7314 21 Human_hepatitis_A_virus_genotype_IB R-HSA-400253 Circadian Clock 23/1200 70/10654 1.1986106896837245e-6 5.4178959379843076e-6 2.588093257076868e-6 8454/26224/8945/8204/1454/4862/6500/3091/1408/6720/5465/406/7316/1387/2908/2033/5499/6233/7311/1386/23411/1453/7314 23 Human_hepatitis_A_virus_genotype_IB R-HSA-111465 Apoptotic cleavage of cellular proteins 16/1200 38/10654 1.2078222212701408e-6 5.4198277128994684e-6 2.589016053248914e-6 4000/51765/1499/5747/841/7082/660/10134/329/999/5588/836/4137/5580/6709/6093 16 Human_hepatitis_A_virus_genotype_IB R-HSA-111996 Ca-dependent events 16/1200 38/10654 1.2078222212701408e-6 5.4198277128994684e-6 2.589016053248914e-6 818/815/5567/817/5578/5594/5582/10645/5566/84254/816/5613/5577/5580/801/814 16 Human_hepatitis_A_virus_genotype_IB R-HSA-6807878 COPI-mediated anterograde transport 29/1200 101/10654 1.2429371907211293e-6 5.557190193296643e-6 2.65463320672705e-6 11014/79861/11258/1783/10382/93661/55860/830/7277/10671/1780/1781/8655/84516/1639/832/10121/8775/7846/347733/51143/3630/10540/6709/10383/140735/829/51164/1778 29 Human_hepatitis_A_virus_genotype_IB R-HSA-2424491 DAP12 signaling 14/1200 30/10654 1.2476992944598397e-6 5.558342705283185e-6 2.655183754123162e-6 5295/4893/6464/5290/5335/5291/2534/695/6654/2885/3932/3845/3265/5879 14 Human_hepatitis_A_virus_genotype_IB R-HSA-913531 Interferon Signaling 46/1200 199/10654 1.2604743979239912e-6 5.595055421000738e-6 2.6727211769687054e-6 818/815/81929/6737/51447/5335/23321/4281/7412/10410/2316/817/3123/9636/11274/7706/3126/2634/51127/3115/7316/3122/4734/3434/3659/23586/3717/3458/816/3661/51191/6233/5580/3716/7311/10107/5610/3127/3125/7334/6773/7297/3660/5495/7314/5595 46 Human_hepatitis_A_virus_genotype_IB R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 9/1200 13/10654 1.3294376449739258e-6 5.842567969216629e-6 2.7909562934072435e-6 7531/7532/2810/7534/983/995/1111/7465/7529 9 Human_hepatitis_A_virus_genotype_IB R-HSA-141424 Amplification of signal from the kinetochores 28/1200 96/10654 1.3374298719124626e-6 5.842567969216629e-6 2.7909562934072435e-6 11130/81929/54908/25936/80776/1783/9212/79980/6232/332/1780/5048/1781/8655/22919/79003/11243/51143/7514/5518/54820/5347/23332/9793/10726/140735/5515/1778 28 Human_hepatitis_A_virus_genotype_IB R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 28/1200 96/10654 1.3374298719124626e-6 5.842567969216629e-6 2.7909562934072435e-6 11130/81929/54908/25936/80776/1783/9212/79980/6232/332/1780/5048/1781/8655/22919/79003/11243/51143/7514/5518/54820/5347/23332/9793/10726/140735/5515/1778 28 Human_hepatitis_A_virus_genotype_IB R-HSA-1433559 Regulation of KIT signaling 10/1200 16/10654 1.339908213361674e-6 5.842567969216629e-6 2.7909562934072435e-6 5578/9306/6714/867/4067/2534/6654/2885/7525/3932 10 Human_hepatitis_A_virus_genotype_IB R-HSA-9614657 FOXO-mediated transcription of cell death genes 10/1200 16/10654 1.339908213361674e-6 5.842567969216629e-6 2.7909562934072435e-6 2308/2309/65018/10018/356/4303/1387/6794/2033/604 10 Human_hepatitis_A_virus_genotype_IB R-HSA-76002 Platelet activation, signaling and aggregation 56/1200 262/10654 1.361919127210335e-6 5.917634517526597e-6 2.826815089836129e-6 5295/5170/5590/351/1072/6464/5290/5579/5291/5747/2316/207/3959/7422/5578/5594/5582/7277/3708/5583/7534/1950/308/6714/6647/146850/1432/3920/226/4067/23533/5588/3309/2335/5294/2534/3690/408/55664/2768/87/5894/2771/10487/6654/2885/1398/5580/3932/387/5581/9564/10916/801/5879/5595 56 Human_hepatitis_A_virus_genotype_IB R-HSA-2990846 SUMOylation 44/1200 188/10654 1.4983302733747017e-6 6.487507218752218e-6 3.0990395312643876e-6 81929/5893/5241/5468/1029/8204/6045/9212/4869/8517/332/3183/5465/5885/4306/5970/4792/3190/9759/8856/6790/641/2099/1387/2908/2033/8243/9126/7022/7428/3066/7157/1107/1069/5987/672/367/7155/25942/9641/6117/4791/10062/4193 44 Human_hepatitis_A_virus_genotype_IB R-HSA-2682334 EPH-Ephrin signaling 27/1200 92/10654 1.802805848586834e-6 7.77853992012641e-6 3.71575736182785e-6 1072/3984/71/5747/4627/3985/4313/2051/2041/6714/4067/2043/2047/5063/2534/9475/6386/8976/7525/6093/1213/387/3265/5058/5062/1969/5879 27 Human_hepatitis_A_virus_genotype_IB R-HSA-8986944 Transcriptional Regulation by MECP2 21/1200 62/10654 1.98771054497059e-6 8.546462761302118e-6 4.082589052571173e-6 818/27161/815/5468/6446/817/9212/192670/4233/2289/5566/3064/5728/816/192669/3066/3654/25942/26523/801/814 21 Human_hepatitis_A_virus_genotype_IB R-HSA-5654733 Negative regulation of FGFR4 signaling 14/1200 31/10654 2.0403542502342963e-6 8.742351197184451e-6 4.1761636700701975e-6 5594/7316/673/6714/10818/867/2264/6233/2885/7311/5518/7314/5595/5515 14 Human_hepatitis_A_virus_genotype_IB R-HSA-622312 Inflammasomes 11/1200 20/10654 2.2639982831085893e-6 9.667037651750862e-6 4.617880307925004e-6 596/351/4790/10910/29108/5970/598/3326/4210/114548/4791 11 Human_hepatitis_A_virus_genotype_IB R-HSA-5358351 Signaling by Hedgehog 37/1200 149/10654 2.2963773325310355e-6 9.771481477045855e-6 4.667772436360725e-6 8454/8945/5684/2735/54903/5707/5567/1452/10382/6500/79577/7277/8452/7316/7415/5566/8405/2932/5688/7846/347733/5686/408/5710/83737/5577/6233/5716/7311/51009/10383/23432/23322/8481/5693/5034/7314 37 Human_hepatitis_A_virus_genotype_IB R-HSA-1236974 ER-Phagosome pathway 25/1200 83/10654 2.5608984738934247e-6 1.0859617583451842e-5 5.187567897921208e-6 23643/1147/8773/5684/5707/811/10333/7099/8517/4615/7316/7096/5688/929/5686/114609/5710/695/6233/5716/7311/7097/3551/5693/7314 25 Human_hepatitis_A_virus_genotype_IB R-HSA-74752 Signaling by Insulin receptor 24/1200 78/10654 2.6640725524131378e-6 1.1258443594787027e-5 5.378084460531208e-6 5295/5170/4893/6464/5290/3667/5291/5594/2322/2260/5289/10818/2261/2264/3630/208/6654/2885/8660/3845/2549/3265/30849/5595 24 Human_hepatitis_A_virus_genotype_IB R-HSA-1980143 Signaling by NOTCH1 23/1200 73/10654 2.724701890376589e-6 1.1475365640698672e-5 5.4817066952070765e-6 8454/7090/2648/55869/3280/23220/6500/3091/10013/7316/9759/4609/10014/22938/1387/2033/408/55294/3066/83737/6233/7311/7314 23 Human_hepatitis_A_virus_genotype_IB R-HSA-111933 Calmodulin induced events 15/1200 36/10654 3.057509130481137e-6 1.2789716159368554e-5 6.109563293735725e-6 818/815/5567/817/5578/5582/10645/5566/84254/816/5613/5577/5580/801/814 15 Human_hepatitis_A_virus_genotype_IB R-HSA-111997 CaM pathway 15/1200 36/10654 3.057509130481137e-6 1.2789716159368554e-5 6.109563293735725e-6 818/815/5567/817/5578/5582/10645/5566/84254/816/5613/5577/5580/801/814 15 Human_hepatitis_A_virus_genotype_IB R-HSA-169893 Prolonged ERK activation events 9/1200 14/10654 3.349207793161756e-6 1.3868867170340963e-5 6.625066634300894e-6 5604/5594/673/10818/4914/4803/1398/7529/5595 9 Human_hepatitis_A_virus_genotype_IB R-HSA-399955 SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion 9/1200 14/10654 3.349207793161756e-6 1.3868867170340963e-5 6.625066634300894e-6 5361/10371/8829/55558/2534/91584/5362/5879/2242 9 Human_hepatitis_A_virus_genotype_IB R-HSA-9027284 Erythropoietin activates RAS 9/1200 14/10654 3.349207793161756e-6 1.3868867170340963e-5 6.625066634300894e-6 4893/6464/4067/3717/6654/2885/8660/3845/3265 9 Human_hepatitis_A_virus_genotype_IB R-HSA-5663205 Infectious disease 73/1200 383/10654 3.541758725433261e-6 1.461715808422958e-5 6.982520282494723e-6 3303/8945/81929/5434/1839/5684/8065/6194/6191/5606/5604/1499/1938/3159/6159/6147/6129/6217/5707/8106/6125/4869/821/6500/811/6224/9636/6232/7316/6175/920/292/4233/3055/51534/6714/6210/23327/867/5688/999/3320/5686/2534/5710/5901/6139/5609/6233/2885/3326/5716/7514/1025/9844/7311/3932/1213/5610/3921/6188/6189/6161/3304/6829/801/5608/1022/5062/5693/6122/7314/5879 73 Human_hepatitis_A_virus_genotype_IB R-HSA-69618 Mitotic Spindle Checkpoint 30/1200 112/10654 3.99577690248205e-6 1.643596232554283e-5 7.851351106631396e-6 11130/81929/54908/25936/80776/1783/7321/9212/79980/6232/332/1780/5048/1781/8655/22919/79003/11243/51143/7514/5518/54820/5347/29882/23332/9793/10726/140735/5515/1778 30 Human_hepatitis_A_virus_genotype_IB R-HSA-8853659 RET signaling 16/1200 41/10654 4.028902047727744e-6 1.6517159890020055e-5 7.89013864916082e-6 5295/6464/5290/5335/5291/5567/5578/6714/10818/5566/5598/5979/6654/2885/8660/2549 16 Human_hepatitis_A_virus_genotype_IB R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 20/1200 60/10654 4.600940766072586e-6 1.8799870547462155e-5 8.980574517255657e-6 8454/1147/8945/5684/5707/6500/7316/9020/5970/5688/23291/5686/5710/9040/6233/5716/7311/5693/4791/7314 20 Human_hepatitis_A_virus_genotype_IB R-HSA-5610787 Hedgehog 'off' state 30/1200 113/10654 4.864250786190008e-6 1.9810183069829934e-5 9.463194164552386e-6 8454/8945/5684/2735/54903/5707/5567/1452/10382/6500/7277/7316/5566/2932/5688/7846/347733/5686/5710/83737/5577/6233/5716/7311/10383/23432/23322/8481/5693/7314 30 Human_hepatitis_A_virus_genotype_IB R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 12/1200 25/10654 5.049666813843542e-6 2.0430455240271907e-5 9.75949410095732e-6 9252/5594/9261/5598/1432/6195/6196/5518/6197/51231/5595/5515 12 Human_hepatitis_A_virus_genotype_IB R-HSA-5654708 Downstream signaling of activated FGFR3 12/1200 25/10654 5.049666813843542e-6 2.0430455240271907e-5 9.75949410095732e-6 5295/4893/6464/5290/5335/10818/2261/6654/2885/3845/2549/3265 12 Human_hepatitis_A_virus_genotype_IB R-HSA-5654726 Negative regulation of FGFR1 signaling 14/1200 33/10654 5.067494514909229e-6 2.043558245554898e-5 9.761943337974435e-6 5594/2260/7316/673/6714/10818/867/6233/2885/7311/5518/7314/5595/5515 14 Human_hepatitis_A_virus_genotype_IB R-HSA-373760 L1CAM interactions 31/1200 119/10654 5.209585393807073e-6 2.094015757641019e-5 1.0002975554712708e-5 9252/79861/71/5604/1459/10382/5594/1460/7277/2260/8829/1457/6714/27330/7846/347733/3690/6195/6386/6709/3685/6196/1213/10383/1956/6197/3312/5058/8506/5879/5595 31 Human_hepatitis_A_virus_genotype_IB R-HSA-933541 TRAF6 mediated IRF7 activation 13/1200 29/10654 5.267913454878564e-6 2.110586104974074e-5 1.0082131014121653e-5 7186/29110/57506/7706/23586/1387/2033/64135/3661/7189/10010/84282/9641 13 Human_hepatitis_A_virus_genotype_IB R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 21/1200 66/10654 6.1729514871483535e-6 2.465185157003582e-5 1.1776027364343647e-5 5684/64344/112399/7321/5707/84962/3091/7316/7322/5688/5686/5710/7428/8453/6233/5716/7311/2034/54583/5693/7314 21 Human_hepatitis_A_virus_genotype_IB R-HSA-5655302 Signaling by FGFR1 in disease 15/1200 38/10654 6.828980083345648e-6 2.7183746525317838e-5 1.2985496932677631e-5 5295/4893/5290/5335/9530/613/2260/6774/10818/11064/6654/2885/3845/2549/3265 15 Human_hepatitis_A_virus_genotype_IB R-HSA-75153 Apoptotic execution phase 18/1200 52/10654 7.518766527553397e-6 2.9799805621016597e-5 1.4235171157356729e-5 4000/51765/1499/5747/841/7082/660/3146/10134/329/999/5588/836/4137/5580/6709/6093/5062 18 Human_hepatitis_A_virus_genotype_IB R-HSA-844456 The NLRP3 inflammasome 9/1200 15/10654 7.534472734000955e-6 2.9799805621016597e-5 1.4235171157356729e-5 351/4790/10910/29108/5970/3326/4210/114548/4791 9 Human_hepatitis_A_virus_genotype_IB R-HSA-198753 ERK/MAPK targets 11/1200 22/10654 7.673705150062703e-6 3.0061435413261506e-5 1.436014998842143e-5 9252/5594/5598/1432/6195/6196/5518/6197/51231/5595/5515 11 Human_hepatitis_A_virus_genotype_IB R-HSA-5655332 Signaling by FGFR3 in disease 11/1200 22/10654 7.673705150062703e-6 3.0061435413261506e-5 1.436014998842143e-5 5295/4893/5290/5335/10818/2261/6654/2885/3845/2549/3265 11 Human_hepatitis_A_virus_genotype_IB R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 11/1200 22/10654 7.673705150062703e-6 3.0061435413261506e-5 1.436014998842143e-5 5295/4893/5290/5335/10818/2261/6654/2885/3845/2549/3265 11 Human_hepatitis_A_virus_genotype_IB R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission 45/1200 206/10654 8.119662474384955e-6 3.17077958651615e-5 1.5146605548486256e-5 818/5170/5563/815/4893/79861/5579/5567/817/5578/10382/5594/51422/5582/7277/53632/10645/6714/5566/84254/5571/27330/7846/347733/3084/6195/4137/816/2066/5613/2771/5577/6196/5562/10383/6197/3845/3265/5564/801/5565/814/5879/5595/4193 45 Human_hepatitis_A_virus_genotype_IB R-HSA-111932 CaMK IV-mediated phosphorylation of CREB 8/1200 12/10654 8.264251192620653e-6 3.1968921541360145e-5 1.5271343566631135e-5 818/815/817/10645/84254/816/801/814 8 Human_hepatitis_A_virus_genotype_IB R-HSA-170968 Frs2-mediated activation 8/1200 12/10654 8.264251192620653e-6 3.1968921541360145e-5 1.5271343566631135e-5 5604/5594/673/10818/4914/4803/7529/5595 8 Human_hepatitis_A_virus_genotype_IB R-HSA-210990 PECAM1 interactions 8/1200 12/10654 8.264251192620653e-6 3.1968921541360145e-5 1.5271343566631135e-5 5335/6714/4067/2534/3690/7525/3685/3932 8 Human_hepatitis_A_virus_genotype_IB R-HSA-2173788 Downregulation of TGF-beta receptor signaling 12/1200 26/10654 8.419888511092993e-6 3.2469195070902354e-5 1.551032094148709e-5 10273/7316/23327/23645/7046/4087/5499/6233/7514/7048/7311/7314 12 Human_hepatitis_A_virus_genotype_IB R-HSA-8939902 Regulation of RUNX2 expression and activity 22/1200 73/10654 1.0026893862219057e-5 3.854575397501033e-5 1.8413053165576886e-5 8454/7291/5684/5707/10273/6500/7316/11059/2099/2932/5688/6502/2908/5686/55294/5710/6233/5716/7311/1750/5693/7314 22 Human_hepatitis_A_virus_genotype_IB R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 24/1200 84/10654 1.1099002929484786e-5 4.253468824529263e-5 2.0318540832008763e-5 6118/10445/7515/8450/54778/7316/10980/6119/4798/1642/10987/1069/6233/7311/8533/8607/6117/7334/1022/5886/50813/7314/51138/8451 24 Human_hepatitis_A_virus_genotype_IB R-HSA-6804760 Regulation of TP53 Activity through Methylation 10/1200 19/10654 1.123076490743619e-5 4.290638977020514e-5 2.0496100205847372e-5 7316/4194/56950/2033/7157/6233/7311/10419/7314/4193 10 Human_hepatitis_A_virus_genotype_IB R-HSA-109704 PI3K Cascade 16/1200 44/10654 1.1728043984010123e-5 4.466792060576695e-5 2.1337571900733167e-5 5295/5170/5290/3667/5291/2322/2260/5289/10818/2261/2264/208/2885/8660/2549/30849 16 Human_hepatitis_A_virus_genotype_IB R-HSA-199977 ER to Golgi Anterograde Transport 36/1200 154/10654 1.3577692281471124e-5 5.1354844920006705e-5 2.4531871666982642e-5 10113/11014/79861/11258/55291/1783/10382/93661/55860/830/7277/10671/1780/1781/8655/84516/1639/832/3998/10121/8775/55014/7846/347733/51143/3630/10540/6709/83696/5537/10383/1453/140735/829/51164/1778 36 Human_hepatitis_A_virus_genotype_IB R-HSA-5654716 Downstream signaling of activated FGFR4 12/1200 27/10654 1.3608617738121712e-5 5.1354844920006705e-5 2.4531871666982642e-5 5295/4893/6464/5290/5335/10818/2264/6654/2885/3845/2549/3265 12 Human_hepatitis_A_virus_genotype_IB R-HSA-912526 Interleukin receptor SHC signaling 12/1200 27/10654 1.3608617738121712e-5 5.1354844920006705e-5 2.4531871666982642e-5 5295/6464/5290/1437/5291/1439/1438/3558/3717/6654/2885/3716 12 Human_hepatitis_A_virus_genotype_IB R-HSA-112043 PLC beta mediated events 18/1200 54/10654 1.3705861358526047e-5 5.1564124745186406e-5 2.4631843263076332e-5 818/815/5567/817/5578/5594/5582/3708/10645/5566/84254/816/5613/2771/5577/5580/801/814 18 Human_hepatitis_A_virus_genotype_IB R-HSA-5676590 NIK-->noncanonical NF-kB signaling 19/1200 59/10654 1.3967097638629751e-5 5.2387229440939546e-5 2.5025034962830457e-5 8454/1147/8945/5684/5707/6500/7316/9020/5688/23291/5686/5710/9040/6233/5716/7311/5693/4791/7314 19 Human_hepatitis_A_virus_genotype_IB R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 27/1200 102/10654 1.5180553950053975e-5 5.676607143747456e-5 2.7116778985742345e-5 8454/7124/1147/8945/5684/7186/5707/356/6500/330/7316/9020/7132/5688/329/23291/5686/5710/9040/6233/5716/7311/7187/958/5693/4791/7314 27 Human_hepatitis_A_virus_genotype_IB R-HSA-205043 NRIF signals cell death from the nucleus 9/1200 16/10654 1.549891283196578e-5 5.760740492363185e-5 2.751867845878515e-5 4804/8878/7316/4803/7189/6233/7311/5599/7314 9 Human_hepatitis_A_virus_genotype_IB R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 9/1200 16/10654 1.549891283196578e-5 5.760740492363185e-5 2.751867845878515e-5 5295/5170/6464/5290/5291/4067/2534/6654/2885 9 Human_hepatitis_A_virus_genotype_IB R-HSA-376176 Signaling by ROBO receptors 46/1200 218/10654 1.6757496914457152e-5 6.209835192924963e-5 2.966397430724199e-5 25/23032/5684/6194/6191/6159/6147/6129/6217/5707/5567/56924/5578/6125/6224/6232/2935/8829/7316/6175/6714/6210/5566/5688/5686/5063/5710/8453/6139/10487/6654/6233/5716/7311/387/3921/6188/6189/6161/23332/5058/5062/5693/6122/7314/5879 46 Human_hepatitis_A_virus_genotype_IB R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 24/1200 86/10654 1.7178553853714082e-5 6.327861329994978e-5 3.0227777401664995e-5 8454/1017/8945/5684/7321/5707/9212/6500/7316/983/6790/5688/6502/5686/5710/4751/6233/5716/51343/7311/5347/29882/5693/7314 24 Human_hepatitis_A_virus_genotype_IB R-HSA-453276 Regulation of mitotic cell cycle 24/1200 86/10654 1.7178553853714082e-5 6.327861329994978e-5 3.0227777401664995e-5 8454/1017/8945/5684/7321/5707/9212/6500/7316/983/6790/5688/6502/5686/5710/4751/6233/5716/51343/7311/5347/29882/5693/7314 24 Human_hepatitis_A_virus_genotype_IB R-HSA-69481 G2/M Checkpoints 38/1200 168/10654 1.7673784308423862e-5 6.490907689462811e-5 3.100663913758572e-5 1017/4172/6118/5684/5883/7531/51512/5707/7532/2810/545/7534/7316/4174/983/641/4171/6119/3364/10524/5688/5686/995/5710/1111/7157/6233/5716/672/7311/9025/6117/7334/7465/5810/5693/7529/7314 38 Human_hepatitis_A_virus_genotype_IB R-HSA-112040 G-protein mediated events 18/1200 55/10654 1.8252744454789997e-5 6.683645892347434e-5 3.19273368567309e-5 818/815/5567/817/5578/5594/5582/3708/10645/5566/84254/816/5613/2771/5577/5580/801/814 18 Human_hepatitis_A_virus_genotype_IB R-HSA-877300 Interferon gamma signaling 25/1200 92/10654 1.9108253318080932e-5 6.976208459914755e-5 3.332488900070172e-5 818/815/6737/23321/4281/7412/817/3123/7706/3126/2634/51127/3115/3122/3659/3717/3458/816/3661/5580/3716/10107/3127/3125/3660 25 Human_hepatitis_A_virus_genotype_IB R-HSA-1251985 Nuclear signaling by ERBB4 13/1200 32/10654 1.9489622311046315e-5 7.052842795258403e-5 3.369096618054001e-5 1839/685/5241/2069/23118/10413/6714/2099/145957/3084/2066/9542/10718 13 Human_hepatitis_A_virus_genotype_IB R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 13/1200 32/10654 1.9489622311046315e-5 7.052842795258403e-5 3.369096618054001e-5 54778/7316/6667/4609/22938/1874/4087/6233/1025/1030/7311/23439/7314 13 Human_hepatitis_A_virus_genotype_IB R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 13/1200 32/10654 1.9489622311046315e-5 7.052842795258403e-5 3.369096618054001e-5 10694/79861/10575/10382/7277/10576/908/6950/7846/347733/10574/10383/22948 13 Human_hepatitis_A_virus_genotype_IB R-HSA-110056 MAPK3 (ERK1) activation 7/1200 10/10654 1.9947736027048734e-5 7.155670423656436e-5 3.4182166998614724e-5 5604/983/3717/3716/7297/3569/5595 7 Human_hepatitis_A_virus_genotype_IB R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 7/1200 10/10654 1.9947736027048734e-5 7.155670423656436e-5 3.4182166998614724e-5 5563/51422/53632/1432/5571/5564/5565 7 Human_hepatitis_A_virus_genotype_IB R-HSA-390450 Folding of actin by CCT/TriC 7/1200 10/10654 1.9947736027048734e-5 7.155670423656436e-5 3.4182166998614724e-5 10694/10575/10576/908/6950/10574/22948 7 Human_hepatitis_A_virus_genotype_IB R-HSA-8876384 Listeria monocytogenes entry into host cells 10/1200 20/10654 2.019753153176373e-5 7.224276495709114e-5 3.450989369271606e-5 1499/7316/4233/6714/867/999/6233/2885/7311/7314 10 Human_hepatitis_A_virus_genotype_IB R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 12/1200 28/10654 2.1385760921145706e-5 7.627176004824797e-5 3.643451814980711e-5 10694/10575/10382/7277/10576/908/6950/7846/347733/10574/10383/22948 12 Human_hepatitis_A_virus_genotype_IB R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 11/1200 24/10654 2.1921297087381072e-5 7.795642825887102e-5 3.723927307427089e-5 5590/5579/5578/5594/5289/6279/1432/5580/30849/5879/5595 11 Human_hepatitis_A_virus_genotype_IB R-HSA-1236975 Antigen processing-Cross presentation 26/1200 99/10654 2.5238777879552514e-5 8.949612615910288e-5 4.275171086675562e-5 23643/1147/8773/5684/5707/811/10333/7099/8517/4615/7316/7096/5688/929/5686/114609/5710/695/6233/5716/3685/7311/7097/3551/5693/7314 26 Human_hepatitis_A_virus_genotype_IB R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 24/1200 88/10654 2.6123238958000414e-5 9.236698244748571e-5 4.4123100034625946e-5 3303/5684/5707/207/5578/3315/7534/7316/9261/1432/5688/5686/5710/6233/5580/5716/7514/7311/3304/3312/5693/7529/7314/1994 24 Human_hepatitis_A_virus_genotype_IB R-HSA-5696398 Nucleotide Excision Repair 28/1200 111/10654 2.800107354220567e-5 9.872378500309085e-5 4.7159702807925335e-5 10450/6118/5434/27339/10445/7515/8450/54778/7316/10980/6119/4798/1642/2033/10987/1069/6233/7311/8533/8607/6117/7334/1022/5886/50813/7314/51138/8451 28 Human_hepatitis_A_virus_genotype_IB R-HSA-202433 Generation of second messenger molecules 13/1200 33/10654 2.8864005378535477e-5 1.0147630380943811e-4 4.847456293891098e-5 5335/3123/3126/3115/3122/920/5063/3702/3932/3127/3125/5058/5062 13 Human_hepatitis_A_virus_genotype_IB R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 12/1200 29/10654 3.2763065014981366e-5 1.14856881330929e-4 5.486637681934678e-5 2308/2309/4303/4287/6720/847/2908/3630/3066/4087/91584/25942 12 Human_hepatitis_A_virus_genotype_IB R-HSA-389513 CTLA4 inhibitory signaling 10/1200 21/10654 3.467632921332537e-5 1.2121980240578897e-4 5.7905902369053844e-5 207/6714/4067/10000/2534/208/7525/3932/5518/5515 10 Human_hepatitis_A_virus_genotype_IB R-HSA-5696395 Formation of Incision Complex in GG-NER 15/1200 43/10654 3.8786902207969985e-5 1.3520632012608747e-4 6.458716989730358e-5 6118/8450/54778/7316/6119/1642/1069/6233/7311/6117/7334/1022/5886/7314/8451 15 Human_hepatitis_A_virus_genotype_IB R-HSA-6806834 Signaling by MET 22/1200 79/10654 3.9524518273681577e-5 1.3738945225274103e-4 6.563003775615028e-5 5295/4893/6464/5290/5747/7316/6774/4233/6714/3910/867/2335/6654/6233/2885/1398/7311/3845/2549/3265/7314/5879 22 Human_hepatitis_A_virus_genotype_IB R-HSA-73893 DNA Damage Bypass 16/1200 48/10654 4.098875237227737e-5 1.3979623273384785e-4 6.677974096302549e-5 6118/9636/7706/8450/7316/9100/7415/6119/51455/1642/5429/6233/7311/6117/7314/8451 16 Human_hepatitis_A_virus_genotype_IB R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 18/1200 58/10654 4.10033506030119e-5 1.3979623273384785e-4 6.677974096302549e-5 8454/2648/55869/3280/6500/10013/7316/9759/4609/10014/22938/1387/2033/55294/3066/6233/7311/7314 18 Human_hepatitis_A_virus_genotype_IB R-HSA-2644603 Signaling by NOTCH1 in Cancer 18/1200 58/10654 4.10033506030119e-5 1.3979623273384785e-4 6.677974096302549e-5 8454/2648/55869/3280/6500/10013/7316/9759/4609/10014/22938/1387/2033/55294/3066/6233/7311/7314 18 Human_hepatitis_A_virus_genotype_IB R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 18/1200 58/10654 4.10033506030119e-5 1.3979623273384785e-4 6.677974096302549e-5 8454/2648/55869/3280/6500/10013/7316/9759/4609/10014/22938/1387/2033/55294/3066/6233/7311/7314 18 Human_hepatitis_A_virus_genotype_IB R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 18/1200 58/10654 4.10033506030119e-5 1.3979623273384785e-4 6.677974096302549e-5 8454/2648/55869/3280/6500/10013/7316/9759/4609/10014/22938/1387/2033/55294/3066/6233/7311/7314 18 Human_hepatitis_A_virus_genotype_IB R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 18/1200 58/10654 4.10033506030119e-5 1.3979623273384785e-4 6.677974096302549e-5 8454/2648/55869/3280/6500/10013/7316/9759/4609/10014/22938/1387/2033/55294/3066/6233/7311/7314 18 Human_hepatitis_A_virus_genotype_IB R-HSA-2559580 Oxidative Stress Induced Senescence 30/1200 125/10654 4.1009915923543695e-5 1.3979623273384785e-4 6.677974096302549e-5 3725/1019/5606/9448/1029/2146/6045/5594/50488/192670/7316/9261/7867/4194/1432/1021/192669/7157/5609/6233/1030/7311/5599/4217/26523/5608/7314/5595/4193/23043 30 Human_hepatitis_A_virus_genotype_IB R-HSA-5654727 Negative regulation of FGFR2 signaling 13/1200 34/10654 4.194882693751721e-5 1.4260289928621554e-4 6.81204671161654e-5 5594/7316/673/6714/10818/867/6233/2885/7311/5518/7314/5595/5515 13 Human_hepatitis_A_virus_genotype_IB R-HSA-73894 DNA Repair 62/1200 334/10654 4.403528513515579e-5 1.4928445565050066e-4 7.131220264802558e-5 10450/1017/7014/6118/2176/25/25913/5434/5893/151987/5888/5883/328/27339/10445/7515/7013/5531/9636/545/7706/5591/8450/54778/7316/641/9100/7415/10980/6119/51455/3364/10524/4798/1642/5429/2033/1111/10987/7157/1069/4255/6233/672/7311/6047/9025/2189/5536/8533/8607/6117/2175/5599/7334/5810/1022/5886/50813/7314/51138/8451 62 Human_hepatitis_A_virus_genotype_IB R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 7/1200 11/10654 4.9504980879156766e-5 1.6645543979531185e-4 7.951466884361906e-5 64344/7422/3091/1387/2033/2034/405 7 Human_hepatitis_A_virus_genotype_IB R-HSA-8851805 MET activates RAS signaling 7/1200 11/10654 4.9504980879156766e-5 1.6645543979531185e-4 7.951466884361906e-5 4893/6464/4233/6654/2885/3845/3265 7 Human_hepatitis_A_virus_genotype_IB R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 7/1200 11/10654 4.9504980879156766e-5 1.6645543979531185e-4 7.951466884361906e-5 4893/4915/10818/6654/2885/3845/3265 7 Human_hepatitis_A_virus_genotype_IB R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 15/1200 44/10654 5.278286335829442e-5 1.765150498215049e-4 8.432007839293932e-5 7321/54778/7316/6667/4609/22938/23327/1874/4087/6233/1025/1030/7311/23439/7314 15 Human_hepatitis_A_virus_genotype_IB R-HSA-451927 Interleukin-2 family signaling 15/1200 44/10654 5.278286335829442e-5 1.765150498215049e-4 8.432007839293932e-5 5295/6464/5290/1437/5291/1439/1438/6774/3558/3717/6654/2885/3716/3932/2185 15 Human_hepatitis_A_virus_genotype_IB R-HSA-111471 Apoptotic factor-mediated response 9/1200 18/10654 5.337207165971142e-5 1.7752327878189727e-4 8.480170273638357e-5 1029/842/5594/54205/836/331/317/578/5595 9 Human_hepatitis_A_virus_genotype_IB R-HSA-210993 Tie2 Signaling 9/1200 18/10654 5.337207165971142e-5 1.7752327878189727e-4 8.480170273638357e-5 5295/4893/6464/5290/5291/6654/2885/3845/3265 9 Human_hepatitis_A_virus_genotype_IB R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 17/1200 54/10654 5.4447163827164144e-5 1.8061236602881872e-4 8.627733939788318e-5 10450/5434/27339/8450/7316/10980/1642/2033/10987/6233/7311/8533/1022/50813/7314/51138/8451 17 Human_hepatitis_A_virus_genotype_IB R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 10/1200 22/10654 5.7178515932710854e-5 1.8865852583145772e-4 9.012093701750093e-5 4000/3725/351/2309/10018/7531/356/995/8851/1020 10 Human_hepatitis_A_virus_genotype_IB R-HSA-8863678 Neurodegenerative Diseases 10/1200 22/10654 5.7178515932710854e-5 1.8865852583145772e-4 9.012093701750093e-5 4000/3725/351/2309/10018/7531/356/995/8851/1020 10 Human_hepatitis_A_virus_genotype_IB R-HSA-114604 GPVI-mediated activation cascade 13/1200 35/10654 5.991060634189908e-5 1.971458352690759e-4 9.417526891638872e-5 5295/5170/5590/5290/5291/146850/4067/23533/5294/2534/3932/387/5879 13 Human_hepatitis_A_virus_genotype_IB R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 27/1200 110/10654 6.470076628727967e-5 2.123424085066572e-4 1.014345720069334e-4 1017/3725/1019/4790/1029/7321/5594/1027/3576/3490/7316/6774/5970/1026/5598/1021/6195/6233/1030/51343/6196/7311/6197/29882/3569/7314/5595 27 Human_hepatitis_A_virus_genotype_IB R-HSA-5610780 Degradation of GLI1 by the proteasome 18/1200 60/10654 6.768667362207819e-5 2.203835230861332e-4 1.0527575955662763e-4 8454/8945/5684/2735/5707/5567/6500/7316/5566/5688/5686/5710/83737/6233/5716/7311/5693/7314 18 Human_hepatitis_A_virus_genotype_IB R-HSA-5610783 Degradation of GLI2 by the proteasome 18/1200 60/10654 6.768667362207819e-5 2.203835230861332e-4 1.0527575955662763e-4 8454/8945/5684/5707/5567/1452/6500/7316/5566/2932/5688/5686/5710/6233/5716/7311/5693/7314 18 Human_hepatitis_A_virus_genotype_IB R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 18/1200 60/10654 6.768667362207819e-5 2.203835230861332e-4 1.0527575955662763e-4 8454/8945/5684/5707/5567/1452/6500/7316/5566/2932/5688/5686/5710/6233/5716/7311/5693/7314 18 Human_hepatitis_A_virus_genotype_IB R-HSA-156842 Eukaryotic Translation Elongation 24/1200 93/10654 6.937734972292958e-5 2.2529381462656607e-4 1.0762137353141431e-4 6194/6191/1938/6159/6147/6129/1915/6217/1936/6125/1937/6224/6232/6175/1933/6210/6139/6233/7311/3921/6188/6189/6161/6122 24 Human_hepatitis_A_virus_genotype_IB R-HSA-5654687 Downstream signaling of activated FGFR1 12/1200 31/10654 7.187530041651238e-5 2.3279296775321857e-4 1.1120366965947487e-4 5295/4893/6464/5290/5335/2260/10818/6654/2885/3845/2549/3265 12 Human_hepatitis_A_virus_genotype_IB R-HSA-9013694 Signaling by NOTCH4 22/1200 82/10654 7.341348444299043e-5 2.3715246021636173e-4 1.1328617053754379e-4 8454/5684/2648/5707/207/3280/6500/7534/7316/22938/5688/1387/5686/2033/55294/5710/6233/2324/5716/7311/5693/7314 22 Human_hepatitis_A_virus_genotype_IB R-HSA-354192 Integrin alphaIIb beta3 signaling 11/1200 27/10654 8.311887897108725e-5 2.6710598086021267e-4 1.2759477035035322e-4 5170/6464/5747/207/6714/2335/3690/6654/2885/1398/9564 11 Human_hepatitis_A_virus_genotype_IB R-HSA-9006921 Integrin signaling 11/1200 27/10654 8.311887897108725e-5 2.6710598086021267e-4 1.2759477035035322e-4 5170/6464/5747/207/6714/2335/3690/6654/2885/1398/9564 11 Human_hepatitis_A_virus_genotype_IB R-HSA-110320 Translesion Synthesis by POLH 9/1200 19/10654 9.129924773675949e-5 2.911195651347835e-4 1.3906590162541903e-4 6118/7316/7415/6119/5429/6233/7311/6117/7314 9 Human_hepatitis_A_virus_genotype_IB R-HSA-3928664 Ephrin signaling 9/1200 19/10654 9.129924773675949e-5 2.911195651347835e-4 1.3906590162541903e-4 2051/6714/2047/5063/2534/6386/5058/5062/5879 9 Human_hepatitis_A_virus_genotype_IB R-HSA-5686938 Regulation of TLR by endogenous ligand 9/1200 19/10654 9.129924773675949e-5 2.911195651347835e-4 1.3906590162541903e-4 23643/6271/10333/7099/7096/6279/3146/929/7097 9 Human_hepatitis_A_virus_genotype_IB R-HSA-202733 Cell surface interactions at the vascular wall 31/1200 137/10654 1.0138648894727021e-4 3.224508437137408e-4 1.5403264734257003e-4 5295/4893/6464/857/5290/5335/5291/483/10461/482/2994/6714/8797/4067/682/2335/2534/3690/23759/6654/4099/2885/7525/3685/3932/3845/4282/3265/8795/481/5669 31 Human_hepatitis_A_virus_genotype_IB R-HSA-5656169 Termination of translesion DNA synthesis 12/1200 32/10654 1.0330670727979166e-4 3.277133079261257e-4 1.5654649188657374e-4 6118/9636/7706/7316/9100/6119/51455/5429/6233/7311/6117/7314 12 Human_hepatitis_A_virus_genotype_IB R-HSA-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation 7/1200 12/10654 1.0724200244030711e-4 3.3673443005429767e-4 1.6085582259695185e-4 6697/2643/207/3320/4846/5593/801 7 Human_hepatitis_A_virus_genotype_IB R-HSA-389359 CD28 dependent Vav1 pathway 7/1200 12/10654 1.0724200244030711e-4 3.3673443005429767e-4 1.6085582259695185e-4 5063/2534/2885/3932/5058/5062/5879 7 Human_hepatitis_A_virus_genotype_IB R-HSA-5689877 Josephin domain DUBs 7/1200 12/10654 1.0724200244030711e-4 3.3673443005429767e-4 1.6085582259695185e-4 4287/7316/7415/6233/7311/5886/7314 7 Human_hepatitis_A_virus_genotype_IB R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 7/1200 12/10654 1.0724200244030711e-4 3.3673443005429767e-4 1.6085582259695185e-4 355/8797/7157/8626/7161/7159/8795 7 Human_hepatitis_A_virus_genotype_IB R-HSA-176187 Activation of ATR in response to replication stress 13/1200 37/10654 1.1653408945748781e-4 3.640583959254176e-4 1.7390830138892252e-4 1017/4172/6118/5883/545/4174/4171/6119/3364/995/1111/6117/5810 13 Human_hepatitis_A_virus_genotype_IB R-HSA-5685938 HDR through Single Strand Annealing (SSA) 13/1200 37/10654 1.1653408945748781e-4 3.640583959254176e-4 1.7390830138892252e-4 6118/25/5893/5888/5883/545/641/6119/3364/10524/672/6117/5810 13 Human_hepatitis_A_virus_genotype_IB R-HSA-383280 Nuclear Receptor transcription pathway 16/1200 52/10654 1.21791045664765e-4 3.7952058169272735e-4 1.81294485838034e-4 5241/7182/5468/5465/2100/4306/9970/8856/2099/5467/2908/3164/2103/29982/367/10062 16 Human_hepatitis_A_virus_genotype_IB R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 21/1200 79/10654 1.2279766492131284e-4 3.8169349751360215e-4 1.82332473434801e-4 10450/6118/5434/27339/7515/8450/7316/10980/6119/1642/2033/10987/6233/7311/8533/6117/1022/50813/7314/51138/8451 21 Human_hepatitis_A_virus_genotype_IB R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 14/1200 42/10654 1.2323772712691998e-4 3.8209888259954584e-4 1.8252612322421368e-4 10694/6000/1459/10575/1460/10576/908/8786/1457/6950/2771/10574/22948/9628 14 Human_hepatitis_A_virus_genotype_IB R-HSA-69615 G1/S DNA Damage Checkpoints 19/1200 68/10654 1.2450724398459587e-4 3.8425308612227e-4 1.8355517207922138e-4 1017/5684/1029/5707/1027/7316/1026/4194/5688/5686/5710/1111/7157/6233/5716/7311/5693/7314/4193 19 Human_hepatitis_A_virus_genotype_IB R-HSA-437239 Recycling pathway of L1 15/1200 47/10654 1.2455529533947164e-4 3.8425308612227e-4 1.8355517207922138e-4 9252/79861/71/10382/5594/7277/6714/27330/7846/347733/6195/6196/1213/10383/6197 15 Human_hepatitis_A_virus_genotype_IB R-HSA-1226099 Signaling by FGFR in disease 18/1200 63/10654 1.363549054043118e-4 4.196058685010492e-4 2.0044296371286152e-4 5295/5434/4893/5290/5335/9530/613/2260/6774/10818/2261/11064/2264/6654/2885/3845/2549/3265 18 Human_hepatitis_A_virus_genotype_IB R-HSA-8940973 RUNX2 regulates osteoblast differentiation 10/1200 24/10654 1.4033664690039116e-4 4.307846325250813e-4 2.0578298576648087e-4 25/5594/3280/5925/10013/10413/6714/7525/367/5595 10 Human_hepatitis_A_virus_genotype_IB R-HSA-110312 Translesion synthesis by REV1 8/1200 16/10654 1.4174063364651892e-4 4.329404502965454e-4 2.0681280573749502e-4 6118/7316/6119/51455/6233/7311/6117/7314 8 Human_hepatitis_A_virus_genotype_IB R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 8/1200 16/10654 1.4174063364651892e-4 4.329404502965454e-4 2.0681280573749502e-4 5590/7316/7046/6233/7048/7311/387/7314 8 Human_hepatitis_A_virus_genotype_IB R-HSA-2172127 DAP12 interactions 14/1200 43/10654 1.6400709088089675e-4 4.997154324617941e-4 2.3871077555114273e-4 5295/4893/6464/5290/5335/5291/2534/695/6654/2885/3932/3845/3265/5879 14 Human_hepatitis_A_virus_genotype_IB R-HSA-9604323 Negative regulation of NOTCH4 signaling 16/1200 54/10654 1.994114768361847e-4 6.060930108764825e-4 2.8952664513420644e-4 8454/5684/5707/207/6500/7534/7316/5688/5686/55294/5710/6233/5716/7311/5693/7314 16 Human_hepatitis_A_virus_genotype_IB R-HSA-111461 Cytochrome c-mediated apoptotic response 7/1200 13/10654 2.0977106027366766e-4 6.32903394566518e-4 3.0233378909600794e-4 842/5594/54205/836/331/317/5595 7 Human_hepatitis_A_virus_genotype_IB R-HSA-171007 p38MAPK events 7/1200 13/10654 2.0977106027366766e-4 6.32903394566518e-4 3.0233378909600794e-4 4893/9261/6714/7867/1432/3845/3265 7 Human_hepatitis_A_virus_genotype_IB R-HSA-879415 Advanced glycosylation endproduct receptor signaling 7/1200 13/10654 2.0977106027366766e-4 6.32903394566518e-4 3.0233378909600794e-4 351/1650/5594/830/3146/829/5595 7 Human_hepatitis_A_virus_genotype_IB R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 10/1200 25/10654 2.104426928229265e-4 6.333811779109544e-4 3.0256202305735256e-4 1017/2305/983/995/7514/5518/5347/7465/1022/5515 10 Human_hepatitis_A_virus_genotype_IB R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 13/1200 39/10654 2.1424889887914473e-4 6.432679834960209e-4 3.0728488506164947e-4 6118/9636/7706/7316/9100/7415/6119/51455/5429/6233/7311/6117/7314 13 Human_hepatitis_A_virus_genotype_IB R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 14/1200 44/10654 2.1591173039144432e-4 6.466870759782579e-4 3.08918163053676e-4 355/332/8797/1387/843/7157/8626/604/7161/7159/317/10397/8795/665 14 Human_hepatitis_A_virus_genotype_IB R-HSA-5655862 Translesion synthesis by POLK 8/1200 17/10654 2.413816935628991e-4 7.177470117026927e-4 3.4286302700120097e-4 6118/7316/6119/51455/6233/7311/6117/7314 8 Human_hepatitis_A_virus_genotype_IB R-HSA-5656121 Translesion synthesis by POLI 8/1200 17/10654 2.413816935628991e-4 7.177470117026927e-4 3.4286302700120097e-4 6118/7316/6119/51455/6233/7311/6117/7314 8 Human_hepatitis_A_virus_genotype_IB R-HSA-8934593 Regulation of RUNX1 Expression and Activity 8/1200 17/10654 2.413816935628991e-4 7.177470117026927e-4 3.4286302700120097e-4 27161/894/192670/6714/1021/595/192669/26523 8 Human_hepatitis_A_virus_genotype_IB R-HSA-3928663 EPHA-mediated growth cone collapse 11/1200 30/10654 2.53049957953948e-4 7.488336885255918e-4 3.5771292806818344e-4 4627/2041/6714/4067/2043/2534/9475/7525/6093/387/1969 11 Human_hepatitis_A_virus_genotype_IB R-HSA-5654696 Downstream signaling of activated FGFR2 11/1200 30/10654 2.53049957953948e-4 7.488336885255918e-4 3.5771292806818344e-4 5295/4893/6464/5290/5335/10818/6654/2885/3845/2549/3265 11 Human_hepatitis_A_virus_genotype_IB R-HSA-69563 p53-Dependent G1 DNA Damage Response 18/1200 66/10654 2.598129257177934e-4 7.651769697750764e-4 3.655200060343281e-4 1017/5684/1029/5707/1027/7316/1026/4194/5688/5686/5710/7157/6233/5716/7311/5693/7314/4193 18 Human_hepatitis_A_virus_genotype_IB R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 18/1200 66/10654 2.598129257177934e-4 7.651769697750764e-4 3.655200060343281e-4 1017/5684/1029/5707/1027/7316/1026/4194/5688/5686/5710/7157/6233/5716/7311/5693/7314/4193 18 Human_hepatitis_A_virus_genotype_IB R-HSA-1169408 ISG15 antiviral mechanism 19/1200 72/10654 2.820968588114433e-4 8.268615342300816e-4 3.949863167865271e-4 81929/5335/9636/11274/7706/7316/4734/3434/23586/3661/51191/6233/3716/7311/5610/7334/5495/7314/5595 19 Human_hepatitis_A_virus_genotype_IB R-HSA-442729 CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde 6/1200 10/10654 2.8343794892976055e-4 8.268615342300816e-4 3.949863167865271e-4 818/10645/84254/816/801/814 6 Human_hepatitis_A_virus_genotype_IB R-HSA-450341 Activation of the AP-1 family of transcription factors 6/1200 10/10654 2.8343794892976055e-4 8.268615342300816e-4 3.949863167865271e-4 3725/5594/1432/1386/5599/5595 6 Human_hepatitis_A_virus_genotype_IB R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 6/1200 10/10654 2.8343794892976055e-4 8.268615342300816e-4 3.949863167865271e-4 2308/2309/4303/1387/2033/23411 6 Human_hepatitis_A_virus_genotype_IB R-HSA-182971 EGFR downregulation 11/1200 31/10654 3.526960195995386e-4 0.0010264785098722422 4.903420332069057e-4 1839/685/2069/7316/1950/867/6233/2885/7311/1956/7314 11 Human_hepatitis_A_virus_genotype_IB R-HSA-8854214 TBC/RABGAPs 14/1200 46/10654 3.630801925228447e-4 0.0010542140178192714 5.035911029419022e-4 5868/9363/11337/51256/7249/8766/8408/81631/10133/11345/338382/4218/7248/7879 14 Human_hepatitis_A_virus_genotype_IB R-HSA-111885 Opioid Signalling 22/1200 91/10654 3.7615992924586866e-4 0.0010896275884727743 5.205079327345848e-4 818/815/5567/817/5578/5594/5582/3708/10645/5566/84254/816/5613/5499/2771/5577/5580/5518/801/1020/814/5515 22 Human_hepatitis_A_virus_genotype_IB R-HSA-195721 Signaling by WNT 58/1200 331/10654 3.786557945522604e-4 0.0010897011243606145 5.20543060344574e-4 8454/27161/8945/815/5684/857/7015/7090/6885/5579/1499/1459/5707/207/1454/1452/5578/5582/6500/79577/1460/3708/192670/7534/8452/7316/1457/8658/4609/2932/10524/5688/1387/51339/5686/2033/5710/192669/208/23513/6233/5716/7514/7311/5518/1213/387/331/8607/5593/3845/26523/801/5693/4920/7314/5879/5515 58 Human_hepatitis_A_virus_genotype_IB R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 7/1200 14/10654 3.788345075775556e-4 0.0010897011243606145 5.20543060344574e-4 332/7157/8626/604/7161/7159/10397 7 Human_hepatitis_A_virus_genotype_IB R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 7/1200 14/10654 3.788345075775556e-4 0.0010897011243606145 5.20543060344574e-4 207/10000/7157/8626/208/7161/7159 7 Human_hepatitis_A_virus_genotype_IB R-HSA-447115 Interleukin-12 family signaling 16/1200 57/10654 3.950541100576103e-4 0.001133713422816491 5.4156744585621e-4 1072/9049/821/3313/6175/6774/6647/6950/3717/3458/3716/4282/7297/5062/5034/829 16 Human_hepatitis_A_virus_genotype_IB R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 20/1200 80/10654 4.287013683376792e-4 0.0012245775197423522 5.849726273613556e-4 81929/5335/2316/9636/11274/7706/7316/4734/3434/23586/3661/51191/6233/3716/7311/5610/7334/5495/7314/5595 20 Human_hepatitis_A_virus_genotype_IB R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 20/1200 80/10654 4.287013683376792e-4 0.0012245775197423522 5.849726273613556e-4 8454/1017/8945/5684/7321/5707/6500/7316/983/5688/5686/5710/6233/5716/51343/7311/5347/29882/5693/7314 20 Human_hepatitis_A_virus_genotype_IB R-HSA-162909 Host Interactions of HIV factors 28/1200 129/10654 4.4649844882680085e-4 0.0012724690204440467 6.078500822730242e-4 8945/81929/5684/8065/3159/5707/4869/6500/7316/920/292/3055/5688/5686/2534/5710/5901/6233/5716/7514/1025/9844/7311/3932/5062/5693/7314/5879 28 Human_hepatitis_A_virus_genotype_IB R-HSA-9020591 Interleukin-12 signaling 14/1200 47/10654 4.6427257314609244e-4 0.0013200745512955716 6.305909312680372e-4 1072/9049/3313/6175/6647/6950/3717/3458/3716/4282/7297/5062/5034/829 14 Human_hepatitis_A_virus_genotype_IB R-HSA-168254 Influenza Infection 32/1200 155/10654 4.669874985836372e-4 0.001324741547706226 6.328203247594358e-4 3303/81929/5434/6194/6191/6159/6147/6129/6217/8106/6125/821/811/6224/9636/6232/6175/6210/3320/5901/6139/6233/7514/7311/1213/5610/3921/6188/6189/6161/3304/6122 32 Human_hepatitis_A_virus_genotype_IB R-HSA-5626467 RHO GTPases activate IQGAPs 11/1200 32/10654 4.8332851652892883e-4 0.001364822401365442 6.519666849480914e-4 79861/71/1499/10382/7277/7846/999/347733/10383/801/5879 11 Human_hepatitis_A_virus_genotype_IB R-HSA-8941326 RUNX2 regulates bone development 11/1200 32/10654 4.8332851652892883e-4 0.001364822401365442 6.519666849480914e-4 25/5594/3280/5925/10013/9759/10413/6714/7525/367/5595 11 Human_hepatitis_A_virus_genotype_IB R-HSA-186797 Signaling by PDGF 16/1200 58/10654 4.894298415965365e-4 0.001378895946415813 6.586895248595539e-4 5295/4893/5290/5335/5291/6778/6774/6714/5159/6654/2885/1398/9564/3845/3265/5156 16 Human_hepatitis_A_virus_genotype_IB R-HSA-112409 RAF-independent MAPK1/3 activation 9/1200 23/10654 5.31408890895219e-4 0.0014937552878466975 7.1355707685247e-4 5604/5594/983/3717/3716/1843/7297/3569/5595 9 Human_hepatitis_A_virus_genotype_IB R-HSA-1059683 Interleukin-6 signaling 6/1200 11/10654 5.641575105904847e-4 0.0015750460816032989 7.523891543955024e-4 6774/867/3717/3716/7297/3569 6 Human_hepatitis_A_virus_genotype_IB R-HSA-111458 Formation of apoptosome 6/1200 11/10654 5.641575105904847e-4 0.0015750460816032989 7.523891543955024e-4 842/5594/54205/331/317/5595 6 Human_hepatitis_A_virus_genotype_IB R-HSA-9627069 Regulation of the apoptosome activity 6/1200 11/10654 5.641575105904847e-4 0.0015750460816032989 7.523891543955024e-4 842/5594/54205/331/317/5595 6 Human_hepatitis_A_virus_genotype_IB R-HSA-195253 Degradation of beta-catenin by the destruction complex 20/1200 82/10654 6.046489248224405e-4 0.0016842816551487392 8.045702694560215e-4 8454/8945/5684/7090/1499/5707/1452/6500/7316/2932/5688/5686/5710/6233/5716/7311/5518/5693/7314/5515 20 Human_hepatitis_A_virus_genotype_IB R-HSA-202430 Translocation of ZAP-70 to Immunological synapse 8/1200 19/10654 6.10327677157226e-4 0.0016962710666937318 8.102975324989249e-4 3123/3126/3115/3122/920/3932/3127/3125 8 Human_hepatitis_A_virus_genotype_IB R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 7/1200 15/10654 6.415224001235783e-4 0.0017789632398932487 8.49799039785225e-4 7316/4233/867/6233/2885/7311/7314 7 Human_hepatitis_A_virus_genotype_IB R-HSA-68949 Orc1 removal from chromatin 18/1200 71/10654 6.82880101583301e-4 0.001889403689134066 9.025557160411814e-4 8454/1017/4172/5684/5707/6500/7316/4174/4171/5688/6502/5686/5710/6233/5716/7311/5693/7314 18 Human_hepatitis_A_virus_genotype_IB R-HSA-948021 Transport to the Golgi and subsequent modification 36/1200 185/10654 6.935259876456696e-4 0.0019145661493394997 9.145756577924761e-4 10113/11014/79861/11258/55291/1783/10382/93661/55860/830/7277/10671/1780/1781/8655/84516/1639/832/3998/10121/8775/55014/7846/347733/51143/3630/10540/6709/83696/5537/10383/1453/140735/829/51164/1778 36 Human_hepatitis_A_virus_genotype_IB R-HSA-69473 G2/M DNA damage checkpoint 22/1200 95/10654 7.084490220309841e-4 0.001951397529433559 9.321697658302423e-4 6118/5883/7531/7532/2810/545/7534/983/641/6119/3364/10524/995/1111/7157/672/9025/6117/7334/7465/5810/7529 22 Human_hepatitis_A_virus_genotype_IB R-HSA-156902 Peptide chain elongation 21/1200 89/10654 7.149688497264054e-4 0.001964970068067671 9.386532782716846e-4 6194/6191/1938/6159/6147/6129/1915/6217/6125/6224/6232/6175/6210/6139/6233/7311/3921/6188/6189/6161/6122 21 Human_hepatitis_A_virus_genotype_IB R-HSA-8856688 Golgi-to-ER retrograde transport 28/1200 133/10654 7.466171884931977e-4 0.0020473902457791245 9.780248551022003e-4 11014/79861/11258/1783/10382/93661/55860/830/7277/10671/1780/5048/1781/8655/84516/1639/832/10121/8775/7846/347733/51143/10540/10383/140735/829/51164/1778 28 Human_hepatitis_A_virus_genotype_IB R-HSA-3858494 Beta-catenin independent WNT signaling 30/1200 146/10654 7.515240462952389e-4 0.002056276437091629 9.822697302493493e-4 27161/815/5684/6885/5579/1499/5707/5578/5582/3708/192670/7316/5688/5686/5710/192669/23513/6233/5716/7311/1213/387/5593/3845/26523/801/5693/4920/7314/5879 30 Human_hepatitis_A_virus_genotype_IB R-HSA-5627123 RHO GTPases activate PAKs 9/1200 24/10654 7.660522372921139e-4 0.0020913904000408596 9.990434394121653e-4 3984/4627/2316/4771/5063/5058/801/5062/5879 9 Human_hepatitis_A_virus_genotype_IB R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 18/1200 72/10654 8.164745158405845e-4 0.0022241270475657424 0.0010624508629504526 5684/7321/5707/9212/7316/6790/5688/6502/5686/5710/6233/5716/51343/7311/5347/29882/5693/7314 18 Human_hepatitis_A_virus_genotype_IB R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 15/1200 55/10654 8.293817880142877e-4 0.002249356321779409 0.0010745027213140568 8454/8945/5684/5707/6500/7316/5688/5686/5710/6233/5716/51343/7311/5693/7314 15 Human_hepatitis_A_virus_genotype_IB R-HSA-8941858 Regulation of RUNX3 expression and activity 15/1200 55/10654 8.293817880142877e-4 0.002249356321779409 0.0010745027213140568 5684/1029/5707/7316/6714/5688/5686/2033/5710/6233/5716/7311/5693/7314/4193 15 Human_hepatitis_A_virus_genotype_IB R-HSA-69052 Switching of origins to a post-replicative state 21/1200 90/10654 8.35652860726765e-4 0.002261393925738658 0.0010802530055562982 8454/1017/4172/5684/7321/5707/6500/7316/4174/4171/5688/6502/5686/5710/6233/5716/51343/7311/29882/5693/7314 21 Human_hepatitis_A_virus_genotype_IB R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 12/1200 39/10654 8.469616140438645e-4 0.0022869816886873715 0.0010924761116309206 6118/5888/5883/545/641/6119/3364/10524/1111/672/6117/5810 12 Human_hepatitis_A_virus_genotype_IB R-HSA-157118 Signaling by NOTCH 43/1200 235/10654 8.51593801960538e-4 0.00229446888999848 0.0010960526984553007 8454/27161/3725/5684/7090/5584/2648/55869/5707/207/3280/23220/6500/3091/10013/192670/7534/7316/1950/9759/4609/10014/22938/5688/1387/5686/2033/408/595/55294/5710/192669/3066/7157/83737/6233/2324/5716/7311/1956/26523/5693/7314 43 Human_hepatitis_A_virus_genotype_IB R-HSA-927802 Nonsense-Mediated Decay (NMD) 25/1200 115/10654 8.622853918088436e-4 0.0023131742902002457 0.0011049881451097308 6194/6191/6159/6147/6129/6217/6125/6224/6232/2935/6175/6210/6139/6233/23381/7311/5518/3921/6188/6189/23293/23049/6161/6122/5515 25 Human_hepatitis_A_virus_genotype_IB R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 25/1200 115/10654 8.622853918088436e-4 0.0023131742902002457 0.0011049881451097308 6194/6191/6159/6147/6129/6217/6125/6224/6232/2935/6175/6210/6139/6233/23381/7311/5518/3921/6188/6189/23293/23049/6161/6122/5515 25 Human_hepatitis_A_virus_genotype_IB R-HSA-8943724 Regulation of PTEN gene transcription 16/1200 61/10654 8.966808734868624e-4 0.002400226025776113 0.0011465721866711794 3725/5468/1822/2146/6045/5594/10014/6009/6615/3066/7157/1107/2475/1386/57521/5595 16 Human_hepatitis_A_virus_genotype_IB R-HSA-5627117 RHO GTPases Activate ROCKs 8/1200 20/10654 9.175638758105687e-4 0.002450809140152039 0.0011707354077327829 1072/3984/4627/3985/9475/6093/387/5058 8 Human_hepatitis_A_virus_genotype_IB R-HSA-5685942 HDR through Homologous Recombination (HRR) 17/1200 67/10654 9.433758103477976e-4 0.002514310475095426 0.0012010695777987192 6118/5888/5883/545/7316/641/6119/3364/10524/5429/1111/6233/672/7311/6117/5810/7314 17 Human_hepatitis_A_virus_genotype_IB R-HSA-112315 Transmission across Chemical Synapses 48/1200 272/10654 0.001000859881422942 0.002661769598439462 0.001271509831208819 818/5170/5563/815/4893/79861/5579/5567/817/5578/10382/5594/51422/5582/7277/53632/10645/6714/5566/84254/5571/27330/7846/347733/3084/6195/4137/816/1103/2066/5613/2771/10550/5577/6196/5562/10383/6197/3845/3265/3312/5564/801/5565/814/5879/5595/4193 48 Human_hepatitis_A_virus_genotype_IB R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 15/1200 56/10654 0.0010169237427314873 0.0026986750506035597 0.0012891393229872844 3303/5684/5707/3315/7316/5688/5686/5710/6233/5716/7311/3304/3312/5693/7314 15 Human_hepatitis_A_virus_genotype_IB R-HSA-2029481 FCGR activation 6/1200 12/10654 0.0010210730187406609 0.0027038714702274152 0.0012916216184657107 2268/3055/6714/4067/2534/7525 6 Human_hepatitis_A_virus_genotype_IB R-HSA-1834941 STING mediated induction of host immune responses 7/1200 16/10654 0.0010302415518279606 0.0027223085116824483 0.0013004288719117726 6737/29110/23220/147945/6778/5591/3661 7 Human_hepatitis_A_virus_genotype_IB R-HSA-400685 Sema4D in semaphorin signaling 9/1200 25/10654 0.001078582606056035 0.0028439549911819383 0.001358538595122311 3984/4627/3985/2064/4233/9475/6093/387/5879 9 Human_hepatitis_A_virus_genotype_IB R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 10/1200 30/10654 0.0011426632007461703 0.0029937290652245732 0.0014300846852561297 6118/8450/7316/6119/1642/6233/7311/6117/7314/8451 10 Human_hepatitis_A_virus_genotype_IB R-HSA-4090294 SUMOylation of intracellular receptors 10/1200 30/10654 0.0011426632007461703 0.0029937290652245732 0.0014300846852561297 5241/5468/5465/4306/9759/8856/2099/2908/367/10062 10 Human_hepatitis_A_virus_genotype_IB R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 10/1200 30/10654 0.0011426632007461703 0.0029937290652245732 0.0014300846852561297 7319/7321/7316/7317/7322/7347/6233/7311/997/7314 10 Human_hepatitis_A_virus_genotype_IB R-HSA-9018519 Estrogen-dependent gene expression 30/1200 150/10654 0.0011888418596878963 0.0031081162179128477 0.0014847266757921987 27161/3725/596/5434/7090/5241/8204/2625/192670/5885/6667/2099/4609/10524/1387/3320/2033/8243/9126/595/192669/2066/3326/1025/1386/3169/26523/8202/2288/10728 30 Human_hepatitis_A_virus_genotype_IB R-HSA-69541 Stabilization of p53 15/1200 57/10654 0.0012390200401150113 0.003232453973577006 0.0015441220039265748 5684/1029/5707/7316/4194/5688/5686/5710/7157/6233/5716/7311/5693/7314/4193 15 Human_hepatitis_A_virus_genotype_IB R-HSA-168255 Influenza Life Cycle 29/1200 144/10654 0.00127218714583951 0.003311980881784716 0.0015821114849436499 3303/81929/5434/6194/6191/6159/6147/6129/6217/6125/821/811/6224/6232/6175/6210/3320/5901/6139/6233/7514/7311/1213/3921/6188/6189/6161/3304/6122 29 Human_hepatitis_A_virus_genotype_IB R-HSA-180534 Vpu mediated degradation of CD4 14/1200 52/10654 0.0014041126161215974 0.003640073462802629 0.0017388391530917613 8945/5684/5707/6500/7316/920/5688/5686/5710/6233/5716/7311/5693/7314 14 Human_hepatitis_A_virus_genotype_IB R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 14/1200 52/10654 0.0014041126161215974 0.003640073462802629 0.0017388391530917613 1019/5684/5707/7316/2932/5688/5686/595/5710/6233/5716/7311/5693/7314 14 Human_hepatitis_A_virus_genotype_IB R-HSA-202131 Metabolism of nitric oxide: eNOS activation and regulation 7/1200 17/10654 0.0015824434526135027 0.004085220126621469 0.001951482786750851 6697/857/207/3320/4846/8976/801 7 Human_hepatitis_A_virus_genotype_IB R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 7/1200 17/10654 0.0015824434526135027 0.004085220126621469 0.001951482786750851 2308/857/2309/4303/1027/1026/4087 7 Human_hepatitis_A_virus_genotype_IB R-HSA-202670 ERKs are inactivated 6/1200 13/10654 0.0017164746974266526 0.004412770367967686 0.0021079513828046606 5594/5598/5518/51231/5595/5515 6 Human_hepatitis_A_virus_genotype_IB R-HSA-203615 eNOS activation 6/1200 13/10654 0.0017164746974266526 0.004412770367967686 0.0021079513828046606 6697/857/207/3320/4846/801 6 Human_hepatitis_A_virus_genotype_IB R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 12/1200 42/10654 0.0017407707156610994 0.004456661956692524 0.0021289181060716654 8945/7090/1499/207/7534/7316/208/6233/7514/7311/331/7314 12 Human_hepatitis_A_virus_genotype_IB R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 12/1200 42/10654 0.0017407707156610994 0.004456661956692524 0.0021289181060716654 6118/5888/5883/545/641/6119/3364/10524/1111/672/6117/5810 12 Human_hepatitis_A_virus_genotype_IB R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 16/1200 65/10654 0.0018589946476675505 0.0047494811495274476 0.002268795908671305 10450/6118/5434/27339/7515/8450/7316/6119/1642/2033/6233/7311/6117/1022/7314/8451 16 Human_hepatitis_A_virus_genotype_IB R-HSA-202427 Phosphorylation of CD3 and TCR zeta chains 8/1200 22/10654 0.001896210511597773 0.0048245850954879415 0.002304672569711889 3123/3126/3115/3122/920/3932/3127/3125 8 Human_hepatitis_A_virus_genotype_IB R-HSA-442982 Ras activation upon Ca2+ influx through NMDA receptor 8/1200 22/10654 0.001896210511597773 0.0048245850954879415 0.002304672569711889 818/815/4893/817/816/3845/3265/801 8 Human_herpesvirus_1 R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 302/6371 309/10654 2.0500731071719e-58 2.894703227326723e-55 1.1135133929481058e-55 8454/5689/127544/11065/221687/9666/84937/55070/5682/55819/93611/8916/7321/51665/65264/122769/9021/8697/26235/9817/9039/154881/7174/6478/143471/5705/57674/9690/8452/5709/9978/5695/23304/55236/54620/4734/7337/84676/7704/3093/10489/5711/23327/51465/10616/5683/89910/25898/5699/7328/7428/5702/22954/401036/83737/51529/140461/10075/29945/79176/8924/90135/56658/51434/6468/10425/25793/23295/51666/90293/54461/29882/7334/92591/55182/84961/4591/7332/5696/5691/9820/55658/7314/996/10324/283807/9354/5718/197131/8945/51088/64410/146330/51320/5700/122706/5707/10477/148581/92912/23198/10533/140462/51130/6477/7323/10517/9604/64718/4008/84861/11059/84085/27252/51444/26118/51433/9861/26249/55905/143279/6502/5698/27246/5692/5713/9903/201456/26190/79654/5710/9040/7324/5719/64682/8925/51191/6233/26091/6047/131405/868/136371/127247/5930/11275/29116/26268/115290/51725/140459/23608/55585/64320/51132/899/23352/26224/10293/114088/285231/142678/246184/142686/387522/151636/11146/255488/9616/91694/10193/140739/150726/390594/81559/144699/5706/200845/79876/26263/8881/7326/6049/57630/89890/22888/7317/80196/140456/55958/84078/5714/26272/8651/64219/140458/5688/55336/26270/5687/63893/89122/118424/5708/55008/10422/84727/90933/63891/9246/10393/5704/9870/9520/4012/25847/7327/51343/7311/7318/55175/9320/26232/57520/5694/92369/997/84261/7325/140691/57154/140460/5684/79754/6737/8065/5720/57531/84708/7319/54850/79791/26046/991/84231/10273/7320/5690/223082/5717/25897/9491/6500/26259/10197/53339/154214/7336/64750/51619/23376/54778/142689/7316/10213/114907/54926/7335/222235/25831/7322/5715/9867/5701/23291/5685/5686/55521/55294/135892/8453/80176/8139/126433/26267/142685/5716/90025/7064/84541/23194/55284/80204/26234/27338/23014/90678/5693/5721/51676/57542/642 302 Human_herpesvirus_1 R-HSA-983169 Class I MHC mediated antigen processing & presentation 353/6371 371/10654 6.949409875837607e-58 4.906283372341351e-55 1.887313418911687e-55 8454/8773/5689/127544/11065/221687/9666/84937/55070/5682/55819/93611/8916/3107/7321/51665/65264/122769/9021/10484/8697/26235/9817/9039/154881/7174/6478/811/143471/5705/57674/10333/9690/8452/5709/9978/5695/23304/567/55236/54620/4734/7337/84676/7704/3106/3093/10489/5711/23327/51465/10616/5683/929/3309/89910/25898/5699/7328/9632/7428/5702/22954/401036/83737/51529/140461/10075/29945/79176/8924/90135/56658/51434/6468/10425/25793/23295/3133/51666/90293/54461/29882/7334/92591/55182/84961/4591/3551/7332/5696/5691/9820/55658/7314/996/10324/283807/9354/5718/197131/8945/51088/64410/10952/146330/51320/5700/122706/5707/10477/148581/92912/23198/10533/140462/6892/51130/8517/6810/6477/7323/10517/9604/22872/64718/4008/7096/84861/11059/84085/27252/51444/26118/51433/9861/26249/55905/10134/143279/6502/5698/27246/5692/5713/9903/201456/26190/79654/5710/9040/7324/5719/64682/8925/51191/6233/3685/26091/6047/131405/868/136371/6396/127247/1535/5930/11275/29116/26268/115290/51725/140459/23608/55585/64320/51132/899/3135/23352/26224/4688/10293/114088/285231/653361/142678/246184/142686/387522/151636/11146/255488/9616/91694/10802/10193/6890/140739/821/150726/390594/81559/2209/144699/5706/200845/79876/26263/9554/8881/7326/6049/57630/89890/22888/29927/7317/80196/140456/55958/84078/5714/26272/8651/64219/140458/5688/55336/26270/5687/63893/89122/118424/5708/55008/2923/10422/84727/695/90933/63891/9246/10393/9902/5704/9870/9520/4012/25847/7327/51343/7311/9871/7318/55175/9320/26232/57520/5694/8673/92369/3105/997/84261/7325/140691/23643/57154/1147/140460/5684/79754/6737/8065/5720/57531/84708/7319/54850/79791/26046/991/84231/10273/7320/5690/223082/5717/25897/9491/6500/26259/10197/7099/53339/154214/7336/4615/64750/51619/23376/6891/54778/142689/7316/10213/114907/54926/7335/222235/25831/7322/5715/9867/5701/9341/23291/5685/5686/55521/114609/55294/135892/8453/80176/8139/126433/4689/26267/948/142685/5716/90025/7064/84541/23194/55284/3134/80204/26234/27338/7097/23014/1536/90678/5693/5721/51676/10427/57542/642/4360 353 Human_herpesvirus_1 R-HSA-5683057 MAPK family signaling cascades 287/6371 294/10654 4.269887157931999e-55 2.0096935556666608e-52 7.730743064887409e-53 2308/5689/374/2118/3725/2674/4893/6711/2250/1437/71/5682/1844/1850/1848/5526/817/84292/7039/27327/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/22866/5605/4609/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/192669/4296/5894/1847/3563/1741/9542/1739/2885/6709/8660/8997/8826/5518/2252/1740/4140/4343/2253/3845/5623/3265/4763/3569/5062/5696/5691/2323/7314/3572/5879/5515/5923/5718/818/10156/1839/3667/8823/8831/2065/5700/3815/122706/5707/5567/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/3337/4902/2260/5528/2902/10125/983/3718/2249/25780/6714/9861/2248/5519/64096/3567/2247/5698/5692/10435/5713/2335/80824/1445/5710/8555/896/5719/2906/6233/51332/2266/2246/7514/2251/5154/115727/2243/1843/3570/255324/26523/369/801/200734/7297/5781/4747/10602/1846/11221/28956/805/22821/9462/3562/6464/6712/2904/5747/283455/3674/7010/5568/2322/2675/3315/409/5706/1438/673/2676/8315/221002/2263/4233/5597/84078/5714/64926/5566/6710/5688/5159/5687/5708/3084/5063/5529/816/998/9693/9365/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/5058/5924/7529/5595/25759/5516/8822/5786/27161/815/5684/685/5720/2309/5604/3561/5525/153090/10642/10048/5690/57690/5717/9491/3568/8817/10817/10197/192670/5596/8550/54518/2254/7316/10213/152831/1950/3560/57731/26281/10818/5715/8437/10256/2261/5701/27040/5922/5685/2255/8649/53358/5686/2066/6708/27006/8556/5979/23112/1742/5527/5716/88/5906/5155/9048/4254/5896/399473/808/3559/8202/5693/5721/5245/5156/161742/284 287 Human_herpesvirus_1 R-HSA-5684996 MAPK1/MAPK3 signaling 251/6371 255/10654 5.967188455759701e-51 2.1064175248831745e-48 8.102813797821068e-49 5689/374/2674/4893/6711/2250/1437/71/5682/1844/1850/1848/5526/817/84292/7039/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/22866/5605/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/1847/3563/1741/9542/1739/2885/6709/8660/8826/5518/2252/1740/4140/2253/3845/5623/3265/4763/3569/5696/5691/2323/7314/3572/5515/5923/5718/818/10156/1839/3667/8823/8831/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/4902/2260/5528/2902/10125/983/3718/2249/25780/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/80824/1445/5710/5719/2906/6233/51332/2266/2246/2251/5154/115727/2243/1843/3570/255324/369/801/200734/7297/5781/4747/1846/11221/28956/805/22821/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/409/5706/1438/673/2676/8315/221002/2263/4233/84078/5714/64926/6710/5688/5159/5687/5708/3084/5529/816/9693/9365/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/5924/7529/5595/25759/5516/8822/5786/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10817/10197/54518/2254/7316/10213/152831/1950/3560/57731/26281/10818/5715/8437/10256/2261/5701/27040/5922/5685/2255/8649/53358/5686/2066/6708/27006/5979/1742/5527/5716/88/5906/5155/9048/4254/399473/808/3559/5693/5721/5245/5156/161742/284 251 Human_herpesvirus_1 R-HSA-9607240 FLT3 Signaling 261/6371 267/10654 1.4043025598327574e-50 3.9657504289677066e-48 1.5255160439446377e-48 5295/5689/374/2674/4893/6711/2250/1437/71/5682/1844/5291/1850/1848/5526/817/84292/7039/5908/3082/143471/2064/5705/8452/6776/4684/5709/9978/5695/1852/2668/22866/5605/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/1847/3563/1741/9542/1739/2885/6709/8660/8826/9846/5518/2252/1740/4140/2253/3845/5623/3265/4763/5696/5691/2323/7314/5515/54106/5923/5718/818/10156/1839/5290/3667/8823/8831/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/57761/5921/4902/2260/5528/2902/10125/3718/2249/25780/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/80824/1445/5710/5719/2906/6233/51332/2266/2246/2251/5154/115727/2243/1843/6777/255324/369/801/200734/5781/30849/4747/1846/11221/28956/805/22821/5170/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/409/5706/1438/673/2676/8315/221002/2263/4233/84078/5714/64926/6710/5688/5159/5687/5708/3084/5529/816/9693/208/9365/6654/5704/10718/3716/7311/7450/1956/60/5536/2549/5694/5924/7529/5595/25759/5516/8822/5786/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10817/10197/54518/2254/7316/10213/152831/1950/3560/5289/3055/57731/26281/10818/5715/8437/10256/2261/5701/27040/5922/5685/2255/8649/53358/5686/2066/6708/27006/5979/1742/5527/5716/88/5906/5155/9048/4254/5296/399473/808/3559/5693/5721/5245/5156/161742/284 261 Human_herpesvirus_1 R-HSA-5673001 RAF/MAP kinase cascade 245/6371 249/10654 1.3038843879625572e-49 3.068474593005218e-47 1.1803584985766309e-47 5689/374/2674/4893/6711/2250/1437/71/5682/1844/1850/1848/5526/817/84292/7039/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/22866/5605/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/1847/3563/1741/9542/1739/2885/6709/8660/8826/5518/2252/1740/4140/2253/3845/5623/3265/4763/5696/5691/2323/7314/5515/5923/5718/818/10156/1839/3667/8823/8831/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/4902/2260/5528/2902/10125/3718/2249/25780/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/80824/1445/5710/5719/2906/6233/51332/2266/2246/2251/5154/115727/2243/1843/255324/369/801/200734/4747/1846/11221/28956/805/22821/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/409/5706/1438/673/2676/8315/221002/2263/4233/84078/5714/64926/6710/5688/5159/5687/5708/3084/5529/816/9693/9365/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/5924/7529/5595/25759/5516/8822/5786/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10817/10197/54518/2254/7316/10213/152831/1950/3560/57731/26281/10818/5715/8437/10256/2261/5701/27040/5922/5685/2255/8649/53358/5686/2066/6708/27006/5979/1742/5527/5716/88/5906/5155/9048/4254/399473/808/3559/5693/5721/5245/5156/161742/284 245 Human_herpesvirus_1 R-HSA-3700989 Transcriptional Regulation by TP53 337/6371 365/10654 1.9456284747181492e-46 3.9246105804314666e-44 1.5096906660970904e-44 6884/6875/834/5563/3725/9134/4436/83990/64769/9156/57060/1763/7531/1459/79370/7486/6874/10971/9997/133383/9212/5982/27327/7295/7533/2810/55367/1460/11200/472/53632/79813/5431/7001/639/5435/5433/1869/28996/84289/1457/6790/25904/29117/4194/1647/5928/1432/1387/4683/10325/56950/51499/2965/84126/8738/5439/192669/1107/8900/6873/5371/2475/672/55571/6881/2967/51616/5518/1386/55835/10670/4513/4343/6117/11198/7159/57472/904/144455/85456/29883/51497/51230/637/64121/83695/7296/7314/5515/1263/27166/23368/9377/23774/6118/2176/3622/7027/6446/2936/7832/51422/7249/404672/898/117584/27244/7534/332/5438/5934/64065/1351/116028/890/10769/983/1643/8797/9656/5519/27154/5458/83860/57459/2821/2177/10000/5985/2877/900/7994/2068/54541/3066/7157/5984/6233/1121/1025/2353/604/63970/839/10419/5325/50484/5600/9167/6883/7936/6829/79733/26523/7874/317/2744/5608/5884/5810/57521/26155/26013/5875/253260/28956/25920/5170/80010/2963/5434/83667/1820/7862/1029/389541/5457/9219/8445/7532/5436/1345/55240/204851/6878/4869/5931/58528/4850/4292/580/11073/891/84987/80196/54971/4331/5366/641/5111/1108/8148/2966/246175/64223/2962/84883/6119/147923/3364/5571/10524/54457/4848/8812/144715/23019/1616/843/6794/54815/94241/1874/10128/25824/6009/905/1111/2071/55215/8626/208/79109/55004/7311/7161/5562/6880/6908/5983/1340/4697/5564/6882/5565/1020/53615/10397/8795/5432/665/7248/6877/7529/5516/1017/27161/27113/9891/6917/5440/27165/5305/8621/902/5883/25946/9540/5430/10111/8793/207/22974/57690/835/4849/1027/58484/3486/355/6749/545/5441/8794/192670/153129/8550/7469/9337/7316/6872/2539/1026/54205/55615/5933/124446/5395/6879/9150/112858/5876/143686/10848/5437/1350/9099/8649/28984/51755/2033/995/5728/3065/91875/6827/23112/10498/10542/5527/1349/2968/5932/8851/5300/7156/581/1327/3276/5052/138474/133746/1022/8178/10919/4193 337 Human_herpesvirus_1 R-HSA-5663202 Diseases of signal transduction 345/6371 377/10654 3.500255214748895e-45 6.177950454031799e-43 2.3764890668558286e-43 5295/8454/2308/27123/5689/374/4893/11052/2250/5335/71/79718/5682/5291/892/5526/817/1452/7039/9530/613/182/5908/3082/941/55109/143471/23385/2064/5705/54845/5431/6776/5435/5709/9978/5433/5695/8546/9759/9612/22866/5605/4609/145226/4089/22938/5037/5711/1387/3717/10827/4088/2244/6907/5683/145957/324/2534/3690/408/9965/5699/6400/8312/11064/5439/2264/5702/4296/5894/6868/9794/9542/2885/2475/8660/79412/51009/8826/9846/5518/57534/2252/6469/1185/4140/7040/2253/3845/388585/3265/4763/5696/7750/5691/7314/5879/5515/5718/818/5947/8805/1839/26127/5290/3667/8823/79885/2065/2648/9734/55869/55750/5700/3815/122706/5707/10956/8844/51564/7094/8322/55534/5594/3280/2069/84335/8074/7249/23198/84441/7414/10533/10013/23164/2260/5438/5528/83933/3714/89780/102/57085/2249/6714/2099/9861/2248/5519/9061/8850/399687/2932/7046/2247/5698/5880/10000/5692/5713/2335/1445/5710/3066/2280/5719/6233/2266/7409/2246/4040/27248/2251/5154/3932/2931/2243/7855/118788/6777/255324/369/801/5781/5663/940/1523/57670/253260/805/5170/2963/5434/7276/6464/142678/572/283455/3674/5436/4303/409/930/5706/6199/10046/9208/84447/673/8315/6774/2263/4233/8658/1024/5714/6772/6934/64223/10014/2962/8503/5688/5159/5687/29851/5708/3084/26508/9148/5529/816/4087/208/9365/6654/5704/10718/79109/56829/7048/23493/7311/5293/7450/1956/11160/60/9444/2549/611/5694/4851/5432/22916/11140/7529/5595/5516/4000/1147/8822/27044/815/5440/5684/22906/8841/685/5720/8087/1487/2309/5604/1499/10018/5525/10142/842/139285/5430/23462/207/5690/5717/27121/1027/9491/6500/8817/5441/10197/54518/2100/2254/4686/7316/10213/152831/1950/9611/1026/55615/26281/10818/7415/5715/80853/10256/2261/5701/867/5437/5685/2255/3164/3320/5686/2033/54894/391/55294/5728/3065/2066/27006/942/5527/1488/5716/1385/5906/5155/54567/4254/5296/808/3516/9715/5693/5721/5245/5156/4193 345 Human_herpesvirus_1 R-HSA-5663205 Infectious disease 349/6371 383/10654 1.3233555293019482e-44 2.076197785971501e-42 7.986566703155618e-43 3839/6158/6884/23165/6875/5689/6138/2237/6227/7852/6206/6234/6191/162/6128/5682/6132/6129/27243/6874/6176/1174/811/6224/6146/348995/6154/143471/6202/57122/5705/3981/6169/5431/23511/5435/5709/6175/9978/5433/6218/5695/2960/292/567/51271/6173/23279/5605/6167/5711/23327/116832/29082/8732/23225/5683/2965/2534/6156/27183/5699/6143/5439/5702/6456/6873/3836/6139/30011/2885/163/9972/6881/2967/51616/3921/8021/7040/11198/904/55690/51497/5062/55746/6208/5696/6170/5691/92421/7296/7314/5879/5718/137492/3303/8945/6203/51606/1839/161/402569/5606/6147/25978/5700/51160/122706/5707/2959/8027/10053/6222/2060/7518/8106/23198/404672/9636/10015/91782/5438/6134/3978/10762/79720/6155/1500/4836/926/9397/6714/6231/9861/79902/6142/11168/9883/23521/89853/83860/999/5698/9146/6455/5692/5713/5710/2068/5902/6207/5478/5719/6233/6844/7514/1025/3932/1213/5610/1211/6188/6396/129401/6883/7936/1175/6829/801/5608/8907/200916/6122/2957/940/805/25920/6230/60489/928/1173/4928/2963/3838/5434/5903/6857/6194/55706/7175/79643/6166/1938/5436/6136/6878/3841/6125/4869/821/5706/6232/160/6160/6616/293/5611/920/4233/4331/5714/6193/4927/6210/6229/8148/6205/2966/2962/10898/3840/5688/54457/8812/5687/5708/128866/140801/6235/905/6181/2071/5901/8086/5704/3326/7311/6223/25873/93343/6880/6908/7251/8905/5694/3304/1104/2547/9045/6882/2961/6187/6416/5432/6168/22916/1234/6157/6137/6877/5905/6144/3837/6917/81929/5440/164/5684/9349/8065/4736/5720/902/51121/9631/5604/1499/3159/6159/6217/3843/5430/6152/5690/7520/5717/9491/6500/127833/6749/51065/6141/79023/6123/5441/23636/10197/7469/919/130340/6164/4686/7316/10213/6872/53371/3055/6209/9688/11224/6165/8731/6130/6879/9150/5715/9525/6204/5701/2958/867/6228/5437/5685/3320/8815/5686/6124/6827/5609/2968/6843/5716/6189/808/6135/6201/375/6161/138474/1022/5693/10254/5721/6457/8178/8480/6133/291 349 Human_herpesvirus_1 R-HSA-9006925 Intracellular signaling by second messengers 286/6371 305/10654 3.946024646604072e-43 5.571786801004949e-41 2.1433144396291594e-41 5295/1912/2308/5689/374/3725/6591/3643/2250/5335/5682/5291/1822/1459/5526/9112/817/6045/5578/7039/5582/27327/80012/3082/1460/941/143471/2064/5705/5709/5695/107/1457/1911/4734/11060/5711/5928/10325/5683/145957/2534/23512/9965/57332/5699/2444/2264/3630/5702/192669/1107/8975/3654/5371/9542/2885/2475/51135/8660/5518/1386/10670/2252/4343/2253/64121/5696/814/5691/7314/5879/5515/5718/818/1839/5290/3667/8823/90865/2065/23186/5700/3815/122706/5707/5567/2146/51564/5594/2069/84335/84232/8074/7249/23198/112/57761/2260/5573/5528/111/2249/6714/2099/9861/7101/81847/2248/5519/2932/84733/57459/2247/5698/5880/10000/5692/5713/5710/3066/7157/5613/5719/6233/5580/7409/2246/2251/5154/3932/2931/118788/331/8726/5153/196883/8394/115/255324/26523/7874/801/5781/57521/23608/940/6015/253260/28956/805/5170/3838/572/23239/389541/9219/8535/4303/5568/930/5931/58528/5706/6199/113/2263/4233/8658/5714/10645/1108/2122/64223/5566/84254/10014/8503/5688/5159/5687/29851/5708/3084/54815/6009/5529/816/7189/208/9365/5577/5704/10718/79109/55004/57504/7311/5293/1956/648/2549/5694/23466/53615/109/5595/3556/5516/1147/8822/27161/815/5684/8841/685/5305/5720/2309/5468/5525/5575/842/5978/8870/10273/207/5690/57690/5717/1027/9491/8817/114/3708/10197/108/192670/4615/153129/2100/2254/7316/10213/152831/1950/1026/55615/10768/26281/57167/10818/5715/1958/2261/5701/5576/5685/2255/8649/3164/5686/391/5728/6615/3065/2066/27006/23028/942/5987/23112/10542/5527/5716/1385/5155/4254/5296/5581/808/5693/5721/5137/5156/4193 286 Human_herpesvirus_1 R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 236/6371 244/10654 7.933698500316236e-43 1.0183983893133205e-40 3.9175008862805534e-41 8449/23165/6633/8683/6431/84271/55696/4904/51639/51585/9128/199746/23450/348995/57122/5431/9092/23511/81608/5435/6625/5433/51645/3190/1477/9416/65109/56339/22826/23279/8233/22938/988/23020/23225/6631/3181/5439/1660/9410/6638/57721/9877/9972/8021/3312/10907/10291/55746/26121/10262/7919/53981/6432/10084/8563/6430/51340/56001/6627/6936/83443/11051/80145/9129/9879/10081/8106/51690/27238/55749/5438/85313/10762/54883/22794/9785/11338/1655/9343/29107/3185/4116/6626/11157/285755/1478/24144/79902/9883/51213/10236/10250/4670/26097/51362/10465/55660/25949/23283/2521/1977/3191/10285/6636/23524/10914/57187/6396/129401/79228/8175/2733/84950/3188/84324/56259/5725/1994/10450/7536/4928/2963/6635/5434/5903/220988/6632/10283/55706/7175/24148/154007/7884/23350/5436/10523/6428/27258/10212/6637/55110/5093/55954/84321/6429/57819/4927/10181/2962/10898/10569/23658/6434/9295/84844/10482/51692/10421/11193/8086/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/81929/5440/55599/51691/10946/9631/27339/5430/79869/85437/11325/57703/3184/25804/29894/9589/11017/51503/3178/79023/5441/23636/3183/79622/10594/4686/8189/23398/10713/53371/10978/5546/7307/10772/9688/9984/5437/6629/10189/10949/51729/11066/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/84248/6427/5356/57461/84991/8480/10992/55339/6628 236 Human_herpesvirus_1 R-HSA-8951664 Neddylation 227/6371 234/10654 5.6138393935078926e-42 6.605617686360954e-40 2.5410009886404147e-40 8454/5689/56995/5682/64344/80344/80067/93611/55884/7321/51665/122769/9021/4738/26235/9817/9039/154881/5929/3091/143471/5705/140825/8452/5709/9978/5695/54620/7704/10980/10489/5711/7347/5683/23113/5699/79269/10987/7428/5702/401036/140461/79176/90135/6468/26094/25793/1154/51666/90293/54461/92591/84961/5696/5691/9820/7314/51514/10324/283807/5718/51397/54165/8945/51088/64410/23363/23038/146330/5700/122706/5707/23198/140462/55827/51130/28991/332/7323/9306/10517/50717/4008/84861/84085/79016/27252/1643/26118/9861/122416/26249/6502/90864/55832/5698/5692/10920/5713/9903/201456/26190/10238/5710/9040/5719/10116/6233/83987/136371/8835/127247/11275/54939/26268/115290/54951/51725/140459/55208/10537/8451/899/26224/23412/9655/149951/285231/142686/9616/140739/5931/150726/390594/144699/5706/200845/26263/8450/89890/140456/55958/84078/5714/55527/26272/140458/5688/55336/26270/5687/1161/5708/1642/84727/5704/2873/7311/2034/55175/8533/26232/51667/5694/51122/92369/84261/150684/51138/56929/9318/140460/5684/79754/8065/5720/29099/11091/25879/54850/79791/5690/5717/9491/6500/28952/26259/10197/53339/142689/7316/10213/114907/64708/222235/54876/7322/5715/5701/23291/170622/5685/5686/55294/8453/123879/80176/8139/23142/126433/26043/26267/142685/5716/84541/23194/80204/26234/8883/23014/8816/5693/5721/84259/51676/50813/57542 227 Human_herpesvirus_1 R-HSA-449147 Signaling by Interleukins 401/6371 461/10654 3.8806716070678683e-39 4.2150063916767925e-37 1.6213980155846319e-37 5295/729230/8454/3605/7124/2308/834/1052/5689/3725/7291/5777/9252/1437/4790/5682/5291/1511/26469/5657/5783/27178/1848/356/3593/246/9021/8878/6624/5908/3082/5743/3091/941/143471/10538/3383/5705/11009/6097/6349/6657/3576/3313/3662/6776/3688/4985/5709/6175/9978/2920/5695/84868/1435/4792/3936/59307/7133/3606/177/4609/3603/5898/5711/4988/1432/3558/3717/4088/836/5683/200081/2534/2162/5699/3181/5702/4001/3654/3563/2885/85480/51135/8660/282618/6196/3594/1154/50604/9846/6347/5518/1386/6382/9235/7040/3588/6197/4282/7334/3600/3312/1399/3551/55801/3569/5062/5696/5691/51231/4692/7314/3572/3596/5515/257397/3598/5718/54014/10148/8945/1326/5601/1072/3635/3592/5290/3667/6627/5606/90865/64109/9049/11213/3587/7412/5700/122706/5707/27250/8767/1849/29110/1439/5594/4582/23198/23118/6367/4312/9987/8517/6778/7534/6810/332/5528/4313/3565/3934/3976/50615/3185/5970/5443/9261/3718/3627/8809/9861/149233/5519/5598/4208/3567/598/2247/5698/5692/5713/2335/595/6195/5710/3458/10454/7157/5478/5719/6233/7525/6844/7409/2353/604/6809/3932/7076/302/552900/51561/3570/8835/5600/6777/6773/7850/7297/5781/5608/4791/1846/59067/3557/9655/3562/351/6464/3566/6597/5782/387522/6351/7184/9180/3589/6775/50616/3684/9446/3595/54472/821/4318/5706/3726/58480/301/4478/1438/53833/3581/6616/79155/6774/920/6850/5780/1440/5714/6772/8651/7867/5566/64127/8503/1901/3552/2889/5688/79923/5687/4067/29760/3636/5708/5602/29949/3656/57162/5771/998/6648/116379/7189/163702/112744/6654/5704/7006/3716/7311/2939/1270/6888/5293/2185/6655/6356/5008/5694/246778/6416/1234/3586/3554/829/5595/3556/5516/6095/1147/5778/1845/596/5684/2208/5720/6885/2309/5604/4215/3561/3578/10392/207/5292/5451/7422/5690/3553/2625/1230/5717/2919/9491/6500/3568/25930/246330/10197/4615/3597/2357/1436/7316/10213/3560/6352/4314/7335/1441/4205/3055/1026/6348/4793/3146/6647/6364/5715/7132/5701/867/466/6950/23291/5685/3320/5686/4843/9466/6288/2002/942/6285/5609/1398/58985/948/5716/1385/53832/6363/3575/4507/6845/5896/5296/6935/3687/5599/5784/7431/375/3977/3559/3574/3929/3162/1489/57161/1278/4170/5693/3689/5721/3601/5724/5034 401 Human_herpesvirus_1 R-HSA-1257604 PIP3 activates AKT signaling 249/6371 264/10654 6.525278416047123e-39 6.581209373898956e-37 2.531611776451365e-37 5295/1912/2308/5689/374/3725/6591/3643/2250/5682/5291/1822/1459/5526/9112/6045/7039/27327/80012/3082/1460/941/143471/2064/5705/5709/5695/1457/1911/4734/11060/5711/5928/10325/5683/145957/2534/23512/9965/57332/5699/2444/2264/3630/5702/192669/1107/8975/3654/5371/9542/2885/2475/51135/8660/5518/1386/10670/2252/4343/2253/64121/5696/5691/7314/5879/5515/5718/1839/5290/3667/8823/90865/2065/23186/5700/3815/122706/5707/2146/51564/5594/2069/84335/84232/8074/7249/23198/57761/2260/5528/2249/6714/2099/9861/7101/81847/2248/5519/2932/84733/57459/2247/5698/5880/10000/5692/5713/5710/3066/7157/5719/6233/7409/2246/2251/5154/3932/2931/118788/331/8726/8394/255324/26523/7874/5781/57521/23608/940/6015/253260/28956/5170/572/23239/389541/9219/8535/4303/930/5931/58528/5706/6199/2263/4233/8658/5714/1108/2122/64223/10014/8503/5688/5159/5687/29851/5708/3084/54815/6009/5529/7189/208/9365/5704/10718/79109/55004/57504/7311/5293/1956/648/2549/5694/23466/53615/5595/3556/5516/1147/8822/27161/5684/8841/685/5305/5720/2309/5468/5525/842/5978/8870/10273/207/5690/57690/5717/1027/9491/8817/10197/192670/4615/153129/2100/2254/7316/10213/152831/1950/1026/55615/26281/57167/10818/5715/1958/2261/5701/5685/2255/8649/3164/5686/391/5728/6615/3065/2066/27006/23028/942/5987/23112/10542/5527/5716/1385/5155/4254/5296/5693/5721/5156/4193 249 Human_herpesvirus_1 R-HSA-72172 mRNA Splicing 186/6371 191/10654 2.3184115784825842e-35 2.182398099211606e-33 8.395090347347464e-34 8449/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/5431/9092/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/8233/22938/988/23020/6631/3181/5439/1660/9410/6638/3312/10907/10291/26121/10262/53981/6432/10084/6430/51340/6627/6936/83443/11051/9129/9879/10081/8106/51690/27238/55749/5438/85313/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/10236/10250/4670/51362/10465/55660/25949/23283/2521/3191/10285/6636/23524/10914/8175/84950/3188/56259/5725/1994/10450/7536/2963/6635/5434/220988/6632/10283/24148/154007/23350/5436/10523/6428/27258/6637/55110/5093/55954/6429/57819/10181/2962/10898/10569/23658/6434/9295/84844/51692/10421/11193/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/55599/51691/10946/27339/5430/79869/85437/11325/57703/3184/25804/29894/11017/51503/3178/5441/3183/79622/10594/4686/8189/23398/10713/10978/5546/7307/10772/5437/6629/10189/10949/51729/11066/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/57461/84991/10992/55339/6628 186 Human_herpesvirus_1 R-HSA-72163 mRNA Splicing - Major Pathway 178/6371 183/10654 1.251869444812905e-33 1.1047747850473886e-31 4.24976732581223e-32 8449/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/5431/9092/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/22938/988/23020/6631/3181/5439/1660/9410/6638/3312/10907/10291/26121/10262/53981/6432/10084/6430/51340/6627/6936/83443/11051/9129/9879/8106/51690/27238/55749/5438/85313/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/10236/10250/4670/51362/10465/55660/25949/23283/2521/3191/10285/6636/23524/10914/8175/84950/3188/56259/5725/1994/10450/7536/2963/6635/5434/220988/6632/10283/24148/23350/5436/10523/6428/27258/6637/55110/5093/6429/57819/10181/2962/10898/10569/23658/6434/9295/84844/51692/10421/11193/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/51691/10946/27339/5430/79869/11325/57703/3184/25804/29894/11017/51503/3178/5441/3183/10594/4686/8189/23398/10713/10978/5546/7307/10772/5437/6629/10189/10949/51729/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/57461/84991/10992/55339/6628 178 Human_herpesvirus_1 R-HSA-913531 Interferon Signaling 191/6371 199/10654 3.080597611560557e-33 2.558708133837357e-31 9.842652430744567e-32 80263/3839/3443/23165/201626/5777/5335/960/5770/3107/817/9021/348995/317649/3383/57122/11274/55223/3662/3115/23511/4684/567/4734/6672/3113/23279/3106/8672/3459/3717/23225/3117/1973/11074/3836/5371/4599/684/9972/3133/3429/117854/8021/3127/91543/7334/4938/4261/55746/5696/7314/3445/818/402569/115362/7412/10410/85363/9830/163351/9636/2634/3444/10762/2317/115361/103/3434/10475/3433/79902/23586/9883/3451/10437/3448/1981/10612/3458/3661/7324/1977/3439/51191/6233/5580/81603/10107/5610/10581/3452/4940/6396/3437/129401/6773/7297/5781/3430/3660/3446/8554/3135/3665/3120/4928/3838/5903/10379/55706/7175/3455/2316/2633/4600/3841/3123/23650/2209/8638/25820/1982/7706/23087/9470/3122/3394/3663/6772/8651/4927/3659/3840/25939/2635/3440/5771/3454/816/8086/10346/9246/3716/7311/7318/7726/79097/3456/53840/3105/1974/5595/3460/815/3837/81929/3441/6737/51447/9631/23321/4281/3119/4502/54739/79023/2537/23636/3449/51127/7316/53371/8519/3664/9688/6041/1958/4939/388646/7341/6059/55128/3669/3134/5300/9775/80128/5495/5724/8480 191 Human_herpesvirus_1 R-HSA-453274 Mitotic G2-G2/M phases 190/6371 198/10654 5.0034517285664533e-033 3.9249299115199065e-31 1.5098135040586492e-31 114791/10844/8454/5689/440145/5682/7531/11190/203068/54801/51807/63943/347688/51400/79441/143471/10381/5705/5116/5048/5709/9978/1869/5695/8655/6790/9702/5711/5928/7846/7840/5683/5699/11064/5702/5520/81027/8900/28227/5518/55835/29922/23332/7465/93323/5696/5691/7314/5515/5718/8945/4659/5700/122706/5707/1454/23198/993/890/983/9861/79959/5519/5698/5692/5713/80097/10376/5710/10540/7157/85378/5719/6233/7514/54930/54820/1453/27229/9793/4218/5500/84617/2305/11258/22981/8636/51512/7532/84962/55125/10382/121441/7277/5706/9133/286826/9814/653784/23354/728642/891/9738/4331/1639/5714/55722/4957/5566/5688/5687/91750/7283/5708/347733/22919/984/10426/22994/79866/1069/5577/5704/3326/55957/7311/10133/10383/5347/84790/80184/5694/22897/5108/7280/10806/1778/5516/115106/1017/22822/22995/55559/5684/994/5720/4605/902/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/112714/1781/7316/10213/80321/1026/10121/1871/5715/84131/9088/5701/23291/5685/3320/5686/2033/995/10733/4751/27175/80254/5716/23194/9662/55142/1022/8481/5693/5721/132660/55755 190 Human_herpesvirus_1 R-HSA-69275 G2/M Transition 188/6371 196/10654 1.3188069615414142e-32 9.800818051034088e-31 3.770107435763822e-31 114791/10844/8454/5689/440145/5682/7531/11190/203068/54801/51807/63943/347688/51400/79441/143471/10381/5705/5116/5048/5709/9978/5695/8655/6790/9702/5711/5928/7846/7840/5683/5699/11064/5702/5520/81027/8900/28227/5518/55835/29922/23332/7465/93323/5696/5691/7314/5515/5718/8945/4659/5700/122706/5707/1454/23198/993/890/983/9861/79959/5519/5698/5692/5713/80097/10376/5710/10540/7157/85378/5719/6233/7514/54930/54820/1453/27229/9793/4218/5500/84617/2305/11258/22981/8636/51512/7532/84962/55125/10382/121441/7277/5706/9133/286826/9814/653784/23354/728642/891/9738/4331/1639/5714/55722/4957/5566/5688/5687/91750/7283/5708/347733/22919/984/10426/22994/79866/1069/5577/5704/3326/55957/7311/10133/10383/5347/84790/80184/5694/22897/5108/7280/10806/1778/5516/115106/1017/22822/22995/55559/5684/994/5720/4605/902/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/112714/1781/7316/10213/80321/1026/10121/5715/84131/9088/5701/23291/5685/3320/5686/2033/995/10733/4751/27175/80254/5716/23194/9662/55142/1022/8481/5693/5721/132660/55755 188 Human_herpesvirus_1 R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 398/6371 473/10654 8.664725338565597e-32 6.117296089027311e-30 2.3531569866841306e-30 5295/3675/374/5777/627/3643/9252/4893/857/2250/2670/5335/71/5579/5770/5291/26469/1848/10653/5578/7039/3249/1785/5908/3082/51741/23385/2064/535/1280/54845/5431/50617/6696/6776/5435/3688/10312/5433/5753/7423/4734/10413/5605/3910/8569/5898/1432/3717/55824/145957/2534/9475/3690/9965/5439/2264/5603/3630/6456/83737/6868/7072/4145/9542/30011/2885/2475/8660/6093/163/7073/6196/9846/1759/5518/8440/2252/8874/9564/2253/6197/3845/2561/3265/1399/8877/5062/4486/2560/10603/10252/51231/56034/2323/5829/7314/5879/5515/6387/5607/54106/51606/1839/3918/161/5290/55879/3667/5899/8823/23768/6678/2065/5340/526/3815/5567/8027/10006/537/9550/1849/2060/9114/5594/2069/8074/284217/9101/23118/57761/5921/6778/2260/5438/348/5528/9306/1500/3185/1298/11059/102/9261/2249/6714/2099/2248/1447/5519/5598/4208/4670/2567/2566/4909/2321/2247/4914/529/10810/10000/9146/6455/2335/64759/6195/3909/3728/8471/1445/84951/3925/6233/7525/7410/5580/2324/7409/2246/23191/3685/2251/5154/57610/3932/1213/3791/1729/1211/29924/1535/5600/6777/255324/1175/523/6300/528/801/200734/5781/30849/5663/2554/5725/1846/253260/805/25920/5170/4908/1173/116/4688/2963/5434/5590/6464/80310/85440/653361/5241/2904/6461/5747/5782/7424/5436/10019/10193/5568/2322/7074/3315/2241/10451/4318/382/1277/160/3912/673/527/6774/2263/4233/10152/6772/8651/26052/7867/64223/5566/2962/1003/8503/5795/2889/10163/5159/4067/3084/23767/55845/5063/5771/1111/5796/998/3481/2886/3913/80004/208/9365/6654/5867/10718/79109/7006/5900/7311/2185/387/53834/1956/60/2549/5058/1020/5432/3480/22916/11140/53916/4916/7529/63916/5595/25759/5516/8822/1845/10253/9402/5440/8065/685/26018/558/4915/1495/5604/1499/4690/1299/5430/10048/10273/207/7422/10458/2562/3178/8817/9982/10817/3708/5441/58513/2254/4686/7316/152831/1950/9611/51072/9047/4205/5289/57498/55615/3915/10768/26281/10818/1281/3673/23545/2261/867/5437/466/245972/2255/53358/3320/4846/4803/2002/2066/3914/27006/6285/1742/200958/1398/3187/4689/5774/1385/5228/5906/3479/5155/23163/4254/8851/5296/5581/581/808/10076/7059/1536/7057/1278/11033/10254/6457/51382/5156/161742/9296/2887/2242 398 Human_herpesvirus_1 R-HSA-453279 Mitotic G1-G1/S phases 147/6371 149/10654 1.4055739282834536e-30 9.45081136541065e-29 3.635469408492542e-29 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/1031/4998/5711/5928/10926/3717/5683/990/5699/5702/5520/8900/55388/1032/28227/1030/5518/6117/5001/7465/5558/5696/5691/7314/5515/6241/5718/6118/25/23594/7027/5700/5707/7153/898/91768/5934/5557/993/890/1876/983/6714/9861/5519/6502/5698/10000/5692/5713/595/4175/5710/896/5719/6233/7298/23649/1719/1163/1859/4999/4172/26271/1019/5000/8318/1029/54107/4173/5706/286826/891/4331/5714/5111/51053/6119/5688/5687/91750/5427/4067/5708/1874/81620/208/1870/5704/29935/55957/23595/7311/5694/4176/5516/56655/1017/894/5684/5720/4605/902/8317/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5933/5426/4171/1871/5715/5701/5685/5686/1021/3065/5716/1022/5693/5721/7083/132660/1028 147 Human_herpesvirus_1 R-HSA-69242 S Phase 157/6371 161/10654 3.09258049305824e-30 1.9848743891810162e-28 7.635270499607904e-29 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/10274/5925/143471/5705/5709/5422/9978/1869/4174/5753/5695/84515/4609/4998/5711/5928/5683/990/5699/5702/8900/51529/29945/51434/157570/6117/29882/5001/10714/7465/5558/5696/5691/7314/996/5718/6118/23594/7027/5700/122706/5707/64785/23198/898/3978/91768/5934/5557/993/890/51433/9861/2932/6502/5698/10000/5692/5985/5713/119504/595/4175/5710/5984/7324/5719/64682/6233/113130/23649/1163/5424/4999/4172/1019/5000/8318/246184/54107/4173/5706/286826/23047/8881/5885/4331/5425/5714/5111/6119/5688/5687/91750/5427/5708/1874/8243/81620/10393/208/5704/55957/51343/23595/7311/25906/51659/5983/5694/4176/56655/1017/5684/994/5720/902/57804/207/9837/5690/5717/1027/9491/6500/23244/10735/10197/4149/7316/10213/1875/1026/5426/4171/5715/5701/5685/5686/9126/5716/114799/5981/1022/5693/5721/132660 157 Human_herpesvirus_1 R-HSA-2555396 Mitotic Metaphase and Anaphase 190/6371 202/10654 1.9630198005822678e-29 1.2051234601835487e-27 4.635781313960871e-28 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/5520/81027/51529/4001/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/221496/7444/5698/5692/5713/91687/119504/11243/10376/5710/7324/83540/2010/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/26271/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/5708/347733/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/7443/112714/1781/7316/10213/4085/55166/5715/5701/5685/8815/5686/79003/9126/9232/23592/9700/5527/5716/701/57551/5693/5721 190 Human_herpesvirus_1 R-HSA-68882 Mitotic Anaphase 189/6371 201/10654 3.12370479095794e-29 1.837779652013588e-27 7.06943715848376e-28 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/5520/81027/51529/4001/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/221496/7444/5698/5692/5713/91687/119504/11243/10376/5710/7324/83540/2010/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/5708/347733/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/7443/112714/1781/7316/10213/4085/55166/5715/5701/5685/8815/5686/79003/9126/9232/23592/9700/5527/5716/701/57551/5693/5721 189 Human_herpesvirus_1 R-HSA-68877 Mitotic Prometaphase 188/6371 200/10654 4.968812906076205e-29 2.8063855293518406e-27 1.0795399829622409e-27 114791/10844/55839/11130/440145/6249/9735/7531/1459/11190/203068/5526/54801/51807/9212/347688/10274/1460/147841/348995/79441/10381/57122/5116/1780/23122/5048/57405/8655/1457/23279/9702/2491/7846/7840/1060/11064/81027/11004/9184/5518/55835/29922/23332/25909/10726/81930/55746/93323/5515/79682/10403/64151/25936/55869/1454/3619/64105/332/10051/5528/983/79902/3796/79959/5519/81565/80097/91687/11243/10376/23397/10540/85378/83540/7514/54930/54820/113130/6396/1453/27229/64946/9793/140735/220134/84617/4928/5903/11258/22981/55055/8636/80776/1783/401541/7532/55125/10382/79172/121441/7277/9133/79980/6232/23047/9814/653784/5885/23354/891/5501/9738/1639/55722/4957/5566/54821/9183/1062/699/7283/347733/22919/8243/10426/5529/22994/51143/1069/5577/10383/5347/84790/84643/80184/22897/5108/10592/7280/10806/1778/5516/115106/4926/5905/22995/55559/81929/54908/55143/5525/10142/1058/991/79019/348235/80152/1063/8379/95681/23244/23421/55920/79023/10735/112714/1781/80321/4085/55166/10121/84131/3320/79003/9126/9918/10733/4751/5527/27175/80254/701/57551/9662/55142/8481/55755 188 Human_herpesvirus_1 R-HSA-162906 HIV Infection 214/6371 233/10654 6.92346809079394e-29 3.759975747769632e-27 1.4463601355666694e-27 6884/23165/6875/5689/2237/7852/162/5682/27243/6874/1174/348995/143471/57122/5705/3981/5431/23511/5435/5709/9978/5433/5695/2960/292/567/51271/23279/5711/23327/29082/8732/23225/5683/2965/2534/27183/5699/5439/5702/6873/3836/163/9972/6881/2967/51616/8021/11198/904/55690/51497/5062/55746/5696/5691/92421/7314/5879/5718/137492/8945/51606/161/25978/5700/51160/122706/5707/2959/10053/7518/23198/404672/10015/91782/5438/3978/10762/79720/4836/926/9397/9861/79902/11168/9883/89853/83860/5698/5692/5713/5710/2068/5902/5478/5719/6233/7514/1025/3932/6396/129401/6883/7936/1175/6829/8907/2957/940/25920/60489/1173/4928/2963/5434/5903/55706/7175/79643/5436/6878/4869/5706/160/293/920/4331/5714/4927/8148/2966/2962/5688/54457/8812/5687/5708/128866/905/2071/5901/8086/5704/7311/93343/6880/6908/7251/8905/5694/1104/2547/6882/2961/5432/22916/1234/6877/5905/3837/6917/81929/5440/164/5684/8065/5720/902/9631/3159/5430/5690/7520/5717/9491/6500/6749/79023/5441/23636/10197/7469/919/130340/4686/7316/10213/6872/53371/3055/9688/8731/6879/9150/5715/9525/5701/2958/5437/5685/8815/5686/6827/2968/5716/375/138474/1022/5693/5721/8178/8480/291 214 Human_herpesvirus_1 R-HSA-5633007 Regulation of TP53 Activity 155/6371 160/10654 1.1047735677561826e-28 5.77755658396937e-27 2.2224684637902154e-27 6884/6875/5563/83990/64769/9156/1763/1459/7486/6874/133383/9212/5982/1460/11200/472/53632/79813/639/28996/84289/1457/6790/29117/4194/5928/1432/4683/56950/84126/1107/8900/6873/5371/2475/672/6881/51616/5518/6117/11198/7159/51230/83695/7314/5515/1263/23368/23774/6118/3622/6446/51422/117584/116028/890/983/5519/27154/5458/83860/57459/10000/5985/900/7994/3066/7157/5984/6233/10419/5600/6883/7874/5608/5884/5810/26155/26013/253260/5170/80010/7862/1029/5457/9219/8445/204851/6878/5931/580/11073/80196/54971/641/1108/8148/64223/6119/3364/5571/10524/54457/144715/1616/6794/54815/94241/1111/8626/208/79109/7311/7161/5562/6880/6908/5983/5564/6882/5565/1020/53615/6877/5516/1017/9891/5305/5883/25946/10111/207/22974/6749/545/8550/7316/6872/55615/6879/112858/10848/9099/2033/3065/91875/5527/5932/8851/5300/7156/138474/133746/10919/4193 155 Human_herpesvirus_1 R-HSA-2467813 Separation of Sister Chromatids 179/6371 190/10654 4.8567056790698515e-28 2.4491672924452252e-26 9.42127868571445e-27 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/81027/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/5698/5692/5713/91687/119504/11243/10376/5710/7324/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/5708/347733/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7280/1778/5516/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/112714/1781/7316/10213/4085/55166/5715/5701/5685/5686/79003/9126/9232/9700/5527/5716/701/57551/5693/5721 179 Human_herpesvirus_1 R-HSA-69206 G1/S Transition 129/6371 131/10654 1.3299971802773076e-26 6.475710408798477e-25 2.4910292015357198e-25 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/4998/5711/5928/10926/5683/990/5699/5702/8900/55388/28227/5518/6117/5001/7465/5558/5696/5691/7314/5515/6241/5718/6118/23594/7027/5700/5707/898/91768/5934/5557/993/890/1876/983/9861/5519/6502/5698/10000/5692/5713/595/4175/5710/5719/6233/7298/23649/1719/1163/4999/4172/26271/1019/5000/8318/54107/4173/5706/286826/891/4331/5714/5111/51053/6119/5688/5687/91750/5427/5708/1874/81620/208/5704/29935/55957/23595/7311/5694/4176/5516/56655/1017/5684/5720/902/8317/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5933/5426/4171/5715/5701/5685/5686/3065/5716/1022/5693/5721/7083/132660 129 Human_herpesvirus_1 R-HSA-6798695 Neutrophil degranulation 393/6371 480/10654 2.0984196823839167e-26 9.876561971753636e-25 3.799244056526671e-25 5869/8773/7130/9798/1727/5689/8804/5777/8514/5806/4893/9218/4790/5273/3240/960/7305/1823/1511/5657/57826/1915/3107/203068/5175/5199/383/654364/8836/2268/5211/5908/1460/29108/23385/54509/6280/5788/535/10577/5912/10312/5709/5269/10576/1509/5695/2896/4126/8655/567/290/7133/154664/3106/3074/3417/3043/388698/1667/2548/2204/1432/11010/3920/5476/8904/5683/929/201294/2588/3482/4311/80142/2444/23200/5702/566/9961/51552/10075/56729/10487/684/6709/6093/160364/441864/8826/9522/4282/3608/2720/3312/387263/2665/4758/1654/967/2519/6037/5879/51316/2717/1992/5718/3303/58485/2934/80331/6518/161/56888/3579/94103/5707/2358/3848/8972/823/427/353189/5594/4831/4680/5787/6727/127829/7414/258010/10533/55754/4257/51209/326624/847/3683/2517/25852/3934/22918/8895/5834/9545/1315/102/84443/4069/5317/965/4973/9861/5870/410/6556/411/226/2821/199675/978/55832/968/23601/5713/1/2495/3728/3614/10043/4125/5478/5719/374395/5328/728/11001/5580/23191/3685/302/634/1729/9145/6036/1535/64114/2040/230/317/23250/2990/401258/5663/7879/8907/671/2992/1508/28956/30/10450/25801/1828/3903/23352/23412/7276/5284/83858/4332/10159/1938/8635/51125/1650/338339/3684/79888/387921/3163/54472/101/3577/79169/55860/1378/10549/2760/5864/4318/3958/963/79980/23317/5836/53917/6993/11240/6616/5329/966/5611/84061/1116/527/6279/6515/54918/11322/4048/353/6286/5337/210/10092/170482/5795/6793/197/140885/2171/3310/1832/5708/55313/3615/11314/138050/23218/820/51143/4860/6386/10788/6402/5473/3326/10857/55004/10097/3916/53831/10383/387/81619/10396/196527/79930/5049/51806/80184/3304/2547/8673/10493/1075/53916/6282/114790/22931/1778/10694/2512/3837/10890/5036/8621/5005/29099/327/11333/5315/8876/23197/1991/10120/6317/7520/5717/2919/5004/221/9725/1604/2357/10213/4718/6278/5547/5799/932/1522/2799/5768/1471/9588/29952/7415/3146/4353/5701/9342/6836/8649/5265/3320/5686/388697/23593/391/175/25798/5873/1088/57126/150372/26578/1143/5878/2683/8566/11031/22875/948/945/1675/7226/719/93100/47/79895/5906/89777/100049587/81567/10855/3687/353376/124583/84418/7097/5660/2212/1536/8987/10970/3689/961/2207/5724/51382/2950/718 393 Human_herpesvirus_1 R-HSA-168254 Influenza Infection 149/6371 155/10654 2.2421570803929427e-26 1.0212663862951082e-24 3.928533288566242e-25 3839/6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/116832/23225/6156/6143/5439/3836/6139/9972/3921/8021/7040/55746/6208/6170/3303/6203/402569/6147/6222/8106/9636/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/7514/1213/5610/1211/6188/6396/129401/200916/6122/6230/4928/2963/3838/5434/5903/6194/55706/7175/6166/5436/6136/3841/6125/821/6232/6160/293/5611/6193/4927/6210/6229/6205/2962/10898/3840/140801/6235/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/81929/5440/9349/4736/51121/9631/6159/6217/3843/5430/6152/51065/6141/79023/6123/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 149 Human_herpesvirus_1 R-HSA-69306 DNA Replication 125/6371 127/10654 1.0094994667562887e-25 4.454416397062124e-24 1.7134925159415955e-24 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/143471/5705/5709/5422/9978/1869/4174/5695/84515/4998/5711/10926/5683/990/5699/5702/8900/51529/29945/51434/55388/6117/29882/5001/10714/5558/5696/5691/7314/996/5718/6118/23594/5700/122706/5707/64785/23198/898/3978/5557/890/51433/9861/6502/5698/5692/5985/5713/119504/4175/5710/5984/7324/5719/64682/6233/23649/5424/4999/4172/5000/8318/246184/54107/4173/5706/8881/5425/5714/5111/51053/6119/5688/5687/5427/5708/81620/10393/1870/5704/29935/51343/23595/7311/25906/51659/5983/5694/4176/56655/1017/5684/5720/57804/8317/9837/5690/5717/9491/6500/10197/7316/10213/5426/4171/1871/5715/5701/5685/5686/5716/5981/5693/5721 125 Human_herpesvirus_1 R-HSA-8856828 Clathrin-mediated endocytosis 141/6371 146/10654 1.0590547290981083e-25 4.5314705378379664e-24 1.7431331426303792e-024 5869/374/85439/71/8674/5286/4738/7039/1212/23208/1785/29763/950/8871/10094/554/54874/55738/10980/22848/7037/2017/3482/408/9322/10987/6456/185/8976/30011/2885/163/11037/1759/23149/3312/29993/9185/7314/9856/1839/161/7018/25977/5868/10618/10093/8027/1856/9892/8322/2060/2069/1601/6453/55707/8301/1129/9146/6455/4074/10920/26119/29979/6233/90019/7474/6844/1213/2580/1211/29924/4036/255324/1175/85021/10109/6869/1173/6857/84251/23048/9026/29988/409/112574/382/160/338/8218/920/22905/26052/8867/10092/9829/2873/10097/7311/1956/60/8533/274/51429/8673/3092/50618/51138/9318/685/127833/1080/29978/58513/7316/1950/273/64708/10552/26130/3267/3949/867/9341/915/917/6572/115548/5878/1861/10096/143425/3575/6845/551/154/10254/6457/50813/4952/11252 141 Human_herpesvirus_1 R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 130/6371 134/10654 2.0141012710690103e-24 8.364444102204243e-23 3.217573547590122e-23 5295/8454/5689/3725/4893/5335/4790/5682/5291/7321/143471/5705/5530/5709/5695/4792/5711/5683/2534/5699/5702/2885/9846/3845/7334/3265/3551/5062/5696/5691/7314/5879/7294/257397/5718/8945/5601/4773/5290/5700/122706/5707/5336/5594/4214/23198/23118/10892/8517/10125/5970/9861/5588/5698/5692/5713/5710/10454/5719/6233/7410/7409/3702/2353/115727/801/805/5170/6464/2205/387522/4772/3937/4775/10451/5706/2206/6850/8915/5714/5688/5687/4067/5708/5602/695/7189/6654/5704/7006/7311/5694/5058/6416/997/5595/1147/9402/5684/5720/6885/84433/5690/5532/5717/9491/6500/3708/10197/7316/10213/7335/10768/7322/5715/5701/27040/23291/5685/5686/5534/5609/5716/10235/5296/808/5599/5693/5721/2207 130 Human_herpesvirus_1 R-HSA-168255 Influenza Life Cycle 138/6371 144/10654 4.520752056031237e-24 1.823800543747459e-22 7.015663341089078e-23 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/116832/23225/6156/6143/5439/3836/6139/9972/3921/8021/55746/6208/6170/3303/6203/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/7514/1213/1211/6188/6396/129401/200916/6122/6230/4928/2963/5434/5903/6194/55706/7175/6166/5436/6136/6125/821/6232/6160/5611/6193/4927/6210/6229/6205/2962/140801/6235/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/81929/5440/9349/4736/51121/9631/6159/6217/3843/5430/6152/51065/6141/79023/6123/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 138 Human_herpesvirus_1 R-HSA-69239 Synthesis of DNA 117/6371 119/10654 5.763148441983317e-24 2.260434888911234e-22 8.695276596676584e-23 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/143471/5705/5709/5422/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/6117/29882/5001/10714/5558/5696/5691/7314/996/5718/6118/23594/5700/122706/5707/64785/23198/898/3978/5557/890/51433/9861/6502/5698/5692/5985/5713/119504/4175/5710/5984/7324/5719/64682/6233/23649/5424/4999/4172/5000/8318/246184/54107/4173/5706/8881/5425/5714/5111/6119/5688/5687/5427/5708/81620/10393/5704/51343/23595/7311/25906/51659/5983/5694/4176/56655/1017/5684/5720/57804/9837/5690/5717/9491/6500/10197/7316/10213/5426/4171/5715/5701/5685/5686/5716/5981/5693/5721 117 Human_herpesvirus_1 R-HSA-6807070 PTEN Regulation 134/6371 140/10654 3.0809025396616566e-23 1.1757390232438539e-21 4.522747398194637e-22 1912/5689/3725/6591/5682/1822/1459/9112/6045/27327/80012/1460/143471/5705/5709/5695/1457/1911/4734/11060/5711/5928/10325/5683/23512/57332/5699/2444/5702/192669/1107/8975/5371/2475/1386/10670/4343/64121/5696/5691/7314/5718/23186/5700/122706/5707/2146/51564/5594/84232/23198/9861/7101/81847/84733/57459/5698/10000/5692/5713/5710/3066/7157/5719/6233/331/8726/26523/7874/57521/23608/6015/28956/389541/9219/8535/5931/58528/5706/8658/5714/1108/2122/64223/10014/5688/5687/5708/54815/6009/208/5704/55004/57504/7311/648/5694/23466/53615/5595/27161/5684/8841/5720/5468/5978/10273/207/5690/57690/5717/9491/10197/192670/153129/7316/10213/57167/5715/1958/5701/5685/8649/5686/5728/6615/3065/23028/5987/23112/10542/5716/5693/5721 134 Human_herpesvirus_1 R-HSA-376176 Signaling by ROBO receptors 195/6371 218/10654 8.416101679871826e-23 3.127246203152373e-21 1.2029663342974688e-21 6158/5689/6138/6227/7852/6206/6234/6191/6128/5682/6132/57522/10298/6129/6176/5578/9353/6224/6146/6154/26986/143471/6202/5705/6169/23122/5709/6175/9978/6218/5695/65109/6173/6167/5711/116832/1605/5683/6156/5699/6143/9495/5702/6139/10487/8440/3921/23332/5062/6208/5696/6170/5691/7314/5879/6387/5718/25/6203/8861/6147/5700/122706/5707/5567/89884/6222/23198/27/26019/2935/6134/6091/22794/6155/4116/6714/6231/9861/6142/23521/10486/5698/5692/5713/1981/5710/6207/5719/6233/6188/200916/6122/6230/6194/2107/6166/56924/6136/5568/6125/5706/6232/6160/55110/5714/6193/6210/6229/6205/5566/4650/5688/5687/5708/23767/5063/140801/6235/6181/998/9939/6654/5704/7311/6223/25873/387/6655/23708/5694/5058/9045/6187/65110/6168/22916/6157/6137/10921/6144/55740/23032/5684/9349/4736/5720/51121/2817/6159/4690/6217/8022/6152/5690/5532/5717/9491/51065/6141/23053/6123/10197/6164/4686/7316/10213/5216/6209/11224/6165/6130/5715/6204/5701/6228/5576/5685/51466/5686/7408/6124/8453/5716/23380/1630/6189/9775/6135/6201/6161/5693/5721/6133/9901 195 Human_herpesvirus_1 R-HSA-72613 Eukaryotic Translation Initiation 116/6371 119/10654 1.5583307792503866e-22 5.500907650753864e-21 2.1160491634031564e-21 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/116832/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/1978/200916/6122/1968/6230/8669/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/8893/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/8891/51121/6159/6217/6152/51065/6141/10480/6123/1967/6164/8661/9669/6209/1964/11224/6165/6130/8890/6204/6228/6124/3646/6189/6135/6201/6161/8892/6133 116 Human_herpesvirus_1 R-HSA-72737 Cap-dependent Translation Initiation 116/6371 119/10654 1.5583307792503866e-22 5.500907650753864e-21 2.1160491634031564e-21 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/116832/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/1978/200916/6122/1968/6230/8669/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/8893/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/8891/51121/6159/6217/6152/51065/6141/10480/6123/1967/6164/8661/9669/6209/1964/11224/6165/6130/8890/6204/6228/6124/3646/6189/6135/6201/6161/8892/6133 116 Human_herpesvirus_1 R-HSA-168273 Influenza Viral RNA Transcription and Replication 128/6371 134/10654 5.419407142199128e-22 1.8663909475085777e-20 7.17949700994801e-21 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/116832/23225/6156/6143/5439/6139/9972/3921/8021/55746/6208/6170/6203/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/6188/6396/129401/200916/6122/6230/4928/2963/5434/5903/6194/55706/7175/6166/5436/6136/6125/6232/6160/5611/6193/4927/6210/6229/6205/2962/140801/6235/6181/8086/7311/6223/25873/9045/6187/5432/6168/6157/6137/6144/81929/5440/9349/4736/51121/9631/6159/6217/3843/5430/6152/51065/6141/79023/6123/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 128 Human_herpesvirus_1 R-HSA-927802 Nonsense-Mediated Decay (NMD) 112/6371 115/10654 1.1315308215165796e-21 3.715631441817234e-20 1.429302090336732e-20 6158/9887/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/55629/6169/6175/6218/65109/6173/6167/116832/6156/6143/5520/6139/23381/5518/3921/6208/6170/5515/6203/6147/6222/26019/2935/6134/22794/6155/4116/6231/6142/23521/1981/6207/6233/6188/23049/5976/200916/6122/6230/6194/2107/6166/56006/6136/6125/6232/6160/55110/6193/6210/6229/6205/55181/140801/6235/6181/9939/7311/6223/25873/23708/9045/6187/65110/6168/22916/6157/6137/10921/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/4686/6209/11224/6165/6130/6204/6228/55802/6124/6189/23293/9775/6135/6201/6161/6133 112 Human_herpesvirus_1 R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 112/6371 115/10654 1.1315308215165796e-21 3.715631441817234e-20 1.429302090336732e-20 6158/9887/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/55629/6169/6175/6218/65109/6173/6167/116832/6156/6143/5520/6139/23381/5518/3921/6208/6170/5515/6203/6147/6222/26019/2935/6134/22794/6155/4116/6231/6142/23521/1981/6207/6233/6188/23049/5976/200916/6122/6230/6194/2107/6166/56006/6136/6125/6232/6160/55110/6193/6210/6229/6205/55181/140801/6235/6181/9939/7311/6223/25873/23708/9045/6187/65110/6168/22916/6157/6137/10921/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/4686/6209/11224/6165/6130/6204/6228/55802/6124/6189/23293/9775/6135/6201/6161/6133 112 Human_herpesvirus_1 R-HSA-8957275 Post-translational protein phosphorylation 106/6371 108/10654 1.4673927642953297e-21 4.708996779965922e-20 1.811422646833469e-20 56955/4240/3270/9210/10272/2153/7857/29106/91851/6696/51156/1435/265/11098/10130/2200/80341/375056/1114/720/10117/3956/3569/54972/2519/8720/7018/10618/11167/813/5179/8074/51246/348/4924/3484/102/8614/336/6694/4148/174/57104/721/2335/7466/116519/2266/51280/7076/2243/84141/3488/8542/4221/351/4052/7184/56975/334/3912/338/64856/335/5611/197/3053/3895/5624/1000/54757/8404/255738/3913/652/57719/147111/2719/3487/3371/54587/401138/3486/7425/6383/3827/3490/5589/2621/3915/5768/1471/1462/10232/462/3698/5265/1758/258/11320/5954/213/10970/5034/1356/718 106 Human_herpesvirus_1 R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 109/6371 112/10654 4.990072791061707e-21 1.5657739513286956e-19 6.023105403948166e-20 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/6202/6169/6175/6218/6173/6167/116832/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/200916/6122/1968/6230/8669/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/9669/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 109 Human_herpesvirus_1 R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 108/6371 111/10654 8.178258703114798e-21 2.456957721020871e-19 9.45124633999381e-20 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/116832/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/200916/6122/1968/6230/8669/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 108 Human_herpesvirus_1 R-HSA-5696398 Nucleotide Excision Repair 108/6371 111/10654 8.178258703114798e-21 2.456957721020871e-19 9.45124633999381e-20 2074/10445/5982/6613/7507/5431/5435/9978/5433/85015/10980/57654/2965/5439/10987/2067/2967/6612/6117/7334/10714/91603/7314/6118/83444/404672/9557/3150/86/5438/3978/1643/29844/5985/10920/2068/5984/6233/93973/8607/7874/5424/5886/8451/8554/10450/5434/5436/7515/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/142/125476/2071/1069/7329/51426/2873/7311/3980/60/8533/5983/10038/5432/51138/7528/56655/9318/6917/5440/902/27339/5430/57804/5441/7336/2072/54778/7316/64708/5426/283899/7341/5437/79913/10401/54617/2033/2968/56949/5887/9716/2073/5981/57461/1022/8178/50813/7508 108 Human_herpesvirus_1 R-HSA-8856688 Golgi-to-ER retrograde transport 126/6371 133/10654 1.0984502140986591e-20 3.231274379806889e-19 1.2429831370063774e-19 11014/64837/11127/51807/53407/347688/3798/5861/10381/1780/5048/8655/84516/832/285643/55738/10112/636/64147/7846/2590/51226/81027/11004/10749/81930/54732/51164/60561/113220/3797/29127/55605/23299/377/1315/3796/5870/124602/11316/55614/89953/56992/8729/23423/10376/1314/10540/3835/147700/3833/378/9493/26286/26958/140735/10959/3831/84364/22820/84617/11258/1783/55850/9585/10382/93661/55860/830/3832/7277/10671/9554/23303/1639/8775/26153/81876/9183/1062/11015/146909/347733/662/90990/51143/23046/10383/24137/84790/84643/10945/5049/51594/22920/7280/829/22931/1778/55582/5321/9371/51014/23095/5050/63908/112714/1781/22930/25782/10121/6836/547/51560/8774/10972/381/4905/3834/9276/55083/3799/375/221458/22818/372 126 Human_herpesvirus_1 R-HSA-9010553 Regulation of expression of SLITs and ROBOs 156/6371 171/10654 1.413081094319573e-20 4.0719806228147693e-19 1.5663799026184741e-19 6158/5689/6138/6227/6206/6234/6191/6128/5682/6132/6129/6176/9353/6224/6146/6154/26986/143471/6202/5705/6169/5709/6175/9978/6218/5695/65109/6173/6167/5711/116832/1605/5683/6156/5699/6143/5702/6139/3921/6208/5696/6170/5691/7314/5718/6203/8861/6147/5700/122706/5707/89884/6222/23198/26019/2935/6134/6091/22794/6155/4116/6231/9861/6142/23521/5698/5692/5713/1981/5710/6207/5719/6233/6188/200916/6122/6230/6194/2107/6166/6136/6125/5706/6232/6160/55110/5714/6193/6210/6229/6205/5688/5687/5708/140801/6235/6181/9939/5704/7311/6223/25873/23708/5694/9045/6187/65110/6168/22916/6157/6137/10921/6144/23032/5684/9349/4736/5720/51121/6159/6217/8022/6152/5690/5717/9491/51065/6141/23053/6123/10197/6164/4686/7316/10213/6209/11224/6165/6130/5715/6204/5701/6228/5685/5686/6124/8453/5716/6189/9775/6135/6201/6161/5693/5721/6133 156 Human_herpesvirus_1 R-HSA-69620 Cell Cycle Checkpoints 247/6371 293/10654 2.779224915915668e-20 7.848531162545846e-19 3.019115908657863e-19 5689/55839/11130/9134/83990/11065/6249/5682/9156/57060/9735/1763/7531/7486/7321/5526/10971/8697/9212/5982/7533/2810/147841/348995/11200/143471/472/57122/5705/1780/23122/5048/5709/4174/5695/57405/8655/84515/23279/4194/4998/5711/2491/4683/10926/5683/990/1060/165918/84126/5699/5702/8900/51529/29945/8924/11004/51434/55388/672/9184/5518/6117/29882/7334/5001/23332/7465/25909/51230/10726/81930/55746/5696/83695/5691/7314/996/5515/5718/6118/79682/10403/23594/25936/5700/122706/5707/51588/51720/3619/23198/63967/898/64105/7534/332/5528/993/116028/890/983/51433/9861/79902/3796/9656/5519/81565/5698/5692/5985/5713/91687/119504/11243/4175/5710/7157/5984/7324/83540/5719/64682/6233/7514/7158/54820/6396/64946/9793/5884/5810/140735/4999/220134/4172/80010/4928/5903/5000/8318/246184/55055/51512/1029/80776/1783/401541/7532/79172/4173/5706/9133/79980/6232/580/8881/11073/891/5501/641/5714/54821/6119/9183/3364/10524/5688/1062/699/5687/144715/5708/22919/5529/51143/1111/10393/5704/23595/7311/25906/5347/84643/5983/5694/4176/7529/1778/5516/1017/5905/81929/5684/5720/54908/55143/5883/5525/25946/1058/991/79019/10111/8317/348235/80152/5690/1063/8379/5717/1027/9491/23421/545/55920/79023/10197/7336/29086/1781/7316/10213/4085/1026/4171/55166/5715/9088/7341/5701/5685/5686/995/79003/5527/5716/701/5932/9025/79184/57551/7156/5693/5721/4193 247 Human_herpesvirus_1 R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 105/6371 108/10654 3.593505638067882e-20 9.94907835480755e-19 3.8271391315645565e-19 5295/3605/7124/2308/1052/7291/356/3593/246/9021/6624/3082/5743/3091/10538/3383/6097/6657/3576/3662/3688/4985/7133/3606/4609/4988/3717/2162/6347/7040/3312/3569/4692/3596/3598/3592/7412/4582/6367/4312/6778/332/4313/3565/3934/3976/5443/3718/149233/598/2247/2335/595/7157/2353/604/7076/51561/3570/7297/9655/3566/7184/3684/4318/3726/58480/301/6774/6772/8651/1901/3552/79923/112744/3716/6356/5008/3586/6095/596/2208/2309/3561/207/5292/5451/7422/3553/2625/3597/4314/1026/3320/4843/6288/948/6935/3687/7431/3929/3162/1278/4170/3689 105 Human_herpesvirus_1 R-HSA-2219528 PI3K/AKT Signaling in Cancer 99/6371 101/10654 4.912296371370097e-20 1.3338773993028032e-18 5.131062606532328e-19 5295/2308/374/2250/5291/7039/3082/941/2064/145957/2534/9965/2264/9542/2885/2475/8660/2252/2253/5879/1839/5290/3667/8823/2065/3815/2069/84335/8074/7249/2260/2249/6714/2099/2248/2932/2247/5880/10000/7409/2246/2251/5154/3932/2931/118788/255324/5781/940/253260/5170/572/4303/930/6199/2263/4233/64223/8503/5159/29851/3084/208/9365/10718/79109/5293/1956/2549/1147/8822/685/2309/842/207/1027/8817/2100/2254/152831/1950/1026/55615/26281/10818/2261/2255/3164/391/5728/2066/27006/942/1385/5155/4254/5296/5156/4193 99 Human_herpesvirus_1 R-HSA-162909 Host Interactions of HIV factors 122/6371 129/10654 7.125093923472372e-20 1.898232569800564e-18 7.301983047689661e-19 23165/5689/162/5682/1174/348995/143471/57122/5705/23511/5709/9978/5695/292/567/23279/5711/23225/5683/2534/5699/5702/3836/163/9972/8021/904/55690/5062/55746/5696/5691/7314/5879/5718/8945/51606/161/5700/122706/5707/10053/23198/10762/926/9861/79902/11168/9883/5698/5692/5713/5710/5902/5478/5719/6233/7514/1025/3932/6396/129401/1175/8907/940/60489/1173/4928/5903/55706/7175/4869/5706/160/293/920/5714/4927/5688/5687/5708/5901/8086/5704/7311/8905/5694/1104/5905/3837/81929/164/5684/8065/5720/9631/3159/5690/5717/9491/6500/79023/23636/10197/919/130340/7316/10213/53371/3055/9688/5715/5701/5685/8815/5686/5716/375/5693/5721/8480/291 122 Human_herpesvirus_1 R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 91/6371 92/10654 1.395652406090054e-19 3.649372587776216e-18 1.4038141160671891e-18 6884/6875/5563/83990/9156/1763/1459/7486/6874/9212/5982/1460/11200/472/53632/28996/1457/6790/4194/1432/4683/84126/8900/6873/672/6881/51616/6117/11198/83695/7314/1263/6118/51422/116028/890/83860/5985/7157/5984/6233/5600/6883/5884/5810/26155/80010/8445/204851/6878/580/11073/641/8148/6119/3364/5571/10524/54457/144715/6794/94241/1111/7311/5562/6880/6908/5983/5564/6882/5565/1020/6877/1017/9891/5883/10111/22974/6749/545/8550/7316/6872/6879/112858/5932/8851/5300/7156/138474/4193 91 Human_herpesvirus_1 R-HSA-69052 Switching of origins to a post-replicative state 89/6371 90/10654 3.862553335023995e-19 9.916227834643419e-18 3.81450243229164e-18 8454/5689/9134/11065/5682/7321/8697/143471/5705/5709/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/29882/5001/5696/5691/7314/996/5718/23594/5700/122706/5707/23198/898/890/51433/9861/6502/5698/5692/5713/119504/4175/5710/7324/5719/64682/6233/4999/4172/5000/246184/4173/5706/8881/5714/5688/5687/5708/81620/10393/5704/51343/23595/7311/25906/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 89 Human_herpesvirus_1 R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 118/6371 125/10654 4.585285220612533e-19 1.1561469163401601e-17 4.447381905706893e-18 56955/4240/3270/9210/10272/2153/1511/7857/29106/91851/6696/51156/1435/265/11098/10130/2200/80341/375056/1114/720/10117/3956/3569/54972/2519/8720/7018/5340/10618/11167/813/5179/8074/4312/51246/348/4924/4313/3484/102/8614/336/6694/5069/4148/174/57104/721/2335/7466/116519/2266/51280/7076/2243/60676/84141/3488/2147/8542/4221/351/4052/7184/56975/334/3912/338/64856/335/5611/197/3053/3895/5624/1000/54757/3481/8404/255738/3913/354/652/57719/147111/2719/3487/3371/54587/3485/3489/401138/3486/7425/6383/3827/3490/5589/2621/3915/5768/1471/1462/10232/462/3698/5265/1758/258/11320/5954/3479/213/10970/5034/1356/718 118 Human_herpesvirus_1 R-HSA-8868773 rRNA processing in the nucleus and cytosol 172/6371 195/10654 9.803992877336145e-19 2.428638235578708e-17 9.342309002226133e-18 6158/5393/6138/6227/6206/6234/6191/6128/6132/6129/23404/55226/6176/10528/84135/27340/27043/6224/6146/6154/88745/6202/51096/6169/55272/6175/6218/5394/6173/6167/28987/116832/23481/51077/6156/117246/6143/6139/79159/23160/26168/11340/3921/10607/11103/51388/6208/6170/22984/10813/9136/6203/51504/23246/54433/6147/8568/27292/6222/1454/56902/51602/6134/6155/6231/6142/23521/54555/10171/5822/6207/10969/10556/6233/6188/79707/54881/1453/4691/23016/118460/200916/6122/6230/2091/55651/55127/6194/6166/10436/8780/9277/84128/6136/6125/4839/6232/90459/134430/6160/92856/65083/6193/10200/6210/6229/6205/115939/11056/9790/55131/140801/6235/55720/6181/55759/705/7311/6223/25873/55505/51010/26354/56915/51202/9045/6187/6168/6157/6137/79050/22894/84946/6144/9349/55813/4736/57418/22803/51121/6159/25879/6217/81887/6152/57050/51065/6141/6123/55781/6164/6209/11224/6165/6130/6204/1736/6228/10438/10199/51013/6124/25926/83732/6189/6135/6201/6161/54512/10885/6133/9188 172 Human_herpesvirus_1 R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 87/6371 88/10654 1.068198684484542e-18 2.6005112801589195e-17 1.000345773491876e-17 5393/5689/5682/23404/5578/26986/143471/5705/5709/5695/5711/1432/5683/5699/5702/11340/8021/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/7534/9261/8741/9861/5698/5692/5713/1981/5710/5719/6233/5580/7514/5600/8570/23016/118460/1994/5073/3842/3315/5706/8125/677/7538/5714/5688/5687/5708/5704/7311/51010/5694/56915/3304/6418/167227/7529/22894/5684/5720/207/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/55802/51013/5716/54464/5693/54512/5721 87 Human_herpesvirus_1 R-HSA-72689 Formation of a pool of free 40S subunits 98/6371 101/10654 1.1234822633755425e-18 2.688740603197061e-17 1.0342851880495629e-17 6158/6138/6227/6206/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/8663/23521/6207/6233/51386/6188/200916/6122/6230/8669/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/8664/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 98 Human_herpesvirus_1 R-HSA-983705 Signaling by the B Cell Receptor (BCR) 107/6371 112/10654 1.4114417972765152e-18 3.321593029590733e-17 1.2777262585871614e-17 5295/8454/5689/5777/4893/4790/5579/5682/84876/143471/5705/5530/5709/5695/4792/5711/5683/2534/5699/5702/30011/2885/4794/3845/3265/3551/973/5696/5691/7314/6786/5718/8945/4773/5966/80228/5700/122706/5707/5336/23198/10892/8517/10125/5970/25780/9861/5698/5692/5713/5710/2280/5478/5719/6233/7409/118788/801/805/4772/4775/930/5706/6850/8915/5714/5688/5687/4067/29760/5708/695/6654/5704/7311/5293/27071/5694/1147/5684/5720/6885/4690/640/84433/5690/5532/5717/9491/6500/3708/10197/7316/10213/10768/4793/5715/5701/23291/5685/5686/5534/974/5716/808/5693/5721 107 Human_herpesvirus_1 R-HSA-418594 G alpha (i) signalling events 324/6371 406/10654 1.6670753356410954e-18 3.858869465451191e-17 1.484401851925462e-17 729230/2788/10316/1880/7852/50833/29899/2339/6385/5331/5726/338442/64805/2770/817/1237/2550/5578/3000/50832/3354/2841/5582/4987/51289/259294/8644/2912/3576/6360/5530/4985/2920/2921/1236/259295/107/6010/9568/2840/2831/145226/5367/4988/6370/58191/5475/6755/1524/151056/643/221914/2782/5499/339403/4023/2914/8843/2847/2833/10636/9290/5518/9170/6382/187/6121/6750/6004/259296/259289/5998/50835/2587/53829/814/2773/5515/2787/6387/54884/6368/818/4544/5947/4543/126006/10663/4889/9283/727/338398/344/117579/3579/345/375790/23566/2358/5567/2916/259293/5594/5179/10681/5142/112/8811/5573/348/56923/2832/5528/27199/2826/6376/165140/27198/111/5443/4836/3627/2792/9397/54429/6714/336/3361/6346/10988/5519/134/5588/1129/51083/2785/2783/2784/1233/2262/6366/5613/2861/2771/728/183/10022/5580/6373/57121/1132/1814/80835/4036/5153/6357/50700/196883/9672/115/8698/5999/801/9934/50840/2791/50865/805/10803/2913/3838/7276/351/11251/3352/8484/6351/6752/2781/1903/84539/6753/5568/3577/2918/5368/6754/8862/301/56670/150/113/338/335/2853/6751/186/53637/10645/5566/84254/10563/5540/1901/5733/23236/256933/10850/624/4852/816/8601/2786/50838/5577/5473/4283/2239/11255/10874/83756/51109/29967/611/2719/56477/1020/259286/3350/129521/1234/109/5516/151/57007/5533/815/9249/26086/5321/9294/54331/283869/2817/5575/59345/63940/4986/6374/5539/259287/2852/50836/3339/1230/5532/846/4886/2919/51764/94235/114/3708/259290/57016/6383/108/26020/5196/2779/3827/5173/2357/55970/2778/6352/140/10768/346562/152/5957/6364/80834/259292/3949/2793/5030/5697/5576/3355/5534/3351/4035/6288/6372/50834/259285/79823/1385/7804/5144/719/6363/2917/1268/50831/2359/50839/808/5660/1815/1325/64407/1232/1902/50837/10082/5137/1269/59340/4887/2790/718/623 324 Human_herpesvirus_1 R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 102/6371 106/10654 1.7179108347379303e-18 3.9124033849192864e-17 1.5049948908739764e-17 374/85439/8674/4738/7039/1212/23208/950/554/10980/22848/7037/3482/408/10987/6456/185/30011/2885/163/11037/23149/9185/7314/9856/1839/161/7018/25977/10618/8027/1856/9892/8322/2060/2069/1601/6453/55707/8301/1129/9146/6455/4074/10920/26119/29979/6233/90019/7474/6844/1213/1211/29924/4036/255324/1175/85021/6869/1173/6857/84251/29988/409/160/338/8218/920/22905/2873/7311/1956/8533/8673/50618/51138/9318/685/127833/1080/29978/58513/7316/1950/64708/3267/3949/867/9341/915/917/6572/115548/1861/143425/3575/6845/551/154/10254/6457/50813 102 Human_herpesvirus_1 R-HSA-5357801 Programmed Cell Death 161/6371 181/10654 1.8829473459417053e-18 4.220193099158235e-17 1.6233932005111447e-17 5689/2339/5682/4976/7531/55075/356/10971/10059/7533/2810/143471/5705/5709/1869/5695/8655/660/5711/836/5683/929/324/5699/9414/5702/90427/4001/3836/6709/6093/840/7159/26060/637/5062/5696/5691/7314/578/23368/5718/2934/11035/22985/219699/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/100506658/7082/5339/4836/5317/8797/9861/10134/999/5588/598/5698/10000/5692/708/5713/5710/3002/7157/5719/6233/5580/1613/839/8772/331/8717/57099/317/8743/140735/1828/5747/1029/572/7532/330/118/5706/1829/6774/5366/5714/8428/5688/5687/1832/56616/5708/8837/8626/197259/208/5704/7311/7161/5694/8795/3148/7529/5595/23643/4000/5533/27113/3837/596/5684/5720/7186/51765/1499/10018/842/207/5690/5717/9491/355/10197/7099/9500/7316/10213/54205/3146/5715/23604/5701/329/5685/5686/5534/4137/5716/1630/581/5599/353376/7431/5693/5721/6304/148022 161 Human_herpesvirus_1 R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 85/6371 86/10654 2.9518928468581544e-18 6.412419538098022e-17 2.4666829295203366e-17 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 85 Human_herpesvirus_1 R-HSA-453276 Regulation of mitotic cell cycle 85/6371 86/10654 2.9518928468581544e-18 6.412419538098022e-17 2.4666829295203366e-17 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 85 Human_herpesvirus_1 R-HSA-5620912 Anchoring of the basal body to the plasma membrane 95/6371 98/10654 4.8868901835888e-18 1.0338518069295659e-16 3.976945969700731e-17 79867/7531/11190/203068/54801/85302/79441/5116/5048/22832/8655/9702/132320/7846/7840/11064/84902/5518/55835/23332/93323/1454/54806/91147/983/79959/10540/117177/57545/26005/54930/54820/23322/1453/9793/4218/11258/22981/8636/54903/80776/7532/55125/10382/121441/7277/9814/23354/146057/9738/1639/55722/4957/5566/7283/22919/27077/22994/4867/1069/5577/10383/5347/80184/22897/5108/261734/57787/10806/9657/1778/115106/22995/55559/10142/51134/95681/1781/80321/8766/79598/10121/347240/84131/3320/79600/10733/4751/80254/26123/9662/55142/8481/51259/55755 95 Human_herpesvirus_1 R-HSA-69002 DNA Replication Pre-Initiation 84/6371 85/10654 4.905670755260688e-18 1.0338518069295659e-16 3.976945969700731e-17 5689/5682/143471/5705/5709/5422/1869/4174/5695/84515/4998/5711/10926/5683/990/5699/5702/55388/6117/5001/5558/5696/5691/7314/5718/6118/23594/5700/122706/5707/23198/5557/9861/5698/5692/5713/4175/5710/5719/6233/23649/4999/4172/5000/8318/54107/4173/5706/5714/51053/6119/5688/5687/5427/5708/81620/1870/5704/29935/23595/7311/5694/4176/56655/1017/5684/5720/8317/5690/5717/9491/10197/7316/10213/5426/4171/1871/5715/5701/5685/5686/5716/5693/5721 84 Human_herpesvirus_1 R-HSA-109581 Apoptosis 158/6371 178/10654 6.367021458446115e-18 1.3220932793126346e-16 5.085732310461602e-17 5689/2339/5682/4976/7531/55075/356/10971/10059/7533/2810/143471/5705/5709/1869/5695/8655/660/5711/836/5683/929/324/5699/9414/5702/90427/4001/3836/6709/6093/840/7159/26060/637/5062/5696/5691/7314/578/23368/5718/2934/22985/219699/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/100506658/7082/5339/4836/5317/8797/9861/10134/999/5588/598/5698/10000/5692/708/5713/5710/3002/7157/5719/6233/5580/1613/839/8772/331/8717/57099/317/8743/140735/1828/5747/1029/572/7532/118/5706/1829/6774/5366/5714/8428/5688/5687/1832/56616/5708/8837/8626/208/5704/7311/7161/5694/8795/3148/7529/5595/23643/4000/5533/27113/3837/596/5684/5720/7186/51765/1499/10018/842/207/5690/5717/9491/355/10197/7099/9500/7316/10213/54205/3146/5715/23604/5701/329/5685/5686/5534/4137/5716/1630/581/5599/353376/7431/5693/5721/6304/148022 158 Human_herpesvirus_1 R-HSA-9020702 Interleukin-1 signaling 99/6371 103/10654 7.293136250345883e-18 1.4862600435234494e-16 5.717237084077083e-17 8454/5689/4790/5682/8878/143471/5705/5709/9978/5695/4792/177/5711/5683/5699/5702/3654/51135/7334/3551/5696/5691/7314/257397/5718/8945/1326/11213/5700/122706/5707/8767/23198/23118/8517/5970/9861/5698/5692/5713/5710/10454/5719/6233/7850/5608/4791/3557/351/387522/54472/5706/79155/5714/64127/3552/5688/5687/5708/3656/57162/7189/5704/7311/5694/6416/3554/3556/1147/5684/5720/6885/5604/4215/10392/5690/3553/5717/9491/6500/246330/10197/4615/7316/10213/7335/4793/3146/5715/5701/23291/5685/5686/6288/6285/5716/57161/5693/5721 99 Human_herpesvirus_1 R-HSA-202403 TCR signaling 112/6371 119/10654 7.368144691688489e-18 1.4862600435234494e-16 5.717237084077083e-17 5295/8454/5689/5335/4790/5682/5291/7321/143471/5705/5788/3115/5709/5695/4792/3113/5711/3117/5683/55824/5699/5702/26191/3127/7334/3551/5062/5696/5691/7314/5718/8945/3635/5290/5700/122706/5707/8767/23198/23118/10892/8517/5970/9861/5588/5698/5692/5713/1445/5710/916/5719/6233/3702/3932/3120/5170/387522/3937/3123/5706/3122/920/8915/5714/5795/5688/5687/5708/5063/7189/7535/5704/7311/5694/5058/997/1147/55740/9402/5684/5720/6885/4690/3119/84433/5690/5717/9491/6500/10197/919/7316/10213/7335/7322/5715/5701/27040/23291/915/5685/917/51466/5686/7408/5728/7454/5716/5296/5693/5721 112 Human_herpesvirus_1 R-HSA-76002 Platelet activation, signaling and aggregation 220/6371 262/10654 9.061656722008575e-18 1.802121026968466e-16 6.932268152048073e-17 5295/2788/2149/5777/8526/5579/2153/5770/5291/7042/64805/2770/5175/3959/5578/5582/5908/3082/388/5583/29106/2769/5267/7423/1432/3920/374354/2244/7114/3309/2534/3690/408/2162/2768/2782/87/2776/5894/10487/2885/11343/51206/7040/9564/5874/54863/350/7043/2773/967/5879/5054/2787/5099/1072/5290/7018/6678/5340/5336/813/7094/5594/10681/7414/10490/83706/7044/7534/6810/10125/2792/6714/6694/3671/7273/22927/1191/3273/146850/27154/226/5588/5880/2335/5294/1/2785/2783/2784/1445/8525/5478/2771/94121/22915/7410/5580/2266/7409/7873/5154/3932/7076/2243/8527/801/5781/2791/2147/805/928/5170/5590/351/6464/135228/5747/51097/3937/7424/2316/3674/5552/409/2157/7277/10451/334/1277/10447/150/335/51706/308/6850/78991/8503/6403/197/4067/81/9948/998/3481/2786/54495/6654/5473/8407/7450/387/29789/10916/5595/139322/7066/151/5321/54331/5005/59345/1606/207/26090/7422/5004/51764/94235/3708/5196/3827/54518/1950/55970/2621/5216/2767/5768/346562/710/152/6647/4352/27040/2793/23533/1893/5265/7078/55664/391/5345/54676/2/1398/948/88/1675/2811/10235/5906/3479/5155/5296/5581/51368/808/213/5660/2815/9630/7057/1278/9002/2207/5627/6814/2790 220 Human_herpesvirus_1 R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 163/6371 185/10654 1.0389810371019016e-17 2.0375572560942846e-16 7.837927121996803e-17 6158/5393/6138/6227/6206/6234/6191/6128/6132/6129/23404/6176/10528/84135/27340/27043/6224/6146/6154/88745/6202/51096/6169/55272/6175/6218/5394/6173/6167/28987/116832/23481/51077/6156/117246/6143/6139/79159/23160/26168/11340/3921/10607/11103/51388/6208/6170/22984/10813/9136/6203/23246/6147/8568/6222/1454/56902/51602/6134/6155/6231/6142/23521/54555/10171/5822/6207/10969/10556/6233/6188/79707/54881/1453/4691/23016/118460/200916/6122/6230/2091/55127/6194/6166/10436/8780/9277/84128/6136/6125/6232/90459/134430/6160/92856/65083/6193/10200/6210/6229/6205/11056/9790/55131/140801/6235/55720/6181/55759/705/7311/6223/25873/51010/26354/56915/51202/9045/6187/6168/6157/6137/79050/22894/84946/6144/9349/55813/4736/57418/22803/51121/6159/25879/6217/81887/6152/57050/51065/6141/6123/55781/6164/6209/11224/6165/6130/6204/6228/10438/10199/51013/6124/25926/83732/6189/6135/6201/6161/54512/10885/6133/9188 163 Human_herpesvirus_1 R-HSA-8876198 RAB GEFs exchange GTP for GDP on RABs 88/6371 90/10654 1.1912649447640184e-17 2.3042001397353345e-16 8.863629581805819e-17 5869/163486/116442/126003/7531/22878/1122/54453/10981/5861/163259/5866/23011/9610/60684/3257/414918/51762/51552/126432/201475/5874/79961/2665/79090/22898/58485/5868/81846/51622/84079/51209/5872/9827/80006/5870/8408/9909/10000/51112/117177/83696/1121/23682/27095/6399/7109/4218/7879/2664/201627/27342/23258/5864/10260/57679/81876/259173/6305/51693/8567/208/79890/22879/54734/57589/84315/22931/51399/10890/207/122553/79958/57706/22930/55667/26130/27147/25782/9367/51560/11021/5873/5878/11031/338382/89781/160518 88 Human_herpesvirus_1 R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 82/6371 83/10654 1.3540494198053086e-17 2.5836726767095887e-16 9.938684219339108e-17 8454/5689/4893/4790/5579/5682/143471/5705/5530/5709/5695/4792/5711/5683/5699/5702/4794/3845/3265/3551/5696/5691/7314/5718/8945/4773/5966/5700/122706/5707/23198/10892/8517/10125/5970/25780/9861/5698/5692/5713/5710/2280/5478/5719/6233/801/805/4772/4775/5706/8915/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/84433/5690/5532/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5534/5716/808/5693/5721 82 Human_herpesvirus_1 R-HSA-69618 Mitotic Spindle Checkpoint 106/6371 112/10654 1.7451213792976365e-17 3.285481850091017e-16 1.2638352725860777e-16 55839/11130/11065/6249/9735/7321/5526/8697/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/996/5515/79682/10403/25936/3619/64105/332/5528/51433/79902/3796/5519/81565/91687/119504/11243/7324/83540/64682/7514/54820/6396/64946/9793/140735/220134/4928/5903/246184/55055/80776/1783/401541/79172/79980/6232/8881/5501/54821/9183/1062/699/22919/5529/51143/10393/25906/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/55166/79003/5527/701/57551 106 Human_herpesvirus_1 R-HSA-5607764 CLEC7A (Dectin-1) signaling 97/6371 101/10654 1.9079700969550493e-17 3.544807601184907e-16 1.363590817214412e-16 8454/5689/4790/5682/7321/9039/29108/143471/5705/5530/5709/5695/4792/5711/5683/5699/5702/7334/3551/5696/5691/7314/257397/5718/8945/4773/5700/122706/5707/5336/23198/23118/10892/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/801/4791/805/5170/387522/4772/4775/5706/64581/6850/8915/5714/5688/5687/5708/7189/5704/7311/5971/5694/997/1147/5684/5720/6885/84433/5690/3553/5532/5717/9491/6500/3708/10197/7316/10213/7335/10768/7322/5715/5701/23291/5685/5686/5534/5716/808/5693/5721 97 Human_herpesvirus_1 R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 92/6371 95/10654 2.1185543803840786e-17 3.7865807406358466e-16 1.4565943508037103e-16 8454/3725/9252/4790/1848/10333/4792/59307/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/11213/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/387522/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/57161 92 Human_herpesvirus_1 R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 92/6371 95/10654 2.1185543803840786e-17 3.7865807406358466e-16 1.4565943508037103e-16 8454/3725/9252/4790/1848/10333/4792/59307/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/11213/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/387522/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/57161 92 Human_herpesvirus_1 R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 92/6371 95/10654 2.1185543803840786e-17 3.7865807406358466e-16 1.4565943508037103e-16 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/2935/6134/6155/6231/6142/23521/1981/6207/6233/6188/5976/200916/6122/6230/6194/2107/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/23708/9045/6187/6168/22916/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/4686/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 92 Human_herpesvirus_1 R-HSA-2871837 FCERI mediated NF-kB activation 81/6371 82/10654 2.2488995511482e-17 3.9693077077765724e-16 1.526884432095357e-16 8454/5689/4790/5682/7321/143471/5705/5709/5695/4792/5711/5683/5699/5702/7334/3551/5696/5691/7314/257397/5718/8945/5700/122706/5707/23198/23118/10892/8517/10125/5970/9861/5588/5698/5692/5713/5710/10454/5719/6233/115727/5170/2205/387522/5706/2206/8915/5714/5688/5687/4067/5708/7189/5704/7311/5694/997/1147/5684/5720/6885/84433/5690/5717/9491/6500/10197/7316/10213/7335/7322/5715/5701/23291/5685/5686/5716/10235/5693/5721/2207 81 Human_herpesvirus_1 R-HSA-72312 rRNA processing 177/6371 205/10654 4.5546660659326166e-17 7.939738870489944e-16 3.054201026668266e-16 6158/5393/6138/6227/6206/6234/6191/6128/79922/6132/6129/23404/55226/6176/10528/84135/27340/27043/6224/6146/6154/88745/6202/51096/6169/55272/6175/6218/5394/6173/6167/28987/116832/23481/51077/6156/117246/6143/6139/79159/23160/26168/11340/3921/10607/11103/51388/6208/6170/22984/10813/60528/9136/6203/51504/23246/54433/6147/8568/27292/6222/1454/56902/51602/6134/6155/6231/6142/23521/54555/10171/5822/6207/10969/10556/6233/6188/79707/54881/1453/4691/23016/118460/200916/6122/6230/2091/55651/55127/6194/6166/3028/10436/8780/9277/84128/6136/6125/4839/6232/90459/134430/6160/92856/65083/6193/10200/6210/6229/6205/115939/11056/9790/55131/140801/6235/55720/6181/55759/705/7311/6223/25873/55505/51010/26354/56915/51202/9045/51106/6187/6168/6157/6137/79050/22894/84946/6144/9349/55813/4736/57418/22803/51121/6159/25879/6217/81887/6152/57050/51065/6141/6123/55781/6164/54931/6209/11224/6165/6130/6204/1736/6228/10438/10199/51013/6124/25926/83732/6189/6135/6201/6161/54512/10885/6133/9188 177 Human_herpesvirus_1 R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic 95/6371 99/10654 4.982383612937226e-17 8.579421538374833e-16 3.3002695048467374e-16 11014/64837/11127/51807/53407/347688/3798/5861/10381/285643/55738/10112/64147/7846/51226/81027/11004/10749/81930/54732/60561/113220/3797/29127/55605/377/1315/3796/124602/11316/55614/89953/56992/8729/23423/10376/1314/3835/147700/3833/378/9493/26286/26958/10959/3831/84364/22820/84617/55850/9585/10382/3832/7277/9554/23303/8775/26153/81876/9183/1062/11015/146909/347733/662/90990/23046/10383/24137/84790/84643/10945/51594/22920/7280/55582/9371/51014/23095/63908/112714/6836/547/8774/10972/381/4905/3834/9276/55083/3799/375/221458/22818/372 95 Human_herpesvirus_1 R-HSA-156842 Eukaryotic Translation Elongation 90/6371 93/10654 5.621635313687052e-17 9.56355308786279e-16 3.6788380746512597e-16 6158/6138/6227/6206/6234/6191/6128/6132/1917/6129/1915/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6166/1938/6136/6125/1937/6232/6160/1933/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/1936/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 90 Human_herpesvirus_1 R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 119/6371 129/10654 5.8498946067574e-17 9.833394267549343e-16 3.782638617903281e-16 8454/3725/9252/4790/7321/1848/1785/10333/4792/59307/177/1432/929/3654/51135/6196/1759/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/1326/5601/5606/11213/8737/8767/5336/1849/29110/5594/4214/23118/841/8517/5528/7323/5970/7096/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/671/1846/3665/351/387522/653509/3684/330/51295/79155/8651/26052/7867/64127/5602/3656/57162/695/7189/7311/9641/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/7322/329/466/23291/114609/6288/2002/6285/5609/948/1385/5599/353376/7097/3929/57161/3689/148022 119 Human_herpesvirus_1 R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 79/6371 80/10654 6.199673376947057e-17 1.029875153911676e-15 3.961648869974838e-16 8454/5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 79 Human_herpesvirus_1 R-HSA-168898 Toll-like Receptor Cascades 139/6371 155/10654 7.966231050122993e-17 1.3079439817178683e-15 5.031303821130312e-16 8454/3725/10695/9252/4790/7321/1848/1785/6280/10333/4792/59307/177/1432/2244/929/3654/51135/6196/1759/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/54106/11035/8945/1326/5601/5606/11213/8737/8767/5336/1849/29110/5594/4214/23118/841/8517/5528/7323/5970/7096/9261/5519/5598/4208/6195/10454/3661/6233/51311/10010/2266/2353/2243/8772/5600/5781/30849/5608/4791/671/1508/1846/3665/351/81793/387522/7184/653509/3684/8411/330/51295/7098/338/79155/6279/8651/26052/7867/64127/5602/3656/57162/695/7189/81622/7311/9641/6416/51284/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7100/7316/7335/4205/5289/4793/5641/3146/7322/329/466/23291/114609/6288/2002/6285/5609/948/1385/5599/353376/7097/3929/57161/3689/148022 139 Human_herpesvirus_1 R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 78/6371 79/10654 1.0290321347184965e-16 1.6701073266925483e-15 6.424447447244334e-16 2074/5982/7507/5431/5435/9978/5433/10980/57654/2965/5439/10987/2067/2967/6117/10714/91603/7314/6118/404672/3150/5438/3978/5985/10920/2068/5984/6233/7874/5424/8451/10450/5434/5436/7515/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/2071/51426/2873/7311/3980/8533/5983/5432/51138/56655/9318/6917/5440/902/27339/5430/57804/5441/2072/7316/64708/5426/5437/2033/2968/56949/9716/2073/5981/57461/1022/8178/50813 78 Human_herpesvirus_1 R-HSA-68886 M Phase 312/6371 395/10654 1.1956016359977052e-16 1.9183971704872272e-15 7.379550767641338e-16 114791/10844/23165/5689/55839/11130/11065/440145/6249/5579/5682/9735/7531/1459/11190/7321/91754/203068/5526/54801/51807/8697/5578/9212/347688/10274/5861/5925/1460/147841/348995/79441/143471/10381/57122/5705/5116/1780/23122/23511/5048/5709/5695/57405/8655/1457/23279/9702/5711/2491/10112/7846/23225/7840/5683/1060/5699/9663/11064/5702/5520/81027/51529/4001/29945/11004/23133/51434/9184/9972/5518/55844/55835/29922/8021/29882/23332/84930/25909/10726/81930/55746/93323/5696/5691/7314/996/5515/5718/79682/10403/64151/25936/55869/5700/122706/5707/1454/2801/5594/3619/23198/64105/23310/332/10762/10051/5528/983/8548/51433/9861/79902/3796/8615/79959/5519/9883/81565/221496/2029/7444/5698/5692/5713/80097/91687/119504/11243/10376/23397/5710/10540/85378/7324/83540/2010/64900/5719/64682/6233/23175/7514/54930/54820/113130/9493/6396/129401/1453/27229/64946/9793/140735/220134/84617/4928/26271/5903/55706/7175/11258/22981/246184/55055/8636/80776/1783/401541/7532/55125/10382/79172/121441/7277/5706/9133/79980/25836/6232/23047/8881/9814/653784/5885/23354/891/5501/9738/1639/5714/55722/4957/4927/5566/54821/81876/9183/5688/1062/699/5687/7283/5708/347733/22919/8243/10426/5529/22994/51143/1069/8086/10393/79648/5577/5704/7311/25906/10383/5347/54892/84790/84643/80184/5694/22897/6418/5108/7112/10592/7280/10806/29781/5595/1778/5516/4000/115106/4926/5905/22995/55559/81929/5684/5720/54908/55143/9631/5525/10142/1058/991/79019/5862/348235/80152/5690/1063/8379/95681/5717/9491/23244/23421/55920/79023/23636/10735/10197/7443/112714/1781/7316/10213/80321/10776/53371/26003/4085/9688/55166/10121/5715/84131/5701/5685/3320/8815/5686/79003/9126/9918/10733/4751/9232/23592/9700/5527/27175/80254/5716/701/57551/9662/55142/64689/8481/5693/5721/55755/8480 312 Human_herpesvirus_1 R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 83/6371 85/10654 1.4283157819546496e-16 2.2660470608089496e-15 8.716865091526899e-16 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/91768/5934/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/1163/1019/5706/286826/4331/5714/5688/5687/91750/5708/1874/208/5704/55957/51343/7311/5694/1017/5684/994/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5715/5701/5685/5686/5716/1022/5693/5721/132660 83 Human_herpesvirus_1 R-HSA-2500257 Resolution of Sister Chromatid Cohesion 116/6371 126/10654 2.1934358077856854e-16 3.4412570673259863e-15 1.323757750663642e-15 55839/11130/6249/9735/5526/51807/9212/347688/10274/147841/348995/10381/57122/1780/23122/5048/57405/8655/23279/2491/7846/1060/81027/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/55869/3619/64105/332/5528/983/79902/3796/5519/81565/91687/11243/10376/83540/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/55055/80776/1783/401541/10382/79172/7277/9133/79980/6232/23047/5885/891/5501/54821/9183/1062/699/347733/22919/8243/5529/51143/10383/5347/84790/84643/7280/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23244/23421/55920/79023/10735/112714/1781/4085/55166/79003/9126/5527/701/57551 116 Human_herpesvirus_1 R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 82/6371 84/10654 2.345103211161144e-16 3.638775532043446e-15 1.399737717708676e-15 10445/5982/6613/7507/9978/85015/10980/2965/10987/2067/2967/6612/6117/7334/10714/7314/6118/83444/404672/9557/86/3978/1643/29844/5985/10920/2068/5984/6233/93973/8607/5424/5886/8451/8554/7515/54107/8450/4331/5425/5111/2966/6119/5427/1642/142/125476/2071/1069/7329/51426/2873/7311/3980/60/8533/5983/10038/51138/7528/56655/9318/902/57804/7336/2072/54778/7316/64708/5426/283899/7341/79913/10401/54617/2968/5887/2073/5981/1022/50813/7508 82 Human_herpesvirus_1 R-HSA-162587 HIV Life Cycle 136/6371 152/10654 2.7517069368462425e-16 4.223271950898798e-15 1.6245775508154018e-15 6884/23165/6875/2237/7852/27243/6874/348995/57122/3981/5431/23511/5435/5433/2960/51271/23279/23327/29082/8732/23225/2965/27183/5439/6873/3836/9972/6881/2967/51616/8021/11198/904/51497/55746/92421/7314/137492/25978/51160/2959/7518/404672/10015/91782/5438/3978/10762/79720/4836/9397/79902/11168/9883/89853/83860/2068/5902/5478/6233/7514/1025/6396/129401/6883/7936/6829/2957/25920/4928/2963/5434/5903/55706/7175/79643/5436/6878/920/4331/4927/8148/2966/2962/54457/8812/128866/905/2071/5901/8086/7311/93343/6880/6908/7251/1104/2547/6882/2961/5432/22916/1234/6877/5905/6917/81929/5440/902/9631/3159/5430/7520/6749/79023/5441/23636/7469/4686/7316/6872/53371/9688/8731/6879/9150/9525/2958/5437/8815/6827/2968/138474/1022/8178/8480 136 Human_herpesvirus_1 R-HSA-69202 Cyclin E associated events during G1/S transition 81/6371 83/10654 3.8490329870533583e-16 5.843908148085314e-15 2.2479921010973774e-15 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/91768/5934/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/1163/1019/5706/286826/4331/5714/5688/5687/91750/5708/1874/208/5704/55957/7311/5694/1017/5684/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5715/5701/5685/5686/5716/1022/5693/5721/132660 81 Human_herpesvirus_1 R-HSA-156902 Peptide chain elongation 86/6371 89/10654 3.938776856130282e-16 5.916545660485062e-15 2.2759337712914063e-15 6158/6138/6227/6206/6234/6191/6128/6132/6129/1915/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6166/1938/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 86 Human_herpesvirus_1 R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 75/6371 76/10654 4.69929369654372e-16 6.984634420547087e-15 2.6867983904892627e-15 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 75 Human_herpesvirus_1 R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 90/6371 94/10654 5.444430135521189e-16 8.007849324329082e-15 3.0804012608869888e-15 8454/3725/9252/4790/7321/1848/4792/177/1432/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/1326/5601/5606/8737/8767/1849/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5608/4791/1846/3665/351/387522/330/7098/79155/7867/64127/5602/3656/7189/7311/9641/6416/5595/5516/1147/1845/6885/5604/10392/6500/7316/7335/4205/4793/3146/7322/329/466/23291/6288/2002/6285/5609/1385/5599/148022 90 Human_herpesvirus_1 R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 80/6371 82/10654 6.315247630151244e-16 9.099111891605669e-15 3.500180211770185e-15 114791/10844/440145/7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/1454/983/79959/80097/10540/85378/54930/54820/1453/27229/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/728642/9738/1639/55722/4957/5566/7283/22919/984/10426/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 80 Human_herpesvirus_1 R-HSA-380287 Centrosome maturation 80/6371 82/10654 6.315247630151244e-16 9.099111891605669e-15 3.500180211770185e-15 114791/10844/440145/7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/1454/983/79959/80097/10540/85378/54930/54820/1453/27229/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/728642/9738/1639/55722/4957/5566/7283/22919/984/10426/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 80 Human_herpesvirus_1 R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 85/6371 88/10654 6.401313679484609e-16 9.129954460032594e-15 3.512044506766676e-15 8454/7531/11190/203068/54801/79441/5116/5048/8655/6790/9702/7846/7840/11064/5518/55835/23332/93323/7314/8945/4659/1454/983/79959/10540/6233/54930/54820/1453/9793/4218/5500/11258/22981/8636/7532/84962/55125/10382/121441/7277/9133/9814/23354/891/9738/1639/55722/4957/5566/7283/22919/22994/79866/1069/5577/7311/10133/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/6500/1781/7316/80321/10121/84131/23291/3320/10733/4751/80254/9662/55142/8481/55755 85 Human_herpesvirus_1 R-HSA-166166 MyD88-independent TLR4 cascade 94/6371 99/10654 6.563630739340153e-16 9.176085746483461e-15 3.529789954663387e-15 8454/3725/9252/4790/7321/1848/4792/177/1432/929/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/1326/5601/5606/8737/8767/1849/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/1846/3665/351/387522/330/79155/7867/64127/5602/3656/7189/7311/9641/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/7316/7335/4205/4793/3146/7322/329/466/23291/6288/2002/6285/5609/1385/5599/353376/148022 94 Human_herpesvirus_1 R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 94/6371 99/10654 6.563630739340153e-16 9.176085746483461e-15 3.529789954663387e-15 8454/3725/9252/4790/7321/1848/4792/177/1432/929/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/1326/5601/5606/8737/8767/1849/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/1846/3665/351/387522/330/79155/7867/64127/5602/3656/7189/7311/9641/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/7316/7335/4205/4793/3146/7322/329/466/23291/6288/2002/6285/5609/1385/5599/353376/148022 94 Human_herpesvirus_1 R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 74/6371 75/10654 7.792958658101307e-16 1.07878996325873e-14 4.149810802456423e-15 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 74 Human_herpesvirus_1 R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 89/6371 93/10654 8.769998234720239e-16 1.1793559530880931e-14 4.536660740968064e-15 8454/3725/9252/4790/1848/4792/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/1846/3665/351/387522/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/353376/57161/148022 89 Human_herpesvirus_1 R-HSA-72764 Eukaryotic Translation Termination 89/6371 93/10654 8.769998234720239e-16 1.1793559530880931e-14 4.536660740968064e-15 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/51504/6147/6222/2935/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/2107/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/23708/9045/6187/6168/6157/6137/6144/9349/4736/327/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 89 Human_herpesvirus_1 R-HSA-975155 MyD88 dependent cascade initiated on endosome 89/6371 93/10654 8.769998234720239e-16 1.1793559530880931e-14 4.536660740968064e-15 8454/3725/9252/4790/1848/4792/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/1846/3665/351/387522/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/353376/57161/148022 89 Human_herpesvirus_1 R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 93/6371 98/10654 1.0488010516353079e-15 1.3712102638046803e-14 5.274671955592777e-15 8454/3725/9252/4790/1848/10333/4792/59307/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/11213/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/387522/653509/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/57161 93 Human_herpesvirus_1 R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 93/6371 98/10654 1.0488010516353079e-15 1.3712102638046803e-14 5.274671955592777e-15 8454/3725/9252/4790/1848/10333/4792/59307/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/11213/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/387522/653509/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/57161 93 Human_herpesvirus_1 R-HSA-202424 Downstream TCR signaling 93/6371 98/10654 1.0488010516353079e-15 1.3712102638046803e-14 5.274671955592777e-15 5295/8454/5689/4790/5682/5291/7321/143471/5705/3115/5709/5695/4792/3113/5711/3117/5683/5699/5702/3127/7334/3551/5696/5691/7314/5718/8945/3635/5290/5700/122706/5707/8767/23198/23118/10892/8517/5970/9861/5588/5698/5692/5713/5710/916/5719/6233/3932/3120/5170/387522/3123/5706/3122/920/8915/5714/5688/5687/5708/7189/5704/7311/5694/997/1147/5684/5720/6885/3119/84433/5690/5717/9491/6500/10197/919/7316/10213/7335/7322/5715/5701/23291/915/5685/917/5686/5728/5716/5296/5693/5721 93 Human_herpesvirus_1 R-HSA-877300 Interferon gamma signaling 88/6371 92/10654 1.4119469838265739e-15 1.8124264919664748e-14 6.9719104655934175e-15 80263/5777/960/5770/3107/817/9021/3383/55223/3662/3115/4684/567/6672/3113/3106/3459/3717/3117/11074/5371/3133/117854/3127/4938/4261/818/115362/7412/85363/9830/163351/2634/115361/10475/10437/10612/3458/3661/5580/81603/10107/4940/5781/3660/8554/3135/3665/3120/10379/2633/3123/23650/2209/8638/7706/23087/3122/3394/3663/6772/8651/3659/2635/5771/816/10346/3716/7726/79097/53840/3105/3460/815/6737/23321/4281/3119/4502/51127/3664/4939/388646/7341/55128/3134/80128/5724 88 Human_herpesvirus_1 R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 88/6371 92/10654 1.4119469838265739e-15 1.8124264919664748e-14 6.9719104655934175e-15 8454/3725/9252/4790/1848/4792/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/1846/351/387522/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/353376/57161/148022 88 Human_herpesvirus_1 R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 92/6371 97/10654 1.6748910994675247e-15 2.130582191394725e-14 8.195768680182483e-15 8454/3725/9252/4790/1848/4792/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/30849/5608/4791/1846/3665/351/387522/8411/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/5289/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/353376/57161/148022 92 Human_herpesvirus_1 R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 78/6371 80/10654 1.6982559218647022e-15 2.141015501493714e-14 8.235902778967918e-15 3839/23165/201626/5335/348995/317649/57122/11274/23511/4734/23279/8672/23225/1973/3836/4599/9972/8021/7334/4938/55746/7314/402569/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/1977/51191/6233/5610/4940/6396/129401/4928/3838/5903/55706/7175/2316/4600/3841/8638/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/7318/1974/5595/3837/81929/9631/79023/23636/7316/53371/9688/6041/4939/6059/5300/9775/5495/8480 78 Human_herpesvirus_1 R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72/6371 73/10654 2.141576101893854e-15 2.676022527322232e-14 1.0293928910826538e-14 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/5716/701/5693/5721 72 Human_herpesvirus_1 R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic 172/6371 202/10654 2.358813362764224e-15 2.9216179545816534e-14 1.123866754558024e-14 6811/400/11014/64837/11311/8674/11127/51807/53407/347688/3798/5861/10381/1780/5048/9570/8655/84516/832/285643/55738/10112/636/64147/7846/2590/3482/51226/9382/81027/11004/10228/10749/6293/8675/81930/10652/54732/7110/51164/60561/113220/3797/10618/9321/29127/55275/55605/23299/51209/377/10466/23647/9827/1315/22836/3796/5870/79571/124602/11316/55614/89953/56992/91949/8729/4074/23423/10376/1314/10540/250/3835/147700/3833/8677/378/9493/26286/26958/140735/10959/1523/3831/84364/22820/51542/84617/11258/1783/27333/55850/9585/10382/93661/55860/830/3832/7277/10671/9554/23303/1639/8775/26153/81876/9183/9712/1062/11015/146909/347733/662/90990/10244/51143/9648/23046/10383/24137/84790/54734/84643/10945/5049/57589/51594/22920/7280/829/22931/1778/55582/5321/9371/25839/51014/23095/5050/84316/83548/9950/63908/112714/1781/22930/738/25782/10121/9367/10226/9341/9342/9527/6836/57511/547/51560/8774/143187/10972/381/4905/3834/9276/55083/3799/9266/375/221458/22818/372 172 Human_herpesvirus_1 R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 82/6371 85/10654 2.7403959609471534e-15 3.3072129032969066e-14 1.2721946161482063e-14 8454/3725/9252/4790/1848/4792/177/1432/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/81793/387522/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/246330/4615/7100/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 82 Human_herpesvirus_1 R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 82/6371 85/10654 2.7403959609471534e-15 3.3072129032969066e-14 1.2721946161482063e-14 8454/3725/9252/4790/1848/4792/177/1432/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/81793/387522/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/246330/4615/7100/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 82 Human_herpesvirus_1 R-HSA-975871 MyD88 cascade initiated on plasma membrane 82/6371 85/10654 2.7403959609471534e-15 3.3072129032969066e-14 1.2721946161482063e-14 8454/3725/9252/4790/1848/4792/177/1432/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/81793/387522/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/246330/4615/7100/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 82 Human_herpesvirus_1 R-HSA-2262752 Cellular responses to stress 366/6371 479/10654 3.382555246575055e-15 4.047600006918625e-14 1.557001344543023e-14 1912/23165/5689/3725/9134/2077/11065/573/4790/54468/5682/64344/7531/1915/11133/7321/51807/817/6045/8697/9530/347688/23677/27327/80012/7295/5925/3091/348995/143471/472/10381/57122/5705/79813/3576/3313/1780/7001/23511/10312/5709/9978/2114/1869/5695/3305/8655/84516/1911/832/26277/23279/4194/1031/5711/5928/1432/1387/4683/10325/7846/23225/5683/3309/23512/57332/5699/126374/7428/5702/192669/9531/81027/8900/51529/4001/29945/8091/8131/2056/51434/2475/1032/3306/1030/6196/9972/10670/23411/8021/4343/6117/10587/6197/29882/3312/4217/54386/3569/64121/55746/5696/5691/7296/7314/51164/996/51182/5718/818/3303/7014/6118/51606/5601/2876/5606/7027/526/5700/122706/5707/2146/9550/2936/9114/5594/3308/84335/23198/898/10049/10013/27244/3337/10762/847/7323/890/5970/9261/6667/51433/9861/79902/5598/9883/2932/84733/529/5698/5692/5713/2877/119504/10376/6195/5710/3301/10540/7157/7324/5719/64682/6233/2353/538/8726/6396/1535/129401/5600/523/201163/26523/528/405/5608/3297/57521/140735/768/6015/28956/84617/4928/4688/1019/5903/83667/55706/7175/653361/5241/11258/9448/246184/112399/1029/1783/389541/8535/84962/10382/93661/5931/58528/10294/55860/830/7013/7277/1051/1410/50488/5706/10671/8881/527/6774/1639/5714/4927/7867/64223/6119/26353/3552/10370/10524/5688/57805/5687/3310/2908/5708/347733/5602/7266/25824/6009/51143/816/6648/8086/10393/1870/5704/3326/55004/51343/7311/367/25906/3397/2034/57634/10383/84790/55662/648/5694/3304/23466/3456/2113/6416/10641/257202/7280/10728/829/2880/23523/5595/1778/1017/815/25913/81929/5684/5720/9631/3159/7290/23334/10111/2878/7422/5690/57690/5717/1027/9491/545/79023/23636/10197/192670/10808/153129/112714/3490/8550/29855/4306/1781/7316/10213/10935/53371/1026/9532/54205/2289/9588/9688/10121/7415/1871/6647/8994/7322/5715/2882/5701/112398/245972/144577/5685/8649/3320/65057/5686/2033/1021/6767/25842/493869/8453/23135/10963/22824/23112/5609/10542/4689/5716/9529/5599/54583/5052/1536/5693/5721/55466/2288/5034/8480/10919/51382/4193/2950/9296/23043 366 Human_herpesvirus_1 R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 71/6371 72/10654 3.548876131292087e-15 4.1413331383342366e-14 1.5930579240945776e-14 5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 71 Human_herpesvirus_1 R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 71/6371 72/10654 3.548876131292087e-15 4.1413331383342366e-14 1.5930579240945776e-14 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 71 Human_herpesvirus_1 R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 71/6371 72/10654 3.548876131292087e-15 4.1413331383342366e-14 1.5930579240945776e-14 5689/9134/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/990/5699/5702/8900/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/898/890/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/1017/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 71 Human_herpesvirus_1 R-HSA-450294 MAP kinase activation 64/6371 64/10654 4.497105491497019e-15 5.204846683601468e-14 2.0021625829270596e-14 8454/3725/9252/4790/1848/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/23118/8517/5528/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/1846/387522/79155/7867/64127/5602/3656/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/7316/7335/4205/466/23291/2002/5609/1385/5599 64 Human_herpesvirus_1 R-HSA-192823 Viral mRNA Translation 85/6371 89/10654 5.873022117576546e-15 6.588764817276829e-14 2.5345181494817683e-14 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/5611/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 85 Human_herpesvirus_1 R-HSA-5687128 MAPK6/MAPK4 signaling 85/6371 89/10654 5.873022117576546e-15 6.588764817276829e-14 2.5345181494817683e-14 2308/5689/2118/3725/5682/27327/143471/5705/5709/5695/4609/5711/5683/5699/5702/192669/8997/4343/5062/5696/5691/7314/5879/5718/5700/122706/5707/5567/23198/3337/983/9861/5698/5692/10435/5713/5710/8555/896/5719/6233/7514/26523/10602/5568/3315/5706/5597/5714/5566/5688/5687/5708/5063/998/5704/7311/5694/5058/27161/5684/5720/2309/10642/5690/57690/5717/9491/10197/192670/5596/8550/7316/10213/5715/5701/5685/5686/8556/23112/5716/5896/8202/5693/5721 85 Human_herpesvirus_1 R-HSA-6802957 Oncogenic MAPK signaling 70/6371 71/10654 5.879492683972242e-15 6.588764817276829e-14 2.5345181494817683e-14 4893/71/817/5908/55109/54845/8546/22866/5605/5037/3717/10827/2244/3690/408/4296/5894/8826/1185/4140/3845/3265/4763/818/8805/55750/8844/7094/5594/7414/10533/23164/57085/6714/9061/2335/1445/2266/2243/369/801/57670/805/283455/3674/409/673/8315/816/56829/7450/60/9444/7529/5595/4000/27044/815/22906/8087/5604/10018/10142/54518/80853/10256/5906/808/9715/5245 70 Human_herpesvirus_1 R-HSA-68949 Orc1 removal from chromatin 70/6371 71/10654 5.879492683972242e-15 6.588764817276829e-14 2.5345181494817683e-14 8454/5689/5682/143471/5705/5709/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/890/9861/6502/5698/5692/5713/4175/5710/5719/6233/4999/4172/5000/4173/5706/5714/5688/5687/5708/81620/5704/23595/7311/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 70 Human_herpesvirus_1 R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 89/6371 94/10654 6.7965110400463506e-15 7.556435896492478e-14 2.906754825249828e-14 114791/10844/440145/7531/11190/203068/54801/51807/347688/79441/10381/5116/5048/8655/9702/7846/7840/11064/81027/5518/55835/29922/23332/93323/1454/983/79959/80097/10376/10540/85378/54930/54820/1453/27229/9793/84617/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/9738/1639/55722/4957/5566/7283/347733/22919/10426/22994/1069/5577/10383/5347/84790/80184/22897/5108/7280/10806/1778/115106/4926/22995/55559/10142/95681/112714/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 89 Human_herpesvirus_1 R-HSA-1236974 ER-Phagosome pathway 80/6371 83/10654 7.208097144609613e-15 7.951432162647479e-14 3.0586991172850006e-14 8773/5689/5682/3107/811/143471/5705/10333/5709/5695/567/3106/5711/5683/929/5699/5702/3133/3551/5696/5691/7314/5718/10952/5700/122706/5707/23198/6892/8517/6810/7096/9861/5698/5692/5713/5710/5719/6233/3135/6890/5706/9554/29927/5714/5688/5687/5708/2923/695/5704/7311/5694/8673/3105/23643/1147/5684/5720/5690/5717/9491/10197/7099/4615/6891/7316/10213/5715/5701/9341/5685/5686/114609/948/5716/3134/7097/5693/5721 80 Human_herpesvirus_1 R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 96/6371 103/10654 1.0897266096790196e-14 1.1927860254781206e-13 4.588322567069556e-14 5295/374/3643/2250/5291/5526/7039/3082/941/2064/145957/2534/9965/2264/3630/3654/9542/2885/51135/8660/5518/2252/2253/5879/5515/1839/5290/3667/8823/90865/2065/3815/5594/2069/8074/2260/5528/2249/6714/2099/2248/5519/2247/5880/7409/2246/2251/5154/3932/118788/8394/255324/5781/940/930/2263/4233/8503/5159/29851/3084/5529/7189/9365/10718/5293/1956/2549/5595/3556/5516/8822/685/5305/5525/8870/207/8817/4615/2100/2254/152831/1950/26281/10818/2261/2255/391/2066/27006/942/5527/5155/4254/5296/5156 96 Human_herpesvirus_1 R-HSA-5621481 C-type lectin receptors (CLRs) 126/6371 142/10654 1.6237411379889248e-14 1.763632682184894e-13 6.784213985443606e-14 8454/5689/4586/9252/4893/4790/5682/7321/9039/29108/143471/5705/5530/5709/5695/4792/5711/1387/5683/2534/5699/5702/5894/3845/7334/3265/3551/5062/5696/50856/5691/7314/257397/5718/8945/4773/4589/5700/122706/5707/5567/5336/4582/23198/23118/10892/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/801/4791/805/5170/387522/4772/338339/5568/4775/5706/64581/6850/8915/5714/5566/170482/5688/5687/4067/5708/5063/7189/5704/30835/7311/5971/4585/5694/5058/997/1147/5684/5720/6885/84433/5690/3553/5532/5717/9491/6500/3708/10197/118430/7316/10213/94025/7335/10768/7322/5715/93978/5701/23291/5685/5686/2033/5534/200958/5716/808/5693/5721/2207/26253 126 Human_herpesvirus_1 R-HSA-199977 ER to Golgi Anterograde Transport 135/6371 154/10654 1.7828393390095426e-14 1.9216558371614305e-13 7.392085969698064e-14 6811/23256/374/6711/11014/126003/2153/51807/286/10484/7039/347688/5861/10381/1780/9570/8655/84516/832/3998/55738/7846/51226/9382/375056/9632/3630/81027/6709/79090/10652/54732/51164/58485/10342/4253/2801/377/10466/22872/1315/8615/55014/11316/91949/8729/23423/10376/1314/10540/51332/83696/27095/6399/7109/378/6396/26286/1453/26958/140735/10959/84364/22820/84617/11258/6712/2890/1783/10382/10802/93661/55860/2157/830/7277/10671/9554/966/11196/1639/149111/10282/6710/8775/81876/11015/347733/51143/51693/23243/5537/9871/10383/84790/10945/1075/7280/829/1778/9919/10113/51399/11070/25839/55291/51014/122553/26984/83548/63908/112714/1604/1781/57731/1522/10121/2804/9527/57511/22870/5265/8774/10972/381/6708/4905/9276/287/375/64689/288/10427/22818/372 135 Human_herpesvirus_1 R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 73/6371 75/10654 2.0006536581081143e-14 2.140093155491407e-13 8.232354765420949e-14 5295/374/2250/5291/7039/3082/941/2064/145957/2534/9965/2264/9542/2885/8660/2252/2253/5879/1839/5290/3667/8823/2065/3815/2069/8074/2260/2249/6714/2099/2248/2247/5880/7409/2246/2251/5154/3932/118788/255324/5781/940/930/2263/4233/8503/5159/29851/3084/9365/10718/5293/1956/2549/8822/685/8817/2100/2254/152831/1950/26281/10818/2261/2255/391/2066/27006/942/5155/4254/5296/5156 73 Human_herpesvirus_1 R-HSA-9007101 Rab regulation of trafficking 112/6371 124/10654 2.4775617144000358e-14 2.63031363964876e-13 1.0118099284767854e-13 5869/163486/116442/126003/7531/22878/1122/54453/57533/10981/83874/5861/163259/5866/23011/9610/60684/3257/414918/51762/51552/9230/126432/201475/5874/79961/2665/79090/22898/58485/4943/5868/81846/51622/7249/23637/84079/51209/5872/9827/80006/5870/8408/9909/10000/64786/51112/117177/83696/1121/23682/27095/6399/7109/4218/7879/2664/201627/26088/27342/414060/23258/9363/5864/10260/382/57679/81876/9135/259173/6305/51693/8567/208/5867/79890/22879/10133/11345/54734/57589/84315/7248/22931/51399/10890/23062/207/11337/51256/122553/79958/57706/8766/22930/55667/26130/27147/25782/9367/51560/11021/5873/79735/81631/5878/11031/23163/338382/57465/89781/160518 112 Human_herpesvirus_1 R-HSA-5658442 Regulation of RAS by GAPs 67/6371 68/10654 2.6694036186345982e-14 2.7919984514904093e-13 1.0740056664447976e-13 5689/4893/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/3845/3265/4763/5696/5691/7314/5718/10156/8831/5700/122706/5707/23198/5921/9861/5698/5692/5713/5710/5719/6233/200734/22821/9462/5706/84078/5714/64926/5688/5687/5708/5704/7311/5694/5684/5720/153090/5690/5717/9491/10197/7316/10213/5715/8437/5701/5922/5685/5686/5716/399473/5693/5721/161742 67 Human_herpesvirus_1 R-HSA-68867 Assembly of the pre-replicative complex 67/6371 68/10654 2.6694036186345982e-14 2.7919984514904093e-13 1.0740056664447976e-13 5689/5682/143471/5705/5709/1869/4174/5695/84515/4998/5711/5683/990/5699/5702/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/9861/5698/5692/5713/4175/5710/5719/6233/4999/4172/5000/4173/5706/5714/51053/5688/5687/5708/81620/1870/5704/23595/7311/5694/4176/5684/5720/5690/5717/9491/10197/7316/10213/4171/1871/5715/5701/5685/5686/5716/5693/5721 67 Human_herpesvirus_1 R-HSA-141424 Amplification of signal from the kinetochores 90/6371 96/10654 2.8122483210166646e-14 2.898463233047832e-13 1.1149597646135991e-13 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/79902/3796/5519/81565/91687/11243/83540/7514/54820/6396/64946/9793/140735/220134/4928/5903/55055/80776/1783/401541/79172/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/55166/79003/5527/701/57551 90 Human_herpesvirus_1 R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 90/6371 96/10654 2.8122483210166646e-14 2.898463233047832e-13 1.1149597646135991e-13 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/79902/3796/5519/81565/91687/11243/83540/7514/54820/6396/64946/9793/140735/220134/4928/5903/55055/80776/1783/401541/79172/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/55166/79003/5527/701/57551 90 Human_herpesvirus_1 R-HSA-199418 Negative regulation of the PI3K/AKT network 101/6371 110/10654 3.204154484564261e-14 3.2784537189889394e-13 1.2611317422083592e-13 5295/374/3643/2250/5291/5526/7039/3082/941/2064/145957/2534/9965/2264/3630/3654/9542/2885/51135/8660/5518/2252/2253/5879/5515/1839/5290/3667/8823/90865/2065/3815/5594/2069/8074/57761/2260/5528/2249/6714/2099/2248/5519/2247/5880/10000/7409/2246/2251/5154/3932/118788/8394/255324/5781/940/23239/930/2263/4233/8503/5159/29851/3084/5529/7189/208/9365/10718/5293/1956/2549/5595/3556/5516/8822/685/5305/5525/8870/207/8817/4615/2100/2254/152831/1950/26281/10818/2261/2255/391/5728/2066/27006/942/5527/5155/4254/5296/5156 101 Human_herpesvirus_1 R-HSA-5663220 RHO GTPases Activate Formins 124/6371 140/10654 3.631239512864748e-14 3.688712368464046e-13 1.4189470569013328e-13 55839/11130/71/6249/9735/5526/51807/9212/347688/388/147841/348995/10381/57122/1780/23122/3688/5048/57405/8655/23279/2491/7846/1060/81027/11004/1855/9184/5518/23332/25909/10726/81930/55746/5879/5515/79682/10403/25936/1856/389/3619/64105/332/5528/6714/79902/3796/5519/81565/91687/11243/10376/83540/1857/7514/54820/29984/1729/6396/64946/9793/140735/220134/84617/4928/5903/55055/80776/1783/401541/10382/79172/7277/79980/6232/5501/54821/9183/1062/699/752/347733/22919/5529/51143/998/10383/5347/387/60/84790/84643/7280/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/6722/8379/23421/55920/79023/112714/1781/4085/5216/81624/55166/51466/79003/5527/701/23380/57551 124 Human_herpesvirus_1 R-HSA-1169091 Activation of NF-kappaB in B cells 66/6371 67/10654 4.4178070838172166e-14 4.362198323321615e-13 1.678018737762005e-13 8454/5689/4790/5579/5682/143471/5705/5709/5695/4792/5711/5683/5699/5702/4794/3551/5696/5691/7314/5718/8945/5966/5700/122706/5707/23198/10892/8517/5970/9861/5698/5692/5713/5710/5719/6233/5706/8915/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/84433/5690/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5716/5693/5721 66 Human_herpesvirus_1 R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 66/6371 67/10654 4.4178070838172166e-14 4.362198323321615e-13 1.678018737762005e-13 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 66 Human_herpesvirus_1 R-HSA-6802952 Signaling by BRAF and RAF fusions 66/6371 67/10654 4.4178070838172166e-14 4.362198323321615e-13 1.678018737762005e-13 4893/71/817/5908/55109/54845/8546/22866/5605/5037/3717/10827/2244/3690/408/5894/8826/1185/4140/3845/3265/818/8805/55750/8844/7094/5594/7414/10533/23164/57085/6714/9061/2335/1445/2266/2243/369/801/57670/805/283455/3674/409/673/816/56829/7450/60/9444/7529/5595/4000/27044/815/22906/8087/5604/10018/10142/54518/80853/10256/5906/808/9715 66 Human_herpesvirus_1 R-HSA-73856 RNA Polymerase II Transcription Termination 66/6371 67/10654 4.4178070838172166e-14 4.362198323321615e-13 1.678018737762005e-13 8683/6431/84271/51585/199746/81608/1477/65109/9877/7919/53981/6432/8563/6430/134353/11051/80145/8106/22794/9785/11338/4116/1478/51213/10250/26097/51362/23283/6636/10914/57187/79228/84324/6635/7884/6428/10212/84967/6637/55110/84321/6429/10898/10569/9295/51692/9939/6426/22916/1479/10921/25888/79869/29894/4686/8189/10978/7307/9984/10189/6634/9775/84248/6427/55339/6628 66 Human_herpesvirus_1 R-HSA-8854518 AURKA Activation by TPX2 71/6371 73/10654 5.350802717492881e-14 5.246759331319408e-13 2.0182852355455604e-13 7531/11190/203068/54801/79441/5116/5048/8655/6790/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/22974/3161/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 71 Human_herpesvirus_1 R-HSA-162599 Late Phase of HIV Life Cycle 123/6371 139/10654 5.422618409609435e-14 5.280508409909326e-13 2.0312675857411755e-13 6884/23165/6875/27243/6874/348995/57122/5431/23511/5435/5433/2960/51271/23279/23327/29082/8732/23225/2965/27183/5439/6873/9972/6881/2967/51616/8021/11198/904/51497/55746/92421/7314/137492/25978/51160/2959/404672/10015/91782/5438/10762/79720/4836/9397/79902/9883/89853/83860/2068/5902/5478/6233/7514/1025/6396/129401/6883/7936/6829/2957/25920/4928/2963/5434/5903/55706/7175/79643/5436/6878/4331/4927/8148/2966/2962/54457/8812/128866/905/2071/5901/8086/7311/93343/6880/6908/7251/1104/6882/2961/5432/22916/6877/5905/6917/81929/5440/902/9631/5430/6749/79023/5441/23636/7469/4686/7316/6872/53371/9688/8731/6879/9150/9525/2958/5437/6827/2968/138474/1022/8178/8480 123 Human_herpesvirus_1 R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 155/6371 182/10654 5.61509660982978e-14 5.430490693890171e-13 2.0889616803692622e-13 1912/23165/7068/7486/9112/6045/9212/80012/10274/348995/6613/57122/7181/23511/28996/54780/4792/3190/9759/9612/8856/1911/6790/6672/23279/1387/1789/23225/23512/165918/57332/7022/7067/7428/1107/5371/8924/4152/672/115426/9972/10499/6612/5914/8021/6117/11315/55746/7421/4286/10062/79677/7150/6670/83746/3622/1788/51564/51588/7518/3619/7153/51602/2516/8517/332/10762/5465/1655/5970/2099/79902/9656/9883/84733/3066/7157/668/7158/10155/9063/7155/7690/6396/129401/7703/9189/4791/6015/8554/7020/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/5111/4927/10521/1616/2908/8243/142/9971/1069/8086/7329/367/25942/9641/648/6095/23468/5905/81929/5893/1487/55143/9631/5468/7021/8204/3090/79023/23636/10735/3183/4306/53371/6996/23137/9688/7341/10401/2033/9126/3065/23314/6256/5987/7376/6294/8648/6304/8480/10891/7508/4193 155 Human_herpesvirus_1 R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 80/6371 84/10654 6.245976616451246e-14 5.958999312452134e-13 2.2922645334913535e-13 7124/1052/84498/4790/79718/9441/892/5469/9612/1387/6907/84246/4023/55588/10499/23054/7040/85441/9282/23097/96764/51129/7471/3952/5465/10025/5970/6604/9439/896/9370/1879/9412/9969/54797/5105/55090/1019/9440/6721/9862/1051/9442/1050/1024/9314/9968/5346/10001/23389/9443/9477/2167/51586/400569/6517/80306/8841/5468/29079/90390/6720/6837/688/9611/81857/2033/9967/7026/6256/51003/10498/948/112950/27332/8202/8648/1959/10891/219541 80 Human_herpesvirus_1 R-HSA-72202 Transport of Mature Transcript to Cytoplasm 80/6371 84/10654 6.245976616451246e-14 5.958999312452134e-13 2.2922645334913535e-13 23165/8683/6431/84271/199746/348995/57122/23511/81608/65109/23279/23225/9877/9972/8021/55746/7919/53981/6432/8563/6430/56001/80145/10762/22794/9785/11338/29107/4116/79902/9883/51213/10250/26097/51362/1977/57187/6396/129401/79228/2733/84324/4928/5903/55706/7175/7884/6428/10212/55110/84321/6429/4927/10898/10569/9295/10482/51692/8086/9939/6426/22916/10921/81929/9631/29894/79023/23636/4686/8189/53371/7307/9688/9984/10189/9775/84248/6427/8480/55339 80 Human_herpesvirus_1 R-HSA-6782135 Dual incision in TC-NER 65/6371 66/10654 7.309350636436106e-14 6.926713489025357e-13 2.664517787637606e-13 2074/5982/7507/5431/5435/9978/5433/57654/2965/5439/2067/2967/6117/10714/91603/7314/6118/404672/3150/5438/5985/2068/5984/6233/7874/5424/8451/10450/5434/5436/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/2071/51426/7311/5983/5432/56655/6917/5440/902/27339/5430/57804/5441/2072/7316/5426/5437/2033/2968/56949/9716/2073/5981/57461/1022 65 Human_herpesvirus_1 R-HSA-8878166 Transcriptional regulation by RUNX2 109/6371 121/10654 8.70988712788573e-14 8.177543953855837e-13 3.1456781572906006e-13 8454/8493/5689/7291/5682/5925/143471/5705/5709/9978/5695/9759/10413/4089/5711/5683/2101/1749/5699/5702/5696/5691/7314/5718/25/6662/5700/122706/5707/5594/3280/23198/100526737/10013/2737/865/11059/983/6714/2099/9861/2932/6502/5698/10000/5692/5713/595/5710/5719/6233/7525/10432/133522/117581/1019/3958/5706/3678/1277/891/579/5714/6772/2736/5688/5687/4322/2908/5708/4488/208/5704/23493/7311/367/860/1750/5694/5595/57154/5684/8841/5720/23462/10273/207/5690/5717/9491/6500/4086/10197/7316/10213/4094/1026/5715/5701/5685/5686/55294/23314/861/5716/581/5693/5721/10891 109 Human_herpesvirus_1 R-HSA-1169408 ISG15 antiviral mechanism 70/6371 72/10654 8.745107202777842e-14 8.177543953855837e-13 3.1456781572906006e-13 3839/23165/5335/348995/317649/57122/11274/23511/4734/23279/8672/23225/1973/3836/4599/9972/8021/7334/55746/7314/402569/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/1977/51191/6233/5610/6396/129401/4928/3838/5903/55706/7175/4600/3841/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/7318/1974/5595/3837/81929/9631/79023/23636/7316/53371/9688/5300/9775/5495/8480 70 Human_herpesvirus_1 R-HSA-2990846 SUMOylation 159/6371 188/10654 9.538583109789953e-14 8.81690475714074e-13 3.391622822934712e-13 1912/10054/23165/7068/7486/9112/6045/9212/80012/10274/348995/6613/57122/7181/23511/28996/54780/4792/3190/9759/9612/8856/1911/6790/6672/23279/1387/1789/23225/10055/23512/165918/57332/7022/7067/7428/1107/5371/8924/4152/672/115426/9972/10499/6612/5914/8021/6117/11315/55746/7421/4286/10062/79677/7150/6670/83746/3622/1788/51564/51588/7518/3619/7153/51602/2516/8517/332/10762/5465/1655/5970/2099/79902/9656/9883/84733/3066/7157/668/7158/10155/9063/7155/7690/6396/129401/7703/9189/4791/6015/8554/7020/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/5111/4927/10521/1616/2908/8243/142/9971/1069/8086/7329/367/25942/9641/648/6095/23468/5905/81929/5893/29843/1487/55143/9631/5468/7021/8204/3090/79023/23636/10735/3183/4306/53371/6996/23137/9688/7341/10401/59343/2033/9126/3065/23314/6256/5987/7376/6294/8648/6304/8480/10891/7508/4193 159 Human_herpesvirus_1 R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 102/6371 112/10654 9.55372824251086e-14 8.81690475714074e-13 3.391622822934712e-13 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6728/6173/6167/116832/6156/6143/6139/6745/3921/23478/6208/6170/6203/10952/6147/6222/6727/6184/58477/6134/6747/6731/6155/6729/6231/6142/23521/6185/6207/6726/6233/6188/200916/6122/6230/6194/6166/1650/6136/6125/6232/6160/6748/29927/6193/6210/6229/6205/28972/140801/6235/6181/7311/6223/25873/6730/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/9789/6135/6201/6161/6133 102 Human_herpesvirus_1 R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 64/6371 65/10654 1.2090037088198243e-13 1.1085150888659688e-12 4.2641552546208433e-13 2074/5982/5431/5435/9978/5433/57654/2965/5439/2967/6117/10714/91603/7314/6118/404672/3150/5438/3978/5985/2068/5984/6233/7874/5424/8451/10450/5434/5436/7515/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/2071/51426/7311/3980/5983/5432/56655/6917/5440/902/27339/5430/57804/5441/7316/5426/5437/2033/2968/56949/9716/5981/57461/1022 64 Human_herpesvirus_1 R-HSA-2682334 EPH-Ephrin signaling 86/6371 92/10654 1.7342075604844974e-13 1.5798071454220065e-12 6.077087274770803e-13 71/2042/1947/1212/23385/2051/2045/10094/2050/285220/79784/2047/2534/9475/1948/4628/8976/6093/163/284656/8997/1759/8440/8874/3265/5062/5879/1072/161/10093/5921/2046/6453/4313/2902/2041/102/6714/1943/2043/7525/1942/7410/1213/1211/1175/10109/5663/1173/2904/5747/7074/1949/10627/1945/10451/4318/160/2049/8218/10092/4067/2044/5063/6386/998/2048/10097/387/60/5058/4629/3984/28964/4627/3985/6383/10398/10552/4637/1946/10096/103910/1944/10095/1969 86 Human_herpesvirus_1 R-HSA-6807878 COPI-mediated anterograde transport 93/6371 101/10654 2.1853448021796472e-13 1.9780172183831166e-12 7.608892833499987e-13 6811/6711/11014/51807/286/347688/5861/10381/1780/9570/8655/84516/832/55738/7846/51226/9382/3630/81027/6709/10652/54732/51164/2801/377/10466/1315/8615/11316/91949/8729/23423/10376/1314/10540/51332/378/26286/26958/140735/10959/84364/22820/84617/11258/6712/1783/10382/93661/55860/830/7277/10671/966/1639/10282/6710/8775/81876/11015/347733/51143/10383/84790/10945/7280/829/1778/11070/25839/51014/83548/63908/112714/1604/1781/57731/10121/2804/9527/57511/8774/10972/381/6708/4905/9276/287/375/64689/288/22818/372 93 Human_herpesvirus_1 R-HSA-380259 Loss of Nlp from mitotic centrosomes 68/6371 70/10654 2.3328194296427717e-13 2.0847728067440466e-12 8.01955246965803e-13 7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 68 Human_herpesvirus_1 R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 68/6371 70/10654 2.3328194296427717e-13 2.0847728067440466e-12 8.01955246965803e-13 7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 68 Human_herpesvirus_1 R-HSA-8953897 Cellular responses to external stimuli 370/6371 493/10654 2.413122873284465e-13 2.1429745264639403e-12 8.243438613801947e-13 1912/23165/5689/3725/9134/2077/11065/573/4790/54468/5682/64344/7531/1915/11133/7321/51807/817/6045/8697/9530/347688/23677/27327/80012/7295/5925/3091/348995/143471/472/10381/57122/5705/79813/3576/3313/1780/7001/23511/10312/5709/9978/2114/1869/5695/3305/8655/84516/1911/832/26277/23279/4194/1031/4493/5711/5928/1432/1387/4683/10325/7846/23225/5683/3309/23512/57332/5699/126374/7428/5702/192669/9531/81027/8900/51529/4001/29945/8091/8131/2056/51434/2475/1032/3306/1030/6196/9972/10670/23411/8021/4343/6117/10587/6197/29882/3312/4217/54386/3569/64121/55746/5696/5691/7296/7314/51164/996/51182/5718/818/3303/7014/6118/51606/5601/2876/5606/7027/526/5700/122706/5707/2146/9550/2936/9114/5594/3308/84335/23198/898/10049/10013/27244/3337/10762/847/7323/1465/890/5970/9261/6667/51433/9861/79902/5598/9883/2932/84733/529/5698/5692/5713/2877/119504/10376/6195/5710/3301/10540/7157/7324/5719/64682/6233/2353/538/8726/6396/1535/129401/5600/523/201163/26523/528/405/5608/3297/57521/140735/768/6015/28956/84617/4928/4688/1019/5903/83667/55706/7175/653361/5241/11258/9448/246184/112399/1029/1783/389541/8535/84962/10382/93661/5931/58528/10294/55860/830/7013/7277/1051/1410/50488/5706/10671/8881/527/6774/1639/5714/4927/7867/64223/6119/26353/3552/10370/10524/5688/57805/5687/3310/2908/5708/347733/5602/7266/25824/6009/51143/816/6648/8086/10393/1870/5704/3326/55004/51343/7311/367/25906/3397/2034/57634/10383/84790/55662/648/5694/3304/23466/3456/2113/6416/10641/257202/7280/10728/829/2880/23523/5595/1778/1017/815/25913/81929/5684/5720/9631/3159/7290/23334/10111/4502/2878/7422/5690/57690/5717/1027/9491/545/79023/23636/10197/192670/10808/153129/112714/3490/8550/29855/4306/1781/7316/10213/10935/53371/1026/9532/54205/2289/9588/9688/10121/7415/1871/6647/8994/7322/5715/2882/5701/112398/245972/144577/5685/8649/3320/65057/5686/2033/1021/6767/25842/493869/8453/23135/10963/22824/23112/5609/10542/4689/5716/9529/4520/5599/54583/5052/1536/5693/5721/55466/2288/5034/8480/10919/51382/4193/2950/9296/23043 370 Human_herpesvirus_1 R-HSA-8878159 Transcriptional regulation by RUNX3 89/6371 96/10654 2.5089548923714163e-13 2.2141526925177747e-12 8.517241608313493e-13 5689/6046/5682/182/5705/6097/6696/5709/5695/9759/10413/4609/4089/22938/5711/1387/4088/5683/7003/5699/5702/9794/7040/3845/5696/5691/7314/5718/8463/51176/2648/5700/5707/55534/3280/84441/463/3683/865/6714/9861/8850/5698/5692/5713/595/5710/7157/5719/6233/1029/864/5706/10046/5714/6934/5688/5687/5708/5704/7311/5694/4851/3676/57154/5684/5720/2309/1499/10018/5690/5717/9491/10197/64750/7316/10213/1026/5715/5701/5685/5686/2033/861/5716/3516/5693/5721/4193 89 Human_herpesvirus_1 R-HSA-1226099 Signaling by FGFR in disease 62/6371 63/10654 3.3047910530905985e-13 2.8628005932294017e-12 1.1012413195962213e-12 5295/4893/11052/2250/5335/9530/613/5431/6776/5435/5433/11064/5439/2264/2885/9846/2252/2253/3845/3265/7750/8805/26127/5290/8823/8074/2260/5438/2249/2248/399687/2247/2246/2251/6777/1523/2963/5434/5436/9208/6774/2263/6772/2962/6654/11160/2549/5432/22916/8822/5440/5430/8817/5441/2254/4686/26281/10818/2261/5437/2255/27006 62 Human_herpesvirus_1 R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 62/6371 63/10654 3.3047910530905985e-13 2.8628005932294017e-12 1.1012413195962213e-12 5689/11065/5682/7321/8697/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/5707/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 62 Human_herpesvirus_1 R-HSA-9033241 Peroxisomal protein import 62/6371 63/10654 3.3047910530905985e-13 2.8628005932294017e-12 1.1012413195962213e-12 26063/7321/10965/10901/1384/23600/10005/8239/3417/390916/4358/5192/7314/1891/54677/26061/8528/847/7323/2053/8309/10455/5189/196743/8540/11001/6233/1610/83752/55670/373156/5264/189/3155/5193/30/122970/51/55825/1962/54363/5830/51179/54469/7311/6342/5195/3295/51268/8310/7316/7322/3416/4843/5190/5828/283927/219743/570/5194/5191/8443 62 Human_herpesvirus_1 R-HSA-909733 Interferon alpha/beta signaling 67/6371 69/10654 3.8075151855096783e-13 3.278177708499796e-12 1.2610255684999962e-12 3443/5777/5770/3107/9021/11274/3662/3106/4599/684/3133/3429/91543/4938/5696/3445/10410/9636/2634/3444/103/3434/3433/3451/3448/3661/3439/10581/3452/4940/3437/6773/7297/5781/3430/3660/3446/3135/3665/10379/3455/4600/8638/3394/3663/6772/8651/3659/25939/3440/3454/3716/3456/3105/3441/51447/54739/2537/3449/8519/3664/6041/1958/4939/6059/3669/3134 67 Human_herpesvirus_1 R-HSA-6807505 RNA polymerase II transcribes snRNA genes 71/6371 74/10654 5.453608504777027e-13 4.666966793178885e-12 1.7952548570749257e-12 6884/51585/5431/5435/23379/5433/2960/55656/5439/10302/904/65123/55197/2959/79871/5438/6667/29101/79664/25896/23248/1025/7702/6829/2957/2963/5434/26173/5436/26512/6878/55756/58490/2962/51808/8812/129685/905/5452/64859/22936/6621/6880/6908/80237/6619/6882/2961/5432/22916/6618/6877/5440/57508/5430/5451/55174/6617/5441/84524/4686/2958/5437/92105/6827/80789/57117/51593/79035/1022/8178 71 Human_herpesvirus_1 R-HSA-69615 G1/S DNA Damage Checkpoints 66/6371 68/10654 6.211512143484179e-13 5.283527196746783e-12 2.0324288307151784e-12 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/993/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/1111/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 66 Human_herpesvirus_1 R-HSA-446652 Interleukin-1 family signaling 122/6371 140/10654 8.720295274948945e-13 7.347876320247298e-12 2.8265276436913725e-12 8454/834/5689/5777/4790/5682/1511/26469/5783/27178/8878/143471/5705/5709/9978/5695/4792/59307/3606/177/5711/4088/5683/5699/5702/3654/51135/7334/3551/5696/5691/7314/3596/257397/5718/8945/1326/90865/11213/5700/122706/5707/8767/29110/23198/23118/8517/3565/5970/8809/9861/5698/5692/5713/5710/10454/5719/6233/7850/5781/5608/4791/3557/351/5782/387522/54472/5706/79155/6774/5780/5714/64127/3552/5688/5687/5708/3656/57162/5771/7189/5704/7311/5694/6416/3554/3556/1147/5778/5684/5720/6885/5604/4215/10392/5690/3553/5717/9491/6500/25930/246330/10197/4615/7316/10213/7335/4793/3146/5715/5701/23291/5685/5686/6288/6285/5716/5599/5784/57161/5693/5721 122 Human_herpesvirus_1 R-HSA-5654738 Signaling by FGFR2 70/6371 73/10654 8.794554519276158e-13 7.347876320247298e-12 2.8265276436913725e-12 5295/4893/2250/5335/54845/5431/5435/5433/8569/5439/7072/2885/7073/5518/2252/2253/3845/3265/7314/5515/5290/8823/5594/8074/5438/3185/2249/6714/2248/4670/2247/6233/2246/2251/5781/5725/2963/5434/6464/5436/673/2263/2962/80004/6654/7311/2549/5432/22916/5595/5516/8822/10253/5440/5430/3178/8817/9982/10817/5441/2254/4686/7316/26281/10818/867/5437/2255/27006/3187 70 Human_herpesvirus_1 R-HSA-8939902 Regulation of RUNX2 expression and activity 70/6371 73/10654 8.794554519276158e-13 7.347876320247298e-12 2.8265276436913725e-12 8454/5689/7291/5682/143471/5705/5709/9978/5695/5711/5683/2101/1749/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/865/11059/2099/9861/2932/6502/5698/5692/5713/5710/5719/6233/133522/5706/579/5714/6772/5688/5687/2908/5708/4488/5704/7311/860/1750/5694/57154/5684/5720/10273/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721/10891 70 Human_herpesvirus_1 R-HSA-2408557 Selenocysteine synthesis 86/6371 93/10654 9.504377904950314e-13 7.894224471641086e-12 3.036692878609513e-12 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/60678/6155/6231/6142/23521/6207/6233/51091/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 86 Human_herpesvirus_1 R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 59/6371 60/10654 1.49010845183859e-12 1.2023046479977652e-11 4.624938112172707e-12 8454/5689/9134/5682/5705/5709/5753/5695/5711/5683/5699/5702/8900/5696/5691/7314/5718/5700/5707/898/890/9861/6502/5698/5692/5713/595/5710/5719/6233/1163/1019/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/5690/5717/1027/9491/6500/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721 59 Human_herpesvirus_1 R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 59/6371 60/10654 1.49010845183859e-12 1.2023046479977652e-11 4.624938112172707e-12 8454/5689/5682/9039/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/5970/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 59 Human_herpesvirus_1 R-HSA-5610780 Degradation of GLI1 by the proteasome 59/6371 60/10654 1.49010845183859e-12 1.2023046479977652e-11 4.624938112172707e-12 8454/5689/5682/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/83737/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/8650/9861/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/2735/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Human_herpesvirus_1 R-HSA-5610783 Degradation of GLI2 by the proteasome 59/6371 60/10654 1.49010845183859e-12 1.2023046479977652e-11 4.624938112172707e-12 8454/5689/5682/1452/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/9861/2932/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/2736/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Human_herpesvirus_1 R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 59/6371 60/10654 1.49010845183859e-12 1.2023046479977652e-11 4.624938112172707e-12 8454/5689/5682/1452/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/2737/9861/2932/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Human_herpesvirus_1 R-HSA-69563 p53-Dependent G1 DNA Damage Response 64/6371 66/10654 1.6507200354458418e-12 1.3059737277039885e-11 5.0237247912275096e-12 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Human_herpesvirus_1 R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 64/6371 66/10654 1.6507200354458418e-12 1.3059737277039885e-11 5.0237247912275096e-12 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Human_herpesvirus_1 R-HSA-190236 Signaling by FGFR 81/6371 87/10654 1.655520725127653e-12 1.3059737277039885e-11 5.0237247912275096e-12 5295/4893/2250/5335/54845/5431/5435/5433/8569/9965/5439/2264/7072/2885/7073/5518/2252/2253/3845/3265/7314/5515/5290/8823/23768/5594/8074/2260/5438/3185/2249/6714/2248/4670/2247/6233/2246/2251/200734/5781/5725/2963/5434/6464/5436/673/2263/2962/23767/80004/9365/6654/7311/53834/2549/5432/22916/5595/5516/8822/10253/5440/5430/3178/8817/9982/10817/5441/2254/4686/7316/152831/26281/10818/2261/867/5437/2255/27006/3187/161742 81 Human_herpesvirus_1 R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 73/6371 77/10654 1.664839029650977e-12 1.3059737277039885e-11 5.0237247912275096e-12 5689/5682/51807/63943/347688/143471/10381/5705/5709/5695/5711/7846/5683/5699/5702/81027/5696/5691/7314/5718/5700/122706/5707/23198/983/9861/5698/5692/5713/10376/5710/7157/5719/6233/84617/51512/10382/7277/5706/9133/891/5714/5688/5687/5708/347733/22919/5704/3326/7311/10383/5347/84790/5694/7280/5684/5720/5690/5717/9491/10197/112714/7316/10213/1026/5715/5701/5685/3320/5686/5716/5693/5721 73 Human_herpesvirus_1 R-HSA-9009391 Extra-nuclear estrogen signaling 73/6371 77/10654 1.664839029650977e-12 1.3059737277039885e-11 5.0237247912275096e-12 5295/2788/374/4893/857/2770/7039/2782/3845/3265/8877/2773/2787/1839/5290/4316/5594/2069/10681/4313/2792/6714/2099/10000/2785/595/2783/2784/2771/7514/2353/255324/801/2791/805/5170/5590/6464/5747/1903/3315/4318/8503/2786/208/1956/858/3480/5595/596/685/54331/2309/59345/207/6722/1027/51764/94235/2100/1950/55970/4314/346562/2793/3320/4846/2002/1385/5296/808/3276/2790 73 Human_herpesvirus_1 R-HSA-195253 Degradation of beta-catenin by the destruction complex 77/6371 82/10654 1.7343166467864767e-12 1.3455247831112666e-11 5.175866915800011e-12 8454/5689/5682/5526/1452/143471/5705/5709/9978/5695/5711/5683/324/5699/8312/5702/5518/5696/5691/7314/5515/5718/51176/8945/5700/122706/5707/23198/5528/7091/9861/5519/2932/5698/5692/5713/5710/5719/6233/7090/10023/5706/23401/5714/6934/5688/5687/5708/5529/7088/5704/7311/5694/5516/5684/5720/1487/1499/5525/139285/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/3065/5527/1488/5716/5693/5721 77 Human_herpesvirus_1 R-HSA-9013694 Signaling by NOTCH4 77/6371 82/10654 1.7343166467864767e-12 1.3455247831112666e-11 5.175866915800011e-12 8454/5689/5682/182/23385/5705/5709/9978/5695/22938/5711/1387/4088/5683/5699/4853/5702/9794/388585/5696/5691/7314/5718/2648/5700/5707/55534/3280/84441/7534/102/9861/8850/5698/5692/5713/5710/5719/6233/2324/5663/5706/10460/10046/5714/5688/5687/5708/59/4855/5704/23493/7311/5694/4851/5684/5720/23462/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/2033/55294/5716/54567/3516/5693/5721 77 Human_herpesvirus_1 R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 117/6371 134/10654 1.9120651134934548e-12 1.475320185930469e-11 5.675154435217847e-12 5579/2153/7042/5175/3959/5578/5582/3082/29106/5267/7423/3920/374354/2244/7114/3309/3690/2162/87/10487/7040/5874/54863/350/7043/967/5054/5099/1072/7018/6678/5340/813/7094/7414/10490/83706/7044/6810/6694/3671/7273/22927/1191/3273/27154/226/2335/1/5478/94121/22915/2266/7873/5154/7076/2243/801/805/928/351/135228/51097/7424/2316/3674/5552/2157/7277/334/10447/335/51706/308/78991/6403/197/81/9948/3481/54495/5473/8407/7450/29789/10916/139322/5005/7422/5004/5196/3827/1950/2621/5216/5768/710/6647/1893/5265/7078/55664/5345/54676/2/948/88/1675/3479/5155/51368/808/213/5660/7057/5627/6814 117 Human_herpesvirus_1 R-HSA-5676590 NIK-->noncanonical NF-kB signaling 58/6371 59/10654 2.460151872081597e-12 1.8776942937184946e-11 7.2229779003931955e-12 8454/5689/5682/9039/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 58 Human_herpesvirus_1 R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 58/6371 59/10654 2.460151872081597e-12 1.8776942937184946e-11 7.2229779003931955e-12 5689/5682/143471/5705/5709/5695/84515/4998/5711/5683/990/5699/5702/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/4999/5000/5706/5714/51053/5688/5687/5708/81620/5704/23595/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 58 Human_herpesvirus_1 R-HSA-438064 Post NMDA receptor activation events 76/6371 81/10654 2.7388936842940482e-12 2.0792031624855895e-11 7.998127567038647e-12 5563/4893/51807/817/347688/53632/10381/107/7846/81027/1741/1739/6196/1740/8874/6197/3845/3265/814/5879/5923/818/5567/5594/51422/5573/2902/6714/10376/6195/5613/2906/801/2891/4747/805/5170/84617/3838/2904/2890/10382/5568/7277/10645/5566/84254/2905/5571/27330/347733/3084/816/5577/5562/10383/84790/5564/5565/5924/7280/5595/815/28964/5575/114/112714/5576/2903/4137/2066/1742/88/1385/808/8536 76 Human_herpesvirus_1 R-HSA-1236975 Antigen processing-Cross presentation 90/6371 99/10654 3.682272989338222e-12 2.7656220536944517e-11 1.063859385497493e-11 8773/5689/5682/3107/811/143471/5705/10333/5709/5695/567/3106/5711/5683/929/5699/5702/3133/3551/5696/5691/7314/5718/10952/5700/122706/5707/23198/6892/8517/6810/7096/9861/5698/5692/5713/5710/5719/6233/3685/1535/3135/4688/653361/6890/2209/5706/9554/29927/5714/5688/5687/5708/2923/695/9902/5704/4012/7311/5694/8673/3105/23643/1147/5684/5720/5690/5717/9491/10197/7099/4615/6891/7316/10213/5715/5701/9341/5685/5686/114609/4689/948/5716/3134/7097/1536/5693/5721/4360 90 Human_herpesvirus_1 R-HSA-4420097 VEGFA-VEGFR2 Pathway 90/6371 99/10654 3.682272989338222e-12 2.7656220536944517e-11 1.063859385497493e-11 5295/4893/857/5335/71/5579/5291/5578/1432/2534/9475/3690/5603/2475/6093/8440/9564/3845/3265/8877/5062/5829/5879/5290/5567/10006/57761/5921/1500/9261/6714/10810/10000/3728/7410/5580/7409/23191/3685/3791/1535/5600/6300/801/253260/805/5170/4688/5590/653361/6461/5747/5568/3315/10451/10152/7867/64223/5566/1003/10163/55845/5063/998/208/79109/2185/387/60/5058/63916/25759/558/1495/1499/4690/207/7422/10458/3708/9047/55615/10768/3320/4846/1398/4689/5296/808/1536 90 Human_herpesvirus_1 R-HSA-72187 mRNA 3'-end processing 57/6371 58/10654 4.060312349936906e-12 3.033418538683022e-11 1.1668733904580583e-11 8683/6431/84271/51585/199746/81608/1477/65109/9877/7919/53981/6432/8563/6430/11051/80145/8106/22794/9785/11338/4116/1478/51213/10250/26097/51362/23283/10914/57187/79228/84324/6428/10212/55110/84321/6429/10898/10569/9295/51692/9939/6426/22916/1479/10921/79869/29894/4686/8189/10978/7307/9984/10189/9775/84248/6427/55339 57 Human_herpesvirus_1 R-HSA-1234174 Cellular response to hypoxia 71/6371 75/10654 4.226353908049859e-12 3.124404040924817e-11 1.2018730319943387e-11 5689/5682/64344/7321/3091/143471/5705/5709/9978/5695/5711/1387/5683/5699/126374/7428/5702/2056/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/405/768/112399/84962/5706/5714/10370/5688/5687/5708/5704/7311/2034/55662/5694/5684/5720/7422/5690/5717/9491/10197/7316/10213/8994/7322/5715/5701/112398/5685/5686/2033/8453/5716/54583/5693/5721 71 Human_herpesvirus_1 R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 71/6371 75/10654 4.226353908049859e-12 3.124404040924817e-11 1.2018730319943387e-11 23165/8683/6431/84271/199746/348995/57122/23511/65109/23279/23225/9877/9972/8021/55746/7919/6432/8563/6430/56001/80145/10762/22794/9785/11338/29107/4116/79902/9883/51213/10250/26097/51362/57187/6396/129401/79228/2733/84324/4928/5903/55706/7175/6428/10212/55110/84321/6429/4927/10569/9295/10482/8086/9939/6426/22916/10921/81929/9631/79023/23636/4686/53371/7307/9688/9984/10189/9775/84248/6427/8480 71 Human_herpesvirus_1 R-HSA-187037 Signaling by NTRK1 (TRKA) 75/6371 80/10654 4.321763994534401e-12 3.1782972709805075e-11 1.2226042879274952e-11 5295/9252/4893/5335/5291/1848/1785/5605/5898/1432/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5515/5607/161/5290/3667/5899/1849/5594/5528/9261/6714/5519/5598/4208/4914/6195/1213/1211/5600/1175/6300/1846/1173/116/6464/160/673/6774/26052/7867/2889/6654/5900/387/7529/5595/25759/5516/1845/4915/5604/4205/57498/10818/466/53358/4803/2002/1398/1385/5906/5296 75 Human_herpesvirus_1 R-HSA-9612973 Autophagy 105/6371 119/10654 6.0188166277199816e-12 4.403403667533997e-11 1.6938693100100958e-11 9927/5563/2670/65018/1459/1915/27243/9140/8878/1460/53632/84938/5116/115201/9474/8655/1457/51271/3043/3920/10325/29082/9776/55054/55062/2475/84557/10670/3312/11315/64121/92421/7314/137492/64422/139341/25978/51160/60673/9821/51422/7249/10533/10013/91782/79720/192111/440738/6714/8408/89853/84971/123/55669/6233/9804/30849/57521/140735/28956/7405/79643/389541/79065/22863/58528/7416/26100/64223/5571/128866/6009/3326/55004/7311/5562/93343/11345/55626/7251/5564/5565/401505/7248/11337/10452/1080/64419/153129/7316/83734/11152/5289/8678/56993/10226/8649/3320/81631/10542/23710/54543/200894/7431/23192 105 Human_herpesvirus_1 R-HSA-442755 Activation of NMDA receptors and postsynaptic events 85/6371 93/10654 7.0949416493538946e-012 5.1639472210761337e-11 1.9864296750225772e-11 5563/4893/51807/817/347688/53632/10381/107/7846/81027/1741/1739/6196/1740/8874/6197/8825/3845/3265/814/5879/5923/818/5567/5594/51422/2892/5573/2902/6714/22843/10376/6195/5613/2906/801/2891/4747/57576/805/5170/84617/3838/8573/2904/2890/10382/5568/7277/10645/55327/5566/84254/2905/5571/27330/347733/3084/816/5577/2893/5562/10383/84790/5564/5565/5924/7280/5595/64130/815/28964/5575/114/112714/5576/2903/4137/2066/9647/1742/88/1385/808/8536 85 Human_herpesvirus_1 R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 55/6371 56/10654 1.1048381752275283e-11 7.959344405210561e-11 3.061742741232033e-11 5689/5682/26986/143471/5705/5709/5695/5711/5683/5699/5702/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/9861/5698/5692/5713/1981/5710/5719/6233/3315/5706/5714/5688/5687/5708/5704/7311/5694/3304/5684/5720/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 55 Human_herpesvirus_1 R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 55/6371 56/10654 1.1048381752275283e-11 7.959344405210561e-11 3.061742741232033e-11 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/51009/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/9861/5698/5692/5713/5710/5719/6233/27248/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 55 Human_herpesvirus_1 R-HSA-114608 Platelet degranulation 112/6371 129/10654 1.3061190036313374e-11 9.36162453364187e-11 3.601161666437457e-11 2153/7042/5175/3959/3082/29106/5267/7423/3920/374354/2244/7114/3309/3690/2162/87/10487/7040/5874/54863/350/7043/967/5054/5099/1072/7018/6678/5340/813/7094/7414/10490/83706/7044/6694/3671/7273/22927/1191/3273/27154/226/2335/1/5478/94121/22915/2266/7873/5154/7076/2243/801/805/928/351/135228/51097/7424/2316/3674/5552/2157/7277/334/10447/335/51706/308/78991/6403/197/81/9948/3481/54495/5473/8407/7450/29789/10916/139322/5005/7422/5004/5196/3827/1950/2621/5216/5768/710/6647/1893/5265/7078/55664/5345/54676/2/948/88/1675/3479/5155/51368/808/213/5660/7057/5627 112 Human_herpesvirus_1 R-HSA-199992 trans-Golgi Network Vesicle Budding 68/6371 72/10654 1.699501493842061e-11 1.2119677319722172e-10 4.6621093610978394e-11 27131/8773/8906/162/1176/27243/5286/1212/1174/1785/8546/11154/7037/3482/408/6456/7164/3312/1362/26258/25977/10618/6643/10053/6810/55330/8301/9146/8729/4074/2495/388552/152503/6844/54885/1213/2580/1211/23431/8907/351/84062/9685/9179/9026/8775/9829/8905/51429/8673/23557/2512/164/1777/130340/6272/1522/2799/2804/7163/286451/9698/5878/81567/10717/6845/375/4952 68 Human_herpesvirus_1 R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 48/6371 48/10654 1.779593880993232e-11 1.2627068140514791e-10 4.8572887733007547e-11 5295/5777/1437/5291/6776/3558/3717/2534/3563/2885/9846/1399/7314/3635/5290/1439/7534/3718/3567/6233/7525/7409/6777/5781/3562/6464/1438/6850/5566/8503/2889/4067/29760/3636/6654/7006/3716/7311/5293/3561/3568/7316/3560/3055/867/1398/5296/3559 48 Human_herpesvirus_1 R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 54/6371 55/10654 1.8215105785879463e-11 1.279588525853821e-10 4.922228114958787e-11 8454/5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/26271/5706/5714/5688/5687/5708/5704/51343/7311/5694/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 54 Human_herpesvirus_1 R-HSA-8941858 Regulation of RUNX3 expression and activity 54/6371 55/10654 1.8215105785879463e-11 1.279588525853821e-10 4.922228114958787e-11 5689/5682/5705/5709/5695/5711/5683/5699/5702/7040/5696/5691/7314/5718/5700/5707/865/6714/9861/5698/5692/5713/5710/5719/6233/1029/864/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/2033/5716/5693/5721/4193 54 Human_herpesvirus_1 R-HSA-8943724 Regulation of PTEN gene transcription 59/6371 61/10654 1.8831671917934604e-11 1.3163525122833496e-10 5.063649145208055e-11 1912/3725/6591/1822/9112/6045/80012/1911/5928/10325/23512/57332/1107/2475/1386/10670/64121/23186/2146/51564/5594/84232/7101/84733/57459/3066/7157/8726/57521/6015/28956/389541/9219/8535/5931/58528/1108/2122/64223/10014/54815/6009/55004/57504/648/23466/53615/5595/8841/5468/5978/153129/57167/1958/8649/6615/3065/23028/10542 59 Human_herpesvirus_1 R-HSA-1632852 Macroautophagy 86/6371 95/10654 2.0071410617254905e-11 1.3961000882543805e-10 5.370416322791564e-11 9927/5563/65018/1459/27243/9140/8878/1460/53632/84938/115201/9474/8655/1457/10325/29082/9776/55054/55062/2475/84557/10670/3312/64121/92421/7314/64422/139341/25978/60673/9821/51422/7249/10533/91782/192111/440738/6714/8408/84971/123/55669/6233/9804/30849/57521/140735/28956/7405/79643/389541/79065/22863/58528/7416/26100/64223/5571/128866/6009/55004/7311/5562/11345/55626/5564/5565/401505/7248/11337/10452/64419/153129/7316/83734/11152/5289/8678/56993/10226/8649/81631/10542/23710/54543/23192 86 Human_herpesvirus_1 R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 63/6371 66/10654 2.4491791000562435e-11 1.695216122195792e-10 6.521034136372661e-11 5689/5682/64344/7321/3091/143471/5705/5709/9978/5695/5711/5683/5699/126374/7428/5702/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/112399/84962/5706/5714/5688/5687/5708/5704/7311/2034/5694/5684/5720/5690/5717/9491/10197/7316/10213/8994/7322/5715/5701/112398/5685/5686/8453/5716/54583/5693/5721 63 Human_herpesvirus_1 R-HSA-194138 Signaling by VEGF 95/6371 107/10654 2.732878612125304e-11 1.882353463571185e-10 7.240900456260113e-11 5295/4893/857/5335/71/5579/5291/5578/7423/1432/2534/9475/3690/5603/2475/6093/8440/9564/3845/3265/8877/5062/5829/5879/5290/5567/10006/57761/5921/1500/9261/6714/2321/10810/10000/3728/7410/5580/2324/7409/23191/3685/3791/1535/5600/6300/801/253260/805/5170/4688/5590/653361/6461/5747/7424/5568/3315/10451/10152/7867/64223/5566/1003/10163/55845/5063/998/208/79109/2185/387/60/5058/63916/25759/558/1495/1499/4690/207/7422/10458/3708/9047/55615/10768/3320/4846/1398/4689/5228/5296/808/1536 95 Human_herpesvirus_1 R-HSA-2132295 MHC class II antigen presentation 107/6371 123/10654 2.881220742338236e-11 1.935492125577533e-10 7.445310398076688e-11 64837/162/11127/51807/10484/1174/347688/3798/1785/10381/1780/3115/1509/8655/84516/3109/832/285643/3113/10112/972/7846/5476/3117/9632/81027/6456/11004/3112/163/1759/3127/81930/51164/161/3797/10053/29127/22872/3111/3796/10437/89953/56992/83547/10376/10540/3835/147700/1213/1211/9493/6396/1175/7879/140735/8907/1508/3831/3120/1173/84617/11258/6712/1783/10382/10802/93661/821/55860/830/3123/3832/7277/160/10671/3122/1639/26052/26153/1062/347733/51143/9871/10383/24137/84790/84643/8905/22920/1075/7280/829/1778/114876/164/9371/3119/10120/112714/130340/1781/5641/10121/3799/375/10427 107 Human_herpesvirus_1 R-HSA-167161 HIV Transcription Initiation 47/6371 47/10654 2.9848438165236e-11 1.935492125577533e-10 7.445310398076688e-11 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_herpesvirus_1 R-HSA-167162 RNA Polymerase II HIV Promoter Escape 47/6371 47/10654 2.9848438165236e-11 1.935492125577533e-10 7.445310398076688e-11 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_herpesvirus_1 R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 47/6371 47/10654 2.9848438165236e-11 1.935492125577533e-10 7.445310398076688e-11 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Human_herpesvirus_1 R-HSA-6802949 Signaling by RAS mutants 47/6371 47/10654 2.9848438165236e-11 1.935492125577533e-10 7.445310398076688e-11 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Human_herpesvirus_1 R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 47/6371 47/10654 2.9848438165236e-11 1.935492125577533e-10 7.445310398076688e-11 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Human_herpesvirus_1 R-HSA-73776 RNA Polymerase II Promoter Escape 47/6371 47/10654 2.9848438165236e-11 1.935492125577533e-10 7.445310398076688e-11 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_herpesvirus_1 R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 47/6371 47/10654 2.9848438165236e-11 1.935492125577533e-10 7.445310398076688e-11 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_herpesvirus_1 R-HSA-75953 RNA Polymerase II Transcription Initiation 47/6371 47/10654 2.9848438165236e-11 1.935492125577533e-10 7.445310398076688e-11 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_herpesvirus_1 R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 47/6371 47/10654 2.9848438165236e-11 1.935492125577533e-10 7.445310398076688e-11 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_herpesvirus_1 R-HSA-9649948 Signaling downstream of RAS mutants 47/6371 47/10654 2.9848438165236e-11 1.935492125577533e-10 7.445310398076688e-11 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Human_herpesvirus_1 R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 53/6371 54/10654 3.001931837829177e-11 1.935492125577533e-10 7.445310398076688e-11 2074/7507/5431/5435/9978/5433/10980/57654/2965/5439/10987/2967/91603/7314/404672/3150/5438/10920/2068/6233/7874/8451/10450/5434/5436/8450/4331/2966/1161/1642/2071/2873/7311/8533/5432/51138/9318/6917/5440/902/27339/5430/5441/7316/64708/5437/2033/2968/56949/9716/57461/1022/50813 53 Human_herpesvirus_1 R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 53/6371 54/10654 3.001931837829177e-11 1.935492125577533e-10 7.445310398076688e-11 8454/5689/5682/143471/5705/5709/9978/5695/6790/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/23194/5693/5721 53 Human_herpesvirus_1 R-HSA-9604323 Negative regulation of NOTCH4 signaling 53/6371 54/10654 3.001931837829177e-11 1.935492125577533e-10 7.445310398076688e-11 8454/5689/5682/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/5707/7534/9861/5698/5692/5713/5710/5719/6233/5706/10460/5714/5688/5687/5708/4855/5704/7311/5694/5684/5720/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721 53 Human_herpesvirus_1 R-HSA-400253 Circadian Clock 66/6371 70/10654 4.27990904733301e-11 2.746923443106459e-10 1.0566665399157098e-10 8454/79718/5936/28999/3091/5469/1628/1387/150094/6907/2155/5499/10499/23054/1386/9575/23411/9572/85441/96764/7314/5054/8945/10135/1454/5465/64784/4208/6604/56938/6233/8864/1453/5500/5187/26224/10743/1374/1407/4783/406/4209/5501/8553/2908/1390/7311/23373/6095/8841/8204/4862/6500/200186/1408/6720/7316/9611/2033/79365/6256/10498/1385/8648/551/10891 66 Human_herpesvirus_1 R-HSA-674695 RNA Polymerase II Pre-transcription Events 77/6371 84/10654 4.9127454072986036e-11 3.1388219525364833e-10 1.2074192094146604e-10 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/11198/904/51497/4300/80349/2959/404672/5438/83860/2068/1025/23168/55677/6883/7936/6829/2957/123169/25920/85403/2963/5434/5436/9646/6878/79577/4331/8148/2966/2962/4298/54457/8812/905/2071/27125/6880/6908/6882/2961/5432/22916/55840/6877/6917/5440/902/6830/5430/6749/5441/7469/4686/6872/6879/9150/54623/2958/5437/6827/2968/138474/1022/8178 77 Human_herpesvirus_1 R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 57/6371 59/10654 4.966488596881302e-11 3.1588657201785577e-10 1.2151295002326943e-10 6227/6206/1965/6234/27335/6191/8668/6224/8662/26986/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1978/1968/6230/8669/6194/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 57 Human_herpesvirus_1 R-HSA-166520 Signaling by NTRKs 90/6371 101/10654 5.75457772107807e-11 3.643705713974096e-10 1.4016342242512553e-10 5295/627/9252/4893/5335/5291/1848/1785/5605/5898/1432/2534/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5879/5515/5607/161/5290/3667/5899/1849/5594/5528/9261/6714/5519/5598/4208/4909/4914/6195/1213/1211/5600/1175/6300/5781/1846/25920/4908/1173/116/6464/2904/7074/160/673/6774/26052/7867/2889/6654/5900/387/2549/1020/4916/7529/5595/25759/5516/1845/4915/5604/10817/4205/57498/10818/466/53358/4803/2002/1398/1385/5906/8851/5296/581 90 Human_herpesvirus_1 R-HSA-8948751 Regulation of PTEN stability and activity 65/6371 69/10654 6.783059309404165e-11 4.275749886106554e-10 1.6447643814156716e-10 5689/5682/1459/1460/143471/5705/5709/5695/1457/4734/11060/5711/5683/5699/2444/5702/8975/5696/5691/7314/5718/5700/122706/5707/23198/9861/81847/5698/10000/5692/5713/5710/5719/6233/331/23608/5706/8658/5714/5688/5687/5708/208/5704/7311/5694/5684/5720/10273/207/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5728/5987/5716/5693/5721 65 Human_herpesvirus_1 R-HSA-72649 Translation initiation complex formation 56/6371 58/10654 8.05806705551008e-11 4.956487936517857e-10 1.9066257456711006e-10 6227/6206/1965/6234/27335/6191/8668/6224/8662/26986/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1968/6230/8669/6194/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 56 Human_herpesvirus_1 R-HSA-72702 Ribosomal scanning and start codon recognition 56/6371 58/10654 8.05806705551008e-11 4.956487936517857e-10 1.9066257456711006e-10 6227/6206/1965/6234/27335/6191/8668/6224/8662/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1968/6230/8669/6194/1983/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 56 Human_herpesvirus_1 R-HSA-180534 Vpu mediated degradation of CD4 51/6371 52/10654 8.143804541587413e-11 4.956487936517857e-10 1.9066257456711006e-10 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/920/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_herpesvirus_1 R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 51/6371 52/10654 8.143804541587413e-11 4.956487936517857e-10 1.9066257456711006e-10 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_herpesvirus_1 R-HSA-69610 p53-Independent DNA Damage Response 51/6371 52/10654 8.143804541587413e-11 4.956487936517857e-10 1.9066257456711006e-10 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_herpesvirus_1 R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 51/6371 52/10654 8.143804541587413e-11 4.956487936517857e-10 1.9066257456711006e-10 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_herpesvirus_1 R-HSA-72165 mRNA Splicing - Minor Pathway 51/6371 52/10654 8.143804541587413e-11 4.956487936517857e-10 1.9066257456711006e-10 6633/6431/4904/51639/23450/5431/5435/5433/9416/8233/23020/5439/9410/10907/10262/6432/83443/10081/5438/9343/6636/2963/6635/5434/6632/24148/154007/5436/6637/55954/57819/2962/6426/5432/22916/23451/5440/55599/5430/85437/11325/5441/79622/10594/4686/5437/11066/6634/6427/10992/6628 51 Human_herpesvirus_1 R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 51/6371 52/10654 8.143804541587413e-11 4.956487936517857e-10 1.9066257456711006e-10 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/2932/5698/5692/5713/595/5710/5719/6233/1019/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_herpesvirus_1 R-HSA-5688426 Deubiquitination 229/6371 297/10654 1.2669502955650393e-10 7.67782754222247e-10 2.9534508810099857e-10 5689/221937/645836/5682/79594/7419/10474/7321/4738/7375/9817/10445/91833/6478/3091/143471/100287513/5705/11274/55031/8239/5709/5695/4792/9986/11047/4609/392188/4194/4089/100287144/55432/5711/7347/4088/114803/5683/324/408/55777/64135/5699/8724/8312/100287327/5702/8900/8975/57599/377630/672/6881/51616/7187/7040/728386/7345/3054/1540/100287404/5696/5691/7314/5718/3607/6314/90865/2648/5700/122706/5707/8027/8737/83444/8767/171023/55611/100287364/51720/57646/23198/63967/9101/8517/86/993/890/7417/80124/983/4092/2099/1643/9861/23586/81847/64426/100287441/8850/7128/29844/7046/6502/5698/9146/5692/5713/5710/10454/8473/7157/10869/9958/8313/5719/6233/100287478/9804/55593/84282/93973/10318/23770/8607/7874/100287178/5886/100287238/10600/114785/23326/51651/8237/4303/409/330/5706/4287/27005/7706/580/7416/79155/25862/9738/8658/84132/5714/79589/55288/27430/64127/5688/9097/5687/8078/5708/125476/4087/63891/84749/7189/5704/7048/7311/367/114548/387/60/29761/5694/7528/9960/23358/23032/5684/8295/5720/10617/7186/56957/6885/991/51377/10392/5690/2625/57506/5717/9491/4086/1080/57695/10197/64750/29086/7316/10213/8314/55252/8678/9100/7415/5715/283899/3416/5701/329/79913/9099/5685/54617/5686/2033/221656/5728/10868/5716/79184/78990/5887/9736/54764/5693/154/10254/5721/100287205/4193 229 Human_herpesvirus_1 R-HSA-4641258 Degradation of DVL 55/6371 57/10654 1.3065788167375203e-10 7.850592720142037e-10 3.0199089336464073e-10 5689/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/1855/5696/5691/7314/5718/5700/122706/5707/1856/23198/9861/5698/5692/5713/5710/5719/6233/1857/5706/5714/5688/5687/5708/51339/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/23072/5693/5721 55 Human_herpesvirus_1 R-HSA-69541 Stabilization of p53 55/6371 57/10654 1.3065788167375203e-10 7.850592720142037e-10 3.0199089336464073e-10 5689/5682/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/51230/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721/4193 55 Human_herpesvirus_1 R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 67/6371 72/10654 1.6079786494097402e-10 9.620618021044718e-10 3.700789398284684e-10 8773/55763/5563/71/7531/11127/51807/10971/347688/7533/2810/53632/10381/60412/5898/7846/81027/51552/23433/5879/51422/4644/7534/6810/5872/4641/10376/11336/6844/9882/79058/801/4218/805/84617/7532/57186/10382/7277/5571/347733/208/5867/4012/10383/60/84790/5564/5565/22920/7280/7529/55770/23265/6517/10890/9371/10640/4627/207/112714/8766/149371/9847/808/54536/6814 67 Human_herpesvirus_1 R-HSA-432722 Golgi Associated Vesicle Biogenesis 54/6371 56/10654 2.117166546931984e-10 1.2613667359780428e-9 4.852133858391756e-10 27131/162/1176/5286/1174/1785/8546/7037/3482/408/6456/7164/3312/1362/26258/25977/10618/6643/10053/55330/8301/2495/388552/152503/6844/54885/1213/2580/1211/23431/8907/84062/9685/9026/8775/9829/8905/51429/8673/23557/2512/164/130340/6272/2804/7163/286451/9698/5878/81567/10717/6845/375/4952 54 Human_herpesvirus_1 R-HSA-1227986 Signaling by ERBB2 49/6371 50/10654 2.2056430600117972e-10 1.3030828454965095e-9 5.012604355719389e-10 5295/4893/5335/26469/5578/2064/5753/145957/2534/4145/9542/2885/3845/3265/7314/1839/5290/2065/2069/9101/6714/10000/6233/7525/5580/1729/6464/5782/10193/3084/2886/208/6654/10718/7311/387/1956/2549/11140/8065/685/10273/207/7316/1950/51072/3320/2066/5581 49 Human_herpesvirus_1 R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 49/6371 50/10654 2.2056430600117972e-10 1.3030828454965095e-9 5.012604355719389e-10 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 49 Human_herpesvirus_1 R-HSA-5655253 Signaling by FGFR2 in disease 43/6371 43/10654 2.3607350490841895e-10 1.383136053654305e-9 5.320547216979436e-10 5295/4893/2250/5335/5431/5435/5433/5439/2885/2252/2253/3845/3265/5290/8823/8074/5438/2249/2248/2247/2246/2251/2963/5434/5436/2263/2962/6654/2549/5432/22916/8822/5440/5430/8817/5441/2254/4686/26281/10818/5437/2255/27006 43 Human_herpesvirus_1 R-HSA-5696395 Formation of Incision Complex in GG-NER 43/6371 43/10654 2.3607350490841895e-10 1.383136053654305e-9 5.320547216979436e-10 6613/7507/9978/85015/2965/2067/2967/6612/6117/7334/7314/6118/404672/9557/1643/2068/6233/5886/8451/8554/8450/4331/2966/6119/1642/142/2071/1069/7329/7311/10038/902/7336/2072/54778/7316/7341/10401/2968/5887/2073/1022/7508 43 Human_herpesvirus_1 R-HSA-3371556 Cellular response to heat stress 80/6371 89/10654 2.4697380895573094e-10 1.4410207365516201e-9 5.543213806922887e-10 23165/573/7531/1915/817/9530/348995/472/57122/3313/23511/3305/23279/1387/23225/3309/9531/2475/3306/9972/23411/8021/6117/3312/55746/51182/818/3303/6118/5594/3308/84335/10049/10013/3337/10762/9261/79902/9883/2932/6396/129401/3297/57521/4928/5903/55706/7175/1410/4927/64223/6119/26353/57805/3310/7266/816/8086/3326/3304/10728/5595/815/81929/9631/545/79023/23636/10808/53371/9532/9688/7415/3320/2033/6767/22824/9529/2288/8480 80 Human_herpesvirus_1 R-HSA-5678895 Defective CFTR causes cystic fibrosis 58/6371 61/10654 2.5794636778887605e-10 1.4988488531600534e-9 5.765662801778646e-10 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/51009/5696/5691/7314/5718/5700/122706/5707/10956/79139/91445/23198/9861/5698/5692/5713/5710/5719/6233/27248/6048/5706/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 58 Human_herpesvirus_1 R-HSA-5610787 Hedgehog 'off' state 98/6371 113/10654 2.928589628673243e-10 1.6947412113469748e-9 6.519207283845528e-10 8454/5689/57728/5682/11127/1452/51684/143471/10381/5705/5709/9978/5695/107/5711/7846/5683/5699/5702/81027/83737/5696/5691/7314/5718/8945/79659/5700/122706/5707/5567/23198/112/5573/2737/5727/8650/111/9861/2932/5698/5692/5713/10376/5710/5719/6233/23322/196883/115/84617/54903/10382/79809/5568/7277/5706/113/5714/5566/2736/5688/5687/5708/347733/5577/5704/7311/10383/84790/5694/7280/109/5684/5720/2735/5575/5690/5717/9491/6500/57539/114/7289/10197/108/7316/10213/2778/5715/5701/5576/5685/5686/5716/8481/5693/5721 98 Human_herpesvirus_1 R-HSA-4641257 Degradation of AXIN 53/6371 55/10654 3.4283095207721517e-10 1.975825731971542e-9 7.600462782893363e-10 5689/5682/143471/5705/5709/5695/5711/5683/5699/8312/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/81847/5698/5692/5713/5710/8313/5719/6233/5706/8658/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/5716/5693/5721 53 Human_herpesvirus_1 R-HSA-177929 Signaling by EGFR 48/6371 49/10654 3.6274787962655533e-10 2.0821138456613665e-9 8.009324171472083e-10 5295/374/4893/5335/7039/55824/6456/6868/30011/2885/8874/3845/3265/10252/5829/7314/1839/5290/8027/2060/2069/102/6714/9146/6455/1445/6233/29924/255324/5781/6464/5782/5796/998/6654/7311/1956/2549/10253/685/26018/58513/7316/1950/867/5774/10254/6457 48 Human_herpesvirus_1 R-HSA-3858494 Beta-catenin independent WNT signaling 122/6371 146/10654 3.8321252933351955e-10 2.1906724348944518e-9 8.426919460306673e-10 2788/5689/5579/5682/5331/5578/1212/5582/27327/143471/5705/5530/5709/5695/5881/5711/5683/5699/2782/5702/192669/57216/1855/163/4343/3845/5696/5691/4920/7314/5879/2787/5718/51176/161/51701/5700/122706/5707/1856/8322/23198/10681/7471/2792/9861/5698/5880/5692/5713/2785/2783/2784/5710/5719/6233/7474/1857/1213/1211/7855/1175/26523/801/2791/805/1173/144165/4772/409/5706/160/5714/6934/5688/5687/4919/23236/5708/2786/5704/7311/387/5694/57154/27161/815/5684/5720/54331/6885/1499/59345/5690/5532/57690/5717/9491/51764/94235/3708/10197/192670/64750/7316/10213/55970/5216/5715/5701/2793/5685/5686/5534/23112/23513/5716/808/5693/5721/6259/2790 122 Human_herpesvirus_1 R-HSA-74751 Insulin receptor signalling cascade 52/6371 54/10654 5.547547697485402e-10 3.1585231245360432e-9 1.2149977130316076e-9 5295/3643/4893/2250/5291/9965/2264/3630/2885/8660/9846/2252/2253/3845/3265/2323/54106/5290/3667/8823/5594/8074/57761/2260/2249/2248/2247/2246/2251/5781/30849/5170/6464/2322/2263/208/9365/6654/2549/5595/8822/8817/2254/152831/5289/26281/10818/2261/2255/27006/5296/2887 52 Human_herpesvirus_1 R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 71/6371 78/10654 6.498557696031442e-10 3.6851258902796774e-9 1.417567436547125e-9 3443/4790/80143/7321/9140/79132/9474/4792/177/3093/1387/64135/83737/7187/1540/3551/7314/3445/8737/29110/4214/9636/841/8517/3444/8887/7323/5970/23586/7128/3451/3448/3661/3439/51191/6233/10010/55593/84282/8772/3452/4791/3446/3665/351/54476/7706/843/3440/9246/7189/7311/7318/5094/9641/3456/1147/3441/7186/57506/3449/84166/7316/4793/3146/7322/2033/6288/54941/6285/5300 71 Human_herpesvirus_1 R-HSA-983189 Kinesins 56/6371 59/10654 6.576753161658051e-10 3.7145501857044668e-9 1.428886160596023e-9 64837/11127/51807/347688/3798/10381/285643/10112/64147/7846/81027/11004/10749/81930/113220/3797/29127/55605/3796/124602/55614/89953/56992/10376/3835/147700/3833/9493/3831/84617/9585/10382/3832/7277/23303/26153/1062/146909/347733/90990/23046/10383/24137/84790/84643/22920/7280/55582/9371/23095/112714/547/3834/55083/3799/221458 56 Human_herpesvirus_1 R-HSA-5654743 Signaling by FGFR4 41/6371 41/10654 6.636572570800486e-10 3.7185874880834464e-9 1.4304392007239144e-9 5295/4893/5335/8569/9965/2264/2885/5518/2253/3845/3265/7314/5515/5290/8823/5594/8074/2249/6714/2247/6233/2246/2251/5781/6464/673/6654/7311/2549/5595/5516/8822/10253/8817/10817/2254/7316/152831/26281/10818/867 41 Human_herpesvirus_1 R-HSA-5696400 Dual Incision in GG-NER 41/6371 41/10654 6.636572570800486e-10 3.7185874880834464e-9 1.4304392007239144e-9 5982/7507/9978/2965/2067/2967/6117/10714/7314/6118/404672/9557/1643/5985/2068/5984/6233/5424/8451/54107/8450/5425/5111/2966/6119/5427/1642/142/2071/51426/7311/5983/10038/56655/57804/2072/7316/5426/2968/2073/5981 41 Human_herpesvirus_1 R-HSA-2428924 IGF1R signaling cascade 51/6371 53/10654 8.970321030245401e-10 5.006360986050002e-9 1.9258105477872383e-9 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/2323/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/8471/2246/2251/5781/30849/5170/6464/2322/2263/3481/208/9365/6654/2549/3480/8822/8817/2254/152831/5289/26281/10818/2261/2255/27006/3479/5296 51 Human_herpesvirus_1 R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 46/6371 47/10654 9.798121458490563e-10 5.446829724168769e-9 2.0952468597518155e-9 8454/79718/892/3091/9978/9759/9612/4609/22938/1387/6907/9794/388585/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/7091/8850/3066/6233/7090/10046/1024/10014/26508/7088/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 46 Human_herpesvirus_1 R-HSA-5674135 MAP2K and MAPK activation 40/6371 40/10654 1.1126296203834529e-9 6.160913819535041e-9 2.369935538154228e-9 4893/71/84292/5908/22866/5605/5037/2244/54756/3690/408/5894/8826/4140/3845/3265/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/28956/283455/3674/409/673/7450/60/7529/5595/5604/54518/10256/8649/5906 40 Human_herpesvirus_1 R-HSA-448424 Interleukin-17 signaling 66/6371 72/10654 1.2503467860308862e-9 6.896443991701607e-9 2.6528739374668474e-9 8454/3605/3725/9252/4790/1848/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/23118/8517/5528/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/1846/387522/79155/7867/64127/5602/3656/7189/112744/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/7316/7335/4205/466/23291/2002/5609/1385/5599 66 Human_herpesvirus_1 R-HSA-2428928 IRS-related events triggered by IGF1R 50/6371 52/10654 1.4494064362981992e-9 7.932410418810299e-9 3.0513819711541032e-9 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/2323/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/8471/2246/2251/5781/30849/5170/2322/2263/3481/208/9365/6654/2549/3480/8822/8817/2254/152831/5289/26281/10818/2261/2255/27006/3479/5296 50 Human_herpesvirus_1 R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/6371 52/10654 1.4494064362981992e-9 7.932410418810299e-9 3.0513819711541032e-9 5689/5682/143471/472/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Human_herpesvirus_1 R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 49/6371 51/10654 2.3401105527789437e-9 1.2757668341790999e-8 4.907527109262081e-9 6227/6206/1965/6234/27335/6191/8668/6224/8662/6202/6218/3921/8665/6208/6203/8666/6222/8667/6231/8663/8894/6207/6233/51386/6188/1968/6230/8669/6194/6232/6193/6210/6229/6205/6235/6223/8664/6187/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 49 Human_herpesvirus_1 R-HSA-390466 Chaperonin-mediated protein folding 83/6371 95/10654 3.1393037521964376e-9 1.704883422346681e-8 6.558221603778793e-9 2788/9134/1459/2770/51807/10528/1460/10381/10576/1457/7846/7411/2782/81027/10574/6468/10564/54461/10693/8877/2773/5201/2787/5204/10575/10681/898/10517/2792/10471/26985/2785/10376/2783/26190/2784/10238/7157/2771/83752/2791/5202/26224/84617/2629/2781/8237/10382/7277/63971/6774/26272/26270/347733/55135/5082/2786/10383/60/84790/22948/7280/84261/10694/8841/54331/22803/59345/5203/51764/94235/2779/112714/7203/908/55970/346562/2793/6950/55294/6499/26234/2790 83 Human_herpesvirus_1 R-HSA-6809371 Formation of the cornified envelope 108/6371 129/10654 3.160090608036757e-9 1.709596911321035e-8 6.576353110493918e-9 3713/3872/125115/1823/1824/3855/353131/353141/353134/5266/3852/6701/3861/390792/7051/3880/25818/8687/147183/353142/826/353139/192666/3848/823/6706/196374/162605/3888/1475/342574/6704/26239/64065/3857/23581/8502/5317/353135/7062/3728/140807/51350/353133/112802/54474/6700/149018/121391/353137/3860/3892/199834/144501/1828/6699/3856/2125/338785/448835/1825/3866/5318/1041/1829/8689/3884/353143/6707/353140/374454/3885/25984/6705/1832/3853/3875/286887/3849/6768/3887/3859/11187/84648/3881/3889/353145/319101/5652/3890/126638/353288/3886/9119/254910/353144/3854/5493/8688/3891/3882/6703/353132/3850/3858/6698/3868/3883 108 Human_herpesvirus_1 R-HSA-5654736 Signaling by FGFR1 48/6371 50/10654 3.775153646635629e-9 2.03454845383569e-8 7.826353080208857e-9 5295/4893/2250/5335/8569/2885/5518/2253/3845/3265/7314/5515/5290/23768/5594/8074/2260/2249/6714/2248/2247/6233/2246/2251/200734/5781/6464/673/23767/9365/6654/7311/53834/2549/5595/5516/8822/10253/8817/10817/2254/7316/26281/10818/867/2255/27006/161742 48 Human_herpesvirus_1 R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 52/6371 55/10654 4.228100942718188e-9 2.2613933829992734e-8 8.698963662051775e-9 834/4790/7295/29108/1432/10628/5603/83737/3654/7334/1540/3551/7314/257397/8767/23118/841/8517/5970/24145/7128/837/598/10454/6233/5600/6300/5608/4791/351/387522/330/64127/3656/7189/3326/4210/7311/114548/1147/9447/596/6885/842/10392/10910/835/58484/7316/7335/22861/329 52 Human_herpesvirus_1 R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 52/6371 55/10654 4.228100942718188e-9 2.2613933829992734e-8 8.698963662051775e-9 51807/347688/10381/1780/3305/8655/84516/832/7846/81027/3306/3312/51164/3303/3337/10376/3301/10540/140735/84617/5241/11258/1783/10382/93661/10294/55860/830/7277/10671/1639/2908/347733/51143/3326/367/10383/84790/3304/7280/10728/829/1778/112714/4306/1781/2289/10121/3320/10963/55466/2288 52 Human_herpesvirus_1 R-HSA-451927 Interleukin-2 family signaling 43/6371 44/10654 4.333465016121194e-9 2.283153956254898e-8 8.782670653254268e-9 5295/5777/1437/5291/6776/84868/3558/3717/3563/2885/9846/3600/3635/5290/1439/50615/3718/3567/3932/6777/59067/3562/6464/6775/1438/3581/6774/6850/6772/8503/3636/6654/3716/5293/2185/6655/3561/3578/3568/3560/5296/3559/3601 43 Human_herpesvirus_1 R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 43/6371 44/10654 4.333465016121194e-9 2.283153956254898e-8 8.782670653254268e-9 834/79370/55367/472/1387/51499/8738/7159/637/27166/23368/332/64065/8797/7157/1121/604/63970/839/317/5875/55240/5366/84883/147923/843/94241/8626/7161/10397/8795/665/27113/9540/8793/835/58484/3486/355/8794/124446/5876/581 43 Human_herpesvirus_1 R-HSA-69231 Cyclin D associated events in G1 43/6371 44/10654 4.333465016121194e-9 2.283153956254898e-8 8.782670653254268e-9 8454/5925/1869/5753/1031/3717/5520/1032/28227/1030/5518/7314/5515/25/7027/5934/6714/5519/6502/595/896/6233/1163/1019/1029/4331/4067/1874/1870/7311/5516/894/902/1027/6500/7316/1875/1026/5933/1871/1021/1022/1028 43 Human_herpesvirus_1 R-HSA-69236 G1 Phase 43/6371 44/10654 4.333465016121194e-9 2.283153956254898e-8 8.782670653254268e-9 8454/5925/1869/5753/1031/3717/5520/1032/28227/1030/5518/7314/5515/25/7027/5934/6714/5519/6502/595/896/6233/1163/1019/1029/4331/4067/1874/1870/7311/5516/894/902/1027/6500/7316/1875/1026/5933/1871/1021/1022/1028 43 Human_herpesvirus_1 R-HSA-176187 Activation of ATR in response to replication stress 37/6371 37/10654 5.240888135730303e-9 2.740790388018958e-8 1.0543073208720609e-8 5982/4174/84515/4998/10926/990/84126/55388/6117/5001/6118/23594/63967/993/5985/4175/5984/5884/5810/4999/4172/5000/8318/4173/6119/3364/144715/1111/23595/5983/4176/1017/5883/8317/545/4171/995 37 Human_herpesvirus_1 R-HSA-6806003 Regulation of TP53 Expression and Degradation 37/6371 37/10654 5.240888135730303e-9 2.740790388018958e-8 1.0543073208720609e-8 11200/472/639/4194/8900/2475/5518/51230/7314/5515/6446/117584/890/983/5519/10000/900/7157/6233/7874/253260/5170/1029/80196/64223/1616/208/79109/7311/5516/1017/207/7316/55615/9099/5527/4193 37 Human_herpesvirus_1 R-HSA-167172 Transcription of the HIV genome 66/6371 73/10654 5.402411593427632e-9 2.8148358560589728e-8 1.0827905932059267e-8 6884/6875/6874/5431/5435/5433/2960/8732/2965/5439/6873/6881/2967/51616/11198/904/51497/2959/404672/5438/83860/2068/1025/6883/7936/6829/2957/25920/2963/5434/5436/6878/4331/8148/2966/2962/54457/8812/905/2071/6880/6908/6882/2961/5432/22916/6877/6917/5440/902/5430/6749/5441/7469/4686/6872/8731/6879/9150/2958/5437/6827/2968/138474/1022/8178 66 Human_herpesvirus_1 R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 69/6371 77/10654 6.066779291494168e-9 3.147345192269698e-8 1.2106978673111408e-8 1912/23165/7486/6045/80012/10274/348995/6613/57122/23511/54780/1911/6672/23279/23225/165918/57332/5371/8924/672/9972/6612/8021/6117/55746/79677/51564/51588/7518/10762/79902/9656/9883/84733/9063/6396/129401/7703/6015/8554/4928/5903/55706/7175/1029/8535/5885/641/4927/8243/142/1069/8086/7329/648/81929/5893/9631/79023/23636/10735/53371/6996/23137/9688/7341/9126/8480/7508 69 Human_herpesvirus_1 R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 47/6371 49/10654 6.085164571456286e-9 3.147345192269698e-8 1.2106978673111408e-8 9134/57060/2810/1869/6790/25904/1647/8900/55571/55835/57472/144455/85456/29883/1263/7027/7832/898/5934/890/10769/983/7157/5325/79733/1820/4869/4850/891/5111/246175/4848/23019/1874/1017/25946/4849/1027/9337/1026/5933/28984/2033/995/10498/581/3276 47 Human_herpesvirus_1 R-HSA-5387390 Hh mutants abrogate ligand secretion 55/6371 59/10654 6.425880664076538e-9 3.311439232728493e-8 1.2738203698284646e-8 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/51009/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/9861/5698/5692/5713/5710/5719/6233/27248/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 55 Human_herpesvirus_1 R-HSA-180585 Vif-mediated degradation of APOBEC3G 51/6371 54/10654 6.715746768716612e-9 3.4357371150100926e-8 1.3216343755369076e-8 5689/5682/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/60489/5706/5714/5688/5687/5708/5704/7311/5694/5684/8065/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_herpesvirus_1 R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 51/6371 54/10654 6.715746768716612e-9 3.4357371150100926e-8 1.3216343755369076e-8 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/2323/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/8471/2246/2251/5781/30849/5170/6464/2322/2263/3481/208/9365/6654/2549/3480/8822/8817/2254/152831/5289/26281/10818/2261/2255/27006/3479/5296 51 Human_herpesvirus_1 R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 42/6371 43/10654 7.105629726346041e-9 3.622075513935238e-8 1.3933136761522162e-8 2788/358/360/107/554/2782/2787/22841/5567/10681/112/5573/111/2792/2785/2783/2784/196883/115/2791/5568/359/113/5566/2786/5577/109/54331/5575/59345/51764/94235/114/108/8766/55970/2778/2793/5576/4645/551/2790 42 Human_herpesvirus_1 R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 58/6371 63/10654 8.676363093491224e-9 4.406843412953097e-8 1.6951924862709096e-8 55718/4790/5435/4792/3428/1387/84265/22954/1660/3551/7314/11035/8737/29110/81844/8517/6778/51428/5970/3661/6233/10622/661/11128/4791/9533/3665/5434/10623/23220/7098/9208/5591/7311/81030/51728/171568/10621/2547/1147/170506/5440/6737/1499/7520/147945/5441/51082/4615/7316/55703/27297/4793/5437/2033/11277/197358/148022 58 Human_herpesvirus_1 R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 36/6371 36/10654 8.784175252594195e-9 4.413969913403204e-8 1.697933856654282e-8 4893/71/5908/22866/5605/5037/2244/3690/408/5894/8826/4140/3845/3265/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/283455/3674/409/673/7450/60/7529/5595/5604/54518/10256/5906 36 Human_herpesvirus_1 R-HSA-6804757 Regulation of TP53 Degradation 36/6371 36/10654 8.784175252594195e-9 4.413969913403204e-8 1.697933856654282e-8 11200/472/4194/8900/2475/5518/51230/7314/5515/6446/117584/890/983/5519/10000/900/7157/6233/7874/253260/5170/1029/80196/64223/1616/208/79109/7311/5516/1017/207/7316/55615/9099/5527/4193 36 Human_herpesvirus_1 R-HSA-76046 RNA Polymerase III Transcription Initiation 36/6371 36/10654 8.784175252594195e-9 4.413969913403204e-8 1.697933856654282e-8 55718/2976/5435/9328/84265/55290/10302/9330/2972/2975/10622/7702/661/55814/11128/9533/5434/2971/10623/112495/9329/6621/6908/6619/51728/171568/10621/6618/5440/5451/6617/5441/51082/55703/27297/5437 36 Human_herpesvirus_1 R-HSA-112399 IRS-mediated signalling 46/6371 48/10654 9.8002256194937e-9 4.889723877994736e-8 1.880943433014227e-8 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/2323/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/2246/2251/5781/30849/5170/2322/2263/208/9365/6654/2549/8822/8817/2254/152831/5289/26281/10818/2261/2255/27006/5296 46 Human_herpesvirus_1 R-HSA-73893 DNA Damage Bypass 46/6371 48/10654 9.8002256194937e-9 4.889723877994736e-8 1.880943433014227e-8 56852/5982/9978/25898/57599/6117/10714/55666/7314/51514/6118/9636/11201/51455/5985/5984/6233/5424/8451/124739/54107/7706/8450/5425/5111/6119/83932/5427/1642/5429/9246/51426/7311/7318/5983/56655/57804/7320/7316/5426/9100/10459/7415/7398/5981/5980 46 Human_herpesvirus_1 R-HSA-4086400 PCP/CE pathway 80/6371 92/10654 9.95711267660185e-9 4.9505081335781034e-8 1.9043254785495013e-8 5689/5579/5682/5578/1212/5582/143471/5705/5709/5695/5881/5711/5683/5699/5702/57216/1855/163/5696/5691/4920/7314/5879/5718/161/5700/122706/5707/1856/8322/23198/7471/9861/5698/5880/5692/5713/5710/5719/6233/7474/1857/1213/1211/7855/1175/1173/144165/409/5706/160/5714/5688/5687/4919/5708/5704/7311/387/5694/57154/5684/5720/5690/5717/9491/10197/64750/7316/10213/5216/5715/5701/5685/5686/23513/5716/5693/5721/6259 80 Human_herpesvirus_1 R-HSA-169911 Regulation of Apoptosis 50/6371 53/10654 1.0655645324192233e-8 5.279217964126117e-8 2.0307711864388523e-8 5689/5682/4976/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Human_herpesvirus_1 R-HSA-3928662 EPHB-mediated forward signaling 41/6371 42/10654 1.164454911753688e-8 5.7489871867000256e-8 2.2114785957486312e-8 71/1947/2051/10094/2050/2047/2534/9475/1948/8976/6093/8997/3265/5879/1072/10093/5921/6453/2902/6714/7525/10109/2904/5747/7074/1949/2049/10092/4067/998/2048/10097/387/60/5058/3984/3985/6383/10552/10096/10095 41 Human_herpesvirus_1 R-HSA-111885 Opioid Signalling 79/6371 91/10654 1.4583890473222124e-8 7.175070853027749e-8 2.7600540928599364e-8 2788/5331/2770/817/5578/5582/5530/107/4988/2782/5499/5518/814/2773/5515/2787/818/5567/5594/10681/5142/112/5573/5528/111/5443/2792/5519/2785/2783/2784/5613/2771/5580/5153/196883/115/801/2791/805/3838/2781/5568/113/10645/5566/84254/23236/816/2786/5577/1020/109/5516/5533/815/5321/54331/5575/59345/5532/51764/94235/114/3708/108/2779/5173/55970/10768/346562/2793/5576/5534/1385/5144/808/5137/2790 79 Human_herpesvirus_1 R-HSA-6783783 Interleukin-10 signaling 45/6371 47/10654 1.5769272423267536e-8 7.731323840852001e-8 2.9740294482478253e-8 729230/7124/1437/3593/5743/941/3383/6349/3576/2920/1435/7133/3606/6347/3588/3569/3592/3587/6367/3976/3627/7076/7850/7297/3557/6351/6774/1440/3552/3716/1234/3586/3554/2208/3553/1230/2919/2357/6352/6348/6364/7132/942/6363/5724 45 Human_herpesvirus_1 R-HSA-388841 Costimulation by the CD28 family 63/6371 70/10654 1.8931713027529694e-8 9.222257569642997e-8 3.547550995926485e-8 5295/5777/5526/151888/941/3115/3113/3117/2534/2885/2475/5518/3127/5062/5879/5515/1326/5290/8764/57761/5528/9020/6714/5519/29126/10000/1445/916/7525/7409/3932/5781/1493/940/253260/3120/5170/3123/80380/3122/920/64223/8503/4067/29851/5063/5529/998/208/79109/5058/5516/9402/5525/3119/207/919/55615/915/917/942/5527/5296 63 Human_herpesvirus_1 R-HSA-74158 RNA Polymerase III Transcription 40/6371 41/10654 1.9071524152519513e-8 9.222257569642997e-8 3.547550995926485e-8 55718/2976/4774/5435/9328/84265/55290/10302/9330/2972/2975/10622/7702/661/55814/11128/9533/5434/2971/10623/112495/9329/6621/6908/6619/51728/171568/10621/4784/6618/5440/5451/6617/5441/51082/55703/27297/5437/4782/6741 40 Human_herpesvirus_1 R-HSA-749476 RNA Polymerase III Abortive And Retractive Initiation 40/6371 41/10654 1.9071524152519513e-8 9.222257569642997e-8 3.547550995926485e-8 55718/2976/4774/5435/9328/84265/55290/10302/9330/2972/2975/10622/7702/661/55814/11128/9533/5434/2971/10623/112495/9329/6621/6908/6619/51728/171568/10621/4784/6618/5440/5451/6617/5441/51082/55703/27297/5437/4782/6741 40 Human_herpesvirus_1 R-HSA-8853659 RET signaling 40/6371 41/10654 1.9071524152519513e-8 9.222257569642997e-8 3.547550995926485e-8 5295/2674/1796/5335/5291/5578/55816/2668/2885/8660/9846/5623/5290/5567/4902/6714/5598/64096/220164/9260/55715/5781/6464/5568/2675/2676/5566/8503/2886/6654/5293/2549/5909/10818/53358/5979/9048/5296/2887/9046 40 Human_herpesvirus_1 R-HSA-429914 Deadenylation-dependent mRNA decay 52/6371 56/10654 2.4624027188520885e-8 1.1849434370720946e-7 4.5581542681467186e-8 5393/80153/23404/26986/28960/219988/25904/1973/10767/55571/11340/57472/85456/29883/80349/51690/11157/1981/1977/23016/118460/9924/23644/5073/27258/4850/9652/255967/57819/246175/4848/23019/23658/1975/51010/56915/1974/167227/22894/1656/27257/4849/25804/10605/9337/55802/51013/196513/9775/54464/6499/54512 52 Human_herpesvirus_1 R-HSA-5654727 Negative regulation of FGFR2 signaling 34/6371 34/10654 2.4672335021189507e-8 1.1849434370720946e-7 4.5581542681467186e-8 2250/8569/2885/5518/2252/2253/7314/5515/8823/5594/8074/2249/6714/2248/2247/6233/2246/2251/5781/673/2263/7311/5595/5516/8822/10253/8817/2254/7316/26281/10818/867/2255/27006 34 Human_herpesvirus_1 R-HSA-5358346 Hedgehog ligand biogenesis 59/6371 65/10654 2.517549661019793e-8 1.2009392301891716e-7 4.6196857222127076e-8 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/6868/51009/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/9861/5698/5692/5713/5710/2262/5719/6233/27248/5706/84447/5714/5688/5687/5708/5704/7311/147111/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721/5034 59 Human_herpesvirus_1 R-HSA-9614085 FOXO-mediated transcription 59/6371 65/10654 2.517549661019793e-8 1.2009392301891716e-7 4.6196857222127076e-8 2308/857/2290/65018/57060/356/10971/7295/2810/84676/4089/1647/1387/4088/10628/4801/3630/56729/23411/2538/7534/847/5934/3484/5443/8850/10000/3066/604/5105/7532/4303/23410/4287/4800/901/9314/10370/2908/6794/4852/6648/4087/208/25942/7529/27113/2309/10018/4802/207/1027/6720/1649/114907/1026/2033/3065/10891 59 Human_herpesvirus_1 R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 48/6371 51/10654 2.6735843148342103e-8 1.2710777954700016e-7 4.8894896560498055e-8 5689/5682/143471/5705/5709/5695/5711/4946/5683/5699/5702/5696/5691/5718/1728/51582/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/5706/5714/5688/5687/5708/5704/5694/5684/5720/5690/51686/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 48 Human_herpesvirus_1 R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 99/6371 119/10654 2.820285836804165e-8 1.3363233562306983e-7 5.140471535821085e-8 84498/79718/9441/34/892/1543/5469/9612/11010/1387/6907/2101/84246/4801/2274/55588/10499/23054/9575/9572/85441/9282/23097/10062/7296/96764/51129/57761/5465/9915/2222/10025/6667/23309/336/3156/6604/9439/4199/123/2168/183/116519/9412/9969/405/133522/54797/55090/4899/1374/9440/6721/51/9862/23179/9442/406/19/335/4800/1024/9968/10001/23389/9971/9443/9477/25942/51586/400569/6095/6822/80306/8841/5468/29079/4802/4862/90390/6720/6837/9611/2874/81857/2033/9967/6256/51003/7376/10498/948/112950/196/4520/8202/8648/10891/219541 99 Human_herpesvirus_1 R-HSA-72766 Translation 218/6371 291/10654 2.9303718389880734e-8 1.3838411493816588e-7 5.3232595279628443e-8 6158/6138/5464/6227/6206/1965/6234/27335/6191/6128/6132/1917/84545/6129/1915/26284/80222/9255/6176/8668/6224/6146/6154/8662/26986/6202/64949/65003/10573/55052/6169/6175/6218/6728/64960/6173/64968/11222/6167/116832/118487/28977/6156/6143/1973/124995/28973/51116/6139/6745/64975/3921/51258/8665/10667/65005/84340/23478/6208/6170/92935/6203/51504/51253/10952/6147/8666/54534/6222/60488/64432/4528/8667/6727/7818/6184/79731/58477/2935/6134/6747/6731/55699/6155/55157/10240/6729/6231/6142/7458/8663/23521/23107/8894/65008/1981/85476/6185/6207/64978/1977/6726/6233/28957/51386/51373/6188/26589/10102/1978/64965/7284/200916/6122/1968/6230/8669/6194/2107/122704/6166/1938/1650/1983/6136/6125/1937/23395/10056/6232/6160/6748/51023/29927/1933/6193/6210/6229/6205/54148/28972/64976/140801/23438/79587/6235/51263/6181/740/8893/1975/7311/6223/25873/8664/6730/23708/9045/6187/6168/6157/6137/1974/55037/29074/51264/6144/10352/6182/9349/57505/4736/8891/29088/327/51121/65993/6159/56945/6217/1936/6152/79590/51065/6141/10480/6123/1967/6164/63931/8661/64963/9669/6209/1964/11224/6165/6130/8890/6204/64969/51081/6228/7965/6124/90480/2193/3646/6189/9789/6135/6201/6161/51649/54998/8892/6133/51021 218 Human_herpesvirus_1 R-HSA-5654741 Signaling by FGFR3 39/6371 40/10654 3.1216184036696424e-8 1.4643605269041645e-7 5.6329956156444684e-8 5295/4893/2250/5335/8569/2885/5518/2253/3845/3265/7314/5515/5290/8823/5594/8074/2249/6714/2247/6233/2246/5781/6464/673/6654/7311/2549/5595/5516/8822/10253/8817/10817/2254/7316/26281/10818/2261/867 39 Human_herpesvirus_1 R-HSA-5675221 Negative regulation of MAPK pathway 39/6371 40/10654 3.1216184036696424e-8 1.4643605269041645e-7 5.6329956156444684e-8 4893/1844/1850/1848/5526/1852/5605/5037/5894/1847/5518/4140/3845/3265/7314/5515/8844/1849/5594/5528/5519/80824/6233/1843/369/1846/11221/673/8315/5529/7311/5536/7529/5595/5516/5604/5525/7316/5527 39 Human_herpesvirus_1 R-HSA-2408522 Selenoamino acid metabolism 98/6371 118/10654 3.956581957867519e-8 1.8498985842744827e-7 7.116055386056605e-8 6158/6138/6227/6206/6234/6191/6128/6132/6129/9255/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/3176/6208/6170/7296/6203/6147/4143/191/6222/4837/2936/6134/60678/6155/6231/6142/9061/23521/6207/6233/51091/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/11185/51065/6141/6123/875/6164/6209/11224/6165/6130/6204/6228/51540/7965/6124/6189/6135/6201/6161/6133 98 Human_herpesvirus_1 R-HSA-4615885 SUMOylation of DNA replication proteins 43/6371 45/10654 4.0713358505498215e-8 1.89542850589515e-7 7.29119657851422e-8 23165/9212/348995/6613/57122/23511/6790/23279/23225/9972/6612/8021/55746/7150/51588/3619/7153/332/10762/79902/9883/7155/6396/129401/4928/5903/55706/7175/5111/4927/8086/7329/5905/81929/55143/9631/79023/23636/53371/9688/7341/10401/8480 43 Human_herpesvirus_1 R-HSA-113418 Formation of the Early Elongation Complex 33/6371 33/10654 4.1345041063435284e-8 1.89542850589515e-7 7.29119657851422e-8 5431/5435/5433/2965/5439/2967/51497/404672/5438/2068/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/7469/4686/9150/5437/6827/2968/1022 33 Human_herpesvirus_1 R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 33/6371 33/10654 4.1345041063435284e-8 1.89542850589515e-7 7.29119657851422e-8 5431/5435/5433/2965/5439/2967/51497/404672/5438/2068/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/7469/4686/9150/5437/6827/2968/1022 33 Human_herpesvirus_1 R-HSA-1839126 FGFR2 mutant receptor activation 33/6371 33/10654 4.1345041063435284e-8 1.89542850589515e-7 7.29119657851422e-8 2250/5431/5435/5433/5439/2252/2253/8823/8074/5438/2249/2248/2247/2246/2251/2963/5434/5436/2263/2962/5432/22916/8822/5440/5430/8817/5441/2254/4686/26281/5437/2255/27006 33 Human_herpesvirus_1 R-HSA-68962 Activation of the pre-replicative complex 33/6371 33/10654 4.1345041063435284e-8 1.89542850589515e-7 7.29119657851422e-8 5422/4174/84515/4998/10926/990/55388/6117/5001/5558/6118/23594/5557/4175/23649/4999/4172/5000/8318/54107/4173/51053/6119/5427/81620/29935/23595/4176/56655/1017/8317/5426/4171 33 Human_herpesvirus_1 R-HSA-9022692 Regulation of MECP2 expression and activity 33/6371 33/10654 4.1345041063435284e-8 1.89542850589515e-7 7.29119657851422e-8 2290/79718/817/9212/27327/28996/9612/6907/192669/4204/4343/814/818/3066/26523/801/805/3930/5566/816/25942/27161/815/8841/57690/192670/9611/2874/3064/3065/23112/1385/808 33 Human_herpesvirus_1 R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 47/6371 50/10654 4.227533572697986e-8 1.9318049853234813e-7 7.431126975003103e-8 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/2209/5706/5714/5688/5687/5708/9902/5704/5694/5684/5720/5690/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721/4360 47 Human_herpesvirus_1 R-HSA-1989781 PPARA activates gene expression 97/6371 117/10654 5.541354142899844e-8 2.523997435411155e-7 9.709129839512122e-8 84498/79718/9441/34/892/1543/5469/9612/11010/1387/6907/2101/84246/4801/2274/55588/10499/23054/9575/9572/85441/9282/23097/10062/7296/96764/51129/57761/5465/9915/2222/10025/6667/336/3156/6604/9439/4199/123/2168/183/116519/9412/9969/405/133522/54797/55090/4899/1374/9440/6721/51/9862/23179/9442/406/19/335/4800/1024/9968/10001/23389/9971/9443/9477/51586/400569/6095/6822/80306/8841/5468/29079/4802/4862/90390/6720/6837/9611/2874/81857/2033/9967/6256/51003/7376/10498/948/112950/196/4520/8202/8648/10891/219541 97 Human_herpesvirus_1 R-HSA-8848021 Signaling by PTK6 50/6371 54/10654 5.990437726763864e-8 2.7110570737790305e-7 1.0428697257119277e-7 4893/1796/5770/2909/9021/27043/3091/2064/5753/145957/9542/9564/3845/3265/5829/7314/5879/120892/1839/2065/2069/898/202559/5921/6421/595/6233/1019/10657/6774/2908/3084/10718/7311/2034/387/1956/63916/1017/685/207/55620/1027/10457/7316/1950/867/2066/1398/10656 50 Human_herpesvirus_1 R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 50/6371 54/10654 5.990437726763864e-8 2.7110570737790305e-7 1.0428697257119277e-7 4893/1796/5770/2909/9021/27043/3091/2064/5753/145957/9542/9564/3845/3265/5829/7314/5879/120892/1839/2065/2069/898/202559/5921/6421/595/6233/1019/10657/6774/2908/3084/10718/7311/2034/387/1956/63916/1017/685/207/55620/1027/10457/7316/1950/867/2066/1398/10656 50 Human_herpesvirus_1 R-HSA-983231 Factors involved in megakaryocyte development and platelet production 133/6371 168/10654 6.035496470700395e-8 2.7227223695300185e-7 1.0473570468745263e-7 9927/3443/57572/64837/11311/11127/51807/347688/3798/55619/10381/832/285643/3043/10112/64147/3717/7846/81027/11004/10749/2626/7465/81930/10603/5879/3445/25/113220/30846/5868/3797/23348/23186/5567/29127/3045/55605/3444/5573/91768/50808/3796/23414/124602/3451/55614/3448/89953/56992/10376/3066/7157/3439/55669/3835/147700/3833/161882/3452/9493/81704/3660/3446/9732/3831/84617/85440/9585/10019/10382/5568/830/3832/7277/3046/23303/2623/3659/5566/80005/26153/2627/1062/146909/347733/3440/90990/4602/998/7975/5577/23046/10383/24137/60/25942/84790/84643/3456/1020/22920/10362/7280/829/55582/11216/1017/23468/3441/2624/9371/8165/5575/23095/2625/3047/25970/3449/81928/3048/112714/3705/5576/547/3065/23028/3834/55083/3799/51317/10938/221458 133 Human_herpesvirus_1 R-HSA-109704 PI3K Cascade 42/6371 44/10654 6.532108864106775e-8 2.937368699400881e-7 1.1299256365669112e-7 5295/2250/5291/9965/2264/2885/8660/9846/2252/2253/2323/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/2246/2251/5781/30849/5170/2322/2263/208/9365/2549/8822/8817/2254/152831/5289/26281/10818/2261/2255/27006/5296 42 Human_herpesvirus_1 R-HSA-2871796 FCERI mediated MAPK activation 32/6371 32/10654 6.928017450320405e-8 3.085918182918742e-7 1.1870685719293805e-7 3725/4893/5335/2885/3845/3265/5062/5879/5601/5336/5594/4214/7410/7409/2353/6464/2205/3937/10451/2206/6850/4067/5602/6654/5058/6416/5595/9402/27040/5609/5599/2207 32 Human_herpesvirus_1 R-HSA-381042 PERK regulates gene expression 32/6371 32/10654 6.928017450320405e-8 3.085918182918742e-7 1.1870685719293805e-7 5393/1965/23404/3576/3309/4801/6347/11340/468/3484/1054/8894/9451/8570/23016/118460/1968/5073/1051/4800/22926/51010/56915/167227/22894/440/9709/4802/1649/51013/467/54512 32 Human_herpesvirus_1 R-HSA-5673000 RAF activation 32/6371 32/10654 6.928017450320405e-8 3.085918182918742e-7 1.1870685719293805e-7 4893/5526/817/5605/3717/4296/5894/5518/4140/3845/3265/5515/818/8844/5528/6714/5519/369/801/805/673/8315/5529/816/7529/5516/815/5604/5525/5527/808/5245 32 Human_herpesvirus_1 R-HSA-1236394 Signaling by ERBB4 53/6371 58/10654 7.60416427423203e-8 3.376440237489191e-7 1.2988244837814392e-7 5295/4893/2670/51741/23385/6776/4734/10413/145957/83737/6868/9542/2885/3845/2561/3265/2560/7314/6387/1839/5290/55879/6678/2065/2069/23118/348/11059/6714/2099/1447/2567/2566/3925/6233/5663/2554/6464/5241/3084/6654/10718/7311/1956/685/2562/7316/1950/9611/2066/6285/1742/11033 53 Human_herpesvirus_1 R-HSA-1852241 Organelle biogenesis and maintenance 220/6371 296/10654 7.710822089149016e-8 3.4130660783317893e-7 1.3129134459663067e-7 55763/5563/57728/79738/79867/55735/79718/7531/11190/203068/11127/54801/51807/85302/347688/79441/53632/10381/5116/3313/5048/10576/5469/10989/22832/60412/192668/8655/83658/6010/89891/9702/132320/1432/1387/25813/7846/7840/6907/2101/11064/84902/81027/84808/2847/10499/23054/5518/1386/55835/9572/85441/3054/23332/7019/93323/814/96764/79659/3797/10575/1454/112752/9321/23408/51422/10013/54806/5465/91147/7978/54927/983/64784/79959/5310/4208/6604/8729/10376/10540/11336/117177/57545/26005/54930/54820/23322/6742/378/56623/5600/1453/6300/801/9793/4218/133522/140735/64216/57576/805/6102/84617/4899/5442/11258/22981/8636/54903/80776/79135/3842/3418/7532/55125/10382/23082/6753/79809/23410/121441/7277/55112/26146/8834/9814/4209/23354/2553/146057/9738/1639/55722/4957/5566/5571/2551/7283/4580/347733/22919/27077/22994/4867/5311/6648/1069/10651/5577/10383/5347/403/84790/22948/80184/22897/5564/51106/23373/5565/22920/5108/261734/2746/57787/7280/10806/9657/1778/55770/23265/139322/115106/10694/22995/55559/8841/9371/10142/10640/51134/95681/57539/200186/79989/112714/7203/1781/80321/8766/9611/23409/79598/54205/149371/10121/347240/84131/6950/55212/3320/79600/10733/6256/4751/10498/80254/1385/200894/26123/808/54536/9662/55142/8648/8481/51259/55755/10891 220 Human_herpesvirus_1 R-HSA-5655302 Signaling by FGFR1 in disease 37/6371 38/10654 8.346720289105844e-8 3.6829903275679537e-7 1.4167459438087552e-7 5295/4893/11052/2250/5335/9530/613/6776/11064/2885/9846/2253/3845/3265/7750/8805/26127/5290/8074/2260/2249/399687/2247/2246/2251/6777/1523/9208/6774/6772/6654/11160/2549/8822/2254/26281/10818 37 Human_herpesvirus_1 R-HSA-109606 Intrinsic Pathway for Apoptosis 49/6371 53/10654 9.323802547801536e-8 4.1013112764784324e-7 1.577662605235479e-7 7531/55075/10971/7533/2810/1869/8655/836/90427/840/7159/637/578/23368/7027/5594/841/7534/4836/598/10000/708/3002/7157/331/57099/317/140735/1029/572/7532/6774/5366/56616/8626/208/7161/7529/5595/5533/27113/596/10018/842/207/54205/5534/581/5599 49 Human_herpesvirus_1 R-HSA-391251 Protein folding 85/6371 101/10654 9.451291813107472e-8 4.1444795155614133e-7 1.5942682496121139e-7 2788/9134/1459/2770/51807/10528/1460/10381/10576/1457/7846/7411/2782/81027/10574/6468/10564/54461/10693/8877/2773/5201/2787/5204/10575/10681/898/10517/2792/10471/26985/2785/10376/2783/26190/2784/10238/7157/2771/83752/2791/6904/5202/26224/84617/2629/2781/8237/10382/7277/63971/6774/26272/26270/347733/55135/5082/2786/10383/60/84790/22948/7280/84261/10694/8841/54331/22803/59345/5203/51764/94235/2779/112714/7203/908/55970/346562/1155/2793/6950/55294/6499/26234/2790 85 Human_herpesvirus_1 R-HSA-5628897 TP53 Regulates Metabolic Genes 74/6371 86/10654 9.587099448431673e-8 4.191016848664248e-7 1.6121698925829374e-7 5563/7531/10971/9997/27327/7295/7533/2810/53632/7001/10325/192669/2475/10670/4513/4343/64121/7296/9377/2936/51422/7249/27244/7534/1351/2821/10000/2877/54541/7157/50484/9167/26523/2744/57521/28956/83667/389541/7532/1345/58528/84987/64223/5571/10128/25824/6009/8626/208/55004/5562/1340/4697/5564/5565/7248/7529/27161/27165/207/57690/192670/153129/2539/54205/143686/1350/8649/5728/23112/10542/1349/1327/5052 74 Human_herpesvirus_1 R-HSA-1433557 Signaling by SCF-KIT 41/6371 43/10654 1.0469239663694834e-7 4.5436108797726556e-7 1.7478032011053306e-7 5295/5777/4893/5578/6776/3717/2534/2885/9846/3845/3265/10603/5879/5290/3815/9306/6714/7525/7409/3932/6777/5781/10019/2241/4318/6774/6772/8651/8503/4067/1111/2886/6654/7006/9402/867/4254/5296/10076/2887/2242 41 Human_herpesvirus_1 R-HSA-168325 Viral Messenger RNA Synthesis 41/6371 43/10654 1.0469239663694834e-7 4.5436108797726556e-7 1.7478032011053306e-7 23165/348995/57122/5431/23511/5435/5433/23279/23225/5439/9972/8021/55746/5438/10762/79902/9883/6396/129401/4928/2963/5434/5903/55706/7175/5436/4927/2962/8086/5432/81929/5440/9631/5430/79023/5441/23636/53371/9688/5437/8480 41 Human_herpesvirus_1 R-HSA-74752 Signaling by Insulin receptor 68/6371 78/10654 1.0490206422138002e-7 4.5436108797726556e-7 1.7478032011053306e-7 5295/3643/4893/2250/5291/535/50617/10312/9965/2264/3630/2885/8660/9846/2252/2253/3845/3265/2323/54106/51606/5290/3667/8823/526/537/9550/9114/5594/8074/57761/2260/2249/2248/2247/529/2246/2251/523/528/5781/30849/5170/6464/2322/527/2263/208/9365/6654/2549/5595/8822/8817/2254/152831/5289/26281/10818/23545/2261/245972/2255/27006/5296/51382/9296/2887 68 Human_herpesvirus_1 R-HSA-418597 G alpha (z) signalling events 45/6371 48/10654 1.0530497447987401e-7 4.547113882739514e-7 1.7491507108197325e-7 2788/5579/2770/5578/5582/5583/107/2782/6004/2773/2787/10681/112/111/2792/5588/2785/2783/2784/2771/5580/196883/115/5999/2791/2781/150/113/8601/2786/109/151/54331/59345/51764/94235/114/108/55970/2778/346562/152/2793/5581/2790 45 Human_herpesvirus_1 R-HSA-182971 EGFR downregulation 31/6371 31/10654 1.1608253844598355e-7 4.966925584416023e-7 1.9106408241826956e-7 374/7039/6456/30011/2885/8874/10252/7314/1839/8027/2060/2069/9146/6455/6233/29924/255324/5782/5796/998/7311/1956/10253/685/58513/7316/1950/867/5774/10254/6457 31 Human_herpesvirus_1 R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 31/6371 31/10654 1.1608253844598355e-7 4.966925584416023e-7 1.9106408241826956e-7 3725/9252/1848/1432/6196/5518/1386/6197/51231/5515/5601/1849/5594/5528/9261/5519/5598/4208/6195/2353/5600/1846/5602/5595/5516/1845/4205/466/2002/1385/5599 31 Human_herpesvirus_1 R-HSA-5654733 Negative regulation of FGFR4 signaling 31/6371 31/10654 1.1608253844598355e-7 4.966925584416023e-7 1.9106408241826956e-7 8569/9965/2264/2885/5518/2253/7314/5515/8823/5594/8074/2249/6714/2247/6233/2246/2251/5781/673/7311/5595/5516/8822/10253/8817/2254/7316/152831/26281/10818/867 31 Human_herpesvirus_1 R-HSA-5358351 Signaling by Hedgehog 119/6371 149/10654 1.2125613466207416e-7 5.17261819162685e-7 1.9897651609359287e-7 8454/5689/57728/5682/11127/22873/1452/51684/143471/10381/5705/8452/5709/9978/5695/107/5711/7846/5683/408/5699/6400/5702/81027/83737/6868/51009/6469/5696/5691/7314/5718/8945/79659/5700/122706/5707/5567/10956/23198/112/5573/2737/5727/8650/111/9861/8405/2932/5698/5692/5713/10376/5710/2262/5719/6233/27248/23322/196883/115/84617/54903/91653/10382/23288/79809/5568/409/79577/7277/5706/113/84447/5714/5566/2736/5688/5687/5708/347733/5577/5704/7311/147111/10383/84790/5694/7280/109/57154/5684/5720/2735/5575/5690/5717/9491/6500/57539/114/7289/10197/108/64750/7316/10213/2778/7415/5715/5701/5576/5685/5686/5716/8481/5693/5721/5034 119 Human_herpesvirus_1 R-HSA-5685938 HDR through Single Strand Annealing (SSA) 36/6371 37/10654 1.363425114596957e-7 5.798663439189467e-7 2.2305876954090994e-7 83990/9156/1763/7486/5982/472/4683/84126/2067/672/6117/83695/6118/25/5888/116028/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/5983/5893/5883/10111/545/2072/5932/7156 36 Human_herpesvirus_1 R-HSA-3371453 Regulation of HSF1-mediated heat shock response 61/6371 69/10654 1.55261470144621e-7 6.583459334660806e-7 2.5324772749999824e-7 23165/573/7531/9530/348995/472/57122/3313/23511/3305/23279/23225/3309/9531/3306/9972/23411/8021/6117/3312/55746/51182/3303/6118/5594/3308/10049/3337/10762/9261/79902/9883/2932/6396/129401/3297/4928/5903/55706/7175/4927/6119/57805/3310/7266/8086/3304/5595/81929/9631/545/79023/23636/10808/53371/9532/9688/6767/22824/9529/8480 61 Human_herpesvirus_1 R-HSA-1980143 Signaling by NOTCH1 64/6371 73/10654 1.568598622112337e-7 6.631321121025808e-7 2.550888399022899e-7 8454/79718/892/113878/182/3091/23385/9978/9759/9612/4609/22938/1387/6907/408/83737/6868/9794/57534/388585/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/7091/8650/1272/102/8850/3066/6233/5663/7090/142678/23220/409/10046/1024/10014/26508/9148/7088/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/1840/54567/3516 64 Human_herpesvirus_1 R-HSA-73762 RNA Polymerase I Transcription Initiation 44/6371 47/10654 1.6587282730147554e-7 6.991415885065179e-7 2.689407034958724e-7 2074/9112/5435/5928/2965/1107/2967/2648/30834/404672/8850/57459/2068/3066/9533/5434/9015/79101/9219/5931/7270/4331/9013/1108/2966/54815/2071/57504/6908/53615/5440/902/9014/25885/54700/5441/51082/7343/5437/3065/2968/84172/1022/10919 44 Human_herpesvirus_1 R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 40/6371 42/10654 1.6761102485217456e-7 7.02275273267865e-7 2.701461465679278e-7 23165/348995/57122/23511/81608/23279/23225/9972/8021/55746/53981/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/7884/4927/10898/10482/51692/8086/22916/81929/9631/29894/79023/23636/4686/8189/53371/9688/10189/8480/55339 40 Human_herpesvirus_1 R-HSA-168253 Host Interactions with Influenza Factors 40/6371 42/10654 1.6761102485217456e-7 7.02275273267865e-7 2.701461465679278e-7 3839/23165/348995/57122/23511/23279/23225/3836/9972/8021/7040/55746/402569/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/3841/293/4927/10898/3840/8086/3837/81929/9631/79023/23636/53371/9688/8480 40 Human_herpesvirus_1 R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 30/6371 30/10654 1.9448996821481288e-7 8.053367598806915e-7 3.0979108997945194e-7 56852/5982/9978/57599/6117/10714/7314/51514/6118/5985/5984/6233/5424/8451/54107/8450/5425/5111/6119/5427/1642/7311/5983/56655/57804/7320/7316/5426/7398/5981 30 Human_herpesvirus_1 R-HSA-180786 Extension of Telomeres 30/6371 30/10654 1.9448996821481288e-7 8.053367598806915e-7 3.0979108997945194e-7 2237/1763/5982/5422/6117/10714/5558/6118/3978/5557/5985/5984/23649/8607/5424/55651/54107/5425/5111/6119/5427/55135/5983/56655/7015/57804/10856/5426/1736/5981 30 Human_herpesvirus_1 R-HSA-5654696 Downstream signaling of activated FGFR2 30/6371 30/10654 1.9448996821481288e-7 8.053367598806915e-7 3.0979108997945194e-7 5295/4893/2250/5335/2885/2252/2253/3845/3265/5290/8823/8074/2249/2248/2247/2246/2251/5781/6464/2263/6654/2549/8822/8817/10817/2254/26281/10818/2255/27006 30 Human_herpesvirus_1 R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 30/6371 30/10654 1.9448996821481288e-7 8.053367598806915e-7 3.0979108997945194e-7 11065/7321/65264/8239/55236/3093/7347/7328/7332/7314/90268/10477/92912/29089/7324/6233/7874/7326/7317/8078/7327/7311/997/7319/7320/7316/54926/7322/55284/27338 30 Human_herpesvirus_1 R-HSA-202733 Cell surface interactions at the vascular wall 110/6371 137/10654 2.1591889733313106e-7 8.914546287555001e-7 3.429182856998942e-7 5295/3675/5777/4893/857/5335/6385/960/5291/7056/2995/5175/9463/3688/6404/972/2534/3690/2885/51206/4072/5676/6382/5673/7040/3845/4282/3265/3655/6693/3635/5290/5680/6401/4680/4312/50848/3683/6714/965/8797/4973/2335/23539/2734/5671/5478/7525/3685/3932/634/9672/5781/7102/5672/2147/6464/3684/7010/1048/2888/10461/83700/3678/1277/338/5670/8140/6403/4067/140885/5624/2886/6402/6654/4099/23657/285/3897/8795/5669/3676/2817/8793/5675/1525/2993/6383/5196/2621/83953/54210/682/1088/57126/23759/5678/6520/440533/5296/3687/1278/481/3689/961/2207/5627/6566/284/9046 110 Human_herpesvirus_1 R-HSA-168638 NOD1/2 Signaling Pathway 35/6371 36/10654 2.225490764279402e-7 9.143887827684367e-7 3.517404293339148e-7 834/1432/5603/83737/3654/7334/1540/3551/7314/257397/8767/23118/841/8517/7128/837/10454/6233/5600/6300/5608/387522/330/64127/3656/7189/7311/1147/6885/842/10392/835/7316/7335/329 35 Human_herpesvirus_1 R-HSA-4608870 Asymmetric localization of PCP proteins 57/6371 64/10654 2.2276893857814603e-7 9.143887827684367e-7 3.517404293339148e-7 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/57216/5696/5691/7314/5718/5700/122706/5707/1856/8322/23198/9861/5698/5692/5713/5710/5719/6233/7474/7855/144165/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/23513/5716/5693/5721 57 Human_herpesvirus_1 R-HSA-3928665 EPH-ephrin mediated repulsion of cells 47/6371 51/10654 2.2486437352597154e-7 9.203144794744111e-7 3.540198832628568e-7 71/2042/1947/1212/23385/2051/2045/2050/285220/2047/2534/1948/163/284656/1759/5879/161/2046/4313/2041/102/6714/1943/2043/7525/1942/7410/1213/1211/1175/5663/1173/7074/1949/1945/10451/4318/160/2049/8218/4067/2044/2048/60/1946/1944/1969 47 Human_herpesvirus_1 R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 85/6371 102/10654 2.3457986981236045e-7 9.573028213151821e-7 3.682482896963127e-7 8454/8792/7124/5689/5682/356/9039/143471/5705/10673/5709/5695/7292/7133/5711/5683/5699/5702/60401/8740/944/7187/958/5696/5691/939/7314/5718/8945/5700/122706/5707/23198/8764/9020/8741/1896/9861/5698/5692/5713/5710/8718/9040/5719/6233/8742/4791/959/8600/330/5706/5714/5688/5687/608/5708/5704/7311/5971/115650/5694/1147/5684/5720/7186/5690/5717/9491/6500/10197/7316/10213/5715/7132/5701/329/23291/5685/5686/4049/5716/8784/5693/5721 85 Human_herpesvirus_1 R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 39/6371 41/10654 2.6803705177814297e-7 1.090686792826334e-6 4.195574661535622e-7 23165/348995/57122/23511/81608/23279/23225/9972/8021/55746/53981/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10898/10482/51692/8086/22916/81929/9631/29894/79023/23636/4686/8189/53371/9688/10189/8480/55339 39 Human_herpesvirus_1 R-HSA-1638091 Heparan sulfate/heparin (HS-GAG) metabolism 50/6371 55/10654 2.746158394420585e-7 1.1142458772763982e-6 4.286200034848826e-7 10675/126792/6385/9653/3340/9956/64579/27087/135152/6448/1463/26035/221914/9348/64711/6382/90161/2720/63827/633/8509/375790/9957/9955/2262/11285/9672/2990/2132/64132/222537/266722/9953/138050/64131/1464/2239/60495/2719/26229/2131/9951/2817/3339/1634/6383/1462/9394/10855/10082 50 Human_herpesvirus_1 R-HSA-380108 Chemokine receptors bind chemokines 53/6371 59/10654 3.113256095766559e-7 1.2595752456224587e-6 4.845242483533538e-7 729230/7852/1237/6349/3576/6360/2920/2921/1236/6370/58191/1524/643/2833/6347/6387/10663/3579/6367/2826/6376/6354/3627/6346/9034/51554/2829/1233/6366/6373/6357/6361/10803/6351/3577/10563/10850/5473/4283/6356/56477/1234/57007/6374/1230/2919/5196/6352/6348/6364/6372/6363/1232 53 Human_herpesvirus_1 R-HSA-186763 Downstream signal transduction 29/6371 29/10654 3.2583663076038965e-7 1.3070492120274722e-6 5.0278618861352e-7 5295/4893/5335/5291/6776/2885/8440/9564/3845/3265/1399/5290/5921/6778/6714/5154/6777/5781/6774/6772/2889/5159/2886/6654/4690/1398/5155/5296/5156 29 Human_herpesvirus_1 R-HSA-5654732 Negative regulation of FGFR3 signaling 29/6371 29/10654 3.2583663076038965e-7 1.3070492120274722e-6 5.0278618861352e-7 2250/8569/2885/5518/2253/7314/5515/8823/5594/8074/2249/6714/2247/6233/2246/5781/673/7311/5595/5516/8822/10253/8817/2254/7316/26281/10818/2261/867 29 Human_herpesvirus_1 R-HSA-72086 mRNA Capping 29/6371 29/10654 3.2583663076038965e-7 1.3070492120274722e-6 5.0278618861352e-7 5431/5435/5433/8732/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/4686/8731/5437/2968/1022 29 Human_herpesvirus_1 R-HSA-73894 DNA Repair 243/6371 334/10654 3.501842718778688e-7 1.4007370875114753e-6 5.38825359442315e-7 2237/4436/221120/83990/151987/4350/9156/2074/1763/7486/27343/4913/56852/10445/5982/11200/472/6613/27434/7507/80198/3981/5431/5435/9978/5433/85015/26277/10980/64421/4683/57654/2965/25898/165918/84126/54890/5439/10987/8900/8924/57599/2067/672/2967/6612/121642/6117/7334/10973/10714/55666/54386/348654/91603/83695/4437/55183/7314/51514/7014/6118/2176/25/5888/322/328/83444/51588/7518/51720/63967/404672/9557/5531/9636/3150/23583/86/5438/3978/11201/116028/2070/890/9031/1643/7517/9656/51455/29844/2177/5985/10920/29089/2068/7157/5984/4595/4255/6233/7158/6047/93973/55247/8607/7874/5884/5810/5424/5886/8451/8554/10450/8467/80010/124739/3838/5434/5436/2956/7515/54107/7013/4292/7706/51567/580/11073/5591/8450/4331/5425/641/5111/2966/6119/83932/3364/22976/10524/5427/144715/1161/55775/1642/5429/142/125476/1111/2071/55215/1069/7329/9246/79728/51426/2873/7311/7318/4968/23030/3980/60/5536/8533/5983/2175/10038/2547/79840/5432/51138/7528/56655/9318/11284/51750/1017/25913/6917/5440/5893/2178/902/5883/27339/5430/10111/57804/7320/7520/675/51548/545/5441/7336/2072/29086/54778/7316/6996/64708/8314/5426/9100/10635/10459/7415/5395/283899/7341/5437/51008/79913/10401/54617/65057/2033/8914/7398/64858/2968/5932/8930/2138/9025/2189/79184/56949/7156/5887/9716/2073/5599/5981/57461/1022/2139/8178/50813/5980/7508 243 Human_herpesvirus_1 R-HSA-168276 NS1 Mediated Effects on Host Pathways 38/6371 40/10654 4.2812391973979357e-7 1.7076581205440354e-6 6.568895111083363e-7 3839/23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/402569/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/3841/4927/10898/3840/8086/3837/81929/9631/79023/23636/53371/9688/8480 38 Human_herpesvirus_1 R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 52/6371 58/10654 4.7057699842781896e-7 1.8508488071868534e-6 7.119710634474552e-7 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/57534/388585/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/102/8850/3066/6233/5663/142678/10046/1024/10014/26508/9148/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/54567/3516 52 Human_herpesvirus_1 R-HSA-2644603 Signaling by NOTCH1 in Cancer 52/6371 58/10654 4.7057699842781896e-7 1.8508488071868534e-6 7.119710634474552e-7 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/57534/388585/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/102/8850/3066/6233/5663/142678/10046/1024/10014/26508/9148/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/54567/3516 52 Human_herpesvirus_1 R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 52/6371 58/10654 4.7057699842781896e-7 1.8508488071868534e-6 7.119710634474552e-7 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/57534/388585/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/102/8850/3066/6233/5663/142678/10046/1024/10014/26508/9148/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/54567/3516 52 Human_herpesvirus_1 R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 52/6371 58/10654 4.7057699842781896e-7 1.8508488071868534e-6 7.119710634474552e-7 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/57534/388585/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/102/8850/3066/6233/5663/142678/10046/1024/10014/26508/9148/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/54567/3516 52 Human_herpesvirus_1 R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 52/6371 58/10654 4.7057699842781896e-7 1.8508488071868534e-6 7.119710634474552e-7 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/57534/388585/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/102/8850/3066/6233/5663/142678/10046/1024/10014/26508/9148/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/54567/3516 52 Human_herpesvirus_1 R-HSA-350054 Notch-HLH transcription pathway 28/6371 28/10654 5.458521265110991e-7 2.123259511387526e-6 8.167600327090826e-7 79718/9759/9612/22938/1387/6907/4853/9794/79885/2648/9734/55869/51564/55534/84441/10013/83933/4854/8850/3066/10046/10014/4855/4851/8841/9611/3065/3516 28 Human_herpesvirus_1 R-HSA-75067 Processing of Capped Intronless Pre-mRNA 28/6371 28/10654 5.458521265110991e-7 2.123259511387526e-6 8.167600327090826e-7 51585/81608/1477/53981/134353/11051/8106/1478/23283/6636/10914/6635/7884/84967/6637/10898/51692/22916/1479/25888/79869/29894/4686/8189/10978/6634/55339/6628 28 Human_herpesvirus_1 R-HSA-76061 RNA Polymerase III Transcription Initiation From Type 1 Promoter 28/6371 28/10654 5.458521265110991e-7 2.123259511387526e-6 8.167600327090826e-7 55718/2976/5435/9328/84265/9330/2972/2975/10622/661/55814/11128/9533/5434/2971/10623/112495/9329/6908/51728/171568/10621/5440/5441/51082/55703/27297/5437 28 Human_herpesvirus_1 R-HSA-76071 RNA Polymerase III Transcription Initiation From Type 3 Promoter 28/6371 28/10654 5.458521265110991e-7 2.123259511387526e-6 8.167600327090826e-7 55718/5435/84265/55290/10302/10622/7702/661/55814/11128/9533/5434/10623/6621/6908/6619/51728/171568/10621/6618/5440/5451/6617/5441/51082/55703/27297/5437 28 Human_herpesvirus_1 R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 33/6371 34/10654 5.915443404575491e-7 2.2946720019946685e-6 8.826977434242203e-7 7321/9140/9474/3093/64135/83737/7187/1540/7314/29110/9636/8887/7323/23586/7128/3661/51191/6233/55593/84282/54476/7706/9246/7311/7318/5094/9641/57506/84166/7316/7322/54941/5300 33 Human_herpesvirus_1 R-HSA-5689880 Ub-specific processing proteases 166/6371 220/10654 5.938412080027383e-7 2.2972706457530586e-6 8.83697370813015e-7 5689/645836/5682/79594/7419/10474/7375/9817/91833/6478/3091/143471/100287513/5705/11274/55031/8239/5709/5695/4792/9986/11047/4609/392188/4194/4089/100287144/5711/4088/5683/408/64135/5699/8724/8312/100287327/5702/8900/8975/57599/377630/6881/51616/728386/1540/100287404/5696/5691/7314/5718/6314/90865/2648/5700/122706/5707/8737/55611/100287364/57646/23198/63967/9101/8517/993/890/7417/4092/1643/9861/23586/81847/64426/100287441/7046/6502/5698/9146/5692/5713/5710/10454/7157/10869/9958/8313/5719/6233/100287478/9804/23770/8607/7874/100287178/100287238/10600/23326/51651/8237/4303/409/330/5706/27005/7416/25862/9738/8658/84132/5714/79589/55288/27430/5688/9097/5687/8078/5708/4087/63891/84749/7189/5704/7311/367/29761/5694/9960/23358/23032/5684/8295/5720/7186/6885/991/5690/2625/5717/9491/4086/1080/57695/10197/64750/7316/10213/8678/9100/5715/3416/5701/329/9099/5685/5686/5728/10868/5716/9736/5693/154/10254/5721/100287205/4193 166 Human_herpesvirus_1 R-HSA-191859 snRNP Assembly 48/6371 53/10654 6.409252065386595e-7 2.4659029744757144e-6 9.485656290662507e-7 23165/6633/6606/8487/25929/348995/57122/23511/23279/23225/79084/9972/8021/55746/96764/10762/79902/9883/6636/10419/6396/129401/50628/4928/6635/5903/6632/55706/7175/6637/4927/51808/8086/79833/22916/81929/11218/9631/79023/23636/10073/4686/53371/9688/1207/6634/8480/6628 48 Human_herpesvirus_1 R-HSA-194441 Metabolism of non-coding RNA 48/6371 53/10654 6.409252065386595e-7 2.4659029744757144e-6 9.485656290662507e-7 23165/6633/6606/8487/25929/348995/57122/23511/23279/23225/79084/9972/8021/55746/96764/10762/79902/9883/6636/10419/6396/129401/50628/4928/6635/5903/6632/55706/7175/6637/4927/51808/8086/79833/22916/81929/11218/9631/79023/23636/10073/4686/53371/9688/1207/6634/8480/6628 48 Human_herpesvirus_1 R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 41/6371 44/10654 6.42766939247317e-7 2.4662687995032926e-6 9.487063519783056e-7 892/7321/8239/9612/4609/4089/22938/23327/4088/1030/904/7314/5054/7027/6497/51592/7323/6667/4092/7050/5494/6233/1025/4221/3726/1024/60436/8812/1874/142/905/4087/7311/64750/54778/7316/1875/9611/5933/3065/6498 41 Human_herpesvirus_1 R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 37/6371 39/10654 6.829713961713887e-7 2.613429841176154e-6 1.0053151916258355e-6 5982/25898/6117/10714/55666/7314/6118/9636/11201/51455/5985/5984/6233/5424/124739/54107/7706/5425/5111/6119/83932/5427/5429/9246/51426/7311/7318/5983/56655/57804/7316/5426/9100/10459/7415/5981/5980 37 Human_herpesvirus_1 R-HSA-948021 Transport to the Golgi and subsequent modification 142/6371 185/10654 6.921625090530551e-7 2.6414417913051727e-6 1.0160906249541294e-6 6811/23256/374/6711/11014/126003/2153/51807/286/10484/7039/347688/5861/10381/1780/9570/8655/84516/832/3998/55738/7846/1081/51226/9382/375056/9632/3630/81027/6709/79090/10652/54732/51164/9486/58485/10342/4253/2801/377/10466/2517/22872/1315/8615/55014/11316/91949/8729/23423/10376/1314/10540/51332/83696/27095/6399/7109/378/6396/26286/1453/26958/140735/10959/84364/22820/84617/11258/6712/2890/1783/8703/10382/10802/93661/55860/2157/830/7277/10671/9554/966/11196/1639/149111/10282/6710/8775/81876/11015/347733/51143/51693/23243/5537/9871/10383/84790/10945/1075/7280/829/1778/9919/10113/51399/11070/25839/55291/51014/122553/26984/83548/63908/112714/1604/1781/57731/1522/10121/2804/9527/57511/22870/64377/5265/8774/10972/381/6708/4905/11320/2683/9276/287/375/64689/288/10427/22818/372 142 Human_herpesvirus_1 R-HSA-170834 Signaling by TGF-beta Receptor Complex 63/6371 73/10654 7.022253727430506e-7 2.672620556100236e-6 1.0280842455253627e-6 892/7321/4738/8239/9612/4609/4089/22938/23327/4088/5499/1030/9110/7040/904/7314/5054/7027/6497/51592/50848/7323/6667/4092/11171/7050/7046/5494/2280/9958/9040/6233/7514/1025/57530/5500/4221/5590/3726/5501/1024/60436/8812/1874/142/905/4087/7048/7311/387/57154/51377/10273/64750/54778/7316/1875/9611/5933/867/3065/6498/56288 63 Human_herpesvirus_1 R-HSA-447115 Interleukin-12 family signaling 51/6371 57/10654 7.099545662090179e-7 2.6947737835675628e-6 1.036605988013167e-6 3593/5908/3313/6175/3936/5898/3717/3181/4001/3594/4282/5062/3572/10148/1072/3592/6627/9049/27250/9987/3185/149233/3458/5478/302/552900/51561/7297/6775/9446/3595/821/4478/6774/6772/998/6648/3716/2939/6888/246778/3586/829/6647/6950/9466/4507/6845/375/5721/5034 51 Human_herpesvirus_1 R-HSA-112382 Formation of RNA Pol II elongation complex 54/6371 61/10654 7.460735327040273e-7 2.8167268133103917e-6 1.0835179928941122e-6 5431/5435/5433/2965/5439/2967/11198/904/51497/4300/80349/404672/5438/2068/1025/23168/55677/7936/6829/123169/25920/85403/2963/5434/5436/9646/79577/4331/2966/2962/4298/8812/905/2071/27125/5432/22916/55840/6917/5440/902/6830/5430/6749/5441/7469/4686/9150/54623/5437/6827/2968/1022/8178 54 Human_herpesvirus_1 R-HSA-75955 RNA Polymerase II Transcription Elongation 54/6371 61/10654 7.460735327040273e-7 2.8167268133103917e-6 1.0835179928941122e-6 5431/5435/5433/2965/5439/2967/11198/904/51497/4300/80349/404672/5438/2068/1025/23168/55677/7936/6829/123169/25920/85403/2963/5434/5436/9646/79577/4331/2966/2962/4298/8812/905/2071/27125/5432/22916/55840/6917/5440/902/6830/5430/6749/5441/7469/4686/9150/54623/5437/6827/2968/1022/8178 54 Human_herpesvirus_1 R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 57/6371 65/10654 7.530686490714159e-7 2.8355544866369047e-6 1.0907604853918615e-6 3725/4436/472/5431/5435/5433/2965/5439/672/2967/1386/11198/904/51497/2176/404672/5438/1643/9656/2177/2068/7157/1025/2353/7936/6829/25920/2963/5434/5436/4292/4331/2966/2962/8812/905/1111/2071/55215/5432/6917/5440/8621/902/5430/6749/545/5441/7469/5395/9150/5437/51755/6827/2968/1022/8178 57 Human_herpesvirus_1 R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 27/6371 27/10654 9.143711457177548e-7 3.3886930649697368e-6 1.3035378123783989e-6 5431/5435/5433/8732/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/5440/902/5430/5441/8731/5437/2968/1022 27 Human_herpesvirus_1 R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress 27/6371 27/10654 9.143711457177548e-7 3.3886930649697368e-6 1.3035378123783989e-6 5393/23404/3576/4801/6347/11340/468/3484/1054/8570/23016/118460/5073/1051/4800/22926/51010/56915/167227/22894/440/9709/4802/1649/51013/467/54512 27 Human_herpesvirus_1 R-HSA-5654716 Downstream signaling of activated FGFR4 27/6371 27/10654 9.143711457177548e-7 3.3886930649697368e-6 1.3035378123783989e-6 5295/4893/5335/9965/2264/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/2251/5781/6464/6654/2549/8822/8817/10817/2254/152831/26281/10818 27 Human_herpesvirus_1 R-HSA-76066 RNA Polymerase III Transcription Initiation From Type 2 Promoter 27/6371 27/10654 9.143711457177548e-7 3.3886930649697368e-6 1.3035378123783989e-6 55718/2976/5435/9328/84265/9330/2972/2975/10622/661/55814/11128/9533/5434/10623/112495/9329/6908/51728/171568/10621/5440/5441/51082/55703/27297/5437 27 Human_herpesvirus_1 R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 27/6371 27/10654 9.143711457177548e-7 3.3886930649697368e-6 1.3035378123783989e-6 5431/5435/5433/8732/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/5440/902/5430/5441/8731/5437/2968/1022 27 Human_herpesvirus_1 R-HSA-912526 Interleukin receptor SHC signaling 27/6371 27/10654 9.143711457177548e-7 3.3886930649697368e-6 1.3035378123783989e-6 5295/5777/1437/5291/3558/3717/3563/2885/9846/3635/5290/1439/3718/3567/3562/6464/1438/8503/3636/6654/3716/5293/3561/3568/3560/5296/3559 27 Human_herpesvirus_1 R-HSA-163359 Glucagon signaling in metabolic regulation 32/6371 33/10654 9.632044445758024e-7 3.532583573353332e-6 1.3588885670570447e-6 2788/107/2782/2787/5567/112/5573/111/2785/2783/2784/196883/115/2791/5568/113/5566/2641/2786/5577/109/54331/5575/59345/51764/94235/114/108/55970/2778/5576/2790 32 Human_herpesvirus_1 R-HSA-2559585 Oncogene Induced Senescence 32/6371 33/10654 9.632044445758024e-7 3.532583573353332e-6 1.3588885670570447e-6 2077/27327/5925/2114/1869/4194/1031/192669/1032/1030/4343/7314/7027/5594/6667/7157/6233/26523/1019/1029/1870/7311/3397/2113/5595/57690/192670/7316/1871/1021/23112/4193 32 Human_herpesvirus_1 R-HSA-389356 CD28 co-stimulation 32/6371 33/10654 9.632044445758024e-7 3.532583573353332e-6 1.3588885670570447e-6 5295/941/2534/2885/2475/5062/5879/1326/5290/57761/9020/6714/10000/7525/7409/3932/940/253260/5170/64223/8503/4067/5063/998/208/79109/5058/9402/207/55615/942/5296 32 Human_herpesvirus_1 R-HSA-5654726 Negative regulation of FGFR1 signaling 32/6371 33/10654 9.632044445758024e-7 3.532583573353332e-6 1.3588885670570447e-6 2250/8569/2885/5518/2253/7314/5515/5594/8074/2260/2249/6714/2248/2247/6233/2246/2251/5781/673/9365/7311/5595/5516/8822/10253/2254/7316/26281/10818/867/2255/27006 32 Human_herpesvirus_1 R-HSA-381119 Unfolded Protein Response (UPR) 78/6371 94/10654 1.0505205185523977e-6 3.842836715533641e-6 1.4782344902455337e-6 5393/10525/1965/2673/1663/23404/5526/811/3576/9570/55738/10130/3309/4801/55062/6745/6347/11340/9820/10488/8720/9695/84699/7094/9114/58477/468/3484/22872/51726/3068/1054/8894/7466/9451/2931/64061/8570/23016/148327/118460/1968/1200/6464/37/5073/7184/7494/118/10897/1051/84447/5611/4800/1639/11015/10954/22926/90993/51010/56915/167227/22894/4000/10113/440/9709/4802/116138/1649/2081/30827/51013/467/27230/10106/54512/7709 78 Human_herpesvirus_1 R-HSA-111996 Ca-dependent events 36/6371 38/10654 1.0880980656951562e-6 3.939472996824515e-6 1.515407832385157e-6 817/5578/5582/107/814/818/5567/5594/112/5573/111/5613/5580/5153/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5321/5575/114/108/5576/1385/808/5137 36 Human_herpesvirus_1 R-HSA-3232142 SUMOylation of ubiquitinylation proteins 36/6371 38/10654 1.0880980656951562e-6 3.939472996824515e-6 1.515407832385157e-6 23165/348995/57122/23511/23279/23225/7428/5371/9972/8021/55746/51588/10762/79902/9883/9063/6396/129401/8554/4928/5903/55706/7175/4927/8086/7329/81929/9631/79023/23636/53371/9688/7341/5987/8480/4193 36 Human_herpesvirus_1 R-HSA-420499 Class C/3 (Metabotropic glutamate/pheromone receptors) 36/6371 38/10654 1.0880980656951562e-6 3.939472996824515e-6 1.515407832385157e-6 50833/5726/2550/50832/259294/2912/259295/9568/2911/2914/259296/259289/50835/338398/2916/259293/54429/80835/50840/2913/2918/50838/83756/259286/259287/50836/846/259290/80834/259292/50834/259285/2917/50831/50839/50837 36 Human_herpesvirus_1 R-HSA-5696394 DNA Damage Recognition in GG-NER 36/6371 38/10654 1.0880980656951562e-6 3.939472996824515e-6 1.515407832385157e-6 10445/9978/10980/10987/7314/83444/86/1643/29844/10920/6233/93973/8607/5886/8451/8450/1642/142/125476/1069/2873/7311/60/8533/10038/51138/7528/9318/7316/64708/283899/79913/54617/5887/50813/7508 36 Human_herpesvirus_1 R-HSA-6806834 Signaling by MET 67/6371 79/10654 1.2386814858482374e-6 4.473192475748622e-6 1.7207151613883175e-6 5295/3675/4893/5770/10653/3249/5908/3082/1280/3688/3910/6456/30011/2885/3845/3265/1399/7314/5879/3918/5290/8027/2060/284217/9101/6714/9146/6455/2335/64759/3909/84951/6233/57610/5781/6464/85440/5747/382/1277/3912/6774/4233/5795/2889/5771/3913/6654/5867/7311/2549/53916/26018/10048/7316/3915/1281/3673/867/3914/200958/1398/5906/23163/1278/10254/6457 67 Human_herpesvirus_1 R-HSA-4570464 SUMOylation of RNA binding proteins 43/6371 47/10654 1.282635685023664e-6 4.620106089932177e-6 1.777228822428063e-6 1912/23165/6045/80012/348995/6613/57122/23511/3190/1911/23279/23225/57332/9972/8021/55746/51602/10762/79902/9883/84733/6396/129401/7703/6015/4928/5903/55706/7175/8535/4927/8086/7329/648/81929/9631/79023/23636/3183/53371/9688/7341/8480 43 Human_herpesvirus_1 R-HSA-5617833 Cilium Assembly 152/6371 201/10654 1.4036320495421732e-6 5.043074946446688e-6 1.939933407161541e-6 55763/57728/79738/79867/7531/11190/203068/11127/54801/51807/85302/347688/79441/10381/5116/5048/10576/22832/60412/192668/8655/83658/6010/89891/9702/132320/7846/7840/11064/84902/81027/2847/5518/55835/23332/93323/79659/3797/10575/1454/112752/9321/10013/54806/91147/983/79959/5310/8729/10376/10540/11336/117177/57545/26005/54930/54820/23322/378/56623/1453/9793/4218/140735/57576/6102/84617/11258/22981/8636/54903/80776/3842/7532/55125/10382/6753/79809/121441/7277/55112/26146/9814/23354/146057/9738/1639/55722/4957/5566/7283/347733/22919/27077/22994/4867/5311/1069/5577/10383/5347/403/84790/22948/80184/22897/22920/5108/261734/57787/7280/10806/9657/1778/55770/23265/115106/10694/22995/55559/9371/10142/10640/51134/95681/57539/79989/112714/7203/1781/80321/8766/79598/149371/10121/347240/84131/6950/55212/3320/79600/10733/4751/80254/200894/26123/54536/9662/55142/8481/51259/55755 152 Human_herpesvirus_1 R-HSA-1971475 A tetrasaccharide linker sequence is required for GAG synthesis 26/6371 26/10654 1.5315896826931943e-6 5.488844243560381e-6 2.111408699625136e-6 10675/126792/6385/27087/135152/1463/221914/6382/63827/633/375790/2262/11285/9672/64132/64131/1464/2239/2719/26229/2817/3339/1634/6383/1462/10082 26 Human_herpesvirus_1 R-HSA-397795 G-protein beta:gamma signalling 31/6371 32/10654 1.566955820672155e-6 5.573152692163937e-6 2.143839860710147e-6 2788/5331/2782/2787/10681/2792/146850/10000/5294/2785/2783/2784/2791/5170/23236/998/695/2786/208/387/5058/54331/59345/207/9459/51764/94235/55970/2793/23533/2790 31 Human_herpesvirus_1 R-HSA-5656169 Termination of translesion DNA synthesis 31/6371 32/10654 1.566955820672155e-6 5.573152692163937e-6 2.143839860710147e-6 5982/6117/10714/7314/6118/9636/11201/51455/5985/5984/6233/5424/124739/54107/7706/5425/5111/6119/5427/5429/9246/51426/7311/7318/5983/56655/57804/7316/5426/9100/5981 31 Human_herpesvirus_1 R-HSA-69190 DNA strand elongation 31/6371 32/10654 1.566955820672155e-6 5.573152692163937e-6 2.143839860710147e-6 2237/1763/5982/5422/4174/84515/6117/10714/5558/6118/64785/3978/5557/5985/4175/5984/23649/5424/4172/8318/4173/5425/5111/6119/51659/5983/4176/57804/9837/4171/5981 31 Human_herpesvirus_1 R-HSA-351202 Metabolism of polyamines 52/6371 59/10654 1.6535873156078425e-6 5.866495702608727e-6 2.2566809173595524e-6 5689/5682/143471/5705/5709/5695/5711/4946/5683/5699/5702/5696/5691/5718/1728/51582/5700/122706/5707/23198/6723/9861/5698/5692/5713/5710/5719/196743/6303/5706/5714/5688/5687/5708/5704/5694/5684/5720/5690/51686/5717/9491/10197/10213/5715/6611/5701/5685/5686/5716/5693/5721 52 Human_herpesvirus_1 R-HSA-69481 G2/M Checkpoints 129/6371 168/10654 2.149467518599818e-6 7.606636932989832e-6 2.9260657950072713e-6 5689/83990/5682/9156/1763/7531/7486/10971/5982/7533/2810/11200/143471/472/5705/5709/4174/5695/84515/4998/5711/4683/10926/5683/990/165918/84126/5699/5702/8924/55388/672/6117/7334/5001/7465/5696/83695/5691/7314/5718/6118/23594/5700/122706/5707/51588/51720/23198/63967/7534/993/116028/983/9861/9656/5698/5692/5985/5713/4175/5710/7157/5984/5719/6233/7158/5884/5810/4999/4172/80010/5000/8318/51512/7532/4173/5706/9133/580/11073/891/641/5714/6119/3364/10524/5688/5687/144715/5708/1111/5704/23595/7311/5983/5694/4176/7529/1017/5684/5720/5883/10111/8317/5690/5717/9491/545/10197/7336/29086/7316/10213/4171/5715/9088/7341/5701/5685/5686/995/5716/5932/9025/79184/7156/5693/5721 129 Human_herpesvirus_1 R-HSA-373760 L1CAM interactions 95/6371 119/10654 2.360462984878276e-6 8.332434336620314e-6 3.205260263676817e-6 9252/6711/71/7430/1459/51807/286/347688/1785/1460/10381/4684/3688/1457/285643/5605/7846/1463/3690/1808/81027/6456/1741/1739/3786/6709/5962/163/6196/1759/6197/6334/3312/100133941/5879/6331/6900/6326/161/5594/284217/2260/3672/8650/1272/6714/10376/6195/214/7410/51332/3685/1213/1211/1175/1173/84617/6712/3674/10382/7277/3678/4478/160/3912/3785/26052/6710/27330/347733/6386/2048/3897/10383/24137/1956/60/84790/5058/8506/7280/5595/6328/5604/10048/112714/3915/57731/3673/6708/1742/287/3680/288/2596 95 Human_herpesvirus_1 R-HSA-1839124 FGFR1 mutant receptor activation 30/6371 31/10654 2.5467128612797136e-6 8.770400310554813e-6 3.3737338305101265e-6 5295/11052/2250/9530/613/6776/11064/2885/9846/2253/7750/8805/26127/5290/8074/2260/2249/399687/2247/2246/2251/6777/1523/9208/6774/6772/11160/8822/2254/26281 30 Human_herpesvirus_1 R-HSA-2022928 HS-GAG biosynthesis 30/6371 31/10654 2.5467128612797136e-6 8.770400310554813e-6 3.3737338305101265e-6 6385/9653/3340/9956/64579/26035/221914/9348/64711/6382/90161/8509/375790/9957/9955/2262/9672/2132/222537/266722/9953/2239/2719/2131/9951/2817/3339/6383/9394/10082 30 Human_herpesvirus_1 R-HSA-5654687 Downstream signaling of activated FGFR1 30/6371 31/10654 2.5467128612797136e-6 8.770400310554813e-6 3.3737338305101265e-6 5295/4893/2250/5335/2885/2253/3845/3265/5290/23768/8074/2260/2249/2248/2247/2246/2251/5781/6464/23767/9365/6654/2549/8822/10817/2254/26281/10818/2255/27006 30 Human_herpesvirus_1 R-HSA-1643713 Signaling by EGFR in Cancer 25/6371 25/10654 2.565279977520636e-6 8.770400310554813e-6 3.3737338305101265e-6 5295/374/4893/5335/7039/2885/3845/3265/7314/1839/5290/2069/6233/255324/6464/6654/7311/1956/2549/11140/685/7316/1950/867/3320 25 Human_herpesvirus_1 R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 25/6371 25/10654 2.565279977520636e-6 8.770400310554813e-6 3.3737338305101265e-6 11065/7321/8697/51529/29945/51434/9184/29882/7314/996/51433/119504/7324/64682/6233/246184/8881/10393/7311/25906/991/7316/4085/4751/701 25 Human_herpesvirus_1 R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 25/6371 25/10654 2.565279977520636e-6 8.770400310554813e-6 3.3737338305101265e-6 9252/1848/1432/6196/5518/6197/51231/5515/1849/5594/5528/9261/5519/5598/4208/6195/5600/1846/5595/5516/1845/4205/466/2002/1385 25 Human_herpesvirus_1 R-HSA-392451 G beta:gamma signalling through PI3Kgamma 25/6371 25/10654 2.565279977520636e-6 8.770400310554813e-6 3.3737338305101265e-6 2788/2782/2787/10681/2792/146850/10000/5294/2785/2783/2784/2791/5170/2786/208/387/54331/59345/207/51764/94235/55970/2793/23533/2790 25 Human_herpesvirus_1 R-HSA-400685 Sema4D in semaphorin signaling 25/6371 25/10654 2.565279977520636e-6 8.770400310554813e-6 3.3737338305101265e-6 2909/388/2064/23365/79784/9475/4628/6093/10507/5879/27289/389/5364/10627/4233/387/4629/3984/4627/3985/10398/9826/4637/103910/6237 25 Human_herpesvirus_1 R-HSA-5654700 FRS-mediated FGFR2 signaling 25/6371 25/10654 2.565279977520636e-6 8.770400310554813e-6 3.3737338305101265e-6 4893/2250/2885/2252/2253/3845/3265/8823/8074/2249/2248/2247/2246/2251/5781/2263/6654/8822/8817/10817/2254/26281/10818/2255/27006 25 Human_herpesvirus_1 R-HSA-5654708 Downstream signaling of activated FGFR3 25/6371 25/10654 2.565279977520636e-6 8.770400310554813e-6 3.3737338305101265e-6 5295/4893/2250/5335/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/5781/6464/6654/2549/8822/8817/10817/2254/26281/10818/2261 25 Human_herpesvirus_1 R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 25/6371 25/10654 2.565279977520636e-6 8.770400310554813e-6 3.3737338305101265e-6 2308/2475/84335/7249/2932/10000/2931/253260/5170/572/4303/6199/64223/208/79109/1147/2309/842/207/1027/1026/55615/3164/1385/4193 25 Human_herpesvirus_1 R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 25/6371 25/10654 2.565279977520636e-6 8.770400310554813e-6 3.3737338305101265e-6 5982/6117/10714/7314/6118/3978/5985/5984/6233/5424/7515/54107/5425/5111/6119/5427/51426/7311/3980/5983/56655/57804/7316/5426/5981 25 Human_herpesvirus_1 R-HSA-9006335 Signaling by Erythropoietin 25/6371 25/10654 2.565279977520636e-6 8.770400310554813e-6 3.3737338305101265e-6 5295/4893/5335/5291/6776/3717/2885/2056/8660/3845/3265/1399/5290/5336/5294/2057/7409/6777/6464/2889/4067/6654/5293/2549/23533 25 Human_herpesvirus_1 R-HSA-195258 RHO GTPase Effectors 235/6371 327/10654 2.615372183911452e-6 8.92006165140814e-6 3.4313044670691817e-6 55839/11130/64837/71/6249/51517/5579/9735/7531/5526/51807/10971/5578/9212/347688/3798/388/7533/2810/147841/348995/10381/57122/6280/1780/23122/3688/5048/57405/8655/10094/23279/1432/2017/2491/7846/79784/9475/1060/81027/4628/11004/8976/1855/2885/23433/6093/9184/8826/10499/5518/23332/25909/10726/81930/5062/55746/5879/5515/85415/25/79682/1072/10403/4638/25936/4659/10093/1856/10006/4771/389/5594/3619/64105/7534/94274/332/5528/6714/79902/3796/5519/81565/999/89953/10810/5880/91687/11243/10376/11113/83540/5580/1857/128239/9055/7514/23191/147700/54820/29984/1729/6396/1535/5600/801/64946/9793/30849/10109/5586/140735/5500/4221/805/3831/220134/5170/84617/4928/4688/5590/5903/653361/55055/5747/80776/1783/401541/2316/7532/10382/10627/79172/7277/79980/6232/5501/10152/6279/54821/10092/9183/10163/1062/699/752/347733/22919/55845/5063/3895/5529/51143/998/695/10788/354/10097/57120/367/10383/5347/387/60/84790/84643/5058/7280/4629/7529/5595/64130/1778/5516/5905/81929/3984/27035/54908/55143/1495/1499/5525/4690/1058/991/79019/4627/348235/80152/10458/1063/3985/6722/8379/1027/1080/23421/55920/79023/112714/6242/1781/10398/4085/5289/5585/5216/10552/81624/55166/4637/51466/995/79003/391/23028/1742/5527/4689/10096/7454/701/23380/9928/29941/3799/103910/57551/5300/808/10095/1536 235 Human_herpesvirus_1 R-HSA-111933 Calmodulin induced events 34/6371 36/10654 2.750318189505831e-6 9.290548525316349e-6 3.5738206642785413e-6 817/5578/5582/107/814/818/5567/112/5573/111/5613/5580/5153/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5575/114/108/5576/1385/808/5137 34 Human_herpesvirus_1 R-HSA-111997 CaM pathway 34/6371 36/10654 2.750318189505831e-6 9.290548525316349e-6 3.5738206642785413e-6 817/5578/5582/107/814/818/5567/112/5573/111/5613/5580/5153/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5575/114/108/5576/1385/808/5137 34 Human_herpesvirus_1 R-HSA-176033 Interactions of Vpr with host cellular proteins 34/6371 36/10654 2.750318189505831e-6 9.290548525316349e-6 3.5738206642785413e-6 23165/348995/57122/23511/292/23279/23225/3836/9972/8021/55746/10762/79902/11168/9883/6396/129401/4928/5903/55706/7175/293/4927/8086/81929/9631/3159/79023/23636/53371/9688/8815/8480/291 34 Human_herpesvirus_1 R-HSA-177243 Interactions of Rev with host cellular proteins 34/6371 36/10654 2.750318189505831e-6 9.290548525316349e-6 3.5738206642785413e-6 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/5902/7514/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/1104/5905/3837/81929/9631/79023/23636/53371/9688/8480 34 Human_herpesvirus_1 R-HSA-165159 mTOR signalling 37/6371 40/10654 3.82609027216103e-6 1.2893650272771777e-5 4.9598356498808986e-6 5563/53632/6198/29904/10325/2475/10670/92335/64121/84335/51422/7249/1981/5494/1977/1978/57521/28956/6194/389541/58528/64223/5571/6794/6009/208/1975/55004/5562/5564/5565/7248/7529/207/153129/8649/10542 37 Human_herpesvirus_1 R-HSA-114452 Activation of BH3-only proteins 29/6371 30/10654 4.1348898445821005e-6 1.380251645520077e-5 5.3094516854656315e-6 7531/10971/7533/2810/1869/8655/90427/7159/637/23368/7027/7534/10000/7157/140735/572/7532/5366/8626/208/7161/7529/5533/27113/596/10018/207/5534/5599 29 Human_herpesvirus_1 R-HSA-3928663 EPHA-mediated growth cone collapse 29/6371 30/10654 4.1348898445821005e-6 1.380251645520077e-5 5.3094516854656315e-6 2042/2045/285220/79784/2534/9475/4628/6093/284656/2046/2041/6714/1943/2043/7525/1942/10627/1945/4067/2044/387/4629/4627/10398/4637/1946/103910/1944/1969 29 Human_herpesvirus_1 R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 29/6371 30/10654 4.1348898445821005e-6 1.380251645520077e-5 5.3094516854656315e-6 4893/817/1741/1739/6196/1740/6197/3845/3265/5923/818/5594/2902/6195/2906/801/4747/805/5170/2904/27330/816/5924/5595/815/1742/88/1385/808 29 Human_herpesvirus_1 R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 29/6371 30/10654 4.1348898445821005e-6 1.380251645520077e-5 5.3094516854656315e-6 7124/7375/10616/1540/3551/7314/257397/81858/8737/55072/23118/8517/7128/10454/6233/331/8717/330/27005/7311/1147/7186/56957/6885/7316/7132/329/9099/7185 29 Human_herpesvirus_1 R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 24/6371 24/10654 4.296348851590416e-6 1.4173935930947821e-5 5.452326629170327e-6 2237/1763/5982/5422/6117/10714/5558/6118/3978/5557/5985/5984/23649/5424/54107/5425/5111/6119/5427/5983/56655/57804/5426/5981 24 Human_herpesvirus_1 R-HSA-450302 activated TAK1 mediates p38 MAPK activation 24/6371 24/10654 4.296348851590416e-6 1.4173935930947821e-5 5.452326629170327e-6 1432/3654/7334/7314/257397/5606/8767/23118/8517/9261/10454/6233/5600/5608/387522/7867/64127/3656/7189/7311/6885/10392/7316/7335 24 Human_herpesvirus_1 R-HSA-5260271 Diseases of Immune System 24/6371 24/10654 4.296348851590416e-6 1.4173935930947821e-5 5.452326629170327e-6 4790/10333/4792/929/51135/7187/3551/8517/5970/7096/4791/81793/7098/695/81622/23643/1147/7099/4615/7100/114609/948/7097/148022 24 Human_herpesvirus_1 R-HSA-5602358 Diseases associated with the TLR signaling cascade 24/6371 24/10654 4.296348851590416e-6 1.4173935930947821e-5 5.452326629170327e-6 4790/10333/4792/929/51135/7187/3551/8517/5970/7096/4791/81793/7098/695/81622/23643/1147/7099/4615/7100/114609/948/7097/148022 24 Human_herpesvirus_1 R-HSA-982772 Growth hormone receptor signaling 24/6371 24/10654 4.296348851590416e-6 1.4173935930947821e-5 5.452326629170327e-6 5777/5770/9021/6776/3717/5618/6868/8660/1154/3667/2690/5594/5617/8835/6777/6774/6772/8651/1442/4067/2689/5595/25970/2688 24 Human_herpesvirus_1 R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 33/6371 35/10654 4.362844509958032e-6 1.43263638326994e-5 5.510961486262777e-6 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/7884/4927/10482/8086/22916/81929/9631/79023/23636/4686/53371/9688/10189/8480 33 Human_herpesvirus_1 R-HSA-8953750 Transcriptional Regulation by E2F6 33/6371 35/10654 4.362844509958032e-6 1.43263638326994e-5 5.510961486262777e-6 80314/6045/80012/79813/11335/1869/1911/5928/10138/23512/672/6241/5888/83746/7027/2146/1876/8726/8409/7703/317/23429/6015/84108/5931/1111/648/23468/23269/8317/4149/5932/10919 33 Human_herpesvirus_1 R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 71/6371 86/10654 4.667931745109754e-6 1.5292620937575343e-5 5.8826542446614566e-6 5295/5335/71/51517/5291/4651/2268/10094/2534/8976/2885/5879/25/1072/5290/10093/10006/5336/4771/5594/4644/4641/6714/10810/7525/7410/5580/7409/23191/10109/2214/5747/2209/10451/6850/10152/5337/10092/4650/10163/4067/55845/998/695/3326/10097/60/5058/63916/5595/3984/23646/4690/4627/10458/3708/919/3055/10552/10768/4620/917/3320/1398/10096/7454/5296/5581/5338/10095/2212 71 Human_herpesvirus_1 R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 49/6371 56/10654 5.368515470775033e-6 1.754709223318136e-5 6.749887872611884e-6 79718/5469/1387/6907/2101/84808/10499/23054/1386/9572/85441/3054/7019/814/96764/23408/5465/7978/64784/4208/6604/6742/801/133522/64216/805/4899/5442/3418/23082/23410/4209/2553/2551/6648/51106/23373/2746/8841/200186/9611/23409/54205/6256/10498/1385/808/8648/10891 49 Human_herpesvirus_1 R-HSA-2980766 Nuclear Envelope Breakdown 46/6371 52/10654 5.382226221099227e-6 1.7551278115917112e-5 6.7514980675512375e-6 23165/5579/91754/5578/348995/57122/23511/23279/23225/9663/4001/9972/8021/55746/10762/983/79902/9883/221496/7444/2010/64900/23175/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/5347/7112/4000/81929/9631/79023/23636/7443/53371/9688/8815/23592/8480 46 Human_herpesvirus_1 R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 36/6371 39/10654 5.949618099980404e-6 1.93568220211344e-5 7.446041570676421e-6 9134/10528/10576/10574/6468/10564/54461/10693/8877/10575/898/10517/26985/26190/10238/7157/83752/26224/2629/8237/63971/6774/26272/26270/55135/22948/84261/10694/8841/22803/7203/908/6950/55294/6499/26234 36 Human_herpesvirus_1 R-HSA-5218920 VEGFR2 mediated vascular permeability 28/6371 29/10654 6.706286007530949e-6 2.1718522574847935e-5 8.354523370077184e-6 857/2475/5062/5879/57761/1500/10000/3728/7410/7409/801/253260/805/5170/10451/64223/1003/5063/208/79109/5058/1495/1499/207/55615/3320/4846/808 28 Human_herpesvirus_1 R-HSA-8863795 Downregulation of ERBB2 signaling 28/6371 29/10654 6.706286007530949e-6 2.1718522574847935e-5 8.354523370077184e-6 26469/2064/145957/4145/9542/7314/1839/2065/2069/9101/10000/6233/5782/10193/3084/208/10718/7311/1956/11140/8065/685/10273/207/7316/1950/3320/2066 28 Human_herpesvirus_1 R-HSA-159227 Transport of the SLBP independent Mature mRNA 32/6371 34/10654 6.909766110467838e-6 2.2174067609046787e-5 8.52975912201293e-6 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10482/8086/22916/81929/9631/79023/23636/4686/53371/9688/10189/8480 32 Human_herpesvirus_1 R-HSA-165054 Rev-mediated nuclear export of HIV RNA 32/6371 34/10654 6.909766110467838e-6 2.2174067609046787e-5 8.52975912201293e-6 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/5902/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/1104/5905/81929/9631/79023/23636/53371/9688/8480 32 Human_herpesvirus_1 R-HSA-187687 Signalling to ERKs 32/6371 34/10654 6.909766110467838e-6 2.2174067609046787e-5 8.52975912201293e-6 4893/5605/5898/1432/5603/2885/3845/3265/1399/5899/5594/9261/6714/4914/5600/6300/6464/673/7867/2889/6654/5900/7529/5595/25759/5604/57498/10818/53358/4803/1398/5906 32 Human_herpesvirus_1 R-HSA-4085377 SUMOylation of SUMOylation proteins 32/6371 34/10654 6.909766110467838e-6 2.2174067609046787e-5 8.52975912201293e-6 23165/348995/6613/57122/23511/23279/23225/9972/8021/55746/51588/10762/79902/9883/6396/129401/4928/5903/55706/7175/10210/4927/8086/7329/81929/9631/79023/23636/53371/9688/7341/8480 32 Human_herpesvirus_1 R-HSA-75893 TNF signaling 39/6371 43/10654 7.102306409230776e-6 2.262690187164354e-5 8.703952114036132e-6 7124/25999/7375/9530/8439/10616/6868/1540/3551/7314/257397/90268/81858/8737/55072/23118/841/8517/8887/7128/10454/6233/8772/331/8717/330/27005/8567/7311/1147/7186/56957/6885/7316/7132/329/9099/55512/7185 39 Human_herpesvirus_1 R-HSA-166208 mTORC1-mediated signalling 23/6371 23/10654 7.195098399694015e-6 2.262690187164354e-5 8.703952114036132e-6 6198/29904/10325/2475/10670/64121/84335/1981/1977/1978/57521/28956/6194/389541/58528/64223/6009/1975/55004/7529/153129/8649/10542 23 Human_herpesvirus_1 R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 23/6371 23/10654 7.195098399694015e-6 2.262690187164354e-5 8.703952114036132e-6 5431/5435/5433/5439/51497/5438/7936/6829/25920/2963/5434/5436/2962/5432/22916/5440/5430/5441/7469/4686/9150/5437/6827 23 Human_herpesvirus_1 R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 23/6371 23/10654 7.195098399694015e-6 2.262690187164354e-5 8.703952114036132e-6 11065/7321/8697/51529/29945/51434/29882/7314/996/983/51433/119504/7324/64682/6233/246184/8881/891/10393/7311/25906/991/7316 23 Human_herpesvirus_1 R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 23/6371 23/10654 7.195098399694015e-6 2.262690187164354e-5 8.703952114036132e-6 7321/8239/9612/4089/23327/4088/7314/6497/51592/7323/7050/5494/6233/60436/142/4087/7311/64750/54778/7316/9611/3065/6498 23 Human_herpesvirus_1 R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 23/6371 23/10654 7.195098399694015e-6 2.262690187164354e-5 8.703952114036132e-6 3654/7334/7314/257397/5601/8767/23118/8517/10454/6233/387522/64127/5602/3656/7189/7311/6416/6885/10392/7316/7335/5609/5599 23 Human_herpesvirus_1 R-HSA-5654693 FRS-mediated FGFR1 signaling 23/6371 23/10654 7.195098399694015e-6 2.262690187164354e-5 8.703952114036132e-6 4893/2250/2885/2253/3845/3265/8074/2260/2249/2248/2247/2246/2251/5781/9365/6654/8822/10817/2254/26281/10818/2255/27006 23 Human_herpesvirus_1 R-HSA-5654695 PI-3K cascade:FGFR2 23/6371 23/10654 7.195098399694015e-6 2.262690187164354e-5 8.703952114036132e-6 5295/2250/2885/2252/2253/5290/8823/8074/2249/2248/2247/2246/2251/5781/2263/2549/8822/8817/2254/26281/10818/2255/27006 23 Human_herpesvirus_1 R-HSA-5654699 SHC-mediated cascade:FGFR2 23/6371 23/10654 7.195098399694015e-6 2.262690187164354e-5 8.703952114036132e-6 4893/2250/2885/2252/2253/3845/3265/8823/8074/2249/2248/2247/2246/2251/6464/2263/6654/8822/8817/2254/26281/2255/27006 23 Human_herpesvirus_1 R-HSA-437239 Recycling pathway of L1 42/6371 47/10654 7.77595265555019e-6 2.434511119653408e-5 9.36490038572505e-6 9252/71/7430/51807/347688/1785/10381/285643/7846/1808/81027/6456/5962/163/6196/1759/6197/161/5594/8650/6714/10376/6195/1213/1211/1175/1173/84617/10382/7277/4478/160/26052/27330/347733/3897/10383/24137/60/84790/7280/112714 42 Human_herpesvirus_1 R-HSA-9020591 Interleukin-12 signaling 42/6371 47/10654 7.77595265555019e-6 2.434511119653408e-5 9.36490038572505e-6 3593/5908/3313/6175/3936/5898/3717/3181/4001/3594/4282/5062/1072/3592/6627/9049/27250/9987/3185/3458/5478/302/552900/7297/6775/9446/3595/4478/998/6648/3716/2939/6888/3586/829/6647/6950/4507/6845/375/5721/5034 42 Human_herpesvirus_1 R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF) 48/6371 55/10654 7.91264881585374e-6 2.4718274619436904e-5 9.508446178343107e-6 79718/51141/10484/3638/5469/1387/6907/4801/9632/6309/10499/23054/85441/31/96764/4598/8720/5465/2222/6667/3156/6604/10654/6319/6721/10802/9453/4800/57678/32/1595/5901/4047/9871/3837/4802/6720/2194/22937/4597/1717/6256/10498/2224/3422/4520/8648/10427 48 Human_herpesvirus_1 R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 45/6371 51/10654 8.017254565614634e-6 2.4989764782887116e-5 9.612881040681194e-6 51807/347688/10381/1780/5048/8655/84516/832/636/7846/2590/81027/51164/23299/5870/10376/10540/140735/84617/11258/1783/10382/93661/55860/830/7277/10671/1639/347733/51143/10383/84790/5049/7280/829/22931/1778/5321/5050/112714/1781/22930/25782/10121/51560 45 Human_herpesvirus_1 R-HSA-111465 Apoptotic cleavage of cellular proteins 35/6371 38/10654 9.233599436271546e-6 2.859175965792856e-5 1.0998470242650319e-5 2339/660/836/324/9414/4001/6709/6093/840/2934/22985/63967/841/100506658/7082/5339/5317/10134/999/5588/5580/839/1828/5747/118/1829/8428/1832/4000/51765/1499/329/4137/7431/6304 35 Human_herpesvirus_1 R-HSA-5689896 Ovarian tumor domain proteases 35/6371 38/10654 9.233599436271546e-6 2.859175965792856e-5 1.0998470242650319e-5 7321/55432/324/64135/7187/7314/8737/8767/55611/8517/80124/983/2099/23586/7128/7157/6233/55593/84282/10318/7706/79155/79589/64127/7189/7311/387/56957/10392/57506/7316/7415/5728/78990/54764 35 Human_herpesvirus_1 R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 35/6371 38/10654 9.233599436271546e-6 2.859175965792856e-5 1.0998470242650319e-5 1912/1459/6045/80012/1460/28996/1457/1911/6603/10138/57332/57492/196528/86/865/51412/84733/6604/8289/6602/23429/55193/6015/6595/6597/8535/6599/648/6601/23466/6598/2033/84333/6605/861 35 Human_herpesvirus_1 R-HSA-1489509 DAG and IP3 signaling 38/6371 42/10654 1.0837888278917994e-5 3.3390139039034284e-5 1.2844275938677272e-5 5335/817/5578/5582/107/814/818/5567/112/5573/111/5613/5580/5153/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5575/114/3708/108/10768/5576/1385/5581/808/5137 38 Human_herpesvirus_1 R-HSA-69205 G1/S-Specific Transcription 27/6371 28/10654 1.0864384664297505e-5 3.3390139039034284e-5 1.2844275938677272e-5 5422/1869/4998/5928/990/8900/6241/7027/898/5934/1876/983/7298/1719/26271/8318/286826/5111/91750/1874/81620/55957/1875/5933/3065/7083/132660 27 Human_herpesvirus_1 R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 31/6371 33/10654 1.0925102150165608e-5 3.3390139039034284e-5 1.2844275938677272e-5 23165/348995/57122/23511/23279/23225/9972/8021/55746/3303/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/3304/81929/9631/79023/23636/53371/9688/8480 31 Human_herpesvirus_1 R-HSA-180746 Nuclear import of Rev protein 31/6371 33/10654 1.0925102150165608e-5 3.3390139039034284e-5 1.2844275938677272e-5 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/1104/3837/81929/9631/79023/23636/53371/9688/8480 31 Human_herpesvirus_1 R-HSA-180910 Vpr-mediated nuclear import of PICs 31/6371 33/10654 1.0925102150165608e-5 3.3390139039034284e-5 1.2844275938677272e-5 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/11168/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/3159/79023/23636/53371/9688/8815/8480 31 Human_herpesvirus_1 R-HSA-2871809 FCERI mediated Ca+2 mobilization 31/6371 33/10654 1.0925102150165608e-5 3.3390139039034284e-5 1.2844275938677272e-5 5335/5530/2885/7294/4773/5336/7410/7409/3702/801/805/6464/2205/4772/3937/4775/10451/2206/6850/4067/695/6654/7006/9402/5532/3708/10768/27040/5534/808/2207 31 Human_herpesvirus_1 R-HSA-1250196 SHC1 events in ERBB2 signaling 22/6371 22/10654 1.2048871662552661e-5 3.6275067777237437e-5 1.3954029352210018e-5 4893/5578/2064/145957/9542/2885/3845/3265/1839/2065/2069/5580/6464/5782/3084/6654/10718/1956/685/1950/2066/5581 22 Human_herpesvirus_1 R-HSA-198753 ERK/MAPK targets 22/6371 22/10654 1.2048871662552661e-5 3.6275067777237437e-5 1.3954029352210018e-5 9252/1848/1432/6196/5518/6197/51231/5515/1849/5594/5528/5519/5598/4208/6195/5600/1846/5595/5516/1845/4205/2002 22 Human_herpesvirus_1 R-HSA-392170 ADP signalling through P2Y purinoceptor 12 22/6371 22/10654 1.2048871662552661e-5 3.6275067777237437e-5 1.3954029352210018e-5 2788/64805/2770/2782/2773/2787/10681/2792/2785/2783/2784/2771/2791/2786/54331/59345/51764/94235/55970/346562/2793/2790 22 Human_herpesvirus_1 R-HSA-5654712 FRS-mediated FGFR4 signaling 22/6371 22/10654 1.2048871662552661e-5 3.6275067777237437e-5 1.3954029352210018e-5 4893/9965/2264/2885/2253/3845/3265/8823/8074/2249/2247/2246/2251/5781/6654/8822/8817/10817/2254/152831/26281/10818 22 Human_herpesvirus_1 R-HSA-5655332 Signaling by FGFR3 in disease 22/6371 22/10654 1.2048871662552661e-5 3.6275067777237437e-5 1.3954029352210018e-5 5295/4893/2250/5335/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/6654/2549/8822/8817/2254/26281/10818/2261 22 Human_herpesvirus_1 R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 22/6371 22/10654 1.2048871662552661e-5 3.6275067777237437e-5 1.3954029352210018e-5 5295/4893/2250/5335/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/6654/2549/8822/8817/2254/26281/10818/2261 22 Human_herpesvirus_1 R-HSA-912631 Regulation of signaling by CBL 22/6371 22/10654 1.2048871662552661e-5 3.6275067777237437e-5 1.3954029352210018e-5 5295/5291/2534/2885/1399/7314/5290/6233/7525/7409/6850/8503/2889/4067/29760/7311/5293/7316/3055/867/1398/5296 22 Human_herpesvirus_1 R-HSA-373755 Semaphorin interactions 55/6371 65/10654 1.3170849803248625e-5 3.9568595579121405e-5 1.5220959683037604e-5 5361/7305/2909/388/2064/5788/3688/23365/79784/2534/9475/1808/8482/4628/6093/10507/5062/5879/1400/27289/1072/7094/389/10371/5364/3672/9855/2932/64218/80031/9723/10154/57556/10627/4233/5063/3326/387/5058/1020/4629/3984/4627/3985/1809/9037/971/10398/9826/4637/3320/103910/8851/6237/2242 55 Human_herpesvirus_1 R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 52/6371 61/10654 1.4647424849745896e-5 4.391117598267772e-5 1.6891431942046897e-5 71/51517/4651/10094/8976/2885/5879/25/1072/10093/10006/4771/5594/4644/4641/10810/7410/7409/23191/10109/2214/5747/2209/10451/6850/10152/10092/4650/10163/55845/998/695/3326/10097/60/5058/63916/5595/3984/4690/4627/10458/919/10552/4620/917/3320/1398/10096/7454/10095/2212 52 Human_herpesvirus_1 R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 30/6371 32/10654 1.7243068470392924e-5 5.1583077712277135e-5 1.9842603324537797e-5 2788/2149/2769/408/2768/2782/2776/2787/5594/10681/2792/6714/2785/2783/2784/2791/2147/409/2786/5595/54331/59345/51764/94235/55970/2767/2793/9630/9002/2790 30 Human_herpesvirus_1 R-HSA-3899300 SUMOylation of transcription cofactors 40/6371 45/10654 1.7554035104149776e-5 5.236694422237357e-5 2.014413539491931e-5 1912/6045/80012/6613/28996/9612/1911/1387/57332/4152/115426/10499/6612/11315/3622/51588/1655/84733/10155/9063/7690/7703/6015/8554/8535/4869/10210/10521/1616/7329/25942/648/1487/8204/7341/10401/2033/6294/8648/10891 40 Human_herpesvirus_1 R-HSA-1538133 G0 and Early G1 26/6371 27/10654 1.7579271644054583e-5 5.236694422237357e-5 2.014413539491931e-5 9134/1869/4609/5928/990/8900/7027/7153/898/5934/993/890/983/1859/286826/5111/91750/1874/55957/1017/4605/4149/1875/5933/3065/132660 26 Human_herpesvirus_1 R-HSA-5689603 UCH proteinases 81/6371 102/10654 1.8958193304819865e-5 5.635572409769611e-5 2.167851023886327e-5 5689/221937/5682/4738/10445/143471/5705/5709/5695/11047/5711/7347/5683/55777/5699/5702/7040/7345/3054/5696/5691/7314/5718/3607/5700/122706/5707/83444/171023/23198/86/4092/9861/29844/7046/5698/5692/5713/5710/8473/9958/5719/6233/93973/8607/114785/5706/580/5714/5688/5687/5708/125476/5704/7048/7311/60/5694/7528/5684/5720/51377/5690/5717/9491/10197/7316/10213/8314/55252/5715/283899/5701/79913/5685/54617/5686/221656/5716/5693/5721 81 Human_herpesvirus_1 R-HSA-5632684 Hedgehog 'on' state 69/6371 85/10654 1.9954615032602134e-5 5.9103898183992717e-5 2.2735657867109172e-5 5689/5682/11127/22873/1452/51684/143471/5705/8452/5709/9978/5695/5711/5683/408/5699/5702/83737/6469/5696/5691/7314/5718/5700/122706/5707/23198/2737/5727/8650/9861/8405/5698/5692/5713/5710/5719/6233/91653/23288/409/79577/5706/5714/2736/5688/5687/5708/5704/7311/5694/57154/5684/5720/2735/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/5716/5693/5721 69 Human_herpesvirus_1 R-HSA-111931 PKA-mediated phosphorylation of CREB 21/6371 21/10654 2.0175693289436608e-5 5.9103898183992717e-5 2.2735657867109172e-5 107/5567/112/5573/111/5613/196883/115/801/805/5568/113/5566/5577/109/5575/114/108/5576/1385/808 21 Human_herpesvirus_1 R-HSA-389513 CTLA4 inhibitory signaling 21/6371 21/10654 2.0175693289436608e-5 5.9103898183992717e-5 2.2735657867109172e-5 5526/941/2534/5518/5515/5528/6714/5519/10000/7525/3932/5781/1493/4067/5529/208/5516/5525/207/942/5527 21 Human_herpesvirus_1 R-HSA-416572 Sema4D induced cell migration and growth-cone collapse 21/6371 21/10654 2.0175693289436608e-5 5.9103898183992717e-5 2.2735657867109172e-5 388/2064/23365/79784/9475/4628/6093/10507/27289/389/5364/10627/387/4629/3984/4627/3985/10398/9826/4637/103910 21 Human_herpesvirus_1 R-HSA-5654688 SHC-mediated cascade:FGFR1 21/6371 21/10654 2.0175693289436608e-5 5.9103898183992717e-5 2.2735657867109172e-5 4893/2250/2885/2253/3845/3265/8074/2260/2249/2248/2247/2246/2251/6464/9365/6654/8822/2254/26281/2255/27006 21 Human_herpesvirus_1 R-HSA-5654689 PI-3K cascade:FGFR1 21/6371 21/10654 2.0175693289436608e-5 5.9103898183992717e-5 2.2735657867109172e-5 5295/2250/2885/2253/5290/8074/2260/2249/2248/2247/2246/2251/5781/9365/2549/8822/2254/26281/10818/2255/27006 21 Human_herpesvirus_1 R-HSA-6807004 Negative regulation of MET activity 21/6371 21/10654 2.0175693289436608e-5 5.9103898183992717e-5 2.2735657867109172e-5 5770/3082/6456/30011/2885/7314/8027/2060/9101/9146/6455/6233/4233/5795/5771/7311/26018/7316/867/10254/6457 21 Human_herpesvirus_1 R-HSA-163685 Integration of energy metabolism 85/6371 108/10654 2.2462012104934723e-5 6.566534387612387e-5 2.5259667094140388e-5 2788/5563/5313/5331/2740/2770/5578/2769/107/9495/2782/3630/2776/8826/5518/31/777/2181/6513/5515/2787/5567/1131/51422/10681/112/5573/5528/111/2792/5519/51085/2785/2783/2784/2771/9370/7086/6844/2182/196883/115/2791/9254/5568/150/113/6616/5566/775/32/23236/6794/2641/6514/2786/5577/6888/773/5565/109/5516/54331/5575/59345/776/51764/94235/114/3708/4082/108/55970/2778/2194/2767/10768/152/2793/5576/948/47/5906/9630/2790 85 Human_herpesvirus_1 R-HSA-5685942 HDR through Homologous Recombination (HRR) 56/6371 67/10654 2.3396462300083907e-5 6.825579497462495e-5 2.6256142990089815e-5 83990/9156/1763/7486/5982/472/80198/4683/84126/672/6117/10714/348654/83695/7314/6118/5888/116028/7517/5985/5984/6233/5884/5810/5424/80010/54107/580/11073/5425/641/5111/6119/3364/10524/5427/144715/5429/1111/79728/51426/7311/5983/56655/51750/5883/10111/57804/675/545/7316/5426/10635/5932/7156/5981 56 Human_herpesvirus_1 R-HSA-445717 Aquaporin-mediated transport 45/6371 52/10654 2.4956722494642865e-5 7.265750961326953e-5 2.7949362576745997e-5 2788/358/360/107/554/2782/2787/22841/5567/10681/112/5573/111/2792/2785/2783/2784/196883/115/2791/5568/359/113/5566/282679/2786/5577/109/54331/5575/59345/51764/94235/89872/114/108/8766/55970/2778/2793/5576/4645/551/2790/4284 45 Human_herpesvirus_1 R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 29/6371 31/10654 2.7163456102466888e-5 7.875728956197792e-5 3.029578158191487e-5 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/3837/81929/9631/79023/23636/53371/9688/8480 29 Human_herpesvirus_1 R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 29/6371 31/10654 2.7163456102466888e-5 7.875728956197792e-5 3.029578158191487e-5 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/81929/9631/79023/23636/53371/9688/8480 29 Human_herpesvirus_1 R-HSA-6803529 FGFR2 alternative splicing 25/6371 26/10654 2.8407537348206818e-5 8.219557937636891e-5 3.1618397911291456e-5 54845/5431/5435/5433/5439/7072/7073/5438/3185/4670/5725/2963/5434/5436/2962/80004/5432/22916/5440/5430/3178/5441/4686/5437/3187 25 Human_herpesvirus_1 R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission 151/6371 206/10654 2.9995088248708972e-5 8.661158406375678e-5 3.3317114490009324e-5 2788/5563/4893/5579/5331/23426/2900/2770/51807/817/2550/5578/347688/5582/53632/10381/9463/107/9568/7846/55584/9495/2782/81027/1134/1741/1739/163/6196/1740/8874/6197/8825/3845/2561/3265/2560/814/2773/5879/2787/5923/818/161/55879/5567/4646/5594/51422/10681/112/2892/5573/2902/111/2901/2792/3359/6714/22843/2567/2566/2785/10376/6195/2783/2784/5613/2906/2771/196883/3759/115/1175/801/2891/7102/2791/2554/4747/57576/805/5170/1173/84617/3838/8573/2904/2890/10382/2556/5568/2036/7277/160/113/80852/10645/55327/5566/84254/2905/5571/27330/23236/347733/3084/816/2786/5577/10369/2893/5562/10383/84790/5564/5565/5924/7280/109/5595/64130/815/54331/28964/27020/5575/59345/2562/51764/94235/114/108/112714/55970/346562/2793/5576/2903/4137/2066/4905/1143/9647/1742/88/1385/808/8536/4193/2790 151 Human_herpesvirus_1 R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 20/6371 20/10654 3.3781817420858e-5 9.426862885029939e-5 3.6262570811655354e-5 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Human_herpesvirus_1 R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 20/6371 20/10654 3.3781817420858e-5 9.426862885029939e-5 3.6262570811655354e-5 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Human_herpesvirus_1 R-HSA-164938 Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 20/6371 20/10654 3.3781817420858e-5 9.426862885029939e-5 3.6262570811655354e-5 162/1174/567/163/55690/51606/161/10053/926/3932/1175/8907/940/1173/160/920/8905/164/130340/375 20 Human_herpesvirus_1 R-HSA-167044 Signalling to RAS 20/6371 20/10654 3.3781817420858e-5 9.426862885029939e-5 3.6262570811655354e-5 4893/5898/1432/5603/2885/3845/3265/5899/9261/6714/4914/5600/6300/6464/7867/6654/5900/25759/53358/4803 20 Human_herpesvirus_1 R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 20/6371 20/10654 3.3781817420858e-5 9.426862885029939e-5 3.6262570811655354e-5 7321/7334/3551/7314/11035/8737/8517/7323/6233/387522/330/7098/7189/7311/1147/7316/7335/7322/329/148022 20 Human_herpesvirus_1 R-HSA-3232118 SUMOylation of transcription factors 20/6371 20/10654 3.3781817420858e-5 9.426862885029939e-5 3.6262570811655354e-5 9112/6613/7022/6612/4286/6670/51588/7157/668/7158/9063/8554/7020/1029/7329/7021/3090/7341/10401/4193 20 Human_herpesvirus_1 R-HSA-3560783 Defective B4GALT7 causes EDS, progeroid type 20/6371 20/10654 3.3781817420858e-5 9.426862885029939e-5 3.6262570811655354e-5 10675/6385/1463/221914/6382/63827/633/375790/2262/11285/9672/1464/2239/2719/2817/3339/1634/6383/1462/10082 20 Human_herpesvirus_1 R-HSA-3560801 Defective B3GAT3 causes JDSSDHD 20/6371 20/10654 3.3781817420858e-5 9.426862885029939e-5 3.6262570811655354e-5 10675/6385/1463/221914/6382/63827/633/375790/2262/9672/1464/2239/2719/26229/2817/3339/1634/6383/1462/10082 20 Human_herpesvirus_1 R-HSA-4420332 Defective B3GALT6 causes EDSP2 and SEMDJL1 20/6371 20/10654 3.3781817420858e-5 9.426862885029939e-5 3.6262570811655354e-5 10675/126792/6385/1463/221914/6382/63827/633/375790/2262/9672/1464/2239/2719/2817/3339/1634/6383/1462/10082 20 Human_herpesvirus_1 R-HSA-5213460 RIPK1-mediated regulated necrosis 20/6371 20/10654 3.3781817420858e-5 9.426862885029939e-5 3.6262570811655354e-5 356/7314/11035/8737/841/8797/6233/8772/331/8717/8743/330/8837/197259/7311/8795/7186/355/7316/329 20 Human_herpesvirus_1 R-HSA-5218859 Regulated Necrosis 20/6371 20/10654 3.3781817420858e-5 9.426862885029939e-5 3.6262570811655354e-5 356/7314/11035/8737/841/8797/6233/8772/331/8717/8743/330/8837/197259/7311/8795/7186/355/7316/329 20 Human_herpesvirus_1 R-HSA-5654706 FRS-mediated FGFR3 signaling 20/6371 20/10654 3.3781817420858e-5 9.426862885029939e-5 3.6262570811655354e-5 4893/2250/2885/2253/3845/3265/8823/8074/2249/2247/2246/5781/6654/8822/8817/10817/2254/26281/10818/2261 20 Human_herpesvirus_1 R-HSA-5654719 SHC-mediated cascade:FGFR4 20/6371 20/10654 3.3781817420858e-5 9.426862885029939e-5 3.6262570811655354e-5 4893/9965/2264/2885/2253/3845/3265/8823/8074/2249/2247/2246/2251/6464/6654/8822/8817/2254/152831/26281 20 Human_herpesvirus_1 R-HSA-5654720 PI-3K cascade:FGFR4 20/6371 20/10654 3.3781817420858e-5 9.426862885029939e-5 3.6262570811655354e-5 5295/9965/2264/2885/2253/5290/8823/8074/2249/2247/2246/2251/5781/2549/8822/8817/2254/152831/26281/10818 20 Human_herpesvirus_1 R-HSA-69186 Lagging Strand Synthesis 20/6371 20/10654 3.3781817420858e-5 9.426862885029939e-5 3.6262570811655354e-5 2237/1763/5982/5422/6117/10714/5558/6118/3978/5557/5985/5984/23649/5424/5425/5111/6119/5983/57804/5981 20 Human_herpesvirus_1 R-HSA-8964616 G beta:gamma signalling through CDC42 20/6371 20/10654 3.3781817420858e-5 9.426862885029939e-5 3.6262570811655354e-5 2788/2782/2787/10681/2792/2785/2783/2784/2791/998/2786/5058/54331/59345/9459/51764/94235/55970/2793/2790 20 Human_herpesvirus_1 R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 20/6371 20/10654 3.3781817420858e-5 9.426862885029939e-5 3.6262570811655354e-5 22938/1387/4088/4853/9794/388585/2648/55534/3280/84441/8850/2324/10046/59/4855/23493/4851/23462/2033/3516 20 Human_herpesvirus_1 R-HSA-114604 GPVI-mediated activation cascade 32/6371 35/10654 3.4076929849239067e-5 9.471776564394795e-5 3.643534148820423e-5 5295/5777/5291/388/2534/51206/5879/5290/5336/146850/5880/5294/7410/7409/3932/5781/5170/5590/3937/10451/1277/6850/8503/4067/998/387/27040/23533/391/5296/1278/2207 32 Human_herpesvirus_1 R-HSA-432720 Lysosome Vesicle Biogenesis 32/6371 35/10654 3.4076929849239067e-5 9.471776564394795e-5 3.643534148820423e-5 8906/162/27243/1212/1174/1785/11154/408/6456/3312/10053/9146/4074/6844/1213/1211/23431/8907/351/9179/9829/8905/8673/164/1777/130340/1522/2799/81567/10717/6845/375 32 Human_herpesvirus_1 R-HSA-8986944 Transcriptional Regulation by MECP2 52/6371 62/10654 3.796146630075732e-5 1.0512045453704469e-4 4.043697222388181e-5 627/2290/79718/5770/817/9212/27327/6657/28996/9612/4988/6907/192669/4204/3654/4343/6750/814/818/6446/54487/4208/3066/26523/801/2891/805/2904/3930/54715/4233/6515/5566/816/25942/27161/815/8841/5468/4986/57690/192670/9611/2874/2289/2903/3064/5728/3065/23112/1385/808 52 Human_herpesvirus_1 R-HSA-76009 Platelet Aggregation (Plug Formation) 35/6371 39/10654 3.7968436128819257e-5 1.0512045453704469e-4 4.043697222388181e-5 5770/5908/2244/3690/2885/9564/7094/10125/6714/2335/1445/2266/2243/2147/5170/6464/5747/3674/1277/150/6850/6654/7450/7066/151/207/54518/152/4352/1398/2811/10235/5906/2815/1278 35 Human_herpesvirus_1 R-HSA-4090294 SUMOylation of intracellular receptors 28/6371 30/10654 4.270583228881493e-5 1.1777467810899744e-4 4.530470695112769e-5 7068/6613/7181/9759/8856/7067/6612/5914/7421/10062/51588/2516/5465/2099/9063/8554/5241/2908/9971/7329/367/6095/5468/4306/7341/10401/6256/7376 28 Human_herpesvirus_1 R-HSA-499943 Interconversion of nucleotide di- and triphosphates 28/6371 30/10654 4.270583228881493e-5 1.1777467810899744e-4 4.530470695112769e-5 56474/4832/654364/221264/7295/1841/205/7296/6241/158067/203/2936/4831/102157402/4833/7298/50484/204/2745/1854/2987/51727/26289/1503/6240/4830/122481/79077 28 Human_herpesvirus_1 R-HSA-418592 ADP signalling through P2Y purinoceptor 1 24/6371 25/10654 4.5842001829264976e-5 1.256871972483925e-4 4.834843728952627e-5 2788/2769/1432/2782/2776/2787/10681/2792/6714/2785/2783/2784/2791/2786/5321/54331/59345/51764/94235/55970/2767/2793/9630/2790 24 Human_herpesvirus_1 R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 24/6371 25/10654 4.5842001829264976e-5 1.256871972483925e-4 4.834843728952627e-5 51400/5520/8900/28227/5518/7465/5515/993/890/983/5519/7514/2305/9133/891/4331/5347/5516/1017/994/902/9088/995/1022 24 Human_herpesvirus_1 R-HSA-9006115 Signaling by NTRK2 (TRKB) 24/6371 25/10654 4.5842001829264976e-5 1.256871972483925e-4 4.834843728952627e-5 5295/627/4893/5335/2534/2885/3845/3265/5879/5290/6714/4909/5781/4908/6464/2904/7074/6654/2549/1020/4915/10817/10818/8851 24 Human_herpesvirus_1 R-HSA-112043 PLC beta mediated events 46/6371 54/10654 4.827300913655975e-5 1.3209590872252397e-4 5.0813693827957635e-5 5331/2770/817/5578/5582/107/814/2773/818/5567/5594/112/5573/111/5613/2771/5580/5153/196883/115/801/805/3838/2781/5568/113/10645/5566/84254/23236/816/5577/109/815/5321/5575/114/3708/108/2779/10768/346562/5576/1385/808/5137 46 Human_herpesvirus_1 R-HSA-9006936 Signaling by TGF-beta family members 80/6371 102/10654 4.895478855909148e-5 1.3370243993314734e-4 5.143168257455198e-5 10272/892/7321/4738/91851/130399/8239/9612/4609/4089/22938/23327/4088/5499/1030/9110/7040/10589/904/7314/5054/7027/11167/6497/51592/50848/7323/6667/4092/11171/7050/7046/92/94/5494/2280/9958/9040/6233/7514/1025/8928/57530/5500/4090/4221/4093/5590/9350/9765/269/3726/5501/1024/60436/8812/1874/142/905/4087/7048/7311/387/57154/9241/51377/10273/4086/64750/659/54778/7316/1875/9611/5933/867/3065/6498/657/56288 80 Human_herpesvirus_1 R-HSA-204005 COPII-mediated vesicle transport 56/6371 68/10654 5.5366613931566356e-5 1.5092212137330442e-4 5.805562444358512e-5 6811/23256/374/126003/2153/10484/7039/5861/9570/3998/9632/79090/10652/58485/10342/2801/22872/8615/55014/83696/27095/6399/7109/6396/1453/10959/2890/10802/2157/9554/966/11196/149111/10282/8775/81876/51693/23243/5537/9871/1075/9919/10113/51399/55291/122553/26984/63908/1522/22870/5265/8774/10972/4905/64689/10427 56 Human_herpesvirus_1 R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 19/6371 19/10654 5.6560080017447204e-5 1.5183048095938299e-4 5.840504560536874e-5 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Human_herpesvirus_1 R-HSA-163615 PKA activation 19/6371 19/10654 5.6560080017447204e-5 1.5183048095938299e-4 5.840504560536874e-5 107/5567/112/5573/111/196883/115/801/805/5568/113/5566/5577/109/5575/114/108/5576/808 19 Human_herpesvirus_1 R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 19/6371 19/10654 5.6560080017447204e-5 1.5183048095938299e-4 5.840504560536874e-5 11065/7321/8697/51529/29945/51434/29882/996/51433/119504/7324/64682/246184/8881/10393/51343/25906/991/8556 19 Human_herpesvirus_1 R-HSA-176412 Phosphorylation of the APC/C 19/6371 19/10654 5.6560080017447204e-5 1.5183048095938299e-4 5.840504560536874e-5 11065/7321/8697/51529/29945/51434/29882/996/983/51433/119504/7324/64682/246184/8881/891/10393/25906/5347 19 Human_herpesvirus_1 R-HSA-3928664 Ephrin signaling 19/6371 19/10654 5.6560080017447204e-5 1.5183048095938299e-4 5.840504560536874e-5 1947/2051/2050/2047/2534/1948/8440/8874/5062/5879/6714/1949/10627/2049/5063/6386/2048/5058/28964 19 Human_herpesvirus_1 R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 19/6371 19/10654 5.6560080017447204e-5 1.5183048095938299e-4 5.840504560536874e-5 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Human_herpesvirus_1 R-HSA-77595 Processing of Intronless Pre-mRNAs 19/6371 19/10654 5.6560080017447204e-5 1.5183048095938299e-4 5.840504560536874e-5 51585/81608/1477/53981/11051/8106/1478/23283/10914/10898/51692/22916/1479/79869/29894/4686/8189/10978/55339 19 Human_herpesvirus_1 R-HSA-8851708 Signaling by FGFR2 IIIa TM 19/6371 19/10654 5.6560080017447204e-5 1.5183048095938299e-4 5.840504560536874e-5 5431/5435/5433/5439/5438/2247/2246/2963/5434/5436/2263/2962/5432/22916/5440/5430/5441/4686/5437 19 Human_herpesvirus_1 R-HSA-2426168 Activation of gene expression by SREBF (SREBP) 37/6371 42/10654 5.840327515743344e-5 1.5618451614071217e-4 6.007992420501527e-5 79718/5469/1387/6907/4801/6309/10499/23054/85441/31/96764/4598/5465/2222/6667/3156/6604/10654/6319/6721/9453/4800/57678/32/1595/4047/4802/6720/2194/4597/1717/6256/10498/2224/3422/4520/8648 37 Human_herpesvirus_1 R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 37/6371 42/10654 5.840327515743344e-5 1.5618451614071217e-4 6.007992420501527e-5 83990/9156/1763/7486/5982/472/4683/84126/672/6117/83695/6118/5888/116028/7517/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/1111/79728/5983/5883/10111/675/545/10635/5932/7156 37 Human_herpesvirus_1 R-HSA-933541 TRAF6 mediated IRF7 activation 27/6371 29/10654 6.699871653064597e-5 1.7883211293246148e-4 6.879183709046528e-5 3443/80143/1387/64135/3445/29110/3444/23586/3451/3448/3661/3439/10010/84282/3452/3446/3665/7706/3440/7189/9641/3456/3441/7186/57506/3449/2033 27 Human_herpesvirus_1 R-HSA-203927 MicroRNA (miRNA) biogenesis 23/6371 24/10654 7.386633800607716e-5 1.9568343201609934e-4 7.527408000619298e-5 5431/5435/5433/5439/192669/29102/5438/54487/57510/8575/26523/23405/5434/5436/5901/5432/27161/6895/5440/5430/5441/192670/5437 23 Human_herpesvirus_1 R-HSA-3371571 HSF1-dependent transactivation 23/6371 24/10654 7.386633800607716e-5 1.9568343201609934e-4 7.527408000619298e-5 817/3305/1387/2475/3306/3312/818/3303/84335/3337/3297/57521/1410/64223/26353/816/3326/3304/10728/815/3320/2033/2288 23 Human_herpesvirus_1 R-HSA-5627123 RHO GTPases activate PAKs 23/6371 24/10654 7.386633800607716e-5 1.9568343201609934e-4 7.527408000619298e-5 2017/79784/4628/5062/5879/4638/4659/4771/801/5500/805/2316/10627/5063/998/5058/4629/3984/4627/10398/4637/103910/808 23 Human_herpesvirus_1 R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 23/6371 24/10654 7.386633800607716e-5 1.9568343201609934e-4 7.527408000619298e-5 374/7039/1839/5594/2069/10000/595/7514/2353/255324/5747/208/1956/5595/596/685/2309/207/6722/1027/1950/2002/1385 23 Human_herpesvirus_1 R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 30/6371 33/10654 8.042273167266638e-5 2.1225588247066342e-4 8.164904976506809e-5 4790/4792/177/3654/7334/3551/7314/257397/8767/23118/8517/5970/10454/6233/4791/351/387522/64127/3656/7189/7311/1147/6885/10392/7316/7335/4793/3146/6288/6285 30 Human_herpesvirus_1 R-HSA-5357905 Regulation of TNFR1 signaling 30/6371 33/10654 8.042273167266638e-5 2.1225588247066342e-4 8.164904976506809e-5 7124/25999/7375/10616/1540/3551/7314/90268/81858/8737/55072/841/8517/8887/7128/6233/331/8717/330/27005/8567/7311/1147/7186/56957/7316/7132/329/9099/7185 30 Human_herpesvirus_1 R-HSA-73887 Death Receptor Signalling 106/6371 141/10654 8.286665137289684e-5 2.1829796966143722e-4 8.397327593954197e-5 7124/25999/7984/4790/7531/29/356/7375/9530/8878/1894/23385/4792/8439/9138/836/23365/10616/57449/3654/6868/8997/26084/8874/1540/3551/7314/5879/257397/9181/90268/81858/8737/8767/55072/2245/23118/841/8517/8887/6453/9828/5970/8797/7128/396/10454/3066/6233/7410/7409/26574/8772/331/8717/8743/5663/84894/445328/572/27237/7074/330/10451/27005/50650/843/8837/11108/8567/7189/6654/4099/7311/387/6655/8795/5924/1147/4804/57142/8841/7186/56957/6885/5584/10018/57580/8793/835/9459/355/11214/23421/4615/9500/7316/9826/7132/329/9099/4803/3065/55512/5599/7185 106 Human_herpesvirus_1 R-HSA-5654221 Phospholipase C-mediated cascade; FGFR2 18/6371 18/10654 9.469117126799461e-5 2.4668622477935125e-4 9.489346353522086e-5 2250/5335/2252/2253/8823/8074/2249/2248/2247/2246/2251/2263/8822/8817/2254/26281/2255/27006 18 Human_herpesvirus_1 R-HSA-5654704 SHC-mediated cascade:FGFR3 18/6371 18/10654 9.469117126799461e-5 2.4668622477935125e-4 9.489346353522086e-5 4893/2250/2885/2253/3845/3265/8823/8074/2249/2247/2246/6464/6654/8822/8817/2254/26281/2261 18 Human_herpesvirus_1 R-HSA-5654710 PI-3K cascade:FGFR3 18/6371 18/10654 9.469117126799461e-5 2.4668622477935125e-4 9.489346353522086e-5 5295/2250/2885/2253/5290/8823/8074/2249/2247/2246/5781/2549/8822/8817/2254/26281/10818/2261 18 Human_herpesvirus_1 R-HSA-5675482 Regulation of necroptotic cell death 18/6371 18/10654 9.469117126799461e-5 2.4668622477935125e-4 9.489346353522086e-5 356/7314/8737/841/8797/6233/8772/331/8717/8743/330/8837/7311/8795/7186/355/7316/329 18 Human_herpesvirus_1 R-HSA-73780 RNA Polymerase III Chain Elongation 18/6371 18/10654 9.469117126799461e-5 2.4668622477935125e-4 9.489346353522086e-5 55718/5435/84265/10622/661/11128/9533/5434/10623/51728/171568/10621/5440/5441/51082/55703/27297/5437 18 Human_herpesvirus_1 R-HSA-8964315 G beta:gamma signalling through BTK 18/6371 18/10654 9.469117126799461e-5 2.4668622477935125e-4 9.489346353522086e-5 2788/2782/2787/10681/2792/2785/2783/2784/2791/695/2786/54331/59345/51764/94235/55970/2793/2790 18 Human_herpesvirus_1 R-HSA-202040 G-protein activation 26/6371 28/10654 1.048728023808967e-4 2.7170715038867183e-4 1.0451833129607475e-4 2788/2770/4988/2782/2773/2787/10681/5443/2792/2785/2783/2784/2771/2791/2781/2786/54331/59345/51764/94235/2779/5173/55970/346562/2793/2790 26 Human_herpesvirus_1 R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 26/6371 28/10654 1.048728023808967e-4 2.7170715038867183e-4 1.0451833129607475e-4 10381/10576/7846/7411/81027/10574/10693/5201/5204/10575/10471/5202/84617/10382/7277/347733/10383/60/84790/22948/7280/10694/5203/7203/908/6950 26 Human_herpesvirus_1 R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 26/6371 28/10654 1.048728023808967e-4 2.7170715038867183e-4 1.0451833129607475e-4 2788/2770/2782/2787/10681/112/111/2792/2785/2783/2784/2771/2791/9254/150/775/2786/54331/59345/776/51764/94235/55970/152/2793/2790 26 Human_herpesvirus_1 R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 41/6371 48/10654 1.1104403810626065e-4 2.8716883114659347e-4 1.1046601824335936e-4 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/8812/905/2071/5432/22916/6917/5440/902/5430/6749/5441/7469/4686/9150/5437/6827/2968/1022/8178 41 Human_herpesvirus_1 R-HSA-112409 RAF-independent MAPK1/3 activation 22/6371 23/10654 1.1883188344544306e-4 3.050738534999375e-4 1.1735359207243754e-4 1844/1850/1848/1852/5605/3717/1847/3569/3572/1849/5594/983/80824/1843/3570/7297/5781/1846/11221/3716/5595/5604 22 Human_herpesvirus_1 R-HSA-438066 Unblocking of NMDA receptors, glutamate binding and activation 22/6371 23/10654 1.1883188344544306e-4 3.050738534999375e-4 1.1735359207243754e-4 817/1741/1739/1740/818/2892/2902/2906/801/2891/4747/805/2904/2890/2905/816/2893/815/2903/1742/88/808 22 Human_herpesvirus_1 R-HSA-73980 RNA Polymerase III Transcription Termination 22/6371 23/10654 1.1883188344544306e-4 3.050738534999375e-4 1.1735359207243754e-4 55718/4774/5435/84265/10622/661/11128/9533/5434/10623/51728/171568/10621/4784/5440/5441/51082/55703/27297/5437/4782/6741 22 Human_herpesvirus_1 R-HSA-9617324 Negative regulation of NMDA receptor-mediated neuronal transmission 22/6371 23/10654 1.1883188344544306e-4 3.050738534999375e-4 1.1735359207243754e-4 817/1741/1739/1740/814/818/2902/22843/2906/801/4747/805/2904/2905/816/815/2903/9647/1742/88/808/8536 22 Human_herpesvirus_1 R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 29/6371 32/10654 1.230605365458497e-4 3.1364887653924145e-4 1.2065216959463888e-4 892/4609/4089/22938/4088/1030/904/7314/5054/7027/6667/4092/7050/6233/1025/4221/3726/1024/60436/8812/1874/905/4087/7311/54778/7316/1875/5933/3065 29 Human_herpesvirus_1 R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 29/6371 32/10654 1.230605365458497e-4 3.1364887653924145e-4 1.2065216959463888e-4 51807/10381/10576/7846/7411/81027/10574/10693/5201/5204/10575/10471/10376/5202/84617/10382/7277/347733/10383/60/84790/22948/7280/10694/5203/112714/7203/908/6950 29 Human_herpesvirus_1 R-HSA-392518 Signal amplification 29/6371 32/10654 1.230605365458497e-4 3.1364887653924145e-4 1.2065216959463888e-4 2788/64805/2770/2769/1432/2782/2776/2773/2787/10681/2792/6714/2785/2783/2784/2771/2791/2786/5321/54331/59345/51764/94235/55970/2767/346562/2793/9630/2790 29 Human_herpesvirus_1 R-HSA-5626467 RHO GTPases activate IQGAPs 29/6371 32/10654 1.230605365458497e-4 3.1364887653924145e-4 1.2065216959463888e-4 71/6249/51807/347688/10381/7846/81027/8826/5879/999/10376/128239/801/4221/805/84617/10382/7277/347733/998/10788/10383/60/84790/7280/1495/1499/112714/808 29 Human_herpesvirus_1 R-HSA-112040 G-protein mediated events 46/6371 55/10654 1.237979217301261e-4 3.1495975762691543e-4 1.2115642980131828e-4 5331/2770/817/5578/5582/107/814/2773/818/5567/5594/112/5573/111/5613/2771/5580/5153/196883/115/801/805/3838/2781/5568/113/10645/5566/84254/23236/816/5577/109/815/5321/5575/114/3708/108/2779/10768/346562/5576/1385/808/5137 46 Human_herpesvirus_1 R-HSA-194315 Signaling by Rho GTPases 309/6371 455/10654 1.5837985253006943e-4 3.9406494083632916e-4 1.5158603658233625e-4 55839/11130/7984/398/64837/71/6249/51517/5579/57522/392/9735/7531/55789/5526/29/51807/2909/10971/5578/9212/347688/613/3798/1894/388/7533/2810/147841/348995/54509/10381/57122/6280/1780/23122/3688/5048/57405/8655/10094/23279/5881/1432/2017/2491/9138/7846/23365/79784/9475/1060/171177/9322/397/81027/4628/57449/51291/11004/8976/1855/2885/23433/6093/9184/8997/8826/10499/5518/26084/8874/23332/25909/10726/81930/5062/55746/9411/2665/5879/5515/9181/85415/25/79682/1072/10403/4638/25936/4659/10093/1856/10006/4771/2245/389/5594/29127/3619/64105/89839/1124/7534/94274/332/5528/6453/9828/6714/79902/3796/5519/81565/999/89953/396/10810/5880/85360/91687/11243/10376/57584/11113/58504/83540/7410/5580/7409/1857/128239/9055/4649/7514/23191/147700/54820/29984/1729/6396/1535/5600/91614/801/64946/9793/30849/10109/5586/140735/9886/2664/5500/4221/805/3831/220134/5170/84617/4928/4688/9743/445328/5590/5903/9912/653361/55055/5747/80776/1783/401541/64411/2316/7532/3633/27237/10382/7074/10627/79172/7277/10451/79980/58480/6232/5501/50650/10152/6279/55288/54821/10092/9183/4650/10163/1062/699/94134/752/347733/22919/55845/5063/3895/57514/5529/51143/998/695/10788/354/6654/10097/57120/367/57381/10383/5347/387/6655/60/84790/84643/5058/5924/7280/4629/7529/5595/64130/1778/5516/5905/81929/3984/27035/54908/55143/1495/1499/5525/4690/1058/991/79019/57580/4627/10928/348235/80152/10458/1063/3985/6722/8379/1027/9459/11214/1080/23421/55920/79023/112714/6242/1781/9824/10398/4085/5289/5585/5216/10552/81624/55166/9826/23092/4637/1123/51466/995/79003/391/23221/23028/89941/2/1742/90627/5527/4689/10096/7454/701/23380/9928/29941/3799/103910/57551/5296/5300/808/10095/1536/399/4952/9901 309 Human_herpesvirus_1 R-HSA-164378 PKA activation in glucagon signalling 17/6371 17/10654 1.5851904135625705e-4 3.9406494083632916e-4 1.5158603658233625e-4 107/5567/112/5573/111/196883/115/5568/113/5566/5577/109/5575/114/108/2778/5576 17 Human_herpesvirus_1 R-HSA-180292 GAB1 signalosome 17/6371 17/10654 1.5851904135625705e-4 3.9406494083632916e-4 1.5158603658233625e-4 5295/374/7039/55824/2885/5829/1839/5290/2069/6714/1445/255324/5781/1956/2549/685/1950 17 Human_herpesvirus_1 R-HSA-196299 Beta-catenin phosphorylation cascade 17/6371 17/10654 1.5851904135625705e-4 3.9406494083632916e-4 1.5158603658233625e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/10023/23401/5529/5516/1499/5525/139285/5527 17 Human_herpesvirus_1 R-HSA-2033519 Activated point mutants of FGFR2 17/6371 17/10654 1.5851904135625705e-4 3.9406494083632916e-4 1.5158603658233625e-4 2250/2252/2253/8823/8074/2249/2248/2247/2246/2251/2263/8822/8817/2254/26281/2255/27006 17 Human_herpesvirus_1 R-HSA-416993 Trafficking of GluR2-containing AMPA receptors 17/6371 17/10654 1.5851904135625705e-4 3.9406494083632916e-4 1.5158603658233625e-4 5579/23426/5578/5582/9463/163/161/2892/1175/2891/7102/1173/2890/160/80852/2893/4905 17 Human_herpesvirus_1 R-HSA-432142 Platelet sensitization by LDL 17/6371 17/10654 1.5851904135625705e-4 3.9406494083632916e-4 1.5158603658233625e-4 5777/5526/5175/2268/1432/5518/5515/5528/5519/5781/338/5529/5516/5321/5525/5527/7804 17 Human_herpesvirus_1 R-HSA-450385 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA 17/6371 17/10654 1.5851904135625705e-4 3.9406494083632916e-4 1.5158603658233625e-4 5393/23404/11340/9261/23016/118460/677/51010/56915/167227/7529/22894/207/55802/51013/54464/54512 17 Human_herpesvirus_1 R-HSA-450513 Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA 17/6371 17/10654 1.5851904135625705e-4 3.9406494083632916e-4 1.5158603658233625e-4 5393/23404/11340/9261/23016/118460/3842/7538/51010/56915/167227/7529/22894/55802/51013/54464/54512 17 Human_herpesvirus_1 R-HSA-450604 KSRP (KHSRP) binds and destabilizes mRNA 17/6371 17/10654 1.5851904135625705e-4 3.9406494083632916e-4 1.5158603658233625e-4 5393/23404/1432/11340/7534/5600/8570/23016/118460/5073/51010/56915/167227/22894/207/51013/54512 17 Human_herpesvirus_1 R-HSA-5655862 Translesion synthesis by POLK 17/6371 17/10654 1.5851904135625705e-4 3.9406494083632916e-4 1.5158603658233625e-4 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/51426/7311/5983/7316/10459/5981/5980 17 Human_herpesvirus_1 R-HSA-5656121 Translesion synthesis by POLI 17/6371 17/10654 1.5851904135625705e-4 3.9406494083632916e-4 1.5158603658233625e-4 5982/6117/7314/6118/11201/51455/5985/5984/6233/5111/6119/7311/5983/7316/10459/5981/5980 17 Human_herpesvirus_1 R-HSA-8934593 Regulation of RUNX1 Expression and Activity 17/6371 17/10654 1.5851904135625705e-4 3.9406494083632916e-4 1.5158603658233625e-4 27327/192669/5371/4343/865/6714/595/896/26523/5781/27161/894/57690/192670/1021/861/23112 17 Human_herpesvirus_1 R-HSA-1368108 BMAL1:CLOCK,NPAS2 activates circadian gene expression 25/6371 27/10654 1.6376085865010853e-4 4.035433375461662e-4 1.5523211732057686e-4 79718/28999/5469/1628/1387/6907/2155/10499/23054/9575/85441/96764/5054/10135/5465/6604/56938/406/8553/4862/79365/6256/10498/8648/551 25 Human_herpesvirus_1 R-HSA-164952 The role of Nef in HIV-1 replication and disease pathogenesis 25/6371 27/10654 1.6376085865010853e-4 4.035433375461662e-4 1.5523211732057686e-4 162/1174/567/2534/163/55690/5062/5879/51606/161/10053/926/3932/1175/8907/940/1173/160/920/8905/164/919/130340/3055/375 25 Human_herpesvirus_1 R-HSA-354192 Integrin alphaIIb beta3 signaling 25/6371 27/10654 1.6376085865010853e-4 4.035433375461662e-4 1.5523211732057686e-4 5770/5908/2244/3690/2885/9564/7094/10125/6714/2335/1445/2266/2243/5170/6464/5747/3674/6850/6654/7450/207/54518/1398/10235/5906 25 Human_herpesvirus_1 R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 25/6371 27/10654 1.6376085865010853e-4 4.035433375461662e-4 1.5523211732057686e-4 356/836/929/26060/219699/1612/8737/841/8797/1613/8772/8717/8743/8837/8795/23643/7186/842/355/7099/9500/23604/1630/353376/148022 25 Human_herpesvirus_1 R-HSA-9006921 Integrin signaling 25/6371 27/10654 1.6376085865010853e-4 4.035433375461662e-4 1.5523211732057686e-4 5770/5908/2244/3690/2885/9564/7094/10125/6714/2335/1445/2266/2243/5170/6464/5747/3674/6850/6654/7450/207/54518/1398/10235/5906 25 Human_herpesvirus_1 R-HSA-399719 Trafficking of AMPA receptors 28/6371 31/10654 1.877680100280619e-4 4.6109292201673637e-4 1.773698730882928e-4 5579/23426/817/5578/5582/9463/9495/1739/163/818/161/4646/2892/1175/2891/7102/1173/2890/2036/160/80852/816/10369/2893/815/4905/1742/4193 28 Human_herpesvirus_1 R-HSA-399721 Glutamate binding, activation of AMPA receptors and synaptic plasticity 28/6371 31/10654 1.877680100280619e-4 4.6109292201673637e-4 1.773698730882928e-4 5579/23426/817/5578/5582/9463/9495/1739/163/818/161/4646/2892/1175/2891/7102/1173/2890/2036/160/80852/816/10369/2893/815/4905/1742/4193 28 Human_herpesvirus_1 R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 34/6371 39/10654 1.8931128864859334e-4 4.637944815921639e-4 1.7840908938538584e-4 83990/9156/1763/7486/5982/472/4683/84126/672/6117/83695/6118/5888/116028/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/1111/5983/5883/10111/675/545/5932/7156 34 Human_herpesvirus_1 R-HSA-113510 E2F mediated regulation of DNA replication 21/6371 22/10654 1.9083894745399946e-4 4.637944815921639e-4 1.7840908938538584e-4 5925/5422/1869/84515/4998/28227/5518/5001/5558/5515/23594/7027/5557/983/5519/23649/4999/5000/891/23595/5516 21 Human_herpesvirus_1 R-HSA-389357 CD28 dependent PI3K/Akt signaling 21/6371 22/10654 1.9083894745399946e-4 4.637944815921639e-4 1.7840908938538584e-4 5295/941/2534/2475/1326/5290/57761/9020/10000/3932/940/253260/5170/64223/8503/208/79109/207/55615/942/5296 21 Human_herpesvirus_1 R-HSA-442982 Ras activation upon Ca2+ influx through NMDA receptor 21/6371 22/10654 1.9083894745399946e-4 4.637944815921639e-4 1.7840908938538584e-4 4893/817/1741/1739/1740/3845/3265/5923/818/2902/2906/801/4747/805/2904/816/5924/815/1742/88/808 21 Human_herpesvirus_1 R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 21/6371 22/10654 1.9083894745399946e-4 4.637944815921639e-4 1.7840908938538584e-4 3725/7531/356/7001/4001/826/823/2801/993/351/6648/1020/4000/994/2309/10018/831/824/995/8851/5052 21 Human_herpesvirus_1 R-HSA-8863678 Neurodegenerative Diseases 21/6371 22/10654 1.9083894745399946e-4 4.637944815921639e-4 1.7840908938538584e-4 3725/7531/356/7001/4001/826/823/2801/993/351/6648/1020/4000/994/2309/10018/831/824/995/8851/5052 21 Human_herpesvirus_1 R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 31/6371 35/10654 1.9455173773835226e-4 4.7200524688411233e-4 1.8156754688549427e-4 23165/91754/348995/57122/23511/23279/23225/9972/8021/55746/10762/983/79902/9883/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/81929/9631/79023/23636/53371/9688/8480 31 Human_herpesvirus_1 R-HSA-167169 HIV Transcription Elongation 39/6371 46/10654 2.2990199119207408e-4 5.543792296696417e-4 2.1325457172322585e-4 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/7469/4686/9150/5437/6827/2968/1022/8178 39 Human_herpesvirus_1 R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 39/6371 46/10654 2.2990199119207408e-4 5.543792296696417e-4 2.1325457172322585e-4 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/7469/4686/9150/5437/6827/2968/1022/8178 39 Human_herpesvirus_1 R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 39/6371 46/10654 2.2990199119207408e-4 5.543792296696417e-4 2.1325457172322585e-4 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/7469/4686/9150/5437/6827/2968/1022/8178 39 Human_herpesvirus_1 R-HSA-5619084 ABC transporter disorders 61/6371 77/10654 2.3007523270992213e-4 5.543792296696417e-4 2.1325457172322585e-4 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/51009/5696/5691/7314/5718/5700/122706/5707/10956/79139/91445/23198/9861/5698/5692/5713/5710/5719/6233/27248/6048/5706/19/335/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/1244/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 61 Human_herpesvirus_1 R-HSA-912694 Regulation of IFNA signaling 24/6371 26/10654 2.5505557560196617e-4 6.135238036626512e-4 2.3600587646483375e-4 3443/5777/5770/9021/11274/3445/3444/3451/3448/3439/3452/6773/7297/5781/3446/3455/6772/8651/3440/3454/3716/3456/3441/3449 24 Human_herpesvirus_1 R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 36/6371 42/10654 2.5648101331719774e-4 6.159033857208898e-4 2.3692123679139643e-4 2788/1459/2770/1460/10576/1457/2782/10574/10693/2773/2787/10575/10681/2792/2785/2783/2784/2771/2791/2781/5082/2786/22948/10694/54331/59345/51764/94235/2779/7203/908/55970/346562/2793/6950/2790 36 Human_herpesvirus_1 R-HSA-110312 Translesion synthesis by REV1 16/6371 16/10654 2.6535414035371534e-4 6.265552611696423e-4 2.410187227997133e-4 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/7311/5983/7316/10459/5981/5980 16 Human_herpesvirus_1 R-HSA-1295596 Spry regulation of FGF signaling 16/6371 16/10654 2.6535414035371534e-4 6.265552611696423e-4 2.410187227997133e-4 8569/2885/5518/7314/5515/5594/6714/6233/5781/673/7311/5595/5516/10253/7316/867 16 Human_herpesvirus_1 R-HSA-1433559 Regulation of KIT signaling 16/6371 16/10654 2.6535414035371534e-4 6.265552611696423e-4 2.410187227997133e-4 5777/5578/2534/2885/10603/3815/9306/6714/7525/3932/10019/8651/4067/6654/867/4254 16 Human_herpesvirus_1 R-HSA-156711 Polo-like kinase mediated events 16/6371 16/10654 2.6535414035371534e-4 6.265552611696423e-4 2.410187227997133e-4 5928/7465/993/2305/9133/286826/891/91750/55957/5347/4605/1063/9088/2033/995/132660 16 Human_herpesvirus_1 R-HSA-193639 p75NTR signals via NF-kB 16/6371 16/10654 2.6535414035371534e-4 6.265552611696423e-4 2.410187227997133e-4 4790/8878/4792/3654/3551/7314/8767/5970/6233/7189/7311/4804/5584/4615/7316/4803 16 Human_herpesvirus_1 R-HSA-1963640 GRB2 events in ERBB2 signaling 16/6371 16/10654 2.6535414035371534e-4 6.265552611696423e-4 2.410187227997133e-4 4893/2064/145957/9542/2885/3845/3265/1839/2069/3084/6654/10718/1956/685/1950/2066 16 Human_herpesvirus_1 R-HSA-1963642 PI3K events in ERBB2 signaling 16/6371 16/10654 2.6535414035371534e-4 6.265552611696423e-4 2.410187227997133e-4 5295/2064/145957/9542/2885/1839/5290/2065/2069/3084/10718/1956/2549/685/1950/2066 16 Human_herpesvirus_1 R-HSA-5654219 Phospholipase C-mediated cascade: FGFR1 16/6371 16/10654 2.6535414035371534e-4 6.265552611696423e-4 2.410187227997133e-4 2250/5335/2253/8074/2260/2249/2248/2247/2246/2251/9365/8822/2254/26281/2255/27006 16 Human_herpesvirus_1 R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 16/6371 16/10654 2.6535414035371534e-4 6.265552611696423e-4 2.410187227997133e-4 8454/4790/3551/7314/8945/1326/8517/6233/79155/7311/6416/1147/5604/6500/7316/23291 16 Human_herpesvirus_1 R-HSA-9614657 FOXO-mediated transcription of cell death genes 16/6371 16/10654 2.6535414035371534e-4 6.265552611696423e-4 2.410187227997133e-4 2308/65018/356/1387/4801/604/4303/4800/10370/6794/27113/2309/10018/4802/1649/2033 16 Human_herpesvirus_1 R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 33/6371 38/10654 2.783676138854897e-4 6.561854270556118e-4 2.524166396009361e-4 5908/3313/6175/3936/5898/3181/4001/4282/5062/1072/6627/9049/27250/9987/3185/3458/5478/302/552900/6775/9446/4478/998/6648/2939/6888/3586/829/6647/6950/4507/375/5721 33 Human_herpesvirus_1 R-HSA-2424491 DAP12 signaling 27/6371 30/10654 2.856346747071255e-4 6.710751425731468e-4 2.581443071177455e-4 5295/4893/5335/7305/5291/3824/567/2534/2885/3133/3845/3265/5879/5290/5336/7410/3932/6464/3937/10451/6850/22914/695/6654/9402/27040/5296 27 Human_herpesvirus_1 R-HSA-6804758 Regulation of TP53 Activity through Acetylation 27/6371 30/10654 2.856346747071255e-4 6.710751425731468e-4 2.581443071177455e-4 64769/84289/29117/5928/1107/5371/23774/3622/27154/57459/10000/7994/3066/7157/5608/7862/9219/5931/1108/54815/208/53615/5305/207/2033/3065/5300 27 Human_herpesvirus_1 R-HSA-445144 Signal transduction by L1 20/6371 21/10654 3.0590430004928383e-4 7.151272709761404e-4 2.7508995961211303e-4 1459/1460/4684/3688/1457/5605/3690/5879/5594/2260/7410/3685/3674/3678/3897/1956/5058/5595/5604/3680 20 Human_herpesvirus_1 R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 20/6371 21/10654 3.0590430004928383e-4 7.151272709761404e-4 2.7508995961211303e-4 2237/5982/6117/10714/6118/328/3978/5985/5984/5424/54107/5425/5111/6119/5427/5983/56655/57804/5426/5981 20 Human_herpesvirus_1 R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 20/6371 21/10654 3.0590430004928383e-4 7.151272709761404e-4 2.7508995961211303e-4 25904/55571/55835/57472/85456/29883/1263/7832/10769/7157/5325/4869/4850/246175/4848/23019/4849/9337/28984/995 20 Human_herpesvirus_1 R-HSA-6790901 rRNA modification in the nucleus and cytosol 50/6371 62/10654 3.8199817217905e-4 8.915395357302788e-4 3.429509470976769e-4 55226/10528/84135/27340/88745/51096/55272/51077/23160/10607/11103/6208/22984/10813/9136/6203/51504/54433/27292/56902/51602/54555/10171/5822/2091/55651/55127/6194/10436/9277/84128/4839/134430/92856/65083/115939/11056/9790/55505/51202/6187/79050/55813/25879/57050/1736/10199/25926/6201/10885 50 Human_herpesvirus_1 R-HSA-8854691 Interleukin-20 family signaling 23/6371 25/10654 3.961462040394159e-4 9.199974343810118e-4 3.5389792466125104e-4 11009/6776/3717/282618/50604/3588/55801/3718/6777/6773/7297/5781/6775/50616/53833/6774/6772/29949/116379/163702/3716/58985/53832 23 Human_herpesvirus_1 R-HSA-937041 IKK complex recruitment mediated by RIP1 23/6371 25/10654 3.961462040394159e-4 9.199974343810118e-4 3.5389792466125104e-4 7321/929/7334/3551/7314/11035/8737/8517/7323/6233/387522/330/7189/7311/23643/1147/7099/7316/7335/7322/329/353376/148022 23 Human_herpesvirus_1 R-HSA-9620244 Long-term potentiation 23/6371 25/10654 3.961462040394159e-4 9.199974343810118e-4 3.5389792466125104e-4 817/1741/1739/1740/818/2902/6714/2906/801/2891/4747/805/2904/2890/2905/3084/816/815/2903/2066/1742/88/808 23 Human_herpesvirus_1 R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK 26/6371 29/10654 4.331148797497328e-4 9.907721159847784e-4 3.81123014647492e-4 5563/53632/10325/2475/10670/92335/64121/51422/7249/5494/57521/28956/389541/58528/64223/5571/6794/6009/55004/5562/5564/5565/7248/153129/8649/10542 26 Human_herpesvirus_1 R-HSA-9619483 Activation of AMPK downstream of NMDARs 26/6371 29/10654 4.331148797497328e-4 9.907721159847784e-4 3.81123014647492e-4 5563/51807/347688/53632/10381/7846/81027/51422/10376/801/805/84617/10382/7277/10645/5571/347733/5562/10383/84790/5564/5565/7280/112714/4137/808 26 Human_herpesvirus_1 R-HSA-422356 Regulation of insulin secretion 61/6371 78/10654 4.413382121309234e-4 9.907721159847784e-4 3.81123014647492e-4 2788/5331/2740/2770/5578/2769/9495/2782/3630/2776/8826/777/2181/6513/2787/5567/1131/10681/112/5573/111/2792/2785/2783/2784/2771/6844/2182/2791/9254/5568/150/6616/5566/775/23236/2641/6514/2786/5577/773/54331/5575/59345/776/51764/94235/114/3708/4082/55970/2778/2767/10768/152/2793/5576/948/5906/9630/2790 61 Human_herpesvirus_1 R-HSA-111447 Activation of BAD and translocation to mitochondria 15/6371 15/10654 4.441634202679638e-4 9.907721159847784e-4 3.81123014647492e-4 7531/10971/7533/2810/637/7534/10000/572/7532/208/7529/5533/596/207/5534 15 Human_herpesvirus_1 R-HSA-1170546 Prolactin receptor signaling 15/6371 15/10654 4.441634202679638e-4 9.907721159847784e-4 3.81123014647492e-4 8454/6776/9978/3717/5618/8945/2690/5617/6777/5781/1442/2689/6500/25970/2688 15 Human_herpesvirus_1 R-HSA-354194 GRB2:SOS provides linkage to MAPK signaling for Integrins 15/6371 15/10654 4.441634202679638e-4 9.907721159847784e-4 3.81123014647492e-4 5908/2244/3690/2885/7094/6714/2335/2266/2243/5747/3674/6654/7450/54518/5906 15 Human_herpesvirus_1 R-HSA-372708 p130Cas linkage to MAPK signaling for integrins 15/6371 15/10654 4.441634202679638e-4 9.907721159847784e-4 3.81123014647492e-4 5908/2244/3690/9564/7094/6714/2335/2266/2243/5747/3674/7450/54518/1398/5906 15 Human_herpesvirus_1 R-HSA-430039 mRNA decay by 5' to 3' exoribonuclease 15/6371 15/10654 4.441634202679638e-4 9.907721159847784e-4 3.81123014647492e-4 80153/219988/51690/11157/23644/27258/57819/23658/167227/1656/27257/25804/55802/196513/54464 15 Human_herpesvirus_1 R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 15/6371 15/10654 4.441634202679638e-4 9.907721159847784e-4 3.81123014647492e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Human_herpesvirus_1 R-HSA-5099900 WNT5A-dependent internalization of FZD4 15/6371 15/10654 4.441634202679638e-4 9.907721159847784e-4 3.81123014647492e-4 5579/5578/1212/5582/163/161/1856/8322/7474/1213/1211/1175/1173/409/160 15 Human_herpesvirus_1 R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 15/6371 15/10654 4.441634202679638e-4 9.907721159847784e-4 3.81123014647492e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Human_herpesvirus_1 R-HSA-5358508 Mismatch Repair 15/6371 15/10654 4.441634202679638e-4 9.907721159847784e-4 3.81123014647492e-4 4436/9156/6117/10714/4437/6118/3978/5424/2956/4292/5425/5111/6119/57804/5395 15 Human_herpesvirus_1 R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 15/6371 15/10654 4.441634202679638e-4 9.907721159847784e-4 3.81123014647492e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Human_herpesvirus_1 R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 15/6371 15/10654 4.441634202679638e-4 9.907721159847784e-4 3.81123014647492e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Human_herpesvirus_1 R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 15/6371 15/10654 4.441634202679638e-4 9.907721159847784e-4 3.81123014647492e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Human_herpesvirus_1 R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 15/6371 15/10654 4.441634202679638e-4 9.907721159847784e-4 3.81123014647492e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Human_herpesvirus_1 R-HSA-5637810 Constitutive Signaling by EGFRvIII 15/6371 15/10654 4.441634202679638e-4 9.907721159847784e-4 3.81123014647492e-4 5295/4893/5335/2885/3845/3265/5290/6464/6654/1956/2549/11140/1950/867/3320 15 Human_herpesvirus_1 R-HSA-5637812 Signaling by EGFRvIII in Cancer 15/6371 15/10654 4.441634202679638e-4 9.907721159847784e-4 3.81123014647492e-4 5295/4893/5335/2885/3845/3265/5290/6464/6654/1956/2549/11140/1950/867/3320 15 Human_herpesvirus_1 R-HSA-5654228 Phospholipase C-mediated cascade; FGFR4 15/6371 15/10654 4.441634202679638e-4 9.907721159847784e-4 3.81123014647492e-4 5335/9965/2264/2253/8823/8074/2249/2247/2246/2251/8822/8817/2254/152831/26281 15 Human_herpesvirus_1 R-HSA-6785631 ERBB2 Regulates Cell Motility 15/6371 15/10654 4.441634202679638e-4 9.907721159847784e-4 3.81123014647492e-4 2064/145957/9542/1839/2065/2069/1729/3084/10718/387/1956/685/1950/51072/2066 15 Human_herpesvirus_1 R-HSA-69183 Processive synthesis on the lagging strand 15/6371 15/10654 4.441634202679638e-4 9.907721159847784e-4 3.81123014647492e-4 2237/1763/5422/6117/10714/5558/6118/3978/5557/23649/5424/5425/5111/6119/57804 15 Human_herpesvirus_1 R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 15/6371 15/10654 4.441634202679638e-4 9.907721159847784e-4 3.81123014647492e-4 6456/30011/2885/7314/8027/2060/9146/6455/6233/4233/7311/7316/867/10254/6457 15 Human_herpesvirus_1 R-HSA-937039 IRAK1 recruits IKK complex 15/6371 15/10654 4.441634202679638e-4 9.907721159847784e-4 3.81123014647492e-4 3654/7334/3551/7314/8517/6233/387522/57162/7189/7311/1147/246330/7316/7335/57161 15 Human_herpesvirus_1 R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 15/6371 15/10654 4.441634202679638e-4 9.907721159847784e-4 3.81123014647492e-4 3654/51135/7334/7314/54106/6233/51311/3665/387522/7189/7311/51284/4615/7316/7335 15 Human_herpesvirus_1 R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 15/6371 15/10654 4.441634202679638e-4 9.907721159847784e-4 3.81123014647492e-4 3654/7334/3551/7314/8517/6233/387522/57162/7189/7311/1147/246330/7316/7335/57161 15 Human_herpesvirus_1 R-HSA-418217 G beta:gamma signalling through PLC beta 19/6371 20/10654 4.89347069352643e-4 0.0010830063666550655 4.16603015650823e-4 2788/5331/2782/2787/10681/2792/2785/2783/2784/2791/23236/2786/54331/59345/51764/94235/55970/2793/2790 19 Human_herpesvirus_1 R-HSA-5625900 RHO GTPases activate CIT 19/6371 20/10654 4.89347069352643e-4 0.0010830063666550655 4.16603015650823e-4 388/79784/4628/5879/4659/389/11113/9055/5500/10627/387/4629/4627/1027/10398/4637/1742/9928/103910 19 Human_herpesvirus_1 R-HSA-5627117 RHO GTPases Activate ROCKs 19/6371 20/10654 4.89347069352643e-4 0.0010830063666550655 4.16603015650823e-4 388/79784/9475/4628/6093/1072/4659/389/5500/10627/387/5058/4629/3984/4627/3985/10398/4637/103910 19 Human_herpesvirus_1 R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 19/6371 20/10654 4.89347069352643e-4 0.0010830063666550655 4.16603015650823e-4 472/1387/51499/7159/637/27166/23368/7157/63970/55240/5366/84883/147923/94241/8626/7161/665/27113/581 19 Human_herpesvirus_1 R-HSA-8876384 Listeria monocytogenes entry into host cells 19/6371 20/10654 4.89347069352643e-4 0.0010830063666550655 4.16603015650823e-4 6456/30011/2885/7314/8027/2060/1500/6714/999/9146/6455/6233/4233/7311/1499/7316/867/10254/6457 19 Human_herpesvirus_1 R-HSA-9609507 Protein localization 118/6371 163/10654 4.982300834715915e-4 0.0011009403409419204 4.2350172649920304e-4 6811/9218/26063/7321/131118/10965/10901/5621/1384/23600/3313/10005/8239/10440/50/7917/819/3417/390916/51142/25813/4358/80273/3421/5192/7314/1891/54677/10952/26061/51608/8528/847/7323/54927/3329/100287932/2053/10469/8604/8799/8309/10455/5189/2010/196743/8540/11001/6233/6844/1610/9804/83752/55670/373156/5264/189/3155/10531/5193/30/351/122970/51/55825/91452/8266/7416/293/1678/150274/1962/118424/4580/54363/5830/10651/51179/54469/7311/6342/84896/5195/29928/401505/6449/3295/10063/51268/8310/10452/5824/7316/10165/7322/56993/3416/5825/26521/4843/26517/6901/5190/92609/617/54543/5828/27230/283927/224/1537/219743/570/3162/5194/5191/8443/291 118 Human_herpesvirus_1 R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 28/6371 32/10654 6.40720324403553e-4 0.0014135892157153386 5.437692226845943e-4 5295/5777/84876/2534/30011/2885/973/6786/80228/5336/7409/118788/801/805/930/6850/4067/29760/695/6654/5293/27071/4690/640/3708/10768/974/808 28 Human_herpesvirus_1 R-HSA-8878171 Transcriptional regulation by RUNX1 167/6371 239/10654 6.987558390777523e-4 0.0015392250308545806 5.920978946779212e-4 1912/9070/5689/1437/5579/5682/1459/6045/9021/5929/27327/80012/1460/143471/5705/5709/5695/28996/1457/1911/6603/10413/5711/1387/3558/5683/10138/57332/5699/8312/5702/192669/83737/5371/57492/6688/4343/5696/5691/7314/55170/5718/84661/25/4773/8861/196528/5700/122706/5707/23198/86/100506658/865/7082/23309/51412/6714/2099/9861/8850/84733/5588/6604/8289/5698/5692/5713/6602/595/5710/3458/1998/896/5719/23067/6233/161882/26523/5781/1493/23429/55193/6015/55904/6595/3562/6597/6929/8535/3674/1378/6938/3958/5706/6599/200845/4331/57678/2623/5714/5688/5687/5708/6886/4602/5704/7311/7161/860/58508/25942/648/5694/6601/23466/4297/4004/27161/894/5684/5720/902/2624/11091/640/8085/5690/2625/57690/5717/9491/4005/6598/10197/192670/5196/7316/10213/5079/10398/122809/5715/5701/5685/5686/2033/1021/84333/6605/50943/3065/861/23112/9757/5716/2811/9739/8784/3276/3977/3559/7057/1022/5693/5721/1997 167 Human_herpesvirus_1 R-HSA-1250347 SHC1 events in ERBB4 signaling 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 4893/145957/9542/2885/3845/3265/1839/2069/6464/3084/6654/10718/685/2066 14 Human_herpesvirus_1 R-HSA-162594 Early Phase of HIV Life Cycle 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 2237/7852/3981/3836/7518/3978/11168/5478/920/2547/1234/3159/7520/8815 14 Human_herpesvirus_1 R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 5861/2801/5594/983/8548/8615/9133/891/81876/5347/5595/5862/26003/64689 14 Human_herpesvirus_1 R-HSA-169893 Prolonged ERK activation events 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 5605/1399/5594/4914/673/2889/7529/5595/5604/57498/10818/4803/1398/5906 14 Human_herpesvirus_1 R-HSA-174411 Polymerase switching on the C-strand of the telomere 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 5982/5422/10714/5558/5557/5985/5984/23649/5424/5425/5111/5983/57804/5981 14 Human_herpesvirus_1 R-HSA-180336 SHC1 events in EGFR signaling 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 374/4893/7039/2885/3845/3265/1839/2069/255324/6464/6654/1956/685/1950 14 Human_herpesvirus_1 R-HSA-190322 FGFR4 ligand binding and activation 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 9965/2264/2253/8823/8074/2249/2247/2246/2251/8822/8817/2254/152831/26281 14 Human_herpesvirus_1 R-HSA-198323 AKT phosphorylates targets in the cytosol 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 84335/7249/2932/10000/2931/23608/572/208/1147/842/207/1027/1026/4193 14 Human_herpesvirus_1 R-HSA-3656237 Defective EXT2 causes exostoses 2 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 6385/221914/6382/375790/2262/9672/2132/2239/2719/2131/2817/3339/6383/10082 14 Human_herpesvirus_1 R-HSA-3656253 Defective EXT1 causes exostoses 1, TRPS2 and CHDS 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 6385/221914/6382/375790/2262/9672/2132/2239/2719/2131/2817/3339/6383/10082 14 Human_herpesvirus_1 R-HSA-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 107/5567/5573/5613/801/805/5568/5566/5577/5575/114/5576/1385/808 14 Human_herpesvirus_1 R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Human_herpesvirus_1 R-HSA-4839744 truncated APC mutants destabilize the destruction complex 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Human_herpesvirus_1 R-HSA-4839748 AMER1 mutants destabilize the destruction complex 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Human_herpesvirus_1 R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 4436/9156/6117/10714/6118/3978/5424/2956/4292/5425/5111/6119/57804/5395 14 Human_herpesvirus_1 R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 4436/9156/6117/10714/4437/6118/3978/5424/4292/5425/5111/6119/57804/5395 14 Human_herpesvirus_1 R-HSA-5467337 APC truncation mutants have impaired AXIN binding 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Human_herpesvirus_1 R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Human_herpesvirus_1 R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Human_herpesvirus_1 R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 79370/7159/23368/332/64065/7157/1121/604/5875/8626/7161/10397/9540/5876 14 Human_herpesvirus_1 R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 9134/57060/1869/8900/144455/898/890/7157/79733/1820/1017/25946/1027/1026 14 Human_herpesvirus_1 R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 7159/51230/23368/5458/10000/7157/5457/54971/8626/208/7161/25946/207/10848 14 Human_herpesvirus_1 R-HSA-69091 Polymerase switching 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 5982/5422/10714/5558/5557/5985/5984/23649/5424/5425/5111/5983/57804/5981 14 Human_herpesvirus_1 R-HSA-69109 Leading Strand Synthesis 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 5982/5422/10714/5558/5557/5985/5984/23649/5424/5425/5111/5983/57804/5981 14 Human_herpesvirus_1 R-HSA-69166 Removal of the Flap Intermediate 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 2237/1763/5422/6117/10714/5558/6118/5557/23649/5424/5425/5111/6119/57804 14 Human_herpesvirus_1 R-HSA-877312 Regulation of IFNG signaling 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 5777/5770/9021/3459/3717/3458/5781/8554/6772/8651/5771/3716/3460/7341 14 Human_herpesvirus_1 R-HSA-8941856 RUNX3 regulates NOTCH signaling 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 182/22938/1387/9794/2648/55534/3280/84441/8850/864/10046/4851/2033/3516 14 Human_herpesvirus_1 R-HSA-8983432 Interleukin-15 signaling 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 6776/2885/9846/3600/3718/6777/6464/6774/6654/3716/6655/3561/3560/3601 14 Human_herpesvirus_1 R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 79718/9612/6907/4204/814/801/805/5566/25942/8841/9611/2874/3065/808 14 Human_herpesvirus_1 R-HSA-9005895 Pervasive developmental disorders 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 79718/9612/6907/4204/814/801/805/5566/25942/8841/9611/2874/3065/808 14 Human_herpesvirus_1 R-HSA-9027284 Erythropoietin activates RAS 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 4893/3717/2885/2056/8660/3845/3265/1399/2057/7409/6464/2889/4067/6654 14 Human_herpesvirus_1 R-HSA-918233 TRAF3-dependent IRF activation pathway 14/6371 14/10654 7.434165159117719e-4 0.0015597386633988439 5.999889297106034e-4 80143/1387/64135/7187/29110/23586/3661/84282/3665/7706/9641/3456/57506/2033 14 Human_herpesvirus_1 R-HSA-110320 Translesion Synthesis by POLH 18/6371 19/10654 7.810508137778441e-4 0.0016290158774805259 6.266379847770623e-4 5982/25898/6117/55666/7314/6118/5985/5984/6233/5111/6119/83932/5429/7311/5983/7316/7415/5981 18 Human_herpesvirus_1 R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 18/6371 19/10654 7.810508137778441e-4 0.0016290158774805259 6.266379847770623e-4 1869/4609/5928/990/7027/7153/5934/993/286826/5111/91750/1874/55957/4149/1875/5933/3065/132660 18 Human_herpesvirus_1 R-HSA-392851 Prostacyclin signalling through prostacyclin receptor 18/6371 19/10654 7.810508137778441e-4 0.0016290158774805259 6.266379847770623e-4 2788/2782/2787/10681/2792/2785/2783/2784/2791/2786/54331/59345/51764/94235/55970/2778/2793/2790 18 Human_herpesvirus_1 R-HSA-6804760 Regulation of TP53 Activity through Methylation 18/6371 19/10654 7.810508137778441e-4 0.0016290158774805259 6.266379847770623e-4 133383/11200/472/79813/4194/56950/7314/7157/6233/10419/26013/7311/7316/2033/91875/133746/10919/4193 18 Human_herpesvirus_1 R-HSA-9012852 Signaling by NOTCH3 40/6371 49/10654 9.317336895573873e-4 0.0019404247340044703 7.46428479757199e-4 4904/182/23385/11060/22938/1387/9794/57534/9787/388585/7314/23286/2648/55534/3280/84441/4854/3714/102/10320/8850/5087/6233/5663/142678/10460/10046/6772/26508/9148/23493/7311/1956/4851/23462/7316/1950/2033/54567/3516 40 Human_herpesvirus_1 R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 27/6371 31/10654 9.462346612908096e-4 0.0019633499629895827 7.552471901764013e-4 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/79023/23636/53371/9688/8480 27 Human_herpesvirus_1 R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 27/6371 31/10654 9.462346612908096e-4 0.0019633499629895827 7.552471901764013e-4 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/79023/23636/53371/9688/8480 27 Human_herpesvirus_1 R-HSA-428930 Thromboxane signalling through TP receptor 21/6371 23/10654 9.469131195438427e-4 0.0019633499629895827 7.552471901764013e-4 2788/2769/2782/2776/2787/10681/2792/2785/2783/2784/2791/2786/54331/59345/51764/94235/55970/2767/2793/9630/2790 21 Human_herpesvirus_1 R-HSA-383280 Nuclear Receptor transcription pathway 42/6371 52/10654 0.001058817978605967 0.002192156870662207 8.432629679899353e-4 7068/5915/6097/7181/5469/2104/9612/8856/2101/7067/5914/9572/8431/7421/10062/7025/2516/5465/2099/7101/5467/2103/5241/7182/3172/10002/2063/9970/2908/9971/29982/367/6095/5468/2100/4306/9611/3164/6256/7376/5916/9975 42 Human_herpesvirus_1 R-HSA-1368082 RORA activates gene expression 17/6371 18/10654 0.0012435928328567195 0.002516943107547164 9.681993763935716e-4 79718/5469/1387/6907/10499/23054/85441/96764/5465/6604/1374/6095/6720/2033/6256/10498/8648 17 Human_herpesvirus_1 R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 17/6371 18/10654 0.0012435928328567195 0.002516943107547164 9.681993763935716e-4 5295/11052/613/6776/11064/2885/9846/7750/8805/26127/5290/399687/6777/1523/9208/6774/6772 17 Human_herpesvirus_1 R-HSA-210993 Tie2 Signaling 17/6371 18/10654 0.0012435928328567195 0.002516943107547164 9.681993763935716e-4 5295/4893/5291/2885/3845/3265/5290/5781/6464/7010/2888/2886/6654/285/5296/284/9046 17 Human_herpesvirus_1 R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 17/6371 18/10654 0.0012435928328567195 0.002516943107547164 9.681993763935716e-4 2810/6790/1647/7027/5934/983/7157/891/5111/1874/25946/5933/2033/995/10498/581/3276 17 Human_herpesvirus_1 R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 13/6371 13/10654 0.0012442112528809636 0.002516943107547164 9.681993763935716e-4 2064/9542/7314/2065/9101/10000/6233/10193/3084/208/7311/207/7316 13 Human_herpesvirus_1 R-HSA-171007 p38MAPK events 13/6371 13/10654 0.0012442112528809636 0.002516943107547164 9.681993763935716e-4 4893/5898/1432/5603/3845/3265/5899/9261/6714/5600/6300/7867/5900 13 Human_herpesvirus_1 R-HSA-179812 GRB2 events in EGFR signaling 13/6371 13/10654 0.0012442112528809636 0.002516943107547164 9.681993763935716e-4 374/4893/7039/2885/3845/3265/1839/2069/255324/6654/1956/685/1950 13 Human_herpesvirus_1 R-HSA-190375 FGFR2c ligand binding and activation 13/6371 13/10654 0.0012442112528809636 0.002516943107547164 9.681993763935716e-4 2250/2253/8823/8074/2249/2247/2246/2251/2263/8822/8817/2254/26281 13 Human_herpesvirus_1 R-HSA-202670 ERKs are inactivated 13/6371 13/10654 0.0012442112528809636 0.002516943107547164 9.681993763935716e-4 1848/5518/51231/5515/1849/5594/5528/5519/5598/1846/5595/5516/1845 13 Human_herpesvirus_1 R-HSA-209543 p75NTR recruits signalling complexes 13/6371 13/10654 0.0012442112528809636 0.002516943107547164 9.681993763935716e-4 8878/3654/3551/7314/8767/6233/7189/7311/4804/5584/4615/7316/4803 13 Human_herpesvirus_1 R-HSA-209560 NF-kB is activated and signals survival 13/6371 13/10654 0.0012442112528809636 0.002516943107547164 9.681993763935716e-4 4790/8878/4792/3654/3551/7314/5970/6233/7189/7311/4804/7316/4803 13 Human_herpesvirus_1 R-HSA-5357786 TNFR1-induced proapoptotic signaling 13/6371 13/10654 0.0012442112528809636 0.002516943107547164 9.681993763935716e-4 7124/7375/1540/8737/841/7128/8772/8717/27005/7186/56957/7132/9099 13 Human_herpesvirus_1 R-HSA-5654227 Phospholipase C-mediated cascade; FGFR3 13/6371 13/10654 0.0012442112528809636 0.002516943107547164 9.681993763935716e-4 2250/5335/2253/8823/8074/2249/2247/2246/8822/8817/2254/26281/2261 13 Human_herpesvirus_1 R-HSA-5658623 FGFRL1 modulation of FGFR1 signaling 13/6371 13/10654 0.0012442112528809636 0.002516943107547164 9.681993763935716e-4 2250/2253/8074/2249/2248/2247/200734/53834/8822/8817/2255/27006/161742 13 Human_herpesvirus_1 R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13/6371 13/10654 0.0012442112528809636 0.002516943107547164 9.681993763935716e-4 7531/10971/7533/2810/11200/7465/7534/983/7532/891/1111/7529/995 13 Human_herpesvirus_1 R-HSA-8847993 ERBB2 Activates PTK6 Signaling 13/6371 13/10654 0.0012442112528809636 0.002516943107547164 9.681993763935716e-4 2064/5753/145957/9542/1839/2065/2069/3084/10718/1956/685/1950/2066 13 Human_herpesvirus_1 R-HSA-9609736 Assembly and cell surface presentation of NMDA receptors 34/6371 41/10654 0.0013307927504699218 0.002688239432995035 0.0010340924015397632 51807/817/347688/10381/7846/81027/1741/1739/1740/8825/818/2902/10376/2906/4747/57576/84617/8573/2904/10382/7277/55327/2905/347733/816/10383/84790/7280/64130/815/112714/2903/1742/88 34 Human_herpesvirus_1 R-HSA-180024 DARPP-32 events 23/6371 26/10654 0.001477841022059867 0.0029810164616407607 0.0011467157404254007 5530/5499/5518/5515/5567/5142/5573/5528/5519/801/805/5568/5566/5577/1020/5516/5533/5575/5532/5576/5534/5144/808 23 Human_herpesvirus_1 R-HSA-202433 Generation of second messenger molecules 28/6371 33/10654 0.0018085202585554488 0.003642839664879164 0.0014013010787816077 5335/3115/3113/3117/3127/5062/916/3702/3932/3120/3937/3123/3122/920/5063/7535/5058/55740/9402/4690/3119/919/27040/915/917/51466/7408/7454 28 Human_herpesvirus_1 R-HSA-8852135 Protein ubiquitination 60/6371 79/10654 0.0018482311550289971 0.0037175247733631676 0.0014300304033512709 11065/7321/56852/65264/8239/55236/56254/3093/7347/7328/10670/5192/7334/7332/80349/7314/90268/79139/10477/92912/7323/29089/7324/6233/23168/7874/5193/6596/123169/9646/79577/7326/5591/7317/51255/8915/5111/92305/9810/8078/118424/5830/7327/7311/5195/9781/3105/997/7319/7320/7336/7316/54926/7415/7322/54623/5828/55284/27338/5194 60 Human_herpesvirus_1 R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 16/6371 17/10654 0.001974715724313052 0.0039662853523898004 0.0015257218143977461 356/929/8737/841/8797/8772/8717/8743/8837/8795/23643/7186/355/7099/353376/148022 16 Human_herpesvirus_1 R-HSA-5205647 Mitophagy 25/6371 29/10654 0.0020381182930423515 0.00407781938869845 0.0015686259166306847 9927/65018/1459/9140/8878/1460/9474/1457/84557/7314/139341/192111/6714/8408/55669/6233/9804/7416/7311/401505/10452/7316/56993/81631/54543 25 Human_herpesvirus_1 R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 25/6371 29/10654 0.0020381182930423515 0.00407781938869845 0.0015686259166306847 2308/84676/4089/4088/3630/56729/2538/847/3484/5443/3066/5105/4303/23410/4287/2908/4852/6648/4087/25942/2309/6720/114907/3065/10891 25 Human_herpesvirus_1 R-HSA-111932 CaMK IV-mediated phosphorylation of CREB 12/6371 12/10654 0.0020822293054189676 0.00407781938869845 0.0015686259166306847 817/814/818/801/805/3838/10645/84254/816/815/1385/808 12 Human_herpesvirus_1 R-HSA-170968 Frs2-mediated activation 12/6371 12/10654 0.0020822293054189676 0.00407781938869845 0.0015686259166306847 5605/1399/5594/4914/673/2889/7529/5595/5604/10818/4803/5906 12 Human_herpesvirus_1 R-HSA-1839130 Signaling by activated point mutants of FGFR3 12/6371 12/10654 0.0020822293054189676 0.00407781938869845 0.0015686259166306847 2250/2253/8823/8074/2249/2247/2246/8822/8817/2254/26281/2261 12 Human_herpesvirus_1 R-HSA-190873 Gap junction degradation 12/6371 12/10654 0.0020822293054189676 0.00407781938869845 0.0015686259166306847 71/1212/1785/2697/1759/4646/1601/1213/1211/1173/8218/60 12 Human_herpesvirus_1 R-HSA-2029481 FCGR activation 12/6371 12/10654 0.0020822293054189676 0.00407781938869845 0.0015686259166306847 2268/2534/6714/7525/2214/2209/6850/4067/919/3055/917/2212 12 Human_herpesvirus_1 R-HSA-2033514 FGFR3 mutant receptor activation 12/6371 12/10654 0.0020822293054189676 0.00407781938869845 0.0015686259166306847 2250/2253/8823/8074/2249/2247/2246/8822/8817/2254/26281/2261 12 Human_herpesvirus_1 R-HSA-210990 PECAM1 interactions 12/6371 12/10654 0.0020822293054189676 0.00407781938869845 0.0015686259166306847 5777/5335/5175/2534/3690/3635/6714/7525/3685/3932/5781/4067 12 Human_herpesvirus_1 R-HSA-2197563 NOTCH2 intracellular domain regulates transcription 12/6371 12/10654 0.0020822293054189676 0.00407781938869845 0.0015686259166306847 4853/9794/388585/55534/3280/84441/3002/10046/2208/2033/1385/3516 12 Human_herpesvirus_1 R-HSA-389359 CD28 dependent Vav1 pathway 12/6371 12/10654 0.0020822293054189676 0.00407781938869845 0.0015686259166306847 941/2534/2885/5062/5879/7409/3932/940/5063/998/5058/942 12 Human_herpesvirus_1 R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 12/6371 12/10654 0.0020822293054189676 0.00407781938869845 0.0015686259166306847 834/55367/472/8738/7157/839/317/843/8626/7161/835/58484 12 Human_herpesvirus_1 R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 12/6371 12/10654 0.0020822293054189676 0.00407781938869845 0.0015686259166306847 7159/23368/8797/7157/8626/7161/8795/8793/3486/355/8794/124446 12 Human_herpesvirus_1 R-HSA-8984722 Interleukin-35 Signalling 12/6371 12/10654 0.0020822293054189676 0.00407781938869845 0.0015686259166306847 3717/3572/10148/3592/7297/6775/3595/821/6774/6772/3716/9466 12 Human_herpesvirus_1 R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 12/6371 12/10654 0.0020822293054189676 0.00407781938869845 0.0015686259166306847 7187/7314/29110/3661/6233/10010/3665/7098/7311/9641/7316/148022 12 Human_herpesvirus_1 R-HSA-9020558 Interleukin-2 signaling 12/6371 12/10654 0.0020822293054189676 0.00407781938869845 0.0015686259166306847 6776/3558/3718/3932/6777/6464/6850/3716/2185/3561/3560/3559 12 Human_herpesvirus_1 R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 12/6371 12/10654 0.0020822293054189676 0.00407781938869845 0.0015686259166306847 5295/5291/3717/2056/8660/5290/5294/2057/4067/5293/2549/23533 12 Human_herpesvirus_1 R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12/6371 12/10654 0.0020822293054189676 0.00407781938869845 0.0015686259166306847 64135/3551/8737/841/8517/23586/84282/8772/7706/843/1147/57506 12 Human_herpesvirus_1 R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 22/6371 25/10654 0.002207035197698154 0.004298391309172128 0.0016534739194370197 51807/10381/10576/7846/81027/10574/10693/10575/10376/84617/10382/7277/347733/10383/84790/22948/7280/10694/112714/7203/908/6950 22 Human_herpesvirus_1 R-HSA-429947 Deadenylation of mRNA 22/6371 25/10654 0.002207035197698154 0.004298391309172128 0.0016534739194370197 26986/25904/1973/55571/57472/85456/29883/1981/1977/9924/5073/4850/255967/246175/4848/23019/1975/1974/4849/10605/9337/9775 22 Human_herpesvirus_1 R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 22/6371 25/10654 0.002207035197698154 0.004298391309172128 0.0016534739194370197 22938/1387/9794/9787/388585/23286/2648/55534/3280/84441/4854/10320/8850/5087/10046/6772/26508/23493/4851/23462/2033/3516 22 Human_herpesvirus_1 R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 22/6371 25/10654 0.002207035197698154 0.004298391309172128 0.0016534739194370197 3107/10484/811/567/3106/3309/9632/3133/6892/22872/10134/6396/3135/10802/6890/821/2923/9871/3105/6891/3134/10427 22 Human_herpesvirus_1 R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 19/6371 21/10654 0.002232053377734537 0.004323263881153863 0.0016630417196029474 4790/4792/1660/3551/11035/8737/29110/8517/5970/3661/4791/23220/7098/81030/1147/147945/4615/4793/148022 19 Human_herpesvirus_1 R-HSA-500657 Presynaptic function of Kainate receptors 19/6371 21/10654 0.002232053377734537 0.004323263881153863 0.0016630417196029474 2788/5331/2782/2787/10681/2792/2785/2783/2784/2791/23236/2786/54331/59345/51764/94235/55970/2793/2790 19 Human_herpesvirus_1 R-HSA-5218921 VEGFR2 mediated cell proliferation 19/6371 21/10654 0.002232053377734537 0.004323263881153863 0.0016630417196029474 4893/5335/5579/5578/3845/3265/8877/5921/6714/5580/3791/801/805/5170/5590/7422/3708/10768/808 19 Human_herpesvirus_1 R-HSA-5621575 CD209 (DC-SIGN) signaling 19/6371 21/10654 0.002232053377734537 0.004323263881153863 0.0016630417196029474 9252/4893/4790/1387/2534/5894/3845/3265/5062/5567/5970/5568/5566/4067/5063/30835/5971/5058/2033 19 Human_herpesvirus_2 R-HSA-5683057 MAPK family signaling cascades 281/4920 294/10654 4.294152690979103e-78 6.011813767370744e-75 2.305281970946676e-75 2308/5689/374/2118/3725/2674/4893/6711/2250/1437/71/5682/1844/1850/1848/5526/817/84292/7039/27327/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/22866/5605/4609/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/192669/4296/5894/1847/3563/1741/9542/1739/2885/6709/8660/8997/8826/5518/2252/1740/4140/4343/2253/3845/5623/3265/4763/3569/5062/5696/5691/2323/7314/3572/5879/5515/5923/5718/818/10156/1839/3667/8823/8831/2065/5700/3815/122706/5707/5567/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/3337/4902/2260/5528/2902/10125/983/3718/2249/25780/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/1445/5710/8555/896/5719/2906/6233/51332/2266/2246/7514/2251/5154/115727/2243/1843/3570/255324/26523/369/801/200734/7297/5781/4747/1846/11221/28956/805/22821/9462/3562/6464/6712/2904/5747/283455/3674/7010/5568/2322/2675/3315/409/5706/1438/673/2676/8315/221002/2263/4233/5597/84078/5714/64926/5566/6710/5688/5159/5687/5708/3084/5063/5529/816/998/9693/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/5058/5924/7529/5595/25759/5516/8822/5786/27161/815/5684/685/5720/2309/5604/3561/5525/153090/10642/10048/5690/57690/5717/9491/3568/8817/10817/10197/192670/8550/54518/2254/7316/10213/152831/1950/3560/57731/26281/10818/5715/8437/10256/2261/5701/27040/5922/5685/2255/8649/53358/5686/2066/6708/27006/8556/5979/23112/1742/5527/5716/88/5906/5155/9048/4254/399473/808/3559/8202/5693/5721/5245/5156/161742/284 281 Human_herpesvirus_2 R-HSA-9607240 FLT3 Signaling 259/4920 267/10654 1.4712154876857392e-76 1.0298508413800175e-73 3.949052098524879e-74 5295/5689/374/2674/4893/6711/2250/1437/71/5682/1844/5291/1850/1848/5526/817/84292/7039/5908/3082/143471/2064/5705/8452/6776/4684/5709/9978/5695/1852/2668/22866/5605/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/1847/3563/1741/9542/1739/2885/6709/8660/8826/9846/5518/2252/1740/4140/2253/3845/5623/3265/4763/5696/5691/2323/7314/5515/54106/5923/5718/818/10156/1839/5290/3667/8823/8831/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/57761/5921/4902/2260/5528/2902/10125/3718/2249/25780/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/1445/5710/5719/2906/6233/51332/2266/2246/2251/5154/115727/2243/1843/6777/255324/369/801/200734/5781/30849/4747/1846/11221/28956/805/22821/5170/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/409/5706/1438/673/2676/8315/221002/2263/4233/84078/5714/64926/6710/5688/5159/5687/5708/3084/5529/816/9693/208/6654/5704/10718/3716/7311/7450/1956/60/5536/2549/5694/5924/7529/5595/25759/5516/8822/5786/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10817/10197/54518/2254/7316/10213/152831/1950/3560/5289/3055/57731/26281/10818/5715/8437/10256/2261/5701/27040/5922/5685/2255/8649/53358/5686/2066/6708/27006/5979/1742/5527/5716/88/5906/5155/9048/4254/5296/399473/808/3559/5693/5721/5245/5156/161742/284 259 Human_herpesvirus_2 R-HSA-5684996 MAPK1/MAPK3 signaling 249/4920 255/10654 9.039296160611016e-76 4.218338208285141e-73 1.617558260319866e-73 5689/374/2674/4893/6711/2250/1437/71/5682/1844/1850/1848/5526/817/84292/7039/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/22866/5605/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/1847/3563/1741/9542/1739/2885/6709/8660/8826/5518/2252/1740/4140/2253/3845/5623/3265/4763/3569/5696/5691/2323/7314/3572/5515/5923/5718/818/10156/1839/3667/8823/8831/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/4902/2260/5528/2902/10125/983/3718/2249/25780/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/1445/5710/5719/2906/6233/51332/2266/2246/2251/5154/115727/2243/1843/3570/255324/369/801/200734/7297/5781/4747/1846/11221/28956/805/22821/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/409/5706/1438/673/2676/8315/221002/2263/4233/84078/5714/64926/6710/5688/5159/5687/5708/3084/5529/816/9693/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/5924/7529/5595/25759/5516/8822/5786/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10817/10197/54518/2254/7316/10213/152831/1950/3560/57731/26281/10818/5715/8437/10256/2261/5701/27040/5922/5685/2255/8649/53358/5686/2066/6708/27006/5979/1742/5527/5716/88/5906/5155/9048/4254/399473/808/3559/5693/5721/5245/5156/161742/284 249 Human_herpesvirus_2 R-HSA-5673001 RAF/MAP kinase cascade 243/4920 249/10654 9.508312767938325e-74 3.327909468778414e-71 1.2761156609601435e-71 5689/374/2674/4893/6711/2250/1437/71/5682/1844/1850/1848/5526/817/84292/7039/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/22866/5605/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/1847/3563/1741/9542/1739/2885/6709/8660/8826/5518/2252/1740/4140/2253/3845/5623/3265/4763/5696/5691/2323/7314/5515/5923/5718/818/10156/1839/3667/8823/8831/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/4902/2260/5528/2902/10125/3718/2249/25780/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/1445/5710/5719/2906/6233/51332/2266/2246/2251/5154/115727/2243/1843/255324/369/801/200734/4747/1846/11221/28956/805/22821/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/409/5706/1438/673/2676/8315/221002/2263/4233/84078/5714/64926/6710/5688/5159/5687/5708/3084/5529/816/9693/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/5924/7529/5595/25759/5516/8822/5786/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10817/10197/54518/2254/7316/10213/152831/1950/3560/57731/26281/10818/5715/8437/10256/2261/5701/27040/5922/5685/2255/8649/53358/5686/2066/6708/27006/5979/1742/5527/5716/88/5906/5155/9048/4254/399473/808/3559/5693/5721/5245/5156/161742/284 243 Human_herpesvirus_2 R-HSA-3700989 Transcriptional Regulation by TP53 328/4920 365/10654 5.231547381010409e-72 1.4648332666829148e-69 5.617029819611175e-70 6884/6875/834/5563/3725/9134/4436/83990/64769/9156/57060/1763/7531/1459/79370/7486/6874/10971/9997/133383/9212/5982/27327/7295/7533/2810/55367/1460/11200/472/53632/79813/5431/7001/639/5435/5433/1869/28996/84289/1457/6790/25904/29117/4194/1647/5928/1432/1387/4683/10325/56950/51499/2965/84126/5439/192669/1107/8900/6873/5371/2475/672/55571/6881/2967/51616/5518/1386/55835/10670/4513/4343/6117/11198/7159/57472/904/144455/85456/29883/51497/51230/637/64121/83695/7296/7314/5515/1263/27166/23368/23774/6118/2176/3622/7027/7832/51422/7249/404672/898/117584/27244/7534/332/5438/5934/64065/1351/116028/890/10769/983/1643/8797/9656/5519/27154/5458/83860/57459/2821/2177/10000/5985/2877/900/7994/2068/54541/3066/7157/5984/6233/1025/2353/604/63970/839/10419/5325/50484/5600/6883/7936/6829/79733/26523/7874/317/2744/5608/5884/5810/57521/26155/26013/5875/253260/28956/25920/5170/80010/2963/5434/83667/1820/7862/1029/389541/5457/9219/8445/7532/5436/1345/55240/204851/6878/4869/5931/58528/4850/4292/580/11073/891/80196/54971/4331/5366/641/5111/1108/8148/2966/246175/64223/2962/84883/6119/147923/3364/5571/10524/54457/4848/8812/144715/23019/1616/843/6794/54815/94241/1874/10128/25824/6009/905/1111/2071/55215/8626/208/79109/55004/7311/7161/5562/6880/6908/5983/1340/4697/5564/6882/5565/1020/53615/10397/8795/5432/665/7248/6877/7529/5516/1017/27161/27113/9891/6917/5440/27165/5305/8621/902/5883/25946/9540/5430/10111/8793/207/22974/57690/835/4849/1027/58484/3486/355/6749/545/5441/8794/192670/153129/8550/7469/9337/7316/6872/2539/1026/54205/5933/124446/5395/9150/6879/112858/5876/143686/10848/5437/9099/8649/28984/51755/2033/995/5728/3065/91875/6827/23112/10498/10542/5527/1349/2968/5932/8851/5300/7156/581/1327/3276/5052/138474/133746/1022/8178/10919/4193 328 Human_herpesvirus_2 R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 235/4920 244/10654 2.2335016181661762e-67 5.211503775721078e-65 1.998396184675e-65 8449/23165/6633/8683/6431/84271/55696/4904/51639/51585/9128/199746/23450/348995/57122/5431/9092/23511/81608/5435/6625/5433/51645/3190/1477/9416/65109/56339/22826/23279/8233/22938/988/23020/23225/6631/3181/5439/1660/9410/6638/57721/9877/9972/8021/3312/10907/10291/55746/26121/10262/53981/7919/6432/10084/8563/6430/51340/56001/6627/6936/83443/11051/80145/9129/9879/10081/8106/51690/27238/55749/5438/85313/10762/54883/22794/9785/11338/1655/9343/29107/3185/4116/6626/11157/285755/1478/24144/79902/9883/51213/10236/10250/4670/26097/51362/10465/55660/25949/23283/2521/1977/3191/10285/6636/23524/10914/57187/6396/129401/79228/8175/2733/84950/3188/84324/56259/5725/1994/10450/7536/4928/2963/6635/5434/5903/220988/6632/10283/55706/7175/24148/154007/7884/23350/5436/10523/6428/27258/10212/6637/55110/5093/55954/84321/6429/57819/4927/10181/2962/10898/10569/23658/6434/9295/84844/10482/51692/10421/11193/8086/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/81929/5440/55599/51691/10946/9631/27339/5430/79869/85437/11325/57703/3184/25804/29894/11017/51503/3178/79023/5441/23636/3183/79622/10594/4686/8189/23398/10713/53371/10978/5546/7307/10772/9688/9984/5437/6629/10189/10949/51729/11066/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/84248/6427/5356/57461/84991/8480/10992/55339/6628 235 Human_herpesvirus_2 R-HSA-5663205 Infectious disease 331/4920 383/10654 6.762425275200716e-63 1.3524850550401432e-60 5.1862208877479175e-61 6158/6884/23165/6875/5689/6138/2237/6227/7852/6206/6234/6191/162/6128/5682/6132/6129/27243/6874/6176/1174/811/6224/6146/348995/6154/143471/6202/57122/5705/6169/5431/23511/5435/5709/6175/9978/5433/6218/5695/2960/292/567/6173/23279/5605/6167/5711/23327/116832/29082/23225/5683/2965/2534/6156/27183/5699/6143/5439/5702/6456/6873/3836/6139/30011/2885/163/9972/6881/2967/51616/3921/8021/7040/11198/904/55690/51497/5062/55746/6208/5696/6170/5691/7296/7314/5879/5718/3303/8945/6203/51606/1839/161/402569/5606/6147/5700/122706/5707/2959/8027/10053/6222/2060/8106/23198/404672/84168/9636/10015/91782/5438/6134/3978/10762/6155/1500/4836/926/9397/6714/6231/9861/79902/6142/9883/23521/89853/83860/999/5698/9146/6455/5692/5713/5710/2068/5902/6207/5478/5719/6233/6844/7514/1025/3932/1213/5610/1211/6188/6396/129401/6883/7936/1175/6829/801/5608/8907/200916/6122/2957/805/25920/6230/1173/4928/2963/3838/5434/5903/6857/6194/55706/7175/79643/6166/1938/5436/6136/6878/6125/4869/821/5706/6232/160/6160/5611/920/4233/4331/5714/6193/6210/4927/6229/8148/6205/2966/2962/10898/3840/5688/54457/8812/5687/5708/128866/140801/6235/905/6181/2071/5901/8086/5704/3326/7311/6223/25873/93343/6880/6908/7251/8905/5694/3304/1104/2547/9045/6882/2961/6187/6416/5432/6168/22916/1234/6157/6137/6877/5905/6144/3837/6917/81929/5440/164/5684/9349/8065/4736/5720/902/51121/9631/5604/1499/3159/6159/6217/3843/5430/6152/5690/7520/5717/9491/6500/127833/6749/51065/6141/79023/6123/5441/23636/10197/7469/919/130340/6164/4686/7316/10213/6872/53371/3055/6209/9688/11224/6165/8731/6130/9150/6879/5715/9525/6204/5701/2958/867/6228/5437/5685/3320/8815/5686/6124/6827/5609/2968/5716/6189/808/6135/6201/375/6161/138474/1022/5693/10254/5721/6457/8178/8480/6133 331 Human_herpesvirus_2 R-HSA-449147 Signaling by Interleukins 380/4920 461/10654 1.385196119949295e-60 2.4240932099112665e-58 9.295395015449218e-59 5295/729230/8454/3605/7124/2308/834/1052/5689/3725/7291/5777/9252/1437/4790/5682/5291/1511/26469/5657/5783/27178/1848/356/3593/5803/9021/8878/6624/5908/3082/5743/3091/941/143471/10538/3383/5705/11009/6097/6349/6657/3576/3313/3662/6776/3688/4985/5709/6175/9978/2920/5695/1435/4792/3936/59307/7133/3606/177/4609/3603/5898/5711/4988/1432/3558/3717/4088/836/5683/2534/5699/3181/5702/4001/3654/3563/2885/85480/8660/282618/6196/3594/1154/50604/9846/6347/5518/1386/6382/7040/3588/6197/4282/7334/3600/3312/1399/3551/55801/3569/5062/5696/5691/51231/4692/7314/3572/3596/5515/257397/3598/5718/54014/10148/8945/5601/1072/3592/5290/3667/6627/5606/90865/64109/9049/3587/7412/5700/122706/5707/27250/1849/29110/1439/5594/4582/23198/23118/6367/4312/9987/8517/6778/7534/6810/332/5528/4313/3565/3934/3976/50615/3185/5970/5443/9261/3718/3627/8809/9861/149233/5519/5598/4208/3567/598/2247/5698/5692/5713/2335/595/6195/5710/3458/10454/7157/5478/5719/6233/7525/6844/7409/2353/604/6809/3932/7076/302/552900/51561/3570/8835/5600/6777/6773/7850/7297/5781/5608/4791/1846/59067/3557/9655/3562/351/6464/3566/6597/5782/6351/7184/9180/3589/6775/50616/3684/3595/54472/821/4318/5706/3726/58480/301/4478/1438/53833/3581/79155/6774/920/6850/5780/1440/5714/6772/8651/7867/5566/8503/1901/3552/2889/5688/79923/5687/4067/3636/5708/5602/29949/57162/5771/998/6648/7189/163702/112744/6654/5704/3716/7311/2939/1270/6888/5293/2185/6655/6356/5008/5694/246778/6416/1234/3586/3554/829/5595/3556/5516/6095/1147/5778/1845/596/5684/2208/5720/6885/2309/5604/4215/3561/3578/207/5292/5451/7422/5690/3553/2625/1230/5717/2919/9491/6500/3568/25930/246330/10197/4615/3597/2357/7316/10213/3560/6352/4314/1441/4205/3055/1026/6348/4793/3146/6647/6364/5715/7132/5701/867/466/6950/23291/5685/3320/5686/4843/9466/6288/2002/942/6285/5609/1398/58985/948/5716/1385/53832/6363/3575/4507/6845/5296/6935/3687/5599/5784/7431/375/3977/3559/3574/3929/3162/1489/57161/1278/4170/5693/3689/5721/3601/5724/5034 380 Human_herpesvirus_2 R-HSA-9006925 Intracellular signaling by second messengers 274/4920 305/10654 4.811102331420836e-60 7.483936959987966e-58 2.8697803380404985e-58 5295/1912/2308/5689/374/3725/6591/3643/2250/5335/5682/5291/1822/1459/5526/9112/817/6045/5578/7039/27327/80012/3082/1460/941/143471/2064/5705/5709/5695/107/1457/1911/4734/11060/5711/5928/10325/5683/145957/2534/23512/9965/57332/5699/2444/2264/3630/5702/192669/1107/8975/3654/5371/9542/2885/2475/8660/5518/1386/10670/2252/4343/2253/64121/5696/814/5691/7314/5879/5515/5718/818/1839/5290/3667/8823/90865/2065/23186/5700/3815/122706/5707/5567/2146/51564/5594/2069/84335/84232/8074/7249/23198/112/57761/2260/5573/5528/111/2249/6714/2099/9861/7101/81847/2248/5519/2932/84733/57459/2247/5698/10000/5692/5713/5710/3066/7157/5719/6233/5580/7409/2246/2251/5154/3932/2931/331/8726/5153/196883/8394/115/255324/26523/7874/801/5781/57521/23608/6015/253260/28956/805/5170/3838/572/23239/389541/9219/8535/4303/5568/930/5931/58528/5706/6199/113/2263/4233/5714/10645/1108/2122/64223/5566/84254/10014/8503/5688/5159/5687/5708/3084/54815/6009/5529/816/7189/208/5577/5704/10718/79109/55004/57504/7311/5293/1956/648/2549/5694/23466/53615/109/5595/3556/5516/1147/8822/27161/815/5684/8841/685/5305/5720/2309/5468/5525/5575/842/5978/10273/207/5690/57690/5717/1027/9491/8817/114/3708/10197/108/192670/4615/153129/2100/2254/7316/10213/152831/1950/1026/10768/26281/57167/10818/5715/1958/2261/5701/5576/5685/2255/8649/3164/5686/5728/6615/3065/2066/27006/23028/942/5987/23112/10542/5527/5716/1385/5155/4254/5296/5581/808/5693/5721/5137/5156/4193 274 Human_herpesvirus_2 R-HSA-5663202 Diseases of signal transduction 320/4920 377/10654 7.209722247671983e-57 1.0093611146740775e-54 3.870482469802854e-55 5295/8454/2308/27123/5689/374/4893/11052/2250/5335/71/79718/5682/5291/892/5526/817/1452/7039/9530/613/182/5908/3082/941/55109/143471/2064/5705/54845/5431/6776/5435/5709/9978/5433/5695/8546/9759/9612/22866/5605/4609/4089/22938/5037/5711/1387/3717/10827/4088/2244/5683/145957/324/2534/3690/408/9965/5699/6400/8312/11064/5439/2264/5702/4296/5894/6868/9794/9542/2885/2475/8660/79412/8826/9846/5518/2252/6469/1185/4140/7040/2253/3845/388585/3265/4763/5696/7750/5691/7314/5879/5515/5718/818/8805/1839/26127/5290/3667/8823/79885/2065/2648/9734/55750/5700/3815/122706/5707/10956/8844/51564/7094/8322/55534/5594/3280/2069/84335/8074/7249/23198/84441/7414/10533/10013/23164/2260/5438/5528/3714/102/57085/2249/6714/2099/9861/2248/5519/9061/8850/399687/2932/2247/5698/10000/5692/5713/2335/1445/5710/3066/5719/6233/2266/7409/2246/4040/2251/5154/3932/2931/2243/7855/6777/255324/369/801/5781/5663/1523/57670/253260/805/5170/2963/5434/7276/6464/572/283455/3674/5436/4303/409/930/5706/6199/10046/9208/84447/673/8315/6774/2263/4233/1024/5714/6772/6934/64223/10014/2962/8503/5688/5159/5687/5708/3084/26508/5529/816/4087/208/6654/5704/10718/79109/56829/7048/23493/7311/5293/7450/1956/11160/60/9444/2549/5694/4851/5432/22916/11140/7529/5595/5516/4000/1147/8822/27044/815/5440/5684/22906/8841/685/5720/8087/1487/2309/5604/1499/10018/5525/10142/842/5430/23462/207/5690/5717/1027/9491/6500/8817/5441/10197/54518/2100/2254/4686/7316/10213/152831/1950/9611/1026/26281/10818/7415/5715/80853/10256/2261/5701/867/5437/5685/2255/3164/3320/5686/2033/54894/55294/5728/3065/2066/27006/942/5527/1488/5716/1385/5906/5155/54567/4254/5296/808/3516/9715/5693/5721/5245/5156/4193 320 Human_herpesvirus_2 R-HSA-72172 mRNA Splicing 186/4920 191/10654 5.764741352769888e-56 7.336943539888948e-54 2.813414440107792e-54 8449/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/5431/9092/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/8233/22938/988/23020/6631/3181/5439/1660/9410/6638/3312/10907/10291/26121/10262/53981/6432/10084/6430/51340/6627/6936/83443/11051/9129/9879/10081/8106/51690/27238/55749/5438/85313/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/10236/10250/4670/51362/10465/55660/25949/23283/2521/3191/10285/6636/23524/10914/8175/84950/3188/56259/5725/1994/10450/7536/2963/6635/5434/220988/6632/10283/24148/154007/23350/5436/10523/6428/27258/6637/55110/5093/55954/6429/57819/10181/2962/10898/10569/23658/6434/9295/84844/51692/10421/11193/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/55599/51691/10946/27339/5430/79869/85437/11325/57703/3184/25804/29894/11017/51503/3178/5441/3183/79622/10594/4686/8189/23398/10713/10978/5546/7307/10772/5437/6629/10189/10949/51729/11066/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/57461/84991/10992/55339/6628 186 Human_herpesvirus_2 R-HSA-1257604 PIP3 activates AKT signaling 239/4920 264/10654 6.432410722324293e-54 7.50447917604501e-52 2.8776574284082366e-52 5295/1912/2308/5689/374/3725/6591/3643/2250/5682/5291/1822/1459/5526/9112/6045/7039/27327/80012/3082/1460/941/143471/2064/5705/5709/5695/1457/1911/4734/11060/5711/5928/10325/5683/145957/2534/23512/9965/57332/5699/2444/2264/3630/5702/192669/1107/8975/3654/5371/9542/2885/2475/8660/5518/1386/10670/2252/4343/2253/64121/5696/5691/7314/5879/5515/5718/1839/5290/3667/8823/90865/2065/23186/5700/3815/122706/5707/2146/51564/5594/2069/84335/84232/8074/7249/23198/57761/2260/5528/2249/6714/2099/9861/7101/81847/2248/5519/2932/84733/57459/2247/5698/10000/5692/5713/5710/3066/7157/5719/6233/7409/2246/2251/5154/3932/2931/331/8726/8394/255324/26523/7874/5781/57521/23608/6015/253260/28956/5170/572/23239/389541/9219/8535/4303/930/5931/58528/5706/6199/2263/4233/5714/1108/2122/64223/10014/8503/5688/5159/5687/5708/3084/54815/6009/5529/7189/208/5704/10718/79109/55004/57504/7311/5293/1956/648/2549/5694/23466/53615/5595/3556/5516/1147/8822/27161/5684/8841/685/5305/5720/2309/5468/5525/842/5978/10273/207/5690/57690/5717/1027/9491/8817/10197/192670/4615/153129/2100/2254/7316/10213/152831/1950/1026/26281/57167/10818/5715/1958/2261/5701/5685/2255/8649/3164/5686/5728/6615/3065/2066/27006/23028/942/5987/23112/10542/5527/5716/1385/5155/4254/5296/5693/5721/5156/4193 239 Human_herpesvirus_2 R-HSA-72163 mRNA Splicing - Major Pathway 178/4920 183/10654 2.6358871103394385e-53 2.838647657288626e-51 1.0885039888851123e-51 8449/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/5431/9092/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/22938/988/23020/6631/3181/5439/1660/9410/6638/3312/10907/10291/26121/10262/53981/6432/10084/6430/51340/6627/6936/83443/11051/9129/9879/8106/51690/27238/55749/5438/85313/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/10236/10250/4670/51362/10465/55660/25949/23283/2521/3191/10285/6636/23524/10914/8175/84950/3188/56259/5725/1994/10450/7536/2963/6635/5434/220988/6632/10283/24148/23350/5436/10523/6428/27258/6637/55110/5093/6429/57819/10181/2962/10898/10569/23658/6434/9295/84844/51692/10421/11193/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/51691/10946/27339/5430/79869/11325/57703/3184/25804/29894/11017/51503/3178/5441/3183/10594/4686/8189/23398/10713/10978/5546/7307/10772/5437/6629/10189/10949/51729/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/57461/84991/10992/55339/6628 178 Human_herpesvirus_2 R-HSA-453274 Mitotic G2-G2/M phases 185/4920 198/10654 4.090965287915776e-47 4.0909652879157765e-45 1.568716012659433e-45 114791/10844/8454/5689/440145/5682/7531/11190/203068/54801/51807/63943/347688/79441/143471/10381/5705/5116/5048/5709/9978/1869/5695/8655/6790/9702/5711/5928/7846/7840/5683/5699/11064/5702/5520/8900/28227/5518/55835/29922/23332/7465/93323/5696/5691/7314/5515/5718/8945/4659/5700/122706/5707/1454/23198/993/890/983/9861/79959/5519/5698/5692/5713/80097/10376/5710/10540/7157/85378/5719/6233/7514/54930/54820/1453/27229/9793/4218/5500/84617/2305/11258/22981/8636/51512/7532/84962/55125/10382/121441/7277/5706/9133/286826/9814/653784/23354/728642/891/9738/4331/1639/5714/55722/4957/5566/5688/5687/91750/7283/5708/22919/984/10426/22994/79866/1069/5577/5704/3326/55957/7311/10133/10383/5347/84790/80184/5694/22897/5108/7280/10806/1778/5516/115106/1017/22822/22995/55559/5684/994/5720/4605/902/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/1781/7316/10213/80321/1026/10121/1871/5715/84131/9088/5701/23291/5685/3320/5686/2033/995/10733/4751/27175/80254/5716/9662/55142/1022/8481/5693/5721/132660/55755 185 Human_herpesvirus_2 R-HSA-69275 G2/M Transition 183/4920 196/10654 1.741496431651298e-46 1.6253966695412113e-44 6.232724071173067e-45 114791/10844/8454/5689/440145/5682/7531/11190/203068/54801/51807/63943/347688/79441/143471/10381/5705/5116/5048/5709/9978/5695/8655/6790/9702/5711/5928/7846/7840/5683/5699/11064/5702/5520/8900/28227/5518/55835/29922/23332/7465/93323/5696/5691/7314/5515/5718/8945/4659/5700/122706/5707/1454/23198/993/890/983/9861/79959/5519/5698/5692/5713/80097/10376/5710/10540/7157/85378/5719/6233/7514/54930/54820/1453/27229/9793/4218/5500/84617/2305/11258/22981/8636/51512/7532/84962/55125/10382/121441/7277/5706/9133/286826/9814/653784/23354/728642/891/9738/4331/1639/5714/55722/4957/5566/5688/5687/91750/7283/5708/22919/984/10426/22994/79866/1069/5577/5704/3326/55957/7311/10133/10383/5347/84790/80184/5694/22897/5108/7280/10806/1778/5516/115106/1017/22822/22995/55559/5684/994/5720/4605/902/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/1781/7316/10213/80321/1026/10121/5715/84131/9088/5701/23291/5685/3320/5686/2033/995/10733/4751/27175/80254/5716/9662/55142/1022/8481/5693/5721/132660/55755 183 Human_herpesvirus_2 R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 366/4920 473/10654 1.3457299439986782e-45 1.1775137009988435e-43 4.515278101574513e-44 5295/3675/374/5777/627/3643/9252/4893/857/2250/2670/5335/71/5579/5770/5291/26469/1848/5578/7039/3249/1785/5908/3082/51741/2064/535/54845/8828/5431/50617/6696/6776/5435/3688/10312/5433/5753/7423/4734/10413/5605/3910/8569/5898/1432/3717/55824/145957/2534/9475/3690/9965/5439/2264/5603/3630/6456/83737/6868/4145/9542/30011/2885/2475/8660/6093/163/6196/9846/1759/5518/8440/2252/8874/9564/2253/6197/3845/3265/1399/8877/5062/10252/51231/56034/2323/5829/7314/5879/5515/6387/5607/54106/51606/1839/3918/161/5290/3667/5899/8823/23768/2065/5340/3815/5567/8027/10006/9550/1849/2060/9114/5594/2069/8074/284217/9101/23118/57761/5921/6778/2260/5438/348/5528/9306/1500/3185/11059/102/9261/2249/6714/2099/2248/1447/5519/5598/4208/4670/2567/4909/2247/4914/10810/10000/9146/6455/2335/64759/6195/3728/8471/1445/84951/3925/6233/7525/7410/5580/2324/7409/2246/23191/3685/2251/5154/57610/3932/1213/3791/1729/1211/29924/5600/6777/255324/1175/6300/528/801/200734/5781/30849/5663/5725/1846/253260/805/25920/5170/4908/1173/2963/5434/5590/6464/80310/85440/653361/5241/2904/6461/5747/5782/7424/5436/10019/10193/5568/2322/7074/3315/2241/10451/4318/382/1277/160/3912/673/527/6774/2263/4233/6772/8651/26052/7867/64223/5566/2962/1003/8503/5795/2889/10163/5159/4067/3084/23767/55845/5063/5771/1111/5796/998/3481/2886/3913/80004/208/6654/5867/10718/79109/5900/7311/2185/387/53834/1956/60/2549/5058/1020/5432/3480/22916/11140/4916/7529/63916/5595/25759/5516/8822/1845/10253/9402/5440/8065/685/26018/558/4915/1495/5604/1499/4690/1299/5430/10048/10273/207/7422/10458/3178/8817/10817/3708/5441/58513/2254/4686/7316/152831/1950/9611/51072/9047/4205/5289/57498/3915/10768/26281/10818/1281/3673/23545/2261/867/5437/466/245972/2255/53358/3320/4846/4803/2002/2066/3914/27006/6285/1742/200958/1398/3187/5774/1385/5228/5906/3479/5155/23163/4254/8851/5296/5581/581/808/10076/7059/7057/1278/11033/10254/6457/51382/5156/161742/2887/2242 366 Human_herpesvirus_2 R-HSA-69242 S Phase 154/4920 161/10654 4.1873323276294954e-43 3.35927254462483e-41 1.2881421035779422e-41 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/10274/5925/143471/5705/5709/5422/9978/1869/4174/5753/5695/84515/4609/4998/5711/5928/5683/990/5699/5702/8900/51529/29945/51434/157570/6117/29882/5001/10714/7465/5558/5696/5691/7314/996/5718/6118/23594/7027/5700/122706/5707/23198/898/3978/91768/5934/5557/993/890/51433/9861/2932/6502/5698/10000/5692/5985/5713/119504/595/4175/5710/5984/7324/5719/64682/6233/113130/23649/1163/5424/4999/4172/1019/5000/8318/246184/4173/5706/286826/23047/8881/5885/4331/5425/5714/5111/6119/5688/5687/91750/5427/5708/1874/8243/81620/10393/208/5704/55957/51343/23595/7311/25906/51659/5983/5694/4176/1017/5684/994/5720/902/57804/207/9837/5690/5717/1027/9491/6500/23244/10735/10197/4149/7316/10213/1875/1026/5426/4171/5715/5701/5685/5686/9126/5716/114799/5981/1022/5693/5721/132660 154 Human_herpesvirus_2 R-HSA-68877 Mitotic Prometaphase 183/4920 200/10654 4.319064700231924e-43 3.35927254462483e-41 1.2881421035779422e-41 114791/10844/55839/11130/440145/6249/9735/7531/1459/11190/203068/5526/54801/51807/9212/347688/10274/1460/147841/348995/79441/10381/57122/5116/1780/23122/5048/57405/8655/1457/23279/9702/2491/7846/7840/1060/11064/11004/9184/5518/55835/29922/23332/25909/10726/81930/55746/93323/5515/79682/10403/64151/25936/1454/3619/64105/332/10051/5528/983/79902/3796/79959/5519/81565/80097/91687/10376/23397/10540/85378/83540/7514/54930/54820/113130/6396/1453/27229/64946/9793/140735/220134/84617/4928/5903/11258/22981/55055/8636/80776/1783/401541/7532/55125/10382/79172/121441/7277/9133/79980/6232/23047/9814/653784/5885/23354/891/5501/9738/1639/55722/4957/5566/54821/9183/1062/699/7283/22919/8243/10426/5529/22994/51143/1069/5577/10383/5347/84790/84643/80184/22897/5108/10592/7280/10806/1778/5516/115106/4926/5905/22995/55559/81929/54908/55143/5525/10142/1058/991/79019/348235/80152/1063/8379/95681/23244/23421/55920/79023/10735/1781/80321/4085/55166/10121/84131/3320/79003/9126/9918/10733/4751/5527/27175/80254/701/57551/9662/55142/8481/55755 183 Human_herpesvirus_2 R-HSA-5633007 Regulation of TP53 Activity 153/4920 160/10654 8.819429884335568e-43 6.49852728319463e-41 2.491916477014482e-41 6884/6875/5563/83990/64769/9156/1763/1459/7486/6874/133383/9212/5982/1460/11200/472/53632/79813/639/28996/84289/1457/6790/29117/4194/5928/1432/4683/56950/84126/1107/8900/6873/5371/2475/672/6881/51616/5518/6117/11198/7159/51230/83695/7314/5515/1263/23368/23774/6118/3622/51422/117584/116028/890/983/5519/27154/5458/83860/57459/10000/5985/900/7994/3066/7157/5984/6233/10419/5600/6883/7874/5608/5884/5810/26155/26013/253260/5170/80010/7862/1029/5457/9219/8445/204851/6878/5931/580/11073/80196/54971/641/1108/8148/64223/6119/3364/5571/10524/54457/144715/1616/6794/54815/94241/1111/8626/208/79109/7311/7161/5562/6880/6908/5983/5564/6882/5565/1020/53615/6877/5516/1017/9891/5305/5883/25946/10111/207/22974/6749/545/8550/7316/6872/6879/112858/10848/9099/2033/3065/91875/5527/5932/8851/5300/7156/138474/133746/10919/4193 153 Human_herpesvirus_2 R-HSA-2555396 Mitotic Metaphase and Anaphase 184/4920 202/10654 1.3179457188591145e-42 9.2256200320138e-41 3.537643771674465e-41 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/5520/51529/4001/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/25936/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/7444/5698/5692/5713/91687/119504/10376/5710/7324/2010/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/26271/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/7443/1781/7316/10213/4085/55166/5715/5701/5685/8815/5686/79003/9126/9232/23592/5527/9700/5716/701/57551/5693/5721 184 Human_herpesvirus_2 R-HSA-68882 Mitotic Anaphase 183/4920 201/10654 2.6504160351039917e-42 1.7669440234026613e-40 6.775499638611707e-41 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/5520/51529/4001/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/25936/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/7444/5698/5692/5713/91687/119504/10376/5710/7324/2010/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/7443/1781/7316/10213/4085/55166/5715/5701/5685/8815/5686/79003/9126/9232/23592/5527/9700/5716/701/57551/5693/5721 183 Human_herpesvirus_2 R-HSA-2467813 Separation of Sister Chromatids 174/4920 190/10654 3.8370793508070387e-41 2.441777768695388e-39 9.363207985222918e-40 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/25936/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/5698/5692/5713/91687/119504/10376/5710/7324/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7280/1778/5516/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/1781/7316/10213/4085/55166/5715/5701/5685/5686/79003/9126/9232/5527/9700/5716/701/57551/5693/5721 174 Human_herpesvirus_2 R-HSA-69620 Cell Cycle Checkpoints 244/4920 293/10654 1.879639812073685e-40 1.144128581262243e-38 4.387259973261232e-39 5689/55839/11130/9134/83990/11065/6249/5682/9156/57060/9735/1763/7531/7486/7321/5526/10971/8697/9212/5982/7533/2810/147841/348995/11200/143471/472/57122/5705/1780/23122/5048/5709/4174/5695/57405/8655/84515/23279/4194/4998/5711/2491/4683/10926/5683/990/1060/165918/84126/5699/5702/8900/51529/29945/8924/11004/51434/55388/672/9184/5518/6117/29882/7334/5001/23332/7465/25909/51230/10726/81930/55746/5696/83695/5691/7314/996/5515/5718/6118/79682/10403/23594/25936/5700/122706/5707/51588/51720/3619/23198/63967/898/64105/7534/332/5528/993/116028/890/983/51433/9861/79902/3796/9656/5519/81565/5698/5692/5985/5713/91687/119504/4175/5710/7157/5984/7324/83540/5719/64682/6233/7514/7158/54820/6396/64946/9793/5884/5810/140735/4999/220134/4172/80010/4928/5903/5000/8318/246184/55055/51512/1029/80776/1783/401541/7532/79172/4173/5706/9133/79980/6232/580/8881/11073/891/5501/641/5714/54821/6119/9183/3364/10524/5688/1062/699/5687/144715/5708/22919/5529/51143/1111/10393/5704/23595/7311/25906/5347/84643/5983/5694/4176/7529/1778/5516/1017/5905/81929/5684/5720/54908/55143/5883/5525/25946/1058/991/79019/10111/8317/348235/80152/5690/1063/8379/5717/1027/9491/23421/545/55920/79023/10197/7336/1781/7316/10213/4085/1026/4171/55166/5715/9088/7341/5701/5685/5686/995/79003/5527/5716/701/5932/79184/57551/7156/5693/5721/4193 244 Human_herpesvirus_2 R-HSA-453279 Mitotic G1-G1/S phases 142/4920 149/10654 3.106651147195184e-39 1.812213169197191e-37 6.94908809241028e-38 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/1031/4998/5711/5928/10926/3717/5683/990/5699/5702/5520/8900/55388/28227/1030/5518/6117/5001/7465/5558/5696/5691/7314/5515/6241/5718/6118/25/23594/7027/5700/5707/7153/898/91768/5934/5557/993/890/1876/983/6714/9861/5519/6502/5698/10000/5692/5713/595/4175/5710/896/5719/6233/7298/23649/1719/1163/1859/4999/4172/26271/1019/5000/8318/1029/4173/5706/286826/891/4331/5714/5111/51053/6119/5688/5687/91750/5427/4067/5708/1874/81620/208/5704/55957/23595/7311/5694/4176/5516/1017/894/5684/5720/4605/902/8317/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5933/5426/4171/1871/5715/5701/5685/5686/1021/3065/5716/1022/5693/5721/7083/132660/1028 142 Human_herpesvirus_2 R-HSA-168255 Influenza Life Cycle 138/4920 144/10654 5.261409070425528e-39 2.9463890794382956e-37 1.1298183688071658e-37 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/116832/23225/6156/6143/5439/3836/6139/9972/3921/8021/55746/6208/6170/3303/6203/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/7514/1213/1211/6188/6396/129401/200916/6122/6230/4928/2963/5434/5903/6194/55706/7175/6166/5436/6136/6125/821/6232/6160/5611/6193/6210/4927/6229/6205/2962/140801/6235/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/81929/5440/9349/4736/51121/9631/6159/6217/3843/5430/6152/51065/6141/79023/6123/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 138 Human_herpesvirus_2 R-HSA-168254 Influenza Infection 146/4920 155/10654 1.5998416957738945e-38 8.614532208013278e-37 3.303316861719377e-37 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/116832/23225/6156/6143/5439/3836/6139/9972/3921/8021/7040/55746/6208/6170/3303/6203/402569/6147/6222/8106/9636/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/7514/1213/5610/1211/6188/6396/129401/200916/6122/6230/4928/2963/3838/5434/5903/6194/55706/7175/6166/5436/6136/6125/821/6232/6160/5611/6193/6210/4927/6229/6205/2962/10898/3840/140801/6235/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/81929/5440/9349/4736/51121/9631/6159/6217/3843/5430/6152/51065/6141/79023/6123/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 146 Human_herpesvirus_2 R-HSA-68886 M Phase 305/4920 395/10654 1.0752671761896609e-37 5.575459432094538e-36 2.1379581280964016e-36 114791/10844/23165/5689/55839/11130/11065/440145/6249/5579/5682/9735/7531/1459/11190/7321/91754/203068/5526/54801/51807/8697/5578/9212/347688/10274/5861/5925/1460/147841/348995/79441/143471/10381/57122/5705/5116/1780/23122/23511/5048/5709/5695/57405/8655/1457/23279/9702/5711/2491/10112/7846/23225/7840/5683/1060/5699/9663/11064/5702/5520/51529/4001/29945/11004/23133/51434/9184/9972/5518/55844/55835/29922/8021/29882/23332/84930/25909/10726/81930/55746/93323/5696/5691/7314/996/5515/5718/79682/10403/64151/25936/5700/122706/5707/1454/2801/5594/3619/23198/64105/23310/332/10762/10051/5528/983/8548/51433/9861/79902/3796/8615/79959/5519/9883/81565/2029/7444/5698/5692/5713/80097/91687/119504/10376/23397/5710/10540/85378/7324/2010/83540/64900/5719/64682/6233/23175/7514/54930/54820/113130/9493/6396/129401/1453/27229/64946/9793/140735/220134/84617/4928/26271/5903/55706/7175/11258/22981/246184/55055/8636/80776/1783/401541/7532/55125/10382/79172/121441/7277/5706/9133/79980/25836/6232/23047/8881/9814/653784/5885/23354/891/5501/9738/1639/5714/55722/4957/4927/5566/54821/81876/9183/5688/1062/699/5687/7283/5708/22919/8243/10426/5529/22994/51143/1069/8086/10393/79648/5577/5704/7311/25906/10383/5347/54892/84790/84643/80184/5694/22897/6418/5108/7112/10592/7280/10806/29781/5595/1778/5516/4000/115106/4926/5905/22995/55559/81929/5684/5720/54908/55143/9631/5525/10142/1058/991/79019/348235/80152/5690/1063/8379/95681/5717/9491/23244/23421/55920/79023/23636/10735/10197/7443/1781/7316/10213/80321/10776/53371/26003/4085/9688/55166/10121/5715/84131/5701/5685/3320/8815/5686/79003/9126/9918/10733/4751/9232/23592/5527/9700/27175/80254/5716/701/57551/9662/55142/64689/8481/5693/5721/55755/8480 305 Human_herpesvirus_2 R-HSA-162906 HIV Infection 200/4920 233/10654 3.2685320292227006e-37 1.6342660146113504e-35 6.266734341742772e-36 6884/23165/6875/5689/2237/7852/162/5682/27243/6874/1174/348995/143471/57122/5705/5431/23511/5435/5709/9978/5433/5695/2960/292/567/23279/5711/23327/29082/23225/5683/2965/2534/27183/5699/5439/5702/6873/3836/163/9972/6881/2967/51616/8021/11198/904/55690/51497/5062/55746/5696/5691/7314/5879/5718/8945/51606/161/5700/122706/5707/2959/10053/23198/404672/10015/91782/5438/3978/10762/4836/926/9397/9861/79902/9883/89853/83860/5698/5692/5713/5710/2068/5902/5478/5719/6233/7514/1025/3932/6396/129401/6883/7936/1175/6829/8907/2957/25920/1173/4928/2963/5434/5903/55706/7175/79643/5436/6878/4869/5706/160/920/4331/5714/4927/8148/2966/2962/5688/54457/8812/5687/5708/128866/905/2071/5901/8086/5704/7311/93343/6880/6908/7251/8905/5694/1104/2547/6882/2961/5432/22916/1234/6877/5905/3837/6917/81929/5440/164/5684/8065/5720/902/9631/3159/5430/5690/7520/5717/9491/6500/6749/79023/5441/23636/10197/7469/919/130340/4686/7316/10213/6872/53371/3055/9688/8731/9150/6879/5715/9525/5701/2958/5437/5685/8815/5686/6827/2968/5716/375/138474/1022/5693/5721/8178/8480 200 Human_herpesvirus_2 R-HSA-6807070 PTEN Regulation 133/4920 140/10654 2.3834851384011218e-36 1.1506479978488174e-34 4.4122592398714054e-35 1912/5689/3725/6591/5682/1822/1459/9112/6045/27327/80012/1460/143471/5705/5709/5695/1457/1911/4734/11060/5711/5928/10325/5683/23512/57332/5699/2444/5702/192669/1107/8975/5371/2475/1386/10670/4343/64121/5696/5691/7314/5718/23186/5700/122706/5707/2146/51564/5594/84232/23198/9861/7101/81847/84733/57459/5698/10000/5692/5713/5710/3066/7157/5719/6233/331/8726/26523/7874/57521/23608/6015/28956/389541/9219/8535/5931/58528/5706/5714/1108/2122/64223/10014/5688/5687/5708/54815/6009/208/5704/55004/57504/7311/648/5694/23466/53615/5595/27161/5684/8841/5720/5468/5978/10273/207/5690/57690/5717/9491/10197/192670/153129/7316/10213/57167/5715/1958/5701/5685/8649/5686/5728/6615/3065/23028/5987/23112/10542/5716/5693/5721 133 Human_herpesvirus_2 R-HSA-69206 G1/S Transition 126/4920 131/10654 3.2393333975010365e-36 1.511688918833817e-34 5.796701869212381e-35 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/4998/5711/5928/10926/5683/990/5699/5702/8900/55388/28227/5518/6117/5001/7465/5558/5696/5691/7314/5515/6241/5718/6118/23594/7027/5700/5707/898/91768/5934/5557/993/890/1876/983/9861/5519/6502/5698/10000/5692/5713/595/4175/5710/5719/6233/7298/23649/1719/1163/4999/4172/26271/1019/5000/8318/4173/5706/286826/891/4331/5714/5111/51053/6119/5688/5687/91750/5427/5708/1874/81620/208/5704/55957/23595/7311/5694/4176/5516/1017/5684/5720/902/8317/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5933/5426/4171/5715/5701/5685/5686/3065/5716/1022/5693/5721/7083/132660 126 Human_herpesvirus_2 R-HSA-168273 Influenza Viral RNA Transcription and Replication 128/4920 134/10654 8.883391316361802e-36 4.011854142873072e-34 1.5383801600490725e-34 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/116832/23225/6156/6143/5439/6139/9972/3921/8021/55746/6208/6170/6203/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/6188/6396/129401/200916/6122/6230/4928/2963/5434/5903/6194/55706/7175/6166/5436/6136/6125/6232/6160/5611/6193/6210/4927/6229/6205/2962/140801/6235/6181/8086/7311/6223/25873/9045/6187/5432/6168/6157/6137/6144/81929/5440/9349/4736/51121/9631/6159/6217/3843/5430/6152/51065/6141/79023/6123/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 128 Human_herpesvirus_2 R-HSA-8856828 Clathrin-mediated endocytosis 137/4920 146/10654 1.1053910141948499e-35 4.836085687102469e-34 1.854438872497939e-34 5869/374/85439/71/8674/5286/4738/7039/1212/23208/1785/29763/950/8871/10094/554/54874/10980/22848/7037/2017/3482/408/9322/10987/6456/185/8976/30011/2885/163/11037/1759/23149/3312/29993/9185/7314/9856/1839/161/7018/25977/5868/10618/10093/8027/1856/9892/8322/2060/2069/1601/6453/55707/8301/1129/9146/6455/4074/10920/26119/6233/90019/7474/6844/1213/2580/1211/29924/4036/255324/1175/85021/10109/6869/1173/6857/84251/23048/9026/29988/409/112574/382/160/338/8218/920/22905/26052/8867/10092/9829/2873/10097/7311/1956/60/8533/274/51429/8673/3092/50618/51138/9318/685/127833/1080/29978/58513/7316/1950/273/64708/10552/26130/3267/3949/867/9341/915/917/6572/115548/5878/10096/143425/3575/6845/551/154/10254/6457/4952/11252 137 Human_herpesvirus_2 R-HSA-72613 Eukaryotic Translation Initiation 116/4920 119/10654 2.5689284526100465e-35 1.0577940687217839e-33 4.056202819910599e-34 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/116832/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/1978/200916/6122/1968/6230/8669/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/8893/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/8891/51121/6159/6217/6152/51065/6141/10480/6123/1967/6164/8661/9669/6209/1964/11224/6165/6130/8890/6204/6228/6124/3646/6189/6135/6201/6161/8892/6133 116 Human_herpesvirus_2 R-HSA-72737 Cap-dependent Translation Initiation 116/4920 119/10654 2.5689284526100465e-35 1.0577940687217839e-33 4.056202819910599e-34 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/116832/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/1978/200916/6122/1968/6230/8669/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/8893/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/8891/51121/6159/6217/6152/51065/6141/10480/6123/1967/6164/8661/9669/6209/1964/11224/6165/6130/8890/6204/6228/6124/3646/6189/6135/6201/6161/8892/6133 116 Human_herpesvirus_2 R-HSA-376176 Signaling by ROBO receptors 187/4920 218/10654 9.126056524029828e-35 3.650422609611931e-33 1.3997861134602141e-33 6158/5689/6138/6227/7852/6206/6234/6191/6128/5682/6132/57522/10298/6129/6176/5578/6224/6146/6154/26986/143471/6202/5705/6169/23122/5709/6175/9978/6218/5695/65109/6173/6167/5711/116832/1605/5683/6156/5699/6143/9495/5702/6139/10487/8440/3921/23332/5062/6208/5696/6170/5691/7314/5879/6387/5718/25/6203/8861/6147/5700/122706/5707/5567/6222/23198/27/2935/6134/6091/22794/6155/4116/6714/6231/9861/6142/23521/10486/5698/5692/5713/1981/5710/6207/5719/6233/6188/200916/6122/6230/6194/2107/6166/56924/6136/5568/6125/5706/6232/6160/55110/5714/6193/6210/6229/6205/5566/4650/5688/5687/5708/23767/5063/140801/6235/6181/998/9939/6654/5704/7311/6223/25873/387/6655/23708/5694/5058/9045/6187/6168/22916/6157/6137/10921/6144/55740/23032/5684/9349/4736/5720/51121/2817/6159/4690/6217/6152/5690/5532/5717/9491/51065/6141/6123/10197/6164/4686/7316/10213/5216/6209/11224/6165/6130/5715/6204/5701/6228/5576/5685/5686/7408/6124/8453/5716/23380/1630/6189/9775/6135/6201/6161/5693/5721/6133 187 Human_herpesvirus_2 R-HSA-8957275 Post-translational protein phosphorylation 106/4920 108/10654 2.5346146996043146e-33 9.856834942905667e-32 3.779688587129241e-32 56955/4240/3270/9210/10272/2153/7857/29106/91851/6696/51156/1435/265/11098/10130/2200/80341/375056/1114/720/10117/3956/3569/54972/2519/8720/7018/10618/11167/813/5179/8074/51246/348/4924/3484/102/8614/336/6694/4148/174/57104/721/2335/7466/116519/2266/51280/7076/2243/84141/3488/8542/4221/351/4052/7184/56975/334/3912/338/64856/335/5611/197/3053/3895/5624/1000/54757/8404/255738/3913/652/57719/147111/2719/3487/3371/54587/401138/3486/7425/6383/3827/3490/5589/2621/3915/5768/1471/1462/10232/462/3698/5265/1758/258/11320/5954/213/10970/5034/1356/718 106 Human_herpesvirus_2 R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 109/4920 112/10654 5.206288465411161e-33 1.9699469869123312e-31 7.553932055077361e-32 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/6202/6169/6175/6218/6173/6167/116832/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/200916/6122/1968/6230/8669/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/9669/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 109 Human_herpesvirus_2 R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 108/4920 111/10654 1.1103738859031053e-32 4.090851158590389e-31 1.5686722487827802e-31 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/116832/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/200916/6122/1968/6230/8669/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 108 Human_herpesvirus_2 R-HSA-69239 Synthesis of DNA 114/4920 119/10654 2.4741597750724214e-32 8.881599192567666e-31 3.405726006172564e-31 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/143471/5705/5709/5422/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/6117/29882/5001/10714/5558/5696/5691/7314/996/5718/6118/23594/5700/122706/5707/23198/898/3978/5557/890/51433/9861/6502/5698/5692/5985/5713/119504/4175/5710/5984/7324/5719/64682/6233/23649/5424/4999/4172/5000/8318/246184/4173/5706/8881/5425/5714/5111/6119/5688/5687/5427/5708/81620/10393/5704/51343/23595/7311/25906/51659/5983/5694/4176/1017/5684/5720/57804/9837/5690/5717/9491/6500/10197/7316/10213/5426/4171/5715/5701/5685/5686/5716/5981/5693/5721 114 Human_herpesvirus_2 R-HSA-69306 DNA Replication 120/4920 127/10654 3.2649685153232854e-32 1.14273898036315e-30 4.381931428460198e-31 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/143471/5705/5709/5422/9978/1869/4174/5695/84515/4998/5711/10926/5683/990/5699/5702/8900/51529/29945/51434/55388/6117/29882/5001/10714/5558/5696/5691/7314/996/5718/6118/23594/5700/122706/5707/23198/898/3978/5557/890/51433/9861/6502/5698/5692/5985/5713/119504/4175/5710/5984/7324/5719/64682/6233/23649/5424/4999/4172/5000/8318/246184/4173/5706/8881/5425/5714/5111/51053/6119/5688/5687/5427/5708/81620/10393/5704/51343/23595/7311/25906/51659/5983/5694/4176/1017/5684/5720/57804/8317/9837/5690/5717/9491/6500/10197/7316/10213/5426/4171/1871/5715/5701/5685/5686/5716/5981/5693/5721 120 Human_herpesvirus_2 R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 124/4920 134/10654 9.458115432484842e-31 3.2296003915801903e-29 1.2384181952675915e-29 5295/8454/5689/3725/4893/5335/4790/5682/5291/7321/143471/5705/5530/5709/5695/4792/5711/5683/2534/5699/5702/2885/9846/3845/7334/3265/3551/5062/5696/5691/7314/5879/257397/5718/8945/5601/4773/5290/5700/122706/5707/5336/5594/4214/23198/23118/8517/10125/5970/9861/5588/5698/5692/5713/5710/10454/5719/6233/7410/7409/3702/2353/115727/801/805/5170/6464/2205/4772/3937/4775/10451/5706/2206/6850/8915/5714/5688/5687/4067/5708/5602/695/7189/6654/5704/7311/5694/5058/6416/997/5595/1147/9402/5684/5720/6885/5690/5532/5717/9491/6500/3708/10197/7316/10213/10768/7322/5715/5701/27040/23291/5685/5686/5534/5609/5716/10235/5296/808/5599/5693/5721/2207 124 Human_herpesvirus_2 R-HSA-9010553 Regulation of expression of SLITs and ROBOs 150/4920 171/10654 1.9170162944506085e-30 6.390054314835362e-29 2.4503215793729584e-29 6158/5689/6138/6227/6206/6234/6191/6128/5682/6132/6129/6176/6224/6146/6154/26986/143471/6202/5705/6169/5709/6175/9978/6218/5695/65109/6173/6167/5711/116832/1605/5683/6156/5699/6143/5702/6139/3921/6208/5696/6170/5691/7314/5718/6203/8861/6147/5700/122706/5707/6222/23198/2935/6134/6091/22794/6155/4116/6231/9861/6142/23521/5698/5692/5713/1981/5710/6207/5719/6233/6188/200916/6122/6230/6194/2107/6166/6136/6125/5706/6232/6160/55110/5714/6193/6210/6229/6205/5688/5687/5708/140801/6235/6181/9939/5704/7311/6223/25873/23708/5694/9045/6187/6168/22916/6157/6137/10921/6144/23032/5684/9349/4736/5720/51121/6159/6217/6152/5690/5717/9491/51065/6141/6123/10197/6164/4686/7316/10213/6209/11224/6165/6130/5715/6204/5701/6228/5685/5686/6124/8453/5716/6189/9775/6135/6201/6161/5693/5721/6133 150 Human_herpesvirus_2 R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 91/4920 92/10654 9.360059939894968e-30 3.047461375779757e-28 1.1685754147726887e-28 6884/6875/5563/83990/9156/1763/1459/7486/6874/9212/5982/1460/11200/472/53632/28996/1457/6790/4194/1432/4683/84126/8900/6873/672/6881/51616/6117/11198/83695/7314/1263/6118/51422/116028/890/83860/5985/7157/5984/6233/5600/6883/5884/5810/26155/80010/8445/204851/6878/580/11073/641/8148/6119/3364/5571/10524/54457/144715/6794/94241/1111/7311/5562/6880/6908/5983/5564/6882/5565/1020/6877/1017/9891/5883/10111/22974/6749/545/8550/7316/6872/6879/112858/5932/8851/5300/7156/138474/4193 91 Human_herpesvirus_2 R-HSA-72689 Formation of a pool of free 40S subunits 98/4920 101/10654 2.1184506387192205e-29 6.740524759561155e-28 2.5847125017866088e-28 6158/6138/6227/6206/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/8663/23521/6207/6233/51386/6188/200916/6122/6230/8669/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/8664/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 98 Human_herpesvirus_2 R-HSA-69052 Switching of origins to a post-replicative state 89/4920 90/10654 4.3797973721166893e-29 1.3626036268807477e-27 5.225021426384822e-28 8454/5689/9134/11065/5682/7321/8697/143471/5705/5709/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/29882/5001/5696/5691/7314/996/5718/23594/5700/122706/5707/23198/898/890/51433/9861/6502/5698/5692/5713/119504/4175/5710/7324/5719/64682/6233/4999/4172/5000/246184/4173/5706/8881/5714/5688/5687/5708/81620/10393/5704/51343/23595/7311/25906/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 89 Human_herpesvirus_2 R-HSA-418594 G alpha (i) signalling events 296/4920 406/10654 7.893119157853726e-29 2.4022536567380903e-27 9.211649360424256e-28 729230/2788/10316/1880/7852/50833/29899/2339/5331/5726/338442/64805/2770/817/1237/2550/5578/50832/3354/2841/4987/51289/259294/8644/2912/3576/6360/5530/4985/2920/2921/1236/259295/107/9568/2840/2831/5367/4988/6370/58191/5475/6755/1524/643/2782/5499/339403/4023/2914/8843/2847/2833/9290/5518/9170/6382/187/6750/6004/259296/259289/5998/50835/2587/53829/814/2773/5515/2787/6387/54884/818/4544/4543/126006/10663/4889/9283/727/338398/117579/3579/375790/23566/2358/5567/2916/259293/5594/5179/10681/112/8811/5573/348/56923/2832/5528/27199/2826/6376/165140/27198/111/5443/4836/3627/2792/9397/54429/6714/336/3361/6346/10988/5519/134/5588/1129/51083/2785/2783/2784/1233/6366/2861/2771/728/183/10022/5580/6373/57121/1132/1814/80835/4036/5153/6357/50700/196883/9672/115/8698/5999/801/9934/50840/2791/50865/805/10803/2913/3838/7276/351/11251/3352/8484/6351/6752/1903/84539/6753/5568/3577/2918/5368/6754/8862/301/56670/150/113/338/335/2853/6751/186/53637/10645/5566/84254/10563/5540/1901/5733/23236/256933/10850/624/4852/816/2786/50838/5577/5473/4283/11255/10874/83756/51109/2719/56477/1020/259286/3350/129521/1234/109/5516/151/57007/5533/815/26086/5321/9294/54331/283869/2817/5575/59345/63940/4986/6374/5539/259287/2852/50836/1230/5532/846/4886/2919/51764/94235/114/3708/259290/57016/6383/108/5196/2779/3827/5173/2357/55970/2778/6352/140/10768/346562/152/6364/80834/259292/3949/2793/5030/5697/5576/3355/5534/3351/4035/6288/6372/50834/259285/79823/1385/7804/719/6363/2917/1268/50831/2359/50839/808/5660/1815/1325/1232/1902/50837/5137/1269/59340/4887/2790/718/623 296 Human_herpesvirus_2 R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 103/4920 108/10654 8.450169029774592e-29 2.517071625890304e-27 9.651928791007931e-28 5295/3605/7124/2308/1052/7291/356/3593/9021/6624/3082/5743/3091/10538/3383/6097/6657/3576/3662/3688/4985/7133/3606/4609/4988/3717/6347/7040/3312/3569/4692/3596/3598/3592/7412/4582/6367/4312/6778/332/4313/3565/3934/3976/5443/3718/149233/598/2247/2335/595/7157/2353/604/7076/51561/3570/7297/9655/3566/7184/3684/4318/3726/58480/301/6774/6772/8651/1901/3552/79923/112744/3716/6356/5008/3586/6095/596/2208/2309/3561/207/5292/5451/7422/3553/2625/3597/4314/1026/3320/4843/6288/948/6935/3687/7431/3929/3162/1278/4170/3689 103 Human_herpesvirus_2 R-HSA-5620912 Anchoring of the basal body to the plasma membrane 95/4920 98/10654 2.026933543330297e-28 5.911889501380033e-27 2.266965147145727e-27 79867/7531/11190/203068/54801/85302/79441/5116/5048/22832/8655/9702/132320/7846/7840/11064/84902/5518/55835/23332/93323/1454/54806/91147/983/79959/10540/117177/57545/26005/54930/54820/23322/1453/9793/4218/11258/22981/8636/54903/80776/7532/55125/10382/121441/7277/9814/23354/146057/9738/1639/55722/4957/5566/7283/22919/27077/22994/4867/1069/5577/10383/5347/80184/22897/5108/261734/57787/10806/9657/1778/115106/22995/55559/10142/51134/95681/1781/80321/8766/79598/10121/347240/84131/3320/79600/10733/4751/80254/26123/9662/55142/8481/51259/55755 95 Human_herpesvirus_2 R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 115/4920 125/10654 5.410944414626314e-28 1.5459841184646612e-26 5.928209777571256e-27 56955/4240/3270/9210/10272/2153/1511/7857/29106/91851/6696/51156/1435/265/11098/10130/2200/80341/375056/1114/720/10117/3956/3569/54972/2519/8720/7018/5340/10618/11167/813/5179/8074/4312/51246/348/4924/4313/3484/102/8614/336/6694/4148/174/57104/721/2335/7466/116519/2266/51280/7076/2243/60676/84141/3488/8542/4221/351/4052/7184/56975/334/3912/338/64856/335/5611/197/3053/3895/5624/1000/54757/3481/8404/255738/3913/652/57719/147111/2719/3487/3371/54587/3485/3489/401138/3486/7425/6383/3827/3490/5589/2621/3915/5768/1471/1462/10232/462/3698/5265/1758/258/11320/5954/3479/213/10970/5034/1356/718 115 Human_herpesvirus_2 R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 85/4920 86/10654 9.56265583568504e-28 2.625042778423344e-26 1.0065953511247411e-26 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 85 Human_herpesvirus_2 R-HSA-453276 Regulation of mitotic cell cycle 85/4920 86/10654 9.56265583568504e-28 2.625042778423344e-26 1.0065953511247411e-26 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 85 Human_herpesvirus_2 R-HSA-69618 Mitotic Spindle Checkpoint 105/4920 112/10654 1.7179704840968006e-27 4.625305149491386e-26 1.7736132528124862e-26 55839/11130/11065/6249/9735/7321/5526/8697/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/996/5515/79682/10403/25936/3619/64105/332/5528/51433/79902/3796/5519/81565/91687/119504/7324/83540/64682/7514/54820/6396/64946/9793/140735/220134/4928/5903/246184/55055/80776/1783/401541/79172/79980/6232/8881/5501/54821/9183/1062/699/22919/5529/51143/10393/25906/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/55166/79003/5527/701/57551 105 Human_herpesvirus_2 R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 92/4920 95/10654 1.9319543773434578e-27 5.1032757137374357e-26 1.956895198500821e-26 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/2935/6134/6155/6231/6142/23521/1981/6207/6233/6188/5976/200916/6122/6230/6194/2107/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/23708/9045/6187/6168/22916/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/4686/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 92 Human_herpesvirus_2 R-HSA-162909 Host Interactions of HIV factors 117/4920 129/10654 4.982133786192032e-27 1.291664314938675e-25 4.9529985008926634e-26 23165/5689/162/5682/1174/348995/143471/57122/5705/23511/5709/9978/5695/292/567/23279/5711/23225/5683/2534/5699/5702/3836/163/9972/8021/904/55690/5062/55746/5696/5691/7314/5879/5718/8945/51606/161/5700/122706/5707/10053/23198/10762/926/9861/79902/9883/5698/5692/5713/5710/5902/5478/5719/6233/7514/1025/3932/6396/129401/1175/8907/1173/4928/5903/55706/7175/4869/5706/160/920/5714/4927/5688/5687/5708/5901/8086/5704/7311/8905/5694/1104/5905/3837/81929/164/5684/8065/5720/9631/3159/5690/5717/9491/6500/79023/23636/10197/919/130340/7316/10213/53371/3055/9688/5715/5701/5685/8815/5686/5716/375/5693/5721/8480 117 Human_herpesvirus_2 R-HSA-156842 Eukaryotic Translation Elongation 90/4920 93/10654 8.665742598206305e-27 2.2058253886343323e-25 8.458428181981274e-26 6158/6138/6227/6206/6234/6191/6128/6132/1917/6129/1915/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6166/1938/6136/6125/1937/6232/6160/1933/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/1936/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 90 Human_herpesvirus_2 R-HSA-927802 Nonsense-Mediated Decay (NMD) 106/4920 115/10654 4.568390553423593e-26 1.1220608376829877e-24 4.302639302393411e-25 6158/9887/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/65109/6173/6167/116832/6156/6143/5520/6139/23381/5518/3921/6208/6170/5515/6203/6147/6222/2935/6134/22794/6155/4116/6231/6142/23521/1981/6207/6233/6188/23049/5976/200916/6122/6230/6194/2107/6166/6136/6125/6232/6160/55110/6193/6210/6229/6205/140801/6235/6181/9939/7311/6223/25873/23708/9045/6187/6168/22916/6157/6137/10921/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/4686/6209/11224/6165/6130/6204/6228/6124/6189/23293/9775/6135/6201/6161/6133 106 Human_herpesvirus_2 R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 106/4920 115/10654 4.568390553423593e-26 1.1220608376829877e-24 4.302639302393411e-25 6158/9887/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/65109/6173/6167/116832/6156/6143/5520/6139/23381/5518/3921/6208/6170/5515/6203/6147/6222/2935/6134/22794/6155/4116/6231/6142/23521/1981/6207/6233/6188/23049/5976/200916/6122/6230/6194/2107/6166/6136/6125/6232/6160/55110/6193/6210/6229/6205/140801/6235/6181/9939/7311/6223/25873/23708/9045/6187/6168/22916/6157/6137/10921/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/4686/6209/11224/6165/6130/6204/6228/6124/6189/23293/9775/6135/6201/6161/6133 106 Human_herpesvirus_2 R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 79/4920 80/10654 9.683830324103986e-26 2.3374762851285484e-24 8.96325492793654e-25 8454/5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 79 Human_herpesvirus_2 R-HSA-913531 Interferon Signaling 163/4920 199/10654 1.0282105155708747e-25 2.4241737277985426e-24 9.29570376825005e-25 80263/3443/23165/201626/5777/5335/960/5770/3107/817/9021/348995/317649/3383/57122/11274/3662/23511/4684/567/4734/6672/3113/23279/3106/8672/3459/3717/23225/1973/3836/5371/4599/684/9972/3133/3429/8021/3127/91543/7334/4938/4261/55746/5696/7314/3445/818/402569/115362/7412/10410/9830/9636/2634/3444/10762/2317/103/3434/3433/79902/23586/9883/3451/3448/1981/10612/3458/3661/7324/1977/3439/51191/6233/5580/81603/5610/10581/3452/4940/6396/3437/129401/6773/7297/5781/3430/3660/3446/8554/3135/3665/4928/3838/5903/10379/55706/7175/3455/2316/2633/4600/3123/2209/8638/25820/1982/7706/9470/3122/3394/3663/6772/8651/4927/3659/3840/25939/3440/5771/3454/816/8086/10346/9246/3716/7311/3456/3105/1974/5595/3460/815/3837/81929/3441/6737/51447/9631/4281/54739/79023/2537/23636/3449/7316/53371/8519/3664/9688/6041/1958/4939/7341/6059/3669/3134/5300/9775/5495/5724/8480 163 Human_herpesvirus_2 R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 83/4920 85/10654 1.038931597627947e-25 2.4241737277985426e-24 9.29570376825005e-25 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/91768/5934/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/1163/1019/5706/286826/4331/5714/5688/5687/91750/5708/1874/208/5704/55957/51343/7311/5694/1017/5684/994/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5715/5701/5685/5686/5716/1022/5693/5721/132660 83 Human_herpesvirus_2 R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 99/4920 106/10654 1.2743804711156143e-25 2.9248076386259996e-24 1.121542778721248e-24 374/85439/8674/4738/7039/1212/23208/950/554/10980/22848/7037/3482/408/10987/6456/185/30011/2885/163/11037/23149/9185/7314/9856/1839/161/7018/25977/10618/8027/1856/9892/8322/2060/2069/1601/6453/55707/8301/1129/9146/6455/4074/10920/26119/6233/90019/7474/6844/1213/1211/29924/4036/255324/1175/85021/6869/1173/6857/84251/29988/409/160/338/8218/920/22905/2873/7311/1956/8533/8673/50618/51138/9318/685/127833/1080/29978/58513/7316/1950/64708/3267/3949/867/9341/915/917/6572/115548/143425/3575/6845/551/154/10254/6457 99 Human_herpesvirus_2 R-HSA-156902 Peptide chain elongation 86/4920 89/10654 1.7338018266744152e-25 3.915036382813196e-24 1.5012545528080674e-24 6158/6138/6227/6206/6234/6191/6128/6132/6129/1915/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6166/1938/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 86 Human_herpesvirus_2 R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 85/4920 88/10654 3.662459579134005e-25 8.138799064742232e-24 3.120892874450029e-24 8454/7531/11190/203068/54801/79441/5116/5048/8655/6790/9702/7846/7840/11064/5518/55835/23332/93323/7314/8945/4659/1454/983/79959/10540/6233/54930/54820/1453/9793/4218/5500/11258/22981/8636/7532/84962/55125/10382/121441/7277/9133/9814/23354/891/9738/1639/55722/4957/5566/7283/22919/22994/79866/1069/5577/7311/10133/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/6500/1781/7316/80321/10121/84131/23291/3320/10733/4751/80254/9662/55142/8481/55755 85 Human_herpesvirus_2 R-HSA-69202 Cyclin E associated events during G1/S transition 81/4920 83/10654 4.728970698271018e-25 1.034462340246785e-23 3.966735289668123e-24 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/91768/5934/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/1163/1019/5706/286826/4331/5714/5688/5687/91750/5708/1874/208/5704/55957/7311/5694/1017/5684/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5715/5701/5685/5686/5716/1022/5693/5721/132660 81 Human_herpesvirus_2 R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 80/4920 82/10654 1.008318016834912e-24 2.138856399346783e-23 8.201629802006461e-24 114791/10844/440145/7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/1454/983/79959/80097/10540/85378/54930/54820/1453/27229/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/728642/9738/1639/55722/4957/5566/7283/22919/984/10426/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 80 Human_herpesvirus_2 R-HSA-380287 Centrosome maturation 80/4920 82/10654 1.008318016834912e-24 2.138856399346783e-23 8.201629802006461e-24 114791/10844/440145/7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/1454/983/79959/80097/10540/85378/54930/54820/1453/27229/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/728642/9738/1639/55722/4957/5566/7283/22919/984/10426/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 80 Human_herpesvirus_2 R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 75/4920 76/10654 2.0928787688456656e-24 4.373179516990943e-23 1.676933498996527e-23 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 75 Human_herpesvirus_2 R-HSA-192823 Viral mRNA Translation 85/4920 89/10654 4.464643681890115e-24 9.1494831350446e-23 3.5084484202050714e-23 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/5611/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 85 Human_herpesvirus_2 R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 74/4920 75/10654 4.509388116557695e-24 9.1494831350446e-23 3.5084484202050714e-23 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 74 Human_herpesvirus_2 R-HSA-72764 Eukaryotic Translation Termination 88/4920 93/10654 4.98162644486552e-24 9.963252889731039e-23 3.8204954689946084e-23 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/2935/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/2107/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/23708/9045/6187/6168/6157/6137/6144/9349/4736/327/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 88 Human_herpesvirus_2 R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 151/4920 185/10654 1.3426680431844366e-23 2.647514451349593e-22 1.0152123084122499e-22 6158/5393/6138/6227/6206/6234/6191/6128/6132/6129/23404/6176/10528/84135/27340/27043/6224/6146/6154/88745/6202/51096/6169/55272/6175/6218/5394/6173/6167/116832/23481/51077/6156/117246/6143/6139/23160/26168/11340/3921/10607/11103/6208/6170/22984/10813/9136/6203/6147/8568/6222/1454/56902/51602/6134/6155/9724/6231/6142/23521/54555/10171/5822/6207/10969/6233/6188/54881/1453/4691/23016/200916/6122/6230/2091/55127/8602/6194/6166/10436/9277/84128/6136/6125/6232/134430/6160/92856/65083/6193/10200/6210/6229/6205/11056/9790/140801/6235/55720/6181/7311/6223/25873/51010/26354/56915/51202/9045/57647/6187/6168/6157/6137/79050/22894/6144/9349/55813/4736/22803/51121/6159/25879/6217/81887/6152/57050/51065/6141/6123/55781/6164/6209/11224/6165/6130/6204/6228/10199/6124/25926/83732/27341/6189/6135/6201/6161/54512/10885/6133/9188 151 Human_herpesvirus_2 R-HSA-2262752 Cellular responses to stress 327/4920 479/10654 1.62547824524893e-23 3.160652143539586e-22 1.21197939338736e-22 1912/23165/5689/3725/9134/11065/573/4790/5682/7531/1915/7321/51807/817/6045/8697/9530/347688/23677/27327/80012/7295/5925/3091/348995/143471/472/10381/57122/5705/79813/3576/3313/1780/7001/23511/10312/5709/9978/2114/1869/5695/3305/8655/1911/832/23279/4194/1031/5711/5928/1432/1387/4683/10325/7846/23225/5683/3309/23512/57332/5699/7428/5702/192669/9531/8900/51529/4001/29945/8091/8131/2056/51434/2475/3306/1030/6196/9972/10670/23411/8021/4343/6117/10587/6197/29882/3312/4217/3569/64121/55746/5696/5691/7296/7314/51164/996/51182/5718/818/3303/7014/6118/51606/5601/5606/7027/5700/122706/5707/2146/9550/9114/5594/3308/84335/23198/898/10049/10013/27244/3337/10762/7323/890/5970/9261/6667/51433/9861/79902/5598/9883/2932/84733/5698/5692/5713/2877/119504/10376/6195/5710/3301/10540/7157/7324/5719/64682/6233/2353/538/8726/6396/129401/5600/26523/528/405/5608/3297/57521/140735/768/6015/28956/84617/4928/1019/5903/83667/55706/7175/653361/5241/11258/9448/246184/112399/1029/1783/389541/8535/84962/10382/5931/58528/10294/55860/830/7013/7277/1051/1410/50488/5706/10671/8881/527/6774/1639/5714/4927/7867/64223/6119/3552/10370/10524/5688/5687/57805/3310/2908/5708/5602/7266/25824/6009/51143/816/6648/8086/10393/5704/3326/55004/51343/7311/367/25906/2034/57634/10383/84790/55662/648/5694/3304/23466/3456/2113/6416/10641/7280/10728/829/23523/5595/1778/1017/815/25913/81929/5684/5720/9631/3159/7290/10111/7422/5690/57690/5717/1027/9491/545/79023/23636/10197/192670/10808/153129/3490/8550/29855/1781/7316/10213/53371/1026/9532/54205/2289/9588/9688/10121/7415/1871/6647/8994/7322/5715/5701/245972/144577/5685/8649/3320/5686/2033/1021/6767/25842/8453/23135/10963/22824/23112/5609/10542/5716/9529/5599/54583/5052/5693/5721/2288/5034/8480/10919/51382/2950/4193/23043 327 Human_herpesvirus_2 R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72/4920 73/10654 2.0916575307347852e-23 4.0113980041489026e-22 1.5382052497112333e-22 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/5716/701/5693/5721 72 Human_herpesvirus_2 R-HSA-8868773 rRNA processing in the nucleus and cytosol 157/4920 195/10654 2.800050808307422e-23 5.297393421122151e-22 2.0313313118588695e-22 6158/5393/6138/6227/6206/6234/6191/6128/6132/6129/23404/55226/6176/10528/84135/27340/27043/6224/6146/6154/88745/6202/51096/6169/55272/6175/6218/5394/6173/6167/116832/23481/51077/6156/117246/6143/6139/23160/26168/11340/3921/10607/11103/6208/6170/22984/10813/9136/6203/6147/8568/27292/6222/1454/56902/51602/6134/6155/9724/6231/6142/23521/54555/10171/5822/6207/10969/6233/6188/54881/1453/4691/23016/200916/6122/6230/2091/55651/55127/8602/6194/6166/10436/9277/84128/6136/6125/4839/6232/134430/6160/92856/65083/6193/10200/6210/6229/6205/11056/9790/140801/6235/55720/6181/7311/6223/25873/55505/51010/26354/56915/51202/9045/57647/6187/6168/6157/6137/79050/22894/6144/9349/55813/4736/22803/51121/6159/25879/6217/81887/6152/57050/51065/6141/6123/55781/6164/6209/11224/6165/6130/6204/1736/6228/10199/6124/25926/83732/27341/6189/6135/6201/6161/54512/10885/6133/9188 157 Human_herpesvirus_2 R-HSA-2500257 Resolution of Sister Chromatid Cohesion 111/4920 126/10654 3.5769204534925227e-23 6.676918179852709e-22 2.5603220088157004e-22 55839/11130/6249/9735/5526/51807/9212/347688/10274/147841/348995/10381/57122/1780/23122/5048/57405/8655/23279/2491/7846/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/983/79902/3796/5519/81565/91687/10376/83540/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/55055/80776/1783/401541/10382/79172/7277/9133/79980/6232/23047/5885/891/5501/54821/9183/1062/699/22919/8243/5529/51143/10383/5347/84790/84643/7280/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23244/23421/55920/79023/10735/1781/4085/55166/79003/9126/5527/701/57551 111 Human_herpesvirus_2 R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 71/4920 72/10654 4.5028334448479287e-23 8.082008747162949e-22 3.099116136130153e-22 5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 71 Human_herpesvirus_2 R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 71/4920 72/10654 4.5028334448479287e-23 8.082008747162949e-22 3.099116136130153e-22 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 71 Human_herpesvirus_2 R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 71/4920 72/10654 4.5028334448479287e-23 8.082008747162949e-22 3.099116136130153e-22 5689/9134/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/990/5699/5702/8900/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/898/890/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/1017/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 71 Human_herpesvirus_2 R-HSA-6802957 Oncogenic MAPK signaling 70/4920 71/10654 9.69060409245208e-23 1.6958557161791137e-21 6.502905377829685e-22 4893/71/817/5908/55109/54845/8546/22866/5605/5037/3717/10827/2244/3690/408/4296/5894/8826/1185/4140/3845/3265/4763/818/8805/55750/8844/7094/5594/7414/10533/23164/57085/6714/9061/2335/1445/2266/2243/369/801/57670/805/283455/3674/409/673/8315/816/56829/7450/60/9444/7529/5595/4000/27044/815/22906/8087/5604/10018/10142/54518/80853/10256/5906/808/9715/5245 70 Human_herpesvirus_2 R-HSA-68949 Orc1 removal from chromatin 70/4920 71/10654 9.69060409245208e-23 1.6958557161791137e-21 6.502905377829685e-22 8454/5689/5682/143471/5705/5709/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/890/9861/6502/5698/5692/5713/4175/5710/5719/6233/4999/4172/5000/4173/5706/5714/5688/5687/5708/81620/5704/23595/7311/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 70 Human_herpesvirus_2 R-HSA-8878166 Transcriptional regulation by RUNX2 107/4920 121/10654 1.107396274268616e-22 1.914018251822299e-21 7.339468484431372e-22 8454/8493/5689/7291/5682/5925/143471/5705/5709/9978/5695/9759/10413/4089/5711/5683/2101/1749/5699/5702/5696/5691/7314/5718/25/6662/5700/122706/5707/5594/3280/23198/100526737/10013/2737/865/11059/983/6714/2099/9861/2932/6502/5698/10000/5692/5713/595/5710/5719/6233/7525/10432/133522/117581/1019/3958/5706/3678/1277/891/579/5714/6772/5688/5687/2908/5708/4488/208/5704/23493/7311/367/860/1750/5694/5595/57154/5684/8841/5720/23462/10273/207/5690/5717/9491/6500/4086/10197/7316/10213/4094/1026/5715/5701/5685/5686/55294/23314/861/5716/581/5693/5721/10891 107 Human_herpesvirus_2 R-HSA-5357801 Programmed Cell Death 147/4920 181/10654 1.3807834378838915e-22 2.3574351378505467e-21 9.0397888744645e-22 5689/2339/5682/4976/7531/55075/356/10971/10059/7533/2810/143471/5705/5709/1869/5695/8655/660/5711/836/5683/324/5699/5702/90427/4001/3836/6709/6093/840/7159/26060/637/5062/5696/5691/7314/578/23368/5718/2934/22985/219699/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/100506658/7082/5339/4836/8797/9861/10134/999/5588/598/5698/10000/5692/708/5713/5710/7157/5719/6233/5580/1613/839/8772/331/8717/317/140735/5747/1029/572/7532/330/118/5706/1829/6774/5366/5714/5688/5687/1832/5708/8837/8626/197259/208/5704/7311/7161/5694/8795/3148/7529/5595/4000/5533/27113/3837/596/5684/5720/7186/51765/1499/10018/842/207/5690/5717/9491/355/10197/7099/7316/10213/54205/3146/5715/23604/5701/329/5685/5686/5534/4137/5716/1630/581/5599/7431/5693/5721/6304 147 Human_herpesvirus_2 R-HSA-109581 Apoptosis 145/4920 178/10654 1.522293260551877e-22 2.5677235720152144e-21 9.846158058103453e-22 5689/2339/5682/4976/7531/55075/356/10971/10059/7533/2810/143471/5705/5709/1869/5695/8655/660/5711/836/5683/324/5699/5702/90427/4001/3836/6709/6093/840/7159/26060/637/5062/5696/5691/7314/578/23368/5718/2934/22985/219699/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/100506658/7082/5339/4836/8797/9861/10134/999/5588/598/5698/10000/5692/708/5713/5710/7157/5719/6233/5580/1613/839/8772/331/8717/317/140735/5747/1029/572/7532/118/5706/1829/6774/5366/5714/5688/5687/1832/5708/8837/8626/208/5704/7311/7161/5694/8795/3148/7529/5595/4000/5533/27113/3837/596/5684/5720/7186/51765/1499/10018/842/207/5690/5717/9491/355/10197/7099/7316/10213/54205/3146/5715/23604/5701/329/5685/5686/5534/4137/5716/1630/581/5599/7431/5693/5721/6304 145 Human_herpesvirus_2 R-HSA-141424 Amplification of signal from the kinetochores 89/4920 96/10654 1.5680516857598163e-22 2.5826733647808736e-21 9.90348433111463e-22 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/79902/3796/5519/81565/91687/83540/7514/54820/6396/64946/9793/140735/220134/4928/5903/55055/80776/1783/401541/79172/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/55166/79003/5527/701/57551 89 Human_herpesvirus_2 R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 89/4920 96/10654 1.5680516857598163e-22 2.5826733647808736e-21 9.90348433111463e-22 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/79902/3796/5519/81565/91687/83540/7514/54820/6396/64946/9793/140735/220134/4928/5903/55055/80776/1783/401541/79172/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/55166/79003/5527/701/57551 89 Human_herpesvirus_2 R-HSA-72202 Transport of Mature Transcript to Cytoplasm 80/4920 84/10654 1.759050653755358e-22 2.863570831694769e-21 1.0980609956122798e-21 23165/8683/6431/84271/199746/348995/57122/23511/81608/65109/23279/23225/9877/9972/8021/55746/53981/7919/6432/8563/6430/56001/80145/10762/22794/9785/11338/29107/4116/79902/9883/51213/10250/26097/51362/1977/57187/6396/129401/79228/2733/84324/4928/5903/55706/7175/7884/6428/10212/55110/84321/6429/4927/10898/10569/9295/10482/51692/8086/9939/6426/22916/10921/81929/9631/29894/79023/23636/4686/8189/53371/7307/9688/9984/10189/9775/84248/6427/8480/55339 80 Human_herpesvirus_2 R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 83/4920 88/10654 1.875282900601129e-22 3.0176966216569893e-21 1.157161862439898e-21 5393/5689/5682/23404/5578/26986/143471/5705/5709/5695/5711/1432/5683/5699/5702/11340/8021/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/7534/9261/8741/9861/5698/5692/5713/1981/5710/5719/6233/5580/7514/5600/8570/23016/1994/5073/3842/3315/5706/8125/7538/5714/5688/5687/5708/5704/7311/51010/5694/56915/3304/6418/167227/7529/22894/5684/5720/207/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/54464/5693/54512/5721 83 Human_herpesvirus_2 R-HSA-2219528 PI3K/AKT Signaling in Cancer 92/4920 101/10654 7.878594846077495e-22 1.2534128164214196e-20 4.806319822367849e-21 5295/2308/374/2250/5291/7039/3082/941/2064/145957/2534/9965/2264/9542/2885/2475/8660/2252/2253/5879/1839/5290/3667/8823/2065/3815/2069/84335/8074/7249/2260/2249/6714/2099/2248/2932/2247/10000/7409/2246/2251/5154/3932/2931/255324/5781/253260/5170/572/4303/930/6199/2263/4233/64223/8503/5159/3084/208/10718/79109/5293/1956/2549/1147/8822/685/2309/842/207/1027/8817/2100/2254/152831/1950/1026/26281/10818/2261/2255/3164/5728/2066/27006/942/1385/5155/4254/5296/5156/4193 92 Human_herpesvirus_2 R-HSA-8854518 AURKA Activation by TPX2 71/4920 73/10654 9.009957839586294e-22 1.417296738811327e-20 5.434746893186291e-21 7531/11190/203068/54801/79441/5116/5048/8655/6790/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/22974/3161/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 71 Human_herpesvirus_2 R-HSA-5658442 Regulation of RAS by GAPs 67/4920 68/10654 9.64140775976462e-22 1.49977454040783e-20 5.751015154947318e-21 5689/4893/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/3845/3265/4763/5696/5691/7314/5718/10156/8831/5700/122706/5707/23198/5921/9861/5698/5692/5713/5710/5719/6233/200734/22821/9462/5706/84078/5714/64926/5688/5687/5708/5704/7311/5694/5684/5720/153090/5690/5717/9491/10197/7316/10213/5715/8437/5701/5922/5685/5686/5716/399473/5693/5721/161742 67 Human_herpesvirus_2 R-HSA-72312 rRNA processing 161/4920 205/10654 1.0356605794752106e-21 1.593323968423401e-20 6.109738525533341e-21 6158/5393/6138/6227/6206/6234/6191/6128/6132/6129/23404/55226/6176/10528/84135/27340/27043/6224/6146/6154/88745/6202/51096/6169/55272/6175/6218/5394/6173/6167/116832/23481/51077/6156/117246/6143/6139/23160/26168/11340/3921/10607/11103/6208/6170/22984/10813/60528/9136/6203/6147/8568/27292/6222/1454/56902/51602/6134/6155/9724/6231/6142/23521/54555/10171/5822/6207/10969/6233/6188/54881/1453/4691/23016/200916/6122/6230/2091/55651/55127/8602/6194/6166/3028/10436/9277/84128/6136/6125/4839/6232/134430/6160/92856/65083/6193/10200/6210/6229/6205/11056/9790/140801/6235/55720/6181/7311/6223/25873/55505/51010/26354/56915/51202/9045/51106/57647/6187/6168/6157/6137/79050/22894/6144/9349/55813/4736/22803/51121/6159/25879/6217/81887/6152/57050/51065/6141/6123/55781/6164/54931/6209/11224/6165/6130/6204/1736/6228/10199/6124/25926/83732/27341/6189/6135/6201/6161/54512/10885/6133/9188 161 Human_herpesvirus_2 R-HSA-69002 DNA Replication Pre-Initiation 80/4920 85/10654 1.638706720998185e-21 2.493684140649412e-20 9.562247456625564e-21 5689/5682/143471/5705/5709/5422/1869/4174/5695/84515/4998/5711/10926/5683/990/5699/5702/55388/6117/5001/5558/5696/5691/7314/5718/6118/23594/5700/122706/5707/23198/5557/9861/5698/5692/5713/4175/5710/5719/6233/23649/4999/4172/5000/8318/4173/5706/5714/51053/6119/5688/5687/5427/5708/81620/5704/23595/7311/5694/4176/1017/5684/5720/8317/5690/5717/9491/10197/7316/10213/5426/4171/1871/5715/5701/5685/5686/5716/5693/5721 80 Human_herpesvirus_2 R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 66/4920 67/10654 2.072336501671567e-21 3.086458619510845e-20 1.1835292450755868e-20 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 66 Human_herpesvirus_2 R-HSA-6802952 Signaling by BRAF and RAF fusions 66/4920 67/10654 2.072336501671567e-21 3.086458619510845e-20 1.1835292450755868e-20 4893/71/817/5908/55109/54845/8546/22866/5605/5037/3717/10827/2244/3690/408/5894/8826/1185/4140/3845/3265/818/8805/55750/8844/7094/5594/7414/10533/23164/57085/6714/9061/2335/1445/2266/2243/369/801/57670/805/283455/3674/409/673/816/56829/7450/60/9444/7529/5595/4000/27044/815/22906/8087/5604/10018/10142/54518/80853/10256/5906/808/9715 66 Human_herpesvirus_2 R-HSA-8953897 Cellular responses to external stimuli 329/4920 493/10654 3.950067296545454e-21 5.821151805435406e-20 2.232170993061697e-20 1912/23165/5689/3725/9134/11065/573/4790/5682/7531/1915/7321/51807/817/6045/8697/9530/347688/23677/27327/80012/7295/5925/3091/348995/143471/472/10381/57122/5705/79813/3576/3313/1780/7001/23511/10312/5709/9978/2114/1869/5695/3305/8655/1911/832/23279/4194/1031/5711/5928/1432/1387/4683/10325/7846/23225/5683/3309/23512/57332/5699/7428/5702/192669/9531/8900/51529/4001/29945/8091/8131/2056/51434/2475/3306/1030/6196/9972/10670/23411/8021/4343/6117/10587/6197/29882/3312/4217/3569/64121/55746/5696/5691/7296/7314/51164/996/51182/5718/818/3303/7014/6118/51606/5601/5606/7027/5700/122706/5707/2146/9550/9114/5594/3308/84335/23198/898/10049/10013/27244/3337/10762/7323/1465/890/5970/9261/6667/51433/9861/79902/5598/9883/2932/84733/5698/5692/5713/2877/119504/10376/6195/5710/3301/10540/7157/7324/5719/64682/6233/2353/538/8726/6396/129401/5600/26523/528/405/5608/3297/57521/140735/768/6015/28956/84617/4928/1019/5903/83667/55706/7175/653361/5241/11258/9448/246184/112399/1029/1783/389541/8535/84962/10382/5931/58528/10294/55860/830/7013/7277/1051/1410/50488/5706/10671/8881/527/6774/1639/5714/4927/7867/64223/6119/3552/10370/10524/5688/5687/57805/3310/2908/5708/5602/7266/25824/6009/51143/816/6648/8086/10393/5704/3326/55004/51343/7311/367/25906/2034/57634/10383/84790/55662/648/5694/3304/23466/3456/2113/6416/10641/7280/10728/829/23523/5595/1778/1017/815/25913/81929/5684/5720/9631/3159/7290/10111/7422/5690/57690/5717/1027/9491/545/79023/23636/10197/192670/10808/153129/3490/8550/29855/1781/7316/10213/53371/1026/9532/54205/2289/9588/9688/10121/7415/1871/6647/8994/7322/5715/5701/245972/144577/5685/8649/3320/5686/2033/1021/6767/25842/8453/23135/10963/22824/23112/5609/10542/5716/9529/4520/5599/54583/5052/5693/5721/2288/5034/8480/10919/51382/2950/4193/23043 329 Human_herpesvirus_2 R-HSA-983705 Signaling by the B Cell Receptor (BCR) 99/4920 112/10654 4.8011795314535186e-21 7.001720150036382e-20 2.6848701327207175e-20 5295/8454/5689/5777/4893/4790/5579/5682/84876/143471/5705/5530/5709/5695/4792/5711/5683/2534/5699/5702/30011/2885/3845/3265/3551/5696/5691/7314/6786/5718/8945/4773/5966/80228/5700/122706/5707/5336/23198/8517/10125/5970/25780/9861/5698/5692/5713/5710/5478/5719/6233/7409/801/805/4772/4775/930/5706/6850/8915/5714/5688/5687/4067/5708/695/6654/5704/7311/5293/5694/1147/5684/5720/6885/4690/640/5690/5532/5717/9491/6500/3708/10197/7316/10213/10768/4793/5715/5701/23291/5685/5686/5534/974/5716/808/5693/5721 99 Human_herpesvirus_2 R-HSA-162587 HIV Life Cycle 126/4920 152/10654 4.8737297582666796e-21 7.03424913564263e-20 2.6973436535170987e-20 6884/23165/6875/2237/7852/27243/6874/348995/57122/5431/23511/5435/5433/2960/23279/23327/29082/23225/2965/27183/5439/6873/3836/9972/6881/2967/51616/8021/11198/904/51497/55746/7314/2959/404672/10015/91782/5438/3978/10762/4836/9397/79902/9883/89853/83860/2068/5902/5478/6233/7514/1025/6396/129401/6883/7936/6829/2957/25920/4928/2963/5434/5903/55706/7175/79643/5436/6878/920/4331/4927/8148/2966/2962/54457/8812/128866/905/2071/5901/8086/7311/93343/6880/6908/7251/1104/2547/6882/2961/5432/22916/1234/6877/5905/6917/81929/5440/902/9631/3159/5430/7520/6749/79023/5441/23636/7469/4686/7316/6872/53371/9688/8731/9150/6879/9525/2958/5437/8815/6827/2968/138474/1022/8178/8480 126 Human_herpesvirus_2 R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 78/4920 83/10654 6.92391465487716e-21 9.891306649824514e-20 3.792907061210904e-20 8454/5689/4893/4790/5579/5682/143471/5705/5530/5709/5695/4792/5711/5683/5699/5702/3845/3265/3551/5696/5691/7314/5718/8945/4773/5966/5700/122706/5707/23198/8517/10125/5970/25780/9861/5698/5692/5713/5710/5478/5719/6233/801/805/4772/4775/5706/8915/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/5690/5532/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5534/5716/808/5693/5721 78 Human_herpesvirus_2 R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 86/4920 94/10654 8.39008948545974e-21 1.1864773009741047e-19 4.5496498007277697e-20 114791/10844/440145/7531/11190/203068/54801/51807/347688/79441/10381/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/1454/983/79959/80097/10376/10540/85378/54930/54820/1453/27229/9793/84617/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/9738/1639/55722/4957/5566/7283/22919/10426/22994/1069/5577/10383/5347/84790/80184/22897/5108/7280/10806/1778/115106/4926/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 86 Human_herpesvirus_2 R-HSA-380259 Loss of Nlp from mitotic centrosomes 68/4920 70/10654 8.605913654657276e-21 1.1923646006726224e-19 4.5722251604739654e-20 7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 68 Human_herpesvirus_2 R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 68/4920 70/10654 8.605913654657276e-21 1.1923646006726224e-19 4.5722251604739654e-20 7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 68 Human_herpesvirus_2 R-HSA-5607764 CLEC7A (Dectin-1) signaling 91/4920 101/10654 8.687227804900535e-21 1.1923646006726224e-19 4.5722251604739654e-20 8454/5689/4790/5682/7321/29108/143471/5705/5530/5709/5695/4792/5711/5683/5699/5702/7334/3551/5696/5691/7314/257397/5718/8945/4773/5700/122706/5707/5336/23198/23118/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/801/4791/805/5170/4772/4775/5706/6850/8915/5714/5688/5687/5708/7189/5704/7311/5971/5694/997/1147/5684/5720/6885/5690/3553/5532/5717/9491/6500/3708/10197/7316/10213/10768/7322/5715/5701/23291/5685/5686/5534/5716/808/5693/5721 91 Human_herpesvirus_2 R-HSA-6807505 RNA polymerase II transcribes snRNA genes 71/4920 74/10654 1.2184352609187432e-20 1.6561255973652818e-19 6.35055680192702e-20 6884/51585/5431/5435/23379/5433/2960/55656/5439/10302/904/65123/55197/2959/79871/5438/6667/29101/79664/25896/23248/1025/7702/6829/2957/2963/5434/26173/5436/26512/6878/55756/58490/2962/51808/8812/129685/905/5452/64859/22936/6621/6880/6908/80237/6619/6882/2961/5432/22916/6618/6877/5440/57508/5430/5451/55174/6617/5441/84524/4686/2958/5437/92105/6827/80789/57117/51593/79035/1022/8178 71 Human_herpesvirus_2 R-HSA-2871837 FCERI mediated NF-kB activation 77/4920 82/10654 1.4214213046564487e-20 1.9134517562682963e-19 7.33729620824685e-20 8454/5689/4790/5682/7321/143471/5705/5709/5695/4792/5711/5683/5699/5702/7334/3551/5696/5691/7314/257397/5718/8945/5700/122706/5707/23198/23118/8517/10125/5970/9861/5588/5698/5692/5713/5710/10454/5719/6233/115727/5170/2205/5706/2206/8915/5714/5688/5687/4067/5708/7189/5704/7311/5694/997/1147/5684/5720/6885/5690/5717/9491/6500/10197/7316/10213/7322/5715/5701/23291/5685/5686/5716/10235/5693/5721/2207 77 Human_herpesvirus_2 R-HSA-2408557 Selenocysteine synthesis 85/4920 93/10654 1.6782934036919315e-20 2.2377245382559087e-19 8.580748229402356e-20 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/60678/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 85 Human_herpesvirus_2 R-HSA-909733 Interferon alpha/beta signaling 67/4920 69/10654 1.8240939357671038e-20 2.4091806698810803e-19 9.238211591273315e-20 3443/5777/5770/3107/9021/11274/3662/3106/4599/684/3133/3429/91543/4938/5696/3445/10410/9636/2634/3444/103/3434/3433/3451/3448/3661/3439/10581/3452/4940/3437/6773/7297/5781/3430/3660/3446/3135/3665/10379/3455/4600/8638/3394/3663/6772/8651/3659/25939/3440/3454/3716/3456/3105/3441/51447/54739/2537/3449/8519/3664/6041/1958/4939/6059/3669/3134 67 Human_herpesvirus_2 R-HSA-8878159 Transcriptional regulation by RUNX3 87/4920 96/10654 2.4487076423084132e-20 3.2039165413381107e-19 1.2285695008138619e-19 5689/6046/5682/182/5705/6097/6696/5709/5695/9759/10413/4609/4089/22938/5711/1387/4088/5683/5699/5702/9794/7040/3845/5696/5691/7314/5718/8463/51176/2648/5700/5707/55534/3280/84441/463/865/6714/9861/8850/5698/5692/5713/595/5710/7157/5719/6233/1029/864/5706/10046/5714/6934/5688/5687/5708/5704/7311/5694/4851/3676/57154/5684/5720/2309/1499/10018/5690/5717/9491/10197/64750/7316/10213/1026/5715/5701/5685/5686/2033/861/5716/3516/5693/5721/4193 87 Human_herpesvirus_2 R-HSA-8939902 Regulation of RUNX2 expression and activity 70/4920 73/10654 2.5517325385555623e-20 3.307801438868322e-19 1.2684050630246947e-19 8454/5689/7291/5682/143471/5705/5709/9978/5695/5711/5683/2101/1749/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/865/11059/2099/9861/2932/6502/5698/5692/5713/5710/5719/6233/133522/5706/579/5714/6772/5688/5687/2908/5708/4488/5704/7311/860/1750/5694/57154/5684/5720/10273/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721/10891 70 Human_herpesvirus_2 R-HSA-2990846 SUMOylation 148/4920 188/10654 3.0854378430372776e-20 3.96294768830476e-19 1.5196265571694944e-19 1912/10054/23165/7068/7486/9112/6045/9212/80012/10274/348995/6613/57122/7181/23511/28996/4792/3190/9759/9612/8856/1911/6790/6672/23279/1387/23225/10055/23512/165918/57332/7022/7067/7428/1107/5371/8924/4152/672/115426/9972/10499/6612/5914/8021/6117/11315/55746/7421/10062/79677/7150/6670/3622/1788/51564/51588/3619/7153/51602/2516/8517/332/10762/5465/1655/5970/2099/79902/9656/9883/84733/3066/7157/7158/10155/9063/7155/7690/6396/129401/7703/9189/4791/6015/8554/7020/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/5111/4927/10521/1616/2908/8243/142/1069/8086/7329/367/25942/648/6095/23468/5905/81929/29843/1487/55143/9631/5468/7021/8204/3090/79023/23636/10735/3183/53371/6996/9688/7341/10401/59343/2033/9126/3065/23314/6256/5987/7376/6294/8648/6304/8480/10891/7508/4193 148 Human_herpesvirus_2 R-HSA-2682334 EPH-Ephrin signaling 84/4920 92/10654 3.353482767775181e-20 4.268068977168412e-19 1.636627953651045e-19 71/2042/1947/1212/2051/2045/10094/2050/285220/79784/2047/2534/9475/1948/4628/8976/6093/163/284656/8997/1759/8440/8874/3265/5062/5879/1072/161/10093/5921/2046/6453/4313/2902/2041/102/6714/1943/2043/7525/1942/7410/1213/1211/1175/10109/5663/1173/2904/5747/7074/1949/10627/1945/10451/4318/160/2049/8218/10092/4067/2044/5063/6386/998/2048/10097/387/60/5058/4629/28964/4627/3985/6383/10398/10552/4637/1946/10096/103910/1944/10095/1969 84 Human_herpesvirus_2 R-HSA-68867 Assembly of the pre-replicative complex 66/4920 68/10654 3.8642795449610235e-20 4.8303494312012795e-19 1.8522392555734229e-19 5689/5682/143471/5705/5709/1869/4174/5695/84515/4998/5711/5683/990/5699/5702/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/9861/5698/5692/5713/4175/5710/5719/6233/4999/4172/5000/4173/5706/5714/51053/5688/5687/5708/81620/5704/23595/7311/5694/4176/5684/5720/5690/5717/9491/10197/7316/10213/4171/1871/5715/5701/5685/5686/5716/5693/5721 66 Human_herpesvirus_2 R-HSA-69615 G1/S DNA Damage Checkpoints 66/4920 68/10654 3.8642795449610235e-20 4.8303494312012795e-19 1.8522392555734229e-19 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/993/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/1111/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 66 Human_herpesvirus_2 R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 98/4920 112/10654 4.0715892619721836e-20 5.044446873239874e-19 1.9343367709416051e-19 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/6745/3921/6208/6170/6203/10952/6147/6222/6727/6184/58477/6134/6155/6729/6231/6142/23521/6185/6207/6726/6233/6188/200916/6122/6230/6194/6166/1650/6136/6125/6232/6160/6748/29927/6193/6210/6229/6205/28972/140801/6235/6181/7311/6223/25873/6730/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/9789/6135/6201/6161/6133 98 Human_herpesvirus_2 R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 144/4920 182/10654 4.223345531814403e-20 5.186564688193127e-19 1.98883307592368e-19 1912/23165/7068/7486/9112/6045/9212/80012/10274/348995/6613/57122/7181/23511/28996/4792/3190/9759/9612/8856/1911/6790/6672/23279/1387/23225/23512/165918/57332/7022/7067/7428/1107/5371/8924/4152/672/115426/9972/10499/6612/5914/8021/6117/11315/55746/7421/10062/79677/7150/6670/3622/1788/51564/51588/3619/7153/51602/2516/8517/332/10762/5465/1655/5970/2099/79902/9656/9883/84733/3066/7157/7158/10155/9063/7155/7690/6396/129401/7703/9189/4791/6015/8554/7020/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/5111/4927/10521/1616/2908/8243/142/1069/8086/7329/367/25942/648/6095/23468/5905/81929/1487/55143/9631/5468/7021/8204/3090/79023/23636/10735/3183/53371/6996/9688/7341/10401/2033/9126/3065/23314/6256/5987/7376/6294/8648/6304/8480/10891/7508/4193 144 Human_herpesvirus_2 R-HSA-1226099 Signaling by FGFR in disease 62/4920 63/10654 4.408419984149912e-20 5.320506877422308e-19 2.0401943665303586e-19 5295/4893/11052/2250/5335/9530/613/5431/6776/5435/5433/11064/5439/2264/2885/9846/2252/2253/3845/3265/7750/8805/26127/5290/8823/8074/2260/5438/2249/2248/399687/2247/2246/2251/6777/1523/2963/5434/5436/9208/6774/2263/6772/2962/6654/11160/2549/5432/22916/8822/5440/5430/8817/5441/2254/4686/26281/10818/2261/5437/2255/27006 62 Human_herpesvirus_2 R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 62/4920 63/10654 4.408419984149912e-20 5.320506877422308e-19 2.0401943665303586e-19 5689/11065/5682/7321/8697/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/5707/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 62 Human_herpesvirus_2 R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 78/4920 84/10654 5.3126953695777744e-20 6.357071382400756e-19 2.4376739887401397e-19 7124/1052/84498/4790/79718/9441/892/5469/9612/1387/84246/4023/55588/10499/23054/7040/85441/9282/23097/51129/7471/3952/5465/10025/5970/6604/9439/896/9370/1879/9412/9969/54797/5105/55090/1019/9440/6721/9862/1051/9442/1050/1024/9314/9968/5346/10001/23389/9443/9477/2167/51586/400569/6517/80306/8841/5468/29079/90390/6720/6837/688/9611/81857/2033/9967/7026/6256/51003/10498/948/112950/27332/8202/8648/1959/10891/219541 78 Human_herpesvirus_2 R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 75/4920 80/10654 5.974708402014901e-20 7.088637087136324e-19 2.7181991837891166e-19 23165/201626/5335/348995/317649/57122/11274/23511/4734/23279/8672/23225/1973/3836/4599/9972/8021/7334/4938/55746/7314/402569/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/1977/51191/6233/5610/4940/6396/129401/4928/3838/5903/55706/7175/2316/4600/8638/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/1974/5595/3837/81929/9631/79023/23636/7316/53371/9688/6041/4939/6059/5300/9775/5495/8480 75 Human_herpesvirus_2 R-HSA-162599 Late Phase of HIV Life Cycle 116/4920 139/10654 6.106314935418317e-20 7.18389992402155e-19 2.754728542293977e-19 6884/23165/6875/27243/6874/348995/57122/5431/23511/5435/5433/2960/23279/23327/29082/23225/2965/27183/5439/6873/9972/6881/2967/51616/8021/11198/904/51497/55746/7314/2959/404672/10015/91782/5438/10762/4836/9397/79902/9883/89853/83860/2068/5902/5478/6233/7514/1025/6396/129401/6883/7936/6829/2957/25920/4928/2963/5434/5903/55706/7175/79643/5436/6878/4331/4927/8148/2966/2962/54457/8812/128866/905/2071/5901/8086/7311/93343/6880/6908/7251/1104/6882/2961/5432/22916/6877/5905/6917/81929/5440/902/9631/5430/6749/79023/5441/23636/7469/4686/7316/6872/53371/9688/8731/9150/6879/9525/2958/5437/6827/2968/138474/1022/8178/8480 116 Human_herpesvirus_2 R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 71/4920 75/10654 1.2525627910820806e-19 1.4613232562624273e-18 5.603570381156676e-19 23165/8683/6431/84271/199746/348995/57122/23511/65109/23279/23225/9877/9972/8021/55746/7919/6432/8563/6430/56001/80145/10762/22794/9785/11338/29107/4116/79902/9883/51213/10250/26097/51362/57187/6396/129401/79228/2733/84324/4928/5903/55706/7175/6428/10212/55110/84321/6429/4927/10569/9295/10482/8086/9939/6426/22916/10921/81929/9631/79023/23636/4686/53371/7307/9688/9984/10189/9775/84248/6427/8480 71 Human_herpesvirus_2 R-HSA-3858494 Beta-catenin independent WNT signaling 120/4920 146/10654 1.7252318109746824e-19 1.970725173324578e-18 7.556916078161915e-19 2788/5689/5579/5682/5331/5578/1212/27327/143471/5705/5530/5709/5695/5881/5711/5683/5699/2782/5702/192669/57216/1855/163/4343/3845/5696/5691/4920/7314/5879/2787/5718/51176/161/51701/5700/122706/5707/1856/8322/23198/10681/7471/2792/9861/5698/5692/5713/2785/2783/2784/5710/5719/6233/7474/1857/1213/1211/7855/1175/26523/801/2791/805/1173/144165/4772/409/5706/160/5714/6934/5688/5687/4919/23236/5708/2786/5704/7311/387/5694/57154/27161/815/5684/5720/54331/6885/1499/59345/5690/5532/57690/5717/9491/51764/94235/3708/10197/192670/64750/7316/10213/55970/5216/5715/5701/2793/5685/5686/5534/23112/23513/5716/808/5693/5721/6259/2790 120 Human_herpesvirus_2 R-HSA-69563 p53-Dependent G1 DNA Damage Response 64/4920 66/10654 1.7314228308494505e-19 1.970725173324578e-18 7.556916078161915e-19 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Human_herpesvirus_2 R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 64/4920 66/10654 1.7314228308494505e-19 1.970725173324578e-18 7.556916078161915e-19 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Human_herpesvirus_2 R-HSA-5663220 RHO GTPases Activate Formins 116/4920 140/10654 1.9512443466938684e-19 2.2030178107833998e-18 8.447662281951382e-19 55839/11130/71/6249/9735/5526/51807/9212/347688/388/147841/348995/10381/57122/1780/23122/3688/5048/57405/8655/23279/2491/7846/1060/11004/1855/9184/5518/23332/25909/10726/81930/55746/5879/5515/79682/10403/25936/1856/389/3619/64105/332/5528/6714/79902/3796/5519/81565/91687/10376/83540/1857/7514/54820/1729/6396/64946/9793/140735/220134/84617/4928/5903/55055/80776/1783/401541/10382/79172/7277/79980/6232/5501/54821/9183/1062/699/752/22919/5529/51143/998/10383/5347/387/60/84790/84643/7280/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/5216/55166/79003/5527/701/23380/57551 116 Human_herpesvirus_2 R-HSA-9013694 Signaling by NOTCH4 76/4920 82/10654 2.184057786935046e-19 2.4461447213672513e-18 9.37995344283683e-19 8454/5689/5682/182/5705/5709/9978/5695/22938/5711/1387/4088/5683/5699/4853/5702/9794/388585/5696/5691/7314/5718/2648/5700/5707/55534/3280/84441/7534/102/9861/8850/5698/5692/5713/5710/5719/6233/2324/5663/5706/10460/10046/5714/5688/5687/5708/59/4855/5704/23493/7311/5694/4851/5684/5720/23462/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/2033/55294/5716/54567/3516/5693/5721 76 Human_herpesvirus_2 R-HSA-5687128 MAPK6/MAPK4 signaling 81/4920 89/10654 2.6573289075902504e-19 2.952587675100278e-18 1.1321952739106331e-18 2308/5689/2118/3725/5682/27327/143471/5705/5709/5695/4609/5711/5683/5699/5702/192669/8997/4343/5062/5696/5691/7314/5879/5718/5700/122706/5707/5567/23198/3337/983/9861/5698/5692/5713/5710/8555/896/5719/6233/7514/26523/5568/3315/5706/5597/5714/5566/5688/5687/5708/5063/998/5704/7311/5694/5058/27161/5684/5720/2309/10642/5690/57690/5717/9491/10197/192670/8550/7316/10213/5715/5701/5685/5686/8556/23112/5716/8202/5693/5721 81 Human_herpesvirus_2 R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 59/4920 60/10654 4.350443886525252e-19 4.721411969872366e-18 1.8104662440863955e-18 8454/5689/9134/5682/5705/5709/5753/5695/5711/5683/5699/5702/8900/5696/5691/7314/5718/5700/5707/898/890/9861/6502/5698/5692/5713/595/5710/5719/6233/1163/1019/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/5690/5717/1027/9491/6500/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721 59 Human_herpesvirus_2 R-HSA-5610780 Degradation of GLI1 by the proteasome 59/4920 60/10654 4.350443886525252e-19 4.721411969872366e-18 1.8104662440863955e-18 8454/5689/5682/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/83737/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/8650/9861/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/2735/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Human_herpesvirus_2 R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 59/4920 60/10654 4.350443886525252e-19 4.721411969872366e-18 1.8104662440863955e-18 8454/5689/5682/1452/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/2737/9861/2932/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Human_herpesvirus_2 R-HSA-9009391 Extra-nuclear estrogen signaling 72/4920 77/10654 5.113368291368055e-19 5.506704313780983e-18 2.1115933834799257e-18 5295/2788/374/4893/857/2770/7039/2782/3845/3265/8877/2773/2787/1839/5290/4316/5594/2069/10681/4313/2792/6714/2099/10000/2785/595/2783/2784/2771/7514/2353/255324/801/2791/805/5170/5590/6464/5747/1903/3315/4318/8503/2786/208/1956/858/3480/5595/596/685/54331/2309/59345/207/1027/51764/94235/2100/1950/55970/4314/346562/2793/3320/4846/2002/1385/5296/808/3276/2790 72 Human_herpesvirus_2 R-HSA-674695 RNA Polymerase II Pre-transcription Events 77/4920 84/10654 7.088800182250656e-19 7.575816988664823e-18 2.905012529488015e-18 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/11198/904/51497/4300/80349/2959/404672/5438/83860/2068/1025/23168/55677/6883/7936/6829/2957/123169/25920/85403/2963/5434/5436/9646/6878/79577/4331/8148/2966/2962/4298/54457/8812/905/2071/27125/6880/6908/6882/2961/5432/22916/55840/6877/6917/5440/902/6830/5430/6749/5441/7469/4686/6872/9150/6879/54623/2958/5437/6827/2968/138474/1022/8178 77 Human_herpesvirus_2 R-HSA-166520 Signaling by NTRKs 89/4920 101/10654 7.7421638362752e-19 8.211385886958545e-18 3.1487269190592916e-18 5295/627/9252/4893/5335/5291/1848/1785/5605/5898/1432/2534/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5879/5515/5607/161/5290/3667/5899/1849/5594/5528/9261/6714/5519/5598/4208/4909/4914/6195/1213/1211/5600/1175/6300/5781/1846/25920/4908/1173/6464/2904/7074/160/673/6774/26052/7867/2889/6654/5900/387/2549/1020/4916/7529/5595/25759/5516/1845/4915/5604/10817/4205/57498/10818/466/53358/4803/2002/1398/1385/5906/8851/5296/581 89 Human_herpesvirus_2 R-HSA-187037 Signaling by NTRK1 (TRKA) 74/4920 80/10654 8.941467673904718e-19 9.412071235689177e-18 3.6091400978958496e-18 5295/9252/4893/5335/5291/1848/1785/5605/5898/1432/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5515/5607/161/5290/3667/5899/1849/5594/5528/9261/6714/5519/5598/4208/4914/6195/1213/1211/5600/1175/6300/1846/1173/6464/160/673/6774/26052/7867/2889/6654/5900/387/7529/5595/25759/5516/1845/4915/5604/4205/57498/10818/466/53358/4803/2002/1398/1385/5906/5296 74 Human_herpesvirus_2 R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 58/4920 59/10654 9.324469813331876e-19 9.741983387063154e-18 3.735647764964066e-18 5689/5682/143471/5705/5709/5695/84515/4998/5711/5683/990/5699/5702/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/4999/5000/5706/5714/51053/5688/5687/5708/81620/5704/23595/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 58 Human_herpesvirus_2 R-HSA-202403 TCR signaling 101/4920 119/10654 1.3433435435249203e-18 1.3930970080999172e-17 5.341950933315471e-18 5295/8454/5689/5335/4790/5682/5291/7321/143471/5705/5788/5709/5695/4792/3113/5711/5683/55824/5699/5702/26191/3127/7334/3551/5062/5696/5691/7314/5718/8945/5290/5700/122706/5707/23198/23118/8517/5970/9861/5588/5698/5692/5713/1445/5710/916/5719/6233/3702/3932/5170/3937/3123/5706/3122/920/8915/5714/5795/5688/5687/5708/5063/7189/7535/5704/7311/5694/5058/997/1147/55740/9402/5684/5720/6885/4690/5690/5717/9491/6500/10197/919/7316/10213/7322/5715/5701/27040/23291/915/5685/917/5686/7408/5728/7454/5716/5296/5693/5721 101 Human_herpesvirus_2 R-HSA-1236974 ER-Phagosome pathway 76/4920 83/10654 1.4195612012376008e-18 1.461313001274001e-17 5.603531057516846e-18 8773/5689/5682/3107/811/143471/5705/5709/5695/567/3106/5711/5683/5699/5702/3133/3551/5696/5691/7314/5718/10952/5700/122706/5707/23198/6892/8517/6810/9861/5698/5692/5713/5710/5719/6233/3135/6890/5706/9554/29927/5714/5688/5687/5708/2923/695/5704/7311/5694/8673/3105/1147/5684/5720/5690/5717/9491/10197/7099/4615/6891/7316/10213/5715/5701/9341/5685/5686/114609/948/5716/3134/7097/5693/5721 76 Human_herpesvirus_2 R-HSA-9020702 Interleukin-1 signaling 90/4920 103/10654 1.7413355083062332e-18 1.779466942794691e-17 6.823519855829265e-18 8454/5689/4790/5682/8878/143471/5705/5709/9978/5695/4792/177/5711/5683/5699/5702/3654/7334/3551/5696/5691/7314/257397/5718/8945/5700/122706/5707/23198/23118/8517/5970/9861/5698/5692/5713/5710/10454/5719/6233/7850/5608/4791/3557/351/54472/5706/79155/5714/3552/5688/5687/5708/57162/7189/5704/7311/5694/6416/3554/3556/1147/5684/5720/6885/5604/4215/5690/3553/5717/9491/6500/246330/10197/4615/7316/10213/4793/3146/5715/5701/23291/5685/5686/6288/6285/5716/57161/5693/5721 90 Human_herpesvirus_2 R-HSA-72187 mRNA 3'-end processing 57/4920 58/10654 1.9977685455074595e-18 2.0267217128336547e-17 7.771639650715518e-18 8683/6431/84271/51585/199746/81608/1477/65109/9877/53981/7919/6432/8563/6430/11051/80145/8106/22794/9785/11338/4116/1478/51213/10250/26097/51362/23283/10914/57187/79228/84324/6428/10212/55110/84321/6429/10898/10569/9295/51692/9939/6426/22916/1479/10921/79869/29894/4686/8189/10978/7307/9984/10189/9775/84248/6427/55339 57 Human_herpesvirus_2 R-HSA-73856 RNA Polymerase II Transcription Termination 64/4920 67/10654 2.1213661810538824e-18 2.1366278082557087e-17 8.19308407677001e-18 8683/6431/84271/51585/199746/81608/1477/65109/9877/53981/7919/6432/8563/6430/134353/11051/80145/8106/22794/9785/11338/4116/1478/51213/10250/26097/51362/23283/6636/10914/57187/79228/84324/6635/7884/6428/10212/6637/55110/84321/6429/10898/10569/9295/51692/9939/6426/22916/1479/10921/79869/29894/4686/8189/10978/7307/9984/10189/6634/9775/84248/6427/55339/6628 64 Human_herpesvirus_2 R-HSA-5696398 Nucleotide Excision Repair 95/4920 111/10654 4.3507509164073134e-18 4.3507509164073134e-17 1.6683330581712255e-17 2074/10445/5982/6613/5431/5435/9978/5433/85015/10980/2965/5439/10987/2067/2967/6612/6117/7334/10714/91603/7314/6118/404672/86/5438/3978/1643/5985/10920/2068/5984/6233/93973/8607/7874/5424/5886/8451/8554/10450/5434/5436/7515/8450/4331/5425/5111/2966/6119/5427/1161/1642/142/125476/2071/1069/7329/51426/2873/7311/3980/60/8533/5983/5432/51138/7528/9318/6917/5440/902/27339/5430/57804/5441/7336/2072/7316/64708/5426/283899/7341/5437/10401/54617/2033/2968/56949/5887/9716/5981/57461/1022/8178/7508 95 Human_herpesvirus_2 R-HSA-8943724 Regulation of PTEN gene transcription 59/4920 61/10654 7.283368172719058e-18 7.231713079295518e-17 2.7730629101058e-17 1912/3725/6591/1822/9112/6045/80012/1911/5928/10325/23512/57332/1107/2475/1386/10670/64121/23186/2146/51564/5594/84232/7101/84733/57459/3066/7157/8726/57521/6015/28956/389541/9219/8535/5931/58528/1108/2122/64223/10014/54815/6009/55004/57504/648/23466/53615/5595/8841/5468/5978/153129/57167/1958/8649/6615/3065/23028/10542 59 Human_herpesvirus_2 R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 55/4920 56/10654 9.159289425457885e-18 9.030285349042984e-17 3.462740998505204e-17 5689/5682/26986/143471/5705/5709/5695/5711/5683/5699/5702/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/9861/5698/5692/5713/1981/5710/5719/6233/3315/5706/5714/5688/5687/5708/5704/7311/5694/3304/5684/5720/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 55 Human_herpesvirus_2 R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 58/4920 60/10654 1.535712216907252e-17 1.4930535442153836e-16 5.725242913908614e-17 8454/5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/5970/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 58 Human_herpesvirus_2 R-HSA-5610783 Degradation of GLI2 by the proteasome 58/4920 60/10654 1.535712216907252e-17 1.4930535442153836e-16 5.725242913908614e-17 8454/5689/5682/1452/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/9861/2932/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 58 Human_herpesvirus_2 R-HSA-1169408 ISG15 antiviral mechanism 67/4920 72/10654 1.794932503907848e-17 1.7211681544321828e-16 6.599968110980551e-17 23165/5335/348995/317649/57122/11274/23511/4734/23279/8672/23225/1973/3836/4599/9972/8021/7334/55746/7314/402569/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/1977/51191/6233/5610/6396/129401/4928/3838/5903/55706/7175/4600/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/1974/5595/3837/81929/9631/79023/23636/7316/53371/9688/5300/9775/5495/8480 67 Human_herpesvirus_2 R-HSA-199992 trans-Golgi Network Vesicle Budding 67/4920 72/10654 1.794932503907848e-17 1.7211681544321828e-16 6.599968110980551e-17 27131/8773/8906/162/1176/27243/5286/1212/1174/1785/8546/11154/7037/3482/408/6456/7164/3312/1362/26258/25977/10618/6643/10053/6810/55330/8301/9146/8729/4074/2495/388552/152503/6844/54885/1213/2580/1211/23431/8907/351/84062/9685/9179/9026/8775/9829/8905/51429/8673/23557/2512/164/1777/130340/6272/2799/2804/7163/286451/9698/5878/81567/10717/6845/375/4952 67 Human_herpesvirus_2 R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 54/4920 55/10654 1.9599654800745865e-17 1.8540214000705547e-16 7.1094053686916e-17 8454/5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/26271/5706/5714/5688/5687/5708/5704/51343/7311/5694/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 54 Human_herpesvirus_2 R-HSA-8941858 Regulation of RUNX3 expression and activity 54/4920 55/10654 1.9599654800745865e-17 1.8540214000705547e-16 7.1094053686916e-17 5689/5682/5705/5709/5695/5711/5683/5699/5702/7040/5696/5691/7314/5718/5700/5707/865/6714/9861/5698/5692/5713/5710/5719/6233/1029/864/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/2033/5716/5693/5721/4193 54 Human_herpesvirus_2 R-HSA-3371556 Cellular response to heat stress 79/4920 89/10654 2.7452746852130823e-17 2.5794527243612854e-16 9.89113450694929e-17 23165/573/7531/1915/817/9530/348995/472/57122/3313/23511/3305/23279/1387/23225/3309/9531/2475/3306/9972/23411/8021/6117/3312/55746/51182/818/3303/6118/5594/3308/84335/10049/10013/3337/10762/9261/79902/9883/2932/6396/129401/3297/57521/4928/5903/55706/7175/1410/4927/64223/6119/57805/3310/7266/816/8086/3326/3304/10728/5595/815/81929/9631/545/79023/23636/10808/53371/9532/9688/7415/3320/2033/6767/22824/9529/2288/8480 79 Human_herpesvirus_2 R-HSA-446652 Interleukin-1 family signaling 113/4920 140/10654 2.92756695055104e-17 2.732395820514304e-16 1.0477608033551091e-16 8454/834/5689/5777/4790/5682/1511/26469/5783/27178/8878/143471/5705/5709/9978/5695/4792/59307/3606/177/5711/4088/5683/5699/5702/3654/7334/3551/5696/5691/7314/3596/257397/5718/8945/90865/5700/122706/5707/29110/23198/23118/8517/3565/5970/8809/9861/5698/5692/5713/5710/10454/5719/6233/7850/5781/5608/4791/3557/351/5782/54472/5706/79155/6774/5780/5714/3552/5688/5687/5708/57162/5771/7189/5704/7311/5694/6416/3554/3556/1147/5778/5684/5720/6885/5604/4215/5690/3553/5717/9491/6500/25930/246330/10197/4615/7316/10213/4793/3146/5715/5701/23291/5685/5686/6288/6285/5716/5599/5784/57161/5693/5721 113 Human_herpesvirus_2 R-HSA-5676590 NIK-->noncanonical NF-kB signaling 57/4920 59/10654 3.235943312447488e-17 2.9804741035700547e-16 1.1428885660306223e-16 8454/5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 57 Human_herpesvirus_2 R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 57/4920 59/10654 3.235943312447488e-17 2.9804741035700547e-16 1.1428885660306223e-16 6227/6206/1965/6234/27335/6191/8668/6224/8662/26986/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1978/1968/6230/8669/6194/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 57 Human_herpesvirus_2 R-HSA-1169091 Activation of NF-kappaB in B cells 63/4920 67/10654 4.0626264661104056e-17 3.717435982061809e-16 1.4254829705650546e-16 8454/5689/4790/5579/5682/143471/5705/5709/5695/4792/5711/5683/5699/5702/3551/5696/5691/7314/5718/8945/5966/5700/122706/5707/23198/8517/5970/9861/5698/5692/5713/5710/5719/6233/5706/8915/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/5690/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5716/5693/5721 63 Human_herpesvirus_2 R-HSA-9604323 Negative regulation of NOTCH4 signaling 53/4920 54/10654 4.1922539389289856e-17 3.8111399444808965e-16 1.4614145651768851e-16 8454/5689/5682/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/5707/7534/9861/5698/5692/5713/5710/5719/6233/5706/10460/5714/5688/5687/5708/4855/5704/7311/5694/5684/5720/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721 53 Human_herpesvirus_2 R-HSA-5621481 C-type lectin receptors (CLRs) 114/4920 142/10654 4.589139028920952e-17 4.1450288003156987e-16 1.5894471339556434e-16 8454/5689/4586/9252/4893/4790/5682/7321/29108/143471/5705/5530/5709/5695/4792/5711/1387/5683/2534/5699/5702/5894/3845/7334/3265/3551/5062/5696/5691/7314/257397/5718/8945/4773/4589/5700/122706/5707/5567/5336/4582/23198/23118/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/801/4791/805/5170/4772/5568/4775/5706/6850/8915/5714/5566/5688/5687/4067/5708/5063/7189/5704/30835/7311/5971/4585/5694/5058/997/1147/5684/5720/6885/5690/3553/5532/5717/9491/6500/3708/10197/7316/10213/94025/10768/7322/5715/5701/23291/5685/5686/2033/5534/200958/5716/808/5693/5721/2207 114 Human_herpesvirus_2 R-HSA-199418 Negative regulation of the PI3K/AKT network 93/4920 110/10654 5.403062809292015e-17 4.848902521159501e-16 1.859353598339357e-16 5295/374/3643/2250/5291/5526/7039/3082/941/2064/145957/2534/9965/2264/3630/3654/9542/2885/8660/5518/2252/2253/5879/5515/1839/5290/3667/8823/90865/2065/3815/5594/2069/8074/57761/2260/5528/2249/6714/2099/2248/5519/2247/10000/7409/2246/2251/5154/3932/8394/255324/5781/23239/930/2263/4233/8503/5159/3084/5529/7189/208/10718/5293/1956/2549/5595/3556/5516/8822/685/5305/5525/207/8817/4615/2100/2254/152831/1950/26281/10818/2261/2255/5728/2066/27006/942/5527/5155/4254/5296/5156 93 Human_herpesvirus_2 R-HSA-72649 Translation initiation complex formation 56/4920 58/10654 6.813925659623482e-17 6.037655647767642e-16 2.3151912634296975e-16 6227/6206/1965/6234/27335/6191/8668/6224/8662/26986/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1968/6230/8669/6194/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 56 Human_herpesvirus_2 R-HSA-72702 Ribosomal scanning and start codon recognition 56/4920 58/10654 6.813925659623482e-17 6.037655647767642e-16 2.3151912634296975e-16 6227/6206/1965/6234/27335/6191/8668/6224/8662/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1968/6230/8669/6194/1983/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 56 Human_herpesvirus_2 R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 70/4920 77/10654 8.922044277406823e-17 7.855888042999719e-16 3.012408196939741e-16 5689/5682/51807/63943/347688/143471/10381/5705/5709/5695/5711/7846/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/983/9861/5698/5692/5713/10376/5710/7157/5719/6233/84617/51512/10382/7277/5706/9133/891/5714/5688/5687/5708/22919/5704/3326/7311/10383/5347/84790/5694/7280/5684/5720/5690/5717/9491/10197/7316/10213/1026/5715/5701/5685/3320/5686/5716/5693/5721 70 Human_herpesvirus_2 R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 88/4920 103/10654 9.543127738261052e-17 8.35023677097842e-16 3.201970491127063e-16 5295/374/3643/2250/5291/5526/7039/3082/941/2064/145957/2534/9965/2264/3630/3654/9542/2885/8660/5518/2252/2253/5879/5515/1839/5290/3667/8823/90865/2065/3815/5594/2069/8074/2260/5528/2249/6714/2099/2248/5519/2247/7409/2246/2251/5154/3932/8394/255324/5781/930/2263/4233/8503/5159/3084/5529/7189/10718/5293/1956/2549/5595/3556/5516/8822/685/5305/5525/207/8817/4615/2100/2254/152831/1950/26281/10818/2261/2255/2066/27006/942/5527/5155/4254/5296/5156 88 Human_herpesvirus_2 R-HSA-190236 Signaling by FGFR 77/4920 87/10654 1.031473375424405e-16 8.969333699342652e-16 3.43936856140207e-16 5295/4893/2250/5335/54845/5431/5435/5433/8569/9965/5439/2264/2885/5518/2252/2253/3845/3265/7314/5515/5290/8823/23768/5594/8074/2260/5438/3185/2249/6714/2248/4670/2247/6233/2246/2251/200734/5781/5725/2963/5434/6464/5436/673/2263/2962/23767/80004/6654/7311/53834/2549/5432/22916/5595/5516/8822/10253/5440/5430/3178/8817/10817/5441/2254/4686/7316/152831/26281/10818/2261/867/5437/2255/27006/3187/161742 77 Human_herpesvirus_2 R-HSA-5654738 Signaling by FGFR2 67/4920 73/10654 1.1979709701762425e-16 1.035283554473296e-15 3.969884306626924e-16 5295/4893/2250/5335/54845/5431/5435/5433/8569/5439/2885/5518/2252/2253/3845/3265/7314/5515/5290/8823/5594/8074/5438/3185/2249/6714/2248/4670/2247/6233/2246/2251/5781/5725/2963/5434/6464/5436/673/2263/2962/80004/6654/7311/2549/5432/22916/5595/5516/8822/10253/5440/5430/3178/8817/10817/5441/2254/4686/7316/26281/10818/867/5437/2255/27006/3187 67 Human_herpesvirus_2 R-HSA-4641258 Degradation of DVL 55/4920 57/10654 1.4338073702427333e-16 1.2043691692088343e-15 4.618257716515078e-16 5689/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/1855/5696/5691/7314/5718/5700/122706/5707/1856/23198/9861/5698/5692/5713/5710/5719/6233/1857/5706/5714/5688/5687/5708/51339/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/23072/5693/5721 55 Human_herpesvirus_2 R-HSA-69541 Stabilization of p53 55/4920 57/10654 1.4338073702427333e-16 1.2043691692088343e-15 4.618257716515078e-16 5689/5682/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/51230/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721/4193 55 Human_herpesvirus_2 R-HSA-8948751 Regulation of PTEN stability and activity 64/4920 69/10654 1.498250240273029e-16 1.2043691692088343e-15 4.618257716515078e-16 5689/5682/1459/1460/143471/5705/5709/5695/1457/4734/11060/5711/5683/5699/2444/5702/8975/5696/5691/7314/5718/5700/122706/5707/23198/9861/81847/5698/10000/5692/5713/5710/5719/6233/331/23608/5706/5714/5688/5687/5708/208/5704/7311/5694/5684/5720/10273/207/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5728/5987/5716/5693/5721 64 Human_herpesvirus_2 R-HSA-167161 HIV Transcription Initiation 47/4920 47/10654 1.5054614615110428e-16 1.2043691692088343e-15 4.618257716515078e-16 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_herpesvirus_2 R-HSA-167162 RNA Polymerase II HIV Promoter Escape 47/4920 47/10654 1.5054614615110428e-16 1.2043691692088343e-15 4.618257716515078e-16 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_herpesvirus_2 R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 47/4920 47/10654 1.5054614615110428e-16 1.2043691692088343e-15 4.618257716515078e-16 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Human_herpesvirus_2 R-HSA-6802949 Signaling by RAS mutants 47/4920 47/10654 1.5054614615110428e-16 1.2043691692088343e-15 4.618257716515078e-16 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Human_herpesvirus_2 R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 47/4920 47/10654 1.5054614615110428e-16 1.2043691692088343e-15 4.618257716515078e-16 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Human_herpesvirus_2 R-HSA-73776 RNA Polymerase II Promoter Escape 47/4920 47/10654 1.5054614615110428e-16 1.2043691692088343e-15 4.618257716515078e-16 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_herpesvirus_2 R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 47/4920 47/10654 1.5054614615110428e-16 1.2043691692088343e-15 4.618257716515078e-16 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_herpesvirus_2 R-HSA-75953 RNA Polymerase II Transcription Initiation 47/4920 47/10654 1.5054614615110428e-16 1.2043691692088343e-15 4.618257716515078e-16 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_herpesvirus_2 R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 47/4920 47/10654 1.5054614615110428e-16 1.2043691692088343e-15 4.618257716515078e-16 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_herpesvirus_2 R-HSA-9649948 Signaling downstream of RAS mutants 47/4920 47/10654 1.5054614615110428e-16 1.2043691692088343e-15 4.618257716515078e-16 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Human_herpesvirus_2 R-HSA-180534 Vpu mediated degradation of CD4 51/4920 52/10654 1.915414351896411e-16 1.481535962792804e-15 5.681077752062631e-16 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/920/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_herpesvirus_2 R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 51/4920 52/10654 1.915414351896411e-16 1.481535962792804e-15 5.681077752062631e-16 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_herpesvirus_2 R-HSA-69610 p53-Independent DNA Damage Response 51/4920 52/10654 1.915414351896411e-16 1.481535962792804e-15 5.681077752062631e-16 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_herpesvirus_2 R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 51/4920 52/10654 1.915414351896411e-16 1.481535962792804e-15 5.681077752062631e-16 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_herpesvirus_2 R-HSA-72165 mRNA Splicing - Minor Pathway 51/4920 52/10654 1.915414351896411e-16 1.481535962792804e-15 5.681077752062631e-16 6633/6431/4904/51639/23450/5431/5435/5433/9416/8233/23020/5439/9410/10907/10262/6432/83443/10081/5438/9343/6636/2963/6635/5434/6632/24148/154007/5436/6637/55954/57819/2962/6426/5432/22916/23451/5440/55599/5430/85437/11325/5441/79622/10594/4686/5437/11066/6634/6427/10992/6628 51 Human_herpesvirus_2 R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 51/4920 52/10654 1.915414351896411e-16 1.481535962792804e-15 5.681077752062631e-16 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/2932/5698/5692/5713/595/5710/5719/6233/1019/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_herpesvirus_2 R-HSA-5688426 Deubiquitination 206/4920 297/10654 2.375593370594372e-16 1.8273795158418244e-15 7.007244759994966e-16 5689/221937/645836/5682/79594/7419/10474/7321/4738/7375/9817/10445/91833/6478/3091/143471/100287513/5705/11274/55031/8239/5709/5695/4792/9986/11047/4609/392188/4194/4089/100287144/5711/4088/114803/5683/324/408/55777/64135/5699/8724/8312/100287327/5702/8900/8975/57599/377630/672/6881/51616/7040/728386/7345/3054/1540/100287404/5696/5691/7314/5718/3607/90865/2648/5700/122706/5707/8027/8737/171023/55611/100287364/51720/57646/23198/63967/9101/8517/86/993/890/7417/80124/983/4092/2099/1643/9861/23586/81847/64426/100287441/8850/7128/6502/5698/9146/5692/5713/5710/10454/8473/7157/10869/9958/5719/6233/100287478/9804/55593/93973/10318/23770/8607/7874/100287178/5886/100287238/10600/114785/23326/51651/8237/4303/409/330/5706/4287/27005/7706/580/7416/79155/25862/9738/84132/5714/79589/5688/9097/5687/5708/125476/4087/63891/84749/7189/5704/7048/7311/367/114548/387/60/5694/7528/9960/23358/23032/5684/8295/5720/10617/7186/56957/6885/991/5690/2625/57506/5717/9491/4086/1080/10197/64750/7316/10213/8314/55252/8678/9100/7415/5715/283899/3416/5701/329/9099/5685/54617/5686/2033/221656/5728/5716/79184/78990/5887/9736/5693/154/10254/5721/100287205/4193 206 Human_herpesvirus_2 R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 71/4920 79/10654 2.4310427007099493e-16 1.8598140879748246e-15 7.131617931332034e-16 2074/5982/5431/5435/9978/5433/10980/2965/5439/10987/2067/2967/6117/10714/91603/7314/6118/404672/5438/3978/5985/10920/2068/5984/6233/7874/5424/8451/10450/5434/5436/7515/8450/4331/5425/5111/2966/6119/5427/1161/1642/2071/51426/2873/7311/3980/8533/5983/5432/51138/9318/6917/5440/902/27339/5430/57804/5441/2072/7316/64708/5426/5437/2033/2968/56949/9716/5981/57461/1022/8178 71 Human_herpesvirus_2 R-HSA-432722 Golgi Associated Vesicle Biogenesis 54/4920 56/10654 3.0148951993351414e-16 2.2939419994941295e-15 8.796318945428616e-16 27131/162/1176/5286/1174/1785/8546/7037/3482/408/6456/7164/3312/1362/26258/25977/10618/6643/10053/55330/8301/2495/388552/152503/6844/54885/1213/2580/1211/23431/8907/84062/9685/9026/8775/9829/8905/51429/8673/23557/2512/164/130340/6272/2804/7163/286451/9698/5878/81567/10717/6845/375/4952 54 Human_herpesvirus_2 R-HSA-195253 Degradation of beta-catenin by the destruction complex 73/4920 82/10654 3.139404878212131e-16 2.3757658537821533e-15 9.110079589690964e-16 8454/5689/5682/5526/1452/143471/5705/5709/9978/5695/5711/5683/324/5699/8312/5702/5518/5696/5691/7314/5515/5718/51176/8945/5700/122706/5707/23198/5528/7091/9861/5519/2932/5698/5692/5713/5710/5719/6233/10023/5706/5714/6934/5688/5687/5708/5529/5704/7311/5694/5516/5684/5720/1487/1499/5525/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/3065/5527/1488/5716/5693/5721 73 Human_herpesvirus_2 R-HSA-1234174 Cellular response to hypoxia 68/4920 75/10654 3.5102034918360954e-16 2.642088649769104e-15 1.0131317378813857e-15 5689/5682/7321/3091/143471/5705/5709/9978/5695/5711/1387/5683/5699/7428/5702/2056/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/405/768/112399/84962/5706/5714/10370/5688/5687/5708/5704/7311/2034/55662/5694/5684/5720/7422/5690/5717/9491/10197/7316/10213/8994/7322/5715/5701/5685/5686/2033/8453/5716/54583/5693/5721 68 Human_herpesvirus_2 R-HSA-438064 Post NMDA receptor activation events 72/4920 81/10654 6.104694044279016e-16 4.570359177535092e-15 1.7525437447690953e-15 5563/4893/51807/817/347688/53632/10381/107/7846/1741/1739/6196/1740/8874/6197/3845/3265/814/5879/5923/818/5567/5594/51422/5573/2902/6714/10376/6195/2906/801/2891/4747/805/5170/84617/3838/2904/2890/10382/5568/7277/10645/5566/84254/2905/5571/27330/3084/816/5577/5562/10383/84790/5564/5565/5924/7280/5595/815/28964/5575/114/5576/2903/4137/2066/1742/88/1385/808/8536 72 Human_herpesvirus_2 R-HSA-1227986 Signaling by ERBB2 49/4920 50/10654 8.734997706720873e-16 6.470368671645092e-15 2.481118813939095e-15 5295/4893/5335/26469/5578/2064/5753/145957/2534/4145/9542/2885/3845/3265/7314/1839/5290/2065/2069/9101/6714/10000/6233/7525/5580/1729/6464/5782/10193/3084/2886/208/6654/10718/7311/387/1956/2549/11140/8065/685/10273/207/7316/1950/51072/3320/2066/5581 49 Human_herpesvirus_2 R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 49/4920 50/10654 8.734997706720873e-16 6.470368671645092e-15 2.481118813939095e-15 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 49 Human_herpesvirus_2 R-HSA-4420097 VEGFA-VEGFR2 Pathway 84/4920 99/10654 1.1518412855505586e-15 8.487251577740958e-15 3.2545100034946527e-15 5295/4893/857/5335/71/5579/5291/5578/1432/2534/9475/3690/5603/2475/6093/8440/9564/3845/3265/8877/5062/5829/5879/5290/5567/10006/57761/5921/1500/9261/6714/10810/10000/3728/7410/5580/7409/23191/3685/3791/5600/6300/801/253260/805/5170/5590/653361/6461/5747/5568/3315/10451/7867/64223/5566/1003/10163/55845/5063/998/208/79109/2185/387/60/5058/63916/25759/558/1495/1499/4690/207/7422/10458/3708/9047/10768/3320/4846/1398/5296/808 84 Human_herpesvirus_2 R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 52/4920 54/10654 1.330028184607455e-15 9.748897688222184e-15 3.738299113528807e-15 8454/5689/5682/143471/5705/5709/9978/5695/6790/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 52 Human_herpesvirus_2 R-HSA-177929 Signaling by EGFR 48/4920 49/10654 1.8639824827360606e-15 1.359153893661711e-14 5.211793126071222e-15 5295/374/4893/5335/7039/55824/6456/6868/30011/2885/8874/3845/3265/10252/5829/7314/1839/5290/8027/2060/2069/102/6714/9146/6455/1445/6233/29924/255324/5781/6464/5782/5796/998/6654/7311/1956/2549/10253/685/26018/58513/7316/1950/867/5774/10254/6457 48 Human_herpesvirus_2 R-HSA-194138 Signaling by VEGF 89/4920 107/10654 2.0405651824915545e-15 1.4802027230508686e-14 5.6759653289920526e-15 5295/4893/857/5335/71/5579/5291/5578/8828/7423/1432/2534/9475/3690/5603/2475/6093/8440/9564/3845/3265/8877/5062/5829/5879/5290/5567/10006/57761/5921/1500/9261/6714/10810/10000/3728/7410/5580/2324/7409/23191/3685/3791/5600/6300/801/253260/805/5170/5590/653361/6461/5747/7424/5568/3315/10451/7867/64223/5566/1003/10163/55845/5063/998/208/79109/2185/387/60/5058/63916/25759/558/1495/1499/4690/207/7422/10458/3708/9047/10768/3320/4846/1398/5228/5296/808 89 Human_herpesvirus_2 R-HSA-202424 Downstream TCR signaling 83/4920 98/10654 2.137242164950712e-15 1.5423397066654622e-14 5.9142349654089145e-15 5295/8454/5689/4790/5682/5291/7321/143471/5705/5709/5695/4792/3113/5711/5683/5699/5702/3127/7334/3551/5696/5691/7314/5718/8945/5290/5700/122706/5707/23198/23118/8517/5970/9861/5588/5698/5692/5713/5710/916/5719/6233/3932/5170/3123/5706/3122/920/8915/5714/5688/5687/5708/7189/5704/7311/5694/997/1147/5684/5720/6885/5690/5717/9491/6500/10197/919/7316/10213/7322/5715/5701/23291/915/5685/917/5686/5728/5716/5296/5693/5721 83 Human_herpesvirus_2 R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 60/4920 65/10654 2.4944054444115223e-15 1.7908551908595544e-14 6.867189077732126e-15 2074/5982/5431/5435/9978/5433/2965/5439/2967/6117/10714/91603/7314/6118/404672/5438/3978/5985/2068/5984/6233/7874/5424/8451/10450/5434/5436/7515/8450/4331/5425/5111/2966/6119/5427/1161/1642/2071/51426/7311/3980/5983/5432/6917/5440/902/27339/5430/57804/5441/7316/5426/5437/2033/2968/56949/9716/5981/57461/1022 60 Human_herpesvirus_2 R-HSA-5655253 Signaling by FGFR2 in disease 43/4920 43/10654 3.375768869591336e-15 2.411263478279526e-14 9.24619830016961e-15 5295/4893/2250/5335/5431/5435/5433/5439/2885/2252/2253/3845/3265/5290/8823/8074/5438/2249/2248/2247/2246/2251/2963/5434/5436/2263/2962/6654/2549/5432/22916/8822/5440/5430/8817/5441/2254/4686/26281/10818/5437/2255/27006 43 Human_herpesvirus_2 R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 67/4920 75/10654 3.573738734398097e-15 2.5397128061712368e-14 9.738748354491207e-15 5295/374/2250/5291/7039/3082/941/2064/145957/2534/9965/2264/9542/2885/8660/2252/2253/5879/1839/5290/3667/8823/2065/3815/2069/8074/2260/2249/6714/2099/2248/2247/7409/2246/2251/5154/3932/255324/5781/930/2263/4233/8503/5159/3084/10718/5293/1956/2549/8822/685/8817/2100/2254/152831/1950/26281/10818/2261/2255/2066/27006/942/5155/4254/5296/5156 67 Human_herpesvirus_2 R-HSA-69481 G2/M Checkpoints 127/4920 168/10654 4.876298767467305e-15 3.4478880174011244e-14 1.322122472838025e-14 5689/83990/5682/9156/1763/7531/7486/10971/5982/7533/2810/11200/143471/472/5705/5709/4174/5695/84515/4998/5711/4683/10926/5683/990/165918/84126/5699/5702/8924/55388/672/6117/7334/5001/7465/5696/83695/5691/7314/5718/6118/23594/5700/122706/5707/51588/51720/23198/63967/7534/993/116028/983/9861/9656/5698/5692/5985/5713/4175/5710/7157/5984/5719/6233/7158/5884/5810/4999/4172/80010/5000/8318/51512/7532/4173/5706/9133/580/11073/891/641/5714/6119/3364/10524/5688/5687/144715/5708/1111/5704/23595/7311/5983/5694/4176/7529/1017/5684/5720/5883/10111/8317/5690/5717/9491/545/10197/7336/7316/10213/4171/5715/9088/7341/5701/5685/5686/995/5716/5932/79184/7156/5693/5721 127 Human_herpesvirus_2 R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/4920 52/10654 5.848998575425945e-15 4.114873369646394e-14 1.577883773323053e-14 5689/5682/143471/472/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Human_herpesvirus_2 R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 53/4920 56/10654 6.498626126241228e-15 4.54903828836886e-14 1.7443680654647506e-14 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/9861/5698/5692/5713/5710/5719/6233/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 53 Human_herpesvirus_2 R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 49/4920 51/10654 1.2250413607846127e-14 8.532626393524665e-14 3.271909368945548e-14 6227/6206/1965/6234/27335/6191/8668/6224/8662/6202/6218/3921/8665/6208/6203/8666/6222/8667/6231/8663/8894/6207/6233/51386/6188/1968/6230/8669/6194/6232/6193/6210/6229/6205/6235/6223/8664/6187/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 49 Human_herpesvirus_2 R-HSA-4086400 PCP/CE pathway 78/4920 92/10654 1.3430762390532324e-14 9.308449181557056e-14 3.569405325258721e-14 5689/5579/5682/5578/1212/143471/5705/5709/5695/5881/5711/5683/5699/5702/57216/1855/163/5696/5691/4920/7314/5879/5718/161/5700/122706/5707/1856/8322/23198/7471/9861/5698/5692/5713/5710/5719/6233/7474/1857/1213/1211/7855/1175/1173/144165/409/5706/160/5714/5688/5687/4919/5708/5704/7311/387/5694/57154/5684/5720/5690/5717/9491/10197/64750/7316/10213/5216/5715/5701/5685/5686/23513/5716/5693/5721/6259 78 Human_herpesvirus_2 R-HSA-167172 Transcription of the HIV genome 65/4920 73/10654 1.3570686508555268e-14 9.359094143831218e-14 3.588825573950317e-14 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/11198/904/51497/2959/404672/5438/83860/2068/1025/6883/7936/6829/2957/25920/2963/5434/5436/6878/4331/8148/2966/2962/54457/8812/905/2071/6880/6908/6882/2961/5432/22916/6877/6917/5440/902/5430/6749/5441/7469/4686/6872/8731/9150/6879/2958/5437/6827/2968/138474/1022/8178 65 Human_herpesvirus_2 R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 60/4920 66/10654 1.506616343429712e-14 1.0339523925498024e-13 3.964779851130821e-14 5689/5682/7321/3091/143471/5705/5709/9978/5695/5711/5683/5699/7428/5702/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/112399/84962/5706/5714/5688/5687/5708/5704/7311/2034/5694/5684/5720/5690/5717/9491/10197/7316/10213/8994/7322/5715/5701/5685/5686/8453/5716/54583/5693/5721 60 Human_herpesvirus_2 R-HSA-5654743 Signaling by FGFR4 41/4920 41/10654 1.597480241851445e-14 1.0909621163863526e-13 4.1833885665942844e-14 5295/4893/5335/8569/9965/2264/2885/5518/2253/3845/3265/7314/5515/5290/8823/5594/8074/2249/6714/2247/6233/2246/2251/5781/6464/673/6654/7311/2549/5595/5516/8822/10253/8817/10817/2254/7316/152831/26281/10818/867 41 Human_herpesvirus_2 R-HSA-74751 Insulin receptor signalling cascade 51/4920 54/10654 2.7614543898738657e-14 1.876716575642433e-13 7.196431981786773e-14 5295/3643/4893/2250/5291/9965/2264/3630/2885/8660/9846/2252/2253/3845/3265/2323/54106/5290/3667/8823/5594/8074/57761/2260/2249/2248/2247/2246/2251/5781/30849/5170/6464/2322/2263/208/6654/2549/5595/8822/8817/2254/152831/5289/26281/10818/2261/2255/27006/5296/2887 51 Human_herpesvirus_2 R-HSA-5674135 MAP2K and MAPK activation 40/4920 40/10654 3.4745195260268756e-14 2.3499165876510267e-13 9.010958343624239e-14 4893/71/84292/5908/22866/5605/5037/2244/54756/3690/408/5894/8826/4140/3845/3265/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/28956/283455/3674/409/673/7450/60/7529/5595/5604/54518/10256/8649/5906 40 Human_herpesvirus_2 R-HSA-5610787 Hedgehog 'off' state 91/4920 113/10654 4.863596370442873e-14 3.27357448010578e-13 1.2552804397398101e-13 8454/5689/5682/1452/51684/143471/10381/5705/5709/9978/5695/107/5711/7846/5683/5699/5702/83737/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/112/5573/2737/5727/8650/111/9861/2932/5698/5692/5713/10376/5710/5719/6233/23322/196883/115/84617/54903/10382/79809/5568/7277/5706/113/5714/5566/5688/5687/5708/5577/5704/7311/10383/84790/5694/7280/109/5684/5720/2735/5575/5690/5717/9491/6500/114/7289/10197/108/7316/10213/2778/5715/5701/5576/5685/5686/5716/8481/5693/5721 91 Human_herpesvirus_2 R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 47/4920 49/10654 5.359754699628551e-14 3.5902663059712787e-13 1.3767186586807157e-13 9134/57060/2810/1869/6790/25904/1647/8900/55571/55835/57472/144455/85456/29883/1263/7027/7832/898/5934/890/10769/983/7157/5325/79733/1820/4869/4850/891/5111/246175/4848/23019/1874/1017/25946/4849/1027/9337/1026/5933/28984/2033/995/10498/581/3276 47 Human_herpesvirus_2 R-HSA-5689880 Ub-specific processing proteases 156/4920 220/10654 5.6677365624459136e-14 3.752769815465018e-13 1.4390320345016233e-13 5689/645836/5682/79594/7419/10474/7375/9817/91833/6478/3091/143471/100287513/5705/11274/55031/8239/5709/5695/4792/9986/11047/4609/392188/4194/4089/100287144/5711/4088/5683/408/64135/5699/8724/8312/100287327/5702/8900/8975/57599/377630/6881/51616/728386/1540/100287404/5696/5691/7314/5718/90865/2648/5700/122706/5707/8737/55611/100287364/57646/23198/63967/9101/8517/993/890/7417/4092/1643/9861/23586/81847/64426/100287441/6502/5698/9146/5692/5713/5710/10454/7157/10869/9958/5719/6233/100287478/9804/23770/8607/7874/100287178/100287238/10600/23326/51651/8237/4303/409/330/5706/27005/7416/25862/9738/84132/5714/79589/5688/9097/5687/5708/4087/63891/84749/7189/5704/7311/367/5694/9960/23358/23032/5684/8295/5720/7186/6885/991/5690/2625/5717/9491/4086/1080/10197/64750/7316/10213/8678/9100/5715/3416/5701/329/9099/5685/5686/5728/5716/9736/5693/154/10254/5721/100287205/4193 156 Human_herpesvirus_2 R-HSA-169911 Regulation of Apoptosis 50/4920 53/10654 5.682765720561313e-14 3.752769815465018e-13 1.4390320345016233e-13 5689/5682/4976/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Human_herpesvirus_2 R-HSA-2428924 IGF1R signaling cascade 50/4920 53/10654 5.682765720561313e-14 3.752769815465018e-13 1.4390320345016233e-13 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/2323/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/8471/2246/2251/5781/30849/5170/6464/2322/2263/3481/208/6654/2549/3480/8822/8817/2254/152831/5289/26281/10818/2261/2255/27006/3479/5296 50 Human_herpesvirus_2 R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 79/4920 95/10654 8.090917147542084e-14 5.293123367550897e-13 2.0296939228954565e-13 8454/3725/9252/4790/1848/4792/59307/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/5601/5606/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/51295/79155/8651/7867/5602/57162/695/7189/7311/6416/5595/5516/1147/1845/6885/5604/6500/246330/7099/4615/7316/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/57161 79 Human_herpesvirus_2 R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 79/4920 95/10654 8.090917147542084e-14 5.293123367550897e-13 2.0296939228954565e-13 8454/3725/9252/4790/1848/4792/59307/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/5601/5606/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/51295/79155/8651/7867/5602/57162/695/7189/7311/6416/5595/5516/1147/1845/6885/5604/6500/246330/7099/4615/7316/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/57161 79 Human_herpesvirus_2 R-HSA-1852241 Organelle biogenesis and maintenance 199/4920 296/10654 1.0886100636459516e-13 7.088623670252708e-13 2.7181940389690835e-13 55763/5563/79738/79867/55735/79718/7531/11190/203068/54801/51807/85302/347688/79441/53632/10381/5116/3313/5048/10576/5469/10989/22832/60412/192668/8655/83658/89891/9702/132320/1432/1387/25813/7846/7840/2101/11064/84902/2847/10499/23054/5518/1386/55835/85441/3054/23332/7019/93323/814/10575/1454/23408/51422/10013/54806/5465/91147/54927/983/79959/2747/5310/4208/6604/8729/10376/10540/11336/117177/57545/55902/26005/54930/54820/23322/6742/378/56623/5600/1453/6300/801/9793/4218/133522/140735/64216/805/6102/84617/4899/5442/11258/22981/8636/54903/80776/3842/3418/7532/55125/10382/23082/6753/79809/23410/121441/7277/55112/26146/8834/9814/4209/23354/2553/146057/9738/1639/55722/4957/5566/5571/2551/7283/4580/22919/27077/22994/4867/6648/1069/10651/5577/10383/5347/403/84790/22948/80184/22897/5564/51106/23373/5565/5108/261734/2746/57787/7280/10806/9657/1778/55770/23265/115106/10694/22995/55559/8841/10142/10640/51134/95681/200186/79989/7203/1781/80321/8766/9611/23409/79598/54205/149371/10121/347240/84131/6950/55212/3320/79600/10733/6256/4751/10498/80254/1385/200894/26123/808/54536/9662/55142/8648/8481/51259/55755/10891 199 Human_herpesvirus_2 R-HSA-2428928 IRS-related events triggered by IGF1R 49/4920 52/10654 1.1680685913737262e-13 7.570814944088966e-13 2.903094452244641e-13 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/2323/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/8471/2246/2251/5781/30849/5170/2322/2263/3481/208/6654/2549/3480/8822/8817/2254/152831/5289/26281/10818/2261/2255/27006/3479/5296 49 Human_herpesvirus_2 R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 80/4920 97/10654 1.389254311010691e-13 8.962931038778651e-13 3.4369134058474526e-13 8454/3725/9252/4790/1848/4792/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/5601/5606/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/30849/5608/4791/1846/3665/351/8411/51295/79155/7867/5602/57162/7189/7311/6416/51284/5595/5516/1147/1845/6885/5604/6500/246330/7099/4615/7316/4205/5289/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 80 Human_herpesvirus_2 R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 78/4920 94/10654 1.471088899657969e-13 9.447359906060351e-13 3.622671843677278e-13 8454/3725/9252/4790/7321/1848/4792/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/5601/5606/8737/1849/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/2353/8772/5600/5608/4791/1846/3665/351/330/7098/79155/7867/5602/7189/7311/6416/5595/5516/1147/1845/6885/5604/6500/7316/4205/4793/3146/7322/329/466/23291/6288/2002/6285/5609/1385/5599 78 Human_herpesvirus_2 R-HSA-6782135 Dual incision in TC-NER 59/4920 66/10654 1.5474136149937044e-13 9.869354893595986e-13 3.784489470476656e-13 2074/5982/5431/5435/9978/5433/2965/5439/2067/2967/6117/10714/91603/7314/6118/404672/5438/5985/2068/5984/6233/7874/5424/8451/10450/5434/5436/8450/4331/5425/5111/2966/6119/5427/1161/1642/2071/51426/7311/5983/5432/6917/5440/902/27339/5430/57804/5441/2072/7316/5426/5437/2033/2968/56949/9716/5981/57461/1022 59 Human_herpesvirus_2 R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 72/4920 85/10654 1.564997704555935e-13 9.869354893595986e-13 3.784489470476656e-13 8454/3725/9252/4790/1848/4792/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/5601/5606/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/51295/79155/7867/5602/57162/7189/7311/6416/5595/5516/1147/1845/6885/5604/6500/246330/4615/7316/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 72 Human_herpesvirus_2 R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 72/4920 85/10654 1.564997704555935e-13 9.869354893595986e-13 3.784489470476656e-13 8454/3725/9252/4790/1848/4792/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/5601/5606/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/51295/79155/7867/5602/57162/7189/7311/6416/5595/5516/1147/1845/6885/5604/6500/246330/4615/7316/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 72 Human_herpesvirus_2 R-HSA-975871 MyD88 cascade initiated on plasma membrane 72/4920 85/10654 1.564997704555935e-13 9.869354893595986e-13 3.784489470476656e-13 8454/3725/9252/4790/1848/4792/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/5601/5606/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/51295/79155/7867/5602/57162/7189/7311/6416/5595/5516/1147/1845/6885/5604/6500/246330/4615/7316/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 72 Human_herpesvirus_2 R-HSA-3371453 Regulation of HSF1-mediated heat shock response 61/4920 69/10654 1.9161456730883982e-13 1.2029614091137927e-12 4.612859538707023e-13 23165/573/7531/9530/348995/472/57122/3313/23511/3305/23279/23225/3309/9531/3306/9972/23411/8021/6117/3312/55746/51182/3303/6118/5594/3308/10049/3337/10762/9261/79902/9883/2932/6396/129401/3297/4928/5903/55706/7175/4927/6119/57805/3310/7266/8086/3304/5595/81929/9631/545/79023/23636/10808/53371/9532/9688/6767/22824/9529/8480 61 Human_herpesvirus_2 R-HSA-4641257 Degradation of AXIN 51/4920 55/10654 2.0880474525350168e-13 1.3050296578343854e-12 5.004249063876215e-13 5689/5682/143471/5705/5709/5695/5711/5683/5699/8312/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/81847/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_herpesvirus_2 R-HSA-1236975 Antigen processing-Cross presentation 81/4920 99/10654 2.3179279333282936e-13 1.442266269626494e-12 5.53049471811663e-13 8773/5689/5682/3107/811/143471/5705/5709/5695/567/3106/5711/5683/5699/5702/3133/3551/5696/5691/7314/5718/10952/5700/122706/5707/23198/6892/8517/6810/9861/5698/5692/5713/5710/5719/6233/3685/3135/653361/6890/2209/5706/9554/29927/5714/5688/5687/5708/2923/695/9902/5704/4012/7311/5694/8673/3105/1147/5684/5720/5690/5717/9491/10197/7099/4615/6891/7316/10213/5715/5701/9341/5685/5686/114609/948/5716/3134/7097/5693/5721 81 Human_herpesvirus_2 R-HSA-6783783 Interleukin-10 signaling 45/4920 47/10654 2.336261798692191e-13 1.4472418221987024e-12 5.549573904671716e-13 729230/7124/1437/3593/5743/941/3383/6349/3576/2920/1435/7133/3606/6347/3588/3569/3592/3587/6367/3976/3627/7076/7850/7297/3557/6351/6774/1440/3552/3716/1234/3586/3554/2208/3553/1230/2919/2357/6352/6348/6364/7132/942/6363/5724 45 Human_herpesvirus_2 R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 77/4920 93/10654 2.6688558922937416e-13 1.6316149559874402e-12 6.256568628222516e-13 8454/3725/9252/4790/1848/4792/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/5601/5606/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/1846/3665/351/51295/79155/7867/5602/57162/7189/7311/6416/51284/5595/5516/1147/1845/6885/5604/6500/246330/7099/4615/7316/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 77 Human_herpesvirus_2 R-HSA-442755 Activation of NMDA receptors and postsynaptic events 77/4920 93/10654 2.6688558922937416e-13 1.6316149559874402e-12 6.256568628222516e-13 5563/4893/51807/817/347688/53632/10381/107/7846/1741/1739/6196/1740/8874/6197/8825/3845/3265/814/5879/5923/818/5567/5594/51422/5573/2902/6714/10376/6195/2906/801/2891/4747/805/5170/84617/3838/8573/2904/2890/10382/5568/7277/10645/55327/5566/84254/2905/5571/27330/3084/816/5577/5562/10383/84790/5564/5565/5924/7280/5595/64130/815/28964/5575/114/5576/2903/4137/2066/9647/1742/88/1385/808/8536 77 Human_herpesvirus_2 R-HSA-975155 MyD88 dependent cascade initiated on endosome 77/4920 93/10654 2.6688558922937416e-13 1.6316149559874402e-12 6.256568628222516e-13 8454/3725/9252/4790/1848/4792/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/5601/5606/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/1846/3665/351/51295/79155/7867/5602/57162/7189/7311/6416/51284/5595/5516/1147/1845/6885/5604/6500/246330/7099/4615/7316/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 77 Human_herpesvirus_2 R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 71/4920 84/10654 2.8966666377744183e-13 1.7631883882105156e-12 6.761098330732051e-13 10445/5982/6613/9978/85015/10980/2965/10987/2067/2967/6612/6117/7334/10714/7314/6118/404672/86/3978/1643/5985/10920/2068/5984/6233/93973/8607/5424/5886/8451/8554/7515/8450/4331/5425/5111/2966/6119/5427/1642/142/125476/2071/1069/7329/51426/2873/7311/3980/60/8533/5983/51138/7528/9318/902/57804/7336/2072/7316/64708/5426/283899/7341/10401/54617/2968/5887/5981/1022/7508 71 Human_herpesvirus_2 R-HSA-2408522 Selenoamino acid metabolism 93/4920 118/10654 2.971469123508359e-13 1.800890377883854e-12 6.905669870080943e-13 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/3176/6208/6170/7296/6203/6147/4143/6222/4837/6134/60678/6155/6231/6142/9061/23521/6207/6233/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/11185/51065/6141/6123/875/6164/6209/11224/6165/6130/6204/6228/7965/6124/6189/6135/6201/6161/6133 93 Human_herpesvirus_2 R-HSA-9614085 FOXO-mediated transcription 58/4920 65/10654 3.0181661329686107e-13 1.821307149205196e-12 6.983959745072556e-13 2308/857/2290/65018/57060/356/10971/7295/2810/4089/1647/1387/4088/10628/4801/3630/56729/23411/2538/7534/5934/3484/5443/8850/10000/3066/604/2645/5105/7532/4303/23410/4287/4800/901/9314/10370/2908/6794/4852/6648/4087/208/25942/7529/27113/2309/10018/4802/207/1027/6720/1649/114907/1026/2033/3065/10891 58 Human_herpesvirus_2 R-HSA-176187 Activation of ATR in response to replication stress 37/4920 37/10654 3.572598202268748e-13 2.146625529260192e-12 8.2314212024263e-13 5982/4174/84515/4998/10926/990/84126/55388/6117/5001/6118/23594/63967/993/5985/4175/5984/5884/5810/4999/4172/5000/8318/4173/6119/3364/144715/1111/23595/5983/4176/1017/5883/8317/545/4171/995 37 Human_herpesvirus_2 R-HSA-180585 Vif-mediated degradation of APOBEC3G 50/4920 54/10654 4.2199157354154684e-13 2.5139923530134703e-12 9.640121052908797e-13 5689/5682/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/8065/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Human_herpesvirus_2 R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 50/4920 54/10654 4.2199157354154684e-13 2.5139923530134703e-12 9.640121052908797e-13 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/2323/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/8471/2246/2251/5781/30849/5170/6464/2322/2263/3481/208/6654/2549/3480/8822/8817/2254/152831/5289/26281/10818/2261/2255/27006/3479/5296 50 Human_herpesvirus_2 R-HSA-5678895 Defective CFTR causes cystic fibrosis 55/4920 61/10654 4.547239347818558e-13 2.697514867349992e-12 1.034385400262027e-12 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/5696/5691/7314/5718/5700/122706/5707/10956/79139/91445/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 55 Human_herpesvirus_2 R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 76/4920 92/10654 4.830982023524599e-13 2.8537446552465984e-12 1.0942930632900489e-12 8454/3725/9252/4790/1848/4792/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/5601/5606/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/1846/351/51295/79155/7867/5602/57162/7189/7311/6416/51284/5595/5516/1147/1845/6885/5604/6500/246330/7099/4615/7316/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 76 Human_herpesvirus_2 R-HSA-5654736 Signaling by FGFR1 47/4920 50/10654 4.916685579724953e-13 2.892167988073502e-12 1.1090268224943503e-12 5295/4893/2250/5335/8569/2885/5518/2253/3845/3265/7314/5515/5290/23768/5594/8074/2260/2249/6714/2248/2247/6233/2246/2251/200734/5781/6464/673/23767/6654/7311/53834/2549/5595/5516/8822/10253/8817/10817/2254/7316/26281/10818/867/2255/27006/161742 47 Human_herpesvirus_2 R-HSA-76002 Platelet activation, signaling and aggregation 178/4920 262/10654 5.266339935931203e-13 3.084885318118696e-12 1.1829259490530339e-12 5295/2788/5777/5579/2153/5770/5291/7042/64805/2770/5175/5578/5908/3082/388/29106/7423/1432/3920/374354/2244/3309/2534/3690/408/2768/2782/87/2776/5894/10487/2885/7040/9564/5874/54863/350/7043/2773/5879/5054/2787/5099/1072/5290/7018/5340/5336/813/7094/5594/10681/7414/10490/7534/6810/10125/2792/6714/6694/7273/22927/1191/146850/27154/226/5588/2335/5294/2785/2783/2784/1445/8525/5478/2771/94121/7410/5580/2266/7409/5154/3932/7076/2243/801/5781/2791/805/5170/5590/351/6464/135228/5747/3937/7424/2316/3674/409/7277/10451/334/1277/150/335/51706/308/6850/8503/197/4067/81/998/3481/2786/54495/6654/5473/8407/7450/387/29789/10916/5595/7066/151/5321/54331/5005/59345/1606/207/26090/7422/51764/94235/3708/5196/3827/54518/1950/55970/2621/5216/2767/5768/346562/710/152/6647/4352/27040/2793/23533/5265/7078/2/1398/948/88/1675/10235/5906/3479/5155/5296/5581/51368/808/213/5660/7057/1278/9002/2207/6814/2790 178 Human_herpesvirus_2 R-HSA-450294 MAP kinase activation 57/4920 64/10654 5.875789024645228e-13 3.4133214251051116e-12 1.3088676141380503e-12 8454/3725/9252/4790/1848/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/5601/5606/1849/5594/23118/8517/5528/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/1846/79155/7867/5602/7189/7311/6416/5595/5516/1147/1845/6885/5604/6500/7316/4205/466/23291/2002/5609/1385/5599 57 Human_herpesvirus_2 R-HSA-4608870 Asymmetric localization of PCP proteins 57/4920 64/10654 5.875789024645228e-13 3.4133214251051116e-12 1.3088676141380503e-12 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/57216/5696/5691/7314/5718/5700/122706/5707/1856/8322/23198/9861/5698/5692/5713/5710/5719/6233/7474/7855/144165/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/23513/5716/5693/5721 57 Human_herpesvirus_2 R-HSA-72766 Translation 194/4920 291/10654 7.596354666918597e-13 4.394585344498362e-12 1.685141748642229e-12 6158/6138/5464/6227/6206/1965/6234/27335/6191/6128/6132/1917/84545/6129/1915/80222/6176/8668/6224/6146/6154/8662/26986/6202/64949/65003/55052/6169/6175/6218/6173/64968/6167/116832/28977/6156/6143/1973/124995/28973/51116/6139/6745/64975/3921/8665/10667/65005/84340/6208/6170/92935/6203/51253/10952/6147/8666/6222/64432/4528/8667/6727/7818/6184/79731/58477/2935/6134/55699/6155/55157/10240/6729/6231/6142/7458/8663/23521/23107/8894/65008/1981/85476/6185/6207/64978/1977/6726/6233/28957/51386/6188/26589/1978/64965/7284/200916/6122/1968/6230/8669/6194/2107/6166/1938/1650/1983/6136/6125/1937/23395/6232/6160/6748/29927/1933/6193/6210/6229/6205/54148/28972/64976/140801/23438/79587/6235/51263/6181/740/8893/1975/7311/6223/25873/8664/6730/23708/9045/6187/6168/6157/6137/1974/55037/6144/10352/6182/9349/4736/8891/327/51121/65993/6159/56945/6217/1936/6152/79590/51065/6141/10480/6123/1967/6164/63931/8661/64963/9669/6209/1964/11224/6165/6130/8890/6204/64969/51081/6228/7965/6124/90480/2193/3646/6189/9789/6135/6201/6161/51649/54998/8892/6133 194 Human_herpesvirus_2 R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 36/4920 36/10654 7.766963085931493e-13 4.456454229632824e-12 1.708865907603564e-12 4893/71/5908/22866/5605/5037/2244/3690/408/5894/8826/4140/3845/3265/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/283455/3674/409/673/7450/60/7529/5595/5604/54518/10256/5906 36 Human_herpesvirus_2 R-HSA-76046 RNA Polymerase III Transcription Initiation 36/4920 36/10654 7.766963085931493e-13 4.456454229632824e-12 1.708865907603564e-12 55718/2976/5435/9328/84265/55290/10302/9330/2972/2975/10622/7702/661/55814/11128/9533/5434/2971/10623/112495/9329/6621/6908/6619/51728/171568/10621/6618/5440/5451/6617/5441/51082/55703/27297/5437 36 Human_herpesvirus_2 R-HSA-195258 RHO GTPase Effectors 214/4920 327/10654 8.431242446800284e-13 4.8178528267430195e-12 1.847447324540556e-12 55839/11130/71/6249/51517/5579/9735/7531/5526/51807/10971/5578/9212/347688/388/7533/2810/147841/348995/10381/57122/6280/1780/23122/3688/5048/57405/8655/10094/23279/1432/2017/2491/7846/79784/9475/1060/4628/11004/8976/1855/2885/23433/6093/9184/8826/10499/5518/23332/25909/10726/81930/5062/55746/5879/5515/85415/25/79682/1072/10403/4638/25936/4659/10093/1856/10006/4771/389/5594/3619/64105/7534/332/5528/6714/79902/3796/5519/81565/999/89953/10810/91687/10376/11113/83540/5580/9055/128239/1857/23191/7514/54820/1729/6396/5600/801/64946/9793/30849/10109/5586/140735/5500/4221/805/3831/220134/5170/84617/4928/5590/5903/653361/55055/5747/80776/1783/401541/2316/7532/10382/10627/79172/7277/79980/6232/5501/6279/54821/10092/9183/10163/1062/699/752/22919/55845/5063/3895/5529/51143/998/695/10788/10097/57120/367/10383/5347/387/60/84790/84643/5058/7280/4629/7529/5595/64130/1778/5516/5905/81929/27035/54908/55143/1495/1499/5525/4690/1058/991/79019/4627/348235/80152/10458/1063/3985/8379/1027/1080/23421/55920/79023/6242/1781/10398/4085/5289/5585/5216/10552/55166/4637/995/79003/23028/1742/5527/10096/7454/701/23380/9928/29941/3799/103910/57551/5300/808/10095 214 Human_herpesvirus_2 R-HSA-168898 Toll-like Receptor Cascades 115/4920 155/10654 8.826149431625509e-13 5.023011871656794e-12 1.9261173342443346e-12 8454/3725/10695/9252/4790/7321/1848/1785/6280/4792/59307/177/1432/2244/3654/6196/1759/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/5601/5606/8737/5336/1849/29110/5594/4214/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/51311/2266/2353/2243/8772/5600/5781/30849/5608/4791/671/1846/3665/351/7184/3684/8411/330/51295/7098/338/79155/6279/8651/26052/7867/5602/57162/695/7189/81622/7311/6416/51284/5595/5516/1147/1845/6885/5604/6500/246330/7099/4615/7316/4205/5289/4793/3146/7322/329/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/3929/57161/3689 115 Human_herpesvirus_2 R-HSA-4615885 SUMOylation of DNA replication proteins 43/4920 45/10654 1.0142800151945312e-12 5.748955551709893e-12 2.2044867153173272e-12 23165/9212/348995/6613/57122/23511/6790/23279/23225/9972/6612/8021/55746/7150/51588/3619/7153/332/10762/79902/9883/7155/6396/129401/4928/5903/55706/7175/5111/4927/8086/7329/5905/81929/55143/9631/79023/23636/53371/9688/7341/10401/8480 43 Human_herpesvirus_2 R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 99/4920 129/10654 1.0255187366268633e-12 5.789218674506487e-12 2.2199259578934646e-12 8454/3725/9252/4790/7321/1848/1785/4792/59307/177/1432/3654/6196/1759/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/5601/5606/8737/5336/1849/29110/5594/4214/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/2353/8772/5600/5781/5608/4791/671/1846/3665/351/3684/330/51295/79155/8651/26052/7867/5602/57162/695/7189/7311/6416/5595/5516/1147/1845/6885/5604/6500/246330/7099/4615/7316/4205/4793/3146/7322/329/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/3929/57161/3689 99 Human_herpesvirus_2 R-HSA-5654741 Signaling by FGFR3 39/4920 40/10654 1.6674348049499448e-012 9.37513544951776e-12 3.594976751318841e-12 5295/4893/2250/5335/8569/2885/5518/2253/3845/3265/7314/5515/5290/8823/5594/8074/2249/6714/2247/6233/2246/5781/6464/673/6654/7311/2549/5595/5516/8822/10253/8817/10817/2254/7316/26281/10818/2261/867 39 Human_herpesvirus_2 R-HSA-5387390 Hh mutants abrogate ligand secretion 53/4920 59/10654 1.7551631356675087e-12 9.828913559738048e-12 3.768981891328124e-12 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/9861/5698/5692/5713/5710/5719/6233/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 53 Human_herpesvirus_2 R-HSA-112399 IRS-mediated signalling 45/4920 48/10654 2.0586968836642568e-12 1.1437204909245871e-11 4.385695115575484e-12 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/2323/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/2246/2251/5781/30849/5170/2322/2263/208/6654/2549/8822/8817/2254/152831/5289/26281/10818/2261/2255/27006/5296 45 Human_herpesvirus_2 R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 45/4920 48/10654 2.0586968836642568e-12 1.1437204909245871e-11 4.385695115575484e-12 5295/5777/1437/5291/6776/3558/3717/2534/3563/2885/9846/1399/7314/5290/1439/7534/3718/3567/6233/7525/7409/6777/5781/3562/6464/1438/6850/5566/8503/2889/4067/3636/6654/3716/7311/5293/3561/3568/7316/3560/3055/867/1398/5296/3559 45 Human_herpesvirus_2 R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 79/4920 98/10654 2.0946788832859767e-12 1.1545474159843966e-11 4.427211895880018e-12 8454/3725/9252/4790/1848/4792/59307/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/5601/5606/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/51295/79155/8651/7867/5602/57162/695/7189/7311/6416/5595/5516/1147/1845/6885/5604/6500/246330/7099/4615/7316/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/57161 79 Human_herpesvirus_2 R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 79/4920 98/10654 2.0946788832859767e-12 1.1545474159843966e-11 4.427211895880018e-12 8454/3725/9252/4790/1848/4792/59307/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/5601/5606/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/51295/79155/8651/7867/5602/57162/695/7189/7311/6416/5595/5516/1147/1845/6885/5604/6500/246330/7099/4615/7316/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/57161 79 Human_herpesvirus_2 R-HSA-1632852 Macroautophagy 77/4920 95/10654 2.3432213578435537e-12 1.2864744709729315e-11 4.933097595460113e-12 5563/65018/1459/27243/9140/8878/1460/53632/84938/115201/9474/8655/1457/10325/29082/9776/55054/55062/2475/84557/10670/3312/64121/7314/64422/60673/9821/51422/7249/10533/91782/440738/6714/8408/84971/123/55669/6233/9804/30849/57521/140735/28956/7405/79643/389541/79065/22863/58528/7416/26100/64223/5571/128866/6009/55004/7311/5562/11345/55626/5564/5565/7248/11337/10452/153129/7316/83734/11152/5289/8678/56993/8649/81631/10542/23710/23192 77 Human_herpesvirus_2 R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 57/4920 65/10654 2.6236352127841337e-12 1.434800506991323e-11 5.501866605756201e-12 3725/4436/472/5431/5435/5433/2965/5439/672/2967/1386/11198/904/51497/2176/404672/5438/1643/9656/2177/2068/7157/1025/2353/7936/6829/25920/2963/5434/5436/4292/4331/2966/2962/8812/905/1111/2071/55215/5432/6917/5440/8621/902/5430/6749/545/5441/7469/5395/9150/5437/51755/6827/2968/1022/8178 57 Human_herpesvirus_2 R-HSA-9612973 Autophagy 92/4920 119/10654 3.0811618271015247e-12 1.6784539135961615e-11 6.436176661158213e-12 5563/2670/65018/1459/1915/27243/9140/8878/1460/53632/84938/5116/115201/9474/8655/1457/3043/3920/10325/29082/9776/55054/55062/2475/84557/10670/3312/11315/64121/7314/64422/60673/9821/51422/7249/10533/10013/91782/440738/6714/8408/89853/84971/123/55669/6233/9804/30849/57521/140735/28956/7405/79643/389541/79065/22863/58528/7416/26100/64223/5571/128866/6009/3326/55004/7311/5562/93343/11345/55626/7251/5564/5565/7248/11337/10452/1080/153129/7316/83734/11152/5289/8678/56993/8649/3320/81631/10542/23710/200894/7431/23192 92 Human_herpesvirus_2 R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 65/4920 77/10654 3.369402050479477e-12 1.828357701810569e-11 7.010995698672106e-12 1912/23165/7486/6045/80012/10274/348995/6613/57122/23511/1911/6672/23279/23225/165918/57332/5371/8924/672/9972/6612/8021/6117/55746/79677/51564/51588/10762/79902/9656/9883/84733/9063/6396/129401/7703/6015/8554/4928/5903/55706/7175/1029/8535/5885/641/4927/8243/142/1069/8086/7329/648/81929/9631/79023/23636/10735/53371/6996/9688/7341/9126/8480/7508 65 Human_herpesvirus_2 R-HSA-5654727 Negative regulation of FGFR2 signaling 34/4920 34/10654 3.669791141070492e-12 1.9836708870651305e-11 7.60655753686629e-12 2250/8569/2885/5518/2252/2253/7314/5515/8823/5594/8074/2249/6714/2248/2247/6233/2246/2251/5781/673/2263/7311/5595/5516/8822/10253/8817/2254/7316/26281/10818/867/2255/27006 34 Human_herpesvirus_2 R-HSA-112382 Formation of RNA Pol II elongation complex 54/4920 61/10654 4.2844917882876075e-12 2.2981948289665326e-11 8.812626787766403e-12 5431/5435/5433/2965/5439/2967/11198/904/51497/4300/80349/404672/5438/2068/1025/23168/55677/7936/6829/123169/25920/85403/2963/5434/5436/9646/79577/4331/2966/2962/4298/8812/905/2071/27125/5432/22916/55840/6917/5440/902/6830/5430/6749/5441/7469/4686/9150/54623/5437/6827/2968/1022/8178 54 Human_herpesvirus_2 R-HSA-75955 RNA Polymerase II Transcription Elongation 54/4920 61/10654 4.2844917882876075e-12 2.2981948289665326e-11 8.812626787766403e-12 5431/5435/5433/2965/5439/2967/11198/904/51497/4300/80349/404672/5438/2068/1025/23168/55677/7936/6829/123169/25920/85403/2963/5434/5436/9646/79577/4331/2966/2962/4298/8812/905/2071/27125/5432/22916/55840/6917/5440/902/6830/5430/6749/5441/7469/4686/9150/54623/5437/6827/2968/1022/8178 54 Human_herpesvirus_2 R-HSA-168325 Viral Messenger RNA Synthesis 41/4920 43/10654 4.3844463015563e-12 2.342833901594969e-11 8.98379917152958e-12 23165/348995/57122/5431/23511/5435/5433/23279/23225/5439/9972/8021/55746/5438/10762/79902/9883/6396/129401/4928/2963/5434/5903/55706/7175/5436/4927/2962/8086/5432/81929/5440/9631/5430/79023/5441/23636/53371/9688/5437/8480 41 Human_herpesvirus_2 R-HSA-111885 Opioid Signalling 74/4920 91/10654 4.6168061524555945e-12 2.4576154423717996e-11 9.423938914358027e-12 2788/5331/2770/817/5578/5530/107/4988/2782/5499/5518/814/2773/5515/2787/818/5567/5594/10681/112/5573/5528/111/5443/2792/5519/2785/2783/2784/2771/5580/5153/196883/115/801/2791/805/3838/5568/113/10645/5566/84254/23236/816/2786/5577/1020/109/5516/5533/815/5321/54331/5575/59345/5532/51764/94235/114/3708/108/2779/5173/55970/10768/346562/2793/5576/5534/1385/808/5137/2790 74 Human_herpesvirus_2 R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 49/4920 54/10654 5.061245073548321e-12 2.683993599608958e-11 1.0292005532335103e-11 2074/5431/5435/9978/5433/10980/2965/5439/10987/2967/91603/7314/404672/5438/10920/2068/6233/7874/8451/10450/5434/5436/8450/4331/2966/1161/1642/2071/2873/7311/8533/5432/51138/9318/6917/5440/902/27339/5430/5441/7316/64708/5437/2033/2968/56949/9716/57461/1022 49 Human_herpesvirus_2 R-HSA-166166 MyD88-independent TLR4 cascade 79/4920 99/10654 5.687212571669638e-12 2.993269774562968e-11 1.1477951767121151e-11 8454/3725/9252/4790/7321/1848/4792/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/5601/5606/8737/1849/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/2353/8772/5600/5781/5608/4791/1846/3665/351/330/79155/7867/5602/7189/7311/6416/5595/5516/1147/1845/6885/5604/6500/7099/7316/4205/4793/3146/7322/329/466/23291/6288/2002/6285/5609/1385/5599 79 Human_herpesvirus_2 R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 79/4920 99/10654 5.687212571669638e-12 2.993269774562968e-11 1.1477951767121151e-11 8454/3725/9252/4790/7321/1848/4792/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/5601/5606/8737/1849/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/2353/8772/5600/5781/5608/4791/1846/3665/351/330/79155/7867/5602/7189/7311/6416/5595/5516/1147/1845/6885/5604/6500/7099/7316/4205/4793/3146/7322/329/466/23291/6288/2002/6285/5609/1385/5599 79 Human_herpesvirus_2 R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 46/4920 50/10654 6.9303866640061905e-12 3.6339106103403246e-11 1.3934544445665905e-11 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/2209/5706/5714/5688/5687/5708/9902/5704/5694/5684/5720/5690/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 46 Human_herpesvirus_2 R-HSA-5655302 Signaling by FGFR1 in disease 37/4920 38/10654 7.496331962987823e-12 3.91599430902349e-11 1.5016218778962253e-11 5295/4893/11052/2250/5335/9530/613/6776/11064/2885/9846/2253/3845/3265/7750/8805/26127/5290/8074/2260/2249/399687/2247/2246/2251/6777/1523/9208/6774/6772/6654/11160/2549/8822/2254/26281/10818 37 Human_herpesvirus_2 R-HSA-113418 Formation of the Early Elongation Complex 33/4920 33/10654 7.975619338921618e-12 4.1202461529484374e-11 1.5799440135366184e-11 5431/5435/5433/2965/5439/2967/51497/404672/5438/2068/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/7469/4686/9150/5437/6827/2968/1022 33 Human_herpesvirus_2 R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 33/4920 33/10654 7.975619338921618e-12 4.1202461529484374e-11 1.5799440135366184e-11 5431/5435/5433/2965/5439/2967/51497/404672/5438/2068/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/7469/4686/9150/5437/6827/2968/1022 33 Human_herpesvirus_2 R-HSA-1839126 FGFR2 mutant receptor activation 33/4920 33/10654 7.975619338921618e-12 4.1202461529484374e-11 1.5799440135366184e-11 2250/5431/5435/5433/5439/2252/2253/8823/8074/5438/2249/2248/2247/2246/2251/2963/5434/5436/2263/2962/5432/22916/8822/5440/5430/8817/5441/2254/4686/26281/5437/2255/27006 33 Human_herpesvirus_2 R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 40/4920 42/10654 9.099962395094446e-12 4.6666473820997165e-11 1.7894662893765827e-11 23165/348995/57122/23511/81608/23279/23225/9972/8021/55746/53981/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/7884/4927/10898/10482/51692/8086/22916/81929/9631/29894/79023/23636/4686/8189/53371/9688/10189/8480/55339 40 Human_herpesvirus_2 R-HSA-3928662 EPHB-mediated forward signaling 40/4920 42/10654 9.099962395094446e-12 4.6666473820997165e-11 1.7894662893765827e-11 71/1947/2051/10094/2050/2047/2534/9475/1948/8976/6093/8997/3265/5879/1072/10093/5921/6453/2902/6714/7525/10109/2904/5747/7074/1949/2049/10092/4067/998/2048/10097/387/60/5058/3985/6383/10552/10096/10095 40 Human_herpesvirus_2 R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 61/4920 72/10654 1.1478856797519341e-11 5.865109312601124e-11 2.2490268792681e-11 8773/55763/5563/71/7531/51807/10971/347688/7533/2810/53632/10381/60412/5898/7846/51552/23433/5879/51422/4644/7534/6810/5872/4641/10376/11336/6844/9882/79058/801/4218/805/84617/7532/57186/10382/7277/5571/208/5867/4012/10383/60/84790/5564/5565/7280/7529/55770/23265/6517/10890/10640/4627/207/8766/149371/9847/808/54536/6814 61 Human_herpesvirus_2 R-HSA-6798695 Neutrophil degranulation 293/4920 480/10654 1.6185795631716994e-11 8.24004141251047e-11 3.1597151281055185e-11 5869/8773/9798/1727/5689/8804/5777/5806/4893/9218/4790/3240/960/1511/5657/57826/1915/3107/203068/5175/5199/383/654364/8836/2268/5211/5908/1460/29108/6280/5788/535/10577/10312/5709/10576/1509/5695/2896/8655/567/7133/3106/3074/3417/3043/388698/1667/2548/1432/3920/5476/5683/201294/2588/3482/80142/2444/5702/566/9961/51552/10075/56729/10487/684/6709/6093/8826/9522/4282/3608/2720/3312/387263/2665/4758/1654/2519/6037/5879/51316/2717/5718/1992/3303/58485/2934/56954/161/56888/3579/5707/2358/3848/823/5594/4831/5787/6727/7414/10533/4257/2517/25852/3934/5834/1315/102/4069/965/4973/9861/5870/410/411/226/2821/978/55832/5713/2495/3728/3614/4125/5478/5719/5328/728/5580/23191/3685/302/1729/6036/64114/2040/230/317/23250/2990/5663/7879/8907/671/28956/30/10450/25801/23352/7276/5284/83858/4332/10159/1938/8635/1650/3684/79888/387921/3163/54472/3577/55860/1378/2760/5864/4318/3958/79980/23317/5836/6993/11240/5329/966/5611/1116/527/6279/6515/4048/353/6286/210/10092/5795/6793/197/140885/2171/3310/1832/5708/55313/23218/820/51143/4860/6386/10788/6402/5473/3326/10857/55004/10097/3916/10383/387/196527/79930/5049/51806/80184/3304/2547/8673/10493/1075/6282/114790/22931/1778/10694/2512/3837/10890/5036/8621/5005/327/11333/5315/8876/23197/1991/10120/6317/7520/5717/2919/221/9725/1604/2357/10213/6278/2799/5768/1471/9588/29952/7415/3146/4353/5701/6836/8649/5265/3320/5686/388697/23593/1669/175/5873/5878/2683/8566/11031/22875/5646/948/1675/719/93100/47/5906/89777/81567/3687/7097/5660/2212/10970/3689/2207/5724/51382/2950/718 293 Human_herpesvirus_2 R-HSA-2871796 FCERI mediated MAPK activation 32/4920 32/10654 1.7331634332656512e-11 8.759670781848056e-11 3.358971502813916e-11 3725/4893/5335/2885/3845/3265/5062/5879/5601/5336/5594/4214/7410/7409/2353/6464/2205/3937/10451/2206/6850/4067/5602/6654/5058/6416/5595/9402/27040/5609/5599/2207 32 Human_herpesvirus_2 R-HSA-5673000 RAF activation 32/4920 32/10654 1.7331634332656512e-11 8.759670781848056e-11 3.358971502813916e-11 4893/5526/817/5605/3717/4296/5894/5518/4140/3845/3265/5515/818/8844/5528/6714/5519/369/801/805/673/8315/5529/816/7529/5516/815/5604/5525/5527/808/5245 32 Human_herpesvirus_2 R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 39/4920 41/10654 1.8863975777330034e-11 9.39842209546692e-11 3.6039062170587435e-11 23165/348995/57122/23511/81608/23279/23225/9972/8021/55746/53981/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10898/10482/51692/8086/22916/81929/9631/29894/79023/23636/4686/8189/53371/9688/10189/8480/55339 39 Human_herpesvirus_2 R-HSA-74158 RNA Polymerase III Transcription 39/4920 41/10654 1.8863975777330034e-11 9.39842209546692e-11 3.6039062170587435e-11 55718/2976/4774/5435/9328/84265/55290/10302/9330/2972/2975/10622/7702/661/55814/11128/9533/5434/2971/10623/112495/9329/6621/6908/6619/51728/171568/10621/4784/6618/5440/5451/6617/5441/51082/55703/27297/5437/6741 39 Human_herpesvirus_2 R-HSA-749476 RNA Polymerase III Abortive And Retractive Initiation 39/4920 41/10654 1.8863975777330034e-11 9.39842209546692e-11 3.6039062170587435e-11 55718/2976/4774/5435/9328/84265/55290/10302/9330/2972/2975/10622/7702/661/55814/11128/9533/5434/2971/10623/112495/9329/6621/6908/6619/51728/171568/10621/4784/6618/5440/5451/6617/5441/51082/55703/27297/5437/6741 39 Human_herpesvirus_2 R-HSA-8853659 RET signaling 39/4920 41/10654 1.8863975777330034e-11 9.39842209546692e-11 3.6039062170587435e-11 5295/2674/1796/5335/5291/5578/55816/2668/2885/8660/9846/5623/5290/5567/4902/6714/5598/64096/220164/9260/55715/5781/6464/5568/2675/2676/5566/8503/2886/6654/5293/2549/10818/53358/5979/9048/5296/2887/9046 39 Human_herpesvirus_2 R-HSA-5358346 Hedgehog ligand biogenesis 56/4920 65/10654 1.9934485864690494e-11 9.8965532661584e-11 3.794918921609612e-11 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/6868/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/9861/5698/5692/5713/5710/5719/6233/5706/84447/5714/5688/5687/5708/5704/7311/147111/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721/5034 56 Human_herpesvirus_2 R-HSA-109704 PI3K Cascade 41/4920 44/10654 3.546866384523828e-11 1.7301787241579647e-10 6.634519919703473e-11 5295/2250/5291/9965/2264/2885/8660/9846/2252/2253/2323/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/2246/2251/5781/30849/5170/2322/2263/208/2549/8822/8817/2254/152831/5289/26281/10818/2261/2255/27006/5296 41 Human_herpesvirus_2 R-HSA-451927 Interleukin-2 family signaling 41/4920 44/10654 3.546866384523828e-11 1.7301787241579647e-10 6.634519919703473e-11 5295/5777/1437/5291/6776/3558/3717/3563/2885/9846/3600/5290/1439/50615/3718/3567/3932/6777/59067/3562/6464/6775/1438/3581/6774/6850/6772/8503/3636/6654/3716/5293/2185/6655/3561/3578/3568/3560/5296/3559/3601 41 Human_herpesvirus_2 R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 41/4920 44/10654 3.546866384523828e-11 1.7301787241579647e-10 6.634519919703473e-11 834/79370/55367/472/1387/51499/7159/637/27166/23368/332/64065/8797/7157/604/63970/839/317/5875/55240/5366/84883/147923/843/94241/8626/7161/10397/8795/665/27113/9540/8793/835/58484/3486/355/8794/124446/5876/581 41 Human_herpesvirus_2 R-HSA-69231 Cyclin D associated events in G1 41/4920 44/10654 3.546866384523828e-11 1.7301787241579647e-10 6.634519919703473e-11 8454/5925/1869/5753/1031/3717/5520/28227/1030/5518/7314/5515/25/7027/5934/6714/5519/6502/595/896/6233/1163/1019/1029/4331/4067/1874/7311/5516/894/902/1027/6500/7316/1875/1026/5933/1871/1021/1022/1028 41 Human_herpesvirus_2 R-HSA-69236 G1 Phase 41/4920 44/10654 3.546866384523828e-11 1.7301787241579647e-10 6.634519919703473e-11 8454/5925/1869/5753/1031/3717/5520/28227/1030/5518/7314/5515/25/7027/5934/6714/5519/6502/595/896/6233/1163/1019/1029/4331/4067/1874/7311/5516/894/902/1027/6500/7316/1875/1026/5933/1871/1021/1022/1028 41 Human_herpesvirus_2 R-HSA-182971 EGFR downregulation 31/4920 31/10654 3.765881601877878e-11 1.8180118078031136e-10 6.971323473530736e-11 374/7039/6456/30011/2885/8874/10252/7314/1839/8027/2060/2069/9146/6455/6233/29924/255324/5782/5796/998/7311/1956/10253/685/58513/7316/1950/867/5774/10254/6457 31 Human_herpesvirus_2 R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 31/4920 31/10654 3.765881601877878e-11 1.8180118078031136e-10 6.971323473530736e-11 3725/9252/1848/1432/6196/5518/1386/6197/51231/5515/5601/1849/5594/5528/9261/5519/5598/4208/6195/2353/5600/1846/5602/5595/5516/1845/4205/466/2002/1385/5599 31 Human_herpesvirus_2 R-HSA-5654733 Negative regulation of FGFR4 signaling 31/4920 31/10654 3.765881601877878e-11 1.8180118078031136e-10 6.971323473530736e-11 8569/9965/2264/2885/5518/2253/7314/5515/8823/5594/8074/2249/6714/2247/6233/2246/2251/5781/673/7311/5595/5516/8822/10253/8817/2254/7316/152831/26281/10818/867 31 Human_herpesvirus_2 R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 46/4920 51/10654 3.893938927412243e-11 1.8660895679891873e-10 7.155681802063801e-11 5689/5682/143471/5705/5709/5695/5711/4946/5683/5699/5702/5696/5691/5718/1728/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/5706/5714/5688/5687/5708/5704/5694/5684/5720/5690/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 46 Human_herpesvirus_2 R-HSA-3928665 EPH-ephrin mediated repulsion of cells 46/4920 51/10654 3.893938927412243e-11 1.8660895679891873e-10 7.155681802063801e-11 71/2042/1947/1212/2051/2045/2050/285220/2047/2534/1948/163/284656/1759/5879/161/2046/4313/2041/102/6714/1943/2043/7525/1942/7410/1213/1211/1175/5663/1173/7074/1949/1945/10451/4318/160/2049/8218/4067/2044/2048/60/1946/1944/1969 46 Human_herpesvirus_2 R-HSA-5675221 Negative regulation of MAPK pathway 38/4920 40/10654 3.9054588815773704e-11 1.8660895679891873e-10 7.155681802063801e-11 4893/1844/1850/1848/5526/1852/5605/5037/5894/1847/5518/4140/3845/3265/7314/5515/8844/1849/5594/5528/5519/6233/1843/369/1846/11221/673/8315/5529/7311/5536/7529/5595/5516/5604/5525/7316/5527 38 Human_herpesvirus_2 R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 90/4920 119/10654 4.57741587570866e-11 2.1797218455755522e-10 8.35833188904911e-11 84498/79718/9441/892/1543/5469/9612/1387/2101/84246/4801/2274/55588/10499/23054/85441/9282/23097/10062/7296/51129/57761/5465/2222/10025/6667/23309/336/3156/6604/9439/4199/123/2168/183/116519/9412/9969/405/133522/54797/55090/4899/1374/9440/6721/51/9862/23179/9442/406/19/335/4800/1024/9968/10001/23389/9443/9477/25942/51586/400569/6095/6822/80306/8841/5468/29079/4802/90390/6720/6837/9611/2874/81857/2033/9967/6256/51003/7376/10498/948/112950/196/4520/8202/8648/10891/219541 90 Human_herpesvirus_2 R-HSA-8848021 Signaling by PTK6 48/4920 54/10654 4.961296516712387e-11 2.346559163309913e-10 8.998084009684626e-11 4893/1796/5770/2909/9021/27043/3091/2064/5753/145957/9542/9564/3845/3265/5829/7314/5879/120892/1839/2065/2069/898/5921/6421/595/6233/1019/10657/6774/2908/3084/10718/7311/2034/387/1956/63916/1017/685/207/55620/1027/10457/7316/1950/867/2066/1398 48 Human_herpesvirus_2 R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 48/4920 54/10654 4.961296516712387e-11 2.346559163309913e-10 8.998084009684626e-11 4893/1796/5770/2909/9021/27043/3091/2064/5753/145957/9542/9564/3845/3265/5829/7314/5879/120892/1839/2065/2069/898/5921/6421/595/6233/1019/10657/6774/2908/3084/10718/7311/2034/387/1956/63916/1017/685/207/55620/1027/10457/7316/1950/867/2066/1398 48 Human_herpesvirus_2 R-HSA-4570464 SUMOylation of RNA binding proteins 43/4920 47/10654 5.552287618042162e-11 2.617239954632669e-10 1.0036032908741813e-10 1912/23165/6045/80012/348995/6613/57122/23511/3190/1911/23279/23225/57332/9972/8021/55746/51602/10762/79902/9883/84733/6396/129401/7703/6015/4928/5903/55706/7175/8535/4927/8086/7329/648/81929/9631/79023/23636/3183/53371/9688/7341/8480 43 Human_herpesvirus_2 R-HSA-447115 Interleukin-12 family signaling 50/4920 57/10654 5.878932594581235e-11 2.7619146417495736e-10 1.0590800505957011e-10 3593/5908/3313/6175/3936/5898/3717/3181/4001/3594/4282/5062/3572/10148/1072/3592/6627/9049/27250/9987/3185/149233/3458/5478/302/552900/51561/7297/6775/3595/821/4478/6774/6772/998/6648/3716/2939/6888/246778/3586/829/6647/6950/9466/4507/6845/375/5721/5034 50 Human_herpesvirus_2 R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 40/4920 43/10654 7.197351030893572e-11 3.3699971382110374e-10 1.2922545417200218e-10 2788/107/554/2782/2787/22841/5567/10681/112/5573/111/2792/2785/2783/2784/196883/115/2791/5568/359/113/5566/2786/5577/109/54331/5575/59345/51764/94235/114/108/8766/55970/2778/2793/5576/4645/551/2790 40 Human_herpesvirus_2 R-HSA-5628897 TP53 Regulates Metabolic Genes 69/4920 86/10654 7.987746769089156e-11 3.727615158908273e-10 1.42938626394227e-10 5563/7531/10971/9997/27327/7295/7533/2810/53632/7001/10325/192669/2475/10670/4513/4343/64121/7296/51422/7249/27244/7534/1351/2821/10000/2877/54541/7157/50484/26523/2744/57521/28956/83667/389541/7532/1345/58528/64223/5571/10128/25824/6009/8626/208/55004/5562/1340/4697/5564/5565/7248/7529/27161/27165/207/57690/192670/153129/2539/54205/143686/8649/5728/23112/10542/1349/1327/5052 69 Human_herpesvirus_2 R-HSA-5654696 Downstream signaling of activated FGFR2 30/4920 30/10654 8.1817435865748e-11 3.805462133290605e-10 1.4592373593821117e-10 5295/4893/2250/5335/2885/2252/2253/3845/3265/5290/8823/8074/2249/2248/2247/2246/2251/5781/6464/2263/6654/2549/8822/8817/10817/2254/26281/10818/2255/27006 30 Human_herpesvirus_2 R-HSA-1989781 PPARA activates gene expression 88/4920 117/10654 1.2519019260104664e-10 5.803518862300175e-10 2.225409488551195e-10 84498/79718/9441/892/1543/5469/9612/1387/2101/84246/4801/2274/55588/10499/23054/85441/9282/23097/10062/7296/51129/57761/5465/2222/10025/6667/336/3156/6604/9439/4199/123/2168/183/116519/9412/9969/405/133522/54797/55090/4899/1374/9440/6721/51/9862/23179/9442/406/19/335/4800/1024/9968/10001/23389/9443/9477/51586/400569/6095/6822/80306/8841/5468/29079/4802/90390/6720/6837/9611/2874/81857/2033/9967/6256/51003/7376/10498/948/112950/196/4520/8202/8648/10891/219541 88 Human_herpesvirus_2 R-HSA-5358351 Signaling by Hedgehog 107/4920 149/10654 1.557297372819426e-10 7.195433405766325e-10 2.759151155594606e-10 8454/5689/5682/22873/1452/51684/143471/10381/5705/8452/5709/9978/5695/107/5711/7846/5683/408/5699/6400/5702/83737/6868/6469/5696/5691/7314/5718/8945/5700/122706/5707/5567/10956/23198/112/5573/2737/5727/8650/111/9861/2932/5698/5692/5713/10376/5710/5719/6233/23322/196883/115/84617/54903/10382/23288/79809/5568/409/79577/7277/5706/113/84447/5714/5566/5688/5687/5708/5577/5704/7311/147111/10383/84790/5694/7280/109/57154/5684/5720/2735/5575/5690/5717/9491/6500/114/7289/10197/108/64750/7316/10213/2778/7415/5715/5701/5576/5685/5686/5716/8481/5693/5721/5034 107 Human_herpesvirus_2 R-HSA-3232142 SUMOylation of ubiquitinylation proteins 36/4920 38/10654 1.6671781257202271e-10 7.652620904945305e-10 2.9344636552797785e-10 23165/348995/57122/23511/23279/23225/7428/5371/9972/8021/55746/51588/10762/79902/9883/9063/6396/129401/8554/4928/5903/55706/7175/4927/8086/7329/81929/9631/79023/23636/53371/9688/7341/5987/8480/4193 36 Human_herpesvirus_2 R-HSA-420499 Class C/3 (Metabotropic glutamate/pheromone receptors) 36/4920 38/10654 1.6671781257202271e-10 7.652620904945305e-10 2.9344636552797785e-10 50833/5726/2550/50832/259294/2912/259295/9568/2911/2914/259296/259289/50835/338398/2916/259293/54429/80835/50840/2913/2918/50838/83756/259286/259287/50836/846/259290/80834/259292/50834/259285/2917/50831/50839/50837 36 Human_herpesvirus_2 R-HSA-186763 Downstream signal transduction 29/4920 29/10654 1.777367115259803e-10 8.105257203139168e-10 3.1080309575947183e-10 5295/4893/5335/5291/6776/2885/8440/9564/3845/3265/1399/5290/5921/6778/6714/5154/6777/5781/6774/6772/2889/5159/2886/6654/4690/1398/5155/5296/5156 29 Human_herpesvirus_2 R-HSA-5654732 Negative regulation of FGFR3 signaling 29/4920 29/10654 1.777367115259803e-10 8.105257203139168e-10 3.1080309575947183e-10 2250/8569/2885/5518/2253/7314/5515/8823/5594/8074/2249/6714/2247/6233/2246/5781/673/7311/5595/5516/8822/10253/8817/2254/7316/26281/10818/2261/867 29 Human_herpesvirus_2 R-HSA-5617833 Cilium Assembly 137/4920 201/10654 1.8190899049725786e-10 8.268590477148085e-10 3.170662513793626e-10 55763/79738/79867/7531/11190/203068/54801/51807/85302/347688/79441/10381/5116/5048/10576/22832/60412/192668/8655/83658/89891/9702/132320/7846/7840/11064/84902/2847/5518/55835/23332/93323/10575/1454/10013/54806/91147/983/79959/5310/8729/10376/10540/11336/117177/57545/26005/54930/54820/23322/378/56623/1453/9793/4218/140735/6102/84617/11258/22981/8636/54903/80776/3842/7532/55125/10382/6753/79809/121441/7277/55112/26146/9814/23354/146057/9738/1639/55722/4957/5566/7283/22919/27077/22994/4867/1069/5577/10383/5347/403/84790/22948/80184/22897/5108/261734/57787/7280/10806/9657/1778/55770/23265/115106/10694/22995/55559/10142/10640/51134/95681/79989/7203/1781/80321/8766/79598/149371/10121/347240/84131/6950/55212/3320/79600/10733/4751/80254/200894/26123/54536/9662/55142/8481/51259/55755 137 Human_herpesvirus_2 R-HSA-9022692 Regulation of MECP2 expression and activity 32/4920 33/10654 3.16724114132176e-10 1.4310426216323435e-9 5.487456669417255e-10 2290/79718/817/9212/27327/28996/9612/192669/4204/4343/814/818/3066/26523/801/805/3930/5566/816/25942/27161/815/8841/57690/192670/9611/2874/3064/3065/23112/1385/808 32 Human_herpesvirus_2 R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 63/4920 78/10654 3.1687372336144745e-10 1.4310426216323435e-9 5.487456669417255e-10 3443/4790/7321/9140/9474/4792/177/3093/1387/64135/83737/1540/3551/7314/3445/8737/29110/4214/9636/841/8517/3444/7323/5970/23586/7128/3451/3448/3661/3439/51191/6233/55593/8772/3452/4791/3446/3665/351/54476/7706/843/3440/9246/7189/7311/5094/3456/1147/3441/7186/57506/3449/84166/7316/4793/3146/7322/2033/6288/54941/6285/5300 63 Human_herpesvirus_2 R-HSA-5685938 HDR through Single Strand Annealing (SSA) 35/4920 37/10654 3.4371329264871196e-10 1.5423032362442202e-9 5.914095116425205e-10 83990/9156/1763/7486/5982/472/4683/84126/2067/672/6117/83695/6118/25/5888/116028/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/5983/5883/10111/545/2072/5932/7156 35 Human_herpesvirus_2 R-HSA-6806003 Regulation of TP53 Expression and Degradation 35/4920 37/10654 3.4371329264871196e-10 1.5423032362442202e-9 5.914095116425205e-10 11200/472/639/4194/8900/2475/5518/51230/7314/5515/117584/890/983/5519/10000/900/7157/6233/7874/253260/5170/1029/80196/64223/1616/208/79109/7311/5516/1017/207/7316/9099/5527/4193 35 Human_herpesvirus_2 R-HSA-76061 RNA Polymerase III Transcription Initiation From Type 1 Promoter 28/4920 28/10654 3.8606506473325383e-010 1.7213092058170553e-9 6.600508984712016e-10 55718/2976/5435/9328/84265/9330/2972/2975/10622/661/55814/11128/9533/5434/2971/10623/112495/9329/6908/51728/171568/10621/5440/5441/51082/55703/27297/5437 28 Human_herpesvirus_2 R-HSA-76071 RNA Polymerase III Transcription Initiation From Type 3 Promoter 28/4920 28/10654 3.8606506473325383e-010 1.7213092058170553e-9 6.600508984712016e-10 55718/5435/84265/55290/10302/10622/7702/661/55814/11128/9533/5434/10623/6621/6908/6619/51728/171568/10621/6618/5440/5451/6617/5441/51082/55703/27297/5437 28 Human_herpesvirus_2 R-HSA-448424 Interleukin-17 signaling 59/4920 72/10654 3.881163574589174e-10 1.7249615887062997e-9 6.614514362708367e-10 8454/3605/3725/9252/4790/1848/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/5601/5606/1849/5594/23118/8517/5528/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/1846/79155/7867/5602/7189/112744/7311/6416/5595/5516/1147/1845/6885/5604/6500/7316/4205/466/23291/2002/5609/1385/5599 59 Human_herpesvirus_2 R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 40/4920 44/10654 4.370219749459103e-10 1.9361733067223874e-9 7.424423958108403e-10 892/7321/8239/9612/4609/4089/22938/23327/4088/1030/904/7314/5054/7027/6497/51592/7323/6667/4092/7050/5494/6233/1025/4221/3726/1024/60436/8812/1874/142/905/4087/7311/64750/7316/1875/9611/5933/3065/6498 40 Human_herpesvirus_2 R-HSA-397795 G-protein beta:gamma signalling 31/4920 32/10654 6.678014482885741e-10 2.949280844176668e-9 1.1309272410000755e-9 2788/5331/2782/2787/10681/2792/146850/10000/5294/2785/2783/2784/2791/5170/23236/998/695/2786/208/387/5058/54331/59345/207/9459/51764/94235/55970/2793/23533/2790 31 Human_herpesvirus_2 R-HSA-177243 Interactions of Rev with host cellular proteins 34/4920 36/10654 7.075251512358281e-10 3.1051260555804367e-9 1.1906874348466335e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/5902/7514/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/1104/5905/3837/81929/9631/79023/23636/53371/9688/8480 34 Human_herpesvirus_2 R-HSA-6804757 Regulation of TP53 Degradation 34/4920 36/10654 7.075251512358281e-10 3.1051260555804367e-9 1.1906874348466335e-9 11200/472/4194/8900/2475/5518/51230/7314/5515/117584/890/983/5519/10000/900/7157/6233/7874/253260/5170/1029/80196/64223/1616/208/79109/7311/5516/1017/207/7316/9099/5527/4193 34 Human_herpesvirus_2 R-HSA-109606 Intrinsic Pathway for Apoptosis 46/4920 53/10654 7.759605256924028e-10 3.3948272999042624e-9 1.3017758819181757e-9 7531/55075/10971/7533/2810/1869/8655/836/90427/840/7159/637/578/23368/7027/5594/841/7534/4836/598/10000/708/7157/331/317/140735/1029/572/7532/6774/5366/8626/208/7161/7529/5595/5533/27113/596/10018/842/207/54205/5534/581/5599 46 Human_herpesvirus_2 R-HSA-5654716 Downstream signaling of activated FGFR4 27/4920 27/10654 8.384862953035509e-10 3.645592588276308e-9 1.3979340000157272e-9 5295/4893/5335/9965/2264/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/2251/5781/6464/6654/2549/8822/8817/10817/2254/152831/26281/10818 27 Human_herpesvirus_2 R-HSA-76066 RNA Polymerase III Transcription Initiation From Type 2 Promoter 27/4920 27/10654 8.384862953035509e-10 3.645592588276308e-9 1.3979340000157272e-9 55718/2976/5435/9328/84265/9330/2972/2975/10622/661/55814/11128/9533/5434/10623/112495/9329/6908/51728/171568/10621/5440/5441/51082/55703/27297/5437 27 Human_herpesvirus_2 R-HSA-6806834 Signaling by MET 63/4920 79/10654 8.598652381086614e-10 3.7269700722976034e-9 1.4291388999035923e-9 5295/3675/4893/5770/3249/5908/3082/3688/3910/6456/30011/2885/3845/3265/1399/7314/5879/3918/5290/8027/2060/284217/9101/6714/9146/6455/2335/64759/84951/6233/57610/5781/6464/85440/5747/382/1277/3912/6774/4233/5795/2889/5771/3913/6654/5867/7311/2549/26018/10048/7316/3915/1281/3673/867/3914/200958/1398/5906/23163/1278/10254/6457 63 Human_herpesvirus_2 R-HSA-1433557 Signaling by SCF-KIT 39/4920 43/10654 8.655668842615952e-10 3.740103820883436e-9 1.4341751493613175e-9 5295/5777/4893/5578/6776/3717/2534/2885/9846/3845/3265/5879/5290/3815/9306/6714/7525/7409/3932/6777/5781/10019/2241/4318/6774/6772/8651/8503/4067/1111/2886/6654/9402/867/4254/5296/10076/2887/2242 39 Human_herpesvirus_2 R-HSA-170834 Signaling by TGF-beta Receptor Complex 59/4920 73/10654 1.1128466108377362e-9 4.793800785147171e-9 1.8382243612218476e-9 892/7321/4738/8239/9612/4609/4089/22938/23327/4088/5499/1030/9110/7040/904/7314/5054/7027/6497/51592/50848/7323/6667/4092/11171/7050/5494/9958/9040/6233/7514/1025/57530/5500/4221/5590/3726/5501/1024/60436/8812/1874/142/905/4087/7048/7311/387/57154/10273/64750/7316/1875/9611/5933/867/3065/6498/56288 59 Human_herpesvirus_2 R-HSA-1839124 FGFR1 mutant receptor activation 30/4920 31/10654 1.4065760312748102e-9 6.040510563756854e-9 2.3162860056511247e-9 5295/11052/2250/9530/613/6776/11064/2885/9846/2253/7750/8805/26127/5290/8074/2260/2249/399687/2247/2246/2251/6777/1523/9208/6774/6772/11160/8822/2254/26281 30 Human_herpesvirus_2 R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 33/4920 35/10654 1.4540661255455431e-9 6.225359558910583e-9 2.3871679511612006e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/7884/4927/10482/8086/22916/81929/9631/79023/23636/4686/53371/9688/10189/8480 33 Human_herpesvirus_2 R-HSA-2980766 Nuclear Envelope Breakdown 45/4920 52/10654 1.4690897407748919e-9 6.270504991112344e-9 2.4044793574942065e-9 23165/5579/91754/5578/348995/57122/23511/23279/23225/9663/4001/9972/8021/55746/10762/983/79902/9883/7444/2010/64900/23175/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/5347/7112/4000/81929/9631/79023/23636/7443/53371/9688/8815/23592/8480 45 Human_herpesvirus_2 R-HSA-74752 Signaling by Insulin receptor 62/4920 78/10654 1.4989812285007188e-9 6.378643525534974e-9 2.445946013551005e-9 5295/3643/4893/2250/5291/535/50617/10312/9965/2264/3630/2885/8660/9846/2252/2253/3845/3265/2323/54106/51606/5290/3667/8823/9550/9114/5594/8074/57761/2260/2249/2248/2247/2246/2251/528/5781/30849/5170/6464/2322/527/2263/208/6654/2549/5595/8822/8817/2254/152831/5289/26281/10818/23545/2261/245972/2255/27006/5296/51382/2887 62 Human_herpesvirus_2 R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 67/4920 86/10654 1.580756032904655e-9 6.706237715353081e-9 2.5715648382180985e-9 5295/5335/71/51517/5291/2268/10094/2534/8976/2885/5879/25/1072/5290/10093/10006/5336/4771/5594/4644/4641/6714/10810/7525/7410/5580/7409/23191/10109/2214/5747/2209/10451/6850/10092/4650/10163/4067/55845/998/695/3326/10097/60/5058/63916/5595/23646/4690/4627/10458/3708/919/3055/10552/10768/4620/917/3320/1398/10096/7454/5296/5581/5338/10095/2212 67 Human_herpesvirus_2 R-HSA-3899300 SUMOylation of transcription cofactors 40/4920 45/10654 2.1719139429812296e-9 9.186342961249914e-9 3.5225826392762825e-9 1912/6045/80012/6613/28996/9612/1911/1387/57332/4152/115426/10499/6612/11315/3622/51588/1655/84733/10155/9063/7690/7703/6015/8554/8535/4869/10210/10521/1616/7329/25942/648/1487/8204/7341/10401/2033/6294/8648/10891 40 Human_herpesvirus_2 R-HSA-114452 Activation of BH3-only proteins 29/4920 30/10654 2.9593957056727478e-9 1.2356543903261464e-8 4.738223602002516e-9 7531/10971/7533/2810/1869/8655/90427/7159/637/23368/7027/7534/10000/7157/140735/572/7532/5366/8626/208/7161/7529/5533/27113/596/10018/207/5534/5599 29 Human_herpesvirus_2 R-HSA-3928663 EPHA-mediated growth cone collapse 29/4920 30/10654 2.9593957056727478e-9 1.2356543903261464e-8 4.738223602002516e-9 2042/2045/285220/79784/2534/9475/4628/6093/284656/2046/2041/6714/1943/2043/7525/1942/10627/1945/4067/2044/387/4629/4627/10398/4637/1946/103910/1944/1969 29 Human_herpesvirus_2 R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 29/4920 30/10654 2.9593957056727478e-9 1.2356543903261464e-8 4.738223602002516e-9 4893/817/1741/1739/6196/1740/6197/3845/3265/5923/818/5594/2902/6195/2906/801/4747/805/5170/2904/27330/816/5924/5595/815/1742/88/1385/808 29 Human_herpesvirus_2 R-HSA-159227 Transport of the SLBP independent Mature mRNA 32/4920 34/10654 2.9832227423588393e-9 1.2356543903261464e-8 4.738223602002516e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10482/8086/22916/81929/9631/79023/23636/4686/53371/9688/10189/8480 32 Human_herpesvirus_2 R-HSA-165054 Rev-mediated nuclear export of HIV RNA 32/4920 34/10654 2.9832227423588393e-9 1.2356543903261464e-8 4.738223602002516e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/5902/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/1104/5905/81929/9631/79023/23636/53371/9688/8480 32 Human_herpesvirus_2 R-HSA-187687 Signalling to ERKs 32/4920 34/10654 2.9832227423588393e-9 1.2356543903261464e-8 4.738223602002516e-9 4893/5605/5898/1432/5603/2885/3845/3265/1399/5899/5594/9261/6714/4914/5600/6300/6464/673/7867/2889/6654/5900/7529/5595/25759/5604/57498/10818/53358/4803/1398/5906 32 Human_herpesvirus_2 R-HSA-4085377 SUMOylation of SUMOylation proteins 32/4920 34/10654 2.9832227423588393e-9 1.2356543903261464e-8 4.738223602002516e-9 23165/348995/6613/57122/23511/23279/23225/9972/8021/55746/51588/10762/79902/9883/6396/129401/4928/5903/55706/7175/10210/4927/8086/7329/81929/9631/79023/23636/53371/9688/7341/8480 32 Human_herpesvirus_2 R-HSA-1643713 Signaling by EGFR in Cancer 25/4920 25/10654 3.95387795987087e-9 1.6044722155997733e-8 6.152487443277325e-9 5295/374/4893/5335/7039/2885/3845/3265/7314/1839/5290/2069/6233/255324/6464/6654/7311/1956/2549/11140/685/7316/1950/867/3320 25 Human_herpesvirus_2 R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 25/4920 25/10654 3.95387795987087e-9 1.6044722155997733e-8 6.152487443277325e-9 11065/7321/8697/51529/29945/51434/9184/29882/7314/996/51433/119504/7324/64682/6233/246184/8881/10393/7311/25906/991/7316/4085/4751/701 25 Human_herpesvirus_2 R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 25/4920 25/10654 3.95387795987087e-9 1.6044722155997733e-8 6.152487443277325e-9 9252/1848/1432/6196/5518/6197/51231/5515/1849/5594/5528/9261/5519/5598/4208/6195/5600/1846/5595/5516/1845/4205/466/2002/1385 25 Human_herpesvirus_2 R-HSA-392451 G beta:gamma signalling through PI3Kgamma 25/4920 25/10654 3.95387795987087e-9 1.6044722155997733e-8 6.152487443277325e-9 2788/2782/2787/10681/2792/146850/10000/5294/2785/2783/2784/2791/5170/2786/208/387/54331/59345/207/51764/94235/55970/2793/23533/2790 25 Human_herpesvirus_2 R-HSA-5654700 FRS-mediated FGFR2 signaling 25/4920 25/10654 3.95387795987087e-9 1.6044722155997733e-8 6.152487443277325e-9 4893/2250/2885/2252/2253/3845/3265/8823/8074/2249/2248/2247/2246/2251/5781/2263/6654/8822/8817/10817/2254/26281/10818/2255/27006 25 Human_herpesvirus_2 R-HSA-5654708 Downstream signaling of activated FGFR3 25/4920 25/10654 3.95387795987087e-9 1.6044722155997733e-8 6.152487443277325e-9 5295/4893/2250/5335/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/5781/6464/6654/2549/8822/8817/10817/2254/26281/10818/2261 25 Human_herpesvirus_2 R-HSA-9006335 Signaling by Erythropoietin 25/4920 25/10654 3.95387795987087e-9 1.6044722155997733e-8 6.152487443277325e-9 5295/4893/5335/5291/6776/3717/2885/2056/8660/3845/3265/1399/5290/5336/5294/2057/7409/6777/6464/2889/4067/6654/5293/2549/23533 25 Human_herpesvirus_2 R-HSA-6790901 rRNA modification in the nucleus and cytosol 51/4920 62/10654 4.761256854486208e-9 1.926520114531992e-8 7.387407957979817e-9 55226/10528/84135/27340/88745/51096/55272/51077/23160/10607/11103/6208/22984/10813/9136/6203/27292/56902/51602/9724/54555/10171/5822/2091/55651/55127/8602/6194/10436/9277/84128/4839/134430/92856/65083/11056/9790/55505/51202/57647/6187/79050/55813/25879/57050/1736/10199/25926/27341/6201/10885 51 Human_herpesvirus_2 R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 41/4920 47/10654 4.835195200516044e-9 1.9396198512098743e-8 7.437640030955157e-9 8454/79718/892/3091/9978/9759/9612/4609/22938/1387/9794/388585/7314/79885/2648/9734/51564/55534/3280/84441/10013/7091/8850/3066/6233/10046/1024/10014/26508/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 41 Human_herpesvirus_2 R-HSA-73762 RNA Polymerase I Transcription Initiation 41/4920 47/10654 4.835195200516044e-9 1.9396198512098743e-8 7.437640030955157e-9 2074/9112/5435/5928/2965/1107/2967/2648/30834/404672/8850/57459/2068/3066/9533/5434/9015/9219/5931/4331/9013/1108/2966/54815/2071/10849/57504/6908/53615/5440/902/9014/25885/5441/51082/7343/5437/3065/2968/1022/10919 41 Human_herpesvirus_2 R-HSA-9020591 Interleukin-12 signaling 41/4920 47/10654 4.835195200516044e-9 1.9396198512098743e-8 7.437640030955157e-9 3593/5908/3313/6175/3936/5898/3717/3181/4001/3594/4282/5062/1072/3592/6627/9049/27250/9987/3185/3458/5478/302/552900/7297/6775/3595/4478/998/6648/3716/2939/6888/3586/829/6647/6950/4507/6845/375/5721/5034 41 Human_herpesvirus_2 R-HSA-191859 snRNP Assembly 45/4920 53/10654 5.36794157561394e-9 2.141059317908694e-8 8.21007708371003e-9 23165/6633/6606/25929/348995/57122/23511/23279/23225/79084/9972/8021/55746/10762/79902/9883/6636/10419/6396/129401/50628/4928/6635/5903/6632/55706/7175/6637/4927/51808/8086/79833/22916/81929/11218/9631/79023/23636/4686/53371/9688/1207/6634/8480/6628 45 Human_herpesvirus_2 R-HSA-194441 Metabolism of non-coding RNA 45/4920 53/10654 5.36794157561394e-9 2.141059317908694e-8 8.21007708371003e-9 23165/6633/6606/25929/348995/57122/23511/23279/23225/79084/9972/8021/55746/10762/79902/9883/6636/10419/6396/129401/50628/4928/6635/5903/6632/55706/7175/6637/4927/51808/8086/79833/22916/81929/11218/9631/79023/23636/4686/53371/9688/1207/6634/8480/6628 45 Human_herpesvirus_2 R-HSA-163359 Glucagon signaling in metabolic regulation 31/4920 33/10654 6.109500127712808e-9 2.409380332055755e-8 9.23897721314613e-9 2788/107/2782/2787/5567/112/5573/111/2785/2783/2784/196883/115/2791/5568/113/5566/2786/5577/109/54331/5575/59345/51764/94235/114/108/55970/2778/5576/2790 31 Human_herpesvirus_2 R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 31/4920 33/10654 6.109500127712808e-9 2.409380332055755e-8 9.23897721314613e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/3303/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/3304/81929/9631/79023/23636/53371/9688/8480 31 Human_herpesvirus_2 R-HSA-180746 Nuclear import of Rev protein 31/4920 33/10654 6.109500127712808e-9 2.409380332055755e-8 9.23897721314613e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/1104/3837/81929/9631/79023/23636/53371/9688/8480 31 Human_herpesvirus_2 R-HSA-5654726 Negative regulation of FGFR1 signaling 31/4920 33/10654 6.109500127712808e-9 2.409380332055755e-8 9.23897721314613e-9 2250/8569/2885/5518/2253/7314/5515/5594/8074/2260/2249/6714/2248/2247/6233/2246/2251/5781/673/7311/5595/5516/8822/10253/2254/7316/26281/10818/867/2255/27006 31 Human_herpesvirus_2 R-HSA-72086 mRNA Capping 28/4920 29/10654 6.219258954536865e-9 2.438925080210535e-8 9.352269104566713e-9 5431/5435/5433/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/4686/8731/5437/2968/1022 28 Human_herpesvirus_2 R-HSA-8863795 Downregulation of ERBB2 signaling 28/4920 29/10654 6.219258954536865e-9 2.438925080210535e-8 9.352269104566713e-9 26469/2064/145957/4145/9542/7314/1839/2065/2069/9101/10000/6233/5782/10193/3084/208/10718/7311/1956/11140/8065/685/10273/207/7316/1950/3320/2066 28 Human_herpesvirus_2 R-HSA-165159 mTOR signalling 36/4920 40/10654 6.628900130511318e-9 2.585086401870709e-8 9.912737330481665e-9 5563/53632/6198/29904/10325/2475/10670/64121/84335/51422/7249/1981/5494/1977/1978/57521/28956/6194/389541/58528/64223/5571/6794/6009/208/1975/55004/5562/5564/5565/7248/7529/207/153129/8649/10542 36 Human_herpesvirus_2 R-HSA-168276 NS1 Mediated Effects on Host Pathways 36/4920 40/10654 6.628900130511318e-9 2.585086401870709e-8 9.912737330481665e-9 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/402569/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/4927/10898/3840/8086/3837/81929/9631/79023/23636/53371/9688/8480 36 Human_herpesvirus_2 R-HSA-8939211 ESR-mediated signaling 145/4920 223/10654 8.11366365162914e-9 3.153218374591445e-8 1.2091288504072457e-8 5295/2788/374/3725/4893/857/7031/2770/7039/27327/10274/5431/5435/5433/1509/5469/4609/1387/8312/2782/5439/192669/10499/1386/4343/3845/904/3265/8877/2773/2787/6387/1839/5290/4316/5594/2069/10681/5481/5438/4313/865/1655/6667/2792/6714/2099/8850/10000/2785/595/2783/2784/2771/7514/1025/2353/255324/26523/801/2791/2957/805/5170/2963/3838/5434/5590/6464/5241/5747/5436/1903/3315/4318/5885/7033/2962/8503/10524/8243/4602/2786/208/3326/6908/1956/5536/3169/858/5432/3480/10728/5595/7528/3727/27161/2354/596/5440/685/54331/2309/59345/8204/5430/207/5451/2625/57690/1027/51764/94235/5441/10735/192670/2100/1950/55970/4314/346562/2289/7391/2958/5437/2793/3320/2033/4846/9126/3065/2002/2066/861/23028/23112/10498/1385/5296/808/3276/8202/8648/2288/2790 145 Human_herpesvirus_2 R-HSA-5696395 Formation of Incision Complex in GG-NER 38/4920 43/10654 8.13079880876794e-9 3.153218374591445e-8 1.2091288504072457e-8 6613/9978/85015/2965/2067/2967/6612/6117/7334/7314/6118/404672/1643/2068/6233/5886/8451/8554/8450/4331/2966/6119/1642/142/2071/1069/7329/7311/902/7336/2072/7316/7341/10401/2968/5887/1022/7508 38 Human_herpesvirus_2 R-HSA-982772 Growth hormone receptor signaling 24/4920 24/10654 8.584502188199998e-9 3.3199732219558e-8 1.2730724384943293e-8 5777/5770/9021/6776/3717/5618/6868/8660/1154/3667/2690/5594/5617/8835/6777/6774/6772/8651/1442/4067/2689/5595/25970/2688 24 Human_herpesvirus_2 R-HSA-163685 Integration of energy metabolism 79/4920 108/10654 1.0024018041563498e-8 3.866012467820633e-8 1.4824559087131749e-8 2788/5563/5313/5331/2770/5578/107/9495/2782/3630/2776/8826/5518/31/777/2181/6513/5515/2787/5567/51422/10681/112/5573/5528/111/2792/5519/51085/2785/2783/2784/2771/9370/7086/6844/2182/196883/115/2791/9254/5568/150/113/5566/775/32/23236/6794/6514/2786/5577/6888/773/5565/109/5516/54331/5575/59345/776/51764/94235/114/3708/4082/108/55970/2778/2194/2767/10768/152/2793/5576/948/47/5906/2790 79 Human_herpesvirus_2 R-HSA-5632684 Hedgehog 'on' state 65/4920 85/10654 1.0687184586267385e-8 4.1104556101028406e-8 1.576189745227405e-8 5689/5682/22873/1452/51684/143471/5705/8452/5709/9978/5695/5711/5683/408/5699/5702/83737/6469/5696/5691/7314/5718/5700/122706/5707/23198/2737/5727/8650/9861/5698/5692/5713/5710/5719/6233/23288/409/79577/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/2735/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/5716/5693/5721 65 Human_herpesvirus_2 R-HSA-69190 DNA strand elongation 30/4920 32/10654 1.2488194776068573e-8 4.7899925168482197e-8 1.836764047813979e-8 2237/1763/5982/5422/4174/84515/6117/10714/5558/6118/3978/5557/5985/4175/5984/23649/5424/4172/8318/4173/5425/5111/6119/51659/5983/4176/57804/9837/4171/5981 30 Human_herpesvirus_2 R-HSA-69205 G1/S-Specific Transcription 27/4920 28/10654 1.3053859520701595e-8 4.993279598082577e-8 1.9147162368587325e-8 5422/1869/4998/5928/990/8900/6241/7027/898/5934/1876/983/7298/1719/26271/8318/286826/5111/91750/1874/81620/55957/1875/5933/3065/7083/132660 27 Human_herpesvirus_2 R-HSA-8878171 Transcriptional regulation by RUNX1 153/4920 239/10654 1.5434548071798077e-8 5.887838501503353e-8 2.2577425832832404e-8 1912/9070/5689/1437/5579/5682/1459/6045/9021/5929/27327/80012/1460/143471/5705/5709/5695/28996/1457/1911/6603/10413/5711/1387/3558/5683/10138/57332/5699/8312/5702/192669/83737/5371/57492/6688/4343/5696/5691/7314/5718/84661/25/4773/8861/5700/122706/5707/23198/86/100506658/865/7082/23309/6714/2099/9861/8850/84733/5588/6604/8289/5698/5692/5713/6602/595/5710/3458/896/5719/23067/6233/26523/5781/1493/23429/6015/55904/6595/3562/6597/8535/3674/1378/6938/3958/5706/6599/4331/5714/5688/5687/5708/6886/4602/5704/7311/7161/860/58508/25942/648/5694/6601/23466/4297/4004/27161/894/5684/5720/902/2624/11091/640/8085/5690/2625/57690/5717/9491/4005/6598/10197/192670/5196/7316/10213/5079/10398/122809/5715/5701/5685/5686/2033/1021/6605/50943/3065/861/23112/9757/5716/9739/3276/3977/3559/7057/1022/5693/5721 153 Human_herpesvirus_2 R-HSA-168253 Host Interactions with Influenza Factors 37/4920 42/10654 1.566360374868253e-8 5.942830690557057e-8 2.2788298136722547e-8 23165/348995/57122/23511/23279/23225/3836/9972/8021/7040/55746/402569/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/4927/10898/3840/8086/3837/81929/9631/79023/23636/53371/9688/8480 37 Human_herpesvirus_2 R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 37/4920 42/10654 1.566360374868253e-8 5.942830690557057e-8 2.2788298136722547e-8 83990/9156/1763/7486/5982/472/4683/84126/672/6117/83695/6118/5888/116028/7517/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/1111/79728/5983/5883/10111/675/545/10635/5932/7156 37 Human_herpesvirus_2 R-HSA-5689603 UCH proteinases 75/4920 102/10654 1.624408502255039e-8 6.146410549073121e-8 2.3568942706972118e-8 5689/221937/5682/4738/10445/143471/5705/5709/5695/11047/5711/5683/55777/5699/5702/7040/7345/3054/5696/5691/7314/5718/3607/5700/122706/5707/171023/23198/86/4092/9861/5698/5692/5713/5710/8473/9958/5719/6233/93973/8607/114785/5706/580/5714/5688/5687/5708/125476/5704/7048/7311/60/5694/7528/5684/5720/5690/5717/9491/10197/7316/10213/8314/55252/5715/283899/5701/5685/54617/5686/221656/5716/5693/5721 75 Human_herpesvirus_2 R-HSA-373760 L1CAM interactions 85/4920 119/10654 1.8102425451952837e-8 6.831103944133146e-8 2.6194458733142138e-8 9252/6711/71/7430/1459/51807/347688/1785/1460/10381/8828/4684/3688/1457/285643/5605/7846/3690/6456/1741/1739/3786/6709/5962/163/6196/1759/6197/6334/3312/100133941/5879/6331/6900/6326/161/5594/284217/2260/3672/8650/6714/10376/6195/214/7410/51332/3685/1213/1211/1175/1173/84617/6712/3674/10382/7277/3678/4478/160/3912/3785/26052/6710/27330/6386/2048/3897/10383/24137/1956/60/84790/5058/7280/5595/6328/5604/10048/3915/57731/3673/6708/1742/287 85 Human_herpesvirus_2 R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 41/4920 48/10654 1.8313413380805462e-8 6.873667220677653e-8 2.6357671297335363e-8 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/8812/905/2071/5432/22916/6917/5440/902/5430/6749/5441/7469/4686/9150/5437/6827/2968/1022/8178 41 Human_herpesvirus_2 R-HSA-418597 G alpha (z) signalling events 41/4920 48/10654 1.8313413380805462e-8 6.873667220677653e-8 2.6357671297335363e-8 2788/5579/2770/5578/107/2782/6004/2773/2787/10681/112/111/2792/5588/2785/2783/2784/2771/5580/196883/115/5999/2791/150/113/2786/109/151/54331/59345/51764/94235/114/108/55970/2778/346562/152/2793/5581/2790 41 Human_herpesvirus_2 R-HSA-166208 mTORC1-mediated signalling 23/4920 23/10654 1.8636275834746652e-8 6.9023243832395e-8 2.6467559665053723e-8 6198/29904/10325/2475/10670/64121/84335/1981/1977/1978/57521/28956/6194/389541/58528/64223/6009/1975/55004/7529/153129/8649/10542 23 Human_herpesvirus_2 R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 23/4920 23/10654 1.8636275834746652e-8 6.9023243832395e-8 2.6467559665053723e-8 5431/5435/5433/5439/51497/5438/7936/6829/25920/2963/5434/5436/2962/5432/22916/5440/5430/5441/7469/4686/9150/5437/6827 23 Human_herpesvirus_2 R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 23/4920 23/10654 1.8636275834746652e-8 6.9023243832395e-8 2.6467559665053723e-8 11065/7321/8697/51529/29945/51434/29882/7314/996/983/51433/119504/7324/64682/6233/246184/8881/891/10393/7311/25906/991/7316 23 Human_herpesvirus_2 R-HSA-5654695 PI-3K cascade:FGFR2 23/4920 23/10654 1.8636275834746652e-8 6.9023243832395e-8 2.6467559665053723e-8 5295/2250/2885/2252/2253/5290/8823/8074/2249/2248/2247/2246/2251/5781/2263/2549/8822/8817/2254/26281/10818/2255/27006 23 Human_herpesvirus_2 R-HSA-5654699 SHC-mediated cascade:FGFR2 23/4920 23/10654 1.8636275834746652e-8 6.9023243832395e-8 2.6467559665053723e-8 4893/2250/2885/2252/2253/3845/3265/8823/8074/2249/2248/2247/2246/2251/6464/2263/6654/8822/8817/2254/26281/2255/27006 23 Human_herpesvirus_2 R-HSA-8986944 Transcriptional Regulation by MECP2 50/4920 62/10654 2.435776197864747e-8 8.997590176809092e-8 3.4502037520095014e-008 627/2290/79718/5770/817/9212/27327/6657/28996/9612/4988/192669/4204/3654/4343/6750/814/818/54487/4208/3066/26523/801/2891/805/2904/3930/54715/4233/6515/5566/816/25942/27161/815/8841/5468/4986/57690/192670/9611/2874/2289/2903/3064/5728/3065/23112/1385/808 50 Human_herpesvirus_2 R-HSA-111996 Ca-dependent events 34/4920 38/10654 2.5418284282834923e-8 9.312113153582066e-8 3.570810307012672e-8 817/5578/107/814/818/5567/5594/112/5573/111/5580/5153/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5321/5575/114/108/5576/1385/808/5137 34 Human_herpesvirus_2 R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 29/4920 31/10654 2.5475280984442366e-8 9.312113153582066e-8 3.570810307012672e-8 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/3837/81929/9631/79023/23636/53371/9688/8480 29 Human_herpesvirus_2 R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 29/4920 31/10654 2.5475280984442366e-8 9.312113153582066e-8 3.570810307012672e-8 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/81929/9631/79023/23636/53371/9688/8480 29 Human_herpesvirus_2 R-HSA-5654687 Downstream signaling of activated FGFR1 29/4920 31/10654 2.5475280984442366e-8 9.312113153582066e-8 3.570810307012672e-8 5295/4893/2250/5335/2885/2253/3845/3265/5290/23768/8074/2260/2249/2248/2247/2246/2251/5781/6464/23767/6654/2549/8822/10817/2254/26281/10818/2255/27006 29 Human_herpesvirus_2 R-HSA-351202 Metabolism of polyamines 48/4920 59/10654 2.7321333184651846e-8 9.847998781033377e-8 3.776300284456408e-8 5689/5682/143471/5705/5709/5695/5711/4946/5683/5699/5702/5696/5691/5718/1728/5700/122706/5707/23198/6723/9861/5698/5692/5713/5710/5719/6303/5706/5714/5688/5687/5708/5704/5694/5684/5720/5690/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 48 Human_herpesvirus_2 R-HSA-380108 Chemokine receptors bind chemokines 48/4920 59/10654 2.7321333184651846e-8 9.847998781033377e-8 3.776300284456408e-8 729230/7852/1237/6349/3576/6360/2920/2921/1236/6370/58191/1524/643/2833/6347/6387/10663/3579/6367/2826/6376/3627/6346/1233/6366/6373/6357/10803/6351/3577/10563/10850/5473/4283/6356/56477/1234/57007/6374/1230/2919/5196/6352/6348/6364/6372/6363/1232 48 Human_herpesvirus_2 R-HSA-1538133 G0 and Early G1 26/4920 27/10654 2.73633680415856e-8 9.847998781033377e-8 3.776300284456408e-8 9134/1869/4609/5928/990/8900/7027/7153/898/5934/993/890/983/1859/286826/5111/91750/1874/55957/1017/4605/4149/1875/5933/3065/132660 26 Human_herpesvirus_2 R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 26/4920 27/10654 2.73633680415856e-8 9.847998781033377e-8 3.776300284456408e-8 5431/5435/5433/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/5440/902/5430/5441/8731/5437/2968/1022 26 Human_herpesvirus_2 R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 26/4920 27/10654 2.73633680415856e-8 9.847998781033377e-8 3.776300284456408e-8 5431/5435/5433/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/5440/902/5430/5441/8731/5437/2968/1022 26 Human_herpesvirus_2 R-HSA-912526 Interleukin receptor SHC signaling 26/4920 27/10654 2.73633680415856e-8 9.847998781033377e-8 3.776300284456408e-8 5295/5777/1437/5291/3558/3717/3563/2885/9846/5290/1439/3718/3567/3562/6464/1438/8503/3636/6654/3716/5293/3561/3568/3560/5296/3559 26 Human_herpesvirus_2 R-HSA-1250196 SHC1 events in ERBB2 signaling 22/4920 22/10654 4.0453426842594185e-8 1.4337923437881482e-7 5.4980007167816205e-8 4893/5578/2064/145957/9542/2885/3845/3265/1839/2065/2069/5580/6464/5782/3084/6654/10718/1956/685/1950/2066/5581 22 Human_herpesvirus_2 R-HSA-198753 ERK/MAPK targets 22/4920 22/10654 4.0453426842594185e-8 1.4337923437881482e-7 5.4980007167816205e-8 9252/1848/1432/6196/5518/6197/51231/5515/1849/5594/5528/5519/5598/4208/6195/5600/1846/5595/5516/1845/4205/2002 22 Human_herpesvirus_2 R-HSA-392170 ADP signalling through P2Y purinoceptor 12 22/4920 22/10654 4.0453426842594185e-8 1.4337923437881482e-7 5.4980007167816205e-8 2788/64805/2770/2782/2773/2787/10681/2792/2785/2783/2784/2771/2791/2786/54331/59345/51764/94235/55970/346562/2793/2790 22 Human_herpesvirus_2 R-HSA-5654712 FRS-mediated FGFR4 signaling 22/4920 22/10654 4.0453426842594185e-8 1.4337923437881482e-7 5.4980007167816205e-8 4893/9965/2264/2885/2253/3845/3265/8823/8074/2249/2247/2246/2251/5781/6654/8822/8817/10817/2254/152831/26281/10818 22 Human_herpesvirus_2 R-HSA-5655332 Signaling by FGFR3 in disease 22/4920 22/10654 4.0453426842594185e-8 1.4337923437881482e-7 5.4980007167816205e-8 5295/4893/2250/5335/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/6654/2549/8822/8817/2254/26281/10818/2261 22 Human_herpesvirus_2 R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 22/4920 22/10654 4.0453426842594185e-8 1.4337923437881482e-7 5.4980007167816205e-8 5295/4893/2250/5335/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/6654/2549/8822/8817/2254/26281/10818/2261 22 Human_herpesvirus_2 R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 49/4920 61/10654 4.292240763007553e-8 1.5174588556087308e-7 5.818827190680095e-8 71/51517/10094/8976/2885/5879/25/1072/10093/10006/4771/5594/4644/4641/10810/7410/7409/23191/10109/2214/5747/2209/10451/6850/10092/4650/10163/55845/998/695/3326/10097/60/5058/63916/5595/4690/4627/10458/919/10552/4620/917/3320/1398/10096/7454/10095/2212 49 Human_herpesvirus_2 R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 28/4920 30/10654 5.1857344438634876e-8 1.8241276938213274e-7 6.994775367284789e-8 56852/5982/9978/57599/6117/10714/7314/51514/6118/5985/5984/6233/5424/8451/8450/5425/5111/6119/5427/1642/7311/5983/57804/7320/7316/5426/7398/5981 28 Human_herpesvirus_2 R-HSA-180786 Extension of Telomeres 28/4920 30/10654 5.1857344438634876e-8 1.8241276938213274e-7 6.994775367284789e-8 2237/1763/5982/5422/6117/10714/5558/6118/3978/5557/5985/5984/23649/8607/5424/55651/5425/5111/6119/5427/55135/5983/7015/57804/10856/5426/1736/5981 28 Human_herpesvirus_2 R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 45/4920 55/10654 5.393857616171523e-8 1.8925816197093062e-7 7.257267865050723e-8 51807/347688/10381/1780/3305/8655/832/7846/3306/3312/51164/3303/3337/10376/3301/10540/140735/84617/5241/11258/1783/10382/10294/55860/830/7277/10671/1639/2908/51143/3326/367/10383/84790/3304/7280/10728/829/1778/1781/2289/10121/3320/10963/2288 45 Human_herpesvirus_2 R-HSA-167169 HIV Transcription Elongation 39/4920 46/10654 6.338501862827701e-8 2.207438459691239e-7 8.464613642425051e-8 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/7469/4686/9150/5437/6827/2968/1022/8178 39 Human_herpesvirus_2 R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 39/4920 46/10654 6.338501862827701e-8 2.207438459691239e-7 8.464613642425051e-8 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/7469/4686/9150/5437/6827/2968/1022/8178 39 Human_herpesvirus_2 R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 39/4920 46/10654 6.338501862827701e-8 2.207438459691239e-7 8.464613642425051e-8 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/7469/4686/9150/5437/6827/2968/1022/8178 39 Human_herpesvirus_2 R-HSA-73894 DNA Repair 202/4920 334/10654 6.904443387048773e-8 2.3985659409102434e-7 9.19750849521973e-8 2237/4436/221120/83990/151987/9156/2074/1763/7486/4913/56852/10445/5982/11200/472/6613/27434/5431/5435/9978/5433/85015/10980/64421/4683/2965/25898/165918/84126/5439/10987/8900/8924/57599/2067/672/2967/6612/121642/6117/7334/10973/10714/55666/348654/91603/83695/55183/7314/51514/7014/6118/2176/25/5888/322/328/51588/51720/63967/404672/5531/9636/86/5438/3978/11201/116028/890/1643/7517/9656/51455/2177/5985/10920/29089/2068/7157/5984/4595/4255/6233/7158/6047/93973/55247/8607/7874/5884/5810/5424/5886/8451/8554/10450/8467/80010/3838/5434/5436/2956/7515/7013/4292/7706/51567/580/11073/5591/8450/4331/5425/641/5111/2966/6119/3364/22976/10524/5427/144715/1161/1642/142/125476/1111/2071/55215/1069/7329/9246/79728/51426/2873/7311/4968/3980/60/5536/8533/5983/2175/2547/79840/5432/51138/7528/9318/1017/25913/6917/5440/2178/902/5883/27339/5430/10111/57804/7320/7520/675/51548/545/5441/7336/2072/7316/6996/64708/8314/5426/9100/10635/7415/5395/283899/7341/5437/51008/10401/54617/2033/7398/2968/5932/2138/2189/79184/56949/7156/5887/9716/5599/5981/57461/1022/2139/8178/5980/7508 202 Human_herpesvirus_2 R-HSA-180910 Vpr-mediated nuclear import of PICs 30/4920 33/10654 7.627514125962615e-8 2.636671549715472e-7 1.0110545040262336e-7 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/3159/79023/23636/53371/9688/8815/8480 30 Human_herpesvirus_2 R-HSA-68962 Activation of the pre-replicative complex 30/4920 33/10654 7.627514125962615e-8 2.636671549715472e-7 1.0110545040262336e-7 5422/4174/84515/4998/10926/990/55388/6117/5001/5558/6118/23594/5557/4175/23649/4999/4172/5000/8318/4173/51053/6119/5427/81620/23595/4176/1017/8317/5426/4171 30 Human_herpesvirus_2 R-HSA-6807878 COPI-mediated anterograde transport 73/4920 101/10654 8.317814912350921e-8 2.868212038741697e-7 1.099840706585162e-7 6811/6711/11014/51807/347688/5861/10381/1780/9570/8655/832/7846/9382/3630/6709/10652/54732/51164/2801/10466/1315/8615/11316/91949/8729/10376/1314/10540/51332/378/140735/10959/22820/84617/11258/6712/1783/10382/55860/830/7277/10671/966/1639/10282/6710/8775/81876/51143/10383/84790/7280/829/1778/11070/25839/83548/1604/1781/57731/10121/2804/9527/57511/10972/381/6708/4905/9276/287/375/64689/22818 73 Human_herpesvirus_2 R-HSA-9006931 Signaling by Nuclear Receptors 183/4920 299/10654 8.656449174707002e-8 2.9776483647640797e-7 1.1418050120523914e-7 5295/2788/5161/374/3725/4893/857/79718/7031/5160/5165/2770/10901/7039/27327/10274/8644/8050/5431/5435/5433/1509/5469/9612/4609/55818/1387/8312/2782/5439/192669/10499/1386/5914/4343/3845/904/1071/3265/8877/216/2773/10062/2787/6387/1839/5290/4316/5594/2069/10681/1737/5481/5438/348/4313/865/1655/6667/2792/6714/2099/8850/5467/10000/5162/2785/595/2783/2784/2771/7514/1025/2353/255324/5164/26523/801/29116/2791/2957/805/5105/5170/2963/3838/5434/5590/6464/112724/1374/5241/6319/5747/5436/1903/3315/4318/5885/19/7033/2962/8503/10524/5346/2171/8243/4602/2786/208/3326/6908/1956/5536/3169/51109/858/5432/3480/10728/5595/7528/3727/27161/2354/596/5440/8841/685/54331/347/2309/59345/8204/5430/207/5451/2625/57690/1027/51764/94235/5441/10735/6720/192670/2100/1950/9611/55970/2874/2194/4314/346562/2289/7391/2958/5163/5437/2793/3320/2033/221656/4846/9126/3065/2002/2066/861/23028/6256/23112/7376/10498/1385/1738/5296/808/3276/8202/8648/2288/2790 183 Human_herpesvirus_2 R-HSA-389513 CTLA4 inhibitory signaling 21/4920 21/10654 8.780185499434662e-8 3.0054424692441387e-7 1.1524629017402336e-7 5526/941/2534/5518/5515/5528/6714/5519/10000/7525/3932/5781/1493/4067/5529/208/5516/5525/207/942/5527 21 Human_herpesvirus_2 R-HSA-6807004 Negative regulation of MET activity 21/4920 21/10654 8.780185499434662e-8 3.0054424692441387e-7 1.1524629017402336e-7 5770/3082/6456/30011/2885/7314/8027/2060/9101/9146/6455/6233/4233/5795/5771/7311/26018/7316/867/10254/6457 21 Human_herpesvirus_2 R-HSA-194315 Signaling by Rho GTPases 265/4920 455/10654 8.928575236300616e-8 3.0487817880050884e-7 1.1690817382575902e-7 55839/11130/7984/71/6249/51517/5579/57522/392/9735/7531/55789/5526/29/51807/2909/10971/5578/9212/347688/613/1894/388/7533/2810/147841/348995/10381/57122/6280/1780/23122/3688/5048/57405/8655/10094/23279/5881/1432/2017/2491/7846/23365/79784/9475/1060/9322/397/4628/11004/8976/1855/2885/23433/6093/9184/8997/8826/10499/5518/26084/8874/23332/25909/10726/81930/5062/55746/9411/2665/5879/5515/9181/85415/25/79682/1072/10403/4638/25936/4659/10093/1856/10006/4771/2245/389/5594/29127/3619/64105/89839/7534/332/5528/6453/9828/6714/79902/3796/5519/81565/999/89953/10810/85360/91687/10376/57584/11113/58504/83540/7410/5580/7409/9055/128239/1857/4649/23191/7514/54820/1729/6396/5600/91614/801/64946/9793/30849/10109/5586/140735/5500/4221/805/3831/220134/5170/84617/4928/9743/445328/5590/5903/653361/55055/5747/80776/1783/401541/2316/7532/3633/10382/7074/10627/79172/7277/10451/79980/58480/6232/5501/6279/54821/10092/9183/4650/10163/1062/699/752/22919/55845/5063/3895/57514/5529/51143/998/695/10788/6654/10097/57120/367/10383/5347/387/6655/60/84790/84643/5058/5924/7280/4629/7529/5595/64130/1778/5516/5905/81929/27035/54908/55143/1495/1499/5525/4690/1058/991/79019/57580/4627/10928/348235/80152/10458/1063/3985/8379/1027/9459/1080/23421/55920/79023/6242/1781/9824/10398/4085/5289/5585/5216/10552/55166/4637/1123/995/79003/23028/2/1742/90627/5527/10096/7454/701/23380/9928/29941/3799/103910/57551/5296/5300/84986/808/10095/4952 265 Human_herpesvirus_2 R-HSA-111933 Calmodulin induced events 32/4920 36/10654 9.631990515169118e-8 3.2730064857370785e-7 1.2550626373879025e-7 817/5578/107/814/818/5567/112/5573/111/5580/5153/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5575/114/108/5576/1385/808/5137 32 Human_herpesvirus_2 R-HSA-111997 CaM pathway 32/4920 36/10654 9.631990515169118e-8 3.2730064857370785e-7 1.2550626373879025e-7 817/5578/107/814/818/5567/112/5573/111/5580/5153/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5575/114/108/5576/1385/808/5137 32 Human_herpesvirus_2 R-HSA-5218920 VEGFR2 mediated vascular permeability 27/4920 29/10654 1.0532096716392515e-7 3.5702022767432254e-7 1.369024933187252e-7 857/2475/5062/5879/57761/1500/10000/3728/7410/7409/801/253260/805/5170/10451/64223/1003/5063/208/79109/5058/1495/1499/207/3320/4846/808 27 Human_herpesvirus_2 R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 34/4920 39/10654 1.0987071257299557e-7 3.7154347246906715e-7 1.424715571121987e-7 83990/9156/1763/7486/5982/472/4683/84126/672/6117/83695/6118/5888/116028/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/1111/5983/5883/10111/675/545/5932/7156 34 Human_herpesvirus_2 R-HSA-1489509 DAG and IP3 signaling 36/4920 42/10654 1.1659558104965747e-7 3.933344902880011e-7 1.5082751131344404e-7 5335/817/5578/107/814/818/5567/112/5573/111/5580/5153/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5575/114/3708/108/10768/5576/1385/5581/808/5137 36 Human_herpesvirus_2 R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 24/4920 25/10654 1.1971948366809932e-7 4.0193591639170035e-7 1.5412580252614072e-7 2308/2475/84335/7249/2932/10000/2931/253260/5170/572/4303/6199/64223/208/79109/1147/2309/842/207/1027/1026/3164/1385/4193 24 Human_herpesvirus_2 R-HSA-9006115 Signaling by NTRK2 (TRKB) 24/4920 25/10654 1.1971948366809932e-7 4.0193591639170035e-7 1.5412580252614072e-7 5295/627/4893/5335/2534/2885/3845/3265/5879/5290/6714/4909/5781/4908/6464/2904/7074/6654/2549/1020/4915/10817/10818/8851 24 Human_herpesvirus_2 R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission 132/4920 206/10654 1.37407876970927e-7 4.602177697590857e-7 1.7647448314070202e-7 2788/5563/4893/5579/5331/23426/2900/2770/51807/817/2550/5578/347688/53632/10381/9463/107/9568/7846/9495/2782/1134/1741/1739/163/6196/1740/8874/6197/8825/3845/3265/814/2773/5879/2787/5923/818/161/5567/4646/5594/51422/10681/112/5573/2902/111/2901/2792/3359/6714/2567/2785/10376/6195/2783/2784/2906/2771/196883/3759/115/1175/801/2891/2791/4747/805/5170/1173/84617/3838/8573/2904/2890/10382/2556/5568/2036/7277/160/113/80852/10645/55327/5566/84254/2905/5571/27330/23236/3084/816/2786/5577/10369/5562/10383/84790/5564/5565/5924/7280/109/5595/64130/815/54331/28964/5575/59345/51764/94235/114/108/55970/346562/2793/5576/2903/4137/2066/4905/9647/1742/88/1385/808/8536/4193/2790 132 Human_herpesvirus_2 R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 45/4920 56/10654 1.5160442376939074e-7 5.053480792313025e-7 1.9378009053230392e-7 79718/5469/1387/2101/10499/23054/1386/85441/3054/7019/814/23408/5465/2747/4208/6604/55902/6742/801/133522/64216/805/4899/5442/3418/23082/23410/4209/2553/2551/6648/51106/23373/2746/8841/200186/9611/23409/54205/6256/10498/1385/808/8648/10891 45 Human_herpesvirus_2 R-HSA-429914 Deadenylation-dependent mRNA decay 45/4920 56/10654 1.5160442376939074e-7 5.053480792313025e-7 1.9378009053230392e-7 5393/80153/23404/26986/25904/1973/55571/11340/57472/85456/29883/80349/51690/11157/1981/1977/23016/9924/23644/5073/27258/4850/9652/255967/57819/246175/4848/23019/23658/1975/51010/56915/1974/167227/22894/1656/27257/4849/25804/10605/9337/9775/54464/6499/54512 45 Human_herpesvirus_2 R-HSA-9006936 Signaling by TGF-beta family members 73/4920 102/10654 1.6079172395720565e-7 5.346993195726554e-7 2.0503507743011597e-7 10272/892/7321/4738/91851/130399/8239/9612/4609/4089/22938/23327/4088/5499/1030/9110/7040/10589/904/7314/5054/7027/11167/6497/51592/50848/7323/6667/4092/11171/7050/94/5494/9958/9040/6233/7514/1025/57530/5500/4090/4221/4093/5590/9765/269/3726/5501/1024/60436/8812/1874/142/905/4087/7048/7311/387/57154/9241/10273/4086/64750/659/7316/1875/9611/5933/867/3065/6498/657/56288 73 Human_herpesvirus_2 R-HSA-5619084 ABC transporter disorders 58/4920 77/10654 1.6867335181126353e-7 5.595798401321539e-7 2.145757281709763e-7 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/5696/5691/7314/5718/5700/122706/5707/10956/79139/91445/23198/9861/5698/5692/5713/5710/5719/6233/5706/19/335/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/1244/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 58 Human_herpesvirus_2 R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 31/4920 35/10654 1.865954498000551e-7 6.160903503859328e-7 2.362451719525005e-7 23165/91754/348995/57122/23511/23279/23225/9972/8021/55746/10762/983/79902/9883/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/81929/9631/79023/23636/53371/9688/8480 31 Human_herpesvirus_2 R-HSA-432720 Lysosome Vesicle Biogenesis 31/4920 35/10654 1.865954498000551e-7 6.160903503859328e-7 2.362451719525005e-7 8906/162/27243/1212/1174/1785/11154/408/6456/3312/10053/9146/4074/6844/1213/1211/23431/8907/351/9179/9829/8905/8673/164/1777/130340/2799/81567/10717/6845/375 31 Human_herpesvirus_2 R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 20/4920 20/10654 1.9054794408364922e-7 6.160903503859328e-7 2.362451719525005e-7 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Human_herpesvirus_2 R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 20/4920 20/10654 1.9054794408364922e-7 6.160903503859328e-7 2.362451719525005e-7 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Human_herpesvirus_2 R-HSA-167044 Signalling to RAS 20/4920 20/10654 1.9054794408364922e-7 6.160903503859328e-7 2.362451719525005e-7 4893/5898/1432/5603/2885/3845/3265/5899/9261/6714/4914/5600/6300/6464/7867/6654/5900/25759/53358/4803 20 Human_herpesvirus_2 R-HSA-5654706 FRS-mediated FGFR3 signaling 20/4920 20/10654 1.9054794408364922e-7 6.160903503859328e-7 2.362451719525005e-7 4893/2250/2885/2253/3845/3265/8823/8074/2249/2247/2246/5781/6654/8822/8817/10817/2254/26281/10818/2261 20 Human_herpesvirus_2 R-HSA-5654719 SHC-mediated cascade:FGFR4 20/4920 20/10654 1.9054794408364922e-7 6.160903503859328e-7 2.362451719525005e-7 4893/9965/2264/2885/2253/3845/3265/8823/8074/2249/2247/2246/2251/6464/6654/8822/8817/2254/152831/26281 20 Human_herpesvirus_2 R-HSA-5654720 PI-3K cascade:FGFR4 20/4920 20/10654 1.9054794408364922e-7 6.160903503859328e-7 2.362451719525005e-7 5295/9965/2264/2885/2253/5290/8823/8074/2249/2247/2246/2251/5781/2549/8822/8817/2254/152831/26281/10818 20 Human_herpesvirus_2 R-HSA-69186 Lagging Strand Synthesis 20/4920 20/10654 1.9054794408364922e-7 6.160903503859328e-7 2.362451719525005e-7 2237/1763/5982/5422/6117/10714/5558/6118/3978/5557/5985/5984/23649/5424/5425/5111/6119/5983/57804/5981 20 Human_herpesvirus_2 R-HSA-8964616 G beta:gamma signalling through CDC42 20/4920 20/10654 1.9054794408364922e-7 6.160903503859328e-7 2.362451719525005e-7 2788/2782/2787/10681/2792/2785/2783/2784/2791/998/2786/5058/54331/59345/9459/51764/94235/55970/2793/2790 20 Human_herpesvirus_2 R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 20/4920 20/10654 1.9054794408364922e-7 6.160903503859328e-7 2.362451719525005e-7 22938/1387/4088/4853/9794/388585/2648/55534/3280/84441/8850/2324/10046/59/4855/23493/4851/23462/2033/3516 20 Human_herpesvirus_2 R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 26/4920 28/10654 2.1338697881308106e-7 6.867626904329046e-7 2.6334509182013634e-7 2788/2770/2782/2787/10681/112/111/2792/2785/2783/2784/2771/2791/9254/150/775/2786/54331/59345/776/51764/94235/55970/152/2793/2790 26 Human_herpesvirus_2 R-HSA-75067 Processing of Capped Intronless Pre-mRNA 26/4920 28/10654 2.1338697881308106e-7 6.867626904329046e-7 2.6334509182013634e-7 51585/81608/1477/53981/134353/11051/8106/1478/23283/6636/10914/6635/7884/6637/10898/51692/22916/1479/79869/29894/4686/8189/10978/6634/55339/6628 26 Human_herpesvirus_2 R-HSA-5696400 Dual Incision in GG-NER 35/4920 41/10654 2.1803819534648029e-7 7.001226456079642e-7 2.6846808215042236e-7 5982/9978/2965/2067/2967/6117/10714/7314/6118/404672/1643/5985/2068/5984/6233/5424/8451/8450/5425/5111/2966/6119/5427/1642/142/2071/51426/7311/5983/57804/2072/7316/5426/2968/5981 35 Human_herpesvirus_2 R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 44/4920 55/10654 2.6623560626708333e-7 8.529287157297864e-7 3.270628909941286e-7 834/4790/7295/29108/1432/10628/5603/83737/3654/7334/1540/3551/7314/257397/23118/841/8517/5970/24145/7128/837/598/10454/6233/5600/6300/5608/4791/351/330/7189/3326/4210/7311/114548/1147/596/6885/842/835/58484/7316/22861/329 44 Human_herpesvirus_2 R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 49/4920 63/10654 2.80274319862393e-7 8.958539904277401e-7 3.4352295873544925e-7 55718/4790/5435/4792/3428/1387/84265/22954/1660/3551/7314/8737/29110/8517/6778/51428/5970/3661/6233/10622/661/11128/4791/9533/3665/5434/10623/7098/9208/5591/7311/51728/171568/10621/2547/1147/5440/6737/1499/7520/5441/51082/4615/7316/55703/27297/4793/5437/2033 49 Human_herpesvirus_2 R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 28/4920 31/10654 2.980899366777619e-7 9.484679803383333e-7 3.6369824809966164e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/2645/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/79023/23636/53371/9688/8480 28 Human_herpesvirus_2 R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 28/4920 31/10654 2.980899366777619e-7 9.484679803383333e-7 3.6369824809966164e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/2645/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/79023/23636/53371/9688/8480 28 Human_herpesvirus_2 R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 19/4920 19/10654 4.134824291633575e-7 1.292132591135492e-6 4.954794146459406e-7 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Human_herpesvirus_2 R-HSA-163615 PKA activation 19/4920 19/10654 4.134824291633575e-7 1.292132591135492e-6 4.954794146459406e-7 107/5567/112/5573/111/196883/115/801/805/5568/113/5566/5577/109/5575/114/108/5576/808 19 Human_herpesvirus_2 R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 19/4920 19/10654 4.134824291633575e-7 1.292132591135492e-6 4.954794146459406e-7 11065/7321/8697/51529/29945/51434/29882/996/51433/119504/7324/64682/246184/8881/10393/51343/25906/991/8556 19 Human_herpesvirus_2 R-HSA-176412 Phosphorylation of the APC/C 19/4920 19/10654 4.134824291633575e-7 1.292132591135492e-6 4.954794146459406e-7 11065/7321/8697/51529/29945/51434/29882/996/983/51433/119504/7324/64682/246184/8881/891/10393/25906/5347 19 Human_herpesvirus_2 R-HSA-3928664 Ephrin signaling 19/4920 19/10654 4.134824291633575e-7 1.292132591135492e-6 4.954794146459406e-7 1947/2051/2050/2047/2534/1948/8440/8874/5062/5879/6714/1949/10627/2049/5063/6386/2048/5058/28964 19 Human_herpesvirus_2 R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 19/4920 19/10654 4.134824291633575e-7 1.292132591135492e-6 4.954794146459406e-7 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Human_herpesvirus_2 R-HSA-77595 Processing of Intronless Pre-mRNAs 19/4920 19/10654 4.134824291633575e-7 1.292132591135492e-6 4.954794146459406e-7 51585/81608/1477/53981/11051/8106/1478/23283/10914/10898/51692/22916/1479/79869/29894/4686/8189/10978/55339 19 Human_herpesvirus_2 R-HSA-8851708 Signaling by FGFR2 IIIa TM 19/4920 19/10654 4.134824291633575e-7 1.292132591135492e-6 4.954794146459406e-7 5431/5435/5433/5439/5438/2247/2246/2963/5434/5436/2263/2962/5432/22916/5440/5430/5441/4686/5437 19 Human_herpesvirus_2 R-HSA-354192 Integrin alphaIIb beta3 signaling 25/4920 27/10654 4.3121891690137557e-7 1.3415699636931686e-6 5.144366026191848e-7 5770/5908/2244/3690/2885/9564/7094/10125/6714/2335/1445/2266/2243/5170/6464/5747/3674/6850/6654/7450/207/54518/1398/10235/5906 25 Human_herpesvirus_2 R-HSA-9006921 Integrin signaling 25/4920 27/10654 4.3121891690137557e-7 1.3415699636931686e-6 5.144366026191848e-7 5770/5908/2244/3690/2885/9564/7094/10125/6714/2335/1445/2266/2243/5170/6464/5747/3674/6850/6654/7450/207/54518/1398/10235/5906 25 Human_herpesvirus_2 R-HSA-112043 PLC beta mediated events 43/4920 54/10654 4.6553450367007394e-7 1.4451181932108724e-6 5.541430665695827e-7 5331/2770/817/5578/107/814/2773/818/5567/5594/112/5573/111/2771/5580/5153/196883/115/801/805/3838/5568/113/10645/5566/84254/23236/816/5577/109/815/5321/5575/114/3708/108/2779/10768/346562/5576/1385/808/5137 43 Human_herpesvirus_2 R-HSA-983169 Class I MHC mediated antigen processing & presentation 218/4920 371/10654 5.064668216880725e-7 1.5687025450515518e-6 6.01532554869392e-7 8454/8773/5689/11065/9666/55070/5682/93611/3107/7321/9021/8697/9817/7174/6478/811/143471/5705/57674/9690/8452/5709/9978/5695/567/54620/4734/7337/7704/3106/3093/5711/23327/51465/10616/5683/3309/89910/25898/5699/7328/7428/5702/22954/83737/51529/10075/29945/8924/56658/51434/10425/25793/3133/29882/7334/92591/55182/84961/3551/7332/5696/5691/9820/55658/7314/996/5718/8945/64410/10952/5700/122706/5707/23198/10533/6892/8517/6810/6477/7323/22872/4008/11059/26118/51433/9861/10134/6502/5698/27246/5692/5713/79654/5710/9040/7324/5719/64682/8925/51191/6233/3685/6047/868/6396/5930/11275/29116/23608/55585/51132/899/3135/23352/653361/246184/151636/10802/10193/6890/821/81559/2209/5706/26263/9554/8881/29927/7317/80196/84078/5714/26272/8651/5688/5687/26270/63893/118424/5708/55008/2923/695/63891/9246/10393/9902/5704/4012/25847/7327/51343/7311/9871/9320/57520/5694/8673/3105/997/140691/57154/1147/5684/6737/8065/5720/84708/7319/54850/26046/991/10273/7320/5690/5717/9491/6500/26259/10197/7099/7336/4615/64750/23376/6891/7316/10213/114907/54926/25831/7322/5715/9867/5701/9341/23291/5685/5686/55521/114609/55294/135892/8453/80176/8139/948/5716/7064/3134/80204/27338/7097/23014/90678/5693/5721 218 Human_herpesvirus_2 R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 22/4920 23/10654 5.20430749015239e-7 1.6048525300029399e-6 6.153945791740597e-7 7321/8239/9612/4089/23327/4088/7314/6497/51592/7323/7050/5494/6233/60436/142/4087/7311/64750/7316/9611/3065/6498 22 Human_herpesvirus_2 R-HSA-5654693 FRS-mediated FGFR1 signaling 22/4920 23/10654 5.20430749015239e-7 1.6048525300029399e-6 6.153945791740597e-7 4893/2250/2885/2253/3845/3265/8074/2260/2249/2248/2247/2246/2251/5781/6654/8822/10817/2254/26281/10818/2255/27006 22 Human_herpesvirus_2 R-HSA-5685942 HDR through Homologous Recombination (HRR) 51/4920 67/10654 5.358441371961858e-7 1.6487511913728794e-6 6.322279004512545e-7 83990/9156/1763/7486/5982/472/4683/84126/672/6117/10714/348654/83695/7314/6118/5888/116028/7517/5985/5984/6233/5884/5810/5424/80010/580/11073/5425/641/5111/6119/3364/10524/5427/144715/1111/79728/51426/7311/5983/5883/10111/57804/675/545/7316/5426/10635/5932/7156/5981 51 Human_herpesvirus_2 R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 27/4920 30/10654 5.864935716915471e-7 1.796698031440188e-6 6.889593955146586e-7 7124/7375/10616/1540/3551/7314/257397/8737/55072/23118/8517/7128/10454/6233/331/8717/330/27005/7311/1147/7186/56957/6885/7316/7132/329/9099 27 Human_herpesvirus_2 R-HSA-6804758 Regulation of TP53 Activity through Acetylation 27/4920 30/10654 5.864935716915471e-7 1.796698031440188e-6 6.889593955146586e-7 64769/84289/29117/5928/1107/5371/23774/3622/27154/57459/10000/7994/3066/7157/5608/7862/9219/5931/1108/54815/208/53615/5305/207/2033/3065/5300 27 Human_herpesvirus_2 R-HSA-73893 DNA Damage Bypass 39/4920 48/10654 6.080432561561848e-7 1.8586475079010014e-6 7.127144579169253e-7 56852/5982/9978/25898/57599/6117/10714/55666/7314/51514/6118/9636/11201/51455/5985/5984/6233/5424/8451/7706/8450/5425/5111/6119/5427/1642/9246/51426/7311/5983/57804/7320/7316/5426/9100/7415/7398/5981/5980 39 Human_herpesvirus_2 R-HSA-2871809 FCERI mediated Ca+2 mobilization 29/4920 33/10654 6.928964191071964e-7 2.1088151885871197e-6 8.086434181800231e-7 5335/5530/2885/4773/5336/7410/7409/3702/801/805/6464/2205/4772/3937/4775/10451/2206/6850/4067/695/6654/9402/5532/3708/10768/27040/5534/808/2207 29 Human_herpesvirus_2 R-HSA-389356 CD28 co-stimulation 29/4920 33/10654 6.928964191071964e-7 2.1088151885871197e-6 8.086434181800231e-7 5295/941/2534/2885/2475/5062/5879/5290/57761/9020/6714/10000/7525/7409/3932/253260/5170/64223/8503/4067/5063/998/208/79109/5058/9402/207/942/5296 29 Human_herpesvirus_2 R-HSA-176033 Interactions of Vpr with host cellular proteins 31/4920 36/10654 7.463038266199035e-7 2.266432445266518e-6 8.690831181097175e-7 23165/348995/57122/23511/292/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/3159/79023/23636/53371/9688/8815/8480 31 Human_herpesvirus_2 R-HSA-70326 Glucose metabolism 65/4920 91/10654 8.573826795079162e-7 2.5981293318421705e-6 9.962751573229373e-7 23165/7167/5313/2806/5211/348995/57122/3099/6576/23511/8789/23279/5106/23225/9972/5518/2538/4191/8021/55746/5515/2597/5567/10762/5528/79902/5519/9883/226/2821/8604/2645/6396/129401/230/5105/4928/5903/55706/7175/2203/5568/2805/4927/5566/2023/4190/8086/5516/81929/9631/5091/5315/79023/23636/5214/53371/5230/10165/3098/9688/5210/5209/5213/8480 65 Human_herpesvirus_2 R-HSA-912694 Regulation of IFNA signaling 24/4920 26/10654 8.690101610886782e-7 2.627676513011122e-6 1.0076052794253174e-6 3443/5777/5770/9021/11274/3445/3444/3451/3448/3439/3452/6773/7297/5781/3446/3455/6772/8651/3440/3454/3716/3456/3441/3449 24 Human_herpesvirus_2 R-HSA-5654221 Phospholipase C-mediated cascade; FGFR2 18/4920 18/10654 8.971438426318761e-7 2.6837636318047575e-6 1.0291123700905461e-6 2250/5335/2252/2253/8823/8074/2249/2248/2247/2246/2251/2263/8822/8817/2254/26281/2255/27006 18 Human_herpesvirus_2 R-HSA-5654704 SHC-mediated cascade:FGFR3 18/4920 18/10654 8.971438426318761e-7 2.6837636318047575e-6 1.0291123700905461e-6 4893/2250/2885/2253/3845/3265/8823/8074/2249/2247/2246/6464/6654/8822/8817/2254/26281/2261 18 Human_herpesvirus_2 R-HSA-5654710 PI-3K cascade:FGFR3 18/4920 18/10654 8.971438426318761e-7 2.6837636318047575e-6 1.0291123700905461e-6 5295/2250/2885/2253/5290/8823/8074/2249/2247/2246/5781/2549/8822/8817/2254/26281/10818/2261 18 Human_herpesvirus_2 R-HSA-73780 RNA Polymerase III Chain Elongation 18/4920 18/10654 8.971438426318761e-7 2.6837636318047575e-6 1.0291123700905461e-6 55718/5435/84265/10622/661/11128/9533/5434/10623/51728/171568/10621/5440/5441/51082/55703/27297/5437 18 Human_herpesvirus_2 R-HSA-8964315 G beta:gamma signalling through BTK 18/4920 18/10654 8.971438426318761e-7 2.6837636318047575e-6 1.0291123700905461e-6 2788/2782/2787/10681/2792/2785/2783/2784/2791/695/2786/54331/59345/51764/94235/55970/2793/2790 18 Human_herpesvirus_2 R-HSA-1236394 Signaling by ERBB4 45/4920 58/10654 9.804267925363505e-7 2.8957753366052548e-6 1.1104100914802104e-6 5295/4893/2670/51741/6776/4734/10413/145957/83737/6868/9542/2885/3845/3265/7314/6387/1839/5290/2065/2069/23118/348/11059/6714/2099/1447/2567/3925/6233/5663/6464/5241/3084/6654/10718/7311/1956/685/7316/1950/9611/2066/6285/1742/11033 45 Human_herpesvirus_2 R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 45/4920 58/10654 9.804267925363505e-7 2.8957753366052548e-6 1.1104100914802104e-6 8454/79718/892/182/9978/9759/9612/4609/22938/1387/6868/9794/388585/7314/79885/2648/9734/51564/55534/3280/84441/10013/3714/102/8850/3066/6233/5663/10046/1024/10014/26508/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/54567/3516 45 Human_herpesvirus_2 R-HSA-2644603 Signaling by NOTCH1 in Cancer 45/4920 58/10654 9.804267925363505e-7 2.8957753366052548e-6 1.1104100914802104e-6 8454/79718/892/182/9978/9759/9612/4609/22938/1387/6868/9794/388585/7314/79885/2648/9734/51564/55534/3280/84441/10013/3714/102/8850/3066/6233/5663/10046/1024/10014/26508/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/54567/3516 45 Human_herpesvirus_2 R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 45/4920 58/10654 9.804267925363505e-7 2.8957753366052548e-6 1.1104100914802104e-6 8454/79718/892/182/9978/9759/9612/4609/22938/1387/6868/9794/388585/7314/79885/2648/9734/51564/55534/3280/84441/10013/3714/102/8850/3066/6233/5663/10046/1024/10014/26508/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/54567/3516 45 Human_herpesvirus_2 R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 45/4920 58/10654 9.804267925363505e-7 2.8957753366052548e-6 1.1104100914802104e-6 8454/79718/892/182/9978/9759/9612/4609/22938/1387/6868/9794/388585/7314/79885/2648/9734/51564/55534/3280/84441/10013/3714/102/8850/3066/6233/5663/10046/1024/10014/26508/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/54567/3516 45 Human_herpesvirus_2 R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 45/4920 58/10654 9.804267925363505e-7 2.8957753366052548e-6 1.1104100914802104e-6 8454/79718/892/182/9978/9759/9612/4609/22938/1387/6868/9794/388585/7314/79885/2648/9734/51564/55534/3280/84441/10013/3714/102/8850/3066/6233/5663/10046/1024/10014/26508/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/54567/3516 45 Human_herpesvirus_2 R-HSA-437239 Recycling pathway of L1 38/4920 47/10654 1.0795112302373449e-6 3.169385741953156e-6 1.2153283672151198e-6 9252/71/7430/51807/347688/1785/10381/285643/7846/6456/5962/163/6196/1759/6197/161/5594/8650/6714/10376/6195/1213/1211/1175/1173/84617/10382/7277/4478/160/26052/27330/3897/10383/24137/60/84790/7280 38 Human_herpesvirus_2 R-HSA-113510 E2F mediated regulation of DNA replication 21/4920 22/10654 1.082118846181149e-6 3.169385741953156e-6 1.2153283672151198e-6 5925/5422/1869/84515/4998/28227/5518/5001/5558/5515/23594/7027/5557/983/5519/23649/4999/5000/891/23595/5516 21 Human_herpesvirus_2 R-HSA-442982 Ras activation upon Ca2+ influx through NMDA receptor 21/4920 22/10654 1.082118846181149e-6 3.169385741953156e-6 1.2153283672151198e-6 4893/817/1741/1739/1740/3845/3265/5923/818/2902/2906/801/4747/805/2904/816/5924/815/1742/88/808 21 Human_herpesvirus_2 R-HSA-912631 Regulation of signaling by CBL 21/4920 22/10654 1.082118846181149e-6 3.169385741953156e-6 1.2153283672151198e-6 5295/5291/2534/2885/1399/7314/5290/6233/7525/7409/6850/8503/2889/4067/7311/5293/7316/3055/867/1398/5296 21 Human_herpesvirus_2 R-HSA-112040 G-protein mediated events 43/4920 55/10654 1.17968888603081e-6 3.4479424643906765e-6 1.322143351006951e-6 5331/2770/817/5578/107/814/2773/818/5567/5594/112/5573/111/2771/5580/5153/196883/115/801/805/3838/5568/113/10645/5566/84254/23236/816/5577/109/815/5321/5575/114/3708/108/2779/10768/346562/5576/1385/808/5137 43 Human_herpesvirus_2 R-HSA-390466 Chaperonin-mediated protein folding 67/4920 95/10654 1.236062883079733e-6 3.605183408982554e-6 1.382438750812859e-6 2788/9134/1459/2770/51807/10528/1460/10381/10576/1457/7846/7411/2782/10574/10693/8877/2773/5201/2787/5204/10575/10681/898/2792/10471/26985/2785/10376/2783/2784/10238/7157/2771/2791/5202/84617/8237/10382/7277/6774/26272/26270/55135/2786/10383/60/84790/22948/7280/10694/8841/54331/22803/59345/5203/51764/94235/2779/7203/908/55970/346562/2793/6950/55294/6499/2790 67 Human_herpesvirus_2 R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 71/4920 102/10654 1.3197399742538733e-6 3.8412390103023344e-6 1.472956312221196e-6 8454/8792/7124/5689/5682/356/143471/5705/5709/5695/7133/5711/5683/5699/5702/60401/958/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/8741/1896/9861/5698/5692/5713/5710/9040/5719/6233/4791/959/8600/330/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/7186/5690/5717/9491/6500/10197/7316/10213/5715/7132/5701/329/23291/5685/5686/5716/5693/5721 71 Human_herpesvirus_2 R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 28/4920 32/10654 1.327599693097692e-6 3.848115052457078e-6 1.4755929900399322e-6 892/4609/4089/22938/4088/1030/904/7314/5054/7027/6667/4092/7050/6233/1025/4221/3726/1024/60436/8812/1874/905/4087/7311/7316/1875/5933/3065 28 Human_herpesvirus_2 R-HSA-381042 PERK regulates gene expression 28/4920 32/10654 1.327599693097692e-6 3.848115052457078e-6 1.4755929900399322e-6 5393/1965/23404/3576/3309/4801/6347/11340/468/3484/1054/8894/9451/8570/23016/1968/5073/1051/4800/51010/56915/167227/22894/440/4802/1649/467/54512 28 Human_herpesvirus_2 R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 32/4920 38/10654 1.3914823576379147e-6 4.0249489683741336e-6 1.5434014841133895e-6 5908/3313/6175/3936/5898/3181/4001/4282/5062/1072/6627/9049/27250/9987/3185/3458/5478/302/552900/6775/4478/998/6648/2939/6888/3586/829/6647/6950/4507/375/5721 32 Human_herpesvirus_2 R-HSA-8953750 Transcriptional Regulation by E2F6 30/4920 35/10654 1.4020439678879931e-6 4.044978713649148e-6 1.5510820631286206e-6 6045/80012/79813/11335/1869/1911/5928/10138/23512/672/6241/5888/7027/2146/1876/8726/8409/7703/317/23429/6015/5931/1111/648/23468/23269/8317/4149/5932/10919 30 Human_herpesvirus_2 R-HSA-445717 Aquaporin-mediated transport 41/4920 52/10654 1.4041854677382042e-6 4.044978713649148e-6 1.5510820631286206e-6 2788/107/554/2782/2787/22841/5567/10681/112/5573/111/2792/2785/2783/2784/196883/115/2791/5568/359/113/5566/282679/2786/5577/109/54331/5575/59345/51764/94235/114/108/8766/55970/2778/2793/5576/4645/551/2790 41 Human_herpesvirus_2 R-HSA-388841 Costimulation by the CD28 family 52/4920 70/10654 1.538111124667062e-6 4.421674691034675e-6 1.69552939280277e-6 5295/5777/5526/941/3113/2534/2885/2475/5518/3127/5062/5879/5515/5290/57761/5528/9020/6714/5519/29126/10000/1445/916/7525/7409/3932/5781/1493/253260/5170/3123/3122/920/64223/8503/4067/5063/5529/998/208/79109/5058/5516/9402/5525/207/919/915/917/942/5527/5296 52 Human_herpesvirus_2 R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 23/4920 25/10654 1.7460643091333509e-6 4.988755168952431e-6 1.9129813053877742e-6 5982/6117/10714/7314/6118/3978/5985/5984/6233/5424/7515/5425/5111/6119/5427/51426/7311/3980/5983/57804/7316/5426/5981 23 Human_herpesvirus_2 R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 23/4920 25/10654 1.7460643091333509e-6 4.988755168952431e-6 1.9129813053877742e-6 5520/8900/28227/5518/7465/5515/993/890/983/5519/7514/2305/9133/891/4331/5347/5516/1017/994/902/9088/995/1022 23 Human_herpesvirus_2 R-HSA-9620244 Long-term potentiation 23/4920 25/10654 1.7460643091333509e-6 4.988755168952431e-6 1.9129813053877742e-6 817/1741/1739/1740/818/2902/6714/2906/801/2891/4747/805/2904/2890/2905/3084/816/815/2903/2066/1742/88/808 23 Human_herpesvirus_2 R-HSA-199977 ER to Golgi Anterograde Transport 100/4920 154/10654 1.8262906407010645e-6 5.20734602236556e-6 1.996801858200328e-6 6811/23256/374/6711/11014/126003/2153/51807/7039/347688/5861/10381/1780/9570/8655/832/3998/7846/9382/375056/3630/6709/10652/54732/51164/58485/10342/4253/2801/10466/22872/1315/8615/55014/11316/91949/8729/10376/1314/10540/51332/27095/378/6396/1453/140735/10959/22820/84617/11258/6712/2890/1783/10382/10802/55860/830/7277/10671/9554/966/1639/10282/6710/8775/81876/51143/51693/23243/5537/9871/10383/84790/1075/7280/829/1778/9919/10113/11070/25839/83548/1604/1781/57731/10121/2804/9527/57511/22870/5265/10972/381/6708/4905/9276/287/375/64689/22818 100 Human_herpesvirus_2 R-HSA-164378 PKA activation in glucagon signalling 17/4920 17/10654 1.9463428623445435e-6 5.493709692101534e-6 2.10661048343743e-6 107/5567/112/5573/111/196883/115/5568/113/5566/5577/109/5575/114/108/2778/5576 17 Human_herpesvirus_2 R-HSA-180292 GAB1 signalosome 17/4920 17/10654 1.9463428623445435e-6 5.493709692101534e-6 2.10661048343743e-6 5295/374/7039/55824/2885/5829/1839/5290/2069/6714/1445/255324/5781/1956/2549/685/1950 17 Human_herpesvirus_2 R-HSA-2033519 Activated point mutants of FGFR2 17/4920 17/10654 1.9463428623445435e-6 5.493709692101534e-6 2.10661048343743e-6 2250/2252/2253/8823/8074/2249/2248/2247/2246/2251/2263/8822/8817/2254/26281/2255/27006 17 Human_herpesvirus_2 R-HSA-432142 Platelet sensitization by LDL 17/4920 17/10654 1.9463428623445435e-6 5.493709692101534e-6 2.10661048343743e-6 5777/5526/5175/2268/1432/5518/5515/5528/5519/5781/338/5529/5516/5321/5525/5527/7804 17 Human_herpesvirus_2 R-HSA-8934593 Regulation of RUNX1 Expression and Activity 17/4920 17/10654 1.9463428623445435e-6 5.493709692101534e-6 2.10661048343743e-6 27327/192669/5371/4343/865/6714/595/896/26523/5781/27161/894/57690/192670/1021/861/23112 17 Human_herpesvirus_2 R-HSA-111931 PKA-mediated phosphorylation of CREB 20/4920 21/10654 2.2454697258697043e-6 6.265097798191311e-6 2.402405922614713e-6 107/5567/112/5573/111/196883/115/801/805/5568/113/5566/5577/109/5575/114/108/5576/1385/808 20 Human_herpesvirus_2 R-HSA-5654688 SHC-mediated cascade:FGFR1 20/4920 21/10654 2.2454697258697043e-6 6.265097798191311e-6 2.402405922614713e-6 4893/2250/2885/2253/3845/3265/8074/2260/2249/2248/2247/2246/2251/6464/6654/8822/2254/26281/2255/27006 20 Human_herpesvirus_2 R-HSA-5654689 PI-3K cascade:FGFR1 20/4920 21/10654 2.2454697258697043e-6 6.265097798191311e-6 2.402405922614713e-6 5295/2250/2885/2253/5290/8074/2260/2249/2248/2247/2246/2251/5781/2549/8822/2254/26281/10818/2255/27006 20 Human_herpesvirus_2 R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 20/4920 21/10654 2.2454697258697043e-6 6.265097798191311e-6 2.402405922614713e-6 25904/55571/55835/57472/85456/29883/1263/7832/10769/7157/5325/4869/4850/246175/4848/23019/4849/9337/28984/995 20 Human_herpesvirus_2 R-HSA-202040 G-protein activation 25/4920 28/10654 2.24648506763717e-6 6.265097798191311e-6 2.402405922614713e-6 2788/2770/4988/2782/2773/2787/10681/5443/2792/2785/2783/2784/2771/2791/2786/54331/59345/51764/94235/2779/5173/55970/346562/2793/2790 25 Human_herpesvirus_2 R-HSA-350054 Notch-HLH transcription pathway 25/4920 28/10654 2.24648506763717e-6 6.265097798191311e-6 2.402405922614713e-6 79718/9759/9612/22938/1387/4853/9794/79885/2648/9734/51564/55534/84441/10013/4854/8850/3066/10046/10014/4855/4851/8841/9611/3065/3516 25 Human_herpesvirus_2 R-HSA-4551638 SUMOylation of chromatin organization proteins 52/4920 71/10654 3.172078580049939e-6 8.811329389027607e-6 3.3787804424090828e-6 1912/23165/6045/80012/348995/6613/57122/23511/9759/1911/23279/23225/23512/57332/1107/9972/6612/8021/55746/10762/79902/9883/84733/3066/9063/6396/129401/7703/9189/6015/8554/4928/5903/55706/7175/8535/4927/8086/7329/648/23468/81929/9631/79023/23636/53371/9688/7341/3065/23314/6304/8480 52 Human_herpesvirus_2 R-HSA-70171 Glycolysis 52/4920 71/10654 3.172078580049939e-6 8.811329389027607e-6 3.3787804424090828e-6 23165/7167/5313/5211/348995/57122/3099/23511/23279/23225/9972/5518/8021/55746/5515/2597/5567/10762/5528/79902/5519/9883/226/2821/2645/6396/129401/230/4928/5903/55706/7175/5568/4927/5566/2023/8086/5516/81929/9631/5315/79023/23636/5214/53371/5230/3098/9688/5210/5209/5213/8480 52 Human_herpesvirus_2 R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 22/4920 24/10654 3.4970712214243534e-6 9.637597854319085e-6 3.6956202298516783e-6 2237/1763/5982/5422/6117/10714/5558/6118/3978/5557/5985/5984/23649/5424/5425/5111/6119/5427/5983/57804/5426/5981 22 Human_herpesvirus_2 R-HSA-3371571 HSF1-dependent transactivation 22/4920 24/10654 3.4970712214243534e-6 9.637597854319085e-6 3.6956202298516783e-6 817/3305/1387/2475/3306/3312/818/3303/84335/3337/3297/57521/1410/64223/816/3326/3304/10728/815/3320/2033/2288 22 Human_herpesvirus_2 R-HSA-5627123 RHO GTPases activate PAKs 22/4920 24/10654 3.4970712214243534e-6 9.637597854319085e-6 3.6956202298516783e-6 2017/79784/4628/5062/5879/4638/4659/4771/801/5500/805/2316/10627/5063/998/5058/4629/4627/10398/4637/103910/808 22 Human_herpesvirus_2 R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 22/4920 24/10654 3.4970712214243534e-6 9.637597854319085e-6 3.6956202298516783e-6 374/7039/1839/5594/2069/10000/595/7514/2353/255324/5747/208/1956/5595/596/685/2309/207/1027/1950/2002/1385 22 Human_herpesvirus_2 R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 88/4920 134/10654 3.760827415470843e-6 1.0344122557287191e-5 3.966543236252983e-6 5579/2153/7042/5175/5578/3082/29106/7423/3920/374354/2244/3309/3690/87/10487/7040/5874/54863/350/7043/5054/5099/1072/7018/5340/813/7094/7414/10490/6810/6694/7273/22927/1191/27154/226/2335/5478/94121/2266/5154/7076/2243/801/805/351/135228/7424/2316/3674/7277/334/335/51706/308/197/81/3481/54495/5473/8407/7450/29789/10916/5005/7422/5196/3827/1950/2621/5216/5768/710/6647/5265/7078/2/948/88/1675/3479/5155/51368/808/213/5660/7057/6814 88 Human_herpesvirus_2 R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 34/4920 42/10654 3.846464655501341e-6 1.0558922583729171e-5 4.0489101636856215e-6 2788/1459/2770/1460/10576/1457/2782/10574/10693/2773/2787/10575/10681/2792/2785/2783/2784/2771/2791/2786/22948/10694/54331/59345/51764/94235/2779/7203/908/55970/346562/2793/6950/2790 34 Human_herpesvirus_2 R-HSA-1295596 Spry regulation of FGF signaling 16/4920 16/10654 4.222103460363219e-6 1.1477562804870887e-5 4.401170699612144e-6 8569/2885/5518/7314/5515/5594/6714/6233/5781/673/7311/5595/5516/10253/7316/867 16 Human_herpesvirus_2 R-HSA-156711 Polo-like kinase mediated events 16/4920 16/10654 4.222103460363219e-6 1.1477562804870887e-5 4.401170699612144e-6 5928/7465/993/2305/9133/286826/891/91750/55957/5347/4605/1063/9088/2033/995/132660 16 Human_herpesvirus_2 R-HSA-1963640 GRB2 events in ERBB2 signaling 16/4920 16/10654 4.222103460363219e-6 1.1477562804870887e-5 4.401170699612144e-6 4893/2064/145957/9542/2885/3845/3265/1839/2069/3084/6654/10718/1956/685/1950/2066 16 Human_herpesvirus_2 R-HSA-1963642 PI3K events in ERBB2 signaling 16/4920 16/10654 4.222103460363219e-6 1.1477562804870887e-5 4.401170699612144e-6 5295/2064/145957/9542/2885/1839/5290/2065/2069/3084/10718/1956/2549/685/1950/2066 16 Human_herpesvirus_2 R-HSA-9614657 FOXO-mediated transcription of cell death genes 16/4920 16/10654 4.222103460363219e-6 1.1477562804870887e-5 4.401170699612144e-6 2308/65018/356/1387/4801/604/4303/4800/10370/6794/27113/2309/10018/4802/1649/2033 16 Human_herpesvirus_2 R-HSA-76009 Platelet Aggregation (Plug Formation) 32/4920 39/10654 4.308473192610365e-6 1.168965594894285e-5 4.482499649594626e-6 5770/5908/2244/3690/2885/9564/7094/10125/6714/2335/1445/2266/2243/5170/6464/5747/3674/1277/150/6850/6654/7450/7066/151/207/54518/152/4352/1398/10235/5906/1278 32 Human_herpesvirus_2 R-HSA-164952 The role of Nef in HIV-1 replication and disease pathogenesis 24/4920 27/10654 4.371340114587088e-6 1.1837284642982445e-5 4.539109148812817e-6 162/1174/567/2534/163/55690/5062/5879/51606/161/10053/926/3932/1175/8907/1173/160/920/8905/164/919/130340/3055/375 24 Human_herpesvirus_2 R-HSA-164938 Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 19/4920 20/10654 4.649237645677805e-6 1.2469219739365759e-5 4.781430125621456e-6 162/1174/567/163/55690/51606/161/10053/926/3932/1175/8907/1173/160/920/8905/164/130340/375 19 Human_herpesvirus_2 R-HSA-418217 G beta:gamma signalling through PLC beta 19/4920 20/10654 4.649237645677805e-6 1.2469219739365759e-5 4.781430125621456e-6 2788/5331/2782/2787/10681/2792/2785/2783/2784/2791/23236/2786/54331/59345/51764/94235/55970/2793/2790 19 Human_herpesvirus_2 R-HSA-5625900 RHO GTPases activate CIT 19/4920 20/10654 4.649237645677805e-6 1.2469219739365759e-5 4.781430125621456e-6 388/79784/4628/5879/4659/389/11113/9055/5500/10627/387/4629/4627/1027/10398/4637/1742/9928/103910 19 Human_herpesvirus_2 R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 19/4920 20/10654 4.649237645677805e-6 1.2469219739365759e-5 4.781430125621456e-6 472/1387/51499/7159/637/27166/23368/7157/63970/55240/5366/84883/147923/94241/8626/7161/665/27113/581 19 Human_herpesvirus_2 R-HSA-8876384 Listeria monocytogenes entry into host cells 19/4920 20/10654 4.649237645677805e-6 1.2469219739365759e-5 4.781430125621456e-6 6456/30011/2885/7314/8027/2060/1500/6714/999/9146/6455/6233/4233/7311/1499/7316/867/10254/6457 19 Human_herpesvirus_2 R-HSA-4090294 SUMOylation of intracellular receptors 26/4920 30/10654 4.812484882298093e-6 1.2882368709784571e-5 4.939855670669271e-6 7068/6613/7181/9759/8856/7067/6612/5914/7421/10062/51588/2516/5465/2099/9063/8554/5241/2908/7329/367/6095/5468/7341/10401/6256/7376 26 Human_herpesvirus_2 R-HSA-2559585 Oncogene Induced Senescence 28/4920 33/10654 4.881938027444504e-6 1.3043345874851728e-5 5.00158375652209e-6 27327/5925/2114/1869/4194/1031/192669/1030/4343/7314/7027/5594/6667/7157/6233/26523/1019/1029/7311/2113/5595/57690/192670/7316/1871/1021/23112/4193 28 Human_herpesvirus_2 R-HSA-373755 Semaphorin interactions 48/4920 65/10654 5.1604506488600346e-006 1.3761201730293426e-5 5.2768517913155235e-006 5361/2909/388/2064/5788/3688/54209/23365/79784/2534/9475/8482/4628/6093/10507/5362/5062/5879/1400/1072/7094/389/10371/3672/2932/64218/80031/9723/10154/57556/10627/4233/5063/3326/387/5058/1020/4629/4627/3985/9037/10398/4637/3320/103910/8851/6237/2242 48 Human_herpesvirus_2 R-HSA-381119 Unfolded Protein Response (UPR) 65/4920 94/10654 5.251334310899848e-6 1.3976935428250547e-5 5.359576743163743e-6 5393/10525/1965/2673/1663/23404/5526/811/3576/9570/10130/3309/4801/55062/6745/6347/11340/9820/10488/8720/9695/7094/9114/58477/468/3484/22872/51726/3068/1054/8894/55033/7466/9451/2931/64061/8570/23016/1968/1200/6464/5073/7184/118/1051/84447/5611/4800/1639/10954/90993/51010/56915/167227/22894/4000/10113/440/4802/1649/2081/30827/467/54512/7709 65 Human_herpesvirus_2 R-HSA-391251 Protein folding 69/4920 101/10654 5.318779313357098e-6 1.412958451366212e-5 5.4181113548629175e-6 2788/9134/1459/2770/51807/10528/1460/10381/10576/1457/7846/7411/2782/10574/10693/8877/2773/5201/2787/5204/10575/10681/898/2792/10471/26985/2785/10376/2783/2784/10238/7157/2771/2791/6904/5202/84617/8237/10382/7277/6774/26272/26270/55135/2786/10383/60/84790/22948/7280/10694/8841/54331/22803/59345/5203/51764/94235/2779/7203/908/55970/346562/1155/2793/6950/55294/6499/2790 69 Human_herpesvirus_2 R-HSA-375276 Peptide ligand-binding receptors 124/4920 201/10654 5.87622510631804e-6 1.5580899903116014e-5 5.974630789916667e-6 729230/10316/7852/1237/4987/51289/3060/6349/3576/6360/4985/2920/3061/2921/1236/554/2831/5367/4988/6370/58191/6755/1524/643/185/339403/2847/2833/6347/187/6750/2587/6387/10663/4889/9283/727/1909/117579/3579/2358/5179/27202/6367/8811/56923/2832/2826/6376/5443/3627/6346/51083/1233/6366/2861/728/183/10022/6373/6357/2925/6869/50865/10803/351/8484/6351/6752/84539/6753/3577/5368/6754/8862/301/6751/5020/4829/186/10563/5540/256933/10850/624/4852/5473/4283/10874/6356/56477/129521/1234/57007/283869/4986/6374/5539/2852/1230/4886/2919/5196/3827/5173/2357/6352/6348/1906/6364/5697/6288/6372/719/6363/2359/5660/1325/1232/551/9002/4887/718/623 124 Human_herpesvirus_2 R-HSA-4086398 Ca2+ pathway 46/4920 62/10654 6.5548042980671515e-6 1.7347308161236317e-5 6.6519753099477605e-6 2788/5331/5578/27327/5530/2782/192669/4343/3845/2787/51176/51701/8322/10681/2792/2785/2783/2784/7474/7855/26523/801/2791/805/4772/6934/23236/2786/27161/815/54331/6885/1499/59345/5532/57690/51764/94235/3708/192670/55970/2793/5534/23112/808/2790 46 Human_herpesvirus_2 R-HSA-112409 RAF-independent MAPK1/3 activation 21/4920 23/10654 6.979843866423171e-6 1.836801017479782e-5 7.043372322666831e-6 1844/1850/1848/1852/5605/3717/1847/3569/3572/1849/5594/983/1843/3570/7297/5781/1846/11221/3716/5595/5604 21 Human_herpesvirus_2 R-HSA-73980 RNA Polymerase III Transcription Termination 21/4920 23/10654 6.979843866423171e-6 1.836801017479782e-5 7.043372322666831e-6 55718/4774/5435/84265/10622/661/11128/9533/5434/10623/51728/171568/10621/4784/5440/5441/51082/55703/27297/5437/6741 21 Human_herpesvirus_2 R-HSA-9617324 Negative regulation of NMDA receptor-mediated neuronal transmission 21/4920 23/10654 6.979843866423171e-6 1.836801017479782e-5 7.043372322666831e-6 817/1741/1739/1740/814/818/2902/2906/801/4747/805/2904/2905/816/815/2903/9647/1742/88/808/8536 21 Human_herpesvirus_2 R-HSA-111465 Apoptotic cleavage of cellular proteins 31/4920 38/10654 7.725451411445953e-6 2.021613453462492e-5 7.752051588465196e-6 2339/660/836/324/4001/6709/6093/840/2934/22985/63967/841/100506658/7082/5339/10134/999/5588/5580/839/5747/118/1829/1832/4000/51765/1499/329/4137/7431/6304 31 Human_herpesvirus_2 R-HSA-5696394 DNA Damage Recognition in GG-NER 31/4920 38/10654 7.725451411445953e-6 2.021613453462492e-5 7.752051588465196e-6 10445/9978/10980/10987/7314/86/1643/10920/6233/93973/8607/5886/8451/8450/1642/142/125476/1069/2873/7311/60/8533/51138/7528/9318/7316/64708/283899/54617/5887/7508 31 Human_herpesvirus_2 R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 31/4920 38/10654 7.725451411445953e-6 2.021613453462492e-5 7.752051588465196e-6 1912/1459/6045/80012/1460/28996/1457/1911/6603/10138/57332/57492/86/865/84733/6604/8289/6602/23429/6015/6595/6597/8535/6599/648/6601/23466/6598/2033/6605/861 31 Human_herpesvirus_2 R-HSA-6803529 FGFR2 alternative splicing 23/4920 26/10654 8.470146110809207e-6 2.2123515961068827e-5 8.483453488830902e-6 54845/5431/5435/5433/5439/5438/3185/4670/5725/2963/5434/5436/2962/80004/5432/22916/5440/5430/3178/5441/4686/5437/3187 23 Human_herpesvirus_2 R-HSA-114604 GPVI-mediated activation cascade 29/4920 35/10654 8.520531557466571e-6 2.2213676313693107e-5 8.51802625562668e-6 5295/5777/5291/388/2534/5879/5290/5336/146850/5294/7410/7409/3932/5781/5170/5590/3937/10451/1277/6850/8503/4067/998/387/27040/23533/5296/1278/2207 29 Human_herpesvirus_2 R-HSA-392518 Signal amplification 27/4920 32/10654 9.043557548693788e-6 2.3310737540812124e-5 8.93870386903322e-6 2788/64805/2770/1432/2782/2776/2773/2787/10681/2792/6714/2785/2783/2784/2771/2791/2786/5321/54331/59345/51764/94235/55970/2767/346562/2793/2790 27 Human_herpesvirus_2 R-HSA-451326 Activation of kainate receptors upon glutamate binding 27/4920 32/10654 9.043557548693788e-6 2.3310737540812124e-5 8.93870386903322e-6 2788/5331/2900/2782/1741/1739/2787/10681/2901/2792/2785/2783/2784/801/2791/805/23236/2786/54331/59345/51764/94235/55970/2793/1742/808/2790 27 Human_herpesvirus_2 R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK 25/4920 29/10654 9.09977249179184e-6 2.3310737540812124e-5 8.93870386903322e-6 5563/53632/10325/2475/10670/64121/51422/7249/5494/57521/28956/389541/58528/64223/5571/6794/6009/55004/5562/5564/5565/7248/153129/8649/10542 25 Human_herpesvirus_2 R-HSA-111447 Activation of BAD and translocation to mitochondria 15/4920 15/10654 9.157789748176192e-6 2.3310737540812124e-5 8.93870386903322e-6 7531/10971/7533/2810/637/7534/10000/572/7532/208/7529/5533/596/207/5534 15 Human_herpesvirus_2 R-HSA-1170546 Prolactin receptor signaling 15/4920 15/10654 9.157789748176192e-6 2.3310737540812124e-5 8.93870386903322e-6 8454/6776/9978/3717/5618/8945/2690/5617/6777/5781/1442/2689/6500/25970/2688 15 Human_herpesvirus_2 R-HSA-354194 GRB2:SOS provides linkage to MAPK signaling for Integrins 15/4920 15/10654 9.157789748176192e-6 2.3310737540812124e-5 8.93870386903322e-6 5908/2244/3690/2885/7094/6714/2335/2266/2243/5747/3674/6654/7450/54518/5906 15 Human_herpesvirus_2 R-HSA-372708 p130Cas linkage to MAPK signaling for integrins 15/4920 15/10654 9.157789748176192e-6 2.3310737540812124e-5 8.93870386903322e-6 5908/2244/3690/9564/7094/6714/2335/2266/2243/5747/3674/7450/54518/1398/5906 15 Human_herpesvirus_2 R-HSA-5637810 Constitutive Signaling by EGFRvIII 15/4920 15/10654 9.157789748176192e-6 2.3310737540812124e-5 8.93870386903322e-6 5295/4893/5335/2885/3845/3265/5290/6464/6654/1956/2549/11140/1950/867/3320 15 Human_herpesvirus_2 R-HSA-5637812 Signaling by EGFRvIII in Cancer 15/4920 15/10654 9.157789748176192e-6 2.3310737540812124e-5 8.93870386903322e-6 5295/4893/5335/2885/3845/3265/5290/6464/6654/1956/2549/11140/1950/867/3320 15 Human_herpesvirus_2 R-HSA-5654228 Phospholipase C-mediated cascade; FGFR4 15/4920 15/10654 9.157789748176192e-6 2.3310737540812124e-5 8.93870386903322e-6 5335/9965/2264/2253/8823/8074/2249/2247/2246/2251/8822/8817/2254/152831/26281 15 Human_herpesvirus_2 R-HSA-6785631 ERBB2 Regulates Cell Motility 15/4920 15/10654 9.157789748176192e-6 2.3310737540812124e-5 8.93870386903322e-6 2064/145957/9542/1839/2065/2069/1729/3084/10718/387/1956/685/1950/51072/2066 15 Human_herpesvirus_2 R-HSA-69183 Processive synthesis on the lagging strand 15/4920 15/10654 9.157789748176192e-6 2.3310737540812124e-5 8.93870386903322e-6 2237/1763/5422/6117/10714/5558/6118/3978/5557/23649/5424/5425/5111/6119/57804 15 Human_herpesvirus_2 R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 15/4920 15/10654 9.157789748176192e-6 2.3310737540812124e-5 8.93870386903322e-6 6456/30011/2885/7314/8027/2060/9146/6455/6233/4233/7311/7316/867/10254/6457 15 Human_herpesvirus_2 R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 18/4920 19/10654 9.603049285065262e-6 2.431151717738041e-5 9.32246147403309e-6 1869/4609/5928/990/7027/7153/5934/993/286826/5111/91750/1874/55957/4149/1875/5933/3065/132660 18 Human_herpesvirus_2 R-HSA-392851 Prostacyclin signalling through prostacyclin receptor 18/4920 19/10654 9.603049285065262e-6 2.431151717738041e-5 9.32246147403309e-6 2788/2782/2787/10681/2792/2785/2783/2784/2791/2786/54331/59345/51764/94235/55970/2778/2793/2790 18 Human_herpesvirus_2 R-HSA-6804760 Regulation of TP53 Activity through Methylation 18/4920 19/10654 9.603049285065262e-6 2.431151717738041e-5 9.32246147403309e-6 133383/11200/472/79813/4194/56950/7314/7157/6233/10419/26013/7311/7316/2033/91875/133746/10919/4193 18 Human_herpesvirus_2 R-HSA-114608 Platelet degranulation 84/4920 129/10654 1.021242339111235e-5 2.5807568136385e-5 9.896135150042367e-6 2153/7042/5175/3082/29106/7423/3920/374354/2244/3309/3690/87/10487/7040/5874/54863/350/7043/5054/5099/1072/7018/5340/813/7094/7414/10490/6694/7273/22927/1191/27154/226/2335/5478/94121/2266/5154/7076/2243/801/805/351/135228/7424/2316/3674/7277/334/335/51706/308/197/81/3481/54495/5473/8407/7450/29789/10916/5005/7422/5196/3827/1950/2621/5216/5768/710/6647/5265/7078/2/948/88/1675/3479/5155/51368/808/213/5660/7057 84 Human_herpesvirus_2 R-HSA-422356 Regulation of insulin secretion 55/4920 78/10654 1.1131285805505006e-5 2.8078919149021635e-5 1.0767104335339122e-5 2788/5331/2770/5578/9495/2782/3630/2776/8826/777/2181/6513/2787/5567/10681/112/5573/111/2792/2785/2783/2784/2771/6844/2182/2791/9254/5568/150/5566/775/23236/6514/2786/5577/773/54331/5575/59345/776/51764/94235/114/3708/4082/55970/2778/2767/10768/152/2793/5576/948/5906/2790 55 Human_herpesvirus_2 R-HSA-877300 Interferon gamma signaling 63/4920 92/10654 1.202578597285399e-5 3.028075604675465e-5 1.1611417732214189e-5 80263/5777/960/5770/3107/817/9021/3383/3662/4684/567/6672/3113/3106/3459/3717/5371/3133/3127/4938/4261/818/115362/7412/9830/2634/10612/3458/3661/5580/81603/4940/5781/3660/8554/3135/3665/10379/2633/3123/2209/8638/7706/3122/3394/3663/6772/8651/3659/5771/816/10346/3716/3105/3460/815/6737/4281/3664/4939/7341/3134/5724 63 Human_herpesvirus_2 R-HSA-1980143 Signaling by NOTCH1 52/4920 73/10654 1.2103649956128204e-5 3.0422100428329418e-5 1.1665617457479702e-5 8454/79718/892/182/3091/9978/9759/9612/4609/22938/1387/408/83737/6868/9794/388585/7314/79885/2648/9734/51564/55534/3280/84441/10013/3714/7091/8650/102/8850/3066/6233/5663/409/10046/1024/10014/26508/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/1840/54567/3516 52 Human_herpesvirus_2 R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 28/4920 34/10654 1.5426653567045238e-5 3.8704865580400244e-5 1.484171537293543e-5 7321/9140/9474/3093/64135/83737/1540/7314/29110/9636/7323/23586/7128/3661/51191/6233/55593/54476/7706/9246/7311/5094/57506/84166/7316/7322/54941/5300 28 Human_herpesvirus_2 R-HSA-400253 Circadian Clock 50/4920 70/10654 1.571867034718934e-5 3.9366974035894586e-5 1.509560658519266e-5 8454/79718/5936/28999/3091/5469/1387/150094/5499/10499/23054/1386/23411/85441/7314/5054/8945/1454/5465/4208/6604/6233/8864/1453/5500/1374/406/4209/5501/8553/2908/1390/7311/23373/6095/8841/8204/6500/200186/1408/6720/7316/9611/2033/6256/10498/1385/8648/551/10891 50 Human_herpesvirus_2 R-HSA-418592 ADP signalling through P2Y purinoceptor 1 22/4920 25/10654 1.6337788578225305e-5 4.0626827725604665e-5 1.557870837598374e-5 2788/1432/2782/2776/2787/10681/2792/6714/2785/2783/2784/2791/2786/5321/54331/59345/51764/94235/55970/2767/2793/2790 22 Human_herpesvirus_2 R-HSA-429947 Deadenylation of mRNA 22/4920 25/10654 1.6337788578225305e-5 4.0626827725604665e-5 1.557870837598374e-5 26986/25904/1973/55571/57472/85456/29883/1981/1977/9924/5073/4850/255967/246175/4848/23019/1975/1974/4849/10605/9337/9775 22 Human_herpesvirus_2 R-HSA-8854691 Interleukin-20 family signaling 22/4920 25/10654 1.6337788578225305e-5 4.0626827725604665e-5 1.557870837598374e-5 11009/6776/3717/282618/50604/3588/55801/3718/6777/6773/7297/5781/6775/50616/53833/6774/6772/29949/163702/3716/58985/53832 22 Human_herpesvirus_2 R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 22/4920 25/10654 1.6337788578225305e-5 4.0626827725604665e-5 1.557870837598374e-5 22938/1387/9794/9787/388585/23286/2648/55534/3280/84441/4854/10320/8850/5087/10046/6772/26508/23493/4851/23462/2033/3516 22 Human_herpesvirus_2 R-HSA-5619115 Disorders of transmembrane transporters 109/4920 176/10654 1.6545664165852905e-5 4.107079757481217e-5 1.5748952453499404e-5 23165/5689/6507/5682/285195/348995/143471/57122/5705/23511/5709/5695/554/6523/23279/5711/10999/23225/5683/5699/6400/5702/4891/1836/9972/8021/55746/55630/5696/5691/6513/7314/5718/5700/122706/5707/10956/79139/91445/23198/10762/9861/79902/9883/283652/5698/5692/5713/5710/5719/6233/6575/2645/6396/129401/4928/5903/55706/7175/7355/5706/9843/19/335/5714/4927/5688/5687/5708/8086/6514/5704/7311/11160/5694/9197/81929/5684/5720/9631/5690/5717/9491/1080/79023/23636/10197/1244/7316/10213/53371/3098/9688/7415/6519/5715/5701/5685/682/5686/6520/5716/213/5693/551/5721/6566/8480/1356 109 Human_herpesvirus_2 R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 24/4920 28/10654 1.7120470396286612e-5 4.242240452177213e-5 1.626723782413819e-5 10381/10576/7846/7411/10574/10693/5201/5204/10575/10471/5202/84617/10382/7277/10383/60/84790/22948/7280/10694/5203/7203/908/6950 24 Human_herpesvirus_2 R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 179/4920 309/10654 1.730518643990083e-5 4.280434808456035e-5 1.6413697385808857e-5 8454/5689/11065/9666/55070/5682/93611/7321/9021/8697/9817/7174/6478/143471/5705/57674/9690/8452/5709/9978/5695/54620/4734/7337/7704/3093/5711/23327/51465/10616/5683/89910/25898/5699/7328/7428/5702/22954/83737/51529/10075/29945/8924/56658/51434/10425/25793/29882/7334/92591/55182/84961/7332/5696/5691/9820/55658/7314/996/5718/8945/64410/5700/122706/5707/23198/10533/6477/7323/4008/11059/26118/51433/9861/6502/5698/27246/5692/5713/79654/5710/9040/7324/5719/64682/8925/51191/6233/6047/868/5930/11275/29116/23608/55585/51132/899/23352/246184/151636/10193/81559/5706/26263/8881/7317/80196/84078/5714/26272/8651/5688/5687/26270/63893/118424/5708/55008/63891/9246/10393/5704/4012/25847/7327/51343/7311/9320/57520/5694/997/140691/57154/5684/6737/8065/5720/84708/7319/54850/26046/991/10273/7320/5690/5717/9491/6500/26259/10197/7336/64750/23376/7316/10213/114907/54926/25831/7322/5715/9867/5701/23291/5685/5686/55521/55294/135892/8453/80176/8139/5716/7064/80204/27338/23014/90678/5693/5721 179 Human_herpesvirus_2 R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 17/4920 18/10654 1.9782726197459796e-5 4.744988587104208e-5 1.819506901821914e-5 5295/11052/613/6776/11064/2885/9846/7750/8805/26127/5290/399687/6777/1523/9208/6774/6772 17 Human_herpesvirus_2 R-HSA-210993 Tie2 Signaling 17/4920 18/10654 1.9782726197459796e-5 4.744988587104208e-5 1.819506901821914e-5 5295/4893/5291/2885/3845/3265/5290/5781/6464/7010/2888/2886/6654/285/5296/284/9046 17 Human_herpesvirus_2 R-HSA-5675482 Regulation of necroptotic cell death 17/4920 18/10654 1.9782726197459796e-5 4.744988587104208e-5 1.819506901821914e-5 356/7314/8737/841/8797/6233/8772/331/8717/330/8837/7311/8795/7186/355/7316/329 17 Human_herpesvirus_2 R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 17/4920 18/10654 1.9782726197459796e-5 4.744988587104208e-5 1.819506901821914e-5 2810/6790/1647/7027/5934/983/7157/891/5111/1874/25946/5933/2033/995/10498/581/3276 17 Human_herpesvirus_2 R-HSA-1250347 SHC1 events in ERBB4 signaling 14/4920 14/10654 1.9861166514593328e-5 4.744988587104208e-5 1.819506901821914e-5 4893/145957/9542/2885/3845/3265/1839/2069/6464/3084/6654/10718/685/2066 14 Human_herpesvirus_2 R-HSA-169893 Prolonged ERK activation events 14/4920 14/10654 1.9861166514593328e-5 4.744988587104208e-5 1.819506901821914e-5 5605/1399/5594/4914/673/2889/7529/5595/5604/57498/10818/4803/1398/5906 14 Human_herpesvirus_2 R-HSA-174411 Polymerase switching on the C-strand of the telomere 14/4920 14/10654 1.9861166514593328e-5 4.744988587104208e-5 1.819506901821914e-5 5982/5422/10714/5558/5557/5985/5984/23649/5424/5425/5111/5983/57804/5981 14 Human_herpesvirus_2 R-HSA-180336 SHC1 events in EGFR signaling 14/4920 14/10654 1.9861166514593328e-5 4.744988587104208e-5 1.819506901821914e-5 374/4893/7039/2885/3845/3265/1839/2069/255324/6464/6654/1956/685/1950 14 Human_herpesvirus_2 R-HSA-190322 FGFR4 ligand binding and activation 14/4920 14/10654 1.9861166514593328e-5 4.744988587104208e-5 1.819506901821914e-5 9965/2264/2253/8823/8074/2249/2247/2246/2251/8822/8817/2254/152831/26281 14 Human_herpesvirus_2 R-HSA-198323 AKT phosphorylates targets in the cytosol 14/4920 14/10654 1.9861166514593328e-5 4.744988587104208e-5 1.819506901821914e-5 84335/7249/2932/10000/2931/23608/572/208/1147/842/207/1027/1026/4193 14 Human_herpesvirus_2 R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 14/4920 14/10654 1.9861166514593328e-5 4.744988587104208e-5 1.819506901821914e-5 4436/9156/6117/10714/6118/3978/5424/2956/4292/5425/5111/6119/57804/5395 14 Human_herpesvirus_2 R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 14/4920 14/10654 1.9861166514593328e-5 4.744988587104208e-5 1.819506901821914e-5 9134/57060/1869/8900/144455/898/890/7157/79733/1820/1017/25946/1027/1026 14 Human_herpesvirus_2 R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 14/4920 14/10654 1.9861166514593328e-5 4.744988587104208e-5 1.819506901821914e-5 7159/51230/23368/5458/10000/7157/5457/54971/8626/208/7161/25946/207/10848 14 Human_herpesvirus_2 R-HSA-69091 Polymerase switching 14/4920 14/10654 1.9861166514593328e-5 4.744988587104208e-5 1.819506901821914e-5 5982/5422/10714/5558/5557/5985/5984/23649/5424/5425/5111/5983/57804/5981 14 Human_herpesvirus_2 R-HSA-69109 Leading Strand Synthesis 14/4920 14/10654 1.9861166514593328e-5 4.744988587104208e-5 1.819506901821914e-5 5982/5422/10714/5558/5557/5985/5984/23649/5424/5425/5111/5983/57804/5981 14 Human_herpesvirus_2 R-HSA-69166 Removal of the Flap Intermediate 14/4920 14/10654 1.9861166514593328e-5 4.744988587104208e-5 1.819506901821914e-5 2237/1763/5422/6117/10714/5558/6118/5557/23649/5424/5425/5111/6119/57804 14 Human_herpesvirus_2 R-HSA-877312 Regulation of IFNG signaling 14/4920 14/10654 1.9861166514593328e-5 4.744988587104208e-5 1.819506901821914e-5 5777/5770/9021/3459/3717/3458/5781/8554/6772/8651/5771/3716/3460/7341 14 Human_herpesvirus_2 R-HSA-8941856 RUNX3 regulates NOTCH signaling 14/4920 14/10654 1.9861166514593328e-5 4.744988587104208e-5 1.819506901821914e-5 182/22938/1387/9794/2648/55534/3280/84441/8850/864/10046/4851/2033/3516 14 Human_herpesvirus_2 R-HSA-8983432 Interleukin-15 signaling 14/4920 14/10654 1.9861166514593328e-5 4.744988587104208e-5 1.819506901821914e-5 6776/2885/9846/3600/3718/6777/6464/6774/6654/3716/6655/3561/3560/3601 14 Human_herpesvirus_2 R-HSA-9027284 Erythropoietin activates RAS 14/4920 14/10654 1.9861166514593328e-5 4.744988587104208e-5 1.819506901821914e-5 4893/3717/2885/2056/8660/3845/3265/1399/2057/7409/6464/2889/4067/6654 14 Human_herpesvirus_2 R-HSA-167287 HIV elongation arrest and recovery 29/4920 36/10654 2.4428220073738862e-5 5.806368099021121e-5 2.226502053008099e-5 5431/5435/5433/5439/11198/904/51497/5438/1025/7936/6829/25920/2963/5434/5436/2962/8812/905/5432/6917/5440/5430/6749/5441/7469/9150/5437/6827/8178 29 Human_herpesvirus_2 R-HSA-167290 Pausing and recovery of HIV elongation 29/4920 36/10654 2.4428220073738862e-5 5.806368099021121e-5 2.226502053008099e-5 5431/5435/5433/5439/11198/904/51497/5438/1025/7936/6829/25920/2963/5434/5436/2962/8812/905/5432/6917/5440/5430/6749/5441/7469/9150/5437/6827/8178 29 Human_herpesvirus_2 R-HSA-168638 NOD1/2 Signaling Pathway 29/4920 36/10654 2.4428220073738862e-5 5.806368099021121e-5 2.226502053008099e-5 834/1432/5603/83737/3654/7334/1540/3551/7314/257397/23118/841/8517/7128/837/10454/6233/5600/6300/5608/330/7189/7311/1147/6885/842/835/7316/329 29 Human_herpesvirus_2 R-HSA-445144 Signal transduction by L1 19/4920 21/10654 2.7485032883854702e-5 6.488877915243943e-5 2.4882163434394067e-5 1459/1460/4684/3688/1457/5605/3690/5879/5594/2260/7410/3685/3674/3678/3897/1956/5058/5595/5604 19 Human_herpesvirus_2 R-HSA-500657 Presynaptic function of Kainate receptors 19/4920 21/10654 2.7485032883854702e-5 6.488877915243943e-5 2.4882163434394067e-5 2788/5331/2782/2787/10681/2792/2785/2783/2784/2791/23236/2786/54331/59345/51764/94235/55970/2793/2790 19 Human_herpesvirus_2 R-HSA-5218921 VEGFR2 mediated cell proliferation 19/4920 21/10654 2.7485032883854702e-5 6.488877915243943e-5 2.4882163434394067e-5 4893/5335/5579/5578/3845/3265/8877/5921/6714/5580/3791/801/805/5170/5590/7422/3708/10768/808 19 Human_herpesvirus_2 R-HSA-5621575 CD209 (DC-SIGN) signaling 19/4920 21/10654 2.7485032883854702e-5 6.488877915243943e-5 2.4882163434394067e-5 9252/4893/4790/1387/2534/5894/3845/3265/5062/5567/5970/5568/5566/4067/5063/30835/5971/5058/2033 19 Human_herpesvirus_2 R-HSA-2424491 DAP12 signaling 25/4920 30/10654 3.053621053926087e-5 7.184990715120205e-5 2.7551468155724095e-5 5295/4893/5335/5291/54209/567/2534/2885/3133/3845/3265/5879/5290/5336/7410/3932/6464/3937/10451/6850/695/6654/9402/27040/5296 25 Human_herpesvirus_2 R-HSA-499943 Interconversion of nucleotide di- and triphosphates 25/4920 30/10654 3.053621053926087e-5 7.184990715120205e-5 2.7551468155724095e-5 4832/654364/221264/7295/1841/205/7296/6241/158067/203/4831/102157402/4833/7298/50484/204/2745/1854/2987/51727/26289/6240/4830/122481/79077 25 Human_herpesvirus_2 R-HSA-203927 MicroRNA (miRNA) biogenesis 21/4920 24/10654 3.135925238141478e-5 7.366267337916223e-5 2.8246589040129878e-5 5431/5435/5433/5439/192669/29102/5438/54487/57510/26523/23405/5434/5436/5901/5432/27161/5440/5430/5441/192670/5437 21 Human_herpesvirus_2 R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress 23/4920 27/10654 3.203828058908601e-5 7.51316462725635e-5 2.8809879397749917e-5 5393/23404/3576/4801/6347/11340/468/3484/1054/8570/23016/5073/1051/4800/51010/56915/167227/22894/440/4802/1649/467/54512 23 Human_herpesvirus_2 R-HSA-5655862 Translesion synthesis by POLK 16/4920 17/10654 4.063427302866207e-5 9.49715897164055e-5 3.6417677259674287e-5 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/51426/7311/5983/7316/5981/5980 16 Human_herpesvirus_2 R-HSA-5656121 Translesion synthesis by POLI 16/4920 17/10654 4.063427302866207e-5 9.49715897164055e-5 3.6417677259674287e-5 5982/6117/7314/6118/11201/51455/5985/5984/6233/5111/6119/7311/5983/7316/5981/5980 16 Human_herpesvirus_2 R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 13/4920 13/10654 4.3069629688564776e-5 9.884833043277161e-5 3.790424700805528e-5 2064/9542/7314/2065/9101/10000/6233/10193/3084/208/7311/207/7316 13 Human_herpesvirus_2 R-HSA-171007 p38MAPK events 13/4920 13/10654 4.3069629688564776e-5 9.884833043277161e-5 3.790424700805528e-5 4893/5898/1432/5603/3845/3265/5899/9261/6714/5600/6300/7867/5900 13 Human_herpesvirus_2 R-HSA-179812 GRB2 events in EGFR signaling 13/4920 13/10654 4.3069629688564776e-5 9.884833043277161e-5 3.790424700805528e-5 374/4893/7039/2885/3845/3265/1839/2069/255324/6654/1956/685/1950 13 Human_herpesvirus_2 R-HSA-190375 FGFR2c ligand binding and activation 13/4920 13/10654 4.3069629688564776e-5 9.884833043277161e-5 3.790424700805528e-5 2250/2253/8823/8074/2249/2247/2246/2251/2263/8822/8817/2254/26281 13 Human_herpesvirus_2 R-HSA-202670 ERKs are inactivated 13/4920 13/10654 4.3069629688564776e-5 9.884833043277161e-5 3.790424700805528e-5 1848/5518/51231/5515/1849/5594/5528/5519/5598/1846/5595/5516/1845 13 Human_herpesvirus_2 R-HSA-209560 NF-kB is activated and signals survival 13/4920 13/10654 4.3069629688564776e-5 9.884833043277161e-5 3.790424700805528e-5 4790/8878/4792/3654/3551/7314/5970/6233/7189/7311/4804/7316/4803 13 Human_herpesvirus_2 R-HSA-5357786 TNFR1-induced proapoptotic signaling 13/4920 13/10654 4.3069629688564776e-5 9.884833043277161e-5 3.790424700805528e-5 7124/7375/1540/8737/841/7128/8772/8717/27005/7186/56957/7132/9099 13 Human_herpesvirus_2 R-HSA-5654227 Phospholipase C-mediated cascade; FGFR3 13/4920 13/10654 4.3069629688564776e-5 9.884833043277161e-5 3.790424700805528e-5 2250/5335/2253/8823/8074/2249/2247/2246/8822/8817/2254/26281/2261 13 Human_herpesvirus_2 R-HSA-5658623 FGFRL1 modulation of FGFR1 signaling 13/4920 13/10654 4.3069629688564776e-5 9.884833043277161e-5 3.790424700805528e-5 2250/2253/8074/2249/2248/2247/200734/53834/8822/8817/2255/27006/161742 13 Human_herpesvirus_2 R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13/4920 13/10654 4.3069629688564776e-5 9.884833043277161e-5 3.790424700805528e-5 7531/10971/7533/2810/11200/7465/7534/983/7532/891/1111/7529/995 13 Human_herpesvirus_2 R-HSA-8847993 ERBB2 Activates PTK6 Signaling 13/4920 13/10654 4.3069629688564776e-5 9.884833043277161e-5 3.790424700805528e-5 2064/5753/145957/9542/1839/2065/2069/3084/10718/1956/685/1950/2066 13 Human_herpesvirus_2 R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 26/4920 32/10654 4.968950186749125e-5 1.1329853846007777e-4 4.344530422153358e-5 51807/10381/10576/7846/7411/10574/10693/5201/5204/10575/10471/10376/5202/84617/10382/7277/10383/60/84790/22948/7280/10694/5203/7203/908/6950 26 Human_herpesvirus_2 R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 26/4920 32/10654 4.968950186749125e-5 1.1329853846007777e-4 4.344530422153358e-5 2788/408/2768/2782/2776/2787/5594/10681/2792/6714/2785/2783/2784/2791/409/2786/5595/54331/59345/51764/94235/55970/2767/2793/9002/2790 26 Human_herpesvirus_2 R-HSA-5626467 RHO GTPases activate IQGAPs 26/4920 32/10654 4.968950186749125e-5 1.1329853846007777e-4 4.344530422153358e-5 71/6249/51807/347688/10381/7846/8826/5879/999/10376/128239/801/4221/805/84617/10382/7277/998/10788/10383/60/84790/7280/1495/1499/808 26 Human_herpesvirus_2 R-HSA-5656169 Termination of translesion DNA synthesis 26/4920 32/10654 4.968950186749125e-5 1.1329853846007777e-4 4.344530422153358e-5 5982/6117/10714/7314/6118/9636/11201/51455/5985/5984/6233/5424/7706/5425/5111/6119/5427/9246/51426/7311/5983/57804/7316/5426/9100/5981 26 Human_herpesvirus_2 R-HSA-3232118 SUMOylation of transcription factors 18/4920 20/10654 5.4187354039552315e-5 1.2275452371419618e-4 4.707128352950379e-5 9112/6613/7022/6612/6670/51588/7157/7158/9063/8554/7020/1029/7329/7021/3090/7341/10401/4193 18 Human_herpesvirus_2 R-HSA-5213460 RIPK1-mediated regulated necrosis 18/4920 20/10654 5.4187354039552315e-5 1.2275452371419618e-4 4.707128352950379e-5 356/7314/8737/841/8797/6233/8772/331/8717/330/8837/197259/7311/8795/7186/355/7316/329 18 Human_herpesvirus_2 R-HSA-5218859 Regulated Necrosis 18/4920 20/10654 5.4187354039552315e-5 1.2275452371419618e-4 4.707128352950379e-5 356/7314/8737/841/8797/6233/8772/331/8717/330/8837/197259/7311/8795/7186/355/7316/329 18 Human_herpesvirus_2 R-HSA-5627117 RHO GTPases Activate ROCKs 18/4920 20/10654 5.4187354039552315e-5 1.2275452371419618e-4 4.707128352950379e-5 388/79784/9475/4628/6093/1072/4659/389/5500/10627/387/5058/4629/4627/3985/10398/4637/103910 18 Human_herpesvirus_2 R-HSA-8856688 Golgi-to-ER retrograde transport 84/4920 133/10654 5.4966902670265515e-5 1.2431932752564093e-4 4.767132108126079e-5 11014/51807/53407/347688/5861/10381/1780/5048/8655/832/285643/10112/636/7846/11004/10749/81930/54732/51164/29127/23299/1315/3796/5870/11316/55614/89953/56992/8729/10376/1314/10540/3835/3833/378/9493/140735/10959/3831/22820/84617/11258/1783/55850/9585/10382/55860/830/3832/7277/10671/9554/23303/1639/8775/81876/9183/1062/51143/10383/24137/84790/84643/5049/7280/829/22931/1778/55582/5321/23095/5050/1781/10121/6836/547/10972/381/4905/9276/55083/3799/375/22818 84 Human_herpesvirus_2 R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 24/4920 29/10654 5.561982033786143e-5 1.255931426983968e-4 4.815977652344538e-5 2308/4089/4088/3630/56729/2538/3484/5443/3066/2645/5105/4303/23410/4287/2908/4852/6648/4087/25942/2309/6720/114907/3065/10891 24 Human_herpesvirus_2 R-HSA-438066 Unblocking of NMDA receptors, glutamate binding and activation 20/4920 23/10654 5.9873209564969335e-5 1.3497986053294213e-4 5.17591946404515e-5 817/1741/1739/1740/818/2902/2906/801/2891/4747/805/2904/2890/2905/816/815/2903/1742/88/808 20 Human_herpesvirus_2 R-HSA-2559583 Cellular Senescence 117/4920 195/10654 6.359533140045527e-5 1.431406173000601e-4 5.488850738573733e-5 1912/3725/9134/11065/4790/7321/6045/8697/27327/80012/7295/5925/472/79813/3576/2114/1869/1911/4194/1031/5928/1432/4683/23512/57332/192669/8900/51529/4001/29945/8091/51434/1030/6196/4343/6197/29882/4217/3569/7314/996/7014/5601/5606/7027/2146/5594/898/890/5970/9261/6667/51433/5598/84733/119504/6195/7157/7324/64682/6233/2353/8726/5600/26523/5608/6015/1019/9448/246184/1029/8535/5931/7013/1051/50488/8881/6774/7867/3552/10524/5602/10393/51343/7311/25906/57634/648/23466/3456/2113/6416/23523/5595/1017/25913/3159/7290/10111/57690/1027/192670/3490/8550/29855/7316/1026/1871/1021/25842/23135/23112/5609/5599/10919/4193/23043 117 Human_herpesvirus_2 R-HSA-2426168 Activation of gene expression by SREBF (SREBP) 32/4920 42/10654 7.106029692925344e-5 1.5943015336691477e-4 6.113487083994475e-5 79718/5469/1387/4801/6309/10499/23054/85441/31/5465/2222/6667/3156/6604/10654/6319/6721/9453/4800/32/1595/4047/4802/6720/2194/4597/1717/6256/10498/2224/4520/8648 32 Human_herpesvirus_2 R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 32/4920 42/10654 7.106029692925344e-5 1.5943015336691477e-4 6.113487083994475e-5 2788/9495/2782/8826/2787/5567/10681/112/5573/111/2792/2785/2783/2784/2791/5568/5566/2786/5577/54331/5575/59345/51764/94235/114/3708/55970/2778/2793/5576/5906/2790 32 Human_herpesvirus_2 R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 27/4920 34/10654 7.538415672807259e-5 1.6859076584552977e-4 6.464758690317305e-5 5431/5435/5433/5439/11198/904/51497/5438/1025/7936/6829/25920/2963/5434/5436/2962/5432/6917/5440/5430/6749/5441/7469/9150/5437/6827/8178 27 Human_herpesvirus_2 R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 27/4920 34/10654 7.538415672807259e-5 1.6859076584552977e-4 6.464758690317305e-5 5431/5435/5433/5439/11198/904/51497/5438/1025/7936/6829/25920/2963/5434/5436/2962/5432/6917/5440/5430/6749/5441/7469/9150/5437/6827/8178 27 Human_herpesvirus_2 R-HSA-2132295 MHC class II antigen presentation 78/4920 123/10654 8.205804573904934e-5 1.8322370659436854e-4 7.025871455874283e-5 162/51807/1174/347688/1785/10381/1780/1509/8655/832/285643/3113/10112/7846/5476/6456/11004/163/1759/3127/81930/51164/161/10053/29127/22872/3796/89953/56992/10376/10540/3835/1213/1211/9493/6396/1175/7879/140735/8907/3831/1173/84617/11258/6712/1783/10382/10802/821/55860/830/3123/3832/7277/160/10671/3122/1639/26052/1062/51143/9871/10383/24137/84790/84643/8905/1075/7280/829/1778/164/10120/130340/1781/10121/3799/375 78 Human_herpesvirus_2 R-HSA-382556 ABC-family proteins mediated transport 67/4920 103/10654 8.242844909920789e-5 1.8341782313625177e-4 7.033315022517924e-5 5689/1965/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/4363/10057/5696/5691/7314/5718/5700/122706/5707/10956/79139/91445/23198/9861/8894/5698/5692/5713/5710/5719/6233/1968/5243/5706/335/340273/5714/5688/5687/23456/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/5824/1244/7316/10213/7415/5715/5701/5825/5685/5686/5716/5693/5721 67 Human_herpesvirus_2 R-HSA-110312 Translesion synthesis by REV1 15/4920 16/10654 8.319308406537134e-5 1.8341782313625177e-4 7.033315022517924e-5 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/7311/5983/7316/5981/5980 15 Human_herpesvirus_2 R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 15/4920 16/10654 8.319308406537134e-5 1.8341782313625177e-4 7.033315022517924e-5 1869/5928/7027/5934/890/983/286826/91750/1874/55957/4605/1875/5933/3065/132660 15 Human_herpesvirus_2 R-HSA-1433559 Regulation of KIT signaling 15/4920 16/10654 8.319308406537134e-5 1.8341782313625177e-4 7.033315022517924e-5 5777/5578/2534/2885/3815/9306/6714/7525/3932/10019/8651/4067/6654/867/4254 15 Human_herpesvirus_2 R-HSA-193639 p75NTR signals via NF-kB 15/4920 16/10654 8.319308406537134e-5 1.8341782313625177e-4 7.033315022517924e-5 4790/8878/4792/3654/3551/7314/5970/6233/7189/7311/4804/5584/4615/7316/4803 15 Human_herpesvirus_2 R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 15/4920 16/10654 8.319308406537134e-5 1.8341782313625177e-4 7.033315022517924e-5 5295/5291/2534/2885/9846/5290/5170/6464/2205/2206/6850/4067/6654/5296/2207 15 Human_herpesvirus_2 R-HSA-5654219 Phospholipase C-mediated cascade: FGFR1 15/4920 16/10654 8.319308406537134e-5 1.8341782313625177e-4 7.033315022517924e-5 2250/5335/2253/8074/2260/2249/2248/2247/2246/2251/8822/2254/26281/2255/27006 15 Human_herpesvirus_2 R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 15/4920 16/10654 8.319308406537134e-5 1.8341782313625177e-4 7.033315022517924e-5 8454/4790/3551/7314/8945/8517/6233/79155/7311/6416/1147/5604/6500/7316/23291 15 Human_herpesvirus_2 R-HSA-195721 Signaling by WNT 187/4920 331/10654 8.41008996059153e-5 1.8512776642811544e-4 7.098884276566832e-5 2788/8454/27123/9070/5689/857/5579/5682/5331/1459/5526/1452/5578/1212/5929/27327/1460/143471/5705/6657/8452/5530/5709/9978/5695/1457/9559/4609/5881/5711/1387/5683/324/5699/8724/8312/2782/5702/192669/57216/1855/163/79412/5518/4343/25776/3845/6659/5696/5691/4920/7314/5879/5515/2787/5718/51176/8945/161/6662/79971/51701/5700/122706/5707/1856/1454/8322/23198/10681/9101/7471/7534/5528/7091/51699/2792/9861/81847/5519/2932/5698/5692/5713/2785/2783/2784/5710/5719/6233/7474/1857/7514/4040/1213/1211/7855/331/8607/1175/26523/801/2791/4221/805/123169/1173/144165/6597/864/4772/10023/409/79577/5706/160/5714/6934/10524/5688/5687/4919/23236/5708/51339/5529/2786/208/57680/5704/7311/387/5694/5516/57154/27161/815/5684/8295/5720/54331/7015/6885/1487/1499/5525/59345/207/8085/5690/5532/57690/5717/9491/6500/51764/94235/3708/10197/192670/64750/7316/10213/55970/5216/5715/5701/2793/1455/5685/5686/2033/54894/5534/3065/23112/23513/5527/1488/5716/23072/808/9736/5693/5721/6259/2790 187 Human_herpesvirus_2 R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 30/4920 39/10654 8.815219773765612e-5 1.9374109392891455e-4 7.429169767198977e-5 5982/25898/6117/10714/55666/7314/6118/9636/11201/51455/5985/5984/6233/5424/7706/5425/5111/6119/5427/9246/51426/7311/5983/57804/7316/5426/9100/7415/5981/5980 30 Human_herpesvirus_2 R-HSA-111932 CaMK IV-mediated phosphorylation of CREB 12/4920 12/10654 9.338773413726714e-5 2.0207546799408654e-4 7.748758547141665e-5 817/814/818/801/805/3838/10645/84254/816/815/1385/808 12 Human_herpesvirus_2 R-HSA-170968 Frs2-mediated activation 12/4920 12/10654 9.338773413726714e-5 2.0207546799408654e-4 7.748758547141665e-5 5605/1399/5594/4914/673/2889/7529/5595/5604/10818/4803/5906 12 Human_herpesvirus_2 R-HSA-1839130 Signaling by activated point mutants of FGFR3 12/4920 12/10654 9.338773413726714e-5 2.0207546799408654e-4 7.748758547141665e-5 2250/2253/8823/8074/2249/2247/2246/8822/8817/2254/26281/2261 12 Human_herpesvirus_2 R-HSA-190873 Gap junction degradation 12/4920 12/10654 9.338773413726714e-5 2.0207546799408654e-4 7.748758547141665e-5 71/1212/1785/2697/1759/4646/1601/1213/1211/1173/8218/60 12 Human_herpesvirus_2 R-HSA-2029481 FCGR activation 12/4920 12/10654 9.338773413726714e-5 2.0207546799408654e-4 7.748758547141665e-5 2268/2534/6714/7525/2214/2209/6850/4067/919/3055/917/2212 12 Human_herpesvirus_2 R-HSA-2033514 FGFR3 mutant receptor activation 12/4920 12/10654 9.338773413726714e-5 2.0207546799408654e-4 7.748758547141665e-5 2250/2253/8823/8074/2249/2247/2246/8822/8817/2254/26281/2261 12 Human_herpesvirus_2 R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 12/4920 12/10654 9.338773413726714e-5 2.0207546799408654e-4 7.748758547141665e-5 7159/23368/8797/7157/8626/7161/8795/8793/3486/355/8794/124446 12 Human_herpesvirus_2 R-HSA-8984722 Interleukin-35 Signalling 12/4920 12/10654 9.338773413726714e-5 2.0207546799408654e-4 7.748758547141665e-5 3717/3572/10148/3592/7297/6775/3595/821/6774/6772/3716/9466 12 Human_herpesvirus_2 R-HSA-9020558 Interleukin-2 signaling 12/4920 12/10654 9.338773413726714e-5 2.0207546799408654e-4 7.748758547141665e-5 6776/3558/3718/3932/6777/6464/6850/3716/2185/3561/3560/3559 12 Human_herpesvirus_2 R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 12/4920 12/10654 9.338773413726714e-5 2.0207546799408654e-4 7.748758547141665e-5 5295/5291/3717/2056/8660/5290/5294/2057/4067/5293/2549/23533 12 Human_herpesvirus_2 R-HSA-9012852 Signaling by NOTCH3 36/4920 49/10654 9.461349245096246e-5 2.0441186640640036e-4 7.838349764455954e-5 4904/182/11060/22938/1387/9794/9787/388585/7314/23286/2648/55534/3280/84441/4854/3714/102/10320/8850/5087/6233/5663/10460/10046/6772/26508/23493/7311/1956/4851/23462/7316/1950/2033/54567/3516 36 Human_herpesvirus_2 R-HSA-983231 Factors involved in megakaryocyte development and platelet production 102/4920 168/10654 9.599040286753112e-5 2.070671248298052e-4 7.940167944601552e-5 3443/11311/51807/347688/55619/10381/832/285643/3043/10112/3717/7846/11004/10749/2626/7465/81930/5879/3445/25/30846/5868/23348/23186/5567/29127/3444/5573/91768/50808/3796/23414/3451/55614/3448/89953/56992/10376/3066/7157/3439/55669/3835/3833/3452/9493/81704/3660/3446/9732/3831/84617/85440/9585/10019/10382/5568/830/3832/7277/23303/3659/5566/80005/2627/1062/3440/4602/998/7975/5577/10383/24137/60/25942/84790/84643/3456/1020/7280/829/55582/11216/1017/23468/3441/2624/5575/23095/2625/25970/3449/81928/3705/5576/547/3065/23028/55083/3799/51317/10938 102 Human_herpesvirus_2 R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 28/4920 36/10654 1.0823136696603512e-4 2.3311371346530638e-4 8.93894690731626e-5 71/51517/10094/8976/2885/5879/25/10093/10006/5594/10810/23191/10109/5747/10092/10163/55845/998/695/10097/60/5595/4690/10458/10552/10096/7454/10095 28 Human_herpesvirus_2 R-HSA-157118 Signaling by NOTCH 137/4920 235/10654 1.0892645000425668e-4 2.3425043011668102e-4 8.982535290188519e-5 8454/5689/3725/79718/5682/892/4904/182/27327/3091/5705/5709/9978/1869/5695/9759/9612/4609/11060/22938/5711/1387/4088/5683/408/5699/6400/4853/5702/192669/83737/6868/9794/4343/9787/388585/5696/5691/7314/5718/23286/79885/2648/9734/7027/5700/5707/51564/55534/3280/84441/10013/7534/4854/3714/7091/8650/102/10320/9861/5870/8850/5087/5698/5692/5713/595/5710/3066/7157/5719/6233/2324/26523/5663/10959/1999/4192/409/5706/10460/10046/1024/5714/6772/10014/5688/5687/5708/59/26508/4855/5704/23493/7311/1956/5694/4851/27161/5684/8841/2208/5720/5584/23462/207/5690/57690/5717/9491/6500/51548/10197/192670/488/7316/10213/1950/9611/1871/5715/5701/5685/5686/2033/55294/3065/861/2683/23112/5716/1385/1840/54567/3516/5693/5721 137 Human_herpesvirus_2 R-HSA-400685 Sema4D in semaphorin signaling 21/4920 25/10654 1.1022193734816045e-4 2.3667287160647948e-4 9.075425903707107e-5 2909/388/2064/23365/79784/9475/4628/6093/10507/5879/389/10627/4233/387/4629/4627/3985/10398/4637/103910/6237 21 Human_herpesvirus_2 R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 19/4920 22/10654 1.1365671050415063e-4 2.4330182676729495e-4 9.32961892115191e-5 3725/7531/356/7001/4001/826/823/2801/993/351/6648/1020/4000/994/2309/10018/995/8851/5052 19 Human_herpesvirus_2 R-HSA-8863678 Neurodegenerative Diseases 19/4920 22/10654 1.1365671050415063e-4 2.4330182676729495e-4 9.32961892115191e-5 3725/7531/356/7001/4001/826/823/2801/993/351/6648/1020/4000/994/2309/10018/995/8851/5052 19 Human_herpesvirus_2 R-HSA-1592230 Mitochondrial biogenesis 62/4920 95/10654 1.3035523362181102e-4 2.786218733901304e-4 1.0683996648794474e-4 5563/55735/79718/53632/3313/5469/10989/1432/1387/25813/2101/10499/23054/1386/85441/3054/7019/814/23408/51422/5465/54927/2747/4208/6604/55902/6742/5600/6300/801/133522/64216/805/4899/5442/3418/23082/23410/8834/4209/2553/5571/2551/4580/6648/10651/5564/51106/23373/5565/2746/8841/200186/9611/23409/54205/6256/10498/1385/808/8648/10891 62 Human_herpesvirus_2 R-HSA-75893 TNF signaling 32/4920 43/10654 1.5484925386321185e-4 3.304709686105131e-4 1.2672195036944484e-4 7124/7375/9530/10616/6868/1540/3551/7314/257397/90268/8737/55072/23118/841/8517/7128/10454/6233/8772/331/8717/330/27005/7311/1147/7186/56957/6885/7316/7132/329/9099 32 Human_herpesvirus_2 R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 14/4920 15/10654 1.697084412444329e-4 3.578190026238043e-4 1.3720879047980465e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/5527 14 Human_herpesvirus_2 R-HSA-5099900 WNT5A-dependent internalization of FZD4 14/4920 15/10654 1.697084412444329e-4 3.578190026238043e-4 1.3720879047980465e-4 5579/5578/1212/163/161/1856/8322/7474/1213/1211/1175/1173/409/160 14 Human_herpesvirus_2 R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 14/4920 15/10654 1.697084412444329e-4 3.578190026238043e-4 1.3720879047980465e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/5527 14 Human_herpesvirus_2 R-HSA-5358508 Mismatch Repair 14/4920 15/10654 1.697084412444329e-4 3.578190026238043e-4 1.3720879047980465e-4 4436/9156/6117/10714/6118/3978/5424/2956/4292/5425/5111/6119/57804/5395 14 Human_herpesvirus_2 R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 14/4920 15/10654 1.697084412444329e-4 3.578190026238043e-4 1.3720879047980465e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/5527 14 Human_herpesvirus_2 R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 14/4920 15/10654 1.697084412444329e-4 3.578190026238043e-4 1.3720879047980465e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/5527 14 Human_herpesvirus_2 R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 14/4920 15/10654 1.697084412444329e-4 3.578190026238043e-4 1.3720879047980465e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/5527 14 Human_herpesvirus_2 R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 14/4920 15/10654 1.697084412444329e-4 3.578190026238043e-4 1.3720879047980465e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/5527 14 Human_herpesvirus_2 R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF) 39/4920 55/10654 1.741389395041622e-4 3.6605783078953014e-4 1.4036804037794012e-4 79718/3638/5469/1387/4801/6309/10499/23054/85441/31/8720/5465/2222/6667/3156/6604/10654/6319/6721/10802/9453/4800/32/1595/5901/4047/9871/3837/4802/6720/2194/22937/4597/1717/6256/10498/2224/4520/8648 39 Human_herpesvirus_2 R-HSA-71406 Pyruvate metabolism and Citric Acid (TCA) cycle 39/4920 55/10654 1.741389395041622e-4 3.6605783078953014e-4 1.4036804037794012e-4 5161/5160/5165/8050/6389/50/3939/160287/3948/4191/3421/25874/54704/1737/5467/23539/5162/1431/4199/2271/2739/5164/4967/3418/1743/728294/7416/92483/3419/3945/4200/3420/8803/5163/682/6256/1738/10873/6566 39 Human_herpesvirus_2 R-HSA-933542 TRAF6 mediated NF-kB activation 20/4920 24/10654 2.0244299548274146e-4 4.1807982454479965e-4 1.6031632369762995e-4 4790/4792/177/64135/3551/4214/8517/5970/23586/4791/351/7706/7189/1147/7186/57506/4793/3146/6288/6285 20 Human_herpesvirus_2 R-HSA-1059683 Interleukin-6 signaling 11/4920 11/10654 2.024700864581244e-4 4.1807982454479965e-4 1.6031632369762995e-4 9021/3717/3569/3572/3570/7297/5781/6774/6772/3716/867 11 Human_herpesvirus_2 R-HSA-174414 Processive synthesis on the C-strand of the telomere 11/4920 11/10654 2.024700864581244e-4 4.1807982454479965e-4 1.6031632369762995e-4 2237/1763/6117/10714/6118/3978/5424/5425/5111/6119/57804 11 Human_herpesvirus_2 R-HSA-1839122 Signaling by activated point mutants of FGFR1 11/4920 11/10654 2.024700864581244e-4 4.1807982454479965e-4 1.6031632369762995e-4 2250/2253/8074/2260/2249/2247/2246/2251/8822/2254/26281 11 Human_herpesvirus_2 R-HSA-196025 Formation of annular gap junctions 11/4920 11/10654 2.024700864581244e-4 4.1807982454479965e-4 1.6031632369762995e-4 71/1212/1785/2697/1759/1601/1213/1211/1173/8218/60 11 Human_herpesvirus_2 R-HSA-2514853 Condensation of Prometaphase Chromosomes 11/4920 11/10654 2.024700864581244e-4 4.1807982454479965e-4 1.6031632369762995e-4 1459/1460/1457/64151/10051/983/23397/9133/891/10592/9918 11 Human_herpesvirus_2 R-HSA-2586552 Signaling by Leptin 11/4920 11/10654 2.024700864581244e-4 4.1807982454479965e-4 1.6031632369762995e-4 3953/9021/6776/3717/8660/3667/3952/6777/5781/6774/25970 11 Human_herpesvirus_2 R-HSA-5655291 Signaling by FGFR4 in disease 11/4920 11/10654 2.024700864581244e-4 4.1807982454479965e-4 1.6031632369762995e-4 5295/4893/5335/2264/2885/3845/3265/5290/6654/2549/10818 11 Human_herpesvirus_2 R-HSA-8851805 MET activates RAS signaling 11/4920 11/10654 2.024700864581244e-4 4.1807982454479965e-4 1.6031632369762995e-4 4893/3082/2885/3845/3265/57610/6464/4233/6654/10048/200958 11 Human_herpesvirus_2 R-HSA-8875555 MET activates RAP1 and RAC1 11/4920 11/10654 2.024700864581244e-4 4.1807982454479965e-4 1.6031632369762995e-4 5908/3082/2885/1399/5879/85440/4233/2889/2549/1398/5906 11 Human_herpesvirus_2 R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 11/4920 11/10654 2.024700864581244e-4 4.1807982454479965e-4 1.6031632369762995e-4 627/4893/2885/3845/3265/4909/5781/6654/4915/10817/10818 11 Human_herpesvirus_2 R-HSA-9614399 Regulation of localization of FOXO transcription factors 11/4920 11/10654 2.024700864581244e-4 4.1807982454479965e-4 1.6031632369762995e-4 2308/10971/2810/7534/10000/7532/4303/208/7529/2309/207 11 Human_herpesvirus_2 R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 16/4920 18/10654 2.0744664767828014e-4 4.2772504675934043e-4 1.6401486755433358e-4 4893/5578/2885/6196/6197/3845/3265/1839/5594/5598/6195/6654/1956/5595/4314/1385 16 Human_herpesvirus_2 R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 18/4920 21/10654 2.1440128097373844e-4 4.4141440200475555e-4 1.6926416918979352e-4 2237/5982/6117/10714/6118/328/3978/5985/5984/5424/5425/5111/6119/5427/5983/57804/5426/5981 18 Human_herpesvirus_2 R-HSA-1251985 Nuclear signaling by ERBB4 25/4920 32/10654 2.2635137828686582e-4 4.646509231695193e-4 1.781744141477104e-4 2670/51741/6776/10413/145957/6868/9542/6387/1839/2069/23118/348/6714/2099/1447/3925/5663/5241/3084/10718/685/9611/2066/6285/11033 25 Human_herpesvirus_2 R-HSA-73863 RNA Polymerase I Transcription Termination 25/4920 32/10654 2.2635137828686582e-4 4.646509231695193e-4 1.781744141477104e-4 5435/2965/2967/30834/404672/2068/9533/5434/9015/4331/9013/2966/2071/10849/6908/5440/902/9014/25885/5441/51082/7343/5437/2968/1022 25 Human_herpesvirus_2 R-HSA-75153 Apoptotic execution phase 37/4920 52/10654 2.2762884694519134e-4 4.6658914454358397e-4 1.789176418926525e-4 2339/10059/660/836/324/4001/3836/6709/6093/840/5062/2934/22985/63967/841/100506658/7082/5339/10134/999/5588/5580/839/5747/118/1829/1832/3148/4000/3837/51765/1499/3146/329/4137/7431/6304 37 Human_herpesvirus_2 R-HSA-977606 Regulation of Complement cascade 34/4920 47/10654 2.442434985720392e-4 4.999135935685013e-4 1.916961900149892e-4 5199/7448/717/1380/975/1369/720/729/727/629/27202/3078/712/3075/716/1191/721/728/4179/930/1378/1361/966/81494/715/3426/10878/10877/1370/1991/1604/710/719/718 34 Human_herpesvirus_2 R-HSA-73887 Death Receptor Signalling 86/4920 141/10654 2.645236624158323e-4 5.406323027476865e-4 2.073101311288121e-4 7124/7984/4790/7531/29/356/7375/9530/8878/1894/4792/836/23365/10616/3654/6868/8997/26084/8874/1540/3551/7314/5879/257397/9181/90268/8737/55072/2245/23118/841/8517/6453/9828/5970/8797/7128/10454/3066/6233/7410/7409/26574/8772/331/8717/5663/84894/445328/572/7074/330/10451/27005/843/8837/11108/7189/6654/7311/387/6655/8795/5924/1147/4804/8841/7186/56957/6885/5584/10018/57580/8793/835/9459/355/23421/4615/7316/7132/329/9099/4803/3065/5599 86 Human_herpesvirus_2 R-HSA-933541 TRAF6 mediated IRF7 activation 23/4920 29/10654 2.7331502483868514e-4 5.569738497440454e-4 2.135764386236565e-4 3443/1387/64135/3445/29110/3444/23586/3451/3448/3661/3439/3452/3446/3665/7706/3440/7189/3456/3441/7186/57506/3449/2033 23 Human_herpesvirus_2 R-HSA-9619483 Activation of AMPK downstream of NMDARs 23/4920 29/10654 2.7331502483868514e-4 5.569738497440454e-4 2.135764386236565e-4 5563/51807/347688/53632/10381/7846/51422/10376/801/805/84617/10382/7277/10645/5571/5562/10383/84790/5564/5565/7280/4137/808 23 Human_herpesvirus_2 R-HSA-112315 Transmission across Chemical Synapses 154/4920 272/10654 3.0061250439285665e-4 6.117114914970921e-4 2.3456606064926086e-4 2788/5563/6507/4893/1312/5579/5331/23426/2900/2770/51807/817/2550/5578/347688/53632/10381/9463/10497/107/9568/8500/81539/7846/9495/2782/1134/1741/10550/1739/163/6196/1740/8874/6197/8825/3845/3265/3312/777/814/2773/5879/2787/5923/818/161/5567/4646/5594/51422/10681/112/5573/2902/111/2901/2792/3359/6714/54407/2752/2567/2785/10376/6195/2783/2784/2906/2771/6844/196883/3759/115/1175/801/2891/2744/2791/4747/805/5170/1173/84617/3838/8573/6857/9254/2904/2890/10382/2556/5568/2036/7277/5864/160/113/80852/6582/10645/55327/5566/84254/2905/5571/27330/23236/3084/816/2786/5577/22999/10369/5562/10383/773/84790/5564/5565/5924/7280/109/5595/64130/815/27165/54331/28964/5575/59345/7915/51764/94235/114/108/55970/774/346562/2793/5576/2903/6572/4137/2066/4905/9647/1742/88/1385/808/8536/4193/2790 154 Human_herpesvirus_2 R-HSA-180024 DARPP-32 events 21/4920 26/10654 0.00032279282118457577 6.558925249033471e-4 2.515076599253436e-4 5530/5499/5518/5515/5567/5573/5528/5519/801/805/5568/5566/5577/1020/5516/5533/5575/5532/5576/5534/808 21 Human_herpesvirus_2 R-HSA-977444 GABA B receptor activation 29/4920 39/10654 3.240791635181144e-4 6.566003312957455e-4 2.5177907440663926e-4 2788/2770/2550/107/9568/2782/2773/2787/112/111/2792/2785/2783/2784/2771/196883/3759/115/113/2786/109/54331/94235/114/108/55970/346562/2793/2790 29 Human_herpesvirus_2 R-HSA-991365 Activation of GABAB receptors 29/4920 39/10654 3.240791635181144e-4 6.566003312957455e-4 2.5177907440663926e-4 2788/2770/2550/107/9568/2782/2773/2787/112/111/2792/2785/2783/2784/2771/196883/3759/115/113/2786/109/54331/94235/114/108/55970/346562/2793/2790 29 Human_herpesvirus_2 R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 13/4920 14/10654 3.447796509501953e-4 6.836990245471295e-4 2.6217030264589174e-4 5861/2801/5594/983/8548/8615/9133/891/81876/5347/5595/26003/64689 13 Human_herpesvirus_2 R-HSA-170670 Adenylate cyclase inhibitory pathway 13/4920 14/10654 3.447796509501953e-4 6.836990245471295e-4 2.6217030264589174e-4 2770/107/2773/112/111/2771/196883/115/113/109/114/108/346562 13 Human_herpesvirus_2 R-HSA-177504 Retrograde neurotrophin signalling 13/4920 14/10654 3.447796509501953e-4 6.836990245471295e-4 2.6217030264589174e-4 1785/6456/163/1759/161/4914/1213/1211/1175/1173/160/26052/4803 13 Human_herpesvirus_2 R-HSA-3371568 Attenuation phase 13/4920 14/10654 3.447796509501953e-4 6.836990245471295e-4 2.6217030264589174e-4 3305/1387/3306/3312/3303/3337/3297/3326/3304/10728/3320/2033/2288 13 Human_herpesvirus_2 R-HSA-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase 13/4920 14/10654 3.447796509501953e-4 6.836990245471295e-4 2.6217030264589174e-4 107/5567/5573/801/805/5568/5566/5577/5575/114/5576/1385/808 13 Human_herpesvirus_2 R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 13/4920 14/10654 3.447796509501953e-4 6.836990245471295e-4 2.6217030264589174e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/5527 13 Human_herpesvirus_2 R-HSA-4839744 truncated APC mutants destabilize the destruction complex 13/4920 14/10654 3.447796509501953e-4 6.836990245471295e-4 2.6217030264589174e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/5527 13 Human_herpesvirus_2 R-HSA-4839748 AMER1 mutants destabilize the destruction complex 13/4920 14/10654 3.447796509501953e-4 6.836990245471295e-4 2.6217030264589174e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/5527 13 Human_herpesvirus_2 R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 13/4920 14/10654 3.447796509501953e-4 6.836990245471295e-4 2.6217030264589174e-4 4436/9156/6117/10714/6118/3978/5424/4292/5425/5111/6119/57804/5395 13 Human_herpesvirus_2 R-HSA-5467337 APC truncation mutants have impaired AXIN binding 13/4920 14/10654 3.447796509501953e-4 6.836990245471295e-4 2.6217030264589174e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/5527 13 Human_herpesvirus_2 R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 13/4920 14/10654 3.447796509501953e-4 6.836990245471295e-4 2.6217030264589174e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/5527 13 Human_herpesvirus_2 R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 13/4920 14/10654 3.447796509501953e-4 6.836990245471295e-4 2.6217030264589174e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/5527 13 Human_herpesvirus_2 R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 13/4920 14/10654 3.447796509501953e-4 6.836990245471295e-4 2.6217030264589174e-4 79370/7159/23368/332/64065/7157/604/5875/8626/7161/10397/9540/5876 13 Human_herpesvirus_2 R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 13/4920 14/10654 3.447796509501953e-4 6.836990245471295e-4 2.6217030264589174e-4 79718/9612/4204/814/801/805/5566/25942/8841/9611/2874/3065/808 13 Human_herpesvirus_2 R-HSA-9005895 Pervasive developmental disorders 13/4920 14/10654 3.447796509501953e-4 6.836990245471295e-4 2.6217030264589174e-4 79718/9612/4204/814/801/805/5566/25942/8841/9611/2874/3065/808 13 Human_herpesvirus_2 R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 36/4920 51/10654 3.5595482396090364e-4 7.048610375463438e-4 2.7028505951025213e-4 51807/347688/10381/1780/5048/8655/832/636/7846/51164/23299/5870/10376/10540/140735/84617/11258/1783/10382/55860/830/7277/10671/1639/51143/10383/84790/5049/7280/829/22931/1778/5321/5050/1781/10121 36 Human_herpesvirus_2 R-HSA-428930 Thromboxane signalling through TP receptor 19/4920 23/10654 3.6912833996526176e-4 7.299147965414781e-4 2.7989214002718327e-4 2788/2782/2776/2787/10681/2792/2785/2783/2784/2791/2786/54331/59345/51764/94235/55970/2767/2793/2790 19 Human_herpesvirus_2 R-HSA-166658 Complement cascade 40/4920 58/10654 3.7038421638357883e-4 7.313651663427509e-4 2.804482968682729e-4 5199/10584/7448/717/1380/975/1369/720/729/5648/727/629/3004/27202/3078/1401/712/3075/716/1191/721/728/4179/930/1378/1361/966/81494/715/3426/10878/10877/1370/1991/1604/710/1675/719/4153/718 40 Human_herpesvirus_2 R-HSA-399719 Trafficking of AMPA receptors 24/4920 31/10654 3.877941642112419e-4 7.625166150221048e-4 2.923935892190026e-4 5579/23426/817/5578/9463/9495/1739/163/818/161/4646/1175/2891/1173/2890/2036/160/80852/816/10369/815/4905/1742/4193 24 Human_herpesvirus_2 R-HSA-399721 Glutamate binding, activation of AMPA receptors and synaptic plasticity 24/4920 31/10654 3.877941642112419e-4 7.625166150221048e-4 2.923935892190026e-4 5579/23426/817/5578/9463/9495/1739/163/818/161/4646/1175/2891/1173/2890/2036/160/80852/816/10369/815/4905/1742/4193 24 Human_herpesvirus_2 R-HSA-70268 Pyruvate metabolism 24/4920 31/10654 3.877941642112419e-4 7.625166150221048e-4 2.923935892190026e-4 5161/5160/5165/8050/3939/160287/3948/25874/54704/1737/5467/23539/5162/4199/2739/5164/7416/92483/3945/5163/682/6256/1738/6566 24 Human_herpesvirus_2 R-HSA-190241 FGFR2 ligand binding and activation 17/4920 20/10654 4.0167152679462803e-4 7.856873550585283e-4 3.012786098344732e-4 2250/2252/2253/8823/8074/2249/2248/2247/2246/2251/2263/8822/8817/2254/26281/2255/27006 17 Human_herpesvirus_2 R-HSA-196299 Beta-catenin phosphorylation cascade 15/4920 17/10654 4.0238416684068915e-4 7.856873550585283e-4 3.012786098344732e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/10023/5529/5516/1499/5525/5527 15 Human_herpesvirus_2 R-HSA-450604 KSRP (KHSRP) binds and destabilizes mRNA 15/4920 17/10654 4.0238416684068915e-4 7.856873550585283e-4 3.012786098344732e-4 5393/23404/1432/11340/7534/5600/8570/23016/5073/51010/56915/167227/22894/207/54512 15 Human_herpesvirus_2 R-HSA-9034015 Signaling by NTRK3 (TRKC) 15/4920 17/10654 4.0238416684068915e-4 7.856873550585283e-4 3.012786098344732e-4 5295/4893/5335/2885/3845/3265/5290/3667/6714/25920/4908/6464/6654/4916/581 15 Human_herpesvirus_2 R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 15/4920 17/10654 4.0238416684068915e-4 7.856873550585283e-4 3.012786098344732e-4 2308/857/2290/57060/4089/1647/4088/5934/4303/901/9314/4087/2309/1027/1026 15 Human_herpesvirus_2 R-HSA-9609736 Assembly and cell surface presentation of NMDA receptors 30/4920 41/10654 4.1003698015924236e-4 7.995150030960157e-4 3.065809410368181e-4 51807/817/347688/10381/7846/1741/1739/1740/8825/818/2902/10376/2906/4747/84617/8573/2904/10382/7277/55327/2905/816/10383/84790/7280/64130/815/2903/1742/88 30 Human_herpesvirus_2 R-HSA-110056 MAPK3 (ERK1) activation 10/4920 10/10654 4.389188595234784e-4 8.417621963463968e-4 3.227809925839567e-4 3717/3569/3572/983/3570/7297/5781/3716/5595/5604 10 Human_herpesvirus_2 R-HSA-1250342 PI3K events in ERBB4 signaling 10/4920 10/10654 4.389188595234784e-4 8.417621963463968e-4 3.227809925839567e-4 5295/145957/9542/1839/5290/2069/3084/10718/685/2066 10 Human_herpesvirus_2 R-HSA-174437 Removal of the Flap Intermediate from the C-strand 10/4920 10/10654 4.389188595234784e-4 8.417621963463968e-4 3.227809925839567e-4 2237/1763/6117/10714/6118/5424/5425/5111/6119/57804 10 Human_herpesvirus_2 R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 10/4920 10/10654 4.389188595234784e-4 8.417621963463968e-4 3.227809925839567e-4 5563/53632/1432/51422/5600/6300/5571/5564/5565/10891 10 Human_herpesvirus_2 R-HSA-2465910 MASTL Facilitates Mitotic Progression 10/4920 10/10654 4.389188595234784e-4 8.417621963463968e-4 3.227809925839567e-4 5518/55844/84930/5515/983/5519/2029/891/5516/10776 10 Human_herpesvirus_2 R-HSA-390450 Folding of actin by CCT/TriC 10/4920 10/10654 4.389188595234784e-4 8.417621963463968e-4 3.227809925839567e-4 10576/10574/10693/10575/60/22948/10694/7203/908/6950 10 Human_herpesvirus_2 R-HSA-442729 CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde 10/4920 10/10654 4.389188595234784e-4 8.417621963463968e-4 3.227809925839567e-4 814/818/801/805/3838/10645/84254/816/1385/808 10 Human_herpesvirus_2 R-HSA-450341 Activation of the AP-1 family of transcription factors 10/4920 10/10654 4.389188595234784e-4 8.417621963463968e-4 3.227809925839567e-4 3725/1432/1386/5601/5594/2353/5600/5602/5595/5599 10 Human_herpesvirus_2 R-HSA-74749 Signal attenuation 10/4920 10/10654 4.389188595234784e-4 8.417621963463968e-4 3.227809925839567e-4 3643/3630/2885/8660/3667/5594/6464/6654/5595/2887 10 Human_herpesvirus_2 R-HSA-8853334 Signaling by FGFR3 fusions in cancer 10/4920 10/10654 4.389188595234784e-4 8.417621963463968e-4 3.227809925839567e-4 5295/4893/2885/3845/3265/5290/6654/2549/10818/2261 10 Human_herpesvirus_2 R-HSA-9020958 Interleukin-21 signaling 10/4920 10/10654 4.389188595234784e-4 8.417621963463968e-4 3.227809925839567e-4 6776/50615/3718/6777/59067/6775/6774/6772/3716/3561 10 Human_herpesvirus_2 R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 10/4920 10/10654 4.389188595234784e-4 8.417621963463968e-4 3.227809925839567e-4 2308/7295/1387/10628/23411/8850/4303/23410/2309/2033 10 Human_herpesvirus_2 R-HSA-5357905 Regulation of TNFR1 signaling 25/4920 33/10654 5.240067651766246e-4 0.0010035697281084465 3.8482748972579526e-4 7124/7375/10616/1540/3551/7314/90268/8737/55072/841/8517/7128/6233/331/8717/330/27005/7311/1147/7186/56957/7316/7132/329/9099 25 Human_herpesvirus_2 R-HSA-5689896 Ovarian tumor domain proteases 28/4920 38/10654 5.293485337703991e-4 0.0010124152285226212 3.8821937334326074e-4 7321/324/64135/7314/8737/55611/8517/80124/983/2099/23586/7128/7157/6233/55593/10318/7706/79155/79589/7189/7311/387/56957/57506/7316/7415/5728/78990 28 Human_herpesvirus_2 R-HSA-389357 CD28 dependent PI3K/Akt signaling 18/4920 22/10654 6.677518480868815e-4 0.0012736411271411909 4.883887028887273e-4 5295/941/2534/2475/5290/57761/9020/10000/3932/253260/5170/64223/8503/208/79109/207/942/5296 18 Human_herpesvirus_2 R-HSA-9613829 Chaperone Mediated Autophagy 18/4920 22/10654 6.677518480868815e-4 0.0012736411271411909 4.883887028887273e-4 2670/1915/5116/3043/3920/3312/11315/7314/10013/123/6233/3326/7311/1080/7316/3320/200894/7431 18 Human_herpesvirus_2 R-HSA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 12/4920 13/10654 6.972049875216945e-4 0.0013190364628788815 5.057959368934057e-4 5925/5422/1869/28227/5518/5558/5515/7027/5557/5519/23649/5516 12 Human_herpesvirus_2 R-HSA-190239 FGFR3 ligand binding and activation 12/4920 13/10654 6.972049875216945e-4 0.0013190364628788815 5.057959368934057e-4 2250/2253/8823/8074/2249/2247/2246/8822/8817/2254/26281/2261 12 Human_herpesvirus_2 R-HSA-190372 FGFR3c ligand binding and activation 12/4920 13/10654 6.972049875216945e-4 0.0013190364628788815 5.057959368934057e-4 2250/2253/8823/8074/2249/2247/2246/8822/8817/2254/26281/2261 12 Human_herpesvirus_2 R-HSA-209543 p75NTR recruits signalling complexes 12/4920 13/10654 6.972049875216945e-4 0.0013190364628788815 5.057959368934057e-4 8878/3654/3551/7314/6233/7189/7311/4804/5584/4615/7316/4803 12 Human_herpesvirus_2 R-HSA-5140745 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 12/4920 13/10654 6.972049875216945e-4 0.0013190364628788815 5.057959368934057e-4 1212/163/4920/161/7474/1213/1211/7855/1175/1173/160/4919 12 Human_herpesvirus_2 R-HSA-879415 Advanced glycosylation endproduct receptor signaling 12/4920 13/10654 6.972049875216945e-4 0.0013190364628788815 5.057959368934057e-4 177/5594/351/1650/830/3958/829/5595/5589/3146/6288/6285 12 Human_herpesvirus_2 R-HSA-110320 Translesion Synthesis by POLH 16/4920 19/10654 7.468422088807685e-4 0.001411037911515622 5.410746878744114e-4 5982/25898/6117/55666/7314/6118/5985/5984/6233/5111/6119/7311/5983/7316/7415/5981 16 Human_herpesvirus_2 R-HSA-190242 FGFR1 ligand binding and activation 14/4920 16/10654 7.753159414978675e-4 0.0014628602669771085 5.609464181641543e-4 2250/2253/8074/2260/2249/2248/2247/2246/2251/8822/2254/26281/2255/27006 14 Human_herpesvirus_2 R-HSA-3000170 Syndecan interactions 21/4920 27/10654 8.1933157778615e-4 0.0015438280065957067 5.919941980179025e-4 5578/7448/3688/3690/87/6382/7040/3655/2247/2335/3685/9672/3691/8573/1277/3371/6383/1281/3673/7057/1278 21 Human_herpesvirus_2 R-HSA-2173789 TGF-beta receptor signaling activates SMADs 24/4920 32/10654 8.721225219843747e-4 0.0016366910600242957 6.276033388063089e-4 4738/4089/23327/4088/5499/9110/7040/7314/4092/11171/9958/9040/6233/7514/5500/5501/4087/7048/7311/57154/10273/64750/7316/867 24 Human_herpesvirus_2 R-HSA-8941326 RUNX2 regulates bone development 24/4920 32/10654 8.721225219843747e-4 0.0016366910600242957 6.276033388063089e-4 5925/9759/10413/4089/25/5594/3280/100526737/10013/2737/865/6714/7525/10432/1277/23493/367/860/5595/8841/23462/4086/4094/23314 24 Human_herpesvirus_2 R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 24/4920 32/10654 8.721225219843747e-4 0.0016366910600242957 6.276033388063089e-4 5295/5777/84876/2534/30011/2885/6786/80228/5336/7409/801/805/930/6850/4067/695/6654/5293/4690/640/3708/10768/974/808 24 Human_herpesvirus_2 R-HSA-5693532 DNA Double-Strand Break Repair 97/4920 166/10654 9.362846073433116e-4 0.0017547502681133015 6.728741629607397e-4 2237/83990/151987/9156/1763/7486/5982/11200/472/6613/27434/64421/4683/165918/84126/8900/8924/2067/672/6117/7334/10714/348654/83695/55183/7314/6118/25/5888/322/51588/51720/63967/5531/116028/890/7517/9656/5985/7157/5984/6233/7158/6047/5884/5810/5424/8467/80010/3838/7515/51567/580/11073/5591/5425/641/5111/6119/3364/22976/10524/5427/144715/142/1111/7329/79728/51426/7311/3980/5536/5983/2547/79840/1017/5883/10111/57804/7520/675/51548/545/7336/2072/7316/8314/5426/10635/7341/5932/2138/79184/7156/5599/5981/2139 97 Human_herpesvirus_2 R-HSA-8940973 RUNX2 regulates osteoblast differentiation 19/4920 24/10654 0.0010025326489988423 0.0018763980061475658 7.195210399513221e-4 5925/10413/25/5594/3280/10013/2737/865/6714/7525/1277/23493/367/860/5595/8841/23462/4094/23314 19 Human_herpesvirus_2 R-HSA-416572 Sema4D induced cell migration and growth-cone collapse 17/4920 21/10654 0.001197570071533411 0.0022354641335290337 8.572080512028625e-4 388/2064/23365/79784/9475/4628/6093/10507/389/10627/387/4629/4627/3985/10398/4637/103910 17 Human_herpesvirus_2 R-HSA-9008059 Interleukin-37 signaling 17/4920 21/10654 0.001197570071533411 0.0022354641335290337 8.572080512028625e-4 834/5777/26469/5783/27178/59307/4088/29110/8809/5781/5782/6774/5780/5771/5778/25930/5784 17 Human_herpesvirus_2 R-HSA-8875878 MET promotes cell motility 29/4920 41/10654 0.0012622963574093077 0.00235314900182827 9.023353315281335e-4 3675/5908/3082/3688/3910/2885/1399/5879/3918/284217/6714/2335/64759/84951/85440/5747/1277/3912/4233/2889/3913/2549/3915/1281/3673/3914/1398/5906/1278 29 Human_herpesvirus_2 R-HSA-1368082 RORA activates gene expression 15/4920 18/10654 0.0013770717626527275 0.002563697430470503 9.830719470225236e-4 79718/5469/1387/10499/23054/85441/5465/6604/1374/6095/6720/2033/6256/10498/8648 15 Human_herpesvirus_2 R-HSA-2173788 Downregulation of TGF-beta receptor signaling 20/4920 26/10654 0.0013997752508093837 0.002576543762181858 9.87997983994547e-4 23327/4088/5499/9110/7040/7314/4092/11171/9958/6233/7514/5500/5501/4087/7048/7311/57154/10273/64750/7316 20 Human_herpesvirus_2 R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 20/4920 26/10654 0.0013997752508093837 0.002576543762181858 9.87997983994547e-4 83990/9156/1763/7486/472/4683/672/5888/116028/7517/80010/580/641/10524/79728/10111/675/10635/5932/7156 20 Human_herpesvirus_2 R-HSA-190373 FGFR1c ligand binding and activation 11/4920 12/10654 0.0014023759619875543 0.002576543762181858 9.87997983994547e-4 2250/2253/8074/2260/2249/2247/2246/2251/8822/2254/26281 11 Human_herpesvirus_2 R-HSA-210990 PECAM1 interactions 11/4920 12/10654 0.0014023759619875543 0.002576543762181858 9.87997983994547e-4 5777/5335/5175/2534/3690/6714/7525/3685/3932/5781/4067 11 Human_herpesvirus_2 R-HSA-2197563 NOTCH2 intracellular domain regulates transcription 11/4920 12/10654 0.0014023759619875543 0.002576543762181858 9.87997983994547e-4 4853/9794/388585/55534/3280/84441/10046/2208/2033/1385/3516 11 Human_herpesvirus_2 R-HSA-3371511 HSF1 activation 11/4920 12/10654 0.0014023759619875543 0.002576543762181858 9.87997983994547e-4 7531/1915/6117/6118/10013/3297/6119/3326/10728/7415/3320 11 Human_herpesvirus_2 R-HSA-389359 CD28 dependent Vav1 pathway 11/4920 12/10654 0.0014023759619875543 0.002576543762181858 9.87997983994547e-4 941/2534/2885/5062/5879/7409/3932/5063/998/5058/942 11 Human_herpesvirus_2 R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 11/4920 12/10654 0.0014023759619875543 0.002576543762181858 9.87997983994547e-4 834/55367/472/7157/839/317/843/8626/7161/835/58484 11 Human_herpesvirus_2 R-HSA-8866427 VLDLR internalisation and degradation 11/4920 12/10654 0.0014023759619875543 0.002576543762181858 9.87997983994547e-4 163/10062/161/1213/1211/1175/29116/1173/160/255738/7376 11 Human_herpesvirus_2 R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 11/4920 12/10654 0.0014023759619875543 0.002576543762181858 9.87997983994547e-4 64135/3551/8737/841/8517/23586/8772/7706/843/1147/57506 11 Human_herpesvirus_2 R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 23/4920 31/10654 0.0014384415288475384 0.0026393422547661255 0.001012078608970469 857/5526/1452/324/8312/1855/5518/5515/1856/7471/5528/5519/2932/1857/4040/7855/10023/5529/5516/1499/5525/1455/5527 23 Human_herpesvirus_2 R-HSA-937039 IRAK1 recruits IKK complex 13/4920 15/10654 0.0014827425140376436 0.002713515711964315 0.0010405210624825569 3654/7334/3551/7314/8517/6233/57162/7189/7311/1147/246330/7316/57161 13 Human_herpesvirus_2 R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 13/4920 15/10654 0.0014827425140376436 0.002713515711964315 0.0010405210624825569 3654/7334/3551/7314/8517/6233/57162/7189/7311/1147/246330/7316/57161 13 Human_herpesvirus_2 R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 24/4920 33/10654 0.001800431206805045 0.0032906053388081762 0.0012618110697685486 4790/4792/177/3654/7334/3551/7314/257397/23118/8517/5970/10454/6233/4791/351/7189/7311/1147/6885/7316/4793/3146/6288/6285 24 Human_herpesvirus_2 R-HSA-9024446 NR1H2 and NR1H3-mediated signaling 32/4920 47/10654 0.0019719345209629527 0.003599358969163147 0.0013802053190024098 79718/27327/9612/55818/192669/4343/1071/10062/348/26523/29116/5105/6319/19/5346/27161/8841/347/8204/57690/6720/192670/9611/2874/2194/2033/221656/23028/6256/23112/7376/8648 32 Human_herpesvirus_2 R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 16/4920 20/10654 0.0021275249372253364 0.003873257362959 0.0014852340263978119 7321/7334/3551/7314/8737/8517/7323/6233/330/7098/7189/7311/1147/7316/7322/329 16 Human_herpesvirus_2 R-HSA-622312 Inflammasomes 16/4920 20/10654 0.0021275249372253364 0.003873257362959 0.0014852340263978119 834/4790/7295/29108/10628/5970/24145/598/4791/351/3326/4210/114548/596/58484/22861 16 Human_herpesvirus_2 R-HSA-8951664 Neddylation 130/4920 234/10654 0.002269168191827883 0.004125760348777968 0.0015820584796065896 8454/5689/5682/80344/93611/7321/9021/4738/9817/5929/3091/143471/5705/8452/5709/9978/5695/54620/7704/10980/5711/5683/23113/5699/10987/7428/5702/26094/25793/1154/92591/84961/5696/5691/9820/7314/51514/5718/54165/8945/64410/23363/23038/5700/122706/5707/23198/332/7323/9306/4008/1643/26118/9861/6502/90864/55832/5698/5692/10920/5713/10238/5710/9040/5719/6233/83987/8835/11275/54939/10537/8451/899/9655/5931/5706/26263/8450/84078/5714/26272/5688/5687/26270/1161/5708/1642/5704/2873/7311/2034/8533/51667/5694/51138/9318/5684/8065/5720/11091/25879/54850/5690/5717/9491/6500/26259/10197/7316/10213/114907/64708/7322/5715/5701/23291/5685/5686/55294/8453/123879/80176/8139/26043/5716/80204/8883/23014/5693/5721 130 Human_herpesvirus_2 R-HSA-186797 Signaling by PDGF 38/4920 58/10654 0.0022903027244163096 0.004158785751209901 0.0015947223557271047 5295/4893/5335/5291/6696/6776/2885/8440/9564/3845/3265/1399/56034/5290/5340/5921/6778/6714/5154/6777/5781/80310/5782/6774/6772/2889/5159/2886/6654/4690/1299/1281/1398/5155/5296/7059/7057/5156 38 Human_herpesvirus_2 R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 22/4920 30/10654 0.002349729589990813 0.004261167650242407 0.001633981580168141 11065/7321/8239/3093/7328/7332/7314/90268/29089/7324/6233/7874/7317/7327/7311/997/7319/7320/7316/54926/7322/27338 22 Human_herpesvirus_2 R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 19/4920 25/10654 0.002368016482095135 0.004283233946942105 0.0016424430924364465 51807/10381/10576/7846/10574/10693/10575/10376/84617/10382/7277/10383/84790/22948/7280/10694/7203/908/6950 19 Human_herpesvirus_2 R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 19/4920 25/10654 0.002368016482095135 0.004283233946942105 0.0016424430924364465 3107/811/567/3106/3309/3133/6892/22872/10134/6396/3135/10802/6890/821/2923/9871/3105/6891/3134 19 Human_herpesvirus_2 R-HSA-450513 Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA 14/4920 17/10654 0.002515664223231364 0.004532728330146602 0.0017381138709584713 5393/23404/11340/9261/23016/3842/7538/51010/56915/167227/7529/22894/54464/54512 14 Human_herpesvirus_2 R-HSA-4655427 SUMOylation of DNA methylation proteins 14/4920 17/10654 0.002515664223231364 0.004532728330146602 0.0017381138709584713 1912/6045/80012/1911/57332/1788/84733/7703/6015/8535/1786/7329/648/7341 14 Human_herpesvirus_2 R-HSA-9022699 MECP2 regulates neuronal receptors and channels 14/4920 17/10654 0.002515664223231364 0.004532728330146602 0.0017381138709584713 5770/4988/4204/3066/2891/2904/4233/6515/25942/4986/2289/2903/3065/1385 14 Human_herpesvirus_2 R-HSA-2025928 Calcineurin activates NFAT 10/4920 11/10654 0.0028034065901770128 0.004993345071562109 0.0019147413432305832 5530/4773/5478/801/805/4772/4775/5532/5534/808 10 Human_herpesvirus_2 R-HSA-2468052 Establishment of Sister Chromatid Cohesion 10/4920 11/10654 0.0028034065901770128 0.004993345071562109 0.0019147413432305832 10274/157570/113130/23047/5885/8243/23244/10735/9126/114799 10 Human_herpesvirus_2 R-HSA-3371378 Regulation by c-FLIP 10/4920 11/10654 0.0028034065901770128 0.004993345071562109 0.0019147413432305832 356/8737/841/8797/8772/8717/8837/8795/7186/355 10 Human_herpesvirus_2 R-HSA-4755510 SUMOylation of immune response proteins 10/4920 11/10654 0.0028034065901770128 0.004993345071562109 0.0019147413432305832 4792/6612/51588/8517/5970/4791/10210/7329/7341/10401 10 Human_herpesvirus_2 R-HSA-5218900 CASP8 activity is inhibited 10/4920 11/10654 0.0028034065901770128 0.004993345071562109 0.0019147413432305832 356/8737/841/8797/8772/8717/8837/8795/7186/355 10 Human_herpesvirus_2 R-HSA-68689 CDC6 association with the ORC:origin complex 10/4920 11/10654 0.0028034065901770128 0.004993345071562109 0.0019147413432305832 1869/84515/4998/990/5001/23594/4999/5000/23595/1871 10 Human_herpesvirus_2 R-HSA-69416 Dimerization of procaspase-8 10/4920 11/10654 0.0028034065901770128 0.004993345071562109 0.0019147413432305832 356/8737/841/8797/8772/8717/8837/8795/7186/355 10 Human_herpesvirus_2 R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 10/4920 11/10654 0.0028034065901770128 0.004993345071562109 0.0019147413432305832 7314/257397/23118/10454/6233/7098/7189/7311/6885/7316 10 Human_herpesvirus_2 R-HSA-9020956 Interleukin-27 signaling 10/4920 11/10654 0.0028034065901770128 0.004993345071562109 0.0019147413432305832 3717/3572/10148/7297/821/6774/6772/3716/246778/9466 10 Human_herpesvirus_6A R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 227/786 244/10654 4.757107498150359e-247 5.261360892954297e-244 3.194773246126241e-244 10450/7536/2962/10212/10921/51690/10898/22938/29894/1993/8449/27238/1665/55749/23165/11017/51503/988/22827/3178/10286/9883/23451/53981/7919/6637/199746/9972/23450/348995/51213/10236/23524/2963/56949/79023/9984/5437/10250/6635/53938/6629/57122/5441/6634/5434/23636/5440/4670/10914/5094/23020/5903/6633/10569/220988/55599/23225/51593/6432/26097/8683/51691/6431/8021/9775/23658/3192/10189/3183/5438/85313/10084/8563/6430/79622/57187/6632/51340/9716/10762/5431/84248/6434/10283/9092/51362/6627/55706/7175/55110/54883/9295/5093/24148/22794/129401/23511/6936/154007/81608/5435/10946/8896/6427/10594/4686/9785/9631/8189/23398/83443/79228/6625/3312/10465/84844/5433/6631/10713/10482/27339/8175/51645/10949/5356/51692/84271/53371/11051/11338/55660/6426/3181/84950/5439/1655/10421/9343/55954/11193/3188/29107/80145/51729/3185/9129/1660/55696/4116/23350/5430/25949/84991/3190/10907/10291/5432/55746/1477/23283/10978/79869/85437/22916/9416/65109/8086/9939/6626/56339/11066/84321/4904/84324/11157/5436/5546/56259/2521/5725/1479/26121/9879/22826/11100/10081/51639/51585/3191/7307/10285/10523/285755/6429/1478/6428/8480/10772/9410/6638/24144/57819/57794/10992/57721/11325/55339/9128/57703/9877/23279/4927/10262/10181/6628/9688/27316/6636/27258/8233/3184/3187/1994/8106/25804/79902 227 Human_herpesvirus_6A R-HSA-72172 mRNA Splicing 185/786 191/10654 4.58690474679029e-209 2.53655832497503e-206 1.5402343307643183e-206 10450/7536/2962/10921/51690/10898/22938/29894/1993/8449/27238/1665/55749/11017/51503/988/22827/3178/10286/23451/53981/6637/199746/23450/10236/23524/2963/56949/5437/10250/6635/53938/6629/5441/6634/5434/5440/4670/10914/5094/23020/6633/10569/220988/55599/51593/6432/8683/51691/6431/9775/23658/3192/10189/3183/5438/85313/10084/6430/79622/6632/51340/9716/5431/6434/10283/9092/51362/6627/55110/54883/9295/5093/24148/22794/6936/154007/81608/5435/10946/8896/6427/10594/4686/9785/8189/23398/83443/6625/3312/10465/84844/5433/6631/10713/27339/8175/51645/10949/5356/51692/11051/11338/55660/6426/3181/84950/5439/1655/10421/9343/55954/11193/3188/51729/3185/9129/1660/55696/4116/23350/5430/25949/84991/3190/10907/10291/5432/1477/23283/10978/79869/85437/22916/9416/65109/9939/6626/11066/4904/11157/5436/5546/56259/2521/5725/1479/26121/9879/22826/11100/10081/51639/51585/3191/7307/10285/10523/285755/6429/1478/6428/10772/9410/6638/24144/57819/57794/10992/11325/55339/9128/57703/10262/10181/6628/27316/6636/27258/8233/3184/3187/1994/8106/25804 185 Human_herpesvirus_6A R-HSA-72163 mRNA Splicing - Major Pathway 177/786 183/10654 2.8210502156886705e-199 1.0400271795172233e-196 6.315193114418848e-197 10450/7536/2962/10921/51690/10898/22938/29894/1993/8449/27238/1665/55749/11017/51503/988/22827/3178/10286/23451/53981/6637/199746/23450/10236/23524/2963/56949/5437/10250/6635/53938/6629/5441/6634/5434/5440/4670/10914/5094/23020/6633/10569/220988/51593/6432/8683/51691/6431/9775/23658/3192/10189/3183/5438/85313/10084/6430/6632/51340/9716/5431/6434/10283/9092/51362/6627/55110/54883/9295/5093/24148/22794/6936/81608/5435/10946/8896/6427/10594/4686/9785/8189/23398/83443/6625/3312/10465/84844/5433/6631/10713/27339/8175/51645/10949/5356/51692/11051/11338/55660/6426/3181/84950/5439/1655/10421/9343/11193/3188/51729/3185/9129/1660/55696/4116/23350/5430/25949/84991/3190/10907/10291/5432/1477/23283/10978/79869/22916/9416/65109/9939/6626/4904/11157/5436/5546/56259/2521/5725/1479/26121/9879/22826/11100/51639/51585/3191/7307/10285/10523/285755/6429/1478/6428/10772/9410/6638/24144/57819/57794/10992/11325/55339/9128/57703/10262/10181/6628/27316/6636/27258/3184/3187/1994/8106/25804 177 Human_herpesvirus_6A R-HSA-72202 Transport of Mature Transcript to Cytoplasm 73/786 84/10654 8.054841008128594e-72 2.2271635387475564e-69 1.3523654113647483e-69 10212/10921/10898/29894/23165/9883/53981/7919/199746/9972/348995/51213/79023/9984/10250/57122/23636/5903/10569/23225/6432/26097/8683/6431/8021/9775/10189/8563/6430/57187/10762/84248/51362/55706/7175/55110/9295/22794/129401/23511/81608/6427/4686/9785/9631/8189/79228/10482/51692/84271/53371/11338/6426/29107/80145/4116/55746/22916/65109/8086/9939/84321/84324/7307/6429/6428/8480/55339/9877/23279/4927/9688/79902 73 Human_herpesvirus_6A R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 66/786 75/10654 9.505780569274117e-66 2.1026786619234345e-63 1.2767764217256602e-63 10212/10921/23165/9883/7919/199746/9972/348995/51213/79023/9984/10250/57122/23636/5903/10569/23225/6432/26097/8683/6431/8021/9775/10189/8563/6430/57187/10762/84248/51362/55706/7175/55110/9295/22794/129401/23511/6427/4686/9785/9631/79228/10482/84271/53371/11338/6426/29107/80145/4116/55746/22916/65109/8086/9939/84321/84324/7307/6429/6428/8480/9877/23279/4927/9688/79902 66 Human_herpesvirus_6A R-HSA-73856 RNA Polymerase II Transcription Termination 62/786 67/10654 4.446888852214298e-65 8.197098450915023e-63 4.977394890724074e-63 10212/10921/10898/29894/53981/7919/6637/199746/51213/9984/10250/6635/6634/10914/10569/6432/26097/8683/6431/9775/10189/8563/6430/57187/84248/51362/55110/9295/22794/81608/6427/4686/9785/8189/79228/51692/84271/11051/11338/6426/80145/4116/1477/23283/10978/79869/22916/65109/9939/84321/84324/1479/51585/7307/6429/1478/6428/55339/9877/6628/6636/8106 62 Human_herpesvirus_6A R-HSA-72187 mRNA 3'-end processing 57/786 58/10654 2.3189367713846167e-64 3.6639200987876946e-62 2.224784451343437e-62 10212/10921/10898/29894/53981/7919/199746/51213/9984/10250/10914/10569/6432/26097/8683/6431/9775/10189/8563/6430/57187/84248/51362/55110/9295/22794/81608/6427/4686/9785/8189/79228/51692/84271/11051/11338/6426/80145/4116/1477/23283/10978/79869/22916/65109/9939/84321/84324/1479/51585/7307/6429/1478/6428/55339/9877/8106 57 Human_herpesvirus_6A R-HSA-611105 Respiratory electron transport 74/786 100/10654 7.289072592511198e-63 1.0077142859146732e-60 6.118984623713348e-61 6390/51300/9377/4710/4706/7384/4728/137682/51295/4708/4724/28976/4722/4725/374291/51103/4729/10975/4716/126328/54539/4695/7386/4717/4698/4519/4723/1329/29796/4541/25915/1340/4700/4702/1327/4713/4535/4697/10128/4720/4537/27089/4714/1537/4711/4709/4731/79133/84987/4718/4712/91942/4707/4701/4540/55967/4715/4538/4696/4694/7388/1345/4705/7381/4719/9997/55471/29078/55863/51079/4704/7385/4536/4726 74 Human_herpesvirus_6A R-HSA-6799198 Complex I biogenesis 54/786 55/10654 6.701569983877626e-61 8.235484891298504e-59 5.000703683875935e-59 51300/4710/4706/4728/137682/51295/4708/4724/28976/4722/4725/374291/51103/4729/4716/126328/54539/4695/4717/4698/4723/4541/25915/4700/4702/4713/4535/4720/4537/4714/4711/4709/4731/79133/4718/4712/91942/4707/4701/4540/55967/4715/4538/4696/4694/4705/4719/55471/29078/55863/51079/4704/4536/4726 54 Human_herpesvirus_6A R-HSA-72165 mRNA Splicing - Minor Pathway 51/786 52/10654 1.9090030339468872e-57 2.1113573555452573e-55 1.2820462480611727e-55 2962/23451/6637/23450/2963/5437/6635/5441/6634/5434/5440/23020/6633/55599/6432/6431/5438/79622/6632/5431/24148/154007/5435/6427/10594/4686/83443/5433/6426/5439/9343/55954/5430/10907/5432/85437/22916/9416/11066/4904/5436/10081/51639/9410/57819/10992/11325/10262/6628/6636/8233 51 Human_herpesvirus_6A R-HSA-163200 Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 74/786 123/10654 1.2889057284456829e-52 1.2959361233281139e-50 7.869108657878905e-51 6390/51300/9377/4710/4706/7384/4728/137682/51295/4708/4724/28976/4722/4725/374291/51103/4729/10975/4716/126328/54539/4695/7386/4717/4698/4519/4723/1329/29796/4541/25915/1340/4700/4702/1327/4713/4535/4697/10128/4720/4537/27089/4714/1537/4711/4709/4731/79133/84987/4718/4712/91942/4707/4701/4540/55967/4715/4538/4696/4694/7388/1345/4705/7381/4719/9997/55471/29078/55863/51079/4704/7385/4536/4726 74 Human_herpesvirus_6A R-HSA-1428517 The citric acid (TCA) cycle and respiratory electron transport 75/786 174/10654 1.2679541632744839e-39 1.168631087151316e-37 7.096094352360707e-38 6390/51300/9377/4710/4706/2739/7384/4728/137682/51295/4708/4724/28976/4722/4725/374291/51103/4729/10975/4716/126328/54539/4695/7386/4717/4698/4519/4723/1329/29796/4541/25915/1340/4700/4702/1327/4713/4535/4697/10128/4720/4537/27089/4714/1537/4711/4709/4731/79133/84987/4718/4712/91942/4707/4701/4540/55967/4715/4538/4696/4694/7388/1345/4705/7381/4719/9997/55471/29078/55863/51079/4704/7385/4536/4726 75 Human_herpesvirus_6A R-HSA-168325 Viral Messenger RNA Synthesis 38/786 43/10654 2.776455120578403e-38 2.3621225871997798e-36 1.4343144671490048e-36 2962/23165/9883/9972/348995/2963/79023/5437/57122/5441/5434/23636/5440/5903/23225/8021/5438/10762/5431/55706/7175/129401/23511/5435/9631/5433/53371/5439/5430/5432/55746/8086/5436/8480/23279/4927/9688/79902 38 Human_herpesvirus_6A R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 35/786 41/10654 3.4250772843682547e-34 2.705811054650921e-32 1.643006998065373e-32 10898/29894/23165/9883/53981/9972/348995/79023/57122/23636/5903/23225/8021/10189/10762/55706/7175/129401/23511/81608/4686/9631/8189/10482/51692/53371/55746/22916/8086/8480/55339/23279/4927/9688/79902 35 Human_herpesvirus_6A R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 35/786 42/10654 1.913717245056785e-33 1.4110475153552028e-31 8.568081419973535e-32 10898/29894/23165/9883/53981/9972/348995/79023/57122/23636/5903/23225/8021/10189/10762/55706/7175/129401/23511/81608/4686/9631/8189/10482/51692/53371/55746/22916/8086/8480/55339/23279/4927/9688/79902 35 Human_herpesvirus_6A R-HSA-159227 Transport of the SLBP independent Mature mRNA 28/786 34/10654 1.1176310442945563e-26 7.72562459368612e-25 4.691109251710046e-25 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10189/10762/55706/7175/129401/23511/4686/9631/10482/53371/55746/22916/8086/8480/23279/4927/9688/79902 28 Human_herpesvirus_6A R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 28/786 35/10654 5.203269317244299e-26 3.3851858028659974e-24 2.0555330182054878e-24 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10189/10762/55706/7175/129401/23511/4686/9631/10482/53371/55746/22916/8086/8480/23279/4927/9688/79902 28 Human_herpesvirus_6A R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 39/786 72/10654 9.587934725980196e-26 5.891253226074498e-24 3.577252839283839e-24 4012/6517/5898/8773/79058/7533/2810/4644/55763/10890/7534/6810/808/71/54536/5872/8766/7531/60412/801/10640/9847/4218/4627/11336/7532/207/10971/51552/149371/4641/7529/208/6814/5879/805/55770/23265/6844 39 Human_herpesvirus_6A R-HSA-191859 snRNP Assembly 33/786 53/10654 1.1309120332413098e-24 6.253943543824443e-23 3.797483564252398e-23 23165/9883/6637/9972/348995/79023/6635/57122/6634/23636/5903/6633/23225/8021/6632/10762/55706/7175/129401/23511/4686/9631/53371/55746/22916/8086/8480/23279/4927/6628/9688/6636/79902 33 Human_herpesvirus_6A R-HSA-194441 Metabolism of non-coding RNA 33/786 53/10654 1.1309120332413098e-24 6.253943543824443e-23 3.797483564252398e-23 23165/9883/6637/9972/348995/79023/6635/57122/6634/23636/5903/6633/23225/8021/6632/10762/55706/7175/129401/23511/4686/9631/53371/55746/22916/8086/8480/23279/4927/6628/9688/6636/79902 33 Human_herpesvirus_6A R-HSA-3371556 Cellular response to heat stress 42/786 89/10654 1.6244217388411893e-24 8.555287824563597e-23 5.1948925783492666e-23 23165/6119/6118/9883/9972/348995/815/545/79023/472/57122/23636/5903/23225/23411/8021/3320/6117/10762/55706/7175/129401/23511/9631/3312/7531/53371/816/9531/55746/817/8086/22824/8480/5594/23279/4927/9688/3308/7415/5595/79902 42 Human_herpesvirus_6A R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 27/786 35/10654 2.37432644372333e-24 1.193638657617274e-22 7.247943880839638e-23 23165/9883/9972/348995/79023/9133/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/891/53371/55746/983/8086/8480/23279/4927/9688/79902 27 Human_herpesvirus_6A R-HSA-3371453 Regulation of HSF1-mediated heat shock response 37/786 69/10654 2.8236771557044418e-24 1.357820406177875e-22 8.244878834505418e-23 23165/6119/6118/9883/9972/348995/545/79023/472/57122/23636/5903/23225/23411/8021/6117/10762/55706/7175/129401/23511/9631/3312/7531/53371/9531/55746/8086/22824/8480/5594/23279/4927/9688/3308/5595/79902 37 Human_herpesvirus_6A R-HSA-75067 Processing of Capped Intronless Pre-mRNA 24/786 28/10654 7.488978913026343e-24 3.390368449422134e-22 2.0586799949855539e-22 10898/29894/53981/6637/6635/6634/10914/81608/4686/8189/51692/11051/1477/23283/10978/79869/22916/1479/51585/1478/55339/6628/6636/8106 24 Human_herpesvirus_6A R-HSA-4615885 SUMOylation of DNA replication proteins 30/786 45/10654 7.663581486035565e-24 3.390368449422134e-22 2.0586799949855539e-22 7153/23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/332/10762/55706/7175/55143/129401/23511/9631/53371/55746/8086/6790/5111/8480/9212/23279/4927/9688/79902 30 Human_herpesvirus_6A R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 25/786 31/10654 1.6736513145086488e-23 7.119455207102175e-22 4.323034569459586e-22 7514/23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 25 Human_herpesvirus_6A R-HSA-2980766 Nuclear Envelope Breakdown 31/786 52/10654 1.9789308256056718e-022 8.106287011555084e-21 4.922252891759917e-21 23165/9883/9972/348995/79023/9133/57122/23636/5903/5347/23225/8021/7443/10762/55706/7175/129401/23511/9631/891/53371/55746/983/7112/8086/64900/8480/23279/4927/9688/79902 31 Human_herpesvirus_6A R-HSA-77595 Processing of Intronless Pre-mRNAs 19/786 19/10654 2.523642164817955e-22 9.968386551030923e-21 6.052946244939306e-21 10898/29894/53981/10914/81608/4686/8189/51692/11051/1477/23283/10978/79869/22916/1479/51585/1478/55339/8106 19 Human_herpesvirus_6A R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 25/786 33/10654 2.7365005381161673e-22 1.0436446879849935e-20 6.337159140900598e-21 7514/23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 25 Human_herpesvirus_6A R-HSA-3700989 Transcriptional Regulation by TP53 84/786 365/10654 7.422556371164115e-22 2.602827893307184e-20 1.5804741562101297e-20 672/2962/9377/898/1025/1017/7533/2810/6119/6118/5170/1432/11200/2963/545/5437/8812/5518/6917/472/5441/9134/5434/5440/4436/8851/5300/7534/1329/332/5438/580/4343/6117/5431/1340/11073/5934/995/1327/1874/5435/4697/10128/9156/7316/84126/5433/891/7531/7027/84987/1459/890/5439/1111/1020/5430/7157/1107/8900/1457/5432/983/7532/207/10971/5436/1345/6790/641/9997/5933/22974/5111/9212/7529/208/1108/8148/6233/4193/79109/1263 84 Human_herpesvirus_6A R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 24/786 31/10654 7.766123008963569e-22 2.602827893307184e-20 1.5804741562101297e-20 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Human_herpesvirus_6A R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 24/786 31/10654 7.766123008963569e-22 2.602827893307184e-20 1.5804741562101297e-20 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Human_herpesvirus_6A R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 24/786 31/10654 7.766123008963569e-22 2.602827893307184e-20 1.5804741562101297e-20 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Human_herpesvirus_6A R-HSA-165054 Rev-mediated nuclear export of HIV RNA 25/786 34/10654 9.626322285938186e-22 3.131386014190481e-20 1.9014221728880996e-20 7514/23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 25 Human_herpesvirus_6A R-HSA-168253 Host Interactions with Influenza Factors 27/786 42/10654 6.040758990265077e-21 1.9088798409237642e-19 1.1590990182824417e-19 10898/23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/293/53371/55746/8086/8480/23279/4927/9688/8106/79902 27 Human_herpesvirus_6A R-HSA-176033 Interactions of Vpr with host cellular proteins 25/786 36/10654 9.560871988532219e-21 2.8009887365970055e-19 1.7008002416949554e-19 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/293/53371/55746/8086/8480/23279/4927/9688/79902 25 Human_herpesvirus_6A R-HSA-177243 Interactions of Rev with host cellular proteins 25/786 36/10654 9.560871988532219e-21 2.8009887365970055e-19 1.7008002416949554e-19 7514/23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 25 Human_herpesvirus_6A R-HSA-180746 Nuclear import of Rev protein 24/786 33/10654 9.876904224889984e-21 2.8009887365970055e-19 1.7008002416949554e-19 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Human_herpesvirus_6A R-HSA-180910 Vpr-mediated nuclear import of PICs 24/786 33/10654 9.876904224889984e-21 2.8009887365970055e-19 1.7008002416949554e-19 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Human_herpesvirus_6A R-HSA-162599 Late Phase of HIV Life Cycle 48/786 139/10654 1.0711961750033162e-20 2.9618574238841694e-19 1.7984819990845152e-19 2962/7514/1025/23165/9883/9972/348995/2963/79023/5437/8812/6917/57122/5441/5434/23636/5440/5903/23225/8021/5438/10762/5431/55706/7175/129401/23511/5435/4686/9631/27183/7316/5433/53371/5439/5430/5432/55746/22916/8086/5436/8480/23279/4927/9688/8148/6233/79902 48 Human_herpesvirus_6A R-HSA-69620 Cell Cycle Checkpoints 72/786 293/10654 1.4278329521425546e-20 3.851666451389428e-19 2.3387867097996147e-19 701/672/7514/898/1017/7533/9088/2810/6119/6118/348995/81565/4173/11200/545/79023/9133/1062/5518/472/699/57122/9134/64105/5903/5347/10197/11065/7534/54908/332/8318/580/6117/8881/990/11073/55143/995/9156/7316/84126/891/7531/51512/993/5501/7465/1058/890/1111/8655/991/7157/4085/8900/55746/983/7532/10971/140735/641/8924/9212/11004/7529/1063/23279/6233/4193/55388/79902 72 Human_herpesvirus_6A R-HSA-162587 HIV Life Cycle 50/786 152/10654 1.8786564130785388e-20 4.947128554440152e-19 3.0039668961005206e-19 2962/7514/1025/23165/9883/9972/348995/2963/79023/5437/8812/6917/57122/5441/5434/23636/5440/5903/23225/8021/5438/3981/10762/5431/55706/7175/129401/23511/5435/4686/9631/27183/7316/5433/2547/53371/5439/5430/5432/55746/22916/8086/5436/8480/23279/4927/9688/8148/6233/79902 50 Human_herpesvirus_6A R-HSA-168276 NS1 Mediated Effects on Host Pathways 26/786 40/10654 2.1341634494805966e-20 5.489266918896604e-19 3.3331610300333426e-19 10898/23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/8106/79902 26 Human_herpesvirus_6A R-HSA-4085377 SUMOylation of SUMOylation proteins 24/786 34/10654 3.127115701600094e-20 7.860431740840235e-19 4.772966070863302e-19 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Human_herpesvirus_6A R-HSA-6803529 FGFR2 alternative splicing 21/786 26/10654 6.042784508222822e-20 1.485182148020987e-18 9.0182374649033e-19 2962/3178/2963/5437/5441/5434/5440/4670/5438/5431/5435/4686/5433/5439/3185/5430/5432/22916/5436/5725/3187 21 Human_herpesvirus_6A R-HSA-3232142 SUMOylation of ubiquitinylation proteins 25/786 38/10654 7.471722438599451e-20 1.7964619602371727e-18 1.0908372805094849e-18 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/4193/79902 25 Human_herpesvirus_6A R-HSA-168254 Influenza Infection 49/786 155/10654 3.098629610837711e-19 7.291668828907464e-18 4.427605132619171e-18 2962/10898/7514/23165/9883/9972/348995/2963/6202/79023/5437/57122/5441/5434/23636/5440/5903/23225/3921/8021/5438/3320/10762/5431/55706/7175/129401/23511/5435/9631/293/5433/53371/5439/5430/5432/55746/8086/5436/8480/6173/23279/4927/9688/11224/6233/8106/79902/821 49 Human_herpesvirus_6A R-HSA-4570464 SUMOylation of RNA binding proteins 27/786 47/10654 4.183371901932335e-19 9.639186090702422e-18 5.85305103822989e-18 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/3183/10762/55706/7175/129401/23511/9631/53371/3190/55746/8086/6045/8480/23279/4927/9688/79902 27 Human_herpesvirus_6A R-HSA-195258 RHO GTPase Effectors 74/786 327/10654 6.814826926404632e-19 1.538203791959903e-17 9.340192436189379e-18 701/10097/9055/7514/23380/388/1080/10092/7533/2810/5170/9928/1432/2017/8826/348995/81565/79023/1062/29941/5518/699/57122/64105/6280/5903/5347/387/5300/7534/54908/332/808/71/6242/55143/995/10095/1499/7531/5501/1058/801/4659/10093/8655/10109/991/5586/4085/5585/4627/55746/2316/7532/23028/10552/10971/140735/4629/10094/5500/9212/389/11004/7529/5594/1063/23279/5879/5595/805/10096/79902 74 Human_herpesvirus_6A R-HSA-168255 Influenza Life Cycle 46/786 144/10654 2.4779206443444905e-18 5.4811604652900133e-17 3.328238675982705e-17 2962/7514/23165/9883/9972/348995/2963/6202/79023/5437/57122/5441/5434/23636/5440/5903/23225/3921/8021/5438/3320/10762/5431/55706/7175/129401/23511/5435/9631/5433/53371/5439/5430/5432/55746/8086/5436/8480/6173/23279/4927/9688/11224/6233/79902/821 46 Human_herpesvirus_6A R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 34/786 80/10654 2.7334489880111508e-18 5.927832511255555e-17 3.599464302066283e-17 23165/9883/9972/348995/79023/6059/57122/23636/5903/23225/7706/5300/8021/9775/10762/55706/7175/129401/9470/23511/9631/7316/53371/55746/2316/8086/4734/8480/23279/4927/9688/6233/5595/79902 34 Human_herpesvirus_6A R-HSA-168273 Influenza Viral RNA Transcription and Replication 44/786 134/10654 4.186426429776843e-18 8.904206983333055e-17 5.406761259509364e-17 2962/23165/9883/9972/348995/2963/6202/79023/5437/57122/5441/5434/23636/5440/5903/23225/3921/8021/5438/3320/10762/5431/55706/7175/129401/23511/5435/9631/5433/53371/5439/5430/5432/55746/8086/5436/8480/6173/23279/4927/9688/11224/6233/79902 44 Human_herpesvirus_6A R-HSA-1169408 ISG15 antiviral mechanism 32/786 72/10654 5.3870031056127966e-18 1.1241557424165573e-16 6.826033726675202e-17 23165/9883/9972/348995/79023/57122/23636/5903/23225/7706/5300/8021/9775/10762/55706/7175/129401/9470/23511/9631/7316/53371/55746/8086/4734/8480/23279/4927/9688/6233/5595/79902 32 Human_herpesvirus_6A R-HSA-6784531 tRNA processing in the nucleus 28/786 57/10654 2.4203502956854774e-17 4.957235975978033e-16 3.010104266369073e-16 10898/29894/23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/10978/8086/1478/8480/23279/4927/9688/79902 28 Human_herpesvirus_6A R-HSA-68886 M Phase 79/786 395/10654 9.423733923654298e-17 1.8950272217384826e-15 1.1506875106777877e-15 701/7514/23165/9883/9972/348995/81565/22995/10112/79023/9133/1062/5518/699/57122/23636/64105/55844/5903/5347/113130/23225/10197/11065/8021/54908/332/7443/440145/3320/10762/8881/9493/55706/7175/55143/129401/23511/64151/9631/7316/84930/891/7531/10142/5501/1459/1058/53371/11190/8655/991/5520/4085/10733/1457/55746/983/7112/7532/8086/140735/64900/4751/8480/9212/11004/5594/9232/1063/23279/4927/9688/5577/6233/9700/5595/79902/5566 79 Human_herpesvirus_6A R-HSA-70171 Glycolysis 30/786 71/10654 3.3304201712689804e-16 6.577579838256236e-15 3.994000130206033e-15 23165/9883/9972/348995/79023/2023/5518/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/5230/5567/55746/8086/8480/23279/4927/9688/5568/79902/5566 30 Human_herpesvirus_6A R-HSA-8851708 Signaling by FGFR2 IIIa TM 16/786 19/10654 5.23745829141106e-16 1.016250679000111e-14 6.170818817950612e-15 2962/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 16 Human_herpesvirus_6A R-HSA-5578749 Transcriptional regulation by small RNAs 36/786 106/10654 1.4464056443596226e-15 2.7581459356236944e-14 1.674785482942721e-14 23165/9883/9972/348995/79023/5437/57122/5441/5434/23636/5440/5903/23225/8021/5438/10762/5431/55706/7175/129401/23511/5435/9631/5433/53371/5439/5430/5432/55746/8086/5436/8480/23279/4927/9688/79902 36 Human_herpesvirus_6A R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13/786 13/10654 1.748560532703377e-15 3.2778100833388735e-14 1.9903329524794907e-14 7533/2810/11200/7534/995/891/7531/7465/1111/983/7532/10971/7529 13 Human_herpesvirus_6A R-HSA-162906 HIV Infection 55/786 233/10654 3.87709632560165e-15 7.146780893525708e-14 4.339627115322548e-14 2962/7514/1025/23165/9883/9972/348995/2963/79023/5437/8812/6917/57122/5441/5434/23636/5440/5903/8065/23225/10197/160/8021/5438/3981/10762/5431/55706/7175/129401/23511/5435/4686/9631/27183/7316/293/5433/2547/53371/5439/5430/5432/55746/22916/8086/5436/8480/23279/4927/9688/8148/5879/6233/79902 55 Human_herpesvirus_6A R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 47/786 182/10654 1.1118694311495863e-14 2.015946870248266e-13 1.2241116429222364e-13 672/7153/23165/9883/9972/348995/79023/57122/23636/5903/23225/8517/8021/332/3183/6117/10762/6294/55706/7175/55143/23512/129401/23511/9631/53371/1655/7157/5970/3190/1107/9759/55746/8086/6045/6790/641/5111/8480/8924/9212/2099/23279/4927/9688/4193/79902 47 Human_herpesvirus_6A R-HSA-4551638 SUMOylation of chromatin organization proteins 28/786 71/10654 2.737749225250736e-14 4.883791359882765e-13 2.9655076497622577e-13 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/23512/129401/23511/9631/53371/1107/9759/55746/8086/6045/8480/23279/4927/9688/79902 28 Human_herpesvirus_6A R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 17/786 25/10654 2.970363783980761e-14 5.214638642988448e-13 3.16640283070965e-13 28227/7514/1017/9088/9133/5518/994/5347/2305/995/891/993/7465/890/5520/8900/983 17 Human_herpesvirus_6A R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 29/786 77/10654 3.914722546288842e-14 6.765129900305405e-13 4.107883198243883e-13 672/23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/6117/10762/55706/7175/129401/23511/9631/53371/55746/8086/6045/641/8480/8924/23279/4927/9688/79902 29 Human_herpesvirus_6A R-HSA-2990846 SUMOylation 47/786 188/10654 4.188084120792322e-14 7.126186211686627e-13 4.3271217312801644e-13 672/7153/23165/9883/9972/348995/79023/57122/23636/5903/23225/8517/8021/332/3183/6117/10762/6294/55706/7175/55143/23512/129401/23511/9631/53371/1655/7157/5970/3190/1107/9759/55746/8086/6045/6790/641/5111/8480/8924/9212/2099/23279/4927/9688/4193/79902 47 Human_herpesvirus_6A R-HSA-5654738 Signaling by FGFR2 28/786 73/10654 6.301171148847503e-14 1.055923528882627e-12 6.411718011107985e-13 2962/3178/2963/5437/5518/5441/5434/5440/4670/6464/5438/5431/3845/5435/4686/7316/5433/5439/3185/5430/5432/22916/5436/5725/5594/6233/5595/3187 28 Human_herpesvirus_6A R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 16/786 23/10654 9.994700526321241e-14 1.6498714600166107e-12 1.0018254416014064e-12 2962/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 16 Human_herpesvirus_6A R-HSA-194315 Signaling by Rho GTPases 80/786 455/10654 1.115207010331967e-13 1.8138514020987581e-12 1.101396397200921e-12 701/10097/9055/7514/23380/388/1080/10092/7533/2810/4650/5170/9928/1432/2017/8826/348995/81565/79023/1062/29941/5518/699/57122/64105/6280/5903/5347/387/5300/7534/54908/332/808/85360/71/6242/55143/995/10095/1499/57584/7531/5501/9824/1058/801/4659/10093/8655/10109/991/5586/4085/5585/4627/55746/2316/7532/23028/10552/10971/140735/4629/10094/5500/9212/389/11004/7529/5594/1063/23279/90627/5879/5595/805/7074/10096/79902 80 Human_herpesvirus_6A R-HSA-70326 Glucose metabolism 31/786 91/10654 1.2592534864902513e-13 2.018455588490171e-12 1.2256349723581698e-12 23165/9883/9972/348995/79023/2023/5518/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/5230/5567/55746/8086/8480/23279/4927/9688/5568/1468/79902/5566 31 Human_herpesvirus_6A R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 31/786 92/10654 1.7683786351632793e-13 2.7940382435579815e-12 1.6965798033596572e-12 672/1017/6119/6118/1432/11200/545/472/8851/5300/580/6117/11073/9156/7316/84126/1459/890/1111/1020/7157/8900/1457/6790/641/22974/9212/8148/6233/4193/1263 31 Human_herpesvirus_6A R-HSA-5663205 Infectious disease 70/786 383/10654 6.360736736726409e-13 9.908415254675222e-12 6.0165308199131935e-12 2962/10898/7514/1025/23165/9883/9972/348995/2963/6202/79023/5437/8812/6917/57122/5441/5434/23636/5440/5903/8065/23225/10197/3921/160/8021/5438/3981/9146/3320/10762/808/5431/55706/7175/129401/23511/5435/4686/9631/27183/7316/1499/293/5433/2547/801/53371/5439/5430/5432/55746/22916/8086/5436/8480/6173/23279/4927/9688/11224/8148/30011/5879/6233/805/8106/79902/6844/821 70 Human_herpesvirus_6A R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 23/786 54/10654 8.094709438625663e-13 1.2434373109888865e-11 7.550328394507562e-12 10450/56949/5437/6917/5441/5434/5440/5438/9716/5431/8450/5435/7316/5433/27339/5439/10987/5430/5432/91603/5436/6233/51138 23 Human_herpesvirus_6A R-HSA-5663202 Diseases of signal transduction 69/786 377/10654 8.77508277288878e-13 1.3294851433993137e-11 8.072823084503305e-12 10014/8454/2962/22938/409/399687/5170/8826/2963/815/5437/5518/8805/5441/5434/5440/6464/1956/10197/4140/5438/3320/808/5431/71/3845/79885/408/2100/5435/4686/7316/1499/55294/2065/5433/10142/801/5439/4763/816/10956/6774/5430/8844/2066/5432/9759/22916/817/207/5436/11140/5245/2099/6934/7529/5594/208/4609/5879/6233/57670/7415/5595/4193/1488/805/79109 69 Human_herpesvirus_6A R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 25/786 65/10654 1.3125523511272083e-12 1.9617336491171517e-11 1.1911926031566984e-11 10450/6119/6118/56949/5437/6917/5441/5434/5440/5438/9716/6117/5431/8450/5435/7316/5433/27339/5439/5430/5432/91603/5436/5111/6233 25 Human_herpesvirus_6A R-HSA-211000 Gene Silencing by RNA 37/786 136/10654 1.4315091658729075e-12 2.1109988499405808e-11 1.2818285583535648e-11 23165/9883/9972/348995/79023/5437/57122/5441/5434/23636/5440/5903/23225/8021/5438/3320/10762/5431/55706/7175/129401/23511/5435/9631/5433/53371/5439/5430/5432/55746/8086/5436/8480/23279/4927/9688/79902 37 Human_herpesvirus_6A R-HSA-2262752 Cellular responses to stress 80/786 479/10654 1.8648169899945384e-12 2.71379946175521e-11 1.647857672599052e-11 898/1017/23165/6119/7014/3091/830/6118/9883/9972/1432/348995/815/545/25913/79023/472/57122/9134/23636/1019/5903/5601/23225/23411/10197/11065/8021/4343/3320/8726/6117/10762/10587/8881/55706/7175/23512/1021/129401/23511/9631/7316/3312/112399/7531/7027/890/53371/816/8655/2146/9531/6774/7157/8453/5970/8900/55746/817/8086/140735/832/6045/10963/9550/22824/8480/5594/829/23279/4927/9688/3308/51382/6233/7415/5595/4193/79902 80 Human_herpesvirus_6A R-HSA-6782135 Dual incision in TC-NER 25/786 66/10654 1.967618246158568e-12 2.826215299027761e-11 1.7161181695819086e-11 10450/6119/6118/56949/5437/6917/5441/5434/5440/5438/9716/6117/5431/8450/5435/7316/5433/27339/5439/5430/5432/91603/5436/5111/6233 25 Human_herpesvirus_6A R-HSA-8953897 Cellular responses to external stimuli 81/786 493/10654 3.2436368825496463e-12 4.599310759102447e-11 2.7927669784975363e-11 898/1017/23165/6119/7014/3091/830/6118/9883/9972/1432/348995/815/545/25913/79023/472/57122/9134/23636/1019/5903/5601/23225/23411/10197/11065/8021/4343/3320/8726/6117/4520/10762/10587/8881/55706/7175/23512/1021/129401/23511/9631/7316/3312/112399/7531/7027/890/53371/816/8655/2146/9531/6774/7157/8453/5970/8900/55746/817/8086/140735/832/6045/10963/9550/22824/8480/5594/829/23279/4927/9688/3308/51382/6233/7415/5595/4193/79902 81 Human_herpesvirus_6A R-HSA-1538133 G0 and Early G1 16/786 27/10654 4.010068270254519e-12 5.6140955783563264e-11 3.408958769383588e-11 7153/898/1017/9134/990/5934/1874/993/7027/890/8900/1859/983/5933/5111/4609 16 Human_herpesvirus_6A R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 27/786 79/10654 4.4543544843547e-12 6.158145074620372e-11 3.739313369760919e-11 10450/6119/6118/56949/5437/6917/5441/5434/5440/5438/9716/6117/5431/8450/5435/7316/5433/27339/5439/10987/5430/5432/91603/5436/5111/6233/51138 27 Human_herpesvirus_6A R-HSA-68877 Mitotic Prometaphase 45/786 200/10654 7.83496723825107e-12 1.0698115759883559e-10 6.496048210531751e-11 701/7514/348995/81565/22995/79023/9133/1062/5518/699/57122/64105/5903/5347/113130/54908/332/440145/3320/55143/64151/891/7531/10142/5501/1459/1058/11190/8655/991/4085/10733/1457/55746/983/7532/140735/4751/9212/11004/1063/23279/5577/79902/5566 45 Human_herpesvirus_6A R-HSA-190236 Signaling by FGFR 28/786 87/10654 9.441769401211019e-12 1.2734874338706568e-10 7.732797019220322e-11 2962/3178/2963/5437/5518/5441/5434/5440/4670/6464/5438/5431/3845/5435/4686/7316/5433/5439/3185/5430/5432/22916/5436/5725/5594/6233/5595/3187 28 Human_herpesvirus_6A R-HSA-5633007 Regulation of TP53 Activity 39/786 160/10654 1.493215517330748e-11 1.9897546532142257e-10 1.2082073558110554e-10 672/1017/6119/6118/5170/1432/11200/545/5518/472/8851/5300/580/6117/11073/9156/7316/84126/1459/890/1111/1020/7157/1107/8900/1457/983/207/6790/641/22974/9212/208/1108/8148/6233/4193/79109/1263 39 Human_herpesvirus_6A R-HSA-72086 mRNA Capping 16/786 29/10654 1.8131248376034005e-11 2.3872810361778104e-10 1.449591035577656e-10 2962/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 16 Human_herpesvirus_6A R-HSA-68875 Mitotic Prophase 36/786 142/10654 2.7218277643244138e-11 3.541578243932708e-10 2.1504967351566264e-10 23165/9883/9972/348995/79023/9133/5518/57122/23636/55844/5903/5347/23225/8021/7443/10762/55706/7175/129401/23511/9631/84930/891/53371/55746/983/7112/8086/64900/8480/5594/23279/4927/9688/5595/79902 36 Human_herpesvirus_6A R-HSA-69275 G2/M Transition 43/786 196/10654 5.544769450148444e-11 7.130831409144394e-10 4.329942361315431e-10 8454/28227/7514/1017/9088/22995/9133/5518/994/5347/23291/10197/440145/3320/2305/995/7316/891/7531/51512/993/10142/7465/890/4659/11190/4218/8655/5520/7157/10733/8900/983/7532/6790/22974/4751/3161/5500/1063/5577/6233/5566 43 Human_herpesvirus_6A R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 23/786 65/10654 7.741070686235458e-11 9.8409473321568e-10 5.975563336743161e-10 672/2962/1025/2963/545/5437/8812/6917/472/5441/5434/5440/4436/5438/5431/5435/5433/5439/1111/5430/7157/5432/5436 23 Human_herpesvirus_6A R-HSA-453274 Mitotic G2-G2/M phases 43/786 198/10654 7.855756079291122e-11 9.873257072381797e-10 5.995182271037961e-10 8454/28227/7514/1017/9088/22995/9133/5518/994/5347/23291/10197/440145/3320/2305/995/7316/891/7531/51512/993/10142/7465/890/4659/11190/4218/8655/5520/7157/10733/8900/983/7532/6790/22974/4751/3161/5500/1063/5577/6233/5566 43 Human_herpesvirus_6A R-HSA-167287 HIV elongation arrest and recovery 17/786 36/10654 1.0863049192977246e-10 1.334948045270315e-9 8.105994602478927e-10 2962/1025/2963/5437/8812/6917/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 17 Human_herpesvirus_6A R-HSA-167290 Pausing and recovery of HIV elongation 17/786 36/10654 1.0863049192977246e-10 1.334948045270315e-9 8.105994602478927e-10 2962/1025/2963/5437/8812/6917/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 17 Human_herpesvirus_6A R-HSA-453279 Mitotic G1-G1/S phases 36/786 149/10654 1.1988795510093108e-10 1.4570997619959314e-9 8.847717218553387e-10 51053/8454/28227/7153/898/1017/6119/6118/4173/5518/9134/1019/10197/8318/6117/990/5934/1021/1874/7316/891/993/7027/7465/890/5520/8900/1859/983/207/5933/5111/208/4609/6233/55388 36 Human_herpesvirus_6A R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 22/786 61/10654 1.30346971798451e-10 1.5669972914031177e-9 9.515030664463586e-10 10097/10092/4644/4650/2209/917/3320/71/10095/2214/2212/10093/10109/4627/10552/4620/10094/4641/5594/5879/5595/10096 22 Human_herpesvirus_6A R-HSA-162909 Host Interactions of HIV factors 33/786 129/10654 1.423878927769142e-10 1.6933441872179258e-9 1.0282227005282543e-9 7514/1025/23165/9883/9972/348995/79023/57122/23636/5903/8065/23225/10197/160/8021/10762/55706/7175/129401/23511/9631/7316/293/53371/55746/8086/8480/23279/4927/9688/5879/6233/79902 33 Human_herpesvirus_6A R-HSA-113418 Formation of the Early Elongation Complex 16/786 33/10654 2.3526013557736597e-10 2.7103928119642372e-9 1.645789106341661e-9 2962/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 16 Human_herpesvirus_6A R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 16/786 33/10654 2.3526013557736597e-10 2.7103928119642372e-9 1.645789106341661e-9 2962/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 16 Human_herpesvirus_6A R-HSA-1839126 FGFR2 mutant receptor activation 16/786 33/10654 2.3526013557736597e-10 2.7103928119642372e-9 1.645789106341661e-9 2962/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 16 Human_herpesvirus_6A R-HSA-69481 G2/M Checkpoints 38/786 168/10654 2.9050552678429164e-10 3.312361985808521e-9 2.011313359613435e-9 672/1017/7533/9088/2810/6119/6118/4173/11200/545/9133/472/10197/7534/8318/580/6117/990/11073/995/9156/7316/84126/891/7531/51512/993/7465/1111/7157/983/7532/10971/641/8924/7529/6233/55388 38 Human_herpesvirus_6A R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 19/786 48/10654 3.7307841124510567e-10 4.2104563554804786e-9 2.5566490480599074e-9 2962/1025/2963/5437/8812/6917/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 19 Human_herpesvirus_6A R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 16/786 34/10654 4.142007233287355e-10 4.581060000015815e-9 2.781684857723508e-9 2962/1025/2963/5437/6917/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 16 Human_herpesvirus_6A R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 16/786 34/10654 4.142007233287355e-10 4.581060000015815e-9 2.781684857723508e-9 2962/1025/2963/5437/6917/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 16 Human_herpesvirus_6A R-HSA-72306 tRNA processing 29/786 107/10654 4.2656833938585655e-10 4.67113448872037e-9 2.83637936975692e-9 10898/29894/23165/55006/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/10978/8086/1478/8480/23279/4927/9688/79902 29 Human_herpesvirus_6A R-HSA-141424 Amplification of signal from the kinetochores 27/786 96/10654 6.929418550479736e-10 7.44071545323358e-9 4.5181083650547485e-9 701/7514/348995/81565/79023/1062/5518/699/57122/64105/5903/5347/54908/332/55143/5501/1058/8655/991/4085/55746/140735/9212/11004/1063/23279/79902 27 Human_herpesvirus_6A R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 27/786 96/10654 6.929418550479736e-10 7.44071545323358e-9 4.5181083650547485e-9 701/7514/348995/81565/79023/1062/5518/699/57122/64105/5903/5347/54908/332/55143/5501/1058/8655/991/4085/55746/140735/9212/11004/1063/23279/79902 27 Human_herpesvirus_6A R-HSA-112382 Formation of RNA Pol II elongation complex 21/786 61/10654 9.312693068482824e-10 9.809370032135241e-9 5.956389150568463e-9 2962/1025/2963/5437/8812/6917/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436/80349/123169 21 Human_herpesvirus_6A R-HSA-75955 RNA Polymerase II Transcription Elongation 21/786 61/10654 9.312693068482824e-10 9.809370032135241e-9 5.956389150568463e-9 2962/1025/2963/5437/8812/6917/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436/80349/123169 21 Human_herpesvirus_6A R-HSA-69206 G1/S Transition 32/786 131/10654 9.66498626816481e-10 1.0084410200556869e-8 6.123397456890912e-9 51053/8454/28227/898/1017/6119/6118/4173/5518/9134/1019/10197/8318/6117/990/5934/1874/7316/891/993/7027/7465/890/8900/983/207/5933/5111/208/4609/6233/55388 32 Human_herpesvirus_6A R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 14/786 27/10654 1.0253831252443057e-9 1.0500682745557426e-8 6.376164073156599e-9 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 14 Human_herpesvirus_6A R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 14/786 27/10654 1.0253831252443057e-9 1.0500682745557426e-8 6.376164073156599e-9 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 14 Human_herpesvirus_6A R-HSA-167169 HIV Transcription Elongation 18/786 46/10654 1.3595944041360507e-9 1.3546949648418667e-8 8.22590070970887e-9 2962/1025/2963/5437/6917/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 18 Human_herpesvirus_6A R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 18/786 46/10654 1.3595944041360507e-9 1.3546949648418667e-8 8.22590070970887e-9 2962/1025/2963/5437/6917/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 18 Human_herpesvirus_6A R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 18/786 46/10654 1.3595944041360507e-9 1.3546949648418667e-8 8.22590070970887e-9 2962/1025/2963/5437/6917/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 18 Human_herpesvirus_6A R-HSA-69618 Mitotic Spindle Checkpoint 29/786 112/10654 1.379931371222095e-9 1.3626822290818187e-8 8.274400515410681e-9 701/7514/348995/81565/79023/1062/5518/699/57122/64105/5903/5347/11065/54908/332/8881/55143/5501/1058/8655/991/4085/55746/140735/9212/11004/1063/23279/79902 29 Human_herpesvirus_6A R-HSA-5663220 RHO GTPases Activate Formins 33/786 140/10654 1.4209461913684774e-9 1.3907668032332177e-8 8.444934048375302e-9 701/7514/23380/388/348995/81565/79023/1062/5518/699/57122/64105/5903/5347/387/54908/332/71/55143/5501/1058/8655/991/4085/55746/140735/9212/389/11004/1063/23279/5879/79902 33 Human_herpesvirus_6A R-HSA-2500257 Resolution of Sister Chromatid Cohesion 31/786 126/10654 1.4645727861135308e-9 1.42089254512418e-8 8.627861842478602e-9 701/7514/348995/81565/79023/9133/1062/5518/699/57122/64105/5903/5347/113130/54908/332/55143/891/5501/1058/8655/991/4085/55746/983/140735/9212/11004/1063/23279/79902 31 Human_herpesvirus_6A R-HSA-73894 DNA Repair 57/786 334/10654 1.4983756017299175e-9 1.441046448272425e-8 8.750239211933065e-9 10450/672/51750/1017/6119/7014/6118/22976/11200/545/25913/56949/5437/6917/472/5441/5434/5440/55247/7706/4436/221120/151987/5438/3981/580/9716/6117/5431/11073/8450/5435/9156/7316/84126/5433/322/328/27339/2547/890/5439/1111/10987/5430/7157/8900/5432/91603/5436/641/5111/8924/6233/51138/7415/7517 57 Human_herpesvirus_6A R-HSA-109606 Intrinsic Pathway for Apoptosis 19/786 53/10654 2.7017364049717483e-9 2.575965917154098e-8 1.564163181825749e-8 7533/2810/598/7534/708/7531/7027/8655/6774/7157/7532/90427/207/10971/140735/7529/5594/208/5595 19 Human_herpesvirus_6A R-HSA-69473 G2/M DNA damage checkpoint 26/786 95/10654 2.7315616977647877e-9 2.5821429382289363e-8 1.567913956971601e-8 672/7533/2810/6119/6118/11200/545/472/7534/580/6117/11073/995/9156/84126/891/7531/7465/1111/7157/983/7532/10971/641/8924/7529 26 Human_herpesvirus_6A R-HSA-5655253 Signaling by FGFR2 in disease 17/786 43/10654 3.249460118835009e-9 3.04568041646739e-8 1.849380513663457e-8 2962/2963/5437/5441/5434/5440/5438/5431/3845/5435/4686/5433/5439/5430/5432/22916/5436 17 Human_herpesvirus_6A R-HSA-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase 10/786 14/10654 3.446424194669022e-9 3.203147192692385e-8 1.9449965822192268e-8 5576/5573/808/5575/801/5567/5577/5568/805/5566 10 Human_herpesvirus_6A R-HSA-913531 Interferon Signaling 40/786 199/10654 4.0218690294861714e-9 3.7068226221764215e-8 2.2508354743966467e-8 23165/9883/9972/348995/2209/815/79023/6059/57122/23636/5903/23225/7706/5300/8021/9775/10762/55706/7175/129401/9470/23511/9631/7316/10612/53371/816/55746/2316/817/8086/4734/8480/9830/23279/4927/9688/6233/5595/79902 40 Human_herpesvirus_6A R-HSA-114452 Activation of BH3-only proteins 14/786 30/10654 6.028401587277859e-9 5.51025797977629e-8 3.3459071010728786e-008 7533/2810/7534/7531/7027/8655/7157/7532/90427/207/10971/140735/7529/208 14 Human_herpesvirus_6A R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 11/786 18/10654 6.4825002594020735e-9 5.8767584318841744e-8 3.568451393872755e-8 2810/5934/995/1874/891/7027/7157/983/6790/5933/5111 11 Human_herpesvirus_6A R-HSA-180024 DARPP-32 events 13/786 26/10654 7.348069543895597e-9 6.607288549226448e-8 4.012039682503544e-8 5518/5576/5573/808/5575/801/1020/5567/5499/5577/5568/805/5566 13 Human_herpesvirus_6A R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 70/786 473/10654 1.0869757773118234e-8 9.695122658926426e-8 5.887016518887465e-8 2962/5898/1003/3178/5170/1432/51741/2963/5437/5518/5441/5434/5440/4670/387/8065/6464/1956/8851/4914/160/5438/9146/3320/808/5431/71/3845/5435/4686/7316/1499/2065/5433/6300/801/5439/1111/1020/3630/5567/3185/6774/5430/2066/5432/22916/207/4734/5436/5725/11140/10768/9550/10413/2099/7529/5594/208/51382/30011/5879/6233/5568/5595/805/3187/79109/7074/5566 70 Human_herpesvirus_6A R-HSA-1226099 Signaling by FGFR in disease 20/786 63/10654 1.1629783330300264e-8 1.0290032290649674e-7 6.248254117668688e-8 2962/399687/2963/5437/8805/5441/5434/5440/5438/5431/3845/5435/4686/5433/5439/6774/5430/5432/22916/5436 20 Human_herpesvirus_6A R-HSA-6804757 Regulation of TP53 Degradation 15/786 36/10654 1.1748513319091512e-8 1.0312583913424773e-7 6.261947784110598e-8 1017/5170/11200/5518/472/7316/890/7157/8900/983/207/208/6233/4193/79109 15 Human_herpesvirus_6A R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 24/786 88/10654 1.2031685817895502e-8 1.047798780676569e-7 6.362383383188836e-8 8454/22995/9133/5518/5347/23291/3320/7316/891/7531/10142/4659/11190/4218/8655/10733/983/7532/6790/4751/5500/5577/6233/5566 24 Human_herpesvirus_6A R-HSA-264876 Insulin processing 13/786 27/10654 1.321913550407175e-8 1.1422159271486996e-7 6.935697739800802e-8 4644/55763/25924/54536/60412/5873/10640/3630/11336/149371/55770/23265/6844 13 Human_herpesvirus_6A R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 17/786 47/10654 1.5958909983812656e-8 1.3371632153103635e-7 8.119445430360825e-8 409/8826/815/4140/808/71/3845/408/801/816/8844/817/5245/7529/5594/5595/805 17 Human_herpesvirus_6A R-HSA-6802949 Signaling by RAS mutants 17/786 47/10654 1.5958909983812656e-8 1.3371632153103635e-7 8.119445430360825e-8 409/8826/815/4140/808/71/3845/408/801/816/8844/817/5245/7529/5594/5595/805 17 Human_herpesvirus_6A R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 17/786 47/10654 1.5958909983812656e-8 1.3371632153103635e-7 8.119445430360825e-8 409/8826/815/4140/808/71/3845/408/801/816/8844/817/5245/7529/5594/5595/805 17 Human_herpesvirus_6A R-HSA-9649948 Signaling downstream of RAS mutants 17/786 47/10654 1.5958909983812656e-8 1.3371632153103635e-7 8.119445430360825e-8 409/8826/815/4140/808/71/3845/408/801/816/8844/817/5245/7529/5594/5595/805 17 Human_herpesvirus_6A R-HSA-6806003 Regulation of TP53 Expression and Degradation 15/786 37/10654 1.8422711799019976e-8 1.5319939285500823e-7 9.302485261396711e-8 1017/5170/11200/5518/472/7316/890/7157/8900/983/207/208/6233/4193/79109 15 Human_herpesvirus_6A R-HSA-6802957 Oncogenic MAPK signaling 21/786 71/10654 2.060864563331713e-8 1.7009822440633392e-7 1.0328606373964123e-7 409/8826/815/8805/4140/808/71/3845/408/10142/801/4763/816/8844/817/5245/7529/5594/57670/5595/805 21 Human_herpesvirus_6A R-HSA-5696398 Nucleotide Excision Repair 27/786 111/10654 2.185658597265276e-8 1.7906210433891818e-7 1.0872905926356694e-7 10450/6119/6118/56949/5437/6917/5441/5434/5440/5438/9716/6117/5431/8450/5435/7316/5433/27339/5439/10987/5430/5432/91603/5436/5111/6233/51138 27 Human_herpesvirus_6A R-HSA-203927 MicroRNA (miRNA) biogenesis 12/786 24/10654 2.8284407871312857e-8 2.3001878754170604e-7 1.3967068283202479e-7 5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 12 Human_herpesvirus_6A R-HSA-5619102 SLC transporter disorders 25/786 99/10654 3.258948429523023e-8 2.630946688359462e-7 1.5975482889248468e-7 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/116085/53371/55746/8086/8480/23279/4927/9688/79902 25 Human_herpesvirus_6A R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 17/786 49/10654 3.287165835398069e-8 2.6344966767755537e-7 1.5997038924362836e-7 898/1017/2810/9134/5934/995/1874/891/7027/890/7157/8900/983/6790/5933/5111/1263 17 Human_herpesvirus_6A R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 23/786 86/10654 3.626042392198251e-8 2.8851819322095437e-7 1.7519235488242972e-7 10097/10092/4644/4650/2209/917/3320/71/10095/2214/2212/10093/10109/4627/10552/10768/4620/10094/4641/5594/5879/5595/10096 23 Human_herpesvirus_6A R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 13/786 29/10654 3.891948446179478e-8 3.074639272481788e-7 1.8669647433552684e-7 5437/5441/5434/5440/5438/3320/5431/5435/5433/5439/5430/5432/5436 13 Human_herpesvirus_6A R-HSA-6807505 RNA polymerase II transcribes snRNA genes 21/786 74/10654 4.611414401767649e-8 3.6171803747198726e-7 2.1964034254033295e-7 2962/1025/2963/5437/8812/5441/5434/5440/51593/84524/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436/51585 21 Human_herpesvirus_6A R-HSA-68882 Mitotic Anaphase 38/786 201/10654 5.575471720205617e-8 4.342585720103811e-7 2.6368798795338646e-7 701/7514/348995/81565/79023/1062/5518/699/57122/64105/5903/5347/113130/10197/11065/54908/332/7443/8881/55143/7316/5501/1058/8655/991/5520/4085/55746/7112/140735/9212/11004/9232/1063/23279/6233/9700/79902 38 Human_herpesvirus_6A R-HSA-2555396 Mitotic Metaphase and Anaphase 38/786 202/10654 6.394156251275583e-8 4.945410359378178e-7 3.002923583595011e-7 701/7514/348995/81565/79023/1062/5518/699/57122/64105/5903/5347/113130/10197/11065/54908/332/7443/8881/55143/7316/5501/1058/8655/991/5520/4085/55746/7112/140735/9212/11004/9232/1063/23279/6233/9700/79902 38 Human_herpesvirus_6A R-HSA-674695 RNA Polymerase II Pre-transcription Events 22/786 84/10654 1.0791904211740886e-7 8.288781984850985e-7 5.033066437931787e-7 2962/1025/2963/5437/8812/6917/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436/80349/8148/123169 22 Human_herpesvirus_6A R-HSA-167172 Transcription of the HIV genome 20/786 73/10654 1.8274766405287533e-7 1.3939235616722766e-6 8.464102335080541e-7 2962/1025/2963/5437/8812/6917/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436/8148 20 Human_herpesvirus_6A R-HSA-6802952 Signaling by BRAF and RAF fusions 19/786 67/10654 2.0399561851383492e-7 1.5453366717554892e-6 9.38350429789666e-7 409/8826/815/8805/4140/808/71/3845/408/10142/801/816/8844/817/7529/5594/57670/5595/805 19 Human_herpesvirus_6A R-HSA-111447 Activation of BAD and translocation to mitochondria 9/786 15/10654 2.0669336064616286e-7 1.5551214753377968e-6 9.442919018421188e-7 7533/2810/7534/7531/7532/207/10971/7529/208 9 Human_herpesvirus_6A R-HSA-163615 PKA activation 10/786 19/10654 2.2598317148053387e-7 1.6887661328207463e-6 1.0254428407153671e-6 5576/5573/808/5575/801/5567/5577/5568/805/5566 10 Human_herpesvirus_6A R-HSA-111996 Ca-dependent events 14/786 38/10654 2.2942871274568225e-7 1.7030077603807017e-6 1.0340905597438734e-6 815/5576/5573/808/5575/801/816/5567/817/5594/5577/5568/805/5566 14 Human_herpesvirus_6A R-HSA-438064 Post NMDA receptor activation events 21/786 81/10654 2.530064448620804e-7 1.8655008534497395e-6 1.1327586794526827e-6 5170/815/5576/5573/808/3845/2890/5575/801/2891/816/5567/2066/817/5594/5577/5879/5568/5595/805/5566 21 Human_herpesvirus_6A R-HSA-2467813 Separation of Sister Chromatids 35/786 190/10654 3.5989982160926463e-7 2.636087435098322e-6 1.600669823539288e-6 701/7514/348995/81565/79023/1062/5518/699/57122/64105/5903/5347/113130/10197/11065/54908/332/8881/55143/7316/5501/1058/8655/991/4085/55746/140735/9212/11004/9232/1063/23279/6233/9700/79902 35 Human_herpesvirus_6A R-HSA-5625900 RHO GTPases activate CIT 10/786 20/10654 4.221543943808988e-7 3.0717286854294346e-6 1.8651973934557718e-6 9055/388/9928/387/4659/4627/4629/5500/389/5879 10 Human_herpesvirus_6A R-HSA-156711 Polo-like kinase mediated events 9/786 16/10654 4.415260242590532e-7 3.191684855101391e-6 1.9380364876317572e-6 9088/9133/5347/2305/995/891/993/7465/1063 9 Human_herpesvirus_6A R-HSA-167161 HIV Transcription Initiation 15/786 47/10654 7.34931678221479e-7 5.094174020217227e-6 3.0932549965723714e-6 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/8148 15 Human_herpesvirus_6A R-HSA-167162 RNA Polymerase II HIV Promoter Escape 15/786 47/10654 7.34931678221479e-7 5.094174020217227e-6 3.0932549965723714e-6 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/8148 15 Human_herpesvirus_6A R-HSA-73776 RNA Polymerase II Promoter Escape 15/786 47/10654 7.34931678221479e-7 5.094174020217227e-6 3.0932549965723714e-6 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/8148 15 Human_herpesvirus_6A R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 15/786 47/10654 7.34931678221479e-7 5.094174020217227e-6 3.0932549965723714e-6 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/8148 15 Human_herpesvirus_6A R-HSA-75953 RNA Polymerase II Transcription Initiation 15/786 47/10654 7.34931678221479e-7 5.094174020217227e-6 3.0932549965723714e-6 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/8148 15 Human_herpesvirus_6A R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 15/786 47/10654 7.34931678221479e-7 5.094174020217227e-6 3.0932549965723714e-6 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/8148 15 Human_herpesvirus_6A R-HSA-442755 Activation of NMDA receptors and postsynaptic events 22/786 93/10654 7.36951033666145e-7 5.094174020217227e-6 3.0932549965723714e-6 5170/815/8573/5576/5573/808/3845/2890/5575/801/2891/816/5567/2066/817/5594/5577/5879/5568/5595/805/5566 22 Human_herpesvirus_6A R-HSA-111931 PKA-mediated phosphorylation of CREB 10/786 21/10654 7.528015322665534e-7 5.139496880782766e-6 3.1207756828204094e-6 5576/5573/808/5575/801/5567/5577/5568/805/5566 10 Human_herpesvirus_6A R-HSA-5620916 VxPx cargo-targeting to cilium 10/786 21/10654 7.528015322665534e-7 5.139496880782766e-6 3.1207756828204094e-6 55763/54536/8766/60412/10640/4218/11336/149371/55770/23265 10 Human_herpesvirus_6A R-HSA-111933 Calmodulin induced events 13/786 36/10654 8.152579684007974e-7 5.498020201532207e-6 3.3384761478800307e-6 815/5576/5573/808/5575/801/816/5567/817/5577/5568/805/5566 13 Human_herpesvirus_6A R-HSA-111997 CaM pathway 13/786 36/10654 8.152579684007974e-7 5.498020201532207e-6 3.3384761478800307e-6 815/5576/5573/808/5575/801/816/5567/817/5577/5568/805/5566 13 Human_herpesvirus_6A R-HSA-1489509 DAG and IP3 signaling 14/786 42/10654 9.493684603708794e-7 6.363645558607228e-6 3.864096189579719e-6 815/5576/5573/808/5575/801/816/5567/817/10768/5577/5568/805/5566 14 Human_herpesvirus_6A R-HSA-9006925 Intracellular signaling by second messengers 47/786 305/10654 9.62020588629805e-7 6.409607054364846e-6 3.892004664209356e-6 10014/5170/815/5518/1956/10197/5576/5573/4343/8726/808/23512/2100/7316/2065/5575/1459/801/6615/816/3630/5567/2146/5978/7157/1107/2066/1457/23028/817/207/4734/6045/10768/2099/5594/208/1108/5577/5879/6233/5568/5595/4193/805/79109/5566 47 Human_herpesvirus_6A R-HSA-111367 SLBP independent Processing of Histone Pre-mRNAs 7/786 10/10654 1.1419838667760342e-6 7.56307878236104e-6 4.592409120725559e-6 6637/6635/6634/4686/22916/6628/6636 7 Human_herpesvirus_6A R-HSA-176187 Activation of ATR in response to replication stress 13/786 37/10654 1.1727037578537052e-6 7.72029973920356e-6 4.68787592425228e-6 1017/6119/6118/4173/545/8318/6117/990/995/84126/993/1111/55388 13 Human_herpesvirus_6A R-HSA-5673000 RAF activation 12/786 32/10654 1.3589878408902648e-6 8.893731077068833e-6 5.400400140068446e-6 815/5518/4140/808/3845/801/816/8844/817/5245/7529/805 12 Human_herpesvirus_6A R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 9/786 19/10654 2.911029446313747e-6 1.890498250434492e-5 1.1479374548179364e-5 7153/990/5934/1874/993/7027/5933/5111/4609 9 Human_herpesvirus_6A R-HSA-77588 SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs 7/786 11/10654 2.9400153623393547e-6 1.890498250434492e-5 1.1479374548179364e-5 6637/6635/6634/4686/22916/6628/6636 7 Human_herpesvirus_6A R-HSA-9614399 Regulation of localization of FOXO transcription factors 7/786 11/10654 2.9400153623393547e-6 1.890498250434492e-5 1.1479374548179364e-5 2810/7534/7532/207/10971/7529/208 7 Human_herpesvirus_6A R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 20/786 86/10654 3.107967157429197e-6 1.9642352434952525e-5 1.1927116068810993e-5 701/8454/1017/5347/10197/11065/8881/7316/891/890/991/4085/8900/983/8556/6790/4751/9212/9232/6233 20 Human_herpesvirus_6A R-HSA-453276 Regulation of mitotic cell cycle 20/786 86/10654 3.107967157429197e-6 1.9642352434952525e-5 1.1927116068810993e-5 701/8454/1017/5347/10197/11065/8881/7316/891/890/991/4085/8900/983/8556/6790/4751/9212/9232/6233 20 Human_herpesvirus_6A R-HSA-5628897 TP53 Regulates Metabolic Genes 20/786 86/10654 3.107967157429197e-6 1.9642352434952525e-5 1.1927116068810993e-5 9377/7533/2810/7534/1329/4343/1340/1327/4697/10128/7531/84987/7157/7532/207/10971/1345/9997/7529/208 20 Human_herpesvirus_6A R-HSA-5218920 VEGFR2 mediated vascular permeability 11/786 29/10654 3.3100131162727952e-6 2.0800423332941544e-5 1.2630313206830401e-5 1003/5170/3320/808/1499/801/207/208/5879/805/79109 11 Human_herpesvirus_6A R-HSA-5627123 RHO GTPases activate PAKs 10/786 24/10654 3.412270981337032e-6 2.13218740415749e-5 1.2946945501593971e-5 2017/808/801/4659/4627/2316/4629/5500/5879/805 10 Human_herpesvirus_6A R-HSA-5625740 RHO GTPases activate PKNs 21/786 95/10654 4.21767186161401e-6 2.620643302778143e-5 1.5912919264989582e-5 388/7533/2810/5170/29941/387/7534/995/7531/4659/5586/5585/4627/7532/23028/10971/4629/5500/389/7529/5879 21 Human_herpesvirus_6A R-HSA-5619115 Disorders of transmembrane transporters 31/786 176/10654 4.444692415757588e-6 2.746273637892677e-5 1.6675764547211648e-5 1080/23165/9883/9972/348995/79023/57122/23636/5903/23225/10197/8021/10762/55706/7175/129401/23511/9631/7316/116085/53371/10956/55746/8086/8480/23279/4927/9688/6233/7415/79902 31 Human_herpesvirus_6A R-HSA-5685942 HDR through Homologous Recombination (HRR) 17/786 67/10654 4.819493159598884e-6 2.9613107969535367e-5 1.7981500794292912e-5 672/51750/6119/6118/545/472/580/6117/11073/9156/7316/84126/1111/641/5111/6233/7517 17 Human_herpesvirus_6A R-HSA-112043 PLC beta mediated events 15/786 54/10654 5.193550991434533e-6 3.138834642910707e-5 1.9059450863015428e-5 815/5576/5573/808/5575/801/816/5567/817/10768/5594/5577/5568/805/5566 15 Human_herpesvirus_6A R-HSA-8848021 Signaling by PTK6 15/786 54/10654 5.193550991434533e-6 3.138834642910707e-5 1.9059450863015428e-5 898/1017/3091/1019/387/1956/6421/3845/7316/2065/6774/2066/207/5879/6233 15 Human_herpesvirus_6A R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 15/786 54/10654 5.193550991434533e-6 3.138834642910707e-5 1.9059450863015428e-5 898/1017/3091/1019/387/1956/6421/3845/7316/2065/6774/2066/207/5879/6233 15 Human_herpesvirus_6A R-HSA-69242 S Phase 29/786 161/10654 5.714496644999194e-6 3.4189288220603906e-005 2.0760222598977145e-5 8454/898/1017/6119/6118/4173/9134/1019/994/113130/10197/11065/8318/6117/8881/990/5934/1874/7316/993/7027/7465/890/8900/207/5111/208/4609/6233 29 Human_herpesvirus_6A R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 12/786 36/10654 5.718823074874975e-6 3.4189288220603906e-005 2.0760222598977145e-5 10097/10092/71/10095/10093/10109/10552/10094/5594/5879/5595/10096 12 Human_herpesvirus_6A R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 13/786 42/10654 5.942736270903399e-6 3.5336915675371825e-5 2.1457078329577638e-5 672/6119/6118/545/472/580/6117/11073/9156/84126/1111/641/7517 13 Human_herpesvirus_6A R-HSA-8939211 ESR-mediated signaling 36/786 223/10654 6.225435243173709e-6 3.6819953898129e-5 2.23576002541223e-5 2962/7514/1025/5170/2963/5437/5441/5434/5440/6464/1956/5438/4343/3320/808/5431/3845/2100/5435/5433/801/5439/1655/5430/2066/5432/861/23028/207/5436/2099/5594/208/4609/5595/805 36 Human_herpesvirus_6A R-HSA-112040 G-protein mediated events 15/786 55/10654 6.6606422381873225e-6 3.9184416571463715e-5 2.3793335654890883e-5 815/5576/5573/808/5575/801/816/5567/817/10768/5594/5577/5568/805/5566 15 Human_herpesvirus_6A R-HSA-8856828 Clathrin-mediated endocytosis 27/786 146/10654 7.19347056772419e-6 4.2095124062978596e-5 2.556075868676153e-5 10097/409/1080/10092/29978/2017/1956/160/917/9146/71/408/7316/3312/10093/10987/10109/10552/10094/4738/1212/30011/6233/1601/51138/10096/6844 27 Human_herpesvirus_6A R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 19/786 85/10654 1.011854522128483e-5 5.890058428811064e-5 3.576527341373807e-5 8454/898/1017/9134/1019/994/10197/5934/1874/7316/993/7027/7465/890/8900/207/208/4609/6233 19 Human_herpesvirus_6A R-HSA-5689896 Ovarian tumor domain proteases 12/786 38/10654 1.0779923531230634e-5 6.242196557874912e-5 3.790350627128765e-5 64127/387/7706/8517/7316/79155/8737/7157/983/2099/6233/7415 12 Human_herpesvirus_6A R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 12/786 39/10654 1.4536380294720661e-5 8.373560732271382e-5 5.0845453004560206e-5 672/6119/6118/545/472/580/6117/11073/9156/84126/1111/641 12 Human_herpesvirus_6A R-HSA-170834 Signaling by TGF-beta Receptor Complex 17/786 73/10654 1.660302334799896e-5 9.465434960250953e-5 5.747546877929102e-5 22938/7514/57154/1025/8812/387/57530/1874/7316/7027/5501/5499/4738/5933/5500/4609/6233 17 Human_herpesvirus_6A R-HSA-8854518 AURKA Activation by TPX2 17/786 73/10654 1.660302334799896e-5 9.465434960250953e-5 5.747546877929102e-5 22995/5518/5347/3320/7531/10142/11190/8655/10733/983/7532/6790/22974/4751/3161/5577/5566 17 Human_herpesvirus_6A R-HSA-69205 G1/S-Specific Transcription 10/786 28/10654 1.7396968366484382e-5 9.867203596580373e-5 5.9915065143411795e-5 898/8318/990/5934/1874/7027/8900/983/5933/5111 10 Human_herpesvirus_6A R-HSA-8863795 Downregulation of ERBB2 signaling 10/786 29/10654 2.4811155340279953e-5 1.400058051344369e-4 8.501351829805911e-5 8065/1956/3320/7316/2065/2066/207/11140/208/6233 10 Human_herpesvirus_6A R-HSA-69202 Cyclin E associated events during G1/S transition 18/786 83/10654 2.6700854074046968e-5 1.4990428733957332e-4 9.102401762886435e-5 8454/898/1017/9134/1019/10197/5934/1874/7316/993/7027/7465/890/8900/207/208/4609/6233 18 Human_herpesvirus_6A R-HSA-4420097 VEGFA-VEGFR2 Pathway 20/786 99/10654 2.917048163235122e-5 1.6251452084020375e-4 9.868113095655277e-5 1003/5170/1432/387/3320/808/71/3845/1499/6300/801/5567/207/10768/208/5879/5568/805/79109/5566 20 Human_herpesvirus_6A R-HSA-5693532 DNA Double-Strand Break Repair 28/786 166/10654 2.924085863218856e-5 1.6251452084020375e-4 9.868113095655277e-5 672/51750/1017/6119/6118/22976/11200/545/472/151987/3981/580/6117/11073/9156/7316/84126/322/2547/890/1111/7157/8900/641/5111/8924/6233/7517 28 Human_herpesvirus_6A R-HSA-3928662 EPHB-mediated forward signaling 12/786 42/10654 3.344862328820665e-5 1.849708867837828e-4 1.1231695609408338e-4 10097/10092/387/71/10095/10093/10109/10552/10094/5879/7074/10096 12 Human_herpesvirus_6A R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 10/786 30/10654 3.477655532918558e-5 1.9135756315462313e-4 1.1619503692076668e-4 5170/815/808/3845/801/816/817/5594/5595/805 10 Human_herpesvirus_6A R-HSA-9620244 Long-term potentiation 9/786 25/10654 4.2975297512406056e-5 2.3530039133030247e-4 1.4287774785260585e-4 815/808/2890/801/2891/816/2066/817/805 9 Human_herpesvirus_6A R-HSA-430039 mRNA decay by 5' to 3' exoribonuclease 7/786 15/10654 4.406823441586633e-5 2.4009589785196136e-4 1.4578964769158785e-4 51690/23658/54464/11157/57819/27258/25804 7 Human_herpesvirus_6A R-HSA-5685938 HDR through Single Strand Annealing (SSA) 11/786 37/10654 4.73408985747843e-5 2.566454388823646e-4 1.55838764639715e-4 672/6119/6118/545/472/580/6117/11073/9156/84126/641 11 Human_herpesvirus_6A R-HSA-1227986 Signaling by ERBB2 13/786 50/10654 4.756990503696631e-5 2.566454388823646e-4 1.55838764639715e-4 387/8065/6464/1956/3320/3845/7316/2065/2066/207/11140/208/6233 13 Human_herpesvirus_6A R-HSA-2514853 Condensation of Prometaphase Chromosomes 6/786 11/10654 5.2964017771211704e-5 2.843602119172822e-4 1.726675694329743e-4 9133/64151/891/1459/1457/983 6 Human_herpesvirus_6A R-HSA-69231 Cyclin D associated events in G1 12/786 44/10654 5.56159248653643e-5 2.957269851014083e-4 1.7956963595193535e-4 8454/28227/5518/1019/5934/1021/1874/7316/7027/5520/5933/6233 12 Human_herpesvirus_6A R-HSA-69236 G1 Phase 12/786 44/10654 5.56159248653643e-5 2.957269851014083e-4 1.7956963595193535e-4 8454/28227/5518/1019/5934/1021/1874/7316/7027/5520/5933/6233 12 Human_herpesvirus_6A R-HSA-5693607 Processing of DNA double-strand break ends 19/786 98/10654 8.273946340610838e-5 4.378461556323247e-4 2.658664198091017e-4 672/1017/6119/6118/545/472/151987/580/6117/11073/9156/7316/84126/890/1111/8900/641/8924/6233 19 Human_herpesvirus_6A R-HSA-2559585 Oncogene Induced Senescence 10/786 33/10654 8.743904450923538e-5 4.60512301081973e-4 2.7962962604958483e-4 1019/4343/1021/7316/7027/7157/5594/6233/5595/4193 10 Human_herpesvirus_6A R-HSA-194138 Signaling by VEGF 20/786 107/10654 9.276009594774794e-5 4.8622116643701056e-4 2.9524041513925256e-4 1003/5170/1432/387/3320/808/71/3845/1499/6300/801/5567/207/10768/208/5879/5568/805/79109/5566 20 Human_herpesvirus_6A R-HSA-111885 Opioid Signalling 18/786 91/10654 9.644516427756913e-5 5.031526023159975e-4 3.0552142407690717e-4 815/5518/5576/5573/808/5575/801/1020/816/5567/817/10768/5499/5594/5577/5568/805/5566 18 Human_herpesvirus_6A R-HSA-111932 CaMK IV-mediated phosphorylation of CREB 6/786 12/10654 9.93218807570903e-5 5.133177575576723e-4 3.116938510724231e-4 815/808/801/816/817/805 6 Human_herpesvirus_6A R-HSA-3371511 HSF1 activation 6/786 12/10654 9.93218807570903e-5 5.133177575576723e-4 3.116938510724231e-4 6119/6118/3320/6117/7531/7415 6 Human_herpesvirus_6A R-HSA-2682334 EPH-Ephrin signaling 18/786 92/10654 1.1181037141403291e-4 5.751733524833507e-4 3.492534490191089e-4 10097/10092/387/160/71/10095/10093/10109/6386/4627/10552/4629/10094/1969/1212/5879/7074/10096 18 Human_herpesvirus_6A R-HSA-5683057 MAPK family signaling cascades 40/786 294/10654 1.1467004973198377e-4 5.871531250165466e-4 3.5652773747078776e-4 409/7514/8826/815/9462/5518/6464/1956/10197/6711/4140/1843/4343/808/8452/71/3845/408/7316/2065/801/4763/816/5567/8844/2066/983/817/8556/5245/7529/5594/4609/5879/6233/5568/5595/805/6709/5566 40 Human_herpesvirus_6A R-HSA-164378 PKA activation in glucagon signalling 7/786 17/10654 1.1681986533372982e-4 5.95404474926752e-4 3.6153807462003217e-4 5576/5573/5575/5567/5577/5568/5566 7 Human_herpesvirus_6A R-HSA-438066 Unblocking of NMDA receptors, glutamate binding and activation 8/786 23/10654 1.5291799192965566e-4 7.758132985055007e-4 4.710848809807837e-4 815/808/2890/801/2891/816/817/805 8 Human_herpesvirus_6A R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 14/786 63/10654 1.5665729913842658e-4 7.911551271557068e-4 4.8040065777609306e-4 5437/5441/5434/5440/8517/5435/7316/1499/2547/1660/8737/5970/9533/6233 14 Human_herpesvirus_6A R-HSA-390522 Striated Muscle Contraction 10/786 36/10654 1.9605386153144033e-4 9.811564292025927e-4 5.957721536416238e-4 7168/7169/7171/4633/7111/29766/70/29767/29765/7170 10 Human_herpesvirus_6A R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 10/786 36/10654 1.9605386153144033e-4 9.811564292025927e-4 5.957721536416238e-4 409/8826/4140/71/3845/408/8844/7529/5594/5595 10 Human_herpesvirus_6A R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 11/786 43/10654 2.1167766156473714e-4 0.0010545742959036004 6.403525276353832e-4 359/4645/5576/22841/5573/8766/5575/5567/5577/5568/5566 11 Human_herpesvirus_6A R-HSA-983231 Factors involved in megakaryocyte development and platelet production 26/786 168/10654 2.3874162760893964e-4 0.0011840728257196736 7.189858787562118e-4 1017/830/3832/10112/10749/1062/24137/5576/56992/5573/9493/5575/7465/1020/5567/7157/23303/23028/832/11004/829/5577/5879/5568/3835/5566 26 Human_herpesvirus_6A R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 22/786 132/10654 2.43553257890247e-4 0.0012025442108330945 7.302019667950074e-4 672/51750/1017/6119/6118/545/472/151987/580/6117/11073/9156/7316/84126/890/1111/8900/641/5111/8924/6233/7517 22 Human_herpesvirus_6A R-HSA-109581 Apoptosis 27/786 178/10654 2.5548400239062925e-4 0.0012558458073068264 7.625674550887553e-4 1613/7533/2810/1829/10197/598/7534/708/7316/1499/7531/7027/8655/8737/6774/7157/7532/90427/207/10971/140735/7529/5594/208/6233/5595/6709 27 Human_herpesvirus_6A R-HSA-5620912 Anchoring of the basal body to the plasma membrane 18/786 98/10654 2.5760940579659945e-4 0.0012606902779249514 7.655090866242686e-4 132320/22995/5518/5347/3320/8766/7531/10142/22832/11190/4218/8655/10733/983/7532/4751/5577/5566 18 Human_herpesvirus_6A R-HSA-110320 Translesion Synthesis by POLH 7/786 19/10654 2.6556283632525287e-4 0.001282587323038121 7.788052841898934e-4 6119/6118/6117/7316/5111/6233/7415 7 Human_herpesvirus_6A R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 7/786 19/10654 2.6556283632525287e-4 0.001282587323038121 7.788052841898934e-4 6464/1956/3320/3845/7316/11140/6233 7 Human_herpesvirus_6A R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 7/786 19/10654 2.6556283632525287e-4 0.001282587323038121 7.788052841898934e-4 6464/1956/3320/3845/7316/11140/6233 7 Human_herpesvirus_6A R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 6/786 14/10654 2.8386996358629335e-4 0.001347468582516912 8.182021087330252e-4 9133/5347/891/983/5594/5595 6 Human_herpesvirus_6A R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 6/786 14/10654 2.8386996358629335e-4 0.001347468582516912 8.182021087330252e-4 6119/6118/4436/6117/9156/5111 6 Human_herpesvirus_6A R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 6/786 14/10654 2.8386996358629335e-4 0.001347468582516912 8.182021087330252e-4 6119/6118/4436/6117/9156/5111 6 Human_herpesvirus_6A R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 6/786 14/10654 2.8386996358629335e-4 0.001347468582516912 8.182021087330252e-4 898/1017/9134/890/7157/8900 6 Human_herpesvirus_6A R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 8/786 25/10654 2.954653575757662e-4 0.0013965157499093907 8.47984247113535e-4 701/11065/8881/7316/991/4085/4751/6233 8 Human_herpesvirus_6A R-HSA-5357801 Programmed Cell Death 27/786 181/10654 3.365144545178293e-4 0.001583765900837103 9.616852048482645e-4 1613/7533/2810/1829/10197/598/7534/708/7316/1499/7531/7027/8655/8737/6774/7157/7532/90427/207/10971/140735/7529/5594/208/6233/5595/6709 27 Human_herpesvirus_6A R-HSA-69615 G1/S DNA Damage Checkpoints 14/786 68/10654 3.65802924992291e-4 0.0017075444571280792 0.001036845306602945 898/1017/11200/472/9134/10197/7316/993/890/1111/7157/8900/6233/4193 14 Human_herpesvirus_6A R-HSA-5617833 Cilium Assembly 29/786 201/10654 3.6590238367030265e-4 0.0017075444571280792 0.001036845306602945 132320/55763/22995/55112/5518/5347/3320/56623/54536/8766/7531/10142/22832/60412/10640/11190/4218/8655/10733/11336/983/7532/140735/4751/149371/5577/55770/23265/5566 29 Human_herpesvirus_6A R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 9/786 32/10654 3.690975176517149e-4 0.0017135697667797149 0.0010405039604125422 22938/1025/8812/1874/7316/7027/5933/4609/6233 9 Human_herpesvirus_6A R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 15/786 76/10654 3.702922009587268e-4 0.0017135697667797149 0.0010405039604125422 701/5347/10197/11065/8881/7316/891/890/991/4085/8900/983/4751/9232/6233 15 Human_herpesvirus_6A R-HSA-5627117 RHO GTPases Activate ROCKs 7/786 20/10654 3.827404755604229e-4 0.001763795691540949 0.001071001857050657 388/387/4659/4627/4629/5500/389 7 Human_herpesvirus_6A R-HSA-2465910 MASTL Facilitates Mitotic Progression 5/786 10/10654 0.00039754793286284783 0.001824431592308339 0.0011078208393382701 5518/55844/84930/891/983 5 Human_herpesvirus_6A R-HSA-8943724 Regulation of PTEN gene transcription 13/786 61/10654 4.132446389578531e-4 0.0018886304573858905 0.001146803304284951 10014/8726/23512/6615/2146/5978/7157/1107/23028/6045/5594/1108/5595 13 Human_herpesvirus_6A R-HSA-9009391 Extra-nuclear estrogen signaling 15/786 77/10654 4.2917319764653014e-4 0.001953356199987911 0.0011861056967662387 7514/5170/6464/1956/3320/808/3845/2100/801/207/2099/5594/208/5595/805 15 Human_herpesvirus_6A R-HSA-5358508 Mismatch Repair 6/786 15/10654 4.4373778303324494e-4 0.0020113688034211837 0.0012213317755617355 6119/6118/4436/6117/9156/5111 6 Human_herpesvirus_6A R-HSA-5693538 Homology Directed Repair 22/786 138/10654 4.626889225754697e-4 0.0020887099933406916 0.0012682944472745422 672/51750/1017/6119/6118/545/472/151987/580/6117/11073/9156/7316/84126/890/1111/8900/641/5111/8924/6233/7517 22 Human_herpesvirus_6A R-HSA-68962 Activation of the pre-replicative complex 9/786 33/10654 4.7471944508014507e-4 0.0021256668269580585 0.0012907351628430963 51053/1017/6119/6118/4173/8318/6117/990/55388 9 Human_herpesvirus_6A R-HSA-9022692 Regulation of MECP2 expression and activity 9/786 33/10654 4.7471944508014507e-4 0.0021256668269580585 0.0012907351628430963 815/4343/808/801/816/817/9212/805/5566 9 Human_herpesvirus_6A R-HSA-2559583 Cellular Senescence 28/786 195/10654 4.964585863538742e-4 0.002193850522710177 0.0013321372737118997 898/1017/7014/1432/25913/472/9134/1019/5601/11065/4343/8726/8881/23512/1021/7316/7027/890/2146/6774/7157/5970/8900/6045/5594/6233/5595/4193 28 Human_herpesvirus_6A R-HSA-5674135 MAP2K and MAPK activation 10/786 40/10654 4.992664614427574e-4 0.002193850522710177 0.0013321372737118997 409/8826/4140/71/3845/408/8844/7529/5594/5595 10 Human_herpesvirus_6A R-HSA-5675221 Negative regulation of MAPK pathway 10/786 40/10654 4.992664614427574e-4 0.002193850522710177 0.0013321372737118997 5518/4140/1843/3845/7316/8844/7529/5594/6233/5595 10 Human_herpesvirus_6A R-HSA-380259 Loss of Nlp from mitotic centrosomes 14/786 70/10654 4.998646760605467e-4 0.002193850522710177 0.0013321372737118997 22995/5518/5347/3320/7531/10142/11190/8655/10733/983/7532/4751/5577/5566 14 Human_herpesvirus_6A R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 14/786 70/10654 4.998646760605467e-4 0.002193850522710177 0.0013321372737118997 22995/5518/5347/3320/7531/10142/11190/8655/10733/983/7532/4751/5577/5566 14 Human_herpesvirus_6A R-HSA-71387 Metabolism of carbohydrates 38/786 295/10654 5.111192459707319e-4 0.0022343789962198796 0.0013567467398765424 23165/9883/9972/348995/79023/2023/5518/51084/57122/23636/5903/23225/8021/10762/808/55706/7175/129401/23511/9631/7316/801/53371/5230/5567/55746/8086/8480/3161/23279/4927/9688/6233/5568/805/1468/79902/5566 38 Human_herpesvirus_6A R-HSA-6807070 PTEN Regulation 22/786 140/10654 5.667614495998859e-4 0.0024678667844782436 0.0014985238493357943 10014/10197/4343/8726/23512/7316/1459/6615/2146/5978/7157/1107/1457/23028/207/4734/6045/5594/208/1108/6233/5595 22 Human_herpesvirus_6A R-HSA-187687 Signalling to ERKs 9/786 34/10654 6.039407777945062e-4 0.0026194450989832307 0.0015905643600945094 5898/1432/6464/4914/3845/6300/7529/5594/5595 9 Human_herpesvirus_6A R-HSA-9018519 Estrogen-dependent gene expression 23/786 150/10654 6.117046151580386e-4 0.0026427550951749635 0.001604718521672815 2962/1025/2963/5437/5441/5434/5440/5438/4343/3320/5431/5435/5433/5439/1655/5430/2066/5432/861/23028/5436/2099/4609 23 Human_herpesvirus_6A R-HSA-429914 Deadenylation-dependent mRNA decay 12/786 56/10654 6.483909458785103e-4 0.002790351697049153 0.0016943412798299798 51690/9924/28960/9775/23658/54464/11157/118460/57819/80349/27258/25804 12 Human_herpesvirus_6A R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 15/786 80/10654 6.562237194914786e-4 0.0028131140843316873 0.0017081629254816946 701/8454/1017/5347/10197/11065/8881/7316/891/890/991/4085/8900/983/6233 15 Human_herpesvirus_6A R-HSA-110312 Translesion synthesis by REV1 6/786 16/10654 6.65958409773659e-4 0.002822030655975735 0.0017135771947392395 6119/6118/6117/7316/5111/6233 6 Human_herpesvirus_6A R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 6/786 16/10654 6.65958409773659e-4 0.002822030655975735 0.0017135771947392395 5934/1874/7027/890/983/5933 6 Human_herpesvirus_6A R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 6/786 16/10654 6.65958409773659e-4 0.002822030655975735 0.0017135771947392395 8454/23291/8517/7316/79155/6233 6 Human_herpesvirus_6A R-HSA-442982 Ras activation upon Ca2+ influx through NMDA receptor 7/786 22/10654 7.391501147654482e-4 0.0030965910111007034 0.0018802941515963154 815/808/3845/801/816/817/805 7 Human_herpesvirus_6A R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 7/786 22/10654 7.391501147654482e-4 0.0030965910111007034 0.0018802941515963154 351/994/8851/995/7531/993/1020 7 Human_herpesvirus_6A R-HSA-8863678 Neurodegenerative Diseases 7/786 22/10654 7.391501147654482e-4 0.0030965910111007034 0.0018802941515963154 351/994/8851/995/7531/993/1020 7 Human_herpesvirus_6A R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 15/786 82/10654 8.586639673895119e-4 0.0035702343907248126 0.002167897155498649 22995/5518/5347/440145/3320/7531/10142/11190/8655/10733/983/7532/4751/5577/5566 15 Human_herpesvirus_6A R-HSA-380287 Centrosome maturation 15/786 82/10654 8.586639673895119e-4 0.0035702343907248126 0.002167897155498649 22995/5518/5347/440145/3320/7531/10142/11190/8655/10733/983/7532/4751/5577/5566 15 Human_herpesvirus_6A R-HSA-69306 DNA Replication 20/786 127/10654 9.652620653192661e-4 0.003969629399868092 0.0024104154916872967 51053/8454/898/1017/6119/6118/4173/9134/10197/11065/8318/6117/8881/990/7316/890/8900/5111/6233/55388 20 Human_herpesvirus_6A R-HSA-5655862 Translesion synthesis by POLK 6/786 17/10654 9.654885249227096e-4 0.003969629399868092 0.0024104154916872967 6119/6118/6117/7316/5111/6233 6 Human_herpesvirus_6A R-HSA-5656121 Translesion synthesis by POLI 6/786 17/10654 9.654885249227096e-4 0.003969629399868092 0.0024104154916872967 6119/6118/6117/7316/5111/6233 6 Human_herpesvirus_6A R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 7/786 23/10654 9.95626668506111e-4 0.004063332455231583 0.0024673133210600068 11065/8881/7316/891/991/983/6233 7 Human_herpesvirus_6A R-HSA-73980 RNA Polymerase III Transcription Termination 7/786 23/10654 9.95626668506111e-4 0.004063332455231583 0.0024673133210600068 4774/5437/5441/5434/5440/5435/9533 7 Human_herpesvirus_6A R-HSA-5620920 Cargo trafficking to the periciliary membrane 11/786 51/10654 0.0010190173285440566 0.004143504284447525 0.0025159947972566107 55763/56623/54536/8766/60412/10640/4218/11336/149371/55770/23265 11 Human_herpesvirus_6A R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 14/786 75/10654 0.0010284643673028455 0.004166599231637169 0.0025300183780189527 701/10197/11065/8881/7316/891/890/991/4085/8900/983/4751/9232/6233 14 Human_herpesvirus_6A R-HSA-166520 Signaling by NTRKs 17/786 101/10654 0.0010684828021665252 0.004312926931372908 0.002618870640730861 5898/1432/5518/387/6464/8851/4914/160/3845/6300/1020/6774/7529/5594/5879/5595/7074 17 Human_herpesvirus_6A R-HSA-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation 5/786 12/10654 0.0011028292773550108 0.004435378839107789 0.0026932251825932895 3320/808/801/207/805 5 Human_herpesvirus_6A R-HSA-9006936 Signaling by TGF-beta family members 17/786 102/10654 0.0011963228822073914 0.004793960535222372 0.0029109610940057803 22938/7514/57154/1025/8812/387/57530/1874/7316/7027/5501/5499/4738/5933/5500/4609/6233 17 Human_herpesvirus_6A R-HSA-445717 Aquaporin-mediated transport 11/786 52/10654 0.001207952062049515 0.004823086572659796 0.0029286468386380037 359/4645/5576/22841/5573/8766/5575/5567/5577/5568/5566 11 Human_herpesvirus_6A R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 15/786 85/10654 0.001260022502967773 0.004977088886722704 0.0030221592364415004 8454/64127/1432/51295/5518/5601/351/23291/8517/7316/79155/5970/5594/6233/5595 15 Human_herpesvirus_6A R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 15/786 85/10654 0.001260022502967773 0.004977088886722704 0.0030221592364415004 8454/64127/1432/51295/5518/5601/351/23291/8517/7316/79155/5970/5594/6233/5595 15 Human_herpesvirus_6A R-HSA-975871 MyD88 cascade initiated on plasma membrane 15/786 85/10654 0.001260022502967773 0.004977088886722704 0.0030221592364415004 8454/64127/1432/51295/5518/5601/351/23291/8517/7316/79155/5970/5594/6233/5595 15 Human_herpesvirus_6B R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 227/678 244/10654 2.056383738366639e-264 2.20238698379067e-261 1.2749579177873162e-261 10450/7536/2962/10212/10921/51690/10898/22938/29894/1993/8449/27238/1665/55749/23165/11017/51503/988/22827/3178/10286/9883/23451/53981/7919/6637/199746/9972/23450/348995/51213/10236/23524/2963/56949/79023/9984/5437/10250/6635/53938/6629/57122/5441/6634/5434/23636/5440/4670/10914/5094/23020/5903/6633/10569/220988/55599/23225/51593/6432/26097/8683/51691/6431/8021/9775/23658/3192/10189/3183/5438/85313/10084/8563/6430/79622/57187/6632/51340/9716/10762/5431/84248/6434/10283/9092/51362/6627/55706/7175/55110/54883/9295/5093/24148/22794/129401/23511/6936/154007/81608/5435/10946/8896/6427/10594/4686/9785/9631/8189/23398/83443/79228/6625/3312/10465/84844/5433/6631/10713/10482/27339/8175/51645/10949/5356/51692/84271/53371/11051/11338/55660/6426/3181/84950/5439/1655/10421/9343/55954/11193/3188/29107/80145/51729/3185/9129/1660/55696/4116/23350/5430/25949/84991/3190/10907/10291/5432/55746/1477/23283/10978/79869/85437/22916/9416/65109/8086/9939/6626/56339/11066/84321/4904/84324/11157/5436/5546/56259/2521/5725/1479/26121/9879/22826/11100/10081/51639/51585/3191/7307/10285/10523/285755/6429/1478/6428/8480/10772/9410/6638/24144/57819/57794/10992/57721/11325/55339/9128/57703/9877/23279/4927/10262/10181/6628/9688/27316/6636/27258/8233/3184/3187/1994/8106/25804/79902 227 Human_herpesvirus_6B R-HSA-72172 mRNA Splicing 185/678 191/10654 1.0052607120601582e-222 5.383171113082148e-220 3.116308207386491e-220 10450/7536/2962/10921/51690/10898/22938/29894/1993/8449/27238/1665/55749/11017/51503/988/22827/3178/10286/23451/53981/6637/199746/23450/10236/23524/2963/56949/5437/10250/6635/53938/6629/5441/6634/5434/5440/4670/10914/5094/23020/6633/10569/220988/55599/51593/6432/8683/51691/6431/9775/23658/3192/10189/3183/5438/85313/10084/6430/79622/6632/51340/9716/5431/6434/10283/9092/51362/6627/55110/54883/9295/5093/24148/22794/6936/154007/81608/5435/10946/8896/6427/10594/4686/9785/8189/23398/83443/6625/3312/10465/84844/5433/6631/10713/27339/8175/51645/10949/5356/51692/11051/11338/55660/6426/3181/84950/5439/1655/10421/9343/55954/11193/3188/51729/3185/9129/1660/55696/4116/23350/5430/25949/84991/3190/10907/10291/5432/1477/23283/10978/79869/85437/22916/9416/65109/9939/6626/11066/4904/11157/5436/5546/56259/2521/5725/1479/26121/9879/22826/11100/10081/51639/51585/3191/7307/10285/10523/285755/6429/1478/6428/10772/9410/6638/24144/57819/57794/10992/11325/55339/9128/57703/10262/10181/6628/27316/6636/27258/8233/3184/3187/1994/8106/25804 185 Human_herpesvirus_6B R-HSA-72163 mRNA Splicing - Major Pathway 177/678 183/10654 2.976753635382401e-212 1.062701047831517e-209 6.151957513123629e-210 10450/7536/2962/10921/51690/10898/22938/29894/1993/8449/27238/1665/55749/11017/51503/988/22827/3178/10286/23451/53981/6637/199746/23450/10236/23524/2963/56949/5437/10250/6635/53938/6629/5441/6634/5434/5440/4670/10914/5094/23020/6633/10569/220988/51593/6432/8683/51691/6431/9775/23658/3192/10189/3183/5438/85313/10084/6430/6632/51340/9716/5431/6434/10283/9092/51362/6627/55110/54883/9295/5093/24148/22794/6936/81608/5435/10946/8896/6427/10594/4686/9785/8189/23398/83443/6625/3312/10465/84844/5433/6631/10713/27339/8175/51645/10949/5356/51692/11051/11338/55660/6426/3181/84950/5439/1655/10421/9343/11193/3188/51729/3185/9129/1660/55696/4116/23350/5430/25949/84991/3190/10907/10291/5432/1477/23283/10978/79869/22916/9416/65109/9939/6626/4904/11157/5436/5546/56259/2521/5725/1479/26121/9879/22826/11100/51639/51585/3191/7307/10285/10523/285755/6429/1478/6428/10772/9410/6638/24144/57819/57794/10992/11325/55339/9128/57703/10262/10181/6628/27316/6636/27258/3184/3187/1994/8106/25804 177 Human_herpesvirus_6B R-HSA-72202 Transport of Mature Transcript to Cytoplasm 73/678 84/10654 1.0552143397755527e-76 2.8253363947490425e-74 1.6355822266521069e-74 10212/10921/10898/29894/23165/9883/53981/7919/199746/9972/348995/51213/79023/9984/10250/57122/23636/5903/10569/23225/6432/26097/8683/6431/8021/9775/10189/8563/6430/57187/10762/84248/51362/55706/7175/55110/9295/22794/129401/23511/81608/6427/4686/9785/9631/8189/79228/10482/51692/84271/53371/11338/6426/29107/80145/4116/55746/22916/65109/8086/9939/84321/84324/7307/6429/6428/8480/55339/9877/23279/4927/9688/79902 73 Human_herpesvirus_6B R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 66/678 75/10654 3.821190681673023e-70 8.184990440143614e-68 4.7382764452745495e-68 10212/10921/23165/9883/7919/199746/9972/348995/51213/79023/9984/10250/57122/23636/5903/10569/23225/6432/26097/8683/6431/8021/9775/10189/8563/6430/57187/10762/84248/51362/55706/7175/55110/9295/22794/129401/23511/6427/4686/9785/9631/79228/10482/84271/53371/11338/6426/29107/80145/4116/55746/22916/65109/8086/9939/84321/84324/7307/6429/6428/8480/9877/23279/4927/9688/79902 66 Human_herpesvirus_6B R-HSA-73856 RNA Polymerase II Transcription Termination 62/678 67/10654 3.272586757371379e-69 5.8415673619079116e-67 3.381672982617092e-67 10212/10921/10898/29894/53981/7919/6637/199746/51213/9984/10250/6635/6634/10914/10569/6432/26097/8683/6431/9775/10189/8563/6430/57187/84248/51362/55110/9295/22794/81608/6427/4686/9785/8189/79228/51692/84271/11051/11338/6426/80145/4116/1477/23283/10978/79869/22916/65109/9939/84321/84324/1479/51585/7307/6429/1478/6428/55339/9877/6628/6636/8106 62 Human_herpesvirus_6B R-HSA-72187 mRNA 3'-end processing 57/678 58/10654 3.6538034781099456e-68 5.590319321508217e-66 3.2362259377545244e-66 10212/10921/10898/29894/53981/7919/199746/51213/9984/10250/10914/10569/6432/26097/8683/6431/9775/10189/8563/6430/57187/84248/51362/55110/9295/22794/81608/6427/4686/9785/8189/79228/51692/84271/11051/11338/6426/80145/4116/1477/23283/10978/79869/22916/65109/9939/84321/84324/1479/51585/7307/6429/1478/6428/55339/9877/8106 57 Human_herpesvirus_6B R-HSA-72165 mRNA Splicing - Minor Pathway 51/678 52/10654 7.83261179492403e-61 1.0485909040454545e-58 6.070274141066124e-59 2962/23451/6637/23450/2963/5437/6635/5441/6634/5434/5440/23020/6633/55599/6432/6431/5438/79622/6632/5431/24148/154007/5435/6427/10594/4686/83443/5433/6426/5439/9343/55954/5430/10907/5432/85437/22916/9416/11066/4904/5436/10081/51639/9410/57819/10992/11325/10262/6628/6636/8233 51 Human_herpesvirus_6B R-HSA-168325 Viral Messenger RNA Synthesis 38/678 43/10654 9.184734064430756e-41 1.09298335366726e-38 6.327261244385632e-39 2962/23165/9883/9972/348995/2963/79023/5437/57122/5441/5434/23636/5440/5903/23225/8021/5438/10762/5431/55706/7175/129401/23511/5435/9631/5433/53371/5439/5430/5432/55746/8086/5436/8480/23279/4927/9688/79902 38 Human_herpesvirus_6B R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 35/678 41/10654 1.8253961483488895e-36 1.9549992748816607e-34 1.1317456119763116e-34 10898/29894/23165/9883/53981/9972/348995/79023/57122/23636/5903/23225/8021/10189/10762/55706/7175/129401/23511/81608/4686/9631/8189/10482/51692/53371/55746/22916/8086/8480/55339/23279/4927/9688/79902 35 Human_herpesvirus_6B R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 35/678 42/10654 1.0307446758752898e-35 1.0035704980567593e-33 5.809651809478907e-34 10898/29894/23165/9883/53981/9972/348995/79023/57122/23636/5903/23225/8021/10189/10762/55706/7175/129401/23511/81608/4686/9631/8189/10482/51692/53371/55746/22916/8086/8480/55339/23279/4927/9688/79902 35 Human_herpesvirus_6B R-HSA-159227 Transport of the SLBP independent Mature mRNA 28/678 34/10654 1.7542042472016524e-28 1.5656272906274747e-26 9.063388610541872e-27 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10189/10762/55706/7175/129401/23511/4686/9631/10482/53371/55746/22916/8086/8480/23279/4927/9688/79902 28 Human_herpesvirus_6B R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 28/678 35/10654 8.25294521280791e-28 6.799157171474824e-26 3.9360200245699256e-26 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10189/10762/55706/7175/129401/23511/4686/9631/10482/53371/55746/22916/8086/8480/23279/4927/9688/79902 28 Human_herpesvirus_6B R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 38/678 72/10654 6.527827860040758e-27 4.99378831293118e-25 2.890895195160908e-25 6517/5898/8773/79058/7533/2810/4644/55763/10890/7534/6810/808/71/54536/5872/8766/7531/60412/801/10640/9847/4218/4627/11336/7532/207/10971/51552/149371/4641/7529/208/6814/5879/805/55770/23265/6844 38 Human_herpesvirus_6B R-HSA-191859 snRNP Assembly 33/678 53/10654 9.521555196717931e-27 6.373491009803066e-25 3.689602638728199e-25 23165/9883/6637/9972/348995/79023/6635/57122/6634/23636/5903/6633/23225/8021/6632/10762/55706/7175/129401/23511/4686/9631/53371/55746/22916/8086/8480/23279/4927/6628/9688/6636/79902 33 Human_herpesvirus_6B R-HSA-194441 Metabolism of non-coding RNA 33/678 53/10654 9.521555196717931e-27 6.373491009803066e-25 3.689602638728199e-25 23165/9883/6637/9972/348995/79023/6635/57122/6634/23636/5903/6633/23225/8021/6632/10762/55706/7175/129401/23511/4686/9631/53371/55746/22916/8086/8480/23279/4927/6628/9688/6636/79902 33 Human_herpesvirus_6B R-HSA-3371453 Regulation of HSF1-mediated heat shock response 37/678 69/10654 1.452201724760179e-26 9.148870865989127e-25 5.2962651138312415e-25 23165/6119/6118/9883/9972/348995/545/79023/472/57122/23636/5903/23225/23411/8021/6117/10762/55706/7175/129401/23511/9631/3312/7531/53371/9531/55746/8086/22824/8480/5594/23279/4927/9688/3308/5595/79902 37 Human_herpesvirus_6B R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 27/678 35/10654 4.4364238530775007e-26 2.639672192581113e-24 1.5281015493933616e-24 23165/9883/9972/348995/79023/9133/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/891/53371/55746/983/8086/8480/23279/4927/9688/79902 27 Human_herpesvirus_6B R-HSA-3371556 Cellular response to heat stress 41/678 89/10654 6.149720710047456e-26 3.466500463400434e-24 2.0067509685418013e-24 23165/6119/6118/9883/9972/348995/815/545/79023/472/57122/23636/5903/23225/23411/8021/3320/6117/10762/55706/7175/129401/23511/9631/3312/7531/53371/816/9531/55746/817/8086/22824/8480/5594/23279/4927/9688/3308/5595/79902 41 Human_herpesvirus_6B R-HSA-4615885 SUMOylation of DNA replication proteins 30/678 45/10654 9.721431703176573e-26 5.2058266770510545e-24 3.013643827984738e-24 7153/23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/332/10762/55706/7175/55143/129401/23511/9631/53371/55746/8086/6790/5111/8480/9212/23279/4927/9688/79902 30 Human_herpesvirus_6B R-HSA-75067 Processing of Capped Intronless Pre-mRNA 24/678 28/10654 2.1235557608954067e-25 1.0830134380566574e-23 6.269545579786439e-24 10898/29894/53981/6637/6635/6634/10914/81608/4686/8189/51692/11051/1477/23283/10978/79869/22916/1479/51585/1478/55339/6628/6636/8106 24 Human_herpesvirus_6B R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 25/678 31/10654 4.159311569267947e-25 2.0248284957663506e-23 1.1721696240664217e-23 7514/23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 25 Human_herpesvirus_6B R-HSA-2980766 Nuclear Envelope Breakdown 31/678 52/10654 2.2922114661971807e-24 1.067373252303122e-22 6.1790048219228345e-023 23165/9883/9972/348995/79023/9133/57122/23636/5903/5347/23225/8021/7443/10762/55706/7175/129401/23511/9631/891/53371/55746/983/7112/8086/64900/8480/23279/4927/9688/79902 31 Human_herpesvirus_6B R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 25/678 33/10654 6.944016903677375e-24 3.0987675432660285e-22 1.7938710334499886e-22 7514/23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 25 Human_herpesvirus_6B R-HSA-69620 Cell Cycle Checkpoints 71/678 293/10654 1.1168297229324246e-23 4.784498533042508e-22 2.769737712872413e-22 701/672/7514/898/1017/7533/9088/2810/6119/6118/348995/81565/4173/11200/545/79023/9133/1062/5518/472/699/57122/9134/64105/5903/5347/10197/11065/7534/54908/332/8318/580/6117/8881/990/11073/55143/995/9156/84126/891/7531/51512/993/5501/7465/1058/890/1111/8655/991/7157/4085/8900/55746/983/7532/10971/140735/641/8924/9212/11004/7529/1063/23279/6233/4193/55388/79902 71 Human_herpesvirus_6B R-HSA-77595 Processing of Intronless Pre-mRNAs 19/678 19/10654 1.4691059289890298e-23 6.051586345950965e-22 3.503252599896917e-22 10898/29894/53981/10914/81608/4686/8189/51692/11051/1477/23283/10978/79869/22916/1479/51585/1478/55339/8106 19 Human_herpesvirus_6B R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 24/678 31/10654 2.2720169766597102e-23 8.390793731043274e-22 4.857415605272485e-22 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Human_herpesvirus_6B R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 24/678 31/10654 2.2720169766597102e-23 8.390793731043274e-22 4.857415605272485e-22 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Human_herpesvirus_6B R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 24/678 31/10654 2.2720169766597102e-23 8.390793731043274e-22 4.857415605272485e-22 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Human_herpesvirus_6B R-HSA-165054 Rev-mediated nuclear export of HIV RNA 25/678 34/10654 2.4683350892345508e-23 8.811956268567347e-22 5.101225851084739e-22 7514/23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 25 Human_herpesvirus_6B R-HSA-195258 RHO GTPase Effectors 74/678 327/10654 1.0404205428487604e-22 3.5944851657774914e-21 2.080841085697521e-21 701/10097/9055/7514/23380/388/1080/10092/7533/2810/5170/9928/1432/2017/8826/348995/81565/79023/1062/29941/5518/699/57122/64105/6280/5903/5347/387/5300/7534/54908/332/808/71/6242/55143/995/10095/1499/7531/5501/1058/801/4659/10093/8655/10109/991/5586/4085/5585/4627/55746/2316/7532/23028/10552/10971/140735/4629/10094/5500/9212/389/11004/7529/5594/1063/23279/5879/5595/805/10096/79902 74 Human_herpesvirus_6B R-HSA-162599 Late Phase of HIV Life Cycle 47/678 139/10654 1.515380794072967e-22 5.0717900951629615e-21 2.9360502885163738e-21 2962/7514/1025/23165/9883/9972/348995/2963/79023/5437/8812/6917/57122/5441/5434/23636/5440/5903/23225/8021/5438/10762/5431/55706/7175/129401/23511/5435/4686/9631/27183/5433/53371/5439/5430/5432/55746/22916/8086/5436/8480/23279/4927/9688/8148/6233/79902 47 Human_herpesvirus_6B R-HSA-177243 Interactions of Rev with host cellular proteins 25/678 36/10654 2.503204756043153e-22 8.124037253703687e-21 4.702990753778045e-21 7514/23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 25 Human_herpesvirus_6B R-HSA-180746 Nuclear import of Rev protein 24/678 33/10654 2.9503188585420487e-22 9.02797570713867e-21 5.226279120845915e-21 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Human_herpesvirus_6B R-HSA-180910 Vpr-mediated nuclear import of PICs 24/678 33/10654 2.9503188585420487e-22 9.02797570713867e-21 5.226279120845915e-21 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Human_herpesvirus_6B R-HSA-168276 NS1 Mediated Effects on Host Pathways 26/678 40/10654 4.948123995413453e-22 1.4720668886355025e-20 8.521769103212058e-21 10898/23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/8106/79902 26 Human_herpesvirus_6B R-HSA-4085377 SUMOylation of SUMOylation proteins 24/678 34/10654 9.4386836976266e-22 2.732116281123808e-20 1.581617268250944e-20 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Human_herpesvirus_6B R-HSA-162587 HIV Life Cycle 48/678 152/10654 1.5082569782224715e-21 4.2509032202007026e-20 2.460840332889296e-20 2962/7514/1025/23165/9883/9972/348995/2963/79023/5437/8812/6917/57122/5441/5434/23636/5440/5903/23225/8021/5438/10762/5431/55706/7175/129401/23511/5435/4686/9631/27183/5433/2547/53371/5439/5430/5432/55746/22916/8086/5436/8480/23279/4927/9688/8148/6233/79902 48 Human_herpesvirus_6B R-HSA-3232142 SUMOylation of ubiquitinylation proteins 25/678 38/10654 1.9974332269106922e-21 5.485258938516286e-20 3.1754066684221264e-20 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/4193/79902 25 Human_herpesvirus_6B R-HSA-6803529 FGFR2 alternative splicing 21/678 26/10654 2.734192360556764e-21 7.320800045390735e-20 4.237998158862984e-20 2962/3178/2963/5437/5441/5434/5440/4670/5438/5431/5435/4686/5433/5439/3185/5430/5432/22916/5436/5725/3187 21 Human_herpesvirus_6B R-HSA-168253 Host Interactions with Influenza Factors 26/678 42/10654 3.1431927051749348e-21 8.210632651810622e-20 4.7531206761181946e-20 10898/23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/8106/79902 26 Human_herpesvirus_6B R-HSA-3700989 Transcriptional Regulation by TP53 76/678 365/10654 5.796592435052874e-21 1.4781310709384829e-19 8.556874546982814e-20 672/2962/898/1025/1017/7533/2810/6119/6118/5170/1432/11200/2963/545/5437/8812/5518/6917/472/5441/9134/5434/5440/4436/8851/5300/7534/332/5438/580/4343/6117/5431/11073/5934/995/1874/5435/10128/9156/84126/5433/891/7531/7027/1459/890/5439/1111/1020/5430/7157/1107/8900/1457/5432/983/7532/207/10971/5436/6790/641/9997/5933/22974/5111/9212/7529/208/1108/8148/6233/4193/79109/1263 76 Human_herpesvirus_6B R-HSA-176033 Interactions of Vpr with host cellular proteins 24/678 36/10654 7.976941290937015e-21 1.9868149122310565e-19 1.1501636279955696e-19 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Human_herpesvirus_6B R-HSA-4570464 SUMOylation of RNA binding proteins 27/678 47/10654 8.861539154817052e-21 2.1569791897293325e-19 1.2486714263605847e-19 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/3183/10762/55706/7175/129401/23511/9631/53371/3190/55746/8086/6045/8480/23279/4927/9688/79902 27 Human_herpesvirus_6B R-HSA-168273 Influenza Viral RNA Transcription and Replication 44/678 134/10654 1.3374441108125747e-20 3.183116983733928e-19 1.842700774897325e-19 2962/23165/9883/9972/348995/2963/6202/79023/5437/57122/5441/5434/23636/5440/5903/23225/3921/8021/5438/3320/10762/5431/55706/7175/129401/23511/5435/9631/5433/53371/5439/5430/5432/55746/8086/5436/8480/6173/23279/4927/9688/11224/6233/79902 44 Human_herpesvirus_6B R-HSA-168254 Influenza Infection 47/678 155/10654 2.696478250530467e-20 6.278104796343761e-19 3.634383728975847e-19 2962/10898/7514/23165/9883/9972/348995/2963/6202/79023/5437/57122/5441/5434/23636/5440/5903/23225/3921/8021/5438/3320/10762/5431/55706/7175/129401/23511/5435/9631/5433/53371/5439/5430/5432/55746/8086/5436/8480/6173/23279/4927/9688/11224/6233/8106/79902 47 Human_herpesvirus_6B R-HSA-168255 Influenza Life Cycle 45/678 144/10654 4.592094634999815e-20 1.0464113519329365e-18 6.057656752552948e-19 2962/7514/23165/9883/9972/348995/2963/6202/79023/5437/57122/5441/5434/23636/5440/5903/23225/3921/8021/5438/3320/10762/5431/55706/7175/129401/23511/5435/9631/5433/53371/5439/5430/5432/55746/8086/5436/8480/6173/23279/4927/9688/11224/6233/79902 45 Human_herpesvirus_6B R-HSA-68886 M Phase 78/678 395/10654 5.090648228508259e-20 1.1358508859859053e-18 6.575420628489836e-19 701/7514/23165/9883/9972/348995/81565/22995/10112/79023/9133/1062/5518/699/57122/23636/64105/55844/5903/5347/113130/23225/10197/11065/8021/54908/332/7443/440145/3320/10762/8881/9493/55706/7175/55143/129401/23511/64151/9631/84930/891/7531/10142/5501/1459/1058/53371/11190/8655/991/5520/4085/10733/1457/55746/983/7112/7532/8086/140735/64900/4751/8480/9212/11004/5594/9232/1063/23279/4927/9688/5577/6233/9700/5595/79902/5566 78 Human_herpesvirus_6B R-HSA-6784531 tRNA processing in the nucleus 28/678 57/10654 4.833080938784864e-19 1.0563734051915488e-17 6.11532690213595e-18 10898/29894/23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/10978/8086/1478/8480/23279/4927/9688/79902 28 Human_herpesvirus_6B R-HSA-1169408 ISG15 antiviral mechanism 31/678 72/10654 7.867863599804669e-19 1.6852963830781605e-17 9.756150863757791e-18 23165/9883/9972/348995/79023/57122/23636/5903/23225/7706/5300/8021/9775/10762/55706/7175/129401/9470/23511/9631/53371/55746/8086/4734/8480/23279/4927/9688/6233/5595/79902 31 Human_herpesvirus_6B R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 32/678 80/10654 3.0833797253664007e-18 6.475097423269441e-17 3.748422411229742e-17 23165/9883/9972/348995/79023/57122/23636/5903/23225/7706/5300/8021/9775/10762/55706/7175/129401/9470/23511/9631/53371/55746/2316/8086/4734/8480/23279/4927/9688/6233/5595/79902 32 Human_herpesvirus_6B R-HSA-70171 Glycolysis 30/678 71/10654 5.549348897651498e-18 1.142952436420145e-16 6.616531377969094e-17 23165/9883/9972/348995/79023/2023/5518/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/5230/5567/55746/8086/8480/23279/4927/9688/5568/79902/5566 30 Human_herpesvirus_6B R-HSA-5578749 Transcriptional regulation by small RNAs 36/678 106/10654 1.2975386742486035e-17 2.62200739645331e-16 1.5178754302530834e-16 23165/9883/9972/348995/79023/5437/57122/5441/5434/23636/5440/5903/23225/8021/5438/10762/5431/55706/7175/129401/23511/5435/9631/5433/53371/5439/5430/5432/55746/8086/5436/8480/23279/4927/9688/79902 36 Human_herpesvirus_6B R-HSA-194315 Signaling by Rho GTPases 80/678 455/10654 2.4205848915922644e-17 4.800826701657991e-16 2.7791900607170444e-16 701/10097/9055/7514/23380/388/1080/10092/7533/2810/4650/5170/9928/1432/2017/8826/348995/81565/79023/1062/29941/5518/699/57122/64105/6280/5903/5347/387/5300/7534/54908/332/808/85360/71/6242/55143/995/10095/1499/57584/7531/5501/9824/1058/801/4659/10093/8655/10109/991/5586/4085/5585/4627/55746/2316/7532/23028/10552/10971/140735/4629/10094/5500/9212/389/11004/7529/5594/1063/23279/90627/5879/5595/805/7074/10096/79902 80 Human_herpesvirus_6B R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 47/678 182/10654 3.584806653443231e-17 6.980596228795819e-16 4.04105477297237e-16 672/7153/23165/9883/9972/348995/79023/57122/23636/5903/23225/8517/8021/332/3183/6117/10762/6294/55706/7175/55143/23512/129401/23511/9631/53371/1655/7157/5970/3190/1107/9759/55746/8086/6045/6790/641/5111/8480/8924/9212/2099/23279/4927/9688/4193/79902 47 Human_herpesvirus_6B R-HSA-8851708 Signaling by FGFR2 IIIa TM 16/678 19/10654 4.950016051021841e-17 9.46690569757927e-16 5.480374913631324e-16 2962/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 16 Human_herpesvirus_6B R-HSA-2990846 SUMOylation 47/678 188/10654 1.4394737834407753e-16 2.7046954773071412e-15 1.5657434135671593e-15 672/7153/23165/9883/9972/348995/79023/57122/23636/5903/23225/8517/8021/332/3183/6117/10762/6294/55706/7175/55143/23512/129401/23511/9631/53371/1655/7157/5970/3190/1107/9759/55746/8086/6045/6790/641/5111/8480/8924/9212/2099/23279/4927/9688/4193/79902 47 Human_herpesvirus_6B R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13/678 13/10654 2.5190038301356875e-16 4.6514708656471054e-15 2.692728232214011e-15 7533/2810/11200/7534/995/891/7531/7465/1111/983/7532/10971/7529 13 Human_herpesvirus_6B R-HSA-162906 HIV Infection 52/678 233/10654 5.946570913051635e-16 1.0794538047251357e-14 6.2489389255796845e-15 2962/7514/1025/23165/9883/9972/348995/2963/79023/5437/8812/6917/57122/5441/5434/23636/5440/5903/8065/23225/10197/160/8021/5438/10762/5431/55706/7175/129401/23511/5435/4686/9631/27183/5433/2547/53371/5439/5430/5432/55746/22916/8086/5436/8480/23279/4927/9688/8148/5879/6233/79902 52 Human_herpesvirus_6B R-HSA-4551638 SUMOylation of chromatin organization proteins 28/678 71/10654 6.327861038418345e-16 1.1295231953576747e-14 6.538789739698957e-15 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/23512/129401/23511/9631/53371/1107/9759/55746/8086/6045/8480/23279/4927/9688/79902 28 Human_herpesvirus_6B R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 29/678 77/10654 8.181106613726215e-16 1.4363877349673404e-14 8.31522311559058e-15 672/23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/6117/10762/55706/7175/129401/23511/9631/53371/55746/8086/6045/641/8480/8924/23279/4927/9688/79902 29 Human_herpesvirus_6B R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 17/678 25/10654 2.5404276919030443e-15 4.388383964561549e-14 2.5404276919030447e-14 28227/7514/1017/9088/9133/5518/994/5347/2305/995/891/993/7465/890/5520/8900/983 17 Human_herpesvirus_6B R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 16/678 23/10654 9.838845757848978e-15 1.6726037788343264e-13 9.682673602962487e-14 2962/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 16 Human_herpesvirus_6B R-HSA-5654738 Signaling by FGFR2 27/678 73/10654 1.3902511023445257e-14 2.3264983290796674e-13 1.3468057553962596e-13 2962/3178/2963/5437/5518/5441/5434/5440/4670/6464/5438/5431/3845/5435/4686/5433/5439/3185/5430/5432/22916/5436/5725/5594/6233/5595/3187 27 Human_herpesvirus_6B R-HSA-211000 Gene Silencing by RNA 37/678 136/10654 1.4938837715087355e-14 2.461460798901316e-13 1.424935289746794e-13 23165/9883/9972/348995/79023/5437/57122/5441/5434/23636/5440/5903/23225/8021/5438/3320/10762/5431/55706/7175/129401/23511/5435/9631/5433/53371/5439/5430/5432/55746/8086/5436/8480/23279/4927/9688/79902 37 Human_herpesvirus_6B R-HSA-70326 Glucose metabolism 30/678 91/10654 1.719967009822956e-14 2.791037375030888e-13 1.6157265849852013e-13 23165/9883/9972/348995/79023/2023/5518/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/5230/5567/55746/8086/8480/23279/4927/9688/5568/79902/5566 30 Human_herpesvirus_6B R-HSA-5663202 Diseases of signal transduction 66/678 377/10654 2.3514467948654987e-14 3.758805249702909e-13 2.1759656907710587e-13 10014/8454/2962/22938/409/399687/5170/8826/2963/815/5437/5518/8805/5441/5434/5440/6464/1956/10197/4140/5438/3320/808/5431/71/3845/79885/408/2100/5435/4686/1499/55294/2065/5433/10142/801/5439/4763/816/10956/5430/8844/2066/5432/9759/22916/817/207/5436/11140/5245/2099/6934/7529/5594/208/4609/5879/6233/57670/5595/4193/1488/805/79109 66 Human_herpesvirus_6B R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 30/678 92/10654 2.4014059792133963e-14 3.7822144172610993e-13 2.1895172163416263e-13 672/1017/6119/6118/1432/11200/545/472/8851/5300/580/6117/11073/9156/84126/1459/890/1111/1020/7157/8900/1457/6790/641/22974/9212/8148/6233/4193/1263 30 Human_herpesvirus_6B R-HSA-68877 Mitotic Prometaphase 45/678 200/10654 4.2734155751993744e-14 6.63308417541816e-13 3.8398806617733517e-13 701/7514/348995/81565/22995/79023/9133/1062/5518/699/57122/64105/5903/5347/113130/54908/332/440145/3320/55143/64151/891/7531/10142/5501/1459/1058/11190/8655/991/4085/10733/1457/55746/983/7532/140735/4751/9212/11004/1063/23279/5577/79902/5566 45 Human_herpesvirus_6B R-HSA-5663205 Infectious disease 66/678 383/10654 5.143576777110993e-14 7.86967246897982e-13 4.555739431155452e-13 2962/10898/7514/1025/23165/9883/9972/348995/2963/6202/79023/5437/8812/6917/57122/5441/5434/23636/5440/5903/8065/23225/10197/3921/160/8021/5438/9146/3320/10762/808/5431/55706/7175/129401/23511/5435/4686/9631/27183/1499/5433/2547/801/53371/5439/5430/5432/55746/22916/8086/5436/8480/6173/23279/4927/9688/11224/8148/30011/5879/6233/805/8106/79902/6844 66 Human_herpesvirus_6B R-HSA-68875 Mitotic Prophase 36/678 142/10654 3.5675394747653153e-13 5.381457433061483e-12 3.11531616106267e-12 23165/9883/9972/348995/79023/9133/5518/57122/23636/55844/5903/5347/23225/8021/7443/10762/55706/7175/129401/23511/9631/84930/891/53371/55746/983/7112/8086/64900/8480/5594/23279/4927/9688/5595/79902 36 Human_herpesvirus_6B R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 22/678 54/10654 3.882407557359426e-13 5.775081241572146e-12 3.34318428550395e-12 10450/56949/5437/6917/5441/5434/5440/5438/9716/5431/8450/5435/5433/27339/5439/10987/5430/5432/91603/5436/6233/51138 22 Human_herpesvirus_6B R-HSA-1538133 G0 and Early G1 16/678 27/10654 4.1113388065673026e-13 6.031840906621344e-12 3.491822000098257e-12 7153/898/1017/9134/990/5934/1874/993/7027/890/8900/1859/983/5933/5111/4609 16 Human_herpesvirus_6B R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 24/678 65/10654 4.336662430980108e-13 6.2764398156482375e-012 3.633419874604956e-12 10450/6119/6118/56949/5437/6917/5441/5434/5440/5438/9716/6117/5431/8450/5435/5433/27339/5439/5430/5432/91603/5436/5111/6233 24 Human_herpesvirus_6B R-HSA-2262752 Cellular responses to stress 74/678 479/10654 4.576164111478455e-13 6.534762351191234e-12 3.782962332155523e-12 898/1017/23165/6119/7014/3091/830/6118/9883/9972/1432/348995/815/545/25913/79023/472/57122/9134/23636/1019/5903/5601/23225/23411/10197/11065/8021/4343/3320/8726/6117/10762/8881/55706/7175/23512/1021/129401/23511/9631/3312/7531/7027/890/53371/816/8655/2146/9531/7157/8453/5970/8900/55746/817/8086/140735/832/6045/10963/9550/22824/8480/5594/829/23279/4927/9688/3308/6233/5595/4193/79902 74 Human_herpesvirus_6B R-HSA-6782135 Dual incision in TC-NER 24/678 66/10654 6.412601368344476e-13 9.036705349338071e-12 5.231332695228389e-12 10450/6119/6118/56949/5437/6917/5441/5434/5440/5438/9716/6117/5431/8450/5435/5433/27339/5439/5430/5432/91603/5436/5111/6233 24 Human_herpesvirus_6B R-HSA-8953897 Cellular responses to external stimuli 75/678 493/10654 6.971637679137074e-13 9.696914226436111e-12 5.61352644294154e-12 898/1017/23165/6119/7014/3091/830/6118/9883/9972/1432/348995/815/545/25913/79023/472/57122/9134/23636/1019/5903/5601/23225/23411/10197/11065/8021/4343/3320/8726/6117/4520/10762/8881/55706/7175/23512/1021/129401/23511/9631/3312/7531/7027/890/53371/816/8655/2146/9531/7157/8453/5970/8900/55746/817/8086/140735/832/6045/10963/9550/22824/8480/5594/829/23279/4927/9688/3308/6233/5595/4193/79902 75 Human_herpesvirus_6B R-HSA-5633007 Regulation of TP53 Activity 38/678 160/10654 7.162991718930614e-13 9.835338629454726e-12 5.69366008427818e-12 672/1017/6119/6118/5170/1432/11200/545/5518/472/8851/5300/580/6117/11073/9156/84126/1459/890/1111/1020/7157/1107/8900/1457/983/207/6790/641/22974/9212/208/1108/8148/6233/4193/79109/1263 38 Human_herpesvirus_6B R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 26/678 79/10654 1.0296117948580758e-12 1.395840800370885e-11 8.080497630531735e-12 10450/6119/6118/56949/5437/6917/5441/5434/5440/5438/9716/6117/5431/8450/5435/5433/27339/5439/10987/5430/5432/91603/5436/5111/6233/51138 26 Human_herpesvirus_6B R-HSA-69275 G2/M Transition 42/678 196/10654 1.7590230101072499e-12 2.3548920547810806e-11 1.3632428328331187e-11 8454/28227/7514/1017/9088/22995/9133/5518/994/5347/23291/10197/440145/3320/2305/995/891/7531/51512/993/10142/7465/890/4659/11190/4218/8655/5520/7157/10733/8900/983/7532/6790/22974/4751/3161/5500/1063/5577/6233/5566 42 Human_herpesvirus_6B R-HSA-190236 Signaling by FGFR 27/678 87/10654 1.848319970929731e-12 2.443889739340422e-11 1.4147634345388065e-11 2962/3178/2963/5437/5518/5441/5434/5440/4670/6464/5438/5431/3845/5435/4686/5433/5439/3185/5430/5432/22916/5436/5725/5594/6233/5595/3187 27 Human_herpesvirus_6B R-HSA-72086 mRNA Capping 16/678 29/10654 1.8970359852762334e-12 2.477714073452251e-11 1.434344281550323e-11 2962/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 16 Human_herpesvirus_6B R-HSA-453274 Mitotic G2-G2/M phases 42/678 198/10654 2.512713465730804e-12 3.242308580479146e-11 1.8769666852446972e-11 8454/28227/7514/1017/9088/22995/9133/5518/994/5347/23291/10197/440145/3320/2305/995/891/7531/51512/993/10142/7465/890/4659/11190/4218/8655/5520/7157/10733/8900/983/7532/6790/22974/4751/3161/5500/1063/5577/6233/5566 42 Human_herpesvirus_6B R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 23/678 65/10654 3.789714702296564e-12 4.831886245428119e-11 2.7971703755046074e-11 672/2962/1025/2963/545/5437/8812/6917/472/5441/5434/5440/4436/5438/5431/5435/5433/5439/1111/5430/7157/5432/5436 23 Human_herpesvirus_6B R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 22/678 61/10654 7.198014068332961e-12 9.06949772609953e-11 5.250316143960514e-11 10097/10092/4644/4650/2209/917/3320/71/10095/2214/2212/10093/10109/4627/10552/4620/10094/4641/5594/5879/5595/10096 22 Human_herpesvirus_6B R-HSA-453279 Mitotic G1-G1/S phases 35/678 149/10654 8.270038074155304e-12 1.0299082299325966e-10 5.962120472065452e-11 51053/8454/28227/7153/898/1017/6119/6118/4173/5518/9134/1019/10197/8318/6117/990/5934/1021/1874/891/993/7027/7465/890/5520/8900/1859/983/207/5933/5111/208/4609/6233/55388 35 Human_herpesvirus_6B R-HSA-167287 HIV elongation arrest and recovery 17/678 36/10654 1.0392502794771376e-11 1.2648148287727436e-10 7.321990605407107e-11 2962/1025/2963/5437/8812/6917/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 17 Human_herpesvirus_6B R-HSA-167290 Pausing and recovery of HIV elongation 17/678 36/10654 1.0392502794771376e-11 1.2648148287727436e-10 7.321990605407107e-11 2962/1025/2963/5437/8812/6917/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 17 Human_herpesvirus_6B R-HSA-69481 G2/M Checkpoints 37/678 168/10654 1.6204262719709783e-11 1.9499736373942896e-10 1.1288362793505693e-10 672/1017/7533/9088/2810/6119/6118/4173/11200/545/9133/472/10197/7534/8318/580/6117/990/11073/995/9156/84126/891/7531/51512/993/7465/1111/7157/983/7532/10971/641/8924/7529/6233/55388 37 Human_herpesvirus_6B R-HSA-141424 Amplification of signal from the kinetochores 27/678 96/10654 2.444778940202222e-11 2.8773167526995387e-10 1.6656735636542614e-10 701/7514/348995/81565/79023/1062/5518/699/57122/64105/5903/5347/54908/332/55143/5501/1058/8655/991/4085/55746/140735/9212/11004/1063/23279/79902 27 Human_herpesvirus_6B R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 27/678 96/10654 2.444778940202222e-11 2.8773167526995387e-10 1.6656735636542614e-10 701/7514/348995/81565/79023/1062/5518/699/57122/64105/5903/5347/54908/332/55143/5501/1058/8655/991/4085/55746/140735/9212/11004/1063/23279/79902 27 Human_herpesvirus_6B R-HSA-113418 Formation of the Early Elongation Complex 16/678 33/10654 2.563323735291745e-11 2.920552894146233e-10 1.690702889234981e-10 2962/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 16 Human_herpesvirus_6B R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 16/678 33/10654 2.563323735291745e-11 2.920552894146233e-10 1.690702889234981e-10 2962/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 16 Human_herpesvirus_6B R-HSA-1839126 FGFR2 mutant receptor activation 16/678 33/10654 2.563323735291745e-11 2.920552894146233e-10 1.690702889234981e-10 2962/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 16 Human_herpesvirus_6B R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 19/678 48/10654 2.924472419142863e-11 3.296957853581059e-10 1.9086030524932373e-10 2962/1025/2963/5437/8812/6917/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 19 Human_herpesvirus_6B R-HSA-5663220 RHO GTPases Activate Formins 33/678 140/10654 2.982937760479671e-11 3.327839939035133e-10 1.9264806369764542e-10 701/7514/23380/388/348995/81565/79023/1062/5518/699/57122/64105/5903/5347/387/54908/332/71/55143/5501/1058/8655/991/4085/55746/140735/9212/389/11004/1063/23279/5879/79902 33 Human_herpesvirus_6B R-HSA-2500257 Resolution of Sister Chromatid Cohesion 31/678 126/10654 3.6822052904862085e-11 4.065610171248174e-10 2.3535745155685045e-10 701/7514/348995/81565/79023/9133/1062/5518/699/57122/64105/5903/5347/113130/54908/332/55143/891/5501/1058/8655/991/4085/55746/983/140735/9212/11004/1063/23279/79902 31 Human_herpesvirus_6B R-HSA-69618 Mitotic Spindle Checkpoint 29/678 112/10654 4.1534253101735794e-11 4.53910051754684e-10 2.6276772370485913e-10 701/7514/348995/81565/79023/1062/5518/699/57122/64105/5903/5347/11065/54908/332/8881/55143/5501/1058/8655/991/4085/55746/140735/9212/11004/1063/23279/79902 29 Human_herpesvirus_6B R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 16/678 34/10654 4.5589236368412725e-11 4.882607215057004e-10 2.826532654841589e-10 2962/1025/2963/5437/6917/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 16 Human_herpesvirus_6B R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 16/678 34/10654 4.5589236368412725e-11 4.882607215057004e-10 2.826532654841589e-10 2962/1025/2963/5437/6917/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 16 Human_herpesvirus_6B R-HSA-112382 Formation of RNA Pol II elongation complex 21/678 61/10654 6.042936975225522e-11 6.345083823986798e-10 3.673157769254729e-10 2962/1025/2963/5437/8812/6917/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436/80349/123169 21 Human_herpesvirus_6B R-HSA-75955 RNA Polymerase II Transcription Elongation 21/678 61/10654 6.042936975225522e-11 6.345083823986798e-10 3.673157769254729e-10 2962/1025/2963/5437/8812/6917/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436/80349/123169 21 Human_herpesvirus_6B R-HSA-72306 tRNA processing 28/678 107/10654 6.881540236095224e-11 7.155465624133965e-10 4.142286355707805e-10 10898/29894/23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/10978/8086/1478/8480/23279/4927/9688/79902 28 Human_herpesvirus_6B R-HSA-162909 Host Interactions of HIV factors 31/678 129/10654 7.048236243285296e-11 7.25832790053707e-10 4.201833145035465e-10 7514/1025/23165/9883/9972/348995/79023/57122/23636/5903/8065/23225/10197/160/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/5879/6233/79902 31 Human_herpesvirus_6B R-HSA-69206 G1/S Transition 31/678 131/10654 1.073376464782758e-10 1.094843994078413e-9 6.338032458717239e-10 51053/8454/28227/898/1017/6119/6118/4173/5518/9134/1019/10197/8318/6117/990/5934/1874/891/993/7027/7465/890/8900/983/207/5933/5111/208/4609/6233/55388 31 Human_herpesvirus_6B R-HSA-69473 G2/M DNA damage checkpoint 26/678 95/10654 1.1216771502783709e-10 1.133317196177486e-9 6.560753143137641e-10 672/7533/2810/6119/6118/11200/545/472/7534/580/6117/11073/995/9156/84126/891/7531/7465/1111/7157/983/7532/10971/641/8924/7529 26 Human_herpesvirus_6B R-HSA-167169 HIV Transcription Elongation 18/678 46/10654 1.2262963434027535e-10 1.2049205355819716e-9 6.975263604676213e-10 2962/1025/2963/5437/6917/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 18 Human_herpesvirus_6B R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 18/678 46/10654 1.2262963434027535e-10 1.2049205355819716e-9 6.975263604676213e-10 2962/1025/2963/5437/6917/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 18 Human_herpesvirus_6B R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 18/678 46/10654 1.2262963434027535e-10 1.2049205355819716e-9 6.975263604676213e-10 2962/1025/2963/5437/6917/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 18 Human_herpesvirus_6B R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 14/678 27/10654 1.4486446142836291e-10 1.3977462899979882e-9 8.09152847617883e-10 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 14 Human_herpesvirus_6B R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 14/678 27/10654 1.4486446142836291e-10 1.3977462899979882e-9 8.09152847617883e-10 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 14 Human_herpesvirus_6B R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 67/678 473/10654 3.2170820418738473e-10 3.0763347025418666e-9 1.7808847017515942e-9 2962/5898/1003/3178/5170/1432/51741/2963/5437/5518/5441/5434/5440/4670/387/8065/6464/1956/8851/4914/160/5438/9146/3320/808/5431/71/3845/5435/4686/1499/2065/5433/6300/801/5439/1111/1020/3630/5567/3185/5430/2066/5432/22916/207/4734/5436/5725/11140/10768/9550/10413/2099/7529/5594/208/30011/5879/6233/5568/5595/805/3187/79109/7074/5566 67 Human_herpesvirus_6B R-HSA-5655253 Signaling by FGFR2 in disease 17/678 43/10654 3.337566105654918e-10 3.163303804563201e-9 1.831230960624822e-9 2962/2963/5437/5441/5434/5440/5438/5431/3845/5435/4686/5433/5439/5430/5432/22916/5436 17 Human_herpesvirus_6B R-HSA-73894 DNA Repair 53/678 334/10654 4.33660060242761e-10 4.074122144912255e-9 2.3585020820220333e-9 10450/672/1017/6119/7014/6118/22976/11200/545/25913/56949/5437/6917/472/5441/5434/5440/55247/7706/4436/221120/151987/5438/580/9716/6117/5431/11073/8450/5435/9156/84126/5433/322/328/27339/2547/890/5439/1111/10987/5430/7157/8900/5432/91603/5436/641/5111/8924/6233/51138/7517 53 Human_herpesvirus_6B R-HSA-913531 Interferon Signaling 38/678 199/10654 7.254550434496947e-10 6.756194361170635e-9 3.911148929902703e-9 23165/9883/9972/348995/2209/815/79023/57122/23636/5903/23225/7706/5300/8021/9775/10762/55706/7175/129401/9470/23511/9631/10612/53371/816/55746/2316/817/8086/4734/8480/9830/23279/4927/9688/6233/5595/79902 38 Human_herpesvirus_6B R-HSA-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase 10/678 14/10654 8.100168516593233e-10 7.47869007006151e-9 4.329400414041211e-9 5576/5573/808/5575/801/5567/5577/5568/805/5566 10 Human_herpesvirus_6B R-HSA-114452 Activation of BH3-only proteins 14/678 30/10654 8.776885933735452e-10 8.034226354727067e-9 4.650999383688872e-9 7533/2810/7534/7531/7027/8655/7157/7532/90427/207/10971/140735/7529/208 14 Human_herpesvirus_6B R-HSA-180024 DARPP-32 events 13/678 26/10654 1.2057667621164937e-9 1.0943866120565803e-8 6.335384682307002e-9 5518/5576/5573/808/5575/801/1020/5567/5499/5577/5568/805/5566 13 Human_herpesvirus_6B R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 11/678 18/10654 1.3514534607799017e-9 1.2163081147019115e-8 7.0411860981810015e-9 2810/5934/995/1874/891/7027/7157/983/6790/5933/5111 11 Human_herpesvirus_6B R-HSA-6802957 Oncogenic MAPK signaling 21/678 71/10654 1.4813414033132734e-9 1.3220972024570966e-8 7.653597250451912e-9 409/8826/815/8805/4140/808/71/3845/408/10142/801/4763/816/8844/817/5245/7529/5594/57670/5595/805 21 Human_herpesvirus_6B R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 17/678 47/10654 1.7068834064804316e-9 1.474251716403663e-8 8.534417032402158e-9 409/8826/815/4140/808/71/3845/408/801/816/8844/817/5245/7529/5594/5595/805 17 Human_herpesvirus_6B R-HSA-6802949 Signaling by RAS mutants 17/678 47/10654 1.7068834064804316e-9 1.474251716403663e-8 8.534417032402158e-9 409/8826/815/4140/808/71/3845/408/801/816/8844/817/5245/7529/5594/5595/805 17 Human_herpesvirus_6B R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 17/678 47/10654 1.7068834064804316e-9 1.474251716403663e-8 8.534417032402158e-9 409/8826/815/4140/808/71/3845/408/801/816/8844/817/5245/7529/5594/5595/805 17 Human_herpesvirus_6B R-HSA-9649948 Signaling downstream of RAS mutants 17/678 47/10654 1.7068834064804316e-9 1.474251716403663e-8 8.534417032402158e-9 409/8826/815/4140/808/71/3845/408/801/816/8844/817/5245/7529/5594/5595/805 17 Human_herpesvirus_6B R-HSA-109606 Intrinsic Pathway for Apoptosis 18/678 53/10654 1.8419163168526739e-9 1.578153900279371e-8 9.135904931589264e-9 7533/2810/598/7534/708/7531/7027/8655/7157/7532/90427/207/10971/140735/7529/5594/208/5595 18 Human_herpesvirus_6B R-HSA-264876 Insulin processing 13/678 27/10654 2.190890327041186e-9 1.857766424587599e-8 1.0754576874363322e-8 4644/55763/25924/54536/60412/5873/10640/3630/11336/149371/55770/23265/6844 13 Human_herpesvirus_6B R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 23/678 86/10654 2.2029536500711963e-9 1.857766424587599e-8 1.0754576874363322e-8 10097/10092/4644/4650/2209/917/3320/71/10095/2214/2212/10093/10109/4627/10552/10768/4620/10094/4641/5594/5879/5595/10096 23 Human_herpesvirus_6B R-HSA-6807505 RNA polymerase II transcribes snRNA genes 21/678 74/10654 3.4177326399466395e-9 2.8596809823303524e-8 1.655464247474154e-8 2962/1025/2963/5437/8812/5441/5434/5440/51593/84524/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436/51585 21 Human_herpesvirus_6B R-HSA-68882 Mitotic Anaphase 37/678 201/10654 3.5117311776484398e-9 2.9155535591174258e-8 1.6878087830558393e-8 701/7514/348995/81565/79023/1062/5518/699/57122/64105/5903/5347/113130/10197/11065/54908/332/7443/8881/55143/5501/1058/8655/991/5520/4085/55746/7112/140735/9212/11004/9232/1063/23279/6233/9700/79902 37 Human_herpesvirus_6B R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 17/678 49/10654 3.5875650127817196e-9 2.9356486163652828e-8 1.6994417760471292e-8 898/1017/2810/9134/5934/995/1874/891/7027/890/7157/8900/983/6790/5933/5111/1263 17 Human_herpesvirus_6B R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 23/678 88/10654 3.5907560106802245e-9 2.9356486163652828e-8 1.6994417760471292e-8 8454/22995/9133/5518/5347/23291/3320/891/7531/10142/4659/11190/4218/8655/10733/983/7532/6790/4751/5500/5577/6233/5566 23 Human_herpesvirus_6B R-HSA-2555396 Mitotic Metaphase and Anaphase 37/678 202/10654 4.045111298856402e-9 3.282056212935763e-8 1.8999765191598253e-8 701/7514/348995/81565/79023/1062/5518/699/57122/64105/5903/5347/113130/10197/11065/54908/332/7443/8881/55143/5501/1058/8655/991/5520/4085/55746/7112/140735/9212/11004/9232/1063/23279/6233/9700/79902 37 Human_herpesvirus_6B R-HSA-5696398 Nucleotide Excision Repair 26/678 111/10654 4.393699729746911e-9 3.538084519217249e-8 2.048190851460966e-8 10450/6119/6118/56949/5437/6917/5441/5434/5440/5438/9716/6117/5431/8450/5435/5433/27339/5439/10987/5430/5432/91603/5436/5111/6233/51138 26 Human_herpesvirus_6B R-HSA-203927 MicroRNA (miRNA) biogenesis 12/678 24/10654 5.33591224925909e-9 4.2647477753406605e-8 2.4688549212989825e-8 5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 12 Human_herpesvirus_6B R-HSA-1226099 Signaling by FGFR in disease 19/678 63/10654 6.2709053281608486e-9 4.974918227007607e-8 2.8799713358960937e-8 2962/399687/2963/5437/8805/5441/5434/5440/5438/5431/3845/5435/4686/5433/5439/5430/5432/22916/5436 19 Human_herpesvirus_6B R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 13/678 29/10654 6.580057268096451e-9 5.181795098625955e-8 2.9997319898675004e-8 5437/5441/5434/5440/5438/3320/5431/5435/5433/5439/5430/5432/5436 13 Human_herpesvirus_6B R-HSA-674695 RNA Polymerase II Pre-transcription Events 22/678 84/10654 7.543967510392954e-9 5.897510367613762e-8 3.414058289374914e-8 2962/1025/2963/5437/8812/6917/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436/80349/8148/123169 22 Human_herpesvirus_6B R-HSA-5619102 SLC transporter disorders 24/678 99/10654 8.377601474125727e-9 6.501747231006271e-8 3.763849937650689e-8 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Human_herpesvirus_6B R-HSA-167172 Transcription of the HIV genome 20/678 73/10654 1.573831097681554e-8 1.2126425220265785e-7 7.019966047212686e-8 2962/1025/2963/5437/8812/6917/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436/8148 20 Human_herpesvirus_6B R-HSA-6804757 Regulation of TP53 Degradation 14/678 36/10654 1.600703756996326e-8 1.2245383741021894e-7 7.088830923840873e-8 1017/5170/11200/5518/472/890/7157/8900/983/207/208/6233/4193/79109 14 Human_herpesvirus_6B R-HSA-6802952 Signaling by BRAF and RAF fusions 19/678 67/10654 1.939916055367131e-8 1.4735107058852463e-7 8.530127335656888e-8 409/8826/815/8805/4140/808/71/3845/408/10142/801/816/8844/817/7529/5594/57670/5595/805 19 Human_herpesvirus_6B R-HSA-438064 Post NMDA receptor activation events 21/678 81/10654 2.0137397831234126e-8 1.5188135969895598e-7 8.792384968567014e-8 5170/815/5576/5573/808/3845/2890/5575/801/2891/816/5567/2066/817/5594/5577/5879/5568/5595/805/5566 21 Human_herpesvirus_6B R-HSA-6806003 Regulation of TP53 Expression and Degradation 14/678 37/10654 2.4257547170653127e-8 1.8167715398440207e-7 1.0517258213849608e-7 1017/5170/11200/5518/472/890/7157/8900/983/207/208/6233/4193/79109 14 Human_herpesvirus_6B R-HSA-2467813 Separation of Sister Chromatids 34/678 190/10654 3.187024133724072e-8 2.3703491994572788e-7 1.372190946464531e-7 701/7514/348995/81565/79023/1062/5518/699/57122/64105/5903/5347/113130/10197/11065/54908/332/8881/55143/5501/1058/8655/991/4085/55746/140735/9212/11004/9232/1063/23279/6233/9700/79902 34 Human_herpesvirus_6B R-HSA-9006925 Intracellular signaling by second messengers 46/678 305/10654 3.2432527348290394e-8 2.395533571725449e-7 1.3867701348924172e-7 10014/5170/815/5518/1956/10197/5576/5573/4343/8726/808/23512/2100/2065/5575/1459/801/6615/816/3630/5567/2146/5978/7157/1107/2066/1457/23028/817/207/4734/6045/10768/2099/5594/208/1108/5577/5879/6233/5568/5595/4193/805/79109/5566 46 Human_herpesvirus_6B R-HSA-111996 Ca-dependent events 14/678 38/10654 3.6181587687668546e-8 2.654142494074864e-7 1.5364783812571575e-7 815/5576/5573/808/5575/801/816/5567/817/5594/5577/5568/805/5566 14 Human_herpesvirus_6B R-HSA-163615 PKA activation 10/678 19/10654 5.5770461445153845e-8 4.0632764767183514e-7 2.3522235439452643e-7 5576/5573/808/5575/801/5567/5577/5568/805/5566 10 Human_herpesvirus_6B R-HSA-442755 Activation of NMDA receptors and postsynaptic events 22/678 93/10654 5.646458724307526e-8 4.086052225495514e-7 2.365408384507207e-7 5170/815/8573/5576/5573/808/3845/2890/5575/801/2891/816/5567/2066/817/5594/5577/5879/5568/5595/805/5566 22 Human_herpesvirus_6B R-HSA-111447 Activation of BAD and translocation to mitochondria 9/678 15/10654 5.749833457991164e-8 4.132933982220495e-7 2.392548150305048e-7 7533/2810/7534/7531/7532/207/10971/7529/208 9 Human_herpesvirus_6B R-HSA-5625900 RHO GTPases activate CIT 10/678 20/10654 1.0520218635027076e-7 7.424284081829224e-7 4.297904883972101e-7 9055/388/9928/387/4659/4627/4629/5500/389/5879 10 Human_herpesvirus_6B R-HSA-167161 HIV Transcription Initiation 15/678 47/10654 1.0814083256445929e-7 7.424284081829224e-7 4.297904883972101e-7 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/8148 15 Human_herpesvirus_6B R-HSA-167162 RNA Polymerase II HIV Promoter Escape 15/678 47/10654 1.0814083256445929e-7 7.424284081829224e-7 4.297904883972101e-7 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/8148 15 Human_herpesvirus_6B R-HSA-73776 RNA Polymerase II Promoter Escape 15/678 47/10654 1.0814083256445929e-7 7.424284081829224e-7 4.297904883972101e-7 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/8148 15 Human_herpesvirus_6B R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 15/678 47/10654 1.0814083256445929e-7 7.424284081829224e-7 4.297904883972101e-7 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/8148 15 Human_herpesvirus_6B R-HSA-75953 RNA Polymerase II Transcription Initiation 15/678 47/10654 1.0814083256445929e-7 7.424284081829224e-7 4.297904883972101e-7 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/8148 15 Human_herpesvirus_6B R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 15/678 47/10654 1.0814083256445929e-7 7.424284081829224e-7 4.297904883972101e-7 2962/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436/8148 15 Human_herpesvirus_6B R-HSA-156711 Polo-like kinase mediated events 9/678 16/10654 1.2401500897531338e-7 8.459877363857365e-7 4.897407997751228e-7 9088/9133/5347/2305/995/891/993/7465/1063 9 Human_herpesvirus_6B R-HSA-111933 Calmodulin induced events 13/678 36/10654 1.4774224199120627e-7 9.951694413369931e-7 5.761018241166534e-7 815/5576/5573/808/5575/801/816/5567/817/5577/5568/805/5566 13 Human_herpesvirus_6B R-HSA-111997 CaM pathway 13/678 36/10654 1.4774224199120627e-7 9.951694413369931e-7 5.761018241166534e-7 815/5576/5573/808/5575/801/816/5567/817/5577/5568/805/5566 13 Human_herpesvirus_6B R-HSA-1489509 DAG and IP3 signaling 14/678 42/10654 1.5579321097074935e-7 1.0428408059354533e-6 6.036986925116538e-7 815/5576/5573/808/5575/801/816/5567/817/10768/5577/5568/805/5566 14 Human_herpesvirus_6B R-HSA-111931 PKA-mediated phosphorylation of CREB 10/678 21/10654 1.8943228370599227e-7 1.2505417898371165e-6 7.239364236218602e-7 5576/5573/808/5575/801/5567/5577/5568/805/5566 10 Human_herpesvirus_6B R-HSA-5620916 VxPx cargo-targeting to cilium 10/678 21/10654 1.8943228370599227e-7 1.2505417898371165e-6 7.239364236218602e-7 55763/54536/8766/60412/10640/4218/11336/149371/55770/23265 10 Human_herpesvirus_6B R-HSA-8939211 ESR-mediated signaling 36/678 223/10654 1.9032522104897292e-7 1.2505417898371165e-6 7.239364236218602e-7 2962/7514/1025/5170/2963/5437/5441/5434/5440/6464/1956/5438/4343/3320/808/5431/3845/2100/5435/5433/801/5439/1655/5430/2066/5432/861/23028/207/5436/2099/5594/208/4609/5595/805 36 Human_herpesvirus_6B R-HSA-176187 Activation of ATR in response to replication stress 13/678 37/10654 2.1462978501900601e-7 1.401637193630216e-6 8.114052848279497e-7 1017/6119/6118/4173/545/8318/6117/990/995/84126/993/1111/55388 13 Human_herpesvirus_6B R-HSA-5673000 RAF activation 12/678 32/10654 2.774223022842574e-7 1.8007229439178164e-6 1.0424353176741794e-6 815/5518/4140/808/3845/801/816/8844/817/5245/7529/805 12 Human_herpesvirus_6B R-HSA-5625740 RHO GTPases activate PKNs 21/678 95/10654 3.868988578410819e-7 2.4961968478783054e-6 1.4450439268763302e-6 388/7533/2810/5170/29941/387/7534/995/7531/4659/5586/5585/4627/7532/23028/10971/4629/5500/389/7529/5879 21 Human_herpesvirus_6B R-HSA-111367 SLBP independent Processing of Histone Pre-mRNAs 7/678 10/10654 4.1564451208732496e-7 2.665600433805539e-6 1.5431113622403683e-6 6637/6635/6634/4686/22916/6628/6636 7 Human_herpesvirus_6B R-HSA-5218920 VEGFR2 mediated vascular permeability 11/678 29/10654 7.686206054794736e-7 4.899956359931644e-6 2.836576044031391e-6 1003/5170/3320/808/1499/801/207/208/5879/805/79109 11 Human_herpesvirus_6B R-HSA-112043 PLC beta mediated events 15/678 54/10654 8.193129966408328e-7 5.19221431599013e-6 3.005763656315481e-6 815/5576/5573/808/5575/801/816/5567/817/10768/5594/5577/5568/805/5566 15 Human_herpesvirus_6B R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 9/678 19/10654 8.415797205870504e-7 5.301952239698417e-6 3.0692907456704196e-6 7153/990/5934/1874/993/7027/5933/5111/4609 9 Human_herpesvirus_6B R-HSA-5627123 RHO GTPases activate PAKs 10/678 24/10654 8.839847711426999e-7 5.536536198209542e-6 3.205090983090491e-6 2017/808/801/4659/4627/2316/4629/5500/5879/805 10 Human_herpesvirus_6B R-HSA-69242 S Phase 28/678 161/10654 9.58690625265089e-7 5.969521277086687e-6 3.4557452771183445e-6 8454/898/1017/6119/6118/4173/9134/1019/994/113130/10197/11065/8318/6117/8881/990/5934/1874/993/7027/7465/890/8900/207/5111/208/4609/6233 28 Human_herpesvirus_6B R-HSA-112040 G-protein mediated events 15/678 55/10654 1.0612280109689609e-6 6.569798842472584e-6 3.8032448948020566e-6 815/5576/5573/808/5575/801/816/5567/817/10768/5594/5577/5568/805/5566 15 Human_herpesvirus_6B R-HSA-77588 SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs 7/678 11/10654 1.080152186322063e-6 6.610531380291025e-6 3.82682488868388e-6 6637/6635/6634/4686/22916/6628/6636 7 Human_herpesvirus_6B R-HSA-9614399 Regulation of localization of FOXO transcription factors 7/678 11/10654 1.080152186322063e-6 6.610531380291025e-6 3.82682488868388e-6 2810/7534/7532/207/10971/7529/208 7 Human_herpesvirus_6B R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 13/678 42/10654 1.1425888367916358e-6 6.952912751158192e-6 4.025028856879626e-6 672/6119/6118/545/472/580/6117/11073/9156/84126/1111/641/7517 13 Human_herpesvirus_6B R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 12/678 36/10654 1.2141265240770555e-6 7.346494391449301e-6 4.252872570213415e-6 10097/10092/71/10095/10093/10109/10552/10094/5594/5879/5595/10096 12 Human_herpesvirus_6B R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 19/678 86/10654 1.3942108222931634e-6 8.341898271932838e-6 4.8291101107360976e-6 701/8454/1017/5347/10197/11065/8881/891/890/991/4085/8900/983/8556/6790/4751/9212/9232/6233 19 Human_herpesvirus_6B R-HSA-453276 Regulation of mitotic cell cycle 19/678 86/10654 1.3942108222931634e-6 8.341898271932838e-6 4.8291101107360976e-6 701/8454/1017/5347/10197/11065/8881/891/890/991/4085/8900/983/8556/6790/4751/9212/9232/6233 19 Human_herpesvirus_6B R-HSA-8856828 Clathrin-mediated endocytosis 26/678 146/10654 1.4705501283365976e-6 8.749773263602757e-6 5.06522821982606e-6 10097/409/1080/10092/29978/2017/1956/160/917/9146/71/408/3312/10093/10987/10109/10552/10094/4738/1212/30011/6233/1601/51138/10096/6844 26 Human_herpesvirus_6B R-HSA-8854518 AURKA Activation by TPX2 17/678 73/10654 2.3051699432190032e-6 1.3639983476174322e-5 7.896162236440785e-6 22995/5518/5347/3320/7531/10142/11190/8655/10733/983/7532/6790/22974/4751/3161/5577/5566 17 Human_herpesvirus_6B R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 12/678 39/10654 3.177898336629035e-6 1.8700709442470862e-5 1.0825807520384627e-5 672/6119/6118/545/472/580/6117/11073/9156/84126/1111/641 12 Human_herpesvirus_6B R-HSA-4420097 VEGFA-VEGFR2 Pathway 20/678 99/10654 3.265623716532078e-6 1.9111928963966424e-5 1.1063861771857314e-5 1003/5170/1432/387/3320/808/71/3845/1499/6300/801/5567/207/10768/208/5879/5568/805/79109/5566 20 Human_herpesvirus_6B R-HSA-69205 G1/S-Specific Transcription 10/678 28/10654 4.684176418750775e-6 2.7264961654793915e-5 1.578363793274718e-5 898/8318/990/5934/1874/7027/8900/983/5933/5111 10 Human_herpesvirus_6B R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 18/678 85/10654 5.006072486733164e-6 2.8981100720493075e-5 1.677710779337601e-5 8454/898/1017/9134/1019/994/10197/5934/1874/993/7027/7465/890/8900/207/208/4609/6233 18 Human_herpesvirus_6B R-HSA-5619115 Disorders of transmembrane transporters 28/678 176/10654 5.84573182286078e-6 3.366010098002094e-5 1.9485772742869266e-5 1080/23165/9883/9972/348995/79023/57122/23636/5903/23225/10197/8021/10762/55706/7175/129401/23511/9631/53371/10956/55746/8086/8480/23279/4927/9688/6233/79902 28 Human_herpesvirus_6B R-HSA-3928662 EPHB-mediated forward signaling 12/678 42/10654 7.529151858339391e-6 4.312150609776197e-5 2.49629633805905e-5 10097/10092/387/71/10095/10093/10109/10552/10094/5879/7074/10096 12 Human_herpesvirus_6B R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 10/678 30/10654 9.545313503753061e-6 5.4377823204891106e-5 3.1479225384717543e-5 5170/815/808/3845/801/816/817/5594/5595/805 10 Human_herpesvirus_6B R-HSA-170834 Signaling by TGF-beta Receptor Complex 16/678 73/10654 1.0509082927361044e-5 5.9551469921712585e-5 3.447424029081401e-5 22938/7514/57154/1025/8812/387/57530/1874/7027/5501/5499/4738/5933/5500/4609/6233 16 Human_herpesvirus_6B R-HSA-194138 Signaling by VEGF 20/678 107/10654 1.1248534239778885e-5 6.340621142527992e-5 3.670574330875215e-5 1003/5170/1432/387/3320/808/71/3845/1499/6300/801/5567/207/10768/208/5879/5568/805/79109/5566 20 Human_herpesvirus_6B R-HSA-5685938 HDR through Single Strand Annealing (SSA) 11/678 37/10654 1.1879608567088769e-5 6.661288364058677e-5 3.856208016541904e-5 672/6119/6118/545/472/580/6117/11073/9156/84126/641 11 Human_herpesvirus_6B R-HSA-9620244 Long-term potentiation 9/678 25/10654 1.3156916856820145e-5 7.339092684194987e-5 4.248587735014839e-5 815/808/2890/801/2891/816/2066/817/805 9 Human_herpesvirus_6B R-HSA-111885 Opioid Signalling 18/678 91/10654 1.3673306536597215e-5 7.587622435593584e-5 4.392461167197033e-5 815/5518/5576/5573/808/5575/801/1020/816/5567/817/10768/5499/5594/5577/5568/805/5566 18 Human_herpesvirus_6B R-HSA-69202 Cyclin E associated events during G1/S transition 17/678 83/10654 1.4595639552688044e-5 8.057695856148914e-5 4.664585836426076e-5 8454/898/1017/9134/1019/10197/5934/1874/993/7027/7465/890/8900/207/208/4609/6233 17 Human_herpesvirus_6B R-HSA-5685942 HDR through Homologous Recombination (HRR) 15/678 67/10654 1.5074904417241938e-5 8.279601349162111e-5 4.793046532661539e-5 672/6119/6118/545/472/580/6117/11073/9156/84126/1111/641/5111/6233/7517 15 Human_herpesvirus_6B R-HSA-983231 Factors involved in megakaryocyte development and platelet production 26/678 168/10654 2.066392526611098e-5 1.1291359163267786e-4 6.536547788259597e-5 1017/830/3832/10112/10749/1062/24137/5576/56992/5573/9493/5575/7465/1020/5567/7157/23303/23028/832/11004/829/5577/5879/5568/3835/5566 26 Human_herpesvirus_6B R-HSA-5683057 MAPK family signaling cascades 38/678 294/10654 2.20171921736147e-5 1.1969752699462612e-4 6.92926860286351e-5 409/7514/8826/815/9462/5518/6464/1956/10197/6711/4140/4343/808/8452/71/3845/408/2065/801/4763/816/5567/8844/2066/983/817/8556/5245/7529/5594/4609/5879/6233/5568/5595/805/6709/5566 38 Human_herpesvirus_6B R-HSA-2514853 Condensation of Prometaphase Chromosomes 6/678 11/10654 2.2773954508392556e-5 1.231863902953961e-4 7.1312382804057507e-005 9133/64151/891/1459/1457/983 6 Human_herpesvirus_6B R-HSA-8848021 Signaling by PTK6 13/678 54/10654 2.438431676370693e-5 1.3057801626965062e-4 7.559138196749149e-5 898/1017/3091/1019/387/1956/6421/3845/2065/2066/207/5879/6233 13 Human_herpesvirus_6B R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 13/678 54/10654 2.438431676370693e-5 1.3057801626965062e-4 7.559138196749149e-5 898/1017/3091/1019/387/1956/6421/3845/2065/2066/207/5879/6233 13 Human_herpesvirus_6B R-HSA-5693607 Processing of DNA double-strand break ends 18/678 98/10654 3.913694516078457e-5 2.0853566302089687e-4 1.2072092537157431e-4 672/1017/6119/6118/545/472/151987/580/6117/11073/9156/84126/890/1111/8900/641/8924/6233 18 Human_herpesvirus_6B R-HSA-111932 CaMK IV-mediated phosphorylation of CREB 6/678 12/10654 4.309800815429742e-5 2.2850478580818087e-4 1.322810151270515e-4 815/808/801/816/817/805 6 Human_herpesvirus_6B R-HSA-164378 PKA activation in glucagon signalling 7/678 17/10654 4.53837557351942e-5 2.3943843543050732e-4 1.3861048549665227e-4 5576/5573/5575/5567/5577/5568/5566 7 Human_herpesvirus_6B R-HSA-5693532 DNA Double-Strand Break Repair 25/678 166/10654 4.732809550345928e-5 2.484725013931612e-4 1.4384029025561154e-4 672/1017/6119/6118/22976/11200/545/472/151987/580/6117/11073/9156/84126/322/2547/890/1111/7157/8900/641/5111/8924/6233/7517 25 Human_herpesvirus_6B R-HSA-8863795 Downregulation of ERBB2 signaling 9/678 29/10654 5.121940671263397e-5 2.67590168727956e-4 1.5490747396016126e-4 8065/1956/3320/2065/2066/207/11140/208/6233 9 Human_herpesvirus_6B R-HSA-1227986 Signaling by ERBB2 12/678 50/10654 5.162998214455119e-5 2.684257809554093e-4 1.5539120839622205e-4 387/8065/6464/1956/3320/3845/2065/2066/207/11140/208/6233 12 Human_herpesvirus_6B R-HSA-438066 Unblocking of NMDA receptors, glutamate binding and activation 8/678 23/10654 5.372719764942761e-5 2.7797984870790807e-4 1.60922041268817e-4 815/808/2890/801/2891/816/817/805 8 Human_herpesvirus_6B R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 11/678 43/10654 5.626945028553828e-5 2.89733563729863e-4 1.677262460434314e-4 359/4645/5576/22841/5573/8766/5575/5567/5577/5568/5566 11 Human_herpesvirus_6B R-HSA-390522 Striated Muscle Contraction 10/678 36/10654 5.698510496312692e-5 2.906240353119473e-4 1.682417384625652e-4 7168/7169/7171/4633/7111/29766/70/29767/29765/7170 10 Human_herpesvirus_6B R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 10/678 36/10654 5.698510496312692e-5 2.906240353119473e-4 1.682417384625652e-4 409/8826/4140/71/3845/408/8844/7529/5594/5595 10 Human_herpesvirus_6B R-HSA-2682334 EPH-Ephrin signaling 17/678 92/10654 5.89376093047641e-5 2.9915724912512963e-4 1.7318160080072865e-4 10097/10092/387/160/71/10095/10093/10109/6386/4627/10552/4629/10094/1212/5879/7074/10096 17 Human_herpesvirus_6B R-HSA-69231 Cyclin D associated events in G1 11/678 44/10654 7.07711512380889e-5 3.5424907735635684e-4 2.0507416242851662e-4 8454/28227/5518/1019/5934/1021/1874/7027/5520/5933/6233 11 Human_herpesvirus_6B R-HSA-69236 G1 Phase 11/678 44/10654 7.07711512380889e-5 3.5424907735635684e-4 2.0507416242851662e-4 8454/28227/5518/1019/5934/1021/1874/7027/5520/5933/6233 11 Human_herpesvirus_6B R-HSA-9018519 Estrogen-dependent gene expression 23/678 150/10654 7.096138021580882e-5 3.5424907735635684e-4 2.0507416242851662e-4 2962/1025/2963/5437/5441/5434/5440/5438/4343/3320/5431/5435/5433/5439/1655/5430/2066/5432/861/23028/5436/2099/4609 23 Human_herpesvirus_6B R-HSA-5617833 Cilium Assembly 28/678 201/10654 7.111442729375978e-5 3.5424907735635684e-4 2.0507416242851662e-4 55763/22995/55112/5518/5347/3320/56623/54536/8766/7531/10142/22832/60412/10640/11190/4218/8655/10733/11336/983/7532/140735/4751/149371/5577/55770/23265/5566 28 Human_herpesvirus_6B R-HSA-9009391 Extra-nuclear estrogen signaling 15/678 77/10654 8.486524155437956e-5 4.207901560404653e-4 2.4359467483201544e-4 7514/5170/6464/1956/3320/808/3845/2100/801/207/2099/5594/208/5595/805 15 Human_herpesvirus_6B R-HSA-8943724 Regulation of PTEN gene transcription 13/678 61/10654 9.559674248850834e-5 4.7181618066908956e-4 2.731335499671667e-4 10014/8726/23512/6615/2146/5978/7157/1107/23028/6045/5594/1108/5595 13 Human_herpesvirus_6B R-HSA-380259 Loss of Nlp from mitotic centrosomes 14/678 70/10654 1.0793604828621191e-4 5.278516333996938e-4 3.0557237414361365e-4 22995/5518/5347/3320/7531/10142/11190/8655/10733/983/7532/4751/5577/5566 14 Human_herpesvirus_6B R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 14/678 70/10654 1.0793604828621191e-4 5.278516333996938e-4 3.0557237414361365e-4 22995/5518/5347/3320/7531/10142/11190/8655/10733/983/7532/4751/5577/5566 14 Human_herpesvirus_6B R-HSA-71387 Metabolism of carbohydrates 36/678 295/10654 1.2038176088370829e-4 5.860402995747799e-4 3.39257689763178e-4 23165/9883/9972/348995/79023/2023/5518/51084/57122/23636/5903/23225/8021/10762/808/55706/7175/129401/23511/9631/801/53371/5230/5567/55746/8086/8480/3161/23279/4927/9688/6233/5568/805/79902/5566 36 Human_herpesvirus_6B R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 6/678 14/10654 1.2543132727261934e-4 5.997185335222112e-4 3.4717599512957143e-4 9133/5347/891/983/5594/5595 6 Human_herpesvirus_6B R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 6/678 14/10654 1.2543132727261934e-4 5.997185335222112e-4 3.4717599512957143e-4 6119/6118/4436/6117/9156/5111 6 Human_herpesvirus_6B R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 6/678 14/10654 1.2543132727261934e-4 5.997185335222112e-4 3.4717599512957143e-4 6119/6118/4436/6117/9156/5111 6 Human_herpesvirus_6B R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 6/678 14/10654 1.2543132727261934e-4 5.997185335222112e-4 3.4717599512957143e-4 898/1017/9134/890/7157/8900 6 Human_herpesvirus_6B R-HSA-5620912 Anchoring of the basal body to the plasma membrane 17/678 98/10654 1.3360852208951456e-4 6.359765651460893e-4 3.6816570531332906e-4 22995/5518/5347/3320/8766/7531/10142/22832/11190/4218/8655/10733/983/7532/4751/5577/5566 17 Human_herpesvirus_6B R-HSA-5674135 MAP2K and MAPK activation 10/678 40/10654 1.507211862525521e-4 7.142583649401916e-4 4.134829003388598e-4 409/8826/4140/71/3845/408/8844/7529/5594/5595 10 Human_herpesvirus_6B R-HSA-5627117 RHO GTPases Activate ROCKs 7/678 20/10654 1.528559366213314e-4 7.211837362178235e-4 4.1749198548557485e-4 388/387/4659/4627/4629/5500/389 7 Human_herpesvirus_6B R-HSA-2559585 Oncogene Induced Senescence 9/678 33/10654 1.5673223239364402e-4 7.298270473634467e-4 4.2249558297417084e-4 1019/4343/1021/7027/7157/5594/6233/5595/4193 9 Human_herpesvirus_6B R-HSA-68962 Activation of the pre-replicative complex 9/678 33/10654 1.5673223239364402e-4 7.298270473634467e-4 4.2249558297417084e-4 51053/1017/6119/6118/4173/8318/6117/990/55388 9 Human_herpesvirus_6B R-HSA-9022692 Regulation of MECP2 expression and activity 9/678 33/10654 1.5673223239364402e-4 7.298270473634467e-4 4.2249558297417084e-4 815/4343/808/801/816/817/9212/805/5566 9 Human_herpesvirus_6B R-HSA-9006931 Signaling by Nuclear Receptors 36/678 299/10654 1.5810701671942936e-4 7.330416229718998e-4 4.243564950911091e-4 2962/7514/1025/5170/2963/5437/5441/5434/5440/6464/1956/5438/4343/3320/808/5431/3845/2100/5435/5433/801/5439/1655/5430/2066/5432/861/23028/207/5436/2099/5594/208/4609/5595/805 36 Human_herpesvirus_6B R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 15/678 82/10654 1.7821878270169562e-4 8.191944904442748e-4 4.742302372319798e-4 22995/5518/5347/440145/3320/7531/10142/11190/8655/10733/983/7532/4751/5577/5566 15 Human_herpesvirus_6B R-HSA-380287 Centrosome maturation 15/678 82/10654 1.7821878270169562e-4 8.191944904442748e-4 4.742302372319798e-4 22995/5518/5347/440145/3320/7531/10142/11190/8655/10733/983/7532/4751/5577/5566 15 Human_herpesvirus_6B R-HSA-430039 mRNA decay by 5' to 3' exoribonuclease 6/678 15/10654 1.9784822032072622e-4 8.969432440223685e-4 5.192388527487102e-4 51690/23658/11157/57819/27258/25804 6 Human_herpesvirus_6B R-HSA-5358508 Mismatch Repair 6/678 15/10654 1.9784822032072622e-4 8.969432440223685e-4 5.192388527487102e-4 6119/6118/4436/6117/9156/5111 6 Human_herpesvirus_6B R-HSA-2465910 MASTL Facilitates Mitotic Progression 5/678 10/10654 1.9808847804212077e-4 8.969432440223685e-4 5.192388527487102e-4 5518/55844/84930/891/983 5 Human_herpesvirus_6B R-HSA-6807070 PTEN Regulation 21/678 140/10654 1.9848323887329723e-4 8.969432440223685e-4 5.192388527487102e-4 10014/10197/4343/8726/23512/1459/6615/2146/5978/7157/1107/1457/23028/207/4734/6045/5594/208/1108/6233/5595 21 Human_herpesvirus_6B R-HSA-187687 Signalling to ERKs 9/678 34/10654 2.0127024109039906e-4 9.057160849067958e-4 5.243174347733086e-4 5898/1432/6464/4914/3845/6300/7529/5594/5595 9 Human_herpesvirus_6B R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 20/678 132/10654 2.4369683165396323e-4 0.001092047308374036 6.321842494789005e-4 672/1017/6119/6118/545/472/151987/580/6117/11073/9156/84126/890/1111/8900/641/5111/8924/6233/7517 20 Human_herpesvirus_6B R-HSA-2559583 Cellular Senescence 26/678 195/10654 2.6128478366911016e-4 0.0011659833471234042 6.749856911452014e-4 898/1017/7014/1432/25913/472/9134/1019/5601/11065/4343/8726/8881/23512/1021/7027/890/2146/7157/5970/8900/6045/5594/6233/5595/4193 26 Human_herpesvirus_6B R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 14/678 76/10654 2.6927944681534284e-4 0.001195531176637926 6.920908772320394e-4 701/5347/10197/11065/8881/891/890/991/4085/8900/983/4751/9232/6233 14 Human_herpesvirus_6B R-HSA-8856688 Golgi-to-ER retrograde transport 20/678 133/10654 2.701386972421831e-4 0.001195531176637926 6.920908772320394e-4 22820/830/3832/11316/10112/10749/1062/6836/24137/56992/9493/8655/1315/23303/140735/832/54732/11004/829/3835 20 Human_herpesvirus_6B R-HSA-5620920 Cargo trafficking to the periciliary membrane 11/678 51/10654 2.922900590677859e-4 0.0012882413714469083 7.457606445350917e-4 55763/56623/54536/8766/60412/10640/4218/11336/149371/55770/23265 11 Human_herpesvirus_6B R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 6/678 16/10654 2.996123672815064e-4 0.0013036111066551644 7.546581569805807e-4 5934/1874/7027/890/983/5933 6 Human_herpesvirus_6B R-HSA-442982 Ras activation upon Ca2+ influx through NMDA receptor 7/678 22/10654 3.006460722164571e-4 0.0013036111066551644 7.546581569805807e-4 815/808/3845/801/816/817/805 7 Human_herpesvirus_6B R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 7/678 22/10654 3.006460722164571e-4 0.0013036111066551644 7.546581569805807e-4 351/994/8851/995/7531/993/1020 7 Human_herpesvirus_6B R-HSA-8863678 Neurodegenerative Diseases 7/678 22/10654 3.006460722164571e-4 0.0013036111066551644 7.546581569805807e-4 351/994/8851/995/7531/993/1020 7 Human_herpesvirus_6B R-HSA-69615 G1/S DNA Damage Checkpoints 13/678 68/10654 3.0250514916932013e-4 0.0013063831240336364 7.562628729233004e-4 898/1017/11200/472/9134/10197/993/890/1111/7157/8900/6233/4193 13 Human_herpesvirus_6B R-HSA-1257604 PIP3 activates AKT signaling 32/678 264/10654 3.202918475629055e-4 0.001377640838312738 7.975138373052265e-4 10014/5170/5518/1956/10197/4343/8726/23512/2100/2065/1459/6615/3630/2146/5978/7157/1107/2066/1457/23028/207/4734/6045/2099/5594/208/1108/5879/6233/5595/4193/79109 32 Human_herpesvirus_6B R-HSA-445717 Aquaporin-mediated transport 11/678 52/10654 3.4976964191338057e-4 0.0014984131459569222 8.67428711945184e-4 359/4645/5576/22841/5573/8766/5575/5567/5577/5568/5566 11 Human_herpesvirus_6B R-HSA-109581 Apoptosis 24/678 178/10654 3.7663409329422097e-4 0.0016070721670044248 9.303312264638127e-4 1613/7533/2810/1829/10197/598/7534/708/1499/7531/7027/8655/7157/7532/90427/207/10971/140735/7529/5594/208/6233/5595/6709 24 Human_herpesvirus_6B R-HSA-69306 DNA Replication 19/678 127/10654 4.0736446416746674e-4 0.0017299955277001536 0.0010014913418992487 51053/8454/898/1017/6119/6118/4173/9134/10197/11065/8318/6117/8881/990/890/8900/5111/6233/55388 19 Human_herpesvirus_6B R-HSA-73980 RNA Polymerase III Transcription Termination 7/678 23/10654 4.086730798395321e-4 0.0017299955277001536 0.0010014913418992487 4774/5437/5441/5434/5440/5435/9533 7 Human_herpesvirus_6B R-HSA-5693538 Homology Directed Repair 20/678 138/10654 4.4354104879911415e-4 0.0018702065482828789 0.0010826592529742157 672/1017/6119/6118/545/472/151987/580/6117/11073/9156/84126/890/1111/8900/641/5111/8924/6233/7517 20 Human_herpesvirus_6B R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 14/678 80/10654 4.667418055224504e-4 0.0019603155831942917 0.0011348232134271343 701/8454/1017/5347/10197/11065/8881/891/890/991/4085/8900/983/6233 14 Human_herpesvirus_6B R-HSA-5357801 Programmed Cell Death 24/678 181/10654 4.8292285060071464e-4 0.0020203530195053335 0.0011695787787986058 1613/7533/2810/1829/10197/598/7534/708/1499/7531/7027/8655/7157/7532/90427/207/10971/140735/7529/5594/208/6233/5595/6709 24 Human_herpesvirus_6B R-HSA-2980736 Peptide hormone metabolism 15/678 90/10654 5.0991158947992e-4 0.0021249623047976435 0.001230136908472959 4644/55763/25924/54536/1499/60412/5873/10640/3630/11336/149371/6934/55770/23265/6844 15 Human_herpesvirus_6B R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 12/678 63/10654 5.300557279530077e-4 0.002200347614874695 0.0012737773307397863 5437/5441/5434/5440/8517/5435/1499/2547/1660/5970/9533/6233 12 Human_herpesvirus_6B R-HSA-399719 Trafficking of AMPA receptors 8/678 31/10654 5.48881754534772e-4 0.002260970611949003 0.0013088718761983028 815/160/2890/2891/816/817/4646/4193 8 Human_herpesvirus_6B R-HSA-399721 Glutamate binding, activation of AMPA receptors and synaptic plasticity 8/678 31/10654 5.48881754534772e-4 0.002260970611949003 0.0013088718761983028 815/160/2890/2891/816/817/4646/4193 8 Human_herpesvirus_6B R-HSA-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation 5/678 12/10654 5.59245275867321e-4 0.002286075154404201 0.00132340485128908 3320/808/801/207/805 5 Human_herpesvirus_6B R-HSA-3371511 HSF1 activation 5/678 12/10654 5.59245275867321e-4 0.002286075154404201 0.00132340485128908 6119/6118/3320/6117/7531 5 Human_herpesvirus_6B R-HSA-166520 Signaling by NTRKs 16/678 101/10654 6.02109732033585e-4 0.002451937349840188 0.0014194221819803145 5898/1432/5518/387/6464/8851/4914/160/3845/6300/1020/7529/5594/5879/5595/7074 16 Human_herpesvirus_6B R-HSA-73780 RNA Polymerase III Chain Elongation 6/678 18/10654 6.223210720223345e-4 0.0025246434399087887 0.001461511608537301 5437/5441/5434/5440/5435/9533 6 Human_herpesvirus_6B R-HSA-9006936 Signaling by TGF-beta family members 16/678 102/10654 6.730298445463125e-4 0.002720056466072078 0.0015746358627121274 22938/7514/57154/1025/8812/387/57530/1874/7027/5501/5499/4738/5933/5500/4609/6233 16 Human_herpesvirus_6B R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 8/678 32/10654 6.916012852749578e-4 0.002784605174922856 0.001612002995753661 22938/1025/8812/1874/7027/5933/4609/6233 8 Human_herpesvirus_6B R-HSA-8873719 RAB geranylgeranylation 12/678 65/10654 7.119497284155597e-4 0.0028557983488129756 0.0016532165978189026 5864/9230/10890/5874/5872/8766/5873/4218/51762/51552/57111/5865 12 Human_herpesvirus_6B R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 7/678 25/10654 7.166502851483464e-4 0.00286392707236522 0.0016579223014625926 701/11065/8881/991/4085/4751/6233 7 Human_herpesvirus_6B R-HSA-5684996 MAPK1/MAPK3 signaling 30/678 255/10654 8.023510773443649e-4 0.0031944907205792373 0.0018492850109795773 409/8826/815/9462/5518/6464/1956/10197/6711/4140/808/8452/71/3845/408/2065/801/4763/816/8844/2066/983/817/5245/7529/5594/6233/5595/805/6709 30 Human_herpesvirus_6B R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 13/678 75/10654 8.096488272171322e-4 0.0032116070146279577 0.0018591936032393407 701/10197/11065/8881/891/890/991/4085/8900/983/4751/9232/6233 13 Human_herpesvirus_6B R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 15/678 94/10654 8.170826752645139e-4 0.003229134853167138 0.0018693404378745339 22995/5518/5347/440145/3320/7531/10142/11190/8655/10733/983/7532/4751/5577/5566 15 Human_herpesvirus_6B R-HSA-9607240 FLT3 Signaling 31/678 267/10654 8.251032607048942e-4 0.0032488440890255208 0.0018807500795479206 409/5170/8826/815/9462/5518/6464/1956/10197/6711/4140/808/8452/71/3845/408/2065/801/4763/816/8844/2066/817/5245/7529/5594/208/6233/5595/805/6709 31 Human_herpesvirus_6B R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 6/678 19/10654 8.610435714839367e-4 0.0033427485450959276 0.0019351112025765408 6464/1956/3320/3845/11140/6233 6 Human_herpesvirus_6B R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 6/678 19/10654 8.610435714839367e-4 0.0033427485450959276 0.0019351112025765408 6464/1956/3320/3845/11140/6233 6 Human_herpesvirus_6B R-HSA-203615 eNOS activation 5/678 13/10654 8.614365998566535e-4 0.0033427485450959276 0.0019351112025765408 3320/808/801/207/805 5 Human_herpesvirus_6B R-HSA-879415 Advanced glycosylation endproduct receptor signaling 5/678 13/10654 8.614365998566535e-4 0.0033427485450959276 0.0019351112025765408 830/351/5594/829/5595 5 Human_herpesvirus_6B R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 16/678 106/10654 0.0010324673185799257 0.00399195847725307 0.002310937680576007 409/1080/29978/1956/160/917/9146/408/10987/4738/1212/30011/6233/1601/51138/6844 16 Human_herpesvirus_6B R-HSA-5673001 RAF/MAP kinase cascade 29/678 249/10654 0.0011428108530794497 0.004402699365640614 0.0025487148521915787 409/8826/815/9462/5518/6464/1956/10197/6711/4140/808/8452/71/3845/408/2065/801/4763/816/8844/2066/817/5245/7529/5594/6233/5595/805/6709 29 Human_herpesvirus_6B R-HSA-1852241 Organelle biogenesis and maintenance 33/678 296/10654 0.0011491204051651985 0.0044111396198276975 0.002553600900367108 55763/1432/22995/55112/5518/5347/3320/808/56623/54536/8766/7531/10142/22832/60412/6300/801/10640/11190/4218/8655/10733/11336/983/7532/140735/4751/149371/5577/805/55770/23265/5566 33 Human_herpesvirus_6B R-HSA-167044 Signalling to RAS 6/678 20/10654 0.0011645525578536217 0.004454413533790103 0.0025786520923901626 5898/1432/6464/4914/3845/6300 6 Human_herpesvirus_6B R-HSA-76066 RNA Polymerase III Transcription Initiation From Type 2 Promoter 7/678 27/10654 0.001184310621046087 0.0045138671713180045 0.0026130696976817583 5437/5441/5434/5440/2975/5435/9533 7 Human_herpesvirus_8_type_P R-HSA-5663202 Diseases of signal transduction 343/5323 377/10654 7.92054709347873e-68 1.1144209760524572e-64 4.110347070615804e-65 5295/8454/2308/27123/5689/374/4893/11052/2250/5335/71/79718/5682/5291/892/5526/817/1452/9530/613/9372/182/5908/3082/941/55109/143471/23385/2064/5705/54845/5431/6776/5435/5709/9978/5433/5695/8546/9759/9612/22866/5605/4609/4089/22938/5037/5711/1387/3717/10827/4088/2244/6907/5683/145957/324/2534/3690/408/9965/5699/6400/8312/11064/5439/2264/5702/4296/5894/6868/9794/9542/2885/2475/8660/51009/8826/9846/5518/57534/2252/6469/1185/4140/7040/3845/388585/3265/80351/4763/5696/7750/5691/28514/7314/5879/5515/5718/818/8805/1839/26127/5290/3667/8823/79885/2065/2648/9734/55869/55750/5700/3815/122706/5707/10956/8844/51564/7094/8322/55534/5594/3280/2069/84335/8074/7249/23198/84441/7414/10533/10013/23164/2260/5438/5528/83933/3714/89780/102/8323/57085/2249/6714/2099/5664/9861/2248/5519/9061/8850/399687/2932/7046/2247/5698/5880/10000/5692/5713/2335/1445/5710/3066/2280/5719/6233/2266/7409/2246/4040/2251/3932/2931/2243/7855/118788/6777/369/801/5781/5663/940/1523/57670/253260/805/5170/2963/5434/7276/6464/142678/572/283455/3674/5436/4303/4041/409/930/5706/6199/10046/9208/84447/673/8315/6774/2263/4233/8658/1024/5714/6772/6934/64223/10014/2962/8503/5688/5159/5687/5708/3084/26508/9148/5529/816/4087/208/6654/5704/83464/10718/79109/56829/7048/23493/7311/5293/7450/1956/11160/60/9444/55851/2549/51107/5694/4851/5432/22916/11140/7529/5595/5516/4000/1147/27044/815/5440/5684/22906/8841/685/5720/8087/1487/2309/5604/1499/10018/5525/10142/842/139285/5430/23462/207/5690/5717/1027/9491/6500/8817/5441/10197/54518/2100/2254/4686/7316/10213/152831/1950/9611/54492/1026/55615/50852/26281/10818/7415/5715/80853/10256/2261/5701/867/5437/5685/2255/3164/3320/5686/2033/54894/391/55294/5728/3065/2066/27006/942/5527/1488/5716/1385/5906/5155/54567/4254/5296/808/3516/9715/5693/5721/5245/5156/4193 343 Human_herpesvirus_8_type_P R-HSA-3700989 Transcriptional Regulation by TP53 327/5323 365/10654 1.268345005106593e-60 8.922807110924882e-58 3.291021513250266e-58 6884/6875/834/5563/3725/9134/4436/83990/64769/5892/9156/57060/1763/7531/1459/79370/7486/6874/10971/9997/133383/9212/5982/27327/7295/7533/2810/55367/1460/11200/472/53632/79813/5431/7001/639/5435/5433/1869/28996/84289/1457/6790/25904/29117/4194/4514/1647/5928/1432/1387/4683/10325/56950/51499/2965/84126/5439/192669/1107/8900/6873/5371/2475/672/55571/6881/2967/51616/5518/1386/55835/10670/4513/4343/6117/11198/7159/57472/904/144455/85456/29883/51497/51230/637/64121/83695/7296/7314/5515/1263/27166/23368/23774/6118/2176/3622/7027/6446/2936/7832/51422/7249/404672/898/117584/27244/7534/332/5438/5934/64065/116028/890/10769/983/1643/8797/9656/5519/27154/5458/83860/57459/2821/2177/10000/5985/2877/900/7994/2068/54541/3066/7157/5984/6233/1025/2353/604/63970/839/10419/5325/50484/5600/6883/7936/6829/79733/26523/7874/317/2744/5608/5884/5810/57521/26155/26013/5875/253260/28956/25920/5170/80010/2963/5434/83667/1820/7862/1029/389541/5457/9219/8445/7532/5436/55240/204851/6878/4869/5931/58528/4850/4292/580/11073/891/80196/54971/4331/5366/641/51241/5111/1108/8148/2966/246175/64223/2962/84883/6119/147923/3364/5571/10524/54457/4848/8812/144715/23019/1616/843/6794/54815/94241/1874/10128/6009/905/1111/2071/55215/8626/208/79109/55004/7311/7161/5562/6880/6908/5983/5564/6882/5565/1020/53615/10397/8795/5432/665/7248/6877/7529/5516/1017/27161/27113/9891/6917/5440/27165/5305/8621/902/5883/25946/9540/5430/10111/8793/207/22974/57690/835/4849/1027/58484/3486/355/6749/545/5441/8794/192670/153129/8550/7469/9337/7316/6872/2539/1026/54205/55615/5933/124446/5395/6879/9150/112858/5876/143686/10848/5437/9099/8649/28984/51755/2033/995/5728/3065/91875/6827/23112/10498/10542/5527/2968/5932/8851/5300/7156/581/3276/5052/138474/133746/1022/8178/10919/4193 327 Human_herpesvirus_8_type_P R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 234/5323 244/10654 4.8220352820817226e-58 2.261534547296328e-55 8.341275066899262e-56 8449/23165/6633/8683/6431/84271/55696/4904/51639/51585/9128/199746/23450/348995/57122/5431/9092/23511/81608/5435/6625/5433/51645/3190/1477/9416/65109/56339/22826/23279/8233/22938/988/23020/23225/6631/3181/5439/1660/9410/6638/57721/9877/9972/8021/3312/10907/10291/55746/26121/10262/7919/53981/6432/10084/8563/6430/51340/56001/6627/6936/83443/11051/80145/9129/9879/10081/8106/51690/27238/55749/5438/85313/10762/54883/22794/9785/11338/1655/9343/29107/3185/4116/6626/11157/285755/1478/24144/79902/9883/51213/10236/10250/4670/26097/51362/10465/55660/25949/23283/2521/1977/3191/10285/6636/23524/10914/57187/6396/129401/79228/8175/2733/84950/3188/84324/56259/5725/1994/10450/7536/4928/2963/6635/5434/5903/220988/6632/10283/55706/7175/24148/154007/7884/23350/5436/10523/6428/27258/10212/6637/55110/5093/55954/84321/6429/57819/4927/10181/2962/10898/10569/23658/6434/9295/84844/10482/51692/10421/11193/8086/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/55599/51691/10946/9631/27339/5430/79869/85437/11325/57703/3184/25804/29894/9589/11017/51503/3178/79023/5441/23636/3183/79622/10594/4686/8189/23398/10713/53371/10978/5546/7307/10772/9688/9984/5437/6629/10189/10949/51729/11066/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/84248/6427/5356/84991/8480/10992/55339/6628 234 Human_herpesvirus_8_type_P R-HSA-9006925 Intracellular signaling by second messengers 278/5323 305/10654 2.2483156659080076e-55 6.490879173946778e-53 2.394047381704831e-53 5295/1912/2308/5689/374/3725/6591/3643/2250/5335/5682/5291/1822/1459/5526/9112/817/6045/5578/5582/27327/80012/3082/1460/941/143471/2064/5705/5709/5695/107/1457/1911/4734/11060/5711/5928/10325/5683/145957/2534/23512/9965/57332/5699/2444/2264/3630/5702/192669/1107/8975/3654/5371/9542/2885/2475/51135/8660/5518/1386/10670/2252/4343/80351/64121/5696/814/5691/7314/5879/5515/5718/818/23396/1839/5290/3667/8823/90865/2065/23186/5700/3815/122706/5707/5567/2146/51564/5594/2069/84335/84232/8074/7249/23198/112/57761/2260/5573/5528/111/2249/6714/2099/9861/7101/81847/2248/5519/2932/84733/57459/2247/5698/5880/10000/5692/5713/5710/3066/7157/5613/5719/6233/5580/7409/2246/2251/3932/2931/118788/331/8726/196883/115/26523/7874/801/5781/57521/23608/940/6015/253260/28956/805/5170/3838/572/23239/389541/9219/8535/4303/5568/930/5931/58528/5706/6199/113/2263/4233/8658/5714/10645/1108/2122/64223/5566/84254/10014/8503/5688/5159/5687/5708/3084/54815/6009/5529/816/7189/208/5577/5704/10718/79109/55004/57504/7311/5293/1956/648/2549/5694/23466/53615/109/5595/3556/5516/1147/27161/815/5684/8841/685/5305/5720/2309/5468/5525/5575/842/5978/8870/10273/207/5690/57690/5717/1027/9491/8817/114/10197/108/192670/4615/153129/2100/2254/7316/10213/152831/1950/1026/55615/50852/10768/26281/57167/10818/5715/1958/2261/5701/5576/5685/2255/8649/3164/5686/391/5728/6615/3065/2066/27006/23028/942/5987/23112/10542/5527/5716/1385/5155/4254/5296/5581/808/5693/5721/5156/4193 278 Human_herpesvirus_8_type_P R-HSA-5663205 Infectious disease 334/5323 383/10654 2.3066379438332546e-55 6.490879173946778e-53 2.394047381704831e-53 3839/6804/6158/6884/23165/6875/5689/6138/2237/6227/7852/6206/6234/6191/162/6128/5682/6132/6129/4057/6874/6176/1174/811/6224/6146/348995/6154/143471/6202/57122/5705/3981/6169/5431/23511/5435/5709/9978/6175/5433/6218/5695/2960/292/567/6173/23279/5605/6167/5711/23327/116832/112755/29082/8732/23225/5683/2965/2534/6156/27183/5699/6143/5439/5702/6456/6873/3836/6139/30011/2885/163/9972/6881/2967/51616/3921/8021/7040/11198/904/51497/5062/55746/6208/5696/6170/5691/7296/7314/5879/5718/3303/8945/6203/1839/161/402569/5606/6147/25978/5700/51160/122706/5707/2959/6222/2060/7518/8106/23198/404672/9636/10015/5438/6134/3978/10762/79720/6155/1500/51534/4836/926/9397/6714/6231/9861/79902/6142/11168/9883/118429/23521/83860/51510/999/5698/9146/6455/5692/5713/5710/2068/6207/5478/5719/6233/6844/7514/1025/3932/1213/5610/1211/6188/6396/129401/6883/7936/1175/6829/801/5608/200916/6122/2957/940/805/25920/6230/60489/1173/4928/2963/3838/5434/5903/6857/6194/55706/7175/6166/1938/5436/6136/6878/6125/4869/821/5706/6232/160/6160/6616/293/5611/920/4233/4331/5714/6193/4927/6210/6229/8148/6205/2966/2962/10898/3840/5688/54457/8812/5687/5708/128866/140801/6235/905/6181/2071/5901/8086/5704/3326/7311/6223/25873/6880/6908/7251/5694/3304/1104/2547/9045/6882/2961/6187/6416/5432/6168/22916/1234/6157/6137/6877/5905/6144/3837/6917/5440/164/5684/9349/8065/4736/2926/5720/902/51121/9631/5604/1499/3159/6159/6217/5430/6152/5690/7520/5717/9491/6500/6749/51065/6141/79023/6123/5441/23636/10197/7469/919/6164/4686/7316/10213/6872/53371/3055/6209/9688/11224/6165/6130/6879/9150/5715/6204/5701/2958/867/6228/5437/5685/3320/8815/5686/6124/6827/5609/2968/5716/6843/9844/2984/6189/808/6135/6201/375/6161/138474/1022/5693/10254/5721/8178/8480/6133/291 334 Human_herpesvirus_8_type_P R-HSA-1257604 PIP3 activates AKT signaling 244/5323 264/10654 1.4807223935308436e-51 3.472294012829828e-49 1.280694982474923e-49 5295/1912/2308/5689/374/3725/6591/3643/2250/5682/5291/1822/1459/5526/9112/6045/27327/80012/3082/1460/941/143471/2064/5705/5709/5695/1457/1911/4734/11060/5711/5928/10325/5683/145957/2534/23512/9965/57332/5699/2444/2264/3630/5702/192669/1107/8975/3654/5371/9542/2885/2475/51135/8660/5518/1386/10670/2252/4343/80351/64121/5696/5691/7314/5879/5515/5718/23396/1839/5290/3667/8823/90865/2065/23186/5700/3815/122706/5707/2146/51564/5594/2069/84335/84232/8074/7249/23198/57761/2260/5528/2249/6714/2099/9861/7101/81847/2248/5519/2932/84733/57459/2247/5698/5880/10000/5692/5713/5710/3066/7157/5719/6233/7409/2246/2251/3932/2931/118788/331/8726/26523/7874/5781/57521/23608/940/6015/253260/28956/5170/572/23239/389541/9219/8535/4303/930/5931/58528/5706/6199/2263/4233/8658/5714/1108/2122/64223/10014/8503/5688/5159/5687/5708/3084/54815/6009/5529/7189/208/5704/10718/79109/55004/57504/7311/5293/1956/648/2549/5694/23466/53615/5595/3556/5516/1147/27161/5684/8841/685/5305/5720/2309/5468/5525/842/5978/8870/10273/207/5690/57690/5717/1027/9491/8817/10197/192670/4615/153129/2100/2254/7316/10213/152831/1950/1026/55615/50852/26281/57167/10818/5715/1958/2261/5701/5685/2255/8649/3164/5686/391/5728/6615/3065/2066/27006/23028/942/5987/23112/10542/5527/5716/1385/5155/4254/5296/5693/5721/5156/4193 244 Human_herpesvirus_8_type_P R-HSA-449147 Signaling by Interleukins 382/5323 461/10654 4.640541295111212e-51 9.327488003173536e-49 3.440280990210267e-49 5295/729230/8454/6804/3605/7124/2308/834/1052/5689/3725/7291/5777/9252/1437/4790/5682/5291/1511/26469/5657/5783/27178/1848/356/3593/246/9021/8878/6624/5908/3082/5743/3091/941/1265/143471/10538/3383/5705/11009/6097/6657/3576/3313/3662/6776/3688/4985/5709/9978/6175/2920/5695/1435/4792/59307/7133/3606/177/4609/3603/5898/5711/4988/1432/3558/3717/4088/836/5683/2534/84867/2162/5699/3181/5702/4001/3654/3563/2885/51135/8660/6196/3594/1154/9846/6347/5518/1386/6382/7040/3588/6197/4282/7334/3600/3312/1399/3551/3965/3569/5062/5696/5691/51231/4692/7314/3572/3596/5515/257397/5718/54014/10148/8945/1326/5601/1072/3635/5290/3667/6627/6283/5606/90865/9049/11213/7412/5700/122706/5707/27250/8767/3911/1849/29110/1439/5594/4582/23198/28512/23118/4312/9987/8517/6778/7534/6810/332/5528/4313/3565/3934/3976/3185/5970/5443/9261/3718/3627/8807/8809/9861/149233/5519/5598/4208/3567/598/2247/5698/5692/5713/2335/595/6195/5710/3458/10454/7157/5478/1271/5719/6233/7525/6844/7409/2353/604/6809/3932/7076/302/552900/51561/3570/8835/5600/6777/6773/7297/5781/5608/4791/1846/59067/3557/3562/351/6464/3566/6597/5782/6351/7184/3589/6775/50616/3684/9446/54472/821/4318/5706/3726/58480/301/4478/1438/6616/79155/6774/920/6850/5780/1440/5714/6772/8651/5566/64127/8503/1901/3552/2889/5688/79923/5687/4067/29760/3636/5708/5602/3656/57162/5771/998/6648/7189/6654/5704/3716/7311/2939/1270/6888/5293/2185/240/6655/6356/5008/5694/23765/6416/1234/3586/3554/829/28511/5595/3556/5516/1147/5778/1845/596/5055/5684/2208/5720/6885/2309/5604/4215/3561/3578/10392/207/5292/5451/7422/5690/3553/2625/1230/5717/2919/9491/6500/3568/25930/246330/10197/4615/2357/1436/26525/7316/10213/3560/6352/4314/7335/1441/4205/3055/1026/6348/4793/5775/3146/6647/6364/5715/7132/5701/867/466/6950/23291/5685/3320/5686/4843/6288/2002/942/6285/5609/1398/58985/948/5716/1385/53832/6363/3575/6845/5896/5296/6935/3687/5599/5784/7431/375/3559/3574/3929/3162/1489/57161/1278/4170/5693/3689/5721/3601/5724/5034 382 Human_herpesvirus_8_type_P R-HSA-72172 mRNA Splicing 185/5323 191/10654 3.8983066703630115e-48 6.8561468565009465e-46 2.528769984853901e-46 8449/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/5431/9092/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/8233/22938/988/23020/6631/3181/5439/1660/9410/6638/3312/10907/10291/26121/10262/53981/6432/10084/6430/51340/6627/6936/83443/11051/9129/9879/10081/8106/51690/27238/55749/5438/85313/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/10236/10250/4670/51362/10465/55660/25949/23283/2521/3191/10285/6636/23524/10914/8175/84950/3188/56259/5725/1994/10450/7536/2963/6635/5434/220988/6632/10283/24148/154007/23350/5436/10523/6428/27258/6637/55110/5093/55954/6429/57819/10181/2962/10898/10569/23658/6434/9295/84844/51692/10421/11193/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/55599/51691/10946/27339/5430/79869/85437/11325/57703/3184/25804/29894/11017/51503/3178/5441/3183/79622/10594/4686/8189/23398/10713/10978/5546/7307/10772/5437/6629/10189/10949/51729/11066/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/84991/10992/55339/6628 185 Human_herpesvirus_8_type_P R-HSA-913531 Interferon Signaling 190/5323 199/10654 2.684320147417425e-46 4.1964871637959076e-44 1.5478009738909833e-44 80263/3839/3443/23165/201626/5777/5335/960/5770/3107/817/9021/348995/317649/3383/57122/11274/55223/3662/3115/23511/4684/567/4734/6672/3113/23279/3106/8672/3459/3717/23225/3117/1973/11074/3836/5371/4599/684/9972/3133/3429/117854/8021/3127/91543/7334/4938/4261/55746/5696/7314/3445/818/402569/115362/7412/10410/85363/9830/163351/9636/3126/2634/3444/10762/2317/115361/103/3434/10475/3433/79902/23586/9883/3451/10437/3448/1981/10612/3458/3661/7324/1977/3439/51191/6233/5580/81603/10107/5610/10581/3452/4940/6396/3437/129401/6773/7297/5781/3430/3660/3446/8554/3135/3665/3120/4928/3838/5903/10379/55706/7175/3455/2316/2633/4600/3123/23650/2209/8638/25820/1982/7706/23087/9470/3122/3394/3663/6772/8651/4927/3659/3840/25939/2635/3440/5771/3454/816/8086/10346/9246/3716/7311/3125/7726/79097/3456/53840/3105/1974/5595/3460/815/3837/3441/6737/51447/9631/23321/4281/3119/4502/54739/79023/2537/23636/3449/51127/7316/53371/8519/3664/9688/6041/1958/4939/388646/7341/6059/55128/3669/3134/5300/9775/80128/5495/5724/8480 190 Human_herpesvirus_8_type_P R-HSA-72163 mRNA Splicing - Major Pathway 177/5323 183/10654 8.868570211588712e-46 1.2478078287705318e-43 4.602321172961302e-44 8449/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/5431/9092/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/22938/988/23020/6631/3181/5439/1660/9410/6638/3312/10907/10291/26121/10262/53981/6432/10084/6430/51340/6627/6936/83443/11051/9129/9879/8106/51690/27238/55749/5438/85313/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/10236/10250/4670/51362/10465/55660/25949/23283/2521/3191/10285/6636/23524/10914/8175/84950/3188/56259/5725/1994/10450/7536/2963/6635/5434/220988/6632/10283/24148/23350/5436/10523/6428/27258/6637/55110/5093/6429/57819/10181/2962/10898/10569/23658/6434/9295/84844/51692/10421/11193/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/51691/10946/27339/5430/79869/11325/57703/3184/25804/29894/11017/51503/3178/5441/3183/10594/4686/8189/23398/10713/10978/5546/7307/10772/5437/6629/10189/10949/51729/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/84991/10992/55339/6628 177 Human_herpesvirus_8_type_P R-HSA-453274 Mitotic G2-G2/M phases 188/5323 198/10654 1.0284524370091309e-44 1.3154841626107702e-42 4.851933506655518e-43 114791/10844/8454/5689/440145/5682/7531/11190/203068/54801/51807/63943/79441/143471/10381/5705/5116/5048/5709/9978/1869/5695/8655/6790/9702/5711/5928/7846/7840/113457/5683/5699/11064/5702/5520/81027/8900/28227/5518/55835/29922/23332/7465/93323/5696/5691/7314/5515/5718/8945/79861/4659/5700/122706/5707/1454/23198/993/890/983/9861/79959/5519/5698/5692/5713/80097/10376/5710/10540/7157/85378/5719/6233/7514/54930/54820/1453/27229/9793/4218/5500/84617/2305/11258/22981/8636/51512/7532/84962/55125/10382/121441/7277/5706/9133/286826/9814/653784/23354/728642/891/9738/4331/1639/5714/55722/4957/5566/5688/5687/91750/7283/347733/5708/22919/984/10426/22994/79866/1069/5577/5704/3326/55957/7311/10133/10383/5347/84790/80184/5694/22897/5108/7280/10806/1778/5516/115106/1017/22822/22995/55559/5684/994/5720/4605/902/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/1781/7316/10213/80321/1026/10121/1871/5715/84131/9088/5701/23291/5685/3320/5686/2033/995/10733/4751/27175/80254/5716/9662/55142/1022/8481/5693/5721/132660/55755 188 Human_herpesvirus_8_type_P R-HSA-69275 G2/M Transition 186/5323 196/10654 3.8444079001269735e-44 4.5075682628988765e-42 1.6625378024233317e-42 114791/10844/8454/5689/440145/5682/7531/11190/203068/54801/51807/63943/79441/143471/10381/5705/5116/5048/5709/9978/5695/8655/6790/9702/5711/5928/7846/7840/113457/5683/5699/11064/5702/5520/81027/8900/28227/5518/55835/29922/23332/7465/93323/5696/5691/7314/5515/5718/8945/79861/4659/5700/122706/5707/1454/23198/993/890/983/9861/79959/5519/5698/5692/5713/80097/10376/5710/10540/7157/85378/5719/6233/7514/54930/54820/1453/27229/9793/4218/5500/84617/2305/11258/22981/8636/51512/7532/84962/55125/10382/121441/7277/5706/9133/286826/9814/653784/23354/728642/891/9738/4331/1639/5714/55722/4957/5566/5688/5687/91750/7283/347733/5708/22919/984/10426/22994/79866/1069/5577/5704/3326/55957/7311/10133/10383/5347/84790/80184/5694/22897/5108/7280/10806/1778/5516/115106/1017/22822/22995/55559/5684/994/5720/4605/902/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/1781/7316/10213/80321/1026/10121/5715/84131/9088/5701/23291/5685/3320/5686/2033/995/10733/4751/27175/80254/5716/9662/55142/1022/8481/5693/5721/132660/55755 186 Human_herpesvirus_8_type_P R-HSA-69242 S Phase 158/5323 161/10654 6.778551673441547e-44 7.336478618870967e-42 2.7059319635681645e-42 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/10274/5925/143471/5705/5709/5422/9978/1869/4174/5753/5695/84515/4609/4998/5711/5928/5683/990/5699/5702/8900/51529/29945/51434/84296/157570/6117/29882/5001/10714/7465/5558/5696/5691/7314/996/5718/6118/23594/7027/5700/122706/5707/64785/23198/898/3978/91768/5934/5557/993/890/51433/9861/2932/6502/5698/10000/5692/5985/5713/119504/595/4175/5710/5984/7324/5719/64682/6233/113130/23649/1163/5424/4999/4172/1019/5000/8318/246184/54107/4173/5706/286826/23047/8881/5885/4331/5425/5714/5111/6119/5688/5687/91750/5427/5708/1874/8243/81620/10393/208/5704/55957/51343/23595/7311/25906/51659/5983/5694/4176/56655/1017/5684/994/5720/902/57804/207/9837/5690/5717/1027/9491/6500/23244/10735/10197/4149/7316/10213/1875/1026/5426/4171/5715/5701/5685/5686/9126/5716/114799/5981/1022/5693/5721/132660 158 Human_herpesvirus_8_type_P R-HSA-5683057 MAPK family signaling cascades 256/5323 294/10654 3.111306061123144e-42 3.1268625914287597e-40 1.1532886376945187e-40 2308/5689/374/2118/3725/2674/4893/6711/2250/1437/71/5682/1844/1850/1848/5526/817/84292/27327/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/22866/5605/4609/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/192669/4296/5894/1847/3563/9542/2885/6709/8660/8997/8826/5518/2252/4140/4343/3845/5623/3265/4763/3569/5062/5696/5691/7314/3572/5879/5515/5923/5718/818/57554/1839/3667/8823/2065/5700/3815/122706/5707/5567/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/3337/4902/2260/5528/983/3718/2249/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/80824/1445/5710/8555/896/5719/6233/2266/2246/7514/2251/2243/1843/3570/26523/369/801/200734/7297/5781/8682/1846/11221/28956/805/9462/3562/6464/6712/2904/5747/283455/3674/7010/5568/2322/2675/3315/409/5706/1438/673/2676/8315/2263/4233/5597/84078/5714/5566/5688/5159/5687/5708/3084/5063/5529/816/998/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/5058/7529/5595/25759/5516/27161/815/5684/685/5720/2309/5604/3561/5525/153090/10642/10048/5690/57690/5717/9491/3568/8817/10817/10197/192670/5596/8550/54518/2254/7316/10213/152831/1950/3560/57731/26281/10818/5715/8437/10256/2261/5701/5685/2255/8649/53358/5686/2066/27006/8556/5979/23112/1742/5527/5716/88/5906/5155/9048/4254/5896/808/3559/8202/5693/5721/5245/5156/284 256 Human_herpesvirus_8_type_P R-HSA-2555396 Mitotic Metaphase and Anaphase 189/5323 202/10654 3.36951660603257e-42 3.1606065764585506e-40 1.1657345170344262e-40 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/113457/5683/1060/5699/5702/5520/81027/51529/4001/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/7444/5698/5692/5713/91687/119504/11243/10376/5710/7324/2010/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/26271/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/347733/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/5905/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/79023/55920/10735/10197/7443/23141/1781/7316/10213/4085/55166/5715/5701/5685/8815/5686/79003/9126/9232/23592/5527/9700/5716/701/57551/5693/5721 189 Human_herpesvirus_8_type_P R-HSA-453279 Mitotic G1-G1/S phases 147/5323 149/10654 5.1898533088326764e-42 4.5638272534547346e-40 1.6832879481937565e-40 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/1031/4998/5711/5928/10926/3717/5683/990/5699/5702/5520/8900/55388/1032/28227/1030/5518/6117/5001/7465/5558/5696/5691/7314/5515/6241/5718/6118/25/23594/7027/5700/5707/7153/898/91768/5934/5557/993/890/1876/983/6714/9861/5519/6502/5698/10000/5692/5713/595/4175/5710/896/5719/6233/7298/23649/1719/1163/1859/4999/4172/26271/1019/5000/8318/1029/54107/4173/5706/286826/891/4331/5714/5111/51053/6119/5688/5687/91750/5427/4067/5708/1874/81620/208/1870/5704/29935/55957/23595/7311/5694/4176/5516/56655/1017/894/5684/5720/4605/902/8317/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5933/5426/4171/1871/5715/5701/5685/5686/1021/3065/5716/1022/5693/5721/7083/132660/1028 147 Human_herpesvirus_8_type_P R-HSA-68882 Mitotic Anaphase 188/5323 201/10654 6.420146741325905e-42 5.313615567673852e-40 1.9598342684047506e-40 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/113457/5683/1060/5699/5702/5520/81027/51529/4001/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/7444/5698/5692/5713/91687/119504/11243/10376/5710/7324/2010/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/347733/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/5905/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/79023/55920/10735/10197/7443/23141/1781/7316/10213/4085/55166/5715/5701/5685/8815/5686/79003/9126/9232/23592/5527/9700/5716/701/57551/5693/5721 188 Human_herpesvirus_8_type_P R-HSA-68877 Mitotic Prometaphase 187/5323 200/10654 1.222735342519008e-41 9.55771459402358e-40 3.525196045975854e-40 114791/10844/55839/11130/440145/6249/9735/7531/1459/11190/203068/5526/54801/51807/9212/10274/1460/147841/348995/79441/10381/57122/5116/1780/23122/5048/57405/8655/1457/23279/9702/2491/7846/7840/113457/1060/11064/81027/11004/9184/5518/55835/29922/23332/25909/10726/81930/55746/93323/5515/79682/10403/79861/64151/25936/55869/1454/3619/64105/332/10051/5528/983/79902/3796/79959/5519/81565/80097/91687/11243/10376/23397/10540/85378/83540/7514/54930/54820/113130/6396/1453/27229/64946/9793/140735/220134/84617/4928/5903/11258/22981/55055/8636/80776/1783/401541/7532/55125/10382/79172/121441/7277/9133/79980/6232/23047/9814/653784/5885/23354/891/5501/9738/1639/55722/4957/5566/54821/9183/1062/699/7283/347733/22919/8243/10426/5529/22994/51143/1069/5577/10383/5347/84790/84643/80184/22897/5108/10592/7280/10806/1778/5516/115106/4926/5905/22995/55559/54908/55143/5525/10142/1058/991/79019/348235/80152/1063/8379/95681/23244/23421/79023/55920/10735/1781/80321/4085/55166/10121/84131/3320/79003/9126/9918/10733/4751/5527/27175/80254/701/57551/9662/55142/8481/55755 187 Human_herpesvirus_8_type_P R-HSA-5633007 Regulation of TP53 Activity 155/5323 160/10654 1.781958875411281e-40 1.3195874408966697e-38 4.8670677317327516e-39 6884/6875/5563/83990/64769/9156/1763/1459/7486/6874/133383/9212/5982/1460/11200/472/53632/79813/639/28996/84289/1457/6790/29117/4194/5928/1432/4683/56950/84126/1107/8900/6873/5371/2475/672/6881/51616/5518/6117/11198/7159/51230/83695/7314/5515/1263/23368/23774/6118/3622/6446/51422/117584/116028/890/983/5519/27154/5458/83860/57459/10000/5985/900/7994/3066/7157/5984/6233/10419/5600/6883/7874/5608/5884/5810/26155/26013/253260/5170/80010/7862/1029/5457/9219/8445/204851/6878/5931/580/11073/80196/54971/641/1108/8148/64223/6119/3364/5571/10524/54457/144715/1616/6794/54815/94241/1111/8626/208/79109/7311/7161/5562/6880/6908/5983/5564/6882/5565/1020/53615/6877/5516/1017/9891/5305/5883/25946/10111/207/22974/6749/545/8550/7316/6872/55615/6879/112858/10848/9099/2033/3065/91875/5527/5932/8851/5300/7156/138474/133746/10919/4193 155 Human_herpesvirus_8_type_P R-HSA-2467813 Separation of Sister Chromatids 178/5323 190/10654 5.258916928564809e-40 3.699648059245343e-38 1.3645505504118166e-38 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/113457/5683/1060/5699/5702/81027/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/5698/5692/5713/91687/119504/11243/10376/5710/7324/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/347733/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7280/1778/5516/5905/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/79023/55920/10735/10197/1781/7316/10213/4085/55166/5715/5701/5685/5686/79003/9126/9232/5527/9700/5716/701/57551/5693/5721 178 Human_herpesvirus_8_type_P R-HSA-9607240 FLT3 Signaling 232/5323 267/10654 5.270249837593351e-38 3.5310673911875454e-36 1.3023725162574048e-36 5295/5689/374/2674/4893/6711/2250/1437/71/5682/1844/5291/1850/1848/5526/817/84292/5908/3082/143471/2064/5705/8452/6776/4684/5709/9978/5695/1852/2668/22866/5605/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/1847/3563/9542/2885/6709/8660/8826/9846/5518/2252/4140/3845/5623/3265/4763/5696/5691/7314/5515/54106/5923/5718/818/57554/1839/5290/3667/8823/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/57761/5921/4902/2260/5528/3718/2249/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/80824/1445/5710/5719/6233/2266/2246/2251/2243/1843/6777/369/801/200734/5781/30849/8682/1846/11221/28956/805/5170/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/409/5706/1438/673/2676/8315/2263/4233/84078/5714/5688/5159/5687/5708/3084/5529/816/208/6654/5704/10718/3716/7311/7450/1956/60/5536/2549/5694/7529/5595/25759/5516/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10817/10197/54518/2254/7316/10213/152831/1950/3560/5289/3055/57731/26281/10818/5715/8437/10256/2261/5701/5685/2255/8649/53358/5686/2066/27006/5979/1742/5527/5716/88/5906/5155/9048/4254/5296/808/3559/5693/5721/5245/5156/284 232 Human_herpesvirus_8_type_P R-HSA-69306 DNA Replication 126/5323 127/10654 3.2761664171293532e-37 2.0952573404095455e-35 7.727990639448668e-36 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/143471/5705/5709/5422/9978/1869/4174/5695/84515/4998/5711/10926/5683/990/5699/5702/8900/51529/29945/51434/55388/84296/6117/29882/5001/10714/5558/5696/5691/7314/996/5718/6118/23594/5700/122706/5707/64785/23198/898/3978/5557/890/51433/9861/6502/5698/5692/5985/5713/119504/4175/5710/5984/7324/5719/64682/6233/23649/5424/4999/4172/5000/8318/246184/54107/4173/5706/8881/5425/5714/5111/51053/6119/5688/5687/5427/5708/81620/10393/1870/5704/29935/51343/23595/7311/25906/51659/5983/5694/4176/56655/1017/5684/5720/57804/8317/9837/5690/5717/9491/6500/10197/7316/10213/5426/4171/1871/5715/5701/5685/5686/5716/5981/5693/5721 126 Human_herpesvirus_8_type_P R-HSA-5684996 MAPK1/MAPK3 signaling 222/5323 255/10654 1.08877078707168e-36 6.660436945260234e-35 2.456585803324203e-35 5689/374/2674/4893/6711/2250/1437/71/5682/1844/1850/1848/5526/817/84292/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/22866/5605/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/1847/3563/9542/2885/6709/8660/8826/5518/2252/4140/3845/5623/3265/4763/3569/5696/5691/7314/3572/5515/5923/5718/818/57554/1839/3667/8823/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/4902/2260/5528/983/3718/2249/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/80824/1445/5710/5719/6233/2266/2246/2251/2243/1843/3570/369/801/200734/7297/5781/8682/1846/11221/28956/805/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/409/5706/1438/673/2676/8315/2263/4233/84078/5714/5688/5159/5687/5708/3084/5529/816/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/7529/5595/25759/5516/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10817/10197/54518/2254/7316/10213/152831/1950/3560/57731/26281/10818/5715/8437/10256/2261/5701/5685/2255/8649/53358/5686/2066/27006/5979/1742/5527/5716/88/5906/5155/9048/4254/808/3559/5693/5721/5245/5156/284 222 Human_herpesvirus_8_type_P R-HSA-69206 G1/S Transition 129/5323 131/10654 1.3480312528042186e-36 7.902833219564732e-35 2.9148219633003504e-35 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/4998/5711/5928/10926/5683/990/5699/5702/8900/55388/28227/5518/6117/5001/7465/5558/5696/5691/7314/5515/6241/5718/6118/23594/7027/5700/5707/898/91768/5934/5557/993/890/1876/983/9861/5519/6502/5698/10000/5692/5713/595/4175/5710/5719/6233/7298/23649/1719/1163/4999/4172/26271/1019/5000/8318/54107/4173/5706/286826/891/4331/5714/5111/51053/6119/5688/5687/91750/5427/5708/1874/81620/208/5704/29935/55957/23595/7311/5694/4176/5516/56655/1017/5684/5720/902/8317/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5933/5426/4171/5715/5701/5685/5686/3065/5716/1022/5693/5721/7083/132660 129 Human_herpesvirus_8_type_P R-HSA-5673001 RAF/MAP kinase cascade 216/5323 249/10654 3.381587251342332e-35 1.9031573050554645e-33 7.019463220681136e-34 5689/374/2674/4893/6711/2250/1437/71/5682/1844/1850/1848/5526/817/84292/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/22866/5605/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/1847/3563/9542/2885/6709/8660/8826/5518/2252/4140/3845/5623/3265/4763/5696/5691/7314/5515/5923/5718/818/57554/1839/3667/8823/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/4902/2260/5528/3718/2249/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/80824/1445/5710/5719/6233/2266/2246/2251/2243/1843/369/801/200734/8682/1846/11221/28956/805/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/409/5706/1438/673/2676/8315/2263/4233/84078/5714/5688/5159/5687/5708/3084/5529/816/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/7529/5595/25759/5516/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10817/10197/54518/2254/7316/10213/152831/1950/3560/57731/26281/10818/5715/8437/10256/2261/5701/5685/2255/8649/53358/5686/2066/27006/5979/1742/5527/5716/88/5906/5155/9048/4254/808/3559/5693/5721/5245/5156/284 216 Human_herpesvirus_8_type_P R-HSA-168254 Influenza Infection 147/5323 155/10654 5.735727644464164e-35 3.103911075292722e-33 1.1448233719517545e-33 3839/6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/116832/23225/6156/6143/5439/3836/6139/9972/3921/8021/7040/55746/6208/6170/3303/6203/402569/6147/6222/8106/9636/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/7514/1213/5610/1211/6188/6396/129401/200916/6122/6230/4928/2963/3838/5434/5903/6194/55706/7175/6166/5436/6136/6125/821/6232/6160/293/5611/6193/4927/6210/6229/6205/2962/10898/3840/140801/6235/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/5440/9349/4736/2926/51121/9631/6159/6217/5430/6152/51065/6141/79023/6123/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 147 Human_herpesvirus_8_type_P R-HSA-69620 Cell Cycle Checkpoints 246/5323 293/10654 6.765421583521193e-35 3.525536358523822e-33 1.3003324914915978e-33 5689/55839/11130/9134/83990/11065/6249/5682/9156/57060/9735/1763/7531/7486/7321/5526/10971/8697/9212/5982/7533/2810/147841/348995/11200/143471/472/57122/5705/1780/23122/5048/5709/4174/5695/57405/8655/84515/23279/4194/4998/5711/2491/4683/10926/5683/990/1060/165918/84126/5699/5702/8900/51529/29945/8924/11004/51434/55388/672/9184/5518/6117/29882/7334/5001/23332/7465/25909/51230/10726/81930/55746/5696/83695/5691/7314/996/5515/5718/6118/79682/10403/23594/25936/5700/122706/5707/51588/51720/3619/23198/63967/898/64105/7534/332/5528/993/116028/890/983/51433/9861/79902/3796/9656/5519/81565/5698/5692/5985/5713/91687/119504/11243/4175/5710/7157/5984/7324/83540/5719/64682/6233/7514/7158/54820/6396/64946/9793/5884/5810/140735/4999/220134/4172/80010/4928/5903/5000/8318/246184/55055/51512/1029/80776/1783/401541/7532/79172/4173/5706/9133/79980/6232/580/8881/11073/891/5501/641/5714/54821/6119/9183/3364/10524/5688/1062/699/5687/144715/5708/22919/5529/51143/1111/10393/5704/23595/7311/25906/5347/84643/5983/5694/4176/7529/1778/5516/1017/5905/5684/5720/54908/55143/5883/5525/25946/1058/991/79019/10111/8317/348235/80152/5690/1063/8379/5717/1027/9491/23421/545/79023/55920/10197/7336/29086/1781/7316/10213/4085/1026/4171/55166/5715/9088/7341/5701/5685/5686/995/79003/5527/5716/701/5932/9025/79184/57551/7156/5693/5721/4193 246 Human_herpesvirus_8_type_P R-HSA-69239 Synthesis of DNA 118/5323 119/10654 8.674216648768844e-35 4.358793866006344e-33 1.6076649653545266e-33 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/143471/5705/5709/5422/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/84296/6117/29882/5001/10714/5558/5696/5691/7314/996/5718/6118/23594/5700/122706/5707/64785/23198/898/3978/5557/890/51433/9861/6502/5698/5692/5985/5713/119504/4175/5710/5984/7324/5719/64682/6233/23649/5424/4999/4172/5000/8318/246184/54107/4173/5706/8881/5425/5714/5111/6119/5688/5687/5427/5708/81620/10393/5704/51343/23595/7311/25906/51659/5983/5694/4176/56655/1017/5684/5720/57804/9837/5690/5717/9491/6500/10197/7316/10213/5426/4171/5715/5701/5685/5686/5716/5981/5693/5721 118 Human_herpesvirus_8_type_P R-HSA-6807070 PTEN Regulation 135/5323 140/10654 1.2661892014106733e-34 6.143200711671784e-33 2.265812255155942e-33 1912/5689/3725/6591/5682/1822/1459/9112/6045/27327/80012/1460/143471/5705/5709/5695/1457/1911/4734/11060/5711/5928/10325/5683/23512/57332/5699/2444/5702/192669/1107/8975/5371/2475/1386/10670/4343/80351/64121/5696/5691/7314/5718/23186/5700/122706/5707/2146/51564/5594/84232/23198/9861/7101/81847/84733/57459/5698/10000/5692/5713/5710/3066/7157/5719/6233/331/8726/26523/7874/57521/23608/6015/28956/389541/9219/8535/5931/58528/5706/8658/5714/1108/2122/64223/10014/5688/5687/5708/54815/6009/208/5704/55004/57504/7311/648/5694/23466/53615/5595/27161/5684/8841/5720/5468/5978/10273/207/5690/57690/5717/9491/10197/192670/153129/7316/10213/57167/5715/1958/5701/5685/8649/5686/5728/6615/3065/23028/5987/23112/10542/5716/5693/5721 135 Human_herpesvirus_8_type_P R-HSA-68886 M Phase 312/5323 395/10654 8.473075159604989e-34 3.9738722498547396e-32 1.465693352170267e-32 114791/10844/23165/5689/55839/11130/11065/440145/6249/5579/5682/9735/7531/1459/11190/7321/91754/203068/5526/54801/51807/8697/5578/9212/10274/5861/5925/1460/147841/348995/79441/143471/10381/57122/5705/5116/1780/23122/23511/5048/5709/5695/57405/8655/1457/23279/9702/5711/2491/10112/7846/23225/7840/113457/5683/1060/5699/9663/11064/5702/5520/81027/51529/4001/29945/11004/23133/51434/9184/9972/5518/55844/55835/29922/8021/29882/23332/84930/25909/10726/81930/55746/93323/5696/5691/7314/996/5515/5718/79682/10403/79861/64151/25936/55869/5700/122706/5707/1454/2801/5594/3619/23198/64105/23310/332/10762/10051/5528/983/8548/51433/9861/79902/3796/8615/79959/5519/9883/81565/2029/7444/5698/5692/5713/80097/91687/119504/11243/10376/23397/5710/10540/85378/7324/2010/83540/64900/5719/64682/6233/23175/7514/54930/54820/113130/9493/6396/129401/1453/27229/64946/9793/140735/220134/84617/4928/26271/5903/55706/7175/11258/22981/246184/55055/8636/80776/1783/401541/7532/55125/10382/79172/121441/7277/5706/9133/79980/25836/6232/23047/8881/9814/653784/5885/23354/891/5501/9738/1639/5714/55722/4957/4927/5566/54821/81876/9183/5688/1062/699/5687/7283/347733/5708/22919/8243/10426/5529/22994/51143/1069/8086/10393/79648/5577/5704/7311/25906/10383/5347/54892/84790/84643/80184/5694/22897/6418/5108/7112/10592/7280/10806/29781/5595/1778/5516/4000/115106/4926/5905/22995/55559/5684/5720/54908/55143/9631/5525/10142/1058/991/79019/5862/348235/80152/5690/1063/8379/95681/5717/9491/140609/23244/23421/79023/55920/23636/10735/10197/7443/23141/1781/7316/10213/80321/10776/53371/26003/4085/9688/55166/10121/5715/84131/5701/5685/3320/8815/5686/79003/9126/9918/10733/4751/9232/23592/5527/9700/27175/80254/5716/701/57551/9662/55142/64689/8481/5693/5721/55755/8480 312 Human_herpesvirus_8_type_P R-HSA-168255 Influenza Life Cycle 137/5323 144/10654 4.227904579733777e-33 1.9189231431243305e-31 7.077612759961808e-32 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/116832/23225/6156/6143/5439/3836/6139/9972/3921/8021/55746/6208/6170/3303/6203/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/7514/1213/1211/6188/6396/129401/200916/6122/6230/4928/2963/5434/5903/6194/55706/7175/6166/5436/6136/6125/821/6232/6160/5611/6193/4927/6210/6229/6205/2962/140801/6235/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/5440/9349/4736/2926/51121/9631/6159/6217/5430/6152/51065/6141/79023/6123/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 137 Human_herpesvirus_8_type_P R-HSA-418594 G alpha (i) signalling events 316/5323 406/10654 5.299846058492509e-32 2.330276063843425e-30 8.59481614091055e-31 729230/2788/10316/6000/2780/1880/5158/7852/50833/29899/6385/5331/5726/338442/64805/2770/817/1237/1258/2550/5578/3000/50832/3354/2841/5582/4987/51289/259294/8644/2912/3576/6360/2775/5530/4985/2920/2921/1236/259295/107/6010/9568/2840/2831/5367/4988/6370/58191/6755/1524/643/2782/5499/339403/4023/2914/8843/2847/2833/9290/5518/9170/6382/187/6121/6750/259296/259289/5998/50835/2587/53829/814/2773/5515/2787/6387/54884/818/4544/4543/126006/10663/4889/9283/727/338398/117579/3579/84152/375790/23566/2358/5567/2916/259293/5594/5179/10681/112/8811/5573/348/56923/2832/5528/1259/27199/2826/8786/6376/165140/27198/111/5443/4836/3627/2792/9397/54429/6714/336/3361/6346/10988/5519/134/5588/1129/338328/51083/2785/2783/2784/1233/6366/5613/2861/2771/728/5332/10022/183/5580/6373/57121/1132/1814/80835/6357/196883/9672/115/8698/801/9934/50840/2791/50865/805/10803/2913/5145/3838/7276/351/11251/3352/8484/6351/6752/2781/1903/84539/6753/5568/3577/2918/5368/6754/131890/8862/301/56670/150/113/338/2868/335/2853/6751/186/53637/10645/5566/84254/10563/5540/1901/10287/5148/5733/23236/256933/10850/624/4852/816/2786/50838/5577/5473/4283/2239/11255/10874/83756/2719/56477/2986/1020/5141/259286/3350/129521/1234/109/9628/5516/151/57007/5533/815/26086/5321/9294/54331/283869/2817/5575/59345/63940/4986/8787/6374/5539/259287/2852/50836/1230/5532/846/4886/2919/51764/94235/114/5330/259290/6383/108/5196/2779/3827/5173/2357/55970/2778/6352/140/10768/346562/152/5957/6364/80834/259292/3949/2793/5030/5697/5576/3355/5534/3351/4035/6288/6372/50834/259285/79823/1385/5144/719/6363/2917/1268/50831/2359/50839/808/388531/5660/1815/1325/1232/1902/50837/10082/1269/59340/4887/2790/718/623 316 Human_herpesvirus_8_type_P R-HSA-168898 Toll-like Receptor Cascades 144/5323 155/10654 2.002196332013032e-31 8.536637088310107e-30 3.1485894471528703e-30 8454/3725/9252/4790/7321/1848/1785/6280/10333/4792/59307/177/1432/2244/929/3654/51135/6196/1759/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/54106/11035/8945/1326/5601/6283/5606/11213/8737/8767/5336/1849/29110/5594/6271/4214/28512/23118/841/8517/5528/7323/5970/7096/9261/5519/5598/4208/6195/10454/3661/6233/51311/10010/2266/2353/2243/8772/5600/5781/30849/5608/4791/671/1508/1846/3665/351/81793/7184/653509/3684/8411/330/51295/7098/338/79155/6279/8651/26052/64127/5602/3656/57162/695/7189/81622/7311/9641/6416/9450/51284/28511/5595/5516/23643/1147/1845/4064/6885/5604/10392/6500/246330/7099/4615/7100/7316/7335/1513/4205/5289/4793/5775/3146/7322/329/466/23291/114609/6288/2002/6285/5609/948/1520/1385/5599/353376/7097/3929/57161/3689/148022 144 Human_herpesvirus_8_type_P R-HSA-2262752 Cellular responses to stress 361/5323 479/10654 2.501908821367808e-31 1.0353487387248546e-29 3.818702937877181e-30 1912/23165/5689/3725/6782/9134/2077/11065/573/4790/5682/64344/7531/1915/11133/7321/51807/817/6045/8697/9530/23677/27327/80012/7295/5925/3091/348995/143471/472/10381/57122/5705/79813/3576/3313/1780/7001/23511/5709/9978/2114/1869/5695/3305/8655/84516/1911/832/23279/4194/1031/91582/5711/5928/1432/1387/4683/10325/7846/259217/23225/113457/5683/3309/23512/57332/5699/7428/5702/192669/9531/81027/8900/51529/4001/29945/8091/8131/2056/51434/2475/1032/3306/27000/1030/6196/9972/10670/23411/8021/4343/6117/6197/29882/3312/4217/54386/3569/64121/55746/5696/5691/7296/7314/51164/996/51182/5718/818/3303/7014/6118/5601/79861/2876/5606/7027/5700/122706/5707/2146/9550/2936/9114/5594/3308/84335/23198/898/10049/10013/27244/3337/10762/847/7323/890/5970/9261/6667/51433/9861/79902/5598/9883/2932/84733/529/5698/5692/5713/2877/119504/10376/6195/5710/3301/533/10540/7157/7324/5719/64682/6233/2353/8726/6396/1535/129401/5600/523/201163/26523/405/5608/3297/57521/140735/768/6015/28956/84617/4928/4688/1019/5903/83667/55706/7175/653361/5241/11258/9448/246184/112399/1029/1783/389541/25828/8535/84962/10382/93661/5931/58528/10294/55860/830/7013/7277/1051/1410/50488/5706/10671/8881/527/6774/1639/5714/4927/64223/6119/3552/10370/10524/5688/5687/57805/3310/2908/347733/5708/5602/7266/6009/51143/816/6648/8086/10393/1870/5704/3326/55004/51343/7311/367/25906/3397/2034/79400/57634/10383/84790/55662/648/5694/3304/23466/3456/2113/6416/10641/257202/7280/10728/829/2880/23523/5595/1778/1017/815/25913/5684/5720/9631/3159/7290/116835/10111/2878/7422/5690/57690/5717/1027/9491/545/79023/23636/10197/192670/10808/153129/3490/8550/29855/4306/1781/7316/10213/10935/53371/1026/9532/54205/2289/9588/9688/10121/7415/1871/6647/8994/7322/5715/2882/5701/112398/5685/8649/3320/65057/5686/2033/1021/6767/25842/493869/8453/50507/23135/10963/22824/57600/23112/5609/10542/4689/5716/9529/5599/54583/5052/1536/96459/5693/5721/55466/2288/5034/8480/10919/51382/318/4193/2950/23043 361 Human_herpesvirus_8_type_P R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 356/5323 473/10654 1.0660440655030673e-30 4.285497143322331e-29 1.5806307497534204e-29 5295/374/5777/627/3643/9252/4893/857/2250/2670/5335/71/5579/5770/5291/26469/1848/10653/5578/1785/5908/3082/51741/23385/2064/535/1280/1289/54845/5431/8829/6696/6776/5435/3688/5433/5753/5327/7423/4734/10413/5605/3910/8569/5898/1432/3717/55824/145957/2534/9475/3690/9965/5439/2264/5603/3630/6456/83737/6868/7072/4145/9542/30011/2885/2475/8660/6093/163/7073/6196/9846/1759/5518/8440/2252/8874/9564/6197/3845/3265/1399/3071/8877/5062/4486/10252/51231/5829/7314/5879/5515/6387/5607/54106/26999/1839/3918/161/5290/3667/8823/6678/2065/5340/3815/5567/10006/3911/9550/1849/1284/2060/9114/5594/2069/8074/23118/57761/5921/6778/2260/5438/348/5528/9306/1500/3185/11059/102/9261/2249/6714/2099/5664/2248/1447/5519/5598/4208/4670/2567/4909/2321/2247/4914/529/10810/10000/9146/6455/2335/6195/3728/8471/1445/533/3925/6233/7525/7410/5580/2324/7409/2246/23191/3685/1292/2251/3932/1213/3791/1729/1211/29924/1535/5600/6777/1175/523/6300/801/200734/5781/30849/5663/5725/1291/10787/1846/253260/805/25920/5170/4908/1173/4688/2963/5434/5590/6464/85440/653361/5241/2904/6461/5747/5782/7424/5436/5568/2322/7074/3315/2241/10451/4318/382/1277/160/3912/1793/673/527/6774/2263/4233/10152/6772/8651/26052/64223/5566/2962/1003/8503/5795/2889/10163/5159/4067/3084/55845/5063/5771/1111/998/7058/3481/2886/3913/208/6654/83464/5867/10718/79109/7311/2185/387/1956/60/55851/2549/51107/5058/1020/5432/3480/22916/11140/4916/7529/63916/5595/25759/5516/1845/10253/5440/1282/8065/685/23543/558/4915/1495/5604/1499/5430/10048/10273/207/7422/10458/3178/8817/10817/5441/58513/2254/4686/7316/152831/1950/9611/9047/4205/5289/57498/55615/3915/10768/26281/10818/1281/8936/2261/867/5437/466/2255/53358/3320/4846/4803/2002/2066/27006/6285/1742/1398/3187/4689/5774/1385/9844/5228/5906/3479/5155/4254/8851/5296/5581/581/808/10076/1536/7057/1278/11033/10254/51382/5156/2242 356 Human_herpesvirus_8_type_P R-HSA-5696398 Nucleotide Excision Repair 109/5323 111/10654 1.2891153342174508e-30 5.038292431233204e-29 1.8582861396760333e-29 2074/10445/5982/6613/7507/5431/5435/9978/5433/85015/10980/57654/2965/5439/10987/2067/2967/6612/6117/7334/10714/91603/7314/6118/83444/404672/9557/3150/86/5438/3978/1643/29844/5985/10920/2068/5984/54891/6233/93973/8607/7874/5424/5886/8451/8554/10450/5434/5436/7515/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/142/125476/2071/1069/7329/51426/2873/7311/3980/60/8533/5983/10038/5432/51138/7528/56655/9318/6917/5440/902/27339/5430/57804/5441/7336/2072/54778/7316/64708/5426/283899/7341/4798/5437/79913/10401/54617/2033/2968/56949/5887/9716/2073/5981/1022/8178/50813/7508 109 Human_herpesvirus_8_type_P R-HSA-162906 HIV Infection 199/5323 233/10654 1.738431889157932e-30 6.610739643365433e-29 2.4382558217776972e-29 6884/23165/6875/5689/2237/7852/162/5682/6874/1174/348995/143471/57122/5705/3981/5431/23511/5435/5709/9978/5433/5695/2960/292/567/23279/5711/23327/29082/8732/23225/5683/2965/2534/27183/5699/5439/5702/6873/3836/163/9972/6881/2967/51616/8021/11198/904/51497/5062/55746/5696/5691/7314/5879/5718/8945/161/25978/5700/51160/122706/5707/2959/7518/23198/404672/10015/5438/3978/10762/79720/51534/4836/926/9397/9861/79902/11168/9883/83860/51510/5698/5692/5713/5710/2068/5478/5719/6233/7514/1025/3932/6396/129401/6883/7936/1175/6829/2957/940/25920/60489/1173/4928/2963/5434/5903/55706/7175/5436/6878/4869/5706/160/293/920/4331/5714/4927/8148/2966/2962/5688/54457/8812/5687/5708/128866/905/2071/5901/8086/5704/7311/6880/6908/7251/5694/1104/2547/6882/2961/5432/22916/1234/6877/5905/3837/6917/5440/164/5684/8065/5720/902/9631/3159/5430/5690/7520/5717/9491/6500/6749/79023/5441/23636/10197/7469/919/4686/7316/10213/6872/53371/3055/9688/6879/9150/5715/5701/2958/5437/5685/8815/5686/6827/2968/5716/9844/375/138474/1022/5693/5721/8178/8480/291 199 Human_herpesvirus_8_type_P R-HSA-168273 Influenza Viral RNA Transcription and Replication 127/5323 134/10654 2.9484675272999098e-30 1.0917088976081509e-28 4.026577537282149e-29 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/116832/23225/6156/6143/5439/6139/9972/3921/8021/55746/6208/6170/6203/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/6188/6396/129401/200916/6122/6230/4928/2963/5434/5903/6194/55706/7175/6166/5436/6136/6125/6232/6160/5611/6193/4927/6210/6229/6205/2962/140801/6235/6181/8086/7311/6223/25873/9045/6187/5432/6168/6157/6137/6144/5440/9349/4736/2926/51121/9631/6159/6217/5430/6152/51065/6141/79023/6123/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 127 Human_herpesvirus_8_type_P R-HSA-927802 Nonsense-Mediated Decay (NMD) 112/5323 115/10654 3.213902036338217e-30 1.1304900412819676e-28 4.1696150103019505e-29 6158/9887/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/55629/6169/6175/6218/65109/6173/6167/116832/6156/6143/5520/6139/23381/5518/3921/6208/6170/5515/6203/6147/6222/26019/2935/6134/22794/6155/4116/6231/6142/23521/1981/6207/6233/6188/23049/5976/200916/6122/6230/6194/2107/6166/56006/6136/6125/6232/6160/55110/6193/6210/6229/6205/55181/140801/6235/6181/9939/7311/6223/25873/23708/9045/6187/65110/6168/22916/6157/6137/10921/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/4686/6209/11224/6165/6130/6204/6228/55802/6124/6189/23293/9775/6135/6201/6161/6133 112 Human_herpesvirus_8_type_P R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 112/5323 115/10654 3.213902036338217e-30 1.1304900412819676e-28 4.1696150103019505e-29 6158/9887/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/55629/6169/6175/6218/65109/6173/6167/116832/6156/6143/5520/6139/23381/5518/3921/6208/6170/5515/6203/6147/6222/26019/2935/6134/22794/6155/4116/6231/6142/23521/1981/6207/6233/6188/23049/5976/200916/6122/6230/6194/2107/6166/56006/6136/6125/6232/6160/55110/6193/6210/6229/6205/55181/140801/6235/6181/9939/7311/6223/25873/23708/9045/6187/65110/6168/22916/6157/6137/10921/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/4686/6209/11224/6165/6130/6204/6228/55802/6124/6189/23293/9775/6135/6201/6161/6133 112 Human_herpesvirus_8_type_P R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 123/5323 129/10654 4.2125354694407416e-30 1.445618879391006e-28 5.331912673772236e-29 8454/3725/9252/4790/7321/1848/1785/10333/4792/59307/177/1432/929/3654/51135/6196/1759/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/1326/5601/6283/5606/11213/8737/8767/5336/1849/29110/5594/4214/28512/23118/841/8517/5528/7323/5970/7096/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/671/1846/3665/351/653509/3684/330/51295/79155/8651/26052/64127/5602/3656/57162/695/7189/7311/9641/6416/9450/28511/5595/5516/23643/1147/1845/4064/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/5775/3146/7322/329/466/23291/114609/6288/2002/6285/5609/948/1385/5599/353376/7097/3929/57161/3689/148022 123 Human_herpesvirus_8_type_P R-HSA-376176 Signaling by ROBO receptors 188/5323 218/10654 5.027212288778018e-30 1.6841161167406361e-28 6.211568066084119e-29 6158/5689/6138/6227/7852/6206/6234/6191/6128/5682/6132/10298/6129/6176/5578/6224/6146/6154/26986/143471/6202/5705/6169/8829/23122/5709/9978/6175/6218/5695/65109/6173/6167/5711/116832/1605/5683/6156/5699/6143/5702/6585/6139/10487/8440/3921/23332/5062/6208/5696/6170/5691/7314/5879/6387/5718/25/6203/6147/5700/122706/5707/5567/6222/23198/27/26019/2935/6134/6091/22794/6155/4116/6714/6231/9861/6142/23521/10486/5698/5692/5713/1981/5710/6207/5719/6233/6188/200916/6122/6230/6194/2107/9423/6166/56924/6136/5568/6125/5706/3670/6232/6160/55110/5714/6193/6210/6229/6205/5566/4650/5688/5687/5708/5063/140801/6235/6181/998/9939/6654/5704/7311/6223/25873/387/6655/23708/5694/5058/9045/6187/65110/6168/22916/6157/6137/10921/6144/55740/23032/5684/9349/4736/5720/51121/2817/6159/6217/6152/5690/5532/5717/9491/51065/6141/6123/10197/6164/4686/7316/10213/5216/6209/11224/6165/6130/5715/6204/5701/6228/5576/5685/5686/7408/6124/8453/5716/23380/1630/6189/9775/6135/6201/6161/5693/5721/6133 188 Human_herpesvirus_8_type_P R-HSA-8957275 Post-translational protein phosphorylation 106/5323 108/10654 1.0086296054295381e-29 3.300329894975256e-28 1.2172690219749384e-28 56955/4240/3270/9210/10272/2153/7857/29106/91851/6696/51156/1435/265/11098/10130/2200/80341/375056/1114/720/10117/3956/3569/54972/2519/8720/7018/10618/11167/813/5179/8074/51246/348/4924/3484/102/8614/336/6694/4148/174/57104/721/2335/7466/116519/2266/51280/7076/2243/84141/3488/8542/4221/351/4052/7184/56975/334/3912/338/64856/335/5611/197/3053/3895/5624/1000/54757/8404/255738/3913/652/57719/147111/2719/3487/3371/54587/401138/3486/7425/6383/3827/3490/5589/2621/3915/5768/1471/1462/10232/462/3698/5265/1758/258/11320/5954/213/10970/5034/1356/718 106 Human_herpesvirus_8_type_P R-HSA-9010553 Regulation of expression of SLITs and ROBOs 153/5323 171/10654 1.3872491834506105e-28 4.436044547988657e-27 1.6361575297635193e-27 6158/5689/6138/6227/6206/6234/6191/6128/5682/6132/6129/6176/6224/6146/6154/26986/143471/6202/5705/6169/5709/9978/6175/6218/5695/65109/6173/6167/5711/116832/1605/5683/6156/5699/6143/5702/6585/6139/3921/6208/5696/6170/5691/7314/5718/6203/6147/5700/122706/5707/6222/23198/26019/2935/6134/6091/22794/6155/4116/6231/9861/6142/23521/5698/5692/5713/1981/5710/6207/5719/6233/6188/200916/6122/6230/6194/2107/6166/6136/6125/5706/3670/6232/6160/55110/5714/6193/6210/6229/6205/5688/5687/5708/140801/6235/6181/9939/5704/7311/6223/25873/23708/5694/9045/6187/65110/6168/22916/6157/6137/10921/6144/23032/5684/9349/4736/5720/51121/6159/6217/6152/5690/5717/9491/51065/6141/6123/10197/6164/4686/7316/10213/6209/11224/6165/6130/5715/6204/5701/6228/5685/5686/6124/8453/5716/6189/9775/6135/6201/6161/5693/5721/6133 153 Human_herpesvirus_8_type_P R-HSA-8953897 Cellular responses to external stimuli 364/5323 493/10654 1.573350618881855e-28 4.919342935037266e-27 1.8144136961608293e-27 1912/23165/5689/3725/6782/9134/2077/11065/573/4790/5682/64344/7531/1915/11133/7321/51807/817/6045/8697/9530/23677/27327/80012/7295/5925/3091/348995/143471/472/10381/57122/5705/79813/3576/3313/1780/7001/23511/5709/9978/2114/1869/5695/3305/8655/84516/1911/832/23279/4194/1031/91582/4493/5711/5928/1432/1387/4683/10325/7846/259217/23225/113457/5683/3309/23512/57332/5699/7428/5702/192669/9531/81027/8900/51529/4001/29945/8091/8131/2056/51434/2475/1032/3306/27000/1030/6196/9972/10670/23411/8021/4343/6117/6197/29882/3312/4217/54386/3569/64121/55746/5696/5691/7296/7314/51164/996/51182/5718/818/3303/7014/6118/5601/79861/2876/5606/7027/5700/122706/5707/2146/9550/2936/9114/5594/3308/84335/23198/898/10049/10013/27244/3337/10762/847/7323/890/5970/9261/6667/51433/9861/79902/5598/9883/2932/84733/529/5698/5692/5713/2877/119504/10376/6195/5710/3301/533/10540/7157/7324/5719/64682/6233/2353/8726/6396/1535/129401/5600/523/201163/26523/405/5608/3297/57521/140735/768/6015/28956/84617/4928/4688/1019/5903/83667/55706/7175/653361/5241/11258/9448/246184/112399/1029/1783/389541/25828/8535/84962/10382/93661/5931/58528/10294/55860/830/7013/7277/1051/1410/50488/5706/10671/8881/527/6774/1639/5714/4927/64223/6119/3552/10370/10524/5688/5687/57805/3310/2908/347733/5708/5602/7266/6009/51143/816/6648/8086/10393/1870/5704/3326/55004/51343/7311/367/25906/3397/2034/79400/57634/10383/84790/55662/648/5694/3304/23466/3456/2113/6416/10641/257202/7280/10728/829/2880/23523/5595/1778/1017/815/25913/5684/5720/9631/3159/7290/116835/10111/4502/2878/7422/5690/57690/5717/1027/9491/545/79023/23636/10197/192670/10808/153129/3490/8550/29855/4306/1781/7316/10213/10935/53371/1026/9532/54205/2289/9588/9688/10121/7415/1871/6647/8994/7322/5715/2882/5701/112398/5685/8649/3320/65057/5686/2033/1021/6767/25842/493869/8453/50507/23135/10963/22824/57600/23112/5609/10542/4689/5716/9529/4520/5599/54583/5052/1536/96459/5693/5721/55466/2288/5034/8480/10919/51382/318/4193/2950/23043 364 Human_herpesvirus_8_type_P R-HSA-5357801 Programmed Cell Death 160/5323 181/10654 2.03158596160625e-28 6.214003147782595e-27 2.291926496731994e-27 5689/5682/4976/7531/356/10971/10059/7533/2810/143471/5705/5709/1869/5695/8655/660/5711/90249/836/5683/929/324/5699/9414/5702/90427/4001/3836/6709/6093/840/7159/26060/637/5062/5696/5691/7314/578/23368/5718/2934/11035/22985/219699/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/100506658/7082/5339/4836/8797/9861/28988/10134/22900/999/5588/598/5698/10000/5692/708/5713/5710/3002/7157/5719/6233/5580/1613/839/8772/331/8717/57099/317/8743/140735/1828/5747/1029/572/7532/330/5706/1829/6774/5366/5714/5688/5687/1832/5708/8837/8626/197259/208/5704/7311/7161/5694/8795/3148/7529/5595/23643/4000/5533/27113/3837/1676/596/5684/5720/7186/51765/1499/10018/842/207/5690/5717/9491/355/10197/7099/9500/7316/10213/54205/3146/5715/23604/5701/329/5685/5686/5534/4137/5716/1677/1630/581/5599/353376/7431/5693/5721/6304/148022 160 Human_herpesvirus_8_type_P R-HSA-3858494 Beta-catenin independent WNT signaling 134/5323 146/10654 6.822643034552818e-28 2.0424380318331523e-26 7.533175847781723e-27 2788/5689/2780/5158/5579/5682/5331/5578/1212/5582/27327/143471/5705/2775/5530/5709/5695/5881/5711/5683/5699/2782/5702/192669/57216/1855/6932/163/4343/5593/3845/5696/5691/4920/7314/5879/2787/5718/51176/2535/161/51701/5700/122706/5707/1856/8322/23198/10681/7471/83439/8323/2792/9861/8321/7481/5698/5880/5692/5713/2785/2783/2784/5710/5719/6233/7474/1857/1213/1211/7855/1175/26523/801/2791/7976/805/5145/1173/4772/409/5706/160/5714/6934/5688/5687/5148/23236/5708/2786/5704/7311/387/5694/57154/27161/815/5684/5720/54331/6885/1499/59345/5690/5532/57690/5717/9491/50855/51764/94235/5330/10197/192670/64750/7316/10213/55970/5216/5715/5701/2793/5685/5686/5534/23112/23513/5716/808/5693/5721/6259/2790 134 Human_herpesvirus_8_type_P R-HSA-373076 Class A/1 (Rhodopsin-like receptors) 263/5323 335/10654 7.925591720972004e-28 2.3231890732099187e-26 8.56867701412105e-27 729230/10316/2149/23620/1880/7852/10161/338442/64805/1237/5734/3354/2841/4987/51289/2150/3060/3576/6360/2798/5737/338557/4985/2920/3061/2921/1236/6010/2840/2831/5367/5028/4988/6370/58191/6755/6866/1524/94233/643/5029/2867/185/339403/8843/64106/2847/2833/6347/9290/9170/187/6750/2587/53829/8111/6387/4544/4543/2922/10663/4889/9283/727/1909/5732/117579/3579/6375/23566/2358/1131/6846/5179/27334/27202/5021/6865/2797/8811/56923/2832/2693/27199/2826/6376/165140/27198/7201/5443/3627/3361/6346/553/257313/134/3814/10800/2863/1129/51554/51083/2829/1233/6366/1241/2861/728/10022/183/6373/57121/4922/5731/2865/1132/1814/3362/6357/552/2925/8698/9934/2151/6869/2147/1813/50865/10886/2837/10803/146/3357/351/11251/8477/84432/3352/8484/2828/3062/1907/148/6351/6863/6752/1903/84539/6753/3577/594857/5368/6754/6915/8862/10911/301/5032/56670/150/2853/29933/6751/5020/4935/887/4829/186/53637/60675/10563/5540/2864/1901/5733/256933/7200/5729/10850/624/2796/4852/4828/680/5473/4283/1910/6870/128674/11255/885/10874/84634/147/6356/56477/387129/3350/129521/1234/151/57007/1238/3356/84109/9294/4923/1128/283869/4986/6374/5539/2852/1230/3358/4886/2919/1908/5196/3827/5173/2357/6352/57105/1133/140/3269/6348/886/2862/152/1906/6364/5031/8620/5030/5697/56413/3355/3351/6288/6372/719/6363/1268/2359/347148/2846/5660/1815/1325/1232/4295/1902/551/154/9002/1269/59340/5724/4887/718/623 263 Human_herpesvirus_8_type_P R-HSA-109581 Apoptosis 157/5323 178/10654 1.17130557157138e-27 3.3633202840835344e-26 1.2405019264977237e-26 5689/5682/4976/7531/356/10971/10059/7533/2810/143471/5705/5709/1869/5695/8655/660/5711/90249/836/5683/929/324/5699/9414/5702/90427/4001/3836/6709/6093/840/7159/26060/637/5062/5696/5691/7314/578/23368/5718/2934/22985/219699/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/100506658/7082/5339/4836/8797/9861/28988/10134/22900/999/5588/598/5698/10000/5692/708/5713/5710/3002/7157/5719/6233/5580/1613/839/8772/331/8717/57099/317/8743/140735/1828/5747/1029/572/7532/5706/1829/6774/5366/5714/5688/5687/1832/5708/8837/8626/208/5704/7311/7161/5694/8795/3148/7529/5595/23643/4000/5533/27113/3837/1676/596/5684/5720/7186/51765/1499/10018/842/207/5690/5717/9491/355/10197/7099/9500/7316/10213/54205/3146/5715/23604/5701/329/5685/5686/5534/4137/5716/1677/1630/581/5599/353376/7431/5693/5721/6304/148022 157 Human_herpesvirus_8_type_P R-HSA-8856688 Golgi-to-ER retrograde transport 124/5323 133/10654 1.3211492964528038e-27 3.71771412021819e-26 1.3712139013710155e-26 11014/64837/11127/51807/53407/3798/5861/10381/1780/5048/8655/84516/832/285643/55738/10112/636/64147/7846/113457/2590/51226/81027/11004/10749/81930/54732/51164/60561/113220/79861/3797/29127/55605/23299/377/8398/1315/3796/5870/124602/11316/55614/89953/56992/8729/23423/10376/1314/10540/3835/147700/3833/378/9493/26286/26958/140735/10959/3831/84364/22820/84617/11258/1783/55850/9585/10382/93661/55860/830/3832/7277/10671/9554/23303/1639/8775/26153/81876/9183/1062/11015/146909/347733/662/90990/51143/23046/10383/24137/84790/84643/10945/5049/51594/22920/7280/829/1778/55582/5321/9371/51014/23095/5050/63908/1781/10121/6836/547/51560/8774/10972/381/4905/3834/9276/55083/3799/375/221458/22818/372 124 Human_herpesvirus_8_type_P R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 113/5323 119/10654 2.9626565293071277e-27 8.1734465426179e-26 3.0146329596458496e-26 5244/84498/79718/9441/34/892/27063/1543/54600/5469/9612/27242/11010/1387/6907/84246/26230/4801/29841/50486/2274/1376/55588/10499/23054/9575/1581/85441/9282/23097/10062/7296/96764/51129/57761/5465/9915/2222/10025/3157/6667/23309/336/3156/6604/80205/9439/3992/4199/123/2168/183/116519/6257/3158/376497/9412/9969/405/54797/55090/4899/1374/9440/6721/51/9862/23179/9442/406/19/335/4800/1024/9968/10001/23389/9443/211/9477/1579/25942/51586/400569/6822/80306/8841/5468/29079/4802/4862/90390/6720/6837/9611/2874/81857/2033/8800/9967/6256/51003/7376/10498/948/112950/196/4520/8202/8648/2180/10891/219541 113 Human_herpesvirus_8_type_P R-HSA-9020702 Interleukin-1 signaling 100/5323 103/10654 1.073366065093302e-26 2.9003880742154443e-25 1.0697574687376757e-25 8454/5689/4790/5682/8878/143471/5705/5709/9978/5695/4792/177/5711/5683/5699/5702/3654/51135/7334/3551/5696/5691/7314/257397/5718/8945/1326/6283/11213/5700/122706/5707/8767/23198/28512/23118/8517/5970/9861/5698/5692/5713/5710/10454/5719/6233/5608/4791/3557/351/54472/5706/79155/5714/64127/3552/5688/5687/5708/3656/57162/7189/5704/7311/5694/6416/3554/28511/3556/1147/5684/5720/6885/5604/4215/10392/5690/3553/5717/9491/6500/246330/10197/4615/7316/10213/7335/4793/3146/5715/5701/23291/5685/5686/6288/6285/5716/57161/5693/5721 100 Human_herpesvirus_8_type_P R-HSA-1989781 PPARA activates gene expression 111/5323 117/10654 1.092541349917687e-26 2.9003880742154443e-25 1.0697574687376757e-25 5244/84498/79718/9441/34/892/27063/1543/54600/5469/9612/27242/11010/1387/6907/84246/26230/4801/29841/50486/2274/1376/55588/10499/23054/9575/1581/85441/9282/23097/10062/7296/96764/51129/57761/5465/9915/2222/10025/3157/6667/336/3156/6604/80205/9439/3992/4199/123/2168/183/116519/6257/3158/376497/9412/9969/405/54797/55090/4899/1374/9440/6721/51/9862/23179/9442/406/19/335/4800/1024/9968/10001/23389/9443/211/9477/1579/51586/400569/6822/80306/8841/5468/29079/4802/4862/90390/6720/6837/9611/2874/81857/2033/8800/9967/6256/51003/7376/10498/948/112950/196/4520/8202/8648/2180/10891/219541 111 Human_herpesvirus_8_type_P R-HSA-6798695 Neutrophil degranulation 352/5323 480/10654 1.1369614380258846e-26 2.9624161913007774e-25 1.0926354560365714e-25 8773/7130/9798/1727/5689/8804/5777/5806/4893/9218/4790/3240/960/1823/1511/5657/57826/1915/4057/3107/203068/5175/5199/383/8836/2268/5908/1460/1265/29108/23385/10394/54509/6280/5788/535/10577/5709/10576/1509/5695/2896/4126/10562/8655/567/290/7133/154664/3106/3074/3417/3043/388698/1667/2548/1432/11010/3920/5476/8904/5683/929/201294/2588/80142/2444/23200/5702/566/9961/51552/10075/56729/10487/6947/684/6709/6093/160364/8826/9522/4282/2219/3608/2720/3312/3071/387263/2665/126014/51719/1654/967/2519/6037/5879/51316/2717/5718/1992/3303/58485/2934/80331/57554/64333/56954/161/6283/56888/3579/94103/5707/2358/3848/823/427/353189/5594/4831/23406/4680/5787/6727/127829/7414/10533/55754/4257/326624/847/2517/25852/3934/8895/5834/9545/1315/102/116844/4069/9861/5870/410/411/28988/226/2821/978/55832/968/5713/1/2495/3614/3728/10043/4125/5478/5719/374395/5328/728/5580/23191/3685/302/634/1729/9145/5236/25797/6036/1535/2040/230/317/2990/401258/5663/7879/671/1508/28956/10450/7077/25801/1828/3903/23352/7276/5284/83858/4332/1938/8635/51125/51646/1650/3684/79888/387921/3163/54472/3577/55860/1378/2760/5864/4318/3958/79980/23317/5836/6993/11240/10321/6616/5329/966/5611/84061/1116/527/6279/54918/4048/5337/210/10092/5795/197/140885/2171/3310/2352/1832/5708/55313/3615/11314/820/51143/4860/6386/27180/10788/8993/8778/5473/3326/10857/55004/10097/3916/240/10383/387/10396/5049/4317/51806/80184/1476/3304/2547/8673/10493/1075/114790/1778/10694/2512/3837/10890/5036/8621/5005/5315/8876/23197/1991/10120/6317/7520/5717/2919/5004/1118/1604/25840/1512/2357/10213/4718/6278/5547/932/2799/5768/1471/9588/29952/7415/3146/79792/4353/5701/6836/9342/8649/5265/3320/5686/388697/23593/391/175/25798/5873/1088/150372/23071/5878/2683/5646/948/1520/945/1675/719/93100/47/5906/81567/10855/3687/353376/124583/7097/5660/2212/1536/10970/3689/961/2207/5724/51382/2950/718 352 Human_herpesvirus_8_type_P R-HSA-2682334 EPH-Ephrin signaling 91/5323 92/10654 1.2005728687735375e-26 3.016439332793513e-25 1.1125609479423948e-25 71/2042/1947/1212/23385/2051/2045/10094/2050/285220/79784/2047/2534/9475/1948/4628/8976/6093/163/284656/8997/1759/8440/8874/3265/5062/5879/1072/161/10093/5921/2046/6453/4313/2041/102/6714/5664/1943/2043/7525/1942/7410/1213/1211/1175/25791/10109/5663/64283/1173/2904/5747/7074/1949/10627/1945/10451/4318/160/2049/8218/10092/4067/2044/5063/6386/998/2048/83464/10097/387/60/55851/51107/5058/4629/3984/28964/4627/3985/6383/10398/10552/4637/1946/10096/103910/1944/10095/1969 91 Human_herpesvirus_8_type_P R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 91/5323 92/10654 1.2005728687735375e-26 3.016439332793513e-25 1.1125609479423948e-25 6884/6875/5563/83990/9156/1763/1459/7486/6874/9212/5982/1460/11200/472/53632/28996/1457/6790/4194/1432/4683/84126/8900/6873/672/6881/51616/6117/11198/83695/7314/1263/6118/51422/116028/890/83860/5985/7157/5984/6233/5600/6883/5884/5810/26155/80010/8445/204851/6878/580/11073/641/8148/6119/3364/5571/10524/54457/144715/6794/94241/1111/7311/5562/6880/6908/5983/5564/6882/5565/1020/6877/1017/9891/5883/10111/22974/6749/545/8550/7316/6872/6879/112858/5932/8851/5300/7156/138474/4193 91 Human_herpesvirus_8_type_P R-HSA-446652 Interleukin-1 family signaling 128/5323 140/10654 2.792694982368776e-26 6.893547088057663e-25 2.5425644068472887e-25 8454/834/5689/5777/4790/5682/1511/26469/5783/27178/8878/143471/5705/5709/9978/5695/4792/59307/3606/177/5711/4088/5683/84867/5699/5702/3654/51135/7334/3551/5696/5691/7314/3596/257397/5718/8945/1326/6283/90865/11213/5700/122706/5707/8767/29110/23198/28512/23118/8517/3565/5970/8807/8809/9861/5698/5692/5713/5710/10454/5719/6233/5781/5608/4791/3557/351/5782/54472/5706/79155/6774/5780/5714/64127/3552/5688/5687/5708/3656/57162/5771/7189/5704/7311/240/5694/6416/3554/28511/3556/1147/5778/5684/5720/6885/5604/4215/10392/5690/3553/5717/9491/6500/25930/246330/10197/4615/26525/7316/10213/7335/4793/5775/3146/5715/5701/23291/5685/5686/6288/6285/5716/5599/5784/57161/5693/5721 128 Human_herpesvirus_8_type_P R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 106/5323 111/10654 2.968056775382769e-26 7.200096349937164e-25 2.655629746395109e-25 6158/6138/6227/6206/1965/6234/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/116832/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/200916/6122/1968/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 106 Human_herpesvirus_8_type_P R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 84/5323 84/10654 3.4884745417371465e-26 8.319124881735873e-25 3.0683638698954744e-25 10445/5982/6613/7507/9978/85015/10980/2965/10987/2067/2967/6612/6117/7334/10714/7314/6118/83444/404672/9557/86/3978/1643/29844/5985/10920/2068/5984/54891/6233/93973/8607/5424/5886/8451/8554/7515/54107/8450/4331/5425/5111/2966/6119/5427/1642/142/125476/2071/1069/7329/51426/2873/7311/3980/60/8533/5983/10038/51138/7528/56655/9318/902/57804/7336/2072/54778/7316/64708/5426/283899/7341/4798/79913/10401/54617/2968/5887/2073/5981/1022/50813/7508 84 Human_herpesvirus_8_type_P R-HSA-69052 Switching of origins to a post-replicative state 89/5323 90/10654 4.786059266106181e-26 1.1223308979018993e-24 4.139521435421662e-25 8454/5689/9134/11065/5682/7321/8697/143471/5705/5709/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/29882/5001/5696/5691/7314/996/5718/23594/5700/122706/5707/23198/898/890/51433/9861/6502/5698/5692/5713/119504/4175/5710/7324/5719/64682/6233/4999/4172/5000/246184/4173/5706/8881/5714/5688/5687/5708/81620/10393/5704/51343/23595/7311/25906/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 89 Human_herpesvirus_8_type_P R-HSA-416476 G alpha (q) signalling events 182/5323 217/10654 5.932699743553253e-26 1.3684112359310536e-24 5.047145769752812e-25 5295/2788/10316/2149/23620/4893/10161/5331/5578/2150/3060/5583/2769/2798/5737/338557/3061/2911/2840/5367/5028/6866/94233/5029/2782/2867/2776/185/2885/6196/64106/2847/8997/9170/6197/3845/3265/5998/8111/2787/2922/1839/5290/1909/6375/23566/2358/1131/6846/5594/27334/10681/5021/6865/2797/56923/2693/7201/2792/553/257313/5598/3814/10800/5588/2863/2785/6195/2783/2784/2829/222545/8525/1241/5332/183/5580/57121/115557/4922/5731/2865/552/2925/2151/6869/2791/2147/10886/2520/2837/146/3357/351/8477/84432/2828/3062/1907/148/7204/6863/84539/594857/6915/10911/301/5032/2642/29933/5020/4935/887/4829/60675/8503/2864/10287/23236/7200/624/2641/2796/4828/695/2786/680/6654/1910/6870/128674/885/1956/10874/84634/147/387129/129521/5595/3356/84109/54331/4923/1128/59345/1606/846/3358/1908/51764/94235/5330/3827/55970/57105/1133/4314/3269/2767/886/2862/1906/5031/8620/2793/56413/6288/2869/1385/5296/5581/347148/2846/9630/4295/1902/551/9002/2915/5724/2790/623 182 Human_herpesvirus_8_type_P R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 93/5323 95/10654 7.290269702243505e-26 1.6281602335010492e-24 6.005184566760314e-25 8454/3725/9252/4790/1848/10333/4792/59307/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/11213/8767/1849/5594/4214/28512/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/51295/79155/8651/64127/5602/3656/57162/695/7189/7311/6416/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/57161 93 Human_herpesvirus_8_type_P R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 93/5323 95/10654 7.290269702243505e-26 1.6281602335010492e-24 6.005184566760314e-25 8454/3725/9252/4790/1848/10333/4792/59307/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/11213/8767/1849/5594/4214/28512/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/51295/79155/8651/64127/5602/3656/57162/695/7189/7311/6416/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/57161 93 Human_herpesvirus_8_type_P R-HSA-500792 GPCR ligand binding 342/5323 468/10654 1.8030643367284138e-25 3.963924252776372e-24 1.462024207248533e-24 729230/2788/10316/2149/23620/1880/7852/7478/10161/50833/5726/338442/64805/1237/5734/2550/50832/3354/2841/4987/51289/259294/2150/3060/2912/3576/6360/2798/5737/338557/4985/2920/3061/2921/1236/259295/799/6010/9568/2911/2840/2831/5367/5028/4988/6370/58191/6755/6866/1524/94233/643/5029/2782/2867/185/339403/2914/8843/64106/2847/2833/6347/9290/9170/6469/187/6750/259296/259289/50835/2587/53829/8111/2787/6387/4544/4543/2922/10663/4889/2535/9283/1393/727/1909/5732/338398/117579/3579/6375/23566/2358/2916/7473/259293/1131/8322/6846/5179/27334/10681/27202/5021/6865/7471/2797/8811/56923/2832/2693/27199/2826/5727/6376/165140/27198/7201/89780/5443/8323/3627/2792/54429/3361/6346/553/257313/134/8321/3814/10800/2863/7481/1129/51554/51083/2785/2783/2784/2829/1233/222545/6366/1241/2861/728/7474/10022/183/7479/6373/57121/4922/5731/2865/7855/1132/1814/80835/3362/6357/552/2925/8698/9934/2151/6869/50840/2791/2147/1813/50865/7976/10886/2837/10803/146/2913/3357/351/11251/8477/84432/3352/8484/2828/3062/1907/148/6351/6863/6752/1903/84539/6753/3577/594857/2918/5368/6754/6915/8862/10911/301/5032/2642/56670/150/2853/29933/6751/5020/4935/887/4829/186/53637/60675/10563/5540/2864/1901/5733/256933/7200/5729/10850/624/2641/1392/2796/4852/4828/2786/680/50838/5473/4283/1910/6870/128674/11255/885/10874/83756/84634/147/6356/56477/387129/259286/3350/129521/1234/151/57007/1238/3356/84109/7472/9294/54331/4923/1128/283869/59345/4986/6608/6374/5539/259287/2852/50836/1230/846/3358/4886/2919/1908/51764/94235/259290/5196/3827/1604/5173/2357/55970/2778/6352/57105/1133/140/3269/6348/886/2862/152/1906/6364/80834/259292/5031/8620/2793/5030/5697/56413/3355/3351/6288/6372/50834/259285/719/6363/2917/1268/50831/2359/50839/347148/2846/5660/1815/1325/1232/4295/1902/551/154/50837/9002/1269/2915/59340/5724/4887/2790/718/623 342 Human_herpesvirus_8_type_P R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 106/5323 112/10654 2.8256532313958594e-25 6.116452456267653e-24 2.255946628466654e-24 6158/6138/6227/6206/1965/6234/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/6202/6169/6175/6218/6173/6167/116832/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/200916/6122/1968/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/9669/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 106 Human_herpesvirus_8_type_P R-HSA-202424 Downstream TCR signaling 95/5323 98/10654 3.1058031617012507e-25 6.522186639572627e-24 2.40559459343082e-24 5295/8454/5689/4790/5682/5291/7321/143471/5705/3115/5709/5695/4792/3113/5711/3117/5683/5699/5702/3127/7334/3551/5696/5691/7314/5718/8945/3635/5290/5700/122706/5707/8767/23198/23118/10892/8517/3126/5970/9861/5588/5698/5692/5713/5710/916/5719/6233/3932/3120/5170/3123/5706/3122/920/8915/5714/5688/5687/5708/7189/5704/7311/3125/5694/997/1147/5684/5720/6885/3119/84433/5690/5717/9491/6500/10197/919/7316/10213/7335/50852/7322/5715/5701/23291/915/5685/917/5686/5728/5716/5296/5693/5721 95 Human_herpesvirus_8_type_P R-HSA-5620912 Anchoring of the basal body to the plasma membrane 95/5323 98/10654 3.1058031617012507e-25 6.522186639572627e-24 2.40559459343082e-24 79867/7531/11190/203068/54801/85302/79441/5116/5048/22832/8655/9702/132320/7846/7840/11064/84902/5518/55835/23332/93323/1454/54806/91147/983/79959/10540/117177/57545/26005/54930/54820/23322/1453/9793/4218/11258/22981/8636/54903/80776/7532/55125/10382/121441/7277/9814/23354/146057/9738/1639/55722/4957/5566/7283/22919/27077/22994/4867/1069/5577/10383/5347/80184/22897/5108/261734/57787/10806/9657/1778/115106/22995/55559/10142/51134/95681/1781/80321/8766/79598/10121/347240/84131/3320/79600/10733/4751/80254/26123/9662/55142/8481/51259/55755 95 Human_herpesvirus_8_type_P R-HSA-375276 Peptide ligand-binding receptors 170/5323 201/10654 3.608027067111212e-25 7.465432475625699e-24 2.753494340690136e-24 729230/10316/2149/23620/7852/1237/4987/51289/2150/3060/3576/6360/4985/2920/3061/2921/1236/2831/5367/4988/6370/58191/6755/6866/1524/643/185/339403/64106/2847/2833/6347/187/6750/2587/6387/2922/10663/4889/9283/727/1909/117579/3579/6375/2358/6846/5179/27202/5021/6865/8811/56923/2832/2693/2826/6376/7201/5443/3627/6346/553/257313/3814/51554/51083/2829/1233/6366/2861/728/10022/183/6373/4922/6357/552/2925/2151/6869/2147/50865/10886/2837/10803/351/84432/8484/3062/1907/6351/6863/6752/84539/6753/3577/594857/5368/6754/8862/10911/301/6751/5020/887/4829/186/60675/10563/5540/256933/7200/10850/624/4852/4828/680/5473/4283/1910/6870/128674/885/10874/84634/6356/56477/387129/129521/1234/57007/1238/84109/4923/283869/4986/6374/5539/2852/1230/4886/2919/1908/5196/3827/5173/2357/6352/6348/886/2862/1906/6364/8620/5697/6288/6372/719/6363/2359/347148/5660/1325/1232/4295/551/9002/4887/718/623 170 Human_herpesvirus_8_type_P R-HSA-877300 Interferon gamma signaling 90/5323 92/10654 5.625192684408959e-25 1.147050160429479e-23 4.230694116573024e-24 80263/5777/960/5770/3107/817/9021/3383/55223/3662/3115/4684/567/6672/3113/3106/3459/3717/3117/11074/5371/3133/117854/3127/4938/4261/818/115362/7412/85363/9830/163351/3126/2634/115361/10475/10437/10612/3458/3661/5580/81603/10107/4940/5781/3660/8554/3135/3665/3120/10379/2633/3123/23650/2209/8638/7706/23087/3122/3394/3663/6772/8651/3659/2635/5771/816/10346/3716/3125/7726/79097/53840/3105/3460/815/6737/23321/4281/3119/4502/51127/3664/4939/388646/7341/55128/3134/80128/5724 90 Human_herpesvirus_8_type_P R-HSA-72613 Eukaryotic Translation Initiation 111/5323 119/10654 7.126027159167338e-25 1.4121577764716118e-23 5.208497241615269e-24 6158/6138/6227/6206/1965/6234/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/116832/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/1978/200916/6122/1968/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/8893/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/9669/6209/1964/11224/6165/6130/8890/6204/6228/6124/3646/6189/6135/6201/6161/8892/6133 111 Human_herpesvirus_8_type_P R-HSA-72737 Cap-dependent Translation Initiation 111/5323 119/10654 7.126027159167338e-25 1.4121577764716118e-23 5.208497241615269e-24 6158/6138/6227/6206/1965/6234/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/116832/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/1978/200916/6122/1968/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/8893/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/9669/6209/1964/11224/6165/6130/8890/6204/6228/6124/3646/6189/6135/6201/6161/8892/6133 111 Human_herpesvirus_8_type_P R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 85/5323 86/10654 7.586053712756561e-25 1.4621339142258193e-23 5.392825494432568e-24 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 85 Human_herpesvirus_8_type_P R-HSA-453276 Regulation of mitotic cell cycle 85/5323 86/10654 7.586053712756561e-25 1.4621339142258193e-23 5.392825494432568e-24 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 85 Human_herpesvirus_8_type_P R-HSA-69002 DNA Replication Pre-Initiation 84/5323 85/10654 1.5127966221326661e-24 2.876357901811704e-23 1.060894359475682e-23 5689/5682/143471/5705/5709/5422/1869/4174/5695/84515/4998/5711/10926/5683/990/5699/5702/55388/6117/5001/5558/5696/5691/7314/5718/6118/23594/5700/122706/5707/23198/5557/9861/5698/5692/5713/4175/5710/5719/6233/23649/4999/4172/5000/8318/54107/4173/5706/5714/51053/6119/5688/5687/5427/5708/81620/1870/5704/29935/23595/7311/5694/4176/56655/1017/5684/5720/8317/5690/5717/9491/10197/7316/10213/5426/4171/1871/5715/5701/5685/5686/5716/5693/5721 84 Human_herpesvirus_8_type_P R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 92/5323 95/10654 2.327666240242122e-24 4.366701866694221e-23 1.6105816932482334e-23 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/2935/6134/6155/6231/6142/23521/1981/6207/6233/6188/5976/200916/6122/6230/6194/2107/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/23708/9045/6187/6168/22916/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/4686/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 92 Human_herpesvirus_8_type_P R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 115/5323 125/10654 2.503527258156453e-24 4.6348195424028015e-23 1.709472213671927e-23 56955/4240/3270/9210/10272/2153/1511/7857/29106/91851/6696/51156/1435/265/11098/10130/2200/80341/375056/1114/720/10117/3956/3569/54972/2519/8720/7018/5340/10618/11167/813/5179/8074/4312/51246/348/4924/4313/3484/102/8614/336/6694/5069/4148/174/57104/721/2335/7466/116519/2266/51280/7076/2243/84141/3488/2147/8542/4221/351/4052/7184/56975/334/3912/338/64856/335/5611/197/3053/3895/5624/1000/54757/3481/8404/255738/3913/652/3817/57719/147111/2719/3487/3371/54587/401138/3486/7425/6383/3827/3490/5589/2621/3915/5768/1471/1462/10232/462/3698/5265/1758/258/11320/5954/3479/213/10970/5034/1356/718 115 Human_herpesvirus_8_type_P R-HSA-166166 MyD88-independent TLR4 cascade 95/5323 99/10654 3.920721362934998e-24 6.982854376771573e-23 2.5755038400092662e-23 8454/3725/9252/4790/7321/1848/4792/177/1432/929/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/1326/5601/6283/5606/8737/8767/1849/29110/5594/28512/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/1846/3665/351/330/79155/64127/5602/3656/7189/7311/9641/6416/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/7316/7335/4205/4793/3146/7322/329/466/23291/6288/2002/6285/5609/1385/5599/353376/148022 95 Human_herpesvirus_8_type_P R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic 95/5323 99/10654 3.920721362934998e-24 6.982854376771573e-23 2.5755038400092662e-23 11014/64837/11127/51807/53407/3798/5861/10381/285643/55738/10112/64147/7846/113457/51226/81027/11004/10749/81930/54732/60561/113220/79861/3797/29127/55605/377/1315/3796/124602/11316/55614/89953/56992/8729/23423/10376/1314/3835/147700/3833/378/9493/26286/26958/10959/3831/84364/22820/84617/55850/9585/10382/3832/7277/9554/23303/8775/26153/81876/9183/1062/11015/146909/347733/662/90990/23046/10383/24137/84790/84643/10945/51594/22920/7280/55582/9371/51014/23095/63908/6836/547/8774/10972/381/4905/3834/9276/55083/3799/375/221458/22818/372 95 Human_herpesvirus_8_type_P R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 95/5323 99/10654 3.920721362934998e-24 6.982854376771573e-23 2.5755038400092662e-23 8454/3725/9252/4790/7321/1848/4792/177/1432/929/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/1326/5601/6283/5606/8737/8767/1849/29110/5594/28512/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/1846/3665/351/330/79155/64127/5602/3656/7189/7311/9641/6416/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/7316/7335/4205/4793/3146/7322/329/466/23291/6288/2002/6285/5609/1385/5599/353376/148022 95 Human_herpesvirus_8_type_P R-HSA-69618 Mitotic Spindle Checkpoint 105/5323 112/10654 4.411691647184506e-24 7.75906268448575e-23 2.8617947132394236e-23 55839/11130/11065/6249/9735/7321/5526/8697/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/996/5515/79682/10403/25936/3619/64105/332/5528/51433/79902/3796/5519/81565/91687/119504/11243/7324/83540/64682/7514/54820/6396/64946/9793/140735/220134/4928/5903/246184/55055/80776/1783/401541/79172/79980/6232/8881/5501/54821/9183/1062/699/22919/5529/51143/10393/25906/5347/84643/1778/5516/5905/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/79023/55920/1781/4085/55166/79003/5527/701/57551 105 Human_herpesvirus_8_type_P R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 91/5323 94/10654 4.551292054183245e-24 7.905762864488674e-23 2.9159025116469656e-23 8454/3725/9252/4790/7321/1848/4792/177/1432/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/1326/5601/6283/5606/8737/8767/1849/29110/5594/28512/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5608/4791/1846/3665/351/330/7098/79155/64127/5602/3656/7189/7311/9641/6416/28511/5595/5516/1147/1845/6885/5604/10392/6500/7316/7335/4205/4793/3146/7322/329/466/23291/6288/2002/6285/5609/1385/5599/148022 91 Human_herpesvirus_8_type_P R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 94/5323 98/10654 7.598522348996593e-24 1.2880868608479768e-22 4.750883345663058e-23 8454/3725/9252/4790/1848/10333/4792/59307/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/11213/8767/1849/5594/4214/28512/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/653509/51295/79155/8651/64127/5602/3656/57162/695/7189/7311/6416/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/57161 94 Human_herpesvirus_8_type_P R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 94/5323 98/10654 7.598522348996593e-24 1.2880868608479768e-22 4.750883345663058e-23 8454/3725/9252/4790/1848/10333/4792/59307/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/11213/8767/1849/5594/4214/28512/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/653509/51295/79155/8651/64127/5602/3656/57162/695/7189/7311/6416/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/57161 94 Human_herpesvirus_8_type_P R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 90/5323 93/10654 8.89527817777031e-24 1.4724301642497444e-22 5.430801413796612e-23 8454/3725/9252/4790/1848/4792/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/6283/5606/8767/1849/5594/4214/28512/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/1846/3665/351/51295/79155/64127/5602/3656/57162/7189/7311/6416/51284/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/353376/57161/148022 90 Human_herpesvirus_8_type_P R-HSA-975155 MyD88 dependent cascade initiated on endosome 90/5323 93/10654 8.89527817777031e-24 1.4724301642497444e-22 5.430801413796612e-23 8454/3725/9252/4790/1848/4792/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/6283/5606/8767/1849/5594/4214/28512/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/1846/3665/351/51295/79155/64127/5602/3656/57162/7189/7311/6416/51284/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/353376/57161/148022 90 Human_herpesvirus_8_type_P R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 121/5323 134/10654 1.078072193187874e-23 1.7637762509480684e-22 6.505380553753022e-23 5295/8454/5689/3725/4893/5335/4790/5682/5291/7321/143471/5705/5530/5709/5695/4792/5711/5683/2534/5699/5702/2885/9846/3845/7334/3265/3551/5062/5696/5691/7314/5879/257397/5718/8945/5601/4773/5290/5700/122706/5707/5336/5594/4214/23198/23118/10892/8517/5970/9861/5588/5698/5692/5713/5710/10454/5719/6233/7410/7409/3702/2353/801/805/5170/6464/2205/4772/3937/4775/10451/5706/2206/6850/8915/5714/5688/5687/4067/5708/5602/695/7189/6654/5704/7311/5694/5058/6416/997/5595/1147/5684/5720/6885/84433/5690/5532/5717/9491/6500/10197/7316/10213/7335/10768/7322/5715/5701/23291/5685/5686/5534/5609/5716/5296/808/5599/5693/5721/2207 121 Human_herpesvirus_8_type_P R-HSA-9013694 Signaling by NOTCH4 81/5323 82/10654 1.1980245923059133e-23 1.9374949441085287e-22 7.146111603228256e-23 8454/5689/5682/182/23385/5705/5709/9978/5695/22938/5711/1387/4088/5683/5699/4853/5702/9794/388585/5696/5691/7314/5718/2648/5700/5707/55534/3280/84441/7534/102/5664/9861/8850/5698/5692/5713/5710/5719/6233/2324/5663/5706/10460/10046/5714/5688/5687/5708/59/4855/5704/83464/23493/7311/55851/51107/5694/4851/5684/5720/23462/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/2033/55294/5716/54567/3516/5693/5721 81 Human_herpesvirus_8_type_P R-HSA-2500257 Resolution of Sister Chromatid Cohesion 115/5323 126/10654 1.4625614588392835e-23 2.326869506152029e-22 8.582251648022673e-23 55839/11130/6249/9735/5526/51807/9212/10274/147841/348995/10381/57122/1780/23122/5048/57405/8655/23279/2491/7846/113457/1060/81027/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/79861/25936/55869/3619/64105/332/5528/983/79902/3796/5519/81565/91687/11243/10376/83540/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/55055/80776/1783/401541/10382/79172/7277/9133/79980/6232/23047/5885/891/5501/54821/9183/1062/699/347733/22919/8243/5529/51143/10383/5347/84790/84643/7280/1778/5516/5905/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23244/23421/79023/55920/10735/1781/4085/55166/79003/9126/5527/701/57551 115 Human_herpesvirus_8_type_P R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 93/5323 97/10654 1.4718648617450648e-23 2.326869506152029e-22 8.582251648022673e-23 8454/3725/9252/4790/1848/4792/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/6283/5606/8767/1849/5594/4214/28512/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/30849/5608/4791/1846/3665/351/8411/51295/79155/64127/5602/3656/57162/7189/7311/6416/51284/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/5289/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/353376/57161/148022 93 Human_herpesvirus_8_type_P R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 89/5323 92/10654 1.7377689234114863e-23 2.716712083599957e-22 1.0020117885869742e-22 8454/3725/9252/4790/1848/4792/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/6283/5606/8767/1849/5594/4214/28512/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/1846/351/51295/79155/64127/5602/3656/57162/7189/7311/6416/51284/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/353376/57161/148022 89 Human_herpesvirus_8_type_P R-HSA-72689 Formation of a pool of free 40S subunits 96/5323 101/10654 2.0832866701651448e-23 3.2210816977168775e-22 1.1880397089547907e-22 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/8663/23521/6207/6233/51386/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/8664/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 96 Human_herpesvirus_8_type_P R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 79/5323 80/10654 4.7540912320728366e-23 7.270659090789653e-22 2.681655580562825e-22 8454/5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 79 Human_herpesvirus_8_type_P R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 83/5323 85/10654 6.540287064368492e-23 9.585608228715072e-22 3.53548412580446e-22 8454/3725/9252/4790/1848/4792/177/1432/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/8767/1849/5594/4214/28512/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/81793/51295/79155/64127/5602/3656/57162/7189/7311/6416/28511/5595/5516/1147/1845/6885/5604/10392/6500/246330/4615/7100/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 83 Human_herpesvirus_8_type_P R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 83/5323 85/10654 6.540287064368492e-23 9.585608228715072e-22 3.53548412580446e-22 8454/3725/9252/4790/1848/4792/177/1432/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/8767/1849/5594/4214/28512/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/81793/51295/79155/64127/5602/3656/57162/7189/7311/6416/28511/5595/5516/1147/1845/6885/5604/10392/6500/246330/4615/7100/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 83 Human_herpesvirus_8_type_P R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 83/5323 85/10654 6.540287064368492e-23 9.585608228715072e-22 3.53548412580446e-22 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/91768/5934/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/1163/1019/5706/286826/4331/5714/5688/5687/91750/5708/1874/208/5704/55957/51343/7311/5694/1017/5684/994/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5715/5701/5685/5686/5716/1022/5693/5721/132660 83 Human_herpesvirus_8_type_P R-HSA-975871 MyD88 cascade initiated on plasma membrane 83/5323 85/10654 6.540287064368492e-23 9.585608228715072e-22 3.53548412580446e-22 8454/3725/9252/4790/1848/4792/177/1432/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/8767/1849/5594/4214/28512/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/81793/51295/79155/64127/5602/3656/57162/7189/7311/6416/28511/5595/5516/1147/1845/6885/5604/10392/6500/246330/4615/7100/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 83 Human_herpesvirus_8_type_P R-HSA-202403 TCR signaling 109/5323 119/10654 1.0284973302786044e-22 1.4918512821670065e-21 5.502432814187217e-22 5295/8454/5689/5335/4790/5682/5291/7321/143471/5705/5788/3115/5709/5695/4792/3113/5711/3117/5683/55824/5699/5702/26191/3127/7334/3551/5062/5696/5691/7314/5718/8945/3635/5290/5700/122706/5707/8767/23198/23118/10892/8517/3126/5970/9861/5588/5698/5692/5713/1445/5710/916/5719/6233/3702/3932/3120/5170/3937/3123/5706/3122/920/8915/5714/5795/5688/5687/5708/5063/7189/5704/7311/3125/5694/5058/997/1147/55740/5684/5720/6885/3119/84433/5690/5717/9491/6500/10197/919/7316/10213/7335/50852/7322/5715/5701/23291/915/5685/917/5686/7408/5728/7454/5716/5296/5693/5721 109 Human_herpesvirus_8_type_P R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 82/5323 84/10654 1.2883716578325325e-22 1.818010130707153e-21 6.705412744088778e-22 7124/10974/1052/84498/4790/79718/9441/892/5469/9612/1387/6907/84246/4023/55588/10499/23054/7040/85441/9282/23097/96764/51129/7471/3952/5465/10025/5970/6604/80205/9439/896/9370/1879/9412/9969/54797/5105/55090/1019/9440/6721/9862/1051/9442/1050/1024/9314/9968/5346/10001/23389/9443/9477/2167/51586/400569/6517/80306/8841/5468/29079/90390/6720/6837/688/9611/81857/2033/9967/7026/6256/51003/10498/948/112950/27332/8202/8648/1959/10891/219541 82 Human_herpesvirus_8_type_P R-HSA-156902 Peptide chain elongation 86/5323 89/10654 1.29211807441873e-22 1.818010130707153e-21 6.705412744088778e-22 6158/6138/6227/6206/6234/6191/6128/6132/6129/1915/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6166/1938/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 86 Human_herpesvirus_8_type_P R-HSA-192823 Viral mRNA Translation 86/5323 89/10654 1.29211807441873e-22 1.818010130707153e-21 6.705412744088778e-22 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/5611/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/2926/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 86 Human_herpesvirus_8_type_P R-HSA-156842 Eukaryotic Translation Elongation 89/5323 93/10654 2.061113352377826e-22 2.871273749302576e-21 1.0590191586474919e-21 6158/6138/6227/6206/6234/6191/6128/6132/6129/1915/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6166/1938/6136/6125/1937/6232/6160/1933/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/1936/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 89 Human_herpesvirus_8_type_P R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 85/5323 88/10654 2.5195994359118337e-22 3.46560487816228e-21 1.2782278120181079e-21 8454/7531/11190/203068/54801/79441/5116/5048/8655/6790/9702/7846/7840/11064/5518/55835/23332/93323/7314/8945/4659/1454/983/79959/10540/6233/54930/54820/1453/9793/4218/5500/11258/22981/8636/7532/84962/55125/10382/121441/7277/9133/9814/23354/891/9738/1639/55722/4957/5566/7283/22919/22994/79866/1069/5577/7311/10133/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/6500/1781/7316/80321/10121/84131/23291/3320/10733/4751/80254/9662/55142/8481/55755 85 Human_herpesvirus_8_type_P R-HSA-69202 Cyclin E associated events during G1/S transition 81/5323 83/10654 2.537009967666772e-22 3.46560487816228e-21 1.2782278120181079e-21 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/91768/5934/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/1163/1019/5706/286826/4331/5714/5688/5687/91750/5708/1874/208/5704/55957/7311/5694/1017/5684/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5715/5701/5685/5686/5716/1022/5693/5721/132660 81 Human_herpesvirus_8_type_P R-HSA-5607764 CLEC7A (Dectin-1) signaling 95/5323 101/10654 3.4341804543047338e-22 4.646049903083423e-21 1.7136143360042856e-21 8454/5689/4790/5682/7321/29108/143471/5705/5530/5709/5695/4792/5711/5683/5699/5702/64170/7334/3551/5696/5691/7314/257397/5718/8945/4773/5700/122706/5707/5336/23198/23118/10892/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/801/4791/805/5170/4772/4775/5706/64581/6850/8915/5714/5688/5687/5708/7189/5704/7311/5971/5694/997/1147/5684/5720/6885/84433/5690/3553/5532/5717/9491/6500/10197/7316/10213/7335/10768/7322/5715/5701/23291/5685/5686/5534/5716/808/5693/5721 95 Human_herpesvirus_8_type_P R-HSA-195253 Degradation of beta-catenin by the destruction complex 80/5323 82/10654 4.993866502562118e-22 6.566701092621402e-21 2.4220129717295862e-21 8454/5689/5682/5526/1452/143471/5705/5709/9978/5695/5711/5683/324/5699/8312/5702/6932/5518/5696/5691/7314/5515/5718/51176/8945/5700/122706/5707/23198/5528/7091/83439/9861/5519/2932/5698/5692/5713/5710/5719/6233/7089/7090/10023/5706/23401/5714/6934/5688/5687/5708/5529/7088/5704/7311/5694/5516/5684/5720/1487/1499/5525/139285/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/3065/5527/1488/5716/5693/5721 80 Human_herpesvirus_8_type_P R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 80/5323 82/10654 4.993866502562118e-22 6.566701092621402e-21 2.4220129717295862e-21 114791/10844/440145/7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/1454/983/79959/80097/10540/85378/54930/54820/1453/27229/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/728642/9738/1639/55722/4957/5566/7283/22919/984/10426/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 80 Human_herpesvirus_8_type_P R-HSA-380287 Centrosome maturation 80/5323 82/10654 4.993866502562118e-22 6.566701092621402e-21 2.4220129717295862e-21 114791/10844/440145/7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/1454/983/79959/80097/10540/85378/54930/54820/1453/27229/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/728642/9738/1639/55722/4957/5566/7283/22919/984/10426/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 80 Human_herpesvirus_8_type_P R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 100/5323 108/10654 7.373793245633998e-22 9.606413978339848e-21 3.5431579630580524e-21 5295/3605/7124/2308/1052/7291/356/3593/246/9021/6624/3082/5743/3091/10538/3383/6097/6657/3576/3662/3688/4985/7133/3606/4609/4988/3717/2162/6347/7040/3312/3569/4692/3596/7412/3911/4582/4312/6778/332/4313/3565/3934/3976/5443/3718/149233/598/2247/2335/595/7157/2353/604/7076/51561/3570/7297/3566/7184/3684/4318/3726/58480/301/6774/6772/8651/1901/3552/79923/3716/240/6356/5008/3586/596/2208/2309/3561/207/5292/5451/7422/3553/2625/4314/1026/3320/4843/6288/948/6935/3687/7431/3929/3162/1278/4170/3689 100 Human_herpesvirus_8_type_P R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 75/5323 76/10654 7.463836550770173e-22 9.634511951315258e-21 3.5535214094927046e-21 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 75 Human_herpesvirus_8_type_P R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic 166/5323 202/10654 7.648342314834615e-22 9.782925124520275e-21 3.608261015515278e-21 6811/400/11014/64837/11311/8674/11127/51807/53407/3798/5861/10381/1780/5048/9570/8655/84516/832/285643/55738/10112/636/64147/7846/113457/2590/51226/9382/81027/11004/10228/10749/6293/8675/2800/339122/81930/10652/54732/7110/51272/51164/60561/113220/79861/3797/10618/29127/55275/55605/23299/377/10466/8398/9827/1315/22836/3796/5870/79571/124602/11316/55614/89953/56992/91949/8729/4074/23423/10376/2803/1314/10540/3835/147700/3833/8677/10139/378/9493/26286/26958/140735/10959/1523/3831/84364/22820/51542/84617/22796/11258/1783/55850/9585/10382/93661/55860/830/3832/7277/10671/9554/23303/1639/8775/26153/81876/9183/1062/11015/146909/347733/662/90990/51143/9648/23046/10383/24137/84790/84643/10945/5049/90196/57589/51594/22920/7280/829/1778/55582/5321/9371/25839/51014/23095/5050/84316/83548/63908/1781/738/10121/10226/9341/6836/9342/9527/57511/547/51560/8774/143187/10972/381/4905/3834/9276/55083/3799/375/84342/221458/22818/372 166 Human_herpesvirus_8_type_P R-HSA-73894 DNA Repair 251/5323 334/10654 1.0232940497953568e-21 1.2970943496054657e-20 4.784105894254253e-21 2237/4436/221120/83990/151987/5892/9156/2074/1763/7486/27343/4913/56852/10445/5982/8505/11200/472/6613/7507/80198/3981/5431/5435/2140/9978/5433/85015/10980/64421/4683/57654/2965/25898/165918/84126/5439/10987/8900/8924/57599/2067/672/2967/6612/6117/7334/10973/10714/55666/54386/348654/91603/83695/4437/55183/7314/51514/7014/6118/2176/25/5888/322/328/83444/51588/79068/7518/51720/63967/404672/9557/5531/9636/3150/86/5438/3978/11201/116028/2070/890/197342/9031/1643/7517/9656/84464/51455/29844/2177/5985/10920/29089/2068/7157/5984/4595/4255/54891/6233/7158/6047/93973/55247/8607/7874/5884/5810/5424/5886/57697/8451/8554/10450/8467/80010/3838/5434/7516/5436/2956/7515/54107/7013/4292/7706/51567/580/11073/5591/8450/5423/4331/5425/641/5111/2966/6119/83932/3364/22976/10524/5427/144715/1161/5889/55775/1642/5429/142/125476/1111/2071/9682/55215/10721/1069/7329/9246/79728/51426/2873/146956/7311/4968/23030/3980/60/5536/8533/5983/2175/10038/2547/79840/5432/51138/7528/56655/9318/11284/51750/1017/54962/25913/6917/5440/5893/902/5883/27339/5430/10111/57804/7320/7520/675/51548/545/5441/7336/2072/29086/54778/7316/6996/64708/8314/5426/9100/10635/7415/5395/283899/7341/4798/5437/79913/10401/9937/54617/65057/2033/8914/7398/23514/2968/5932/8930/2138/9025/2189/55120/2187/79184/56949/7156/5890/5887/9716/2073/5599/5981/1022/2139/8178/50813/7508/7374 251 Human_herpesvirus_8_type_P R-HSA-4420097 VEGFA-VEGFR2 Pathway 93/5323 99/10654 1.2385361502287012e-21 1.555911038724806e-20 5.73870603442434e-21 5295/4893/857/5335/71/5579/5291/5578/1432/2534/9475/3690/5603/2475/6093/8440/9564/3845/3265/3071/8877/5062/5829/5879/26999/5290/5567/10006/57761/5921/1500/9261/6714/10810/10000/3728/7410/5580/7409/23191/3685/3791/1535/5600/6300/801/10787/253260/805/5170/4688/5590/653361/6461/5747/5568/3315/10451/1793/10152/64223/5566/1003/10163/55845/5063/998/208/79109/2185/387/60/5058/63916/25759/558/1495/1499/207/7422/10458/9047/55615/10768/8936/3320/4846/1398/4689/9844/5296/808/1536 93 Human_herpesvirus_8_type_P R-HSA-76002 Platelet activation, signaling and aggregation 205/5323 262/10654 1.3770280337207998e-21 1.702731956682518e-20 6.2802293393519735e-21 5295/2788/2149/5777/5579/2153/5770/5291/7042/64805/2770/5175/3959/5578/5582/5908/3082/388/5583/29106/2769/7423/5028/1432/3920/374354/2244/7114/3309/2534/3690/408/2162/2768/2782/87/2776/5894/10487/2885/51206/7040/9564/5874/54863/51266/350/7043/2773/967/5879/5054/2787/5099/1072/5290/7018/6678/5340/10630/5336/813/7094/5594/10681/7414/10490/83706/7044/7534/6810/7123/2792/6714/6694/3671/7273/22927/1191/3273/27154/226/5588/5880/2335/5294/1/2785/2783/2784/1445/8525/5478/2771/94121/22915/7410/5580/2266/7409/3932/7076/2243/801/5781/2151/2791/2147/805/5170/5590/351/6464/135228/5747/51097/3937/7424/2316/3674/5552/409/6915/2157/7277/10451/334/1277/10447/150/335/308/6850/78991/8503/197/4067/81/9948/998/3481/2786/6654/5473/8407/7450/387/29789/10916/5595/139322/151/5321/54331/5005/59345/1606/207/7422/5004/51764/94235/5196/3827/54518/1950/55970/2621/5216/2767/5768/346562/710/152/6647/2793/5265/7078/55664/391/5345/54676/2/1398/948/88/1675/5906/3479/5155/5296/5581/51368/808/213/5660/9630/7057/1278/9002/2207/5627/6814/2790/10672 205 Human_herpesvirus_8_type_P R-HSA-194138 Signaling by VEGF 99/5323 107/10654 1.3796122463525732e-21 1.702731956682518e-20 6.2802293393519735e-21 5295/4893/857/5335/71/5579/5291/5578/8829/7423/1432/2534/9475/3690/5603/2475/6093/8440/9564/3845/3265/3071/8877/5062/5829/5879/26999/5290/5567/10006/57761/5921/1500/9261/6714/2321/10810/10000/3728/7410/5580/2324/7409/23191/3685/3791/1535/5600/6300/801/10787/253260/805/5170/4688/5590/653361/6461/5747/7424/5568/3315/10451/1793/10152/64223/5566/1003/10163/55845/5063/998/208/79109/2185/387/60/5058/63916/25759/558/1495/1499/207/7422/10458/9047/55615/10768/8936/3320/4846/1398/4689/9844/5228/5296/808/1536 99 Human_herpesvirus_8_type_P R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 74/5323 75/10654 1.4847486813299837e-21 1.8165577344619888e-20 6.70005583428542e-21 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 74 Human_herpesvirus_8_type_P R-HSA-162909 Host Interactions of HIV factors 115/5323 129/10654 1.8629351843202017e-21 2.2596119002918306e-20 8.334183719327218e-21 23165/5689/162/5682/1174/348995/143471/57122/5705/23511/5709/9978/5695/292/567/23279/5711/23225/5683/2534/5699/5702/3836/163/9972/8021/904/5062/55746/5696/5691/7314/5879/5718/8945/161/5700/122706/5707/23198/10762/926/9861/79902/11168/9883/5698/5692/5713/5710/5478/5719/6233/7514/1025/3932/6396/129401/1175/940/60489/1173/4928/5903/55706/7175/4869/5706/160/293/920/5714/4927/5688/5687/5708/5901/8086/5704/7311/5694/1104/5905/3837/164/5684/8065/5720/9631/3159/5690/5717/9491/6500/79023/23636/10197/919/7316/10213/53371/3055/9688/5715/5701/5685/8815/5686/5716/9844/375/5693/5721/8480/291 115 Human_herpesvirus_8_type_P R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 89/5323 94/10654 1.976790708409322e-21 2.3772175442153126e-20 8.767951590155609e-21 114791/10844/440145/7531/11190/203068/54801/51807/79441/10381/5116/5048/8655/9702/7846/7840/113457/11064/81027/5518/55835/29922/23332/93323/79861/1454/983/79959/80097/10376/10540/85378/54930/54820/1453/27229/9793/84617/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/9738/1639/55722/4957/5566/7283/347733/22919/10426/22994/1069/5577/10383/5347/84790/80184/22897/5108/7280/10806/1778/115106/4926/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 89 Human_herpesvirus_8_type_P R-HSA-8878166 Transcriptional regulation by RUNX2 109/5323 121/10654 2.942733326670134e-21 3.5088354157837955e-20 1.2941726405427085e-20 8454/8493/5689/7291/5682/5925/143471/5705/5709/9978/5695/9759/10413/4089/5711/650/5683/1749/5699/5702/121340/5696/5691/7314/5718/25/6662/5700/122706/5707/5594/3280/23198/10013/2737/865/11059/983/6714/2099/9861/2932/6502/5698/10000/5692/5713/595/5710/5719/6233/7525/10432/4091/117581/1019/3958/5706/3678/1277/891/5714/6772/2736/5688/5687/4322/2908/5708/4488/208/5704/23493/7311/367/860/1750/5694/5595/57154/5684/8841/5720/23462/10273/207/5690/5717/9491/6500/4086/10197/7316/10213/4094/1026/5715/5701/5685/5686/55294/23314/861/5716/25937/581/5693/5721/10891 109 Human_herpesvirus_8_type_P R-HSA-72764 Eukaryotic Translation Termination 88/5323 93/10654 3.778249799433455e-21 4.4551847372125613e-20 1.6432170541621164e-20 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/51504/6147/6222/2935/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/2107/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/23708/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 88 Human_herpesvirus_8_type_P R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 77/5323 79/10654 3.799731119157835e-21 4.4551847372125613e-20 1.6432170541621164e-20 2074/5982/7507/5431/5435/9978/5433/10980/57654/2965/5439/10987/2067/2967/6117/10714/91603/7314/6118/404672/3150/5438/3978/5985/10920/2068/5984/6233/7874/5424/8451/10450/5434/5436/7515/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/2071/51426/2873/7311/3980/8533/5983/5432/51138/56655/9318/6917/5440/902/27339/5430/57804/5441/2072/7316/64708/5426/5437/2033/2968/56949/9716/2073/5981/1022/8178/50813 77 Human_herpesvirus_8_type_P R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72/5323 73/10654 5.8705928624516304e-21 6.826383601214417e-20 2.5177923281328008e-20 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/5716/701/5693/5721 72 Human_herpesvirus_8_type_P R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 80/5323 83/10654 7.051004076643877e-21 8.131772734293389e-20 2.9992623035249626e-20 8454/5689/4893/4790/5579/5682/143471/5705/5530/5709/5695/4792/5711/5683/5699/5702/4794/3845/3265/3551/5696/5691/7314/5718/8945/4773/5966/5700/122706/5707/23198/10892/8517/5970/9861/5698/5692/5713/5710/2280/5478/5719/6233/801/805/4772/4775/5706/8915/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/84433/5690/5532/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5534/5716/808/5693/5721 80 Human_herpesvirus_8_type_P R-HSA-8878159 Transcriptional regulation by RUNX3 90/5323 96/10654 8.436405292979009e-21 9.650424591236964e-20 3.559390508719428e-20 5689/6046/5682/182/5705/6097/6696/5709/5695/9759/10413/4609/4089/22938/5711/1387/4088/5683/5699/5702/9794/6932/7040/3845/5696/5691/7314/5718/8463/51176/2648/5700/5707/55534/3280/84441/865/83439/6714/9861/8850/5698/5692/5713/595/5710/7157/5719/6233/7004/1029/864/5706/10046/5714/6934/5688/5687/5708/5704/7311/5694/4851/3676/57154/5684/5720/2309/1499/10018/5690/5717/9491/10197/64750/7316/10213/1026/5715/5701/5685/5686/2033/861/5716/25937/3516/5693/5721/4193 90 Human_herpesvirus_8_type_P R-HSA-5663220 RHO GTPases Activate Formins 122/5323 140/10654 9.897806673332244e-21 1.1230817733369733e-19 4.1422909082791147e-20 55839/11130/71/6249/9735/5526/51807/9212/388/147841/348995/10381/57122/1780/23122/3688/5048/57405/8655/23279/2491/7846/113457/1060/81027/11004/1855/9184/5518/23332/25909/10726/81930/55746/5879/5515/79682/10403/79861/25936/1856/389/3619/64105/332/5528/6714/79902/3796/5519/81565/91687/11243/10376/83540/1857/7514/54820/29984/1729/6396/64946/9793/140735/220134/84617/4928/5903/55055/80776/1783/401541/10382/79172/7277/79980/6232/5501/54821/9183/1062/699/347733/752/22919/5529/51143/998/286205/10383/5347/387/60/84790/84643/7280/1778/5516/5905/54908/55143/5525/1058/991/79019/348235/80152/1063/6722/8379/23421/79023/55920/1781/4085/5216/55166/79003/5527/701/23380/57551 122 Human_herpesvirus_8_type_P R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 71/5323 72/10654 1.166852744104481e-20 1.2927258353976416e-19 4.7679933928181456e-20 5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 71 Human_herpesvirus_8_type_P R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 71/5323 72/10654 1.166852744104481e-20 1.2927258353976416e-19 4.7679933928181456e-20 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 71 Human_herpesvirus_8_type_P R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 71/5323 72/10654 1.166852744104481e-20 1.2927258353976416e-19 4.7679933928181456e-20 5689/9134/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/990/5699/5702/8900/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/898/890/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/1017/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 71 Human_herpesvirus_8_type_P R-HSA-6802957 Oncogenic MAPK signaling 70/5323 71/10654 2.3186061874960507e-20 2.52889837659453e-19 9.327399840355391e-20 4893/71/817/5908/55109/54845/8546/22866/5605/5037/3717/10827/2244/3690/408/4296/5894/8826/1185/4140/3845/3265/4763/818/8805/55750/8844/7094/5594/7414/10533/23164/57085/6714/9061/2335/1445/2266/2243/369/801/57670/805/283455/3674/409/673/8315/816/56829/7450/60/9444/7529/5595/4000/27044/815/22906/8087/5604/10018/10142/54518/80853/10256/5906/808/9715/5245 70 Human_herpesvirus_8_type_P R-HSA-68949 Orc1 removal from chromatin 70/5323 71/10654 2.3186061874960507e-20 2.52889837659453e-19 9.327399840355391e-20 8454/5689/5682/143471/5705/5709/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/890/9861/6502/5698/5692/5713/4175/5710/5719/6233/4999/4172/5000/4173/5706/5714/5688/5687/5708/81620/5704/23595/7311/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 70 Human_herpesvirus_8_type_P R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 150/5323 182/10654 4.281656750999566e-20 4.634070037427992e-19 1.7091957718565072e-19 1912/23165/7068/7486/9112/6045/9212/80012/10274/348995/6613/57122/7181/23511/28996/4792/3190/9759/9612/8856/1911/9994/6790/6672/23279/1387/1789/23225/23512/165918/57332/7022/7067/7428/1107/5371/8924/4152/672/115426/9972/10499/6612/5914/8021/6117/11315/55746/7421/4286/10062/7150/6670/3622/1788/51564/51588/7518/3619/7153/2516/8517/332/10762/5465/1655/5970/2099/79902/2494/9656/9883/84733/3066/7157/668/7158/10155/9063/7155/6396/129401/7703/9189/4791/6015/8554/7020/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/493861/5111/4927/10521/1616/2908/8243/142/1069/8086/7329/367/25942/9641/648/23468/5905/5893/1487/55143/9631/5468/7021/8204/3090/79023/23636/10735/3183/4306/53371/6996/23137/9688/7341/10401/2033/9126/3065/23314/6256/5987/7376/6294/8648/6304/8480/10891/7508/4193 150 Human_herpesvirus_8_type_P R-HSA-2219528 PI3K/AKT Signaling in Cancer 93/5323 101/10654 5.812849160860249e-20 6.243266236130055e-19 2.302719675615993e-19 5295/2308/374/2250/5291/3082/941/2064/145957/2534/9965/2264/9542/2885/2475/8660/2252/5879/1839/5290/3667/8823/2065/3815/2069/84335/8074/7249/2260/2249/6714/2099/2248/2932/2247/5880/10000/7409/2246/2251/3932/2931/118788/5781/940/253260/5170/572/4303/930/6199/2263/4233/64223/8503/5159/3084/208/10718/79109/5293/1956/2549/1147/685/2309/842/207/1027/8817/2100/2254/152831/1950/1026/55615/50852/26281/10818/2261/2255/3164/391/5728/2066/27006/942/1385/5155/4254/5296/5156/4193 93 Human_herpesvirus_8_type_P R-HSA-983705 Signaling by the B Cell Receptor (BCR) 101/5323 112/10654 7.217695727364584e-20 7.693407491213613e-19 2.8375789422573683e-19 5295/8454/5689/5777/4893/4790/5579/5682/143471/5705/5530/5709/5695/4792/5711/5683/2534/5699/5702/30011/2885/4794/3845/3265/3551/973/933/5696/5691/7314/5718/8945/4773/5966/5700/122706/5707/5336/23198/10892/8517/5970/9861/5698/5692/5713/5710/2280/5478/5719/6233/7409/118788/801/805/4772/4775/930/5706/6850/8915/5714/5688/5687/4067/29760/5708/695/6654/5704/7311/5293/27071/5694/1147/5684/5720/6885/640/84433/5690/5532/5717/9491/6500/10197/7316/10213/10768/4793/5715/5701/23291/5685/5686/5534/974/5716/808/5693/5721 101 Human_herpesvirus_8_type_P R-HSA-141424 Amplification of signal from the kinetochores 89/5323 96/10654 1.1172619404270758e-19 1.1731250374484296e-18 4.326866744937537e-19 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/79902/3796/5519/81565/91687/11243/83540/7514/54820/6396/64946/9793/140735/220134/4928/5903/55055/80776/1783/401541/79172/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/5905/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/79023/55920/1781/4085/55166/79003/5527/701/57551 89 Human_herpesvirus_8_type_P R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 89/5323 96/10654 1.1172619404270758e-19 1.1731250374484296e-18 4.326866744937537e-19 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/79902/3796/5519/81565/91687/11243/83540/7514/54820/6396/64946/9793/140735/220134/4928/5903/55055/80776/1783/401541/79172/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/5905/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/79023/55920/1781/4085/55166/79003/5527/701/57551 89 Human_herpesvirus_8_type_P R-HSA-68867 Assembly of the pre-replicative complex 67/5323 68/10654 1.8159242463598267e-19 1.8925966034283526e-18 6.980511917780856e-19 5689/5682/143471/5705/5709/1869/4174/5695/84515/4998/5711/5683/990/5699/5702/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/9861/5698/5692/5713/4175/5710/5719/6233/4999/4172/5000/4173/5706/5714/51053/5688/5687/5708/81620/1870/5704/23595/7311/5694/4176/5684/5720/5690/5717/9491/10197/7316/10213/4171/1871/5715/5701/5685/5686/5716/5693/5721 67 Human_herpesvirus_8_type_P R-HSA-8854518 AURKA Activation by TPX2 71/5323 73/10654 2.174952049811032e-19 2.2501158338853837e-18 8.299159137436833e-19 7531/11190/203068/54801/79441/5116/5048/8655/6790/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/22974/3161/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 71 Human_herpesvirus_8_type_P R-HSA-1169091 Activation of NF-kappaB in B cells 66/5323 67/10654 3.6040630603971e-19 3.648141529481094e-18 1.3455532667745329e-18 8454/5689/4790/5579/5682/143471/5705/5709/5695/4792/5711/5683/5699/5702/4794/3551/5696/5691/7314/5718/8945/5966/5700/122706/5707/23198/10892/8517/5970/9861/5698/5692/5713/5710/5719/6233/5706/8915/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/84433/5690/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5716/5693/5721 66 Human_herpesvirus_8_type_P R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 66/5323 67/10654 3.6040630603971e-19 3.648141529481094e-18 1.3455532667745329e-18 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 66 Human_herpesvirus_8_type_P R-HSA-6802952 Signaling by BRAF and RAF fusions 66/5323 67/10654 3.6040630603971e-19 3.648141529481094e-18 1.3455532667745329e-18 4893/71/817/5908/55109/54845/8546/22866/5605/5037/3717/10827/2244/3690/408/5894/8826/1185/4140/3845/3265/818/8805/55750/8844/7094/5594/7414/10533/23164/57085/6714/9061/2335/1445/2266/2243/369/801/57670/805/283455/3674/409/673/816/56829/7450/60/9444/7529/5595/4000/27044/815/22906/8087/5604/10018/10142/54518/80853/10256/5906/808/9715 66 Human_herpesvirus_8_type_P R-HSA-3371556 Cellular response to heat stress 83/5323 89/10654 7.218481465117876e-19 7.203122993915497e-18 2.656746071148274e-18 23165/6782/573/7531/1915/817/9530/348995/472/57122/3313/23511/3305/23279/91582/1387/259217/23225/3309/9531/2475/3306/27000/9972/23411/8021/6117/3312/55746/51182/818/3303/6118/5594/3308/84335/10049/10013/3337/10762/9261/79902/9883/2932/6396/129401/3297/57521/4928/5903/55706/7175/1410/4927/64223/6119/57805/3310/7266/816/8086/3326/3304/10728/5595/815/9631/116835/545/79023/23636/10808/53371/9532/9688/7415/3320/2033/6767/22824/9529/2288/8480 83 Human_herpesvirus_8_type_P R-HSA-5687128 MAPK6/MAPK4 signaling 83/5323 89/10654 7.218481465117876e-19 7.203122993915497e-18 2.656746071148274e-18 2308/5689/2118/3725/5682/27327/143471/5705/5709/5695/4609/5711/5683/5699/5702/192669/8997/4343/5062/5696/5691/7314/5879/5718/5700/122706/5707/5567/23198/3337/983/9861/5698/5692/5713/5710/8555/896/5719/6233/7514/26523/5568/3315/5706/5597/5714/5566/5688/5687/5708/5063/998/5704/7311/5694/5058/27161/5684/5720/2309/10642/5690/57690/5717/9491/10197/192670/5596/8550/7316/10213/5715/5701/5685/5686/8556/23112/5716/5896/8202/5693/5721 83 Human_herpesvirus_8_type_P R-HSA-2408557 Selenocysteine synthesis 86/5323 93/10654 7.305420556715094e-19 7.238539945984604e-18 2.6698089951523662e-18 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/51091/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/79048/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 86 Human_herpesvirus_8_type_P R-HSA-72202 Transport of Mature Transcript to Cytoplasm 79/5323 84/10654 1.244919383395643e-18 1.2248962045018668e-17 4.517815649716983e-18 23165/8683/6431/84271/199746/348995/57122/23511/81608/65109/23279/23225/9877/9972/8021/55746/7919/53981/6432/8563/6430/56001/80145/10762/22794/9785/11338/29107/4116/79902/9883/51213/10250/26097/51362/1977/57187/6396/129401/79228/2733/84324/4928/5903/55706/7175/7884/6428/10212/55110/84321/6429/4927/10898/10569/9295/10482/51692/8086/9939/6426/22916/10921/9631/29894/79023/23636/4686/8189/53371/7307/9688/9984/10189/9775/84248/6427/8480/55339 79 Human_herpesvirus_8_type_P R-HSA-380259 Loss of Nlp from mitotic centrosomes 68/5323 70/10654 1.6353890191306142e-18 1.5868912758046717e-17 5.8529712263622e-18 7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 68 Human_herpesvirus_8_type_P R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 68/5323 70/10654 1.6353890191306142e-18 1.5868912758046717e-17 5.8529712263622e-18 7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 68 Human_herpesvirus_8_type_P R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 58/5323 58/10654 2.841115002164664e-18 2.664965872030455e-17 9.82926102503284e-18 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/57534/388585/28514/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/102/5664/8850/3066/6233/5663/142678/10046/1024/10014/26508/9148/83464/23493/7311/55851/51107/4851/8841/23462/6500/7316/9611/54492/2033/55294/3065/54567/3516 58 Human_herpesvirus_8_type_P R-HSA-2644603 Signaling by NOTCH1 in Cancer 58/5323 58/10654 2.841115002164664e-18 2.664965872030455e-17 9.82926102503284e-18 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/57534/388585/28514/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/102/5664/8850/3066/6233/5663/142678/10046/1024/10014/26508/9148/83464/23493/7311/55851/51107/4851/8841/23462/6500/7316/9611/54492/2033/55294/3065/54567/3516 58 Human_herpesvirus_8_type_P R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 58/5323 58/10654 2.841115002164664e-18 2.664965872030455e-17 9.82926102503284e-18 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/57534/388585/28514/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/102/5664/8850/3066/6233/5663/142678/10046/1024/10014/26508/9148/83464/23493/7311/55851/51107/4851/8841/23462/6500/7316/9611/54492/2033/55294/3065/54567/3516 58 Human_herpesvirus_8_type_P R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 58/5323 58/10654 2.841115002164664e-18 2.664965872030455e-17 9.82926102503284e-18 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/57534/388585/28514/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/102/5664/8850/3066/6233/5663/142678/10046/1024/10014/26508/9148/83464/23493/7311/55851/51107/4851/8841/23462/6500/7316/9611/54492/2033/55294/3065/54567/3516 58 Human_herpesvirus_8_type_P R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 58/5323 58/10654 2.841115002164664e-18 2.664965872030455e-17 9.82926102503284e-18 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/57534/388585/28514/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/102/5664/8850/3066/6233/5663/142678/10046/1024/10014/26508/9148/83464/23493/7311/55851/51107/4851/8841/23462/6500/7316/9611/54492/2033/55294/3065/54567/3516 58 Human_herpesvirus_8_type_P R-HSA-909733 Interferon alpha/beta signaling 67/5323 69/10654 3.2007531590342974e-18 2.981066995731477e-17 1.0995144794041958e-17 3443/5777/5770/3107/9021/11274/3662/3106/4599/684/3133/3429/91543/4938/5696/3445/10410/9636/2634/3444/103/3434/3433/3451/3448/3661/3439/10581/3452/4940/3437/6773/7297/5781/3430/3660/3446/3135/3665/10379/3455/4600/8638/3394/3663/6772/8651/3659/25939/3440/3454/3716/3456/3105/3441/51447/54739/2537/3449/8519/3664/6041/1958/4939/6059/3669/3134 67 Human_herpesvirus_8_type_P R-HSA-9006936 Signaling by TGF-beta family members 92/5323 102/10654 3.2204846009323702e-18 2.981066995731477e-17 1.0995144794041958e-17 10272/892/7321/4738/9372/91851/130399/8239/9612/56937/4609/4089/22938/23327/4088/650/5499/1030/9110/7040/10589/904/7314/5054/7027/11167/6497/51592/50848/7323/91/93/6667/4092/11171/7050/7046/92/94/5494/2280/9958/9040/6233/3625/7514/1025/8928/57530/2658/4091/5500/4090/4221/4093/5590/9765/269/3726/5501/3624/1024/60436/23645/8812/1874/142/905/4087/7048/7311/387/57154/51377/10273/50855/4086/658/64750/659/54778/7316/1875/9611/5933/867/3065/6498/657/56288/25937/23439 92 Human_herpesvirus_8_type_P R-HSA-2990846 SUMOylation 151/5323 188/10654 3.761316143289863e-18 3.4589358258881285e-17 1.2757680486012401e-17 1912/23165/7068/7486/9112/6045/9212/80012/10274/348995/6613/57122/7181/23511/28996/4792/3190/9759/9612/8856/1911/9994/6790/6672/23279/1387/1789/23225/23512/165918/57332/7022/7067/7428/1107/5371/8924/4152/672/115426/9972/10499/6612/5914/8021/6117/11315/55746/7421/4286/10062/7150/6670/3622/1788/51564/51588/7518/3619/7153/2516/8517/332/10762/5465/1655/5970/2099/79902/2494/9656/9883/84733/3066/7157/668/7158/10155/9063/7155/6396/129401/7703/9189/4791/6015/8554/7020/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/493861/5111/4927/10521/1616/2908/8243/142/1069/8086/7329/367/25942/9641/648/23468/5905/5893/29843/1487/55143/9631/5468/7021/8204/3090/79023/23636/10735/3183/4306/53371/6996/23137/9688/7341/10401/2033/9126/3065/23314/6256/5987/7376/6294/8648/6304/8480/10891/7508/4193 151 Human_herpesvirus_8_type_P R-HSA-2871837 FCERI mediated NF-kB activation 77/5323 82/10654 4.476362716259126e-18 4.0897677544003834e-17 1.5084393842212916e-17 8454/5689/4790/5682/7321/143471/5705/5709/5695/4792/5711/5683/5699/5702/7334/3551/5696/5691/7314/257397/5718/8945/5700/122706/5707/23198/23118/10892/8517/5970/9861/5588/5698/5692/5713/5710/10454/5719/6233/5170/2205/5706/2206/8915/5714/5688/5687/4067/5708/7189/5704/7311/5694/997/1147/5684/5720/6885/84433/5690/5717/9491/6500/10197/7316/10213/7335/7322/5715/5701/23291/5685/5686/5716/5693/5721/2207 77 Human_herpesvirus_8_type_P R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 62/5323 63/10654 5.5742572028992425e-18 5.0599870222446675e-17 1.8662878105462322e-17 5689/11065/5682/7321/8697/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/5707/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 62 Human_herpesvirus_8_type_P R-HSA-6807878 COPI-mediated anterograde transport 91/5323 101/10654 5.8663615218650874e-18 5.291006834143704e-17 1.9514954320374415e-17 6811/6711/11014/51807/5861/10381/1780/9570/8655/84516/832/55738/7846/113457/51226/9382/3630/81027/6709/10652/54732/51272/51164/79861/2801/377/10466/1315/8615/11316/91949/8729/23423/10376/1314/10540/378/26286/26958/140735/10959/84364/22820/84617/22796/11258/6712/1783/10382/93661/55860/830/7277/10671/966/1639/10282/8775/81876/11015/347733/51143/10383/84790/10945/7280/829/1778/25839/51014/83548/63908/1604/1781/57731/10121/2804/9527/57511/8774/10972/381/4905/9276/287/375/84342/64689/288/22818/372 91 Human_herpesvirus_8_type_P R-HSA-69615 G1/S DNA Damage Checkpoints 66/5323 68/10654 6.2612643923630244e-18 5.611209554175016e-17 2.0695966110861356e-17 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/993/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/1111/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 66 Human_herpesvirus_8_type_P R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 73/5323 77/10654 7.188971925219504e-18 6.40182499923028e-17 2.3612013052186654e-17 5689/5682/51807/63943/143471/10381/5705/5709/5695/5711/7846/113457/5683/5699/5702/81027/5696/5691/7314/5718/79861/5700/122706/5707/23198/983/9861/5698/5692/5713/10376/5710/7157/5719/6233/84617/51512/10382/7277/5706/9133/891/5714/5688/5687/347733/5708/22919/5704/3326/7311/10383/5347/84790/5694/7280/5684/5720/5690/5717/9491/10197/7316/10213/1026/5715/5701/5685/3320/5686/5716/5693/5721 73 Human_herpesvirus_8_type_P R-HSA-4086400 PCP/CE pathway 84/5323 92/10654 1.4922753057872862e-17 1.3205228649325231e-16 4.870517879861849e-17 5689/5579/5682/5578/1212/5582/143471/5705/5709/5695/5881/5711/5683/5699/5702/57216/1855/163/5696/5691/4920/7314/5879/5718/2535/161/5700/122706/5707/1856/8322/23198/7471/8323/9861/8321/7481/5698/5880/5692/5713/5710/5719/6233/7474/1857/1213/1211/7855/1175/7976/1173/409/5706/160/5714/5688/5687/5708/5704/7311/387/5694/57154/5684/5720/5690/5717/9491/50855/10197/64750/7316/10213/5216/5715/5701/5685/5686/23513/5716/5693/5721/6259 84 Human_herpesvirus_8_type_P R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 75/5323 80/10654 1.6040658603302612e-17 1.4105754159279233e-16 5.202660981202756e-17 3839/23165/201626/5335/348995/317649/57122/11274/23511/4734/23279/8672/23225/1973/3836/4599/9972/8021/7334/4938/55746/7314/402569/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/1977/51191/6233/5610/4940/6396/129401/4928/3838/5903/55706/7175/2316/4600/8638/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/1974/5595/3837/9631/79023/23636/7316/53371/9688/6041/4939/6059/5300/9775/5495/8480 75 Human_herpesvirus_8_type_P R-HSA-162587 HIV Life Cycle 126/5323 152/10654 1.7363038758368232e-17 1.5173786045356587e-16 5.596585882886917e-17 6884/23165/6875/2237/7852/6874/348995/57122/3981/5431/23511/5435/5433/2960/23279/23327/29082/8732/23225/2965/27183/5439/6873/3836/9972/6881/2967/51616/8021/11198/904/51497/55746/7314/25978/51160/2959/7518/404672/10015/5438/3978/10762/79720/51534/4836/9397/79902/11168/9883/83860/51510/2068/5478/6233/7514/1025/6396/129401/6883/7936/6829/2957/25920/4928/2963/5434/5903/55706/7175/5436/6878/920/4331/4927/8148/2966/2962/54457/8812/128866/905/2071/5901/8086/7311/6880/6908/7251/1104/2547/6882/2961/5432/22916/1234/6877/5905/6917/5440/902/9631/3159/5430/7520/6749/79023/5441/23636/7469/4686/7316/6872/53371/9688/6879/9150/2958/5437/8815/6827/2968/138474/1022/8178/8480 126 Human_herpesvirus_8_type_P R-HSA-2132295 MHC class II antigen presentation 106/5323 123/10654 2.1373820980303413e-17 1.856355933289315e-16 6.846844537550088e-17 64837/162/11127/51807/10484/1174/3798/1785/10381/1780/3115/1509/8655/84516/3109/832/285643/3113/10112/972/7846/5476/3117/113457/9632/81027/6456/11004/3112/163/1759/3127/81930/51164/161/79861/3797/29127/3126/22872/3111/3796/10437/89953/56992/83547/10376/10540/3835/147700/1213/1211/9493/6396/1175/7879/140735/1508/3831/3120/1173/84617/11258/6712/1783/10382/10802/93661/821/55860/830/3123/3832/7277/160/10671/3122/1639/26052/26153/1062/347733/51143/9871/10383/24137/84790/84643/3125/22920/1075/7280/829/1778/114876/164/9371/3119/10120/1512/1781/1513/10121/1520/3799/375 106 Human_herpesvirus_8_type_P R-HSA-6782135 Dual incision in TC-NER 64/5323 66/10654 2.392195810747236e-17 2.0398906095280975e-16 7.523780125667543e-17 2074/5982/7507/5431/5435/9978/5433/57654/2965/5439/2067/2967/6117/10714/91603/7314/6118/404672/3150/5438/5985/2068/5984/6233/7874/5424/8451/10450/5434/5436/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/2071/51426/7311/5983/5432/56655/6917/5440/902/27339/5430/57804/5441/2072/7316/5426/5437/2033/2968/56949/9716/2073/5981/1022 64 Human_herpesvirus_8_type_P R-HSA-69563 p53-Dependent G1 DNA Damage Response 64/5323 66/10654 2.392195810747236e-17 2.0398906095280975e-16 7.523780125667543e-17 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Human_herpesvirus_8_type_P R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 64/5323 66/10654 2.392195810747236e-17 2.0398906095280975e-16 7.523780125667543e-17 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Human_herpesvirus_8_type_P R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 59/5323 60/10654 4.3320484747726516e-17 3.6066226059201897e-16 1.3302397371927235e-16 8454/5689/9134/5682/5705/5709/5753/5695/5711/5683/5699/5702/8900/5696/5691/7314/5718/5700/5707/898/890/9861/6502/5698/5692/5713/595/5710/5719/6233/1163/1019/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/5690/5717/1027/9491/6500/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721 59 Human_herpesvirus_8_type_P R-HSA-5610780 Degradation of GLI1 by the proteasome 59/5323 60/10654 4.3320484747726516e-17 3.6066226059201897e-16 1.3302397371927235e-16 8454/5689/5682/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/83737/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/8650/9861/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/2735/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Human_herpesvirus_8_type_P R-HSA-5610783 Degradation of GLI2 by the proteasome 59/5323 60/10654 4.3320484747726516e-17 3.6066226059201897e-16 1.3302397371927235e-16 8454/5689/5682/1452/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/9861/2932/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/2736/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Human_herpesvirus_8_type_P R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 59/5323 60/10654 4.3320484747726516e-17 3.6066226059201897e-16 1.3302397371927235e-16 8454/5689/5682/1452/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/2737/9861/2932/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Human_herpesvirus_8_type_P R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 63/5323 65/10654 4.6720802358029746e-17 3.866833465749874e-16 1.426213966718803e-16 2074/5982/5431/5435/9978/5433/57654/2965/5439/2967/6117/10714/91603/7314/6118/404672/3150/5438/3978/5985/2068/5984/6233/7874/5424/8451/10450/5434/5436/7515/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/2071/51426/7311/3980/5983/5432/56655/6917/5440/902/27339/5430/57804/5441/7316/5426/5437/2033/2968/56949/9716/5981/1022 63 Human_herpesvirus_8_type_P R-HSA-8948751 Regulation of PTEN stability and activity 66/5323 69/10654 7.359251152559239e-17 6.055243492193478e-16 2.2333707714445707e-16 5689/5682/1459/1460/143471/5705/5709/5695/1457/4734/11060/5711/5683/5699/2444/5702/8975/80351/5696/5691/7314/5718/5700/122706/5707/23198/9861/81847/5698/10000/5692/5713/5710/5719/6233/331/23608/5706/8658/5714/5688/5687/5708/208/5704/7311/5694/5684/5720/10273/207/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5728/5987/5716/5693/5721 66 Human_herpesvirus_8_type_P R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 58/5323 59/10654 8.574665260496943e-17 7.014275593906511e-16 2.58709300699204e-16 5689/5682/143471/5705/5709/5695/84515/4998/5711/5683/990/5699/5702/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/4999/5000/5706/5714/51053/5688/5687/5708/81620/5704/23595/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 58 Human_herpesvirus_8_type_P R-HSA-450294 MAP kinase activation 62/5323 64/10654 9.119689959446261e-17 7.416996400543867e-16 2.735629540618806e-16 8454/3725/9252/4790/1848/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/23118/8517/5528/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/1846/79155/64127/5602/3656/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/7316/7335/4205/466/23291/2002/5609/1385/5599 62 Human_herpesvirus_8_type_P R-HSA-170834 Signaling by TGF-beta Receptor Complex 69/5323 73/10654 9.546668612266331e-17 7.675521564262129e-16 2.830982030584843e-16 892/7321/4738/9372/8239/9612/56937/4609/4089/22938/23327/4088/5499/1030/9110/7040/904/7314/5054/7027/6497/51592/50848/7323/6667/4092/11171/7050/7046/5494/2280/9958/9040/6233/7514/1025/57530/5500/4221/5590/3726/5501/1024/60436/23645/8812/1874/142/905/4087/7048/7311/387/57154/51377/10273/50855/64750/54778/7316/1875/9611/5933/867/3065/6498/56288/25937/23439 69 Human_herpesvirus_8_type_P R-HSA-1980143 Signaling by NOTCH1 69/5323 73/10654 9.546668612266331e-17 7.675521564262129e-16 2.830982030584843e-16 8454/79718/892/182/3091/23385/9978/9759/9612/4609/22938/1387/6907/408/83737/6868/9794/57534/388585/28514/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/7091/8650/102/5664/8850/3066/6233/7089/5663/7090/142678/23220/409/10046/1024/10014/26508/9148/7088/83464/23493/7311/55851/51107/4851/8841/23462/6500/7316/9611/54492/2033/55294/3065/1840/54567/3516 69 Human_herpesvirus_8_type_P R-HSA-5610787 Hedgehog 'off' state 98/5323 113/10654 1.3910994470170858e-16 1.1120891602005908e-15 4.1017465752357863e-16 8454/5689/57728/5682/11127/1452/51684/143471/10381/5705/5709/9978/5695/107/5711/7846/113457/5683/5699/5702/81027/83737/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/112/5573/2737/5727/8650/111/9861/2932/5698/5692/5713/10376/5710/5719/6233/23322/196883/115/84617/54903/10382/5568/7277/5706/113/5714/5566/2736/5688/5687/347733/5708/55811/5577/5704/7311/10383/84790/5694/7280/109/5684/5720/2735/5575/6608/5690/5717/9491/6500/114/7289/10197/108/7316/10213/2778/5715/5701/5576/5685/5686/5716/8481/5693/5721 98 Human_herpesvirus_8_type_P R-HSA-72187 mRNA 3'-end processing 57/5323 58/10654 1.696597774479113e-16 1.3486514512384813e-15 4.974265256129663e-16 8683/6431/84271/51585/199746/81608/1477/65109/9877/7919/53981/6432/8563/6430/11051/80145/8106/22794/9785/11338/4116/1478/51213/10250/26097/51362/23283/10914/57187/79228/84324/6428/10212/55110/84321/6429/10898/10569/9295/51692/9939/6426/22916/1479/10921/79869/29894/4686/8189/10978/7307/9984/10189/9775/84248/6427/55339 57 Human_herpesvirus_8_type_P R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 80/5323 88/10654 1.709142650361158e-16 1.350990847785477e-15 4.982893711579249e-16 5689/5682/5578/26986/143471/5705/5709/5695/5711/1432/5683/5699/5702/11340/8021/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/7534/9261/8741/9861/5698/5692/5713/1981/5710/5719/6233/5580/7514/5600/8570/23016/118460/1994/5073/3315/5706/8125/7538/5714/5688/5687/5708/5704/7311/5694/3304/6418/167227/7529/22894/5684/5720/207/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/55802/51013/5716/5693/54512/5721 80 Human_herpesvirus_8_type_P R-HSA-195258 RHO GTPase Effectors 235/5323 327/10654 2.3661380890774444e-16 1.859863849906125e-15 6.859782875126022e-16 55839/11130/64837/71/6249/51517/5579/9735/7531/5526/51807/10811/10971/5578/9212/3798/388/7533/2810/147841/147179/348995/10381/57122/6280/1780/23122/3688/5048/57405/8655/10094/23279/1432/2017/2491/7846/113457/79784/9475/1060/81027/4628/11004/8976/1855/2885/23433/6093/9184/8826/10499/5518/23332/25909/3071/10726/81930/5062/55746/5879/5515/85415/26999/25/79682/1072/10403/79861/4638/25936/4659/10093/1856/10006/4771/389/5594/3619/64105/7534/332/5528/6714/79902/3796/5519/81565/999/89953/10810/5880/91687/11243/10376/11113/83540/5580/9055/1857/23191/7514/147700/54820/29984/1729/6396/1535/5600/801/64946/9793/30849/10109/5586/140735/5500/10787/4221/805/3831/220134/5170/84617/4928/4688/5590/5903/653361/55055/5747/80776/1783/401541/2316/7532/10382/10627/79172/7277/79980/6232/5501/10152/6279/54821/10092/9183/10163/1062/699/347733/752/22919/55845/5063/3895/5529/51143/998/695/10788/286205/10097/3817/57120/367/10383/5347/387/60/84790/84643/5058/7280/4629/7529/5595/1778/5516/5905/3984/54908/55143/1495/1499/5525/1058/991/79019/4627/348235/80152/10458/1063/3985/54763/6722/8379/1027/1080/23421/79023/55920/6242/1781/10398/4085/5289/5585/5216/10552/55166/8936/4637/995/79003/391/23028/1742/5527/4689/10096/7454/701/23380/9928/29941/3799/103910/57551/5300/808/10095/1536 235 Human_herpesvirus_8_type_P R-HSA-5685942 HDR through Homologous Recombination (HRR) 64/5323 67/10654 2.7309859738538107e-16 2.1347207028957285e-15 7.873544357368006e-16 83990/5892/9156/1763/7486/5982/472/80198/4683/84126/672/6117/10714/348654/83695/7314/6118/5888/116028/197342/7517/84464/5985/5984/6233/5884/5810/5424/80010/7516/54107/580/11073/5425/641/5111/6119/3364/10524/5427/144715/5889/5429/1111/79728/51426/146956/7311/5983/56655/51750/5883/10111/57804/675/545/7316/5426/10635/23514/5932/7156/5890/5981 64 Human_herpesvirus_8_type_P R-HSA-1236974 ER-Phagosome pathway 76/5323 83/10654 3.58187934364708e-16 2.7843669814980343e-15 1.0269651156836352e-15 8773/5689/5682/3107/811/143471/5705/10333/5709/5695/567/3106/5711/5683/929/5699/5702/3133/3551/5696/5691/7314/5718/5700/122706/5707/23198/8517/6810/7096/9861/5698/5692/5713/5710/5719/6233/3135/6890/5706/9554/5714/5688/5687/5708/2923/695/5704/7311/5694/8673/3105/23643/1147/5684/5720/5690/5717/9491/10197/7099/4615/7316/10213/5715/5701/9341/5685/5686/114609/948/5716/3134/7097/5693/5721 76 Human_herpesvirus_8_type_P R-HSA-3928665 EPH-ephrin mediated repulsion of cells 51/5323 51/10654 3.7890701441759945e-16 2.9292426883822113e-15 1.0803999890565444e-15 71/2042/1947/1212/23385/2051/2045/2050/285220/2047/2534/1948/163/284656/1759/5879/161/2046/4313/2041/102/6714/5664/1943/2043/7525/1942/7410/1213/1211/1175/5663/1173/7074/1949/1945/10451/4318/160/2049/8218/4067/2044/2048/83464/60/55851/51107/1946/1944/1969 51 Human_herpesvirus_8_type_P R-HSA-1234174 Cellular response to hypoxia 70/5323 75/10654 3.8370979110927566e-16 2.9341286744062544e-15 1.0822020996388612e-15 5689/5682/64344/7321/3091/143471/5705/5709/9978/5695/5711/1387/5683/5699/7428/5702/2056/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/405/768/112399/84962/5706/5714/10370/5688/5687/5708/5704/7311/2034/55662/5694/5684/5720/7422/5690/5717/9491/10197/7316/10213/8994/7322/5715/5701/112398/5685/5686/2033/8453/5716/54583/5693/5721 70 Human_herpesvirus_8_type_P R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 70/5323 75/10654 3.8370979110927566e-16 2.9341286744062544e-15 1.0822020996388612e-15 23165/8683/6431/84271/199746/348995/57122/23511/65109/23279/23225/9877/9972/8021/55746/7919/6432/8563/6430/56001/80145/10762/22794/9785/11338/29107/4116/79902/9883/51213/10250/26097/51362/57187/6396/129401/79228/2733/84324/4928/5903/55706/7175/6428/10212/55110/84321/6429/4927/10569/9295/10482/8086/9939/6426/22916/10921/9631/79023/23636/4686/53371/7307/9688/9984/10189/9775/84248/6427/8480 70 Human_herpesvirus_8_type_P R-HSA-199977 ER to Golgi Anterograde Transport 125/5323 154/10654 6.314229313124345e-16 4.802227374900515e-15 1.7712176679205134e-15 6811/23256/374/6711/11014/2153/51807/10484/5861/10381/1780/9570/90411/8655/84516/832/3998/55738/7846/113457/51226/9382/375056/9632/3630/81027/6709/10652/54732/51272/51164/58485/79861/9117/4253/2801/377/10466/22872/1315/81562/8615/55014/11316/91949/8729/23423/10376/1314/10540/83696/6399/378/6396/26286/1453/26958/140735/10959/84364/22820/84617/22796/11258/6712/2890/1783/10382/10802/93661/55860/2157/830/7277/10671/9554/966/11196/1639/10282/8775/81876/11015/347733/51143/51693/23243/5537/9871/10383/84790/10945/1075/7280/829/1778/9919/10113/25839/55291/51014/26984/83548/63908/1604/1781/57731/10121/2804/9527/57511/22870/5265/8774/10972/381/4905/9276/287/375/84342/64689/288/22818/372 125 Human_herpesvirus_8_type_P R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 55/5323 56/10654 6.634362706916728e-16 5.01857437023217e-15 1.8510134773683914e-15 5689/5682/26986/143471/5705/5709/5695/5711/5683/5699/5702/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/9861/5698/5692/5713/1981/5710/5719/6233/3315/5706/5714/5688/5687/5708/5704/7311/5694/3304/5684/5720/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 55 Human_herpesvirus_8_type_P R-HSA-8943724 Regulation of PTEN gene transcription 59/5323 61/10654 6.75868456529051e-16 5.085277638162432e-15 1.875615812377271e-15 1912/3725/6591/1822/9112/6045/80012/1911/5928/10325/23512/57332/1107/2475/1386/10670/64121/23186/2146/51564/5594/84232/7101/84733/57459/3066/7157/8726/57521/6015/28956/389541/9219/8535/5931/58528/1108/2122/64223/10014/54815/6009/55004/57504/648/23466/53615/5595/8841/5468/5978/153129/57167/1958/8649/6615/3065/23028/10542 59 Human_herpesvirus_8_type_P R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 72/5323 78/10654 7.176923665335885e-16 5.37124021123808e-15 1.981088111428103e-15 3443/4790/7321/9140/9474/4792/177/3093/1387/64135/83737/7187/1540/3551/7314/3445/6283/8737/29110/4214/28512/9636/841/8517/3444/8887/7323/5970/23586/7128/3451/3448/3661/3439/51191/6233/10010/55593/84282/8772/3452/4791/3446/3665/351/54476/7706/843/3440/9246/7189/7311/79671/5094/9641/3456/28511/1147/3441/7186/57506/3449/84166/7316/4793/3146/7322/2033/6288/54941/6285/5300 72 Human_herpesvirus_8_type_P R-HSA-199418 Negative regulation of the PI3K/AKT network 95/5323 110/10654 7.455753029787952e-16 5.5503939221754756e-15 2.0471658277279095e-15 5295/374/3643/2250/5291/5526/3082/941/2064/145957/2534/9965/2264/3630/3654/9542/2885/51135/8660/5518/2252/5879/5515/23396/1839/5290/3667/8823/90865/2065/3815/5594/2069/8074/57761/2260/5528/2249/6714/2099/2248/5519/2247/5880/10000/7409/2246/2251/3932/118788/5781/940/23239/930/2263/4233/8503/5159/3084/5529/7189/208/10718/5293/1956/2549/5595/3556/5516/685/5305/5525/8870/207/8817/4615/2100/2254/152831/1950/50852/26281/10818/2261/2255/391/5728/2066/27006/942/5527/5155/4254/5296/5156 95 Human_herpesvirus_8_type_P R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 90/5323 103/10654 8.76975277008207e-16 6.494232709213407e-15 2.3952842745985934e-15 5295/374/3643/2250/5291/5526/3082/941/2064/145957/2534/9965/2264/3630/3654/9542/2885/51135/8660/5518/2252/5879/5515/23396/1839/5290/3667/8823/90865/2065/3815/5594/2069/8074/2260/5528/2249/6714/2099/2248/5519/2247/5880/7409/2246/2251/3932/118788/5781/940/930/2263/4233/8503/5159/3084/5529/7189/10718/5293/1956/2549/5595/3556/5516/685/5305/5525/8870/207/8817/4615/2100/2254/152831/1950/50852/26281/10818/2261/2255/391/2066/27006/942/5527/5155/4254/5296/5156 90 Human_herpesvirus_8_type_P R-HSA-3371453 Regulation of HSF1-mediated heat shock response 65/5323 69/10654 1.2505191493196102e-15 9.211939492631893e-15 3.397662940835315e-15 23165/6782/573/7531/9530/348995/472/57122/3313/23511/3305/23279/91582/259217/23225/3309/9531/3306/27000/9972/23411/8021/6117/3312/55746/51182/3303/6118/5594/3308/10049/3337/10762/9261/79902/9883/2932/6396/129401/3297/4928/5903/55706/7175/4927/6119/57805/3310/7266/8086/3304/5595/9631/116835/545/79023/23636/10808/53371/9532/9688/6767/22824/9529/8480 65 Human_herpesvirus_8_type_P R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 54/5323 55/10654 1.3111395650066074e-15 9.496207524585858e-15 3.5025102379986e-15 8454/5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/26271/5706/5714/5688/5687/5708/5704/51343/7311/5694/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 54 Human_herpesvirus_8_type_P R-HSA-4641257 Degradation of AXIN 54/5323 55/10654 1.3111395650066074e-15 9.496207524585858e-15 3.5025102379986e-15 5689/5682/143471/5705/5709/5695/5711/5683/5699/8312/5702/80351/5696/5691/7314/5718/5700/122706/5707/23198/9861/81847/5698/5692/5713/5710/8313/5719/6233/5706/8658/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/5716/5693/5721 54 Human_herpesvirus_8_type_P R-HSA-8941858 Regulation of RUNX3 expression and activity 54/5323 55/10654 1.3111395650066074e-15 9.496207524585858e-15 3.5025102379986e-15 5689/5682/5705/5709/5695/5711/5683/5699/5702/7040/5696/5691/7314/5718/5700/5707/865/6714/9861/5698/5692/5713/5710/5719/6233/1029/864/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/2033/5716/5693/5721/4193 54 Human_herpesvirus_8_type_P R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 58/5323 60/10654 1.316105520464991e-15 9.496207524585858e-15 3.5025102379986e-15 8454/5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/5970/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 58 Human_herpesvirus_8_type_P R-HSA-9009391 Extra-nuclear estrogen signaling 71/5323 77/10654 1.3357817955636293e-15 9.589005032438911e-15 3.5367369775127252e-15 5295/2788/374/4893/857/2770/2782/3845/3265/8877/2773/2787/1839/5290/4316/5594/2069/10681/4313/2792/6714/2099/10000/2785/595/2783/2784/2771/7514/2353/801/2791/805/5170/5590/6464/5747/1903/3315/4318/8503/2786/208/1956/858/3480/5595/596/685/54331/2309/59345/207/6722/1027/51764/94235/2100/1950/55970/4314/346562/2793/3320/4846/2002/1385/5296/808/3276/2790 71 Human_herpesvirus_8_type_P R-HSA-8939902 Regulation of RUNX2 expression and activity 68/5323 73/10654 1.3568377029627904e-15 9.690713949587036e-15 3.5742505346548536e-15 8454/5689/7291/5682/143471/5705/5709/9978/5695/5711/650/5683/1749/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/865/11059/2099/9861/2932/6502/5698/5692/5713/5710/5719/6233/5706/5714/6772/5688/5687/2908/5708/4488/5704/7311/860/1750/5694/57154/5684/5720/10273/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721/10891 68 Human_herpesvirus_8_type_P R-HSA-111885 Opioid Signalling 81/5323 91/10654 2.207291149828813e-15 1.5685144685904748e-14 5.785191583549203e-15 2788/2780/5331/2770/817/5578/5582/2775/5530/107/4988/2782/5499/5518/814/2773/5515/2787/818/84152/5567/5594/10681/112/5573/5528/111/5443/2792/5519/2785/2783/2784/5613/2771/5332/5580/196883/115/801/2791/805/3838/2781/5568/113/10645/5566/84254/23236/816/2786/5577/1020/5141/109/5516/5533/815/5321/54331/5575/59345/5532/51764/94235/114/5330/108/2779/5173/55970/10768/346562/2793/5576/5534/1385/5144/808/2790 81 Human_herpesvirus_8_type_P R-HSA-1169408 ISG15 antiviral mechanism 67/5323 72/10654 2.547461903946272e-15 1.8011451753027158e-14 6.64320930254172e-15 3839/23165/5335/348995/317649/57122/11274/23511/4734/23279/8672/23225/1973/3836/4599/9972/8021/7334/55746/7314/402569/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/1977/51191/6233/5610/6396/129401/4928/3838/5903/55706/7175/4600/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/1974/5595/3837/9631/79023/23636/7316/53371/9688/5300/9775/5495/8480 67 Human_herpesvirus_8_type_P R-HSA-5676590 NIK-->noncanonical NF-kB signaling 57/5323 59/10654 2.5611838354718607e-15 1.801792828254454e-14 6.645598057303303e-15 8454/5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 57 Human_herpesvirus_8_type_P R-HSA-9604323 Negative regulation of NOTCH4 signaling 53/5323 54/10654 2.590112791461511e-15 1.8130789540230575e-14 6.687224960411233e-15 8454/5689/5682/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/5707/7534/9861/5698/5692/5713/5710/5719/6233/5706/10460/5714/5688/5687/5708/4855/5704/7311/5694/5684/5720/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721 53 Human_herpesvirus_8_type_P R-HSA-5621481 C-type lectin receptors (CLRs) 116/5323 142/10654 2.8793373286028753e-15 2.0055582283882406e-14 7.397151136014683e-15 8454/5689/4586/9252/4893/4790/5682/7321/29108/143471/5705/5530/5709/5695/4792/5711/1387/5683/2534/5699/5702/5894/64170/3845/7334/3265/3551/5062/5696/5691/7314/257397/5718/8945/4773/5700/122706/5707/5567/5336/4582/23198/23118/10892/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/801/4791/805/5170/4772/5568/4775/5706/64581/6850/8915/5714/5566/5688/5687/4067/5708/5063/7189/5704/30835/7311/5971/5694/5058/997/1147/5684/5720/6885/4584/84433/5690/3553/5532/5717/9491/6500/10197/7316/10213/7335/10768/7322/5715/93978/5701/23291/5685/5686/2033/5534/5716/808/5693/5721/2207 116 Human_herpesvirus_8_type_P R-HSA-1226099 Signaling by FGFR in disease 60/5323 63/10654 3.726008366707609e-15 2.5825092472697567e-14 9.525134170530732e-15 5295/4893/11052/2250/5335/9530/613/5431/6776/5435/5433/11064/5439/2264/2885/9846/2252/3845/3265/7750/8805/26127/5290/8823/8074/2260/5438/2249/2248/399687/2247/2246/2251/6777/1523/2963/5434/5436/9208/6774/2263/6772/2962/6654/11160/2549/5432/22916/5440/5430/8817/5441/2254/4686/26281/10818/2261/5437/2255/27006 60 Human_herpesvirus_8_type_P R-HSA-73856 RNA Polymerase II Transcription Termination 63/5323 67/10654 4.500763995810845e-15 3.104203402993068e-14 1.1449311919167941e-14 8683/6431/84271/51585/199746/81608/1477/65109/9877/7919/53981/6432/8563/6430/11051/80145/8106/22794/9785/11338/4116/1478/51213/10250/26097/51362/23283/6636/10914/57187/79228/84324/6635/7884/6428/10212/6637/55110/84321/6429/10898/10569/9295/51692/9939/6426/22916/1479/10921/79869/29894/4686/8189/10978/7307/9984/10189/6634/9775/84248/6427/55339/6628 63 Human_herpesvirus_8_type_P R-HSA-983169 Class I MHC mediated antigen processing & presentation 258/5323 371/10654 5.802757937122813e-15 3.982673374405755e-14 1.4689394931972003e-14 8454/8773/5689/127544/11065/55070/5682/55819/8916/3107/7321/9021/8697/10484/9817/7174/811/143471/5705/10333/9690/8452/5709/9978/5695/567/55236/54620/4734/7337/3693/84676/7704/3106/3093/5711/23327/51465/10616/5683/929/3309/25898/5699/7328/9632/7428/5702/22954/83737/51529/10075/29945/79176/8924/56658/51434/6468/10425/25793/3133/51666/90293/54461/29882/7334/55182/4591/3551/7332/5696/5691/9820/55658/7314/996/9354/5718/197131/8945/64410/51320/5700/122706/5707/10477/148581/23198/10533/51130/8517/6810/6477/7323/22872/4008/7096/84861/11059/26118/51433/9861/26249/55905/10134/6502/5698/5692/5713/9903/26190/79654/5710/9040/7324/5719/64682/8925/51191/6233/3685/26091/6047/868/6396/127247/1535/5930/26268/115290/51725/140459/23608/55585/64320/899/3135/23352/26224/4688/653361/142678/246184/151636/11146/10802/6890/821/81559/2209/144699/5706/79876/26263/9554/8881/7317/80196/84078/5714/26272/8651/64219/5688/55336/5687/26270/63893/5708/55008/2923/10422/695/90933/63891/9246/10393/5704/9870/9520/25847/51343/7311/9871/9320/26232/57520/5694/8673/3105/997/7325/140691/23643/57154/1147/5684/6737/8065/5720/84708/7319/54850/26046/991/10273/7320/5690/5717/9491/6500/26259/10197/7099/53339/7336/4615/64750/51619/54778/7316/10213/7335/222235/25831/7322/5715/5701/9341/23291/5685/5686/55521/114609/55294/135892/8453/80176/8139/126433/4689/26267/948/1520/5716/55284/3134/80204/27338/7097/23014/1536/90678/5693/5721/51676/642/4360 258 Human_herpesvirus_8_type_P R-HSA-167161 HIV Transcription Initiation 47/5323 47/10654 6.193442087495409e-15 4.015747934150249e-14 1.4811384667160985e-14 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_herpesvirus_8_type_P R-HSA-167162 RNA Polymerase II HIV Promoter Escape 47/5323 47/10654 6.193442087495409e-15 4.015747934150249e-14 1.4811384667160985e-14 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_herpesvirus_8_type_P R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 47/5323 47/10654 6.193442087495409e-15 4.015747934150249e-14 1.4811384667160985e-14 8454/79718/892/3091/9978/9759/9612/4609/22938/1387/6907/9794/388585/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/7091/8850/3066/6233/7089/7090/10046/1024/10014/26508/7088/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 47 Human_herpesvirus_8_type_P R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 47/5323 47/10654 6.193442087495409e-15 4.015747934150249e-14 1.4811384667160985e-14 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Human_herpesvirus_8_type_P R-HSA-6802949 Signaling by RAS mutants 47/5323 47/10654 6.193442087495409e-15 4.015747934150249e-14 1.4811384667160985e-14 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Human_herpesvirus_8_type_P R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 47/5323 47/10654 6.193442087495409e-15 4.015747934150249e-14 1.4811384667160985e-14 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Human_herpesvirus_8_type_P R-HSA-73762 RNA Polymerase I Transcription Initiation 47/5323 47/10654 6.193442087495409e-15 4.015747934150249e-14 1.4811384667160985e-14 2074/9112/5435/5928/2965/64425/1107/2967/2648/30834/404672/8850/57459/2068/3066/9533/5434/9015/79101/9219/5931/221830/7270/4331/9013/1108/2966/54815/2071/10849/57504/6908/53615/5440/902/9014/25885/54700/5441/51082/7343/5437/3065/2968/84172/1022/10919 47 Human_herpesvirus_8_type_P R-HSA-73776 RNA Polymerase II Promoter Escape 47/5323 47/10654 6.193442087495409e-15 4.015747934150249e-14 1.4811384667160985e-14 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_herpesvirus_8_type_P R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 47/5323 47/10654 6.193442087495409e-15 4.015747934150249e-14 1.4811384667160985e-14 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_herpesvirus_8_type_P R-HSA-75953 RNA Polymerase II Transcription Initiation 47/5323 47/10654 6.193442087495409e-15 4.015747934150249e-14 1.4811384667160985e-14 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_herpesvirus_8_type_P R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 47/5323 47/10654 6.193442087495409e-15 4.015747934150249e-14 1.4811384667160985e-14 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_herpesvirus_8_type_P R-HSA-9649948 Signaling downstream of RAS mutants 47/5323 47/10654 6.193442087495409e-15 4.015747934150249e-14 1.4811384667160985e-14 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Human_herpesvirus_8_type_P R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 110/5323 134/10654 7.792234647575684e-15 5.029208325293114e-14 1.854935625907684e-14 5579/2153/7042/5175/3959/5578/5582/3082/29106/7423/3920/374354/2244/7114/3309/3690/2162/87/10487/7040/5874/54863/350/7043/967/5054/5099/1072/7018/6678/5340/813/7094/7414/10490/83706/7044/6810/7123/6694/3671/7273/22927/1191/3273/27154/226/2335/1/5478/94121/22915/2266/7076/2243/801/805/351/135228/51097/7424/2316/3674/5552/2157/7277/334/10447/335/308/78991/197/81/9948/3481/5473/8407/7450/29789/10916/139322/5005/7422/5004/5196/3827/1950/2621/5216/5768/710/6647/5265/7078/55664/5345/54676/2/948/88/1675/3479/5155/51368/808/213/5660/7057/5627/6814 110 Human_herpesvirus_8_type_P R-HSA-1236975 Antigen processing-Cross presentation 86/5323 99/10654 8.430205843598317e-15 5.4161185488323436e-14 1.9976407021840766e-14 8773/5689/5682/3107/811/143471/5705/10333/5709/5695/567/3693/3106/5711/5683/929/5699/5702/3133/3551/5696/5691/7314/5718/5700/122706/5707/23198/8517/6810/7096/9861/5698/5692/5713/5710/5719/6233/3685/1535/3135/4688/653361/6890/2209/5706/9554/5714/5688/5687/5708/2923/695/5704/7311/5694/8673/3105/23643/1147/5684/5720/5690/5717/9491/10197/7099/4615/7316/10213/5715/5701/9341/5685/5686/114609/4689/948/1520/5716/3134/7097/1536/5693/5721/4360 86 Human_herpesvirus_8_type_P R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 62/5323 66/10654 8.525901760826357e-15 5.452701717037584e-14 2.011133764635117e-14 5689/5682/64344/7321/3091/143471/5705/5709/9978/5695/5711/5683/5699/7428/5702/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/112399/84962/5706/5714/5688/5687/5708/5704/7311/2034/5694/5684/5720/5690/5717/9491/10197/7316/10213/8994/7322/5715/5701/112398/5685/5686/8453/5716/54583/5693/5721 62 Human_herpesvirus_8_type_P R-HSA-69541 Stabilization of p53 55/5323 57/10654 9.679945273981772e-15 6.162752488910567e-14 2.2730235866030075e-14 5689/5682/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/51230/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721/4193 55 Human_herpesvirus_8_type_P R-HSA-180534 Vpu mediated degradation of CD4 51/5323 52/10654 1.0094800439568236e-14 6.25699745307159e-14 2.307784195087939e-14 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/920/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_herpesvirus_8_type_P R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 51/5323 52/10654 1.0094800439568236e-14 6.25699745307159e-14 2.307784195087939e-14 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_herpesvirus_8_type_P R-HSA-69610 p53-Independent DNA Damage Response 51/5323 52/10654 1.0094800439568236e-14 6.25699745307159e-14 2.307784195087939e-14 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_herpesvirus_8_type_P R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 51/5323 52/10654 1.0094800439568236e-14 6.25699745307159e-14 2.307784195087939e-14 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_herpesvirus_8_type_P R-HSA-72165 mRNA Splicing - Minor Pathway 51/5323 52/10654 1.0094800439568236e-14 6.25699745307159e-14 2.307784195087939e-14 6633/6431/4904/51639/23450/5431/5435/5433/9416/8233/23020/5439/9410/10907/10262/6432/83443/10081/5438/9343/6636/2963/6635/5434/6632/24148/154007/5436/6637/55954/57819/2962/6426/5432/22916/23451/5440/55599/5430/85437/11325/5441/79622/10594/4686/5437/11066/6634/6427/10992/6628 51 Human_herpesvirus_8_type_P R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 51/5323 52/10654 1.0094800439568236e-14 6.25699745307159e-14 2.307784195087939e-14 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/2932/5698/5692/5713/595/5710/5719/6233/1019/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_herpesvirus_8_type_P R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 143/5323 185/10654 1.2407160736464847e-14 7.656524191318439e-14 2.8239751814760716e-14 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/84135/27043/6224/6146/6154/88745/6202/51096/6169/55272/6175/6218/6173/6167/116832/23481/51077/6156/81875/117246/6143/6139/23160/26168/11340/3921/10607/10799/6208/6170/22984/10813/6203/6147/8568/6222/1454/6134/6155/9724/6231/6142/23521/54555/5822/6207/10969/6233/6188/54881/1453/4691/23016/118460/200916/6122/6230/2091/55127/8602/6194/6166/8780/9277/84128/6136/6125/6232/134430/6160/65083/6193/10200/6210/6229/6205/11056/55131/140801/6235/55720/6181/55759/705/7311/6223/25873/26354/51202/9045/6187/6168/6157/6137/79050/22894/84946/6144/9349/55813/4736/57418/22803/51121/6159/25879/6217/81887/6152/57050/51065/6141/6123/55781/6164/6209/11224/6165/6130/6204/6228/51013/6124/83732/27341/6189/6135/6201/6161/54512/10885/6133/9188 143 Human_herpesvirus_8_type_P R-HSA-162599 Late Phase of HIV Life Cycle 113/5323 139/10654 1.2939508954764945e-14 7.950169912381781e-14 2.932281275430531e-14 6884/23165/6875/6874/348995/57122/5431/23511/5435/5433/2960/23279/23327/29082/8732/23225/2965/27183/5439/6873/9972/6881/2967/51616/8021/11198/904/51497/55746/7314/25978/51160/2959/404672/10015/5438/10762/79720/51534/4836/9397/79902/9883/83860/51510/2068/5478/6233/7514/1025/6396/129401/6883/7936/6829/2957/25920/4928/2963/5434/5903/55706/7175/5436/6878/4331/4927/8148/2966/2962/54457/8812/128866/905/2071/5901/8086/7311/6880/6908/7251/1104/6882/2961/5432/22916/6877/5905/6917/5440/902/9631/5430/6749/79023/5441/23636/7469/4686/7316/6872/53371/9688/6879/9150/2958/5437/6827/2968/138474/1022/8178/8480 113 Human_herpesvirus_8_type_P R-HSA-5654738 Signaling by FGFR2 67/5323 73/10654 1.5842765481595278e-14 9.691639579393286e-14 3.574591937037288e-14 5295/4893/2250/5335/54845/5431/5435/5433/8569/5439/7072/2885/7073/5518/2252/3845/3265/7314/5515/5290/8823/5594/8074/5438/3185/2249/6714/2248/4670/2247/6233/2246/2251/5781/5725/2963/5434/6464/5436/673/2263/2962/6654/7311/2549/5432/22916/5595/5516/10253/5440/23543/5430/3178/8817/10817/5441/2254/4686/7316/26281/10818/867/5437/2255/27006/3187 67 Human_herpesvirus_8_type_P R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 54/5323 56/10654 1.8799128511509274e-14 1.1450378275192013e-13 4.223271978206459e-14 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/51009/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/9861/5698/5692/5713/5710/5719/6233/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 54 Human_herpesvirus_8_type_P R-HSA-8868773 rRNA processing in the nucleus and cytosol 149/5323 195/10654 1.9667145809014124e-14 1.1927445755725375e-13 4.3992299835952645e-14 6158/6138/6227/6206/6234/6191/6128/6132/6129/55226/6176/84135/27043/6224/6146/6154/88745/6202/51096/6169/55272/6175/6218/6173/6167/116832/23481/51077/6156/81875/117246/6143/6139/23160/26168/11340/3921/10607/10799/6208/6170/22984/10813/6203/51504/6147/8568/27292/6222/1454/6134/6155/9724/6231/6142/23521/54555/5822/6207/10969/6233/6188/54881/1453/4691/23016/118460/200916/6122/6230/2091/55127/8602/6194/6166/8780/9277/84128/6136/6125/4839/6232/134430/6160/65083/6193/10200/6210/6229/6205/11056/55131/140801/6235/55720/6181/55759/705/7311/6223/25873/55505/26354/51202/9045/6187/6168/6157/6137/79050/22894/84946/6144/9349/55813/4736/57418/22803/51121/6159/25879/6217/81887/6152/57050/51065/6141/6123/55781/6164/6209/11224/6165/6130/6204/1736/6228/51013/6124/83732/27341/6189/6135/6201/6161/54512/10885/6133/9188 149 Human_herpesvirus_8_type_P R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 66/5323 72/10654 2.931004559401305e-14 1.7699242124796723e-13 6.528056235757144e-14 8773/55763/5563/71/7531/11127/51807/10971/7533/2810/53632/10381/60412/5898/7846/113457/81027/51552/23433/5879/79861/51422/4644/7534/6810/5872/4641/10376/11336/6844/9882/79058/801/4218/805/84617/7532/10382/7277/23216/5571/347733/208/5867/10383/60/84790/5564/5565/22920/7280/7529/55770/23265/6517/10890/9371/10640/4627/207/8766/149371/9847/808/54536/6814 66 Human_herpesvirus_8_type_P R-HSA-4608870 Asymmetric localization of PCP proteins 60/5323 64/10654 3.0500065660846315e-14 1.8339142044790925e-13 6.764072141609192e-14 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/57216/5696/5691/7314/5718/2535/5700/122706/5707/1856/8322/23198/9861/8321/5698/5692/5713/5710/5719/6233/7474/7855/7976/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/50855/10197/64750/7316/10213/5715/5701/5685/5686/23513/5716/5693/5721 60 Human_herpesvirus_8_type_P R-HSA-5358351 Signaling by Hedgehog 119/5323 149/10654 3.074543625525478e-14 1.8408012260061052e-13 6.789473717285827e-14 8454/5689/57728/5682/11127/22873/1452/51684/143471/10381/5705/8452/5709/9978/5695/107/5711/7846/113457/5683/408/5699/6400/5702/81027/83737/6868/51009/6469/5696/5691/7314/5718/8945/5700/122706/5707/5567/10956/23198/112/5573/2737/5727/8650/111/9861/8405/2932/5698/5692/5713/10376/5710/5719/6233/23322/196883/115/84617/54903/91653/10382/5568/409/79577/7277/5706/113/84447/5714/5566/2736/5688/5687/347733/5708/55811/25989/5577/5704/7311/147111/10383/84790/5694/7280/109/57154/5684/5720/2735/5575/6608/5690/5717/9491/6500/114/7289/10197/108/64750/132884/7316/10213/2778/50937/7415/5715/5701/5576/5685/5686/5716/8481/5693/5721/5034 119 Human_herpesvirus_8_type_P R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 49/5323 50/10654 3.927283621522686e-14 2.3413932438484825e-13 8.635819917086014e-14 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 49 Human_herpesvirus_8_type_P R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 94/5323 112/10654 4.82864136807715e-14 2.866623799529346e-13 1.0573041059125185e-13 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6728/6173/6167/116832/6156/6143/6139/3921/6208/6170/6203/6147/6222/6727/6184/58477/6134/6747/6731/6155/6231/6142/23521/6185/6207/6233/6188/200916/6122/6230/6194/6166/1650/6136/6125/6232/6160/6748/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/6730/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 94 Human_herpesvirus_8_type_P R-HSA-983189 Kinesins 56/5323 59/10654 5.014813849703482e-14 2.964639952324706e-13 1.0934556514391054e-13 64837/11127/51807/3798/10381/285643/10112/64147/7846/113457/81027/11004/10749/81930/113220/79861/3797/29127/55605/3796/124602/55614/89953/56992/10376/3835/147700/3833/9493/3831/84617/9585/10382/3832/7277/23303/26153/1062/146909/347733/90990/23046/10383/24137/84790/84643/22920/7280/55582/9371/23095/547/3834/55083/3799/221458 56 Human_herpesvirus_8_type_P R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 52/5323 54/10654 7.074863666002405e-14 4.1476388241939096e-13 1.529784117254029e-13 2074/7507/5431/5435/9978/5433/10980/57654/2965/5439/10987/2967/91603/7314/404672/3150/5438/10920/2068/6233/7874/8451/10450/5434/5436/8450/4331/2966/1161/1642/2071/2873/7311/8533/5432/51138/9318/6917/5440/902/27339/5430/5441/7316/64708/5437/2033/2968/56949/9716/1022/50813 52 Human_herpesvirus_8_type_P R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 52/5323 54/10654 7.074863666002405e-14 4.1476388241939096e-13 1.529784117254029e-13 8454/5689/5682/143471/5705/5709/9978/5695/6790/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 52 Human_herpesvirus_8_type_P R-HSA-9012852 Signaling by NOTCH3 48/5323 49/10654 7.740697782708153e-14 4.5191542656723533e-13 1.6668110971282463e-13 4904/182/23385/11060/22938/1387/9794/57534/9787/388585/28514/7314/23286/2648/55534/3280/84441/4854/3714/102/5664/8850/5087/2173/6233/5663/23129/142678/171558/10460/10046/6772/26508/9148/83464/23493/7311/1956/55851/51107/4851/23462/7316/1950/54492/2033/54567/3516 48 Human_herpesvirus_8_type_P R-HSA-72312 rRNA processing 154/5323 205/10654 9.087167827881651e-14 5.283324435466728e-13 1.948661913503982e-13 6158/6138/6227/6206/6234/6191/6128/6132/6129/55226/6176/84135/27043/6224/6146/6154/88745/6202/51096/6169/55272/6175/6218/6173/387338/6167/116832/23481/51077/6156/81875/117246/6143/6139/23160/26168/11340/3921/10607/10799/6208/6170/22984/10813/60528/6203/51504/6147/8568/27292/6222/1454/6134/6155/9724/6231/6142/23521/54555/5822/6207/10969/6233/6188/54881/1453/4691/23016/118460/200916/6122/6230/2091/55127/8602/6194/6166/3028/8780/9277/84128/6136/6125/4839/6232/134430/6160/65083/6193/10200/6210/6229/6205/11056/55131/140801/6235/55720/6181/55759/705/7311/6223/25873/55505/26354/51202/9045/51106/6187/6168/6157/6137/79050/22894/84946/6144/9349/55813/4736/57418/22803/51121/6159/25879/6217/81887/6152/57050/51065/6141/6123/55781/6164/54931/6209/11224/6165/6130/6204/1736/6228/51013/6124/83732/27341/6189/6135/6201/6161/54512/10885/6133/9188 154 Human_herpesvirus_8_type_P R-HSA-114608 Platelet degranulation 105/5323 129/10654 9.667916405440015e-14 5.597842955742429e-13 2.0646665747809956e-13 2153/7042/5175/3959/3082/29106/7423/3920/374354/2244/7114/3309/3690/2162/87/10487/7040/5874/54863/350/7043/967/5054/5099/1072/7018/6678/5340/813/7094/7414/10490/83706/7044/7123/6694/3671/7273/22927/1191/3273/27154/226/2335/1/5478/94121/22915/2266/7076/2243/801/805/351/135228/51097/7424/2316/3674/5552/2157/7277/334/10447/335/308/78991/197/81/9948/3481/5473/8407/7450/29789/10916/139322/5005/7422/5004/5196/3827/1950/2621/5216/5768/710/6647/5265/7078/55664/5345/54676/2/948/88/1675/3479/5155/51368/808/213/5660/7057/5627 105 Human_herpesvirus_8_type_P R-HSA-388841 Costimulation by the CD28 family 64/5323 70/10654 9.992693852384847e-14 5.762180430453065e-13 2.1252795812017816e-13 5295/5777/5526/151888/941/3115/3113/3117/2534/2885/2475/5518/3127/5062/5879/5515/1326/5290/5133/8764/57761/3126/5528/9020/6714/5519/29126/10000/1445/916/7525/7409/3932/5781/1493/940/253260/3120/5170/3123/80380/3122/920/64223/8503/4067/5063/5529/998/208/79109/3125/5058/5516/5525/3119/207/919/55615/915/917/942/5527/5296 64 Human_herpesvirus_8_type_P R-HSA-5696395 Formation of Incision Complex in GG-NER 43/5323 43/10654 1.0108103388109868e-13 5.804939374314524e-13 2.1410504706071603e-13 6613/7507/9978/85015/2965/2067/2967/6612/6117/7334/7314/6118/404672/9557/1643/2068/6233/5886/8451/8554/8450/4331/2966/6119/1642/142/2071/1069/7329/7311/10038/902/7336/2072/54778/7316/7341/10401/2968/5887/2073/1022/7508 43 Human_herpesvirus_8_type_P R-HSA-166520 Signaling by NTRKs 86/5323 101/10654 1.05665492356483e-13 6.043550721364698e-13 2.229058097207793e-13 5295/627/9252/4893/5335/5291/1848/1785/5605/5898/1432/2534/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5879/5515/5607/161/5290/3667/1849/5594/5528/9261/6714/5519/5598/4208/4909/4914/6195/1213/1211/5600/1175/6300/5781/1846/25920/4908/1173/6464/2904/7074/160/673/6774/26052/2889/6654/387/2549/1020/4916/7529/5595/25759/5516/1845/4915/5604/10817/4205/57498/10818/466/53358/4803/2002/1398/1385/5906/8851/5296/581 86 Human_herpesvirus_8_type_P R-HSA-4086398 Ca2+ pathway 58/5323 62/10654 1.086369539410379e-13 6.188347943119041e-13 2.2824640227117705e-13 2788/2780/5158/5331/5578/27327/2775/5530/2782/192669/6932/4343/5593/3845/2787/51176/2535/51701/8322/10681/83439/8323/2792/7481/2785/2783/2784/7474/7855/26523/801/2791/7976/805/5145/4772/6934/5148/23236/2786/27161/815/54331/6885/1499/59345/5532/57690/51764/94235/5330/192670/55970/2793/5534/23112/808/2790 58 Human_herpesvirus_8_type_P R-HSA-674695 RNA Polymerase II Pre-transcription Events 74/5323 84/10654 1.2919501363720537e-13 7.329733233368869e-13 2.70344404597378e-13 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/11198/904/51497/4300/80349/2959/404672/5438/83860/2068/1025/23168/6883/7936/6829/2957/123169/25920/2963/5434/5436/9646/6878/79577/4331/8148/2966/2962/54457/8812/905/2071/27125/6880/6908/6882/2961/5432/22916/55840/6877/6917/5440/902/6830/5430/6749/5441/7469/4686/6872/6879/9150/54623/2958/5437/6827/2968/138474/1022/8178 74 Human_herpesvirus_8_type_P R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 47/5323 48/10654 1.5249402369554513e-13 8.616830977495261e-13 3.1781675621181045e-13 5295/5777/1437/5291/6776/3558/3717/2534/3563/2885/9846/1399/7314/3635/5290/1439/7534/3718/3567/6233/7525/7409/6777/5781/3562/6464/1438/6850/5566/8503/2889/4067/29760/3636/6654/3716/7311/5293/3561/3568/7316/3560/3055/867/1398/5296/3559 47 Human_herpesvirus_8_type_P R-HSA-187037 Signaling by NTRK1 (TRKA) 71/5323 80/10654 1.7432983166724053e-13 9.811282926232297e-13 3.618720295239983e-13 5295/9252/4893/5335/5291/1848/1785/5605/5898/1432/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5515/5607/161/5290/3667/1849/5594/5528/9261/6714/5519/5598/4208/4914/6195/1213/1211/5600/1175/6300/1846/1173/6464/160/673/6774/26052/2889/6654/387/7529/5595/25759/5516/1845/4915/5604/4205/57498/10818/466/53358/4803/2002/1398/1385/5906/5296 71 Human_herpesvirus_8_type_P R-HSA-4641258 Degradation of DVL 54/5323 57/10654 1.829444267870042e-13 1.0255091971685853e-12 3.782411507904931e-13 5689/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/1855/5696/5691/7314/5718/5700/122706/5707/1856/23198/9861/5698/5692/5713/5710/5719/6233/1857/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/23072/5693/5721 54 Human_herpesvirus_8_type_P R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 57/5323 61/10654 2.046796804832031e-13 1.142794882697884e-12 4.214999268096038e-13 71/51517/147179/10094/8976/2885/3071/5879/26999/25/1072/10093/10006/4771/5594/4644/4641/10810/7410/7409/23191/10109/10787/2214/5747/2209/10451/1793/6850/10152/10092/4650/10163/55845/998/695/3326/10097/60/5058/63916/5595/3984/4627/10458/919/10552/4620/8936/917/3320/1398/10096/7454/9844/10095/2212 57 Human_herpesvirus_8_type_P R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/5323 52/10654 2.654387243647313e-13 1.476175040241806e-12 5.444613734629189e-13 5689/5682/143471/472/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Human_herpesvirus_8_type_P R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 75/5323 86/10654 2.8987669786276733e-13 1.6057343066650144e-12 5.922470453640461e-13 5295/5335/71/51517/5291/2268/147179/10094/2534/8976/2885/3071/5879/26999/25/1072/5290/10093/10006/5336/4771/5594/4644/8398/4641/6714/10810/7525/7410/5580/7409/23191/10109/10787/2214/5747/2209/10451/1793/6850/10152/5337/10092/4650/10163/4067/55845/998/695/3326/10097/60/5058/63916/5595/3984/4627/10458/919/3055/10552/10768/4620/8936/917/3320/1398/10096/7454/9844/5296/5581/5338/10095/2212 75 Human_herpesvirus_8_type_P R-HSA-5696400 Dual Incision in GG-NER 41/5323 41/10654 4.0812247952462913e-13 2.251875798788836e-12 8.305650460501225e-13 5982/7507/9978/2965/2067/2967/6117/10714/7314/6118/404672/9557/1643/5985/2068/5984/6233/5424/8451/54107/8450/5425/5111/2966/6119/5427/1642/142/2071/51426/7311/5983/10038/56655/57804/2072/7316/5426/2968/2073/5981 41 Human_herpesvirus_8_type_P R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 67/5323 75/10654 4.104159202687944e-13 2.255684374289819e-12 8.319697725843572e-13 5295/374/2250/5291/3082/941/2064/145957/2534/9965/2264/9542/2885/8660/2252/5879/1839/5290/3667/8823/2065/3815/2069/8074/2260/2249/6714/2099/2248/2247/5880/7409/2246/2251/3932/118788/5781/940/930/2263/4233/8503/5159/3084/10718/5293/1956/2549/685/8817/2100/2254/152831/1950/50852/26281/10818/2261/2255/391/2066/27006/942/5155/4254/5296/5156 67 Human_herpesvirus_8_type_P R-HSA-1632852 Macroautophagy 81/5323 95/10654 4.773386737475921e-13 2.6132899375986853e-12 9.638663369140404e-13 9927/5563/65018/1459/9140/8878/1460/53632/84938/115201/9474/8655/1457/10325/29082/9776/55054/55062/2475/84557/10670/3312/64121/7314/64422/139341/25978/60673/9821/51422/7249/10533/192111/440738/6714/8408/84971/123/55669/6233/9804/30849/51001/57521/140735/28956/7405/389541/79065/22863/58528/7416/26100/64223/5571/128866/6009/55004/7311/5562/11345/55626/5564/5565/7248/11337/10452/8897/64419/153129/7316/83734/5289/8678/10226/8649/81631/10542/23710/54543/23192 81 Human_herpesvirus_8_type_P R-HSA-69481 G2/M Checkpoints 129/5323 168/10654 5.997651888977337e-13 3.2708124836399662e-12 1.2063820405001337e-12 5689/83990/5682/9156/1763/7531/7486/10971/5982/7533/2810/11200/143471/472/5705/5709/4174/5695/84515/4998/5711/4683/10926/5683/990/165918/84126/5699/5702/8924/55388/672/6117/7334/5001/7465/5696/83695/5691/7314/5718/6118/23594/5700/122706/5707/51588/51720/23198/63967/7534/993/116028/983/9861/9656/5698/5692/5985/5713/4175/5710/7157/5984/5719/6233/7158/5884/5810/4999/4172/80010/5000/8318/51512/7532/4173/5706/9133/580/11073/891/641/5714/6119/3364/10524/5688/5687/144715/5708/1111/5704/23595/7311/5983/5694/4176/7529/1017/5684/5720/5883/10111/8317/5690/5717/9491/545/10197/7336/29086/7316/10213/4171/5715/9088/7341/5701/5685/5686/995/5716/5932/9025/79184/7156/5693/5721 129 Human_herpesvirus_8_type_P R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 52/5323 55/10654 6.646880150301447e-13 3.596984758259283e-12 1.3266849854650258e-12 834/4790/7295/29108/1432/10628/5603/83737/3654/64170/7334/1540/3551/7314/257397/8767/23118/841/8517/5970/5027/7128/837/598/10454/6233/5600/6300/5608/4791/351/330/64127/3656/7189/3326/4210/7311/114548/1147/9447/596/6885/842/10392/10910/835/58484/7316/7335/22861/329 52 Human_herpesvirus_8_type_P R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 52/5323 55/10654 6.646880150301447e-13 3.596984758259283e-12 1.3266849854650258e-12 51807/10381/1780/3305/8655/84516/832/7846/113457/81027/3306/3312/51164/3303/79861/3337/10376/3301/10540/140735/84617/5241/11258/1783/10382/93661/10294/55860/830/7277/10671/1639/2908/347733/51143/3326/367/10383/84790/3304/7280/10728/829/1778/4306/1781/2289/10121/3320/10963/55466/2288 52 Human_herpesvirus_8_type_P R-HSA-9612973 Autophagy 97/5323 119/10654 7.212253695965314e-13 3.887795553460328e-12 1.4339454665439285e-12 9927/5563/2670/65018/1459/1915/9140/8878/1460/53632/84938/5116/115201/9474/8655/1457/3043/3920/10325/29082/9776/55054/55062/2475/84557/10670/3312/11315/64121/7314/64422/139341/25978/51160/60673/9821/51422/7249/10533/10013/79720/192111/440738/6714/8408/84971/123/55669/6233/9804/30849/51001/57521/140735/28956/7405/389541/79065/22863/58528/7416/26100/1068/64223/5571/128866/6009/3326/55004/7311/5562/11345/55626/7251/5564/5565/7248/11337/10452/8897/1080/64419/6035/153129/7316/83734/5289/8678/10226/8649/3320/81631/10542/23710/54543/7431/23192 97 Human_herpesvirus_8_type_P R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 55/5323 59/10654 7.239534008575734e-13 3.887795553460328e-12 1.4339454665439285e-12 6227/6206/1965/6234/6191/8668/6224/8662/26986/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1978/1968/6230/6194/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 55 Human_herpesvirus_8_type_P R-HSA-165159 mTOR signalling 40/5323 40/10654 8.19953056535001e-13 4.369977085396766e-12 1.6117897004455963e-12 5563/53632/6198/29904/10325/2475/55437/10670/92335/64121/51719/84335/51422/7249/1981/5494/1977/1978/57521/28956/6194/389541/58528/64223/5571/6794/6009/208/1975/55004/5562/5564/5565/7248/7529/207/153129/8649/10542/81617 40 Human_herpesvirus_8_type_P R-HSA-5674135 MAP2K and MAPK activation 40/5323 40/10654 8.19953056535001e-13 4.369977085396766e-12 1.6117897004455963e-12 4893/71/84292/5908/22866/5605/5037/2244/54756/3690/408/5894/8826/4140/3845/3265/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/28956/283455/3674/409/673/7450/60/7529/5595/5604/54518/10256/8649/5906 40 Human_herpesvirus_8_type_P R-HSA-180585 Vif-mediated degradation of APOBEC3G 51/5323 54/10654 1.2649363094072282e-12 6.716095801267812e-12 2.4771145999513946e-12 5689/5682/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/60489/5706/5714/5688/5687/5708/5704/7311/5694/5684/8065/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_herpesvirus_8_type_P R-HSA-167172 Transcription of the HIV genome 65/5323 73/10654 1.3294982600815003e-12 7.032346059904779e-12 2.593757982667906e-12 6884/6875/6874/5431/5435/5433/2960/8732/2965/5439/6873/6881/2967/51616/11198/904/51497/2959/404672/5438/83860/2068/1025/6883/7936/6829/2957/25920/2963/5434/5436/6878/4331/8148/2966/2962/54457/8812/905/2071/6880/6908/6882/2961/5432/22916/6877/6917/5440/902/5430/6749/5441/7469/4686/6872/6879/9150/2958/5437/6827/2968/138474/1022/8178 65 Human_herpesvirus_8_type_P R-HSA-72649 Translation initiation complex formation 54/5323 58/10654 1.358991197219101e-12 7.161425522424251e-12 2.6413666872817538e-12 6227/6206/1965/6234/6191/8668/6224/8662/26986/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1968/6230/6194/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 54 Human_herpesvirus_8_type_P R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 47/5323 49/10654 1.917039601604443e-12 1.0064457908423326e-11 3.7120994642222724e-12 9134/57060/2810/1869/6790/25904/1647/8900/55571/55835/57472/144455/85456/29883/1263/7027/7832/898/5934/890/10769/983/7157/5325/79733/1820/4869/4850/891/5111/246175/4848/23019/1874/1017/25946/4849/1027/9337/1026/5933/28984/2033/995/10498/581/3276 47 Human_herpesvirus_8_type_P R-HSA-9614085 FOXO-mediated transcription 59/5323 65/10654 2.092439138411031e-12 1.0944467909830189e-11 4.036675778660295e-12 2308/857/2290/65018/57060/2660/356/10971/7295/2810/84676/4089/1647/1387/4088/10628/4801/3630/56729/23411/7534/847/5934/3484/5443/8850/10000/3066/604/5105/7532/4303/23410/4287/4800/901/9314/10370/2908/6794/4852/6648/4087/208/25942/7529/27113/2309/10018/4802/207/1027/6720/1649/1026/2033/3065/91584/10891 59 Human_herpesvirus_8_type_P R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 43/5323 44/10654 2.2847685882742804e-12 1.1818637513609972e-11 4.359097964470668e-12 892/7321/8239/9612/4609/4089/22938/23327/4088/1030/904/7314/5054/7027/6497/51592/7323/6667/4092/7050/5494/6233/1025/4221/3726/1024/60436/8812/1874/142/905/4087/7311/64750/54778/7316/1875/9611/5933/3065/6498/25937/23439 43 Human_herpesvirus_8_type_P R-HSA-69231 Cyclin D associated events in G1 43/5323 44/10654 2.2847685882742804e-12 1.1818637513609972e-11 4.359097964470668e-12 8454/5925/1869/5753/1031/3717/5520/1032/28227/1030/5518/7314/5515/25/7027/5934/6714/5519/6502/595/896/6233/1163/1019/1029/4331/4067/1874/1870/7311/5516/894/902/1027/6500/7316/1875/1026/5933/1871/1021/1022/1028 43 Human_herpesvirus_8_type_P R-HSA-69236 G1 Phase 43/5323 44/10654 2.2847685882742804e-12 1.1818637513609972e-11 4.359097964470668e-12 8454/5925/1869/5753/1031/3717/5520/1032/28227/1030/5518/7314/5515/25/7027/5934/6714/5519/6502/595/896/6233/1163/1019/1029/4331/4067/1874/1870/7311/5516/894/902/1027/6500/7316/1875/1026/5933/1871/1021/1022/1028 43 Human_herpesvirus_8_type_P R-HSA-448424 Interleukin-17 signaling 64/5323 72/10654 2.3868510581201573e-12 1.2301463145696196e-11 4.537179763459563e-12 8454/3605/3725/9252/4790/1848/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/23118/8517/5528/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/1846/79155/64127/5602/3656/7189/7311/23765/6416/5595/5516/1147/1845/6885/5604/10392/6500/7316/7335/4205/466/23291/2002/5609/1385/5599 64 Human_herpesvirus_8_type_P R-HSA-169911 Regulation of Apoptosis 50/5323 53/10654 2.404544192825349e-12 1.2347422187245497e-11 4.5541309529884645e-12 5689/5682/4976/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Human_herpesvirus_8_type_P R-HSA-420499 Class C/3 (Metabotropic glutamate/pheromone receptors) 38/5323 38/10654 3.3087358490129194e-12 1.6867359925946294e-11 6.221231020455261e-12 50833/5726/2550/50832/259294/2912/259295/9568/2911/2914/259296/259289/50835/338398/2916/259293/54429/222545/80835/50840/2913/2918/50838/83756/259286/259287/50836/846/259290/80834/259292/50834/259285/2917/50831/50839/50837/2915 38 Human_herpesvirus_8_type_P R-HSA-5696394 DNA Damage Recognition in GG-NER 38/5323 38/10654 3.3087358490129194e-12 1.6867359925946294e-11 6.221231020455261e-12 10445/9978/10980/10987/7314/83444/86/1643/29844/10920/54891/6233/93973/8607/5886/8451/8450/1642/142/125476/1069/2873/7311/60/8533/10038/51138/7528/9318/7316/64708/283899/4798/79913/54617/5887/50813/7508 38 Human_herpesvirus_8_type_P R-HSA-983231 Factors involved in megakaryocyte development and platelet production 127/5323 168/10654 6.442294582072785e-12 3.2723135295943715e-11 1.206935675075768e-11 9927/3443/23764/64780/64837/11311/11127/51807/3798/10381/832/285643/3043/10112/64147/3717/7846/113457/81027/11004/10749/2626/4097/4778/7465/81930/5879/3445/25/113220/79861/5868/3797/23348/23186/5567/29127/55605/3444/5573/91768/3796/124602/3451/55614/3448/89953/56992/10376/3066/7157/3439/55669/3835/147700/3833/161882/221037/3452/9493/81704/3660/3446/9732/3831/84617/85440/9585/10382/5568/830/3832/7277/1793/23303/2623/3659/5566/26153/2627/1062/5889/146909/347733/3440/90990/4602/998/7975/5577/23046/10383/24137/60/25942/84790/84643/3456/1020/22920/10362/7280/829/55582/1017/23468/3441/2624/9371/8165/5575/23095/2625/3449/81928/3705/5576/547/3065/23028/3834/55083/3799/51317/5890/10938/221458 127 Human_herpesvirus_8_type_P R-HSA-176187 Activation of ATR in response to replication stress 37/5323 37/10654 6.64563914282447e-12 3.351402965574921e-11 1.2361064317722936e-11 5982/4174/84515/4998/10926/990/84126/55388/6117/5001/6118/23594/63967/993/5985/4175/5984/5884/5810/4999/4172/5000/8318/4173/6119/3364/144715/1111/23595/5983/4176/1017/5883/8317/545/4171/995 37 Human_herpesvirus_8_type_P R-HSA-6806003 Regulation of TP53 Expression and Degradation 37/5323 37/10654 6.64563914282447e-12 3.351402965574921e-11 1.2361064317722936e-11 11200/472/639/4194/8900/2475/5518/51230/7314/5515/6446/117584/890/983/5519/10000/900/7157/6233/7874/253260/5170/1029/80196/64223/1616/208/79109/7311/5516/1017/207/7316/55615/9099/5527/4193 37 Human_herpesvirus_8_type_P R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 67/5323 77/10654 6.97975749734032e-12 3.507328142413511e-11 1.2936167090935257e-11 1912/23165/7486/6045/80012/10274/348995/6613/57122/23511/1911/6672/23279/23225/165918/57332/5371/8924/672/9972/6612/8021/6117/55746/51564/51588/7518/10762/79902/9656/9883/84733/9063/6396/129401/7703/6015/8554/4928/5903/55706/7175/1029/8535/5885/641/493861/4927/8243/142/1069/8086/7329/648/5893/9631/79023/23636/10735/53371/6996/23137/9688/7341/9126/8480/7508 67 Human_herpesvirus_8_type_P R-HSA-5387390 Hh mutants abrogate ligand secretion 54/5323 59/10654 8.217399397923531e-12 4.114548381807263e-11 1.5175792857000568e-11 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/51009/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/9861/5698/5692/5713/5710/5719/6233/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 54 Human_herpesvirus_8_type_P R-HSA-3928662 EPHB-mediated forward signaling 41/5323 42/10654 8.813261316062631e-12 4.3662882646831416e-11 1.610429143372453e-11 71/1947/2051/10094/2050/2047/2534/9475/1948/8976/6093/8997/3265/5879/1072/10093/5921/6453/6714/7525/10109/64283/2904/5747/7074/1949/2049/10092/4067/998/2048/10097/387/60/5058/3984/3985/6383/10552/10096/10095 41 Human_herpesvirus_8_type_P R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 41/5323 42/10654 8.813261316062631e-12 4.3662882646831416e-11 1.610429143372453e-11 83990/5892/9156/1763/7486/5982/472/4683/84126/672/6117/83695/6118/5888/116028/7517/5985/5984/5884/5810/80010/7516/580/11073/641/6119/3364/10524/144715/5889/1111/79728/5983/5883/10111/675/545/10635/5932/7156/5890 41 Human_herpesvirus_8_type_P R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 41/5323 42/10654 8.813261316062631e-12 4.3662882646831416e-11 1.610429143372453e-11 2788/6000/2780/1459/2770/1460/2775/10576/1457/2782/10574/10693/2773/2787/10575/10681/8786/2792/2785/2783/2784/2771/2791/2781/2786/22948/9628/10694/54331/59345/8787/51764/94235/2779/7203/908/55970/346562/2793/6950/2790 41 Human_herpesvirus_8_type_P R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 36/5323 36/10654 1.334658528816156e-11 6.56595996518997e-11 2.421739619824678e-11 4893/71/5908/22866/5605/5037/2244/3690/408/5894/8826/4140/3845/3265/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/283455/3674/409/673/7450/60/7529/5595/5604/54518/10256/5906 36 Human_herpesvirus_8_type_P R-HSA-6804757 Regulation of TP53 Degradation 36/5323 36/10654 1.334658528816156e-11 6.56595996518997e-11 2.421739619824678e-11 11200/472/4194/8900/2475/5518/51230/7314/5515/6446/117584/890/983/5519/10000/900/7157/6233/7874/253260/5170/1029/80196/64223/1616/208/79109/7311/5516/1017/207/7316/55615/9099/5527/4193 36 Human_herpesvirus_8_type_P R-HSA-5693532 DNA Double-Strand Break Repair 125/5323 166/10654 1.5068015145210426e-11 7.387002546798282e-11 2.724566831684849e-11 2237/83990/151987/5892/9156/1763/7486/27343/5982/11200/472/6613/80198/3981/2140/64421/4683/165918/84126/8900/8924/2067/672/6117/7334/10714/348654/83695/55183/7314/6118/25/5888/322/51588/7518/51720/63967/5531/116028/2070/890/197342/9031/7517/9656/84464/5985/7157/5984/6233/7158/6047/5884/5810/5424/8467/80010/3838/7516/7515/54107/51567/580/11073/5591/5425/641/5111/6119/3364/22976/10524/5427/144715/5889/55775/5429/142/1111/9682/10721/7329/79728/51426/146956/7311/23030/3980/5536/5983/10038/2547/79840/56655/51750/1017/54962/5893/5883/10111/57804/7520/675/51548/545/7336/2072/29086/7316/8314/5426/10635/7341/8914/23514/5932/2138/9025/79184/7156/5890/5599/5981/2139 125 Human_herpesvirus_8_type_P R-HSA-72702 Ribosomal scanning and start codon recognition 53/5323 58/10654 1.514868631954628e-11 7.400764462361672e-11 2.7296426738071334e-11 6227/6206/1965/6234/6191/8668/6224/8662/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1968/6230/6194/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 53 Human_herpesvirus_8_type_P R-HSA-8848021 Signaling by PTK6 50/5323 54/10654 1.6649642735552174e-11 8.077947354800658e-11 2.979409752677758e-11 4893/1796/5770/2909/9021/27043/3091/2064/5753/145957/9542/9564/3845/3265/5829/7314/5879/120892/1839/2065/2069/898/202559/5921/6421/595/6233/1019/10657/1793/6774/2908/3084/10718/7311/2034/387/1956/63916/1017/685/207/55620/1027/7316/1950/867/2066/1398/9844 50 Human_herpesvirus_8_type_P R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 50/5323 54/10654 1.6649642735552174e-11 8.077947354800658e-11 2.979409752677758e-11 4893/1796/5770/2909/9021/27043/3091/2064/5753/145957/9542/9564/3845/3265/5829/7314/5879/120892/1839/2065/2069/898/202559/5921/6421/595/6233/1019/10657/1793/6774/2908/3084/10718/7311/2034/387/1956/63916/1017/685/207/55620/1027/7316/1950/867/2066/1398/9844 50 Human_herpesvirus_8_type_P R-HSA-373755 Semaphorin interactions 58/5323 65/10654 1.8200137590622193e-11 8.769723832193638e-11 3.2345594203953645e-11 5361/2909/388/2064/5788/8829/3688/54209/23365/79784/2534/9475/1808/8482/4628/6093/10507/5362/5062/5879/1400/23396/1072/7094/389/10371/2932/55558/64218/10570/80031/9723/23129/57556/10627/4233/5063/3326/387/5058/1020/4629/3984/4627/3985/1809/9037/971/10398/9826/4637/3320/91584/56896/103910/8851/6237/2242 58 Human_herpesvirus_8_type_P R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 58/5323 65/10654 1.8200137590622193e-11 8.769723832193638e-11 3.2345594203953645e-11 3725/4436/5892/472/5431/5435/5433/2965/5439/672/2967/1386/11198/904/51497/2176/404672/5438/1643/9656/2177/2068/7157/1025/2353/7936/6829/25920/2963/5434/5436/4292/4331/2966/2962/8812/905/1111/2071/55215/5432/6917/5440/8621/902/5430/6749/545/5441/7469/5395/9150/5437/51755/6827/2968/1022/8178 58 Human_herpesvirus_8_type_P R-HSA-5632684 Hedgehog 'on' state 72/5323 85/10654 1.8796797764676133e-11 9.026312100648232e-11 3.329197520382732e-11 5689/5682/11127/22873/1452/51684/143471/5705/8452/5709/9978/5695/5711/5683/408/5699/5702/83737/6469/5696/5691/7314/5718/5700/122706/5707/23198/2737/5727/8650/9861/8405/5698/5692/5713/5710/5719/6233/91653/409/79577/5706/5714/2736/5688/5687/5708/25989/5704/7311/5694/57154/5684/5720/2735/6608/5690/5717/9491/10197/64750/132884/7316/10213/50937/5715/5701/5685/5686/5716/5693/5721 72 Human_herpesvirus_8_type_P R-HSA-5678895 Defective CFTR causes cystic fibrosis 55/5323 61/10654 2.3185360470925067e-11 1.1095851082514138e-10 4.092510817102062e-11 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/51009/5696/5691/7314/5718/5700/122706/5707/10956/79139/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 55 Human_herpesvirus_8_type_P R-HSA-5658442 Regulation of RAS by GAPs 60/5323 68/10654 2.435591040100982e-11 1.16165308251596e-10 4.284554443424743e-11 5689/4893/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/3845/3265/4763/5696/5691/7314/5718/5700/122706/5707/23198/5921/9861/5698/5692/5713/5710/5719/6233/200734/9462/5706/84078/5714/5688/5687/5708/5704/7311/5694/5684/5720/153090/5690/5717/9491/10197/7316/10213/5715/8437/5701/5685/5686/5716/5693/5721 60 Human_herpesvirus_8_type_P R-HSA-5688426 Deubiquitination 204/5323 297/10654 2.6781669607752768e-11 1.2730340925036535e-10 4.6953638394815494e-11 5689/221937/5682/79594/7419/10474/7321/84196/4738/7375/9817/10445/91833/3091/143471/5705/11274/55031/8239/5709/5695/4792/4609/4194/4089/5711/7347/4088/5683/324/408/64135/5699/8312/5702/8900/8975/57599/377630/672/6881/51616/7187/7040/7345/3054/1540/80351/5696/5691/7314/5718/3607/90865/2648/5700/122706/5707/8737/83444/8767/171023/55611/51720/57646/23198/63967/8517/86/993/890/7417/80124/983/4092/2099/1643/9861/23586/81847/64426/8850/7128/29844/7046/6502/5698/9146/5692/5713/5710/10454/8473/7157/10869/9958/8313/5719/54891/6233/9804/55593/84282/93973/10318/23770/8607/7874/5886/10600/23326/93624/8237/4303/409/330/5706/4287/27005/7706/580/7416/5423/79155/25862/9738/8658/84132/5714/79589/55288/27430/64127/5688/9097/5687/8078/5708/125476/4087/63891/7189/5704/7048/7311/367/114548/387/60/5694/7528/9960/23358/23032/5684/8295/5720/10617/7186/56957/6885/991/51377/10392/5690/2625/57506/5717/9491/4086/1080/57695/10197/64750/29086/7316/10213/8314/55252/8678/9100/7415/5715/283899/5701/4798/329/79913/9099/5685/54617/5686/2033/5728/5716/79184/78990/5887/9736/5693/154/10254/5721/4193 204 Human_herpesvirus_8_type_P R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 211/5323 309/10654 2.8828803830843374e-11 1.3655738071808932e-10 5.036680409532641e-11 8454/5689/127544/11065/55070/5682/55819/8916/7321/9021/8697/9817/7174/143471/5705/9690/8452/5709/9978/5695/55236/54620/4734/7337/84676/7704/3093/5711/23327/51465/10616/5683/25898/5699/7328/7428/5702/22954/83737/51529/10075/29945/79176/8924/56658/51434/6468/10425/25793/51666/90293/54461/29882/7334/55182/4591/7332/5696/5691/9820/55658/7314/996/9354/5718/197131/8945/64410/51320/5700/122706/5707/10477/148581/23198/10533/51130/6477/7323/4008/84861/11059/26118/51433/9861/26249/55905/6502/5698/5692/5713/9903/26190/79654/5710/9040/7324/5719/64682/8925/51191/6233/26091/6047/868/127247/5930/26268/115290/51725/140459/23608/55585/64320/899/23352/26224/142678/246184/151636/11146/81559/144699/5706/79876/26263/8881/7317/80196/84078/5714/26272/8651/64219/5688/55336/5687/26270/63893/5708/55008/10422/90933/63891/9246/10393/5704/9870/9520/25847/51343/7311/9320/26232/57520/5694/997/7325/140691/57154/5684/6737/8065/5720/84708/7319/54850/26046/991/10273/7320/5690/5717/9491/6500/26259/10197/53339/7336/64750/51619/54778/7316/10213/7335/222235/25831/7322/5715/5701/23291/5685/5686/55521/55294/135892/8453/80176/8139/126433/26267/5716/55284/80204/27338/23014/90678/5693/5721/51676/642 211 Human_herpesvirus_8_type_P R-HSA-438064 Post NMDA receptor activation events 69/5323 81/10654 2.8922600891251328e-11 1.3655738071808932e-10 5.036680409532641e-11 5563/4893/51807/817/53632/10381/107/7846/113457/81027/6196/8874/6197/3845/3265/814/5879/5923/818/57554/79861/5567/5594/51422/5573/6714/10376/6195/5613/801/2891/805/5170/84617/3838/2904/2890/10382/5568/7277/10645/5566/84254/5571/27330/347733/3084/816/5577/5562/10383/84790/5564/5565/7280/5595/815/28964/5575/114/5576/2903/4137/2066/1742/88/1385/808/8536 69 Human_herpesvirus_8_type_P R-HSA-5675221 Negative regulation of MAPK pathway 39/5323 40/10654 3.390980729111567e-11 1.5956889250367809e-10 5.885419818524917e-11 4893/1844/1850/1848/5526/1852/5605/5037/5894/1847/5518/4140/3845/3265/7314/5515/8844/1849/5594/5528/5519/80824/6233/1843/369/1846/11221/673/8315/5529/7311/5536/7529/5595/5516/5604/5525/7316/5527 39 Human_herpesvirus_8_type_P R-HSA-190236 Signaling by FGFR 73/5323 87/10654 3.4856713522855946e-11 1.634779864221944e-10 6.029599918164205e-11 5295/4893/2250/5335/54845/5431/5435/5433/8569/9965/5439/2264/7072/2885/7073/5518/2252/3845/3265/7314/5515/5290/8823/5594/8074/2260/5438/3185/2249/6714/2248/4670/2247/6233/2246/2251/200734/5781/5725/2963/5434/6464/5436/673/2263/2962/6654/7311/2549/5432/22916/5595/5516/10253/5440/23543/5430/3178/8817/10817/5441/2254/4686/7316/152831/26281/10818/2261/867/5437/2255/27006/3187 73 Human_herpesvirus_8_type_P R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 38/5323 39/10654 6.644712044032223e-11 3.106016560117388e-10 1.1455999432445835e-10 83990/5892/9156/1763/7486/5982/472/4683/84126/672/6117/83695/6118/5888/116028/5985/5984/5884/5810/80010/7516/580/11073/641/6119/3364/10524/144715/5889/1111/5983/5883/10111/675/545/5932/7156/5890 38 Human_herpesvirus_8_type_P R-HSA-2408522 Selenoamino acid metabolism 93/5323 118/10654 8.115341617451818e-11 3.780889289985003e-10 1.394514959011414e-10 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6156/6143/6139/3921/6208/6170/7296/6203/6147/4143/191/6222/2936/6134/6155/6231/6142/9061/23521/6207/6233/51091/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/875/6164/79048/6209/11224/6165/6130/6204/6228/7965/6124/6189/6135/6201/6161/6133 93 Human_herpesvirus_8_type_P R-HSA-8951664 Neddylation 165/5323 234/10654 8.927945284207464e-11 4.1457488497953466e-10 1.5290870332167033e-10 8454/5689/5682/64344/80344/80067/55884/7321/9021/4738/9817/5929/3091/143471/5705/8452/5709/9978/5695/54620/7704/10980/5711/7347/5683/23113/5699/79269/10987/7428/5702/79176/6468/26094/25793/1154/51666/90293/54461/5696/5691/9820/7314/51514/5718/51397/54165/8945/64410/23363/23038/5700/122706/5707/23198/55827/51130/28991/332/7323/9306/4008/84861/79016/1643/26118/9861/26249/6502/90864/55832/5698/5692/10920/5713/9903/26190/10238/5710/9040/5719/6233/83987/8835/127247/54939/26268/115290/54951/51725/140459/10537/8451/899/26224/149951/5931/144699/5706/26263/8450/84078/5714/55527/26272/5688/55336/5687/26270/1161/5708/1642/5704/2873/7311/2034/8533/26232/51667/5694/51122/150684/51138/56929/9318/5684/8065/5720/11091/25879/54850/5690/5717/9491/6500/26259/10197/53339/7316/10213/64708/222235/54876/7322/5715/5701/23291/170622/5685/5686/55294/8453/80176/8139/126433/26043/26267/5716/80204/23014/8816/5693/5721/51676/50813 165 Human_herpesvirus_8_type_P R-HSA-5655253 Signaling by FGFR2 in disease 41/5323 43/10654 9.746640775157828e-11 4.511027490344429e-10 1.6638136780307511e-10 5295/4893/2250/5335/5431/5435/5433/5439/2885/2252/3845/3265/5290/8823/8074/5438/2249/2248/2247/2246/2251/2963/5434/5436/2263/2962/6654/2549/5432/22916/5440/5430/8817/5441/2254/4686/26281/10818/5437/2255/27006 41 Human_herpesvirus_8_type_P R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 47/5323 51/10654 1.0735884570034543e-10 4.90405610970374e-10 1.808775417711401e-10 6227/6206/1965/6234/6191/8668/6224/8662/6202/6218/3921/8665/6208/6203/8666/6222/8667/6231/8663/8894/6207/6233/51386/6188/1968/6230/6194/6232/6193/6210/6229/6205/6235/6223/8664/6187/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 47 Human_herpesvirus_8_type_P R-HSA-113418 Formation of the Early Elongation Complex 33/5323 33/10654 1.0804956602758773e-10 4.90405610970374e-10 1.808775417711401e-10 5431/5435/5433/2965/5439/2967/51497/404672/5438/2068/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/7469/4686/9150/5437/6827/2968/1022 33 Human_herpesvirus_8_type_P R-HSA-163359 Glucagon signaling in metabolic regulation 33/5323 33/10654 1.0804956602758773e-10 4.90405610970374e-10 1.808775417711401e-10 2788/107/2782/2787/5567/112/5573/111/2785/2783/2784/196883/115/2791/5568/2642/113/5566/2641/2786/5577/109/54331/5575/59345/51764/94235/114/108/55970/2778/5576/2790 33 Human_herpesvirus_8_type_P R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 33/5323 33/10654 1.0804956602758773e-10 4.90405610970374e-10 1.808775417711401e-10 5431/5435/5433/2965/5439/2967/51497/404672/5438/2068/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/7469/4686/9150/5437/6827/2968/1022 33 Human_herpesvirus_8_type_P R-HSA-68962 Activation of the pre-replicative complex 33/5323 33/10654 1.0804956602758773e-10 4.90405610970374e-10 1.808775417711401e-10 5422/4174/84515/4998/10926/990/55388/6117/5001/5558/6118/23594/5557/4175/23649/4999/4172/5000/8318/54107/4173/51053/6119/5427/81620/29935/23595/4176/56655/1017/8317/5426/4171 33 Human_herpesvirus_8_type_P R-HSA-9022692 Regulation of MECP2 expression and activity 33/5323 33/10654 1.0804956602758773e-10 4.90405610970374e-10 1.808775417711401e-10 2290/79718/817/9212/27327/28996/9612/6907/192669/4204/4343/814/818/3066/26523/801/805/3930/5566/816/25942/27161/815/8841/57690/192670/9611/2874/3064/3065/23112/1385/808 33 Human_herpesvirus_8_type_P R-HSA-5358346 Hedgehog ligand biogenesis 57/5323 65/10654 1.3626718137278914e-10 6.164885022235187e-10 2.273810134262483e-10 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/6868/51009/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/9861/5698/5692/5713/5710/5719/6233/5706/84447/5714/5688/5687/5708/5704/7311/147111/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721/5034 57 Human_herpesvirus_8_type_P R-HSA-1852241 Organelle biogenesis and maintenance 201/5323 296/10654 1.8401963460295233e-10 8.298577752767754e-10 3.06078542035275e-10 55763/5563/57728/79738/79867/55735/79718/7531/11190/203068/11127/54801/51807/1258/85302/79441/53632/10381/5116/3313/5048/10576/5469/22832/10989/60412/8655/83658/6010/9702/132320/1432/1387/7846/7840/113457/6907/11064/84902/81027/2847/11232/10499/23054/5518/1386/55835/85441/3054/23332/7019/93323/814/96764/79861/3797/10575/1454/112752/23408/51422/10013/54806/5465/91147/983/79959/5310/4208/6604/80205/8729/10376/10540/11336/117177/57545/26005/54930/54820/23322/6742/378/5600/1453/6300/801/9793/4218/140735/805/6102/84617/4899/5442/11258/22981/8636/54903/80776/79135/3418/7532/55125/10382/6753/23410/121441/7277/55112/26146/9814/4209/23354/2553/146057/9738/1639/55722/4957/5566/5571/2551/7283/347733/22919/27077/22994/4867/6648/1069/211/5577/10383/5347/403/84790/22948/80184/22897/5564/51106/23373/5565/22920/5108/261734/2746/57787/7280/10806/9657/1778/55770/23265/139322/115106/10694/22995/55559/8841/9371/10142/6608/10640/51134/95681/200186/7203/1781/80321/8766/9611/23409/79598/54205/149371/10121/347240/84131/6950/55212/3320/79600/10733/6256/4751/10498/80254/1385/26123/808/54536/9662/55142/8195/8648/8481/51259/55755/10891 201 Human_herpesvirus_8_type_P R-HSA-2426168 Activation of gene expression by SREBF (SREBP) 40/5323 42/10654 1.8689147255469554e-10 8.401159804615228e-10 3.0986210179742697e-10 79718/5469/6713/1387/6907/4801/6309/10499/23054/85441/7108/31/96764/4598/5465/2222/3157/6667/3156/6604/80205/10654/6721/9453/4800/57678/32/1595/4047/4802/6720/2194/4597/1717/6256/10498/2224/3422/4520/8648 40 Human_herpesvirus_8_type_P R-HSA-1227986 Signaling by ERBB2 46/5323 50/10654 1.991800249379627e-10 8.896707780562335e-10 3.281395231225251e-10 5295/4893/5335/26469/5578/2064/5753/145957/2534/4145/9542/2885/3845/3265/7314/1839/5290/2065/2069/6714/10000/6233/7525/5580/1729/6464/5782/3084/2886/208/6654/10718/7311/387/1956/2549/11140/8065/685/10273/207/7316/1950/3320/2066/5581 46 Human_herpesvirus_8_type_P R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 46/5323 50/10654 1.991800249379627e-10 8.896707780562335e-10 3.281395231225251e-10 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/2209/5706/5714/5688/5687/5708/5704/5694/5684/5720/5690/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721/4360 46 Human_herpesvirus_8_type_P R-HSA-392518 Signal amplification 32/5323 32/10654 2.169159875911994e-10 9.567423026357916e-10 3.528776831627168e-10 2788/64805/2770/2769/5028/1432/2782/2776/2773/2787/10681/2792/6714/2785/2783/2784/2771/2791/6915/2786/5321/54331/59345/51764/94235/55970/2767/346562/2793/9630/2790/10672 32 Human_herpesvirus_8_type_P R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 32/5323 32/10654 2.169159875911994e-10 9.567423026357916e-10 3.528776831627168e-10 2788/2149/2769/408/2768/2782/2776/2787/5594/10681/2792/6714/2785/2783/2784/2151/2791/2147/409/2786/5595/54331/59345/51764/94235/55970/2767/2793/9630/9002/2790/10672 32 Human_herpesvirus_8_type_P R-HSA-5673000 RAF activation 32/5323 32/10654 2.169159875911994e-10 9.567423026357916e-10 3.528776831627168e-10 4893/5526/817/5605/3717/4296/5894/5518/4140/3845/3265/5515/818/8844/5528/6714/5519/369/801/805/673/8315/5529/816/7529/5516/815/5604/5525/5527/808/5245 32 Human_herpesvirus_8_type_P R-HSA-69190 DNA strand elongation 32/5323 32/10654 2.169159875911994e-10 9.567423026357916e-10 3.528776831627168e-10 2237/1763/5982/5422/4174/84515/84296/6117/10714/5558/6118/64785/3978/5557/5985/4175/5984/23649/5424/4172/8318/4173/5425/5111/6119/51659/5983/4176/57804/9837/4171/5981 32 Human_herpesvirus_8_type_P R-HSA-5685938 HDR through Single Strand Annealing (SSA) 36/5323 37/10654 2.5458064652029814e-10 1.1193592801689358e-9 4.1285611425824675e-10 83990/9156/1763/7486/5982/472/4683/84126/2067/672/6117/83695/6118/25/5888/116028/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/5983/5893/5883/10111/545/2072/5932/7156 36 Human_herpesvirus_8_type_P R-HSA-390466 Chaperonin-mediated protein folding 77/5323 95/10654 2.9430044985695353e-10 1.289971130681413e-9 4.757833145744486e-10 2788/6000/2780/9134/1459/2770/51807/1460/10381/2775/10576/1457/7846/113457/2782/81027/10574/6468/54461/10693/8877/2773/2787/79861/10575/10681/898/8786/2792/26985/2785/10376/2783/26190/2784/10238/7157/2771/2791/5202/26224/84617/2629/2781/8237/10382/7277/6774/26272/26270/347733/55135/2786/10383/60/84790/22948/7280/9628/10694/8841/54331/22803/59345/8787/51764/94235/2779/7203/908/55970/346562/2793/6950/3801/55294/2790 77 Human_herpesvirus_8_type_P R-HSA-194315 Signaling by Rho GTPases 292/5323 455/10654 3.042356601893513e-10 1.3293775586534698e-9 4.90317687065545e-10 55839/11130/64837/71/6249/51517/5579/9735/7531/55789/5526/29/51807/2909/10811/10971/5578/9212/613/3798/1894/388/7533/2810/147841/147179/348995/54509/10381/57122/6280/1780/23122/3688/5048/57405/8655/10094/23279/5881/1432/2017/2491/7846/113457/23365/79784/9475/1060/171177/26230/9322/397/81027/4628/57449/11004/8976/1855/2885/23433/6093/9184/8997/8826/10499/5518/8874/23332/25909/3071/10726/81930/5062/55746/2665/5879/10395/5515/9181/85415/26999/25/79682/64333/1072/10403/79861/4638/25936/4659/10093/1856/10006/4771/389/5594/29127/3619/64105/89839/7534/332/5528/6453/9828/6714/55114/79902/3796/5519/81565/999/89953/396/10810/5880/85360/91687/11243/10376/57584/11113/58504/83540/7410/5580/7409/9055/1857/23191/7514/147700/54820/29984/1729/6396/1535/5600/25791/801/64946/9793/30849/10109/5586/140735/9886/2664/5500/10787/4221/805/3831/220134/5170/84617/4928/4688/5590/5903/9912/653361/55055/5747/80776/1783/401541/7204/2316/7532/3633/10382/7074/10627/79172/7277/10451/79980/58480/6232/5501/10152/6279/393/55288/54821/10092/9183/4650/10163/1062/699/347733/752/22919/55845/5063/3895/5529/51143/998/695/10788/286205/6654/10097/3817/57120/367/57381/10383/5347/387/6655/60/84790/84643/5058/7280/4629/7529/5595/1778/5516/5905/3984/54908/55143/1495/1499/5525/1058/991/79019/4627/10928/348235/80152/10458/1063/3985/54763/6722/8379/1027/9459/1080/23421/79023/55920/6242/1781/9824/10398/4085/5289/5585/5216/4168/10552/55166/9826/8936/4637/995/79003/391/23221/23028/89941/2/1742/90627/5527/4689/10096/7454/701/23380/9928/29941/3799/103910/57551/5296/5300/808/10095/1536/399/10672 292 Human_herpesvirus_8_type_P R-HSA-109606 Intrinsic Pathway for Apoptosis 48/5323 53/10654 3.1441089940580177e-10 1.36958555871196e-9 5.051477054165237e-10 7531/10971/7533/2810/1869/8655/836/90427/840/7159/637/578/23368/7027/5594/841/7534/4836/22900/598/10000/708/3002/7157/331/57099/317/140735/1029/572/7532/6774/5366/8626/208/7161/7529/5595/5533/27113/596/10018/842/207/54205/5534/581/5599 48 Human_herpesvirus_8_type_P R-HSA-5654743 Signaling by FGFR4 39/5323 41/10654 3.5793411479734597e-10 1.5543620355551412e-9 5.732992806858077e-10 5295/4893/5335/8569/9965/2264/2885/5518/3845/3265/7314/5515/5290/8823/5594/8074/2249/6714/2247/6233/2246/2251/5781/6464/673/6654/7311/2549/5595/5516/10253/8817/10817/2254/7316/152831/26281/10818/867 39 Human_herpesvirus_8_type_P R-HSA-4615885 SUMOylation of DNA replication proteins 42/5323 45/10654 3.917152864203248e-10 1.695825870748914e-9 6.254757447942353e-10 23165/9212/348995/6613/57122/23511/6790/23279/23225/9972/6612/8021/55746/7150/51588/3619/7153/332/10762/79902/9883/7155/6396/129401/4928/5903/55706/7175/5111/4927/8086/7329/5905/55143/9631/79023/23636/53371/9688/7341/10401/8480 42 Human_herpesvirus_8_type_P R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 31/5323 31/10654 4.354305623925388e-10 1.8735498510284464e-9 6.910261299195932e-10 3725/9252/1848/1432/6196/5518/1386/6197/51231/5515/5601/1849/5594/5528/9261/5519/5598/4208/6195/2353/5600/1846/5602/5595/5516/1845/4205/466/2002/1385/5599 31 Human_herpesvirus_8_type_P R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 31/5323 31/10654 4.354305623925388e-10 1.8735498510284464e-9 6.910261299195932e-10 857/7478/5526/1452/324/8312/1855/5518/5515/2535/1856/7471/5528/89780/5519/2932/8321/1857/4040/7479/7855/10023/4041/23401/5529/5516/1499/5525/139285/1455/5527 31 Human_herpesvirus_8_type_P R-HSA-168638 NOD1/2 Signaling Pathway 35/5323 36/10654 4.977307120209181e-10 2.13508265796778e-9 7.874879365414398e-10 834/1432/5603/83737/3654/64170/7334/1540/3551/7314/257397/8767/23118/841/8517/7128/837/10454/6233/5600/6300/5608/330/64127/3656/7189/7311/1147/6885/842/10392/835/7316/7335/329 35 Human_herpesvirus_8_type_P R-HSA-5617833 Cilium Assembly 143/5323 201/10654 5.972047673303501e-10 2.5540033666680925e-9 9.419995210169977e-10 55763/57728/79738/79867/7531/11190/203068/11127/54801/51807/1258/85302/79441/10381/5116/5048/10576/22832/60412/8655/83658/6010/9702/132320/7846/7840/113457/11064/84902/81027/2847/5518/55835/23332/93323/79861/3797/10575/1454/112752/10013/54806/91147/983/79959/5310/8729/10376/10540/11336/117177/57545/26005/54930/54820/23322/378/1453/9793/4218/140735/6102/84617/11258/22981/8636/54903/80776/7532/55125/10382/6753/121441/7277/55112/26146/9814/23354/146057/9738/1639/55722/4957/5566/7283/347733/22919/27077/22994/4867/1069/5577/10383/5347/403/84790/22948/80184/22897/22920/5108/261734/57787/7280/10806/9657/1778/55770/23265/115106/10694/22995/55559/9371/10142/6608/10640/51134/95681/7203/1781/80321/8766/79598/149371/10121/347240/84131/6950/55212/3320/79600/10733/4751/80254/26123/54536/9662/55142/8195/8481/51259/55755 143 Human_herpesvirus_8_type_P R-HSA-163685 Integration of energy metabolism 85/5323 108/10654 6.044433199660541e-10 2.577126518764358e-9 9.50528091685055e-10 2788/6804/5563/5331/2770/5578/2769/107/3767/2782/3630/2776/8826/5518/31/2181/6513/5515/2787/5567/1131/51422/10681/112/5573/5528/111/2792/5519/10554/51085/2785/2783/2784/2771/9370/7086/6844/2182/196883/115/2791/5568/2642/150/113/6616/5566/2864/32/23236/6794/2641/6514/2786/5577/6888/5207/5565/109/6812/5516/54331/5575/59345/51764/94235/114/4082/5330/3790/108/55970/2778/2194/2767/10768/152/2793/5576/948/47/5906/9630/2790 85 Human_herpesvirus_8_type_P R-HSA-451927 Interleukin-2 family signaling 41/5323 44/10654 7.356281438826131e-10 3.1175566218157727e-9 1.149856293386583e-9 5295/5777/1437/5291/6776/3558/3717/3563/2885/9846/3600/3965/3635/5290/1439/3718/3567/3932/6777/59067/3562/6464/6775/1438/6774/6850/6772/8503/3636/6654/3716/5293/2185/6655/3561/3578/3568/3560/5296/3559/3601 41 Human_herpesvirus_8_type_P R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 41/5323 44/10654 7.356281438826131e-10 3.1175566218157727e-9 1.149856293386583e-9 834/79370/55367/472/1387/51499/7159/637/27166/23368/332/64065/8797/7157/604/63970/839/317/5875/55240/5366/84883/147923/843/94241/8626/7161/10397/8795/665/27113/9540/8793/835/58484/3486/355/8794/124446/5876/581 41 Human_herpesvirus_8_type_P R-HSA-8986944 Transcriptional Regulation by MECP2 54/5323 62/10654 7.479338212029128e-10 3.1601888481456406e-9 1.1655804452443058e-9 627/2290/79718/5770/817/9212/27327/6657/28996/9612/4988/6907/192669/4204/3654/4343/6750/814/28514/818/6446/54487/4208/3066/26523/801/2891/805/2904/3930/54715/4233/5566/1392/816/25942/27161/815/8841/5468/4986/57690/192670/9611/2874/2289/5775/2903/3064/5728/3065/23112/1385/808 54 Human_herpesvirus_8_type_P R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF) 49/5323 55/10654 8.096774149342196e-10 3.4108267150073266e-9 1.258023843563096e-9 79718/10484/3638/5469/6713/1387/6907/4801/9632/6309/10499/23054/85441/7108/31/96764/4598/8720/5465/2222/3157/6667/3156/6604/80205/10654/6721/10802/9453/4800/57678/32/1595/5901/4047/9871/3837/4802/6720/2194/4597/1717/6256/10498/51360/2224/3422/4520/8648 49 Human_herpesvirus_8_type_P R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 30/5323 30/10654 8.739872085505984e-10 3.6598214358056307e-9 1.349861196163675e-9 56852/5982/9978/57599/6117/10714/7314/51514/6118/5985/5984/6233/5424/8451/54107/8450/5425/5111/6119/5427/1642/7311/5983/56655/57804/7320/7316/5426/7398/5981 30 Human_herpesvirus_8_type_P R-HSA-3928663 EPHA-mediated growth cone collapse 30/5323 30/10654 8.739872085505984e-10 3.6598214358056307e-9 1.349861196163675e-9 2042/2045/285220/79784/2534/9475/4628/6093/284656/2046/2041/6714/1943/2043/7525/1942/25791/10627/1945/4067/2044/387/4629/4627/10398/4637/1946/103910/1944/1969 30 Human_herpesvirus_8_type_P R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 46/5323 51/10654 1.0439348739240438e-9 4.358505541872788e-9 1.6075586220351514e-9 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/5718/1728/51582/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/5706/5714/5688/5687/5708/5704/5694/5684/5720/5690/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 46 Human_herpesvirus_8_type_P R-HSA-1236394 Signaling by ERBB4 51/5323 58/10654 1.0617287632164834e-9 4.419681567590509e-9 1.6301223303199202e-9 5295/4893/2670/51741/23385/6776/4734/10413/145957/83737/6868/9542/2885/3845/3265/7314/6387/1839/5290/6678/2065/2069/23118/348/11059/6714/2099/5664/1447/2567/3925/6233/5663/6464/5241/3084/6654/83464/10718/7311/1956/55851/51107/685/7316/1950/9611/2066/6285/1742/11033 51 Human_herpesvirus_8_type_P R-HSA-168325 Viral Messenger RNA Synthesis 40/5323 43/10654 1.379225669929593e-9 5.724396807052912e-9 2.11134375182515e-9 23165/348995/57122/5431/23511/5435/5433/23279/23225/5439/9972/8021/55746/5438/10762/79902/9883/6396/129401/4928/2963/5434/5903/55706/7175/5436/4927/2962/8086/5432/5440/9631/5430/79023/5441/23636/53371/9688/5437/8480 40 Human_herpesvirus_8_type_P R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK 29/5323 29/10654 1.7540827523328533e-9 7.258807154506838e-9 2.6772842009290923e-9 5563/53632/10325/2475/55437/10670/92335/64121/51719/51422/7249/5494/57521/28956/389541/58528/64223/5571/6794/6009/55004/5562/5564/5565/7248/153129/8649/10542/81617 29 Human_herpesvirus_8_type_P R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 33/5323 34/10654 1.8977495758450687e-9 7.830303968369535e-9 2.8880708161494646e-9 7321/9140/9474/3093/64135/83737/7187/1540/7314/29110/9636/8887/7323/23586/7128/3661/51191/6233/55593/84282/54476/7706/9246/7311/79671/5094/9641/57506/84166/7316/7322/54941/5300 33 Human_herpesvirus_8_type_P R-HSA-400253 Circadian Clock 59/5323 70/10654 1.9333591508757772e-9 7.953907383866135e-9 2.9336597764904842e-9 8454/79718/5936/3091/5469/1387/150094/6907/2155/5499/10499/23054/1386/9575/23411/85441/7314/96764/5054/8945/1454/5465/4208/6604/80205/56938/6233/8864/1453/5500/26224/10743/1374/1407/406/4209/5501/8553/2908/1390/7311/23373/8841/8204/4862/6500/200186/1408/6720/7316/9611/2033/79365/6256/10498/1385/8648/551/10891 59 Human_herpesvirus_8_type_P R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 39/5323 42/10654 2.5814884639518323e-9 1.0589371046006496e-8 3.90570450430644e-9 23165/348995/57122/23511/81608/23279/23225/9972/8021/55746/53981/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/7884/4927/10898/10482/51692/8086/22916/9631/29894/79023/23636/4686/8189/53371/9688/10189/8480/55339 39 Human_herpesvirus_8_type_P R-HSA-2428924 IGF1R signaling cascade 47/5323 53/10654 2.6028788660405413e-9 1.0646077222439074e-8 3.9266195867747466e-9 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/3845/3265/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/8471/2246/2251/5781/30849/5170/6464/2322/2263/3481/208/6654/2549/3480/8817/2254/152831/5289/26281/10818/2261/2255/27006/3479/5296 47 Human_herpesvirus_8_type_P R-HSA-202040 G-protein activation 28/5323 28/10654 3.520091279752387e-9 1.4314359626045112e-8 5.279601463090743e-9 2788/2780/2770/2775/4988/2782/2773/2787/10681/5443/2792/2785/2783/2784/2771/2791/2781/2786/54331/59345/51764/94235/2779/5173/55970/346562/2793/2790 28 Human_herpesvirus_8_type_P R-HSA-350054 Notch-HLH transcription pathway 28/5323 28/10654 3.520091279752387e-9 1.4314359626045112e-8 5.279601463090743e-9 79718/9759/9612/22938/1387/6907/4853/9794/79885/2648/9734/55869/51564/55534/84441/10013/83933/4854/8850/3066/10046/10014/4855/4851/8841/9611/3065/3516 28 Human_herpesvirus_8_type_P R-HSA-2559585 Oncogene Induced Senescence 32/5323 33/10654 3.7006414776267983e-9 1.496207631902559e-8 5.5185004490925945e-9 2077/27327/5925/2114/1869/4194/1031/192669/1032/1030/4343/7314/7027/5594/6667/7157/6233/26523/1019/1029/1870/7311/3397/2113/5595/57690/192670/7316/1871/1021/23112/4193 32 Human_herpesvirus_8_type_P R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 32/5323 33/10654 3.7006414776267983e-9 1.496207631902559e-8 5.5185004490925945e-9 4790/4792/177/3654/7334/3551/7314/257397/6283/8767/28512/23118/8517/5970/10454/6233/4791/351/64127/3656/7189/7311/28511/1147/6885/10392/7316/7335/4793/3146/6288/6285 32 Human_herpesvirus_8_type_P R-HSA-380108 Chemokine receptors bind chemokines 51/5323 59/10654 4.019831341383218e-9 1.620602492070541e-8 5.977309157900548e-9 729230/7852/1237/3576/6360/2920/2921/1236/6370/58191/1524/643/2833/6347/6387/10663/3579/6375/6846/2826/6376/3627/6346/51554/2829/1233/6366/6373/6357/10803/6351/3577/10563/10850/5473/4283/6356/56477/1234/57007/1238/6374/1230/2919/5196/6352/6348/6364/6372/6363/1232 51 Human_herpesvirus_8_type_P R-HSA-8939211 ESR-mediated signaling 154/5323 223/10654 4.122200056974132e-9 1.657124422903601e-8 6.1120139190623994e-9 5295/2788/374/3725/4893/857/7764/7031/2770/27327/10274/5431/5435/5433/1509/5469/1105/4609/1387/8312/2782/5439/192669/10499/1386/4343/3845/904/7392/3265/8877/2773/2787/6387/1839/5290/4316/5594/2069/10681/51523/5481/5438/4313/865/1655/6667/2792/6714/2099/2494/8850/10000/2785/595/2783/2784/2771/7514/1025/2353/26523/801/2791/2957/805/5170/2963/3838/5434/5590/6464/7090/5241/5747/5436/1903/3315/4318/5885/57678/7033/2962/8503/10524/8243/4602/2786/208/3326/23030/6908/1956/5536/3169/858/5432/3480/10728/5595/7528/3727/27161/2354/596/5440/685/54331/4435/2309/9687/59345/8204/5430/207/5451/2625/57690/6722/1027/51764/94235/5441/10735/192670/2100/1950/55970/4314/346562/2289/7391/2958/5437/2793/3320/2033/4846/9126/3065/2002/2066/861/23028/23112/10498/1385/5296/808/3276/8202/8648/2288/2790 154 Human_herpesvirus_8_type_P R-HSA-2428928 IRS-related events triggered by IGF1R 46/5323 52/10654 4.650734531421812e-9 1.8642687993477178e-8 6.876029761556316e-9 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/3845/3265/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/8471/2246/2251/5781/30849/5170/2322/2263/3481/208/6654/2549/3480/8817/2254/152831/5289/26281/10818/2261/2255/27006/3479/5296 46 Human_herpesvirus_8_type_P R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 38/5323 41/10654 4.823134172995342e-9 1.9278834606262628e-8 7.110661325618134e-9 23165/348995/57122/23511/81608/23279/23225/9972/8021/55746/53981/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10898/10482/51692/8086/22916/9631/29894/79023/23636/4686/8189/53371/9688/10189/8480/55339 38 Human_herpesvirus_8_type_P R-HSA-418597 G alpha (z) signalling events 43/5323 48/10654 6.216878708816884e-9 2.4779457063187976e-8 9.139469817941628e-9 2788/5579/2770/5578/5582/5583/107/2782/2773/2787/10681/112/111/2792/5588/2785/2783/2784/2771/5580/196883/115/2791/2781/150/113/10287/2786/109/151/54331/59345/51764/94235/114/108/55970/2778/346562/152/2793/5581/2790 43 Human_herpesvirus_8_type_P R-HSA-912526 Interleukin receptor SHC signaling 27/5323 27/10654 7.063446002630025e-9 2.8074204874860014e-8 1.0354679986014281e-8 5295/5777/1437/5291/3558/3717/3563/2885/9846/3635/5290/1439/3718/3567/3562/6464/1438/8503/3636/6654/3716/5293/3561/3568/3560/5296/3559 27 Human_herpesvirus_8_type_P R-HSA-1251985 Nuclear signaling by ERBB4 31/5323 32/10654 7.2093823812340145e-9 2.849326126515803e-8 1.050924161427667e-8 2670/51741/23385/6776/10413/145957/6868/9542/6387/1839/6678/2069/23118/348/6714/2099/5664/1447/3925/5663/5241/3084/83464/10718/55851/51107/685/9611/2066/6285/11033 31 Human_herpesvirus_8_type_P R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 31/5323 32/10654 7.2093823812340145e-9 2.849326126515803e-8 1.050924161427667e-8 892/4609/4089/22938/4088/1030/904/7314/5054/7027/6667/4092/7050/6233/1025/4221/3726/1024/60436/8812/1874/905/4087/7311/54778/7316/1875/5933/3065/25937/23439 31 Human_herpesvirus_8_type_P R-HSA-5654741 Signaling by FGFR3 37/5323 40/10654 8.994494621594036e-9 3.544889056745885e-8 1.307470396121439e-8 5295/4893/2250/5335/8569/2885/5518/3845/3265/7314/5515/5290/8823/5594/8074/2249/6714/2247/6233/2246/5781/6464/673/6654/7311/2549/5595/5516/10253/8817/10817/2254/7316/26281/10818/2261/867 37 Human_herpesvirus_8_type_P R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 79/5323 102/10654 9.42695036459331e-9 3.694629293309968e-8 1.362699466278992e-8 8454/7124/5689/5682/356/143471/5705/10673/5709/5695/7292/7133/5711/5683/5699/5702/7187/958/5696/5691/939/7314/5718/8945/23495/8744/5700/122706/5707/23198/8764/9020/8741/1896/9861/5698/5692/5713/5710/8718/9040/5719/6233/4791/959/8600/330/5706/5714/5688/5687/608/5708/5704/7311/5971/5694/1147/5684/5720/7186/5690/5717/9491/6500/10197/7316/10213/970/5715/7132/5701/329/23291/5685/5686/5716/5693/5721 79 Human_herpesvirus_8_type_P R-HSA-5689603 UCH proteinases 79/5323 102/10654 9.42695036459331e-9 3.694629293309968e-8 1.362699466278992e-8 5689/221937/5682/4738/10445/143471/5705/5709/5695/5711/7347/5683/5699/5702/7040/7345/3054/5696/5691/7314/5718/3607/5700/122706/5707/83444/171023/23198/86/4092/9861/29844/7046/5698/5692/5713/5710/8473/9958/5719/54891/6233/93973/8607/5706/580/5714/5688/5687/5708/125476/5704/7048/7311/60/5694/7528/5684/5720/51377/5690/5717/9491/10197/7316/10213/8314/55252/5715/283899/5701/4798/79913/5685/54617/5686/5716/5693/5721 79 Human_herpesvirus_8_type_P R-HSA-112043 PLC beta mediated events 47/5323 54/10654 1.0321103836050227e-8 4.011545054509025e-8 1.4795883079885905e-8 2780/5331/2770/817/5578/5582/2775/107/814/2773/818/5567/5594/112/5573/111/5613/2771/5332/5580/196883/115/801/805/3838/2781/5568/113/10645/5566/84254/23236/816/5577/109/815/5321/5575/114/5330/108/2779/10768/346562/5576/1385/808 47 Human_herpesvirus_8_type_P R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 47/5323 54/10654 1.0321103836050227e-8 4.011545054509025e-8 1.4795883079885905e-8 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/3845/3265/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/8471/2246/2251/5781/30849/5170/6464/2322/2263/3481/208/6654/2549/3480/8817/2254/152831/5289/26281/10818/2261/2255/27006/3479/5296 47 Human_herpesvirus_8_type_P R-HSA-74751 Insulin receptor signalling cascade 47/5323 54/10654 1.0321103836050227e-8 4.011545054509025e-8 1.4795883079885905e-8 5295/3643/4893/2250/5291/9965/2264/3630/2885/8660/9846/2252/3845/3265/54106/5290/3667/8823/5594/8074/57761/2260/2249/2248/2247/2246/2251/5781/30849/5170/6464/2322/2263/208/6654/2549/5595/8817/2254/152831/5289/26281/10818/2261/2255/27006/5296 47 Human_herpesvirus_8_type_P R-HSA-437239 Recycling pathway of L1 42/5323 47/10654 1.1217443472835474e-8 4.347918172528791e-8 1.6036536558236595e-8 9252/71/7430/51807/1785/10381/285643/7846/113457/1808/81027/6456/163/6196/1759/6197/8986/161/79861/5594/8650/6714/10376/6195/1213/1211/1175/1173/84617/10382/7277/4478/160/26052/27330/347733/3897/10383/24137/60/84790/7280 42 Human_herpesvirus_8_type_P R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 39/5323 43/10654 1.4303550705668542e-8 5.528872484306494e-8 2.039228021369171e-8 2788/107/2782/2787/22841/5567/10681/112/5573/111/2792/2785/2783/2784/196883/115/2791/5568/359/113/5566/2786/5577/109/54331/5575/59345/51764/94235/114/108/8766/55970/2778/2793/5576/4645/551/2790 39 Human_herpesvirus_8_type_P R-HSA-391251 Protein folding 78/5323 101/10654 1.4760984518427462e-8 5.690056223952723e-8 2.0986778277100906e-8 2788/6000/2780/9134/1459/2770/51807/1460/10381/2775/10576/1457/7846/113457/2782/81027/10574/6468/54461/10693/8877/2773/2787/79861/10575/10681/898/8786/2792/26985/2785/10376/2783/26190/2784/10238/7157/2771/2791/5202/26224/84617/2629/2781/8237/10382/7277/6774/26272/26270/347733/55135/2786/10383/60/84790/22948/7280/9628/10694/8841/54331/22803/59345/8787/51764/94235/2779/7203/908/55970/346562/1155/2793/6950/3801/55294/2790 78 Human_herpesvirus_8_type_P R-HSA-195721 Signaling by WNT 215/5323 331/10654 1.6500820939977054e-8 6.343348377745278e-8 2.3396332250240694e-8 2788/8454/56998/27123/9070/5689/2780/5158/857/7478/5579/5682/5331/1459/5526/1452/5578/1212/5929/5582/27327/1460/55737/143471/5705/6657/2775/8452/5530/55366/5709/9978/5695/1457/4609/5881/5711/1387/5683/324/5699/8312/2782/5702/192669/57216/1855/6932/90780/163/5518/4343/5593/25776/3845/6659/80351/5696/5691/4920/7314/5879/5515/2787/5718/51176/8945/2535/161/6662/51701/5700/122706/5707/1856/7473/1454/8322/23198/10681/7471/7534/5528/7091/89780/51699/83439/8323/2792/9861/81847/5519/2932/8321/7481/5698/5880/5692/5713/2785/2783/2784/5710/8313/5719/6233/7474/1857/7514/4040/7479/1213/1211/7855/7089/331/8607/1175/26523/801/2791/7976/4221/805/123169/5145/1173/7090/6597/864/4772/10023/4041/409/79577/6736/5706/160/23401/8658/5714/6934/10524/5688/5687/5148/23236/5708/5529/7088/2786/208/57680/5704/7311/387/5694/55553/5516/57154/27161/815/5684/8295/5720/7472/54331/7015/6885/1487/1499/5525/59345/139285/207/8085/5690/5532/57690/5717/9491/50855/6500/51764/94235/5330/10197/192670/64750/7316/10213/55970/5216/5715/5701/2793/1455/5685/5686/2033/54894/5534/3065/23112/23513/5527/1488/5716/23072/808/9736/5693/5721/6259/2790 215 Human_herpesvirus_8_type_P R-HSA-157118 Signaling by NOTCH 159/5323 235/10654 2.1889600410527056e-8 8.39200756883149e-8 3.095245375703382e-8 8454/5689/3725/79718/5682/892/4904/182/27327/3091/23385/5705/5709/9978/1869/5695/9759/9612/4609/11060/22938/5711/1387/4088/6907/5683/408/5699/6400/4853/5702/192669/83737/6868/9794/57534/4343/9787/388585/5696/5691/28514/7314/5718/23286/79885/2648/9734/7027/55869/5700/5707/51564/55534/3280/84441/10013/7534/83933/4854/3714/7091/8650/102/5664/9861/5870/8850/5087/2173/5698/5692/5713/595/5710/3002/3066/7157/5719/6233/2324/7089/26523/5663/10959/1999/23129/4242/7090/142678/23220/171558/409/5706/10460/10046/1024/5714/6772/10014/489/5688/5687/5708/59/26508/9148/4855/7088/5704/83464/23493/7311/1956/55851/51107/5694/4851/27161/5684/8841/2208/5720/5584/23462/207/5690/57690/5717/9491/6500/51548/3955/10197/192670/488/7316/10213/1950/9611/54492/1871/5715/5701/5685/5686/2033/55294/3065/861/2683/23112/5716/1385/1840/54567/3516/5693/5721 159 Human_herpesvirus_8_type_P R-HSA-168253 Host Interactions with Influenza Factors 38/5323 42/10654 2.6118768408908735e-8 9.986170421558312e-8 3.683224492446226e-8 3839/23165/348995/57122/23511/23279/23225/3836/9972/8021/7040/55746/402569/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/293/4927/10898/3840/8086/3837/9631/79023/23636/53371/9688/8480 38 Human_herpesvirus_8_type_P R-HSA-114452 Activation of BH3-only proteins 29/5323 30/10654 2.7276853522018173e-8 1.0344618033821986e-7 3.815431631821524e-8 7531/10971/7533/2810/1869/8655/90427/7159/637/23368/7027/7534/10000/7157/140735/572/7532/5366/8626/208/7161/7529/5533/27113/596/10018/207/5534/5599 29 Human_herpesvirus_8_type_P R-HSA-180786 Extension of Telomeres 29/5323 30/10654 2.7276853522018173e-8 1.0344618033821986e-7 3.815431631821524e-8 2237/1763/5982/5422/6117/10714/5558/6118/3978/5557/5985/5984/23649/8607/5424/54107/5425/5111/6119/5427/55135/5983/56655/7015/57804/10856/5426/1736/5981 29 Human_herpesvirus_8_type_P R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 29/5323 30/10654 2.7276853522018173e-8 1.0344618033821986e-7 3.815431631821524e-8 7124/7375/10616/1540/3551/7314/257397/81858/8737/55072/23118/8517/7128/10454/6233/331/8717/330/27005/7311/1147/7186/56957/6885/7316/7132/329/9099/7185 29 Human_herpesvirus_8_type_P R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 25/5323 25/10654 2.8432736182302126e-8 1.0611368649469255e-7 3.913817936025394e-8 11065/7321/8697/51529/29945/51434/9184/29882/7314/996/51433/119504/7324/64682/6233/246184/8881/10393/7311/25906/991/7316/4085/4751/701 25 Human_herpesvirus_8_type_P R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 25/5323 25/10654 2.8432736182302126e-8 1.0611368649469255e-7 3.913817936025394e-8 9252/1848/1432/6196/5518/6197/51231/5515/1849/5594/5528/9261/5519/5598/4208/6195/5600/1846/5595/5516/1845/4205/466/2002/1385 25 Human_herpesvirus_8_type_P R-HSA-418592 ADP signalling through P2Y purinoceptor 1 25/5323 25/10654 2.8432736182302126e-8 1.0611368649469255e-7 3.913817936025394e-8 2788/2769/5028/1432/2782/2776/2787/10681/2792/6714/2785/2783/2784/2791/2786/5321/54331/59345/51764/94235/55970/2767/2793/9630/2790 25 Human_herpesvirus_8_type_P R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 25/5323 25/10654 2.8432736182302126e-8 1.0611368649469255e-7 3.913817936025394e-8 2308/2475/84335/7249/2932/10000/2931/253260/5170/572/4303/6199/64223/208/79109/1147/2309/842/207/1027/1026/55615/3164/1385/4193 25 Human_herpesvirus_8_type_P R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 25/5323 25/10654 2.8432736182302126e-8 1.0611368649469255e-7 3.913817936025394e-8 5982/6117/10714/7314/6118/3978/5985/5984/6233/5424/7515/54107/5425/5111/6119/5427/51426/7311/3980/5983/56655/57804/7316/5426/5981 25 Human_herpesvirus_8_type_P R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus 25/5323 25/10654 2.8432736182302126e-8 1.0611368649469255e-7 3.913817936025394e-8 4904/182/23385/11060/57534/28514/7314/4854/3714/102/5664/6233/5663/142678/10460/9148/83464/7311/1956/55851/51107/7316/1950/54492/54567 25 Human_herpesvirus_8_type_P R-HSA-948021 Transport to the Golgi and subsequent modification 129/5323 185/10654 3.0133274498014924e-8 1.1216274396483333e-7 4.136926852553985e-8 6811/23256/374/6711/11014/2153/51807/10484/5861/10381/1780/9570/90411/8655/84516/832/3998/55738/7846/113457/51226/9382/375056/9632/3630/81027/6709/10652/54732/51272/51164/58485/79861/9117/4253/2801/377/10466/2517/22872/1315/81562/8615/55014/11316/91949/8729/23423/10376/1314/10540/83696/6399/378/6396/26286/1453/26958/140735/10959/84364/22820/84617/22796/11258/6712/2890/1783/10382/10802/93661/55860/2157/830/7277/10671/9554/966/11196/1639/10282/8775/81876/11015/347733/51143/51693/23243/5537/9871/10383/84790/10945/1075/7280/829/1778/9919/10113/25839/55291/51014/26984/83548/63908/1604/1781/57731/10121/2804/9527/57511/22870/64377/5265/8774/10972/381/4905/11320/2683/9276/287/375/84342/64689/288/22818/372 129 Human_herpesvirus_8_type_P R-HSA-3232142 SUMOylation of ubiquitinylation proteins 35/5323 38/10654 3.109413303914587e-8 1.1482794012094027e-7 4.235227956430147e-8 23165/348995/57122/23511/23279/23225/7428/5371/9972/8021/55746/51588/10762/79902/9883/9063/6396/129401/8554/4928/5903/55706/7175/4927/8086/7329/9631/79023/23636/53371/9688/7341/5987/8480/4193 35 Human_herpesvirus_8_type_P R-HSA-5655302 Signaling by FGFR1 in disease 35/5323 38/10654 3.109413303914587e-8 1.1482794012094027e-7 4.235227956430147e-8 5295/4893/11052/2250/5335/9530/613/6776/11064/2885/9846/3845/3265/7750/8805/26127/5290/8074/2260/2249/399687/2247/2246/2251/6777/1523/9208/6774/6772/6654/11160/2549/2254/26281/10818 35 Human_herpesvirus_8_type_P R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 35/5323 38/10654 3.109413303914587e-8 1.1482794012094027e-7 4.235227956430147e-8 1912/1459/6045/80012/1460/28996/1457/1911/6603/10138/57332/57492/196528/86/865/51412/84733/6604/8289/6602/23429/55193/6015/6595/6597/8535/6599/648/6601/23466/6598/2033/84333/6605/861 35 Human_herpesvirus_8_type_P R-HSA-2980766 Nuclear Envelope Breakdown 45/5323 52/10654 3.168269537051488e-8 1.1669516331495926e-7 4.304097221731562e-8 23165/5579/91754/5578/348995/57122/23511/23279/23225/9663/4001/9972/8021/55746/10762/983/79902/9883/7444/2010/64900/23175/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/5347/7112/4000/9631/140609/79023/23636/7443/53371/9688/8815/23592/8480 45 Human_herpesvirus_8_type_P R-HSA-5654727 Negative regulation of FGFR2 signaling 32/5323 34/10654 3.2546911906134395e-8 1.1956528734185666e-7 4.4099567320940653e-8 2250/8569/2885/5518/2252/7314/5515/8823/5594/8074/2249/6714/2248/2247/6233/2246/2251/5781/673/2263/7311/5595/5516/10253/8817/2254/7316/26281/10818/867/2255/27006 32 Human_herpesvirus_8_type_P R-HSA-3899300 SUMOylation of transcription cofactors 40/5323 45/10654 3.6250928910625165e-8 1.3282566921158752e-7 4.899042750257185e-8 1912/6045/80012/6613/28996/9612/1911/9994/1387/57332/4152/115426/10499/6612/11315/3622/51588/1655/84733/10155/9063/7703/6015/8554/8535/4869/10210/10521/1616/7329/25942/648/1487/8204/7341/10401/2033/6294/8648/10891 40 Human_herpesvirus_8_type_P R-HSA-112040 G-protein mediated events 47/5323 55/10654 3.648807088767601e-8 1.3334731360768868e-7 4.9182826924468284e-8 2780/5331/2770/817/5578/5582/2775/107/814/2773/818/5567/5594/112/5573/111/5613/2771/5332/5580/196883/115/801/805/3838/2781/5568/113/10645/5566/84254/23236/816/5577/109/815/5321/5575/114/5330/108/2779/10768/346562/5576/1385/808 47 Human_herpesvirus_8_type_P R-HSA-112382 Formation of RNA Pol II elongation complex 51/5323 61/10654 4.3128479435269616e-8 1.568004407375306e-7 5.7833103118694206e-8 5431/5435/5433/2965/5439/2967/11198/904/51497/4300/80349/404672/5438/2068/1025/23168/7936/6829/123169/25920/2963/5434/5436/9646/79577/4331/2966/2962/8812/905/2071/27125/5432/22916/55840/6917/5440/902/6830/5430/6749/5441/7469/4686/9150/54623/5437/6827/2968/1022/8178 51 Human_herpesvirus_8_type_P R-HSA-75955 RNA Polymerase II Transcription Elongation 51/5323 61/10654 4.3128479435269616e-8 1.568004407375306e-7 5.7833103118694206e-8 5431/5435/5433/2965/5439/2967/11198/904/51497/4300/80349/404672/5438/2068/1025/23168/7936/6829/123169/25920/2963/5434/5436/9646/79577/4331/2966/2962/8812/905/2071/27125/5432/22916/55840/6917/5440/902/6830/5430/6749/5441/7469/4686/9150/54623/5437/6827/2968/1022/8178 51 Human_herpesvirus_8_type_P R-HSA-442755 Activation of NMDA receptors and postsynaptic events 72/5323 93/10654 4.4180446727767266e-8 1.6021105295352718e-7 5.909104784804467e-8 5563/4893/51807/817/53632/10381/107/7846/113457/81027/6196/8874/6197/3845/3265/814/5879/5923/818/57554/79861/5567/5594/51422/5573/6714/22843/10376/6195/5613/801/2891/805/5170/84617/3838/8573/2904/2890/10382/5568/7277/10645/5566/84254/5571/27330/347733/3084/816/5577/5562/10383/84790/5564/5565/7280/5595/815/28964/5575/114/5576/2903/4137/2066/9647/1742/88/1385/808/8536 72 Human_herpesvirus_8_type_P R-HSA-112399 IRS-mediated signalling 42/5323 48/10654 4.6221396820965384e-8 1.667525777617905e-7 6.150377498714153e-8 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/3845/3265/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/2246/2251/5781/30849/5170/2322/2263/208/6654/2549/8817/2254/152831/5289/26281/10818/2261/2255/27006/5296 42 Human_herpesvirus_8_type_P R-HSA-73893 DNA Damage Bypass 42/5323 48/10654 4.6221396820965384e-8 1.667525777617905e-7 6.150377498714153e-8 56852/5982/9978/25898/57599/6117/10714/55666/7314/51514/6118/9636/11201/51455/5985/5984/6233/5424/8451/54107/7706/8450/5425/5111/6119/83932/5427/1642/5429/9246/51426/7311/5983/56655/57804/7320/7316/5426/9100/7415/7398/5981 42 Human_herpesvirus_8_type_P R-HSA-5218920 VEGFR2 mediated vascular permeability 28/5323 29/10654 5.2968330047499584e-8 1.90118470349061e-7 7.012187624440736e-8 857/2475/5062/5879/57761/1500/10000/3728/7410/7409/801/253260/805/5170/10451/64223/1003/5063/208/79109/5058/1495/1499/207/55615/3320/4846/808 28 Human_herpesvirus_8_type_P R-HSA-72086 mRNA Capping 28/5323 29/10654 5.2968330047499584e-8 1.90118470349061e-7 7.012187624440736e-8 5431/5435/5433/8732/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/4686/5437/2968/1022 28 Human_herpesvirus_8_type_P R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 24/5323 24/10654 5.703717411169502e-8 2.026548080180679e-7 7.474568537231698e-8 2237/1763/5982/5422/6117/10714/5558/6118/3978/5557/5985/5984/23649/5424/54107/5425/5111/6119/5427/5983/56655/57804/5426/5981 24 Human_herpesvirus_8_type_P R-HSA-5260271 Diseases of Immune System 24/5323 24/10654 5.703717411169502e-8 2.026548080180679e-7 7.474568537231698e-8 4790/10333/4792/929/51135/7187/3551/8517/5970/7096/4791/81793/7098/695/81622/23643/1147/7099/4615/7100/114609/948/7097/148022 24 Human_herpesvirus_8_type_P R-HSA-5602358 Diseases associated with the TLR signaling cascade 24/5323 24/10654 5.703717411169502e-8 2.026548080180679e-7 7.474568537231698e-8 4790/10333/4792/929/51135/7187/3551/8517/5970/7096/4791/81793/7098/695/81622/23643/1147/7099/4615/7100/114609/948/7097/148022 24 Human_herpesvirus_8_type_P R-HSA-933542 TRAF6 mediated NF-kB activation 24/5323 24/10654 5.703717411169502e-8 2.026548080180679e-7 7.474568537231698e-8 4790/4792/177/64135/3551/6283/4214/28512/8517/5970/23586/84282/4791/351/7706/7189/28511/1147/7186/57506/4793/3146/6288/6285 24 Human_herpesvirus_8_type_P R-HSA-8878171 Transcriptional regulation by RUNX1 160/5323 239/10654 6.001204262644144e-8 2.1268751631083907e-7 7.844607454550083e-8 1912/9070/5689/1437/5579/5682/1459/6045/9021/5929/27327/80012/1460/143471/5705/5709/5695/28996/1457/1911/6603/10413/5711/1387/3558/5683/10138/57332/5699/8312/5702/192669/83737/5371/57492/6688/4343/4778/5696/5691/7314/5718/84661/25/4773/196528/5700/122706/5707/23198/86/100506658/865/7082/23309/51412/6714/2099/9861/8850/84733/5588/6604/8289/5698/5692/5713/6602/595/5710/3458/896/5719/6233/161882/26523/5781/1493/23429/55193/6015/55904/6595/3562/6597/6929/8535/3674/7122/1378/6938/3958/5706/6599/4331/57678/2623/5714/5688/5687/5708/6886/4602/5704/7311/7161/860/58508/25942/648/5694/6601/23466/4297/27161/894/5684/5720/902/2624/11091/640/8085/5690/2625/57690/5717/9491/4005/6598/10197/192670/5196/7316/10213/5079/10398/1513/5715/5701/5685/5686/2033/1021/84333/6605/50943/3065/861/23112/9757/5716/9739/3276/3559/7057/1022/5693/5721/1997 160 Human_herpesvirus_8_type_P R-HSA-1839126 FGFR2 mutant receptor activation 31/5323 33/10654 6.159486638714706e-8 2.1665994251678977e-7 7.99112345496408e-8 2250/5431/5435/5433/5439/2252/8823/8074/5438/2249/2248/2247/2246/2251/2963/5434/5436/2263/2962/5432/22916/5440/5430/8817/5441/2254/4686/26281/5437/2255/27006 31 Human_herpesvirus_8_type_P R-HSA-1980145 Signaling by NOTCH2 31/5323 33/10654 6.159486638714706e-8 2.1665994251678977e-7 7.99112345496408e-8 182/23385/4853/9794/57534/388585/28514/7314/55534/3280/84441/3714/102/5664/3002/6233/5663/142678/10046/9148/83464/7311/55851/51107/2208/7316/54492/2033/1385/54567/3516 31 Human_herpesvirus_8_type_P R-HSA-389356 CD28 co-stimulation 31/5323 33/10654 6.159486638714706e-8 2.1665994251678977e-7 7.99112345496408e-8 5295/941/2534/2885/2475/5062/5879/1326/5290/57761/9020/6714/10000/7525/7409/3932/940/253260/5170/64223/8503/4067/5063/998/208/79109/5058/207/55615/942/5296 31 Human_herpesvirus_8_type_P R-HSA-4570464 SUMOylation of RNA binding proteins 41/5323 47/10654 8.15103123035086e-8 2.8599752970333315e-7 1.0548519219222927e-7 1912/23165/6045/80012/348995/6613/57122/23511/3190/1911/23279/23225/57332/9972/8021/55746/10762/79902/9883/84733/6396/129401/7703/6015/4928/5903/55706/7175/8535/4927/8086/7329/648/9631/79023/23636/3183/53371/9688/7341/8480 41 Human_herpesvirus_8_type_P R-HSA-168276 NS1 Mediated Effects on Host Pathways 36/5323 40/10654 8.645658714347642e-8 3.0259805500216746e-7 1.1160800592231967e-7 3839/23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/402569/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/4927/10898/3840/8086/3837/9631/79023/23636/53371/9688/8480 36 Human_herpesvirus_8_type_P R-HSA-69205 G1/S-Specific Transcription 27/5323 28/10654 1.0273402352032636e-7 3.586768513476407e-7 1.3229169020640172e-7 5422/1869/4998/5928/990/8900/6241/7027/898/5934/1876/983/7298/1719/26271/8318/286826/5111/91750/1874/81620/55957/1875/5933/3065/7083/132660 27 Human_herpesvirus_8_type_P R-HSA-176033 Interactions of Vpr with host cellular proteins 33/5323 36/10654 1.0656816077420228e-7 3.702256844674138e-7 1.3655127553393562e-7 23165/348995/57122/23511/292/23279/23225/3836/9972/8021/55746/10762/79902/11168/9883/6396/129401/4928/5903/55706/7175/293/4927/8086/9631/3159/79023/23636/53371/9688/8815/8480/291 33 Human_herpesvirus_8_type_P R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 33/5323 36/10654 1.0656816077420228e-7 3.702256844674138e-7 1.3655127553393562e-7 71/51517/147179/10094/8976/2885/3071/5879/26999/25/10093/10006/5594/10810/23191/10109/10787/5747/10152/10092/10163/55845/998/695/10097/60/5595/10458/10552/8936/10096/7454/10095 33 Human_herpesvirus_8_type_P R-HSA-112409 RAF-independent MAPK1/3 activation 23/5323 23/10654 1.144079618832887e-7 3.916593731624993e-7 1.4445671714294108e-7 1844/1850/1848/1852/5605/3717/1847/3569/3572/1849/5594/983/80824/1843/3570/7297/5781/8682/1846/11221/3716/5595/5604 23 Human_herpesvirus_8_type_P R-HSA-166208 mTORC1-mediated signalling 23/5323 23/10654 1.144079618832887e-7 3.916593731624993e-7 1.4445671714294108e-7 6198/29904/10325/2475/10670/64121/84335/1981/1977/1978/57521/28956/6194/389541/58528/64223/6009/1975/55004/7529/153129/8649/10542 23 Human_herpesvirus_8_type_P R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 23/5323 23/10654 1.144079618832887e-7 3.916593731624993e-7 1.4445671714294108e-7 5431/5435/5433/5439/51497/5438/7936/6829/25920/2963/5434/5436/2962/5432/22916/5440/5430/5441/7469/4686/9150/5437/6827 23 Human_herpesvirus_8_type_P R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 23/5323 23/10654 1.144079618832887e-7 3.916593731624993e-7 1.4445671714294108e-7 11065/7321/8697/51529/29945/51434/29882/7314/996/983/51433/119504/7324/64682/6233/246184/8881/891/10393/7311/25906/991/7316 23 Human_herpesvirus_8_type_P R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 23/5323 23/10654 1.144079618832887e-7 3.916593731624993e-7 1.4445671714294108e-7 7321/8239/9612/4089/23327/4088/7314/6497/51592/7323/7050/5494/6233/60436/142/4087/7311/64750/54778/7316/9611/3065/6498 23 Human_herpesvirus_8_type_P R-HSA-428930 Thromboxane signalling through TP receptor 23/5323 23/10654 1.144079618832887e-7 3.916593731624993e-7 1.4445671714294108e-7 2788/2769/2782/2776/2787/10681/2792/2785/2783/2784/2791/6915/2786/54331/59345/51764/94235/55970/2767/2793/9630/2790/10672 23 Human_herpesvirus_8_type_P R-HSA-2173789 TGF-beta receptor signaling activates SMADs 30/5323 32/10654 1.1635024977416854e-7 3.9446940104157863e-7 1.4549314683237816e-7 4738/9372/56937/4089/23327/4088/5499/9110/7040/7314/4092/11171/7046/2280/9958/9040/6233/7514/5500/5501/23645/4087/7048/7311/57154/51377/10273/64750/7316/867 30 Human_herpesvirus_8_type_P R-HSA-2871796 FCERI mediated MAPK activation 30/5323 32/10654 1.1635024977416854e-7 3.9446940104157863e-7 1.4549314683237816e-7 3725/4893/5335/2885/3845/3265/5062/5879/5601/5336/5594/4214/7410/7409/2353/6464/2205/3937/10451/2206/6850/4067/5602/6654/5058/6416/5595/5609/5599/2207 30 Human_herpesvirus_8_type_P R-HSA-397795 G-protein beta:gamma signalling 30/5323 32/10654 1.1635024977416854e-7 3.9446940104157863e-7 1.4549314683237816e-7 2788/5331/2782/2787/10681/2792/10000/5294/2785/2783/2784/2791/5170/23236/998/695/2786/208/387/5058/54331/59345/207/9459/51764/94235/5330/55970/2793/2790 30 Human_herpesvirus_8_type_P R-HSA-73863 RNA Polymerase I Transcription Termination 30/5323 32/10654 1.1635024977416854e-7 3.9446940104157863e-7 1.4549314683237816e-7 5435/2965/64425/2967/30834/404672/2068/9533/5434/9015/79101/221830/7270/4331/9013/2966/2071/10849/6908/5440/902/9014/25885/5441/51082/7343/5437/2968/84172/1022 30 Human_herpesvirus_8_type_P R-HSA-351202 Metabolism of polyamines 49/5323 59/10654 1.2236597257780639e-7 4.1386760436772493e-7 1.5264783522484451e-7 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/5718/1728/51582/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6303/5706/5714/5688/5687/5708/5704/262/5694/5684/5720/5690/5717/9491/10197/10213/5715/6611/5701/5685/5686/5716/5693/5721 49 Human_herpesvirus_8_type_P R-HSA-177929 Signaling by EGFR 42/5323 49/10654 1.6673283880504482e-7 5.625733913637843e-7 2.074953667320134e-7 5295/374/4893/5335/55824/6456/6868/30011/2885/8874/3845/3265/10252/5829/7314/1839/5290/2060/2069/102/6714/9146/6455/1445/6233/29924/5781/6464/5782/998/6654/7311/1956/2549/10253/685/58513/7316/1950/867/5774/10254 42 Human_herpesvirus_8_type_P R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 32/5323 35/10654 1.965940039921222e-7 6.617410612844879e-7 2.4407162923222427e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/7884/4927/10482/8086/22916/9631/79023/23636/4686/53371/9688/10189/8480 32 Human_herpesvirus_8_type_P R-HSA-1538133 G0 and Early G1 26/5323 27/10654 1.9900062313696192e-7 6.6349259894243e-7 2.4471765329638873e-7 9134/1869/4609/5928/990/8900/7027/7153/898/5934/993/890/983/1859/286826/5111/91750/1874/55957/1017/4605/4149/1875/5933/3065/132660 26 Human_herpesvirus_8_type_P R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 26/5323 27/10654 1.9900062313696192e-7 6.6349259894243e-7 2.4471765329638873e-7 5431/5435/5433/8732/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/5440/902/5430/5441/5437/2968/1022 26 Human_herpesvirus_8_type_P R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 26/5323 27/10654 1.9900062313696192e-7 6.6349259894243e-7 2.4471765329638873e-7 356/90249/836/929/26060/219699/1612/8737/841/8797/1613/8772/8717/8743/8837/8795/23643/7186/842/355/7099/9500/23604/1630/353376/148022 26 Human_herpesvirus_8_type_P R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 26/5323 27/10654 1.9900062313696192e-7 6.6349259894243e-7 2.4471765329638873e-7 5431/5435/5433/8732/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/5440/902/5430/5441/5437/2968/1022 26 Human_herpesvirus_8_type_P R-HSA-5654733 Negative regulation of FGFR4 signaling 29/5323 31/10654 2.1934627398854295e-7 7.295985992952244e-7 2.6909969659413136e-7 8569/9965/2264/2885/5518/7314/5515/8823/5594/8074/2249/6714/2247/6233/2246/2251/5781/673/7311/5595/5516/10253/8817/2254/7316/152831/26281/10818/867 29 Human_herpesvirus_8_type_P R-HSA-1250196 SHC1 events in ERBB2 signaling 22/5323 22/10654 2.2946339383948754e-7 7.525757462288088e-7 2.7757441580877775e-7 4893/5578/2064/145957/9542/2885/3845/3265/1839/2065/2069/5580/6464/5782/3084/6654/10718/1956/685/1950/2066/5581 22 Human_herpesvirus_8_type_P R-HSA-198753 ERK/MAPK targets 22/5323 22/10654 2.2946339383948754e-7 7.525757462288088e-7 2.7757441580877775e-7 9252/1848/1432/6196/5518/6197/51231/5515/1849/5594/5528/5519/5598/4208/6195/5600/1846/5595/5516/1845/4205/2002 22 Human_herpesvirus_8_type_P R-HSA-392170 ADP signalling through P2Y purinoceptor 12 22/5323 22/10654 2.2946339383948754e-7 7.525757462288088e-7 2.7757441580877775e-7 2788/64805/2770/2782/2773/2787/10681/2792/2785/2783/2784/2771/2791/2786/54331/59345/51764/94235/55970/346562/2793/2790 22 Human_herpesvirus_8_type_P R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 22/5323 22/10654 2.2946339383948754e-7 7.525757462288088e-7 2.7757441580877775e-7 3725/7531/356/7001/4001/84290/826/823/2801/993/351/6648/1020/4000/994/2309/10018/831/824/995/8851/5052 22 Human_herpesvirus_8_type_P R-HSA-8863678 Neurodegenerative Diseases 22/5323 22/10654 2.2946339383948754e-7 7.525757462288088e-7 2.7757441580877775e-7 3725/7531/356/7001/4001/84290/826/823/2801/993/351/6648/1020/4000/994/2309/10018/831/824/995/8851/5052 22 Human_herpesvirus_8_type_P R-HSA-912631 Regulation of signaling by CBL 22/5323 22/10654 2.2946339383948754e-7 7.525757462288088e-7 2.7757441580877775e-7 5295/5291/2534/2885/1399/7314/5290/6233/7525/7409/6850/8503/2889/4067/29760/7311/5293/7316/3055/867/1398/5296 22 Human_herpesvirus_8_type_P R-HSA-111996 Ca-dependent events 34/5323 38/10654 2.831814907949797e-7 9.265961803454335e-7 3.4175881263629135e-7 817/5578/5582/107/814/818/5567/5594/112/5573/111/5613/5580/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5321/5575/114/108/5576/1385/808 34 Human_herpesvirus_8_type_P R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 41/5323 48/10654 2.882025315584044e-7 9.408374986140951e-7 3.4701147407081056e-7 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/8812/905/2071/5432/22916/6917/5440/902/5430/6749/5441/7469/4686/9150/5437/6827/2968/1022/8178 41 Human_herpesvirus_8_type_P R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 43/5323 51/10654 3.1584888059723237e-7 1.0287022569451527e-6 3.794188551034005e-7 51807/10381/1780/5048/8655/84516/832/636/7846/113457/2590/81027/51164/79861/23299/8398/5870/10376/10540/140735/84617/11258/1783/10382/93661/55860/830/7277/10671/1639/347733/51143/10383/84790/5049/7280/829/1778/5321/5050/1781/10121/51560 43 Human_herpesvirus_8_type_P R-HSA-447115 Interleukin-12 family signaling 47/5323 57/10654 3.4263893615385814e-7 1.1133787140149616e-6 4.106502869183228e-7 3593/5908/1265/3313/6175/5898/3717/3181/4001/3594/4282/5062/3572/10148/1072/6627/9049/27250/9987/3185/149233/3458/5478/302/552900/51561/7297/6775/9446/821/4478/6774/6772/998/6648/3716/2939/6888/3586/829/5055/6647/6950/6845/375/5721/5034 47 Human_herpesvirus_8_type_P R-HSA-5693538 Homology Directed Repair 98/5323 138/10654 3.474792279618061e-7 1.126505239037468e-6 4.1549177634045707e-7 2237/83990/151987/5892/9156/1763/7486/5982/472/6613/80198/4683/165918/84126/8900/8924/2067/672/6117/7334/10714/348654/83695/7314/6118/25/5888/51588/51720/63967/5531/116028/890/197342/7517/9656/84464/5985/5984/6233/7158/6047/5884/5810/5424/80010/7516/7515/54107/580/11073/5425/641/5111/6119/3364/10524/5427/144715/5889/5429/142/1111/10721/7329/79728/51426/146956/7311/3980/5983/10038/56655/51750/1017/54962/5893/5883/10111/57804/675/51548/545/7336/2072/29086/7316/5426/10635/7341/8914/23514/5932/9025/79184/7156/5890/5981 98 Human_herpesvirus_8_type_P R-HSA-159227 Transport of the SLBP independent Mature mRNA 31/5323 34/10654 3.617570626909431e-7 1.1647418471536773e-6 4.295946812155485e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10482/8086/22916/9631/79023/23636/4686/53371/9688/10189/8480 31 Human_herpesvirus_8_type_P R-HSA-4085377 SUMOylation of SUMOylation proteins 31/5323 34/10654 3.617570626909431e-7 1.1647418471536773e-6 4.295946812155485e-7 23165/348995/6613/57122/23511/23279/23225/9972/8021/55746/51588/10762/79902/9883/6396/129401/4928/5903/55706/7175/10210/4927/8086/7329/9631/79023/23636/53371/9688/7341/8480 31 Human_herpesvirus_8_type_P R-HSA-5693537 Resolution of D-Loop Structures 31/5323 34/10654 3.617570626909431e-7 1.1647418471536773e-6 4.295946812155485e-7 83990/5892/9156/1763/7486/472/80198/4683/672/348654/5888/116028/197342/7517/84464/80010/7516/580/641/10524/5889/79728/146956/51750/10111/675/10635/23514/5932/7156/5890 31 Human_herpesvirus_8_type_P R-HSA-2173788 Downregulation of TGF-beta receptor signaling 25/5323 26/10654 3.849453822163923e-7 1.2309503472237818e-6 4.5401452974325695e-7 9372/56937/23327/4088/5499/9110/7040/7314/4092/11171/7046/9958/6233/7514/5500/5501/23645/4087/7048/7311/57154/51377/10273/64750/7316 25 Human_herpesvirus_8_type_P R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 25/5323 26/10654 3.849453822163923e-7 1.2309503472237818e-6 4.5401452974325695e-7 83990/5892/9156/1763/7486/472/4683/672/5888/116028/7517/80010/7516/580/641/10524/5889/79728/51750/10111/675/10635/5932/7156/5890 25 Human_herpesvirus_8_type_P R-HSA-6803529 FGFR2 alternative splicing 25/5323 26/10654 3.849453822163923e-7 1.2309503472237818e-6 4.5401452974325695e-7 54845/5431/5435/5433/5439/7072/7073/5438/3185/4670/5725/2963/5434/5436/2962/5432/22916/5440/23543/5430/3178/5441/4686/5437/3187 25 Human_herpesvirus_8_type_P R-HSA-5619084 ABC transporter disorders 60/5323 77/10654 3.951674039490723e-7 1.2607721935518023e-6 4.650137967463723e-7 5244/5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/3767/5702/51009/5696/5691/7314/5718/5700/122706/5707/10956/79139/23198/9861/5698/5692/5713/5710/5719/6233/10058/5706/19/335/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 60 Human_herpesvirus_8_type_P R-HSA-5654696 Downstream signaling of activated FGFR2 28/5323 30/10654 4.1264900140423574e-7 1.3135682013026237e-6 4.844866818106412e-7 5295/4893/2250/5335/2885/2252/3845/3265/5290/8823/8074/2249/2248/2247/2246/2251/5781/6464/2263/6654/2549/8817/10817/2254/26281/10818/2255/27006 28 Human_herpesvirus_8_type_P R-HSA-109704 PI3K Cascade 38/5323 44/10654 4.3892546829171926e-7 1.3940589929716682e-6 5.141743040699005e-7 5295/2250/5291/9965/2264/2885/8660/9846/2252/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/2246/2251/5781/30849/5170/2322/2263/208/2549/8817/2254/152831/5289/26281/10818/2261/2255/27006/5296 38 Human_herpesvirus_8_type_P R-HSA-111931 PKA-mediated phosphorylation of CREB 21/5323 21/10654 4.6018186848269944e-7 1.4484919215999062e-6 5.342509388012972e-7 107/5567/112/5573/111/5613/196883/115/801/805/5568/113/5566/5577/109/5575/114/108/5576/1385/808 21 Human_herpesvirus_8_type_P R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 21/5323 21/10654 4.6018186848269944e-7 1.4484919215999062e-6 5.342509388012972e-7 4790/4792/1660/3551/11035/8737/29110/28512/8517/5970/3661/4791/23220/7098/81030/28511/1147/147945/4615/4793/148022 21 Human_herpesvirus_8_type_P R-HSA-389513 CTLA4 inhibitory signaling 21/5323 21/10654 4.6018186848269944e-7 1.4484919215999062e-6 5.342509388012972e-7 5526/941/2534/5518/5515/5528/6714/5519/10000/7525/3932/5781/1493/4067/5529/208/5516/5525/207/942/5527 21 Human_herpesvirus_8_type_P R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 21/5323 21/10654 4.6018186848269944e-7 1.4484919215999062e-6 5.342509388012972e-7 2237/5982/6117/10714/6118/328/3978/5985/5984/5424/54107/5423/5425/5111/6119/5427/5983/56655/57804/5426/5981 21 Human_herpesvirus_8_type_P R-HSA-6783783 Interleukin-10 signaling 40/5323 47/10654 4.964988358008924e-7 1.555843790583197e-6 5.738458001402883e-7 729230/7124/1437/3593/5743/941/3383/3576/2920/1435/7133/3606/6347/3588/3569/3976/3627/7076/7297/3557/6351/6774/1440/3552/3716/1234/3586/3554/2208/3553/1230/2919/2357/6352/6348/6364/7132/942/6363/5724 40 Human_herpesvirus_8_type_P R-HSA-9020591 Interleukin-12 signaling 40/5323 47/10654 4.964988358008924e-7 1.555843790583197e-6 5.738458001402883e-7 3593/5908/1265/3313/6175/5898/3717/3181/4001/3594/4282/5062/1072/6627/9049/27250/9987/3185/3458/5478/302/552900/7297/6775/9446/4478/998/6648/3716/2939/6888/3586/829/5055/6647/6950/6845/375/5721/5034 40 Human_herpesvirus_8_type_P R-HSA-5689880 Ub-specific processing proteases 146/5323 220/10654 5.064505996737209e-7 1.5835022083131673e-6 5.840471243020923e-7 5689/5682/79594/7419/10474/84196/7375/9817/91833/3091/143471/5705/11274/55031/8239/5709/5695/4792/4609/4194/4089/5711/4088/5683/408/64135/5699/8312/5702/8900/8975/57599/377630/6881/51616/1540/80351/5696/5691/7314/5718/90865/2648/5700/122706/5707/8737/55611/57646/23198/63967/8517/993/890/7417/4092/1643/9861/23586/81847/64426/7046/6502/5698/9146/5692/5713/5710/10454/7157/10869/9958/8313/5719/6233/9804/23770/8607/7874/10600/23326/93624/8237/4303/409/330/5706/27005/7416/5423/25862/9738/8658/84132/5714/79589/55288/27430/5688/9097/5687/8078/5708/4087/63891/7189/5704/7311/367/5694/9960/23358/23032/5684/8295/5720/7186/6885/991/5690/2625/5717/9491/4086/1080/57695/10197/64750/7316/10213/8678/9100/5715/5701/329/9099/5685/5686/5728/5716/9736/5693/154/10254/5721/4193 146 Human_herpesvirus_8_type_P R-HSA-191859 snRNP Assembly 44/5323 53/10654 5.614472317861724e-7 1.7476908299184614e-6 6.44605228855573e-7 23165/6633/6606/8487/348995/57122/23511/23279/23225/79084/9972/8021/55746/96764/10762/79902/9883/6636/10419/6396/129401/50628/4928/6635/5903/6632/55706/7175/6637/4927/51808/8086/22916/11218/9631/79023/23636/4686/53371/9688/1207/6634/8480/6628 44 Human_herpesvirus_8_type_P R-HSA-194441 Metabolism of non-coding RNA 44/5323 53/10654 5.614472317861724e-7 1.7476908299184614e-6 6.44605228855573e-7 23165/6633/6606/8487/348995/57122/23511/23279/23225/79084/9972/8021/55746/96764/10762/79902/9883/6636/10419/6396/129401/50628/4928/6635/5903/6632/55706/7175/6637/4927/51808/8086/22916/11218/9631/79023/23636/4686/53371/9688/1207/6634/8480/6628 44 Human_herpesvirus_8_type_P R-HSA-9006931 Signaling by Nuclear Receptors 191/5323 299/10654 6.10834902721149e-7 1.8972289362663503e-6 6.997597468142826e-7 5295/2788/374/3725/4893/857/7764/79718/7031/5160/2770/10901/27327/10274/5915/8644/1381/5431/5435/5433/1509/5469/1105/9612/4609/124/1387/6907/8312/2782/5439/192669/10499/1386/5914/4343/3845/904/1071/7392/3265/27329/8877/2773/10062/2787/6387/1839/5290/4316/5594/2069/10681/51523/5481/5438/348/4313/865/1655/6667/2792/6714/2099/2494/8850/5467/10000/2785/595/2783/2784/2771/7514/1025/2353/6257/26523/801/2791/2957/805/5105/5170/2963/3838/5434/5590/6464/112724/1374/7090/5241/5747/5436/1903/3315/4318/126/5885/19/57678/7033/2962/8503/10524/5346/2171/8243/4602/9682/2786/208/3326/23030/6908/1956/5536/3169/858/5432/3480/10728/5595/7528/3727/27161/2354/596/5440/8841/685/54331/4435/347/2309/9687/59345/8204/5430/207/5451/2625/57690/6722/1027/51764/94235/5441/10735/6720/192670/2100/1950/9611/55970/2874/2194/4314/127/346562/2289/7391/2958/5437/2793/3320/1382/2033/4846/9126/3065/2002/2066/861/23028/6256/23112/7376/10498/1385/1738/5296/808/6258/3276/5916/8202/8648/2288/2790 191 Human_herpesvirus_8_type_P R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 30/5323 33/10654 6.63904083644391e-7 2.0440110408920312e-6 7.538977616876307e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/3303/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/3304/9631/79023/23636/53371/9688/8480 30 Human_herpesvirus_8_type_P R-HSA-180746 Nuclear import of Rev protein 30/5323 33/10654 6.63904083644391e-7 2.0440110408920312e-6 7.538977616876307e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/1104/3837/9631/79023/23636/53371/9688/8480 30 Human_herpesvirus_8_type_P R-HSA-180910 Vpr-mediated nuclear import of PICs 30/5323 33/10654 6.63904083644391e-7 2.0440110408920312e-6 7.538977616876307e-7 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/11168/9883/6396/129401/4928/5903/55706/7175/4927/8086/9631/3159/79023/23636/53371/9688/8815/8480 30 Human_herpesvirus_8_type_P R-HSA-5693568 Resolution of D-loop Structures through Holliday Junction Intermediates 30/5323 33/10654 6.63904083644391e-7 2.0440110408920312e-6 7.538977616876307e-7 83990/5892/9156/1763/7486/472/80198/4683/672/348654/5888/116028/197342/7517/84464/80010/7516/580/641/10524/5889/79728/146956/10111/675/10635/23514/5932/7156/5890 30 Human_herpesvirus_8_type_P R-HSA-8856828 Clathrin-mediated endocytosis 102/5323 146/10654 7.202506950494797e-7 2.2126478775865023e-6 8.160965126623617e-7 374/71/8674/4738/1212/1785/950/10094/54874/55738/10980/7037/2017/408/9322/10987/6456/185/8976/30011/2885/163/11037/1759/3312/9185/7314/23396/1839/161/7018/5868/10618/10093/1856/8322/2060/2069/1601/6453/1129/9146/6455/4074/10920/26119/29979/6233/7474/6844/1213/2580/1211/29924/1175/10109/6869/1173/6857/23048/409/382/160/338/8218/920/26052/8867/10092/9829/2873/10097/7311/1956/60/8533/8673/51138/9318/685/1080/29978/58513/7316/1950/273/64708/10552/26130/3949/867/9341/915/917/5878/10096/3575/6845/551/154/10254/50813 102 Human_herpesvirus_8_type_P R-HSA-9006115 Signaling by NTRK2 (TRKB) 24/5323 25/10654 7.435436844171265e-7 2.2693404858457635e-6 8.370065907469881e-7 5295/627/4893/5335/2534/2885/3845/3265/5879/5290/6714/4909/5781/4908/6464/2904/7074/6654/2549/1020/4915/10817/10818/8851 24 Human_herpesvirus_8_type_P R-HSA-9006335 Signaling by Erythropoietin 24/5323 25/10654 7.435436844171265e-7 2.2693404858457635e-6 8.370065907469881e-7 5295/4893/5335/5291/6776/3717/2885/2056/8660/3845/3265/1399/5290/5336/5294/2057/7409/6777/6464/2889/4067/6654/5293/2549 24 Human_herpesvirus_8_type_P R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 24/5323 25/10654 7.435436844171265e-7 2.2693404858457635e-6 8.370065907469881e-7 22938/1387/9794/9787/388585/23286/2648/55534/3280/84441/4854/8850/5087/2173/23129/171558/10046/6772/26508/23493/4851/23462/2033/3516 24 Human_herpesvirus_8_type_P R-HSA-186763 Downstream signal transduction 27/5323 29/10654 7.745708854034916e-7 2.353825563202403e-6 8.681674354982867e-7 5295/4893/5335/5291/6776/2885/8440/9564/3845/3265/1399/5290/5921/6778/6714/6777/5781/6774/6772/2889/5159/2886/6654/1398/5155/5296/5156 27 Human_herpesvirus_8_type_P R-HSA-5654732 Negative regulation of FGFR3 signaling 27/5323 29/10654 7.745708854034916e-7 2.353825563202403e-6 8.681674354982867e-7 2250/8569/2885/5518/7314/5515/8823/5594/8074/2249/6714/2247/6233/2246/5781/673/7311/5595/5516/10253/8817/2254/7316/26281/10818/2261/867 27 Human_herpesvirus_8_type_P R-HSA-167169 HIV Transcription Elongation 39/5323 46/10654 8.523541515835896e-7 2.5735242302105377e-6 9.491994504872594e-7 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/7469/4686/9150/5437/6827/2968/1022/8178 39 Human_herpesvirus_8_type_P R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 39/5323 46/10654 8.523541515835896e-7 2.5735242302105377e-6 9.491994504872594e-7 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/7469/4686/9150/5437/6827/2968/1022/8178 39 Human_herpesvirus_8_type_P R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 39/5323 46/10654 8.523541515835896e-7 2.5735242302105377e-6 9.491994504872594e-7 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/7469/4686/9150/5437/6827/2968/1022/8178 39 Human_herpesvirus_8_type_P R-HSA-111933 Calmodulin induced events 32/5323 36/10654 9.168007497354782e-7 2.716256213680714e-6 1.0018436489317263e-6 817/5578/5582/107/814/818/5567/112/5573/111/5613/5580/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5575/114/108/5576/1385/808 32 Human_herpesvirus_8_type_P R-HSA-111997 CaM pathway 32/5323 36/10654 9.168007497354782e-7 2.716256213680714e-6 1.0018436489317263e-6 817/5578/5582/107/814/818/5567/112/5573/111/5613/5580/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5575/114/108/5576/1385/808 32 Human_herpesvirus_8_type_P R-HSA-177243 Interactions of Rev with host cellular proteins 32/5323 36/10654 9.168007497354782e-7 2.716256213680714e-6 1.0018436489317263e-6 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/1104/5905/3837/9631/79023/23636/53371/9688/8480 32 Human_herpesvirus_8_type_P R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 20/5323 20/10654 9.227935111154095e-7 2.716256213680714e-6 1.0018436489317263e-6 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Human_herpesvirus_8_type_P R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 20/5323 20/10654 9.227935111154095e-7 2.716256213680714e-6 1.0018436489317263e-6 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Human_herpesvirus_8_type_P R-HSA-3232118 SUMOylation of transcription factors 20/5323 20/10654 9.227935111154095e-7 2.716256213680714e-6 1.0018436489317263e-6 9112/6613/7022/6612/4286/6670/51588/7157/668/7158/9063/8554/7020/1029/7329/7021/3090/7341/10401/4193 20 Human_herpesvirus_8_type_P R-HSA-418217 G beta:gamma signalling through PLC beta 20/5323 20/10654 9.227935111154095e-7 2.716256213680714e-6 1.0018436489317263e-6 2788/5331/2782/2787/10681/2792/2785/2783/2784/2791/23236/2786/54331/59345/51764/94235/5330/55970/2793/2790 20 Human_herpesvirus_8_type_P R-HSA-5213460 RIPK1-mediated regulated necrosis 20/5323 20/10654 9.227935111154095e-7 2.716256213680714e-6 1.0018436489317263e-6 356/7314/11035/8737/841/8797/6233/8772/331/8717/8743/330/8837/197259/7311/8795/7186/355/7316/329 20 Human_herpesvirus_8_type_P R-HSA-5218859 Regulated Necrosis 20/5323 20/10654 9.227935111154095e-7 2.716256213680714e-6 1.0018436489317263e-6 356/7314/11035/8737/841/8797/6233/8772/331/8717/8743/330/8837/197259/7311/8795/7186/355/7316/329 20 Human_herpesvirus_8_type_P R-HSA-69186 Lagging Strand Synthesis 20/5323 20/10654 9.227935111154095e-7 2.716256213680714e-6 1.0018436489317263e-6 2237/1763/5982/5422/6117/10714/5558/6118/3978/5557/5985/5984/23649/5424/5425/5111/6119/5983/57804/5981 20 Human_herpesvirus_8_type_P R-HSA-8964616 G beta:gamma signalling through CDC42 20/5323 20/10654 9.227935111154095e-7 2.716256213680714e-6 1.0018436489317263e-6 2788/2782/2787/10681/2792/2785/2783/2784/2791/998/2786/5058/54331/59345/9459/51764/94235/55970/2793/2790 20 Human_herpesvirus_8_type_P R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 20/5323 20/10654 9.227935111154095e-7 2.716256213680714e-6 1.0018436489317263e-6 22938/1387/4088/4853/9794/388585/2648/55534/3280/84441/8850/2324/10046/59/4855/23493/4851/23462/2033/3516 20 Human_herpesvirus_8_type_P R-HSA-5628897 TP53 Regulates Metabolic Genes 65/5323 86/10654 9.498607864522269e-7 2.7900921222093596e-6 1.0290767338115546e-6 5563/7531/10971/9997/27327/7295/7533/2810/53632/7001/4514/10325/192669/2475/10670/4513/4343/64121/7296/2936/51422/7249/27244/7534/2821/10000/2877/54541/7157/50484/26523/2744/57521/28956/83667/389541/7532/58528/51241/64223/5571/10128/6009/8626/208/55004/5562/5564/5565/7248/7529/27161/27165/207/57690/192670/153129/2539/54205/143686/8649/5728/23112/10542/5052 65 Human_herpesvirus_8_type_P R-HSA-5656169 Termination of translesion DNA synthesis 29/5323 32/10654 1.2149745080608137e-6 3.56139402675326e-6 1.3135579659517132e-6 5982/6117/10714/7314/6118/9636/11201/51455/5985/5984/6233/5424/54107/7706/5425/5111/6119/5427/5429/9246/51426/7311/5983/56655/57804/7316/5426/9100/5981 29 Human_herpesvirus_8_type_P R-HSA-5627123 RHO GTPases activate PAKs 23/5323 24/10654 1.433936080629941e-6 4.185784368145906e-6 1.543853434703125e-6 2017/79784/4628/5062/5879/4638/4659/4771/801/5500/805/2316/10627/5063/998/5058/4629/3984/4627/10398/4637/103910/808 23 Human_herpesvirus_8_type_P R-HSA-982772 Growth hormone receptor signaling 23/5323 24/10654 1.433936080629941e-6 4.185784368145906e-6 1.543853434703125e-6 5777/5770/9021/6776/3717/5618/6868/8660/1154/3667/2690/5594/5617/8835/6777/6774/6772/8651/1442/4067/2689/5595/2688 23 Human_herpesvirus_8_type_P R-HSA-114604 GPVI-mediated activation cascade 31/5323 35/10654 1.6417707676067727e-6 4.772668326493242e-6 1.7603153293391456e-6 5295/5777/5291/388/2534/51206/51266/5879/5290/10630/5336/5880/5294/7410/7409/3932/5781/5170/5590/3937/10451/1277/6850/8503/4067/998/387/391/5296/1278/2207 31 Human_herpesvirus_8_type_P R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 31/5323 35/10654 1.6417707676067727e-6 4.772668326493242e-6 1.7603153293391456e-6 23165/91754/348995/57122/23511/23279/23225/9972/8021/55746/10762/983/79902/9883/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/9631/140609/79023/23636/53371/9688/8480 31 Human_herpesvirus_8_type_P R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 19/5323 19/10654 1.850284500511386e-6 5.2913623825600006e-6 1.951626569859036e-6 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Human_herpesvirus_8_type_P R-HSA-163615 PKA activation 19/5323 19/10654 1.850284500511386e-6 5.2913623825600006e-6 1.951626569859036e-6 107/5567/112/5573/111/196883/115/801/805/5568/113/5566/5577/109/5575/114/108/5576/808 19 Human_herpesvirus_8_type_P R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 19/5323 19/10654 1.850284500511386e-6 5.2913623825600006e-6 1.951626569859036e-6 11065/7321/8697/51529/29945/51434/29882/996/51433/119504/7324/64682/246184/8881/10393/51343/25906/991/8556 19 Human_herpesvirus_8_type_P R-HSA-176412 Phosphorylation of the APC/C 19/5323 19/10654 1.850284500511386e-6 5.2913623825600006e-6 1.951626569859036e-6 11065/7321/8697/51529/29945/51434/29882/996/983/51433/119504/7324/64682/246184/8881/891/10393/25906/5347 19 Human_herpesvirus_8_type_P R-HSA-3928664 Ephrin signaling 19/5323 19/10654 1.850284500511386e-6 5.2913623825600006e-6 1.951626569859036e-6 1947/2051/2050/2047/2534/1948/8440/8874/5062/5879/6714/1949/10627/2049/5063/6386/2048/5058/28964 19 Human_herpesvirus_8_type_P R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 19/5323 19/10654 1.850284500511386e-6 5.2913623825600006e-6 1.951626569859036e-6 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Human_herpesvirus_8_type_P R-HSA-77595 Processing of Intronless Pre-mRNAs 19/5323 19/10654 1.850284500511386e-6 5.2913623825600006e-6 1.951626569859036e-6 51585/81608/1477/53981/11051/8106/1478/23283/10914/10898/51692/22916/1479/79869/29894/4686/8189/10978/55339 19 Human_herpesvirus_8_type_P R-HSA-8851708 Signaling by FGFR2 IIIa TM 19/5323 19/10654 1.850284500511386e-6 5.2913623825600006e-6 1.951626569859036e-6 5431/5435/5433/5439/5438/2247/2246/2963/5434/5436/2263/2962/5432/22916/5440/5430/5441/4686/5437 19 Human_herpesvirus_8_type_P R-HSA-5689896 Ovarian tumor domain proteases 33/5323 38/10654 2.0093651604366057e-6 5.723029920514786e-6 2.110839599606322e-6 7321/324/64135/7187/7314/8737/8767/55611/8517/80124/983/2099/23586/7128/7157/6233/55593/84282/10318/7706/79155/79589/64127/7189/7311/387/56957/10392/57506/7316/7415/5728/78990 33 Human_herpesvirus_8_type_P R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 33/5323 38/10654 2.0093651604366057e-6 5.723029920514786e-6 2.110839599606322e-6 5908/1265/3313/6175/5898/3181/4001/4282/5062/1072/6627/9049/27250/9987/3185/3458/5478/302/552900/6775/9446/4478/998/6648/2939/6888/3586/829/5055/6647/6950/375/5721 33 Human_herpesvirus_8_type_P R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 28/5323 31/10654 2.2168077906173835e-6 6.275751632592874e-6 2.3147013465516684e-6 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/3837/9631/79023/23636/53371/9688/8480 28 Human_herpesvirus_8_type_P R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 28/5323 31/10654 2.2168077906173835e-6 6.275751632592874e-6 2.3147013465516684e-6 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/9631/79023/23636/53371/9688/8480 28 Human_herpesvirus_8_type_P R-HSA-1839124 FGFR1 mutant receptor activation 28/5323 31/10654 2.2168077906173835e-6 6.275751632592874e-6 2.3147013465516684e-6 5295/11052/2250/9530/613/6776/11064/2885/9846/7750/8805/26127/5290/8074/2260/2249/399687/2247/2246/2251/6777/1523/9208/6774/6772/11160/2254/26281 28 Human_herpesvirus_8_type_P R-HSA-8853659 RET signaling 35/5323 41/10654 2.2928650285670397e-6 6.478034327698444e-6 2.3893097845773636e-6 5295/2674/1796/5335/5291/5578/2668/2885/8660/9846/5623/5290/5567/4902/6714/5598/64096/9260/5781/6464/5568/2675/2676/5566/8503/2886/6654/5293/2549/85358/10818/53358/5979/9048/5296 35 Human_herpesvirus_8_type_P R-HSA-5654736 Signaling by FGFR1 41/5323 50/10654 2.6119573975042236e-6 7.364777671920727e-6 2.716369574875187e-6 5295/4893/2250/5335/8569/2885/5518/3845/3265/7314/5515/5290/5594/8074/2260/2249/6714/2248/2247/6233/2246/2251/200734/5781/6464/673/6654/7311/2549/5595/5516/10253/8817/10817/2254/7316/26281/10818/867/2255/27006 41 Human_herpesvirus_8_type_P R-HSA-5654716 Downstream signaling of activated FGFR4 25/5323 27/10654 2.7092548707092343e-6 7.623843206175786e-6 2.811921371072953e-6 5295/4893/5335/9965/2264/2885/3845/3265/5290/8823/8074/2249/2247/2246/2251/5781/6464/6654/2549/8817/10817/2254/152831/26281/10818 25 Human_herpesvirus_8_type_P R-HSA-166663 Initial triggering of complement 22/5323 23/10654 2.7606828968758743e-6 7.72222830199673e-6 2.848208994788754e-6 5199/10584/717/2219/720/714/5648/629/3004/1401/712/716/78989/721/10747/715/2220/1675/713/8547/4153/718 22 Human_herpesvirus_8_type_P R-HSA-389948 PD-1 signaling 22/5323 23/10654 2.7606828968758743e-6 7.72222830199673e-6 2.848208994788754e-6 5777/3115/3113/3117/3127/5133/3126/29126/1445/916/3932/5781/3120/3123/80380/3122/920/3125/3119/919/915/917 22 Human_herpesvirus_8_type_P R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 22/5323 23/10654 2.7606828968758743e-6 7.72222830199673e-6 2.848208994788754e-6 3654/7334/7314/257397/5601/8767/23118/8517/10454/6233/64127/5602/3656/7189/7311/6416/6885/10392/7316/7335/5609/5599 22 Human_herpesvirus_8_type_P R-HSA-381119 Unfolded Protein Response (UPR) 69/5323 94/10654 2.7950276122477035e-6 7.802785417524839e-6 2.877921079444691e-6 10525/1965/1663/5526/811/3576/9570/55738/10130/3309/4801/55062/6347/11340/9820/10488/8720/9695/84699/7094/9114/58477/468/3484/22872/3068/1054/8894/55033/7466/9451/2931/64061/8570/23016/148327/118460/1968/1200/6464/5073/7184/7494/1051/84447/5611/4800/1639/11015/10954/22926/90993/64764/167227/22894/4000/10113/440/9709/4802/1649/2081/30827/51013/467/51360/10106/54512/7709 69 Human_herpesvirus_8_type_P R-HSA-422356 Regulation of insulin secretion 59/5323 78/10654 2.8842705700130674e-6 8.035977607937397e-6 2.96392994479717e-6 2788/6804/5331/2770/5578/2769/3767/2782/3630/2776/8826/2181/6513/2787/5567/1131/10681/112/5573/111/2792/2785/2783/2784/2771/6844/2182/2791/5568/150/6616/5566/2864/23236/2641/6514/2786/5577/6812/54331/5575/59345/51764/94235/114/4082/5330/3790/55970/2778/2767/10768/152/2793/5576/948/5906/9630/2790 59 Human_herpesvirus_8_type_P R-HSA-165054 Rev-mediated nuclear export of HIV RNA 30/5323 34/10654 2.9300067407952583e-6 8.14727170810065e-6 3.0049788292324993e-6 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/1104/5905/9631/79023/23636/53371/9688/8480 30 Human_herpesvirus_8_type_P R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 92/5323 132/10654 2.9422372810040298e-6 8.165143696987515e-6 3.011570600093402e-6 83990/151987/5892/9156/1763/7486/5982/472/6613/80198/4683/165918/84126/8900/8924/2067/672/6117/7334/10714/348654/83695/7314/6118/25/5888/51588/51720/63967/5531/116028/890/197342/7517/9656/84464/5985/5984/6233/7158/6047/5884/5810/5424/80010/7516/54107/580/11073/5425/641/5111/6119/3364/10524/5427/144715/5889/5429/1111/7329/79728/51426/146956/7311/5983/56655/51750/1017/54962/5893/5883/10111/57804/675/51548/545/7336/2072/29086/7316/5426/10635/7341/8914/23514/5932/9025/79184/7156/5890/5981 92 Human_herpesvirus_8_type_P R-HSA-5675482 Regulation of necroptotic cell death 18/5323 18/10654 3.7096373133721284e-6 1.0234234705714872e-5 3.7747186697470787e-6 356/7314/8737/841/8797/6233/8772/331/8717/8743/330/8837/7311/8795/7186/355/7316/329 18 Human_herpesvirus_8_type_P R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 18/5323 18/10654 3.7096373133721284e-6 1.0234234705714872e-5 3.7747186697470787e-6 4893/5578/2885/6196/6197/3845/3265/1839/5594/5598/6195/2520/887/6654/1956/5595/4314/1385 18 Human_herpesvirus_8_type_P R-HSA-8964315 G beta:gamma signalling through BTK 18/5323 18/10654 3.7096373133721284e-6 1.0234234705714872e-5 3.7747186697470787e-6 2788/2782/2787/10681/2792/2785/2783/2784/2791/695/2786/54331/59345/51764/94235/55970/2793/2790 18 Human_herpesvirus_8_type_P R-HSA-73887 Death Receptor Signalling 97/5323 141/10654 3.9738590813473965e-6 1.094172158014831e-5 4.03566284293803e-6 7124/4790/7531/29/356/7375/9530/8878/1894/23385/4792/836/23365/10616/26230/57449/3654/6868/8997/8874/1540/3551/7314/5879/257397/9181/81858/8737/8767/55072/23118/841/8517/8887/6453/9828/5970/5664/8797/7128/396/10454/3066/6233/7410/7409/26574/8772/331/8717/25791/8743/5663/572/7204/7074/330/10451/27005/843/8837/11108/7189/6654/83464/7311/387/6655/55851/51107/8795/1147/4804/8841/7186/56957/6885/5584/10018/8793/835/9459/355/23421/4615/9500/7316/4168/9826/7132/329/9099/4803/3065/5599/7185/10672 97 Human_herpesvirus_8_type_P R-HSA-4090294 SUMOylation of intracellular receptors 27/5323 30/10654 4.031867841396782e-6 1.1058163845702283e-5 4.078610538234562e-6 7068/6613/7181/9759/8856/7067/6612/5914/7421/10062/51588/2516/5465/2099/2494/9063/8554/5241/2908/7329/367/5468/4306/7341/10401/6256/7376 27 Human_herpesvirus_8_type_P R-HSA-6804758 Regulation of TP53 Activity through Acetylation 27/5323 30/10654 4.031867841396782e-6 1.1058163845702283e-5 4.078610538234562e-6 64769/84289/29117/5928/1107/5371/23774/3622/27154/57459/10000/7994/3066/7157/5608/7862/9219/5931/1108/54815/208/53615/5305/207/2033/3065/5300 27 Human_herpesvirus_8_type_P R-HSA-1433557 Signaling by SCF-KIT 36/5323 43/10654 4.216238033914384e-6 1.1541336408010774e-5 4.256820296374752e-6 5295/5777/4893/5578/6776/3717/2534/2885/9846/3845/3265/5879/5290/3815/9306/6714/7525/7409/3932/6777/5781/2241/4318/6774/6772/8651/8503/4067/1111/2886/6654/867/4254/5296/10076/2242 36 Human_herpesvirus_8_type_P R-HSA-6811440 Retrograde transport at the Trans-Golgi-Network 40/5323 49/10654 4.325738801875404e-6 1.1818086396579987e-5 4.358894694582677e-6 400/8674/9382/10228/6293/8675/2800/339122/7110/10618/55275/10466/9827/22836/5870/79571/91949/4074/2803/8677/10139/51542/22796/8775/9648/90196/57589/25839/84316/83548/63908/738/10226/9341/57511/51560/8774/143187/4905/84342 40 Human_herpesvirus_8_type_P R-HSA-110373 Resolution of AP sites via the multiple-nucleotide patch replacement pathway 24/5323 26/10654 5.046723310825938e-6 1.3707991695621805e-5 5.0559532457573416e-6 2237/5982/8505/6117/10714/6118/328/3978/5985/5984/5424/54107/5423/5425/5111/6119/5427/142/5983/10038/56655/57804/5426/5981 24 Human_herpesvirus_8_type_P R-HSA-180024 DARPP-32 events 24/5323 26/10654 5.046723310825938e-6 1.3707991695621805e-5 5.0559532457573416e-6 5530/5499/5518/5515/84152/5567/5573/5528/5519/801/805/5568/5566/5577/1020/5141/5516/5533/5575/5532/5576/5534/5144/808 24 Human_herpesvirus_8_type_P R-HSA-912694 Regulation of IFNA signaling 24/5323 26/10654 5.046723310825938e-6 1.3707991695621805e-5 5.0559532457573416e-6 3443/5777/5770/9021/11274/3445/3444/3451/3448/3439/3452/6773/7297/5781/3446/3455/6772/8651/3440/3454/3716/3456/3441/3449 24 Human_herpesvirus_8_type_P R-HSA-5654726 Negative regulation of FGFR1 signaling 29/5323 33/10654 5.210235085079869e-6 1.4124856964754097e-5 5.2097067172586466e-6 2250/8569/2885/5518/7314/5515/5594/8074/2260/2249/6714/2248/2247/6233/2246/2251/5781/673/7311/5595/5516/10253/2254/7316/26281/10818/867/2255/27006 29 Human_herpesvirus_8_type_P R-HSA-113510 E2F mediated regulation of DNA replication 21/5323 22/10654 5.305269835990154e-6 1.4299836511950472e-5 5.274244866189043e-6 5925/5422/1869/84515/4998/28227/5518/5001/5558/5515/23594/7027/5557/983/5519/23649/4999/5000/891/23595/5516 21 Human_herpesvirus_8_type_P R-HSA-202427 Phosphorylation of CD3 and TCR zeta chains 21/5323 22/10654 5.305269835990154e-6 1.4299836511950472e-5 5.274244866189043e-6 5788/3115/3113/3117/55824/26191/3127/3126/1445/916/3932/3120/3123/3122/920/5795/3125/3119/919/915/917 21 Human_herpesvirus_8_type_P R-HSA-389357 CD28 dependent PI3K/Akt signaling 21/5323 22/10654 5.305269835990154e-6 1.4299836511950472e-5 5.274244866189043e-6 5295/941/2534/2475/1326/5290/57761/9020/10000/3932/940/253260/5170/64223/8503/208/79109/207/55615/942/5296 21 Human_herpesvirus_8_type_P R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 33/5323 39/10654 6.772467857762595e-6 1.81848516715114e-5 6.7071648330192045e-6 5982/25898/6117/10714/55666/7314/6118/9636/11201/51455/5985/5984/6233/5424/54107/7706/5425/5111/6119/83932/5427/5429/9246/51426/7311/5983/56655/57804/7316/5426/9100/7415/5981 33 Human_herpesvirus_8_type_P R-HSA-73933 Resolution of Abasic Sites (AP sites) 33/5323 39/10654 6.772467857762595e-6 1.81848516715114e-5 6.7071648330192045e-6 2237/4913/5982/8505/6117/10714/6118/328/3978/5985/5984/4595/5424/7515/54107/5423/5425/5111/6119/5427/142/4968/3980/5983/10038/56655/11284/57804/6996/5426/8930/5981/7374 33 Human_herpesvirus_8_type_P R-HSA-1489509 DAG and IP3 signaling 35/5323 42/10654 7.125890775097167e-6 1.9061080457341662e-5 7.0303465121531e-6 5335/817/5578/5582/107/814/818/5567/112/5573/111/5613/5580/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5575/114/108/10768/5576/1385/5581/808 35 Human_herpesvirus_8_type_P R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 35/5323 42/10654 7.125890775097167e-6 1.9061080457341662e-5 7.0303465121531e-6 56998/9070/5929/6657/324/6932/90780/25776/6659/7314/51176/8945/6662/7534/7091/83439/6233/7514/7089/331/4221/7090/6736/6934/7088/208/57680/7311/55553/1487/1499/207/8085/7316/3065 35 Human_herpesvirus_8_type_P R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 26/5323 29/10654 7.30822770198432e-6 1.940127618243762e-5 7.155821761823774e-6 5431/5435/5433/55124/84944/5439/11022/91646/5438/56165/54514/5434/5436/122402/143689/5432/4603/5440/8468/5430/5441/5437/3320/54456/9271/136991 26 Human_herpesvirus_8_type_P R-HSA-8863795 Downregulation of ERBB2 signaling 26/5323 29/10654 7.30822770198432e-6 1.940127618243762e-5 7.155821761823774e-6 26469/2064/145957/4145/9542/7314/1839/2065/2069/10000/6233/5782/3084/208/10718/7311/1956/11140/8065/685/10273/207/7316/1950/3320/2066 26 Human_herpesvirus_8_type_P R-HSA-933541 TRAF6 mediated IRF7 activation 26/5323 29/10654 7.30822770198432e-6 1.940127618243762e-5 7.155821761823774e-6 3443/1387/64135/3445/29110/3444/23586/3451/3448/3661/3439/10010/84282/3452/3446/3665/7706/3440/7189/9641/3456/3441/7186/57506/3449/2033 26 Human_herpesvirus_8_type_P R-HSA-9619483 Activation of AMPK downstream of NMDARs 26/5323 29/10654 7.30822770198432e-6 1.940127618243762e-5 7.155821761823774e-6 5563/51807/53632/10381/7846/113457/81027/79861/51422/10376/801/805/84617/10382/7277/10645/5571/347733/5562/10383/84790/5564/5565/7280/4137/808 26 Human_herpesvirus_8_type_P R-HSA-164378 PKA activation in glucagon signalling 17/5323 17/10654 7.436753128974626e-6 1.959459110948932e-5 7.227122595277925e-6 107/5567/112/5573/111/196883/115/5568/113/5566/5577/109/5575/114/108/2778/5576 17 Human_herpesvirus_8_type_P R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 17/5323 17/10654 7.436753128974626e-6 1.959459110948932e-5 7.227122595277925e-6 4790/4792/1660/3551/11035/8737/28512/8517/5970/4791/7098/81030/28511/1147/4615/4793/148022 17 Human_herpesvirus_8_type_P R-HSA-196299 Beta-catenin phosphorylation cascade 17/5323 17/10654 7.436753128974626e-6 1.959459110948932e-5 7.227122595277925e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/10023/23401/5529/5516/1499/5525/139285/5527 17 Human_herpesvirus_8_type_P R-HSA-8934593 Regulation of RUNX1 Expression and Activity 17/5323 17/10654 7.436753128974626e-6 1.959459110948932e-5 7.227122595277925e-6 27327/192669/5371/4343/865/6714/595/896/26523/5781/27161/894/57690/192670/1021/861/23112 17 Human_herpesvirus_8_type_P R-HSA-381042 PERK regulates gene expression 28/5323 32/10654 9.229640768513413e-6 2.422780701734771e-5 8.936003336365108e-6 1965/3576/3309/4801/6347/11340/468/3484/1054/8894/9451/8570/23016/118460/1968/5073/1051/4800/22926/167227/22894/440/9709/4802/1649/51013/467/54512 28 Human_herpesvirus_8_type_P R-HSA-5626467 RHO GTPases activate IQGAPs 28/5323 32/10654 9.229640768513413e-6 2.422780701734771e-5 8.936003336365108e-6 71/6249/51807/10381/7846/113457/81027/8826/5879/79861/999/10376/801/4221/805/84617/10382/7277/347733/998/10788/10383/60/84790/7280/1495/1499/808 28 Human_herpesvirus_8_type_P R-HSA-1643713 Signaling by EGFR in Cancer 23/5323 25/10654 9.373448637077346e-6 2.4288107241929697e-5 8.95824402070201e-6 5295/374/4893/5335/2885/3845/3265/7314/1839/5290/2069/6233/6464/6654/7311/1956/2549/11140/685/7316/1950/867/3320 23 Human_herpesvirus_8_type_P R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 23/5323 25/10654 9.373448637077346e-6 2.4288107241929697e-5 8.95824402070201e-6 51807/10381/10576/7846/113457/81027/10574/10693/79861/10575/10376/84617/10382/7277/347733/10383/84790/22948/7280/10694/7203/908/6950 23 Human_herpesvirus_8_type_P R-HSA-392451 G beta:gamma signalling through PI3Kgamma 23/5323 25/10654 9.373448637077346e-6 2.4288107241929697e-5 8.95824402070201e-6 2788/2782/2787/10681/2792/10000/5294/2785/2783/2784/2791/5170/2786/208/387/54331/59345/207/51764/94235/55970/2793/2790 23 Human_herpesvirus_8_type_P R-HSA-400685 Sema4D in semaphorin signaling 23/5323 25/10654 9.373448637077346e-6 2.4288107241929697e-5 8.95824402070201e-6 2909/388/2064/23365/79784/9475/4628/6093/10507/5879/389/10627/4233/387/4629/3984/4627/3985/10398/9826/4637/103910/6237 23 Human_herpesvirus_8_type_P R-HSA-5654700 FRS-mediated FGFR2 signaling 23/5323 25/10654 9.373448637077346e-6 2.4288107241929697e-5 8.95824402070201e-6 4893/2250/2885/2252/3845/3265/8823/8074/2249/2248/2247/2246/2251/5781/2263/6654/8817/10817/2254/26281/10818/2255/27006 23 Human_herpesvirus_8_type_P R-HSA-5654708 Downstream signaling of activated FGFR3 23/5323 25/10654 9.373448637077346e-6 2.4288107241929697e-5 8.95824402070201e-6 5295/4893/2250/5335/2885/3845/3265/5290/8823/8074/2249/2247/2246/5781/6464/6654/2549/8817/10817/2254/26281/10818/2261 23 Human_herpesvirus_8_type_P R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 23/5323 25/10654 9.373448637077346e-6 2.4288107241929697e-5 8.95824402070201e-6 5520/8900/28227/5518/7465/5515/993/890/983/5519/7514/2305/9133/891/4331/5347/5516/1017/994/902/9088/995/1022 23 Human_herpesvirus_8_type_P R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 44/5323 56/10654 9.708935738703837e-6 2.5111162838890254e-5 9.261813698105636e-6 79718/5469/1387/6907/11232/10499/23054/1386/85441/3054/7019/814/96764/23408/5465/4208/6604/80205/6742/801/805/4899/5442/3418/23410/4209/2553/2551/6648/211/51106/23373/2746/8841/200186/9611/23409/54205/6256/10498/1385/808/8648/10891 44 Human_herpesvirus_8_type_P R-HSA-445144 Signal transduction by L1 20/5323 21/10654 1.0175026363769632e-5 2.6172325582859e-5 9.653205036733242e-6 1459/1460/8829/4684/3688/1457/5605/3690/5879/5594/2260/7410/3685/3674/3678/3897/1956/5058/5595/5604 20 Human_herpesvirus_8_type_P R-HSA-500657 Presynaptic function of Kainate receptors 20/5323 21/10654 1.0175026363769632e-5 2.6172325582859e-5 9.653205036733242e-6 2788/5331/2782/2787/10681/2792/2785/2783/2784/2791/23236/2786/54331/59345/51764/94235/5330/55970/2793/2790 20 Human_herpesvirus_8_type_P R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 20/5323 21/10654 1.0175026363769632e-5 2.6172325582859e-5 9.653205036733242e-6 25904/55571/55835/57472/85456/29883/1263/7832/10769/7157/5325/4869/4850/246175/4848/23019/4849/9337/28984/995 20 Human_herpesvirus_8_type_P R-HSA-8953750 Transcriptional Regulation by E2F6 30/5323 35/10654 1.0659422579926227e-5 2.736826198897117e-5 1.009430528602311e-5 6045/80012/79813/11335/1869/1911/5928/10138/23512/672/6241/5888/7027/2146/1876/8726/7703/317/23429/6015/84108/5931/1111/648/23468/23269/8317/4149/5932/10919 30 Human_herpesvirus_8_type_P R-HSA-111465 Apoptotic cleavage of cellular proteins 32/5323 38/10654 1.156617828362929e-5 2.9642282049301295e-5 1.0933037856062201e-5 660/836/324/9414/4001/6709/6093/840/2934/22985/63967/841/100506658/7082/5339/28988/10134/999/5588/5580/839/1828/5747/1829/1832/4000/51765/1499/329/4137/7431/6304 32 Human_herpesvirus_8_type_P R-HSA-75067 Processing of Capped Intronless Pre-mRNA 25/5323 28/10654 1.319915864200928e-5 3.376584765328556e-5 1.245394298662311e-5 51585/81608/1477/53981/11051/8106/1478/23283/6636/10914/6635/7884/6637/10898/51692/22916/1479/79869/29894/4686/8189/10978/6634/55339/6628 25 Human_herpesvirus_8_type_P R-HSA-166658 Complement cascade 45/5323 58/10654 1.4003971388171226e-5 3.5759687374150486e-5 1.3189335933457669e-5 5199/10584/7448/717/975/732/2219/720/714/5648/727/629/722/3004/27202/1401/731/712/3075/716/1191/78989/721/725/728/4179/2147/930/1378/10747/1361/966/715/3426/2220/1991/1604/710/1675/719/713/8547/4153/5627/718 45 Human_herpesvirus_8_type_P R-HSA-1295596 Spry regulation of FGF signaling 16/5323 16/10654 1.4907137702286022e-5 3.7387420226589006e-5 1.3789696758095526e-5 8569/2885/5518/7314/5515/5594/6714/6233/5781/673/7311/5595/5516/10253/7316/867 16 Human_herpesvirus_8_type_P R-HSA-156711 Polo-like kinase mediated events 16/5323 16/10654 1.4907137702286022e-5 3.7387420226589006e-5 1.3789696758095526e-5 5928/7465/993/2305/9133/286826/891/91750/55957/5347/4605/1063/9088/2033/995/132660 16 Human_herpesvirus_8_type_P R-HSA-193639 p75NTR signals via NF-kB 16/5323 16/10654 1.4907137702286022e-5 3.7387420226589006e-5 1.3789696758095526e-5 4790/8878/4792/3654/3551/7314/8767/5970/6233/7189/7311/4804/5584/4615/7316/4803 16 Human_herpesvirus_8_type_P R-HSA-1963640 GRB2 events in ERBB2 signaling 16/5323 16/10654 1.4907137702286022e-5 3.7387420226589006e-5 1.3789696758095526e-5 4893/2064/145957/9542/2885/3845/3265/1839/2069/3084/6654/10718/1956/685/1950/2066 16 Human_herpesvirus_8_type_P R-HSA-1963642 PI3K events in ERBB2 signaling 16/5323 16/10654 1.4907137702286022e-5 3.7387420226589006e-5 1.3789696758095526e-5 5295/2064/145957/9542/2885/1839/5290/2065/2069/3084/10718/1956/2549/685/1950/2066 16 Human_herpesvirus_8_type_P R-HSA-205043 NRIF signals cell death from the nucleus 16/5323 16/10654 1.4907137702286022e-5 3.7387420226589006e-5 1.3789696758095526e-5 8878/23385/7314/5664/6233/5663/7189/83464/7311/55851/51107/4804/23421/7316/4803/5599 16 Human_herpesvirus_8_type_P R-HSA-399954 Sema3A PAK dependent Axon repulsion 16/5323 16/10654 1.4907137702286022e-5 3.7387420226589006e-5 1.3789696758095526e-5 5361/8829/2534/5362/5062/5879/1072/10371/55558/5063/3326/5058/3984/3320/91584/2242 16 Human_herpesvirus_8_type_P R-HSA-399956 CRMPs in Sema3A signaling 16/5323 16/10654 1.4907137702286022e-5 3.7387420226589006e-5 1.3789696758095526e-5 5361/8829/2534/1808/5362/1400/10371/2932/55558/10570/1020/1809/91584/56896/8851/2242 16 Human_herpesvirus_8_type_P R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 16/5323 16/10654 1.4907137702286022e-5 3.7387420226589006e-5 1.3789696758095526e-5 8454/4790/3551/7314/8945/1326/8517/6233/79155/7311/6416/1147/5604/6500/7316/23291 16 Human_herpesvirus_8_type_P R-HSA-9614657 FOXO-mediated transcription of cell death genes 16/5323 16/10654 1.4907137702286022e-5 3.7387420226589006e-5 1.3789696758095526e-5 2308/65018/356/1387/4801/604/4303/4800/10370/6794/27113/2309/10018/4802/1649/2033 16 Human_herpesvirus_8_type_P R-HSA-2122948 Activated NOTCH1 Transmits Signal to the Nucleus 27/5323 31/10654 1.628352318415762e-5 4.076675644147647e-5 1.5036105880857292e-5 182/23385/408/83737/6868/57534/28514/7314/3714/8650/102/5664/6233/5663/142678/23220/409/9148/83464/7311/55851/51107/4851/7316/54492/1840/54567 27 Human_herpesvirus_8_type_P R-HSA-3371571 HSF1-dependent transactivation 22/5323 24/10654 1.7354897875581035e-5 4.329493140238035e-5 1.596857904565407e-5 817/3305/1387/2475/3306/3312/818/3303/84335/3337/3297/57521/1410/64223/816/3326/3304/10728/815/3320/2033/2288 22 Human_herpesvirus_8_type_P R-HSA-450302 activated TAK1 mediates p38 MAPK activation 22/5323 24/10654 1.7354897875581035e-5 4.329493140238035e-5 1.596857904565407e-5 1432/3654/7334/7314/257397/5606/8767/23118/8517/9261/10454/6233/5600/5608/64127/3656/7189/7311/6885/10392/7316/7335 22 Human_herpesvirus_8_type_P R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 48/5323 63/10654 1.7416497241877234e-5 4.3371701981099594e-5 1.5996894532362324e-5 4790/5435/4792/3428/1387/22954/1660/3551/7314/11035/8737/29110/81844/28512/8517/6778/5970/3661/6233/11128/4791/9533/3665/5434/23220/7098/9208/5591/7311/81030/171568/2547/28511/1147/170506/5440/6737/1499/7520/147945/5441/51082/4615/7316/4793/5437/2033/148022 48 Human_herpesvirus_8_type_P R-HSA-187687 Signalling to ERKs 29/5323 34/10654 1.843555948193053e-5 4.582832542592978e-5 1.6902977170525856e-5 4893/5605/5898/1432/5603/2885/3845/3265/1399/5594/9261/6714/4914/5600/6300/6464/673/2889/6654/7529/5595/25759/5604/57498/10818/53358/4803/1398/5906 29 Human_herpesvirus_8_type_P R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 19/5323 20/10654 1.947261329903495e-5 4.806660861709153e-5 1.7728528820728036e-5 7321/7334/3551/7314/11035/8737/8517/7323/6233/330/7098/7189/7311/1147/7316/7335/7322/329/148022 19 Human_herpesvirus_8_type_P R-HSA-5625900 RHO GTPases activate CIT 19/5323 20/10654 1.947261329903495e-5 4.806660861709153e-5 1.7728528820728036e-5 388/79784/4628/5879/4659/389/11113/9055/5500/10627/387/4629/4627/1027/10398/4637/1742/9928/103910 19 Human_herpesvirus_8_type_P R-HSA-5627117 RHO GTPases Activate ROCKs 19/5323 20/10654 1.947261329903495e-5 4.806660861709153e-5 1.7728528820728036e-5 388/79784/9475/4628/6093/1072/4659/389/5500/10627/387/5058/4629/3984/4627/3985/10398/4637/103910 19 Human_herpesvirus_8_type_P R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 19/5323 20/10654 1.947261329903495e-5 4.806660861709153e-5 1.7728528820728036e-5 472/1387/51499/7159/637/27166/23368/7157/63970/55240/5366/84883/147923/94241/8626/7161/665/27113/581 19 Human_herpesvirus_8_type_P R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 74/5323 106/10654 2.4647361453185003e-5 6.0733515875011026e-5 2.240049626033774e-5 374/8674/4738/1212/950/10980/7037/408/10987/6456/185/30011/2885/163/11037/9185/7314/1839/161/7018/10618/1856/8322/2060/2069/1601/6453/1129/9146/6455/4074/10920/26119/29979/6233/7474/6844/1213/1211/29924/1175/6869/1173/6857/409/160/338/8218/920/2873/7311/1956/8533/8673/51138/9318/685/1080/29978/58513/7316/1950/64708/3949/867/9341/915/917/3575/6845/551/154/10254/50813 74 Human_herpesvirus_8_type_P R-HSA-111447 Activation of BAD and translocation to mitochondria 15/5323 15/10654 2.9878869256710795e-5 7.161766447051464e-5 2.641492431374235e-5 7531/10971/7533/2810/637/7534/10000/572/7532/208/7529/5533/596/207/5534 15 Human_herpesvirus_8_type_P R-HSA-2691230 Signaling by NOTCH1 HD Domain Mutants in Cancer 15/5323 15/10654 2.9878869256710795e-5 7.161766447051464e-5 2.641492431374235e-5 182/6868/57534/28514/7314/3714/102/6233/142678/9148/7311/4851/7316/54492/54567 15 Human_herpesvirus_8_type_P R-HSA-2691232 Constitutive Signaling by NOTCH1 HD Domain Mutants 15/5323 15/10654 2.9878869256710795e-5 7.161766447051464e-5 2.641492431374235e-5 182/6868/57534/28514/7314/3714/102/6233/142678/9148/7311/4851/7316/54492/54567 15 Human_herpesvirus_8_type_P R-HSA-354194 GRB2:SOS provides linkage to MAPK signaling for Integrins 15/5323 15/10654 2.9878869256710795e-5 7.161766447051464e-5 2.641492431374235e-5 5908/2244/3690/2885/7094/6714/2335/2266/2243/5747/3674/6654/7450/54518/5906 15 Human_herpesvirus_8_type_P R-HSA-372708 p130Cas linkage to MAPK signaling for integrins 15/5323 15/10654 2.9878869256710795e-5 7.161766447051464e-5 2.641492431374235e-5 5908/2244/3690/9564/7094/6714/2335/2266/2243/5747/3674/7450/54518/1398/5906 15 Human_herpesvirus_8_type_P R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 15/5323 15/10654 2.9878869256710795e-5 7.161766447051464e-5 2.641492431374235e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Human_herpesvirus_8_type_P R-HSA-5099900 WNT5A-dependent internalization of FZD4 15/5323 15/10654 2.9878869256710795e-5 7.161766447051464e-5 2.641492431374235e-5 5579/5578/1212/5582/163/161/1856/8322/7474/1213/1211/1175/1173/409/160 15 Human_herpesvirus_8_type_P R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 15/5323 15/10654 2.9878869256710795e-5 7.161766447051464e-5 2.641492431374235e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Human_herpesvirus_8_type_P R-HSA-5358508 Mismatch Repair 15/5323 15/10654 2.9878869256710795e-5 7.161766447051464e-5 2.641492431374235e-5 4436/9156/6117/10714/4437/6118/3978/5424/2956/4292/5425/5111/6119/57804/5395 15 Human_herpesvirus_8_type_P R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 15/5323 15/10654 2.9878869256710795e-5 7.161766447051464e-5 2.641492431374235e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Human_herpesvirus_8_type_P R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 15/5323 15/10654 2.9878869256710795e-5 7.161766447051464e-5 2.641492431374235e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Human_herpesvirus_8_type_P R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 15/5323 15/10654 2.9878869256710795e-5 7.161766447051464e-5 2.641492431374235e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Human_herpesvirus_8_type_P R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 15/5323 15/10654 2.9878869256710795e-5 7.161766447051464e-5 2.641492431374235e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Human_herpesvirus_8_type_P R-HSA-5637810 Constitutive Signaling by EGFRvIII 15/5323 15/10654 2.9878869256710795e-5 7.161766447051464e-5 2.641492431374235e-5 5295/4893/5335/2885/3845/3265/5290/6464/6654/1956/2549/11140/1950/867/3320 15 Human_herpesvirus_8_type_P R-HSA-5637812 Signaling by EGFRvIII in Cancer 15/5323 15/10654 2.9878869256710795e-5 7.161766447051464e-5 2.641492431374235e-5 5295/4893/5335/2885/3845/3265/5290/6464/6654/1956/2549/11140/1950/867/3320 15 Human_herpesvirus_8_type_P R-HSA-69183 Processive synthesis on the lagging strand 15/5323 15/10654 2.9878869256710795e-5 7.161766447051464e-5 2.641492431374235e-5 2237/1763/5422/6117/10714/5558/6118/3978/5557/23649/5424/5425/5111/6119/57804 15 Human_herpesvirus_8_type_P R-HSA-5654695 PI-3K cascade:FGFR2 21/5323 23/10654 3.2023432696690125e-5 7.649740204455518e-5 2.821473026444149e-5 5295/2250/2885/2252/5290/8823/8074/2249/2248/2247/2246/2251/5781/2263/2549/8817/2254/26281/10818/2255/27006 21 Human_herpesvirus_8_type_P R-HSA-5654699 SHC-mediated cascade:FGFR2 21/5323 23/10654 3.2023432696690125e-5 7.649740204455518e-5 2.821473026444149e-5 4893/2250/2885/2252/3845/3265/8823/8074/2249/2248/2247/2246/2251/6464/2263/6654/8817/2254/26281/2255/27006 21 Human_herpesvirus_8_type_P R-HSA-110320 Translesion Synthesis by POLH 18/5323 19/10654 3.7177987944865375e-5 8.82115160850347e-5 3.253527657196882e-5 5982/25898/6117/55666/7314/6118/5985/5984/6233/5111/6119/83932/5429/7311/5983/7316/7415/5981 18 Human_herpesvirus_8_type_P R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 18/5323 19/10654 3.7177987944865375e-5 8.82115160850347e-5 3.253527657196882e-5 1869/4609/5928/990/7027/7153/5934/993/286826/5111/91750/1874/55957/4149/1875/5933/3065/132660 18 Human_herpesvirus_8_type_P R-HSA-392851 Prostacyclin signalling through prostacyclin receptor 18/5323 19/10654 3.7177987944865375e-5 8.82115160850347e-5 3.253527657196882e-5 2788/2782/2787/10681/2792/2785/2783/2784/2791/2786/54331/59345/51764/94235/55970/2778/2793/2790 18 Human_herpesvirus_8_type_P R-HSA-6804760 Regulation of TP53 Activity through Methylation 18/5323 19/10654 3.7177987944865375e-5 8.82115160850347e-5 3.253527657196882e-5 133383/11200/472/79813/4194/56950/7314/7157/6233/10419/26013/7311/7316/2033/91875/133746/10919/4193 18 Human_herpesvirus_8_type_P R-HSA-70171 Glycolysis 52/5323 71/10654 5.196791643743818e-5 1.230957212583763e-4 4.54017061911342e-5 23165/7167/348995/57122/3099/23511/23279/23225/9972/5518/8021/2026/55746/5515/2597/5567/10762/5528/79902/5519/9883/226/2821/5208/6396/129401/230/4928/5903/55706/7175/5568/4927/5566/2023/669/8086/5207/5516/9631/5315/79023/23636/5214/53371/5230/3098/9688/5210/5209/5213/8480 52 Human_herpesvirus_8_type_P R-HSA-8941326 RUNX2 regulates bone development 27/5323 32/10654 5.437448822863677e-5 1.2857967216418814e-4 4.742436567309674e-5 5925/9759/10413/4089/121340/25/5594/3280/10013/2737/865/6714/7525/10432/4091/1277/2736/23493/367/860/5595/8841/23462/4086/4094/23314/25937 27 Human_herpesvirus_8_type_P R-HSA-2979096 NOTCH2 Activation and Transmission of Signal to the Nucleus 20/5323 22/10654 5.887259164156454e-5 1.3416137919570662e-4 4.94830807941371e-5 182/23385/4853/57534/28514/7314/3714/102/5664/6233/5663/142678/9148/83464/7311/55851/51107/7316/54492/54567 20 Human_herpesvirus_8_type_P R-HSA-5654712 FRS-mediated FGFR4 signaling 20/5323 22/10654 5.887259164156454e-5 1.3416137919570662e-4 4.94830807941371e-5 4893/9965/2264/2885/3845/3265/8823/8074/2249/2247/2246/2251/5781/6654/8817/10817/2254/152831/26281/10818 20 Human_herpesvirus_8_type_P R-HSA-5655332 Signaling by FGFR3 in disease 20/5323 22/10654 5.887259164156454e-5 1.3416137919570662e-4 4.94830807941371e-5 5295/4893/2250/5335/2885/3845/3265/5290/8823/8074/2249/2247/2246/6654/2549/8817/2254/26281/10818/2261 20 Human_herpesvirus_8_type_P R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 20/5323 22/10654 5.887259164156454e-5 1.3416137919570662e-4 4.94830807941371e-5 5295/4893/2250/5335/2885/3845/3265/5290/8823/8074/2249/2247/2246/6654/2549/8817/2254/26281/10818/2261 20 Human_herpesvirus_8_type_P R-HSA-9613829 Chaperone Mediated Autophagy 20/5323 22/10654 5.887259164156454e-5 1.3416137919570662e-4 4.94830807941371e-5 2670/1915/5116/3043/3920/3312/11315/7314/10013/123/6233/1068/3326/7311/1080/6035/7316/10226/3320/7431 20 Human_herpesvirus_8_type_P R-HSA-1250347 SHC1 events in ERBB4 signaling 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 4893/145957/9542/2885/3845/3265/1839/2069/6464/3084/6654/10718/685/2066 14 Human_herpesvirus_8_type_P R-HSA-162594 Early Phase of HIV Life Cycle 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 2237/7852/3981/3836/7518/3978/11168/5478/920/2547/1234/3159/7520/8815 14 Human_herpesvirus_8_type_P R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 5861/2801/5594/983/8548/8615/9133/891/81876/5347/5595/5862/26003/64689 14 Human_herpesvirus_8_type_P R-HSA-166786 Creation of C4 and C2 activators 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 10584/2219/714/5648/1401/712/716/78989/10747/715/2220/713/8547/4153 14 Human_herpesvirus_8_type_P R-HSA-169893 Prolonged ERK activation events 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 5605/1399/5594/4914/673/2889/7529/5595/5604/57498/10818/4803/1398/5906 14 Human_herpesvirus_8_type_P R-HSA-174411 Polymerase switching on the C-strand of the telomere 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 5982/5422/10714/5558/5557/5985/5984/23649/5424/5425/5111/5983/57804/5981 14 Human_herpesvirus_8_type_P R-HSA-198323 AKT phosphorylates targets in the cytosol 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 84335/7249/2932/10000/2931/23608/572/208/1147/842/207/1027/1026/4193 14 Human_herpesvirus_8_type_P R-HSA-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 107/5567/5573/5613/801/805/5568/5566/5577/5575/114/5576/1385/808 14 Human_herpesvirus_8_type_P R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Human_herpesvirus_8_type_P R-HSA-4839744 truncated APC mutants destabilize the destruction complex 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Human_herpesvirus_8_type_P R-HSA-4839748 AMER1 mutants destabilize the destruction complex 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Human_herpesvirus_8_type_P R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 4436/9156/6117/10714/6118/3978/5424/2956/4292/5425/5111/6119/57804/5395 14 Human_herpesvirus_8_type_P R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 4436/9156/6117/10714/4437/6118/3978/5424/4292/5425/5111/6119/57804/5395 14 Human_herpesvirus_8_type_P R-HSA-5467337 APC truncation mutants have impaired AXIN binding 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Human_herpesvirus_8_type_P R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Human_herpesvirus_8_type_P R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Human_herpesvirus_8_type_P R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 9134/57060/1869/8900/144455/898/890/7157/79733/1820/1017/25946/1027/1026 14 Human_herpesvirus_8_type_P R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 7159/51230/23368/5458/10000/7157/5457/54971/8626/208/7161/25946/207/10848 14 Human_herpesvirus_8_type_P R-HSA-69091 Polymerase switching 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 5982/5422/10714/5558/5557/5985/5984/23649/5424/5425/5111/5983/57804/5981 14 Human_herpesvirus_8_type_P R-HSA-69109 Leading Strand Synthesis 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 5982/5422/10714/5558/5557/5985/5984/23649/5424/5425/5111/5983/57804/5981 14 Human_herpesvirus_8_type_P R-HSA-69166 Removal of the Flap Intermediate 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 2237/1763/5422/6117/10714/5558/6118/5557/23649/5424/5425/5111/6119/57804 14 Human_herpesvirus_8_type_P R-HSA-877312 Regulation of IFNG signaling 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 5777/5770/9021/3459/3717/3458/5781/8554/6772/8651/5771/3716/3460/7341 14 Human_herpesvirus_8_type_P R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 4893/2909/5753/9564/3845/3265/5829/5879/5921/1793/387/63916/1398/9844 14 Human_herpesvirus_8_type_P R-HSA-8941856 RUNX3 regulates NOTCH signaling 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 182/22938/1387/9794/2648/55534/3280/84441/8850/864/10046/4851/2033/3516 14 Human_herpesvirus_8_type_P R-HSA-8983432 Interleukin-15 signaling 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 6776/2885/9846/3600/3718/6777/6464/6774/6654/3716/6655/3561/3560/3601 14 Human_herpesvirus_8_type_P R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 79718/9612/6907/4204/814/801/805/5566/25942/8841/9611/2874/3065/808 14 Human_herpesvirus_8_type_P R-HSA-9005895 Pervasive developmental disorders 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 79718/9612/6907/4204/814/801/805/5566/25942/8841/9611/2874/3065/808 14 Human_herpesvirus_8_type_P R-HSA-9027284 Erythropoietin activates RAS 14/5323 14/10654 5.98815537561505e-5 1.3416137919570662e-4 4.94830807941371e-5 4893/3717/2885/2056/8660/3845/3265/1399/2057/7409/6464/2889/4067/6654 14 Human_herpesvirus_8_type_P R-HSA-75153 Apoptotic execution phase 40/5323 52/10654 6.015825246810834e-5 1.3456702897079244e-4 4.9632697626604334e-5 10059/660/836/324/9414/4001/3836/6709/6093/840/5062/2934/22985/63967/841/100506658/7082/5339/28988/10134/999/5588/5580/839/1828/5747/1829/1832/3148/4000/3837/1676/51765/1499/3146/329/4137/1677/7431/6304 40 Human_herpesvirus_8_type_P R-HSA-1368082 RORA activates gene expression 17/5323 18/10654 7.079772199421713e-5 1.5761454880674605e-4 5.813337265681054e-5 79718/5469/1387/6907/10499/23054/85441/96764/5465/6604/80205/1374/6720/2033/6256/10498/8648 17 Human_herpesvirus_8_type_P R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 17/5323 18/10654 7.079772199421713e-5 1.5761454880674605e-4 5.813337265681054e-5 5295/11052/613/6776/11064/2885/9846/7750/8805/26127/5290/399687/6777/1523/9208/6774/6772 17 Human_herpesvirus_8_type_P R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 17/5323 18/10654 7.079772199421713e-5 1.5761454880674605e-4 5.813337265681054e-5 2810/6790/1647/7027/5934/983/7157/891/5111/1874/25946/5933/2033/995/10498/581/3276 17 Human_herpesvirus_8_type_P R-HSA-429947 Deadenylation of mRNA 22/5323 25/10654 7.588552562460852e-5 1.6840841412275108e-4 6.211450129990371e-5 26986/25904/1973/55571/57472/85456/29883/1981/1977/9924/5073/4850/255967/246175/4848/23019/1975/1974/4849/10605/9337/9775 22 Human_herpesvirus_8_type_P R-HSA-937041 IKK complex recruitment mediated by RIP1 22/5323 25/10654 7.588552562460852e-5 1.6840841412275108e-4 6.211450129990371e-5 7321/929/7334/3551/7314/11035/8737/8517/7323/6233/330/7189/7311/23643/1147/7099/7316/7335/7322/329/353376/148022 22 Human_herpesvirus_8_type_P R-HSA-75893 TNF signaling 34/5323 43/10654 8.106642255052475e-5 1.7962276618675328e-4 6.625071913370693e-5 7124/7375/9530/10616/6868/1540/3551/7314/257397/81858/8737/55072/23118/841/8517/8887/7128/10454/6233/8772/331/8717/330/27005/7311/1147/7186/56957/6885/7316/7132/329/9099/7185 34 Human_herpesvirus_8_type_P R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 26/5323 31/10654 9.267399357636132e-5 2.0437665981495358e-4 7.538076032526997e-5 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/9631/79023/23636/53371/9688/8480 26 Human_herpesvirus_8_type_P R-HSA-182971 EGFR downregulation 26/5323 31/10654 9.267399357636132e-5 2.0437665981495358e-4 7.538076032526997e-5 374/6456/30011/2885/8874/10252/7314/1839/2060/2069/9146/6455/6233/29924/5782/998/7311/1956/10253/685/58513/7316/1950/867/5774/10254 26 Human_herpesvirus_8_type_P R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 26/5323 31/10654 9.267399357636132e-5 2.0437665981495358e-4 7.538076032526997e-5 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/9631/79023/23636/53371/9688/8480 26 Human_herpesvirus_8_type_P R-HSA-4791275 Signaling by WNT in cancer 28/5323 34/10654 9.381782712685717e-5 2.0657540339200005e-4 7.619172847959903e-5 27123/5526/1452/324/8312/5518/80351/5515/8322/5528/89780/8323/5519/2932/4040/7855/4041/8658/6934/5529/5516/1487/1499/5525/139285/54894/5527/1488 28 Human_herpesvirus_8_type_P R-HSA-373760 L1CAM interactions 80/5323 119/10654 9.619671427397512e-5 2.1148246403669216e-4 7.800161206754892e-5 9252/6711/71/7430/1459/51807/1785/1460/10381/8829/4684/3688/1457/285643/5605/7846/113457/3690/1808/81027/6456/6709/163/6196/1759/27255/6197/8986/3312/100133941/5879/6331/6900/161/79861/5594/6327/2260/8650/6714/10376/6195/214/7410/3685/1213/1211/1175/1173/84617/6712/3674/10382/7277/3678/4478/160/3912/26052/27330/347733/6386/1641/2048/3897/10383/24137/1956/60/84790/5058/7280/5595/5604/10048/3915/57731/1742/287/288 80 Human_herpesvirus_8_type_P R-HSA-416572 Sema4D induced cell migration and growth-cone collapse 19/5323 21/10654 1.0779968918405529e-4 2.3588516746806502e-4 8.700212289062661e-5 388/2064/23365/79784/9475/4628/6093/10507/389/10627/387/4629/3984/4627/3985/10398/9826/4637/103910 19 Human_herpesvirus_8_type_P R-HSA-5621575 CD209 (DC-SIGN) signaling 19/5323 21/10654 1.0779968918405529e-4 2.3588516746806502e-4 8.700212289062661e-5 9252/4893/4790/1387/2534/5894/3845/3265/5062/5567/5970/5568/5566/4067/5063/30835/5971/5058/2033 19 Human_herpesvirus_8_type_P R-HSA-9008059 Interleukin-37 signaling 19/5323 21/10654 1.0779968918405529e-4 2.3588516746806502e-4 8.700212289062661e-5 834/5777/26469/5783/27178/59307/4088/84867/29110/8809/5781/5782/6774/5780/5771/5778/25930/5775/5784 19 Human_herpesvirus_8_type_P R-HSA-429914 Deadenylation-dependent mRNA decay 42/5323 56/10654 1.1055589230204328e-4 2.415405907903337e-4 8.908802697761907e-5 80153/26986/28960/25904/1973/55571/11340/57472/85456/29883/80349/51690/11157/1981/1977/23016/118460/9924/5073/27258/4850/255967/57819/246175/4848/23019/23658/1975/1974/167227/22894/1656/27257/4849/25804/10605/9337/55802/51013/196513/9775/54512 42 Human_herpesvirus_8_type_P R-HSA-202670 ERKs are inactivated 13/5323 13/10654 1.1999992721642164e-4 2.5935468140323386e-4 9.565844307170489e-5 1848/5518/51231/5515/1849/5594/5528/5519/5598/1846/5595/5516/1845 13 Human_herpesvirus_8_type_P R-HSA-209543 p75NTR recruits signalling complexes 13/5323 13/10654 1.1999992721642164e-4 2.5935468140323386e-4 9.565844307170489e-5 8878/3654/3551/7314/8767/6233/7189/7311/4804/5584/4615/7316/4803 13 Human_herpesvirus_8_type_P R-HSA-209560 NF-kB is activated and signals survival 13/5323 13/10654 1.1999992721642164e-4 2.5935468140323386e-4 9.565844307170489e-5 4790/8878/4792/3654/3551/7314/5970/6233/7189/7311/4804/7316/4803 13 Human_herpesvirus_8_type_P R-HSA-5357786 TNFR1-induced proapoptotic signaling 13/5323 13/10654 1.1999992721642164e-4 2.5935468140323386e-4 9.565844307170489e-5 7124/7375/1540/8737/841/7128/8772/8717/27005/7186/56957/7132/9099 13 Human_herpesvirus_8_type_P R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13/5323 13/10654 1.1999992721642164e-4 2.5935468140323386e-4 9.565844307170489e-5 7531/10971/7533/2810/11200/7465/7534/983/7532/891/1111/7529/995 13 Human_herpesvirus_8_type_P R-HSA-879415 Advanced glycosylation endproduct receptor signaling 13/5323 13/10654 1.1999992721642164e-4 2.5935468140323386e-4 9.565844307170489e-5 177/6283/5594/351/1650/830/3958/829/5595/5589/3146/6288/6285 13 Human_herpesvirus_8_type_P R-HSA-8847993 ERBB2 Activates PTK6 Signaling 13/5323 13/10654 1.1999992721642164e-4 2.5935468140323386e-4 9.565844307170489e-5 2064/5753/145957/9542/1839/2065/2069/3084/10718/1956/685/1950/2066 13 Human_herpesvirus_8_type_P R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 16/5323 17/10654 1.3443329087526907e-4 2.8759843589885544e-4 1.0607565847314986e-4 356/929/8737/841/8797/8772/8717/8743/8837/8795/23643/7186/355/7099/353376/148022 16 Human_herpesvirus_8_type_P R-HSA-432142 Platelet sensitization by LDL 16/5323 17/10654 1.3443329087526907e-4 2.8759843589885544e-4 1.0607565847314986e-4 5777/5526/5175/2268/1432/5518/5515/5528/5519/5781/338/5529/5516/5321/5525/5527 16 Human_herpesvirus_8_type_P R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 16/5323 17/10654 1.3443329087526907e-4 2.8759843589885544e-4 1.0607565847314986e-4 2308/857/2290/57060/2660/4089/1647/4088/5934/4303/901/9314/4087/2309/1027/1026 16 Human_herpesvirus_8_type_P R-HSA-203927 MicroRNA (miRNA) biogenesis 21/5323 24/10654 1.3470317644445325e-4 2.8759843589885544e-4 1.0607565847314986e-4 5431/5435/5433/5439/192669/29102/5438/54487/8575/26523/23405/5434/5436/5901/5432/27161/5440/5430/5441/192670/5437 21 Human_herpesvirus_8_type_P R-HSA-452723 Transcriptional regulation of pluripotent stem cells 21/5323 24/10654 1.3470317644445325e-4 2.8759843589885544e-4 1.0607565847314986e-4 64344/79727/6657/55211/4089/84891/2516/5460/2041/5087/2247/63978/6774/9314/79923/4087/2034/7547/6997/27086/57167 21 Human_herpesvirus_8_type_P R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 21/5323 24/10654 1.3470317644445325e-4 2.8759843589885544e-4 1.0607565847314986e-4 5579/10811/5578/6280/1432/5879/5594/5880/5580/1535/5600/30849/4688/5590/653361/6279/5595/5289/4689/5300/1536 21 Human_herpesvirus_8_type_P R-HSA-8940973 RUNX2 regulates osteoblast differentiation 21/5323 24/10654 1.3470317644445325e-4 2.8759843589885544e-4 1.0607565847314986e-4 5925/10413/121340/25/5594/3280/10013/2737/865/6714/7525/1277/23493/367/860/5595/8841/23462/4094/23314/25937 21 Human_herpesvirus_8_type_P R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 21/5323 24/10654 1.3470317644445325e-4 2.8759843589885544e-4 1.0607565847314986e-4 374/1839/5594/2069/10000/595/7514/2353/5747/208/1956/5595/596/685/2309/207/6722/1027/1950/2002/1385 21 Human_herpesvirus_8_type_P R-HSA-4551638 SUMOylation of chromatin organization proteins 51/5323 71/10654 1.4136317045968866e-4 3.013605770254272e-4 1.1115158379047292e-4 1912/23165/6045/80012/348995/6613/57122/23511/9759/1911/23279/23225/23512/57332/1107/9972/6612/8021/55746/10762/79902/9883/84733/3066/9063/6396/129401/7703/9189/6015/8554/4928/5903/55706/7175/8535/4927/8086/7329/648/23468/9631/79023/23636/53371/9688/7341/3065/23314/6304/8480 51 Human_herpesvirus_8_type_P R-HSA-167287 HIV elongation arrest and recovery 29/5323 36/10654 1.5025617725148368e-4 3.182367951324182e-4 1.1737608199624598e-4 5431/5435/5433/5439/11198/904/51497/5438/1025/7936/6829/25920/2963/5434/5436/2962/8812/905/5432/6917/5440/5430/6749/5441/7469/9150/5437/6827/8178 29 Human_herpesvirus_8_type_P R-HSA-167290 Pausing and recovery of HIV elongation 29/5323 36/10654 1.5025617725148368e-4 3.182367951324182e-4 1.1737608199624598e-4 5431/5435/5433/5439/11198/904/51497/5438/1025/7936/6829/25920/2963/5434/5436/2962/8812/905/5432/6917/5440/5430/6749/5441/7469/9150/5437/6827/8178 29 Human_herpesvirus_8_type_P R-HSA-1368108 BMAL1:CLOCK,NPAS2 activates circadian gene expression 23/5323 27/10654 1.5063660665116596e-4 3.182367951324182e-4 1.1737608199624598e-4 79718/5469/1387/6907/2155/10499/23054/9575/85441/96764/5054/5465/6604/80205/56938/406/8553/4862/79365/6256/10498/8648/551 23 Human_herpesvirus_8_type_P R-HSA-354192 Integrin alphaIIb beta3 signaling 23/5323 27/10654 1.5063660665116596e-4 3.182367951324182e-4 1.1737608199624598e-4 5770/5908/2244/3690/2885/9564/7094/6714/2335/1445/2266/2243/5170/6464/5747/3674/6850/6654/7450/207/54518/1398/5906 23 Human_herpesvirus_8_type_P R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress 23/5323 27/10654 1.5063660665116596e-4 3.182367951324182e-4 1.1737608199624598e-4 3576/4801/6347/11340/468/3484/1054/8570/23016/118460/5073/1051/4800/22926/167227/22894/440/9709/4802/1649/51013/467/54512 23 Human_herpesvirus_8_type_P R-HSA-9006921 Integrin signaling 23/5323 27/10654 1.5063660665116596e-4 3.182367951324182e-4 1.1737608199624598e-4 5770/5908/2244/3690/2885/9564/7094/6714/2335/1445/2266/2243/5170/6464/5747/3674/6850/6654/7450/207/54518/1398/5906 23 Human_herpesvirus_8_type_P R-HSA-5357905 Regulation of TNFR1 signaling 27/5323 33/10654 1.5623727857666777e-4 3.2957398944133664e-4 1.2155760804592004e-4 7124/7375/10616/1540/3551/7314/81858/8737/55072/841/8517/8887/7128/6233/331/8717/330/27005/7311/1147/7186/56957/7316/7132/329/9099/7185 27 Human_herpesvirus_8_type_P R-HSA-525793 Myogenesis 25/5323 30/10654 1.5708202812397367e-4 3.308599005545374e-4 1.2203189389397895e-4 9043/663/4617/1432/25/1496/4208/4654/5600/6300/5608/6929/91653/6938/4209/1002/1000/998/6925/1495/1499/50937/4205/4207/1013 25 Human_herpesvirus_8_type_P R-HSA-74752 Signaling by Insulin receptor 55/5323 78/10654 1.7544793625838865e-4 3.689913995748174e-4 1.3609603111538923e-4 5295/3643/4893/2250/5291/535/9965/2264/3630/2885/8660/9846/2252/3845/3265/54106/5290/3667/8823/9550/9114/5594/8074/57761/2260/2249/2248/2247/529/533/2246/2251/523/5781/30849/5170/6464/2322/527/2263/208/6654/2549/5595/8817/2254/152831/5289/26281/10818/2261/2255/27006/5296/51382 55 Human_herpesvirus_8_type_P R-HSA-445717 Aquaporin-mediated transport 39/5323 52/10654 1.9440854792366868e-4 4.0825795063970425e-4 1.5057881245305368e-4 2788/107/2782/2787/22841/5567/10681/112/5573/111/2792/2785/2783/2784/196883/115/2791/5568/359/113/5566/2786/5577/109/54331/5575/59345/51764/94235/114/108/8766/55970/2778/2793/5576/4645/551/2790 39 Human_herpesvirus_8_type_P R-HSA-5654706 FRS-mediated FGFR3 signaling 18/5323 20/10654 1.9652635975733927e-4 4.102560655468492e-4 1.5131578222765622e-4 4893/2250/2885/3845/3265/8823/8074/2249/2247/2246/5781/6654/8817/10817/2254/26281/10818/2261 18 Human_herpesvirus_8_type_P R-HSA-5654719 SHC-mediated cascade:FGFR4 18/5323 20/10654 1.9652635975733927e-4 4.102560655468492e-4 1.5131578222765622e-4 4893/9965/2264/2885/3845/3265/8823/8074/2249/2247/2246/2251/6464/6654/8817/2254/152831/26281 18 Human_herpesvirus_8_type_P R-HSA-5654720 PI-3K cascade:FGFR4 18/5323 20/10654 1.9652635975733927e-4 4.102560655468492e-4 1.5131578222765622e-4 5295/9965/2264/2885/5290/8823/8074/2249/2247/2246/2251/5781/2549/8817/2254/152831/26281/10818 18 Human_herpesvirus_8_type_P R-HSA-622312 Inflammasomes 18/5323 20/10654 1.9652635975733927e-4 4.102560655468492e-4 1.5131578222765622e-4 834/4790/7295/29108/10628/5970/5027/598/4791/351/3326/4210/114548/9447/596/10910/58484/22861 18 Human_herpesvirus_8_type_P R-HSA-2559583 Cellular Senescence 122/5323 195/10654 2.3622264067152206e-4 4.896029048712983e-4 1.8058147765050695e-4 1912/3725/9134/2077/11065/4790/7321/6045/8697/27327/80012/7295/5925/472/79813/3576/2114/1869/1911/4194/1031/5928/1432/4683/23512/57332/192669/8900/51529/4001/29945/8091/51434/1032/1030/6196/4343/6197/29882/4217/54386/3569/7314/996/7014/5601/5606/7027/2146/5594/898/890/5970/9261/6667/51433/5598/84733/119504/6195/7157/7324/64682/6233/2353/8726/5600/26523/5608/6015/1019/9448/246184/1029/8535/5931/7013/1051/50488/8881/6774/3552/10524/5602/10393/1870/51343/7311/25906/3397/57634/648/23466/3456/2113/6416/23523/5595/1017/25913/3159/7290/10111/57690/1027/192670/3490/8550/29855/7316/1026/1871/65057/1021/25842/23135/23112/5609/5599/10919/4193/23043 122 Human_herpesvirus_8_type_P R-HSA-5654693 FRS-mediated FGFR1 signaling 20/5323 23/10654 2.3786698460739596e-4 4.896029048712983e-4 1.8058147765050695e-4 4893/2250/2885/3845/3265/8074/2260/2249/2248/2247/2246/2251/5781/6654/10817/2254/26281/10818/2255/27006 20 Human_herpesvirus_8_type_P R-HSA-111932 CaMK IV-mediated phosphorylation of CREB 12/5323 12/10654 2.4045174645775916e-4 4.896029048712983e-4 1.8058147765050695e-4 817/814/818/801/805/3838/10645/84254/816/815/1385/808 12 Human_herpesvirus_8_type_P R-HSA-170968 Frs2-mediated activation 12/5323 12/10654 2.4045174645775916e-4 4.896029048712983e-4 1.8058147765050695e-4 5605/1399/5594/4914/673/2889/7529/5595/5604/10818/4803/5906 12 Human_herpesvirus_8_type_P R-HSA-176974 Unwinding of DNA 12/5323 12/10654 2.4045174645775916e-4 4.896029048712983e-4 1.8058147765050695e-4 4174/84515/84296/64785/4175/4172/8318/4173/51659/4176/9837/4171 12 Human_herpesvirus_8_type_P R-HSA-190873 Gap junction degradation 12/5323 12/10654 2.4045174645775916e-4 4.896029048712983e-4 1.8058147765050695e-4 71/1212/1785/2697/1759/4646/1601/1213/1211/1173/8218/60 12 Human_herpesvirus_8_type_P R-HSA-2029481 FCGR activation 12/5323 12/10654 2.4045174645775916e-4 4.896029048712983e-4 1.8058147765050695e-4 2268/2534/6714/7525/2214/2209/6850/4067/919/3055/917/2212 12 Human_herpesvirus_8_type_P R-HSA-210990 PECAM1 interactions 12/5323 12/10654 2.4045174645775916e-4 4.896029048712983e-4 1.8058147765050695e-4 5777/5335/5175/2534/3690/3635/6714/7525/3685/3932/5781/4067 12 Human_herpesvirus_8_type_P R-HSA-2197563 NOTCH2 intracellular domain regulates transcription 12/5323 12/10654 2.4045174645775916e-4 4.896029048712983e-4 1.8058147765050695e-4 4853/9794/388585/55534/3280/84441/3002/10046/2208/2033/1385/3516 12 Human_herpesvirus_8_type_P R-HSA-381033 ATF6 (ATF6-alpha) activates chaperones 12/5323 12/10654 2.4045174645775916e-4 4.896029048712983e-4 1.8058147765050695e-4 811/3309/4801/8720/468/7184/7494/4800/22926/4802/1649/51360 12 Human_herpesvirus_8_type_P R-HSA-389359 CD28 dependent Vav1 pathway 12/5323 12/10654 2.4045174645775916e-4 4.896029048712983e-4 1.8058147765050695e-4 941/2534/2885/5062/5879/7409/3932/940/5063/998/5058/942 12 Human_herpesvirus_8_type_P R-HSA-417957 P2Y receptors 12/5323 12/10654 2.4045174645775916e-4 4.896029048712983e-4 1.8058147765050695e-4 10161/64805/2840/5028/5029/53829/27334/9934/5032/5031/5030/2846 12 Human_herpesvirus_8_type_P R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 12/5323 12/10654 2.4045174645775916e-4 4.896029048712983e-4 1.8058147765050695e-4 7159/23368/8797/7157/8626/7161/8795/8793/3486/355/8794/124446 12 Human_herpesvirus_8_type_P R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 12/5323 12/10654 2.4045174645775916e-4 4.896029048712983e-4 1.8058147765050695e-4 7187/7314/29110/3661/6233/10010/3665/7098/7311/9641/7316/148022 12 Human_herpesvirus_8_type_P R-HSA-9020558 Interleukin-2 signaling 12/5323 12/10654 2.4045174645775916e-4 4.896029048712983e-4 1.8058147765050695e-4 6776/3558/3718/3932/6777/6464/6850/3716/2185/3561/3560/3559 12 Human_herpesvirus_8_type_P R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12/5323 12/10654 2.4045174645775916e-4 4.896029048712983e-4 1.8058147765050695e-4 64135/3551/8737/841/8517/23586/84282/8772/7706/843/1147/57506 12 Human_herpesvirus_8_type_P R-HSA-9634600 Regulation of glycolysis by fructose 2,6-bisphosphate metabolism 12/5323 12/10654 2.4045174645775916e-4 4.896029048712983e-4 1.8058147765050695e-4 5518/5515/5567/5528/5519/5208/5568/5566/5207/5516/5210/5209 12 Human_herpesvirus_8_type_P R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 15/5323 16/10654 2.5445484257308236e-4 5.15133760432125e-4 1.8999808767668252e-4 1869/5928/7027/5934/890/983/286826/91750/1874/55957/4605/1875/5933/3065/132660 15 Human_herpesvirus_8_type_P R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 15/5323 16/10654 2.5445484257308236e-4 5.15133760432125e-4 1.8999808767668252e-4 7040/7314/50848/7046/2280/6233/57530/5590/7048/7311/387/57154/50855/7316/56288 15 Human_herpesvirus_8_type_P R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 15/5323 16/10654 2.5445484257308236e-4 5.15133760432125e-4 1.8999808767668252e-4 5295/5291/2534/2885/9846/5290/5170/6464/2205/2206/6850/4067/6654/5296/2207 15 Human_herpesvirus_8_type_P R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 15/5323 16/10654 2.5445484257308236e-4 5.15133760432125e-4 1.8999808767668252e-4 929/7314/257397/23118/10454/6233/3656/7189/7311/23643/6885/7099/7316/353376/148022 15 Human_herpesvirus_8_type_P R-HSA-5205647 Mitophagy 24/5323 29/10654 2.646921053451221e-4 5.343210792260928e-4 1.9707499499380078e-4 9927/65018/1459/9140/8878/1460/9474/1457/84557/7314/139341/192111/6714/8408/55669/6233/9804/51001/7416/7311/10452/7316/81631/54543 24 Human_herpesvirus_8_type_P R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 24/5323 29/10654 2.646921053451221e-4 5.343210792260928e-4 1.9707499499380078e-4 2308/84676/4089/4088/3630/56729/847/3484/5443/3066/5105/4303/23410/4287/2908/4852/6648/4087/25942/2309/6720/3065/91584/10891 24 Human_herpesvirus_8_type_P R-HSA-202430 Translocation of ZAP-70 to Immunological synapse 17/5323 19/10654 3.5656546141370535e-4 7.177218944335958e-4 2.6471918150283377e-4 3115/3113/3117/26191/3127/3126/916/3932/3120/3123/3122/920/3125/3119/919/915/917 17 Human_herpesvirus_8_type_P R-HSA-5686938 Regulation of TLR by endogenous ligand 17/5323 19/10654 3.5656546141370535e-4 7.177218944335958e-4 2.6471918150283377e-4 6280/10333/2244/929/6271/7096/2266/2243/653509/338/6279/23643/7099/3146/948/7097/3929 17 Human_herpesvirus_8_type_P R-HSA-3299685 Detoxification of Reactive Oxygen Species 29/5323 37/10654 3.62886148590866e-4 7.294011586676405e-4 2.6902687406811575e-4 7295/7001/7296/2876/2936/847/2877/1535/4688/653361/25828/6648/79400/257202/2880/2878/10935/54205/9588/6647/2882/493869/50507/4689/5052/1536/5034/318/2950 29 Human_herpesvirus_8_type_P R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 27/5323 34/10654 3.9699801988307535e-4 7.956926125006938e-4 2.934773186420096e-4 5431/5435/5433/5439/11198/904/51497/5438/1025/7936/6829/25920/2963/5434/5436/2962/5432/6917/5440/5430/6749/5441/7469/9150/5437/6827/8178 27 Human_herpesvirus_8_type_P R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 27/5323 34/10654 3.9699801988307535e-4 7.956926125006938e-4 2.934773186420096e-4 5431/5435/5433/5439/11198/904/51497/5438/1025/7936/6829/25920/2963/5434/5436/2962/5432/6917/5440/5430/6749/5441/7469/9150/5437/6827/8178 27 Human_herpesvirus_8_type_P R-HSA-5654687 Downstream signaling of activated FGFR1 25/5323 31/10654 4.254488387390267e-4 8.51502867860328e-4 3.140619562751219e-4 5295/4893/2250/5335/2885/3845/3265/5290/8074/2260/2249/2248/2247/2246/2251/5781/6464/6654/2549/10817/2254/26281/10818/2255/27006 25 Human_herpesvirus_8_type_P R-HSA-204005 COPII-mediated vesicle transport 48/5323 68/10654 4.3086128105270465e-4 8.611105432402776e-4 3.176055794841259e-4 6811/23256/374/2153/10484/5861/9570/90411/3998/9632/10652/58485/9117/2801/22872/81562/8615/55014/83696/6399/6396/1453/10959/2890/10802/2157/9554/966/11196/10282/8775/81876/51693/23243/5537/9871/1075/9919/10113/55291/26984/63908/22870/5265/8774/10972/4905/64689 48 Human_herpesvirus_8_type_P R-HSA-201451 Signaling by BMP 23/5323 28/10654 4.432254149833295e-4 8.833118397755589e-4 3.2579413983417545e-4 7321/91851/4089/650/11167/6497/7323/93/4092/92/94/2658/4091/4090/4093/9765/269/57154/4086/658/64750/659/657 23 Human_herpesvirus_8_type_P R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 23/5323 28/10654 4.432254149833295e-4 8.833118397755589e-4 3.2579413983417545e-4 2788/2770/2782/2787/10681/112/111/2792/2785/2783/2784/2771/2791/150/2786/54331/59345/51764/94235/55970/152/2793/2790 23 Human_herpesvirus_8_type_P R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 32/5323 42/10654 4.520367927615151e-4 8.995979737135102e-4 3.3180099580350925e-4 2788/2782/8826/2787/5567/10681/112/5573/111/2792/2785/2783/2784/2791/5568/5566/2641/2786/5577/54331/5575/59345/51764/94235/114/3790/55970/2778/2793/5576/5906/2790 32 Human_herpesvirus_8_type_P R-HSA-1170546 Prolactin receptor signaling 14/5323 15/10654 4.79919136748307e-4 9.23489515315882e-4 3.406129735164253e-4 8454/6776/9978/3717/5618/8945/2690/5617/6777/5781/1442/2689/6500/2688 14 Human_herpesvirus_8_type_P R-HSA-391903 Eicosanoid ligand-binding receptors 14/5323 15/10654 4.79919136748307e-4 9.23489515315882e-4 3.406129735164253e-4 5734/5737/2840/5732/165140/10800/1241/5731/11251/6915/5733/5729/57105/56413 14 Human_herpesvirus_8_type_P R-HSA-6785631 ERBB2 Regulates Cell Motility 14/5323 15/10654 4.79919136748307e-4 9.23489515315882e-4 3.406129735164253e-4 2064/145957/9542/1839/2065/2069/1729/3084/10718/387/1956/685/1950/2066 14 Human_herpesvirus_8_type_P R-HSA-937039 IRAK1 recruits IKK complex 14/5323 15/10654 4.79919136748307e-4 9.23489515315882e-4 3.406129735164253e-4 3654/7334/3551/7314/8517/6233/57162/7189/7311/1147/246330/7316/7335/57161 14 Human_herpesvirus_8_type_P R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 14/5323 15/10654 4.79919136748307e-4 9.23489515315882e-4 3.406129735164253e-4 3654/51135/7334/7314/54106/6233/51311/3665/7189/7311/51284/4615/7316/7335 14 Human_herpesvirus_8_type_P R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 14/5323 15/10654 4.79919136748307e-4 9.23489515315882e-4 3.406129735164253e-4 3654/7334/3551/7314/8517/6233/57162/7189/7311/1147/246330/7316/7335/57161 14 Human_herpesvirus_8_type_P R-HSA-1059683 Interleukin-6 signaling 11/5323 11/10654 4.81763542460453e-4 9.23489515315882e-4 3.406129735164253e-4 9021/3717/3569/3572/3570/7297/5781/6774/6772/3716/867 11 Human_herpesvirus_8_type_P R-HSA-174414 Processive synthesis on the C-strand of the telomere 11/5323 11/10654 4.81763542460453e-4 9.23489515315882e-4 3.406129735164253e-4 2237/1763/6117/10714/6118/3978/5424/5425/5111/6119/57804 11 Human_herpesvirus_8_type_P R-HSA-193692 Regulated proteolysis of p75NTR 11/5323 11/10654 4.81763542460453e-4 9.23489515315882e-4 3.406129735164253e-4 4790/23385/6868/5970/5664/5663/7189/83464/55851/51107/4804 11 Human_herpesvirus_8_type_P R-HSA-196025 Formation of annular gap junctions 11/5323 11/10654 4.81763542460453e-4 9.23489515315882e-4 3.406129735164253e-4 71/1212/1785/2697/1759/1601/1213/1211/1173/8218/60 11 Human_herpesvirus_8_type_P R-HSA-2025928 Calcineurin activates NFAT 11/5323 11/10654 4.81763542460453e-4 9.23489515315882e-4 3.406129735164253e-4 5530/4773/2280/5478/801/805/4772/4775/5532/5534/808 11 Human_herpesvirus_8_type_P R-HSA-2514853 Condensation of Prometaphase Chromosomes 11/5323 11/10654 4.81763542460453e-4 9.23489515315882e-4 3.406129735164253e-4 1459/1460/1457/64151/10051/983/23397/9133/891/10592/9918 11 Human_herpesvirus_8_type_P R-HSA-3371378 Regulation by c-FLIP 11/5323 11/10654 4.81763542460453e-4 9.23489515315882e-4 3.406129735164253e-4 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355 11 Human_herpesvirus_8_type_P R-HSA-400451 Free fatty acids regulate insulin secretion 11/5323 11/10654 4.81763542460453e-4 9.23489515315882e-4 3.406129735164253e-4 5331/2769/2776/2181/2182/2864/23236/5330/2767/948/9630 11 Human_herpesvirus_8_type_P R-HSA-4755510 SUMOylation of immune response proteins 11/5323 11/10654 4.81763542460453e-4 9.23489515315882e-4 3.406129735164253e-4 4792/6612/51588/8517/5970/4791/10210/7329/9641/7341/10401 11 Human_herpesvirus_8_type_P R-HSA-5218900 CASP8 activity is inhibited 11/5323 11/10654 4.81763542460453e-4 9.23489515315882e-4 3.406129735164253e-4 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355 11 Human_herpesvirus_8_type_P R-HSA-5603041 IRAK4 deficiency (TLR2/4) 11/5323 11/10654 4.81763542460453e-4 9.23489515315882e-4 3.406129735164253e-4 10333/929/51135/7096/695/23643/7099/4615/114609/948/7097 11 Human_herpesvirus_8_type_P R-HSA-5625970 RHO GTPases activate KTN1 11/5323 11/10654 4.81763542460453e-4 9.23489515315882e-4 3.406129735164253e-4 64837/3798/5879/89953/147700/3831/3895/998/387/391/3799 11 Human_herpesvirus_8_type_P R-HSA-5655291 Signaling by FGFR4 in disease 11/5323 11/10654 4.81763542460453e-4 9.23489515315882e-4 3.406129735164253e-4 5295/4893/5335/2264/2885/3845/3265/5290/6654/2549/10818 11 Human_herpesvirus_8_type_P R-HSA-68689 CDC6 association with the ORC:origin complex 11/5323 11/10654 4.81763542460453e-4 9.23489515315882e-4 3.406129735164253e-4 1869/84515/4998/990/5001/23594/4999/5000/1870/23595/1871 11 Human_herpesvirus_8_type_P R-HSA-69416 Dimerization of procaspase-8 11/5323 11/10654 4.81763542460453e-4 9.23489515315882e-4 3.406129735164253e-4 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355 11 Human_herpesvirus_8_type_P R-HSA-8875555 MET activates RAP1 and RAC1 11/5323 11/10654 4.81763542460453e-4 9.23489515315882e-4 3.406129735164253e-4 5908/3082/2885/1399/5879/85440/4233/2889/2549/1398/5906 11 Human_herpesvirus_8_type_P R-HSA-8934903 Receptor Mediated Mitophagy 11/5323 11/10654 4.81763542460453e-4 9.23489515315882e-4 3.406129735164253e-4 1459/9140/1460/9474/1457/84557/139341/192111/6714/8408/81631 11 Human_herpesvirus_8_type_P R-HSA-9013700 NOTCH4 Activation and Transmission of Signal to the Nucleus 11/5323 11/10654 4.81763542460453e-4 9.23489515315882e-4 3.406129735164253e-4 182/23385/7534/102/5664/5663/4855/83464/55851/51107/54567 11 Human_herpesvirus_8_type_P R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 11/5323 11/10654 4.81763542460453e-4 9.23489515315882e-4 3.406129735164253e-4 7314/257397/23118/10454/6233/7098/7189/7311/6885/7316/148022 11 Human_herpesvirus_8_type_P R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 11/5323 11/10654 4.81763542460453e-4 9.23489515315882e-4 3.406129735164253e-4 627/4893/2885/3845/3265/4909/5781/6654/4915/10817/10818 11 Human_herpesvirus_8_type_P R-HSA-9614399 Regulation of localization of FOXO transcription factors 11/5323 11/10654 4.81763542460453e-4 9.23489515315882e-4 3.406129735164253e-4 2308/10971/2810/7534/10000/7532/4303/208/7529/2309/207 11 Human_herpesvirus_8_type_P R-HSA-156590 Glutathione conjugation 28/5323 36/10654 5.766405088249584e-4 0.0011038546883220632 4.07137516434951e-4 2938/2949/4259/27306/2944/4258/55748/4257/2940/2687/2686/221357/373156/2729/2730/2954/9446/2946/2939/10327/653689/2948/2947/2678/2937/119391/2941/2950 28 Human_herpesvirus_8_type_P R-HSA-2871809 FCERI mediated Ca+2 mobilization 26/5323 33/10654 6.38985972821594e-4 0.001219882311750316 4.4993227822758816e-4 5335/5530/2885/4773/5336/7410/7409/3702/801/805/6464/2205/4772/3937/4775/10451/2206/6850/4067/695/6654/5532/10768/5534/808/2207 26 Human_herpesvirus_8_type_P R-HSA-418990 Adherens junctions interactions 26/5323 33/10654 6.38985972821594e-4 0.001219882311750316 4.4993227822758816e-4 283/71/5817/1006/1500/999/3728/1008/1012/64403/1016/1010/23705/1003/1007/1002/1000/1009/60/1015/1495/1499/1004/1005/1001/1013 26 Human_herpesvirus_8_type_P R-HSA-210993 Tie2 Signaling 16/5323 18/10654 6.435178419236825e-4 0.0012202555304401904 4.5006993342087606e-4 5295/4893/5291/2885/3845/3265/5290/5781/6464/7010/51378/2886/6654/285/5296/284 16 Human_herpesvirus_8_type_P R-HSA-5654221 Phospholipase C-mediated cascade; FGFR2 16/5323 18/10654 6.435178419236825e-4 0.0012202555304401904 4.5006993342087606e-4 2250/5335/2252/8823/8074/2249/2248/2247/2246/2251/2263/8817/2254/26281/2255/27006 16 Human_herpesvirus_8_type_P R-HSA-5654704 SHC-mediated cascade:FGFR3 16/5323 18/10654 6.435178419236825e-4 0.0012202555304401904 4.5006993342087606e-4 4893/2250/2885/3845/3265/8823/8074/2249/2247/2246/6464/6654/8817/2254/26281/2261 16 Human_herpesvirus_8_type_P R-HSA-5654710 PI-3K cascade:FGFR3 16/5323 18/10654 6.435178419236825e-4 0.0012202555304401904 4.5006993342087606e-4 5295/2250/2885/5290/8823/8074/2249/2247/2246/5781/2549/8817/2254/26281/10818/2261 16 Human_herpesvirus_8_type_P R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 16/5323 18/10654 6.435178419236825e-4 0.0012202555304401904 4.5006993342087606e-4 929/7187/7314/29110/3661/6233/10010/5781/3665/7311/9641/23643/7099/7316/353376/148022 16 Human_herpesvirus_8_type_P R-HSA-2424491 DAP12 signaling 24/5323 30/10654 6.951324142297105e-4 0.0013145850898134445 4.8486174337188364e-4 5295/4893/5335/5291/3824/54209/567/2534/2885/3133/3845/3265/5879/5290/5336/7410/3932/6464/3937/10451/6850/695/6654/5296 24 Human_herpesvirus_8_type_P R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 24/5323 30/10654 6.951324142297105e-4 0.0013145850898134445 4.8486174337188364e-4 11065/7321/8239/55236/3093/7347/7328/7332/7314/10477/29089/7324/6233/7874/7317/8078/7311/997/7319/7320/7316/7322/55284/27338 24 Human_herpesvirus_8_type_P R-HSA-70326 Glucose metabolism 61/5323 91/10654 7.062585098790966e-4 0.001333833185771663 4.91961067284203e-4 23165/7167/2806/348995/57122/3099/6576/23511/23279/5106/23225/9972/5518/4191/8021/2026/55746/5515/2597/5567/10762/5528/79902/5519/9883/226/2821/8604/5208/6396/129401/230/5105/4928/5903/55706/7175/5568/4927/5566/2023/4190/669/8086/5207/5516/9631/5091/5315/79023/23636/5214/53371/5230/10165/3098/9688/5210/5209/5213/8480 61 Human_herpesvirus_8_type_P R-HSA-5218921 VEGFR2 mediated cell proliferation 18/5323 21/10654 7.288863831970469e-4 0.0013710469801580815 5.056867251845542e-4 4893/5335/5579/5578/3845/3265/8877/5921/6714/5580/3791/801/805/5170/5590/7422/10768/808 18 Human_herpesvirus_8_type_P R-HSA-5654688 SHC-mediated cascade:FGFR1 18/5323 21/10654 7.288863831970469e-4 0.0013710469801580815 5.056867251845542e-4 4893/2250/2885/3845/3265/8074/2260/2249/2248/2247/2246/2251/6464/6654/2254/26281/2255/27006 18 Human_herpesvirus_8_type_P R-HSA-5654689 PI-3K cascade:FGFR1 18/5323 21/10654 7.288863831970469e-4 0.0013710469801580815 5.056867251845542e-4 5295/2250/2885/5290/8074/2260/2249/2248/2247/2246/2251/5781/2549/2254/26281/10818/2255/27006 18 Human_herpesvirus_8_type_P R-HSA-3000170 Syndecan interactions 22/5323 27/10654 7.371940988499772e-4 0.0013848225595219199 5.107676069609147e-4 6385/5578/1289/7448/3688/3693/3690/87/6382/7040/2247/2335/3685/9672/3691/8573/1277/3371/6383/1281/7057/1278 22 Human_herpesvirus_8_type_P R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 29/5323 38/10654 8.011527177751145e-4 0.0015029624985461146 5.543414594570266e-4 51741/2064/5308/4609/1387/7913/7022/83741/163732/3815/348/2099/3329/7020/4869/4839/339488/10370/7329/29028/1956/7528/4605/4435/7021/7422/1026/7341/2033 29 Human_herpesvirus_8_type_P R-HSA-170670 Adenylate cyclase inhibitory pathway 13/5323 14/10654 9.015387821999442e-4 0.0016800861808679755 6.196704351684525e-4 2770/107/2773/112/111/2771/196883/115/113/109/114/108/346562 13 Human_herpesvirus_8_type_P R-HSA-177504 Retrograde neurotrophin signalling 13/5323 14/10654 9.015387821999442e-4 0.0016800861808679755 6.196704351684525e-4 1785/6456/163/1759/161/4914/1213/1211/1175/1173/160/26052/4803 13 Human_herpesvirus_8_type_P R-HSA-3371568 Attenuation phase 13/5323 14/10654 9.015387821999442e-4 0.0016800861808679755 6.196704351684525e-4 3305/1387/3306/3312/3303/3337/3297/3326/3304/10728/3320/2033/2288 13 Human_herpesvirus_8_type_P R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 13/5323 14/10654 9.015387821999442e-4 0.0016800861808679755 6.196704351684525e-4 79370/7159/23368/332/64065/7157/604/5875/8626/7161/10397/9540/5876 13 Human_herpesvirus_8_type_P R-HSA-918233 TRAF3-dependent IRF activation pathway 13/5323 14/10654 9.015387821999442e-4 0.0016800861808679755 6.196704351684525e-4 1387/64135/7187/29110/23586/3661/84282/3665/7706/9641/3456/57506/2033 13 Human_herpesvirus_8_type_P R-HSA-110056 MAPK3 (ERK1) activation 10/5323 10/10654 9.651592595424552e-4 0.0017636091924366681 6.504764387620375e-4 3717/3569/3572/983/3570/7297/5781/3716/5595/5604 10 Human_herpesvirus_8_type_P R-HSA-1250342 PI3K events in ERBB4 signaling 10/5323 10/10654 9.651592595424552e-4 0.0017636091924366681 6.504764387620375e-4 5295/145957/9542/1839/5290/2069/3084/10718/685/2066 10 Human_herpesvirus_8_type_P R-HSA-174437 Removal of the Flap Intermediate from the C-strand 10/5323 10/10654 9.651592595424552e-4 0.0017636091924366681 6.504764387620375e-4 2237/1763/6117/10714/6118/5424/5425/5111/6119/57804 10 Human_herpesvirus_8_type_P R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 10/5323 10/10654 9.651592595424552e-4 0.0017636091924366681 6.504764387620375e-4 5563/53632/1432/51422/5600/6300/5571/5564/5565/10891 10 Human_herpesvirus_8_type_P R-HSA-2465910 MASTL Facilitates Mitotic Progression 10/5323 10/10654 9.651592595424552e-4 0.0017636091924366681 6.504764387620375e-4 5518/55844/84930/5515/983/5519/2029/891/5516/10776 10 Human_herpesvirus_8_type_P R-HSA-381183 ATF6 (ATF6-alpha) activates chaperone genes 10/5323 10/10654 9.651592595424552e-4 0.0017636091924366681 6.504764387620375e-4 811/3309/4801/468/7184/7494/4800/22926/4802/1649 10 Human_herpesvirus_8_type_P R-HSA-390450 Folding of actin by CCT/TriC 10/5323 10/10654 9.651592595424552e-4 0.0017636091924366681 6.504764387620375e-4 10576/10574/10693/10575/60/22948/10694/7203/908/6950 10 Human_herpesvirus_8_type_P R-HSA-399997 Acetylcholine regulates insulin secretion 10/5323 10/10654 9.651592595424552e-4 0.0017636091924366681 6.504764387620375e-4 5331/5578/2769/2776/1131/23236/4082/5330/2767/9630 10 Human_herpesvirus_8_type_P R-HSA-418889 Caspase activation via Dependence Receptors in the absence of ligand 10/5323 10/10654 9.651592595424552e-4 0.0017636091924366681 6.504764387620375e-4 90249/836/26060/219699/1612/1613/842/9500/23604/1630 10 Human_herpesvirus_8_type_P R-HSA-442729 CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde 10/5323 10/10654 9.651592595424552e-4 0.0017636091924366681 6.504764387620375e-4 814/818/801/805/3838/10645/84254/816/1385/808 10 Human_herpesvirus_8_type_P R-HSA-450341 Activation of the AP-1 family of transcription factors 10/5323 10/10654 9.651592595424552e-4 0.0017636091924366681 6.504764387620375e-4 3725/1432/1386/5601/5594/2353/5600/5602/5595/5599 10 Human_herpesvirus_8_type_P R-HSA-5602498 MyD88 deficiency (TLR2/4) 10/5323 10/10654 9.651592595424552e-4 0.0017636091924366681 6.504764387620375e-4 10333/929/7096/695/23643/7099/4615/114609/948/7097 10 Human_herpesvirus_8_type_P R-HSA-8853334 Signaling by FGFR3 fusions in cancer 10/5323 10/10654 9.651592595424552e-4 0.0017636091924366681 6.504764387620375e-4 5295/4893/2885/3845/3265/5290/6654/2549/10818/2261 10 Human_herpesvirus_8_type_P R-HSA-937042 IRAK2 mediated activation of TAK1 complex 10/5323 10/10654 9.651592595424552e-4 0.0017636091924366681 6.504764387620375e-4 7314/257397/23118/10454/6233/3656/7189/7311/6885/7316 10 Human_herpesvirus_8_type_P R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 10/5323 10/10654 9.651592595424552e-4 0.0017636091924366681 6.504764387620375e-4 2308/7295/1387/10628/23411/8850/4303/23410/2309/2033 10 Human_herpesvirus_8_type_P R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 25/5323 32/10654 0.0010211999887004236 0.0018635906408579713 6.873528492447387e-4 51807/10381/10576/7846/113457/81027/10574/10693/79861/10575/10376/5202/84617/10382/7277/347733/10383/60/84790/22948/7280/10694/7203/908/6950 25 Human_herpesvirus_8_type_P R-HSA-201681 TCF dependent signaling in response to WNT 140/5323 233/10654 0.0010796934761420085 0.0019677833172691787 7.257824975975051e-4 56998/27123/9070/5689/857/7478/5682/1459/5526/1452/5929/1460/143471/5705/6657/8452/55366/5709/9978/5695/1457/4609/5711/1387/5683/324/5699/8312/5702/1855/6932/90780/5518/25776/6659/80351/5696/5691/7314/5515/5718/51176/8945/2535/6662/5700/122706/5707/1856/7473/1454/8322/23198/7471/7534/5528/7091/89780/83439/8323/9861/81847/5519/2932/8321/5698/5692/5713/5710/8313/5719/6233/7474/1857/7514/4040/7479/7855/7089/331/8607/4221/123169/7090/6597/864/10023/4041/79577/6736/5706/23401/8658/5714/6934/10524/5688/5687/5708/5529/7088/208/57680/5704/7311/5694/55553/5516/5684/8295/5720/7015/1487/1499/5525/139285/207/8085/5690/5717/9491/10197/64750/7316/10213/5715/5701/1455/5685/5686/2033/54894/3065/5527/5716/23072/9736/5693/5721/6259 140 Human_herpesvirus_8_type_P R-HSA-180292 GAB1 signalosome 15/5323 17/10654 0.0011546164803066877 0.0020854241178324896 7.691722515927263e-4 5295/374/55824/2885/5829/1839/5290/2069/6714/1445/5781/1956/2549/685/1950 15 Human_herpesvirus_8_type_P R-HSA-2033519 Activated point mutants of FGFR2 15/5323 17/10654 0.0011546164803066877 0.0020854241178324896 7.691722515927263e-4 2250/2252/8823/8074/2249/2248/2247/2246/2251/2263/8817/2254/26281/2255/27006 15 Human_herpesvirus_8_type_P R-HSA-4655427 SUMOylation of DNA methylation proteins 15/5323 17/10654 0.0011546164803066877 0.0020854241178324896 7.691722515927263e-4 1912/6045/80012/1911/1789/57332/1788/84733/7703/6015/8535/1786/7329/648/7341 15 Human_herpesvirus_8_type_P R-HSA-5655862 Translesion synthesis by POLK 15/5323 17/10654 0.0011546164803066877 0.0020854241178324896 7.691722515927263e-4 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/51426/7311/5983/7316/5981 15 Human_herpesvirus_8_type_P R-HSA-5656121 Translesion synthesis by POLI 15/5323 17/10654 0.0011546164803066877 0.0020854241178324896 7.691722515927263e-4 5982/6117/7314/6118/11201/51455/5985/5984/6233/5111/6119/7311/5983/7316/5981 15 Human_herpesvirus_8_type_P R-HSA-9034015 Signaling by NTRK3 (TRKC) 15/5323 17/10654 0.0011546164803066877 0.0020854241178324896 7.691722515927263e-4 5295/4893/5335/2885/3845/3265/5290/3667/6714/25920/4908/6464/6654/4916/581 15 Human_herpesvirus_8_type_P R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 15/5323 17/10654 0.0011546164803066877 0.0020854241178324896 7.691722515927263e-4 929/7314/257397/23118/10454/6233/3656/7189/7311/23643/6885/7099/7316/353376/148022 15 Human_herpesvirus_8_type_P R-HSA-167044 Signalling to RAS 17/5323 20/10654 0.0012634537041331141 0.002276157953540706 8.395210945988615e-4 4893/5898/1432/5603/2885/3845/3265/9261/6714/4914/5600/6300/6464/6654/25759/53358/4803 17 Human_herpesvirus_8_type_P R-HSA-8876384 Listeria monocytogenes entry into host cells 17/5323 20/10654 0.0012634537041331141 0.002276157953540706 8.395210945988615e-4 6456/30011/2885/7314/2060/1500/6714/999/9146/6455/6233/4233/7311/1499/7316/867/10254 17 Human_herpesvirus_8_type_P R-HSA-977606 Regulation of Complement cascade 34/5323 47/10654 0.0014872251257607263 0.0026758641329224318 9.86945735630688e-4 5199/7448/717/975/732/720/714/727/629/722/27202/731/712/3075/716/1191/721/725/728/4179/2147/930/1378/1361/966/715/3426/1991/1604/710/719/713/5627/718 34 Human_herpesvirus_8_type_P R-HSA-6806834 Signaling by MET 53/5323 79/10654 0.0015036732354153507 0.0027020028636390784 9.96586549787952e-4 5295/4893/5770/10653/5908/3082/1280/1289/3688/3910/6456/30011/2885/3845/3265/1399/7314/5879/3918/5290/3911/2060/6714/9146/6455/2335/6233/5781/6464/85440/5747/382/1277/3912/6774/4233/5795/2889/5771/3913/6654/5867/7311/2549/10048/7316/3915/1281/867/1398/5906/1278/10254 53 Human_herpesvirus_8_type_P R-HSA-383280 Nuclear Receptor transcription pathway 37/5323 52/10654 0.0015296569085549324 0.002745187844817334 0.0010125145756143686 7068/5915/6097/7181/5469/9612/8856/29959/7067/5914/8431/7421/10062/2516/5465/2099/7101/2494/5467/2103/6257/5241/7182/3172/2063/9970/2908/367/5468/2100/4306/9611/3164/6256/7376/6258/5916 37 Human_herpesvirus_8_type_P R-HSA-6807505 RNA polymerase II transcribes snRNA genes 50/5323 74/10654 0.0015985675144773424 0.00286520317563009 0.0010567801336068788 6884/51585/5431/5435/5433/2960/5439/904/55197/2959/5438/6667/1025/7702/6829/2957/2963/5434/5436/6878/2962/51808/8812/129685/905/5452/64859/6880/6908/80237/6882/2961/5432/22916/6877/5440/57508/5430/5451/5441/84524/4686/2958/5437/6827/80789/51593/79035/1022/8178 50 Human_herpesvirus_8_type_P R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 29/5323 39/10654 0.001636055486101657 0.002924942908443496 0.001078814090347244 9134/10576/10574/6468/54461/10693/8877/10575/898/26985/26190/10238/7157/26224/2629/8237/6774/26272/26270/55135/22948/10694/8841/22803/7203/908/6950/3801/55294 29 Human_herpesvirus_8_type_P R-HSA-76009 Platelet Aggregation (Plug Formation) 29/5323 39/10654 0.001636055486101657 0.002924942908443496 0.001078814090347244 5770/5908/2244/3690/2885/9564/7094/6714/2335/1445/2266/2243/2147/5170/6464/5747/3674/1277/150/6850/6654/7450/151/207/54518/152/1398/5906/1278 29 Human_herpesvirus_8_type_P R-HSA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 12/5323 13/10654 0.0016858735773538102 0.0029949799537080947 0.0011046460308817498 5925/5422/1869/28227/5518/5558/5515/7027/5557/5519/23649/5516 12 Human_herpesvirus_8_type_P R-HSA-1502540 Signaling by Activin 12/5323 13/10654 0.0016858735773538102 0.0029949799537080947 0.0011046460308817498 10272/130399/4089/4088/10589/91/93/92/3625/8928/3624/4087 12 Human_herpesvirus_8_type_P R-HSA-2995383 Initiation of Nuclear Envelope Reformation 12/5323 13/10654 0.0016858735773538102 0.0029949799537080947 0.0011046460308817498 5520/4001/5518/5515/7444/2010/7112/4000/7443/23141/8815/23592 12 Human_herpesvirus_8_type_P R-HSA-2995410 Nuclear Envelope Reassembly 12/5323 13/10654 0.0016858735773538102 0.0029949799537080947 0.0011046460308817498 5520/4001/5518/5515/7444/2010/7112/4000/7443/23141/8815/23592 12 Human_herpesvirus_8_type_P R-HSA-5140745 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 12/5323 13/10654 0.0016858735773538102 0.0029949799537080947 0.0011046460308817498 1212/163/4920/2535/161/7474/1213/1211/7855/1175/1173/160 12 Human_herpesvirus_8_type_P R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 22/5323 28/10654 0.0018150792730276828 0.0032204496054854346 0.0011878065727784532 10381/10576/7846/113457/81027/10574/10693/10575/5202/84617/10382/7277/347733/10383/60/84790/22948/7280/10694/7203/908/6950 22 Human_herpesvirus_8_type_P R-HSA-110312 Translesion synthesis by REV1 14/5323 16/10654 0.002058169195974873 0.003633430437561664 0.001340127337536304 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/7311/5983/7316/5981 14 Human_herpesvirus_8_type_P R-HSA-1433559 Regulation of KIT signaling 14/5323 16/10654 0.002058169195974873 0.003633430437561664 0.001340127337536304 5777/5578/2534/2885/3815/9306/6714/7525/3932/8651/4067/6654/867/4254 14 Human_herpesvirus_8_type_P R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 14/5323 16/10654 0.002058169195974873 0.003633430437561664 0.001340127337536304 22938/1387/9794/2648/55534/3280/84441/8850/10046/3175/4851/2033/3516/6928 14 Human_herpesvirus_8_type_P R-HSA-418038 Nucleotide-like (purinergic) receptors 14/5323 16/10654 0.002058169195974873 0.003633430437561664 0.001340127337536304 10161/64805/2840/5028/5029/53829/27334/134/9934/5032/140/5031/5030/2846 14 Human_herpesvirus_8_type_P R-HSA-202433 Generation of second messenger molecules 25/5323 33/10654 0.0022156187883217823 0.0039064857583568265 0.0014408390220850005 5335/3115/3113/3117/3127/5062/3126/916/3702/3932/3120/3937/3123/3122/920/5063/3125/5058/55740/3119/919/915/917/7408/7454 25 Human_herpesvirus_8_type_P R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 23/5323 30/10654 0.0025485782186586365 0.004487921844371341 0.0016552915641903799 4893/817/6196/6197/3845/3265/5923/818/57554/5594/6195/801/805/5170/2904/27330/816/5595/815/1742/88/1385/808 23 Human_herpesvirus_8_type_P R-HSA-186797 Signaling by PDGF 40/5323 58/10654 0.0025705888357266584 0.004521023114834261 0.001667500389491109 5295/4893/5335/5291/1280/1289/6696/6776/5327/2885/8440/9564/3845/3265/1399/5290/5340/1284/5921/6778/6714/1292/6777/5781/1291/5782/6774/6772/2889/5159/7058/2886/6654/1282/1281/1398/5155/5296/7057/5156 40 Human_herpesvirus_8_type_P R-HSA-202733 Cell surface interactions at the vascular wall 85/5323 137/10654 0.002790420098515627 0.00490152444271097 0.0018078416565716596 5295/5777/4893/857/5335/6385/960/5291/7056/5175/962/9463/3688/972/51744/2534/3690/2885/51206/4072/6382/7040/3845/4282/3265/3635/5290/6401/4680/4312/50848/6714/8797/2335/83692/2734/5478/7525/3685/3932/634/9672/5781/2147/6464/483/3684/7010/8832/10461/3678/1277/338/51378/4067/140885/5624/2886/6654/285/3897/8795/5669/3676/2817/8793/6383/5196/2621/83953/54210/682/1088/23759/5678/6520/5296/3687/1278/3689/961/2207/5627/6566/284 85 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-983169 Class I MHC mediated antigen processing & presentation 350/4699 371/10654 2.0418593069742723e-99 2.8667704669918786e-96 1.1649344677684797e-96 8454/8773/5689/127544/11065/221687/9666/84937/55070/5682/55819/93611/8916/3107/7321/51665/65264/122769/9021/10484/8697/26235/9817/9039/154881/7174/6478/811/143471/5705/57674/10333/9690/8452/5709/9978/5695/23304/567/55236/54620/4734/7337/84676/7704/3106/3093/10489/5711/23327/51465/51752/10616/5683/929/3309/89910/25898/5699/7328/9632/7428/5702/22954/401036/83737/51529/140461/10075/29945/79176/8924/90135/56658/51434/6468/10425/25793/23295/3133/51666/90293/54461/29882/7334/92591/55182/84961/4591/3551/7332/5696/5691/9820/55658/7314/996/10324/283807/9354/5718/197131/8945/51088/64410/10952/146330/51320/5700/122706/5707/10477/148581/92912/23198/10533/140462/6892/51130/8517/6477/7323/10517/9604/1515/22872/64718/4008/7096/84861/11059/84085/27252/51444/26118/51433/9861/26249/55905/10134/143279/6502/5698/27246/5692/5713/9903/201456/26190/79654/5710/9040/7324/5719/64682/8925/51191/6233/3685/26091/6047/51128/131405/868/136371/6396/127247/1535/5930/11275/29116/26268/115290/51725/140459/23608/55585/64320/51132/1514/899/3135/23352/26224/10293/114088/285231/653361/142678/246184/142686/151636/11146/255488/9616/91694/10802/10193/6890/140739/821/150726/390594/81559/2209/144699/5706/200845/79876/26263/8881/7326/6049/57630/89890/22888/29927/7317/80196/140456/55958/84078/50489/5714/26272/8651/64219/140458/5688/55336/5687/26270/63893/89122/118424/5708/55008/2923/10422/84727/695/90933/63891/9246/10393/5704/9870/4012/25847/7327/51343/7311/9871/7318/55175/9320/26232/57520/5694/8673/92369/3105/997/84261/7325/140691/23643/57154/1147/140460/5684/79754/6737/8065/5720/57531/84708/7319/54850/79791/26046/991/84231/10273/7320/5690/223082/5717/25897/9491/6500/26259/10197/7099/53339/154214/7336/4615/64750/51619/23376/6891/54778/142689/7316/10213/114907/54926/7335/222235/25831/7322/5715/9867/5701/9341/23291/5685/5686/114609/55521/55294/135892/8453/80176/8139/126433/26267/142685/1520/5716/90025/7064/84541/23194/55284/3134/80204/26234/27338/7097/23014/90678/5693/5721/51676/10427/57542/642/4360 350 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 300/4699 309/10654 4.0052536267701356e-95 2.8116880459926353e-92 1.1425512977417966e-92 8454/5689/127544/11065/221687/9666/84937/55070/5682/55819/93611/8916/7321/51665/65264/122769/9021/8697/26235/9817/9039/154881/7174/6478/143471/5705/57674/9690/8452/5709/9978/5695/23304/55236/54620/4734/7337/84676/7704/3093/10489/5711/23327/51465/10616/5683/89910/25898/5699/7328/7428/5702/22954/401036/83737/51529/140461/10075/29945/79176/8924/90135/56658/51434/6468/10425/25793/23295/51666/90293/54461/29882/7334/92591/55182/84961/4591/7332/5696/5691/9820/55658/7314/996/10324/283807/9354/5718/197131/8945/51088/64410/146330/51320/5700/122706/5707/10477/148581/92912/23198/10533/140462/51130/6477/7323/10517/9604/64718/4008/84861/11059/84085/27252/51444/26118/51433/9861/26249/55905/143279/6502/5698/27246/5692/5713/9903/201456/26190/79654/5710/9040/7324/5719/64682/8925/51191/6233/26091/6047/131405/868/136371/127247/5930/11275/29116/26268/115290/51725/140459/23608/55585/64320/51132/899/23352/26224/10293/114088/285231/142678/246184/142686/151636/11146/255488/9616/91694/10193/140739/150726/390594/81559/144699/5706/200845/79876/26263/8881/7326/6049/57630/89890/22888/7317/80196/140456/55958/84078/5714/26272/8651/64219/140458/5688/55336/5687/26270/63893/89122/118424/5708/55008/10422/84727/90933/63891/9246/10393/5704/9870/4012/25847/7327/51343/7311/7318/55175/9320/26232/57520/5694/92369/997/84261/7325/140691/57154/140460/5684/79754/6737/8065/5720/57531/84708/7319/54850/79791/26046/991/84231/10273/7320/5690/223082/5717/25897/9491/6500/26259/10197/53339/154214/7336/64750/51619/23376/54778/142689/7316/10213/114907/54926/7335/222235/25831/7322/5715/9867/5701/23291/5685/5686/55521/55294/135892/8453/80176/8139/126433/26267/142685/5716/90025/7064/84541/23194/55284/80204/26234/27338/23014/90678/5693/5721/51676/57542/642 300 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-3700989 Transcriptional Regulation by TP53 324/4699 365/10654 5.548731936317116e-74 2.5968065461964105e-71 1.0552325296434657e-71 6884/6875/834/5563/3725/9134/4436/83990/64769/9156/57060/1763/7531/1459/79370/7486/6874/10971/9997/133383/9212/5982/27327/7295/7533/2810/55367/1460/11200/472/53632/79813/5431/7001/639/5435/5433/1869/28996/84289/1457/6790/6341/25904/29117/4194/1647/5928/1432/1387/4683/56950/51499/2965/84126/5439/192669/1107/8900/6873/5371/2475/672/55571/6881/2967/51616/5518/1386/55835/4513/4343/6117/11198/7159/57472/904/144455/85456/29883/51497/51230/637/83695/7296/7314/5515/1263/27166/23368/9377/23774/6118/2176/1329/3622/7027/6446/2936/7832/51422/7249/404672/898/117584/27244/7534/332/5438/5934/64065/116028/890/10769/983/1643/8797/9656/5519/27154/5458/83860/57459/2177/10000/5985/2877/900/7994/2068/54541/3066/7157/5984/1337/6233/1025/2353/604/63970/839/10419/5325/50484/5600/6883/7936/6829/79733/26523/7874/317/5608/5884/5810/57521/26155/26013/5875/253260/28956/25920/5170/80010/2963/5434/83667/1820/7862/1029/5457/9219/8445/7532/5436/1345/55240/204851/6878/4869/5931/4850/4292/580/11073/891/84987/80196/54971/4331/5366/641/5111/1108/8148/2966/246175/64223/2962/84883/6119/147923/3364/5571/10524/54457/4848/8812/144715/23019/1616/843/6794/54815/94241/1874/10128/25824/905/1111/2071/55215/8626/208/79109/55004/7311/7161/5562/6880/6908/5983/4697/5564/6882/5565/1020/53615/10397/8795/5432/665/7248/6877/7529/5516/1017/27161/27113/9891/6917/5440/27165/5305/8621/902/5883/25946/9540/5430/10111/8793/207/22974/57690/4849/1027/58484/3486/355/6749/545/5441/8794/192670/8550/7469/9337/7316/6872/2539/1026/54205/5933/124446/5395/6879/9150/112858/5876/143686/10848/5437/1350/9099/8649/28984/51755/2033/995/5728/3065/91875/6827/23112/10498/10542/5527/2968/1349/5932/8851/5300/7156/581/1327/3276/5052/138474/133746/1022/8178/10919/4193 324 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8951664 Neddylation 228/4699 234/10654 2.8455278159232975e-73 9.987802633890774e-71 4.058621253237967e-71 8454/5689/56995/5682/64344/80344/80067/93611/55884/7321/51665/122769/9021/4738/26235/9817/9039/154881/5929/3091/143471/5705/140825/8452/5709/9978/5695/54620/7704/10980/10489/5711/7347/5683/23113/5699/79269/10987/7428/5702/401036/140461/79176/90135/6468/26094/25793/1154/51666/90293/54461/92591/84961/5696/5691/9820/7314/51514/10324/283807/5718/51397/54165/8945/51088/64410/23363/23038/146330/5700/122706/5707/23198/140462/55827/51130/28991/332/7323/9306/10517/50717/4008/84861/84085/79016/27252/1643/26118/9861/122416/26249/6502/90864/55832/5698/5692/10920/5713/9903/201456/26190/10238/5710/9040/5719/10116/6233/83987/136371/8835/127247/11275/54939/26268/115290/54951/51725/140459/55208/10537/8451/899/26224/23412/9655/149951/285231/142686/9616/140739/5931/150726/390594/144699/5706/200845/26263/8450/89890/140456/55958/84078/5714/55527/26272/140458/5688/55336/5687/26270/1161/5708/1642/84727/5704/2873/7311/2034/55175/8533/26232/51667/5694/51122/92369/84261/150684/51138/56929/9318/140460/5684/79754/8065/5720/29099/11091/25879/54850/79791/5690/5717/9491/6500/28952/26259/10197/53339/142689/7316/10213/114907/64708/222235/54876/7322/5715/5701/23291/170622/5685/5686/55294/8453/123879/80176/8139/23142/126433/26043/123228/26267/142685/5716/84541/23194/80204/26234/8883/23014/8816/5693/5721/84259/51676/50813/57542 228 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5663205 Infectious disease 331/4699 383/10654 6.892265695446565e-69 1.9353482072813953e-66 7.864437909330608e-67 3839/6804/6158/6884/23165/6875/5689/6138/2237/6227/7852/6206/6234/6191/162/6128/5682/6132/6129/27243/6874/6176/1174/811/6224/6146/348995/6154/143471/6202/57122/5705/3981/6169/5431/23511/5435/5709/9978/6175/5433/6218/5695/2960/292/567/51271/23279/5605/5711/23327/112755/29082/23225/5683/2965/6192/2534/6156/5699/6143/5439/5702/6456/6873/3836/6139/30011/2885/163/9972/6881/2967/51616/3921/8021/7040/11198/904/55690/51497/5062/55746/6208/5696/6170/5691/92421/7296/7314/5879/5718/137492/3303/8945/6203/51606/161/5606/6147/25978/5700/51160/122706/5707/2959/8027/10053/6222/2060/8106/23198/404672/9636/10015/91782/5438/6134/3978/10762/79720/6155/1500/51534/4836/926/9397/6714/6231/9861/79902/6142/11168/9883/23521/83860/999/5698/9146/6455/5692/5713/5710/2068/5902/6207/5478/5719/6233/6844/7514/1025/3932/1213/5610/1211/6188/6396/129401/6883/7936/1175/6829/801/5608/8907/200916/6122/2957/940/25920/6230/60489/1173/4928/2963/3838/5434/5903/6857/6194/55706/7175/1938/5436/6136/6878/6125/4869/821/5706/6232/160/6160/293/5611/920/4233/4331/5714/6193/4927/6210/6229/8148/6205/2966/2962/10898/3840/5688/54457/8812/5687/5708/128866/140801/905/6181/2071/5901/8086/5704/3326/7311/6223/25873/93343/6880/6908/7251/8905/5694/3304/1104/2547/9045/6882/2961/6187/6416/5432/6168/22916/1234/6157/6137/6877/5905/6144/3837/6917/81929/5440/164/5684/9349/8065/4736/5720/902/51121/9631/5604/1499/3159/6217/3843/5430/6152/5690/7520/5717/9491/6500/127833/6749/51065/6141/79023/5441/23636/10197/7469/919/130340/4686/7316/10213/6872/53371/3055/6209/9688/11224/6165/8731/6130/6879/9150/5715/6204/5701/2958/867/6228/5437/5685/3320/8815/5686/6124/6827/5609/2968/5716/6189/6135/6201/375/6161/138474/1022/5693/10254/5721/6457/8178/8480/6133/291 331 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-449147 Signaling by Interleukins 371/4699 461/10654 3.527305730296846e-60 8.25389540889462e-58 3.354034571615598e-58 5295/729230/8454/6804/3605/7124/2308/834/1052/5689/3725/7291/5777/5897/9252/1437/4790/5682/5291/1511/26469/5657/759/5783/1848/356/3593/9021/8878/5908/3082/5743/3091/941/143471/10538/3383/5705/11009/6097/6349/6657/3576/3313/3662/6776/4985/5709/9978/6175/2920/5695/84868/1435/4792/7133/3606/177/4609/3603/5711/4988/1432/3558/3717/4088/836/5683/2534/84867/5699/3181/5702/4001/3654/3563/2885/85480/51135/8660/6196/3594/1154/9846/6347/5518/1386/6382/9235/7040/3588/6197/4282/7334/3600/3312/1399/3551/3569/5062/5696/5691/51231/4692/7314/3572/3596/5515/257397/3598/5718/54014/8945/1326/5601/1072/3635/3592/5290/3667/6627/6283/5606/90865/64109/9049/3587/7412/5700/122706/5707/27250/8767/1849/29110/1439/5594/4582/23198/23118/6367/4312/9987/8517/6778/7534/332/5528/4313/3565/3976/50615/3185/5970/5443/84818/9261/3718/3627/8809/9861/149233/5519/5598/4208/3567/598/2247/5698/5692/5713/2335/595/6195/5710/3458/10454/7157/5478/5719/6233/7525/6844/7409/2353/604/3932/7076/302/51561/3570/8835/5600/6777/6773/7850/7297/5781/5608/4791/1846/59067/3557/9655/3562/351/6464/3566/6597/5782/6351/7184/6775/50616/3684/9446/3595/54472/821/4318/5706/3726/301/4478/1438/53833/3581/79155/6774/920/6850/5780/1440/5714/6772/8651/7867/5566/64127/8503/1901/3552/5688/79923/5687/4067/3636/5708/5602/29949/3656/57162/5771/998/6648/116379/7189/163702/112744/6654/5704/7006/3716/7311/2939/6888/5293/2185/6356/5008/5694/23765/246778/6416/1234/3586/3554/829/5595/5516/6095/1147/5778/1845/596/5684/2208/5720/6885/2309/5604/4215/3561/3578/10392/207/5292/5451/7422/5690/3553/2625/1230/5717/2919/9491/6500/3568/25930/246330/10197/4615/3597/2357/1436/7316/10213/3560/6352/4314/7335/1441/4205/3055/1026/6348/4793/3146/6364/5715/7132/5701/867/466/6950/23291/5685/3320/5686/4843/9466/6288/2002/942/6285/5609/1398/58985/5716/1385/53832/6363/3575/6845/5896/5296/6935/3687/5599/7431/375/3559/3574/3162/57161/4170/5693/3689/5721/5724/5034 371 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 224/4699 244/10654 1.6441369594654442e-57 3.297668987270691e-55 1.3400334316244675e-55 8449/23165/6633/8683/6431/84271/55696/4904/51639/51585/9128/199746/23450/348995/57122/5431/9092/23511/81608/5435/6625/5433/51645/3190/1477/9416/65109/56339/22826/23279/22938/988/23020/23225/6631/3181/5439/1660/9410/6638/57721/9877/9972/8021/3312/10907/10291/55746/26121/10262/7919/53981/6432/10084/8563/6430/51340/56001/6627/83443/11051/80145/9129/9879/8106/51690/27238/55749/5438/85313/10762/54883/22794/9785/11338/1655/9343/29107/3185/4116/6626/11157/285755/1478/24144/79902/9883/51213/10236/10250/4670/26097/51362/10465/55660/23283/2521/1977/3191/10285/6636/23524/10914/57187/6396/129401/79228/8175/2733/84950/3188/84324/56259/5725/1994/10450/7536/4928/2963/6635/5434/5903/220988/6632/10283/55706/7175/24148/7884/23350/5436/10523/6428/27258/10212/6637/55110/5093/84321/6429/57819/4927/10181/2962/10898/10569/23658/6434/9295/84844/10482/51692/10421/11193/8086/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/81929/5440/51691/10946/9631/27339/5430/79869/85437/11325/57703/3184/25804/29894/11017/51503/3178/79023/5441/23636/3183/10594/4686/8189/10713/53371/10978/5546/7307/10772/9688/9984/5437/6629/10189/10949/51729/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/84248/6427/5356/84991/8480/10992/55339/6628 224 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5663202 Diseases of signal transduction 311/4699 377/10654 5.278574241504222e-55 9.26389779383991e-53 3.7644568932832748e-53 5295/8454/2308/27123/5689/374/4893/11052/2250/5335/71/79718/5682/5291/892/5526/817/1452/9530/613/5908/3082/941/55109/143471/23385/2064/5705/54845/5431/6776/5435/5709/9978/5433/5695/8546/9759/9612/22866/5605/4609/4089/22938/5037/3549/5711/1387/3717/10827/4088/2244/6907/5683/324/2534/3690/408/9965/5699/8312/11064/5439/2264/5702/4296/5894/6868/9794/9542/2885/2475/8660/8826/9846/5518/2252/6469/1185/4140/7040/3845/3265/80351/4763/5696/7750/5691/7314/5879/5515/5718/818/8805/26127/5290/3667/8823/79885/2065/2648/9734/55869/55750/5700/3815/122706/5707/8844/51564/7094/8322/55534/5594/3280/84335/8074/7249/23198/84441/7414/10533/10013/23164/2260/5438/5528/83933/3714/89780/57085/2249/6714/2099/50846/9861/2248/5519/9061/8850/399687/2932/7046/2247/5698/10000/5692/5713/2335/1445/5710/3066/5719/6233/2266/7409/2246/4040/2251/3932/2931/2243/7855/6777/369/801/5781/5663/940/57670/253260/5170/2963/5434/7276/6464/142678/572/283455/3674/5436/4303/4041/409/930/5706/6199/10046/84447/673/6774/2263/4233/8658/1024/5714/6772/6934/64223/10014/2962/8503/5688/5159/5687/29851/5708/3084/5529/816/4087/208/6654/5704/10718/79109/56829/7048/7311/5293/7450/1956/11160/60/9444/2549/5694/4851/5432/22916/11140/7529/5595/5516/4000/1147/27044/815/5440/5684/22906/8841/5720/8087/1487/2309/5604/1499/10018/5525/10142/842/139285/5430/23462/207/5690/5717/1027/9491/6500/8817/5441/10197/54518/2100/2254/4686/7316/10213/152831/1950/9611/1026/50852/26281/10818/7415/5715/80853/10256/2261/5701/867/5437/5685/2255/3164/3320/5686/2033/54894/55294/5728/3065/2066/27006/942/5527/1488/5716/1385/5906/5296/3516/9715/5693/5721/5245/5156/4193 311 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-913531 Interferon Signaling 186/4699 199/10654 5.2813040857573133e-51 8.238834373781409e-49 3.3479144029011277e-49 80263/3839/3443/23165/201626/5777/5335/960/5770/3107/817/9021/348995/3383/57122/11274/55223/3662/3115/23511/4684/567/4734/6672/3113/23279/3106/3459/3717/23225/3117/1973/11074/3836/5371/4599/684/9972/3133/3429/117854/8021/3127/91543/7334/4938/4261/55746/5696/7314/3445/818/115362/7412/10410/85363/9830/163351/9636/2634/3444/10762/2317/115361/103/3434/10475/3433/79902/23586/9883/3451/10437/3448/1981/10612/3458/3661/7324/1977/3439/51191/6233/5580/81603/10107/5610/10581/3452/4940/6396/3437/129401/6773/7297/5781/3430/3660/3446/8554/3135/3665/3120/4928/3838/5903/10379/55706/7175/3455/2316/2633/4600/3123/23650/2209/8638/25820/1982/7706/23087/9470/3122/3394/3663/6772/8651/4927/3659/3840/25939/2635/3440/5771/3454/816/8086/10346/9246/3716/7311/7318/7726/79097/3456/3105/1974/5595/3460/815/3837/81929/3441/6737/51447/9631/23321/4281/3119/4502/54739/79023/2537/23636/3449/51127/7316/53371/8519/3664/9688/6041/1958/4939/388646/7341/6059/55128/3669/3134/5300/9775/80128/5495/5724/8480 186 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-72163 mRNA Splicing - Major Pathway 174/4699 183/10654 7.454873671070322e-51 1.0466642634182731e-48 4.2532016102317e-49 8449/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/5431/9092/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/22938/988/23020/6631/3181/5439/1660/9410/6638/3312/10907/10291/26121/10262/53981/6432/10084/6430/51340/6627/83443/11051/9129/9879/8106/51690/27238/55749/5438/85313/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/10236/10250/4670/51362/10465/55660/23283/2521/3191/10285/6636/23524/10914/8175/84950/3188/56259/5725/1994/10450/7536/2963/6635/5434/220988/6632/10283/24148/23350/5436/10523/6428/27258/6637/55110/5093/6429/57819/10181/2962/10898/10569/23658/6434/9295/84844/51692/10421/11193/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/51691/10946/27339/5430/79869/11325/57703/3184/25804/29894/11017/51503/3178/5441/3183/10594/4686/8189/10713/10978/5546/7307/10772/5437/6629/10189/10949/51729/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/84991/10992/55339/6628 174 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-162906 HIV Infection 209/4699 233/10654 1.6464190166943533e-49 2.1014293631262474e-47 8.539321598548705e-48 6884/23165/6875/5689/2237/7852/162/5682/27243/6874/1174/348995/143471/57122/5705/3981/5431/23511/5435/5709/9978/5433/5695/2960/292/567/51271/23279/5711/23327/29082/23225/5683/2965/2534/5699/5439/5702/6873/3836/163/9972/6881/2967/51616/8021/11198/904/55690/51497/5062/55746/5696/5691/92421/7314/5879/5718/137492/8945/51606/161/25978/5700/51160/122706/5707/2959/10053/23198/404672/10015/91782/5438/3978/10762/79720/51534/4836/926/9397/9861/79902/11168/9883/83860/5698/5692/5713/5710/2068/5902/5478/5719/6233/7514/1025/3932/6396/129401/6883/7936/1175/6829/8907/2957/940/25920/60489/1173/4928/2963/5434/5903/55706/7175/5436/6878/4869/5706/160/293/920/4331/5714/4927/8148/2966/2962/5688/54457/8812/5687/5708/128866/905/2071/5901/8086/5704/7311/93343/6880/6908/7251/8905/5694/1104/2547/6882/2961/5432/22916/1234/6877/5905/3837/6917/81929/5440/164/5684/8065/5720/902/9631/3159/5430/5690/7520/5717/9491/6500/6749/79023/5441/23636/10197/7469/919/130340/4686/7316/10213/6872/53371/3055/9688/8731/6879/9150/5715/5701/2958/5437/5685/8815/5686/6827/2968/5716/375/138474/1022/5693/5721/8178/8480/291 209 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2555396 Mitotic Metaphase and Anaphase 186/4699 202/10654 2.3731025096591988e-48 2.7765299363012627e-46 1.1282645265221807e-46 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/5520/81027/51529/4001/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/7444/5698/5692/5713/91687/119504/11243/10376/5710/7324/83540/2010/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/26271/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/7443/1781/7316/10213/4085/55166/5715/5701/5685/8815/5686/79003/9126/9232/5527/9700/5716/701/57551/5693/5721 186 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-68882 Mitotic Anaphase 185/4699 201/10654 5.062031323644557e-48 5.454986957893183e-46 2.216676361656999e-46 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/5520/81027/51529/4001/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/7444/5698/5692/5713/91687/119504/11243/10376/5710/7324/83540/2010/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/7443/1781/7316/10213/4085/55166/5715/5701/5685/8815/5686/79003/9126/9232/5527/9700/5716/701/57551/5693/5721 185 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2467813 Separation of Sister Chromatids 177/4699 190/10654 5.4394456845088714e-48 5.454986957893183e-46 2.216676361656999e-46 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/81027/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/5698/5692/5713/91687/119504/11243/10376/5710/7324/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7280/1778/5516/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/1781/7316/10213/4085/55166/5715/5701/5685/5686/79003/9126/9232/5527/9700/5716/701/57551/5693/5721 177 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5633007 Regulation of TP53 Activity 154/4699 160/10654 3.121772729214461e-47 2.921979274544735e-45 1.1873689959538515e-45 6884/6875/5563/83990/64769/9156/1763/1459/7486/6874/133383/9212/5982/1460/11200/472/53632/79813/639/28996/84289/1457/6790/29117/4194/5928/1432/4683/56950/84126/1107/8900/6873/5371/2475/672/6881/51616/5518/6117/11198/7159/51230/83695/7314/5515/1263/23368/23774/6118/3622/6446/51422/117584/116028/890/983/5519/27154/5458/83860/57459/10000/5985/900/7994/3066/7157/5984/6233/10419/5600/6883/7874/5608/5884/5810/26155/26013/253260/5170/80010/7862/1029/5457/9219/8445/204851/6878/5931/580/11073/80196/54971/641/1108/8148/64223/6119/3364/5571/10524/54457/144715/1616/6794/54815/94241/1111/8626/208/79109/7311/7161/5562/6880/6908/5983/5564/6882/5565/1020/53615/6877/5516/1017/9891/5305/5883/25946/10111/207/22974/6749/545/8550/7316/6872/6879/112858/10848/9099/2033/3065/91875/5527/5932/8851/5300/7156/138474/133746/10919/4193 154 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9006925 Intracellular signaling by second messengers 253/4699 305/10654 1.1895714366597005e-45 1.0438489356688872e-43 4.241761307036564e-44 5295/1912/2308/5689/374/3725/6591/3643/2250/5335/5682/5291/1822/1459/5526/9112/817/6045/5578/5582/27327/80012/3082/1460/941/143471/2064/5705/5709/5695/107/1457/1911/4734/5711/5928/5683/2534/23512/9965/57332/5699/2444/2264/3630/5702/192669/1107/3654/5371/9542/2885/2475/51135/8660/5518/1386/2252/4343/80351/5696/814/5691/7314/5879/5515/5718/818/5290/3667/8823/90865/2065/23186/5700/3815/122706/5707/5567/2146/51564/5594/84335/84232/8074/7249/23198/112/57761/2260/5573/5528/111/2249/6714/2099/9861/7101/81847/2248/5519/2932/84733/57459/2247/5698/10000/5692/5713/5710/3066/7157/5613/5719/6233/5580/7409/2246/2251/3932/2931/331/8726/196883/115/26523/7874/801/5781/57521/23608/940/6015/253260/28956/5170/3838/572/9219/8535/4303/5568/930/5931/5706/6199/113/2263/4233/8658/5714/1108/2122/64223/5566/10014/8503/5688/5159/5687/29851/5708/3084/54815/5529/816/7189/208/5577/5704/10718/79109/55004/57504/7311/5293/1956/648/2549/5694/23466/53615/109/5595/5516/1147/27161/815/5684/8841/5305/5720/2309/5468/5525/5575/842/5978/8870/10273/207/5690/57690/5717/1027/9491/8817/114/10197/108/192670/4615/2100/2254/7316/10213/152831/1950/1026/50852/10768/26281/57167/10818/5715/1958/2261/5701/5576/5685/2255/8649/3164/5686/5728/6615/3065/2066/27006/23028/942/5987/23112/10542/5527/5716/1385/5296/5581/5693/5721/5156/4193 253 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69620 Cell Cycle Checkpoints 245/4699 293/10654 1.7959246474716784e-45 1.4832224735589627e-43 6.027189838573684e-44 5689/55839/11130/9134/83990/11065/6249/5682/9156/57060/9735/1763/7531/7486/7321/5526/10971/8697/9212/5982/7533/2810/147841/348995/11200/143471/472/57122/5705/1780/23122/5048/5709/4174/5695/57405/8655/84515/23279/4194/4998/5711/2491/4683/10926/5683/990/1060/165918/84126/5699/5702/8900/51529/29945/8924/11004/51434/55388/672/9184/5518/6117/29882/7334/5001/23332/7465/25909/51230/10726/81930/55746/5696/83695/5691/7314/996/5515/5718/6118/79682/10403/23594/25936/5700/122706/5707/51588/51720/3619/23198/63967/898/64105/7534/332/5528/993/116028/890/983/51433/9861/79902/3796/9656/5519/81565/5698/5692/5985/5713/91687/119504/11243/4175/5710/7157/5984/7324/83540/5719/64682/6233/7514/7158/54820/6396/64946/9793/5884/5810/140735/4999/220134/4172/80010/4928/5903/5000/8318/246184/55055/51512/1029/80776/1783/401541/7532/79172/4173/5706/9133/79980/6232/580/8881/11073/891/5501/641/5714/54821/6119/9183/3364/10524/5688/1062/699/5687/144715/5708/22919/5529/51143/1111/10393/5704/23595/7311/25906/5347/84643/5983/5694/4176/7529/1778/5516/1017/5905/81929/5684/5720/54908/55143/5883/5525/25946/1058/991/79019/10111/8317/348235/80152/5690/1063/8379/5717/1027/9491/23421/545/55920/79023/10197/7336/1781/7316/10213/4085/1026/4171/55166/5715/9088/7341/5701/5685/5686/995/79003/5527/5716/701/5932/79184/57551/7156/5693/5721/4193 245 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-72172 mRNA Splicing 175/4699 191/10654 9.571008751567727e-45 7.465386826222827e-43 3.0336179785670816e-43 8449/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/5431/9092/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/22938/988/23020/6631/3181/5439/1660/9410/6638/3312/10907/10291/26121/10262/53981/6432/10084/6430/51340/6627/83443/11051/9129/9879/8106/51690/27238/55749/5438/85313/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/10236/10250/4670/51362/10465/55660/23283/2521/3191/10285/6636/23524/10914/8175/84950/3188/56259/5725/1994/10450/7536/2963/6635/5434/220988/6632/10283/24148/23350/5436/10523/6428/27258/6637/55110/5093/6429/57819/10181/2962/10898/10569/23658/6434/9295/84844/51692/10421/11193/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/51691/10946/27339/5430/79869/85437/11325/57703/3184/25804/29894/11017/51503/3178/5441/3183/10594/4686/8189/10713/10978/5546/7307/10772/5437/6629/10189/10949/51729/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/84991/10992/55339/6628 175 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1257604 PIP3 activates AKT signaling 223/4699 264/10654 6.43143132021039e-43 4.752489249250203e-41 1.9312109559856128e-41 5295/1912/2308/5689/374/3725/6591/3643/2250/5682/5291/1822/1459/5526/9112/6045/27327/80012/3082/1460/941/143471/2064/5705/5709/5695/1457/1911/4734/5711/5928/5683/2534/23512/9965/57332/5699/2444/2264/3630/5702/192669/1107/3654/5371/9542/2885/2475/51135/8660/5518/1386/2252/4343/80351/5696/5691/7314/5879/5515/5718/5290/3667/8823/90865/2065/23186/5700/3815/122706/5707/2146/51564/5594/84335/84232/8074/7249/23198/57761/2260/5528/2249/6714/2099/9861/7101/81847/2248/5519/2932/84733/57459/2247/5698/10000/5692/5713/5710/3066/7157/5719/6233/7409/2246/2251/3932/2931/331/8726/26523/7874/5781/57521/23608/940/6015/253260/28956/5170/572/9219/8535/4303/930/5931/5706/6199/2263/4233/8658/5714/1108/2122/64223/10014/8503/5688/5159/5687/29851/5708/3084/54815/5529/7189/208/5704/10718/79109/55004/57504/7311/5293/1956/648/2549/5694/23466/53615/5595/5516/1147/27161/5684/8841/5305/5720/2309/5468/5525/842/5978/8870/10273/207/5690/57690/5717/1027/9491/8817/10197/192670/4615/2100/2254/7316/10213/152831/1950/1026/50852/26281/57167/10818/5715/1958/2261/5701/5685/2255/8649/3164/5686/5728/6615/3065/2066/27006/23028/942/5987/23112/10542/5527/5716/1385/5296/5693/5721/5156/4193 223 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5683057 MAPK family signaling cascades 240/4699 294/10654 5.741989681185082e-41 4.030876756191927e-39 1.63797810905385e-39 2308/5689/374/2118/3725/5897/2674/4893/6711/2250/1437/71/5682/1844/1850/1848/5526/817/84292/27327/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/22866/5605/4609/5037/5711/3558/3717/2244/54756/5683/2534/3690/408/9965/5699/2264/5702/192669/4296/5894/1847/3563/9542/2885/6709/8660/8997/8826/5518/2252/1740/4140/4343/3845/3265/4763/3569/5062/5696/5691/7314/3572/5879/5515/5923/5718/818/3667/8823/2065/5700/3815/122706/5707/5567/8844/7094/1849/1439/5594/8074/23198/7414/5921/3337/2260/5528/983/3718/2249/6714/9861/2248/5519/3567/148170/2247/5698/5692/10435/5713/2335/80824/1445/5710/8555/896/5719/6233/2266/2246/7514/2251/2243/1843/3570/26523/369/801/200734/7297/5781/8682/10602/1846/11221/28956/9462/3562/6464/2904/5747/283455/3674/7010/5568/3315/409/5706/1438/673/2263/4233/5597/84078/5714/5566/5688/5159/5687/5708/3084/5063/5529/816/998/9693/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/5058/7529/5595/5516/27161/815/5684/5720/2309/5604/3561/5525/153090/10642/10048/5690/57690/5717/9491/3568/8817/10197/192670/5596/8550/54518/2254/7316/10213/152831/1950/3560/26281/10818/5715/10256/2261/5701/27040/5685/2255/8649/5686/2066/6708/27006/8556/5979/23112/5527/5716/5906/5896/399473/3559/8202/5693/5721/5245/5156/161742 240 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69242 S Phase 149/4699 161/10654 1.371469427986945e-39 9.169252747112718e-38 3.725997142701375e-38 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/10274/5925/143471/5705/5709/5422/9978/1869/4174/5753/5695/84515/4609/4998/5711/5928/5683/990/5699/5702/8900/51529/29945/51434/157570/6117/29882/5001/10714/7465/5696/5691/7314/996/5718/6118/23594/7027/5700/122706/5707/23198/898/3978/91768/5934/5557/993/890/51433/9861/2932/6502/5698/10000/5692/5985/5713/119504/595/4175/5710/5984/7324/5719/64682/6233/113130/23649/1163/5424/4999/4172/1019/5000/8318/246184/54107/4173/5706/286826/23047/8881/5885/4331/5425/5714/5111/6119/5688/5687/5427/5708/1874/8243/81620/10393/208/5704/55957/51343/23595/7311/25906/51659/5983/5694/4176/56655/1017/5684/994/5720/902/207/9837/5690/5717/1027/9491/6500/23244/10735/10197/4149/7316/10213/1026/4171/5715/5701/5685/5686/9126/5716/5981/1022/5693/5721 149 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-453279 Mitotic G1-G1/S phases 140/4699 149/10654 2.567551248148744e-39 1.6385645238185621e-37 6.658434337304398e-38 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/1031/4998/5711/5928/10926/3717/5683/990/5699/5702/5520/8900/55388/28227/1030/5518/6117/5001/7465/5696/5691/7314/5515/6241/5718/6118/25/23594/7027/5700/5707/7153/898/91768/5934/5557/993/890/1876/983/6714/9861/5519/6502/5698/10000/5692/5713/595/4175/5710/896/5719/6233/7298/23649/1719/1163/1859/4999/4172/26271/1019/5000/8318/1029/54107/4173/5706/286826/891/4331/5714/5111/51053/6119/5688/5687/5427/4067/5708/1874/81620/208/1870/5704/55957/23595/7311/5694/4176/5516/56655/1017/894/5684/5720/4605/902/8317/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1026/5933/4171/1871/5715/5701/5685/5686/1021/3065/5716/1022/5693/5721/7083/1028 140 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8856828 Clathrin-mediated endocytosis 137/4699 146/10654 2.6033124512466305e-38 1.5891524702392473e-36 6.457644615906975e-37 5869/374/85439/71/8674/5286/4738/1212/23208/27348/1785/29763/950/8871/10094/554/54874/55738/10980/22848/7037/2017/3482/408/9322/10987/6456/185/8976/30011/2885/163/11037/1759/23149/3312/29993/9185/7314/9856/161/7018/25977/5868/10618/10093/8027/1856/9892/8322/2060/1601/6453/55707/8301/1129/9146/6455/4074/10920/26119/29979/6233/90019/7474/6844/1213/2580/1211/29924/4036/1175/85021/10109/6869/1173/6857/84251/23048/9026/29988/409/112574/382/160/338/8218/920/22905/26052/8867/10092/9829/2873/10097/7311/1956/60/8533/274/51429/8673/3092/50618/51138/9318/127833/1080/29978/58513/7316/1950/273/64708/10552/26130/3267/3949/867/9341/915/917/6572/115548/5878/1861/10096/143425/3575/6845/551/154/10254/6457/50813/4952/11252 137 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-162909 Host Interactions of HIV factors 122/4699 129/10654 3.3653734550611465e-35 1.9687434712107706e-33 8.000142160715532e-34 23165/5689/162/5682/1174/348995/143471/57122/5705/23511/5709/9978/5695/292/567/23279/5711/23225/5683/2534/5699/5702/3836/163/9972/8021/904/55690/5062/55746/5696/5691/7314/5879/5718/8945/51606/161/5700/122706/5707/10053/23198/10762/926/9861/79902/11168/9883/5698/5692/5713/5710/5902/5478/5719/6233/7514/1025/3932/6396/129401/1175/8907/940/60489/1173/4928/5903/55706/7175/4869/5706/160/293/920/5714/4927/5688/5687/5708/5901/8086/5704/7311/8905/5694/1104/5905/3837/81929/164/5684/8065/5720/9631/3159/5690/5717/9491/6500/79023/23636/10197/919/130340/7316/10213/53371/3055/9688/5715/5701/5685/8815/5686/5716/375/5693/5721/8480/291 122 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69206 G1/S Transition 123/4699 131/10654 1.4402791342611296e-34 8.088607618010504e-33 3.28686859271382e-33 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/4998/5711/5928/10926/5683/990/5699/5702/8900/55388/28227/5518/6117/5001/7465/5696/5691/7314/5515/6241/5718/6118/23594/7027/5700/5707/898/91768/5934/5557/993/890/1876/983/9861/5519/6502/5698/10000/5692/5713/595/4175/5710/5719/6233/7298/23649/1719/1163/4999/4172/26271/1019/5000/8318/54107/4173/5706/286826/891/4331/5714/5111/51053/6119/5688/5687/5427/5708/1874/81620/208/5704/55957/23595/7311/5694/4176/5516/56655/1017/5684/5720/902/8317/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1026/5933/4171/5715/5701/5685/5686/3065/5716/1022/5693/5721/7083 123 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69306 DNA Replication 120/4699 127/10654 1.5915970283600187e-34 8.594623953144102e-33 3.492492264660446e-33 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/143471/5705/5709/5422/9978/1869/4174/5695/84515/4998/5711/10926/5683/990/5699/5702/8900/51529/29945/51434/55388/6117/29882/5001/10714/5696/5691/7314/996/5718/6118/23594/5700/122706/5707/23198/898/3978/5557/890/51433/9861/6502/5698/5692/5985/5713/119504/4175/5710/5984/7324/5719/64682/6233/23649/5424/4999/4172/5000/8318/246184/54107/4173/5706/8881/5425/5714/5111/51053/6119/5688/5687/5427/5708/81620/10393/1870/5704/51343/23595/7311/25906/51659/5983/5694/4176/56655/1017/5684/5720/8317/9837/5690/5717/9491/6500/10197/7316/10213/4171/1871/5715/5701/5685/5686/5716/5981/5693/5721 120 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-168254 Influenza Infection 140/4699 155/10654 3.046611374597222e-34 1.5842379147905553e-32 6.437673937745398e-33 3839/6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/23279/23225/6192/6156/6143/5439/3836/6139/9972/3921/8021/7040/55746/6208/6170/3303/6203/6147/6222/8106/9636/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/7514/1213/5610/1211/6188/6396/129401/200916/6122/6230/4928/2963/3838/5434/5903/6194/55706/7175/5436/6136/6125/821/6232/6160/293/5611/6193/4927/6210/6229/6205/2962/10898/3840/140801/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/81929/5440/9349/4736/51121/9631/6217/3843/5430/6152/51065/6141/79023/5441/23636/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 140 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69239 Synthesis of DNA 113/4699 119/10654 3.687130579755211e-33 1.8488326192772558e-31 7.512875091080167e-32 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/143471/5705/5709/5422/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/6117/29882/5001/10714/5696/5691/7314/996/5718/6118/23594/5700/122706/5707/23198/898/3978/5557/890/51433/9861/6502/5698/5692/5985/5713/119504/4175/5710/5984/7324/5719/64682/6233/23649/5424/4999/4172/5000/8318/246184/54107/4173/5706/8881/5425/5714/5111/6119/5688/5687/5427/5708/81620/10393/5704/51343/23595/7311/25906/51659/5983/5694/4176/56655/1017/5684/5720/9837/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5981/5693/5721 113 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-168255 Influenza Life Cycle 131/4699 144/10654 6.63594570362744e-33 3.2127130234113538e-31 1.3055109151963966e-31 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/23279/23225/6192/6156/6143/5439/3836/6139/9972/3921/8021/55746/6208/6170/3303/6203/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/7514/1213/1211/6188/6396/129401/200916/6122/6230/4928/2963/5434/5903/6194/55706/7175/5436/6136/6125/821/6232/6160/5611/6193/4927/6210/6229/6205/2962/140801/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/81929/5440/9349/4736/51121/9631/6217/3843/5430/6152/51065/6141/79023/5441/23636/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 131 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9607240 FLT3 Signaling 211/4699 267/10654 3.4615901986395726e-32 1.62002421296332e-30 6.58309434267596e-31 5295/5689/374/2674/4893/6711/2250/1437/71/5682/1844/5291/1850/1848/5526/817/84292/5908/3082/143471/2064/5705/8452/6776/4684/5709/9978/5695/1852/2668/22866/5605/5037/5711/3558/3717/2244/54756/5683/2534/3690/408/9965/5699/2264/5702/4296/5894/1847/3563/9542/2885/6709/8660/8826/9846/5518/2252/1740/4140/3845/3265/4763/5696/5691/7314/5515/54106/5923/5718/818/5290/3667/8823/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/8074/23198/7414/57761/5921/2260/5528/3718/2249/6714/9861/2248/5519/3567/2247/5698/5692/5713/2335/80824/1445/5710/5719/6233/2266/2246/2251/2243/1843/6777/369/801/200734/5781/30849/8682/1846/11221/28956/5170/9462/3562/6464/2904/5747/283455/3674/7010/409/5706/1438/673/2263/4233/84078/5714/5688/5159/5687/5708/3084/5529/816/9693/208/6654/5704/10718/3716/7311/7450/1956/60/5536/2549/5694/7529/5595/5516/815/5684/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10197/54518/2254/7316/10213/152831/1950/3560/3055/26281/10818/5715/10256/2261/5701/27040/5685/2255/8649/5686/2066/6708/27006/5979/5527/5716/5906/5296/399473/3559/5693/5721/5245/5156/161742 211 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 91/4699 92/10654 1.425072851557022e-31 6.454200914793738e-30 2.6227147217110558e-30 6884/6875/5563/83990/9156/1763/1459/7486/6874/9212/5982/1460/11200/472/53632/28996/1457/6790/4194/1432/4683/84126/8900/6873/672/6881/51616/6117/11198/83695/7314/1263/6118/51422/116028/890/83860/5985/7157/5984/6233/5600/6883/5884/5810/26155/80010/8445/204851/6878/580/11073/641/8148/6119/3364/5571/10524/54457/144715/6794/94241/1111/7311/5562/6880/6908/5983/5564/6882/5565/1020/6877/1017/9891/5883/10111/22974/6749/545/8550/7316/6872/6879/112858/5932/8851/5300/7156/138474/4193 91 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5684996 MAPK1/MAPK3 signaling 202/4699 255/10654 4.0631185264128186e-31 1.782693253463624e-29 7.244112635907065e-30 5689/374/2674/4893/6711/2250/1437/71/5682/1844/1850/1848/5526/817/84292/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/22866/5605/5037/5711/3558/3717/2244/54756/5683/2534/3690/408/9965/5699/2264/5702/4296/5894/1847/3563/9542/2885/6709/8660/8826/5518/2252/1740/4140/3845/3265/4763/3569/5696/5691/7314/3572/5515/5923/5718/818/3667/8823/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/8074/23198/7414/5921/2260/5528/983/3718/2249/6714/9861/2248/5519/3567/2247/5698/5692/5713/2335/80824/1445/5710/5719/6233/2266/2246/2251/2243/1843/3570/369/801/200734/7297/5781/8682/1846/11221/28956/9462/3562/6464/2904/5747/283455/3674/7010/409/5706/1438/673/2263/4233/84078/5714/5688/5159/5687/5708/3084/5529/816/9693/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/7529/5595/5516/815/5684/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10197/54518/2254/7316/10213/152831/1950/3560/26281/10818/5715/10256/2261/5701/27040/5685/2255/8649/5686/2066/6708/27006/5979/5527/5716/5906/399473/3559/5693/5721/5245/5156/161742 202 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69052 Switching of origins to a post-replicative state 89/4699 90/10654 7.322879426662248e-31 3.115552337889029e-29 1.2660289152315594e-29 8454/5689/9134/11065/5682/7321/8697/143471/5705/5709/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/29882/5001/5696/5691/7314/996/5718/23594/5700/122706/5707/23198/898/890/51433/9861/6502/5698/5692/5713/119504/4175/5710/7324/5719/64682/6233/4999/4172/5000/246184/4173/5706/8881/5714/5688/5687/5708/81620/10393/5704/51343/23595/7311/25906/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 89 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69618 Mitotic Spindle Checkpoint 106/4699 112/10654 8.576327392772532e-31 3.5415187233684225e-29 1.439123667765546e-29 55839/11130/11065/6249/9735/7321/5526/8697/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/996/5515/79682/10403/25936/3619/64105/332/5528/51433/79902/3796/5519/81565/91687/119504/11243/7324/83540/64682/7514/54820/6396/64946/9793/140735/220134/4928/5903/246184/55055/80776/1783/401541/79172/79980/6232/8881/5501/54821/9183/1062/699/22919/5529/51143/10393/25906/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/55166/79003/5527/701/57551 106 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-202403 TCR signaling 111/4699 119/10654 1.4224183748731211e-30 5.705929709491035e-29 2.3186488997931782e-29 5295/8454/5689/5335/4790/5682/5291/7321/143471/5705/5788/3115/5709/5695/4792/3113/5711/3117/5683/55824/5699/5702/26191/3127/7334/3551/5062/5696/5691/7314/5718/8945/3635/5290/5700/122706/5707/8767/23198/23118/10892/8517/5970/9861/5588/5698/5692/5713/1445/5710/916/5719/6233/3702/3932/3120/5170/3937/3123/5706/3122/920/8915/5714/5795/5688/5687/5708/5063/7189/7535/5704/7311/5694/5058/997/1147/55740/9402/5684/5720/6885/4690/3119/84433/5690/5717/9491/6500/10197/919/7316/10213/7335/50852/7322/5715/5701/27040/23291/915/5685/917/51466/5686/7408/5728/5716/5296/5693/5721 111 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6807070 PTEN Regulation 126/4699 140/10654 1.507838122527418e-30 5.88056867785693e-29 2.3896148023680132e-29 1912/5689/3725/6591/5682/1822/1459/9112/6045/27327/80012/1460/143471/5705/5709/5695/1457/1911/4734/5711/5928/5683/23512/57332/5699/2444/5702/192669/1107/5371/2475/1386/4343/80351/5696/5691/7314/5718/23186/5700/122706/5707/2146/51564/5594/84232/23198/9861/7101/81847/84733/57459/5698/10000/5692/5713/5710/3066/7157/5719/6233/331/8726/26523/7874/57521/23608/6015/28956/9219/8535/5931/5706/8658/5714/1108/2122/64223/10014/5688/5687/5708/54815/208/5704/55004/57504/7311/648/5694/23466/53615/5595/27161/5684/8841/5720/5468/5978/10273/207/5690/57690/5717/9491/10197/192670/7316/10213/57167/5715/1958/5701/5685/8649/5686/5728/6615/3065/23028/5987/23112/10542/5716/5693/5721 126 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-418594 G alpha (i) signalling events 291/4699 406/10654 2.0365649113519462e-30 7.727938204157115e-29 3.1403077722695734e-29 729230/2788/10316/1880/7852/50833/29899/6385/5726/338442/64805/2770/817/1237/2550/5578/50832/3354/2841/5582/4987/51289/259294/8644/2912/3576/6360/2775/5530/4985/2920/2921/1236/259295/107/9568/2840/2831/5367/4988/6370/58191/5475/6755/1524/643/2782/5996/5499/339403/4023/2914/8843/2847/2833/10636/9290/5518/9170/6382/187/6750/259296/259289/50835/2587/53829/814/2773/5515/2787/6387/818/4544/4543/126006/10663/4889/9283/727/338398/117579/3579/84152/23566/2358/5567/2916/259293/5594/5179/10681/5142/112/1645/8811/5573/348/56923/2832/5528/27199/2826/6376/165140/27198/111/5443/4836/3627/2792/9397/54429/6714/336/3361/6346/10988/5519/134/5588/1129/338328/51083/2785/2783/2784/1233/6366/5613/2861/2771/728/183/10022/5580/6373/57121/1132/1814/80835/4036/6357/196883/9672/115/8698/801/9934/50840/2791/50865/10803/2913/3838/7276/351/11251/3352/8484/6351/6752/2781/1903/84539/6753/5568/3577/2918/5368/6754/8862/301/56670/150/113/338/335/2853/6751/186/53637/5566/10563/5540/1901/10287/5733/256933/10850/624/4852/816/8601/2786/50838/5577/5473/4283/11255/10874/83756/2719/56477/1020/5141/259286/3350/129521/1234/109/5516/151/57007/5533/815/26086/5321/9294/54331/283869/5575/59345/63940/4986/6374/5539/259287/2852/50836/1230/5532/846/4886/2919/51764/94235/114/259290/57016/6383/108/5196/3827/5173/2357/55970/2778/6352/140/10768/346562/152/6364/80834/259292/3949/2793/5030/5697/5576/3355/5534/3351/4035/6288/6372/50834/259285/1385/5144/719/6363/2917/1268/50831/2359/50839/5660/1815/1325/1232/1902/50837/1269/59340/4887/2790/718/6003/623 291 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-68877 Mitotic Prometaphase 166/4699 200/10654 2.73001762000279e-30 1.0086696680220834e-28 4.098807617843524e-29 10844/55839/11130/6249/9735/7531/1459/11190/203068/5526/54801/51807/9212/347688/10274/1460/147841/348995/79441/10381/57122/5116/1780/23122/5048/57405/8655/1457/23279/2491/7846/1060/11064/81027/11004/9184/5518/55835/23332/25909/10726/81930/55746/93323/5515/79682/10403/64151/25936/55869/1454/3619/64105/332/10051/5528/983/79902/3796/5519/81565/80097/91687/11243/10376/23397/10540/83540/7514/54930/54820/113130/6396/1453/27229/64946/9793/140735/220134/84617/4928/5903/22981/55055/80776/1783/401541/7532/10382/79172/121441/7277/9133/79980/6232/23047/5885/23354/891/5501/9738/1639/4957/5566/54821/9183/1062/699/7283/22919/8243/10426/5529/51143/1069/5577/10383/5347/84790/84643/80184/22897/10592/7280/1778/5516/115106/4926/5905/22995/55559/81929/54908/55143/5525/10142/1058/991/79019/348235/80152/1063/8379/95681/23244/23421/55920/79023/10735/1781/4085/55166/10121/84131/3320/79003/9126/9918/10733/4751/5527/701/57551/9662/55142/8481 166 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 87/4699 88/10654 3.7592702166887554e-30 1.353337278007952e-28 5.499391248165467e-29 5393/5689/5682/23404/5578/26986/143471/5705/5709/5695/5711/1432/5683/5699/5702/11340/8021/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/7534/9261/8741/9861/5698/5692/5713/1981/5710/5719/6233/5580/7514/5600/8570/23016/118460/1994/5073/3842/3315/5706/8125/677/7538/5714/5688/5687/5708/5704/7311/51010/5694/56915/3304/6418/167227/7529/22894/5684/5720/207/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/55802/51013/5716/54464/5693/54512/5721 87 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-68886 M Phase 284/4699 395/10654 4.458072211712612e-30 1.564783346311127e-28 6.358618786179568e-29 10844/23165/5689/55839/11130/11065/6249/5579/5682/9735/7531/1459/11190/7321/91754/203068/5526/54801/51807/8697/5578/9212/347688/10274/5861/5925/1460/147841/348995/79441/143471/10381/57122/5705/5116/1780/23122/23511/5048/5709/5695/57405/8655/1457/23279/5711/2491/10112/7846/23225/5683/1060/5699/11064/5702/5520/81027/51529/4001/29945/11004/51434/9184/9972/5518/55844/55835/8021/29882/23332/25909/10726/81930/55746/93323/5696/5691/7314/996/5515/5718/79682/10403/64151/25936/55869/5700/122706/5707/1454/2801/5594/3619/23198/64105/23310/332/10762/10051/5528/983/8548/51433/9861/79902/3796/8615/5519/9883/81565/7444/5698/5692/5713/80097/91687/119504/11243/10376/23397/5710/10540/7324/83540/2010/64900/5719/64682/6233/23175/7514/54930/54820/113130/9493/6396/129401/1453/27229/64946/9793/140735/220134/84617/4928/26271/5903/55706/7175/22981/246184/55055/80776/1783/401541/7532/10382/79172/121441/7277/5706/9133/79980/6232/23047/8881/5885/23354/255919/891/5501/9738/1639/5714/4957/4927/5566/54821/9183/5688/1062/699/5687/7283/5708/22919/8243/10426/5529/51143/1069/8086/10393/79648/5577/5704/7311/25906/10383/5347/84790/84643/80184/5694/22897/6418/7112/10592/7280/29781/5595/1778/5516/4000/115106/4926/5905/22995/55559/81929/5684/5720/54908/55143/9631/5525/10142/1058/991/79019/5862/348235/80152/5690/1063/8379/95681/5717/9491/140609/10783/23244/23421/55920/79023/23636/10735/10197/7443/1781/7316/10213/53371/26003/4085/9688/55166/10121/5715/84131/5701/5685/3320/8815/5686/79003/9126/9918/10733/23399/4751/9232/5527/9700/5716/701/57551/9662/55142/64689/8481/5693/5721/8480 284 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5357801 Programmed Cell Death 153/4699 181/10654 8.438581752651163e-30 2.889699702615179e-28 1.1742519409337435e-28 5689/5682/4976/7531/356/10971/10059/7533/2810/143471/5705/5709/1869/5695/8655/5711/836/5683/929/324/5699/9414/5702/4001/3836/6709/6093/840/7159/26060/637/5062/5696/5691/7314/578/23368/5718/2934/11035/22985/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/7082/5339/4836/8797/9861/28988/10134/22900/999/5588/598/5698/10000/5692/708/5713/5710/3002/7157/5719/6233/5580/1613/839/8772/331/8717/57099/317/8743/140735/1828/5747/1029/572/7532/330/118/5706/6774/5366/5714/8428/5688/5687/1832/5708/8837/8626/208/5704/7311/7161/5694/8795/7529/5595/23643/4000/5533/27113/3837/596/5684/5720/7186/51765/1499/10018/842/207/5690/5717/9491/355/10197/7099/9500/7316/10213/54205/3146/5715/23604/5701/329/5685/5686/5534/4137/5716/1677/1630/581/5599/353376/7431/5693/5721/6304/148022 153 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-109581 Apoptosis 151/4699 178/10654 8.80193295650229e-30 2.942360445459337e-28 1.1956510432140957e-28 5689/5682/4976/7531/356/10971/10059/7533/2810/143471/5705/5709/1869/5695/8655/5711/836/5683/929/324/5699/9414/5702/4001/3836/6709/6093/840/7159/26060/637/5062/5696/5691/7314/578/23368/5718/2934/22985/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/7082/5339/4836/8797/9861/28988/10134/22900/999/5588/598/5698/10000/5692/708/5713/5710/3002/7157/5719/6233/5580/1613/839/8772/331/8717/57099/317/8743/140735/1828/5747/1029/572/7532/118/5706/6774/5366/5714/8428/5688/5687/1832/5708/8837/8626/208/5704/7311/7161/5694/8795/7529/5595/23643/4000/5533/27113/3837/596/5684/5720/7186/51765/1499/10018/842/207/5690/5717/9491/355/10197/7099/9500/7316/10213/54205/3146/5715/23604/5701/329/5685/5686/5534/4137/5716/1677/1630/581/5599/353376/7431/5693/5721/6304/148022 151 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-168273 Influenza Viral RNA Transcription and Replication 121/4699 134/10654 1.036674236961675e-29 3.3848619271957947e-28 1.3754649606688568e-28 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/23279/23225/6192/6156/6143/5439/6139/9972/3921/8021/55746/6208/6170/6203/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/6188/6396/129401/200916/6122/6230/4928/2963/5434/5903/6194/55706/7175/5436/6136/6125/6232/6160/5611/6193/4927/6210/6229/6205/2962/140801/6181/8086/7311/6223/25873/9045/6187/5432/6168/6157/6137/6144/81929/5440/9349/4736/51121/9631/6217/3843/5430/6152/51065/6141/79023/5441/23636/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 121 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5673001 RAF/MAP kinase cascade 196/4699 249/10654 1.519026741633646e-29 4.847076239212816e-28 1.9696471147498474e-28 5689/374/2674/4893/6711/2250/1437/71/5682/1844/1850/1848/5526/817/84292/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/22866/5605/5037/5711/3558/3717/2244/54756/5683/2534/3690/408/9965/5699/2264/5702/4296/5894/1847/3563/9542/2885/6709/8660/8826/5518/2252/1740/4140/3845/3265/4763/5696/5691/7314/5515/5923/5718/818/3667/8823/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/8074/23198/7414/5921/2260/5528/3718/2249/6714/9861/2248/5519/3567/2247/5698/5692/5713/2335/80824/1445/5710/5719/6233/2266/2246/2251/2243/1843/369/801/200734/8682/1846/11221/28956/9462/3562/6464/2904/5747/283455/3674/7010/409/5706/1438/673/2263/4233/84078/5714/5688/5159/5687/5708/3084/5529/816/9693/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/7529/5595/5516/815/5684/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10197/54518/2254/7316/10213/152831/1950/3560/26281/10818/5715/10256/2261/5701/27040/5685/2255/8649/5686/2066/6708/27006/5979/5527/5716/5906/399473/3559/5693/5721/5245/5156/161742 196 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 85/4699 86/10654 1.927935828548001e-29 5.884395441916073e-28 2.3911698376956905e-28 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 85 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-453276 Regulation of mitotic cell cycle 85/4699 86/10654 1.927935828548001e-29 5.884395441916073e-28 2.3911698376956905e-28 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 85 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-168898 Toll-like Receptor Cascades 135/4699 155/10654 3.168652130287376e-29 9.46550551260314e-28 3.846381757258136e-28 8454/3725/9252/4790/7321/1848/1785/6280/10333/4792/177/1432/2244/929/3654/51135/6196/1759/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/54106/11035/8945/1326/5601/6283/5606/8737/8767/5336/1849/29110/5594/4214/23118/841/8517/5528/7323/1515/5970/7096/9261/5519/5598/4208/6195/10454/3661/6233/51311/10010/2266/2353/2243/8772/5600/5781/30849/5608/4791/671/1508/1846/1514/3665/351/81793/7184/3684/8411/330/51295/7098/338/79155/6279/8651/26052/7867/64127/5602/3656/57162/695/7189/81622/7311/6416/51284/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7100/7316/7335/1513/4205/4793/5641/3146/7322/329/466/23291/114609/6288/2002/6285/5609/1520/1385/5599/353376/7097/57161/3689/148022 135 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-376176 Signaling by ROBO receptors 176/4699 218/10654 4.0248203785244037e-29 1.1772599607183881e-27 4.7838873797373405e-28 6158/5689/6138/6227/7852/6206/6234/6191/6128/5682/6132/57522/10298/6129/6176/5578/6224/6146/6154/26986/143471/6202/5705/6169/23122/5709/9978/6175/6218/5695/65109/5711/5683/6192/6156/5699/6143/5702/6139/10487/8440/3921/23332/5062/6208/5696/6170/5691/7314/5879/6387/5718/25/6203/8861/6147/5700/122706/5707/5567/6222/23198/26019/2935/6134/22794/6155/4116/6714/6231/9861/6142/23521/5698/5692/5713/1981/5710/6207/5719/6233/6188/200916/6122/6230/6194/2107/6136/5568/6125/5706/3670/6232/6160/55110/5714/6193/6210/6229/6205/5566/5688/5687/5708/5063/140801/6181/998/9939/6654/5704/7311/6223/25873/387/5694/5058/9045/6187/65110/6168/22916/6157/6137/4440/10921/6144/55740/23032/5684/9349/4736/5720/51121/4690/6217/6152/5690/5532/5717/9491/51065/6141/23053/10197/4686/7316/10213/5216/6209/11224/6165/6130/5715/6204/5701/6228/5576/5685/51466/5686/7408/6124/8453/5716/23380/1630/6189/9775/6135/6201/6161/5693/5721/6133/9901 176 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5687128 MAPK6/MAPK4 signaling 87/4699 89/10654 9.510443914185789e-29 2.725033317452418e-27 1.1073384750781308e-27 2308/5689/2118/3725/5897/5682/27327/143471/5705/5709/5695/4609/5711/5683/5699/5702/192669/8997/4343/5062/5696/5691/7314/5879/5718/5700/122706/5707/5567/23198/3337/983/9861/148170/5698/5692/10435/5713/5710/8555/896/5719/6233/7514/26523/10602/5568/3315/5706/5597/5714/5566/5688/5687/5708/5063/998/5704/7311/5694/5058/27161/5684/5720/2309/10642/5690/57690/5717/9491/10197/192670/5596/8550/7316/10213/5715/5701/5685/5686/8556/23112/5716/5896/8202/5693/5721 87 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 120/4699 134/10654 1.1716255990271294e-28 3.289924682068179e-27 1.3368864729951665e-27 5295/8454/5689/3725/4893/5335/4790/5682/5291/7321/143471/5705/5530/5709/5695/4792/5711/5683/2534/5699/5702/2885/9846/3845/7334/3265/3551/5062/5696/5691/7314/5879/257397/5718/8945/5601/4773/5290/5700/122706/5707/5336/5594/4214/23198/23118/10892/8517/5970/9861/5588/5698/5692/5713/5710/10454/5719/6233/7409/3702/2353/801/5170/6464/2205/4772/3937/4775/5706/2206/6850/8915/5714/5688/5687/4067/5708/5602/695/7189/6654/5704/7006/7311/5694/5058/6416/997/5595/1147/9402/5684/5720/6885/84433/5690/5532/5717/9491/6500/10197/7316/10213/7335/10768/7322/5715/5701/27040/23291/5685/5686/5534/5609/5716/5296/5599/5693/5721/2207 120 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9010553 Regulation of expression of SLITs and ROBOs 145/4699 171/10654 1.3363253029715348e-28 3.6788249517098726e-27 1.4949191211776512e-27 6158/5689/6138/6227/6206/6234/6191/6128/5682/6132/6129/6176/6224/6146/6154/26986/143471/6202/5705/6169/5709/9978/6175/6218/5695/65109/5711/5683/6192/6156/5699/6143/5702/6139/3921/6208/5696/6170/5691/7314/5718/6203/8861/6147/5700/122706/5707/6222/23198/26019/2935/6134/22794/6155/4116/6231/9861/6142/23521/5698/5692/5713/1981/5710/6207/5719/6233/6188/200916/6122/6230/6194/2107/6136/6125/5706/3670/6232/6160/55110/5714/6193/6210/6229/6205/5688/5687/5708/140801/6181/9939/5704/7311/6223/25873/5694/9045/6187/65110/6168/22916/6157/6137/4440/10921/6144/23032/5684/9349/4736/5720/51121/6217/6152/5690/5717/9491/51065/6141/23053/10197/4686/7316/10213/6209/11224/6165/6130/5715/6204/5701/6228/5685/5686/6124/8453/5716/6189/9775/6135/6201/6161/5693/5721/6133 145 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2500257 Resolution of Sister Chromatid Cohesion 114/4699 126/10654 3.043914083437638e-28 8.218568025281623e-27 3.3396790146218625e-27 55839/11130/6249/9735/5526/51807/9212/347688/10274/147841/348995/10381/57122/1780/23122/5048/57405/8655/23279/2491/7846/1060/81027/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/55869/3619/64105/332/5528/983/79902/3796/5519/81565/91687/11243/10376/83540/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/55055/80776/1783/401541/10382/79172/7277/9133/79980/6232/23047/5885/891/5501/54821/9183/1062/699/22919/8243/5529/51143/10383/5347/84790/84643/7280/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23244/23421/55920/79023/10735/1781/4085/55166/79003/9126/5527/701/57551 114 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2262752 Cellular responses to stress 328/4699 479/10654 3.166866487519553e-28 8.38920858203293e-27 3.409020131550343e-27 1912/23165/5689/3725/6782/9134/2077/11065/573/4790/5682/64344/7531/1915/7321/51807/817/6045/8697/9530/347688/23677/27327/80012/7295/5925/3091/348995/143471/472/10381/57122/5705/79813/3576/3313/1780/7001/23511/5709/9978/2114/1869/5695/3305/8655/1911/832/26277/23279/4194/1031/5711/5928/1432/1387/4683/7846/259217/23225/5683/3309/23512/57332/5699/126374/25994/7428/5702/192669/81027/8900/51529/4001/29945/8091/8131/2056/51434/2475/3306/1030/6196/9972/23411/8021/4343/6117/6197/29882/3312/4217/54386/3569/55746/5696/5691/7296/7314/996/51182/5718/818/3303/7014/6118/51606/5601/2876/5606/7027/5700/122706/5707/2146/2936/5594/3308/84335/23198/898/10049/10013/27244/3337/10762/847/7323/890/5970/9261/6667/51433/9861/79902/5598/9883/2932/84733/5698/5692/5713/2877/119504/10376/6195/5710/3301/10540/7157/7324/5719/64682/6233/2353/8726/6396/1535/129401/5600/26523/405/5608/3297/57521/140735/768/6015/28956/84617/4928/1019/5903/83667/55706/7175/653361/5241/9448/246184/112399/1029/1783/8535/84962/10382/5931/10294/55860/830/7013/7277/1051/1410/5706/8881/527/6774/1639/5714/4927/7867/64223/6119/26353/3552/10370/10524/5688/57805/5687/3310/2908/5708/5602/7266/25824/51143/816/6648/8086/10393/1870/5704/3326/55004/51343/7311/367/25906/2034/57634/10383/84790/55662/648/5694/3304/23466/3456/2113/6416/257202/7280/10728/829/2880/23523/5595/1778/1017/815/81929/5684/5720/9631/3159/7290/116835/10111/2878/7422/5690/57690/5717/1027/9491/545/79023/23636/10197/192670/10808/3490/8550/29855/1781/7316/10213/10935/53371/1026/9532/54205/2289/9588/9688/10121/7415/1871/8994/7322/5715/2882/5701/5685/8649/3320/65057/5686/2033/1021/25842/493869/8453/23135/10963/22824/23112/5609/10542/5716/9529/5599/54583/5052/96459/5693/5721/55466/2288/5034/8480/10919/51382/4193/2950/23043 328 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-453274 Mitotic G2-G2/M phases 162/4699 198/10654 3.667047181644528e-28 9.534322672275772e-27 3.874346145129307e-27 10844/8454/5689/5682/7531/11190/203068/54801/51807/63943/347688/51400/79441/143471/10381/5705/5116/5048/5709/9978/1869/5695/8655/6790/5711/5928/7846/5683/5699/11064/5702/5520/81027/8900/28227/5518/55835/23332/7465/93323/5696/5691/7314/5515/5718/8945/4659/5700/122706/5707/1454/23198/993/890/983/9861/5519/5698/5692/5713/80097/10376/5710/10540/7157/5719/6233/7514/54930/54820/1453/27229/9793/5500/84617/2305/22981/51512/7532/84962/10382/121441/7277/5706/9133/286826/23354/891/9738/4331/1639/5714/4957/5566/5688/5687/7283/5708/22919/10426/79866/1069/5577/5704/3326/55957/7311/10383/5347/84790/80184/5694/22897/4660/7280/1778/5516/115106/1017/22995/55559/5684/994/5720/4605/902/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/1781/7316/10213/1026/10121/1871/5715/84131/9088/5701/23291/5685/3320/5686/2033/995/10733/4751/5716/23194/9662/55142/1022/8481/5693/5721 162 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9020702 Interleukin-1 signaling 97/4699 103/10654 9.049248119116337e-28 2.3100262471344248e-26 9.386971254662307e-27 8454/5689/4790/5682/8878/143471/5705/5709/9978/5695/4792/177/5711/5683/5699/5702/3654/51135/7334/3551/5696/5691/7314/257397/5718/8945/1326/6283/5700/122706/5707/8767/23198/23118/8517/5970/9861/5698/5692/5713/5710/10454/5719/6233/7850/5608/4791/3557/351/54472/5706/79155/5714/64127/3552/5688/5687/5708/3656/57162/7189/5704/7311/5694/6416/3554/1147/5684/5720/6885/5604/4215/10392/5690/3553/5717/9491/6500/246330/10197/4615/7316/10213/7335/4793/3146/5715/5701/23291/5685/5686/6288/6285/5716/57161/5693/5721 97 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69275 G2/M Transition 160/4699 196/10654 1.305200752190377e-27 3.272324742991588e-26 1.3297346009157602e-26 10844/8454/5689/5682/7531/11190/203068/54801/51807/63943/347688/51400/79441/143471/10381/5705/5116/5048/5709/9978/5695/8655/6790/5711/5928/7846/5683/5699/11064/5702/5520/81027/8900/28227/5518/55835/23332/7465/93323/5696/5691/7314/5515/5718/8945/4659/5700/122706/5707/1454/23198/993/890/983/9861/5519/5698/5692/5713/80097/10376/5710/10540/7157/5719/6233/7514/54930/54820/1453/27229/9793/5500/84617/2305/22981/51512/7532/84962/10382/121441/7277/5706/9133/286826/23354/891/9738/4331/1639/5714/4957/5566/5688/5687/7283/5708/22919/10426/79866/1069/5577/5704/3326/55957/7311/10383/5347/84790/80184/5694/22897/4660/7280/1778/5516/115106/1017/22995/55559/5684/994/5720/4605/902/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/1781/7316/10213/1026/10121/5715/84131/9088/5701/23291/5685/3320/5686/2033/995/10733/4751/5716/23194/9662/55142/1022/8481/5693/5721 160 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-202424 Downstream TCR signaling 93/4699 98/10654 2.090804275387077e-27 5.07283069748288e-26 2.0613841940588702e-26 5295/8454/5689/4790/5682/5291/7321/143471/5705/3115/5709/5695/4792/3113/5711/3117/5683/5699/5702/3127/7334/3551/5696/5691/7314/5718/8945/3635/5290/5700/122706/5707/8767/23198/23118/10892/8517/5970/9861/5588/5698/5692/5713/5710/916/5719/6233/3932/3120/5170/3123/5706/3122/920/8915/5714/5688/5687/5708/7189/5704/7311/5694/997/1147/5684/5720/6885/3119/84433/5690/5717/9491/6500/10197/919/7316/10213/7335/50852/7322/5715/5701/23291/915/5685/917/5686/5728/5716/5296/5693/5721 93 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-162587 HIV Life Cycle 131/4699 152/10654 2.095613820897486e-27 5.07283069748288e-26 2.0613841940588702e-26 6884/23165/6875/2237/7852/27243/6874/348995/57122/3981/5431/23511/5435/5433/2960/51271/23279/23327/29082/23225/2965/5439/6873/3836/9972/6881/2967/51616/8021/11198/904/51497/55746/92421/7314/137492/25978/51160/2959/404672/10015/91782/5438/3978/10762/79720/51534/4836/9397/79902/11168/9883/83860/2068/5902/5478/6233/7514/1025/6396/129401/6883/7936/6829/2957/25920/4928/2963/5434/5903/55706/7175/5436/6878/920/4331/4927/8148/2966/2962/54457/8812/128866/905/2071/5901/8086/7311/93343/6880/6908/7251/1104/2547/6882/2961/5432/22916/1234/6877/5905/6917/81929/5440/902/9631/3159/5430/7520/6749/79023/5441/23636/7469/4686/7316/6872/53371/9688/8731/6879/9150/2958/5437/8815/6827/2968/138474/1022/8178/8480 131 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 79/4699 80/10654 2.5843936776786982e-27 6.149980887221852e-26 2.4990925482637906e-26 8454/5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 79 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 89/4699 93/10654 4.364980971035609e-27 1.0046611939891795e-25 4.0825188719608286e-26 8454/3725/9252/4790/1848/4792/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/6283/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/1846/3665/351/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/353376/57161/148022 89 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-975155 MyD88 dependent cascade initiated on endosome 89/4699 93/10654 4.364980971035609e-27 1.0046611939891795e-25 4.0825188719608286e-26 8454/3725/9252/4790/1848/4792/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/6283/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/1846/3665/351/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/353376/57161/148022 89 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 88/4699 92/10654 9.572260187149741e-27 2.167653758509393e-25 8.808429577988388e-26 8454/3725/9252/4790/1848/4792/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/6283/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/1846/351/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/353376/57161/148022 88 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-166166 MyD88-independent TLR4 cascade 93/4699 99/10654 1.9612188686738202e-26 4.302423893153193e-25 1.7483233993769914e-25 8454/3725/9252/4790/7321/1848/4792/177/1432/929/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/1326/5601/6283/5606/8737/8767/1849/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/1846/3665/351/330/79155/7867/64127/5602/3656/7189/7311/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/7316/7335/4205/4793/3146/7322/329/466/23291/6288/2002/6285/5609/1385/5599/353376/148022 93 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 93/4699 99/10654 1.9612188686738202e-26 4.302423893153193e-25 1.7483233993769914e-25 8454/3725/9252/4790/7321/1848/4792/177/1432/929/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/1326/5601/6283/5606/8737/8767/1849/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/1846/3665/351/330/79155/7867/64127/5602/3656/7189/7311/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/7316/7335/4205/4793/3146/7322/329/466/23291/6288/2002/6285/5609/1385/5599/353376/148022 93 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 98/4699 106/10654 2.689218684056423e-26 5.808712357561874e-25 2.36041542794912e-25 374/85439/8674/4738/1212/23208/27348/950/554/10980/22848/7037/3482/408/10987/6456/185/30011/2885/163/11037/23149/9185/7314/9856/161/7018/25977/10618/8027/1856/9892/8322/2060/1601/6453/55707/8301/1129/9146/6455/4074/10920/26119/29979/6233/90019/7474/6844/1213/1211/29924/4036/1175/85021/6869/1173/6857/84251/29988/409/160/338/8218/920/22905/2873/7311/1956/8533/8673/50618/51138/9318/127833/1080/29978/58513/7316/1950/64708/3267/3949/867/9341/915/917/6572/115548/1861/143425/3575/6845/551/154/10254/6457/50813 98 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8953897 Cellular responses to external stimuli 331/4699 493/10654 4.3822837827761564e-26 9.32231277426928e-25 3.788194274744301e-25 1912/23165/5689/3725/6782/9134/2077/11065/573/4790/5682/64344/7531/1915/7321/51807/817/6045/8697/9530/347688/23677/27327/80012/7295/5925/3091/348995/143471/472/10381/57122/5705/79813/3576/3313/1780/7001/23511/5709/9978/2114/1869/5695/3305/8655/1911/832/26277/23279/4194/1031/5711/5928/1432/1387/4683/7846/259217/23225/5683/3309/23512/57332/5699/126374/25994/7428/5702/192669/81027/8900/51529/4001/29945/8091/8131/2056/51434/2475/3306/1030/6196/9972/23411/8021/4343/6117/6197/29882/3312/4217/54386/3569/55746/5696/5691/7296/7314/996/51182/5718/818/3303/7014/6118/51606/5601/2876/5606/7027/5700/122706/5707/2146/2936/5594/3308/84335/23198/898/10049/10013/27244/3337/10762/847/7323/1465/890/5970/9261/6667/51433/9861/79902/5598/9883/2932/84733/5698/5692/5713/2877/119504/10376/6195/5710/3301/10540/7157/7324/5719/64682/6233/2353/8726/6396/1535/129401/5600/26523/405/5608/3297/57521/140735/768/6015/28956/84617/4928/1019/5903/83667/55706/7175/653361/5241/9448/246184/112399/1029/1783/8535/84962/10382/5931/10294/55860/830/7013/7277/1051/1410/5706/8881/527/6774/1639/5714/4927/7867/64223/6119/26353/3552/10370/10524/5688/57805/5687/3310/2908/5708/5602/7266/25824/51143/816/6648/8086/10393/1870/5704/3326/55004/51343/7311/367/25906/2034/57634/10383/84790/55662/648/5694/3304/23466/3456/2113/6416/257202/7280/10728/829/2880/23523/5595/1778/1017/815/81929/5684/5720/9631/3159/7290/116835/10111/4502/2878/7422/5690/57690/5717/1027/9491/545/79023/23636/10197/192670/10808/3490/8550/29855/1781/7316/10213/10935/53371/1026/9532/54205/2289/9588/9688/10121/7415/1871/8994/7322/5715/2882/5701/5685/8649/3320/65057/5686/2033/1021/25842/493869/8453/23135/10963/22824/23112/5609/10542/5716/9529/4520/5599/54583/5052/96459/5693/5721/55466/2288/5034/8480/10919/51382/4193/2950/23043 331 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 89/4699 94/10654 4.6652663866436386e-26 9.776170159474133e-25 3.972622751863083e-25 8454/3725/9252/4790/7321/1848/4792/177/1432/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/1326/5601/6283/5606/8737/8767/1849/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5608/4791/1846/3665/351/330/7098/79155/7867/64127/5602/3656/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/7316/7335/4205/4793/3146/7322/329/466/23291/6288/2002/6285/5609/1385/5599/148022 89 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-72613 Eukaryotic Translation Initiation 107/4699 119/10654 5.0038285701286817e-26 1.0181703351392275e-24 4.137414317329894e-25 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6192/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/8663/23521/8894/1981/6207/1977/6233/51386/6188/1978/200916/6122/1968/6230/8669/6194/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6181/8893/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/8891/51121/6217/6152/51065/6141/10480/1967/8661/9669/6209/11224/6165/6130/8890/6204/6228/6124/3646/6189/6135/6201/6161/8892/6133 107 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-72737 Cap-dependent Translation Initiation 107/4699 119/10654 5.0038285701286817e-26 1.0181703351392275e-24 4.137414317329894e-25 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6192/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/8663/23521/8894/1981/6207/1977/6233/51386/6188/1978/200916/6122/1968/6230/8669/6194/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6181/8893/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/8891/51121/6217/6152/51065/6141/10480/1967/8661/9669/6209/11224/6165/6130/8890/6204/6228/6124/3646/6189/6135/6201/6161/8892/6133 107 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 75/4699 76/10654 6.732336483577156e-26 1.350314346134618e-24 5.487107329471907e-25 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 75 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 82/4699 85/10654 8.5967185741938e-26 1.6533962846805611e-24 6.718704350703734e-25 8454/3725/9252/4790/1848/4792/177/1432/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/81793/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/246330/4615/7100/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 82 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 82/4699 85/10654 8.5967185741938e-26 1.6533962846805611e-24 6.718704350703734e-25 8454/3725/9252/4790/1848/4792/177/1432/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/81793/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/246330/4615/7100/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 82 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-975871 MyD88 cascade initiated on plasma membrane 82/4699 85/10654 8.5967185741938e-26 1.6533962846805611e-24 6.718704350703734e-25 8454/3725/9252/4790/1848/4792/177/1432/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/81793/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/246330/4615/7100/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 82 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 91/4699 97/10654 9.089420064023875e-26 1.7245332121472323e-24 7.0077747862033305e-25 8454/3725/9252/4790/1848/4792/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/6283/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/30849/5608/4791/1846/3665/351/8411/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/353376/57161/148022 91 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 74/4699 75/10654 1.5198680573113276e-25 2.845193003286805e-24 1.1561662976319154e-24 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 74 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-141424 Amplification of signal from the kinetochores 90/4699 96/10654 1.9544956237199375e-25 3.5637816307828464e-24 1.4481703732825785e-24 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/79902/3796/5519/81565/91687/11243/83540/7514/54820/6396/64946/9793/140735/220134/4928/5903/55055/80776/1783/401541/79172/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/55166/79003/5527/701/57551 90 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 90/4699 96/10654 1.9544956237199375e-25 3.5637816307828464e-24 1.4481703732825785e-24 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/79902/3796/5519/81565/91687/11243/83540/7514/54820/6396/64946/9793/140735/220134/4928/5903/55055/80776/1783/401541/79172/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/55166/79003/5527/701/57551 90 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-877300 Interferon gamma signaling 87/4699 92/10654 2.1945677497866673e-25 3.950221949616001e-24 1.6052034013284397e-24 80263/5777/960/5770/3107/817/9021/3383/55223/3662/3115/4684/567/6672/3113/3106/3459/3717/3117/11074/5371/3133/117854/3127/4938/4261/818/115362/7412/85363/9830/163351/2634/115361/10475/10437/10612/3458/3661/5580/81603/10107/4940/5781/3660/8554/3135/3665/3120/10379/2633/3123/23650/2209/8638/7706/23087/3122/3394/3663/6772/8651/3659/2635/5771/816/10346/3716/7726/79097/3105/3460/815/6737/23321/4281/3119/4502/51127/3664/4939/388646/7341/55128/3134/80128/5724 87 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 148/4699 182/10654 2.7521016924547862e-25 4.891076931906987e-24 1.987527138321778e-24 1912/23165/7068/7486/9112/6045/9212/80012/10274/348995/6613/57122/7181/23511/4929/28996/4792/3190/9759/9612/8856/1911/6790/6672/23279/1387/1789/23225/23512/165918/57332/7022/7067/7428/1107/5371/8924/4152/672/115426/9972/10499/6612/5914/8021/6117/11315/55746/7421/4286/10062/7150/6670/83746/3622/1788/51564/51588/3619/7153/51602/2516/8517/332/10762/5465/1655/5970/2099/79902/2494/9656/9883/84733/3066/7157/7158/10155/9063/7155/7690/6396/129401/7703/4791/6015/8554/7020/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/5111/4927/10521/1616/2908/8243/142/9971/1069/8086/7329/367/25942/648/6095/23468/5905/81929/5893/1487/55143/9631/5468/7021/8204/3090/79023/23636/10735/3183/53371/6996/9688/7341/2033/9126/3065/23314/6256/5987/7376/6294/8648/6304/8480/10891/7508/4193 148 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 113/4699 129/10654 4.000494874797054e-25 7.020868505268829e-24 2.8529845028157945e-24 8454/3725/9252/4790/7321/1848/1785/10333/4792/177/1432/929/3654/51135/6196/1759/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/1326/5601/6283/5606/8737/8767/5336/1849/29110/5594/4214/23118/841/8517/5528/7323/5970/7096/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/671/1846/3665/351/3684/330/51295/79155/8651/26052/7867/64127/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/7322/329/466/23291/114609/6288/2002/6285/5609/1385/5599/353376/7097/57161/3689/148022 113 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 89/4699 95/10654 4.199402434655187e-25 7.190196363726685e-24 2.921792194586793e-24 8454/3725/9252/4790/1848/10333/4792/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/1385/5599/7097/57161 89 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 89/4699 95/10654 4.199402434655187e-25 7.190196363726685e-24 2.921792194586793e-24 8454/3725/9252/4790/1848/10333/4792/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/1385/5599/7097/57161 89 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72/4699 73/10654 7.739245968144781e-25 1.3091447396717196e-23 5.3198114327640726e-24 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/5716/701/5693/5721 72 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2990846 SUMOylation 151/4699 188/10654 1.072423548290585e-24 1.7924793592856922e-23 7.283879237763123e-24 1912/10054/23165/7068/7486/9112/6045/9212/80012/10274/348995/6613/57122/7181/23511/4929/28996/4792/3190/9759/9612/8856/1911/6790/6672/23279/1387/1789/23225/10055/23512/165918/57332/7022/7067/7428/1107/5371/8924/4152/672/115426/9972/10499/6612/5914/8021/6117/11315/55746/7421/4286/10062/7150/6670/83746/3622/1788/51564/51588/3619/7153/51602/2516/8517/332/10762/5465/1655/5970/2099/79902/2494/9656/9883/84733/3066/7157/7158/10155/9063/7155/7690/6396/129401/7703/4791/6015/8554/7020/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/5111/4927/10521/1616/2908/8243/142/9971/1069/8086/7329/367/25942/648/6095/23468/5905/81929/5893/29843/1487/55143/9631/5468/7021/8204/3090/79023/23636/10735/3183/53371/6996/9688/7341/2033/9126/3065/23314/6256/5987/7376/6294/8648/6304/8480/10891/7508/4193 151 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8878166 Transcriptional regulation by RUNX2 107/4699 121/10654 1.29031962620204e-24 2.1313044178678403e-23 8.660721206210597e-24 8454/8493/5689/7291/5682/5925/143471/5705/5709/9978/5695/9759/10413/4089/3549/5711/650/5683/2101/5699/5702/5696/5691/7314/5718/25/6662/5700/122706/5707/5594/3280/23198/10013/2737/865/11059/983/6714/2099/9861/2932/6502/5698/10000/5692/5713/595/5710/5719/6233/7525/10432/4091/117581/1019/3958/5706/891/579/5714/6772/9464/2736/5688/5687/4322/2908/5708/208/5704/7311/367/860/5694/5595/57154/5684/8841/5720/23462/10273/207/5690/5717/9491/6500/4086/59269/10197/7316/10213/4094/1026/5715/5701/5685/5686/55294/23314/861/25925/5716/581/5693/5721/10891 107 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 71/4699 72/10654 1.7456099785619934e-24 2.785041374887544e-23 1.1317232157662685e-23 5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 71 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 71/4699 72/10654 1.7456099785619934e-24 2.785041374887544e-23 1.1317232157662685e-23 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 71 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 71/4699 72/10654 1.7456099785619934e-24 2.785041374887544e-23 1.1317232157662685e-23 5689/9134/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/990/5699/5702/8900/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/898/890/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/1017/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 71 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-162599 Late Phase of HIV Life Cycle 119/4699 139/10654 1.889193276457524e-24 2.980255460838611e-23 1.2110499773388269e-23 6884/23165/6875/27243/6874/348995/57122/5431/23511/5435/5433/2960/51271/23279/23327/29082/23225/2965/5439/6873/9972/6881/2967/51616/8021/11198/904/51497/55746/92421/7314/137492/25978/51160/2959/404672/10015/91782/5438/10762/79720/51534/4836/9397/79902/9883/83860/2068/5902/5478/6233/7514/1025/6396/129401/6883/7936/6829/2957/25920/4928/2963/5434/5903/55706/7175/5436/6878/4331/4927/8148/2966/2962/54457/8812/128866/905/2071/5901/8086/7311/93343/6880/6908/7251/1104/6882/2961/5432/22916/6877/5905/6917/81929/5440/902/9631/5430/6749/79023/5441/23636/7469/4686/7316/6872/53371/9688/8731/6879/9150/2958/5437/6827/2968/138474/1022/8178/8480 119 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69002 DNA Replication Pre-Initiation 81/4699 85/10654 2.2943178536915822e-24 3.579135851758868e-23 1.454409680351857e-23 5689/5682/143471/5705/5709/5422/1869/4174/5695/84515/4998/5711/10926/5683/990/5699/5702/55388/6117/5001/5696/5691/7314/5718/6118/23594/5700/122706/5707/23198/5557/9861/5698/5692/5713/4175/5710/5719/6233/23649/4999/4172/5000/8318/54107/4173/5706/5714/51053/6119/5688/5687/5427/5708/81620/1870/5704/23595/7311/5694/4176/56655/1017/5684/5720/8317/5690/5717/9491/10197/7316/10213/4171/1871/5715/5701/5685/5686/5716/5693/5721 81 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-68949 Orc1 removal from chromatin 70/4699 71/10654 3.936053692062913e-24 6.072768553468495e-23 2.4677167161342964e-23 8454/5689/5682/143471/5705/5709/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/890/9861/6502/5698/5692/5713/4175/5710/5719/6233/4999/4172/5000/4173/5706/5714/5688/5687/5708/81620/5704/23595/7311/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 70 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-72202 Transport of Mature Transcript to Cytoplasm 80/4699 84/10654 5.00560876418255e-24 7.63899424446989e-23 3.104164702731055e-23 23165/8683/6431/84271/199746/348995/57122/23511/81608/65109/23279/23225/9877/9972/8021/55746/7919/53981/6432/8563/6430/56001/80145/10762/22794/9785/11338/29107/4116/79902/9883/51213/10250/26097/51362/1977/57187/6396/129401/79228/2733/84324/4928/5903/55706/7175/7884/6428/10212/55110/84321/6429/4927/10898/10569/9295/10482/51692/8086/9939/6426/22916/10921/81929/9631/29894/79023/23636/4686/8189/53371/7307/9688/9984/10189/9775/84248/6427/8480/55339 80 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5663220 RHO GTPases Activate Formins 119/4699 140/10654 7.161183980791391e-24 1.081107775164636e-22 4.3931654981199023e-23 55839/11130/71/6249/9735/5526/51807/9212/347688/388/147841/348995/10381/57122/1780/23122/5048/57405/8655/23279/2491/7846/1060/81027/11004/1855/9184/5518/23332/25909/10726/81930/55746/5879/5515/79682/10403/25936/1856/389/3619/64105/332/5528/6714/79902/3796/5519/81565/91687/11243/10376/23002/83540/1857/7514/54820/6396/64946/9793/140735/220134/84617/4928/5903/55055/80776/1783/401541/10382/79172/7277/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/998/10383/5347/387/60/84790/84643/7280/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/6722/8379/23421/55920/79023/1781/4085/5216/81624/55166/51466/79003/5527/701/23380/57551 119 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 100/4699 112/10654 7.816279476027137e-24 1.1674528068449042e-22 4.744035247487916e-23 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/6202/6169/6175/6218/6192/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/8663/23521/8894/1981/6207/1977/6233/51386/6188/200916/6122/1968/6230/8669/6194/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6217/6152/51065/6141/10480/8661/9669/6209/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 100 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5607764 CLEC7A (Dectin-1) signaling 92/4699 101/10654 1.539643384867429e-23 2.275430855109337e-22 9.246390189453147e-23 8454/5689/4790/5682/7321/9039/29108/143471/5705/5530/5709/5695/4792/5711/5683/5699/5702/7334/3551/5696/5691/7314/257397/5718/8945/4773/5700/122706/5707/5336/23198/23118/10892/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/801/4791/5170/4772/4775/5706/6850/8915/5714/5688/5687/5708/7189/5704/7311/5971/5694/997/1147/5684/5720/6885/84433/5690/3553/5532/5717/9491/6500/10197/7316/10213/7335/10768/7322/5715/5701/23291/5685/5686/5534/5716/5693/5721 92 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 99/4699 111/10654 1.601137256981319e-23 2.341663238335179e-22 9.515530628112664e-23 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6192/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/8663/23521/8894/1981/6207/1977/6233/51386/6188/200916/6122/1968/6230/8669/6194/6136/6125/6232/6160/6193/6210/6229/6205/140801/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6217/6152/51065/6141/10480/8661/6209/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 99 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-68867 Assembly of the pre-replicative complex 67/4699 68/10654 4.503710523846032e-23 6.518772758226628e-22 2.648953992321812e-22 5689/5682/143471/5705/5709/1869/4174/5695/84515/4998/5711/5683/990/5699/5702/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/9861/5698/5692/5713/4175/5710/5719/6233/4999/4172/5000/4173/5706/5714/51053/5688/5687/5708/81620/1870/5704/23595/7311/5694/4176/5684/5720/5690/5717/9491/10197/7316/10213/4171/1871/5715/5701/5685/5686/5716/5693/5721 67 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 80/4699 85/10654 4.838626333203874e-23 6.932072828385959e-22 2.8169016891476905e-22 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/91768/5934/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/1163/1019/5706/286826/4331/5714/5688/5687/5708/1874/208/5704/55957/51343/7311/5694/1017/5684/994/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1026/5715/5701/5685/5686/5716/1022/5693/5721 80 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-446652 Interleukin-1 family signaling 118/4699 140/10654 5.061893434824176e-23 7.178685234841559e-22 2.91711455786784e-22 8454/834/5689/5777/4790/5682/1511/26469/5783/8878/143471/5705/5709/9978/5695/4792/3606/177/5711/4088/5683/84867/5699/5702/3654/51135/7334/3551/5696/5691/7314/3596/257397/5718/8945/1326/6283/90865/5700/122706/5707/8767/29110/23198/23118/8517/3565/5970/8809/9861/5698/5692/5713/5710/10454/5719/6233/7850/5781/5608/4791/3557/351/5782/54472/5706/79155/6774/5780/5714/64127/3552/5688/5687/5708/3656/57162/5771/7189/5704/7311/5694/6416/3554/1147/5778/5684/5720/6885/5604/4215/10392/5690/3553/5717/9491/6500/25930/246330/10197/4615/7316/10213/7335/4793/3146/5715/5701/23291/5685/5686/6288/6285/5716/5599/57161/5693/5721 118 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1169091 Activation of NF-kappaB in B cells 66/4699 67/10654 1.0141947277001388e-22 1.4098310868227673e-21 5.728958232553157e-22 8454/5689/4790/5579/5682/143471/5705/5709/5695/4792/5711/5683/5699/5702/4794/3551/5696/5691/7314/5718/8945/5966/5700/122706/5707/23198/10892/8517/5970/9861/5698/5692/5713/5710/5719/6233/5706/8915/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/84433/5690/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5716/5693/5721 66 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 66/4699 67/10654 1.0141947277001388e-22 1.4098310868227673e-21 5.728958232553157e-22 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 66 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 96/4699 108/10654 1.3664581078404805e-22 1.8808893954980733e-21 7.64314029359691e-22 5295/3605/7124/2308/1052/7291/356/3593/9021/3082/5743/3091/10538/3383/6097/6657/3576/3662/4985/7133/3606/4609/4988/3717/6347/7040/3312/3569/4692/3596/3598/3592/7412/4582/6367/4312/6778/332/4313/3565/3976/5443/3718/149233/598/2247/2335/595/7157/2353/604/7076/51561/3570/7297/9655/3566/7184/3684/4318/3726/301/6774/6772/8651/1901/3552/79923/112744/3716/6356/5008/3586/6095/596/2208/2309/3561/207/5292/5451/7422/3553/2625/3597/4314/1026/3320/4843/6288/6935/3687/7431/3162/4170/3689 96 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 89/4699 98/10654 1.3972128961664244e-22 1.886237409824673e-21 7.664872365609333e-22 8454/3725/9252/4790/1848/10333/4792/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/1385/5599/7097/57161 89 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 89/4699 98/10654 1.3972128961664244e-22 1.886237409824673e-21 7.664872365609333e-22 8454/3725/9252/4790/1848/10333/4792/177/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/6283/5606/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/1385/5599/7097/57161 89 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5696398 Nucleotide Excision Repair 98/4699 111/10654 1.5901850784627128e-22 2.1263046192015703e-21 8.640404135606922e-22 2074/10445/5982/6613/7507/5431/5435/9978/5433/10980/2965/5439/10987/2067/2967/6612/6117/7334/10714/91603/7314/6118/83444/404672/86/5438/3978/1643/29844/5985/10920/2068/5984/54891/6233/93973/8607/7874/5424/5886/8451/8554/10450/5434/5436/7515/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/142/2071/1069/7329/51426/2873/7311/3980/60/8533/5983/5432/51138/7528/56655/9318/6917/5440/902/27339/5430/5441/7336/54778/7316/64708/283899/7341/4798/5437/79913/54617/2033/2968/56949/5887/9716/5981/1022/8178/50813/7508 98 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69202 Cyclin E associated events during G1/S transition 78/4699 83/10654 2.244424044178039e-22 2.972803167949025e-21 1.2080216801832146e-21 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/91768/5934/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/1163/1019/5706/286826/4331/5714/5688/5687/5708/1874/208/5704/55957/7311/5694/1017/5684/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1026/5715/5701/5685/5686/5716/1022/5693/5721 78 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2871837 FCERI mediated NF-kB activation 77/4699 82/10654 4.82763906270366e-22 6.334584340220504e-21 2.5741075966408107e-21 8454/5689/4790/5682/7321/143471/5705/5709/5695/4792/5711/5683/5699/5702/7334/3551/5696/5691/7314/257397/5718/8945/5700/122706/5707/23198/23118/10892/8517/5970/9861/5588/5698/5692/5713/5710/10454/5719/6233/5170/2205/5706/2206/8915/5714/5688/5687/4067/5708/7189/5704/7311/5694/997/1147/5684/5720/6885/84433/5690/5717/9491/6500/10197/7316/10213/7335/7322/5715/5701/23291/5685/5686/5716/5693/5721/2207 77 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6807505 RNA polymerase II transcribes snRNA genes 71/4699 74/10654 5.084826435776729e-22 6.6102743665097474e-21 2.6861363822524242e-21 6884/51585/5431/5435/23379/5433/2960/55656/5439/10302/904/65123/55197/2959/79871/5438/6667/29101/79664/25896/23248/1025/7702/6829/2957/2963/5434/26173/5436/26512/6878/55756/58490/2962/51808/8812/129685/905/5452/64859/22936/6621/6880/6908/80237/6619/6882/2961/5432/22916/6618/6877/5440/57508/5430/5451/55174/6617/5441/84524/4686/2958/5437/92105/6827/80789/57117/51593/79035/1022/8178 71 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-927802 Nonsense-Mediated Decay (NMD) 100/4699 115/10654 7.79275431451676e-22 9.946388234165027e-21 4.041792189921612e-21 6158/9887/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/65109/6192/6156/6143/5520/6139/23381/5518/3921/6208/6170/5515/6203/6147/6222/26019/2935/6134/22794/6155/4116/6231/6142/23521/1981/6207/6233/6188/5976/200916/6122/6230/6194/2107/56006/6136/6125/6232/6160/55110/6193/6210/6229/6205/140801/6181/9939/7311/6223/25873/9045/6187/65110/6168/22916/6157/6137/10921/6144/9349/4736/51121/6217/6152/51065/6141/4686/6209/11224/6165/6130/6204/6228/55802/6124/6189/9775/6135/6201/6161/6133 100 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 100/4699 115/10654 7.79275431451676e-22 9.946388234165027e-21 4.041792189921612e-21 6158/9887/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/65109/6192/6156/6143/5520/6139/23381/5518/3921/6208/6170/5515/6203/6147/6222/26019/2935/6134/22794/6155/4116/6231/6142/23521/1981/6207/6233/6188/5976/200916/6122/6230/6194/2107/56006/6136/6125/6232/6160/55110/6193/6210/6229/6205/140801/6181/9939/7311/6223/25873/9045/6187/65110/6168/22916/6157/6137/10921/6144/9349/4736/51121/6217/6152/51065/6141/4686/6209/11224/6165/6130/6204/6228/55802/6124/6189/9775/6135/6201/6161/6133 100 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-909733 Interferon alpha/beta signaling 67/4699 69/10654 8.84019090719811e-22 1.1181646877212745e-20 4.543749143386795e-21 3443/5777/5770/3107/9021/11274/3662/3106/4599/684/3133/3429/91543/4938/5696/3445/10410/9636/2634/3444/103/3434/3433/3451/3448/3661/3439/10581/3452/4940/3437/6773/7297/5781/3430/3660/3446/3135/3665/10379/3455/4600/8638/3394/3663/6772/8651/3659/25939/3440/3454/3716/3456/3105/3441/51447/54739/2537/3449/8519/3664/6041/1958/4939/6059/3669/3134 67 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-450294 MAP kinase activation 63/4699 64/10654 1.1557905999739963e-21 1.4488660735388313e-20 5.887579935957763e-21 8454/3725/9252/4790/1848/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/23118/8517/5528/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/1846/79155/7867/64127/5602/3656/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/7316/7335/4205/466/23291/2002/5609/1385/5599 63 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69615 G1/S DNA Damage Checkpoints 66/4699 68/10654 1.9620376013113093e-21 2.4377883117177685e-20 9.90614233731467e-21 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/993/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/1111/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 66 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-72689 Formation of a pool of free 40S subunits 90/4699 101/10654 1.9901450189678367e-21 2.4510207075709146e-20 9.95991320665344e-21 6158/6138/6227/6206/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/6202/6169/6175/6218/6192/6156/6143/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/8663/23521/6207/6233/51386/6188/200916/6122/6230/8669/6194/6136/6125/6232/6160/6193/6210/6229/6205/140801/6181/7311/6223/25873/8664/9045/6187/6168/6157/6137/6144/9349/4736/51121/6217/6152/51065/6141/10480/8661/6209/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 90 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 62/4699 63/10654 2.599103582090115e-21 3.1731664602213233e-20 1.2894408617783457e-20 5689/11065/5682/7321/8697/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/5707/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 62 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 77/4699 83/10654 3.797889846711666e-21 4.5574678160539994e-20 1.8519624803578258e-20 8454/5689/4893/4790/5579/5682/143471/5705/5530/5709/5695/4792/5711/5683/5699/5702/4794/3845/3265/3551/5696/5691/7314/5718/8945/4773/5966/5700/122706/5707/23198/10892/8517/5970/9861/5698/5692/5713/5710/5478/5719/6233/801/4772/4775/5706/8915/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/84433/5690/5532/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5534/5716/5693/5721 77 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1236974 ER-Phagosome pathway 77/4699 83/10654 3.797889846711666e-21 4.5574678160539994e-20 1.8519624803578258e-20 8773/5689/5682/3107/811/143471/5705/10333/5709/5695/567/3106/5711/5683/929/5699/5702/3133/3551/5696/5691/7314/5718/10952/5700/122706/5707/23198/6892/8517/7096/9861/5698/5692/5713/5710/5719/6233/3135/6890/5706/29927/5714/5688/5687/5708/2923/695/5704/7311/5694/8673/3105/23643/1147/5684/5720/5690/5717/9491/10197/7099/4615/6891/7316/10213/5715/5701/9341/5685/5686/114609/5716/3134/7097/5693/5721 77 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-73856 RNA Polymerase II Transcription Termination 65/4699 67/10654 4.352253337005376e-21 5.178443800979278e-20 2.1043008997831524e-20 8683/6431/84271/51585/199746/81608/1477/65109/9877/7919/53981/6432/8563/6430/134353/11051/80145/8106/22794/9785/11338/4116/1478/51213/10250/26097/51362/23283/6636/10914/57187/79228/84324/6635/7884/6428/10212/84967/6637/55110/84321/6429/10898/10569/9295/51692/9939/6426/22916/1479/10921/79869/29894/4686/8189/10978/7307/9984/10189/6634/9775/84248/6427/55339/6628 65 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1234174 Cellular response to hypoxia 71/4699 75/10654 5.423372379576178e-21 6.345345684104127e-20 2.5784805523949902e-20 5689/5682/64344/7321/3091/143471/5705/5709/9978/5695/5711/1387/5683/5699/126374/25994/7428/5702/2056/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/405/768/112399/84962/5706/5714/10370/5688/5687/5708/5704/7311/2034/55662/5694/5684/5720/7422/5690/5717/9491/10197/7316/10213/8994/7322/5715/5701/5685/5686/2033/8453/5716/54583/5693/5721 71 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 71/4699 75/10654 5.423372379576178e-21 6.345345684104127e-20 2.5784805523949902e-20 23165/8683/6431/84271/199746/348995/57122/23511/65109/23279/23225/9877/9972/8021/55746/7919/6432/8563/6430/56001/80145/10762/22794/9785/11338/29107/4116/79902/9883/51213/10250/26097/51362/57187/6396/129401/79228/2733/84324/4928/5903/55706/7175/6428/10212/55110/84321/6429/4927/10569/9295/10482/8086/9939/6426/22916/10921/81929/9631/79023/23636/4686/53371/7307/9688/9984/10189/9775/84248/6427/8480 71 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-3371556 Cellular response to heat stress 81/4699 89/10654 8.365737707409853e-21 9.707021273721846e-20 3.9445235645203486e-20 23165/6782/573/7531/1915/817/9530/348995/472/57122/3313/23511/3305/23279/1387/259217/23225/3309/2475/3306/9972/23411/8021/6117/3312/55746/51182/818/3303/6118/5594/3308/84335/10049/10013/3337/10762/9261/79902/9883/2932/6396/129401/3297/57521/4928/5903/55706/7175/1410/4927/64223/6119/26353/57805/3310/7266/816/8086/3326/3304/10728/5595/815/81929/9631/116835/545/79023/23636/10808/53371/9532/9688/7415/3320/2033/22824/9529/2288/8480 81 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 90/4699 102/10654 9.61746600012201e-21 1.0925014837806417e-19 4.439464718916688e-20 8454/8792/7124/5689/5682/356/9039/143471/5705/10673/5709/5695/3604/7292/7133/5711/5683/5699/5702/60401/8740/944/7187/51330/958/5696/5691/939/7314/5718/8945/5700/122706/5707/23198/9020/8741/9861/5698/5692/5713/5710/8718/9040/5719/6233/8742/4791/959/4055/8600/330/5706/5714/5688/5687/5708/5704/7311/5971/115650/5694/8771/1147/4050/5684/5720/7186/5690/5717/9491/6500/10197/7316/10213/970/5715/7132/5701/329/23291/5685/5686/128178/4049/5716/7293/8784/5693/5721 90 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69563 p53-Dependent G1 DNA Damage Response 64/4699 66/10654 9.648873503475753e-21 1.0925014837806417e-19 4.439464718916688e-20 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 64/4699 66/10654 9.648873503475753e-21 1.0925014837806417e-19 4.439464718916688e-20 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-674695 RNA Polymerase II Pre-transcription Events 77/4699 84/10654 2.5919054086260215e-20 2.911228154968747e-19 1.1830001949265716e-19 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/11198/904/51497/4300/80349/2959/404672/5438/83860/2068/1025/23168/55677/6883/7936/6829/2957/123169/25920/85403/2963/5434/5436/9646/6878/79577/4331/8148/2966/2962/4298/54457/8812/905/2071/27125/6880/6908/6882/2961/5432/22916/55840/6877/6917/5440/902/6830/5430/6749/5441/7469/4686/6872/6879/9150/54623/2958/5437/6827/2968/138474/1022/8178 77 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 59/4699 60/10654 2.9490812509665604e-20 3.1850077510438854e-19 1.294252662367511e-19 8454/5689/9134/5682/5705/5709/5753/5695/5711/5683/5699/5702/8900/5696/5691/7314/5718/5700/5707/898/890/9861/6502/5698/5692/5713/595/5710/5719/6233/1163/1019/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/5690/5717/1027/9491/6500/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721 59 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 59/4699 60/10654 2.9490812509665604e-20 3.1850077510438854e-19 1.294252662367511e-19 8454/5689/5682/9039/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/5970/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 59 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5610780 Degradation of GLI1 by the proteasome 59/4699 60/10654 2.9490812509665604e-20 3.1850077510438854e-19 1.294252662367511e-19 8454/5689/5682/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/83737/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/8650/9861/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/2735/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5610783 Degradation of GLI2 by the proteasome 59/4699 60/10654 2.9490812509665604e-20 3.1850077510438854e-19 1.294252662367511e-19 8454/5689/5682/1452/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/9861/2932/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/2736/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 59/4699 60/10654 2.9490812509665604e-20 3.1850077510438854e-19 1.294252662367511e-19 8454/5689/5682/1452/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/2737/9861/2932/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 74/4699 80/10654 3.6238401286932486e-20 3.8838714051032988e-19 1.5782413417048942e-19 3839/23165/201626/5335/348995/57122/11274/23511/4734/23279/23225/1973/3836/4599/9972/8021/7334/4938/55746/7314/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/1977/51191/6233/5610/4940/6396/129401/4928/3838/5903/55706/7175/2316/4600/8638/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/7318/1974/5595/3837/81929/9631/79023/23636/7316/53371/9688/6041/4939/6059/5300/9775/5495/8480 74 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-3858494 Beta-catenin independent WNT signaling 118/4699 146/10654 5.500661643196523e-20 5.850703747763575e-19 2.3774789558313527e-19 2788/5689/5579/5682/5578/1212/5582/27327/143471/5705/2775/5530/5709/5695/5711/5683/5699/2782/5702/192669/1855/163/4343/3845/5696/5691/4920/7314/5879/2787/5718/2535/161/51701/5700/122706/5707/1856/8322/23198/10681/7471/2792/9861/8321/5698/5692/5713/2785/2783/23002/2784/5710/5719/6233/7474/1857/1213/1211/7855/1175/26523/801/2791/1173/144165/4772/409/5706/160/5714/6934/5688/5687/4919/5708/2786/5704/7311/387/5694/57154/27161/815/5684/5720/54331/6885/1499/59345/5690/5532/57690/5717/9491/51764/94235/10197/192670/64750/7316/10213/55970/5216/5715/5701/2793/5685/5686/5534/23112/23513/5716/5693/5721/6259/2790/5592 118 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-156842 Eukaryotic Translation Elongation 83/4699 93/10654 5.899779645820392e-20 6.228038062204383e-19 2.530811688195214e-19 6158/6138/6227/6206/6234/6191/6128/6132/1917/6129/1915/6176/6224/6146/6154/6202/6169/6175/6218/6192/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/1938/6136/6125/1937/6232/6160/1933/6193/6210/6229/6205/140801/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6217/1936/6152/51065/6141/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 83 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5676590 NIK-->noncanonical NF-kB signaling 58/4699 59/10654 6.621745228973462e-20 6.8866150381324e-19 2.798429562653892e-19 8454/5689/5682/9039/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 58 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 58/4699 59/10654 6.621745228973462e-20 6.8866150381324e-19 2.798429562653892e-19 5689/5682/143471/5705/5709/5695/84515/4998/5711/5683/990/5699/5702/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/4999/5000/5706/5714/51053/5688/5687/5708/81620/5704/23595/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 58 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1236975 Antigen processing-Cross presentation 87/4699 99/10654 7.921386167464758e-20 8.177666308176854e-19 3.323058283874535e-19 8773/5689/5682/3107/811/143471/5705/10333/5709/5695/567/3106/5711/5683/929/5699/5702/3133/3551/5696/5691/7314/5718/10952/5700/122706/5707/23198/6892/8517/1515/7096/9861/5698/5692/5713/5710/5719/6233/3685/1535/1514/3135/653361/6890/2209/5706/29927/50489/5714/5688/5687/5708/2923/695/5704/4012/7311/5694/8673/3105/23643/1147/5684/5720/5690/5717/9491/10197/7099/4615/6891/7316/10213/5715/5701/9341/5685/5686/114609/1520/5716/3134/7097/5693/5721/4360 87 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6802957 Oncogenic MAPK signaling 67/4699 71/10654 1.1853773446076542e-19 1.2147954684884282e-18 4.936415833863609e-19 4893/71/817/5908/55109/54845/8546/22866/5605/5037/3717/10827/2244/3690/408/4296/5894/8826/1185/4140/3845/3265/4763/818/8805/55750/8844/7094/5594/7414/10533/23164/57085/6714/9061/2335/1445/2266/2243/369/801/57670/283455/3674/409/673/816/56829/7450/60/9444/7529/5595/4000/27044/815/22906/8087/5604/10018/10142/54518/80853/10256/5906/9715/5245 67 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6802952 Signaling by BRAF and RAF fusions 64/4699 67/10654 1.2264343705484407e-19 1.2477636639492833e-18 5.070384659323073e-19 4893/71/817/5908/55109/54845/8546/22866/5605/5037/3717/10827/2244/3690/408/5894/8826/1185/4140/3845/3265/818/8805/55750/8844/7094/5594/7414/10533/23164/57085/6714/9061/2335/1445/2266/2243/369/801/57670/283455/3674/409/673/816/56829/7450/60/9444/7529/5595/4000/27044/815/22906/8087/5604/10018/10142/54518/80853/10256/5906/9715 64 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 84/4699 95/10654 1.415398122756959e-19 1.4296539311876044e-18 5.809509901811979e-19 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/6192/6156/6143/6139/3921/6208/6170/6203/6147/6222/2935/6134/6155/6231/6142/23521/1981/6207/6233/6188/5976/200916/6122/6230/6194/2107/6136/6125/6232/6160/6193/6210/6229/6205/140801/6181/7311/6223/25873/9045/6187/6168/22916/6157/6137/6144/9349/4736/51121/6217/6152/51065/6141/4686/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 84 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-72187 mRNA 3'-end processing 57/4699 58/10654 1.486223457505106e-19 1.4904698102408348e-18 6.056639954644868e-19 8683/6431/84271/51585/199746/81608/1477/65109/9877/7919/53981/6432/8563/6430/11051/80145/8106/22794/9785/11338/4116/1478/51213/10250/26097/51362/23283/10914/57187/79228/84324/6428/10212/55110/84321/6429/10898/10569/9295/51692/9939/6426/22916/1479/10921/79869/29894/4686/8189/10978/7307/9984/10189/9775/84248/6427/55339 57 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 71/4699 77/10654 3.423735891104614e-19 3.4091668022062966e-18 1.3853414355944013e-18 5689/5682/51807/63943/347688/143471/10381/5705/5709/5695/5711/7846/5683/5699/5702/81027/5696/5691/7314/5718/5700/122706/5707/23198/983/9861/5698/5692/5713/10376/5710/7157/5719/6233/84617/51512/10382/7277/5706/9133/891/5714/5688/5687/5708/22919/5704/3326/7311/10383/5347/84790/5694/7280/5684/5720/5690/5717/9491/10197/7316/10213/1026/5715/5701/5685/3320/5686/5716/5693/5721 71 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8939902 Regulation of RUNX2 expression and activity 68/4699 73/10654 4.560440864934037e-19 4.509055615751681e-18 1.8322898063708288e-18 8454/5689/7291/5682/143471/5705/5709/9978/5695/5711/650/5683/2101/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/865/11059/2099/9861/2932/6502/5698/5692/5713/5710/5719/6233/5706/579/5714/6772/5688/5687/2908/5708/5704/7311/860/5694/57154/5684/5720/10273/5690/5717/9491/6500/59269/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721/10891 68 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8878159 Transcriptional regulation by RUNX3 84/4699 96/10654 6.438705300343474e-19 6.3216379312463204e-18 2.568846722698685e-18 5689/5682/5705/6097/6696/5709/5695/9759/10413/4609/4089/22938/5711/1387/4088/5683/5699/5702/9794/7040/3845/5696/5691/7314/5718/8463/2648/5700/5707/55534/3280/84441/3683/865/6714/9861/8850/5698/5692/5713/595/5710/7157/5719/6233/1029/864/5706/10046/5714/6934/5688/5687/5708/5704/7311/5694/4851/3676/57154/5684/5720/2309/1499/10018/5690/5717/9491/10197/64750/7316/10213/1026/5715/5701/5685/5686/2033/861/5716/3516/5693/5721/4193 84 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6798695 Neutrophil degranulation 306/4699 480/10654 6.71496526653477e-19 6.547091134871401e-18 2.6604613848405306e-18 5869/8773/7130/9798/1727/5689/8804/5777/5806/4893/9218/4790/3240/960/7305/1511/5657/1915/3107/203068/5175/383/8836/2268/5211/5908/1460/29108/23385/54509/6280/5788/535/10577/5709/10576/1509/5695/2896/4126/8655/567/290/7133/154664/3106/3074/3417/3043/388698/2548/1432/11010/3920/5476/8904/5683/929/201294/158747/2588/3482/4311/80142/2444/23200/5702/566/9961/51552/10075/56729/10487/684/6709/6093/8826/9522/4282/3608/2720/3312/3071/387263/2665/1654/967/2519/6037/5879/51316/2717/1992/5718/3303/58485/2934/80331/64333/56954/161/6283/56888/3579/5707/2358/3848/823/353189/5594/4680/6727/127829/7414/10533/55754/4257/326624/847/3683/2517/25852/22918/8895/5834/9545/1315/4069/965/9861/5870/410/411/28988/978/55832/968/5713/2495/3614/3728/10043/4125/5478/5719/374395/728/5580/23191/3685/302/9145/25797/6036/1535/2040/230/317/2990/401258/5663/7879/8907/671/2992/1508/28956/10450/25801/1828/23352/23412/7276/5284/4332/10159/1938/8635/51646/1650/3684/79888/387921/3163/64386/54472/3577/2215/55860/2760/5864/4318/3958/79980/23317/6993/11240/5611/84061/1116/527/6279/54918/210/10092/5795/6793/197/2171/3310/1832/5708/55313/3615/820/51143/4860/6386/10788/6402/5473/3326/10857/55004/10097/3916/10383/387/178/10396/683/51806/80184/3304/2547/8673/10493/1075/114790/1778/10694/2512/3837/5036/8621/5005/29099/11333/5315/8876/23197/1991/10120/6317/7520/5717/2919/5004/1512/2357/10213/4718/6278/5547/2799/9588/29952/7415/3146/4353/5701/9342/6836/8649/5265/3320/5686/388697/23593/175/25798/5873/1088/150372/26578/5878/2683/8566/11031/1520/719/93100/47/5906/81567/3687/353376/7097/5660/10970/3689/2207/5724/51382/2950/718 306 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 55/4699 56/10654 7.477704776119946e-19 7.240481038394761e-18 2.942225763090389e-18 5689/5682/26986/143471/5705/5709/5695/5711/5683/5699/5702/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/9861/5698/5692/5713/1981/5710/5719/6233/3315/5706/5714/5688/5687/5708/5704/7311/5694/3304/5684/5720/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 55 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 302/4699 473/10654 8.313285899970625e-19 7.994420139423807e-18 3.2485947785033018e-18 5295/374/5777/627/3643/9252/4893/857/2250/5335/71/5579/5770/5291/26469/1848/5578/1785/5908/3082/51741/23385/2064/535/54845/5431/6696/6776/5435/5433/5753/5327/4734/10413/5605/3910/8569/1432/3717/55824/2534/9475/3690/9965/5439/2264/5603/3630/6456/83737/6868/7072/4145/9542/30011/2885/2475/8660/6093/163/7073/6196/9846/1759/5518/8440/2252/8874/6197/3845/3265/1399/3071/8877/5062/4486/51231/5829/7314/5879/5515/6387/5607/54106/26999/51606/161/5290/3667/4485/8823/2065/3815/5567/8027/10006/537/1849/2060/5594/8074/23118/57761/5921/6778/2260/5438/348/5528/9306/1500/3185/11059/9261/2249/6714/2099/2248/5519/5598/4208/4670/2567/2247/4914/10810/10000/9146/6455/2335/64759/6195/3728/8471/1445/3925/6233/7525/5580/7409/2246/23191/3685/2251/3932/1213/3791/1211/29924/1535/5600/6777/1175/6300/801/200734/5781/30849/5663/5725/10787/1846/253260/25920/5170/1173/2963/5434/5800/5590/6464/85440/653361/5241/2904/5747/5782/135/5436/10019/10193/5568/7074/3315/4318/382/160/673/527/6774/2263/4233/10152/6772/8651/26052/7867/64223/5566/2962/1003/8503/5795/10163/5159/4067/3084/55845/5063/5771/1111/998/3481/208/6654/5867/10718/79109/7006/5900/7311/2185/387/53834/1956/60/10750/2549/5058/1020/5432/3480/22916/11140/7529/5595/5516/1845/10253/9402/5440/8065/558/4915/1495/5604/1499/4690/5430/10048/10273/207/7422/10458/3178/8817/5441/58513/2254/4686/7316/152831/1950/9611/9047/4205/10768/26281/10818/1281/8936/23545/2261/867/5437/466/2255/3320/4846/4803/2002/2066/27006/6285/1398/3187/1385/5906/3479/8851/5296/5581/581/10076/7059/7057/10254/6457/51382/5156/161742/2887 302 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-448424 Interleukin-17 signaling 67/4699 72/10654 9.713356508560784e-19 9.277246624502954e-18 3.7698812944074076e-18 8454/3605/3725/9252/4790/1848/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/23118/8517/5528/84818/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/1846/79155/7867/64127/5602/3656/7189/112744/7311/23765/6416/5595/5516/1147/1845/6885/5604/10392/6500/7316/7335/4205/466/23291/2002/5609/1385/5599 67 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-156902 Peptide chain elongation 79/4699 89/10654 1.0213510075778884e-18 9.689032531346995e-18 3.9372136991978345e-18 6158/6138/6227/6206/6234/6191/6128/6132/6129/1915/6176/6224/6146/6154/6202/6169/6175/6218/6192/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/1938/6136/6125/6232/6160/6193/6210/6229/6205/140801/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6217/6152/51065/6141/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 79 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 54/4699 55/10654 1.6762233929359442e-18 1.5585547309152753e-17 6.333308323257455e-18 8454/5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/26271/5706/5714/5688/5687/5708/5704/51343/7311/5694/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 54 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-4641257 Degradation of AXIN 54/4699 55/10654 1.6762233929359442e-18 1.5585547309152753e-17 6.333308323257455e-18 5689/5682/143471/5705/5709/5695/5711/5683/5699/8312/5702/80351/5696/5691/7314/5718/5700/122706/5707/23198/9861/81847/5698/5692/5713/5710/8313/5719/6233/5706/8658/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/5716/5693/5721 54 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8941858 Regulation of RUNX3 expression and activity 54/4699 55/10654 1.6762233929359442e-18 1.5585547309152753e-17 6.333308323257455e-18 5689/5682/5705/5709/5695/5711/5683/5699/5702/7040/5696/5691/7314/5718/5700/5707/865/6714/9861/5698/5692/5713/5710/5719/6233/1029/864/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/2033/5716/5693/5721/4193 54 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5621481 C-type lectin receptors (CLRs) 113/4699 142/10654 3.3242596707416766e-18 3.070566169553496e-17 1.2477484359709064e-17 8454/5689/4586/9252/4893/4790/5682/7321/9039/29108/143471/5705/5530/5709/5695/4792/5711/1387/5683/2534/5699/3385/5702/5894/3845/7334/3265/3551/5062/5696/5691/7314/257397/5718/8945/4773/5700/122706/5707/5567/5336/4582/23198/23118/10892/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/801/4791/5170/4772/5568/4775/3384/5706/6850/8915/5714/5566/5688/5687/4067/5708/5063/7189/5704/30835/7311/5971/5694/5058/997/1147/5684/5720/6885/84433/5690/3553/5532/5717/9491/6500/10197/7316/10213/7335/10768/7322/5715/5701/23291/5685/5686/2033/5534/5716/5693/5721/2207 113 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 75/4699 84/10654 3.570367007124312e-18 3.276336783008192e-17 1.331364924569231e-17 10445/5982/6613/7507/9978/10980/2965/10987/2067/2967/6612/6117/7334/10714/7314/6118/83444/404672/86/3978/1643/29844/5985/10920/2068/5984/54891/6233/93973/8607/5424/5886/8451/8554/7515/54107/8450/4331/5425/5111/2966/6119/5427/1642/142/2071/1069/7329/51426/2873/7311/3980/60/8533/5983/51138/7528/56655/9318/902/7336/54778/7316/64708/283899/7341/4798/79913/54617/2968/5887/5981/1022/50813/7508 75 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 53/4699 54/10654 3.755808225534876e-18 3.424126460162965e-17 1.391420408913126e-17 8454/5689/5682/143471/5705/5709/9978/5695/6790/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/23194/5693/5721 53 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 62/4699 66/10654 5.484876650103575e-18 4.968236655964787e-17 2.0188815920924537e-17 5689/5682/64344/7321/3091/143471/5705/5709/9978/5695/5711/5683/5699/126374/7428/5702/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/112399/84962/5706/5714/5688/5687/5708/5704/7311/2034/5694/5684/5720/5690/5717/9491/10197/7316/10213/8994/7322/5715/5701/5685/5686/8453/5716/54583/5693/5721 62 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5610787 Hedgehog 'off' state 94/4699 113/10654 8.34466844561952e-18 7.510201601057568e-17 3.0518288107461404e-17 8454/5689/5682/1452/51684/143471/10381/5705/5709/9978/5695/107/5711/7846/5683/5699/5702/81027/83737/5696/5691/7314/5718/8945/5700/122706/5707/5567/27152/23198/112/5573/2737/5727/8650/111/9861/2932/5698/5692/5713/10376/5710/5719/6233/23322/196883/115/84617/54903/10382/5568/7277/5706/113/5714/5566/2736/5688/5687/5708/5577/5704/7311/10383/84790/5694/7280/109/5684/5720/2735/5575/6608/5690/5717/9491/6500/114/7289/10197/108/7316/10213/2778/5715/5701/5576/5685/5686/5716/8481/5693/5721 94 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8948751 Regulation of PTEN stability and activity 64/4699 69/10654 9.32172762586357e-18 8.336118208097104e-17 3.387446445335605e-17 5689/5682/1459/1460/143471/5705/5709/5695/1457/4734/5711/5683/5699/2444/5702/80351/5696/5691/7314/5718/5700/122706/5707/23198/9861/81847/5698/10000/5692/5713/5710/5719/6233/331/23608/5706/8658/5714/5688/5687/5708/208/5704/7311/5694/5684/5720/10273/207/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5728/5987/5716/5693/5721 64 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-192823 Viral mRNA Translation 78/4699 89/10654 9.552306278932535e-18 8.488251908621062e-17 3.44926715734939e-17 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6192/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/6136/6125/6232/6160/5611/6193/6210/6229/6205/140801/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6217/6152/51065/6141/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 78 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-4086400 PCP/CE pathway 80/4699 92/10654 1.0293991183203567e-17 9.089788441017491e-17 3.693706204102174e-17 5689/5579/5682/5578/1212/5582/143471/5705/5709/5695/5711/5683/5699/5702/1855/163/5696/5691/4920/7314/5879/5718/2535/161/5700/122706/5707/1856/8322/23198/7471/9861/8321/5698/5692/5713/23002/5710/5719/6233/7474/1857/1213/1211/7855/1175/1173/144165/409/5706/160/5714/5688/5687/4919/5708/5704/7311/387/5694/57154/5684/5720/5690/5717/9491/10197/64750/7316/10213/5216/5715/5701/5685/5686/23513/5716/5693/5721/6259 80 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-4641258 Degradation of DVL 55/4699 57/10654 1.2141862397505685e-17 1.0568811813059786e-16 4.2947188504111595e-17 5689/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/1855/5696/5691/7314/5718/5700/122706/5707/1856/23198/59349/9861/5698/5692/5713/5710/5719/6233/1857/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/23072/5693/5721 55 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69541 Stabilization of p53 55/4699 57/10654 1.2141862397505685e-17 1.0568811813059786e-16 4.2947188504111595e-17 5689/5682/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/51230/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721/4193 55 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 71/4699 79/10654 1.2194782861222831e-17 1.0568811813059786e-16 4.2947188504111595e-17 2074/5982/7507/5431/5435/9978/5433/10980/2965/5439/10987/2067/2967/6117/10714/91603/7314/6118/404672/5438/3978/5985/10920/2068/5984/6233/7874/5424/8451/10450/5434/5436/7515/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/2071/51426/2873/7311/3980/8533/5983/5432/51138/56655/9318/6917/5440/902/27339/5430/5441/7316/64708/5437/2033/2968/56949/9716/5981/1022/8178/50813 71 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1169408 ISG15 antiviral mechanism 66/4699 72/10654 1.4113958407304505e-17 1.215705374469664e-16 4.940113307561538e-17 3839/23165/5335/348995/57122/11274/23511/4734/23279/23225/1973/3836/4599/9972/8021/7334/55746/7314/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/1977/51191/6233/5610/6396/129401/4928/3838/5903/55706/7175/4600/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/7318/1974/5595/3837/81929/9631/79023/23636/7316/53371/9688/5300/9775/5495/8480 66 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-195253 Degradation of beta-catenin by the destruction complex 73/4699 82/10654 1.488614639324471e-17 1.2743993619582667e-16 5.178620889049187e-17 8454/5689/5682/5526/1452/143471/5705/5709/9978/5695/5711/5683/324/5699/8312/5702/5518/5696/5691/7314/5515/5718/8945/5700/122706/5707/23198/5528/9861/5519/2932/5698/5692/5713/5710/5719/6233/10023/5706/23401/5714/6934/5688/5687/5708/5529/5704/7311/5694/5516/5684/5720/1487/1499/5525/139285/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/3065/5527/1488/5716/5693/5721 73 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-983705 Signaling by the B Cell Receptor (BCR) 93/4699 112/10654 1.5918424984944077e-17 1.3545132532643325e-16 5.504169915049244e-17 5295/8454/5689/5777/4893/4790/5579/5682/143471/5705/5530/5709/5695/4792/5711/5683/2534/5699/5702/30011/2885/4794/3845/3265/3551/5696/5691/7314/5718/8945/4773/5966/80228/5700/122706/5707/5336/23198/10892/8517/5970/9861/5698/5692/5713/5710/5478/5719/6233/7409/801/4772/4775/930/5706/6850/8915/5714/5688/5687/4067/5708/695/6654/5704/7311/5293/5694/1147/5684/5720/6885/4690/84433/5690/5532/5717/9491/6500/10197/7316/10213/10768/4793/5715/5701/23291/5685/5686/5534/5716/5693/5721 93 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-167161 HIV Transcription Initiation 47/4699 47/10654 1.7181014067378373e-17 1.4106516813215928e-16 5.732292782098541e-17 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-167162 RNA Polymerase II HIV Promoter Escape 47/4699 47/10654 1.7181014067378373e-17 1.4106516813215928e-16 5.732292782098541e-17 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-73776 RNA Polymerase II Promoter Escape 47/4699 47/10654 1.7181014067378373e-17 1.4106516813215928e-16 5.732292782098541e-17 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 47/4699 47/10654 1.7181014067378373e-17 1.4106516813215928e-16 5.732292782098541e-17 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-75953 RNA Polymerase II Transcription Initiation 47/4699 47/10654 1.7181014067378373e-17 1.4106516813215928e-16 5.732292782098541e-17 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 47/4699 47/10654 1.7181014067378373e-17 1.4106516813215928e-16 5.732292782098541e-17 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-180534 Vpu mediated degradation of CD4 51/4699 52/10654 1.882996133516797e-17 1.502117370146354e-16 6.103970719892966e-17 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/920/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 51/4699 52/10654 1.882996133516797e-17 1.502117370146354e-16 6.103970719892966e-17 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69610 p53-Independent DNA Damage Response 51/4699 52/10654 1.882996133516797e-17 1.502117370146354e-16 6.103970719892966e-17 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 51/4699 52/10654 1.882996133516797e-17 1.502117370146354e-16 6.103970719892966e-17 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 51/4699 52/10654 1.882996133516797e-17 1.502117370146354e-16 6.103970719892966e-17 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/2932/5698/5692/5713/595/5710/5719/6233/1019/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69481 G2/M Checkpoints 127/4699 168/10654 6.061275117254156e-17 4.807926703177873e-16 1.9537383964030643e-16 5689/83990/5682/9156/1763/7531/7486/10971/5982/7533/2810/11200/143471/472/5705/5709/4174/5695/84515/4998/5711/4683/10926/5683/990/165918/84126/5699/5702/8924/55388/672/6117/7334/5001/7465/5696/83695/5691/7314/5718/6118/23594/5700/122706/5707/51588/51720/23198/63967/7534/993/116028/983/9861/9656/5698/5692/5985/5713/4175/5710/7157/5984/5719/6233/7158/5884/5810/4999/4172/80010/5000/8318/51512/7532/4173/5706/9133/580/11073/891/641/5714/6119/3364/10524/5688/5687/144715/5708/1111/5704/23595/7311/5983/5694/4176/7529/1017/5684/5720/5883/10111/8317/5690/5717/9491/545/10197/7336/7316/10213/4171/5715/9088/7341/5701/5685/5686/995/5716/5932/79184/7156/5693/5721 127 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 49/4699 50/10654 9.422404867626381e-17 7.432054176487326e-16 3.0200729971930805e-16 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 49 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9604323 Negative regulation of NOTCH4 signaling 52/4699 54/10654 1.2946172160557257e-16 1.015442777286167e-15 4.1263306739323926e-16 8454/5689/5682/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/5707/7534/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/4855/5704/7311/5694/5684/5720/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721 52 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-72764 Eukaryotic Translation Termination 79/4699 93/10654 3.1177867839609417e-16 2.4318736914895346e-15 9.8821078181686e-16 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6192/6156/6143/6139/3921/6208/6170/6203/6147/6222/2935/6134/6155/6231/6142/23521/6207/6233/6188/200916/6122/6230/6194/2107/6136/6125/6232/6160/6193/6210/6229/6205/140801/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6217/6152/51065/6141/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 79 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2219528 PI3K/AKT Signaling in Cancer 84/4699 101/10654 4.901903125173067e-16 3.802360214222644e-15 1.5451186355590594e-15 5295/2308/374/2250/5291/3082/941/2064/2534/9965/2264/9542/2885/2475/8660/2252/5879/5290/3667/8823/2065/3815/84335/8074/7249/2260/2249/6714/2099/2248/2932/2247/10000/7409/2246/2251/3932/2931/5781/940/253260/5170/572/4303/930/6199/2263/4233/64223/8503/5159/29851/3084/208/10718/79109/5293/1956/2549/1147/2309/842/207/1027/8817/2100/2254/152831/1950/1026/50852/26281/10818/2261/2255/3164/5728/2066/27006/942/1385/5296/5156/4193 84 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2132295 MHC class II antigen presentation 98/4699 123/10654 5.013659428870539e-16 3.867680130842987e-15 1.5716618915256403e-15 162/51807/10484/1174/347688/1785/10381/1780/3115/1509/8655/3109/1510/832/3113/10112/972/7846/5476/3117/9632/81027/6456/11004/8722/3112/163/1759/3127/81930/161/10053/29127/1515/22872/3111/3796/10437/89953/56992/10376/10540/3835/51128/1213/1211/9493/6396/1175/7879/140735/8907/1508/1514/3902/3831/3120/1173/84617/1783/10382/10802/821/55860/830/3123/3832/7277/160/3122/1639/26052/1062/51143/9871/10383/24137/84790/84643/8905/1075/7280/829/1778/164/3119/10120/130340/1512/1781/1513/5641/10121/1519/1520/3799/375/10427 98 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/4699 52/10654 6.246847810099545e-16 4.7926635657812904e-15 1.9475361018544455e-15 5689/5682/143471/472/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1226099 Signaling by FGFR in disease 58/4699 63/10654 8.302158684363864e-16 6.3349080395906875e-15 2.5742391343965758e-15 5295/4893/11052/2250/5335/9530/613/5431/6776/5435/5433/11064/5439/2264/2885/9846/2252/3845/3265/7750/8805/26127/5290/8823/8074/2260/5438/2249/2248/399687/2247/2246/2251/6777/2963/5434/5436/6774/2263/6772/2962/6654/11160/2549/5432/22916/5440/5430/8817/5441/2254/4686/26281/10818/2261/5437/2255/27006 58 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-167172 Transcription of the HIV genome 65/4699 73/10654 8.997054933079969e-16 6.791325336582945e-15 2.759707851572917e-15 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/11198/904/51497/2959/404672/5438/83860/2068/1025/6883/7936/6829/2957/25920/2963/5434/5436/6878/4331/8148/2966/2962/54457/8812/905/2071/6880/6908/6882/2961/5432/22916/6877/6917/5440/902/5430/6749/5441/7469/4686/6872/8731/6879/9150/2958/5437/6827/2968/138474/1022/8178 65 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654738 Signaling by FGFR2 65/4699 73/10654 8.997054933079969e-16 6.791325336582945e-15 2.759707851572917e-15 5295/4893/2250/5335/54845/5431/5435/5433/8569/5439/7072/2885/7073/5518/2252/3845/3265/7314/5515/5290/8823/5594/8074/5438/3185/2249/6714/2248/4670/2247/6233/2246/2251/5781/5725/2963/5434/6464/5436/673/2263/2962/6654/7311/2549/5432/22916/5595/5516/10253/5440/5430/3178/8817/5441/2254/4686/7316/26281/10818/867/5437/2255/27006/3187 65 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-73762 RNA Polymerase I Transcription Initiation 46/4699 47/10654 1.0506450420596724e-15 7.888265449474759e-15 3.20545799491327e-15 2074/9112/5435/5928/2965/64425/1107/2967/2648/30834/404672/8850/57459/2068/3066/9533/5434/9015/79101/9219/5931/221830/7270/4331/9013/1108/2966/54815/2071/10849/57504/6908/53615/5440/902/9014/25885/5441/51082/7343/5437/3065/2968/84172/1022/10919 46 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 55/4699 59/10654 1.1243039729454873e-15 8.396397755401404e-15 3.4119415080428563e-15 6227/6206/1965/6234/27335/6191/8668/6224/8662/26986/6202/6218/6192/1973/3921/8665/6208/6203/8666/6222/8667/6231/8663/8894/1981/6207/1977/6233/51386/6188/1978/1968/6230/8669/6194/6232/6193/6210/6229/6205/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/6204/6228/3646/6189/6201 55 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 49/4699 51/10654 1.3704775315318645e-15 1.0180690234236708e-14 4.137002629296968e-15 5689/5682/143471/5705/5709/5695/5711/4946/5683/5699/5702/5696/5691/5718/1728/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/5706/4947/5714/5688/5687/5708/4953/5704/5694/5684/5720/5690/51686/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 49 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-3371453 Regulation of HSF1-mediated heat shock response 62/4699 69/10654 1.5157637054272713e-15 1.1200696012736257e-14 4.551489907709591e-15 23165/6782/573/7531/9530/348995/472/57122/3313/23511/3305/23279/259217/23225/3309/3306/9972/23411/8021/6117/3312/55746/51182/3303/6118/5594/3308/10049/3337/10762/9261/79902/9883/2932/6396/129401/3297/4928/5903/55706/7175/4927/6119/57805/3310/7266/8086/3304/5595/81929/9631/116835/545/79023/23636/10808/53371/9532/9688/22824/9529/8480 62 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2408557 Selenocysteine synthesis 78/4699 93/10654 2.139263773156428e-15 1.5725268782783375e-14 6.390085230370813e-15 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6192/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/51091/6188/200916/6122/6230/6194/6136/6125/6232/6160/6193/6210/6229/6205/140801/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6217/6152/51065/6141/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 78 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-72649 Translation initiation complex formation 54/4699 58/10654 2.393356139809874e-15 1.7410735856440743e-14 7.074987879885203e-15 6227/6206/1965/6234/27335/6191/8668/6224/8662/26986/6202/6218/6192/1973/3921/8665/6208/6203/8666/6222/8667/6231/8663/8894/1981/6207/1977/6233/51386/6188/1968/6230/8669/6194/6232/6193/6210/6229/6205/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/6204/6228/3646/6189/6201 54 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-72702 Ribosomal scanning and start codon recognition 54/4699 58/10654 2.393356139809874e-15 1.7410735856440743e-14 7.074987879885203e-15 6227/6206/1965/6234/27335/6191/8668/6224/8662/6202/6218/6192/1973/3921/8665/6208/6203/8666/6222/8667/6231/8663/8894/1981/6207/1977/6233/51386/6188/1968/6230/8669/6194/1983/6232/6193/6210/6229/6205/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/6204/6228/3646/6189/6201 54 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 59/4699 65/10654 2.43248338521374e-15 1.751388037353893e-14 7.116901456333857e-15 2074/5982/5431/5435/9978/5433/2965/5439/2967/6117/10714/91603/7314/6118/404672/5438/3978/5985/2068/5984/6233/7874/5424/8451/10450/5434/5436/7515/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/2071/51426/7311/3980/5983/5432/56655/6917/5440/902/27339/5430/5441/7316/5437/2033/2968/56949/9716/5981/1022 59 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9614085 FOXO-mediated transcription 59/4699 65/10654 2.43248338521374e-15 1.751388037353893e-14 7.116901456333857e-15 2308/857/2290/65018/57060/356/10971/7295/2810/84676/4089/1647/1387/4088/10628/4801/3630/56729/23411/2538/7534/847/5934/5443/8850/10000/3066/604/2645/5105/7532/4303/23410/4287/4800/901/9314/10370/2908/6794/4852/6648/4087/208/25942/7529/27113/2309/10018/4802/207/1027/6720/1649/114907/1026/2033/3065/10891 59 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-195258 RHO GTPase Effectors 214/4699 327/10654 2.5375014002143375e-15 1.81767957443925e-14 7.386282271300598e-15 55839/11130/71/6249/51517/5579/9735/7531/5526/51807/10811/10971/5578/9212/347688/388/7533/2810/147841/348995/10381/57122/6280/1780/23122/5048/57405/8655/10094/23279/1432/2017/2491/7846/79784/9475/1060/81027/4628/11004/8976/1855/2885/6093/9184/8826/10499/5518/23332/25909/3071/10726/81930/5062/55746/5879/5515/26999/25/79682/1072/10403/4638/25936/4659/10093/1856/10006/4771/389/5594/3619/64105/7534/332/5528/6714/79902/3796/5519/81565/999/89953/10810/91687/11243/10376/23002/11113/83540/5580/1857/9055/23191/7514/54820/6396/1535/5600/801/64946/9793/30849/10109/5586/140735/5500/10787/4221/3831/220134/5170/84617/4928/5590/5903/653361/55055/5747/80776/1783/401541/2316/7532/10382/10627/79172/7277/79980/6232/5501/10152/6279/54821/10092/9183/10163/1062/699/22919/55845/5063/3895/5529/51143/998/695/10788/10097/57120/367/10383/5347/387/60/84790/84643/5058/4660/7280/4629/7529/5595/1778/5516/5905/81929/54908/55143/1495/1499/5525/4690/1058/991/79019/4627/348235/80152/10458/1063/6722/8379/1027/1080/23421/55920/79023/6242/1781/10398/4085/5585/5216/10552/81624/55166/8936/4637/51466/995/79003/23028/5527/10096/701/23380/9928/29941/3799/103910/57551/5300/10095 214 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-180585 Vif-mediated degradation of APOBEC3G 51/4699 54/10654 2.9201257865991815e-15 2.081145484459518e-14 8.456896480559745e-15 5689/5682/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/60489/5706/5714/5688/5687/5708/5704/7311/5694/5684/8065/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 90/4699 112/10654 2.9728449110246987e-15 2.1080173005447865e-14 8.566092194446501e-15 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6728/6192/6156/6143/6139/3921/6208/6170/6203/10952/6147/6222/6727/6184/6134/6731/6155/6729/6231/6142/23521/6185/6207/6726/6233/6188/200916/6122/6230/6194/1650/6136/6125/6232/6160/6748/29927/6193/6210/6229/6205/140801/6181/23471/7311/6223/25873/6730/9045/6187/6168/6157/6137/6144/9349/4736/51121/6217/6152/51065/6141/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 90 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5658442 Regulation of RAS by GAPs 61/4699 68/10654 3.1133448067462195e-15 2.1965508083777348e-14 8.92585498681011e-15 5689/4893/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/3845/3265/4763/5696/5691/7314/5718/5700/122706/5707/23198/5921/9861/5698/5692/5713/5710/5719/6233/200734/9462/5706/84078/5714/5688/5687/5708/5704/7311/5694/5684/5720/153090/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/399473/5693/5721/161742 61 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5688426 Deubiquitination 197/4699 297/10654 4.337117446015699e-15 3.04465644710302e-14 1.2372198188107941e-14 5689/221937/5682/79594/7419/10474/7321/4738/7375/9817/10445/91833/6478/3091/143471/5705/11274/55031/8239/5709/5695/4792/11047/4609/4194/4089/5711/7347/4088/114803/5683/324/408/5699/8312/5702/8900/57599/377630/672/6881/51616/7187/7040/7345/3054/1540/80351/5696/5691/7314/5718/3607/6314/90865/2648/5700/122706/5707/8027/8737/83444/8767/171023/55611/51720/57646/23198/63967/8517/86/993/890/7417/983/4092/2099/1643/9861/23586/81847/64426/8850/7128/29844/7046/6502/5698/9146/5692/5713/5710/10454/8473/7157/9958/8313/5719/54891/6233/9804/55593/93973/10318/23770/8607/7874/5886/10600/51651/8237/4303/409/330/5706/4287/27005/7706/580/7416/79155/25862/9738/8658/84132/5714/79589/27430/64127/5688/9097/5687/5708/4087/63891/7189/5704/7048/7311/367/114548/387/60/5694/7528/9960/23358/23032/5684/8295/5720/10617/7186/56957/6885/991/51377/10392/5690/2625/57506/5717/9491/4086/1080/10197/64750/7316/10213/8314/8678/9100/7415/5715/283899/5701/4798/329/79913/9099/5685/54617/5686/2033/221656/5728/10868/123228/5716/79184/78990/5887/5693/154/10254/5721/4193 197 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-187037 Signaling by NTRK1 (TRKA) 69/4699 80/10654 4.725069055084049e-15 3.300495996685574e-14 1.3411822088795783e-14 5295/9252/4893/5335/5291/1848/1785/5605/1432/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5515/5607/161/5290/3667/1849/5594/5528/9261/6714/5519/5598/4208/4914/6195/1213/1211/5600/1175/6300/1846/1173/6464/135/160/673/6774/26052/7867/6654/5900/387/7529/5595/5516/1845/4915/5604/4205/10818/466/4803/2002/1398/1385/5906/5296 69 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-4608870 Asymmetric localization of PCP proteins 58/4699 64/10654 5.045257388005166e-15 3.5067036498808185e-14 1.4249762919743618e-14 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/2535/5700/122706/5707/1856/8322/23198/9861/8321/5698/5692/5713/5710/5719/6233/7474/7855/144165/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/23513/5716/5693/5721 58 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5674135 MAP2K and MAPK activation 40/4699 40/10654 5.485957264546173e-15 3.79422857114425e-14 1.5418142791724274e-14 4893/71/84292/5908/22866/5605/5037/2244/54756/3690/408/5894/8826/4140/3845/3265/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/28956/283455/3674/409/673/7450/60/7529/5595/5604/54518/10256/8649/5906 40 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-169911 Regulation of Apoptosis 50/4699 53/10654 6.294454229422217e-15 4.332065557896468e-14 1.7603685203028082e-14 5689/5682/4976/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 47/4699 49/10654 6.578607447308133e-15 4.5055438322051796e-14 1.8308627658233675e-14 9134/57060/2810/1869/6790/25904/1647/8900/55571/55835/57472/144455/85456/29883/1263/7027/7832/898/5934/890/10769/983/7157/5325/79733/1820/4869/4850/891/5111/246175/4848/23019/1874/1017/25946/4849/1027/9337/1026/5933/28984/2033/995/10498/581/3276 47 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-388841 Costimulation by the CD28 family 62/4699 70/10654 7.553329827372154e-15 5.147997610500245e-14 2.0919288535696006e-14 5295/5777/5526/151888/941/3115/3113/3117/2534/2885/2475/5518/3127/5062/5879/5515/1326/5290/5133/57761/5528/9020/6714/5519/29126/10000/1445/916/7525/7409/3932/5781/1493/940/253260/3120/5170/3123/80380/3122/920/64223/8503/4067/29851/5063/5529/998/208/79109/5058/5516/9402/5525/3119/207/919/915/917/942/5527/5296 62 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9013694 Signaling by NOTCH4 70/4699 82/10654 9.293233969311379e-15 6.303236953098152e-14 2.5613693421646417e-14 8454/5689/5682/23385/5705/5709/9978/5695/22938/5711/1387/4088/5683/5699/4853/5702/9794/5696/5691/7314/5718/2648/5700/5707/55534/3280/84441/7534/9861/8850/5698/5692/5713/5710/5719/6233/5663/5706/10046/5714/5688/5687/5708/59/4855/5704/7311/5694/4851/5684/5720/23462/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/2033/55294/5716/3516/5693/5721 70 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-4420097 VEGFA-VEGFR2 Pathway 81/4699 99/10654 1.0546839519490354e-14 7.119116675655989e-14 2.8929084107104116e-14 5295/4893/857/5335/71/5579/5291/5578/1432/2534/9475/3690/5603/2475/6093/8440/3845/3265/3071/8877/5062/5829/5879/26999/5290/5567/10006/57761/5921/1500/9261/6714/10810/10000/3728/5580/7409/23191/3685/3791/1535/5600/6300/801/10787/253260/5170/5590/653361/5747/5568/3315/10152/7867/64223/5566/1003/10163/55845/5063/998/208/79109/2185/387/60/5058/558/1495/1499/4690/207/7422/10458/9047/10768/8936/3320/4846/1398/5296 81 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-73894 DNA Repair 216/4699 334/10654 1.2672636581114258e-14 8.51310132051886e-14 3.4593649090727417e-14 2237/4436/83990/151987/9156/2074/1763/7486/4913/56852/10445/5982/11200/472/6613/7507/80198/3981/5431/5435/9978/5433/26277/10980/64421/4683/2965/25898/165918/84126/5439/10987/8900/8924/57599/2067/672/2967/6612/6117/7334/10973/10714/54386/91603/83695/55183/7314/51514/7014/6118/2176/25/5888/328/83444/51588/51720/63967/404672/5531/9636/86/5438/3978/11201/116028/2070/890/9031/1643/7517/9656/84464/51455/29844/2177/5985/10920/29089/2068/7157/5984/4595/4255/54891/6233/7158/6047/93973/55247/8607/7874/5884/5810/5424/2188/5886/57697/8451/8554/10450/8467/80010/124739/3838/5434/5436/2956/7515/54107/7013/4292/7706/51567/580/11073/5591/8450/4331/5425/641/5111/2966/6119/3364/22976/10524/5427/144715/1161/1642/142/1111/2071/55215/1069/7329/9246/79728/51426/2873/146956/7311/7318/4968/3980/60/5536/8533/5983/2175/2547/5432/51138/7528/56655/9318/11284/51750/1017/54962/6917/5440/5893/2178/902/5883/27339/5430/10111/7320/7520/675/51548/545/5441/7336/54778/7316/6996/64708/8314/9100/10635/10459/7415/5395/283899/7341/4798/5437/51008/79913/54617/65057/2033/8914/7398/2968/5932/2189/55120/2187/79184/56949/7156/5887/9716/5599/5981/1022/8178/50813/7508/7374 216 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 46/4699 48/10654 1.4393214187088614e-14 9.622891770796387e-14 3.9103368869183106e-14 5295/5777/1437/5291/6776/3558/3717/2534/3563/2885/9846/1399/7314/3635/5290/1439/7534/3718/3567/6233/7525/7409/6777/5781/3562/6464/1438/6850/5566/8503/4067/3636/6654/7006/3716/7311/5293/3561/3568/7316/3560/3055/867/1398/5296/3559 46 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-380108 Chemokine receptors bind chemokines 54/4699 59/10654 1.6099119541945403e-14 1.071239992269732e-13 4.3530669951281665e-14 729230/7852/1237/6349/3576/6360/2920/2921/1236/6370/58191/1524/643/2833/6347/6387/10663/3579/6375/6846/6367/2826/6376/6354/3627/6346/9034/2829/1233/6366/6373/6357/6361/10803/6351/3577/10563/10850/5473/4283/6356/56477/1234/57007/6374/1230/2919/5196/6352/6348/6364/6372/6363/1232 54 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-190236 Signaling by FGFR 73/4699 87/10654 1.6387122349531665e-14 1.0852603669218141e-13 4.410039877580021e-14 5295/4893/2250/5335/54845/5431/5435/5433/8569/9965/5439/2264/7072/2885/7073/5518/2252/3845/3265/7314/5515/5290/8823/5594/8074/2260/5438/3185/2249/6714/2248/4670/2247/6233/2246/2251/200734/5781/5725/2963/5434/6464/5436/673/2263/2962/6654/7311/53834/2549/5432/22916/5595/5516/10253/5440/5430/3178/8817/5441/2254/4686/7316/152831/26281/10818/2261/867/5437/2255/27006/3187/161742 73 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-390466 Chaperonin-mediated protein folding 78/4699 95/10654 2.2732634423301427e-14 1.4984328042401504e-13 6.088998199866258e-14 2788/9134/1459/2770/51807/10528/1460/10381/2775/10576/1457/7846/2782/81027/10574/6468/10564/54461/10693/8877/2773/2787/5204/10575/10681/898/10517/2792/10471/26985/2785/10376/2783/26190/2784/10238/7157/2771/83752/2791/26224/84617/2781/8237/10382/7277/6774/26272/26270/55135/5082/2786/10383/60/84790/22948/7280/84261/10694/8841/54331/22803/59345/5203/51764/94235/7203/908/55970/346562/11328/2793/6950/3801/55294/6499/26234/2790 78 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 48/4699 51/10654 2.914044715493997e-14 1.9118312058661552e-13 7.768874745684932e-14 6227/6206/1965/6234/27335/6191/8668/6224/8662/6202/6218/6192/3921/8665/6208/6203/8666/6222/8667/6231/8663/8894/6207/6233/51386/6188/1968/6230/8669/6194/6232/6193/6210/6229/6205/6223/8664/6187/6217/51065/10480/8661/6209/6204/6228/3646/6189/6201 48 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6783783 Interleukin-10 signaling 45/4699 47/10654 3.145989105007929e-14 2.0544040481075035e-13 8.348230574855804e-14 729230/7124/1437/3593/5743/941/3383/6349/3576/2920/1435/7133/3606/6347/3588/3569/3592/3587/6367/3976/3627/7076/7850/7297/3557/6351/6774/1440/3552/3716/1234/3586/3554/2208/3553/1230/2919/2357/6352/6348/6364/7132/942/6363/5724 45 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5358351 Signaling by Hedgehog 111/4699 149/10654 3.287810309994786e-14 2.1370767014966108e-13 8.684177329518393e-14 8454/5689/5682/22873/1452/51684/143471/10381/5705/8452/5709/9978/5695/107/3549/5711/7846/5683/408/5699/5702/81027/83737/6868/6469/5696/5691/7314/5718/8945/339745/5700/122706/5707/5567/27152/23198/112/5573/2737/5727/8650/111/50846/9861/8405/2932/5698/5692/5713/10376/5710/5719/6233/23322/196883/115/84617/54903/10382/5568/409/79577/7277/5706/113/84447/5714/5566/2736/5688/5687/5708/5577/5704/7311/10383/84790/5694/7280/109/57154/5684/5720/2735/5575/6608/5690/5717/9491/6500/114/7289/10197/108/64750/132884/7316/10213/2778/7415/5715/5701/5576/5685/5686/5716/8481/5693/5721/5034 111 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 50/4699 54/10654 4.8473559764710235e-14 3.136261654822727e-13 1.274444307177926e-13 2074/7507/5431/5435/9978/5433/10980/2965/5439/10987/2967/91603/7314/404672/5438/10920/2068/6233/7874/8451/10450/5434/5436/8450/4331/2966/1161/1642/2071/2873/7311/8533/5432/51138/9318/6917/5440/902/27339/5430/5441/7316/64708/5437/2033/2968/56949/9716/1022/50813 50 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5632684 Hedgehog 'on' state 71/4699 85/10654 6.032853784132871e-14 3.885379226111262e-13 1.578854056494455e-13 5689/5682/22873/1452/51684/143471/5705/8452/5709/9978/5695/3549/5711/5683/408/5699/5702/83737/6469/5696/5691/7314/5718/339745/5700/122706/5707/23198/2737/5727/8650/50846/9861/8405/5698/5692/5713/5710/5719/6233/409/79577/5706/5714/2736/5688/5687/5708/5704/7311/5694/57154/5684/5720/2735/6608/5690/5717/9491/10197/64750/132884/7316/10213/5715/5701/5685/5686/5716/5693/5721 71 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 47/4699 50/10654 6.258071000427013e-14 4.0120236002737565e-13 1.6303169825673833e-13 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/2209/5706/50489/5714/5688/5687/5708/5704/5694/5684/5720/5690/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721/4360 47 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-176187 Activation of ATR in response to replication stress 37/4699 37/10654 6.481833291165332e-14 4.13658815490733e-13 1.680934757804598e-13 5982/4174/84515/4998/10926/990/84126/55388/6117/5001/6118/23594/63967/993/5985/4175/5984/5884/5810/4999/4172/5000/8318/4173/6119/3364/144715/1111/23595/5983/4176/1017/5883/8317/545/4171/995 37 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-400253 Circadian Clock 61/4699 70/10654 6.77655477590577e-14 4.305105387046018e-13 1.7494130452683628e-13 8454/79718/5936/28999/3091/5469/1387/150094/6907/5499/10499/23054/1386/9575/23411/85441/96764/7314/5054/8945/10135/1454/5465/64784/4208/6604/80205/6233/8864/1453/5500/5187/26224/1374/1407/4783/406/4209/5501/8553/2908/1390/7311/23373/6095/8841/8204/6500/200186/1408/6720/7316/9611/2033/79365/6256/10498/1385/8648/551/10891 61 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-166520 Signaling by NTRKs 81/4699 101/10654 9.072109635433835e-14 5.711767680784352e-13 2.321021204817153e-13 5295/627/9252/4893/5335/5291/1848/1785/5605/1432/2534/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5879/5515/5607/161/5290/3667/1849/5594/5528/9261/6714/5519/5598/4208/4914/6195/1213/1211/5600/1175/6300/5781/1846/25920/1173/5800/6464/2904/135/7074/160/673/6774/26052/7867/6654/5900/387/2549/1020/7529/5595/5516/1845/4915/5604/4205/10818/466/4803/2002/1398/1385/5906/8851/5296/581 81 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-391251 Protein folding 81/4699 101/10654 9.072109635433835e-14 5.711767680784352e-13 2.321021204817153e-13 2788/9134/1459/2770/51807/10528/1460/10381/2775/10576/1457/7846/2782/81027/10574/6468/10564/54461/10693/8877/2773/2787/402/5204/10575/10681/898/10517/2792/10471/26985/2785/10376/2783/26190/2784/10238/7157/2771/83752/2791/26224/84617/2781/8237/10382/7277/6774/26272/26270/55135/5082/2786/10383/60/84790/22948/7280/84261/10694/8841/54331/22803/59345/5203/51764/94235/7203/908/55970/6902/346562/11328/1155/2793/6950/3801/55294/6499/26234/2790 81 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-191859 snRNP Assembly 49/4699 53/10654 1.0245374407449523e-13 6.393113630248502e-13 2.597891428695973e-13 23165/6633/6606/8487/25929/348995/57122/23511/23279/23225/79084/9972/8021/55746/96764/10762/79902/9883/6636/10419/6396/129401/50628/4928/6635/5903/6632/55706/7175/6637/54960/4927/51808/8086/79833/22916/81929/11218/9631/79023/23636/10073/4686/53371/9688/6634/8480/6628/79760 49 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-194441 Metabolism of non-coding RNA 49/4699 53/10654 1.0245374407449523e-13 6.393113630248502e-13 2.597891428695973e-13 23165/6633/6606/8487/25929/348995/57122/23511/23279/23225/79084/9972/8021/55746/96764/10762/79902/9883/6636/10419/6396/129401/50628/4928/6635/5903/6632/55706/7175/6637/54960/4927/51808/8086/79833/22916/81929/11218/9631/79023/23636/10073/4686/53371/9688/6634/8480/6628/79760 49 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 131/4699 185/10654 1.1807183974399254e-13 7.335082433653342e-13 2.9806677755586386e-13 6158/5393/6138/6227/6206/6234/6191/6128/6132/6129/23404/6176/10528/84135/27043/6224/6146/6154/6202/51096/6169/55272/6175/6218/28987/23481/6192/6156/117246/6143/6139/23160/26168/11340/3921/6208/6170/22984/10813/9136/6203/6147/6222/1454/56902/51602/6134/6155/6231/6142/23521/10171/5822/6207/10969/6233/6188/79707/1453/4691/23016/118460/200916/6122/6230/2091/55127/6194/8780/9277/6136/6125/6232/90459/6160/6193/10200/6210/6229/6205/11056/9790/140801/6181/55759/705/7311/6223/25873/51010/26354/56915/51202/9045/6187/6168/6157/6137/22894/84946/6144/9349/55813/4736/22803/51121/25879/6217/81887/6152/57050/51065/6141/55781/6209/11224/6165/6130/6204/6228/51013/6124/83732/27341/6189/6135/6201/6161/54512/6133/9188 131 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6782135 Dual incision in TC-NER 58/4699 66/10654 1.254971950194645e-13 7.762029154507848e-13 3.154160894994193e-13 2074/5982/7507/5431/5435/9978/5433/2965/5439/2067/2967/6117/10714/91603/7314/6118/404672/5438/5985/2068/5984/6233/7874/5424/8451/10450/5434/5436/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/2071/51426/7311/5983/5432/56655/6917/5440/902/27339/5430/5441/7316/5437/2033/2968/56949/9716/5981/1022 58 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 51/4699 56/10654 1.4629274888699743e-13 9.008553484094053e-13 3.6606957477725126e-13 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/6469/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 51 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 36/4699 36/10654 1.4759619533689334e-13 9.049129181353635e-13 3.677183997821016e-13 4893/71/5908/22866/5605/5037/2244/3690/408/5894/8826/4140/3845/3265/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/283455/3674/409/673/7450/60/7529/5595/5604/54518/10256/5906 36 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5387390 Hh mutants abrogate ligand secretion 53/4699 59/10654 1.886995013155015e-13 1.1518873906389745e-12 4.680783968558435e-13 5689/5682/143471/5705/5709/5695/3549/5711/5683/5699/5702/6469/5696/5691/7314/5718/5700/122706/5707/23198/50846/9861/5698/5692/5713/5710/5719/6233/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 53 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 57/4699 65/10654 2.520768720667121e-13 1.5321035860678086e-12 6.225822039651764e-13 3725/4436/472/5431/5435/5433/2965/5439/672/2967/1386/11198/904/51497/2176/404672/5438/1643/9656/2177/2068/7157/1025/2353/7936/6829/25920/2963/5434/5436/4292/4331/2966/2962/8812/905/1111/2071/55215/5432/6917/5440/8621/902/5430/6749/545/5441/7469/5395/9150/5437/51755/6827/2968/1022/8178 57 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 65/4699 77/10654 2.5858524778737986e-13 1.5581703343067868e-12 6.331746297752876e-13 1912/23165/7486/6045/80012/10274/348995/6613/57122/23511/1911/6672/23279/23225/165918/57332/5371/8924/672/9972/6612/8021/6117/55746/51564/51588/10762/79902/9656/9883/84733/9063/6396/129401/7703/6015/8554/4928/5903/55706/7175/1029/8535/5885/641/4927/8243/142/1069/8086/7329/648/81929/5893/9631/79023/23636/10735/53371/6996/9688/7341/9126/8480/7508 65 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9009391 Extra-nuclear estrogen signaling 65/4699 77/10654 2.5858524778737986e-13 1.5581703343067868e-12 6.331746297752876e-13 5295/2788/374/4893/857/2770/2782/3845/3265/8877/2773/2787/5290/4316/5594/10681/4313/2792/6714/2099/10000/2785/595/2783/2784/2771/7514/2353/801/2791/5170/5590/6464/5747/1903/3315/4318/8503/2786/208/1956/3480/5595/596/54331/2309/59345/207/6722/1027/51764/94235/2100/1950/55970/4314/346562/2793/3320/4846/2002/1385/5296/3276/2790 65 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-112382 Formation of RNA Pol II elongation complex 54/4699 61/10654 4.560842462666015e-13 2.713314753213172e-12 1.102576545390268e-12 5431/5435/5433/2965/5439/2967/11198/904/51497/4300/80349/404672/5438/2068/1025/23168/55677/7936/6829/123169/25920/85403/2963/5434/5436/9646/79577/4331/2966/2962/4298/8812/905/2071/27125/5432/22916/55840/6917/5440/902/6830/5430/6749/5441/7469/4686/9150/54623/5437/6827/2968/1022/8178 54 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5678895 Defective CFTR causes cystic fibrosis 54/4699 61/10654 4.560842462666015e-13 2.713314753213172e-12 1.102576545390268e-12 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/79139/91445/23198/9861/5698/5692/5713/5710/5719/6233/6048/5706/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 54 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-75955 RNA Polymerase II Transcription Elongation 54/4699 61/10654 4.560842462666015e-13 2.713314753213172e-12 1.102576545390268e-12 5431/5435/5433/2965/5439/2967/11198/904/51497/4300/80349/404672/5438/2068/1025/23168/55677/7936/6829/123169/25920/85403/2963/5434/5436/9646/79577/4331/2966/2962/4298/8812/905/2071/27125/5432/22916/55840/6917/5440/902/6830/5430/6749/5441/7469/4686/9150/54623/5437/6827/2968/1022/8178 54 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 44/4699 47/10654 6.147882739257165e-13 3.5965114024654413e-12 1.4614703704725366e-12 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/283455/3674/409/673/816/7450/60/7529/5595/815/5604/54518/10256/5906/5245 44 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6802949 Signaling by RAS mutants 44/4699 47/10654 6.147882739257165e-13 3.5965114024654413e-12 1.4614703704725366e-12 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/283455/3674/409/673/816/7450/60/7529/5595/815/5604/54518/10256/5906/5245 44 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 44/4699 47/10654 6.147882739257165e-13 3.5965114024654413e-12 1.4614703704725366e-12 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/283455/3674/409/673/816/7450/60/7529/5595/815/5604/54518/10256/5906/5245 44 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9649948 Signaling downstream of RAS mutants 44/4699 47/10654 6.147882739257165e-13 3.5965114024654413e-12 1.4614703704725366e-12 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/283455/3674/409/673/816/7450/60/7529/5595/815/5604/54518/10256/5906/5245 44 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-168325 Viral Messenger RNA Synthesis 41/4699 43/10654 7.105221753926801e-13 4.122203034096376e-12 1.6750892521219342e-12 23165/348995/57122/5431/23511/5435/5433/23279/23225/5439/9972/8021/55746/5438/10762/79902/9883/6396/129401/4928/2963/5434/5903/55706/7175/5436/4927/2962/8086/5432/81929/5440/9631/5430/79023/5441/23636/53371/9688/5437/8480 41 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5655253 Signaling by FGFR2 in disease 41/4699 43/10654 7.105221753926801e-13 4.122203034096376e-12 1.6750892521219342e-12 5295/4893/2250/5335/5431/5435/5433/5439/2885/2252/3845/3265/5290/8823/8074/5438/2249/2248/2247/2246/2251/2963/5434/5436/2263/2962/6654/2549/5432/22916/5440/5430/8817/5441/2254/4686/26281/10818/5437/2255/27006 41 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8868773 rRNA processing in the nucleus and cytosol 135/4699 195/10654 7.820462816835779e-13 4.518489627505116e-12 1.8361233903941923e-12 6158/5393/6138/6227/6206/6234/6191/6128/6132/6129/23404/55226/6176/10528/84135/27043/6224/6146/6154/6202/51096/6169/55272/6175/6218/28987/23481/6192/6156/117246/6143/6139/23160/26168/11340/3921/6208/6170/22984/10813/9136/6203/6147/6222/1454/56902/51602/6134/6155/6231/6142/23521/10171/5822/6207/10969/6233/6188/79707/1453/4691/23016/118460/200916/6122/6230/2091/55651/55127/6194/8780/9277/6136/6125/4839/6232/90459/6160/6193/10200/6210/6229/6205/11056/9790/140801/6181/55759/705/7311/6223/25873/51010/26354/56915/51202/9045/6187/6168/6157/6137/22894/84946/6144/9349/55813/4736/22803/51121/25879/6217/81887/6152/57050/51065/6141/55781/6209/11224/6165/6130/6204/1736/6228/51013/6124/83732/27341/6189/6135/6201/6161/54512/6133/9188 135 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 65/4699 78/10654 8.836701138070417e-13 5.084724753217568e-12 2.066217436080313e-12 3443/4790/7321/9140/9474/4792/177/3093/1387/83737/7187/1540/3551/7314/3445/6283/8737/29110/4214/9636/841/8517/3444/7323/5970/23586/7128/3451/3448/3661/3439/51191/6233/10010/55593/8772/3452/4791/3446/3665/351/54476/7706/843/3440/9246/7189/7311/7318/5094/3456/1147/3441/7186/57506/3449/7316/4793/3146/7322/2033/6288/54941/6285/5300 65 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5689603 UCH proteinases 80/4699 102/10654 1.2035572579510466e-12 6.89711995985008e-12 2.802698319267314e-12 5689/221937/5682/4738/10445/143471/5705/5709/5695/11047/5711/7347/5683/5699/5702/7040/7345/3054/5696/5691/7314/5718/3607/5700/122706/5707/83444/171023/23198/86/4092/9861/29844/7046/5698/5692/5713/5710/8473/9958/5719/54891/6233/93973/8607/5706/580/5714/5688/5687/5708/5704/7048/7311/60/5694/7528/5684/5720/51377/5690/5717/9491/10197/7316/10213/8314/5715/283899/5701/4798/79913/5685/54617/5686/221656/123228/5716/5693/5721 80 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8878171 Transcriptional regulation by RUNX1 159/4699 239/10654 1.381395881839132e-12 7.884064301228216e-12 3.203750825660289e-12 1912/9070/5689/1437/5579/5682/1459/6045/9021/5929/27327/80012/1460/143471/8013/5705/5709/5695/28996/1457/1911/6603/10413/5711/1387/3558/5683/10138/57332/5699/8312/5702/192669/83737/5371/6688/4343/5696/5691/7314/5718/25/4773/8861/5700/122706/5707/23198/86/865/1515/7082/23309/6714/2099/9861/8850/84733/5588/6604/8289/5698/5692/5713/6602/595/5710/3458/896/5719/23067/6233/161882/26523/5781/1493/23429/55193/6015/1514/55904/6595/3562/6597/6929/8535/3674/6938/3958/5706/6599/200845/4331/2623/5714/5688/5687/5708/6886/4602/5704/7311/7161/860/58508/25942/648/5694/6601/23466/4297/4004/27161/894/5684/5720/902/2624/11091/8085/5690/2625/57690/5717/9491/4005/6598/10197/192670/5196/7316/10213/5079/10398/1513/122809/5715/5701/5685/5686/2033/1021/84333/6605/50943/3065/861/23112/9757/5716/9739/8784/3276/3559/7057/1022/5693/5721/1997 159 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 40/4699 42/10654 1.5445250766784778e-12 8.779405699014505e-12 3.5675797637320907e-12 23165/348995/57122/23511/81608/23279/23225/9972/8021/55746/53981/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/7884/4927/10898/10482/51692/8086/22916/81929/9631/29894/79023/23636/4686/8189/53371/9688/10189/8480/55339 40 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-429914 Deadenylation-dependent mRNA decay 50/4699 56/10654 1.6202562909483692e-12 9.172741260046412e-12 3.7274147270543984e-12 5393/80153/23404/26986/28960/219988/25904/1973/10767/55571/11340/57472/85456/29883/80349/51690/11157/1981/1977/23016/118460/9924/23644/5073/27258/4850/255967/57819/246175/4848/23019/23658/1975/51010/56915/1974/167227/22894/1656/27257/4849/25804/9337/55802/51013/196513/9775/54464/6499/54512 50 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-113418 Formation of the Early Elongation Complex 33/4699 33/10654 1.7413809321531133e-12 9.779595314971883e-12 3.974014590429421e-12 5431/5435/5433/2965/5439/2967/51497/404672/5438/2068/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/7469/4686/9150/5437/6827/2968/1022 33 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 33/4699 33/10654 1.7413809321531133e-12 9.779595314971883e-12 3.974014590429421e-12 5431/5435/5433/2965/5439/2967/51497/404672/5438/2068/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/7469/4686/9150/5437/6827/2968/1022 33 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-351202 Metabolism of polyamines 52/4699 59/10654 1.8616799978588056e-12 1.0413540705154435e-11 4.2316232285152974e-12 5689/5682/143471/5705/5709/5695/5711/4946/5683/5699/5702/5696/5691/5718/1728/5700/122706/5707/23198/79814/9861/5698/5692/5713/5710/5719/6303/5706/4947/5714/5688/5687/5708/4953/5704/5694/5684/5720/5690/51686/5717/9491/10197/10213/5715/6611/5701/5685/5686/5716/5693/5721 52 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2980766 Nuclear Envelope Breakdown 47/4699 52/10654 2.704915291017217e-12 1.5070242335667353e-11 6.123910140899465e-12 23165/5579/91754/5578/348995/57122/23511/23279/23225/4001/9972/8021/55746/10762/983/79902/9883/7444/2010/64900/23175/6396/129401/4928/5903/55706/7175/9133/255919/891/4927/8086/5347/7112/4000/81929/9631/140609/10783/79023/23636/7443/53371/9688/8815/23399/8480 47 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-4615885 SUMOylation of DNA replication proteins 42/4699 45/10654 2.7993573795679628e-12 1.5534773758551065e-11 6.312676096217334e-12 23165/9212/348995/6613/57122/23511/6790/23279/23225/9972/6612/8021/55746/7150/51588/3619/7153/332/10762/79902/9883/7155/6396/129401/4928/5903/55706/7175/5111/4927/8086/7329/5905/81929/55143/9631/79023/23636/53371/9688/7341/8480 42 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 80/4699 103/10654 3.067065335802659e-12 1.6953384769554854e-11 6.889139709925575e-12 5295/374/3643/2250/5291/5526/3082/941/2064/2534/9965/2264/3630/3654/9542/2885/51135/8660/5518/2252/5879/5515/5290/3667/8823/90865/2065/3815/5594/8074/2260/5528/2249/6714/2099/2248/5519/2247/7409/2246/2251/3932/5781/940/930/2263/4233/8503/5159/29851/3084/5529/7189/10718/5293/1956/2549/5595/5516/5305/5525/8870/207/8817/4615/2100/2254/152831/1950/50852/26281/10818/2261/2255/2066/27006/942/5527/5296/5156 80 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6806003 Regulation of TP53 Expression and Degradation 36/4699 37/10654 3.127599242645536e-12 1.7220193477154246e-11 6.997559502637279e-12 11200/472/639/4194/8900/2475/5518/51230/7314/5515/6446/117584/890/983/5519/10000/900/7157/6233/7874/253260/5170/1029/80196/64223/1616/208/79109/7311/5516/1017/207/7316/9099/5527/4193 36 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 39/4699 41/10654 3.3533210685944485e-12 1.8390870235572678e-11 7.4732731051734835e-012 23165/348995/57122/23511/81608/23279/23225/9972/8021/55746/53981/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10898/10482/51692/8086/22916/81929/9631/29894/79023/23636/4686/8189/53371/9688/10189/8480/55339 39 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-418597 G alpha (z) signalling events 44/4699 48/10654 4.215398803164304e-12 2.302887128265635e-11 9.357960890088277e-12 2788/5579/2770/5578/5582/5583/107/2782/2773/2787/10681/112/111/2792/5588/2785/2783/2784/2771/5580/196883/115/2791/2781/150/113/10287/8601/2786/109/151/54331/59345/51764/94235/114/108/55970/2778/346562/152/2793/5581/2790 44 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-199418 Negative regulation of the PI3K/AKT network 84/4699 110/10654 4.542830507308622e-12 2.472144973744692e-11 1.0045753304615559e-11 5295/374/3643/2250/5291/5526/3082/941/2064/2534/9965/2264/3630/3654/9542/2885/51135/8660/5518/2252/5879/5515/5290/3667/8823/90865/2065/3815/5594/8074/57761/2260/5528/2249/6714/2099/2248/5519/2247/10000/7409/2246/2251/3932/5781/940/930/2263/4233/8503/5159/29851/3084/5529/7189/208/10718/5293/1956/2549/5595/5516/5305/5525/8870/207/8817/4615/2100/2254/152831/1950/50852/26281/10818/2261/2255/5728/2066/27006/942/5527/5296/5156 84 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-451927 Interleukin-2 family signaling 41/4699 44/10654 5.959215017251526e-12 3.2056466989353035e-11 1.3026394593064437e-11 5295/5777/1437/5291/6776/84868/3558/3717/3563/2885/9846/3600/3635/5290/1439/50615/3718/3567/3932/6777/59067/3562/6464/6775/1438/3581/6774/6850/6772/8503/3636/6654/3716/5293/2185/3561/3578/3568/3560/5296/3559 41 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69231 Cyclin D associated events in G1 41/4699 44/10654 5.959215017251526e-12 3.2056466989353035e-11 1.3026394593064437e-11 8454/5925/1869/5753/1031/3717/5520/28227/1030/5518/7314/5515/25/7027/5934/6714/5519/6502/595/896/6233/1163/1019/1029/4331/4067/1874/1870/7311/5516/894/902/1027/6500/7316/1026/5933/1871/1021/1022/1028 41 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69236 G1 Phase 41/4699 44/10654 5.959215017251526e-12 3.2056466989353035e-11 1.3026394593064437e-11 8454/5925/1869/5753/1031/3717/5520/28227/1030/5518/7314/5515/25/7027/5934/6714/5519/6502/595/896/6233/1163/1019/1029/4331/4067/1874/1870/7311/5516/894/902/1027/6500/7316/1026/5933/1871/1021/1022/1028 41 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6804757 Regulation of TP53 Degradation 35/4699 36/10654 6.931831263159206e-12 3.714614921173865e-11 1.5094626535284415e-11 11200/472/4194/8900/2475/5518/51230/7314/5515/6446/117584/890/983/5519/10000/900/7157/6233/7874/253260/5170/1029/80196/64223/1616/208/79109/7311/5516/1017/207/7316/9099/5527/4193 35 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5675221 Negative regulation of MAPK pathway 38/4699 40/10654 7.2710050295677686e-12 3.881555536697014e-11 1.577300270572636e-11 4893/1844/1850/1848/5526/1852/5605/5037/5894/1847/5518/4140/3845/3265/7314/5515/8844/1849/5594/5528/5519/80824/6233/1843/369/1846/11221/673/5529/7311/5536/7529/5595/5516/5604/5525/7316/5527 38 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-111885 Opioid Signalling 72/4699 91/10654 7.525716265701374e-12 4.0023127413048215e-11 1.6263708995255763e-11 2788/2770/817/5578/5582/2775/5530/107/4988/2782/5499/5518/814/2773/5515/2787/818/84152/5567/5594/10681/5142/112/5573/5528/111/5443/2792/5519/2785/2783/2784/5613/2771/5580/196883/115/801/2791/3838/2781/5568/113/5566/816/2786/5577/1020/5141/109/5516/5533/815/5321/54331/5575/59345/5532/51764/94235/114/108/5173/55970/10768/346562/2793/5576/5534/1385/5144/2790 72 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-4570464 SUMOylation of RNA binding proteins 43/4699 47/10654 8.8174678021975785e-012 4.6715942619944906e-11 1.89833864897362e-11 1912/23165/6045/80012/348995/6613/57122/23511/3190/1911/23279/23225/57332/9972/8021/55746/51602/10762/79902/9883/84733/6396/129401/7703/6015/4928/5903/55706/7175/8535/4927/8086/7329/648/81929/9631/79023/23636/3183/53371/9688/7341/8480 43 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 31/4699 31/10654 9.019420086414707e-12 4.742796180272003e-11 1.9272721020448537e-11 3725/9252/1848/1432/6196/5518/1386/6197/51231/5515/5601/1849/5594/5528/9261/5519/5598/4208/6195/2353/5600/1846/5602/5595/5516/1845/4205/466/2002/1385/5599 31 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 31/4699 31/10654 9.019420086414707e-12 4.742796180272003e-11 1.9272721020448537e-11 857/7478/5526/1452/324/8312/1855/5518/5515/2535/1856/7471/5528/89780/5519/2932/8321/1857/4040/7479/7855/10023/4041/23401/5529/5516/1499/5525/139285/1455/5527 31 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 70/4699 88/10654 9.238042701549175e-12 4.839631325736956e-11 1.966621816276376e-11 8454/7531/11190/203068/54801/79441/5116/5048/8655/6790/7846/11064/5518/55835/23332/93323/7314/8945/4659/1454/983/10540/6233/54930/54820/1453/9793/5500/22981/7532/84962/10382/121441/7277/9133/23354/891/9738/1639/4957/5566/7283/22919/79866/1069/5577/7311/10383/5347/80184/22897/4660/1778/115106/22995/55559/10142/95681/6500/1781/7316/10121/84131/23291/3320/10733/4751/9662/55142/8481 70 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-72312 rRNA processing 138/4699 205/10654 1.1468596553887942e-11 5.985839985746718e-11 2.432392616790165e-11 6158/5393/6138/6227/6206/6234/6191/6128/6132/6129/23404/55226/6176/10528/84135/27043/6224/6146/6154/6202/51096/6169/55272/6175/6218/28987/23481/6192/6156/117246/6143/6139/23160/26168/11340/3921/6208/6170/22984/10813/60528/9136/6203/6147/6222/1454/56902/51602/6134/6155/6231/6142/23521/10171/5822/6207/10969/6233/6188/79707/1453/4691/23016/118460/200916/6122/6230/2091/55651/55127/6194/3028/8780/9277/6136/6125/4839/6232/90459/6160/6193/10200/6210/6229/6205/11056/9790/140801/6181/55759/705/7311/6223/25873/51010/26354/56915/51202/9045/6187/6168/6157/6137/22894/84946/6144/9349/55813/4736/22803/51121/25879/6217/81887/6152/57050/51065/6141/55781/54931/6209/11224/6165/6130/6204/1736/6228/51013/6124/83732/27341/6189/6135/6201/6161/54512/6133/9188 138 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-109606 Intrinsic Pathway for Apoptosis 47/4699 53/10654 1.3645742741652653e-11 7.09578622565938e-11 2.8834279009652006e-11 7531/10971/7533/2810/1869/8655/836/840/7159/637/578/23368/7027/5594/841/7534/4836/22900/598/10000/708/3002/7157/331/57099/317/140735/1029/572/7532/6774/5366/8626/208/7161/7529/5595/5533/27113/596/10018/842/207/54205/5534/581/5599 47 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5358346 Hedgehog ligand biogenesis 55/4699 65/10654 1.5189511727359174e-11 7.869400171665048e-11 3.197791942601932e-11 5689/5682/143471/5705/5709/5695/3549/5711/5683/5699/5702/6868/6469/5696/5691/7314/5718/5700/122706/5707/23198/50846/9861/5698/5692/5713/5710/5719/6233/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721/5034 55 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-170834 Signaling by TGF-beta Receptor Complex 60/4699 73/10654 2.168312155352159e-11 1.1192317154832468e-10 4.548085093656618e-11 892/7321/4738/8239/9612/4609/4089/22938/23327/4088/5499/1030/9110/7040/904/7314/5054/7027/6497/51592/50848/7323/6667/4092/11171/7050/7046/5494/9958/9040/6233/7514/1025/57530/5500/4221/5590/3726/5501/1024/23645/8812/1874/142/905/4087/7048/7311/387/57154/51377/10273/64750/54778/7316/9611/5933/867/3065/6498 60 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-194138 Signaling by VEGF 81/4699 107/10654 2.4171754434330274e-11 1.2431187994798428e-10 5.0515098914235625e-11 5295/4893/857/5335/71/5579/5291/5578/1432/2534/9475/3690/5603/2475/6093/8440/3845/3265/3071/8877/5062/5829/5879/26999/5290/5567/10006/57761/5921/1500/9261/6714/10810/10000/3728/5580/7409/23191/3685/3791/1535/5600/6300/801/10787/253260/5170/5590/653361/5747/5568/3315/10152/7867/64223/5566/1003/10163/55845/5063/998/208/79109/2185/387/60/5058/558/1495/1499/4690/207/7422/10458/9047/10768/8936/3320/4846/1398/5296 81 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8943724 Regulation of PTEN gene transcription 52/4699 61/10654 3.081308591669309e-11 1.5788895119356606e-10 6.415940286918039e-11 1912/3725/6591/1822/9112/6045/80012/1911/5928/23512/57332/1107/2475/1386/23186/2146/51564/5594/84232/7101/84733/57459/3066/7157/8726/57521/6015/28956/9219/8535/5931/1108/2122/64223/10014/54815/55004/57504/648/23466/53615/5595/8841/5468/5978/57167/1958/8649/6615/3065/23028/10542 52 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-3232142 SUMOylation of ubiquitinylation proteins 36/4699 38/10654 3.40444642382185e-11 1.731827093857202e-10 7.037414041614963e-11 23165/348995/57122/23511/23279/23225/7428/5371/9972/8021/55746/51588/10762/79902/9883/9063/6396/129401/8554/4928/5903/55706/7175/4927/8086/7329/81929/9631/79023/23636/53371/9688/7341/5987/8480/4193 36 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5696394 DNA Damage Recognition in GG-NER 36/4699 38/10654 3.40444642382185e-11 1.731827093857202e-10 7.037414041614963e-11 10445/9978/10980/10987/7314/83444/86/1643/29844/10920/54891/6233/93973/8607/5886/8451/8450/1642/142/1069/2873/7311/60/8533/51138/7528/9318/7316/64708/283899/4798/79913/54617/5887/50813/7508 36 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654743 Signaling by FGFR4 38/4699 41/10654 5.6895001868563303e-11 2.8837755459733893e-10 1.1718446138233447e-10 5295/4893/5335/8569/9965/2264/2885/5518/3845/3265/7314/5515/5290/8823/5594/8074/2249/6714/2247/6233/2246/2251/5781/6464/673/6654/7311/2549/5595/5516/10253/8817/2254/7316/152831/26281/10818/867 38 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5685938 HDR through Single Strand Annealing (SSA) 35/4699 37/10654 7.350589162214783e-11 3.7123119366005593e-10 1.508526817841883e-10 83990/9156/1763/7486/5982/472/4683/84126/2067/672/6117/83695/6118/25/5888/116028/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/5983/5893/5883/10111/545/5932/7156 35 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-163359 Glucagon signaling in metabolic regulation 32/4699 33/10654 7.50663164114905e-11 3.777530761352425e-10 1.5350289943417411e-10 2788/107/2782/2787/5567/112/5573/111/2785/2783/2784/196883/115/2791/5568/113/5566/2641/2786/5577/109/54331/5575/59345/51764/94235/114/108/55970/2778/5576/2790 32 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 40/4699 44/10654 7.97180511928644e-11 3.997290852670772e-10 1.6243302160350568e-10 834/79370/55367/472/1387/51499/7159/637/27166/23368/332/64065/8797/7157/604/63970/839/317/5875/55240/5366/84883/147923/843/94241/8626/7161/10397/8795/665/27113/9540/8793/58484/3486/355/8794/124446/5876/581 40 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-350054 Notch-HLH transcription pathway 28/4699 28/10654 1.0622208102159469e-10 5.30732390584765e-10 2.156672332410726e-10 79718/9759/9612/22938/1387/6907/4853/9794/79885/2648/9734/55869/51564/55534/84441/10013/83933/4854/8850/3066/10046/10014/4855/4851/8841/9611/3065/3516 28 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-176033 Interactions of Vpr with host cellular proteins 34/4699 36/10654 1.5846095728497012e-10 7.861455266010532e-10 3.194563468419335e-10 23165/348995/57122/23511/292/23279/23225/3836/9972/8021/55746/10762/79902/11168/9883/6396/129401/4928/5903/55706/7175/293/4927/8086/81929/9631/3159/79023/23636/53371/9688/8815/8480/291 34 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-177243 Interactions of Rev with host cellular proteins 34/4699 36/10654 1.5846095728497012e-10 7.861455266010532e-10 3.194563468419335e-10 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/5902/7514/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/1104/5905/3837/81929/9631/79023/23636/53371/9688/8480 34 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2408522 Selenoamino acid metabolism 86/4699 118/10654 1.813161987601557e-10 8.963659966875304e-10 3.6424529180135067e-10 6158/6138/6227/6206/6234/6191/6128/6132/6129/9255/6176/6224/6146/6154/6202/6169/1491/6175/6218/6192/6156/6143/6139/3921/6208/6170/7296/6203/6147/4143/191/6222/2936/6134/6155/6231/6142/9061/23521/6207/6233/51091/6188/200916/6122/6230/6194/6136/6125/6232/6160/6193/6210/6229/6205/140801/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6217/6152/51065/6141/6209/11224/6165/6130/6204/6228/7965/6124/6189/6135/6201/6161/6133 86 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-912526 Interleukin receptor SHC signaling 27/4699 27/10654 2.416143097209946e-10 1.1902683889413208e-9 4.83674813919775e-10 5295/5777/1437/5291/3558/3717/3563/2885/9846/3635/5290/1439/3718/3567/3562/6464/1438/8503/3636/6654/3716/5293/3561/3568/3560/5296/3559 27 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 36/4699 39/10654 2.536446808329369e-10 1.2451647968162357e-9 5.059823960671763e-10 9134/10528/10576/10574/6468/10564/54461/10693/8877/10575/898/10517/26985/26190/10238/7157/83752/26224/8237/6774/26272/26270/55135/22948/84261/10694/8841/22803/7203/908/11328/6950/3801/55294/6499/26234 36 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 33/4699 35/10654 3.410453631826374e-10 1.6622323491736022e-9 6.754610385755679e-10 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/7884/4927/10482/8086/22916/81929/9631/79023/23636/4686/53371/9688/10189/8480 33 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 33/4699 35/10654 3.410453631826374e-10 1.6622323491736022e-9 6.754610385755679e-10 23165/91754/348995/57122/23511/23279/23225/9972/8021/55746/10762/983/79902/9883/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/81929/9631/140609/10783/79023/23636/53371/9688/8480 33 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-168253 Host Interactions with Influenza Factors 38/4699 42/10654 3.4215466446664604e-10 1.6622323491736022e-9 6.754610385755679e-10 3839/23165/348995/57122/23511/23279/23225/3836/9972/8021/7040/55746/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/293/4927/10898/3840/8086/3837/81929/9631/79023/23636/53371/9688/8480 38 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-74751 Insulin receptor signalling cascade 46/4699 54/10654 4.612451285757977e-10 2.233062622484207e-9 9.074223582144551e-10 5295/3643/4893/2250/5291/9965/2264/3630/2885/8660/9846/2252/3845/3265/54106/5290/3667/8823/5594/8074/57761/2260/2249/2248/2247/2246/2251/5781/30849/5170/6464/2263/208/6654/2549/5595/8817/2254/152831/26281/10818/2261/2255/27006/5296/2887 46 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-420499 Class C/3 (Metabotropic glutamate/pheromone receptors) 35/4699 38/10654 5.338892111013231e-10 2.575877843251744e-9 1.046727988485864e-9 50833/5726/2550/50832/259294/2912/259295/9568/2914/259296/259289/50835/338398/2916/259293/54429/80835/50840/2913/2918/50838/83756/259286/259287/50836/846/259290/80834/259292/50834/259285/2917/50831/50839/50837 35 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-159227 Transport of the SLBP independent Mature mRNA 32/4699 34/10654 7.327470106496614e-10 3.4873789930580494e-9 1.4171235674294971e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10482/8086/22916/81929/9631/79023/23636/4686/53371/9688/10189/8480 32 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-165054 Rev-mediated nuclear export of HIV RNA 32/4699 34/10654 7.327470106496614e-10 3.4873789930580494e-9 1.4171235674294971e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/5902/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/1104/5905/81929/9631/79023/23636/53371/9688/8480 32 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-4085377 SUMOylation of SUMOylation proteins 32/4699 34/10654 7.327470106496614e-10 3.4873789930580494e-9 1.4171235674294971e-9 23165/348995/6613/57122/23511/23279/23225/9972/8021/55746/51588/10762/79902/9883/6396/129401/4928/5903/55706/7175/10210/4927/8086/7329/81929/9631/79023/23636/53371/9688/7341/8480 32 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654727 Negative regulation of FGFR2 signaling 32/4699 34/10654 7.327470106496614e-10 3.4873789930580494e-9 1.4171235674294971e-9 2250/8569/2885/5518/2252/7314/5515/8823/5594/8074/2249/6714/2248/2247/6233/2246/2251/5781/673/2263/7311/5595/5516/10253/8817/2254/7316/26281/10818/867/2255/27006 32 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 29/4699 30/10654 8.05630261592638e-10 3.821300294851566e-9 1.55281508457756e-9 11065/7321/65264/8239/55236/3093/7347/7328/7332/7314/90268/10477/92912/29089/7324/6233/7874/7326/7317/7327/7311/997/7319/7320/7316/54926/7322/55284/27338 29 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 39/4699 44/10654 8.332611139929925e-10 3.939052538875964e-9 1.6006646244345275e-9 892/7321/8239/9612/4609/4089/22938/23327/4088/1030/904/7314/5054/7027/6497/51592/7323/6667/4092/7050/5494/6233/1025/4221/3726/1024/8812/1874/142/905/4087/7311/64750/54778/7316/9611/5933/3065/6498 39 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2428924 IGF1R signaling cascade 45/4699 53/10654 8.978639412716904e-10 4.23020460921293e-9 1.7189765318589057e-9 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/3845/3265/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/8471/2246/2251/5781/30849/5170/6464/2263/3481/208/6654/2549/3480/8817/2254/152831/26281/10818/2261/2255/27006/3479/5296 45 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 59/4699 75/10654 9.120076816358115e-10 4.281494857618669e-9 1.739818723068915e-9 5295/374/2250/5291/3082/941/2064/2534/9965/2264/9542/2885/8660/2252/5879/5290/3667/8823/2065/3815/8074/2260/2249/6714/2099/2248/2247/7409/2246/2251/3932/5781/940/930/2263/4233/8503/5159/29851/3084/10718/5293/1956/2549/8817/2100/2254/152831/1950/50852/26281/10818/2261/2255/2066/27006/942/5296/5156 59 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5685942 HDR through Homologous Recombination (HRR) 54/4699 67/10654 9.148493285509975e-10 4.281494857618669e-9 1.739818723068915e-9 83990/9156/1763/7486/5982/472/80198/4683/84126/672/6117/10714/83695/7314/6118/5888/116028/7517/84464/5985/5984/6233/5884/5810/5424/80010/54107/580/11073/5425/641/5111/6119/3364/10524/5427/144715/1111/79728/51426/146956/7311/5983/56655/51750/5883/10111/675/545/7316/10635/5932/7156/5981 54 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 25/4699 25/10654 1.2496319362015561e-9 5.809547147109221e-9 2.3607546511719883e-9 11065/7321/8697/51529/29945/51434/9184/29882/7314/996/51433/119504/7324/64682/6233/246184/8881/10393/7311/25906/991/7316/4085/4751/701 25 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 25/4699 25/10654 1.2496319362015561e-9 5.809547147109221e-9 2.3607546511719883e-9 9252/1848/1432/6196/5518/6197/51231/5515/1849/5594/5528/9261/5519/5598/4208/6195/5600/1846/5595/5516/1845/4205/466/2002/1385 25 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-168276 NS1 Mediated Effects on Host Pathways 36/4699 40/10654 1.4541948239723272e-9 6.716083989661668e-9 2.7291329452666254e-9 3839/23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/4927/10898/3840/8086/3837/81929/9631/79023/23636/53371/9688/8480 36 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654741 Signaling by FGFR3 36/4699 40/10654 1.4541948239723272e-9 6.716083989661668e-9 2.7291329452666254e-9 5295/4893/2250/5335/8569/2885/5518/3845/3265/7314/5515/5290/8823/5594/8074/2249/6714/2247/6233/2246/5781/6464/673/6654/7311/2549/5595/5516/10253/8817/2254/7316/26281/10818/2261/867 36 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 31/4699 33/10654 1.5714730545228014e-9 7.117252156612946e-9 2.892150748901047e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/3303/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/3304/81929/9631/79023/23636/53371/9688/8480 31 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-180746 Nuclear import of Rev protein 31/4699 33/10654 1.5714730545228014e-9 7.117252156612946e-9 2.892150748901047e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/1104/3837/81929/9631/79023/23636/53371/9688/8480 31 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-180910 Vpr-mediated nuclear import of PICs 31/4699 33/10654 1.5714730545228014e-9 7.117252156612946e-9 2.892150748901047e-9 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/11168/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/3159/79023/23636/53371/9688/8815/8480 31 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1839126 FGFR2 mutant receptor activation 31/4699 33/10654 1.5714730545228014e-9 7.117252156612946e-9 2.892150748901047e-9 2250/5431/5435/5433/5439/2252/8823/8074/5438/2249/2248/2247/2246/2251/2963/5434/5436/2263/2962/5432/22916/5440/5430/8817/5441/2254/4686/26281/5437/2255/27006 31 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-389356 CD28 co-stimulation 31/4699 33/10654 1.5714730545228014e-9 7.117252156612946e-9 2.892150748901047e-9 5295/941/2534/2885/2475/5062/5879/1326/5290/57761/9020/6714/10000/7525/7409/3932/940/253260/5170/64223/8503/4067/5063/998/208/79109/5058/9402/207/942/5296 31 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9022692 Regulation of MECP2 expression and activity 31/4699 33/10654 1.5714730545228014e-9 7.117252156612946e-9 2.892150748901047e-9 2290/79718/817/9212/27327/28996/9612/6907/192669/4204/4343/814/818/3066/26523/801/3930/5566/816/25942/27161/815/8841/57690/192670/9611/2874/3064/3065/23112/1385 31 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 46/4699 55/10654 1.611447366851264e-9 7.274829913373552e-9 2.9561836954929265e-9 834/4790/7295/29108/1432/10628/5603/83737/3654/7334/1540/3551/7314/257397/8767/23118/841/8517/5970/7128/598/10454/6233/5600/6300/5608/4791/351/330/64127/3656/7189/3326/7311/114548/1147/596/6885/842/10392/10910/58484/7316/7335/22861/329 46 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 38/4699 43/10654 1.6858857347472657e-9 7.586485806362695e-9 3.0828274906647033e-9 2788/107/554/2782/2787/5567/10681/112/5573/111/2792/2785/2783/2784/196883/115/2791/5568/359/113/5566/2786/5577/109/54331/5575/59345/51764/94235/114/108/8766/55970/2778/2793/5576/551/2790 38 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2428928 IRS-related events triggered by IGF1R 44/4699 52/10654 1.7421045488655125e-9 7.78953753696554e-9 3.1653391400774655e-9 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/3845/3265/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/8471/2246/2251/5781/30849/5170/2263/3481/208/6654/2549/3480/8817/2254/152831/26281/10818/2261/2255/27006/3479/5296 44 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-72165 mRNA Splicing - Minor Pathway 44/4699 52/10654 1.7421045488655125e-9 7.78953753696554e-9 3.1653391400774655e-9 6633/6431/4904/51639/23450/5431/5435/5433/9416/23020/5439/9410/10907/10262/6432/83443/5438/9343/6636/2963/6635/5434/6632/24148/5436/6637/57819/2962/6426/5432/22916/23451/5440/5430/85437/11325/5441/10594/4686/5437/6634/6427/10992/6628 44 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-72086 mRNA Capping 28/4699 29/10654 1.7730270678031425e-9 7.90263493077972e-9 3.2112971453610803e-9 5431/5435/5433/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/4686/8731/5437/2968/1022 28 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5628897 TP53 Regulates Metabolic Genes 65/4699 86/10654 2.5621214934438954e-9 1.1383603091124142e-8 4.625815621074589e-9 5563/7531/10971/9997/27327/7295/7533/2810/53632/7001/6341/192669/2475/4513/4343/7296/9377/1329/2936/51422/7249/27244/7534/10000/2877/54541/7157/1337/50484/26523/57521/28956/83667/7532/1345/84987/64223/5571/10128/25824/8626/208/55004/5562/4697/5564/5565/7248/7529/27161/27165/207/57690/192670/2539/54205/143686/1350/8649/5728/23112/10542/1349/1327/5052 65 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8854518 AURKA Activation by TPX2 57/4699 73/10654 2.9476871817465634e-9 1.3055371618839668e-8 5.305151759942347e-9 7531/11190/203068/54801/79441/5116/5048/8655/6790/7846/11064/5518/55835/23332/93323/1454/983/10540/54930/54820/1453/9793/22981/7532/10382/121441/7277/23354/9738/1639/4957/5566/7283/22919/1069/5577/10383/5347/80184/22897/1778/115106/22995/55559/10142/22974/3161/95681/1781/10121/84131/3320/10733/4751/9662/55142/8481 57 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 45/4699 54/10654 3.0809580047511135e-9 1.3580711800531876e-8 5.5186278271766965e-9 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/3845/3265/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/8471/2246/2251/5781/30849/5170/6464/2263/3481/208/6654/2549/3480/8817/2254/152831/26281/10818/2261/2255/27006/3479/5296 45 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5689880 Ub-specific processing proteases 140/4699 220/10654 3.0856460572433534e-9 1.3580711800531876e-8 5.5186278271766965e-9 5689/5682/79594/7419/10474/7375/9817/91833/6478/3091/143471/5705/11274/55031/8239/5709/5695/4792/11047/4609/4194/4089/5711/4088/5683/408/5699/8312/5702/8900/57599/377630/6881/51616/1540/80351/5696/5691/7314/5718/6314/90865/2648/5700/122706/5707/8737/55611/57646/23198/63967/8517/993/890/7417/4092/1643/9861/23586/81847/64426/7046/6502/5698/9146/5692/5713/5710/10454/7157/9958/8313/5719/6233/9804/23770/8607/7874/10600/51651/8237/4303/409/330/5706/27005/7416/25862/9738/8658/84132/5714/79589/27430/5688/9097/5687/5708/4087/63891/7189/5704/7311/367/5694/9960/23358/23032/5684/8295/5720/7186/6885/991/5690/2625/5717/9491/4086/1080/10197/64750/7316/10213/8678/9100/5715/5701/329/9099/5685/5686/5728/10868/5716/5693/154/10254/5721/4193 140 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2871796 FCERI mediated MAPK activation 30/4699 32/10654 3.3637677427065e-9 1.4666863076894178e-8 5.959993842912465e-9 3725/4893/5335/2885/3845/3265/5062/5879/5601/5336/5594/4214/7409/2353/6464/2205/3937/2206/6850/4067/5602/6654/5058/6416/5595/9402/27040/5609/5599/2207 30 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-381042 PERK regulates gene expression 30/4699 32/10654 3.3637677427065e-9 1.4666863076894178e-8 5.959993842912465e-9 5393/1965/23404/3576/3309/4801/6347/11340/468/1054/8894/9451/8570/23016/118460/1968/5073/1051/4800/22926/51010/56915/167227/22894/440/4802/1649/51013/467/54512 30 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-73863 RNA Polymerase I Transcription Termination 30/4699 32/10654 3.3637677427065e-9 1.4666863076894178e-8 5.959993842912465e-9 5435/2965/64425/2967/30834/404672/2068/9533/5434/9015/79101/221830/7270/4331/9013/2966/2071/10849/6908/5440/902/9014/25885/5441/51082/7343/5437/2968/84172/1022 30 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 37/4699 42/10654 3.400857821441783e-9 1.4782676103109172e-8 6.007055366535592e-9 83990/9156/1763/7486/5982/472/4683/84126/672/6117/83695/6118/5888/116028/7517/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/1111/79728/5983/5883/10111/675/545/10635/5932/7156 37 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 41/4699 48/10654 3.5528291587060286e-9 1.5395593021059456e-8 6.256118921438166e-9 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/8812/905/2071/5432/22916/6917/5440/902/5430/6749/5441/7469/4686/9150/5437/6827/2968/1022/8178 41 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-3899300 SUMOylation of transcription cofactors 39/4699 45/10654 3.580035661947291e-9 1.5465754059612298e-8 6.28462940494067e-9 1912/6045/80012/6613/28996/9612/1911/1387/57332/4152/115426/10499/6612/11315/3622/51588/1655/84733/10155/9063/7690/7703/6015/8554/8535/4869/10210/10521/1616/7329/25942/648/1487/8204/7341/2033/6294/8648/10891 39 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-75067 Processing of Capped Intronless Pre-mRNA 27/4699 28/10654 3.8972044846047675e-9 1.678427943676409e-8 6.820422443189486e-9 51585/81608/1477/53981/134353/11051/8106/1478/23283/6636/10914/6635/7884/84967/6637/10898/51692/22916/1479/79869/29894/4686/8189/10978/6634/55339/6628 27 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5619084 ABC transporter disorders 59/4699 77/10654 5.677381926773705e-9 2.4376282034221044e-8 9.905491724807173e-9 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/79139/91445/23198/9861/5698/215/5692/5713/5710/8647/5719/6233/6048/5706/19/335/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/1244/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 59 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-375276 Peptide ligand-binding receptors 129/4699 201/10654 5.928915958249892e-9 2.537865245543551e-8 1.0312812738676e-8 729230/2532/10316/2149/7852/1237/4987/51289/2150/6349/3576/6360/4985/2920/2921/1236/554/2831/5367/4988/6370/58191/6755/1524/643/185/339403/2847/2833/6347/187/6750/2587/6387/10663/4889/9283/727/1909/117579/3579/6375/2358/6846/5179/6367/8811/56923/2832/2826/6376/5443/6354/3627/6346/9034/51083/2829/1233/6366/2861/728/183/10022/6373/6357/6869/6361/2147/50865/10803/351/8484/6351/6863/6752/84539/6753/3577/5368/6754/8862/301/6751/186/10563/5540/256933/10850/624/4852/5473/4283/1910/10874/6356/56477/129521/1234/57007/283869/4986/6374/5539/2852/1230/4886/2919/5196/3827/5173/2357/6352/6348/1906/6364/5697/6288/6372/719/6363/2359/5660/1325/1232/551/4887/718/623 129 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-112409 RAF-independent MAPK1/3 activation 23/4699 23/10654 6.460012832360754e-9 2.7401383736055886e-8 1.1134765320844423e-8 1844/1850/1848/1852/5605/3717/1847/3569/3572/1849/5594/983/80824/1843/3570/7297/5781/8682/1846/11221/3716/5595/5604 23 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 23/4699 23/10654 6.460012832360754e-9 2.7401383736055886e-8 1.1134765320844423e-8 5431/5435/5433/5439/51497/5438/7936/6829/25920/2963/5434/5436/2962/5432/22916/5440/5430/5441/7469/4686/9150/5437/6827 23 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 23/4699 23/10654 6.460012832360754e-9 2.7401383736055886e-8 1.1134765320844423e-8 11065/7321/8697/51529/29945/51434/29882/7314/996/983/51433/119504/7324/64682/6233/246184/8881/891/10393/7311/25906/991/7316 23 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654736 Signaling by FGFR1 42/4699 50/10654 6.491303565785773e-9 2.7451175320371162e-8 1.1154998518249493e-8 5295/4893/2250/5335/8569/2885/5518/3845/3265/7314/5515/5290/5594/8074/2260/2249/6714/2248/2247/6233/2246/2251/200734/5781/6464/673/6654/7311/53834/2549/5595/5516/10253/8817/2254/7316/26281/10818/867/2255/27006/161742 42 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 40/4699 47/10654 6.93323540612847e-9 2.914449853354602e-8 1.1843093571136562e-8 8454/79718/892/3091/9978/9759/9612/4609/22938/1387/6907/9794/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/8850/3066/6233/10046/1024/10014/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 40 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-437239 Recycling pathway of L1 40/4699 47/10654 6.93323540612847e-9 2.914449853354602e-8 1.1843093571136562e-8 9252/71/7430/51807/347688/1785/10381/7846/1808/81027/6456/5962/163/6196/1759/6197/8986/161/5594/8650/6714/10376/6195/1213/1211/1175/1173/84617/10382/7277/4478/160/26052/27330/3897/10383/24137/60/84790/7280 40 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 29/4699 31/10654 7.185586702400077e-9 2.975977501524988e-8 1.2093115953115486e-8 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/3837/81929/9631/79023/23636/53371/9688/8480 29 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 29/4699 31/10654 7.185586702400077e-9 2.975977501524988e-8 1.2093115953115486e-8 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/81929/9631/79023/23636/53371/9688/8480 29 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 29/4699 31/10654 7.185586702400077e-9 2.975977501524988e-8 1.2093115953115486e-8 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/2646/79902/9883/2645/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/79023/23636/53371/9688/8480 29 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 29/4699 31/10654 7.185586702400077e-9 2.975977501524988e-8 1.2093115953115486e-8 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/2646/79902/9883/2645/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/79023/23636/53371/9688/8480 29 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654733 Negative regulation of FGFR4 signaling 29/4699 31/10654 7.185586702400077e-9 2.975977501524988e-8 1.2093115953115486e-8 8569/9965/2264/2885/5518/7314/5515/8823/5594/8074/2249/6714/2247/6233/2246/2251/5781/673/7311/5595/5516/10253/8817/2254/7316/152831/26281/10818/867 29 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 26/4699 27/10654 8.554894170300914e-9 3.5223083328746285e-8 1.4313173762318554e-8 5431/5435/5433/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/5440/902/5430/5441/8731/5437/2968/1022 26 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 26/4699 27/10654 8.554894170300914e-9 3.5223083328746285e-8 1.4313173762318554e-8 5431/5435/5433/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/5440/902/5430/5441/8731/5437/2968/1022 26 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF) 45/4699 55/10654 9.693755875300541e-9 3.979541885649696e-8 1.6171177852917493e-8 79718/10484/3638/5469/1387/6907/4801/9632/10499/23054/85441/31/96764/4598/5465/2222/6667/3156/6604/80205/51128/10654/6319/6721/10802/9453/4800/32/1595/5901/4047/9871/3837/4802/6720/2194/22937/1717/6256/10498/2224/3422/4520/8648/10427 45 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 64/4699 86/10654 9.892530012418114e-9 4.049303830155986e-8 1.6454660938255694e-8 5295/5335/71/51517/5291/4651/2268/10094/2534/8976/2885/3071/5879/26999/25/1072/5290/10093/10006/5336/4771/5594/4644/4641/6714/10810/7525/5580/7409/23191/10109/10787/2214/5747/2209/6850/10152/10092/10163/4067/55845/998/695/3326/10097/60/5058/5595/4690/4627/10458/919/3055/10552/10768/8936/917/3320/1398/10096/5296/5581/5338/10095 64 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8939211 ESR-mediated signaling 140/4699 223/10654 1.1251585105542326e-8 4.592216711680647e-8 1.8660829642606918e-8 5295/2788/374/3725/4893/857/7764/2770/27327/10274/5431/5435/5433/1509/5469/4609/1387/8312/2782/5439/192669/10499/1386/4343/3845/904/7392/3265/8877/2773/2787/6387/5290/4316/5594/10681/5481/5438/4313/865/1655/6667/2792/6714/2099/2494/8850/10000/2785/595/2783/2784/2771/7514/1025/2353/26523/801/2791/2957/5170/2963/3838/5434/5590/6464/5241/5747/5436/1903/3315/4318/200845/5885/2962/8503/10524/8243/4602/2786/208/3326/6908/1956/5536/3169/5432/3480/10728/5595/7528/3727/27161/2354/596/5440/54331/2309/59345/8204/5430/207/5451/2625/57690/6722/1027/51764/94235/5441/10735/192670/2100/1950/55970/4314/346562/2289/7391/2958/5437/2793/3320/2033/4846/9126/3065/2002/2066/861/23028/23112/10498/1385/5296/3276/8202/8648/2288/2790 140 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-167169 HIV Transcription Elongation 39/4699 46/10654 1.3481672821233966e-8 5.454832461386884e-8 2.2166135808004883e-8 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/7469/4686/9150/5437/6827/2968/1022/8178 39 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 39/4699 46/10654 1.3481672821233966e-8 5.454832461386884e-8 2.2166135808004883e-8 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/7469/4686/9150/5437/6827/2968/1022/8178 39 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 39/4699 46/10654 1.3481672821233966e-8 5.454832461386884e-8 2.2166135808004883e-8 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/7469/4686/9150/5437/6827/2968/1022/8178 39 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1433557 Signaling by SCF-KIT 37/4699 43/10654 1.3976519022724376e-8 5.6226454750444195e-8 2.2848057036092936e-8 5295/5777/4893/5578/6776/3717/2534/2885/9846/3845/3265/5879/5290/3815/9306/6714/7525/7409/3932/6777/5781/10019/4318/6774/6772/8651/8503/4067/1111/6654/7006/10750/9402/867/5296/10076/2887 37 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5696395 Formation of Incision Complex in GG-NER 37/4699 43/10654 1.3976519022724376e-8 5.6226454750444195e-8 2.2848057036092936e-8 6613/7507/9978/2965/2067/2967/6612/6117/7334/7314/6118/404672/1643/2068/6233/5886/8451/8554/8450/4331/2966/6119/1642/142/2071/1069/7329/7311/902/7336/54778/7316/7341/2968/5887/1022/7508 37 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-198753 ERK/MAPK targets 22/4699 22/10654 1.468523763815687e-8 5.874095055262748e-8 2.3869841954958838e-8 9252/1848/1432/6196/5518/6197/51231/5515/1849/5594/5528/5519/5598/4208/6195/5600/1846/5595/5516/1845/4205/2002 22 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-392170 ADP signalling through P2Y purinoceptor 12 22/4699 22/10654 1.468523763815687e-8 5.874095055262748e-8 2.3869841954958838e-8 2788/64805/2770/2782/2773/2787/10681/2792/2785/2783/2784/2771/2791/2786/54331/59345/51764/94235/55970/346562/2793/2790 22 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-447115 Interleukin-12 family signaling 46/4699 57/10654 1.5295290091825534e-8 6.040584726423891e-8 2.4546385677925844e-8 759/3593/5908/3313/6175/3717/3181/4001/3594/4282/5062/3572/1072/3592/6627/9049/27250/9987/3185/149233/3458/5478/302/51561/7297/6775/9446/3595/821/4478/6774/6772/998/6648/3716/2939/6888/246778/3586/829/6950/9466/6845/375/5721/5034 46 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 28/4699 30/10654 1.5316582354750038e-8 6.040584726423891e-8 2.4546385677925844e-8 56852/5982/9978/57599/6117/10714/7314/51514/6118/5985/5984/6233/5424/8451/54107/8450/5425/5111/6119/5427/1642/7311/5983/56655/7320/7316/7398/5981 28 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-114452 Activation of BH3-only proteins 28/4699 30/10654 1.5316582354750038e-8 6.040584726423891e-8 2.4546385677925844e-8 7531/10971/7533/2810/1869/8655/7159/637/23368/7027/7534/10000/7157/140735/572/7532/5366/8626/208/7161/7529/5533/27113/596/10018/207/5534/5599 28 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-4090294 SUMOylation of intracellular receptors 28/4699 30/10654 1.5316582354750038e-8 6.040584726423891e-8 2.4546385677925844e-8 7068/6613/7181/4929/9759/8856/7067/6612/5914/7421/10062/51588/2516/5465/2099/2494/9063/8554/5241/2908/9971/7329/367/6095/5468/7341/6256/7376 28 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 28/4699 30/10654 1.5316582354750038e-8 6.040584726423891e-8 2.4546385677925844e-8 7124/7375/10616/1540/3551/7314/257397/81858/8737/55072/23118/8517/7128/10454/6233/331/8717/330/27005/7311/1147/7186/56957/6885/7316/7132/329/9099 28 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-380259 Loss of Nlp from mitotic centrosomes 54/4699 70/10654 1.6649936475013916e-8 6.529751623161883e-8 2.6534153394464988e-8 7531/11190/203068/54801/79441/5116/5048/8655/7846/11064/5518/55835/23332/93323/1454/983/10540/54930/54820/1453/9793/22981/7532/10382/121441/7277/23354/9738/1639/4957/5566/7283/22919/1069/5577/10383/5347/80184/22897/1778/115106/22995/55559/10142/95681/1781/10121/84131/3320/10733/4751/9662/55142/8481 54 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 54/4699 70/10654 1.6649936475013916e-8 6.529751623161883e-8 2.6534153394464988e-8 7531/11190/203068/54801/79441/5116/5048/8655/7846/11064/5518/55835/23332/93323/1454/983/10540/54930/54820/1453/9793/22981/7532/10382/121441/7277/23354/9738/1639/4957/5566/7283/22919/1069/5577/10383/5347/80184/22897/1778/115106/22995/55559/10142/95681/1781/10121/84131/3320/10733/4751/9662/55142/8481 54 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9006931 Signaling by Nuclear Receptors 179/4699 299/10654 2.0447838002276358e-8 7.996870349636771e-8 3.2495904404731815e-8 5295/2788/5161/374/3725/4893/857/7764/79718/5160/2770/10901/27327/10274/5915/8644/5431/5435/5433/1509/5469/9612/4609/124/1387/6907/8312/2782/5439/192669/10499/1386/5914/4343/3845/904/1071/7392/3265/8877/216/2773/10062/2787/6387/5290/4316/5360/5594/10681/1737/5481/5438/348/4313/865/1655/6667/2792/6714/2099/2494/8850/10000/2785/595/2783/2784/2771/7514/1025/2353/6257/26523/801/29116/2791/2957/5105/5170/2963/3838/5434/5590/6464/112724/1374/5241/6319/5747/5436/1903/3315/4318/126/200845/5885/19/2962/8503/10524/2171/8243/4602/2786/208/3326/6908/1956/5536/3169/5432/3480/10728/5595/7528/3727/27161/2354/596/5440/8841/54331/347/2309/59345/8204/5430/207/5451/2625/57690/6722/1027/51764/94235/5441/10735/6720/192670/2100/1950/9611/55970/2874/2194/4314/127/346562/2289/7391/2958/5163/5437/2793/3320/2033/221656/4846/9126/3065/2002/2066/861/23028/6256/23112/7376/10498/1385/1738/5296/6258/3276/5916/8202/8648/2288/2790 179 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2559585 Oncogene Induced Senescence 30/4699 33/10654 2.1286714624543126e-8 8.255952301894627e-8 3.354870406078039e-8 2077/27327/5925/2114/1869/4194/1031/192669/1030/4343/7314/7027/5594/6667/7157/6233/26523/1019/1029/1870/7311/2113/5595/57690/192670/7316/1871/1021/23112/4193 30 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 30/4699 33/10654 2.1286714624543126e-8 8.255952301894627e-8 3.354870406078039e-8 4790/4792/177/3654/7334/3551/7314/257397/6283/8767/23118/8517/5970/10454/6233/4791/351/64127/3656/7189/7311/1147/6885/10392/7316/7335/4793/3146/6288/6285 30 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-68962 Activation of the pre-replicative complex 30/4699 33/10654 2.1286714624543126e-8 8.255952301894627e-8 3.354870406078039e-8 5422/4174/84515/4998/10926/990/55388/6117/5001/6118/23594/5557/4175/23649/4999/4172/5000/8318/54107/4173/51053/6119/5427/81620/23595/4176/56655/1017/8317/4171 30 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-112399 IRS-mediated signalling 40/4699 48/10654 2.3835266643240625e-8 9.193602848107098e-8 3.735891995557091e-8 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/3845/3265/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/2246/2251/5781/30849/5170/2263/208/6654/2549/8817/2254/152831/26281/10818/2261/2255/27006/5296 40 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-73893 DNA Damage Bypass 40/4699 48/10654 2.3835266643240625e-8 9.193602848107098e-8 3.735891995557091e-8 56852/5982/9978/25898/57599/6117/10714/7314/51514/6118/9636/11201/51455/5985/5984/6233/5424/8451/124739/54107/7706/8450/5425/5111/6119/5427/1642/9246/51426/7311/7318/5983/56655/7320/7316/9100/10459/7415/7398/5981 40 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-168638 NOD1/2 Signaling Pathway 32/4699 36/10654 2.5402290628225842e-8 9.744485257384995e-8 3.9597473455560566e-8 834/1432/5603/83737/3654/7334/1540/3551/7314/257397/8767/23118/841/8517/7128/10454/6233/5600/6300/5608/330/64127/3656/7189/7311/1147/6885/842/10392/7316/7335/329 32 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 32/4699 36/10654 2.5402290628225842e-8 9.744485257384995e-8 3.9597473455560566e-8 71/51517/10094/8976/2885/3071/5879/26999/25/10093/10006/5594/10810/23191/10109/10787/5747/10152/10092/10163/55845/998/695/10097/60/5595/4690/10458/10552/8936/10096/10095 32 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 34/4699 39/10654 2.738537019597748e-8 1.0476583039551058e-7 4.2572409712375726e-8 83990/9156/1763/7486/5982/472/4683/84126/672/6117/83695/6118/5888/116028/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/1111/5983/5883/10111/675/545/5932/7156 34 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 36/4699 42/10654 2.7468821936391815e-8 1.0479952717036442e-7 4.258610265882255e-8 2788/1459/2770/1460/2775/10576/1457/2782/10574/10693/2773/2787/10575/10681/2792/2785/2783/2784/2771/2791/2781/5082/2786/22948/10694/54331/59345/51764/94235/7203/908/55970/346562/2793/6950/2790 36 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654732 Negative regulation of FGFR3 signaling 27/4699 29/10654 3.2573599611427145e-8 1.2393857413128378e-7 5.036340319324922e-8 2250/8569/2885/5518/7314/5515/8823/5594/8074/2249/6714/2247/6233/2246/5781/673/7311/5595/5516/10253/8817/2254/7316/26281/10818/2261/867 27 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-389513 CTLA4 inhibitory signaling 21/4699 21/10654 3.3379250065524104e-8 1.263193183072664e-7 5.1330837098919184e-8 5526/941/2534/5518/5515/5528/6714/5519/10000/7525/3932/5781/1493/4067/5529/208/5516/5525/207/942/5527 21 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5621575 CD209 (DC-SIGN) signaling 21/4699 21/10654 3.3379250065524104e-8 1.263193183072664e-7 5.1330837098919184e-8 9252/4893/4790/1387/2534/3385/5894/3845/3265/5062/5567/5970/5568/3384/5566/4067/5063/30835/5971/5058/2033 21 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 48/4699 61/10654 3.401070016827136e-8 1.2836296515121772e-7 5.216128888286101e-8 71/51517/4651/10094/8976/2885/3071/5879/26999/25/1072/10093/10006/4771/5594/4644/4641/10810/7409/23191/10109/10787/2214/5747/2209/6850/10152/10092/10163/55845/998/695/3326/10097/60/5058/5595/4690/4627/10458/919/10552/8936/917/3320/1398/10096/10095 48 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1227986 Signaling by ERBB2 41/4699 50/10654 3.9664568530564126e-8 1.493004134501663e-7 6.06693837831685e-8 5295/4893/5335/26469/5578/2064/5753/2534/4145/9542/2885/3845/3265/7314/5290/2065/6714/10000/6233/7525/5580/6464/5782/10193/3084/208/6654/10718/7311/387/1956/2549/11140/8065/10273/207/7316/1950/3320/2066/5581 41 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-163125 Post-translational modification: synthesis of GPI-anchored proteins 67/4699 93/10654 4.021067312503644e-8 1.5095129697206195e-7 6.134023313754505e-8 116372/146183/146760/10026/419/154064/123904/51604/7512/93183/2813/7007/8875/55350/22854/4062/83639/353091/248/4045/4061/7070/54742/27076/137797/2350/338328/6975/249/8813/8000/23627/5067/80328/135228/349667/1048/2215/53942/1087/420/161357/349633/58530/8434/503542/646627/10942/84628/284348/2822/171169/683/1368/130576/152330/8876/4978/147719/50863/10232/51299/8581/1043/257194/266727/80740 67 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-194315 Signaling by Rho GTPases 257/4699 455/10654 4.0754404600194634e-8 1.5244936833911324e-7 6.194898608471989e-8 55839/11130/71/6249/51517/5579/57522/392/9735/7531/5526/29/51807/10811/10971/5578/9212/347688/613/1894/388/7533/2810/147841/348995/54509/10381/57122/6280/1780/23122/5048/57405/8655/10094/23279/1432/2017/2491/9138/7846/79784/9475/1060/9322/397/81027/4628/51291/11004/8976/1855/2885/6093/9184/8997/8826/10499/5518/8874/23332/25909/3071/10726/81930/5062/55746/9411/2665/5879/5515/9181/26999/25/79682/64333/1072/10403/4638/25936/4659/10093/1856/10006/4771/389/5594/29127/3619/64105/7534/332/5528/6453/9828/6714/79902/3796/5519/81565/999/89953/396/10810/85360/91687/11243/10376/23002/57584/11113/58504/83540/5580/7409/1857/9055/23191/7514/54820/6396/1535/5600/91614/801/64946/9793/30849/10109/5586/140735/9886/5500/10787/4221/3831/220134/5170/84617/4928/5590/5903/9912/653361/55055/5747/80776/1783/401541/64411/2316/7532/3633/10382/7074/10627/79172/7277/79980/6232/5501/50650/10152/6279/54821/10092/9183/10163/1062/699/94134/22919/55845/5063/3895/57514/5529/51143/998/695/10788/6654/10097/57120/367/10383/5347/387/60/84790/84643/5058/4660/7280/4629/7529/5595/1778/5516/5905/81929/54908/55143/1495/1499/5525/4690/1058/991/79019/4627/10928/348235/80152/10458/1063/6722/8379/1027/9459/1080/23421/55920/79023/6242/1781/10398/4085/5585/5216/10552/81624/55166/50649/8936/4637/51466/995/79003/23028/89941/2/90627/5527/10096/701/23380/9928/29941/3799/103910/57551/5296/5300/10095/4952/9901 257 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 24/4699 25/10654 4.104406070668433e-8 1.5244936833911324e-7 6.194898608471989e-8 2308/2475/84335/7249/2932/10000/2931/253260/5170/572/4303/6199/64223/208/79109/1147/2309/842/207/1027/1026/3164/1385/4193 24 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 24/4699 25/10654 4.104406070668433e-8 1.5244936833911324e-7 6.194898608471989e-8 51400/5520/8900/28227/5518/7465/5515/993/890/983/5519/7514/2305/9133/891/4331/5347/5516/1017/994/902/9088/995/1022 24 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 24/4699 25/10654 4.104406070668433e-8 1.5244936833911324e-7 6.194898608471989e-8 3107/10484/811/567/3106/51752/3309/9632/3133/6892/22872/10134/51128/6396/3135/10802/6890/821/2923/9871/3105/6891/3134/10427 24 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5673000 RAF activation 29/4699 32/10654 4.4129836646104926e-8 1.634783394488953e-7 6.643069424299089e-8 4893/5526/817/5605/3717/4296/5894/5518/4140/3845/3265/5515/818/8844/5528/6714/5519/369/801/673/5529/816/7529/5516/815/5604/5525/5527/5245 29 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8953750 Transcriptional Regulation by E2F6 31/4699 35/10654 5.1525743504128965e-8 1.9037406284157122e-7 7.735998055190554e-8 80314/6045/80012/79813/11335/1869/1911/5928/10138/23512/672/6241/5888/83746/7027/2146/1876/8726/7703/317/23429/6015/84108/5931/1111/648/23468/8317/4149/5932/10919 31 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 44/4699 55/10654 5.192048341602644e-8 1.9132902550157775e-7 7.774803705342266e-8 51807/347688/10381/1780/3305/8655/832/7846/81027/3306/3312/3303/3337/10376/3301/10540/140735/84617/5241/1783/10382/10294/55860/830/7277/1639/2908/51143/3326/367/10383/84790/3304/7280/10728/829/1778/1781/2289/10121/3320/10963/55466/2288 44 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5696400 Dual Incision in GG-NER 35/4699 41/10654 5.378228405103939e-8 1.9767101258549555e-7 8.032515281251957e-8 5982/7507/9978/2965/2067/2967/6117/10714/7314/6118/404672/1643/5985/2068/5984/6233/5424/8451/54107/8450/5425/5111/2966/6119/5427/1642/142/2071/51426/7311/5983/56655/7316/2968/5981 35 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5655302 Signaling by FGFR1 in disease 33/4699 38/10654 5.451005149165266e-8 1.998227475046484e-7 8.119952702618042e-8 5295/4893/11052/2250/5335/9530/613/6776/11064/2885/9846/3845/3265/7750/8805/26127/5290/8074/2260/2249/399687/2247/2246/2251/6777/6774/6772/6654/11160/2549/2254/26281/10818 33 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-383280 Nuclear Receptor transcription pathway 42/4699 52/10654 6.273909824153194e-8 2.2938982794560114e-7 9.321434004087256e-8 3174/7068/5915/8013/6097/7181/4929/5469/2104/9612/8856/29959/2101/7067/5914/8431/7421/10062/7025/2516/5465/2099/7101/2494/2103/6257/5241/7182/3172/2063/2908/9971/367/6095/5468/2100/9611/3164/6256/7376/6258/5916 42 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-202040 G-protein activation 26/4699 28/10654 6.910486008435056e-8 2.5200837287903424e-7 1.0240556162875738e-7 2788/2770/2775/4988/2782/2773/2787/10681/5443/2792/2785/2783/2784/2771/2791/2781/2786/54331/59345/51764/94235/5173/55970/346562/2793/2790 26 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 20/4699 20/10654 7.586128343594412e-8 2.738026785194487e-7 1.1126184717164582e-7 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 20/4699 20/10654 7.586128343594412e-8 2.738026785194487e-7 1.1126184717164582e-7 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-164938 Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 20/4699 20/10654 7.586128343594412e-8 2.738026785194487e-7 1.1126184717164582e-7 162/1174/567/163/55690/51606/161/10053/926/3932/1175/8907/940/1173/160/920/8905/164/130340/375 20 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8964616 G beta:gamma signalling through CDC42 20/4699 20/10654 7.586128343594412e-8 2.738026785194487e-7 1.1126184717164582e-7 2788/2782/2787/10681/2792/2785/2783/2784/2791/998/2786/5058/54331/59345/9459/51764/94235/55970/2793/2790 20 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 67/4699 94/10654 7.984919263685105e-8 2.874570934926638e-7 1.1681042485606822e-7 10844/7531/11190/203068/54801/51807/347688/79441/10381/5116/5048/8655/7846/11064/81027/5518/55835/23332/93323/1454/983/80097/10376/10540/54930/54820/1453/27229/9793/84617/22981/7532/10382/121441/7277/23354/9738/1639/4957/5566/7283/22919/10426/1069/5577/10383/5347/84790/80184/22897/7280/1778/115106/4926/22995/55559/10142/95681/1781/10121/84131/3320/10733/4751/9662/55142/8481 67 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8986944 Transcriptional Regulation by MECP2 48/4699 62/10654 8.615813739944343e-8 3.0937602278470223e-7 1.2571735218871541e-7 627/2290/79718/5770/817/9212/27327/6657/28996/9612/4988/6907/192669/4204/3654/4343/6750/814/818/6446/54487/4208/3066/26523/801/2891/2904/3930/4233/5566/1392/816/25942/27161/815/8841/5468/4986/57690/192670/9611/2874/2289/3064/5728/3065/23112/1385 48 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-3371571 HSF1-dependent transactivation 23/4699 24/10654 8.968789897517818e-8 3.1878939281303837e-7 1.295425482865998e-7 817/3305/1387/2475/3306/3312/818/3303/84335/3337/3297/57521/1410/64223/26353/816/3326/3304/10728/815/3320/2033/2288 23 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-450302 activated TAK1 mediates p38 MAPK activation 23/4699 24/10654 8.968789897517818e-8 3.1878939281303837e-7 1.295425482865998e-7 1432/3654/7334/7314/257397/5606/8767/23118/8517/9261/10454/6233/5600/5608/7867/64127/3656/7189/7311/6885/10392/7316/7335 23 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5260271 Diseases of Immune System 23/4699 24/10654 8.968789897517818e-8 3.1878939281303837e-7 1.295425482865998e-7 4790/10333/4792/929/51135/7187/3551/8517/5970/7096/4791/81793/7098/695/81622/23643/1147/7099/4615/7100/114609/7097/148022 23 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5602358 Diseases associated with the TLR signaling cascade 23/4699 24/10654 8.968789897517818e-8 3.1878939281303837e-7 1.295425482865998e-7 4790/10333/4792/929/51135/7187/3551/8517/5970/7096/4791/81793/7098/695/81622/23643/1147/7099/4615/7100/114609/7097/148022 23 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5620912 Anchoring of the basal body to the plasma membrane 69/4699 98/10654 1.1230243367046703e-7 3.981631739225649e-7 1.6179670135404874e-7 79867/7531/11190/203068/54801/85302/79441/5116/5048/22832/8655/7846/11064/5518/55835/23332/93323/1454/91147/983/10540/54930/54820/23322/1453/9793/22981/54903/80776/7532/10382/121441/7277/23354/146057/9738/1639/4957/5566/7283/22919/4867/1069/5577/10383/5347/80184/22897/9657/1778/115106/22995/55559/10142/95681/1781/8766/79598/10121/84131/3320/79600/10733/4751/26123/9662/55142/8481/51259 69 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-438064 Post NMDA receptor activation events 59/4699 81/10654 1.3712176288763204e-7 4.849343957033637e-7 1.9705686195173425e-7 5563/4893/51807/817/347688/53632/10381/107/7846/81027/6196/1740/8874/6197/3845/3265/814/5879/5923/818/5567/5594/51422/5573/6714/10376/6195/5613/801/2891/5170/84617/3838/2904/10382/5568/7277/5566/5571/27330/3084/816/5577/5562/10383/84790/5564/5565/7280/5595/815/28964/5575/114/5576/4137/2066/1385/8536 59 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-432722 Golgi Associated Vesicle Biogenesis 44/4699 56/10654 1.3875107603554654e-7 4.894635948590637e-7 1.9889733724217465e-7 162/1176/5286/1174/1785/8546/7037/3482/408/6456/3312/25977/10618/10053/55330/8301/2495/388552/6844/1213/2580/1211/23431/8907/84062/9685/9026/8775/9829/8905/51429/8673/2512/164/130340/6272/7163/9698/5878/81567/10717/6845/375/4952 44 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-164952 The role of Nef in HIV-1 replication and disease pathogenesis 25/4699 27/10654 1.4622380468990135e-7 5.131481821596252e-7 2.0852175343418575e-7 162/1174/567/2534/163/55690/5062/5879/51606/161/10053/926/3932/1175/8907/940/1173/160/920/8905/164/919/130340/3055/375 25 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress 25/4699 27/10654 1.4622380468990135e-7 5.131481821596252e-7 2.0852175343418575e-7 5393/23404/3576/4801/6347/11340/468/1054/8570/23016/118460/5073/1051/4800/22926/51010/56915/167227/22894/440/4802/1649/51013/467/54512 25 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-500792 GPCR ligand binding 261/4699 468/10654 1.465615534515739e-7 5.131481821596252e-7 2.0852175343418575e-7 729230/2788/2532/10316/2149/1880/7852/7478/50833/5726/338442/64805/1237/2550/50832/3354/2841/4987/51289/259294/2150/2912/6349/3576/6360/4985/2920/2921/1236/259295/9568/554/2840/2831/5367/3549/4988/6370/58191/6755/1524/643/5029/2782/185/339403/2914/8843/2847/2833/6347/9290/9170/6469/187/6750/259296/259289/50835/2587/53829/2787/6387/4544/4543/10663/4889/2535/9283/727/1909/338398/117579/3579/6375/23566/2358/2916/259293/8322/6846/5179/10681/6367/7471/8811/56923/2832/27199/2826/5727/6376/165140/27198/89780/5443/6354/3627/2792/54429/50846/3361/6346/134/9034/8321/1129/7349/51083/2785/2783/2784/2829/1233/6366/2861/728/7474/183/10022/170589/7479/6373/57121/5731/7855/1132/1814/80835/3362/6357/8698/9934/6869/6361/50840/2791/2147/1813/50865/10803/2913/351/11251/3352/8484/6351/6863/6752/135/1903/84539/6753/3577/2918/5368/6754/8862/301/56670/150/2853/6751/186/53637/10563/5540/1901/5733/256933/7252/5729/10850/624/2641/1392/4852/2786/50838/5473/4283/1910/11255/10874/83756/147/6356/56477/259286/3350/129521/1234/151/57007/9294/54331/1128/283869/59345/4986/6608/6374/5539/259287/2852/50836/1230/846/3358/4886/2919/51764/94235/259290/5196/3827/5173/2357/55970/2778/6352/140/6348/152/1906/6364/80834/259292/5031/2793/5030/5697/3355/3351/6288/6372/50834/259285/719/6363/2917/1268/50831/2359/50839/2846/5660/1815/1325/1232/1902/551/154/50837/1269/59340/5724/4887/2790/718/623 261 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9006936 Signaling by TGF-beta family members 71/4699 102/10654 1.5304665532038066e-7 5.345211544025235e-7 2.172068268752195e-7 892/7321/4738/130399/8239/9612/4609/4089/22938/23327/4088/650/5499/1030/9110/7040/904/7314/5054/7027/6497/51592/50848/7323/6667/4092/11171/7050/7046/5494/9958/9040/6233/7514/1025/57530/4091/5500/268/4090/4221/4093/5590/9765/3726/5501/1024/23645/8812/1874/142/905/4087/7048/7311/387/57154/51377/10273/4086/658/64750/659/54778/7316/9611/5933/867/3065/6498/657 71 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 19/4699 19/10654 1.7238990370539905e-7 5.932240803979909e-7 2.410612172557438e-7 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 19/4699 19/10654 1.7238990370539905e-7 5.932240803979909e-7 2.410612172557438e-7 11065/7321/8697/51529/29945/51434/29882/996/51433/119504/7324/64682/246184/8881/10393/51343/25906/991/8556 19 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-176412 Phosphorylation of the APC/C 19/4699 19/10654 1.7238990370539905e-7 5.932240803979909e-7 2.410612172557438e-7 11065/7321/8697/51529/29945/51434/29882/996/983/51433/119504/7324/64682/246184/8881/891/10393/25906/5347 19 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 19/4699 19/10654 1.7238990370539905e-7 5.932240803979909e-7 2.410612172557438e-7 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-77595 Processing of Intronless Pre-mRNAs 19/4699 19/10654 1.7238990370539905e-7 5.932240803979909e-7 2.410612172557438e-7 51585/81608/1477/53981/11051/8106/1478/23283/10914/10898/51692/22916/1479/79869/29894/4686/8189/10978/55339 19 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8851708 Signaling by FGFR2 IIIa TM 19/4699 19/10654 1.7238990370539905e-7 5.932240803979909e-7 2.410612172557438e-7 5431/5435/5433/5439/5438/2247/2246/2963/5434/5436/2263/2962/5432/22916/5440/5430/5441/4686/5437 19 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2426168 Activation of gene expression by SREBF (SREBP) 35/4699 42/10654 1.853495946242803e-7 6.362612001283362e-7 2.5854968546225697e-7 79718/5469/1387/6907/4801/10499/23054/85441/31/96764/4598/5465/2222/6667/3156/6604/80205/10654/6319/6721/9453/4800/32/1595/4047/4802/6720/2194/1717/6256/10498/2224/3422/4520/8648 35 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-180786 Extension of Telomeres 27/4699 30/10654 1.878867549215198e-7 6.402742813344995e-7 2.601804322112001e-7 2237/1763/5982/5422/6117/10714/6118/3978/5557/5985/5984/23649/8607/5424/55651/54107/5425/5111/6119/5427/55135/5983/56655/7015/10856/1736/5981 27 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654696 Downstream signaling of activated FGFR2 27/4699 30/10654 1.878867549215198e-7 6.402742813344995e-7 2.601804322112001e-7 5295/4893/2250/5335/2885/2252/3845/3265/5290/8823/8074/2249/2248/2247/2246/2251/5781/6464/2263/6654/2549/8817/2254/26281/10818/2255/27006 27 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6804758 Regulation of TP53 Activity through Acetylation 27/4699 30/10654 1.878867549215198e-7 6.402742813344995e-7 2.601804322112001e-7 64769/84289/29117/5928/1107/5371/23774/3622/27154/57459/10000/7994/3066/7157/5608/7862/9219/5931/1108/54815/208/53615/5305/207/2033/3065/5300 27 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 22/4699 23/10654 1.9564018336567148e-7 6.634754044574946e-7 2.6960838897583004e-7 7321/8239/9612/4089/23327/4088/7314/6497/51592/7323/7050/5494/6233/142/4087/7311/64750/54778/7316/9611/3065/6498 22 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 22/4699 23/10654 1.9564018336567148e-7 6.634754044574946e-7 2.6960838897583004e-7 3654/7334/7314/257397/5601/8767/23118/8517/10454/6233/64127/5602/3656/7189/7311/6416/6885/10392/7316/7335/5609/5599 22 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654726 Negative regulation of FGFR1 signaling 29/4699 33/10654 2.0974247130242614e-7 7.095865776110995e-7 2.883460226909701e-7 2250/8569/2885/5518/7314/5515/5594/8074/2260/2249/6714/2248/2247/6233/2246/2251/5781/673/7311/5595/5516/10253/2254/7316/26281/10818/867/2255/27006 29 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-163685 Integration of energy metabolism 74/4699 108/10654 2.3146149305874806e-7 7.811825390732747e-7 3.1743959827389037e-7 2788/6804/5563/2770/5578/2769/107/2782/3630/2776/8826/5518/31/2181/6513/5515/2787/5567/784/51422/10681/112/5573/5528/111/2792/5519/51085/2785/2783/2784/2771/9370/7086/6844/2182/196883/115/2791/5568/150/113/5566/775/32/6794/2641/6514/2786/5577/6888/5207/5565/109/6812/5516/54331/5575/59345/51764/94235/114/108/55970/2778/2194/10768/152/2793/5576/47/5906/9630/2790 74 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9020591 Interleukin-12 signaling 38/4699 47/10654 2.5811460861473656e-7 8.690477469906238e-7 3.5314430864366336e-7 759/3593/5908/3313/6175/3717/3181/4001/3594/4282/5062/1072/3592/6627/9049/27250/9987/3185/3458/5478/302/7297/6775/9446/3595/4478/998/6648/3716/2939/6888/3586/829/6950/6845/375/5721/5034 38 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-109704 PI3K Cascade 36/4699 44/10654 3.0592392748265375e-7 1.0275530961379088e-6 4.175541896136952e-7 5295/2250/5291/9965/2264/2885/8660/9846/2252/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/2246/2251/5781/30849/5170/2263/208/2549/8817/2254/152831/26281/10818/2261/2255/27006/5296 36 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6803529 FGFR2 alternative splicing 24/4699 26/10654 3.085416942369749e-7 1.0314108064493163e-6 4.1912180019158e-7 54845/5431/5435/5433/5439/7072/7073/5438/3185/4670/5725/2963/5434/5436/2962/5432/22916/5440/5430/3178/5441/4686/5437/3187 24 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-912694 Regulation of IFNA signaling 24/4699 26/10654 3.085416942369749e-7 1.0314108064493163e-6 4.1912180019158e-7 3443/5777/5770/9021/11274/3445/3444/3451/3448/3439/3452/6773/7297/5781/3446/3455/6772/8651/3440/3454/3716/3456/3441/3449 24 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-195721 Signaling by WNT 191/4699 331/10654 3.10436428279391e-7 1.0352796800576364e-6 4.2069394706195756e-7 2788/8454/27123/9070/5689/857/7478/5579/5682/1459/5526/1452/5578/1212/5929/5582/27327/1460/143471/5705/6657/2775/8452/5530/55366/5709/9978/5695/1457/9559/4609/5711/1387/5683/324/5699/8312/2782/5702/192669/1855/90780/163/5518/4343/25776/3845/6659/80351/5696/5691/4920/7314/5879/5515/2787/5718/8945/2535/161/6662/51701/5700/122706/5707/1856/1454/8322/23198/10681/7471/7534/5528/89780/2792/59349/9861/81847/5519/2932/8321/9580/5698/5692/5713/2785/2783/23002/2784/5710/8313/5719/6233/7474/1857/7514/4040/7479/1213/1211/7855/331/8607/1175/26523/801/2791/4221/123169/1173/144165/6597/864/4772/10023/4041/409/79577/6736/5706/160/23401/8658/5714/6934/10524/5688/5687/4919/5708/5529/2786/208/57680/5704/7311/387/5694/5516/57154/27161/815/5684/8295/5720/54331/7015/6885/1487/1499/5525/59345/139285/207/8085/5690/5532/57690/5717/9491/6500/51764/94235/10197/192670/64750/7316/10213/55970/5216/5715/5701/2793/1455/5685/5686/2033/54894/5534/3065/23112/23513/5527/1488/5716/23072/5693/5721/6259/2790/5592 191 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-199992 trans-Golgi Network Vesicle Budding 53/4699 72/10654 3.380843756216985e-7 1.124811524580248e-6 4.5707590817400994e-7 8773/8906/162/1176/27243/5286/1212/1174/1785/8546/7037/3482/408/6456/3312/25977/10618/10053/55330/8301/9146/4074/2495/388552/6844/1213/2580/1211/23431/8907/351/84062/9685/9179/9026/8775/9829/8905/51429/8673/2512/164/130340/6272/2799/7163/9698/5878/81567/10717/6845/375/4952 53 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1368082 RORA activates gene expression 18/4699 18/10654 3.916981448003888e-7 1.293986341881755e-6 5.25821410481265e-7 79718/5469/1387/6907/10499/23054/85441/96764/5465/6604/80205/1374/6095/6720/2033/6256/10498/8648 18 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5675482 Regulation of necroptotic cell death 18/4699 18/10654 3.916981448003888e-7 1.293986341881755e-6 5.25821410481265e-7 356/7314/8737/841/8797/6233/8772/331/8717/8743/330/8837/7311/8795/7186/355/7316/329 18 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8964315 G beta:gamma signalling through BTK 18/4699 18/10654 3.916981448003888e-7 1.293986341881755e-6 5.25821410481265e-7 2788/2782/2787/10681/2792/2785/2783/2784/2791/695/2786/54331/59345/51764/94235/55970/2793/2790 18 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 32/4699 38/10654 3.938620745239774e-7 1.2980806399804327e-6 5.274851603459247e-7 1912/1459/6045/80012/1460/28996/1457/1911/6603/10138/57332/86/865/84733/6604/8289/6602/23429/55193/6015/6595/6597/8535/6599/648/6601/23466/6598/2033/84333/6605/861 32 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-392518 Signal amplification 28/4699 32/10654 4.2073814435739945e-7 1.3769611997151256e-6 5.59538889073023e-7 2788/64805/2770/2769/1432/2782/2776/2773/2787/10681/2792/6714/2785/2783/2784/2771/2791/2786/5321/54331/59345/51764/94235/55970/346562/2793/9630/2790 28 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5656169 Termination of translesion DNA synthesis 28/4699 32/10654 4.2073814435739945e-7 1.3769611997151256e-6 5.59538889073023e-7 5982/6117/10714/7314/6118/9636/11201/51455/5985/5984/6233/5424/124739/54107/7706/5425/5111/6119/5427/9246/51426/7311/7318/5983/56655/7316/9100/5981 28 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69190 DNA strand elongation 28/4699 32/10654 4.2073814435739945e-7 1.3769611997151256e-6 5.59538889073023e-7 2237/1763/5982/5422/4174/84515/6117/10714/6118/3978/5557/5985/4175/5984/23649/5424/4172/8318/4173/5425/5111/6119/51659/5983/4176/9837/4171/5981 28 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 21/4699 22/10654 4.2595351104023783e-7 1.3875608573097306e-6 5.638461423465843e-7 3725/7531/356/7001/4001/826/823/2801/993/351/6648/1020/4000/994/2309/10018/831/824/995/8851/5052 21 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8863678 Neurodegenerative Diseases 21/4699 22/10654 4.2595351104023783e-7 1.3875608573097306e-6 5.638461423465843e-7 3725/7531/356/7001/4001/826/823/2801/993/351/6648/1020/4000/994/2309/10018/831/824/995/8851/5052 21 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-76002 Platelet activation, signaling and aggregation 155/4699 262/10654 5.1315408700909e-7 1.6677507827795423e-6 6.777034969759423e-7 5295/2788/2149/5777/8526/5579/5770/5291/7042/64805/2770/5175/3959/5578/5582/5908/3082/388/5583/2769/5267/1432/3920/2244/3309/2534/3690/408/2782/87/2776/5894/10487/2885/7040/350/7043/2773/967/5879/5054/2787/5099/1072/5290/7018/5336/7094/5594/10681/7414/10490/7534/2792/6714/7273/22927/1191/27154/5588/2335/2785/2783/2784/1445/8525/5478/2771/5580/2266/7409/3932/7076/2243/8527/801/5781/2791/2147/5170/5590/351/6464/135228/5747/51097/3937/2316/3674/409/7277/221955/334/10447/150/10257/335/308/6850/8503/6403/197/4067/81/9948/998/3481/2786/6654/5473/8407/7450/387/29789/10916/5595/151/5321/54331/5005/59345/207/7422/5004/51764/94235/5196/3827/54518/1950/55970/5216/346562/152/27040/2793/5265/7078/55664/5345/2/1398/5906/3479/5296/5581/51368/213/5660/9630/7057/2207/6814/2790/3700 155 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-4551638 SUMOylation of chromatin organization proteins 52/4699 71/10654 5.706127207962208e-7 1.8502084526510253e-6 7.518465896962482e-7 1912/23165/6045/80012/348995/6613/57122/23511/9759/1911/23279/23225/23512/57332/1107/9972/6612/8021/55746/83746/10762/79902/9883/84733/3066/9063/6396/129401/7703/6015/8554/4928/5903/55706/7175/8535/4927/8086/7329/648/23468/81929/9631/79023/23636/53371/9688/7341/3065/23314/6304/8480 52 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2559583 Cellular Senescence 120/4699 195/10654 5.903018307209133e-7 1.9096400238068255e-6 7.759970707027287e-7 1912/3725/9134/2077/11065/4790/7321/6045/8697/27327/80012/7295/5925/472/79813/3576/2114/1869/1911/26277/4194/1031/5928/1432/4683/23512/57332/192669/8900/51529/4001/29945/8091/51434/1030/6196/4343/6197/29882/4217/54386/3569/7314/996/7014/5601/5606/7027/2146/5594/898/890/5970/9261/6667/51433/5598/84733/119504/6195/7157/7324/64682/6233/2353/8726/5600/26523/5608/6015/1019/9448/246184/1029/8535/5931/7013/1051/8881/6774/7867/3552/10524/5602/10393/1870/51343/7311/25906/57634/648/23466/3456/2113/6416/23523/5595/1017/3159/7290/10111/57690/1027/192670/3490/8550/29855/7316/1026/1871/65057/1021/25842/23135/23112/5609/5599/10919/4193/23043 120 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-418592 ADP signalling through P2Y purinoceptor 1 23/4699 25/10654 6.49092039062857e-7 2.0901954652391084e-6 8.493671781073601e-7 2788/2769/1432/2782/2776/2787/10681/2792/6714/2785/2783/2784/2791/2786/5321/54331/59345/51764/94235/55970/2793/9630/2790 23 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 23/4699 25/10654 6.49092039062857e-7 2.0901954652391084e-6 8.493671781073601e-7 5982/6117/10714/7314/6118/3978/5985/5984/6233/5424/7515/54107/5425/5111/6119/5427/51426/7311/3980/5983/56655/7316/5981 23 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 25/4699 28/10654 7.88881676402815e-7 2.5345306033628196e-6 1.0299262160913545e-6 2788/2770/2782/2787/784/10681/112/111/2792/2785/2783/2784/2771/2791/150/775/2786/54331/59345/51764/94235/55970/152/2793/2790 25 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 44/4699 58/10654 8.273456812492295e-7 2.62803922279167e-6 1.0679241706051023e-6 8454/79718/892/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/8850/3066/6233/5663/142678/10046/1024/10014/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 44 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2644603 Signaling by NOTCH1 in Cancer 44/4699 58/10654 8.273456812492295e-7 2.62803922279167e-6 1.0679241706051023e-6 8454/79718/892/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/8850/3066/6233/5663/142678/10046/1024/10014/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 44 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 44/4699 58/10654 8.273456812492295e-7 2.62803922279167e-6 1.0679241706051023e-6 8454/79718/892/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/8850/3066/6233/5663/142678/10046/1024/10014/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 44 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 44/4699 58/10654 8.273456812492295e-7 2.62803922279167e-6 1.0679241706051023e-6 8454/79718/892/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/8850/3066/6233/5663/142678/10046/1024/10014/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 44 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 44/4699 58/10654 8.273456812492295e-7 2.62803922279167e-6 1.0679241706051023e-6 8454/79718/892/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/8850/3066/6233/5663/142678/10046/1024/10014/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 44 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-164378 PKA activation in glucagon signalling 17/4699 17/10654 8.89896020128523e-7 2.7888705630813534e-6 1.1332792361599144e-6 107/5567/112/5573/111/196883/115/5568/113/5566/5577/109/5575/114/108/2778/5576 17 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-196299 Beta-catenin phosphorylation cascade 17/4699 17/10654 8.89896020128523e-7 2.7888705630813534e-6 1.1332792361599144e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/10023/23401/5529/5516/1499/5525/139285/5527 17 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-450385 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA 17/4699 17/10654 8.89896020128523e-7 2.7888705630813534e-6 1.1332792361599144e-6 5393/23404/11340/9261/23016/118460/677/51010/56915/167227/7529/22894/207/55802/51013/54464/54512 17 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-450513 Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA 17/4699 17/10654 8.89896020128523e-7 2.7888705630813534e-6 1.1332792361599144e-6 5393/23404/11340/9261/23016/118460/3842/7538/51010/56915/167227/7529/22894/55802/51013/54464/54512 17 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-450604 KSRP (KHSRP) binds and destabilizes mRNA 17/4699 17/10654 8.89896020128523e-7 2.7888705630813534e-6 1.1332792361599144e-6 5393/23404/1432/11340/7534/5600/8570/23016/118460/5073/51010/56915/167227/22894/207/51013/54512 17 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8934593 Regulation of RUNX1 Expression and Activity 17/4699 17/10654 8.89896020128523e-7 2.7888705630813534e-6 1.1332792361599144e-6 27327/192669/5371/4343/865/6714/595/896/26523/5781/27161/894/57690/192670/1021/861/23112 17 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 58/4699 82/10654 8.997252681485459e-7 2.8071428366234634e-6 1.140704316576636e-6 10844/7531/11190/203068/54801/79441/5116/5048/8655/7846/11064/5518/55835/23332/93323/1454/983/80097/10540/54930/54820/1453/27229/9793/22981/7532/10382/121441/7277/23354/9738/1639/4957/5566/7283/22919/10426/1069/5577/10383/5347/80184/22897/1778/115106/22995/55559/10142/95681/1781/10121/84131/3320/10733/4751/9662/55142/8481 58 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-380287 Centrosome maturation 58/4699 82/10654 8.997252681485459e-7 2.8071428366234634e-6 1.140704316576636e-6 10844/7531/11190/203068/54801/79441/5116/5048/8655/7846/11064/5518/55835/23332/93323/1454/983/80097/10540/54930/54820/1453/27229/9793/22981/7532/10382/121441/7277/23354/9738/1639/4957/5566/7283/22919/10426/1069/5577/10383/5347/80184/22897/1778/115106/22995/55559/10142/95681/1781/10121/84131/3320/10733/4751/9662/55142/8481 58 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 20/4699 21/10654 9.255019508443467e-7 2.8811635010764143e-6 1.1707831890713873e-6 25904/55571/55835/57472/85456/29883/1263/7832/10769/7157/5325/4869/4850/246175/4848/23019/4849/9337/28984/995 20 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-373076 Class A/1 (Rhodopsin-like receptors) 191/4699 335/10654 9.722128396901238e-7 3.0198823604533935e-6 1.227152676087674e-6 729230/2532/10316/2149/1880/7852/338442/64805/1237/3354/2841/4987/51289/2150/6349/3576/6360/4985/2920/2921/1236/554/2840/2831/5367/4988/6370/58191/6755/1524/643/5029/185/339403/8843/2847/2833/6347/9290/9170/187/6750/2587/53829/6387/4544/4543/10663/4889/9283/727/1909/117579/3579/6375/23566/2358/6846/5179/6367/8811/56923/2832/27199/2826/6376/165140/27198/5443/6354/3627/3361/6346/134/9034/1129/51083/2829/1233/6366/2861/728/183/10022/170589/6373/57121/5731/1132/1814/3362/6357/8698/9934/6869/6361/2147/1813/50865/10803/351/11251/3352/8484/6351/6863/6752/135/1903/84539/6753/3577/5368/6754/8862/301/56670/150/2853/6751/186/53637/10563/5540/1901/5733/256933/7252/5729/10850/624/4852/5473/4283/1910/11255/10874/147/6356/56477/3350/129521/1234/151/57007/9294/1128/283869/4986/6374/5539/2852/1230/3358/4886/2919/5196/3827/5173/2357/6352/140/6348/152/1906/6364/5031/5030/5697/3355/3351/6288/6372/719/6363/1268/2359/2846/5660/1815/1325/1232/1902/551/154/1269/59340/5724/4887/718/623 191 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-982772 Growth hormone receptor signaling 22/4699 24/10654 1.3611153116610888e-6 4.218556065280725e-6 1.7142430554672014e-6 5777/5770/9021/6776/3717/5618/6868/8660/1154/3667/2690/5594/5617/8835/6777/6774/6772/8651/4067/2689/5595/2688 22 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 24/4699 27/10654 1.607084810613568e-6 4.959004558464725e-6 2.015130057495787e-6 356/836/929/26060/1612/8737/841/8797/1613/8772/8717/8743/8837/8795/23643/7186/842/355/7099/9500/23604/1630/353376/148022 24 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654716 Downstream signaling of activated FGFR4 24/4699 27/10654 1.607084810613568e-6 4.959004558464725e-6 2.015130057495787e-6 5295/4893/5335/9965/2264/2885/3845/3265/5290/8823/8074/2249/2247/2246/2251/5781/6464/6654/2549/8817/2254/152831/26281/10818 24 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2424491 DAP12 signaling 26/4699 30/10654 1.6715544743827969e-6 5.146628250073349e-6 2.0913724033136567e-6 5295/4893/5335/7305/5291/3824/567/2534/3822/2885/3133/3845/3265/5879/5290/5336/3932/6464/3937/6850/22914/695/6654/9402/27040/5296 26 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-177929 Signaling by EGFR 38/4699 49/10654 1.8195076908390262e-6 5.589909842315082e-6 2.271503324737423e-6 5295/374/4893/5335/55824/6456/6868/30011/2885/8874/3845/3265/5829/7314/5290/8027/2060/6714/9146/6455/1445/6233/29924/5781/6464/5782/998/6654/7311/1956/2549/10253/58513/7316/1950/867/10254/6457 38 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2682334 EPH-Ephrin signaling 63/4699 92/10654 1.8708629923555992e-6 5.735134587919784e-6 2.330516529204171e-6 71/2042/1947/1212/23385/10094/79784/2047/2534/9475/4628/8976/6093/163/8997/1759/8440/8874/3265/5062/5879/1072/161/10093/5921/6453/4313/6714/7525/1213/1211/1175/10109/5663/1173/2904/5747/7074/10627/4318/160/8218/10092/4067/5063/6386/998/2048/10097/387/60/5058/4629/28964/4627/6383/10398/10552/4637/10096/103910/10095/1969 63 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 19/4699 20/10654 2.0064336888250306e-6 6.06451880981885e-6 2.4643643686623306e-6 7321/7334/3551/7314/11035/8737/8517/7323/6233/330/7098/7189/7311/1147/7316/7335/7322/329/148022 19 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5213460 RIPK1-mediated regulated necrosis 19/4699 20/10654 2.0064336888250306e-6 6.06451880981885e-6 2.4643643686623306e-6 356/7314/11035/8737/841/8797/6233/8772/331/8717/8743/330/8837/7311/8795/7186/355/7316/329 19 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5218859 Regulated Necrosis 19/4699 20/10654 2.0064336888250306e-6 6.06451880981885e-6 2.4643643686623306e-6 356/7314/11035/8737/841/8797/6233/8772/331/8717/8743/330/8837/7311/8795/7186/355/7316/329 19 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5625900 RHO GTPases activate CIT 19/4699 20/10654 2.0064336888250306e-6 6.06451880981885e-6 2.4643643686623306e-6 388/79784/4628/5879/4659/389/11113/9055/5500/10627/387/4660/4629/4627/1027/10398/4637/9928/103910 19 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 19/4699 20/10654 2.0064336888250306e-6 6.06451880981885e-6 2.4643643686623306e-6 472/1387/51499/7159/637/27166/23368/7157/63970/55240/5366/84883/147923/94241/8626/7161/665/27113/581 19 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8876384 Listeria monocytogenes entry into host cells 19/4699 20/10654 2.0064336888250306e-6 6.06451880981885e-6 2.4643643686623306e-6 6456/30011/2885/7314/8027/2060/1500/6714/999/9146/6455/6233/4233/7311/1499/7316/867/10254/6457 19 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1295596 Spry regulation of FGF signaling 16/4699 16/10654 2.0215062699396164e-6 6.06451880981885e-6 2.4643643686623306e-6 8569/2885/5518/7314/5515/5594/6714/6233/5781/673/7311/5595/5516/10253/7316/867 16 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-193639 p75NTR signals via NF-kB 16/4699 16/10654 2.0215062699396164e-6 6.06451880981885e-6 2.4643643686623306e-6 4790/8878/4792/3654/3551/7314/8767/5970/6233/7189/7311/4804/5584/4615/7316/4803 16 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 16/4699 16/10654 2.0215062699396164e-6 6.06451880981885e-6 2.4643643686623306e-6 8454/4790/3551/7314/8945/1326/8517/6233/79155/7311/6416/1147/5604/6500/7316/23291 16 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9614657 FOXO-mediated transcription of cell death genes 16/4699 16/10654 2.0215062699396164e-6 6.06451880981885e-6 2.4643643686623306e-6 2308/65018/356/1387/4801/604/4303/4800/10370/6794/27113/2309/10018/4802/1649/2033 16 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-381119 Unfolded Protein Response (UPR) 64/4699 94/10654 2.1187206554979997e-6 6.342609382343692e-6 2.577368634900496e-6 5393/1965/2673/23404/5526/811/3576/55738/10130/3309/4801/6347/11340/9820/10488/9695/84699/7094/468/22872/51726/3068/1054/8894/7466/9451/2931/8570/23016/148327/118460/1968/1200/6464/37/5073/7184/7494/118/1051/84447/5611/4800/1639/10954/22926/90993/51010/64764/56915/167227/22894/4000/440/4802/116138/1649/2081/30827/51013/467/10106/54512/7709 64 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-111465 Apoptotic cleavage of cellular proteins 31/4699 38/10654 2.3709022850949767e-6 7.082440017602867e-6 2.87800456555762e-6 836/324/9414/4001/6709/6093/840/2934/22985/63967/841/7082/5339/28988/10134/999/5588/5580/839/1828/5747/118/8428/1832/4000/51765/1499/329/4137/7431/6304 31 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-432720 Lysosome Vesicle Biogenesis 29/4699 35/10654 2.766564298647912e-6 8.24682860998231e-6 3.3511629229347823e-6 8906/162/27243/1212/1174/1785/408/6456/3312/10053/9146/4074/6844/1213/1211/23431/8907/351/9179/9829/8905/8673/164/130340/2799/81567/10717/6845/375 29 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654695 PI-3K cascade:FGFR2 21/4699 23/10654 2.8442434516231753e-6 8.442532359574922e-6 3.430688663135108e-6 5295/2250/2885/2252/5290/8823/8074/2249/2248/2247/2246/2251/5781/2263/2549/8817/2254/26281/10818/2255/27006 21 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654699 SHC-mediated cascade:FGFR2 21/4699 23/10654 2.8442434516231753e-6 8.442532359574922e-6 3.430688663135108e-6 4893/2250/2885/2252/3845/3265/8823/8074/2249/2248/2247/2246/2251/6464/2263/6654/8817/2254/26281/2255/27006 21 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-75893 TNF signaling 34/4699 43/10654 2.9305524955555144e-6 8.680370683037852e-6 3.527336115014632e-6 7124/7375/9530/10616/6868/1540/3551/7314/257397/90268/81858/8737/55072/23118/841/8517/7128/10454/6233/8772/331/8717/330/27005/8567/7311/1147/7186/56957/6885/7316/7132/329/9099 34 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2173789 TGF-beta receptor signaling activates SMADs 27/4699 32/10654 3.1071032598247474e-6 9.145436010050199e-6 3.716319026426157e-6 4738/4089/23327/4088/5499/9110/7040/7314/4092/11171/7046/9958/9040/6233/7514/5500/5501/23645/4087/7048/7311/57154/51377/10273/64750/7316/867 27 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 27/4699 32/10654 3.1071032598247474e-6 9.145436010050199e-6 3.716319026426157e-6 892/4609/4089/22938/4088/1030/904/7314/5054/7027/6667/4092/7050/6233/1025/4221/3726/1024/8812/1874/905/4087/7311/54778/7316/5933/3065 27 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 27/4699 32/10654 3.1071032598247474e-6 9.145436010050199e-6 3.716319026426157e-6 2788/2149/2769/408/2782/2776/2787/5594/10681/2792/6714/2785/2783/2784/2791/2147/409/2786/5595/54331/59345/51764/94235/55970/2793/9630/2790 27 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-180024 DARPP-32 events 23/4699 26/10654 3.259978016061269e-6 9.555342660855995e-6 3.882887780914642e-6 5530/5499/5518/5515/84152/5567/5142/5573/5528/5519/801/5568/5566/5577/1020/5141/5516/5533/5575/5532/5576/5534/5144 23 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2173788 Downregulation of TGF-beta receptor signaling 23/4699 26/10654 3.259978016061269e-6 9.555342660855995e-6 3.882887780914642e-6 23327/4088/5499/9110/7040/7314/4092/11171/7046/9958/6233/7514/5500/5501/23645/4087/7048/7311/57154/51377/10273/64750/7316 23 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 25/4699 29/10654 3.3087101694431745e-6 9.671607622420169e-6 3.9301329519806054e-6 2308/84676/4089/4088/3630/56729/2538/847/5443/3066/2645/5105/4303/23410/4287/2908/4852/6648/4087/25942/2309/6720/114907/3065/10891 25 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-442755 Activation of NMDA receptors and postsynaptic events 63/4699 93/10654 3.313421129903206e-6 9.671607622420169e-6 3.9301329519806054e-6 5563/4893/51807/817/347688/53632/10381/107/7846/81027/6196/1740/8874/6197/3845/3265/814/5879/5923/818/5567/5594/51422/5573/6714/22843/10376/6195/5613/801/2891/57576/5170/84617/3838/8573/2904/10382/5568/7277/55327/5566/5571/27330/3084/816/5577/5562/10383/84790/5564/5565/7280/5595/815/28964/5575/114/5576/4137/2066/1385/8536 63 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-392851 Prostacyclin signalling through prostacyclin receptor 18/4699 19/10654 4.339246484510209e-6 1.2613461830750174e-5 5.125578281801315e-6 2788/2782/2787/10681/2792/2785/2783/2784/2791/2786/54331/59345/51764/94235/55970/2778/2793/2790 18 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6804760 Regulation of TP53 Activity through Methylation 18/4699 19/10654 4.339246484510209e-6 1.2613461830750174e-5 5.125578281801315e-6 133383/11200/472/79813/4194/56950/7314/7157/6233/10419/26013/7311/7316/2033/91875/133746/10919/4193 18 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-111447 Activation of BAD and translocation to mitochondria 15/4699 15/10654 4.5915467988658326e-6 1.2997039729047639e-5 5.281448143007813e-6 7531/10971/7533/2810/637/7534/10000/572/7532/208/7529/5533/596/207/5534 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-354194 GRB2:SOS provides linkage to MAPK signaling for Integrins 15/4699 15/10654 4.5915467988658326e-6 1.2997039729047639e-5 5.281448143007813e-6 5908/2244/3690/2885/7094/6714/2335/2266/2243/5747/3674/6654/7450/54518/5906 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-430039 mRNA decay by 5' to 3' exoribonuclease 15/4699 15/10654 4.5915467988658326e-6 1.2997039729047639e-5 5.281448143007813e-6 80153/219988/51690/11157/23644/27258/57819/23658/167227/1656/27257/25804/55802/196513/54464 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 15/4699 15/10654 4.5915467988658326e-6 1.2997039729047639e-5 5.281448143007813e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5099900 WNT5A-dependent internalization of FZD4 15/4699 15/10654 4.5915467988658326e-6 1.2997039729047639e-5 5.281448143007813e-6 5579/5578/1212/5582/163/161/1856/8322/7474/1213/1211/1175/1173/409/160 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 15/4699 15/10654 4.5915467988658326e-6 1.2997039729047639e-5 5.281448143007813e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 15/4699 15/10654 4.5915467988658326e-6 1.2997039729047639e-5 5.281448143007813e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 15/4699 15/10654 4.5915467988658326e-6 1.2997039729047639e-5 5.281448143007813e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 15/4699 15/10654 4.5915467988658326e-6 1.2997039729047639e-5 5.281448143007813e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 15/4699 15/10654 4.5915467988658326e-6 1.2997039729047639e-5 5.281448143007813e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5637810 Constitutive Signaling by EGFRvIII 15/4699 15/10654 4.5915467988658326e-6 1.2997039729047639e-5 5.281448143007813e-6 5295/4893/5335/2885/3845/3265/5290/6464/6654/1956/2549/11140/1950/867/3320 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5637812 Signaling by EGFRvIII in Cancer 15/4699 15/10654 4.5915467988658326e-6 1.2997039729047639e-5 5.281448143007813e-6 5295/4893/5335/2885/3845/3265/5290/6464/6654/1956/2549/11140/1950/867/3320 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 15/4699 15/10654 4.5915467988658326e-6 1.2997039729047639e-5 5.281448143007813e-6 6456/30011/2885/7314/8027/2060/9146/6455/6233/4233/7311/7316/867/10254/6457 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 28/4699 34/10654 5.242937870159888e-6 1.4811035753932561e-5 6.018579531137688e-6 7321/9140/9474/3093/83737/7187/1540/7314/29110/9636/7323/23586/7128/3661/51191/6233/55593/54476/7706/9246/7311/7318/5094/57506/7316/7322/54941/5300 28 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-3928662 EPHB-mediated forward signaling 33/4699 42/10654 5.306538551471692e-6 1.4960602663185252e-5 6.079357207562159e-6 71/1947/10094/2047/2534/9475/8976/6093/8997/3265/5879/1072/10093/5921/6453/6714/7525/10109/2904/5747/7074/10092/4067/998/2048/10097/387/60/5058/6383/10552/10096/10095 33 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-113510 E2F mediated regulation of DNA replication 20/4699 22/10654 5.920986348885448e-6 1.6526967860507296e-5 6.715861883636944e-6 5925/5422/1869/84515/4998/28227/5518/5001/5515/23594/7027/5557/983/5519/23649/4999/5000/891/23595/5516 20 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-389357 CD28 dependent PI3K/Akt signaling 20/4699 22/10654 5.920986348885448e-6 1.6526967860507296e-5 6.715861883636944e-6 5295/941/2534/2475/1326/5290/57761/9020/10000/3932/940/253260/5170/64223/8503/208/79109/207/942/5296 20 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5655332 Signaling by FGFR3 in disease 20/4699 22/10654 5.920986348885448e-6 1.6526967860507296e-5 6.715861883636944e-6 5295/4893/2250/5335/2885/3845/3265/5290/8823/8074/2249/2247/2246/6654/2549/8817/2254/26281/10818/2261 20 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 20/4699 22/10654 5.920986348885448e-6 1.6526967860507296e-5 6.715861883636944e-6 5295/4893/2250/5335/2885/3845/3265/5290/8823/8074/2249/2247/2246/6654/2549/8817/2254/26281/10818/2261 20 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-912631 Regulation of signaling by CBL 20/4699 22/10654 5.920986348885448e-6 1.6526967860507296e-5 6.715861883636944e-6 5295/5291/2534/2885/1399/7314/5290/6233/7525/7409/6850/8503/4067/7311/5293/7316/3055/867/1398/5296 20 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1839124 FGFR1 mutant receptor activation 26/4699 31/10654 5.993127734197652e-6 1.6695141545264887e-5 6.7842005679513944e-6 5295/11052/2250/9530/613/6776/11064/2885/9846/7750/8805/26127/5290/8074/2260/2249/399687/2247/2246/2251/6777/6774/6772/11160/2254/26281 26 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69205 G1/S-Specific Transcription 24/4699 28/10654 6.516303615878073e-6 1.81166144092927e-5 7.361827117886223e-6 5422/1869/4998/5928/990/8900/6241/7027/898/5934/1876/983/7298/1719/26271/8318/286826/5111/1874/81620/55957/5933/3065/7083 24 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-392451 G beta:gamma signalling through PI3Kgamma 22/4699 25/10654 6.582619310714808e-6 1.8121563749497237e-5 7.363838320758361e-6 2788/2782/2787/10681/2792/10000/2785/2783/2784/2791/5170/2786/208/387/54331/59345/207/51764/94235/55970/2793/2790 22 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654700 FRS-mediated FGFR2 signaling 22/4699 25/10654 6.582619310714808e-6 1.8121563749497237e-5 7.363838320758361e-6 4893/2250/2885/2252/3845/3265/8823/8074/2249/2248/2247/2246/2251/5781/2263/6654/8817/2254/26281/10818/2255/27006 22 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654708 Downstream signaling of activated FGFR3 22/4699 25/10654 6.582619310714808e-6 1.8121563749497237e-5 7.363838320758361e-6 5295/4893/2250/5335/2885/3845/3265/5290/8823/8074/2249/2247/2246/5781/6464/6654/2549/8817/2254/26281/10818/2261 22 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9006335 Signaling by Erythropoietin 22/4699 25/10654 6.582619310714808e-6 1.8121563749497237e-5 7.363838320758361e-6 5295/4893/5335/5291/6776/3717/2885/2056/8660/3845/3265/1399/5290/5336/2057/7409/6777/6464/4067/6654/5293/2549 22 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-937041 IKK complex recruitment mediated by RIP1 22/4699 25/10654 6.582619310714808e-6 1.8121563749497237e-5 7.363838320758361e-6 7321/929/7334/3551/7314/11035/8737/8517/7323/6233/330/7189/7311/23643/1147/7099/7316/7335/7322/329/353376/148022 22 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 31/4699 39/10654 6.663273356434971e-6 1.8307702137836983e-5 7.4394771020450205e-6 5982/25898/6117/10714/7314/6118/9636/11201/51455/5985/5984/6233/5424/124739/54107/7706/5425/5111/6119/5427/9246/51426/7311/7318/5983/56655/7316/9100/10459/7415/5981 31 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-72766 Translation 165/4699 291/10654 8.182391107077426e-6 2.2433954349172673e-5 9.116211768819606e-6 6158/6138/5464/6227/6206/1965/6234/27335/6191/6128/6132/1917/84545/6129/1915/9255/6176/8668/51318/6224/6146/6154/8662/26986/6202/65003/6169/6175/6218/6728/64960/6192/6156/6143/1973/28973/51116/6139/51067/64975/3921/8665/6208/6170/6203/10952/6147/8666/6222/64432/8667/6727/6184/2935/6134/6731/6155/6729/6231/6142/8663/23521/23107/8894/1981/6185/6207/64978/1977/6726/6233/28957/219402/51386/6188/1978/64965/7284/200916/6122/1968/6230/8669/6194/2107/1938/1650/1983/6136/6125/1937/10056/6232/6160/6748/29927/1933/6193/6210/6229/6205/54148/140801/23438/6181/740/8893/1975/23471/7311/6223/25873/8664/6730/9045/6187/6168/6157/6137/1974/55037/6144/6182/9349/4736/8891/29088/51121/56945/6217/1936/6152/79590/51065/6141/10480/28998/1967/63931/8661/64963/9669/6209/11224/6165/6130/8890/6204/64969/51081/6228/7965/6124/90480/2193/3646/6189/6135/6201/6161/51649/54998/8892/6133/51021 165 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-167287 HIV elongation arrest and recovery 29/4699 36/10654 8.213000381392274e-6 2.2433954349172673e-5 9.116211768819606e-6 5431/5435/5433/5439/11198/904/51497/5438/1025/7936/6829/25920/2963/5434/5436/2962/8812/905/5432/6917/5440/5430/6749/5441/7469/9150/5437/6827/8178 29 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-167290 Pausing and recovery of HIV elongation 29/4699 36/10654 8.213000381392274e-6 2.2433954349172673e-5 9.116211768819606e-6 5431/5435/5433/5439/11198/904/51497/5438/1025/7936/6829/25920/2963/5434/5436/2962/8812/905/5432/6917/5440/5430/6749/5441/7469/9150/5437/6827/8178 29 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 17/4699 18/10654 9.359259900706797e-6 2.5465893218202217e-5 1.0348263700903886e-5 8792/10673/8740/7187/51330/958/9020/8742/959/4055/8600/330/115650/4050/7186/329/4049 17 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 17/4699 18/10654 9.359259900706797e-6 2.5465893218202217e-5 1.0348263700903886e-5 2810/6790/1647/7027/5934/983/7157/891/5111/1874/25946/5933/2033/995/10498/581/3276 17 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-202433 Generation of second messenger molecules 27/4699 33/10654 9.878655318442539e-6 2.6775351480875143e-5 1.0880372246689406e-5 5335/3115/3113/3117/3127/5062/916/3702/3932/3120/3937/3123/3122/920/5063/7535/5058/55740/9402/4690/3119/919/27040/915/917/51466/7408 27 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5357905 Regulation of TNFR1 signaling 27/4699 33/10654 9.878655318442539e-6 2.6775351480875143e-5 1.0880372246689406e-5 7124/7375/10616/1540/3551/7314/90268/81858/8737/55072/841/8517/7128/6233/331/8717/330/27005/8567/7311/1147/7186/56957/7316/7132/329/9099 27 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-198323 AKT phosphorylates targets in the cytosol 14/4699 14/10654 1.0427760499451979e-5 2.7728363146270036e-5 1.1267635946377538e-5 84335/7249/2932/10000/2931/23608/572/208/1147/842/207/1027/1026/4193 14 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 14/4699 14/10654 1.0427760499451979e-5 2.7728363146270036e-5 1.1267635946377538e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-4839744 truncated APC mutants destabilize the destruction complex 14/4699 14/10654 1.0427760499451979e-5 2.7728363146270036e-5 1.1267635946377538e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-4839748 AMER1 mutants destabilize the destruction complex 14/4699 14/10654 1.0427760499451979e-5 2.7728363146270036e-5 1.1267635946377538e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5467337 APC truncation mutants have impaired AXIN binding 14/4699 14/10654 1.0427760499451979e-5 2.7728363146270036e-5 1.1267635946377538e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 14/4699 14/10654 1.0427760499451979e-5 2.7728363146270036e-5 1.1267635946377538e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 14/4699 14/10654 1.0427760499451979e-5 2.7728363146270036e-5 1.1267635946377538e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 14/4699 14/10654 1.0427760499451979e-5 2.7728363146270036e-5 1.1267635946377538e-5 9134/57060/1869/8900/144455/898/890/7157/79733/1820/1017/25946/1027/1026 14 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 14/4699 14/10654 1.0427760499451979e-5 2.7728363146270036e-5 1.1267635946377538e-5 7159/51230/23368/5458/10000/7157/5457/54971/8626/208/7161/25946/207/10848 14 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-877312 Regulation of IFNG signaling 14/4699 14/10654 1.0427760499451979e-5 2.7728363146270036e-5 1.1267635946377538e-5 5777/5770/9021/3459/3717/3458/5781/8554/6772/8651/5771/3716/3460/7341 14 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-111996 Ca-dependent events 30/4699 38/10654 1.2130553450943216e-5 3.213452272664957e-5 1.3058113148780982e-5 817/5578/5582/107/814/818/5567/5594/112/5573/111/5613/5580/196883/115/801/3838/5568/113/5566/816/5577/109/815/5321/5575/114/108/5576/1385 30 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5689896 Ovarian tumor domain proteases 30/4699 38/10654 1.2130553450943216e-5 3.213452272664957e-5 1.3058113148780982e-5 7321/324/7187/7314/8737/8767/55611/8517/983/2099/23586/7128/7157/6233/55593/10318/7706/79155/79589/64127/7189/7311/387/56957/10392/57506/7316/7415/5728/78990 30 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-111931 PKA-mediated phosphorylation of CREB 19/4699 21/10654 1.227528519964162e-5 3.239567748176097e-5 1.3164235413940955e-5 107/5567/112/5573/111/5613/196883/115/801/5568/113/5566/5577/109/5575/114/108/5576/1385 19 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6807004 Negative regulation of MET activity 19/4699 21/10654 1.227528519964162e-5 3.239567748176097e-5 1.3164235413940955e-5 5770/3082/6456/30011/2885/7314/8027/2060/9146/6455/6233/4233/5795/5771/7311/7316/867/10254/6457 19 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1538133 G0 and Early G1 23/4699 27/10654 1.2764113947385605e-5 3.3622544056527935e-5 1.3662782185213783e-5 9134/1869/4609/5928/990/8900/7027/7153/898/5934/993/890/983/1859/286826/5111/1874/55957/1017/4605/4149/5933/3065 23 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 21/4699 24/10654 1.3226140431357803e-5 3.464459172691484e-5 1.4078099202270091e-5 2237/1763/5982/5422/6117/10714/6118/3978/5557/5985/5984/23649/5424/54107/5425/5111/6119/5427/5983/56655/5981 21 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-203927 MicroRNA (miRNA) biogenesis 21/4699 24/10654 1.3226140431357803e-5 3.464459172691484e-5 1.4078099202270091e-5 5431/5435/5433/5439/192669/29102/5438/54487/8575/26523/23405/5434/5436/5901/5432/27161/5440/5430/5441/192670/5437 21 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5627123 RHO GTPases activate PAKs 21/4699 24/10654 1.3226140431357803e-5 3.464459172691484e-5 1.4078099202270091e-5 2017/79784/4628/5062/5879/4638/4659/4771/801/5500/2316/10627/5063/998/5058/4660/4629/4627/10398/4637/103910 21 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-382556 ABC-family proteins mediated transport 67/4699 103/10654 1.3713158729544083e-5 3.585339824260688e-5 1.456930712812485e-5 5689/1965/5682/23/143471/5705/5709/5695/5711/5683/5699/5702/4363/5696/5691/7314/5718/5700/122706/5707/79139/91445/23198/9861/8894/5698/215/5692/5713/5710/5719/6233/1968/5243/6048/5706/10257/335/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10349/10197/5824/1244/7316/10213/7415/5715/5701/5825/5685/5686/5716/5693/5721 67 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-165159 mTOR signalling 31/4699 40/10654 1.7083983040729733e-5 4.458347990554749e-5 1.8116843686314842e-5 5563/53632/6198/29904/2475/55437/92335/84335/51422/7249/1981/5494/1977/1978/57521/28956/6194/64223/5571/6794/208/1975/55004/5562/5564/5565/7248/7529/207/8649/10542 31 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-3247509 Chromatin modifying enzymes 155/4699 274/10654 1.8104127110463097e-5 4.707073048720405e-5 1.912755729799415e-5 9643/9070/1810/4790/79718/64769/51742/79595/80314/10474/9112/10445/5929/79813/7403/54556/84289/9612/6603/5926/9767/27097/5928/1387/56950/3717/6907/23512/1107/79084/10943/6881/10499/1386/9575/55689/3054/51230/10284/55257/8089/54014/23774/8464/9869/6314/2648/23186/55869/2146/1788/51147/6871/23569/86/83933/5970/51562/64426/79685/8850/27154/57459/6604/8289/6602/55929/595/7994/8473/3066/23067/10419/8607/8726/6883/51780/10765/4791/55193/55904/84678/6595/1019/5927/29943/84148/7862/6597/9219/5931/8520/6599/11240/8819/11143/63976/1108/2122/84444/10524/55578/54815/23210/339287/55693/57504/58508/57634/6880/60/6601/6187/53615/10362/4297/121536/10196/8295/8841/55167/11091/8242/5978/8085/6839/25855/284058/6598/117143/10629/9611/2874/10856/29072/10933/80853/2033/6605/221656/3065/23028/23135/10498/9757/80854/51317/9739/10902/3276/55729/9913/8648/64754/10919 155 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-4839726 Chromatin organization 155/4699 274/10654 1.8104127110463097e-5 4.707073048720405e-5 1.912755729799415e-5 9643/9070/1810/4790/79718/64769/51742/79595/80314/10474/9112/10445/5929/79813/7403/54556/84289/9612/6603/5926/9767/27097/5928/1387/56950/3717/6907/23512/1107/79084/10943/6881/10499/1386/9575/55689/3054/51230/10284/55257/8089/54014/23774/8464/9869/6314/2648/23186/55869/2146/1788/51147/6871/23569/86/83933/5970/51562/64426/79685/8850/27154/57459/6604/8289/6602/55929/595/7994/8473/3066/23067/10419/8607/8726/6883/51780/10765/4791/55193/55904/84678/6595/1019/5927/29943/84148/7862/6597/9219/5931/8520/6599/11240/8819/11143/63976/1108/2122/84444/10524/55578/54815/23210/339287/55693/57504/58508/57634/6880/60/6601/6187/53615/10362/4297/121536/10196/8295/8841/55167/11091/8242/5978/8085/6839/25855/284058/6598/117143/10629/9611/2874/10856/29072/10933/80853/2033/6605/221656/3065/23028/23135/10498/9757/80854/51317/9739/10902/3276/55729/9913/8648/64754/10919 155 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5693532 DNA Double-Strand Break Repair 100/4699 166/10654 1.8495812842876373e-5 4.792052442970196e-5 1.9472877673488126e-5 2237/83990/151987/9156/1763/7486/5982/11200/472/6613/80198/3981/64421/4683/165918/84126/8900/8924/2067/672/6117/7334/10714/83695/55183/7314/6118/25/5888/51588/51720/63967/5531/116028/2070/890/9031/7517/9656/84464/5985/7157/5984/6233/7158/6047/5884/5810/5424/8467/80010/3838/7515/54107/51567/580/11073/5591/5425/641/5111/6119/3364/22976/10524/5427/144715/142/1111/7329/79728/51426/146956/7311/3980/5536/5983/2547/56655/51750/1017/54962/5893/5883/10111/7520/675/51548/545/7336/7316/8314/10635/7341/8914/5932/79184/7156/5599/5981 100 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-397795 G-protein beta:gamma signalling 26/4699 32/10654 1.8499233789813718e-5 4.792052442970196e-5 1.9472877673488126e-5 2788/2782/2787/10681/2792/10000/2785/2783/2784/2791/5170/998/695/2786/208/387/5058/54331/59345/207/9459/51764/94235/55970/2793/2790 26 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 16/4699 17/10654 2.012727026691711e-5 5.175583782921543e-5 2.1031387092093838e-5 356/929/8737/841/8797/8772/8717/8743/8837/8795/23643/7186/355/7099/353376/148022 16 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-432142 Platelet sensitization by LDL 16/4699 17/10654 2.012727026691711e-5 5.175583782921543e-5 2.1031387092093838e-5 5777/5526/5175/2268/1432/5518/5515/5528/5519/5781/338/5529/5516/5321/5525/5527 16 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5655862 Translesion synthesis by POLK 16/4699 17/10654 2.012727026691711e-5 5.175583782921543e-5 2.1031387092093838e-5 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/51426/7311/5983/7316/10459/5981 16 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5656121 Translesion synthesis by POLI 16/4699 17/10654 2.012727026691711e-5 5.175583782921543e-5 2.1031387092093838e-5 5982/6117/7314/6118/11201/51455/5985/5984/6233/5111/6119/7311/5983/7316/10459/5981 16 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-445717 Aquaporin-mediated transport 38/4699 52/10654 2.0985626410693542e-5 5.38643866190379e-5 2.1888212286338693e-5 2788/107/554/2782/2787/5567/10681/112/5573/111/2792/2785/2783/2784/196883/115/2791/5568/359/113/5566/2786/5577/109/54331/5575/59345/51764/94235/114/108/8766/55970/2778/2793/5576/551/2790 38 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1980143 Signaling by NOTCH1 50/4699 73/10654 2.1199156185642796e-5 5.431316657781476e-5 2.2070577511752586e-5 8454/79718/892/3091/23385/9978/9759/9612/4609/22938/1387/6907/408/83737/6868/9794/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/8650/1272/8850/3066/6233/5663/142678/409/10046/1024/10014/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 50 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-186763 Downstream signal transduction 24/4699 29/10654 2.191275215876559e-5 5.6039169455203806e-5 2.277195220027025e-5 5295/4893/5335/5291/6776/2885/8440/3845/3265/1399/5290/5921/6778/6714/6777/5781/6774/6772/5159/6654/4690/1398/5296/5156 24 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-202670 ERKs are inactivated 13/4699 13/10654 2.3679427971546807e-5 5.99025529226157e-5 2.4341868109205065e-5 1848/5518/51231/5515/1849/5594/5528/5519/5598/1846/5595/5516/1845 13 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-209543 p75NTR recruits signalling complexes 13/4699 13/10654 2.3679427971546807e-5 5.99025529226157e-5 2.4341868109205065e-5 8878/3654/3551/7314/8767/6233/7189/7311/4804/5584/4615/7316/4803 13 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-209560 NF-kB is activated and signals survival 13/4699 13/10654 2.3679427971546807e-5 5.99025529226157e-5 2.4341868109205065e-5 4790/8878/4792/3654/3551/7314/5970/6233/7189/7311/4804/7316/4803 13 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5140745 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 13/4699 13/10654 2.3679427971546807e-5 5.99025529226157e-5 2.4341868109205065e-5 1212/163/4920/2535/161/7474/1213/1211/7855/1175/1173/160/4919 13 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5357786 TNFR1-induced proapoptotic signaling 13/4699 13/10654 2.3679427971546807e-5 5.99025529226157e-5 2.4341868109205065e-5 7124/7375/1540/8737/841/7128/8772/8717/27005/7186/56957/7132/9099 13 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13/4699 13/10654 2.3679427971546807e-5 5.99025529226157e-5 2.4341868109205065e-5 7531/10971/7533/2810/11200/7465/7534/983/7532/891/1111/7529/995 13 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-3232118 SUMOylation of transcription factors 18/4699 20/10654 2.5334561645676763e-5 6.351736526880389e-5 2.5810775210445128e-5 9112/6613/7022/6612/4286/6670/51588/7157/7158/9063/8554/7020/1029/7329/7021/3090/7341/4193 18 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5627117 RHO GTPases Activate ROCKs 18/4699 20/10654 2.5334561645676763e-5 6.351736526880389e-5 2.5810775210445128e-5 388/79784/9475/4628/6093/1072/4659/389/5500/10627/387/5058/4660/4629/4627/10398/4637/103910 18 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654719 SHC-mediated cascade:FGFR4 18/4699 20/10654 2.5334561645676763e-5 6.351736526880389e-5 2.5810775210445128e-5 4893/9965/2264/2885/3845/3265/8823/8074/2249/2247/2246/2251/6464/6654/8817/2254/152831/26281 18 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654720 PI-3K cascade:FGFR4 18/4699 20/10654 2.5334561645676763e-5 6.351736526880389e-5 2.5810775210445128e-5 5295/9965/2264/2885/5290/8823/8074/2249/2247/2246/2251/5781/2549/8817/2254/152831/26281/10818 18 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69186 Lagging Strand Synthesis 18/4699 20/10654 2.5334561645676763e-5 6.351736526880389e-5 2.5810775210445128e-5 2237/1763/5982/5422/6117/10714/6118/3978/5557/5985/5984/23649/5424/5425/5111/6119/5983/5981 18 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8848021 Signaling by PTK6 39/4699 54/10654 2.572332862493507e-5 6.426255051496234e-5 2.6113587028872088e-5 4893/5770/9021/27043/3091/2064/5753/9542/3845/3265/5829/7314/5879/120892/2065/898/202559/5921/6421/595/6233/1019/10657/6774/2908/3084/10718/7311/2034/387/1956/1017/207/1027/7316/1950/867/2066/1398 39 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 39/4699 54/10654 2.572332862493507e-5 6.426255051496234e-5 2.6113587028872088e-5 4893/5770/9021/27043/3091/2064/5753/9542/3845/3265/5829/7314/5879/120892/2065/898/202559/5921/6421/595/6233/1019/10657/6774/2908/3084/10718/7311/2034/387/1956/1017/207/1027/7316/1950/867/2066/1398 39 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-389948 PD-1 signaling 20/4699 23/10654 2.6432605663967344e-5 6.580031622732296e-5 2.6738470081878128e-5 5777/3115/3113/3117/3127/5133/29126/1445/916/3932/5781/3120/3123/80380/3122/920/3119/919/915/917 20 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-428930 Thromboxane signalling through TP receptor 20/4699 23/10654 2.6432605663967344e-5 6.580031622732296e-5 2.6738470081878128e-5 2788/2769/2782/2776/2787/10681/2792/2785/2783/2784/2791/2786/54331/59345/51764/94235/55970/2793/9630/2790 20 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 27/4699 34/10654 2.7759279761818468e-5 6.873726417212192e-5 2.7931921713367882e-5 5431/5435/5433/5439/11198/904/51497/5438/1025/7936/6829/25920/2963/5434/5436/2962/5432/6917/5440/5430/6749/5441/7469/9150/5437/6827/8178 27 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 27/4699 34/10654 2.7759279761818468e-5 6.873726417212192e-5 2.7931921713367882e-5 5431/5435/5433/5439/11198/904/51497/5438/1025/7936/6829/25920/2963/5434/5436/2962/5432/6917/5440/5430/6749/5441/7469/9150/5437/6827/8178 27 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-4791275 Signaling by WNT in cancer 27/4699 34/10654 2.7759279761818468e-5 6.873726417212192e-5 2.7931921713367882e-5 27123/5526/1452/324/8312/5518/80351/5515/8322/5528/89780/5519/2932/4040/7855/4041/8658/6934/5529/5516/1487/1499/5525/139285/54894/5527/1488 27 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 40/4699 56/10654 3.099897079177149e-5 7.66242165345901e-5 3.113684612516707e-5 79718/5469/1387/6907/2101/84808/10499/23054/1386/85441/3054/7019/814/96764/23408/5465/64784/4208/6604/80205/6742/801/5442/3418/23410/4209/2553/2551/6648/23373/8841/200186/9611/23409/54205/6256/10498/1385/8648/10891 40 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-111933 Calmodulin induced events 28/4699 36/10654 3.942244336806221e-5 9.693364358801987e-5 3.9389739709631715e-5 817/5578/5582/107/814/818/5567/112/5573/111/5613/5580/196883/115/801/3838/5568/113/5566/816/5577/109/815/5575/114/108/5576/1385 28 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-111997 CaM pathway 28/4699 36/10654 3.942244336806221e-5 9.693364358801987e-5 3.9389739709631715e-5 817/5578/5582/107/814/818/5567/112/5573/111/5613/5580/196883/115/801/3838/5568/113/5566/816/5577/109/815/5575/114/108/5576/1385 28 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-156590 Glutathione conjugation 28/4699 36/10654 3.942244336806221e-5 9.693364358801987e-5 3.9389739709631715e-5 2938/2949/4259/27306/2944/4258/4257/124975/2940/2687/2686/221357/79017/373156/2729/2730/2954/9446/2946/2939/653689/2948/2947/2678/2937/119391/2941/2950 28 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-110312 Translesion synthesis by REV1 15/4699 16/10654 4.314215473275915e-5 1.0552540983413563e-4 4.288107072282315e-5 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/7311/5983/7316/10459/5981 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 15/4699 16/10654 4.314215473275915e-5 1.0552540983413563e-4 4.288107072282315e-5 5295/5291/2534/2885/9846/5290/5170/6464/2205/2206/6850/4067/6654/5296/2207 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 15/4699 16/10654 4.314215473275915e-5 1.0552540983413563e-4 4.288107072282315e-5 929/7314/257397/23118/10454/6233/3656/7189/7311/23643/6885/7099/7316/353376/148022 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-74752 Signaling by Insulin receptor 52/4699 78/10654 4.62595699329293e-5 1.1295380206231781e-4 4.5899655658851595e-5 5295/3643/4893/2250/5291/535/9965/2264/3630/2885/8660/9846/2252/3845/3265/54106/51606/5290/3667/8823/537/5594/8074/57761/2260/2249/2248/2247/2246/2251/5781/30849/5170/6464/527/2263/208/6654/2549/5595/8817/2254/152831/26281/10818/23545/2261/2255/27006/5296/51382/2887 52 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-429947 Deadenylation of mRNA 21/4699 25/10654 4.810462631473334e-5 1.1705181169130954e-4 4.7564913732710894e-5 26986/25904/1973/55571/57472/85456/29883/1981/1977/9924/5073/4850/255967/246175/4848/23019/1975/1974/4849/9337/9775 21 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9006115 Signaling by NTRK2 (TRKB) 21/4699 25/10654 4.810462631473334e-5 1.1705181169130954e-4 4.7564913732710894e-5 5295/627/4893/5335/2534/2885/3845/3265/5879/5290/6714/5781/6464/2904/7074/6654/2549/1020/4915/10818/8851 21 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-4086398 Ca2+ pathway 43/4699 62/10654 4.989046483886778e-5 1.211872190895681e-4 4.924536868087114e-5 2788/5578/27327/2775/5530/2782/192669/4343/3845/2787/2535/51701/8322/10681/2792/2785/2783/2784/7474/7855/26523/801/2791/4772/6934/2786/27161/815/54331/6885/1499/59345/5532/57690/51764/94235/192670/55970/2793/5534/23112/2790/5592 43 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9612973 Autophagy 74/4699 119/10654 5.030052666858714e-5 1.2197226155906106e-4 4.9564376791881165e-5 5563/65018/1459/1915/27243/9140/8878/1460/53632/5116/9474/8655/1457/51271/3043/3920/29082/55054/2475/84557/3312/11315/92421/7314/137492/64422/139341/25978/51160/9821/51422/7249/10533/10013/91782/79720/192111/6714/6233/9804/30849/57521/140735/28956/7405/79065/7416/26100/64223/5571/128866/3326/55004/7311/5562/93343/55626/7251/5564/5565/7248/10452/1080/64419/7316/83734/11152/8678/8649/3320/81631/10542/23710/7431 74 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-70326 Glucose metabolism 59/4699 91/10654 5.100133716491161e-5 1.234584092750619e-4 5.0168284470747907e-5 23165/7167/2806/8402/5211/348995/57122/6576/23511/23279/23225/9972/5518/2538/4191/8021/55746/5515/2597/5567/1468/10762/5528/2646/79902/5519/9883/8604/2645/6396/129401/230/5105/4928/5903/55706/7175/5568/2805/4927/5566/2023/4190/8086/5207/5516/81929/9631/5315/79023/23636/5214/53371/5230/10165/9688/5213/92579/8480 59 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-163615 PKA activation 17/4699 19/10654 5.2029373938377725e-5 1.2573019106623464e-4 5.109144066419192e-5 107/5567/112/5573/111/196883/115/801/5568/113/5566/5577/109/5575/114/108/5576 17 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-202427 Phosphorylation of CD3 and TCR zeta chains 19/4699 22/10654 5.2519177921097346e-5 1.264784319060389e-4 5.139549414685342e-5 5788/3115/3113/3117/55824/26191/3127/1445/916/3932/3120/3123/3122/920/5795/3119/919/915/917 19 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654712 FRS-mediated FGFR4 signaling 19/4699 22/10654 5.2519177921097346e-5 1.264784319060389e-4 5.139549414685342e-5 4893/9965/2264/2885/3845/3265/8823/8074/2249/2247/2246/2251/5781/6654/8817/2254/152831/26281/10818 19 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 29/4699 38/10654 5.355856593010091e-5 1.2815965242603814e-4 5.207867117627282e-5 759/5908/3313/6175/3181/4001/4282/5062/1072/6627/9049/27250/9987/3185/3458/5478/302/6775/9446/4478/998/6648/2939/6888/3586/829/6950/375/5721 29 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-190873 Gap junction degradation 12/4699 12/10654 5.3764982392404894e-5 1.2815965242603814e-4 5.207867117627282e-5 71/1212/1785/2697/1759/4646/1601/1213/1211/1173/8218/60 12 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-210990 PECAM1 interactions 12/4699 12/10654 5.3764982392404894e-5 1.2815965242603814e-4 5.207867117627282e-5 5777/5335/5175/2534/3690/3635/6714/7525/3685/3932/5781/4067 12 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-389359 CD28 dependent Vav1 pathway 12/4699 12/10654 5.3764982392404894e-5 1.2815965242603814e-4 5.207867117627282e-5 941/2534/2885/5062/5879/7409/3932/940/5063/998/5058/942 12 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 12/4699 12/10654 5.3764982392404894e-5 1.2815965242603814e-4 5.207867117627282e-5 7159/23368/8797/7157/8626/7161/8795/8793/3486/355/8794/124446 12 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9020558 Interleukin-2 signaling 12/4699 12/10654 5.3764982392404894e-5 1.2815965242603814e-4 5.207867117627282e-5 6776/3558/3718/3932/6777/6464/6850/3716/2185/3561/3560/3559 12 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6784531 tRNA processing in the nucleus 40/4699 57/10654 5.978310798755958e-5 1.4226353155005704e-4 5.780989211285869e-5 23165/348995/57122/23511/11260/23279/23225/9972/8021/51367/55746/60528/10940/10248/10762/1478/79902/9883/1653/6396/129401/4928/5903/55706/7175/4927/10898/5901/8086/81929/9631/29894/79023/23636/53371/10978/283742/9688/51493/8480 40 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 55/4699 84/10654 6.065134116268821e-5 1.4408541961491412e-4 5.855023049279012e-5 7124/1052/4790/79718/9441/892/5469/9612/1387/6907/4023/10499/23054/7040/85441/96764/7471/3952/5465/5970/6604/80205/9439/896/9370/9412/5105/1019/9440/6721/1051/1050/1024/9314/9968/51586/6517/80306/8841/5468/29079/6720/6837/688/9611/2033/9967/6256/10498/112950/27332/8202/8648/1959/10891 55 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-75153 Apoptotic execution phase 37/4699 52/10654 7.029644653944651e-5 1.6671657253611975e-4 6.77465754345306e-5 10059/836/324/9414/4001/3836/6709/6093/840/5062/2934/22985/63967/841/7082/5339/28988/10134/999/5588/5580/839/1828/5747/118/8428/1832/4000/3837/51765/1499/3146/329/4137/1677/7431/6304 37 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1368108 BMAL1:CLOCK,NPAS2 activates circadian gene expression 22/4699 27/10654 7.806648936057343e-5 1.8421067405419346e-4 7.485543959916993e-5 79718/28999/5469/1387/6907/10499/23054/9575/85441/96764/5054/10135/5465/6604/80205/406/8553/79365/6256/10498/8648/551 22 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-354192 Integrin alphaIIb beta3 signaling 22/4699 27/10654 7.806648936057343e-5 1.8421067405419346e-4 7.485543959916993e-5 5770/5908/2244/3690/2885/7094/6714/2335/1445/2266/2243/5170/6464/5747/3674/6850/6654/7450/207/54518/1398/5906 22 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9006921 Integrin signaling 22/4699 27/10654 7.806648936057343e-5 1.8421067405419346e-4 7.485543959916993e-5 5770/5908/2244/3690/2885/7094/6714/2335/1445/2266/2243/5170/6464/5747/3674/6850/6654/7450/207/54518/1398/5906 22 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1489509 DAG and IP3 signaling 31/4699 42/10654 8.91885997799857e-5 2.0975007385443873e-4 8.523357327118444e-5 5335/817/5578/5582/107/814/818/5567/112/5573/111/5613/5580/196883/115/801/3838/5568/113/5566/816/5577/109/815/5575/114/108/10768/5576/1385/5581 31 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 31/4699 42/10654 8.91885997799857e-5 2.0975007385443873e-4 8.523357327118444e-5 2788/2782/8826/2787/5567/10681/112/5573/111/2792/2785/2783/2784/2791/5568/5566/2641/2786/5577/54331/5575/59345/51764/94235/114/55970/2778/2793/5576/5906/2790 31 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 43/4699 63/10654 9.033393579053664e-5 2.1208837098647736e-4 8.618375849053135e-5 4790/5435/4792/3428/1387/22954/1660/3551/7314/11035/8737/29110/8517/6778/51428/5970/3661/6233/661/11128/4791/9533/3665/5434/7098/5591/7311/2547/1147/170506/5440/6737/1499/7520/5441/51082/4615/7316/55703/4793/5437/2033/148022 43 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8941326 RUNX2 regulates bone development 25/4699 32/10654 9.126536856564059e-5 2.139174915962594e-4 8.69270358713245e-5 5925/9759/10413/4089/3549/25/5594/3280/10013/2737/865/6714/7525/10432/4091/2736/367/860/5595/8841/23462/4086/4094/23314/25925 25 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-372708 p130Cas linkage to MAPK signaling for integrins 14/4699 15/10654 9.213475230765778e-5 2.1452270686559124e-4 8.717296980143234e-5 5908/2244/3690/7094/6714/2335/2266/2243/5747/3674/7450/54518/1398/5906 14 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-937039 IRAK1 recruits IKK complex 14/4699 15/10654 9.213475230765778e-5 2.1452270686559124e-4 8.717296980143234e-5 3654/7334/3551/7314/8517/6233/57162/7189/7311/1147/246330/7316/7335/57161 14 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 14/4699 15/10654 9.213475230765778e-5 2.1452270686559124e-4 8.717296980143234e-5 3654/51135/7334/7314/54106/6233/51311/3665/7189/7311/51284/4615/7316/7335 14 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 14/4699 15/10654 9.213475230765778e-5 2.1452270686559124e-4 8.717296980143234e-5 3654/7334/3551/7314/8517/6233/57162/7189/7311/1147/246330/7316/7335/57161 14 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-933542 TRAF6 mediated NF-kB activation 20/4699 24/10654 9.246493182701541e-5 2.149350402071683e-4 8.734052466058272e-5 4790/4792/177/3551/6283/4214/8517/5970/23586/4791/351/7706/7189/1147/7186/57506/4793/3146/6288/6285 20 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5693538 Homology Directed Repair 83/4699 138/10654 9.991274339778519e-5 2.3186362269502547e-4 9.421958577050818e-5 2237/83990/151987/9156/1763/7486/5982/472/6613/80198/4683/165918/84126/8900/8924/2067/672/6117/7334/10714/83695/7314/6118/25/5888/51588/51720/63967/5531/116028/890/7517/9656/84464/5985/5984/6233/7158/6047/5884/5810/5424/80010/7515/54107/580/11073/5425/641/5111/6119/3364/10524/5427/144715/142/1111/7329/79728/51426/146956/7311/3980/5983/56655/51750/1017/54962/5893/5883/10111/675/51548/545/7336/7316/10635/7341/8914/5932/79184/7156/5981 83 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 18/4699 21/10654 1.0369022032188833e-4 2.394425482433079e-4 9.729934109152264e-5 2237/5982/6117/10714/6118/328/3978/5985/5984/5424/54107/5425/5111/6119/5427/5983/56655/5981 18 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654688 SHC-mediated cascade:FGFR1 18/4699 21/10654 1.0369022032188833e-4 2.394425482433079e-4 9.729934109152264e-5 4893/2250/2885/3845/3265/8074/2260/2249/2248/2247/2246/2251/6464/6654/2254/26281/2255/27006 18 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654689 PI-3K cascade:FGFR1 18/4699 21/10654 1.0369022032188833e-4 2.394425482433079e-4 9.729934109152264e-5 5295/2250/2885/5290/8074/2260/2249/2248/2247/2246/2251/5781/2549/2254/26281/10818/2255/27006 18 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654221 Phospholipase C-mediated cascade; FGFR2 16/4699 18/10654 1.0627135319659972e-4 2.4419800309005897e-4 9.923175714110957e-5 2250/5335/2252/8823/8074/2249/2248/2247/2246/2251/2263/8817/2254/26281/2255/27006 16 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654704 SHC-mediated cascade:FGFR3 16/4699 18/10654 1.0627135319659972e-4 2.4419800309005897e-4 9.923175714110957e-5 4893/2250/2885/3845/3265/8823/8074/2249/2247/2246/6464/6654/8817/2254/26281/2261 16 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654710 PI-3K cascade:FGFR3 16/4699 18/10654 1.0627135319659972e-4 2.4419800309005897e-4 9.923175714110957e-5 5295/2250/2885/5290/8823/8074/2249/2247/2246/5781/2549/8817/2254/26281/10818/2261 16 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5218920 VEGFR2 mediated vascular permeability 23/4699 29/10654 1.1660398384094599e-4 2.6663191093271693e-4 1.0834795001164537e-4 857/2475/5062/5879/57761/1500/10000/3728/7409/801/253260/5170/64223/1003/5063/208/79109/5058/1495/1499/207/3320/4846 23 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8863795 Downregulation of ERBB2 signaling 23/4699 29/10654 1.1660398384094599e-4 2.6663191093271693e-4 1.0834795001164537e-4 26469/2064/4145/9542/7314/2065/10000/6233/5782/10193/3084/208/10718/7311/1956/11140/8065/10273/207/7316/1950/3320/2066 23 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-933541 TRAF6 mediated IRF7 activation 23/4699 29/10654 1.1660398384094599e-4 2.6663191093271693e-4 1.0834795001164537e-4 3443/1387/3445/29110/3444/23586/3451/3448/3661/3439/10010/3452/3446/3665/7706/3440/7189/3456/3441/7186/57506/3449/2033 23 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1059683 Interleukin-6 signaling 11/4699 11/10654 1.2206073114384904e-4 2.73759211702818e-4 1.1124418409276305e-4 9021/3717/3569/3572/3570/7297/5781/6774/6772/3716/867 11 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 11/4699 11/10654 1.2206073114384904e-4 2.73759211702818e-4 1.1124418409276305e-4 64344/3091/1387/25994/2056/405/768/10370/2034/7422/2033 11 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1236977 Endosomal/Vacuolar pathway 11/4699 11/10654 1.2206073114384904e-4 2.73759211702818e-4 1.1124418409276305e-4 3107/567/3106/3133/1515/1514/3135/4012/3105/1520/3134 11 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-196025 Formation of annular gap junctions 11/4699 11/10654 1.2206073114384904e-4 2.73759211702818e-4 1.1124418409276305e-4 71/1212/1785/2697/1759/1601/1213/1211/1173/8218/60 11 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2514853 Condensation of Prometaphase Chromosomes 11/4699 11/10654 1.2206073114384904e-4 2.73759211702818e-4 1.1124418409276305e-4 1459/1460/1457/64151/10051/983/23397/9133/891/10592/9918 11 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-3371378 Regulation by c-FLIP 11/4699 11/10654 1.2206073114384904e-4 2.73759211702818e-4 1.1124418409276305e-4 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355 11 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5218900 CASP8 activity is inhibited 11/4699 11/10654 1.2206073114384904e-4 2.73759211702818e-4 1.1124418409276305e-4 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355 11 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5655291 Signaling by FGFR4 in disease 11/4699 11/10654 1.2206073114384904e-4 2.73759211702818e-4 1.1124418409276305e-4 5295/4893/5335/2264/2885/3845/3265/5290/6654/2549/10818 11 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-68689 CDC6 association with the ORC:origin complex 11/4699 11/10654 1.2206073114384904e-4 2.73759211702818e-4 1.1124418409276305e-4 1869/84515/4998/990/5001/23594/4999/5000/1870/23595/1871 11 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69416 Dimerization of procaspase-8 11/4699 11/10654 1.2206073114384904e-4 2.73759211702818e-4 1.1124418409276305e-4 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355 11 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 11/4699 11/10654 1.2206073114384904e-4 2.73759211702818e-4 1.1124418409276305e-4 7314/257397/23118/10454/6233/7098/7189/7311/6885/7316/148022 11 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9614399 Regulation of localization of FOXO transcription factors 11/4699 11/10654 1.2206073114384904e-4 2.73759211702818e-4 1.1124418409276305e-4 2308/10971/2810/7534/10000/7532/4303/208/7529/2309/207 11 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-187687 Signalling to ERKs 26/4699 34/10654 1.244860731074418e-4 2.7875350341762087e-4 1.1327365336058669e-4 4893/5605/1432/5603/2885/3845/3265/1399/5594/9261/6714/4914/5600/6300/6464/673/7867/6654/5900/7529/5595/5604/10818/4803/1398/5906 26 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5619115 Disorders of transmembrane transporters 102/4699 176/10654 1.3649954247089172e-4 3.051677669253694e-4 1.2400729470201695e-4 23165/5689/5682/285195/348995/143471/57122/5705/23511/5709/5695/554/23279/5711/10999/23225/5683/5699/5702/9972/8021/55746/28234/5696/5691/6513/7314/5718/5700/122706/5707/79139/91445/23198/10762/2646/9861/79902/9883/5698/215/5692/5713/5710/8647/5719/6233/2645/6396/129401/4928/5903/55706/7175/116085/56606/6048/5706/19/335/5714/4927/5688/5687/5708/8086/6514/5704/7311/11160/5694/9197/81929/5684/5720/9631/5690/5717/9491/1080/79023/23636/10197/1244/7316/10213/53371/9688/7415/5715/5701/5685/682/5686/5716/213/5693/551/5721/6566/8480/10599 102 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-70171 Glycolysis 47/4699 71/10654 1.3802114969450324e-4 3.0807900504146665e-4 1.2519029894472557e-4 23165/7167/5211/348995/57122/23511/23279/23225/9972/5518/8021/55746/5515/2597/5567/10762/5528/2646/79902/5519/9883/2645/6396/129401/230/4928/5903/55706/7175/5568/4927/5566/2023/8086/5207/5516/81929/9631/5315/79023/23636/5214/53371/5230/9688/5213/8480 47 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-73887 Death Receptor Signalling 84/4699 141/10654 1.4469562072768819e-4 3.2246452619313367e-4 1.310359673089507e-4 7124/4790/7531/29/356/7375/9530/8878/1894/23385/4792/9138/836/10616/3654/6868/8997/8874/1540/3551/7314/5879/257397/9181/90268/81858/8737/8767/55072/23118/841/8517/6453/9828/5970/8797/7128/396/10454/3066/6233/7409/26574/8772/331/8717/8743/5663/572/7074/330/27005/50650/843/8837/8567/7189/6654/7311/387/8795/1147/4804/57142/8841/7186/56957/6885/5584/10018/8793/9459/355/23421/4615/9500/7316/50649/7132/329/9099/4803/3065/5599 84 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 21/4699 26/10654 1.4574404182511402e-4 3.242862673890017e-4 1.3177624600752659e-4 83990/9156/1763/7486/472/4683/672/5888/116028/7517/80010/580/641/10524/79728/51750/10111/675/10635/5932/7156 21 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-212165 Epigenetic regulation of gene expression 88/4699 149/10654 1.5604948475263304e-4 3.4666689334287464e-4 1.4087078736829965e-4 51742/79595/2074/29128/9112/11335/8932/5435/80312/5928/7913/1789/2965/23512/64425/1107/2967/23411/23378/10284/2648/2146/1788/30834/404672/26147/200424/9031/23309/4641/64426/79685/8850/2932/57459/2068/3066/54790/8726/9533/8467/5252/5434/9015/10514/79101/9219/1786/29115/5931/221830/8819/7270/4331/9013/1108/2966/29947/11176/54815/3720/2071/10849/57504/6908/60/25942/53615/121536/23451/5440/902/6839/9014/25885/5441/51082/6996/7343/5437/2033/3065/2968/84172/22823/1022/10919/9188 88 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654687 Downstream signaling of activated FGFR1 24/4699 31/10654 1.6359373916166627e-4 3.628524641121318e-4 1.4744791988962022e-4 5295/4893/2250/5335/2885/3845/3265/5290/8074/2260/2249/2248/2247/2246/2251/5781/6464/6654/2549/2254/26281/10818/2255/27006 24 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654693 FRS-mediated FGFR1 signaling 19/4699 23/10654 1.7643039614246385e-4 3.907070602271597e-4 1.5876685158428593e-4 4893/2250/2885/3845/3265/8074/2260/2249/2248/2247/2246/2251/5781/6654/2254/26281/10818/2255/27006 19 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 79/4699 132/10654 1.8283796292514686e-4 4.042590550344979e-4 1.6427381003801013e-4 83990/151987/9156/1763/7486/5982/472/6613/80198/4683/165918/84126/8900/8924/2067/672/6117/7334/10714/83695/7314/6118/25/5888/51588/51720/63967/5531/116028/890/7517/9656/84464/5985/5984/6233/7158/6047/5884/5810/5424/80010/54107/580/11073/5425/641/5111/6119/3364/10524/5427/144715/1111/7329/79728/51426/146956/7311/5983/56655/51750/1017/54962/5893/5883/10111/675/51548/545/7336/7316/10635/7341/8914/5932/79184/7156/5981 79 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2172127 DAP12 interactions 31/4699 43/10654 1.8476652083706139e-4 4.078808101497393e-4 1.6574553838743342e-4 5295/3810/4893/5335/7305/5291/3824/567/2534/3822/2885/3133/3845/3265/5879/5290/5336/3806/3932/6464/3937/3813/6850/9436/22914/695/6654/9402/100132285/27040/5296 31 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8852135 Protein ubiquitination 51/4699 79/10654 1.9041863845664815e-4 4.19698223537102e-4 1.705476361951637e-4 11065/257218/7321/56852/65264/8239/55236/56254/3093/7347/7328/7334/7332/80349/7314/90268/79139/10477/92912/7323/29089/7324/6233/23168/7874/6596/123169/9646/79577/7326/5591/7317/8915/5111/9810/118424/5830/7327/7311/3105/997/7319/7320/7336/7316/54926/7415/7322/54623/55284/27338 51 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-201681 TCF dependent signaling in response to WNT 130/4699 233/10654 1.9136954625425233e-4 4.2113298266609764e-4 1.7113066172216596e-4 27123/9070/5689/857/7478/5682/1459/5526/1452/5929/1460/143471/5705/6657/8452/55366/5709/9978/5695/1457/4609/5711/1387/5683/324/5699/8312/5702/1855/90780/5518/25776/6659/80351/5696/5691/7314/5515/5718/8945/2535/6662/5700/122706/5707/1856/1454/8322/23198/7471/7534/5528/89780/59349/9861/81847/5519/2932/8321/9580/5698/5692/5713/5710/8313/5719/6233/7474/1857/7514/4040/7479/7855/331/8607/4221/123169/6597/864/10023/4041/79577/6736/5706/23401/8658/5714/6934/10524/5688/5687/5708/5529/208/57680/5704/7311/5694/5516/5684/8295/5720/7015/1487/1499/5525/139285/207/8085/5690/5717/9491/10197/64750/7316/10213/5715/5701/1455/5685/5686/2033/54894/3065/5527/5716/23072/5693/5721/6259 130 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-162594 Early Phase of HIV Life Cycle 13/4699 14/10654 1.9595110510877965e-4 4.252169266966409e-4 1.7279020413073877e-4 2237/7852/3981/3836/3978/11168/5478/920/2547/1234/3159/7520/8815 13 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 13/4699 14/10654 1.9595110510877965e-4 4.252169266966409e-4 1.7279020413073877e-4 5861/2801/5594/983/8548/8615/9133/891/5347/5595/5862/26003/64689 13 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-170670 Adenylate cyclase inhibitory pathway 13/4699 14/10654 1.9595110510877965e-4 4.252169266966409e-4 1.7279020413073877e-4 2770/107/2773/112/111/2771/196883/115/113/109/114/108/346562 13 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-177504 Retrograde neurotrophin signalling 13/4699 14/10654 1.9595110510877965e-4 4.252169266966409e-4 1.7279020413073877e-4 1785/6456/163/1759/161/4914/1213/1211/1175/1173/160/26052/4803 13 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-3371568 Attenuation phase 13/4699 14/10654 1.9595110510877965e-4 4.252169266966409e-4 1.7279020413073877e-4 3305/1387/3306/3312/3303/3337/3297/3326/3304/10728/3320/2033/2288 13 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 13/4699 14/10654 1.9595110510877965e-4 4.252169266966409e-4 1.7279020413073877e-4 4436/9156/6117/10714/6118/3978/5424/2956/4292/5425/5111/6119/5395 13 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 13/4699 14/10654 1.9595110510877965e-4 4.252169266966409e-4 1.7279020413073877e-4 79370/7159/23368/332/64065/7157/604/5875/8626/7161/10397/9540/5876 13 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8941856 RUNX3 regulates NOTCH signaling 13/4699 14/10654 1.9595110510877965e-4 4.252169266966409e-4 1.7279020413073877e-4 22938/1387/9794/2648/55534/3280/84441/8850/864/10046/4851/2033/3516 13 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9027284 Erythropoietin activates RAS 13/4699 14/10654 1.9595110510877965e-4 4.252169266966409e-4 1.7279020413073877e-4 4893/3717/2885/2056/8660/3845/3265/1399/2057/7409/6464/4067/6654 13 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-418217 G beta:gamma signalling through PLC beta 17/4699 20/10654 2.032999769303481e-4 4.3912795016955196e-4 1.7844305667408697e-4 2788/2782/2787/10681/2792/2785/2783/2784/2791/2786/54331/59345/51764/94235/55970/2793/2790 17 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654706 FRS-mediated FGFR3 signaling 17/4699 20/10654 2.032999769303481e-4 4.3912795016955196e-4 1.7844305667408697e-4 4893/2250/2885/3845/3265/8823/8074/2249/2247/2246/5781/6654/8817/2254/26281/10818/2261 17 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 17/4699 20/10654 2.032999769303481e-4 4.3912795016955196e-4 1.7844305667408697e-4 22938/1387/4088/4853/9794/2648/55534/3280/84441/8850/10046/59/4855/4851/23462/2033/3516 17 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 22/4699 28/10654 2.1212879828416906e-4 4.574943668064107e-4 1.8590639286930174e-4 10381/10576/7846/81027/10574/10693/5204/10575/10471/84617/10382/7277/10383/60/84790/22948/7280/10694/5203/7203/908/6950 22 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2033519 Activated point mutants of FGFR2 15/4699 17/10654 2.157537882265747e-4 4.624707155268868e-4 1.8792857086187786e-4 2250/2252/8823/8074/2249/2248/2247/2246/2251/2263/8817/2254/26281/2255/27006 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-4655427 SUMOylation of DNA methylation proteins 15/4699 17/10654 2.157537882265747e-4 4.624707155268868e-4 1.8792857086187786e-4 1912/6045/80012/1911/1789/57332/1788/84733/7703/6015/8535/1786/7329/648/7341 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 15/4699 17/10654 2.157537882265747e-4 4.624707155268868e-4 1.8792857086187786e-4 929/7314/257397/23118/10454/6233/3656/7189/7311/23643/6885/7099/7316/353376/148022 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 15/4699 17/10654 2.157537882265747e-4 4.624707155268868e-4 1.8792857086187786e-4 2308/857/2290/57060/4089/1647/4088/5934/4303/901/9314/4087/2309/1027/1026 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2871809 FCERI mediated Ca+2 mobilization 25/4699 33/10654 2.185992539116852e-4 4.678557202622043e-4 1.9011680940329492e-4 5335/5530/2885/4773/5336/7409/3702/801/6464/2205/4772/3937/4775/2206/6850/4067/695/6654/7006/9402/5532/10768/27040/5534/2207 25 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-112043 PLC beta mediated events 37/4699 54/10654 2.4577256418880066e-4 5.252126029240124e-4 2.1342422460999752e-4 2770/817/5578/5582/2775/107/814/2773/818/5567/5594/112/5573/111/5613/2771/5580/196883/115/801/3838/2781/5568/113/5566/816/5577/109/815/5321/5575/114/108/10768/346562/5576/1385 37 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9024446 NR1H2 and NR1H3-mediated signaling 33/4699 47/10654 2.598863025261404e-4 5.545294357852601e-4 2.2533734757505694e-4 79718/27327/9612/6907/192669/4343/1071/10062/5360/348/6257/26523/29116/5105/6319/19/27161/8841/347/8204/57690/6720/192670/9611/2874/2194/2033/221656/23028/6256/23112/7376/8648 33 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1643713 Signaling by EGFR in Cancer 20/4699 25/10654 2.6990615387614293e-4 5.732953707142279e-4 2.3296303113443665e-4 5295/374/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 20 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 20/4699 25/10654 2.6990615387614293e-4 5.732953707142279e-4 2.3296303113443665e-4 51807/10381/10576/7846/81027/10574/10693/10575/10376/84617/10382/7277/10383/84790/22948/7280/10694/7203/908/6950 20 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8854691 Interleukin-20 family signaling 20/4699 25/10654 2.6990615387614293e-4 5.732953707142279e-4 2.3296303113443665e-4 11009/6776/3717/3588/3718/6777/6773/7297/5781/6775/50616/53833/6774/6772/29949/116379/163702/3716/58985/53832 20 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-110056 MAPK3 (ERK1) activation 10/4699 10/10654 2.770770787577583e-4 5.797559144201083e-4 2.3558832329861955e-4 3717/3569/3572/983/3570/7297/5781/3716/5595/5604 10 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 10/4699 10/10654 2.770770787577583e-4 5.797559144201083e-4 2.3558832329861955e-4 5563/53632/1432/51422/5600/6300/5571/5564/5565/10891 10 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-381183 ATF6 (ATF6-alpha) activates chaperone genes 10/4699 10/10654 2.770770787577583e-4 5.797559144201083e-4 2.3558832329861955e-4 811/3309/4801/468/7184/7494/4800/22926/4802/1649 10 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-390450 Folding of actin by CCT/TriC 10/4699 10/10654 2.770770787577583e-4 5.797559144201083e-4 2.3558832329861955e-4 10576/10574/10693/10575/60/22948/10694/7203/908/6950 10 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-450341 Activation of the AP-1 family of transcription factors 10/4699 10/10654 2.770770787577583e-4 5.797559144201083e-4 2.3558832329861955e-4 3725/1432/1386/5601/5594/2353/5600/5602/5595/5599 10 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-74749 Signal attenuation 10/4699 10/10654 2.770770787577583e-4 5.797559144201083e-4 2.3558832329861955e-4 3643/3630/2885/8660/3667/5594/6464/6654/5595/2887 10 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8853334 Signaling by FGFR3 fusions in cancer 10/4699 10/10654 2.770770787577583e-4 5.797559144201083e-4 2.3558832329861955e-4 5295/4893/2885/3845/3265/5290/6654/2549/10818/2261 10 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9020958 Interleukin-21 signaling 10/4699 10/10654 2.770770787577583e-4 5.797559144201083e-4 2.3558832329861955e-4 6776/50615/3718/6777/59067/6775/6774/6772/3716/3561 10 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-937042 IRAK2 mediated activation of TAK1 complex 10/4699 10/10654 2.770770787577583e-4 5.797559144201083e-4 2.3558832329861955e-4 7314/257397/23118/10454/6233/3656/7189/7311/6885/7316 10 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 10/4699 10/10654 2.770770787577583e-4 5.797559144201083e-4 2.3558832329861955e-4 2308/7295/1387/10628/23411/8850/4303/23410/2309/2033 10 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-422356 Regulation of insulin secretion 50/4699 78/10654 2.83264701726153e-4 5.918208946778554e-4 2.4049102182890813e-4 2788/6804/2770/5578/2769/2782/3630/2776/8826/2181/6513/2787/5567/784/10681/112/5573/111/2792/2785/2783/2784/2771/6844/2182/2791/5568/150/5566/775/2641/6514/2786/5577/6812/54331/5575/59345/51764/94235/114/55970/2778/10768/152/2793/5576/5906/9630/2790 50 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-157118 Signaling by NOTCH 130/4699 235/10654 3.1269991650733654e-4 6.52348711406093e-4 2.650869707468154e-4 8454/5689/3725/79718/5682/892/4904/27327/3091/23385/5705/5709/9978/1869/5695/9759/9612/4609/22938/5711/1387/4088/6907/5683/408/5699/4853/5702/192669/83737/6868/9794/4343/9787/5696/5691/7314/5718/23286/79885/2648/9734/7027/55869/5700/5707/51564/55534/3280/84441/10013/7534/83933/4854/3714/8650/1272/10320/9861/5870/8850/5087/5698/5692/5713/595/5710/3002/3066/7157/5719/6233/26523/5663/4192/142678/409/5706/10046/1024/5714/6772/10014/5688/5687/5708/59/4855/5704/7311/1956/5694/4851/27161/5684/8841/2208/5720/5584/23462/207/5690/57690/5717/9491/6500/51548/10197/192670/488/7316/10213/1950/9611/1871/5715/5701/5685/5686/2033/55294/3065/861/2683/23112/5716/1385/3516/5693/5721 130 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1250196 SHC1 events in ERBB2 signaling 18/4699 22/10654 3.3395991112544873e-4 6.95667233264288e-4 2.826897888958195e-4 4893/5578/2064/9542/2885/3845/3265/2065/5580/6464/5782/3084/6654/10718/1956/1950/2066/5581 18 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 27/4699 37/10654 3.498875252085373e-4 7.277660524337577e-4 2.9573339362655324e-4 79718/27327/9612/6907/192669/4343/1071/10062/5360/348/6257/26523/19/27161/8841/347/57690/192670/9611/2874/2033/221656/23028/6256/23112/7376/8648 27 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 24/4699 32/10654 3.8057885094974514e-4 7.892654456919381e-4 3.207241502211955e-4 51807/10381/10576/7846/81027/10574/10693/5204/10575/10471/10376/84617/10382/7277/10383/60/84790/22948/7280/10694/5203/7203/908/6950 24 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5626467 RHO GTPases activate IQGAPs 24/4699 32/10654 3.8057885094974514e-4 7.892654456919381e-4 3.207241502211955e-4 71/6249/51807/347688/10381/7846/81027/8826/5879/999/10376/801/4221/84617/10382/7277/998/10788/10383/60/84790/7280/1495/1499 24 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-202430 Translocation of ZAP-70 to Immunological synapse 16/4699 19/10654 3.955619092404514e-4 8.19128201435979e-4 3.328591131941076e-4 3115/3113/3117/26191/3127/916/3932/3120/3123/3122/920/7535/3119/919/915/917 16 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 12/4699 13/10654 4.14791635442701e-4 8.551651338642469e-4 3.475030008655135e-4 2064/9542/7314/2065/10000/6233/10193/3084/208/7311/207/7316 12 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1679131 Trafficking and processing of endosomal TLR 12/4699 13/10654 4.14791635442701e-4 8.551651338642469e-4 3.475030008655135e-4 54106/1515/51311/1508/1514/7184/7098/81622/51284/1513/5641/1520 12 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-879415 Advanced glycosylation endproduct receptor signaling 12/4699 13/10654 4.14791635442701e-4 8.551651338642469e-4 3.475030008655135e-4 177/6283/5594/351/1650/830/3958/829/5595/3146/6288/6285 12 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-977444 GABA B receptor activation 28/4699 39/10654 4.2449713413987604e-4 8.72611971204079e-4 3.545926588638558e-4 2788/2770/2550/107/9568/2782/2773/2787/112/111/2792/2785/2783/2784/2771/196883/115/113/2786/109/54331/94235/114/108/55970/346562/2793/2790 28 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-991365 Activation of GABAB receptors 28/4699 39/10654 4.2449713413987604e-4 8.72611971204079e-4 3.545926588638558e-4 2788/2770/2550/107/9568/2782/2773/2787/112/111/2792/2785/2783/2784/2771/196883/115/113/2786/109/54331/94235/114/108/55970/346562/2793/2790 28 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-112040 G-protein mediated events 37/4699 55/10654 4.333029442989186e-4 8.891651254818888e-4 3.6131916180175724e-4 2770/817/5578/5582/2775/107/814/2773/818/5567/5594/112/5573/111/5613/2771/5580/196883/115/801/3838/2781/5568/113/5566/816/5577/109/815/5321/5575/114/108/10768/346562/5576/1385 37 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1433559 Regulation of KIT signaling 14/4699 16/10654 4.350829353319499e-4 8.891651254818888e-4 3.6131916180175724e-4 5777/5578/2534/2885/3815/9306/6714/7525/3932/10019/8651/4067/6654/867 14 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-156711 Polo-like kinase mediated events 14/4699 16/10654 4.350829353319499e-4 8.891651254818888e-4 3.6131916180175724e-4 5928/7465/993/2305/9133/286826/891/55957/5347/4605/1063/9088/2033/995 14 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-429958 mRNA decay by 3' to 5' exoribonuclease 14/4699 16/10654 4.350829353319499e-4 8.891651254818888e-4 3.6131916180175724e-4 5393/23404/28960/10767/11340/80349/23016/118460/51010/56915/22894/51013/6499/54512 14 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-452723 Transcriptional regulation of pluripotent stem cells 19/4699 24/10654 4.954991605411667e-4 0.0010111639845927296 4.108943467155942e-4 6299/64344/79727/6657/55211/4089/2516/5460/5087/2247/6774/9314/79923/4087/2034/7547/6997/27086/57167 19 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8853659 RET signaling 29/4699 41/10654 5.038899163578816e-4 0.001026794546540589 4.172459470872689e-4 5295/2674/5335/5291/5578/2668/2885/8660/9846/5290/5567/6714/5598/9260/5781/6464/5568/5566/8503/6654/5293/2549/85358/5909/10818/5979/5296/2887/9046 29 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1632852 Macroautophagy 58/4699 95/10654 6.264863598053419e-4 0.0012732338426814623 5.173884710851347e-4 5563/65018/1459/27243/9140/8878/1460/53632/9474/8655/1457/29082/55054/2475/84557/3312/92421/7314/64422/139341/25978/9821/51422/7249/10533/91782/192111/6714/6233/9804/30849/57521/140735/28956/7405/79065/7416/26100/64223/5571/128866/55004/7311/5562/55626/5564/5565/7248/10452/64419/7316/83734/11152/8678/8649/81631/10542/23710 58 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-500657 Presynaptic function of Kainate receptors 17/4699 21/10654 6.266414425163037e-4 0.0012732338426814623 5.173884710851347e-4 2788/2782/2787/10681/2792/2785/2783/2784/2791/2786/54331/59345/51764/94235/55970/2793/2790 17 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-182971 EGFR downregulation 23/4699 31/10654 6.565434488547282e-4 0.0013320621418960092 5.412938078479811e-4 374/6456/30011/2885/8874/7314/8027/2060/9146/6455/6233/29924/5782/998/7311/1956/10253/58513/7316/1950/867/10254/6457 23 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 15/4699 18/10654 7.631659633764485e-4 0.0015417050540727103 6.264838351382585e-4 5295/11052/613/6776/11064/2885/9846/7750/8805/26127/5290/399687/6777/6774/6772 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 15/4699 18/10654 7.631659633764485e-4 0.0015417050540727103 6.264838351382585e-4 4893/5578/2885/6196/6197/3845/3265/5594/5598/6195/6654/1956/5595/4314/1385 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 15/4699 18/10654 7.631659633764485e-4 0.0015417050540727103 6.264838351382585e-4 929/7187/7314/29110/3661/6233/10010/5781/3665/7311/23643/7099/7316/353376/148022 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1236394 Signaling by ERBB4 38/4699 58/10654 8.028069204054655e-4 0.0016194553394386112 6.580782680879648e-4 5295/4893/51741/23385/6776/4734/10413/83737/6868/9542/2885/3845/3265/7314/6387/5290/2065/23118/348/11059/6714/2099/2567/3925/6233/5663/6464/5241/3084/6654/10718/7311/1956/7316/1950/9611/2066/6285 38 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 70/4699 119/10654 8.260938825666585e-4 0.001664039901181619 6.761955513873427e-4 79718/9441/892/1543/5469/9612/11010/1387/6907/2101/4801/2274/10499/23054/9575/1581/85441/10062/7296/96764/57761/5465/2222/6667/23309/336/3156/6604/80205/9439/4199/2168/183/6257/9412/405/1374/9440/6721/51/406/19/335/4800/1024/9968/9971/25942/51586/6095/80306/8841/5468/29079/4802/6720/6837/9611/2874/2033/9967/6256/7376/10498/112950/196/4520/8202/8648/10891 70 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1170546 Prolactin receptor signaling 13/4699 15/10654 8.707573983160729e-4 0.0017318260031684613 7.037409609516464e-4 8454/6776/9978/3717/5618/8945/2690/5617/6777/5781/2689/6500/2688 13 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5358508 Mismatch Repair 13/4699 15/10654 8.707573983160729e-4 0.0017318260031684613 7.037409609516464e-4 4436/9156/6117/10714/6118/3978/5424/2956/4292/5425/5111/6119/5395 13 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5654228 Phospholipase C-mediated cascade; FGFR4 13/4699 15/10654 8.707573983160729e-4 0.0017318260031684613 7.037409609516464e-4 5335/9965/2264/8823/8074/2249/2247/2246/2251/8817/2254/152831/26281 13 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69183 Processive synthesis on the lagging strand 13/4699 15/10654 8.707573983160729e-4 0.0017318260031684613 7.037409609516464e-4 2237/1763/5422/6117/10714/6118/3978/5557/23649/5424/5425/5111/6119 13 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-170968 Frs2-mediated activation 11/4699 12/10654 8.733139674097369e-4 0.0017318260031684613 7.037409609516464e-4 5605/1399/5594/4914/673/7529/5595/5604/10818/4803/5906 11 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2029481 FCGR activation 11/4699 12/10654 8.733139674097369e-4 0.0017318260031684613 7.037409609516464e-4 2268/2534/6714/7525/2214/2209/6850/4067/919/3055/917 11 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2197563 NOTCH2 intracellular domain regulates transcription 11/4699 12/10654 8.733139674097369e-4 0.0017318260031684613 7.037409609516464e-4 4853/9794/55534/3280/84441/3002/10046/2208/2033/1385/3516 11 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-264870 Caspase-mediated cleavage of cytoskeletal proteins 11/4699 12/10654 8.733139674097369e-4 0.0017318260031684613 7.037409609516464e-4 836/6709/840/2934/841/5339/28988/839/118/4137/7431 11 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-3371511 HSF1 activation 11/4699 12/10654 8.733139674097369e-4 0.0017318260031684613 7.037409609516464e-4 7531/1915/6117/6118/10013/3297/6119/3326/10728/7415/3320 11 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8984722 Interleukin-35 Signalling 11/4699 12/10654 8.733139674097369e-4 0.0017318260031684613 7.037409609516464e-4 3717/3572/3592/7297/6775/3595/821/6774/6772/3716/9466 11 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 11/4699 12/10654 8.733139674097369e-4 0.0017318260031684613 7.037409609516464e-4 7187/7314/29110/3661/6233/10010/3665/7098/7311/7316/148022 11 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-167044 Signalling to RAS 16/4699 20/10654 0.0011646096384808622 0.0023062227537759246 9.371515463686845e-4 4893/1432/5603/2885/3845/3265/9261/6714/4914/5600/6300/6464/7867/6654/5900/4803 16 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 19/4699 25/10654 0.001209877014980409 0.002392489195820415 9.7220658579597e-4 22938/1387/9794/9787/23286/2648/55534/3280/84441/4854/10320/8850/5087/10046/6772/4851/23462/2033/3516 19 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-73933 Resolution of Abasic Sites (AP sites) 27/4699 39/10654 0.0013259079333952206 0.0026182485773373976 0.0010639456657046556 2237/4913/5982/6117/10714/6118/328/3978/5985/5984/4595/5424/7515/54107/5425/5111/6119/5427/142/4968/3980/5983/56655/11284/6996/5981/7374 27 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 14/4699 17/10654 0.0014586189551570295 0.002872231434839368 0.0011671535745111244 4790/4792/1660/3551/11035/8737/8517/5970/4791/7098/1147/4615/4793/148022 14 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9034015 Signaling by NTRK3 (TRKC) 14/4699 17/10654 0.0014586189551570295 0.002872231434839368 0.0011671535745111244 5295/4893/5335/2885/3845/3265/5290/3667/6714/25920/5800/6464/6654/581 14 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-74158 RNA Polymerase III Transcription 28/4699 41/10654 0.001504753075935773 0.002954787858201154 0.0012007010190021187 4774/5435/9328/10302/9330/2972/2975/7702/661/11128/9533/5434/2971/9329/6621/6908/6619/4784/6618/5440/5451/6617/5441/51082/55703/5437/4782/6741 28 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-749476 RNA Polymerase III Abortive And Retractive Initiation 28/4699 41/10654 0.001504753075935773 0.002954787858201154 0.0012007010190021187 4774/5435/9328/10302/9330/2972/2975/7702/661/11128/9533/5434/2971/9329/6621/6908/6619/4784/6618/5440/5451/6617/5441/51082/55703/5437/4782/6741 28 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1989781 PPARA activates gene expression 68/4699 117/10654 0.0015162149132523408 0.002973136505874702 0.001208157134640942 79718/9441/892/1543/5469/9612/11010/1387/6907/2101/4801/2274/10499/23054/9575/1581/85441/10062/7296/96764/57761/5465/2222/6667/336/3156/6604/80205/9439/4199/2168/183/6257/9412/405/1374/9440/6721/51/406/19/335/4800/1024/9968/9971/51586/6095/80306/8841/5468/29079/4802/6720/6837/9611/2874/2033/9967/6256/7376/10498/112950/196/4520/8202/8648/10891 68 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5693537 Resolution of D-Loop Structures 24/4699 34/10654 0.0016105236916245378 0.0031536614547292203 0.001281514851149526 83990/9156/1763/7486/472/80198/4683/672/5888/116028/7517/84464/80010/580/641/10524/79728/146956/51750/10111/675/10635/5932/7156 24 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-169893 Prolonged ERK activation events 12/4699 14/10654 0.0017278348174462252 0.00333225286221772 0.0013540868580911715 5605/1399/5594/4914/673/7529/5595/5604/10818/4803/1398/5906 12 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-174411 Polymerase switching on the C-strand of the telomere 12/4699 14/10654 0.0017278348174462252 0.00333225286221772 0.0013540868580911715 5982/5422/10714/5557/5985/5984/23649/5424/5425/5111/5983/5981 12 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-190322 FGFR4 ligand binding and activation 12/4699 14/10654 0.0017278348174462252 0.00333225286221772 0.0013540868580911715 9965/2264/8823/8074/2249/2247/2246/2251/8817/2254/152831/26281 12 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase 12/4699 14/10654 0.0017278348174462252 0.00333225286221772 0.0013540868580911715 107/5567/5573/5613/801/5568/5566/5577/5575/114/5576/1385 12 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 12/4699 14/10654 0.0017278348174462252 0.00333225286221772 0.0013540868580911715 4436/9156/6117/10714/6118/3978/5424/4292/5425/5111/6119/5395 12 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69091 Polymerase switching 12/4699 14/10654 0.0017278348174462252 0.00333225286221772 0.0013540868580911715 5982/5422/10714/5557/5985/5984/23649/5424/5425/5111/5983/5981 12 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69109 Leading Strand Synthesis 12/4699 14/10654 0.0017278348174462252 0.00333225286221772 0.0013540868580911715 5982/5422/10714/5557/5985/5984/23649/5424/5425/5111/5983/5981 12 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-69166 Removal of the Flap Intermediate 12/4699 14/10654 0.0017278348174462252 0.00333225286221772 0.0013540868580911715 2237/1763/5422/6117/10714/6118/5557/23649/5424/5425/5111/6119 12 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8983432 Interleukin-15 signaling 12/4699 14/10654 0.0017278348174462252 0.00333225286221772 0.0013540868580911715 6776/2885/9846/3600/3718/6777/6464/6774/6654/3716/3561/3560 12 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 12/4699 14/10654 0.0017278348174462252 0.00333225286221772 0.0013540868580911715 79718/9612/6907/4204/814/801/5566/25942/8841/9611/2874/3065 12 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9005895 Pervasive developmental disorders 12/4699 14/10654 0.0017278348174462252 0.00333225286221772 0.0013540868580911715 79718/9612/6907/4204/814/801/5566/25942/8841/9611/2874/3065 12 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5693607 Processing of DNA double-strand break ends 58/4699 98/10654 0.0018257567312202866 0.0034809304465063455 0.0014145031504021889 83990/151987/9156/1763/7486/5982/472/6613/4683/165918/84126/8900/8924/672/6117/7334/83695/7314/6118/51588/51720/63967/5531/116028/890/9656/5985/5984/6233/7158/6047/5884/5810/80010/580/11073/641/6119/3364/10524/144715/1111/7329/7311/5983/1017/54962/5883/10111/51548/545/7336/7316/7341/8914/5932/79184/7156 58 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-174414 Processive synthesis on the C-strand of the telomere 10/4699 11/10654 0.0018272405548968495 0.0034809304465063455 0.0014145031504021889 2237/1763/6117/10714/6118/3978/5424/5425/5111/6119 10 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-211999 CYP2E1 reactions 10/4699 11/10654 0.0018272405548968495 0.0034809304465063455 0.0014145031504021889 1571/1565/1555/1559/1557/1558/1572/1548/29785/1553 10 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-2586552 Signaling by Leptin 10/4699 11/10654 0.0018272405548968495 0.0034809304465063455 0.0014145031504021889 3953/9021/6776/3717/8660/3667/3952/6777/5781/6774 10 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5603041 IRAK4 deficiency (TLR2/4) 10/4699 11/10654 0.0018272405548968495 0.0034809304465063455 0.0014145031504021889 10333/929/51135/7096/695/23643/7099/4615/114609/7097 10 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-77588 SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs 10/4699 11/10654 0.0018272405548968495 0.0034809304465063455 0.0014145031504021889 134353/6636/6635/7884/84967/6637/22916/4686/6634/6628 10 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8875555 MET activates RAP1 and RAC1 10/4699 11/10654 0.0018272405548968495 0.0034809304465063455 0.0014145031504021889 5908/3082/2885/1399/5879/85440/4233/2549/1398/5906 10 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8934903 Receptor Mediated Mitophagy 10/4699 11/10654 0.0018272405548968495 0.0034809304465063455 0.0014145031504021889 1459/9140/1460/9474/1457/84557/139341/192111/6714/81631 10 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 10/4699 11/10654 0.0018272405548968495 0.0034809304465063455 0.0014145031504021889 7314/257397/23118/80216/10454/6233/7189/7311/6885/7316 10 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9619483 Activation of AMPK downstream of NMDARs 21/4699 29/10654 0.0018961058980467356 0.0036072258548206187 0.0014658242714895603 5563/51807/347688/53632/10381/7846/81027/51422/10376/801/84617/10382/7277/5571/5562/10383/84790/5564/5565/7280/4137 21 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-983231 Factors involved in megakaryocyte development and platelet production 93/4699 168/10654 0.002047073260209902 0.003889162188544929 0.001580391292691072 3443/57572/51807/347688/10381/832/3043/10112/3717/7846/81027/11004/10749/2626/4097/7465/81930/5879/3445/25/30846/5868/23186/5567/29127/3444/5573/91768/3796/23414/3451/3448/89953/56992/10376/3066/7157/3439/3835/161882/3452/9493/3660/3446/9732/3831/84617/85440/10019/10382/5568/830/3832/7277/23303/2623/3659/5566/80005/2627/1062/3440/4602/998/7975/5577/10383/24137/60/25942/84790/84643/3456/1020/10362/7280/829/11216/1017/23468/3441/2624/5575/2625/3449/81928/3705/5576/547/3065/23028/3799/51317 93 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-8940973 RUNX2 regulates osteoblast differentiation 18/4699 24/10654 0.0021177671786332675 0.00401261149635777 0.0016305558787118846 5925/10413/25/5594/3280/10013/2737/865/6714/7525/367/860/5595/8841/23462/4094/23314/25925 18 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 18/4699 24/10654 0.0021177671786332675 0.00401261149635777 0.0016305558787118846 374/5594/10000/595/7514/2353/5747/208/1956/5595/596/2309/207/6722/1027/1950/2002/1385 18 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-110320 Translesion Synthesis by POLH 15/4699 19/10654 0.002141681166386434 0.004046999135405859 0.0016445295631953637 5982/25898/6117/7314/6118/5985/5984/6233/5111/6119/7311/5983/7316/7415/5981 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 15/4699 19/10654 0.002141681166386434 0.004046999135405859 0.0016445295631953637 1869/4609/5928/990/7027/7153/5934/993/286826/5111/1874/55957/4149/5933/3065 15 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 33/4699 51/10654 0.0023832902545004152 0.0044974993512346545 0.0018275938284369343 51807/347688/10381/1780/5048/8655/832/636/7846/81027/23299/5870/10376/10540/140735/84617/1783/10382/55860/830/7277/1639/51143/10383/84790/7280/829/1778/5321/5050/1781/10121/51560 33 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-5693568 Resolution of D-loop Structures through Holliday Junction Intermediates 23/4699 33/10654 0.0026250886045347736 0.004947146846666876 0.0020103115841156446 83990/9156/1763/7486/472/80198/4683/672/5888/116028/7517/84464/80010/580/641/10524/79728/146956/10111/675/10635/5932/7156 23 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-110373 Resolution of AP sites via the multiple-nucleotide patch replacement pathway 19/4699 26/10654 0.002637855005135062 0.0049645421276268455 0.0020173802917781906 2237/5982/6117/10714/6118/328/3978/5985/5984/5424/54107/5425/5111/6119/5427/142/5983/56655/5981 19 Human_immunodeficiency_virus_type_1_group_M_subtype_B R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 44/4699 72/10654 0.0026568276396284796 0.0049935555636390705 0.002029170127074806 8773/55763/5563/71/7531/51807/10971/347688/7533/2810/53632/10381/7846/81027/51552/5879/51422/4644/7534/4641/10376/6844/9882/801/84617/7532/10382/7277/5571/208/5867/4012/10383/60/84790/5564/5565/7280/7529/6517/4627/207/8766/6814 44 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 294/2027 309/10654 1.2118376038745798e-196 1.5911427738873233e-193 7.845053961924912e-194 8454/9354/57154/5718/197131/23352/5689/26224/8945/10293/51088/140460/5684/79754/6737/8065/64410/127544/114088/5720/11065/285231/221687/9666/84937/57531/142678/55070/5682/84708/246184/146330/55819/51320/93611/54850/7319/142686/8916/79791/26046/151636/5700/122706/7321/5707/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/8697/7320/5690/26235/10477/9817/10193/148581/9039/223082/92912/154881/5717/140739/25897/9491/23198/6500/6478/150726/390594/10533/81559/143471/144699/5706/140462/5705/26259/57674/10197/53339/154214/7336/200845/79876/26263/64750/51619/6477/9690/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/10213/5709/9604/9978/22888/5695/23304/7317/80196/114907/140456/64718/54926/4008/7335/84861/11059/55236/84085/55958/54620/4734/84078/7337/5714/26272/84676/27252/51444/7704/8651/3093/26118/222235/51433/9861/25831/7322/5715/64219/10489/5711/23327/9867/26249/140458/55905/5701/5688/55336/5687/26270/143279/51465/63893/89122/6502/23291/118424/5685/10616/5683/5698/5708/27246/5692/5686/89910/5713/55521/25898/9903/201456/55294/5699/26190/55008/7328/79654/5710/10422/84727/135892/7428/5702/22954/8453/401036/83737/51529/9040/90933/140461/7324/63891/5719/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/5704/6233/90135/56658/9870/51434/6468/26267/142685/5716/25847/90025/7327/10425/25793/51343/7311/26091/23295/6047/84541/7318/23194/51666/90293/131405/55175/55284/868/54461/9320/80204/136371/26232/29882/57520/26234/127247/27338/7334/92591/5930/11275/55182/5694/84961/4591/23014/29116/26268/92369/115290/90678/51725/140459/5693/5721/5696/997/23608/51676/55585/64320/5691/51132/84261/7325/57542/9820/55658/7314/996/10324/283807/140691/899 294 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-983169 Class I MHC mediated antigen processing & presentation 314/2027 371/10654 1.0299700959123805e-172 6.761753679664777e-170 3.3338505736111266e-170 8454/9354/57154/1147/3135/5718/197131/23352/5689/26224/8945/10293/51088/140460/5684/79754/6737/8065/64410/127544/114088/5720/11065/285231/221687/9666/653361/84937/57531/142678/55070/5682/84708/246184/146330/55819/51320/93611/54850/7319/142686/8916/79791/26046/151636/5700/3107/122706/7321/5707/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/8697/10484/7320/5690/26235/10477/9817/10193/148581/9039/223082/92912/154881/5717/140739/25897/9491/23198/6500/6478/150726/390594/10533/81559/2209/143471/144699/5706/140462/5705/26259/57674/10197/7099/53339/8517/154214/7336/200845/4615/79876/26263/64750/51619/6477/9690/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/10213/5709/9604/9978/22888/5695/23304/7317/80196/114907/140456/64718/54926/4008/7335/84861/11059/567/55236/84085/55958/54620/4734/84078/7337/5714/26272/84676/27252/51444/7704/8651/3106/3093/26118/222235/51433/9861/25831/7322/5715/64219/10489/5711/23327/9867/26249/140458/55905/5701/5688/55336/5687/26270/143279/51465/63893/89122/6502/23291/118424/5685/10616/5683/929/3309/5698/5708/27246/5692/5686/89910/5713/114609/55521/25898/9903/201456/55294/5699/26190/55008/7328/79654/5710/10422/84727/135892/7428/5702/22954/8453/401036/83737/51529/9040/695/90933/140461/7324/63891/5719/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/5704/6233/90135/56658/9870/51434/6468/26267/142685/5716/25847/90025/7327/10425/25793/51343/7311/26091/23295/6047/84541/3133/7318/23194/51666/90293/131405/55175/55284/3134/868/54461/9320/80204/136371/26232/29882/57520/26234/6396/127247/27338/7334/92591/5930/11275/55182/5694/84961/4591/3551/23014/29116/26268/92369/115290/90678/51725/140459/3105/5693/5721/5696/997/23608/51676/55585/64320/5691/51132/84261/7325/57542/9820/55658/7314/996/10324/283807/140691/899 314 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69620 Cell Cycle Checkpoints 234/2027 293/10654 1.800791139976426e-116 7.881462555963492e-114 3.885917723107025e-114 5718/1017/220134/4172/6118/5689/5905/55839/80010/11130/79682/9134/5684/5903/10403/5000/5720/83990/11065/54908/8318/6249/55143/5682/9156/246184/55055/23594/5883/25936/5525/9735/1763/7531/51512/1029/80776/1783/1058/5700/7486/122706/7321/5707/991/401541/79019/5526/10111/8317/348235/80152/8697/5690/9212/1063/51720/8379/5717/1027/3619/5982/9491/23198/63967/79172/898/7533/2810/147841/348995/23421/4173/11200/143471/545/79023/55920/5706/9133/472/57122/5705/79980/64105/10197/7336/6232/7534/332/580/1780/8881/11073/23122/5528/5048/1781/7316/10213/5709/4174/891/993/5695/5501/116028/890/57405/8655/4085/983/1026/84515/641/5714/4171/23279/55166/51433/9861/79902/4194/3796/5715/54821/9656/5519/4998/6119/5711/9183/3364/81565/7341/5701/10524/2491/5688/4683/1062/699/5687/10926/144715/5685/5683/5698/5708/5692/22919/5985/5686/5713/990/91687/1060/995/119504/79003/84126/5699/5529/4175/5710/51143/1111/5702/7157/8900/51529/5984/7324/83540/5719/64682/29945/10393/8924/11004/5704/6233/5527/51434/55388/5716/701/672/7514/5932/7158/23595/7311/9184/79184/5518/25906/54820/5347/57551/7156/84643/5983/6117/29882/6396/7334/5001/5694/23332/7465/25909/64946/9793/10726/5884/5810/81930/55746/5693/5721/140735/5696/4999/83695/5691/4176/7529/7314/996/4193/5515/1778/5516 234 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8951664 Neddylation 195/2027 234/10654 2.7628203989669765e-103 9.0689579596091e-101 4.4714066983281336e-101 8454/9318/5718/5689/26224/54165/8945/51088/140460/5684/79754/8065/64410/5720/285231/11091/23363/5682/64344/146330/80344/25879/80067/93611/54850/142686/79791/5700/122706/7321/5707/51665/9616/122769/9021/4738/5690/26235/9817/9039/154881/5717/140739/5929/9491/23198/6500/5931/150726/3091/390594/143471/144699/5706/140462/28952/5705/55827/26259/10197/53339/200845/332/26263/8452/8450/7323/9306/10517/89890/142689/7316/10213/5709/9978/5695/114907/140456/4008/84861/64708/84085/55958/54620/84078/5714/79016/26272/27252/7704/1643/26118/222235/10980/9861/54876/7322/5715/10489/5711/26249/140458/5701/5688/55336/5687/26270/1161/6502/23291/5685/5683/55832/5698/5708/1642/5692/10920/5686/5713/9903/201456/55294/5699/26190/79269/10238/5710/84727/10987/7428/5702/8453/401036/9040/140461/5719/79176/80176/8139/126433/10116/5704/26043/6233/90135/6468/2873/26267/26094/142685/5716/25793/7311/84541/23194/51666/2034/90293/55175/8533/54461/80204/136371/26232/26234/127247/92591/11275/5694/84961/23014/8816/26268/92369/115290/51725/140459/5693/5721/5696/51676/5691/84261/50813/57542/9820/7314/51514/10537/51138/10324/8451/283807/899 195 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-72163 mRNA Splicing - Major Pathway 167/2027 183/10654 2.5120342479019794e-102 6.596601934990598e-100 3.252423289388879e-100 10450/7536/10921/8449/22827/23451/53981/2963/6635/5434/5440/6633/220988/6432/8683/51691/6431/10084/6430/6632/51340/10283/6627/24148/10946/83443/27339/11051/9129/55696/23350/5430/79869/4904/5436/9879/51639/51585/10523/6428/11325/9128/57703/27258/3184/8106/25804/51690/29894/27238/55749/11017/51503/3178/6637/199746/23450/5441/3183/5438/85313/5431/9092/54883/5093/81608/5435/10594/4686/9785/8189/6625/5433/10713/51645/11338/1655/9343/3185/3190/1477/10978/9416/6626/11157/5546/22826/7307/285755/6429/1478/10772/57819/10181/2962/10898/22938/988/10236/5437/10250/6629/4670/23020/23658/10189/51362/9295/10465/84844/6631/10949/51692/55660/3181/5439/10421/11193/51729/1660/23283/9939/2521/3191/10285/9410/6638/57794/27316/6636/3187/1993/1665/10286/23524/56949/53938/6634/10914/5094/51593/9775/3192/9716/8896/6427/3312/8175/5356/6426/84950/3188/84991/10907/10291/5432/22916/56259/5725/1479/26121/11100/10992/55339/10262/6628/1994 167 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-72172 mRNA Splicing 168/2027 191/10654 8.42567340414545e-97 1.8438181966071628e-94 9.090858146577988e-95 10450/7536/10921/8449/22827/23451/53981/2963/6635/5434/5440/6633/220988/6432/8683/51691/6431/10084/6430/6632/51340/10283/6627/24148/10946/83443/27339/11051/9129/55696/23350/5430/79869/85437/4904/5436/9879/51639/51585/10523/6428/11325/9128/57703/27258/3184/8106/25804/51690/29894/27238/55749/11017/51503/3178/6637/199746/23450/5441/3183/5438/85313/5431/9092/54883/5093/81608/5435/10594/4686/9785/8189/6625/5433/10713/51645/11338/1655/9343/3185/3190/1477/10978/9416/6626/11157/5546/22826/7307/285755/6429/1478/10772/57819/10181/2962/10898/22938/988/10236/5437/10250/6629/4670/23020/23658/10189/51362/9295/10465/84844/6631/10949/51692/55660/3181/5439/10421/11193/51729/1660/23283/9939/2521/3191/10285/9410/6638/57794/27316/6636/3187/1993/1665/10286/23524/56949/53938/6634/10914/5094/51593/9775/3192/9716/8896/6427/3312/8175/5356/6426/84950/3188/84991/10907/10291/5432/22916/56259/5725/1479/26121/11100/10992/55339/10262/6628/1994 168 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2467813 Separation of Sister Chromatids 165/2027 190/10654 4.128492663304379e-93 7.743872667026643e-91 3.8180796811010427e-91 5718/220134/5689/5905/55839/11130/79682/5684/5903/10403/5720/11065/54908/6249/55143/5682/246184/55055/25936/5525/9735/80776/55869/1783/1058/5700/122706/7321/5707/991/401541/79019/5526/348235/80152/8697/5690/10382/9212/1063/8379/5717/3619/9491/23198/79172/10274/147841/23244/348995/23421/143471/79023/55920/5706/57122/5705/79980/64105/10735/10197/6232/332/23047/1780/8881/23122/5885/5528/5048/1781/7316/10213/5709/5695/5501/57405/8655/4085/5714/23279/55166/51433/9861/79902/3796/5715/54821/5519/5711/9183/81565/5701/2491/5688/1062/699/5687/7846/5685/5683/5698/5708/5692/22919/5686/5713/91687/1060/119504/79003/8243/9126/5699/5529/5710/51143/5702/51529/7324/83540/5719/64682/29945/10393/11004/9232/5704/6233/5527/9700/51434/5716/701/7514/7311/9184/5518/25906/54820/5347/113130/57551/84790/84643/29882/6396/5694/23332/25909/64946/9793/10726/81930/55746/5693/5721/140735/5696/5691/7314/996/5515/1778/5516 165 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2555396 Mitotic Metaphase and Anaphase 169/2027 202/10654 6.542782874247745e-90 1.0738342392359112e-87 5.294488773239952e-88 4000/5718/220134/5689/5905/55839/11130/26271/79682/5684/5903/10403/5720/11065/54908/6249/55143/5682/246184/55055/25936/5525/9735/80776/55869/1783/1058/5700/122706/7321/5707/991/401541/79019/5526/348235/80152/8697/5690/10382/9212/1063/8379/5717/3619/9491/23198/79172/10274/147841/23244/348995/23421/143471/79023/55920/5706/57122/5705/79980/64105/10735/10197/6232/332/7443/23047/1780/8881/23122/5885/5528/5048/1781/7316/10213/5709/5695/5501/57405/8655/4085/5714/23279/55166/51433/9861/79902/3796/5715/54821/5519/5711/9183/81565/5701/2491/5688/1062/699/5687/7846/5685/5683/5698/5708/5692/22919/5686/5713/91687/1060/119504/79003/8243/9126/5699/5529/5710/51143/5702/5520/51529/7324/83540/5719/64682/29945/10393/11004/9232/5704/6233/5527/9700/51434/5716/701/7514/7311/9184/5518/25906/54820/5347/113130/57551/84790/84643/29882/6396/5694/23332/25909/64946/9793/10726/81930/55746/5693/5721/140735/5696/5691/7314/996/5515/1778/5516 169 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-68882 Mitotic Anaphase 168/2027 201/10654 3.0788025756414387e-89 4.4916308686857876e-87 2.21457729125086e-87 4000/5718/220134/5689/5905/55839/11130/79682/5684/5903/10403/5720/11065/54908/6249/55143/5682/246184/55055/25936/5525/9735/80776/55869/1783/1058/5700/122706/7321/5707/991/401541/79019/5526/348235/80152/8697/5690/10382/9212/1063/8379/5717/3619/9491/23198/79172/10274/147841/23244/348995/23421/143471/79023/55920/5706/57122/5705/79980/64105/10735/10197/6232/332/7443/23047/1780/8881/23122/5885/5528/5048/1781/7316/10213/5709/5695/5501/57405/8655/4085/5714/23279/55166/51433/9861/79902/3796/5715/54821/5519/5711/9183/81565/5701/2491/5688/1062/699/5687/7846/5685/5683/5698/5708/5692/22919/5686/5713/91687/1060/119504/79003/8243/9126/5699/5529/5710/51143/5702/5520/51529/7324/83540/5719/64682/29945/10393/11004/9232/5704/6233/5527/9700/51434/5716/701/7514/7311/9184/5518/25906/54820/5347/113130/57551/84790/84643/29882/6396/5694/23332/25909/64946/9793/10726/81930/55746/5693/5721/140735/5696/5691/7314/996/5515/1778/5516 168 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 181/2027 244/10654 4.276323872240598e-80 5.614813244251906e-78 2.7683570330820713e-78 10450/7536/10921/8449/22827/23451/53981/7919/2963/6635/5434/5440/5903/6633/220988/6432/8683/51691/6431/10084/6430/6632/51340/10283/6627/24148/10946/83443/27339/11051/9129/55696/23350/5430/79869/85437/4904/5436/9879/51639/51585/10523/6428/11325/9128/57703/27258/3184/8106/25804/51690/29894/27238/55749/11017/51503/3178/6637/199746/23450/348995/79023/57122/5441/3183/5438/85313/10762/5431/9092/54883/5093/23511/81608/5435/10594/4686/9785/8189/6625/5433/10713/51645/11338/1655/9343/3185/3190/1477/10978/9416/6626/56339/11157/5546/22826/7307/285755/6429/1478/10772/57819/23279/10181/79902/2962/10898/22938/988/10236/5437/10250/6629/4670/23020/23658/10189/51362/9295/10465/84844/6631/10949/51692/55660/3181/5439/10421/11193/51729/1660/23283/9939/2521/1977/3191/10285/9410/6638/57794/27316/6636/3187/1993/1665/10286/23524/56949/53938/6634/10914/5094/51593/9775/3192/9716/6396/8896/6427/3312/8175/5356/6426/84950/3188/84991/10907/10291/5432/55746/22916/56259/5725/1479/26121/11100/10992/55339/10262/6628/1994 181 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69242 S Phase 138/2027 161/10654 3.3657700919919396e-76 4.017505573441288e-74 1.980812063708175e-74 8454/5718/1017/4172/6118/5689/2237/9134/1019/5684/994/5000/5720/11065/902/8318/5682/246184/23594/1763/7027/5700/122706/7321/5707/207/9837/8697/5690/5717/1027/5982/9491/23198/6500/898/10274/5925/23244/4173/143471/5706/5705/10735/10197/4149/286826/23047/3978/8881/5885/5557/7316/10213/5709/5422/9978/4174/993/5695/890/4331/1026/84515/5714/5111/4171/4609/51433/9861/5715/4998/6119/5711/5928/2932/5701/5688/5687/5427/6502/5685/5683/5698/5708/10000/5692/5985/5686/5713/990/119504/8243/9126/595/5699/4175/5710/81620/5702/8900/51529/5984/7324/5719/64682/29945/10393/208/5704/6233/51434/5716/51343/23595/7311/25906/51659/113130/157570/5983/6117/29882/5001/5981/5694/7465/1163/5424/1022/5693/5721/5696/4999/5691/4176/7314/996 138 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-73894 DNA Repair 203/2027 334/10654 7.486587662631901e-66 8.191574667529738e-64 4.038817028525104e-64 10450/9318/11284/1017/7014/6118/2176/80010/54962/25/25913/3838/2237/6917/5434/5440/5893/2178/4436/83990/151987/902/7516/5888/4350/9156/5883/1763/328/27339/7486/5430/10111/83444/56852/5436/7320/10445/7520/51720/675/2956/5982/63967/404672/9557/7013/5531/9636/11200/545/472/6613/5441/7507/7706/80198/7336/86/5438/3978/3981/580/5431/11073/2072/5591/8450/5435/353497/54778/7316/9978/5433/116028/890/197342/85015/4331/64708/8314/641/79008/5111/1643/10635/2966/7415/7517/10980/64421/9656/283899/6119/84464/83932/3364/22976/29844/7341/10524/4798/4683/5437/79913/10401/5427/144715/1161/5889/9937/2177/1642/54617/2965/5985/10920/25898/2033/29089/84126/142/8914/7398/2068/5439/1111/10987/2071/7157/55215/8900/5984/1069/7329/9246/79728/64858/8924/57599/54891/6233/2067/2873/548593/2968/146956/672/5932/7158/7311/6047/2189/55120/7318/2187/2967/79184/56949/6612/3980/93973/60/8533/7156/8607/5890/5887/5983/9716/6117/2175/2073/5599/7334/5981/10038/7874/2547/55666/54386/5884/5810/5424/1022/5432/348654/8178/2188/83695/4437/5886/50813/57697/7508/7314/51514/22909/7374/51138/8451/8554/7528 203 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69239 Synthesis of DNA 108/2027 119/10654 1.6500952054728688e-65 1.6665961575275975e-63 8.217073290411452e-64 8454/5718/1017/4172/6118/5689/2237/9134/5684/5000/5720/11065/8318/5682/246184/23594/1763/5700/122706/7321/5707/9837/8697/5690/5717/5982/9491/23198/6500/898/4173/143471/5706/5705/10197/3978/8881/5557/7316/10213/5709/5422/9978/4174/5695/890/84515/5714/5111/4171/51433/9861/5715/4998/6119/5711/5701/5688/5687/5427/6502/5685/5683/5698/5708/5692/5985/5686/5713/990/119504/5699/4175/5710/81620/5702/8900/51529/5984/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/23595/7311/25906/51659/5983/6117/29882/5001/5981/5694/5424/5693/5721/5696/4999/5691/4176/7314/996 108 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69306 DNA Replication 112/2027 127/10654 9.049273186549827e-65 8.486925495671374e-63 4.184438353179056e-63 8454/5718/1017/4172/6118/5689/2237/9134/5684/5000/5720/11065/8318/5682/246184/23594/1763/5700/122706/7321/5707/8317/9837/8697/5690/5717/5982/9491/23198/6500/898/4173/143471/5706/5705/10197/3978/8881/5557/7316/10213/5709/5422/9978/4174/5695/890/84515/5714/5111/4171/51433/9861/51053/5715/4998/6119/5711/5701/5688/5687/10926/5427/6502/5685/5683/5698/5708/5692/5985/5686/5713/990/119504/5699/4175/5710/81620/5702/8900/51529/5984/7324/5719/64682/29945/10393/5704/6233/51434/55388/5716/51343/23595/7311/25906/51659/5983/6117/29882/5001/5981/5694/5424/5693/5721/5696/4999/5691/4176/7314/996 112 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69618 Mitotic Spindle Checkpoint 103/2027 112/10654 6.355550692242844e-64 5.563225372609903e-62 2.7429218777048065e-62 220134/5905/55839/11130/79682/5903/10403/11065/54908/6249/55143/246184/55055/25936/5525/9735/80776/1783/1058/7321/991/401541/79019/5526/348235/80152/8697/9212/1063/8379/3619/79172/147841/348995/23421/79023/55920/57122/79980/64105/6232/332/1780/8881/23122/5528/5048/1781/5501/57405/8655/4085/23279/55166/51433/79902/3796/54821/5519/9183/81565/2491/1062/699/22919/91687/1060/119504/79003/5529/51143/51529/7324/83540/64682/29945/10393/11004/5527/51434/701/7514/9184/5518/25906/54820/5347/57551/84643/29882/6396/23332/25909/64946/9793/10726/81930/55746/140735/996/5515/1778/5516 103 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69052 Switching of origins to a post-replicative state 89/2027 90/10654 1.0895244243165055e-63 8.940909807047323e-62 4.408273164175335e-62 8454/5718/1017/4172/5689/9134/5684/5000/5720/11065/5682/246184/23594/5700/122706/7321/5707/8697/5690/5717/9491/23198/6500/898/4173/143471/5706/5705/10197/8881/7316/10213/5709/9978/4174/5695/890/84515/5714/4171/51433/9861/5715/4998/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/990/119504/5699/4175/5710/81620/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/23595/7311/25906/29882/5001/5694/5693/5721/5696/4999/5691/4176/7314/996 89 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6807070 PTEN Regulation 118/2027 140/10654 1.778269087692849e-63 1.373451360082771e-61 6.771736773567196e-62 1912/5718/5689/3725/6591/5684/8841/5720/5682/5468/1822/23186/5700/122706/5707/2146/5978/9112/9219/8535/10273/207/51564/6045/5690/57690/5594/84232/5717/9491/23198/27327/80012/5931/1460/143471/5706/5705/10197/192670/7316/10213/5709/5695/1457/8658/1911/4734/5714/1108/57167/2122/9861/7101/81847/10014/5715/5711/1958/5928/5701/5688/84733/5687/57459/5685/5683/5698/5708/10000/5692/54815/5686/5713/23512/57332/5728/5699/5710/6615/5702/192669/3066/3065/7157/1107/23028/8975/5719/5987/5371/23112/208/5704/6233/2475/5716/57504/7311/1386/331/4343/8726/5694/23466/26523/80351/7874/53615/57521/5693/5721/5696/23608/5691/7314/6015/5595 118 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69206 G1/S Transition 112/2027 131/10654 1.2351217912289211e-61 9.009527288242074e-60 4.442104687753138e-60 8454/5718/1017/4172/6118/5689/26271/9134/1019/5684/5000/5720/902/8318/5682/23594/7027/5700/5707/8317/207/5690/5717/1027/9491/6500/898/5925/4173/5706/5705/10197/4149/286826/5557/7316/10213/5709/5422/4174/891/993/5695/890/1876/4331/983/1026/84515/5714/5111/4171/4609/9861/51053/5715/5519/4998/6119/5711/5928/5701/5688/5687/10926/5427/6502/5685/5683/5698/5708/10000/5692/5686/5713/990/595/5699/4175/5710/81620/5702/3065/8900/5719/208/5704/6233/7298/55388/5716/28227/23595/7311/5518/6117/1719/5001/5694/7465/1163/1022/5693/5721/5696/4999/5691/4176/7314/5515/6241/5516 112 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 85/2027 86/10654 9.154104340721325e-61 6.00966949968355e-59 2.9630390366019024e-59 8454/5718/1017/5689/8945/26271/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/9212/5717/9491/23198/6500/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/8556/7324/5719/64682/29945/10393/4751/9232/5704/6233/51434/5716/701/51343/7311/9184/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 85 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-453276 Regulation of mitotic cell cycle 85/2027 86/10654 9.154104340721325e-61 6.00966949968355e-59 2.9630390366019024e-59 8454/5718/1017/5689/8945/26271/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/9212/5717/9491/23198/6500/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/8556/7324/5719/64682/29945/10393/4751/9232/5704/6233/51434/5716/701/51343/7311/9184/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 85 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1257604 PIP3 activates AKT signaling 170/2027 264/10654 2.1337631933007315e-60 1.334110034668505e-58 6.577766234987218e-59 5295/1912/1147/5718/2308/5689/3725/6591/3643/5684/8841/5290/5720/3667/2309/5682/5291/5468/5525/1822/23186/842/5700/3815/122706/5707/2146/5978/8870/5526/9112/9219/8535/10273/207/51564/6045/5690/57690/5594/4303/84232/5717/1027/9491/23198/27327/80012/930/5931/1460/941/143471/5706/2064/5705/6199/10197/192670/2260/4615/5528/2100/7316/10213/5709/1950/5695/2263/1457/4233/8658/1026/1911/4734/5714/6714/2099/1108/57167/2122/9861/7101/81847/10014/5715/5519/5711/1958/5928/2932/2261/5701/5688/84733/5687/57459/5685/5683/5698/5708/10000/5692/54815/5686/5713/2534/23512/57332/5728/5699/5529/5710/6615/3630/5702/192669/3066/3065/7157/1107/23028/8975/942/5719/5987/3654/7189/5371/23112/208/5704/6233/5527/2885/2475/5716/7409/1385/57504/7311/3932/2931/5518/1386/1956/331/4343/8726/8394/5694/23466/26523/80351/7874/5781/53615/57521/5693/5721/5696/23608/5691/940/7314/6015/5595/4193/5515/5516 170 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-913531 Interferon Signaling 141/2027 199/10654 4.147393458460057e-58 2.4752398231627523e-56 1.220405252130591e-56 80263/3135/3665/3120/201626/5777/815/3837/3838/5903/6737/51447/10379/115362/960/23321/4281/7412/3117/3107/3119/10410/4502/2633/9021/85363/54739/9830/4600/3123/163351/23650/348995/9636/2209/79023/2537/3383/57122/11274/8638/55223/25820/7706/2634/51127/10762/3662/23087/3115/9470/23511/4684/7316/3122/3394/3663/8519/115361/3664/567/103/4734/3434/6672/3113/6772/10475/8651/23279/3433/3659/3106/79902/6041/3840/25939/1958/4939/388646/7341/6059/55128/10437/2635/1981/5771/1973/10612/3458/816/11074/3661/3669/10346/7324/3836/9246/1977/5371/51191/4599/6233/684/7311/81603/10107/3133/7318/3429/5610/10581/3134/117854/5300/9775/3452/3127/4940/91543/6396/3437/80128/7334/7726/79097/3456/6773/4938/5781/4261/3430/55746/3105/5696/3660/5495/5724/7314/5595/8554 141 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-453279 Mitotic G1-G1/S phases 118/2027 149/10654 1.152442249923115e-57 6.578942061517609e-56 3.243716172552475e-56 8454/5718/1017/4172/6118/5689/25/26271/9134/1019/5684/5000/5720/902/8318/5682/23594/1029/7027/5700/5707/8317/207/5690/5717/1027/9491/6500/7153/898/5925/4173/5706/5705/10197/4149/286826/5557/7316/10213/5709/5422/4174/891/993/5695/890/1876/4331/983/1026/84515/5714/5111/6714/4171/4609/9861/51053/5715/5519/4998/6119/5711/5928/5701/5688/5687/10926/5427/4067/6502/5685/5683/5698/5708/10000/5692/5686/5713/990/595/5699/4175/5710/81620/5702/3065/5520/8900/5719/208/5704/6233/7298/55388/5716/28227/23595/7311/5518/6117/1719/5001/5694/7465/1163/1022/5693/5721/5696/4999/5691/4176/7314/5515/6241/5516 118 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9006925 Intracellular signaling by second messengers 182/2027 305/10654 3.2516494209026866e-57 1.7731441880986688e-55 8.742403300442389e-56 5295/1912/1147/5718/2308/5689/3725/6591/815/3643/3838/5684/8841/5290/5720/3667/2309/5682/5291/5468/5525/1822/5575/23186/842/5700/3815/122706/5707/5567/2146/5978/8870/5526/9112/9219/8535/10273/207/51564/6045/5690/57690/5594/4303/5568/84232/5717/1027/9491/23198/27327/80012/930/5931/1460/941/143471/5706/2064/5705/6199/10197/192670/2260/4615/5573/5528/2100/7316/10213/5709/1950/5695/2263/1457/4233/8658/1026/1911/4734/10768/5714/6714/2099/1108/57167/2122/9861/7101/5566/81847/10014/5715/5519/5711/1958/5928/2932/2261/5701/5688/84733/5687/57459/5576/5685/5683/5698/5708/10000/5692/54815/5686/5713/2534/23512/57332/5728/5699/5529/5710/6615/816/3630/5702/192669/3066/3065/7157/1107/23028/8975/942/5719/5987/3654/7189/5371/23112/208/5577/5704/6233/5527/2885/2475/5716/7409/1385/57504/7311/3932/2931/5518/1386/1956/5581/331/4343/8726/8394/5694/23466/26523/80351/7874/5781/53615/57521/5693/5721/5696/23608/5691/940/7314/6015/5595/4193/5515/5516 182 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2262752 Cellular responses to stress 242/2027 479/10654 3.376131355861898e-57 1.7731441880986688e-55 8.742403300442389e-56 1912/5718/1017/3303/7014/6118/5689/3725/6782/815/25913/9134/1019/5684/5903/5601/5720/11065/573/4790/653361/5606/5682/64344/3159/246184/112399/7531/7290/1029/7027/1915/1783/5700/23334/122706/116835/7321/5707/2146/10111/8535/84962/6045/7422/8697/5690/10382/57690/5594/9530/3308/5717/1027/9491/23198/27327/80012/898/10049/5931/10294/5925/3091/7013/348995/1051/10013/143471/545/79023/5706/472/57122/5705/10197/3337/192670/3576/3313/10808/1780/10762/3490/8550/8881/7001/29855/23511/7323/1781/7316/10213/5709/9978/2114/5695/890/3305/8655/6774/5970/1026/1639/9261/1911/9532/54205/6667/5714/2289/23279/7415/8994/51433/9861/79902/4194/7322/91582/5715/6119/5711/26353/5598/3552/5928/1432/2932/5701/10524/5688/1387/84733/4683/5687/57805/7846/259217/3310/529/2908/5685/5683/3309/5698/5708/3320/5602/5692/5686/5713/2033/23512/119504/7266/57332/5699/5710/25842/126374/51143/3301/816/7428/5702/192669/9531/7157/8453/8900/51529/6648/23135/7324/10963/5719/64682/29945/10393/22824/23112/5609/5704/6233/2056/51434/3326/2475/5716/3306/27000/2353/51343/7311/6196/367/25906/2034/23411/84790/4343/8726/55662/6117/29882/5599/6396/5600/54583/5694/3304/3312/23466/4217/26523/3456/5052/2113/405/6416/5608/54386/3569/3297/57521/55746/5693/5721/55466/140735/5696/5691/10728/7314/996/6015/51182/5595/4193/2950/1778 242 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 79/2027 80/10654 2.1924486496408463e-56 1.1071865680686274e-54 5.4589308482960346e-55 8454/5718/1017/5689/8945/26271/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/6500/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/701/51343/7311/9184/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 79 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-68886 M Phase 212/2027 395/10654 9.649526761058267e-56 4.692529124914631e-54 2.3136292234116314e-54 10844/4000/5718/220134/5689/5905/55839/11130/22995/26271/79682/5684/5903/10403/5720/11065/54908/6249/55143/5682/64151/246184/55055/25936/5525/9735/7531/10142/80776/55869/1783/1058/5700/11190/122706/7321/5707/991/91754/401541/79019/5526/54801/5862/1454/348235/80152/8697/5690/10382/9212/5594/1063/8379/5717/3619/9491/23198/79172/10274/5925/1460/147841/23244/348995/23421/143471/79023/55920/5706/9133/57122/5705/79980/64105/10735/10197/6232/332/7443/23047/1780/10762/8881/23122/5885/23511/5528/5048/1781/7316/255919/10213/5709/891/5695/5501/57405/8655/4085/9738/1457/983/1639/5714/23279/55166/51433/9861/79902/5566/3796/5715/79959/54821/5519/84131/5711/9183/81565/5701/2491/5688/10112/1062/699/5687/7846/5685/7283/5683/5698/5708/3320/5692/22919/5686/5713/91687/1060/119504/79003/8243/9126/10426/5699/5529/5710/11064/51143/9918/5702/5520/10733/51529/1069/7324/83540/5719/64682/29945/10393/23399/79648/4751/11004/9232/5577/5704/6233/5527/9700/51434/5716/701/7514/7311/9184/5518/25906/55844/54820/5347/113130/57551/84790/84643/9493/29882/6396/5694/23332/22897/25909/64946/9793/10726/81930/55746/8481/5693/5721/140735/5696/10592/5691/7314/996/5595/5515/1778/5516 212 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8953897 Cellular responses to external stimuli 243/2027 493/10654 7.711582903252372e-55 3.6161815542751305e-53 1.7829411599624846e-53 1912/5718/1017/3303/7014/6118/5689/3725/6782/815/25913/9134/1019/5684/5903/5601/5720/11065/573/4790/653361/5606/5682/64344/3159/246184/112399/7531/7290/1029/7027/1915/1783/5700/23334/122706/116835/7321/5707/2146/10111/8535/84962/4502/6045/7422/8697/5690/10382/57690/5594/9530/3308/5717/1027/9491/23198/27327/80012/898/10049/5931/10294/5925/3091/7013/348995/1051/10013/143471/545/79023/5706/472/57122/5705/10197/3337/192670/3576/3313/10808/1780/10762/3490/8550/8881/7001/29855/23511/7323/1781/7316/10213/5709/9978/2114/5695/890/3305/8655/6774/5970/1026/1639/9261/1911/9532/54205/6667/5714/2289/23279/7415/8994/51433/9861/79902/4194/7322/91582/5715/6119/5711/26353/5598/3552/5928/1432/2932/5701/10524/5688/1387/84733/4683/5687/57805/7846/259217/3310/529/2908/5685/5683/3309/5698/5708/3320/5602/5692/5686/5713/2033/23512/119504/7266/57332/5699/5710/25842/126374/51143/3301/816/7428/5702/192669/9531/7157/8453/8900/51529/6648/23135/7324/10963/5719/64682/29945/10393/22824/23112/5609/5704/6233/2056/51434/3326/2475/5716/3306/27000/2353/51343/7311/6196/367/25906/2034/23411/84790/4343/8726/55662/6117/29882/5599/6396/5600/54583/5694/3304/3312/23466/4217/26523/3456/5052/2113/405/6416/5608/54386/3569/3297/57521/55746/5693/5721/55466/140735/5696/5691/10728/7314/996/6015/51182/5595/4193/2950/1778 243 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5696398 Nucleotide Excision Repair 96/2027 111/10654 6.95535875295427e-54 3.1490986353892953e-52 1.5526481426740023e-52 10450/9318/6118/6917/5434/5440/902/27339/5430/83444/5436/10445/5982/404672/9557/6613/5441/7507/7336/86/5438/3978/5431/2072/8450/5435/54778/7316/9978/5433/85015/4331/64708/5111/1643/2966/10980/283899/6119/29844/7341/4798/5437/79913/10401/5427/1161/1642/54617/2965/5985/10920/2033/142/2068/5439/10987/2071/5984/1069/7329/54891/6233/2067/2873/2968/7311/2967/56949/6612/3980/93973/60/8533/8607/5887/5983/9716/6117/2073/7334/5981/10038/7874/5424/1022/5432/8178/5886/50813/7508/7314/51138/8451/8554/7528 96 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 75/2027 76/10654 1.8009612119930327e-53 7.882206904489507e-52 3.886284720616545e-52 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/4751/9232/5704/6233/51434/5716/701/7311/9184/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 75 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5663202 Diseases of signal transduction 202/2027 377/10654 6.460597759966251e-53 2.736375760914738e-51 1.3491570873953294e-51 5295/8454/4000/1147/5718/2308/5689/2963/815/8805/5434/5440/5684/4893/11052/6464/8841/5290/5720/3667/79885/142678/2309/5682/5291/1499/5604/10018/5525/9734/10142/55869/842/5700/139285/3815/122706/5707/10956/5430/5526/8844/207/51564/5436/1452/5690/5594/3280/9530/4303/4041/5717/1027/9491/23198/6500/409/930/941/10533/10013/143471/5706/2064/5705/5441/6199/10197/2260/5438/5431/6776/5528/2100/5435/84447/4686/7316/10213/5709/673/9978/5433/1950/9611/5695/6774/2263/89780/4233/9759/8658/9612/1026/5714/6772/6714/2099/6934/50846/4609/5664/7415/9861/4089/10014/5715/2962/22938/5519/3549/8850/5711/2932/2261/5701/5688/1387/5437/5687/7046/4088/5685/5683/5698/5708/10000/3320/5692/5686/5713/324/2335/2534/2033/408/55294/5728/5699/8312/5529/1445/5710/11064/5439/816/5702/3066/3065/5894/4087/942/5719/208/5704/6233/5527/2885/2475/5716/7409/4040/1385/7048/7311/3932/2931/5518/1956/6469/11160/7855/60/4140/7040/9444/3845/6777/5694/3265/80351/369/4763/5781/4851/5432/22916/5693/5663/5721/5696/11140/5691/5245/7529/940/7314/5595/4193/5515/5516 202 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-141424 Amplification of signal from the kinetochores 87/2027 96/10654 9.3781322368167e-53 3.71790313590816e-51 1.8330945032136277e-51 220134/5905/55839/11130/79682/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/401541/79019/5526/348235/80152/9212/1063/8379/3619/79172/147841/348995/23421/79023/55920/57122/79980/64105/6232/332/1780/23122/5528/5048/1781/5501/57405/8655/4085/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/22919/91687/1060/79003/5529/51143/83540/11004/5527/701/7514/9184/5518/54820/5347/57551/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/5515/1778/5516 87 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 87/2027 96/10654 9.3781322368167e-53 3.71790313590816e-51 1.8330945032136277e-51 220134/5905/55839/11130/79682/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/401541/79019/5526/348235/80152/9212/1063/8379/3619/79172/147841/348995/23421/79023/55920/57122/79980/64105/6232/332/1780/23122/5528/5048/1781/5501/57405/8655/4085/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/22919/91687/1060/79003/5529/51143/83540/11004/5527/701/7514/9184/5518/54820/5347/57551/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/5515/1778/5516 87 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 74/2027 75/10654 9.627471943707346e-53 3.71790313590816e-51 1.8330945032136277e-51 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/4751/9232/5704/6233/51434/5716/701/7311/9184/25906/29882/5694/5693/5721/5696/5691/7314/996 74 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69481 G2/M Checkpoints 122/2027 168/10654 2.9998964675809385e-52 1.1253897319810777e-50 5.548680684397827e-51 5718/1017/4172/6118/5689/80010/5684/5000/5720/83990/8318/5682/9156/23594/5883/1763/7531/51512/5700/7486/122706/5707/10111/8317/5690/51720/5717/5982/9491/23198/63967/7533/2810/4173/11200/143471/545/5706/9133/472/5705/10197/7336/7534/580/11073/7316/10213/5709/4174/891/993/5695/116028/983/84515/641/5714/4171/9861/5715/9656/4998/6119/5711/3364/7341/5701/10524/5688/4683/5687/10926/144715/5685/5683/5698/5708/5692/5985/5686/5713/990/995/84126/5699/4175/5710/1111/5702/7157/5984/5719/8924/5704/6233/55388/5716/672/5932/7158/23595/7311/79184/7156/5983/6117/7334/5001/5694/7465/5884/5810/5693/5721/5696/4999/83695/5691/4176/7529/7314 122 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2500257 Resolution of Sister Chromatid Cohesion 102/2027 126/10654 1.2637744037793882e-51 4.609266089339824e-50 2.272576778726093e-50 220134/5905/55839/11130/79682/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/55869/1783/1058/991/401541/79019/5526/348235/80152/10382/9212/1063/8379/3619/79172/10274/147841/23244/348995/23421/79023/55920/9133/57122/79980/64105/10735/6232/332/23047/1780/23122/5885/5528/5048/1781/891/5501/57405/8655/4085/983/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/7846/22919/91687/1060/79003/8243/9126/5529/51143/83540/11004/5527/701/7514/9184/5518/54820/5347/113130/57551/84790/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/5515/1778/5516 102 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72/2027 73/10654 2.746326069763794e-51 9.745746296215841e-50 4.805093976969369e-50 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/890/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/4751/5704/6233/51434/5716/701/7311/9184/25906/29882/5694/5693/5721/5696/5691/7314/996 72 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 71/2027 72/10654 1.4654803716032425e-50 4.810439319787644e-49 2.3717642856210375e-49 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/9212/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/9232/5704/6233/51434/5716/51343/7311/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 71 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 71/2027 72/10654 1.4654803716032425e-50 4.810439319787644e-49 2.3717642856210375e-49 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/890/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/701/7311/9184/25906/29882/5694/5693/5721/5696/5691/7314/996 71 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 71/2027 72/10654 1.4654803716032425e-50 4.810439319787644e-49 2.3717642856210375e-49 5718/1017/5689/9134/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/5717/9491/23198/898/143471/5706/5705/10197/8881/7316/10213/5709/5695/890/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/990/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 71 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-68949 Orc1 removal from chromatin 70/2027 71/10654 7.815265503430557e-50 2.502791123415688e-48 1.2339892900153512e-48 8454/5718/1017/4172/5689/5684/5000/5720/5682/23594/5700/122706/5707/5690/5717/9491/23198/6500/4173/143471/5706/5705/10197/7316/10213/5709/9978/4174/5695/890/84515/5714/4171/9861/5715/4998/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/990/5699/4175/5710/81620/5702/8900/5719/5704/6233/5716/23595/7311/5001/5694/5693/5721/5696/4999/5691/4176/7314 70 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 103/2027 134/10654 3.514618656595802e-48 1.0987367371691162e-46 5.417269357910823e-47 5295/8454/1147/5718/5689/3725/8945/9402/5684/5601/4893/6464/4773/5290/5720/2205/4790/5682/5291/4772/5700/122706/7321/5707/5690/5532/5594/4775/5717/4214/9491/23198/6500/143471/5706/5705/2206/10197/8517/5530/7316/10213/5709/5695/7335/5970/4792/6850/10768/5714/9861/7322/5715/5711/5701/5688/5687/4067/23291/5588/5685/5683/5698/5708/5602/5692/5686/5713/2534/5534/5699/5710/5702/695/5719/7189/5609/5704/6233/2885/7410/7006/5716/7409/3702/2353/7311/3845/5599/7334/5694/3265/3551/6416/5062/5693/5721/5696/997/2207/5691/7314/5595 103 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-449147 Signaling by Interleukins 221/2027 461/10654 3.5271111789711927e-47 1.0769992972067851e-45 5.310093941413179e-46 5295/8454/6804/6095/3605/7124/1147/5718/2308/5689/3725/5777/8945/5897/596/5684/5601/351/6464/5290/5720/1437/3667/4790/6627/6597/5606/2309/5682/5291/5604/26469/5783/7412/5700/6351/122706/7184/5707/8767/356/6775/207/5292/5451/3684/9021/7422/29110/5690/3553/2625/5594/8878/4582/5717/2919/9491/23198/6500/5743/3091/941/143471/10538/4318/5706/3726/4312/3383/5705/6097/10197/4478/8517/6657/6778/3576/4615/7534/3313/332/3662/6776/5528/7316/3565/10213/5709/9978/2920/3560/5695/79155/6352/3185/6774/4314/7335/5970/4792/4205/3055/6850/1026/9261/4793/7133/5714/3606/6772/8651/8809/4609/3146/9861/5566/5715/5519/64127/5711/7132/5598/1901/3552/1432/4208/5701/5688/79923/5687/3558/4067/23291/4088/598/836/5685/5683/5698/5708/3320/5602/5692/5686/5713/4843/2335/2534/595/5699/57162/5771/5710/3458/3181/5702/2002/998/7157/6648/942/5719/3654/7189/5609/5704/6233/2885/7525/1398/7006/5716/7409/1385/2353/604/7311/6196/2939/6809/6347/3932/3575/5518/1386/5896/7040/6935/3687/5599/5600/7431/6777/7334/3600/5694/3312/3559/3574/3551/6773/6416/5781/5608/3569/3162/5062/5693/1234/5721/5696/3586/5691/4791/5724/7314/5595/5515/3598/5516 221 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 66/2027 67/10654 6.282181252198654e-47 1.874659996394735e-45 9.242922177277924e-46 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/9232/5704/6233/51434/5716/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 66 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-3700989 Transcriptional Regulation by TP53 189/2027 365/10654 1.5367395777114996e-46 4.48386459007822e-45 2.2107481644270697e-45 9377/1017/6118/2176/80010/5563/3725/2963/6917/9134/5434/5440/4436/83990/902/1329/9156/5883/1763/7531/1029/7027/79370/7486/5430/10111/9219/6874/8445/207/5436/22974/9212/57690/204851/7832/1027/5982/404672/27327/898/5931/355/7533/2810/55367/1460/6749/11200/545/472/5441/192670/7534/332/5438/580/5431/8550/7469/11073/7001/5435/7316/5433/891/6872/84987/116028/890/80196/1457/54971/4331/983/1026/54205/6790/641/6341/5111/1108/1643/8148/2966/8797/4194/9150/2962/9656/5519/6119/147923/5928/3364/1432/5571/10524/1387/4683/5437/8812/144715/57459/1616/843/2177/10000/2965/5985/54815/51755/2033/995/84126/5728/900/905/2068/5439/1111/192669/3066/3065/2071/7157/1107/55215/8900/5984/8626/6827/5371/23112/208/10498/6233/5527/2968/2475/672/5932/1025/2353/604/7311/7161/2967/5562/5518/1386/6908/4513/8851/5300/7156/5983/4343/6117/11198/1327/5600/904/7936/6829/26523/51497/7874/5052/637/1020/5608/5884/5810/53615/1022/8795/5432/57521/26013/8178/83695/7529/7314/4193/5515/25920/1263/5516 189 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-68877 Mitotic Prometaphase 129/2027 200/10654 5.462372081313044e-46 1.5591509875573972e-44 7.687319977133919e-45 10844/220134/5905/55839/11130/22995/79682/5903/10403/54908/6249/55143/64151/55055/25936/5525/9735/7531/10142/80776/55869/1783/1058/11190/991/401541/79019/5526/54801/1454/348235/80152/10382/9212/1063/8379/3619/79172/10274/1460/147841/23244/348995/23421/79023/55920/9133/57122/79980/64105/10735/6232/332/23047/1780/23122/5885/5528/5048/1781/891/5501/57405/8655/4085/9738/1457/983/1639/23279/55166/79902/5566/3796/79959/54821/5519/84131/9183/81565/2491/1062/699/7846/7283/3320/22919/91687/1060/79003/8243/9126/10426/5529/11064/51143/9918/10733/1069/83540/4751/11004/5577/5527/701/7514/9184/5518/54820/5347/113130/57551/84790/84643/6396/23332/22897/25909/64946/9793/10726/81930/55746/8481/140735/10592/5515/1778/5516 129 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-202424 Downstream TCR signaling 83/2027 98/10654 3.466828011969779e-45 9.684989744077276e-44 4.775138247170021e-44 5295/8454/1147/5718/3120/5689/8945/5684/5290/5720/4790/5682/5291/5700/3117/122706/7321/5707/3119/8767/5690/5717/9491/23198/6500/3123/143471/5706/5705/10197/8517/919/3115/7316/10213/5709/3122/5695/7335/5970/4792/5714/3113/9861/7322/5715/5711/5701/5688/5687/23291/915/5588/5685/917/5683/5698/5708/5692/5686/5713/5728/5699/5710/916/5702/5719/7189/5704/6233/5716/7311/3932/3127/7334/5694/3551/5693/5721/5696/997/5691/7314 83 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 75/2027 84/10654 1.7464738250716914e-44 4.7773336089981895e-43 2.355441671971689e-43 9318/6118/902/83444/10445/5982/404672/9557/6613/7507/7336/86/3978/2072/8450/54778/7316/9978/85015/4331/64708/5111/1643/2966/10980/283899/6119/29844/7341/4798/79913/10401/5427/1642/54617/2965/5985/10920/142/2068/10987/2071/5984/1069/7329/54891/6233/2067/2873/2968/7311/2967/6612/3980/93973/60/8533/8607/5887/5983/6117/2073/7334/5981/10038/5424/1022/5886/50813/7508/7314/51138/8451/8554/7528 75 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 62/2027 63/10654 4.998631095593568e-44 1.3394291078600725e-42 6.603991673018356e-43 5718/5689/5684/5720/11065/5682/246184/5700/7321/5707/8697/5690/5717/9491/5706/5705/10197/8881/7316/10213/5709/5695/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 62 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-877300 Interferon gamma signaling 79/2027 92/10654 5.494067600545307e-44 1.4427421519031976e-42 7.113371735442872e-43 80263/3135/3665/3120/5777/815/6737/10379/115362/960/23321/4281/7412/3117/3107/3119/4502/2633/9021/85363/9830/3123/163351/23650/2209/3383/8638/55223/7706/2634/51127/3662/23087/3115/4684/3122/3394/3663/115361/3664/567/6672/3113/6772/10475/8651/3659/3106/4939/388646/7341/55128/10437/2635/5771/10612/3458/816/11074/3661/10346/5371/81603/10107/3133/3134/117854/3127/4940/80128/7726/79097/4938/5781/4261/3105/3660/5724/8554 79 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69275 G2/M Transition 125/2027 196/10654 8.559213743012856e-44 2.2035779695246824e-42 1.0864636639737682e-42 10844/8454/5718/1017/5689/22822/8945/22995/5684/994/5720/902/2305/5682/7531/51512/10142/4659/5700/11190/122706/5707/54801/84962/1454/22974/5690/10382/3161/1063/5717/9491/23198/6500/51400/143471/5706/9133/5705/10197/286826/5048/1781/7316/10213/5709/9978/891/993/5695/890/8655/9738/4331/983/1026/1639/6790/5714/9861/5566/5715/79959/5519/84131/5711/5928/5701/5688/5687/23291/7846/5685/7283/5683/5698/5708/3320/5692/22919/5686/5713/2033/995/10426/5699/5710/11064/5702/5520/7157/10733/8900/1069/5719/4751/5577/5704/6233/3326/5716/28227/7514/7311/23194/5518/54820/5347/84790/5694/23332/22897/7465/9793/1022/8481/5693/5721/5696/5691/5500/7314/5515/1778/5516 125 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69002 DNA Replication Pre-Initiation 75/2027 85/10654 1.214061337082879e-43 3.0655048761342697e-42 1.5114326362469042e-42 5718/1017/4172/6118/5689/5684/5000/5720/8318/5682/23594/5700/122706/5707/8317/5690/5717/9491/23198/4173/143471/5706/5705/10197/5557/7316/10213/5709/5422/4174/5695/84515/5714/4171/9861/51053/5715/4998/6119/5711/5701/5688/5687/10926/5427/5685/5683/5698/5708/5692/5686/5713/990/5699/4175/5710/81620/5702/5719/5704/6233/55388/5716/23595/7311/6117/5001/5694/5693/5721/5696/4999/5691/4176/7314 75 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5687128 MAPK6/MAPK4 signaling 77/2027 89/10654 2.098968148876197e-43 5.199896565046126e-42 2.563784332788205e-42 5718/2308/5689/2118/3725/5897/5684/5720/2309/5682/5700/122706/5707/5567/5690/57690/5568/5717/9491/3315/23198/27327/143471/5706/5705/10197/3337/192670/5596/8550/7316/10213/5709/5695/983/5597/5714/4609/9861/5566/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/192669/998/8556/5719/23112/5704/6233/5716/7514/7311/8997/5896/4343/5694/26523/8202/5062/5693/5721/5696/5691/7314 77 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-453274 Mitotic G2-G2/M phases 125/2027 198/10654 4.2687988215224885e-43 1.0379505282701902e-41 5.117565838667311e-42 10844/8454/5718/1017/5689/22822/8945/22995/5684/994/5720/902/2305/5682/7531/51512/10142/4659/5700/11190/122706/5707/54801/84962/1454/22974/5690/10382/3161/1063/5717/9491/23198/6500/51400/143471/5706/9133/5705/10197/286826/5048/1781/7316/10213/5709/9978/891/993/5695/890/8655/9738/4331/983/1026/1639/6790/5714/9861/5566/5715/79959/5519/84131/5711/5928/5701/5688/5687/23291/7846/5685/7283/5683/5698/5708/3320/5692/22919/5686/5713/2033/995/10426/5699/5710/11064/5702/5520/7157/10733/8900/1069/5719/4751/5577/5704/6233/3326/5716/28227/7514/7311/23194/5518/54820/5347/84790/5694/23332/22897/7465/9793/1022/8481/5693/5721/5696/5691/5500/7314/5515/1778/5516 125 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8878166 Transcriptional regulation by RUNX2 92/2027 121/10654 2.0217569370749514e-42 4.826485197053474e-41 2.3796756292843924e-41 8454/57154/5718/8493/5689/25/1019/5684/8841/5720/5682/5700/122706/5707/10273/207/5690/5594/3280/5717/9491/23198/6500/5925/59269/10013/143471/5706/5705/10197/2737/7316/10213/5709/9978/891/865/5695/4094/11059/9759/983/1026/10413/5714/6772/6714/2099/9464/9861/4089/5715/2736/3549/5711/2932/5701/5688/5687/6502/2908/5685/5683/5698/5708/10000/5692/5686/5713/595/55294/5699/5710/5702/23314/861/5719/208/5704/6233/7525/5716/7311/367/860/5694/5693/5721/5696/5691/7314/5595 92 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-202403 TCR signaling 91/2027 119/10654 2.4720228875248354e-42 5.796010805928766e-41 2.857695631255214e-41 5295/8454/1147/5718/3120/5689/8945/9402/5684/5290/5720/4790/5682/5291/4690/5700/3117/122706/7321/5707/3119/8767/5690/5717/9491/23198/6500/3123/143471/5706/5705/5788/10197/8517/919/3115/7316/10213/5709/3122/5695/7335/5970/4792/5714/3113/9861/7322/5715/5711/5701/5688/5687/23291/915/5588/5685/917/5683/5698/5708/5692/5686/5713/5728/5699/1445/5710/916/5702/5719/7189/7535/5704/6233/5716/3702/26191/7311/3932/3127/7334/5694/3551/5062/5693/5721/5696/997/5691/7314 91 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 74/2027 85/10654 3.665201478674986e-42 8.442823757017994e-41 4.162694200157187e-41 8454/5718/1017/5689/9134/1019/5684/994/5720/902/5682/7027/5700/5707/207/5690/5717/1027/9491/6500/898/5925/5706/5705/10197/4149/286826/7316/10213/5709/993/5695/890/4331/1026/5714/4609/9861/5715/5711/5928/5701/5688/5687/6502/5685/5683/5698/5708/10000/5692/5686/5713/595/5699/5710/5702/8900/5719/208/5704/6233/5716/51343/7311/5694/7465/1163/1022/5693/5721/5696/5691/7314 74 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 59/2027 60/10654 7.436806113826646e-42 1.6007420372876044e-40 7.892382674725432e-41 8454/1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/9039/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/9020/5970/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5971/5694/5693/5721/5696/5691/4791/7314 59 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5610780 Degradation of GLI1 by the proteasome 59/2027 60/10654 7.436806113826646e-42 1.6007420372876044e-40 7.892382674725432e-41 8454/5718/5689/8945/5684/5720/2735/5682/5700/122706/5707/5567/51684/5690/5568/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/8650/5714/9861/5566/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/83737/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 59 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5610783 Degradation of GLI2 by the proteasome 59/2027 60/10654 7.436806113826646e-42 1.6007420372876044e-40 7.892382674725432e-41 8454/5718/5689/8945/5684/5720/5682/5700/122706/5707/5567/1452/51684/5690/5568/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5566/5715/2736/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 59 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 59/2027 60/10654 7.436806113826646e-42 1.6007420372876044e-40 7.892382674725432e-41 8454/5718/5689/8945/5684/5720/5682/5700/122706/5707/5567/1452/51684/5690/5568/5717/9491/23198/6500/143471/5706/5705/10197/2737/7316/10213/5709/9978/5695/5714/9861/5566/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 59 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-68867 Assembly of the pre-replicative complex 64/2027 68/10654 1.2144598741801815e-41 2.5719126045138357e-40 1.2680693083545188e-40 5718/4172/5689/5684/5000/5720/5682/23594/5700/122706/5707/5690/5717/9491/23198/4173/143471/5706/5705/10197/7316/10213/5709/4174/5695/84515/5714/4171/9861/51053/5715/4998/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/990/5699/4175/5710/81620/5702/5719/5704/6233/5716/23595/7311/5001/5694/5693/5721/5696/4999/5691/4176/7314 64 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1234174 Cellular response to hypoxia 68/2027 75/10654 1.9062516205197253e-41 3.9728704408609515e-40 1.958804923341071e-40 5718/5689/5684/5720/5682/64344/112399/5700/122706/7321/5707/84962/7422/5690/5717/9491/23198/3091/143471/5706/5705/10197/7323/7316/10213/5709/9978/5695/5714/8994/9861/7322/5715/5711/5701/5688/1387/5687/5685/5683/5698/5708/5692/5686/5713/2033/5699/5710/126374/7428/5702/8453/5719/5704/6233/2056/5716/7311/2034/55662/54583/5694/405/5693/5721/5696/5691/7314 68 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-162906 HIV Infection 136/2027 233/10654 2.992501808963226e-41 6.139304492451119e-40 3.0269549547901056e-40 60489/5718/5689/5905/8945/1173/2963/3837/2237/6917/5434/5440/164/5684/5903/8065/5720/902/5682/3159/5700/122706/5707/2959/5430/6874/5436/5690/7520/5717/9491/23198/6500/404672/6749/348995/143471/79023/5706/57122/5705/5441/10197/5438/3978/3981/10762/5431/7469/919/23511/5435/79720/4686/7316/10213/5709/9978/5433/5695/6872/2960/567/4331/3055/926/5714/23279/8148/2966/9861/79902/9150/5715/2962/5711/23327/5701/5688/5437/8812/5687/5685/5683/5698/5708/5692/2965/5686/5713/2534/5699/905/5710/2068/5439/5702/2071/5719/3836/6827/5704/6233/2968/5716/7514/1025/7311/2967/3932/6908/7251/11198/6396/904/5694/7936/6829/51497/2547/2961/1022/5062/5432/55746/22916/5693/1234/5721/5696/8178/5691/2957/940/7314/25920 136 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5676590 NIK-->noncanonical NF-kB signaling 58/2027 59/10654 3.9352397342085583e-41 7.828742077296724e-40 3.859924141209351e-40 8454/1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/9039/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/9020/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5971/5694/5693/5721/5696/5691/4791/7314 58 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 58/2027 59/10654 3.9352397342085583e-41 7.828742077296724e-40 3.859924141209351e-40 5718/5689/5684/5000/5720/5682/23594/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/84515/5714/9861/51053/5715/4998/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/990/5699/5710/81620/5702/5719/5704/6233/5716/23595/7311/5001/5694/5693/5721/5696/4999/5691/7314 58 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5663220 RHO GTPases Activate Formins 99/2027 140/10654 7.479642578431087e-41 1.465786672459704e-39 7.2269916508014436e-40 220134/5905/55839/11130/79682/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/1856/401541/79019/5526/348235/80152/10382/9212/1063/8379/3619/79172/147841/348995/23421/79023/55920/57122/79980/64105/6232/332/1780/23122/5528/5048/1781/5501/57405/8655/4085/6714/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/7846/22919/91687/1060/79003/23002/5529/51143/998/83540/11004/5527/1855/701/1857/7514/23380/9184/5518/54820/5347/387/57551/60/84790/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/5515/1778/5516 99 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69202 Cyclin E associated events during G1/S transition 72/2027 83/10654 8.118871967226585e-41 1.5676586607306624e-39 7.729266656105806e-40 8454/5718/1017/5689/9134/1019/5684/5720/902/5682/7027/5700/5707/207/5690/5717/1027/9491/6500/898/5925/5706/5705/10197/4149/286826/7316/10213/5709/993/5695/890/4331/1026/5714/4609/9861/5715/5711/5928/5701/5688/5687/6502/5685/5683/5698/5708/10000/5692/5686/5713/595/5699/5710/5702/8900/5719/208/5704/6233/5716/7311/5694/7465/1163/1022/5693/5721/5696/5691/7314 72 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 62/2027 66/10654 3.1232274823399386e-40 5.943185049728027e-39 2.9302591939573793e-39 5718/5689/5684/5720/5682/64344/112399/5700/122706/7321/5707/84962/5690/5717/9491/23198/3091/143471/5706/5705/10197/7323/7316/10213/5709/9978/5695/5714/8994/9861/7322/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/126374/7428/5702/8453/5719/5704/6233/5716/7311/2034/54583/5694/5693/5721/5696/5691/7314 62 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-195253 Degradation of beta-catenin by the destruction complex 71/2027 82/10654 3.808536939633115e-40 7.1437271453404e-39 3.522180778758445e-39 8454/5718/5689/8945/5684/5720/5682/1499/5525/5700/139285/122706/5707/5526/10023/1452/5690/5717/9491/23198/6500/143471/5706/5705/10197/5528/7316/10213/5709/9978/5695/23401/5714/6934/9861/5715/5519/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/324/5699/8312/5529/5710/5702/3065/5719/5704/6233/5527/5716/7311/5518/5694/5693/5721/5696/5691/7314/5515/5516 71 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69615 G1/S DNA Damage Checkpoints 63/2027 68/10654 6.8513126361912396e-40 1.2670103508900137e-38 6.246934427364882e-39 5718/1017/5689/9134/5684/5720/5682/1029/5700/122706/5707/5690/5717/1027/9491/23198/898/11200/143471/5706/472/5705/10197/7316/10213/5709/993/5695/890/1026/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/7157/8900/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314/4193 63 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 58/2027 60/10654 9.64904542961572e-40 1.759610645706311e-38 8.675676811715889e-39 8454/5718/1017/5689/9134/1019/5684/5720/5682/5700/5707/5690/5717/1027/9491/6500/898/5706/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/595/5699/5710/5702/8900/5719/5704/6233/5716/7311/5694/1163/5693/5721/5696/5691/7314 58 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5607764 CLEC7A (Dectin-1) signaling 80/2027 101/10654 2.3432930862784965e-39 4.214717564772145e-38 2.0780465004488472e-38 8454/1147/5718/5689/8945/5684/4773/5720/4790/5682/4772/5700/122706/7321/5707/5690/3553/5532/9039/4775/5717/9491/23198/6500/143471/5706/5705/841/10197/8517/5530/7316/10213/5709/5695/9020/7335/5970/4792/6850/10768/5714/6714/9861/7322/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5534/5699/5710/5702/9040/5719/7189/5704/6233/5716/7311/5971/7334/5694/3551/5693/5721/5696/997/5691/4791/7314 80 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 55/2027 56/10654 5.806154388968491e-39 1.0302000963129227e-37 5.079352701586944e-38 5718/3303/5689/5684/5720/5682/5700/122706/5707/5690/3184/5717/9491/3315/23198/26986/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/1981/5699/5710/5702/5719/5704/6233/5716/7311/5694/3304/3312/5693/5721/5696/5691/7314 55 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8948751 Regulation of PTEN stability and activity 63/2027 69/10654 6.440483215065362e-39 1.1275139281841093e-37 5.559153933003786e-38 5718/5689/5684/5720/5682/5700/122706/5707/10273/207/5690/5717/9491/23198/1460/143471/5706/5705/10197/7316/10213/5709/5695/1457/8658/4734/5714/9861/81847/5715/5711/5701/5688/5687/5685/5683/5698/5708/10000/5692/5686/5713/5728/5699/5710/5702/8975/5719/5987/208/5704/6233/5716/7311/331/5694/80351/5693/5721/5696/23608/5691/7314 63 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 80/2027 102/10654 8.886212523724886e-39 1.5352101373224705e-37 7.56928075081829e-38 8454/8792/7124/1147/5718/5689/8945/4050/5684/5720/7186/5682/5700/122706/5707/356/8600/5690/9039/5717/9491/23198/6500/330/143471/5706/5705/10197/10673/7316/10213/5709/5695/9020/7133/5714/9861/5715/5711/7132/5701/5688/329/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/4049/8740/5704/6233/5716/7311/5971/115650/7187/51330/958/5694/8771/5693/5721/8742/5696/5691/939/4791/959/7314/4055 80 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69563 p53-Dependent G1 DNA Damage Response 61/2027 66/10654 1.7053876434748078e-38 2.870735866515926e-37 1.4154027000499417e-37 5718/1017/5689/9134/5684/5720/5682/1029/5700/122706/5707/5690/5717/1027/9491/23198/898/11200/143471/5706/472/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/8900/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314/4193 61 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 61/2027 66/10654 1.7053876434748078e-38 2.870735866515926e-37 1.4154027000499417e-37 5718/1017/5689/9134/5684/5720/5682/1029/5700/122706/5707/5690/5717/1027/9491/23198/898/11200/143471/5706/472/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/8900/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314/4193 61 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 54/2027 55/10654 3.0636141023064346e-38 4.966080637442406e-37 2.448502498919373e-37 8454/5718/5689/8945/26271/5684/5720/5682/5700/122706/5707/991/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/51343/7311/5694/5693/5721/5696/5691/7314 54 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-4641257 Degradation of AXIN 54/2027 55/10654 3.0636141023064346e-38 4.966080637442406e-37 2.448502498919373e-37 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/64750/7316/10213/5709/5695/8658/5714/9861/81847/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/8312/5710/5702/8313/5719/5704/6233/5716/7311/5694/80351/5693/5721/5696/5691/7314 54 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8941858 Regulation of RUNX3 expression and activity 54/2027 55/10654 3.0636141023064346e-38 4.966080637442406e-37 2.448502498919373e-37 57154/5718/5689/5684/5720/5682/1029/864/5700/5707/5690/5717/9491/5706/5705/10197/64750/7316/10213/5709/865/5695/5714/6714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/2033/5699/5710/5702/5719/5704/6233/5716/7311/7040/5694/5693/5721/5696/5691/7314/4193 54 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 70/2027 83/10654 5.198632645071602e-38 8.324152028023187e-37 4.104183667161791e-37 8454/1147/5718/5689/8945/5684/4893/4773/5720/4790/5966/5682/4772/5700/122706/5707/5690/5532/4775/5717/9491/23198/6500/143471/5706/5705/10197/8517/5530/7316/10213/5709/5695/5970/4792/4793/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5534/5699/5710/5702/5719/5704/6233/5716/7311/4794/3845/5694/3265/3551/5693/5721/5696/5691/7314 70 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-4641258 Degradation of DVL 55/2027 57/10654 1.3523696978941961e-37 2.1393511004037102e-36 1.0547969108496267e-36 5718/5689/5684/5720/5682/5700/122706/5707/1856/5690/5717/9491/23198/143471/5706/5705/10197/8452/7316/10213/5709/9978/5695/5714/59349/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/1855/5716/1857/23072/7311/5694/5693/5721/5696/5691/7314 55 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1169091 Activation of NF-kappaB in B cells 61/2027 67/10654 1.5565553600206917e-37 2.4330442710799622e-36 1.1996009353542927e-36 8454/1147/5718/5689/8945/5684/5720/4790/5966/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/8517/7316/10213/5709/5695/5970/4792/4793/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/4794/5694/3551/5693/5721/5696/5691/7314 61 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 53/2027 54/10654 1.615318169011012e-37 2.466177623152859e-36 1.2159371774073101e-36 8454/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/6790/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/23194/5694/5693/5721/5696/5691/7314 53 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9604323 Negative regulation of NOTCH4 signaling 53/2027 54/10654 1.615318169011012e-37 2.466177623152859e-36 1.2159371774073101e-36 8454/5718/5689/5684/5720/5682/5700/5707/207/5690/5717/9491/6500/5706/5705/10197/10460/7534/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/4855/55294/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 53 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8878159 Transcriptional regulation by RUNX3 76/2027 96/10654 2.0722558856719046e-37 3.127439055042771e-36 1.541968989338441e-36 57154/5718/5689/5684/5720/2309/5682/1499/10018/1029/864/5700/5707/5690/3280/5717/9491/5706/5705/6097/10197/64750/6696/3683/7316/10213/5709/865/5695/9759/1026/10413/5714/6714/6934/4609/9861/4089/5715/22938/8850/5711/5701/5688/1387/5687/4088/5685/5683/5698/5708/5692/5686/5713/2033/595/5699/5710/5702/7157/861/5719/5704/6233/5716/7311/7040/3845/5694/4851/5693/5721/5696/5691/7314/4193 76 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2871837 FCERI mediated NF-kB activation 69/2027 82/10654 2.368810045165738e-37 3.5343722605711525e-36 1.7426054758097238e-36 8454/1147/5718/5689/8945/5684/5720/2205/4790/5682/5700/122706/7321/5707/5690/5717/9491/23198/6500/143471/5706/5705/2206/10197/8517/7316/10213/5709/5695/7335/5970/4792/5714/9861/7322/5715/5711/5701/5688/5687/4067/23291/5588/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/7189/5704/6233/5716/7311/7334/5694/3551/5693/5721/5696/997/2207/5691/7314 69 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5357801 Programmed Cell Death 111/2027 181/10654 1.275878261580112e-36 1.882278828600772e-35 9.280486468028019e-36 4000/5718/5533/5689/11035/3837/596/5684/5720/7186/1612/5682/1499/10018/7531/1029/7027/842/5700/122706/5707/8737/356/207/5690/5594/10059/5717/9491/23198/63967/355/330/7533/2810/143471/5706/5705/841/10197/7099/7534/7316/10213/5709/5695/8655/6774/54205/5714/8797/3146/9861/5715/5711/5701/5688/329/5687/999/5588/598/56616/836/5685/5683/929/5698/5708/10000/5692/5686/5713/324/8837/5534/5699/4137/5710/3002/5702/7157/8626/5719/3836/208/5704/6233/5716/7311/7161/840/8772/331/5599/8717/7431/5694/637/8743/8795/5062/5693/5721/6304/140735/5696/5691/7529/7314/5595 111 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 51/2027 52/10654 4.4804399232832686e-36 6.325610343302078e-35 3.11881217070652e-35 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69610 p53-Independent DNA Damage Response 51/2027 52/10654 4.4804399232832686e-36 6.325610343302078e-35 3.11881217070652e-35 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 51/2027 52/10654 4.4804399232832686e-36 6.325610343302078e-35 3.11881217070652e-35 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 51/2027 52/10654 4.4804399232832686e-36 6.325610343302078e-35 3.11881217070652e-35 5718/5689/1019/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/595/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9020702 Interleukin-1 signaling 78/2027 103/10654 6.737457323015601e-36 9.410937728850515e-35 4.640018201180957e-35 8454/1147/5718/5689/8945/5684/351/5720/4790/5682/5604/5700/122706/5707/8767/5690/3553/8878/5717/9491/23198/6500/143471/5706/5705/10197/8517/4615/7316/10213/5709/9978/5695/79155/7335/5970/4792/4793/5714/3146/9861/5715/64127/5711/3552/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/57162/5710/5702/5719/3654/7189/5704/6233/5716/7311/7334/5694/3551/6416/5608/5693/5721/5696/5691/4791/7314 78 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-109581 Apoptosis 109/2027 178/10654 6.83523995219445e-36 9.447021112875066e-35 4.657808942492617e-35 4000/5718/5533/5689/3837/596/5684/5720/7186/1612/5682/1499/10018/7531/1029/7027/842/5700/122706/5707/8737/356/207/5690/5594/10059/5717/9491/23198/63967/355/7533/2810/143471/5706/5705/841/10197/7099/7534/7316/10213/5709/5695/8655/6774/54205/5714/8797/3146/9861/5715/5711/5701/5688/329/5687/999/5588/598/56616/836/5685/5683/929/5698/5708/10000/5692/5686/5713/324/8837/5534/5699/4137/5710/3002/5702/7157/8626/5719/3836/208/5704/6233/5716/7311/7161/840/8772/331/5599/8717/7431/5694/637/8743/8795/5062/5693/5721/6304/140735/5696/5691/7529/7314/5595 109 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69541 Stabilization of p53 54/2027 57/10654 1.0885604366519904e-35 1.4888331805458994e-34 7.340621365580856e-35 5718/5689/5684/5720/5682/1029/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/472/5705/10197/7316/10213/5709/5695/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314/4193 54 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8939902 Regulation of RUNX2 expression and activity 63/2027 73/10654 1.4902264564793744e-35 2.017182822017957e-34 9.945624207648564e-35 8454/57154/5718/5689/5684/5720/5682/5700/122706/5707/10273/5690/5717/9491/23198/6500/59269/143471/5706/5705/10197/7316/10213/5709/9978/865/5695/11059/5714/6772/2099/9861/5715/5711/2932/5701/5688/5687/6502/2908/5685/5683/5698/5708/5692/5686/5713/55294/5699/5710/5702/5719/5704/6233/5716/7311/860/5694/5693/5721/5696/5691/7314 63 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5632684 Hedgehog 'on' state 69/2027 85/10654 2.2830058416809655e-35 3.0587619082929672e-34 1.5081080479417765e-34 57154/5718/5689/5684/5720/2735/339745/5682/6608/5700/122706/5707/22873/1452/51684/5690/5717/9491/23198/409/79577/143471/5706/5705/10197/64750/8452/2737/7316/10213/5709/9978/5695/8650/5714/50846/9861/5715/2736/8405/3549/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/408/5699/5710/5702/83737/5719/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 69 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5621481 C-type lectin receptors (CLRs) 94/2027 142/10654 4.1027655630672126e-35 5.441344630613384e-34 2.682829156072659e-34 8454/1147/5718/5689/8945/5684/4893/4773/5720/4790/5682/4772/5700/122706/7321/5707/5567/5690/3553/5532/9039/5568/4775/4582/5717/9491/23198/6500/143471/5706/5705/841/10197/8517/5530/7316/10213/5709/5695/9020/7335/5970/4792/6850/10768/5714/6714/9861/5566/7322/5715/5711/5701/5688/1387/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/2534/2033/5534/5699/5710/5702/9040/5894/5719/7189/5704/6233/5716/7311/5971/3845/7334/5694/3265/3551/5062/5693/5721/5696/997/2207/5691/4791/7314 94 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-983705 Signaling by the B Cell Receptor (BCR) 81/2027 112/10654 9.301871380392807e-35 1.2213357122455756e-33 6.021737788359554e-34 5295/8454/1147/5718/5689/5777/8945/5684/4893/4773/5720/4790/5966/5682/4690/4772/5700/122706/5707/5690/5532/4775/5717/9491/23198/6500/930/143471/5706/5705/10197/8517/5530/7316/10213/5709/5695/5970/4792/6850/10768/4793/5714/9861/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/2534/5534/5699/5710/5702/695/5719/5704/6233/2885/5716/7409/7311/4794/3845/5694/3265/3551/5693/5721/5696/5691/7314 81 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5688426 Deubiquitination 149/2027 297/10654 1.1743483613371256e-34 1.5266528697382633e-33 7.527089548956042e-34 9960/5718/5689/5684/5720/3607/10617/7186/6314/5682/5700/122706/7321/5707/991/51377/8737/83444/8767/8237/4738/5690/2625/9817/57506/4303/10445/51720/5717/9491/23198/63967/409/6478/1080/330/3091/9101/143471/5706/5705/11274/4287/55031/10197/7706/8517/86/64750/580/7316/10213/5709/993/5695/79155/890/4792/9738/8658/983/8314/11047/5714/8678/2099/1643/4609/7415/9861/4194/4089/81847/5715/283899/64127/8850/5711/29844/5701/4798/5688/9097/329/79913/5687/7046/6502/4088/8078/5685/114803/5683/5698/5708/54617/5692/5686/5713/324/2033/408/5728/5699/8312/5710/5702/7157/8900/9958/8313/8975/4087/10868/63891/5719/7189/57599/54891/5704/6233/5716/672/7048/7311/367/79184/7187/93973/387/60/23770/7040/8607/5887/3054/1540/29761/5694/80351/7874/5693/5721/5696/5691/5886/7314/4193/7528 149 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 49/2027 50/10654 1.2388850835920418e-34 1.594760896819952e-33 7.862892945398407e-34 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5062/5693/5721/5696/5691/7314 49 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5663205 Infectious disease 176/2027 383/10654 1.6523389788888939e-34 2.106331144933124e-33 1.0385165784534182e-33 60489/6804/5718/3303/5689/5905/6138/8945/1173/2963/3837/3838/2237/6917/5434/5440/164/5684/5903/8065/6857/5720/902/6128/5606/5682/1499/5604/1938/3159/6129/5700/122706/5707/2959/5430/6874/5436/6152/5690/2060/7520/8106/5717/9491/23198/6500/404672/6749/348995/6141/9636/143471/6202/79023/5706/57122/5705/5441/10197/6232/5438/3978/3981/10762/5431/7469/919/23511/5435/79720/4686/7316/10213/5709/9978/5433/5695/6872/2960/5611/567/4233/4331/3055/926/5714/6714/23279/8148/2966/9861/79902/9150/5715/2962/10898/3840/5711/6204/23327/5701/5688/5437/8812/5687/112755/999/5685/5683/5698/5708/3320/5692/2965/5686/5713/2534/5699/905/5710/2068/5439/5702/2071/6207/5719/3836/6827/5609/5704/6233/2885/3326/2968/5716/7514/1025/7311/2967/3932/1213/5610/6908/7040/7251/11198/6396/904/5694/7936/3304/6829/51497/2547/9045/2961/6416/5608/1022/5062/5432/55746/22916/5693/1234/5721/6137/6457/5696/8178/5691/2957/940/7314/25920 176 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 65/2027 79/10654 4.5835683557990005e-34 5.786755049196238e-33 2.8531321243080826e-33 10450/9318/6118/6917/5434/5440/902/27339/5430/5436/5982/404672/5441/7507/5438/3978/5431/2072/8450/5435/7316/9978/5433/4331/64708/5111/2966/10980/6119/5437/5427/1161/1642/2965/5985/10920/2033/2068/5439/10987/2071/5984/6233/2067/2873/2968/7311/2967/56949/3980/8533/5983/9716/6117/2073/5981/7874/5424/1022/5432/8178/50813/7314/51138/8451 65 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-180534 Vpu mediated degradation of CD4 50/2027 52/10654 5.007925295922822e-34 6.203213125987421e-33 3.0584648033689534e-33 5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/2027 52/10654 5.007925295922822e-34 6.203213125987421e-33 3.0584648033689534e-33 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/472/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5387390 Hh mutants abrogate ligand secretion 54/2027 59/10654 1.2439495116710882e-33 1.5264539334805033e-32 7.526108703174809e-33 5718/5689/5684/5720/5682/5700/122706/5707/10956/5690/5717/9491/23198/143471/5706/5705/10197/84447/7316/10213/5709/5695/5714/50846/7415/9861/5715/3549/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 54 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-180585 Vif-mediated degradation of APOBEC3G 51/2027 54/10654 1.427302348160809e-33 1.7352296140140205e-32 8.55546729160719e-33 60489/5718/5689/5684/8065/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 52/2027 56/10654 3.218942964528282e-33 3.8774973508492063e-32 1.9117816737661938e-32 5718/5689/5684/5720/5682/5700/122706/5707/10956/5690/5717/9491/23198/143471/5706/5705/10197/84447/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 52 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5633007 Regulation of TP53 Activity 98/2027 160/10654 2.2411016081045625e-32 2.6750603740375367e-31 1.3189258267792403e-31 1017/6118/80010/5563/83990/9156/5883/1763/1029/7486/10111/9219/6874/8445/207/22974/9212/204851/5982/5931/1460/6749/11200/545/472/580/8550/11073/7316/6872/116028/890/80196/1457/54971/983/6790/641/1108/8148/4194/5519/6119/5928/3364/1432/5571/10524/4683/144715/57459/1616/10000/5985/54815/2033/84126/900/1111/3066/3065/7157/1107/8900/5984/8626/5371/208/6233/5527/2475/672/5932/7311/7161/5562/5518/6908/8851/5300/7156/5983/6117/11198/5600/7874/1020/5608/5884/5810/53615/26013/83695/7314/4193/5515/1263/5516 98 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5658442 Regulation of RAS by GAPs 58/2027 68/10654 3.15556180164911e-32 3.732660041049803e-31 1.8403703252861099e-31 5718/5689/5684/4893/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/8452/7316/10213/5709/9978/5695/84078/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/399473/3845/5694/3265/200734/4763/5693/5721/5696/5691/7314/161742 58 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-446652 Interleukin-1 family signaling 90/2027 140/10654 3.589145591473393e-32 4.207632287146933e-31 2.0745531379287e-31 8454/1147/5718/5689/5777/8945/5684/351/5720/4790/5682/5604/26469/5783/5700/122706/5707/8767/29110/5690/3553/8878/5717/9491/23198/6500/143471/5706/5705/10197/8517/4615/7316/3565/10213/5709/9978/5695/79155/6774/7335/5970/4792/4793/5714/3606/8809/3146/9861/5715/64127/5711/3552/5701/5688/5687/23291/4088/5685/5683/5698/5708/5692/5686/5713/5699/57162/5771/5710/5702/5719/3654/7189/5704/6233/5716/7311/5599/7334/5694/3551/6416/5781/5608/5693/5721/5696/5691/4791/7314 90 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5696395 Formation of Incision Complex in GG-NER 43/2027 43/10654 7.139787773890881e-32 8.296054289485599e-31 4.090330210473118e-31 6118/902/404672/9557/6613/7507/7336/2072/8450/54778/7316/9978/85015/4331/1643/2966/6119/7341/10401/1642/2965/142/2068/2071/1069/7329/6233/2067/2968/7311/2967/6612/5887/6117/2073/7334/10038/1022/5886/7508/7314/8451/8554 43 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 48/2027 51/10654 1.8468262081171114e-31 2.127090185313831e-30 1.0487517248310466e-30 5718/5689/5684/5720/5682/5700/122706/5707/5690/51686/5717/9491/23198/143471/5706/5705/4947/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/4946/5685/5683/5698/5708/5692/5686/5713/5699/5710/4953/5702/5719/5704/5716/5694/5693/5721/5696/5691 48 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5683057 MAPK family signaling cascades 143/2027 294/10654 2.0625246519724064e-31 2.3548651026432777e-30 1.161055067243048e-30 5923/5718/2308/5689/2118/3725/815/5897/5684/4893/6464/5720/1437/3667/2309/5682/1844/5604/5525/5700/3815/122706/5707/5567/5526/8844/5690/57690/5594/5568/5717/9491/3315/23198/27327/409/143471/5706/2064/5705/10197/3337/192670/2260/5596/8550/8452/5528/4684/7316/10213/5709/673/9978/1950/3560/5695/2263/4233/983/5597/84078/5714/6714/4609/9861/5566/5715/5519/5711/2261/5701/5688/5687/3558/5685/5683/5698/5708/5692/5686/5713/2335/2534/408/80824/5699/5529/1445/5710/816/5702/192669/998/6708/5894/8556/1847/5719/23112/1742/5704/6233/5527/2885/5716/7514/7311/8997/5518/1956/1740/60/5896/399473/4140/1843/4343/3845/5694/3265/3559/26523/369/200734/4763/5781/8202/3569/5062/5693/5721/8682/5696/5691/5245/7529/7314/11221/161742/5595/5515/5516 143 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 67/2027 88/10654 3.0730843556952955e-31 3.478413585368899e-30 1.71501531647242e-30 5718/3303/5689/5684/5720/5682/5700/122706/5707/3842/207/5690/3184/5717/9491/3315/23198/26986/143471/5706/5705/10197/7534/8125/7538/7316/10213/5709/5695/9261/5714/9861/5715/5711/1432/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/1981/5699/5710/5702/5719/5704/6233/5716/7514/7311/5600/5694/3304/3312/8570/5693/5721/5696/5691/7529/7314/1994 67 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-169911 Regulation of Apoptosis 49/2027 53/10654 3.959827165718848e-31 4.443806041528929e-30 2.1909974871048957e-30 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5062/5693/5721/5696/5691/7314 49 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-4608870 Asymmetric localization of PCP proteins 55/2027 64/10654 5.682209198277975e-31 6.322661590965238e-30 3.117358302355892e-30 57154/5718/5689/2535/5684/144165/5720/5682/5700/122706/5707/1856/5690/5717/9491/23198/143471/5706/5705/10197/64750/7316/10213/5709/5695/5714/9861/5715/5711/8321/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/7855/5694/5693/5721/5696/5691/7314 55 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 61/2027 77/10654 2.8369936825850994e-30 3.130229164062383e-29 1.543344639354123e-29 5718/5689/5684/5720/5682/51512/5700/122706/5707/5690/10382/5717/9491/23198/143471/5706/9133/5705/10197/7316/10213/5709/891/5695/983/1026/5714/9861/5715/5711/5701/5688/5687/7846/5685/5683/5698/5708/3320/5692/22919/5686/5713/5699/5710/5702/7157/5719/5704/6233/3326/5716/7311/5347/84790/5694/5693/5721/5696/5691/7314 61 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5689603 UCH proteinases 72/2027 102/10654 6.488712362736155e-30 7.099732776893809e-29 3.5004895641076627e-29 5718/5689/5684/5720/3607/5682/5700/122706/5707/51377/83444/4738/5690/10445/5717/9491/23198/143471/5706/5705/10197/86/580/7316/10213/5709/5695/8314/11047/5714/9861/5715/283899/5711/29844/5701/4798/5688/79913/5687/7046/5685/5683/5698/5708/54617/5692/5686/5713/5699/5710/5702/9958/5719/54891/5704/6233/5716/7048/7311/93973/60/7040/8607/3054/5694/5693/5721/5696/5691/7314/7528 72 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1236974 ER-Phagosome pathway 63/2027 83/10654 2.6111351474520375e-29 2.833405329425227e-28 1.3969970558355835e-28 1147/3135/5718/5689/5684/5720/5682/5700/3107/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7099/8517/4615/7316/10213/5709/5695/567/5714/3106/9861/5715/5711/5701/5688/5687/5685/5683/929/5698/5708/5692/5686/5713/114609/5699/5710/5702/695/5719/5704/6233/5716/7311/3133/3134/5694/3551/3105/5693/5721/5696/5691/7314 63 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5678895 Defective CFTR causes cystic fibrosis 52/2027 61/10654 5.539691624730039e-29 5.961979592844706e-28 2.9395257542786665e-28 5718/5689/5684/5720/5682/5700/122706/5707/10956/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/11160/5694/5693/5721/5696/5691/7314 52 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5358346 Hedgehog ligand biogenesis 54/2027 65/10654 6.625221886557447e-29 7.015255110524134e-28 3.4588382514709933e-28 5718/5689/5684/5720/5682/5700/122706/5707/10956/5690/5717/9491/23198/143471/5706/5705/10197/84447/7316/10213/5709/5695/5714/50846/7415/9861/5715/3549/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 54 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 54/2027 65/10654 6.625221886557447e-29 7.015255110524134e-28 3.4588382514709933e-28 2176/3725/2963/6917/5434/5440/4436/902/5430/5436/404672/6749/545/472/5441/5438/5431/7469/5435/5433/4331/1643/2966/9150/2962/9656/5437/8812/2177/2965/51755/905/2068/5439/1111/2071/7157/55215/6827/2968/672/1025/2353/2967/1386/11198/904/7936/6829/51497/1022/5432/8178/25920 54 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5685942 HDR through Homologous Recombination (HRR) 55/2027 67/10654 6.753268108433363e-29 7.093632821098404e-28 3.4974820098412787e-28 6118/80010/83990/7516/5888/9156/5883/1763/7486/10111/675/5982/545/472/80198/580/11073/7316/116028/197342/641/79008/5111/10635/7517/6119/84464/3364/10524/4683/5427/144715/5889/5985/84126/1111/5984/79728/6233/548593/146956/672/5932/7311/7156/5890/5983/6117/5981/5884/5810/5424/348654/83695/7314 55 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9013694 Signaling by NOTCH4 62/2027 82/10654 1.0676448930561084e-28 1.112553765541802e-27 5.485393560814592e-28 8454/5718/5689/5684/5720/5682/5700/5707/207/5690/3280/5717/9491/6500/5706/5705/10197/10460/7534/7316/10213/5709/9978/5695/5714/5664/9861/5715/22938/8850/5711/5701/5688/1387/5687/4088/5685/5683/5698/5708/5692/5686/5713/2033/4855/55294/5699/5710/5702/5719/5704/6233/5716/7311/5694/4851/5693/5663/5721/5696/5691/7314 62 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 48/2027 54/10654 1.2500590989405613e-28 1.2923839345739818e-27 6.372037677981312e-28 10450/9318/6917/5434/5440/902/27339/5430/5436/404672/5441/7507/5438/5431/8450/5435/7316/9978/5433/4331/64708/2966/10980/5437/1161/1642/2965/10920/2033/2068/5439/10987/2071/6233/2873/2968/7311/2967/56949/8533/9716/7874/1022/5432/50813/7314/51138/8451 48 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5358351 Signaling by Hedgehog 89/2027 149/10654 2.4348263460180836e-28 2.4975992127513623e-27 1.2314294430930277e-27 8454/57154/5718/5689/8945/5684/5720/2735/339745/5682/5575/6608/5700/122706/5707/5567/10956/22873/1452/51684/5690/27152/10382/5568/5717/9491/23198/6500/409/79577/143471/5706/5705/10197/64750/5573/8452/2737/84447/7316/10213/5709/9978/5695/8650/5714/50846/7415/9861/5566/5715/2736/8405/3549/5711/2932/5701/5688/5687/7846/5576/5685/5683/5698/5708/5692/5686/5713/408/5699/5710/5702/83737/5719/5577/5704/6233/5716/7311/6469/23322/84790/5694/8481/5693/5721/5696/5691/7314 89 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 66/2027 92/10654 3.4431831606905954e-28 3.5045732480517454e-27 1.727913214055256e-27 1017/6118/80010/5563/83990/9156/5883/1763/7486/10111/6874/8445/22974/9212/204851/5982/1460/6749/11200/545/472/580/8550/11073/7316/6872/116028/890/1457/6790/641/8148/4194/6119/3364/1432/5571/10524/4683/144715/5985/84126/1111/7157/8900/5984/6233/672/5932/7311/5562/6908/8851/5300/7156/5983/6117/11198/5600/1020/5884/5810/83695/7314/4193/1263 66 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-166166 MyD88-independent TLR4 cascade 69/2027 99/10654 3.551201643601314e-28 3.559334166449256e-27 1.7549128250822085e-27 8454/1147/3665/3725/11035/8945/5601/351/4790/5606/5604/7321/8737/8767/29110/5594/6500/330/841/7099/8517/5528/7323/7316/79155/7335/5970/4792/4205/9261/4793/3146/7322/5519/64127/5598/1432/4208/329/23291/929/5602/2002/3661/3654/7189/5609/6233/10010/1385/2353/7311/6196/5518/7187/1386/8772/5599/5600/7334/3551/6416/5781/5608/4791/7314/5595/5515/5516 69 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 69/2027 99/10654 3.551201643601314e-28 3.559334166449256e-27 1.7549128250822085e-27 8454/1147/3665/3725/11035/8945/5601/351/4790/5606/5604/7321/8737/8767/29110/5594/6500/330/841/7099/8517/5528/7323/7316/79155/7335/5970/4792/4205/9261/4793/3146/7322/5519/64127/5598/1432/4208/329/23291/929/5602/2002/3661/3654/7189/5609/6233/10010/1385/2353/7311/6196/5518/7187/1386/8772/5599/5600/7334/3551/6416/5781/5608/4791/7314/5595/5515/5516 69 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-176187 Activation of ATR in response to replication stress 37/2027 37/10654 1.656687728761662e-27 1.6479022635333806e-26 8.124903932922029e-27 1017/4172/6118/5000/8318/23594/5883/8317/5982/63967/4173/545/4174/993/84515/4171/4998/6119/3364/10926/144715/5985/990/995/84126/4175/1111/5984/55388/23595/5983/6117/5001/5884/5810/4999/4176 37 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 45/2027 50/10654 1.927166718773588e-27 1.902533760714076e-26 9.380352449907058e-27 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/2209/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/5694/5693/5721/5696/5691 45 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5610787 Hedgehog 'off' state 74/2027 113/10654 2.023974592249522e-27 1.9831930146444943e-26 9.778039074889679e-27 8454/5718/5689/8945/5684/5720/2735/5682/5575/6608/5700/122706/5707/5567/1452/51684/5690/27152/10382/5568/5717/9491/23198/6500/143471/5706/5705/10197/5573/2737/7316/10213/5709/9978/5695/8650/5714/9861/5566/5715/2736/5711/2932/5701/5688/5687/7846/5576/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/83737/5719/5577/5704/6233/5716/7311/23322/84790/5694/8481/5693/5721/5696/5691/7314 74 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 66/2027 94/10654 2.6600218796526978e-027 2.587117576284439e-26 1.2755660475527556e-26 8454/1147/3665/3725/11035/8945/5601/351/4790/5606/5604/7321/8737/8767/29110/5594/6500/330/841/8517/5528/7323/7316/79155/7335/5970/4792/4205/9261/4793/3146/7322/5519/64127/5598/1432/4208/329/23291/5602/2002/3661/3654/7189/5609/6233/10010/1385/2353/7311/6196/5518/7187/1386/8772/5599/5600/7334/3551/6416/5608/4791/7314/5595/5515/5516 66 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-162909 Host Interactions of HIV factors 80/2027 129/10654 3.7196871391635235e-27 3.5911391277365485e-26 1.770594110360346e-26 60489/5718/5689/5905/8945/1173/3837/164/5684/5903/8065/5720/5682/3159/5700/122706/5707/5690/5717/9491/23198/6500/348995/143471/79023/5706/57122/5705/10197/10762/919/23511/7316/10213/5709/9978/5695/567/3055/926/5714/23279/9861/79902/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/2534/5699/5710/5702/5719/3836/5704/6233/5716/7514/1025/7311/3932/6396/904/5694/5062/55746/5693/5721/5696/5691/940/7314 80 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6782135 Dual incision in TC-NER 53/2027 66/10654 5.427831682151161e-27 5.202002188806186e-26 2.5648225005939025e-26 10450/6118/6917/5434/5440/902/27339/5430/5436/5982/404672/5441/7507/5438/5431/2072/8450/5435/7316/9978/5433/4331/5111/2966/6119/5437/5427/1161/1642/2965/5985/2033/2068/5439/2071/5984/6233/2067/2968/7311/2967/56949/5983/9716/6117/2073/5981/7874/5424/1022/5432/7314/8451 53 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 40/2027 42/10654 6.267531863901553e-27 5.963238650219376e-26 2.9401465265442067e-26 6118/80010/83990/7516/5888/9156/5883/1763/7486/10111/675/5982/545/472/580/11073/116028/641/10635/7517/6119/3364/10524/4683/144715/5889/5985/84126/1111/5984/79728/672/5932/7156/5890/5983/6117/5884/5810/83695 40 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5693532 DNA Double-Strand Break Repair 93/2027 166/10654 1.2880241027293704e-26 1.2166731272544343e-25 5.99874913425644e-26 1017/6118/80010/54962/25/3838/2237/5893/83990/151987/7516/5888/9156/5883/1763/7486/10111/7520/51720/675/5982/63967/5531/11200/545/472/6613/80198/7336/3981/580/11073/2072/5591/7316/116028/890/197342/8314/641/79008/5111/10635/7517/64421/9656/6119/84464/3364/22976/7341/10524/4683/5427/144715/5889/5985/84126/142/8914/1111/7157/8900/5984/7329/79728/8924/6233/2067/548593/146956/672/5932/7158/7311/6047/79184/3980/7156/5890/5983/6117/5599/7334/5981/10038/2547/5884/5810/5424/348654/83695/7314 93 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-351202 Metabolism of polyamines 49/2027 59/10654 2.5306946643558608e-26 2.3734300673566037e-25 1.170208435021695e-25 5718/5689/5684/5720/5682/5700/122706/5707/5690/51686/5717/9491/23198/143471/5706/5705/4947/10197/10213/5709/5695/79814/5714/9861/5715/5711/5701/5688/5687/4946/5685/5683/5698/5708/5692/5686/5713/5699/5710/4953/5702/5719/5704/5716/5694/5693/5721/5696/5691 49 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5696394 DNA Damage Recognition in GG-NER 37/2027 38/10654 5.1464831868631394e-26 4.792434343511561e-25 2.3628870174847565e-25 9318/83444/10445/86/8450/7316/9978/64708/1643/10980/283899/29844/4798/79913/1642/54617/10920/142/10987/1069/54891/6233/2873/7311/93973/60/8533/8607/5887/10038/5886/50813/7508/7314/51138/8451/7528 37 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5693538 Homology Directed Repair 82/2027 138/10654 5.549566763361891e-26 5.131395183305748e-25 2.5300100514955994e-25 1017/6118/80010/54962/25/2237/5893/83990/151987/7516/5888/9156/5883/1763/7486/10111/51720/675/5982/63967/5531/545/472/6613/80198/7336/580/11073/2072/7316/116028/890/197342/641/79008/5111/10635/7517/9656/6119/84464/3364/7341/10524/4683/5427/144715/5889/5985/84126/142/8914/1111/8900/5984/7329/79728/8924/6233/2067/548593/146956/672/5932/7158/7311/6047/79184/3980/7156/5890/5983/6117/7334/5981/10038/5884/5810/5424/348654/83695/7314 82 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-201681 TCF dependent signaling in response to WNT 114/2027 233/10654 1.719283093144207e-25 1.5786144764324082e-24 7.783283785673076e-25 5718/9070/5689/8945/2535/5684/7478/5720/7015/6597/5682/1499/5525/864/5700/139285/122706/5707/1856/5526/10023/207/8085/1454/1452/5690/4041/5717/5929/9491/23198/79577/1460/9101/143471/5706/7471/5705/10197/6657/7534/64750/8452/5528/7316/10213/5709/9978/5695/23401/89780/1457/8658/5714/6934/4609/59349/9861/81847/5715/5519/5711/2932/8321/5701/10524/5688/1387/5687/5685/5683/5698/5708/5692/5686/5713/324/2033/5699/8312/5529/5710/5702/3065/8313/5719/208/5704/6233/5527/1855/5716/1857/7514/4040/23072/90780/7311/7479/5518/7855/331/8607/25776/5694/80351/5693/5721/5696/5691/7314/4221/5515/5516 114 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 78/2027 129/10654 1.8059768274433883e-25 1.6466997044674783e-24 8.11897477249769e-25 8454/1147/3665/3725/11035/8945/5601/351/4790/5606/5604/7321/8737/8767/3684/29110/5594/4214/6500/330/51295/841/7099/8517/4615/5528/7323/7316/79155/7335/5970/4792/4205/9261/4793/8651/3146/7322/5519/64127/5598/1432/4208/329/23291/929/5602/114609/57162/2002/3661/695/3654/7189/5609/6233/10010/1385/2353/7311/6196/1759/5518/7187/1386/8772/5599/5600/7334/3551/6416/5781/5608/4791/7314/5595/5515/5516 78 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5685938 HDR through Single Strand Annealing (SSA) 36/2027 37/10654 2.672584287297635e-25 2.4200711511874447e-24 1.1932046001365122e-24 6118/80010/25/5893/83990/5888/9156/5883/1763/7486/10111/5982/545/472/580/11073/2072/116028/641/6119/3364/10524/4683/144715/5985/84126/5984/2067/672/5932/7156/5983/6117/5884/5810/83695 36 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-4086400 PCP/CE pathway 63/2027 92/10654 3.6860534291055672e-25 3.314923392065486e-24 1.634407252271034e-24 57154/5718/5689/1173/2535/5684/144165/5720/5682/5700/122706/5707/1856/5690/5717/9491/23198/409/143471/5706/7471/5705/10197/64750/7316/10213/5709/5695/5714/9861/5715/5711/8321/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/23002/5710/5702/5719/5704/6233/1855/5716/1857/7311/1213/387/7855/5694/5693/5721/5696/5691/7314 63 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 51/2027 65/10654 3.8102578947269025e-25 3.403311983521376e-24 1.677986827967809e-24 10450/6118/6917/5434/5440/902/27339/5430/5436/5982/404672/5441/5438/3978/5431/8450/5435/7316/9978/5433/4331/5111/2966/6119/5437/5427/1161/1642/2965/5985/2033/2068/5439/2071/5984/6233/2968/7311/2967/56949/3980/5983/9716/6117/5981/7874/5424/1022/5432/7314/8451 51 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8878171 Transcriptional regulation by RUNX1 115/2027 239/10654 6.512725337583294e-25 5.777843492058692e-24 2.8487383233383542e-24 1912/5718/9070/5689/25/5684/4773/5720/902/2624/1437/11091/6597/5682/5700/122706/5707/8535/8085/6045/9021/5690/2625/57690/5717/5929/9491/23198/27327/80012/1460/143471/5706/6598/5705/10197/6599/192670/200845/86/7316/10213/5709/865/5695/1457/4331/1911/6603/10413/5714/6714/2099/9861/5715/8850/5711/5701/5688/1387/84733/5687/3558/5588/5685/6604/5683/8289/5698/5708/5692/5686/5713/2033/6605/6602/57332/595/50943/5699/8312/5710/3458/5702/192669/3065/83737/861/5719/5371/23112/5704/6233/5716/7311/6688/7161/860/58508/25942/4343/5694/6601/3559/23466/26523/5781/1022/1493/5693/5721/5696/5691/7314/6015 115 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 37/2027 39/10654 8.204226291236927e-25 7.229630282143681e-24 3.564534912829891e-24 6118/80010/83990/7516/5888/9156/5883/1763/7486/10111/675/5982/545/472/580/11073/116028/641/6119/3364/10524/4683/144715/5889/5985/84126/1111/5984/672/5932/7156/5890/5983/6117/5884/5810/83695 37 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-113418 Formation of the Early Elongation Complex 33/2027 33/10654 1.3367921173658323e-24 1.1623894371532038e-23 5.731105975461742e-24 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/2967/7936/6829/51497/1022/5432/22916/25920 33 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 33/2027 33/10654 1.3367921173658323e-24 1.1623894371532038e-23 5.731105975461742e-24 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/2967/7936/6829/51497/1022/5432/22916/25920 33 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 78/2027 132/10654 1.490686593750517e-24 1.2876786168384401e-23 6.348838332109197e-24 1017/6118/80010/54962/25/5893/83990/151987/7516/5888/9156/5883/1763/7486/10111/51720/675/5982/63967/5531/545/472/6613/80198/7336/580/11073/2072/7316/116028/890/197342/641/79008/5111/10635/7517/9656/6119/84464/3364/7341/10524/4683/5427/144715/5889/5985/84126/8914/1111/8900/5984/7329/79728/8924/6233/2067/548593/146956/672/5932/7158/7311/6047/79184/7156/5890/5983/6117/7334/5981/5884/5810/5424/348654/83695/7314 78 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-72165 mRNA Splicing - Minor Pathway 44/2027 52/10654 1.9994621987427005e-24 1.7158783444112195e-23 8.460056774865916e-24 23451/2963/6635/5434/5440/6633/6432/6431/6632/24148/83443/5430/85437/4904/5436/51639/11325/6637/23450/5441/5438/5431/5435/10594/4686/5433/9343/9416/57819/2962/5437/23020/5439/9410/6636/6634/6427/6426/10907/5432/22916/10992/10262/6628 44 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1236975 Antigen processing-Cross presentation 65/2027 99/10654 2.50094808280045e-24 2.1323018394266176e-23 1.05132130616697e-23 1147/3135/5718/5689/5684/5720/653361/5682/5700/3107/122706/5707/5690/5717/9491/23198/2209/143471/5706/5705/10197/7099/8517/4615/7316/10213/5709/5695/567/5714/3106/9861/5715/5711/5701/5688/5687/5685/5683/929/5698/5708/5692/5686/5713/114609/5699/5710/5702/695/5719/5704/6233/5716/7311/3133/3134/5694/3551/3105/5693/5721/5696/5691/7314 65 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-909733 Interferon alpha/beta signaling 52/2027 69/10654 3.790112028338708e-24 3.210591673037886e-23 1.5829669931601396e-23 3135/3665/5777/51447/10379/3107/10410/9021/54739/4600/9636/2537/11274/8638/2634/3662/3394/3663/8519/3664/103/3434/6772/8651/3433/3659/3106/6041/25939/1958/4939/6059/3661/3669/4599/684/3133/3429/10581/3134/3452/4940/91543/3437/3456/6773/4938/5781/3430/3105/5696/3660 52 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2559583 Cellular Senescence 99/2027 195/10654 7.899760221294536e-24 6.648964852922901e-23 3.2782405776627125e-23 1912/1017/7014/3725/25913/9134/1019/5601/11065/4790/5606/3159/246184/7290/1029/7027/7321/2146/10111/8535/6045/8697/57690/5594/1027/27327/80012/898/5931/5925/7013/1051/472/192670/3576/3490/8550/8881/29855/7316/2114/890/6774/5970/1026/9261/1911/6667/51433/4194/5598/3552/5928/1432/10524/84733/4683/5602/23512/119504/57332/25842/192669/7157/8900/51529/23135/7324/64682/29945/10393/23112/5609/6233/51434/2353/51343/7311/6196/25906/4343/8726/29882/5599/5600/23466/4217/26523/3456/2113/6416/5608/54386/3569/7314/996/6015/5595/4193 99 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5689880 Ub-specific processing proteases 107/2027 220/10654 1.0051750565761087e-23 8.406336619646055e-23 4.144704390173027e-23 9960/5718/5689/5684/5720/7186/6314/5682/5700/122706/5707/991/8737/8237/5690/2625/9817/4303/5717/9491/23198/63967/409/6478/1080/330/3091/9101/143471/5706/5705/11274/55031/10197/8517/64750/7316/10213/5709/993/5695/890/4792/9738/8658/11047/5714/8678/1643/4609/9861/4194/4089/81847/5715/5711/5701/5688/9097/329/5687/7046/6502/4088/8078/5685/5683/5698/5708/5692/5686/5713/408/5728/5699/8312/5710/5702/7157/8900/9958/8313/8975/4087/10868/63891/5719/7189/57599/5704/6233/5716/7311/367/23770/8607/1540/29761/5694/80351/7874/5693/5721/5696/5691/7314/4193 107 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-3371556 Cellular response to heat stress 60/2027 89/10654 1.8188746307342482e-23 1.5115078418696634e-22 7.452417707538725e-23 3303/6118/6782/815/5903/573/7531/1915/116835/5594/9530/3308/10049/348995/10013/545/79023/472/57122/3337/3313/10808/10762/23511/3305/9261/9532/23279/7415/79902/91582/6119/26353/2932/1387/57805/259217/3310/3309/3320/2033/7266/816/9531/22824/3326/2475/3306/27000/23411/6117/6396/3304/3312/3297/57521/55746/10728/51182/5595 60 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 41/2027 48/10654 3.6599531619637574e-23 3.02233868028831e-22 1.4901497481679648e-22 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/22916/8178/25920 41 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2990846 SUMOylation 95/2027 188/10654 1.0152459997044742e-22 8.331362485074842e-22 4.107738748804287e-22 1912/10054/6095/7020/23468/7150/5905/5893/5903/55143/5468/1029/8204/7486/9112/8535/51564/1786/6045/9212/3619/80012/7153/10274/348995/79023/6613/57122/10735/2516/8517/332/3183/10762/5465/5885/23511/1655/5970/4792/3190/9759/9612/1911/6790/641/6672/5111/2099/23279/79902/9656/7341/1387/84733/10401/1616/2908/10055/2033/23512/8243/9126/57332/142/7428/3066/3065/23314/7157/1107/1069/7329/5987/5371/8924/672/7158/367/6612/9063/25942/6117/6396/11315/55746/8648/7421/6304/4791/10062/7508/6015/4193/8554 95 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 93/2027 182/10654 1.0282610611458813e-22 8.349633113503158e-22 4.116746995473959e-22 1912/6095/7020/23468/7150/5905/5893/5903/55143/5468/1029/8204/7486/9112/8535/51564/1786/6045/9212/3619/80012/7153/10274/348995/79023/6613/57122/10735/2516/8517/332/3183/10762/5465/5885/23511/1655/5970/4792/3190/9759/9612/1911/6790/641/6672/5111/2099/23279/79902/9656/7341/1387/84733/10401/1616/2908/2033/23512/8243/9126/57332/142/7428/3066/3065/23314/7157/1107/1069/7329/5987/5371/8924/672/7158/367/6612/9063/25942/6117/6396/11315/55746/8648/7421/6304/4791/10062/7508/6015/4193/8554 93 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9607240 FLT3 Signaling 120/2027 267/10654 1.0301908335015321e-22 8.349633113503158e-22 4.116746995473959e-22 5295/5923/5718/5689/815/5684/4893/6464/5290/5720/1437/3667/5682/1844/5291/5604/5525/5700/3815/122706/5707/5526/8844/5690/5594/5717/9491/23198/409/143471/5706/2064/5705/10197/2260/8452/6776/5528/4684/7316/10213/5709/673/9978/1950/3560/5695/2263/4233/3055/84078/5714/6714/9861/5715/5519/5711/2261/5701/5688/5687/3558/5685/5683/5698/5708/5692/5686/5713/2335/2534/408/80824/5699/5529/1445/5710/816/5702/6708/5894/1847/5719/208/1742/5704/6233/5527/2885/5716/7311/5518/1956/1740/60/399473/4140/1843/3845/6777/5694/3265/3559/369/200734/4763/5781/5693/5721/8682/5696/5691/5245/7529/7314/11221/161742/5595/5515/5516 120 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5619084 ABC transporter disorders 54/2027 77/10654 1.5975958632022855e-22 1.2868977720150925e-21 6.344988413751409e-22 5718/5689/5684/5720/5682/5700/122706/5707/10956/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/335/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/8647/5702/5719/5704/6233/5716/7311/11160/5694/5693/5721/5696/5691/7314 54 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-195258 RHO GTPase Effectors 137/2027 327/10654 2.9536595081066996e-22 2.3647286183805465e-21 1.1659182268842237e-21 220134/5905/55839/11130/25/79682/5903/10403/54908/6249/51517/55143/653361/1499/55055/25936/5525/9735/7531/80776/4690/1783/1058/4659/991/1856/401541/79019/5526/348235/80152/4771/10382/9212/5594/1063/8379/1027/3619/79172/1080/7533/2810/147841/348995/23421/79023/55920/57122/79980/64105/6232/7534/332/1780/23122/5528/5048/1781/5501/57405/8655/4085/5585/6714/23279/55166/79902/3796/54821/5519/9183/1432/2017/81565/2491/1062/699/7846/999/22919/91687/1060/995/3895/79003/23002/5529/51143/998/23028/695/83540/11004/1742/5527/1855/2885/10096/701/10097/1857/9055/7514/23380/9184/57120/367/5518/54820/5347/387/57551/60/5300/84790/84643/6396/5600/10095/23332/25909/64946/9793/10726/10109/81930/5062/55746/140735/5500/7529/4221/5595/5515/1778/5516 137 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-3858494 Beta-catenin independent WNT signaling 80/2027 146/10654 3.19994673103873e-22 2.546381853244759e-21 1.2554814925606501e-21 57154/5718/5689/1173/815/2535/5684/144165/5720/54331/5682/1499/4772/5700/122706/5707/1856/5690/5532/57690/5717/9491/23198/27327/409/143471/5706/7471/5705/10197/192670/64750/2775/5530/7316/10213/5709/5695/5714/6934/9861/5715/5711/8321/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5534/5699/23002/5710/5702/192669/5719/23112/5704/6233/1855/5716/1857/7311/1213/387/7855/4343/3845/5694/26523/5693/5721/5696/5691/7314 80 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-195721 Signaling by WNT 138/2027 331/10654 3.571286240755015e-22 2.8247583338020088e-21 1.3927336956653992e-21 8454/57154/5718/9070/5689/8945/1173/815/2535/5684/144165/7478/5720/54331/7015/6597/5682/1499/5525/864/4772/5700/139285/122706/5707/1856/5526/10023/207/8085/1454/1452/5690/5532/57690/4041/5717/5929/9491/23198/6500/27327/409/79577/1460/9101/143471/5706/7471/5705/10197/6657/192670/7534/64750/2775/8452/5530/5528/7316/10213/5709/9978/5695/23401/89780/1457/8658/5714/6934/4609/59349/9861/81847/5715/5519/5711/2932/8321/5701/10524/5688/1387/5687/5685/5683/5698/5708/5692/5686/5713/324/2033/5534/5699/23002/8312/5529/5710/5702/192669/3065/8313/5719/23112/208/5704/6233/5527/1855/5716/1857/7514/4040/23072/90780/7311/7479/5518/1213/387/7855/331/8607/4343/25776/3845/5694/26523/80351/5693/5721/5696/5691/7314/4221/5515/5516 138 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 61/2027 95/10654 3.785115806293634e-22 2.9582482462282985e-21 1.4585502637033741e-21 8454/1147/3725/8945/5601/351/4790/5606/5604/8767/5594/4214/6500/51295/7099/8517/4615/5528/7316/79155/7335/5970/4792/4205/9261/4793/8651/3146/5519/64127/5598/1432/4208/23291/929/5602/114609/57162/2002/695/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/7334/3551/6416/5608/4791/7314/5595/5515/5516 61 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 61/2027 95/10654 3.785115806293634e-22 2.9582482462282985e-21 1.4585502637033741e-21 8454/1147/3725/8945/5601/351/4790/5606/5604/8767/5594/4214/6500/51295/7099/8517/4615/5528/7316/79155/7335/5970/4792/4205/9261/4793/8651/3146/5519/64127/5598/1432/4208/23291/929/5602/114609/57162/2002/695/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/7334/3551/6416/5608/4791/7314/5595/5515/5516 61 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5684996 MAPK1/MAPK3 signaling 115/2027 255/10654 5.836772633461107e-22 4.534723353689014e-21 2.2358238365484778e-21 5923/5718/5689/815/5684/4893/6464/5720/1437/3667/5682/1844/5604/5525/5700/3815/122706/5707/5526/8844/5690/5594/5717/9491/23198/409/143471/5706/2064/5705/10197/2260/8452/5528/4684/7316/10213/5709/673/9978/1950/3560/5695/2263/4233/983/84078/5714/6714/9861/5715/5519/5711/2261/5701/5688/5687/3558/5685/5683/5698/5708/5692/5686/5713/2335/2534/408/80824/5699/5529/1445/5710/816/5702/6708/5894/1847/5719/1742/5704/6233/5527/2885/5716/7311/5518/1956/1740/60/399473/4140/1843/3845/5694/3265/3559/369/200734/4763/5781/3569/5693/5721/8682/5696/5691/5245/7529/7314/11221/161742/5595/5515/5516 115 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-167169 HIV Transcription Elongation 39/2027 46/10654 7.593912483238894e-22 5.796980866565504e-21 2.8581739150501347e-21 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/22916/8178/25920 39 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 39/2027 46/10654 7.593912483238894e-22 5.796980866565504e-21 2.8581739150501347e-21 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/22916/8178/25920 39 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 39/2027 46/10654 7.593912483238894e-22 5.796980866565504e-21 2.8581739150501347e-21 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/22916/8178/25920 39 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8943724 Regulation of PTEN gene transcription 46/2027 61/10654 1.593039479902059e-21 1.2090525070008112e-20 5.961176027622552e-21 1912/3725/6591/8841/5468/1822/23186/2146/5978/9112/9219/8535/51564/6045/5594/84232/80012/5931/1911/1108/57167/2122/7101/10014/1958/5928/84733/57459/54815/23512/57332/6615/3066/3065/7157/1107/23028/2475/57504/1386/8726/23466/53615/57521/6015/5595 46 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5673001 RAF/MAP kinase cascade 112/2027 249/10654 2.6527595236265193e-21 2.001766238230816e-20 9.86961347265765e-21 5923/5718/5689/815/5684/4893/6464/5720/1437/3667/5682/1844/5604/5525/5700/3815/122706/5707/5526/8844/5690/5594/5717/9491/23198/409/143471/5706/2064/5705/10197/2260/8452/5528/4684/7316/10213/5709/673/9978/1950/3560/5695/2263/4233/84078/5714/6714/9861/5715/5519/5711/2261/5701/5688/5687/3558/5685/5683/5698/5708/5692/5686/5713/2335/2534/408/80824/5699/5529/1445/5710/816/5702/6708/5894/1847/5719/1742/5704/6233/5527/2885/5716/7311/5518/1956/1740/60/399473/4140/1843/3845/5694/3265/3559/369/200734/4763/5693/5721/8682/5696/5691/5245/7529/7314/11221/161742/5595/5515/5516 112 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 56/2027 85/10654 3.0371965625347672e-21 2.2530164331119487e-20 1.1108390639065609e-20 8454/1147/3725/8945/5601/351/4790/5606/5604/8767/5594/4214/6500/51295/8517/4615/5528/7316/79155/7335/5970/4792/4205/9261/4793/3146/5519/64127/5598/1432/4208/23291/5602/57162/2002/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/7334/3551/6416/5608/4791/7314/5595/5515/5516 56 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 56/2027 85/10654 3.0371965625347672e-21 2.2530164331119487e-20 1.1108390639065609e-20 8454/1147/3725/8945/5601/351/4790/5606/5604/8767/5594/4214/6500/51295/8517/4615/5528/7316/79155/7335/5970/4792/4205/9261/4793/3146/5519/64127/5598/1432/4208/23291/5602/57162/2002/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/7334/3551/6416/5608/4791/7314/5595/5515/5516 56 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-975871 MyD88 cascade initiated on plasma membrane 56/2027 85/10654 3.0371965625347672e-21 2.2530164331119487e-20 1.1108390639065609e-20 8454/1147/3725/8945/5601/351/4790/5606/5604/8767/5594/4214/6500/51295/8517/4615/5528/7316/79155/7335/5970/4792/4205/9261/4793/3146/5519/64127/5598/1432/4208/23291/5602/57162/2002/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/7334/3551/6416/5608/4791/7314/5595/5515/5516 56 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 61/2027 98/10654 4.0439841276539234e-21 2.966341429949498e-20 1.4625405695425835e-20 8454/1147/3725/8945/5601/351/4790/5606/5604/8767/5594/4214/6500/51295/7099/8517/4615/5528/7316/79155/7335/5970/4792/4205/9261/4793/8651/3146/5519/64127/5598/1432/4208/23291/929/5602/114609/57162/2002/695/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/7334/3551/6416/5608/4791/7314/5595/5515/5516 61 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 61/2027 98/10654 4.0439841276539234e-21 2.966341429949498e-20 1.4625405695425835e-20 8454/1147/3725/8945/5601/351/4790/5606/5604/8767/5594/4214/6500/51295/7099/8517/4615/5528/7316/79155/7335/5970/4792/4205/9261/4793/8651/3146/5519/64127/5598/1432/4208/23291/929/5602/114609/57162/2002/695/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/7334/3551/6416/5608/4791/7314/5595/5515/5516 61 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 59/2027 93/10654 4.491168371063179e-21 3.25795805039003e-20 1.606320760804801e-20 8454/1147/3665/3725/8945/5601/351/4790/5606/5604/8767/5594/4214/6500/51295/7099/8517/4615/5528/7316/79155/7335/5970/4792/4205/9261/4793/3146/5519/64127/5598/1432/4208/23291/929/5602/57162/2002/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/7334/3551/6416/5608/4791/7314/5595/5515/5516 59 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-975155 MyD88 dependent cascade initiated on endosome 59/2027 93/10654 4.491168371063179e-21 3.25795805039003e-20 1.606320760804801e-20 8454/1147/3665/3725/8945/5601/351/4790/5606/5604/8767/5594/4214/6500/51295/7099/8517/4615/5528/7316/79155/7335/5970/4792/4205/9261/4793/3146/5519/64127/5598/1432/4208/23291/929/5602/57162/2002/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/7334/3551/6416/5608/4791/7314/5595/5515/5516 59 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-168898 Toll-like Receptor Cascades 81/2027 155/10654 9.768467488955388e-21 7.04725154560353e-20 3.4746139419939644e-20 8454/1147/3665/3725/11035/8945/5601/351/4790/5606/5604/7184/7321/8737/8767/3684/29110/5594/4214/6500/330/51295/841/7099/8517/4615/338/5528/7323/7316/79155/7335/5970/4792/4205/9261/4793/8651/3146/7322/5519/64127/5598/1432/4208/329/23291/929/5602/114609/57162/2002/3661/695/3654/7189/5609/6233/10010/1385/81622/2353/7311/6196/1759/5518/7187/1386/8772/5599/5600/7334/3551/6416/5781/5608/4791/7314/5595/5515/5516 81 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 58/2027 92/10654 1.5322915941399606e-20 1.0993982858501467e-19 5.4205310922983947e-20 8454/1147/3725/8945/5601/351/4790/5606/5604/8767/5594/4214/6500/51295/7099/8517/4615/5528/7316/79155/7335/5970/4792/4205/9261/4793/3146/5519/64127/5598/1432/4208/23291/929/5602/57162/2002/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/7334/3551/6416/5608/4791/7314/5595/5515/5516 58 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-450294 MAP kinase activation 46/2027 64/10654 4.440230425739357e-20 3.168490515758574e-19 1.5622092172938817e-19 8454/1147/3725/8945/5601/4790/5606/5604/8767/5594/6500/8517/5528/7316/79155/7335/4205/9261/5519/64127/5598/1432/4208/23291/5602/2002/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/7334/3551/6416/5608/7314/5595/5515/5516 46 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 59/2027 97/10654 9.402234763597715e-20 6.673045537623675e-19 3.290113445014279e-19 8454/1147/3665/3725/8945/5601/351/4790/5606/5604/8767/5594/4214/6500/51295/7099/8517/4615/5528/7316/79155/7335/5970/4792/4205/9261/4793/3146/5519/64127/5598/1432/4208/23291/929/5602/57162/2002/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/7334/3551/6416/5608/4791/7314/5595/5515/5516 59 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-167172 Transcription of the HIV genome 49/2027 73/10654 2.827465874974291e-19 1.9959476848608844e-18 9.840925371302713e-19 2963/6917/5434/5440/902/2959/5430/6874/5436/404672/6749/5441/5438/5431/7469/5435/4686/5433/6872/2960/4331/8148/2966/9150/2962/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/2967/6908/11198/904/7936/6829/51497/2961/1022/5432/22916/8178/2957/25920 49 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6783310 Fanconi Anemia Pathway 34/2027 40/10654 2.880467662838355e-19 2.0224887921426524e-18 9.971785041630107e-19 6118/2176/2178/545/80198/2072/353497/7316/197342/79008/6119/84464/9937/2177/29089/84126/7398/55215/64858/57599/6233/2067/548593/146956/7311/2189/55120/2187/6117/2175/2188/57697/7314/22909 34 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 29/2027 31/10654 3.3363136698009775e-19 2.330095664068449e-18 1.1488426130613671e-18 2535/7478/1499/5525/139285/1856/5526/10023/1452/4041/7471/5528/23401/89780/5519/2932/8321/324/8312/5529/5527/1855/1857/4040/7479/5518/7855/5515/5516 29 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5693568 Resolution of D-loop Structures through Holliday Junction Intermediates 30/2027 33/10654 6.020705472557381e-19 4.1769132899236385e-18 2.0594072820804407e-18 80010/83990/7516/5888/9156/1763/7486/10111/675/472/80198/580/116028/197342/641/79008/10635/7517/84464/10524/4683/5889/79728/548593/146956/672/5932/7156/5890/348654 30 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-3371453 Regulation of HSF1-mediated heat shock response 47/2027 69/10654 6.044276657162919e-19 4.1769132899236385e-18 2.0594072820804407e-18 3303/6118/6782/5903/573/7531/116835/5594/9530/3308/10049/348995/545/79023/472/57122/3337/3313/10808/10762/23511/3305/9261/9532/23279/79902/91582/6119/2932/57805/259217/3310/3309/7266/9531/22824/3306/27000/23411/6117/6396/3304/3312/3297/55746/51182/5595 47 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 62/2027 108/10654 6.924178590519785e-19 4.759919627933235e-18 2.346855791220539e-18 5295/6095/3605/7124/2308/596/2309/7412/7184/356/207/5292/5451/3684/9021/7422/3553/2625/4582/5743/3091/10538/4318/3726/4312/3383/6097/6657/6778/3576/332/3662/3565/6774/4314/1026/7133/3606/6772/8651/4609/1901/3552/79923/598/3320/4843/2335/595/7157/2353/604/6347/7040/6935/3687/7431/3312/3569/3162/3586/3598 62 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 25/2027 25/10654 8.535478307697928e-19 5.837022405212177e-18 2.877916205720519e-18 11065/246184/7321/991/8697/8881/7316/4085/51433/119504/51529/7324/64682/29945/10393/4751/6233/51434/701/7311/9184/25906/29882/7314/996 25 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5696400 Dual Incision in GG-NER 34/2027 41/10654 1.3797408368269033e-18 9.386527040174736e-18 4.627982626935073e-18 6118/5982/404672/9557/7507/2072/8450/7316/9978/5111/1643/2966/6119/5427/1642/2965/5985/142/2068/2071/5984/6233/2067/2968/7311/2967/5983/6117/2073/5981/10038/5424/7314/8451 34 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-112382 Formation of RNA Pol II elongation complex 43/2027 61/10654 2.481805920320622e-18 1.6710826530158854e-17 8.239193743574535e-18 2963/6917/5434/5440/902/5430/5436/9646/404672/79577/6749/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/22916/8178/25920 43 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-75955 RNA Polymerase II Transcription Elongation 43/2027 61/10654 2.481805920320622e-18 1.6710826530158854e-17 8.239193743574535e-18 2963/6917/5434/5440/902/5430/5436/9646/404672/79577/6749/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/22916/8178/25920 43 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-157118 Signaling by NOTCH 102/2027 235/10654 3.851499437093524e-18 2.5801116127060186e-17 1.2721117904471092e-17 8454/5718/5689/3725/5684/8841/5720/79885/142678/5682/9734/7027/55869/5700/5707/207/51564/4904/5690/57690/3280/5717/9491/6500/27327/409/3091/10013/5706/5705/10197/10460/192670/7534/7316/10213/5709/9978/1950/9611/5695/8650/1272/9759/9612/5714/6772/4609/5664/9861/10014/5715/5870/22938/8850/5711/5701/5688/1387/5687/4088/5685/5683/5698/5708/5692/5686/5713/2033/408/4855/595/55294/5699/5710/3002/5702/192669/3066/3065/7157/83737/861/5719/23112/5704/6233/5716/1385/7311/1956/4343/9787/5694/26523/4851/5693/5663/5721/5696/5691/7314 102 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5693537 Resolution of D-Loop Structures 30/2027 34/10654 4.1870749535353136e-18 2.790674829437496e-17 1.375928985532577e-17 80010/83990/7516/5888/9156/1763/7486/10111/675/472/80198/580/116028/197342/641/79008/10635/7517/84464/10524/4683/5889/79728/548593/146956/672/5932/7156/5890/348654 30 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-162587 HIV Life Cycle 76/2027 152/10654 4.454561981789795e-18 2.953959536409091e-17 1.4564357356728997e-17 5905/2963/2237/6917/5434/5440/5903/902/3159/2959/5430/6874/5436/7520/404672/6749/348995/79023/57122/5441/5438/3978/3981/10762/5431/7469/23511/5435/79720/4686/7316/5433/6872/2960/4331/23279/8148/2966/79902/9150/2962/23327/5437/8812/2965/905/2068/5439/2071/3836/6827/6233/2968/7514/1025/7311/2967/6908/7251/11198/6396/904/7936/6829/51497/2547/2961/1022/5432/55746/22916/1234/8178/2957/7314/25920 76 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-73856 RNA Polymerase II Transcription Termination 45/2027 67/10654 7.990981175866834e-18 5.2724413487000766e-17 2.599552194212168e-17 10921/53981/7919/6635/6432/8683/6431/6430/11051/79869/51585/6428/8106/29894/84967/6637/199746/81608/4686/9785/8189/11338/1477/10978/7307/6429/1478/10898/10250/10189/51362/9295/51692/23283/9939/6636/6634/10914/9775/6427/6426/22916/1479/55339/6628 45 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-72086 mRNA Capping 27/2027 29/10654 8.233792821572034e-18 5.405484987362041e-17 2.6651487290877904e-17 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/4686/5433/4331/2966/2962/5437/2965/2068/5439/2071/2968/2967/6829/1022/5432/22916 27 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-448424 Interleukin-17 signaling 47/2027 72/10654 8.556137607441043e-18 5.589158546552284e-17 2.7557081060886316e-17 8454/3605/1147/3725/8945/5601/4790/5606/5604/8767/5594/6500/8517/5528/7316/79155/7335/4205/9261/5519/64127/5598/1432/4208/23291/5602/2002/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/7334/3551/6416/5608/7314/5595/5515/5516 47 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 23/2027 23/10654 2.4030155388711435e-17 1.5542657155358678e-16 7.663233375191877e-17 2963/5434/5440/5430/5436/5441/5438/5431/7469/5435/4686/5433/9150/2962/5437/5439/6827/7936/6829/51497/5432/22916/25920 23 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 23/2027 23/10654 2.4030155388711435e-17 1.5542657155358678e-16 7.663233375191877e-17 11065/246184/7321/991/8697/8881/7316/891/983/51433/119504/51529/7324/64682/29945/10393/6233/51434/7311/25906/29882/7314/996 23 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-674695 RNA Polymerase II Pre-transcription Events 51/2027 84/10654 3.3202682253691765e-17 2.1370157744655535e-16 1.0536454894747388e-16 2963/6917/5434/5440/902/2959/5430/6874/5436/9646/404672/79577/6749/5441/5438/5431/7469/5435/4686/5433/6872/2960/4331/8148/2966/9150/2962/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/2967/6908/11198/904/7936/6829/51497/2961/1022/5432/22916/8178/2957/25920 51 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 49/2027 80/10654 8.317794721266962e-17 5.327446082450499e-16 2.626672017242199e-16 201626/3837/3838/5903/4600/348995/9636/79023/57122/11274/8638/25820/7706/10762/9470/23511/7316/4734/3434/6772/23279/79902/6041/3840/4939/6059/1981/1973/3661/7324/3836/9246/1977/51191/4599/6233/7311/7318/5610/5300/9775/4940/6396/7334/4938/55746/5495/7314/5595 49 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-388841 Costimulation by the CD28 family 45/2027 70/10654 1.0384831954051164e-16 6.619070075567562e-16 3.2635010995102027e-16 5295/3120/5777/9402/5290/5525/3117/3119/5526/207/3123/941/919/3115/5528/3122/9020/3113/6714/5519/4067/915/917/10000/2534/5529/1445/916/998/942/208/5527/2885/7525/2475/7409/3932/5518/3127/5781/5062/1493/940/5515/5516 45 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-170834 Signaling by TGF-beta Receptor Complex 46/2027 73/10654 1.496740418433087e-16 9.493817243491031e-16 4.680881552689289e-16 57154/7027/7321/51377/6497/10273/4738/51592/3726/64750/7323/54778/7316/9611/5501/9612/6667/4609/4089/22938/23327/23645/8812/7050/7046/4088/142/905/5494/3065/9958/9040/4087/5499/6233/7514/7048/1025/7311/9110/387/7040/904/5500/7314/4221 46 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 25/2027 27/10654 2.0091426560514426e-16 1.262203017892605e-15 6.223232100083794e-16 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/5433/4331/2966/2962/5437/2965/2068/5439/2071/2968/2967/6829/1022/5432 25 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 25/2027 27/10654 2.0091426560514426e-16 1.262203017892605e-15 6.223232100083794e-16 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/5433/4331/2966/2962/5437/2965/2068/5439/2071/2968/2967/6829/1022/5432 25 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5693607 Processing of DNA double-strand break ends 55/2027 98/10654 2.651274180776117e-16 1.6576776187424007e-15 8.173100858031639e-16 1017/6118/80010/54962/83990/151987/9156/5883/1763/7486/10111/51720/5982/63967/5531/545/472/6613/7336/580/11073/7316/116028/890/641/9656/6119/3364/7341/10524/4683/144715/5985/84126/8914/1111/8900/5984/7329/8924/6233/672/5932/7158/7311/6047/79184/7156/5983/6117/7334/5884/5810/83695/7314 55 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-389513 CTLA4 inhibitory signaling 21/2027 21/10654 6.75432657733166e-16 4.2030477706333984e-15 2.0722927638109108e-15 5525/5526/207/941/5528/6714/5519/4067/10000/2534/5529/942/208/5527/7525/3932/5518/5781/1493/5515/5516 21 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-162599 Late Phase of HIV Life Cycle 68/2027 139/10654 1.086065050670511e-15 6.726431186464062e-15 3.316434985910449e-15 5905/2963/6917/5434/5440/5903/902/2959/5430/6874/5436/404672/6749/348995/79023/57122/5441/5438/10762/5431/7469/23511/5435/79720/4686/7316/5433/6872/2960/4331/23279/8148/2966/79902/9150/2962/23327/5437/8812/2965/905/2068/5439/2071/6827/6233/2968/7514/1025/7311/2967/6908/7251/11198/6396/904/7936/6829/51497/2961/1022/5432/55746/22916/8178/2957/7314/25920 68 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-72187 mRNA 3'-end processing 39/2027 58/10654 1.198028560509691e-15 7.385030516193542e-15 3.641154261000544e-15 10921/53981/7919/6432/8683/6431/6430/11051/79869/51585/6428/8106/29894/199746/81608/4686/9785/8189/11338/1477/10978/7307/6429/1478/10898/10250/10189/51362/9295/51692/23283/9939/10914/9775/6427/6426/22916/1479/55339 39 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-75067 Processing of Capped Intronless Pre-mRNA 25/2027 28/10654 1.5357488662142247e-15 9.422608697847088e-15 4.6457725170769715e-15 53981/6635/11051/79869/51585/8106/29894/84967/6637/81608/4686/8189/1477/10978/1478/10898/51692/23283/6636/6634/10914/22916/1479/55339/6628 25 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 26/2027 30/10654 1.979918896306249e-15 1.2091318655116768e-14 5.961567300995561e-15 11065/7319/7321/65264/7320/10477/92912/7326/7316/7317/54926/55236/3093/7322/8078/29089/7328/7324/6233/7327/7311/55284/27338/7874/997/7314 26 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-167287 HIV elongation arrest and recovery 29/2027 36/10654 2.1981001383405545e-15 1.3300025261019116e-14 6.557514358862193e-15 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/7469/5435/5433/9150/2962/5437/8812/905/5439/6827/1025/11198/904/7936/6829/51497/5432/8178/25920 29 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-167290 Pausing and recovery of HIV elongation 29/2027 36/10654 2.1981001383405545e-15 1.3300025261019116e-14 6.557514358862193e-15 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/7469/5435/5433/9150/2962/5437/8812/905/5439/6827/1025/11198/904/7936/6829/51497/5432/8178/25920 29 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8939211 ESR-mediated signaling 93/2027 223/10654 2.5771117827439437e-15 1.5521778764875222e-14 7.652939383812292e-15 5295/3727/3725/2354/2963/3838/596/5434/5440/4893/6464/5290/54331/4316/2309/8204/5430/207/5436/5451/2625/57690/5594/1027/3315/27327/10274/4318/5441/10735/5481/192670/200845/5438/5431/5885/2100/5435/5433/1950/865/5469/1655/4314/6667/2289/6714/2099/4609/2962/8850/10524/1387/5437/10000/3320/2033/8243/4846/9126/595/8312/5439/192669/3065/2002/861/23028/23112/208/10498/3326/7514/1385/1025/2353/1386/6908/1956/3169/4343/3845/904/3265/26523/8202/5432/8648/3480/10728/2957/5595/7528 93 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 20/2027 20/10654 3.5787498168084085e-15 2.1358629588497456e-14 1.0530770992043882e-14 11065/246184/7321/991/8697/8881/4085/51433/119504/51529/7324/64682/29945/10393/51434/701/9184/25906/29882/996 20 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 20/2027 20/10654 3.5787498168084085e-15 2.1358629588497456e-14 1.0530770992043882e-14 11065/246184/7321/991/8697/8881/4085/51433/119504/51529/7324/64682/29945/10393/51434/701/9184/25906/29882/996 20 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 23/2027 25/10654 4.8399839164467775e-15 2.875519856241909e-14 1.4177614234888157e-14 1017/994/902/2305/51400/9133/891/993/890/4331/983/5519/995/5520/8900/28227/7514/5518/5347/7465/1022/5515/5516 23 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-382556 ABC-family proteins mediated transport 55/2027 103/10654 4.940521232295847e-15 2.9220289991011024e-14 1.4406925357334975e-14 5718/5689/5684/5720/5682/5700/122706/5707/10956/5690/5717/9491/23198/1080/23/143471/5706/5705/10197/10257/7316/10213/5709/335/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/11160/5694/5693/5721/5696/5691/7314 55 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-68962 Activation of the pre-replicative complex 27/2027 33/10654 1.0088651155148486e-14 5.940089222739893e-14 2.9287328111476606e-14 1017/4172/6118/5000/8318/23594/8317/4173/5557/5422/4174/84515/4171/51053/4998/6119/10926/5427/990/4175/81620/55388/23595/6117/5001/4999/4176 27 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-194315 Signaling by Rho GTPases 154/2027 455/10654 1.3307776230244392e-14 7.800495620674503e-14 3.845997359774579e-14 9181/220134/5905/55839/11130/25/79682/64333/5903/10403/54908/6249/51517/55143/653361/57522/1499/55055/25936/5525/9735/7531/80776/4690/1783/1058/4659/991/1856/401541/79019/5526/64411/10928/348235/80152/3633/4771/10382/9212/5594/1063/29127/8379/1027/3619/1894/79172/1080/7533/2810/147841/348995/23421/79023/55920/57122/79980/64105/6232/7534/332/1780/23122/5528/5048/1781/5501/57405/8655/4085/5585/6714/23279/55166/79902/3796/54821/5519/9183/1432/2017/81565/2491/1062/699/7846/999/396/22919/91687/1060/995/3895/79003/23002/5529/58504/397/51143/998/23028/695/83540/2/11004/1742/5527/1855/2885/7410/10096/701/10097/7409/1857/9055/7514/23380/9184/51306/57120/8997/367/5518/54820/5347/387/57551/60/5300/84790/84643/6396/5600/10095/23332/25909/64946/9793/10726/10109/81930/5062/55746/140735/5500/7529/4221/5595/5515/1778/9901/5516 154 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 19/2027 19/10654 1.895418540924172e-14 1.0963368036270652e-13 5.4054365994359654e-14 11065/246184/7321/991/8697/8881/51433/119504/51529/8556/7324/64682/29945/10393/51434/51343/25906/29882/996 19 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-176412 Phosphorylation of the APC/C 19/2027 19/10654 1.895418540924172e-14 1.0963368036270652e-13 5.4054365994359654e-14 11065/246184/7321/8697/8881/891/983/51433/119504/51529/7324/64682/29945/10393/51434/25906/5347/29882/996 19 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-77595 Processing of Intronless Pre-mRNAs 19/2027 19/10654 1.895418540924172e-14 1.0963368036270652e-13 5.4054365994359654e-14 53981/11051/79869/51585/8106/29894/81608/4686/8189/1477/10978/1478/10898/51692/23283/10914/22916/1479/55339 19 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5675221 Negative regulation of MAPK pathway 30/2027 40/10654 2.2973264961919754e-14 1.3229779339912562e-13 6.522879940711287e-14 4893/1844/5604/5525/5526/8844/5594/5528/7316/673/5519/80824/5529/5894/1847/6233/5527/7311/5518/4140/1843/3845/3265/369/7529/7314/11221/5595/5515/5516 30 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 23/2027 26/10654 3.437335219340388e-14 1.9708389270715848e-13 9.717127832196454e-14 80010/83990/7516/5888/9156/1763/7486/10111/675/472/580/116028/641/10635/7517/10524/4683/5889/79728/672/5932/7156/5890 23 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69473 G2/M DNA damage checkpoint 51/2027 95/10654 3.672447477360011e-14 2.0964884946842149e-13 1.0336637064422916e-13 6118/80010/83990/9156/5883/1763/7531/7486/10111/51720/5982/7533/2810/11200/545/472/7336/7534/580/11073/891/116028/983/641/9656/6119/3364/7341/10524/4683/144715/5985/995/84126/1111/7157/5984/8924/672/5932/7158/79184/7156/5983/6117/7334/7465/5884/5810/83695/7529 51 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 27/2027 34/10654 4.0120078119398335e-14 2.2705889039125005e-13 1.1195030872699627e-13 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/7469/5435/5433/9150/2962/5437/5439/6827/1025/11198/904/7936/6829/51497/5432/8178/25920 27 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 27/2027 34/10654 4.0120078119398335e-14 2.2705889039125005e-13 1.1195030872699627e-13 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/7469/5435/5433/9150/2962/5437/5439/6827/1025/11198/904/7936/6829/51497/5432/8178/25920 27 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5675482 Regulation of necroptotic cell death 18/2027 18/10654 1.0034679741796679e-13 5.65473583733006e-13 2.788040678204183e-13 7186/8737/356/355/330/841/7316/8797/329/8837/6233/7311/8772/331/8717/8743/8795/7314 18 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-376176 Signaling by ROBO receptors 88/2027 218/10654 1.4201172193116039e-13 7.968435508359555e-13 3.9287993246812256e-13 10921/5718/5689/6138/25/5684/5720/2107/6128/5682/57522/6129/4690/5700/122706/5707/5567/6152/5690/5532/5568/5717/9491/23198/6141/26986/23053/143471/6202/5706/5705/10197/6232/23122/4686/7316/10213/5709/9978/5695/5714/6714/9861/5566/5715/5711/6204/5701/5688/5687/5576/5685/1605/5683/5698/5708/5692/5686/5713/1981/5699/5710/5702/998/8453/6207/9939/5719/5704/6233/5716/23380/7311/8440/387/9775/5694/23332/9045/5062/22916/5693/5721/6137/5696/5691/7314/9901 88 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1169408 ISG15 antiviral mechanism 42/2027 72/10654 1.481019635950291e-13 8.2748033276712e-13 4.0798525245663115e-13 3837/3838/5903/4600/348995/9636/79023/57122/11274/25820/7706/10762/9470/23511/7316/4734/3434/6772/23279/79902/3840/1981/1973/3661/7324/3836/9246/1977/51191/4599/6233/7311/7318/5610/5300/9775/6396/7334/55746/5495/7314/5595 42 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 44/2027 78/10654 2.0257170010200326e-13 1.1270196704827554e-12 5.55671701885513e-13 1147/3665/351/7186/4790/7321/8737/29110/57506/4214/9636/841/7706/8517/7323/7316/5970/4792/4793/3093/3146/7322/1387/843/2033/83737/3661/9246/7189/51191/6233/10010/7311/7318/5094/7187/8772/5300/3452/1540/3551/3456/4791/7314 44 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-167161 HIV Transcription Initiation 32/2027 47/10654 2.629633165300381e-13 1.4267389859666942e-12 7.03446888499232e-13 2963/5434/5440/902/2959/5430/6874/5436/404672/5441/5438/5431/5435/5433/6872/2960/4331/8148/2966/2962/5437/2965/2068/5439/2071/2968/2967/6908/2961/1022/5432/2957 32 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-167162 RNA Polymerase II HIV Promoter Escape 32/2027 47/10654 2.629633165300381e-13 1.4267389859666942e-12 7.03446888499232e-13 2963/5434/5440/902/2959/5430/6874/5436/404672/5441/5438/5431/5435/5433/6872/2960/4331/8148/2966/2962/5437/2965/2068/5439/2071/2968/2967/6908/2961/1022/5432/2957 32 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-73776 RNA Polymerase II Promoter Escape 32/2027 47/10654 2.629633165300381e-13 1.4267389859666942e-12 7.03446888499232e-13 2963/5434/5440/902/2959/5430/6874/5436/404672/5441/5438/5431/5435/5433/6872/2960/4331/8148/2966/2962/5437/2965/2068/5439/2071/2968/2967/6908/2961/1022/5432/2957 32 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 32/2027 47/10654 2.629633165300381e-13 1.4267389859666942e-12 7.03446888499232e-13 2963/5434/5440/902/2959/5430/6874/5436/404672/5441/5438/5431/5435/5433/6872/2960/4331/8148/2966/2962/5437/2965/2068/5439/2071/2968/2967/6908/2961/1022/5432/2957 32 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-75953 RNA Polymerase II Transcription Initiation 32/2027 47/10654 2.629633165300381e-13 1.4267389859666942e-12 7.03446888499232e-13 2963/5434/5440/902/2959/5430/6874/5436/404672/5441/5438/5431/5435/5433/6872/2960/4331/8148/2966/2962/5437/2965/2068/5439/2071/2968/2967/6908/2961/1022/5432/2957 32 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 32/2027 47/10654 2.629633165300381e-13 1.4267389859666942e-12 7.03446888499232e-13 2963/5434/5440/902/2959/5430/6874/5436/404672/5441/5438/5431/5435/5433/6872/2960/4331/8148/2966/2962/5437/2965/2068/5439/2071/2968/2967/6908/2961/1022/5432/2957 32 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5213460 RIPK1-mediated regulated necrosis 19/2027 20/10654 3.110874616654759e-13 1.6740075293720076e-12 8.253614707690581e-13 11035/7186/8737/356/355/330/841/7316/8797/329/8837/6233/7311/8772/331/8717/8743/8795/7314 19 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5218859 Regulated Necrosis 19/2027 20/10654 3.110874616654759e-13 1.6740075293720076e-12 8.253614707690581e-13 11035/7186/8737/356/355/330/841/7316/8797/329/8837/6233/7311/8772/331/8717/8743/8795/7314 19 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6804757 Regulation of TP53 Degradation 27/2027 36/10654 4.707162033561723e-13 2.522654591863895e-12 1.243782878900305e-12 1017/1029/207/11200/472/7316/890/80196/983/4194/5519/1616/10000/900/7157/8900/208/6233/5527/2475/7311/5518/7874/7314/4193/5515/5516 27 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 47/2027 88/10654 4.767854119525221e-13 2.5447936824945587e-12 1.254698452506637e-12 8454/8945/22995/7531/10142/4659/11190/54801/84962/1454/10382/6500/9133/5048/1781/7316/891/8655/9738/983/1639/6790/5566/79959/84131/23291/7846/7283/3320/22919/11064/10733/1069/4751/5577/6233/7311/5518/54820/5347/23332/22897/9793/8481/5500/7314/1778 47 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-196299 Beta-catenin phosphorylation cascade 17/2027 17/10654 5.310392458382655e-13 2.8228928331402536e-12 1.391813919414163e-12 1499/5525/139285/5526/10023/1452/5528/23401/5519/2932/324/8312/5529/5527/5518/5515/5516 17 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 43/2027 77/10654 6.12113202690639e-13 3.240744496503262e-12 1.597833699723018e-12 1912/5893/5903/1029/7486/8535/51564/6045/80012/10274/348995/79023/6613/57122/10735/10762/5885/23511/1911/641/6672/23279/79902/9656/7341/84733/8243/9126/57332/142/1069/7329/5371/8924/672/6612/9063/6117/6396/55746/7508/6015/8554 43 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-73893 DNA Damage Bypass 32/2027 48/10654 6.455004901192783e-13 3.4037837089422186e-12 1.678219409948663e-12 6118/56852/7320/5982/9636/7706/8450/7316/9978/5111/7415/6119/83932/5427/1642/5985/25898/7398/5984/9246/57599/6233/7311/7318/5983/6117/5981/55666/5424/7314/51514/8451 32 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69190 DNA strand elongation 25/2027 32/10654 7.102412928925252e-13 3.730187270271542e-12 1.839151137384855e-12 4172/6118/2237/8318/1763/9837/5982/4173/3978/5557/5422/4174/84515/5111/4171/6119/5985/4175/5984/51659/5983/6117/5981/5424/4176 25 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 24/2027 30/10654 8.130943193266845e-13 4.253357933370266e-12 2.097097950874024e-12 6118/56852/7320/5982/8450/7316/9978/5111/6119/5427/1642/5985/7398/5984/57599/6233/7311/5983/6117/5981/5424/7314/51514/8451 24 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs 60/2027 130/10654 1.3381368181331036e-12 6.972117627812559e-12 3.437569520266745e-12 5718/5689/25/5684/5720/902/2624/5682/5700/122706/5707/5690/2625/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/865/5695/4331/10413/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/83737/861/5719/5704/6233/5716/7311/6688/7161/5694/1022/5693/5721/5696/5691/7314 60 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-190236 Signaling by FGFR 46/2027 87/10654 1.3654038592492521e-12 7.086068249779716e-12 3.4937523338393597e-12 5295/2963/5434/5440/4893/6464/5290/5430/5436/5594/3178/5441/2260/5438/5431/5435/4686/7316/673/5433/3185/2263/6714/2962/2261/5437/4670/5439/6233/2885/3187/7311/5518/53834/3845/3265/200734/5781/5432/22916/5725/7314/161742/5595/5515/5516 46 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 30/2027 44/10654 1.3978062147824968e-12 7.225667559092198e-12 3.5625811110287423e-12 7027/7321/6497/51592/3726/64750/7323/54778/7316/9611/9612/6667/4609/4089/22938/23327/8812/7050/4088/142/905/5494/3065/4087/6233/1025/7311/904/7314/4221 30 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6806003 Regulation of TP53 Expression and Degradation 27/2027 37/10654 1.4261766472700533e-12 7.330994074138553e-12 3.6145118495973145e-12 1017/1029/207/11200/472/7316/890/80196/983/4194/5519/1616/10000/900/7157/8900/208/6233/5527/2475/7311/5518/7874/7314/4193/5515/5516 27 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-400253 Circadian Clock 40/2027 70/10654 1.429348425726938e-12 7.330994074138553e-12 3.6145118495973145e-12 8454/6095/26224/8945/8841/1374/8204/28999/1454/1407/6500/3091/1408/5465/406/4209/7316/9611/5469/5501/4208/1387/2908/6604/1390/2033/79365/5499/10498/6233/1385/7311/23054/1386/9575/23411/23373/8648/5500/7314 40 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5654738 Signaling by FGFR2 41/2027 73/10654 1.6381661595945247e-12 8.369308044932338e-12 4.126447627076112e-12 5295/2963/5434/5440/4893/6464/5290/5430/5436/5594/3178/5441/5438/5431/5435/4686/7316/673/5433/3185/2263/6714/2962/5437/4670/5439/6233/2885/3187/7311/5518/3845/3265/5781/5432/22916/5725/7314/5595/5515/5516 41 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-73762 RNA Polymerase I Transcription Initiation 31/2027 47/10654 2.295814919867256e-12 1.1683740270487237e-11 5.760612712029223e-12 5434/5440/902/9112/9219/30834/404672/5931/5441/51082/5435/4331/1108/2966/8850/5928/5437/57459/2965/54815/2068/3066/3065/2071/1107/2968/57504/2967/6908/53615/1022 31 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 20/2027 23/10654 3.4987365705123785e-12 1.7736838289894802e-11 8.745063974253659e-12 7321/6497/51592/64750/7323/54778/7316/9611/9612/4089/23327/7050/4088/142/5494/3065/4087/6233/7311/7314 20 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-109606 Intrinsic Pathway for Apoptosis 33/2027 53/10654 4.864911612011268e-12 2.4567803640656904e-11 1.2113039033955183e-11 5533/596/10018/7531/1029/7027/842/207/5594/7533/2810/841/7534/8655/6774/54205/598/56616/836/10000/5534/3002/7157/8626/208/7161/840/331/5599/637/140735/7529/5595 33 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9010553 Regulation of expression of SLITs and ROBOs 71/2027 171/10654 6.811475603058575e-12 3.426615887668931e-11 1.6894767073527017e-11 10921/5718/5689/6138/5684/5720/2107/6128/5682/6129/5700/122706/5707/6152/5690/5717/9491/23198/6141/26986/23053/143471/6202/5706/5705/10197/6232/4686/7316/10213/5709/9978/5695/5714/9861/5715/5711/6204/5701/5688/5687/5685/1605/5683/5698/5708/5692/5686/5713/1981/5699/5710/5702/8453/6207/9939/5719/5704/6233/5716/7311/9775/5694/9045/22916/5693/5721/6137/5696/5691/7314 71 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 17/2027 18/10654 7.85281086898334e-12 3.935397202662262e-11 1.9403289210224005e-11 8792/4050/7186/8600/330/10673/9020/329/4049/8740/115650/7187/51330/958/8742/959/4055 17 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2173789 TGF-beta receptor signaling activates SMADs 24/2027 32/10654 9.67156692828111e-12 4.810139157891325e-11 2.3716162922220425e-11 57154/51377/10273/4738/64750/7316/5501/4089/23327/23645/7046/4088/9958/9040/4087/5499/6233/7514/7048/7311/9110/7040/5500/7314 24 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2871796 FCERI mediated MAPK activation 24/2027 32/10654 9.67156692828111e-12 4.810139157891325e-11 2.3716162922220425e-11 3725/9402/5601/4893/6464/2205/5594/4214/2206/6850/4067/5602/5609/2885/7410/7409/2353/3845/5599/3265/6416/5062/2207/5595 24 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 15/2027 15/10654 1.485413498496912e-11 7.223510827875724e-11 3.5615177449341165e-11 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 15/2027 15/10654 1.485413498496912e-11 7.223510827875724e-11 3.5615177449341165e-11 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 15/2027 15/10654 1.485413498496912e-11 7.223510827875724e-11 3.5615177449341165e-11 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 15/2027 15/10654 1.485413498496912e-11 7.223510827875724e-11 3.5615177449341165e-11 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 15/2027 15/10654 1.485413498496912e-11 7.223510827875724e-11 3.5615177449341165e-11 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 15/2027 15/10654 1.485413498496912e-11 7.223510827875724e-11 3.5615177449341165e-11 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2173788 Downregulation of TGF-beta receptor signaling 21/2027 26/10654 1.6477186582760938e-11 7.953877199693056e-11 3.9216214196586594e-11 57154/51377/10273/64750/7316/5501/23327/23645/7046/4088/9958/4087/5499/6233/7514/7048/7311/9110/7040/5500/7314 21 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6803529 FGFR2 alternative splicing 21/2027 26/10654 1.6477186582760938e-11 7.953877199693056e-11 3.9216214196586594e-11 2963/5434/5440/5430/5436/3178/5441/5438/5431/5435/4686/5433/3185/2962/5437/4670/5439/3187/5432/22916/5725 21 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9018519 Estrogen-dependent gene expression 64/2027 150/10654 1.805813925042457e-11 8.685105068061341e-11 4.282149851170662e-11 3727/3725/2354/2963/3838/596/5434/5440/8204/5430/5436/5451/2625/57690/27327/10274/5441/10735/192670/200845/5438/5431/5885/5435/5433/865/5469/1655/6667/2099/4609/2962/8850/10524/1387/5437/3320/2033/8243/9126/595/8312/5439/192669/3065/861/23028/23112/10498/3326/1025/2353/1386/6908/3169/4343/904/26523/8202/5432/8648/10728/2957/7528 64 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-110320 Translesion Synthesis by POLH 17/2027 19/10654 6.129568583995405e-11 2.926590382103988e-10 1.4429415039836073e-10 6118/5982/7316/5111/7415/6119/83932/5985/25898/5984/6233/7311/5983/6117/5981/55666/7314 17 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8851708 Signaling by FGFR2 IIIa TM 17/2027 19/10654 6.129568583995405e-11 2.926590382103988e-10 1.4429415039836073e-10 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2263/2962/5437/5439/5432/22916 17 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 14/2027 14/10654 7.851365933436228e-11 3.66862756960917e-10 1.8087994190160255e-10 5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 14 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-4839744 truncated APC mutants destabilize the destruction complex 14/2027 14/10654 7.851365933436228e-11 3.66862756960917e-10 1.8087994190160255e-10 5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 14 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-4839748 AMER1 mutants destabilize the destruction complex 14/2027 14/10654 7.851365933436228e-11 3.66862756960917e-10 1.8087994190160255e-10 5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 14 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5467337 APC truncation mutants have impaired AXIN binding 14/2027 14/10654 7.851365933436228e-11 3.66862756960917e-10 1.8087994190160255e-10 5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 14 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 14/2027 14/10654 7.851365933436228e-11 3.66862756960917e-10 1.8087994190160255e-10 5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 14 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 14/2027 14/10654 7.851365933436228e-11 3.66862756960917e-10 1.8087994190160255e-10 5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 14 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9006936 Signaling by TGF-beta family members 48/2027 102/10654 1.0122453473892288e-10 4.713043053624316e-10 2.3237435186426868e-10 4093/57154/7027/7321/51377/6497/10273/4738/51592/3726/64750/7323/54778/7316/9611/5501/9612/6667/4609/4089/22938/23327/23645/8812/7050/7046/4088/142/905/5494/3065/9958/9040/4087/5499/6233/7514/7048/1025/7311/9110/387/7040/904/5500/4090/7314/4221 48 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5673000 RAF activation 23/2027 32/10654 1.1244956513375681e-10 5.217183004262286e-10 2.572307329635873e-10 815/4893/5604/5525/5526/8844/5528/673/6714/5519/5529/816/5894/5527/5518/4140/3845/3265/369/5245/7529/5515/5516 23 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9006931 Signaling by Nuclear Receptors 103/2027 299/10654 1.1877735724146348e-10 5.491361621762026e-10 2.7074897962750204e-10 5295/3727/3725/2354/2963/3838/596/5434/5440/4893/6464/8841/112724/5290/54331/1374/4316/347/2309/5160/8204/5430/207/5436/5451/2625/57690/5594/1027/3315/27327/10274/4318/5441/10735/5481/192670/200845/5438/5431/5885/2100/5435/5433/1950/9611/865/5469/1655/4314/9612/6667/2289/6714/2099/4609/2962/8850/10524/1387/5437/10000/3320/2033/8243/4846/9126/595/8312/5439/192669/3065/2002/861/23028/23112/208/10498/3326/7514/1385/1025/2353/1738/1386/6908/1956/3169/4343/3845/904/3265/26523/29116/8202/5432/8648/3480/10728/2957/10062/5595/7528 103 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 146/2027 473/10654 1.761836600476749e-10 8.116812127810425e-10 4.001955712994278e-10 5295/5777/627/1173/2963/3643/9402/5434/5440/4893/8065/6464/5290/3667/653361/5291/1499/5604/26469/4690/3815/5567/5430/10273/207/5436/7422/2060/5594/10193/5568/3315/3178/9101/51741/4318/2064/5441/6778/2260/5438/5431/6696/6776/5528/9306/5435/4686/7316/673/5433/1950/9611/3185/6774/2263/11059/4205/4233/9261/4734/10768/10413/6772/6714/2099/8651/5664/5566/2962/5519/5598/1432/2261/4208/5437/4670/4067/4914/529/10000/3320/2335/2534/4846/3728/4803/5771/1445/5439/1111/5603/3630/2002/998/83737/208/1742/6233/2885/7525/1398/3187/7410/7006/2475/7409/1385/7311/6196/3932/3479/1759/5518/1213/8440/387/53834/1956/60/8851/5581/3845/5600/10750/6777/3265/6300/200734/1020/5781/5062/5432/3480/22916/5663/6457/5725/11140/7529/7314/161742/5595/5515/25920/5516 146 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 15/2027 16/10654 1.9552894819391053e-10 8.976556257993165e-10 4.425848477705373e-10 8454/1147/8945/4790/5604/6500/8517/7316/79155/23291/6233/7311/3551/6416/7314 15 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2559585 Oncogene Induced Senescence 23/2027 33/10654 3.042405473998089e-10 1.3918740025642828e-9 6.862568738341556e-10 1019/1029/7027/57690/5594/27327/5925/192670/7316/2114/6667/4194/192669/7157/23112/6233/7311/4343/26523/2113/7314/5595/4193 23 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-113510 E2F mediated regulation of DNA replication 18/2027 22/10654 3.3381379209007503e-10 1.5218663507439879e-9 7.503489844129976e-10 5000/23594/7027/5925/5557/5422/891/983/84515/5519/4998/28227/23595/5518/5001/4999/5515/5516 18 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 17/2027 20/10654 3.357965833753814e-10 1.525608698864622e-9 7.521941313999621e-10 1147/11035/7321/8737/330/8517/7323/7316/7335/7322/329/7189/6233/7311/7334/3551/7314 17 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 22/2027 31/10654 4.299688627693575e-10 1.9467210924695392e-9 9.598215992854985e-10 3725/5601/5594/5528/4205/9261/5519/5598/1432/4208/5602/2002/1385/2353/6196/5518/1386/5599/5600/5595/5515/5516 22 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-168638 NOD1/2 Signaling Pathway 24/2027 36/10654 5.193574972039357e-10 2.343355305253497e-9 1.155380216243156e-9 1147/842/8767/330/841/8517/7316/7335/64127/1432/329/5603/83737/3654/7189/6233/7311/5600/7334/1540/3551/6300/5608/7314 24 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1226099 Signaling by FGFR in disease 34/2027 63/10654 5.620806340050716e-10 2.5188118513606113e-9 1.2418882339253423e-9 5295/2963/8805/5434/5440/4893/11052/5290/5430/5436/9530/5441/2260/5438/5431/6776/5435/4686/5433/6774/2263/6772/2962/2261/5437/11064/5439/2885/11160/3845/6777/3265/5432/22916 34 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 34/2027 63/10654 5.620806340050716e-10 2.5188118513606113e-9 1.2418882339253423e-9 1147/3665/11035/5434/5440/6737/4790/1499/8737/29110/7520/5441/51082/8517/6778/4615/5591/5435/7316/5970/4792/4793/1387/5437/2033/22954/1660/3661/6233/7311/3551/2547/4791/7314 34 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69231 Cyclin D associated events in G1 27/2027 44/10654 6.948229703984668e-10 3.092551051298939e-9 1.5247676246032368e-9 8454/25/1019/902/1029/7027/1027/6500/5925/7316/4331/1026/6714/5519/4067/6502/595/5520/6233/28227/7311/5518/1163/1022/7314/5515/5516 27 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69236 G1 Phase 27/2027 44/10654 6.948229703984668e-10 3.092551051298939e-9 1.5247676246032368e-9 8454/25/1019/902/1029/7027/1027/6500/5925/7316/4331/1026/6714/5519/4067/6502/595/5520/6233/28227/7311/5518/1163/1022/7314/5515/5516 27 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 31/2027 55/10654 7.658758380732957e-10 3.3972803222643145e-9 1.6750129459995621e-9 1147/596/351/4790/842/8767/330/841/8517/7316/7335/5970/64127/1432/329/598/5603/83737/3654/7189/6233/3326/7311/5600/7334/1540/3551/6300/5608/4791/7314 31 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 28/2027 47/10654 8.877134785448017e-10 3.924470698078534e-9 1.9349416597733586e-9 8454/8841/79885/9734/55869/51564/3280/6500/3091/10013/7316/9978/9611/9759/9612/4609/10014/22938/8850/1387/2033/55294/3066/3065/6233/7311/4851/7314 28 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8852135 Protein ubiquitination 39/2027 79/10654 9.95155909681869e-10 4.384697011450651e-9 2.161854060241432e-9 11065/7319/7321/56852/65264/9646/7320/10477/92912/79577/7336/7326/5591/7323/7316/7317/54926/55236/56254/5111/7415/3093/7322/8078/118424/29089/7328/7324/6233/7327/7311/55284/27338/7334/7874/3105/997/6596/7314 39 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-937041 IKK complex recruitment mediated by RIP1 19/2027 25/10654 1.0267911764510048e-9 4.50895255745876e-9 2.223117667725288e-9 1147/11035/7321/8737/330/7099/8517/7323/7316/7335/7322/329/929/7189/6233/7311/7334/3551/7314 19 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1227986 Signaling by ERBB2 29/2027 50/10654 1.0769318861552298e-9 4.713371888406056e-9 2.3239056490718115e-9 5295/4893/8065/6464/5290/26469/10273/207/10193/9101/2064/7316/1950/6714/10000/3320/2534/208/6233/2885/7525/7311/387/1956/5581/3845/3265/11140/7314 29 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-432142 Platelet sensitization by LDL 15/2027 17/10654 1.367554470841273e-9 5.965445249882364e-9 2.9412344800398075e-9 5777/5525/5526/5175/2268/338/5528/5519/1432/5529/5527/5518/5781/5515/5516 15 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-187037 Signaling by NTRK1 (TRKA) 39/2027 80/10654 1.5883993236951216e-9 6.905855337787068e-9 3.4048992125217843e-9 5295/1173/4893/6464/5290/3667/5291/5604/5594/5528/673/6774/4205/9261/6714/5519/5598/1432/4208/4914/4803/5603/2002/2885/1398/1385/6196/1759/5518/1213/387/3845/5600/3265/6300/7529/5595/5515/5516 39 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1433557 Signaling by SCF-KIT 26/2027 43/10654 2.274452614031048e-9 9.855961327467874e-9 4.85943497526175e-9 5295/5777/9402/4893/5290/3815/4318/6776/9306/6774/6772/6714/8651/4067/2534/1111/2885/7525/7006/7409/3932/3845/10750/6777/3265/5781 26 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-72202 Transport of Mature Transcript to Cytoplasm 40/2027 84/10654 2.3634102569856655e-9 1.0207755484941378e-8 5.032885415672383e-9 10921/53981/7919/5903/6432/8683/6431/6430/6428/29894/199746/348995/79023/57122/10762/23511/81608/4686/9785/8189/11338/7307/6429/23279/79902/10898/10250/10189/51362/9295/51692/9939/1977/9775/6396/6427/6426/55746/22916/55339 40 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 24/2027 38/10654 2.6963801612898186e-9 1.1607695579585349e-8 5.7231192379404265e-9 1912/6597/8535/6045/80012/1460/6598/6599/86/865/1457/1911/6603/84733/6604/8289/2033/6605/6602/57332/861/6601/23466/6015 24 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-180024 DARPP-32 events 19/2027 26/10654 3.1317115810618813e-9 1.3437703614164215e-8 6.625396017726374e-9 5533/5575/84152/5567/5532/5568/5573/5530/5528/5566/5519/5576/5534/5499/5577/5518/1020/5515/5516 19 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-166520 Signaling by NTRKs 45/2027 101/10654 3.456592454439746e-9 1.4783406816545232e-8 7.288888597567096e-9 5295/627/1173/4893/6464/5290/3667/5291/5604/5594/5528/673/6774/4205/9261/6714/5519/5598/1432/4208/4914/2534/4803/5603/2002/2885/1398/1385/6196/1759/5518/1213/387/8851/3845/5600/3265/6300/1020/5781/7529/5595/5515/25920/5516 45 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1980143 Signaling by NOTCH1 36/2027 73/10654 4.536249860886653e-9 1.9275391803702836e-8 9.503640485250526e-9 8454/8841/79885/142678/9734/55869/51564/3280/6500/409/3091/10013/7316/9978/9611/8650/1272/9759/9612/4609/5664/10014/22938/8850/1387/2033/408/55294/3066/3065/83737/6233/7311/4851/5663/7314 36 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8854518 AURKA Activation by TPX2 36/2027 73/10654 4.536249860886653e-9 1.9275391803702836e-8 9.503640485250526e-9 22995/7531/10142/11190/54801/1454/22974/10382/3161/5048/1781/8655/9738/983/1639/6790/5566/79959/84131/7846/7283/3320/22919/11064/10733/1069/4751/5577/5518/54820/5347/23332/22897/9793/8481/1778 36 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5619115 Disorders of transmembrane transporters 66/2027 176/10654 6.031613672627705e-9 2.554680242632315e-8 1.259572974080149e-8 5718/5689/5684/5903/5720/5682/6559/5700/122706/5707/10956/5690/5717/9491/23198/1080/348995/143471/79023/5706/57122/5705/10197/10762/23511/7316/10213/5709/335/5695/5714/23279/7415/9861/79902/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/8647/5702/5719/5704/6233/5716/7311/11160/6396/5694/9197/55746/5693/5721/5696/5691/7314 66 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-193639 p75NTR signals via NF-kB 14/2027 16/10654 6.389273364449559e-9 2.6974649284637526e-8 1.3299722860505935e-8 4790/8767/8878/4615/7316/5970/4792/4803/3654/7189/6233/7311/3551/7314 14 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-4791275 Signaling by WNT in cancer 22/2027 34/10654 6.454723817014161e-9 2.716362939660126e-8 1.3392898608177155e-8 1499/5525/139285/5526/1452/4041/5528/89780/8658/6934/5519/2932/324/8312/5529/5527/4040/5518/7855/80351/5515/5516 22 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9614085 FOXO-mediated transcription 33/2027 65/10654 7.836544380423108e-9 3.287342738496978e-8 1.6208087418732845e-8 2308/2309/10018/356/207/4303/1027/2810/4287/1649/7534/114907/4800/1026/901/84676/4089/8850/1387/4088/2908/10000/2033/3630/3066/3065/6648/4087/208/604/23411/25942/7529 33 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 27/2027 48/10654 1.0178753362079053e-8 4.256274893124139e-8 2.0985361440424467e-8 5295/5777/6464/5290/1437/5291/7534/6776/7316/3560/3055/6850/5566/3558/4067/2534/6233/2885/7525/1398/7006/7409/7311/6777/3559/5781/7314 27 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-3371378 Regulation by c-FLIP 11/2027 11/10654 1.1566179678987601e-8 4.790660542116946e-8 2.362012453122157e-8 7186/8737/356/355/841/8797/8837/8772/8717/8743/8795 11 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5218900 CASP8 activity is inhibited 11/2027 11/10654 1.1566179678987601e-8 4.790660542116946e-8 2.362012453122157e-8 7186/8737/356/355/841/8797/8837/8772/8717/8743/8795 11 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69416 Dimerization of procaspase-8 11/2027 11/10654 1.1566179678987601e-8 4.790660542116946e-8 2.362012453122157e-8 7186/8737/356/355/841/8797/8837/8772/8717/8743/8795 11 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-114452 Activation of BH3-only proteins 20/2027 30/10654 1.4888265510508166e-8 6.147261828709818e-8 3.030878281682398e-8 5533/596/10018/7531/7027/207/7533/2810/7534/8655/10000/5534/7157/8626/208/7161/5599/637/140735/7529 20 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 30/2027 58/10654 2.1499584486406956e-8 8.739614374814963e-8 4.309025406270256e-8 8454/8841/79885/142678/9734/55869/51564/3280/6500/10013/7316/9978/9611/9759/9612/4609/5664/10014/22938/8850/1387/2033/55294/3066/3065/6233/7311/4851/5663/7314 30 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2644603 Signaling by NOTCH1 in Cancer 30/2027 58/10654 2.1499584486406956e-8 8.739614374814963e-8 4.309025406270256e-8 8454/8841/79885/142678/9734/55869/51564/3280/6500/10013/7316/9978/9611/9759/9612/4609/5664/10014/22938/8850/1387/2033/55294/3066/3065/6233/7311/4851/5663/7314 30 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 30/2027 58/10654 2.1499584486406956e-8 8.739614374814963e-8 4.309025406270256e-8 8454/8841/79885/142678/9734/55869/51564/3280/6500/10013/7316/9978/9611/9759/9612/4609/5664/10014/22938/8850/1387/2033/55294/3066/3065/6233/7311/4851/5663/7314 30 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 30/2027 58/10654 2.1499584486406956e-8 8.739614374814963e-8 4.309025406270256e-8 8454/8841/79885/142678/9734/55869/51564/3280/6500/10013/7316/9978/9611/9759/9612/4609/5664/10014/22938/8850/1387/2033/55294/3066/3065/6233/7311/4851/5663/7314 30 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 30/2027 58/10654 2.1499584486406956e-8 8.739614374814963e-8 4.309025406270256e-8 8454/8841/79885/142678/9734/55869/51564/3280/6500/10013/7316/9978/9611/9759/9612/4609/5664/10014/22938/8850/1387/2033/55294/3066/3065/6233/7311/4851/5663/7314 30 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-209560 NF-kB is activated and signals survival 12/2027 13/10654 2.350335881639992e-8 9.524663619115152e-8 4.696090211853785e-8 4790/8878/7316/5970/4792/4803/3654/7189/6233/7311/3551/7314 12 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 15/2027 19/10654 2.640211370399169e-8 1.0578299225018369e-7 5.215580248836572e-8 5295/4893/6464/5290/7316/1950/3320/6233/2885/7311/1956/3845/3265/11140/7314 15 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-202430 Translocation of ZAP-70 to Immunological synapse 15/2027 19/10654 2.640211370399169e-8 1.0578299225018369e-7 5.215580248836572e-8 3120/3117/3119/3123/919/3115/3122/3113/915/917/916/7535/26191/3932/3127 15 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 15/2027 19/10654 2.640211370399169e-8 1.0578299225018369e-7 5.215580248836572e-8 5295/4893/6464/5290/7316/1950/3320/6233/2885/7311/1956/3845/3265/11140/7314 15 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-199418 Negative regulation of the PI3K/AKT network 46/2027 110/10654 2.6425606594105294e-8 1.0578299225018369e-7 5.215580248836572e-8 5295/3643/5290/3667/5291/5525/3815/8870/5526/207/5594/930/941/2064/2260/4615/5528/2100/1950/2263/4233/6714/2099/5519/2261/10000/2534/5728/5529/3630/942/3654/7189/208/5527/2885/7409/3932/5518/1956/8394/5781/940/5595/5515/5516 46 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6807505 RNA polymerase II transcribes snRNA genes 35/2027 74/10654 2.9257794864530742e-8 1.1676439105510294e-7 5.757012907274487e-8 2963/5434/5440/55197/2959/5430/5436/5451/51585/5441/5438/5431/5435/4686/5433/2960/6667/2962/51808/5437/8812/905/5439/6827/1025/6908/51593/904/6829/2961/1022/5432/22916/8178/2957 35 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 23/2027 39/10654 3.7711648223075895e-8 1.500466488390868e-7 7.397978838019674e-8 6118/5982/9636/7706/7316/5111/7415/6119/83932/5427/5985/25898/5984/9246/6233/7311/7318/5983/6117/5981/55666/5424/7314 23 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-3371571 HSF1-dependent transactivation 17/2027 24/10654 4.655008364994142e-8 1.846533529678945e-7 9.10424596747145e-8 3303/815/3337/3305/26353/1387/3320/2033/816/3326/2475/3306/3304/3312/3297/57521/10728 17 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 21/2027 34/10654 4.7762592542879514e-8 1.888924217132554e-7 9.313251240922925e-8 7321/29110/57506/9636/7706/7323/7316/3093/7322/83737/3661/9246/51191/6233/7311/7318/5094/7187/5300/1540/7314 21 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-450341 Activation of the AP-1 family of transcription factors 10/2027 10/10654 6.103639886125125e-8 2.406630381526213e-7 1.1865776924188249e-7 3725/5601/5594/1432/5602/2353/1386/5599/5600/5595 10 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-73887 Death Receptor Signalling 54/2027 141/10654 6.326256630040944e-8 2.4869386093544186e-7 1.226173283162679e-7 9181/7124/1147/81858/8841/7186/4790/10018/7531/8737/8767/356/9530/8878/1894/355/330/23421/841/8517/4615/7316/5970/4792/5664/8797/7132/329/843/836/10616/396/8837/4803/3066/3065/3654/7189/6233/7410/7409/7311/8997/387/8772/331/5599/8717/1540/3551/8743/8795/5663/7314 54 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-202427 Phosphorylation of CD3 and TCR zeta chains 16/2027 22/10654 6.483992593879083e-8 2.541337992765145e-7 1.25299464107954e-7 3120/3117/3119/3123/5788/919/3115/3122/3113/915/917/1445/916/26191/3932/3127 16 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 20/2027 32/10654 7.543776065105914e-8 2.9391626034077344e-7 1.44914017805408e-7 7027/3726/54778/7316/6667/4609/4089/22938/8812/7050/4088/905/3065/4087/6233/1025/7311/904/7314/4221 20 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8941326 RUNX2 regulates bone development 20/2027 32/10654 7.543776065105914e-8 2.9391626034077344e-7 1.44914017805408e-7 25/8841/5594/3280/5925/10013/2737/865/4094/9759/10413/6714/4089/2736/3549/23314/7525/367/860/5595 20 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 43/2027 103/10654 7.925466856214286e-8 3.078739047990934e-7 1.5179576818971616e-7 5295/3643/5290/3667/5291/5525/3815/8870/5526/207/5594/930/941/2064/2260/4615/5528/2100/1950/2263/4233/6714/2099/5519/2261/2534/5529/3630/942/3654/7189/5527/2885/7409/3932/5518/1956/8394/5781/940/5595/5515/5516 43 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-380259 Loss of Nlp from mitotic centrosomes 33/2027 70/10654 8.003708393154377e-8 3.090843858885793e-7 1.5239259014829543e-7 22995/7531/10142/11190/54801/1454/10382/5048/1781/8655/9738/983/1639/5566/79959/84131/7846/7283/3320/22919/11064/10733/1069/4751/5577/5518/54820/5347/23332/22897/9793/8481/1778 33 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 33/2027 70/10654 8.003708393154377e-8 3.090843858885793e-7 1.5239259014829543e-7 22995/7531/10142/11190/54801/1454/10382/5048/1781/8655/9738/983/1639/5566/79959/84131/7846/7283/3320/22919/11064/10733/1069/4751/5577/5518/54820/5347/23332/22897/9793/8481/1778 33 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-168325 Viral Messenger RNA Synthesis 24/2027 43/10654 8.276004336919983e-8 3.1866257168257883e-7 1.5711506921456366e-7 2963/5434/5440/5903/5430/5436/348995/79023/57122/5441/5438/10762/5431/23511/5435/5433/23279/79902/2962/5437/5439/6396/5432/55746 24 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69186 Lagging Strand Synthesis 15/2027 20/10654 8.694346382010115e-8 3.337917192859439e-7 1.6457442366685813e-7 6118/2237/1763/5982/3978/5557/5422/5111/6119/5985/5984/5983/6117/5981/5424 15 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2559580 Oxidative Stress Induced Senescence 49/2027 125/10654 1.0985145492386021e-7 4.2051008838200715e-7 2.0733050415275137e-7 1912/3725/1019/5601/5606/1029/7027/2146/8535/6045/57690/5594/27327/80012/5931/192670/8550/7316/9261/1911/4194/5928/1432/84733/5602/23512/57332/192669/7157/23135/23112/5609/6233/2353/7311/4343/8726/5599/5600/23466/4217/26523/3456/6416/5608/7314/6015/5595/4193 49 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-3371511 HSF1 activation 11/2027 12/10654 1.1469459769992953e-7 4.3777327552327753e-7 2.1584203667520398e-7 6118/7531/1915/10013/7415/6119/3320/3326/6117/3297/10728 11 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 17/2027 25/10654 1.1962204887995436e-7 4.5525724689675386e-7 2.244624258159327e-7 6118/5982/3978/7316/5111/6119/5427/5985/5984/6233/7311/3980/5983/6117/5981/5424/7314 17 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-110312 Translesion synthesis by REV1 13/2027 16/10654 1.3017190134572594e-7 4.925524682044328e-7 2.428506577510131e-7 6118/5982/7316/5111/6119/5985/5984/6233/7311/5983/6117/5981/7314 13 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1295596 Spry regulation of FGF signaling 13/2027 16/10654 1.3017190134572594e-7 4.925524682044328e-7 2.428506577510131e-7 5594/7316/673/6714/6233/2885/7311/5518/5781/7314/5595/5515/5516 13 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-3371568 Attenuation phase 12/2027 14/10654 1.3580201442487364e-7 5.123794394823537e-7 2.5262625187930216e-7 3303/3337/3305/1387/3320/2033/3326/3306/3304/3312/3297/10728 12 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2871809 FCERI mediated Ca+2 mobilization 20/2027 33/10654 1.5726676331718071e-7 5.882941887050094e-7 2.900556588396046e-7 9402/6464/4773/2205/4772/5532/4775/2206/5530/6850/10768/4067/5534/695/2885/7410/7006/7409/3702/2207 20 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-389356 CD28 co-stimulation 20/2027 33/10654 1.5726676331718071e-7 5.882941887050094e-7 2.900556588396046e-7 5295/9402/5290/207/941/9020/6714/4067/10000/2534/998/942/208/2885/7525/2475/7409/3932/5062/940 20 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 20/2027 33/10654 1.5726676331718071e-7 5.882941887050094e-7 2.900556588396046e-7 1147/351/4790/8767/8517/7316/7335/5970/4792/4793/3146/64127/3654/7189/6233/7311/7334/3551/4791/7314 20 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-389948 PD-1 signaling 16/2027 23/10654 1.7530111802670827e-7 6.520407024619489e-7 3.214855750303432e-7 3120/5777/3117/3119/3123/919/3115/3122/3113/915/917/1445/916/3932/3127/5781 16 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 16/2027 23/10654 1.7530111802670827e-7 6.520407024619489e-7 3.214855750303432e-7 5601/8767/8517/7316/7335/64127/5602/3654/7189/5609/6233/7311/5599/7334/6416/7314 16 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69205 G1/S-Specific Transcription 18/2027 28/10654 1.8433413943087607e-7 6.837026131998313e-7 3.370963299137342e-7 26271/8318/7027/898/286826/5422/1876/983/5111/4998/5928/990/81620/3065/8900/7298/1719/6241 18 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5621575 CD209 (DC-SIGN) signaling 15/2027 21/10654 2.505656570058251e-7 9.267400215454883e-7 4.569247711151445e-7 4893/4790/5567/5568/5970/5566/1387/4067/2534/2033/5894/5971/3845/3265/5062 15 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-3899300 SUMOylation of transcription cofactors 24/2027 45/10654 2.6250125491293383e-7 9.654457918786612e-7 4.760084675555191e-7 1912/8204/8535/6045/80012/6613/1655/9612/1911/7341/1387/84733/10401/1616/2033/57332/7329/6612/9063/25942/11315/8648/6015/8554 24 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-4615885 SUMOylation of DNA replication proteins 24/2027 45/10654 2.6250125491293383e-7 9.654457918786612e-7 4.760084675555191e-7 7150/5905/5903/55143/9212/3619/7153/348995/79023/6613/57122/332/10762/23511/6790/5111/23279/79902/7341/10401/7329/6612/6396/55746 24 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2219528 PI3K/AKT Signaling in Cancer 41/2027 101/10654 3.931563600930571e-7 1.4419393877155977e-6 7.109413744699503e-7 5295/1147/2308/5290/3667/2309/5291/842/3815/207/4303/1027/930/941/2064/6199/2260/2100/1950/2263/4233/1026/6714/2099/2932/2261/10000/2534/5728/942/208/2885/2475/7409/1385/3932/2931/1956/5781/940/4193 41 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 16/2027 24/10654 4.328031867802412e-7 1.5720472748094212e-6 7.750904509622755e-7 6118/2237/1763/5982/3978/5557/5422/5111/6119/5427/5985/5984/5983/6117/5981/5424 16 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-450302 activated TAK1 mediates p38 MAPK activation 16/2027 24/10654 4.328031867802412e-7 1.5720472748094212e-6 7.750904509622755e-7 5606/8767/8517/7316/7335/9261/64127/1432/3654/7189/6233/7311/5600/7334/5608/7314 16 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8940973 RUNX2 regulates osteoblast differentiation 16/2027 24/10654 4.328031867802412e-7 1.5720472748094212e-6 7.750904509622755e-7 25/8841/5594/3280/5925/10013/2737/865/4094/10413/6714/23314/7525/367/860/5595 16 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 27/2027 55/10654 4.334204977006935e-7 1.5720472748094212e-6 7.750904509622755e-7 3303/1783/10382/10294/3337/1780/1781/3305/8655/1639/2289/7846/2908/3320/51143/3301/10963/3326/3306/367/84790/3304/3312/55466/140735/10728/1778 27 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5655253 Signaling by FGFR2 in disease 23/2027 43/10654 4.352869846885408e-7 1.5744677986117191e-6 7.762838787398946e-7 5295/2963/5434/5440/4893/5290/5430/5436/5441/5438/5431/5435/4686/5433/2263/2962/5437/5439/2885/3845/3265/5432/22916 23 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-4551638 SUMOylation of chromatin organization proteins 32/2027 71/10654 4.548765864791683e-7 1.6280582951790032e-6 8.027064188360019e-7 1912/23468/5903/8535/6045/80012/348995/79023/6613/57122/10762/23511/9759/1911/23279/79902/7341/84733/23512/57332/3066/3065/23314/1107/7329/6612/9063/6396/55746/6304/6015/8554 32 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 13/2027 17/10654 4.56302705731815e-7 1.6280582951790032e-6 8.027064188360019e-7 7186/8737/356/355/841/7099/8797/929/8837/8772/8717/8743/8795 13 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5655862 Translesion synthesis by POLK 13/2027 17/10654 4.56302705731815e-7 1.6280582951790032e-6 8.027064188360019e-7 6118/5982/7316/5111/6119/5985/5984/6233/7311/5983/6117/5981/7314 13 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5656121 Translesion synthesis by POLI 13/2027 17/10654 4.56302705731815e-7 1.6280582951790032e-6 8.027064188360019e-7 6118/5982/7316/5111/6119/5985/5984/6233/7311/5983/6117/5981/7314 13 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8934593 Regulation of RUNX1 Expression and Activity 13/2027 17/10654 4.56302705731815e-7 1.6280582951790032e-6 8.027064188360019e-7 57690/27327/192670/865/6714/595/192669/861/5371/23112/4343/26523/5781 13 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5656169 Termination of translesion DNA synthesis 19/2027 32/10654 5.083001442763277e-7 1.808666909037448e-6 8.917546390812768e-7 6118/5982/9636/7706/7316/5111/6119/5427/5985/5984/9246/6233/7311/7318/5983/6117/5981/5424/7314 19 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-111447 Activation of BAD and translocation to mitochondria 12/2027 15/10654 5.60616007680614e-7 1.9787333819479735e-6 9.756051067447018e-7 5533/596/7531/207/7533/2810/7534/10000/5534/208/637/7529 12 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-937039 IRAK1 recruits IKK complex 12/2027 15/10654 5.60616007680614e-7 1.9787333819479735e-6 9.756051067447018e-7 1147/8517/7316/7335/57162/3654/7189/6233/7311/7334/3551/7314 12 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 12/2027 15/10654 5.60616007680614e-7 1.9787333819479735e-6 9.756051067447018e-7 1147/8517/7316/7335/57162/3654/7189/6233/7311/7334/3551/7314 12 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-209543 p75NTR recruits signalling complexes 11/2027 13/10654 6.162464115593422e-7 2.1634533111695623e-6 1.0666803915254588e-6 8767/8878/4615/7316/4803/3654/7189/6233/7311/3551/7314 11 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 11/2027 13/10654 6.162464115593422e-7 2.1634533111695623e-6 1.0666803915254588e-6 7531/7533/2810/11200/7534/891/983/995/1111/7465/7529 11 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 15/2027 22/10654 6.485493664351856e-7 2.2587408968949566e-6 1.113661483617588e-6 4000/3725/351/994/2309/10018/7531/356/7001/993/995/6648/8851/5052/1020 15 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8863678 Neurodegenerative Diseases 15/2027 22/10654 6.485493664351856e-7 2.2587408968949566e-6 1.113661483617588e-6 4000/3725/351/994/2309/10018/7531/356/7001/993/995/6648/8851/5052/1020 15 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-912631 Regulation of signaling by CBL 15/2027 22/10654 6.485493664351856e-7 2.2587408968949566e-6 1.113661483617588e-6 5295/5290/5291/7316/3055/6850/4067/2534/6233/2885/7525/1398/7409/7311/7314 15 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 35/2027 82/10654 6.691378481837962e-7 2.3181477431802757e-6 1.1429517473490757e-6 10844/22995/7531/10142/11190/54801/1454/10382/5048/1781/8655/9738/983/1639/5566/79959/84131/7846/7283/3320/22919/10426/11064/10733/1069/4751/5577/5518/54820/5347/23332/22897/9793/8481/1778 35 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-380287 Centrosome maturation 35/2027 82/10654 6.691378481837962e-7 2.3181477431802757e-6 1.1429517473490757e-6 10844/22995/7531/10142/11190/54801/1454/10382/5048/1781/8655/9738/983/1639/5566/79959/84131/7846/7283/3320/22919/10426/11064/10733/1069/4751/5577/5518/54820/5347/23332/22897/9793/8481/1778 35 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5689896 Ovarian tumor domain proteases 21/2027 38/10654 6.731228280531311e-7 2.3258165085098977e-6 1.146732795713783e-6 7321/8737/8767/57506/7706/8517/7316/79155/983/2099/7415/64127/324/5728/7157/7189/6233/7311/7187/387/7314 21 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-180786 Extension of Telomeres 18/2027 30/10654 8.211929796436339e-7 2.815212486350108e-6 1.3880271608652873e-6 6118/2237/7015/1763/5982/3978/5557/5422/5111/6119/5427/5985/5984/8607/5983/6117/5981/5424 18 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 18/2027 30/10654 8.211929796436339e-7 2.815212486350108e-6 1.3880271608652873e-6 7124/1147/81858/7186/8737/330/8517/7316/7132/329/10616/6233/7311/331/8717/1540/3551/7314 18 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6804758 Regulation of TP53 Activity through Acetylation 18/2027 30/10654 8.211929796436339e-7 2.815212486350108e-6 1.3880271608652873e-6 9219/207/5931/1108/5928/57459/10000/54815/2033/3066/3065/7157/1107/5371/208/5300/5608/53615 18 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5357905 Regulation of TNFR1 signaling 19/2027 33/10654 9.847025898637394e-7 3.3573771470546603e-6 1.6553388747653957e-6 7124/1147/81858/7186/8737/330/841/8517/7316/7132/329/10616/6233/7311/331/8717/1540/3551/7314 19 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9022692 Regulation of MECP2 expression and activity 19/2027 33/10654 9.847025898637394e-7 3.3573771470546603e-6 1.6553388747653957e-6 815/8841/9212/57690/27327/192670/9611/9612/5566/3064/816/192669/3066/3065/23112/1385/25942/4343/26523 19 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 16/2027 25/10654 9.895696541585329e-7 3.3573771470546603e-6 1.6553388747653957e-6 5594/5528/4205/9261/5519/5598/1432/4208/2002/1385/6196/5518/5600/5595/5515/5516 16 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 16/2027 25/10654 9.895696541585329e-7 3.3573771470546603e-6 1.6553388747653957e-6 1147/2308/2309/842/207/4303/1027/6199/1026/2932/10000/208/2475/1385/2931/4193 16 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-350054 Notch-HLH transcription pathway 17/2027 28/10654 1.3218740788341015e-6 4.473249137910246e-6 2.2055142660959644e-6 8841/79885/9734/55869/51564/10013/9611/9759/9612/10014/22938/8850/1387/4855/3066/3065/4851 17 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-187687 Signalling to ERKs 19/2027 34/10654 1.8346375658977916e-6 6.192491321397944e-6 3.0531784684809687e-6 4893/6464/5604/5594/673/9261/6714/1432/4914/4803/5603/2885/1398/3845/5600/3265/6300/7529/5595 19 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 42/2027 110/10654 1.9796341762661695e-6 6.664768393429437e-6 3.286032438336557e-6 1017/3725/1019/11065/4790/246184/1029/7321/8697/5594/1027/1051/3576/3490/8881/7316/890/6774/5970/1026/51433/5598/3552/119504/8900/51529/7324/64682/29945/10393/6233/51434/2353/51343/7311/6196/25906/29882/3569/7314/996/5595 42 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 32/2027 75/10654 2.0176410974791664e-6 6.77535232989807e-6 3.340555323595874e-6 10921/7919/5903/6432/8683/6431/6430/6428/199746/348995/79023/57122/10762/23511/4686/9785/11338/7307/6429/23279/79902/10250/10189/51362/9295/9939/9775/6396/6427/6426/55746/22916 32 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-110373 Resolution of AP sites via the multiple-nucleotide patch replacement pathway 16/2027 26/10654 2.118136174025434e-6 7.094675501263763e-6 3.4979960983502742e-6 6118/2237/328/5982/3978/5111/6119/5427/5985/142/5984/5983/6117/5981/10038/5424 16 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8986944 Transcriptional Regulation by MECP2 28/2027 62/10654 2.245564882213656e-6 7.502357990703639e-6 3.699002015699474e-6 627/815/8841/5468/9212/57690/27327/6657/192670/9611/4233/9612/2289/5566/4208/3064/5728/816/192669/3066/3065/3654/23112/1385/25942/4343/26523/2891 28 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 14/2027 21/10654 2.352781644269793e-6 7.820765313737313e-6 3.855991235778609e-6 1147/11035/4790/8737/29110/8517/4615/5970/4792/4793/1660/3661/3551/4791 14 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 14/2027 21/10654 2.352781644269793e-6 7.820765313737313e-6 3.855991235778609e-6 6118/2237/328/5982/3978/5111/6119/5427/5985/5984/5983/6117/5981/5424 14 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-198323 AKT phosphorylates targets in the cytosol 11/2027 14/10654 2.3778758677190653e-6 7.884219733119022e-6 3.8872771362233525e-6 1147/842/207/1027/1026/2932/10000/208/2931/23608/4193 11 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-186763 Downstream signal transduction 17/2027 29/10654 2.628556979300471e-6 8.671596265883213e-6 4.275489400343268e-6 5295/4893/5290/5291/4690/6778/6776/6774/6772/6714/2885/1398/8440/3845/6777/3265/5781 17 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8863795 Downregulation of ERBB2 signaling 17/2027 29/10654 2.628556979300471e-6 8.671596265883213e-6 4.275489400343268e-6 8065/26469/10273/207/10193/9101/2064/7316/1950/10000/3320/208/6233/7311/1956/11140/7314 17 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-176974 Unwinding of DNA 10/2027 12/10654 2.7609585556036868e-6 9.062846458769102e-6 4.468393451832283e-6 4172/8318/9837/4173/4174/84515/4171/4175/51659/4176 10 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2029481 FCGR activation 10/2027 12/10654 2.7609585556036868e-6 9.062846458769102e-6 4.468393451832283e-6 2268/2209/919/3055/6850/6714/4067/917/2534/7525 10 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-73863 RNA Polymerase I Transcription Termination 18/2027 32/10654 3.0271387590247227e-6 9.911803467829079e-6 4.886967677648522e-6 5434/5440/902/30834/404672/5441/51082/5435/4331/2966/5437/2965/2068/2071/2968/2967/6908/1022 18 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8953750 Transcriptional Regulation by E2F6 19/2027 35/10654 3.2992548002585414e-6 1.0775924260545932e-5 5.313018335058925e-6 23468/5888/7027/2146/8317/6045/80012/5931/4149/1876/1911/5928/23512/1111/672/5932/8726/6015/6241 19 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-4570464 SUMOylation of RNA binding proteins 23/2027 47/10654 3.3161741963538325e-6 1.0804309478443132e-5 5.327013532082035e-6 1912/5903/8535/6045/80012/348995/79023/6613/57122/3183/10762/23511/3190/1911/23279/79902/7341/84733/57332/7329/6396/55746/6015 23 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-203927 MicroRNA (miRNA) biogenesis 15/2027 24/10654 3.3743675745691157e-6 1.0912671491155785e-5 5.3804409083744e-6 5434/5440/5430/5436/5441/192670/5438/5431/5435/5433/5437/5439/192669/26523/5432 15 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-933542 TRAF6 mediated NF-kB activation 15/2027 24/10654 3.3743675745691157e-6 1.0912671491155785e-5 5.3804409083744e-6 1147/351/7186/4790/57506/4214/7706/8517/5970/4792/4793/3146/7189/3551/4791 15 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 15/2027 24/10654 3.3743675745691157e-6 1.0912671491155785e-5 5.3804409083744e-6 596/2309/207/5594/1027/1950/10000/595/2002/208/7514/1385/2353/1956/5595 15 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 21/2027 41/10654 3.4877329617986476e-6 1.1251580783394653e-5 5.547538527107638e-6 53981/5903/29894/348995/79023/57122/10762/23511/81608/4686/8189/23279/79902/10898/10189/51692/1977/6396/55746/22916/55339 21 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5620912 Anchoring of the basal body to the plasma membrane 38/2027 98/10654 3.905801459130338e-6 1.2569405185877781e-5 6.197285596917334e-6 22995/7531/10142/80776/11190/54801/1454/10382/85302/5048/1781/22832/8655/9738/983/1639/5566/79959/84131/7846/7283/3320/22919/11064/4867/10733/1069/4751/5577/5518/54820/5347/23322/23332/22897/9793/8481/1778 38 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9009391 Extra-nuclear estrogen signaling 32/2027 77/10654 4.003350097292998e-6 1.2851830507935712e-5 6.336534062116057e-6 5295/596/4893/6464/5290/54331/4316/2309/207/5594/1027/3315/4318/2100/1950/4314/6714/2099/10000/3320/4846/595/2002/208/7514/1385/2353/1956/3845/3265/3480/5595 32 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1538133 G0 and Early G1 16/2027 27/10654 4.280916310919562e-6 1.3676017314446193e-5 6.742895457076529e-6 1017/9134/7027/7153/898/4149/286826/993/890/983/5111/4609/5928/990/3065/8900 16 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 16/2027 27/10654 4.280916310919562e-6 1.3676017314446193e-5 6.742895457076529e-6 7186/1612/842/8737/356/355/841/7099/8797/836/929/8837/8772/8717/8743/8795 16 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8848021 Signaling by PTK6 25/2027 54/10654 4.490193405642127e-6 1.427511850268308e-5 7.038279455766301e-6 120892/1017/1019/4893/207/9021/1027/898/3091/2064/7316/1950/6774/6421/2908/595/6233/1398/7311/2034/387/1956/3845/3265/7314 25 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 25/2027 54/10654 4.490193405642127e-6 1.427511850268308e-5 7.038279455766301e-6 120892/1017/1019/4893/207/9021/1027/898/3091/2064/7316/1950/6774/6421/2908/595/6233/1398/7311/2034/387/1956/3845/3265/7314 25 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-4090294 SUMOylation of intracellular receptors 17/2027 30/10654 4.9920329788517355e-6 1.5832220534377605e-5 7.806001225511867e-6 6095/5468/6613/2516/5465/9759/2099/7341/10401/2908/7329/367/6612/9063/7421/10062/8554 17 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 12/2027 17/10654 5.201497816973619e-6 1.6456787069123766e-5 8.11394079248897e-6 1147/11035/4790/8737/8517/4615/5970/4792/4793/1660/3551/4791 12 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-198753 ERK/MAPK targets 14/2027 22/10654 5.335188130480363e-6 1.6839187536828646e-5 8.302481528961091e-6 5594/5528/4205/5519/5598/1432/4208/2002/6196/5518/5600/5595/5515/5516 14 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-202433 Generation of second messenger molecules 18/2027 33/10654 5.478062162017886e-6 1.724867054851195e-5 8.504375185260633e-6 3120/9402/4690/3117/3119/3123/919/3115/3122/3113/915/917/916/7535/3702/3932/3127/5062 18 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 21/2027 42/10654 5.730730631415622e-6 1.7958112933290483e-5 8.854162387440292e-6 53981/5903/29894/348995/79023/57122/10762/23511/81608/4686/8189/23279/79902/10898/10189/51692/1977/6396/55746/22916/55339 21 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 21/2027 42/10654 5.730730631415622e-6 1.7958112933290483e-5 8.854162387440292e-6 9070/8945/1499/207/8085/5929/6657/7534/7316/6934/324/3065/208/6233/7514/90780/7311/331/25776/7314/4221 21 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-73933 Resolution of Abasic Sites (AP sites) 20/2027 39/10654 5.816988780320701e-6 1.818501492514543e-5 8.9660353380883e-6 11284/6118/2237/4350/328/5982/3978/5111/6119/5427/5985/142/5984/3980/5983/6117/5981/10038/5424/7374 20 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1643713 Signaling by EGFR in Cancer 15/2027 25/10654 6.95156445518501e-6 2.1680294844793155e-5 1.0689366520662037e-5 5295/4893/6464/5290/7316/1950/3320/6233/2885/7311/1956/3845/3265/11140/7314 15 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5637810 Constitutive Signaling by EGFRvIII 11/2027 15/10654 7.375340482824774e-6 2.289319634503293e-5 1.1287381851280917e-5 5295/4893/6464/5290/1950/3320/2885/1956/3845/3265/11140 11 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5637812 Signaling by EGFRvIII in Cancer 11/2027 15/10654 7.375340482824774e-6 2.289319634503293e-5 1.1287381851280917e-5 5295/4893/6464/5290/1950/3320/2885/1956/3845/3265/11140 11 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 34/2027 86/10654 7.577973016588846e-6 2.3466694742408383e-5 1.157014251539757e-5 5295/25/5290/51517/5291/4690/4771/5594/2268/2209/919/3055/6850/10768/6714/4067/917/3320/2534/998/695/2885/7525/1398/7410/10096/3326/10097/7409/60/5581/10095/10109/5595 34 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-167044 Signalling to RAS 13/2027 20/10654 8.351160264003462e-6 2.5739608982714895e-5 1.269079209874507e-5 4893/6464/9261/6714/1432/4914/4803/5603/2885/3845/5600/3265/6300 13 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-3232118 SUMOylation of transcription factors 13/2027 20/10654 8.351160264003462e-6 2.5739608982714895e-5 1.269079209874507e-5 7020/1029/9112/6613/7341/10401/7157/7329/7158/6612/9063/4193/8554 13 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8856828 Clathrin-mediated endocytosis 50/2027 146/10654 8.693876236757238e-6 2.6733160418881154e-5 1.3180657920881799e-5 9318/1173/6857/23048/5868/1856/9892/4738/2060/409/1080/29978/112574/338/7316/1950/273/64708/10980/2017/915/917/4074/10920/408/26119/9829/10987/29979/6233/2885/2873/10096/10097/7311/3575/1759/1213/1956/60/8533/51429/3312/10109/6457/50813/7314/50618/51138/11252 50 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-75893 TNF signaling 21/2027 43/10654 9.203368784100456e-6 2.8233699097018453e-5 1.3920491397495771e-5 7124/1147/81858/7186/8737/9530/330/841/8517/7316/7132/329/10616/6233/7311/8772/331/8717/1540/3551/7314 21 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5654741 Signaling by FGFR3 20/2027 40/10654 9.562855637562077e-6 2.9268133921023327e-5 1.443051458005319e-5 5295/4893/6464/5290/5594/7316/673/6714/2261/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 20 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 36/2027 94/10654 9.674777728116084e-6 2.954182129538702e-5 1.4565454841594595e-5 10844/22995/7531/10142/11190/54801/1454/10382/5048/1781/8655/9738/983/1639/5566/79959/84131/7846/7283/3320/22919/10426/11064/10733/1069/4751/5577/5518/54820/5347/84790/23332/22897/9793/8481/1778 36 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 10/2027 13/10654 9.909999035751491e-6 3.0119973921161357e-5 1.485051025094339e-5 207/10193/9101/2064/7316/10000/208/6233/7311/7314 10 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-68884 Mitotic Telophase/Cytokinesis 10/2027 13/10654 9.909999035751491e-6 3.0119973921161357e-5 1.485051025094339e-5 10274/23244/10735/23047/5885/10112/8243/9126/5347/9493 10 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-168254 Influenza Infection 52/2027 155/10654 1.1285180104676962e-5 3.4220419116491574e-5 1.6872215301753575e-5 3303/6138/2963/3837/3838/5434/5440/5903/6128/6129/5430/5436/6152/8106/348995/6141/9636/6202/79023/57122/5441/6232/5438/10762/5431/23511/5435/5433/5611/23279/79902/2962/10898/3840/6204/5437/3320/5439/6207/3836/6233/7514/7311/1213/5610/7040/6396/3304/9045/5432/55746/6137 52 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2468052 Establishment of Sister Chromatid Cohesion 9/2027 11/10654 1.2186142994371364e-5 3.678254195772322e-5 1.813545781376501e-5 10274/23244/10735/23047/5885/8243/9126/113130/157570 9 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9614399 Regulation of localization of FOXO transcription factors 9/2027 11/10654 1.2186142994371364e-5 3.678254195772322e-5 1.813545781376501e-5 2308/2309/207/4303/2810/7534/10000/208/7529 9 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5654736 Signaling by FGFR1 23/2027 50/10654 1.2301014897741782e-5 3.704411137783248e-5 1.8264423375449536e-5 5295/4893/6464/5290/5594/2260/7316/673/6714/6233/2885/7311/5518/53834/3845/3265/200734/5781/7314/161742/5595/5515/5516 23 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 12/2027 18/10654 1.2894093896531125e-5 3.874129356097338e-5 1.9101210999317457e-5 3665/29110/7099/7316/929/3661/6233/10010/7311/7187/5781/7314 12 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6783783 Interleukin-10 signaling 22/2027 47/10654 1.3426852092327874e-5 4.024990136353082e-5 1.984502291944639e-5 7124/1437/6351/3553/2919/5743/941/3383/3576/2920/6352/6774/7133/3606/7132/3552/942/6347/3569/1234/3586/5724 22 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-73886 Chromosome Maintenance 40/2027 110/10654 1.369944319651624e-5 4.0973505505753585e-5 2.020179250894974e-5 7014/6118/55839/25913/79682/2237/7015/1763/1058/401541/79019/80152/5982/79172/5931/7013/23421/55355/64105/3978/5557/5422/5111/55166/6119/5928/2491/5427/5985/91687/1060/5984/8607/11339/5983/6117/5981/64946/54386/5424 40 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-4420097 VEGFA-VEGFR2 Pathway 37/2027 99/10654 1.4018725722968376e-5 4.183315198694881e-5 2.0625637128290796e-5 5295/4893/5290/653361/5291/1499/4690/5567/207/7422/5568/3315/9261/10768/6714/5566/1432/10000/3320/2534/4846/3728/5603/998/208/1398/7410/2475/7409/8440/387/60/3845/5600/3265/6300/5062 37 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-156711 Polo-like kinase mediated events 11/2027 16/10654 1.9526803226331644e-5 5.7875152677592436e-5 2.853506946464052e-5 2305/1063/9133/286826/891/993/5928/2033/995/5347/7465 11 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-205043 NRIF signals cell death from the nucleus 11/2027 16/10654 1.9526803226331644e-5 5.7875152677592436e-5 2.853506946464052e-5 8878/23421/7316/5664/4803/7189/6233/7311/5599/5663/7314 11 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 11/2027 16/10654 1.9526803226331644e-5 5.7875152677592436e-5 2.853506946464052e-5 5295/6464/5290/2205/5291/2206/6850/4067/2534/2885/2207 11 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1236394 Signaling by ERBB4 25/2027 58/10654 2.1122963173450104e-5 6.246497893409907e-5 3.079806152601189e-5 5295/4893/6464/5290/51741/6776/7316/1950/9611/11059/4734/10413/6714/2099/5664/83737/1742/6233/2885/7311/1956/3845/3265/5663/7314 25 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5260271 Diseases of Immune System 14/2027 24/10654 2.2264383888998785e-5 6.554514808577445e-5 3.2316724313746175e-5 1147/4790/7099/8517/4615/5970/4792/929/114609/695/81622/7187/3551/4791 14 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5602358 Diseases associated with the TLR signaling cascade 14/2027 24/10654 2.2264383888998785e-5 6.554514808577445e-5 3.2316724313746175e-5 1147/4790/7099/8517/4615/5970/4792/929/114609/695/81622/7187/3551/4791 14 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 19/2027 39/10654 2.5618969203436906e-5 7.525213996445785e-5 3.710271060900435e-5 26224/9134/8841/8237/898/10517/6774/26272/11328/26270/3801/55294/26190/10238/7157/6468/54461/26234/84261 19 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2424491 DAP12 signaling 16/2027 30/10654 2.6685911923372427e-5 7.80876766653867e-5 3.850075852744845e-5 5295/9402/4893/6464/5290/5291/567/6850/2534/695/2885/7410/3133/3932/3845/3265 16 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 18/2027 36/10654 2.6703249674606722e-5 7.80876766653867e-5 3.850075852744845e-5 4893/5604/8844/5594/409/673/6714/2335/408/1445/5894/60/4140/3845/3265/369/7529/5595 18 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1839126 FGFR2 mutant receptor activation 17/2027 33/10654 2.71367259504832e-5 7.917893593996543e-5 3.903879873578285e-5 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2263/2962/5437/5439/5432/22916 17 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-389359 CD28 dependent Vav1 pathway 9/2027 12/10654 4.046169631067434e-5 1.1701807765620134e-4 5.769520804791264e-5 941/2534/998/942/2885/7409/3932/5062/940 9 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 9/2027 12/10654 4.046169631067434e-5 1.1701807765620134e-4 5.769520804791264e-5 3665/29110/7316/3661/6233/10010/7311/7187/7314 9 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 9/2027 12/10654 4.046169631067434e-5 1.1701807765620134e-4 5.769520804791264e-5 1147/8737/57506/841/7706/8517/843/8772/3551 9 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9634600 Regulation of glycolysis by fructose 2,6-bisphosphate metabolism 9/2027 12/10654 4.046169631067434e-5 1.1701807765620134e-4 5.769520804791264e-5 5567/5568/5528/5566/5519/5518/5207/5515/5516 9 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-4655427 SUMOylation of DNA methylation proteins 11/2027 17/10654 4.578986314348819e-5 1.3213646221406591e-4 6.514925583168362e-5 1912/8535/1786/6045/80012/1911/7341/84733/57332/7329/6015 11 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6802957 Oncogenic MAPK signaling 28/2027 71/10654 4.9811845085716224e-5 1.4303896927304375e-4 7.052468521499331e-5 4000/815/8805/4893/5604/10018/10142/8844/5594/409/10533/673/6714/2335/408/1445/816/5894/60/4140/9444/3845/3265/369/4763/5245/7529/5595 28 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 21/2027 47/10654 5.01126625023611e-5 1.4303896927304375e-4 7.052468521499331e-5 815/4893/5604/8844/5594/409/673/6714/2335/408/1445/816/5894/60/4140/3845/3265/369/5245/7529/5595 21 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6802949 Signaling by RAS mutants 21/2027 47/10654 5.01126625023611e-5 1.4303896927304375e-4 7.052468521499331e-5 815/4893/5604/8844/5594/409/673/6714/2335/408/1445/816/5894/60/4140/3845/3265/369/5245/7529/5595 21 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 21/2027 47/10654 5.01126625023611e-5 1.4303896927304375e-4 7.052468521499331e-5 815/4893/5604/8844/5594/409/673/6714/2335/408/1445/816/5894/60/4140/3845/3265/369/5245/7529/5595 21 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9649948 Signaling downstream of RAS mutants 21/2027 47/10654 5.01126625023611e-5 1.4303896927304375e-4 7.052468521499331e-5 815/4893/5604/8844/5594/409/673/6714/2335/408/1445/816/5894/60/4140/3845/3265/369/5245/7529/5595 21 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-111367 SLBP independent Processing of Histone Pre-mRNAs 8/2027 10/10654 5.283678650989403e-5 1.5016168979976378e-4 7.40365087800976e-5 6635/84967/6637/4686/6636/6634/22916/6628 8 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8877330 RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) 8/2027 10/10654 5.283678650989403e-5 1.5016168979976378e-4 7.40365087800976e-5 4773/865/3558/50943/3458/861/3559/1493 8 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5628897 TP53 Regulates Metabolic Genes 32/2027 86/10654 5.780781130917031e-5 1.6393446274069246e-4 8.082710913979707e-5 9377/5563/1329/7531/207/57690/27327/7533/2810/192670/7534/7001/84987/54205/6341/5571/10000/5728/192669/7157/8626/23112/208/2475/5562/4513/4343/1327/26523/5052/57521/7529 32 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5654743 Signaling by FGFR4 19/2027 41/10654 6.156172929826474e-5 1.742037727772017e-4 8.589034373510168e-5 5295/4893/6464/5290/5594/7316/673/6714/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 19 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-3232142 SUMOylation of ubiquitinylation proteins 18/2027 38/10654 6.694935764179073e-5 1.8904194964230374e-4 9.320623644527742e-5 5903/348995/79023/57122/10762/23511/23279/79902/7341/7428/7329/5987/5371/9063/6396/55746/4193/8554 18 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5358508 Mismatch Repair 10/2027 15/10654 7.147023990184818e-5 2.005137286135185e-4 9.886234264425694e-5 6118/4436/9156/2956/3978/5111/6119/6117/5424/4437 10 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69183 Processive synthesis on the lagging strand 10/2027 15/10654 7.147023990184818e-5 2.005137286135185e-4 9.886234264425694e-5 6118/2237/1763/3978/5557/5422/5111/6119/6117/5424 10 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 10/2027 15/10654 7.147023990184818e-5 2.005137286135185e-4 9.886234264425694e-5 3665/4615/7316/7335/3654/7189/6233/7311/7334/7314 10 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 15/2027 29/10654 7.621523713189657e-5 2.1337016280208998e-4 1.0520114652927034e-4 2308/2309/4303/4287/114907/84676/4089/4088/2908/3630/3066/3065/6648/4087/25942 15 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-168253 Host Interactions with Influenza Factors 19/2027 42/10654 9.251474995885331e-5 2.5845078020420085e-4 1.274279310743444e-4 3837/3838/5903/8106/348995/9636/79023/57122/10762/23511/23279/79902/10898/3840/3836/5610/7040/6396/55746 19 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 11/2027 18/10654 9.748321481727732e-5 2.7175257124221894e-4 1.3398631604117901e-4 4893/5594/4314/5598/2885/1385/6196/1956/3845/3265/5595 11 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-194138 Signaling by VEGF 37/2027 107/10654 9.822002786509043e-5 2.7322647581962654e-4 1.3471301770078196e-4 5295/4893/5290/653361/5291/1499/4690/5567/207/7422/5568/3315/9261/10768/6714/5566/1432/10000/3320/2534/4846/3728/5603/998/208/1398/7410/2475/7409/8440/387/60/3845/5600/3265/6300/5062 37 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-438064 Post NMDA receptor activation events 30/2027 81/10654 1.0753008710702923e-4 2.98492609664967e-4 1.4717036512923776e-4 5923/5563/815/3838/4893/28964/5575/5567/10382/5594/5568/5573/6714/5566/5571/7846/5576/4137/816/1742/5577/1385/6196/5562/1740/84790/3845/3265/2891/5595 30 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 9/2027 13/10654 1.0920301517925059e-4 3.018601240639074e-4 1.4883070212795373e-4 7027/5925/5557/5422/5519/28227/5518/5515/5516 9 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-171007 p38MAPK events 9/2027 13/10654 1.0920301517925059e-4 3.018601240639074e-4 1.4883070212795373e-4 4893/9261/6714/1432/5603/3845/5600/3265/6300 9 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6802952 Signaling by BRAF and RAF fusions 26/2027 67/10654 1.2555659665041237e-4 3.463357382394778e-4 1.707591927023521e-4 4000/815/8805/4893/5604/10018/10142/8844/5594/409/10533/673/6714/2335/408/1445/816/5894/60/4140/9444/3845/3265/369/7529/5595 26 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-168276 NS1 Mediated Effects on Host Pathways 18/2027 40/10654 1.5329043051145243e-4 4.2106764699066326e-4 2.0760540577965922e-4 3837/3838/5903/8106/348995/9636/79023/57122/10762/23511/23279/79902/10898/3840/3836/5610/6396/55746 18 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5674135 MAP2K and MAPK activation 18/2027 40/10654 1.5329043051145243e-4 4.2106764699066326e-4 2.0760540577965922e-4 4893/5604/8844/5594/409/673/6714/2335/408/1445/5894/60/4140/3845/3265/369/7529/5595 18 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1433559 Regulation of KIT signaling 10/2027 16/10654 1.58042634361042e-4 4.323124560751003e-4 2.1314960555272113e-4 5777/3815/9306/6714/8651/4067/2534/2885/7525/3932 10 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9614657 FOXO-mediated transcription of cell death genes 10/2027 16/10654 1.58042634361042e-4 4.323124560751003e-4 2.1314960555272113e-4 2308/2309/10018/356/4303/1649/4800/1387/2033/604 10 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 8/2027 11/10654 1.6123850255128736e-4 4.3518521177981036e-4 2.1456600412441047e-4 64344/7422/3091/1387/2033/2056/2034/405 8 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-174414 Processive synthesis on the C-strand of the telomere 8/2027 11/10654 1.6123850255128736e-4 4.3518521177981036e-4 2.1456600412441047e-4 6118/2237/1763/3978/5111/6119/6117/5424 8 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2514853 Condensation of Prometaphase Chromosomes 8/2027 11/10654 1.6123850255128736e-4 4.3518521177981036e-4 2.1456600412441047e-4 64151/1460/9133/891/1457/983/9918/10592 8 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-4755510 SUMOylation of immune response proteins 8/2027 11/10654 1.6123850255128736e-4 4.3518521177981036e-4 2.1456600412441047e-4 8517/5970/4792/7341/10401/7329/6612/4791 8 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-68689 CDC6 association with the ORC:origin complex 8/2027 11/10654 1.6123850255128736e-4 4.3518521177981036e-4 2.1456600412441047e-4 5000/23594/84515/4998/990/23595/5001/4999 8 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-77588 SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs 8/2027 11/10654 1.6123850255128736e-4 4.3518521177981036e-4 2.1456600412441047e-4 6635/84967/6637/4686/6636/6634/22916/6628 8 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-212165 Epigenetic regulation of gene expression 47/2027 149/10654 1.61412946029526e-4 4.3518521177981036e-4 2.1456600412441047e-4 23451/5434/5440/902/2146/9112/9219/1786/30834/404672/5931/5441/51082/8932/5435/200424/80312/4331/1108/2966/8850/5928/2932/29947/5437/57459/2965/54815/2033/23512/2068/3066/3065/2071/1107/54790/2968/57504/2967/6908/23411/60/25942/8726/53615/1022/9188 47 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 36/2027 106/10654 1.8333412345914553e-4 4.93273983815283e-4 2.4320639760003128e-4 9318/1173/6857/1856/9892/4738/2060/409/1080/29978/338/7316/1950/64708/10980/915/917/4074/10920/408/26119/10987/29979/6233/2885/2873/7311/3575/1213/1956/8533/6457/50813/7314/50618/51138 36 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6804760 Regulation of TP53 Activity through Methylation 11/2027 19/10654 1.917472760915492e-4 5.148551605484747e-4 2.538468944059903e-4 11200/472/7316/4194/2033/7157/6233/7311/26013/7314/4193 11 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-389357 CD28 dependent PI3K/Akt signaling 12/2027 22/10654 2.1000239393159078e-4 5.615746298007713e-4 2.768817070809912e-4 5295/5290/207/941/9020/10000/2534/942/208/2475/3932/940 12 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9613829 Chaperone Mediated Autophagy 12/2027 22/10654 2.1000239393159078e-4 5.615746298007713e-4 2.768817070809912e-4 1915/1080/10013/7316/3320/6233/3326/7311/7431/3312/11315/7314 12 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9006115 Signaling by NTRK2 (TRKB) 13/2027 25/10654 2.1545169906789276e-4 5.738094946777753e-4 2.8291404916569674e-4 5295/627/4893/6464/5290/6714/2534/2885/8851/3845/3265/1020/5781 13 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9006335 Signaling by Erythropoietin 13/2027 25/10654 2.1545169906789276e-4 5.738094946777753e-4 2.8291404916569674e-4 5295/4893/6464/5290/5291/6776/4067/2885/2056/7409/3845/6777/3265 13 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-174411 Polymerase switching on the C-strand of the telomere 9/2027 14/10654 2.54035889981405e-4 6.657667136638418e-4 3.2825311973645147e-4 5982/5557/5422/5111/5985/5984/5983/5981/5424 9 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 9/2027 14/10654 2.54035889981405e-4 6.657667136638418e-4 3.2825311973645147e-4 6118/4436/9156/2956/3978/5111/6119/6117/5424 9 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 9/2027 14/10654 2.54035889981405e-4 6.657667136638418e-4 3.2825311973645147e-4 6118/4436/9156/3978/5111/6119/6117/5424/4437 9 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69091 Polymerase switching 9/2027 14/10654 2.54035889981405e-4 6.657667136638418e-4 3.2825311973645147e-4 5982/5557/5422/5111/5985/5984/5983/5981/5424 9 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69109 Leading Strand Synthesis 9/2027 14/10654 2.54035889981405e-4 6.657667136638418e-4 3.2825311973645147e-4 5982/5557/5422/5111/5985/5984/5983/5981/5424 9 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-69166 Removal of the Flap Intermediate 9/2027 14/10654 2.54035889981405e-4 6.657667136638418e-4 3.2825311973645147e-4 6118/2237/1763/5557/5422/5111/6119/6117/5424 9 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-877312 Regulation of IFNG signaling 9/2027 14/10654 2.54035889981405e-4 6.657667136638418e-4 3.2825311973645147e-4 5777/9021/6772/8651/7341/5771/3458/5781/8554 9 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-918233 TRAF3-dependent IRF activation pathway 9/2027 14/10654 2.54035889981405e-4 6.657667136638418e-4 3.2825311973645147e-4 3665/29110/57506/7706/1387/2033/3661/7187/3456 9 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-168255 Influenza Life Cycle 45/2027 144/10654 2.787819585400263e-4 7.291647640698297e-4 3.5951122772513353e-4 3303/6138/2963/3837/5434/5440/5903/6128/6129/5430/5436/6152/348995/6141/6202/79023/57122/5441/6232/5438/10762/5431/23511/5435/5433/5611/23279/79902/2962/6204/5437/3320/5439/6207/3836/6233/7514/7311/1213/6396/3304/9045/5432/55746/6137 45 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9034015 Signaling by NTRK3 (TRKC) 10/2027 17/10654 3.184037361004048e-4 8.311413628227266e-4 4.0979030595741125e-4 5295/4893/6464/5290/3667/6714/2885/3845/3265/25920 10 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5654732 Negative regulation of FGFR3 signaling 14/2027 29/10654 3.3764051300897856e-4 8.796071301206128e-4 4.3368612259925195e-4 5594/7316/673/6714/2261/6233/2885/7311/5518/5781/7314/5595/5515/5516 14 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8876384 Listeria monocytogenes entry into host cells 11/2027 20/10654 3.5302583157748176e-4 9.178671621014526e-4 4.5255004985961705e-4 1499/2060/7316/4233/6714/999/6233/2885/7311/6457/7314 11 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-112409 RAF-independent MAPK1/3 activation 12/2027 23/10654 3.63375388995202e-4 9.429088651199609e-4 4.6489674273361605e-4 1844/5604/5594/983/80824/1847/1843/5781/3569/8682/11221/5595 12 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-191859 snRNP Assembly 21/2027 53/10654 3.930998476493249e-4 0.0010160238188259125 5.009457237967981e-4 6635/5903/6633/6632/6637/348995/79023/57122/10762/23511/4686/23279/79902/51808/1207/6636/6634/6396/55746/22916/6628 21 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-194441 Metabolism of non-coding RNA 21/2027 53/10654 3.930998476493249e-4 0.0010160238188259125 5.009457237967981e-4 6635/5903/6633/6632/6637/348995/79023/57122/10762/23511/4686/23279/79902/51808/1207/6636/6634/6396/55746/22916/6628 21 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-210990 PECAM1 interactions 8/2027 12/10654 4.0279211503251364e-4 0.0010349629100541886 5.102835528787639e-4 5777/5175/6714/4067/2534/7525/3932/5781 8 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5689877 Josephin domain DUBs 8/2027 12/10654 4.0279211503251364e-4 0.0010349629100541886 5.102835528787639e-4 4287/7316/7415/6233/7311/5887/5886/7314 8 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9020558 Interleukin-2 signaling 8/2027 12/10654 4.0279211503251364e-4 0.0010349629100541886 5.102835528787639e-4 6464/6776/3560/6850/3558/3932/6777/3559 8 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 23/2027 61/10654 4.933730662523408e-4 0.0012652321015416475 6.238166853313932e-4 25/51517/4690/4771/5594/2209/919/6850/917/3320/998/695/2885/1398/7410/10096/3326/10097/7409/60/10095/10109/5595 23 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 29/2027 84/10654 5.519897737119368e-4 0.0014127925397344502 6.965706593471656e-4 6517/7124/1019/8841/4790/5468/29079/1051/7471/688/5465/9611/5469/1050/5970/9612/1387/6604/9439/2033/10498/4023/9477/23054/7040/51586/8202/8648/1959 29 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1368082 RORA activates gene expression 10/2027 18/10654 5.945543877043128e-4 0.0015128874245266721 7.459219674380914e-4 6095/1374/5465/5469/1387/6604/2033/10498/23054/8648 10 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 10/2027 18/10654 5.945543877043128e-4 0.0015128874245266721 7.459219674380914e-4 5295/8805/11052/5290/6776/6774/6772/11064/2885/6777 10 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 10/2027 18/10654 5.945543877043128e-4 0.0015128874245266721 7.459219674380914e-4 7027/2810/891/983/6790/5111/2033/995/7157/10498 10 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-174437 Removal of the Flap Intermediate from the C-strand 7/2027 10/10654 6.24038700145832e-4 0.0015666592988364768 7.724339349696824e-4 6118/2237/1763/5111/6119/6117/5424 7 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2465910 MASTL Facilitates Mitotic Progression 7/2027 10/10654 6.24038700145832e-4 0.0015666592988364768 7.724339349696824e-4 891/983/5519/5518/55844/5515/5516 7 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2470946 Cohesin Loading onto Chromatin 7/2027 10/10654 6.24038700145832e-4 0.0015666592988364768 7.724339349696824e-4 10274/23244/10735/23047/5885/8243/9126 7 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5685939 HDR through MMEJ (alt-NHEJ) 7/2027 10/10654 6.24038700145832e-4 0.0015666592988364768 7.724339349696824e-4 2237/10111/4683/142/5932/3980/10038 7 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-74749 Signal attenuation 7/2027 10/10654 6.24038700145832e-4 0.0015666592988364768 7.724339349696824e-4 3643/6464/3667/5594/3630/2885/5595 7 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8853334 Signaling by FGFR3 fusions in cancer 7/2027 10/10654 6.24038700145832e-4 0.0015666592988364768 7.724339349696824e-4 5295/4893/5290/2261/2885/3845/3265 7 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 7/2027 10/10654 6.24038700145832e-4 0.0015666592988364768 7.724339349696824e-4 2308/2309/4303/8850/1387/2033/23411 7 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-451927 Interleukin-2 family signaling 18/2027 44/10654 6.414546589590601e-4 0.0016073090977352022 7.924761254717196e-4 5295/5777/6464/5290/1437/5291/6775/6776/3560/6774/6850/6772/3558/2885/3932/6777/3600/3559 18 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 22/2027 59/10654 7.740544577364373e-4 0.0019358733390627471 9.544731659306445e-4 7319/7321/56852/9646/7320/79577/7336/5591/7323/7316/56254/5111/7415/7322/118424/7324/6233/7311/7334/3105/6596/7314 22 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-383280 Nuclear Receptor transcription pathway 20/2027 52/10654 8.412659646059037e-4 0.0020999661816113145 0.0010353783634833517 3174/6095/7182/5468/3172/2516/6097/5465/2100/9611/5469/2063/9612/2099/7101/2908/2103/367/7421/10062 20 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-111461 Cytochrome c-mediated apoptotic response 8/2027 13/10654 8.725346747977329e-4 0.002162208702510428 0.0010660667431305673 842/5594/54205/56616/836/840/331/5595 8 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-202670 ERKs are inactivated 8/2027 13/10654 8.725346747977329e-4 0.002162208702510428 0.0010660667431305673 5594/5528/5519/5598/5518/5595/5515/5516 8 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5357786 TNFR1-induced proapoptotic signaling 8/2027 13/10654 8.725346747977329e-4 0.002162208702510428 0.0010660667431305673 7124/7186/8737/841/7132/8772/8717/1540 8 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5655302 Signaling by FGFR1 in disease 16/2027 38/10654 8.727879758800662e-4 0.002162208702510428 0.0010660667431305673 5295/8805/4893/11052/5290/9530/2260/6776/6774/6772/11064/2885/11160/3845/6777/3265 16 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-177929 Signaling by EGFR 19/2027 49/10654 0.0010028733998761624 0.0024625380325212073 0.0012141426945128013 5295/4893/6464/5290/2060/7316/1950/6714/1445/998/6233/2885/7311/1956/3845/3265/5781/6457/7314 19 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 19/2027 49/10654 0.0010028733998761624 0.0024625380325212073 0.0012141426945128013 1017/9134/7027/7832/1027/898/2810/891/890/983/1026/6790/5111/2033/995/7157/8900/10498/1263 19 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9012852 Signaling by NOTCH3 19/2027 49/10654 0.0010028733998761624 0.0024625380325212073 0.0012141426945128013 142678/4904/3280/10460/7316/1950/6772/5664/22938/8850/1387/2033/6233/7311/1956/9787/4851/5663/7314 19 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 9/2027 16/10654 0.001003395161766067 0.0024625380325212073 0.0012141426945128013 57154/7316/7046/6233/7048/7311/387/7040/7314 9 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-399956 CRMPs in Sema3A signaling 9/2027 16/10654 0.001003395161766067 0.0024625380325212073 0.0012141426945128013 1400/1809/2932/2534/1808/10570/56896/8851/1020 9 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 10/2027 19/10654 0.0010421178450518269 0.002552799870434792 0.0012586458654887539 7027/7153/4149/286826/993/5111/4609/5928/990/3065 10 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 13/2027 29/10654 0.0013157786293802565 0.0032171645072183925 0.0015862076978709358 5434/5440/5430/5436/5441/5438/5431/5435/5433/5437/3320/5439/5432 13 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-1236977 Endosomal/Vacuolar pathway 7/2027 11/10654 0.0014339390459362851 0.003499557560063833 0.0017254402528875277 3135/3107/567/3106/3133/3134/3105 7 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-193704 p75 NTR receptor-mediated signalling 31/2027 97/10654 0.0015678032304626997 0.0038191570345037563 0.0018830172575618797 9181/8841/4790/10018/7531/8767/8878/1894/23421/4615/7316/5970/4792/5664/836/396/4803/3066/3065/3654/7189/6233/7410/7409/7311/8997/387/5599/3551/5663/7314 31 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-442755 Activation of NMDA receptors and postsynaptic events 30/2027 93/10654 0.001571060625288481 0.0038200048166736585 0.0018834352525388225 5923/5563/815/3838/4893/28964/5575/5567/10382/5594/5568/5573/6714/5566/5571/7846/5576/4137/816/1742/5577/1385/6196/5562/1740/84790/3845/3265/2891/5595 30 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5654726 Negative regulation of FGFR1 signaling 14/2027 33/10654 0.001663735511608433 0.004037864559596807 0.001990849965247955 5594/2260/7316/673/6714/6233/2885/7311/5518/5781/7314/5595/5515/5516 14 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-162594 Early Phase of HIV Life Cycle 8/2027 14/10654 0.001697199721219506 0.004081361234361192 0.0020122957943898134 2237/3159/7520/3978/3981/3836/2547/1234 8 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-169893 Prolonged ERK activation events 8/2027 14/10654 0.001697199721219506 0.004081361234361192 0.0020122957943898134 5604/5594/673/4914/4803/1398/7529/5595 8 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase 8/2027 14/10654 0.001697199721219506 0.004081361234361192 0.0020122957943898134 5575/5567/5568/5573/5566/5576/5577/1385 8 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 8/2027 14/10654 0.001697199721219506 0.004081361234361192 0.0020122957943898134 1017/9134/1027/898/890/1026/7157/8900 8 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9027284 Erythropoietin activates RAS 8/2027 14/10654 0.001697199721219506 0.004081361234361192 0.0020122957943898134 4893/6464/4067/2885/2056/7409/3845/3265 8 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5617472 Activation of anterior HOX genes in hindbrain development during early embryogenesis 37/2027 122/10654 0.0017100943371127315 0.00409736106684127 0.0020201844358899925 9070/3725/5434/5440/8841/11091/2146/5430/84962/8085/5436/5929/5931/5441/3213/5438/5431/7403/5435/5433/9611/9935/5928/22976/1387/5437/2033/23512/5439/58508/23054/9063/8726/8202/5432/1959/7528 37 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-5619507 Activation of HOX genes during differentiation 37/2027 122/10654 0.0017100943371127315 0.00409736106684127 0.0020201844358899925 9070/3725/5434/5440/8841/11091/2146/5430/84962/8085/5436/5929/5931/5441/3213/5438/5431/7403/5435/5433/9611/9935/5928/22976/1387/5437/2033/23512/5439/58508/23054/9063/8726/8202/5432/1959/7528 37 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 9/2027 17/10654 0.001774010515639936 0.004242761032851068 0.0020918731993453377 2308/2309/4303/1027/1026/901/4089/4088/4087 9 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 15/2027 37/10654 0.001986985902074656 0.004743477253498224 0.0023387489565089253 8841/347/57690/27327/192670/9611/9612/2033/192669/23028/23112/4343/26523/8648/10062 15 Human_immunodeficiency_virus_type_2_subtype_A R-HSA-2132295 MHC class II antigen presentation 37/2027 123/10654 0.002006600696864193 0.004781609283090173 0.0023575497727986983 3120/1173/164/1783/3117/3119/10484/10382/29127/3123/3832/1780/3115/1781/3122/8655/1639/1510/3113/3796/10112/1062/10437/7846/56992/51143/11004/1759/1213/84790/84643/3127/9493/6396/81930/140735/1778 37 Human_metapneumovirus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 253/1124 309/10654 9.732326551450193e-200 1.204862027069534e-196 6.945807791456032e-197 8454/9354/57154/197131/23352/26224/8945/10293/51088/140460/79754/6737/8065/64410/127544/114088/11065/285231/221687/9666/84937/57531/142678/55070/84708/246184/146330/55819/51320/93611/7319/54850/142686/8916/79791/26046/151636/7321/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/8697/7320/26235/10477/9817/10193/148581/9039/223082/92912/154881/140739/25897/6500/6478/150726/390594/10533/81559/144699/140462/26259/57674/51130/53339/154214/7336/200845/79876/26263/64750/51619/6477/9690/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/9604/9978/22888/23304/7317/80196/114907/140456/64718/54926/4008/7335/84861/11059/55236/84085/55958/54620/4734/84078/7337/26272/84676/27252/51444/7704/8651/3093/26118/222235/51433/25831/7322/5715/64219/10489/23327/9867/26249/140458/55905/55336/26270/143279/51465/63893/89122/6502/23291/118424/10616/27246/89910/55521/25898/9903/201456/55294/26190/55008/7328/79654/10422/84727/135892/7428/22954/8453/401036/83737/51529/9040/90933/140461/7324/63891/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/6233/90135/56658/9870/51434/6468/26267/142685/4012/25847/90025/7327/10425/25793/51343/7311/26091/23295/6047/84541/7318/23194/51666/90293/131405/55175/55284/868/54461/9320/136371/80204/26232/29882/57520/26234/127247/27338/92591/7334/5930/11275/55182/84961/4591/23014/29116/26268/92369/115290/90678/51725/140459/997/23608/51676/55585/64320/51132/84261/7325/57542/9820/55658/7314/996/10324/283807/140691/899 253 Human_metapneumovirus R-HSA-983169 Class I MHC mediated antigen processing & presentation 269/1124 371/10654 1.4397318995526007e-187 8.911940458230598e-185 5.1375696205087535e-185 8454/9354/23643/57154/1147/197131/23352/26224/8945/10293/51088/140460/79754/6737/8065/64410/127544/114088/11065/285231/221687/9666/84937/57531/142678/55070/84708/246184/146330/55819/51320/93611/7319/54850/142686/8916/79791/26046/151636/7321/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/8697/7320/26235/10477/9817/10193/6890/148581/9039/223082/92912/154881/140739/25897/6500/6478/150726/390594/10533/81559/144699/140462/26259/57674/51130/10333/7099/53339/8517/154214/7336/200845/4615/79876/26263/64750/51619/6477/9690/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/9604/9978/22888/23304/7317/80196/114907/140456/64718/54926/4008/7335/7096/84861/11059/55236/84085/55958/54620/4734/84078/7337/26272/84676/27252/51444/7704/8651/3093/26118/222235/51433/25831/7322/5715/64219/10489/23327/9867/26249/140458/55905/55336/26270/143279/51465/63893/89122/6502/23291/118424/10616/929/27246/89910/55521/114609/25898/9903/201456/55294/26190/55008/7328/79654/10422/84727/135892/7428/22954/8453/401036/83737/51529/9040/695/90933/140461/7324/63891/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/6233/90135/56658/9870/51434/6468/26267/948/142685/4012/25847/90025/7327/10425/25793/51343/7311/26091/23295/6047/84541/7318/23194/51666/90293/131405/55175/55284/868/54461/9320/136371/80204/26232/29882/57520/26234/127247/27338/92591/7334/5930/11275/55182/7097/84961/4591/3551/23014/29116/26268/92369/1536/115290/90678/51725/140459/997/23608/51676/55585/64320/51132/84261/7325/57542/9820/55658/7314/996/4360/10324/283807/140691/899 269 Human_metapneumovirus R-HSA-8951664 Neddylation 157/1124 234/10654 1.2210947542752226e-98 5.039051019309085e-96 2.9049201522757926e-96 8454/9318/51397/26224/54165/8945/56995/23412/51088/9655/140460/79754/8065/64410/149951/29099/285231/23038/146330/93611/54850/142686/55884/79791/7321/51665/9616/122769/9021/4738/26235/9817/9039/154881/140739/6500/150726/390594/144699/140462/28952/26259/51130/53339/28991/200845/26263/140825/8452/8450/7323/9306/10517/89890/142689/7316/9978/114907/140456/4008/84861/64708/84085/55958/54620/84078/55527/26272/27252/7704/26118/222235/10980/7322/5715/122416/10489/26249/140458/55336/26270/6502/7347/23291/170622/90864/55832/10920/9903/201456/55294/26190/84727/10987/7428/8453/123879/401036/9040/140461/79176/80176/8139/23142/126433/10116/6233/90135/6468/2873/26267/142685/25793/7311/1154/84541/23194/83987/51666/90293/55175/8533/54461/136371/80204/26232/8835/26234/127247/8883/92591/11275/51122/84961/54939/23014/26268/92369/115290/54951/51725/140459/55208/84259/51676/84261/150684/50813/57542/9820/7314/51138/10324/8451/56929/283807/899 157 Human_metapneumovirus R-HSA-168898 Toll-like Receptor Cascades 110/1124 155/10654 7.046347936422546e-73 2.180844686322778e-70 1.2572168160248647e-70 54106/8454/23643/1147/3665/23098/3725/11035/4064/8945/1326/10695/351/81793/4790/6885/11213/7184/7321/8737/10392/653509/8767/5336/3684/1849/29110/5594/6271/1785/4214/6500/330/51295/23118/6280/10333/841/7099/8517/4615/7098/7100/338/5528/7323/7316/7335/7096/5970/4792/59307/6279/177/8651/26052/3146/7322/5519/64127/1432/329/23291/2244/929/114609/3656/57162/10454/3661/695/3654/7189/6285/6233/51311/10010/948/2266/51135/1385/81622/7311/1759/5518/2243/7187/1386/8772/9641/6197/5599/353376/5600/7334/7097/3929/3551/6416/5781/5608/9450/4791/51284/7314/5595/5515/148022/257397/5516 110 Human_metapneumovirus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 94/1124 129/10654 5.345236310202133e-64 1.323480510406048e-61 7.629621512246413e-62 8454/23643/1147/3665/23098/3725/11035/4064/8945/1326/351/4790/6885/11213/7321/8737/10392/653509/8767/5336/3684/1849/29110/5594/1785/4214/6500/330/51295/23118/10333/841/7099/8517/4615/5528/7323/7316/7335/7096/5970/4792/59307/177/8651/26052/3146/7322/5519/64127/1432/329/23291/929/114609/3656/57162/10454/3661/695/3654/7189/6285/6233/10010/948/51135/1385/7311/1759/5518/7187/1386/8772/9641/6197/5599/353376/5600/7334/7097/3929/3551/6416/5781/5608/9450/4791/7314/5595/5515/148022/257397/5516 94 Human_metapneumovirus R-HSA-449147 Signaling by Interleukins 181/1124 461/10654 2.262030173184891e-62 4.6673222573381584e-60 2.690625363893607e-60 5295/729230/8454/3605/3557/7124/1147/2308/834/3725/5777/8945/1326/596/9655/351/3592/5290/3566/1437/3667/4790/6885/2309/90865/5291/3561/11213/3587/7184/10392/27178/8767/3593/6775/207/3684/9021/1849/7422/29110/3553/1230/1439/5594/8878/3595/54472/2919/6500/5743/941/23118/4318/3383/8517/6778/3576/4615/3313/3662/3597/6776/5528/1436/7316/3565/9978/2920/3560/6352/6774/1435/7335/1441/5970/4792/6850/1026/6348/59307/3718/1440/3627/7133/3606/177/6772/8651/4609/3146/149233/5715/5519/64127/8503/3552/1432/867/3558/4067/3717/23291/4088/598/836/3320/4843/2534/3656/57162/3458/10454/998/7157/942/3654/3563/7189/6285/6233/2885/7525/1398/7006/948/6844/3716/84639/85480/7409/51135/8660/1385/9173/282618/7311/3594/1154/6347/3932/3575/5293/5518/2185/1386/5296/3687/51561/3570/6197/8835/5599/5600/7431/6777/7334/5008/3312/1399/3559/3929/3551/6773/7297/6416/5781/5608/3569/3162/3586/4791/3554/7314/3572/3596/5595/5515/257397/3556/5516 181 Human_metapneumovirus R-HSA-166166 MyD88-independent TLR4 cascade 71/1124 99/10654 1.1769583989946365e-47 1.8213431224442e-45 1.0499707822610047e-45 8454/23643/1147/3665/23098/3725/11035/8945/1326/351/4790/6885/7321/8737/10392/8767/1849/29110/5594/6500/330/23118/841/7099/8517/5528/7323/7316/7335/5970/4792/177/3146/7322/5519/64127/1432/329/23291/929/3656/10454/3661/3654/7189/6285/6233/10010/1385/7311/5518/7187/1386/8772/9641/6197/5599/353376/5600/7334/3551/6416/5781/5608/4791/7314/5595/5515/148022/257397/5516 71 Human_metapneumovirus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 71/1124 99/10654 1.1769583989946365e-47 1.8213431224442e-45 1.0499707822610047e-45 8454/23643/1147/3665/23098/3725/11035/8945/1326/351/4790/6885/7321/8737/10392/8767/1849/29110/5594/6500/330/23118/841/7099/8517/5528/7323/7316/7335/5970/4792/177/3146/7322/5519/64127/1432/329/23291/929/3656/10454/3661/3654/7189/6285/6233/10010/1385/7311/5518/7187/1386/8772/9641/6197/5599/353376/5600/7334/3551/6416/5781/5608/4791/7314/5595/5515/148022/257397/5516 71 Human_metapneumovirus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 67/1124 94/10654 9.970156127318817e-45 1.371450365068966e-42 7.906158893944044e-43 8454/1147/3665/23098/3725/11035/8945/1326/351/4790/6885/7321/8737/10392/8767/1849/29110/5594/6500/330/23118/841/8517/7098/5528/7323/7316/7335/5970/4792/177/3146/7322/5519/64127/1432/329/23291/3656/10454/3661/3654/7189/6285/6233/10010/1385/7311/5518/7187/1386/8772/9641/6197/5599/5600/7334/3551/6416/5608/4791/7314/5595/5515/148022/257397/5516 67 Human_metapneumovirus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 66/1124 95/10654 6.343084809897031e-43 7.138853631502294e-41 4.1154177044116615e-41 8454/23643/1147/3725/8945/1326/351/4790/6885/11213/10392/8767/1849/5594/4214/6500/51295/23118/10333/7099/8517/4615/5528/7316/7335/7096/5970/4792/59307/177/8651/3146/5519/64127/1432/23291/929/114609/3656/57162/10454/695/3654/7189/6285/6233/948/51135/1385/7311/5518/1386/6197/5599/5600/7334/7097/3551/6416/5608/4791/7314/5595/5515/257397/5516 66 Human_metapneumovirus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 66/1124 95/10654 6.343084809897031e-43 7.138853631502294e-41 4.1154177044116615e-41 8454/23643/1147/3725/8945/1326/351/4790/6885/11213/10392/8767/1849/5594/4214/6500/51295/23118/10333/7099/8517/4615/5528/7316/7335/7096/5970/4792/59307/177/8651/3146/5519/64127/1432/23291/929/114609/3656/57162/10454/695/3654/7189/6285/6233/948/51135/1385/7311/5518/1386/6197/5599/5600/7334/7097/3551/6416/5608/4791/7314/5595/5515/257397/5516 66 Human_metapneumovirus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 67/1124 98/10654 7.557837328375496e-43 7.197386625022202e-41 4.1491608976830654e-41 8454/23643/1147/3725/8945/1326/351/4790/6885/11213/10392/653509/8767/1849/5594/4214/6500/51295/23118/10333/7099/8517/4615/5528/7316/7335/7096/5970/4792/59307/177/8651/3146/5519/64127/1432/23291/929/114609/3656/57162/10454/695/3654/7189/6285/6233/948/51135/1385/7311/5518/1386/6197/5599/5600/7334/7097/3551/6416/5608/4791/7314/5595/5515/257397/5516 67 Human_metapneumovirus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 67/1124 98/10654 7.557837328375496e-43 7.197386625022202e-41 4.1491608976830654e-41 8454/23643/1147/3725/8945/1326/351/4790/6885/11213/10392/653509/8767/1849/5594/4214/6500/51295/23118/10333/7099/8517/4615/5528/7316/7335/7096/5970/4792/59307/177/8651/3146/5519/64127/1432/23291/929/114609/3656/57162/10454/695/3654/7189/6285/6233/948/51135/1385/7311/5518/1386/6197/5599/5600/7334/7097/3551/6416/5608/4791/7314/5595/5515/257397/5516 67 Human_metapneumovirus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 63/1124 93/10654 5.808649530407222e-40 4.794072079096094e-38 2.763694302888489e-38 54106/8454/23643/1147/3665/3725/8945/1326/351/4790/6885/10392/8767/1849/5594/4214/6500/51295/23118/7099/8517/4615/5528/7316/7335/5970/4792/177/3146/5519/64127/1432/23291/929/3656/57162/10454/3654/7189/6285/6233/51311/51135/1385/7311/5518/1386/6197/5599/353376/5600/7334/3551/6416/5608/4791/51284/7314/5595/5515/148022/257397/5516 63 Human_metapneumovirus R-HSA-975155 MyD88 dependent cascade initiated on endosome 63/1124 93/10654 5.808649530407222e-40 4.794072079096094e-38 2.763694302888489e-38 54106/8454/23643/1147/3665/3725/8945/1326/351/4790/6885/10392/8767/1849/5594/4214/6500/51295/23118/7099/8517/4615/5528/7316/7335/5970/4792/177/3146/5519/64127/1432/23291/929/3656/57162/10454/3654/7189/6285/6233/51311/51135/1385/7311/5518/1386/6197/5599/353376/5600/7334/3551/6416/5608/4791/51284/7314/5595/5515/148022/257397/5516 63 Human_metapneumovirus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 62/1124 92/10654 3.917019563812025e-39 3.030793887499554e-37 1.747196884384574e-37 54106/8454/23643/1147/3725/8945/1326/351/4790/6885/10392/8767/1849/5594/4214/6500/51295/23118/7099/8517/4615/5528/7316/7335/5970/4792/177/3146/5519/64127/1432/23291/929/3656/57162/10454/3654/7189/6285/6233/51311/51135/1385/7311/5518/1386/6197/5599/353376/5600/7334/3551/6416/5608/4791/51284/7314/5595/5515/148022/257397/5516 62 Human_metapneumovirus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 63/1124 97/10654 2.862336454756854e-38 2.084454429993521e-36 1.20164960763167e-36 54106/8454/23643/1147/3665/3725/8945/1326/351/4790/6885/10392/8767/1849/5594/4214/6500/51295/23118/7099/8517/4615/5528/7316/7335/5970/4792/177/3146/5519/64127/1432/23291/929/3656/57162/10454/3654/7189/6285/6233/51311/51135/1385/7311/5518/1386/6197/5599/353376/5600/7334/3551/6416/5608/4791/51284/7314/5595/5515/148022/257397/5516 63 Human_metapneumovirus R-HSA-1257604 PIP3 activates AKT signaling 106/1124 264/10654 2.887094011837164e-37 1.9856791036968937e-35 1.1447074503073668e-35 5295/1147/2308/5170/3725/23396/3643/5290/3667/2309/90865/23035/5291/5468/2065/5525/1822/23186/842/3815/572/23239/5526/10273/207/6045/5594/4303/84335/1027/7249/941/2064/57761/6199/4615/5528/2100/7316/4233/1026/55615/4734/6714/2099/64223/10014/5715/5519/8503/2932/2261/3164/10000/3084/2534/23512/5728/6009/5529/6615/3630/7157/23028/942/3654/7189/5371/208/6233/5527/2885/79109/2475/7409/51135/8660/1385/9173/7311/3932/2931/5293/5518/5155/1386/1956/4254/118788/5296/4343/117145/648/7874/5781/57521/23608/940/7314/5879/253260/5595/4193/5515/3556/5516 106 Human_metapneumovirus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 56/1124 85/10654 1.250932299837426e-34 7.374543748565397e-33 4.251288718244485e-33 8454/1147/3725/8945/1326/351/81793/4790/6885/10392/8767/1849/5594/4214/6500/51295/23118/8517/4615/7100/5528/7316/7335/5970/4792/177/3146/5519/64127/1432/23291/3656/57162/10454/3654/7189/6285/6233/51135/1385/7311/5518/1386/6197/5599/5600/7334/3551/6416/5608/4791/7314/5595/5515/257397/5516 56 Human_metapneumovirus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 56/1124 85/10654 1.250932299837426e-34 7.374543748565397e-33 4.251288718244485e-33 8454/1147/3725/8945/1326/351/81793/4790/6885/10392/8767/1849/5594/4214/6500/51295/23118/8517/4615/7100/5528/7316/7335/5970/4792/177/3146/5519/64127/1432/23291/3656/57162/10454/3654/7189/6285/6233/51135/1385/7311/5518/1386/6197/5599/5600/7334/3551/6416/5608/4791/7314/5595/5515/257397/5516 56 Human_metapneumovirus R-HSA-975871 MyD88 cascade initiated on plasma membrane 56/1124 85/10654 1.250932299837426e-34 7.374543748565397e-33 4.251288718244485e-33 8454/1147/3725/8945/1326/351/81793/4790/6885/10392/8767/1849/5594/4214/6500/51295/23118/8517/4615/7100/5528/7316/7335/5970/4792/177/3146/5519/64127/1432/23291/3656/57162/10454/3654/7189/6285/6233/51135/1385/7311/5518/1386/6197/5599/5600/7334/3551/6416/5608/4791/7314/5595/5515/257397/5516 56 Human_metapneumovirus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 53/1124 78/10654 7.009377941965892e-34 3.9443681327971704e-32 2.273855619451136e-32 1147/3443/3665/3441/351/4790/7321/8737/29110/57506/79132/4214/54476/3449/841/7706/8517/3444/7323/7316/5970/4792/177/3093/3146/23586/7322/3451/3448/64135/3440/83737/3661/9246/7189/6285/51191/6233/10010/7311/7318/7187/8772/5300/3452/9641/1540/3551/3456/4791/3446/7314/3445 53 Human_metapneumovirus R-HSA-9006925 Intracellular signaling by second messengers 108/1124 305/10654 3.571403745550276e-32 1.9223468856483663e-30 1.1081975924407723e-30 5295/1147/2308/5170/3725/23396/3643/5290/3667/5335/2309/90865/23035/5291/5468/2065/5525/1822/23186/842/3815/572/23239/5526/10273/207/6045/5594/4303/84335/1027/7249/941/2064/57761/6199/4615/5528/2100/7316/4233/1026/55615/4734/6714/2099/64223/10014/5715/5519/8503/2932/2261/3164/10000/3084/2534/23512/5728/6009/5529/6615/3630/7157/23028/942/3654/7189/5371/208/6233/5527/2885/79109/2475/7409/51135/8660/1385/9173/7311/3932/2931/5293/5518/5155/1386/1956/4254/118788/5296/4343/117145/648/7874/801/5781/57521/23608/940/7314/5879/253260/5595/4193/5515/3556/5516 108 Human_metapneumovirus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 42/1124 55/10654 1.755032761086515e-30 9.053043992604606e-29 5.218913210599373e-29 1147/834/596/351/4790/6885/842/10392/8767/10910/58484/7295/330/23118/841/8517/7316/7335/5970/64127/1432/329/598/3656/5603/10454/83737/3654/7189/6233/3326/7311/114548/5600/7334/1540/3551/6300/5608/4791/7314/257397 42 Human_metapneumovirus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 136/1124 473/10654 1.3530336203160877e-29 6.700222487805267e-28 3.8625549245234e-28 5295/54106/5170/5777/1173/3643/5590/4893/8065/857/5290/2670/3667/85440/5335/558/5291/1499/2065/5747/4690/526/3815/5430/10273/207/10019/1849/7422/5594/10193/2322/1785/3315/9101/10817/23118/51741/23385/4318/2064/57761/5921/6778/348/6776/5528/9306/7316/5753/5140/9047/6774/11059/4233/55615/4734/10413/6772/6714/2099/8651/26052/64223/5519/8503/1432/2261/867/5437/4067/3717/4914/529/10000/9146/3320/3084/2534/4846/4803/8471/1445/5603/3630/998/83737/3914/6285/208/6233/2885/7525/1398/79109/7410/7006/2475/7409/8660/1385/163/7311/3932/3479/1759/5518/5155/2185/387/1956/60/4254/5296/117145/6197/3845/5600/6777/3265/1399/6300/801/1020/5781/1536/3480/11140/53916/7314/5879/253260/5595/5515/6387/5516 136 Human_metapneumovirus R-HSA-199418 Negative regulation of the PI3K/AKT network 59/1124 110/10654 2.1298467598548393e-29 1.0141347264231889e-27 5.846300012880895e-28 5295/23396/3643/5290/3667/90865/23035/5291/2065/5525/3815/23239/5526/207/5594/941/2064/57761/4615/5528/2100/4233/6714/2099/5519/8503/2261/10000/3084/2534/5728/5529/3630/942/3654/7189/208/5527/2885/7409/51135/8660/9173/3932/5293/5518/5155/1956/4254/118788/5296/117145/5781/940/5879/5595/5515/3556/5516 59 Human_metapneumovirus R-HSA-2219528 PI3K/AKT Signaling in Cancer 56/1124 101/10654 5.813889668346472e-29 2.6657760775603455e-27 1.536770836311465e-27 5295/1147/2308/5170/5290/3667/2309/5291/2065/842/3815/572/207/4303/84335/1027/7249/941/2064/6199/2100/4233/1026/55615/6714/2099/64223/8503/2932/2261/3164/10000/3084/2534/5728/942/208/2885/79109/2475/7409/8660/1385/3932/2931/5293/5155/1956/4254/118788/5296/5781/940/5879/253260/4193 56 Human_metapneumovirus R-HSA-388841 Costimulation by the CD28 family 46/1124 70/10654 1.4427108584002303e-28 6.378843009641019e-27 3.677285571411113e-27 5295/5170/5777/1326/5290/5525/5526/207/5133/941/57761/5528/3122/9020/55615/3113/6714/64223/5519/8503/29126/4067/10000/2534/5529/1445/998/942/208/5527/2885/7525/79109/2475/7409/3932/5518/5296/117145/5781/1493/940/5879/253260/5515/5516 46 Human_metapneumovirus R-HSA-9009391 Extra-nuclear estrogen signaling 48/1124 77/10654 3.329673119901743e-28 1.4214259732546062e-26 8.19425907547507e-27 5295/2788/5170/596/5590/4893/857/5290/54331/2309/5747/59345/207/5594/1027/3315/10681/51764/94235/4318/2100/55970/2792/6714/2099/8503/2793/10000/3320/2785/4846/2783/2784/2782/2786/208/7514/1385/1956/5296/3845/3265/801/3480/2791/5595/2790/2787 48 Human_metapneumovirus R-HSA-5663202 Diseases of signal transduction 113/1124 377/10654 2.4970493762766748e-26 1.0304490426101744e-24 5.940349042510826e-25 5295/8454/1147/2308/5170/4893/5290/3667/5335/142678/2309/5291/1499/2065/10018/5525/892/842/55750/3815/572/5430/5526/207/5594/4303/84335/1027/7249/6500/941/10533/10013/23385/2064/6199/9208/6776/5528/2100/7316/9978/6774/4233/1026/55615/6772/6714/2099/4609/64223/10014/5715/5519/8503/2932/2261/867/5437/3717/4088/2244/3164/10000/3320/3084/2534/55294/5728/5529/1445/5894/4087/942/208/6233/5527/2885/79109/2475/2266/7409/8660/1385/7311/3932/2931/5293/5518/5155/2243/1956/60/4254/118788/5296/3845/6777/3265/369/801/5781/7750/11140/5245/940/7314/5879/253260/5595/4193/5515/5516 113 Human_metapneumovirus R-HSA-450294 MAP kinase activation 42/1124 64/10654 3.778214649291982e-26 1.50884830187854e-24 8.69823270702874e-25 8454/1147/3725/8945/1326/4790/6885/10392/8767/1849/5594/6500/23118/8517/5528/7316/7335/5519/64127/1432/23291/3656/10454/3654/7189/6233/1385/7311/5518/1386/6197/5599/5600/7334/3551/6416/5608/7314/5595/5515/257397/5516 42 Human_metapneumovirus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 55/1124 108/10654 5.48431442961123e-26 2.1217441449558448e-24 1.2231464418672415e-24 5295/3605/7124/2308/596/9655/3592/3566/2309/3561/7184/3593/207/3684/9021/7422/3553/5743/4318/3383/6778/3576/3662/3597/3565/6774/1026/3718/7133/3606/6772/8651/4609/149233/3552/3717/598/3320/4843/7157/948/3716/6347/3687/51561/3570/7431/5008/3312/3929/7297/3569/3162/3586/3596 55 Human_metapneumovirus R-HSA-168638 NOD1/2 Signaling Pathway 31/1124 36/10654 8.069709590043787e-26 3.027363779537639e-24 1.7452194902869816e-24 1147/834/6885/842/10392/8767/330/23118/841/8517/7316/7335/64127/1432/329/3656/5603/10454/83737/3654/7189/6233/7311/5600/7334/1540/3551/6300/5608/7314/257397 31 Human_metapneumovirus R-HSA-392451 G beta:gamma signalling through PI3Kgamma 25/1124 25/10654 2.9978680233594606e-25 1.0603887465482893e-23 6.1129459243239524e-24 2788/5170/54331/59345/207/10681/51764/94235/55970/2792/146850/2793/23533/10000/5294/2785/2783/2784/2782/2786/208/387/2791/2790/2787 25 Human_metapneumovirus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 25/1124 25/10654 2.9978680233594606e-25 1.0603887465482893e-23 6.1129459243239524e-24 1147/2308/5170/2309/842/572/207/4303/84335/1027/7249/6199/1026/55615/64223/2932/3164/10000/208/79109/2475/1385/2931/253260/4193 25 Human_metapneumovirus R-HSA-446652 Interleukin-1 family signaling 62/1124 140/10654 6.663413408491807e-25 2.2914738332535713e-23 1.3209924827360952e-23 8454/3557/1147/834/5777/8945/1326/351/4790/6885/90865/11213/10392/27178/8767/29110/3553/8878/54472/6500/23118/8517/4615/7316/3565/9978/6774/7335/5970/4792/59307/3606/177/3146/5715/64127/3552/23291/4088/3656/57162/10454/3654/7189/6285/6233/84639/51135/9173/7311/5599/7334/3551/6416/5781/5608/4791/3554/7314/3596/257397/3556 62 Human_metapneumovirus R-HSA-389356 CD28 co-stimulation 29/1124 33/10654 9.169527203385198e-25 3.0680742372407773e-23 1.7686883197425784e-23 5295/5170/1326/5290/207/941/57761/9020/55615/6714/64223/8503/4067/10000/2534/998/942/208/2885/7525/79109/2475/7409/3932/5296/117145/940/5879/253260 29 Human_metapneumovirus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 52/1124 103/10654 2.1100514250964554e-24 6.874325432287926e-23 3.962922067078661e-23 5295/23396/3643/5290/3667/90865/5291/2065/5525/3815/5526/207/5594/941/2064/4615/5528/2100/4233/6714/2099/5519/8503/2261/3084/2534/5529/3630/942/3654/7189/5527/2885/7409/51135/8660/9173/3932/5293/5518/5155/1956/4254/118788/5296/5781/940/5879/5595/5515/3556/5516 52 Human_metapneumovirus R-HSA-448424 Interleukin-17 signaling 43/1124 72/10654 2.6378499781878184e-24 8.373482751273126e-23 4.8271586645380317e-23 8454/3605/1147/3725/8945/1326/4790/6885/10392/8767/1849/5594/6500/23118/8517/5528/7316/7335/5519/64127/1432/23291/3656/10454/3654/7189/6233/1385/7311/5518/1386/6197/5599/5600/7334/3551/6416/5608/7314/5595/5515/257397/5516 43 Human_metapneumovirus R-HSA-5260271 Diseases of Immune System 24/1124 24/10654 2.8970306443919347e-24 8.747619360383452e-23 5.042841532471711e-23 23643/1147/81793/4790/10333/7099/8517/4615/7098/7100/7096/5970/4792/929/114609/695/948/51135/81622/7187/7097/3551/4791/148022 24 Human_metapneumovirus R-HSA-5602358 Diseases associated with the TLR signaling cascade 24/1124 24/10654 2.8970306443919347e-24 8.747619360383452e-23 5.042841532471711e-23 23643/1147/81793/4790/10333/7099/8517/4615/7098/7100/7096/5970/4792/929/114609/695/948/51135/81622/7187/7097/3551/4791/148022 24 Human_metapneumovirus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 34/1124 48/10654 4.3581774096314535e-23 1.2846246745532712e-21 7.405624771253448e-22 5295/5777/5290/1437/5291/3561/1439/6776/7316/3560/6850/3718/8503/867/3558/4067/3717/2534/3563/6233/2885/7525/1398/7006/3716/7409/7311/5293/5296/6777/1399/3559/5781/7314 34 Human_metapneumovirus R-HSA-389357 CD28 dependent PI3K/Akt signaling 22/1124 22/10654 2.6988159099927306e-22 7.770079294351165e-21 4.47930767925354e-21 5295/5170/1326/5290/207/941/57761/9020/55615/64223/8503/10000/2534/942/208/79109/2475/3932/5296/117145/940/253260 22 Human_metapneumovirus R-HSA-397795 G-protein beta:gamma signalling 27/1124 32/10654 3.81786914514568e-22 1.0742095458387163e-20 6.19262028805926e-21 2788/5170/54331/59345/207/10681/51764/94235/55970/2792/146850/2793/23533/10000/5294/2785/2783/2784/2782/998/695/2786/208/387/2791/2790/2787 27 Human_metapneumovirus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 27/1124 33/10654 1.8908644172212157e-21 5.2019781078219226e-20 2.9988446195929456e-20 1147/351/4790/6885/10392/8767/23118/8517/7316/7335/5970/4792/177/3146/64127/3656/10454/3654/7189/6285/6233/7311/7334/3551/4791/7314/257397 27 Human_metapneumovirus R-HSA-389513 CTLA4 inhibitory signaling 21/1124 21/10654 2.6016781116004403e-21 7.00190761339423e-20 4.036470845915557e-20 5525/5526/207/941/5528/6714/5519/4067/10000/2534/5529/942/208/5527/7525/3932/5518/5781/1493/5515/5516 21 Human_metapneumovirus R-HSA-937041 IKK complex recruitment mediated by RIP1 23/1124 25/10654 6.808864825892273e-21 1.7934839690329008e-19 1.0339104931590058e-19 23643/1147/23098/11035/7321/8737/330/7099/8517/7323/7316/7335/7322/329/929/7189/6233/7311/353376/7334/3551/7314/148022 23 Human_metapneumovirus R-HSA-4420097 VEGFA-VEGFR2 Pathway 47/1124 99/10654 9.92525891673868e-21 2.5598896956088514e-19 1.4757292863045667e-19 5295/5170/5590/4893/857/5290/5335/558/5291/1499/5747/4690/207/7422/3315/57761/5921/9047/55615/6714/64223/1432/10000/3320/2534/4846/5603/998/208/1398/79109/7410/2475/7409/2185/387/60/5296/117145/3845/5600/3265/6300/801/1536/5879/253260 47 Human_metapneumovirus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 25/1124 30/10654 2.5310104789084065e-20 6.394675454874709e-19 3.6864126846399562e-019 11065/7319/7321/65264/7320/10477/92912/7326/7316/7317/54926/55236/3093/7322/7347/7328/7324/6233/7327/7311/55284/27338/7874/997/7314 25 Human_metapneumovirus R-HSA-1433557 Signaling by SCF-KIT 30/1124 43/10654 3.284208819445926e-20 8.1317010369481135e-19 4.687775957019658e-19 5295/5777/4893/5290/3815/10019/4318/6776/9306/6774/6772/6714/8651/8503/867/4067/3717/2534/2885/7525/7006/7409/3932/4254/5296/3845/6777/3265/5781/5879 30 Human_metapneumovirus R-HSA-9020702 Interleukin-1 signaling 47/1124 103/10654 7.85198952393996e-20 1.9060319667917e-18 1.0987923420498024e-18 8454/3557/1147/8945/1326/351/4790/6885/11213/10392/8767/3553/8878/54472/6500/23118/8517/4615/7316/9978/7335/5970/4792/177/3146/5715/64127/3552/23291/3656/57162/10454/3654/7189/6285/6233/51135/7311/7334/3551/6416/5608/4791/3554/7314/257397/3556 47 Human_metapneumovirus R-HSA-6783783 Interleukin-10 signaling 31/1124 47/10654 1.0140451183805661e-19 2.4142074164521938e-18 1.3917461341336516e-18 729230/3557/7124/3592/1437/3587/3593/3553/1230/2919/5743/941/3383/3576/2920/6352/6774/1435/6348/1440/3627/7133/3606/3552/942/3716/6347/7297/3569/3586/3554 31 Human_metapneumovirus R-HSA-194138 Signaling by VEGF 47/1124 107/10654 5.460879845179656e-19 1.2755791034589462e-17 7.3534787190304e-18 5295/5170/5590/4893/857/5290/5335/558/5291/1499/5747/4690/207/7422/3315/57761/5921/9047/55615/6714/64223/1432/10000/3320/2534/4846/5603/998/208/1398/79109/7410/2475/7409/2185/387/60/5296/117145/3845/5600/3265/6300/801/1536/5879/253260 47 Human_metapneumovirus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 53/1124 134/10654 9.374282270548778e-19 2.14914100943322e-17 1.238940229908786e-17 5295/8454/1147/5170/3725/8945/4893/5290/5335/4790/6885/5291/7321/5336/5594/4214/6500/23118/8517/7316/7335/5970/4792/6850/8915/7322/5715/4067/23291/2534/10454/695/7189/6233/2885/7410/7006/7409/3702/7311/5296/3845/5599/7334/3265/3551/801/6416/997/7314/5879/5595/257397 53 Human_metapneumovirus R-HSA-8964315 G beta:gamma signalling through BTK 18/1124 18/10654 2.3194208863723184e-18 5.2208055587798725e-17 3.0096982984888645e-17 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/695/2786/2791/2790/2787 18 Human_metapneumovirus R-HSA-6804757 Regulation of TP53 Degradation 26/1124 36/10654 2.7638647890508576e-18 6.110115372937432e-17 3.522369035670078e-17 5170/207/11200/472/7316/890/80196/55615/64223/5519/10000/7157/208/6233/5527/79109/2475/7311/5518/7874/51230/7314/253260/4193/5515/5516 26 Human_metapneumovirus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 19/1124 20/10654 4.3476273076556735e-18 9.442741415574953e-17 5.4435666012752475e-17 1147/11035/7321/8737/330/8517/7098/7323/7316/7335/7322/329/7189/6233/7311/7334/3551/7314/148022 19 Human_metapneumovirus R-HSA-6806003 Regulation of TP53 Expression and Degradation 26/1124 37/10654 8.37237257796496e-18 1.7870684916414865e-16 1.030212088540879e-16 5170/207/11200/472/7316/890/80196/55615/64223/5519/10000/7157/208/6233/5527/79109/2475/7311/5518/7874/51230/7314/253260/4193/5515/5516 26 Human_metapneumovirus R-HSA-9006335 Signaling by Erythropoietin 21/1124 25/10654 2.1689399432014464e-17 4.551097711327781e-16 2.6236240526147736e-16 5295/4893/5290/5335/5291/5336/6776/4067/23533/3717/5294/2057/2885/2056/7409/8660/5293/3845/6777/3265/1399 21 Human_metapneumovirus R-HSA-392851 Prostacyclin signalling through prostacyclin receptor 18/1124 19/10654 3.9727606186138406e-17 8.197129409739891e-16 4.725494209509095e-16 2788/54331/59345/10681/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 18 Human_metapneumovirus R-HSA-9607240 FLT3 Signaling 76/1124 267/10654 1.4196590192825843e-16 2.8812096161833432e-15 1.660964305562713e-15 5295/54106/5170/2674/4893/5290/1437/3667/5291/2065/3561/5525/5747/3815/5526/1849/7010/1439/5594/2322/10817/2064/57761/5921/8452/6776/5528/7316/9978/3560/5140/4233/84078/3718/6714/5715/5519/2261/3558/3717/2244/3084/2534/5529/1445/5894/3563/208/6233/5527/2885/6709/3716/2266/8660/7311/5518/5155/2243/1956/60/4254/5296/117145/3845/6777/3265/3559/369/801/5781/5245/7314/5595/5515/5516 76 Human_metapneumovirus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 20/1124 24/10654 1.7560578467434343e-16 3.5064509907554383e-15 2.021404448373597e-15 6885/10392/8767/23118/8517/7316/7335/64127/1432/3656/10454/3654/7189/6233/7311/5600/7334/5608/7314/257397 20 Human_metapneumovirus R-HSA-1227986 Signaling by ERBB2 29/1124 50/10654 2.536231286074729e-16 4.98389576533415e-15 2.873124163673628e-15 5295/4893/8065/5290/5335/2065/10273/207/10193/9101/2064/7316/5753/6714/10000/3320/3084/2534/208/6233/2885/7525/7311/387/1956/3845/3265/11140/7314 29 Human_metapneumovirus R-HSA-912631 Regulation of signaling by CBL 19/1124 22/10654 2.7195780132541026e-16 5.260683719388405e-15 3.0326873239905946e-15 5295/5290/5291/7316/6850/8503/867/4067/2534/6233/2885/7525/1398/7409/7311/5293/5296/1399/7314 19 Human_metapneumovirus R-HSA-8964616 G beta:gamma signalling through CDC42 18/1124 20/10654 3.5814741609248034e-16 6.785278660845158e-15 3.911588242541465e-15 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/998/2786/2791/2790/2787 18 Human_metapneumovirus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 17/1124 18/10654 3.6173537287219743e-16 6.785278660845158e-15 3.911588242541465e-15 23643/3665/23098/29110/7099/7316/929/3661/6233/10010/7311/7187/9641/353376/5781/7314/148022 17 Human_metapneumovirus R-HSA-187037 Signaling by NTRK1 (TRKA) 37/1124 80/10654 3.988173807599374e-16 7.369192796728396e-15 4.248203993012373e-15 5295/1173/4893/5290/3667/5335/5291/1849/5594/1785/5528/6774/6714/26052/5519/1432/4914/4803/5603/2885/1398/8660/1385/163/1759/5518/387/5296/6197/3845/5600/3265/1399/6300/5595/5515/5516 37 Human_metapneumovirus R-HSA-166520 Signaling by NTRKs 42/1124 101/10654 4.671766877646997e-16 8.505363815480857e-15 4.903185670347777e-15 5295/1173/4893/5290/3667/5335/5291/1849/5594/1785/10817/5528/6774/6714/26052/5519/1432/4914/2534/4803/5603/2885/1398/8660/1385/163/1759/5518/387/5296/6197/3845/5600/3265/1399/6300/1020/5781/5879/5595/5515/5516 42 Human_metapneumovirus R-HSA-5683057 MAPK family signaling cascades 79/1124 294/10654 1.2723854737342283e-15 2.2829177050477892e-14 1.3160600323292246e-14 2308/3725/2674/4893/1437/3667/2309/2065/3561/5525/5747/3815/5526/1849/7010/1439/5594/2322/3315/10817/2064/5921/5596/8452/5528/7316/9978/3560/4233/5597/84078/3718/6714/4609/5715/5519/2261/3558/3717/2244/3084/2534/5529/1445/998/5894/3563/6233/5527/2885/6709/3716/2266/8660/7514/7311/5518/5155/2243/1956/60/4254/4343/3570/3845/3265/3559/369/801/7297/5781/3569/5245/7314/3572/5879/5595/5515/5516 79 Human_metapneumovirus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 19/1124 23/10654 1.4094905321298052e-15 2.457675040530562e-14 1.4168044192498262e-14 11065/246184/7321/991/8697/8881/7316/51433/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 19 Human_metapneumovirus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 19/1124 23/10654 1.4094905321298052e-15 2.457675040530562e-14 1.4168044192498262e-14 6885/10392/8767/23118/8517/7316/7335/64127/3656/10454/3654/7189/6233/7311/5599/7334/6416/7314/257397 19 Human_metapneumovirus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 23/1124 34/10654 2.536198281686933e-15 4.3608520454561424e-14 2.513950928338802e-14 7321/29110/57506/54476/7706/7323/7316/3093/23586/7322/64135/83737/3661/9246/51191/6233/7311/7318/7187/5300/9641/1540/7314 23 Human_metapneumovirus R-HSA-912694 Regulation of IFNA signaling 20/1124 26/10654 3.0900977587248244e-15 5.1842109735854314e-14 2.988602193768321e-14 3443/5777/3441/9021/3449/3444/6772/8651/3451/3448/3440/3454/3716/3452/3456/6773/7297/5781/3446/3445 20 Human_metapneumovirus R-HSA-5686938 Regulation of TLR by endogenous ligand 17/1124 19/10654 3.098801389703731e-15 5.1842109735854314e-14 2.988602193768321e-14 23643/653509/6271/6280/10333/7099/338/7096/6279/3146/2244/929/948/2266/2243/7097/3929 17 Human_metapneumovirus R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 16/1124 17/10654 3.2810528773868188e-15 5.415924616273176e-14 3.122180843323878e-14 23643/23098/6885/23118/7099/7316/929/3656/10454/7189/6233/7311/353376/7314/148022/257397 16 Human_metapneumovirus R-HSA-451927 Interleukin-2 family signaling 26/1124 44/10654 4.844928001410717e-15 7.699652673413696e-14 4.438708028717358e-14 5295/5777/5290/1437/5291/3561/6775/1439/6776/3560/6774/6850/3718/6772/8503/3558/3717/3563/2885/3716/3932/5293/2185/5296/6777/3559 26 Human_metapneumovirus R-HSA-186763 Downstream signal transduction 21/1124 29/10654 4.851154349969857e-15 7.699652673413696e-14 4.438708028717358e-14 5295/4893/5290/5335/5291/4690/5921/6778/6776/6774/6772/6714/2885/1398/5155/5296/3845/6777/3265/1399/5781 21 Human_metapneumovirus R-HSA-933541 TRAF6 mediated IRF7 activation 21/1124 29/10654 4.851154349969857e-15 7.699652673413696e-14 4.438708028717358e-14 3443/3665/3441/29110/57506/3449/7706/3444/23586/3451/3448/64135/3440/3661/7189/10010/3452/9641/3456/3446/3445 21 Human_metapneumovirus R-HSA-982772 Growth hormone receptor signaling 19/1124 24/10654 6.098252572460622e-15 9.556502132539557e-14 5.5091475604640914e-14 5777/3667/2690/9021/5594/6776/6774/6772/8651/4067/3717/5618/2688/8660/1154/8835/6777/2689/5595 19 Human_metapneumovirus R-HSA-8939211 ESR-mediated signaling 65/1124 223/10654 6.895079412030597e-15 1.0670135390117349e-13 6.151136633364138e-14 5295/2788/5170/3725/596/5590/4893/857/5290/54331/2309/5747/59345/5430/207/5594/1027/3315/10681/51764/94235/4318/200845/2100/865/55970/6667/2792/2289/6714/2099/4609/8503/5437/2793/10000/3320/8243/2785/4846/9126/2783/2784/2782/861/23028/2786/208/3326/7514/1385/1025/1386/1956/5296/4343/3845/3265/801/3480/2791/5595/2790/2787/6387 65 Human_metapneumovirus R-HSA-418217 G beta:gamma signalling through PLC beta 17/1124 20/10654 1.8629173906834094e-14 2.8472737403284703e-13 1.6414008978341148e-13 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Human_metapneumovirus R-HSA-198323 AKT phosphorylates targets in the cytosol 14/1124 14/10654 1.9677016034931252e-14 2.970749494054255e-13 1.7125823968784835e-13 1147/842/572/207/84335/1027/7249/1026/2932/10000/208/2931/23608/4193 14 Human_metapneumovirus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 19/1124 25/10654 2.2903693187380882e-14 3.375568114997325e-13 1.9459528798301047e-13 11065/246184/7321/991/8697/8881/7316/51433/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 19 Human_metapneumovirus R-HSA-418592 ADP signalling through P2Y purinoceptor 1 19/1124 25/10654 2.2903693187380882e-14 3.375568114997325e-13 1.9459528798301047e-13 2788/54331/59345/10681/51764/94235/55970/2792/6714/1432/2793/2785/2783/2784/2782/2786/2791/2790/2787 19 Human_metapneumovirus R-HSA-76002 Platelet activation, signaling and aggregation 71/1124 262/10654 2.3396854987807184e-14 3.40768311469474e-13 1.9644665859731606e-13 5295/2788/5170/5777/5590/351/5290/54331/5291/5747/59345/51097/5336/2316/207/813/7422/5594/10681/51764/94235/10447/335/51706/55970/5216/6850/2792/6714/8503/4352/146850/1432/3920/27154/2793/4067/23533/2244/9948/5294/2534/2785/2783/2784/1445/2782/998/5894/2786/2885/1398/7410/948/2266/7409/3932/3479/5155/2243/387/5296/213/801/5781/2791/5879/5595/2790/2787/139322 71 Human_metapneumovirus R-HSA-193639 p75NTR signals via NF-kB 15/1124 16/10654 2.9634656268271876e-14 4.216977524151791e-13 2.431009915291994e-13 4804/4790/8767/8878/4615/7316/5970/4792/4803/3654/7189/6233/7311/3551/7314 15 Human_metapneumovirus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 15/1124 16/10654 2.9634656268271876e-14 4.216977524151791e-13 2.431009915291994e-13 23643/6885/23118/7099/7316/929/3656/10454/7189/6233/7311/353376/7314/148022/257397 15 Human_metapneumovirus R-HSA-500657 Presynaptic function of Kainate receptors 17/1124 21/10654 8.819747321598364e-14 1.240778089106679e-12 7.152857277564223e-13 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Human_metapneumovirus R-HSA-114604 GPVI-mediated activation cascade 22/1124 35/10654 1.0264896494453096e-13 1.4278586359699925e-12 8.23134219188551e-13 5295/5170/5777/5590/5290/5291/5336/6850/8503/146850/4067/23533/5294/2534/998/7410/7409/3932/387/5296/5781/5879 22 Human_metapneumovirus R-HSA-418346 Platelet homeostasis 36/1124 88/10654 1.0864584676638935e-13 1.4944839810754447e-12 8.615425041825963e-13 2788/5777/54331/5525/59345/5526/10681/51764/94235/338/488/5528/55970/2778/2792/5519/1432/2793/4843/2785/4846/2783/2784/5529/2782/2786/5527/5518/801/5781/4842/2791/2790/5515/2787/5516 36 Human_metapneumovirus R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 16/1124 19/10654 1.5216514770710512e-13 2.0701148666087486e-12 1.1933831133073136e-12 11065/246184/7321/991/8697/8881/51433/51529/7324/64682/29945/10393/51434/51343/29882/996 16 Human_metapneumovirus R-HSA-209560 NF-kB is activated and signals survival 13/1124 13/10654 1.8846366123105628e-13 2.536065354391823e-12 1.4619949921585372e-12 4804/4790/8878/7316/5970/4792/4803/3654/7189/6233/7311/3551/7314 13 Human_metapneumovirus R-HSA-5684996 MAPK1/MAPK3 signaling 68/1124 255/10654 1.9621480585753814e-13 2.611977738189594e-12 1.5057570840001229e-12 2674/4893/1437/3667/2065/3561/5525/5747/3815/5526/1849/7010/1439/5594/2322/10817/2064/5921/8452/5528/7316/9978/3560/4233/84078/3718/6714/5715/5519/2261/3558/3717/2244/3084/2534/5529/1445/5894/3563/6233/5527/2885/6709/3716/2266/8660/7311/5518/5155/2243/1956/60/4254/3570/3845/3265/3559/369/801/7297/5781/3569/5245/7314/3572/5595/5515/5516 68 Human_metapneumovirus R-HSA-913531 Interferon Signaling 58/1124 199/10654 2.042361984129492e-13 2.6898341876088418e-12 1.5506398938855495e-12 3443/3665/3460/5777/3441/6737/5335/960/2316/9021/85363/9830/3383/3449/7706/3444/3662/7316/3122/3663/4734/3113/6772/8651/3659/23586/3459/6059/3451/3717/3448/3440/3458/3454/3661/7324/9246/5371/51191/4599/6233/684/3716/7311/81603/7318/5610/5300/3452/7334/3456/6773/7297/5781/3446/7314/3445/5595 58 Human_metapneumovirus R-HSA-5621481 C-type lectin receptors (CLRs) 47/1124 142/10654 2.44989396581774e-13 3.1925986628235395e-12 1.84047435880823e-12 8454/1147/5170/8945/4893/4790/6885/7321/5336/3553/9039/6500/23118/841/8517/7316/64581/9020/7335/5970/4792/6850/8915/6714/7322/5715/93978/4067/23291/2534/10454/9040/5894/7189/6233/30835/7311/3845/7334/3265/3551/801/997/26253/4791/7314/257397 47 Human_metapneumovirus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 14/1124 15/10654 2.6641644078874047e-13 3.4356620176714656e-12 1.9805959084952417e-12 54106/3665/4615/7316/7335/3654/7189/6233/51311/51135/7311/7334/51284/7314 14 Human_metapneumovirus R-HSA-392170 ADP signalling through P2Y purinoceptor 12 17/1124 22/10654 3.499648014130743e-13 4.4665610737050105e-12 2.5748902372009155e-12 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Human_metapneumovirus R-HSA-5607764 CLEC7A (Dectin-1) signaling 38/1124 101/10654 5.27793819837806e-13 6.667436213869427e-12 3.843654241138909e-12 8454/1147/5170/8945/4790/6885/7321/5336/3553/9039/6500/23118/841/8517/7316/64581/9020/7335/5970/4792/6850/8915/6714/7322/5715/23291/10454/9040/7189/6233/7311/7334/3551/801/997/4791/7314/257397 38 Human_metapneumovirus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 29/1124 63/10654 7.324907911585904e-13 9.159834337922575e-12 5.280475878846616e-12 1147/3665/170506/11035/6737/4790/1499/8737/29110/8517/6778/4615/7098/9208/5591/7316/5970/4792/5437/22954/1660/3661/6233/7311/3551/4791/7314/9533/148022 29 Human_metapneumovirus R-HSA-428930 Thromboxane signalling through TP receptor 17/1124 23/10654 1.2098428993516821e-12 1.4977855093973827e-11 8.63445774484674e-12 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Human_metapneumovirus R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 20/1124 32/10654 1.6242213701266698e-12 1.9908772833829873e-11 1.1477041052067556e-11 2788/54331/59345/5594/10681/51764/94235/55970/2792/6714/2793/2785/2783/2784/2782/2786/2791/5595/2790/2787 20 Human_metapneumovirus R-HSA-5218920 VEGFR2 mediated vascular permeability 19/1124 29/10654 1.7104473168826253e-12 2.0760135081379313e-11 1.196783571564933e-11 5170/857/1499/207/57761/55615/64223/10000/3320/4846/208/79109/7410/2475/7409/117145/801/5879/253260 19 Human_metapneumovirus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 12/1124 12/10654 1.803624355054765e-12 2.167851409279417e-11 1.2497264309934907e-11 3665/29110/7098/7316/3661/6233/10010/7311/7187/9641/7314/148022 12 Human_metapneumovirus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 14/1124 16/10654 1.923888932432015e-12 2.2901677868758024e-11 1.3202395710414028e-11 8454/1147/8945/1326/4790/6500/8517/7316/23291/6233/7311/3551/6416/7314 14 Human_metapneumovirus R-HSA-1236394 Signaling by ERBB4 27/1124 58/10654 3.268865189148282e-12 3.854147718252927e-11 2.221845211270712e-11 5295/4893/5290/2670/2065/23118/51741/23385/348/6776/7316/11059/4734/10413/6714/2099/3084/83737/6285/6233/2885/7311/1956/3845/3265/7314/6387 27 Human_metapneumovirus R-HSA-75893 TNF signaling 23/1124 43/10654 3.3294565453540903e-12 3.8885539652343057e-11 2.2416797792950083e-11 7124/1147/25999/81858/6885/8737/55072/330/23118/841/8517/7316/329/10616/10454/8567/6233/7311/8772/1540/3551/7314/257397 23 Human_metapneumovirus R-HSA-933542 TRAF6 mediated NF-kB activation 17/1124 24/10654 3.7409583314390894e-12 4.3283237517024226e-11 2.495198965780327e-11 1147/351/4790/57506/4214/7706/8517/5970/4792/177/3146/23586/64135/7189/6285/3551/4791 17 Human_metapneumovirus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 19/1124 30/10654 4.205313808393426e-12 4.8205356433250575e-11 2.778950060517293e-11 7124/1147/81858/6885/8737/55072/330/23118/8517/7316/329/10616/10454/6233/7311/1540/3551/7314/257397 19 Human_metapneumovirus R-HSA-912526 Interleukin receptor SHC signaling 18/1124 27/10654 4.278297387380797e-12 4.859203821630667e-11 2.8012415534951044e-11 5295/5777/5290/1437/5291/3561/1439/3560/3718/8503/3558/3717/3563/2885/3716/5293/5296/3559 18 Human_metapneumovirus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 15/1124 19/10654 5.27445579285006e-12 5.882681325719256e-11 3.391257494122656e-11 5295/4893/5290/5335/7316/867/3320/6233/2885/7311/1956/3845/3265/11140/7314 15 Human_metapneumovirus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 15/1124 19/10654 5.27445579285006e-12 5.882681325719256e-11 3.391257494122656e-11 5295/4893/5290/5335/7316/867/3320/6233/2885/7311/1956/3845/3265/11140/7314 15 Human_metapneumovirus R-HSA-9006931 Signaling by Nuclear Receptors 72/1124 299/10654 8.431961578777116e-12 9.314491804809998e-11 5.3696330615263816e-11 5295/2788/5170/3725/596/5590/4893/857/5290/54331/2309/5747/59345/5160/5430/207/64241/5594/1027/3315/10681/1737/51764/94235/4318/200845/348/2100/865/55970/6667/2792/2289/6714/2099/4609/8503/5437/2793/10000/3320/5162/8243/2785/4846/9126/2783/2784/2782/861/23028/2786/208/3326/7514/1385/1025/1738/1386/1956/5296/4343/3845/3265/801/29116/3480/2791/5595/2790/2787/6387 72 Human_metapneumovirus R-HSA-1268020 Mitochondrial protein import 28/1124 64/10654 8.501919014083439e-12 9.314491804809998e-11 5.3696330615263816e-11 90639/10063/56942/26520/3313/7416/400916/10440/54927/10165/1678/3329/56993/26521/25813/100272147/10469/4580/8604/26517/92609/10651/80273/9804/54543/388753/2671/131474 28 Human_metapneumovirus R-HSA-202403 TCR signaling 40/1124 119/10654 8.64203065652787e-12 9.384942063843424e-11 5.410246338989747e-11 5295/8454/1147/5170/8945/5290/5335/4790/6885/5291/4690/7321/8767/6500/23118/5788/8517/7316/3122/7335/5970/4792/8915/3113/7322/5715/23291/5728/1445/7189/6233/3702/26191/7311/3932/5296/7334/3551/997/7314 40 Human_metapneumovirus R-HSA-5689896 Ovarian tumor domain proteases 21/1124 38/10654 1.274964466029608e-11 1.3725269642996995e-10 7.912365290325622e-11 7321/8737/10392/8767/57506/7706/8517/7316/2099/23586/64127/64135/5728/7157/7189/6233/7311/7187/387/10318/7314 21 Human_metapneumovirus R-HSA-73887 Death Receptor Signalling 44/1124 141/10654 1.3788574772583859e-11 1.4715737559016222e-10 8.483351811081539e-11 7124/1147/25999/4804/81858/4790/6885/10018/572/8737/8767/55072/8878/355/330/23118/23385/841/8517/4615/7316/5970/4792/329/836/10616/4803/10454/8567/3654/7189/6233/7410/7409/7311/387/8772/5599/1540/3551/8743/7314/5879/257397 44 Human_metapneumovirus R-HSA-1059683 Interleukin-6 signaling 11/1124 11/10654 1.7247056613520063e-11 1.794273620801499e-10 1.034365712867457e-10 9021/6774/6772/867/3717/3716/3570/7297/5781/3569/3572 11 Human_metapneumovirus R-HSA-5603041 IRAK4 deficiency (TLR2/4) 11/1124 11/10654 1.7247056613520063e-11 1.794273620801499e-10 1.034365712867457e-10 23643/10333/7099/4615/7096/929/114609/695/948/51135/7097 11 Human_metapneumovirus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 11/1124 11/10654 1.7247056613520063e-11 1.794273620801499e-10 1.034365712867457e-10 6885/23118/7098/7316/10454/7189/6233/7311/7314/148022/257397 11 Human_metapneumovirus R-HSA-5673001 RAF/MAP kinase cascade 63/1124 249/10654 1.8650098972839622e-11 1.9240685440312876e-10 1.1091900968057248e-10 2674/4893/1437/3667/2065/3561/5525/5747/3815/5526/1849/7010/1439/5594/2322/10817/2064/5921/8452/5528/7316/9978/3560/4233/84078/3718/6714/5715/5519/2261/3558/3717/2244/3084/2534/5529/1445/5894/3563/6233/5527/2885/6709/3716/2266/8660/7311/5518/5155/2243/1956/60/4254/3845/3265/3559/369/801/5245/7314/5595/5515/5516 63 Human_metapneumovirus R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 15/1124 20/10654 1.9038896042675736e-11 1.9319797787567674e-10 1.1137507779925925e-10 11065/246184/7321/991/8697/8881/51433/51529/7324/64682/29945/10393/51434/29882/996 15 Human_metapneumovirus R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 15/1124 20/10654 1.9038896042675736e-11 1.9319797787567674e-10 1.1137507779925925e-10 11065/246184/7321/991/8697/8881/51433/51529/7324/64682/29945/10393/51434/29882/996 15 Human_metapneumovirus R-HSA-8852135 Protein ubiquitination 31/1124 79/10654 2.0606793806739355e-11 2.0740821733937658e-10 1.195670192637508e-10 11065/7319/7321/65264/7320/10477/92912/7336/7326/5591/7323/7316/7317/54926/55236/8915/3093/7322/7347/118424/7328/7324/6233/7327/7311/55284/27338/7334/7874/997/7314 31 Human_metapneumovirus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 12/1124 13/10654 2.11855526809393e-11 2.0982171375202283e-10 1.2095835551727872e-10 2065/207/10193/9101/2064/7316/10000/3084/208/6233/7311/7314 12 Human_metapneumovirus R-HSA-209543 p75NTR recruits signalling complexes 12/1124 13/10654 2.11855526809393e-11 2.0982171375202283e-10 1.2095835551727872e-10 4804/8767/8878/4615/7316/4803/3654/7189/6233/7311/3551/7314 12 Human_metapneumovirus R-HSA-392518 Signal amplification 19/1124 32/10654 2.173383939512062e-11 2.135435965965026e-10 1.2310395246359045e-10 2788/54331/59345/10681/51764/94235/55970/2792/6714/1432/2793/2785/2783/2784/2782/2786/2791/2790/2787 19 Human_metapneumovirus R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 30/1124 75/10654 2.4499011612056972e-11 2.3881713681674434e-10 1.3767368315768442e-10 5295/5290/3667/5291/2065/3815/941/2064/2100/4233/6714/2099/8503/2261/3084/2534/942/2885/7409/8660/3932/5293/5155/1956/4254/118788/5296/5781/940/5879 30 Human_metapneumovirus R-HSA-390466 Chaperonin-mediated protein folding 34/1124 95/10654 4.4827013633216837e-11 4.335612724837691e-10 2.499400924615215e-10 2788/26224/54331/59345/10681/5203/898/51764/94235/10517/55970/6774/2792/26272/2793/26270/7846/2785/55294/2783/26190/2784/2782/7157/2786/6468/10383/60/54461/26234/2791/84261/2790/2787 34 Human_metapneumovirus R-HSA-420092 Glucagon-type ligand receptors 19/1124 33/10654 4.618633327664338e-11 4.4324558601925973e-10 2.5552292094299644e-10 2788/2692/54331/59345/10681/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 19 Human_metapneumovirus R-HSA-5654741 Signaling by FGFR3 21/1124 40/10654 4.723778556693853e-11 4.4641510329671684e-10 2.573500893080299e-10 5295/4893/5290/5335/5594/10817/7316/6714/2261/867/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 21 Human_metapneumovirus R-HSA-5675221 Negative regulation of MAPK pathway 21/1124 40/10654 4.723778556693853e-11 4.4641510329671684e-10 2.573500893080299e-10 4893/5525/5526/1849/5594/5528/7316/5519/5529/5894/6233/5527/7311/5518/3845/3265/369/7314/5595/5515/5516 21 Human_metapneumovirus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 15/1124 21/10654 6.013547098455686e-11 5.639978263551621e-10 3.251343646533457e-10 1147/11035/4790/8737/29110/8517/4615/7098/5970/4792/1660/3661/3551/4791/148022 15 Human_metapneumovirus R-HSA-9609507 Protein localization 47/1124 163/10654 6.107528458825751e-11 5.685052806034796e-10 3.27732829052937e-10 1891/351/90639/10063/7321/51/10965/56942/26520/3313/7416/7323/7316/400916/10440/54927/10165/1678/3329/7322/56993/1962/26521/25813/100272147/118424/10469/4580/8604/4843/10455/26517/92609/10651/8540/6233/4358/6844/80273/9804/7311/54543/388753/2671/3162/131474/7314 47 Human_metapneumovirus R-HSA-909733 Interferon alpha/beta signaling 28/1124 69/10654 7.555824333339487e-11 6.980679496025587e-10 4.0242332270260585e-10 3443/3665/5777/3441/9021/3449/3444/3662/3663/6772/8651/3659/6059/3451/3448/3440/3454/3661/4599/684/3716/3452/3456/6773/7297/5781/3446/3445 28 Human_metapneumovirus R-HSA-1295596 Spry regulation of FGF signaling 13/1124 16/10654 7.773497996334569e-11 7.076169499604556e-10 4.079281456280834e-10 5594/7316/6714/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 13 Human_metapneumovirus R-HSA-1433559 Regulation of KIT signaling 13/1124 16/10654 7.773497996334569e-11 7.076169499604556e-10 4.079281456280834e-10 5777/3815/10019/9306/6714/8651/867/4067/2534/2885/7525/3932/4254 13 Human_metapneumovirus R-HSA-202424 Downstream TCR signaling 34/1124 98/10654 1.1946195728578972e-10 1.079517541020494e-9 6.223219903170606e-10 5295/8454/1147/5170/8945/5290/4790/6885/5291/7321/8767/6500/23118/8517/7316/3122/7335/5970/4792/8915/3113/7322/5715/23291/5728/7189/6233/7311/3932/5296/7334/3551/997/7314 34 Human_metapneumovirus R-HSA-176412 Phosphorylation of the APC/C 14/1124 19/10654 1.3715267386212462e-10 1.230398624937031e-9 7.093021577308962e-10 11065/246184/7321/8697/8881/51433/51529/7324/64682/29945/10393/51434/29882/996 14 Human_metapneumovirus R-HSA-2559583 Cellular Senescence 52/1124 195/10654 1.4268494493320984e-10 1.2708198692612502e-9 7.326042609974727e-10 3725/11065/4790/9448/246184/7027/7321/6045/8697/5594/1027/898/7295/472/3576/8881/7316/890/6774/5970/1026/6667/51433/1031/3552/1432/23512/7157/51529/7324/64682/29945/10393/6233/51434/51343/7311/4343/6197/29882/5599/648/5600/4217/3456/6416/5608/3569/7314/996/5595/4193 52 Human_metapneumovirus R-HSA-202040 G-protein activation 17/1124 28/10654 1.5359811867655485e-10 1.3486132689473397e-9 7.774507238723716e-10 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Human_metapneumovirus R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 17/1124 28/10654 1.5359811867655485e-10 1.3486132689473397e-9 7.774507238723716e-10 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Human_metapneumovirus R-HSA-5602498 MyD88 deficiency (TLR2/4) 10/1124 10/10654 1.6479144577585967e-10 1.4266560130805194e-9 8.22440929231011e-10 23643/10333/7099/4615/7096/929/114609/695/948/7097 10 Human_metapneumovirus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 10/1124 10/10654 1.6479144577585967e-10 1.4266560130805194e-9 8.22440929231011e-10 6885/23118/7316/3656/10454/7189/6233/7311/7314/257397 10 Human_metapneumovirus R-HSA-9020558 Interleukin-2 signaling 11/1124 12/10654 1.8712481145663812e-10 1.5976587350573655e-9 9.210208505814928e-10 3561/6776/3560/6850/3718/3558/3716/3932/2185/6777/3559 11 Human_metapneumovirus R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 11/1124 12/10654 1.8712481145663812e-10 1.5976587350573655e-9 9.210208505814928e-10 5295/5290/5291/4067/23533/3717/5294/2057/2056/8660/5293 11 Human_metapneumovirus R-HSA-3700989 Transcriptional Regulation by TP53 79/1124 365/10654 2.3064402337259768e-10 1.955734937912849e-9 1.1274451899540104e-9 9377/23774/834/5170/3725/64769/7862/7027/5430/7532/207/10971/1027/58484/7249/898/355/7295/7533/4292/11200/545/472/7316/890/80196/84289/1026/55615/6341/8148/64223/9150/5519/1432/27154/5437/51499/10000/51755/5728/6009/7994/7157/55215/5371/208/6233/5527/79109/2968/2475/1025/7311/51204/5518/6834/1386/5300/4343/6117/1340/1327/5600/4697/5564/7874/51230/5052/1020/2744/5608/57521/7248/7314/253260/4193/5515/5516 79 Human_metapneumovirus R-HSA-451326 Activation of kainate receptors upon glutamate binding 18/1124 32/10654 2.5657506001856894e-10 2.1462157047499212e-9 1.2372538456087463e-9 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/801/2791/2790/2787 18 Human_metapneumovirus R-HSA-5673000 RAF activation 18/1124 32/10654 2.5657506001856894e-10 2.1462157047499212e-9 1.2372538456087463e-9 4893/5525/5526/5528/6714/5519/3717/5529/5894/5527/5518/3845/3265/369/801/5245/5515/5516 18 Human_metapneumovirus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 13/1124 17/10654 2.983892250110434e-10 2.462705737091145e-9 1.419704523210438e-9 1147/11035/4790/8737/8517/4615/7098/5970/4792/1660/3551/4791/148022 13 Human_metapneumovirus R-HSA-432142 Platelet sensitization by LDL 13/1124 17/10654 2.983892250110434e-10 2.462705737091145e-9 1.419704523210438e-9 5777/5525/5526/338/5528/5519/1432/5529/5527/5518/5781/5515/5516 13 Human_metapneumovirus R-HSA-391251 Protein folding 34/1124 101/10654 3.0339415400211973e-10 2.4874302162557894e-9 1.4339577303132602e-9 2788/26224/54331/59345/10681/5203/898/51764/94235/10517/55970/6774/2792/26272/2793/26270/7846/2785/55294/2783/26190/2784/2782/7157/2786/6468/10383/60/54461/26234/2791/84261/2790/2787 34 Human_metapneumovirus R-HSA-8863795 Downregulation of ERBB2 signaling 17/1124 29/10654 3.348184876394441e-10 2.7270084716949465e-9 1.5720701843458662e-9 8065/2065/10273/207/10193/9101/2064/7316/10000/3320/3084/208/6233/7311/1956/11140/7314 17 Human_metapneumovirus R-HSA-5357905 Regulation of TNFR1 signaling 18/1124 33/10654 5.090415321088789e-10 4.118911220593412e-9 2.374476496524389e-9 7124/1147/25999/81858/8737/55072/330/841/8517/7316/329/10616/8567/6233/7311/1540/3551/7314 18 Human_metapneumovirus R-HSA-1170546 Prolactin receptor signaling 12/1124 15/10654 6.054597683665377e-10 4.804866623319062e-9 2.7699171589238364e-9 8454/8945/2690/6500/6776/9978/3717/5618/2688/6777/2689/5781 12 Human_metapneumovirus R-HSA-937039 IRAK1 recruits IKK complex 12/1124 15/10654 6.054597683665377e-10 4.804866623319062e-9 2.7699171589238364e-9 1147/8517/7316/7335/57162/3654/7189/6233/7311/7334/3551/7314 12 Human_metapneumovirus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 12/1124 15/10654 6.054597683665377e-10 4.804866623319062e-9 2.7699171589238364e-9 1147/8517/7316/7335/57162/3654/7189/6233/7311/7334/3551/7314 12 Human_metapneumovirus R-HSA-2424491 DAP12 signaling 17/1124 30/10654 6.969600889561743e-10 5.495774459412381e-9 3.168212807993873e-9 5295/4893/5290/5335/5291/5336/54209/6850/2534/695/2885/7410/3932/5296/3845/3265/5879 17 Human_metapneumovirus R-HSA-5654743 Signaling by FGFR4 20/1124 41/10654 7.606693264732641e-10 5.960181178315829e-9 3.4359347325041507e-9 5295/4893/5290/5335/5594/10817/7316/6714/867/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 20 Human_metapneumovirus R-HSA-5357801 Programmed Cell Death 48/1124 181/10654 8.99013385043158e-10 6.999865224424085e-9 4.035293446271175e-9 23643/2934/11035/596/1499/4976/10018/5747/7027/842/572/8737/7532/207/10971/5594/10059/355/330/7533/841/7099/7316/6774/5339/4836/115209/3146/5715/329/598/836/929/10000/7157/208/6233/6709/7311/8772/5599/353376/7431/26060/8743/7314/5595/148022 48 Human_metapneumovirus R-HSA-74751 Insulin receptor signalling cascade 23/1124 54/10654 1.1965274516008172e-9 9.143833241245752e-9 5.271251541165394e-9 5295/54106/5170/3643/4893/5290/3667/5291/5594/2322/57761/5140/2261/3630/208/2885/8660/5296/117145/3845/3265/5781/5595 23 Human_metapneumovirus R-HSA-8848021 Signaling by PTK6 23/1124 54/10654 1.1965274516008172e-9 9.143833241245752e-9 5.271251541165394e-9 4893/2065/207/9021/55620/1027/898/2064/5921/7316/5753/6774/867/3084/6233/1398/7311/387/1956/3845/3265/7314/5879 23 Human_metapneumovirus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 23/1124 54/10654 1.1965274516008172e-9 9.143833241245752e-9 5.271251541165394e-9 4893/2065/207/9021/55620/1027/898/2064/5921/7316/5753/6774/867/3084/6233/1398/7311/387/1956/3845/3265/7314/5879 23 Human_metapneumovirus R-HSA-2586552 Signaling by Leptin 10/1124 11/10654 1.640235337399261e-9 1.2457738329449603e-8 7.181656821160471e-9 3667/3953/9021/3952/6776/6774/3717/8660/6777/5781 10 Human_metapneumovirus R-HSA-1643713 Signaling by EGFR in Cancer 15/1124 25/10654 2.4035796226609565e-9 1.814409495642844e-8 1.0459736740462955e-8 5295/4893/5290/5335/7316/867/3320/6233/2885/7311/1956/3845/3265/11140/7314 15 Human_metapneumovirus R-HSA-2871796 FCERI mediated MAPK activation 17/1124 32/10654 2.6790672610513512e-9 2.0101122843524684e-8 1.1587927291820199e-8 3725/4893/5335/5336/5594/4214/6850/4067/2885/7410/7409/3845/5599/3265/6416/5879/5595 17 Human_metapneumovirus R-HSA-2428928 IRS-related events triggered by IGF1R 22/1124 52/10654 3.205745387037949e-9 2.3907908368391452e-8 1.3782469070461186e-8 5295/54106/5170/4893/5290/3667/5291/2322/57761/5140/2261/8471/208/2885/8660/3479/5296/117145/3845/3265/5781/3480 22 Human_metapneumovirus R-HSA-69231 Cyclin D associated events in G1 20/1124 44/10654 3.6471154641144602e-9 2.6875767527224412e-8 1.549338524229075e-8 8454/25/7027/1027/6500/7316/5753/1026/6714/1031/5519/4067/3717/6502/6233/7311/5518/7314/5515/5516 20 Human_metapneumovirus R-HSA-69236 G1 Phase 20/1124 44/10654 3.6471154641144602e-9 2.6875767527224412e-8 1.549338524229075e-8 8454/25/7027/1027/6500/7316/5753/1026/6714/1031/5519/4067/3717/6502/6233/7311/5518/7314/5515/5516 20 Human_metapneumovirus R-HSA-9027284 Erythropoietin activates RAS 11/1124 14/10654 4.641013424303004e-9 3.399748295436165e-8 1.959892308737114e-8 4893/4067/3717/2057/2885/2056/7409/8660/3845/3265/1399 11 Human_metapneumovirus R-HSA-2428924 IGF1R signaling cascade 22/1124 53/10654 4.939833000465635e-9 3.583860935017307e-8 2.0660298562551942e-8 5295/54106/5170/4893/5290/3667/5291/2322/57761/5140/2261/8471/208/2885/8660/3479/5296/117145/3845/3265/5781/3480 22 Human_metapneumovirus R-HSA-109581 Apoptosis 46/1124 178/10654 4.950244102487556e-9 3.583860935017307e-8 2.0660298562551942e-8 23643/2934/596/1499/4976/10018/5747/7027/842/572/8737/7532/207/10971/5594/10059/355/7533/841/7099/7316/6774/5339/4836/115209/3146/5715/329/598/836/929/10000/7157/208/6233/6709/7311/8772/5599/353376/7431/26060/8743/7314/5595/148022 46 Human_metapneumovirus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 29/1124 86/10654 5.872050037418004e-9 4.2265104339090054e-8 2.4365054622823784e-8 5295/25/5290/5335/5291/5747/4690/5336/4771/5594/4644/6850/6714/4067/3320/2534/998/695/2885/7525/1398/7410/10096/3326/7409/60/5296/5879/5595 29 Human_metapneumovirus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 34/1124 112/10654 6.460026403193559e-9 4.622839703557009e-8 2.6649819904869074e-8 5295/8454/1147/5777/8945/4893/4790/6885/5966/4690/5336/6500/8517/7316/5970/4792/6850/8915/5715/4067/23291/2534/695/6233/2885/7409/7311/5293/118788/3845/3265/3551/801/7314 34 Human_metapneumovirus R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 22/1124 54/10654 7.513355565310188e-9 5.3457093045138e-8 3.081703008639024e-8 5295/54106/5170/4893/5290/3667/5291/2322/57761/5140/2261/8471/208/2885/8660/3479/5296/117145/3845/3265/5781/3480 22 Human_metapneumovirus R-HSA-2871837 FCERI mediated NF-kB activation 28/1124 82/10654 7.813203080617752e-9 5.52728309360273e-8 3.1863769555842623e-008 8454/1147/5170/8945/4790/6885/7321/6500/23118/8517/7316/7335/5970/4792/8915/7322/5715/4067/23291/10454/7189/6233/7311/7334/3551/997/7314/257397 28 Human_metapneumovirus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 10/1124 12/10654 8.90578796711236e-9 6.264412217775626e-8 3.611318326376902e-8 1147/8737/57506/841/7706/8517/23586/64135/8772/3551 10 Human_metapneumovirus R-HSA-170834 Signaling by TGF-beta Receptor Complex 26/1124 73/10654 9.741542929702764e-9 6.813576354221481e-8 3.9279013418605256e-8 57154/5590/892/7027/7321/6497/10273/4738/64750/7323/54778/7316/6667/4609/23327/867/4088/142/9040/4087/6233/7514/1025/7311/387/7314 26 Human_metapneumovirus R-HSA-5696394 DNA Damage Recognition in GG-NER 18/1124 38/10654 9.834081168858873e-9 6.839658700588362e-8 3.9429373344094117e-8 9318/8450/7316/9978/64708/10980/10920/142/10987/6233/2873/7311/60/8533/50813/7314/51138/8451 18 Human_metapneumovirus R-HSA-2262752 Cellular responses to stress 91/1124 479/10654 1.1384019675411672e-8 7.873416959865726e-8 4.538879941152081e-8 3725/11065/4790/9448/246184/112399/7027/526/7321/6045/7422/8697/5594/3308/84335/1027/898/7295/10294/10013/545/472/3576/3313/8881/7323/7316/9978/890/10935/6774/5970/1026/832/6667/2289/51433/64223/1031/7322/5715/3552/1432/2932/7846/3310/529/3320/23512/6009/3301/25994/7428/7157/8453/51529/50507/7324/64682/29945/10393/6233/2056/51434/3326/2475/51343/7311/10383/23411/4343/6117/6197/29882/5599/648/5600/54583/3312/4217/3456/5052/6416/1536/5608/3569/57521/7314/996/5595/4193 91 Human_metapneumovirus R-HSA-5633007 Regulation of TP53 Activity 42/1124 160/10654 1.4074472435373548e-8 9.680109374995808e-8 5.58040486034109e-8 23774/5170/64769/7862/207/11200/545/472/7316/890/80196/84289/55615/8148/64223/5519/1432/27154/10000/7994/7157/5371/208/6233/5527/79109/2475/7311/5518/5300/6117/5600/5564/7874/51230/1020/5608/7314/253260/4193/5515/5516 42 Human_metapneumovirus R-HSA-2562578 TRIF-mediated programmed cell death 9/1124 10/10654 1.4249656721506289e-8 9.746450287969495e-8 5.618649175447086e-8 23643/11035/8737/841/7099/929/8772/353376/148022 9 Human_metapneumovirus R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 33/1124 110/10654 1.4937278275292285e-8 1.0160632145501015e-7 5.857417391930693e-8 3725/11065/4790/246184/7321/8697/5594/1027/3576/8881/7316/890/6774/5970/1026/51433/1031/3552/51529/7324/64682/29945/10393/6233/51434/51343/7311/6197/29882/3569/7314/996/5595 33 Human_metapneumovirus R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 11/1124 15/10654 1.5738785978128234e-8 1.025506160048566e-7 5.911854234443735e-8 1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 11 Human_metapneumovirus R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 11/1124 15/10654 1.5738785978128234e-8 1.025506160048566e-7 5.911854234443735e-8 1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 11 Human_metapneumovirus R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 11/1124 15/10654 1.5738785978128234e-8 1.025506160048566e-7 5.911854234443735e-8 1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 11 Human_metapneumovirus R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 11/1124 15/10654 1.5738785978128234e-8 1.025506160048566e-7 5.911854234443735e-8 1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 11 Human_metapneumovirus R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 11/1124 15/10654 1.5738785978128234e-8 1.025506160048566e-7 5.911854234443735e-8 1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 11 Human_metapneumovirus R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 11/1124 15/10654 1.5738785978128234e-8 1.025506160048566e-7 5.911854234443735e-8 1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 11 Human_metapneumovirus R-HSA-5637810 Constitutive Signaling by EGFRvIII 11/1124 15/10654 1.5738785978128234e-8 1.025506160048566e-7 5.911854234443735e-8 5295/4893/5290/5335/867/3320/2885/1956/3845/3265/11140 11 Human_metapneumovirus R-HSA-5637812 Signaling by EGFRvIII in Cancer 11/1124 15/10654 1.5738785978128234e-8 1.025506160048566e-7 5.911854234443735e-8 5295/4893/5290/5335/867/3320/2885/1956/3845/3265/11140 11 Human_metapneumovirus R-HSA-8953897 Cellular responses to external stimuli 91/1124 493/10654 4.7713753614222173e-8 3.092650626932306e-7 1.7828561559902249e-7 3725/11065/4790/9448/246184/112399/7027/526/7321/6045/7422/8697/5594/3308/84335/1027/898/7295/10294/10013/545/472/3576/3313/8881/7323/7316/9978/890/10935/6774/5970/1026/832/6667/2289/51433/64223/1031/7322/5715/3552/1432/2932/7846/3310/529/3320/23512/6009/3301/25994/7428/7157/8453/51529/50507/7324/64682/29945/10393/6233/2056/51434/3326/2475/51343/7311/10383/23411/4343/6117/6197/29882/5599/648/5600/54583/3312/4217/3456/5052/6416/1536/5608/3569/57521/7314/996/5595/4193 91 Human_metapneumovirus R-HSA-5654736 Signaling by FGFR1 20/1124 50/10654 5.243862704906149e-8 3.381198973267611e-7 1.949198965968404e-7 5295/4893/5290/5335/5594/10817/7316/6714/867/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 20 Human_metapneumovirus R-HSA-611105 Respiratory electron transport 30/1124 100/10654 6.725942269682304e-8 4.3143608963039856e-7 2.4871496366755393e-7 51300/9377/4722/4723/4702/7388/4719/55863/4704/2109/51295/4729/7386/6389/6341/7385/4728/4725/27089/2108/4726/7384/51204/6834/4698/1340/1327/4697/4720/51079 30 Human_metapneumovirus R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 18/1124 42/10654 6.85751179900926e-8 4.3760822717388987e-7 2.5227308734282573e-7 2788/54331/59345/10681/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 18 Human_metapneumovirus R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 9/1124 11/10654 7.099205294998801e-8 4.5070852077992387e-7 2.598251654525877e-7 6885/23118/7316/10454/7189/6233/7311/7314/257397 9 Human_metapneumovirus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 13/1124 23/10654 7.794899064192754e-8 4.923512776260525e-7 2.8383144820207774e-7 7321/6497/64750/7323/54778/7316/23327/4088/142/4087/6233/7311/7314 13 Human_metapneumovirus R-HSA-5213460 RIPK1-mediated regulated necrosis 12/1124 20/10654 1.0109998625738704e-7 6.289536833499756e-7 3.625802204840434e-7 11035/8737/355/330/841/7316/329/6233/7311/8772/8743/7314 12 Human_metapneumovirus R-HSA-5218859 Regulated Necrosis 12/1124 20/10654 1.0109998625738704e-7 6.289536833499756e-7 3.625802204840434e-7 11035/8737/355/330/841/7316/329/6233/7311/8772/8743/7314 12 Human_metapneumovirus R-HSA-622312 Inflammasomes 12/1124 20/10654 1.0109998625738704e-7 6.289536833499756e-7 3.625802204840434e-7 834/596/351/4790/10910/58484/7295/5970/598/3326/114548/4791 12 Human_metapneumovirus R-HSA-2172127 DAP12 interactions 18/1124 43/10654 1.0640055296385292e-7 6.553427092997508e-7 3.7779300816701897e-7 5295/4893/5290/5335/5291/5336/54209/6850/54210/2534/695/2885/7410/3932/5296/3845/3265/5879 18 Human_metapneumovirus R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 18/1124 43/10654 1.0640055296385292e-7 6.553427092997508e-7 3.7779300816701897e-7 2788/54331/59345/10681/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 18 Human_metapneumovirus R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 10/1124 14/10654 1.1063769203534497e-7 6.553562810514692e-7 3.778008320320518e-7 5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 10 Human_metapneumovirus R-HSA-4839744 truncated APC mutants destabilize the destruction complex 10/1124 14/10654 1.1063769203534497e-7 6.553562810514692e-7 3.778008320320518e-7 5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 10 Human_metapneumovirus R-HSA-4839748 AMER1 mutants destabilize the destruction complex 10/1124 14/10654 1.1063769203534497e-7 6.553562810514692e-7 3.778008320320518e-7 5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 10 Human_metapneumovirus R-HSA-5467337 APC truncation mutants have impaired AXIN binding 10/1124 14/10654 1.1063769203534497e-7 6.553562810514692e-7 3.778008320320518e-7 5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 10 Human_metapneumovirus R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 10/1124 14/10654 1.1063769203534497e-7 6.553562810514692e-7 3.778008320320518e-7 5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 10 Human_metapneumovirus R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 10/1124 14/10654 1.1063769203534497e-7 6.553562810514692e-7 3.778008320320518e-7 5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 10 Human_metapneumovirus R-HSA-877312 Regulation of IFNG signaling 10/1124 14/10654 1.1063769203534497e-7 6.553562810514692e-7 3.778008320320518e-7 3460/5777/9021/6772/8651/3459/3717/3458/3716/5781 10 Human_metapneumovirus R-HSA-918233 TRAF3-dependent IRF activation pathway 10/1124 14/10654 1.1063769203534497e-7 6.553562810514692e-7 3.778008320320518e-7 3665/29110/57506/7706/23586/64135/3661/7187/9641/3456 10 Human_metapneumovirus R-HSA-196299 Beta-catenin phosphorylation cascade 11/1124 17/10654 1.1672626659316227e-7 6.88129133534928e-7 3.966937781963108e-7 1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 11 Human_metapneumovirus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 15/1124 31/10654 1.1959423874868675e-7 7.016951069709678e-7 4.0451431215569777e-7 3725/1849/5594/5528/5519/1432/1385/5518/1386/6197/5599/5600/5595/5515/5516 15 Human_metapneumovirus R-HSA-9612973 Autophagy 33/1124 119/10654 1.2244454406410845e-7 7.150299318460673e-7 4.122015932247544e-7 2670/8878/7249/1080/10533/10013/64419/7416/192111/7316/51271/8678/6714/64223/56993/3920/3320/6009/55054/6233/3326/2475/9804/7311/54543/55626/7251/7431/3312/5564/57521/7248/7314 33 Human_metapneumovirus R-HSA-112399 IRS-mediated signalling 19/1124 48/10654 1.3798672923157735e-7 8.020073745948016e-7 4.623424878626609e-7 5295/54106/5170/4893/5290/3667/5291/2322/57761/5140/2261/208/2885/8660/5296/117145/3845/3265/5781 19 Human_metapneumovirus R-HSA-4086398 Ca2+ pathway 22/1124 62/10654 1.4397775760628325e-7 8.32918055684947e-7 4.801619264980819e-7 2788/54331/6885/1499/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/4343/3845/801/2791/2790/2787 22 Human_metapneumovirus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 18/1124 44/10654 1.6243754887992362e-7 9.353380721550951e-7 5.39205180614875e-7 892/7027/7321/6497/64750/7323/54778/7316/6667/4609/23327/4088/142/4087/6233/1025/7311/7314 18 Human_metapneumovirus R-HSA-109606 Intrinsic Pathway for Apoptosis 20/1124 53/10654 1.6508941877957692e-7 9.462069465236863e-7 5.454708866108829e-7 596/10018/7027/842/572/7532/207/10971/5594/7533/841/6774/4836/598/836/10000/7157/208/5599/5595 20 Human_metapneumovirus R-HSA-186797 Signaling by PDGF 21/1124 58/10654 1.8581428270797983e-7 1.0600833271542813e-6 6.111185237740012e-7 5295/4893/5290/5335/5291/4690/5921/6778/6776/6774/6772/6714/2885/1398/5155/5296/3845/6777/3265/1399/5781 21 Human_metapneumovirus R-HSA-1266695 Interleukin-7 signaling 16/1124 36/10654 1.9991955835890919e-7 1.1353229965519704e-6 6.544928081474671e-7 5295/3667/3561/6776/6774/3718/8651/8503/3716/85480/8660/1154/3575/5296/8835/6777 16 Human_metapneumovirus R-HSA-74752 Signaling by Insulin receptor 25/1124 78/10654 2.020624348769324e-7 1.142252485742659e-6 6.584875311057926e-7 5295/54106/5170/3643/4893/5290/3667/5291/526/5594/2322/57761/5140/2261/529/3630/208/2885/8660/5296/117145/3845/3265/5781/5595 25 Human_metapneumovirus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 20/1124 54/10654 2.364500086730912e-7 1.3305686851694858e-6 7.670483534945255e-7 9318/5430/8450/7316/9978/64708/10980/5437/10920/10987/6233/2873/2968/7311/8533/7874/50813/7314/51138/8451 20 Human_metapneumovirus R-HSA-389359 CD28 dependent Vav1 pathway 9/1124 12/10654 2.5725084789861525e-7 1.4345790526958814e-6 8.270084157195881e-7 941/2534/998/942/2885/7409/3932/940/5879 9 Human_metapneumovirus R-HSA-8984722 Interleukin-35 Signalling 9/1124 12/10654 2.5725084789861525e-7 1.4345790526958814e-6 8.270084157195881e-7 3592/6775/3595/6774/6772/3717/3716/7297/3572 9 Human_metapneumovirus R-HSA-210993 Tie2 Signaling 11/1124 18/10654 2.714980127185994e-7 1.5005113381501164e-6 8.650171645827556e-7 5295/4893/5290/5291/7010/2888/2885/5296/3845/3265/5781 11 Human_metapneumovirus R-HSA-5675482 Regulation of necroptotic cell death 11/1124 18/10654 2.714980127185994e-7 1.5005113381501164e-6 8.650171645827556e-7 8737/355/330/841/7316/329/6233/7311/8772/8743/7314 11 Human_metapneumovirus R-HSA-1296041 Activation of G protein gated Potassium channels 13/1124 25/10654 2.8926749895958216e-7 1.570671770666503e-6 9.0546336239426e-7 2788/54331/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 13 Human_metapneumovirus R-HSA-1296059 G protein gated Potassium channels 13/1124 25/10654 2.8926749895958216e-7 1.570671770666503e-6 9.0546336239426e-7 2788/54331/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 13 Human_metapneumovirus R-HSA-9006115 Signaling by NTRK2 (TRKB) 13/1124 25/10654 2.8926749895958216e-7 1.570671770666503e-6 9.0546336239426e-7 5295/4893/5290/5335/10817/6714/2534/2885/3845/3265/1020/5781/5879 13 Human_metapneumovirus R-HSA-997272 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits 13/1124 25/10654 2.8926749895958216e-7 1.570671770666503e-6 9.0546336239426e-7 2788/54331/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 13 Human_metapneumovirus R-HSA-5654732 Negative regulation of FGFR3 signaling 14/1124 29/10654 3.298505348912362e-7 1.7832094419010935e-6 1.0279874174040825e-6 5594/7316/6714/2261/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 14 Human_metapneumovirus R-HSA-163359 Glucagon signaling in metabolic regulation 15/1124 33/10654 3.36448176371939e-7 1.8109688797759152e-6 1.0439902223348954e-6 2788/54331/59345/51764/94235/55970/2778/2785/2783/2784/2782/2786/2791/2790/2787 15 Human_metapneumovirus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 25/1124 80/10654 3.4920648186921773e-7 1.8715048681995305e-6 1.0788881052965578e-6 8454/8945/11065/246184/7321/991/8697/6500/8881/7316/890/51433/5715/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/7314/996 25 Human_metapneumovirus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 26/1124 86/10654 4.2339334384469957e-7 2.234409504043914e-6 1.2880959474039399e-6 8454/8945/11065/246184/7321/991/8697/6500/8881/7316/890/51433/5715/6502/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/7314/996 26 Human_metapneumovirus R-HSA-453276 Regulation of mitotic cell cycle 26/1124 86/10654 4.2339334384469957e-7 2.234409504043914e-6 1.2880959474039399e-6 8454/8945/11065/246184/7321/991/8697/6500/8881/7316/890/51433/5715/6502/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/7314/996 26 Human_metapneumovirus R-HSA-5628897 TP53 Regulates Metabolic Genes 26/1124 86/10654 4.2339334384469957e-7 2.234409504043914e-6 1.2880959474039399e-6 9377/7532/207/10971/7249/7295/7533/6341/64223/10000/5728/6009/7157/208/2475/51204/6834/4343/1340/1327/4697/5564/5052/2744/57521/7248 26 Human_metapneumovirus R-HSA-9613829 Chaperone Mediated Autophagy 12/1124 22/10654 4.2414073784355393e-7 2.234409504043914e-6 1.2880959474039399e-6 2670/1080/10013/7316/3920/3320/6233/3326/7311/7431/3312/7314 12 Human_metapneumovirus R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 17/1124 42/10654 4.311799201053136e-7 2.261867546993128e-6 1.3039250037083077e-6 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Human_metapneumovirus R-HSA-69242 S Phase 39/1124 161/10654 4.574806742658414e-7 2.3857869153575946e-6 1.375362238425686e-6 8454/11065/246184/7027/7321/207/8697/1027/6500/898/8881/7316/5422/9978/5753/890/1026/4609/51433/5715/2932/6502/10000/8243/9126/51529/7324/64682/29945/10393/208/6233/51434/51343/7311/6117/29882/7314/996 39 Human_metapneumovirus R-HSA-5688426 Deubiquitination 60/1124 297/10654 4.5865693526260706e-7 2.3857869153575946e-6 1.375362238425686e-6 6885/90865/7321/991/8737/10392/8767/4738/9817/57506/4303/91833/6478/1080/330/9101/4287/7706/8517/64750/7416/29086/7316/890/7417/4792/8678/2099/4609/23586/5715/64127/329/6502/7347/4088/9146/64135/5728/10454/8473/7157/9929/4087/63891/7189/57599/6233/9804/7311/114548/7187/387/10318/60/7345/1540/7874/7314/4193 60 Human_metapneumovirus R-HSA-187687 Signalling to ERKs 15/1124 34/10654 5.436338615942544e-7 2.8159779106848824e-6 1.6233594281475644e-6 4893/5594/6714/1432/4914/4803/5603/2885/1398/3845/5600/3265/1399/6300/5595 15 Human_metapneumovirus R-HSA-110056 MAPK3 (ERK1) activation 8/1124 10/10654 5.554378874168107e-7 2.8532452473942396e-6 1.6448433617322455e-006 3717/3716/3570/7297/5781/3569/3572/5595 8 Human_metapneumovirus R-HSA-9020958 Interleukin-21 signaling 8/1124 10/10654 5.554378874168107e-7 2.8532452473942396e-6 1.6448433617322455e-006 3561/6775/6776/6774/3718/6772/3716/6777 8 Human_metapneumovirus R-HSA-205043 NRIF signals cell death from the nucleus 10/1124 16/10654 7.252461443391717e-7 3.710143498726837e-6 2.138829429586596e-6 4804/8878/23385/7316/4803/7189/6233/7311/5599/7314 10 Human_metapneumovirus R-HSA-418597 G alpha (z) signalling events 18/1124 48/10654 7.641087771396505e-7 3.8928669386785485e-6 2.244166129091111e-6 2788/54331/59345/10681/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 18 Human_metapneumovirus R-HSA-8949215 Mitochondrial calcium ion transport 12/1124 23/10654 8.018044620635084e-7 4.068171819814031e-6 2.3452261660011162e-6 10730/11331/8165/7416/7417/6687/30968/3954/221154/10367/10939/5245 12 Human_metapneumovirus R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 13/1124 27/10654 9.111276035543125e-7 4.603983564082607e-6 2.654111773189361e-6 23643/842/8737/355/841/7099/836/929/8772/353376/26060/8743/148022 13 Human_metapneumovirus R-HSA-6806834 Signaling by MET 24/1124 79/10654 1.0624781303905246e-6 5.3469427862742654e-6 3.0824140881676323e-6 5295/4893/5290/85440/5747/9101/7316/6774/4233/6714/867/9146/3914/6233/2885/1398/7311/3845/3265/1399/5781/53916/7314/5879 24 Human_metapneumovirus R-HSA-177929 Signaling by EGFR 18/1124 49/10654 1.0897518099703723e-6 5.461994901794821e-6 3.1487395148515337e-6 5295/4893/5290/5335/7316/6714/867/9146/1445/998/6233/2885/7311/1956/3845/3265/5781/7314 18 Human_metapneumovirus R-HSA-69052 Switching of origins to a post-replicative state 26/1124 90/10654 1.1229238253249053e-6 5.6055632893235195e-6 3.231504047412079e-6 8454/11065/246184/7321/8697/6500/898/8881/7316/9978/890/51433/5715/6502/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/7314/996 26 Human_metapneumovirus R-HSA-167044 Signalling to RAS 11/1124 20/10654 1.1726408580836108e-6 5.830238483162691e-6 3.3610251607723025e-6 4893/6714/1432/4914/4803/5603/2885/3845/5600/3265/6300 11 Human_metapneumovirus R-HSA-1428517 The citric acid (TCA) cycle and respiratory electron transport 40/1124 174/10654 1.3912823029028688e-6 6.8896299639750065e-6 3.971744847865874e-6 51300/9377/4967/4722/4723/4702/5160/7388/1743/4719/55863/4704/2109/4200/1737/51295/4729/7386/7416/6389/6341/7385/4728/4725/682/5162/27089/2108/3029/4726/7384/1738/51204/6834/4698/1340/1327/4697/4720/51079 40 Human_metapneumovirus R-HSA-111885 Opioid Signalling 26/1124 91/10654 1.4167773099038882e-6 6.987929520561807e-6 4.028412732710573e-6 2788/54331/59345/5594/10681/51764/94235/5528/55970/2792/5519/2793/2785/2783/2784/2782/2786/1385/5518/801/1020/2791/2790/5515/2787/5516 26 Human_metapneumovirus R-HSA-6783589 Interleukin-6 family signaling 12/1124 24/10654 1.4499448282061118e-6 7.094986945925559e-6 4.090129367687721e-6 9021/6774/6772/867/3717/3716/3570/5008/7297/5781/3569/3572 12 Human_metapneumovirus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 12/1124 24/10654 1.4499448282061118e-6 7.094986945925559e-6 4.090129367687721e-6 596/2309/5747/207/5594/1027/10000/208/7514/1385/1956/5595 12 Human_metapneumovirus R-HSA-163685 Integration of energy metabolism 29/1124 108/10654 1.462100007626187e-6 7.126298462367006e-6 4.10817988052447e-6 2788/54331/59345/10681/51764/94235/4082/5528/55970/2778/2792/5519/2793/2785/2783/2784/2782/3630/2786/9370/948/6844/5518/31/2791/2790/5515/2787/5516 29 Human_metapneumovirus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 14/1124 32/10654 1.4778586074988373e-6 7.17485865130808e-6 4.136173935538541e-6 57154/10273/4738/64750/7316/23327/867/4088/9040/4087/6233/7514/7311/7314 14 Human_metapneumovirus R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 10/1124 17/10654 1.5945602554049043e-6 7.711193735122154e-6 4.445361238340975e-6 23643/8737/355/841/7099/929/8772/353376/8743/148022 10 Human_metapneumovirus R-HSA-9614085 FOXO-mediated transcription 21/1124 65/10654 1.6363310340935665e-6 7.882403969680293e-6 4.5440607868746175e-6 2308/857/2309/10018/7532/207/10971/4303/1027/7295/4287/114907/1026/84676/4088/10000/3630/4087/56729/208/23411 21 Human_metapneumovirus R-HSA-9614399 Regulation of localization of FOXO transcription factors 8/1124 11/10654 1.8472934459950034e-6 8.864144519929512e-6 5.110016141920082e-6 2308/2309/7532/207/10971/4303/10000/208 8 Human_metapneumovirus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 12/1124 25/10654 2.521339285972133e-6 1.2005453984744233e-5 6.9209232222231015e-6 1849/5594/5528/5519/1432/1385/5518/6197/5600/5595/5515/5516 12 Human_metapneumovirus R-HSA-8854691 Interleukin-20 family signaling 12/1124 25/10654 2.521339285972133e-6 1.2005453984744233e-5 6.9209232222231015e-6 6775/6776/6774/3718/6772/3717/3716/282618/6777/6773/7297/5781 12 Human_metapneumovirus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 22/1124 72/10654 2.667301550923835e-6 1.2603508855128655e-5 7.265690845827079e-6 11065/246184/7321/991/8697/8881/7316/51433/5715/6502/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/7314/996 22 Human_metapneumovirus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 22/1124 72/10654 2.667301550923835e-6 1.2603508855128655e-5 7.265690845827079e-6 11065/246184/7321/8697/898/8881/7316/890/51433/5715/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/7314/996 22 Human_metapneumovirus R-HSA-445717 Aquaporin-mediated transport 18/1124 52/10654 2.9569016468425787e-6 1.3918799387038451e-5 8.0239316252122e-6 2788/54331/59345/10681/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 18 Human_metapneumovirus R-HSA-5654738 Signaling by FGFR2 22/1124 73/10654 3.4426771330814927e-6 1.6144069283162456e-5 9.306758756894942e-6 5295/4893/5290/5335/5430/5594/10817/7316/6714/867/5437/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 22 Human_metapneumovirus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 24/1124 84/10654 3.574804846328627e-6 1.670040905567864e-5 9.627478394481862e-6 9318/7336/8450/54778/7316/9978/64708/10980/10920/142/10987/7329/6233/2873/2968/7311/60/8533/6117/7334/50813/7314/51138/8451 24 Human_metapneumovirus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 20/1124 63/10654 3.919171309307301e-6 1.824035368767834e-5 1.0515228127069052e-5 11065/246184/7321/8697/8881/7316/51433/5715/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/7314/996 20 Human_metapneumovirus R-HSA-6804758 Regulation of TP53 Activity through Acetylation 13/1124 30/10654 4.0161990323974216e-6 1.862192659965546e-5 1.0735197886715757e-5 23774/64769/7862/207/84289/27154/10000/7994/7157/5371/208/5300/5608 13 Human_metapneumovirus R-HSA-198753 ERK/MAPK targets 11/1124 22/10654 4.031796367588892e-6 1.862449217565317e-5 1.0736676894050544e-5 1849/5594/5528/5519/1432/5518/6197/5600/5595/5515/5516 11 Human_metapneumovirus R-HSA-844456 The NLRP3 inflammasome 9/1124 15/10654 4.353852904127313e-6 2.0037434555054323e-5 1.1551212165910068e-5 834/351/4790/10910/7295/5970/3326/114548/4791 9 Human_metapneumovirus R-HSA-9006936 Signaling by TGF-beta family members 27/1124 102/10654 4.493191664263997e-6 2.0602115853180846e-5 1.187674053945805e-5 57154/5590/892/7027/7321/6497/10273/4738/64750/7323/54778/7316/6667/4609/23327/867/4088/142/9040/4087/6233/7514/1025/7311/387/4091/7314 27 Human_metapneumovirus R-HSA-210990 PECAM1 interactions 8/1124 12/10654 5.02737864218779e-6 2.2889466879106567e-5 1.3195356299663508e-5 5777/5335/6714/4067/2534/7525/3932/5781 8 Human_metapneumovirus R-HSA-109704 PI3K Cascade 16/1124 44/10654 5.0290266487213135e-6 2.2889466879106567e-5 1.3195356299663508e-5 5295/54106/5170/5290/3667/5291/2322/57761/5140/2261/208/2885/8660/5296/117145/5781 16 Human_metapneumovirus R-HSA-8878166 Transcriptional regulation by RUNX2 30/1124 121/10654 5.7717328366305595e-6 2.617364561080085e-5 1.5088624882342468e-5 8454/57154/25/10273/207/5594/6500/10013/7316/9978/865/11059/1026/10413/6772/6714/2099/5715/2932/6502/10000/55294/861/208/6233/7525/7311/4091/7314/5595 30 Human_metapneumovirus R-HSA-877300 Interferon gamma signaling 25/1124 92/10654 6.072732510795506e-6 2.7438112585273126e-5 1.5817566816440082e-5 3665/3460/5777/6737/960/9021/85363/9830/3383/7706/3662/3122/3663/3113/6772/8651/3659/3459/3717/3458/3661/5371/3716/81603/5781 25 Human_metapneumovirus R-HSA-1296065 Inwardly rectifying K+ channels 13/1124 31/10654 6.252185294943084e-6 2.8044222446157747e-5 1.6166977993788754e-5 2788/54331/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 13 Human_metapneumovirus R-HSA-5654733 Negative regulation of FGFR4 signaling 13/1124 31/10654 6.252185294943084e-6 2.8044222446157747e-5 1.6166977993788754e-5 5594/7316/6714/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 13 Human_metapneumovirus R-HSA-3858494 Beta-catenin independent WNT signaling 34/1124 146/10654 6.279318519590145e-6 2.8064246668781945e-5 1.6178521589519734e-5 2788/57154/1173/54331/6885/1499/59345/10681/51764/94235/64750/7316/55970/5216/2792/5715/2793/2785/2783/2784/2782/2786/6233/163/7311/387/4343/3845/801/2791/7314/5879/2790/2787 34 Human_metapneumovirus R-HSA-6807070 PTEN Regulation 33/1124 140/10654 6.500082792061861e-6 2.894641185817476e-5 1.6687073582044457e-5 3725/5468/1822/23186/10273/207/6045/5594/7316/4734/64223/10014/5715/10000/23512/5728/6009/6615/7157/23028/5371/208/6233/2475/7311/1386/4343/648/7874/57521/23608/7314/5595 33 Human_metapneumovirus R-HSA-163200 Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 30/1124 123/10654 8.218085624660794e-6 3.6465913990430335e-5 2.1021928140049115e-5 51300/9377/4722/4723/4702/7388/4719/55863/4704/2109/51295/4729/7386/6389/6341/7385/4728/4725/27089/2108/4726/7384/51204/6834/4698/1340/1327/4697/4720/51079 30 Human_metapneumovirus R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 9/1124 16/10654 9.019204452426368e-6 3.987776825751373e-5 2.2988799318590514e-5 5295/5170/5290/5291/6850/4067/2534/2885/5296 9 Human_metapneumovirus R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 19/1124 61/10654 9.305425703785055e-6 4.0996857726996076e-5 2.363393379721396e-5 25/5747/4690/4771/5594/4644/6850/3320/998/695/2885/1398/7410/10096/3326/7409/60/5879/5595 19 Human_metapneumovirus R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 13/1124 32/10654 9.518829870562883e-6 4.1788338226088115e-5 2.4090207735131144e-5 5295/5777/4690/5336/6850/4067/2534/695/2885/7409/5293/118788/801 13 Human_metapneumovirus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 21/1124 72/10654 1.0106126945658646e-5 4.420984155026644e-5 2.5486159825763663e-5 11065/246184/7321/991/8697/8881/7316/890/51433/5715/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 21 Human_metapneumovirus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 20/1124 67/10654 1.1153524562366956e-5 4.861994157820525e-5 2.8028501309432154e-5 11065/246184/7321/991/8697/8881/7316/51433/5715/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 20 Human_metapneumovirus R-HSA-8876384 Listeria monocytogenes entry into host cells 10/1124 20/10654 1.1246567882072145e-5 4.885351241405374e-5 2.8163150596657115e-5 1499/7316/4233/6714/867/9146/6233/2885/7311/7314 10 Human_metapneumovirus R-HSA-422356 Regulation of insulin secretion 22/1124 78/10654 1.134750490802741e-5 4.9119619147335433e-5 2.8316556229821803e-5 2788/54331/59345/10681/51764/94235/4082/55970/2778/2792/2793/2785/2783/2784/2782/3630/2786/948/6844/2791/2790/2787 22 Human_metapneumovirus R-HSA-171007 p38MAPK events 8/1124 13/10654 1.1859212864085715e-5 5.097814418659068e-5 2.938796170266855e-5 4893/6714/1432/5603/3845/5600/3265/6300 8 Human_metapneumovirus R-HSA-202670 ERKs are inactivated 8/1124 13/10654 1.1859212864085715e-5 5.097814418659068e-5 2.938796170266855e-5 1849/5594/5528/5519/5518/5595/5515/5516 8 Human_metapneumovirus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 21/1124 73/10654 1.2797135523814736e-5 5.436067825800951e-5 3.133793032814424e-5 11065/246184/7321/991/8697/8881/7316/890/51433/5715/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 21 Human_metapneumovirus R-HSA-450341 Activation of the AP-1 family of transcription factors 7/1124 10/10654 1.2865653254924705e-5 5.436067825800951e-5 3.133793032814424e-5 3725/5594/1432/1386/5599/5600/5595 7 Human_metapneumovirus R-HSA-74749 Signal attenuation 7/1124 10/10654 1.2865653254924705e-5 5.436067825800951e-5 3.133793032814424e-5 3643/3667/5594/3630/2885/8660/5595 7 Human_metapneumovirus R-HSA-8853334 Signaling by FGFR3 fusions in cancer 7/1124 10/10654 1.2865653254924705e-5 5.436067825800951e-5 3.133793032814424e-5 5295/4893/5290/2261/2885/3845/3265 7 Human_metapneumovirus R-HSA-8877330 RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) 7/1124 10/10654 1.2865653254924705e-5 5.436067825800951e-5 3.133793032814424e-5 865/3558/50943/3458/861/3559/1493 7 Human_metapneumovirus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 16/1124 47/10654 1.3357134253919989e-5 5.567721281600319e-5 3.209688826566632e-5 4893/5594/6714/3717/2244/1445/5894/2266/2243/60/3845/3265/369/801/5245/5595 16 Human_metapneumovirus R-HSA-6802949 Signaling by RAS mutants 16/1124 47/10654 1.3357134253919989e-5 5.567721281600319e-5 3.209688826566632e-5 4893/5594/6714/3717/2244/1445/5894/2266/2243/60/3845/3265/369/801/5245/5595 16 Human_metapneumovirus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 16/1124 47/10654 1.3357134253919989e-5 5.567721281600319e-5 3.209688826566632e-5 4893/5594/6714/3717/2244/1445/5894/2266/2243/60/3845/3265/369/801/5245/5595 16 Human_metapneumovirus R-HSA-9649948 Signaling downstream of RAS mutants 16/1124 47/10654 1.3357134253919989e-5 5.567721281600319e-5 3.209688826566632e-5 4893/5594/6714/3717/2244/1445/5894/2266/2243/60/3845/3265/369/801/5245/5595 16 Human_metapneumovirus R-HSA-5654726 Negative regulation of FGFR1 signaling 13/1124 33/10654 1.4198785669277868e-5 5.8986901538812076e-5 3.400486288862732e-5 5594/7316/6714/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 13 Human_metapneumovirus R-HSA-8856828 Clathrin-mediated endocytosis 33/1124 146/10654 1.6670967088693924e-5 6.902560955118088e-5 3.979199326222313e-5 9318/1173/23396/4738/1601/1785/1080/338/7316/64708/26052/10980/867/9146/10920/10987/29979/6233/2885/2873/10096/6844/163/7311/3575/1759/1956/60/8533/3312/50813/7314/51138 33 Human_metapneumovirus R-HSA-9034015 Signaling by NTRK3 (TRKC) 9/1124 17/10654 1.7371929174075474e-5 7.168816105835147e-5 4.132690519306375e-5 5295/4893/5290/3667/5335/6714/2885/3845/3265 9 Human_metapneumovirus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 22/1124 80/10654 1.7644742495889244e-5 7.257206382030194e-5 4.1836458864182224e-5 5335/2316/7706/7316/4734/6772/23586/6059/3661/7324/9246/51191/4599/6233/3716/7311/7318/5610/5300/7334/7314/5595 22 Human_metapneumovirus R-HSA-73893 DNA Damage Bypass 16/1124 48/10654 1.8093678606491524e-5 7.417209971800167e-5 4.275885010526753e-5 7320/7706/8450/7316/9978/10459/25898/7398/9246/57599/6233/7311/7318/6117/7314/8451 16 Human_metapneumovirus R-HSA-5218921 VEGFR2 mediated cell proliferation 10/1124 21/10654 1.944529454512297e-5 7.944975130977636e-5 4.5801319095339145e-5 5170/5590/4893/5335/7422/5921/6714/3845/3265/801 10 Human_metapneumovirus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 21/1124 75/10654 2.019268925621082e-5 8.223207006312171e-5 4.740527463888829e-5 11065/246184/7321/991/8697/8881/7316/890/51433/5715/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 21 Human_metapneumovirus R-HSA-5654727 Negative regulation of FGFR2 signaling 13/1124 34/10654 2.0783720852991807e-5 8.436146365902905e-5 4.8632830848415686e-5 5594/7316/6714/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 13 Human_metapneumovirus R-HSA-190236 Signaling by FGFR 23/1124 87/10654 2.3071617959483247e-5 9.33420360583015e-5 5.380996551953781e-5 5295/4893/5290/5335/5430/5594/10817/7316/6714/2261/867/5437/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 23 Human_metapneumovirus R-HSA-5696398 Nucleotide Excision Repair 27/1124 111/10654 2.4204693409477532e-5 9.760720013333286e-5 5.626875409437945e-5 9318/5430/7336/8450/54778/7316/9978/64708/10980/5437/10920/142/10987/7329/6233/2873/2968/7311/60/8533/6117/7334/7874/50813/7314/51138/8451 27 Human_metapneumovirus R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 8/1124 14/10654 2.5109093397345606e-5 1.005203358210488e-4 5.794812319247605e-5 4893/5921/5753/1398/387/3845/3265/5879 8 Human_metapneumovirus R-HSA-8983432 Interleukin-15 signaling 8/1124 14/10654 2.5109093397345606e-5 1.005203358210488e-4 5.794812319247605e-5 3561/6776/3560/6774/3718/2885/3716/6777 8 Human_metapneumovirus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 21/1124 76/10654 2.5170681829180235e-5 1.005203358210488e-4 5.794812319247605e-5 11065/246184/7321/991/8697/8881/7316/890/51433/5715/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 21 Human_metapneumovirus R-HSA-114452 Activation of BH3-only proteins 12/1124 30/10654 2.5378715267365952e-5 1.010252395530516e-4 5.823919089955699e-5 596/10018/7027/572/7532/207/10971/7533/10000/7157/208/5599 12 Human_metapneumovirus R-HSA-69618 Mitotic Spindle Checkpoint 27/1124 112/10654 2.8748158458448277e-5 1.1407121849858644e-4 6.575995760738169e-5 5905/11065/246184/5525/7321/991/5526/8697/8881/5528/51433/5519/1062/5529/51529/7324/64682/29945/10393/5527/51434/7514/5518/29882/996/5515/5516 27 Human_metapneumovirus R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 26/1124 106/10654 2.9148126951665366e-5 1.1528875771936652e-4 6.646184655533585e-5 9318/1173/4738/1601/1080/338/7316/64708/10980/867/9146/10920/10987/29979/6233/2885/2873/6844/163/7311/3575/1956/8533/50813/7314/51138 26 Human_metapneumovirus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 11/1124 26/10654 2.9621327183051238e-5 1.1678727086820837e-4 6.732571180056566e-5 57154/10273/64750/7316/23327/4088/4087/6233/7514/7311/7314 11 Human_metapneumovirus R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 9/1124 18/10654 3.14954702893882e-5 1.2339048170336263e-4 7.113234129315523e-5 5295/5290/9208/6776/6774/6772/2885/6777/7750 9 Human_metapneumovirus R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 9/1124 18/10654 3.14954702893882e-5 1.2339048170336263e-4 7.113234129315523e-5 4893/5594/2885/1385/1956/6197/3845/3265/5595 9 Human_metapneumovirus R-HSA-5655291 Signaling by FGFR4 in disease 7/1124 11/10654 3.214778292055169e-5 1.2554875474966244e-4 7.237654597421233e-5 5295/4893/5290/5335/2885/3845/3265 7 Human_metapneumovirus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 22/1124 83/10654 3.305271365633196e-5 1.284500441868831e-4 7.404908592696773e-5 8454/1147/8945/4893/4790/6885/5966/6500/8517/7316/5970/4792/8915/5715/23291/6233/7311/3845/3265/3551/801/7314 22 Human_metapneumovirus R-HSA-69239 Synthesis of DNA 28/1124 119/10654 3.309819393830025e-5 1.284500441868831e-4 7.404908592696773e-5 8454/11065/246184/7321/8697/6500/898/8881/7316/5422/9978/890/51433/5715/6502/51529/7324/64682/29945/10393/6233/51434/51343/7311/6117/29882/7314/996 28 Human_metapneumovirus R-HSA-1632852 Macroautophagy 24/1124 95/10654 3.488853148870509e-5 1.3497500619692783e-4 7.781060641230938e-5 8878/7249/10533/64419/7416/192111/7316/8678/6714/64223/56993/6009/55054/6233/2475/9804/7311/54543/55626/3312/5564/57521/7248/7314 24 Human_metapneumovirus R-HSA-1169408 ISG15 antiviral mechanism 20/1124 72/10654 3.5899834168528526e-5 1.3845481215152123e-4 7.981665048782534e-5 5335/7706/7316/4734/6772/23586/3661/7324/9246/51191/4599/6233/3716/7311/7318/5610/5300/7334/7314/5595 20 Human_metapneumovirus R-HSA-8943724 Regulation of PTEN gene transcription 18/1124 61/10654 3.6136120444635644e-5 1.389332829517358e-4 8.00924800963157e-5 3725/5468/1822/23186/6045/5594/64223/10014/23512/6009/6615/7157/23028/2475/1386/648/57521/5595 18 Human_metapneumovirus R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 12/1124 31/10654 3.745862893415959e-5 1.4357208241637636e-4 8.276666259527522e-5 857/1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 12 Human_metapneumovirus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 13/1124 36/10654 4.231130140908206e-5 1.6167096032235678e-4 9.320033253852385e-5 4893/5594/6714/2244/1445/5894/2266/2243/60/3845/3265/369/5595 13 Human_metapneumovirus R-HSA-69306 DNA Replication 29/1124 127/10654 4.364704006168879e-5 1.6626164798883301e-4 9.584677947149798e-5 8454/11065/246184/7321/8317/8697/6500/898/8881/7316/5422/9978/890/51433/5715/6502/51529/7324/64682/29945/10393/6233/51434/51343/7311/6117/29882/7314/996 29 Human_metapneumovirus R-HSA-354192 Integrin alphaIIb beta3 signaling 11/1124 27/10654 4.5247057984619583e-5 1.7130231738519584e-4 9.875263258835371e-5 5170/5747/207/6850/6714/2244/1445/2885/1398/2266/2243 11 Human_metapneumovirus R-HSA-9006921 Integrin signaling 11/1124 27/10654 4.5247057984619583e-5 1.7130231738519584e-4 9.875263258835371e-5 5170/5747/207/6850/6714/2244/1445/2885/1398/2266/2243 11 Human_metapneumovirus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 21/1124 79/10654 4.7364415400995824e-5 1.7877178739766106e-4 1.0305864455030541e-4 9318/5430/8450/7316/9978/64708/10980/5437/10920/10987/6233/2873/2968/7311/8533/6117/7874/50813/7314/51138/8451 21 Human_metapneumovirus R-HSA-111447 Activation of BAD and translocation to mitochondria 8/1124 15/10654 4.882936824673788e-5 1.8263068848779908e-4 1.0528322999296639e-4 596/572/7532/207/10971/7533/10000/208 8 Human_metapneumovirus R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 8/1124 15/10654 4.882936824673788e-5 1.8263068848779908e-4 1.0528322999296639e-4 6737/29110/7316/22954/3661/6233/7311/7314 8 Human_metapneumovirus R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 8/1124 15/10654 4.882936824673788e-5 1.8263068848779908e-4 1.0528322999296639e-4 7316/4233/867/9146/6233/2885/7311/7314 8 Human_metapneumovirus R-HSA-193704 p75 NTR receptor-mediated signalling 24/1124 97/10654 5.0263497083010505e-5 1.8742834153243074e-4 1.0804898865656664e-4 4804/4790/10018/572/8767/8878/23385/4615/7316/5970/4792/836/4803/3654/7189/6233/7410/7409/7311/387/5599/3551/7314/5879 24 Human_metapneumovirus R-HSA-447115 Interleukin-12 family signaling 17/1124 57/10654 5.0920363476172426e-5 1.8930753748799237e-4 1.0913231053214764e-4 3592/3593/6775/3595/3313/6774/6772/149233/3717/3458/998/3716/3594/51561/7297/3586/3572 17 Human_metapneumovirus R-HSA-112409 RAF-independent MAPK1/3 activation 10/1124 23/10654 5.174930257415573e-5 1.9181328319402632e-4 1.1057682680516099e-4 1849/5594/3717/3716/3570/7297/5781/3569/3572/5595 10 Human_metapneumovirus R-HSA-1251985 Nuclear signaling by ERBB4 12/1124 32/10654 5.422250837231749e-5 1.997841231099079e-4 1.1517186928706534e-4 2670/23118/51741/23385/348/6776/10413/6714/2099/3084/6285/6387 12 Human_metapneumovirus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 12/1124 32/10654 5.422250837231749e-5 1.997841231099079e-4 1.1517186928706534e-4 892/7027/54778/7316/6667/4609/4088/4087/6233/1025/7311/7314 12 Human_metapneumovirus R-HSA-416482 G alpha (12/13) signalling events 21/1124 80/10654 5.794260406213533e-5 2.1285740008582653e-4 1.2270837280689597e-4 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/695/2786/7410/7409/387/2791/2790/2787 21 Human_metapneumovirus R-HSA-2559585 Oncogene Induced Senescence 12/1124 33/10654 7.70932070597683e-5 2.8237097733725783e-4 1.627816704656584e-4 7027/5594/7316/6667/1031/7157/6233/7311/4343/7314/5595/4193 12 Human_metapneumovirus R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 10/1124 24/10654 8.036839003737581e-5 2.9349872231938427e-4 1.691966106050017e-4 5590/5594/6280/6279/1432/5300/5600/1536/5879/5595 10 Human_metapneumovirus R-HSA-5696395 Formation of Incision Complex in GG-NER 14/1124 43/10654 8.064334599880547e-5 2.936366539603564e-4 1.6927612565693532e-4 7336/8450/54778/7316/9978/142/7329/6233/2968/7311/6117/7334/7314/8451 14 Human_metapneumovirus R-HSA-5655302 Signaling by FGFR1 in disease 13/1124 38/10654 8.108191373291917e-5 2.943677689189265e-4 1.6969759997196847e-4 5295/4893/5290/5335/9208/6776/6774/6772/2885/3845/6777/3265/7750 13 Human_metapneumovirus R-HSA-8949664 Processing of SMDT1 8/1124 16/10654 8.863953204104957e-5 3.2086473879186945e-4 1.8497261533958635e-4 10730/11331/6687/30968/221154/10367/10939/5245 8 Human_metapneumovirus R-HSA-6802957 Oncogenic MAPK signaling 19/1124 71/10654 9.735603252407411e-5 3.513899949411188e-4 2.0256986359159813e-4 4893/10018/55750/5594/10533/6714/3717/2244/1445/5894/2266/2243/60/3845/3265/369/801/5245/5595 19 Human_metapneumovirus R-HSA-5205647 Mitophagy 11/1124 29/10654 9.840665935614281e-5 3.541495473340256e-4 2.0416069474744439e-4 8878/7416/192111/7316/6714/56993/6233/9804/7311/54543/7314 11 Human_metapneumovirus R-HSA-69620 Cell Cycle Checkpoints 52/1124 293/10654 1.0994369150561308e-4 3.9130892594676955e-4 2.2558239247675346e-4 5905/11065/246184/5525/7321/991/5526/7532/8317/10971/8697/1027/898/7533/11200/545/472/7336/8881/29086/5528/7316/890/1026/51433/5715/5519/1062/5529/7157/51529/7324/64682/29945/10393/8924/6233/5527/51434/7514/7158/7311/5518/6117/29882/7334/51230/7314/996/4193/5515/5516 52 Human_metapneumovirus R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 13/1124 39/10654 1.0999637013689483e-4 3.9130892594676955e-4 2.2558239247675346e-4 26224/898/10517/6774/26272/26270/55294/26190/7157/6468/54461/26234/84261 13 Human_metapneumovirus R-HSA-977444 GABA B receptor activation 13/1124 39/10654 1.0999637013689483e-4 3.9130892594676955e-4 2.2558239247675346e-4 2788/54331/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 13 Human_metapneumovirus R-HSA-991365 Activation of GABAB receptors 13/1124 39/10654 1.0999637013689483e-4 3.9130892594676955e-4 2.2558239247675346e-4 2788/54331/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 13 Human_metapneumovirus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 19/1124 72/10654 1.1938749985908098e-4 4.235006441992615e-4 2.4414032545455253e-4 6517/7532/207/10971/57186/7533/4644/7846/9847/208/6844/9882/4012/10383/60/5564/801/5879/57148 19 Human_metapneumovirus R-HSA-5654708 Downstream signaling of activated FGFR3 10/1124 25/10654 1.2136018477679263e-4 4.2926831072476933e-4 2.4746527903358014e-4 5295/4893/5290/5335/10817/2261/2885/3845/3265/5781 10 Human_metapneumovirus R-HSA-373752 Netrin-1 signaling 15/1124 50/10654 1.2962945324722366e-4 4.5721157584063506e-4 2.635740569849082e-4 5335/5747/4690/6478/6477/6714/1432/2534/5603/998/5599/5600/6300/5781/5879 15 Human_metapneumovirus R-HSA-1679131 Trafficking and processing of endosomal TLR 7/1124 13/10654 1.3808300763079866e-4 4.8564421433786573e-4 2.7996494968206184e-4 54106/10695/7184/7098/51311/81622/51284 7 Human_metapneumovirus R-HSA-1169091 Activation of NF-kappaB in B cells 18/1124 67/10654 1.3965880998149366e-4 4.884113185228507e-4 2.8156013430702555e-4 8454/1147/8945/4790/6885/5966/6500/8517/7316/5970/4792/8915/5715/23291/6233/7311/3551/7314 18 Human_metapneumovirus R-HSA-6802952 Signaling by BRAF and RAF fusions 18/1124 67/10654 1.3965880998149366e-4 4.884113185228507e-4 2.8156013430702555e-4 4893/10018/55750/5594/10533/6714/3717/2244/1445/5894/2266/2243/60/3845/3265/369/801/5595 18 Human_metapneumovirus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 11/1124 30/10654 1.406859954075397e-4 4.906176403226313e-4 2.8283203820996856e-4 7320/8450/7316/9978/7398/57599/6233/7311/6117/7314/8451 11 Human_metapneumovirus R-HSA-5621575 CD209 (DC-SIGN) signaling 9/1124 21/10654 1.41935373858815e-4 4.922016606084396e-4 2.837451967456186e-4 4893/4790/5970/4067/2534/5894/30835/3845/3265 9 Human_metapneumovirus R-HSA-6807004 Negative regulation of MET activity 9/1124 21/10654 1.41935373858815e-4 4.922016606084396e-4 2.837451967456186e-4 9101/7316/4233/867/9146/6233/2885/7311/7314 9 Human_metapneumovirus R-HSA-5674135 MAP2K and MAPK activation 13/1124 40/10654 1.4739040287488624e-4 5.096908345226513e-4 2.938273835612257e-4 4893/5594/6714/2244/1445/5894/2266/2243/60/3845/3265/369/5595 13 Human_metapneumovirus R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 8/1124 17/10654 1.519885123672486e-4 5.241275161856651e-4 3.021498647852061e-4 2308/857/2309/4303/1027/1026/4088/4087 8 Human_metapneumovirus R-HSA-453279 Mitotic G1-G1/S phases 31/1124 149/10654 1.5528319242224696e-4 5.340016450520604e-4 3.0784211831077026e-4 8454/25/7027/8317/207/1027/6500/898/7316/5422/5753/890/1026/6714/4609/1031/5715/5519/4067/3717/6502/10000/208/6233/7311/5518/6117/1859/7314/5515/5516 31 Human_metapneumovirus R-HSA-5689880 Ub-specific processing proteases 41/1124 220/10654 1.9731680776134252e-4 6.766709363117509e-4 3.9008833842306526e-4 6885/90865/991/8737/9817/4303/91833/6478/1080/330/9101/8517/64750/7416/7316/890/7417/4792/8678/4609/23586/5715/329/6502/4088/9146/64135/5728/10454/7157/4087/63891/7189/57599/6233/9804/7311/1540/7874/7314/4193 41 Human_metapneumovirus R-HSA-5205685 Pink/Parkin Mediated Mitophagy 9/1124 22/10654 2.1784379520433227e-4 7.450017084612247e-4 4.2947977071397867e-4 8878/7416/7316/56993/6233/9804/7311/54543/7314 9 Human_metapneumovirus R-HSA-195721 Signaling by WNT 56/1124 331/10654 2.2522247826436544e-4 7.681141269732353e-4 4.4280365452585113e-4 2788/8454/57154/8945/1173/857/54331/6885/1499/5525/59345/5526/207/6500/10681/51764/9101/94235/64750/8452/5528/7316/9978/55970/5216/2792/4609/5715/5519/2932/2793/2785/2783/2784/5529/2782/2786/208/6233/5527/7514/163/7311/5518/387/4343/25776/3845/801/2791/7314/5879/2790/5515/2787/5516 56 Human_metapneumovirus R-HSA-177504 Retrograde neurotrophin signalling 7/1124 14/10654 2.510569218642522e-4 8.538694210657808e-4 4.922400029611422e-4 1173/1785/26052/4914/4803/163/1759 7 Human_metapneumovirus R-HSA-195253 Degradation of beta-catenin by the destruction complex 20/1124 82/10654 2.560402534715627e-4 8.684324213638209e-4 5.006353045529042e-4 8454/8945/1499/5525/5526/6500/5528/7316/9978/5715/5519/2932/5529/6233/5527/7311/5518/7314/5515/5516 20 Human_metapneumovirus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 23/1124 102/10654 3.1778746126235425e-4 0.0010749204290786737 6.196718399076105e-4 8454/7124/1147/8945/23495/8744/8600/9039/6500/330/7316/9020/7133/5715/329/23291/9040/6233/7311/7187/958/4791/7314 23 Human_metapneumovirus R-HSA-2467813 Separation of Sister Chromatids 36/1124 190/10654 3.4032030862838773e-4 0.0011480014770625178 6.618017187725423e-4 5905/11065/246184/5525/7321/991/5526/8697/8881/5528/7316/51433/5715/5519/1062/7846/8243/9126/5529/51529/7324/64682/29945/10393/6233/5527/51434/7514/7311/5518/10383/29882/7314/996/5515/5516 36 Human_metapneumovirus R-HSA-2871809 FCERI mediated Ca+2 mobilization 11/1124 33/10654 3.7018953296134855e-4 0.0012453658744732323 7.179305015669173e-4 5335/5336/6850/4067/695/2885/7410/7006/7409/3702/801 11 Human_metapneumovirus R-HSA-6804760 Regulation of TP53 Activity through Methylation 8/1124 19/10654 3.895685434206426e-4 0.0013028669137675752 7.510787922238041e-4 11200/472/7316/7157/6233/7311/7314/4193 8 Human_metapneumovirus R-HSA-376172 DSCAM interactions 6/1124 11/10654 3.9359630512849204e-4 0.0013028669137675752 7.510787922238041e-4 1432/5603/5599/5600/6300/5879 6 Human_metapneumovirus R-HSA-4755510 SUMOylation of immune response proteins 6/1124 11/10654 3.9359630512849204e-4 0.0013028669137675752 7.510787922238041e-4 8517/5970/4792/7329/9641/4791 6 Human_metapneumovirus R-HSA-8875555 MET activates RAP1 and RAC1 6/1124 11/10654 3.9359630512849204e-4 0.0013028669137675752 7.510787922238041e-4 85440/4233/2885/1398/1399/5879 6 Human_metapneumovirus R-HSA-9020956 Interleukin-27 signaling 6/1124 11/10654 3.9359630512849204e-4 0.0013028669137675752 7.510787922238041e-4 6774/6772/3717/3716/7297/3572 6 Human_metapneumovirus R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 6/1124 11/10654 3.9359630512849204e-4 0.0013028669137675752 7.510787922238041e-4 4893/10817/2885/3845/3265/5781 6 Human_metapneumovirus R-HSA-6799198 Complex I biogenesis 15/1124 55/10654 4.1347735592720073e-4 0.0013650265777009987 7.869126942277672e-4 51300/4722/4723/4702/4719/55863/4704/51295/4729/4728/4725/4726/4698/4720/51079 15 Human_metapneumovirus R-HSA-76009 Platelet Aggregation (Plug Formation) 12/1124 39/10654 4.669546952392172e-4 0.0015374731720908268 8.863249814450988e-4 5170/5747/207/6850/6714/4352/2244/1445/2885/1398/2266/2243 12 Human_metapneumovirus R-HSA-449836 Other interleukin signaling 9/1124 24/10654 4.711690878669715e-4 0.0015472342991493654 8.919520915086044e-4 1436/1435/1441/1440/836/6844/3716/282618/7297 9 Human_metapneumovirus R-HSA-4791275 Signaling by WNT in cancer 11/1124 34/10654 4.956766054690361e-4 0.0016234064485996476 9.358639334670188e-4 1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 11 Human_metapneumovirus R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 10/1124 29/10654 5.016543663095469e-4 0.0016386493548580976 9.446511883290453e-4 2308/2309/4303/4287/114907/84676/4088/3630/4087/56729 10 Human_metapneumovirus R-HSA-1236975 Antigen processing-Cross presentation 22/1124 99/10654 5.269626582304555e-4 0.001716788870761326 9.89697180831714e-4 23643/1147/6890/10333/7099/8517/4615/7316/7096/5715/929/114609/695/6233/948/4012/7311/7097/3551/1536/7314/4360 22 Human_metapneumovirus R-HSA-165159 mTOR signalling 12/1124 40/10654 6.039108205382137e-4 0.001962313899806584 0.0011312378403782535 207/84335/7249/6198/64223/6009/208/2475/1978/5564/57521/7248 12 Human_metapneumovirus R-HSA-1226099 Signaling by FGFR in disease 16/1124 63/10654 6.411110043926899e-4 0.0020777367105710735 0.0011977769660464143 5295/4893/5290/5335/5430/9208/6776/6774/6772/2261/5437/2885/3845/6777/3265/7750 16 Human_metapneumovirus R-HSA-1963640 GRB2 events in ERBB2 signaling 7/1124 16/10654 6.919577529095444e-4 0.0022192841919741343 0.001279376483426973 4893/2064/3084/2885/1956/3845/3265 7 Human_metapneumovirus R-HSA-1963642 PI3K events in ERBB2 signaling 7/1124 16/10654 6.919577529095444e-4 0.0022192841919741343 0.001279376483426973 5295/5290/2065/2064/3084/2885/1956 7 Human_metapneumovirus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 7/1124 16/10654 6.919577529095444e-4 0.0022192841919741343 0.001279376483426973 57154/5590/7316/6233/7311/387/7314 7 Human_metapneumovirus R-HSA-391160 Signal regulatory protein family interactions 7/1124 16/10654 6.919577529095444e-4 0.0022192841919741343 0.001279376483426973 5777/5747/653509/6714/2885/2185/5781 7 Human_metapneumovirus R-HSA-264870 Caspase-mediated cleavage of cytoskeletal proteins 6/1124 12/10654 7.170762613467228e-4 0.002282109027113735 0.0013155938443866271 2934/841/5339/836/6709/7431 6 Human_metapneumovirus R-HSA-5689877 Josephin domain DUBs 6/1124 12/10654 7.170762613467228e-4 0.002282109027113735 0.0013155938443866271 4287/7316/9929/6233/7311/7314 6 Human_metapneumovirus R-HSA-9634600 Regulation of glycolysis by fructose 2,6-bisphosphate metabolism 6/1124 12/10654 7.170762613467228e-4 0.002282109027113735 0.0013155938443866271 5528/5519/5208/5518/5515/5516 6 Human_metapneumovirus R-HSA-8853659 RET signaling 12/1124 41/10654 7.730247562758051e-4 0.0024538580724857606 0.0014146040074358862 5295/2674/5290/5335/5291/6714/8503/2885/8660/5293/5296/5781 12 Human_metapneumovirus R-HSA-1236974 ER-Phagosome pathway 19/1124 83/10654 8.429032601643983e-4 0.0026688343633849746 0.0015385338817915251 23643/1147/6890/10333/7099/8517/4615/7316/7096/5715/929/114609/695/6233/948/7311/7097/3551/7314 19 Human_metapneumovirus R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 11/1124 36/10654 8.542660729627217e-4 0.0026979117304281874 0.001555296448627082 25/5747/4690/5594/998/695/2885/10096/60/5879/5595 11 Human_metapneumovirus R-HSA-9008059 Interleukin-37 signaling 8/1124 21/10654 8.651739439008244e-4 0.002725407996308449 0.0015711475397475797 834/5777/27178/29110/6774/59307/4088/5781 8 Human_metapneumovirus R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 15/1124 59/10654 9.263718895293682e-4 0.002910782739181111 0.001678012666580047 7319/7321/7320/7336/5591/7323/7316/8915/7322/118424/7324/6233/7311/7334/7314 15 Human_metapneumovirus R-HSA-202733 Cell surface interactions at the vascular wall 27/1124 137/10654 9.734373073310642e-4 0.0030509250290528035 0.0017588021169099575 5295/5777/4893/857/5290/5335/960/5291/483/6401/3684/7010/2888/338/6714/4067/54210/682/2534/2885/7525/3932/5296/3687/3845/3265/5781 27 Human_metapneumovirus R-HSA-3928662 EPHB-mediated forward signaling 12/1124 42/10654 9.79930788629688e-4 0.003063521000817055 0.0017660634627616385 5747/5921/6714/4067/2534/998/7525/10096/387/60/3265/5879 12 Human_metapneumovirus R-HSA-68882 Mitotic Anaphase 36/1124 201/10654 0.0010103590557625406 0.0031506914635617764 0.001816315629874062 5905/11065/246184/5525/7321/991/5526/8697/8881/5528/7316/51433/5715/5519/1062/7846/8243/9126/5529/51529/7324/64682/29945/10393/6233/5527/51434/7514/7311/5518/10383/29882/7314/996/5515/5516 36 Human_metapneumovirus R-HSA-180292 GAB1 signalosome 7/1124 17/10654 0.001069936221289148 0.0033280930702411188 0.0019185843904629526 5295/5290/6714/1445/2885/1956/5781 7 Human_metapneumovirus R-HSA-2555396 Mitotic Metaphase and Anaphase 36/1124 202/10654 0.001108063599567035 0.0034380519705864395 0.001981973672355757 5905/11065/246184/5525/7321/991/5526/8697/8881/5528/7316/51433/5715/5519/1062/7846/8243/9126/5529/51529/7324/64682/29945/10393/6233/5527/51434/7514/7311/5518/10383/29882/7314/996/5515/5516 36 Human_metapneumovirus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 15/1124 60/10654 0.0011169492786281849 0.003456958017354232 0.001992872660289235 8454/1147/8945/9039/6500/7316/9020/5970/5715/23291/9040/6233/7311/4791/7314 15 Human_metapneumovirus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 19/1124 85/10654 0.0011444453451161987 0.0035332252799347976 0.002036839333216387 8454/7027/207/1027/6500/898/7316/5753/890/1026/4609/5715/6502/10000/208/6233/51343/7311/7314 19 Human_metapneumovirus R-HSA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 6/1124 13/10654 0.0012133561931032294 0.003727382052262526 0.0021487671383674796 7027/5422/5519/5518/5515/5516 6 Human_metapneumovirus R-HSA-879415 Advanced glycosylation endproduct receptor signaling 6/1124 13/10654 0.0012133561931032294 0.003727382052262526 0.0021487671383674796 351/5594/177/3146/6285/5595 6 Human_metapneumovirus R-HSA-1250196 SHC1 events in ERBB2 signaling 8/1124 22/10654 0.001235076886013104 0.0037660718839512873 0.002171071114122075 4893/2065/2064/3084/2885/1956/3845/3265 8 Human_metapneumovirus R-HSA-5655332 Signaling by FGFR3 in disease 8/1124 22/10654 0.001235076886013104 0.0037660718839512873 0.002171071114122075 5295/4893/5290/5335/2261/2885/3845/3265 8 Human_metapneumovirus R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 8/1124 22/10654 0.001235076886013104 0.0037660718839512873 0.002171071114122075 5295/4893/5290/5335/2261/2885/3845/3265 8 Human_metapneumovirus R-HSA-2682334 EPH-Ephrin signaling 20/1124 92/10654 0.001239317549195004 0.0037697177540624446 0.0021731728911268916 1173/5747/23385/4318/5921/10398/6714/4067/2534/998/7525/7410/10096/163/1759/387/60/3265/1969/5879 20 Human_metapneumovirus R-HSA-5654716 Downstream signaling of activated FGFR4 9/1124 27/10654 0.0012618202539651832 0.0038287585157080802 0.00220720880337563 5295/4893/5290/5335/10817/2885/3845/3265/5781 9 Human_metapneumovirus R-HSA-8939902 Regulation of RUNX2 expression and activity 17/1124 73/10654 0.0012679234326877858 0.0038378709282823444 0.0022124619414806814 8454/57154/10273/6500/7316/9978/865/11059/6772/2099/5715/2932/6502/55294/6233/7311/7314 17 Human_metapneumovirus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 11/1124 38/10654 0.0014047320021567248 0.004241605411390305 0.002445207438927495 3815/7422/51741/2064/348/1026/2099/4609/3329/7329/1956 11 Human_papillomavirus_type_16 R-HSA-3700989 Transcriptional Regulation by TP53 322/4644 365/10654 1.7245137331417344e-73 2.4194927675978533e-70 8.56811033729367e-71 6884/6875/834/5563/3725/9134/4436/83990/64769/5892/9156/57060/1763/7531/1459/79370/7486/6874/10971/9997/133383/9212/5982/27327/7295/7533/2810/55367/1460/11200/472/53632/79813/5431/7001/639/5435/5433/1869/28996/84289/1457/6790/25904/29117/4194/1647/5928/1432/1387/4683/56950/51499/2965/84126/8738/5439/192669/1107/8900/6873/5371/2475/672/55571/6881/2967/51616/5518/1386/55835/4513/4343/6117/11198/7159/57472/904/144455/85456/29883/51497/51230/637/83695/7296/7314/5515/1263/27166/23368/9377/23774/6118/2176/3622/7027/6446/7832/51422/7249/404672/898/117584/27244/7534/332/5438/5934/64065/1351/116028/890/10769/983/1643/8797/9656/5519/27154/5458/83860/57459/2821/2177/10000/5985/2877/900/7994/2068/54541/3066/7157/5984/1337/6233/1025/2353/604/63970/839/7029/10419/5325/50484/5600/6883/7936/6829/79733/26523/7874/317/2744/5608/5884/5810/57521/26155/26013/5875/25920/5170/80010/2963/5434/83667/1820/7862/1029/5457/9219/8445/7532/5436/1345/55240/204851/6878/4869/5931/4850/4292/580/11073/891/80196/54971/4331/5366/641/5111/1108/8148/2966/246175/2962/84883/6119/147923/3364/5571/10524/54457/4848/8812/144715/23019/1616/843/6794/54815/94241/1874/10128/6009/905/1111/2071/55215/8626/208/79109/7311/7161/5562/6880/6908/5983/4697/5564/6882/5565/1020/53615/10397/8795/5432/665/7248/6877/7529/5516/1017/27161/27113/9891/6917/5440/27165/5305/8621/902/5883/25946/9540/5430/10111/8793/207/22974/57690/835/4849/1027/58484/3486/355/6749/545/5441/8794/192670/8550/7469/9337/7316/6872/2539/1026/54205/5933/124446/5395/6879/9150/112858/5876/143686/10848/5437/1350/9099/28984/51755/2033/995/5728/3065/91875/6827/23112/10498/10542/5527/2968/1349/5932/8851/5300/7156/581/1327/3276/5052/138474/133746/1022/8178/10919/4193 322 Human_papillomavirus_type_16 R-HSA-5663205 Infectious disease 328/4644 383/10654 1.1826688384208515e-67 8.296421901522273e-65 2.9379983775507474e-65 3839/6158/6884/23165/6875/5689/6138/2237/6227/7852/6206/6234/6191/162/6128/5682/6132/6129/27243/6874/6176/1174/811/6224/6146/348995/6154/143471/6202/57122/5705/3981/6169/5431/23511/5435/5709/6175/9978/5433/6218/5695/2960/292/567/6173/23279/5605/6167/5711/23327/29082/23225/5683/2965/2534/6156/5699/6143/5439/5702/6456/6873/3836/6139/30011/2885/163/9972/6881/2967/51616/3921/8021/7040/11198/904/55690/51497/5062/55746/6208/5696/6170/5691/7296/7314/5879/5718/3303/8945/6203/51606/1839/161/402569/5606/6147/25978/5700/122706/5707/2959/8027/10053/6222/2060/7518/8106/23198/404672/9636/10015/5438/6134/3978/10762/6155/1500/51534/4836/926/9397/6714/6231/9861/79902/6142/9883/23521/83860/51510/999/5698/9146/6455/5692/5713/5710/2068/5902/6207/5478/5719/6233/6844/7514/1025/3932/1213/5610/1211/6188/6396/129401/6883/7936/1175/6829/801/5608/8907/6122/2957/940/805/25920/6230/1173/4928/2963/3838/5434/5903/6857/6194/55706/7175/6166/1938/5436/6136/6878/6125/4869/821/5706/6232/160/6160/6616/920/4233/4331/5714/6193/6210/4927/6229/8148/6205/2966/2962/10898/3840/5688/54457/8812/5687/5708/128866/140801/6235/905/6181/2071/5901/8086/5704/3326/7311/6223/25873/6880/6908/7251/8905/5694/3304/1104/2547/9045/6882/2961/6187/6416/5432/6168/22916/1234/6157/6137/6877/5905/6144/3837/6917/81929/5440/164/5684/9349/8065/4736/5720/902/79872/51121/9631/5604/1499/3159/6159/6217/3843/5430/6152/5690/7520/5717/9491/6500/127833/6749/51065/6141/79023/5441/23636/10197/7469/919/6164/4686/7316/10213/6872/53371/3055/6209/9688/11224/6130/6879/9150/5715/9525/6204/5701/867/6228/5437/5685/3320/8815/5686/6124/6827/5609/2968/5716/9844/6189/808/6135/6201/375/6161/138474/1022/5693/10254/5721/6457/8178/8480/6133/291 328 Human_papillomavirus_type_16 R-HSA-449147 Signaling by Interleukins 370/4644 461/10654 4.832852440202768e-61 2.2601639912014946e-58 8.00388193605511e-59 5295/729230/8454/3605/7124/2308/834/1052/5689/3725/7291/5777/9252/1437/4790/5682/5291/26469/5657/5783/27178/356/3593/246/9021/8878/6624/5908/3082/5743/3091/941/1265/143471/10538/3383/5705/11009/6097/6349/6657/3576/3313/3662/6776/3688/4985/5709/6175/9978/2920/5695/84868/1435/4792/7133/3606/4609/3603/5711/4988/1432/3558/3717/4088/836/5683/2534/5699/3181/5702/4001/3654/3563/2885/85480/8660/6196/3594/1154/9846/6347/5518/1386/6382/9235/7040/3588/6197/4282/7334/3600/3312/1399/3551/3569/5062/5696/5691/51231/4692/7314/3572/3596/5515/257397/3598/5718/8945/1326/5601/1072/3592/5290/3667/6627/5606/90865/64109/9049/11213/3587/7412/5700/122706/5707/27250/8767/1849/29110/5594/4582/23198/23118/6367/4312/9987/8517/6778/7534/6810/332/5528/4313/3565/3976/50615/3185/5970/5443/9261/3718/3627/8809/9861/149233/5519/5598/4208/3567/598/2247/5698/5692/5713/2335/595/6195/5710/3458/10454/7157/5478/5719/6233/7525/6844/7409/2353/604/3932/7076/302/552900/51561/3570/5600/6777/6773/7850/7297/5781/5608/4791/59067/3557/56300/9655/3562/351/6464/3566/6597/5782/6351/7184/9180/3589/6775/50616/3684/3595/821/4318/5706/3726/58480/301/4478/1438/53833/3581/6616/79155/6774/920/6850/1440/5714/6772/8651/7867/5566/64127/8503/1901/3552/2889/5688/79923/5687/4067/3636/5708/5602/29949/3656/57162/5771/998/6648/116379/7189/163702/112744/6654/5704/3716/84639/7311/2939/1270/6888/5293/2185/240/6655/6356/5008/5694/246778/6416/1234/3586/3554/829/5595/5516/1147/5778/1845/596/5055/5684/2208/5720/6885/2309/5604/4215/3561/3578/10392/207/5292/5451/7422/5690/3553/2625/1230/5717/2919/9491/6500/3568/25930/10197/4615/3597/2357/1436/7316/10213/3560/6352/4314/1441/4205/3055/1026/6348/4793/3146/6647/6364/5715/7132/5701/867/6950/23291/5685/3320/5686/4843/9466/6288/2002/942/6285/5609/1398/58985/5716/1385/53832/6363/3575/4507/6845/5896/5296/6935/3687/5599/7431/375/3574/3559/3162/57161/1278/4170/5693/3689/5721/3601/5724/5034 370 Human_papillomavirus_type_16 R-HSA-72163 mRNA Splicing - Major Pathway 178/4644 183/10654 9.425220670812183e-58 3.305896150287373e-55 1.1707116201640396e-55 8449/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/5431/9092/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/22938/988/23020/6631/3181/5439/1660/9410/6638/3312/10907/10291/26121/10262/53981/6432/10084/6430/51340/6627/6936/83443/11051/9129/9879/8106/51690/27238/55749/5438/85313/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/10236/10250/4670/51362/10465/55660/25949/23283/2521/3191/10285/6636/23524/10914/8175/84950/3188/56259/5725/1994/10450/7536/2963/6635/5434/220988/6632/10283/24148/100534599/23350/5436/10523/6428/27258/6637/55110/5093/6429/57819/10181/2962/10898/10569/23658/6434/9295/84844/51692/10421/11193/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/51691/10946/27339/5430/79869/11325/57703/3184/25804/29894/11017/51503/3178/5441/3183/10594/4686/8189/23398/10713/10978/5546/7307/5437/6629/10189/10949/51729/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/57461/84991/10992/55339/6628 178 Human_papillomavirus_type_16 R-HSA-453274 Mitotic G2-G2/M phases 188/4644 198/10654 1.4830433262052534e-55 4.1614195733319415e-53 1.4736767367765888e-53 114791/10844/8454/5689/440145/5682/7531/11190/203068/54801/51807/63943/51400/79441/143471/10381/5705/5116/5048/5709/9978/1869/5695/8655/6790/9702/5711/5928/7846/7840/5683/5699/11064/5702/5520/81027/8900/28227/5518/55835/29922/23332/7465/93323/5696/5691/7314/5515/5718/8945/79861/4659/5700/122706/5707/1454/23198/993/890/983/9861/79959/5519/5698/5692/5713/80097/10376/5710/10540/7157/85378/5719/6233/7514/54930/54820/1453/27229/9793/4218/5500/84617/2305/11258/22981/8636/51512/7532/84962/55125/10382/121441/7277/5706/9133/286826/9814/653784/23354/728642/891/9738/4331/1639/5714/55722/4957/5566/5688/5687/91750/7283/347733/5708/22919/984/10426/22994/79866/1069/5577/5704/3326/55957/7311/10133/10383/5347/84790/80184/5694/22897/5108/7280/10806/1778/5516/115106/1017/22822/22995/55559/5684/994/5720/4605/902/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/1781/7316/10213/80321/1026/10121/1871/5715/84131/9088/5701/23291/5685/3320/5686/2033/995/10733/4751/27175/80254/5716/9662/55142/1022/8481/5693/5721/132660/55755 188 Human_papillomavirus_type_16 R-HSA-69242 S Phase 159/4644 161/10654 4.1436686561016264e-55 9.689278540850971e-53 3.431248431017487e-53 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/10274/5925/143471/5705/5709/5422/9978/1869/4174/5753/5695/84515/4609/4998/5711/5928/5683/990/5699/5702/8900/51529/29945/51434/84296/157570/6117/29882/5001/10714/7465/5558/5696/5691/7314/996/5718/6118/23594/7027/5700/122706/5707/64785/23198/898/3978/91768/5934/5557/993/890/51433/9861/2932/6502/5698/10000/5692/5985/5713/119504/595/4175/5710/5984/7324/5719/64682/6233/7029/113130/23649/1163/5424/4999/4172/1019/5000/8318/246184/54107/4173/5706/286826/23047/8881/5885/4331/5425/5714/5111/6119/5688/5687/91750/5427/5708/1874/8243/81620/10393/208/5704/55957/51343/23595/7311/25906/51659/5983/5694/4176/56655/1017/5684/994/5720/902/57804/207/9837/5690/5717/1027/9491/6500/23244/10735/10197/4149/7316/10213/1875/1026/5426/4171/5715/5701/5685/5686/9126/5716/114799/5981/1022/5693/5721/132660 159 Human_papillomavirus_type_16 R-HSA-69275 G2/M Transition 186/4644 196/10654 7.360226573897015e-55 1.4751996975967874e-52 5.224100665984048e-53 114791/10844/8454/5689/440145/5682/7531/11190/203068/54801/51807/63943/51400/79441/143471/10381/5705/5116/5048/5709/9978/5695/8655/6790/9702/5711/5928/7846/7840/5683/5699/11064/5702/5520/81027/8900/28227/5518/55835/29922/23332/7465/93323/5696/5691/7314/5515/5718/8945/79861/4659/5700/122706/5707/1454/23198/993/890/983/9861/79959/5519/5698/5692/5713/80097/10376/5710/10540/7157/85378/5719/6233/7514/54930/54820/1453/27229/9793/4218/5500/84617/2305/11258/22981/8636/51512/7532/84962/55125/10382/121441/7277/5706/9133/286826/9814/653784/23354/728642/891/9738/4331/1639/5714/55722/4957/5566/5688/5687/91750/7283/347733/5708/22919/984/10426/22994/79866/1069/5577/5704/3326/55957/7311/10133/10383/5347/84790/80184/5694/22897/5108/7280/10806/1778/5516/115106/1017/22822/22995/55559/5684/994/5720/4605/902/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/1781/7316/10213/80321/1026/10121/5715/84131/9088/5701/23291/5685/3320/5686/2033/995/10733/4751/27175/80254/5716/9662/55142/1022/8481/5693/5721/132660/55755 186 Human_papillomavirus_type_16 R-HSA-9006925 Intracellular signaling by second messengers 262/4644 305/10654 1.440243065354321e-54 2.5258262758651402e-52 8.944667458516309e-53 5295/1912/2308/5689/374/3725/6591/2250/5335/5682/5291/1822/1459/5526/9112/817/6045/5578/7039/5582/27327/80012/3082/1460/941/143471/2064/5705/5709/5695/107/1457/1911/4734/11060/5711/5928/5683/145957/2534/23512/9965/57332/5699/2444/2264/3630/5702/192669/1107/3654/5371/9542/2885/2475/8660/5518/1386/2252/4343/2253/5696/814/5691/7314/5879/5515/5718/818/23396/1839/5290/3667/8823/90865/2065/23186/5700/3815/122706/5707/5567/2146/51564/5594/2069/84232/7249/23198/112/57761/2260/5573/5528/111/2249/6714/2099/9861/7101/2248/5519/2932/84733/57459/2247/5698/5880/10000/5692/5713/5710/3066/7157/5613/5719/6233/5580/7409/2246/2251/5154/3932/2931/331/8726/196883/8394/115/255324/26523/7874/801/5781/57521/23608/940/6015/805/5170/3838/23239/9219/8535/4303/5568/930/5931/5706/6199/113/2263/4233/8658/5714/10645/1108/2122/5566/84254/10014/8503/5688/5159/5687/29851/5708/3084/54815/6009/5529/816/7189/208/5577/5704/10718/79109/57504/7311/5293/1956/648/2549/5694/23466/53615/109/5595/5516/1147/8822/27161/815/5684/8841/685/5305/5720/2309/5468/5525/5575/842/5978/8870/10273/207/5690/57690/5717/1027/9491/8817/114/10197/108/192670/4615/2100/2254/7316/10213/1950/1026/10768/26281/57167/10818/5715/1958/2261/5701/5576/5685/2255/3164/5686/391/5728/6615/3065/2066/27006/23028/942/5987/23112/10542/5527/5716/1385/5155/4254/5296/5581/808/5693/5721/5137/5156/4193 262 Human_papillomavirus_type_16 R-HSA-913531 Interferon Signaling 187/4644 199/10654 3.2740628786407215e-53 5.1039002430365915e-51 1.8074358815420124e-51 80263/3839/3443/23165/5777/5335/960/5770/3107/817/9021/348995/3383/57122/55223/3662/3115/23511/4684/567/4734/6672/3113/23279/3106/8672/3459/3717/23225/3117/1973/11074/3836/5371/4599/684/9972/3133/3429/117854/8021/3127/91543/7334/4938/4261/55746/5696/7314/3445/818/402569/115362/7412/10410/85363/9830/163351/9636/3126/2634/3444/10762/2317/115361/103/3434/10475/3433/79902/23586/9883/3451/10437/3448/1981/10612/3458/3661/7324/1977/3439/51191/6233/5580/81603/10107/5610/10581/3452/4940/6396/3437/129401/6773/7297/5781/3430/3660/3446/8554/3135/3665/3120/4928/3838/5903/10379/55706/7175/3455/2316/2633/4600/3123/23650/2209/8638/25820/1982/7706/23087/9470/3122/3394/3663/6772/8651/4927/3659/3840/25939/2635/3440/5771/3454/816/8086/10346/9246/3716/7311/3125/7726/79097/3456/3105/1974/5595/3460/815/3837/81929/3441/6737/51447/9631/23321/4281/3119/4502/54739/79023/2537/23636/3449/51127/7316/53371/8519/3664/9688/6041/1958/4939/388646/7341/6059/55128/3669/3134/5300/9775/80128/5495/5724/8480 187 Human_papillomavirus_type_16 R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 219/4644 244/10654 5.191319403147716e-53 7.283421122616247e-51 2.5792660613533916e-51 8449/23165/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/348995/57122/5431/9092/23511/81608/5435/6625/5433/51645/3190/1477/9416/65109/56339/22826/23279/22938/988/23020/23225/6631/3181/5439/1660/9410/6638/57721/9877/9972/8021/3312/10907/10291/55746/26121/10262/53981/7919/6432/10084/6430/51340/56001/6627/6936/83443/11051/9129/9879/8106/51690/27238/55749/5438/85313/10762/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/79902/9883/10236/10250/4670/51362/10465/55660/25949/23283/2521/1977/3191/10285/6636/23524/10914/6396/129401/8175/2733/84950/3188/84324/56259/5725/1994/10450/7536/4928/2963/6635/5434/5903/220988/6632/10283/55706/7175/24148/100534599/7884/23350/5436/10523/6428/27258/10212/6637/55110/5093/6429/57819/10181/4927/2962/10898/10569/23658/6434/9295/84844/10482/51692/10421/11193/8086/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/81929/5440/55599/51691/10946/9631/27339/5430/79869/11325/57703/3184/25804/29894/9589/11017/51503/3178/79023/5441/23636/3183/10594/4686/8189/23398/10713/53371/10978/5546/7307/9688/9984/5437/6629/10189/10949/51729/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/57461/84991/8480/10992/55339/6628 219 Human_papillomavirus_type_16 R-HSA-453279 Mitotic G1-G1/S phases 148/4644 149/10654 9.51102377160032e-53 1.2130878501413862e-50 4.2958882489907663e-51 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/1031/4998/5711/5928/10926/3717/5683/990/5699/5702/5520/8900/55388/1032/28227/1030/5518/6117/5001/7465/5558/5696/5691/7314/5515/6241/5718/6118/25/23594/7027/5700/5707/7153/898/91768/5934/5557/993/890/1876/983/6714/9861/5519/6502/5698/10000/5692/5713/595/4175/5710/896/5719/6233/7298/7029/23649/1719/1163/1859/4999/4172/26271/1019/5000/8318/1029/54107/4173/5706/286826/891/4331/5714/5111/51053/6119/5688/5687/91750/5427/4067/5708/1874/81620/208/1870/5704/29935/55957/23595/7311/5694/4176/5516/56655/1017/894/5684/5720/4605/902/8317/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5933/5426/4171/1871/5715/5701/5685/5686/1021/3065/5716/1022/5693/5721/7083/132660/1028 148 Human_papillomavirus_type_16 R-HSA-68877 Mitotic Prometaphase 187/4644 200/10654 2.9017246378290755e-052 3.3925997223951606e-50 1.2014158149608104e-50 114791/10844/55839/11130/440145/6249/9735/7531/1459/11190/203068/5526/54801/51807/9212/10274/1460/147841/348995/79441/10381/57122/5116/1780/23122/5048/57405/8655/1457/23279/9702/2491/7846/7840/1060/11064/81027/11004/9184/5518/55835/29922/23332/25909/10726/81930/55746/93323/5515/79682/10403/79861/64151/25936/55869/1454/3619/64105/332/10051/5528/983/79902/3796/79959/5519/81565/80097/91687/11243/10376/23397/10540/85378/83540/7514/54930/54820/113130/6396/1453/27229/64946/9793/140735/220134/84617/4928/5903/11258/22981/55055/8636/80776/1783/401541/7532/55125/10382/79172/121441/7277/9133/79980/6232/23047/9814/653784/5885/23354/891/5501/9738/1639/55722/4957/5566/54821/9183/1062/699/7283/347733/22919/8243/10426/5529/22994/51143/1069/5577/10383/5347/84790/84643/80184/22897/5108/10592/7280/10806/1778/5516/115106/4926/5905/22995/55559/81929/54908/55143/5525/10142/1058/991/79019/348235/80152/1063/8379/95681/23244/23421/55920/79023/10735/1781/80321/4085/55166/10121/84131/3320/79003/9126/9918/10733/4751/5527/27175/80254/701/57551/9662/55142/8481/55755 187 Human_papillomavirus_type_16 R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 364/4644 473/10654 1.2909732180852036e-51 1.3932580192104158e-49 4.933921934706204e-50 5295/3675/374/5777/627/9252/4893/857/2250/2670/5335/71/5579/5770/5291/26469/256076/5578/7039/3249/1785/5908/3082/117/51741/23385/2064/535/1280/1289/54845/5431/8829/50617/6696/6776/5435/3688/10312/5433/5753/7423/4734/10413/5605/3910/1290/1432/3717/55824/145957/2534/9475/3690/9965/5439/2264/5603/3630/6456/83737/6868/4145/9542/30011/2885/2475/8660/6093/163/7073/6196/9846/1759/5518/8440/2252/8874/9564/2253/6197/3845/1285/3265/1399/3071/5062/4486/10252/51231/56034/5829/7314/5879/5515/6387/5607/54106/26999/51606/1839/3918/161/5290/3667/8823/2065/5340/3815/5567/8027/10006/1849/1284/2060/9114/5594/2069/284217/9101/23118/57761/5921/6778/2260/5438/348/5528/9306/1500/3185/11059/102/9261/2249/6714/2099/2248/1447/5519/5598/4208/4670/2567/4909/2247/4914/10810/10000/9146/6455/2335/64759/6195/3728/8471/1445/84951/3925/6233/7525/7410/5580/2324/7409/2246/23191/3685/1292/2251/5154/3932/1213/3791/1729/1211/29924/1293/1535/5600/6777/255324/1175/523/6300/801/5781/5663/5725/1302/1291/10787/805/25920/5170/1286/4908/1173/116/1287/2963/5434/5590/6464/80310/85440/5241/2904/6461/5747/5782/7424/5436/10019/10193/5568/2322/7074/3315/2241/10451/4318/382/1277/160/3912/1793/673/6774/2263/4233/10152/6772/8651/26052/7867/5566/5802/2962/1003/8503/5795/2889/10163/5159/4067/3084/55845/5063/5771/1111/5796/998/3481/2886/3913/208/6654/5867/10718/79109/5900/7311/2185/387/1956/60/2549/5058/1020/5432/3480/22916/11140/4916/7529/63916/5595/25759/5516/8822/1845/10253/9402/5440/1282/8065/685/26018/558/4915/1495/5604/1499/4690/1299/5430/10048/10273/207/7422/10458/3178/8817/5441/58513/2254/4686/7316/1950/9611/51072/9047/4205/5289/57498/1301/10768/26281/10818/1281/8936/23545/2261/867/5437/2255/53358/3320/4846/4803/2002/2066/3914/27006/6285/1742/1398/3187/5774/1385/9844/5228/5906/3479/5155/23163/4254/8851/5296/5581/581/808/10076/131873/7057/1278/10254/6457/5156/161742/9296/2887/2242 364 Human_papillomavirus_type_16 R-HSA-72172 mRNA Splicing 179/4644 191/10654 1.8038599551733545e-50 1.74119363674616e-48 6.166060671074672e-49 8449/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/5431/9092/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/22938/988/23020/6631/3181/5439/1660/9410/6638/3312/10907/10291/26121/10262/53981/6432/10084/6430/51340/6627/6936/83443/11051/9129/9879/8106/51690/27238/55749/5438/85313/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/10236/10250/4670/51362/10465/55660/25949/23283/2521/3191/10285/6636/23524/10914/8175/84950/3188/56259/5725/1994/10450/7536/2963/6635/5434/220988/6632/10283/24148/100534599/23350/5436/10523/6428/27258/6637/55110/5093/6429/57819/10181/2962/10898/10569/23658/6434/9295/84844/51692/10421/11193/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/55599/51691/10946/27339/5430/79869/11325/57703/3184/25804/29894/11017/51503/3178/5441/3183/10594/4686/8189/23398/10713/10978/5546/7307/5437/6629/10189/10949/51729/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/57461/84991/10992/55339/6628 179 Human_papillomavirus_type_16 R-HSA-2555396 Mitotic Metaphase and Anaphase 187/4644 202/10654 1.8615755203986032e-50 1.74119363674616e-48 6.166060671074672e-49 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/5520/81027/51529/4001/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/7444/5698/5692/5713/91687/119504/11243/10376/5710/7324/2010/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/26271/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/347733/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/7443/1781/7316/10213/4085/55166/5715/5701/5685/8815/5686/79003/9126/9232/5527/9700/5716/701/57551/5693/5721 187 Human_papillomavirus_type_16 R-HSA-2467813 Separation of Sister Chromatids 178/4644 190/10654 3.9621598387467367e-50 3.336043157229527e-48 1.1813875306391093e-48 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/81027/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/5698/5692/5713/91687/119504/11243/10376/5710/7324/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/347733/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7280/1778/5516/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/1781/7316/10213/4085/55166/5715/5701/5685/5686/79003/9126/9232/5527/9700/5716/701/57551/5693/5721 178 Human_papillomavirus_type_16 R-HSA-68882 Mitotic Anaphase 186/4644 201/10654 4.042247588945257e-50 3.336043157229527e-48 1.1813875306391093e-48 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/5520/81027/51529/4001/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/7444/5698/5692/5713/91687/119504/11243/10376/5710/7324/2010/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/347733/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/7443/1781/7316/10213/4085/55166/5715/5701/5685/8815/5686/79003/9126/9232/5527/9700/5716/701/57551/5693/5721 186 Human_papillomavirus_type_16 R-HSA-5663202 Diseases of signal transduction 301/4644 377/10654 1.1079687693604055e-48 8.636001018959161e-47 3.0582529774158564e-47 5295/8454/2308/27123/5689/374/4893/11052/2250/5335/71/79718/5682/5291/892/5526/817/1452/7039/9530/613/182/5908/3082/941/143471/23385/2064/5705/54845/5431/6776/5435/5709/9978/5433/5695/8546/9759/9612/5605/4609/4089/22938/5711/1387/3717/4088/6907/5683/145957/324/2534/3690/408/9965/5699/6400/8312/11064/5439/2264/5702/4296/5894/6868/9794/9542/2885/2475/8660/8826/9846/5518/2252/6469/4140/7040/2253/3845/3265/4763/5696/7750/5691/7314/5879/5515/5718/818/8805/1839/5290/3667/8823/79885/2065/2648/9734/55869/5700/3815/122706/5707/10956/8844/51564/7094/8322/55534/5594/3280/2069/7249/23198/84441/7414/10533/10013/23164/2260/5438/5528/83933/102/2249/6714/2099/9861/2248/5519/9061/8850/399687/2932/7046/2247/5698/5880/10000/5692/5713/2335/1445/5710/3066/5719/6233/7409/2246/2251/5154/3932/2931/6777/255324/369/801/5781/5663/940/1523/805/5170/2963/5434/7276/6464/142678/283455/3674/5436/4303/409/930/5706/6199/10046/9208/84447/673/6774/2263/4233/8658/1024/5714/6772/6934/10014/2962/8503/5688/5159/5687/29851/5708/3084/5529/816/4087/208/6654/5704/10718/79109/56829/7048/23493/7311/5293/1956/11160/60/2549/611/5694/4851/5432/22916/11140/7529/5595/5516/4000/1147/8822/27044/815/5440/5684/22906/8841/685/5720/8087/1487/2309/5604/1499/6017/10018/5525/10142/842/5430/23462/207/5690/5717/1027/9491/6500/8817/5441/10197/2100/2254/4686/7316/10213/1950/9611/1026/26281/10818/7415/5715/2261/5701/867/5437/5685/2255/3164/3320/5686/2033/54894/391/55294/5728/3065/2066/27006/942/5527/1488/5716/1385/5906/5155/4254/5296/808/3516/5693/5721/5245/5156/4193 301 Human_papillomavirus_type_16 R-HSA-69620 Cell Cycle Checkpoints 247/4644 293/10654 2.8850320052180793e-48 2.130368370168929e-46 7.544238816969161e-47 5689/55839/11130/9134/83990/11065/6249/5682/9156/57060/9735/1763/7531/7486/7321/5526/10971/8697/9212/5982/7533/2810/147841/348995/11200/143471/472/57122/5705/1780/23122/5048/5709/4174/5695/57405/8655/84515/23279/4194/4998/5711/2491/4683/10926/5683/990/1060/165918/84126/5699/5702/8900/51529/29945/8924/11004/51434/55388/672/9184/5518/6117/29882/7334/5001/23332/7465/25909/51230/10726/81930/55746/5696/83695/5691/7314/996/5515/5718/6118/79682/10403/23594/25936/5700/122706/5707/51588/51720/3619/23198/63967/898/64105/7534/332/5528/993/116028/890/983/51433/9861/79902/3796/9656/5519/81565/5698/5692/5985/5713/91687/119504/11243/4175/5710/7157/5984/7324/83540/5719/64682/6233/7514/7158/54820/6396/64946/9793/5884/5810/140735/4999/220134/4172/80010/4928/5903/5000/8318/246184/55055/51512/1029/80776/1783/401541/7532/79172/4173/5706/9133/79980/6232/580/8881/11073/891/5501/641/5714/54821/6119/9183/3364/10524/5688/1062/699/5687/144715/5708/22919/5529/51143/1111/10393/5704/23595/7311/25906/5347/84643/5983/5694/4176/7529/1778/5516/1017/5905/81929/5684/5720/54908/55143/5883/5525/25946/1058/991/79019/10111/8317/348235/80152/5690/1063/8379/5717/1027/9491/23421/545/55920/79023/10197/7336/29086/1781/7316/10213/4085/1026/4171/55166/5715/9088/7341/5701/5685/5686/995/79003/5527/5716/701/5932/9025/79184/57551/7156/5693/5721/4193 247 Human_papillomavirus_type_16 R-HSA-1257604 PIP3 activates AKT signaling 227/4644 264/10654 1.7596999390261338e-47 1.234429507226833e-45 4.371465111685975e-46 5295/1912/2308/5689/374/3725/6591/2250/5682/5291/1822/1459/5526/9112/6045/7039/27327/80012/3082/1460/941/143471/2064/5705/5709/5695/1457/1911/4734/11060/5711/5928/5683/145957/2534/23512/9965/57332/5699/2444/2264/3630/5702/192669/1107/3654/5371/9542/2885/2475/8660/5518/1386/2252/4343/2253/5696/5691/7314/5879/5515/5718/23396/1839/5290/3667/8823/90865/2065/23186/5700/3815/122706/5707/2146/51564/5594/2069/84232/7249/23198/57761/2260/5528/2249/6714/2099/9861/7101/2248/5519/2932/84733/57459/2247/5698/5880/10000/5692/5713/5710/3066/7157/5719/6233/7409/2246/2251/5154/3932/2931/331/8726/8394/255324/26523/7874/5781/57521/23608/940/6015/5170/23239/9219/8535/4303/930/5931/5706/6199/2263/4233/8658/5714/1108/2122/10014/8503/5688/5159/5687/29851/5708/3084/54815/6009/5529/7189/208/5704/10718/79109/57504/7311/5293/1956/648/2549/5694/23466/53615/5595/5516/1147/8822/27161/5684/8841/685/5305/5720/2309/5468/5525/842/5978/8870/10273/207/5690/57690/5717/1027/9491/8817/10197/192670/4615/2100/2254/7316/10213/1950/1026/26281/57167/10818/5715/1958/2261/5701/5685/2255/3164/5686/391/5728/6615/3065/2066/27006/23028/942/5987/23112/10542/5527/5716/1385/5155/4254/5296/5693/5721/5156/4193 227 Human_papillomavirus_type_16 R-HSA-69206 G1/S Transition 130/4644 131/10654 3.527327378369651e-46 2.356590624691724e-44 8.345356002959778e-45 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/4998/5711/5928/10926/5683/990/5699/5702/8900/55388/28227/5518/6117/5001/7465/5558/5696/5691/7314/5515/6241/5718/6118/23594/7027/5700/5707/898/91768/5934/5557/993/890/1876/983/9861/5519/6502/5698/10000/5692/5713/595/4175/5710/5719/6233/7298/7029/23649/1719/1163/4999/4172/26271/1019/5000/8318/54107/4173/5706/286826/891/4331/5714/5111/51053/6119/5688/5687/91750/5427/5708/1874/81620/208/5704/29935/55957/23595/7311/5694/4176/5516/56655/1017/5684/5720/902/8317/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5933/5426/4171/5715/5701/5685/5686/3065/5716/1022/5693/5721/7083/132660 130 Human_papillomavirus_type_16 R-HSA-68886 M Phase 308/4644 395/10654 8.789162602328951e-46 5.605088695939781e-44 1.9849209322006055e-44 114791/10844/23165/5689/55839/11130/11065/440145/6249/5579/5682/9735/7531/1459/11190/7321/91754/203068/5526/54801/51807/8697/5578/9212/10274/5861/5925/1460/147841/348995/79441/143471/10381/57122/5705/5116/1780/23122/23511/5048/5709/5695/57405/8655/1457/23279/9702/5711/2491/10112/7846/23225/7840/5683/1060/5699/9663/11064/5702/5520/81027/51529/4001/29945/11004/51434/9184/9972/5518/55844/55835/29922/8021/29882/23332/84930/25909/10726/81930/55746/93323/5696/5691/7314/996/5515/5718/79682/10403/79861/64151/25936/55869/5700/122706/5707/1454/2801/5594/3619/23198/64105/23310/332/10762/10051/5528/983/51433/9861/79902/3796/8615/79959/5519/9883/81565/2029/7444/5698/5692/5713/80097/91687/119504/11243/10376/23397/5710/10540/85378/7324/2010/83540/64900/5719/64682/6233/23175/7514/54930/54820/113130/9493/6396/129401/1453/27229/64946/9793/140735/220134/84617/4928/26271/5903/55706/7175/11258/22981/246184/55055/8636/80776/1783/401541/7532/55125/10382/79172/121441/7277/5706/9133/79980/25836/6232/23047/8881/9814/653784/5885/23354/891/5501/9738/1639/5714/55722/4957/4927/5566/54821/81876/9183/5688/1062/699/5687/7283/347733/5708/22919/8243/10426/5529/22994/51143/1069/8086/10393/79648/5577/5704/7311/25906/10383/5347/54892/84790/84643/80184/5694/22897/6418/5108/7112/10592/7280/10806/29781/5595/1778/5516/4000/115106/4926/5905/22995/55559/81929/5684/5720/54908/55143/9631/5525/10142/1058/991/79019/5862/348235/80152/5690/1063/8379/95681/5717/9491/140609/23244/23421/55920/79023/23636/10735/10197/7443/1781/7316/10213/80321/10776/53371/26003/4085/9688/55166/10121/5715/84131/5701/5685/3320/8815/5686/79003/9126/9918/10733/4751/9232/5527/9700/27175/80254/5716/701/57551/9662/55142/64689/8481/5693/5721/55755/8480 308 Human_papillomavirus_type_16 R-HSA-5633007 Regulation of TP53 Activity 152/4644 160/10654 3.963407920652012e-45 2.417678831597727e-43 8.561686675275742e-44 6884/6875/5563/83990/64769/9156/1763/1459/7486/6874/133383/9212/5982/1460/11200/472/53632/79813/639/28996/84289/1457/6790/29117/4194/5928/1432/4683/56950/84126/1107/8900/6873/5371/2475/672/6881/51616/5518/6117/11198/7159/51230/83695/7314/5515/1263/23368/23774/6118/3622/6446/51422/117584/116028/890/983/5519/27154/5458/83860/57459/10000/5985/900/7994/3066/7157/5984/6233/10419/5600/6883/7874/5608/5884/5810/26155/26013/5170/80010/7862/1029/5457/9219/8445/204851/6878/5931/580/11073/80196/54971/641/1108/8148/6119/3364/5571/10524/54457/144715/1616/6794/54815/94241/1111/8626/208/79109/7311/7161/5562/6880/6908/5983/5564/6882/5565/1020/53615/6877/5516/1017/9891/5305/5883/25946/10111/207/22974/6749/545/8550/7316/6872/6879/112858/10848/9099/2033/3065/91875/5527/5932/8851/5300/7156/138474/133746/10919/4193 152 Human_papillomavirus_type_16 R-HSA-69306 DNA Replication 126/4644 127/10654 1.0088378221057393e-44 5.897497768393134e-43 2.088471280850478e-43 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/143471/5705/5709/5422/9978/1869/4174/5695/84515/4998/5711/10926/5683/990/5699/5702/8900/51529/29945/51434/55388/84296/6117/29882/5001/10714/5558/5696/5691/7314/996/5718/6118/23594/5700/122706/5707/64785/23198/898/3978/5557/890/51433/9861/6502/5698/5692/5985/5713/119504/4175/5710/5984/7324/5719/64682/6233/23649/5424/4999/4172/5000/8318/246184/54107/4173/5706/8881/5425/5714/5111/51053/6119/5688/5687/5427/5708/81620/10393/1870/5704/29935/51343/23595/7311/25906/51659/5983/5694/4176/56655/1017/5684/5720/57804/8317/9837/5690/5717/9491/6500/10197/7316/10213/5426/4171/1871/5715/5701/5685/5686/5716/5981/5693/5721 126 Human_papillomavirus_type_16 R-HSA-69239 Synthesis of DNA 118/4644 119/10654 8.177768450083334e-42 4.589363654186767e-40 1.6252238772376143e-40 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/143471/5705/5709/5422/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/84296/6117/29882/5001/10714/5558/5696/5691/7314/996/5718/6118/23594/5700/122706/5707/64785/23198/898/3978/5557/890/51433/9861/6502/5698/5692/5985/5713/119504/4175/5710/5984/7324/5719/64682/6233/23649/5424/4999/4172/5000/8318/246184/54107/4173/5706/8881/5425/5714/5111/6119/5688/5687/5427/5708/81620/10393/5704/51343/23595/7311/25906/51659/5983/5694/4176/56655/1017/5684/5720/57804/9837/5690/5717/9491/6500/10197/7316/10213/5426/4171/5715/5701/5685/5686/5716/5981/5693/5721 118 Human_papillomavirus_type_16 R-HSA-162906 HIV Infection 200/4644 233/10654 1.1511915869233212e-41 6.212006909436229e-40 2.1998478908008404e-40 6884/23165/6875/5689/2237/7852/162/5682/27243/6874/1174/348995/143471/57122/5705/3981/5431/23511/5435/5709/9978/5433/5695/2960/292/567/23279/5711/23327/29082/23225/5683/2965/2534/5699/5439/5702/6873/3836/163/9972/6881/2967/51616/8021/11198/904/55690/51497/5062/55746/5696/5691/7314/5879/5718/8945/51606/161/25978/5700/122706/5707/2959/10053/7518/23198/404672/10015/5438/3978/10762/51534/4836/926/9397/9861/79902/9883/83860/51510/5698/5692/5713/5710/2068/5902/5478/5719/6233/7514/1025/3932/6396/129401/6883/7936/1175/6829/8907/2957/940/25920/1173/4928/2963/5434/5903/55706/7175/5436/6878/4869/5706/160/920/4331/5714/4927/8148/2966/2962/5688/54457/8812/5687/5708/128866/905/2071/5901/8086/5704/7311/6880/6908/7251/8905/5694/1104/2547/6882/2961/5432/22916/1234/6877/5905/3837/6917/81929/5440/164/5684/8065/5720/902/9631/3159/5430/5690/7520/5717/9491/6500/6749/79023/5441/23636/10197/7469/919/4686/7316/10213/6872/53371/3055/9688/6879/9150/5715/9525/5701/5437/5685/8815/5686/6827/2968/5716/9844/375/138474/1022/5693/5721/8178/8480/291 200 Human_papillomavirus_type_16 R-HSA-5683057 MAPK family signaling cascades 239/4644 294/10654 3.0684130140983136e-41 1.5944383180666422e-39 5.6463584508943635e-40 2308/5689/374/2118/3725/2674/4893/6711/2250/1437/71/5682/1844/1850/5526/817/84292/7039/27327/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/5605/4609/5711/3558/3717/5683/145957/2534/3690/408/9965/5699/2264/5702/192669/4296/5894/1847/3563/1741/9542/1739/2885/6709/8660/8997/8826/5518/2252/1740/4140/4343/2253/3845/3265/4763/3569/5062/5696/5691/7314/3572/5879/5515/5923/5718/818/57554/1839/3667/8823/2065/5700/3815/122706/5707/5567/8844/7094/1849/5594/2069/23198/7414/5921/3337/2260/5528/2902/983/3718/2249/6714/9861/2248/5519/3567/2247/5698/5692/5713/2335/1445/5710/8555/896/5719/6233/2246/7514/2251/5154/1843/3570/255324/26523/369/801/7297/5781/8682/11221/805/9462/3562/6464/6712/2904/5747/283455/3674/5568/2322/3315/409/5706/1438/673/2263/4233/5597/84078/5714/5566/5688/5159/5687/5708/3084/5063/5529/816/998/6654/5704/10718/3716/7311/1956/60/5536/5694/5058/7529/5595/25759/5516/8822/5786/27161/815/5684/685/5720/2309/5604/3561/5525/153090/10642/10048/5690/57690/5717/9491/3568/8817/10197/192670/5596/8550/2254/7316/10213/1950/3560/26281/10818/5715/2261/5701/27040/5685/2255/53358/5686/2066/27006/8556/5979/23112/1742/5527/5716/88/5906/5155/4254/5896/808/3559/8202/5693/5721/5245/5156/161742/284 239 Human_papillomavirus_type_16 R-HSA-8856828 Clathrin-mediated endocytosis 137/4644 146/10654 5.4966105332146567e-39 2.7541944921786296e-37 9.753384104050069e-38 5869/374/85439/71/8674/5286/4738/7039/1212/23208/1785/29763/950/8871/10094/554/54874/10980/22848/7037/2017/3482/408/9322/10987/6456/185/8976/30011/2885/163/11037/1759/23149/3312/29993/9185/7314/9856/23396/1839/161/7018/25977/5868/10618/10093/8027/1856/9892/8322/2060/2069/1601/6453/55707/8301/1129/9146/6455/4074/26119/6233/90019/7474/6844/1213/2580/1211/29924/4036/255324/1175/85021/10109/6869/1173/6857/84251/23048/9026/29988/409/112574/382/160/338/8218/920/22905/26052/8867/10092/9829/2873/10097/7311/1956/60/8533/274/51429/8673/3092/50618/51138/9318/685/127833/1080/29978/58513/7316/1950/273/10552/26130/3267/3949/867/9341/915/917/6572/115548/5878/10096/143425/3575/6845/551/154/10254/6457/50813/4952/11252 137 Human_papillomavirus_type_16 R-HSA-168254 Influenza Infection 142/4644 155/10654 3.826830620396712e-37 1.8513942622126163e-35 6.556312351460066e-36 3839/6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/23225/6156/6143/5439/3836/6139/9972/3921/8021/7040/55746/6208/6170/3303/6203/402569/6147/6222/8106/9636/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/7514/1213/5610/1211/6188/6396/129401/6122/6230/4928/2963/3838/5434/5903/6194/55706/7175/6166/5436/6136/6125/821/6232/6160/6193/6210/4927/6229/6205/2962/10898/3840/140801/6235/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/81929/5440/9349/4736/51121/9631/6159/6217/3843/5430/6152/51065/6141/79023/5441/23636/6164/53371/6209/9688/11224/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 142 Human_papillomavirus_type_16 R-HSA-168255 Influenza Life Cycle 133/4644 144/10654 7.753839056722355e-36 3.6262120655271546e-34 1.2841445736045445e-34 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/23225/6156/6143/5439/3836/6139/9972/3921/8021/55746/6208/6170/3303/6203/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/7514/1213/1211/6188/6396/129401/6122/6230/4928/2963/5434/5903/6194/55706/7175/6166/5436/6136/6125/821/6232/6160/6193/6210/4927/6229/6205/2962/140801/6235/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/81929/5440/9349/4736/51121/9631/6159/6217/3843/5430/6152/51065/6141/79023/5441/23636/6164/53371/6209/9688/11224/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 133 Human_papillomavirus_type_16 R-HSA-418594 G alpha (i) signalling events 298/4644 406/10654 2.2232503157202997e-35 1.0062000622437356e-33 3.5632398948046917e-34 729230/2788/10316/6000/2780/1880/7852/50833/29899/5331/5726/338442/64805/2770/817/1237/2550/5578/50832/3354/2841/5582/4987/51289/259294/2912/3576/6360/5530/4985/2920/2921/1236/259295/107/6010/9568/2840/2831/5948/5367/4988/6370/58191/6755/1524/643/2782/5949/5499/339403/4023/2914/8843/2847/2833/9290/5518/9170/6382/187/6750/6004/259296/259289/50835/2587/53829/814/2773/5515/2787/6387/818/4544/4543/126006/10663/4889/9283/727/338398/117579/3579/23566/2358/5567/2916/259293/5594/5179/10681/112/8811/5573/348/56923/2832/5528/27199/2826/8786/6376/165140/27198/111/5443/4836/3627/2792/9397/54429/6714/336/3361/6346/5519/134/5588/6295/1129/51083/2785/2783/2784/1233/6366/5613/2861/2771/728/183/10022/5580/6373/57121/1132/1814/80835/4036/6357/196883/9672/115/8698/5999/801/9934/50840/2791/4647/50865/805/10803/2913/3838/7276/351/11251/3352/8484/6351/6752/1903/84539/6753/5568/3577/2918/5368/6754/131890/8862/301/56670/150/113/338/2868/335/2853/6751/186/53637/10645/5566/84254/10563/5540/1901/5733/256933/10850/624/4852/816/2786/50838/5577/5473/4283/11255/10874/83756/611/56477/1020/259286/3350/129521/1234/109/9628/5516/151/57007/815/26086/5321/9294/54331/283869/2817/6017/5575/59345/63940/4986/6374/5539/259287/2852/50836/3339/1230/5532/846/4886/2919/51764/94235/114/259290/6383/108/5196/3827/5173/2357/55970/2778/6352/140/10768/346562/152/5957/6364/80834/259292/3949/2793/5030/5697/5576/3355/5534/3351/4035/6288/6372/50834/259285/79823/1385/7804/5144/719/6363/2917/1268/50831/2359/50839/808/5660/1815/1325/1232/1902/50837/5137/1269/59340/4887/2790/718/623 298 Human_papillomavirus_type_16 R-HSA-9607240 FLT3 Signaling 214/4644 267/10654 3.172302296918059e-35 1.3908562883050116e-33 4.9254167241622504e-34 5295/5689/374/2674/4893/6711/2250/1437/71/5682/1844/5291/1850/5526/817/84292/7039/5908/3082/143471/2064/5705/8452/6776/4684/5709/9978/5695/1852/2668/5605/5711/3558/3717/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/1847/3563/1741/9542/1739/2885/6709/8660/8826/9846/5518/2252/1740/4140/2253/3845/3265/4763/5696/5691/7314/5515/54106/5923/5718/818/57554/1839/5290/3667/8823/2065/5700/3815/122706/5707/8844/7094/1849/5594/2069/23198/7414/57761/5921/2260/5528/2902/3718/2249/6714/9861/2248/5519/3567/2247/5698/5692/5713/2335/1445/5710/5719/6233/2246/2251/5154/1843/6777/255324/369/801/5781/8682/11221/805/5170/9462/3562/6464/6712/2904/5747/283455/3674/2322/409/5706/1438/673/2263/4233/84078/5714/5688/5159/5687/5708/3084/5529/816/208/6654/5704/10718/3716/7311/1956/60/5536/2549/5694/7529/5595/25759/5516/8822/5786/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10197/2254/7316/10213/1950/3560/5289/3055/26281/10818/5715/2261/5701/27040/5685/2255/53358/5686/2066/27006/5979/1742/5527/5716/88/5906/5155/4254/5296/808/3559/5693/5721/5245/5156/161742/284 214 Human_papillomavirus_type_16 R-HSA-5684996 MAPK1/MAPK3 signaling 205/4644 255/10654 3.907637650511647e-34 1.6613380677781336e-32 5.883269445108445e-33 5689/374/2674/4893/6711/2250/1437/71/5682/1844/1850/5526/817/84292/7039/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/5605/5711/3558/3717/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/1847/3563/1741/9542/1739/2885/6709/8660/8826/5518/2252/1740/4140/2253/3845/3265/4763/3569/5696/5691/7314/3572/5515/5923/5718/818/57554/1839/3667/8823/2065/5700/3815/122706/5707/8844/7094/1849/5594/2069/23198/7414/5921/2260/5528/2902/983/3718/2249/6714/9861/2248/5519/3567/2247/5698/5692/5713/2335/1445/5710/5719/6233/2246/2251/5154/1843/3570/255324/369/801/7297/5781/8682/11221/805/9462/3562/6464/6712/2904/5747/283455/3674/2322/409/5706/1438/673/2263/4233/84078/5714/5688/5159/5687/5708/3084/5529/816/6654/5704/10718/3716/7311/1956/60/5536/5694/7529/5595/25759/5516/8822/5786/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10197/2254/7316/10213/1950/3560/26281/10818/5715/2261/5701/27040/5685/2255/53358/5686/2066/27006/5979/1742/5527/5716/88/5906/5155/4254/808/3559/5693/5721/5245/5156/161742/284 205 Human_papillomavirus_type_16 R-HSA-376176 Signaling by ROBO receptors 180/4644 218/10654 5.7751672166541804e-33 2.383105766166416e-31 8.439253641674221e-32 6158/5689/6138/6227/7852/6206/6234/6191/6128/5682/6132/10298/6129/6176/5578/6224/6146/6154/26986/143471/6202/5705/6169/8829/23122/5709/6175/9978/6218/5695/65109/6173/6167/5711/1605/5683/6156/5699/6143/9495/5702/6139/10487/8440/3921/23332/5062/6208/5696/6170/5691/7314/5879/6387/5718/25/6203/8861/6147/5700/122706/5707/5567/6222/23198/27/26019/2935/6134/6091/22794/6155/4116/6714/6231/9861/6142/23521/10486/5698/5692/5713/1981/5710/6207/5719/6233/6188/6122/6230/1287/6194/2107/6166/56924/6136/5568/6125/5706/6232/6160/55110/5714/6193/6210/6229/6205/5566/5688/5687/5708/5063/140801/6235/6181/998/9939/6654/5704/7311/6223/25873/387/6655/5694/5058/9045/6187/6168/22916/6157/6137/10921/6144/55740/5684/9349/4736/5720/51121/2817/6159/4690/6217/6152/5690/5532/5717/9491/51065/6141/10197/6164/4686/7316/10213/5216/6209/11224/6130/5715/6204/5701/6228/5576/5685/5686/7408/6124/8453/5716/23380/6189/9775/6135/6201/6161/5693/5721/6133 180 Human_papillomavirus_type_16 R-HSA-168273 Influenza Viral RNA Transcription and Replication 123/4644 134/10654 1.604225667377097e-32 6.4306531752287636e-031 2.2772767368480895e-31 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/23225/6156/6143/5439/6139/9972/3921/8021/55746/6208/6170/6203/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/6188/6396/129401/6122/6230/4928/2963/5434/5903/6194/55706/7175/6166/5436/6136/6125/6232/6160/6193/6210/4927/6229/6205/2962/140801/6235/6181/8086/7311/6223/25873/9045/6187/5432/6168/6157/6137/6144/81929/5440/9349/4736/51121/9631/6159/6217/3843/5430/6152/51065/6141/79023/5441/23636/6164/53371/6209/9688/11224/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 123 Human_papillomavirus_type_16 R-HSA-5673001 RAF/MAP kinase cascade 199/4644 249/10654 1.7254386044719413e-32 6.724417672428149e-31 2.381307079856013e-31 5689/374/2674/4893/6711/2250/1437/71/5682/1844/1850/5526/817/84292/7039/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/5605/5711/3558/3717/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/1847/3563/1741/9542/1739/2885/6709/8660/8826/5518/2252/1740/4140/2253/3845/3265/4763/5696/5691/7314/5515/5923/5718/818/57554/1839/3667/8823/2065/5700/3815/122706/5707/8844/7094/1849/5594/2069/23198/7414/5921/2260/5528/2902/3718/2249/6714/9861/2248/5519/3567/2247/5698/5692/5713/2335/1445/5710/5719/6233/2246/2251/5154/1843/255324/369/801/8682/11221/805/9462/3562/6464/6712/2904/5747/283455/3674/2322/409/5706/1438/673/2263/4233/84078/5714/5688/5159/5687/5708/3084/5529/816/6654/5704/10718/3716/7311/1956/60/5536/5694/7529/5595/25759/5516/8822/5786/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10197/2254/7316/10213/1950/3560/26281/10818/5715/2261/5701/27040/5685/2255/53358/5686/2066/27006/5979/1742/5527/5716/88/5906/5155/4254/808/3559/5693/5721/5245/5156/161742/284 199 Human_papillomavirus_type_16 R-HSA-72613 Eukaryotic Translation Initiation 112/4644 119/10654 2.1814307335991566e-32 8.054071892735832e-31 2.8521753635977892e-31 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/1978/6122/1968/6230/8669/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/8893/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/8891/51121/6159/6217/6152/51065/6141/10480/1967/6164/8661/9669/6209/1964/11224/6130/8890/6204/6228/6124/3646/6189/6135/6201/6161/8892/6133 112 Human_papillomavirus_type_16 R-HSA-72737 Cap-dependent Translation Initiation 112/4644 119/10654 2.1814307335991566e-32 8.054071892735832e-31 2.8521753635977892e-31 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/1978/6122/1968/6230/8669/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/8893/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/8891/51121/6159/6217/6152/51065/6141/10480/1967/6164/8661/9669/6209/1964/11224/6130/8890/6204/6228/6124/3646/6189/6135/6201/6161/8892/6133 112 Human_papillomavirus_type_16 R-HSA-5357801 Programmed Cell Death 155/4644 181/10654 3.070384768130346e-32 1.10455123838125e-30 3.9115293132456777e-31 5689/5682/4976/7531/55075/356/10971/10059/7533/2810/143471/5705/5709/1869/5695/8655/660/5711/836/5683/929/324/5699/9414/5702/4001/3836/6709/6093/840/7159/26060/637/5062/5696/5691/7314/578/23368/5718/2934/11035/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/100506658/7082/5339/4836/8797/9861/28988/10134/22900/999/5588/598/5698/10000/5692/708/5713/5710/3002/7157/5719/6233/5580/1613/839/7029/8772/331/8717/57099/317/8743/140735/1828/5747/1029/7532/330/118/5706/1829/6774/5366/5714/8428/5688/5687/1832/56616/5708/8837/8626/197259/208/5704/7311/7161/5694/8795/3148/7529/5595/23643/4000/27113/3837/596/5684/5720/7186/51765/1499/10018/842/207/5690/5717/9491/355/10197/7099/7316/10213/54205/3146/5715/23604/5701/329/5685/5686/5534/4137/5716/581/5599/353376/7431/5693/5721/6304/148022 155 Human_papillomavirus_type_16 R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 91/4644 92/10654 4.874256911882894e-32 1.679636740482199e-30 5.948070236767813e-31 6884/6875/5563/83990/9156/1763/1459/7486/6874/9212/5982/1460/11200/472/53632/28996/1457/6790/4194/1432/4683/84126/8900/6873/672/6881/51616/6117/11198/83695/7314/1263/6118/51422/116028/890/83860/5985/7157/5984/6233/5600/6883/5884/5810/26155/80010/8445/204851/6878/580/11073/641/8148/6119/3364/5571/10524/54457/144715/6794/94241/1111/7311/5562/6880/6908/5983/5564/6882/5565/1020/6877/1017/9891/5883/10111/22974/6749/545/8550/7316/6872/6879/112858/5932/8851/5300/7156/138474/4193 91 Human_papillomavirus_type_16 R-HSA-162909 Host Interactions of HIV factors 119/4644 129/10654 4.908418129705642e-32 1.679636740482199e-30 5.948070236767813e-31 23165/5689/162/5682/1174/348995/143471/57122/5705/23511/5709/9978/5695/292/567/23279/5711/23225/5683/2534/5699/5702/3836/163/9972/8021/904/55690/5062/55746/5696/5691/7314/5879/5718/8945/51606/161/5700/122706/5707/10053/23198/10762/926/9861/79902/9883/5698/5692/5713/5710/5902/5478/5719/6233/7514/1025/3932/6396/129401/1175/8907/940/1173/4928/5903/55706/7175/4869/5706/160/920/5714/4927/5688/5687/5708/5901/8086/5704/7311/8905/5694/1104/5905/3837/81929/164/5684/8065/5720/9631/3159/5690/5717/9491/6500/79023/23636/10197/919/7316/10213/53371/3055/9688/5715/5701/5685/8815/5686/5716/9844/375/5693/5721/8480/291 119 Human_papillomavirus_type_16 R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 122/4644 134/10654 2.1970355700994403e-31 7.339145011546464e-30 2.5989994713958295e-30 5295/8454/5689/3725/4893/5335/4790/5682/5291/7321/143471/5705/5530/5709/5695/4792/5711/5683/2534/5699/5702/2885/9846/3845/7334/3265/3551/5062/5696/5691/7314/5879/257397/5718/8945/5601/4773/5290/5700/122706/5707/5336/5594/4214/23198/23118/10892/8517/5970/9861/5588/5698/5692/5713/5710/10454/5719/6233/7410/7409/3702/2353/801/805/5170/6464/2205/4772/3937/4775/10451/5706/2206/6850/8915/5714/5688/5687/4067/5708/5602/695/7189/6654/5704/7311/5694/5058/6416/997/5595/1147/9402/5684/5720/6885/84433/5690/5532/5717/9491/6500/10197/7316/10213/10768/7322/5715/5701/27040/23291/5685/5686/5534/5609/5716/5296/808/5599/5693/5721/2207 122 Human_papillomavirus_type_16 R-HSA-109581 Apoptosis 152/4644 178/10654 2.4468472686276384e-31 7.983550506708318e-30 2.8272017400054965e-30 5689/5682/4976/7531/55075/356/10971/10059/7533/2810/143471/5705/5709/1869/5695/8655/660/5711/836/5683/929/324/5699/9414/5702/4001/3836/6709/6093/840/7159/26060/637/5062/5696/5691/7314/578/23368/5718/2934/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/100506658/7082/5339/4836/8797/9861/28988/10134/22900/999/5588/598/5698/10000/5692/708/5713/5710/3002/7157/5719/6233/5580/1613/839/7029/8772/331/8717/57099/317/8743/140735/1828/5747/1029/7532/118/5706/1829/6774/5366/5714/8428/5688/5687/1832/56616/5708/8837/8626/208/5704/7311/7161/5694/8795/3148/7529/5595/23643/4000/27113/3837/596/5684/5720/7186/51765/1499/10018/842/207/5690/5717/9491/355/10197/7099/7316/10213/54205/3146/5715/23604/5701/329/5685/5686/5534/4137/5716/581/5599/353376/7431/5693/5721/6304/148022 152 Human_papillomavirus_type_16 R-HSA-69618 Mitotic Spindle Checkpoint 106/4644 112/10654 2.5625586018812158e-31 7.998764808669905e-30 2.832589555983191e-30 55839/11130/11065/6249/9735/7321/5526/8697/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/996/5515/79682/10403/25936/3619/64105/332/5528/51433/79902/3796/5519/81565/91687/119504/11243/7324/83540/64682/7514/54820/6396/64946/9793/140735/220134/4928/5903/246184/55055/80776/1783/401541/79172/79980/6232/8881/5501/54821/9183/1062/699/22919/5529/51143/10393/25906/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/55166/79003/5527/701/57551 106 Human_papillomavirus_type_16 R-HSA-69052 Switching of origins to a post-replicative state 89/4644 90/10654 2.5655339728449446e-31 7.998764808669905e-30 2.832589555983191e-30 8454/5689/9134/11065/5682/7321/8697/143471/5705/5709/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/29882/5001/5696/5691/7314/996/5718/23594/5700/122706/5707/23198/898/890/51433/9861/6502/5698/5692/5713/119504/4175/5710/7324/5719/64682/6233/4999/4172/5000/246184/4173/5706/8881/5714/5688/5687/5708/81620/10393/5704/51343/23595/7311/25906/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 89 Human_papillomavirus_type_16 R-HSA-2262752 Cellular responses to stress 331/4644 479/10654 8.60638439900919e-31 2.6249472416978026e-29 9.295682920668965e-30 1912/23165/5689/3725/6782/9134/11065/573/4790/5682/64344/7531/1915/7321/51807/817/6045/8697/9530/23677/27327/80012/7295/5925/3091/348995/143471/472/10381/57122/5705/79813/3576/3313/1780/7001/23511/10312/5709/9978/2114/1869/5695/3305/8655/84516/1911/832/26277/23279/4194/1031/5711/5928/1432/1387/4683/7846/259217/23225/5683/3309/23512/57332/5699/7428/5702/192669/9531/81027/8900/51529/4001/29945/8091/8131/2056/51434/2475/1032/3306/1030/6196/9972/23411/8021/4343/6117/6197/29882/3312/4217/54386/3569/55746/5696/5691/7296/7314/51164/996/51182/5718/818/3303/7014/6118/51606/5601/79861/5606/7027/5700/122706/5707/2146/9114/5594/3308/23198/898/10049/10013/27244/3337/10762/847/7323/890/5970/9261/6667/51433/9861/79902/5598/9883/2932/84733/9973/5698/5692/5713/2877/119504/10376/6195/5710/3301/10540/7157/7324/5719/64682/6233/2353/7029/8726/6396/1535/129401/5600/523/201163/26523/405/5608/3297/57521/140735/768/6015/84617/4928/1019/5903/83667/55706/7175/5241/11258/9448/246184/112399/1029/1783/8535/84962/10382/93661/5931/10294/55860/830/7013/7277/1051/1410/50488/5706/10671/8881/6774/1639/5714/4927/7867/6119/3552/10370/10524/5688/5687/57805/3310/2908/347733/5708/5602/7266/6009/51143/816/6648/8086/10393/1870/5704/3326/51343/7311/367/25906/2034/79400/57634/10383/84790/55662/648/5694/3304/23466/3456/2113/6416/10641/7280/10728/829/23523/5595/1778/1017/815/25913/81929/5684/5720/9631/3159/7290/10111/7422/5690/57690/5717/1027/9491/545/79023/23636/10197/192670/10808/3490/8550/29855/4306/1781/7316/10213/10935/53371/1026/9532/54205/2289/9588/9688/10121/7415/1871/6647/7322/5715/5701/112398/5685/3320/65057/5686/2033/1021/6767/25842/8453/23135/10963/22824/57600/23112/5609/10542/5716/9529/5599/54583/5052/96459/5693/5721/55466/2288/5034/8480/10919/2950/4193/9296/23043 331 Human_papillomavirus_type_16 R-HSA-5620912 Anchoring of the basal body to the plasma membrane 95/4644 98/10654 9.14705042948359e-31 2.7304918622479736e-29 9.669446366665744e-30 79867/7531/11190/203068/54801/85302/79441/5116/5048/22832/8655/9702/132320/7846/7840/11064/84902/5518/55835/23332/93323/1454/54806/91147/983/79959/10540/117177/57545/26005/54930/54820/23322/1453/9793/4218/11258/22981/8636/54903/80776/7532/55125/10382/121441/7277/9814/23354/146057/9738/1639/55722/4957/5566/7283/22919/27077/22994/4867/1069/5577/10383/5347/80184/22897/5108/261734/57787/10806/9657/1778/115106/22995/55559/10142/51134/95681/1781/80321/8766/79598/10121/347240/84131/3320/79600/10733/4751/80254/26123/9662/55142/8481/51259/55755 95 Human_papillomavirus_type_16 R-HSA-500792 GPCR ligand binding 324/4644 468/10654 2.1934412131730524e-30 6.411245879337067e-29 2.270404062758072e-29 729230/2788/2532/4160/10316/2149/1880/3972/1816/7852/2692/10161/50833/83551/3363/5726/338442/155/2740/64805/1237/5734/2550/50832/3354/2841/2696/4987/51289/3360/117/259294/3060/2912/6349/3576/6360/4985/2920/2921/1236/259295/799/6010/9568/554/2911/2840/2831/5367/5741/4988/6370/58191/153/6755/1524/1081/643/2782/4161/185/339403/2914/8843/2847/10267/2833/6347/9290/9170/6469/187/6750/259296/259289/50835/2587/53829/2787/6387/4544/4543/10663/4889/9283/727/122042/7476/1909/5732/338398/117579/133/3579/2492/23566/2358/2916/319100/259293/8322/5179/10681/27202/6367/7471/8811/1812/56923/2832/27199/2826/5727/6376/165140/27198/5443/6354/3627/2792/54429/3361/6346/151306/134864/134/9034/59350/5744/2863/1129/51554/51083/2785/2783/2784/2829/1233/6366/1241/2861/728/7474/183/10022/170589/6373/57121/5731/1132/1814/80835/3362/6357/4159/8698/9934/2151/6869/6361/50840/2791/10268/6343/1813/50865/10803/2913/9340/116/351/11251/3352/8484/6344/6351/4158/6863/6752/1903/84539/6753/3577/594857/4157/2918/5368/6754/6915/8862/301/5032/2642/56670/150/2853/6751/5020/186/53637/10563/5540/1901/5733/256933/7252/5729/10850/79924/624/2641/1392/4852/9287/134860/2786/50838/5473/4283/1910/11255/122876/113091/10874/83756/6356/611/56477/387129/259286/3350/129521/1234/151/57007/7432/9294/54331/1128/283869/59345/4986/6608/6374/2488/5539/259287/136/2852/50836/1230/846/4886/2919/7433/10266/5745/51764/94235/2695/259290/5196/3827/5746/1604/5173/2357/796/55970/2778/6352/140/6348/9038/152/2691/1906/6364/7253/80834/259292/2793/5030/5697/3640/3355/3351/6288/6372/797/5739/50834/259285/3973/7434/10203/719/6363/2917/1268/50831/3375/2359/1395/50839/2846/5660/1815/1325/1232/1902/551/154/50837/1269/3274/59340/5724/4887/1394/2790/718/623 324 Human_papillomavirus_type_16 R-HSA-9010553 Regulation of expression of SLITs and ROBOs 146/4644 171/10654 3.972763545871418e-30 1.1375076030321631e-28 4.028237150700987e-29 6158/5689/6138/6227/6206/6234/6191/6128/5682/6132/6129/6176/6224/6146/6154/26986/143471/6202/5705/6169/5709/6175/9978/6218/5695/65109/6173/6167/5711/1605/5683/6156/5699/6143/5702/6139/3921/6208/5696/6170/5691/7314/5718/6203/8861/6147/5700/122706/5707/6222/23198/26019/2935/6134/6091/22794/6155/4116/6231/9861/6142/23521/5698/5692/5713/1981/5710/6207/5719/6233/6188/6122/6230/1287/6194/2107/6166/6136/6125/5706/6232/6160/55110/5714/6193/6210/6229/6205/5688/5687/5708/140801/6235/6181/9939/5704/7311/6223/25873/5694/9045/6187/6168/22916/6157/6137/10921/6144/5684/9349/4736/5720/51121/6159/6217/6152/5690/5717/9491/51065/6141/10197/6164/4686/7316/10213/6209/11224/6130/5715/6204/5701/6228/5685/5686/6124/8453/5716/6189/9775/6135/6201/6161/5693/5721/6133 146 Human_papillomavirus_type_16 R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 105/4644 112/10654 5.173290932385834e-30 1.4516254356274648e-28 5.140617515970765e-29 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/6202/6169/6175/6218/6173/6167/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/6122/1968/6230/8669/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6164/8661/9669/6209/1964/11224/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 105 Human_papillomavirus_type_16 R-HSA-202403 TCR signaling 110/4644 119/10654 6.704055922467682e-30 1.8396283731960954e-28 6.514646000289283e-29 5295/8454/5689/5335/4790/5682/5291/7321/143471/5705/5788/3115/5709/5695/4792/3113/5711/3117/5683/55824/5699/5702/26191/3127/7334/3551/5062/5696/5691/7314/5718/8945/5290/5700/122706/5707/8767/23198/23118/10892/8517/3126/5970/9861/5588/5698/5692/5713/1445/5710/916/5719/6233/3702/3932/3120/5170/3937/3123/5706/3122/920/8915/5714/5795/5688/5687/5708/5063/7189/7535/5704/7311/3125/5694/5058/997/1147/55740/9402/5684/5720/6885/4690/3119/84433/5690/5717/9491/6500/10197/919/7316/10213/7322/5715/5701/27040/23291/915/5685/917/5686/7408/5728/7454/5716/5296/5693/5721 110 Human_papillomavirus_type_16 R-HSA-2500257 Resolution of Sister Chromatid Cohesion 115/4644 126/10654 6.818294754540055e-30 1.8396283731960954e-28 6.514646000289283e-29 55839/11130/6249/9735/5526/51807/9212/10274/147841/348995/10381/57122/1780/23122/5048/57405/8655/23279/2491/7846/1060/81027/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/79861/25936/55869/3619/64105/332/5528/983/79902/3796/5519/81565/91687/11243/10376/83540/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/55055/80776/1783/401541/10382/79172/7277/9133/79980/6232/23047/5885/891/5501/54821/9183/1062/699/347733/22919/8243/5529/51143/10383/5347/84790/84643/7280/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23244/23421/55920/79023/10735/1781/4085/55166/79003/9126/5527/701/57551 115 Human_papillomavirus_type_16 R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 85/4644 86/10654 7.086367284540827e-30 1.8411432037427372e-28 6.520010445035615e-29 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 85 Human_papillomavirus_type_16 R-HSA-453276 Regulation of mitotic cell cycle 85/4644 86/10654 7.086367284540827e-30 1.8411432037427372e-28 6.520010445035615e-29 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 85 Human_papillomavirus_type_16 R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 104/4644 111/10654 1.1268478474732023e-29 2.874486418190732e-28 1.0179371942724431e-28 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/51386/6188/6122/1968/6230/8669/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6164/8661/6209/1964/11224/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 104 Human_papillomavirus_type_16 R-HSA-69002 DNA Replication Pre-Initiation 84/4644 85/10654 1.6235239560808382e-29 3.9961475620726597e-28 1.4151492285690777e-28 5689/5682/143471/5705/5709/5422/1869/4174/5695/84515/4998/5711/10926/5683/990/5699/5702/55388/6117/5001/5558/5696/5691/7314/5718/6118/23594/5700/122706/5707/23198/5557/9861/5698/5692/5713/4175/5710/5719/6233/23649/4999/4172/5000/8318/54107/4173/5706/5714/51053/6119/5688/5687/5427/5708/81620/1870/5704/29935/23595/7311/5694/4176/56655/1017/5684/5720/8317/5690/5717/9491/10197/7316/10213/5426/4171/1871/5715/5701/5685/5686/5716/5693/5721 84 Human_papillomavirus_type_16 R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 84/4644 85/10654 1.6235239560808382e-29 3.9961475620726597e-28 1.4151492285690777e-28 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/91768/5934/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/7029/1163/1019/5706/286826/4331/5714/5688/5687/91750/5708/1874/208/5704/55957/51343/7311/5694/1017/5684/994/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5715/5701/5685/5686/5716/1022/5693/5721/132660 84 Human_papillomavirus_type_16 R-HSA-8953897 Cellular responses to external stimuli 335/4644 493/10654 5.332752061379255e-29 1.28997433484743e-27 4.568165105210541e-28 1912/23165/5689/3725/6782/9134/11065/573/4790/5682/64344/7531/1915/7321/51807/817/6045/8697/9530/23677/27327/80012/7295/5925/3091/348995/143471/472/10381/57122/5705/79813/3576/3313/1780/7001/23511/10312/5709/9978/2114/1869/5695/3305/8655/84516/1911/832/26277/23279/4194/1031/4493/5711/5928/1432/1387/4683/7846/259217/23225/5683/3309/23512/57332/5699/7428/5702/192669/9531/81027/8900/51529/4001/29945/8091/8131/2056/51434/2475/1032/3306/1030/6196/9972/23411/8021/4343/6117/6197/29882/3312/4217/54386/3569/55746/5696/5691/7296/7314/51164/996/51182/5718/818/3303/7014/6118/51606/5601/79861/5606/7027/5700/122706/5707/2146/9114/5594/3308/23198/898/10049/10013/27244/3337/10762/847/7323/1465/890/5970/9261/6667/51433/9861/79902/5598/9883/2932/84733/9973/5698/5692/5713/2877/119504/10376/6195/5710/3301/10540/7157/7324/5719/64682/6233/2353/7029/8726/6396/1535/129401/5600/523/201163/26523/405/5608/3297/57521/140735/768/6015/84617/4928/1019/5903/83667/55706/7175/5241/11258/9448/246184/112399/1029/1783/8535/84962/10382/93661/5931/10294/55860/830/7013/7277/1051/1410/50488/5706/10671/8881/6774/1639/5714/4927/7867/6119/3552/10370/10524/5688/5687/57805/3310/2908/347733/5708/5602/7266/6009/51143/816/6648/8086/10393/1870/5704/3326/51343/7311/367/25906/2034/79400/57634/10383/84790/55662/648/5694/3304/23466/3456/2113/6416/10641/7280/10728/829/23523/5595/1778/1017/815/25913/81929/5684/5720/9631/3159/7290/10111/4502/7422/5690/57690/5717/1027/9491/545/79023/23636/10197/192670/10808/3490/8550/29855/4306/1781/7316/10213/10935/53371/1026/9532/54205/2289/9588/9688/10121/7415/1871/6647/7322/5715/5701/112398/5685/3320/65057/5686/2033/1021/6767/25842/8453/23135/10963/22824/57600/23112/5609/10542/5716/9529/4520/5599/54583/5052/96459/5693/5721/55466/2288/5034/8480/10919/2950/4193/9296/23043 335 Human_papillomavirus_type_16 R-HSA-69202 Cyclin E associated events during G1/S transition 82/4644 83/10654 8.515063227879205e-29 2.0248531709685633e-27 7.170579560319331e-28 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/91768/5934/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/7029/1163/1019/5706/286826/4331/5714/5688/5687/91750/5708/1874/208/5704/55957/7311/5694/1017/5684/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5715/5701/5685/5686/5716/1022/5693/5721/132660 82 Human_papillomavirus_type_16 R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 101/4644 108/10654 1.1595104341074826e-28 2.709423281281645e-27 9.594836543984218e-28 5295/3605/7124/2308/1052/7291/356/3593/246/9021/6624/3082/5743/3091/10538/3383/6097/6657/3576/3662/3688/4985/7133/3606/4609/4988/3717/6347/7040/3312/3569/4692/3596/3598/3592/7412/4582/6367/4312/6778/332/4313/3565/3976/5443/3718/149233/598/2247/2335/595/7157/2353/604/7076/51561/3570/7297/9655/3566/7184/3684/4318/3726/58480/301/6774/6772/8651/1901/3552/79923/112744/3716/240/6356/5008/3586/596/2208/2309/3561/207/5292/5451/7422/3553/2625/3597/4314/1026/3320/4843/6288/6935/3687/7431/3162/1278/4170/3689 101 Human_papillomavirus_type_16 R-HSA-877300 Interferon gamma signaling 89/4644 92/10654 1.1780101222963673e-28 2.709423281281645e-27 9.594836543984218e-28 80263/5777/960/5770/3107/817/9021/3383/55223/3662/3115/4684/567/6672/3113/3106/3459/3717/3117/11074/5371/3133/117854/3127/4938/4261/818/115362/7412/85363/9830/163351/3126/2634/115361/10475/10437/10612/3458/3661/5580/81603/10107/4940/5781/3660/8554/3135/3665/3120/10379/2633/3123/23650/2209/8638/7706/23087/3122/3394/3663/6772/8651/3659/2635/5771/816/10346/3716/3125/7726/79097/3105/3460/815/6737/23321/4281/3119/4502/51127/3664/4939/388646/7341/55128/3134/80128/5724 89 Human_papillomavirus_type_16 R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 79/4644 80/10654 1.020722833343217e-27 2.3097969922266668e-26 8.179646474329346e-27 8454/5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 79 Human_papillomavirus_type_16 R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 85/4644 88/10654 2.975715654105346e-27 6.626871528110795e-26 2.346763222619421e-26 8454/7531/11190/203068/54801/79441/5116/5048/8655/6790/9702/7846/7840/11064/5518/55835/23332/93323/7314/8945/4659/1454/983/79959/10540/6233/54930/54820/1453/9793/4218/5500/11258/22981/8636/7532/84962/55125/10382/121441/7277/9133/9814/23354/891/9738/1639/55722/4957/5566/7283/22919/22994/79866/1069/5577/7311/10133/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/6500/1781/7316/80321/10121/84131/23291/3320/10733/4751/80254/9662/55142/8481/55755 85 Human_papillomavirus_type_16 R-HSA-5663220 RHO GTPases Activate Formins 122/4644 140/10654 3.966392996496704e-27 8.561306729361347e-26 3.0318016102776426e-26 55839/11130/71/6249/9735/5526/51807/9212/388/147841/348995/10381/57122/1780/23122/3688/5048/57405/8655/23279/2491/7846/1060/81027/11004/1855/9184/5518/23332/25909/10726/81930/55746/5879/5515/79682/10403/79861/25936/1856/389/3619/64105/332/5528/6714/79902/3796/5519/81565/91687/11243/10376/23002/83540/1857/7514/54820/29984/1729/6396/64946/9793/140735/220134/84617/4928/114793/5903/55055/80776/1783/401541/10382/79172/7277/79980/6232/5501/54821/9183/1062/699/347733/22919/5529/51143/998/10383/5347/387/60/84790/84643/7280/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/5216/81624/55166/79003/5527/701/23380/57551 122 Human_papillomavirus_type_16 R-HSA-6807070 PTEN Regulation 122/4644 140/10654 3.966392996496704e-27 8.561306729361347e-26 3.0318016102776426e-26 1912/5689/3725/6591/5682/1822/1459/9112/6045/27327/80012/1460/143471/5705/5709/5695/1457/1911/4734/11060/5711/5928/5683/23512/57332/5699/2444/5702/192669/1107/5371/2475/1386/4343/5696/5691/7314/5718/23186/5700/122706/5707/2146/51564/5594/84232/23198/9861/7101/84733/57459/5698/10000/5692/5713/5710/3066/7157/5719/6233/331/8726/26523/7874/57521/23608/6015/9219/8535/5931/5706/8658/5714/1108/2122/10014/5688/5687/5708/54815/6009/208/5704/57504/7311/648/5694/23466/53615/5595/27161/5684/8841/5720/5468/5978/10273/207/5690/57690/5717/9491/10197/192670/7316/10213/57167/5715/1958/5701/5685/5686/5728/6615/3065/23028/5987/23112/10542/5716/5693/5721 122 Human_papillomavirus_type_16 R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 98/4644 106/10654 9.007757652300883e-27 1.9148309069966876e-25 6.780959508590139e-26 374/85439/8674/4738/7039/1212/23208/950/554/10980/22848/7037/3482/408/10987/6456/185/30011/2885/163/11037/23149/9185/7314/9856/1839/161/7018/25977/10618/8027/1856/9892/8322/2060/2069/1601/6453/55707/8301/1129/9146/6455/4074/26119/6233/90019/7474/6844/1213/1211/29924/4036/255324/1175/85021/6869/1173/6857/84251/29988/409/160/338/8218/920/22905/2873/7311/1956/8533/8673/50618/51138/9318/685/127833/1080/29978/58513/7316/1950/3267/3949/867/9341/915/917/6572/115548/143425/3575/6845/551/154/10254/6457/50813 98 Human_papillomavirus_type_16 R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 80/4644 82/10654 1.049376686516651e-26 2.1651110164453845e-25 7.667272384456026e-26 114791/10844/440145/7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/1454/983/79959/80097/10540/85378/54930/54820/1453/27229/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/728642/9738/1639/55722/4957/5566/7283/22919/984/10426/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 80 Human_papillomavirus_type_16 R-HSA-380287 Centrosome maturation 80/4644 82/10654 1.049376686516651e-26 2.1651110164453845e-25 7.667272384456026e-26 114791/10844/440145/7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/1454/983/79959/80097/10540/85378/54930/54820/1453/27229/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/728642/9738/1639/55722/4957/5566/7283/22919/984/10426/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 80 Human_papillomavirus_type_16 R-HSA-202424 Downstream TCR signaling 92/4644 98/10654 1.4932550855916493e-26 3.03628534070302e-25 1.0752347832177856e-25 5295/8454/5689/4790/5682/5291/7321/143471/5705/3115/5709/5695/4792/3113/5711/3117/5683/5699/5702/3127/7334/3551/5696/5691/7314/5718/8945/5290/5700/122706/5707/8767/23198/23118/10892/8517/3126/5970/9861/5588/5698/5692/5713/5710/916/5719/6233/3932/3120/5170/3123/5706/3122/920/8915/5714/5688/5687/5708/7189/5704/7311/3125/5694/997/1147/5684/5720/6885/3119/84433/5690/5717/9491/6500/10197/919/7316/10213/7322/5715/5701/23291/915/5685/917/5686/5728/5716/5296/5693/5721 92 Human_papillomavirus_type_16 R-HSA-72689 Formation of a pool of free 40S subunits 94/4644 101/10654 2.59959880406524e-26 5.210338745862188e-25 1.8451287752162306e-25 6158/6138/6227/6206/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/8663/23521/6207/6233/51386/6188/6122/6230/8669/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/8664/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6164/8661/6209/1964/11224/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 94 Human_papillomavirus_type_16 R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 75/4644 76/10654 2.7893553406525587e-26 5.5119232999092115e-25 1.9519284222209158e-25 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 75 Human_papillomavirus_type_16 R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 74/4644 75/10654 6.372916547756884e-26 1.2418335995142927e-24 4.397685103130481e-25 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 74 Human_papillomavirus_type_16 R-HSA-141424 Amplification of signal from the kinetochores 90/4644 96/10654 7.077639807741645e-26 1.323990486701537e-24 4.688625949830255e-25 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/79902/3796/5519/81565/91687/11243/83540/7514/54820/6396/64946/9793/140735/220134/4928/5903/55055/80776/1783/401541/79172/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/55166/79003/5527/701/57551 90 Human_papillomavirus_type_16 R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 90/4644 96/10654 7.077639807741645e-26 1.323990486701537e-24 4.688625949830255e-25 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/79902/3796/5519/81565/91687/11243/83540/7514/54820/6396/64946/9793/140735/220134/4928/5903/55055/80776/1783/401541/79172/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/55166/79003/5527/701/57551 90 Human_papillomavirus_type_16 R-HSA-8878159 Transcriptional regulation by RUNX3 90/4644 96/10654 7.077639807741645e-26 1.323990486701537e-24 4.688625949830255e-25 5689/6046/5682/182/5705/6097/6696/5709/5695/9759/10413/4609/4089/22938/5711/1387/7005/4088/5683/5699/5702/9794/6932/7040/3845/5696/5691/7314/5718/8463/51176/2648/5700/5707/55534/3280/84441/865/83439/6714/9861/8850/5698/5692/5713/595/5710/7157/5719/6233/1029/864/5706/10046/5714/6934/5688/5687/5708/5704/7311/5694/4851/3676/57154/5684/5720/2309/1499/10018/5690/5717/9491/10197/64750/7316/10213/1026/5715/5701/5685/5686/2033/861/5716/25937/3516/5693/5721/4193 90 Human_papillomavirus_type_16 R-HSA-73894 DNA Repair 239/4644 334/10654 7.87945325642083e-26 1.4545885419418978e-24 5.1511107161089085e-25 2237/4436/83990/151987/5892/9156/2074/1763/7486/27343/4913/56852/10445/5982/11200/472/6613/7507/80198/3981/5431/5435/2140/9978/5433/85015/26277/10980/64421/4683/2965/25898/165918/84126/5439/10987/8900/8924/57599/2067/672/2967/6612/6117/7334/10973/10714/55666/54386/348654/83695/4437/55183/7314/51514/7014/6118/2176/25/5888/322/328/83444/51588/7518/51720/63967/404672/9557/5531/9636/86/5438/3978/11201/116028/2070/890/197342/9031/1643/7517/9656/84464/51455/2177/5985/29089/2068/7157/5984/4595/4255/6233/7158/6047/93973/55247/8607/7874/5884/5810/5424/2188/5886/57697/8451/8554/10450/8467/80010/124739/3838/5434/7516/100534599/5436/2956/7515/54107/7013/4292/7706/580/11073/5591/8450/4331/5425/641/5111/2966/6119/3364/22976/10524/5427/144715/1161/5889/55775/1642/5429/142/1111/2071/9682/55215/1069/7329/9246/79728/51426/2873/146956/7311/4968/23030/3980/60/5536/8533/5983/2175/10038/2547/79840/5432/51138/7528/56655/9318/11284/51750/1017/54962/25913/6917/5440/5893/2178/902/84164/5883/27339/5430/10111/57804/7320/7520/675/51548/545/5441/7336/2072/29086/54778/7316/6996/8314/5426/9100/10635/10459/7415/5395/7341/4798/5437/9937/65057/2033/8914/7398/23514/2968/5932/8930/2138/9025/2189/55120/2187/79184/56949/7156/5890/5887/9716/5599/5981/57461/1022/2139/8178/50813/5980/7508 239 Human_papillomavirus_type_16 R-HSA-3858494 Beta-catenin independent WNT signaling 124/4644 146/10654 2.5879968755725615e-25 4.715531969387407e-24 1.6699036572388918e-24 2788/5689/2780/5579/5682/5331/5578/1212/5582/27327/143471/5705/5530/5709/5695/5881/5711/5683/5699/2782/5702/192669/1855/6932/163/4343/5593/3845/5696/5691/4920/7314/5879/2787/5718/51176/161/51701/5700/122706/5707/1856/8322/23198/10681/7471/83439/2792/9861/5698/5880/5692/5713/2785/2783/23002/2784/5710/5719/6233/7474/1857/1213/1211/1175/26523/801/2791/805/1173/144165/4772/409/5706/160/5714/6934/5688/5687/5708/2786/5704/7311/387/5694/57154/27161/815/5684/5720/54331/6885/1499/59345/5690/5532/57690/5717/9491/50855/51764/94235/10197/192670/64750/7316/10213/55970/5216/5715/5701/2793/5685/5686/5534/23112/23513/5716/808/5693/5721/6259/2790/5592 124 Human_papillomavirus_type_16 R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72/4644 73/10654 3.3236565075260445e-25 5.9386168673057255e-24 2.1030327203873673e-24 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/5716/701/5693/5721 72 Human_papillomavirus_type_16 R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 88/4644 94/10654 3.3439111369718626e-25 5.9386168673057255e-24 2.1030327203873673e-24 114791/10844/440145/7531/11190/203068/54801/51807/79441/10381/5116/5048/8655/9702/7846/7840/11064/81027/5518/55835/29922/23332/93323/79861/1454/983/79959/80097/10376/10540/85378/54930/54820/1453/27229/9793/84617/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/9738/1639/55722/4957/5566/7283/347733/22919/10426/22994/1069/5577/10383/5347/84790/80184/22897/5108/7280/10806/1778/115106/4926/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 88 Human_papillomavirus_type_16 R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 147/4644 182/10654 3.613369490754855e-25 6.336946744411327e-24 2.2440926311003838e-24 1912/23165/7068/7486/9112/6045/9212/80012/10274/348995/6613/57122/7181/23511/28996/4792/3190/9759/9612/8856/1911/9994/6790/6672/23279/1387/1789/23225/23512/165918/57332/7022/7067/7428/1107/5371/8924/672/115426/9972/10499/6612/5914/8021/6117/11315/55746/7421/4286/10062/7150/6670/83746/3622/1788/51564/51588/7518/3619/7153/2516/8517/332/10762/5465/1655/5970/2099/79902/9656/9883/84733/3066/7157/7158/10155/9063/7155/6396/129401/7703/4791/6015/8554/7020/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/493861/5111/4927/10521/1616/2908/8243/142/9971/1069/8086/7329/367/25942/9641/648/23468/5905/81929/5893/1487/55143/9631/5468/7021/8204/3090/79023/23636/10735/3183/4306/53371/6996/23137/9688/7341/2033/9126/3065/23314/6256/5987/6294/8648/6304/8480/10891/7508/4193 147 Human_papillomavirus_type_16 R-HSA-5607764 CLEC7A (Dectin-1) signaling 93/4644 101/10654 4.0660391137184574e-25 7.042781329070365e-24 2.4940486831385475e-24 8454/5689/4790/5682/7321/29108/143471/5705/5530/5709/5695/4792/5711/5683/5699/5702/7334/3551/5696/5691/7314/257397/5718/8945/4773/5700/122706/5707/5336/23198/23118/10892/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/801/4791/805/5170/4772/4775/5706/64581/6850/8915/5714/5688/5687/5708/7189/5704/7311/5971/5694/997/1147/5684/5720/6885/84433/5690/3553/5532/5717/9491/6500/10197/7316/10213/10768/7322/5715/5701/23291/5685/5686/5534/5716/808/5693/5721 93 Human_papillomavirus_type_16 R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 71/4644 72/10654 7.586745654887493e-25 1.2671671611675182e-23 4.4873984324647826e-24 5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 71 Human_papillomavirus_type_16 R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 71/4644 72/10654 7.586745654887493e-25 1.2671671611675182e-23 4.4873984324647826e-24 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 71 Human_papillomavirus_type_16 R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 71/4644 72/10654 7.586745654887493e-25 1.2671671611675182e-23 4.4873984324647826e-24 5689/9134/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/990/5699/5702/8900/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/898/890/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/1017/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 71 Human_papillomavirus_type_16 R-HSA-68949 Orc1 removal from chromatin 70/4644 71/10654 1.7312467926828285e-24 2.857575588392951e-23 1.0119485896548547e-23 8454/5689/5682/143471/5705/5709/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/890/9861/6502/5698/5692/5713/4175/5710/5719/6233/4999/4172/5000/4173/5706/5714/5688/5687/5708/81620/5704/23595/7311/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 70 Human_papillomavirus_type_16 R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 83/4644 88/10654 1.8785525071193338e-24 3.0646618226609593e-23 1.085283700563434e-23 5393/5689/5682/23404/5578/26986/143471/5705/5709/5695/5711/1432/5683/5699/5702/11340/8021/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/7534/9261/9861/5698/5692/5713/1981/5710/5719/6233/5580/7514/5600/8570/23016/118460/1994/5073/3842/3315/5706/7538/5714/5688/5687/5708/5704/7311/51010/5694/56915/3304/6418/167227/7529/22894/5684/5720/207/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/51013/5716/54464/5693/54512/5721 83 Human_papillomavirus_type_16 R-HSA-927802 Nonsense-Mediated Decay (NMD) 102/4644 115/10654 3.11772701543237e-24 4.9706488666495626e-23 1.760247788617319e-23 6158/9887/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/65109/6173/6167/6156/6143/5520/6139/23381/5518/3921/6208/6170/5515/6203/6147/6222/26019/2935/6134/22794/6155/4116/6231/6142/23521/1981/6207/6233/6188/23049/5976/6122/6230/6194/2107/6166/6136/6125/6232/6160/55110/6193/6210/6229/6205/140801/6235/6181/9939/7311/6223/25873/9045/6187/6168/22916/6157/6137/10921/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/4686/6209/11224/6130/6204/6228/6124/6189/23293/9775/6135/6201/6161/6133 102 Human_papillomavirus_type_16 R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 102/4644 115/10654 3.11772701543237e-24 4.9706488666495626e-23 1.760247788617319e-23 6158/9887/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/65109/6173/6167/6156/6143/5520/6139/23381/5518/3921/6208/6170/5515/6203/6147/6222/26019/2935/6134/22794/6155/4116/6231/6142/23521/1981/6207/6233/6188/23049/5976/6122/6230/6194/2107/6166/6136/6125/6232/6160/55110/6193/6210/6229/6205/140801/6235/6181/9939/7311/6223/25873/9045/6187/6168/22916/6157/6137/10921/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/4686/6209/11224/6130/6204/6228/6124/6189/23293/9775/6135/6201/6161/6133 102 Human_papillomavirus_type_16 R-HSA-8878166 Transcriptional regulation by RUNX2 106/4644 121/10654 3.893707756159114e-24 6.138058406619366e-23 2.173660627920877e-23 8454/8493/5689/7291/5682/5925/143471/5705/5709/9978/5695/9759/10413/4089/5711/5683/5699/5702/5696/5691/7314/5718/25/6662/5700/122706/5707/5594/3280/23198/10013/632/2737/865/11059/983/6714/2099/9861/2932/6502/5698/10000/5692/5713/595/5710/5719/6233/7525/10432/117581/1019/3958/5706/1277/891/579/5714/6772/2736/5688/5687/4322/2908/5708/208/5704/23493/7311/367/860/1750/5694/5595/57154/5684/8841/5720/23462/10273/207/5690/5717/9491/6500/4086/10197/7316/10213/4094/1026/5715/5701/5685/5686/55294/23314/861/25925/5716/25937/581/5693/5721/10891 106 Human_papillomavirus_type_16 R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 79/4644 83/10654 4.42808834237166e-24 6.902897715941599e-23 2.4445119270168697e-23 8454/5689/4893/4790/5579/5682/143471/5705/5530/5709/5695/4792/5711/5683/5699/5702/4794/3845/3265/3551/5696/5691/7314/5718/8945/4773/5966/5700/122706/5707/23198/10892/8517/5970/9861/5698/5692/5713/5710/5478/5719/6233/801/805/4772/4775/5706/8915/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/84433/5690/5532/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5534/5716/808/5693/5721 79 Human_papillomavirus_type_16 R-HSA-2990846 SUMOylation 149/4644 188/10654 6.753648164687393e-24 1.041249271984221e-22 3.687359090494448e-23 1912/10054/23165/7068/7486/9112/6045/9212/80012/10274/348995/6613/57122/7181/23511/28996/4792/3190/9759/9612/8856/1911/9994/6790/6672/23279/1387/1789/23225/23512/165918/57332/7022/7067/7428/1107/5371/8924/672/115426/9972/10499/6612/5914/8021/6117/11315/55746/7421/4286/10062/7150/6670/83746/3622/1788/51564/51588/7518/3619/7153/2516/8517/332/10762/5465/1655/5970/2099/79902/9656/9883/84733/3066/7157/7158/10155/9063/7155/6396/129401/7703/4791/6015/8554/7020/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/493861/5111/4927/10521/1616/2908/8243/142/9971/1069/8086/7329/367/25942/9641/648/23468/5905/81929/5893/29843/1487/55143/9631/5468/7021/8204/3090/79023/23636/10735/3183/4306/53371/6996/23137/9688/7341/2033/9126/3065/23314/6256/5987/6294/8648/6304/8480/10891/7508/4193 149 Human_papillomavirus_type_16 R-HSA-8854518 AURKA Activation by TPX2 71/4644 73/10654 1.5892641038620995e-23 2.4117253231257524e-22 8.540603612674759e-23 7531/11190/203068/54801/79441/5116/5048/8655/6790/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/22974/3161/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 71 Human_papillomavirus_type_16 R-HSA-5687128 MAPK6/MAPK4 signaling 83/4644 89/10654 1.5986490024996078e-23 2.4117253231257524e-22 8.540603612674759e-23 2308/5689/2118/3725/5682/27327/143471/5705/5709/5695/4609/5711/5683/5699/5702/192669/8997/4343/5062/5696/5691/7314/5879/5718/5700/122706/5707/5567/23198/3337/983/9861/5698/5692/5713/5710/8555/896/5719/6233/7514/26523/5568/3315/5706/5597/5714/5566/5688/5687/5708/5063/998/5704/7311/5694/5058/27161/5684/5720/2309/10642/5690/57690/5717/9491/10197/192670/5596/8550/7316/10213/5715/5701/5685/5686/8556/23112/5716/5896/8202/5693/5721 83 Human_papillomavirus_type_16 R-HSA-68867 Assembly of the pre-replicative complex 67/4644 68/10654 2.0531960037573696e-23 3.0645042481612655e-22 1.085227898962462e-22 5689/5682/143471/5705/5709/1869/4174/5695/84515/4998/5711/5683/990/5699/5702/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/9861/5698/5692/5713/4175/5710/5719/6233/4999/4172/5000/4173/5706/5714/51053/5688/5687/5708/81620/1870/5704/23595/7311/5694/4176/5684/5720/5690/5717/9491/10197/7316/10213/4171/1871/5715/5701/5685/5686/5716/5693/5721 67 Human_papillomavirus_type_16 R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 87/4644 95/10654 3.809739969741164e-23 5.626384397417741e-22 1.992462344285684e-22 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/6208/6170/6203/6147/6222/2935/6134/6155/6231/6142/23521/1981/6207/6233/6188/5976/6122/6230/6194/2107/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/22916/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/4686/6209/11224/6130/6204/6228/6124/6189/6135/6201/6161/6133 87 Human_papillomavirus_type_16 R-HSA-1169091 Activation of NF-kappaB in B cells 66/4644 67/10654 4.6791425541088757e-23 6.7678731993966525e-22 2.3966959148555505e-22 8454/5689/4790/5579/5682/143471/5705/5709/5695/4792/5711/5683/5699/5702/4794/3551/5696/5691/7314/5718/8945/5966/5700/122706/5707/23198/10892/8517/5970/9861/5698/5692/5713/5710/5719/6233/5706/8915/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/84433/5690/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5716/5693/5721 66 Human_papillomavirus_type_16 R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 66/4644 67/10654 4.6791425541088757e-23 6.7678731993966525e-22 2.3966959148555505e-22 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 66 Human_papillomavirus_type_16 R-HSA-5696398 Nucleotide Excision Repair 98/4644 111/10654 5.572137117050876e-23 7.9772534441044675e-22 2.8249717714801434e-22 2074/10445/5982/6613/7507/5431/5435/9978/5433/85015/10980/2965/5439/10987/2067/2967/6612/6117/7334/10714/7314/6118/83444/404672/9557/86/5438/3978/1643/5985/2068/5984/6233/93973/8607/7874/5424/5886/8451/8554/10450/5434/100534599/5436/7515/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/142/2071/1069/7329/51426/2873/7311/3980/60/8533/5983/10038/5432/51138/7528/56655/9318/6917/5440/902/27339/5430/57804/5441/7336/2072/54778/7316/5426/7341/4798/5437/2033/2968/56949/5887/9716/5981/57461/1022/8178/50813/7508 98 Human_papillomavirus_type_16 R-HSA-156842 Eukaryotic Translation Elongation 85/4644 93/10654 1.716065285553136e-22 2.4319591875061107e-21 8.612257467103458e-22 6158/6138/6227/6206/6234/6191/6128/6132/6129/1915/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/6122/6230/6194/6166/1938/6136/6125/1937/6232/6160/1933/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/1936/6152/51065/6141/6164/6209/11224/6130/6204/6228/6124/6189/6135/6201/6161/6133 85 Human_papillomavirus_type_16 R-HSA-9020702 Interleukin-1 signaling 92/4644 103/10654 1.7576681833463904e-22 2.4660084612349857e-21 8.732835605678909e-22 8454/5689/4790/5682/8878/143471/5705/5709/9978/5695/4792/5711/5683/5699/5702/3654/7334/3551/5696/5691/7314/257397/5718/8945/1326/11213/5700/122706/5707/8767/23198/23118/8517/5970/9861/5698/5692/5713/5710/10454/5719/6233/7850/5608/4791/3557/351/5706/79155/5714/64127/3552/5688/5687/5708/3656/57162/7189/5704/7311/5694/6416/3554/1147/5684/5720/6885/5604/4215/10392/5690/3553/5717/9491/6500/10197/4615/7316/10213/4793/3146/5715/5701/23291/5685/5686/6288/6285/5716/57161/5693/5721 92 Human_papillomavirus_type_16 R-HSA-380259 Loss of Nlp from mitotic centrosomes 68/4644 70/10654 1.8094481211369333e-22 2.4888781509363896e-21 8.813823665393524e-22 7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 68 Human_papillomavirus_type_16 R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 68/4644 70/10654 1.8094481211369333e-22 2.4888781509363896e-21 8.813823665393524e-22 7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 68 Human_papillomavirus_type_16 R-HSA-195253 Degradation of beta-catenin by the destruction complex 77/4644 82/10654 2.0243330046583507e-22 2.7574167044035593e-21 9.764794871729603e-22 8454/5689/5682/5526/1452/143471/5705/5709/9978/5695/5711/5683/324/5699/8312/5702/6932/5518/5696/5691/7314/5515/5718/51176/8945/5700/122706/5707/23198/5528/7091/83439/9861/5519/2932/5698/5692/5713/5710/5719/6233/7089/7090/5706/5714/6934/5688/5687/5708/5529/7088/5704/7311/5694/5516/5684/5720/1487/1499/5525/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/3065/5527/1488/5716/5693/5721 77 Human_papillomavirus_type_16 R-HSA-156902 Peptide chain elongation 82/4644 89/10654 2.520565426429714e-22 3.4003397050777774e-21 1.2041567624239119e-21 6158/6138/6227/6206/6234/6191/6128/6132/6129/1915/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/6122/6230/6194/6166/1938/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/6209/11224/6130/6204/6228/6124/6189/6135/6201/6161/6133 82 Human_papillomavirus_type_16 R-HSA-162587 HIV Life Cycle 124/4644 152/10654 3.7997401753581586e-22 5.077176634311902e-21 1.797972293502808e-21 6884/23165/6875/2237/7852/27243/6874/348995/57122/3981/5431/23511/5435/5433/2960/23279/23327/29082/23225/2965/5439/6873/3836/9972/6881/2967/51616/8021/11198/904/51497/55746/7314/25978/2959/7518/404672/10015/5438/3978/10762/51534/4836/9397/79902/9883/83860/51510/2068/5902/5478/6233/7514/1025/6396/129401/6883/7936/6829/2957/25920/4928/2963/5434/5903/55706/7175/5436/6878/920/4331/4927/8148/2966/2962/54457/8812/128866/905/2071/5901/8086/7311/6880/6908/7251/1104/2547/6882/2961/5432/22916/1234/6877/5905/6917/81929/5440/902/9631/3159/5430/7520/6749/79023/5441/23636/7469/4686/7316/6872/53371/9688/6879/9150/9525/5437/8815/6827/2968/138474/1022/8178/8480 124 Human_papillomavirus_type_16 R-HSA-2219528 PI3K/AKT Signaling in Cancer 90/4644 101/10654 7.538563476320115e-22 9.977928827619926e-21 3.5334676870139965e-21 5295/2308/374/2250/5291/7039/3082/941/2064/145957/2534/9965/2264/9542/2885/2475/8660/2252/2253/5879/1839/5290/3667/8823/2065/3815/2069/7249/2260/2249/6714/2099/2248/2932/2247/5880/10000/7409/2246/2251/5154/3932/2931/255324/5781/940/5170/4303/930/6199/2263/4233/8503/5159/29851/3084/208/10718/79109/5293/1956/2549/1147/8822/685/2309/842/207/1027/8817/2100/2254/1950/1026/26281/10818/2261/2255/3164/391/5728/2066/27006/942/1385/5155/4254/5296/5156/4193 90 Human_papillomavirus_type_16 R-HSA-69615 G1/S DNA Damage Checkpoints 66/4644 68/10654 9.133537871570997e-22 1.1976031433471129e-20 4.2410525089832866e-021 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/993/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/1111/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 66 Human_papillomavirus_type_16 R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 62/4644 63/10654 1.257756955059837e-21 1.6339194518045846e-20 5.786172346863968e-21 5689/11065/5682/7321/8697/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/5707/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 62 Human_papillomavirus_type_16 R-HSA-166166 MyD88-independent TLR4 cascade 88/4644 99/10654 3.2165227197308847e-21 4.102528523438574e-20 1.452821745179883e-20 8454/3725/9252/4790/7321/4792/1432/929/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/1326/5601/5606/8737/8767/1849/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/3665/351/330/79155/7867/64127/5602/3656/7189/7311/9641/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/7316/4205/4793/3146/7322/329/23291/6288/2002/6285/5609/1385/5599/353376/148022 88 Human_papillomavirus_type_16 R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 88/4644 99/10654 3.2165227197308847e-21 4.102528523438574e-20 1.452821745179883e-20 8454/3725/9252/4790/7321/4792/1432/929/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/1326/5601/5606/8737/8767/1849/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/3665/351/330/79155/7867/64127/5602/3656/7189/7311/9641/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/7316/4205/4793/3146/7322/329/23291/6288/2002/6285/5609/1385/5599/353376/148022 88 Human_papillomavirus_type_16 R-HSA-2871837 FCERI mediated NF-kB activation 76/4644 82/10654 3.45285848561154e-21 4.3642886984801717e-20 1.5455184496999972e-20 8454/5689/4790/5682/7321/143471/5705/5709/5695/4792/5711/5683/5699/5702/7334/3551/5696/5691/7314/257397/5718/8945/5700/122706/5707/23198/23118/10892/8517/5970/9861/5588/5698/5692/5713/5710/10454/5719/6233/5170/2205/5706/2206/8915/5714/5688/5687/4067/5708/7189/5704/7311/5694/997/1147/5684/5720/6885/84433/5690/5717/9491/6500/10197/7316/10213/7322/5715/5701/23291/5685/5686/5716/5693/5721/2207 76 Human_papillomavirus_type_16 R-HSA-69563 p53-Dependent G1 DNA Damage Response 64/4644 66/10654 4.6001442003437505e-21 5.711506471754232e-20 2.0226064858521196e-20 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Human_papillomavirus_type_16 R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 64/4644 66/10654 4.6001442003437505e-21 5.711506471754232e-20 2.0226064858521196e-20 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Human_papillomavirus_type_16 R-HSA-199418 Negative regulation of the PI3K/AKT network 95/4644 110/10654 8.978845466145147e-21 1.1050280867545298e-19 3.9132179686246625e-20 5295/374/2250/5291/5526/7039/3082/941/2064/145957/2534/9965/2264/3630/3654/9542/2885/8660/5518/2252/2253/5879/5515/23396/1839/5290/3667/8823/90865/2065/3815/5594/2069/57761/2260/5528/2249/6714/2099/2248/5519/2247/5880/10000/7409/2246/2251/5154/3932/8394/255324/5781/940/23239/930/2263/4233/8503/5159/29851/3084/5529/7189/208/10718/5293/1956/2549/5595/5516/8822/685/5305/5525/8870/207/8817/4615/2100/2254/1950/26281/10818/2261/2255/391/5728/2066/27006/942/5527/5155/4254/5296/5156 95 Human_papillomavirus_type_16 R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 72/4644 77/10654 9.759543410781146e-21 1.1906642961152997e-19 4.2164800822779874e-20 5689/5682/51807/63943/143471/10381/5705/5709/5695/5711/7846/5683/5699/5702/81027/5696/5691/7314/5718/79861/5700/122706/5707/23198/983/9861/5698/5692/5713/10376/5710/7157/5719/6233/84617/51512/10382/7277/5706/9133/891/5714/5688/5687/347733/5708/22919/5704/3326/7311/10383/5347/84790/5694/7280/5684/5720/5690/5717/9491/10197/7316/10213/1026/5715/5701/5685/3320/5686/5716/5693/5721 72 Human_papillomavirus_type_16 R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 84/4644 94/10654 1.162570543425642e-20 1.4061090279535998e-19 4.9794310026942205e-20 8454/3725/9252/4790/7321/4792/1432/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/1326/5601/5606/8737/8767/1849/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5608/4791/3665/351/330/7098/79155/7867/64127/5602/3656/7189/7311/9641/6416/5595/5516/1147/1845/6885/5604/10392/6500/7316/4205/4793/3146/7322/329/23291/6288/2002/6285/5609/1385/5599/148022 84 Human_papillomavirus_type_16 R-HSA-909733 Interferon alpha/beta signaling 66/4644 69/10654 1.2061059986037737e-20 1.446296338496662e-19 5.1217456710839513e-20 3443/5777/5770/3107/9021/3662/3106/4599/684/3133/3429/91543/4938/5696/3445/10410/9636/2634/3444/103/3434/3433/3451/3448/3661/3439/10581/3452/4940/3437/6773/7297/5781/3430/3660/3446/3135/3665/10379/3455/4600/8638/3394/3663/6772/8651/3659/25939/3440/3454/3716/3456/3105/3441/51447/54739/2537/3449/8519/3664/6041/1958/4939/6059/3669/3134 66 Human_papillomavirus_type_16 R-HSA-373076 Class A/1 (Rhodopsin-like receptors) 229/4644 335/10654 1.3729569869236947e-20 1.6324225869948674e-19 5.780871523889241e-20 729230/2532/4160/10316/2149/1880/3972/1816/7852/10161/83551/3363/338442/155/64805/1237/5734/3354/2841/4987/51289/3360/3060/6349/3576/6360/4985/2920/2921/1236/6010/554/2840/2831/5367/4988/6370/58191/153/6755/1524/1081/643/4161/185/339403/8843/2847/2833/6347/9290/9170/187/6750/2587/53829/6387/4544/4543/10663/4889/9283/727/122042/1909/5732/117579/3579/2492/23566/2358/319100/5179/27202/6367/8811/1812/56923/2832/27199/2826/6376/165140/27198/5443/6354/3627/3361/6346/151306/134864/134/9034/59350/2863/1129/51554/51083/2829/1233/6366/1241/2861/728/183/10022/170589/6373/57121/5731/1132/1814/3362/6357/4159/8698/9934/2151/6869/6361/1813/50865/10803/351/11251/3352/8484/6351/4158/6863/6752/1903/84539/6753/3577/594857/4157/5368/6754/6915/8862/301/5032/56670/150/2853/6751/5020/186/53637/10563/5540/1901/5733/256933/7252/5729/10850/624/4852/9287/134860/5473/4283/1910/11255/122876/10874/6356/611/56477/387129/3350/129521/1234/151/57007/9294/1128/283869/4986/6374/2488/5539/136/2852/1230/4886/2919/5196/3827/5173/2357/6352/140/6348/9038/152/1906/6364/7253/5030/5697/3640/3355/3351/6288/6372/5739/3973/719/6363/1268/2359/2846/5660/1815/1325/1232/1902/551/154/1269/3274/59340/5724/4887/718/623 229 Human_papillomavirus_type_16 R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 59/4644 60/10654 1.4790868114831287e-20 1.700949833205598e-19 6.023545944952863e-20 8454/5689/9134/5682/5705/5709/5753/5695/5711/5683/5699/5702/8900/5696/5691/7314/5718/5700/5707/898/890/9861/6502/5698/5692/5713/595/5710/5719/6233/1163/1019/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/5690/5717/1027/9491/6500/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721 59 Human_papillomavirus_type_16 R-HSA-5610780 Degradation of GLI1 by the proteasome 59/4644 60/10654 1.4790868114831287e-20 1.700949833205598e-19 6.023545944952863e-20 8454/5689/5682/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/83737/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/8650/9861/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/2735/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Human_papillomavirus_type_16 R-HSA-5610783 Degradation of GLI2 by the proteasome 59/4644 60/10654 1.4790868114831287e-20 1.700949833205598e-19 6.023545944952863e-20 8454/5689/5682/1452/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/9861/2932/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/2736/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Human_papillomavirus_type_16 R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 59/4644 60/10654 1.4790868114831287e-20 1.700949833205598e-19 6.023545944952863e-20 8454/5689/5682/1452/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/2737/9861/2932/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Human_papillomavirus_type_16 R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 90/4644 103/10654 1.6708399439134654e-20 1.9058442612281235e-19 6.749135246274332e-20 5295/374/2250/5291/5526/7039/3082/941/2064/145957/2534/9965/2264/3630/3654/9542/2885/8660/5518/2252/2253/5879/5515/23396/1839/5290/3667/8823/90865/2065/3815/5594/2069/2260/5528/2249/6714/2099/2248/5519/2247/5880/7409/2246/2251/5154/3932/8394/255324/5781/940/930/2263/4233/8503/5159/29851/3084/5529/7189/10718/5293/1956/2549/5595/5516/8822/685/5305/5525/8870/207/8817/4615/2100/2254/1950/26281/10818/2261/2255/391/2066/27006/942/5527/5155/4254/5296/5156 90 Human_papillomavirus_type_16 R-HSA-983705 Signaling by the B Cell Receptor (BCR) 96/4644 112/10654 1.796081677159533e-20 2.0321795105280846e-19 7.196524207294564e-20 5295/8454/5689/5777/4893/4790/5579/5682/143471/5705/5530/5709/5695/4792/5711/5683/2534/5699/5702/30011/2885/4794/3845/3265/3551/5696/5691/7314/6786/5718/8945/4773/5966/5700/122706/5707/5336/23198/10892/8517/5970/9861/5698/5692/5713/5710/5478/5719/6233/7409/801/805/4772/4775/930/5706/6850/8915/5714/5688/5687/4067/5708/695/6654/5704/7311/5293/5694/1147/5684/5720/6885/4690/640/84433/5690/5532/5717/9491/6500/10197/7316/10213/10768/4793/5715/5701/23291/5685/5686/5534/5716/808/5693/5721 96 Human_papillomavirus_type_16 R-HSA-195258 RHO GTPase Effectors 224/4644 327/10654 2.4360992432135884e-20 2.7342777905829316e-19 9.682853413025801e-20 55839/11130/64837/71/6249/51517/5579/9735/7531/5526/51807/10971/5578/9212/388/7533/2810/147841/147179/348995/10381/57122/6280/1780/23122/3688/5048/57405/8655/10094/23279/1432/2017/2491/7846/23081/79784/9475/1060/81027/4628/11004/8976/1855/2885/23433/6093/9184/8826/10499/5518/23332/25909/3071/10726/81930/5062/55746/5879/5515/26999/25/79682/1072/10403/79861/4638/25936/4659/10093/1856/10006/4771/389/5594/3619/64105/7534/332/5528/6714/79902/3796/5519/81565/999/89953/10810/5880/91687/11243/10376/23002/83540/5580/1857/128239/9055/23191/7514/54820/29984/1729/6396/1535/5600/801/64946/9793/10109/5586/140735/5500/10787/4221/805/220134/5170/84617/4928/5590/114793/5903/55055/5747/80776/1783/401541/2316/7532/10382/10627/79172/7277/79980/6232/5501/10152/6279/54821/10092/9183/10163/1062/699/347733/22919/55845/5063/3895/5529/51143/998/695/10788/10097/57120/367/10383/5347/387/60/84790/84643/5058/7280/7529/5595/64130/1778/5516/5905/81929/3984/54908/55143/1495/1499/5525/4690/1058/991/79019/4627/348235/80152/10458/1063/3985/8379/1027/1080/23421/55920/79023/6242/1781/10398/4085/5289/5585/5216/10552/81624/55166/8936/4637/995/79003/391/23028/1742/5527/10096/7454/701/23380/9928/3799/103910/57551/5300/808/10095 224 Human_papillomavirus_type_16 R-HSA-446652 Interleukin-1 family signaling 114/4644 140/10654 2.459923506736129e-20 2.739105301548245e-19 9.699948998992925e-20 8454/834/5689/5777/4790/5682/26469/5783/27178/8878/143471/5705/5709/9978/5695/4792/3606/5711/4088/5683/5699/5702/3654/7334/3551/5696/5691/7314/3596/257397/5718/8945/1326/90865/11213/5700/122706/5707/8767/29110/23198/23118/8517/3565/5970/8809/9861/5698/5692/5713/5710/10454/5719/6233/7850/5781/5608/4791/3557/56300/351/5782/5706/79155/6774/5714/64127/3552/5688/5687/5708/3656/57162/5771/7189/5704/84639/7311/240/5694/6416/3554/1147/5778/5684/5720/6885/5604/4215/10392/5690/3553/5717/9491/6500/25930/10197/4615/7316/10213/4793/3146/5715/5701/23291/5685/5686/6288/6285/5716/5599/57161/5693/5721 114 Human_papillomavirus_type_16 R-HSA-4420097 VEGFA-VEGFR2 Pathway 87/4644 99/10654 3.1384027027983336e-20 3.467070072461466e-19 1.2277878787574088e-19 5295/4893/857/5335/71/5579/5291/5578/1432/2534/9475/3690/5603/2475/6093/8440/9564/3845/3265/3071/5062/5829/5879/26999/5290/5567/10006/57761/5921/1500/9261/6714/10810/10000/3728/7410/5580/7409/23191/3685/3791/1535/5600/6300/801/10787/805/5170/5590/6461/5747/5568/3315/10451/1793/10152/7867/5566/1003/10163/55845/5063/998/208/79109/2185/387/60/5058/63916/25759/558/1495/1499/4690/207/7422/10458/9047/10768/8936/3320/4846/1398/9844/5296/808 87 Human_papillomavirus_type_16 R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 58/4644 59/10654 3.3608950751600606e-20 3.6838560862887227e-19 1.30455795680555e-19 5689/5682/143471/5705/5709/5695/84515/4998/5711/5683/990/5699/5702/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/4999/5000/5706/5714/51053/5688/5687/5708/81620/5704/23595/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 58 Human_papillomavirus_type_16 R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 73/4644 79/10654 3.4038324754943467e-20 3.7019976458283473e-19 1.3109823977424167e-19 2074/5982/7507/5431/5435/9978/5433/10980/2965/5439/10987/2067/2967/6117/10714/7314/6118/404672/5438/3978/5985/2068/5984/6233/7874/5424/8451/10450/5434/100534599/5436/7515/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/2071/51426/2873/7311/3980/8533/5983/5432/51138/56655/9318/6917/5440/902/27339/5430/57804/5441/2072/7316/5426/5437/2033/2968/56949/9716/5981/57461/1022/8178/50813 73 Human_papillomavirus_type_16 R-HSA-192823 Viral mRNA Translation 80/4644 89/10654 4.1112323106215846e-20 4.4369684090785255e-19 1.5712563972578041e-19 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/6209/11224/6130/6204/6228/6124/6189/6135/6201/6161/6133 80 Human_papillomavirus_type_16 R-HSA-9013694 Signaling by NOTCH4 75/4644 82/10654 4.982693264009099e-20 5.336426449927301e-19 1.889780008527356e-19 8454/5689/5682/182/23385/5705/5709/9978/5695/22938/5711/1387/4088/5683/5699/4853/5702/9794/5696/5691/7314/5718/2648/5700/5707/55534/3280/84441/7534/102/9861/8850/5698/5692/5713/5710/5719/6233/2324/5663/5706/10460/10046/5714/5688/5687/5708/59/4855/5704/23493/7311/5694/4851/5684/5720/23462/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/2033/55294/5716/3516/5693/5721 75 Human_papillomavirus_type_16 R-HSA-5685942 HDR through Homologous Recombination (HRR) 64/4644 67/10654 5.899574910222487e-20 6.270533029577386e-19 2.2205736504186715e-19 83990/5892/9156/1763/7486/5982/472/80198/4683/84126/672/6117/10714/348654/83695/7314/6118/5888/116028/197342/7517/84464/5985/5984/6233/5884/5810/5424/80010/7516/54107/580/11073/5425/641/5111/6119/3364/10524/5427/144715/5889/5429/1111/79728/51426/146956/7311/5983/56655/51750/5883/10111/57804/675/545/7316/5426/10635/23514/5932/7156/5890/5981 64 Human_papillomavirus_type_16 R-HSA-194138 Signaling by VEGF 92/4644 107/10654 7.196747520930853e-20 7.591756971327809e-19 2.688456533343382e-19 5295/4893/857/5335/71/5579/5291/5578/8829/7423/1432/2534/9475/3690/5603/2475/6093/8440/9564/3845/3265/3071/5062/5829/5879/26999/5290/5567/10006/57761/5921/1500/9261/6714/10810/10000/3728/7410/5580/2324/7409/23191/3685/3791/1535/5600/6300/801/10787/805/5170/5590/6461/5747/7424/5568/3315/10451/1793/10152/7867/5566/1003/10163/55845/5063/998/208/79109/2185/387/60/5058/63916/25759/558/1495/1499/4690/207/7422/10458/9047/10768/8936/3320/4846/1398/9844/5228/5296/808 92 Human_papillomavirus_type_16 R-HSA-9009391 Extra-nuclear estrogen signaling 71/4644 77/10654 1.5561994749564652e-19 1.629364077137254e-18 5.770040472737248e-19 5295/2788/374/4893/857/2770/7039/2782/3845/3265/2773/2787/1839/5290/4316/5594/2069/10681/4313/2792/6714/2099/10000/2785/595/2783/2784/2771/7514/2353/255324/801/2791/805/5170/5590/6464/5747/1903/3315/4318/8503/2786/208/1956/858/3480/5595/596/685/54331/2309/59345/207/1027/51764/94235/2100/1950/55970/4314/346562/2793/3320/4846/2002/1385/5296/808/3276/2790 71 Human_papillomavirus_type_16 R-HSA-5621481 C-type lectin receptors (CLRs) 114/4644 142/10654 2.1438781112773035e-19 2.2280451778681903e-18 7.890140105441617e-19 8454/5689/4586/9252/4893/4790/5682/7321/29108/143471/5705/5530/5709/5695/4792/5711/1387/5683/2534/5699/5702/5894/3845/7334/3265/3551/5062/5696/5691/7314/257397/5718/8945/4773/5700/122706/5707/5567/5336/4582/23198/23118/10892/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/801/4791/805/5170/4772/5568/4775/5706/64581/6850/8915/5714/5566/5688/5687/4067/5708/5063/7189/5704/30835/7311/5971/4585/5694/5058/997/1147/5684/5720/6885/84433/5690/3553/5532/5717/9491/6500/10197/7316/10213/94025/10768/7322/5715/5701/23291/5685/5686/2033/5534/5716/808/5693/5721/2207 114 Human_papillomavirus_type_16 R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 73/4644 80/10654 2.2327806970268715e-19 2.303375969065221e-18 8.156907809571853e-19 3839/23165/5335/348995/57122/23511/4734/23279/8672/23225/1973/3836/4599/9972/8021/7334/4938/55746/7314/402569/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/1977/51191/6233/5610/4940/6396/129401/4928/3838/5903/55706/7175/2316/4600/8638/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/1974/5595/3837/81929/9631/79023/23636/7316/53371/9688/6041/4939/6059/5300/9775/5495/8480 73 Human_papillomavirus_type_16 R-HSA-72764 Eukaryotic Translation Termination 82/4644 93/10654 2.4169326419101214e-19 2.4751507274451828e-18 8.765210964130446e-19 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/6208/6170/6203/6147/6222/2935/6134/6155/6231/6142/23521/6207/6233/6188/6122/6230/6194/2107/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/6209/11224/6130/6204/6228/6124/6189/6135/6201/6161/6133 82 Human_papillomavirus_type_16 R-HSA-162599 Late Phase of HIV Life Cycle 112/4644 139/10654 2.599077515974412e-19 2.6423954745739855e-18 9.35747206361497e-19 6884/23165/6875/27243/6874/348995/57122/5431/23511/5435/5433/2960/23279/23327/29082/23225/2965/5439/6873/9972/6881/2967/51616/8021/11198/904/51497/55746/7314/25978/2959/404672/10015/5438/10762/51534/4836/9397/79902/9883/83860/51510/2068/5902/5478/6233/7514/1025/6396/129401/6883/7936/6829/2957/25920/4928/2963/5434/5903/55706/7175/5436/6878/4331/4927/8148/2966/2962/54457/8812/128866/905/2071/5901/8086/7311/6880/6908/7251/1104/6882/2961/5432/22916/6877/5905/6917/81929/5440/902/9631/5430/6749/79023/5441/23636/7469/4686/7316/6872/53371/9688/6879/9150/9525/5437/6827/2968/138474/1022/8178/8480 112 Human_papillomavirus_type_16 R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 62/4644 65/10654 2.8765576707014163e-19 2.9034607280533e-18 1.0281978194404154e-18 2074/5982/5431/5435/9978/5433/2965/5439/2967/6117/10714/7314/6118/404672/5438/3978/5985/2068/5984/6233/7874/5424/8451/10450/5434/100534599/5436/7515/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/2071/51426/7311/3980/5983/5432/56655/6917/5440/902/27339/5430/57804/5441/7316/5426/5437/2033/2968/56949/9716/5981/57461/1022 62 Human_papillomavirus_type_16 R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 55/4644 56/10654 3.933420160425351e-19 3.941848917911977e-18 1.3959205381359143e-18 5689/5682/26986/143471/5705/5709/5695/5711/5683/5699/5702/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/9861/5698/5692/5713/1981/5710/5719/6233/3315/5706/5714/5688/5687/5708/5704/7311/5694/3304/5684/5720/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 55 Human_papillomavirus_type_16 R-HSA-3371556 Cellular response to heat stress 79/4644 89/10654 4.373432163270904e-19 4.3517200887014746e-18 1.5410675483866122e-18 23165/6782/573/7531/1915/817/9530/348995/472/57122/3313/23511/3305/23279/1387/259217/23225/3309/9531/2475/3306/9972/23411/8021/6117/3312/55746/51182/818/3303/6118/5594/3308/10049/10013/3337/10762/9261/79902/9883/2932/6396/129401/3297/57521/4928/5903/55706/7175/1410/4927/6119/57805/3310/7266/816/8086/3326/3304/10728/5595/815/81929/9631/545/79023/23636/10808/53371/9532/9688/7415/3320/2033/6767/22824/9529/2288/8480 79 Human_papillomavirus_type_16 R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 58/4644 60/10654 5.793333472179206e-19 5.72397666300523e-18 2.0270225343725616e-18 8454/5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/5970/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 58 Human_papillomavirus_type_16 R-HSA-1234174 Cellular response to hypoxia 69/4644 75/10654 7.081267456594442e-19 6.899318223334723e-18 2.4432443271290764e-18 5689/5682/64344/7321/3091/143471/5705/5709/9978/5695/5711/1387/5683/5699/7428/5702/2056/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/405/768/112399/84962/5706/5714/10370/5688/5687/5708/5704/7311/2034/55662/5694/5684/5720/7422/5690/5717/9491/10197/7316/10213/7322/5715/5701/112398/5685/5686/2033/8453/5716/54583/5693/5721 69 Human_papillomavirus_type_16 R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 69/4644 75/10654 7.081267456594442e-19 6.899318223334723e-18 2.4432443271290764e-18 5295/374/2250/5291/7039/3082/941/2064/145957/2534/9965/2264/9542/2885/8660/2252/2253/5879/1839/5290/3667/8823/2065/3815/2069/2260/2249/6714/2099/2248/2247/5880/7409/2246/2251/5154/3932/255324/5781/940/930/2263/4233/8503/5159/29851/3084/10718/5293/1956/2549/8822/685/8817/2100/2254/1950/26281/10818/2261/2255/391/2066/27006/942/5155/4254/5296/5156 69 Human_papillomavirus_type_16 R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 54/4644 55/10654 8.922872939849914e-19 8.57451420178728e-18 3.0364787509799277e-18 8454/5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/26271/5706/5714/5688/5687/5708/5704/51343/7311/5694/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 54 Human_papillomavirus_type_16 R-HSA-8941858 Regulation of RUNX3 expression and activity 54/4644 55/10654 8.922872939849914e-19 8.57451420178728e-18 3.0364787509799277e-18 5689/5682/5705/5709/5695/5711/5683/5699/5702/7040/5696/5691/7314/5718/5700/5707/865/6714/9861/5698/5692/5713/5710/5719/6233/1029/864/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/2033/5716/5693/5721/4193 54 Human_papillomavirus_type_16 R-HSA-69481 G2/M Checkpoints 129/4644 168/10654 1.075395973114554e-18 1.0263813267208975e-17 3.634707478052772e-18 5689/83990/5682/9156/1763/7531/7486/10971/5982/7533/2810/11200/143471/472/5705/5709/4174/5695/84515/4998/5711/4683/10926/5683/990/165918/84126/5699/5702/8924/55388/672/6117/7334/5001/7465/5696/83695/5691/7314/5718/6118/23594/5700/122706/5707/51588/51720/23198/63967/7534/993/116028/983/9861/9656/5698/5692/5985/5713/4175/5710/7157/5984/5719/6233/7158/5884/5810/4999/4172/80010/5000/8318/51512/7532/4173/5706/9133/580/11073/891/641/5714/6119/3364/10524/5688/5687/144715/5708/1111/5704/23595/7311/5983/5694/4176/7529/1017/5684/5720/5883/10111/8317/5690/5717/9491/545/10197/7336/29086/7316/10213/4171/5715/9088/7341/5701/5685/5686/995/5716/5932/9025/79184/7156/5693/5721 129 Human_papillomavirus_type_16 R-HSA-5676590 NIK-->noncanonical NF-kB signaling 57/4644 59/10654 1.294116903784215e-18 1.2185543731605727e-17 4.315246757938181e-18 8454/5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 57 Human_papillomavirus_type_16 R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 57/4644 59/10654 1.294116903784215e-18 1.2185543731605727e-17 4.315246757938181e-18 6227/6206/1965/6234/27335/6191/8668/6224/8662/26986/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1978/1968/6230/8669/6194/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 57 Human_papillomavirus_type_16 R-HSA-1226099 Signaling by FGFR in disease 60/4644 63/10654 1.3978789468236573e-18 1.3074827749290608e-17 4.630167458952746e-18 5295/4893/11052/2250/5335/9530/613/5431/6776/5435/5433/11064/5439/2264/2885/9846/2252/2253/3845/3265/7750/8805/5290/8823/2260/5438/2249/2248/399687/2247/2246/2251/6777/1523/2963/5434/5436/9208/6774/2263/6772/2962/6654/11160/2549/5432/22916/8822/5440/5430/8817/5441/2254/4686/26281/10818/2261/5437/2255/27006 60 Human_papillomavirus_type_16 R-HSA-9604323 Negative regulation of NOTCH4 signaling 53/4644 54/10654 2.0232325586302537e-018 1.8798644236809577e-17 6.657133270641198e-18 8454/5689/5682/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/5707/7534/9861/5698/5692/5713/5710/5719/6233/5706/10460/5714/5688/5687/5708/4855/5704/7311/5694/5684/5720/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721 53 Human_papillomavirus_type_16 R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 87/4644 102/10654 2.23660174516357e-18 2.064442268726637e-17 7.310775787515271e-18 8454/8792/7124/5689/5682/356/143471/5705/10673/5709/5695/3604/7292/7133/5711/5683/5699/5702/8740/7187/51330/958/5696/5691/939/7314/5718/8945/8744/5700/122706/5707/23198/8764/9020/1896/9861/5698/5692/5713/5710/8718/9040/5719/6233/8742/4791/959/4055/8600/330/5706/5714/5688/5687/5708/5704/7311/5971/115650/5694/1147/4050/5684/5720/7186/5690/5717/9491/6500/10197/7316/10213/970/5715/7132/5701/329/23291/5685/5686/4049/5716/7293/8784/5693/5721 87 Human_papillomavirus_type_16 R-HSA-6782135 Dual incision in TC-NER 62/4644 66/10654 2.7262992350496705e-18 2.499998579591299e-17 8.853204258296832e-18 2074/5982/7507/5431/5435/9978/5433/2965/5439/2067/2967/6117/10714/7314/6118/404672/5438/5985/2068/5984/6233/7874/5424/8451/10450/5434/100534599/5436/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/2071/51426/7311/5983/5432/56655/6917/5440/902/27339/5430/57804/5441/2072/7316/5426/5437/2033/2968/56949/9716/5981/57461/1022 62 Human_papillomavirus_type_16 R-HSA-72649 Translation initiation complex formation 56/4644 58/10654 2.8888020498680853e-18 2.6148317909451117e-17 9.259861239645067e-18 6227/6206/1965/6234/27335/6191/8668/6224/8662/26986/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1968/6230/8669/6194/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 56 Human_papillomavirus_type_16 R-HSA-72702 Ribosomal scanning and start codon recognition 56/4644 58/10654 2.8888020498680853e-18 2.6148317909451117e-17 9.259861239645067e-18 6227/6206/1965/6234/27335/6191/8668/6224/8662/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1968/6230/8669/6194/1983/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 56 Human_papillomavirus_type_16 R-HSA-5610787 Hedgehog 'off' state 94/4644 113/10654 3.2378906802865536e-18 2.912026041308996e-17 1.0312310398753395e-17 8454/5689/5682/1452/51684/143471/10381/5705/5709/9978/5695/107/5711/7846/5683/5699/5702/81027/83737/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/112/5573/2737/5727/8650/111/9861/2932/5698/5692/5713/10376/5710/5719/6233/23322/196883/115/84617/54903/10382/5568/7277/5706/113/5714/5566/2736/5688/5687/347733/5708/5577/5704/7311/10383/84790/5694/7280/109/5684/5720/55081/2735/5575/6608/5690/5717/9491/6500/114/10197/108/7316/10213/2778/5715/5701/5576/5685/5686/5716/8481/5693/5721 94 Human_papillomavirus_type_16 R-HSA-1236974 ER-Phagosome pathway 74/4644 83/10654 3.286704009619458e-18 2.937099188214076e-17 1.0401101525580853e-17 8773/5689/5682/3107/811/143471/5705/10333/5709/5695/567/3106/5711/5683/929/5699/5702/3133/3551/5696/5691/7314/5718/10952/5700/122706/5707/23198/8517/6810/7096/9861/5698/5692/5713/5710/5719/6233/3135/5706/29927/5714/5688/5687/5708/2923/695/5704/7311/5694/8673/3105/23643/1147/5684/5720/5690/5717/9491/10197/7099/4615/7316/10213/5715/5701/9341/5685/5686/5716/3134/7097/5693/5721 74 Human_papillomavirus_type_16 R-HSA-166520 Signaling by NTRKs 86/4644 101/10654 4.424323493471408e-18 3.928687254012902e-17 1.391259619532648e-17 5295/627/9252/4893/5335/5291/1785/117/5605/1432/2534/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5879/5515/5607/161/5290/3667/1849/5594/5528/9261/6714/5519/5598/4208/4909/4914/6195/1213/1211/5600/1175/6300/5781/25920/4908/1173/116/6464/2904/7074/160/673/6774/26052/7867/5802/2889/6654/5900/387/2549/1020/4916/7529/5595/25759/5516/1845/4915/5604/4205/57498/10818/53358/4803/2002/1398/1385/5906/8851/5296/581 86 Human_papillomavirus_type_16 R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 104/4644 129/10654 4.6758457303199024e-18 4.12591921989863e-17 1.461105054426345e-17 8454/3725/9252/4790/7321/1785/10333/4792/1432/929/3654/6196/1759/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/1326/5601/5606/11213/8737/8767/5336/1849/29110/5594/4214/23118/841/8517/5528/7323/5970/7096/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/3665/351/3684/330/79155/8651/26052/7867/64127/5602/3656/57162/695/7189/7311/9641/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/4205/4793/3146/7322/329/23291/6288/2002/6285/5609/1385/5599/353376/7097/57161/3689/148022 104 Human_papillomavirus_type_16 R-HSA-168898 Toll-like Receptor Cascades 120/4644 155/10654 5.523788076274151e-18 4.8436716693828963e-17 1.7152815605272364e-17 8454/3725/10695/9252/4790/7321/1785/6280/10333/4792/1432/929/3654/6196/1759/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/54106/11035/8945/1326/5601/5606/11213/8737/8767/5336/1849/29110/5594/6271/4214/23118/841/8517/5528/7323/5970/7096/9261/5519/5598/4208/6195/10454/3661/6233/51311/10010/2353/8772/5600/5781/5608/4791/1508/3665/351/81793/7184/3684/8411/330/7098/338/79155/6279/8651/26052/7867/64127/5602/3656/57162/695/7189/81622/7311/9641/6416/51284/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7100/7316/4205/5289/4793/3146/7322/329/23291/6288/2002/6285/5609/1385/5599/353376/7097/57161/3689/148022 120 Human_papillomavirus_type_16 R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 93/4644 112/10654 6.2510105415707984e-18 5.447309186225981e-17 1.929046731364117e-17 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/6208/6170/6203/10952/6147/6222/6727/6184/58477/6134/6747/6731/6155/6729/6231/6142/23521/6207/6233/6188/6122/6230/6194/6166/1650/6136/6125/6232/6160/6748/29927/6193/6210/6229/6205/140801/6235/6181/23471/7311/6223/25873/6730/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/6209/11224/6130/6204/6228/6124/6189/9789/6135/6201/6161/6133 93 Human_papillomavirus_type_16 R-HSA-4641258 Degradation of DVL 55/4644 57/10654 6.44395978554285e-18 5.5465494350408706e-17 1.9641905190676302e-17 5689/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/1855/5696/5691/7314/5718/5700/122706/5707/1856/23198/9861/5698/5692/5713/5710/5719/6233/1857/5706/5714/5688/5687/5708/51339/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/23072/5693/5721 55 Human_papillomavirus_type_16 R-HSA-69541 Stabilization of p53 55/4644 57/10654 6.44395978554285e-18 5.5465494350408706e-17 1.9641905190676302e-17 5689/5682/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/51230/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721/4193 55 Human_papillomavirus_type_16 R-HSA-5688426 Deubiquitination 202/4644 297/10654 6.562888253539941e-18 5.614470865680815e-17 1.9882434246924597e-17 5689/221937/645836/5682/79594/7419/10474/7321/4738/7375/9817/10445/91833/3091/143471/100287513/5705/8239/5709/5695/4792/9986/11047/4609/392188/4194/4089/100287144/5711/7347/4088/5683/324/408/64135/5699/8312/100287327/5702/8900/57599/377630/672/6881/51616/7187/7040/728386/7345/3054/1540/100287404/5696/5691/7314/5718/3607/90865/2648/5700/122706/5707/8027/8737/83444/8767/171023/55611/100287364/51720/57646/23198/63967/9101/8517/86/993/890/7417/80124/983/4092/2099/1643/9861/23586/64426/100287441/8850/7128/7046/6502/5698/9146/5692/5713/5710/10454/8473/7157/10869/9958/5719/6233/100287478/9804/55593/84282/93973/10318/23770/8607/7874/100287178/5886/100287238/10600/23326/8237/4303/409/330/5706/4287/27005/7706/580/7416/79155/25862/9738/8658/84132/5714/79589/55288/64127/5688/9097/5687/5708/4087/63891/7189/5704/7048/7311/367/114548/387/60/5694/7528/9960/23358/5684/8295/5720/10617/7186/56957/6885/991/51377/10392/5690/2625/57506/5717/9491/4086/1080/57695/10197/64750/29086/7316/10213/8314/8678/9100/7415/5715/5701/4798/329/9099/5685/5686/2033/5728/5716/79184/78990/5887/9736/5693/154/10254/5721/100287205/4193 202 Human_papillomavirus_type_16 R-HSA-1169408 ISG15 antiviral mechanism 66/4644 72/10654 6.809411765208176e-18 5.79006345853762e-17 2.050425743654392e-17 3839/23165/5335/348995/57122/23511/4734/23279/8672/23225/1973/3836/4599/9972/8021/7334/55746/7314/402569/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/1977/51191/6233/5610/6396/129401/4928/3838/5903/55706/7175/4600/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/1974/5595/3837/81929/9631/79023/23636/7316/53371/9688/5300/9775/5495/8480 66 Human_papillomavirus_type_16 R-HSA-73762 RNA Polymerase I Transcription Initiation 47/4644 47/10654 9.852254914499203e-18 8.326935930748422e-17 2.9488042610295654e-17 2074/9112/5435/5928/2965/64425/1107/2967/2648/30834/404672/8850/57459/2068/3066/9533/5434/9015/79101/9219/5931/221830/7270/4331/9013/1108/2966/54815/2071/10849/57504/6908/53615/5440/902/9014/25885/54700/5441/51082/7343/5437/3065/2968/84172/1022/10919 47 Human_papillomavirus_type_16 R-HSA-180534 Vpu mediated degradation of CD4 51/4644 52/10654 1.0387890708518208e-17 8.522930212895349e-17 3.0182113969963645e-17 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/920/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_papillomavirus_type_16 R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 51/4644 52/10654 1.0387890708518208e-17 8.522930212895349e-17 3.0182113969963645e-17 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_papillomavirus_type_16 R-HSA-69610 p53-Independent DNA Damage Response 51/4644 52/10654 1.0387890708518208e-17 8.522930212895349e-17 3.0182113969963645e-17 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_papillomavirus_type_16 R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 51/4644 52/10654 1.0387890708518208e-17 8.522930212895349e-17 3.0182113969963645e-17 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_papillomavirus_type_16 R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 51/4644 52/10654 1.0387890708518208e-17 8.522930212895349e-17 3.0182113969963645e-17 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/2932/5698/5692/5713/595/5710/5719/6233/1019/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_papillomavirus_type_16 R-HSA-438064 Post NMDA receptor activation events 72/4644 81/10654 1.3990891637295995e-17 1.1412337771585046e-16 4.0414325904551465e-17 5563/4893/51807/817/53632/10381/107/7846/81027/1741/1739/6196/1740/8874/6197/3845/3265/814/5879/5923/818/57554/79861/5567/5594/51422/5573/2902/6714/10376/6195/5613/801/2891/805/5170/84617/3838/2904/2890/10382/5568/7277/10645/5566/84254/5571/27330/347733/3084/816/5577/5562/10383/84790/5564/5565/7280/5595/815/28964/5575/114/5576/2903/4137/2066/1742/88/1385/808/8536 72 Human_papillomavirus_type_16 R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 74/4644 84/10654 1.5847361263604176e-17 1.2851935175050092e-16 4.551234874609779e-17 10445/5982/6613/7507/9978/85015/10980/2965/10987/2067/2967/6612/6117/7334/10714/7314/6118/83444/404672/9557/86/3978/1643/5985/2068/5984/6233/93973/8607/5424/5886/8451/8554/7515/54107/8450/4331/5425/5111/2966/6119/5427/1642/142/2071/1069/7329/51426/2873/7311/3980/60/8533/5983/10038/51138/7528/56655/9318/902/57804/7336/2072/54778/7316/5426/7341/4798/2968/5887/5981/1022/50813/7508 74 Human_papillomavirus_type_16 R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 80/4644 93/10654 1.8204832170116206e-17 1.4430157929193806e-16 5.110128328453672e-17 8454/3725/9252/4790/4792/1432/929/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/3665/351/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/4205/4793/3146/23291/6288/2002/6285/5609/1385/5599/353376/57161/148022 80 Human_papillomavirus_type_16 R-HSA-2408557 Selenocysteine synthesis 80/4644 93/10654 1.8204832170116206e-17 1.4430157929193806e-16 5.110128328453672e-17 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/6209/11224/6130/6204/6228/6124/6189/6135/6201/6161/6133 80 Human_papillomavirus_type_16 R-HSA-442755 Activation of NMDA receptors and postsynaptic events 80/4644 93/10654 1.8204832170116206e-17 1.4430157929193806e-16 5.110128328453672e-17 5563/4893/51807/817/53632/10381/107/7846/81027/1741/1739/6196/1740/8874/6197/8825/3845/3265/814/5879/5923/818/57554/79861/5567/5594/51422/2892/5573/2902/6714/10376/6195/5613/801/2891/805/5170/84617/320/3838/8573/2904/2890/10382/5568/7277/10645/55327/5566/84254/5571/27330/347733/3084/816/5577/2893/5562/10383/84790/5564/5565/7280/5595/64130/815/28964/5575/114/5576/2903/4137/2066/9647/1742/88/1385/808/8536 80 Human_papillomavirus_type_16 R-HSA-975155 MyD88 dependent cascade initiated on endosome 80/4644 93/10654 1.8204832170116206e-17 1.4430157929193806e-16 5.110128328453672e-17 8454/3725/9252/4790/4792/1432/929/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/3665/351/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/4205/4793/3146/23291/6288/2002/6285/5609/1385/5599/353376/57161/148022 80 Human_papillomavirus_type_16 R-HSA-187037 Signaling by NTRK1 (TRKA) 71/4644 80/10654 2.879709032826445e-17 2.2697931309300574e-16 8.03798145176867e-17 5295/9252/4893/5335/5291/1785/117/5605/1432/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5515/5607/161/5290/3667/1849/5594/5528/9261/6714/5519/5598/4208/4914/6195/1213/1211/5600/1175/6300/1173/116/6464/160/673/6774/26052/7867/2889/6654/5900/387/7529/5595/25759/5516/1845/4915/5604/4205/57498/10818/53358/4803/2002/1398/1385/5906/5296 71 Human_papillomavirus_type_16 R-HSA-4086400 PCP/CE pathway 79/4644 92/10654 3.629497787245539e-17 2.8289918863919395e-16 1.0018262898128039e-16 5689/5579/5682/5578/1212/5582/143471/5705/5709/5695/5881/5711/5683/5699/5702/1855/163/5696/5691/4920/7314/5879/5718/161/5700/122706/5707/1856/8322/23198/7471/9861/5698/5880/5692/5713/23002/5710/5719/6233/7474/1857/1213/1211/1175/1173/144165/409/5706/160/5714/5688/5687/5708/5704/7311/387/5694/57154/5684/5720/5690/5717/9491/50855/10197/64750/7316/10213/5216/5715/5701/5685/5686/23513/5716/5693/5721/6259 79 Human_papillomavirus_type_16 R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 79/4644 92/10654 3.629497787245539e-17 2.8289918863919395e-16 1.0018262898128039e-16 8454/3725/9252/4790/4792/1432/929/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/351/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/4205/4793/3146/23291/6288/2002/6285/5609/1385/5599/353376/57161/148022 79 Human_papillomavirus_type_16 R-HSA-8939902 Regulation of RUNX2 expression and activity 66/4644 73/10654 4.078160708353717e-17 3.1611378308399253e-16 1.1194485922320178e-16 8454/5689/7291/5682/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/865/11059/2099/9861/2932/6502/5698/5692/5713/5710/5719/6233/5706/579/5714/6772/5688/5687/2908/5708/5704/7311/860/1750/5694/57154/5684/5720/10273/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721/10891 66 Human_papillomavirus_type_16 R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 61/4644 66/10654 4.4911266118454115e-17 3.4621157342962157e-16 1.2260334070509164e-16 5689/5682/64344/7321/3091/143471/5705/5709/9978/5695/5711/5683/5699/7428/5702/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/112399/84962/5706/5714/5688/5687/5708/5704/7311/2034/5694/5684/5720/5690/5717/9491/10197/7316/10213/7322/5715/5701/112398/5685/5686/8453/5716/54583/5693/5721 61 Human_papillomavirus_type_16 R-HSA-1227986 Signaling by ERBB2 49/4644 50/10654 5.3231706592033466e-17 4.058917627642552e-16 1.4373778896704692e-16 5295/4893/5335/26469/5578/2064/5753/145957/2534/4145/9542/2885/3845/3265/7314/1839/5290/2065/2069/9101/6714/10000/6233/7525/5580/1729/6464/5782/10193/3084/2886/208/6654/10718/7311/387/1956/2549/11140/8065/685/10273/207/7316/1950/51072/3320/2066/5581 49 Human_papillomavirus_type_16 R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 49/4644 50/10654 5.3231706592033466e-17 4.058917627642552e-16 1.4373778896704692e-16 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 49 Human_papillomavirus_type_16 R-HSA-3371453 Regulation of HSF1-mediated heat shock response 63/4644 69/10654 6.469696962114882e-17 4.880099375186656e-16 1.7281816446622664e-16 23165/6782/573/7531/9530/348995/472/57122/3313/23511/3305/23279/259217/23225/3309/9531/3306/9972/23411/8021/6117/3312/55746/51182/3303/6118/5594/3308/10049/3337/10762/9261/79902/9883/2932/6396/129401/3297/4928/5903/55706/7175/4927/6119/57805/3310/7266/8086/3304/5595/81929/9631/545/79023/23636/10808/53371/9532/9688/6767/22824/9529/8480 63 Human_papillomavirus_type_16 R-HSA-8948751 Regulation of PTEN stability and activity 63/4644 69/10654 6.469696962114882e-17 4.880099375186656e-16 1.7281816446622664e-16 5689/5682/1459/1460/143471/5705/5709/5695/1457/4734/11060/5711/5683/5699/2444/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/10000/5692/5713/5710/5719/6233/331/23608/5706/8658/5714/5688/5687/5708/208/5704/7311/5694/5684/5720/10273/207/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5728/5987/5716/5693/5721 63 Human_papillomavirus_type_16 R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 82/4644 97/10654 6.651855923839944e-17 4.990670513982589e-16 1.7673380219828054e-16 8454/3725/9252/4790/4792/1432/929/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/3665/351/8411/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/4205/5289/4793/3146/23291/6288/2002/6285/5609/1385/5599/353376/57161/148022 82 Human_papillomavirus_type_16 R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 52/4644 54/10654 7.120496706186548e-17 5.31386004190411e-16 1.881788603202716e-16 8454/5689/5682/143471/5705/5709/9978/5695/6790/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 52 Human_papillomavirus_type_16 R-HSA-177929 Signaling by EGFR 48/4644 49/10654 1.2040985592333602e-16 8.837414367965655e-16 3.1295791587048724e-16 5295/374/4893/5335/7039/55824/6456/6868/30011/2885/8874/3845/3265/10252/5829/7314/1839/5290/8027/2060/2069/102/6714/9146/6455/1445/6233/29924/255324/5781/6464/5782/5796/998/6654/7311/1956/2549/10253/685/26018/58513/7316/1950/867/5774/10254/6457 48 Human_papillomavirus_type_16 R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 48/4644 49/10654 1.2040985592333602e-16 8.837414367965655e-16 3.1295791587048724e-16 9134/57060/2810/1869/6790/25904/1647/8900/55571/55835/57472/144455/85456/29883/1263/7027/7832/898/5934/890/10769/983/7157/7029/5325/79733/1820/4869/4850/891/5111/246175/4848/23019/1874/1017/25946/4849/1027/9337/1026/5933/28984/2033/995/10498/581/3276 48 Human_papillomavirus_type_16 R-HSA-69231 Cyclin D associated events in G1 44/4644 44/10654 1.209396691838493e-16 8.837414367965655e-16 3.1295791587048724e-16 8454/5925/1869/5753/1031/3717/5520/1032/28227/1030/5518/7314/5515/25/7027/5934/6714/5519/6502/595/896/6233/7029/1163/1019/1029/4331/4067/1874/1870/7311/5516/894/902/1027/6500/7316/1875/1026/5933/1871/1021/1022/1028 44 Human_papillomavirus_type_16 R-HSA-69236 G1 Phase 44/4644 44/10654 1.209396691838493e-16 8.837414367965655e-16 3.1295791587048724e-16 8454/5925/1869/5753/1031/3717/5520/1032/28227/1030/5518/7314/5515/25/7027/5934/6714/5519/6502/595/896/6233/7029/1163/1019/1029/4331/4067/1874/1870/7311/5516/894/902/1027/6500/7316/1875/1026/5933/1871/1021/1022/1028 44 Human_papillomavirus_type_16 R-HSA-450294 MAP kinase activation 59/4644 64/10654 2.048710576522474e-16 1.4892958232440575e-15 5.274019046188207e-16 8454/3725/9252/4790/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/23118/8517/5528/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/79155/7867/64127/5602/3656/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/7316/4205/23291/2002/5609/1385/5599 59 Human_papillomavirus_type_16 R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 68/4644 77/10654 2.485980021275365e-16 1.7978504999223387e-15 6.366698698003107e-16 1912/23165/7486/6045/80012/10274/348995/6613/57122/23511/1911/6672/23279/23225/165918/57332/5371/8924/672/9972/6612/8021/6117/55746/51564/51588/7518/10762/79902/9656/9883/84733/9063/6396/129401/7703/6015/8554/4928/5903/55706/7175/1029/8535/5885/641/493861/4927/8243/142/1069/8086/7329/648/81929/5893/9631/79023/23636/10735/53371/6996/23137/9688/7341/9126/8480/7508 68 Human_papillomavirus_type_16 R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 80/4644 95/10654 2.549761947050159e-16 1.8251612304649862e-15 6.46341374332801e-16 8454/3725/9252/4790/10333/4792/1432/929/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/11213/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/4205/4793/3146/23291/6288/2002/6285/5609/1385/5599/7097/57161 80 Human_papillomavirus_type_16 R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 80/4644 95/10654 2.549761947050159e-16 1.8251612304649862e-15 6.46341374332801e-16 8454/3725/9252/4790/10333/4792/1432/929/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/11213/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/4205/4793/3146/23291/6288/2002/6285/5609/1385/5599/7097/57161 80 Human_papillomavirus_type_16 R-HSA-194315 Signaling by Rho GTPases 283/4644 455/10654 2.7599272670666495e-16 1.9655725663423904e-15 6.960650120520751e-16 55839/11130/7984/394/64837/71/6249/51517/5579/392/9735/7531/55789/5526/29/51807/2909/10971/5578/9212/613/1894/388/7533/2810/147841/147179/348995/54509/10381/57122/10276/6280/1780/23122/3688/5048/57405/8655/10094/23279/5881/1432/2017/2491/9138/7846/23365/23081/79784/9475/1060/171177/9322/397/81027/4628/11004/8976/1855/2885/23433/6093/9184/8997/8826/10499/5518/8874/23332/25909/3071/10726/81930/5062/55746/9411/5879/5515/9181/26999/25/79682/1072/10403/79861/4638/25936/4659/10093/1856/10006/4771/389/5594/29127/3619/64105/89839/1124/7534/332/5528/6453/9828/6714/79902/3796/5519/81565/57636/999/89953/396/10810/5880/85360/91687/11243/10376/23002/57584/58504/83540/7410/5580/7409/1857/128239/9055/4649/23191/7514/54820/29984/1729/6396/1535/5600/91614/801/64946/9793/10109/5586/140735/9886/2664/5500/10787/4221/805/220134/5170/84617/4928/9743/5590/114793/5903/55055/5747/80776/1783/401541/7204/2316/7532/3633/27237/10382/7074/10627/79172/7277/10451/79980/58480/6232/5501/10152/6279/55288/54821/10092/9183/10163/1062/699/347733/22919/55845/5063/3895/5529/51143/998/695/10788/6654/10097/57120/367/57381/10383/5347/387/6655/60/84790/84643/5058/93663/7280/7529/5595/64130/1778/5516/5905/81929/3984/54908/55143/1495/1499/5525/4690/1058/991/79019/4627/10928/348235/80152/10458/1063/3985/8379/1027/1080/23421/55920/79023/6242/1781/9824/10398/4085/5289/5585/5216/4168/10552/81624/55166/8936/4637/995/79003/391/23221/23028/89941/2/1742/90627/5527/10096/7454/701/23380/9928/3799/103910/57551/5296/5300/808/10095/399/4952/10672 283 Human_papillomavirus_type_16 R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 53/4644 56/10654 3.4344729223333547e-16 2.433618944461463e-15 8.61813513738088e-16 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/9861/5698/5692/5713/5710/5719/6233/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 53 Human_papillomavirus_type_16 R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/4644 52/10654 3.5185001258476496e-16 2.480630993248368e-15 8.784618140175037e-16 5689/5682/143471/472/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Human_papillomavirus_type_16 R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 73/4644 85/10654 5.764460455607247e-16 4.003731692681668e-15 1.4178349843911523e-15 8454/3725/9252/4790/4792/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/81793/79155/7867/64127/5602/3656/57162/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/4615/7100/7316/4205/4793/3146/23291/6288/2002/6285/5609/1385/5599/57161 73 Human_papillomavirus_type_16 R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 73/4644 85/10654 5.764460455607247e-16 4.003731692681668e-15 1.4178349843911523e-15 8454/3725/9252/4790/4792/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/81793/79155/7867/64127/5602/3656/57162/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/4615/7100/7316/4205/4793/3146/23291/6288/2002/6285/5609/1385/5599/57161 73 Human_papillomavirus_type_16 R-HSA-975871 MyD88 cascade initiated on plasma membrane 73/4644 85/10654 5.764460455607247e-16 4.003731692681668e-15 1.4178349843911523e-15 8454/3725/9252/4790/4792/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/81793/79155/7867/64127/5602/3656/57162/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/4615/7100/7316/4205/4793/3146/23291/6288/2002/6285/5609/1385/5599/57161 73 Human_papillomavirus_type_16 R-HSA-167161 HIV Transcription Initiation 46/4644 47/10654 6.151081152230194e-16 4.149022527201424e-15 1.4692865910185483e-15 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/5437/2968/138474/1022 46 Human_papillomavirus_type_16 R-HSA-167162 RNA Polymerase II HIV Promoter Escape 46/4644 47/10654 6.151081152230194e-16 4.149022527201424e-15 1.4692865910185483e-15 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/5437/2968/138474/1022 46 Human_papillomavirus_type_16 R-HSA-73776 RNA Polymerase II Promoter Escape 46/4644 47/10654 6.151081152230194e-16 4.149022527201424e-15 1.4692865910185483e-15 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/5437/2968/138474/1022 46 Human_papillomavirus_type_16 R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 46/4644 47/10654 6.151081152230194e-16 4.149022527201424e-15 1.4692865910185483e-15 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/5437/2968/138474/1022 46 Human_papillomavirus_type_16 R-HSA-75953 RNA Polymerase II Transcription Initiation 46/4644 47/10654 6.151081152230194e-16 4.149022527201424e-15 1.4692865910185483e-15 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/5437/2968/138474/1022 46 Human_papillomavirus_type_16 R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 46/4644 47/10654 6.151081152230194e-16 4.149022527201424e-15 1.4692865910185483e-15 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/5437/2968/138474/1022 46 Human_papillomavirus_type_16 R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 49/4644 51/10654 7.811428116624652e-16 5.2437481567580795e-15 1.856959995490726e-15 6227/6206/1965/6234/27335/6191/8668/6224/8662/6202/6218/3921/8665/6208/6203/8666/6222/8667/6231/8663/8894/6207/6233/51386/6188/1968/6230/8669/6194/6232/6193/6210/6229/6205/6235/6223/8664/6187/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 49 Human_papillomavirus_type_16 R-HSA-5693532 DNA Double-Strand Break Repair 123/4644 166/10654 9.111679301668533e-16 6.087469552495691e-15 2.1557456793922544e-15 2237/83990/151987/5892/9156/1763/7486/27343/5982/11200/472/6613/80198/3981/2140/64421/4683/165918/84126/8900/8924/2067/672/6117/7334/10714/348654/83695/55183/7314/6118/25/5888/322/51588/7518/51720/63967/5531/116028/2070/890/197342/9031/7517/9656/84464/5985/7157/5984/6233/7158/6047/5884/5810/5424/8467/80010/3838/7516/7515/54107/580/11073/5591/5425/641/5111/6119/3364/22976/10524/5427/144715/5889/55775/5429/142/1111/9682/7329/79728/51426/146956/7311/23030/3980/5536/5983/10038/2547/79840/56655/51750/1017/54962/5893/5883/10111/57804/7520/675/51548/545/7336/2072/29086/7316/8314/5426/10635/7341/8914/23514/5932/2138/9025/79184/7156/5890/5599/5981/2139 123 Human_papillomavirus_type_16 R-HSA-8848021 Signaling by PTK6 51/4644 54/10654 1.6397861969452111e-15 1.0851981293934582e-14 3.8429944635458774e-15 4893/1796/5770/2909/9021/27043/3091/2064/5753/145957/9542/9564/3845/3265/5829/7314/5879/120892/1839/2065/2069/898/202559/5921/6421/595/6233/1019/10657/1793/6774/2908/3084/10718/7311/2034/387/1956/63916/1017/685/207/55620/1027/10457/7316/1950/867/2066/1398/9844 51 Human_papillomavirus_type_16 R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 51/4644 54/10654 1.6397861969452111e-15 1.0851981293934582e-14 3.8429944635458774e-15 4893/1796/5770/2909/9021/27043/3091/2064/5753/145957/9542/9564/3845/3265/5829/7314/5879/120892/1839/2065/2069/898/202559/5921/6421/595/6233/1019/10657/1793/6774/2908/3084/10718/7311/2034/387/1956/63916/1017/685/207/55620/1027/10457/7316/1950/867/2066/1398/9844 51 Human_papillomavirus_type_16 R-HSA-5678895 Defective CFTR causes cystic fibrosis 56/4644 61/10654 1.9751398882674922e-15 1.3009958982344093e-14 4.607195588150514e-15 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/5696/5691/7314/5718/5700/122706/5707/10956/79139/91445/23198/9861/5698/5692/5713/5710/5719/6233/6048/5706/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 56 Human_papillomavirus_type_16 R-HSA-169911 Regulation of Apoptosis 50/4644 53/10654 3.576877410296671e-15 2.3450275731991725e-14 8.304407957009487e-15 5689/5682/4976/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Human_papillomavirus_type_16 R-HSA-170834 Signaling by TGF-beta Receptor Complex 64/4644 73/10654 4.293591800621038e-15 2.7888468964219055e-14 9.876098098894397e-15 892/7321/4738/8239/9612/4609/4089/22938/23327/4088/5499/1030/7040/904/7314/5054/7027/6497/51592/50848/7323/6667/4092/11171/7050/7046/5494/9958/9040/6233/7514/1025/7029/57530/5500/4221/5590/3726/5501/1024/60436/8812/1874/142/905/4087/7048/7311/387/57154/51377/10273/50855/64750/54778/7316/1875/9611/5933/867/3065/6498/56288/25937 64 Human_papillomavirus_type_16 R-HSA-5654738 Signaling by FGFR2 64/4644 73/10654 4.293591800621038e-15 2.7888468964219055e-14 9.876098098894397e-15 5295/4893/2250/5335/54845/5431/5435/5433/5439/2885/7073/5518/2252/2253/3845/3265/7314/5515/5290/8823/5594/5438/3185/2249/6714/2248/4670/2247/6233/2246/2251/5781/5725/2963/5434/6464/5436/673/2263/2962/6654/7311/2549/5432/22916/5595/5516/8822/10253/5440/5430/3178/8817/5441/2254/4686/7316/26281/10818/867/5437/2255/27006/3187 64 Human_papillomavirus_type_16 R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 43/4644 44/10654 7.071882098868099e-15 4.572281375443291e-14 1.6191745576840858e-14 892/7321/8239/9612/4609/4089/22938/23327/4088/1030/904/7314/5054/7027/6497/51592/7323/6667/4092/7050/5494/6233/1025/7029/4221/3726/1024/60436/8812/1874/142/905/4087/7311/64750/54778/7316/1875/9611/5933/3065/6498/25937 43 Human_papillomavirus_type_16 R-HSA-674695 RNA Polymerase II Pre-transcription Events 71/4644 84/10654 8.447138318912851e-15 5.436392230015931e-14 1.9251807274393366e-14 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/11198/904/51497/4300/80349/2959/404672/5438/83860/2068/1025/23168/6883/7936/6829/2957/123169/25920/2963/5434/5436/6878/79577/4331/8148/2966/2962/4298/54457/8812/905/2071/6880/6908/6882/2961/5432/22916/55840/6877/6917/5440/902/6830/5430/6749/5441/7469/4686/6872/6879/9150/5437/6827/2968/138474/1022/8178 71 Human_papillomavirus_type_16 R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 80/4644 98/10654 8.986372418694754e-15 5.730854774285791e-14 2.029458268719581e-14 8454/3725/9252/4790/10333/4792/1432/929/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/11213/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/4205/4793/3146/23291/6288/2002/6285/5609/1385/5599/7097/57161 80 Human_papillomavirus_type_16 R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 80/4644 98/10654 8.986372418694754e-15 5.730854774285791e-14 2.029458268719581e-14 8454/3725/9252/4790/10333/4792/1432/929/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/11213/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/4205/4793/3146/23291/6288/2002/6285/5609/1385/5599/7097/57161 80 Human_papillomavirus_type_16 R-HSA-2682334 EPH-Ephrin signaling 76/4644 92/10654 1.2066173949821565e-14 7.660109525610703e-14 2.7126621120818194e-14 71/2042/1212/23385/2051/10094/79784/2047/2534/9475/4628/8976/6093/163/8997/1759/8440/8874/3265/5062/5879/1072/161/10093/5921/6453/4313/2902/2041/102/6714/1943/2043/7525/1942/7410/1213/1211/1175/10109/5663/1173/2904/5747/7074/1949/10627/1945/10451/4318/160/8218/10092/4067/5063/6386/998/2048/10097/387/60/5058/3984/28964/4627/3985/6383/10398/10552/4637/1946/10096/103910/1944/10095/1969 76 Human_papillomavirus_type_16 R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission 144/4644 206/10654 1.2156082869068304e-14 7.682425344731005e-14 2.7205647767663537e-14 2788/5563/4893/5579/5331/23426/2900/2770/51807/817/2550/5578/2898/5582/53632/10381/9463/107/9568/7846/9495/2782/81027/1134/1741/1739/163/6196/1740/10368/8874/2897/6197/8825/3845/3265/814/2773/5879/2787/5923/818/57554/161/79861/5567/4646/5594/51422/10681/112/2892/5573/2902/111/2901/2792/3359/6714/2567/2785/10376/6195/2783/2784/83988/5613/2771/196883/3759/115/1175/801/2891/2791/805/5170/1173/84617/320/3838/59283/8573/2904/2890/10382/2556/5568/2036/7277/160/113/10645/2899/55327/5566/84254/5571/27330/347733/3084/816/3763/2786/5577/10369/2893/5562/10383/84790/5564/5565/7280/109/5595/64130/815/54331/28964/3761/5575/59345/51764/94235/114/108/55970/346562/2793/5576/2903/4137/2066/4905/27092/9647/1742/88/1385/3768/808/8536/4193/2790 144 Human_papillomavirus_type_16 R-HSA-5358351 Signaling by Hedgehog 111/4644 149/10654 1.2347766321514077e-14 7.768572264163342e-14 2.7510718450576565e-14 8454/5689/5682/22873/1452/51684/143471/10381/5705/8452/5709/9978/5695/107/5711/7846/5683/408/5699/6400/5702/81027/83737/6868/6469/5696/5691/7314/5718/8945/5700/122706/5707/5567/10956/23198/112/5573/2737/5727/8650/111/9861/8405/2932/5698/5692/5713/10376/5710/5719/6233/23322/196883/115/84617/54903/10382/5568/409/79577/7277/5706/113/84447/5714/5566/2736/5688/5687/347733/5708/5577/5704/7311/10383/84790/5694/7280/109/57154/5684/5720/55081/2735/5575/6608/5690/5717/9491/6500/114/10197/108/64750/132884/7316/10213/2778/7415/5715/5701/5576/5685/5686/5716/8481/5693/2622/5721/5034 111 Human_papillomavirus_type_16 R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 51/4644 55/10654 1.2973414495137827e-14 8.089644682968165e-14 2.86477269787371e-14 51807/10381/1780/3305/8655/84516/832/7846/81027/3306/3312/51164/3303/79861/3337/10376/3301/10540/140735/84617/5241/11258/1783/10382/93661/10294/55860/830/7277/10671/1639/2908/347733/51143/3326/367/10383/84790/3304/7280/10728/829/1778/4306/1781/2289/10121/3320/10963/55466/2288 51 Human_papillomavirus_type_16 R-HSA-4641257 Degradation of AXIN 51/4644 55/10654 1.2973414495137827e-14 8.089644682968165e-14 2.86477269787371e-14 5689/5682/143471/5705/5709/5695/5711/5683/5699/8312/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/8658/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_papillomavirus_type_16 R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 58/4644 65/10654 1.429188762493013e-14 8.87235324680397e-14 3.141952006971133e-14 3725/4436/5892/472/5431/5435/5433/2965/5439/672/2967/1386/11198/904/51497/2176/404672/5438/1643/9656/2177/2068/7157/1025/2353/7936/6829/25920/2963/5434/5436/4292/4331/2966/2962/8812/905/1111/2071/55215/5432/6917/5440/8621/902/5430/6749/545/5441/7469/5395/9150/5437/51755/6827/2968/1022/8178 58 Human_papillomavirus_type_16 R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 72/4644 86/10654 1.5186072794836145e-14 9.385929573196085e-14 3.323823955095136e-14 5295/5335/71/51517/5291/2268/147179/10094/2534/8976/2885/3071/5879/26999/25/1072/5290/10093/10006/5336/4771/5594/4644/8398/4641/6714/10810/7525/7410/5580/7409/23191/10109/10787/5747/2209/10451/1793/6850/10152/10092/10163/4067/55845/998/695/3326/10097/60/5058/63916/5595/3984/23646/4690/4627/10458/919/3055/10552/10768/8936/917/3320/1398/10096/7454/9844/5296/5581/5338/10095 72 Human_papillomavirus_type_16 R-HSA-5655253 Signaling by FGFR2 in disease 42/4644 43/10654 1.5941707281490425e-14 9.766906251498282e-14 3.4587386057749854e-14 5295/4893/2250/5335/5431/5435/5433/5439/2885/2252/2253/3845/3265/5290/8823/5438/2249/2248/2247/2246/2251/2963/5434/5436/2263/2962/6654/2549/5432/22916/8822/5440/5430/8817/5441/2254/4686/26281/10818/5437/2255/27006 42 Human_papillomavirus_type_16 R-HSA-75893 TNF signaling 42/4644 43/10654 1.5941707281490425e-14 9.766906251498282e-14 3.4587386057749854e-14 7124/25999/7375/9530/8439/10616/6868/1540/3551/7314/257397/90268/81858/8737/55072/23118/841/8517/8887/7128/10454/6233/6610/8772/331/8717/84888/56928/330/27005/8567/7311/1147/7186/56957/6885/7316/7132/329/9099/55512/7185 42 Human_papillomavirus_type_16 R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 45/4644 47/10654 1.88039745395892e-14 1.1420768951966946e-13 4.0444183106339043e-014 8454/79718/892/3091/9978/9759/9612/4609/22938/1387/6907/9794/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/7091/8850/3066/6233/7089/7090/10046/1024/10014/7088/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 45 Human_papillomavirus_type_16 R-HSA-6783783 Interleukin-10 signaling 45/4644 47/10654 1.88039745395892e-14 1.1420768951966946e-13 4.0444183106339043e-014 729230/7124/1437/3593/5743/941/3383/6349/3576/2920/1435/7133/3606/6347/3588/3569/3592/3587/6367/3976/3627/7076/7850/7297/3557/6351/6774/1440/3552/3716/1234/3586/3554/2208/3553/1230/2919/2357/6352/6348/6364/7132/942/6363/5724 45 Human_papillomavirus_type_16 R-HSA-180585 Vif-mediated degradation of APOBEC3G 50/4644 54/10654 2.779051757719001e-14 1.680607593137827e-13 5.95150830146719e-14 5689/5682/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/8065/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Human_papillomavirus_type_16 R-HSA-388841 Costimulation by the CD28 family 61/4644 70/10654 3.563858852166537e-14 2.1459630770771035e-13 7.599464098588685e-14 5295/5777/5526/941/3115/3113/3117/2534/2885/2475/5518/3127/5062/5879/5515/1326/5290/8764/57761/3126/5528/9020/6714/5519/29126/10000/1445/916/7525/7409/3932/5781/1493/940/3120/5170/3123/80380/3122/920/8503/4067/29851/5063/5529/998/208/79109/3125/5058/5516/9402/5525/3119/207/919/915/917/942/5527/5296 61 Human_papillomavirus_type_16 R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 41/4644 42/10654 3.591323257863151e-14 2.1532592011888894e-13 7.625301744090902e-14 83990/5892/9156/1763/7486/5982/472/4683/84126/672/6117/83695/6118/5888/116028/7517/5985/5984/5884/5810/80010/7516/580/11073/641/6119/3364/10524/144715/5889/1111/79728/5983/5883/10111/675/545/10635/5932/7156/5890 41 Human_papillomavirus_type_16 R-HSA-167172 Transcription of the HIV genome 63/4644 73/10654 3.654129994073919e-14 2.181593353908812e-13 7.725641017706114e-14 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/11198/904/51497/2959/404672/5438/83860/2068/1025/6883/7936/6829/2957/25920/2963/5434/5436/6878/4331/8148/2966/2962/54457/8812/905/2071/6880/6908/6882/2961/5432/22916/6877/6917/5440/902/5430/6749/5441/7469/4686/6872/6879/9150/5437/6827/2968/138474/1022/8178 63 Human_papillomavirus_type_16 R-HSA-176187 Activation of ATR in response to replication stress 37/4644 37/10654 4.185770255582156e-14 2.4884049443143073e-13 8.81214790648875e-14 5982/4174/84515/4998/10926/990/84126/55388/6117/5001/6118/23594/63967/993/5985/4175/5984/5884/5810/4999/4172/5000/8318/4173/6119/3364/144715/1111/23595/5983/4176/1017/5883/8317/545/4171/995 37 Human_papillomavirus_type_16 R-HSA-375276 Peptide ligand-binding receptors 140/4644 201/10654 4.5113298365024844e-14 2.670631122621513e-13 9.457462504237943e-14 729230/2532/4160/10316/2149/7852/1237/4987/51289/3060/6349/3576/6360/4985/2920/2921/1236/554/2831/5367/4988/6370/58191/6755/1524/643/4161/185/339403/2847/2833/6347/187/6750/2587/6387/10663/4889/9283/727/122042/1909/117579/3579/2358/5179/27202/6367/8811/56923/2832/2826/6376/5443/6354/3627/6346/9034/59350/51554/51083/2829/1233/6366/2861/728/183/10022/6373/6357/4159/2151/6869/6361/50865/10803/351/8484/6351/4158/6863/6752/84539/6753/3577/594857/4157/5368/6754/8862/301/6751/5020/186/10563/5540/256933/10850/624/4852/5473/4283/1910/10874/6356/56477/387129/129521/1234/57007/283869/4986/6374/5539/2852/1230/4886/2919/5196/3827/5173/2357/6352/6348/1906/6364/5697/3640/6288/6372/719/6363/2359/5660/1325/1232/551/4887/718/623 140 Human_papillomavirus_type_16 R-HSA-72202 Transport of Mature Transcript to Cytoplasm 70/4644 84/10654 5.69889359227889e-14 3.359473827717346e-13 1.1896849958229264e-13 23165/8683/6431/199746/348995/57122/23511/81608/65109/23279/23225/9877/9972/8021/55746/53981/7919/6432/6430/56001/10762/22794/9785/11338/4116/79902/9883/10250/51362/1977/6396/129401/2733/84324/4928/5903/55706/7175/7884/6428/10212/55110/6429/4927/10898/10569/9295/10482/51692/8086/9939/6426/22916/10921/81929/9631/29894/79023/23636/4686/8189/53371/7307/9688/9984/10189/9775/6427/8480/55339 70 Human_papillomavirus_type_16 R-HSA-8878171 Transcriptional regulation by RUNX1 161/4644 239/10654 5.841383853270349e-14 3.429063408426066e-13 1.2143286407150867e-13 1912/9070/5689/1437/5579/5682/1459/6045/9021/5929/27327/80012/1460/143471/5705/5709/5695/28996/1457/1911/6603/10413/5711/1387/3558/5683/10138/57332/5699/8312/5702/192669/83737/5371/57492/6688/4343/5696/5691/7314/55170/5718/84661/25/4773/8861/196528/5700/122706/5707/23198/86/100506658/865/7082/23309/51412/6714/2099/9861/8850/84733/5588/6604/8289/5698/5692/5713/6602/595/5710/3458/896/5719/23067/6233/161882/26523/5781/1493/23429/55193/6015/55904/6595/3562/6597/6929/8535/3674/3958/5706/6599/4331/57678/2623/5714/5688/5687/5708/6886/4602/5704/7311/7161/860/58508/25942/648/5694/6601/23466/4297/27161/894/5684/5720/902/2624/11091/640/8085/5690/2625/57690/5717/9491/4005/6598/10197/192670/5196/7316/10213/5079/10398/122809/5715/5701/5685/5686/2033/1021/84333/6605/50943/3065/861/23112/9757/5716/2811/9739/8784/3276/3559/7057/1022/5693/5721/1997 161 Human_papillomavirus_type_16 R-HSA-390466 Chaperonin-mediated protein folding 77/4644 95/10654 6.048144875132707e-14 3.535644691587995e-13 1.2520720969572972e-13 2788/6000/2780/9134/1459/2770/51807/10528/1460/10381/10576/1457/7846/7411/2782/81027/10574/54461/10693/2773/5201/2787/79861/5204/10575/10681/898/8786/2792/10471/26985/2785/10376/2783/26190/2784/10238/7157/2771/2791/5202/26224/84617/2629/8237/10382/7277/6774/26272/26270/347733/55135/2786/10383/60/84790/22948/7280/9628/10694/8841/54331/22803/59345/51764/94235/7203/908/55970/346562/11328/2793/6950/3801/55294/6499/2790 77 Human_papillomavirus_type_16 R-HSA-983169 Class I MHC mediated antigen processing & presentation 232/4644 371/10654 6.465118429950488e-14 3.763718322498147e-13 1.3328394404615115e-13 8454/8773/5689/127544/11065/9666/55070/5682/55819/3107/7321/9021/8697/10484/9817/7174/811/143471/5705/57674/10333/9690/8452/5709/9978/5695/567/4734/7337/7704/3106/3093/5711/23327/10616/5683/929/3309/25898/5699/7328/9632/7428/5702/22954/83737/51529/10075/29945/79176/8924/56658/51434/10425/25793/3133/51666/90293/54461/29882/7334/4591/3551/7332/5696/5691/9820/55658/7314/996/5718/8945/64410/10952/5700/122706/5707/23198/10533/51130/8517/6810/7323/22872/4008/7096/84861/11059/51444/51433/9861/55905/10134/6502/5698/27246/5692/5713/26190/79654/5710/9040/7324/5719/64682/8925/51191/6233/3685/26091/6047/868/6396/127247/1535/5930/26268/115290/51725/140459/23608/55585/51132/899/3135/23352/26224/142678/246184/151636/10193/821/2209/144699/5706/79876/26263/8881/57630/29927/7317/80196/84078/5714/26272/8651/5688/55336/5687/26270/118424/5708/55008/2923/10422/695/90933/63891/9246/10393/5704/9870/9520/4012/7327/51343/7311/9871/57520/5694/8673/3105/997/7325/140691/23643/57154/1147/5684/6737/8065/5720/84708/54850/7319/26046/991/10273/7320/5690/5717/9491/6500/26259/10197/7099/7336/4615/64750/23376/54778/7316/10213/222235/25831/7322/5715/5701/9341/23291/5685/5686/55521/55294/8453/80176/8139/126433/26267/5716/7064/3134/80204/27338/7097/23014/90678/5693/5721/51676/10427/4360 232 Human_papillomavirus_type_16 R-HSA-1852241 Organelle biogenesis and maintenance 192/4644 296/10654 6.564817293650577e-14 3.805966389666016e-13 1.347800679688157e-13 55763/5563/79738/79867/55735/79718/7531/11190/203068/54801/51807/85302/79441/53632/10381/5116/3313/5048/10576/5469/10989/22832/60412/192668/8655/6010/9702/132320/1432/1387/25813/7846/7840/6907/11064/84902/81027/2847/10499/23054/5518/1386/55835/85441/3054/23332/7019/93323/814/79861/3797/10575/1454/9321/23408/51422/10013/54806/5465/91147/54927/983/64784/79959/5310/4208/6604/8729/10376/10540/11336/117177/57545/26005/54930/54820/23322/6742/378/5600/1453/6300/801/9793/4218/140735/805/84617/5442/11258/22981/8636/54903/80776/79135/3842/3418/7532/55125/10382/6753/23410/121441/7277/26146/9814/4209/23354/2553/146057/9738/1639/55722/4957/50807/5566/5571/2551/7283/347733/22919/27077/22994/4867/6648/1069/5577/10383/5347/403/84790/22948/80184/22897/5564/23373/5565/5108/261734/57787/7280/10806/9657/1778/55770/23265/115106/10694/22995/55559/8841/55081/10142/6608/10640/51134/95681/200186/79989/7203/1781/80321/8766/9611/23409/79598/54205/149371/10121/347240/84131/6950/55212/3320/79600/10733/6256/4751/10498/80254/1385/26123/808/54536/9662/55142/8195/8648/8481/51259/55755/10891 192 Human_papillomavirus_type_16 R-HSA-5696400 Dual Incision in GG-NER 40/4644 41/10654 8.085061045182499e-14 4.66804141826792e-13 1.6530859057076628e-13 5982/7507/9978/2965/2067/2967/6117/10714/7314/6118/404672/9557/1643/5985/2068/5984/6233/5424/8451/54107/8450/5425/5111/2966/6119/5427/1642/142/2071/51426/7311/5983/10038/56655/57804/2072/7316/5426/2968/5981 40 Human_papillomavirus_type_16 R-HSA-5689880 Ub-specific processing proteases 150/4644 220/10654 9.284381282011694e-14 5.338519237156724e-13 1.8905211238608803e-13 5689/645836/5682/79594/7419/10474/7375/9817/91833/3091/143471/100287513/5705/8239/5709/5695/4792/9986/11047/4609/392188/4194/4089/100287144/5711/4088/5683/408/64135/5699/8312/100287327/5702/8900/57599/377630/6881/51616/728386/1540/100287404/5696/5691/7314/5718/90865/2648/5700/122706/5707/8737/55611/100287364/57646/23198/63967/9101/8517/993/890/7417/4092/1643/9861/23586/64426/100287441/7046/6502/5698/9146/5692/5713/5710/10454/7157/10869/9958/5719/6233/100287478/9804/23770/8607/7874/100287178/100287238/10600/23326/8237/4303/409/330/5706/27005/7416/25862/9738/8658/84132/5714/79589/55288/5688/9097/5687/5708/4087/63891/7189/5704/7311/367/5694/9960/23358/5684/8295/5720/7186/6885/991/5690/2625/5717/9491/4086/1080/57695/10197/64750/7316/10213/8678/9100/5715/5701/329/9099/5685/5686/5728/5716/9736/5693/154/10254/5721/100287205/4193 150 Human_papillomavirus_type_16 R-HSA-380108 Chemokine receptors bind chemokines 53/4644 59/10654 1.0626376900350066e-13 6.060490565524855e-13 2.1461916546706171e-13 729230/7852/1237/6349/3576/6360/2920/2921/1236/6370/58191/1524/643/2833/6347/6387/10663/3579/6367/2826/6376/6354/3627/6346/9034/51554/2829/1233/6366/6373/6357/6361/10803/6351/3577/10563/10850/5473/4283/6356/56477/1234/57007/6374/1230/2919/5196/6352/6348/6364/6372/6363/1232 53 Human_papillomavirus_type_16 R-HSA-5387390 Hh mutants abrogate ligand secretion 53/4644 59/10654 1.0626376900350066e-13 6.060490565524855e-13 2.1461916546706171e-13 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/9861/5698/5692/5713/5710/5719/6233/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 53 Human_papillomavirus_type_16 R-HSA-5617833 Cilium Assembly 139/4644 201/10654 1.3606958287709873e-13 7.728972663019009e-13 2.737048502790991e-13 55763/79738/79867/7531/11190/203068/54801/51807/85302/79441/10381/5116/5048/10576/22832/60412/192668/8655/6010/9702/132320/7846/7840/11064/84902/81027/2847/5518/55835/23332/93323/79861/3797/10575/1454/9321/10013/54806/91147/983/79959/5310/8729/10376/10540/11336/117177/57545/26005/54930/54820/23322/378/1453/9793/4218/140735/84617/11258/22981/8636/54903/80776/3842/7532/55125/10382/6753/121441/7277/26146/9814/23354/146057/9738/1639/55722/4957/50807/5566/7283/347733/22919/27077/22994/4867/1069/5577/10383/5347/403/84790/22948/80184/22897/5108/261734/57787/7280/10806/9657/1778/55770/23265/115106/10694/22995/55559/55081/10142/6608/10640/51134/95681/79989/7203/1781/80321/8766/79598/149371/10121/347240/84131/6950/55212/3320/79600/10733/4751/80254/26123/54536/9662/55142/8195/8481/51259/55755 139 Human_papillomavirus_type_16 R-HSA-1236975 Antigen processing-Cross presentation 79/4644 99/10654 1.4310442778097463e-13 8.095786781318846e-13 2.8669477891604427e-013 8773/5689/5682/3107/811/143471/5705/10333/5709/5695/567/3106/5711/5683/929/5699/5702/3133/3551/5696/5691/7314/5718/10952/5700/122706/5707/23198/8517/6810/7096/9861/5698/5692/5713/5710/5719/6233/3685/1535/3135/2209/5706/29927/5714/5688/5687/5708/2923/695/5704/4012/7311/5694/8673/3105/23643/1147/5684/5720/5690/5717/9491/10197/7099/4615/7316/10213/5715/5701/9341/5685/5686/5716/3134/7097/5693/5721/4360 79 Human_papillomavirus_type_16 R-HSA-5658442 Regulation of RAS by GAPs 59/4644 68/10654 1.4456429945604428e-13 8.145530607904825e-13 2.8845634894632384e-13 5689/4893/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/3845/3265/4763/5696/5691/7314/5718/5700/122706/5707/23198/5921/9861/5698/5692/5713/5710/5719/6233/9462/5706/84078/5714/5688/5687/5708/5704/7311/5694/5684/5720/153090/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721/161742 59 Human_papillomavirus_type_16 R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 42/4644 44/10654 2.022080361165577e-13 1.1347914986861219e-12 4.0186186546111684e-13 834/79370/55367/472/1387/51499/8738/7159/637/27166/23368/332/64065/8797/7157/604/63970/839/317/5875/55240/5366/84883/147923/843/94241/8626/7161/10397/8795/665/27113/9540/8793/835/58484/3486/355/8794/124446/5876/581 42 Human_papillomavirus_type_16 R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 54/4644 61/10654 2.5606544605338457e-13 1.4313140271430222e-12 5.068689055869051e-13 71/51517/147179/10094/8976/2885/3071/5879/26999/25/1072/10093/10006/4771/5594/4644/4641/10810/7410/7409/23191/10109/10787/5747/2209/10451/1793/6850/10152/10092/10163/55845/998/695/3326/10097/60/5058/63916/5595/3984/4690/4627/10458/919/10552/8936/917/3320/1398/10096/7454/9844/10095 54 Human_papillomavirus_type_16 R-HSA-4608870 Asymmetric localization of PCP proteins 56/4644 64/10654 2.794687539278925e-13 1.5559311974636236e-12 5.509993811777997e-13 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/1856/8322/23198/9861/5698/5692/5713/5710/5719/6233/7474/144165/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/50855/10197/64750/7316/10213/5715/5701/5685/5686/23513/5716/5693/5721 56 Human_papillomavirus_type_16 R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 49/4644 54/10654 3.695996419944886e-13 2.0495980146967095e-12 7.258208072452616e-13 2074/7507/5431/5435/9978/5433/10980/2965/5439/10987/2967/7314/404672/5438/2068/6233/7874/8451/10450/5434/100534599/5436/8450/4331/2966/1161/1642/2071/2873/7311/8533/5432/51138/9318/6917/5440/902/27339/5430/5441/7316/5437/2033/2968/56949/9716/57461/1022/50813 49 Human_papillomavirus_type_16 R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 38/4644 39/10654 4.089041374448194e-13 2.258631908799534e-12 7.998456397594479e-13 83990/5892/9156/1763/7486/5982/472/4683/84126/672/6117/83695/6118/5888/116028/5985/5984/5884/5810/80010/7516/580/11073/641/6119/3364/10524/144715/5889/1111/5983/5883/10111/675/545/5932/7156/5890 38 Human_papillomavirus_type_16 R-HSA-168325 Viral Messenger RNA Synthesis 41/4644 43/10654 4.4532950117001976e-13 2.4406144146153817e-12 8.642908081918148e-13 23165/348995/57122/5431/23511/5435/5433/23279/23225/5439/9972/8021/55746/5438/10762/79902/9883/6396/129401/4928/2963/5434/5903/55706/7175/5436/4927/2962/8086/5432/81929/5440/9631/5430/79023/5441/23636/53371/9688/5437/8480 41 Human_papillomavirus_type_16 R-HSA-5696395 Formation of Incision Complex in GG-NER 41/4644 43/10654 4.4532950117001976e-13 2.4406144146153817e-12 8.642908081918148e-13 6613/7507/9978/85015/2965/2067/2967/6612/6117/7334/7314/6118/404672/9557/1643/2068/6233/5886/8451/8554/8450/4331/2966/6119/1642/142/2071/1069/7329/7311/10038/902/7336/2072/54778/7316/7341/2968/5887/1022/7508 41 Human_papillomavirus_type_16 R-HSA-8939211 ESR-mediated signaling 150/4644 223/10654 5.138345880270249e-13 2.8050969922253538e-12 9.933644298535972e-13 5295/2788/374/3725/4893/857/7764/7031/2770/7039/27327/10274/5431/5435/5433/1509/5469/1105/4609/1387/8312/2782/5439/192669/10499/1386/4343/3845/904/3265/2773/2787/6387/1839/5290/4316/5594/2069/10681/51523/5481/5438/4313/865/1655/6667/2792/6714/2099/8850/10000/2785/595/2783/2784/2771/7514/1025/2353/255324/26523/801/2791/2957/805/5170/2963/3838/5434/5590/6464/7090/5241/5747/5436/1903/3315/4318/5885/57678/7033/2962/8503/10524/8243/4602/2786/208/3326/23030/6908/1956/5536/3169/858/5432/3480/10728/5595/7528/3727/27161/2354/596/5440/685/54331/2309/9687/59345/8204/5430/207/5451/2625/57690/1027/51764/94235/5441/10735/192670/2100/1950/55970/4314/346562/2289/7391/5437/2793/3320/2033/4846/9126/3065/2002/2066/861/23028/23112/10498/1385/5296/808/3276/8202/8648/2288/2790 150 Human_papillomavirus_type_16 R-HSA-448424 Interleukin-17 signaling 61/4644 72/10654 5.472585055020446e-13 2.9759832682921265e-12 1.0538801085147492e-12 8454/3605/3725/9252/4790/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/23118/8517/5528/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/79155/7867/64127/5602/3656/7189/112744/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/7316/4205/23291/2002/5609/1385/5599 61 Human_papillomavirus_type_16 R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 46/4644 50/10654 5.759525939373918e-13 3.1199285300932846e-12 1.104855209666527e-12 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/2209/5706/5714/5688/5687/5708/5704/5694/5684/5720/5690/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721/4360 46 Human_papillomavirus_type_16 R-HSA-111885 Opioid Signalling 73/4644 91/10654 7.420984772078313e-13 4.004477552009951e-12 1.418099114340471e-12 2788/2780/5331/2770/817/5578/5582/5530/107/4988/2782/5499/5518/814/2773/5515/2787/818/5567/5594/10681/112/5573/5528/111/5443/2792/5519/2785/2783/2784/5613/2771/5580/196883/115/801/2791/805/3838/5568/113/10645/5566/84254/816/2786/5577/1020/109/5516/815/5321/54331/5575/59345/5532/51764/94235/114/108/5173/55970/10768/346562/2793/5576/5534/1385/5144/808/5137/2790 73 Human_papillomavirus_type_16 R-HSA-109606 Intrinsic Pathway for Apoptosis 48/4644 53/10654 7.748458537332299e-13 4.165167558573645e-12 1.4750040046867698e-12 7531/55075/10971/7533/2810/1869/8655/836/840/7159/637/578/23368/7027/5594/841/7534/4836/22900/598/10000/708/3002/7157/7029/331/57099/317/140735/1029/7532/6774/5366/56616/8626/208/7161/7529/5595/27113/596/10018/842/207/54205/5534/581/5599 48 Human_papillomavirus_type_16 R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 40/4644 42/10654 9.795981679156942e-13 5.245710799945492e-12 1.8576550231265877e-12 23165/348995/57122/23511/81608/23279/23225/9972/8021/55746/53981/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/7884/4927/10898/10482/51692/8086/22916/81929/9631/29894/79023/23636/4686/8189/53371/9688/10189/8480/55339 40 Human_papillomavirus_type_16 R-HSA-5632684 Hedgehog 'on' state 69/4644 85/10654 1.0800442249323171e-12 5.761604743650346e-12 2.040347705295392e-12 5689/5682/22873/1452/51684/143471/5705/8452/5709/9978/5695/5711/5683/408/5699/5702/83737/6469/5696/5691/7314/5718/5700/122706/5707/23198/2737/5727/8650/9861/8405/5698/5692/5713/5710/5719/6233/409/79577/5706/5714/2736/5688/5687/5708/5704/7311/5694/57154/5684/5720/2735/6608/5690/5717/9491/10197/64750/132884/7316/10213/5715/5701/5685/5686/5716/5693/2622/5721 69 Human_papillomavirus_type_16 R-HSA-9614085 FOXO-mediated transcription 56/4644 65/10654 1.1610156814425866e-12 6.127316806335807e-12 2.1698567225047838e-12 2308/857/2290/65018/57060/356/10971/7295/2810/4089/1647/1387/4088/10628/4801/3630/56729/23411/7534/847/5934/5443/8850/10000/3066/604/5105/7532/4303/23410/4287/4800/901/9314/10370/2908/6794/4852/6648/4087/208/25942/7529/27113/2309/10018/4802/207/1027/6720/1649/1026/2033/3065/91584/10891 56 Human_papillomavirus_type_16 R-HSA-113418 Formation of the Early Elongation Complex 33/4644 33/10654 1.1791700197510106e-12 6.127316806335807e-12 2.1698567225047838e-12 5431/5435/5433/2965/5439/2967/51497/404672/5438/2068/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/7469/4686/9150/5437/6827/2968/1022 33 Human_papillomavirus_type_16 R-HSA-163359 Glucagon signaling in metabolic regulation 33/4644 33/10654 1.1791700197510106e-12 6.127316806335807e-12 2.1698567225047838e-12 2788/107/2782/2787/5567/112/5573/111/2785/2783/2784/196883/115/2791/5568/2642/113/5566/2641/2786/5577/109/54331/5575/59345/51764/94235/114/108/55970/2778/5576/2790 33 Human_papillomavirus_type_16 R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 33/4644 33/10654 1.1791700197510106e-12 6.127316806335807e-12 2.1698567225047838e-12 5431/5435/5433/2965/5439/2967/51497/404672/5438/2068/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/7469/4686/9150/5437/6827/2968/1022 33 Human_papillomavirus_type_16 R-HSA-420092 Glucagon-type ligand receptors 33/4644 33/10654 1.1791700197510106e-12 6.127316806335807e-12 2.1698567225047838e-12 2788/2692/2740/2696/117/2782/2787/10681/2792/2785/2783/2784/2791/6343/9340/116/6344/2642/2641/2786/7432/54331/59345/7433/51764/94235/2695/55970/2778/2691/2793/7434/2790 33 Human_papillomavirus_type_16 R-HSA-68962 Activation of the pre-replicative complex 33/4644 33/10654 1.1791700197510106e-12 6.127316806335807e-12 2.1698567225047838e-12 5422/4174/84515/4998/10926/990/55388/6117/5001/5558/6118/23594/5557/4175/23649/4999/4172/5000/8318/54107/4173/51053/6119/5427/81620/29935/23595/4176/56655/1017/8317/5426/4171 33 Human_papillomavirus_type_16 R-HSA-9022692 Regulation of MECP2 expression and activity 33/4644 33/10654 1.1791700197510106e-12 6.127316806335807e-12 2.1698567225047838e-12 2290/79718/817/9212/27327/28996/9612/6907/192669/4204/4343/814/818/3066/26523/801/805/3930/5566/816/25942/27161/815/8841/57690/192670/9611/2874/3064/3065/23112/1385/808 33 Human_papillomavirus_type_16 R-HSA-4615885 SUMOylation of DNA replication proteins 42/4644 45/10654 1.7491724269493584e-12 9.055678653173248e-12 3.2068727345896183e-12 23165/9212/348995/6613/57122/23511/6790/23279/23225/9972/6612/8021/55746/7150/51588/3619/7153/332/10762/79902/9883/7155/6396/129401/4928/5903/55706/7175/5111/4927/8086/7329/5905/81929/55143/9631/79023/23636/53371/9688/7341/8480 42 Human_papillomavirus_type_16 R-HSA-5685938 HDR through Single Strand Annealing (SSA) 36/4644 37/10654 2.061800696769824e-12 1.0634949917529645e-11 3.7661374956476665e-12 83990/9156/1763/7486/5982/472/4683/84126/2067/672/6117/83695/6118/25/5888/116028/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/5983/5893/5883/10111/545/2072/5932/7156 36 Human_papillomavirus_type_16 R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 39/4644 41/10654 2.1521660995645365e-12 1.1060399405454377e-11 3.916801229976716e-12 23165/348995/57122/23511/81608/23279/23225/9972/8021/55746/53981/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10898/10482/51692/8086/22916/81929/9631/29894/79023/23636/4686/8189/53371/9688/10189/8480/55339 39 Human_papillomavirus_type_16 R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 44/4644 48/10654 2.595013458098366e-12 1.3239286842589117e-11 4.6884070898466174e-12 5295/5777/1437/5291/6776/3558/3717/2534/3563/2885/9846/1399/7314/5290/7534/3718/3567/6233/7525/7409/6777/5781/3562/6464/1438/6850/5566/8503/2889/4067/3636/6654/3716/7311/5293/3561/3568/7316/3560/3055/867/1398/5296/3559 44 Human_papillomavirus_type_16 R-HSA-73893 DNA Damage Bypass 44/4644 48/10654 2.595013458098366e-12 1.3239286842589117e-11 4.6884070898466174e-12 56852/5982/9978/25898/57599/6117/10714/55666/7314/51514/6118/9636/11201/51455/5985/5984/6233/5424/8451/124739/54107/7706/8450/5425/5111/6119/5427/1642/5429/9246/51426/7311/5983/56655/57804/7320/7316/5426/9100/10459/7415/7398/5981/5980 44 Human_papillomavirus_type_16 R-HSA-2871796 FCERI mediated MAPK activation 32/4644 32/10654 2.715772755809888e-12 1.3755339987008204e-11 4.8711561495051e-12 3725/4893/5335/2885/3845/3265/5062/5879/5601/5336/5594/4214/7410/7409/2353/6464/2205/3937/10451/2206/6850/4067/5602/6654/5058/6416/5595/9402/27040/5609/5599/2207 32 Human_papillomavirus_type_16 R-HSA-69190 DNA strand elongation 32/4644 32/10654 2.715772755809888e-12 1.3755339987008204e-11 4.8711561495051e-12 2237/1763/5982/5422/4174/84515/84296/6117/10714/5558/6118/64785/3978/5557/5985/4175/5984/23649/5424/4172/8318/4173/5425/5111/6119/51659/5983/4176/57804/9837/4171/5981 32 Human_papillomavirus_type_16 R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 64/4644 78/10654 2.8375371097933212e-12 1.4320376133237517e-11 5.071251479827519e-12 3443/4790/7321/9474/4792/3093/1387/64135/83737/7187/1540/3551/7314/3445/8737/29110/4214/9636/841/8517/3444/8887/7323/5970/23586/7128/3451/3448/3661/3439/51191/6233/10010/55593/84282/8772/3452/4791/3446/3665/351/7706/843/3440/9246/7189/7311/5094/9641/3456/1147/3441/7186/57506/3449/7316/4793/3146/7322/2033/6288/54941/6285/5300 64 Human_papillomavirus_type_16 R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 46/4644 51/10654 3.385092794230211e-12 1.7022527563817154e-11 6.028159965578795e-12 5689/5682/143471/5705/5709/5695/5711/4946/5683/5699/5702/5696/5691/5718/1728/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/5706/5714/5688/5687/5708/5704/5694/5684/5720/5690/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 46 Human_papillomavirus_type_16 R-HSA-451927 Interleukin-2 family signaling 41/4644 44/10654 3.7679895235673495e-12 1.8880318934160685e-11 6.686056598209734e-12 5295/5777/1437/5291/6776/84868/3558/3717/3563/2885/9846/3600/5290/50615/3718/3567/3932/6777/59067/3562/6464/6775/1438/3581/6774/6850/6772/8503/3636/6654/3716/5293/2185/6655/3561/3578/3568/3560/5296/3559/3601 41 Human_papillomavirus_type_16 R-HSA-182971 EGFR downregulation 31/4644 31/10654 6.2539895913653866e-12 3.122543557539373e-11 1.1057812650775287e-11 374/7039/6456/30011/2885/8874/10252/7314/1839/8027/2060/2069/9146/6455/6233/29924/255324/5782/5796/998/7311/1956/10253/685/58513/7316/1950/867/5774/10254/6457 31 Human_papillomavirus_type_16 R-HSA-6806834 Signaling by MET 64/4644 79/10654 8.590640908291889e-12 4.2739961682033766e-11 1.5135433029913296e-11 5295/3675/4893/5770/3249/5908/3082/1280/1289/3688/3910/1290/6456/30011/2885/3845/3265/1399/7314/5879/3918/5290/8027/2060/284217/9101/6714/9146/6455/2335/64759/84951/6233/5781/1302/6464/85440/5747/382/1277/3912/6774/4233/5795/2889/5771/3913/6654/5867/7311/2549/26018/10048/7316/1301/1281/867/3914/1398/5906/23163/1278/10254/6457 64 Human_papillomavirus_type_16 R-HSA-5358346 Hedgehog ligand biogenesis 55/4644 65/10654 8.654164565317524e-12 4.2903861784948714e-11 1.5193474706452937e-11 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/6868/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/9861/5698/5692/5713/5710/5719/6233/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721/5034 55 Human_papillomavirus_type_16 R-HSA-190236 Signaling by FGFR 69/4644 87/10654 8.7183337887311e-12 4.3069796850668075e-11 1.5252237021056633e-11 5295/4893/2250/5335/54845/5431/5435/5433/9965/5439/2264/2885/7073/5518/2252/2253/3845/3265/7314/5515/5290/8823/5594/2260/5438/3185/2249/6714/2248/4670/2247/6233/2246/2251/5781/5725/2963/5434/6464/5436/673/2263/2962/6654/7311/2549/5432/22916/5595/5516/8822/10253/5440/5430/3178/8817/5441/2254/4686/7316/26281/10818/2261/867/5437/2255/27006/3187/161742 69 Human_papillomavirus_type_16 R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 193/4644 309/10654 1.0223223338119833e-11 5.032695559081447e-11 1.7822202827673358e-11 8454/5689/127544/11065/9666/55070/5682/55819/7321/9021/8697/9817/7174/143471/5705/57674/9690/8452/5709/9978/5695/4734/7337/7704/3093/5711/23327/10616/5683/25898/5699/7328/7428/5702/22954/83737/51529/10075/29945/79176/8924/56658/51434/10425/25793/51666/90293/54461/29882/7334/4591/7332/5696/5691/9820/55658/7314/996/5718/8945/64410/5700/122706/5707/23198/10533/51130/7323/4008/84861/11059/51444/51433/9861/55905/6502/5698/27246/5692/5713/26190/79654/5710/9040/7324/5719/64682/8925/51191/6233/26091/6047/868/127247/5930/26268/115290/51725/140459/23608/55585/51132/899/23352/26224/142678/246184/151636/10193/144699/5706/79876/26263/8881/57630/7317/80196/84078/5714/26272/8651/5688/55336/5687/26270/118424/5708/55008/10422/90933/63891/9246/10393/5704/9870/9520/4012/7327/51343/7311/57520/5694/997/7325/140691/57154/5684/6737/8065/5720/84708/54850/7319/26046/991/10273/7320/5690/5717/9491/6500/26259/10197/7336/64750/23376/54778/7316/10213/222235/25831/7322/5715/5701/23291/5685/5686/55521/55294/8453/80176/8139/126433/26267/5716/7064/80204/27338/23014/90678/5693/5721/51676 193 Human_papillomavirus_type_16 R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 30/4644 30/10654 1.4400170225111794e-11 7.039525723286358e-11 2.492895780763898e-11 56852/5982/9978/57599/6117/10714/7314/51514/6118/5985/5984/6233/5424/8451/54107/8450/5425/5111/6119/5427/1642/7311/5983/56655/57804/7320/7316/5426/7398/5981 30 Human_papillomavirus_type_16 R-HSA-180786 Extension of Telomeres 30/4644 30/10654 1.4400170225111794e-11 7.039525723286358e-11 2.492895780763898e-11 2237/1763/5982/5422/6117/10714/5558/6118/3978/5557/5985/5984/23649/8607/5424/55651/54107/5425/5111/6119/5427/55135/5983/56655/7015/57804/10856/5426/1736/5981 30 Human_papillomavirus_type_16 R-HSA-73856 RNA Polymerase II Transcription Termination 56/4644 67/10654 1.5449547470966487e-11 7.526289965890966e-11 2.6652728093187797e-11 8683/6431/51585/199746/81608/1477/65109/9877/53981/7919/6432/6430/134353/11051/8106/22794/9785/11338/4116/1478/10250/51362/23283/6636/10914/84324/6635/7884/6428/10212/84967/6637/55110/6429/10898/10569/9295/51692/9939/6426/22916/1479/10921/79869/29894/4686/8189/10978/7307/9984/10189/6634/9775/6427/55339/6628 56 Human_papillomavirus_type_16 R-HSA-186797 Signaling by PDGF 50/4644 58/10654 1.8509779292172914e-11 8.985889393397439e-11 3.1821583776746004e-11 5295/4893/5335/5291/256076/1280/1289/6696/6776/1290/2885/8440/9564/3845/1285/3265/1399/56034/5290/5340/1284/5921/6778/6714/1292/5154/1293/6777/5781/1291/1286/1287/80310/5782/6774/6772/2889/5159/2886/6654/1282/4690/1299/1281/1398/5155/5296/131873/7057/5156 50 Human_papillomavirus_type_16 R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 61/4644 75/10654 1.9299290884661243e-11 9.336863831441284e-11 3.306448383869367e-11 23165/8683/6431/199746/348995/57122/23511/65109/23279/23225/9877/9972/8021/55746/7919/6432/6430/56001/10762/22794/9785/11338/4116/79902/9883/10250/51362/6396/129401/2733/84324/4928/5903/55706/7175/6428/10212/55110/6429/4927/10569/9295/10482/8086/9939/6426/22916/10921/81929/9631/79023/23636/4686/53371/7307/9688/9984/10189/9775/6427/8480 61 Human_papillomavirus_type_16 R-HSA-391251 Protein folding 77/4644 101/10654 2.0420656436140432e-11 9.845423017149493e-11 3.4865436201332194e-11 2788/6000/2780/9134/1459/2770/51807/10528/1460/10381/10576/1457/7846/7411/2782/81027/10574/54461/10693/2773/5201/2787/79861/5204/10575/10681/898/8786/2792/10471/26985/2785/10376/2783/26190/2784/10238/7157/2771/2791/5202/26224/84617/2629/8237/10382/7277/6774/26272/26270/347733/55135/2786/10383/60/84790/22948/7280/9628/10694/8841/54331/22803/59345/51764/94235/7203/908/55970/346562/11328/2793/6950/3801/55294/6499/2790 77 Human_papillomavirus_type_16 R-HSA-2132295 MHC class II antigen presentation 90/4644 123/10654 2.201367481412596e-11 1.0577118412403671e-10 3.745657718914006e-11 64837/162/51807/10484/1174/1785/10381/1780/3115/1509/8655/84516/832/285643/3113/10112/7846/5476/3117/9632/81027/6456/11004/163/1759/3127/81930/51164/161/79861/3797/10053/29127/3126/22872/3796/10437/89953/56992/10376/10540/3835/1213/1211/9493/6396/1175/7879/140735/8907/1508/3120/1173/84617/11258/6712/1783/10382/93661/821/55860/830/3123/3832/7277/160/10671/3122/1639/26052/1062/347733/51143/9871/10383/24137/84790/84643/8905/3125/7280/829/1778/164/3119/1781/10121/3799/375/10427 90 Human_papillomavirus_type_16 R-HSA-3232142 SUMOylation of ubiquitinylation proteins 36/4644 38/10654 2.264021966071183e-11 1.0804159246251258e-10 3.8260593196763286e-11 23165/348995/57122/23511/23279/23225/7428/5371/9972/8021/55746/51588/10762/79902/9883/9063/6396/129401/8554/4928/5903/55706/7175/4927/8086/7329/81929/9631/79023/23636/53371/9688/7341/5987/8480/4193 36 Human_papillomavirus_type_16 R-HSA-420499 Class C/3 (Metabotropic glutamate/pheromone receptors) 36/4644 38/10654 2.264021966071183e-11 1.0804159246251258e-10 3.8260593196763286e-11 50833/5726/2550/50832/259294/2912/259295/9568/2911/2914/259296/259289/50835/338398/2916/259293/54429/80835/50840/2913/2918/50838/83756/259286/259287/50836/846/259290/80834/259292/50834/259285/2917/50831/50839/50837 36 Human_papillomavirus_type_16 R-HSA-2408522 Selenoamino acid metabolism 87/4644 118/10654 2.3995189534407524e-11 1.1411949463313139e-10 4.0412950794791615e-11 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/6208/6170/7296/6203/6147/191/6222/4837/6134/6155/6231/6142/9061/23521/6207/6233/6188/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/9060/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/875/6164/6209/11224/6130/6204/6228/7965/6124/6189/6135/6201/6161/6133 87 Human_papillomavirus_type_16 R-HSA-418597 G alpha (z) signalling events 43/4644 48/10654 3.0413343851059493e-011 1.4415513994269076e-10 5.104942495625918e-11 2788/5579/2770/5578/5582/5583/107/2782/6004/2773/2787/10681/112/111/2792/5588/2785/2783/2784/2771/5580/196883/115/5999/2791/150/113/2786/109/151/54331/59345/51764/94235/114/108/55970/2778/346562/152/2793/5581/2790 43 Human_papillomavirus_type_16 R-HSA-186763 Downstream signal transduction 29/4644 29/10654 3.3153154635278996e-11 1.5661237694712603e-10 5.5460886010461414e-11 5295/4893/5335/5291/6776/2885/8440/9564/3845/3265/1399/5290/5921/6778/6714/5154/6777/5781/6774/6772/2889/5159/2886/6654/4690/1398/5155/5296/5156 29 Human_papillomavirus_type_16 R-HSA-73887 Death Receptor Signalling 100/4644 141/10654 3.662999688611135e-11 1.7245599205105442e-10 6.107155962643785e-11 7124/25999/7984/4790/7531/29/356/7375/9530/8878/1894/23385/10276/4792/8439/9138/836/23365/10616/3654/6868/8997/8874/1540/3551/7314/5879/257397/9181/90268/81858/8737/8767/55072/23118/841/8517/8887/6453/9828/5970/8797/7128/396/10454/3066/6233/7410/7409/6610/26574/8772/331/8717/8743/5663/84894/84888/56928/7204/27237/7074/330/10451/27005/843/8837/11108/8567/7189/6654/7311/387/6655/8795/1147/4804/57142/8841/7186/56957/6885/5584/10018/8793/835/355/23421/4615/7316/4168/7132/329/9099/4803/3065/55512/5599/7185/10672 100 Human_papillomavirus_type_16 R-HSA-447115 Interleukin-12 family signaling 49/4644 57/10654 3.689675784133979e-11 1.7313094064013287e-10 6.131057807115784e-11 3593/5908/1265/3313/6175/3717/3181/4001/3594/4282/5062/3572/1072/3592/6627/9049/27250/9987/3185/149233/3458/5478/302/552900/51561/7297/6775/3595/821/4478/6774/6772/998/6648/3716/2939/6888/246778/3586/829/5055/6647/6950/9466/4507/6845/375/5721/5034 49 Human_papillomavirus_type_16 R-HSA-1839126 FGFR2 mutant receptor activation 32/4644 33/10654 5.1887060309694267e-11 2.418523110116314e-10 8.564676505044832e-11 2250/5431/5435/5433/5439/2252/2253/8823/5438/2249/2248/2247/2246/2251/2963/5434/5436/2263/2962/5432/22916/8822/5440/5430/8817/5441/2254/4686/26281/5437/2255/27006 32 Human_papillomavirus_type_16 R-HSA-5357905 Regulation of TNFR1 signaling 32/4644 33/10654 5.1887060309694267e-11 2.418523110116314e-10 8.564676505044832e-11 7124/25999/7375/10616/1540/3551/7314/90268/81858/8737/55072/841/8517/8887/7128/6233/331/8717/84888/56928/330/27005/8567/7311/1147/7186/56957/7316/7132/329/9099/7185 32 Human_papillomavirus_type_16 R-HSA-437239 Recycling pathway of L1 42/4644 47/10654 6.293140747565375e-11 2.9139526299782907e-10 1.031913299583414e-10 9252/71/7430/51807/1785/10381/285643/7846/1808/81027/6456/5962/163/6196/1759/6197/8986/161/79861/5594/8650/6714/10376/6195/1213/1211/1175/1173/84617/10382/7277/4478/160/26052/27330/347733/3897/10383/24137/60/84790/7280 42 Human_papillomavirus_type_16 R-HSA-4570464 SUMOylation of RNA binding proteins 42/4644 47/10654 6.293140747565375e-11 2.9139526299782907e-10 1.031913299583414e-10 1912/23165/6045/80012/348995/6613/57122/23511/3190/1911/23279/23225/57332/9972/8021/55746/10762/79902/9883/84733/6396/129401/7703/6015/4928/5903/55706/7175/8535/4927/8086/7329/648/81929/9631/79023/23636/3183/53371/9688/7341/8480 42 Human_papillomavirus_type_16 R-HSA-8986944 Transcriptional Regulation by MECP2 52/4644 62/10654 6.437158337121007e-11 2.970833272033149e-10 1.052056348726148e-10 627/2290/79718/5770/817/9212/27327/6657/28996/9612/4988/6907/192669/4204/3654/4343/6750/814/818/6446/54487/4208/3066/26523/801/2891/805/2904/3930/4233/5566/1392/816/25942/27161/815/8841/5468/4986/57690/192670/114787/9611/2874/2289/2903/3064/5728/3065/23112/1385/808 52 Human_papillomavirus_type_16 R-HSA-2428924 IGF1R signaling cascade 46/4644 53/10654 7.379805172745678e-11 3.3947103794630115e-10 1.2021632585111166e-10 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/54106/5290/3667/8823/57761/2260/2249/2248/2247/8471/2246/2251/5781/5170/6464/2322/2263/3481/208/6654/2549/3480/8822/8817/2254/5289/26281/10818/2261/2255/27006/3479/5296 46 Human_papillomavirus_type_16 R-HSA-350054 Notch-HLH transcription pathway 28/4644 28/10654 7.631833213918448e-11 3.487772638152307e-10 1.2351192446320958e-10 79718/9759/9612/22938/1387/6907/4853/9794/79885/2648/9734/55869/51564/55534/84441/10013/83933/4854/8850/3066/10046/10014/4855/4851/8841/9611/3065/3516 28 Human_papillomavirus_type_16 R-HSA-69205 G1/S-Specific Transcription 28/4644 28/10654 7.631833213918448e-11 3.487772638152307e-10 1.2351192446320958e-10 5422/1869/4998/5928/990/8900/6241/7027/898/5934/1876/983/7298/7029/1719/26271/8318/286826/5111/91750/1874/81620/55957/1875/5933/3065/7083/132660 28 Human_papillomavirus_type_16 R-HSA-168276 NS1 Mediated Effects on Host Pathways 37/4644 40/10654 7.972129202727736e-11 3.631460153060719e-10 1.2860030702964768e-10 3839/23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/402569/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/4927/10898/3840/8086/3837/81929/9631/79023/23636/53371/9688/8480 37 Human_papillomavirus_type_16 R-HSA-177243 Interactions of Rev with host cellular proteins 34/4644 36/10654 1.0790389499448975e-10 4.87198044120233e-10 1.7253064997917997e-10 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/5902/7514/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/1104/5905/3837/81929/9631/79023/23636/53371/9688/8480 34 Human_papillomavirus_type_16 R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 34/4644 36/10654 1.0790389499448975e-10 4.87198044120233e-10 1.7253064997917997e-10 71/51517/147179/10094/8976/2885/3071/5879/26999/25/10093/10006/5594/10810/23191/10109/10787/5747/10152/10092/10163/55845/998/695/10097/60/5595/4690/10458/10552/8936/10096/7454/10095 34 Human_papillomavirus_type_16 R-HSA-1433557 Signaling by SCF-KIT 39/4644 43/10654 1.0799614520412863e-10 4.87198044120233e-10 1.7253064997917997e-10 5295/5777/4893/5578/6776/3717/2534/2885/9846/3845/3265/5879/5290/3815/9306/6714/7525/7409/3932/6777/5781/10019/2241/4318/6774/6772/8651/8503/4067/1111/2886/6654/9402/867/4254/5296/10076/2887/2242 39 Human_papillomavirus_type_16 R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 31/4644 32/10654 1.1593871149358486e-10 5.196869400175705e-10 1.8403588977626386e-10 892/4609/4089/22938/4088/1030/904/7314/5054/7027/6667/4092/7050/6233/1025/7029/4221/3726/1024/60436/8812/1874/905/4087/7311/54778/7316/1875/5933/3065/25937 31 Human_papillomavirus_type_16 R-HSA-5673000 RAF activation 31/4644 32/10654 1.1593871149358486e-10 5.196869400175705e-10 1.8403588977626386e-10 4893/5526/817/5605/3717/4296/5894/5518/4140/3845/3265/5515/818/8844/5528/6714/5519/369/801/805/673/5529/816/7529/5516/815/5604/5525/5527/808/5245 31 Human_papillomavirus_type_16 R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 47/4644 55/10654 1.4535881748634362e-10 6.494854169851595e-10 2.3000121305247805e-10 834/4790/7295/29108/1432/10628/5603/83737/3654/7334/1540/3551/7314/257397/8767/23118/841/8517/5970/7128/837/598/10454/6233/5600/6300/5608/4791/351/330/64127/3656/7189/3326/4210/7311/114548/1147/596/6885/842/10392/10910/835/58484/7316/329 47 Human_papillomavirus_type_16 R-HSA-2428928 IRS-related events triggered by IGF1R 45/4644 52/10654 1.48055447085845e-10 6.573474438653182e-10 2.3278537982851047e-10 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/54106/5290/3667/8823/57761/2260/2249/2248/2247/8471/2246/2251/5781/5170/2322/2263/3481/208/6654/2549/3480/8822/8817/2254/5289/26281/10818/2261/2255/27006/3479/5296 45 Human_papillomavirus_type_16 R-HSA-2980766 Nuclear Envelope Breakdown 45/4644 52/10654 1.48055447085845e-10 6.573474438653182e-10 2.3278537982851047e-10 23165/5579/91754/5578/348995/57122/23511/23279/23225/9663/4001/9972/8021/55746/10762/983/79902/9883/7444/2010/64900/23175/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/5347/7112/4000/81929/9631/140609/79023/23636/7443/53371/9688/8815/8480 45 Human_papillomavirus_type_16 R-HSA-5693538 Homology Directed Repair 97/4644 138/10654 1.6244811564770982e-10 7.189738367625769e-10 2.5460903398877315e-10 2237/83990/151987/5892/9156/1763/7486/5982/472/6613/80198/4683/165918/84126/8900/8924/2067/672/6117/7334/10714/348654/83695/7314/6118/25/5888/51588/51720/63967/5531/116028/890/197342/7517/9656/84464/5985/5984/6233/7158/6047/5884/5810/5424/80010/7516/7515/54107/580/11073/5425/641/5111/6119/3364/10524/5427/144715/5889/5429/142/1111/7329/79728/51426/146956/7311/3980/5983/10038/56655/51750/1017/54962/5893/5883/10111/57804/675/51548/545/7336/2072/29086/7316/5426/10635/7341/8914/23514/5932/9025/79184/7156/5890/5981 97 Human_papillomavirus_type_16 R-HSA-1538133 G0 and Early G1 27/4644 27/10654 1.756627497602584e-10 7.750152135649136e-10 2.744548754943462e-10 9134/1869/4609/5928/990/8900/7027/7153/898/5934/993/890/983/7029/1859/286826/5111/91750/1874/55957/1017/4605/4149/1875/5933/3065/132660 27 Human_papillomavirus_type_16 R-HSA-168253 Host Interactions with Influenza Factors 38/4644 42/10654 2.2613491627115786e-10 9.945682994621772e-10 3.52204852268558e-10 3839/23165/348995/57122/23511/23279/23225/3836/9972/8021/7040/55746/402569/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/4927/10898/3840/8086/3837/81929/9631/79023/23636/53371/9688/8480 38 Human_papillomavirus_type_16 R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 33/4644 35/10654 2.349983046288111e-10 1.0303206918569437e-9 3.648657887657857e-10 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/7884/4927/10482/8086/22916/81929/9631/79023/23636/4686/53371/9688/10189/8480 33 Human_papillomavirus_type_16 R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 46/4644 54/10654 2.8722151822143695e-10 1.251465186536261e-9 4.431793285404323e-10 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/54106/5290/3667/8823/57761/2260/2249/2248/2247/8471/2246/2251/5781/5170/6464/2322/2263/3481/208/6654/2549/3480/8822/8817/2254/5289/26281/10818/2261/2255/27006/3479/5296 46 Human_papillomavirus_type_16 R-HSA-74751 Insulin receptor signalling cascade 46/4644 54/10654 2.8722151822143695e-10 1.251465186536261e-9 4.431793285404323e-10 5295/4893/2250/5291/9965/2264/3630/2885/8660/9846/2252/2253/3845/3265/54106/5290/3667/8823/5594/57761/2260/2249/2248/2247/2246/2251/5781/5170/6464/2322/2263/208/6654/2549/5595/8822/8817/2254/5289/26281/10818/2261/2255/27006/5296/2887 46 Human_papillomavirus_type_16 R-HSA-76002 Platelet activation, signaling and aggregation 164/4644 262/10654 2.943320421717527e-10 1.278476331786282e-9 4.52744741421109e-10 5295/2788/2149/5777/5579/5770/5291/7042/64805/2770/5175/3959/5578/5582/5908/3082/388/5583/2769/7423/1432/3920/3309/2534/3690/408/2768/2782/87/5894/10487/2885/7040/9564/54863/350/7043/2773/5879/5054/2787/5099/1072/5290/7018/5340/5336/813/7094/5594/10681/7414/10490/7534/6810/7123/2792/6714/7273/22927/1191/9749/27154/226/5588/5880/2335/5294/2785/2783/2784/1445/8525/5478/2771/7410/5580/7409/5154/3932/7076/801/5781/2151/2791/805/5170/5590/351/6464/135228/5747/3937/7424/2316/3674/409/6915/7277/10451/334/1277/150/335/308/6850/8503/6403/197/4067/81/9948/998/3481/2786/6654/5473/8407/387/29789/10916/5595/151/5321/54331/59345/1606/207/7422/51764/94235/5196/3827/1950/55970/5216/2767/346562/152/6647/27040/2793/7078/55664/391/5345/2/1398/88/2811/5906/3479/5155/5296/5581/808/213/5660/9630/7057/1278/2207/2790/10672 164 Human_papillomavirus_type_16 R-HSA-111996 Ca-dependent events 35/4644 38/10654 3.6242002461795726e-10 1.559740167297528e-9 5.523482454623049e-10 817/5578/5582/107/814/818/5567/5594/112/5573/111/5613/5580/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5321/5575/114/108/5576/1385/808/5137 35 Human_papillomavirus_type_16 R-HSA-5655302 Signaling by FGFR1 in disease 35/4644 38/10654 3.6242002461795726e-10 1.559740167297528e-9 5.523482454623049e-10 5295/4893/11052/2250/5335/9530/613/6776/11064/2885/9846/2253/3845/3265/7750/8805/5290/2260/2249/399687/2247/2246/2251/6777/1523/9208/6774/6772/6654/11160/2549/8822/2254/26281/10818 35 Human_papillomavirus_type_16 R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 35/4644 38/10654 3.6242002461795726e-10 1.559740167297528e-9 5.523482454623049e-10 1912/1459/6045/80012/1460/28996/1457/1911/6603/10138/57332/57492/196528/86/865/51412/84733/6604/8289/6602/23429/55193/6015/6595/6597/8535/6599/648/6601/23466/6598/2033/84333/6605/861 35 Human_papillomavirus_type_16 R-HSA-9006931 Signaling by Nuclear Receptors 183/4644 299/10654 4.036494751929033e-10 1.731866096928573e-9 6.133029206214401e-10 5295/2788/374/3725/4893/857/7764/79718/7031/5160/5165/2770/10901/7039/27327/10274/5915/1381/5431/5435/5433/1509/5469/1105/9612/4609/55818/1387/6907/8312/2782/5439/192669/10499/1386/5914/4343/3845/904/1071/3265/2773/10062/2787/6387/1839/5290/4316/5594/2069/10681/51523/5481/5438/348/4313/865/1655/6667/2792/6714/2099/8850/5467/10000/2785/595/2783/2784/2771/7514/1025/2353/6257/255324/26523/801/2791/2957/805/5105/5170/2963/3838/5434/5590/6464/112724/1374/7090/5241/6319/5747/5436/1903/3315/4318/5885/19/57678/7033/2962/8503/10524/8243/4602/9682/2786/208/3326/23030/6908/1956/5536/3169/858/5432/3480/10728/5595/7528/3727/27161/2354/596/5440/8841/685/54331/347/2309/9687/59345/8204/5430/207/5451/2625/57690/1027/51764/94235/5441/10735/6720/192670/2100/1950/9611/55970/2874/2194/4314/346562/2289/7391/5163/5437/2793/3320/1382/2033/4846/9126/3065/2002/2066/861/23028/6256/23112/10498/1385/1738/5296/808/6258/3276/5916/8202/8648/2288/2790 183 Human_papillomavirus_type_16 R-HSA-400253 Circadian Clock 56/4644 70/10654 4.429896460873665e-10 1.8948611995749245e-9 6.710241108897209e-10 8454/79718/5936/3091/5469/1387/150094/6907/5499/10499/23054/1386/23411/85441/7314/5054/8945/10135/1454/5465/64784/4208/6604/6233/8864/1453/5500/26224/10743/1374/4783/406/4209/5501/8553/2908/1390/7311/23373/8841/8204/4862/6500/200186/1408/6720/7316/9611/2033/79365/6256/10498/1385/8648/551/10891 56 Human_papillomavirus_type_16 R-HSA-5654743 Signaling by FGFR4 37/4644 41/10654 4.723449706677078e-10 2.0142856955829605e-9 7.133157131823967e-10 5295/4893/5335/9965/2264/2885/5518/2253/3845/3265/7314/5515/5290/8823/5594/2249/6714/2247/6233/2246/2251/5781/6464/673/6654/7311/2549/5595/5516/8822/10253/8817/2254/7316/26281/10818/867 37 Human_papillomavirus_type_16 R-HSA-159227 Transport of the SLBP independent Mature mRNA 32/4644 34/10654 5.109078120314048e-10 2.1525635443845675e-9 7.622838225978287e-10 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10482/8086/22916/81929/9631/79023/23636/4686/53371/9688/10189/8480 32 Human_papillomavirus_type_16 R-HSA-165054 Rev-mediated nuclear export of HIV RNA 32/4644 34/10654 5.109078120314048e-10 2.1525635443845675e-9 7.622838225978287e-10 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/5902/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/1104/5905/81929/9631/79023/23636/53371/9688/8480 32 Human_papillomavirus_type_16 R-HSA-4085377 SUMOylation of SUMOylation proteins 32/4644 34/10654 5.109078120314048e-10 2.1525635443845675e-9 7.622838225978287e-10 23165/348995/6613/57122/23511/23279/23225/9972/8021/55746/51588/10762/79902/9883/6396/129401/4928/5903/55706/7175/10210/4927/8086/7329/81929/9631/79023/23636/53371/9688/7341/8480 32 Human_papillomavirus_type_16 R-HSA-5654727 Negative regulation of FGFR2 signaling 32/4644 34/10654 5.109078120314048e-10 2.1525635443845675e-9 7.622838225978287e-10 2250/2885/5518/2252/2253/7314/5515/8823/5594/2249/6714/2248/2247/6233/2246/2251/5781/673/2263/7311/5595/5516/8822/10253/8817/2254/7316/26281/10818/867/2255/27006 32 Human_papillomavirus_type_16 R-HSA-429914 Deadenylation-dependent mRNA decay 47/4644 56/10654 5.214494171120605e-10 2.1903997970306012e-9 7.756827131323434e-10 5393/80153/23404/26986/28960/25904/1973/10767/55571/11340/57472/85456/29883/80349/51690/11157/1981/1977/23016/118460/9924/23644/5073/27258/4850/9652/57819/246175/4848/23019/23658/1975/51010/56915/1974/167227/22894/1656/27257/4849/25804/9337/51013/9775/54464/6499/54512 47 Human_papillomavirus_type_16 R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 29/4644 30/10654 5.7698970253013e-10 2.416467321342604e-9 8.557396373738299e-10 7124/7375/10616/1540/3551/7314/257397/81858/8737/55072/23118/8517/7128/10454/6233/331/8717/330/27005/7311/1147/7186/56957/6885/7316/7132/329/9099/7185 29 Human_papillomavirus_type_16 R-HSA-9020591 Interleukin-12 signaling 41/4644 47/10654 5.874662121818248e-10 2.4530211181282746e-9 8.686843739029491e-10 3593/5908/1265/3313/6175/3717/3181/4001/3594/4282/5062/1072/3592/6627/9049/27250/9987/3185/3458/5478/302/552900/7297/6775/3595/4478/998/6648/3716/2939/6888/3586/829/5055/6647/6950/4507/6845/375/5721/5034 41 Human_papillomavirus_type_16 R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 57/4644 72/10654 6.583500921990952e-10 2.7408462295410406e-9 9.7061141189434e-10 8773/55763/5563/71/7531/51807/10971/7533/2810/53632/10381/60412/7846/81027/23433/5879/79861/51422/4644/7534/6810/4641/10376/11336/6844/9882/801/4218/805/84617/7532/10382/7277/5571/347733/208/5867/4012/10383/60/84790/5564/5565/7280/7529/55770/23265/6517/10890/10640/4627/207/8766/149371/9847/808/54536 57 Human_papillomavirus_type_16 R-HSA-5619084 ABC transporter disorders 60/4644 77/10654 7.446330505084167e-10 3.090888076518665e-9 1.0945711611335181e-9 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/5696/5691/7314/5718/5700/122706/5707/10956/79139/91445/23198/9861/5698/215/5692/5713/5710/5719/6233/10058/6048/5706/19/335/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 60 Human_papillomavirus_type_16 R-HSA-6806003 Regulation of TP53 Expression and Degradation 34/4644 37/10654 7.70212039078721e-10 3.187632716305149e-9 1.1288311828758154e-9 11200/472/639/4194/8900/2475/5518/51230/7314/5515/6446/117584/890/983/5519/10000/900/7157/6233/7874/5170/1029/80196/1616/208/79109/7311/5516/1017/207/7316/9099/5527/4193 34 Human_papillomavirus_type_16 R-HSA-8868773 rRNA processing in the nucleus and cytosol 127/4644 195/10654 8.124068441463138e-10 3.352372948050819e-9 1.1871703728701554e-9 6158/5393/6138/6227/6206/6234/6191/6128/6132/6129/23404/55226/6176/10528/84135/27340/27043/6224/6146/6154/6202/51096/6169/55272/6175/6218/5394/6173/6167/23481/6156/117246/6143/6139/26168/11340/3921/10607/6208/6170/10813/6203/54433/6147/27292/6222/1454/56902/6134/6155/6231/6142/23521/6207/10969/6233/6188/1453/4691/23016/118460/6122/6230/2091/55651/6194/6166/6136/6125/4839/6232/6160/65083/6193/10200/6210/6229/6205/140801/6235/6181/705/7311/6223/25873/55505/51010/26354/56915/51202/9045/6187/6168/6157/6137/22894/6144/9349/4736/57418/22803/51121/6159/25879/6217/81887/6152/51065/6141/55781/6164/6209/11224/6130/6204/1736/6228/51013/6124/83732/6189/6135/6201/6161/54512/6133/9188 127 Human_papillomavirus_type_16 R-HSA-72187 mRNA 3'-end processing 48/4644 58/10654 8.95119427760321e-10 3.6828520737470098e-9 1.3042024074791527e-9 8683/6431/51585/199746/81608/1477/65109/9877/53981/7919/6432/6430/11051/8106/22794/9785/11338/4116/1478/10250/51362/23283/10914/84324/6428/10212/55110/6429/10898/10569/9295/51692/9939/6426/22916/1479/10921/79869/29894/4686/8189/10978/7307/9984/10189/9775/6427/55339 48 Human_papillomavirus_type_16 R-HSA-1643713 Signaling by EGFR in Cancer 25/4644 25/10654 9.302972533290792e-10 3.794206530292727e-9 1.3436361798388169e-9 5295/374/4893/5335/7039/2885/3845/3265/7314/1839/5290/2069/6233/255324/6464/6654/7311/1956/2549/11140/685/7316/1950/867/3320 25 Human_papillomavirus_type_16 R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 25/4644 25/10654 9.302972533290792e-10 3.794206530292727e-9 1.3436361798388169e-9 11065/7321/8697/51529/29945/51434/9184/29882/7314/996/51433/119504/7324/64682/6233/246184/8881/10393/7311/25906/991/7316/4085/4751/701 25 Human_papillomavirus_type_16 R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 25/4644 25/10654 9.302972533290792e-10 3.794206530292727e-9 1.3436361798388169e-9 5982/6117/10714/7314/6118/3978/5985/5984/6233/5424/7515/54107/5425/5111/6119/5427/51426/7311/3980/5983/56655/57804/7316/5426/5981 25 Human_papillomavirus_type_16 R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 92/4644 132/10654 9.816437739059133e-10 3.990379137418678e-9 1.4131064657400429e-9 83990/151987/5892/9156/1763/7486/5982/472/6613/80198/4683/165918/84126/8900/8924/2067/672/6117/7334/10714/348654/83695/7314/6118/25/5888/51588/51720/63967/5531/116028/890/197342/7517/9656/84464/5985/5984/6233/7158/6047/5884/5810/5424/80010/7516/54107/580/11073/5425/641/5111/6119/3364/10524/5427/144715/5889/5429/1111/7329/79728/51426/146956/7311/5983/56655/51750/1017/54962/5893/5883/10111/57804/675/51548/545/7336/2072/29086/7316/5426/10635/7341/8914/23514/5932/9025/79184/7156/5890/5981 92 Human_papillomavirus_type_16 R-HSA-5654741 Signaling by FGFR3 36/4644 40/10654 9.84084947645661e-10 3.990379137418678e-9 1.4131064657400429e-9 5295/4893/2250/5335/2885/5518/2253/3845/3265/7314/5515/5290/8823/5594/2249/6714/2247/6233/2246/5781/6464/673/6654/7311/2549/5595/5516/8822/10253/8817/2254/7316/26281/10818/2261/867 36 Human_papillomavirus_type_16 R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 31/4644 33/10654 1.1087393048438965e-9 4.452553524039061e-9 1.5767755286389592e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/3303/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/3304/81929/9631/79023/23636/53371/9688/8480 31 Human_papillomavirus_type_16 R-HSA-180746 Nuclear import of Rev protein 31/4644 33/10654 1.1087393048438965e-9 4.452553524039061e-9 1.5767755286389592e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/1104/3837/81929/9631/79023/23636/53371/9688/8480 31 Human_papillomavirus_type_16 R-HSA-2559585 Oncogene Induced Senescence 31/4644 33/10654 1.1087393048438965e-9 4.452553524039061e-9 1.5767755286389592e-9 27327/5925/2114/1869/4194/1031/192669/1032/1030/4343/7314/7027/5594/6667/7157/6233/7029/26523/1019/1029/1870/7311/2113/5595/57690/192670/7316/1871/1021/23112/4193 31 Human_papillomavirus_type_16 R-HSA-72165 mRNA Splicing - Minor Pathway 44/4644 52/10654 1.1107581848992666e-9 4.452553524039061e-9 1.5767755286389592e-9 6633/6431/4904/51639/23450/5431/5435/5433/9416/23020/5439/9410/10907/10262/6432/83443/5438/9343/6636/2963/6635/5434/6632/24148/5436/6637/57819/2962/6426/5432/22916/23451/5440/55599/5430/11325/5441/10594/4686/5437/6634/6427/10992/6628 44 Human_papillomavirus_type_16 R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 38/4644 43/10654 1.1239895763805833e-9 4.4927560560169756e-9 1.5910123858198692e-9 2788/107/554/2782/2787/5567/10681/112/5573/111/2792/2785/2783/2784/196883/115/2791/5568/359/113/5566/2786/5577/109/54331/5575/59345/51764/94235/114/108/8766/55970/2778/2793/5576/551/2790 38 Human_papillomavirus_type_16 R-HSA-8863795 Downregulation of ERBB2 signaling 28/4644 29/10654 1.2849433022485333e-9 5.12152117345083e-9 1.8136759529345327e-9 26469/2064/145957/4145/9542/7314/1839/2065/2069/9101/10000/6233/5782/10193/3084/208/10718/7311/1956/11140/8065/685/10273/207/7316/1950/3320/2066 28 Human_papillomavirus_type_16 R-HSA-111933 Calmodulin induced events 33/4644 36/10654 1.6330368106063602e-9 6.435816419327875e-9 2.2791051880727443e-9 817/5578/5582/107/814/818/5567/112/5573/111/5613/5580/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5575/114/108/5576/1385/808/5137 33 Human_papillomavirus_type_16 R-HSA-111997 CaM pathway 33/4644 36/10654 1.6330368106063602e-9 6.435816419327875e-9 2.2791051880727443e-9 817/5578/5582/107/814/818/5567/112/5573/111/5613/5580/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5575/114/108/5576/1385/808/5137 33 Human_papillomavirus_type_16 R-HSA-168638 NOD1/2 Signaling Pathway 33/4644 36/10654 1.6330368106063602e-9 6.435816419327875e-9 2.2791051880727443e-9 834/1432/5603/83737/3654/7334/1540/3551/7314/257397/8767/23118/841/8517/7128/837/10454/6233/5600/6300/5608/330/64127/3656/7189/7311/1147/6885/842/10392/835/7316/329 33 Human_papillomavirus_type_16 R-HSA-6804757 Regulation of TP53 Degradation 33/4644 36/10654 1.6330368106063602e-9 6.435816419327875e-9 2.2791051880727443e-9 11200/472/4194/8900/2475/5518/51230/7314/5515/6446/117584/890/983/5519/10000/900/7157/6233/7874/5170/1029/80196/1616/208/79109/7311/5516/1017/207/7316/9099/5527/4193 33 Human_papillomavirus_type_16 R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 35/4644 39/10654 2.0447157361203095e-9 8.035675568002224e-9 2.8456607030776538e-9 5982/25898/6117/10714/55666/7314/6118/9636/11201/51455/5985/5984/6233/5424/124739/54107/7706/5425/5111/6119/5427/5429/9246/51426/7311/5983/56655/57804/7316/5426/9100/10459/7415/5981/5980 35 Human_papillomavirus_type_16 R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 24/4644 24/10654 2.1404891348242633e-9 8.388564961336429e-9 2.9706288492709567e-9 2237/1763/5982/5422/6117/10714/5558/6118/3978/5557/5985/5984/23649/5424/54107/5425/5111/6119/5427/5983/56655/57804/5426/5981 24 Human_papillomavirus_type_16 R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 37/4644 42/10654 2.2942993732021887e-9 8.916626095852273e-9 3.157630278907809e-9 9070/5929/6657/324/6932/90780/25776/6659/7314/51176/8945/6662/7534/7091/83439/6233/7514/7089/331/6658/4221/7090/283149/6934/607/7088/208/57680/7311/55553/1487/1499/207/8085/7316/3065/26108 37 Human_papillomavirus_type_16 R-HSA-3928662 EPHB-mediated forward signaling 37/4644 42/10654 2.2942993732021887e-9 8.916626095852273e-9 3.157630278907809e-9 71/2051/10094/2047/2534/9475/8976/6093/8997/3265/5879/1072/10093/5921/6453/2902/6714/7525/10109/2904/5747/7074/1949/10092/4067/998/2048/10097/387/60/5058/3984/3985/6383/10552/10096/10095 37 Human_papillomavirus_type_16 R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 37/4644 42/10654 2.2942993732021887e-9 8.916626095852273e-9 3.157630278907809e-9 2788/6000/2780/1459/2770/1460/10576/1457/2782/10574/10693/2773/2787/10575/10681/8786/2792/2785/2783/2784/2771/2791/2786/22948/9628/10694/54331/59345/51764/94235/7203/908/55970/346562/2793/6950/2790 37 Human_papillomavirus_type_16 R-HSA-112399 IRS-mediated signalling 41/4644 48/10654 2.326500888281033e-9 8.991957978672973e-9 3.1843074358957448e-9 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/54106/5290/3667/8823/57761/2260/2249/2248/2247/2246/2251/5781/5170/2322/2263/208/6654/2549/8822/8817/2254/5289/26281/10818/2261/2255/27006/5296 41 Human_papillomavirus_type_16 R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 41/4644 48/10654 2.326500888281033e-9 8.991957978672973e-9 3.1843074358957448e-9 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/8812/905/2071/5432/22916/6917/5440/902/5430/6749/5441/7469/4686/9150/5437/6827/2968/1022/8178 41 Human_papillomavirus_type_16 R-HSA-392518 Signal amplification 30/4644 32/10654 2.4014887553962907e-9 9.180623225670288e-9 3.2511191525800925e-9 2788/64805/2770/2769/1432/2782/2773/2787/10681/2792/6714/2785/2783/2784/2771/2791/6915/2786/5321/54331/59345/51764/94235/55970/2767/346562/2793/9630/2790/10672 30 Human_papillomavirus_type_16 R-HSA-451326 Activation of kainate receptors upon glutamate binding 30/4644 32/10654 2.4014887553962907e-9 9.180623225670288e-9 3.2511191525800925e-9 2788/5331/2900/2898/2782/1741/1739/2897/2787/10681/2901/2792/2785/2783/2784/83988/801/2791/805/2899/2786/54331/59345/51764/94235/55970/2793/1742/808/2790 30 Human_papillomavirus_type_16 R-HSA-5656169 Termination of translesion DNA synthesis 30/4644 32/10654 2.4014887553962907e-9 9.180623225670288e-9 3.2511191525800925e-9 5982/6117/10714/7314/6118/9636/11201/51455/5985/5984/6233/5424/124739/54107/7706/5425/5111/6119/5427/5429/9246/51426/7311/5983/56655/57804/7316/5426/9100/5981 30 Human_papillomavirus_type_16 R-HSA-73863 RNA Polymerase I Transcription Termination 30/4644 32/10654 2.4014887553962907e-9 9.180623225670288e-9 3.2511191525800925e-9 5435/2965/64425/2967/30834/404672/2068/9533/5434/9015/79101/221830/7270/4331/9013/2966/2071/10849/6908/5440/902/9014/25885/5441/51082/7343/5437/2968/84172/1022 30 Human_papillomavirus_type_16 R-HSA-9006936 Signaling by TGF-beta family members 74/4644 102/10654 2.5318025008548253e-9 9.652497034509021e-9 3.4182230560740207e-9 892/7321/4738/130399/8239/9612/4609/4089/22938/23327/4088/5499/1030/7040/904/7314/5054/7027/6497/51592/50848/7323/91/93/6667/4092/11171/7050/7046/94/5494/9958/9040/6233/7514/1025/7029/57530/5500/4090/4221/5590/9765/269/3726/5501/1024/60436/8812/1874/142/905/4087/7048/7311/387/57154/51377/10273/50855/4086/64750/659/54778/7316/1875/9611/5933/867/3065/6498/657/56288/25937 74 Human_papillomavirus_type_16 R-HSA-75067 Processing of Capped Intronless Pre-mRNA 27/4644 28/10654 2.857962025529262e-9 1.0866451820643779e-8 3.8481188876046545e-9 51585/81608/1477/53981/134353/11051/8106/1478/23283/6636/10914/6635/7884/84967/6637/10898/51692/22916/1479/79869/29894/4686/8189/10978/6634/55339/6628 27 Human_papillomavirus_type_16 R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 120/4644 185/10654 3.4241241583191896e-9 1.2983908632761684e-8 4.597970420274986e-9 6158/5393/6138/6227/6206/6234/6191/6128/6132/6129/23404/6176/10528/84135/27340/27043/6224/6146/6154/6202/51096/6169/55272/6175/6218/5394/6173/6167/23481/6156/117246/6143/6139/26168/11340/3921/10607/6208/6170/10813/6203/6147/6222/1454/56902/6134/6155/6231/6142/23521/6207/10969/6233/6188/1453/4691/23016/118460/6122/6230/2091/6194/6166/6136/6125/6232/6160/65083/6193/10200/6210/6229/6205/140801/6235/6181/705/7311/6223/25873/51010/26354/56915/51202/9045/6187/6168/6157/6137/22894/6144/9349/4736/57418/22803/51121/6159/25879/6217/81887/6152/51065/6141/55781/6164/6209/11224/6130/6204/6228/51013/6124/83732/6189/6135/6201/6161/54512/6133/9188 120 Human_papillomavirus_type_16 R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 32/4644 35/10654 3.4539425576590747e-9 1.3026562925794844e-8 4.613075515605783e-9 23165/91754/348995/57122/23511/23279/23225/9972/8021/55746/10762/983/79902/9883/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/81929/9631/140609/79023/23636/53371/9688/8480 32 Human_papillomavirus_type_16 R-HSA-8953750 Transcriptional Regulation by E2F6 32/4644 35/10654 3.4539425576590747e-9 1.3026562925794844e-8 4.613075515605783e-9 6045/80012/79813/11335/1869/1911/5928/10138/23512/672/6241/5888/83746/7027/2146/1876/7029/8726/7703/317/23429/6015/84108/5931/1111/648/23468/23269/8317/4149/5932/10919 32 Human_papillomavirus_type_16 R-HSA-112382 Formation of RNA Pol II elongation complex 49/4644 61/10654 4.292598672201693e-9 1.6060042498930603e-8 5.6873166969240685e-9 5431/5435/5433/2965/5439/2967/11198/904/51497/4300/80349/404672/5438/2068/1025/23168/7936/6829/123169/25920/2963/5434/5436/79577/4331/2966/2962/4298/8812/905/2071/5432/22916/55840/6917/5440/902/6830/5430/6749/5441/7469/4686/9150/5437/6827/2968/1022/8178 49 Human_papillomavirus_type_16 R-HSA-75955 RNA Polymerase II Transcription Elongation 49/4644 61/10654 4.292598672201693e-9 1.6060042498930603e-8 5.6873166969240685e-9 5431/5435/5433/2965/5439/2967/11198/904/51497/4300/80349/404672/5438/2068/1025/23168/7936/6829/123169/25920/2963/5434/5436/79577/4331/2966/2962/4298/8812/905/2071/5432/22916/55840/6917/5440/902/6830/5430/6749/5441/7469/4686/9150/5437/6827/2968/1022/8178 49 Human_papillomavirus_type_16 R-HSA-8943724 Regulation of PTEN gene transcription 49/4644 61/10654 4.292598672201693e-9 1.6060042498930603e-8 5.6873166969240685e-9 1912/3725/6591/1822/9112/6045/80012/1911/5928/23512/57332/1107/2475/1386/23186/2146/51564/5594/84232/7101/84733/57459/3066/7157/8726/57521/6015/9219/8535/5931/1108/2122/10014/54815/6009/57504/648/23466/53615/5595/8841/5468/5978/57167/1958/6615/3065/23028/10542 49 Human_papillomavirus_type_16 R-HSA-195721 Signaling by WNT 196/4644 331/10654 4.755845229877006e-9 1.7745879940205956e-8 6.284319564675103e-9 2788/8454/27123/9070/5689/2780/857/5579/5682/5331/1459/5526/1452/5578/1212/5929/5582/27327/1460/55737/143471/5705/6657/8452/5530/55366/5709/9978/5695/1457/4609/5881/5711/1387/5683/324/5699/8312/2782/5702/192669/1855/6932/90780/163/5518/4343/5593/25776/3845/6659/5696/5691/4920/7314/5879/5515/2787/5718/51176/8945/7476/161/6662/51701/5700/122706/5707/1856/1454/8322/23198/10681/9101/7471/7534/5528/7091/83439/2792/9861/5519/2932/5698/5880/5692/5713/2785/2783/23002/2784/5710/5719/6233/7474/1857/7514/1213/1211/7089/331/8607/1175/26523/801/6658/2791/4221/805/123169/1173/144165/7090/6597/864/4772/409/79577/283149/5706/160/8658/5714/6934/10524/5688/5687/607/5708/51339/5529/7088/2786/208/57680/5704/7311/387/5694/55553/5516/57154/27161/815/5684/8295/5720/54331/7015/6885/1487/1499/5525/59345/207/8085/5690/5532/57690/5717/9491/50855/6500/51764/94235/10197/192670/64750/7316/10213/55970/5216/5715/5701/2793/1455/5685/5686/2033/54894/5534/3065/23112/23513/5527/1488/5716/23072/26108/808/9736/5693/5721/6259/2790/5592 196 Human_papillomavirus_type_16 R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 23/4644 23/10654 4.924375674597867e-9 1.8229285148973106e-8 6.455507064047197e-9 5431/5435/5433/5439/51497/5438/7936/6829/25920/2963/5434/5436/2962/5432/22916/5440/5430/5441/7469/4686/9150/5437/6827 23 Human_papillomavirus_type_16 R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 23/4644 23/10654 4.924375674597867e-9 1.8229285148973106e-8 6.455507064047197e-9 11065/7321/8697/51529/29945/51434/29882/7314/996/983/51433/119504/7324/64682/6233/246184/8881/891/10393/7311/25906/991/7316 23 Human_papillomavirus_type_16 R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 23/4644 23/10654 4.924375674597867e-9 1.8229285148973106e-8 6.455507064047197e-9 7321/8239/9612/4089/23327/4088/7314/6497/51592/7323/7050/5494/6233/60436/142/4087/7311/64750/54778/7316/9611/3065/6498 23 Human_papillomavirus_type_16 R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 29/4644 31/10654 5.1909493452731926e-9 1.90154097426065e-8 6.733896086213954e-9 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/3837/81929/9631/79023/23636/53371/9688/8480 29 Human_papillomavirus_type_16 R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 29/4644 31/10654 5.1909493452731926e-9 1.90154097426065e-8 6.733896086213954e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/81929/9631/79023/23636/53371/9688/8480 29 Human_papillomavirus_type_16 R-HSA-399719 Trafficking of AMPA receptors 29/4644 31/10654 5.1909493452731926e-9 1.90154097426065e-8 6.733896086213954e-9 5579/23426/817/5578/5582/9463/9495/1739/163/10368/818/161/4646/2892/1175/2891/1173/59283/2890/2036/160/816/10369/2893/815/4905/27092/1742/4193 29 Human_papillomavirus_type_16 R-HSA-399721 Glutamate binding, activation of AMPA receptors and synaptic plasticity 29/4644 31/10654 5.1909493452731926e-9 1.90154097426065e-8 6.733896086213954e-9 5579/23426/817/5578/5582/9463/9495/1739/163/10368/818/161/4646/2892/1175/2891/1173/59283/2890/2036/160/816/10369/2893/815/4905/27092/1742/4193 29 Human_papillomavirus_type_16 R-HSA-72312 rRNA processing 130/4644 205/10654 6.4356009048294955e-9 2.3513406430926517e-8 8.32676432861711e-9 6158/5393/6138/6227/6206/6234/6191/6128/6132/6129/23404/55226/6176/10528/84135/27340/27043/6224/6146/6154/6202/51096/6169/55272/6175/6218/5394/6173/6167/23481/6156/117246/6143/6139/26168/11340/3921/10607/6208/6170/10813/60528/6203/54433/6147/27292/6222/1454/56902/6134/6155/6231/6142/23521/6207/10969/6233/6188/1453/4691/23016/118460/6122/6230/2091/55651/6194/6166/3028/6136/6125/4839/6232/6160/65083/6193/10200/6210/6229/6205/140801/6235/6181/705/7311/6223/25873/55505/51010/26354/56915/51202/9045/6187/6168/6157/6137/22894/6144/9349/4736/57418/22803/51121/6159/25879/6217/81887/6152/51065/6141/55781/6164/54931/6209/11224/6130/6204/1736/6228/51013/6124/83732/6189/6135/6201/6161/54512/6133/9188 130 Human_papillomavirus_type_16 R-HSA-5693537 Resolution of D-Loop Structures 31/4644 34/10654 7.286331397239685e-9 2.6552527143707217e-8 9.40300319753146e-9 83990/5892/9156/1763/7486/472/80198/4683/672/348654/5888/116028/197342/7517/84464/80010/7516/580/641/10524/5889/79728/146956/51750/10111/675/10635/23514/5932/7156/5890 31 Human_papillomavirus_type_16 R-HSA-1980143 Signaling by NOTCH1 56/4644 73/10654 7.737197830447698e-9 2.8122509212741244e-8 9.958978390977132e-9 8454/79718/892/182/3091/23385/9978/9759/9612/4609/22938/1387/6907/408/83737/6868/9794/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/7091/8650/102/8850/3066/6233/7089/5663/7090/142678/23220/409/10046/1024/10014/7088/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 56 Human_papillomavirus_type_16 R-HSA-5689603 UCH proteinases 73/4644 102/10654 8.61973147094826e-9 3.124931073317935e-8 1.1066267521522042e-8 5689/221937/5682/4738/10445/143471/5705/5709/5695/11047/5711/7347/5683/5699/5702/7040/7345/3054/5696/5691/7314/5718/3607/5700/122706/5707/83444/171023/23198/86/4092/9861/7046/5698/5692/5713/5710/8473/9958/5719/6233/93973/8607/5706/580/5714/5688/5687/5708/5704/7048/7311/60/5694/7528/5684/5720/51377/5690/5717/9491/10197/7316/10213/8314/5715/5701/4798/5685/5686/5716/5693/5721 73 Human_papillomavirus_type_16 R-HSA-167169 HIV Transcription Elongation 39/4644 46/10654 9.038913880398503e-9 3.2516913267177175e-8 1.151516154263993e-8 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/7469/4686/9150/5437/6827/2968/1022/8178 39 Human_papillomavirus_type_16 R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 39/4644 46/10654 9.038913880398503e-9 3.2516913267177175e-8 1.151516154263993e-8 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/7469/4686/9150/5437/6827/2968/1022/8178 39 Human_papillomavirus_type_16 R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 39/4644 46/10654 9.038913880398503e-9 3.2516913267177175e-8 1.151516154263993e-8 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/7469/4686/9150/5437/6827/2968/1022/8178 39 Human_papillomavirus_type_16 R-HSA-5654696 Downstream signaling of activated FGFR2 28/4644 30/10654 1.1196293698306213e-8 4.0174936211569355e-8 1.4227084737112755e-8 5295/4893/2250/5335/2885/2252/2253/3845/3265/5290/8823/2249/2248/2247/2246/2251/5781/6464/2263/6654/2549/8822/8817/2254/26281/10818/2255/27006 28 Human_papillomavirus_type_16 R-HSA-113510 E2F mediated regulation of DNA replication 22/4644 22/10654 1.1327555640918356e-8 4.033644813250877e-8 1.428428069065847e-8 5925/5422/1869/84515/4998/28227/5518/5001/5558/5515/23594/7027/5557/983/5519/7029/23649/4999/5000/891/23595/5516 22 Human_papillomavirus_type_16 R-HSA-1250196 SHC1 events in ERBB2 signaling 22/4644 22/10654 1.1327555640918356e-8 4.033644813250877e-8 1.428428069065847e-8 4893/5578/2064/145957/9542/2885/3845/3265/1839/2065/2069/5580/6464/5782/3084/6654/10718/1956/685/1950/2066/5581 22 Human_papillomavirus_type_16 R-HSA-392170 ADP signalling through P2Y purinoceptor 12 22/4644 22/10654 1.1327555640918356e-8 4.033644813250877e-8 1.428428069065847e-8 2788/64805/2770/2782/2773/2787/10681/2792/2785/2783/2784/2771/2791/2786/54331/59345/51764/94235/55970/346562/2793/2790 22 Human_papillomavirus_type_16 R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 25/4644 26/10654 1.408084408865642e-8 5.0013732294645454e-8 1.77112815718743e-8 83990/5892/9156/1763/7486/472/4683/672/5888/116028/7517/80010/7516/580/641/10524/5889/79728/51750/10111/675/10635/5932/7156/5890 25 Human_papillomavirus_type_16 R-HSA-351202 Metabolism of polyamines 47/4644 59/10654 1.4787364334088072e-8 5.23905862644585e-8 1.8552992997579933e-8 5689/5682/143471/5705/5709/5695/5711/4946/5683/5699/5702/5696/5691/5718/1728/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6303/5706/5714/5688/5687/5708/5704/5694/5684/5720/5690/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 47 Human_papillomavirus_type_16 R-HSA-180910 Vpr-mediated nuclear import of PICs 30/4644 33/10654 1.5328983260920088e-8 5.403659174640925e-8 1.9135890238440312e-8 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/3159/79023/23636/53371/9688/8815/8480 30 Human_papillomavirus_type_16 R-HSA-5693568 Resolution of D-loop Structures through Holliday Junction Intermediates 30/4644 33/10654 1.5328983260920088e-8 5.403659174640925e-8 1.9135890238440312e-8 83990/5892/9156/1763/7486/472/80198/4683/672/348654/5888/116028/197342/7517/84464/80010/7516/580/641/10524/5889/79728/146956/10111/675/10635/23514/5932/7156/5890 30 Human_papillomavirus_type_16 R-HSA-3899300 SUMOylation of transcription cofactors 38/4644 45/10654 1.77181737255582e-8 6.230224996731368e-8 2.2062994323871447e-8 1912/6045/80012/6613/28996/9612/1911/9994/1387/57332/115426/10499/6612/11315/3622/51588/1655/84733/10155/9063/7703/6015/8554/8535/4869/10210/10521/1616/7329/25942/648/1487/8204/7341/2033/6294/8648/10891 38 Human_papillomavirus_type_16 R-HSA-176033 Interactions of Vpr with host cellular proteins 32/4644 36/10654 1.8021188534080713e-8 6.32093187832881e-8 2.238421312654236e-8 23165/348995/57122/23511/292/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/3159/79023/23636/53371/9688/8815/8480/291 32 Human_papillomavirus_type_16 R-HSA-373760 L1CAM interactions 82/4644 119/10654 1.8328549487761454e-8 6.412706965418783e-8 2.2709214747928617e-8 9252/6711/71/7430/1459/51807/1785/1460/10381/8829/4684/3688/1457/285643/5605/7846/3690/1808/81027/6456/1741/1739/6709/4897/5962/163/6196/1759/6197/8986/3312/100133941/5879/6331/6900/161/79861/5594/6327/284217/55800/2260/3672/8650/6714/10376/6195/214/7410/3685/1213/1211/1175/1173/84617/6712/3674/10382/7277/4478/160/3912/26052/27330/347733/6386/2048/3897/10383/24137/1956/60/84790/5058/7280/5595/5604/10048/11313/1742/287/288 82 Human_papillomavirus_type_16 R-HSA-1489509 DAG and IP3 signaling 36/4644 42/10654 1.8914493233995685e-8 6.601252240620882e-8 2.3376907060607396e-8 5335/817/5578/5582/107/814/818/5567/112/5573/111/5613/5580/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5575/114/108/10768/5576/1385/5581/808/5137 36 Human_papillomavirus_type_16 R-HSA-191859 snRNP Assembly 43/4644 53/10654 2.2193877928275256e-8 7.707428399349056e-8 2.7294190677816368e-8 23165/6633/6606/25929/348995/57122/23511/23279/23225/79084/9972/8021/55746/10762/79902/9883/6636/10419/6396/129401/50628/4928/6635/5903/6632/55706/7175/6637/4927/8086/79833/22916/81929/11218/9631/79023/23636/4686/53371/9688/6634/8480/6628 43 Human_papillomavirus_type_16 R-HSA-194441 Metabolism of non-coding RNA 43/4644 53/10654 2.2193877928275256e-8 7.707428399349056e-8 2.7294190677816368e-8 23165/6633/6606/25929/348995/57122/23511/23279/23225/79084/9972/8021/55746/10762/79902/9883/6636/10419/6396/129401/50628/4928/6635/5903/6632/55706/7175/6637/4927/8086/79833/22916/81929/11218/9631/79023/23636/4686/53371/9688/6634/8480/6628 43 Human_papillomavirus_type_16 R-HSA-5654732 Negative regulation of FGFR3 signaling 27/4644 29/10654 2.4093714789819077e-8 8.325980751260138e-8 2.9484660048728558e-8 2250/2885/5518/2253/7314/5515/8823/5594/2249/6714/2247/6233/2246/5781/673/7311/5595/5516/8822/10253/8817/2254/7316/26281/10818/2261/867 27 Human_papillomavirus_type_16 R-HSA-72086 mRNA Capping 27/4644 29/10654 2.4093714789819077e-8 8.325980751260138e-8 2.9484660048728558e-8 5431/5435/5433/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/4686/5437/2968/1022 27 Human_papillomavirus_type_16 R-HSA-2559583 Cellular Senescence 123/4644 195/10654 2.594801124136164e-8 8.915422699821577e-8 3.1572041222311476e-8 1912/3725/9134/11065/4790/7321/6045/8697/27327/80012/7295/5925/472/79813/3576/2114/1869/1911/26277/4194/1031/5928/1432/4683/23512/57332/192669/8900/51529/4001/29945/8091/51434/1032/1030/6196/4343/6197/29882/4217/54386/3569/7314/996/7014/5601/5606/7027/2146/5594/898/890/5970/9261/6667/51433/5598/84733/119504/6195/7157/7324/64682/6233/2353/7029/8726/5600/26523/5608/6015/1019/9448/246184/1029/8535/5931/7013/1051/50488/8881/6774/7867/3552/10524/5602/10393/1870/51343/7311/25906/57634/648/23466/3456/2113/6416/23523/5595/1017/25913/3159/7290/10111/57690/1027/192670/3490/8550/29855/7316/1026/1871/65057/1021/25842/23135/23112/5609/5599/10919/4193/23043 123 Human_papillomavirus_type_16 R-HSA-111931 PKA-mediated phosphorylation of CREB 21/4644 21/10654 2.6053623000191352e-8 8.915422699821577e-8 3.1572041222311476e-8 107/5567/112/5573/111/5613/196883/115/801/805/5568/113/5566/5577/109/5575/114/108/5576/1385/808 21 Human_papillomavirus_type_16 R-HSA-389513 CTLA4 inhibitory signaling 21/4644 21/10654 2.6053623000191352e-8 8.915422699821577e-8 3.1572041222311476e-8 5526/941/2534/5518/5515/5528/6714/5519/10000/7525/3932/5781/1493/4067/5529/208/5516/5525/207/942/5527 21 Human_papillomavirus_type_16 R-HSA-6807004 Negative regulation of MET activity 21/4644 21/10654 2.6053623000191352e-8 8.915422699821577e-8 3.1572041222311476e-8 5770/3082/6456/30011/2885/7314/8027/2060/9101/9146/6455/6233/4233/5795/5771/7311/26018/7316/867/10254/6457 21 Human_papillomavirus_type_16 R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 46/4644 58/10654 2.727706004955936e-8 9.221618132417297e-8 3.265636612147627e-8 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/102/8850/3066/6233/5663/142678/10046/1024/10014/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 46 Human_papillomavirus_type_16 R-HSA-2644603 Signaling by NOTCH1 in Cancer 46/4644 58/10654 2.727706004955936e-8 9.221618132417297e-8 3.265636612147627e-8 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/102/8850/3066/6233/5663/142678/10046/1024/10014/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 46 Human_papillomavirus_type_16 R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 46/4644 58/10654 2.727706004955936e-8 9.221618132417297e-8 3.265636612147627e-8 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/102/8850/3066/6233/5663/142678/10046/1024/10014/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 46 Human_papillomavirus_type_16 R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 46/4644 58/10654 2.727706004955936e-8 9.221618132417297e-8 3.265636612147627e-8 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/102/8850/3066/6233/5663/142678/10046/1024/10014/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 46 Human_papillomavirus_type_16 R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 46/4644 58/10654 2.727706004955936e-8 9.221618132417297e-8 3.265636612147627e-8 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/6868/9794/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/102/8850/3066/6233/5663/142678/10046/1024/10014/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 46 Human_papillomavirus_type_16 R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 24/4644 25/10654 3.118509429070892e-8 1.0517472906217456e-7 3.72453555293892e-8 51400/5520/8900/28227/5518/7465/5515/993/890/983/5519/7514/2305/9133/891/4331/5347/5516/1017/994/902/9088/995/1022 24 Human_papillomavirus_type_16 R-HSA-381042 PERK regulates gene expression 29/4644 32/10654 3.215573504741674e-8 1.0792941691752556e-7 3.8220868653691006e-8 5393/1965/23404/3576/3309/4801/6347/11340/468/1054/8894/9451/8570/23016/118460/1968/5073/1051/4800/51010/56915/167227/22894/440/4802/1649/51013/467/54512 29 Human_papillomavirus_type_16 R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 29/4644 32/10654 3.215573504741674e-8 1.0792941691752556e-7 3.8220868653691006e-8 2788/2149/2769/408/2768/2782/2787/5594/10681/2792/6714/2785/2783/2784/2151/2791/409/2786/5595/54331/59345/51764/94235/55970/2767/2793/9630/2790/10672 29 Human_papillomavirus_type_16 R-HSA-109704 PI3K Cascade 37/4644 44/10654 3.459574733334018e-8 1.1584208474624407e-7 4.102296882636997e-8 5295/2250/5291/9965/2264/2885/8660/9846/2252/2253/54106/5290/3667/8823/57761/2260/2249/2248/2247/2246/2251/5781/5170/2322/2263/208/2549/8822/8817/2254/5289/26281/10818/2261/2255/27006/5296 37 Human_papillomavirus_type_16 R-HSA-111465 Apoptotic cleavage of cellular proteins 33/4644 38/10654 3.8549661466223106e-8 1.2846834925679578e-7 4.549428731605778e-8 660/836/324/9414/4001/6709/6093/840/2934/63967/841/100506658/7082/5339/28988/10134/999/5588/5580/839/1828/5747/118/1829/8428/1832/4000/51765/1499/329/4137/7431/6304 33 Human_papillomavirus_type_16 R-HSA-5689896 Ovarian tumor domain proteases 33/4644 38/10654 3.8549661466223106e-8 1.2846834925679578e-7 4.549428731605778e-8 7321/324/64135/7187/7314/8737/8767/55611/8517/80124/983/2099/23586/7128/7157/6233/55593/84282/10318/7706/79155/79589/64127/7189/7311/387/56957/10392/57506/7316/7415/5728/78990 33 Human_papillomavirus_type_16 R-HSA-983231 Factors involved in megakaryocyte development and platelet production 108/4644 168/10654 4.2424882311487234e-8 1.4104765375122414e-7 4.9948975931708596e-8 3443/64837/11311/51807/55619/10381/832/285643/3043/10112/3717/7846/81027/11004/10749/2626/4097/7465/81930/5879/3445/25/79861/30846/5868/3797/23348/23186/5567/29127/55605/3444/5573/91768/3796/23414/3451/3448/89953/56992/10376/3066/7157/3439/3835/3833/161882/221037/3452/9493/81704/3660/3446/9732/84617/85440/9585/10019/10382/5568/830/3832/7277/1793/23303/2623/3659/5566/80005/1062/5889/347733/3440/4602/998/7975/5577/10383/24137/60/25942/84790/84643/3456/1020/10362/7280/829/1017/23468/3441/2624/8165/5575/2625/25970/3449/81928/3705/5576/547/3065/23028/55083/3799/51317/5890/10938 108 Human_papillomavirus_type_16 R-HSA-163685 Integration of energy metabolism 75/4644 108/10654 4.418089343315538e-8 1.4653851888112765e-7 5.189344705847788e-8 2788/5563/5331/2740/2770/5578/2769/107/9495/2782/3630/8826/5518/31/2181/6513/5515/2787/5567/51422/10681/112/5573/5528/111/2792/5519/51085/2785/2783/2784/2771/9370/7086/6844/2182/196883/115/2791/5568/2642/150/113/6616/5566/32/6794/2641/6514/2786/5577/6888/5565/109/5516/54331/5575/59345/51764/94235/114/4082/3790/108/55970/2778/2194/2767/10768/152/2793/5576/5906/9630/2790 75 Human_papillomavirus_type_16 R-HSA-6807878 COPI-mediated anterograde transport 71/4644 101/10654 4.588744407465154e-8 1.5183982084135878e-7 5.377078848866814e-8 6811/6711/11014/51807/5861/10381/1780/8655/84516/832/7846/9382/3630/81027/6709/10652/54732/51164/79861/2801/10466/1315/8615/11316/91949/8729/10376/1314/10540/378/26286/26958/140735/84364/22820/84617/11258/6712/1783/10382/93661/55860/830/7277/10671/966/1639/81876/347733/51143/10383/84790/7280/829/1778/25839/63908/1604/1781/10121/2804/57511/10972/381/4905/9276/287/375/64689/288/372 71 Human_papillomavirus_type_16 R-HSA-4086398 Ca2+ pathway 48/4644 62/10654 5.52235611070869e-8 1.823027205488069e-7 6.455856555429107e-8 2788/2780/5331/5578/27327/5530/2782/192669/6932/4343/5593/3845/2787/51176/51701/8322/10681/83439/2792/2785/2783/2784/7474/26523/801/2791/805/4772/6934/2786/27161/815/54331/6885/1499/59345/5532/57690/51764/94235/192670/55970/2793/5534/23112/808/2790/5592 48 Human_papillomavirus_type_16 R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 20/4644 20/10654 5.991657157959234e-8 1.950416471604827e-7 6.906978089038365e-8 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Human_papillomavirus_type_16 R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 20/4644 20/10654 5.991657157959234e-8 1.950416471604827e-7 6.906978089038365e-8 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Human_papillomavirus_type_16 R-HSA-5213460 RIPK1-mediated regulated necrosis 20/4644 20/10654 5.991657157959234e-8 1.950416471604827e-7 6.906978089038365e-8 356/7314/11035/8737/841/8797/6233/8772/331/8717/8743/330/8837/197259/7311/8795/7186/355/7316/329 20 Human_papillomavirus_type_16 R-HSA-5218859 Regulated Necrosis 20/4644 20/10654 5.991657157959234e-8 1.950416471604827e-7 6.906978089038365e-8 356/7314/11035/8737/841/8797/6233/8772/331/8717/8743/330/8837/197259/7311/8795/7186/355/7316/329 20 Human_papillomavirus_type_16 R-HSA-69186 Lagging Strand Synthesis 20/4644 20/10654 5.991657157959234e-8 1.950416471604827e-7 6.906978089038365e-8 2237/1763/5982/5422/6117/10714/5558/6118/3978/5557/5985/5984/23649/5424/5425/5111/6119/5983/57804/5981 20 Human_papillomavirus_type_16 R-HSA-8876384 Listeria monocytogenes entry into host cells 20/4644 20/10654 5.991657157959234e-8 1.950416471604827e-7 6.906978089038365e-8 6456/30011/2885/7314/8027/2060/1500/6714/999/9146/6455/6233/4233/7311/79872/1499/7316/867/10254/6457 20 Human_papillomavirus_type_16 R-HSA-1839124 FGFR1 mutant receptor activation 28/4644 31/10654 6.724617432661466e-8 2.1738797829548473e-7 7.698325074499666e-8 5295/11052/2250/9530/613/6776/11064/2885/9846/2253/7750/8805/5290/2260/2249/399687/2247/2246/2251/6777/1523/9208/6774/6772/11160/8822/2254/26281 28 Human_papillomavirus_type_16 R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 28/4644 31/10654 6.724617432661466e-8 2.1738797829548473e-7 7.698325074499666e-8 3725/9252/1432/6196/5518/1386/6197/51231/5515/5601/1849/5594/5528/9261/5519/5598/4208/6195/2353/5600/5602/5595/5516/1845/4205/2002/1385/5599 28 Human_papillomavirus_type_16 R-HSA-5654733 Negative regulation of FGFR4 signaling 28/4644 31/10654 6.724617432661466e-8 2.1738797829548473e-7 7.698325074499666e-8 9965/2264/2885/5518/2253/7314/5515/8823/5594/2249/6714/2247/6233/2246/2251/5781/673/7311/5595/5516/8822/10253/8817/2254/7316/26281/10818/867 28 Human_papillomavirus_type_16 R-HSA-5675221 Negative regulation of MAPK pathway 34/4644 40/10654 7.394290593878618e-8 2.384871196140621e-7 8.445505530092457e-8 4893/1844/1850/5526/1852/5605/5894/1847/5518/4140/3845/3265/7314/5515/8844/1849/5594/5528/5519/6233/1843/369/11221/673/5529/7311/5536/7529/5595/5516/5604/5525/7316/5527 34 Human_papillomavirus_type_16 R-HSA-187687 Signalling to ERKs 30/4644 34/10654 7.564887223852275e-8 2.4342974254735647e-7 8.620537831140209e-8 4893/5605/1432/5603/2885/3845/3265/1399/5594/9261/6714/4914/5600/6300/6464/673/7867/2889/6654/5900/7529/5595/25759/5604/57498/10818/53358/4803/1398/5906 30 Human_papillomavirus_type_16 R-HSA-432722 Golgi Associated Vesicle Biogenesis 44/4644 56/10654 9.160656132733387e-8 2.941052758403877e-7 1.0415102239311476e-7 27131/162/1176/5286/1174/1785/8546/7037/3482/408/6456/7164/3312/1362/25977/10618/6643/10053/8301/2495/152503/6844/1213/2580/1211/8907/9685/9026/9829/8905/51429/64746/8673/164/6272/2804/2647/7163/9698/5878/81567/6845/375/4952 44 Human_papillomavirus_type_16 R-HSA-164952 The role of Nef in HIV-1 replication and disease pathogenesis 25/4644 27/10654 1.1073884814730045e-7 3.523052243779196e-7 1.2476127539211318e-7 162/1174/567/2534/163/55690/5062/5879/51606/161/10053/926/3932/1175/8907/940/1173/160/920/8905/164/919/3055/9844/375 25 Human_papillomavirus_type_16 R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 25/4644 27/10654 1.1073884814730045e-7 3.523052243779196e-7 1.2476127539211318e-7 5431/5435/5433/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/5440/902/5430/5441/5437/2968/1022 25 Human_papillomavirus_type_16 R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 25/4644 27/10654 1.1073884814730045e-7 3.523052243779196e-7 1.2476127539211318e-7 5431/5435/5433/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/5440/902/5430/5441/5437/2968/1022 25 Human_papillomavirus_type_16 R-HSA-912526 Interleukin receptor SHC signaling 25/4644 27/10654 1.1073884814730045e-7 3.523052243779196e-7 1.2476127539211318e-7 5295/5777/1437/5291/3558/3717/3563/2885/9846/5290/3718/3567/3562/6464/1438/8503/3636/6654/3716/5293/3561/3568/3560/5296/3559 25 Human_papillomavirus_type_16 R-HSA-157118 Signaling by NOTCH 142/4644 235/10654 1.1568897315138224e-7 3.672208808402472e-7 1.30043332525488e-7 8454/5689/3725/79718/5682/892/4904/182/27327/3091/23385/5705/5709/9978/1869/5695/9759/9612/4609/11060/22938/5711/1387/4088/6907/5683/408/5699/6400/4853/5702/192669/83737/6868/9794/4343/9787/5696/5691/7314/5718/23286/79885/2648/9734/7027/55869/5700/5707/51564/55534/3280/84441/10013/7534/83933/4854/7091/8650/102/10320/9861/8850/5087/5698/5692/5713/595/5710/3002/3066/7157/5719/6233/2324/7029/7089/26523/5663/1999/4192/7090/142678/23220/409/5706/10460/10046/1024/5714/6772/10014/489/5688/5687/5708/59/4855/7088/5704/23493/7311/1956/5694/4851/27161/5684/8841/2208/5720/5584/23462/207/5690/57690/5717/9491/6500/51548/10197/192670/488/7316/10213/1950/9611/1871/5715/5701/5685/5686/2033/55294/3065/861/2683/23112/5716/1385/3516/5693/5721 142 Human_papillomavirus_type_16 R-HSA-1236394 Signaling by ERBB4 45/4644 58/10654 1.290998229721372e-7 4.0886467636548195e-7 1.4479058201936265e-7 5295/4893/2670/51741/23385/6776/4734/10413/145957/83737/6868/9542/2885/3845/3265/7314/6387/1839/5290/2065/2069/23118/348/11059/6714/2099/1447/2567/3925/6233/5663/6464/5241/3084/6654/10718/7311/1956/685/7316/1950/9611/2066/6285/1742 45 Human_papillomavirus_type_16 R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 19/4644 19/10654 1.3777572729707358e-7 4.276534190216687e-7 1.5144420885938224e-7 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Human_papillomavirus_type_16 R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 19/4644 19/10654 1.3777572729707358e-7 4.276534190216687e-7 1.5144420885938224e-7 1869/4609/5928/990/7027/7153/5934/993/7029/286826/5111/91750/1874/55957/4149/1875/5933/3065/132660 19 Human_papillomavirus_type_16 R-HSA-163615 PKA activation 19/4644 19/10654 1.3777572729707358e-7 4.276534190216687e-7 1.5144420885938224e-7 107/5567/112/5573/111/196883/115/801/805/5568/113/5566/5577/109/5575/114/108/5576/808 19 Human_papillomavirus_type_16 R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 19/4644 19/10654 1.3777572729707358e-7 4.276534190216687e-7 1.5144420885938224e-7 11065/7321/8697/51529/29945/51434/29882/996/51433/119504/7324/64682/246184/8881/10393/51343/25906/991/8556 19 Human_papillomavirus_type_16 R-HSA-176412 Phosphorylation of the APC/C 19/4644 19/10654 1.3777572729707358e-7 4.276534190216687e-7 1.5144420885938224e-7 11065/7321/8697/51529/29945/51434/29882/996/983/51433/119504/7324/64682/246184/8881/891/10393/25906/5347 19 Human_papillomavirus_type_16 R-HSA-392851 Prostacyclin signalling through prostacyclin receptor 19/4644 19/10654 1.3777572729707358e-7 4.276534190216687e-7 1.5144420885938224e-7 2788/2782/2787/10681/2792/2785/2783/2784/2791/2786/54331/59345/51764/94235/55970/2778/2793/5739/2790 19 Human_papillomavirus_type_16 R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 19/4644 19/10654 1.3777572729707358e-7 4.276534190216687e-7 1.5144420885938224e-7 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Human_papillomavirus_type_16 R-HSA-77595 Processing of Intronless Pre-mRNAs 19/4644 19/10654 1.3777572729707358e-7 4.276534190216687e-7 1.5144420885938224e-7 51585/81608/1477/53981/11051/8106/1478/23283/10914/10898/51692/22916/1479/79869/29894/4686/8189/10978/55339 19 Human_papillomavirus_type_16 R-HSA-8851708 Signaling by FGFR2 IIIa TM 19/4644 19/10654 1.3777572729707358e-7 4.276534190216687e-7 1.5144420885938224e-7 5431/5435/5433/5439/5438/2247/2246/2963/5434/5436/2263/2962/5432/22916/5440/5430/5441/4686/5437 19 Human_papillomavirus_type_16 R-HSA-114452 Activation of BH3-only proteins 27/4644 30/10654 1.4017050461343327e-7 4.322180614783448e-7 1.53060678259203e-7 7531/10971/7533/2810/1869/8655/7159/637/23368/7027/7534/10000/7157/7029/140735/7532/5366/8626/208/7161/7529/27113/596/10018/207/5534/5599 27 Human_papillomavirus_type_16 R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 27/4644 30/10654 1.4017050461343327e-7 4.322180614783448e-7 1.53060678259203e-7 4893/817/1741/1739/6196/1740/6197/3845/3265/5923/818/57554/5594/2902/6195/801/805/5170/2904/27330/816/5595/815/1742/88/1385/808 27 Human_papillomavirus_type_16 R-HSA-6804758 Regulation of TP53 Activity through Acetylation 27/4644 30/10654 1.4017050461343327e-7 4.322180614783448e-7 1.53060678259203e-7 64769/84289/29117/5928/1107/5371/23774/3622/27154/57459/10000/7994/3066/7157/5608/7862/9219/5931/1108/54815/208/53615/5305/207/2033/3065/5300 27 Human_papillomavirus_type_16 R-HSA-5654736 Signaling by FGFR1 40/4644 50/10654 1.4502682995627104e-7 4.4621193515054444e-7 1.5801630595420114e-7 5295/4893/2250/5335/2885/5518/2253/3845/3265/7314/5515/5290/5594/2260/2249/6714/2248/2247/6233/2246/2251/5781/6464/673/6654/7311/2549/5595/5516/8822/10253/8817/2254/7316/26281/10818/867/2255/27006/161742 40 Human_papillomavirus_type_16 R-HSA-428930 Thromboxane signalling through TP receptor 22/4644 23/10654 1.5219751489996878e-7 4.652137546942401e-7 1.6474538936540596e-7 2788/2769/2782/2787/10681/2792/2785/2783/2784/2791/6915/2786/54331/59345/51764/94235/55970/2767/2793/9630/2790/10672 22 Human_papillomavirus_type_16 R-HSA-5654695 PI-3K cascade:FGFR2 22/4644 23/10654 1.5219751489996878e-7 4.652137546942401e-7 1.6474538936540596e-7 5295/2250/2885/2252/2253/5290/8823/2249/2248/2247/2246/2251/5781/2263/2549/8822/8817/2254/26281/10818/2255/27006 22 Human_papillomavirus_type_16 R-HSA-5654699 SHC-mediated cascade:FGFR2 22/4644 23/10654 1.5219751489996878e-7 4.652137546942401e-7 1.6474538936540596e-7 4893/2250/2885/2252/2253/3845/3265/8823/2249/2248/2247/2246/2251/6464/2263/6654/8822/8817/2254/26281/2255/27006 22 Human_papillomavirus_type_16 R-HSA-202433 Generation of second messenger molecules 29/4644 33/10654 1.541496854995165e-7 4.68121231073207e-7 1.6577500924076506e-7 5335/3115/3113/3117/3127/5062/3126/916/3702/3932/3120/3937/3123/3122/920/5063/7535/3125/5058/55740/9402/4690/3119/919/27040/915/917/7408/7454 29 Human_papillomavirus_type_16 R-HSA-389356 CD28 co-stimulation 29/4644 33/10654 1.541496854995165e-7 4.68121231073207e-7 1.6577500924076506e-7 5295/941/2534/2885/2475/5062/5879/1326/5290/57761/9020/6714/10000/7525/7409/3932/940/5170/8503/4067/5063/998/208/79109/5058/9402/207/942/5296 29 Human_papillomavirus_type_16 R-HSA-5654726 Negative regulation of FGFR1 signaling 29/4644 33/10654 1.541496854995165e-7 4.68121231073207e-7 1.6577500924076506e-7 2250/2885/5518/2253/7314/5515/5594/2260/2249/6714/2248/2247/6233/2246/2251/5781/673/7311/5595/5516/8822/10253/2254/7316/26281/10818/867/2255/27006 29 Human_papillomavirus_type_16 R-HSA-8951664 Neddylation 141/4644 234/10654 1.62844066952228e-7 4.934562115204663e-7 1.74746844609416e-7 8454/5689/5682/64344/80344/55884/7321/9021/4738/9817/5929/3091/143471/5705/8452/5709/9978/5695/7704/10980/5711/7347/5683/23113/5699/10987/7428/5702/79176/26094/25793/1154/51666/90293/54461/5696/5691/9820/7314/51514/5718/54165/8945/64410/23363/23038/5700/122706/5707/23198/51130/332/7323/9306/4008/84861/1643/9861/6502/90864/55832/5698/5692/5713/26190/10238/5710/9040/5719/6233/83987/127247/26268/115290/51725/140459/10537/8451/899/26224/9655/5931/144699/5706/26263/8450/84078/5714/55527/26272/5688/55336/5687/26270/1161/5708/1642/5704/2873/7311/2034/8533/51667/5694/51138/9318/5684/8065/5720/11091/25879/54850/5690/5717/9491/6500/26259/10197/7316/10213/222235/7322/5715/5701/23291/5685/5686/55294/8453/80176/8139/126433/26043/26267/5716/80204/23014/5693/5721/51676/50813 141 Human_papillomavirus_type_16 R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 38/4644 47/10654 1.7816602649137154e-7 5.352611031421719e-7 1.8955114280159443e-7 4893/71/817/5908/5605/3717/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/369/801/805/283455/3674/409/673/816/60/7529/5595/815/5604/5906/808/5245 38 Human_papillomavirus_type_16 R-HSA-6802949 Signaling by RAS mutants 38/4644 47/10654 1.7816602649137154e-7 5.352611031421719e-7 1.8955114280159443e-7 4893/71/817/5908/5605/3717/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/369/801/805/283455/3674/409/673/816/60/7529/5595/815/5604/5906/808/5245 38 Human_papillomavirus_type_16 R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 38/4644 47/10654 1.7816602649137154e-7 5.352611031421719e-7 1.8955114280159443e-7 4893/71/817/5908/5605/3717/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/369/801/805/283455/3674/409/673/816/60/7529/5595/815/5604/5906/808/5245 38 Human_papillomavirus_type_16 R-HSA-9649948 Signaling downstream of RAS mutants 38/4644 47/10654 1.7816602649137154e-7 5.352611031421719e-7 1.8955114280159443e-7 4893/71/817/5908/5605/3717/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/369/801/805/283455/3674/409/673/816/60/7529/5595/815/5604/5906/808/5245 38 Human_papillomavirus_type_16 R-HSA-199992 trans-Golgi Network Vesicle Budding 53/4644 72/10654 2.1343290276622054e-7 6.398426550876227e-7 2.265864374846066e-7 27131/8773/8906/162/1176/27243/5286/1212/1174/1785/8546/7037/3482/408/6456/7164/3312/1362/25977/10618/6643/10053/6810/8301/9146/8729/4074/2495/152503/6844/1213/2580/1211/8907/351/9685/9026/9829/8905/51429/64746/8673/164/6272/2804/2647/7163/9698/5878/81567/6845/375/4952 53 Human_papillomavirus_type_16 R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 32/4644 38/10654 2.8427381248864193e-7 8.503969273380908e-7 3.011496790363349e-7 5908/1265/3313/6175/3181/4001/4282/5062/1072/6627/9049/27250/9987/3185/3458/5478/302/552900/6775/4478/998/6648/2939/6888/3586/829/5055/6647/6950/4507/375/5721 32 Human_papillomavirus_type_16 R-HSA-933541 TRAF6 mediated IRF7 activation 26/4644 29/10654 2.9116082000331034e-7 8.691460222652009e-7 3.077892654906215e-7 3443/1387/64135/3445/29110/3444/23586/3451/3448/3661/3439/10010/84282/3452/3446/3665/7706/3440/7189/9641/3456/3441/7186/57506/3449/2033 26 Human_papillomavirus_type_16 R-HSA-112043 PLC beta mediated events 42/4644 54/10654 3.0199156668961773e-7 8.995629895234261e-7 3.185607765728005e-7 2780/5331/2770/817/5578/5582/107/814/2773/818/5567/5594/112/5573/111/5613/2771/5580/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5321/5575/114/108/10768/346562/5576/1385/808/5137 42 Human_papillomavirus_type_16 R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 28/4644 32/10654 3.128792492809984e-7 9.280540945903611e-7 3.2865028521337765e-7 51807/10381/10576/7846/7411/81027/10574/10693/5201/79861/5204/10575/10471/10376/5202/84617/10382/7277/347733/10383/60/84790/22948/7280/10694/7203/908/6950 28 Human_papillomavirus_type_16 R-HSA-5626467 RHO GTPases activate IQGAPs 28/4644 32/10654 3.128792492809984e-7 9.280540945903611e-7 3.2865028521337765e-7 71/6249/51807/10381/7846/81027/8826/5879/79861/999/10376/128239/801/4221/805/84617/10382/7277/347733/998/10788/10383/60/84790/7280/1495/1499/808 28 Human_papillomavirus_type_16 R-HSA-3000171 Non-integrin membrane-ECM interactions 45/4644 59/10654 3.1433414263522646e-7 9.304025361122842e-7 3.294819349851808e-7 5578/1280/1289/7448/3688/3910/1290/1605/3690/87/6382/7040/1285/3655/3918/1284/284217/1756/2247/2335/1288/3685/5154/9672/3691/1302/1286/1287/8573/7276/1277/3912/3913/3371/1282/3339/6383/1301/1281/3914/780/5155/7057/1278/4921 45 Human_papillomavirus_type_16 R-HSA-5675482 Regulation of necroptotic cell death 18/4644 18/10654 3.167709977370674e-7 9.317184692350221e-7 3.299479442389845e-7 356/7314/8737/841/8797/6233/8772/331/8717/8743/330/8837/7311/8795/7186/355/7316/329 18 Human_papillomavirus_type_16 R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 18/4644 18/10654 3.167709977370674e-7 9.317184692350221e-7 3.299479442389845e-7 2810/6790/1647/7027/5934/983/7157/7029/891/5111/1874/25946/5933/2033/995/10498/581/3276 18 Human_papillomavirus_type_16 R-HSA-8964315 G beta:gamma signalling through BTK 18/4644 18/10654 3.167709977370674e-7 9.317184692350221e-7 3.299479442389845e-7 2788/2782/2787/10681/2792/2785/2783/2784/2791/695/2786/54331/59345/51764/94235/55970/2793/2790 18 Human_papillomavirus_type_16 R-HSA-202427 Phosphorylation of CD3 and TCR zeta chains 21/4644 22/10654 3.3530103754492594e-7 9.780194504688796e-7 3.4634443532378825e-7 5788/3115/3113/3117/55824/26191/3127/3126/1445/916/3932/3120/3123/3122/920/5795/3125/3119/919/915/917 21 Human_papillomavirus_type_16 R-HSA-5655332 Signaling by FGFR3 in disease 21/4644 22/10654 3.3530103754492594e-7 9.780194504688796e-7 3.4634443532378825e-7 5295/4893/2250/5335/2885/2253/3845/3265/5290/8823/2249/2247/2246/6654/2549/8822/8817/2254/26281/10818/2261 21 Human_papillomavirus_type_16 R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 21/4644 22/10654 3.3530103754492594e-7 9.780194504688796e-7 3.4634443532378825e-7 5295/4893/2250/5335/2885/2253/3845/3265/5290/8823/2249/2247/2246/6654/2549/8822/8817/2254/26281/10818/2261 21 Human_papillomavirus_type_16 R-HSA-912631 Regulation of signaling by CBL 21/4644 22/10654 3.3530103754492594e-7 9.780194504688796e-7 3.4634443532378825e-7 5295/5291/2534/2885/1399/7314/5290/6233/7525/7409/6850/8503/2889/4067/7311/5293/7316/3055/867/1398/5296 21 Human_papillomavirus_type_16 R-HSA-4551638 SUMOylation of chromatin organization proteins 52/4644 71/10654 3.644780464275615e-7 1.0565345023509685e-6 3.7414884278775343e-7 1912/23165/6045/80012/348995/6613/57122/23511/9759/1911/23279/23225/23512/57332/1107/9972/6612/8021/55746/83746/10762/79902/9883/84733/3066/9063/6396/129401/7703/6015/8554/4928/5903/55706/7175/8535/4927/8086/7329/648/23468/81929/9631/79023/23636/53371/9688/7341/3065/23314/6304/8480 52 Human_papillomavirus_type_16 R-HSA-6802957 Oncogenic MAPK signaling 52/4644 71/10654 3.644780464275615e-7 1.0565345023509685e-6 3.7414884278775343e-7 4893/71/817/5908/54845/8546/5605/3717/3690/408/4296/5894/8826/4140/3845/3265/4763/818/8805/8844/7094/5594/7414/10533/23164/6714/9061/2335/1445/369/801/805/283455/3674/409/673/816/56829/60/7529/5595/4000/27044/815/22906/8087/5604/10018/10142/5906/808/5245 52 Human_papillomavirus_type_16 R-HSA-70171 Glycolysis 52/4644 71/10654 3.644780464275615e-7 1.0565345023509685e-6 3.7414884278775343e-7 23165/7167/5211/348995/57122/3099/23511/23279/23225/9972/5518/8021/2026/55746/5515/2597/5567/10762/5528/79902/5519/9883/226/2821/6396/129401/230/4928/5903/55706/7175/5568/4927/5566/2023/8086/5516/81929/9631/5315/79023/23636/5214/53371/5230/3098/9688/5210/5209/5224/5213/8480 52 Human_papillomavirus_type_16 R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 40/4644 51/10654 3.890450502117144e-7 1.1254231040145057e-6 3.985442511121633e-7 51807/10381/1780/5048/8655/84516/832/636/7846/81027/51164/79861/23299/8398/10376/10540/140735/84617/11258/1783/10382/93661/55860/830/7277/10671/1639/347733/51143/10383/84790/5049/7280/829/22931/1778/5321/5050/1781/10121 40 Human_papillomavirus_type_16 R-HSA-392451 G beta:gamma signalling through PI3Kgamma 23/4644 25/10654 5.032934917742362e-7 1.4381278390208827e-6 5.092818696911555e-7 2788/2782/2787/10681/2792/10000/5294/2785/2783/2784/2791/5170/2786/208/387/54331/59345/207/51764/94235/55970/2793/2790 23 Human_papillomavirus_type_16 R-HSA-418592 ADP signalling through P2Y purinoceptor 1 23/4644 25/10654 5.032934917742362e-7 1.4381278390208827e-6 5.092818696911555e-7 2788/2769/1432/2782/2787/10681/2792/6714/2785/2783/2784/2791/2786/5321/54331/59345/51764/94235/55970/2767/2793/9630/2790 23 Human_papillomavirus_type_16 R-HSA-5654700 FRS-mediated FGFR2 signaling 23/4644 25/10654 5.032934917742362e-7 1.4381278390208827e-6 5.092818696911555e-7 4893/2250/2885/2252/2253/3845/3265/8823/2249/2248/2247/2246/2251/5781/2263/6654/8822/8817/2254/26281/10818/2255/27006 23 Human_papillomavirus_type_16 R-HSA-5654708 Downstream signaling of activated FGFR3 23/4644 25/10654 5.032934917742362e-7 1.4381278390208827e-6 5.092818696911555e-7 5295/4893/2250/5335/2885/2253/3845/3265/5290/8823/2249/2247/2246/5781/6464/6654/2549/8822/8817/2254/26281/10818/2261 23 Human_papillomavirus_type_16 R-HSA-9006115 Signaling by NTRK2 (TRKB) 23/4644 25/10654 5.032934917742362e-7 1.4381278390208827e-6 5.092818696911555e-7 5295/627/4893/5335/2534/2885/3845/3265/5879/5290/6714/4909/5781/4908/6464/2904/7074/6654/2549/1020/4915/10818/8851 23 Human_papillomavirus_type_16 R-HSA-9006335 Signaling by Erythropoietin 23/4644 25/10654 5.032934917742362e-7 1.4381278390208827e-6 5.092818696911555e-7 5295/4893/5335/5291/6776/3717/2885/2056/8660/3845/3265/1399/5290/5336/5294/7409/6777/6464/2889/4067/6654/5293/2549 23 Human_papillomavirus_type_16 R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 47/4644 63/10654 5.377350136270187e-7 1.5334191547128195e-6 5.430272281385384e-7 4790/5435/4792/3428/1387/22954/1660/3551/7314/11035/8737/29110/81844/8517/6778/51428/5970/3661/6233/11128/4791/9533/3665/5434/23220/7098/9208/5591/7311/171568/2547/1147/170506/5440/6737/1499/7520/147945/5441/51082/4615/7316/27297/4793/5437/2033/148022 47 Human_papillomavirus_type_16 R-HSA-202040 G-protein activation 25/4644 28/10654 6.02551363011228e-7 1.711294660535937e-6 6.060179913515867e-7 2788/2780/2770/4988/2782/2773/2787/10681/5443/2792/2785/2783/2784/2771/2791/2786/54331/59345/51764/94235/5173/55970/346562/2793/2790 25 Human_papillomavirus_type_16 R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 25/4644 28/10654 6.02551363011228e-7 1.711294660535937e-6 6.060179913515867e-7 10381/10576/7846/7411/81027/10574/10693/5201/5204/10575/10471/5202/84617/10382/7277/347733/10383/60/84790/22948/7280/10694/7203/908/6950 25 Human_papillomavirus_type_16 R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 29/4644 34/10654 6.094544024132781e-7 1.727403084011776e-6 6.117224411250767e-7 7321/9474/3093/64135/83737/7187/1540/7314/29110/9636/8887/7323/23586/7128/3661/51191/6233/55593/84282/7706/9246/7311/5094/9641/57506/7316/7322/54941/5300 29 Human_papillomavirus_type_16 R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 27/4644 31/10654 6.32409734049467e-7 1.7852532331416544e-6 6.322088202294789e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/79023/23636/53371/9688/8480 27 Human_papillomavirus_type_16 R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 27/4644 31/10654 6.32409734049467e-7 1.7852532331416544e-6 6.322088202294789e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/79023/23636/53371/9688/8480 27 Human_papillomavirus_type_16 R-HSA-8856688 Golgi-to-ER retrograde transport 86/4644 133/10654 6.886195871711884e-7 1.9400266682754566e-6 6.870184847702409e-7 11014/64837/51807/5861/10381/1780/5048/8655/84516/832/285643/10112/636/7846/81027/11004/10749/81930/54732/51164/60561/79861/3797/29127/55605/23299/8398/1315/3796/11316/89953/56992/8729/10376/1314/10540/3835/3833/378/9493/26286/26958/140735/84364/22820/84617/11258/1783/9585/10382/93661/55860/830/3832/7277/10671/23303/1639/81876/9183/1062/347733/51143/10383/24137/84790/84643/5049/7280/829/22931/1778/5321/5050/63908/1781/10121/547/10972/381/4905/9276/55083/3799/375/372 86 Human_papillomavirus_type_16 R-HSA-164378 PKA activation in glucagon signalling 17/4644 17/10654 7.282241415451006e-7 2.023165288292626e-6 7.164602288885618e-7 107/5567/112/5573/111/196883/115/5568/113/5566/5577/109/5575/114/108/2778/5576 17 Human_papillomavirus_type_16 R-HSA-180292 GAB1 signalosome 17/4644 17/10654 7.282241415451006e-7 2.023165288292626e-6 7.164602288885618e-7 5295/374/7039/55824/2885/5829/1839/5290/2069/6714/1445/255324/5781/1956/2549/685/1950 17 Human_papillomavirus_type_16 R-HSA-432142 Platelet sensitization by LDL 17/4644 17/10654 7.282241415451006e-7 2.023165288292626e-6 7.164602288885618e-7 5777/5526/5175/2268/1432/5518/5515/5528/5519/5781/338/5529/5516/5321/5525/5527/7804 17 Human_papillomavirus_type_16 R-HSA-450604 KSRP (KHSRP) binds and destabilizes mRNA 17/4644 17/10654 7.282241415451006e-7 2.023165288292626e-6 7.164602288885618e-7 5393/23404/1432/11340/7534/5600/8570/23016/118460/5073/51010/56915/167227/22894/207/51013/54512 17 Human_papillomavirus_type_16 R-HSA-5655862 Translesion synthesis by POLK 17/4644 17/10654 7.282241415451006e-7 2.023165288292626e-6 7.164602288885618e-7 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/51426/7311/5983/7316/10459/5981/5980 17 Human_papillomavirus_type_16 R-HSA-5656121 Translesion synthesis by POLI 17/4644 17/10654 7.282241415451006e-7 2.023165288292626e-6 7.164602288885618e-7 5982/6117/7314/6118/11201/51455/5985/5984/6233/5111/6119/7311/5983/7316/10459/5981/5980 17 Human_papillomavirus_type_16 R-HSA-8934593 Regulation of RUNX1 Expression and Activity 17/4644 17/10654 7.282241415451006e-7 2.023165288292626e-6 7.164602288885618e-7 27327/192669/5371/4343/865/6714/595/896/26523/5781/27161/894/57690/192670/1021/861/23112 17 Human_papillomavirus_type_16 R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 20/4644 21/10654 7.371755431676115e-7 2.0399552013099784e-6 7.224060134436056e-7 2237/5982/6117/10714/6118/328/3978/5985/5984/5424/54107/5425/5111/6119/5427/5983/56655/57804/5426/5981 20 Human_papillomavirus_type_16 R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 20/4644 21/10654 7.371755431676115e-7 2.0399552013099784e-6 7.224060134436056e-7 25904/55571/55835/57472/85456/29883/1263/7832/10769/7157/5325/4869/4850/246175/4848/23019/4849/9337/28984/995 20 Human_papillomavirus_type_16 R-HSA-112040 G-protein mediated events 42/4644 55/10654 7.389994890104897e-7 2.0409769352002304e-6 7.227678384023026e-7 2780/5331/2770/817/5578/5582/107/814/2773/818/5567/5594/112/5573/111/5613/2771/5580/196883/115/801/805/3838/5568/113/10645/5566/84254/816/5577/109/815/5321/5575/114/108/10768/346562/5576/1385/808/5137 42 Human_papillomavirus_type_16 R-HSA-5628897 TP53 Regulates Metabolic Genes 60/4644 86/10654 7.636287884791833e-7 2.103392452349522e-6 7.448709438488761e-7 5563/7531/10971/9997/27327/7295/7533/2810/53632/7001/192669/2475/4513/4343/7296/9377/51422/7249/27244/7534/1351/2821/10000/2877/54541/7157/1337/50484/26523/2744/57521/83667/7532/1345/5571/10128/6009/8626/208/5562/4697/5564/5565/7248/7529/27161/27165/207/57690/192670/2539/54205/143686/1350/5728/23112/10542/1349/1327/5052 60 Human_papillomavirus_type_16 R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 34/4644 42/10654 7.645973989296195e-7 2.103392452349522e-6 7.448709438488761e-7 2788/2740/9495/2782/8826/2787/5567/10681/112/5573/111/2792/2785/2783/2784/2791/5568/5566/2641/2786/5577/54331/5575/59345/51764/94235/114/3790/55970/2778/2793/5576/5906/2790 34 Human_papillomavirus_type_16 R-HSA-112315 Transmission across Chemical Synapses 158/4644 272/10654 7.985753047563457e-7 2.1925658563075405e-6 7.764497761767335e-7 2788/5563/4893/5579/5331/23426/2900/2770/51807/817/2550/5578/2898/5582/53632/10381/9463/107/9568/8500/81539/7846/9495/2782/81027/1134/1741/6531/1739/163/6196/1740/10368/8874/2897/6197/8825/3845/3265/3312/814/2773/5879/2787/5923/818/57554/161/79861/5567/4646/5594/8499/51422/10681/112/2892/5573/2902/111/2901/2792/3359/6714/2752/2567/2785/10376/6195/2783/2784/83988/5613/2771/6844/196883/3759/115/1175/801/2891/2744/2791/805/5170/1173/84617/320/3838/59283/8573/6857/2904/2890/10382/2556/5568/2036/7277/5864/160/113/6616/10645/2899/55327/5566/84254/5571/27330/347733/3084/816/3763/2786/5577/10369/2893/5562/10383/84790/5564/5565/7280/109/5595/64130/815/27165/54331/28964/3761/5575/59345/51764/94235/114/108/55970/346562/2793/5576/2903/6572/4137/1103/2066/4905/27092/9647/1742/88/1385/3768/808/8536/4193/2790 158 Human_papillomavirus_type_16 R-HSA-6802952 Signaling by BRAF and RAF fusions 49/4644 67/10654 8.52059688158101e-7 2.3348432470426087e-6 8.268342368639467e-7 4893/71/817/5908/54845/8546/5605/3717/3690/408/5894/8826/4140/3845/3265/818/8805/8844/7094/5594/7414/10533/23164/6714/9061/2335/1445/369/801/805/283455/3674/409/673/816/56829/60/7529/5595/4000/27044/815/22906/8087/5604/10018/10142/5906/808 49 Human_papillomavirus_type_16 R-HSA-977444 GABA B receptor activation 32/4644 39/10654 9.195748363829714e-7 2.510045710983091e-6 8.888784001080535e-7 2788/2770/2550/107/9568/2782/2773/2787/112/111/2792/2785/2783/2784/2771/196883/3759/115/113/3763/2786/109/54331/3761/94235/114/108/55970/346562/2793/3768/2790 32 Human_papillomavirus_type_16 R-HSA-991365 Activation of GABAB receptors 32/4644 39/10654 9.195748363829714e-7 2.510045710983091e-6 8.888784001080535e-7 2788/2770/2550/107/9568/2782/2773/2787/112/111/2792/2785/2783/2784/2771/196883/3759/115/113/3763/2786/109/54331/3761/94235/114/108/55970/346562/2793/3768/2790 32 Human_papillomavirus_type_16 R-HSA-450302 activated TAK1 mediates p38 MAPK activation 22/4644 24/10654 1.0678787518163274e-6 2.892343414668547e-6 1.0242608633556322e-6 1432/3654/7334/7314/257397/5606/8767/23118/8517/9261/10454/6233/5600/5608/7867/64127/3656/7189/7311/6885/10392/7316 22 Human_papillomavirus_type_16 R-HSA-5627123 RHO GTPases activate PAKs 22/4644 24/10654 1.0678787518163274e-6 2.892343414668547e-6 1.0242608633556322e-6 2017/79784/4628/5062/5879/4638/4659/4771/801/5500/805/2316/10627/5063/998/5058/3984/4627/10398/4637/103910/808 22 Human_papillomavirus_type_16 R-HSA-8940973 RUNX2 regulates osteoblast differentiation 22/4644 24/10654 1.0678787518163274e-6 2.892343414668547e-6 1.0242608633556322e-6 5925/10413/25/5594/3280/10013/632/2737/865/6714/7525/1277/23493/367/860/5595/8841/23462/4094/23314/25925/25937 22 Human_papillomavirus_type_16 R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 22/4644 24/10654 1.0678787518163274e-6 2.892343414668547e-6 1.0242608633556322e-6 374/7039/1839/5594/2069/10000/595/7514/2353/255324/5747/208/1956/5595/596/685/2309/207/1027/1950/2002/1385 22 Human_papillomavirus_type_16 R-HSA-2871809 FCERI mediated Ca+2 mobilization 28/4644 33/10654 1.2017648064572867e-6 3.2487013939490816e-6 1.1504573342416376e-6 5335/5530/2885/4773/5336/7410/7409/3702/801/805/6464/2205/4772/3937/4775/10451/2206/6850/4067/695/6654/9402/5532/10768/27040/5534/808/2207 28 Human_papillomavirus_type_16 R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress 24/4644 27/10654 1.2420140852596343e-6 3.344617584681894e-6 1.1844239786696583e-6 5393/23404/3576/4801/6347/11340/468/1054/8570/23016/118460/5073/1051/4800/51010/56915/167227/22894/440/4802/1649/51013/467/54512 24 Human_papillomavirus_type_16 R-HSA-5654716 Downstream signaling of activated FGFR4 24/4644 27/10654 1.2420140852596343e-6 3.344617584681894e-6 1.1844239786696583e-6 5295/4893/5335/9965/2264/2885/2253/3845/3265/5290/8823/2249/2247/2246/2251/5781/6464/6654/2549/8822/8817/2254/26281/10818 24 Human_papillomavirus_type_16 R-HSA-2424491 DAP12 signaling 26/4644 30/10654 1.2725978700375117e-6 3.4204115165950743e-6 1.2112647603502835e-6 5295/4893/5335/5291/3824/567/2534/2885/3133/3845/3265/5879/5290/5336/7410/3932/6464/3937/10451/6850/22914/695/6654/9402/27040/5296 26 Human_papillomavirus_type_16 R-HSA-8853659 RET signaling 33/4644 41/10654 1.4330190244099562e-6 3.844217382881776e-6 1.3613464416252376e-6 5295/2674/1796/5335/5291/5578/55816/2668/2885/8660/9846/5290/5567/6714/5598/220164/9260/55715/5781/6464/5568/5566/8503/2886/6654/5293/2549/10818/53358/5979/5296/2887/9046 33 Human_papillomavirus_type_16 R-HSA-164938 Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 19/4644 20/10654 1.6170996859292063e-6 4.305105994988e-6 1.5245601752892946e-6 162/1174/567/163/55690/51606/161/10053/926/3932/1175/8907/940/1173/160/920/8905/164/375 19 Human_papillomavirus_type_16 R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 19/4644 20/10654 1.6170996859292063e-6 4.305105994988e-6 1.5245601752892946e-6 472/1387/51499/7159/637/27166/23368/7157/63970/55240/5366/84883/147923/94241/8626/7161/665/27113/581 19 Human_papillomavirus_type_16 R-HSA-8964616 G beta:gamma signalling through CDC42 19/4644 20/10654 1.6170996859292063e-6 4.305105994988e-6 1.5245601752892946e-6 2788/2782/2787/10681/2792/2785/2783/2784/2791/998/2786/5058/54331/59345/51764/94235/55970/2793/2790 19 Human_papillomavirus_type_16 R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 19/4644 20/10654 1.6170996859292063e-6 4.305105994988e-6 1.5245601752892946e-6 22938/1387/4088/4853/9794/2648/55534/3280/84441/8850/2324/10046/59/4855/23493/4851/23462/2033/3516 19 Human_papillomavirus_type_16 R-HSA-110312 Translesion synthesis by REV1 16/4644 16/10654 1.673908474018323e-6 4.381517890014379e-6 1.5516197952408655e-6 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/7311/5983/7316/10459/5981/5980 16 Human_papillomavirus_type_16 R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 16/4644 16/10654 1.673908474018323e-6 4.381517890014379e-6 1.5516197952408655e-6 1869/5928/7027/5934/890/983/7029/286826/91750/1874/55957/4605/1875/5933/3065/132660 16 Human_papillomavirus_type_16 R-HSA-156711 Polo-like kinase mediated events 16/4644 16/10654 1.673908474018323e-6 4.381517890014379e-6 1.5516197952408655e-6 5928/7465/993/2305/9133/286826/891/91750/55957/5347/4605/1063/9088/2033/995/132660 16 Human_papillomavirus_type_16 R-HSA-193639 p75NTR signals via NF-kB 16/4644 16/10654 1.673908474018323e-6 4.381517890014379e-6 1.5516197952408655e-6 4790/8878/4792/3654/3551/7314/8767/5970/6233/7189/7311/4804/5584/4615/7316/4803 16 Human_papillomavirus_type_16 R-HSA-1963640 GRB2 events in ERBB2 signaling 16/4644 16/10654 1.673908474018323e-6 4.381517890014379e-6 1.5516197952408655e-6 4893/2064/145957/9542/2885/3845/3265/1839/2069/3084/6654/10718/1956/685/1950/2066 16 Human_papillomavirus_type_16 R-HSA-1963642 PI3K events in ERBB2 signaling 16/4644 16/10654 1.673908474018323e-6 4.381517890014379e-6 1.5516197952408655e-6 5295/2064/145957/9542/2885/1839/5290/2065/2069/3084/10718/1956/2549/685/1950/2066 16 Human_papillomavirus_type_16 R-HSA-399954 Sema3A PAK dependent Axon repulsion 16/4644 16/10654 1.673908474018323e-6 4.381517890014379e-6 1.5516197952408655e-6 5361/8829/2534/5362/5062/5879/1072/10371/55558/5063/3326/5058/3984/3320/91584/2242 16 Human_papillomavirus_type_16 R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 16/4644 16/10654 1.673908474018323e-6 4.381517890014379e-6 1.5516197952408655e-6 8454/4790/3551/7314/8945/1326/8517/6233/79155/7311/6416/1147/5604/6500/7316/23291 16 Human_papillomavirus_type_16 R-HSA-9614657 FOXO-mediated transcription of cell death genes 16/4644 16/10654 1.673908474018323e-6 4.381517890014379e-6 1.5516197952408655e-6 2308/65018/356/1387/4801/604/4303/4800/10370/6794/27113/2309/10018/4802/1649/2033 16 Human_papillomavirus_type_16 R-HSA-114604 GPVI-mediated activation cascade 29/4644 35/10654 2.068330172223109e-6 5.403849593350133e-6 1.9136564565114326e-6 5295/5777/5291/388/2534/5879/5290/5336/5880/5294/7410/7409/3932/5781/5170/5590/3937/10451/1277/6850/8503/4067/998/387/27040/391/5296/1278/2207 29 Human_papillomavirus_type_16 R-HSA-389948 PD-1 signaling 21/4644 23/10654 2.2578880253169636e-6 5.87721131636308e-6 2.0812872726288583e-6 5777/3115/3113/3117/3127/3126/29126/1445/916/3932/5781/3120/3123/80380/3122/920/3125/3119/919/915/917 21 Human_papillomavirus_type_16 R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 21/4644 23/10654 2.2578880253169636e-6 5.87721131636308e-6 2.0812872726288583e-6 3654/7334/7314/257397/5601/8767/23118/8517/10454/6233/64127/5602/3656/7189/7311/6416/6885/10392/7316/5609/5599 21 Human_papillomavirus_type_16 R-HSA-397795 G-protein beta:gamma signalling 27/4644 32/10654 2.3578743517991948e-6 6.114783208085528e-6 2.1654182197669424e-6 2788/5331/2782/2787/10681/2792/10000/5294/2785/2783/2784/2791/5170/998/695/2786/208/387/5058/54331/59345/207/51764/94235/55970/2793/2790 27 Human_papillomavirus_type_16 R-HSA-8941326 RUNX2 regulates bone development 27/4644 32/10654 2.3578743517991948e-6 6.114783208085528e-6 2.1654182197669424e-6 5925/9759/10413/4089/25/5594/3280/10013/632/2737/865/6714/7525/10432/1277/2736/23493/367/860/5595/8841/23462/4086/4094/23314/25925/25937 27 Human_papillomavirus_type_16 R-HSA-5218920 VEGFR2 mediated vascular permeability 25/4644 29/10654 2.5487422568107094e-6 6.550417330911676e-6 2.3196886222683053e-6 857/2475/5062/5879/57761/1500/10000/3728/7410/7409/801/805/5170/10451/1003/5063/208/79109/5058/1495/1499/207/3320/4846/808 25 Human_papillomavirus_type_16 R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 25/4644 29/10654 2.5487422568107094e-6 6.550417330911676e-6 2.3196886222683053e-6 5431/5435/5433/55124/84944/5439/11022/91646/5438/56165/54514/5434/5436/122402/143689/5432/5440/8468/5430/5441/5437/3320/54456/9271/136991 25 Human_papillomavirus_type_16 R-HSA-9619483 Activation of AMPK downstream of NMDARs 25/4644 29/10654 2.5487422568107094e-6 6.550417330911676e-6 2.3196886222683053e-6 5563/51807/53632/10381/7846/81027/79861/51422/10376/801/805/84617/10382/7277/10645/5571/347733/5562/10383/84790/5564/5565/7280/4137/808 25 Human_papillomavirus_type_16 R-HSA-6803529 FGFR2 alternative splicing 23/4644 26/10654 2.549200187225784e-6 6.550417330911676e-6 2.3196886222683053e-6 54845/5431/5435/5433/5439/7073/5438/3185/4670/5725/2963/5434/5436/2962/5432/22916/5440/5430/3178/5441/4686/5437/3187 23 Human_papillomavirus_type_16 R-HSA-912694 Regulation of IFNA signaling 23/4644 26/10654 2.549200187225784e-6 6.550417330911676e-6 2.3196886222683053e-6 3443/5777/5770/9021/3445/3444/3451/3448/3439/3452/6773/7297/5781/3446/3455/6772/8651/3440/3454/3716/3456/3441/3449 23 Human_papillomavirus_type_16 R-HSA-3247509 Chromatin modifying enzymes 157/4644 274/10654 2.6618930443259125e-6 6.815029089761415e-6 2.4133951535186914e-6 9643/9070/4790/79718/64769/51742/79595/10474/9112/10445/5929/79813/7403/54556/84289/9612/6603/5926/27097/55818/5928/1387/56950/3717/6907/23081/23512/1107/79084/57492/22992/26610/6881/10499/1386/55689/3054/51230/10284/8089/55170/23774/84661/8464/9869/196528/2648/23186/55869/2146/1788/51147/6871/23569/86/83933/5970/51412/64426/79685/8850/55352/27154/57459/6604/8289/84159/6602/55929/595/7994/8473/3066/23067/10419/8607/8726/6883/10765/4791/55193/55904/84678/6595/5077/1019/5927/29943/23326/84148/7862/6597/9219/5931/8520/6599/8819/11143/63976/1108/2122/84444/10524/54815/23210/9682/55693/57504/58508/23030/57634/6880/60/6601/6187/53615/10362/4297/55140/121536/10196/8295/8841/55167/11091/8242/5978/8085/6839/25855/284058/6598/117143/5253/10629/26009/9611/2874/10856/29072/10933/2033/6605/3065/23028/23135/10498/9757/80854/51317/9739/10902/3276/9913/8648/64754/10919 157 Human_papillomavirus_type_16 R-HSA-4839726 Chromatin organization 157/4644 274/10654 2.6618930443259125e-6 6.815029089761415e-6 2.4133951535186914e-6 9643/9070/4790/79718/64769/51742/79595/10474/9112/10445/5929/79813/7403/54556/84289/9612/6603/5926/27097/55818/5928/1387/56950/3717/6907/23081/23512/1107/79084/57492/22992/26610/6881/10499/1386/55689/3054/51230/10284/8089/55170/23774/84661/8464/9869/196528/2648/23186/55869/2146/1788/51147/6871/23569/86/83933/5970/51412/64426/79685/8850/55352/27154/57459/6604/8289/84159/6602/55929/595/7994/8473/3066/23067/10419/8607/8726/6883/10765/4791/55193/55904/84678/6595/5077/1019/5927/29943/23326/84148/7862/6597/9219/5931/8520/6599/8819/11143/63976/1108/2122/84444/10524/54815/23210/9682/55693/57504/58508/23030/57634/6880/60/6601/6187/53615/10362/4297/55140/121536/10196/8295/8841/55167/11091/8242/5978/8085/6839/25855/284058/6598/117143/5253/10629/26009/9611/2874/10856/29072/10933/2033/6605/3065/23028/23135/10498/9757/80854/51317/9739/10902/3276/9913/8648/64754/10919 157 Human_papillomavirus_type_16 R-HSA-6807505 RNA polymerase II transcribes snRNA genes 52/4644 74/10654 2.9508294588855002e-6 7.541008617151833e-6 2.670485101320978e-6 6884/51585/5431/5435/5433/2960/55656/5439/904/65123/55197/2959/79871/5438/6667/23248/1025/6829/2957/2963/5434/26173/5436/26512/6878/58490/2962/8812/905/64859/6880/6908/80237/6619/6882/2961/5432/22916/6877/5440/5430/5451/6617/5441/4686/5437/6827/80789/51593/79035/1022/8178 52 Human_papillomavirus_type_16 R-HSA-202430 Translocation of ZAP-70 to Immunological synapse 18/4644 19/10654 3.5386858656569625e-6 9.01048324776174e-6 3.1908677592703914e-6 3115/3113/3117/26191/3127/3126/916/3932/3120/3123/3122/920/7535/3125/3119/919/915/917 18 Human_papillomavirus_type_16 R-HSA-6804760 Regulation of TP53 Activity through Methylation 18/4644 19/10654 3.5386858656569625e-6 9.01048324776174e-6 3.1908677592703914e-6 133383/11200/472/79813/4194/56950/7314/7157/6233/10419/26013/7311/7316/2033/91875/133746/10919/4193 18 Human_papillomavirus_type_16 R-HSA-72766 Translation 165/4644 291/10654 3.5507858235467164e-6 9.024913968181237e-6 3.195978086792621e-6 6158/6138/5464/6227/6206/1965/6234/27335/6191/6128/6132/84545/6129/1915/26284/80222/6176/8668/6224/6146/6154/8662/26986/6202/65003/6169/6175/6218/6173/6167/6156/6143/1973/124995/28973/51116/6139/64975/3921/8665/65005/6208/6170/6203/10952/6147/8666/6222/64432/8667/6727/7818/6184/58477/2935/6134/6747/6731/55699/6155/6729/6231/6142/7458/8663/23521/23107/8894/1981/6207/64978/1977/6233/28957/51386/6188/1978/64965/7284/6122/1968/6230/8669/6194/2107/6166/1938/1650/1983/6136/6125/1937/6232/6160/6748/29927/1933/6193/6210/6229/6205/54148/64976/140801/23438/79587/6235/6181/8893/1975/23471/7311/6223/25873/8664/6730/9045/6187/6168/6157/6137/1974/55037/51264/6144/9349/4736/8891/51121/65993/6159/56945/6217/1936/6152/79590/51065/6141/10480/1967/6164/63931/8661/9669/6209/1964/11224/6130/8890/6204/64969/6228/7965/6124/2193/3646/6189/9789/6135/6201/6161/51649/54998/8892/6133 165 Human_papillomavirus_type_16 R-HSA-5099900 WNT5A-dependent internalization of FZD4 15/4644 15/10654 3.847205066986592e-6 9.655865311238263e-6 3.4194158584270253e-6 5579/5578/1212/5582/163/161/1856/8322/7474/1213/1211/1175/1173/409/160 15 Human_papillomavirus_type_16 R-HSA-5358508 Mismatch Repair 15/4644 15/10654 3.847205066986592e-6 9.655865311238263e-6 3.4194158584270253e-6 4436/9156/6117/10714/4437/6118/3978/5424/2956/4292/5425/5111/6119/57804/5395 15 Human_papillomavirus_type_16 R-HSA-5637810 Constitutive Signaling by EGFRvIII 15/4644 15/10654 3.847205066986592e-6 9.655865311238263e-6 3.4194158584270253e-6 5295/4893/5335/2885/3845/3265/5290/6464/6654/1956/2549/11140/1950/867/3320 15 Human_papillomavirus_type_16 R-HSA-5637812 Signaling by EGFRvIII in Cancer 15/4644 15/10654 3.847205066986592e-6 9.655865311238263e-6 3.4194158584270253e-6 5295/4893/5335/2885/3845/3265/5290/6464/6654/1956/2549/11140/1950/867/3320 15 Human_papillomavirus_type_16 R-HSA-6785631 ERBB2 Regulates Cell Motility 15/4644 15/10654 3.847205066986592e-6 9.655865311238263e-6 3.4194158584270253e-6 2064/145957/9542/1839/2065/2069/1729/3084/10718/387/1956/685/1950/51072/2066 15 Human_papillomavirus_type_16 R-HSA-69183 Processive synthesis on the lagging strand 15/4644 15/10654 3.847205066986592e-6 9.655865311238263e-6 3.4194158584270253e-6 2237/1763/5422/6117/10714/5558/6118/3978/5557/23649/5424/5425/5111/6119/57804 15 Human_papillomavirus_type_16 R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 15/4644 15/10654 3.847205066986592e-6 9.655865311238263e-6 3.4194158584270253e-6 6456/30011/2885/7314/8027/2060/9146/6455/6233/4233/7311/7316/867/10254/6457 15 Human_papillomavirus_type_16 R-HSA-74752 Signaling by Insulin receptor 54/4644 78/10654 3.949775584590664e-6 9.89559847353697e-6 3.504312172794725e-6 5295/4893/2250/5291/535/50617/10312/9965/2264/3630/2885/8660/9846/2252/2253/3845/3265/54106/51606/5290/3667/8823/9114/5594/57761/2260/2249/2248/2247/2246/2251/523/5781/5170/6464/2322/2263/208/6654/2549/5595/8822/8817/2254/5289/26281/10818/23545/2261/2255/27006/5296/9296/2887 54 Human_papillomavirus_type_16 R-HSA-75153 Apoptotic execution phase 39/4644 52/10654 4.032824873552787e-6 1.0085656501951088e-5 3.571617112894109e-6 10059/660/836/324/9414/4001/3836/6709/6093/840/5062/2934/63967/841/100506658/7082/5339/28988/10134/999/5588/5580/839/1828/5747/118/1829/8428/1832/3148/4000/3837/51765/1499/3146/329/4137/7431/6304 39 Human_papillomavirus_type_16 R-HSA-198753 ERK/MAPK targets 20/4644 22/10654 4.75592059939449e-6 1.1830774115160407e-5 4.189612771396415e-6 9252/1432/6196/5518/6197/51231/5515/1849/5594/5528/5519/5598/4208/6195/5600/5595/5516/1845/4205/2002 20 Human_papillomavirus_type_16 R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 20/4644 22/10654 4.75592059939449e-6 1.1830774115160407e-5 4.189612771396415e-6 3725/7531/356/7001/4001/826/823/2801/993/351/6648/1020/4000/994/2309/10018/831/995/8851/5052 20 Human_papillomavirus_type_16 R-HSA-8863678 Neurodegenerative Diseases 20/4644 22/10654 4.75592059939449e-6 1.1830774115160407e-5 4.189612771396415e-6 3725/7531/356/7001/4001/826/823/2801/993/351/6648/1020/4000/994/2309/10018/831/995/8851/5052 20 Human_papillomavirus_type_16 R-HSA-70326 Glucose metabolism 61/4644 91/10654 5.05094216298477e-6 1.2542428061358644e-5 4.441629624459827e-6 23165/7167/2806/5211/348995/57122/3099/6576/23511/23279/5106/23225/9972/5518/4191/8021/2026/55746/5515/2597/5567/10762/5528/79902/5519/9883/226/2821/6396/129401/230/5105/4928/5903/55706/7175/5568/2805/4927/5566/2023/4190/8086/5516/81929/9631/5091/5315/79023/23636/5214/53371/5230/10165/3098/9688/5210/5209/5224/5213/8480 61 Human_papillomavirus_type_16 R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 22/4644 25/10654 5.208170658791672e-6 1.2864548299797037e-5 4.555701539936378e-6 9252/1432/6196/5518/6197/51231/5515/1849/5594/5528/9261/5519/5598/4208/6195/5600/5595/5516/1845/4205/2002/1385 22 Human_papillomavirus_type_16 R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 22/4644 25/10654 5.208170658791672e-6 1.2864548299797037e-5 4.555701539936378e-6 51807/10381/10576/7846/81027/10574/10693/79861/10575/10376/84617/10382/7277/347733/10383/84790/22948/7280/10694/7203/908/6950 22 Human_papillomavirus_type_16 R-HSA-400685 Sema4D in semaphorin signaling 22/4644 25/10654 5.208170658791672e-6 1.2864548299797037e-5 4.555701539936378e-6 2909/388/2064/23365/79784/9475/4628/6093/10507/5879/27289/389/5364/10627/4233/387/3984/4627/3985/10398/4637/103910 22 Human_papillomavirus_type_16 R-HSA-167287 HIV elongation arrest and recovery 29/4644 36/10654 6.192583925843205e-6 1.5242447803435116e-5 5.397783218832859e-6 5431/5435/5433/5439/11198/904/51497/5438/1025/7936/6829/25920/2963/5434/5436/2962/8812/905/5432/6917/5440/5430/6749/5441/7469/9150/5437/6827/8178 29 Human_papillomavirus_type_16 R-HSA-167290 Pausing and recovery of HIV elongation 29/4644 36/10654 6.192583925843205e-6 1.5242447803435116e-5 5.397783218832859e-6 5431/5435/5433/5439/11198/904/51497/5438/1025/7936/6829/25920/2963/5434/5436/2962/8812/905/5432/6917/5440/5430/6749/5441/7469/9150/5437/6827/8178 29 Human_papillomavirus_type_16 R-HSA-3928665 EPH-ephrin mediated repulsion of cells 38/4644 51/10654 7.0179977207904085e-6 1.724387180782652e-5 6.106544242258407e-6 71/2042/1212/23385/2051/2047/2534/163/1759/5879/161/4313/2041/102/6714/1943/2043/7525/1942/7410/1213/1211/1175/5663/1173/7074/1949/1945/10451/4318/160/8218/4067/2048/60/1946/1944/1969 38 Human_papillomavirus_type_16 R-HSA-8875878 MET promotes cell motility 32/4644 41/10654 7.072911032465157e-6 1.7348416396064016e-5 6.143566447043714e-6 3675/5908/3082/1280/1289/3688/3910/1290/2885/1399/5879/3918/284217/6714/2335/64759/84951/1302/85440/5747/1277/3912/4233/2889/3913/2549/1301/1281/3914/1398/5906/1278 32 Human_papillomavirus_type_16 R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 27/4644 33/10654 7.560367305837817e-6 1.8511684694747744e-5 6.555512755314504e-6 4790/4792/3654/7334/3551/7314/257397/8767/23118/8517/5970/10454/6233/4791/351/64127/3656/7189/7311/1147/6885/10392/7316/4793/3146/6288/6285 27 Human_papillomavirus_type_16 R-HSA-5654221 Phospholipase C-mediated cascade; FGFR2 17/4644 18/10654 7.722927586281689e-6 1.877862634931232e-5 6.6500443687402304e-6 2250/5335/2252/2253/8823/2249/2248/2247/2246/2251/2263/8822/8817/2254/26281/2255/27006 17 Human_papillomavirus_type_16 R-HSA-5654704 SHC-mediated cascade:FGFR3 17/4644 18/10654 7.722927586281689e-6 1.877862634931232e-5 6.6500443687402304e-6 4893/2250/2885/2253/3845/3265/8823/2249/2247/2246/6464/6654/8822/8817/2254/26281/2261 17 Human_papillomavirus_type_16 R-HSA-5654710 PI-3K cascade:FGFR3 17/4644 18/10654 7.722927586281689e-6 1.877862634931232e-5 6.6500443687402304e-6 5295/2250/2885/2253/5290/8823/2249/2247/2246/5781/2549/8822/8817/2254/26281/10818/2261 17 Human_papillomavirus_type_16 R-HSA-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 17/4644 18/10654 7.722927586281689e-6 1.877862634931232e-5 6.6500443687402304e-6 8792/10673/8740/7187/51330/958/9020/8742/959/4055/8600/330/115650/4050/7186/329/4049 17 Human_papillomavirus_type_16 R-HSA-373755 Semaphorin interactions 46/4644 65/10654 8.10980760511641e-6 1.9685225034564573e-5 6.971096684784094e-6 5361/2909/388/2064/5788/8829/3688/23365/79784/2534/9475/1808/4628/6093/10507/5362/5062/5879/27289/23396/1072/7094/389/10371/5364/3672/2932/55558/10627/4233/5063/3326/387/5058/1020/3984/4627/3985/1809/10398/4637/3320/91584/103910/8851/2242 46 Human_papillomavirus_type_16 R-HSA-382556 ABC-family proteins mediated transport 67/4644 103/10654 8.519290981581359e-6 2.064346329388367e-5 7.310436039098995e-6 5689/1965/5682/23/143471/5705/5709/5695/5711/5683/5699/6400/5702/5696/5691/7314/5718/5700/122706/5707/10956/79139/91445/23198/9861/8894/5698/215/5692/5713/5710/5719/6233/10058/1968/5243/6048/5706/335/5714/22/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/5824/7316/10213/7415/5715/5701/5825/5685/5686/5716/5693/5721 67 Human_papillomavirus_type_16 R-HSA-199977 ER to Golgi Anterograde Transport 94/4644 154/10654 8.642384992903046e-6 2.0742565016422835e-5 7.3455307707180695e-6 6811/23256/374/6711/11014/126003/51807/10484/7039/5861/10381/1780/8655/84516/832/3998/7846/9382/9632/3630/81027/6709/10652/54732/51164/1294/79861/4253/2801/10466/22872/1315/81562/8615/11316/91949/8729/10376/1314/10540/27095/378/6396/26286/1453/26958/140735/84364/22820/84617/11258/6712/2890/1783/10382/93661/55860/830/7277/10671/966/1639/81876/347733/51143/23243/5537/9871/10383/84790/7280/829/1778/9919/10113/25839/55291/63908/1604/1781/10121/2804/57511/22870/10972/381/4905/9276/287/375/64689/288/10427/372 94 Human_papillomavirus_type_16 R-HSA-1250347 SHC1 events in ERBB4 signaling 14/4644 14/10654 8.841093285688421e-6 2.0742565016422835e-5 7.3455307707180695e-6 4893/145957/9542/2885/3845/3265/1839/2069/6464/3084/6654/10718/685/2066 14 Human_papillomavirus_type_16 R-HSA-169893 Prolonged ERK activation events 14/4644 14/10654 8.841093285688421e-6 2.0742565016422835e-5 7.3455307707180695e-6 5605/1399/5594/4914/673/2889/7529/5595/5604/57498/10818/4803/1398/5906 14 Human_papillomavirus_type_16 R-HSA-174411 Polymerase switching on the C-strand of the telomere 14/4644 14/10654 8.841093285688421e-6 2.0742565016422835e-5 7.3455307707180695e-6 5982/5422/10714/5558/5557/5985/5984/23649/5424/5425/5111/5983/57804/5981 14 Human_papillomavirus_type_16 R-HSA-180336 SHC1 events in EGFR signaling 14/4644 14/10654 8.841093285688421e-6 2.0742565016422835e-5 7.3455307707180695e-6 374/4893/7039/2885/3845/3265/1839/2069/255324/6464/6654/1956/685/1950 14 Human_papillomavirus_type_16 R-HSA-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase 14/4644 14/10654 8.841093285688421e-6 2.0742565016422835e-5 7.3455307707180695e-6 107/5567/5573/5613/801/805/5568/5566/5577/5575/114/5576/1385/808 14 Human_papillomavirus_type_16 R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 14/4644 14/10654 8.841093285688421e-6 2.0742565016422835e-5 7.3455307707180695e-6 4436/9156/6117/10714/6118/3978/5424/2956/4292/5425/5111/6119/57804/5395 14 Human_papillomavirus_type_16 R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 14/4644 14/10654 8.841093285688421e-6 2.0742565016422835e-5 7.3455307707180695e-6 4436/9156/6117/10714/4437/6118/3978/5424/4292/5425/5111/6119/57804/5395 14 Human_papillomavirus_type_16 R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 14/4644 14/10654 8.841093285688421e-6 2.0742565016422835e-5 7.3455307707180695e-6 9134/57060/1869/8900/144455/898/890/7157/79733/1820/1017/25946/1027/1026 14 Human_papillomavirus_type_16 R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 14/4644 14/10654 8.841093285688421e-6 2.0742565016422835e-5 7.3455307707180695e-6 7159/51230/23368/5458/10000/7157/5457/54971/8626/208/7161/25946/207/10848 14 Human_papillomavirus_type_16 R-HSA-69091 Polymerase switching 14/4644 14/10654 8.841093285688421e-6 2.0742565016422835e-5 7.3455307707180695e-6 5982/5422/10714/5558/5557/5985/5984/23649/5424/5425/5111/5983/57804/5981 14 Human_papillomavirus_type_16 R-HSA-69109 Leading Strand Synthesis 14/4644 14/10654 8.841093285688421e-6 2.0742565016422835e-5 7.3455307707180695e-6 5982/5422/10714/5558/5557/5985/5984/23649/5424/5425/5111/5983/57804/5981 14 Human_papillomavirus_type_16 R-HSA-69166 Removal of the Flap Intermediate 14/4644 14/10654 8.841093285688421e-6 2.0742565016422835e-5 7.3455307707180695e-6 2237/1763/5422/6117/10714/5558/6118/5557/23649/5424/5425/5111/6119/57804 14 Human_papillomavirus_type_16 R-HSA-877312 Regulation of IFNG signaling 14/4644 14/10654 8.841093285688421e-6 2.0742565016422835e-5 7.3455307707180695e-6 5777/5770/9021/3459/3717/3458/5781/8554/6772/8651/5771/3716/3460/7341 14 Human_papillomavirus_type_16 R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 14/4644 14/10654 8.841093285688421e-6 2.0742565016422835e-5 7.3455307707180695e-6 4893/2909/5753/9564/3845/3265/5829/5879/5921/1793/387/63916/1398/9844 14 Human_papillomavirus_type_16 R-HSA-8941856 RUNX3 regulates NOTCH signaling 14/4644 14/10654 8.841093285688421e-6 2.0742565016422835e-5 7.3455307707180695e-6 182/22938/1387/9794/2648/55534/3280/84441/8850/864/10046/4851/2033/3516 14 Human_papillomavirus_type_16 R-HSA-8983432 Interleukin-15 signaling 14/4644 14/10654 8.841093285688421e-6 2.0742565016422835e-5 7.3455307707180695e-6 6776/2885/9846/3600/3718/6777/6464/6774/6654/3716/6655/3561/3560/3601 14 Human_papillomavirus_type_16 R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 14/4644 14/10654 8.841093285688421e-6 2.0742565016422835e-5 7.3455307707180695e-6 79718/9612/6907/4204/814/801/805/5566/25942/8841/9611/2874/3065/808 14 Human_papillomavirus_type_16 R-HSA-9005895 Pervasive developmental disorders 14/4644 14/10654 8.841093285688421e-6 2.0742565016422835e-5 7.3455307707180695e-6 79718/9612/6907/4204/814/801/805/5566/25942/8841/9611/2874/3065/808 14 Human_papillomavirus_type_16 R-HSA-4090294 SUMOylation of intracellular receptors 25/4644 30/10654 8.929464190676711e-6 2.0914921969147623e-5 7.406567257709178e-6 7068/6613/7181/9759/8856/7067/6612/5914/7421/10062/51588/2516/5465/2099/9063/8554/5241/2908/9971/7329/367/5468/4306/7341/6256 25 Human_papillomavirus_type_16 R-HSA-5696394 DNA Damage Recognition in GG-NER 30/4644 38/10654 9.117188459205917e-6 2.131902568044317e-5 7.549671846921392e-6 10445/9978/10980/10987/7314/83444/86/1643/6233/93973/8607/5886/8451/8450/1642/142/1069/2873/7311/60/8533/10038/51138/7528/9318/7316/4798/5887/50813/7508 30 Human_papillomavirus_type_16 R-HSA-381119 Unfolded Protein Response (UPR) 62/4644 94/10654 9.447897741535907e-6 2.2055574927412442e-5 7.810504832305716e-6 5393/10525/1965/2673/23404/5526/811/3576/100137049/10130/3309/4801/6347/11340/9820/10488/8720/9695/7094/9114/58477/468/22872/51726/3068/1054/8894/9451/2931/64061/8570/23016/118460/1968/1200/6464/37/5073/7184/118/1051/84447/4800/1639/10954/51010/56915/167227/22894/4000/10113/440/4802/116138/1649/2081/30827/51013/467/10106/54512/7709 62 Human_papillomavirus_type_16 R-HSA-416572 Sema4D induced cell migration and growth-cone collapse 19/4644 21/10654 9.976379042164418e-6 2.3059077094162567e-5 8.165873420448463e-6 388/2064/23365/79784/9475/4628/6093/10507/27289/389/5364/10627/387/3984/4627/3985/10398/4637/103910 19 Human_papillomavirus_type_16 R-HSA-445144 Signal transduction by L1 19/4644 21/10654 9.976379042164418e-6 2.3059077094162567e-5 8.165873420448463e-6 1459/1460/8829/4684/3688/1457/5605/3690/5879/5594/2260/7410/3685/3674/3897/1956/5058/5595/5604 19 Human_papillomavirus_type_16 R-HSA-500657 Presynaptic function of Kainate receptors 19/4644 21/10654 9.976379042164418e-6 2.3059077094162567e-5 8.165873420448463e-6 2788/5331/2782/2787/10681/2792/2785/2783/2784/2791/2899/2786/54331/59345/51764/94235/55970/2793/2790 19 Human_papillomavirus_type_16 R-HSA-5621575 CD209 (DC-SIGN) signaling 19/4644 21/10654 9.976379042164418e-6 2.3059077094162567e-5 8.165873420448463e-6 9252/4893/4790/1387/2534/5894/3845/3265/5062/5567/5970/5568/5566/4067/5063/30835/5971/5058/2033 19 Human_papillomavirus_type_16 R-HSA-5654688 SHC-mediated cascade:FGFR1 19/4644 21/10654 9.976379042164418e-6 2.3059077094162567e-5 8.165873420448463e-6 4893/2250/2885/2253/3845/3265/2260/2249/2248/2247/2246/2251/6464/6654/8822/2254/26281/2255/27006 19 Human_papillomavirus_type_16 R-HSA-5654689 PI-3K cascade:FGFR1 19/4644 21/10654 9.976379042164418e-6 2.3059077094162567e-5 8.165873420448463e-6 5295/2250/2885/2253/5290/2260/2249/2248/2247/2246/2251/5781/2549/8822/2254/26281/10818/2255/27006 19 Human_papillomavirus_type_16 R-HSA-203927 MicroRNA (miRNA) biogenesis 21/4644 24/10654 1.0587952939821508e-5 2.4352291761589467e-5 8.623837424669116e-6 5431/5435/5433/5439/192669/29102/5438/54487/57510/26523/23405/5434/5436/5901/5432/27161/5440/5430/5441/192670/5437 21 Human_papillomavirus_type_16 R-HSA-5260271 Diseases of Immune System 21/4644 24/10654 1.0587952939821508e-5 2.4352291761589467e-5 8.623837424669116e-6 4790/10333/4792/929/7187/3551/8517/5970/7096/4791/81793/7098/695/81622/23643/1147/7099/4615/7100/7097/148022 21 Human_papillomavirus_type_16 R-HSA-5602358 Diseases associated with the TLR signaling cascade 21/4644 24/10654 1.0587952939821508e-5 2.4352291761589467e-5 8.623837424669116e-6 4790/10333/4792/929/7187/3551/8517/5970/7096/4791/81793/7098/695/81622/23643/1147/7099/4615/7100/7097/148022 21 Human_papillomavirus_type_16 R-HSA-445717 Aquaporin-mediated transport 38/4644 52/10654 1.5120609734721225e-5 3.47204835643435e-5 1.2295508303537633e-5 2788/107/554/2782/2787/5567/10681/112/5573/111/2792/2785/2783/2784/196883/115/2791/5568/359/113/5566/2786/5577/109/54331/5575/59345/51764/94235/114/108/8766/55970/2778/2793/5576/551/2790 38 Human_papillomavirus_type_16 R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 56/4644 84/10654 1.5707987240020488e-5 3.60103040812888e-5 1.2752270342775492e-5 7124/1052/4790/79718/892/5469/9612/1387/6907/4023/10499/23054/7040/85441/9282/51129/7471/3952/5465/5970/6604/9439/896/9370/9412/5105/1019/9440/6721/9862/1051/1050/1024/9314/9968/2167/51586/6517/8841/5468/29079/6720/6837/688/9611/2033/9967/7026/6256/10498/112950/27332/8202/8648/1959/10891 56 Human_papillomavirus_type_16 R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 16/4644 17/10654 1.680485779358978e-5 3.82747004616988e-5 1.3554157345479114e-5 356/929/8737/841/8797/8772/8717/8743/8837/8795/23643/7186/355/7099/353376/148022 16 Human_papillomavirus_type_16 R-HSA-2033519 Activated point mutants of FGFR2 16/4644 17/10654 1.680485779358978e-5 3.82747004616988e-5 1.3554157345479114e-5 2250/2252/2253/8823/2249/2248/2247/2246/2251/2263/8822/8817/2254/26281/2255/27006 16 Human_papillomavirus_type_16 R-HSA-450513 Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA 16/4644 17/10654 1.680485779358978e-5 3.82747004616988e-5 1.3554157345479114e-5 5393/23404/11340/9261/23016/118460/3842/7538/51010/56915/167227/7529/22894/51013/54464/54512 16 Human_papillomavirus_type_16 R-HSA-9034015 Signaling by NTRK3 (TRKC) 16/4644 17/10654 1.680485779358978e-5 3.82747004616988e-5 1.3554157345479114e-5 5295/4893/5335/2885/3845/3265/5290/3667/6714/25920/4908/6464/5802/6654/4916/581 16 Human_papillomavirus_type_16 R-HSA-375280 Amine ligand-binding receptors 32/4644 42/10654 1.7277751719272378e-5 3.92879832449581e-5 1.3912989527418858e-5 1816/83551/3363/155/3354/3360/153/319100/1812/3361/134864/1129/1132/1814/3362/1813/3352/150/9287/134860/11255/3350/151/1128/9038/152/3355/3351/1815/154/3274/59340 32 Human_papillomavirus_type_16 R-HSA-110373 Resolution of AP sites via the multiple-nucleotide patch replacement pathway 22/4644 26/10654 1.983250825240395e-5 4.502428653417919e-5 1.594437726985976e-5 2237/5982/6117/10714/6118/328/3978/5985/5984/5424/54107/5425/5111/6119/5427/142/5983/10038/56655/57804/5426/5981 22 Human_papillomavirus_type_16 R-HSA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 13/4644 13/10654 2.0314850713239127e-5 4.552992899468769e-5 1.6123439610978423e-5 5925/5422/1869/28227/5518/5558/5515/7027/5557/5519/7029/23649/5516 13 Human_papillomavirus_type_16 R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 13/4644 13/10654 2.0314850713239127e-5 4.552992899468769e-5 1.6123439610978423e-5 2064/9542/7314/2065/9101/10000/6233/10193/3084/208/7311/207/7316 13 Human_papillomavirus_type_16 R-HSA-179812 GRB2 events in EGFR signaling 13/4644 13/10654 2.0314850713239127e-5 4.552992899468769e-5 1.6123439610978423e-5 374/4893/7039/2885/3845/3265/1839/2069/255324/6654/1956/685/1950 13 Human_papillomavirus_type_16 R-HSA-209543 p75NTR recruits signalling complexes 13/4644 13/10654 2.0314850713239127e-5 4.552992899468769e-5 1.6123439610978423e-5 8878/3654/3551/7314/8767/6233/7189/7311/4804/5584/4615/7316/4803 13 Human_papillomavirus_type_16 R-HSA-209560 NF-kB is activated and signals survival 13/4644 13/10654 2.0314850713239127e-5 4.552992899468769e-5 1.6123439610978423e-5 4790/8878/4792/3654/3551/7314/5970/6233/7189/7311/4804/7316/4803 13 Human_papillomavirus_type_16 R-HSA-5357786 TNFR1-induced proapoptotic signaling 13/4644 13/10654 2.0314850713239127e-5 4.552992899468769e-5 1.6123439610978423e-5 7124/7375/1540/8737/841/7128/8772/8717/27005/7186/56957/7132/9099 13 Human_papillomavirus_type_16 R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13/4644 13/10654 2.0314850713239127e-5 4.552992899468769e-5 1.6123439610978423e-5 7531/10971/7533/2810/11200/7465/7534/983/7532/891/1111/7529/995 13 Human_papillomavirus_type_16 R-HSA-8847993 ERBB2 Activates PTK6 Signaling 13/4644 13/10654 2.0314850713239127e-5 4.552992899468769e-5 1.6123439610978423e-5 2064/5753/145957/9542/1839/2065/2069/3084/10718/1956/685/1950/2066 13 Human_papillomavirus_type_16 R-HSA-167044 Signalling to RAS 18/4644 20/10654 2.0832961483206565e-5 4.6101963660786766e-5 1.6326013315745478e-5 4893/1432/5603/2885/3845/3265/9261/6714/4914/5600/6300/6464/7867/6654/5900/25759/53358/4803 18 Human_papillomavirus_type_16 R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 18/4644 20/10654 2.0832961483206565e-5 4.6101963660786766e-5 1.6326013315745478e-5 7321/7334/3551/7314/11035/8737/8517/7323/6233/330/7098/7189/7311/1147/7316/7322/329/148022 18 Human_papillomavirus_type_16 R-HSA-3232118 SUMOylation of transcription factors 18/4644 20/10654 2.0832961483206565e-5 4.6101963660786766e-5 1.6326013315745478e-5 9112/6613/7022/6612/4286/6670/51588/7157/7158/9063/8554/7020/1029/7329/7021/3090/7341/4193 18 Human_papillomavirus_type_16 R-HSA-418217 G beta:gamma signalling through PLC beta 18/4644 20/10654 2.0832961483206565e-5 4.6101963660786766e-5 1.6326013315745478e-5 2788/5331/2782/2787/10681/2792/2785/2783/2784/2791/2786/54331/59345/51764/94235/55970/2793/2790 18 Human_papillomavirus_type_16 R-HSA-5627117 RHO GTPases Activate ROCKs 18/4644 20/10654 2.0832961483206565e-5 4.6101963660786766e-5 1.6326013315745478e-5 388/79784/9475/4628/6093/1072/4659/389/5500/10627/387/5058/3984/4627/3985/10398/4637/103910 18 Human_papillomavirus_type_16 R-HSA-5654706 FRS-mediated FGFR3 signaling 18/4644 20/10654 2.0832961483206565e-5 4.6101963660786766e-5 1.6326013315745478e-5 4893/2250/2885/2253/3845/3265/8823/2249/2247/2246/5781/6654/8822/8817/2254/26281/10818/2261 18 Human_papillomavirus_type_16 R-HSA-5654719 SHC-mediated cascade:FGFR4 18/4644 20/10654 2.0832961483206565e-5 4.6101963660786766e-5 1.6326013315745478e-5 4893/9965/2264/2885/2253/3845/3265/8823/2249/2247/2246/2251/6464/6654/8822/8817/2254/26281 18 Human_papillomavirus_type_16 R-HSA-5654720 PI-3K cascade:FGFR4 18/4644 20/10654 2.0832961483206565e-5 4.6101963660786766e-5 1.6326013315745478e-5 5295/9965/2264/2885/2253/5290/8823/2249/2247/2246/2251/5781/2549/8822/8817/2254/26281/10818 18 Human_papillomavirus_type_16 R-HSA-112409 RAF-independent MAPK1/3 activation 20/4644 23/10654 2.1409471093244524e-5 4.704071987113266e-5 1.6658453523783333e-5 1844/1850/1852/5605/3717/1847/3569/3572/1849/5594/983/1843/3570/7297/5781/8682/11221/3716/5595/5604 20 Human_papillomavirus_type_16 R-HSA-438066 Unblocking of NMDA receptors, glutamate binding and activation 20/4644 23/10654 2.1409471093244524e-5 4.704071987113266e-5 1.6658453523783333e-5 817/1741/1739/1740/818/57554/2892/2902/801/2891/805/2904/2890/816/2893/815/2903/1742/88/808 20 Human_papillomavirus_type_16 R-HSA-5654693 FRS-mediated FGFR1 signaling 20/4644 23/10654 2.1409471093244524e-5 4.704071987113266e-5 1.6658453523783333e-5 4893/2250/2885/2253/3845/3265/2260/2249/2248/2247/2246/2251/5781/6654/8822/2254/26281/10818/2255/27006 20 Human_papillomavirus_type_16 R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 27/4644 34/10654 2.1424818244942102e-5 4.704071987113266e-5 1.6658453523783333e-5 5431/5435/5433/5439/11198/904/51497/5438/1025/7936/6829/25920/2963/5434/5436/2962/5432/6917/5440/5430/6749/5441/7469/9150/5437/6827/8178 27 Human_papillomavirus_type_16 R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 27/4644 34/10654 2.1424818244942102e-5 4.704071987113266e-5 1.6658453523783333e-5 5431/5435/5433/5439/11198/904/51497/5438/1025/7936/6829/25920/2963/5434/5436/2962/5432/6917/5440/5430/6749/5441/7469/9150/5437/6827/8178 27 Human_papillomavirus_type_16 R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 30/4644 39/10654 2.3008181605892095e-5 5.035956129963589e-5 1.7833749434241018e-5 9134/10528/10576/10574/54461/10693/10575/898/26985/26190/10238/7157/26224/2629/8237/6774/26272/26270/55135/22948/10694/8841/22803/7203/908/11328/6950/3801/55294/6499 30 Human_papillomavirus_type_16 R-HSA-73933 Resolution of Abasic Sites (AP sites) 30/4644 39/10654 2.3008181605892095e-5 5.035956129963589e-5 1.7833749434241018e-5 2237/4913/5982/6117/10714/6118/328/3978/5985/5984/4595/5424/7515/54107/5425/5111/6119/5427/142/4968/3980/5983/10038/56655/11284/57804/6996/5426/8930/5981 30 Human_papillomavirus_type_16 R-HSA-5654687 Downstream signaling of activated FGFR1 25/4644 31/10654 2.6962330913599176e-5 5.8922352448254896e-5 2.0866076719493053e-5 5295/4893/2250/5335/2885/2253/3845/3265/5290/2260/2249/2248/2247/2246/2251/5781/6464/6654/2549/8822/2254/26281/10818/2255/27006 25 Human_papillomavirus_type_16 R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 28/4644 36/10654 3.0328313729442546e-5 6.617515421836374e-5 2.3434499599405557e-5 4893/71/5908/5605/3690/408/5894/8826/4140/3845/3265/8844/7094/5594/7414/6714/2335/1445/369/283455/3674/409/673/60/7529/5595/5604/5906 28 Human_papillomavirus_type_16 R-HSA-9609736 Assembly and cell surface presentation of NMDA receptors 31/4644 41/10654 3.0550902406643636e-5 6.655732310018791e-5 2.3569836443177177e-5 51807/817/10381/7846/81027/1741/1739/1740/8825/818/57554/79861/2902/10376/84617/320/8573/2904/10382/7277/55327/347733/816/10383/84790/7280/64130/815/2903/1742/88 31 Human_papillomavirus_type_16 R-HSA-422356 Regulation of insulin secretion 52/4644 78/10654 3.138778322878648e-5 6.82745114263371e-5 2.4177941548734747e-5 2788/5331/2740/2770/5578/2769/9495/2782/3630/8826/2181/6513/2787/5567/10681/112/5573/111/2792/2785/2783/2784/2771/6844/2182/2791/5568/150/6616/5566/2641/6514/2786/5577/54331/5575/59345/51764/94235/114/4082/3790/55970/2778/2767/10768/152/2793/5576/5906/9630/2790 52 Human_papillomavirus_type_16 R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 23/4644 28/10654 3.300447760552425e-5 7.168000322066645e-5 2.5383922812135325e-5 2788/2770/2782/2787/10681/112/111/2792/2785/2783/2784/2771/2791/150/2786/54331/59345/51764/94235/55970/152/2793/2790 23 Human_papillomavirus_type_16 R-HSA-1295596 Spry regulation of FGF signaling 15/4644 16/10654 3.644665396151072e-5 7.854785792319438e-5 2.7816025013878345e-5 2885/5518/7314/5515/5594/6714/6233/5781/673/7311/5595/5516/10253/7316/867 15 Human_papillomavirus_type_16 R-HSA-1433559 Regulation of KIT signaling 15/4644 16/10654 3.644665396151072e-5 7.854785792319438e-5 2.7816025013878345e-5 5777/5578/2534/2885/3815/9306/6714/7525/3932/10019/8651/4067/6654/867/4254 15 Human_papillomavirus_type_16 R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 15/4644 16/10654 3.644665396151072e-5 7.854785792319438e-5 2.7816025013878345e-5 5295/5291/2534/2885/9846/5290/5170/6464/2205/2206/6850/4067/6654/5296/2207 15 Human_papillomavirus_type_16 R-HSA-429958 mRNA decay by 3' to 5' exoribonuclease 15/4644 16/10654 3.644665396151072e-5 7.854785792319438e-5 2.7816025013878345e-5 5393/23404/28960/10767/11340/80349/23016/118460/9652/51010/56915/22894/51013/6499/54512 15 Human_papillomavirus_type_16 R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 15/4644 16/10654 3.644665396151072e-5 7.854785792319438e-5 2.7816025013878345e-5 929/7314/257397/23118/10454/6233/3656/7189/7311/23643/6885/7099/7316/353376/148022 15 Human_papillomavirus_type_16 R-HSA-937041 IKK complex recruitment mediated by RIP1 21/4644 25/10654 3.883180991522784e-5 8.343189787299337e-5 2.9545602127810983e-5 7321/929/7334/3551/7314/11035/8737/8517/7323/6233/330/7189/7311/23643/1147/7099/7316/7322/329/353376/148022 21 Human_papillomavirus_type_16 R-HSA-9620244 Long-term potentiation 21/4644 25/10654 3.883180991522784e-5 8.343189787299337e-5 2.9545602127810983e-5 817/1741/1739/1740/818/57554/2902/6714/801/2891/805/2904/2890/3084/816/815/2903/2066/1742/88/808 21 Human_papillomavirus_type_16 R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 29/4644 38/10654 4.107098764560232e-5 8.810794444461781e-5 3.120152288544068e-5 7039/51741/2064/5308/4609/1387/7913/1081/7022/8089/3815/348/2099/3329/10765/7020/4869/4839/10370/7329/29028/1956/7528/4605/7021/7422/1026/7341/2033 29 Human_papillomavirus_type_16 R-HSA-442982 Ras activation upon Ca2+ influx through NMDA receptor 19/4644 22/10654 4.303928251304082e-5 9.204895330151871e-5 3.259714593413875e-5 4893/817/1741/1739/1740/3845/3265/5923/818/57554/2902/801/805/2904/816/815/1742/88/808 19 Human_papillomavirus_type_16 R-HSA-5654712 FRS-mediated FGFR4 signaling 19/4644 22/10654 4.303928251304082e-5 9.204895330151871e-5 3.259714593413875e-5 4893/9965/2264/2885/2253/3845/3265/8823/2249/2247/2246/2251/5781/6654/8822/8817/2254/26281/10818 19 Human_papillomavirus_type_16 R-HSA-110320 Translesion Synthesis by POLH 17/4644 19/10654 4.328898221159196e-5 9.2442073124602e-5 3.273636081690524e-5 5982/25898/6117/55666/7314/6118/5985/5984/6233/5111/6119/5429/7311/5983/7316/7415/5981 17 Human_papillomavirus_type_16 R-HSA-111932 CaMK IV-mediated phosphorylation of CREB 12/4644 12/10654 4.667328179842195e-5 9.788133686574888e-5 3.466255842790522e-5 817/814/818/801/805/3838/10645/84254/816/815/1385/808 12 Human_papillomavirus_type_16 R-HSA-170968 Frs2-mediated activation 12/4644 12/10654 4.667328179842195e-5 9.788133686574888e-5 3.466255842790522e-5 5605/1399/5594/4914/673/2889/7529/5595/5604/10818/4803/5906 12 Human_papillomavirus_type_16 R-HSA-176974 Unwinding of DNA 12/4644 12/10654 4.667328179842195e-5 9.788133686574888e-5 3.466255842790522e-5 4174/84515/84296/64785/4175/4172/8318/4173/51659/4176/9837/4171 12 Human_papillomavirus_type_16 R-HSA-190873 Gap junction degradation 12/4644 12/10654 4.667328179842195e-5 9.788133686574888e-5 3.466255842790522e-5 71/1212/1785/2697/1759/4646/1601/1213/1211/1173/8218/60 12 Human_papillomavirus_type_16 R-HSA-389359 CD28 dependent Vav1 pathway 12/4644 12/10654 4.667328179842195e-5 9.788133686574888e-5 3.466255842790522e-5 941/2534/2885/5062/5879/7409/3932/940/5063/998/5058/942 12 Human_papillomavirus_type_16 R-HSA-451306 Ionotropic activity of kainate receptors 12/4644 12/10654 4.667328179842195e-5 9.788133686574888e-5 3.466255842790522e-5 2900/2898/1741/1739/2897/2901/83988/801/805/2899/1742/808 12 Human_papillomavirus_type_16 R-HSA-451308 Activation of Ca-permeable Kainate Receptor 12/4644 12/10654 4.667328179842195e-5 9.788133686574888e-5 3.466255842790522e-5 2900/2898/1741/1739/2897/2901/83988/801/805/2899/1742/808 12 Human_papillomavirus_type_16 R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 12/4644 12/10654 4.667328179842195e-5 9.788133686574888e-5 3.466255842790522e-5 834/55367/472/8738/7157/839/317/843/8626/7161/835/58484 12 Human_papillomavirus_type_16 R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 12/4644 12/10654 4.667328179842195e-5 9.788133686574888e-5 3.466255842790522e-5 7159/23368/8797/7157/8626/7161/8795/8793/3486/355/8794/124446 12 Human_papillomavirus_type_16 R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 12/4644 12/10654 4.667328179842195e-5 9.788133686574888e-5 3.466255842790522e-5 7187/7314/29110/3661/6233/10010/3665/7098/7311/9641/7316/148022 12 Human_papillomavirus_type_16 R-HSA-9020558 Interleukin-2 signaling 12/4644 12/10654 4.667328179842195e-5 9.788133686574888e-5 3.466255842790522e-5 6776/3558/3718/3932/6777/6464/6850/3716/2185/3561/3560/3559 12 Human_papillomavirus_type_16 R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12/4644 12/10654 4.667328179842195e-5 9.788133686574888e-5 3.466255842790522e-5 64135/3551/8737/841/8517/23586/84282/8772/7706/843/1147/57506 12 Human_papillomavirus_type_16 R-HSA-383280 Nuclear Receptor transcription pathway 37/4644 52/10654 5.1678450774407244e-5 1.0821621856193039e-4 3.832243325297757e-5 7068/5915/6097/7181/5469/9612/8856/7067/5914/8431/7421/10062/7025/2516/5465/2099/7101/5467/2103/6257/5241/7182/3172/2063/9970/2908/9971/367/5468/2100/4306/9611/3164/6256/6258/5916/9975 37 Human_papillomavirus_type_16 R-HSA-3000170 Syndecan interactions 22/4644 27/10654 6.280725535944412e-5 1.3112883819836325e-4 4.64364419324211e-5 5578/1289/7448/3688/1290/3690/87/6382/7040/3655/2247/2335/3685/9672/3691/8573/1277/3371/6383/1281/7057/1278 22 Human_papillomavirus_type_16 R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 22/4644 27/10654 6.280725535944412e-5 1.3112883819836325e-4 4.64364419324211e-5 356/836/929/26060/1612/8737/841/8797/1613/8772/8717/8743/8837/8795/23643/7186/842/355/7099/23604/353376/148022 22 Human_papillomavirus_type_16 R-HSA-1251985 Nuclear signaling by ERBB4 25/4644 32/10654 7.20982124366719e-5 1.500798101612028e-4 5.3147518772620874e-5 2670/51741/23385/6776/10413/145957/6868/9542/6387/1839/2069/23118/348/6714/2099/1447/3925/5663/5241/3084/10718/685/9611/2066/6285 25 Human_papillomavirus_type_16 R-HSA-2173789 TGF-beta receptor signaling activates SMADs 25/4644 32/10654 7.20982124366719e-5 1.500798101612028e-4 5.3147518772620874e-5 4738/4089/23327/4088/5499/7040/7314/4092/11171/7046/9958/9040/6233/7514/5500/5501/4087/7048/7311/57154/51377/10273/64750/7316/867 25 Human_papillomavirus_type_16 R-HSA-3371571 HSF1-dependent transactivation 20/4644 24/10654 7.551706186036026e-5 1.5673141684923884e-4 5.550304141714427e-5 817/3305/1387/2475/3306/3312/818/3303/3337/3297/57521/1410/816/3326/3304/10728/815/3320/2033/2288 20 Human_papillomavirus_type_16 R-HSA-933542 TRAF6 mediated NF-kB activation 20/4644 24/10654 7.551706186036026e-5 1.5673141684923884e-4 5.550304141714427e-5 4790/4792/64135/3551/4214/8517/5970/23586/84282/4791/351/7706/7189/1147/7186/57506/4793/3146/6288/6285 20 Human_papillomavirus_type_16 R-HSA-5619115 Disorders of transmembrane transporters 102/4644 176/10654 7.847767342856949e-5 1.6177746159818743e-4 5.7289989026780565e-5 23165/5689/5682/6559/285195/348995/143471/57122/5705/23511/5709/5695/554/6523/23279/5711/23225/5683/5699/6400/5702/6531/9972/8021/55746/5696/5691/6513/11136/7314/5718/5700/122706/5707/10956/79139/91445/23198/10762/9861/79902/9883/5698/215/5692/5713/5710/5719/6233/6396/129401/10058/4928/5903/55706/7175/6048/5706/19/335/5714/4927/5688/5687/5708/8086/6514/5704/7311/11160/5694/9197/81929/5684/5720/9631/5690/5717/9491/1080/79023/23636/10197/7316/10213/53371/3098/9688/7415/6519/5715/5701/5685/682/5686/6520/5716/213/5693/551/5721/8480 102 Human_papillomavirus_type_16 R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 14/4644 15/10654 7.87555283475139e-5 1.6177746159818743e-4 5.7289989026780565e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/5527 14 Human_papillomavirus_type_16 R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 14/4644 15/10654 7.87555283475139e-5 1.6177746159818743e-4 5.7289989026780565e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/5527 14 Human_papillomavirus_type_16 R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 14/4644 15/10654 7.87555283475139e-5 1.6177746159818743e-4 5.7289989026780565e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/5527 14 Human_papillomavirus_type_16 R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 14/4644 15/10654 7.87555283475139e-5 1.6177746159818743e-4 5.7289989026780565e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/5527 14 Human_papillomavirus_type_16 R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 14/4644 15/10654 7.87555283475139e-5 1.6177746159818743e-4 5.7289989026780565e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/5527 14 Human_papillomavirus_type_16 R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 14/4644 15/10654 7.87555283475139e-5 1.6177746159818743e-4 5.7289989026780565e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/5527 14 Human_papillomavirus_type_16 R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 18/4644 21/10654 8.597245612945984e-5 1.7634408764566106e-4 6.244844458772708e-5 4790/4792/1660/3551/11035/8737/29110/8517/5970/3661/4791/23220/7098/1147/147945/4615/4793/148022 18 Human_papillomavirus_type_16 R-HSA-111471 Apoptotic factor-mediated response 16/4644 18/10654 8.9460299452055e-5 1.8216661847784204e-4 6.45103679495378e-5 55075/836/840/578/5594/22900/708/331/57099/317/1029/56616/5595/842/54205/581 16 Human_papillomavirus_type_16 R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 16/4644 18/10654 8.9460299452055e-5 1.8216661847784204e-4 6.45103679495378e-5 5295/11052/613/6776/11064/2885/9846/7750/8805/5290/399687/6777/1523/9208/6774/6772 16 Human_papillomavirus_type_16 R-HSA-210993 Tie2 Signaling 16/4644 18/10654 8.9460299452055e-5 1.8216661847784204e-4 6.45103679495378e-5 5295/4893/5291/2885/3845/3265/5290/5781/6464/2888/2886/6654/285/5296/284/9046 16 Human_papillomavirus_type_16 R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 16/4644 18/10654 8.9460299452055e-5 1.8216661847784204e-4 6.45103679495378e-5 4893/5578/2885/6196/6197/3845/3265/1839/5594/5598/6195/6654/1956/5595/4314/1385 16 Human_papillomavirus_type_16 R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 16/4644 18/10654 8.9460299452055e-5 1.8216661847784204e-4 6.45103679495378e-5 929/7187/7314/29110/3661/6233/10010/5781/3665/7311/9641/23643/7099/7316/353376/148022 16 Human_papillomavirus_type_16 R-HSA-1059683 Interleukin-6 signaling 11/4644 11/10654 1.0721859231180788e-4 2.1428445158613456e-4 7.588420388540009e-5 9021/3717/3569/3572/3570/7297/5781/6774/6772/3716/867 11 Human_papillomavirus_type_16 R-HSA-174414 Processive synthesis on the C-strand of the telomere 11/4644 11/10654 1.0721859231180788e-4 2.1428445158613456e-4 7.588420388540009e-5 2237/1763/6117/10714/6118/3978/5424/5425/5111/6119/57804 11 Human_papillomavirus_type_16 R-HSA-196025 Formation of annular gap junctions 11/4644 11/10654 1.0721859231180788e-4 2.1428445158613456e-4 7.588420388540009e-5 71/1212/1785/2697/1759/1601/1213/1211/1173/8218/60 11 Human_papillomavirus_type_16 R-HSA-2514853 Condensation of Prometaphase Chromosomes 11/4644 11/10654 1.0721859231180788e-4 2.1428445158613456e-4 7.588420388540009e-5 1459/1460/1457/64151/10051/983/23397/9133/891/10592/9918 11 Human_papillomavirus_type_16 R-HSA-2586552 Signaling by Leptin 11/4644 11/10654 1.0721859231180788e-4 2.1428445158613456e-4 7.588420388540009e-5 3953/9021/6776/3717/8660/3667/3952/6777/5781/6774/25970 11 Human_papillomavirus_type_16 R-HSA-3371378 Regulation by c-FLIP 11/4644 11/10654 1.0721859231180788e-4 2.1428445158613456e-4 7.588420388540009e-5 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355 11 Human_papillomavirus_type_16 R-HSA-5218900 CASP8 activity is inhibited 11/4644 11/10654 1.0721859231180788e-4 2.1428445158613456e-4 7.588420388540009e-5 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355 11 Human_papillomavirus_type_16 R-HSA-5655291 Signaling by FGFR4 in disease 11/4644 11/10654 1.0721859231180788e-4 2.1428445158613456e-4 7.588420388540009e-5 5295/4893/5335/2264/2885/3845/3265/5290/6654/2549/10818 11 Human_papillomavirus_type_16 R-HSA-68689 CDC6 association with the ORC:origin complex 11/4644 11/10654 1.0721859231180788e-4 2.1428445158613456e-4 7.588420388540009e-5 1869/84515/4998/990/5001/23594/4999/5000/1870/23595/1871 11 Human_papillomavirus_type_16 R-HSA-69416 Dimerization of procaspase-8 11/4644 11/10654 1.0721859231180788e-4 2.1428445158613456e-4 7.588420388540009e-5 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355 11 Human_papillomavirus_type_16 R-HSA-8875555 MET activates RAP1 and RAC1 11/4644 11/10654 1.0721859231180788e-4 2.1428445158613456e-4 7.588420388540009e-5 5908/3082/2885/1399/5879/85440/4233/2889/2549/1398/5906 11 Human_papillomavirus_type_16 R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 11/4644 11/10654 1.0721859231180788e-4 2.1428445158613456e-4 7.588420388540009e-5 7314/257397/23118/10454/6233/7098/7189/7311/6885/7316/148022 11 Human_papillomavirus_type_16 R-HSA-9614399 Regulation of localization of FOXO transcription factors 11/4644 11/10654 1.0721859231180788e-4 2.1428445158613456e-4 7.588420388540009e-5 2308/10971/2810/7534/10000/7532/4303/208/7529/2309/207 11 Human_papillomavirus_type_16 R-HSA-180024 DARPP-32 events 21/4644 26/10654 1.1862887689908922e-4 2.3641521916111104e-4 8.372133656753905e-5 5530/5499/5518/5515/5567/5573/5528/5519/801/805/5568/5566/5577/1020/5516/5575/5532/5576/5534/5144/808 21 Human_papillomavirus_type_16 R-HSA-2173788 Downregulation of TGF-beta receptor signaling 21/4644 26/10654 1.1862887689908922e-4 2.3641521916111104e-4 8.372133656753905e-5 23327/4088/5499/7040/7314/4092/11171/7046/9958/6233/7514/5500/5501/4087/7048/7311/57154/51377/10273/64750/7316 21 Human_papillomavirus_type_16 R-HSA-9617324 Negative regulation of NMDA receptor-mediated neuronal transmission 19/4644 23/10654 1.4578088675707318e-4 2.901143037165584e-4 1.0273770593406277e-4 817/1741/1739/1740/814/818/57554/2902/801/805/2904/816/815/2903/9647/1742/88/808/8536 19 Human_papillomavirus_type_16 R-HSA-162594 Early Phase of HIV Life Cycle 13/4644 14/10654 1.694736972713984e-4 3.306976318105312e-4 1.1710941382343905e-4 2237/7852/3981/3836/7518/3978/5478/920/2547/1234/3159/7520/8815 13 Human_papillomavirus_type_16 R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 13/4644 14/10654 1.694736972713984e-4 3.306976318105312e-4 1.1710941382343905e-4 5861/2801/5594/983/8615/9133/891/81876/5347/5595/5862/26003/64689 13 Human_papillomavirus_type_16 R-HSA-170670 Adenylate cyclase inhibitory pathway 13/4644 14/10654 1.694736972713984e-4 3.306976318105312e-4 1.1710941382343905e-4 2770/107/2773/112/111/2771/196883/115/113/109/114/108/346562 13 Human_papillomavirus_type_16 R-HSA-177504 Retrograde neurotrophin signalling 13/4644 14/10654 1.694736972713984e-4 3.306976318105312e-4 1.1710941382343905e-4 1785/6456/163/1759/161/4914/1213/1211/1175/1173/160/26052/4803 13 Human_papillomavirus_type_16 R-HSA-3371568 Attenuation phase 13/4644 14/10654 1.694736972713984e-4 3.306976318105312e-4 1.1710941382343905e-4 3305/1387/3306/3312/3303/3337/3297/3326/3304/10728/3320/2033/2288 13 Human_papillomavirus_type_16 R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 13/4644 14/10654 1.694736972713984e-4 3.306976318105312e-4 1.1710941382343905e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/5527 13 Human_papillomavirus_type_16 R-HSA-4839744 truncated APC mutants destabilize the destruction complex 13/4644 14/10654 1.694736972713984e-4 3.306976318105312e-4 1.1710941382343905e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/5527 13 Human_papillomavirus_type_16 R-HSA-4839748 AMER1 mutants destabilize the destruction complex 13/4644 14/10654 1.694736972713984e-4 3.306976318105312e-4 1.1710941382343905e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/5527 13 Human_papillomavirus_type_16 R-HSA-5467337 APC truncation mutants have impaired AXIN binding 13/4644 14/10654 1.694736972713984e-4 3.306976318105312e-4 1.1710941382343905e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/5527 13 Human_papillomavirus_type_16 R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 13/4644 14/10654 1.694736972713984e-4 3.306976318105312e-4 1.1710941382343905e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/5527 13 Human_papillomavirus_type_16 R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 13/4644 14/10654 1.694736972713984e-4 3.306976318105312e-4 1.1710941382343905e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/5527 13 Human_papillomavirus_type_16 R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 13/4644 14/10654 1.694736972713984e-4 3.306976318105312e-4 1.1710941382343905e-4 79370/7159/23368/332/64065/7157/604/5875/8626/7161/10397/9540/5876 13 Human_papillomavirus_type_16 R-HSA-9027284 Erythropoietin activates RAS 13/4644 14/10654 1.694736972713984e-4 3.306976318105312e-4 1.1710941382343905e-4 4893/3717/2885/2056/8660/3845/3265/1399/7409/6464/2889/4067/6654 13 Human_papillomavirus_type_16 R-HSA-918233 TRAF3-dependent IRF activation pathway 13/4644 14/10654 1.694736972713984e-4 3.306976318105312e-4 1.1710941382343905e-4 1387/64135/7187/29110/23586/3661/84282/3665/7706/9641/3456/57506/2033 13 Human_papillomavirus_type_16 R-HSA-5625900 RHO GTPases activate CIT 17/4644 20/10654 1.7053976633910813e-4 3.3231568357467876e-4 1.1768241185973545e-4 388/79784/4628/5879/4659/389/9055/5500/10627/387/4627/1027/10398/4637/1742/9928/103910 17 Human_papillomavirus_type_16 R-HSA-416993 Trafficking of GluR2-containing AMPA receptors 15/4644 17/10654 1.8376012522091582e-4 3.556075250826826e-4 1.2593071376300875e-4 5579/23426/5578/5582/9463/163/161/2892/1175/2891/1173/2890/160/2893/4905 15 Human_papillomavirus_type_16 R-HSA-450385 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA 15/4644 17/10654 1.8376012522091582e-4 3.556075250826826e-4 1.2593071376300875e-4 5393/23404/11340/9261/23016/118460/51010/56915/167227/7529/22894/207/51013/54464/54512 15 Human_papillomavirus_type_16 R-HSA-4655427 SUMOylation of DNA methylation proteins 15/4644 17/10654 1.8376012522091582e-4 3.556075250826826e-4 1.2593071376300875e-4 1912/6045/80012/1911/1789/57332/1788/84733/7703/6015/8535/1786/7329/648/7341 15 Human_papillomavirus_type_16 R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 15/4644 17/10654 1.8376012522091582e-4 3.556075250826826e-4 1.2593071376300875e-4 929/7314/257397/23118/10454/6233/3656/7189/7311/23643/6885/7099/7316/353376/148022 15 Human_papillomavirus_type_16 R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 15/4644 17/10654 1.8376012522091582e-4 3.556075250826826e-4 1.2593071376300875e-4 2308/857/2290/57060/4089/1647/4088/5934/4303/901/9314/4087/2309/1027/1026 15 Human_papillomavirus_type_16 R-HSA-5674135 MAP2K and MAPK activation 29/4644 40/10654 1.9842824765934958e-4 3.82936494451262e-4 1.3560867718122495e-4 4893/71/84292/5908/5605/3690/408/5894/8826/4140/3845/3265/8844/7094/5594/7414/6714/2335/1445/369/283455/3674/409/673/60/7529/5595/5604/5906 29 Human_papillomavirus_type_16 R-HSA-6783310 Fanconi Anemia Pathway 29/4644 40/10654 1.9842824765934958e-4 3.82936494451262e-4 1.3560867718122495e-4 80198/84126/57599/2067/6117/7314/6118/2176/197342/84464/2177/29089/6233/2188/57697/6119/55215/146956/7311/2175/2178/545/2072/7316/9937/7398/2189/55120/2187 29 Human_papillomavirus_type_16 R-HSA-373080 Class B/2 (Secretin family receptors) 59/4644 95/10654 2.0237737678442428e-4 3.9002123575349897e-4 1.3811758508133065e-4 2788/2692/2740/2696/117/799/5741/2782/10267/6469/2787/7476/133/8322/10681/7471/5727/2792/5744/2785/2783/2784/7474/2791/10268/6343/9340/116/6344/2642/79924/2641/1392/2786/113091/7432/54331/59345/6608/7433/10266/5745/51764/94235/2695/5746/1604/796/55970/2778/2691/2793/797/7434/10203/3375/1395/1394/2790 59 Human_papillomavirus_type_16 R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 38/4644 56/10654 2.0656645190581451e-4 3.975483292508337e-4 1.4078314244393106e-4 79718/5469/1387/6907/10499/23054/1386/85441/3054/7019/814/23408/5465/64784/4208/6604/6742/801/805/5442/3418/23410/4209/2553/2551/6648/23373/8841/200186/9611/23409/54205/6256/10498/1385/808/8648/10891 38 Human_papillomavirus_type_16 R-HSA-429947 Deadenylation of mRNA 20/4644 25/10654 2.222580696408904e-4 4.2541346753911216e-4 1.5065097848854784e-4 26986/25904/1973/55571/57472/85456/29883/1981/1977/9924/5073/4850/246175/4848/23019/1975/1974/4849/9337/9775 20 Human_papillomavirus_type_16 R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 20/4644 25/10654 2.222580696408904e-4 4.2541346753911216e-4 1.5065097848854784e-4 2308/2475/7249/2932/10000/2931/5170/4303/6199/208/79109/1147/2309/842/207/1027/1026/3164/1385/4193 20 Human_papillomavirus_type_16 R-HSA-8854691 Interleukin-20 family signaling 20/4644 25/10654 2.222580696408904e-4 4.2541346753911216e-4 1.5065097848854784e-4 11009/6776/3717/3588/3718/6777/6773/7297/5781/6775/50616/53833/6774/6772/29949/116379/163702/3716/58985/53832 20 Human_papillomavirus_type_16 R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 20/4644 25/10654 2.222580696408904e-4 4.2541346753911216e-4 1.5065097848854784e-4 22938/1387/9794/9787/23286/2648/55534/3280/84441/4854/10320/8850/5087/10046/6772/23493/4851/23462/2033/3516 20 Human_papillomavirus_type_16 R-HSA-9012852 Signaling by NOTCH3 34/4644 49/10654 2.2896224135989556e-4 4.3764853491544067e-4 1.5498376297414415e-4 4904/182/23385/11060/22938/1387/9794/9787/7314/23286/2648/55534/3280/84441/4854/102/10320/8850/5087/6233/5663/142678/10460/10046/6772/23493/7311/1956/4851/23462/7316/1950/2033/3516 34 Human_papillomavirus_type_16 R-HSA-3928663 EPHA-mediated growth cone collapse 23/4644 30/10654 2.3512357017853257e-4 4.488141074292261e-4 1.5893780898570335e-4 2042/79784/2534/9475/4628/6093/2041/6714/1943/2043/7525/1942/10627/1945/4067/387/4627/10398/4637/1946/103910/1944/1969 23 Human_papillomavirus_type_16 R-HSA-110056 MAPK3 (ERK1) activation 10/4644 10/10654 2.462742116026936e-4 4.6192876855425015e-4 1.6358208257313733e-4 3717/3569/3572/983/3570/7297/5781/3716/5595/5604 10 Human_papillomavirus_type_16 R-HSA-1250342 PI3K events in ERBB4 signaling 10/4644 10/10654 2.462742116026936e-4 4.6192876855425015e-4 1.6358208257313733e-4 5295/145957/9542/1839/5290/2069/3084/10718/685/2066 10 Human_papillomavirus_type_16 R-HSA-174437 Removal of the Flap Intermediate from the C-strand 10/4644 10/10654 2.462742116026936e-4 4.6192876855425015e-4 1.6358208257313733e-4 2237/1763/6117/10714/6118/5424/5425/5111/6119/57804 10 Human_papillomavirus_type_16 R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 10/4644 10/10654 2.462742116026936e-4 4.6192876855425015e-4 1.6358208257313733e-4 5563/53632/1432/51422/5600/6300/5571/5564/5565/10891 10 Human_papillomavirus_type_16 R-HSA-2465910 MASTL Facilitates Mitotic Progression 10/4644 10/10654 2.462742116026936e-4 4.6192876855425015e-4 1.6358208257313733e-4 5518/55844/84930/5515/983/5519/2029/891/5516/10776 10 Human_papillomavirus_type_16 R-HSA-390450 Folding of actin by CCT/TriC 10/4644 10/10654 2.462742116026936e-4 4.6192876855425015e-4 1.6358208257313733e-4 10576/10574/10693/10575/60/22948/10694/7203/908/6950 10 Human_papillomavirus_type_16 R-HSA-419812 Calcitonin-like ligand receptors 10/4644 10/10654 2.462742116026936e-4 4.6192876855425015e-4 1.6358208257313733e-4 799/10267/133/10268/79924/10266/796/797/10203/3375 10 Human_papillomavirus_type_16 R-HSA-442729 CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde 10/4644 10/10654 2.462742116026936e-4 4.6192876855425015e-4 1.6358208257313733e-4 814/818/801/805/3838/10645/84254/816/1385/808 10 Human_papillomavirus_type_16 R-HSA-450341 Activation of the AP-1 family of transcription factors 10/4644 10/10654 2.462742116026936e-4 4.6192876855425015e-4 1.6358208257313733e-4 3725/1432/1386/5601/5594/2353/5600/5602/5595/5599 10 Human_papillomavirus_type_16 R-HSA-8853334 Signaling by FGFR3 fusions in cancer 10/4644 10/10654 2.462742116026936e-4 4.6192876855425015e-4 1.6358208257313733e-4 5295/4893/2885/3845/3265/5290/6654/2549/10818/2261 10 Human_papillomavirus_type_16 R-HSA-9020958 Interleukin-21 signaling 10/4644 10/10654 2.462742116026936e-4 4.6192876855425015e-4 1.6358208257313733e-4 6776/50615/3718/6777/59067/6775/6774/6772/3716/3561 10 Human_papillomavirus_type_16 R-HSA-937042 IRAK2 mediated activation of TAK1 complex 10/4644 10/10654 2.462742116026936e-4 4.6192876855425015e-4 1.6358208257313733e-4 7314/257397/23118/10454/6233/3656/7189/7311/6885/7316 10 Human_papillomavirus_type_16 R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 10/4644 10/10654 2.462742116026936e-4 4.6192876855425015e-4 1.6358208257313733e-4 2308/7295/1387/10628/23411/8850/4303/23410/2309/2033 10 Human_papillomavirus_type_16 R-HSA-389357 CD28 dependent PI3K/Akt signaling 18/4644 22/10654 2.791717374033448e-4 5.22934509448455e-4 1.851859462502688e-4 5295/941/2534/2475/1326/5290/57761/9020/10000/3932/940/5170/8503/208/79109/207/942/5296 18 Human_papillomavirus_type_16 R-HSA-201681 TCF dependent signaling in response to WNT 128/4644 233/10654 2.82422930681838e-4 5.28319162328825e-4 1.8709280460607375e-4 27123/9070/5689/857/5682/1459/5526/1452/5929/1460/143471/5705/6657/8452/55366/5709/9978/5695/1457/4609/5711/1387/5683/324/5699/8312/5702/1855/6932/90780/5518/25776/6659/5696/5691/7314/5515/5718/51176/8945/6662/5700/122706/5707/1856/1454/8322/23198/9101/7471/7534/5528/7091/83439/9861/5519/2932/5698/5692/5713/5710/5719/6233/7474/1857/7514/7089/331/8607/6658/4221/123169/7090/6597/864/79577/283149/5706/8658/5714/6934/10524/5688/5687/607/5708/51339/5529/7088/208/57680/5704/7311/5694/55553/5516/5684/8295/5720/7015/1487/1499/5525/207/8085/5690/5717/9491/10197/64750/7316/10213/5715/5701/1455/5685/5686/2033/54894/3065/5527/5716/23072/26108/9736/5693/5721/6259 128 Human_papillomavirus_type_16 R-HSA-5693607 Processing of DNA double-strand break ends 60/4644 98/10654 3.137787644751782e-4 5.86193883566811e-4 2.075878853911054e-4 83990/151987/9156/1763/7486/5982/472/6613/4683/165918/84126/8900/8924/672/6117/7334/83695/7314/6118/51588/51720/63967/5531/116028/890/9656/5985/5984/6233/7158/6047/5884/5810/80010/580/11073/641/6119/3364/10524/144715/1111/7329/7311/5983/1017/54962/5883/10111/51548/545/7336/29086/7316/7341/8914/5932/9025/79184/7156 60 Human_papillomavirus_type_16 R-HSA-111461 Cytochrome c-mediated apoptotic response 12/4644 13/10654 3.6297445482061646e-4 6.754020691158156e-4 2.3917903486713802e-4 55075/836/840/5594/22900/331/57099/317/56616/5595/842/54205 12 Human_papillomavirus_type_16 R-HSA-190375 FGFR2c ligand binding and activation 12/4644 13/10654 3.6297445482061646e-4 6.754020691158156e-4 2.3917903486713802e-4 2250/2253/8823/2249/2247/2246/2251/2263/8822/8817/2254/26281 12 Human_papillomavirus_type_16 R-HSA-5654227 Phospholipase C-mediated cascade; FGFR3 12/4644 13/10654 3.6297445482061646e-4 6.754020691158156e-4 2.3917903486713802e-4 2250/5335/2253/8823/2249/2247/2246/8822/8817/2254/26281/2261 12 Human_papillomavirus_type_16 R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 14/4644 16/10654 3.749176490495378e-4 6.957797111329386e-4 2.4639533605037855e-4 7040/7314/50848/7046/6233/57530/5590/7048/7311/387/57154/50855/7316/56288 14 Human_papillomavirus_type_16 R-HSA-5654219 Phospholipase C-mediated cascade: FGFR1 14/4644 16/10654 3.749176490495378e-4 6.957797111329386e-4 2.4639533605037855e-4 2250/5335/2253/2260/2249/2248/2247/2246/2251/8822/2254/26281/2255/27006 14 Human_papillomavirus_type_16 R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 22/4644 29/10654 4.1906254416251425e-4 7.766773440687022e-4 2.750434830629309e-4 2308/4089/4088/3630/56729/847/5443/3066/5105/4303/23410/4287/2908/4852/6648/4087/25942/2309/6720/3065/91584/10891 22 Human_papillomavirus_type_16 R-HSA-5218921 VEGFR2 mediated cell proliferation 17/4644 21/10654 5.299508347301146e-4 9.79606088440515e-4 3.469063088448986e-4 4893/5335/5579/5578/3845/3265/5921/6714/5580/3791/801/805/5170/5590/7422/10768/808 17 Human_papillomavirus_type_16 R-HSA-8849932 Synaptic adhesion-like molecules 17/4644 21/10654 5.299508347301146e-4 9.79606088440515e-4 3.469063088448986e-4 1741/1739/57622/10211/2892/2902/57497/5789/2904/2890/2319/5802/78999/2893/2903/1742/5792 17 Human_papillomavirus_type_16 R-HSA-1368082 RORA activates gene expression 15/4644 18/10654 6.552592540652224e-4 0.0012096430703335617 4.283689306354362e-4 79718/5469/1387/6907/10499/23054/85441/5465/6604/1374/6720/2033/6256/10498/8648 15 Human_papillomavirus_type_16 R-HSA-418990 Adherens junctions interactions 24/4644 33/10654 6.601690806371952e-4 0.001217105414105105 4.310115582830848e-4 283/71/1006/1500/999/3728/1008/1012/64403/1016/1010/1003/1007/1002/1000/1009/60/1015/1495/1499/1004/1005/1001/1013 24 Human_papillomavirus_type_16 R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic 111/4644 202/10654 6.85655076538573e-4 0.0012624331658577662 4.4706340119658305e-4 6811/400/11014/64837/11311/8674/51807/5861/10381/1780/5048/8655/84516/832/285643/10112/636/7846/3482/9382/81027/11004/10749/81930/10652/54732/51164/60561/79861/3797/10618/9321/29127/55605/23299/10466/23647/8398/1315/22836/3796/11316/89953/56992/91949/8729/4074/10376/2803/1314/10540/3835/3833/378/9493/26286/26958/140735/1523/84364/22820/84617/11258/1783/9585/10382/93661/55860/830/3832/7277/10671/23303/1639/81876/9183/9712/1062/347733/51143/10383/24137/84790/84643/5049/7280/829/22931/1778/5321/25839/5050/9950/63908/1781/738/10121/10226/9341/9342/57511/547/10972/381/4905/9276/55083/3799/9266/375/372 111 Human_papillomavirus_type_16 R-HSA-111447 Activation of BAD and translocation to mitochondria 13/4644 15/10654 7.591417952766465e-4 0.0013940784538915378 4.936827326681967e-4 7531/10971/7533/2810/637/7534/10000/7532/208/7529/596/207/5534 13 Human_papillomavirus_type_16 R-HSA-5654228 Phospholipase C-mediated cascade; FGFR4 13/4644 15/10654 7.591417952766465e-4 0.0013940784538915378 4.936827326681967e-4 5335/9965/2264/2253/8823/2249/2247/2246/2251/8822/8817/2254/26281 13 Human_papillomavirus_type_16 R-HSA-1839130 Signaling by activated point mutants of FGFR3 11/4644 12/10654 7.732170079590518e-4 0.001405211738557707 4.976253446368591e-4 2250/2253/8823/2249/2247/2246/8822/8817/2254/26281/2261 11 Human_papillomavirus_type_16 R-HSA-2033514 FGFR3 mutant receptor activation 11/4644 12/10654 7.732170079590518e-4 0.001405211738557707 4.976253446368591e-4 2250/2253/8823/2249/2247/2246/8822/8817/2254/26281/2261 11 Human_papillomavirus_type_16 R-HSA-210990 PECAM1 interactions 11/4644 12/10654 7.732170079590518e-4 0.001405211738557707 4.976253446368591e-4 5777/5335/5175/2534/3690/6714/7525/3685/3932/5781/4067 11 Human_papillomavirus_type_16 R-HSA-2197563 NOTCH2 intracellular domain regulates transcription 11/4644 12/10654 7.732170079590518e-4 0.001405211738557707 4.976253446368591e-4 4853/9794/55534/3280/84441/3002/10046/2208/2033/1385/3516 11 Human_papillomavirus_type_16 R-HSA-264870 Caspase-mediated cleavage of cytoskeletal proteins 11/4644 12/10654 7.732170079590518e-4 0.001405211738557707 4.976253446368591e-4 836/6709/840/2934/841/5339/28988/839/118/4137/7431 11 Human_papillomavirus_type_16 R-HSA-3371511 HSF1 activation 11/4644 12/10654 7.732170079590518e-4 0.001405211738557707 4.976253446368591e-4 7531/1915/6117/6118/10013/3297/6119/3326/10728/7415/3320 11 Human_papillomavirus_type_16 R-HSA-4641265 Repression of WNT target genes 11/4644 12/10654 7.732170079590518e-4 0.001405211738557707 4.976253446368591e-4 6932/51176/7091/83439/7089/7090/6934/7088/1487/3065/1488 11 Human_papillomavirus_type_16 R-HSA-8984722 Interleukin-35 Signalling 11/4644 12/10654 7.732170079590518e-4 0.001405211738557707 4.976253446368591e-4 3717/3572/3592/7297/6775/3595/821/6774/6772/3716/9466 11 Human_papillomavirus_type_16 R-HSA-432720 Lysosome Vesicle Biogenesis 25/4644 35/10654 7.917370634644466e-4 0.0014370078913850176 5.088852644586625e-4 8906/162/27243/1212/1174/1785/408/6456/3312/10053/9146/4074/6844/1213/1211/8907/351/9829/8905/8673/164/2647/81567/6845/375 25 Human_papillomavirus_type_16 R-HSA-69473 G2/M DNA damage checkpoint 57/4644 95/10654 8.989987298041398e-4 0.0016295803849033696 5.770806479906895e-4 83990/9156/1763/7531/7486/10971/5982/7533/2810/11200/472/4683/165918/84126/8924/672/6117/7334/7465/83695/6118/51588/51720/7534/116028/983/9656/5985/7157/5984/7158/5884/5810/80010/7532/580/11073/891/641/6119/3364/10524/144715/1111/5983/7529/5883/10111/545/7336/29086/7341/995/5932/9025/79184/7156 57 Human_papillomavirus_type_16 R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 22/4644 30/10654 9.248947226184615e-4 0.0016743578010757437 5.929376014613431e-4 11065/7321/8239/3093/7347/7328/7332/7314/90268/29089/7324/6233/7874/7317/7327/7311/997/7319/7320/7316/7322/27338 22 Human_papillomavirus_type_16 R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 26/4644 37/10654 9.278710667818569e-4 0.0016775813230604964 5.940791420524097e-4 79718/27327/9612/55818/6907/192669/4343/1071/10062/348/6257/26523/19/9682/27161/8841/347/57690/192670/9611/2874/2033/23028/6256/23112/8648 26 Human_papillomavirus_type_16 R-HSA-6784531 tRNA processing in the nucleus 37/4644 57/10654 9.308104380291905e-4 0.0016807297870720132 5.951941024856437e-4 23165/348995/57122/23511/11260/23279/23225/79074/9972/8021/55746/60528/10762/1478/79902/9883/1653/6396/129401/4928/5903/55706/7175/4927/10898/5901/8086/81929/9631/29894/79023/23636/53371/10978/9688/51493/8480 37 Human_papillomavirus_type_16 R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic 59/4644 99/10654 9.342715176346233e-4 0.0016848109758886589 5.96639367235208e-4 11014/64837/51807/5861/10381/285643/10112/7846/81027/11004/10749/81930/54732/60561/79861/3797/29127/55605/1315/3796/11316/89953/56992/8729/10376/1314/3835/3833/378/9493/26286/26958/84364/22820/84617/9585/10382/3832/7277/23303/81876/9183/1062/347733/10383/24137/84790/84643/7280/63908/547/10972/381/4905/9276/55083/3799/375/372 59 Human_papillomavirus_type_16 R-HSA-190241 FGFR2 ligand binding and activation 16/4644 20/10654 9.963775583161957e-4 0.0017945028425129942 6.354843693334834e-4 2250/2252/2253/8823/2249/2248/2247/2246/2251/2263/8822/8817/2254/26281/2255/27006 16 Human_papillomavirus_type_16 R-HSA-1296041 Activation of G protein gated Potassium channels 19/4644 25/10654 0.0010161137018229423 0.0018230275238588084 6.455857682870222e-4 2788/2550/9568/2782/2787/2792/2785/2783/2784/3759/3763/2786/54331/3761/94235/55970/2793/3768/2790 19 Human_papillomavirus_type_16 R-HSA-1296059 G protein gated Potassium channels 19/4644 25/10654 0.0010161137018229423 0.0018230275238588084 6.455857682870222e-4 2788/2550/9568/2782/2787/2792/2785/2783/2784/3759/3763/2786/54331/3761/94235/55970/2793/3768/2790 19 Human_papillomavirus_type_16 R-HSA-997272 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits 19/4644 25/10654 0.0010161137018229423 0.0018230275238588084 6.455857682870222e-4 2788/2550/9568/2782/2787/2792/2785/2783/2784/3759/3763/2786/54331/3761/94235/55970/2793/3768/2790 19 Human_papillomavirus_type_16 R-HSA-212165 Epigenetic regulation of gene expression 84/4644 149/10654 0.0010644137350699935 0.0019072445342314189 6.754094010257941e-4 51742/79595/2074/29128/9112/11335/8932/5435/5928/7913/1789/2965/23512/64425/1107/2967/23411/23378/10284/2648/2146/1788/30834/404672/9031/23309/4641/64426/79685/8850/2932/57459/2068/3066/54790/8726/9533/8467/5252/5434/9015/10514/79101/9219/1786/29115/5931/221830/8819/7270/4331/9013/1108/2966/29947/11176/54815/3720/2071/10849/57504/6908/60/25942/53615/121536/23451/5440/902/6839/9014/25885/5441/51082/6996/7343/5437/2033/3065/2968/84172/1022/10919/9188 84 Human_papillomavirus_type_16 R-HSA-1500931 Cell-Cell communication 74/4644 129/10654 0.001069944544149193 0.0019147094329608643 6.78052933456524e-4 5295/5777/6711/1365/283/71/5291/3688/29780/3852/2534/87/3861/8976/2885/6709/8826/8440/5829/3655/3918/9076/5290/1006/50848/1500/5339/6714/999/3728/1008/1012/64403/5781/3691/7016/8573/1016/1308/5747/2316/1010/1366/2318/1003/1007/140885/81/1002/1000/1364/23607/1009/2185/60/1015/1495/1499/5584/4690/3987/50855/1004/3611/667/1005/7408/3914/88/56288/1001/5296/55742/1013 74 Human_papillomavirus_type_16 R-HSA-202733 Cell surface interactions at the vascular wall 78/4644 137/10654 0.0010748335627543731 0.0019210082656616375 6.802835288234183e-4 5295/3675/5777/4893/857/5335/960/5291/7056/5175/9463/3688/2534/3690/2885/4072/6382/7040/3845/4282/3265/11136/3655/5290/6401/4312/50848/6714/965/8797/2335/23539/83692/2734/5478/7525/3685/3932/9672/5781/6464/3684/2888/10461/1277/338/8140/4267/6403/4067/140885/5624/2886/6402/6654/23657/285/3897/8795/3676/9123/2817/8793/1525/6383/5196/83953/682/23759/6520/5296/3687/1278/481/3689/2207/284/9046 78 Human_papillomavirus_type_16 R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 14/4644 17/10654 0.001266986093583095 0.0022558140727120335 7.988477640545297e-4 4790/4792/1660/3551/11035/8737/8517/5970/4791/7098/1147/4615/4793/148022 14 Human_papillomavirus_type_16 R-HSA-196299 Beta-catenin phosphorylation cascade 14/4644 17/10654 0.001266986093583095 0.0022558140727120335 7.988477640545297e-4 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/5527 14 Human_papillomavirus_type_16 R-HSA-9022699 MECP2 regulates neuronal receptors and channels 14/4644 17/10654 0.001266986093583095 0.0022558140727120335 7.988477640545297e-4 5770/4988/4204/3066/2891/2904/4233/25942/4986/114787/2289/2903/3065/1385 14 Human_papillomavirus_type_16 R-HSA-9613829 Chaperone Mediated Autophagy 17/4644 22/10654 0.0013825997656411251 0.0024585392537319374 8.706385022781818e-4 2670/1915/5116/3043/3920/3312/11315/7314/10013/6233/3326/7311/1080/7316/10226/3320/7431 17 Human_papillomavirus_type_16 R-HSA-190322 FGFR4 ligand binding and activation 12/4644 14/10654 0.001523979000115926 0.002699674920659904 9.560314833263121e-4 9965/2264/2253/8823/2249/2247/2246/2251/8822/8817/2254/26281 12 Human_papillomavirus_type_16 R-HSA-198323 AKT phosphorylates targets in the cytosol 12/4644 14/10654 0.001523979000115926 0.002699674920659904 9.560314833263121e-4 7249/2932/10000/2931/23608/208/1147/842/207/1027/1026/4193 12 Human_papillomavirus_type_16 R-HSA-399955 SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion 12/4644 14/10654 0.001523979000115926 0.002699674920659904 9.560314833263121e-4 5361/8829/2534/5362/5879/27289/23396/7094/10371/55558/91584/2242 12 Human_papillomavirus_type_16 R-HSA-9024446 NR1H2 and NR1H3-mediated signaling 31/4644 47/10654 0.0016201488235200445 0.002859866821332136 0.0010127599802444147 79718/27327/9612/55818/6907/192669/4343/1071/10062/348/6257/26523/5105/6319/19/9682/27161/8841/347/8204/57690/6720/192670/9611/2874/2194/2033/23028/6256/23112/8648 31 Human_papillomavirus_type_16 R-HSA-111458 Formation of apoptosome 10/4644 11/10654 0.0016368304045115503 0.002859866821332136 0.0010127599802444147 55075/5594/22900/331/57099/317/56616/5595/842/54205 10 Human_papillomavirus_type_16 R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 10/4644 11/10654 0.0016368304045115503 0.002859866821332136 0.0010127599802444147 64344/3091/1387/2056/405/768/10370/2034/7422/2033 10 Human_papillomavirus_type_16 R-HSA-1839122 Signaling by activated point mutants of FGFR1 10/4644 11/10654 0.0016368304045115503 0.002859866821332136 0.0010127599802444147 2250/2253/2260/2249/2247/2246/2251/8822/2254/26281 10 Human_papillomavirus_type_16 R-HSA-2025928 Calcineurin activates NFAT 10/4644 11/10654 0.0016368304045115503 0.002859866821332136 0.0010127599802444147 5530/4773/5478/801/805/4772/4775/5532/5534/808 10 Human_papillomavirus_type_16 R-HSA-2468052 Establishment of Sister Chromatid Cohesion 10/4644 11/10654 0.0016368304045115503 0.002859866821332136 0.0010127599802444147 10274/157570/113130/23047/5885/8243/23244/10735/9126/114799 10 Human_papillomavirus_type_16 R-HSA-4755510 SUMOylation of immune response proteins 10/4644 11/10654 0.0016368304045115503 0.002859866821332136 0.0010127599802444147 4792/6612/51588/8517/5970/4791/10210/7329/9641/7341 10 Human_papillomavirus_type_16 R-HSA-77588 SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs 10/4644 11/10654 0.0016368304045115503 0.002859866821332136 0.0010127599802444147 134353/6636/6635/7884/84967/6637/22916/4686/6634/6628 10 Human_papillomavirus_type_16 R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 10/4644 11/10654 0.0016368304045115503 0.002859866821332136 0.0010127599802444147 627/4893/2885/3845/3265/4909/5781/6654/4915/10818 10 Human_papillomavirus_type_16 R-HSA-9627069 Regulation of the apoptosome activity 10/4644 11/10654 0.0016368304045115503 0.002859866821332136 0.0010127599802444147 55075/5594/22900/331/57099/317/56616/5595/842/54205 10 Human_papillomavirus_type_16 R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 10/4644 11/10654 0.0016368304045115503 0.002859866821332136 0.0010127599802444147 7314/257397/23118/80216/10454/6233/7189/7311/6885/7316 10 Human_papillomavirus_type_16 R-HSA-452723 Transcriptional regulation of pluripotent stem cells 18/4644 24/10654 0.0017991649348259677 0.003135687457839544 0.0011104358930864424 64344/79727/6657/4089/2516/5460/2041/5087/2247/63978/6774/9314/79923/4087/2034/7547/27086/57167 18 Human_papillomavirus_type_16 R-HSA-982772 Growth hormone receptor signaling 18/4644 24/10654 0.0017991649348259677 0.003135687457839544 0.0011104358930864424 5777/5770/9021/6776/3717/6868/8660/1154/3667/5594/5617/6777/6774/6772/8651/4067/5595/25970 18 Human_papillomavirus_type_16 R-HSA-193704 p75 NTR receptor-mediated signalling 57/4644 97/10654 0.0018020635623690892 0.0031368426526102136 0.001110844980329385 7984/4790/7531/29/8878/1894/23385/10276/4792/9138/836/23365/3654/6868/8997/8874/3551/7314/5879/9181/8767/6453/9828/5970/396/3066/6233/7410/7409/6610/26574/5663/84894/7204/27237/7074/10451/11108/7189/6654/7311/387/6655/4804/57142/8841/5584/10018/835/23421/4615/7316/4168/4803/3065/5599/10672 57 Human_papillomavirus_type_16 R-HSA-3928664 Ephrin signaling 15/4644 19/10654 0.0018535789890553392 0.0032225171271928637 0.0011411847424954284 2051/2047/2534/8440/8874/5062/5879/6714/1949/10627/5063/6386/2048/5058/28964 15 Human_papillomavirus_type_16 R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF) 35/4644 55/10654 0.0021234780481514484 0.0036871778484609927 0.0013057342870342414 79718/10484/3638/5469/1387/6907/4801/9632/10499/23054/85441/31/8720/5465/2222/6667/6604/6319/6721/4800/57678/32/5901/9871/3837/4802/6720/2194/4597/6256/10498/2224/4520/8648/10427 35 Human_papillomavirus_type_16 R-HSA-983189 Kinesins 37/4644 59/10654 0.002345259187245136 0.004067241829054297 0.0014403257255607368 64837/51807/10381/285643/10112/7846/81027/11004/10749/81930/79861/3797/29127/55605/3796/89953/56992/10376/3835/3833/9493/84617/9585/10382/3832/7277/23303/1062/347733/10383/24137/84790/84643/7280/547/55083/3799 37 Human_papillomavirus_type_16 R-HSA-9018519 Estrogen-dependent gene expression 83/4644 150/10654 0.0023638181142902506 0.004094366437468175 0.0014499313189668594 3725/7764/7031/7039/27327/10274/5431/5435/5433/1509/5469/1105/4609/1387/8312/5439/192669/10499/1386/4343/904/6387/51523/5438/865/1655/6667/2099/8850/595/1025/2353/26523/2957/2963/3838/5434/7090/5241/5436/5885/57678/7033/2962/10524/8243/4602/3326/23030/6908/3169/5432/10728/7528/3727/27161/2354/596/5440/9687/8204/5430/5451/2625/57690/5441/10735/192670/7391/5437/3320/2033/9126/3065/2066/861/23028/23112/10498/3276/8202/8648/2288 83 Human_papillomavirus_type_16 R-HSA-190242 FGFR1 ligand binding and activation 13/4644 16/10654 0.002424113095594123 0.004188461420096742 0.0014832530219346981 2250/2253/2260/2249/2248/2247/2246/2251/8822/2254/26281/2255/27006 13 Human_papillomavirus_type_16 R-HSA-399956 CRMPs in Sema3A signaling 13/4644 16/10654 0.002424113095594123 0.004188461420096742 0.0014832530219346981 5361/8829/2534/1808/5362/10371/2932/55558/1020/1809/91584/8851/2242 13 Human_papillomavirus_type_16 R-HSA-5620916 VxPx cargo-targeting to cilium 16/4644 21/10654 0.0024889430737916477 0.004295187124882758 0.0015210476219714609 55763/60412/6010/5310/8729/11336/117177/378/4218/50807/55770/23265/10640/8766/149371/54536 16 Human_papillomavirus_type_16 R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 75/4644 134/10654 0.002495844386836325 0.004301805497212978 0.0015233913753869722 5579/7042/5175/3959/5578/5582/3082/7423/3920/3309/3690/87/10487/7040/54863/350/7043/5054/5099/1072/7018/5340/813/7094/7414/10490/6810/7123/7273/22927/1191/9749/27154/226/2335/5478/5154/7076/801/805/351/135228/7424/2316/3674/7277/334/335/308/6403/197/81/9948/3481/5473/8407/29789/10916/7422/5196/3827/1950/5216/6647/7078/55664/5345/2/88/3479/5155/808/213/5660/7057 75 Human_papillomavirus_type_18 R-HSA-3700989 Transcriptional Regulation by TP53 281/1364 365/10654 2.9250605948705603e-183 3.632925258829236e-180 1.6072438216025606e-180 23368/6884/1017/23774/6875/834/6118/2176/80010/27161/27113/5563/3725/9891/9134/5434/5440/27165/4436/83990/8621/902/83667/1820/64769/7862/9156/3622/57060/5883/1763/7531/1029/7027/1459/25946/79370/7486/9540/5430/10111/5457/8793/9219/6874/8445/7532/207/10971/5436/55240/9997/22974/133383/9212/57690/204851/7832/4849/6878/1027/58484/4869/3486/5982/51422/7249/27327/898/5931/355/7295/4850/7533/2810/55367/1460/6749/4292/11200/545/472/117584/53632/27244/5441/79813/8794/192670/7534/332/5438/580/8550/5431/11073/9337/5934/639/5435/64065/7316/5433/1869/891/6872/28996/116028/890/80196/2539/84289/1457/54971/4331/10769/983/1026/54205/5366/6790/641/5933/124446/5111/25904/1108/1643/8148/8797/246175/5395/29117/4194/6879/84883/9656/5519/112858/6119/1647/147923/5928/3364/5876/1432/143686/5571/10524/10848/1387/54457/4683/4848/27154/56950/5437/8812/144715/5458/83860/57459/23019/1616/51499/843/28984/10000/6794/2965/5985/54815/51755/2877/2033/995/94241/1874/10128/84126/5728/900/7994/2068/54541/5439/1111/192669/3066/3065/2071/7157/1107/8900/5984/91875/8626/6873/5371/23112/208/10498/10542/6233/5527/2968/2475/672/55571/5932/1025/2353/604/7311/63970/7161/839/6881/5562/51616/5518/1386/55835/6880/6908/10419/5325/8851/5300/7156/581/5983/4343/6117/11198/50484/5600/7159/57472/6883/3276/144455/85456/79733/29883/26523/51497/5564/7874/51230/6882/5052/637/317/5565/1020/138474/133746/5884/5810/53615/10397/1022/8795/5432/665/26155/26013/8178/5875/83695/10919/6877/7529/7296/7314/4193/5515/1263/27166/5516 281 Human_papillomavirus_type_18 R-HSA-5633007 Regulation of TP53 Activity 146/1364 160/10654 3.3228615122450564e-115 2.06349699910418e-112 9.12912478627326e-113 23368/6884/1017/23774/6875/6118/80010/5563/9891/83990/64769/7862/9156/3622/5883/1763/1029/1459/25946/7486/10111/5457/9219/6874/8445/207/22974/133383/9212/204851/6878/5982/51422/5931/1460/6749/11200/545/472/117584/53632/79813/580/8550/11073/639/7316/6872/28996/116028/890/80196/84289/1457/54971/983/6790/641/1108/8148/29117/4194/6879/5519/112858/6119/5928/3364/1432/5571/10524/10848/54457/4683/27154/56950/144715/5458/83860/57459/1616/10000/6794/5985/54815/2033/94241/84126/900/7994/1111/3066/3065/7157/1107/8900/5984/91875/8626/6873/5371/208/6233/5527/2475/672/5932/7311/7161/6881/5562/51616/5518/6880/6908/10419/8851/5300/7156/5983/6117/11198/5600/7159/6883/5564/7874/51230/6882/5565/1020/138474/133746/5884/5810/53615/26155/26013/83695/10919/6877/7314/4193/5515/1263/5516 146 Human_papillomavirus_type_18 R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 91/1364 92/10654 3.2125166313168366e-81 1.3299818853651704e-78 5.883977829990838e-79 6884/1017/6875/6118/80010/5563/9891/83990/9156/5883/1763/1459/7486/10111/6874/8445/22974/9212/204851/6878/5982/51422/1460/6749/11200/545/472/53632/580/8550/11073/7316/6872/28996/116028/890/1457/6790/641/8148/4194/6879/112858/6119/3364/1432/5571/10524/54457/4683/144715/83860/6794/5985/94241/84126/1111/7157/8900/5984/6873/6233/672/5932/7311/6881/5562/51616/6880/6908/8851/5300/7156/5983/6117/11198/5600/6883/5564/6882/5565/1020/138474/5884/5810/26155/83695/6877/7314/4193/1263 91 Human_papillomavirus_type_18 R-HSA-6807070 PTEN Regulation 116/1364 140/10654 1.086799355789279e-80 3.3745119997257117e-78 1.4929191150579045e-78 1912/5718/5689/27161/3725/6591/5684/8841/5720/5682/5468/1822/23186/1459/5700/122706/5707/2146/5978/9112/9219/8535/10273/207/51564/6045/5690/57690/5594/84232/5717/9491/23198/27327/80012/5931/1460/143471/5706/5705/10197/192670/7316/10213/5709/5695/1457/1911/5714/1108/57167/2122/9861/7101/10014/5715/5711/1958/5928/5701/5688/84733/5687/57459/5685/5683/5698/5708/10000/5692/54815/5686/5713/23512/57332/5728/5699/5710/6615/5702/192669/3066/3065/7157/1107/23028/5719/5987/5371/23112/208/10542/5704/6233/2475/5716/57504/7311/1386/331/4343/8726/648/5694/23466/26523/7874/53615/5693/5721/5696/23608/5691/7314/6015/5595 116 Human_papillomavirus_type_18 R-HSA-5663205 Infectious disease 198/1364 383/10654 6.121110148011053e-79 1.5204837607659457e-76 6.726777888972146e-77 6158/6884/5718/3303/6875/5689/6138/8945/6144/3837/3838/6203/5434/5440/5684/5903/9349/4736/7852/5720/902/6194/6191/7175/6128/5606/5682/51121/6132/9631/1499/1938/3159/6147/6129/6217/5700/122706/5707/5430/6874/6230/6222/5436/6152/5690/6136/7520/6878/6125/5717/4869/9491/23198/6500/6749/6224/6154/51065/6141/143471/6202/5706/5705/5441/23636/10197/6232/5438/6134/5431/6160/6164/5435/7316/6155/10213/5709/6175/9978/5433/6218/5695/6872/292/4233/4331/4836/9397/6209/5714/6193/6714/4927/6210/6231/6229/9688/8148/6205/6165/9861/6130/6879/5715/6142/3840/5711/6204/5701/5688/54457/6228/5437/8812/23521/5687/83860/23225/999/5685/5683/5698/5708/3320/5692/2965/5686/128866/5713/140801/6156/5699/6143/5710/2068/6181/5439/6124/5702/2071/5901/6207/6873/5719/5609/5704/6233/3326/2968/5716/7514/1025/7311/6223/9972/6881/51616/1213/5610/6880/6908/1211/6188/6189/8021/7251/11198/6396/6135/6201/6161/6883/5694/3304/1104/51497/2547/9045/6882/6187/138474/1022/5432/6168/5693/6208/10254/5721/6137/5696/8178/5691/8480/6122/6877/7296/7314 198 Human_papillomavirus_type_18 R-HSA-2262752 Cellular responses to stress 209/1364 479/10654 1.6888680243873933e-66 3.495956810481904e-64 1.5466475591758237e-64 1912/5718/1017/3303/6118/5689/3725/9134/1019/5684/5903/5601/5720/573/83667/4790/7175/5241/5606/5682/9631/3159/112399/7531/7290/1029/7027/1915/5700/122706/7321/5707/2146/10111/8535/51807/6045/7422/5690/57690/5594/3308/5717/1027/9491/23198/27327/80012/898/10049/5931/7295/10294/5925/3091/7277/1051/1410/10013/143471/545/5706/472/27244/5705/23636/79813/10197/3337/192670/3576/3313/8550/29855/7316/10213/5709/9978/2114/1869/5695/890/3305/6774/5970/1026/1911/9532/54205/832/6667/5714/4927/9688/7415/9861/4194/1031/5715/6119/5711/5598/3552/5928/10370/1432/2932/5701/10524/5688/1387/84733/4683/5687/57805/7846/23225/3310/2908/5685/5683/3309/5698/5708/3320/5602/5692/5686/5713/2877/2033/23512/1021/7266/57332/6195/5699/5710/25842/3301/816/7428/5702/192669/10540/7157/8900/6648/23135/5719/8091/23112/5609/8131/10542/5704/6233/3326/2475/5716/3306/2353/1030/51343/6196/7311/367/9972/57634/10383/23411/84790/8021/9529/4343/8726/55662/6117/6197/5599/6396/648/5600/5694/3304/3312/23466/26523/5052/2113/405/3569/5693/5721/5696/7280/2288/5691/8480/10919/768/10728/7296/7314/23523/6015/5595/4193/2950 209 Human_papillomavirus_type_18 R-HSA-1257604 PIP3 activates AKT signaling 148/1364 264/10654 7.344417404861529e-65 1.303109488119717e-62 5.765091556898826e-63 1912/1147/5718/5689/27161/3725/6591/5684/8841/5290/5720/2309/5682/5468/1822/23186/1459/842/5700/3815/122706/5707/2146/5978/9112/9219/8535/10273/207/51564/6045/5690/57690/5594/4303/84232/5717/1027/9491/7249/23198/27327/80012/5931/1460/143471/5706/2064/5705/10197/192670/2100/7316/10213/5709/1950/5695/1457/4233/1026/1911/5714/6714/2099/1108/57167/2122/9861/7101/10014/5715/5519/5711/1958/5928/2932/5701/5688/84733/5159/5687/57459/2247/5685/3164/5683/5698/5708/10000/5692/54815/5686/5713/23512/57332/5728/5699/5710/6615/2264/3630/5702/192669/3066/3065/7157/1107/2066/23028/5719/5987/7189/5371/23112/208/10542/5704/6233/5527/2475/5716/1385/57504/7311/5518/1386/1956/331/4343/8726/648/5694/23466/26523/7874/53615/5693/5721/5696/23608/5691/5156/7314/6015/5595/4193/5515/5516 148 Human_papillomavirus_type_18 R-HSA-8953897 Cellular responses to external stimuli 209/1364 493/10654 8.184697285146055e-64 1.270674253518925e-61 5.621594714271369e-62 1912/5718/1017/3303/6118/5689/3725/9134/1019/5684/5903/5601/5720/573/83667/4790/7175/5241/5606/5682/9631/3159/112399/7531/7290/1029/7027/1915/5700/122706/7321/5707/2146/10111/8535/51807/6045/7422/5690/57690/5594/3308/5717/1027/9491/23198/27327/80012/898/10049/5931/7295/10294/5925/3091/7277/1051/1410/10013/143471/545/5706/472/27244/5705/23636/79813/10197/3337/192670/3576/3313/8550/29855/7316/10213/5709/9978/2114/1869/5695/890/3305/6774/5970/1026/1911/9532/54205/832/6667/5714/4927/9688/7415/9861/4194/1031/5715/6119/5711/5598/3552/5928/10370/1432/2932/5701/10524/5688/1387/84733/4683/5687/57805/7846/23225/3310/2908/5685/5683/3309/5698/5708/3320/5602/5692/5686/5713/2877/2033/23512/1021/7266/57332/6195/5699/5710/25842/3301/816/7428/5702/192669/10540/7157/8900/6648/23135/5719/8091/23112/5609/8131/10542/5704/6233/3326/2475/5716/3306/2353/1030/51343/6196/7311/367/9972/57634/10383/23411/84790/8021/9529/4343/8726/55662/6117/6197/5599/6396/648/5600/5694/3304/3312/23466/26523/5052/2113/405/3569/5693/5721/5696/7280/2288/5691/8480/10919/768/10728/7296/7314/23523/6015/5595/4193/2950 209 Human_papillomavirus_type_18 R-HSA-9010553 Regulation of expression of SLITs and ROBOs 111/1364 171/10654 6.530788721782543e-58 9.012488436059908e-56 3.987218377509342e-56 6158/5718/5689/6138/6144/6203/5684/9349/4736/5720/6194/6191/6128/5682/51121/6132/6147/6129/6217/5700/122706/5707/6230/6222/6152/5690/6136/6125/5717/9491/23198/6224/6154/51065/6141/26986/143471/6202/5706/5705/10197/6232/6134/6160/6164/7316/6155/10213/5709/6175/9978/6218/5695/6209/5714/6193/6210/6231/6229/6205/6165/9861/6130/5715/6142/5711/6204/5701/5688/6228/23521/5687/5685/5683/5698/5708/5692/5686/5713/140801/6156/5699/6143/5710/6181/6124/5702/6207/5719/5704/6233/5716/7311/6223/6188/6189/6135/6201/6161/5694/9045/6187/6168/5693/6208/5721/6137/5696/5691/6122/7314 111 Human_papillomavirus_type_18 R-HSA-9006925 Intracellular signaling by second messengers 151/1364 305/10654 1.5057385162940513e-56 1.8701272372372117e-54 8.27363690005784e-55 1912/1147/5718/5689/27161/3725/6591/3838/5684/8841/5290/5720/2309/5682/5468/1822/23186/1459/842/5700/3815/122706/5707/2146/5978/9112/9219/8535/10273/207/51564/6045/5690/57690/5594/4303/84232/5717/1027/9491/7249/23198/27327/80012/5931/1460/143471/5706/2064/5705/10197/192670/2100/7316/10213/5709/1950/5695/1457/4233/1026/1911/5714/6714/2099/1108/57167/2122/9861/7101/10014/5715/5519/5711/1958/5928/2932/5701/5688/84733/5159/5687/57459/2247/5685/3164/5683/5698/5708/10000/5692/54815/5686/5713/23512/57332/5728/5699/5710/6615/2264/816/3630/5702/192669/3066/3065/7157/1107/2066/23028/5719/5987/7189/5371/23112/208/10542/5704/6233/5527/5580/2475/5716/1385/57504/7311/5518/1386/1956/331/4343/8726/648/5694/23466/26523/7874/53615/5693/5721/5696/23608/5691/5156/7314/6015/5595/4193/5515/5516 151 Human_papillomavirus_type_18 R-HSA-69563 p53-Dependent G1 DNA Damage Response 64/1364 66/10654 3.2892153189246214e-55 3.4043378550869834e-53 1.5061143828760108e-53 5718/1017/5689/9134/5684/5720/5682/57060/1029/25946/5700/122706/5707/5690/5717/1027/9491/23198/898/11200/143471/5706/472/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/8900/5719/5704/6233/5716/7311/5694/51230/5693/5721/5696/5691/7314/4193 64 Human_papillomavirus_type_18 R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 64/1364 66/10654 3.2892153189246214e-55 3.4043378550869834e-53 1.5061143828760108e-53 5718/1017/5689/9134/5684/5720/5682/57060/1029/25946/5700/122706/5707/5690/5717/1027/9491/23198/898/11200/143471/5706/472/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/8900/5719/5704/6233/5716/7311/5694/51230/5693/5721/5696/5691/7314/4193 64 Human_papillomavirus_type_18 R-HSA-69615 G1/S DNA Damage Checkpoints 65/1364 68/10654 8.294947870729901e-55 7.92486558111272e-53 3.5060427437417072e-53 5718/1017/5689/9134/5684/5720/5682/57060/1029/25946/5700/122706/5707/5690/5717/1027/9491/23198/898/11200/143471/5706/472/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/7157/8900/5719/5704/6233/5716/7311/5694/51230/5693/5721/5696/5691/7314/4193 65 Human_papillomavirus_type_18 R-HSA-8878166 Transcriptional regulation by RUNX2 89/1364 121/10654 8.652521794769117e-54 7.676022906502316e-52 3.3959521630597584e-52 57154/5718/8493/5689/7291/25/1019/5684/8841/5720/5682/5700/122706/5707/23462/10273/207/5690/5594/5717/9491/23198/6500/4086/5925/10013/143471/5706/5705/10197/7316/10213/5709/9978/891/5695/4094/9759/983/1026/5714/6772/6714/2099/9861/4089/5715/5711/2932/5701/5688/5687/6502/2908/5685/5683/5698/5708/10000/5692/5686/5713/595/55294/5699/5710/5702/5719/208/5704/6233/5716/23493/7311/25937/367/860/10432/581/5694/5693/5721/5696/4091/5691/117581/10891/7314/5595 89 Human_papillomavirus_type_18 R-HSA-69481 G2/M Checkpoints 106/1364 168/10654 1.7096547748536129e-53 1.4155941535787915e-51 6.262735385779551e-52 5718/1017/6118/5689/80010/5684/5720/83990/5682/9156/5883/1763/7531/51512/5700/7486/122706/5707/10111/7532/10971/5690/51588/51720/5717/5982/9491/23198/63967/7533/2810/11200/143471/545/5706/472/5705/10197/7336/7534/580/11073/7316/10213/5709/891/5695/116028/983/84515/641/5714/9861/5715/9656/6119/5711/3364/7341/5701/10524/5688/4683/5687/144715/5685/5683/5698/5708/5692/5985/5686/5713/995/84126/5699/5710/1111/5702/7157/5984/5719/8924/5704/6233/5716/672/5932/7158/7311/79184/7156/5983/6117/7334/5694/7465/5884/5810/5693/5721/5696/83695/5691/7529/7314 106 Human_papillomavirus_type_18 R-HSA-5663202 Diseases of signal transduction 166/1364 377/10654 4.0250257391442477e-53 3.1244262300107225e-51 1.382278576206117e-51 4000/1147/5718/27123/5689/8805/5434/5440/5684/4893/8841/5290/5720/79718/79885/1487/2309/5682/1499/2648/10018/9734/55869/842/5700/3815/122706/5707/5430/23462/207/51564/5436/1452/5690/55534/5594/4303/613/5717/1027/9491/7249/23198/6500/5908/84441/10533/10013/143471/5706/2064/5705/5441/10197/10046/5438/5431/6776/2100/5435/84447/7316/10213/5709/83933/9978/5433/1950/9611/5695/6774/4233/9759/9612/1026/1024/5714/6772/6714/2099/4609/7415/9861/4089/10014/5715/22938/5519/8850/5711/2932/5701/5688/1387/5437/5159/5687/3717/4088/2247/5685/6907/3164/5683/5698/5708/10000/3320/5692/5686/5713/2033/54894/55294/5728/5699/8312/5710/5439/2264/816/5702/3066/3065/2066/4087/5719/208/9794/5704/6233/5527/2475/5716/1385/23493/7311/8826/5518/6469/1956/60/3845/6777/5694/3265/3516/369/4763/4851/5432/5693/5663/5721/5696/7750/5691/5245/7529/5156/7314/5595/4193/5515/5516 166 Human_papillomavirus_type_18 R-HSA-453279 Mitotic G1-G1/S phases 98/1364 149/10654 5.8859979212138415e-52 4.300240834204465e-50 1.902471154720511e-50 5718/1017/6118/5689/25/9134/1019/5684/5720/902/5682/1029/7027/5700/5707/207/5690/5717/1027/9491/6500/7153/898/5925/5706/5705/10197/91768/5934/7316/10213/5709/5422/1869/891/5695/890/4331/983/1026/84515/5933/5714/5111/6714/4609/9861/1031/5715/5519/6119/5711/5928/5701/5688/5687/4067/3717/6502/5685/5683/5698/5708/10000/5692/5686/5713/1021/1874/595/5699/5710/5702/3065/8900/5719/208/5704/6233/5716/1030/7311/5518/6117/1719/5694/7465/1022/5693/5721/5696/7083/5691/1028/7314/5515/6241/5516 98 Human_papillomavirus_type_18 R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 72/1364 85/10654 1.3979829015208614e-51 9.6460820204939435e-050 4.267526752011051e-50 5718/1017/5689/9134/1019/5684/5720/902/5682/7027/5700/5707/207/5690/5717/1027/9491/6500/898/5925/5706/5705/10197/91768/5934/7316/10213/5709/1869/5695/890/4331/1026/5714/4609/9861/5715/5711/5928/5701/5688/5687/6502/5685/5683/5698/5708/10000/5692/5686/5713/1874/595/5699/5710/5702/8900/5719/208/5704/6233/5716/51343/7311/5694/7465/1022/5693/5721/5696/5691/7314 72 Human_papillomavirus_type_18 R-HSA-69202 Cyclin E associated events during G1/S transition 71/1364 83/10654 1.70419293828709e-51 1.1140040154487188e-49 4.928469328453523e-50 5718/1017/5689/9134/1019/5684/5720/902/5682/7027/5700/5707/207/5690/5717/1027/9491/6500/898/5925/5706/5705/10197/91768/5934/7316/10213/5709/1869/5695/890/4331/1026/5714/4609/9861/5715/5711/5928/5701/5688/5687/6502/5685/5683/5698/5708/10000/5692/5686/5713/1874/595/5699/5710/5702/8900/5719/208/5704/6233/5716/7311/5694/7465/1022/5693/5721/5696/5691/7314 71 Human_papillomavirus_type_18 R-HSA-376176 Signaling by ROBO receptors 119/1364 218/10654 2.136315048199434e-50 1.3266516449318485e-48 5.869244500842656e-49 6158/5718/5689/6138/6144/25/55740/6203/5684/9349/4736/7852/5720/6194/6191/6128/5682/51121/6132/6147/10298/6129/6217/5700/122706/5707/6230/6222/6152/5690/6136/6125/5717/9491/23198/6224/6154/51065/6141/26986/143471/6202/5706/5705/10197/6232/6134/6160/6164/7316/6155/10213/5709/6175/9978/6218/5695/6209/5714/6193/6714/6210/6231/6229/6205/6165/9861/6130/5715/6142/5711/6204/5701/5688/6228/23521/5687/5685/5683/5698/5708/5692/5686/5713/7408/140801/6156/5699/6143/5710/6181/6124/5702/998/6207/5719/5704/6233/5716/7311/6223/6188/6189/6135/6201/6161/5694/9045/6187/6168/5693/6208/5721/6137/5696/5691/6122/7314/6387 119 Human_papillomavirus_type_18 R-HSA-8878159 Transcriptional regulation by RUNX3 76/1364 96/10654 3.703628387377814e-50 2.1904316462491645e-48 9.690696833138942e-49 57154/5718/5689/8463/5684/5720/2309/5682/1499/2648/10018/1029/864/5700/5707/5690/55534/5717/9491/84441/5706/5705/6097/10197/10046/6696/7316/10213/5709/5695/9759/1026/5714/6714/4609/9861/4089/5715/22938/8850/5711/5701/5688/1387/5687/4088/5685/5683/5698/5708/5692/5686/5713/2033/595/5699/5710/5702/7157/5719/9794/5704/6233/5716/7311/25937/3845/5694/3516/4851/5693/5721/5696/5691/7314/4193 76 Human_papillomavirus_type_18 R-HSA-168255 Influenza Life Cycle 94/1364 144/10654 2.034586157511554e-49 1.14861636710425e-47 5.081597962780054e-48 6158/3303/6138/6144/3837/6203/5434/5440/5903/9349/4736/6194/6191/7175/6128/51121/6132/9631/6147/6129/6217/5430/6230/6222/5436/6152/6136/6125/6224/6154/51065/6141/6202/5441/23636/6232/5438/6134/5431/6160/6164/5435/6155/6175/5433/6218/6209/6193/4927/6210/6231/6229/9688/6205/6165/6130/6142/6204/6228/5437/23521/23225/3320/140801/6156/6143/6181/5439/6124/5901/6207/6233/7514/7311/6223/9972/1213/1211/6188/6189/8021/6396/6135/6201/6161/3304/9045/6187/5432/6168/6208/6137/8480/6122 94 Human_papillomavirus_type_18 R-HSA-109581 Apoptosis 105/1364 178/10654 6.526285858758934e-49 3.524194363729824e-47 1.5591401456623175e-47 23368/4000/5718/5689/2934/27113/3837/596/5684/5720/1612/5682/1499/10018/7531/5747/1029/7027/842/5700/122706/5707/7532/207/10971/5690/5594/5717/9491/23198/63967/355/7533/2810/143471/5706/5705/841/10197/7534/7316/10213/5709/1869/5695/6774/54205/4836/5366/5714/8797/3146/9861/5715/5711/5701/5688/5687/999/598/836/5685/5683/5698/5708/10000/5692/5686/708/5713/8837/5534/5699/5710/5702/7157/8626/5719/208/5704/6233/5580/5716/1613/7311/7161/839/331/581/5599/7159/7431/5694/26060/637/317/8795/5693/5721/5696/5691/7529/7314/578/5595 105 Human_papillomavirus_type_18 R-HSA-168254 Influenza Infection 97/1364 155/10654 1.632329306645239e-48 8.447304161889111e-47 3.737174991529889e-47 6158/3303/6138/6144/3837/3838/6203/5434/5440/5903/9349/4736/6194/6191/7175/6128/51121/6132/9631/6147/6129/6217/5430/6230/6222/5436/6152/6136/6125/6224/6154/51065/6141/6202/5441/23636/6232/5438/6134/5431/6160/6164/5435/6155/6175/5433/6218/6209/6193/4927/6210/6231/6229/9688/6205/6165/6130/6142/3840/6204/6228/5437/23521/23225/3320/140801/6156/6143/6181/5439/6124/5901/6207/6233/7514/7311/6223/9972/1213/5610/1211/6188/6189/8021/6396/6135/6201/6161/3304/9045/6187/5432/6168/6208/6137/8480/6122 97 Human_papillomavirus_type_18 R-HSA-69620 Cell Cycle Checkpoints 138/1364 293/10654 2.481291826125241e-48 1.2327057792190197e-46 5.453618245210002e-47 5718/1017/6118/5689/80010/11130/9134/5684/5903/5720/83990/5682/9156/57060/5883/1763/7531/51512/1029/25946/1058/5700/7486/122706/7321/5707/991/10111/7532/10971/5690/9212/51588/51720/5717/1027/5982/9491/23198/63967/898/7533/2810/11200/143471/545/5706/472/5705/10197/7336/6232/7534/332/580/11073/7316/10213/5709/891/5695/5501/116028/890/983/1026/84515/641/5714/9861/4194/3796/5715/9656/5519/6119/5711/3364/7341/5701/10524/5688/4683/699/5687/144715/5685/5683/5698/5708/5692/5985/5686/5713/995/84126/5699/5710/1111/5702/7157/8900/5984/5719/8924/5704/6233/5527/5716/701/672/7514/5932/7158/7311/79184/5518/5347/7156/5983/6117/6396/7334/5694/7465/51230/5884/5810/5693/5721/5696/83695/5691/7529/7314/4193/5515/5516 138 Human_papillomavirus_type_18 R-HSA-5357801 Programmed Cell Death 105/1364 181/10654 6.171541582786682e-48 2.948097940700407e-46 1.3042691118277929e-46 23368/4000/5718/5689/2934/27113/3837/596/5684/5720/1612/5682/1499/10018/7531/5747/1029/7027/842/5700/122706/5707/7532/207/10971/5690/5594/5717/9491/23198/63967/355/7533/2810/143471/5706/5705/841/10197/7534/7316/10213/5709/1869/5695/6774/54205/4836/5366/5714/8797/3146/9861/5715/5711/5701/5688/5687/999/598/836/5685/5683/5698/5708/10000/5692/5686/708/5713/8837/5534/5699/5710/5702/7157/8626/5719/208/5704/6233/5580/5716/1613/7311/7161/839/331/581/5599/7159/7431/5694/26060/637/317/8795/5693/5721/5696/5691/7529/7314/578/5595 105 Human_papillomavirus_type_18 R-HSA-69206 G1/S Transition 88/1364 131/10654 7.129626927434737e-48 3.279628386619979e-46 1.450941620320052e-46 5718/1017/6118/5689/9134/1019/5684/5720/902/5682/7027/5700/5707/207/5690/5717/1027/9491/6500/898/5925/5706/5705/10197/91768/5934/7316/10213/5709/5422/1869/891/5695/890/4331/983/1026/84515/5933/5714/5111/4609/9861/5715/5519/6119/5711/5928/5701/5688/5687/6502/5685/5683/5698/5708/10000/5692/5686/5713/1874/595/5699/5710/5702/3065/8900/5719/208/5704/6233/5716/7311/5518/6117/1719/5694/7465/1022/5693/5721/5696/7083/5691/7314/5515/6241/5516 88 Human_papillomavirus_type_18 R-HSA-69541 Stabilization of p53 55/1364 57/10654 3.7471158603044013e-47 1.6621135351778807e-45 7.353362703304127e-46 5718/5689/5684/5720/5682/1029/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/472/5705/10197/7316/10213/5709/5695/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/51230/5693/5721/5696/5691/7314/4193 55 Human_papillomavirus_type_18 R-HSA-162906 HIV Infection 119/1364 233/10654 2.426195324023451e-46 1.0390808939438366e-44 4.5970016665707494e-45 6884/5718/6875/5689/8945/3837/5434/5440/5684/5903/7852/5720/902/7175/5682/9631/3159/5700/122706/5707/5430/6874/5436/5690/7520/6878/5717/4869/9491/23198/6500/6749/143471/5706/5705/5441/23636/10197/5438/5431/5435/7316/10213/5709/9978/5433/5695/6872/292/4331/4836/9397/5714/4927/9688/8148/9861/6879/5715/5711/5701/5688/54457/5437/8812/5687/83860/23225/5685/5683/5698/5708/5692/2965/5686/128866/5713/5699/5710/2068/5439/5702/2071/5901/6873/5719/5704/6233/2968/5716/7514/1025/7311/9972/6881/51616/6880/6908/8021/7251/11198/6396/6883/5694/1104/51497/2547/6882/138474/1022/5432/5693/5721/5696/8178/5691/8480/6877/7314 119 Human_papillomavirus_type_18 R-HSA-9013694 Signaling by NOTCH4 67/1364 82/10654 5.2967832260066686e-46 2.1928682555667606e-44 9.701476645528003e-45 5718/5689/5684/5720/5682/2648/5700/5707/23462/207/5690/55534/5717/9491/6500/84441/5706/5705/10197/10046/7534/7316/10213/5709/9978/5695/5714/9861/5715/22938/8850/5711/5701/5688/1387/5687/4088/5685/5683/5698/5708/59/5692/5686/5713/2033/4855/55294/5699/5710/5702/5719/9794/5704/6233/5716/23493/7311/5694/3516/4851/5693/5663/5721/5696/5691/7314 67 Human_papillomavirus_type_18 R-HSA-5687128 MAPK6/MAPK4 signaling 70/1364 89/10654 6.623635292224759e-46 2.653727429981661e-44 1.1740365441566465e-44 5718/5689/27161/3725/5684/5720/2309/5682/5700/10642/122706/5707/5690/57690/5717/9491/3315/23198/27327/143471/5706/5705/10197/3337/192670/8550/7316/10213/5709/5695/983/5597/5714/4609/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/8555/5702/192669/998/8556/5719/23112/5704/6233/5716/7514/7311/4343/5694/26523/8202/5693/5721/5696/5691/7314 70 Human_papillomavirus_type_18 R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 56/1364 60/10654 1.0919113013382399e-45 4.237980738319044e-44 1.874926642429478e-44 5718/1017/5689/9134/1019/5684/5720/5682/5700/5707/5690/5717/1027/9491/6500/898/5706/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/595/5699/5710/5702/8900/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 56 Human_papillomavirus_type_18 R-HSA-168273 Influenza Viral RNA Transcription and Replication 87/1364 134/10654 1.7064998945548336e-45 6.422645057688192e-44 2.841444800502785e-44 6158/6138/6144/6203/5434/5440/5903/9349/4736/6194/6191/7175/6128/51121/6132/9631/6147/6129/6217/5430/6230/6222/5436/6152/6136/6125/6224/6154/51065/6141/6202/5441/23636/6232/5438/6134/5431/6160/6164/5435/6155/6175/5433/6218/6209/6193/4927/6210/6231/6229/9688/6205/6165/6130/6142/6204/6228/5437/23521/23225/3320/140801/6156/6143/6181/5439/6124/6207/6233/7311/6223/9972/6188/6189/8021/6396/6135/6201/6161/9045/6187/5432/6168/6208/6137/8480/6122 87 Human_papillomavirus_type_18 R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 51/1364 52/10654 5.931281720407228e-45 2.1666623225722876e-43 9.585538879419732e-44 5718/5689/1019/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/595/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Human_papillomavirus_type_18 R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 53/1364 56/10654 3.740706643290134e-44 1.3274164717046703e-42 5.872628173826918e-43 5718/3303/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/3315/23198/26986/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/3304/3312/5693/5721/5696/5691/7314 53 Human_papillomavirus_type_18 R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 101/1364 182/10654 1.0611089178825187e-43 3.6608257666946896e-42 1.6195872957154235e-42 1912/7020/23468/7150/6670/5903/7068/7175/1487/5241/3622/9631/5468/7021/1029/7486/1788/9112/8535/51564/1786/6045/9212/51588/4869/3090/80012/7153/6613/23636/332/5885/10210/28996/1655/5970/4792/3190/6996/9759/9612/8856/1911/6790/641/6672/5111/2099/4927/9688/9656/7341/1387/84733/10521/1616/23225/2908/2033/23512/8243/9126/57332/7022/142/7428/3066/3065/7157/1107/6256/7329/5987/5371/8924/672/115426/7158/10155/367/9972/10499/6612/9063/7155/5914/25942/8021/6117/6294/6396/648/11315/8648/7421/8480/10891/7508/6015/4193/8554 101 Human_papillomavirus_type_18 R-HSA-69242 S Phase 94/1364 161/10654 2.664885132494563e-43 8.945371174481748e-42 3.957525004728768e-42 5718/1017/6118/5689/9134/1019/5684/5720/902/5682/1763/7027/5700/122706/7321/5707/207/5690/5717/1027/5982/9491/23198/6500/898/5925/143471/5706/5705/10197/91768/5934/5885/7316/10213/5709/5422/9978/1869/5695/890/4331/1026/84515/5714/5111/4609/9861/5715/6119/5711/5928/2932/5701/5688/5687/6502/5685/5683/5698/5708/10000/5692/5985/5686/5713/1874/8243/9126/595/5699/5710/5702/8900/5984/5719/208/5704/6233/5716/51343/7311/5983/6117/5981/5694/10714/7465/1022/5693/5721/5696/5691/7314 94 Human_papillomavirus_type_18 R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 52/1364 55/10654 2.860484569140383e-43 9.349267986506199e-42 4.136213144297174e-42 5718/5689/8945/5684/5720/5682/5700/122706/5707/991/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/51343/7311/5694/5693/5721/5696/5691/7314 52 Human_papillomavirus_type_18 R-HSA-8939902 Regulation of RUNX2 expression and activity 61/1364 73/10654 4.1749796886227145e-43 1.3295704546844645e-41 5.882157617978562e-42 57154/5718/5689/7291/5684/5720/5682/5700/122706/5707/10273/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/6772/2099/9861/5715/5711/2932/5701/5688/5687/6502/2908/5685/5683/5698/5708/5692/5686/5713/55294/5699/5710/5702/5719/5704/6233/5716/7311/860/5694/5693/5721/5696/5691/10891/7314 61 Human_papillomavirus_type_18 R-HSA-2990846 SUMOylation 102/1364 188/10654 6.474030917942734e-43 1.9950403468660197e-41 8.826265455242499e-42 1912/7020/23468/7150/6670/5903/7068/29843/7175/1487/5241/3622/9631/5468/7021/1029/7486/1788/9112/8535/51564/1786/6045/9212/51588/4869/3090/80012/7153/6613/23636/332/5885/10210/28996/1655/5970/4792/3190/6996/9759/9612/8856/1911/6790/641/6672/5111/2099/4927/9688/9656/7341/1387/84733/10521/1616/23225/2908/2033/23512/8243/9126/57332/7022/142/7428/3066/3065/7157/1107/6256/7329/5987/5371/8924/672/115426/7158/10155/367/9972/10499/6612/9063/7155/5914/25942/8021/6117/6294/6396/648/11315/8648/7421/8480/10891/7508/6015/4193/8554 102 Human_papillomavirus_type_18 R-HSA-8948751 Regulation of PTEN stability and activity 59/1364 69/10654 6.585881982407955e-43 1.9950403468660197e-41 8.826265455242499e-42 5718/5689/5684/5720/5682/1459/5700/122706/5707/10273/207/5690/5717/9491/23198/1460/143471/5706/5705/10197/7316/10213/5709/5695/1457/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/10000/5692/5686/5713/5728/5699/5710/5702/5719/5987/208/5704/6233/5716/7311/331/5694/5693/5721/5696/23608/5691/7314 59 Human_papillomavirus_type_18 R-HSA-1169091 Activation of NF-kappaB in B cells 58/1364 67/10654 7.64189671025935e-43 2.2598180271766935e-41 9.9976693803393e-42 1147/5718/5689/8945/5684/5720/4790/5966/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5970/4792/4793/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/3551/5693/5721/5696/5691/7314 58 Human_papillomavirus_type_18 R-HSA-180534 Vpu mediated degradation of CD4 50/1364 52/10654 1.072241398352114e-42 2.833454929262395e-41 1.2535498542884737e-41 5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Human_papillomavirus_type_18 R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/1364 52/10654 1.072241398352114e-42 2.833454929262395e-41 1.2535498542884737e-41 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/472/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Human_papillomavirus_type_18 R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 50/1364 52/10654 1.072241398352114e-42 2.833454929262395e-41 1.2535498542884737e-41 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Human_papillomavirus_type_18 R-HSA-69610 p53-Independent DNA Damage Response 50/1364 52/10654 1.072241398352114e-42 2.833454929262395e-41 1.2535498542884737e-41 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Human_papillomavirus_type_18 R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 50/1364 52/10654 1.072241398352114e-42 2.833454929262395e-41 1.2535498542884737e-41 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Human_papillomavirus_type_18 R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 51/1364 54/10654 2.1836902914483627e-42 5.534986412201768e-41 2.448735407381408e-41 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/6790/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Human_papillomavirus_type_18 R-HSA-9604323 Negative regulation of NOTCH4 signaling 51/1364 54/10654 2.1836902914483627e-42 5.534986412201768e-41 2.448735407381408e-41 5718/5689/5684/5720/5682/5700/5707/207/5690/5717/9491/6500/5706/5705/10197/7534/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/4855/55294/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Human_papillomavirus_type_18 R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 54/1364 60/10654 5.668017638748522e-42 1.3803290014364047e-40 6.106718694379213e-41 1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5970/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 54 Human_papillomavirus_type_18 R-HSA-5610780 Degradation of GLI1 by the proteasome 54/1364 60/10654 5.668017638748522e-42 1.3803290014364047e-40 6.106718694379213e-41 5718/5689/8945/5684/5720/2735/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/8650/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/83737/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 54 Human_papillomavirus_type_18 R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 62/1364 77/10654 6.695603623027766e-42 1.5992191730385547e-40 7.075111520689259e-41 5718/5689/5684/5720/5682/51512/5700/122706/5707/51807/5690/5717/9491/23198/7277/143471/5706/5705/10197/7316/10213/5709/891/5695/983/1026/5714/9861/5715/5711/5701/5688/5687/7846/5685/5683/5698/5708/3320/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/3326/5716/7311/10383/5347/84790/5694/5693/5721/5696/7280/5691/7314 62 Human_papillomavirus_type_18 R-HSA-8941858 Regulation of RUNX3 expression and activity 51/1364 55/10654 2.637862368176117e-41 6.181556719386297e-40 2.7347848186453484e-40 57154/5718/5689/5684/5720/5682/1029/864/5700/5707/5690/5717/9491/5706/5705/10197/7316/10213/5709/5695/5714/6714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/2033/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314/4193 51 Human_papillomavirus_type_18 R-HSA-4641258 Degradation of DVL 52/1364 57/10654 3.5238852980832405e-41 8.104936185591453e-40 3.585707847172421e-40 5718/5689/5684/5720/5682/5700/122706/5707/1856/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/1855/5716/23072/7311/5694/5693/5721/5696/5691/7314 52 Human_papillomavirus_type_18 R-HSA-5676590 NIK-->noncanonical NF-kB signaling 53/1364 59/10654 4.1238437552150684e-41 9.3123889890493e-40 4.119897493248356e-40 1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 53 Human_papillomavirus_type_18 R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 64/1364 83/10654 4.3809438648628585e-41 9.716307643142268e-40 4.298595295974459e-40 1147/5718/5689/8945/5684/4893/5720/4790/5966/5682/4772/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/5530/7316/10213/5709/5695/5970/4792/4793/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5534/5699/5710/5702/5719/5704/6233/5716/7311/3845/5694/3265/3551/5693/5721/5696/5691/7314 64 Human_papillomavirus_type_18 R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 66/1364 88/10654 5.327479407084598e-41 1.1608297234384334e-39 5.135631118186814e-40 5718/3303/5689/5684/5720/5682/5700/122706/5707/207/5690/5717/9491/3315/23198/26986/143471/5706/5705/10197/7534/7316/10213/5709/5695/5714/9861/5715/5711/1432/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5580/5716/7514/7311/11340/8021/5600/5694/3304/3312/6418/23016/5693/54512/5721/5696/5691/7529/7314/1994 66 Human_papillomavirus_type_18 R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 48/1364 50/10654 6.437305289563716e-41 1.3784712361445061e-039 6.0984997480077304e-40 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 48 Human_papillomavirus_type_18 R-HSA-72689 Formation of a pool of free 40S subunits 71/1364 101/10654 7.267717857556169e-41 1.529916199844875e-39 6.768507977955969e-40 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/8666/6129/6217/6230/6222/6152/6136/8668/8667/6125/6224/6154/51065/8662/6141/10480/6202/6232/6134/6160/6164/6155/6175/6218/6209/6193/6210/6231/6229/6205/6165/6130/6142/6204/6228/23521/140801/6156/6143/6181/6124/6207/6233/7311/6223/3646/51386/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6137/6122 71 Human_papillomavirus_type_18 R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 65/1364 86/10654 9.35741094490403e-41 1.9052302284542305e-39 8.428936174702165e-40 5718/1017/5689/8945/5684/5720/5682/5700/122706/7321/5707/991/5690/9212/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/891/5695/890/983/6790/5714/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/8556/5719/9232/5704/6233/5716/701/51343/7311/5347/5694/5693/5721/5696/5691/7314 65 Human_papillomavirus_type_18 R-HSA-453276 Regulation of mitotic cell cycle 65/1364 86/10654 9.35741094490403e-41 1.9052302284542305e-39 8.428936174702165e-40 5718/1017/5689/8945/5684/5720/5682/5700/122706/7321/5707/991/5690/9212/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/891/5695/890/983/6790/5714/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/8556/5719/9232/5704/6233/5716/701/51343/7311/5347/5694/5693/5721/5696/5691/7314 65 Human_papillomavirus_type_18 R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 51/1364 56/10654 2.5955304259740014e-40 5.199433530741467e-39 2.3002833316781472e-39 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/84447/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 51 Human_papillomavirus_type_18 R-HSA-1234174 Cellular response to hypoxia 60/1364 75/10654 2.853292225884119e-40 5.625061816742978e-39 2.488585700771111e-39 5718/5689/5684/5720/5682/112399/5700/122706/7321/5707/7422/5690/5717/9491/23198/3091/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/10370/5701/5688/1387/5687/5685/5683/5698/5708/5692/5686/5713/2033/5699/5710/7428/5702/5719/5704/6233/5716/7311/55662/5694/405/5693/5721/5696/5691/768/7314 60 Human_papillomavirus_type_18 R-HSA-5610783 Degradation of GLI2 by the proteasome 53/1364 60/10654 3.1055733118219458e-40 5.934033928127471e-39 2.6252781680502926e-39 5718/5689/8945/5684/5720/5682/5700/122706/5707/1452/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 53 Human_papillomavirus_type_18 R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 53/1364 60/10654 3.1055733118219458e-40 5.934033928127471e-39 2.6252781680502926e-39 5718/5689/8945/5684/5720/5682/5700/122706/5707/1452/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 53 Human_papillomavirus_type_18 R-HSA-73894 DNA Repair 138/1364 334/10654 3.195332668623125e-40 6.013035112772607e-39 2.6602291116766684e-39 9318/8467/1017/6118/2176/80010/25/3838/5434/5440/4436/83990/902/5888/9156/2074/5883/1763/328/7486/5430/10111/4913/5436/7320/51588/7520/51720/675/2956/7515/5982/63967/9557/5531/51548/4292/11200/545/472/6613/5441/7706/7336/86/5438/580/5431/11073/5591/8450/5435/7316/9978/5433/11201/116028/890/6996/4331/641/5111/9100/1643/7415/5395/64421/9656/6119/51455/3364/22976/7341/10524/4683/5437/144715/1161/1642/2965/5985/25898/2033/84126/142/7398/2068/5439/1111/10987/2071/7157/8900/5984/4595/7329/4255/79728/8924/57599/6233/2067/51426/2873/2968/672/5932/7158/7311/6047/4968/79184/6612/55247/60/7156/5983/6117/5599/7334/5981/10714/7874/2547/5884/5810/1022/5432/8178/83695/5886/7508/7314/51514/51138/8451/8554/7528 138 Human_papillomavirus_type_18 R-HSA-453274 Mitotic G2-G2/M phases 102/1364 198/10654 3.264011678346623e-40 6.050600752994784e-39 2.6768485406079137e-39 10844/115106/5718/1017/5689/8945/22995/5684/5720/902/2305/5682/22981/7531/51512/4659/5700/122706/5707/203068/51807/7532/1454/22974/5690/5717/9491/23198/6500/7277/143471/5706/5705/10197/7316/10213/5709/9978/1869/891/5695/890/4331/983/1026/6790/5714/9861/5715/5519/5711/5928/5701/5688/5687/23291/7846/5685/7283/5683/5698/5708/3320/5692/5686/5713/80097/2033/995/5699/5710/5702/10540/7157/8900/5719/5704/6233/3326/5716/7514/7311/54930/5518/10383/55835/5347/84790/9662/5694/1453/7465/1022/8481/5693/5721/5696/7280/5691/7314/5515/5516 102 Human_papillomavirus_type_18 R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 47/1364 49/10654 4.976849341616545e-40 9.030060229139556e-39 3.9949923210533504e-39 1017/9134/1820/57060/7027/25946/7832/4849/1027/4869/898/4850/2810/9337/5934/1869/891/890/10769/983/1026/6790/5933/5111/25904/246175/1647/4848/23019/28984/2033/995/1874/7157/8900/10498/55571/55835/5325/581/57472/3276/144455/85456/79733/29883/1263 47 Human_papillomavirus_type_18 R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 74/1364 111/10654 5.016700127299753e-40 9.030060229139556e-39 3.9949923210533504e-39 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/8666/6129/6217/6230/6222/6152/6136/8668/8667/6125/6224/6154/51065/8662/6141/10480/26986/6202/6232/6134/6160/6164/6155/6175/6218/6209/6193/6210/6231/6229/6205/6165/6130/6142/6204/6228/23521/8894/140801/6156/6143/1973/6181/6124/6207/6233/7311/6223/3646/51386/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6137/6122 74 Human_papillomavirus_type_18 R-HSA-69275 G2/M Transition 101/1364 196/10654 7.715934078875464e-40 1.3690271608519037e-38 6.056718179207507e-39 10844/115106/5718/1017/5689/8945/22995/5684/5720/902/2305/5682/22981/7531/51512/4659/5700/122706/5707/203068/51807/7532/1454/22974/5690/5717/9491/23198/6500/7277/143471/5706/5705/10197/7316/10213/5709/9978/891/5695/890/4331/983/1026/6790/5714/9861/5715/5519/5711/5928/5701/5688/5687/23291/7846/5685/7283/5683/5698/5708/3320/5692/5686/5713/80097/2033/995/5699/5710/5702/10540/7157/8900/5719/5704/6233/3326/5716/7514/7311/54930/5518/10383/55835/5347/84790/9662/5694/1453/7465/1022/8481/5693/5721/5696/7280/5691/7314/5515/5516 101 Human_papillomavirus_type_18 R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 74/1364 112/10654 1.3002841532417238e-39 2.2745815751073533e-38 1.006298484791964e-38 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/8666/6129/6217/6230/6222/6152/6136/8668/8667/6125/6224/6154/51065/8662/6141/10480/6202/6232/6134/6160/6164/6155/6175/6218/9669/6209/6193/6210/6231/6229/6205/6165/6130/6142/6204/6228/23521/8894/140801/6156/6143/1973/6181/6124/6207/6233/7311/6223/3646/51386/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6137/6122 74 Human_papillomavirus_type_18 R-HSA-156902 Peptide chain elongation 65/1364 89/10654 3.566068154037542e-39 6.15146756571476e-38 2.7214730649233876e-38 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/1938/6147/6129/1915/6217/6230/6222/6152/6136/6125/6224/6154/51065/6141/6202/6232/6134/6160/6164/6155/6175/6218/6209/6193/6210/6231/6229/6205/6165/6130/6142/6204/6228/23521/140801/6156/6143/6181/6124/6207/6233/7311/6223/6188/6189/6135/6201/6161/9045/6187/6168/6208/6137/6122 65 Human_papillomavirus_type_18 R-HSA-195253 Degradation of beta-catenin by the destruction complex 62/1364 82/10654 6.180173004991384e-39 1.0514760098903149e-37 4.651838945357609e-38 5718/5689/8945/5684/5720/1487/5682/1499/5700/122706/5707/1452/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5519/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/8312/5710/5702/3065/5719/5704/6233/5527/5716/7311/5518/5694/5693/5721/5696/5691/7314/5515/5516 62 Human_papillomavirus_type_18 R-HSA-180585 Vif-mediated degradation of APOBEC3G 49/1364 54/10654 1.398017631232988e-38 2.3464025648532043e-37 1.0380728357092743e-37 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 49 Human_papillomavirus_type_18 R-HSA-5607764 CLEC7A (Dectin-1) signaling 69/1364 101/10654 1.8744152245950988e-38 3.1040316119294834e-37 1.3732557855980934e-37 1147/5718/5689/8945/5684/5720/4790/5682/4772/5700/122706/7321/5707/5336/5690/5717/9491/23198/6500/143471/5706/5705/841/10197/5530/7316/10213/5709/5695/5970/4792/6850/5714/6714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5534/5699/5710/10454/5702/9040/5719/7189/5704/6233/5580/5716/7311/7334/5694/3551/5693/5721/5696/5691/7314 69 Human_papillomavirus_type_18 R-HSA-72613 Eukaryotic Translation Initiation 75/1364 119/10654 5.445835776200974e-38 8.784062381872221e-37 3.886160321499534e-37 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/8666/6129/6217/6230/6222/6152/6136/8668/8667/6125/6224/6154/51065/8662/6141/10480/26986/6202/6232/6134/6160/6164/6155/6175/6218/9669/6209/6193/6210/6231/6229/6205/6165/6130/6142/6204/6228/23521/8894/140801/6156/6143/1973/6181/6124/6207/6233/7311/6223/3646/51386/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6137/6122 75 Human_papillomavirus_type_18 R-HSA-72737 Cap-dependent Translation Initiation 75/1364 119/10654 5.445835776200974e-38 8.784062381872221e-37 3.886160321499534e-37 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/8666/6129/6217/6230/6222/6152/6136/8668/8667/6125/6224/6154/51065/8662/6141/10480/26986/6202/6232/6134/6160/6164/6155/6175/6218/9669/6209/6193/6210/6231/6229/6205/6165/6130/6142/6204/6228/23521/8894/140801/6156/6143/1973/6181/6124/6207/6233/7311/6223/3646/51386/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6137/6122 75 Human_papillomavirus_type_18 R-HSA-5387390 Hh mutants abrogate ligand secretion 51/1364 59/10654 1.0216337996408495e-37 1.6070586689942203e-36 7.109794264047655e-37 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/84447/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 51 Human_papillomavirus_type_18 R-HSA-169911 Regulation of Apoptosis 48/1364 53/10654 1.022203179150913e-37 1.6070586689942203e-36 7.109794264047655e-37 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 48 Human_papillomavirus_type_18 R-HSA-4641257 Degradation of AXIN 49/1364 55/10654 1.125760477409258e-37 1.747743141177873e-36 7.732196963258325e-37 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/8312/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 49 Human_papillomavirus_type_18 R-HSA-2871837 FCERI mediated NF-kB activation 61/1364 82/10654 1.3022044529177122e-37 1.9967134944738254e-36 8.833667633827755e-37 1147/5718/5689/8945/5684/5720/4790/5682/5700/122706/7321/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5970/4792/5714/9861/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/10454/5702/5719/7189/5704/6233/5716/7311/7334/5694/3551/5693/5721/5696/5691/7314 61 Human_papillomavirus_type_18 R-HSA-157118 Signaling by NOTCH 109/1364 235/10654 1.9878481452040854e-37 3.0108626784676514e-36 1.3320368829223782e-36 5718/5689/27161/3725/5684/8841/5720/79718/79885/5682/2648/9734/7027/55869/5700/5707/23462/207/51564/4904/5690/55534/57690/5717/9491/6500/27327/84441/3091/51548/10013/5706/5705/10197/10046/192670/7534/488/7316/10213/5709/83933/9978/1950/1869/4854/9611/5695/8650/9759/9612/1024/5714/6772/4609/9861/10014/5715/22938/8850/5711/5087/5701/5688/1387/5687/4088/5685/6907/5683/5698/5708/59/5692/5686/5713/2033/4855/595/55294/5699/5710/5702/192669/3066/3065/7157/83737/5719/23112/9794/5704/6233/5716/1385/23493/7311/1956/4343/5694/26523/3516/4851/5693/5663/5721/5696/5691/7314 109 Human_papillomavirus_type_18 R-HSA-8878171 Transcriptional regulation by RUNX1 110/1364 239/10654 2.2535210849155596e-37 3.372136370439909e-36 1.4918681120176567e-36 55904/1912/5718/9070/5689/27161/25/5684/5720/902/11091/6597/5682/1459/5700/122706/5707/8535/8085/6045/5690/57690/5717/5929/9491/23198/27327/80012/1460/143471/5706/6598/5705/10197/6599/192670/86/7316/10213/5709/5695/28996/10398/1457/4331/1911/6603/5714/23309/6714/2099/9861/5715/8850/5711/5701/5688/1387/84733/5687/5685/5683/8289/5698/5708/5692/5686/5713/2033/1021/6602/57332/595/50943/5699/4602/8312/5710/5702/192669/3065/83737/5719/5371/23112/5704/6233/5716/7311/7161/860/58508/25942/9739/4343/648/3276/5694/23466/26523/7057/1022/5693/5721/23429/4297/5696/5691/7314/6015 110 Human_papillomavirus_type_18 R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 60/1364 80/10654 2.3191615740063435e-37 3.429046041566522e-36 1.5170455408913675e-36 5718/1017/5689/8945/5684/5720/5682/5700/122706/7321/5707/991/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/891/5695/890/983/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/5719/5704/6233/5716/701/51343/7311/5347/5694/5693/5721/5696/5691/7314 60 Human_papillomavirus_type_18 R-HSA-156842 Eukaryotic Translation Elongation 65/1364 93/10654 3.0357475081665156e-37 4.435762829579779e-36 1.962427491347271e-36 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/1938/6147/6129/1915/6217/6230/6222/6152/6136/6125/6224/6154/51065/6141/6202/6232/6134/6160/6164/6155/6175/6218/6209/6193/6210/6231/6229/6205/6165/6130/6142/6204/6228/23521/140801/6156/6143/6181/6124/6207/6233/7311/6223/6188/6189/6135/6201/6161/9045/6187/6168/6208/6137/6122 65 Human_papillomavirus_type_18 R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 79/1364 134/10654 6.124050559549753e-37 8.844268366233481e-36 3.912796073543417e-36 1147/5718/5689/3725/8945/5684/5601/4893/5290/5720/4790/5682/4772/5700/122706/7321/5707/5336/5690/5594/5717/4214/9491/23198/6500/143471/5706/5705/10197/5530/7316/10213/5709/5695/5970/4792/6850/5714/9861/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5602/5692/5686/5713/5534/5699/5710/10454/5702/5719/7189/5609/5704/6233/5716/2353/7311/3845/5599/7334/5694/3265/3551/5693/5721/5696/5691/7314/5595 79 Human_papillomavirus_type_18 R-HSA-192823 Viral mRNA Translation 63/1364 89/10654 1.1658972593028196e-36 1.6644188460391978e-35 7.36356163770202e-36 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/6152/6136/6125/6224/6154/51065/6141/6202/6232/6134/6160/6164/6155/6175/6218/6209/6193/6210/6231/6229/6205/6165/6130/6142/6204/6228/23521/140801/6156/6143/6181/6124/6207/6233/7311/6223/6188/6189/6135/6201/6161/9045/6187/6168/6208/6137/6122 63 Human_papillomavirus_type_18 R-HSA-9020702 Interleukin-1 signaling 68/1364 103/10654 1.916325707433646e-36 2.704632418900669e-35 1.1965574393305782e-35 1147/5718/5689/8945/5684/351/5720/4790/5682/5700/122706/5707/5690/8878/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/5970/4792/4793/5714/3146/9861/5715/5711/3552/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/57162/5710/10454/5702/5719/7189/6285/5704/6233/5716/7311/7334/5694/3551/57161/5693/5721/5696/5691/7314 68 Human_papillomavirus_type_18 R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 56/1364 72/10654 1.9526481417420475e-36 2.724931451734408e-35 1.205537942033529e-35 5718/5689/5684/5720/5682/5700/122706/7321/5707/991/5690/9212/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/6790/5714/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/9232/5704/6233/5716/51343/7311/5347/5694/5693/5721/5696/5691/7314 56 Human_papillomavirus_type_18 R-HSA-5658442 Regulation of RAS by GAPs 54/1364 68/10654 4.9545607591202165e-36 6.837293847585899e-35 3.0248897266207637e-35 5718/5689/5684/4893/5720/5682/153090/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/3845/5694/3265/4763/5693/5721/5696/5691/7314 54 Human_papillomavirus_type_18 R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 53/1364 66/10654 7.562323981391213e-36 1.0321325697678995e-34 4.566261559613896e-35 5718/5689/5684/5720/5682/112399/5700/122706/7321/5707/5690/5717/9491/23198/3091/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/7428/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 53 Human_papillomavirus_type_18 R-HSA-68949 Orc1 removal from chromatin 55/1364 71/10654 1.2287963115027508e-35 1.6588750205287135e-34 7.339035178540457e-35 5718/1017/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/890/84515/5714/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 55 Human_papillomavirus_type_18 R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 57/1364 76/10654 1.520289250824863e-35 2.0303217736822363e-34 8.982354147488155e-35 5718/5689/5684/5720/5682/5700/122706/7321/5707/991/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/891/5695/890/983/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/5719/9232/5704/6233/5716/701/7311/5347/5694/5693/5721/5696/5691/7314 57 Human_papillomavirus_type_18 R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 64/1364 95/10654 3.6078770586406974e-35 4.767003517906113e-34 2.1089718080744058e-34 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/6152/6136/6125/6224/6154/51065/6141/26986/6202/6232/6134/6160/6164/6155/6175/6218/6209/6193/6210/6231/6229/6205/6165/6130/6142/6204/6228/23521/140801/6156/6143/6181/6124/6207/6233/7311/6223/6188/6189/6135/6201/6161/9045/6187/6168/6208/6137/6122 64 Human_papillomavirus_type_18 R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 55/1364 72/10654 4.5725746852127006e-035 5.978039746351762e-34 2.644746798538537e-34 5718/1017/5689/9134/5684/5720/5682/5700/122706/7321/5707/5690/5717/9491/23198/898/143471/5706/5705/10197/7316/10213/5709/5695/890/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/5719/5704/6233/5716/51343/7311/5694/5693/5721/5696/5691/7314 55 Human_papillomavirus_type_18 R-HSA-2408557 Selenocysteine synthesis 63/1364 93/10654 7.411567442743399e-35 9.489862643182785e-34 4.19841367890619e-34 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/6152/6136/6125/6224/6154/51065/6141/6202/6232/6134/6160/6164/6155/6175/6218/6209/6193/6210/6231/6229/6205/6165/6130/6142/6204/6228/23521/140801/6156/6143/6181/6124/6207/6233/7311/6223/6188/6189/6135/6201/6161/9045/6187/6168/6208/6137/6122 63 Human_papillomavirus_type_18 R-HSA-72764 Eukaryotic Translation Termination 63/1364 93/10654 7.411567442743399e-35 9.489862643182785e-34 4.19841367890619e-34 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/6152/6136/6125/6224/6154/51065/6141/6202/6232/6134/6160/6164/6155/6175/6218/6209/6193/6210/6231/6229/6205/6165/6130/6142/6204/6228/23521/140801/6156/6143/6181/6124/6207/6233/7311/6223/6188/6189/6135/6201/6161/9045/6187/6168/6208/6137/6122 63 Human_papillomavirus_type_18 R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 56/1364 75/10654 9.230107775678662e-35 1.1697748834074385e-33 5.175205433839164e-34 5718/5689/5684/5720/5682/5700/122706/7321/5707/991/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/891/5695/890/983/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/5719/9232/5704/6233/5716/701/7311/5694/5693/5721/5696/5691/7314 56 Human_papillomavirus_type_18 R-HSA-5678895 Defective CFTR causes cystic fibrosis 50/1364 61/10654 1.0535095571390401e-34 1.3216756262289776e-33 5.8472300779008926e-34 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Human_papillomavirus_type_18 R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 49/1364 59/10654 1.452864036817427e-34 1.8044571337272442e-33 7.983105549670494e-34 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/84515/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 49 Human_papillomavirus_type_18 R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 45/1364 51/10654 2.9365963438375397e-34 3.61114124658042e-33 1.597606348601559e-33 5718/5689/5684/1728/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/5694/5693/5721/5696/5691 45 Human_papillomavirus_type_18 R-HSA-5688426 Deubiquitination 120/1364 297/10654 7.3042002604238916e-34 8.893937964163208e-33 3.934770418928041e-33 9960/5718/23358/5689/5684/8295/5720/3607/10617/221937/5682/2648/79594/5700/10474/122706/7321/5707/991/8237/4738/5690/55611/4303/51720/5717/9491/57646/23198/63967/4086/1080/3091/143471/5706/5705/4287/27005/10197/7706/86/580/7316/10213/5709/5695/890/7417/25862/4792/983/84132/5714/4092/8678/2099/9100/1643/79589/4609/7415/9861/4194/4089/5715/64426/8850/7128/5711/5701/5688/5687/6502/4088/5685/5683/5698/5708/5692/5686/5713/2033/5728/5699/8312/5710/10454/5702/7157/8900/9958/4087/5719/7189/57599/5704/6233/5716/672/7311/55593/367/6881/79184/51616/78990/60/7345/1540/5694/7874/5693/10254/5721/5696/5691/5886/7314/4193/7528 120 Human_papillomavirus_type_18 R-HSA-69239 Synthesis of DNA 71/1364 119/10654 9.053025425883551e-34 1.0916366581502302e-32 4.829513819428936e-33 5718/1017/6118/5689/9134/5684/5720/5682/1763/5700/122706/7321/5707/5690/5717/5982/9491/23198/6500/898/143471/5706/5705/10197/7316/10213/5709/5422/9978/5695/890/84515/5714/5111/9861/5715/6119/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5985/5686/5713/5699/5710/5702/8900/5984/5719/5704/6233/5716/51343/7311/5983/6117/5981/5694/10714/5693/5721/5696/5691/7314 71 Human_papillomavirus_type_18 R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 54/1364 72/10654 9.925000021013544e-34 1.1852740409710405e-32 5.243775314746023e-33 5718/5689/5684/5720/5682/5700/122706/7321/5707/991/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/890/983/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/5719/5704/6233/5716/701/7311/5694/5693/5721/5696/5691/7314 54 Human_papillomavirus_type_18 R-HSA-449147 Signaling by Interleukins 157/1364 461/10654 1.1207096403827715e-33 1.3256394031956214e-32 5.864766238394052e-33 7124/1147/5718/834/5689/3725/7291/8945/596/5684/5601/351/5290/5720/4790/6627/6597/5606/2309/5682/5700/122706/7184/5707/27250/207/7422/5690/5594/8878/4582/5717/9491/23198/6500/5908/5743/3091/143471/4318/5706/4312/3383/5705/58480/301/6097/10197/6657/6778/3576/7534/3313/332/6776/4313/7316/10213/5709/6175/9978/5695/3185/6774/5970/4792/4205/6850/1026/4793/5714/6772/8651/4609/3146/9861/5715/5519/5898/5711/5598/3552/1432/4208/5701/5688/79923/5687/6950/4067/3717/23291/4088/598/2247/836/5685/5683/5698/5708/3320/5602/5692/5686/5713/595/6195/5699/57162/5710/3181/10454/5702/998/7157/6648/5719/7189/6285/5609/5704/6233/1398/5716/1385/2353/604/6196/7311/6347/5518/302/1386/6197/5599/5600/7431/4282/6777/7334/5694/3312/3551/3569/3162/57161/4170/5693/5721/5696/5691/51231/4692/7314/5595/5515/5516 157 Human_papillomavirus_type_18 R-HSA-5358346 Hedgehog ligand biogenesis 51/1364 65/10654 1.2916893086707275e-33 1.5134699258198524e-32 6.695747955572192e-33 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/84447/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 51 Human_papillomavirus_type_18 R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 44/1364 50/10654 2.0824259705143616e-33 2.4171710797933057e-32 1.0693815608543992e-32 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/5694/5693/5721/5696/5691 44 Human_papillomavirus_type_18 R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 54/1364 73/10654 3.350220203795534e-33 3.852753234364864e-32 1.7044979984222892e-32 5718/5689/5684/5720/5682/5700/122706/7321/5707/991/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/890/983/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/5719/5704/6233/5716/701/7311/5694/5693/5721/5696/5691/7314 54 Human_papillomavirus_type_18 R-HSA-4608870 Asymmetric localization of PCP proteins 50/1364 64/10654 8.1745433439488e-33 9.314479663471936e-32 4.1208224293010856e-32 57154/5718/5689/5684/5720/5682/5700/122706/5707/1856/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Human_papillomavirus_type_18 R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 51/1364 67/10654 1.8366597280478418e-32 2.0737558020321997e-31 9.174510794650465e-32 5718/5689/5684/5720/5682/5700/122706/7321/5707/991/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/9232/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Human_papillomavirus_type_18 R-HSA-69306 DNA Replication 72/1364 127/10654 3.305953433751259e-32 3.6990938420892464e-31 1.6365174892538239e-31 5718/1017/6118/5689/9134/5684/5720/5682/1763/5700/122706/7321/5707/5690/5717/5982/9491/23198/6500/898/143471/5706/5705/10197/7316/10213/5709/5422/9978/1869/5695/890/84515/5714/5111/9861/5715/6119/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5985/5686/5713/5699/5710/5702/8900/5984/5719/5704/6233/5716/51343/7311/5983/6117/5981/5694/10714/5693/5721/5696/5691/7314 72 Human_papillomavirus_type_18 R-HSA-927802 Nonsense-Mediated Decay (NMD) 68/1364 115/10654 4.8145532009184074e-32 5.291747854460763e-31 2.341124146138247e-31 6158/9887/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/6152/6136/6125/6224/6154/51065/6141/26986/6202/6232/6134/6160/6164/6155/6175/6218/6209/6193/6210/6231/6229/6205/6165/6130/6142/6204/6228/23521/140801/6156/6143/6181/6124/6207/6233/23381/7311/6223/5518/6188/6189/6135/6201/6161/9045/6187/6168/6208/6137/6122/5515 68 Human_papillomavirus_type_18 R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 68/1364 115/10654 4.8145532009184074e-32 5.291747854460763e-31 2.341124146138247e-31 6158/9887/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/6152/6136/6125/6224/6154/51065/6141/26986/6202/6232/6134/6160/6164/6155/6175/6218/6209/6193/6210/6231/6229/6205/6165/6130/6142/6204/6228/23521/140801/6156/6143/6181/6124/6207/6233/23381/7311/6223/5518/6188/6189/6135/6201/6161/9045/6187/6168/6208/6137/6122/5515 68 Human_papillomavirus_type_18 R-HSA-983705 Signaling by the B Cell Receptor (BCR) 67/1364 112/10654 5.033898693690217e-32 5.484300155757237e-31 2.4263112817232627e-31 1147/5718/5689/8945/5684/4893/5720/4790/5966/5682/4772/5700/122706/5707/5336/5690/5717/9491/23198/6500/143471/5706/5705/10197/5530/7316/10213/5709/5695/5970/4792/6850/4793/5714/9861/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/5534/5699/5710/5702/5719/5704/6233/5716/7311/3845/5694/3265/3551/5693/5721/5696/5691/7314 67 Human_papillomavirus_type_18 R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 40/1364 44/10654 9.559465740834378e-32 1.032422300010113e-30 4.567543356261369e-31 23368/834/27113/79370/9540/8793/55240/58484/3486/355/55367/472/8794/332/64065/5366/124446/8797/84883/147923/5876/1387/51499/843/94241/7157/8626/604/63970/7161/839/581/7159/637/317/10397/8795/665/5875/27166 40 Human_papillomavirus_type_18 R-HSA-5621481 C-type lectin receptors (CLRs) 76/1364 142/10654 1.2226698748033457e-31 1.3090999866428927e-30 5.791594143805323e-31 1147/5718/5689/8945/5684/4893/5720/4790/5682/4772/5700/122706/7321/5707/5336/5690/4582/5717/9491/23198/6500/143471/5706/5705/841/10197/5530/7316/10213/5709/5695/5970/4792/6850/5714/6714/9861/5715/5711/5701/5688/1387/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/2033/5534/5699/5710/10454/5702/9040/5719/7189/5704/6233/5580/5716/7311/3845/7334/5694/3265/3551/5693/5721/5696/5691/7314 76 Human_papillomavirus_type_18 R-HSA-69052 Switching of origins to a post-replicative state 59/1364 90/10654 1.6718718453779626e-31 1.774756266631991e-30 7.851705832544279e-31 5718/1017/5689/9134/5684/5720/5682/5700/122706/7321/5707/5690/5717/9491/23198/6500/898/143471/5706/5705/10197/7316/10213/5709/9978/5695/890/84515/5714/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/5719/5704/6233/5716/51343/7311/5694/5693/5721/5696/5691/7314 59 Human_papillomavirus_type_18 R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 66/1364 112/10654 5.24264022875118e-31 5.5181009865330215e-30 2.4412651199001927e-30 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/6152/6136/6125/6224/6154/51065/6141/6184/6202/6232/6134/6160/6164/6155/6175/6218/29927/6209/6193/6210/6231/6229/6205/6165/6130/6142/6204/6228/23521/140801/6156/6143/6181/6124/6185/6207/6233/7311/6223/6188/6189/6135/6201/6161/9045/6187/6168/6208/6137/6122 66 Human_papillomavirus_type_18 R-HSA-202424 Downstream TCR signaling 61/1364 98/10654 1.2128049638721524e-30 1.26580148330186e-29 5.600037073341562e-30 1147/5718/5689/8945/5684/5290/5720/4790/5682/5700/122706/7321/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5970/4792/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5728/5699/5710/5702/5719/7189/5704/6233/5716/7311/7334/5694/3551/5693/5721/5696/5691/7314 61 Human_papillomavirus_type_18 R-HSA-68867 Assembly of the pre-replicative complex 50/1364 68/10654 1.2954767676323626e-30 1.3408184544994952e-29 5.931919936000818e-30 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/1869/5695/84515/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Human_papillomavirus_type_18 R-HSA-8943724 Regulation of PTEN gene transcription 47/1364 61/10654 2.0102848536767443e-30 2.0634494117905092e-29 9.128914255060988e-30 1912/3725/6591/8841/5468/1822/23186/2146/5978/9112/9219/8535/51564/6045/5594/84232/80012/5931/1911/1108/57167/2122/7101/10014/1958/5928/84733/57459/54815/23512/57332/6615/3066/3065/7157/1107/23028/10542/2475/57504/1386/8726/648/23466/53615/6015/5595 47 Human_papillomavirus_type_18 R-HSA-5689880 Ub-specific processing proteases 96/1364 220/10654 2.165684153143474e-30 2.2047374739378646e-29 9.753987298886052e-30 9960/5718/23358/5689/5684/8295/5720/5682/2648/79594/5700/10474/122706/5707/991/8237/5690/55611/4303/5717/9491/57646/23198/63967/4086/1080/3091/143471/5706/5705/27005/10197/7316/10213/5709/5695/890/7417/25862/4792/84132/5714/4092/8678/9100/1643/79589/4609/9861/4194/4089/5715/64426/5711/5701/5688/5687/6502/4088/5685/5683/5698/5708/5692/5686/5713/5728/5699/8312/5710/10454/5702/7157/8900/9958/4087/5719/7189/57599/5704/6233/5716/7311/367/6881/51616/1540/5694/7874/5693/10254/5721/5696/5691/7314/4193 96 Human_papillomavirus_type_18 R-HSA-351202 Metabolism of polyamines 46/1364 59/10654 3.310450585941127e-30 3.342747664828357e-29 1.4788662437837125e-29 5718/5689/5684/1728/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/6303/5694/5693/5721/5696/5691 46 Human_papillomavirus_type_18 R-HSA-5632684 Hedgehog 'on' state 56/1364 85/10654 3.952902219270916e-30 3.959277868011675e-29 1.7516256014086742e-29 57154/5718/5689/5684/5720/2735/5682/5700/122706/5707/22873/1452/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/9978/5695/8650/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/83737/5719/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 56 Human_papillomavirus_type_18 R-HSA-3247509 Chromatin modifying enzymes 109/1364 274/10654 4.223381404542865e-30 4.163047384477967e-29 1.84177534934952e-29 55904/9643/23774/9070/10196/1019/8295/8841/8464/29943/55167/11091/4790/9869/79718/64769/84148/7862/6597/2648/23186/55869/10474/2146/5978/1788/9112/9219/51147/8085/6839/6871/5929/23569/5931/284058/6598/117143/79813/10629/6599/86/7403/8819/83933/9611/2874/84289/5970/11143/9612/29072/6603/10933/1108/2122/27097/64426/84444/79685/8850/5928/10524/1387/27154/56950/57459/3717/6907/8289/54815/2033/23512/6602/595/7994/3066/3065/1107/79084/23028/23135/55693/10498/57504/80854/6881/58508/10499/57634/1386/6880/51317/10419/60/9739/8726/10902/6883/3276/51230/10284/6187/53615/9913/8648/64754/4297/10919 109 Human_papillomavirus_type_18 R-HSA-4839726 Chromatin organization 109/1364 274/10654 4.223381404542865e-30 4.163047384477967e-29 1.84177534934952e-29 55904/9643/23774/9070/10196/1019/8295/8841/8464/29943/55167/11091/4790/9869/79718/64769/84148/7862/6597/2648/23186/55869/10474/2146/5978/1788/9112/9219/51147/8085/6839/6871/5929/23569/5931/284058/6598/117143/79813/10629/6599/86/7403/8819/83933/9611/2874/84289/5970/11143/9612/29072/6603/10933/1108/2122/27097/64426/84444/79685/8850/5928/10524/1387/27154/56950/57459/3717/6907/8289/54815/2033/23512/6602/595/7994/3066/3065/1107/79084/23028/23135/55693/10498/57504/80854/6881/58508/10499/57634/1386/6880/51317/10419/60/9739/8726/10902/6883/3276/51230/10284/6187/53615/9913/8648/64754/4297/10919 109 Human_papillomavirus_type_18 R-HSA-162909 Host Interactions of HIV factors 70/1364 129/10654 1.0140974308797699e-29 9.917393772855703e-29 4.3875578857790294e-29 5718/5689/8945/3837/5684/5903/5720/7175/5682/9631/3159/5700/122706/5707/5690/5717/4869/9491/23198/6500/143471/5706/5705/23636/10197/7316/10213/5709/9978/5695/292/5714/4927/9688/9861/5715/5711/5701/5688/5687/23225/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5901/5719/5704/6233/5716/7514/1025/7311/9972/8021/6396/5694/1104/5693/5721/5696/5691/8480/7314 70 Human_papillomavirus_type_18 R-HSA-5696398 Nucleotide Excision Repair 64/1364 111/10654 2.4802317377918394e-29 2.406599858076144e-28 1.0647047427034047e-28 9318/6118/5434/5440/902/2074/5430/5436/7515/5982/9557/6613/5441/7336/86/5438/5431/8450/5435/7316/9978/5433/4331/5111/1643/6119/7341/5437/1161/1642/2965/5985/2033/142/2068/5439/10987/2071/5984/7329/6233/2067/51426/2873/2968/7311/6612/60/5983/6117/7334/5981/10714/7874/1022/5432/8178/5886/7508/7314/51138/8451/8554/7528 64 Human_papillomavirus_type_18 R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 47/1364 63/10654 2.5242644974110863e-29 2.430338376577185e-28 1.0752069095459709e-28 5718/5689/5684/5720/5682/5700/7321/5707/5690/5717/9491/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/51343/7311/5694/5693/5721/5696/5691/7314 47 Human_papillomavirus_type_18 R-HSA-69002 DNA Replication Pre-Initiation 55/1364 85/10654 5.242066944071621e-29 5.008190111182272e-28 2.21567525895173e-28 5718/1017/6118/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5422/1869/5695/84515/5714/9861/5715/6119/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/6117/5694/5693/5721/5696/5691/7314 55 Human_papillomavirus_type_18 R-HSA-446652 Interleukin-1 family signaling 72/1364 140/10654 1.4165084121690272e-28 1.3429797312320088e-27 5.941481648471131e-28 1147/5718/834/5689/8945/5684/351/5720/4790/5682/5700/122706/5707/5690/8878/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/6774/5970/4792/4793/5714/3146/9861/5715/5711/3552/5701/5688/5687/23291/4088/5685/5683/5698/5708/5692/5686/5713/5699/57162/5710/10454/5702/5719/7189/6285/5704/6233/5716/7311/5599/7334/5694/3551/57161/5693/5721/5696/5691/7314 72 Human_papillomavirus_type_18 R-HSA-2559583 Cellular Senescence 87/1364 195/10654 1.7605070211678435e-28 1.656477060826107e-27 7.32842635605753e-28 1912/1017/3725/9134/1019/5601/4790/5606/3159/7290/1029/7027/7321/2146/10111/8535/6045/57690/5594/1027/27327/80012/898/5931/7295/5925/1051/472/79813/192670/3576/8550/29855/7316/2114/1869/890/6774/5970/1026/1911/6667/4194/1031/5598/3552/5928/1432/10524/84733/4683/5602/23512/1021/57332/6195/25842/192669/7157/8900/23135/8091/23112/5609/6233/2353/1030/51343/6196/7311/57634/4343/8726/6197/5599/648/5600/23466/26523/2113/3569/10919/7314/23523/6015/5595/4193 87 Human_papillomavirus_type_18 R-HSA-2408522 Selenoamino acid metabolism 65/1364 118/10654 3.47862228947944e-28 3.2484578071680184e-27 1.4371514326143787e-27 6158/6138/6144/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/6152/6136/6125/6224/6154/51065/6141/6202/6232/6134/6160/6164/6155/6175/6218/6209/6193/6210/6231/6229/6205/6165/6130/6142/6204/6228/23521/7965/140801/6156/6143/6181/6124/6207/6233/7311/6223/6188/6189/6135/6201/6161/9045/6187/6168/6208/6137/6122/7296 65 Human_papillomavirus_type_18 R-HSA-5610787 Hedgehog 'off' state 63/1364 113/10654 9.412276832299047e-28 8.723916287847325e-27 3.859551065561747e-27 5718/5689/8945/5684/5720/2735/5682/5700/122706/5707/1452/5690/5717/9491/23198/6500/7277/143471/5706/5705/10197/7316/10213/5709/9978/5695/8650/5714/9861/5715/5711/2932/5701/5688/5687/7846/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/83737/5719/5704/6233/5716/7311/10383/23322/84790/5694/8481/5693/5721/5696/7280/5691/7314 63 Human_papillomavirus_type_18 R-HSA-5685938 HDR through Single Strand Annealing (SSA) 34/1364 37/10654 1.6310408058609126e-27 1.5005575413920394e-26 6.638622227363715e-27 6118/80010/25/83990/5888/9156/5883/1763/7486/10111/5982/545/472/580/11073/116028/641/6119/3364/10524/4683/144715/5985/84126/5984/2067/672/5932/7156/5983/6117/5884/5810/83695 34 Human_papillomavirus_type_18 R-HSA-9614085 FOXO-mediated transcription 46/1364 65/10654 4.627837742342015e-27 4.226304761756458e-26 1.8697610692744053e-26 27113/857/2290/2309/57060/10018/4802/7532/207/10971/4303/23410/1027/7295/2810/4287/6720/7534/5934/4800/1026/901/4089/8850/1647/9314/10370/1387/4088/2908/10628/10000/6794/2033/4801/3630/3066/3065/6648/4087/208/604/23411/25942/7529/10891 46 Human_papillomavirus_type_18 R-HSA-5619084 ABC transporter disorders 50/1364 77/10654 1.388541905173657e-26 1.2588095227924685e-25 5.569103914718779e-26 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Human_papillomavirus_type_18 R-HSA-4086400 PCP/CE pathway 55/1364 92/10654 1.8016240563985677e-26 1.621461650758711e-25 7.173514549504595e-26 57154/5718/5689/5684/5720/5682/5700/122706/5707/1856/5690/1212/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/1855/5716/7311/1213/1211/5694/5693/5721/5696/6259/5691/7314 55 Human_papillomavirus_type_18 R-HSA-5689603 UCH proteinases 58/1364 102/10654 2.974175664309498e-26 2.6575008453758245e-25 1.175705942271532e-25 5718/5689/5684/5720/3607/221937/5682/5700/122706/5707/4738/5690/5717/9491/23198/143471/5706/5705/10197/86/580/7316/10213/5709/5695/5714/4092/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9958/5719/5704/6233/5716/7311/60/7345/5694/5693/5721/5696/5691/7314/7528 58 Human_papillomavirus_type_18 R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 38/1364 47/10654 3.216617373964394e-26 2.8535991274741267e-25 1.2624618565484314e-25 8841/79718/79885/2648/9734/55869/23462/51564/55534/6500/84441/3091/10013/10046/7316/83933/9978/9611/9759/9612/1024/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/9794/6233/23493/7311/3516/4851/7314 38 Human_papillomavirus_type_18 R-HSA-202403 TCR signaling 63/1364 119/10654 4.631350656137775e-26 4.079530152427742e-25 1.804826459502739e-25 1147/5718/5689/8945/55740/5684/5290/5720/4790/5682/5700/122706/7321/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5970/4792/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/7408/5728/5699/5710/5702/5719/7189/5704/6233/5716/7311/7334/5694/3551/5693/5721/5696/5691/7314 63 Human_papillomavirus_type_18 R-HSA-201681 TCF dependent signaling in response to WNT 93/1364 233/10654 6.34148398912134e-26 5.546565573583594e-25 2.453858148496175e-25 5718/27123/9070/5689/8945/5684/8295/857/5720/7015/1487/6597/5682/1499/864/1459/5700/122706/5707/1856/207/8085/1454/1452/5690/5717/5929/9491/23198/1460/143471/5706/5705/10197/6657/7534/7316/10213/5709/9978/5695/1457/5714/4609/9861/5715/5519/5711/2932/5701/10524/5688/1387/5687/1455/5685/5683/5698/5708/5692/5686/5713/2033/54894/5699/8312/5710/5702/3065/5719/208/57680/5704/6233/5527/1855/5716/7514/23072/7311/5518/331/6659/5694/5693/5721/5696/6259/5691/7314/4221/5515/5516 93 Human_papillomavirus_type_18 R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 34/1364 39/10654 9.324398005862398e-26 8.088430206257587e-25 3.578405430686042e-25 6118/80010/83990/5888/9156/5883/1763/7486/10111/675/5982/545/472/580/11073/116028/641/6119/3364/10524/4683/144715/5985/84126/1111/5984/672/5932/7156/5983/6117/5884/5810/83695 34 Human_papillomavirus_type_18 R-HSA-5683057 MAPK family signaling cascades 107/1364 294/10654 9.377890094211695e-26 8.088430206257587e-25 3.578405430686042e-25 5718/5689/27161/3725/5684/4893/5720/2309/5682/1844/2904/5747/153090/5700/10642/3815/122706/5707/10048/5690/57690/5594/5717/9491/3315/23198/27327/5908/143471/5706/2064/5705/10197/3337/192670/8550/7316/10213/5709/9978/1950/5695/4233/983/5597/5714/6714/4609/9861/5715/5519/5711/5701/5688/5159/5687/3717/2247/5685/5683/5698/5708/5692/5686/5713/5699/5710/2264/816/8555/5702/192669/998/2066/8556/5719/23112/5704/6233/5527/5716/7514/7311/8826/5518/1956/60/4343/3845/5694/3265/26523/369/4763/8202/3569/5693/5721/5696/5691/5245/7529/5156/7314/5595/5515/5516 107 Human_papillomavirus_type_18 R-HSA-3858494 Beta-catenin independent WNT signaling 70/1364 146/10654 1.9654124600520703e-25 1.6834774312997735e-24 7.447878795986794e-25 57154/5718/5689/27161/5684/5720/5682/1499/51701/4772/5700/122706/5707/1856/5690/1212/57690/5717/9491/23198/27327/143471/5706/5705/10197/192670/5530/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5534/5699/2783/5710/5702/192669/5719/23112/5704/6233/1855/5716/7311/1213/1211/4343/3845/5694/26523/5693/5721/5696/6259/5691/7314 70 Human_papillomavirus_type_18 R-HSA-1236974 ER-Phagosome pathway 51/1364 83/10654 1.986237719097137e-25 1.6896624980264686e-24 7.475242172809701e-25 1147/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/29927/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/3551/5693/5721/5696/5691/7314 51 Human_papillomavirus_type_18 R-HSA-5693532 DNA Double-Strand Break Repair 75/1364 166/10654 4.0791703520514507e-25 3.446482705610817e-24 1.5247597019483404e-24 8467/1017/6118/80010/25/3838/83990/5888/9156/5883/1763/7486/10111/51588/7520/51720/675/7515/5982/63967/5531/51548/11200/545/472/6613/7336/580/11073/5591/7316/116028/890/641/5111/64421/9656/6119/3364/22976/7341/10524/4683/144715/5985/84126/142/1111/7157/8900/5984/7329/79728/8924/6233/2067/51426/672/5932/7158/7311/6047/79184/7156/5983/6117/5599/7334/5981/10714/2547/5884/5810/83695/7314 75 Human_papillomavirus_type_18 R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 35/1364 42/10654 4.220780382852376e-25 3.5420332672315205e-24 1.5670322616279805e-24 6118/80010/83990/5888/9156/5883/1763/7486/10111/675/5982/545/472/580/11073/116028/641/6119/3364/10524/4683/144715/5985/84126/1111/5984/79728/672/5932/7156/5983/6117/5884/5810/83695 35 Human_papillomavirus_type_18 R-HSA-167161 HIV Transcription Initiation 37/1364 47/10654 8.589939780048422e-25 6.927730653779313e-24 3.0648999078504965e-24 6884/6875/5434/5440/902/5430/6874/5436/6878/5441/5438/5431/5435/5433/6872/4331/8148/6879/54457/5437/83860/2965/2068/5439/2071/6873/2968/6881/51616/6880/6908/6883/6882/138474/1022/5432/6877 37 Human_papillomavirus_type_18 R-HSA-167162 RNA Polymerase II HIV Promoter Escape 37/1364 47/10654 8.589939780048422e-25 6.927730653779313e-24 3.0648999078504965e-24 6884/6875/5434/5440/902/5430/6874/5436/6878/5441/5438/5431/5435/5433/6872/4331/8148/6879/54457/5437/83860/2965/2068/5439/2071/6873/2968/6881/51616/6880/6908/6883/6882/138474/1022/5432/6877 37 Human_papillomavirus_type_18 R-HSA-73776 RNA Polymerase II Promoter Escape 37/1364 47/10654 8.589939780048422e-25 6.927730653779313e-24 3.0648999078504965e-24 6884/6875/5434/5440/902/5430/6874/5436/6878/5441/5438/5431/5435/5433/6872/4331/8148/6879/54457/5437/83860/2965/2068/5439/2071/6873/2968/6881/51616/6880/6908/6883/6882/138474/1022/5432/6877 37 Human_papillomavirus_type_18 R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 37/1364 47/10654 8.589939780048422e-25 6.927730653779313e-24 3.0648999078504965e-24 6884/6875/5434/5440/902/5430/6874/5436/6878/5441/5438/5431/5435/5433/6872/4331/8148/6879/54457/5437/83860/2965/2068/5439/2071/6873/2968/6881/51616/6880/6908/6883/6882/138474/1022/5432/6877 37 Human_papillomavirus_type_18 R-HSA-75953 RNA Polymerase II Transcription Initiation 37/1364 47/10654 8.589939780048422e-25 6.927730653779313e-24 3.0648999078504965e-24 6884/6875/5434/5440/902/5430/6874/5436/6878/5441/5438/5431/5435/5433/6872/4331/8148/6879/54457/5437/83860/2965/2068/5439/2071/6873/2968/6881/51616/6880/6908/6883/6882/138474/1022/5432/6877 37 Human_papillomavirus_type_18 R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 37/1364 47/10654 8.589939780048422e-25 6.927730653779313e-24 3.0648999078504965e-24 6884/6875/5434/5440/902/5430/6874/5436/6878/5441/5438/5431/5435/5433/6872/4331/8148/6879/54457/5437/83860/2965/2068/5439/2071/6873/2968/6881/51616/6880/6908/6883/6882/138474/1022/5432/6877 37 Human_papillomavirus_type_18 R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 49/1364 79/10654 9.589829235916613e-25 7.684237361940926e-24 3.3995863233605924e-24 9318/6118/5434/5440/902/2074/5430/5436/7515/5982/5441/5438/5431/8450/5435/7316/9978/5433/4331/5111/6119/5437/1161/1642/2965/5985/2033/2068/5439/10987/2071/5984/6233/2067/51426/2873/2968/7311/5983/6117/5981/10714/7874/1022/5432/8178/7314/51138/8451 49 Human_papillomavirus_type_18 R-HSA-69473 G2/M DNA damage checkpoint 54/1364 95/10654 1.6290104571169023e-24 1.2969429408584568e-23 5.7378101121121656e-24 6118/80010/83990/9156/5883/1763/7531/7486/10111/7532/10971/51588/51720/5982/7533/2810/11200/545/472/7336/7534/580/11073/891/116028/983/641/9656/6119/3364/7341/10524/4683/144715/5985/995/84126/1111/7157/5984/8924/672/5932/7158/79184/7156/5983/6117/7334/7465/5884/5810/83695/7529 54 Human_papillomavirus_type_18 R-HSA-68882 Mitotic Anaphase 83/1364 201/10654 2.0297246268804487e-24 1.6056802462328133e-23 7.103695978756918e-24 4000/5718/5689/11130/5684/5903/5720/5682/55869/1058/5700/122706/7321/5707/991/51807/5690/9212/5717/9491/23198/7277/143471/5706/5705/10197/6232/332/7443/5885/7316/10213/5709/5695/5501/5714/9861/3796/5715/5519/5711/5701/5688/699/5687/7846/5685/5683/7444/5698/5708/5692/5686/5713/8243/9126/5699/5710/5702/5719/9232/5704/6233/5527/5716/701/7514/7311/5518/10383/5347/84790/6396/5694/7112/5693/5721/5696/7280/5691/7314/5515/5516 83 Human_papillomavirus_type_18 R-HSA-2555396 Mitotic Metaphase and Anaphase 83/1364 202/10654 3.029464670448404e-24 2.3813893168967835e-23 1.0535513377575397e-23 4000/5718/5689/11130/5684/5903/5720/5682/55869/1058/5700/122706/7321/5707/991/51807/5690/9212/5717/9491/23198/7277/143471/5706/5705/10197/6232/332/7443/5885/7316/10213/5709/5695/5501/5714/9861/3796/5715/5519/5711/5701/5688/699/5687/7846/5685/5683/7444/5698/5708/5692/5686/5713/8243/9126/5699/5710/5702/5719/9232/5704/6233/5527/5716/701/7514/7311/5518/10383/5347/84790/6396/5694/7112/5693/5721/5696/7280/5691/7314/5515/5516 83 Human_papillomavirus_type_18 R-HSA-109606 Intrinsic Pathway for Apoptosis 39/1364 53/10654 3.704430806561844e-24 2.89364972437095e-23 1.2801806560908858e-23 23368/27113/596/10018/7531/1029/7027/842/7532/207/10971/5594/7533/2810/841/7534/1869/6774/54205/4836/5366/598/836/10000/708/5534/7157/8626/208/7161/331/581/5599/7159/637/317/7529/578/5595 39 Human_papillomavirus_type_18 R-HSA-195721 Signaling by WNT 112/1364 331/10654 7.426842078002812e-24 5.765086163049683e-23 2.550533924156229e-23 57154/5718/27123/9070/5689/27161/8945/5684/8295/857/5720/7015/1487/6597/5682/1499/51701/864/1459/4772/5700/122706/5707/1856/207/8085/1454/1452/5690/1212/57690/5717/5929/9491/23198/6500/27327/1460/143471/5706/5705/10197/6657/192670/7534/5530/7316/10213/5709/9978/5695/1457/5714/4609/9861/5715/5519/5711/2932/5701/10524/5688/1387/5687/1455/5685/5683/5698/5708/5692/5686/5713/2033/54894/5534/5699/2783/8312/5710/5702/192669/3065/5719/23112/208/57680/5704/6233/5527/1855/5716/7514/23072/7311/5518/1213/1211/331/4343/3845/6659/5694/26523/5693/5721/5696/6259/5691/7314/4221/5515/5516 112 Human_papillomavirus_type_18 R-HSA-8951664 Neddylation 90/1364 234/10654 9.287497114530643e-24 7.164640631209353e-23 3.16971133951291e-23 9318/5718/5689/8945/5684/5720/11091/23363/5682/23038/5700/122706/7321/5707/4738/5690/5717/5929/9491/23198/6500/5931/3091/143471/5706/5705/26259/10197/332/26263/8450/7316/10213/5709/9978/5695/5714/26272/7704/1643/26118/9861/5715/5711/5701/5688/5687/1161/6502/23291/5685/5683/55832/5698/5708/1642/5692/5686/23113/5713/55294/5699/10238/5710/10987/7428/5702/9040/5719/80176/5704/6233/2873/5716/7311/83987/80204/51667/5694/23014/5693/5721/5696/5691/9820/7314/51514/10537/51138/8451 90 Human_papillomavirus_type_18 R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 78/1364 185/10654 1.0557199047476801e-23 8.093852603065548e-23 3.580804355284529e-23 6158/6138/6144/2091/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/6230/6222/1454/6152/6136/27043/6125/6224/6154/51065/6141/6202/6232/6134/6160/55272/6164/6155/6175/6218/6209/6193/10200/6210/6231/6229/6205/6165/6130/6142/6204/6228/23521/23481/140801/6156/6143/6181/6124/6207/10969/6233/7311/6223/26168/11340/6188/6189/26354/6135/6201/6161/1453/9045/6187/4691/23016/6168/6208/54512/6137/10813/6122 78 Human_papillomavirus_type_18 R-HSA-5693607 Processing of DNA double-strand break ends 54/1364 98/10654 1.2681595068940619e-23 9.6629086353523e-23 4.27497102097966e-23 1017/6118/80010/83990/9156/5883/1763/7486/10111/51588/51720/5982/63967/5531/51548/545/472/6613/7336/580/11073/7316/116028/890/641/9656/6119/3364/7341/10524/4683/144715/5985/84126/1111/8900/5984/7329/8924/6233/672/5932/7158/7311/6047/79184/7156/5983/6117/7334/5884/5810/83695/7314 54 Human_papillomavirus_type_18 R-HSA-350054 Notch-HLH transcription pathway 27/1364 28/10654 1.5486964768340313e-23 1.1728542830657726e-22 5.1888290173771784e-23 8841/79718/79885/2648/9734/55869/51564/55534/84441/10013/10046/83933/4854/9611/9759/9612/10014/22938/8850/1387/6907/4855/3066/3065/9794/3516/4851 27 Human_papillomavirus_type_18 R-HSA-2467813 Separation of Sister Chromatids 79/1364 190/10654 1.5969859463207544e-23 1.1995275848291938e-022 5.306834471402994e-23 5718/5689/11130/5684/5903/5720/5682/55869/1058/5700/122706/7321/5707/991/51807/5690/9212/5717/9491/23198/7277/143471/5706/5705/10197/6232/332/5885/7316/10213/5709/5695/5501/5714/9861/3796/5715/5519/5711/5701/5688/699/5687/7846/5685/5683/5698/5708/5692/5686/5713/8243/9126/5699/5710/5702/5719/9232/5704/6233/5527/5716/701/7514/7311/5518/10383/5347/84790/6396/5694/5693/5721/5696/7280/5691/7314/5515/5516 79 Human_papillomavirus_type_18 R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 43/1364 65/10654 1.6032333259391804e-23 1.1995275848291938e-022 5.306834471402994e-23 6118/5434/5440/902/2074/5430/5436/7515/5982/5441/5438/5431/8450/5435/7316/9978/5433/4331/5111/6119/5437/1161/1642/2965/5985/2033/2068/5439/2071/5984/6233/51426/2968/7311/5983/6117/5981/10714/7874/1022/5432/7314/8451 43 Human_papillomavirus_type_18 R-HSA-8939211 ESR-mediated signaling 87/1364 223/10654 1.68554406210871e-23 1.2535603144545015e-22 5.545880872491313e-23 27161/3725/3838/596/5434/5440/5590/4893/857/5290/7764/5241/2309/5747/5430/207/5436/57690/5594/1027/3315/27327/4318/5441/5481/192670/5438/5431/5885/2100/5435/4313/5433/1950/5469/1655/6667/6714/2099/4609/7391/8850/10524/1387/5437/10000/3320/2033/8243/4846/9126/595/2783/4602/8312/5439/192669/3065/2066/23028/23112/208/10498/3326/7514/1385/1025/2353/10499/1386/6908/1956/3169/4343/3845/3276/3265/26523/8202/5432/8648/3480/2288/10728/5595/7528/6387 87 Human_papillomavirus_type_18 R-HSA-8868773 rRNA processing in the nucleus and cytosol 80/1364 195/10654 2.3558682911016758e-23 1.7416597723501675e-22 7.705283508490442e-23 6158/6138/6144/2091/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/55226/6230/6222/1454/6152/6136/27043/6125/4839/6224/6154/51065/6141/6202/6232/6134/6160/55272/6164/6155/6175/6218/6209/6193/10200/6210/6231/6229/6205/6165/6130/6142/6204/6228/23521/23481/140801/6156/6143/6181/6124/6207/10969/6233/7311/6223/26168/11340/6188/6189/26354/6135/6201/6161/1453/9045/6187/4691/23016/6168/6208/54512/6137/10813/6122 80 Human_papillomavirus_type_18 R-HSA-162587 HIV Life Cycle 69/1364 152/10654 2.4172815826853497e-23 1.776487411653967e-22 7.859364597706339e-23 6884/6875/5434/5440/5903/7852/902/7175/9631/3159/5430/6874/5436/7520/6878/6749/5441/23636/5438/5431/5435/7316/5433/6872/4331/4836/9397/4927/9688/8148/6879/54457/5437/8812/83860/23225/2965/128866/2068/5439/2071/5901/6873/6233/2968/7514/1025/7311/9972/6881/51616/6880/6908/8021/7251/11198/6396/6883/1104/51497/2547/6882/138474/1022/5432/8178/8480/6877/7314 69 Human_papillomavirus_type_18 R-HSA-3899300 SUMOylation of transcription cofactors 35/1364 45/10654 3.382082438516836e-23 2.470909640375241e-22 1.093156057526804e-22 1912/1487/3622/8535/6045/51588/4869/80012/6613/10210/28996/1655/9612/1911/7341/1387/84733/10521/1616/2033/57332/7329/115426/10155/10499/6612/9063/25942/6294/648/11315/8648/10891/6015/8554 35 Human_papillomavirus_type_18 R-HSA-5358351 Signaling by Hedgehog 68/1364 149/10654 3.470750441028907e-23 2.5208608466420485e-22 1.1152549893610893e-22 57154/5718/5689/8945/5684/5720/2735/5682/5700/122706/5707/22873/1452/5690/5717/9491/23198/6500/7277/143471/5706/5705/10197/84447/7316/10213/5709/9978/5695/8650/5714/7415/9861/5715/5711/2932/5701/5688/5687/7846/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/83737/5719/5704/6233/5716/7311/10383/6469/23322/84790/5694/8481/5693/5721/5696/7280/5691/7314 68 Human_papillomavirus_type_18 R-HSA-5693538 Homology Directed Repair 65/1364 138/10654 3.7040803989257577e-23 2.674690613642902e-22 1.1833108740754256e-22 1017/6118/80010/25/83990/5888/9156/5883/1763/7486/10111/51588/51720/675/7515/5982/63967/5531/51548/545/472/6613/7336/580/11073/7316/116028/890/641/5111/9656/6119/3364/7341/10524/4683/144715/5985/84126/142/1111/8900/5984/7329/79728/8924/6233/2067/51426/672/5932/7158/7311/6047/79184/7156/5983/6117/7334/5981/10714/5884/5810/83695/7314 65 Human_papillomavirus_type_18 R-HSA-6782135 Dual incision in TC-NER 43/1364 66/10654 4.040668601403588e-23 2.900873065285119e-22 1.2833763370445226e-22 6118/5434/5440/902/2074/5430/5436/5982/5441/5438/5431/8450/5435/7316/9978/5433/4331/5111/6119/5437/1161/1642/2965/5985/2033/2068/5439/2071/5984/6233/2067/51426/2968/7311/5983/6117/5981/10714/7874/1022/5432/7314/8451 43 Human_papillomavirus_type_18 R-HSA-162599 Late Phase of HIV Life Cycle 65/1364 139/10654 6.113642011390053e-23 4.363875504681866e-22 1.9306237930705435e-22 6884/6875/5434/5440/5903/902/7175/9631/5430/6874/5436/6878/6749/5441/23636/5438/5431/5435/7316/5433/6872/4331/4836/9397/4927/9688/8148/6879/54457/5437/8812/83860/23225/2965/128866/2068/5439/2071/5901/6873/6233/2968/7514/1025/7311/9972/6881/51616/6880/6908/8021/7251/11198/6396/6883/1104/51497/6882/138474/1022/5432/8178/8480/6877/7314 65 Human_papillomavirus_type_18 R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 63/1364 132/10654 7.18372243955588e-23 5.098390439959088e-22 2.2555808201191997e-22 1017/6118/80010/25/83990/5888/9156/5883/1763/7486/10111/51588/51720/675/5982/63967/5531/51548/545/472/6613/7336/580/11073/7316/116028/890/641/5111/9656/6119/3364/7341/10524/4683/144715/5985/84126/1111/8900/5984/7329/79728/8924/6233/2067/51426/672/5932/7158/7311/6047/79184/7156/5983/6117/7334/5981/10714/5884/5810/83695/7314 63 Human_papillomavirus_type_18 R-HSA-5685942 HDR through Homologous Recombination (HRR) 43/1364 67/10654 9.907329908426226e-23 6.9914225831053255e-22 3.0930778781091447e-22 6118/80010/83990/5888/9156/5883/1763/7486/10111/675/5982/545/472/580/11073/7316/116028/641/5111/6119/3364/10524/4683/144715/5985/84126/1111/5984/79728/6233/51426/672/5932/7311/7156/5983/6117/5981/10714/5884/5810/83695/7314 43 Human_papillomavirus_type_18 R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 54/1364 102/10654 1.6491502353769595e-22 1.1572003346543411e-21 5.119574325701891e-22 7124/1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 54 Human_papillomavirus_type_18 R-HSA-72312 rRNA processing 81/1364 205/10654 2.2747750127262107e-22 1.587230654947165e-21 7.022073072992796e-22 6158/6138/6144/2091/6203/9349/4736/6194/6191/6128/51121/6132/6147/6129/6217/55226/6230/6222/1454/6152/6136/27043/6125/4839/6224/6154/51065/6141/6202/6232/6134/6160/55272/6164/6155/6175/6218/54931/6209/6193/10200/6210/6231/6229/6205/6165/6130/6142/6204/6228/23521/23481/140801/6156/6143/6181/6124/6207/10969/6233/7311/6223/26168/11340/6188/6189/26354/6135/6201/6161/1453/9045/6187/4691/23016/6168/6208/54512/6137/10813/6122 81 Human_papillomavirus_type_18 R-HSA-9006931 Signaling by Nuclear Receptors 101/1364 299/10654 1.5705044477403394e-21 1.0849541691293779e-20 4.7999497947752795e-21 27161/3725/3838/596/5434/5440/5590/4893/8841/857/112724/5290/7764/79718/5241/2309/5747/5160/5430/207/5436/10901/57690/5594/1027/3315/27327/5915/4318/5441/5481/6720/192670/5438/5431/5885/2100/5435/4313/5433/1950/9611/5469/2874/1655/9612/6667/6714/2099/4609/7391/8850/10524/1387/5437/6907/10000/3320/2033/8243/4846/9126/595/2783/4602/8312/5439/192669/3065/2066/23028/6256/23112/208/10498/3326/7514/1385/1025/2353/10499/1386/6908/1956/5914/3169/4343/3845/1071/3276/3265/26523/8202/5432/8648/3480/2288/10728/5595/7528/6387 101 Human_papillomavirus_type_18 R-HSA-3371556 Cellular response to heat stress 49/1364 89/10654 1.5723973465643156e-21 1.0849541691293779e-20 4.7999497947752795e-21 3303/6118/5903/573/7175/9631/7531/1915/5594/3308/10049/1410/10013/545/472/23636/3337/3313/3305/9532/4927/9688/7415/6119/2932/1387/57805/23225/3310/3309/3320/2033/7266/816/3326/2475/3306/9972/23411/8021/9529/6117/6396/3304/3312/2288/8480/10728/5595 49 Human_papillomavirus_type_18 R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 36/1364 51/10654 2.211184141080368e-21 1.5172876813380203e-20 6.7126381020293804e-21 6203/6194/6191/8666/6217/6230/6222/8668/8667/6224/51065/8662/10480/6202/6232/6218/6209/6193/6210/6231/6229/6205/6204/6228/8894/6207/6233/6223/3646/51386/6188/6189/8665/6201/6187/6208 36 Human_papillomavirus_type_18 R-HSA-72766 Translation 99/1364 291/10654 2.2238469187371014e-21 1.5175922379513626e-20 6.7139854920807805e-21 6158/6138/6144/5464/6203/9349/4736/6194/6191/6128/51121/6132/1938/6147/56945/8666/6129/1915/6217/6230/6222/6152/6136/79590/8668/64432/8667/6125/6224/6154/51065/8662/6141/10480/6184/26986/6202/6232/6134/6160/6164/6155/63931/6175/6218/29927/9669/6209/6193/6210/6231/6229/6205/6165/6130/6142/6204/64969/6228/23521/54148/23107/8894/7965/140801/6156/6143/1973/6181/6124/6185/28973/6207/64978/51116/6233/28957/64975/7311/6223/3646/51386/6188/6189/8665/6135/6201/6161/9045/51649/6187/54998/64965/6168/6208/6137/7284/6122/55037 99 Human_papillomavirus_type_18 R-HSA-71291 Metabolism of amino acids and derivatives 116/1364 372/10654 2.4872022031594426e-21 1.6880355936196872e-20 7.468044578942934e-21 6158/5718/5689/6138/6144/6203/5684/27165/9349/4736/1728/5720/6194/6191/6128/5682/51121/6132/6147/6129/5160/6217/5700/122706/5707/6230/6222/1743/6152/5690/6136/6125/5717/9491/23198/6224/6154/51065/6141/143471/6202/5706/5705/10197/6232/6134/6160/6164/6155/10213/5709/6175/6218/5695/6209/5714/6193/6210/6231/6229/6205/6165/9861/6130/5715/6142/5711/6204/5701/5688/6228/23521/5687/5832/23474/5685/5683/5698/5708/7965/5692/5686/5713/140801/6156/5699/6143/5710/6181/6124/5702/6207/5719/5704/6233/5716/7311/6223/6188/6189/6135/6201/6161/6303/5694/9045/6187/6168/5693/6208/5721/6137/5696/5691/6122/7296 116 Human_papillomavirus_type_18 R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 41/1364 65/10654 2.6044390619609234e-21 1.7579963668236232e-20 7.777558297160194e-21 2176/3725/5434/5440/4436/8621/902/5430/5436/6749/4292/545/472/5441/5438/5431/5435/5433/4331/1643/5395/9656/5437/8812/2965/51755/2068/5439/1111/2071/7157/2968/672/1025/2353/1386/11198/51497/1022/5432/8178 41 Human_papillomavirus_type_18 R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 47/1364 84/10654 4.2078258372716636e-021 2.8249295621034626e-20 1.249778143417245e-20 9318/6118/902/7515/5982/9557/6613/7336/86/8450/7316/9978/4331/5111/1643/6119/7341/1642/2965/5985/142/2068/10987/2071/5984/7329/6233/2067/51426/2873/2968/7311/6612/60/5983/6117/7334/5981/10714/1022/5886/7508/7314/51138/8451/8554/7528 47 Human_papillomavirus_type_18 R-HSA-6806003 Regulation of TP53 Expression and Degradation 30/1364 37/10654 5.2017021613709245e-21 3.473394669044456e-20 1.5366658337496452e-20 1017/1029/207/11200/472/117584/639/7316/890/80196/983/4194/5519/1616/10000/900/7157/8900/208/6233/5527/2475/7311/5518/7874/51230/7314/4193/5515/5516 30 Human_papillomavirus_type_18 R-HSA-68886 M Phase 120/1364 395/10654 5.549684846714577e-21 3.685940416908826e-20 1.6306982775035233e-20 10844/4000/115106/5718/5689/11130/22995/5684/5903/5720/7175/5682/22981/9631/7531/1459/55869/1058/5700/122706/7321/5707/991/203068/51807/7532/1454/5690/9212/5594/5717/9491/23198/5925/1460/7277/143471/5706/5705/23636/25836/10197/6232/332/7443/5885/7316/10213/5709/891/5695/5501/1457/983/5714/4927/9688/9861/3796/8615/5715/5519/5711/5701/5688/699/5687/7846/23225/5685/7283/5683/7444/5698/5708/3320/5692/5686/5713/80097/8243/9126/5699/5710/5702/10540/5719/9232/5704/6233/5527/5716/701/7514/7311/54930/9972/5518/10383/55835/5347/84790/8021/6396/9662/5694/1453/6418/8481/7112/5693/5721/5696/7280/5691/8480/7314/5595/5515/5516 120 Human_papillomavirus_type_18 R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 38/1364 58/10654 1.0462504414346182e-20 6.732865535035211e-20 2.978689557834037e-20 8841/79718/79885/2648/9734/55869/23462/51564/55534/6500/84441/10013/10046/7316/83933/9978/9611/9759/9612/1024/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/9794/6233/23493/7311/3516/4851/5663/7314 38 Human_papillomavirus_type_18 R-HSA-2644603 Signaling by NOTCH1 in Cancer 38/1364 58/10654 1.0462504414346182e-20 6.732865535035211e-20 2.978689557834037e-20 8841/79718/79885/2648/9734/55869/23462/51564/55534/6500/84441/10013/10046/7316/83933/9978/9611/9759/9612/1024/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/9794/6233/23493/7311/3516/4851/5663/7314 38 Human_papillomavirus_type_18 R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 38/1364 58/10654 1.0462504414346182e-20 6.732865535035211e-20 2.978689557834037e-20 8841/79718/79885/2648/9734/55869/23462/51564/55534/6500/84441/10013/10046/7316/83933/9978/9611/9759/9612/1024/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/9794/6233/23493/7311/3516/4851/5663/7314 38 Human_papillomavirus_type_18 R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 38/1364 58/10654 1.0462504414346182e-20 6.732865535035211e-20 2.978689557834037e-20 8841/79718/79885/2648/9734/55869/23462/51564/55534/6500/84441/10013/10046/7316/83933/9978/9611/9759/9612/1024/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/9794/6233/23493/7311/3516/4851/5663/7314 38 Human_papillomavirus_type_18 R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 38/1364 58/10654 1.0462504414346182e-20 6.732865535035211e-20 2.978689557834037e-20 8841/79718/79885/2648/9734/55869/23462/51564/55534/6500/84441/10013/10046/7316/83933/9978/9611/9759/9612/1024/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/9794/6233/23493/7311/3516/4851/5663/7314 38 Human_papillomavirus_type_18 R-HSA-72649 Translation initiation complex formation 38/1364 58/10654 1.0462504414346182e-20 6.732865535035211e-20 2.978689557834037e-20 6203/6194/6191/8666/6217/6230/6222/8668/8667/6224/51065/8662/10480/26986/6202/6232/6218/6209/6193/6210/6231/6229/6205/6204/6228/8894/1973/6207/6233/6223/3646/51386/6188/6189/8665/6201/6187/6208 38 Human_papillomavirus_type_18 R-HSA-1236975 Antigen processing-Cross presentation 51/1364 99/10654 1.2505639954008383e-20 8.00618805303011e-20 3.5420206489378056e-20 1147/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/29927/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/3551/5693/5721/5696/5691/7314 51 Human_papillomavirus_type_18 R-HSA-167172 Transcription of the HIV genome 43/1364 73/10654 1.303769547420168e-20 8.304009117414608e-20 3.6737797773458985e-20 6884/6875/5434/5440/902/5430/6874/5436/6878/6749/5441/5438/5431/5435/5433/6872/4331/8148/6879/54457/5437/8812/83860/2965/2068/5439/2071/6873/2968/1025/6881/51616/6880/6908/11198/6883/51497/6882/138474/1022/5432/8178/6877 43 Human_papillomavirus_type_18 R-HSA-382556 ABC-family proteins mediated transport 52/1364 103/10654 1.716721307390268e-20 1.087840746825874e-19 4.812720313951235e-20 5718/5689/5684/5720/5682/5700/122706/5707/5243/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/8894/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 52 Human_papillomavirus_type_18 R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 38/1364 59/10654 2.581766776300776e-20 1.62769255642922e-19 7.201080722570158e-20 6203/6194/6191/8666/6217/6230/6222/8668/8667/6224/51065/8662/10480/26986/6202/6232/6218/6209/6193/6210/6231/6229/6205/6204/6228/8894/1973/6207/6233/6223/3646/51386/6188/6189/8665/6201/6187/6208 38 Human_papillomavirus_type_18 R-HSA-6804757 Regulation of TP53 Degradation 29/1364 36/10654 3.3582822493942136e-20 2.1065588655290976e-19 9.319634950471981e-20 1017/1029/207/11200/472/117584/7316/890/80196/983/4194/5519/1616/10000/900/7157/8900/208/6233/5527/2475/7311/5518/7874/51230/7314/4193/5515/5516 29 Human_papillomavirus_type_18 R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 46/1364 85/10654 7.036782035315988e-20 4.348101138240028e-19 1.923645049717175e-19 1147/3725/8945/5601/351/4790/5606/5594/4214/6500/7316/5970/4792/4205/4793/3146/5519/5598/1432/4208/23291/5602/6195/57162/10454/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 46 Human_papillomavirus_type_18 R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 46/1364 85/10654 7.036782035315988e-20 4.348101138240028e-19 1.923645049717175e-19 1147/3725/8945/5601/351/4790/5606/5594/4214/6500/7316/5970/4792/4205/4793/3146/5519/5598/1432/4208/23291/5602/6195/57162/10454/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 46 Human_papillomavirus_type_18 R-HSA-975871 MyD88 cascade initiated on plasma membrane 46/1364 85/10654 7.036782035315988e-20 4.348101138240028e-19 1.923645049717175e-19 1147/3725/8945/5601/351/4790/5606/5594/4214/6500/7316/5970/4792/4205/4793/3146/5519/5598/1432/4208/23291/5602/6195/57162/10454/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 46 Human_papillomavirus_type_18 R-HSA-69231 Cyclin D associated events in G1 32/1364 44/10654 8.775923730549897e-20 5.369309001646784e-19 2.3754380022541077e-19 25/1019/902/1029/7027/1027/6500/5925/5934/7316/1869/4331/1026/5933/6714/1031/5519/4067/3717/6502/1021/1874/595/6233/1030/7311/5518/1022/1028/7314/5515/5516 32 Human_papillomavirus_type_18 R-HSA-69236 G1 Phase 32/1364 44/10654 8.775923730549897e-20 5.369309001646784e-19 2.3754380022541077e-19 25/1019/902/1029/7027/1027/6500/5925/5934/7316/1869/4331/1026/5933/6714/1031/5519/4067/3717/6502/1021/1874/595/6233/1030/7311/5518/1022/1028/7314/5515/5516 32 Human_papillomavirus_type_18 R-HSA-72702 Ribosomal scanning and start codon recognition 37/1364 58/10654 1.3307238447645605e-19 8.1017598784195295e-19 3.584302615929311e-19 6203/6194/6191/8666/6217/6230/6222/8668/8667/6224/51065/8662/10480/6202/6232/6218/6209/6193/6210/6231/6229/6205/6204/6228/8894/1973/6207/6233/6223/3646/51386/6188/6189/8665/6201/6187/6208 37 Human_papillomavirus_type_18 R-HSA-73762 RNA Polymerase I Transcription Initiation 33/1364 47/10654 1.3748614691890949e-19 8.3296485108919795e-019 3.685122910997215e-19 5434/5440/902/9015/2648/2074/9112/9219/9014/5931/5441/51082/5435/4331/9013/1108/8850/5928/5437/57459/2965/54815/2068/3066/3065/2071/1107/2968/57504/6908/53615/1022/10919 33 Human_papillomavirus_type_18 R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 43/1364 77/10654 2.263805136538589e-19 1.3648766891169552e-18 6.038356061692097e-19 1912/5903/7175/9631/1029/7486/8535/51564/6045/51588/80012/6613/23636/5885/6996/1911/641/6672/4927/9688/9656/7341/84733/23225/8243/9126/57332/142/7329/5371/8924/672/9972/6612/9063/8021/6117/6396/648/8480/7508/6015/8554 43 Human_papillomavirus_type_18 R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 99/1364 309/10654 2.9470850021355795e-19 1.7682510012813475e-18 7.822925863792384e-19 57154/5718/23352/5689/8945/5684/5720/5682/7319/5700/122706/7321/5707/991/10273/7320/5690/5717/9491/23198/6500/10533/143471/5706/5705/26259/10197/7336/26263/7316/10213/5709/9978/5695/80196/7337/5714/26272/7704/8651/3093/26118/9861/25831/5715/5711/5701/5688/5687/6502/23291/5685/10616/5683/5698/5708/5692/5686/5713/25898/55294/5699/79654/5710/7428/5702/22954/83737/9040/5719/10075/80176/8924/51191/5704/6233/56658/5716/10425/51343/7311/6047/868/80204/57520/7334/5930/5694/23014/7332/5693/5721/5696/23608/55585/5691/9820/7314/140691 99 Human_papillomavirus_type_18 R-HSA-674695 RNA Polymerase II Pre-transcription Events 45/1364 84/10654 3.060794669020767e-19 1.827647586021054e-18 8.085702516340285e-19 6884/6875/5434/5440/902/6830/5430/6874/5436/6878/6749/5441/5438/5431/5435/5433/6872/4331/8148/6879/54457/5437/8812/83860/2965/2068/5439/2071/6873/2968/1025/6881/51616/6880/6908/11198/6883/51497/6882/138474/1022/5432/8178/55840/6877 45 Human_papillomavirus_type_18 R-HSA-2559585 Oncogene Induced Senescence 27/1364 33/10654 3.209340246982513e-19 1.907177314235541e-18 8.437550284184698e-19 1019/1029/7027/57690/5594/27327/5925/192670/7316/2114/1869/6667/4194/1031/1021/192669/7157/23112/6233/1030/7311/4343/26523/2113/7314/5595/4193 27 Human_papillomavirus_type_18 R-HSA-5696395 Formation of Incision Complex in GG-NER 31/1364 43/10654 5.089463774580972e-19 3.010054289537889e-18 1.331679243273818e-18 6118/902/9557/6613/7336/8450/7316/9978/4331/1643/6119/7341/1642/2965/142/2068/2071/7329/6233/2067/2968/7311/6612/6117/7334/1022/5886/7508/7314/8451/8554 31 Human_papillomavirus_type_18 R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 35/1364 54/10654 6.059138676977384e-19 3.5665640932729434e-18 1.57788495354562e-18 9318/5434/5440/902/2074/5430/5436/5441/5438/5431/8450/5435/7316/9978/5433/4331/5437/1161/1642/2965/2033/2068/5439/10987/2071/6233/2873/2968/7311/7874/1022/5432/7314/51138/8451 35 Human_papillomavirus_type_18 R-HSA-5628897 TP53 Regulates Metabolic Genes 45/1364 86/10654 1.0524006130976691e-18 6.165479063525024e-18 2.7276718969065705e-18 27161/5563/27165/83667/7531/7532/207/10971/9997/57690/51422/7249/27327/7295/7533/2810/53632/27244/192670/7534/2539/54205/143686/5571/10000/2877/10128/5728/54541/192669/7157/8626/23112/208/10542/2475/5562/4343/50484/26523/5564/5052/5565/7529/7296 45 Human_papillomavirus_type_18 R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 47/1364 93/10654 1.1425791662434573e-18 6.6312304881980095e-18 2.933725158775626e-18 1147/3665/3725/8945/5601/351/4790/5606/5594/4214/6500/7316/5970/4792/4205/4793/3146/5519/5598/1432/4208/23291/5602/6195/57162/10454/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 47 Human_papillomavirus_type_18 R-HSA-975155 MyD88 dependent cascade initiated on endosome 47/1364 93/10654 1.1425791662434573e-18 6.6312304881980095e-18 2.933725158775626e-18 1147/3665/3725/8945/5601/351/4790/5606/5594/4214/6500/7316/5970/4792/4205/4793/3146/5519/5598/1432/4208/23291/5602/6195/57162/10454/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 47 Human_papillomavirus_type_18 R-HSA-1980143 Signaling by NOTCH1 41/1364 73/10654 1.1785331170957546e-18 6.808084332246173e-18 3.0119671340219536e-18 8841/79718/79885/2648/9734/55869/23462/51564/55534/6500/84441/3091/10013/10046/7316/83933/9978/9611/8650/9759/9612/1024/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/83737/9794/6233/23493/7311/3516/4851/5663/7314 41 Human_papillomavirus_type_18 R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 48/1364 97/10654 1.507972816619235e-18 8.670843695560601e-18 3.8360712001717386e-018 1147/3665/3725/8945/5601/351/4790/5606/5594/4214/6500/8411/7316/5970/4792/4205/4793/3146/5519/5598/1432/4208/23291/5602/6195/57162/10454/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 48 Human_papillomavirus_type_18 R-HSA-5684996 MAPK1/MAPK3 signaling 86/1364 255/10654 1.9705463348816678e-18 1.1278426488124568e-17 4.9896928780413815e-18 5718/5689/5684/4893/5720/5682/1844/2904/5747/153090/5700/3815/122706/5707/10048/5690/5594/5717/9491/23198/5908/143471/5706/2064/5705/10197/7316/10213/5709/9978/1950/5695/4233/983/5714/6714/9861/5715/5519/5711/5701/5688/5159/5687/3717/2247/5685/5683/5698/5708/5692/5686/5713/5699/5710/2264/816/5702/2066/5719/5704/6233/5527/5716/7311/8826/5518/1956/60/3845/5694/3265/369/4763/3569/5693/5721/5696/5691/5245/7529/5156/7314/5595/5515/5516 86 Human_papillomavirus_type_18 R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 47/1364 94/10654 2.0070402845824266e-18 1.1434605658033826e-17 5.058788162974537e-18 1147/3665/3725/8945/5601/351/4790/5606/7321/5594/6500/841/7098/7316/5970/4792/4205/4793/3146/5519/5598/1432/4208/23291/5602/6195/10454/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595/5515/5516 47 Human_papillomavirus_type_18 R-HSA-6804758 Regulation of TP53 Activity through Acetylation 25/1364 30/10654 2.9662495439486476e-18 1.682229193417452e-17 7.442356462106196e-18 23774/64769/7862/3622/9219/207/5931/84289/1108/29117/5928/27154/57459/10000/54815/2033/7994/3066/3065/7157/1107/5371/208/5300/53615 25 Human_papillomavirus_type_18 R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 47/1364 95/10654 3.4888113684284296e-18 1.9606804161032168e-17 8.674253557130937e-18 1147/3725/8945/5601/351/4790/5606/5594/4214/6500/7316/5970/4792/4205/4793/8651/3146/5519/5598/1432/4208/23291/5602/6195/57162/10454/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 47 Human_papillomavirus_type_18 R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 47/1364 95/10654 3.4888113684284296e-18 1.9606804161032168e-17 8.674253557130937e-18 1147/3725/8945/5601/351/4790/5606/5594/4214/6500/7316/5970/4792/4205/4793/8651/3146/5519/5598/1432/4208/23291/5602/6195/57162/10454/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 47 Human_papillomavirus_type_18 R-HSA-9607240 FLT3 Signaling 88/1364 267/10654 4.148779485927998e-18 2.3210739286137717e-17 1.0268671842837434e-17 5718/5689/5684/4893/5290/5720/5682/1844/2904/5747/153090/5700/3815/122706/5707/10048/5690/5594/5717/9491/23198/5908/143471/5706/2064/5705/10197/6776/7316/10213/5709/9978/1950/5695/4233/5714/6714/9861/5715/5519/5711/5701/5688/5159/5687/3717/2247/5685/5683/5698/5708/5692/5686/5713/5699/5710/2264/816/5702/2066/5719/208/5704/6233/5527/5716/7311/8826/5518/1956/60/3845/6777/5694/3265/369/4763/5693/5721/5696/5691/5245/7529/5156/7314/5595/5515/5516 88 Human_papillomavirus_type_18 R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 46/1364 92/10654 4.643239762508254e-18 2.5860555089844177e-17 1.1440977842951658e-17 1147/3725/8945/5601/351/4790/5606/5594/4214/6500/7316/5970/4792/4205/4793/3146/5519/5598/1432/4208/23291/5602/6195/57162/10454/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 46 Human_papillomavirus_type_18 R-HSA-5673001 RAF/MAP kinase cascade 84/1364 249/10654 4.8883358229307934e-18 2.7104076303928773e-17 1.199112452805392e-17 5718/5689/5684/4893/5720/5682/1844/2904/5747/153090/5700/3815/122706/5707/10048/5690/5594/5717/9491/23198/5908/143471/5706/2064/5705/10197/7316/10213/5709/9978/1950/5695/4233/5714/6714/9861/5715/5519/5711/5701/5688/5159/5687/3717/2247/5685/5683/5698/5708/5692/5686/5713/5699/5710/2264/816/5702/2066/5719/5704/6233/5527/5716/7311/8826/5518/1956/60/3845/5694/3265/369/4763/5693/5721/5696/5691/5245/7529/5156/7314/5595/5515/5516 84 Human_papillomavirus_type_18 R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs 56/1364 130/10654 7.122310610614785e-18 3.9315154570593606e-17 1.7393432228027682e-17 5718/5689/25/5684/5720/902/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/4331/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/4602/5710/5702/83737/5719/5704/6233/5716/7311/7161/5694/1022/5693/5721/4297/5696/5691/7314 56 Human_papillomavirus_type_18 R-HSA-450294 MAP kinase activation 37/1364 64/10654 1.5476193524385937e-17 8.505058565171386e-17 3.762726138672315e-17 1147/3725/8945/5601/4790/5606/5594/6500/7316/4205/5519/5598/1432/4208/23291/5602/6195/10454/7189/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595/5515/5516 37 Human_papillomavirus_type_18 R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 47/1364 98/10654 1.7263271708141856e-17 9.403940114698328e-17 4.160400660964935e-17 1147/3725/8945/5601/351/4790/5606/5594/4214/6500/7316/5970/4792/4205/4793/8651/3146/5519/5598/1432/4208/23291/5602/6195/57162/10454/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 47 Human_papillomavirus_type_18 R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 47/1364 98/10654 1.7263271708141856e-17 9.403940114698328e-17 4.160400660964935e-17 1147/3725/8945/5601/351/4790/5606/5594/4214/6500/7316/5970/4792/4205/4793/8651/3146/5519/5598/1432/4208/23291/5602/6195/57162/10454/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 47 Human_papillomavirus_type_18 R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 20/1364 21/10654 2.2883235543985204e-17 1.2410907661846998e-16 5.490714297384636e-17 7832/4849/4869/4850/9337/10769/25904/246175/4848/23019/28984/995/7157/55571/55835/5325/57472/85456/29883/1263 20 Human_papillomavirus_type_18 R-HSA-9018519 Estrogen-dependent gene expression 60/1364 150/10654 3.5246265246265445e-17 1.9032983232983342e-16 8.420389225881265e-17 27161/3725/3838/596/5434/5440/7764/5241/5430/5436/57690/27327/5441/192670/5438/5431/5885/5435/5433/5469/1655/6667/2099/4609/7391/8850/10524/1387/5437/3320/2033/8243/9126/595/4602/8312/5439/192669/3065/2066/23028/23112/10498/3326/1025/2353/10499/1386/6908/3169/4343/3276/26523/8202/5432/8648/2288/10728/7528/6387 60 Human_papillomavirus_type_18 R-HSA-114452 Activation of BH3-only proteins 24/1364 30/10654 8.624623150702925e-17 4.63713504466365e-16 2.0515166482875036e-16 23368/27113/596/10018/7531/7027/7532/207/10971/7533/2810/7534/1869/5366/10000/5534/7157/8626/208/7161/5599/7159/637/7529 24 Human_papillomavirus_type_18 R-HSA-983169 Class I MHC mediated antigen processing & presentation 106/1364 371/10654 1.606941628427681e-16 8.602678890117155e-16 3.805914383118192e-16 57154/1147/5718/23352/5689/8945/5684/5720/5682/7319/5700/122706/7321/5707/991/10273/7320/5690/5717/9491/23198/6500/10533/143471/5706/5705/26259/10197/7336/26263/7316/10213/5709/9978/5695/29927/80196/22872/7337/5714/26272/7704/8651/3093/26118/9861/25831/5715/5711/5701/5688/5687/6502/23291/5685/10616/5683/3309/5698/5708/5692/5686/5713/25898/55294/5699/79654/5710/7428/5702/22954/83737/9040/5719/10075/80176/8924/51191/5704/6233/56658/5716/10425/51343/7311/9871/6047/868/80204/57520/6396/7334/5930/5694/3551/23014/7332/5693/5721/5696/23608/55585/5691/9820/7314/140691 106 Human_papillomavirus_type_18 R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 19/1364 20/10654 1.7236670146276395e-16 9.187958936341323e-16 4.0648483471227824e-16 23368/27113/55240/472/5366/84883/147923/1387/51499/94241/7157/8626/63970/7161/581/7159/637/665/27166 19 Human_papillomavirus_type_18 R-HSA-166166 MyD88-independent TLR4 cascade 46/1364 99/10654 1.8077882404321535e-16 9.55435316858185e-16 4.2269449563520007e-16 1147/3665/3725/8945/5601/351/4790/5606/7321/5594/6500/841/7316/5970/4792/4205/4793/3146/5519/5598/1432/4208/23291/5602/6195/10454/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595/5515/5516 46 Human_papillomavirus_type_18 R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 46/1364 99/10654 1.8077882404321535e-16 9.55435316858185e-16 4.2269449563520007e-16 1147/3665/3725/8945/5601/351/4790/5606/7321/5594/6500/841/7316/5970/4792/4205/4793/3146/5519/5598/1432/4208/23291/5602/6195/10454/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595/5515/5516 46 Human_papillomavirus_type_18 R-HSA-3371453 Regulation of HSF1-mediated heat shock response 37/1364 69/10654 4.515586083008442e-16 2.3764228453798665e-15 1.0513541192374696e-15 3303/6118/5903/573/7175/9631/7531/5594/3308/10049/545/472/23636/3337/3313/3305/9532/4927/9688/6119/2932/57805/23225/3310/3309/7266/3306/9972/23411/8021/9529/6117/6396/3304/3312/8480/5595 37 Human_papillomavirus_type_18 R-HSA-5619115 Disorders of transmembrane transporters 64/1364 176/10654 8.109957712708442e-16 4.250028472229488e-15 1.880256684891764e-15 5718/5689/5684/5903/5720/7175/5682/9631/5700/122706/5707/5690/285195/5717/9491/23198/1080/143471/5706/5705/23636/10197/7316/10213/5709/5695/5714/4927/9688/7415/9861/5715/5711/5701/5688/5687/23225/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/6514/5719/5704/6233/5716/7311/9972/8021/6396/5694/5693/5721/5696/5691/8480/6513/7314 64 Human_papillomavirus_type_18 R-HSA-6804760 Regulation of TP53 Activity through Methylation 18/1364 19/10654 1.2943034159882415e-15 6.754306061585697e-15 2.9881750691988594e-15 133383/11200/472/79813/7316/4194/56950/2033/7157/91875/6233/7311/10419/133746/26013/10919/7314/4193 18 Human_papillomavirus_type_18 R-HSA-212165 Epigenetic regulation of gene expression 57/1364 149/10654 2.3472277682408225e-15 1.2197727565502516e-14 5.396401211282579e-15 8467/23451/5252/5434/5440/902/9015/10514/2648/2074/2146/29128/1788/9112/9219/1786/6839/9014/5931/5441/51082/5435/8819/6996/4331/9013/23309/4641/1108/64426/79685/8850/5928/2932/29947/5437/57459/2965/54815/2033/23512/2068/3066/3065/2071/1107/2968/57504/6908/23411/60/25942/8726/10284/53615/1022/10919 57 Human_papillomavirus_type_18 R-HSA-448424 Interleukin-17 signaling 37/1364 72/10654 2.788510059243645e-15 1.4430539556585863e-14 6.384220398794661e-15 1147/3725/8945/5601/4790/5606/5594/6500/7316/4205/5519/5598/1432/4208/23291/5602/6195/10454/7189/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595/5515/5516 37 Human_papillomavirus_type_18 R-HSA-5696400 Dual Incision in GG-NER 27/1364 41/10654 3.6321376823969715e-15 1.8718319508452444e-14 8.281178729902683e-15 6118/5982/9557/8450/7316/9978/5111/1643/6119/1642/2965/5985/142/2068/2071/5984/6233/2067/51426/2968/7311/5983/6117/5981/10714/7314/8451 27 Human_papillomavirus_type_18 R-HSA-9022692 Regulation of MECP2 expression and activity 24/1364 33/10654 3.8058445192566015e-15 1.9532474764118588e-14 8.641369460861008e-15 27161/8841/2290/79718/9212/3930/57690/27327/192670/9611/28996/2874/9612/6907/3064/816/192669/3066/3065/23112/1385/25942/4343/26523 24 Human_papillomavirus_type_18 R-HSA-400253 Circadian Clock 36/1364 70/10654 6.435256495780307e-15 3.289131097843268e-14 1.455145718344085e-14 8945/8841/79718/1454/6500/3091/200186/6720/4209/7316/9611/5469/5501/8553/4208/1387/150094/2908/6907/2033/6256/5499/10498/6233/1385/7311/10499/23054/8864/1386/23411/1453/8648/10891/7314/5054 36 Human_papillomavirus_type_18 R-HSA-203927 MicroRNA (miRNA) biogenesis 20/1364 24/10654 7.882247126847511e-15 4.012193004731397e-14 1.7750358068224338e-14 27161/5434/5440/5430/5436/5441/192670/5438/5431/5435/54487/5433/5437/5439/192669/5901/29102/26523/5432/23405 20 Human_papillomavirus_type_18 R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 17/1364 18/10654 9.686142796350434e-15 4.9102813685988734e-14 2.172359415550989e-14 7027/25946/2810/5934/891/983/6790/5933/5111/1647/2033/995/1874/7157/10498/581/3276 17 Human_papillomavirus_type_18 R-HSA-73893 DNA Damage Bypass 29/1364 48/10654 9.831510366240968e-15 4.963713770272879e-14 2.1959984643465064e-14 6118/7320/5982/7706/8450/7316/9978/11201/5111/9100/7415/6119/51455/1642/5985/25898/7398/5984/57599/6233/51426/7311/5983/6117/5981/10714/7314/51514/8451 29 Human_papillomavirus_type_18 R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 51/1364 129/10654 1.4901461232478322e-14 7.49296147803161e-14 3.3149638880689046e-14 1147/3665/3725/8945/5601/351/4790/5606/7321/5336/5594/4214/6500/841/7316/5970/4792/4205/4793/8651/3146/5519/5598/1432/4208/23291/5602/6195/57162/10454/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 51 Human_papillomavirus_type_18 R-HSA-2559580 Oxidative Stress Induced Senescence 50/1364 125/10654 1.5608045140132097e-14 7.816609703243574e-14 3.458149220351849e-14 1912/3725/1019/5601/5606/1029/7027/2146/8535/6045/57690/5594/27327/80012/5931/7295/192670/8550/7316/1869/1911/4194/1031/5928/1432/84733/5602/23512/1021/57332/192669/7157/23135/23112/5609/6233/2353/1030/7311/4343/8726/5599/648/5600/23466/26523/7314/6015/5595/4193 50 Human_papillomavirus_type_18 R-HSA-170834 Signaling by TGF-beta Receptor Complex 36/1364 73/10654 3.491422373810991e-14 1.741504653925e-13 7.704597248485891e-14 57154/5590/7027/7321/6497/10273/4738/7316/9611/5501/9612/1024/6667/5933/4092/4609/4089/22938/8812/4088/1874/142/3065/9958/9040/4087/5499/6233/7514/1025/1030/7311/25937/7314/4221/5054 36 Human_papillomavirus_type_18 R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 22/1364 30/10654 4.1375824174186354e-14 2.0555509449735781e-13 9.093970618494854e-14 6118/7320/5982/8450/7316/9978/5111/6119/1642/5985/7398/5984/57599/6233/7311/5983/6117/5981/10714/7314/51514/8451 22 Human_papillomavirus_type_18 R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 27/1364 44/10654 4.8021083554195505e-14 2.3761827001717457e-13 1.0512478765061881e-13 7027/7321/6497/7316/9611/9612/1024/6667/5933/4092/4609/4089/22938/8812/4088/1874/142/3065/4087/6233/1025/1030/7311/25937/7314/4221/5054 27 Human_papillomavirus_type_18 R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 22/1364 31/10654 1.2533487790165477e-13 6.177218982295843e-13 2.732865758757886e-13 3725/5601/5594/4205/5519/5598/1432/4208/5602/6195/1385/2353/6196/5518/1386/6197/5599/5600/51231/5595/5515/5516 22 Human_papillomavirus_type_18 R-HSA-8986944 Transcriptional Regulation by MECP2 32/1364 62/10654 1.823010282544067e-13 8.949323205216329e-13 3.959273424123166e-13 27161/627/8841/2290/79718/5468/2904/9212/3930/57690/27327/6657/192670/54487/9611/28996/2874/4233/9612/4208/6907/3064/5728/816/192669/3066/3065/23112/1385/25942/4343/26523 32 Human_papillomavirus_type_18 R-HSA-168898 Toll-like Receptor Cascades 55/1364 155/10654 2.8969650869825183e-13 1.4165474952883023e-12 6.266953068399812e-13 1147/3665/3725/8945/5601/351/4790/5606/7184/7321/5336/5594/4214/6500/8411/841/7098/7316/5970/4792/4205/4793/6279/8651/3146/5519/5598/1432/4208/23291/5602/6195/57162/10454/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 55 Human_papillomavirus_type_18 R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 14/1364 14/10654 2.9982254153628124e-13 1.4546077991721145e-12 6.435335801066564e-13 1017/9134/1820/57060/25946/1027/898/1869/890/1026/7157/8900/144455/79733 14 Human_papillomavirus_type_18 R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 14/1364 14/10654 2.9982254153628124e-13 1.4546077991721145e-12 6.435335801066564e-13 23368/25946/5457/207/54971/10848/5458/10000/7157/8626/208/7161/7159/51230 14 Human_papillomavirus_type_18 R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 22/1364 32/10654 3.527277359171228e-13 1.7046219766889748e-12 7.541424458273116e-13 7027/7316/1024/6667/5933/4092/4609/4089/22938/8812/4088/1874/3065/4087/6233/1025/1030/7311/25937/7314/4221/5054 22 Human_papillomavirus_type_18 R-HSA-3232118 SUMOylation of transcription factors 17/1364 20/10654 4.75558691731463e-13 2.289317422986345e-12 1.0128177767597868e-12 7020/6670/7021/1029/9112/51588/3090/6613/7341/7022/7157/7329/7158/6612/9063/4193/8554 17 Human_papillomavirus_type_18 R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 43/1364 108/10654 1.3233345183791718e-12 6.34587440859819e-12 2.8074806689450424e-12 7124/7291/596/2309/7184/207/7422/4582/5743/3091/4318/4312/3383/58480/301/6097/6657/6778/3576/332/4313/6774/1026/6772/8651/4609/3552/79923/3717/598/2247/3320/595/7157/2353/604/6347/7431/3312/3569/3162/4170/4692 43 Human_papillomavirus_type_18 R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13/1364 13/10654 2.3615186265637133e-12 1.1280792823815891e-11 4.990739769499021e-12 7531/7532/10971/7533/2810/11200/7534/891/983/995/1111/7465/7529 13 Human_papillomavirus_type_18 R-HSA-9006936 Signaling by TGF-beta family members 41/1364 102/10654 3.0510995856644365e-12 1.4519025614541111e-11 6.423367548767235e-12 57154/5590/7027/9765/7321/6497/10273/4738/4086/130399/7316/9611/5501/9612/1024/6667/5933/4092/4609/4089/22938/8812/4088/1874/142/3065/9958/9040/4087/5499/6233/7514/1025/1030/7311/25937/4091/4090/7314/4221/5054 41 Human_papillomavirus_type_18 R-HSA-5655862 Translesion synthesis by POLK 15/1364 17/10654 4.01696850216408e-12 1.8969866462691205e-11 8.392465711945766e-12 6118/5982/7316/5111/6119/51455/5985/5984/6233/51426/7311/5983/6117/5981/7314 15 Human_papillomavirus_type_18 R-HSA-5656121 Translesion synthesis by POLI 15/1364 17/10654 4.01696850216408e-12 1.8969866462691205e-11 8.392465711945766e-12 6118/5982/7316/11201/5111/6119/51455/5985/5984/6233/7311/5983/6117/5981/7314 15 Human_papillomavirus_type_18 R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 114/1364 473/10654 4.571177890421099e-12 2.1505314166299258e-11 9.51417407814918e-12 627/5434/5440/5590/4893/857/5290/85440/5241/1499/2904/5747/3815/5430/10048/10273/207/5436/7422/5594/3315/5908/3178/51741/4318/2064/5441/6778/5438/5431/6696/6776/5435/7316/5433/1950/9611/3185/6774/4205/4233/6772/6714/2099/8651/3910/5519/5898/5598/1432/4208/5437/5159/4670/2567/4067/3717/2247/10000/3320/4846/6195/8471/5439/1111/2264/5603/3630/998/2066/83737/3481/3925/6285/208/6233/1398/5867/3187/5580/2475/1385/6196/7311/3479/5518/1213/3791/1956/1211/60/8851/581/6197/3845/5600/6777/3265/6300/1020/7057/5432/3480/5663/10254/51231/7529/5156/7314/5595/5515/6387/5516/5607 114 Human_papillomavirus_type_18 R-HSA-8953750 Transcriptional Regulation by E2F6 22/1364 35/10654 5.491711969934749e-12 2.573851421380739e-11 1.1386985693370164e-11 23468/5888/7027/2146/6045/80012/5931/79813/1869/1911/5928/23512/1111/672/5932/8726/648/317/23429/10919/6015/6241 22 Human_papillomavirus_type_18 R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 23/1364 38/10654 5.603766965699367e-12 2.6164957035333138e-11 1.1575648421428848e-11 1912/6597/1459/8535/6045/80012/1460/6598/6599/86/28996/1457/1911/6603/84733/8289/2033/6602/57332/648/23466/23429/6015 23 Human_papillomavirus_type_18 R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 19/1364 27/10654 7.818094409697092e-12 3.6231616630014135e-11 1.6029243055231274e-11 5434/5440/902/5430/5436/5441/5438/5431/5435/5433/4331/5437/2965/2068/5439/2071/2968/1022/5432 19 Human_papillomavirus_type_18 R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 19/1364 27/10654 7.818094409697092e-12 3.6231616630014135e-11 1.6029243055231274e-11 5434/5440/902/5430/5436/5441/5438/5431/5435/5433/4331/5437/2965/2068/5439/2071/2968/1022/5432 19 Human_papillomavirus_type_18 R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 28/1364 55/10654 9.237142339603915e-12 4.236091161633825e-11 1.8740906741019216e-11 1147/834/596/351/4790/842/58484/7295/841/7316/5970/7128/1432/598/10628/5603/10454/83737/7189/6233/3326/7311/5600/7334/1540/3551/6300/7314 28 Human_papillomavirus_type_18 R-HSA-5617472 Activation of anterior HOX genes in hindbrain development during early embryogenesis 45/1364 122/10654 9.243000843822598e-12 4.236091161633825e-11 1.8740906741019216e-11 9070/3725/5434/5440/8841/11091/2146/5430/8085/5436/5929/5931/5915/5441/5438/5431/7403/5435/5433/9611/9935/10664/3200/5928/5087/22976/1387/5437/2033/23512/3211/5439/6256/58508/23054/9063/5914/8726/57472/5080/5316/3201/8202/5432/7528 45 Human_papillomavirus_type_18 R-HSA-5619507 Activation of HOX genes during differentiation 45/1364 122/10654 9.243000843822598e-12 4.236091161633825e-11 1.8740906741019216e-11 9070/3725/5434/5440/8841/11091/2146/5430/8085/5436/5929/5931/5915/5441/5438/5431/7403/5435/5433/9611/9935/10664/3200/5928/5087/22976/1387/5437/2033/23512/3211/5439/6256/58508/23054/9063/5914/8726/57472/5080/5316/3201/8202/5432/7528 45 Human_papillomavirus_type_18 R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 16/1364 20/10654 1.4066473963223666e-11 6.423000243501394e-11 2.8416019383911592e-11 2648/23462/55534/84441/10046/22938/8850/1387/4088/59/2033/4855/9794/23493/3516/4851 16 Human_papillomavirus_type_18 R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 12/1364 12/10654 1.8588225757315814e-11 8.456621388493128e-11 3.741297029234184e-11 23368/8793/3486/355/8794/124446/8797/7157/8626/7161/7159/8795 12 Human_papillomavirus_type_18 R-HSA-4551638 SUMOylation of chromatin organization proteins 32/1364 71/10654 1.9993308926145354e-11 9.062660469442529e-11 4.009415005550471e-11 1912/23468/5903/7175/9631/8535/6045/80012/6613/23636/9759/1911/4927/9688/7341/84733/23225/23512/57332/3066/3065/1107/7329/9972/6612/9063/8021/6396/648/8480/6015/8554 32 Human_papillomavirus_type_18 R-HSA-110312 Translesion synthesis by REV1 14/1364 16/10654 2.796390640839111e-11 1.2629517003353368e-10 5.5874293378680034e-11 6118/5982/7316/5111/6119/51455/5985/5984/6233/7311/5983/6117/5981/7314 14 Human_papillomavirus_type_18 R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 13/1364 14/10654 2.9163567731920196e-11 1.3123605479364088e-10 5.8060192052106574e-11 23368/79370/9540/332/64065/5876/7157/8626/604/7161/7159/10397/5875 13 Human_papillomavirus_type_18 R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 18/1364 26/10654 4.3580502536375644e-11 1.9540427491039187e-10 8.644887829750366e-11 80010/83990/5888/9156/1763/7486/10111/675/472/580/116028/641/10524/4683/79728/672/5932/7156 18 Human_papillomavirus_type_18 R-HSA-72086 mRNA Capping 19/1364 29/10654 5.463961574917023e-11 2.4410936244773175e-10 1.0799651427893548e-10 5434/5440/902/5430/5436/5441/5438/5431/5435/5433/4331/5437/2965/2068/5439/2071/2968/1022/5432 19 Human_papillomavirus_type_18 R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 25/1364 48/10654 6.333824466284136e-11 2.8195734720877767e-10 1.2474085536315106e-10 5434/5440/902/5430/5436/6749/5441/5438/5431/5435/5433/4331/5437/8812/2965/2068/5439/2071/2968/1025/11198/51497/1022/5432/8178 25 Human_papillomavirus_type_18 R-HSA-110320 Translesion Synthesis by POLH 15/1364 19/10654 8.891020366586385e-11 3.9438026054643893e-10 1.7447791847210876e-10 6118/5982/7316/5111/7415/6119/5985/25898/5984/6233/7311/5983/6117/5981/7314 15 Human_papillomavirus_type_18 R-HSA-113418 Formation of the Early Elongation Complex 20/1364 33/10654 1.3436311379967427e-10 5.917694586496292e-10 2.6180494738122424e-10 5434/5440/902/5430/5436/5441/5438/5431/5435/5433/4331/5437/2965/2068/5439/2071/2968/51497/1022/5432 20 Human_papillomavirus_type_18 R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 20/1364 33/10654 1.3436311379967427e-10 5.917694586496292e-10 2.6180494738122424e-10 5434/5440/902/5430/5436/5441/5438/5431/5435/5433/4331/5437/2965/2068/5439/2071/2968/51497/1022/5432 20 Human_papillomavirus_type_18 R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 14/1364 17/10654 1.397162833041168e-10 6.131718157728377e-10 2.7127357219545834e-10 857/2290/2309/57060/4303/1027/5934/1026/901/4089/1647/9314/4088/4087 14 Human_papillomavirus_type_18 R-HSA-167169 HIV Transcription Elongation 24/1364 46/10654 1.4615640731805595e-10 6.347071954161731e-10 2.8080104755254036e-10 5434/5440/902/5430/5436/6749/5441/5438/5431/5435/5433/4331/5437/2965/2068/5439/2071/2968/1025/11198/51497/1022/5432/8178 24 Human_papillomavirus_type_18 R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 24/1364 46/10654 1.4615640731805595e-10 6.347071954161731e-10 2.8080104755254036e-10 5434/5440/902/5430/5436/6749/5441/5438/5431/5435/5433/4331/5437/2965/2068/5439/2071/2968/1025/11198/51497/1022/5432/8178 24 Human_papillomavirus_type_18 R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 24/1364 46/10654 1.4615640731805595e-10 6.347071954161731e-10 2.8080104755254036e-10 5434/5440/902/5430/5436/6749/5441/5438/5431/5435/5433/4331/5437/2965/2068/5439/2071/2968/1025/11198/51497/1022/5432/8178 24 Human_papillomavirus_type_18 R-HSA-168325 Viral Messenger RNA Synthesis 23/1364 43/10654 1.8305418213218287e-10 7.92171756822896e-10 3.504650030185199e-10 5434/5440/5903/7175/9631/5430/5436/5441/23636/5438/5431/5435/5433/4927/9688/5437/23225/5439/9972/8021/6396/5432/8480 23 Human_papillomavirus_type_18 R-HSA-111447 Activation of BAD and translocation to mitochondria 13/1364 15/10654 1.9295582703432655e-10 8.321220040855333e-10 3.6813940684180725e-10 596/7531/7532/207/10971/7533/2810/7534/10000/5534/208/637/7529 13 Human_papillomavirus_type_18 R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 17/1364 25/10654 2.3892890423433986e-10 1.026815567678374e-9 4.542738590796774e-10 1017/902/2305/891/890/4331/983/5519/995/8900/7514/5518/5347/7465/1022/5515/5516 17 Human_papillomavirus_type_18 R-HSA-4570464 SUMOylation of RNA binding proteins 24/1364 47/10654 2.6264849229279505e-10 1.1248600945781086e-9 4.976497748705591e-10 1912/5903/7175/9631/8535/6045/80012/6613/23636/3190/1911/4927/9688/7341/84733/23225/57332/7329/9972/8021/6396/648/8480/6015 24 Human_papillomavirus_type_18 R-HSA-5654738 Signaling by FGFR2 31/1364 73/10654 2.6474371790564516e-10 1.1299371052880112e-9 4.998958970763131e-10 5434/5440/4893/5290/5430/5436/5594/3178/5441/5438/5431/5435/7316/5433/3185/6714/5437/4670/2247/5439/6233/3187/7311/5518/3845/3265/5432/7314/5595/5515/5516 31 Human_papillomavirus_type_18 R-HSA-9009391 Extra-nuclear estrogen signaling 32/1364 77/10654 2.678995119026806e-10 1.139490389668251e-9 5.041223691896152e-10 596/5590/4893/857/5290/2309/5747/207/5594/1027/3315/4318/2100/4313/1950/6714/2099/10000/3320/4846/595/2783/208/7514/1385/2353/1956/3845/3276/3265/3480/5595 32 Human_papillomavirus_type_18 R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 28/1364 63/10654 5.415586112012099e-10 2.29561704816349e-9 1.0156047962889586e-9 1147/3665/5434/5440/4790/1499/7520/5441/51082/6778/7098/5591/5435/7316/5970/4792/4793/3428/1387/5437/2033/22954/1660/6233/7311/3551/2547/7314 28 Human_papillomavirus_type_18 R-HSA-4615885 SUMOylation of DNA replication proteins 23/1364 45/10654 6.069125733926271e-10 2.56389597331171e-9 1.1342941758358444e-9 7150/5903/7175/9631/9212/51588/7153/6613/23636/332/6790/5111/4927/9688/7341/23225/7329/9972/6612/7155/8021/6396/8480 23 Human_papillomavirus_type_18 R-HSA-5656169 Termination of translesion DNA synthesis 19/1364 32/10654 6.462405880009803e-10 2.720782407787178e-9 1.2037023619500864e-9 6118/5982/7706/7316/11201/5111/9100/6119/51455/5985/5984/6233/51426/7311/5983/6117/5981/10714/7314 19 Human_papillomavirus_type_18 R-HSA-9012852 Signaling by NOTCH3 24/1364 49/10654 7.962858008990963e-10 3.3411721780968834e-9 1.4781692321099867e-9 2648/23462/4904/55534/84441/10046/7316/1950/4854/6772/22938/8850/5087/1387/2033/9794/6233/23493/7311/1956/3516/4851/5663/7314 24 Human_papillomavirus_type_18 R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 33/1364 84/10654 8.225430904867619e-10 3.4397256511264586e-9 1.5217703109483952e-9 7124/1019/8841/4790/79718/5468/9440/6721/1051/6720/6837/3952/688/9611/5469/5970/9612/1024/9314/1387/6907/2033/9967/6256/10498/112950/10499/23054/9412/8202/8648/23097/10891 33 Human_papillomavirus_type_18 R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 21/1364 39/10654 9.709899691771272e-10 4.046877656771785e-9 1.7903806566953744e-9 6118/5982/7706/7316/11201/5111/9100/7415/6119/51455/5985/25898/5984/6233/51426/7311/5983/6117/5981/10714/7314 21 Human_papillomavirus_type_18 R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 10/1364 10/10654 1.1494508493126698e-9 4.742916793509421e-9 2.098315591331399e-9 5563/51422/53632/1432/5571/5600/5564/6300/5565/10891 10 Human_papillomavirus_type_18 R-HSA-390450 Folding of actin by CCT/TriC 10/1364 10/10654 1.1494508493126698e-9 4.742916793509421e-9 2.098315591331399e-9 10694/10575/7203/10576/908/6950/10574/60/22948/10693 10 Human_papillomavirus_type_18 R-HSA-450341 Activation of the AP-1 family of transcription factors 10/1364 10/10654 1.1494508493126698e-9 4.742916793509421e-9 2.098315591331399e-9 3725/5601/5594/1432/5602/2353/1386/5599/5600/5595 10 Human_papillomavirus_type_18 R-HSA-112382 Formation of RNA Pol II elongation complex 27/1364 61/10654 1.2335274530133222e-9 5.056241243044707e-9 2.2369335781586044e-9 5434/5440/902/6830/5430/5436/6749/5441/5438/5431/5435/5433/4331/5437/8812/2965/2068/5439/2071/2968/1025/11198/51497/1022/5432/8178/55840 27 Human_papillomavirus_type_18 R-HSA-75955 RNA Polymerase II Transcription Elongation 27/1364 61/10654 1.2335274530133222e-9 5.056241243044707e-9 2.2369335781586044e-9 5434/5440/902/6830/5430/5436/6749/5441/5438/5431/5435/5433/4331/5437/8812/2965/2068/5439/2071/2968/1025/11198/51497/1022/5432/8178/55840 27 Human_papillomavirus_type_18 R-HSA-3371568 Attenuation phase 12/1364 14/10654 1.3181795728928607e-9 5.367800096829289e-9 2.3747704471098303e-9 3303/3337/3305/1387/3320/2033/3326/3306/3304/3312/2288/10728 12 Human_papillomavirus_type_18 R-HSA-8941856 RUNX3 regulates NOTCH signaling 12/1364 14/10654 1.3181795728928607e-9 5.367800096829289e-9 2.3747704471098303e-9 2648/864/55534/84441/10046/22938/8850/1387/2033/9794/3516/4851 12 Human_papillomavirus_type_18 R-HSA-4090294 SUMOylation of intracellular receptors 18/1364 30/10654 1.4499832224977123e-9 5.885226020726008e-9 2.603685043494344e-9 7068/5241/5468/51588/6613/9759/8856/2099/7341/2908/6256/7329/367/6612/9063/5914/7421/8554 18 Human_papillomavirus_type_18 R-HSA-198753 ERK/MAPK targets 15/1364 22/10654 2.678687578333785e-9 1.0836905447200523e-8 4.7943593893030535e-9 5594/4205/5519/5598/1432/4208/6195/6196/5518/6197/5600/51231/5595/5515/5516 15 Human_papillomavirus_type_18 R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 16/1364 25/10654 3.148431768396082e-9 1.261403953660624e-8 5.580581946019542e-9 5594/4205/5519/5598/1432/4208/6195/1385/6196/5518/6197/5600/51231/5595/5515/5516 16 Human_papillomavirus_type_18 R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 16/1364 25/10654 3.148431768396082e-9 1.261403953660624e-8 5.580581946019542e-9 6118/7515/5982/7316/5111/6119/5985/5984/6233/51426/7311/5983/6117/5981/10714/7314 16 Human_papillomavirus_type_18 R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 16/1364 25/10654 3.148431768396082e-9 1.261403953660624e-8 5.580581946019542e-9 2648/23462/55534/84441/10046/4854/6772/22938/8850/5087/1387/2033/9794/23493/3516/4851 16 Human_papillomavirus_type_18 R-HSA-4655427 SUMOylation of DNA methylation proteins 13/1364 17/10654 3.404585549018458e-9 1.3596447755244131e-8 6.015209533212507e-9 1912/1788/8535/1786/6045/80012/1911/7341/84733/57332/7329/648/6015 13 Human_papillomavirus_type_18 R-HSA-3232142 SUMOylation of ubiquitinylation proteins 20/1364 38/10654 4.1559410323361415e-9 1.6490986460579834e-8 7.295783483704275e-9 5903/7175/9631/51588/23636/4927/9688/7341/23225/7428/7329/5987/5371/9972/9063/8021/6396/8480/4193/8554 20 Human_papillomavirus_type_18 R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 20/1364 38/10654 4.1559410323361415e-9 1.6490986460579834e-8 7.295783483704275e-9 7020/7021/3815/7422/4869/4839/51741/2064/1026/2099/4609/3329/10370/7341/1387/2033/7022/7329/1956/7528 20 Human_papillomavirus_type_18 R-HSA-8941326 RUNX2 regulates bone development 18/1364 32/10654 6.128414653398956e-9 2.424041719592835e-8 1.0724212031760828e-8 25/8841/23462/5594/4086/5925/10013/4094/9759/6714/4089/23493/25937/367/860/10432/4091/5595 18 Human_papillomavirus_type_18 R-HSA-6803529 FGFR2 alternative splicing 16/1364 26/10654 7.213250070367732e-9 2.84408145631642e-8 1.258251140094221e-8 5434/5440/5430/5436/3178/5441/5438/5431/5435/5433/3185/5437/4670/5439/3187/5432 16 Human_papillomavirus_type_18 R-HSA-1592230 Mitochondrial biogenesis 34/1364 95/10654 7.899939925214853e-9 3.1049763883281164e-8 1.3736737644777326e-8 5563/5442/8841/79718/23408/23410/51422/200186/53632/3313/4209/9611/5469/23409/54205/1432/5571/4208/1387/6907/6648/6256/10498/1385/10499/23054/1386/5600/5564/6300/5565/7019/8648/10891 34 Human_papillomavirus_type_18 R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 30/1364 78/10654 8.671112366613703e-9 3.397325413039186e-8 1.503012005768671e-8 1147/3665/351/4790/7321/4214/841/7706/7316/5970/4792/4793/3093/3146/7128/1387/843/2033/54941/83737/7189/6285/51191/6233/7311/55593/5300/1540/3551/7314 30 Human_papillomavirus_type_18 R-HSA-209560 NF-kB is activated and signals survival 11/1364 13/10654 8.902836307726442e-9 3.4771455013195725e-8 1.5383252408583925e-8 4804/4790/8878/7316/5970/4792/7189/6233/7311/3551/7314 11 Human_papillomavirus_type_18 R-HSA-8848021 Signaling by PTK6 24/1364 54/10654 9.300244231392038e-9 3.609657292309035e-8 1.5969498318377118e-8 120892/1017/1019/4893/207/27043/1027/898/3091/2064/10657/7316/1950/6774/2908/595/2066/6233/1398/7311/1956/3845/3265/7314 24 Human_papillomavirus_type_18 R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 24/1364 54/10654 9.300244231392038e-9 3.609657292309035e-8 1.5969498318377118e-8 120892/1017/1019/4893/207/27043/1027/898/3091/2064/10657/7316/1950/6774/2908/595/2066/6233/1398/7311/1956/3845/3265/7314 24 Human_papillomavirus_type_18 R-HSA-168638 NOD1/2 Signaling Pathway 19/1364 36/10654 9.606999006953169e-9 3.717100550353843e-8 1.64448384378736e-8 1147/834/842/841/7316/7128/1432/5603/10454/83737/7189/6233/7311/5600/7334/1540/3551/6300/7314 19 Human_papillomavirus_type_18 R-HSA-190236 Signaling by FGFR 32/1364 87/10654 1.0067248561470354e-8 3.883081587995708e-8 1.7179155766876513e-8 5434/5440/4893/5290/5430/5436/5594/3178/5441/5438/5431/5435/7316/5433/3185/6714/5437/4670/2247/5439/2264/6233/3187/7311/5518/3845/3265/5432/7314/5595/5515/5516 32 Human_papillomavirus_type_18 R-HSA-9614399 Regulation of localization of FOXO transcription factors 10/1364 11/10654 1.1181768014020176e-8 4.299614821490111e-8 1.9021942002015748e-8 2309/7532/207/10971/4303/2810/7534/10000/208/7529 10 Human_papillomavirus_type_18 R-HSA-5693568 Resolution of D-loop Structures through Holliday Junction Intermediates 18/1364 33/10654 1.1873394502462975e-8 4.551467892610807e-8 2.0136166115288085e-8 80010/83990/5888/9156/1763/7486/10111/675/472/580/116028/641/10524/4683/79728/672/5932/7156 18 Human_papillomavirus_type_18 R-HSA-166520 Signaling by NTRKs 35/1364 101/10654 1.255595851145664e-8 4.798307837301276e-8 2.122821163718337e-8 627/4893/5290/2904/5594/6774/4205/6714/5519/5898/5598/1432/4208/6195/5603/1398/1385/6196/5518/1213/1211/8851/581/6197/3845/5600/3265/6300/1020/51231/7529/5595/5515/5516/5607 35 Human_papillomavirus_type_18 R-HSA-1538133 G0 and Early G1 16/1364 27/10654 1.5602405302684732e-8 5.944229259489092e-8 2.6297886884085988e-8 1017/9134/7027/7153/898/5934/1869/890/983/5933/5111/4609/5928/1874/3065/8900 16 Human_papillomavirus_type_18 R-HSA-3371571 HSF1-dependent transactivation 15/1364 24/10654 1.5959389138790824e-8 6.043158936090916e-8 2.6735562036100162e-8 3303/1410/3337/3305/1387/3320/2033/816/3326/2475/3306/3304/3312/2288/10728 15 Human_papillomavirus_type_18 R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 15/1364 24/10654 1.5959389138790824e-8 6.043158936090916e-8 2.6735562036100162e-8 596/2309/5747/207/5594/1027/1950/10000/595/208/7514/1385/2353/1956/5595 15 Human_papillomavirus_type_18 R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 30/1364 80/10654 1.7282738870607018e-8 6.504336166139563e-8 2.8775857943256648e-8 3837/3838/5903/7175/9631/2316/23636/7706/9470/7316/6772/4927/9688/6041/3840/6059/23225/1973/51191/6233/7311/9972/5610/5300/8021/6396/7334/8480/7314/5595 30 Human_papillomavirus_type_18 R-HSA-187037 Signaling by NTRK1 (TRKA) 30/1364 80/10654 1.7282738870607018e-8 6.504336166139563e-8 2.8775857943256648e-8 4893/5290/5594/6774/4205/6714/5519/5898/5598/1432/4208/6195/5603/1398/1385/6196/5518/1213/1211/6197/3845/5600/3265/6300/51231/7529/5595/5515/5516/5607 30 Human_papillomavirus_type_18 R-HSA-176187 Activation of ATR in response to replication stress 19/1364 37/10654 1.7386792328166946e-8 6.504336166139563e-8 2.8775857943256648e-8 1017/6118/5883/5982/63967/545/84515/6119/3364/144715/5985/995/84126/1111/5984/5983/6117/5884/5810 19 Human_papillomavirus_type_18 R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 19/1364 37/10654 1.7386792328166946e-8 6.504336166139563e-8 2.8775857943256648e-8 27161/8841/79718/57690/27327/192670/9611/2874/9612/6907/2033/192669/23028/6256/23112/4343/1071/26523/8648 19 Human_papillomavirus_type_18 R-HSA-9614657 FOXO-mediated transcription of cell death genes 12/1364 16/10654 2.055253577606808e-8 7.6655403705335e-8 3.391314580403837e-8 27113/2309/10018/4802/4303/4800/10370/1387/6794/2033/4801/604 12 Human_papillomavirus_type_18 R-HSA-5693537 Resolution of D-Loop Structures 18/1364 34/10654 2.222078827013003e-8 8.262939829790867e-8 3.655610298458202e-8 80010/83990/5888/9156/1763/7486/10111/675/472/580/116028/641/10524/4683/79728/672/5932/7156 18 Human_papillomavirus_type_18 R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 24/1364 56/10654 2.234141995184275e-8 8.282998083638416e-8 3.6644842780398795e-8 5442/8841/79718/23408/23410/200186/4209/9611/5469/23409/54205/4208/1387/6907/6648/6256/10498/1385/10499/23054/1386/7019/8648/10891 24 Human_papillomavirus_type_18 R-HSA-8851708 Signaling by FGFR2 IIIa TM 13/1364 19/10654 3.022277962213858e-8 1.1171634610326224e-7 4.9424470434700304e-8 5434/5440/5430/5436/5441/5438/5431/5435/5433/5437/2247/5439/5432 13 Human_papillomavirus_type_18 R-HSA-5696394 DNA Damage Recognition in GG-NER 19/1364 38/10654 3.061764362399778e-8 1.1284009905342803e-7 4.992163039739761e-8 9318/86/8450/7316/9978/1643/1642/142/10987/6233/2873/7311/60/5886/7508/7314/51138/8451/7528 19 Human_papillomavirus_type_18 R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 15/1364 25/10654 3.51758251943828e-8 1.2887426221658833e-7 5.7015310515348005e-8 10694/51807/10575/7277/7203/10576/908/6950/7846/10574/10383/84790/22948/10693/7280 15 Human_papillomavirus_type_18 R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 15/1364 25/10654 3.51758251943828e-8 1.2887426221658833e-7 5.7015310515348005e-8 1147/2309/842/207/4303/1027/7249/1026/2932/3164/10000/208/2475/1385/4193 15 Human_papillomavirus_type_18 R-HSA-198323 AKT phosphorylates targets in the cytosol 11/1364 14/10654 3.671324433544965e-8 1.341113219547896e-7 5.933224007153163e-8 1147/842/207/1027/7249/1026/2932/10000/208/23608/4193 11 Human_papillomavirus_type_18 R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 20/1364 42/10654 3.817724838442301e-8 1.3905027124179876e-7 6.151728247158145e-8 9070/8945/1487/1499/207/8085/5929/6657/7534/7316/3065/208/57680/6233/7514/7311/331/6659/7314/4221 20 Human_papillomavirus_type_18 R-HSA-73863 RNA Polymerase I Transcription Termination 17/1364 32/10654 5.1431440604963564e-8 1.8677733693381505e-7 8.263223144287774e-8 5434/5440/902/9015/9014/5441/51082/5435/4331/9013/5437/2965/2068/2071/2968/6908/1022 17 Human_papillomavirus_type_18 R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 31/1364 88/10654 5.4933620043587626e-8 1.9891415770885082e-7 8.80016868582254e-8 115106/8945/22995/22981/7531/4659/203068/7532/1454/6500/7277/7316/891/983/6790/23291/7846/7283/3320/10540/6233/7311/54930/5518/10383/55835/5347/9662/1453/8481/7314 31 Human_papillomavirus_type_18 R-HSA-3371511 HSF1 activation 10/1364 12/10654 5.9339812530258534e-8 2.1362332510893073e-7 9.450917510540032e-8 6118/7531/1915/10013/7415/6119/3320/3326/6117/10728 10 Human_papillomavirus_type_18 R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 10/1364 12/10654 5.9339812530258534e-8 2.1362332510893073e-7 9.450917510540032e-8 834/58484/55367/472/843/7157/8626/7161/839/317 10 Human_papillomavirus_type_18 R-HSA-8934593 Regulation of RUNX1 Expression and Activity 12/1364 17/10654 6.170761632098659e-8 2.215053741926744e-7 9.799627538653788e-8 27161/57690/27327/192670/6714/1021/595/192669/5371/23112/4343/26523 12 Human_papillomavirus_type_18 R-HSA-167287 HIV elongation arrest and recovery 18/1364 36/10654 7.097835523626117e-8 2.5331930230872525e-7 1.1207108721514924e-7 5434/5440/5430/5436/6749/5441/5438/5431/5435/5433/5437/8812/5439/1025/11198/51497/5432/8178 18 Human_papillomavirus_type_18 R-HSA-167290 Pausing and recovery of HIV elongation 18/1364 36/10654 7.097835523626117e-8 2.5331930230872525e-7 1.1207108721514924e-7 5434/5440/5430/5436/6749/5441/5438/5431/5435/5433/5437/8812/5439/1025/11198/51497/5432/8178 18 Human_papillomavirus_type_18 R-HSA-1226099 Signaling by FGFR in disease 25/1364 63/10654 7.274886388797138e-8 2.588942376758179e-7 1.1453749645459527e-7 8805/5434/5440/4893/5290/5430/5436/613/5441/5438/5431/6776/5435/5433/6774/6772/5437/2247/5439/2264/3845/6777/3265/5432/7750 25 Human_papillomavirus_type_18 R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 23/1364 55/10654 7.638257271446737e-8 2.710490151753385e-7 1.1991489611113373e-7 3303/5241/51807/10294/7277/3337/3305/832/7846/2908/3320/3301/10540/3326/3306/367/10383/84790/3304/3312/7280/2288/10728 23 Human_papillomavirus_type_18 R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 9/1364 10/10654 7.995681904204073e-8 2.8292412891799026e-7 1.2516856962046865e-7 2309/4303/23410/7295/8850/1387/10628/2033/23411 9 Human_papillomavirus_type_18 R-HSA-1169408 ISG15 antiviral mechanism 27/1364 72/10654 8.9187487495195707e-008 3.137984687508019e-7 1.3882769784551114e-7 3837/3838/5903/7175/9631/23636/7706/9470/7316/6772/4927/9688/3840/23225/1973/51191/6233/7311/9972/5610/5300/8021/6396/7334/8480/7314/5595 27 Human_papillomavirus_type_18 R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 27/1364 72/10654 8.9187487495195707e-008 3.137984687508019e-7 1.3882769784551114e-7 5563/7531/4627/51807/7532/207/10971/51422/7533/2810/7277/53632/7534/4641/5898/5571/7846/208/5867/9882/10383/60/84790/5564/5565/7280/7529 27 Human_papillomavirus_type_18 R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 37/1364 119/10654 1.2532359714562557e-7 4.396946543922795e-7 1.9452547639017708e-7 8841/79718/5468/9440/4802/6721/1543/6720/6837/9611/5469/2874/4800/9612/1024/6667/23309/1387/6907/2033/9967/4801/6256/10498/183/2274/112950/10499/23054/25942/9412/405/8202/8648/23097/10891/7296 37 Human_papillomavirus_type_18 R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 17/1364 34/10654 1.6470294090761252e-7 5.746096983349852e-7 2.542132914067822e-7 5434/5440/5430/5436/6749/5441/5438/5431/5435/5433/5437/5439/1025/11198/51497/5432/8178 17 Human_papillomavirus_type_18 R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 17/1364 34/10654 1.6470294090761252e-7 5.746096983349852e-7 2.542132914067822e-7 5434/5440/5430/5436/6749/5441/5438/5431/5435/5433/5437/5439/1025/11198/51497/5432/8178 17 Human_papillomavirus_type_18 R-HSA-6807505 RNA polymerase II transcribes snRNA genes 27/1364 74/10654 1.72336383848286e-7 5.995568312032808e-7 2.6525016178329734e-7 6884/5434/5440/55197/5430/5436/6878/5441/5438/5431/5435/5433/6667/5437/8812/64859/5439/1025/6880/6908/80237/79035/6882/1022/5432/8178/6877 27 Human_papillomavirus_type_18 R-HSA-186712 Regulation of beta-cell development 19/1364 42/10654 2.3271450577990655e-7 8.073503245213518e-7 3.5718015882714267e-7 2648/3172/3171/207/55534/84441/10046/22938/8850/1387/10000/2033/3630/6514/208/9794/5080/3516/4851 19 Human_papillomavirus_type_18 R-HSA-1236394 Signaling by ERBB4 23/1364 58/10654 2.4531438231203606e-7 8.486920970238128e-7 3.754701878518775e-7 4893/5290/5241/51741/6776/7316/1950/9611/6714/2099/2567/2066/83737/3925/6285/6233/7311/1956/3845/3265/5663/7314/6387 23 Human_papillomavirus_type_18 R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 15/1364 28/10654 2.762289812884365e-7 9.503501239895793e-7 4.2044475355755616e-7 10694/10575/7277/7203/10576/908/6950/7846/10574/10383/60/84790/22948/10693/7280 15 Human_papillomavirus_type_18 R-HSA-69205 G1/S-Specific Transcription 15/1364 28/10654 2.762289812884365e-7 9.503501239895793e-7 4.2044475355755616e-7 7027/898/5934/5422/1869/983/5933/5111/5928/1874/3065/8900/1719/7083/6241 15 Human_papillomavirus_type_18 R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 18/1364 39/10654 3.3336480797810964e-7 1.1437543964331827e-6 5.060088100162061e-7 10694/9134/8841/8237/10575/898/7203/10576/908/6774/26272/6950/55294/10238/7157/10574/22948/10693 18 Human_papillomavirus_type_18 R-HSA-429947 Deadenylation of mRNA 14/1364 25/10654 3.353921999349465e-7 1.147540254322875e-6 5.076837128201888e-7 9924/4849/4850/26986/9337/25904/246175/4848/23019/1973/55571/57472/85456/29883 14 Human_papillomavirus_type_18 R-HSA-1852241 Organelle biogenesis and maintenance 69/1364 296/10654 3.40881709768428e-7 1.1631183613527131e-6 5.145756289737404e-7 115106/10694/5563/22995/5442/8841/79718/22981/7531/203068/51807/7532/10575/1454/23408/23410/51422/7277/200186/10013/53632/3313/4209/7203/10576/9611/5469/23409/983/54205/5310/1432/5571/4208/1387/6950/7846/6907/7283/3320/10540/6648/6256/10498/1385/54930/10499/23054/5518/10383/1386/55835/5347/403/23322/84790/22948/378/5600/9662/1453/5564/6300/5565/7019/8648/8481/7280/10891 69 Human_papillomavirus_type_18 R-HSA-193639 p75NTR signals via NF-kB 11/1364 16/10654 3.44135497222369e-7 1.1678040643447604e-6 5.166486325857827e-7 4804/4790/8878/7316/5970/4792/7189/6233/7311/3551/7314 11 Human_papillomavirus_type_18 R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 11/1364 16/10654 3.44135497222369e-7 1.1678040643447604e-6 5.166486325857827e-7 2648/55534/84441/10046/22938/8850/1387/2033/9794/3516/4851 11 Human_papillomavirus_type_18 R-HSA-438064 Post NMDA receptor activation events 28/1364 81/10654 3.7715070826623785e-7 1.2763519881925542e-6 5.646713601462101e-7 5563/3838/4893/2904/51807/5594/51422/7277/53632/6714/5571/7846/6195/816/2066/1385/6196/5562/10383/84790/8536/6197/3845/3265/5564/5565/7280/5595 28 Human_papillomavirus_type_18 R-HSA-9613829 Chaperone Mediated Autophagy 13/1364 22/10654 3.8098721858948844e-7 1.2843746850223565e-6 5.682206844492501e-7 1915/1080/10013/7316/3043/3320/6233/3326/7311/7431/3312/11315/7314 13 Human_papillomavirus_type_18 R-HSA-2173789 TGF-beta receptor signaling activates SMADs 16/1364 32/10654 3.8262369843661186e-7 1.2843746850223565e-6 5.682206844492501e-7 57154/10273/4738/7316/5501/4092/4089/4088/9958/9040/4087/5499/6233/7514/7311/7314 16 Human_papillomavirus_type_18 R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 16/1364 32/10654 3.8262369843661186e-7 1.2843746850223565e-6 5.682206844492501e-7 10694/51807/10575/7277/7203/10576/908/6950/7846/10574/10383/60/84790/22948/10693/7280 16 Human_papillomavirus_type_18 R-HSA-9024446 NR1H2 and NR1H3-mediated signaling 20/1364 47/10654 3.8370770897286433e-7 1.2845417103619878e-6 5.682945781921838e-7 27161/8841/79718/57690/27327/6720/192670/9611/2874/9612/6907/2033/192669/23028/6256/23112/4343/1071/26523/8648 20 Human_papillomavirus_type_18 R-HSA-73854 RNA Polymerase I Promoter Clearance 34/1364 110/10654 4.7115093987605547e-7 1.573036202489411e-6 6.959275342821193e-7 5434/5440/902/9015/2648/2074/9112/9219/9014/5931/5441/51082/5435/4331/9013/1108/8850/5928/5437/57459/2965/54815/2068/3066/3065/2071/1107/2968/57504/6908/53615/1022/10919/5595 34 Human_papillomavirus_type_18 R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 15/1364 29/10654 5.046043748720897e-7 1.680210813917253e-6 7.43342694181546e-7 2309/4303/23410/4287/6720/4089/4088/2908/3630/3066/3065/6648/4087/25942/10891 15 Human_papillomavirus_type_18 R-HSA-5250913 Positive epigenetic regulation of rRNA expression 33/1364 106/10654 5.762551608885987e-7 1.9136601866942237e-6 8.466231184459571e-7 8467/23451/5434/5440/9015/10514/2648/2074/9112/9219/9014/5931/5441/51082/5435/9013/4641/1108/8850/5928/2932/5437/57459/54815/2033/3066/3065/1107/57504/6908/60/53615/10919 33 Human_papillomavirus_type_18 R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 16/1364 33/10654 6.547760126462523e-7 2.1686181538843875e-6 9.594191680037718e-7 1147/351/4790/7316/5970/4792/4793/3146/10454/7189/6285/6233/7311/7334/3551/7314 16 Human_papillomavirus_type_18 R-HSA-68877 Mitotic Prometaphase 51/1364 200/10654 6.997585441093301e-7 2.311436467510074e-6 1.0226034715147544e-6 10844/115106/11130/22995/5903/22981/7531/1459/55869/1058/991/203068/51807/7532/1454/9212/1460/7277/6232/332/5885/891/5501/1457/983/3796/5519/699/7846/7283/3320/80097/8243/9126/10540/5527/701/7514/54930/5518/10383/55835/5347/84790/6396/9662/1453/8481/7280/5515/5516 51 Human_papillomavirus_type_18 R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 10/1364 14/10654 7.043376222801547e-7 2.320390787458759e-6 1.026564955550023e-6 6118/4436/9156/2956/4292/5111/5395/6119/6117/10714 10 Human_papillomavirus_type_18 R-HSA-73864 RNA Polymerase I Transcription 34/1364 112/10654 7.53446156118411e-7 2.4756087986747786e-6 1.0952350139064622e-6 5434/5440/902/9015/2648/2074/9112/9219/9014/5931/5441/51082/5435/4331/9013/1108/8850/5928/5437/57459/2965/54815/2068/3066/3065/2071/1107/2968/57504/6908/53615/1022/10919/5595 34 Human_papillomavirus_type_18 R-HSA-1989781 PPARA activates gene expression 35/1364 117/10654 7.664207965611238e-7 2.5115953280446325e-6 1.1111558278153217e-6 8841/79718/5468/9440/4802/6721/1543/6720/6837/9611/5469/2874/4800/9612/1024/6667/1387/6907/2033/9967/4801/6256/10498/183/2274/112950/10499/23054/9412/405/8202/8648/23097/10891/7296 35 Human_papillomavirus_type_18 R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 13/1364 23/10654 7.735629246987778e-7 2.521693313584992e-6 1.1156232813724603e-6 5434/5440/5430/5436/5441/5438/5431/5435/5433/5437/5439/51497/5432 13 Human_papillomavirus_type_18 R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 13/1364 23/10654 7.735629246987778e-7 2.521693313584992e-6 1.1156232813724603e-6 7321/6497/7316/9611/9612/4089/4088/142/3065/4087/6233/7311/7314 13 Human_papillomavirus_type_18 R-HSA-69186 Lagging Strand Synthesis 12/1364 20/10654 8.655747966252753e-7 2.814251040336628e-6 1.2450538546111705e-6 6118/1763/5982/5422/5111/6119/5985/5984/5983/6117/5981/10714 12 Human_papillomavirus_type_18 R-HSA-3214841 PKMTs methylate histone lysines 25/1364 71/10654 1.0637688673933368e-6 3.449610791912596e-6 1.5261435997782653e-6 55904/9070/11091/4790/9869/2146/8085/6839/5929/5931/79813/5970/29072/2122/84444/5928/56950/23512/80854/58508/9739/8726/64754/4297/10919 25 Human_papillomavirus_type_18 R-HSA-4085377 SUMOylation of SUMOylation proteins 16/1364 34/10654 1.0903965208583724e-6 3.5267512471512984e-6 1.5602713374124737e-6 5903/7175/9631/51588/6613/23636/10210/4927/9688/7341/23225/7329/9972/8021/6396/8480 16 Human_papillomavirus_type_18 R-HSA-9612973 Autophagy 35/1364 119/10654 1.1924726162719143e-6 3.846885686778487e-6 1.701902134501543e-6 5563/139341/1459/1915/8878/9821/51422/7249/1080/1460/10533/10013/53632/7316/1457/8678/6714/3043/5571/3320/128866/81631/10542/6233/3326/2475/7311/5562/7251/7431/3312/5564/11315/5565/7314 35 Human_papillomavirus_type_18 R-HSA-5689896 Ovarian tumor domain proteases 17/1364 38/10654 1.2251499484772229e-6 3.942062787587333e-6 1.7440094712438245e-6 7321/55611/7706/7316/983/2099/79589/7415/7128/5728/7157/7189/6233/7311/55593/78990/7314 17 Human_papillomavirus_type_18 R-HSA-913531 Interferon Signaling 50/1364 199/10654 1.438921723937447e-6 4.617934834962039e-6 2.043022276337134e-6 80263/3665/3837/3838/5903/7175/960/9631/2316/54739/23650/3383/23636/7706/9470/7316/103/6672/6772/8651/4927/9688/3659/6041/3840/1958/7341/6059/3717/23225/1973/3454/816/5371/51191/6233/5580/7311/81603/9972/5610/5300/8021/6396/7334/5696/8480/7314/5595/8554 50 Human_papillomavirus_type_18 R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 33/1364 110/10654 1.4679187523331169e-6 4.698853325767348e-6 2.0788214560984458e-6 1017/3725/1019/4790/1029/7321/5594/1027/1051/79813/3576/7316/890/6774/5970/1026/1031/5598/3552/1021/6195/8900/6233/2353/1030/51343/6196/7311/6197/3569/10919/7314/5595 33 Human_papillomavirus_type_18 R-HSA-8940973 RUNX2 regulates osteoblast differentiation 13/1364 24/10654 1.4900897092479746e-6 4.757561488138777e-6 2.104794556155981e-6 25/8841/23462/5594/5925/10013/4094/6714/23493/25937/367/860/5595 13 Human_papillomavirus_type_18 R-HSA-5693606 DNA Double Strand Break Response 26/1364 77/10654 1.6311269286947682e-6 5.1945119113818e-6 2.29810595621773e-6 8467/25/3838/10111/51588/51720/11200/472/7336/580/7316/9656/7341/10524/4683/7157/7329/8924/6233/672/7158/7311/79184/5599/7334/7314 26 Human_papillomavirus_type_18 R-HSA-5358508 Mismatch Repair 10/1364 15/10654 1.8696684443843928e-6 5.9087231753827375e-6 2.6140804284683354e-6 6118/4436/9156/2956/4292/5111/5395/6119/6117/10714 10 Human_papillomavirus_type_18 R-HSA-937039 IRAK1 recruits IKK complex 10/1364 15/10654 1.8696684443843928e-6 5.9087231753827375e-6 2.6140804284683354e-6 1147/7316/57162/7189/6233/7311/7334/3551/57161/7314 10 Human_papillomavirus_type_18 R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 10/1364 15/10654 1.8696684443843928e-6 5.9087231753827375e-6 2.6140804284683354e-6 1147/7316/57162/7189/6233/7311/7334/3551/57161/7314 10 Human_papillomavirus_type_18 R-HSA-73933 Resolution of Abasic Sites (AP sites) 17/1364 39/10654 1.914256647953811e-6 6.03428110852445e-6 2.6696285605981553e-6 6118/328/4913/7515/5982/6996/5111/6119/5985/142/5984/4595/4968/5983/6117/5981/10714 17 Human_papillomavirus_type_18 R-HSA-111471 Apoptotic factor-mediated response 11/1364 18/10654 1.959448570816189e-6 6.1300632870370444e-006 2.712003589993506e-6 1029/842/5594/54205/836/708/331/581/317/578/5595 11 Human_papillomavirus_type_18 R-HSA-1368082 RORA activates gene expression 11/1364 18/10654 1.959448570816189e-6 6.1300632870370444e-006 2.712003589993506e-6 79718/6720/5469/1387/6907/2033/6256/10498/10499/23054/8648 11 Human_papillomavirus_type_18 R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 11/1364 18/10654 1.959448570816189e-6 6.1300632870370444e-006 2.712003589993506e-6 4893/5594/5598/6195/1385/6196/1956/6197/3845/3265/5595 11 Human_papillomavirus_type_18 R-HSA-3214847 HATs acetylate histones 39/1364 142/10654 2.0130586873331694e-6 6.2819570092155686e-6 2.7792029483943782e-6 9643/23774/8295/8464/55167/11091/64769/84148/7862/2648/10474/51147/6871/5931/284058/117143/10629/86/84289/11143/10933/27097/8850/10524/1387/27154/2033/7994/6881/10499/57634/1386/6880/60/10902/6883/51230/9913/8648 39 Human_papillomavirus_type_18 R-HSA-2871796 FCERI mediated MAPK activation 15/1364 32/10654 2.5255457751858894e-6 7.861473315240288e-6 3.47799734770356e-6 3725/5601/4893/5336/5594/4214/6850/4067/5602/5609/2353/3845/5599/3265/5595 15 Human_papillomavirus_type_18 R-HSA-383280 Nuclear Receptor transcription pathway 20/1364 52/10654 2.6225089539668645e-6 8.122583842460963e-6 3.593515353644057e-6 7068/5241/5468/3172/5915/6097/2100/9611/5469/9612/8856/2099/7101/2908/3164/6256/367/5914/8431/7421 20 Human_papillomavirus_type_18 R-HSA-72165 mRNA Splicing - Minor Pathway 20/1364 52/10654 2.6225089539668645e-6 8.122583842460963e-6 3.593515353644057e-6 23451/5434/5440/6431/24148/5430/85437/4904/5436/5441/5438/5431/5435/5433/5437/5439/6634/6426/5432/10992 20 Human_papillomavirus_type_18 R-HSA-177243 Interactions of Rev with host cellular proteins 16/1364 36/10654 2.8108146683712335e-6 8.684158751535004e-6 3.841961919062016e-6 3837/5903/7175/9631/4869/23636/4927/9688/23225/5901/7514/9972/8021/6396/1104/8480 16 Human_papillomavirus_type_18 R-HSA-5675221 Negative regulation of MAPK pathway 17/1364 40/10654 2.934465928255342e-6 9.043689039437059e-6 4.00102184811098e-6 4893/1844/5594/7316/5519/6233/5527/7311/5518/3845/3265/369/7529/7314/5595/5515/5516 17 Human_papillomavirus_type_18 R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 12/1364 22/10654 3.4681654045022185e-6 1.0635707240473472e-5 4.7053472154649986e-6 4000/3725/351/2309/10018/7531/823/995/6648/8851/5052/1020 12 Human_papillomavirus_type_18 R-HSA-8863678 Neurodegenerative Diseases 12/1364 22/10654 3.4681654045022185e-6 1.0635707240473472e-5 4.7053472154649986e-6 4000/3725/351/2309/10018/7531/823/995/6648/8851/5052/1020 12 Human_papillomavirus_type_18 R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 14/1364 29/10654 3.5383769366289737e-6 1.0824295948997993e-5 4.78878081649034e-6 5434/5440/5430/5436/5441/5438/5431/5435/5433/5437/3320/5439/9271/5432 14 Human_papillomavirus_type_18 R-HSA-171007 p38MAPK events 9/1364 13/10654 3.972424060653632e-6 1.2122237551183812e-5 5.363003645832655e-6 4893/6714/5898/1432/5603/3845/5600/3265/6300 9 Human_papillomavirus_type_18 R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 15/1364 33/10654 4.084520577302262e-6 1.240336077508413e-5 5.4873754763911485e-6 3303/5903/7175/9631/23636/4927/9688/23225/5901/7514/9972/8021/6396/3304/8480 15 Human_papillomavirus_type_18 R-HSA-180746 Nuclear import of Rev protein 15/1364 33/10654 4.084520577302262e-6 1.240336077508413e-5 5.4873754763911485e-6 3837/5903/7175/9631/4869/23636/4927/9688/23225/5901/9972/8021/6396/1104/8480 15 Human_papillomavirus_type_18 R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 11/1364 19/10654 4.114751881643062e-6 1.2434359700731589e-5 5.501089722673015e-6 4893/5290/7316/1950/3320/6233/7311/1956/3845/3265/7314 11 Human_papillomavirus_type_18 R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 11/1364 19/10654 4.114751881643062e-6 1.2434359700731589e-5 5.501089722673015e-6 4893/5290/7316/1950/3320/6233/7311/1956/3845/3265/7314 11 Human_papillomavirus_type_18 R-HSA-390466 Chaperonin-mediated protein folding 29/1364 95/10654 4.273711406456229e-6 1.2883372734996692e-5 5.699737746985569e-6 10694/9134/8841/1459/51807/8237/10575/898/1460/7277/7203/10576/908/6774/1457/26272/6950/7846/55294/2783/10238/7157/10574/10383/60/84790/22948/10693/7280 29 Human_papillomavirus_type_18 R-HSA-5693565 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 25/1364 76/10654 4.4120840556212385e-6 1.3204774478435666e-5 5.841929212427679e-6 8467/25/10111/51588/51720/11200/472/7336/580/7316/9656/7341/10524/4683/7157/7329/8924/6233/672/7158/7311/79184/5599/7334/7314 25 Human_papillomavirus_type_18 R-HSA-1295596 Spry regulation of FGF signaling 10/1364 16/10654 4.412223356321096e-6 1.3204774478435666e-5 5.841929212427679e-6 5594/7316/6714/6233/7311/5518/7314/5595/5515/5516 10 Human_papillomavirus_type_18 R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 10/1364 16/10654 4.412223356321096e-6 1.3204774478435666e-5 5.841929212427679e-6 1147/8945/4790/6500/7316/23291/6233/7311/3551/7314 10 Human_papillomavirus_type_18 R-HSA-73887 Death Receptor Signalling 38/1364 141/10654 4.448021897315746e-6 1.327991152996672e-5 5.875170623478795e-6 7124/1147/4804/8841/4790/10018/7531/29/8793/8878/1894/355/841/27005/7316/9828/5970/4792/8797/7128/843/836/10616/8837/10454/3066/3065/7189/6233/7311/26574/331/5599/1540/3551/8795/5663/7314 38 Human_papillomavirus_type_18 R-HSA-211000 Gene Silencing by RNA 37/1364 136/10654 4.661376854736675e-6 1.3883525308352399e-5 6.142215620781382e-6 27161/5434/5440/5903/7175/9631/5430/5436/57690/27327/5441/23636/192670/5438/5431/5435/54487/5433/4927/9688/5437/23225/3320/5439/192669/5901/23112/29102/9972/8021/7257/6396/26523/9271/5432/23405/8480 37 Human_papillomavirus_type_18 R-HSA-2173788 Downregulation of TGF-beta receptor signaling 13/1364 26/10654 4.8408652998452695e-6 1.4383623689970872e-5 6.363464332710226e-6 57154/10273/7316/5501/4092/4088/9958/4087/5499/6233/7514/7311/7314 13 Human_papillomavirus_type_18 R-HSA-2219528 PI3K/AKT Signaling in Cancer 30/1364 101/10654 5.4533232530958675e-6 1.616474338984503e-5 7.15145016484372e-6 1147/5290/2309/842/3815/207/4303/1027/7249/2064/2100/1950/4233/1026/6714/2099/2932/5159/2247/3164/10000/5728/2264/2066/208/2475/1385/1956/5156/4193 30 Human_papillomavirus_type_18 R-HSA-1227986 Signaling by ERBB2 19/1364 50/10654 5.740296852112504e-6 1.697487783410412e-5 7.509862047124629e-6 4893/5290/10273/207/2064/7316/1950/6714/10000/3320/2066/208/6233/5580/7311/1956/3845/3265/7314 19 Human_papillomavirus_type_18 R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 56/1364 244/10654 7.144895554406995e-6 2.1078290447918023e-5 9.32525435529554e-6 23451/5434/5440/5903/6431/6627/7175/24148/9631/5430/85437/4904/5436/55749/3178/5441/23636/5438/5431/9092/5093/81608/5435/5433/10713/1655/3185/3190/24144/4927/9688/22938/5437/4670/23225/10189/10949/3181/5439/1660/3191/6638/9877/3187/9972/6634/8021/3192/6396/3312/6426/5432/8480/10992/55339/1994 56 Human_papillomavirus_type_18 R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF) 20/1364 55/10654 7.182925178280224e-6 2.114026794176312e-5 9.352673841512289e-6 3837/79718/4802/6721/3638/6720/5469/4800/6667/1387/6907/1717/4801/5901/6256/10498/9871/10499/23054/8648 20 Human_papillomavirus_type_18 R-HSA-442755 Activation of NMDA receptors and postsynaptic events 28/1364 93/10654 8.358359160236757e-6 2.4541565193886648e-5 1.0857443030094782e-5 5563/3838/4893/2904/51807/5594/51422/7277/53632/6714/5571/7846/6195/816/2066/1385/6196/5562/10383/84790/8536/6197/3845/3265/5564/5565/7280/5595 28 Human_papillomavirus_type_18 R-HSA-5655253 Signaling by FGFR2 in disease 17/1364 43/10654 9.542619390890444e-6 2.7952672838410214e-5 1.236655243804571e-5 5434/5440/4893/5290/5430/5436/5441/5438/5431/5435/5433/5437/2247/5439/3845/3265/5432 17 Human_papillomavirus_type_18 R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 9/1364 14/10654 9.854979649725972e-6 2.8799728764610958e-5 1.2741298766952219e-5 6118/4436/9156/4292/5111/5395/6119/6117/10714 9 Human_papillomavirus_type_18 R-HSA-3214815 HDACs deacetylate histones 28/1364 94/10654 1.0472113759376123e-5 3.053137391818109e-5 1.3507396546563716e-5 8841/79718/23186/55869/5978/9112/9219/5931/8819/83933/9611/2874/9612/1108/64426/79685/5928/57459/6907/54815/3066/3065/1107/23028/57504/51317/10284/53615 28 Human_papillomavirus_type_18 R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 12/1364 24/10654 1.1325373782963952e-5 3.2788145077951583e-005 1.4505815518849671e-5 6118/1763/5982/5422/5111/6119/5985/5984/5983/6117/5981/10714 12 Human_papillomavirus_type_18 R-HSA-452723 Transcriptional regulation of pluripotent stem cells 12/1364 24/10654 1.1325373782963952e-5 3.2788145077951583e-005 1.4505815518849671e-5 7547/6657/27086/5460/6774/57167/4089/9314/5087/79923/2247/4087 12 Human_papillomavirus_type_18 R-HSA-933542 TRAF6 mediated NF-kB activation 12/1364 24/10654 1.1325373782963952e-5 3.2788145077951583e-005 1.4505815518849671e-5 1147/351/4790/4214/7706/5970/4792/4793/3146/7189/6285/3551 12 Human_papillomavirus_type_18 R-HSA-165159 mTOR signalling 16/1364 40/10654 1.462373323853492e-5 4.223878298200086e-5 1.8686875766255153e-5 5563/6194/207/51422/7249/53632/6198/5571/6794/208/10542/2475/5562/5564/5565/7529 16 Human_papillomavirus_type_18 R-HSA-5673000 RAF activation 14/1364 32/10654 1.479179047746737e-5 4.262506675873428e-5 1.885777171629739e-5 4893/6714/5519/3717/816/5527/5518/3845/3265/369/5245/7529/5515/5516 14 Human_papillomavirus_type_18 R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 11/1364 21/10654 1.5017858436257957e-5 4.317634300424163e-5 1.9101662046117576e-5 6118/328/5982/5111/6119/5985/5984/5983/6117/5981/10714 11 Human_papillomavirus_type_18 R-HSA-391251 Protein folding 29/1364 101/10654 1.6052842210557305e-5 4.604533493189878e-5 2.0370933837148204e-5 10694/9134/8841/1459/51807/8237/10575/898/1460/7277/7203/10576/908/6774/1457/26272/6950/7846/55294/2783/10238/7157/10574/10383/60/84790/22948/10693/7280 29 Human_papillomavirus_type_18 R-HSA-5675482 Regulation of necroptotic cell death 10/1364 18/10654 1.8889881372850708e-5 5.4058139781291654e-5 2.3915881825437958e-5 355/841/7316/8797/8837/6233/7311/331/8795/7314 10 Human_papillomavirus_type_18 R-HSA-5654743 Signaling by FGFR4 16/1364 41/10654 2.115474516373856e-5 6.04004448123294e-5 2.672178336472239e-5 4893/5290/5594/7316/6714/2247/2264/6233/7311/5518/3845/3265/7314/5595/5515/5516 16 Human_papillomavirus_type_18 R-HSA-186763 Downstream signal transduction 13/1364 29/10654 2.1762625971794093e-5 6.0935998877552746e-5 2.69587180388868e-5 4893/5290/6778/6776/6774/6772/6714/5159/1398/3845/6777/3265/5156 13 Human_papillomavirus_type_18 R-HSA-8863795 Downregulation of ERBB2 signaling 13/1364 29/10654 2.1762625971794093e-5 6.0935998877552746e-5 2.69587180388868e-5 10273/207/2064/7316/1950/10000/3320/2066/208/6233/7311/1956/7314 13 Human_papillomavirus_type_18 R-HSA-9619483 Activation of AMPK downstream of NMDARs 13/1364 29/10654 2.1762625971794093e-5 6.0935998877552746e-5 2.69587180388868e-5 5563/51807/51422/7277/53632/5571/7846/5562/10383/84790/5564/5565/7280 13 Human_papillomavirus_type_18 R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 9/1364 15/10654 2.1832946457738304e-5 6.0935998877552746e-5 2.69587180388868e-5 1499/1452/5519/2932/8312/5527/5518/5515/5516 9 Human_papillomavirus_type_18 R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 9/1364 15/10654 2.1832946457738304e-5 6.0935998877552746e-5 2.69587180388868e-5 1499/1452/5519/2932/8312/5527/5518/5515/5516 9 Human_papillomavirus_type_18 R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 9/1364 15/10654 2.1832946457738304e-5 6.0935998877552746e-5 2.69587180388868e-5 1499/1452/5519/2932/8312/5527/5518/5515/5516 9 Human_papillomavirus_type_18 R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 9/1364 15/10654 2.1832946457738304e-5 6.0935998877552746e-5 2.69587180388868e-5 1499/1452/5519/2932/8312/5527/5518/5515/5516 9 Human_papillomavirus_type_18 R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 9/1364 15/10654 2.1832946457738304e-5 6.0935998877552746e-5 2.69587180388868e-5 1499/1452/5519/2932/8312/5527/5518/5515/5516 9 Human_papillomavirus_type_18 R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 9/1364 15/10654 2.1832946457738304e-5 6.0935998877552746e-5 2.69587180388868e-5 1499/1452/5519/2932/8312/5527/5518/5515/5516 9 Human_papillomavirus_type_18 R-HSA-8866910 TFAP2 (AP-2) family regulates transcription of growth factors and their receptors 9/1364 15/10654 2.1832946457738304e-5 6.0935998877552746e-5 2.69587180388868e-5 7020/7021/3815/7422/2064/2099/7022/1956/7528 9 Human_papillomavirus_type_18 R-HSA-8854518 AURKA Activation by TPX2 23/1364 73/10654 2.3374927086995162e-5 6.50934068207354e-5 2.8797998440905063e-5 115106/22995/22981/7531/203068/7532/1454/22974/7277/983/6790/7846/7283/3320/10540/54930/5518/10383/55835/5347/9662/1453/8481 23 Human_papillomavirus_type_18 R-HSA-1912408 Pre-NOTCH Transcription and Translation 27/1364 93/10654 2.5054965234664848e-5 6.96158094439681e-5 3.0798756275744854e-5 27161/3725/2648/7027/55534/57690/27327/84441/51548/10046/192670/1869/4854/22938/8850/1387/2033/4855/595/192669/7157/23112/9794/4343/26523/3516/4851 27 Human_papillomavirus_type_18 R-HSA-113510 E2F mediated regulation of DNA replication 11/1364 22/10654 2.656755146801379e-5 7.365379223944894e-5 3.258520175353195e-5 7027/5925/5422/1869/891/983/84515/5519/5518/5515/5516 11 Human_papillomavirus_type_18 R-HSA-2426168 Activation of gene expression by SREBF (SREBP) 16/1364 42/10654 3.0145543259570013e-5 8.338700384941194e-5 3.68912755397856e-5 79718/4802/6721/6720/5469/4800/6667/1387/6907/1717/4801/6256/10498/10499/23054/8648 16 Human_papillomavirus_type_18 R-HSA-110373 Resolution of AP sites via the multiple-nucleotide patch replacement pathway 12/1364 26/10654 3.159957266328314e-5 8.721482055066146e-5 3.858474135727205e-5 6118/328/5982/5111/6119/5985/142/5984/5983/6117/5981/10714 12 Human_papillomavirus_type_18 R-HSA-180786 Extension of Telomeres 13/1364 30/10654 3.392678880737942e-5 9.3134943633316e-5 4.120386522297732e-5 6118/7015/1763/5982/5422/5111/6119/5985/5984/5983/6117/5981/10714 13 Human_papillomavirus_type_18 R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 13/1364 30/10654 3.392678880737942e-5 9.3134943633316e-5 4.120386522297732e-5 7124/1147/27005/7316/7128/10616/10454/6233/7311/331/1540/3551/7314 13 Human_papillomavirus_type_18 R-HSA-165054 Rev-mediated nuclear export of HIV RNA 14/1364 34/10654 3.404449630396575e-5 9.3134943633316e-5 4.120386522297732e-5 5903/7175/9631/23636/4927/9688/23225/5901/7514/9972/8021/6396/1104/8480 14 Human_papillomavirus_type_18 R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 14/1364 34/10654 3.404449630396575e-5 9.3134943633316e-5 4.120386522297732e-5 7321/7706/7316/3093/7128/54941/83737/51191/6233/7311/55593/5300/1540/7314 14 Human_papillomavirus_type_18 R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 10/1364 19/10654 3.530669191863695e-5 9.63756293691145e-5 4.2637578210592224e-5 7027/7153/5934/1869/5933/5111/4609/5928/1874/3065 10 Human_papillomavirus_type_18 R-HSA-2980766 Nuclear Envelope Breakdown 18/1364 52/10654 4.4124730435087394e-5 1.1968393380990311e-4 5.2949413889964765e-5 4000/5903/7175/9631/23636/7443/891/983/4927/9688/23225/7444/9972/5347/8021/6396/7112/8480 18 Human_papillomavirus_type_18 R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 9/1364 16/10654 4.423101901670332e-5 1.1968393380990311e-4 5.2949413889964765e-5 7027/5934/1869/890/983/5933/5928/1874/3065 9 Human_papillomavirus_type_18 R-HSA-205043 NRIF signals cell death from the nucleus 9/1364 16/10654 4.423101901670332e-5 1.1968393380990311e-4 5.2949413889964765e-5 4804/8878/7316/7189/6233/7311/5599/5663/7314 9 Human_papillomavirus_type_18 R-HSA-2559584 Formation of Senescence-Associated Heterochromatin Foci (SAHF) 9/1364 16/10654 4.423101901670332e-5 1.1968393380990311e-4 5.2949413889964765e-5 3159/7290/5925/29855/25842/7157/8091/57634/23523 9 Human_papillomavirus_type_18 R-HSA-72163 mRNA Splicing - Major Pathway 43/1364 183/10654 4.47778693355579e-5 1.2090024720600634e-4 5.3487523554144684e-5 23451/5434/5440/6431/6627/24148/5430/4904/5436/55749/3178/5441/5438/5431/9092/5093/81608/5435/5433/10713/1655/3185/3190/24144/22938/5437/4670/10189/10949/3181/5439/1660/3191/6638/3187/6634/3192/3312/6426/5432/10992/55339/1994 43 Human_papillomavirus_type_18 R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 11/1364 23/10654 4.5047386213095824e-5 1.2136410775849244e-4 5.3692740274542804e-5 5601/7316/5602/10454/7189/5609/6233/7311/5599/7334/7314 11 Human_papillomavirus_type_18 R-HSA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 8/1364 13/10654 5.013486803065241e-5 1.3390861525606514e-4 5.9242560525185186e-5 7027/5925/5422/1869/5519/5518/5515/5516 8 Human_papillomavirus_type_18 R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 8/1364 13/10654 5.013486803065241e-5 1.3390861525606514e-4 5.9242560525185186e-5 207/2064/7316/10000/208/6233/7311/7314 8 Human_papillomavirus_type_18 R-HSA-202670 ERKs are inactivated 8/1364 13/10654 5.013486803065241e-5 1.3390861525606514e-4 5.9242560525185186e-5 5594/5519/5598/5518/51231/5595/5515/5516 8 Human_papillomavirus_type_18 R-HSA-209543 p75NTR recruits signalling complexes 8/1364 13/10654 5.013486803065241e-5 1.3390861525606514e-4 5.9242560525185186e-5 4804/8878/7316/7189/6233/7311/3551/7314 8 Human_papillomavirus_type_18 R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 13/1364 31/10654 5.16223024203283e-5 1.3729100558040202e-4 6.073896509277893e-5 5903/7175/9631/23636/4927/9688/23225/5901/7514/9972/8021/6396/8480 13 Human_papillomavirus_type_18 R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 13/1364 31/10654 5.16223024203283e-5 1.3729100558040202e-4 6.073896509277893e-5 857/1499/1856/1452/5519/2932/1455/8312/5527/1855/5518/5515/5516 13 Human_papillomavirus_type_18 R-HSA-72172 mRNA Splicing 44/1364 191/10654 6.075855160433626e-5 1.6124384848843084e-4 7.133595127634622e-5 23451/5434/5440/6431/6627/24148/5430/85437/4904/5436/55749/3178/5441/5438/5431/9092/5093/81608/5435/5433/10713/1655/3185/3190/24144/22938/5437/4670/10189/10949/3181/5439/1660/3191/6638/3187/6634/3192/3312/6426/5432/10992/55339/1994 44 Human_papillomavirus_type_18 R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 10/1364 20/10654 6.252741551838673e-5 1.645318857496532e-4 7.279061307002202e-5 1147/7321/7098/7316/7189/6233/7311/7334/3551/7314 10 Human_papillomavirus_type_18 R-HSA-5213460 RIPK1-mediated regulated necrosis 10/1364 20/10654 6.252741551838673e-5 1.645318857496532e-4 7.279061307002202e-5 355/841/7316/8797/8837/6233/7311/331/8795/7314 10 Human_papillomavirus_type_18 R-HSA-5218859 Regulated Necrosis 10/1364 20/10654 6.252741551838673e-5 1.645318857496532e-4 7.279061307002202e-5 355/841/7316/8797/8837/6233/7311/331/8795/7314 10 Human_papillomavirus_type_18 R-HSA-622312 Inflammasomes 10/1364 20/10654 6.252741551838673e-5 1.645318857496532e-4 7.279061307002202e-5 834/596/351/4790/58484/7295/5970/598/10628/3326 10 Human_papillomavirus_type_18 R-HSA-168276 NS1 Mediated Effects on Host Pathways 15/1364 40/10654 6.601006427938936e-5 1.7296307982067846e-4 7.652066079023151e-5 3837/3838/5903/7175/9631/23636/4927/9688/3840/23225/9972/5610/8021/6396/8480 15 Human_papillomavirus_type_18 R-HSA-5654741 Signaling by FGFR3 15/1364 40/10654 6.601006427938936e-5 1.7296307982067846e-4 7.652066079023151e-5 4893/5290/5594/7316/6714/2247/6233/7311/5518/3845/3265/7314/5595/5515/5516 15 Human_papillomavirus_type_18 R-HSA-69190 DNA strand elongation 13/1364 32/10654 7.682212638123271e-5 2.0086964413787585e-4 8.886681434017392e-5 6118/1763/5982/5422/84515/5111/6119/5985/5984/5983/6117/5981/10714 13 Human_papillomavirus_type_18 R-HSA-196299 Beta-catenin phosphorylation cascade 9/1364 17/10654 8.332131936730894e-5 2.1740562742478508e-4 9.61825048866326e-5 1499/1452/5519/2932/8312/5527/5518/5515/5516 9 Human_papillomavirus_type_18 R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 26/1364 94/10654 8.692885456904914e-5 2.2634305529299587e-4 1.0013651569026515e-4 10844/115106/22995/22981/7531/203068/51807/7532/1454/7277/983/7846/7283/3320/80097/10540/54930/5518/10383/55835/5347/84790/9662/1453/8481/7280 26 Human_papillomavirus_type_18 R-HSA-5250941 Negative epigenetic regulation of rRNA expression 29/1364 110/10654 9.021668720654039e-5 2.3441239646552963e-4 1.037064759344067e-4 8467/5434/5440/902/9015/1786/6839/9014/5441/51082/5435/8819/4331/9013/23309/64426/79685/5437/2965/2068/3066/3065/2071/2968/6908/23411/25942/10284/1022 29 Human_papillomavirus_type_18 R-HSA-174411 Polymerase switching on the C-strand of the telomere 8/1364 14/10654 1.0384138587188753e-4 2.637443788402542e-4 1.1668324921994466e-4 5982/5422/5111/5985/5984/5983/5981/10714 8 Human_papillomavirus_type_18 R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 8/1364 14/10654 1.0384138587188753e-4 2.637443788402542e-4 1.1668324921994466e-4 1452/5519/2932/8312/5527/5518/5515/5516 8 Human_papillomavirus_type_18 R-HSA-4839744 truncated APC mutants destabilize the destruction complex 8/1364 14/10654 1.0384138587188753e-4 2.637443788402542e-4 1.1668324921994466e-4 1452/5519/2932/8312/5527/5518/5515/5516 8 Human_papillomavirus_type_18 R-HSA-4839748 AMER1 mutants destabilize the destruction complex 8/1364 14/10654 1.0384138587188753e-4 2.637443788402542e-4 1.1668324921994466e-4 1452/5519/2932/8312/5527/5518/5515/5516 8 Human_papillomavirus_type_18 R-HSA-5467337 APC truncation mutants have impaired AXIN binding 8/1364 14/10654 1.0384138587188753e-4 2.637443788402542e-4 1.1668324921994466e-4 1452/5519/2932/8312/5527/5518/5515/5516 8 Human_papillomavirus_type_18 R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 8/1364 14/10654 1.0384138587188753e-4 2.637443788402542e-4 1.1668324921994466e-4 1452/5519/2932/8312/5527/5518/5515/5516 8 Human_papillomavirus_type_18 R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 8/1364 14/10654 1.0384138587188753e-4 2.637443788402542e-4 1.1668324921994466e-4 1452/5519/2932/8312/5527/5518/5515/5516 8 Human_papillomavirus_type_18 R-HSA-69091 Polymerase switching 8/1364 14/10654 1.0384138587188753e-4 2.637443788402542e-4 1.1668324921994466e-4 5982/5422/5111/5985/5984/5983/5981/10714 8 Human_papillomavirus_type_18 R-HSA-69109 Leading Strand Synthesis 8/1364 14/10654 1.0384138587188753e-4 2.637443788402542e-4 1.1668324921994466e-4 5982/5422/5111/5985/5984/5983/5981/10714 8 Human_papillomavirus_type_18 R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 8/1364 14/10654 1.0384138587188753e-4 2.637443788402542e-4 1.1668324921994466e-4 8841/79718/9611/2874/9612/6907/3065/25942 8 Human_papillomavirus_type_18 R-HSA-9005895 Pervasive developmental disorders 8/1364 14/10654 1.0384138587188753e-4 2.637443788402542e-4 1.1668324921994466e-4 8841/79718/9611/2874/9612/6907/3065/25942 8 Human_papillomavirus_type_18 R-HSA-1632852 Macroautophagy 26/1364 95/10654 1.0535573878755679e-4 2.670445460696848e-4 1.1814327743738915e-4 5563/139341/1459/8878/9821/51422/7249/1460/10533/53632/7316/1457/8678/6714/5571/128866/81631/10542/6233/2475/7311/5562/3312/5564/5565/7314 26 Human_papillomavirus_type_18 R-HSA-389513 CTLA4 inhibitory signaling 10/1364 21/10654 1.0571792195668538e-4 2.6741682091691087e-4 1.1830797569169208e-4 207/6714/5519/4067/10000/208/5527/5518/5515/5516 10 Human_papillomavirus_type_18 R-HSA-1839126 FGFR2 mutant receptor activation 13/1364 33/10654 1.1201362597702274e-4 2.821925425222358e-4 1.248449082096848e-4 5434/5440/5430/5436/5441/5438/5431/5435/5433/5437/2247/5439/5432 13 Human_papillomavirus_type_18 R-HSA-5357905 Regulation of TNFR1 signaling 13/1364 33/10654 1.1201362597702274e-4 2.821925425222358e-4 1.248449082096848e-4 7124/1147/841/27005/7316/7128/10616/6233/7311/331/1540/3551/7314 13 Human_papillomavirus_type_18 R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 7/1364 11/10654 1.145527735173472e-4 2.86843840138196e-4 1.2690269052643302e-4 7422/3091/10370/1387/2033/405/768 7 Human_papillomavirus_type_18 R-HSA-4755510 SUMOylation of immune response proteins 7/1364 11/10654 1.145527735173472e-4 2.86843840138196e-4 1.2690269052643302e-4 51588/10210/5970/4792/7341/7329/6612 7 Human_papillomavirus_type_18 R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 7/1364 11/10654 1.145527735173472e-4 2.86843840138196e-4 1.2690269052643302e-4 7098/7316/10454/7189/6233/7311/7314 7 Human_papillomavirus_type_18 R-HSA-380259 Loss of Nlp from mitotic centrosomes 21/1364 70/10654 1.1601429958367856e-4 2.8933686763640316e-4 1.2800563175371002e-4 115106/22995/22981/7531/203068/7532/1454/7277/983/7846/7283/3320/10540/54930/5518/10383/55835/5347/9662/1453/8481 21 Human_papillomavirus_type_18 R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 21/1364 70/10654 1.1601429958367856e-4 2.8933686763640316e-4 1.2800563175371002e-4 115106/22995/22981/7531/203068/7532/1454/7277/983/7846/7283/3320/10540/54930/5518/10383/55835/5347/9662/1453/8481 21 Human_papillomavirus_type_18 R-HSA-1643713 Signaling by EGFR in Cancer 11/1364 25/10654 1.162708227070319e-4 2.893955146335343e-4 1.2803157779363075e-4 4893/5290/7316/1950/3320/6233/7311/1956/3845/3265/7314 11 Human_papillomavirus_type_18 R-HSA-168253 Host Interactions with Influenza Factors 15/1364 42/10654 1.2618957174461546e-4 3.134548962136248e-4 1.3867569779092478e-4 3837/3838/5903/7175/9631/23636/4927/9688/3840/23225/9972/5610/8021/6396/8480 15 Human_papillomavirus_type_18 R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 14/1364 38/10654 1.4386730979695127e-4 3.5665309135292107e-4 1.5778702744827935e-4 6627/27250/5908/3313/6175/3185/5898/6950/3181/998/6648/302/4282/5721 14 Human_papillomavirus_type_18 R-HSA-187687 Signalling to ERKs 13/1364 34/10654 1.6028023006034448e-4 3.965498919022865e-4 1.754377858911718e-4 4893/5594/6714/5898/1432/5603/1398/3845/5600/3265/6300/7529/5595 13 Human_papillomavirus_type_18 R-HSA-195258 RHO GTPase Effectors 65/1364 327/10654 1.6390565122390623e-4 4.0471335749521183e-4 1.790493877553187e-4 11130/25/5590/5903/4638/1499/7531/5747/1058/4659/991/1856/4627/51807/2316/7532/10971/4771/9212/5594/1027/1080/7533/2810/7277/6232/7534/332/5501/10398/6279/6714/3796/5519/1432/4637/699/7846/999/995/998/4628/23028/5527/1855/5580/701/7514/367/8826/10499/5518/10383/5347/60/5300/84790/6396/5600/7280/7529/4221/5595/5515/5516 65 Human_papillomavirus_type_18 R-HSA-1433557 Signaling by SCF-KIT 15/1364 43/10654 1.7110111910964408e-4 4.2164204352019435e-4 1.865388140669052e-4 4893/5290/3815/4318/6776/6774/6772/6714/8651/4067/3717/1111/3845/6777/3265 15 Human_papillomavirus_type_18 R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 23/1364 82/10654 1.7369968967161138e-4 4.2635378373940977e-4 1.8862333681835062e-4 10844/115106/22995/22981/7531/203068/7532/1454/7277/983/7846/7283/3320/80097/10540/54930/5518/10383/55835/5347/9662/1453/8481 23 Human_papillomavirus_type_18 R-HSA-380287 Centrosome maturation 23/1364 82/10654 1.7369968967161138e-4 4.2635378373940977e-4 1.8862333681835062e-4 10844/115106/22995/22981/7531/203068/7532/1454/7277/983/7846/7283/3320/80097/10540/54930/5518/10383/55835/5347/9662/1453/8481 23 Human_papillomavirus_type_18 R-HSA-1912422 Pre-NOTCH Expression and Processing 28/1364 109/10654 1.9165580025908404e-4 4.6950000773527095e-4 2.0771167390271333e-4 27161/3725/2648/7027/55534/57690/27327/84441/51548/10046/192670/488/1869/4854/22938/8850/1387/2033/4855/595/192669/7157/23112/9794/4343/26523/3516/4851 28 Human_papillomavirus_type_18 R-HSA-2500257 Resolution of Sister Chromatid Cohesion 31/1364 126/10654 2.085865985224043e-4 5.099695971748546e-4 2.2561584009261302e-4 11130/5903/55869/1058/991/51807/9212/7277/6232/332/5885/891/5501/983/3796/5519/699/7846/8243/9126/5527/701/7514/5518/10383/5347/84790/6396/7280/5515/5516 31 Human_papillomavirus_type_18 R-HSA-4420097 VEGFA-VEGFR2 Pathway 26/1364 99/10654 2.1888331356451228e-4 5.340924861436626e-4 2.3628805641748616e-4 5590/4893/857/5290/1499/5747/207/7422/3315/6714/1432/10000/3320/4846/5603/998/208/1398/5580/2475/3791/60/3845/5600/3265/6300 26 Human_papillomavirus_type_18 R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 13/1364 35/10654 2.2538478069569008e-4 5.488782306353864e-4 2.4282942316439671e-4 5903/7175/9631/23636/891/983/4927/9688/23225/9972/8021/6396/8480 13 Human_papillomavirus_type_18 R-HSA-2197563 NOTCH2 intracellular domain regulates transcription 7/1364 12/10654 2.445085621574883e-4 5.919680978549716e-4 2.618928274263033e-4 55534/84441/10046/2033/9794/1385/3516 7 Human_papillomavirus_type_18 R-HSA-5689877 Josephin domain DUBs 7/1364 12/10654 2.445085621574883e-4 5.919680978549716e-4 2.618928274263033e-4 4287/7316/7415/6233/7311/5886/7314 7 Human_papillomavirus_type_18 R-HSA-8866907 Activation of the TFAP2 (AP-2) family of transcription factors 7/1364 12/10654 2.445085621574883e-4 5.919680978549716e-4 2.618928274263033e-4 7020/7021/51741/10370/1387/2033/7022 7 Human_papillomavirus_type_18 R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 12/1364 31/10654 2.496235819593007e-4 6.020048326086437e-4 2.6633318300001016e-4 3837/5903/7175/9631/23636/4927/9688/23225/9972/8021/6396/8480 12 Human_papillomavirus_type_18 R-HSA-5654733 Negative regulation of FGFR4 signaling 12/1364 31/10654 2.496235819593007e-4 6.020048326086437e-4 2.6633318300001016e-4 5594/7316/6714/2247/2264/6233/7311/5518/7314/5595/5515/5516 12 Human_papillomavirus_type_18 R-HSA-1368108 BMAL1:CLOCK,NPAS2 activates circadian gene expression 11/1364 27/10654 2.664178931147544e-4 6.412616729622576e-4 2.837008164135083e-4 79718/5469/8553/1387/6907/6256/10498/10499/23054/8648/5054 11 Human_papillomavirus_type_18 R-HSA-5693571 Nonhomologous End-Joining (NHEJ) 20/1364 69/10654 2.7998484825380297e-4 6.726135039288652e-4 2.9757119166952086e-4 10111/51588/7520/51720/472/7336/580/5591/64421/9656/22976/7341/10524/4683/8924/672/7158/79184/7334/2547 20 Human_papillomavirus_type_18 R-HSA-5578749 Transcriptional regulation by small RNAs 27/1364 106/10654 2.873276219699988e-4 6.889206688933176e-4 3.047856506164182e-4 27161/5434/5440/5903/7175/9631/5430/5436/27327/5441/23636/5438/5431/5435/5433/4927/9688/5437/23225/5439/5901/9972/8021/6396/26523/5432/8480 27 Human_papillomavirus_type_18 R-HSA-176033 Interactions of Vpr with host cellular proteins 13/1364 36/10654 3.118524908914971e-4 7.462828394744497e-4 3.301632699429297e-4 5903/7175/9631/3159/23636/292/4927/9688/23225/9972/8021/6396/8480 13 Human_papillomavirus_type_18 R-HSA-427413 NoRC negatively regulates rRNA expression 27/1364 107/10654 3.383355888229568e-4 8.081015409963699e-4 3.575125047886305e-4 8467/5434/5440/902/9015/1786/9014/5441/51082/5435/8819/4331/9013/23309/64426/79685/5437/2965/2068/3066/3065/2071/2968/6908/25942/10284/1022 27 Human_papillomavirus_type_18 R-HSA-381042 PERK regulates gene expression 12/1364 32/10654 3.533044553061419e-4 8.40620945383579e-4 3.718994266380441e-4 4802/1051/3576/4800/8894/3309/4801/6347/11340/467/23016/54512 12 Human_papillomavirus_type_18 R-HSA-5626467 RHO GTPases activate IQGAPs 12/1364 32/10654 3.533044553061419e-4 8.40620945383579e-4 3.718994266380441e-4 1499/51807/7277/7846/999/998/8826/10383/60/84790/7280/4221 12 Human_papillomavirus_type_18 R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 14/1364 41/10654 3.6154825847926745e-4 8.58590701780593e-4 3.798494332820321e-4 5903/7175/9631/23636/81608/4927/9688/23225/10189/9972/8021/6396/8480/55339 14 Human_papillomavirus_type_18 R-HSA-167044 Signalling to RAS 9/1364 20/10654 4.0148523504965507e-4 9.497993560603268e-4 4.2020108811212023e-4 4893/6714/5898/1432/5603/3845/5600/3265/6300 9 Human_papillomavirus_type_18 R-HSA-8876384 Listeria monocytogenes entry into host cells 9/1364 20/10654 4.0148523504965507e-4 9.497993560603268e-4 4.2020108811212023e-4 1499/7316/4233/6714/999/6233/7311/10254/7314 9 Human_papillomavirus_type_18 R-HSA-450302 activated TAK1 mediates p38 MAPK activation 10/1364 24/10654 4.087280718610957e-4 9.650955613146023e-4 4.269682879957814e-4 5606/7316/1432/10454/7189/6233/7311/5600/7334/7314 10 Human_papillomavirus_type_18 R-HSA-429914 Deadenylation-dependent mRNA decay 17/1364 56/10654 4.3450285625308896e-4 0.0010240086289683805 4.5303204027586627e-4 9924/4849/4850/26986/9337/25904/246175/4848/23019/1973/55571/11340/57472/85456/29883/23016/54512 17 Human_papillomavirus_type_18 R-HSA-111461 Cytochrome c-mediated apoptotic response 7/1364 13/10654 4.7127787197212963e-4 0.0011064784820215218 4.895175587890791e-4 842/5594/54205/836/331/317/5595 7 Human_papillomavirus_type_18 R-HSA-2892247 POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation 7/1364 13/10654 4.7127787197212963e-4 0.0011064784820215218 4.895175587890791e-4 7547/6657/5460/6774/57167/79923/2247 7 Human_papillomavirus_type_18 R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 14/1364 42/10654 4.7922760184659387e-4 0.0011230201537612635 4.968357659660815e-4 5903/7175/9631/23636/81608/4927/9688/23225/10189/9972/8021/6396/8480/55339 14 Human_papillomavirus_type_18 R-HSA-180910 Vpr-mediated nuclear import of PICs 12/1364 33/10654 4.911849292084962e-4 0.001146713688114572 5.073180313550357e-4 5903/7175/9631/3159/23636/4927/9688/23225/9972/8021/6396/8480 12 Human_papillomavirus_type_18 R-HSA-1980145 Signaling by NOTCH2 12/1364 33/10654 4.911849292084962e-4 0.001146713688114572 5.073180313550357e-4 55534/84441/10046/7316/2033/9794/6233/1385/7311/3516/5663/7314 12 Human_papillomavirus_type_18 R-HSA-437239 Recycling pathway of L1 15/1364 47/10654 5.162231805750881e-4 0.0012006539143712724 5.311817470139878e-4 51807/5594/7277/8650/6714/7846/6195/6196/1213/10383/1211/60/84790/6197/7280 15 Human_papillomavirus_type_18 R-HSA-9020591 Interleukin-12 signaling 15/1364 47/10654 5.162231805750881e-4 0.0012006539143712724 5.311817470139878e-4 6627/27250/5908/3313/6175/3185/5898/6950/3717/3181/998/6648/302/4282/5721 15 Human_papillomavirus_type_18 R-HSA-199418 Negative regulation of the PI3K/AKT network 27/1364 110/10654 5.424471366475634e-4 0.0012592884929276144 5.571222928283878e-4 5290/3815/207/5594/2064/2100/1950/4233/6714/2099/5519/5159/2247/10000/5728/2264/3630/2066/7189/208/5527/5518/1956/5156/5595/5515/5516 27 Human_papillomavirus_type_18 R-HSA-447115 Interleukin-12 family signaling 17/1364 57/10654 5.464553798824097e-4 0.001266226831742449 5.601918858967358e-4 6627/27250/5908/3313/6175/3185/6774/6772/5898/6950/3717/3181/998/6648/302/4282/5721 17 Human_papillomavirus_type_18 R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK 11/1364 29/10654 5.541404200122035e-4 0.0012768875726440756 5.64908308263588e-4 5563/51422/7249/53632/5571/6794/10542/2475/5562/5564/5565 11 Human_papillomavirus_type_18 R-HSA-5205647 Mitophagy 11/1364 29/10654 5.541404200122035e-4 0.0012768875726440756 5.64908308263588e-4 139341/1459/8878/1460/7316/1457/6714/81631/6233/7311/7314 11 Human_papillomavirus_type_18 R-HSA-5654732 Negative regulation of FGFR3 signaling 11/1364 29/10654 5.541404200122035e-4 0.0012768875726440756 5.64908308263588e-4 5594/7316/6714/2247/6233/7311/5518/7314/5595/5515/5516 11 Human_papillomavirus_type_18 R-HSA-174437 Removal of the Flap Intermediate from the C-strand 6/1364 10/10654 5.77506133571242e-4 0.0013209256314833935 5.84391202334377e-4 6118/1763/5111/6119/6117/10714 6 Human_papillomavirus_type_18 R-HSA-2465910 MASTL Facilitates Mitotic Progression 6/1364 10/10654 5.77506133571242e-4 0.0013209256314833935 5.84391202334377e-4 891/983/5519/5518/5515/5516 6 Human_papillomavirus_type_18 R-HSA-8866904 Negative regulation of activity of TFAP2 (AP-2) family transcription factors 6/1364 10/10654 5.77506133571242e-4 0.0013209256314833935 5.84391202334377e-4 7020/7021/51741/7341/7022/7329 6 Human_papillomavirus_type_18 R-HSA-937042 IRAK2 mediated activation of TAK1 complex 6/1364 10/10654 5.77506133571242e-4 0.0013209256314833935 5.84391202334377e-4 7316/10454/7189/6233/7311/7314 6 Human_papillomavirus_type_18 R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 8/1364 17/10654 5.88746987469854e-4 0.001344161320657277 5.946709122663772e-4 1147/4790/7098/5970/4792/4793/1660/3551 8 Human_papillomavirus_type_18 R-HSA-75893 TNF signaling 14/1364 43/10654 6.279783176506386e-4 0.0014310992119671434 6.33133137254724e-4 7124/1147/841/27005/7316/7128/10616/10454/6233/7311/331/1540/3551/7314 14 Human_papillomavirus_type_18 R-HSA-159227 Transport of the SLBP independent Mature mRNA 12/1364 34/10654 6.716784014711264e-4 0.0015250906300313329 6.747159156507803e-4 5903/7175/9631/23636/4927/9688/23225/10189/9972/8021/6396/8480 12 Human_papillomavirus_type_18 R-HSA-4791275 Signaling by WNT in cancer 12/1364 34/10654 6.716784014711264e-4 0.0015250906300313329 6.747159156507803e-4 27123/1487/1499/1452/5519/2932/54894/8312/5527/5518/5515/5516 12 Human_papillomavirus_type_18 R-HSA-191859 snRNP Assembly 16/1364 53/10654 6.802683832560332e-4 0.001538967817857911 6.808553275038814e-4 5903/11218/7175/6606/9631/23636/4927/9688/23225/79084/9972/6634/10419/8021/6396/8480 16 Human_papillomavirus_type_18 R-HSA-194441 Metabolism of non-coding RNA 16/1364 53/10654 6.802683832560332e-4 0.001538967817857911 6.808553275038814e-4 5903/11218/7175/6606/9631/23636/4927/9688/23225/79084/9972/6634/10419/8021/6396/8480 16 Human_papillomavirus_type_18 R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 11/1364 30/10654 7.748134432298348e-4 0.0017464941860098999 7.726671456031594e-4 4893/2904/5594/6195/816/1385/6196/6197/3845/3265/5595 11 Human_papillomavirus_type_18 R-HSA-525793 Myogenesis 11/1364 30/10654 7.748134432298348e-4 0.0017464941860098999 7.726671456031594e-4 6925/25/1499/4209/4205/1432/4208/998/4207/5600/6300 11 Human_papillomavirus_type_18 R-HSA-194138 Signaling by VEGF 26/1364 107/10654 8.021457818010786e-4 0.0018048280090524269 7.98474634058282e-4 5590/4893/857/5290/1499/5747/207/7422/3315/6714/1432/10000/3320/4846/5603/998/208/1398/5580/2475/3791/60/3845/5600/3265/6300 26 Human_papillomavirus_type_18 R-HSA-69166 Removal of the Flap Intermediate 7/1364 14/10654 8.387143580723708e-4 0.0018836948150558488 8.333661271795518e-4 6118/1763/5422/5111/6119/6117/10714 7 Human_papillomavirus_type_18 R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 12/1364 35/10654 9.045272470930934e-4 0.0020241852989002196 8.955205746469318e-4 5903/7175/9631/23636/4927/9688/23225/10189/9972/8021/6396/8480 12 Human_papillomavirus_type_18 R-HSA-9615710 Microautophagy 12/1364 35/10654 9.045272470930934e-4 0.0020241852989002196 8.955205746469318e-4 1080/10013/7316/3043/128866/6233/7311/7251/7431/3312/11315/7314 12 Human_papillomavirus_type_18 R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 8/1364 18/10654 9.415423715563248e-4 0.0021032295422175455 9.304905678765647e-4 8805/5290/613/6776/6774/6772/6777/7750 8 Human_papillomavirus_type_18 R-HSA-6783310 Fanconi Anemia Pathway 13/1364 40/10654 9.928794204443515e-4 0.0022139250272744785 9.79463398794201e-4 6118/2176/545/7316/6119/84126/7398/57599/6233/2067/7311/6117/7314 13 Human_papillomavirus_type_18 R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 11/1364 31/10654 0.0010636678669286278 0.0023632835254478635 0.0010455411477953934 5903/7175/9631/23636/4927/9688/23225/9972/8021/6396/8480 11 Human_papillomavirus_type_18 R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 11/1364 31/10654 0.0010636678669286278 0.0023632835254478635 0.0010455411477953934 5903/7175/9631/23636/4927/9688/23225/9972/8021/6396/8480 11 Human_papillomavirus_type_18 R-HSA-5654736 Signaling by FGFR1 15/1364 50/10654 0.0010658982101441705 0.0023640099589268926 0.0010458625295023628 4893/5290/5594/7316/6714/2247/6233/7311/5518/3845/3265/7314/5595/5515/5516 15 Human_papillomavirus_type_18 R-HSA-111458 Formation of apoptosome 6/1364 11/10654 0.0011330501656359178 0.00249070496587577 0.0011019137148802034 842/5594/54205/331/317/5595 6 Human_papillomavirus_type_18 R-HSA-174414 Processive synthesis on the C-strand of the telomere 6/1364 11/10654 0.0011330501656359178 0.00249070496587577 0.0011019137148802034 6118/1763/5111/6119/6117/10714 6 Human_papillomavirus_type_18 R-HSA-8934903 Receptor Mediated Mitophagy 6/1364 11/10654 0.0011330501656359178 0.00249070496587577 0.0011019137148802034 139341/1459/1460/1457/6714/81631 6 Human_papillomavirus_type_18 R-HSA-9627069 Regulation of the apoptosome activity 6/1364 11/10654 0.0011330501656359178 0.00249070496587577 0.0011019137148802034 842/5594/54205/331/317/5595 6 Human_papillomavirus_type_18 R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 6/1364 11/10654 0.0011330501656359178 0.00249070496587577 0.0011019137148802034 7316/10454/7189/6233/7311/7314 6 Human_papillomavirus_type_18 R-HSA-6802957 Oncogenic MAPK signaling 19/1364 71/10654 0.0011612767036179128 0.002548243225960155 0.0011273692380296644 4000/8805/4893/10018/5594/5908/10533/6714/3717/816/8826/60/3845/3265/369/4763/5245/7529/5595 19 Human_papillomavirus_type_18 R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress 10/1364 27/10654 0.0012243095827671722 0.0026723945550032125 0.0011822950739144647 4802/1051/3576/4800/4801/6347/11340/467/23016/54512 10 Human_papillomavirus_type_18 R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 10/1364 27/10654 0.0012243095827671722 0.0026723945550032125 0.0011822950739144647 1612/842/355/841/8797/836/8837/1613/26060/8795 10 Human_papillomavirus_type_18 R-HSA-76066 RNA Polymerase III Transcription Initiation From Type 2 Promoter 10/1364 27/10654 0.0012243095827671722 0.0026723945550032125 0.0011822950739144647 5434/5440/9330/5441/2972/51082/5435/5437/9329/6908 10 Human_papillomavirus_type_18 R-HSA-5637810 Constitutive Signaling by EGFRvIII 7/1364 15/10654 0.0013997197693336443 0.0030286619399170493 0.0013399114608328671 4893/5290/1950/3320/1956/3845/3265 7 Human_papillomavirus_type_18 R-HSA-5637812 Signaling by EGFRvIII in Cancer 7/1364 15/10654 0.0013997197693336443 0.0030286619399170493 0.0013399114608328671 4893/5290/1950/3320/1956/3845/3265 7 Human_papillomavirus_type_18 R-HSA-69183 Processive synthesis on the lagging strand 7/1364 15/10654 0.0013997197693336443 0.0030286619399170493 0.0013399114608328671 6118/1763/5422/5111/6119/6117/10714 7 Human_papillomavirus_type_18 R-HSA-844456 The NLRP3 inflammasome 7/1364 15/10654 0.0013997197693336443 0.0030286619399170493 0.0013399114608328671 834/351/4790/7295/5970/10628/3326 7 Human_papillomavirus_type_18 R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 7/1364 15/10654 0.0013997197693336443 0.0030286619399170493 0.0013399114608328671 3665/7316/7189/6233/7311/7334/7314 7 Human_papillomavirus_type_18 R-HSA-1251985 Nuclear signaling by ERBB4 11/1364 32/10654 0.001435762987302303 0.0031012480525729746 0.0013720243100627957 5241/51741/6776/9611/6714/2099/2066/3925/6285/5663/6387 11 Human_papillomavirus_type_18 R-HSA-5689901 Metalloprotease DUBs 12/1364 37/10654 0.0015732550461294772 0.003392331193216685 0.0015008025111103568 10617/51720/580/7316/10213/8850/2033/6233/672/7311/79184/7314 12 Human_papillomavirus_type_18 R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 13/1364 42/10654 0.0016476529135508974 0.003546594313050632 0.0015690501156135517 10694/1459/10575/1460/7203/10576/908/1457/6950/2783/10574/22948/10693 13 Human_papillomavirus_type_18 R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 14/1364 47/10654 0.0016716540593193444 0.0035734842369614904 0.0015809464969013458 4893/5594/5908/6714/3717/816/8826/60/3845/3265/369/5245/7529/5595 14 Human_papillomavirus_type_18 R-HSA-6802949 Signaling by RAS mutants 14/1364 47/10654 0.0016716540593193444 0.0035734842369614904 0.0015809464969013458 4893/5594/5908/6714/3717/816/8826/60/3845/3265/369/5245/7529/5595 14 Human_papillomavirus_type_18 R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 14/1364 47/10654 0.0016716540593193444 0.0035734842369614904 0.0015809464969013458 4893/5594/5908/6714/3717/816/8826/60/3845/3265/369/5245/7529/5595 14 Human_papillomavirus_type_18 R-HSA-9649948 Signaling downstream of RAS mutants 14/1364 47/10654 0.0016716540593193444 0.0035734842369614904 0.0015809464969013458 4893/5594/5908/6714/3717/816/8826/60/3845/3265/369/5245/7529/5595 14 Human_papillomavirus_type_18 R-HSA-76061 RNA Polymerase III Transcription Initiation From Type 1 Promoter 10/1364 28/10654 0.0016886681682437255 0.0036036526889324863 0.0015942933330136096 5434/5440/9330/5441/2972/51082/5435/5437/9329/6908 10 Human_papillomavirus_type_18 R-HSA-5654726 Negative regulation of FGFR1 signaling 11/1364 33/10654 0.0019080520163492001 0.004064838086287661 0.0017983265370303918 5594/7316/6714/2247/6233/7311/5518/7314/5595/5515/5516 11 Human_papillomavirus_type_18 R-HSA-5627123 RHO GTPases activate PAKs 9/1364 24/10654 0.0019382830821969878 0.004115124082202835 0.0018205735832781422 4638/4659/4627/2316/4771/10398/4637/998/4628 9 Human_papillomavirus_type_18 R-HSA-982772 Growth hormone receptor signaling 9/1364 24/10654 0.0019382830821969878 0.004115124082202835 0.0018205735832781422 5594/6776/6774/6772/8651/4067/3717/6777/5595 9 Human_papillomavirus_type_18 R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 6/1364 12/10654 0.0020215917691143483 0.004284670609624608 0.001895582725844602 3665/7098/7316/6233/7311/7314 6 Human_papillomavirus_type_18 R-HSA-5655302 Signaling by FGFR1 in disease 12/1364 38/10654 0.0020357111153103346 0.004307245664762241 0.0019055701644257056 8805/4893/5290/613/6776/6774/6772/2247/3845/6777/3265/7750 12 Human_papillomavirus_type_18 R-HSA-2559586 DNA Damage/Telomere Stress Induced Senescence 20/1364 80/10654 0.0021488905856901263 0.004538983175896491 0.002008093243340934 1017/9134/3159/7290/10111/1027/898/5925/472/29855/890/1026/10524/4683/25842/7157/8900/8091/57634/23523 20 Human_papillomavirus_type_18 R-HSA-193704 p75 NTR receptor-mediated signalling 23/1364 97/10654 0.002211765691728036 0.004647993620486305 0.0020563205948757116 4804/8841/4790/10018/7531/29/8878/1894/7316/9828/5970/4792/836/3066/3065/7189/6233/7311/26574/5599/3551/5663/7314 23 Human_papillomavirus_type_18 R-HSA-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function 23/1364 97/10654 0.002211765691728036 0.004647993620486305 0.0020563205948757116 55904/9070/11091/8085/57690/5929/27327/192670/10398/23309/8850/2033/192669/3065/23112/58508/25942/9739/4343/3276/26523/7057/4297 23 Human_papillomavirus_type_18 R-HSA-156711 Polo-like kinase mediated events 7/1364 16/10654 0.002215468778846935 0.004647993620486305 0.0020563205948757116 2305/891/5928/2033/995/5347/7465 7 Human_papillomavirus_type_18 R-HSA-1963640 GRB2 events in ERBB2 signaling 7/1364 16/10654 0.002215468778846935 0.004647993620486305 0.0020563205948757116 4893/2064/1950/2066/1956/3845/3265 7 Human_papillomavirus_type_18 R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 24/1364 103/10654 0.0023033345778727546 0.004824184731396225 0.002134269370106644 5290/3815/207/5594/2064/2100/1950/4233/6714/2099/5519/5159/2247/2264/3630/2066/7189/5527/5518/1956/5156/5595/5515/5516 24 Human_papillomavirus_type_5 R-HSA-2990846 SUMOylation 18/71 188/10654 1.6660237137445768e-16 6.897338174902547e-14 3.735400537132576e-14 1616/7329/142/28996/6672/5371/7341/59343/1387/29843/7157/1487/2033/4193/6612/8554/6613/8535 18 Human_papillomavirus_type_5 R-HSA-3899300 SUMOylation of transcription cofactors 11/71 45/10654 4.3552731847977034e-15 9.015415492531246e-13 4.882490465062688e-13 1616/7329/28996/7341/1387/1487/2033/6612/8554/6613/8535 11 Human_papillomavirus_type_5 R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 16/71 182/10654 3.824792863495487e-14 5.2782141516237725e-12 2.858529403243995e-12 1616/7329/142/28996/6672/5371/7341/1387/7157/1487/2033/4193/6612/8554/6613/8535 16 Human_papillomavirus_type_5 R-HSA-3215018 Processing and activation of SUMO 6/71 10/10654 1.4520273064609804e-11 1.5028482621871147e-9 8.138995165162862e-10 7329/7341/59343/29843/6612/6613 6 Human_papillomavirus_type_5 R-HSA-3232118 SUMOylation of transcription factors 7/71 20/10654 3.119996079647903e-11 2.5833567539484638e-9 1.3990719262421122e-9 7329/7341/7157/4193/6612/8554/6613 7 Human_papillomavirus_type_5 R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 9/71 77/10654 1.7295907488478181e-9 1.1934176167049944e-7 6.463207535168161e-8 7329/142/6672/5371/7341/6612/8554/6613/8535 9 Human_papillomavirus_type_5 R-HSA-5633007 Regulation of TP53 Activity 11/71 160/10654 7.313121602611291e-9 4.3251890621158207e-7 2.342398347904067e-7 8626/1616/28996/5300/5371/7161/7157/2033/4193/94241/4194 11 Human_papillomavirus_type_5 R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 5/71 20/10654 1.6344084420834449e-7 8.458063687781827e-6 4.580644712681233e-6 8626/7161/1387/7157/94241 5 Human_papillomavirus_type_5 R-HSA-5696395 Formation of Incision Complex in GG-NER 6/71 43/10654 3.54561033086396e-7 1.6309807521974215e-5 8.83292398215232e-6 7329/142/7341/6612/8554/6613 6 Human_papillomavirus_type_5 R-HSA-8878171 Transcriptional regulation by RUNX1 11/71 239/10654 4.498159013214644e-7 1.8622378314708627e-5 1.0085345998049675e-5 4602/865/8312/28996/5371/7161/25/1387/2033/8535/861 11 Human_papillomavirus_type_5 R-HSA-5688426 Deubiquitination 12/71 297/10654 5.189841616633063e-7 1.9532676629873525e-5 1.0578337457826242e-5 4087/4088/6478/7706/4086/8312/10454/7157/6885/2033/4193/4194 12 Human_papillomavirus_type_5 R-HSA-5578768 Physiological factors 4/71 12/10654 8.609769258718117e-7 2.97037039425775e-5 1.608667414128911e-5 28996/1482/4878/2626 4 Human_papillomavirus_type_5 R-HSA-8878166 Transcriptional regulation by RUNX2 8/71 121/10654 1.2839096074202451e-6 4.0887582882460116e-5 2.2143542217045522e-5 55294/8454/4086/865/8493/25/861/10273 8 Human_papillomavirus_type_5 R-HSA-4090294 SUMOylation of intracellular receptors 5/71 30/10654 1.4265668144045272e-6 4.2185618654533875e-5 2.284652116301987e-5 7329/7341/6612/8554/6613 5 Human_papillomavirus_type_5 R-HSA-5689880 Ub-specific processing proteases 10/71 220/10654 1.765290922776241e-6 4.8722029468624256e-5 2.638645379307644e-5 4087/4088/6478/4086/8312/10454/7157/6885/4193/4194 10 Human_papillomavirus_type_5 R-HSA-2032785 YAP1- and WWTR1 (TAZ)-stimulated gene expression 4/71 15/10654 2.338584738431702e-6 6.0510880106920294e-5 3.277095718986529e-5 28996/1482/4878/2626 4 Human_papillomavirus_type_5 R-HSA-8878159 Transcriptional regulation by RUNX3 7/71 96/10654 3.21333930587744e-6 7.825426309607413e-5 4.238026452952908e-5 4088/865/1387/7157/2033/4193/861 7 Human_papillomavirus_type_5 R-HSA-3700989 Transcriptional Regulation by TP53 12/71 365/10654 4.507362386360468e-6 9.504714189897903e-5 5.1474806062757505e-5 8626/1616/28996/5300/5371/7161/1387/7157/2033/4193/94241/4194 12 Human_papillomavirus_type_5 R-HSA-3232142 SUMOylation of ubiquitinylation proteins 5/71 38/10654 4.821231835455458e-6 9.504714189897903e-5 5.1474806062757505e-5 7329/5371/7341/4193/8554 5 Human_papillomavirus_type_5 R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 5/71 38/10654 4.821231835455458e-6 9.504714189897903e-5 5.1474806062757505e-5 7329/4605/7341/1387/2033 5 Human_papillomavirus_type_5 R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 5/71 38/10654 4.821231835455458e-6 9.504714189897903e-5 5.1474806062757505e-5 865/28996/2033/8535/861 5 Human_papillomavirus_type_5 R-HSA-6804760 Regulation of TP53 Activity through Methylation 4/71 19/10654 6.508095703503638e-6 1.2247052823865937e-4 6.632652559073085e-5 7157/2033/4193/4194 4 Human_papillomavirus_type_5 R-HSA-4551638 SUMOylation of chromatin organization proteins 6/71 71/10654 7.1931806959034716e-6 1.2947725252626248e-4 7.012116650926496e-5 7329/7341/6612/8554/6613/8535 6 Human_papillomavirus_type_5 R-HSA-5696398 Nucleotide Excision Repair 7/71 111/10654 8.460341701754318e-6 1.45940894355262e-4 7.903740274007322e-5 7329/142/7341/2033/6612/8554/6613 7 Human_papillomavirus_type_5 R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 5/71 44/10654 1.0112969206007406e-5 1.6747077005148264e-4 9.069736593177169e-5 8626/7161/1387/7157/94241 5 Human_papillomavirus_type_5 R-HSA-73894 DNA Repair 11/71 334/10654 1.160269804077938e-5 1.8475065341856398e-4 1.0005565516947402e-4 7329/142/7706/6047/7341/25/7157/2033/6612/8554/6613 11 Human_papillomavirus_type_5 R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 4/71 23/10654 1.4571801293208816e-5 2.234342864958685e-4 1.2100560138220185e-4 4087/4088/142/6497 4 Human_papillomavirus_type_5 R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 6/71 84/10654 1.907265960411077e-5 2.726272621795329e-4 1.4764710613841977e-4 7329/142/7341/6612/8554/6613 6 Human_papillomavirus_type_5 R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 6/71 85/10654 2.0414118665617197e-5 2.726272621795329e-4 1.4764710613841977e-4 8454/10454/8945/23118/6885/4214 6 Human_papillomavirus_type_5 R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 6/71 85/10654 2.0414118665617197e-5 2.726272621795329e-4 1.4764710613841977e-4 8454/10454/8945/23118/6885/4214 6 Human_papillomavirus_type_5 R-HSA-975871 MyD88 cascade initiated on plasma membrane 6/71 85/10654 2.0414118665617197e-5 2.726272621795329e-4 1.4764710613841977e-4 8454/10454/8945/23118/6885/4214 6 Human_papillomavirus_type_5 R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 6/71 92/10654 3.2086655597502675e-5 3.8178163461396835e-4 2.0676198365821315e-4 28996/5300/7157/4193/94241/4194 6 Human_papillomavirus_type_5 R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 6/71 92/10654 3.2086655597502675e-5 3.8178163461396835e-4 2.0676198365821315e-4 8454/10454/8945/23118/6885/4214 6 Human_papillomavirus_type_5 R-HSA-937042 IRAK2 mediated activation of TAK1 complex 3/71 10/10654 3.291471728884955e-5 3.8178163461396835e-4 2.0676198365821315e-4 10454/23118/6885 3 Human_papillomavirus_type_5 R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 3/71 10/10654 3.291471728884955e-5 3.8178163461396835e-4 2.0676198365821315e-4 23411/1387/2033 3 Human_papillomavirus_type_5 R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 6/71 93/10654 3.4120580871296686e-5 3.8178163461396835e-4 2.0676198365821315e-4 8454/10454/8945/23118/6885/4214 6 Human_papillomavirus_type_5 R-HSA-975155 MyD88 dependent cascade initiated on endosome 6/71 93/10654 3.4120580871296686e-5 3.8178163461396835e-4 2.0676198365821315e-4 8454/10454/8945/23118/6885/4214 6 Human_papillomavirus_type_5 R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 6/71 95/10654 3.849922681977128e-5 3.9590805743450224e-4 2.144124491064047e-4 8454/10454/8945/23118/6885/4214 6 Human_papillomavirus_type_5 R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 6/71 95/10654 3.849922681977128e-5 3.9590805743450224e-4 2.144124491064047e-4 8454/10454/8945/23118/6885/4214 6 Human_papillomavirus_type_5 R-HSA-5621481 C-type lectin receptors (CLRs) 7/71 142/10654 4.205237143302306e-5 3.9590805743450224e-4 2.144124491064047e-4 8454/10454/8945/23118/1387/6885/2033 7 Human_papillomavirus_type_5 R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 6/71 97/10654 4.3317985987266814e-5 3.9590805743450224e-4 2.144124491064047e-4 8454/10454/8945/23118/6885/4214 6 Human_papillomavirus_type_5 R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 4/71 30/10654 4.3537308920471404e-5 3.9590805743450224e-4 2.144124491064047e-4 10454/23118/6885/8717 4 Human_papillomavirus_type_5 R-HSA-6804758 Regulation of TP53 Activity through Acetylation 4/71 30/10654 4.3537308920471404e-5 3.9590805743450224e-4 2.144124491064047e-4 5300/5371/7157/2033 4 Human_papillomavirus_type_5 R-HSA-4755510 SUMOylation of immune response proteins 3/71 11/10654 4.5041404288820166e-5 3.9590805743450224e-4 2.144124491064047e-4 7329/7341/6612 3 Human_papillomavirus_type_5 R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 3/71 11/10654 4.5041404288820166e-5 3.9590805743450224e-4 2.144124491064047e-4 10454/23118/6885 3 Human_papillomavirus_type_5 R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 3/71 11/10654 4.5041404288820166e-5 3.9590805743450224e-4 2.144124491064047e-4 10454/23118/6885 3 Human_papillomavirus_type_5 R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 6/71 98/10654 4.5902383470666925e-5 3.9590805743450224e-4 2.144124491064047e-4 8454/10454/8945/23118/6885/4214 6 Human_papillomavirus_type_5 R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 6/71 98/10654 4.5902383470666925e-5 3.9590805743450224e-4 2.144124491064047e-4 8454/10454/8945/23118/6885/4214 6 Human_papillomavirus_type_5 R-HSA-9006936 Signaling by TGF-beta family members 6/71 102/10654 5.7504549852922895e-5 4.8517726179722316e-4 2.6275808991306515e-4 4087/4088/142/4086/6497/10273 6 Human_papillomavirus_type_5 R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 3/71 12/10654 5.976821340980286e-5 4.8517726179722316e-4 2.6275808991306515e-4 8626/7161/7157 3 Human_papillomavirus_type_5 R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 3/71 12/10654 5.976821340980286e-5 4.8517726179722316e-4 2.6275808991306515e-4 8626/7161/7157 3 Human_papillomavirus_type_5 R-HSA-450294 MAP kinase activation 5/71 64/10654 6.403833510171249e-5 5.098436679251726e-4 2.7611670802965094e-4 8454/10454/8945/23118/6885 5 Human_papillomavirus_type_5 R-HSA-9614085 FOXO-mediated transcription 5/71 65/10654 6.901811915421897e-5 5.391226666008802e-4 2.9197337397911894e-4 4087/23411/4088/1387/2033 5 Human_papillomavirus_type_5 R-HSA-6804757 Regulation of TP53 Degradation 4/71 36/10654 9.0800395463115e-5 6.915736882760197e-4 3.7453647496260415e-4 1616/7157/4193/4194 4 Human_papillomavirus_type_5 R-HSA-3371568 Attenuation phase 3/71 14/10654 9.794669163752807e-5 6.915736882760197e-4 3.7453647496260415e-4 3303/1387/2033 3 Human_papillomavirus_type_5 R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 3/71 14/10654 9.794669163752807e-5 6.915736882760197e-4 3.7453647496260415e-4 8626/7161/7157 3 Human_papillomavirus_type_5 R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 3/71 14/10654 9.794669163752807e-5 6.915736882760197e-4 3.7453647496260415e-4 8626/7161/7157 3 Human_papillomavirus_type_5 R-HSA-918233 TRAF3-dependent IRF activation pathway 3/71 14/10654 9.794669163752807e-5 6.915736882760197e-4 3.7453647496260415e-4 7706/1387/2033 3 Human_papillomavirus_type_5 R-HSA-400253 Circadian Clock 5/71 70/10654 9.85576029185632e-5 6.915736882760197e-4 3.7453647496260415e-4 8454/23411/8945/1387/2033 5 Human_papillomavirus_type_5 R-HSA-6806003 Regulation of TP53 Expression and Degradation 4/71 37/10654 1.0129637720675043e-4 6.989450027265779e-4 3.7852856745680425e-4 1616/7157/4193/4194 4 Human_papillomavirus_type_5 R-HSA-448424 Interleukin-17 signaling 5/71 72/10654 1.1276818118208179e-4 7.547358892454033e-4 4.087433114906455e-4 8454/10454/8945/23118/6885 5 Human_papillomavirus_type_5 R-HSA-5693532 DNA Double-Strand Break Repair 7/71 166/10654 1.130280800319203e-4 7.547358892454033e-4 4.087433114906455e-4 7329/142/6047/7341/25/7157/6613 7 Human_papillomavirus_type_5 R-HSA-170834 Signaling by TGF-beta Receptor Complex 5/71 73/10654 1.2043784289215542e-4 7.914486818627356e-4 4.286259070347385e-4 4087/4088/142/6497/10273 5 Human_papillomavirus_type_5 R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 3/71 16/10654 1.492517049617791e-4 9.654719664715085e-4 5.22871926922022e-4 10454/23118/6885 3 Human_papillomavirus_type_5 R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 5/71 78/10654 1.6497154825525335e-4 0.0010507418611949981 5.690516563298618e-4 7706/5300/1387/2033/4214 5 Human_papillomavirus_type_5 R-HSA-4655427 SUMOylation of DNA methylation proteins 3/71 17/10654 1.8036921559551404e-4 0.0010981302243609236 5.94715834703475e-4 7329/7341/8535 3 Human_papillomavirus_type_5 R-HSA-8934593 Regulation of RUNX1 Expression and Activity 3/71 17/10654 1.8036921559551404e-4 0.0010981302243609236 5.94715834703475e-4 865/5371/861 3 Human_papillomavirus_type_5 R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 3/71 17/10654 1.8036921559551404e-4 0.0010981302243609236 5.94715834703475e-4 10454/23118/6885 3 Human_papillomavirus_type_5 R-HSA-75893 TNF signaling 4/71 43/10654 1.83662820348691e-4 0.0011019769220921459 5.967990958698882e-4 10454/23118/6885/8717 4 Human_papillomavirus_type_5 R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 4/71 44/10654 2.010178054629595e-4 0.0011888767351666463 6.438615423099303e-4 4087/4088/142/6497 4 Human_papillomavirus_type_5 R-HSA-2871837 FCERI mediated NF-kB activation 5/71 82/10654 2.08873376460923e-4 0.0011963384825482348 6.479026106859243e-4 8454/10454/8945/23118/6885 5 Human_papillomavirus_type_5 R-HSA-9013694 Signaling by NOTCH4 5/71 82/10654 2.08873376460923e-4 0.0011963384825482348 6.479026106859243e-4 55294/8454/4088/1387/2033 5 Human_papillomavirus_type_5 R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 6/71 129/10654 2.1094857300971292e-4 0.0011963384825482348 6.479026106859243e-4 8454/10454/8945/23118/6885/4214 6 Human_papillomavirus_type_5 R-HSA-4615885 SUMOylation of DNA replication proteins 4/71 45/10654 2.1952505530693631e-4 0.0012281536877982654 6.651328133766347e-4 7329/7341/6612/6613 4 Human_papillomavirus_type_5 R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 6/71 134/10654 2.5933812379962297e-4 0.0013988605799673147 7.575827702340147e-4 8454/10454/8945/23118/6885/4214 6 Human_papillomavirus_type_5 R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 4/71 47/10654 2.6017455231276145e-4 0.0013988605799673147 7.575827702340147e-4 55294/8454/1387/2033 4 Human_papillomavirus_type_5 R-HSA-4570464 SUMOylation of RNA binding proteins 4/71 47/10654 2.6017455231276145e-4 0.0013988605799673147 7.575827702340147e-4 7329/7341/6613/8535 4 Human_papillomavirus_type_5 R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 3/71 20/10654 2.9807681953153425e-4 0.0015821000421289125 8.568200075602806e-4 4088/1387/2033 3 Human_papillomavirus_type_5 R-HSA-5693538 Homology Directed Repair 6/71 138/10654 3.0401211387229846e-4 0.0015931774068750832 8.628191906035917e-4 7329/142/6047/7341/25/6613 6 Human_papillomavirus_type_5 R-HSA-9616222 Transcriptional regulation of granulopoiesis 5/71 90/10654 3.228682530610689e-4 0.0016665819391945918 9.025729800367352e-4 4602/865/5371/2033/861 5 Human_papillomavirus_type_5 R-HSA-446652 Interleukin-1 family signaling 6/71 140/10654 3.285059048770435e-4 0.0016665819391945918 9.025729800367352e-4 8454/4088/10454/8945/23118/6885 6 Human_papillomavirus_type_5 R-HSA-195721 Signaling by WNT 9/71 331/10654 3.30095939647238e-4 0.0016665819391945918 9.025729800367352e-4 8454/1857/8312/51701/8945/1387/6885/1487/2033 9 Human_papillomavirus_type_5 R-HSA-913531 Interferon Signaling 7/71 199/10654 3.4537382056407405e-4 0.0017227079724521283 9.329692299321212e-4 7706/5300/6672/5371/54739/7341/8554 7 Human_papillomavirus_type_5 R-HSA-877300 Interferon gamma signaling 5/71 92/10654 3.575763335037576e-4 0.0017623405008399483 9.544330706303303e-4 7706/6672/5371/7341/8554 5 Human_papillomavirus_type_5 R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 5/71 94/10654 3.950386395080054e-4 0.0019240705500742851 0.001042021426813686 8454/10454/8945/23118/6885 5 Human_papillomavirus_type_5 R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 3/71 23/10654 4.5647449820481357e-4 0.002197447002985963 0.001190074273165548 10454/23118/6885 3 Human_papillomavirus_type_5 R-HSA-9018519 Estrogen-dependent gene expression 6/71 150/10654 4.751618616803863e-4 0.0022611150659273558 0.0012245550700293074 4602/865/8312/1387/2033/861 6 Human_papillomavirus_type_5 R-HSA-166166 MyD88-independent TLR4 cascade 5/71 99/10654 5.016722073944549e-4 0.0023336212793404983 0.0012638223557069057 8454/10454/8945/23118/6885 5 Human_papillomavirus_type_5 R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 5/71 99/10654 5.016722073944549e-4 0.0023336212793404983 0.0012638223557069057 8454/10454/8945/23118/6885 5 Human_papillomavirus_type_5 R-HSA-3371571 HSF1-dependent transactivation 3/71 24/10654 5.19199657610288e-4 0.002362073167589662 0.0012792310823712125 3303/1387/2033 3 Human_papillomavirus_type_5 R-HSA-450302 activated TAK1 mediates p38 MAPK activation 3/71 24/10654 5.19199657610288e-4 0.002362073167589662 0.0012792310823712125 10454/23118/6885 3 Human_papillomavirus_type_5 R-HSA-5607764 CLEC7A (Dectin-1) signaling 5/71 101/10654 5.498978530422851e-4 0.0024741728987079385 0.0013399410816801191 8454/10454/8945/23118/6885 5 Human_papillomavirus_type_5 R-HSA-168898 Toll-like Receptor Cascades 6/71 155/10654 5.654472380825767e-4 0.0024741728987079385 0.0013399410816801191 8454/10454/8945/23118/6885/4214 6 Human_papillomavirus_type_5 R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 4/71 58/10654 5.856737779550193e-4 0.0024741728987079385 0.0013399410816801191 55294/8454/1387/2033 4 Human_papillomavirus_type_5 R-HSA-2644603 Signaling by NOTCH1 in Cancer 4/71 58/10654 5.856737779550193e-4 0.0024741728987079385 0.0013399410816801191 55294/8454/1387/2033 4 Human_papillomavirus_type_5 R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 4/71 58/10654 5.856737779550193e-4 0.0024741728987079385 0.0013399410816801191 55294/8454/1387/2033 4 Human_papillomavirus_type_5 R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 4/71 58/10654 5.856737779550193e-4 0.0024741728987079385 0.0013399410816801191 55294/8454/1387/2033 4 Human_papillomavirus_type_5 R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 4/71 58/10654 5.856737779550193e-4 0.0024741728987079385 0.0013399410816801191 55294/8454/1387/2033 4 Human_papillomavirus_type_5 R-HSA-9020702 Interleukin-1 signaling 5/71 103/10654 6.01530780626555e-4 0.002515492355347412 0.0013623185143376523 8454/10454/8945/23118/6885 5 Human_papillomavirus_type_5 R-HSA-2173788 Downregulation of TGF-beta receptor signaling 3/71 26/10654 6.606184468721856e-4 0.0027349603700508483 0.0014811760966713212 4087/4088/10273 3 Human_papillomavirus_type_5 R-HSA-5663202 Diseases of signal transduction 9/71 377/10654 8.459537131978481e-4 0.003467572646177318 0.0018779378938107519 55294/8454/4087/4088/8312/1387/1487/2033/4193 9 Human_papillomavirus_type_5 R-HSA-933541 TRAF6 mediated IRF7 activation 3/71 29/10654 9.15229670516054e-4 0.0037147557215063366 0.002011805158100304 7706/1387/2033 3 Human_papillomavirus_type_5 R-HSA-157118 Signaling by NOTCH 7/71 235/10654 9.305014238596375e-4 0.0037400736842513587 0.0020255166405937944 55294/8454/4088/1387/7157/2033/861 7 Human_papillomavirus_type_5 R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 8/71 309/10654 9.940826240363734e-4 0.0039572135226063326 0.002143113349390157 55294/8454/6478/6047/6477/8945/26118/10273 8 Human_papillomavirus_type_5 R-HSA-114452 Activation of BH3-only proteins 3/71 30/10654 0.001012084377360011 0.003990504116448044 0.0021611425802273918 8626/7161/7157 3 Human_papillomavirus_type_5 R-HSA-2173789 TGF-beta receptor signaling activates SMADs 3/71 32/10654 0.0012247071653313597 0.004738586602310121 0.0025662825992678762 4087/4088/10273 3 Human_papillomavirus_type_5 R-HSA-8941326 RUNX2 regulates bone development 3/71 32/10654 0.0012247071653313597 0.004738586602310121 0.0025662825992678762 4086/865/25 3 Human_parechovirus_2 R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 69/474 129/10654 1.2701705587520753e-59 1.3425702806009437e-56 7.326878591538289e-57 7322/8454/6500/23643/51135/1147/64127/330/7311/1432/3725/11035/8945/23118/1326/329/246330/7187/1386/23291/10333/841/7099/8517/8772/4615/929/9641/4790/114609/6885/5599/353376/5606/7334/3656/7316/6195/7097/57162/3551/79155/10454/7321/5608/8737/10392/7335/5970/4792/8767/7096/57161/3661/9261/695/4793/3654/4791/7189/7314/6233/10010/5515/148022/3146/7867/257397/4214 69 Human_parechovirus_2 R-HSA-168898 Toll-like Receptor Cascades 73/474 155/10654 7.602363006469198e-58 4.017848848918971e-55 2.1926815408132214e-55 7322/8454/6500/23643/51135/1147/64127/330/7311/1432/3725/11035/8945/23118/1326/329/246330/7187/1386/23291/10333/841/7099/8517/8772/4615/929/9641/7098/4790/114609/6885/5599/353376/5606/7334/3656/7316/6195/7097/57162/3551/79155/10454/7321/30849/5608/8737/10392/7335/5970/4792/8767/7096/5289/57161/3661/9261/695/4793/3654/6279/4791/7189/7314/6233/10010/5515/148022/3146/7867/257397/4214 73 Human_parechovirus_2 R-HSA-166166 MyD88-independent TLR4 cascade 58/474 99/10654 2.880966689860732e-53 7.612954477956984e-51 4.15465722643074e-51 7322/8454/6500/23643/1147/64127/330/7311/1432/3725/11035/8945/23118/1326/329/7187/1386/23291/841/7099/8517/8772/929/9641/4790/6885/5599/353376/5606/7334/3656/7316/6195/3551/79155/10454/7321/5608/8737/10392/7335/5970/4792/8767/3661/9261/4793/3654/4791/7189/7314/6233/10010/5515/148022/3146/7867/257397 58 Human_parechovirus_2 R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 58/474 99/10654 2.880966689860732e-53 7.612954477956984e-51 4.15465722643074e-51 7322/8454/6500/23643/1147/64127/330/7311/1432/3725/11035/8945/23118/1326/329/7187/1386/23291/841/7099/8517/8772/929/9641/4790/6885/5599/353376/5606/7334/3656/7316/6195/3551/79155/10454/7321/5608/8737/10392/7335/5970/4792/8767/3661/9261/4793/3654/4791/7189/7314/6233/10010/5515/148022/3146/7867/257397 58 Human_parechovirus_2 R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 55/474 94/10654 1.7808385458658452e-50 3.764692685960397e-48 2.05452531186207e-48 7322/8454/6500/1147/64127/330/7311/1432/3725/11035/8945/23118/1326/329/7187/1386/23291/841/8517/8772/9641/7098/4790/6885/5599/5606/7334/3656/7316/6195/3551/79155/10454/7321/5608/8737/10392/7335/5970/4792/8767/3661/9261/4793/3654/4791/7189/7314/6233/10010/5515/148022/3146/7867/257397 55 Human_parechovirus_2 R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 55/474 95/10654 4.064767151094269e-50 6.137798398152346e-48 3.349612629773924e-48 8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/23291/10333/7099/8517/4615/929/4790/114609/6885/5599/5606/7334/3656/7316/6195/7097/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/7096/57161/9261/695/4793/3654/4791/7189/7314/6233/5515/3146/7867/257397/4214 55 Human_parechovirus_2 R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 55/474 95/10654 4.064767151094269e-50 6.137798398152346e-48 3.349612629773924e-48 8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/23291/10333/7099/8517/4615/929/4790/114609/6885/5599/5606/7334/3656/7316/6195/7097/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/7096/57161/9261/695/4793/3654/4791/7189/7314/6233/5515/3146/7867/257397/4214 55 Human_parechovirus_2 R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 55/474 98/10654 4.44669443213237e-49 5.222395571959906e-47 2.850045086325777e-47 8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/23291/10333/7099/8517/4615/929/4790/114609/6885/5599/5606/7334/3656/7316/6195/7097/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/7096/57161/9261/695/4793/3654/4791/7189/7314/6233/5515/3146/7867/257397/4214 55 Human_parechovirus_2 R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 55/474 98/10654 4.44669443213237e-49 5.222395571959906e-47 2.850045086325777e-47 8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/23291/10333/7099/8517/4615/929/4790/114609/6885/5599/5606/7334/3656/7316/6195/7097/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/7096/57161/9261/695/4793/3654/4791/7189/7314/6233/5515/3146/7867/257397/4214 55 Human_parechovirus_2 R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 54/474 97/10654 6.277079440809125e-48 6.634872968935245e-46 3.620883719540422e-46 8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/23291/7099/8517/4615/929/4790/6885/5599/353376/5606/7334/3656/7316/6195/57162/3551/79155/10454/30849/5608/10392/7335/5970/4792/8767/5289/57161/9261/4793/3654/4791/7189/7314/6233/5515/148022/3146/7867/257397/4214 54 Human_parechovirus_2 R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 52/474 92/10654 1.2185695358269675e-46 1.1709345448810043e-44 6.390201967781609e-45 8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/23291/7099/8517/4615/929/4790/6885/5599/353376/5606/7334/3656/7316/6195/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/57161/9261/4793/3654/4791/7189/7314/6233/5515/148022/3146/7867/257397/4214 52 Human_parechovirus_2 R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 52/474 93/10654 2.6557917351931543e-46 2.1593629723839723e-44 1.178440381284088e-44 8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/23291/7099/8517/4615/929/4790/6885/5599/353376/5606/7334/3656/7316/6195/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/57161/9261/4793/3654/4791/7189/7314/6233/5515/148022/3146/7867/257397/4214 52 Human_parechovirus_2 R-HSA-975155 MyD88 dependent cascade initiated on endosome 52/474 93/10654 2.6557917351931543e-46 2.1593629723839723e-44 1.178440381284088e-44 8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/23291/7099/8517/4615/929/4790/6885/5599/353376/5606/7334/3656/7316/6195/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/57161/9261/4793/3654/4791/7189/7314/6233/5515/148022/3146/7867/257397/4214 52 Human_parechovirus_2 R-HSA-1632852 Macroautophagy 52/474 95/10654 1.2123076259310752e-45 9.152922575779617e-44 4.995072022633303e-44 2475/51422/7249/8408/7311/1460/5563/23710/64422/7405/84557/5571/10533/5562/53632/84938/11345/115201/55626/84971/26100/9474/7316/65018/6009/83734/5564/9776/11152/23192/5565/8655/30849/79065/5289/57521/7248/55054/9140/81631/55062/140735/11337/22863/440738/8678/6714/8878/7314/6233/60673/9821 52 Human_parechovirus_2 R-HSA-9612973 Autophagy 55/474 119/10654 5.431249093732567e-43 3.6043603202344987e-41 1.9670262963586173e-41 2475/51422/7249/8408/7311/1460/5563/23710/64422/7405/84557/5571/10533/3920/5562/53632/84938/11345/115201/55626/3320/84971/26100/9474/7316/65018/6009/83734/5564/9776/11152/23192/5565/8655/30849/79065/5289/57521/7248/55054/9140/81631/55062/140735/11337/22863/440738/8678/6714/8878/7314/6233/60673/9821/3326 55 Human_parechovirus_2 R-HSA-73887 Death Receptor Signalling 59/474 141/10654 5.4559853475640475e-43 3.6043603202344987e-41 1.9670262963586173e-41 7124/355/1147/330/7128/7311/7132/4804/57142/23118/329/81858/84894/9099/387/843/841/27005/8517/8772/836/4615/10616/331/396/7186/56957/4790/6885/5599/8717/7316/5584/1540/4803/10018/3551/7185/8743/572/10454/8737/5970/4792/8767/55072/8795/356/65078/4974/3654/7189/7375/8878/7314/4099/6233/8797/257397 59 Human_parechovirus_2 R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 47/474 85/10654 1.387039692144861e-41 7.716320813669043e-40 4.211067874212654e-40 8454/6500/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/23291/8517/4615/4790/6885/5599/5606/7334/3656/7316/6195/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/57161/9261/4793/3654/4791/7189/7314/6233/5515/3146/7867/257397/4214 47 Human_parechovirus_2 R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 47/474 85/10654 1.387039692144861e-41 7.716320813669043e-40 4.211067874212654e-40 8454/6500/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/23291/8517/4615/4790/6885/5599/5606/7334/3656/7316/6195/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/57161/9261/4793/3654/4791/7189/7314/6233/5515/3146/7867/257397/4214 47 Human_parechovirus_2 R-HSA-975871 MyD88 cascade initiated on plasma membrane 47/474 85/10654 1.387039692144861e-41 7.716320813669043e-40 4.211067874212654e-40 8454/6500/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/23291/8517/4615/4790/6885/5599/5606/7334/3656/7316/6195/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/57161/9261/4793/3654/4791/7189/7314/6233/5515/3146/7867/257397/4214 47 Human_parechovirus_2 R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 29/474 30/10654 7.866153383647853e-39 4.157262063257891e-37 2.2687642390731708e-37 7124/1147/330/7128/7311/7132/23118/329/81858/9099/27005/8517/10616/331/7186/56957/6885/8717/7316/1540/3551/7185/10454/8737/55072/7375/7314/6233/257397 29 Human_parechovirus_2 R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 36/474 55/10654 7.601847186623802e-36 3.8262630839339805e-34 2.088126445248042e-34 4210/1147/64127/330/7128/7311/1432/23118/29108/329/596/841/8517/598/4790/6885/7334/3656/7316/1540/3551/842/10454/5608/10392/7335/5970/8767/83737/3654/4791/7189/7314/6233/257397/3326 36 Human_parechovirus_2 R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 41/474 78/10654 3.7638964251928683e-35 1.8083811461040282e-33 9.868972445003312e-34 7322/1147/7128/7311/84282/1387/54476/23586/79671/7187/843/841/7706/8517/8772/84166/9641/7186/4790/9474/64135/7316/1540/3551/7321/8737/5970/4792/83737/3661/9140/4793/4791/7189/57506/51191/7314/6233/10010/3146/4214 41 Human_parechovirus_2 R-HSA-75893 TNF signaling 31/474 43/10654 4.472325916944288e-33 2.0553254322652665e-31 1.121663433631794e-31 7124/1147/330/7128/7311/7132/23118/329/81858/9099/841/27005/8517/8772/10616/331/7186/56957/6885/8717/7316/1540/3551/7185/10454/8737/55072/7375/7314/6233/257397 31 Human_parechovirus_2 R-HSA-5357801 Programmed Cell Death 56/474 181/10654 1.492645265668349e-32 6.5738585242143535e-31 3.587585989413401e-31 5716/23643/4000/6093/355/1613/330/7311/23604/7161/11035/329/596/841/7099/999/5588/598/8772/836/331/929/10000/7186/5599/1612/353376/8717/51765/7159/7316/1499/10018/1029/842/8743/572/8655/7082/8737/6774/7157/8795/356/207/8626/54205/140735/208/7314/6233/578/8797/148022/3146/5580 56 Human_parechovirus_2 R-HSA-450294 MAP kinase activation 36/474 64/10654 2.0954170632615451e-32 8.859423343469814e-31 4.834899160704534e-31 8454/6500/1147/64127/7311/1432/3725/8945/23118/1326/1386/23291/8517/4790/6885/5599/5606/7334/3656/7316/6195/3551/79155/10454/5608/10392/7335/8767/9261/3654/7189/7314/6233/5515/7867/257397 36 Human_parechovirus_2 R-HSA-168638 NOD1/2 Signaling Pathway 28/474 36/10654 1.41496809155351e-31 5.7523895106617694e-30 3.1392814338919977e-30 1147/64127/330/7128/7311/1432/23118/329/841/8517/6885/7334/3656/7316/1540/3551/842/10454/5608/10392/7335/8767/83737/3654/7189/7314/6233/257397 28 Human_parechovirus_2 R-HSA-109581 Apoptosis 54/474 178/10654 6.42110735729572e-31 2.5137446209857687e-29 1.3718389207789687e-29 5716/23643/4000/6093/355/1613/7311/23604/7161/329/596/841/7099/999/5588/598/8772/836/331/929/10000/7186/5599/1612/353376/8717/51765/7159/7316/1499/10018/1029/842/8743/572/8655/7082/8737/6774/7157/8795/356/207/8626/54205/140735/208/7314/6233/578/8797/148022/3146/5580 54 Human_parechovirus_2 R-HSA-448424 Interleukin-17 signaling 36/474 72/10654 5.968411110836106e-30 2.2530751943406298e-28 1.229582439375258e-28 8454/6500/1147/64127/7311/1432/3725/8945/23118/1326/1386/23291/8517/4790/6885/5599/5606/7334/3656/7316/6195/3551/79155/10454/5608/10392/7335/8767/9261/3654/7189/7314/6233/5515/7867/257397 36 Human_parechovirus_2 R-HSA-5357905 Regulation of TNFR1 signaling 26/474 33/10654 1.1736807048202441e-29 4.27786381032758e-28 2.334580857500885e-28 7124/1147/330/7128/7311/7132/329/81858/9099/841/27005/8517/10616/331/7186/56957/8717/7316/1540/3551/7185/8737/55072/7375/7314/6233 26 Human_parechovirus_2 R-HSA-450302 activated TAK1 mediates p38 MAPK activation 22/474 24/10654 2.8919596152052882e-28 1.0189337710906633e-26 5.560680242570169e-27 64127/7311/1432/23118/8517/6885/5606/7334/3656/7316/10454/5608/10392/7335/8767/9261/3654/7189/7314/6233/7867/257397 22 Human_parechovirus_2 R-HSA-9020702 Interleukin-1 signaling 40/474 103/10654 7.902898226990422e-28 2.694633363202863e-26 1.4705562744960108e-26 5716/8454/6500/51135/1147/64127/7311/8945/23118/1326/246330/23291/8517/4615/4790/6885/7334/3656/7316/4215/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/57161/4793/3654/4791/7189/8878/7314/6233/3146/257397 40 Human_parechovirus_2 R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 25/474 33/10654 8.661336604166198e-28 2.8609477470636475e-26 1.5613198878562753e-26 1147/64127/7311/23118/8517/4790/6885/7334/3656/7316/3551/10454/10392/7335/5970/4792/8767/4793/3654/4791/7189/7314/6233/3146/257397 25 Human_parechovirus_2 R-HSA-449147 Signaling by Interleukins 81/474 461/10654 9.10481506293296e-28 2.916299855006103e-26 1.5915274814951394e-26 5716/5295/8454/6500/51135/8660/7124/1147/2308/64127/7311/7132/3091/1432/3725/7291/8945/23118/1326/596/246330/1386/1072/23291/8517/598/1438/5290/836/3576/4615/332/1437/3667/3320/4790/8835/6885/5599/84867/5606/2309/7334/3656/5291/7316/6195/4215/57162/3551/79155/10454/5608/10392/6774/3569/7157/7335/5970/4792/8767/57161/356/4170/9261/207/4793/3654/4791/7189/1439/8878/7314/6233/7525/5515/4582/3146/7867/257397/821 81 Human_parechovirus_2 R-HSA-937041 IKK complex recruitment mediated by RIP1 21/474 25/10654 2.8633111079989925e-25 8.901528944573339e-24 4.857877669298601e-24 7322/23643/1147/330/7311/11035/329/7099/8517/929/353376/7334/7316/3551/7321/8737/7335/7189/7314/6233/148022 21 Human_parechovirus_2 R-HSA-446652 Interleukin-1 family signaling 43/474 140/10654 5.1489245690504375e-25 1.5549752198532322e-23 8.486047109292151e-24 5716/8454/6500/51135/1147/64127/7311/8945/23118/1326/246330/23291/8517/4615/4790/6885/5599/84867/7334/3656/7316/4215/57162/3551/79155/10454/5608/10392/6774/7335/5970/4792/8767/57161/4793/3654/4791/7189/8878/7314/6233/3146/257397 43 Human_parechovirus_2 R-HSA-5260271 Diseases of Immune System 20/474 24/10654 5.633798568780772e-24 1.6094392127571019e-22 8.783276289308289e-23 23643/51135/1147/7187/10333/7099/8517/4615/929/7098/4790/114609/7097/3551/5970/4792/7096/695/4791/148022 20 Human_parechovirus_2 R-HSA-5602358 Diseases associated with the TLR signaling cascade 20/474 24/10654 5.633798568780772e-24 1.6094392127571019e-22 8.783276289308289e-23 23643/51135/1147/7187/10333/7099/8517/4615/929/7098/4790/114609/7097/3551/5970/4792/7096/695/4791/148022 20 Human_parechovirus_2 R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 23/474 34/10654 8.771729133180217e-24 2.439925708887234e-22 1.3315533421004873e-22 7322/7128/7311/84282/54476/23586/79671/7187/7706/84166/9641/9474/64135/7316/1540/7321/83737/3661/9140/57506/51191/7314/6233 23 Human_parechovirus_2 R-HSA-5621481 C-type lectin receptors (CLRs) 42/474 142/10654 9.86469855653668e-24 2.6735862498100695e-22 1.4590701238818086e-22 7322/5716/8454/6500/1147/7311/3384/5170/8945/23118/10892/29108/1387/3708/4893/23291/841/8517/4790/3845/6885/7334/7316/3551/10454/7321/9020/7335/5970/4792/5894/84433/997/8915/4791/7189/6714/7314/6233/4582/257397/5580 42 Human_parechovirus_2 R-HSA-5607764 CLEC7A (Dectin-1) signaling 36/474 101/10654 1.2586777836856738e-23 3.326056043389393e-22 1.8151458564730244e-22 7322/5716/8454/6500/1147/7311/5170/8945/23118/10892/29108/3708/23291/841/8517/4790/6885/7334/7316/3551/10454/7321/9020/7335/5970/4792/84433/997/8915/4791/7189/6714/7314/6233/257397/5580 36 Human_parechovirus_2 R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 18/474 20/10654 5.967863735470974e-23 1.4669841786960045e-21 8.005849025797048e-22 7322/1147/330/7311/11035/329/8517/7098/7334/7316/3551/7321/8737/7335/7189/7314/6233/148022 18 Human_parechovirus_2 R-HSA-5213460 RIPK1-mediated regulated necrosis 18/474 20/10654 5.967863735470974e-23 1.4669841786960045e-21 8.005849025797048e-22 355/330/7311/11035/329/841/8772/331/7186/8717/7316/8743/8737/8795/356/7314/6233/8797 18 Human_parechovirus_2 R-HSA-5218859 Regulated Necrosis 18/474 20/10654 5.967863735470974e-23 1.4669841786960045e-21 8.005849025797048e-22 355/330/7311/11035/329/841/8772/331/7186/8717/7316/8743/8737/8795/356/7314/6233/8797 18 Human_parechovirus_2 R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 40/474 134/10654 8.155552663860611e-23 1.9591861740228787e-21 1.0691968564104344e-21 7322/5716/5295/8454/6500/1147/7311/5170/3725/8945/23118/10892/3708/4893/23291/8517/5588/5290/4790/3845/6885/5599/7334/5291/7316/3551/10454/7321/7335/5970/4792/695/84433/997/8915/7189/7314/6233/257397/4214 40 Human_parechovirus_2 R-HSA-5675482 Regulation of necroptotic cell death 17/474 18/10654 1.3717229185267713e-22 3.2220247219617712e-21 1.7583723025793466e-21 355/330/7311/329/841/8772/331/7186/8717/7316/8743/8737/8795/356/7314/6233/8797 17 Human_parechovirus_2 R-HSA-193639 p75NTR signals via NF-kB 16/474 16/10654 1.8449219513859943e-22 4.23930978829347e-21 2.3135405706167622e-21 7311/4804/4615/4790/7316/5584/4803/3551/5970/4792/8767/3654/7189/8878/7314/6233 16 Human_parechovirus_2 R-HSA-5689896 Ovarian tumor domain proteases 23/474 38/10654 4.0177400570774736e-22 9.035640936874233e-21 4.931067304095086e-21 64127/7128/7311/84282/23586/7187/387/7706/8517/56957/64135/7316/5728/79155/7321/8737/10392/7157/8767/7189/57506/7314/6233 23 Human_parechovirus_2 R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 20/474 27/10654 4.156985928308893e-22 9.154029429630208e-21 4.995676071739635e-21 23643/355/1613/23604/841/7099/8772/836/929/7186/1612/353376/8717/842/8743/8737/8795/356/8797/148022 20 Human_parechovirus_2 R-HSA-202424 Downstream TCR signaling 34/474 98/10654 6.227352646824718e-22 1.3433289281007608e-20 7.33101879798055e-21 7322/5716/5295/8454/6500/1147/7311/5170/8945/23118/10892/23291/8517/5588/5290/4790/6885/3115/7334/5291/7316/5728/3551/7321/7335/5970/4792/8767/84433/997/8915/7189/7314/6233 34 Human_parechovirus_2 R-HSA-9006925 Intracellular signaling by second messengers 58/474 305/10654 1.0547609486355562e-21 2.229764645415566e-20 1.2168610523205997e-20 2475/5716/5295/7249/51135/8660/1147/2308/7311/818/1460/5170/3725/3708/2064/1386/1956/5290/2260/5581/4615/3164/331/3667/10000/2100/2309/5291/7316/5728/5468/6009/1822/842/2264/572/3630/7157/57521/8658/207/8975/4734/6045/5987/3654/7189/5578/6714/208/5156/4303/10818/7314/6233/253260/5515/5580 58 Human_parechovirus_2 R-HSA-1257604 PIP3 activates AKT signaling 53/474 264/10654 5.114083230063808e-21 1.0599188184661656e-19 5.784350072394153e-20 2475/5716/5295/7249/51135/8660/1147/2308/7311/1460/5170/3725/2064/1386/1956/5290/2260/4615/3164/331/3667/10000/2100/2309/5291/7316/5728/5468/6009/1822/842/2264/572/3630/7157/57521/8658/207/8975/4734/6045/5987/3654/7189/6714/208/5156/4303/10818/7314/6233/253260/5515 53 Human_parechovirus_2 R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 18/474 23/10654 9.332943302097486e-21 1.8971002058302005e-19 1.0353143582083853e-19 64127/7311/23118/8517/6885/5599/7334/3656/7316/10454/10392/7335/8767/3654/7189/7314/6233/257397 18 Human_parechovirus_2 R-HSA-2871837 FCERI mediated NF-kB activation 30/474 82/10654 2.964148045493952e-20 5.911517894503975e-19 3.2261233941026533e-19 7322/5716/8454/6500/1147/7311/5170/8945/23118/10892/23291/8517/5588/4790/6885/7334/7316/3551/10454/7321/7335/5970/4792/84433/997/8915/7189/7314/6233/257397 30 Human_parechovirus_2 R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 15/474 16/10654 6.565309512362468e-20 1.2850985471420607e-18 7.013235112621117e-19 23643/7311/23118/7099/929/6885/353376/3656/7316/10454/7189/7314/6233/148022/257397 15 Human_parechovirus_2 R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 15/474 17/10654 5.354817113172647e-19 1.0107217301113371e-17 5.515864244395885e-18 23643/355/841/7099/8772/929/7186/353376/8717/8743/8737/8795/356/8797/148022 15 Human_parechovirus_2 R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 15/474 17/10654 5.354817113172647e-19 1.0107217301113371e-17 5.515864244395885e-18 23643/7311/23118/7099/929/6885/353376/3656/7316/10454/7189/7314/6233/148022/257397 15 Human_parechovirus_2 R-HSA-202403 TCR signaling 34/474 119/10654 6.975519814157503e-19 1.2935306041341193e-17 7.059251815620152e-18 7322/5716/5295/8454/6500/1147/7311/5170/8945/23118/10892/23291/8517/5588/5290/4790/6885/3115/7334/5291/7316/5728/3551/7321/7335/5970/4792/8767/84433/997/8915/7189/7314/6233 34 Human_parechovirus_2 R-HSA-5688426 Deubiquitination 53/474 297/10654 1.3445310641116476e-18 2.4502919564931235e-17 1.3372105682997875e-17 5716/672/64127/330/7128/7311/3091/84282/367/9097/23586/329/23032/11274/7187/4287/9099/387/27005/7706/8517/7186/56957/6885/51651/64135/7316/5728/1540/2648/79155/10454/7321/8737/10392/7157/4792/8767/8658/8975/4087/5886/7189/7375/8678/9817/57506/9100/4303/7314/10445/6233/4194 53 Human_parechovirus_2 R-HSA-937039 IRAK1 recruits IKK complex 14/474 15/10654 1.4238152742181784e-18 2.5082879080810243e-17 1.3688610004764243e-17 1147/7311/246330/8517/7334/7316/57162/3551/7335/57161/3654/7189/7314/6233 14 Human_parechovirus_2 R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 14/474 15/10654 1.4238152742181784e-18 2.5082879080810243e-17 1.3688610004764243e-17 1147/7311/246330/8517/7334/7316/57162/3551/7335/57161/3654/7189/7314/6233 14 Human_parechovirus_2 R-HSA-933542 TRAF6 mediated NF-kB activation 17/474 24/10654 2.0572141752257188e-18 3.56471374297309e-17 1.945389763630188e-17 1147/84282/23586/7706/8517/7186/4790/64135/3551/5970/4792/4793/4791/7189/57506/3146/4214 17 Human_parechovirus_2 R-HSA-209543 p75NTR recruits signalling complexes 13/474 13/10654 2.2831341795409862e-18 3.77073879339816e-17 2.0578248855073365e-17 7311/4804/4615/7316/5584/4803/3551/8767/3654/7189/8878/7314/6233 13 Human_parechovirus_2 R-HSA-209560 NF-kB is activated and signals survival 13/474 13/10654 2.2831341795409862e-18 3.77073879339816e-17 2.0578248855073365e-17 7311/4804/4790/7316/4803/3551/5970/4792/3654/7189/8878/7314/6233 13 Human_parechovirus_2 R-HSA-5357786 TNFR1-induced proapoptotic signaling 13/474 13/10654 2.2831341795409862e-18 3.77073879339816e-17 2.0578248855073365e-17 7124/7128/7132/9099/841/27005/8772/7186/56957/8717/1540/8737/7375 13 Human_parechovirus_2 R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 14/474 16/10654 1.093095052788002e-17 1.7775407243029508e-16 9.700665407738059e-17 8454/6500/1147/7311/8945/1326/23291/8517/4790/7316/3551/79155/7314/6233 14 Human_parechovirus_2 R-HSA-1227986 Signaling by ERBB2 22/474 50/10654 3.1595947708596573e-17 5.060138898179784e-16 2.761495908183561e-16 5295/7311/2064/4893/387/1956/5290/5581/10000/3320/3845/7316/207/11140/5578/6714/10193/208/7314/6233/7525/5580 22 Human_parechovirus_2 R-HSA-5663202 Diseases of signal transduction 58/474 377/10654 4.080619530507331e-17 6.437634095143655e-16 3.5132435235161316e-16 2475/5716/5295/7249/8454/6500/4000/5037/8660/1147/2308/7311/818/51009/5170/10533/1387/2064/4893/1956/5290/2260/4140/3164/3667/10000/3320/3845/2100/2309/5291/7316/1499/5728/2648/10018/369/55869/842/2264/572/8315/4296/6774/8658/5894/207/4087/11140/6714/208/5156/4303/10818/7314/6233/253260/5515 58 Human_parechovirus_2 R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12/474 12/10654 5.2591155711418267e-17 8.174831115730752e-16 4.461293085117215e-16 1147/84282/23586/843/841/7706/8517/8772/64135/3551/8737/57506 12 Human_parechovirus_2 R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 14/474 17/10654 5.944313833850646e-17 9.105999597652366e-16 4.9694645018308995e-016 1147/11035/81030/8517/4615/7098/4790/3551/8737/5970/4792/4793/4791/148022 14 Human_parechovirus_2 R-HSA-109606 Intrinsic Pathway for Apoptosis 22/474 53/10654 1.4537917767228634e-16 2.195225582851524e-15 1.1980118701415477e-15 7161/596/841/598/836/331/10000/5599/7159/10018/1029/842/572/8655/6774/7157/207/8626/54205/140735/208/578 22 Human_parechovirus_2 R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 15/474 21/10654 1.8113984246306874e-16 2.696687513851601e-15 1.4716772968089204e-15 1147/11035/81030/8517/4615/7098/4790/3551/8737/5970/4792/3661/4793/4791/148022 15 Human_parechovirus_2 R-HSA-5633007 Regulation of TP53 Activity 36/474 160/10654 3.0345458342021383e-16 4.454881870488417e-15 2.4311858437759824e-15 2475/51422/672/7311/6119/1460/6118/5170/7161/5563/1432/5571/5562/53632/9099/10000/6117/6794/7159/7316/1029/5564/5565/5608/7157/8445/207/8626/6790/22974/208/7314/6233/253260/5515/4194 36 Human_parechovirus_2 R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 23/474 63/10654 8.644891645166186e-16 1.2517329409507752e-14 6.83114725530075e-15 1147/7311/11035/1387/81030/6737/8517/4615/7098/4790/5591/7316/1499/3551/8737/5970/4792/3661/4793/4791/7314/6233/148022 23 Human_parechovirus_2 R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 11/474 11/10654 1.2089150545067498e-15 1.7267881251535603e-14 9.423690609810795e-15 7311/23118/7098/6885/7316/10454/7189/7314/6233/148022/257397 11 Human_parechovirus_2 R-HSA-2219528 PI3K/AKT Signaling in Cancer 28/474 101/10654 2.188580003024019e-15 3.0844387509285177e-14 1.6832867953082984e-14 2475/5295/7249/8660/1147/2308/5170/2064/1956/5290/2260/3164/3667/10000/2100/2309/5291/5728/842/2264/572/207/6714/208/5156/4303/10818/253260 28 Human_parechovirus_2 R-HSA-1169091 Activation of NF-kappaB in B cells 23/474 67/10654 4.134111789102515e-15 5.749679159317576e-14 3.13780229976202e-14 5716/8454/6500/1147/7311/8945/10892/23291/8517/4794/4790/6885/5579/5966/7316/3551/5970/4792/84433/4793/8915/7314/6233 23 Human_parechovirus_2 R-HSA-193704 p75 NTR receptor-mediated signalling 27/474 97/10654 6.269898577125926e-15 8.606860774054681e-14 4.6970668766438935e-14 7311/4804/57142/84894/387/836/4615/396/4790/5599/7316/5584/4803/10018/3551/572/5970/4792/8767/65078/4974/3654/7189/8878/7314/4099/6233 27 Human_parechovirus_2 R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 25/474 83/10654 8.476542147064879e-15 1.1486801345445612e-13 6.268751817262556e-14 5716/8454/6500/1147/7311/8945/10892/4893/23291/8517/4794/4790/3845/6885/5579/5966/7316/3551/5970/4792/84433/4793/8915/7314/6233 25 Human_parechovirus_2 R-HSA-4420097 VEGFA-VEGFR2 Pathway 27/474 99/10654 1.0951838155422876e-14 1.4653282190230354e-13 7.996811870981661e-14 2475/5295/3315/6093/5170/1432/3708/5590/4893/387/5290/10000/3320/3845/5579/5291/1499/8877/9261/207/10458/5578/6714/208/253260/7867/5580 27 Human_parechovirus_2 R-HSA-3700989 Transcriptional Regulation by TP53 53/474 365/10654 1.2463086007124912e-14 1.646685238691379e-13 8.986540963032175e-14 2475/51422/7249/672/355/7311/6119/1460/6118/5170/7161/5563/1432/3725/5571/1387/5562/53632/1386/9099/843/332/10000/6117/6794/7159/1874/7316/5728/6009/1029/5564/5565/5608/7157/10397/8795/665/57521/8445/7248/207/8626/54205/6790/22974/208/7314/6233/253260/8797/5515/4194 53 Human_parechovirus_2 R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 13/474 18/10654 1.5932119938577076e-14 2.0790433055649345e-13 1.1346071119350538e-13 23643/7311/7187/7099/929/9641/353376/7316/3661/7314/6233/10010/148022 13 Human_parechovirus_2 R-HSA-937042 IRAK2 mediated activation of TAK1 complex 10/474 10/10654 2.7732094483124622e-14 3.574734618129601e-13 1.950858507927124e-13 7311/23118/6885/3656/7316/10454/7189/7314/6233/257397 10 Human_parechovirus_2 R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 61/474 473/10654 2.8290999176317706e-14 3.602841702333472e-13 1.9661975331163102e-13 2475/5295/3315/8660/6093/7311/5170/1432/23118/3708/2064/1213/4670/5590/4893/387/1956/5290/4914/2260/5581/3667/10000/3320/3845/5579/5291/7316/1499/6195/4803/8471/2264/3630/30849/6774/8877/11059/5289/83737/9261/207/4734/11140/10413/10458/5578/6714/10193/208/5156/10818/7314/6233/253260/7525/5515/7867/3910/5580/5607 61 Human_parechovirus_2 R-HSA-983705 Signaling by the B Cell Receptor (BCR) 28/474 112/10654 3.9179517983513856e-14 4.930089346258827e-13 2.690523290095939e-13 5716/5295/8454/6500/1147/7311/8945/10892/3708/4893/23291/8517/4794/4790/3845/6885/5579/5966/7316/3551/5970/4792/695/84433/4793/8915/7314/6233 28 Human_parechovirus_2 R-HSA-194138 Signaling by VEGF 27/474 107/10654 8.835551231897843e-14 1.0987267826018848e-12 5.996138792668753e-13 2475/5295/3315/6093/5170/1432/3708/5590/4893/387/5290/10000/3320/3845/5579/5291/1499/8877/9261/207/10458/5578/6714/208/253260/7867/5580 27 Human_parechovirus_2 R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 14/474 25/10654 2.803314752074853e-13 3.440698115879473e-12 1.877710070708511e-12 2475/7249/1147/2308/5170/3164/10000/2309/842/572/207/208/4303/253260 14 Human_parechovirus_2 R-HSA-3371378 Regulation by c-FLIP 10/474 11/10654 2.9296388876930236e-13 3.440698115879473e-12 1.877710070708511e-12 355/841/8772/7186/8717/8743/8737/8795/356/8797 10 Human_parechovirus_2 R-HSA-5218900 CASP8 activity is inhibited 10/474 11/10654 2.9296388876930236e-13 3.440698115879473e-12 1.877710070708511e-12 355/841/8772/7186/8717/8743/8737/8795/356/8797 10 Human_parechovirus_2 R-HSA-5603041 IRAK4 deficiency (TLR2/4) 10/474 11/10654 2.9296388876930236e-13 3.440698115879473e-12 1.877710070708511e-12 23643/51135/10333/7099/4615/929/114609/7097/7096/695 10 Human_parechovirus_2 R-HSA-69416 Dimerization of procaspase-8 10/474 11/10654 2.9296388876930236e-13 3.440698115879473e-12 1.877710070708511e-12 355/841/8772/7186/8717/8743/8737/8795/356/8797 10 Human_parechovirus_2 R-HSA-2262752 Cellular responses to stress 59/474 479/10654 5.923815743840693e-13 6.880739825538035e-12 3.755061917437478e-12 2475/7322/5716/1030/51343/7311/6119/818/3303/3091/6118/7013/367/1432/3725/1387/25913/81929/2034/1019/3576/3309/3320/1780/6117/3490/4790/5599/1021/5606/9448/7316/6195/6009/112399/1029/10935/7321/405/8655/7428/5608/6774/3569/7157/5970/57521/9261/54205/140735/6045/2288/2289/7314/6233/7867/3326/4194/23043 59 Human_parechovirus_2 R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 10/474 12/10654 1.6881409429095488e-12 1.9395271485384707e-11 1.0584682342270398e-11 7311/7187/9641/7098/7316/3661/7314/6233/10010/148022 10 Human_parechovirus_2 R-HSA-5689880 Ub-specific processing proteases 37/474 220/10654 1.7981905323062944e-12 2.0437498845674765e-11 1.1153462498062811e-11 5716/330/7311/3091/367/9097/23586/329/23032/11274/9099/27005/8517/7186/6885/51651/64135/7316/5728/1540/2648/10454/8737/7157/4792/8658/8975/4087/7189/7375/8678/9817/9100/4303/7314/6233/4194 37 Human_parechovirus_2 R-HSA-8953897 Cellular responses to external stimuli 59/474 493/10654 2.049596989846929e-12 2.304706402412983e-11 1.257759406983334e-11 2475/7322/5716/1030/51343/7311/6119/818/3303/3091/6118/7013/367/1432/3725/1387/25913/81929/2034/1019/3576/3309/3320/1780/6117/3490/4790/5599/1021/5606/9448/7316/6195/6009/112399/1029/10935/7321/405/8655/7428/5608/6774/3569/7157/5970/57521/9261/54205/140735/6045/2288/2289/7314/6233/7867/3326/4194/23043 59 Human_parechovirus_2 R-HSA-165159 mTOR signalling 16/474 40/10654 4.300040038701402e-12 4.7843603377972444e-11 2.6109938406740928e-11 2475/51422/7249/5563/5571/5562/53632/6198/6794/6009/5564/5565/57521/7248/207/208 16 Human_parechovirus_2 R-HSA-193697 p75NTR regulates axonogenesis 9/474 10/10654 6.0989734243370856e-12 6.578178479106428e-11 3.589943540855772e-11 4804/57142/84894/387/396/4803/65078/4974/4099 9 Human_parechovirus_2 R-HSA-2562578 TRIF-mediated programmed cell death 9/474 10/10654 6.0989734243370856e-12 6.578178479106428e-11 3.589943540855772e-11 23643/11035/841/7099/8772/929/353376/8737/148022 9 Human_parechovirus_2 R-HSA-5602498 MyD88 deficiency (TLR2/4) 9/474 10/10654 6.0989734243370856e-12 6.578178479106428e-11 3.589943540855772e-11 23643/10333/7099/4615/929/114609/7097/7096/695 9 Human_parechovirus_2 R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 23/474 92/10654 7.75589339182702e-12 8.280787187031475e-11 4.5191170427657706e-11 51422/672/7311/6119/1460/6118/5563/1432/5571/5562/53632/6117/6794/7316/5564/5565/7157/8445/6790/22974/7314/6233/4194 23 Human_parechovirus_2 R-HSA-6804757 Regulation of TP53 Degradation 15/474 36/10654 1.0012094299736753e-11 1.0582783674821749e-10 5.7753975539534114e-11 2475/7311/5170/9099/10000/7316/1029/7157/207/208/7314/6233/253260/5515/4194 15 Human_parechovirus_2 R-HSA-6806003 Regulation of TP53 Expression and Degradation 15/474 37/10654 1.6158679305638505e-11 1.6910617847584059e-10 9.228719394986871e-11 2475/7311/5170/9099/10000/7316/1029/7157/207/208/7314/6233/253260/5515/4194 15 Human_parechovirus_2 R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 9/474 11/10654 3.222601633439206e-11 3.3394999279855304e-10 1.8224826575074152e-10 7311/23118/6885/7316/10454/7189/7314/6233/257397 9 Human_parechovirus_2 R-HSA-983169 Class I MHC mediated antigen processing & presentation 47/474 371/10654 6.152050571050225e-11 6.31331791611659e-10 3.445399808825267e-10 7322/5716/8454/6500/23643/1147/8773/51343/7311/23327/6047/10533/8945/6737/23291/10333/7099/8517/4615/10616/929/3309/8452/9666/114609/9903/7334/7316/7097/3551/7321/135892/7428/7335/7096/11059/83737/695/997/4734/10075/9817/10193/51191/7314/6233/821 47 Human_parechovirus_2 R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 11/474 19/10654 6.599818081443145e-11 6.643816868652766e-10 3.6257647204319236e-10 5295/7311/4893/1956/5290/3320/3845/7316/11140/7314/6233 11 Human_parechovirus_2 R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 11/474 19/10654 6.599818081443145e-11 6.643816868652766e-10 3.6257647204319236e-10 5295/7311/4893/1956/5290/3320/3845/7316/11140/7314/6233 11 Human_parechovirus_2 R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 10/474 15/10654 6.804219478330744e-11 6.784962253392071e-10 3.702792725049899e-10 51135/7311/4615/7334/7316/7335/3654/7189/7314/6233 10 Human_parechovirus_2 R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK 13/474 29/10654 8.037967592797457e-11 7.866788653321214e-10 4.293183470616966e-10 2475/51422/7249/5563/5571/5562/53632/6794/6009/5564/5565/57521/7248 13 Human_parechovirus_2 R-HSA-5205647 Mitophagy 13/474 29/10654 8.037967592797457e-11 7.866788653321214e-10 4.293183470616966e-10 8408/7311/1460/84557/9474/7316/65018/9140/81631/6714/8878/7314/6233 13 Human_parechovirus_2 R-HSA-114452 Activation of BH3-only proteins 13/474 30/10654 1.3615265513269696e-10 1.3203060227088137e-9 7.205374699441617e-10 7161/596/10000/5599/7159/10018/572/8655/7157/207/8626/140735/208 13 Human_parechovirus_2 R-HSA-187037 Signaling by NTRK1 (TRKA) 20/474 80/10654 1.83564373903417e-10 1.763886756508289e-9 9.626150899432777e-10 5295/8660/1432/1213/4893/387/5290/4914/3667/3845/5291/6195/4803/6774/9261/6714/10818/5515/7867/5607 20 Human_parechovirus_2 R-HSA-199418 Negative regulation of the PI3K/AKT network 23/474 110/10654 3.807808451538743e-10 3.6259941741229295e-9 1.9788326519139225e-9 5295/51135/8660/2064/1956/5290/2260/4615/3667/10000/2100/5291/5728/2264/3630/207/3654/7189/6714/208/5156/10818/5515 23 Human_parechovirus_2 R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 9/474 13/10654 3.866714054041659e-10 3.6492113885018157e-9 1.991503103021456e-9 7311/2064/10000/7316/207/10193/208/7314/6233 9 Human_parechovirus_2 R-HSA-2559583 Cellular Senescence 31/474 195/10654 5.17371667834679e-10 4.839485423904918e-9 2.6410775405067916e-9 1030/51343/7311/7013/1432/3725/25913/1019/3576/3490/4790/5599/1021/5606/9448/7316/6195/1029/7321/5608/6774/3569/7157/5970/9261/6045/7314/6233/7867/4194/23043 31 Human_parechovirus_2 R-HSA-918233 TRAF3-dependent IRF activation pathway 9/474 14/10654 1.0401717954031707e-9 9.644399892466241e-9 5.263288493822139e-9 84282/1387/23586/7187/7706/9641/64135/3661/57506 9 Human_parechovirus_2 R-HSA-8863795 Downregulation of ERBB2 signaling 12/474 29/10654 1.3630374769023885e-9 1.2528092287702823e-8 6.837020936773539e-9 7311/2064/1956/10000/3320/7316/207/11140/10193/208/7314/6233 12 Human_parechovirus_2 R-HSA-9607240 FLT3 Signaling 36/474 267/10654 2.2158093145195255e-9 2.0190607288337403e-8 1.1018725084906536e-8 5716/5295/5037/8660/7311/818/5170/2064/4893/1956/1438/5290/2260/4140/1437/3667/1843/8452/3845/5291/7316/369/2264/8315/30849/4296/5289/5894/1439/6714/208/5156/10818/7314/6233/5515 36 Human_parechovirus_2 R-HSA-1643713 Signaling by EGFR in Cancer 11/474 25/10654 3.0506782092713463e-9 2.7560400574357376e-8 1.5040680689884823e-8 5295/7311/4893/1956/5290/3320/3845/7316/11140/7314/6233 11 Human_parechovirus_2 R-HSA-69231 Cyclin D associated events in G1 14/474 44/10654 3.3114704766503727e-9 2.941364952789449e-8 1.6052063876199952e-8 8454/6500/1030/7311/894/1019/1021/1874/7316/1029/6714/7314/6233/5515 14 Human_parechovirus_2 R-HSA-69236 G1 Phase 14/474 44/10654 3.3114704766503727e-9 2.941364952789449e-8 1.6052063876199952e-8 8454/6500/1030/7311/894/1019/1021/1874/7316/1029/6714/7314/6233/5515 14 Human_parechovirus_2 R-HSA-2428928 IRS-related events triggered by IGF1R 15/474 52/10654 4.169585199165372e-9 3.6727096295981654e-8 2.004326920300547e-8 5295/8660/5170/4893/5290/2260/3667/3845/5291/8471/2264/30849/5289/208/10818 15 Human_parechovirus_2 R-HSA-9009391 Extra-nuclear estrogen signaling 18/474 77/10654 4.84598487608704e-9 4.233228110763638e-8 2.3102215851202245e-8 5295/3315/7514/5170/596/5590/4893/1956/5290/10000/3320/3845/2100/2309/8877/207/6714/208 18 Human_parechovirus_2 R-HSA-5628897 TP53 Regulates Metabolic Genes 19/474 86/10654 4.968935606271047e-9 4.305053226088932e-8 2.3494190787200468e-8 2475/51422/7249/5563/5571/5562/53632/10000/5728/6009/5564/5565/7157/57521/7248/207/8626/54205/208 19 Human_parechovirus_2 R-HSA-205043 NRIF signals cell death from the nucleus 9/474 16/10654 5.486496760777728e-9 4.714818761091105e-8 2.5730425544768465e-8 7311/4804/5599/7316/4803/7189/8878/7314/6233 9 Human_parechovirus_2 R-HSA-2428924 IGF1R signaling cascade 15/474 53/10654 5.581061178497428e-9 4.757404569090146e-8 2.5962831288765626e-8 5295/8660/5170/4893/5290/2260/3667/3845/5291/8471/2264/30849/5289/208/10818 15 Human_parechovirus_2 R-HSA-5218921 VEGFR2 mediated cell proliferation 10/474 21/10654 6.273279509567651e-9 5.304685153290405e-8 2.8949534073625875e-8 5170/3708/5590/4893/3845/5579/8877/5578/6714/5580 10 Human_parechovirus_2 R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 15/474 54/10654 7.416168745191517e-9 6.076659196641422e-8 3.3162468154752774e-8 5295/8660/5170/4893/5290/2260/3667/3845/5291/8471/2264/30849/5289/208/10818 15 Human_parechovirus_2 R-HSA-74751 Insulin receptor signalling cascade 15/474 54/10654 7.416168745191517e-9 6.076659196641422e-8 3.3162468154752774e-8 5295/8660/5170/4893/5290/2260/3667/3845/5291/2264/3630/30849/5289/208/10818 15 Human_parechovirus_2 R-HSA-8848021 Signaling by PTK6 15/474 54/10654 7.416168745191517e-9 6.076659196641422e-8 3.3162468154752774e-8 7311/3091/2064/2034/1019/4893/387/1956/3845/7316/6774/207/55620/7314/6233 15 Human_parechovirus_2 R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 15/474 54/10654 7.416168745191517e-9 6.076659196641422e-8 3.3162468154752774e-8 7311/3091/2064/2034/1019/4893/387/1956/3845/7316/6774/207/55620/7314/6233 15 Human_parechovirus_2 R-HSA-389356 CD28 co-stimulation 12/474 33/10654 7.917075622765314e-9 6.437191487125336e-8 3.513001976741208e-8 2475/5295/5170/1326/5290/10000/9020/207/6714/208/253260/7525 12 Human_parechovirus_2 R-HSA-5683057 MAPK family signaling cascades 37/474 294/10654 8.9237271514801e-9 7.200289770316387e-8 3.929451570117393e-8 5716/3315/5037/8660/7514/2308/7311/818/3725/2064/4893/1956/1438/2260/4140/1437/3667/1843/8452/3845/2309/7316/369/2264/8315/4296/8202/3569/5597/5894/1439/6714/5156/10818/7314/6233/5515 37 Human_parechovirus_2 R-HSA-5675221 Negative regulation of MAPK pathway 13/474 40/10654 9.084951261457864e-9 7.27484354800073e-8 3.9701381908125276e-8 5037/7311/4893/4140/1843/3845/7316/369/8315/5894/7314/6233/5515 13 Human_parechovirus_2 R-HSA-6807070 PTEN Regulation 24/474 140/10654 1.0631881653137984e-8 8.449548050651767e-8 4.611215786244255e-8 2475/5716/7311/1460/3725/1386/331/10000/7316/5728/5468/6009/1822/7157/57521/8658/207/8975/4734/6045/5987/208/7314/6233 24 Human_parechovirus_2 R-HSA-389357 CD28 dependent PI3K/Akt signaling 10/474 22/10654 1.1046579160171741e-8 8.649062349852986e-8 4.7200977620071074e-8 2475/5295/5170/1326/5290/10000/9020/207/208/253260 10 Human_parechovirus_2 R-HSA-5205685 Pink/Parkin Mediated Mitophagy 10/474 22/10654 1.1046579160171741e-8 8.649062349852986e-8 4.7200977620071074e-8 7311/84557/9474/7316/65018/9140/81631/8878/7314/6233 10 Human_parechovirus_2 R-HSA-112399 IRS-mediated signalling 14/474 48/10654 1.1790727356877497e-8 9.163822658984937e-8 5.001020581709651e-8 5295/8660/5170/4893/5290/2260/3667/3845/5291/2264/30849/5289/208/10818 14 Human_parechovirus_2 R-HSA-166520 Signaling by NTRKs 20/474 101/10654 1.4532755690462773e-8 1.1212498368481131e-7 6.119055027563274e-8 5295/8660/1432/1213/4893/387/5290/4914/3667/3845/5291/6195/4803/6774/9261/6714/10818/5515/7867/5607 20 Human_parechovirus_2 R-HSA-1236974 ER-Phagosome pathway 18/474 83/10654 1.727919173761188e-8 1.3188718217974623e-7 7.197547760245077e-8 5716/23643/1147/8773/7311/10333/7099/8517/4615/929/114609/7316/7097/3551/7096/695/7314/6233 18 Human_parechovirus_2 R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 20/474 102/10654 1.7343725944167196e-8 1.3188718217974623e-7 7.197547760245077e-8 5716/8454/6500/7124/1147/330/7311/7132/8945/329/7187/23291/7186/958/7316/9020/356/4791/7314/6233 20 Human_parechovirus_2 R-HSA-933541 TRAF6 mediated IRF7 activation 11/474 29/10654 2.0132873663083714e-8 1.5200319615628204e-7 8.295349449150283e-8 84282/1387/23586/7706/9641/7186/64135/3661/7189/57506/10010 11 Human_parechovirus_2 R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 20/474 103/10654 2.0649543738583464e-8 1.5479835270696966e-7 8.447890980771736e-8 5295/51135/8660/2064/1956/5290/2260/4615/3667/2100/5291/2264/3630/207/3654/7189/6714/5156/10818/5515 20 Human_parechovirus_2 R-HSA-1236394 Signaling by ERBB4 15/474 58/10654 2.1628514900473902e-8 1.6099535387183744e-7 8.78608314711616e-8 5295/7311/23118/4893/1956/5290/3845/7316/11059/83737/4734/10413/6714/7314/6233 15 Human_parechovirus_2 R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 7/474 10/10654 3.528641908527783e-8 2.608233914205501e-7 1.4234050540104712e-7 51422/5563/1432/5571/53632/5564/5565 7 Human_parechovirus_2 R-HSA-8934903 Receptor Mediated Mitophagy 7/474 11/10654 9.33196116964747e-8 6.849918719664845e-7 3.7382417550927004e-7 8408/1460/84557/9474/9140/81631/6714 7 Human_parechovirus_2 R-HSA-5654743 Signaling by FGFR4 12/474 41/10654 1.2724831770293098e-7 9.275963573241245e-7 5.062219825858888e-7 5295/7311/4893/5290/3845/7316/2264/6714/10818/7314/6233/5515 12 Human_parechovirus_2 R-HSA-9614657 FOXO-mediated transcription of cell death genes 8/474 16/10654 1.3595109861526928e-7 9.842487070982167e-7 5.371391639593913e-7 2308/1387/6794/2309/65018/10018/356/4303 8 Human_parechovirus_2 R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 7/474 12/10654 2.1539052117927038e-7 1.5487604141938014e-6 8.452130727263887e-7 355/7161/7159/7157/8795/8626/8797 7 Human_parechovirus_2 R-HSA-8948751 Regulation of PTEN stability and activity 15/474 69/10654 2.6223723426694664e-7 1.8728699771632609e-6 1.0220910695468477e-6 5716/7311/1460/331/10000/7316/5728/8658/207/8975/4734/5987/208/7314/6233 15 Human_parechovirus_2 R-HSA-1236975 Antigen processing-Cross presentation 18/474 99/10654 3.0022991415444914e-7 2.1052311493217412e-6 1.1488987400570775e-6 5716/23643/1147/8773/7311/10333/7099/8517/4615/929/114609/7316/7097/3551/7096/695/7314/6233 18 Human_parechovirus_2 R-HSA-109704 PI3K Cascade 12/474 44/10654 3.0074730704596304e-7 2.1052311493217412e-6 1.1488987400570775e-6 5295/8660/5170/5290/2260/3667/5291/2264/30849/5289/208/10818 12 Human_parechovirus_2 R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 12/474 44/10654 3.0074730704596304e-7 2.1052311493217412e-6 1.1488987400570775e-6 355/7161/1387/843/332/7159/7157/10397/8795/665/8626/8797 12 Human_parechovirus_2 R-HSA-111465 Apoptotic cleavage of cellular proteins 11/474 38/10654 4.863863275837262e-7 3.3601983546143697e-6 1.8337785174811279e-6 4000/6093/329/841/999/5588/836/51765/1499/7082/5580 11 Human_parechovirus_2 R-HSA-5696394 DNA Damage Recognition in GG-NER 11/474 38/10654 4.863863275837262e-7 3.3601983546143697e-6 1.8337785174811279e-6 7311/8533/1642/7316/10987/5886/50813/7314/10445/6233/51138 11 Human_parechovirus_2 R-HSA-170834 Signaling by TGF-beta Receptor Complex 15/474 73/10654 5.708737294113315e-7 3.91826968823232e-6 2.1383376877471614e-6 7514/1030/7311/23327/23645/5590/387/1874/7316/23439/7321/4087/5499/7314/6233 15 Human_parechovirus_2 R-HSA-2559580 Oxidative Stress Induced Senescence 20/474 125/10654 5.760605230800758e-7 3.928361115455743e-6 2.143844934790367e-6 1030/7311/1432/3725/1019/5599/1021/5606/9448/7316/1029/5608/7157/9261/6045/7314/6233/7867/4194/23043 20 Human_parechovirus_2 R-HSA-453279 Mitotic G1-G1/S phases 22/474 149/10654 6.581282478592195e-7 4.459240756328173e-6 2.433564641206831e-6 5716/8454/6500/1030/7311/6119/6118/894/1019/10000/6117/1021/1874/7316/1029/207/6714/208/7314/6233/5515/7298 22 Human_parechovirus_2 R-HSA-5686938 Regulation of TLR by endogenous ligand 8/474 19/10654 7.091261517874799e-7 4.7741805250915045e-6 2.6054383585621123e-6 23643/10333/7099/929/7097/7096/6279/3146 8 Human_parechovirus_2 R-HSA-5673000 RAF activation 10/474 32/10654 7.368949663964172e-7 4.929734047348183e-6 2.6903293909742615e-6 818/4893/4140/3845/369/8315/4296/5894/6714/5515 10 Human_parechovirus_2 R-HSA-9614085 FOXO-mediated transcription 14/474 65/10654 7.429742288884794e-7 4.939143144246054e-6 2.6954642663415208e-6 2308/1387/4287/10000/6794/2309/65018/10018/3630/356/207/4087/208/4303 14 Human_parechovirus_2 R-HSA-5654741 Signaling by FGFR3 11/474 40/10654 8.618449750638779e-7 5.632784933566735e-6 3.0740090062187636e-6 5295/7311/4893/5290/3845/7316/6714/10818/7314/6233/5515 11 Human_parechovirus_2 R-HSA-198323 AKT phosphorylates targets in the cytosol 7/474 14/10654 8.633028942647219e-7 5.632784933566735e-6 3.0740090062187636e-6 7249/1147/10000/842/572/207/208 7 Human_parechovirus_2 R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 7/474 14/10654 8.633028942647219e-7 5.632784933566735e-6 3.0740090062187636e-6 7161/10000/7159/7157/207/8626/208 7 Human_parechovirus_2 R-HSA-2173788 Downregulation of TGF-beta receptor signaling 9/474 26/10654 1.00501535495641e-6 6.517185461281751e-6 3.5566575041402176e-6 7514/7311/23327/23645/7316/4087/5499/7314/6233 9 Human_parechovirus_2 R-HSA-2559585 Oncogene Induced Senescence 10/474 33/10654 1.015643598599647e-6 6.542962945397155e-6 3.57072518456171e-6 1030/7311/1019/1021/7316/1029/7157/7314/6233/4194 10 Human_parechovirus_2 R-HSA-5684996 MAPK1/MAPK3 signaling 30/474 255/10654 1.021370753065781e-6 6.542962945397155e-6 3.57072518456171e-6 5716/5037/8660/7311/818/2064/4893/1956/1438/2260/4140/1437/3667/1843/8452/3845/7316/369/2264/8315/4296/3569/5894/1439/6714/5156/10818/7314/6233/5515 30 Human_parechovirus_2 R-HSA-167044 Signalling to RAS 8/474 20/10654 1.1361139896830478e-6 7.190853216137614e-6 3.924301710345479e-6 1432/4893/4914/3845/4803/9261/6714/7867 8 Human_parechovirus_2 R-HSA-622312 Inflammasomes 8/474 20/10654 1.1361139896830478e-6 7.190853216137614e-6 3.924301710345479e-6 4210/29108/596/598/4790/5970/4791/3326 8 Human_parechovirus_2 R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 18/474 108/10654 1.146826930526413e-6 7.2154527712286825e-6 3.937726553436557e-6 5295/7124/2308/3091/7291/596/598/3576/332/3320/2309/6774/3569/7157/356/4170/207/4582 18 Human_parechovirus_2 R-HSA-5654736 Signaling by FGFR1 12/474 50/10654 1.3566128101227094e-6 8.484850534317774e-6 4.630481594190251e-6 5295/7311/4893/5290/2260/3845/7316/6714/10818/7314/6233/5515 12 Human_parechovirus_2 R-HSA-74752 Signaling by Insulin receptor 15/474 78/10654 1.3966257914964964e-6 8.683726244775275e-6 4.73901506959802e-6 5295/8660/5170/4893/5290/2260/3667/3845/5291/2264/3630/30849/5289/208/10818 15 Human_parechovirus_2 R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 18/474 110/10654 1.5123561669513742e-6 9.348306833143875e-6 5.1017000891926945e-6 1030/51343/7311/3725/1019/3576/3490/4790/1021/7316/6195/1029/7321/6774/3569/5970/7314/6233 18 Human_parechovirus_2 R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 7/474 15/10654 1.5568139787693325e-6 9.457197560684969e-6 5.161125592048363e-6 7311/81030/6737/7316/3661/7314/6233 7 Human_parechovirus_2 R-HSA-5637810 Constitutive Signaling by EGFRvIII 7/474 15/10654 1.5568139787693325e-6 9.457197560684969e-6 5.161125592048363e-6 5295/4893/1956/5290/3320/3845/11140 7 Human_parechovirus_2 R-HSA-5637812 Signaling by EGFRvIII in Cancer 7/474 15/10654 1.5568139787693325e-6 9.457197560684969e-6 5.161125592048363e-6 5295/4893/1956/5290/3320/3845/11140 7 Human_parechovirus_2 R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 13/474 60/10654 1.7239115635726464e-6 1.0412425843978784e-5 5.682427289249987e-6 5716/8454/6500/1147/7311/8945/23291/7316/9020/5970/4791/7314/6233 13 Human_parechovirus_2 R-HSA-5673001 RAF/MAP kinase cascade 29/474 249/10654 1.9063171927622517e-6 1.144873450425966e-5 6.247977402115514e-6 5716/5037/8660/7311/818/2064/4893/1956/1438/2260/4140/1437/3667/1843/8452/3845/7316/369/2264/8315/4296/5894/1439/6714/5156/10818/7314/6233/5515 29 Human_parechovirus_2 R-HSA-388841 Costimulation by the CD28 family 14/474 70/10654 1.918679888512478e-6 1.1457879334224234e-5 6.252968057715361e-6 2475/5295/5170/1326/5290/10000/3115/9020/207/6714/208/253260/7525/5515 14 Human_parechovirus_2 R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 15/474 80/10654 1.954728836421938e-6 1.1607575169089823e-5 6.334662343933898e-6 7311/23586/81929/5610/11274/7706/7334/7316/3661/2316/4734/5495/51191/7314/6233 15 Human_parechovirus_2 R-HSA-8939211 ESR-mediated signaling 27/474 223/10654 2.049907413944504e-6 1.2104760539325927e-5 6.605993900862031e-6 5295/3315/7514/5170/3725/1387/596/5590/1386/4893/1956/5290/10000/3320/3845/2100/2309/8243/9126/8202/8877/207/2288/2289/6714/208/3326 27 Human_parechovirus_2 R-HSA-75153 Apoptotic execution phase 12/474 52/10654 2.1264020121955437e-6 1.248670514939272e-5 6.81443451861496e-6 4000/6093/329/841/999/5588/836/51765/1499/7082/3146/5580 12 Human_parechovirus_2 R-HSA-110312 Translesion synthesis by REV1 7/474 16/10654 2.661929552222486e-6 1.5478176993056736e-5 8.446986000293875e-6 7311/6119/6118/6117/7316/7314/6233 7 Human_parechovirus_2 R-HSA-912631 Regulation of signaling by CBL 8/474 22/10654 2.6651165683408953e-6 1.5478176993056736e-5 8.446986000293875e-6 5295/7311/5290/5291/7316/7314/6233/7525 8 Human_parechovirus_2 R-HSA-1169408 ISG15 antiviral mechanism 14/474 72/10654 2.73389645344584e-6 1.5790866400504115e-5 8.617631616268741e-6 7311/23586/81929/5610/11274/7706/7334/7316/3661/4734/5495/51191/7314/6233 14 Human_parechovirus_2 R-HSA-5655291 Signaling by FGFR4 in disease 6/474 11/10654 2.8693894613233686e-6 1.6394295462804328e-5 8.94694409561995e-6 5295/4893/5290/3845/2264/10818 6 Human_parechovirus_2 R-HSA-9614399 Regulation of localization of FOXO transcription factors 6/474 11/10654 2.8693894613233686e-6 1.6394295462804328e-5 8.94694409561995e-6 2308/10000/2309/207/208/4303 6 Human_parechovirus_2 R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 15/474 84/10654 3.7030716704111444e-6 2.104379976142247e-5 1.148434224892647e-5 7311/6119/6118/8533/1642/6117/7334/7316/10987/5886/50813/7314/10445/6233/51138 15 Human_parechovirus_2 R-HSA-8854214 TBC/RABGAPs 11/474 46/10654 3.903099589700898e-6 2.2061905167453738e-5 1.2039958205213015e-5 7249/8408/11345/338382/5868/9363/7248/81631/7879/11337/51256 11 Human_parechovirus_2 R-HSA-5655862 Translesion synthesis by POLK 7/474 17/10654 4.352492514823286e-6 2.4341717397715417e-5 1.3284131986205296e-5 7311/6119/6118/6117/7316/7314/6233 7 Human_parechovirus_2 R-HSA-5656121 Translesion synthesis by POLI 7/474 17/10654 4.352492514823286e-6 2.4341717397715417e-5 1.3284131986205296e-5 7311/6119/6118/6117/7316/7314/6233 7 Human_parechovirus_2 R-HSA-8878159 Transcriptional regulation by RUNX3 16/474 96/10654 4.51184097430933e-6 2.5100083736026116e-5 1.3697999190700903e-5 5716/7311/8463/1387/3845/2309/7316/1499/2648/10018/1029/7157/10413/6714/7314/6233 16 Human_parechovirus_2 R-HSA-5689877 Josephin domain DUBs 6/474 12/10654 5.523388401467474e-6 3.0407403855995418e-5 1.6594390592128157e-5 7311/4287/7316/5886/7314/6233 6 Human_parechovirus_2 R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 6/474 12/10654 5.523388401467474e-6 3.0407403855995418e-5 1.6594390592128157e-5 5295/8660/23533/5290/5294/5291 6 Human_parechovirus_2 R-HSA-3371571 HSF1-dependent transactivation 8/474 24/10654 5.665010730279118e-6 3.086554815414963e-5 1.684441606181746e-5 2475/818/3303/1387/3320/57521/2288/3326 8 Human_parechovirus_2 R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 8/474 24/10654 5.665010730279118e-6 3.086554815414963e-5 1.684441606181746e-5 1432/5590/5579/30849/5289/6279/5578/5580 8 Human_parechovirus_2 R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 11/474 48/10654 6.098168215165335e-6 3.305519899194748e-5 1.8039385597358186e-5 5295/7311/1438/5290/1437/5291/7316/1439/7314/6233/7525 11 Human_parechovirus_2 R-HSA-2173789 TGF-beta receptor signaling activates SMADs 9/474 32/10654 7.104352969111895e-6 3.786701843696512e-5 2.066536483937349e-5 7514/7311/23327/23645/7316/4087/5499/7314/6233 9 Human_parechovirus_2 R-HSA-397795 G-protein beta:gamma signalling 9/474 32/10654 7.104352969111895e-6 3.786701843696512e-5 2.066536483937349e-5 5170/146850/23533/387/10000/5294/207/695/208 9 Human_parechovirus_2 R-HSA-5656169 Termination of translesion DNA synthesis 9/474 32/10654 7.104352969111895e-6 3.786701843696512e-5 2.066536483937349e-5 7311/6119/6118/7706/6117/7316/9100/7314/6233 9 Human_parechovirus_2 R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 32/474 309/10654 7.129173764386054e-6 3.786701843696512e-5 2.066536483937349e-5 7322/5716/8454/6500/51343/7311/23327/6047/10533/8945/6737/23291/10616/8452/9666/9903/7334/7316/7321/135892/7428/7335/11059/83737/997/4734/10075/9817/10193/51191/7314/6233 32 Human_parechovirus_2 R-HSA-392451 G beta:gamma signalling through PI3Kgamma 8/474 25/10654 8.009081332164054e-6 4.211740780147963e-5 2.2984951924723236e-5 5170/146850/23533/387/10000/5294/207/208 8 Human_parechovirus_2 R-HSA-9006335 Signaling by Erythropoietin 8/474 25/10654 8.009081332164054e-6 4.211740780147963e-5 2.2984951924723236e-5 5295/8660/23533/4893/5290/5294/3845/5291 8 Human_parechovirus_2 R-HSA-5676590 NIK-->noncanonical NF-kB signaling 12/474 59/10654 8.683978537254626e-6 4.5440422345931386e-5 2.4798437928168503e-5 5716/8454/6500/1147/7311/8945/23291/7316/9020/4791/7314/6233 12 Human_parechovirus_2 R-HSA-171007 p38MAPK events 6/474 13/10654 9.87301954765793e-6 5.140779143780508e-5 2.805504128657789e-5 1432/4893/3845/9261/6714/7867 6 Human_parechovirus_2 R-HSA-110320 Translesion Synthesis by POLH 7/474 19/10654 1.043292841307091e-5 5.4056888885372316e-5 2.950074700909628e-5 7311/6119/6118/6117/7316/7314/6233 7 Human_parechovirus_2 R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 10/474 42/10654 1.1252709808378635e-5 5.8020069597347406e-5 3.16635942233196e-5 7514/7311/8945/331/7316/1499/207/208/7314/6233 10 Human_parechovirus_2 R-HSA-187687 Signalling to ERKs 9/474 34/10654 1.2269577510652751e-5 6.295603606194154e-5 3.435732486375937e-5 1432/4893/4914/3845/4803/9261/6714/10818/7867 9 Human_parechovirus_2 R-HSA-6802957 Oncogenic MAPK signaling 13/474 71/10654 1.2388255652055956e-5 6.325790446484611e-5 3.4522065076667504e-5 4000/5037/818/10533/4893/4140/3845/10018/369/8315/4296/5894/6714 13 Human_parechovirus_2 R-HSA-5696395 Formation of Incision Complex in GG-NER 10/474 43/10654 1.4086999782785669e-5 7.158634024232909e-5 3.90671856324218e-5 7311/6119/6118/1642/6117/7334/7316/5886/7314/6233 10 Human_parechovirus_2 R-HSA-8876384 Listeria monocytogenes entry into host cells 7/474 20/10654 1.5438905410279753e-5 7.80809713811756e-5 4.261153444892121e-5 7311/999/7316/1499/6714/7314/6233 7 Human_parechovirus_2 R-HSA-114604 GPVI-mediated activation cascade 9/474 35/10654 1.587327815104107e-5 7.989550002690673e-5 4.360178660035342e-5 5295/5170/146850/5590/23533/387/5290/5294/5291 9 Human_parechovirus_2 R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 6/474 14/10654 1.6630307037702854e-5 8.33091684305778e-5 4.5464745605693015e-5 7161/332/7159/7157/10397/8626 6 Human_parechovirus_2 R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 10/474 44/10654 1.7514797340046617e-5 8.73261357944777e-5 4.765694608910401e-5 1030/7311/23327/1874/7316/23439/7321/4087/7314/6233 10 Human_parechovirus_2 R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 22/474 182/10654 1.8629348041279205e-5 9.244704638324939e-5 5.045160724794171e-5 672/367/1387/81929/7155/8517/332/9641/6117/8243/9126/7022/5468/1029/7428/7157/5970/4792/6045/6790/5987/4791 22 Human_parechovirus_2 R-HSA-5621575 CD209 (DC-SIGN) signaling 7/474 21/10654 2.2276242271912616e-5 1.1002798168883943e-4 6.0046142474216006e-5 3384/1387/4893/4790/3845/5970/5894 7 Human_parechovirus_2 R-HSA-195258 RHO GTPase Effectors 32/474 327/10654 2.2702832652980392e-5 1.1161346099628035e-4 6.091139433945291e-5 7514/6093/57120/5170/367/1432/11130/81929/5590/1072/5347/387/999/6232/332/1780/5579/3895/1499/8655/30849/5289/2316/695/140735/6279/10458/4771/5578/6714/5515/5580 32 Human_parechovirus_2 R-HSA-1234174 Cellular response to hypoxia 13/474 75/10654 2.294142176196543e-5 1.1174692535667031e-4 6.098423053871965e-5 7322/5716/7311/3091/1387/2034/7316/112399/7321/405/7428/7314/6233 13 Human_parechovirus_2 R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 13/474 75/10654 2.294142176196543e-5 1.1174692535667031e-4 6.098423053871965e-5 5295/8660/2064/1956/5290/2260/3667/2100/5291/2264/6714/5156/10818 13 Human_parechovirus_2 R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 14/474 86/10654 2.344503871253269e-5 1.1367617394104154e-4 6.203708939868622e-5 5295/3708/1072/5290/5581/3320/5291/695/10458/4771/6714/7525/3326/5580 14 Human_parechovirus_2 R-HSA-8878166 Transcriptional regulation by RUNX2 17/474 121/10654 2.3974532844092045e-5 1.1571269961737576e-4 6.314849314377526e-5 5716/8454/6500/7311/367/7291/1019/10000/7316/11059/207/10413/6714/208/7314/6233/7525 17 Human_parechovirus_2 R-HSA-844456 The NLRP3 inflammasome 6/474 15/10654 2.667930241032519e-5 1.2818192112597148e-4 6.995338622420194e-5 4210/29108/4790/5970/4791/3326 6 Human_parechovirus_2 R-HSA-190236 Signaling by FGFR 14/474 87/10654 2.6825153678828694e-5 1.2829949067204492e-4 7.00175480638158e-5 5295/7311/4670/4893/5290/2260/3845/7316/2264/6714/10818/7314/6233/5515 14 Human_parechovirus_2 R-HSA-186763 Downstream signal transduction 8/474 29/10654 2.7154956837178393e-5 1.2871205998608772e-4 7.024270166048507e-5 5295/4893/5290/3845/5291/6774/6714/5156 8 Human_parechovirus_2 R-HSA-5218920 VEGFR2 mediated vascular permeability 8/474 29/10654 2.7154956837178393e-5 1.2871205998608772e-4 7.024270166048507e-5 2475/5170/10000/3320/1499/207/208/253260 8 Human_parechovirus_2 R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 14/474 88/10654 3.062608098042133e-5 1.4451681962636317e-4 7.886791530672412e-5 5716/3315/7514/7311/3303/1432/7316/9261/207/5578/7314/6233/1994/5580 14 Human_parechovirus_2 R-HSA-2990846 SUMOylation 22/474 188/10654 3.100208629190062e-5 1.456409120468398e-4 7.948137210742242e-5 672/367/1387/81929/7155/8517/332/9641/6117/8243/9126/7022/5468/1029/7428/7157/5970/4792/6045/6790/5987/4791 22 Human_parechovirus_2 R-HSA-1250196 SHC1 events in ERBB2 signaling 7/474 22/10654 3.142810093357936e-5 1.4634142152772416e-4 7.986366478832129e-5 2064/4893/1956/5581/3845/5578/5580 7 Human_parechovirus_2 R-HSA-9613829 Chaperone Mediated Autophagy 7/474 22/10654 3.142810093357936e-5 1.4634142152772416e-4 7.986366478832129e-5 7311/3920/3320/7316/7314/6233/3326 7 Human_parechovirus_2 R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 10/474 47/10654 3.241723207253002e-5 1.476940271580355e-4 8.060182929104561e-5 8454/6500/7311/3091/1387/7316/2648/55869/7314/6233 10 Human_parechovirus_2 R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 10/474 47/10654 3.241723207253002e-5 1.476940271580355e-4 8.060182929104561e-5 5037/818/4893/4140/3845/369/8315/4296/5894/6714 10 Human_parechovirus_2 R-HSA-6802949 Signaling by RAS mutants 10/474 47/10654 3.241723207253002e-5 1.476940271580355e-4 8.060182929104561e-5 5037/818/4893/4140/3845/369/8315/4296/5894/6714 10 Human_parechovirus_2 R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 10/474 47/10654 3.241723207253002e-5 1.476940271580355e-4 8.060182929104561e-5 5037/818/4893/4140/3845/369/8315/4296/5894/6714 10 Human_parechovirus_2 R-HSA-9649948 Signaling downstream of RAS mutants 10/474 47/10654 3.241723207253002e-5 1.476940271580355e-4 8.060182929104561e-5 5037/818/4893/4140/3845/369/8315/4296/5894/6714 10 Human_parechovirus_2 R-HSA-3371556 Cellular response to heat stress 14/474 89/10654 3.489167638110362e-5 1.5828541602929842e-4 8.638192300359063e-5 2475/6119/818/3303/6118/1387/81929/3309/3320/6117/57521/9261/2288/3326 14 Human_parechovirus_2 R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 8/474 30/10654 3.560258157119919e-5 1.599856203985127e-4 8.730978437323604e-5 7311/6119/6118/1642/6117/7316/7314/6233 8 Human_parechovirus_2 R-HSA-418889 Caspase activation via Dependence Receptors in the absence of ligand 5/474 10/10654 3.572053586948817e-5 1.599856203985127e-4 8.730978437323604e-5 1613/23604/836/1612/842 5 Human_parechovirus_2 R-HSA-8853334 Signaling by FGFR3 fusions in cancer 5/474 10/10654 3.572053586948817e-5 1.599856203985127e-4 8.730978437323604e-5 5295/4893/5290/3845/10818 5 Human_parechovirus_2 R-HSA-73893 DNA Damage Bypass 10/474 48/10654 3.934330150867878e-5 1.754678046188754e-4 9.575895725852086e-5 7311/6119/6118/7706/1642/6117/7316/9100/7314/6233 10 Human_parechovirus_2 R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 9/474 39/10654 4.064612876969591e-5 1.8051663071247303e-4 9.85142793710454e-5 7311/6119/6118/7706/6117/7316/9100/7314/6233 9 Human_parechovirus_2 R-HSA-1295596 Spry regulation of FGF signaling 6/474 16/10654 4.1089726125186847e-5 1.8096600214301042e-4 9.875951717808067e-5 7311/7316/6714/7314/6233/5515 6 Human_parechovirus_2 R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 6/474 16/10654 4.1089726125186847e-5 1.8096600214301042e-4 9.875951717808067e-5 7311/5590/387/7316/7314/6233 6 Human_parechovirus_2 R-HSA-9006936 Signaling by TGF-beta family members 15/474 102/10654 4.175545581704914e-5 1.8313492447560558e-4 9.99431744387112e-5 7514/1030/7311/23327/23645/5590/387/1874/7316/23439/7321/4087/5499/7314/6233 15 Human_parechovirus_2 R-HSA-8951664 Neddylation 25/474 234/10654 4.3042625944237176e-5 1.8800022984735e-4 1.0259834283358842e-4 7322/5716/8454/6500/7311/3091/8945/2034/23291/8533/332/149951/1642/8452/8835/9903/7316/7321/10987/7428/50813/9817/7314/6233/51138 25 Human_parechovirus_2 R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 7/474 23/10654 4.3459175475695984e-5 1.8903847110210146e-4 1.031649476312818e-4 7311/23327/7316/7321/4087/7314/6233 7 Human_parechovirus_2 R-HSA-5654733 Negative regulation of FGFR4 signaling 8/474 31/10654 4.613791241132144e-5 1.9986792384740475e-4 1.0907496117948296e-4 7311/7316/2264/6714/10818/7314/6233/5515 8 Human_parechovirus_2 R-HSA-177929 Signaling by EGFR 10/474 49/10654 4.749476250711735e-5 2.0490597538784915e-4 1.1182440323909909e-4 5295/7311/4893/1956/5290/3845/7316/6714/7314/6233 10 Human_parechovirus_2 R-HSA-6783310 Fanconi Anemia Pathway 9/474 40/10654 5.0407602607733096e-5 2.1658876405030033e-4 1.1820011223379435e-4 7311/6119/6118/2189/6117/2175/7316/7314/6233 9 Human_parechovirus_2 R-HSA-438064 Post NMDA receptor activation events 13/474 81/10654 5.331581070240618e-5 2.2815713324875843e-4 1.2451337849954652e-4 51422/818/5170/5563/5571/5562/53632/4893/3845/6195/5564/5565/6714 13 Human_parechovirus_2 R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 7/474 24/10654 5.9021478606161704e-5 2.51086737063876e-4 1.370268703988488e-4 7514/596/1956/10000/2309/207/208 7 Human_parechovirus_2 R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 8/474 32/10654 5.914909889205782e-5 2.51086737063876e-4 1.370268703988488e-4 1030/7311/1874/7316/23439/4087/7314/6233 8 Human_parechovirus_2 R-HSA-9034015 Signaling by NTRK3 (TRKC) 6/474 17/10654 6.112821718538525e-5 2.584501022598088e-4 1.4104531796880473e-4 5295/4893/5290/3667/3845/6714 6 Human_parechovirus_2 R-HSA-4755510 SUMOylation of immune response proteins 5/474 11/10654 6.309649120962545e-5 2.6570912832101233e-4 1.4500682400031347e-4 8517/9641/5970/4792/4791 5 Human_parechovirus_2 R-HSA-69206 G1/S Transition 17/474 131/10654 6.738983164022125e-5 2.826629049353725e-4 1.5425909665347221e-4 5716/8454/6500/7311/6119/6118/1019/10000/6117/1874/7316/207/208/7314/6233/5515/7298 17 Human_parechovirus_2 R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 12/474 72/10654 7.043681698279632e-5 2.94275555536821e-4 1.60596528839494e-4 51422/8773/5563/5571/53632/5564/60412/5565/207/149371/208/55770 12 Human_parechovirus_2 R-HSA-5654726 Negative regulation of FGFR1 signaling 8/474 33/10654 7.507277246293932e-5 3.124091358004994e-4 1.7049266187190533e-4 7311/2260/7316/6714/10818/7314/6233/5515 8 Human_parechovirus_2 R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 7/474 25/10654 7.885963310160528e-5 3.268809105427325e-4 1.7839041873964786e-4 7311/6119/6118/6117/7316/7314/6233 7 Human_parechovirus_2 R-HSA-5654738 Signaling by FGFR2 12/474 73/10654 8.09574447606112e-5 3.342656996561173e-4 1.8242055809545617e-4 5295/7311/4670/4893/5290/3845/7316/6714/10818/7314/6233/5515 12 Human_parechovirus_2 R-HSA-111471 Apoptotic factor-mediated response 6/474 18/10654 8.826708830388397e-5 3.616213656480828e-4 1.9734950791729263e-4 836/331/1029/842/54205/578 6 Human_parechovirus_2 R-HSA-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 6/474 18/10654 8.826708830388397e-5 3.616213656480828e-4 1.9734950791729263e-4 330/329/7187/7186/958/9020 6 Human_parechovirus_2 R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 13/474 85/10654 8.921805521756594e-5 3.641061172392556e-4 1.9870552432117922e-4 5716/8454/6500/51343/7311/1019/10000/1874/7316/207/208/7314/6233 13 Human_parechovirus_2 R-HSA-69242 S Phase 19/474 161/10654 9.518061316024173e-5 3.869458004245212e-4 2.1116994336766183e-4 5716/8454/6500/51343/7311/6119/6118/1019/10000/6117/1874/8243/9126/7316/7321/207/208/7314/6233 19 Human_parechovirus_2 R-HSA-1660499 Synthesis of PIPs at the plasma membrane 10/474 53/10654 9.60595283240743e-5 3.890226875040097e-4 2.1230337375113017e-4 5295/146850/23533/5290/5294/5291/5728/5868/5286/5287 10 Human_parechovirus_2 R-HSA-3371511 HSF1 activation 5/474 12/10654 1.0422013607259564e-4 4.2046062530050993e-4 2.2946016298827808e-4 6119/6118/3320/6117/3326 5 Human_parechovirus_2 R-HSA-5696398 Nucleotide Excision Repair 15/474 111/10654 1.1269424425346213e-4 4.529194531403402e-4 2.4717408785630276e-4 7311/6119/6118/8533/1642/6117/7334/7316/10987/5886/50813/7314/10445/6233/51138 15 Human_parechovirus_2 R-HSA-9007101 Rab regulation of trafficking 16/474 124/10654 1.1751238486439111e-4 4.7049466212750534e-4 2.5676549802905235e-4 7249/8408/83696/11345/338382/10000/5868/9363/7248/81631/207/7879/11337/51256/208/9367 16 Human_parechovirus_2 R-HSA-204998 Cell death signalling via NRAGE, NRIF and NADE 12/474 76/10654 1.2102413607307194e-4 4.8272645973296995e-4 2.634408205284744e-4 7311/4804/836/5599/7316/4803/10018/572/7189/8878/7314/6233 12 Human_parechovirus_2 R-HSA-6804760 Regulation of TP53 Activity through Methylation 6/474 19/10654 1.2419054671502814e-4 4.934940145781381e-4 2.693170542138323e-4 7311/7316/7157/7314/6233/4194 6 Human_parechovirus_2 R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 11/474 66/10654 1.4052030789558196e-4 5.562920054143451e-4 3.0358812823488634e-4 7322/5716/7311/3091/2034/7316/112399/7321/7428/7314/6233 11 Human_parechovirus_2 R-HSA-6802952 Signaling by BRAF and RAF fusions 11/474 67/10654 1.6151251055757999e-4 6.370101629080673e-4 3.476388679715391e-4 4000/5037/818/10533/4893/4140/3845/10018/369/5894/6714 11 Human_parechovirus_2 R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 6/474 20/10654 1.7079839298849193e-4 6.711297449399107e-4 3.662591248589066e-4 7161/1387/7159/7157/665/8626 6 Human_parechovirus_2 R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 12/474 79/10654 1.7701782167298016e-4 6.929919907716298e-4 3.781901219368154e-4 7311/6119/6118/8533/1642/6117/7316/10987/50813/7314/6233/51138 12 Human_parechovirus_2 R-HSA-73894 DNA Repair 30/474 334/10654 1.9413943013951184e-4 7.572154157101992e-4 4.13239105521276e-4 672/7311/6119/6118/7013/5531/6047/9025/2189/25913/7706/8533/151987/1642/6117/2175/5599/5591/7334/7316/328/10987/7157/5886/50813/9100/7314/10445/6233/51138 30 Human_parechovirus_2 R-HSA-5654732 Negative regulation of FGFR3 signaling 7/474 29/10654 2.19351986385298e-4 8.492858960046153e-4 4.6348520739982e-4 7311/7316/6714/10818/7314/6233/5515 7 Human_parechovirus_2 R-HSA-9619483 Activation of AMPK downstream of NMDARs 7/474 29/10654 2.19351986385298e-4 8.492858960046153e-4 4.6348520739982e-4 51422/5563/5571/5562/53632/5564/5565 7 Human_parechovirus_2 R-HSA-442755 Activation of NMDA receptors and postsynaptic events 13/474 93/10654 2.267030522368594e-4 8.745442562567897e-4 4.7726958365654616e-4 51422/818/5170/5563/5571/5562/53632/4893/3845/6195/5564/5565/6714 13 Human_parechovirus_2 R-HSA-389513 CTLA4 inhibitory signaling 6/474 21/10654 2.302072532751235e-4 8.84832969861111e-4 4.828844968220773e-4 10000/207/6714/208/7525/5515 6 Human_parechovirus_2 R-HSA-400253 Circadian Clock 11/474 70/10654 2.4114745097474644e-4 9.235248394214021e-4 5.040000119533221e-4 8454/6500/7311/3091/8945/1387/1386/7316/5499/7314/6233 11 Human_parechovirus_2 R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 10/474 59/10654 2.4368676770168985e-4 9.298805540096974e-4 5.074685491184725e-4 7322/7311/5591/7334/7316/7321/79139/8915/7314/6233 10 Human_parechovirus_2 R-HSA-3371568 Attenuation phase 5/474 14/10654 2.4460751549122494e-4 9.300364887562041e-4 5.075536481983767e-4 3303/1387/3320/2288/3326 5 Human_parechovirus_2 R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 7/474 30/10654 2.7527571828524173e-4 0.0010428904452598584 5.691420246003112e-4 7322/7311/7316/7321/997/7314/6233 7 Human_parechovirus_2 R-HSA-5610780 Degradation of GLI1 by the proteasome 10/474 60/10654 2.810142375236614e-4 0.0010608287466518217 5.789315870788213e-4 5716/8454/6500/7311/8945/2735/7316/83737/7314/6233 10 Human_parechovirus_2 R-HSA-69202 Cyclin E associated events during G1/S transition 12/474 83/10654 2.849655968655131e-4 0.0010719168536898482 5.849827573789144e-4 5716/8454/6500/7311/1019/10000/1874/7316/207/208/7314/6233 12 Human_parechovirus_2 R-HSA-1483255 PI Metabolism 12/474 84/10654 3.1934321815981387e-4 0.001196970856719586 6.532291285986488e-4 5295/146850/23533/5290/5294/5291/5728/5868/30849/5286/5289/5287 12 Human_parechovirus_2 R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 7/474 31/10654 3.421075783318007e-4 0.0012777657607657715 6.973217516303767e-4 1432/3725/1386/5599/6195/9261/5515 7 Human_parechovirus_2 R-HSA-1980143 Signaling by NOTCH1 11/474 73/10654 3.5168311086911916e-4 0.0013089050992558414 7.143155847156313e-4 8454/6500/7311/3091/1387/7316/2648/55869/83737/7314/6233 11 Human_parechovirus_2 R-HSA-111447 Activation of BAD and translocation to mitochondria 5/474 15/10654 3.5357162203167466e-4 0.0013113165069736144 7.156315747861782e-4 596/10000/572/207/208 5 Human_parechovirus_2 R-HSA-9006931 Signaling by Nuclear Receptors 27/474 299/10654 3.697276233294753e-4 0.001366440901605788 7.45714897256358e-4 5295/3315/7514/5170/3725/1387/596/5590/1386/4893/1956/5290/10000/3320/3845/2100/2309/8243/9126/8202/8877/207/2288/2289/6714/208/3326 27 Human_parechovirus_2 R-HSA-5696400 Dual Incision in GG-NER 8/474 41/10654 3.777454086371179e-4 0.0013912087001025561 7.592315566959128e-4 7311/6119/6118/1642/6117/7316/7314/6233 8 Human_parechovirus_2 R-HSA-5693607 Processing of DNA double-strand break ends 13/474 98/10654 3.83444879077342e-4 0.0014072959624470503 7.680109420116353e-4 672/7311/6119/6118/5531/6047/9025/151987/6117/7334/7316/7314/6233 13 Human_parechovirus_2 R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 12/474 86/10654 3.987245991888828e-4 0.001453282418422928 7.931073697114621e-4 5716/8454/6500/51343/7311/8945/5347/7316/7321/6790/7314/6233 12 Human_parechovirus_2 R-HSA-453276 Regulation of mitotic cell cycle 12/474 86/10654 3.987245991888828e-4 0.001453282418422928 7.931073697114621e-4 5716/8454/6500/51343/7311/8945/5347/7316/7321/6790/7314/6233 12 Human_parechovirus_2 R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 12/474 88/10654 4.941669318898628e-4 0.0017949637354212542 9.795748912123162e-4 8454/6500/7311/8945/5347/23291/3320/7316/8655/6790/7314/6233 12 Human_parechovirus_2 R-HSA-1433557 Signaling by SCF-KIT 8/474 43/10654 5.30234341242998e-4 0.0019193756804583868 0.0010474708687857352 5295/4893/5290/3845/6774/5578/6714/7525 8 Human_parechovirus_2 R-HSA-5687128 MAPK6/MAPK4 signaling 12/474 89/10654 5.486782514070547e-4 0.001979361473505996 0.0010802072274872139 5716/3315/7514/2308/7311/3725/2309/7316/8202/5597/7314/6233 12 Human_parechovirus_2 R-HSA-913531 Interferon Signaling 20/474 199/10654 5.519626265176055e-4 0.0019844370620037723 0.0010829771547857063 7311/818/23586/81929/5610/11274/6737/7706/3115/7334/7316/10410/3661/2316/4734/5495/51191/7314/6233/5580 20 Human_parechovirus_2 R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 9/474 54/10654 5.637483212000711e-4 0.0020199389000287293 0.0011023517574224406 7311/8533/1642/7316/10987/50813/7314/6233/51138 9 Human_parechovirus_2 R-HSA-5654727 Negative regulation of FGFR2 signaling 7/474 34/10654 6.234920162924613e-4 0.0022264562879092285 0.0012150555651787654 7311/7316/6714/10818/7314/6233/5515 7 Human_parechovirus_2 R-HSA-68882 Mitotic Anaphase 20/474 201/10654 6.273125117016202e-4 0.0022325566493892677 0.0012183847471645862 5716/4000/7514/7311/11130/81929/5347/6232/332/1780/8243/9126/7316/55869/7321/8655/140735/7314/6233/5515 20 Human_parechovirus_2 R-HSA-76002 Platelet activation, signaling and aggregation 24/474 262/10654 6.305574383489858e-4 0.0022365745380365032 0.0012205774504247412 5295/5170/146850/1432/3920/3708/5590/23533/1072/387/5588/5290/5581/3309/5294/5579/5291/308/2316/5894/207/5578/6714/5580 24 Human_parechovirus_2 R-HSA-2029485 Role of phospholipids in phagocytosis 6/474 25/10654 6.456481114605148e-4 0.002268059323569606 0.001237759806120743 5295/3708/5290/5581/5291/5580 6 Human_parechovirus_2 R-HSA-9006115 Signaling by NTRK2 (TRKB) 6/474 25/10654 6.456481114605148e-4 0.002268059323569606 0.001237759806120743 5295/4893/5290/3845/6714/10818 6 Human_parechovirus_2 R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 9/474 55/10654 6.480169495913159e-4 0.002268059323569606 0.001237759806120743 5716/8454/6500/51343/7311/8945/7316/7314/6233 9 Human_parechovirus_2 R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 9/474 55/10654 6.480169495913159e-4 0.002268059323569606 0.001237759806120743 3303/367/3320/1780/8655/140735/2288/2289/3326 9 Human_parechovirus_2 R-HSA-450341 Activation of the AP-1 family of transcription factors 4/474 10/10654 6.55698554253363e-4 0.002279846617913831 0.00124419254754447 1432/3725/1386/5599 4 Human_parechovirus_2 R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 4/474 10/10654 6.55698554253363e-4 0.002279846617913831 0.00124419254754447 2308/1387/2309/4303 4 Human_parechovirus_2 R-HSA-2555396 Mitotic Metaphase and Anaphase 20/474 202/10654 6.682160267505253e-4 0.0023157519353288695 0.0012637873430864123 5716/4000/7514/7311/11130/81929/5347/6232/332/1780/8243/9126/7316/55869/7321/8655/140735/7314/6233/5515 20 Human_parechovirus_2 R-HSA-6806834 Signaling by MET 11/474 79/10654 7.026312783838631e-4 0.0024191572027744083 0.0013202192372856402 5295/7311/4893/5290/3845/7316/6774/6714/7314/6233/3910 11 Human_parechovirus_2 R-HSA-8852135 Protein ubiquitination 11/474 79/10654 7.026312783838631e-4 0.0024191572027744083 0.0013202192372856402 7322/7311/5591/7334/7316/7321/79139/997/8915/7314/6233 11 Human_parechovirus_2 R-HSA-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle 7/474 35/10654 7.499492526759394e-4 0.0025736894807742465 0.0014045529407601327 7311/51009/7316/79139/7314/6233/821 7 Human_parechovirus_2 R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 11/474 80/10654 7.827560408011948e-4 0.002677582961575608 0.0014612512701722188 5716/8454/6500/51343/7311/8945/5347/7316/7321/7314/6233 11 Human_parechovirus_2 R-HSA-2467813 Separation of Sister Chromatids 19/474 190/10654 8.008657032061441e-4 0.0027306937041577236 0.0014902356718402955 5716/7514/7311/11130/81929/5347/6232/332/1780/8243/9126/7316/55869/7321/8655/140735/7314/6233/5515 19 Human_parechovirus_2 R-HSA-901042 Calnexin/calreticulin cycle 6/474 26/10654 8.081978638907993e-4 0.002746833254445578 0.001499043592527189 7311/51009/7316/7314/6233/821 6 Human_parechovirus_2 R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 7/474 36/10654 8.958581317891023e-4 0.003035006555452183 0.001656309906276748 5037/4893/4140/3845/369/5894/6714 7 Human_parechovirus_2 R-HSA-210993 Tie2 Signaling 5/474 18/10654 9.029406568773037e-4 0.0030395167971952546 0.0016587713039516007 5295/4893/5290/3845/5291 5 Human_parechovirus_2 R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 5/474 18/10654 9.029406568773037e-4 0.0030395167971952546 0.0016587713039516007 4893/1956/3845/6195/5578 5 Human_parechovirus_2 R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 9/474 58/10654 9.644532024816982e-4 0.0031956960345553447 0.0017440038111201804 8454/6500/7311/1387/7316/2648/55869/7314/6233 9 Human_parechovirus_2 R-HSA-2644603 Signaling by NOTCH1 in Cancer 9/474 58/10654 9.644532024816982e-4 0.0031956960345553447 0.0017440038111201804 8454/6500/7311/1387/7316/2648/55869/7314/6233 9 Human_parechovirus_2 R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 9/474 58/10654 9.644532024816982e-4 0.0031956960345553447 0.0017440038111201804 8454/6500/7311/1387/7316/2648/55869/7314/6233 9 Human_parechovirus_2 R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 9/474 58/10654 9.644532024816982e-4 0.0031956960345553447 0.0017440038111201804 8454/6500/7311/1387/7316/2648/55869/7314/6233 9 Human_parechovirus_2 R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 9/474 58/10654 9.644532024816982e-4 0.0031956960345553447 0.0017440038111201804 8454/6500/7311/1387/7316/2648/55869/7314/6233 9 Human_parechovirus_2 R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 4/474 11/10654 9.943283045640706e-4 0.0032639907388951014 0.001781274635178525 3091/1387/2034/405 4 Human_parechovirus_2 R-HSA-193692 Regulated proteolysis of p75NTR 4/474 11/10654 9.943283045640706e-4 0.0032639907388951014 0.001781274635178525 4804/4790/5970/7189 4 Human_parechovirus_2 R-HSA-351906 Apoptotic cleavage of cell adhesion proteins 4/474 11/10654 9.943283045640706e-4 0.0032639907388951014 0.001781274635178525 999/836/1499/7082 4 Human_parechovirus_2 R-HSA-5654716 Downstream signaling of activated FGFR4 6/474 27/10654 0.0010005878785958099 0.00326426354220917 0.0017814235135493954 5295/4893/5290/3845/2264/10818 6 Human_parechovirus_2 R-HSA-912526 Interleukin receptor SHC signaling 6/474 27/10654 0.0010005878785958099 0.00326426354220917 0.0017814235135493954 5295/1438/5290/1437/5291/1439 6 Human_parechovirus_2 R-HSA-202733 Cell surface interactions at the vascular wall 15/474 137/10654 0.0011172228757773395 0.0036335525529127624 0.0019829575252663387 5295/4893/5290/3845/482/5291/8795/481/2994/483/5669/6714/4099/7525/8797 15 Human_parechovirus_2 R-HSA-5655302 Signaling by FGFR1 in disease 7/474 38/10654 0.0012542479472163561 0.004066687362600271 0.002219334436792261 5295/4893/5290/2260/3845/6774/10818 7 Human_parechovirus_2 R-HSA-69620 Cell Cycle Checkpoints 25/474 293/10654 0.001363338924452285 0.004406878419406928 0.0024049886708509653 5716/672/7514/7311/6119/6118/9025/11130/81929/5347/6232/332/1780/6117/7334/7316/1029/7321/8655/7157/140735/7314/6233/5515/4194 25 Human_parechovirus_2 R-HSA-8943724 Regulation of PTEN gene transcription 9/474 61/10654 0.0013960042608517208 0.004498708852805698 0.0024551037706891624 2475/3725/1386/5468/6009/1822/7157/57521/6045 9 Human_parechovirus_2 R-HSA-430116 GP1b-IX-V activation signalling 4/474 12/10654 0.0014393823888098115 0.004610385409005972 0.0025160495983023185 5295/2316/5894/6714 4 Human_parechovirus_2 R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 4/474 12/10654 0.0014393823888098115 0.004610385409005972 0.0025160495983023185 7161/843/7157/8626 4 Human_parechovirus_2 R-HSA-162588 Budding and maturation of HIV virion 6/474 29/10654 0.0014889879937290903 0.004740543100517014 0.0025870812319706456 7311/23327/7316/51534/7314/6233 6 Human_parechovirus_2 R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 6/474 29/10654 0.0014889879937290903 0.004740543100517014 0.0025870812319706456 2308/4287/2309/3630/4087/4303 6 Human_parvovirus R-HSA-156842 Eukaryotic Translation Elongation 73/1519 93/10654 2.2762863585685483e-44 3.002421706951915e-41 1.8473860867961588e-41 6158/6138/6144/6203/4736/6206/6194/6191/6166/6128/6132/1917/1938/6147/6129/1915/6217/1936/6176/6136/6125/1937/6224/6146/6154/6141/6202/6134/6169/6160/6164/6155/6175/6218/6209/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133/6230 73 Human_parvovirus R-HSA-156902 Peptide chain elongation 70/1519 89/10654 1.0903898751157984e-42 4.79408081759246e-40 2.949791556892213e-40 6158/6138/6144/6203/4736/6206/6194/6191/6166/6128/6132/1938/6147/6129/1915/6217/6176/6136/6125/6224/6146/6154/6141/6202/6134/6169/6160/6164/6155/6175/6218/6209/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133/6230 70 Human_parvovirus R-HSA-192823 Viral mRNA Translation 70/1519 89/10654 1.0903898751157984e-42 4.79408081759246e-40 2.949791556892213e-40 6158/6138/6144/6203/4736/2926/6206/6194/6191/6166/6128/6132/6147/6129/6217/6176/6136/6125/6224/6146/6154/6141/6202/6134/6169/6160/6164/6155/6175/6218/5611/6209/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133/6230 70 Human_parvovirus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 72/1519 95/10654 6.600353657462803e-42 2.1764666185483592e-39 1.3391770183957426e-39 6158/6138/6144/6203/4736/6206/6194/6191/6166/6128/6132/6147/6129/6217/6176/6136/6125/6224/6146/6154/6141/26986/6202/2935/6134/6169/6160/6164/6155/6175/6218/6209/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/1981/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/5976/6187/6168/6208/6157/6137/6122/6133/6230 72 Human_parvovirus R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 78/1519 111/10654 2.7871993765265765e-41 6.641972927194883e-39 4.0867971165294725e-39 6158/6138/6144/6203/4736/6206/6194/6191/6166/6128/6132/6147/6129/6217/6176/6136/6125/6224/6146/6154/6141/10480/26986/6202/6134/6169/6160/6164/6155/6175/6218/6209/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/8894/1981/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/1974/6122/6133/1968/6230 78 Human_parvovirus R-HSA-72613 Eukaryotic Translation Initiation 81/1519 119/10654 3.5249287710662763e-41 6.641972927194883e-39 4.0867971165294725e-39 6158/6138/6144/6203/4736/6206/6194/6191/6166/6128/6132/6147/6129/6217/6176/6136/6125/6224/6146/6154/6141/10480/26986/6202/6134/6169/6160/6164/6155/6175/6218/6209/6210/6229/6231/11224/6205/6165/6130/8890/6142/6167/6204/6228/23521/8894/1981/6156/6235/6143/1973/6181/6124/6207/1977/6139/8893/6233/1975/7311/6223/25873/8664/3921/6188/6189/6135/6201/1978/6161/9045/6187/6168/6208/6157/6137/1974/6122/6133/1968/6230 81 Human_parvovirus R-HSA-72737 Cap-dependent Translation Initiation 81/1519 119/10654 3.5249287710662763e-41 6.641972927194883e-39 4.0867971165294725e-39 6158/6138/6144/6203/4736/6206/6194/6191/6166/6128/6132/6147/6129/6217/6176/6136/6125/6224/6146/6154/6141/10480/26986/6202/6134/6169/6160/6164/6155/6175/6218/6209/6210/6229/6231/11224/6205/6165/6130/8890/6142/6167/6204/6228/23521/8894/1981/6156/6235/6143/1973/6181/6124/6207/1977/6139/8893/6233/1975/7311/6223/25873/8664/3921/6188/6189/6135/6201/1978/6161/9045/6187/6168/6208/6157/6137/1974/6122/6133/1968/6230 81 Human_parvovirus R-HSA-168254 Influenza Infection 93/1519 155/10654 3.168596404316878e-40 5.224223321617452e-38 3.21445766806357e-38 6158/23165/3303/6138/4928/6144/3838/6203/4736/2926/6206/6194/6191/6166/6128/6132/9631/6147/6129/6217/6176/6136/8106/6125/821/811/6224/6146/6154/6141/9636/6202/57122/5441/6134/6169/5431/6160/23511/6164/6155/6175/293/6218/5611/6209/6210/4927/6229/6231/11224/6205/6165/6130/2962/6142/6167/6204/9883/6228/23521/3320/6156/6235/6143/6181/6124/6207/6139/6233/7514/7311/6223/25873/5610/1211/3921/6188/6189/7040/6135/6201/6161/3304/9045/6187/6168/6208/6157/6137/6122/6133/6230 93 Human_parvovirus R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 77/1519 112/10654 1.1208220235583245e-39 1.642626943414922e-37 1.0107061756297875e-37 6158/6138/6144/6203/4736/6206/6194/6191/6166/6128/6132/6147/6129/6217/6176/6136/6125/6224/6146/6154/6141/10480/6202/6134/6169/6160/6164/6155/6175/6218/6209/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/8894/1981/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/1974/6122/6133/1968/6230 77 Human_parvovirus R-HSA-927802 Nonsense-Mediated Decay (NMD) 78/1519 115/10654 1.634590722947911e-39 1.9600228759711765e-37 1.20599947118932e-37 6158/9887/6138/6144/6203/4736/6206/6194/6191/6166/6128/6132/6147/6129/6217/6176/6136/6125/6224/6146/6154/6141/26986/6202/2935/6134/6169/6160/6164/6155/6175/6218/6209/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/55802/1981/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/5518/3921/6188/6189/23293/9775/6135/6201/6161/9045/5976/6187/6168/6208/6157/6137/6122/6133/5515/6230 78 Human_parvovirus R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 78/1519 115/10654 1.634590722947911e-39 1.9600228759711765e-37 1.20599947118932e-37 6158/9887/6138/6144/6203/4736/6206/6194/6191/6166/6128/6132/6147/6129/6217/6176/6136/6125/6224/6146/6154/6141/26986/6202/2935/6134/6169/6160/6164/6155/6175/6218/6209/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/55802/1981/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/5518/3921/6188/6189/23293/9775/6135/6201/6161/9045/5976/6187/6168/6208/6157/6137/6122/6133/5515/6230 78 Human_parvovirus R-HSA-2408557 Selenocysteine synthesis 69/1519 93/10654 3.6985859889677836e-39 3.7526422457296206e-37 2.3089957874446653e-37 6158/6138/6144/6203/4736/6206/6194/6191/6166/6128/6132/6147/6129/6217/6176/6136/6125/6224/6146/6154/6141/6202/6134/6169/6160/6164/6155/6175/6218/79048/6209/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133/6230 69 Human_parvovirus R-HSA-72764 Eukaryotic Translation Termination 69/1519 93/10654 3.6985859889677836e-39 3.7526422457296206e-37 2.3089957874446653e-37 6158/6138/6144/6203/4736/6206/6194/6191/6166/6128/6132/6147/6129/6217/6176/6136/6125/6224/6146/6154/6141/6202/2935/6134/6169/6160/6164/6155/6175/6218/6209/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133/6230 69 Human_parvovirus R-HSA-168255 Influenza Life Cycle 87/1519 144/10654 5.111617086792905e-38 4.815873526771316e-36 2.9632005818927298e-36 6158/23165/3303/6138/4928/6144/6203/4736/2926/6206/6194/6191/6166/6128/6132/9631/6147/6129/6217/6176/6136/6125/821/811/6224/6146/6154/6141/6202/57122/5441/6134/6169/5431/6160/23511/6164/6155/6175/6218/5611/6209/6210/4927/6229/6231/11224/6205/6165/6130/2962/6142/6167/6204/9883/6228/23521/3320/6156/6235/6143/6181/6124/6207/6139/6233/7514/7311/6223/25873/1211/3921/6188/6189/6135/6201/6161/3304/9045/6187/6168/6208/6157/6137/6122/6133/6230 87 Human_parvovirus R-HSA-72689 Formation of a pool of free 40S subunits 70/1519 101/10654 1.6121998765827693e-36 1.4176610914751153e-34 8.722849858563616e-35 6158/6138/6144/6203/4736/6206/6194/6191/6166/6128/6132/6147/6129/6217/6176/6136/6125/6224/6146/6154/6141/10480/6202/6134/6169/6160/6164/6155/6175/6218/6209/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/8664/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133/6230 70 Human_parvovirus R-HSA-168273 Influenza Viral RNA Transcription and Replication 81/1519 134/10654 1.7582230970282955e-35 1.449435165612701e-33 8.918355314531683e-34 6158/23165/6138/4928/6144/6203/4736/2926/6206/6194/6191/6166/6128/6132/9631/6147/6129/6217/6176/6136/6125/6224/6146/6154/6141/6202/57122/5441/6134/6169/5431/6160/23511/6164/6155/6175/6218/5611/6209/6210/4927/6229/6231/11224/6205/6165/6130/2962/6142/6167/6204/9883/6228/23521/3320/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133/6230 81 Human_parvovirus R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 71/1519 112/10654 3.7514875949407704e-33 2.91071302219228e-31 1.7909578549221885e-31 6158/6138/6144/6203/4736/6206/6194/6191/6166/6128/6132/6147/6129/6217/6176/6136/6125/6224/6146/6154/6141/6202/6134/6747/6169/6160/6731/6164/6155/6175/6218/60559/6209/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133/6230 71 Human_parvovirus R-HSA-5663205 Infectious disease 146/1519 383/10654 3.219800471562126e-32 2.3593982344391355e-30 1.4517345985815203e-30 6158/23165/3303/5905/6138/8945/1173/4928/6144/3838/6203/5684/8065/4736/2926/6206/6194/6191/162/6166/6128/5606/6132/9631/5604/1499/1938/6147/6129/6217/5707/6176/6136/1174/7520/8106/6125/821/84168/811/6224/6146/6154/6141/9636/6202/57122/5705/5441/10197/160/6134/6169/5431/6160/23511/6164/7316/6155/6175/293/6218/5695/5611/292/567/6209/51271/5714/6714/6210/4927/5605/6229/6231/11224/8148/6205/6165/6130/2962/6142/6167/6204/23327/9883/867/6228/8812/23521/8732/999/5708/3320/2965/5686/6156/27183/6235/905/6143/2068/6181/6124/2071/5902/6207/5478/6139/6233/2885/7514/163/7311/6223/25873/5610/6908/1211/3921/6188/6189/7040/7251/11198/6135/6201/6161/3304/6829/1104/2547/9045/2961/6187/6416/6168/6208/6157/6137/8178/6122/6133/7296/7314/6230 146 Human_parvovirus R-HSA-2408522 Selenoamino acid metabolism 71/1519 118/10654 4.813278378277952e-31 3.341428516288746e-29 2.0559765261231583e-29 6158/6138/6144/6203/4736/6206/6194/6191/6166/6128/6132/6147/6129/6217/6176/6136/6125/6224/6146/6154/6141/6202/6134/6169/6160/6164/6155/6175/6218/79048/6209/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/51540/23521/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133/7296/6230 71 Human_parvovirus R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 92/1519 185/10654 5.793393395679755e-31 3.8207429444507985e-29 2.3508980568784695e-29 84946/6158/6138/6144/6203/23246/55813/4736/6206/6194/6191/6166/6128/6132/6147/25879/6129/6217/9277/6176/6136/10528/27340/27043/6125/6224/6146/6154/6141/6202/51096/90459/6134/6169/6160/6164/6155/6175/6218/6209/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/51077/6156/117246/10171/6235/55720/6143/6181/6124/6207/6139/6233/23160/7311/6223/25873/83732/26168/3921/6188/6189/51010/26354/6135/6201/6161/79707/1453/51202/9045/6187/4691/6168/6208/6157/6137/10885/6122/6133/6230 92 Human_parvovirus R-HSA-8868773 rRNA processing in the nucleus and cytosol 93/1519 195/10654 1.7461210439327168e-29 1.0967303128320255e-27 6.7481670419655385e-28 84946/6158/6138/6144/6203/23246/55813/4736/6206/6194/6191/6166/6128/6132/6147/25879/6129/6217/55226/9277/6176/6136/10528/27340/27043/6125/6224/6146/6154/6141/6202/51096/90459/6134/6169/6160/6164/6155/6175/6218/6209/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/51077/6156/117246/10171/6235/55720/6143/6181/6124/6207/6139/6233/23160/7311/6223/25873/83732/26168/3921/6188/6189/51010/26354/6135/6201/6161/79707/1453/51202/9045/6187/4691/6168/6208/6157/6137/10885/6122/6133/6230 93 Human_parvovirus R-HSA-913531 Interferon Signaling 93/1519 199/10654 1.2497492992967602e-28 7.492815117147393e-27 4.6103191854440305e-27 3135/23165/3665/3120/3460/4928/3838/51447/10379/5335/115362/960/9631/7412/3117/3107/3119/4502/2633/4600/3123/163351/9636/2209/317649/3383/57122/8638/25820/1982/7706/2634/3662/3115/9470/23511/4684/7316/3122/3394/2317/3663/115361/3664/567/3434/6672/3113/6772/4927/3659/3106/23586/8672/25939/9883/4939/388646/10437/2635/1981/1973/3454/3661/7324/9246/1977/5371/51191/4599/6233/684/3716/7311/81603/3133/7318/5610/3134/9775/3127/4940/7334/4938/5781/4261/3105/3660/5495/5724/1974/7314/5595 93 Human_parvovirus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 84/1519 171/10654 7.173725604679956e-28 4.1139756837273314e-26 2.5313237717200216e-26 6158/6138/6144/6203/5684/4736/6206/6194/6191/6166/6128/6132/6147/6129/6217/5707/6176/6136/6125/6224/6146/6154/6141/26986/6202/5705/10197/2935/6134/6169/6160/6091/6164/7316/6155/6175/6218/5695/6209/5714/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/1605/5708/5686/1981/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/9775/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133/7314/6230 84 Human_parvovirus R-HSA-376176 Signaling by ROBO receptors 97/1519 218/10654 1.0022301402186451e-27 5.508089812284971e-26 3.3891203425814716e-26 6158/6138/6144/25/55740/6203/5684/4736/6206/6194/6191/6166/6128/6132/57522/2817/6147/6129/6217/5707/5567/6176/6136/6125/27/6224/6146/6154/6141/26986/6202/5705/10197/2935/6134/6169/6160/6091/6164/7316/6155/6175/6218/5695/5216/6209/5714/6714/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/4650/6228/23521/1605/5708/5686/1981/7408/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/9775/5217/6135/6201/6161/23332/9045/6187/6168/6208/6157/6137/6122/80728/6133/7314/6230 97 Human_parvovirus R-HSA-72312 rRNA processing 93/1519 205/10654 2.1003187526329034e-27 1.1081281738891198e-25 6.818297929599869e-26 84946/6158/6138/6144/6203/23246/55813/4736/6206/6194/6191/6166/6128/6132/6147/25879/6129/6217/55226/9277/6176/6136/10528/27340/27043/6125/6224/6146/6154/6141/6202/51096/90459/6134/6169/6160/6164/6155/6175/6218/6209/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/51077/6156/117246/10171/6235/55720/6143/6181/6124/6207/6139/6233/23160/7311/6223/25873/83732/26168/3921/6188/6189/51010/26354/6135/6201/6161/79707/1453/51202/9045/6187/4691/6168/6208/6157/6137/10885/6122/6133/6230 93 Human_parvovirus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 50/1519 78/10654 5.119113056442991e-24 2.5969654313262714e-22 1.5979093791569016e-22 1147/3665/351/7186/4790/80143/7321/8737/9140/29110/57506/79132/4214/9636/54476/841/7706/8517/84166/7323/9474/7316/5970/4792/4793/23586/7322/1387/843/2033/64135/83737/3661/9246/7189/51191/6233/10010/7311/55593/84282/7318/79671/7187/5094/8772/9641/3551/4791/7314 50 Human_parvovirus R-HSA-877300 Interferon gamma signaling 52/1519 92/10654 2.63740238221641e-21 1.2884199044975723e-19 7.927630552393188e-20 3135/3665/3120/3460/10379/115362/960/7412/3117/3107/3119/4502/2633/3123/163351/2209/3383/8638/7706/2634/3662/3115/4684/3122/3394/3663/115361/3664/567/6672/3113/6772/3659/3106/4939/388646/10437/2635/3661/5371/3716/81603/3133/3134/3127/4940/4938/5781/4261/3105/3660/5724 52 Human_parvovirus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 28/1519 34/10654 9.319698626719437e-19 4.390243745943906e-17 2.7013111433085293e-17 7321/9140/29110/57506/9636/54476/7706/84166/7323/9474/7316/23586/7322/64135/83737/3661/9246/51191/6233/7311/55593/84282/7318/79671/7187/5094/9641/7314 28 Human_parvovirus R-HSA-72766 Translation 100/1519 291/10654 1.6824838243057476e-18 7.436050643684524e-17 4.575392080348565e-17 6158/6138/6144/6203/4736/51253/6206/6194/6191/6166/6128/6132/1917/1938/6147/6129/1915/6217/1936/6176/6136/64432/6125/1937/6224/6146/6154/6141/10480/26986/6202/2935/6134/6747/6169/6160/6731/6164/6155/6175/6218/64963/60559/6209/6210/6229/6231/11224/6205/6165/6130/8890/64968/6142/11222/6167/6204/6228/23521/8894/5018/1981/6156/6235/6143/1973/6181/6124/6207/1977/6139/8893/90480/6233/1975/55168/7311/6223/25873/8664/3921/6188/6189/26589/10102/6135/6201/1978/6161/9045/6187/6168/6208/6157/6137/1974/6122/6133/1968/6230 100 Human_parvovirus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 45/1519 80/10654 1.6912927923467455e-18 7.436050643684524e-17 4.575392080348565e-17 23165/4928/3838/5335/9631/4600/9636/317649/57122/8638/25820/1982/7706/9470/23511/7316/2317/3434/6772/4927/23586/8672/9883/4939/1981/1973/3661/7324/9246/1977/51191/4599/6233/3716/7311/7318/5610/9775/4940/7334/4938/5495/1974/7314/5595 45 Human_parvovirus R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 37/1519 59/10654 1.2360523226307823e-17 5.259203269516135e-16 3.2359807835257496e-16 6203/6206/6194/6191/6217/6224/10480/26986/6202/6218/6209/6210/6229/6231/6205/6204/6228/8894/1981/6235/1973/6207/1977/6233/1975/6223/8664/3921/6188/6189/6201/1978/6187/6208/1974/1968/6230 37 Human_parvovirus R-HSA-1169408 ISG15 antiviral mechanism 41/1519 72/10654 3.1130878150849304e-17 1.2831758837803197e-15 7.895364162600269e-16 23165/4928/3838/5335/9631/4600/9636/317649/57122/25820/1982/7706/9470/23511/7316/2317/3434/6772/4927/23586/8672/9883/1981/1973/3661/7324/9246/1977/51191/4599/6233/3716/7311/7318/5610/9775/7334/5495/1974/7314/5595 41 Human_parvovirus R-HSA-72649 Translation initiation complex formation 36/1519 58/10654 5.55414542415665e-17 2.2199750952917033e-15 1.365947726323693e-15 6203/6206/6194/6191/6217/6224/10480/26986/6202/6218/6209/6210/6229/6231/6205/6204/6228/8894/1981/6235/1973/6207/1977/6233/1975/6223/8664/3921/6188/6189/6201/6187/6208/1974/1968/6230 36 Human_parvovirus R-HSA-166166 MyD88-independent TLR4 cascade 48/1519 99/10654 3.662413640991082e-16 1.3802067407049247e-14 8.492393735952254e-15 1147/3665/8945/5601/351/4790/5606/5604/387522/7321/8737/29110/5594/841/8517/7323/7316/79155/7335/5970/4792/4793/7322/5519/1432/329/100302736/3656/3661/7189/6233/10010/6196/7311/5518/7187/8772/9641/7334/3551/6416/5781/4791/7314/5595/5515/148022/5516 48 Human_parvovirus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 48/1519 99/10654 3.662413640991082e-16 1.3802067407049247e-14 8.492393735952254e-15 1147/3665/8945/5601/351/4790/5606/5604/387522/7321/8737/29110/5594/841/8517/7323/7316/79155/7335/5970/4792/4793/7322/5519/1432/329/100302736/3656/3661/7189/6233/10010/6196/7311/5518/7187/8772/9641/7334/3551/6416/5781/4791/7314/5595/5515/148022/5516 48 Human_parvovirus R-HSA-72702 Ribosomal scanning and start codon recognition 35/1519 58/10654 5.381274504139695e-16 1.9716391863778495e-14 1.2131469715472823e-14 6203/6206/6194/6191/6217/6224/10480/6202/6218/6209/6210/6229/6231/6205/6204/6228/8894/1981/6235/1973/6207/1977/6233/1975/6223/8664/3921/6188/6189/6201/6187/6208/1974/1968/6230 35 Human_parvovirus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 46/1519 94/10654 9.667846416849573e-16 3.4464566010336713e-14 2.1206001671098212e-14 1147/3665/8945/5601/351/4790/5606/5604/387522/7321/8737/29110/5594/841/8517/7323/7316/79155/7335/5970/4792/4793/7322/5519/1432/329/3656/3661/7189/6233/10010/6196/7311/5518/7187/8772/9641/7334/3551/6416/4791/7314/5595/5515/148022/5516 46 Human_parvovirus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 26/1519 39/10654 1.034649372960818e-13 3.591322428777155e-12 2.2097359184287834e-12 6118/5982/9636/7706/7316/11201/5425/5111/9100/10459/7415/6119/51455/5429/5985/5984/9246/6233/51426/7311/7318/5983/6117/5981/55666/7314 26 Human_parvovirus R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 30/1519 51/10654 1.7555385840931932e-13 5.937321519022876e-12 3.653226041392314e-12 6203/6206/6194/6191/6217/6224/10480/6202/6218/6209/6210/6229/6231/6205/6204/6228/8894/6235/6207/6233/6223/8664/3921/6188/6189/6201/6187/6208/1968/6230 30 Human_parvovirus R-HSA-5656169 Termination of translesion DNA synthesis 23/1519 32/10654 2.305834424701308e-13 7.603489015452564e-12 4.678416688012391e-12 6118/5982/9636/7706/7316/11201/5425/5111/9100/6119/51455/5429/5985/5984/9246/6233/51426/7311/7318/5983/6117/5981/7314 23 Human_parvovirus R-HSA-5655862 Translesion synthesis by POLK 16/1519 17/10654 4.0148521559180014e-13 1.2608547603942486e-11 7.758022586999448e-12 6118/5982/7316/5111/10459/6119/51455/5985/5984/6233/51426/7311/5983/6117/5981/7314 16 Human_parvovirus R-HSA-5656121 Translesion synthesis by POLI 16/1519 17/10654 4.0148521559180014e-13 1.2608547603942486e-11 7.758022586999448e-12 6118/5982/7316/11201/5111/10459/6119/51455/5985/5984/6233/7311/5983/6117/5981/7314 16 Human_parvovirus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 51/1519 129/10654 1.104927127548563e-12 3.389299723805941e-11 2.0854316164992467e-11 1147/3665/8945/5601/351/4790/5606/5604/387522/7321/8737/5336/29110/5594/1785/4214/841/8517/7323/7316/79155/7335/5970/4792/4793/7322/5519/1432/329/100302736/3656/3661/7189/6233/10010/6196/7311/5518/7187/8772/9641/7334/3551/6416/5781/4791/7314/5595/5515/148022/5516 51 Human_parvovirus R-HSA-73893 DNA Damage Bypass 28/1519 48/10654 1.5153706019860986e-12 4.542667781862873e-11 2.7950974500748377e-11 6118/5982/9636/7706/7316/11201/5425/5111/9100/10459/7415/6119/51455/1642/5429/5985/5984/9246/6233/51426/7311/7318/5983/6117/5981/55666/7314/8451 28 Human_parvovirus R-HSA-168898 Toll-like Receptor Cascades 57/1519 155/10654 1.8576442799239245e-12 5.444961789377014e-11 3.350277753968061e-11 1147/3665/8945/10695/5601/351/4790/5606/5604/387522/7321/8737/5336/29110/5594/1785/4214/6280/841/8517/7323/7316/79155/7335/5970/4792/4793/6279/5641/7322/5519/1432/329/100302736/3656/3661/7189/6233/10010/6196/7311/5518/7187/8772/9641/64145/7334/3551/6416/5781/4791/1508/7314/5595/5515/148022/5516 57 Human_parvovirus R-HSA-71291 Metabolism of amino acids and derivatives 104/1519 372/10654 1.9780816219357314e-012 5.6719340420287606e-11 3.489933479433522e-11 6158/440/4967/6138/6144/6203/5684/4736/1728/6206/6194/256987/6191/6166/6128/6132/6147/6129/5160/6217/5707/6176/383/6136/6125/54498/1737/57407/6224/6146/6154/6141/6202/5705/4947/10197/6134/6169/6160/6164/6155/6175/6218/5695/79048/10165/5723/6209/5714/8140/6210/6229/6231/11224/6205/23446/6165/84245/6130/6142/6167/6204/6228/2752/51540/23521/4946/5708/5686/445/6156/6235/6143/6181/6124/26227/64087/6207/3034/6139/6520/6233/587/7311/6223/25873/4507/3921/6188/6189/6135/6201/1734/6161/9045/6187/6168/6208/6157/6137/6122/6133/7296/6230 104 Human_parvovirus R-HSA-110312 Translesion synthesis by REV1 15/1519 16/10654 2.6743350536564898e-12 7.505208373984914e-11 4.6179447399085196e-11 6118/5982/7316/5111/10459/6119/51455/5985/5984/6233/7311/5983/6117/5981/7314 15 Human_parvovirus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 17/1519 20/10654 2.8561868189210896e-12 7.848563362826911e-11 4.8292106083073694e-11 1147/387522/7321/8737/8517/7323/7316/7335/7322/329/7189/6233/7311/7334/3551/7314/148022 17 Human_parvovirus R-HSA-110320 Translesion Synthesis by POLH 16/1519 19/10654 1.7206677560171065e-11 4.63175667385013e-10 2.849913726937034e-10 6118/5982/7316/5111/7415/6119/5429/5985/5984/6233/7311/5983/6117/5981/55666/7314 16 Human_parvovirus R-HSA-6806003 Regulation of TP53 Expression and Degradation 23/1519 37/10654 2.4373985224487114e-11 6.429857302219701e-10 3.95628265433254e-10 6446/117584/639/7316/80196/983/64223/5519/1616/900/7157/6233/5527/2475/7311/5518/7874/51230/7314/253260/4193/5515/5516 23 Human_parvovirus R-HSA-170834 Signaling by TGF-beta Receptor Complex 34/1519 73/10654 3.157439178873364e-11 8.166004464576407e-10 5.024531696411484e-10 892/7321/6497/10273/51592/7323/8239/7316/9611/5501/9612/56937/4609/4089/60436/23327/867/8812/7046/4088/905/9958/5499/6233/7514/7048/7311/56288/25937/9110/7040/57530/5500/7314 34 Human_parvovirus R-HSA-5689896 Ovarian tumor domain proteases 23/1519 38/10654 5.344410017204605e-11 1.3556301562870913e-9 8.341174338592614e-10 7321/8737/57506/7706/8517/7316/79155/983/2099/7415/23586/324/64135/7157/7189/6233/7311/55593/84282/78990/7187/23252/7314 23 Human_parvovirus R-HSA-5663202 Diseases of signal transduction 101/1519 377/10654 6.419202757211956e-11 1.5975336673136925e-9 9.829603427627445e-10 4000/1147/27044/5684/5335/79718/1487/5604/1499/5525/892/55750/5707/1452/5594/84335/613/4041/1027/5908/930/7414/10533/5705/5441/23164/10197/5431/6776/2100/7316/9611/5695/3714/8546/6774/8658/9612/102/50852/57085/5714/6772/6714/2099/5605/4609/10818/7415/64223/4089/2962/5519/8850/867/1387/7046/4088/6907/5708/3320/5686/324/2033/391/55294/6400/8312/5529/3066/5894/6233/5527/2885/1488/2475/56829/7048/7311/8826/5906/2931/5518/4140/7040/3845/6777/80351/5781/4851/7750/5245/7529/7314/1523/57670/253260/5595/4193/5515/5516 101 Human_parvovirus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12/1519 12/10654 6.796958194172826e-11 1.6602199737248069e-9 1.0215311438025828e-9 1147/8737/57506/841/7706/8517/23586/843/64135/84282/8772/3551 12 Human_parvovirus R-HSA-937041 IKK complex recruitment mediated by RIP1 18/1519 25/10654 9.576247891682916e-11 2.2965583580235937e-9 1.4130693061220151e-9 1147/387522/7321/8737/8517/7323/7316/7335/7322/329/100302736/7189/6233/7311/7334/3551/7314/148022 18 Human_parvovirus R-HSA-6804757 Regulation of TP53 Degradation 22/1519 36/10654 1.0795666691170919e-10 2.542765065295436e-9 1.5645599659572893e-9 6446/117584/7316/80196/983/64223/5519/1616/900/7157/6233/5527/2475/7311/5518/7874/51230/7314/253260/4193/5515/5516 22 Human_parvovirus R-HSA-918233 TRAF3-dependent IRF activation pathway 13/1519 14/10654 1.170423423094961e-10 2.7084008685302694e-9 1.6664754555978118e-9 3665/80143/29110/57506/7706/23586/1387/2033/64135/3661/84282/7187/9641 13 Human_parvovirus R-HSA-1295596 Spry regulation of FGF signaling 14/1519 16/10654 1.2316558045564358e-10 2.800955183120584e-9 1.7234240023829624e-9 5594/7316/6714/8569/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 14 Human_parvovirus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 30/1519 63/10654 2.307332843037092e-10 5.158257660959194e-9 3.1738690847129314e-9 1147/3665/170506/55718/4790/1499/8737/29110/81844/7520/5441/51082/8517/5591/7316/5970/4792/4793/1387/2033/22954/1660/3661/6233/7311/3551/2547/4791/7314/148022 30 Human_parvovirus R-HSA-933542 TRAF6 mediated NF-kB activation 17/1519 24/10654 4.896948891572966e-10 1.076512597997457e-8 6.623767711232907e-9 1147/351/7186/4790/57506/4214/7706/8517/5970/4792/4793/23586/64135/7189/84282/3551/4791 17 Human_parvovirus R-HSA-909733 Interferon alpha/beta signaling 31/1519 69/10654 7.203573543114199e-10 1.5576251644864964e-8 9.584046940019064e-9 3135/3665/51447/10379/3107/4600/9636/8638/2634/3662/3394/3663/3664/3434/6772/3659/3106/25939/4939/3454/3661/4599/684/3716/3133/3134/4940/4938/5781/3105/3660 31 Human_parvovirus R-HSA-5633007 Regulation of TP53 Activity 52/1519 160/10654 2.9776669165887684e-9 6.334746230613847e-8 3.89776093835304e-8 23368/23774/6118/9156/5883/6446/5982/117584/639/7316/28996/80196/84289/54971/983/1108/8148/64223/5519/6119/5928/1432/10848/57459/1616/6794/5985/54815/2033/900/3066/7157/1107/5984/5371/6233/5527/2475/672/7311/5518/6908/5983/6117/11198/7874/51230/7314/253260/4193/5515/5516 52 Human_parvovirus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 17/1519 26/10654 3.3235057316698502e-9 6.958260412813544e-8 4.281408386161161e-8 10273/7316/5501/56937/23327/7046/4088/9958/5499/6233/7514/7048/7311/9110/7040/5500/7314 17 Human_parvovirus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 19/1519 32/10654 4.120968612003063e-9 8.493058748800063e-8 5.225767762918359e-8 10273/7316/5501/56937/4089/23327/867/7046/4088/9958/5499/6233/7514/7048/7311/9110/7040/5500/7314 19 Human_parvovirus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 37/1519 97/10654 4.5405458185254434e-9 9.079874699428433e-8 5.586834837603704e-8 1147/3665/8945/5601/351/4790/5606/5604/387522/5594/4214/8517/7316/79155/7335/5970/4792/4793/5519/1432/100302736/3656/7189/6233/6196/7311/5518/64145/7334/3551/6416/4791/7314/5595/5515/148022/5516 37 Human_parvovirus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 36/1519 93/10654 4.612218384091774e-9 9.079874699428433e-8 5.586834837603704e-8 1147/3665/8945/5601/351/4790/5606/5604/387522/5594/4214/8517/7316/79155/7335/5970/4792/4793/5519/1432/100302736/3656/7189/6233/6196/7311/5518/7334/3551/6416/4791/7314/5595/5515/148022/5516 36 Human_parvovirus R-HSA-975155 MyD88 dependent cascade initiated on endosome 36/1519 93/10654 4.612218384091774e-9 9.079874699428433e-8 5.586834837603704e-8 1147/3665/8945/5601/351/4790/5606/5604/387522/5594/4214/8517/7316/79155/7335/5970/4792/4793/5519/1432/100302736/3656/7189/6233/6196/7311/5518/7334/3551/6416/4791/7314/5595/5515/148022/5516 36 Human_parvovirus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 11/1519 12/10654 5.008835346167338e-9 9.715667384698117e-8 5.978037232035631e-8 3665/29110/7316/3661/6233/10010/7311/7187/9641/7314/148022 11 Human_parvovirus R-HSA-3700989 Transcriptional Regulation by TP53 93/1519 365/10654 6.152531444826205e-9 1.1761143443080819e-7 7.236615932816179e-8 23368/23774/6118/27161/4436/8621/9156/5883/7531/6446/10971/1027/5982/2810/117584/5441/7534/5431/7001/639/64065/7316/28996/80196/84289/54971/983/5111/1108/8148/8797/64223/2962/5519/6119/5928/1432/10848/1387/8812/57459/23019/1616/843/6794/2965/5985/54815/2033/10128/6009/900/905/2068/3066/2071/7157/1107/55215/5984/5371/1337/6233/5527/2475/672/604/7311/5518/6908/5325/581/5983/6117/11198/9167/3276/6829/7874/51230/5052/637/10397/8795/57521/8178/7529/7296/7314/253260/4193/5515/5516 93 Human_parvovirus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 35/1519 92/10654 1.2824229843765274e-8 2.4164513091323425e-7 1.4868392796305304e-7 1147/8945/5601/351/4790/5606/5604/387522/5594/4214/8517/7316/79155/7335/5970/4792/4793/5519/1432/100302736/3656/7189/6233/6196/7311/5518/7334/3551/6416/4791/7314/5595/5515/148022/5516 35 Human_parvovirus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 33/1519 85/10654 1.8522732558020942e-8 3.346778663565702e-7 2.0592684646336192e-7 1147/8945/5601/351/4790/5606/5604/387522/5594/4214/8517/7316/79155/7335/5970/4792/4793/5519/1432/3656/7189/6233/6196/7311/5518/7334/3551/6416/4791/7314/5595/5515/5516 33 Human_parvovirus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 33/1519 85/10654 1.8522732558020942e-8 3.346778663565702e-7 2.0592684646336192e-7 1147/8945/5601/351/4790/5606/5604/387522/5594/4214/8517/7316/79155/7335/5970/4792/4793/5519/1432/3656/7189/6233/6196/7311/5518/7334/3551/6416/4791/7314/5595/5515/5516 33 Human_parvovirus R-HSA-975871 MyD88 cascade initiated on plasma membrane 33/1519 85/10654 1.8522732558020942e-8 3.346778663565702e-7 2.0592684646336192e-7 1147/8945/5601/351/4790/5606/5604/387522/5594/4214/8517/7316/79155/7335/5970/4792/4793/5519/1432/3656/7189/6233/6196/7311/5518/7334/3551/6416/4791/7314/5595/5515/5516 33 Human_parvovirus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 15/1519 23/10654 3.0362263832328825e-008 5.408752908554194e-7 3.327998477710614e-7 7321/6497/51592/7323/8239/7316/9611/9612/4089/60436/23327/4088/6233/7311/7314 15 Human_parvovirus R-HSA-983169 Class I MHC mediated antigen processing & presentation 92/1519 371/10654 3.075484974538018e-8 5.408752908554194e-7 3.327998477710614e-7 1147/3135/8945/5684/79754/8065/246184/387522/3107/7321/5707/84231/10273/10484/154881/821/811/10533/2209/5705/10197/53339/8517/26263/51619/9690/9554/7326/7323/57630/7316/5695/7317/80196/22872/7335/567/7337/5714/3106/26118/25831/7322/10489/23327/9341/63893/6502/118424/10616/3309/5708/5686/55294/10422/22954/83737/51529/7324/10075/64682/9246/8924/51191/6233/9520/51434/90025/7327/3685/25793/51343/7311/26091/6047/3133/7318/3134/80204/26232/57520/27338/7334/55182/3551/7332/3105/10427/9820/7314/642/899 92 Human_parvovirus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 13/1519 18/10654 4.0812939033125255e-8 7.083192971670028e-7 4.35827922362044e-7 3665/29110/7316/100302736/3661/6233/10010/7311/7187/9641/5781/7314/148022 13 Human_parvovirus R-HSA-450294 MAP kinase activation 27/1519 64/10654 4.6665506026558245e-8 7.993740577796147e-7 4.918537955772579e-7 1147/8945/5601/4790/5606/5604/387522/5594/8517/7316/79155/7335/5519/1432/3656/7189/6233/6196/7311/5518/7334/3551/6416/7314/5595/5515/5516 27 Human_parvovirus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 18/1519 33/10654 6.586011932946633e-8 1.1137115050713601e-6 6.852652092175242e-7 1147/351/4790/387522/8517/7316/7335/5970/4792/4793/3656/7189/6233/7311/7334/3551/4791/7314 18 Human_parvovirus R-HSA-3371556 Cellular response to heat stress 33/1519 89/10654 6.887801934578486e-8 1.1500013609758256e-6 7.075943093351117e-7 23165/3303/6118/4928/9631/7531/1915/5594/3308/84335/10049/57122/23511/3305/9532/4927/7415/64223/6119/9883/1387/3309/3320/2033/22824/2475/3306/6117/3304/3312/57521/10728/5595 33 Human_parvovirus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 12/1519 16/10654 7.068943886503627e-8 1.1654921232872854e-6 7.171257548018811e-7 1147/8945/4790/5604/8517/7316/79155/6233/7311/3551/6416/7314 12 Human_parvovirus R-HSA-9006936 Signaling by TGF-beta family members 36/1519 102/10654 7.705873230704016e-8 1.2548205915183453e-6 7.720894426085506e-7 10272/892/7321/6497/10273/51592/7323/8239/7316/9611/5501/9612/56937/4609/4089/60436/23327/867/8812/7046/4088/905/9958/5499/657/6233/7514/7048/7311/56288/25937/9110/7040/57530/5500/7314 36 Human_parvovirus R-HSA-5675221 Negative regulation of MAPK pathway 20/1519 40/10654 8.415716306306631e-8 1.3536987570754203e-6 8.329290464906821e-7 5604/5525/5594/7316/5605/5519/5529/5894/6233/5527/7311/5518/5536/4140/3845/7529/7314/5595/5515/5516 20 Human_parvovirus R-HSA-5696400 Dual Incision in GG-NER 20/1519 41/10654 1.4238651581505486e-7 2.2627447513259923e-006 1.392263838851076e-6 6118/5982/7316/5425/5111/6119/1642/2965/5985/2068/2071/5984/6233/51426/7311/5983/6117/5981/7314/8451 20 Human_parvovirus R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 15/1519 25/10654 1.5253533054014496e-7 2.3951678688387048e-6 1.4737436070983933e-6 6118/5982/7316/5425/5111/6119/5985/5984/6233/51426/7311/5983/6117/5981/7314 15 Human_parvovirus R-HSA-69242 S Phase 48/1519 161/10654 2.4171826665914424e-7 3.750898749687191e-6 2.307923016646443e-6 6118/5684/246184/7321/5707/1027/5982/5925/23244/4173/5705/10197/4149/23047/91768/7316/5422/5753/5695/5425/5714/5111/4171/4609/6119/5928/6502/5708/5985/5686/595/51529/5984/7324/64682/6233/51434/51343/7311/114799/113130/5983/6117/5001/5981/7465/4176/7314 48 Human_parvovirus R-HSA-202424 Downstream TCR signaling 34/1519 98/10654 2.8235878169551714e-7 4.330595733213803e-6 2.664609800333461e-6 1147/3120/8945/5684/4790/387522/3117/7321/5707/3119/3123/5705/10197/8517/3115/7316/3122/5695/7335/5970/4792/50852/5714/3113/7322/5708/5686/7189/6233/7311/3127/7334/3551/7314 34 Human_parvovirus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 26/1519 65/10654 2.966786916601522e-7 4.497921773560239e-6 2.767565290622836e-6 6118/27339/5982/5441/5431/7316/5425/5111/6119/1161/1642/2965/5985/2033/2068/2071/5984/6233/51426/7311/5983/6117/5981/7874/7314/8451 26 Human_parvovirus R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 11/1519 15/10654 3.756649979607486e-7 5.215811919055025e-6 3.2092821432436258e-6 1499/5525/1452/5519/324/8312/5529/5527/5518/5515/5516 11 Human_parvovirus R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 11/1519 15/10654 3.756649979607486e-7 5.215811919055025e-6 3.2092821432436258e-6 1499/5525/1452/5519/324/8312/5529/5527/5518/5515/5516 11 Human_parvovirus R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 11/1519 15/10654 3.756649979607486e-7 5.215811919055025e-6 3.2092821432436258e-6 1499/5525/1452/5519/324/8312/5529/5527/5518/5515/5516 11 Human_parvovirus R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 11/1519 15/10654 3.756649979607486e-7 5.215811919055025e-6 3.2092821432436258e-6 1499/5525/1452/5519/324/8312/5529/5527/5518/5515/5516 11 Human_parvovirus R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 11/1519 15/10654 3.756649979607486e-7 5.215811919055025e-6 3.2092821432436258e-6 1499/5525/1452/5519/324/8312/5529/5527/5518/5515/5516 11 Human_parvovirus R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 11/1519 15/10654 3.756649979607486e-7 5.215811919055025e-6 3.2092821432436258e-6 1499/5525/1452/5519/324/8312/5529/5527/5518/5515/5516 11 Human_parvovirus R-HSA-937039 IRAK1 recruits IKK complex 11/1519 15/10654 3.756649979607486e-7 5.215811919055025e-6 3.2092821432436258e-6 1147/387522/8517/7316/7335/7189/6233/7311/7334/3551/7314 11 Human_parvovirus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 11/1519 15/10654 3.756649979607486e-7 5.215811919055025e-6 3.2092821432436258e-6 1147/387522/8517/7316/7335/7189/6233/7311/7334/3551/7314 11 Human_parvovirus R-HSA-2262752 Cellular responses to stress 108/1519 479/10654 3.982870248963851e-7 5.472297769149291e-6 3.3670975459990455e-6 23165/3303/6118/84617/4928/55846/5684/5601/4790/5606/9631/9448/246184/112399/7531/7290/1915/7321/5707/2146/475/6045/10382/5594/3308/84335/23677/1027/80012/10049/10294/5925/830/1051/50488/10381/57122/5705/10197/7001/23511/7323/7316/2114/5695/3305/6774/5970/1639/9532/832/5714/2289/4927/7415/1871/64223/7322/6119/9883/5928/1432/1387/112398/3309/347733/5708/3320/5686/2033/23512/1021/6009/51143/3301/7157/51529/6648/7324/10963/64682/22824/8131/6233/51434/2475/3306/51343/6196/7311/2034/10383/6117/648/3304/3312/5052/2113/6416/96459/57521/7280/10728/7296/7314/51164/5595/4193 108 Human_parvovirus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 33/1519 95/10654 4.076709829016917e-7 5.486918637217667e-6 3.3760937466939243e-6 1147/8945/5601/351/4790/5606/5604/387522/5594/4214/8517/7316/79155/7335/5970/4792/4793/5519/1432/3656/7189/6233/6196/7311/5518/7334/3551/6416/4791/7314/5595/5515/5516 33 Human_parvovirus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 33/1519 95/10654 4.076709829016917e-7 5.486918637217667e-6 3.3760937466939243e-6 1147/8945/5601/351/4790/5606/5604/387522/5594/4214/8517/7316/79155/7335/5970/4792/4793/5519/1432/3656/7189/6233/6196/7311/5518/7334/3551/6416/4791/7314/5595/5515/5516 33 Human_parvovirus R-HSA-6782135 Dual incision in TC-NER 26/1519 66/10654 4.2376032066873926e-7 5.645857201637041e-6 3.4738884341903034e-6 6118/27339/5982/5441/5431/7316/5425/5111/6119/1161/1642/2965/5985/2033/2068/2071/5984/6233/51426/7311/5983/6117/5981/7874/7314/8451 26 Human_parvovirus R-HSA-8878159 Transcriptional regulation by RUNX3 33/1519 96/10654 5.373434143680534e-7 7.064678820368646e-6 4.346887490925522e-6 51176/5684/1499/5707/463/5705/10197/7316/865/5695/5714/6714/4609/4089/8850/1387/7005/4088/5708/5686/2033/7003/595/7157/861/6233/7311/25937/7040/3845/4851/7314/4193 33 Human_parvovirus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 16/1519 30/10654 5.409647921586302e-7 7.064678820368646e-6 4.346887490925522e-6 6118/5982/7316/5425/5111/6119/1642/5985/5984/6233/7311/5983/6117/5981/7314/8451 16 Human_parvovirus R-HSA-2132295 MHC class II antigen presentation 39/1519 123/10654 5.707392559744277e-7 7.380441947355591e-6 4.541176123387863e-6 3831/3120/114876/1173/84617/162/6712/3117/3119/10484/10382/1174/1785/821/830/3123/10381/160/3115/3122/1509/22872/1639/832/3113/5641/10437/347733/51143/163/3799/10383/1211/3127/7879/7280/10427/1508/51164 39 Human_parvovirus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 20/1519 44/10654 6.065546365423941e-7 7.7423194630612e-6 4.7638388779539416e-6 892/7321/6497/51592/7323/8239/7316/9611/9612/4609/4089/60436/23327/8812/4088/905/6233/7311/25937/7314 20 Human_parvovirus R-HSA-194315 Signaling by Rho GTPases 103/1519 455/10654 6.104633996651743e-7 7.7423194630612e-6 4.7638388779539416e-6 85415/3831/5905/84617/4928/25/9743/57522/1495/1499/5525/392/7531/5747/10093/7204/29/4627/10971/80152/10458/10382/5594/613/1027/3619/79172/11214/2810/147179/55920/116985/54509/10381/57122/6280/30851/7534/6453/5048/5501/9824/5216/10552/100527963/10152/6279/23263/6714/393/50649/5519/9826/10092/8936/4650/1432/4637/10163/999/23365/1123/347733/23081/3895/11243/391/5529/23221/51143/4628/89941/5527/2885/7410/9055/1857/23191/7514/8826/10499/5518/3799/10383/103910/29984/5347/1729/5217/10095/23332/10726/201176/2665/7280/5500/7529/80728/5595/4983/5515/5516/10672 103 Human_parvovirus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 13/1519 21/10654 6.364296803837399e-7 7.96438109161262e-6 4.900473102935502e-6 1147/4790/8737/29110/8517/5970/4792/4793/1660/3661/3551/4791/148022 13 Human_parvovirus R-HSA-209560 NF-kB is activated and signals survival 10/1519 13/10654 6.400488216155707e-7 7.96438109161262e-6 4.900473102935502e-6 4790/8878/7316/5970/4792/7189/6233/7311/3551/7314 10 Human_parvovirus R-HSA-202403 TCR signaling 38/1519 119/10654 6.507435811053686e-7 8.021783023158703e-6 4.93579243514254e-6 1147/3120/8945/55740/5684/5335/4790/387522/3117/7321/5707/3119/3123/5705/10197/8517/3115/7316/3122/5695/7335/5970/4792/50852/5714/3113/7322/5795/5708/5686/7408/7189/6233/7311/3127/7334/3551/7314 38 Human_parvovirus R-HSA-448424 Interleukin-17 signaling 27/1519 72/10654 8.15868906335487e-7 9.964176735708401e-6 6.130944705503514e-6 1147/8945/5601/4790/5606/5604/387522/5594/8517/7316/79155/7335/5519/1432/3656/7189/6233/6196/7311/5518/7334/3551/6416/7314/5595/5515/5516 27 Human_parvovirus R-HSA-9006925 Intracellular signaling by second messengers 75/1519 305/10654 8.358293954256275e-7 1.0114302500609199e-5 6.2233168891661895e-6 1147/27161/3643/3838/5684/5335/5525/1822/5575/23186/5707/5567/23239/2146/9112/10273/6045/5594/84335/1027/80012/930/112/3708/5705/10197/2100/7316/5695/8658/50852/5714/10645/6714/2099/1108/10818/64223/5519/5928/57459/5708/54815/5686/23512/391/6009/5529/3066/7157/1107/7189/5371/5577/6233/5527/2885/2475/7311/2931/5518/3710/8394/648/80351/7874/5781/57521/23252/7314/253260/5595/4193/5515/5516 75 Human_parvovirus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 33/1519 98/10654 9.187811803386104e-7 1.0917769160960606e-5 6.717688857667794e-6 1147/8945/5601/351/4790/5606/5604/387522/5594/4214/8517/7316/79155/7335/5970/4792/4793/5519/1432/3656/7189/6233/6196/7311/5518/7334/3551/6416/4791/7314/5595/5515/5516 33 Human_parvovirus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 33/1519 98/10654 9.187811803386104e-7 1.0917769160960606e-5 6.717688857667794e-6 1147/8945/5601/351/4790/5606/5604/387522/5594/4214/8517/7316/79155/7335/5970/4792/4793/5519/1432/3656/7189/6233/6196/7311/5518/7334/3551/6416/4791/7314/5595/5515/5516 33 Human_parvovirus R-HSA-8953897 Cellular responses to external stimuli 109/1519 493/10654 9.709209386800868e-7 1.1434327840348521e-5 7.035526726713788e-6 23165/3303/6118/84617/4928/55846/5684/5601/4790/5606/9631/9448/246184/112399/7531/7290/1915/7321/5707/2146/475/4502/6045/10382/5594/3308/84335/23677/1027/80012/10049/10294/5925/830/1051/50488/10381/57122/5705/10197/7001/23511/7323/7316/2114/5695/3305/6774/5970/1639/9532/832/5714/2289/4927/7415/1871/64223/7322/6119/9883/5928/1432/1387/112398/3309/347733/5708/3320/5686/2033/23512/1021/6009/51143/3301/7157/51529/6648/7324/10963/64682/22824/8131/6233/51434/2475/3306/51343/6196/7311/2034/10383/6117/648/3304/3312/5052/2113/6416/96459/57521/7280/10728/7296/7314/51164/5595/4193 109 Human_parvovirus R-HSA-453279 Mitotic G1-G1/S phases 44/1519 149/10654 1.0167859550936373e-6 1.1835432586049175e-5 7.2823259437723275e-6 6118/25/5684/5707/1027/5925/4173/5705/10197/4149/91768/7316/5422/5753/5695/983/5714/5111/6714/4171/4609/1871/5519/6119/5928/4067/6502/5708/5686/1021/595/6233/7311/5518/6117/1719/5001/7465/1859/4176/7314/5515/6241/5516 44 Human_parvovirus R-HSA-72163 mRNA Splicing - Major Pathway 51/1519 183/10654 1.0229259399617938e-6 1.1835432586049175e-5 7.2823259437723275e-6 8449/220988/24148/27339/4904/9879/10523/6428/11325/3184/8106/3178/23450/5441/3183/5431/9092/5093/10594/6625/10713/1655/9343/3185/9416/5546/2962/10236/10189/9295/10949/3181/1660/2521/3191/27316/3187/6634/5094/9775/3192/6427/3312/5725/1479/26121/11100/10992/10262/6628/1994 51 Human_parvovirus R-HSA-193639 p75NTR signals via NF-kB 11/1519 16/10654 1.046611227971321e-6 1.2004175736471066e-5 7.3861533800081345e-6 4790/5584/8878/7316/5970/4792/7189/6233/7311/3551/7314 11 Human_parvovirus R-HSA-195253 Degradation of beta-catenin by the destruction complex 29/1519 82/10654 1.3326725714005529e-6 1.5153406221356288e-5 9.323870712793343e-6 51176/8945/5684/1487/1499/5525/5707/1452/5705/10197/7316/5695/7091/5714/5519/5708/5686/324/8312/5529/7088/6233/5527/1488/7311/5518/7314/5515/5516 29 Human_parvovirus R-HSA-69620 Cell Cycle Checkpoints 72/1519 293/10654 1.4223679690953491e-6 1.6035071378092013e-5 9.866358112213354e-6 6118/5905/4928/5684/9156/246184/5883/5525/7531/7321/5707/10971/80152/51720/1027/3619/5982/79172/2810/4173/55920/57122/5705/10197/7534/29086/5048/7316/5695/5501/983/100527963/5714/4171/5519/9088/6119/5708/5985/5686/11243/5529/51143/7157/51529/5984/7324/64682/8924/6233/5527/51434/672/7514/7311/9025/5518/5347/5983/6117/7334/5001/23332/7465/51230/10726/4176/7529/7314/4193/5515/5516 72 Human_parvovirus R-HSA-68882 Mitotic Anaphase 54/1519 201/10654 1.7284772754925466e-6 1.932086039300567e-5 1.1888099727071843e-5 4000/5905/84617/4928/5684/246184/5525/7321/5707/80152/10382/3619/79172/23244/55920/10381/57122/5705/10197/7443/23047/23141/5048/7316/5695/5501/100527963/5714/5519/347733/5708/5686/11243/5529/51143/51529/7324/64682/23592/6233/5527/51434/7514/7311/5518/10383/5347/113130/23332/10726/7280/7314/5515/5516 54 Human_parvovirus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 28/1519 79/10654 1.922860647990906e-6 2.0602465064291934e-5 1.267666937837204e-5 9318/6118/27339/5982/5441/5431/7316/5425/5111/6119/1161/1642/2965/5985/2033/2068/2071/5984/6233/51426/7311/5983/6117/5981/7874/8178/7314/8451 28 Human_parvovirus R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 10/1519 14/10654 1.9524701539321394e-6 2.0602465064291934e-5 1.267666937837204e-5 5525/1452/5519/324/8312/5529/5527/5518/5515/5516 10 Human_parvovirus R-HSA-4839744 truncated APC mutants destabilize the destruction complex 10/1519 14/10654 1.9524701539321394e-6 2.0602465064291934e-5 1.267666937837204e-5 5525/1452/5519/324/8312/5529/5527/5518/5515/5516 10 Human_parvovirus R-HSA-4839748 AMER1 mutants destabilize the destruction complex 10/1519 14/10654 1.9524701539321394e-6 2.0602465064291934e-5 1.267666937837204e-5 5525/1452/5519/324/8312/5529/5527/5518/5515/5516 10 Human_parvovirus R-HSA-5467337 APC truncation mutants have impaired AXIN binding 10/1519 14/10654 1.9524701539321394e-6 2.0602465064291934e-5 1.267666937837204e-5 5525/1452/5519/324/8312/5529/5527/5518/5515/5516 10 Human_parvovirus R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 10/1519 14/10654 1.9524701539321394e-6 2.0602465064291934e-5 1.267666937837204e-5 5525/1452/5519/324/8312/5529/5527/5518/5515/5516 10 Human_parvovirus R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 10/1519 14/10654 1.9524701539321394e-6 2.0602465064291934e-5 1.267666937837204e-5 5525/1452/5519/324/8312/5529/5527/5518/5515/5516 10 Human_parvovirus R-HSA-2555396 Mitotic Metaphase and Anaphase 54/1519 202/10654 2.038778090475264e-6 2.094351600000612e-5 1.2886517565942876e-5 4000/5905/84617/4928/5684/246184/5525/7321/5707/80152/10382/3619/79172/23244/55920/10381/57122/5705/10197/7443/23047/23141/5048/7316/5695/5501/100527963/5714/5519/347733/5708/5686/11243/5529/51143/51529/7324/64682/23592/6233/5527/51434/7514/7311/5518/10383/5347/113130/23332/10726/7280/7314/5515/5516 54 Human_parvovirus R-HSA-5654732 Negative regulation of FGFR3 signaling 15/1519 29/10654 2.0576051709618333e-6 2.094351600000612e-5 1.2886517565942876e-5 5594/7316/6714/10818/8569/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 15 Human_parvovirus R-HSA-933541 TRAF6 mediated IRF7 activation 15/1519 29/10654 2.0576051709618333e-6 2.094351600000612e-5 1.2886517565942876e-5 3665/7186/80143/29110/57506/7706/23586/1387/2033/64135/3661/7189/10010/84282/9641 15 Human_parvovirus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 50/1519 182/10654 2.05972898546333e-6 2.094351600000612e-5 1.2886517565942876e-5 23165/7150/5905/4928/1487/83746/9631/1788/9112/6045/3619/3090/80012/57122/8517/3183/23511/28996/1655/5970/4792/6996/9612/6672/5111/2099/4927/9883/1387/1616/2033/23512/3066/7157/1107/6256/5371/8924/672/10155/10499/5914/25942/9641/6117/7690/648/4286/4791/4193 50 Human_parvovirus R-HSA-1257604 PIP3 activates AKT signaling 66/1519 264/10654 2.0641827748300195e-6 2.094351600000612e-5 1.2886517565942876e-5 1147/27161/3643/5684/5525/1822/23186/5707/23239/2146/9112/10273/6045/5594/84335/1027/80012/930/5705/10197/2100/7316/5695/8658/50852/5714/6714/2099/1108/10818/64223/5519/5928/57459/5708/54815/5686/23512/391/6009/5529/3066/7157/1107/7189/5371/6233/5527/2885/2475/7311/2931/5518/8394/648/80351/7874/5781/57521/23252/7314/253260/5595/4193/5515/5516 66 Human_parvovirus R-HSA-168638 NOD1/2 Signaling Pathway 17/1519 36/10654 2.205570257450421e-6 2.220723030211531e-5 1.3664079296860385e-5 1147/387522/841/8517/7316/7335/1432/329/3656/83737/7189/6233/7311/7334/3551/6300/7314 17 Human_parvovirus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 62/1519 244/10654 2.3573716157457296e-6 2.3555857281580435e-5 1.4493887685326617e-5 8449/23165/7919/4928/220988/24148/9631/27339/4904/9879/10523/6428/11325/3184/8106/9589/3178/23450/57122/5441/3183/5431/9092/5093/23511/10594/6625/10713/1655/9343/3185/9416/84321/5546/4927/2962/9883/10236/10189/9295/10949/3181/1660/2521/1977/3191/27316/3187/6634/5094/9775/3192/6427/3312/5725/1479/26121/11100/10992/10262/6628/1994 62 Human_parvovirus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 22/1519 55/10654 2.4097340732901404e-6 2.371969584081862e-5 1.4594697333124105e-5 1147/351/4790/387522/841/8517/7316/7335/5970/22861/1432/329/3656/83737/7189/6233/7311/7334/3551/6300/4791/7314 22 Human_parvovirus R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 22/1519 55/10654 2.4097340732901404e-6 2.371969584081862e-5 1.4594697333124105e-5 3303/84617/10382/10294/830/10381/3305/1639/832/2289/347733/3320/51143/3301/10963/3306/10383/3304/3312/7280/10728/51164 22 Human_parvovirus R-HSA-2990846 SUMOylation 51/1519 188/10654 2.4492429293087833e-6 2.3930010546357668e-5 1.4724103691984967e-5 10054/23165/7150/5905/4928/1487/83746/9631/1788/9112/6045/3619/3090/80012/57122/8517/3183/23511/28996/1655/5970/4792/6996/9612/6672/5111/2099/4927/9883/1387/1616/2033/23512/3066/7157/1107/6256/5371/8924/672/10155/10499/5914/25942/9641/6117/7690/648/4286/4791/4193 51 Human_parvovirus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 11/1519 17/10654 2.5821728197483496e-6 2.4680332965565748e-5 1.5185776079526908e-5 1147/4790/8737/8517/5970/4792/4793/1660/3551/4791/148022 11 Human_parvovirus R-HSA-196299 Beta-catenin phosphorylation cascade 11/1519 17/10654 2.5821728197483496e-6 2.4680332965565748e-5 1.5185776079526908e-5 1499/5525/1452/5519/324/8312/5529/5527/5518/5515/5516 11 Human_parvovirus R-HSA-432142 Platelet sensitization by LDL 11/1519 17/10654 2.5821728197483496e-6 2.4680332965565748e-5 1.5185776079526908e-5 5321/5525/5519/1432/5529/5527/7804/5518/5781/5515/5516 11 Human_parvovirus R-HSA-195258 RHO GTPase Effectors 77/1519 327/10654 3.5479727960713025e-6 3.3667454086460776e-5 2.0715539763506054e-5 85415/3831/5905/84617/4928/25/1495/1499/5525/7531/5747/10093/4627/10971/80152/10458/10382/5594/1027/3619/79172/2810/147179/55920/10381/57122/6280/30851/7534/5048/5501/5216/10552/100527963/10152/6279/6714/5519/10092/8936/1432/4637/10163/999/347733/23081/3895/11243/391/5529/51143/4628/5527/2885/9055/1857/23191/7514/8826/10499/5518/3799/10383/103910/29984/5347/1729/5217/10095/23332/10726/7280/5500/7529/5595/5515/5516 77 Human_parvovirus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 15/1519 30/10654 3.574245549765038e-6 3.3674499143857746e-5 2.071987457796124e-5 7321/7326/8239/7316/7317/7322/8078/7324/6233/7327/7311/27338/7874/7332/7314 15 Human_parvovirus R-HSA-5654738 Signaling by FGFR2 26/1519 73/10654 4.0038517593224366e-6 3.745447142231414e-5 2.3045686498227694e-5 23543/5335/5594/3178/5441/5431/7316/3185/6714/10818/8569/2962/867/6233/2885/3187/7073/7311/5518/3845/5781/5725/7314/5595/5515/5516 26 Human_parvovirus R-HSA-72172 mRNA Splicing 51/1519 191/10654 4.038801724857436e-6 3.751534841610534e-5 2.308314403161663e-5 8449/220988/24148/27339/4904/9879/10523/6428/11325/3184/8106/3178/23450/5441/3183/5431/9092/5093/10594/6625/10713/1655/9343/3185/9416/5546/2962/10236/10189/9295/10949/3181/1660/2521/3191/27316/3187/6634/5094/9775/3192/6427/3312/5725/1479/26121/11100/10992/10262/6628/1994 51 Human_parvovirus R-HSA-4791275 Signaling by WNT in cancer 16/1519 34/10654 4.65558794950863e-6 4.29421014363768e-5 2.6422217954149092e-5 1487/1499/5525/1452/4041/8658/5519/324/8312/5529/5527/1488/5518/80351/5515/5516 16 Human_parvovirus R-HSA-3371571 HSF1-dependent transactivation 13/1519 24/10654 5.131379546460216e-6 4.700201126236822e-5 2.892027507544464e-5 3303/84335/3305/64223/1387/3320/2033/2475/3306/3304/3312/57521/10728 13 Human_parvovirus R-HSA-5675482 Regulation of necroptotic cell death 11/1519 18/10654 5.782704791875981e-6 5.2602673244720134e-5 3.2366354951262306e-5 7186/8737/841/7316/8797/329/6233/7311/8772/8795/7314 11 Human_parvovirus R-HSA-5607764 CLEC7A (Dectin-1) signaling 32/1519 101/10654 5.892594708793814e-6 5.323515356780165e-5 3.275551925364118e-5 1147/8945/5684/4790/387522/7321/5707/5336/3708/5705/841/10197/8517/7316/5695/7335/5970/4792/5714/6714/7322/5708/5686/5534/7189/6233/7311/3710/7334/3551/4791/7314 32 Human_parvovirus R-HSA-5654733 Negative regulation of FGFR4 signaling 15/1519 31/10654 6.015374171520927e-6 5.3974683892762606e-5 3.321055127993294e-5 5594/7316/6714/10818/8569/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 15 Human_parvovirus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 39/1519 134/10654 6.073299089740658e-6 5.412622634708059e-5 3.330379515071158e-5 1147/8945/5684/5601/5335/4790/387522/7321/5707/5336/5594/4214/3708/5705/10197/8517/7316/5695/7335/5970/4792/5714/7322/4067/5708/5686/5534/7189/6233/2885/7410/7311/3710/3845/7334/3551/6416/7314/5595 39 Human_parvovirus R-HSA-6807070 PTEN Regulation 40/1519 140/10654 7.610074215600102e-6 6.736703282131902e-5 4.14508457804852e-5 27161/5684/1822/23186/5707/2146/9112/10273/6045/5594/80012/5705/10197/7316/5695/8658/5714/1108/64223/5928/57459/5708/54815/5686/23512/6009/3066/7157/1107/5371/6233/2475/7311/648/80351/7874/57521/23252/7314/5595 40 Human_parvovirus R-HSA-70171 Glycolysis 25/1519 71/10654 7.724760286102203e-6 6.792639211579204e-5 4.17950188111214e-5 23165/4928/7167/2597/9631/5315/5567/57122/5214/83440/23511/5230/4927/5519/9883/2023/5209/226/5208/5224/5213/5518/5515/5223/5516 25 Human_parvovirus R-HSA-2467813 Separation of Sister Chromatids 50/1519 190/10654 7.79639947262356e-6 6.81023238701356e-5 4.19032693857983e-5 5905/84617/4928/5684/246184/5525/7321/5707/80152/10382/3619/79172/23244/55920/10381/57122/5705/10197/23047/5048/7316/5695/5501/100527963/5714/5519/347733/5708/5686/11243/5529/51143/51529/7324/64682/6233/5527/51434/7514/7311/5518/10383/5347/113130/23332/10726/7280/7314/5515/5516 50 Human_parvovirus R-HSA-187037 Signaling by NTRK1 (TRKA) 27/1519 80/10654 8.421679475127042e-6 7.308023176113532e-5 4.4966169496696324e-5 1173/5335/5899/5604/5594/1785/160/6774/6714/5605/10818/5519/5898/1432/2885/5900/163/6196/5906/5518/1211/3845/6300/7529/5595/5515/5516 27 Human_parvovirus R-HSA-69206 G1/S Transition 38/1519 131/10654 8.671923995278074e-6 7.475991993314888e-5 4.599967939703747e-5 6118/5684/5707/1027/5925/4173/5705/10197/4149/91768/7316/5422/5753/5695/983/5714/5111/4171/4609/5519/6119/5928/6502/5708/5686/595/6233/7311/5518/6117/1719/5001/7465/4176/7314/5515/6241/5516 38 Human_parvovirus R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 13/1519 25/10654 9.297244745621562e-6 7.96302975290574e-5 4.899641626024761e-5 3135/3107/10484/821/811/22872/567/3106/3309/3133/3134/3105/10427 13 Human_parvovirus R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 20/1519 51/10654 9.831036354279961e-6 8.316977100498057e-5 5.1174249586880035e-5 84617/2589/5321/10382/830/10381/23299/5048/22930/1639/832/25782/5870/636/2590/347733/51143/10383/7280/51164 20 Human_parvovirus R-HSA-5673000 RAF activation 15/1519 32/10654 9.836606729929468e-6 8.316977100498057e-5 5.1174249586880035e-5 5604/5525/6714/5605/5519/5529/5894/5527/5518/4140/3845/5245/7529/5515/5516 15 Human_parvovirus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 72/1519 309/10654 1.0812167602974445e-5 9.083598132689996e-5 5.5891258611420036e-5 8945/5684/79754/8065/246184/387522/7321/5707/84231/10273/154881/10533/5705/10197/53339/26263/51619/9690/7326/7323/57630/7316/5695/7317/80196/7335/7337/5714/26118/25831/7322/10489/23327/63893/6502/118424/10616/5708/5686/55294/10422/22954/83737/51529/7324/10075/64682/9246/8924/51191/6233/9520/51434/90025/7327/25793/51343/7311/26091/6047/7318/80204/26232/57520/27338/7334/55182/7332/9820/7314/642/899 72 Human_parvovirus R-HSA-5621481 C-type lectin receptors (CLRs) 40/1519 142/10654 1.1061401525723958e-5 9.234170007867025e-5 5.681772535864872e-5 1147/8945/5684/4790/387522/7321/5707/5567/5336/3708/5705/841/10197/8517/56667/7316/94025/5695/7335/5970/4792/5714/6714/7322/1387/4067/5708/5686/2033/5534/5894/7189/6233/7311/3710/3845/7334/3551/4791/7314 40 Human_parvovirus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 28/1519 86/10654 1.252217773982463e-5 1.0387894615615527e-4 6.391657753991917e-5 25/5335/5747/4651/10093/5336/4627/10458/5594/4644/147179/2209/3708/10552/10152/6714/10092/8936/4650/10163/4067/3320/2885/7410/23191/3710/10095/5595 28 Human_parvovirus R-HSA-5654741 Signaling by FGFR3 17/1519 40/10654 1.2916336229153492e-5 1.064790467890841e-4 6.551641600445621e-5 5335/5594/7316/6714/10818/8569/867/6233/2885/7311/5518/3845/5781/7314/5595/5515/5516 17 Human_parvovirus R-HSA-69231 Cyclin D associated events in G1 18/1519 44/10654 1.3670700969939923e-5 1.1130650974907874e-4 6.848674754921171e-5 25/1027/5925/7316/5753/6714/1871/5519/4067/6502/1021/595/6233/7311/5518/7314/5515/5516 18 Human_parvovirus R-HSA-69236 G1 Phase 18/1519 44/10654 1.3670700969939923e-5 1.1130650974907874e-4 6.848674754921171e-5 25/1027/5925/7316/5753/6714/1871/5519/4067/6502/1021/595/6233/7311/5518/7314/5515/5516 18 Human_parvovirus R-HSA-69239 Synthesis of DNA 35/1519 119/10654 1.3954245827472142e-5 1.12918099671385e-4 6.947835668699402e-5 6118/5684/246184/7321/5707/5982/4173/5705/10197/7316/5422/5695/5425/5714/5111/4171/6119/6502/5708/5985/5686/51529/5984/7324/64682/6233/51434/51343/7311/5983/6117/5001/5981/4176/7314 35 Human_parvovirus R-HSA-5654726 Negative regulation of FGFR1 signaling 15/1519 33/10654 1.5668025540794763e-5 1.2601296151407496e-4 7.753560777890092e-5 5594/7316/6714/10818/8569/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 15 Human_parvovirus R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 22/1519 61/10654 1.7378290939525295e-5 1.389210045408113e-4 8.547790950158854e-5 25/5747/4651/10093/4627/10458/5594/4644/147179/2209/10552/10152/10092/8936/4650/10163/3320/2885/7410/23191/10095/5595 22 Human_parvovirus R-HSA-5688426 Deubiquitination 69/1519 297/10654 1.8223410632441866e-5 1.4479926882042665e-4 8.909479770204618e-5 23358/5684/3607/23326/7186/7321/5707/8737/8237/57506/51720/5705/10197/7706/8517/29086/8239/7316/5695/79155/4792/8658/983/11047/55252/5714/2099/9100/4609/7415/23586/4089/8850/9097/329/7046/6502/4088/8078/5708/5686/324/2033/64135/8312/8473/7157/10869/9958/7189/6233/672/7048/9804/7311/55593/84282/78990/7187/7040/5887/9736/80351/7874/5886/23252/7314/4193/7528 69 Human_parvovirus R-HSA-5654743 Signaling by FGFR4 17/1519 41/10654 1.9155084366984782e-5 1.512907561679816e-4 9.30890012413821e-5 5335/5594/7316/6714/10818/8569/867/6233/2885/7311/5518/3845/5781/7314/5595/5515/5516 17 Human_parvovirus R-HSA-166208 mTORC1-mediated signalling 12/1519 23/10654 1.9823863643037947e-5 1.547199771903376e-4 9.519899637983345e-5 6194/84335/6198/64223/1981/6009/1977/1975/2475/1978/57521/7529 12 Human_parvovirus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 12/1519 23/10654 1.9823863643037947e-5 1.547199771903376e-4 9.519899637983345e-5 5601/387522/8517/7316/7335/3656/7189/6233/7311/7334/6416/7314 12 Human_parvovirus R-HSA-5213460 RIPK1-mediated regulated necrosis 11/1519 20/10654 2.315994766850726e-5 1.7760448241140159e-4 1.092798020343886e-4 7186/8737/841/7316/8797/329/6233/7311/8772/8795/7314 11 Human_parvovirus R-HSA-5218859 Regulated Necrosis 11/1519 20/10654 2.315994766850726e-5 1.7760448241140159e-4 1.092798020343886e-4 7186/8737/841/7316/8797/329/6233/7311/8772/8795/7314 11 Human_parvovirus R-HSA-69186 Lagging Strand Synthesis 11/1519 20/10654 2.315994766850726e-5 1.7760448241140159e-4 1.092798020343886e-4 6118/5982/5422/5425/5111/6119/5985/5984/5983/6117/5981 11 Human_parvovirus R-HSA-3371568 Attenuation phase 9/1519 14/10654 2.417393619305207e-5 1.836202904726172e-4 1.1298132074090251e-4 3303/3305/1387/3320/2033/3306/3304/3312/10728 9 Human_parvovirus R-HSA-187687 Signalling to ERKs 15/1519 34/10654 2.436205521812586e-5 1.836202904726172e-4 1.1298132074090251e-4 5899/5604/5594/6714/5605/10818/5898/1432/2885/5900/5906/3845/6300/7529/5595 15 Human_parvovirus R-HSA-5654727 Negative regulation of FGFR2 signaling 15/1519 34/10654 2.436205521812586e-5 1.836202904726172e-4 1.1298132074090251e-4 5594/7316/6714/10818/8569/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 15 Human_parvovirus R-HSA-69306 DNA Replication 36/1519 127/10654 2.5820355243920008e-5 1.9272024586172623e-4 1.1858051120018431e-4 6118/5684/246184/7321/5707/5982/4173/5705/10197/7316/5422/5695/5425/5714/5111/4171/1871/6119/6502/5708/5985/5686/51529/5984/7324/64682/6233/51434/51343/7311/5983/6117/5001/5981/4176/7314 36 Human_parvovirus R-HSA-9020702 Interleukin-1 signaling 31/1519 103/10654 2.5861625108055754e-5 1.9272024586172623e-4 1.1858051120018431e-4 1147/8945/5684/351/4790/5604/387522/5707/8878/5705/10197/8517/7316/5695/79155/7335/5970/4792/4793/5714/5708/5686/3656/7189/6233/7311/7334/3551/6416/4791/7314 31 Human_parvovirus R-HSA-3247509 Chromatin modifying enzymes 64/1519 274/10654 3.04730856675396e-5 2.2454748600829458e-4 1.3816376977167323e-4 55904/55683/84678/23774/10196/1810/5927/8464/23326/55167/4790/79718/51742/6597/196528/23186/84193/2146/1788/9112/284058/6599/79960/9611/84289/5970/9612/29072/6603/1108/27097/8850/5928/1387/57459/64324/6907/8289/54815/23081/2033/23512/595/6944/8473/3066/1107/79084/23587/57492/23133/22992/80854/58508/10499/23030/55689/3276/51230/6187/10765/4791/55193/54934 64 Human_parvovirus R-HSA-4839726 Chromatin organization 64/1519 274/10654 3.04730856675396e-5 2.2454748600829458e-4 1.3816376977167323e-4 55904/55683/84678/23774/10196/1810/5927/8464/23326/55167/4790/79718/51742/6597/196528/23186/84193/2146/1788/9112/284058/6599/79960/9611/84289/5970/9612/29072/6603/1108/27097/8850/5928/1387/57459/64324/6907/8289/54815/23081/2033/23512/595/6944/8473/3066/1107/79084/23587/57492/23133/22992/80854/58508/10499/23030/55689/3276/51230/6187/10765/4791/55193/54934 64 Human_parvovirus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 12/1519 24/10654 3.451634773961546e-5 2.529281259364044e-4 1.5562633980844166e-4 5606/387522/8517/7316/7335/1432/3656/7189/6233/7311/7334/7314 12 Human_parvovirus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 18/1519 47/10654 3.9655353572949767e-5 2.8898017327470024e-4 1.7780911663125488e-4 79718/892/7316/9611/7091/9612/4609/8850/1387/6907/2033/55294/3066/7088/6233/7311/4851/7314 18 Human_parvovirus R-HSA-70326 Glucose metabolism 28/1519 91/10654 4.0334404829837706e-5 2.9231362621184577e-4 1.798601857941288e-4 23165/4928/7167/2597/9631/5315/5567/57122/5214/83440/23511/5230/10165/4927/5519/9883/2023/5209/226/4190/5208/5224/5213/5518/4191/5515/5223/5516 28 Human_parvovirus R-HSA-2871837 FCERI mediated NF-kB activation 26/1519 82/10654 4.247509871387662e-5 3.0614565685029103e-4 1.883710158665452e-4 1147/8945/5684/4790/387522/7321/5707/5705/10197/8517/7316/5695/7335/5970/4792/5714/7322/4067/5708/5686/7189/6233/7311/7334/3551/7314 26 Human_parvovirus R-HSA-166520 Signaling by NTRKs 30/1519 101/10654 4.5778494301664454e-5 3.281621412168229e-4 2.019177294426962e-4 1173/5335/5899/5604/5594/1785/160/6774/6714/5605/10818/5802/5519/5898/1432/2885/5900/163/6196/5906/5518/1211/581/3845/6300/5781/7529/5595/5515/5516 30 Human_parvovirus R-HSA-190236 Signaling by FGFR 27/1519 87/10654 4.655578375497547e-5 3.3193015552871694e-4 2.0423618364202612e-4 23543/5335/5594/3178/5441/5431/7316/3185/6714/10818/8569/2962/867/6233/2885/3187/7073/7311/5518/3845/5781/5725/7314/161742/5595/5515/5516 27 Human_parvovirus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 23/1519 69/10654 4.826468739952714e-5 3.4226410042998014e-4 2.105946462084631e-4 23165/3303/6118/4928/9631/7531/5594/3308/10049/57122/23511/3305/9532/4927/6119/9883/3309/22824/3306/6117/3304/3312/5595 23 Human_parvovirus R-HSA-3371511 HSF1 activation 8/1519 12/10654 4.8581655369074345e-5 3.426695370684977e-4 2.1084411083341587e-4 6118/7531/1915/7415/6119/3320/6117/10728 8 Human_parvovirus R-HSA-5696398 Nucleotide Excision Repair 32/1519 111/10654 4.9697729073139624e-5 3.4867715238016576e-4 2.1454058855201934e-4 9318/6118/27339/5982/5441/5431/7316/5425/5111/6119/1161/1642/2965/5985/2033/2068/2071/5984/6233/51426/7311/5887/5983/6117/7334/5981/7874/8178/5886/7314/8451/7528 32 Human_parvovirus R-HSA-69190 DNA strand elongation 14/1519 32/10654 5.0993637034920465e-5 3.5587622883100577e-4 2.18970170726392e-4 6118/5982/4173/5422/5425/5111/4171/6119/5985/5984/5983/6117/5981/4176 14 Human_parvovirus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 9/1519 15/10654 5.2775719783817586e-5 3.663746020781863e-4 2.254298058355865e-4 3665/387522/7316/7335/7189/6233/7311/7334/7314 9 Human_parvovirus R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 15/1519 36/10654 5.5198580911472485e-5 3.8118810587556127e-4 2.345445350385522e-4 25/5747/10093/10458/5594/147179/10552/10152/10092/8936/10163/2885/23191/10095/5595 15 Human_parvovirus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 27/1519 88/10654 5.817552544851279e-5 3.996537399301478e-4 2.4590641513598337e-4 3303/5684/5707/3842/3184/3315/26986/5705/10197/7534/7316/5695/5714/1432/5708/5686/55802/1981/6233/7514/7311/51010/3304/3312/7529/7314/1994 27 Human_parvovirus R-HSA-8943724 Regulation of PTEN gene transcription 21/1519 61/10654 5.960495705745287e-5 4.0735201222165976e-4 2.506431518478111e-4 1822/23186/2146/9112/6045/5594/80012/1108/64223/5928/57459/54815/23512/6009/3066/7157/1107/2475/648/57521/5595 21 Human_parvovirus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 32/1519 112/10654 6.02271923375809e-5 4.094828180065423e-4 2.5195423381592445e-4 1147/8945/5684/4790/5707/5336/640/930/3708/5705/10197/8517/7316/5695/5970/4792/4793/5714/4067/29760/5708/5686/5534/5478/6233/2885/7311/3710/3845/3551/973/7314 32 Human_parvovirus R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 26/1519 84/10654 6.723037282615117e-5 4.547531372189405e-4 2.798090010740219e-4 4790/79718/9441/29079/892/168544/1051/6720/688/9611/5970/9612/9968/1387/6907/23389/2033/9967/7026/6256/9477/1879/55588/10499/7040/9969 26 Human_parvovirus R-HSA-5357905 Regulation of TNFR1 signaling 14/1519 33/10654 7.702303497796085e-5 5.183335874282161e-4 3.1892996760476814e-4 1147/7186/8737/55072/841/8517/7316/7132/329/10616/6233/7311/3551/7314 14 Human_parvovirus R-HSA-6802957 Oncogenic MAPK signaling 23/1519 71/10654 7.990253221916823e-5 5.328629817740469e-4 3.2786988463971126e-4 4000/27044/5604/55750/5594/5908/7414/10533/23164/8546/57085/6714/5605/5894/56829/8826/5906/4140/3845/5245/7529/57670/5595 23 Human_parvovirus R-HSA-162906 HIV Infection 55/1519 233/10654 7.99900457856416e-5 5.328629817740469e-4 3.2786988463971126e-4 23165/5905/8945/1173/4928/5684/8065/162/9631/5707/1174/7520/57122/5705/5441/10197/160/5431/23511/7316/293/5695/292/567/51271/5714/4927/8148/2962/23327/9883/8812/8732/5708/2965/5686/27183/905/2068/2071/5902/5478/6233/7514/163/7311/6908/7251/11198/6829/1104/2547/2961/8178/7314 55 Human_parvovirus R-HSA-5685942 HDR through Homologous Recombination (HRR) 22/1519 67/10654 9.042783689763349e-5 5.963715843398928e-4 3.669466434109233e-4 6118/9156/5883/5982/7316/5425/5111/7517/6119/5889/5429/5985/5984/23514/6233/51426/672/7311/5983/6117/5981/7314 22 Human_parvovirus R-HSA-6802952 Signaling by BRAF and RAF fusions 22/1519 67/10654 9.042783689763349e-5 5.963715843398928e-4 3.669466434109233e-4 4000/27044/5604/55750/5594/5908/7414/10533/23164/8546/57085/6714/5605/5894/56829/8826/5906/4140/3845/7529/57670/5595 22 Human_parvovirus R-HSA-5654736 Signaling by FGFR1 18/1519 50/10654 1.0251278993668606e-4 6.727083080919847e-4 4.13916528102566e-4 5335/5594/7316/6714/10818/8569/867/6233/2885/7311/5518/3845/5781/7314/161742/5595/5515/5516 18 Human_parvovirus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 9/1519 16/10654 1.0536639339709374e-4 6.880112519344883e-4 4.23332409114952e-4 7316/7046/6233/7048/7311/56288/7040/57530/7314 9 Human_parvovirus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 13/1519 30/10654 1.0673626187352082e-4 6.935228049811525e-4 4.2672366038104515e-4 1147/7186/8737/55072/8517/7316/7132/329/10616/6233/7311/3551/7314 13 Human_parvovirus R-HSA-209543 p75NTR recruits signalling complexes 8/1519 13/10654 1.1049037111951905e-4 7.143960760129688e-4 4.3956695631139933e-4 5584/8878/7316/7189/6233/7311/3551/7314 8 Human_parvovirus R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 16/1519 42/10654 1.1393981853835432e-4 7.331054665955578e-4 4.510788194766171e-4 51176/8945/1487/1499/7534/7316/7091/9580/607/324/7088/6233/7514/7311/25776/7314 16 Human_parvovirus R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 15/1519 38/10654 1.1589208649922828e-4 7.420469033615636e-4 4.5658047363773634e-4 6597/196528/6045/80012/6599/865/28996/6603/8289/2033/861/57492/648/23429/55193 15 Human_parvovirus R-HSA-73887 Death Receptor Signalling 37/1519 141/10654 1.2169093336039137e-4 7.754122758567933e-4 4.7711014299955126e-4 1147/57142/7186/4790/5584/7531/8737/7204/29/55072/8878/11214/841/8517/6453/7316/5970/4792/23263/8797/50649/9826/7132/329/843/23365/10616/3066/7189/6233/7410/7311/8772/3551/8795/7314/10672 37 Human_parvovirus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 11/1519 23/10654 1.2340197931327526e-4 7.825346668952407e-4 4.814925407415751e-4 246184/7321/7316/983/51529/7324/64682/6233/51434/7311/7314 11 Human_parvovirus R-HSA-1980143 Signaling by NOTCH1 23/1519 73/10654 1.2884687603837412e-4 8.131532511704089e-4 5.003321149614024e-4 79718/892/113878/7316/9611/3714/7091/9612/102/4609/8850/1387/6907/2033/55294/3066/7088/83737/92737/6233/7311/4851/7314 23 Human_parvovirus R-HSA-109581 Apoptosis 44/1519 178/10654 1.3314717321784056e-4 8.362910546396747e-4 5.145687746915042e-4 23368/4000/1828/5684/7186/1499/7531/5747/5707/8737/10971/5594/2810/118/5705/841/10197/7534/7316/5695/6774/5714/8797/8428/329/999/100302736/5708/5686/708/324/5534/7157/6233/6709/7311/8772/581/637/8795/7529/7314/5595/148022 44 Human_parvovirus R-HSA-437239 Recycling pathway of L1 17/1519 47/10654 1.4854401910446743e-4 9.28576119425557e-4 5.713516524297551e-4 1173/84617/7430/10382/5594/1785/10381/160/6714/347733/5962/163/6196/3897/10383/1211/7280 17 Human_parvovirus R-HSA-1236974 ER-Phagosome pathway 25/1519 83/10654 1.5015602090453248e-4 9.342254319484827e-4 5.748276669185429e-4 1147/3135/5684/3107/5707/811/5705/10197/8517/9554/7316/5695/567/5714/3106/9341/5708/5686/6233/7311/3133/3134/3551/3105/7314 25 Human_parvovirus R-HSA-73894 DNA Repair 72/1519 334/10654 1.5751415117353057e-4 9.754045323844452e-4 6.001651126997386e-4 9318/11284/6118/25/3838/4436/151987/9156/5883/27339/7520/51720/2956/5982/51548/9636/5441/7706/23583/5431/5591/29086/7316/2140/11201/6996/5425/5111/9100/10459/7415/7517/6119/51455/1161/5889/1642/5429/2965/5985/2033/2068/54890/2071/7157/55215/5984/23514/9246/8924/6233/51426/672/7311/6047/9025/7318/23030/5536/5887/5983/6117/7334/5981/7874/2547/55666/8178/5886/7314/8451/7528 72 Human_parvovirus R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 13/1519 31/10654 1.599993025824893e-4 9.861639257303897e-4 6.0678535312887e-4 1499/5525/1452/4041/5519/324/8312/5529/5527/1857/5518/5515/5516 13 Human_parvovirus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 19/1519 56/10654 1.650942417400468e-4 0.0010128339760703336 6.231953996649992e-4 3303/5684/5707/3184/3315/26986/5705/10197/7316/5695/5714/5708/5686/1981/6233/7311/3304/3312/7314 19 Human_parvovirus R-HSA-8852135 Protein ubiquitination 24/1519 79/10654 1.7468930373114753e-4 0.0010667369982471464 6.563618575863293e-4 7321/79139/7326/5591/7323/8239/7316/7317/5111/7415/7322/8078/118424/7324/6233/7327/7311/5192/27338/7334/7874/7332/3105/7314 24 Human_parvovirus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 25/1519 84/10654 1.8529400737842216e-4 0.0011262801646642344 6.929986887643148e-4 9318/6118/5982/7316/5425/5111/6119/1642/2965/5985/2068/2071/5984/6233/51426/7311/5887/5983/6117/7334/5981/5886/7314/8451/7528 25 Human_parvovirus R-HSA-388841 Costimulation by the CD28 family 22/1519 70/10654 1.8667839042056856e-4 0.0011294898943336237 6.949736311649366e-4 3120/5525/3117/3119/3123/3115/3122/3113/6714/64223/5519/4067/5529/5527/2885/2475/5518/3127/5781/253260/5515/5516 22 Human_parvovirus R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic 48/1519 202/10654 1.8797395292046508e-4 0.0011321353602835318 6.966013828487316e-4 3831/84617/2589/5321/11014/9265/51014/10382/55275/830/10381/55605/23299/9554/377/5048/9570/22930/22836/1639/832/25782/5870/11316/636/9341/4124/100302736/2590/347733/3482/10972/51143/250/10228/10749/3799/10383/10139/8675/2800/84342/57589/7280/54732/51164/1523/22818 48 Human_parvovirus R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 11/1519 24/10654 1.9861289833714046e-4 0.0011907746041213102 7.326820316647623e-4 6118/5982/5422/5425/5111/6119/5985/5984/5983/6117/5981 11 Human_parvovirus R-HSA-5357801 Programmed Cell Death 44/1519 181/10654 1.9975841324150633e-4 0.0011922232898893522 7.335734060928858e-4 23368/4000/1828/5684/7186/1499/7531/5747/5707/8737/10971/5594/2810/118/5705/841/10197/7534/7316/5695/6774/5714/8797/8428/329/999/100302736/5708/5686/708/324/5534/7157/6233/6709/7311/8772/581/637/8795/7529/7314/5595/148022 44 Human_parvovirus R-HSA-162909 Host Interactions of HIV factors 34/1519 129/10654 2.0597558457117842e-4 0.0012237918740963258 7.529975140084332e-4 23165/5905/8945/1173/4928/5684/8065/162/9631/5707/1174/57122/5705/10197/160/23511/7316/293/5695/292/567/5714/4927/9883/5708/5686/5902/5478/6233/7514/163/7311/1104/7314 34 Human_parvovirus R-HSA-68886 M Phase 82/1519 395/10654 2.1336777021528422e-4 0.0012620273045469053 7.765237235590472e-4 4000/23165/5905/84617/4928/5684/9631/246184/5525/7531/11190/7321/5707/5862/80152/10382/5594/3619/140609/79172/5925/23244/55920/10381/57122/5705/25836/10197/7443/23047/23141/10051/23511/5048/7316/10776/5695/5501/983/1639/100527963/5714/55722/4927/5519/9883/7840/347733/5708/3320/5686/80097/11243/23397/5529/51143/9918/51529/7324/64682/23399/23592/5577/6233/5527/23175/23133/51434/7514/7311/5518/10383/5347/113130/23332/1453/10726/7280/7314/5595/5515/5516 82 Human_parvovirus R-HSA-174411 Polymerase switching on the C-strand of the telomere 8/1519 14/10654 2.25578951021475e-4 0.001310742891618174 8.064983595527812e-4 5982/5422/5425/5111/5985/5984/5983/5981 8 Human_parvovirus R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 8/1519 14/10654 2.25578951021475e-4 0.001310742891618174 8.064983595527812e-4 6118/4436/9156/2956/5425/5111/6119/6117 8 Human_parvovirus R-HSA-69091 Polymerase switching 8/1519 14/10654 2.25578951021475e-4 0.001310742891618174 8.064983595527812e-4 5982/5422/5425/5111/5985/5984/5983/5981 8 Human_parvovirus R-HSA-69109 Leading Strand Synthesis 8/1519 14/10654 2.25578951021475e-4 0.001310742891618174 8.064983595527812e-4 5982/5422/5425/5111/5985/5984/5983/5981 8 Human_parvovirus R-HSA-1236977 Endosomal/Vacuolar pathway 7/1519 11/10654 2.3013824515529316e-4 0.0013309714081409178 8.189449388904255e-4 3135/3107/567/3106/3133/3134/3105 7 Human_parvovirus R-HSA-446652 Interleukin-1 family signaling 36/1519 140/10654 2.310784324975513e-4 0.0013309714081409178 8.189449388904255e-4 1147/8945/5684/351/4790/5604/5782/387522/5707/29110/8878/5705/10197/8517/7316/5695/79155/6774/7335/5970/4792/4793/5714/4088/5708/5686/3656/7189/6233/7311/7334/3551/6416/5781/4791/7314 36 Human_parvovirus R-HSA-449147 Signaling by Interleukins 93/1519 461/10654 2.394317876610353e-4 0.0013730892518474154 8.448599921586189e-4 1147/8945/5897/9655/5684/5601/351/4790/6597/5606/5604/5782/387522/7412/5707/9180/3589/3911/5451/29110/5594/8878/6624/821/5908/3383/5705/301/10197/8517/7534/3662/6776/7316/6175/5695/79155/3185/6774/1435/7335/5970/4792/4793/5714/6772/4609/5519/5898/7132/1432/867/4067/29760/4088/3636/5708/3320/5686/200081/3656/595/3181/7157/6648/5478/7189/6233/2885/3716/604/6196/7311/6809/4507/6888/5518/302/7040/6777/7334/3977/3312/3551/6416/5781/4791/5724/7314/3572/5595/5515/5516 93 Human_parvovirus R-HSA-389513 CTLA4 inhibitory signaling 10/1519 21/10654 2.6424278989400717e-4 0.0015023113787508426 9.243701951373845e-4 5525/6714/5519/4067/5529/5527/5518/5781/5515/5516 10 Human_parvovirus R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 10/1519 21/10654 2.6424278989400717e-4 0.0015023113787508426 9.243701951373845e-4 6118/5982/5425/5111/6119/5985/5984/5983/6117/5981 10 Human_parvovirus R-HSA-2500257 Resolution of Sister Chromatid Cohesion 33/1519 126/10654 2.879711287195408e-4 0.0016301884926226366 0.001003052813384983 5905/84617/4928/5525/80152/10382/3619/79172/23244/55920/10381/57122/23047/5048/5501/983/100527963/5519/347733/11243/5529/51143/5527/7514/5518/10383/5347/113130/23332/10726/7280/5515/5516 33 Human_parvovirus R-HSA-8878166 Transcriptional regulation by RUNX2 32/1519 121/10654 2.925918428574263e-4 0.0016492676954228433 0.0010147922215163099 25/5684/5707/10273/5594/5925/59269/5705/10197/7316/865/5695/983/5714/6772/6714/2099/4089/6502/5708/5686/2101/595/55294/861/6233/7311/25937/581/133522/7314/5595 32 Human_parvovirus R-HSA-210991 Basigin interactions 11/1519 25/10654 3.09255124382409e-4 0.001728421648561006 0.0010634955437057866 9123/483/8140/9057/682/5478/6520/3897/481/6566/3655 11 Human_parvovirus R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 11/1519 25/10654 3.09255124382409e-4 0.001728421648561006 0.0010634955437057866 2305/51400/983/5519/9088/7514/5518/5347/7465/5515/5516 11 Human_parvovirus R-HSA-2559585 Oncogene Induced Senescence 13/1519 33/10654 3.369955357883482e-4 0.0018755152392608914 0.0011540020346116654 5594/5925/7316/2114/1871/1021/7157/6233/7311/2113/7314/5595/4193 13 Human_parvovirus R-HSA-6798695 Neutrophil degranulation 95/1519 480/10654 4.1199016070177116e-4 0.002283256394813597 0.001404884625833992 5869/7077/1828/3303/80331/10890/8621/4790/960/56888/1938/1915/8635/3107/11333/84514/5707/5315/9761/23197/79888/383/5594/6317/7520/5908/7414/10549/10533/54509/4257/6280/1604/1509/5695/6278/4126/5611/567/102/6279/5768/154664/29952/4069/7415/3106/5870/10092/5795/1432/6793/226/8904/100302736/978/55832/5708/3320/5686/3615/3482/391/3728/10555/51143/5478/1143/10075/2683/11031/684/6709/10857/23191/3685/47/8826/5906/89777/302/10383/1729/3608/51806/3304/3312/2547/23250/2665/7879/5724/1508/114790/5223 95 Human_parvovirus R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 8/1519 15/10654 4.230683581502255e-4 0.0023251131850006144 0.001430639053218526 29110/81844/7316/22954/3661/6233/7311/7314 8 Human_parvovirus R-HSA-5358508 Mismatch Repair 8/1519 15/10654 4.230683581502255e-4 0.0023251131850006144 0.001430639053218526 6118/4436/9156/2956/5425/5111/6119/6117 8 Human_parvovirus R-HSA-162599 Late Phase of HIV Life Cycle 35/1519 139/10654 4.3036417553476644e-4 0.0023553956329060454 0.001449271803176698 23165/5905/4928/9631/57122/5441/5431/23511/7316/51271/4927/8148/2962/23327/9883/8812/8732/2965/27183/905/2068/2071/5902/5478/6233/7514/7311/6908/7251/11198/6829/1104/2961/8178/7314 35 Human_parvovirus R-HSA-453274 Mitotic G2-G2/M phases 46/1519 198/10654 4.344246187904171e-4 0.0023677936867130584 0.0014569003092101418 8945/84617/5684/2305/7531/11190/5707/10382/51400/10381/5705/10197/5048/7316/5695/983/1639/5714/55722/1871/5519/9088/5928/7840/347733/5708/3320/5686/80097/2033/7157/5577/6233/7514/7311/5518/10383/5347/23332/1453/7465/7280/5500/7314/5515/5516 46 Human_parvovirus R-HSA-180024 DARPP-32 events 11/1519 26/10654 4.674963737565877e-4 0.0025375626213371984 0.001561358909102574 5575/5567/5519/5534/5499/5577/5144/5518/5141/5515/5516 11 Human_parvovirus R-HSA-170968 Frs2-mediated activation 7/1519 12/10654 4.843174708560013e-4 0.0025968079026791285 0.0015978124519896322 5604/5594/5605/10818/5906/7529/5595 7 Human_parvovirus R-HSA-5689877 Josephin domain DUBs 7/1519 12/10654 4.843174708560013e-4 0.0025968079026791285 0.0015978124519896322 7316/7415/6233/7311/5887/5886/7314 7 Human_parvovirus R-HSA-9634600 Regulation of glycolysis by fructose 2,6-bisphosphate metabolism 7/1519 12/10654 4.843174708560013e-4 0.0025968079026791285 0.0015978124519896322 5567/5519/5209/5208/5518/5515/5516 7 Human_parvovirus R-HSA-5663220 RHO GTPases Activate Formins 35/1519 140/10654 4.967927565471701e-4 0.002652913546096022 0.0016323341798332332 5905/84617/4928/5525/80152/10382/3619/79172/55920/10381/57122/5048/5501/5216/100527963/6714/5519/347733/11243/5529/51143/5527/1857/7514/5518/10383/29984/5347/1729/5217/23332/10726/7280/5515/5516 35 Human_parvovirus R-HSA-1236975 Antigen processing-Cross presentation 27/1519 99/10654 5.013951693495228e-4 0.0026666944692420183 0.0016408135635334554 1147/3135/5684/3107/5707/811/2209/5705/10197/8517/9554/7316/5695/567/5714/3106/9341/5708/5686/6233/3685/7311/3133/3134/3551/3105/7314 27 Human_parvovirus R-HSA-73762 RNA Polymerase I Transcription Initiation 16/1519 47/10654 5.102793032522152e-4 0.002703045787107116 0.0016631804811137517 9112/5441/51082/7343/1108/8850/5928/57459/2965/54815/2068/3066/2071/1107/84172/6908 16 Human_parvovirus R-HSA-400253 Circadian Clock 21/1519 70/10654 5.25395932592172e-4 0.0027719889403562993 0.0017056011116992195 5187/8945/1374/79718/200186/6720/7316/9611/5501/64784/1387/6907/2033/6256/5499/6233/7311/10499/1453/5500/7314 21 Human_parvovirus R-HSA-8878171 Transcriptional regulation by RUNX1 53/1519 239/10654 5.548135170364564e-4 0.002915533979964486 0.0017939241838335416 55904/27161/25/5684/6597/196528/6929/5707/640/6045/80012/6938/5705/10197/6599/7316/865/5695/28996/5079/6603/2623/5714/6714/2099/8850/1387/8289/5708/5686/2033/1021/595/4602/8312/83737/861/1998/5371/57492/6233/7311/6688/58508/25942/648/3276/3977/5781/23429/1997/55193/7314 53 Human_parvovirus R-HSA-5696395 Formation of Incision Complex in GG-NER 15/1519 43/10654 5.645218092762125e-4 0.002937011342114041 0.0018071391762259493 6118/7316/6119/1642/2965/2068/2071/6233/7311/5887/6117/7334/5886/7314/8451 15 Human_parvovirus R-HSA-75893 TNF signaling 15/1519 43/10654 5.645218092762125e-4 0.002937011342114041 0.0018071391762259493 1147/7186/8737/55072/841/8517/7316/7132/329/10616/6233/7311/8772/3551/7314 15 Human_parvovirus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 9/1519 19/10654 5.678073481721611e-4 0.002937011342114041 0.0018071391762259493 5335/7316/867/3320/6233/2885/7311/3845/7314 9 Human_parvovirus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 9/1519 19/10654 5.678073481721611e-4 0.002937011342114041 0.0018071391762259493 5335/7316/867/3320/6233/2885/7311/3845/7314 9 Human_parvovirus R-HSA-8951664 Neddylation 52/1519 234/10654 5.914818397621287e-4 0.0030475177603369054 0.0018751336285222093 9318/8945/56995/9655/5684/79754/8065/25879/7321/5707/154881/28952/5705/55827/10197/53339/26263/7323/7316/5695/5714/26118/7322/10489/23369/1161/6502/90864/55832/5708/1642/5686/55294/79269/10238/23142/10116/6233/25793/7311/83987/2034/80204/26232/51667/54939/8816/150684/9820/7314/8451/899 52 Human_parvovirus R-HSA-69481 G2/M Checkpoints 40/1519 168/10654 5.972667998190571e-4 0.0030653498403164837 0.0018861056836391278 6118/5684/9156/5883/7531/5707/10971/51720/5982/2810/4173/5705/10197/7534/29086/7316/5695/983/5714/4171/9088/6119/5708/5985/5686/7157/5984/8924/6233/672/7311/9025/5983/6117/7334/5001/7465/4176/7529/7314 40 Human_parvovirus R-HSA-162587 HIV Life Cycle 37/1519 152/10654 6.041986174713645e-4 0.003088906885444689 0.0019006003022049049 23165/5905/4928/9631/7520/57122/5441/5431/23511/7316/51271/4927/8148/2962/23327/9883/8812/8732/2965/27183/905/2068/2071/5902/5478/6233/7514/7311/6908/7251/11198/6829/1104/2547/2961/8178/7314 37 Human_parvovirus R-HSA-69275 G2/M Transition 45/1519 196/10654 6.530782358159694e-4 0.0033259080812404 0.0020464268230608105 8945/84617/5684/2305/7531/11190/5707/10382/51400/10381/5705/10197/5048/7316/5695/983/1639/5714/55722/5519/9088/5928/7840/347733/5708/3320/5686/80097/2033/7157/5577/6233/7514/7311/5518/10383/5347/23332/1453/7465/7280/5500/7314/5515/5516 45 Human_parvovirus R-HSA-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle 13/1519 35/10654 6.582934227638595e-4 0.0033395731716366565 0.0020548349350240315 79139/9761/821/811/7316/5589/7415/6400/6233/7311/5887/267/7314 13 Human_parvovirus R-HSA-70268 Pyruvate metabolism 12/1519 31/10654 6.857413975936197e-4 0.003465490051440553 0.0021323114238543293 3945/9123/25874/5160/1737/3939/5467/682/55066/6256/2739/6566 12 Human_parvovirus R-HSA-392517 Rap1 signalling 8/1519 16/10654 7.407703229033579e-4 0.003715118083306194 0.0022859072201660557 23108/5567/5908/7534/6494/5894/5906/7529 8 Human_parvovirus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 8/1519 16/10654 7.407703229033579e-4 0.003715118083306194 0.0022859072201660557 7316/100302736/3656/7189/6233/7311/7314/148022 8 Human_parvovirus R-HSA-1169091 Activation of NF-kappaB in B cells 20/1519 67/10654 7.587471615019953e-4 0.00379086176523156 0.0023325122070097224 1147/8945/5684/4790/5707/5705/10197/8517/7316/5695/5970/4792/4793/5714/5708/5686/6233/7311/3551/7314 20 Human_parvovirus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 21/1519 72/10654 7.934758150395209e-4 0.003949413585045766 0.0024300689310644314 5684/246184/7321/5707/5705/10197/7316/5695/5714/6502/5708/5686/51529/7324/64682/6233/51434/51343/7311/5347/7314 21 Human_parvovirus R-HSA-69618 Mitotic Spindle Checkpoint 29/1519 112/10654 7.997592801276242e-4 0.003965723648452392 0.0024401044914064036 5905/4928/246184/5525/7321/80152/3619/79172/55920/57122/5048/5501/100527963/5519/11243/5529/51143/51529/7324/64682/5527/51434/7514/5518/5347/23332/10726/5515/5516 29 Human_parvovirus R-HSA-8856688 Golgi-to-ER retrograde transport 33/1519 133/10654 8.172836773135078e-4 0.003997866543972722 0.002459881972309939 3831/84617/2589/5321/11014/51014/10382/830/10381/55605/23299/9554/377/5048/22930/1639/832/25782/5870/11316/636/100302736/2590/347733/10972/51143/10749/3799/10383/7280/54732/51164/22818 33 Human_parvovirus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 22/1519 77/10654 8.183956207470878e-4 0.003997866543972722 0.002459881972309939 84617/5684/5707/10382/10381/5705/10197/7316/5695/983/5714/347733/5708/3320/5686/7157/6233/7311/10383/5347/7280/7314 22 Human_parvovirus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 18/1519 58/10654 8.274583521641798e-4 0.003997866543972722 0.002459881972309939 79718/892/7316/9611/3714/9612/102/4609/8850/1387/6907/2033/55294/3066/6233/7311/4851/7314 18 Human_parvovirus R-HSA-2644603 Signaling by NOTCH1 in Cancer 18/1519 58/10654 8.274583521641798e-4 0.003997866543972722 0.002459881972309939 79718/892/7316/9611/3714/9612/102/4609/8850/1387/6907/2033/55294/3066/6233/7311/4851/7314 18 Human_parvovirus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 18/1519 58/10654 8.274583521641798e-4 0.003997866543972722 0.002459881972309939 79718/892/7316/9611/3714/9612/102/4609/8850/1387/6907/2033/55294/3066/6233/7311/4851/7314 18 Human_parvovirus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 18/1519 58/10654 8.274583521641798e-4 0.003997866543972722 0.002459881972309939 79718/892/7316/9611/3714/9612/102/4609/8850/1387/6907/2033/55294/3066/6233/7311/4851/7314 18 Human_parvovirus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 18/1519 58/10654 8.274583521641798e-4 0.003997866543972722 0.002459881972309939 79718/892/7316/9611/3714/9612/102/4609/8850/1387/6907/2033/55294/3066/6233/7311/4851/7314 18 Human_parvovirus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 19/1519 63/10654 8.871818528982591e-4 0.0042707768758131525 0.002627803336859615 5684/246184/7321/5707/5705/10197/7316/5695/5714/5708/5686/51529/7324/64682/6233/51434/51343/7311/7314 19 Human_parvovirus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 13/1519 36/10654 8.975155980381162e-4 0.004304811177499182 0.0026487445974636846 5604/5594/5908/7414/6714/5605/5894/8826/5906/4140/3845/7529/5595 13 Human_parvovirus R-HSA-8876384 Listeria monocytogenes entry into host cells 9/1519 20/10654 9.026190384776573e-4 0.004313603303449384 0.0026541543808782375 1499/7316/6714/867/999/6233/2885/7311/7314 9 Human_parvovirus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 92/1519 473/10654 9.101398010652998e-4 0.00433384259063224 0.002666607587388737 1173/3643/8065/23543/5335/5899/1495/5604/1499/6461/5747/5782/5567/10273/3911/10458/5594/1785/3315/5908/3178/51741/3708/5441/58513/1289/160/5431/6776/7316/5753/9611/3185/6774/102/10152/6772/6714/2099/5605/10818/64223/8569/5802/2962/5519/5898/8936/5795/1432/867/10163/4067/3320/64759/3728/83737/6233/2885/3187/7410/5774/2475/5900/23191/3685/163/7073/6196/7311/5906/5518/1729/3710/1211/581/9564/3845/6777/6300/5781/3480/10603/5725/1291/7529/7314/253260/161742/5595/5515/5516 92 Human_parvovirus R-HSA-5693532 DNA Double-Strand Break Repair 39/1519 166/10654 9.138039907014875e-4 0.004335638358759935 0.002667712521131567 6118/25/3838/151987/9156/5883/7520/51720/5982/51548/5591/29086/7316/2140/5425/5111/7517/6119/5889/5429/5985/7157/5984/23514/8924/6233/51426/672/7311/6047/9025/23030/5536/5983/6117/7334/5981/2547/7314 39 Human_parvovirus R-HSA-171007 p38MAPK events 7/1519 13/10654 9.204490872152302e-4 0.004335972664417459 0.002667918218958431 5899/6714/5898/1432/5900/3845/6300 7 Human_parvovirus R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 7/1519 13/10654 9.204490872152302e-4 0.004335972664417459 0.002667918218958431 7531/10971/2810/7534/983/7465/7529 7 Human_parvovirus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 12/1519 32/10654 9.564369603228758e-4 0.004489467440092075 0.0027623633504736365 892/7316/4609/4089/60436/8812/4088/905/6233/7311/25937/7314 12 Human_parvovirus R-HSA-8939902 Regulation of RUNX2 expression and activity 21/1519 73/10654 9.669571319724605e-4 0.004522753393871189 0.002782844153604954 5684/5707/10273/59269/5705/10197/7316/865/5695/5714/6772/2099/6502/5708/5686/2101/55294/6233/7311/133522/7314 21 Human_parvovirus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 23/1519 83/10654 0.0010015540647724341 0.0046680205351054445 0.002872226832581539 1147/8945/5684/4790/5707/5705/10197/8517/7316/5695/5970/4792/4793/5714/5708/5686/5534/5478/6233/7311/3845/3551/7314 23 Human_parvovirus R-HSA-68877 Mitotic Prometaphase 45/1519 200/10654 0.0010233507933951563 0.00475281583270497 0.0029244012665221118 5905/84617/4928/5525/7531/11190/80152/10382/3619/79172/23244/55920/10381/57122/23047/10051/5048/5501/983/1639/100527963/55722/5519/7840/347733/3320/80097/11243/23397/5529/51143/9918/5577/5527/7514/5518/10383/5347/113130/23332/1453/10726/7280/5515/5516 45 Human_parvovirus R-HSA-110056 MAPK3 (ERK1) activation 6/1519 10/10654 0.0010428611614361999 0.004792800947506438 0.0029490040545289207 5604/983/3716/5781/3572/5595 6 Human_parvovirus R-HSA-2465910 MASTL Facilitates Mitotic Progression 6/1519 10/10654 0.0010428611614361999 0.004792800947506438 0.0029490040545289207 10776/983/5519/5518/5515/5516 6 Human_parvovirus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 6/1519 10/10654 0.0010428611614361999 0.004792800947506438 0.0029490040545289207 7316/3656/7189/6233/7311/7314 6 Human_respiratory_syncytial_virus_B R-HSA-983169 Class I MHC mediated antigen processing & presentation 291/1832 371/10654 5.850011909579753e-155 7.727865732554854e-152 3.953376469421265e-152 8454/9354/23643/57154/1147/3135/197131/23352/26224/8945/4688/10293/51088/140460/5684/79754/6737/8065/64410/127544/114088/11065/285231/221687/9666/84937/57531/142678/55070/84708/246184/146330/55819/51320/93611/7319/54850/142686/8916/79791/26046/151636/3107/7321/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/8697/10484/7320/26235/10477/9817/10193/6890/148581/9039/223082/92912/154881/140739/821/25897/6500/6478/150726/390594/811/10533/81559/144699/140462/26259/57674/51130/10333/7099/53339/8517/154214/7336/200845/4615/79876/26263/64750/51619/6477/9690/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/10213/9604/9978/22888/23304/7317/80196/114907/140456/64718/54926/4008/7335/84861/7096/11059/55236/899/84085/55958/54620/4734/84078/7337/26272/84676/140691/27252/51444/7704/8651/3106/3093/26118/222235/51433/25831/7322/5715/64219/10489/23327/9867/26249/140458/55905/5701/5688/55336/26270/143279/51465/63893/89122/6502/23291/118424/10616/929/3309/27246/89910/55521/114609/25898/9903/201456/55294/26190/55008/7328/79654/5710/10422/84727/135892/7428/22954/8453/401036/83737/51529/9040/695/90933/140461/7324/63891/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/6233/90135/56658/9870/51434/6468/26267/948/142685/1520/4012/5716/25847/90025/7327/3685/10425/25793/51343/7311/26091/23295/6047/84541/3133/7318/23194/51666/90293/131405/55175/55284/3134/868/54461/9320/136371/80204/26232/29882/57520/26234/127247/27338/92591/7334/5930/11275/55182/7097/84961/4591/3551/23014/29116/26268/92369/1536/115290/7332/90678/51725/140459/3105/5696/997/23608/51676/55585/64320/51132/84261/7325/57542/9820/55658/7314/996/4360/10324/283807/1514 291 Human_respiratory_syncytial_virus_B R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 261/1832 309/10654 5.286704733209402e-154 3.49186847628481e-151 1.786349704589703e-151 8454/9354/57154/197131/23352/26224/8945/10293/51088/140460/5684/79754/6737/8065/64410/127544/114088/11065/285231/221687/9666/84937/57531/142678/55070/84708/246184/146330/55819/51320/93611/7319/54850/142686/8916/79791/26046/151636/7321/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/8697/7320/26235/10477/9817/10193/148581/9039/223082/92912/154881/140739/25897/6500/6478/150726/390594/10533/81559/144699/140462/26259/57674/51130/53339/154214/7336/200845/79876/26263/64750/51619/6477/9690/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/10213/9604/9978/22888/23304/7317/80196/114907/140456/64718/54926/4008/7335/84861/11059/55236/899/84085/55958/54620/4734/84078/7337/26272/84676/140691/27252/51444/7704/8651/3093/26118/222235/51433/25831/7322/5715/64219/10489/23327/9867/26249/140458/55905/5701/5688/55336/26270/143279/51465/63893/89122/6502/23291/118424/10616/27246/89910/55521/25898/9903/201456/55294/26190/55008/7328/79654/5710/10422/84727/135892/7428/22954/8453/401036/83737/51529/9040/90933/140461/7324/63891/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/6233/90135/56658/9870/51434/6468/26267/142685/4012/5716/25847/90025/7327/10425/25793/51343/7311/26091/23295/6047/84541/7318/23194/51666/90293/131405/55175/55284/868/54461/9320/136371/80204/26232/29882/57520/26234/127247/27338/92591/7334/5930/11275/55182/84961/4591/23014/29116/26268/92369/115290/7332/90678/51725/140459/5696/997/23608/51676/55585/64320/51132/84261/7325/57542/9820/55658/7314/996/10324/283807 261 Human_respiratory_syncytial_virus_B R-HSA-8951664 Neddylation 171/1832 234/10654 3.5802384213110223e-81 1.5764983181839534e-78 8.064958128005881e-79 8454/9318/51397/26224/54165/8945/56995/23412/51088/9655/140460/5684/79754/8065/64410/149951/29099/285231/23363/23038/146330/25879/93611/54850/142686/55884/79791/7321/51665/9616/122769/9021/4738/26235/9817/9039/154881/140739/6500/150726/3091/390594/144699/140462/28952/26259/51130/53339/28991/200845/26263/140825/8452/8450/7323/9306/10517/89890/142689/7316/10213/9978/114907/140456/4008/84861/64708/899/84085/55958/54620/84078/55527/26272/27252/7704/26118/222235/10980/7322/5715/122416/10489/26249/140458/5701/5688/55336/26270/6502/7347/23291/170622/90864/55832/10920/9903/201456/55294/26190/5710/84727/10987/7428/8453/123879/401036/9040/140461/79176/80176/8139/23142/126433/10116/6233/90135/6468/2873/26267/142685/5716/25793/7311/1154/84541/23194/83987/51666/2034/90293/55175/8533/54461/136371/80204/26232/8835/26234/127247/8883/92591/51667/11275/51122/84961/54939/23014/26268/92369/115290/54951/51725/140459/55208/84259/5696/51676/84261/150684/50813/57542/9820/7314/51514/10537/51138/10324/8451/56929/283807 171 Human_respiratory_syncytial_virus_B R-HSA-168898 Toll-like Receptor Cascades 121/1832 155/10654 5.321383957102055e-63 1.7573870518329535e-60 8.990338159103997e-61 54106/8454/23643/1147/3665/23098/3725/11035/4064/8945/1326/10695/351/81793/4790/6885/5606/11213/7184/7321/8737/10392/653509/8767/5336/3684/1849/29110/5594/6271/1785/4214/6500/330/51295/23118/6280/10333/841/7099/8517/4615/7098/7100/338/5528/7323/7316/79155/7335/1513/5970/4792/7096/59307/4793/6279/177/5641/8651/26052/3146/7322/5519/64127/5598/1432/329/23291/2244/929/114609/3656/10454/3661/695/3654/7189/6285/6233/51311/10010/948/1520/2266/51135/1385/81622/2353/7311/1759/5518/2243/7187/1386/8772/9641/6197/5599/353376/5600/7334/7097/3929/3551/6416/5781/5608/3689/9450/4791/51231/1508/51284/7314/5595/5515/148022/257397/1514/5516 121 Human_respiratory_syncytial_virus_B R-HSA-449147 Signaling by Interleukins 221/1832 461/10654 3.839652298445138e-55 1.0144361372492054e-52 5.189593211793219e-53 5295/729230/8454/3605/7124/1147/2308/834/10148/3725/5777/8945/1326/596/9655/5684/351/3635/3592/5290/3566/1437/3667/4790/6885/6597/5606/2309/90865/5291/4215/3561/11213/3587/7412/7184/10392/8767/3593/5803/6775/207/5292/3684/9021/1849/7422/29110/3553/1230/1439/5594/8878/3595/54472/4582/2919/821/6500/5743/3091/941/23118/25930/4318/3383/4478/8517/1438/6778/3576/4615/3313/3662/3597/6776/5528/2357/1436/7316/3565/4985/10213/6175/9978/2920/3560/79155/6352/6774/920/1435/7335/5970/4792/1441/3055/6850/1026/6348/59307/3718/1440/4793/3627/7133/3606/177/6772/8651/4609/3146/6647/149233/6364/5715/5519/64127/8503/5598/3552/1432/5701/867/5688/6950/3558/4067/3717/29760/23291/4088/3636/598/836/3320/4843/2335/2534/3656/9466/5771/5710/3458/10454/998/7157/5478/942/3654/3563/7189/163702/6285/6233/2885/7525/1398/7006/948/6844/3716/5716/85480/7409/51135/8660/1385/2353/282618/7311/3594/1154/6347/3932/3575/5293/5518/2185/1386/5296/3687/3588/51561/3570/6197/8835/5599/5600/7431/6777/7334/5008/3312/1399/3559/3929/3551/246778/6773/7297/6416/5781/5608/3569/3162/5062/4170/3689/5696/3586/4791/3554/51231/7314/3572/3596/5595/5515/257397/5516 221 Human_respiratory_syncytial_virus_B R-HSA-913531 Interferon Signaling 132/1832 199/10654 1.6314661724751175e-54 3.591944689732717e-52 1.8375461100509217e-52 3135/3443/23165/3665/3460/5777/3837/3441/5903/6737/51447/10379/5335/55706/7175/960/5770/9631/3455/7412/3107/10410/2316/2633/9021/85363/54739/9830/4600/348995/9636/79023/2537/3383/57122/23636/11274/8638/3449/25820/7706/2634/3444/10762/3662/23511/7316/3122/3394/53371/3663/8519/3664/103/4734/3434/6672/3113/6772/8651/23279/4927/9688/3433/3659/3106/79902/23586/6041/3459/25939/1958/9883/4939/6059/3451/3717/23225/3448/1981/3440/5771/3458/3454/3661/3669/8086/7324/3836/9246/5371/3439/51191/4599/6233/5580/684/3716/7311/81603/9972/3133/7318/3429/5610/10581/3134/5300/8021/3452/4940/91543/3437/129401/7334/3456/6773/4938/7297/5781/4261/3430/55746/3105/5696/3660/3446/8480/7314/3445/5595/8554 132 Human_respiratory_syncytial_virus_B R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 100/1832 129/10654 1.2384576097228591e-51 2.33714643206271e-49 1.1956237375068805e-49 8454/23643/1147/3665/23098/3725/11035/4064/8945/1326/351/4790/6885/5606/11213/7321/8737/10392/653509/8767/5336/3684/1849/29110/5594/1785/4214/6500/330/51295/23118/10333/841/7099/8517/4615/5528/7323/7316/79155/7335/5970/4792/7096/59307/4793/177/8651/26052/3146/7322/5519/64127/5598/1432/329/23291/929/114609/3656/10454/3661/695/3654/7189/6285/6233/10010/948/51135/1385/2353/7311/1759/5518/7187/1386/8772/9641/6197/5599/353376/5600/7334/7097/3929/3551/6416/5781/5608/3689/9450/4791/51231/7314/5595/5515/148022/257397/5516 100 Human_respiratory_syncytial_virus_B R-HSA-909733 Interferon alpha/beta signaling 67/1832 69/10654 3.5223793294023125e-49 5.816328867675569e-47 2.975483591416164e-47 3135/3443/3665/5777/3441/51447/10379/5770/3455/3107/10410/9021/54739/4600/9636/2537/11274/8638/3449/2634/3444/3662/3394/3663/8519/3664/103/3434/6772/8651/3433/3659/3106/6041/25939/1958/4939/6059/3451/3448/3440/3454/3661/3669/3439/4599/684/3716/3133/3429/10581/3134/3452/4940/91543/3437/3456/6773/4938/7297/5781/3430/3105/5696/3660/3446/3445 67 Human_respiratory_syncytial_virus_B R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 70/1832 78/10654 5.5555519301803624e-45 8.154315666409176e-43 4.171537238802097e-43 1147/3443/3665/3441/351/7186/4790/80143/7321/8737/9140/29110/57506/79132/4214/9636/54476/3449/841/7706/8517/3444/84166/7323/9474/7316/5970/4792/4793/177/3093/3146/23586/7322/7128/1387/3451/843/3448/2033/64135/3440/54941/83737/3661/9246/7189/3439/6285/51191/6233/10010/7311/55593/84282/7318/79671/5094/7187/8772/5300/3452/9641/1540/3551/3456/4791/3446/7314/3445 70 Human_respiratory_syncytial_virus_B R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 115/1832 185/10654 2.835992485264011e-43 3.7463460730337587e-41 1.9165338689889422e-41 6158/5393/9136/6138/6144/2091/6203/55127/9349/55813/8602/6206/6194/6191/6128/51121/6132/6147/25879/8568/6129/23404/6217/10436/6222/9277/81887/6176/84128/6152/6136/56902/10528/84135/27340/6125/57050/6224/6146/6141/88745/51602/6202/51096/6232/134430/6160/55272/6155/92856/6175/6218/65083/5394/9724/6209/6193/6231/6229/6165/6130/6142/6204/11056/6228/23521/23481/54555/9790/51077/117246/10171/5822/55720/10199/6143/6124/6207/10969/6139/6233/25926/23160/7311/6223/25873/83732/27341/3921/6188/6189/10607/11103/26354/6135/6201/51202/9045/57647/6187/4691/6168/6208/54512/6157/6137/10885/22984/10813/79050/6122/6133/22894/9188/6230 115 Human_respiratory_syncytial_virus_B R-HSA-3371556 Cellular response to heat stress 74/1832 89/10654 1.979245647240638e-42 2.3768940909135298e-40 1.215957612945923e-40 23165/3303/6118/6782/5903/573/55706/7175/9631/1915/116835/5594/9530/3308/84335/10049/348995/1410/10013/545/79023/472/57122/23636/3337/3313/10808/10762/23511/3305/53371/9532/23279/4927/9688/7415/79902/64223/6119/9883/2932/1387/3281/259217/23225/3310/3309/3320/2033/7266/6767/9531/8086/22824/3326/2475/3306/27000/9972/23411/8021/9529/6117/129401/3304/3312/3297/57521/55746/2288/8480/10728/51182/5595 74 Human_respiratory_syncytial_virus_B R-HSA-168255 Influenza Life Cycle 98/1832 144/10654 3.938028648462704e-42 4.33511320384936e-40 2.217731923081628e-40 6158/23165/3303/6138/6144/3837/6203/5903/9349/6206/6194/6191/55706/7175/6128/51121/6132/9631/6147/6129/6217/5430/6222/6176/6152/6136/6125/821/811/6224/6146/348995/6141/6202/79023/57122/23636/6232/10762/5431/6160/23511/6155/6175/6218/53371/5611/6209/6193/23279/4927/6231/6229/9688/6165/79902/6130/2962/6142/6204/9883/6228/5437/23521/23225/3320/6143/6124/6207/8086/3836/6139/6233/7514/7311/6223/25873/9972/1213/3921/6188/6189/8021/6135/6201/129401/3304/9045/6187/55746/6168/6208/6157/6137/8480/6122/6133/6230 98 Human_respiratory_syncytial_virus_B R-HSA-8868773 rRNA processing in the nucleus and cytosol 116/1832 195/10654 6.842563366471743e-41 6.953097082391671e-39 3.5570248431375375e-39 6158/5393/9136/6138/6144/2091/6203/55127/9349/55813/8602/6206/6194/6191/6128/51121/6132/6147/25879/8568/6129/23404/6217/10436/6222/9277/81887/6176/84128/6152/6136/56902/10528/84135/27340/6125/57050/6224/6146/6141/88745/51602/6202/51096/6232/134430/6160/55272/6155/92856/6175/6218/65083/5394/9724/6209/6193/6231/6229/6165/6130/6142/6204/1736/11056/6228/23521/23481/54555/9790/51077/117246/10171/5822/55720/10199/6143/6124/6207/10969/6139/6233/25926/23160/7311/6223/25873/83732/27341/3921/6188/6189/10607/11103/26354/6135/6201/51202/9045/57647/6187/4691/6168/6208/54512/6157/6137/10885/22984/10813/79050/6122/6133/22894/9188/6230 116 Human_respiratory_syncytial_virus_B R-HSA-168254 Influenza Infection 101/1832 155/10654 8.722391832836867e-41 8.230199722269645e-39 4.2103575614144876e-39 6158/23165/3303/6138/6144/3837/6203/5903/9349/6206/6194/6191/55706/7175/6128/51121/6132/9631/6147/6129/6217/5430/6222/6176/6152/6136/8106/6125/821/811/6224/6146/348995/6141/9636/6202/79023/57122/23636/6232/10762/5431/6160/23511/6155/6175/6218/53371/5611/6209/6193/23279/4927/6231/6229/9688/6165/79902/6130/2962/6142/6204/9883/6228/5437/23521/23225/3320/6143/6124/6207/8086/3836/6139/6233/7514/7311/6223/25873/9972/1213/5610/3921/6188/6189/8021/6135/6201/129401/3304/9045/6187/55746/6168/6208/6157/6137/8480/6122/6133/6230 101 Human_respiratory_syncytial_virus_B R-HSA-166166 MyD88-independent TLR4 cascade 77/1832 99/10654 3.888900115597671e-40 3.210773157940327e-38 1.6425486014563844e-38 8454/23643/1147/3665/23098/3725/11035/8945/1326/351/4790/6885/5606/7321/8737/10392/8767/1849/29110/5594/6500/330/23118/841/7099/8517/5528/7323/7316/79155/7335/5970/4792/4793/177/3146/7322/5519/64127/5598/1432/329/23291/929/3656/10454/3661/3654/7189/6285/6233/10010/1385/2353/7311/5518/7187/1386/8772/9641/6197/5599/353376/5600/7334/3551/6416/5781/5608/4791/51231/7314/5595/5515/148022/257397/5516 77 Human_respiratory_syncytial_virus_B R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 77/1832 99/10654 3.888900115597671e-40 3.210773157940327e-38 1.6425486014563844e-38 8454/23643/1147/3665/23098/3725/11035/8945/1326/351/4790/6885/5606/7321/8737/10392/8767/1849/29110/5594/6500/330/23118/841/7099/8517/5528/7323/7316/79155/7335/5970/4792/4793/177/3146/7322/5519/64127/5598/1432/329/23291/929/3656/10454/3661/3654/7189/6285/6233/10010/1385/2353/7311/5518/7187/1386/8772/9641/6197/5599/353376/5600/7334/3551/6416/5781/5608/4791/51231/7314/5595/5515/148022/257397/5516 77 Human_respiratory_syncytial_virus_B R-HSA-72312 rRNA processing 118/1832 205/10654 1.4347827710669206e-39 1.1149106121055306e-37 5.703594668885219e-38 6158/5393/9136/6138/6144/2091/6203/55127/9349/55813/8602/6206/6194/6191/6128/51121/6132/6147/25879/8568/6129/23404/6217/3028/10436/6222/9277/81887/6176/84128/6152/6136/56902/10528/84135/27340/6125/57050/6224/6146/6141/88745/51602/6202/51096/6232/134430/6160/55272/6155/92856/6175/6218/54931/65083/5394/9724/6209/6193/6231/6229/6165/6130/6142/6204/1736/11056/6228/23521/23481/54555/9790/51077/117246/10171/5822/55720/10199/6143/6124/6207/10969/6139/6233/25926/23160/7311/6223/25873/83732/27341/3921/6188/6189/10607/11103/26354/6135/6201/51202/9045/57647/6187/4691/6168/6208/54512/6157/6137/10885/22984/10813/79050/6122/6133/22894/9188/6230 118 Human_respiratory_syncytial_virus_B R-HSA-168273 Influenza Viral RNA Transcription and Replication 90/1832 134/10654 4.797201921539955e-38 3.5186249649367956e-36 1.8000376329649966e-36 6158/23165/6138/6144/6203/5903/9349/6206/6194/6191/55706/7175/6128/51121/6132/9631/6147/6129/6217/5430/6222/6176/6152/6136/6125/6224/6146/348995/6141/6202/79023/57122/23636/6232/10762/5431/6160/23511/6155/6175/6218/53371/5611/6209/6193/23279/4927/6231/6229/9688/6165/79902/6130/2962/6142/6204/9883/6228/5437/23521/23225/3320/6143/6124/6207/8086/6139/6233/7311/6223/25873/9972/3921/6188/6189/8021/6135/6201/129401/9045/6187/55746/6168/6208/6157/6137/8480/6122/6133/6230 90 Human_respiratory_syncytial_virus_B R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 73/1832 94/10654 5.060853469629002e-38 3.5186249649367956e-36 1.8000376329649966e-36 8454/1147/3665/23098/3725/11035/8945/1326/351/4790/6885/5606/7321/8737/10392/8767/1849/29110/5594/6500/330/23118/841/8517/7098/5528/7323/7316/79155/7335/5970/4792/4793/177/3146/7322/5519/64127/5598/1432/329/23291/3656/10454/3661/3654/7189/6285/6233/10010/1385/2353/7311/5518/7187/1386/8772/9641/6197/5599/5600/7334/3551/6416/5608/4791/51231/7314/5595/5515/148022/257397/5516 73 Human_respiratory_syncytial_virus_B R-HSA-3371453 Regulation of HSF1-mediated heat shock response 59/1832 69/10654 1.9943097688222714e-035 1.3172416023071101e-33 6.738667745178411e-34 23165/3303/6118/6782/5903/573/55706/7175/9631/116835/5594/9530/3308/10049/348995/545/79023/472/57122/23636/3337/3313/10808/10762/23511/3305/53371/9532/23279/4927/9688/79902/6119/9883/2932/259217/23225/3310/3309/7266/6767/9531/8086/22824/3306/27000/9972/23411/8021/9529/6117/129401/3304/3312/3297/55746/8480/51182/5595 59 Human_respiratory_syncytial_virus_B R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 71/1832 95/10654 4.378798420973209e-35 2.6292694155025497e-33 1.3450663092176076e-33 8454/23643/1147/3725/8945/1326/351/4790/6885/5606/11213/10392/8767/1849/5594/4214/6500/51295/23118/10333/7099/8517/4615/5528/7316/79155/7335/5970/4792/7096/59307/4793/177/8651/3146/5519/64127/5598/1432/23291/929/114609/3656/10454/695/3654/7189/6285/6233/948/51135/1385/2353/7311/5518/1386/6197/5599/5600/7334/7097/3551/6416/5608/4791/51231/7314/5595/5515/257397/5516 71 Human_respiratory_syncytial_virus_B R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 71/1832 95/10654 4.378798420973209e-35 2.6292694155025497e-33 1.3450663092176076e-33 8454/23643/1147/3725/8945/1326/351/4790/6885/5606/11213/10392/8767/1849/5594/4214/6500/51295/23118/10333/7099/8517/4615/5528/7316/79155/7335/5970/4792/7096/59307/4793/177/8651/3146/5519/64127/5598/1432/23291/929/114609/3656/10454/695/3654/7189/6285/6233/948/51135/1385/2353/7311/5518/1386/6197/5599/5600/7334/7097/3551/6416/5608/4791/51231/7314/5595/5515/257397/5516 71 Human_respiratory_syncytial_virus_B R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 72/1832 98/10654 9.936219665995286e-35 5.469060907824905e-33 2.7978302743723566e-33 8454/23643/1147/3725/8945/1326/351/4790/6885/5606/11213/10392/653509/8767/1849/5594/4214/6500/51295/23118/10333/7099/8517/4615/5528/7316/79155/7335/5970/4792/7096/59307/4793/177/8651/3146/5519/64127/5598/1432/23291/929/114609/3656/10454/695/3654/7189/6285/6233/948/51135/1385/2353/7311/5518/1386/6197/5599/5600/7334/7097/3551/6416/5608/4791/51231/7314/5595/5515/257397/5516 72 Human_respiratory_syncytial_virus_B R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 72/1832 98/10654 9.936219665995286e-35 5.469060907824905e-33 2.7978302743723566e-33 8454/23643/1147/3725/8945/1326/351/4790/6885/5606/11213/10392/653509/8767/1849/5594/4214/6500/51295/23118/10333/7099/8517/4615/5528/7316/79155/7335/5970/4792/7096/59307/4793/177/8651/3146/5519/64127/5598/1432/23291/929/114609/3656/10454/695/3654/7189/6285/6233/948/51135/1385/2353/7311/5518/1386/6197/5599/5600/7334/7097/3551/6416/5608/4791/51231/7314/5595/5515/257397/5516 72 Human_respiratory_syncytial_virus_B R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 68/1832 93/10654 1.2120295059676011e-32 6.15804222070462e-31 3.1502953151060725e-31 54106/8454/23643/1147/3665/3725/8945/1326/351/4790/6885/5606/10392/8767/1849/5594/4214/6500/51295/23118/7099/8517/4615/5528/7316/79155/7335/5970/4792/4793/177/3146/5519/64127/5598/1432/23291/929/3656/10454/3654/7189/6285/6233/51311/51135/1385/2353/7311/5518/1386/6197/5599/353376/5600/7334/3551/6416/5608/4791/51231/51284/7314/5595/5515/148022/257397/5516 68 Human_respiratory_syncytial_virus_B R-HSA-975155 MyD88 dependent cascade initiated on endosome 68/1832 93/10654 1.2120295059676011e-32 6.15804222070462e-31 3.1502953151060725e-31 54106/8454/23643/1147/3665/3725/8945/1326/351/4790/6885/5606/10392/8767/1849/5594/4214/6500/51295/23118/7099/8517/4615/5528/7316/79155/7335/5970/4792/4793/177/3146/5519/64127/5598/1432/23291/929/3656/10454/3654/7189/6285/6233/51311/51135/1385/2353/7311/5518/1386/6197/5599/353376/5600/7334/3551/6416/5608/4791/51231/51284/7314/5595/5515/148022/257397/5516 68 Human_respiratory_syncytial_virus_B R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 67/1832 92/10654 5.309523288868599e-32 2.5977334313316367e-30 1.328933314406877e-30 54106/8454/23643/1147/3725/8945/1326/351/4790/6885/5606/10392/8767/1849/5594/4214/6500/51295/23118/7099/8517/4615/5528/7316/79155/7335/5970/4792/4793/177/3146/5519/64127/5598/1432/23291/929/3656/10454/3654/7189/6285/6233/51311/51135/1385/2353/7311/5518/1386/6197/5599/353376/5600/7334/3551/6416/5608/4791/51231/51284/7314/5595/5515/148022/257397/5516 67 Human_respiratory_syncytial_virus_B R-HSA-1257604 PIP3 activates AKT signaling 127/1832 264/10654 7.542551252158671e-32 3.558467930036288e-30 1.8204202646187473e-30 5295/1147/2308/5170/3725/23396/3643/5684/8841/5290/3667/2309/90865/23035/5291/5468/2065/5525/1822/23186/1459/842/3815/572/23239/2146/5978/5526/10273/207/6045/5594/4303/84335/1027/7249/930/941/2064/57761/6199/4615/5528/2100/7316/10213/1457/4233/1026/55615/4734/6714/2099/1108/64223/81847/10014/5715/5519/8503/1958/2932/2261/5701/5688/3164/10000/3084/2534/23512/57332/5728/6009/5529/5710/6615/3630/3066/3065/7157/1107/23028/942/3654/7189/5371/208/6233/5527/2885/79109/2475/5716/7409/51135/8660/1385/7311/3932/2931/5293/5518/5155/1386/1956/4254/118788/5296/331/4343/117145/8726/648/23466/7874/5781/57521/5696/23608/940/7314/5879/253260/5595/4193/5515/5516 127 Human_respiratory_syncytial_virus_B R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 68/1832 97/10654 8.618752947814833e-31 3.9259905669184116e-29 2.0084353511786286e-29 54106/8454/23643/1147/3665/3725/8945/1326/351/4790/6885/5606/10392/8767/1849/5594/4214/6500/51295/23118/7099/8517/4615/5528/7316/79155/7335/5970/4792/4793/177/3146/5519/64127/5598/1432/23291/929/3656/10454/3654/7189/6285/6233/51311/51135/1385/2353/7311/5518/1386/6197/5599/353376/5600/7334/3551/6416/5608/4791/51231/51284/7314/5595/5515/148022/257397/5516 68 Human_respiratory_syncytial_virus_B R-HSA-5663205 Infectious disease 159/1832 383/10654 2.67180279563571e-30 1.176483831011591e-28 6.018587350168862e-29 60489/6158/23165/3303/5905/6138/8945/1173/6144/3837/6203/5684/5903/9349/8065/7852/6206/6194/6191/55706/7175/6128/5606/51121/6132/9631/1499/1938/3159/6147/6129/6217/5430/6874/6222/6176/6152/6136/7520/8106/6125/4869/821/6500/811/6224/6146/348995/6141/9636/6202/79023/57122/23636/6232/10762/5431/6160/23511/4686/7316/6155/10213/6175/9978/6218/53371/5611/920/292/4233/3055/4836/6209/6193/6714/23279/4927/6231/6229/9688/8148/6165/79902/6130/9150/5715/2962/6142/6204/23327/9883/5701/867/5688/6228/5437/23521/23225/999/9146/3320/2534/6143/5710/6124/6207/8086/5478/3836/6827/6139/6233/2885/3326/6844/2968/5716/7514/163/1025/7311/6223/25873/9972/3932/1213/5610/6880/3921/6188/6189/8021/6135/6201/129401/3304/6829/2547/801/9045/6187/6416/5608/5062/55746/6168/6208/6157/6137/5696/8907/8480/6122/6133/940/7314/5879/6230 159 Human_respiratory_syncytial_virus_B R-HSA-2262752 Cellular responses to stress 182/1832 479/10654 7.813318419144757e-29 3.329481816674266e-27 1.703276884580962e-27 1017/23165/3303/7014/6118/3725/4688/6782/5684/5903/11065/573/4790/55706/7175/5606/9631/9448/3159/246184/112399/1029/7027/1915/526/116835/7321/2146/6045/7422/8697/5594/9530/3308/84335/1027/898/10049/7295/10294/3091/7013/348995/1410/10013/545/79023/472/57122/23636/3337/3576/3313/10808/10762/8881/847/23511/7323/7316/10213/9978/1869/890/10935/3305/53371/6774/5970/1026/9532/54205/832/6667/2289/23279/4927/9688/7415/6647/51433/79902/64223/1031/7322/5715/6119/5598/9883/3552/1432/2932/5701/5688/1387/4683/3281/7846/259217/23225/3310/529/2908/3309/3320/2033/23512/7266/57332/6009/5710/6767/3301/25994/7428/9531/7157/8453/51529/50507/8086/7324/10963/64682/29945/10393/22824/6233/2056/51434/3326/2475/5716/3306/27000/2353/51343/7311/367/9972/2034/79400/57634/10383/23411/8021/9529/4343/8726/6117/6197/29882/5599/648/129401/5600/54583/3304/3312/23466/4217/3456/2113/6416/1536/5608/54386/3569/3297/57521/55746/55466/5696/2288/8480/10919/10728/7314/996/51182/5595/4193 182 Human_respiratory_syncytial_virus_B R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 59/1832 80/10654 8.189165288956923e-29 3.3805897958475296e-27 1.7294224064178765e-27 23165/3837/5903/5335/55706/7175/9631/2316/4600/348995/9636/79023/57122/23636/11274/8638/25820/7706/10762/23511/7316/53371/4734/3434/6772/23279/4927/9688/79902/23586/6041/9883/4939/6059/23225/1981/3661/8086/7324/3836/9246/51191/4599/6233/3716/7311/9972/7318/5610/5300/8021/4940/129401/7334/4938/55746/8480/7314/5595 59 Human_respiratory_syncytial_virus_B R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 61/1832 85/10654 1.185126714607477e-28 4.473006828561363e-27 2.2882747391819557e-27 8454/1147/3725/8945/1326/351/81793/4790/6885/5606/10392/8767/1849/5594/4214/6500/51295/23118/8517/4615/7100/5528/7316/79155/7335/5970/4792/4793/177/3146/5519/64127/5598/1432/23291/3656/10454/3654/7189/6285/6233/51135/1385/2353/7311/5518/1386/6197/5599/5600/7334/3551/6416/5608/4791/51231/7314/5595/5515/257397/5516 61 Human_respiratory_syncytial_virus_B R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 61/1832 85/10654 1.185126714607477e-28 4.473006828561363e-27 2.2882747391819557e-27 8454/1147/3725/8945/1326/351/81793/4790/6885/5606/10392/8767/1849/5594/4214/6500/51295/23118/8517/4615/7100/5528/7316/79155/7335/5970/4792/4793/177/3146/5519/64127/5598/1432/23291/3656/10454/3654/7189/6285/6233/51135/1385/2353/7311/5518/1386/6197/5599/5600/7334/3551/6416/5608/4791/51231/7314/5595/5515/257397/5516 61 Human_respiratory_syncytial_virus_B R-HSA-975871 MyD88 cascade initiated on plasma membrane 61/1832 85/10654 1.185126714607477e-28 4.473006828561363e-27 2.2882747391819557e-27 8454/1147/3725/8945/1326/351/81793/4790/6885/5606/10392/8767/1849/5594/4214/6500/51295/23118/8517/4615/7100/5528/7316/79155/7335/5970/4792/4793/177/3146/5519/64127/5598/1432/23291/3656/10454/3654/7189/6285/6233/51135/1385/2353/7311/5518/1386/6197/5599/5600/7334/3551/6416/5608/4791/51231/7314/5595/5515/257397/5516 61 Human_respiratory_syncytial_virus_B R-HSA-156902 Peptide chain elongation 62/1832 89/10654 6.226370084538288e-28 2.2847319115764106e-26 1.168809822887012e-26 6158/6138/6144/6203/9349/6206/6194/6191/6128/51121/6132/1938/6147/6129/1915/6217/6222/6176/6152/6136/6125/6224/6146/6141/6202/6232/6160/6155/6175/6218/6209/6193/6231/6229/6165/6130/6142/6204/6228/23521/6143/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/9045/6187/6168/6208/6157/6137/6122/6133/6230 62 Human_respiratory_syncytial_virus_B R-HSA-8953897 Cellular responses to external stimuli 183/1832 493/10654 1.5527417576798735e-27 5.543707734851656e-26 2.8360176626756155e-26 1017/23165/3303/7014/6118/3725/4688/6782/5684/5903/11065/573/4790/55706/7175/5606/9631/9448/3159/246184/112399/1029/7027/1915/526/116835/7321/2146/6045/7422/8697/5594/9530/3308/84335/1027/898/10049/7295/10294/3091/7013/348995/1410/10013/545/79023/472/57122/23636/3337/3576/3313/10808/10762/8881/847/23511/7323/7316/10213/9978/1869/890/10935/3305/53371/6774/5970/1026/9532/54205/832/6667/2289/23279/4927/9688/7415/6647/51433/79902/64223/1031/7322/5715/6119/5598/9883/3552/1432/2932/5701/5688/1387/4683/3281/7846/259217/23225/3310/529/2908/3309/3320/2033/23512/7266/57332/6009/5710/6767/3301/25994/7428/9531/7157/8453/51529/50507/8086/7324/10963/64682/29945/10393/22824/6233/2056/51434/3326/2475/5716/3306/27000/2353/51343/7311/367/9972/2034/79400/57634/10383/23411/8021/9529/4343/8726/6117/4520/6197/29882/5599/648/129401/5600/54583/3304/3312/23466/4217/3456/2113/6416/1536/5608/54386/3569/3297/57521/55746/55466/5696/2288/8480/10919/10728/7314/996/51182/5595/4193 183 Human_respiratory_syncytial_virus_B R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 64/1832 95/10654 1.7434900096541134e-27 6.06092184935022e-26 3.100611042099559e-26 6158/6138/6144/6203/9349/6206/6194/6191/6128/51121/6132/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/6141/26986/6202/6232/6160/4686/6155/6175/6218/6209/6193/6231/6229/6165/6130/6142/6204/6228/23521/1981/6143/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/9045/5976/6187/6168/6208/6157/6137/6122/6133/6230 64 Human_respiratory_syncytial_virus_B R-HSA-9006925 Intracellular signaling by second messengers 132/1832 305/10654 2.3595294180685778e-27 7.992149644278439e-26 4.0885772912281427e-26 5295/1147/2308/5170/3725/23396/3643/5684/8841/5290/3667/5335/2309/90865/23035/5291/5468/2065/5525/1822/23186/1459/842/3815/572/23239/2146/5978/5526/10273/207/6045/5578/5594/4303/84335/1027/7249/5582/930/941/2064/57761/6199/4615/5528/2100/7316/10213/1457/4233/1026/55615/4734/6714/2099/1108/64223/81847/10014/5715/5519/8503/1958/2932/2261/5701/5688/3164/10000/3084/2534/23512/57332/5728/6009/5529/5710/6615/3630/3066/3065/7157/1107/23028/942/3654/7189/5371/208/6233/5527/2885/79109/5580/2475/5716/7409/51135/8660/1385/7311/3932/2931/5293/5518/5155/1386/1956/4254/118788/5296/331/4343/117145/8726/648/23466/7874/801/5781/57521/5696/23608/940/7314/5879/253260/5595/4193/5515/5516 132 Human_respiratory_syncytial_virus_B R-HSA-5663202 Diseases of signal transduction 152/1832 377/10654 2.4337412870486966e-27 8.03743060047832e-26 4.111741858645429e-26 5295/8454/4000/1147/2308/5170/5684/4893/8841/5290/3667/5335/71/142678/2309/5291/1499/2065/10018/5525/892/55869/842/55750/3815/572/5430/5526/8844/207/1452/5594/3280/9530/4303/84335/613/1027/7249/6500/409/930/941/10533/10013/23385/2064/6199/5431/6776/5528/2100/4686/7316/10213/673/9978/9611/6774/4233/1026/55615/57085/6772/6714/2099/6934/4609/5664/7415/64223/10014/5715/2962/5519/8850/8503/2932/2261/5701/867/5688/1387/5437/7046/3717/4088/2244/3164/10000/3320/3084/2335/2534/2033/3690/408/55294/5728/5529/1445/5710/3066/3065/4296/5894/4087/942/208/6233/5527/2885/79109/2475/5716/2266/7409/56829/8660/1385/7311/5906/3932/2931/5293/5518/5155/2243/1956/11160/60/4254/118788/5296/3845/6777/3265/369/801/5781/5696/7750/11140/5245/940/7314/5879/253260/5595/4193/5515/5516 152 Human_respiratory_syncytial_virus_B R-HSA-192823 Viral mRNA Translation 61/1832 89/10654 6.881839043816823e-27 2.217294969971225e-25 1.1343108257074199e-25 6158/6138/6144/6203/9349/6206/6194/6191/6128/51121/6132/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/6141/6202/6232/6160/6155/6175/6218/5611/6209/6193/6231/6229/6165/6130/6142/6204/6228/23521/6143/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/9045/6187/6168/6208/6157/6137/6122/6133/6230 61 Human_respiratory_syncytial_virus_B R-HSA-156842 Eukaryotic Translation Elongation 62/1832 93/10654 2.813559520465824e-26 8.849314586988937e-25 4.527080732178093e-25 6158/6138/6144/6203/9349/6206/6194/6191/6128/51121/6132/1938/6147/6129/1915/6217/6222/6176/6152/6136/6125/6224/6146/6141/6202/6232/6160/6155/6175/6218/6209/6193/6231/6229/6165/6130/6142/6204/6228/23521/6143/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/9045/6187/6168/6208/6157/6137/6122/6133/6230 62 Human_respiratory_syncytial_virus_B R-HSA-72689 Formation of a pool of free 40S subunits 65/1832 101/10654 3.680440259404174e-26 1.130665484342538e-24 5.784192525183548e-25 6158/6138/6144/6203/9349/6206/6194/6191/6128/51121/6132/6147/8666/6129/6217/6222/6176/6152/6136/6125/6224/6146/6141/6202/6232/6160/6155/8661/6175/6218/6209/6193/6231/6229/6165/6130/6142/6204/8663/6228/23521/6143/6124/6207/6139/6233/7311/6223/25873/8664/51386/3921/6188/6189/6135/6201/9045/6187/6168/6208/6157/6137/6122/6133/6230 65 Human_respiratory_syncytial_virus_B R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 45/1832 55/10654 1.2064286404404944e-25 3.6220278045952116e-24 1.852935854456453e-24 1147/834/9447/596/351/4790/6885/842/10392/8767/10910/58484/7295/330/23118/29108/841/8517/7316/7335/5970/64127/7128/1432/329/598/3656/5603/10454/83737/3654/7189/6233/3326/7311/114548/5600/7334/1540/3551/6300/5608/4791/7314/257397 45 Human_respiratory_syncytial_virus_B R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 68/1832 111/10654 1.867348720339353e-25 5.481705910151745e-24 2.8042991308955896e-24 6158/6138/6144/6203/9349/6206/6194/6191/6128/51121/6132/6147/8666/6129/6217/6222/6176/6152/6136/6125/6224/6146/6141/26986/6202/6232/6160/6155/8661/6175/6218/6209/6193/6231/6229/6165/6130/6142/6204/8663/6228/23521/8894/1981/6143/6124/6207/6139/6233/7311/6223/25873/8664/51386/3921/6188/6189/6135/6201/9045/6187/6168/6208/6157/6137/6122/6133/6230 68 Human_respiratory_syncytial_virus_B R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 68/1832 112/10654 3.97112679171913e-25 1.1404040199697761e-23 5.834012357628561e-24 6158/6138/6144/6203/9349/6206/6194/6191/6128/51121/6132/6147/8666/6129/6217/6222/6176/6152/6136/6125/6224/6146/6141/6202/6232/6160/6155/8661/6175/6218/9669/6209/6193/6231/6229/6165/6130/6142/6204/8663/6228/23521/8894/1981/6143/6124/6207/6139/6233/7311/6223/25873/8664/51386/3921/6188/6189/6135/6201/9045/6187/6168/6208/6157/6137/6122/6133/6230 68 Human_respiratory_syncytial_virus_B R-HSA-1169408 ISG15 antiviral mechanism 52/1832 72/10654 8.105530031820716e-25 2.2781713131989714e-23 1.1654535902416348e-23 23165/3837/5903/5335/55706/7175/9631/4600/348995/9636/79023/57122/23636/11274/25820/7706/10762/23511/7316/53371/4734/3434/6772/23279/4927/9688/79902/23586/9883/23225/1981/3661/8086/7324/3836/9246/51191/4599/6233/3716/7311/9972/7318/5610/5300/8021/129401/7334/55746/8480/7314/5595 52 Human_respiratory_syncytial_virus_B R-HSA-72613 Eukaryotic Translation Initiation 70/1832 119/10654 1.1509535084454309e-24 3.102876703380437e-23 1.587351562668027e-23 6158/6138/6144/6203/9349/6206/6194/6191/6128/51121/6132/6147/8666/6129/6217/6222/6176/6152/6136/6125/6224/6146/6141/26986/6202/6232/6160/6155/8661/6175/6218/9669/6209/6193/6231/6229/6165/6130/6142/6204/8663/6228/23521/8894/1981/6143/6124/6207/6139/6233/7311/6223/25873/8664/51386/3921/6188/6189/6135/6201/1978/9045/6187/6168/6208/6157/6137/6122/6133/6230 70 Human_respiratory_syncytial_virus_B R-HSA-72737 Cap-dependent Translation Initiation 70/1832 119/10654 1.1509535084454309e-24 3.102876703380437e-23 1.587351562668027e-23 6158/6138/6144/6203/9349/6206/6194/6191/6128/51121/6132/6147/8666/6129/6217/6222/6176/6152/6136/6125/6224/6146/6141/26986/6202/6232/6160/6155/8661/6175/6218/9669/6209/6193/6231/6229/6165/6130/6142/6204/8663/6228/23521/8894/1981/6143/6124/6207/6139/6233/7311/6223/25873/8664/51386/3921/6188/6189/6135/6201/1978/9045/6187/6168/6208/6157/6137/6122/6133/6230 70 Human_respiratory_syncytial_virus_B R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 33/1832 34/10654 1.3113831552807373e-24 3.464674296251708e-23 1.7724378646110175e-23 7321/9140/29110/57506/9636/54476/7706/84166/7323/9474/7316/3093/23586/7322/7128/64135/54941/83737/3661/9246/51191/6233/7311/55593/84282/7318/79671/5094/7187/5300/9641/1540/7314 33 Human_respiratory_syncytial_virus_B R-HSA-2408557 Selenocysteine synthesis 60/1832 93/10654 2.5087332623878555e-24 6.373147383873764e-23 3.2603375596214643e-23 6158/6138/6144/6203/9349/6206/6194/6191/6128/51121/6132/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/6141/6202/6232/6160/6155/6175/6218/6209/6193/6231/6229/6165/6130/6142/6204/6228/23521/6143/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/9045/6187/6168/6208/6157/6137/6122/6133/6230 60 Human_respiratory_syncytial_virus_B R-HSA-72764 Eukaryotic Translation Termination 60/1832 93/10654 2.5087332623878555e-24 6.373147383873764e-23 3.2603375596214643e-23 6158/6138/6144/6203/9349/6206/6194/6191/6128/51121/6132/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/6141/6202/6232/6160/6155/6175/6218/6209/6193/6231/6229/6165/6130/6142/6204/6228/23521/6143/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/9045/6187/6168/6208/6157/6137/6122/6133/6230 60 Human_respiratory_syncytial_virus_B R-HSA-927802 Nonsense-Mediated Decay (NMD) 67/1832 115/10654 2.4978791000886607e-23 6.1105523911428155e-22 3.1260007451401945e-22 6158/6138/6144/6203/9349/6206/6194/6191/6128/51121/6132/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/6141/26986/6202/6232/6160/4686/6155/6175/6218/6209/6193/6231/6229/6165/6130/6142/6204/6228/23521/1981/6143/6124/6207/6139/6233/7311/6223/25873/5518/3921/6188/6189/23049/6135/6201/9045/5976/6187/6168/6208/6157/6137/6122/6133/5515/6230 67 Human_respiratory_syncytial_virus_B R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 67/1832 115/10654 2.4978791000886607e-23 6.1105523911428155e-22 3.1260007451401945e-22 6158/6138/6144/6203/9349/6206/6194/6191/6128/51121/6132/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/6141/26986/6202/6232/6160/4686/6155/6175/6218/6209/6193/6231/6229/6165/6130/6142/6204/6228/23521/1981/6143/6124/6207/6139/6233/7311/6223/25873/5518/3921/6188/6189/23049/6135/6201/9045/5976/6187/6168/6208/6157/6137/6122/6133/5515/6230 67 Human_respiratory_syncytial_virus_B R-HSA-450294 MAP kinase activation 47/1832 64/10654 4.5745022068363107e-23 1.0987122573146848e-21 5.6207280704094e-22 8454/1147/3725/8945/1326/4790/6885/5606/10392/8767/1849/5594/6500/23118/8517/5528/7316/79155/7335/5519/64127/5598/1432/23291/3656/10454/3654/7189/6233/1385/2353/7311/5518/1386/6197/5599/5600/7334/3551/6416/5608/51231/7314/5595/5515/257397/5516 47 Human_respiratory_syncytial_virus_B R-HSA-6790901 rRNA modification in the nucleus and cytosol 46/1832 62/10654 6.446809504064557e-23 1.5207563133695141e-21 7.779796431596701e-22 9136/2091/6203/55127/55813/8602/6194/25879/10436/9277/84128/56902/10528/84135/27340/57050/88745/51602/51096/134430/55272/92856/65083/9724/1736/11056/54555/9790/51077/10171/5822/10199/25926/23160/27341/10607/11103/6201/51202/57647/6187/6208/10885/22984/10813/79050 46 Human_respiratory_syncytial_virus_B R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 64/1832 108/10654 6.672426950319115e-23 1.546364210766939e-21 7.9107998192149065e-22 5295/3605/7124/2308/596/9655/3592/3566/2309/3561/7412/7184/3593/207/5292/3684/9021/7422/3553/4582/5743/3091/4318/3383/6778/3576/3662/3597/3565/4985/6774/1026/3718/7133/3606/6772/8651/4609/149233/3552/3717/598/3320/4843/2335/7157/948/3716/2353/6347/3687/51561/3570/7431/5008/3312/3929/7297/3569/3162/4170/3689/3586/3596 64 Human_respiratory_syncytial_virus_B R-HSA-388841 Costimulation by the CD28 family 49/1832 70/10654 1.760878531078987e-22 4.010552654405761e-21 2.05169513058568e-21 5295/5170/5777/1326/5290/5525/5526/207/5133/941/57761/5528/3122/9020/920/55615/3113/6714/64223/5519/8503/29126/4067/10000/2534/5529/1445/916/998/942/208/5527/2885/7525/79109/2475/7409/3932/5518/5296/117145/5781/5062/1493/940/5879/253260/5515/5516 49 Human_respiratory_syncytial_virus_B R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 39/1832 48/10654 3.5953068862073975e-22 8.049831180813513e-21 4.118085675192059e-21 5295/5777/3635/5290/1437/5291/3561/1439/1438/6776/7316/3560/3055/6850/3718/8503/867/3558/4067/3717/29760/3636/2534/3563/6233/2885/7525/1398/7006/3716/7409/7311/5293/5296/6777/1399/3559/5781/7314 39 Human_respiratory_syncytial_virus_B R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 165/1832 473/10654 1.5510804853145343e-21 3.414962201834166e-20 1.7470064413542648e-20 5295/54106/5170/5777/1173/4688/3643/5590/4893/8065/857/5290/2670/3667/85440/5335/71/558/5579/5770/5291/1499/2065/5747/4690/526/3815/5430/10273/207/10019/1849/7422/5578/5594/10193/2322/1785/3315/3178/9101/10817/23118/51741/23385/4318/2064/57761/5921/6778/348/5431/6776/5528/9306/4686/7316/673/5753/9611/5140/9047/6774/11059/4233/55615/4734/10413/6772/6714/2099/8651/5664/26052/64223/2962/5519/8503/5598/1432/2261/867/5437/4067/3717/4914/529/10000/9146/3320/3084/2335/2534/3690/4846/3728/8471/5771/1445/5603/3630/998/83737/3914/7072/6285/208/6233/2885/7525/1398/79109/7410/7006/5580/2475/7409/8660/23191/1385/3685/163/7311/5906/3932/3479/1759/5518/5155/2185/1213/387/1956/60/4254/5296/581/117145/6197/3845/5600/6777/3265/1399/6300/801/1020/5781/1536/5062/3480/11033/5725/11140/53916/51231/1291/7314/5879/253260/5595/5515/6387/5516/2242 165 Human_respiratory_syncytial_virus_B R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 63/1832 112/10654 6.761298031473543e-21 1.4642089671436967e-19 7.490514816576385e-20 6158/6138/6144/6203/9349/6206/6194/6191/6128/51121/6132/6147/6129/6217/6222/6176/6152/6136/6125/6727/6224/6146/6141/6202/6232/6160/6155/6748/6175/6218/6209/6193/6231/6229/6165/6130/6142/6204/6228/23521/6143/6124/6207/6139/6745/6233/7311/6223/25873/3921/6188/6189/6135/6201/9045/6187/6168/6208/6157/6137/6122/6133/6230 63 Human_respiratory_syncytial_virus_B R-HSA-168638 NOD1/2 Signaling Pathway 32/1832 36/10654 7.825921868385978e-21 1.6674262561512704e-19 8.53012196859728e-20 1147/834/6885/842/10392/8767/330/23118/841/8517/7316/7335/64127/7128/1432/329/3656/5603/10454/83737/3654/7189/6233/7311/5600/7334/1540/3551/6300/5608/7314/257397 32 Human_respiratory_syncytial_virus_B R-HSA-5688426 Deubiquitination 118/1832 297/10654 8.913640152150708e-21 1.8690347049192198e-19 9.561498709575195e-20 9960/23032/5684/8295/7186/645836/6885/90865/7419/7321/991/8737/10392/8767/4738/7375/55611/9817/57506/4303/100287364/51720/91833/409/6478/1080/330/3091/9101/100287513/11274/4287/27005/7706/8517/86/64750/580/7416/29086/7316/10213/993/79155/890/7417/4792/9986/983/8678/2099/4609/7415/392188/23586/81847/5715/100287144/100287441/64127/8850/7128/3416/5701/5688/9097/329/7046/6502/7347/4088/9146/2033/408/64135/5728/5710/10454/8473/100287327/7157/10869/9929/9958/4087/63891/7189/57599/6233/377630/5716/672/100287478/9804/7311/55593/84282/367/114548/7187/387/60/23770/728386/8607/7345/3054/1540/29761/7874/100287404/100287178/5696/100287205/7314/4193/100287238/7528 118 Human_respiratory_syncytial_virus_B R-HSA-9009391 Extra-nuclear estrogen signaling 50/1832 77/10654 1.143156289561027e-20 2.359546028922057e-19 1.2070827925956896e-19 5295/2788/5170/596/5590/4893/857/5290/54331/2309/5747/59345/207/5594/1027/3315/10681/51764/94235/4318/2100/55970/2792/6714/2099/8503/2793/10000/3320/2785/4846/2783/2784/2782/2786/208/7514/1385/2353/1956/5296/3845/3276/3265/801/3480/2791/5595/2790/2787 50 Human_respiratory_syncytial_virus_B R-HSA-448424 Interleukin-17 signaling 48/1832 72/10654 1.2580114129499158e-20 2.5566662715489825e-19 1.3079244163786977e-19 8454/3605/1147/3725/8945/1326/4790/6885/5606/10392/8767/1849/5594/6500/23118/8517/5528/7316/79155/7335/5519/64127/5598/1432/23291/3656/10454/3654/7189/6233/1385/2353/7311/5518/1386/6197/5599/5600/7334/3551/6416/5608/51231/7314/5595/5515/257397/5516 48 Human_respiratory_syncytial_virus_B R-HSA-389356 CD28 co-stimulation 30/1832 33/10654 3.018213490729238e-20 6.041000032202005e-19 3.090419555100751e-19 5295/5170/1326/5290/207/941/57761/9020/55615/6714/64223/8503/4067/10000/2534/998/942/208/2885/7525/79109/2475/7409/3932/5296/117145/5062/940/5879/253260 30 Human_respiratory_syncytial_virus_B R-HSA-392451 G beta:gamma signalling through PI3Kgamma 25/1832 25/10654 6.700706623604512e-20 1.3017108014384647e-18 6.659216180114701e-19 2788/5170/54331/59345/207/10681/51764/94235/55970/2792/146850/2793/23533/10000/5294/2785/2783/2784/2782/2786/208/387/2791/2790/2787 25 Human_respiratory_syncytial_virus_B R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 25/1832 25/10654 6.700706623604512e-20 1.3017108014384647e-18 6.659216180114701e-19 1147/2308/5170/2309/842/572/207/4303/84335/1027/7249/6199/1026/55615/64223/2932/3164/10000/208/79109/2475/1385/2931/253260/4193 25 Human_respiratory_syncytial_virus_B R-HSA-4420097 VEGFA-VEGFR2 Pathway 57/1832 99/10654 1.0794939441611762e-19 2.0666833336766865e-18 1.0572618034347444e-18 5295/5170/4688/5590/4893/857/5290/5335/71/558/5579/5291/1499/5747/4690/207/7422/5578/3315/57761/5921/9047/55615/6714/64223/1432/10000/3320/2534/3690/4846/3728/5603/998/208/1398/79109/7410/5580/2475/7409/23191/3685/2185/387/60/5296/117145/3845/5600/3265/6300/801/1536/5062/5879/253260 57 Human_respiratory_syncytial_virus_B R-HSA-6804757 Regulation of TP53 Degradation 31/1832 36/10654 2.470293042951827e-19 4.6617958710562336e-18 2.384854336203117e-18 1017/5170/1029/6446/207/11200/472/7316/890/80196/983/55615/64223/5519/1616/10000/7157/208/6233/5527/79109/2475/7311/5518/7874/51230/7314/253260/4193/5515/5516 31 Human_respiratory_syncytial_virus_B R-HSA-5260271 Diseases of Immune System 24/1832 24/10654 3.939630055802868e-19 7.228126810716095e-18 3.697722947113218e-18 23643/1147/81793/4790/10333/7099/8517/4615/7098/7100/5970/4792/7096/929/114609/695/948/51135/81622/7187/7097/3551/4791/148022 24 Human_respiratory_syncytial_virus_B R-HSA-5602358 Diseases associated with the TLR signaling cascade 24/1832 24/10654 3.939630055802868e-19 7.228126810716095e-18 3.697722947113218e-18 23643/1147/81793/4790/10333/7099/8517/4615/7098/7100/5970/4792/7096/929/114609/695/948/51135/81622/7187/7097/3551/4791/148022 24 Human_respiratory_syncytial_virus_B R-HSA-2219528 PI3K/AKT Signaling in Cancer 57/1832 101/10654 4.0199371609706785e-19 7.274434232386666e-18 3.7214126277479094e-18 5295/1147/2308/5170/5290/3667/2309/5291/2065/842/3815/572/207/4303/84335/1027/7249/930/941/2064/6199/2100/4233/1026/55615/6714/2099/64223/8503/2932/2261/3164/10000/3084/2534/5728/942/208/2885/79109/2475/7409/8660/1385/3932/2931/5293/5155/1956/4254/118788/5296/5781/940/5879/253260/4193 57 Human_respiratory_syncytial_virus_B R-HSA-933541 TRAF6 mediated IRF7 activation 27/1832 29/10654 5.495773507560018e-19 9.810698383090248e-18 5.01889984616434e-18 3443/3665/3441/7186/80143/29110/57506/3449/7706/3444/23586/1387/3451/3448/2033/64135/3440/3661/7189/3439/10010/84282/3452/9641/3456/3446/3445 27 Human_respiratory_syncytial_virus_B R-HSA-6806003 Regulation of TP53 Expression and Degradation 31/1832 37/10654 1.2732857070792875e-18 2.2426805587356516e-17 1.1472974371156527e-17 1017/5170/1029/6446/207/11200/472/7316/890/80196/983/55615/64223/5519/1616/10000/7157/208/6233/5527/79109/2475/7311/5518/7874/51230/7314/253260/4193/5515/5516 31 Human_respiratory_syncytial_virus_B R-HSA-3232142 SUMOylation of ubiquitinylation proteins 31/1832 38/10654 5.7776066551134185e-18 1.0042392620269508e-16 5.137428632386169e-17 23165/5903/55706/7175/9631/51588/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/7428/8086/7329/5371/9972/9063/8021/129401/55746/8480/4193/8554 31 Human_respiratory_syncytial_virus_B R-HSA-446652 Interleukin-1 family signaling 68/1832 140/10654 7.63416773161719e-18 1.3097059186319882e-16 6.70011713424229e-17 8454/1147/834/5777/8945/1326/5684/351/4790/6885/90865/4215/11213/10392/8767/29110/3553/8878/54472/6500/23118/25930/8517/4615/7316/3565/10213/9978/79155/6774/7335/5970/4792/59307/4793/3606/177/3146/5715/64127/3552/5701/5688/23291/4088/3656/5771/5710/10454/3654/7189/6285/6233/5716/51135/7311/5599/7334/3551/6416/5781/5608/5696/4791/3554/7314/3596/257397 68 Human_respiratory_syncytial_virus_B R-HSA-2408522 Selenoamino acid metabolism 61/1832 118/10654 7.947020262019765e-18 1.345899200785655e-16 6.885272615677042e-17 6158/6138/6144/6203/9349/6206/6194/6191/6128/51121/6132/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/6141/6202/6232/6160/6155/6175/6218/6209/6193/6231/6229/6165/6130/6142/6204/6228/23521/7965/6143/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/9045/6187/6168/6208/6157/6137/6122/6133/6230 61 Human_respiratory_syncytial_virus_B R-HSA-389357 CD28 dependent PI3K/Akt signaling 22/1832 22/10654 1.3599639193055366e-17 2.274066249876726e-16 1.1633535458949424e-16 5295/5170/1326/5290/207/941/57761/9020/55615/64223/8503/10000/2534/942/208/79109/2475/3932/5296/117145/940/253260 22 Human_respiratory_syncytial_virus_B R-HSA-199418 Negative regulation of the PI3K/AKT network 58/1832 110/10654 1.5282643088447678e-17 2.523546439979923e-16 1.2909811661557117e-16 5295/23396/3643/5290/3667/90865/23035/5291/2065/5525/3815/23239/5526/207/5594/930/941/2064/57761/4615/5528/2100/4233/6714/2099/5519/8503/2261/10000/3084/2534/5728/5529/3630/942/3654/7189/208/5527/2885/7409/51135/8660/3932/5293/5518/5155/1956/4254/118788/5296/117145/5781/940/5879/5595/5515/5516 58 Human_respiratory_syncytial_virus_B R-HSA-194138 Signaling by VEGF 57/1832 107/10654 1.5519074694345807e-17 2.5309503297815815e-16 1.294768804908383e-16 5295/5170/4688/5590/4893/857/5290/5335/71/558/5579/5291/1499/5747/4690/207/7422/5578/3315/57761/5921/9047/55615/6714/64223/1432/10000/3320/2534/3690/4846/3728/5603/998/208/1398/79109/7410/5580/2475/7409/23191/3685/2185/387/60/5296/117145/3845/5600/3265/6300/801/1536/5062/5879/253260 57 Human_respiratory_syncytial_virus_B R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 28/1832 33/10654 3.1889762672370957e-17 5.137362986610004e-16 2.6281421868629204e-16 1147/351/4790/6885/10392/8767/23118/8517/7316/7335/5970/4792/4793/177/3146/64127/3656/10454/3654/7189/6285/6233/7311/7334/3551/4791/7314/257397 28 Human_respiratory_syncytial_virus_B R-HSA-9010553 Regulation of expression of SLITs and ROBOs 76/1832 171/10654 5.291662356607675e-17 8.422031292865951e-16 4.30849363721259e-16 6158/6138/6144/23032/6203/5684/9349/6206/6194/6191/6128/51121/6132/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/6141/26986/6202/6232/6160/4686/7316/6155/10213/6175/9978/6218/6209/6193/6231/6229/6165/6130/5715/6142/6204/5701/5688/6228/23521/1981/6143/5710/6124/8453/6207/6139/6233/5716/7311/6223/25873/3921/6188/6189/6135/6201/9045/6187/6168/6208/6157/6137/5696/6122/6133/7314/6230 76 Human_respiratory_syncytial_virus_B R-HSA-389513 CTLA4 inhibitory signaling 21/1832 21/10654 7.984813006060569e-17 1.2535451916886941e-15 6.412813363593303e-16 5525/5526/207/941/5528/6714/5519/4067/10000/2534/5529/942/208/5527/7525/3932/5518/5781/1493/5515/5516 21 Human_respiratory_syncytial_virus_B R-HSA-376176 Signaling by ROBO receptors 89/1832 218/10654 8.065960733803104e-17 1.2535451916886941e-15 6.412813363593303e-16 6158/6138/6144/25/23032/6203/5684/9349/7852/6206/6194/6191/6128/51121/6132/2817/6147/6129/4690/6217/6222/6176/6152/6136/5578/6125/6224/6146/6141/26986/6202/6232/6160/4686/7316/6155/10213/6175/9978/6218/5216/6209/6193/6714/6231/6229/6165/6130/5715/6142/6204/5701/5688/6228/23521/1981/6143/9495/5710/6124/998/8453/6207/6139/6233/5716/7311/6223/25873/387/3921/6188/6189/6135/6201/9045/6187/5062/6168/6208/6157/6137/5696/6122/6133/7314/5879/6387/6230 89 Human_respiratory_syncytial_virus_B R-HSA-912694 Regulation of IFNA signaling 24/1832 26/10654 8.964306024799491e-17 1.3769590998558287e-15 7.044167035399355e-16 3443/5777/3441/5770/3455/9021/11274/3449/3444/6772/8651/3451/3448/3440/3454/3439/3716/3452/3456/6773/7297/5781/3446/3445 24 Human_respiratory_syncytial_virus_B R-HSA-3700989 Transcriptional Regulation by TP53 127/1832 365/10654 1.1458022522539868e-16 1.739775603709789e-15 8.900242540194307e-16 9377/1017/23774/834/6118/2176/5170/3725/64769/7862/1029/7027/1459/6446/5430/6874/7532/207/10971/9212/7832/1027/58484/4869/7249/898/355/7295/7533/55367/4292/11200/545/472/580/5431/7316/1869/890/80196/84289/1457/983/1026/54205/55615/6790/6341/1108/8148/64223/9150/2962/9656/5519/6119/1432/1387/4683/27154/5437/1616/51499/843/10000/51755/2033/995/5728/6009/7994/54541/3066/3065/7157/1107/55215/6827/5371/208/10498/6233/5527/79109/2968/2475/672/1025/2353/7311/7161/51204/5562/5518/6834/1386/6880/10419/5300/581/5983/4343/6117/1340/1327/5600/7159/4697/3276/6829/5564/7874/51230/317/1020/2744/5608/10397/57521/7248/10919/7314/253260/4193/5515/1263/5516 127 Human_respiratory_syncytial_virus_B R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 26/1832 30/10654 1.5278904271755005e-16 2.2935718798850412e-15 1.1733321223046306e-15 11065/7319/7321/65264/7320/10477/92912/7326/7316/7317/54926/55236/3093/7322/7347/7328/7324/6233/7327/7311/55284/27338/7874/7332/997/7314 26 Human_respiratory_syncytial_virus_B R-HSA-397795 G-protein beta:gamma signalling 27/1832 32/10654 1.5943757866706124e-16 2.3664836114515493e-15 1.210631880594362e-15 2788/5170/54331/59345/207/10681/51764/94235/55970/2792/146850/2793/23533/10000/5294/2785/2783/2784/2782/998/695/2786/208/387/2791/2790/2787 27 Human_respiratory_syncytial_virus_B R-HSA-1433557 Signaling by SCF-KIT 32/1832 43/10654 2.1770660359359825e-16 3.195449148301592e-15 1.6347092340010534e-15 5295/5777/4893/5290/3815/10019/5578/4318/6776/9306/6774/6772/6714/8651/8503/867/4067/3717/2534/2885/7525/7006/7409/3932/4254/5296/3845/6777/3265/5781/5879/2242 32 Human_respiratory_syncytial_virus_B R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 78/1832 182/10654 2.5974518124768707e-16 3.7705866420680724e-15 1.9289347178833437e-15 23165/23468/7150/5905/5893/5903/7068/55706/7175/9631/5468/1029/1786/6045/9212/51588/4869/348995/51602/79023/57122/23636/8517/3183/10762/23511/53371/54780/5970/4792/3190/6790/6672/2099/23279/4927/9688/79902/9656/9883/1387/10401/1616/23225/2908/2033/23512/165918/8243/9126/57332/142/7067/7428/3066/3065/7157/1107/8086/7329/5371/8924/672/7158/367/9972/9063/8021/9641/6117/648/129401/11315/55746/4791/8480/4193/8554 78 Human_respiratory_syncytial_virus_B R-HSA-9020702 Interleukin-1 signaling 54/1832 103/10654 2.7874754510708175e-16 4.002451163983206e-15 2.047550617376962e-15 8454/1147/8945/1326/5684/351/4790/6885/4215/11213/10392/8767/3553/8878/54472/6500/23118/8517/4615/7316/10213/9978/79155/7335/5970/4792/4793/177/3146/5715/64127/3552/5701/5688/23291/3656/5710/10454/3654/7189/6285/6233/5716/51135/7311/7334/3551/6416/5608/5696/4791/3554/7314/257397 54 Human_respiratory_syncytial_virus_B R-HSA-937041 IKK complex recruitment mediated by RIP1 23/1832 25/10654 4.865291876320219e-16 6.910807063031193e-15 3.5353903617403285e-15 23643/1147/23098/11035/7321/8737/330/7099/8517/7323/7316/7335/7322/329/929/7189/6233/7311/353376/7334/3551/7314/148022 23 Human_respiratory_syncytial_virus_B R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 27/1832 33/10654 7.334027506431763e-16 1.0306649293613147e-14 5.272615519741535e-15 23165/3303/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/7514/9972/8021/129401/3304/55746/8480 27 Human_respiratory_syncytial_virus_B R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 26/1832 31/10654 7.92396263958833e-16 1.1018478575680194e-14 5.636768991263942e-15 23165/3837/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/3836/9972/8021/129401/55746/8480 26 Human_respiratory_syncytial_virus_B R-HSA-6783783 Interleukin-10 signaling 33/1832 47/10654 1.2778648040409918e-15 1.7583952147272396e-14 8.995495660025402e-15 729230/7124/3592/1437/3587/3593/3553/1230/2919/5743/941/3383/3576/2357/2920/6352/6774/1435/6348/1440/3627/7133/3606/6364/3552/942/3716/6347/3588/7297/3569/3586/3554 33 Human_respiratory_syncytial_virus_B R-HSA-912631 Regulation of signaling by CBL 21/1832 22/10654 1.4710664382791734e-15 2.0033801700688535e-14 1.0248775402878235e-14 5295/5290/5291/7316/3055/6850/8503/867/4067/29760/2534/6233/2885/7525/1398/7409/7311/5293/5296/1399/7314 21 Human_respiratory_syncytial_virus_B R-HSA-2990846 SUMOylation 78/1832 188/10654 2.331532606605819e-15 3.1428107891084554e-14 1.607780809281349e-14 23165/23468/7150/5905/5893/5903/7068/55706/7175/9631/5468/1029/1786/6045/9212/51588/4869/348995/51602/79023/57122/23636/8517/3183/10762/23511/53371/54780/5970/4792/3190/6790/6672/2099/23279/4927/9688/79902/9656/9883/1387/10401/1616/23225/2908/2033/23512/165918/8243/9126/57332/142/7067/7428/3066/3065/7157/1107/8086/7329/5371/8924/672/7158/367/9972/9063/8021/9641/6117/648/129401/11315/55746/4791/8480/4193/8554 78 Human_respiratory_syncytial_virus_B R-HSA-177243 Interactions of Rev with host cellular proteins 28/1832 36/10654 2.3776016298470544e-15 3.172537124270666e-14 1.6229880344091534e-14 23165/5905/3837/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/7514/9972/8021/129401/55746/8480 28 Human_respiratory_syncytial_virus_B R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 44/1832 77/10654 2.452164097352531e-15 3.2393087726026936e-14 1.6571466847371842e-14 23165/5893/5903/55706/7175/9631/1029/6045/51588/348995/79023/57122/23636/10762/23511/53371/54780/6672/23279/4927/9688/79902/9656/9883/23225/165918/8243/9126/57332/142/8086/7329/5371/8924/672/9972/9063/8021/6117/648/129401/55746/8480/8554 44 Human_respiratory_syncytial_virus_B R-HSA-5633007 Regulation of TP53 Activity 70/1832 160/10654 2.496484909058207e-15 3.2652045196692e-14 1.670394279953485e-14 1017/23774/6118/5170/64769/7862/1029/1459/6446/6874/207/9212/11200/545/472/580/7316/890/80196/84289/1457/983/55615/6790/1108/8148/64223/5519/6119/1432/4683/27154/1616/10000/2033/7994/3066/3065/7157/1107/5371/208/6233/5527/79109/2475/672/7311/7161/5562/5518/6880/10419/5300/5983/6117/5600/7159/5564/7874/51230/1020/5608/10919/7314/253260/4193/5515/1263/5516 70 Human_respiratory_syncytial_virus_B R-HSA-159227 Transport of the SLBP independent Mature mRNA 27/1832 34/10654 2.9793916883631375e-15 3.8586043336546126e-14 1.973962295076506e-14 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/9972/8021/129401/55746/8480 27 Human_respiratory_syncytial_virus_B R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 62/1832 134/10654 4.058359742805568e-15 5.204944874025393e-14 2.6627153345745265e-14 5295/8454/1147/5170/3725/8945/5684/4893/5290/5335/4790/6885/5291/7321/5336/5594/4214/6500/23118/8517/7316/10213/7335/5970/4792/6850/8915/7322/5715/5701/5688/4067/23291/2534/5710/10454/695/7189/6233/2885/7410/7006/5716/7409/3702/2353/7311/5296/3845/5599/7334/3265/3551/801/6416/5062/5696/997/7314/5879/5595/257397 62 Human_respiratory_syncytial_virus_B R-HSA-5689880 Ub-specific processing proteases 86/1832 220/10654 5.841187538328686e-15 7.419431478973264e-14 3.795589473286454e-14 9960/23032/5684/8295/7186/645836/6885/90865/7419/991/8737/7375/55611/9817/4303/100287364/91833/409/6478/1080/330/3091/9101/100287513/11274/27005/8517/64750/7416/7316/10213/993/890/7417/4792/9986/8678/4609/392188/23586/81847/5715/100287144/100287441/3416/5701/5688/9097/329/7046/6502/4088/9146/408/64135/5728/5710/10454/100287327/7157/10869/9958/4087/63891/7189/57599/6233/377630/5716/100287478/9804/7311/367/23770/728386/8607/1540/29761/7874/100287404/100287178/5696/100287205/7314/4193/100287238 86 Human_respiratory_syncytial_virus_B R-HSA-162909 Host Interactions of HIV factors 60/1832 129/10654 8.384231307466516e-15 1.0548161483012637e-13 5.3961669166852166e-14 60489/23165/5905/8945/1173/3837/5684/5903/8065/55706/7175/9631/3159/4869/6500/348995/79023/57122/23636/10762/23511/7316/10213/9978/53371/920/292/3055/23279/4927/9688/79902/5715/9883/5701/5688/23225/2534/5710/8086/5478/3836/6233/5716/7514/163/1025/7311/9972/3932/8021/129401/5062/55746/5696/8907/8480/940/7314/5879 60 Human_respiratory_syncytial_virus_B R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 27/1832 35/10654 1.090247719358973e-14 1.3586955068615126e-13 6.950735211801992e-14 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/9972/8021/129401/55746/8480 27 Human_respiratory_syncytial_virus_B R-HSA-180746 Nuclear import of Rev protein 26/1832 33/10654 1.3941956741520184e-14 1.7053078569952e-13 8.723914452296256e-14 23165/3837/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 26 Human_respiratory_syncytial_virus_B R-HSA-180910 Vpr-mediated nuclear import of PICs 26/1832 33/10654 1.3941956741520184e-14 1.7053078569952e-13 8.723914452296256e-14 23165/5903/55706/7175/9631/3159/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/3836/9972/8021/129401/55746/8480 26 Human_respiratory_syncytial_virus_B R-HSA-8964315 G beta:gamma signalling through BTK 18/1832 18/10654 1.6116990454569492e-14 1.9532609532556238e-13 9.992378437309138e-14 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/695/2786/2791/2790/2787 18 Human_respiratory_syncytial_virus_B R-HSA-877300 Interferon gamma signaling 48/1832 92/10654 1.6285316879232716e-14 1.9557185088605836e-13 1.0004950656906606e-13 3135/3665/3460/5777/6737/10379/960/5770/7412/3107/2633/9021/85363/9830/3383/8638/7706/2634/3662/3122/3394/3663/3664/6672/3113/6772/8651/3659/3106/3459/4939/3717/5771/3458/3661/5371/5580/3716/81603/3133/3134/4940/4938/5781/4261/3105/3660/8554 48 Human_respiratory_syncytial_virus_B R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 25/1832 31/10654 1.6916904930276536e-14 2.013264091251829e-13 1.0299338990267932e-13 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/7514/9972/8021/129401/55746/8480 25 Human_respiratory_syncytial_virus_B R-HSA-168276 NS1 Mediated Effects on Host Pathways 29/1832 40/10654 1.8006452687418506e-14 2.123796785721415e-13 1.0864795700491241e-13 23165/3837/5903/55706/7175/9631/8106/348995/9636/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/3836/9972/5610/8021/129401/55746/8480 29 Human_respiratory_syncytial_virus_B R-HSA-4615885 SUMOylation of DNA replication proteins 31/1832 45/10654 2.1792394129094685e-14 2.547588729604786e-13 1.3032805804265288e-13 23165/7150/5905/5903/55706/7175/9631/9212/51588/348995/79023/57122/23636/10762/23511/53371/6790/23279/4927/9688/79902/9883/10401/23225/8086/7329/9972/8021/129401/55746/8480 31 Human_respiratory_syncytial_virus_B R-HSA-5621481 C-type lectin receptors (CLRs) 63/1832 142/10654 2.8310023169465905e-14 3.2804860181460056e-13 1.6782118997965937e-13 8454/1147/5170/8945/5684/4893/4790/6885/7321/5336/3553/9039/4582/6500/3384/23118/29108/841/8517/7316/10213/64581/9020/7335/5970/4792/6850/8915/6714/7322/5715/93978/170482/5701/5688/1387/4067/23291/2534/2033/3385/5710/10454/9040/5894/7189/6233/5580/30835/5716/7311/3845/7334/3265/3551/801/5062/5696/997/26253/4791/7314/257397 63 Human_respiratory_syncytial_virus_B R-HSA-176033 Interactions of Vpr with host cellular proteins 27/1832 36/10654 3.6477103884817823e-014 4.1901090636386387e-13 2.1435515509430702e-13 23165/5903/55706/7175/9631/3159/348995/79023/57122/23636/10762/23511/53371/292/23279/4927/9688/79902/9883/23225/8086/3836/9972/8021/129401/55746/8480 27 Human_respiratory_syncytial_virus_B R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 51/1832 103/10654 3.847875356234977e-14 4.3819339186089696e-13 2.241684191200413e-13 5295/23396/3643/5290/3667/90865/5291/2065/5525/3815/5526/207/5594/930/941/2064/4615/5528/2100/4233/6714/2099/5519/8503/2261/3084/2534/5529/3630/942/3654/7189/5527/2885/7409/51135/8660/3932/5293/5518/5155/1956/4254/118788/5296/5781/940/5879/5595/5515/5516 51 Human_respiratory_syncytial_virus_B R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 19/1832 20/10654 4.607255066434895e-14 5.201866617744015e-13 2.661140578183718e-13 1147/11035/7321/8737/330/8517/7098/7323/7316/7335/7322/329/7189/6233/7311/7334/3551/7314/148022 19 Human_respiratory_syncytial_virus_B R-HSA-165054 Rev-mediated nuclear export of HIV RNA 26/1832 34/10654 4.9570293164280525e-14 5.502719098320552e-13 2.8150489351143827e-13 23165/5905/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/7514/9972/8021/129401/55746/8480 26 Human_respiratory_syncytial_virus_B R-HSA-4085377 SUMOylation of SUMOylation proteins 26/1832 34/10654 4.9570293164280525e-14 5.502719098320552e-13 2.8150489351143827e-13 23165/5903/55706/7175/9631/51588/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/7329/9972/8021/129401/55746/8480 26 Human_respiratory_syncytial_virus_B R-HSA-9607240 FLT3 Signaling 96/1832 267/10654 7.209887042180562e-14 7.936883985600436e-13 4.0603048079648426e-13 5295/54106/5170/5684/2674/4893/5290/1437/3667/71/5291/2065/3561/5525/5747/3815/5526/8844/1849/7010/1439/5594/2322/409/10817/2064/57761/5921/1438/8452/6776/5528/7316/10213/673/9978/3560/5140/4233/3055/84078/3718/6714/5715/5519/2261/5701/5688/3558/3717/2244/3084/2335/2534/3690/408/5529/1445/5710/4296/5894/3563/208/6233/5527/2885/6709/3716/5716/2266/8660/7311/5906/5518/5155/2243/1956/60/4254/5536/5296/1843/117145/3845/6777/3265/3559/369/801/5781/5696/5245/7314/5595/5515/5516 96 Human_respiratory_syncytial_virus_B R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 24/1832 30/10654 8.032401508686334e-14 8.769258176012105e-13 4.4861259404755336e-13 7124/1147/81858/7186/6885/8737/55072/7375/330/23118/27005/8517/7316/7128/329/10616/10454/6233/7311/331/1540/3551/7314/257397 24 Human_respiratory_syncytial_virus_B R-HSA-450302 activated TAK1 mediates p38 MAPK activation 21/1832 24/10654 9.492694008037568e-14 1.027856457755543e-12 5.258248104538496e-13 6885/5606/10392/8767/23118/8517/7316/7335/64127/1432/3656/10454/3654/7189/6233/7311/5600/7334/5608/7314/257397 21 Human_respiratory_syncytial_virus_B R-HSA-5357801 Programmed Cell Death 73/1832 181/10654 1.0566536797725539e-13 1.1348288707150763e-12 5.805491334308769e-13 23643/4000/2934/11035/3837/596/5684/7186/2339/1499/4976/10018/5747/1029/7027/842/572/8737/7532/207/10971/5594/10059/355/330/7533/841/7099/7316/10213/1869/6774/54205/5339/4836/115209/3146/5715/5701/5688/329/999/598/836/929/10000/4137/5710/3002/7157/3836/208/6233/5580/6709/5716/7311/7161/8772/331/581/5599/353376/7159/7431/26060/317/8743/5062/5696/7314/5595/148022 73 Human_respiratory_syncytial_virus_B R-HSA-4570464 SUMOylation of RNA binding proteins 31/1832 47/10654 1.3721566709732453e-13 1.4617894857706912e-12 7.478137374913612e-13 23165/5903/55706/7175/9631/6045/348995/51602/79023/57122/23636/3183/10762/23511/53371/3190/23279/4927/9688/79902/9883/23225/57332/8086/7329/9972/8021/648/129401/55746/8480 31 Human_respiratory_syncytial_virus_B R-HSA-168253 Host Interactions with Influenza Factors 29/1832 42/10654 1.3899198945649435e-13 1.4688673445762323e-12 7.514345872090053e-13 23165/3837/5903/55706/7175/9631/8106/348995/9636/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/3836/9972/5610/8021/129401/55746/8480 29 Human_respiratory_syncytial_virus_B R-HSA-5683057 MAPK family signaling cascades 102/1832 294/10654 1.6207525232000444e-13 1.6992175263073481e-12 8.692757893854874e-13 2308/3725/5684/2674/4893/1437/3667/71/2309/2065/3561/5525/5747/10642/3815/5526/8844/1849/7010/1439/5594/2322/3315/409/10817/2064/5921/3337/1438/5596/8452/5528/7316/10213/673/9978/3560/4233/983/5597/84078/3718/6714/4609/5715/5519/2261/5701/5688/3558/3717/2244/3084/2335/2534/3690/408/5529/1445/5710/4296/998/5894/3563/6233/5527/2885/6709/3716/5716/2266/8660/7514/7311/5906/5518/5155/2243/1956/60/4254/5536/1843/4343/3570/3845/3265/3559/369/801/7297/5781/3569/5062/5696/5245/7314/3572/5879/5595/5515/5516 102 Human_respiratory_syncytial_virus_B R-HSA-392851 Prostacyclin signalling through prostacyclin receptor 18/1832 19/10654 2.567444459099879e-13 2.670546559425937e-12 1.3661826297075194e-12 2788/54331/59345/10681/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 18 Human_respiratory_syncytial_virus_B R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 24/1832 31/10654 2.977198213380185e-13 3.0487432867249803e-12 1.5596583051734627e-12 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 24 Human_respiratory_syncytial_virus_B R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 24/1832 31/10654 2.977198213380185e-13 3.0487432867249803e-12 1.5596583051734627e-12 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 24 Human_respiratory_syncytial_virus_B R-HSA-5689896 Ovarian tumor domain proteases 27/1832 38/10654 3.262357249125279e-13 3.3150568662265335e-12 1.695897452581724e-12 7321/8737/10392/8767/55611/57506/7706/8517/7316/79155/983/2099/7415/23586/64127/7128/64135/5728/7157/7189/6233/7311/55593/84282/7187/387/7314 27 Human_respiratory_syncytial_virus_B R-HSA-75893 TNF signaling 29/1832 43/10654 3.5700757290179117e-13 3.6000534641470694e-12 1.8416943495616707e-12 7124/1147/25999/81858/7186/6885/8737/55072/7375/9530/330/23118/841/27005/8517/7316/7128/329/10616/10454/8567/6233/7311/8772/331/1540/3551/7314/257397 29 Human_respiratory_syncytial_virus_B R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 35/1832 59/10654 3.846075979585942e-13 3.848989673509871e-12 1.969043683328688e-12 6203/6206/6194/6191/8666/6217/6222/6224/26986/6202/6232/8661/6218/6209/6193/6231/6229/6204/8663/6228/8894/1981/6207/6233/6223/8664/51386/3921/6188/6189/6201/1978/6187/6208/6230 35 Human_respiratory_syncytial_virus_B R-HSA-390466 Chaperonin-mediated protein folding 47/1832 95/10654 4.0237583463816644e-13 3.9965299064437435e-12 2.044521454987755e-12 2788/10694/26224/8841/54331/2629/59345/1459/10575/10528/10681/5203/898/51764/94235/10517/7203/10576/908/55970/6774/1457/2792/26272/2793/26270/6950/7846/2785/55294/2783/26190/2784/2782/7157/2786/10574/6468/10383/60/54461/22948/26234/2791/84261/2790/2787 47 Human_respiratory_syncytial_virus_B R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 32/1832 51/10654 4.3729433013574114e-13 4.310938881412791e-12 2.2053649642352378e-12 6203/6206/6194/6191/8666/6217/6222/6224/6202/6232/8661/6218/6209/6193/6231/6229/6204/8663/6228/8894/6207/6233/6223/8664/51386/3921/6188/6189/6201/6187/6208/6230 32 Human_respiratory_syncytial_virus_B R-HSA-109581 Apoptosis 71/1832 178/10654 4.410827656614381e-13 4.316076543990813e-12 2.2079932596853274e-12 23643/4000/2934/3837/596/5684/7186/2339/1499/4976/10018/5747/1029/7027/842/572/8737/7532/207/10971/5594/10059/355/7533/841/7099/7316/10213/1869/6774/54205/5339/4836/115209/3146/5715/5701/5688/329/999/598/836/929/10000/4137/5710/3002/7157/3836/208/6233/5580/6709/5716/7311/7161/8772/331/581/5599/353376/7159/7431/26060/317/8743/5062/5696/7314/5595/148022 71 Human_respiratory_syncytial_virus_B R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 20/1832 23/10654 4.879816648343957e-13 4.739880729751741e-12 2.424800532691038e-12 11065/246184/7321/991/8697/8881/7316/983/51433/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 20 Human_respiratory_syncytial_virus_B R-HSA-9006335 Signaling by Erythropoietin 21/1832 25/10654 4.969298533001043e-13 4.791564497879108e-12 2.4512406132821125e-12 5295/4893/5290/5335/5291/5336/6776/4067/23533/3717/5294/2057/2885/2056/7409/8660/5293/3845/6777/3265/1399 21 Human_respiratory_syncytial_virus_B R-HSA-451927 Interleukin-2 family signaling 29/1832 44/10654 8.757905599680789e-13 8.383473403752407e-12 4.288768417234985e-12 5295/5777/3635/5290/1437/5291/3561/6775/1439/1438/6776/3560/6774/6850/3718/6772/8503/3558/3717/3636/3563/2885/3716/3932/5293/2185/5296/6777/3559 29 Human_respiratory_syncytial_virus_B R-HSA-72649 Translation initiation complex formation 34/1832 58/10654 1.3506093670571501e-12 1.2835647294118672e-11 6.566385563428174e-12 6203/6206/6194/6191/8666/6217/6222/6224/26986/6202/6232/8661/6218/6209/6193/6231/6229/6204/8663/6228/8894/1981/6207/6233/6223/8664/51386/3921/6188/6189/6201/6187/6208/6230 34 Human_respiratory_syncytial_virus_B R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 17/1832 18/10654 1.4262071371343652e-12 1.3457283058246403e-11 6.88439836120498e-12 23643/3665/23098/29110/7099/7316/929/3661/6233/10010/7311/7187/9641/353376/5781/7314/148022 17 Human_respiratory_syncytial_virus_B R-HSA-1227986 Signaling by ERBB2 31/1832 50/10654 1.622209690680558e-12 1.5198148946021396e-11 7.774980376386102e-12 5295/4893/8065/5290/5335/2065/10273/207/5578/10193/9101/2064/7316/5753/6714/10000/3320/3084/2534/208/6233/2885/7525/5580/7311/387/1956/3845/3265/11140/7314 31 Human_respiratory_syncytial_virus_B R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 25/1832 35/10654 2.068116833504764e-12 1.9239312232815444e-11 9.84233511571578e-12 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/983/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 25 Human_respiratory_syncytial_virus_B R-HSA-8964616 G beta:gamma signalling through CDC42 18/1832 20/10654 2.152791503120722e-12 1.9886976053304014e-11 1.0173663194725826e-11 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/998/2786/2791/2790/2787 18 Human_respiratory_syncytial_virus_B R-HSA-933542 TRAF6 mediated NF-kB activation 20/1832 24/10654 2.4532552886044995e-12 2.235000162928651e-11 1.143368345033821e-11 1147/351/7186/4790/57506/4214/7706/8517/5970/4792/4793/177/3146/23586/64135/7189/6285/84282/3551/4791 20 Human_respiratory_syncytial_virus_B R-HSA-982772 Growth hormone receptor signaling 20/1832 24/10654 2.4532552886044995e-12 2.235000162928651e-11 1.143368345033821e-11 5777/3667/5770/2690/9021/5594/6776/6774/6772/8651/4067/3717/5618/2688/8660/1154/8835/6777/2689/5595 20 Human_respiratory_syncytial_virus_B R-HSA-187037 Signaling by NTRK1 (TRKA) 41/1832 80/10654 2.9077827703205637e-12 2.6309459175297704e-11 1.3459239643444859e-11 5295/1173/4893/5290/3667/5335/5291/1849/5594/1785/5528/673/6774/6714/26052/5519/5598/1432/4914/5603/2885/1398/8660/1385/163/5906/1759/5518/1213/387/5296/6197/3845/5600/3265/1399/6300/51231/5595/5515/5516 41 Human_respiratory_syncytial_virus_B R-HSA-76002 Platelet activation, signaling and aggregation 91/1832 262/10654 3.1775897432096407e-12 2.855507517537371e-11 1.4608038776516928e-11 5295/2788/5170/5777/5590/351/5290/54331/5579/5770/5291/5747/59345/51097/5336/2316/207/813/3959/7422/5578/5594/5582/10681/409/51764/94235/10447/335/51706/55970/5216/6850/2792/6714/6647/1191/8503/4352/146850/1432/3920/27154/2793/4067/23533/2244/81/3309/9948/2335/5294/2534/3690/408/2785/2783/2784/1445/2782/998/5894/5478/2786/2885/1398/7410/948/5580/2266/7409/8407/5906/3932/3479/5155/2243/387/5296/29789/10916/213/801/5781/2791/5879/5595/2790/2787/139322/3700 91 Human_respiratory_syncytial_virus_B R-HSA-168325 Viral Messenger RNA Synthesis 28/1832 43/10654 3.408452293389804e-12 3.0422739726810344e-11 1.556348771234889e-11 23165/5903/55706/7175/9631/5430/348995/79023/57122/23636/10762/5431/23511/53371/23279/4927/9688/79902/2962/9883/5437/23225/8086/9972/8021/129401/55746/8480 28 Human_respiratory_syncytial_virus_B R-HSA-8939211 ESR-mediated signaling 81/1832 223/10654 3.6421700045718705e-12 3.2290648161338527e-11 1.6519061412470086e-11 5295/2788/5170/3725/596/5590/4893/857/5290/54331/2309/5747/59345/5430/207/5594/1027/3315/10681/51764/94235/4318/5481/200845/5431/2100/865/55970/6667/2792/2289/6714/2099/4609/2962/8850/8503/1387/5437/2793/10000/3320/2033/8243/2785/4846/9126/2783/4602/2784/2782/3065/861/23028/2786/208/10498/3326/7514/1385/1025/2353/23030/1386/1956/5536/5296/4343/3845/3276/3265/801/3480/2791/2288/10728/5595/2790/2787/7528/6387 81 Human_respiratory_syncytial_virus_B R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 35/1832 63/10654 5.460792436478201e-12 4.809137872391803e-11 2.4602306976975474e-11 1147/3665/170506/11035/6737/4790/1499/8737/29110/7520/8517/6778/4615/7098/5591/7316/51428/5970/4792/4793/3428/1387/5437/2033/22954/1660/3661/6233/7311/3551/2547/4791/7314/9533/148022 35 Human_respiratory_syncytial_virus_B R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 27/1832 41/10654 5.593587867244428e-12 4.8934632931323774e-11 2.5033694045109257e-11 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/9972/8021/129401/55746/8480 27 Human_respiratory_syncytial_virus_B R-HSA-166520 Signaling by NTRKs 47/1832 101/10654 6.708731859859638e-12 5.754697913554924e-11 2.943954787443532e-11 5295/1173/4893/5290/3667/5335/5291/1849/5594/1785/10817/5528/673/6774/6714/26052/5519/5598/1432/4914/2534/5603/2885/1398/8660/1385/163/5906/1759/5518/1213/387/5296/581/6197/3845/5600/3265/1399/6300/1020/5781/51231/5879/5595/5515/5516 47 Human_respiratory_syncytial_virus_B R-HSA-391251 Protein folding 47/1832 101/10654 6.708731859859638e-12 5.754697913554924e-11 2.943954787443532e-11 2788/10694/26224/8841/54331/2629/59345/1459/10575/10528/10681/5203/898/51764/94235/10517/7203/10576/908/55970/6774/1457/2792/26272/2793/26270/6950/7846/2785/55294/2783/26190/2784/2782/7157/2786/10574/6468/10383/60/54461/22948/26234/2791/84261/2790/2787 47 Human_respiratory_syncytial_virus_B R-HSA-5607764 CLEC7A (Dectin-1) signaling 47/1832 101/10654 6.708731859859638e-12 5.754697913554924e-11 2.943954787443532e-11 8454/1147/5170/8945/5684/4790/6885/7321/5336/3553/9039/6500/23118/29108/841/8517/7316/10213/64581/9020/7335/5970/4792/6850/8915/6714/7322/5715/5701/5688/23291/5710/10454/9040/7189/6233/5580/5716/7311/7334/3551/801/5696/997/4791/7314/257397 47 Human_respiratory_syncytial_virus_B R-HSA-2980766 Nuclear Envelope Breakdown 31/1832 52/10654 7.161562481048224e-12 6.103499379009488e-11 3.122392606338173e-11 4000/23165/5903/55706/7175/5579/9631/5578/348995/79023/57122/23636/7443/10762/23511/53371/983/23279/4927/9688/79902/9883/23225/8086/9972/5347/8021/129401/55746/7112/8480 31 Human_respiratory_syncytial_virus_B R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 16/1832 17/10654 7.895030195310474e-12 6.685471082054574e-11 3.420114295134497e-11 23643/23098/6885/23118/7099/7316/929/3656/10454/7189/6233/7311/353376/7314/148022/257397 16 Human_respiratory_syncytial_virus_B R-HSA-912526 Interleukin receptor SHC signaling 21/1832 27/10654 8.159183745290962e-12 6.865147597152458e-11 3.512032158549646e-11 5295/5777/3635/5290/1437/5291/3561/1439/1438/3560/3718/8503/3558/3717/3636/3563/2885/3716/5293/5296/3559 21 Human_respiratory_syncytial_virus_B R-HSA-72702 Ribosomal scanning and start codon recognition 33/1832 58/10654 9.088589608136009e-12 7.598751185030169e-11 3.887324802413936e-11 6203/6206/6194/6191/8666/6217/6222/6224/6202/6232/8661/6218/6209/6193/6231/6229/6204/8663/6228/8894/1981/6207/6233/6223/8664/51386/3921/6188/6189/6201/6187/6208/6230 33 Human_respiratory_syncytial_virus_B R-HSA-202403 TCR signaling 52/1832 119/10654 1.0395914151988107e-11 8.637108550173767e-11 4.418521605810238e-11 5295/8454/1147/5170/8945/5684/3635/5290/5335/4790/6885/5291/4690/7321/8767/6500/23118/5788/8517/7316/10213/3122/920/7335/5970/4792/8915/3113/7322/5715/5701/5688/23291/5728/1445/5710/916/7189/7535/6233/5716/3702/26191/7311/3932/5296/7334/3551/5062/5696/997/7314 52 Human_respiratory_syncytial_virus_B R-HSA-5684996 MAPK1/MAPK3 signaling 88/1832 255/10654 1.0875830299999442e-11 8.979357391437038e-11 4.593607271447133e-11 5684/2674/4893/1437/3667/71/2065/3561/5525/5747/3815/5526/8844/1849/7010/1439/5594/2322/409/10817/2064/5921/1438/8452/5528/7316/10213/673/9978/3560/4233/983/84078/3718/6714/5715/5519/2261/5701/5688/3558/3717/2244/3084/2335/2534/3690/408/5529/1445/5710/4296/5894/3563/6233/5527/2885/6709/3716/5716/2266/8660/7311/5906/5518/5155/2243/1956/60/4254/5536/1843/3570/3845/3265/3559/369/801/7297/5781/3569/5696/5245/7314/3572/5595/5515/5516 88 Human_respiratory_syncytial_virus_B R-HSA-5686938 Regulation of TLR by endogenous ligand 17/1832 19/10654 1.1366640012541518e-11 9.326292830166054e-11 4.771090479275354e-11 23643/653509/6271/6280/10333/7099/338/7096/6279/3146/2244/929/948/2266/2243/7097/3929 17 Human_respiratory_syncytial_virus_B R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 19/1832 23/10654 1.2011877911000855e-11 9.794870815081561e-11 5.010802871255716e-11 6885/10392/8767/23118/8517/7316/7335/64127/3656/10454/3654/7189/6233/7311/5599/7334/6416/7314/257397 19 Human_respiratory_syncytial_virus_B R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 27/1832 42/10654 1.3103408967917429e-11 1.0554636125987148e-10 5.399479176767002e-11 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/9972/8021/129401/55746/8480 27 Human_respiratory_syncytial_virus_B R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 27/1832 42/10654 1.3103408967917429e-11 1.0554636125987148e-10 5.399479176767002e-11 2788/10694/54331/59345/1459/10575/10681/51764/94235/7203/10576/908/55970/1457/2792/2793/6950/2785/2783/2784/2782/2786/10574/22948/2791/2790/2787 27 Human_respiratory_syncytial_virus_B R-HSA-198323 AKT phosphorylates targets in the cytosol 14/1832 14/10654 1.8961131537081475e-11 1.4998595664960854e-10 7.672894072994835e-11 1147/842/572/207/84335/1027/7249/1026/2932/10000/208/2931/23608/4193 14 Human_respiratory_syncytial_virus_B R-HSA-3371568 Attenuation phase 14/1832 14/10654 1.8961131537081475e-11 1.4998595664960854e-10 7.672894072994835e-11 3303/3337/3305/1387/3281/3320/2033/3326/3306/3304/3312/3297/2288/10728 14 Human_respiratory_syncytial_virus_B R-HSA-918233 TRAF3-dependent IRF activation pathway 14/1832 14/10654 1.8961131537081475e-11 1.4998595664960854e-10 7.672894072994835e-11 3665/80143/29110/57506/7706/23586/1387/2033/64135/3661/84282/7187/9641/3456 14 Human_respiratory_syncytial_virus_B R-HSA-5357905 Regulation of TNFR1 signaling 23/1832 33/10654 3.6215855103092434e-11 2.8476871780467323e-10 1.4568031939965755e-10 7124/1147/25999/81858/7186/8737/55072/7375/330/841/27005/8517/7316/7128/329/10616/8567/6233/7311/331/1540/3551/7314 23 Human_respiratory_syncytial_virus_B R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 15/1832 16/10654 4.3536907041990936e-11 3.383073776615884e-10 1.730693146808556e-10 8454/1147/8945/1326/4790/6500/8517/7316/79155/23291/6233/7311/3551/6416/7314 15 Human_respiratory_syncytial_virus_B R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 15/1832 16/10654 4.3536907041990936e-11 3.383073776615884e-10 1.730693146808556e-10 23643/6885/23118/7099/7316/929/3656/10454/7189/6233/7311/353376/7314/148022/257397 15 Human_respiratory_syncytial_virus_B R-HSA-3371571 HSF1-dependent transactivation 19/1832 24/10654 4.833464387610767e-11 3.7339219041133466e-10 1.9101779851314944e-10 3303/84335/1410/3337/3305/64223/1387/3281/3320/2033/3326/2475/3306/3304/3312/3297/57521/2288/10728 19 Human_respiratory_syncytial_virus_B R-HSA-418217 G beta:gamma signalling through PLC beta 17/1832 20/10654 6.357844823259296e-11 4.882972681119494e-10 2.4980026784164426e-10 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Human_respiratory_syncytial_virus_B R-HSA-186763 Downstream signal transduction 21/1832 29/10654 8.303613287558042e-11 6.304065030381708e-10 3.224996812227624e-10 5295/4893/5290/5335/5291/4690/5921/6778/6776/6774/6772/6714/2885/1398/5155/5296/3845/6777/3265/1399/5781 21 Human_respiratory_syncytial_virus_B R-HSA-5218920 VEGFR2 mediated vascular permeability 21/1832 29/10654 8.303613287558042e-11 6.304065030381708e-10 3.224996812227624e-10 5170/857/1499/207/57761/55615/64223/10000/3320/4846/3728/208/79109/7410/2475/7409/117145/801/5062/5879/253260 21 Human_respiratory_syncytial_virus_B R-HSA-191859 snRNP Assembly 30/1832 53/10654 9.618345222408464e-11 7.219223885682717e-10 3.6931684406616223e-10 23165/6635/5903/6633/6632/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/79084/8086/9972/10419/8021/129401/55746/8480 30 Human_respiratory_syncytial_virus_B R-HSA-194441 Metabolism of non-coding RNA 30/1832 53/10654 9.618345222408464e-11 7.219223885682717e-10 3.6931684406616223e-10 23165/6635/5903/6633/6632/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/79084/8086/9972/10419/8021/129401/55746/8480 30 Human_respiratory_syncytial_virus_B R-HSA-202424 Downstream TCR signaling 44/1832 98/10654 1.3720051214543778e-10 1.0239654042040864e-9 5.238342479772289e-10 5295/8454/1147/5170/8945/5684/3635/5290/4790/6885/5291/7321/8767/6500/23118/8517/7316/10213/3122/920/7335/5970/4792/8915/3113/7322/5715/5701/5688/23291/5728/5710/916/7189/6233/5716/7311/3932/5296/7334/3551/5696/997/7314 44 Human_respiratory_syncytial_virus_B R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 22/1832 32/10654 1.4872327747283402e-10 1.1037272446158076e-9 5.646383449885242e-10 2788/54331/59345/5594/10681/409/51764/94235/55970/2792/6714/2793/408/2785/2783/2784/2782/2786/2791/5595/2790/2787 22 Human_respiratory_syncytial_virus_B R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 19/1832 25/10654 1.68845585556011e-10 1.2391389917749474e-9 6.339114966488834e-10 11065/246184/7321/991/8697/8881/7316/51433/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 19 Human_respiratory_syncytial_virus_B R-HSA-418592 ADP signalling through P2Y purinoceptor 1 19/1832 25/10654 1.68845585556011e-10 1.2391389917749474e-9 6.339114966488834e-10 2788/54331/59345/10681/51764/94235/55970/2792/6714/1432/2793/2785/2783/2784/2782/2786/2791/2790/2787 19 Human_respiratory_syncytial_virus_B R-HSA-5675221 Negative regulation of MAPK pathway 25/1832 40/10654 1.861236436310512e-10 1.358394106279661e-9 6.949193324288157e-10 4893/5525/5526/8844/1849/5594/5528/7316/673/5519/5529/5894/6233/5527/7311/5518/5536/1843/3845/3265/369/7314/5595/5515/5516 25 Human_respiratory_syncytial_virus_B R-HSA-2559583 Cellular Senescence 70/1832 195/10654 1.9833749082438171e-10 1.439581458126419e-9 7.36452684264043e-10 1017/7014/3725/11065/4790/5606/9448/3159/246184/1029/7027/7321/2146/6045/8697/5594/1027/898/7295/7013/472/3576/8881/7316/1869/890/6774/5970/1026/6667/51433/1031/5598/3552/1432/4683/23512/57332/7157/51529/7324/64682/29945/10393/6233/51434/2353/51343/7311/57634/4343/8726/6197/29882/5599/648/5600/23466/4217/3456/2113/6416/5608/54386/3569/10919/7314/996/5595/4193 70 Human_respiratory_syncytial_virus_B R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 14/1832 15/10654 2.390599505109407e-10 1.7256731946718727e-9 8.828098258730166e-10 54106/3665/4615/7316/7335/3654/7189/6233/51311/51135/7311/7334/51284/7314 14 Human_respiratory_syncytial_virus_B R-HSA-500657 Presynaptic function of Kainate receptors 17/1832 21/10654 2.8008020518793963e-10 2.010793212246023e-9 1.0286698611593663e-9 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Human_respiratory_syncytial_virus_B R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 16/1832 19/10654 3.171334794510026e-10 2.252329711584809e-9 1.1522336944399754e-9 11065/246184/7321/991/8697/8881/51433/51529/7324/64682/29945/10393/51434/51343/29882/996 16 Human_respiratory_syncytial_virus_B R-HSA-176412 Phosphorylation of the APC/C 16/1832 19/10654 3.171334794510026e-10 2.252329711584809e-9 1.1522336944399754e-9 11065/246184/7321/8697/8881/983/51433/51529/7324/64682/29945/10393/51434/5347/29882/996 16 Human_respiratory_syncytial_virus_B R-HSA-6807070 PTEN Regulation 55/1832 140/10654 3.822161234239427e-10 2.700040101834376e-9 1.381270764076393e-9 3725/5684/8841/5468/1822/23186/1459/2146/5978/10273/207/6045/5594/7316/10213/1457/4734/1108/64223/81847/10014/5715/1958/5701/5688/10000/23512/57332/5728/6009/5710/6615/3066/3065/7157/1107/23028/5371/208/6233/2475/5716/7311/1386/331/4343/8726/648/23466/7874/57521/5696/23608/7314/5595 55 Human_respiratory_syncytial_virus_B R-HSA-4551638 SUMOylation of chromatin organization proteins 35/1832 71/10654 4.578117736399597e-10 3.2168582605233337e-9 1.6456615827371453e-9 23165/23468/5903/55706/7175/9631/6045/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/23512/57332/3066/3065/1107/8086/7329/9972/9063/8021/648/129401/55746/8480/8554 35 Human_respiratory_syncytial_virus_B R-HSA-109606 Intrinsic Pathway for Apoptosis 29/1832 53/10654 5.949196830415698e-10 4.158142334909597e-9 2.1271981983441256e-9 596/10018/1029/7027/842/572/7532/207/10971/5594/7533/841/1869/6774/54205/4836/598/836/10000/3002/7157/208/7161/331/581/5599/7159/317/5595 29 Human_respiratory_syncytial_virus_B R-HSA-8984722 Interleukin-35 Signalling 12/1832 12/10654 6.48583448852255e-10 4.462389249655358e-9 2.282843060104976e-9 10148/3592/6775/3595/821/6774/6772/3717/9466/3716/7297/3572 12 Human_respiratory_syncytial_virus_B R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 12/1832 12/10654 6.48583448852255e-10 4.462389249655358e-9 2.282843060104976e-9 3665/29110/7098/7316/3661/6233/10010/7311/7187/9641/7314/148022 12 Human_respiratory_syncytial_virus_B R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12/1832 12/10654 6.48583448852255e-10 4.462389249655358e-9 2.282843060104976e-9 1147/8737/57506/841/7706/8517/23586/843/64135/84282/8772/3551 12 Human_respiratory_syncytial_virus_B R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 24/1832 39/10654 6.865843898346801e-10 4.699367766692292e-9 2.404075147389499e-9 10694/26224/8841/2629/10575/10528/898/10517/7203/10576/908/6774/26272/26270/6950/55294/26190/7157/10574/6468/54461/22948/26234/84261 24 Human_respiratory_syncytial_virus_B R-HSA-5673001 RAF/MAP kinase cascade 82/1832 249/10654 7.624941445368192e-10 5.192034870789371e-9 2.6561109104321104e-9 5684/2674/4893/1437/3667/71/2065/3561/5525/5747/3815/5526/8844/1849/7010/1439/5594/2322/409/10817/2064/5921/1438/8452/5528/7316/10213/673/9978/3560/4233/84078/3718/6714/5715/5519/2261/5701/5688/3558/3717/2244/3084/2335/2534/3690/408/5529/1445/5710/4296/5894/3563/6233/5527/2885/6709/3716/5716/2266/8660/7311/5906/5518/5155/2243/1956/60/4254/5536/1843/3845/3265/3559/369/801/5696/5245/7314/5595/5515/5516 82 Human_respiratory_syncytial_virus_B R-HSA-392170 ADP signalling through P2Y purinoceptor 12 17/1832 22/10654 1.0341733557470865e-9 7.005861553548212e-9 3.5840177834797816e-9 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Human_respiratory_syncytial_virus_B R-HSA-877312 Regulation of IFNG signaling 13/1832 14/10654 1.306400072648606e-9 8.80486987739188e-9 4.504343966919468e-9 3460/5777/5770/9021/6772/8651/3459/3717/5771/3458/3716/5781/8554 13 Human_respiratory_syncytial_virus_B R-HSA-5673000 RAF activation 21/1832 32/10654 1.4684956026096592e-9 9.847120259123653e-9 5.037532337031265e-9 4893/5525/5526/8844/5528/673/6714/5519/3717/5529/4296/5894/5527/5518/3845/3265/369/801/5245/5515/5516 21 Human_respiratory_syncytial_virus_B R-HSA-1295596 Spry regulation of FGF signaling 14/1832 16/10654 1.6077212547935897e-9 1.066894702816024e-8 5.457957681245367e-9 5594/7316/673/6714/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 14 Human_respiratory_syncytial_virus_B R-HSA-1433559 Regulation of KIT signaling 14/1832 16/10654 1.6077212547935897e-9 1.066894702816024e-8 5.457957681245367e-9 5777/3815/10019/5578/9306/6714/8651/867/4067/2534/2885/7525/3932/4254 14 Human_respiratory_syncytial_virus_B R-HSA-1268020 Mitochondrial protein import 32/1832 64/10654 1.615283425913738e-9 1.066894702816024e-8 5.457957681245367e-9 90639/10063/131118/56942/10452/134266/26520/3313/7416/400916/10440/54927/10165/1678/3329/150274/56993/26521/25813/100272147/10469/4580/8604/26517/92609/10651/80273/9804/54543/388753/2671/131474 32 Human_respiratory_syncytial_virus_B R-HSA-73887 Death Receptor Signalling 54/1832 141/10654 1.6479684970421994e-9 1.0830678530312167e-8 5.540695339623419e-9 7124/1147/25999/81858/8841/7186/4790/6885/10018/572/8737/8767/55072/7375/9530/8878/355/330/23118/23385/841/27005/8517/4615/7316/5970/4792/5664/7128/329/843/836/23365/10616/10454/3066/3065/8567/3654/7189/6233/7410/7409/7311/387/8772/331/5599/1540/3551/8743/7314/5879/257397 54 Human_respiratory_syncytial_virus_B R-HSA-1236394 Signaling by ERBB4 30/1832 58/10654 1.8362412165065122e-9 1.200829033170843e-8 6.143131115149456e-9 5295/4893/5290/2670/2065/23118/51741/23385/348/6776/7316/9611/11059/4734/10413/6714/2099/5664/3084/83737/6285/6233/2885/7311/1956/3845/3265/11033/7314/6387 30 Human_respiratory_syncytial_virus_B R-HSA-983705 Signaling by the B Cell Receptor (BCR) 46/1832 112/10654 1.9263477802891696e-9 1.2535494668778291e-8 6.412835234356478e-9 5295/8454/1147/5777/8945/5684/4893/4790/6885/5579/5966/4690/5336/6500/930/8517/7316/10213/5970/4792/6850/4793/8915/5715/5701/5688/4067/29760/23291/2534/5710/695/5478/6233/2885/5716/7409/7311/5293/118788/3845/3265/3551/801/5696/7314 46 Human_respiratory_syncytial_virus_B R-HSA-114604 GPVI-mediated activation cascade 22/1832 35/10654 2.0008338357187156e-9 1.2956379887178546e-8 6.62814923906819e-9 5295/5170/5777/5590/5290/5291/5336/6850/8503/146850/4067/23533/5294/2534/998/7410/7409/3932/387/5296/5781/5879 22 Human_respiratory_syncytial_virus_B R-HSA-162906 HIV Infection 77/1832 233/10654 2.1067543567655315e-9 1.357571953798667e-8 6.944987404587785e-9 60489/23165/5905/8945/1173/3837/5684/5903/8065/7852/55706/7175/9631/3159/5430/6874/7520/4869/6500/348995/79023/57122/23636/10762/5431/23511/4686/7316/10213/9978/53371/920/292/3055/4836/23279/4927/9688/8148/79902/9150/5715/2962/23327/9883/5701/5688/5437/23225/2534/5710/8086/5478/3836/6827/6233/2968/5716/7514/163/1025/7311/9972/3932/6880/8021/129401/6829/2547/5062/55746/5696/8907/8480/940/7314/5879 77 Human_respiratory_syncytial_virus_B R-HSA-70171 Glycolysis 34/1832 71/10654 2.1470414398754434e-9 1.3768163796482819e-8 7.043436915687454e-9 23165/5903/2597/55706/7175/9631/348995/79023/57122/23636/5214/10762/23511/5528/53371/3098/23279/4927/9688/79902/5519/9883/2023/23225/5208/8086/9972/5518/8021/129401/55746/8480/5515/5516 34 Human_respiratory_syncytial_virus_B R-HSA-9614085 FOXO-mediated transcription 32/1832 65/10654 2.6609316519515175e-9 1.6981114551825866e-8 8.687099519719675e-9 2308/857/2309/65018/10018/7532/207/10971/4303/23410/1027/7295/4287/847/114907/4800/1026/84676/8850/9314/1387/4088/2908/10000/2033/3630/3066/3065/4087/56729/208/23411 32 Human_respiratory_syncytial_virus_B R-HSA-428930 Thromboxane signalling through TP receptor 17/1832 23/10654 3.3271640879166527e-9 2.1130691154509126e-8 1.080991571074135e-8 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Human_respiratory_syncytial_virus_B R-HSA-1059683 Interleukin-6 signaling 11/1832 11/10654 3.790704912759237e-9 2.3732327913530578e-8 1.2140845866756948e-8 9021/6774/6772/867/3717/3716/3570/7297/5781/3569/3572 11 Human_respiratory_syncytial_virus_B R-HSA-5603041 IRAK4 deficiency (TLR2/4) 11/1832 11/10654 3.790704912759237e-9 2.3732327913530578e-8 1.2140845866756948e-8 23643/10333/7099/4615/7096/929/114609/695/948/51135/7097 11 Human_respiratory_syncytial_virus_B R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 11/1832 11/10654 3.790704912759237e-9 2.3732327913530578e-8 1.2140845866756948e-8 6885/23118/7098/7316/10454/7189/6233/7311/7314/148022/257397 11 Human_respiratory_syncytial_virus_B R-HSA-8852135 Protein ubiquitination 36/1832 79/10654 3.963819277417211e-9 2.4699081440887433e-8 1.2635411996533512e-8 11065/7319/7321/65264/9646/7320/10477/92912/79577/7336/7326/5591/7323/7316/7317/54926/55236/8915/7415/3093/7322/7347/118424/7328/7324/6233/7327/7311/55284/27338/7334/7874/7332/3105/997/7314 36 Human_respiratory_syncytial_virus_B R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 38/1832 86/10654 4.303994939522304e-9 2.6568118294901702e-8 1.359156296691254e-8 8454/1017/8945/5684/11065/246184/7321/991/8697/9212/6500/8881/7316/10213/890/983/6790/51433/5715/5701/5688/6502/5710/51529/7324/64682/29945/10393/6233/51434/5716/51343/7311/5347/29882/5696/7314/996 38 Human_respiratory_syncytial_virus_B R-HSA-453276 Regulation of mitotic cell cycle 38/1832 86/10654 4.303994939522304e-9 2.6568118294901702e-8 1.359156296691254e-8 8454/1017/8945/5684/11065/246184/7321/991/8697/9212/6500/8881/7316/10213/890/983/6790/51433/5715/5701/5688/6502/5710/51529/7324/64682/29945/10393/6233/51434/5716/51343/7311/5347/29882/5696/7314/996 38 Human_respiratory_syncytial_virus_B R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 16/1832 21/10654 4.695428481562084e-9 2.8849586158807035e-8 1.4758702987333452e-8 1147/11035/4790/8737/29110/8517/4615/7098/5970/4792/4793/1660/3661/3551/4791/148022 16 Human_respiratory_syncytial_virus_B R-HSA-170834 Signaling by TGF-beta Receptor Complex 34/1832 73/10654 5.3243660642083816e-9 3.256244245749663e-8 1.6658104352932655e-8 57154/5590/892/7027/7321/6497/10273/4738/64750/7323/54778/7316/9611/5501/6667/4609/23327/867/7046/4088/142/3065/9958/9040/4087/5499/6233/7514/1025/7311/387/5500/7314/4221 34 Human_respiratory_syncytial_virus_B R-HSA-8848021 Signaling by PTK6 28/1832 54/10654 5.937836285723702e-9 3.5981108868995464e-8 1.8407005772257923e-8 120892/1017/4893/5770/2065/207/9021/1027/898/3091/2064/5921/7316/5753/6774/867/2908/3084/6233/1398/7311/2034/387/1956/3845/3265/7314/5879 28 Human_respiratory_syncytial_virus_B R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 28/1832 54/10654 5.937836285723702e-9 3.5981108868995464e-8 1.8407005772257923e-8 120892/1017/4893/5770/2065/207/9021/1027/898/3091/2064/5921/7316/5753/6774/867/2908/3084/6233/1398/7311/2034/387/1956/3845/3265/7314/5879 28 Human_respiratory_syncytial_virus_B R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 15/1832 19/10654 6.253419130541348e-9 3.754893941565964e-8 1.9209067377069596e-8 5295/4893/5290/5335/7316/867/3320/6233/2885/7311/1956/3845/3265/11140/7314 15 Human_respiratory_syncytial_virus_B R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 15/1832 19/10654 6.253419130541348e-9 3.754893941565964e-8 1.9209067377069596e-8 5295/4893/5290/5335/7316/867/3320/6233/2885/7311/1956/3845/3265/11140/7314 15 Human_respiratory_syncytial_virus_B R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 12/1832 13/10654 7.100532164253051e-9 4.225136481521748e-8 2.161470673044314e-8 2065/207/10193/9101/2064/7316/10000/3084/208/6233/7311/7314 12 Human_respiratory_syncytial_virus_B R-HSA-1679131 Trafficking and processing of endosomal TLR 12/1832 13/10654 7.100532164253051e-9 4.225136481521748e-8 2.161470673044314e-8 54106/10695/7184/7098/1513/5641/51311/1520/81622/1508/51284/1514 12 Human_respiratory_syncytial_virus_B R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 14/1832 17/10654 7.659782521333855e-9 4.5374765518753466e-8 2.3212557841379917e-8 1147/11035/4790/8737/8517/4615/7098/5970/4792/4793/1660/3551/4791/148022 14 Human_respiratory_syncytial_virus_B R-HSA-70326 Glucose metabolism 39/1832 91/10654 7.790514286829333e-9 4.594316684331049e-8 2.3503337275114813e-8 23165/5903/2597/55706/7175/9631/1468/8402/348995/79023/57122/23636/5214/10762/6576/23511/5528/53371/10165/3098/23279/4927/9688/79902/5519/9883/2023/23225/8604/5208/8086/9972/5518/8021/129401/55746/8480/5515/5516 39 Human_respiratory_syncytial_virus_B R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 34/1832 75/10654 1.2600609087298176e-8 7.397957601920396e-8 3.784603992535873e-8 23165/5903/6430/55706/7175/9631/6428/348995/79023/57122/23636/10762/23511/4686/53371/11338/7307/23279/4927/9688/79902/9883/10250/23225/10189/10482/8086/9972/8021/84248/129401/6427/55746/8480 34 Human_respiratory_syncytial_virus_B R-HSA-9006931 Signaling by Nuclear Receptors 90/1832 299/10654 1.7805923577319875e-8 1.0407798692760865e-7 5.3243609392824216e-8 5295/2788/5170/3725/596/5590/4893/8841/857/5290/54331/2309/5747/59345/5160/5430/207/64241/5594/1027/3315/10681/1737/51764/94235/4318/5481/200845/348/5431/2100/9611/865/55970/6667/2792/2289/6714/2099/4609/2962/8850/8503/1387/5437/2793/10000/3320/2033/5162/8243/2785/4846/9126/2783/4602/2784/2782/3065/861/23028/2786/208/10498/3326/7514/1385/1025/2353/1738/23030/1386/1956/5536/5296/4343/3845/3276/3265/801/29116/3480/2791/2288/10728/5595/2790/2787/7528/6387 90 Human_respiratory_syncytial_virus_B R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 25/1832 47/10654 1.9791478075190792e-8 1.1367192407533495e-7 5.815161979072077e-8 4893/71/8844/5594/409/673/6714/3717/2244/2335/3690/408/1445/4296/5894/2266/5906/2243/60/3845/3265/369/801/5245/5595 25 Human_respiratory_syncytial_virus_B R-HSA-6802949 Signaling by RAS mutants 25/1832 47/10654 1.9791478075190792e-8 1.1367192407533495e-7 5.815161979072077e-8 4893/71/8844/5594/409/673/6714/3717/2244/2335/3690/408/1445/4296/5894/2266/5906/2243/60/3845/3265/369/801/5245/5595 25 Human_respiratory_syncytial_virus_B R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 25/1832 47/10654 1.9791478075190792e-8 1.1367192407533495e-7 5.815161979072077e-8 4893/71/8844/5594/409/673/6714/3717/2244/2335/3690/408/1445/4296/5894/2266/5906/2243/60/3845/3265/369/801/5245/5595 25 Human_respiratory_syncytial_virus_B R-HSA-9649948 Signaling downstream of RAS mutants 25/1832 47/10654 1.9791478075190792e-8 1.1367192407533495e-7 5.815161979072077e-8 4893/71/8844/5594/409/673/6714/3717/2244/2335/3690/408/1445/4296/5894/2266/5906/2243/60/3845/3265/369/801/5245/5595 25 Human_respiratory_syncytial_virus_B R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 15/1832 20/10654 2.1019615709191453e-8 1.1968496703380132e-7 6.1227737229133e-8 11065/246184/7321/991/8697/8881/51433/51529/7324/64682/29945/10393/51434/29882/996 15 Human_respiratory_syncytial_virus_B R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 15/1832 20/10654 2.1019615709191453e-8 1.1968496703380132e-7 6.1227737229133e-8 11065/246184/7321/991/8697/8881/51433/51529/7324/64682/29945/10393/51434/29882/996 15 Human_respiratory_syncytial_virus_B R-HSA-2424491 DAP12 signaling 19/1832 30/10654 2.1600346422687304e-8 1.2246376662819712e-7 6.264929931495482e-8 5295/4893/5290/5335/7305/5291/5336/54209/6850/2534/695/2885/7410/3133/3932/5296/3845/3265/5879 19 Human_respiratory_syncytial_virus_B R-HSA-5602498 MyD88 deficiency (TLR2/4) 10/1832 10/10654 2.2145040116031427e-8 1.2448339571607453e-7 6.368248938182386e-8 23643/10333/7099/4615/7096/929/114609/695/948/7097 10 Human_respiratory_syncytial_virus_B R-HSA-937042 IRAK2 mediated activation of TAK1 complex 10/1832 10/10654 2.2145040116031427e-8 1.2448339571607453e-7 6.368248938182386e-8 6885/23118/7316/3656/10454/7189/6233/7311/7314/257397 10 Human_respiratory_syncytial_virus_B R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 35/1832 80/10654 2.3929412370791814e-8 1.3394387178735588e-7 6.85222245408044e-8 8454/1017/8945/5684/11065/246184/7321/991/8697/6500/8881/7316/10213/890/983/51433/5715/5701/5688/5710/51529/7324/64682/29945/10393/6233/51434/5716/51343/7311/5347/29882/5696/7314/996 35 Human_respiratory_syncytial_virus_B R-HSA-9609507 Protein localization 57/1832 163/10654 2.8128946878410505e-8 1.5678623977375645e-7 8.02077898997981e-8 1891/351/90639/9218/10063/7321/51/131118/10965/5621/56942/10452/134266/26520/8266/3313/7416/847/7323/7316/400916/10440/54927/10165/1678/3329/7322/150274/56993/1962/3416/26521/25813/100272147/118424/10469/4580/8604/4843/10455/26517/92609/10651/8540/6233/4358/6844/80273/9804/7311/54543/388753/2671/3162/6449/131474/7314 57 Human_respiratory_syncytial_virus_B R-HSA-69620 Cell Cycle Checkpoints 88/1832 293/10654 2.8783869135768277e-8 1.5976256776617602e-7 8.17304024111598e-8 1017/6118/5905/5684/5903/11065/246184/5525/1029/7321/991/5526/7532/8317/10971/8697/9212/51588/51720/1027/898/7533/348995/11200/545/79023/472/57122/7336/6232/580/8881/29086/5528/7316/10213/4174/993/5501/890/983/1026/4171/23279/51433/79902/5715/9656/5519/6119/9183/5701/5688/4683/1062/995/165918/5529/5710/7157/51529/7324/64682/29945/10393/8924/6233/5527/51434/5716/672/7514/7158/7311/5518/5347/5983/6117/29882/7334/51230/55746/5696/7314/996/4193/5515/5516 88 Human_respiratory_syncytial_virus_B R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 21/1832 36/10654 3.1272108519843785e-8 1.7284709353436668e-7 8.842410777247175e-8 4893/71/8844/5594/409/673/6714/2244/2335/3690/408/1445/5894/2266/5906/2243/60/3845/3265/369/5595 21 Human_respiratory_syncytial_virus_B R-HSA-418346 Platelet homeostasis 37/1832 88/10654 3.4785708342872125e-8 1.914663363372253e-7 9.794923138650836e-8 2788/5777/54331/5525/59345/5526/2977/10681/51764/94235/338/488/5528/55970/2778/2792/5519/1432/2793/4843/2785/4846/2783/2784/5529/2782/2786/5527/5518/801/5781/4842/2791/2790/5515/2787/5516 37 Human_respiratory_syncytial_virus_B R-HSA-193639 p75NTR signals via NF-kB 13/1832 16/10654 3.700179918412594e-8 2.0281899054867372e-7 1.0375695600003867e-7 4790/8767/8878/4615/7316/5970/4792/3654/7189/6233/7311/3551/7314 13 Human_respiratory_syncytial_virus_B R-HSA-1236975 Antigen processing-Cross presentation 40/1832 99/10654 3.7513366542308415e-8 2.0477337686937777e-7 1.0475676955268378e-7 23643/1147/3135/4688/5684/3107/6890/811/10333/7099/8517/4615/7316/10213/7096/3106/5715/5701/5688/929/114609/5710/695/6233/948/1520/4012/5716/3685/7311/3133/3134/7097/3551/1536/3105/5696/7314/4360/1514 40 Human_respiratory_syncytial_virus_B R-HSA-210990 PECAM1 interactions 11/1832 12/10654 3.835404101573581e-8 2.0595808203978459e-007 1.0536283411254767e-7 5777/3635/5335/6714/4067/2534/3690/7525/3685/3932/5781 11 Human_respiratory_syncytial_virus_B R-HSA-3371511 HSF1 activation 11/1832 12/10654 3.835404101573581e-8 2.0595808203978459e-007 1.0536283411254767e-7 6118/1915/10013/7415/6119/3281/3320/3326/6117/3297/10728 11 Human_respiratory_syncytial_virus_B R-HSA-9020558 Interleukin-2 signaling 11/1832 12/10654 3.835404101573581e-8 2.0595808203978459e-007 1.0536283411254767e-7 3561/6776/3560/6850/3718/3558/3716/3932/2185/6777/3559 11 Human_respiratory_syncytial_virus_B R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 11/1832 12/10654 3.835404101573581e-8 2.0595808203978459e-007 1.0536283411254767e-7 5295/5290/5291/4067/23533/3717/5294/2057/2056/8660/5293 11 Human_respiratory_syncytial_virus_B R-HSA-8943724 Regulation of PTEN gene transcription 29/1832 61/10654 4.001679172070763e-8 2.14016930619655e-7 1.0948553285614446e-7 3725/8841/5468/1822/23186/2146/5978/6045/5594/1108/64223/10014/1958/23512/57332/6009/6615/3066/3065/7157/1107/23028/2475/1386/8726/648/23466/57521/5595 29 Human_respiratory_syncytial_virus_B R-HSA-69242 S Phase 56/1832 161/10654 4.598282747859834e-8 2.449327221743081e-7 1.2530125314626542e-7 8454/1017/6118/5684/11065/246184/7027/7321/207/8697/1027/6500/898/8881/7316/10213/5422/9978/1869/4174/5753/993/890/1026/4171/4609/51433/5715/6119/2932/5701/5688/6502/10000/8243/9126/5710/51529/7324/64682/29945/10393/208/6233/51434/5716/55957/51343/7311/23649/5983/6117/29882/5696/7314/996 56 Human_respiratory_syncytial_virus_B R-HSA-2871837 FCERI mediated NF-kB activation 35/1832 82/10654 5.141209027554702e-8 2.7275249499597437e-7 1.3953313023420499e-7 8454/1147/5170/8945/5684/4790/6885/7321/6500/23118/8517/7316/10213/7335/5970/4792/8915/7322/5715/5701/5688/4067/23291/5710/10454/7189/6233/5716/7311/7334/3551/5696/997/7314/257397 35 Human_respiratory_syncytial_virus_B R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 32/1832 72/10654 6.023838401124966e-8 3.1829962111544317e-7 1.628338633061991e-7 5684/11065/246184/7321/991/8697/9212/8881/7316/10213/6790/51433/5715/5701/5688/6502/5710/51529/7324/64682/29945/10393/6233/51434/5716/51343/7311/5347/29882/5696/7314/996 32 Human_respiratory_syncytial_virus_B R-HSA-5654741 Signaling by FGFR3 22/1832 40/10654 6.348198780675675e-8 3.341024139152417e-7 1.709181638579905e-7 5295/4893/5290/5335/5594/10817/7316/673/6714/2261/867/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 22 Human_respiratory_syncytial_virus_B R-HSA-5205647 Mitophagy 18/1832 29/10654 8.065255516714381e-8 4.2278581498332134e-7 2.162863008241701e-7 65018/139341/1459/9140/8878/10452/7416/9474/192111/7316/1457/6714/56993/6233/9804/7311/54543/7314 18 Human_respiratory_syncytial_virus_B R-HSA-2173789 TGF-beta receptor signaling activates SMADs 19/1832 32/10654 9.665842682671993e-8 5.007285562278315e-7 2.561597936955797e-7 57154/10273/4738/64750/7316/5501/23327/867/7046/4088/9958/9040/4087/5499/6233/7514/7311/5500/7314 19 Human_respiratory_syncytial_virus_B R-HSA-2871796 FCERI mediated MAPK activation 19/1832 32/10654 9.665842682671993e-8 5.007285562278315e-7 2.561597936955797e-7 3725/4893/5335/5336/5594/4214/6850/4067/2885/7410/7409/2353/3845/5599/3265/6416/5062/5879/5595 19 Human_respiratory_syncytial_virus_B R-HSA-392518 Signal amplification 19/1832 32/10654 9.665842682671993e-8 5.007285562278315e-7 2.561597936955797e-7 2788/54331/59345/10681/51764/94235/55970/2792/6714/1432/2793/2785/2783/2784/2782/2786/2791/2790/2787 19 Human_respiratory_syncytial_virus_B R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 75/1832 244/10654 1.0799202688813398e-7 5.572557324969726e-7 2.8507763676884054e-7 10450/23165/22827/6635/5903/6633/6430/6632/55706/7175/9631/9129/23350/5430/4904/6428/3184/8106/3178/348995/79023/57122/23636/3183/10762/5431/9092/5093/23511/10594/4686/6625/10713/53371/11338/9343/3190/56339/7307/23279/4927/9688/79902/2962/988/9883/10236/5437/10250/23020/23225/10189/84844/10482/1660/8086/3191/6638/57721/27316/1665/9972/5094/8021/3192/84248/129401/6427/3312/55746/56259/5725/8480/10262/1994 75 Human_respiratory_syncytial_virus_B R-HSA-5696394 DNA Damage Recognition in GG-NER 21/1832 38/10654 1.1360908590164978e-7 5.8395954270848e-7 2.9873861621486446e-7 9318/86/8450/7316/9978/64708/10980/10920/142/10987/6233/2873/7311/60/8533/8607/50813/7314/51138/8451/7528 21 Human_respiratory_syncytial_virus_B R-HSA-447115 Interleukin-12 family signaling 27/1832 57/10654 1.2903029326734063e-7 6.606551062254147e-7 3.3797408518005993e-7 10148/3592/3593/6775/3595/821/4478/3313/6175/6774/6772/6647/149233/6950/3717/9466/3458/998/5478/3716/3594/51561/246778/7297/5062/3586/3572 27 Human_respiratory_syncytial_virus_B R-HSA-432142 Platelet sensitization by LDL 13/1832 17/10654 1.3236335333820029e-7 6.751042075666509e-7 3.4536587215250795e-7 5777/5525/5526/338/5528/5519/1432/5529/5527/5518/5781/5515/5516 13 Human_respiratory_syncytial_virus_B R-HSA-6802957 Oncogenic MAPK signaling 31/1832 71/10654 1.5890439521608674e-7 8.073565618478868e-7 4.130227600353348e-7 4000/4893/71/10018/55750/8844/5594/409/10533/673/57085/6714/3717/2244/2335/3690/408/1445/4296/5894/2266/56829/5906/2243/60/3845/3265/369/801/5245/5595 31 Human_respiratory_syncytial_virus_B R-HSA-6804758 Regulation of TP53 Activity through Acetylation 18/1832 30/10654 1.6923086828382892e-7 8.565286475208352e-7 4.3817792876877666e-7 23774/64769/7862/207/84289/1108/27154/10000/2033/7994/3066/3065/7157/1107/5371/208/5300/5608 18 Human_respiratory_syncytial_virus_B R-HSA-1170546 Prolactin receptor signaling 12/1832 15/10654 1.7635018010322524e-7 8.692484623744795e-7 4.446850574480385e-7 8454/8945/2690/6500/6776/9978/3717/5618/2688/6777/2689/5781 12 Human_respiratory_syncytial_virus_B R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 12/1832 15/10654 1.7635018010322524e-7 8.692484623744795e-7 4.446850574480385e-7 1499/5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 12 Human_respiratory_syncytial_virus_B R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 12/1832 15/10654 1.7635018010322524e-7 8.692484623744795e-7 4.446850574480385e-7 1499/5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 12 Human_respiratory_syncytial_virus_B R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 12/1832 15/10654 1.7635018010322524e-7 8.692484623744795e-7 4.446850574480385e-7 1499/5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 12 Human_respiratory_syncytial_virus_B R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 12/1832 15/10654 1.7635018010322524e-7 8.692484623744795e-7 4.446850574480385e-7 1499/5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 12 Human_respiratory_syncytial_virus_B R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 12/1832 15/10654 1.7635018010322524e-7 8.692484623744795e-7 4.446850574480385e-7 1499/5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 12 Human_respiratory_syncytial_virus_B R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 12/1832 15/10654 1.7635018010322524e-7 8.692484623744795e-7 4.446850574480385e-7 1499/5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 12 Human_respiratory_syncytial_virus_B R-HSA-420092 Glucagon-type ligand receptors 19/1832 33/10654 1.9115470411136612e-7 9.387188257662254e-7 4.802243006828294e-7 2788/2692/54331/59345/10681/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 19 Human_respiratory_syncytial_virus_B R-HSA-2586552 Signaling by Leptin 10/1832 11/10654 2.0568839214875344e-7 1.0026360370055473e-6 5.129226947348988e-7 3667/3953/9021/3952/6776/6774/3717/8660/6777/5781 10 Human_respiratory_syncytial_virus_B R-HSA-9020956 Interleukin-27 signaling 10/1832 11/10654 2.0568839214875344e-7 1.0026360370055473e-6 5.129226947348988e-7 10148/821/6774/6772/3717/9466/3716/246778/7297/3572 10 Human_respiratory_syncytial_virus_B R-HSA-209560 NF-kB is activated and signals survival 11/1832 13/10654 2.1024833969889231e-7 1.0210957968464585e-6 5.22366230985638e-7 4790/8878/7316/5970/4792/3654/7189/6233/7311/3551/7314 11 Human_respiratory_syncytial_virus_B R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 35/1832 86/10654 2.137546837440572e-7 1.0343221143805843e-6 5.291324733513967e-7 5295/25/3984/5290/5335/71/5291/5747/4690/5336/4771/5594/4644/3055/6850/4641/6714/4067/3320/2534/998/695/2885/7525/1398/7410/10096/3326/5580/7409/23191/60/5296/5879/5595 35 Human_respiratory_syncytial_virus_B R-HSA-69052 Switching of origins to a post-replicative state 36/1832 90/10654 2.4077495231172625e-7 1.1608164671671182e-6 5.938437164200087e-7 8454/1017/5684/11065/246184/7321/8697/6500/898/8881/7316/10213/9978/4174/890/4171/51433/5715/5701/5688/6502/5710/51529/7324/64682/29945/10393/6233/51434/5716/51343/7311/29882/5696/7314/996 36 Human_respiratory_syncytial_virus_B R-HSA-162587 HIV Life Cycle 52/1832 152/10654 2.5272021515958534e-7 1.21397601536659e-6 6.21038767971115e-7 23165/5905/5903/7852/55706/7175/9631/3159/5430/6874/7520/348995/79023/57122/23636/10762/5431/23511/4686/7316/53371/920/4836/23279/4927/9688/8148/79902/9150/2962/23327/9883/5437/23225/8086/5478/3836/6827/6233/2968/7514/1025/7311/9972/6880/8021/129401/6829/2547/55746/8480/7314 52 Human_respiratory_syncytial_virus_B R-HSA-5213460 RIPK1-mediated regulated necrosis 14/1832 20/10654 2.5973167151036116e-7 1.234192582968299e-6 6.31381041687436e-7 11035/7186/8737/355/330/841/7316/329/6233/7311/8772/331/8743/7314 14 Human_respiratory_syncytial_virus_B R-HSA-5218859 Regulated Necrosis 14/1832 20/10654 2.5973167151036116e-7 1.234192582968299e-6 6.31381041687436e-7 11035/7186/8737/355/330/841/7316/329/6233/7311/8772/331/8743/7314 14 Human_respiratory_syncytial_virus_B R-HSA-622312 Inflammasomes 14/1832 20/10654 2.5973167151036116e-7 1.234192582968299e-6 6.31381041687436e-7 834/9447/596/351/4790/10910/58484/7295/29108/5970/598/3326/114548/4791 14 Human_respiratory_syncytial_virus_B R-HSA-202040 G-protein activation 17/1832 28/10654 2.952195718362286e-7 1.3928037656987785e-6 7.125224252588674e-7 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Human_respiratory_syncytial_virus_B R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 17/1832 28/10654 2.952195718362286e-7 1.3928037656987785e-6 7.125224252588674e-7 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Human_respiratory_syncytial_virus_B R-HSA-453279 Mitotic G1-G1/S phases 51/1832 149/10654 3.229194251892222e-7 1.5180660522240658e-006 7.766033750570543e-7 8454/1017/6118/25/5684/1029/7027/8317/207/1027/6500/898/7316/10213/5422/1869/4174/5753/993/890/983/1026/6714/4171/4609/1031/5715/5519/6119/5701/5688/4067/3717/6502/10000/5710/3065/208/6233/5716/55957/7311/5518/23649/6117/1859/5696/7314/5515/6241/5516 51 Human_respiratory_syncytial_virus_B R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 18/1832 31/10654 3.387400214112881e-7 1.5867927953344383e-6 8.117622013663567e-7 3725/1849/5594/5528/5519/5598/1432/1385/2353/5518/1386/6197/5599/5600/51231/5595/5515/5516 18 Human_respiratory_syncytial_virus_B R-HSA-5674135 MAP2K and MAPK activation 21/1832 40/10654 3.6433145187665597e-7 1.7006425721875002e-6 8.700048060435676e-7 4893/71/8844/5594/409/673/6714/2244/2335/3690/408/1445/5894/2266/5906/2243/60/3845/3265/369/5595 21 Human_respiratory_syncytial_virus_B R-HSA-72202 Transport of Mature Transcript to Cytoplasm 34/1832 84/10654 3.7092251873071586e-7 1.725312138180548e-6 8.826251186994796e-7 23165/5903/6430/55706/7175/9631/6428/348995/79023/57122/23636/10762/23511/4686/53371/11338/7307/23279/4927/9688/79902/9883/10250/23225/10189/10482/8086/9972/8021/84248/129401/6427/55746/8480 34 Human_respiratory_syncytial_virus_B R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 15/1832 23/10654 3.947854765915083e-7 1.8298653143066052e-6 9.361118226103354e-7 7321/6497/64750/7323/54778/7316/9611/23327/4088/142/3065/4087/6233/7311/7314 15 Human_respiratory_syncytial_virus_B R-HSA-72766 Translation 84/1832 291/10654 3.979876362214688e-7 1.8382575784914698e-6 9.40405088164089e-7 6158/6138/6144/6203/9349/6206/6194/6191/6128/51121/6132/65993/1938/6147/8666/6129/1915/6217/6222/6176/6152/6136/27068/6125/6727/7818/6224/6146/6141/26986/6202/64949/6232/6160/55699/6155/6748/8661/6175/6218/9669/6209/6193/6231/6229/6165/6130/6142/6204/51081/8663/6228/23521/8894/7965/1981/6143/6124/6207/6139/6745/6233/7311/6223/25873/8664/51386/3921/6188/6189/10102/6135/6201/1978/9045/6187/6168/6208/6157/6137/7284/6122/6133/6230 84 Human_respiratory_syncytial_virus_B R-HSA-5675482 Regulation of necroptotic cell death 13/1832 18/10654 4.011472047440594e-7 1.8463953221843292e-6 9.445681476093386e-7 7186/8737/355/330/841/7316/329/6233/7311/8772/331/8743/7314 13 Human_respiratory_syncytial_virus_B R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 35/1832 88/10654 4.1543779124471115e-7 1.9055323688689702e-6 9.748211329645634e-7 5393/3303/5684/23404/3842/207/5578/3184/3315/26986/7538/7316/10213/5715/1432/5701/5688/1981/5710/6233/5580/5716/7514/7311/8021/54464/5600/3304/3312/54512/5696/167227/22894/7314/1994 35 Human_respiratory_syncytial_virus_B R-HSA-6802952 Signaling by BRAF and RAF fusions 29/1832 67/10654 4.97366281465741e-7 2.2734285737586293e-6 1.163027327266457e-6 4000/4893/71/10018/55750/8844/5594/409/10533/673/57085/6714/3717/2244/2335/3690/408/1445/5894/2266/56829/5906/2243/60/3845/3265/369/801/5595 29 Human_respiratory_syncytial_virus_B R-HSA-2173788 Downregulation of TGF-beta receptor signaling 16/1832 26/10654 5.126722236862643e-7 2.3353103706536384e-6 1.1946844559222565e-6 57154/10273/64750/7316/5501/23327/7046/4088/9958/4087/5499/6233/7514/7311/5500/7314 16 Human_respiratory_syncytial_virus_B R-HSA-69231 Cyclin D associated events in G1 22/1832 44/10654 5.816227175823797e-7 2.631245239473711e-6 1.346077089718413e-6 8454/25/1029/7027/1027/6500/7316/1869/5753/1026/6714/1031/5519/4067/3717/6502/6233/7311/5518/7314/5515/5516 22 Human_respiratory_syncytial_virus_B R-HSA-69236 G1 Phase 22/1832 44/10654 5.816227175823797e-7 2.631245239473711e-6 1.346077089718413e-6 8454/25/1029/7027/1027/6500/7316/1869/5753/1026/6714/1031/5519/4067/3717/6502/6233/7311/5518/7314/5515/5516 22 Human_respiratory_syncytial_virus_B R-HSA-8863795 Downregulation of ERBB2 signaling 17/1832 29/10654 5.991895121174338e-7 2.7014653430277476e-6 1.3819998806516706e-6 8065/2065/10273/207/10193/9101/2064/7316/10000/3320/3084/208/6233/7311/1956/11140/7314 17 Human_respiratory_syncytial_virus_B R-HSA-5654743 Signaling by FGFR4 21/1832 41/10654 6.263247365777733e-7 2.8142006021062535e-6 1.4396723268275348e-6 5295/4893/5290/5335/5594/10817/7316/673/6714/867/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 21 Human_respiratory_syncytial_virus_B R-HSA-451326 Activation of kainate receptors upon glutamate binding 18/1832 32/10654 6.499877858771657e-7 2.910623271673681e-6 1.4889996736240511e-6 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/801/2791/2790/2787 18 Human_respiratory_syncytial_virus_B R-HSA-5621575 CD209 (DC-SIGN) signaling 14/1832 21/10654 6.555348469745504e-7 2.92554571909926e-6 1.4966336122249691e-6 4893/4790/3384/5970/1387/4067/2534/2033/3385/5894/30835/3845/3265/5062 14 Human_respiratory_syncytial_virus_B R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 31/1832 75/10654 6.977470843647848e-7 3.1034474695147503e-6 1.5876435518773414e-6 5295/5290/3667/5291/2065/3815/930/941/2064/2100/4233/6714/2099/8503/2261/3084/2534/942/2885/7409/8660/3932/5293/5155/1956/4254/118788/5296/5781/940/5879 31 Human_respiratory_syncytial_virus_B R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 11/1832 14/10654 8.276527279772748e-7 3.5964778080854607e-6 1.8398651362929725e-6 5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 11 Human_respiratory_syncytial_virus_B R-HSA-4839744 truncated APC mutants destabilize the destruction complex 11/1832 14/10654 8.276527279772748e-7 3.5964778080854607e-6 1.8398651362929725e-6 5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 11 Human_respiratory_syncytial_virus_B R-HSA-4839748 AMER1 mutants destabilize the destruction complex 11/1832 14/10654 8.276527279772748e-7 3.5964778080854607e-6 1.8398651362929725e-6 5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 11 Human_respiratory_syncytial_virus_B R-HSA-5467337 APC truncation mutants have impaired AXIN binding 11/1832 14/10654 8.276527279772748e-7 3.5964778080854607e-6 1.8398651362929725e-6 5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 11 Human_respiratory_syncytial_virus_B R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 11/1832 14/10654 8.276527279772748e-7 3.5964778080854607e-6 1.8398651362929725e-6 5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 11 Human_respiratory_syncytial_virus_B R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 11/1832 14/10654 8.276527279772748e-7 3.5964778080854607e-6 1.8398651362929725e-6 5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 11 Human_respiratory_syncytial_virus_B R-HSA-9027284 Erythropoietin activates RAS 11/1832 14/10654 8.276527279772748e-7 3.5964778080854607e-6 1.8398651362929725e-6 4893/4067/3717/2057/2885/2056/7409/8660/3845/3265/1399 11 Human_respiratory_syncytial_virus_B R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 30/1832 72/10654 8.566916929890441e-7 3.7104581194705815e-6 1.8981745190645944e-6 1017/5684/11065/246184/7321/8697/898/8881/7316/10213/890/51433/5715/5701/5688/5710/51529/7324/64682/29945/10393/6233/51434/5716/51343/7311/29882/5696/7314/996 30 Human_respiratory_syncytial_virus_B R-HSA-1236974 ER-Phagosome pathway 33/1832 83/10654 8.926110631005359e-7 3.853396125345777e-6 1.971297910252989e-6 23643/1147/3135/5684/3107/6890/811/10333/7099/8517/4615/7316/10213/7096/3106/5715/5701/5688/929/114609/5710/695/6233/948/5716/7311/3133/3134/7097/3551/3105/5696/7314 33 Human_respiratory_syncytial_virus_B R-HSA-389359 CD28 dependent Vav1 pathway 10/1832 12/10654 1.042360147813839e-6 4.485204414534466e-6 2.2945147090570363e-6 941/2534/998/942/2885/7409/3932/5062/940/5879 10 Human_respiratory_syncytial_virus_B R-HSA-110056 MAPK3 (ERK1) activation 9/1832 10/10654 1.0938046336630923e-6 4.646031900543231e-6 2.3767898961303275e-6 983/3717/3716/3570/7297/5781/3569/3572/5595 9 Human_respiratory_syncytial_virus_B R-HSA-2562578 TRIF-mediated programmed cell death 9/1832 10/10654 1.0938046336630923e-6 4.646031900543231e-6 2.3767898961303275e-6 23643/11035/8737/841/7099/929/8772/353376/148022 9 Human_respiratory_syncytial_virus_B R-HSA-390450 Folding of actin by CCT/TriC 9/1832 10/10654 1.0938046336630923e-6 4.646031900543231e-6 2.3767898961303275e-6 10694/10575/7203/10576/908/6950/10574/60/22948 9 Human_respiratory_syncytial_virus_B R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 9/1832 10/10654 1.0938046336630923e-6 4.646031900543231e-6 2.3767898961303275e-6 2308/2309/4303/23410/7295/8850/1387/2033/23411 9 Human_respiratory_syncytial_virus_B R-HSA-69239 Synthesis of DNA 42/1832 119/10654 1.395473404362747e-6 5.908398612702528e-6 3.022584094469918e-6 8454/1017/6118/5684/11065/246184/7321/8697/6500/898/8881/7316/10213/5422/9978/4174/890/4171/51433/5715/6119/5701/5688/6502/5710/51529/7324/64682/29945/10393/6233/51434/5716/51343/7311/23649/5983/6117/29882/5696/7314/996 42 Human_respiratory_syncytial_virus_B R-HSA-69306 DNA Replication 44/1832 127/10654 1.409326400616858e-6 5.947987780239199e-6 3.042836889847058e-6 8454/1017/6118/5684/11065/246184/7321/8317/8697/6500/898/8881/7316/10213/5422/9978/1869/4174/890/4171/51433/5715/6119/5701/5688/6502/5710/51529/7324/64682/29945/10393/6233/51434/5716/51343/7311/23649/5983/6117/29882/5696/7314/996 44 Human_respiratory_syncytial_virus_B R-HSA-9613829 Chaperone Mediated Autophagy 14/1832 22/10654 1.5168757764635759e-6 6.381506053211412e-6 3.2646136389192613e-6 2670/1915/1080/10013/7316/3920/3320/6233/3326/7311/7431/3312/11315/7314 14 Human_respiratory_syncytial_virus_B R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 27/1832 63/10654 1.5520445024905653e-6 6.50873265965091e-6 3.329699484039909e-6 5684/11065/246184/7321/8697/8881/7316/10213/51433/5715/5701/5688/5710/51529/7324/64682/29945/10393/6233/51434/5716/51343/7311/29882/5696/7314/996 27 Human_respiratory_syncytial_virus_B R-HSA-196299 Beta-catenin phosphorylation cascade 12/1832 17/10654 1.7032720497140945e-6 7.120323979975692e-6 3.6425738038522604e-6 1499/5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 12 Human_respiratory_syncytial_virus_B R-HSA-1643713 Signaling by EGFR in Cancer 15/1832 25/10654 1.8609068403901337e-6 7.75475689638917e-6 3.96713329414068e-6 5295/4893/5290/5335/7316/867/3320/6233/2885/7311/1956/3845/3265/11140/7314 15 Human_respiratory_syncytial_virus_B R-HSA-8878166 Transcriptional regulation by RUNX2 42/1832 121/10654 2.2987807865919565e-6 9.549337795874134e-6 4.8851945216552005e-6 8454/57154/25/5684/8841/10273/207/5594/3280/6500/10013/7316/10213/9978/865/11059/983/1026/10413/6772/6714/2099/5715/2932/5701/5688/6502/2908/10000/55294/5710/861/208/6233/7525/5716/7311/367/581/5696/7314/5595 42 Human_respiratory_syncytial_virus_B R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 22/1832 47/10654 2.417136254121803e-6 1.0009520350140758e-5 5.120612028200619e-6 8454/8841/892/55869/3280/6500/3091/10013/7316/9978/9611/4609/10014/8850/1387/2033/55294/3066/3065/6233/7311/7314 22 Human_respiratory_syncytial_virus_B R-HSA-5637810 Constitutive Signaling by EGFRvIII 11/1832 15/10654 2.61873473463089e-6 1.0710057536988873e-5 5.478988755525604e-6 5295/4893/5290/5335/867/3320/2885/1956/3845/3265/11140 11 Human_respiratory_syncytial_virus_B R-HSA-5637812 Signaling by EGFRvIII in Cancer 11/1832 15/10654 2.61873473463089e-6 1.0710057536988873e-5 5.478988755525604e-6 5295/4893/5290/5335/867/3320/2885/1956/3845/3265/11140 11 Human_respiratory_syncytial_virus_B R-HSA-937039 IRAK1 recruits IKK complex 11/1832 15/10654 2.61873473463089e-6 1.0710057536988873e-5 5.478988755525604e-6 1147/8517/7316/7335/3654/7189/6233/7311/7334/3551/7314 11 Human_respiratory_syncytial_virus_B R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 11/1832 15/10654 2.61873473463089e-6 1.0710057536988873e-5 5.478988755525604e-6 1147/8517/7316/7335/3654/7189/6233/7311/7334/3551/7314 11 Human_respiratory_syncytial_virus_B R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 21/1832 44/10654 2.7636474557355054e-6 1.126783422539075e-5 5.764332899877175e-6 892/7027/7321/6497/64750/7323/54778/7316/9611/6667/4609/23327/4088/142/3065/4087/6233/1025/7311/7314/4221 21 Human_respiratory_syncytial_virus_B R-HSA-9006936 Signaling by TGF-beta family members 37/1832 102/10654 2.7760065645378056e-6 1.1283398990013666e-5 5.772295431362821e-6 57154/5590/892/7027/11167/7321/6497/10273/4738/64750/7323/54778/7316/9611/5501/6667/4609/23327/867/7046/92/4088/142/3065/9958/9040/4087/5499/657/6233/7514/1025/7311/387/5500/7314/4221 37 Human_respiratory_syncytial_virus_B R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 32/1832 83/10654 2.8750445803511247e-6 1.1650103959030171e-5 5.959892220166038e-6 8454/1147/8945/5684/4893/4790/6885/5579/5966/6500/8517/7316/10213/5970/4792/4793/8915/5715/5701/5688/23291/5710/5478/6233/5716/7311/3845/3265/3551/801/5696/7314 32 Human_respiratory_syncytial_virus_B R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 29/1832 72/10654 2.9739282945179767e-6 1.2013942743297392e-5 6.146022742895674e-6 5684/11065/246184/7321/991/8697/8881/7316/10213/890/983/51433/5715/5701/5688/5710/51529/7324/64682/29945/10393/6233/51434/5716/7311/29882/5696/7314/996 29 Human_respiratory_syncytial_virus_B R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 30/1832 76/10654 3.3079927933436255e-6 1.3322739268313809e-5 6.8155692340391766e-6 5684/11065/246184/7321/991/8697/8881/7316/10213/890/983/51433/5715/5701/5688/5710/51529/7324/64682/29945/10393/6233/51434/5716/7311/5347/29882/5696/7314/996 30 Human_respiratory_syncytial_virus_B R-HSA-162599 Late Phase of HIV Life Cycle 46/1832 139/10654 3.472321927563009e-6 1.3942058560215001e-5 7.13239698446793e-6 23165/5905/5903/55706/7175/9631/5430/6874/348995/79023/57122/23636/10762/5431/23511/4686/7316/53371/4836/23279/4927/9688/8148/79902/9150/2962/23327/9883/5437/23225/8086/5478/6827/6233/2968/7514/1025/7311/9972/6880/8021/129401/6829/55746/8480/7314 46 Human_respiratory_syncytial_virus_B R-HSA-69206 G1/S Transition 44/1832 131/10654 3.6240007041421935e-6 1.4506984636884356e-5 7.421398571162004e-6 8454/1017/6118/5684/7027/8317/207/1027/6500/898/7316/10213/5422/1869/4174/5753/993/890/983/1026/4171/4609/5715/5519/6119/5701/5688/6502/10000/5710/3065/208/6233/5716/55957/7311/5518/23649/6117/5696/7314/5515/6241/5516 44 Human_respiratory_syncytial_virus_B R-HSA-418597 G alpha (z) signalling events 22/1832 48/10654 3.7422637924470527e-6 1.4858827901167058e-5 7.601392495756205e-6 2788/54331/5579/59345/5578/5582/10681/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/5580/2791/2790/2787 22 Human_respiratory_syncytial_virus_B R-HSA-73893 DNA Damage Bypass 22/1832 48/10654 3.7422637924470527e-6 1.4858827901167058e-5 7.601392495756205e-6 6118/7320/9636/7706/8450/7316/9978/10459/7415/6119/25898/7398/9246/57599/6233/7311/7318/5983/6117/7314/51514/8451 22 Human_respiratory_syncytial_virus_B R-HSA-9612973 Autophagy 41/1832 119/10654 3.745639433072392e-6 1.4858827901167058e-5 7.601392495756205e-6 2670/65018/139341/1459/1915/9140/8878/10452/7249/1080/10533/10013/64419/7416/9474/192111/7316/1457/8678/6714/64223/56993/3920/3320/6009/55054/6233/3326/2475/9804/7311/54543/5562/55626/7431/3312/5564/11315/57521/7248/7314 41 Human_respiratory_syncytial_virus_B R-HSA-202670 ERKs are inactivated 10/1832 13/10654 3.816066174863658e-6 1.504783109550714e-5 7.698081647329044e-6 1849/5594/5528/5519/5598/5518/51231/5595/5515/5516 10 Human_respiratory_syncytial_virus_B R-HSA-209543 p75NTR recruits signalling complexes 10/1832 13/10654 3.816066174863658e-6 1.504783109550714e-5 7.698081647329044e-6 8767/8878/4615/7316/3654/7189/6233/7311/3551/7314 10 Human_respiratory_syncytial_virus_B R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 32/1832 84/10654 3.887272482801454e-6 1.5282996874347383e-5 7.818386384581872e-6 9318/6118/7336/86/8450/54778/7316/9978/64708/10980/6119/10401/10920/142/10987/7329/6233/2873/2968/7311/60/8533/8607/5983/6117/7334/50813/7314/51138/8451/8554/7528 32 Human_respiratory_syncytial_virus_B R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 29/1832 73/10654 4.131617560208935e-6 1.6147534902473382e-5 8.260661705556326e-6 5684/11065/246184/7321/991/8697/8881/7316/10213/890/983/51433/5715/5701/5688/5710/51529/7324/64682/29945/10393/6233/51434/5716/7311/29882/5696/7314/996 29 Human_respiratory_syncytial_virus_B R-HSA-5654738 Signaling by FGFR2 29/1832 73/10654 4.131617560208935e-6 1.6147534902473382e-5 8.260661705556326e-6 5295/4893/5290/5335/5430/5594/3178/10817/5431/4686/7316/673/6714/2962/867/5437/7072/6233/2885/7311/5518/3845/3265/5781/5725/7314/5595/5515/5516 29 Human_respiratory_syncytial_virus_B R-HSA-8878159 Transcriptional regulation by RUNX3 35/1832 96/10654 4.488775855552067e-6 1.7491660487269263e-5 8.948281631002722e-6 57154/5684/2309/1499/10018/1029/3280/64750/7316/10213/865/1026/10413/6714/6934/4609/5715/8850/5701/5688/1387/7005/4088/2033/5710/7157/861/6233/5716/7311/3845/5696/3676/7314/4193 35 Human_respiratory_syncytial_virus_B R-HSA-69618 Mitotic Spindle Checkpoint 39/1832 112/10654 4.789128313346836e-6 1.8607172064503443e-5 9.518948536125912e-6 5905/5903/11065/246184/5525/7321/991/5526/8697/9212/348995/79023/57122/6232/8881/5528/5501/23279/51433/79902/5519/9183/1062/5529/51529/7324/64682/29945/10393/5527/51434/7514/5518/5347/29882/55746/996/5515/5516 39 Human_respiratory_syncytial_virus_B R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 20/1832 42/10654 4.984225304833321e-6 1.9308391870043453e-5 9.877674473539103e-6 2788/54331/59345/10681/51764/94235/55970/2778/2792/2793/2785/2783/2784/9495/2782/2786/5906/2791/2790/2787 20 Human_respiratory_syncytial_virus_B R-HSA-1236977 Endosomal/Vacuolar pathway 9/1832 11/10654 5.090327720477633e-6 1.9604439996358464e-5 1.002912504694381e-5 3135/3107/3106/1520/4012/3133/3134/3105/1514 9 Human_respiratory_syncytial_virus_B R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 9/1832 11/10654 5.090327720477633e-6 1.9604439996358464e-5 1.002912504694381e-5 6885/23118/7316/10454/7189/6233/7311/7314/257397 9 Human_respiratory_syncytial_virus_B R-HSA-5218921 VEGFR2 mediated cell proliferation 13/1832 21/10654 5.6905200604196924e-6 2.1852258720390736e-5 1.1179051036687401e-5 5170/5590/4893/5335/5579/7422/5578/5921/6714/5580/3845/3265/801 13 Human_respiratory_syncytial_virus_B R-HSA-3858494 Beta-catenin independent WNT signaling 47/1832 146/10654 6.398011962709277e-6 2.4397323451841256e-5 1.2481040404862415e-5 2788/57154/1173/5684/54331/6885/5579/1499/59345/5578/5582/10681/409/51764/94235/64750/7316/10213/55970/5216/2792/6934/5715/5701/5688/2793/2785/2783/2784/5710/2782/2786/6233/5716/163/7311/1213/387/4343/3845/801/2791/5696/7314/5879/2790/2787 47 Human_respiratory_syncytial_virus_B R-HSA-1169091 Activation of NF-kappaB in B cells 27/1832 67/10654 6.408683753057469e-6 2.4397323451841256e-5 1.2481040404862415e-5 8454/1147/8945/5684/4790/6885/5579/5966/6500/8517/7316/10213/5970/4792/4793/8915/5715/5701/5688/23291/5710/6233/5716/7311/3551/5696/7314 27 Human_respiratory_syncytial_virus_B R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 27/1832 67/10654 6.408683753057469e-6 2.4397323451841256e-5 1.2481040404862415e-5 5684/11065/246184/7321/991/8697/8881/7316/10213/51433/5715/5701/5688/5710/51529/7324/64682/29945/10393/6233/51434/5716/7311/29882/5696/7314/996 27 Human_respiratory_syncytial_virus_B R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 14/1832 24/10654 6.5904070849265875e-6 2.5017033790770178e-5 1.2798068204848363e-5 4688/5590/5579/5578/5594/6280/6279/1432/5580/5300/5600/1536/5879/5595 14 Human_respiratory_syncytial_virus_B R-HSA-354192 Integrin alphaIIb beta3 signaling 15/1832 27/10654 7.001809574571815e-6 2.6426829851455335e-5 1.3519283449248436e-5 5170/5770/5747/207/6850/6714/2244/2335/3690/1445/2885/1398/2266/5906/2243 15 Human_respiratory_syncytial_virus_B R-HSA-9006921 Integrin signaling 15/1832 27/10654 7.001809574571815e-6 2.6426829851455335e-5 1.3519283449248436e-5 5170/5770/5747/207/6850/6714/2244/2335/3690/1445/2885/1398/2266/5906/2243 15 Human_respiratory_syncytial_virus_B R-HSA-73894 DNA Repair 89/1832 334/10654 7.253509989304925e-6 2.729882249536127e-5 1.3965372359075608e-5 10450/9318/8467/1017/7014/6118/2176/25/5893/5888/328/5430/7320/51588/7520/51720/2956/7013/5531/4292/9636/11200/545/472/7706/7336/86/580/5431/5591/29086/8450/54778/7316/9978/890/64708/10459/7415/7517/10980/9656/6119/4683/5437/10401/10920/25898/2033/165918/142/7398/10987/7157/55215/7329/4255/9246/8924/57599/6233/2873/2968/672/7158/7311/6047/7318/23030/60/5536/8533/8607/5983/6117/5599/7334/10973/7874/2547/54386/4437/50813/7314/51514/51138/8451/8554/7528 89 Human_respiratory_syncytial_virus_B R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 29/1832 75/10654 7.768875421858164e-6 2.915535350078021e-5 1.4915125660385589e-5 5684/11065/246184/7321/991/8697/8881/7316/10213/890/983/51433/5715/5701/5688/5710/51529/7324/64682/29945/10393/6233/51434/5716/7311/29882/5696/7314/996 29 Human_respiratory_syncytial_virus_B R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 38/1832 110/10654 7.81759527612814e-6 2.9184196060992518e-5 1.49298807690802e-5 1017/3725/11065/4790/246184/1029/7321/8697/5594/1027/3576/8881/7316/890/6774/5970/1026/51433/1031/5598/3552/51529/7324/64682/29945/10393/6233/51434/2353/51343/7311/6197/29882/3569/10919/7314/996/5595 38 Human_respiratory_syncytial_virus_B R-HSA-2172127 DAP12 interactions 20/1832 43/10654 7.820745954270516e-6 2.9184196060992518e-5 1.49298807690802e-5 5295/4893/5290/5335/7305/5291/5336/54209/6850/54210/2534/695/2885/7410/3133/3932/5296/3845/3265/5879 20 Human_respiratory_syncytial_virus_B R-HSA-6784531 tRNA processing in the nucleus 24/1832 57/10654 8.497773472604411e-6 3.162129227411388e-5 1.617663623250417e-5 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 24 Human_respiratory_syncytial_virus_B R-HSA-5696398 Nucleotide Excision Repair 38/1832 111/10654 9.94431955228162e-6 3.690012957461803e-5 1.887715302355056e-5 10450/9318/6118/5430/7336/86/5431/8450/54778/7316/9978/64708/10980/6119/5437/10401/10920/2033/142/10987/7329/6233/2873/2968/7311/60/8533/8607/5983/6117/7334/7874/50813/7314/51138/8451/8554/7528 38 Human_respiratory_syncytial_virus_B R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 23/1832 54/10654 1.0368488647307535e-5 3.8259143863388976e-5 1.957238962532031e-5 10450/9318/5430/5431/8450/7316/9978/64708/10980/5437/10920/2033/10987/6233/2873/2968/7311/8533/7874/50813/7314/51138/8451 23 Human_respiratory_syncytial_virus_B R-HSA-74751 Insulin receptor signalling cascade 23/1832 54/10654 1.0368488647307535e-5 3.8259143863388976e-5 1.957238962532031e-5 5295/54106/5170/3643/4893/5290/3667/5291/5594/2322/57761/5140/2261/3630/208/2885/8660/5296/117145/3845/3265/5781/5595 23 Human_respiratory_syncytial_virus_B R-HSA-198753 ERK/MAPK targets 13/1832 22/10654 1.1719117359467495e-5 4.3002650088490444e-5 2.1999044867772313e-5 1849/5594/5528/5519/5598/1432/5518/6197/5600/51231/5595/5515/5516 13 Human_respiratory_syncytial_virus_B R-HSA-5205685 Pink/Parkin Mediated Mitophagy 13/1832 22/10654 1.1719117359467495e-5 4.3002650088490444e-5 2.1999044867772313e-5 65018/9140/8878/10452/7416/9474/7316/56993/6233/9804/7311/54543/7314 13 Human_respiratory_syncytial_virus_B R-HSA-68882 Mitotic Anaphase 59/1832 201/10654 1.197355667505333e-5 4.381459381646939e-5 2.241441430349683e-5 4000/5905/5684/5903/11065/246184/5525/55869/7321/991/5526/8697/9212/348995/79023/57122/6232/7443/8881/5528/7316/10213/5501/23279/51433/79902/5715/5519/9183/5701/5688/1062/7846/8243/9126/5529/5710/51529/7324/64682/29945/10393/6233/5527/51434/5716/7514/7311/5518/10383/5347/29882/55746/7112/5696/7314/996/5515/5516 59 Human_respiratory_syncytial_virus_B R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 24/1832 58/10654 1.2153558507349435e-5 4.3865712536089086e-5 2.2440565319868675e-5 8454/8841/142678/892/55869/3280/6500/10013/23385/7316/9978/9611/4609/5664/10014/8850/1387/2033/55294/3066/3065/6233/7311/7314 24 Human_respiratory_syncytial_virus_B R-HSA-2644603 Signaling by NOTCH1 in Cancer 24/1832 58/10654 1.2153558507349435e-5 4.3865712536089086e-5 2.2440565319868675e-5 8454/8841/142678/892/55869/3280/6500/10013/23385/7316/9978/9611/4609/5664/10014/8850/1387/2033/55294/3066/3065/6233/7311/7314 24 Human_respiratory_syncytial_virus_B R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 24/1832 58/10654 1.2153558507349435e-5 4.3865712536089086e-5 2.2440565319868675e-5 8454/8841/142678/892/55869/3280/6500/10013/23385/7316/9978/9611/4609/5664/10014/8850/1387/2033/55294/3066/3065/6233/7311/7314 24 Human_respiratory_syncytial_virus_B R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 24/1832 58/10654 1.2153558507349435e-5 4.3865712536089086e-5 2.2440565319868675e-5 8454/8841/142678/892/55869/3280/6500/10013/23385/7316/9978/9611/4609/5664/10014/8850/1387/2033/55294/3066/3065/6233/7311/7314 24 Human_respiratory_syncytial_virus_B R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 24/1832 58/10654 1.2153558507349435e-5 4.3865712536089086e-5 2.2440565319868675e-5 8454/8841/142678/892/55869/3280/6500/10013/23385/7316/9978/9611/4609/5664/10014/8850/1387/2033/55294/3066/3065/6233/7311/7314 24 Human_respiratory_syncytial_virus_B R-HSA-1296041 Activation of G protein gated Potassium channels 14/1832 25/10654 1.2609771032518413e-5 4.4898942140045344e-5 2.296913889311057e-5 2788/54331/3766/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 14 Human_respiratory_syncytial_virus_B R-HSA-1296059 G protein gated Potassium channels 14/1832 25/10654 1.2609771032518413e-5 4.4898942140045344e-5 2.296913889311057e-5 2788/54331/3766/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 14 Human_respiratory_syncytial_virus_B R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 14/1832 25/10654 1.2609771032518413e-5 4.4898942140045344e-5 2.296913889311057e-5 1849/5594/5528/5519/5598/1432/1385/5518/6197/5600/51231/5595/5515/5516 14 Human_respiratory_syncytial_virus_B R-HSA-8854691 Interleukin-20 family signaling 14/1832 25/10654 1.2609771032518413e-5 4.4898942140045344e-5 2.296913889311057e-5 6775/6776/6774/3718/6772/3717/163702/3716/282618/3588/6777/6773/7297/5781 14 Human_respiratory_syncytial_virus_B R-HSA-997272 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits 14/1832 25/10654 1.2609771032518413e-5 4.4898942140045344e-5 2.296913889311057e-5 2788/54331/3766/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 14 Human_respiratory_syncytial_virus_B R-HSA-1980143 Signaling by NOTCH1 28/1832 73/10654 1.3269833072886702e-5 4.712217604646058e-5 2.410648792527805e-5 8454/8841/142678/892/55869/3280/6500/409/3091/10013/23385/7316/9978/9611/4609/5664/10014/8850/1387/2033/408/55294/3066/3065/83737/6233/7311/7314 28 Human_respiratory_syncytial_virus_B R-HSA-2555396 Mitotic Metaphase and Anaphase 59/1832 202/10654 1.413311815794664e-5 5.0053214709510754e-5 2.560593158572525e-5 4000/5905/5684/5903/11065/246184/5525/55869/7321/991/5526/8697/9212/348995/79023/57122/6232/7443/8881/5528/7316/10213/5501/23279/51433/79902/5715/5519/9183/5701/5688/1062/7846/8243/9126/5529/5710/51529/7324/64682/29945/10393/6233/5527/51434/5716/7514/7311/5518/10383/5347/29882/55746/7112/5696/7314/996/5515/5516 59 Human_respiratory_syncytial_virus_B R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 11/1832 17/10654 1.691546532368038e-5 5.9746870835780176e-5 3.0564955636934434e-5 23643/7186/8737/355/841/7099/929/8772/353376/8743/148022 11 Human_respiratory_syncytial_virus_B R-HSA-2467813 Separation of Sister Chromatids 56/1832 190/10654 1.735986048759624e-5 6.115300187763902e-5 3.128429595238396e-5 5905/5684/5903/11065/246184/5525/55869/7321/991/5526/8697/9212/348995/79023/57122/6232/8881/5528/7316/10213/5501/23279/51433/79902/5715/5519/9183/5701/5688/1062/7846/8243/9126/5529/5710/51529/7324/64682/29945/10393/6233/5527/51434/5716/7514/7311/5518/10383/5347/29882/55746/5696/7314/996/5515/5516 56 Human_respiratory_syncytial_virus_B R-HSA-2428928 IRS-related events triggered by IGF1R 22/1832 52/10654 1.8301685219682125e-5 6.429927174255342e-5 3.2893846335486914e-5 5295/54106/5170/4893/5290/3667/5291/2322/57761/5140/2261/8471/208/2885/8660/3479/5296/117145/3845/3265/5781/3480 22 Human_respiratory_syncytial_virus_B R-HSA-195253 Degradation of beta-catenin by the destruction complex 30/1832 82/10654 1.9615968274703622e-5 6.87339365805928e-5 3.5162506302833236e-5 8454/8945/5684/1499/5525/5526/1452/6500/5528/7316/10213/9978/6934/5715/5519/2932/5701/5688/5529/5710/3065/6233/5527/5716/7311/5518/5696/7314/5515/5516 30 Human_respiratory_syncytial_virus_B R-HSA-5654732 Negative regulation of FGFR3 signaling 15/1832 29/10654 2.2115545716616377e-5 7.708347200963123e-5 3.943391292894797e-5 5594/7316/673/6714/2261/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 15 Human_respiratory_syncytial_virus_B R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 15/1832 29/10654 2.2115545716616377e-5 7.708347200963123e-5 3.943391292894797e-5 2308/2309/4303/23410/4287/847/114907/84676/4088/2908/3630/3066/3065/4087/56729 15 Human_respiratory_syncytial_virus_B R-HSA-8949215 Mitochondrial calcium ion transport 13/1832 23/10654 2.271291547763125e-5 7.895726669987073e-5 4.039249788542731e-5 10730/11331/8165/7419/7416/7417/6687/30968/3954/221154/10367/10939/5245 13 Human_respiratory_syncytial_virus_B R-HSA-450341 Activation of the AP-1 family of transcription factors 8/1832 10/10654 2.441562027842951e-5 8.44320271932078e-5 4.319324392050633e-5 3725/5594/1432/2353/1386/5599/5600/5595 8 Human_respiratory_syncytial_virus_B R-HSA-9020958 Interleukin-21 signaling 8/1832 10/10654 2.441562027842951e-5 8.44320271932078e-5 4.319324392050633e-5 3561/6775/6776/6774/3718/6772/3716/6777 8 Human_respiratory_syncytial_virus_B R-HSA-2428924 IGF1R signaling cascade 22/1832 53/10654 2.625264362124589e-5 9.054762982680372e-5 4.6321828239219076e-5 5295/54106/5170/4893/5290/3667/5291/2322/57761/5140/2261/8471/208/2885/8660/3479/5296/117145/3845/3265/5781/3480 22 Human_respiratory_syncytial_virus_B R-HSA-844456 The NLRP3 inflammasome 10/1832 15/10654 2.8623829906977236e-5 9.846895652895033e-5 5.037417434287112e-5 834/351/4790/10910/7295/29108/5970/3326/114548/4791 10 Human_respiratory_syncytial_virus_B R-HSA-1266695 Interleukin-7 signaling 17/1832 36/10654 2.9362017476349928e-5 1.0074603918508637e-4 5.1539071004283395e-5 5295/3667/6597/3561/6776/6774/3718/8651/8503/3716/85480/8660/1154/3575/5296/8835/6777 17 Human_respiratory_syncytial_virus_B R-HSA-5654736 Signaling by FGFR1 21/1832 50/10654 3.2271050803915704e-5 1.1044056505692396e-4 5.649853999485651e-5 5295/4893/5290/5335/5594/10817/7316/673/6714/867/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 21 Human_respiratory_syncytial_virus_B R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 19/1832 43/10654 3.248560721918809e-5 1.1088756366032937e-4 5.672721293273155e-5 2788/54331/59345/10681/359/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 19 Human_respiratory_syncytial_virus_B R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 32/1832 92/10654 3.4127411959156526e-5 1.1619152370630353e-4 5.944058187134696e-5 1017/6118/1459/6874/9212/11200/545/472/580/7316/890/1457/6790/8148/6119/1432/4683/7157/6233/672/7311/5562/6880/5300/5983/6117/5600/5564/1020/7314/4193/1263 32 Human_respiratory_syncytial_virus_B R-HSA-210993 Tie2 Signaling 11/1832 18/10654 3.672794809857872e-5 1.2440415240569868e-4 6.364195055138337e-5 5295/4893/5290/5291/7010/2888/2885/5296/3845/3265/5781 11 Human_respiratory_syncytial_virus_B R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 11/1832 18/10654 3.672794809857872e-5 1.2440415240569868e-4 6.364195055138337e-5 4893/5578/5594/5598/2885/1385/1956/6197/3845/3265/5595 11 Human_respiratory_syncytial_virus_B R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 22/1832 54/10654 3.717300016582867e-5 1.2512625618764858e-4 6.401136019161752e-5 5295/54106/5170/4893/5290/3667/5291/2322/57761/5140/2261/8471/208/2885/8660/3479/5296/117145/3845/3265/5781/3480 22 Human_respiratory_syncytial_virus_B R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 15/1832 30/10654 3.72252980179757e-5 1.2512625618764858e-4 6.401136019161752e-5 6118/7320/8450/7316/9978/6119/7398/57599/6233/7311/5983/6117/7314/51514/8451 15 Human_respiratory_syncytial_virus_B R-HSA-114452 Activation of BH3-only proteins 15/1832 30/10654 3.72252980179757e-5 1.2512625618764858e-4 6.401136019161752e-5 596/10018/7027/572/7532/207/10971/7533/1869/10000/7157/208/7161/5599/7159 15 Human_respiratory_syncytial_virus_B R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 14/1832 27/10654 4.0239607750725795e-5 1.3491503004748419e-4 6.901904401807629e-5 23643/7186/842/8737/355/841/7099/836/929/8772/353376/26060/8743/148022 14 Human_respiratory_syncytial_virus_B R-HSA-449836 Other interleukin signaling 13/1832 24/10654 4.176678903264591e-5 1.393281017982961e-4 7.127665751982636e-5 5803/1436/920/1435/1441/1440/836/163702/6844/3716/282618/3588/7297 13 Human_respiratory_syncytial_virus_B R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 13/1832 24/10654 4.176678903264591e-5 1.393281017982961e-4 7.127665751982636e-5 596/2309/5747/207/5594/1027/10000/208/7514/1385/2353/1956/5595 13 Human_respiratory_syncytial_virus_B R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 30/1832 85/10654 4.339768743946889e-5 1.4440389195853503e-4 7.387330063937168e-5 8454/1017/5684/7027/207/1027/6500/898/7316/10213/1869/5753/993/890/1026/4609/5715/5701/5688/6502/10000/5710/208/6233/5716/55957/51343/7311/5696/7314 30 Human_respiratory_syncytial_virus_B R-HSA-4086398 Ca2+ pathway 24/1832 62/10654 4.541912100638964e-5 1.507503991191978e-4 7.712000974901387e-5 2788/54331/6885/1499/59345/5578/10681/51764/94235/55970/2792/6934/2793/2785/2783/2784/2782/2786/4343/3845/801/2791/2790/2787 24 Human_respiratory_syncytial_virus_B R-HSA-5357786 TNFR1-induced proapoptotic signaling 9/1832 13/10654 4.742510003158083e-5 1.570139276734794e-4 8.032426914727581e-5 7124/7186/8737/7375/841/27005/7128/8772/1540 9 Human_respiratory_syncytial_virus_B R-HSA-187687 Signalling to ERKs 16/1832 34/10654 5.312188278678931e-5 1.754350179033717e-4 8.974802302399667e-5 4893/5594/673/6714/1432/4914/5603/2885/1398/5906/3845/5600/3265/1399/6300/5595 16 Human_respiratory_syncytial_virus_B R-HSA-1234174 Cellular response to hypoxia 27/1832 75/10654 6.968349265067667e-5 2.2955584486669298e-4 1.1743483995730259e-4 5684/112399/7321/7422/3091/7323/7316/10213/9978/7322/5715/5701/5688/1387/2033/5710/25994/7428/8453/6233/2056/5716/7311/2034/54583/5696/7314 27 Human_respiratory_syncytial_virus_B R-HSA-1632852 Macroautophagy 32/1832 95/10654 6.98636997740108e-5 2.2957698358574196e-4 1.1744565397987673e-4 65018/139341/1459/9140/8878/10452/7249/10533/64419/7416/9474/192111/7316/1457/8678/6714/64223/56993/6009/55054/6233/2475/9804/7311/54543/5562/55626/3312/5564/57521/7248/7314 32 Human_respiratory_syncytial_virus_B R-HSA-6806834 Signaling by MET 28/1832 79/10654 7.088194652933272e-5 2.3234504060855714e-4 1.1886172044359829e-4 5295/4893/5290/85440/5770/5747/9101/7316/6774/4233/6714/867/9146/2335/5771/3914/6233/2885/1398/7311/5906/3845/3265/1399/5781/53916/7314/5879 28 Human_respiratory_syncytial_virus_B R-HSA-190236 Signaling by FGFR 30/1832 87/10654 7.138980006507161e-5 2.329739801967282e-4 1.1918346968907088e-4 5295/4893/5290/5335/5430/5594/3178/10817/5431/4686/7316/673/6714/2962/2261/867/5437/7072/6233/2885/7311/5518/3845/3265/5781/5725/7314/5595/5515/5516 30 Human_respiratory_syncytial_virus_B R-HSA-69202 Cyclin E associated events during G1/S transition 29/1832 83/10654 7.142654199823991e-5 2.329739801967282e-4 1.1918346968907088e-4 8454/1017/5684/7027/207/1027/6500/898/7316/10213/1869/5753/993/890/1026/4609/5715/5701/5688/6502/10000/5710/208/6233/5716/55957/7311/5696/7314 29 Human_respiratory_syncytial_virus_B R-HSA-9006115 Signaling by NTRK2 (TRKB) 13/1832 25/10654 7.33535585327838e-5 2.3867007591578176e-4 1.2209744510771896e-4 5295/4893/5290/5335/10817/6714/2534/2885/3845/3265/1020/5781/5879 13 Human_respiratory_syncytial_virus_B R-HSA-6804760 Regulation of TP53 Activity through Methylation 11/1832 19/10654 7.367377643974427e-5 2.3912299429214296e-4 1.223291464485085e-4 11200/472/7316/2033/7157/6233/7311/10419/10919/7314/4193 11 Human_respiratory_syncytial_virus_B R-HSA-4755510 SUMOylation of immune response proteins 8/1832 11/10654 7.594973376630104e-5 2.453046413332119e-4 1.2549151737991317e-4 51588/8517/5970/4792/10401/7329/9641/4791 8 Human_respiratory_syncytial_virus_B R-HSA-9614399 Regulation of localization of FOXO transcription factors 8/1832 11/10654 7.594973376630104e-5 2.453046413332119e-4 1.2549151737991317e-4 2308/2309/7532/207/10971/4303/10000/208 8 Human_respiratory_syncytial_virus_B R-HSA-195721 Signaling by WNT 84/1832 331/10654 8.725211808560297e-5 2.8112206827093054e-4 1.4381478770463955e-4 2788/8454/57154/8945/1173/5684/8295/857/54331/7015/6885/5579/6597/1499/5525/59345/1459/5526/207/1452/5578/5582/6500/10681/409/79577/51764/9101/94235/64750/8452/5528/55366/7316/10213/9978/55970/1457/5216/2792/6934/4609/81847/5715/5519/2932/5701/5688/1387/2793/2033/2785/2783/2784/5529/5710/2782/3065/2786/208/6233/5527/5716/7514/163/7311/5518/1213/387/331/8607/4343/25776/3845/801/2791/5696/7314/5879/4221/2790/5515/2787/5516 84 Human_respiratory_syncytial_virus_B R-HSA-1251985 Nuclear signaling by ERBB4 15/1832 32/10654 9.621191276314899e-5 3.0848528339834906e-4 1.578131016707758e-4 2670/23118/51741/23385/348/6776/9611/10413/6714/2099/5664/3084/6285/11033/6387 15 Human_respiratory_syncytial_virus_B R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 15/1832 32/10654 9.621191276314899e-5 3.0848528339834906e-4 1.578131016707758e-4 5295/5777/4690/5336/930/6850/4067/29760/2534/695/2885/7409/5293/118788/801 15 Human_respiratory_syncytial_virus_B R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 23/1832 61/10654 1.0479108612011403e-4 3.351792367183308e-4 1.7146903858573521e-4 25/3984/71/5747/4690/4771/5594/4644/6850/4641/3320/998/695/2885/1398/7410/10096/3326/7409/23191/60/5879/5595 23 Human_respiratory_syncytial_virus_B R-HSA-5696395 Formation of Incision Complex in GG-NER 18/1832 43/10654 1.2340131920962136e-4 3.937515523572701e-4 2.0143312212707074e-4 6118/7336/8450/54778/7316/9978/6119/10401/142/7329/6233/2968/7311/6117/7334/7314/8451/8554 18 Human_respiratory_syncytial_virus_B R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 33/1832 102/10654 1.3188083579930112e-4 4.197941785322332e-4 2.147558569008277e-4 8454/7124/1147/8945/23495/5684/8744/7186/8600/9039/6500/330/10673/7316/10213/9020/7133/5715/5701/5688/329/23291/5710/9040/6233/5716/7311/7187/958/5696/4791/959/7314 33 Human_respiratory_syncytial_virus_B R-HSA-9034015 Signaling by NTRK3 (TRKC) 10/1832 17/10654 1.3258252310446712e-4 4.2089685583851174e-4 2.1531995812448668e-4 5295/4893/5290/3667/5335/6714/2885/581/3845/3265 10 Human_respiratory_syncytial_virus_B R-HSA-186797 Signaling by PDGF 22/1832 58/10654 1.328644881791517e-4 4.2089685583851174e-4 2.1531995812448668e-4 5295/4893/5290/5335/5291/4690/5921/6778/6776/6774/6772/6714/2885/1398/5155/5296/3845/6777/3265/1399/5781/1291 22 Human_respiratory_syncytial_virus_B R-HSA-112409 RAF-independent MAPK1/3 activation 12/1832 23/10654 1.3401056919376303e-4 4.23511870586031e-4 2.166577321138148e-4 1849/5594/983/3717/3716/1843/3570/7297/5781/3569/3572/5595 12 Human_respiratory_syncytial_virus_B R-HSA-8876384 Listeria monocytogenes entry into host cells 11/1832 20/10654 1.383153695963205e-4 4.36073038751168e-4 2.23083701245667e-4 1499/7316/4233/6714/867/999/9146/6233/2885/7311/7314 11 Human_respiratory_syncytial_virus_B R-HSA-163359 Glucagon signaling in metabolic regulation 15/1832 33/10654 1.4852897629671392e-4 4.660493531780501e-4 2.3841880930738926e-4 2788/54331/59345/51764/94235/55970/2778/2785/2783/2784/2782/2786/2791/2790/2787 15 Human_respiratory_syncytial_virus_B R-HSA-2559585 Oncogene Induced Senescence 15/1832 33/10654 1.4852897629671392e-4 4.660493531780501e-4 2.3841880930738926e-4 1029/7027/5594/7316/1869/6667/1031/7157/6233/7311/4343/2113/7314/5595/4193 15 Human_respiratory_syncytial_virus_B R-HSA-6798695 Neutrophil degranulation 113/1832 480/10654 1.7539695665629476e-4 5.490506628980222e-4 2.808801351293121e-4 10450/10694/3303/23352/1727/2934/80331/5777/3837/23412/4893/5036/29099/9218/4790/83858/960/7305/1938/1915/3107/203068/3684/79888/5594/7520/54472/2919/6727/10549/10533/29108/23385/4318/4257/6280/5788/847/2357/10213/10576/5329/5611/1116/6279/7133/6515/7415/4973/3106/3146/4353/170482/2548/1432/5701/3920/9342/140885/3310/5476/929/55832/3320/2495/4311/3728/820/5478/10075/5328/56729/728/6402/3326/948/5580/684/6709/10857/1520/23191/3685/719/47/5906/81567/10855/9522/10383/387/3687/6036/353376/3608/2720/7097/3304/3312/64114/2040/2547/317/1536/3689/7879/8907/53916/6282/1654/1508/114790/5879 113 Human_respiratory_syncytial_virus_B R-HSA-111885 Opioid Signalling 30/1832 91/10654 1.802252585389232e-4 5.628311265482685e-4 2.879298643324342e-4 2788/54331/59345/5578/5594/5582/10681/51764/94235/5528/55970/2792/5519/2793/2785/2783/2784/2782/2786/5499/5580/1385/5518/801/1020/2791/2790/5515/2787/5516 30 Human_respiratory_syncytial_virus_B R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 27/1832 79/10654 1.9107061056440158e-4 5.952931050839021e-4 3.045365739382965e-4 10450/9318/6118/5430/5431/8450/7316/9978/64708/10980/6119/5437/10920/2033/10987/6233/2873/2968/7311/8533/5983/6117/7874/50813/7314/51138/8451 27 Human_respiratory_syncytial_virus_B R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 8/1832 12/10654 1.9338074042196514e-4 6.010728425821552e-4 3.074933383304065e-4 834/58484/55367/472/843/7157/7161/317 8 Human_respiratory_syncytial_virus_B R-HSA-112399 IRS-mediated signalling 19/1832 48/10654 1.9617214801793544e-4 6.083178580556166e-4 3.1119970108108366e-4 5295/54106/5170/4893/5290/3667/5291/2322/57761/5140/2261/208/2885/8660/5296/117145/3845/3265/5781 19 Human_respiratory_syncytial_virus_B R-HSA-611105 Respiratory electron transport 32/1832 100/10654 2.0809564414801297e-4 6.437806696007615e-4 3.2934155933199633e-4 51300/9377/4722/4723/4702/7388/4719/55863/4704/2109/51295/4729/7386/6389/54205/6341/7385/4728/4725/10131/27089/2108/4726/7384/51204/6834/4698/1340/1327/4697/4720/51079 32 Human_respiratory_syncytial_virus_B R-HSA-6783589 Interleukin-6 family signaling 12/1832 24/10654 2.2625434935488064e-4 6.98322419387377e-4 3.572437095077062e-4 9021/6774/6772/867/3717/3716/3570/5008/7297/5781/3569/3572 12 Human_respiratory_syncytial_virus_B R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 22/1832 60/10654 2.3580572436250713e-4 7.261057386547131e-4 3.714569378989807e-4 8454/1147/8945/5684/9039/6500/7316/10213/9020/5970/5715/5701/5688/23291/5710/9040/6233/5716/7311/5696/4791/7314 22 Human_respiratory_syncytial_virus_B R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 9/1832 15/10654 2.3824800629624192e-4 7.285315192530915e-4 3.726979045862264e-4 6737/29110/7316/51428/22954/3661/6233/7311/7314 9 Human_respiratory_syncytial_virus_B R-HSA-354194 GRB2:SOS provides linkage to MAPK signaling for Integrins 9/1832 15/10654 2.3824800629624192e-4 7.285315192530915e-4 3.726979045862264e-4 5747/6714/2244/2335/3690/2885/2266/5906/2243 9 Human_respiratory_syncytial_virus_B R-HSA-372708 p130Cas linkage to MAPK signaling for integrins 9/1832 15/10654 2.3824800629624192e-4 7.285315192530915e-4 3.726979045862264e-4 5747/6714/2244/2335/3690/1398/2266/5906/2243 9 Human_respiratory_syncytial_virus_B R-HSA-6807004 Negative regulation of MET activity 11/1832 21/10654 2.454596916743537e-4 7.474407739477204e-4 3.823713907920128e-4 5770/9101/7316/4233/867/9146/5771/6233/2885/7311/7314 11 Human_respiratory_syncytial_virus_B R-HSA-69615 G1/S DNA Damage Checkpoints 24/1832 68/10654 2.455634336815372e-4 7.474407739477204e-4 3.823713907920128e-4 1017/5684/1029/1027/898/11200/472/7316/10213/993/890/1026/5715/5701/5688/5710/7157/6233/5716/7311/51230/5696/7314/4193 24 Human_respiratory_syncytial_virus_B R-HSA-1296065 Inwardly rectifying K+ channels 14/1832 31/10654 2.6815246005693733e-4 8.124527516862711e-4 4.156298391032201e-4 2788/54331/3766/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 14 Human_respiratory_syncytial_virus_B R-HSA-5654733 Negative regulation of FGFR4 signaling 14/1832 31/10654 2.6815246005693733e-4 8.124527516862711e-4 4.156298391032201e-4 5594/7316/673/6714/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 14 Human_respiratory_syncytial_virus_B R-HSA-71291 Metabolism of amino acids and derivatives 90/1832 372/10654 3.013276340380011e-4 9.108782713139576e-4 4.6598179224954035e-4 6158/4967/6138/6144/38/6203/5684/9349/1728/29920/6206/6194/6191/1373/6128/51121/6132/6147/6129/3620/5160/6217/3028/6222/1743/6176/6152/6136/51601/6125/1468/6528/1737/6224/6146/6141/6202/6232/6160/6155/10213/6175/6218/10165/6209/6193/6231/6229/6165/6130/5715/6142/6204/5701/5688/6228/23521/7965/8604/5831/5162/6143/5710/6124/6207/6139/6233/7306/5716/7311/6223/25873/1738/3921/6188/6189/6135/6201/9045/6187/2744/6168/6208/6157/6137/5696/6122/6133/593/6230 90 Human_respiratory_syncytial_virus_B R-HSA-8939902 Regulation of RUNX2 expression and activity 25/1832 73/10654 3.144302847823229e-4 9.483159958845859e-4 4.851339649849827e-4 8454/57154/5684/10273/6500/7316/10213/9978/865/11059/6772/2099/5715/2932/5701/5688/6502/2908/55294/5710/6233/5716/7311/5696/7314 25 Human_respiratory_syncytial_virus_B R-HSA-1483191 Synthesis of PC 13/1832 28/10654 3.168258156874004e-4 9.533642426493302e-4 4.8771651761494073e-4 1459/79888/43/1120/56994/10400/5130/1457/1119/1103/9468/162466/10390 13 Human_respiratory_syncytial_virus_B R-HSA-74749 Signal attenuation 7/1832 10/10654 3.2497951286193893e-4 9.71262299752537e-4 4.968727012559295e-4 3643/3667/5594/3630/2885/8660/5595 7 Human_respiratory_syncytial_virus_B R-HSA-8853334 Signaling by FGFR3 fusions in cancer 7/1832 10/10654 3.2497951286193893e-4 9.71262299752537e-4 4.968727012559295e-4 5295/4893/5290/2261/2885/3845/3265 7 Human_respiratory_syncytial_virus_B R-HSA-8877330 RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) 7/1832 10/10654 3.2497951286193893e-4 9.71262299752537e-4 4.968727012559295e-4 865/3558/50943/3458/861/3559/1493 7 Human_respiratory_syncytial_virus_B R-HSA-202733 Cell surface interactions at the vascular wall 40/1832 137/10654 3.277899700937195e-4 9.77450452581949e-4 5.000384003805819e-4 5295/5777/3635/4893/857/5290/5335/960/5291/2817/483/6401/3684/7010/1048/2888/2993/338/6714/4973/4067/140885/54210/682/2335/2534/3690/5478/6402/2885/7525/3685/3932/5296/3687/3845/3265/5781/3689/3676 40 Human_respiratory_syncytial_virus_B R-HSA-5628897 TP53 Regulates Metabolic Genes 28/1832 86/10654 3.685827974702464e-4 0.0010966168366175575 5.610008439447563e-4 9377/7532/207/10971/7249/7295/7533/54205/6341/64223/10000/5728/6009/54541/7157/208/2475/51204/5562/6834/4343/1340/1327/4697/5564/2744/57521/7248 28 Human_respiratory_syncytial_virus_B R-HSA-76009 Platelet Aggregation (Plug Formation) 16/1832 39/10654 3.838669685458588e-4 0.0011395241920204033 5.829511385131669e-4 5170/5770/5747/207/6850/6714/4352/2244/2335/3690/1445/2885/1398/2266/5906/2243 16 Human_respiratory_syncytial_virus_B R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 14/1832 32/10654 4.0188399684099334e-4 0.0011903335422128972 6.089438894782103e-4 892/7027/54778/7316/6667/4609/4088/3065/4087/6233/1025/7311/7314/4221 14 Human_respiratory_syncytial_virus_B R-HSA-400253 Circadian Clock 24/1832 70/10654 4.0361345706210966e-4 0.00119273538986988 6.101726126909144e-4 8454/26224/8945/8841/10135/6500/3091/200186/1408/7316/9611/5501/1387/2908/2033/5499/10498/6233/1385/7311/1386/23411/5500/7314 24 Human_respiratory_syncytial_virus_B R-HSA-69563 p53-Dependent G1 DNA Damage Response 23/1832 66/10654 4.0540362607992134e-4 0.00119273538986988 6.101726126909144e-4 1017/5684/1029/1027/898/11200/472/7316/10213/890/1026/5715/5701/5688/5710/7157/6233/5716/7311/51230/5696/7314/4193 23 Human_respiratory_syncytial_virus_B R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 23/1832 66/10654 4.0540362607992134e-4 0.00119273538986988 6.101726126909144e-4 1017/5684/1029/1027/898/11200/472/7316/10213/890/1026/5715/5701/5688/5710/7157/6233/5716/7311/51230/5696/7314/4193 23 Human_respiratory_syncytial_virus_B R-HSA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 8/1832 13/10654 4.269097650465808e-4 0.001250438580103178 6.396920741274473e-4 7027/5422/1869/5519/5518/23649/5515/5516 8 Human_respiratory_syncytial_virus_B R-HSA-171007 p38MAPK events 8/1832 13/10654 4.269097650465808e-4 0.001250438580103178 6.396920741274473e-4 4893/6714/1432/5603/3845/5600/3265/6300 8 Human_respiratory_syncytial_virus_B R-HSA-163685 Integration of energy metabolism 33/1832 108/10654 4.331253151380264e-4 0.0012658374807463116 6.475697538859173e-4 2788/54331/59345/5578/10681/51764/94235/4082/5528/55970/2778/2792/5519/2793/2785/2783/2784/9495/2782/3630/2786/9370/948/6844/47/5906/5518/31/2791/2790/5515/2787/5516 33 Human_respiratory_syncytial_virus_B R-HSA-110320 Translesion Synthesis by POLH 10/1832 19/10654 4.5098625899747354e-4 0.0013151277000787254 6.727853567477123e-4 6118/7316/7415/6119/25898/6233/7311/5983/6117/7314 10 Human_respiratory_syncytial_virus_B R-HSA-110312 Translesion synthesis by REV1 9/1832 16/10654 4.615829149400441e-4 0.0013313341280257606 6.810761466134413e-4 6118/7316/10459/6119/6233/7311/5983/6117/7314 9 Human_respiratory_syncytial_virus_B R-HSA-1834941 STING mediated induction of host immune responses 9/1832 16/10654 4.615829149400441e-4 0.0013313341280257606 6.810761466134413e-4 6737/29110/7520/6778/5591/51428/3428/3661/2547 9 Human_respiratory_syncytial_virus_B R-HSA-205043 NRIF signals cell death from the nucleus 9/1832 16/10654 4.615829149400441e-4 0.0013313341280257606 6.810761466134413e-4 8878/23385/7316/5664/7189/6233/7311/5599/7314 9 Human_respiratory_syncytial_virus_B R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 9/1832 16/10654 4.615829149400441e-4 0.0013313341280257606 6.810761466134413e-4 5295/5170/5290/5291/6850/4067/2534/2885/5296 9 Human_respiratory_syncytial_virus_B R-HSA-391160 Signal regulatory protein family interactions 9/1832 16/10654 4.615829149400441e-4 0.0013313341280257606 6.810761466134413e-4 5777/7305/5747/653509/6714/140885/2885/2185/5781 9 Human_respiratory_syncytial_virus_B R-HSA-9020591 Interleukin-12 signaling 18/1832 47/10654 4.635181204415531e-4 0.0013340031309439905 6.82441539556191e-4 3592/3593/6775/3595/4478/3313/6175/6647/6950/3717/3458/998/5478/3716/3594/7297/5062/3586 18 Human_respiratory_syncytial_virus_B R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 20/1832 55/10654 5.06847247119162e-4 0.0014555330727052456 7.446131181933684e-4 3303/10294/3337/3305/832/2289/7846/2908/3320/3301/10963/3326/3306/367/10383/3304/3312/55466/2288/10728 20 Human_respiratory_syncytial_virus_B R-HSA-5676590 NIK-->noncanonical NF-kB signaling 21/1832 59/10654 5.168228392702765e-4 0.0014809608908373868 7.576213330551832e-4 8454/1147/8945/5684/9039/6500/7316/10213/9020/5715/5701/5688/23291/5710/9040/6233/5716/7311/5696/4791/7314 21 Human_respiratory_syncytial_virus_B R-HSA-5654726 Negative regulation of FGFR1 signaling 14/1832 33/10654 5.885666435578301e-4 0.001682892935367735 8.609245503853427e-4 5594/7316/673/6714/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 14 Human_respiratory_syncytial_virus_B R-HSA-5693565 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 25/1832 76/10654 6.273160395393008e-4 0.001789815309355111 9.15623274716906e-4 8467/25/51588/51720/11200/472/7336/580/29086/7316/9656/4683/165918/7157/7329/8924/6233/672/7158/7311/23030/5536/5599/7334/7314 25 Human_respiratory_syncytial_virus_B R-HSA-68886 M Phase 93/1832 395/10654 6.397233101604511e-4 0.0018212812343145598 9.3172042904494e-4 10844/4000/23165/5905/5684/5903/11065/55706/7175/5579/9631/246184/5525/1459/55869/7321/991/203068/5526/7532/8697/5578/9212/5594/5861/348995/79023/57122/23636/6232/7443/10762/8881/23511/5528/7316/10213/5501/53371/1457/983/23279/4927/9688/51433/79902/5715/5519/9183/9883/5701/5688/1062/7846/23225/7283/3320/8243/9126/5529/5710/51529/8086/7324/64682/29945/10393/6233/5527/51434/5716/7514/7311/9972/5518/10383/5347/8021/29882/129401/84930/55746/8481/7112/5696/10592/55755/8480/7314/996/5595/5515/5516 93 Human_respiratory_syncytial_virus_B R-HSA-445717 Aquaporin-mediated transport 19/1832 52/10654 6.48502060883645e-4 0.0018383502627195175 9.404525030207819e-4 2788/54331/59345/10681/359/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 19 Human_respiratory_syncytial_virus_B R-HSA-75153 Apoptotic execution phase 19/1832 52/10654 6.48502060883645e-4 0.0018383502627195175 9.404525030207819e-4 4000/2934/3837/2339/1499/5747/10059/841/5339/3146/329/999/836/4137/3836/5580/6709/7431/5062 19 Human_respiratory_syncytial_virus_B R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 21/1832 60/10654 6.681397472975342e-4 0.0018899627541328536 9.668561202862998e-4 8454/1017/5684/1027/6500/898/7316/10213/5753/890/1026/5715/5701/5688/6502/5710/6233/5716/7311/5696/7314 21 Human_respiratory_syncytial_virus_B R-HSA-8856828 Clathrin-mediated endocytosis 41/1832 146/10654 6.705706243269678e-4 0.001892785886187873 9.683003617137053e-4 9318/1173/23396/71/4738/1601/1785/409/1080/29978/338/7316/920/64708/26052/10980/867/9146/10920/408/9829/10987/29979/6233/2885/2873/10096/6844/163/7311/3575/1759/1213/2580/1956/60/8533/3312/50813/7314/51138 41 Human_respiratory_syncytial_virus_B R-HSA-68875 Mitotic Prophase 40/1832 142/10654 7.251678817494152e-4 0.0020425304302579476 0.0010449058020045438 4000/23165/5903/55706/7175/5579/9631/5578/5594/5861/348995/79023/57122/23636/7443/10762/23511/53371/983/23279/4927/9688/79902/5519/9883/23225/8086/9972/5518/5347/8021/129401/84930/55746/7112/10592/8480/5595/5515/5516 40 Human_respiratory_syncytial_virus_B R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 7/1832 11/10654 7.607816262793058e-4 0.002120237401508361 0.0010846586810377846 7422/3091/1387/2033/25994/2056/2034 7 Human_respiratory_syncytial_virus_B R-HSA-196025 Formation of annular gap junctions 7/1832 11/10654 7.607816262793058e-4 0.002120237401508361 0.0010846586810377846 1173/71/1601/1785/1759/1213/60 7 Human_respiratory_syncytial_virus_B R-HSA-5655291 Signaling by FGFR4 in disease 7/1832 11/10654 7.607816262793058e-4 0.002120237401508361 0.0010846586810377846 5295/4893/5290/5335/2885/3845/3265 7 Human_respiratory_syncytial_virus_B R-HSA-8875555 MET activates RAP1 and RAC1 7/1832 11/10654 7.607816262793058e-4 0.002120237401508361 0.0010846586810377846 85440/4233/2885/1398/5906/1399/5879 7 Human_respiratory_syncytial_virus_B R-HSA-8934903 Receptor Mediated Mitophagy 7/1832 11/10654 7.607816262793058e-4 0.002120237401508361 0.0010846586810377846 139341/1459/9140/9474/192111/1457/6714 7 Human_respiratory_syncytial_virus_B R-HSA-167044 Signalling to RAS 10/1832 20/10654 7.636571483986298e-4 0.002123770722178084 0.0010864662366136739 4893/6714/1432/4914/5603/2885/3845/5600/3265/6300 10 Human_respiratory_syncytial_virus_B R-HSA-5693606 DNA Double Strand Break Response 25/1832 77/10654 7.796989476099023e-4 0.002163828381917397 0.0011069587004988 8467/25/51588/51720/11200/472/7336/580/29086/7316/9656/4683/165918/7157/7329/8924/6233/672/7158/7311/23030/5536/5599/7334/7314 25 Human_respiratory_syncytial_virus_B R-HSA-8948751 Regulation of PTEN stability and activity 23/1832 69/10654 8.286411352621347e-4 0.002279433066291372 0.001166099070527958 5684/1459/10273/207/7316/10213/1457/4734/81847/5715/5701/5688/10000/5728/5710/208/6233/5716/7311/331/5696/23608/7314 23 Human_respiratory_syncytial_virus_B R-HSA-177929 Signaling by EGFR 18/1832 49/10654 8.298181893999628e-4 0.002279433066291372 0.001166099070527958 5295/4893/5290/5335/7316/6714/867/9146/1445/998/6233/2885/7311/1956/3845/3265/5781/7314 18 Human_respiratory_syncytial_virus_B R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 18/1832 49/10654 8.298181893999628e-4 0.002279433066291372 0.001166099070527958 1017/7027/7832/1027/4869/898/1869/890/983/1026/6790/2033/995/7157/10498/581/3276/1263 18 Human_respiratory_syncytial_virus_B R-HSA-5655862 Translesion synthesis by POLK 9/1832 17/10654 8.317083557550654e-4 0.002279433066291372 0.001166099070527958 6118/7316/10459/6119/6233/7311/5983/6117/7314 9 Human_respiratory_syncytial_virus_B R-HSA-5656121 Translesion synthesis by POLI 9/1832 17/10654 8.317083557550654e-4 0.002279433066291372 0.001166099070527958 6118/7316/10459/6119/6233/7311/5983/6117/7314 9 Human_respiratory_syncytial_virus_B R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 9/1832 17/10654 8.317083557550654e-4 0.002279433066291372 0.001166099070527958 2308/857/2309/4303/1027/1026/9314/4088/4087 9 Human_respiratory_syncytial_virus_B R-HSA-5654727 Negative regulation of FGFR2 signaling 14/1832 34/10654 8.438680379114417e-4 0.002304690461127775 0.0011790201012343371 5594/7316/673/6714/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 14 Human_respiratory_syncytial_virus_B R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 8/1832 14/10654 8.461581178251104e-4 0.002304690461127775 0.0011790201012343371 4893/5921/5753/1398/387/3845/3265/5879 8 Human_respiratory_syncytial_virus_B R-HSA-8983432 Interleukin-15 signaling 8/1832 14/10654 8.461581178251104e-4 0.002304690461127775 0.0011790201012343371 3561/6776/3560/6774/3718/2885/3716/6777 8 Human_respiratory_syncytial_virus_B R-HSA-5655302 Signaling by FGFR1 in disease 15/1832 38/10654 9.406788982636153e-4 0.002546386935668516 0.0013026657736955156 5295/4893/5290/5335/9530/613/6776/6774/6772/2885/11160/3845/6777/3265/7750 15 Human_respiratory_syncytial_virus_B R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 15/1832 38/10654 9.406788982636153e-4 0.002546386935668516 0.0013026657736955156 3815/7422/4869/51741/2064/348/1026/2099/4609/3329/1387/2033/7329/1956/7528 15 Human_respiratory_syncytial_virus_B R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 15/1832 38/10654 9.406788982636153e-4 0.002546386935668516 0.0013026657736955156 6597/1459/6045/6598/6599/86/865/1457/2033/6605/57332/861/648/6601/23466 15 Human_respiratory_syncytial_virus_B R-HSA-422356 Regulation of insulin secretion 25/1832 78/10654 9.632632389272933e-4 0.002596879058414193 0.0013284962392939256 2788/54331/59345/5578/10681/51764/94235/4082/55970/2778/2792/2793/2785/2783/2784/9495/2782/3630/2786/948/6844/5906/2791/2790/2787 25 Human_respiratory_syncytial_virus_B R-HSA-74752 Signaling by Insulin receptor 25/1832 78/10654 9.632632389272933e-4 0.002596879058414193 0.0013284962392939256 5295/54106/5170/3643/4893/5290/3667/5291/526/5594/2322/57761/5140/2261/529/3630/208/2885/8660/5296/117145/3845/3265/5781/5595 25 Human_respiratory_syncytial_virus_B R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 13/1832 31/10654 0.001049147575646295 0.002819603611940378 0.0014424363670789454 857/1499/5525/5526/1452/5528/5519/2932/5529/5527/5518/5515/5516 13 Human_respiratory_syncytial_virus_B R-HSA-8940973 RUNX2 regulates osteoblast differentiation 11/1832 24/10654 0.0010501475980883165 0.002819603611940378 0.0014424363670789454 25/8841/5594/3280/10013/865/10413/6714/7525/367/5595 11 Human_respiratory_syncytial_virus_B R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 22/1832 66/10654 0.0010660595315023582 0.0028565205702122017 0.0014613221292292388 5684/112399/7321/3091/7323/7316/10213/9978/7322/5715/5701/5688/5710/7428/8453/6233/5716/7311/2034/54583/5696/7314 22 Human_respiratory_syncytial_virus_B R-HSA-8953750 Transcriptional Regulation by E2F6 14/1832 35/10654 0.001186454073627604 0.0031726838689515487 0.0016230631051969353 23468/5888/7027/2146/8317/6045/1869/23512/672/8726/648/317/10919/6241 14 Human_respiratory_syncytial_virus_B R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 15/1832 39/10654 0.001288686354337213 0.003439100351675674 0.0017593548952354932 6118/9636/7706/7316/10459/7415/6119/25898/9246/6233/7311/7318/5983/6117/7314 15 Human_respiratory_syncytial_virus_B R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 12/1832 28/10654 0.0012959539572823902 0.0034515225354234623 0.001765709763529912 10694/10575/5203/7203/10576/908/6950/7846/10574/10383/60/22948 12 Human_respiratory_syncytial_virus_B R-HSA-1226099 Signaling by FGFR in disease 21/1832 63/10654 0.0013724654990934838 0.0036479414975905274 0.0018661926303463233 5295/4893/5290/5335/5430/9530/613/5431/6776/4686/6774/6772/2962/2261/5437/2885/11160/3845/6777/3265/7750 21 Human_respiratory_syncytial_virus_B R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 20/1832 59/10654 0.0014015925084473377 0.0037130519838753187 0.0018995014730849474 7319/7321/9646/7320/79577/7336/5591/7323/7316/8915/7415/7322/118424/7324/6233/7311/7334/7332/3105/7314 20 Human_respiratory_syncytial_virus_B R-HSA-111471 Apoptotic factor-mediated response 9/1832 18/10654 0.0014110159696483044 0.0037130519838753187 0.0018995014730849474 1029/842/5594/54205/836/331/581/317/5595 9 Human_respiratory_syncytial_virus_B R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 9/1832 18/10654 0.0014110159696483044 0.0037130519838753187 0.0018995014730849474 5295/5290/613/6776/6774/6772/2885/6777/7750 9 Human_respiratory_syncytial_virus_B R-HSA-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 9/1832 18/10654 0.0014110159696483044 0.0037130519838753187 0.0018995014730849474 7186/8600/330/10673/9020/329/7187/958/959 9 Human_respiratory_syncytial_virus_B R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 9/1832 18/10654 0.0014110159696483044 0.0037130519838753187 0.0018995014730849474 7027/983/6790/2033/995/7157/10498/581/3276 9 Human_respiratory_syncytial_virus_B R-HSA-8941858 Regulation of RUNX3 expression and activity 19/1832 55/10654 0.0014183497320690598 0.0037249304096684454 0.0019055781688570397 57154/5684/1029/64750/7316/10213/865/6714/5715/5701/5688/2033/5710/6233/5716/7311/5696/7314/4193 19 Human_respiratory_syncytial_virus_B R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 31/1832 106/10654 0.001424289232545618 0.0037331072940332568 0.0019097612516589112 9318/1173/4738/1601/409/1080/29978/338/7316/920/64708/10980/867/9146/10920/408/10987/29979/6233/2885/2873/6844/163/7311/3575/1213/1956/8533/50813/7314/51138 31 Human_respiratory_syncytial_virus_B R-HSA-111447 Activation of BAD and translocation to mitochondria 8/1832 15/10654 0.0015409125310009567 0.004022817101684315 0.002057969304977354 596/572/7532/207/10971/7533/10000/208 8 Human_respiratory_syncytial_virus_B R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 8/1832 15/10654 0.0015409125310009567 0.004022817101684315 0.002057969304977354 7316/4233/867/9146/6233/2885/7311/7314 8 Human_respiratory_syncytial_virus_B R-HSA-190873 Gap junction degradation 7/1832 12/10654 0.0015551428664795817 0.004036038755637578 0.0020647331615756205 1173/71/1601/1785/1759/1213/60 7 Human_respiratory_syncytial_virus_B R-HSA-264870 Caspase-mediated cleavage of cytoskeletal proteins 7/1832 12/10654 0.0015551428664795817 0.004036038755637578 0.0020647331615756205 2934/841/5339/836/4137/6709/7431 7 Human_respiratory_syncytial_virus_B R-HSA-5689877 Josephin domain DUBs 7/1832 12/10654 0.0015551428664795817 0.004036038755637578 0.0020647331615756205 4287/7316/7415/9929/6233/7311/7314 7 Human_respiratory_syncytial_virus_B R-HSA-5687128 MAPK6/MAPK4 signaling 27/1832 89/10654 0.0015600005668861268 0.0040407073506991634 0.0020671214942020503 2308/3725/5684/2309/10642/3315/3337/5596/7316/10213/983/5597/4609/5715/5701/5688/5710/998/6233/5716/7514/7311/4343/5062/5696/7314/5879 27 Human_respiratory_syncytial_virus_B R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 11/1832 25/10654 0.001586597214463944 0.004093544766224355 0.002094151750998873 1017/993/890/983/5519/995/7514/5518/5347/5515/5516 11 Human_respiratory_syncytial_virus_B R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 11/1832 25/10654 0.001586597214463944 0.004093544766224355 0.002094151750998873 3135/3107/10484/6890/821/811/3106/3309/3133/3134/3105 11 Human_respiratory_syncytial_virus_B R-HSA-5619115 Disorders of transmembrane transporters 46/1832 176/10654 0.0017263671121750363 0.004445479444801604 0.0022741924407845967 23165/5684/5903/55706/7175/9631/64241/6528/1080/348995/79023/57122/23636/10762/1244/23511/7316/10213/335/53371/3098/23279/4927/9688/7415/79902/5715/9883/5701/5688/23225/682/5710/8086/6233/5716/7311/9972/11160/8021/129401/213/55746/5696/8480/7314 46 Human_respiratory_syncytial_virus_B R-HSA-165159 mTOR signalling 15/1832 40/10654 0.0017386496679232086 0.004468397298300698 0.0022859166225818145 6194/207/84335/7249/6198/64223/1981/6009/208/2475/5562/1978/5564/57521/7248 15 Human_respiratory_syncytial_virus_B R-HSA-109704 PI3K Cascade 16/1832 44/10654 0.0017994762567611886 0.004615743951808796 0.002361295364007528 5295/54106/5170/5290/3667/5291/2322/57761/5140/2261/208/2885/8660/5296/117145/5781 16 Human_respiratory_syncytial_virus_B R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 19/1832 56/10654 0.0018063535871564267 0.004624405210530309 0.002365726240217107 3303/5684/3184/3315/26986/7316/10213/5715/5701/5688/1981/5710/6233/5716/7311/3304/3312/5696/7314 19 Human_respiratory_syncytial_virus_B R-HSA-1250196 SHC1 events in ERBB2 signaling 10/1832 22/10654 0.001917886237251088 0.004900440463072897 0.00250693874440639 4893/2065/5578/2064/3084/2885/5580/1956/3845/3265 10 Human_rhinovirus_A_serotype_89 R-HSA-5620912 Anchoring of the basal body to the plasma membrane 95/1200 98/10654 2.955441240874785e-87 3.6470144912394845e-84 1.742154836726189e-84 115106/22995/55559/79867/11258/22981/8636/7531/10142/54903/80776/11190/203068/54801/7532/55125/1454/10382/85302/51134/95681/121441/7277/79441/5116/54806/9814/91147/5048/1781/23354/80321/8766/22832/146057/8655/9738/79598/983/1639/55722/4957/10121/9702/5566/79959/132320/347240/84131/7846/7840/7283/3320/22919/27077/22994/11064/4867/79600/10540/84902/10733/1069/4751/117177/5577/80254/57545/26005/54930/5518/26123/10383/55835/54820/5347/23322/9662/80184/55142/23332/1453/22897/9793/4218/5108/261734/8481/57787/93323/10806/51259/55755/9657/1778 95 Human_rhinovirus_A_serotype_89 R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 80/1200 82/10654 3.29713520955284e-74 1.356221616196068e-71 6.478581464384527e-72 114791/10844/115106/22995/55559/440145/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/653784/5048/1781/23354/728642/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/984/80097/10426/22994/11064/10540/10733/85378/1069/4751/5577/27175/80254/54930/5518/10383/55835/54820/5347/29922/9662/80184/55142/23332/1453/22897/27229/9793/5108/8481/93323/10806/55755/1778 80 Human_rhinovirus_A_serotype_89 R-HSA-380287 Centrosome maturation 80/1200 82/10654 3.29713520955284e-74 1.356221616196068e-71 6.478581464384527e-72 114791/10844/115106/22995/55559/440145/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/653784/5048/1781/23354/728642/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/984/80097/10426/22994/11064/10540/10733/85378/1069/4751/5577/27175/80254/54930/5518/10383/55835/54820/5347/29922/9662/80184/55142/23332/1453/22897/27229/9793/5108/8481/93323/10806/55755/1778 80 Human_rhinovirus_A_serotype_89 R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 81/1200 88/10654 3.8433873549041273e-69 1.1856849989879232e-66 5.6639392598587136e-67 8454/115106/8945/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/84962/55125/1454/10382/95681/6500/121441/7277/79441/5116/9814/5048/1781/23354/7316/80321/8655/9738/983/1639/6790/55722/4957/10121/9702/5566/79959/84131/23291/7846/7840/7283/3320/22919/22994/11064/10540/10733/79866/1069/4751/5577/6233/80254/7311/54930/5518/10133/10383/55835/54820/5347/9662/80184/55142/23332/1453/22897/9793/4218/5108/8481/93323/10806/55755/7314/1778 81 Human_rhinovirus_A_serotype_89 R-HSA-8854518 AURKA Activation by TPX2 71/1200 73/10654 1.498178448551626e-65 3.6975044110254135e-63 1.7662735393450748e-63 115106/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/22974/10382/3161/95681/121441/7277/79441/5116/9814/5048/1781/23354/80321/8655/9738/983/1639/6790/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/22994/11064/10540/10733/1069/4751/5577/80254/54930/5518/10383/55835/54820/5347/9662/80184/55142/23332/1453/22897/9793/5108/8481/93323/10806/55755/1778 71 Human_rhinovirus_A_serotype_89 R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 81/1200 94/10654 9.396815369486034e-64 1.932611694324294e-61 9.231958959495052e-62 114791/10844/115106/4926/22995/55559/79861/440145/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/653784/5048/1781/23354/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/347733/3320/22919/80097/10426/22994/11064/10540/10733/85378/1069/4751/5577/27175/80254/54930/5518/10383/55835/54820/5347/29922/9662/80184/55142/23332/1453/22897/27229/9793/5108/8481/93323/10806/55755/1778 81 Human_rhinovirus_A_serotype_89 R-HSA-380259 Loss of Nlp from mitotic centrosomes 68/1200 70/10654 1.1281344524088191e-62 1.7401473928406034e-60 8.31256964932814e-61 115106/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/5048/1781/23354/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/22994/11064/10540/10733/1069/4751/5577/80254/54930/5518/10383/55835/54820/5347/9662/80184/55142/23332/1453/22897/9793/5108/8481/93323/10806/55755/1778 68 Human_rhinovirus_A_serotype_89 R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 68/1200 70/10654 1.1281344524088191e-62 1.7401473928406034e-60 8.31256964932814e-61 115106/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/5048/1781/23354/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/22994/11064/10540/10733/1069/4751/5577/80254/54930/5518/10383/55835/54820/5347/9662/80184/55142/23332/1453/22897/9793/5108/8481/93323/10806/55755/1778 68 Human_rhinovirus_A_serotype_89 R-HSA-69275 G2/M Transition 117/1200 196/10654 1.7300272088259394e-61 2.3720595285457883e-59 1.1331172361900887e-59 114791/10844/8454/115106/1017/8945/22995/55559/5684/79861/440145/2305/11258/22981/8636/7531/51512/10142/11190/5707/203068/54801/7532/84962/63943/55125/1454/22974/10382/3161/95681/6500/121441/7277/79441/5116/9814/653784/5048/1781/23354/7316/728642/80321/8655/9738/983/1026/1639/6790/55722/4957/10121/9702/5566/79959/84131/5688/23291/7846/7840/7283/347733/3320/22919/984/5686/80097/2033/995/10426/5710/22994/11064/10540/7157/10733/85378/79866/1069/4751/5577/6233/3326/27175/80254/5716/7514/7311/54930/5518/10133/10383/55835/54820/5347/29922/9662/80184/55142/23332/1453/22897/7465/27229/9793/4218/5108/1022/8481/5693/93323/10806/55755/7314/5515/1778 117 Human_rhinovirus_A_serotype_89 R-HSA-453274 Mitotic G2-G2/M phases 117/1200 198/10654 8.386437965577437e-61 1.0348864449522557e-58 4.943584484971963e-59 114791/10844/8454/115106/1017/8945/22995/55559/5684/79861/440145/2305/11258/22981/8636/7531/51512/10142/11190/5707/203068/54801/7532/84962/63943/55125/1454/22974/10382/3161/95681/6500/121441/7277/79441/5116/9814/653784/5048/1781/23354/7316/728642/80321/8655/9738/983/1026/1639/6790/55722/4957/10121/9702/5566/79959/84131/5688/23291/7846/7840/7283/347733/3320/22919/984/5686/80097/2033/995/10426/5710/22994/11064/10540/7157/10733/85378/79866/1069/4751/5577/6233/3326/27175/80254/5716/7514/7311/54930/5518/10133/10383/55835/54820/5347/29922/9662/80184/55142/23332/1453/22897/7465/27229/9793/4218/5108/1022/8481/5693/93323/10806/55755/7314/5515/1778 117 Human_rhinovirus_A_serotype_89 R-HSA-5617833 Cilium Assembly 109/1200 201/10654 1.9128959796681403e-51 2.1459214899186228e-49 1.0250925824058932e-49 115106/10694/22995/55559/79867/79861/11258/22981/8636/7531/10142/54903/80776/11190/203068/54801/7532/10575/55125/1454/10382/85302/51134/95681/121441/7277/79441/10013/26146/5116/54806/9814/91147/5048/1781/23354/10576/80321/8766/22832/60412/146057/8655/9738/79598/983/1639/55722/149371/4957/10121/9702/5566/79959/132320/347240/84131/6950/7846/7840/7283/347733/3320/22919/27077/22994/11064/4867/79600/10540/84902/10733/1069/4751/117177/5577/80254/57545/26005/54930/5518/26123/10383/55835/54820/5347/23322/22948/9662/80184/55142/23332/1453/8195/22897/9793/4218/5108/261734/8481/57787/140735/93323/10806/51259/55755/9657/1778/55770 109 Human_rhinovirus_A_serotype_89 R-HSA-68877 Mitotic Prometaphase 106/1200 200/10654 9.676872319658763e-49 9.951050368715761e-47 4.753551314920094e-47 114791/10844/115106/4926/11130/22995/55559/81929/79861/54908/440145/11258/22981/25936/8636/7531/10142/80776/1459/55869/1783/11190/203068/54801/7532/55125/1454/10382/9212/95681/121441/1460/7277/79441/79980/5116/6232/332/1780/9814/653784/5885/5048/1781/23354/80321/8655/9738/1457/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/347733/3320/22919/80097/79003/8243/9126/11243/10426/22994/11064/51143/10540/10733/85378/1069/4751/5577/27175/80254/7514/54930/5518/10383/55835/54820/5347/29922/9662/80184/55142/23332/1453/22897/27229/9793/10726/5108/8481/140735/93323/10806/55755/5515/1778 106 Human_rhinovirus_A_serotype_89 R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 82/1200 129/10654 3.111524391095389e-46 2.953554691239777e-44 1.4108936510230105e-44 8454/23643/1147/3725/11035/8945/1326/351/9252/4790/6885/5606/5604/11213/7321/8737/10392/8767/29110/5594/4214/6500/330/23118/246330/10333/841/7099/8517/4615/7316/79155/7335/5970/4792/7096/9261/4793/3146/7867/7322/64127/5598/1432/329/23291/929/114609/3656/6195/57162/10454/3661/695/3654/7189/5609/6233/10010/51135/6196/7311/5518/7187/1386/8772/9641/6197/5599/353376/7334/7097/3551/5608/57161/4791/51231/7314/5595/5515/148022/257397 82 Human_rhinovirus_A_serotype_89 R-HSA-166166 MyD88-independent TLR4 cascade 70/1200 99/10654 2.327448094829813e-44 1.9147139660133262e-42 9.146462688454002e-43 8454/23643/1147/3725/11035/8945/1326/351/9252/4790/6885/5606/5604/7321/8737/10392/8767/29110/5594/6500/330/23118/841/7099/8517/7316/79155/7335/5970/4792/9261/4793/3146/7867/7322/64127/5598/1432/329/23291/929/3656/6195/10454/3661/3654/7189/5609/6233/10010/6196/7311/5518/7187/1386/8772/9641/6197/5599/353376/7334/3551/5608/4791/51231/7314/5595/5515/148022/257397 70 Human_rhinovirus_A_serotype_89 R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 70/1200 99/10654 2.327448094829813e-44 1.9147139660133262e-42 9.146462688454002e-43 8454/23643/1147/3725/11035/8945/1326/351/9252/4790/6885/5606/5604/7321/8737/10392/8767/29110/5594/6500/330/23118/841/7099/8517/7316/79155/7335/5970/4792/9261/4793/3146/7867/7322/64127/5598/1432/329/23291/929/3656/6195/10454/3661/3654/7189/5609/6233/10010/6196/7311/5518/7187/1386/8772/9641/6197/5599/353376/7334/3551/5608/4791/51231/7314/5595/5515/148022/257397 70 Human_rhinovirus_A_serotype_89 R-HSA-168898 Toll-like Receptor Cascades 88/1200 155/10654 8.450890736704543e-44 6.517749480683378e-42 3.113486060891147e-42 8454/23643/1147/3725/11035/8945/1326/351/9252/4790/6885/5606/5604/11213/7184/7321/8737/10392/8767/29110/5594/6271/4214/6500/330/23118/246330/10333/841/7099/8517/4615/7098/7316/79155/7335/5970/4792/7096/5289/9261/4793/6279/3146/7867/7322/64127/5598/1432/329/23291/929/114609/3656/6195/57162/10454/3661/695/3654/7189/5609/6233/10010/51135/6196/7311/5518/7187/1386/8772/9641/6197/5599/353376/7334/7097/3551/30849/5608/57161/4791/51231/7314/5595/5515/148022/257397 88 Human_rhinovirus_A_serotype_89 R-HSA-1852241 Organelle biogenesis and maintenance 125/1200 296/10654 1.2392452899511111e-43 8.99546286940983e-42 4.297073451223667e-42 115106/10694/5563/22995/55559/79867/79861/11258/22981/8636/7531/10142/54903/80776/11190/203068/54801/7532/10575/55125/1454/10382/85302/51134/95681/51422/121441/7277/79441/10013/26146/53632/5116/3313/54806/5465/9814/91147/5048/1781/23354/10576/80321/8766/22832/60412/146057/8655/9738/79598/983/1639/54205/55722/149371/4957/10121/9702/5566/79959/132320/347240/84131/1432/5571/1387/6950/7846/7840/7283/347733/3320/22919/27077/22994/11064/4867/79600/10540/84902/10733/1069/4751/117177/5577/80254/57545/26005/54930/5518/26123/10383/1386/55835/54820/5347/23322/22948/6742/3054/9662/80184/55142/23332/1453/8195/22897/5564/801/9793/5565/4218/5108/261734/8481/57787/140735/93323/814/10806/51259/55755/9657/1778/55770 125 Human_rhinovirus_A_serotype_89 R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 67/1200 94/10654 7.351264491936983e-43 5.039700212805687e-41 2.4074316464822864e-41 8454/1147/3725/11035/8945/1326/351/9252/4790/6885/5606/5604/7321/8737/10392/8767/29110/5594/6500/330/23118/841/8517/7098/7316/79155/7335/5970/4792/9261/4793/3146/7867/7322/64127/5598/1432/329/23291/3656/6195/10454/3661/3654/7189/5609/6233/10010/6196/7311/5518/7187/1386/8772/9641/6197/5599/7334/3551/5608/4791/51231/7314/5595/5515/148022/257397 67 Human_rhinovirus_A_serotype_89 R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 67/1200 95/10654 2.23071135895298e-42 1.3763489084739888e-40 6.574728215861414e-41 8454/23643/1147/3725/8945/1326/351/9252/4790/6885/5606/5604/11213/10392/8767/5594/4214/6500/23118/246330/10333/7099/8517/4615/7316/79155/7335/5970/4792/7096/9261/4793/3146/7867/64127/5598/1432/23291/929/114609/3656/6195/57162/10454/695/3654/7189/5609/6233/51135/6196/7311/5518/1386/6197/5599/7334/7097/3551/5608/57161/4791/51231/7314/5595/5515/257397 67 Human_rhinovirus_A_serotype_89 R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 67/1200 95/10654 2.23071135895298e-42 1.3763489084739888e-40 6.574728215861414e-41 8454/23643/1147/3725/8945/1326/351/9252/4790/6885/5606/5604/11213/10392/8767/5594/4214/6500/23118/246330/10333/7099/8517/4615/7316/79155/7335/5970/4792/7096/9261/4793/3146/7867/64127/5598/1432/23291/929/114609/3656/6195/57162/10454/695/3654/7189/5609/6233/51135/6196/7311/5518/1386/6197/5599/7334/7097/3551/5608/57161/4791/51231/7314/5595/5515/257397 67 Human_rhinovirus_A_serotype_89 R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 67/1200 98/10654 5.399565179354658e-41 3.028665196056204e-39 1.4467734451859372e-39 8454/23643/1147/3725/8945/1326/351/9252/4790/6885/5606/5604/11213/10392/8767/5594/4214/6500/23118/246330/10333/7099/8517/4615/7316/79155/7335/5970/4792/7096/9261/4793/3146/7867/64127/5598/1432/23291/929/114609/3656/6195/57162/10454/695/3654/7189/5609/6233/51135/6196/7311/5518/1386/6197/5599/7334/7097/3551/5608/57161/4791/51231/7314/5595/5515/257397 67 Human_rhinovirus_A_serotype_89 R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 67/1200 98/10654 5.399565179354658e-41 3.028665196056204e-39 1.4467734451859372e-39 8454/23643/1147/3725/8945/1326/351/9252/4790/6885/5606/5604/11213/10392/8767/5594/4214/6500/23118/246330/10333/7099/8517/4615/7316/79155/7335/5970/4792/7096/9261/4793/3146/7867/64127/5598/1432/23291/929/114609/3656/6195/57162/10454/695/3654/7189/5609/6233/51135/6196/7311/5518/1386/6197/5599/7334/7097/3551/5608/57161/4791/51231/7314/5595/5515/257397 67 Human_rhinovirus_A_serotype_89 R-HSA-2262752 Cellular responses to stress 159/1200 479/10654 1.3316652046856645e-39 7.144673315574391e-38 3.412963453656623e-38 1017/818/3303/7014/6118/3725/815/25913/81929/1019/5684/79861/4790/5241/11258/5606/64344/9448/3159/112399/7531/1029/1915/1783/7321/5707/2146/84962/817/6045/7422/10382/5594/93661/9530/3308/1027/10294/5925/55860/3091/830/7013/7277/10013/50488/545/3337/192670/3576/3313/10808/10671/1780/3490/847/4306/1781/7316/10935/3305/8655/6774/5970/84516/1026/1639/9261/9532/54205/832/6667/2289/10121/7415/6647/7867/4194/7322/6119/5598/1432/2932/10524/5688/1387/7846/3310/2908/3309/347733/3320/5686/2033/1021/7266/6195/6009/5710/6767/51143/3301/816/7428/192669/10540/9531/7157/8453/10963/22824/57600/5609/6233/3326/2475/5716/3306/1030/51343/6196/7311/367/2034/79400/10383/23411/6117/6197/29882/5599/54583/3304/3312/201163/4217/26523/405/5608/96459/3569/3297/57521/5693/10641/55466/140735/2288/5034/10728/829/7314/51164/51182/5595/4193/2950/1778/23043 159 Human_rhinovirus_A_serotype_89 R-HSA-4420097 VEGFA-VEGFR2 Pathway 66/1200 99/10654 2.5274049331152655e-39 1.2995073697767657e-37 6.207661239230477e-38 5295/26999/5170/5590/4893/857/5290/5335/71/558/5579/5291/1499/6461/5747/5567/10006/207/7422/10458/5578/3315/3708/1793/9261/10152/6714/7867/5566/8936/1432/10163/10810/10000/3320/55845/5063/2534/9475/3690/4846/3728/208/1398/5580/2475/23191/6093/3685/9844/2185/3791/387/9564/3845/3265/5058/801/3071/8877/5062/63916/5829/10787/5879/253260 66 Human_rhinovirus_A_serotype_89 R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 65/1200 97/10654 5.906997430041568e-39 2.9156939314685177e-37 1.3928078150834854e-37 8454/23643/1147/3725/8945/1326/351/9252/4790/6885/5606/5604/10392/8767/5594/4214/6500/23118/246330/7099/8517/4615/7316/79155/7335/5970/4792/5289/9261/4793/3146/7867/64127/5598/1432/23291/929/3656/6195/57162/10454/3654/7189/5609/6233/51135/6196/7311/5518/1386/6197/5599/353376/7334/3551/30849/5608/57161/4791/51231/7314/5595/5515/148022/257397 65 Human_rhinovirus_A_serotype_89 R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 63/1200 92/10654 1.1441233933675083e-38 5.4301856439057895e-37 2.59396396876844e-37 8454/23643/1147/3725/8945/1326/351/9252/4790/6885/5606/5604/10392/8767/5594/4214/6500/23118/246330/7099/8517/4615/7316/79155/7335/5970/4792/9261/4793/3146/7867/64127/5598/1432/23291/929/3656/6195/57162/10454/3654/7189/5609/6233/51135/6196/7311/5518/1386/6197/5599/353376/7334/3551/5608/57161/4791/51231/7314/5595/5515/148022/257397 63 Human_rhinovirus_A_serotype_89 R-HSA-194138 Signaling by VEGF 68/1200 107/10654 1.8284760938454825e-38 8.356812962241946e-37 3.991994590851735e-37 5295/26999/5170/5590/4893/857/5290/5335/71/558/5579/5291/1499/6461/5747/5567/10006/207/7422/10458/5578/3315/3708/8829/1793/9261/10152/6714/7867/5566/8936/1432/10163/10810/10000/3320/55845/5063/2534/9475/3690/4846/3728/208/1398/5580/2324/2475/23191/6093/3685/9844/2185/3791/387/9564/3845/3265/5058/801/3071/8877/5062/63916/5829/10787/5879/253260 68 Human_rhinovirus_A_serotype_89 R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 63/1200 93/10654 3.17128736208298e-38 1.3494374499346197e-36 6.44617394833564e-37 8454/23643/1147/3725/8945/1326/351/9252/4790/6885/5606/5604/10392/8767/5594/4214/6500/23118/246330/7099/8517/4615/7316/79155/7335/5970/4792/9261/4793/3146/7867/64127/5598/1432/23291/929/3656/6195/57162/10454/3654/7189/5609/6233/51135/6196/7311/5518/1386/6197/5599/353376/7334/3551/5608/57161/4791/51231/7314/5595/5515/148022/257397 63 Human_rhinovirus_A_serotype_89 R-HSA-975155 MyD88 dependent cascade initiated on endosome 63/1200 93/10654 3.17128736208298e-38 1.3494374499346197e-36 6.44617394833564e-37 8454/23643/1147/3725/8945/1326/351/9252/4790/6885/5606/5604/10392/8767/5594/4214/6500/23118/246330/7099/8517/4615/7316/79155/7335/5970/4792/9261/4793/3146/7867/64127/5598/1432/23291/929/3656/6195/57162/10454/3654/7189/5609/6233/51135/6196/7311/5518/1386/6197/5599/353376/7334/3551/5608/57161/4791/51231/7314/5595/5515/148022/257397 63 Human_rhinovirus_A_serotype_89 R-HSA-8953897 Cellular responses to external stimuli 159/1200 493/10654 7.585589388913327e-38 3.120205768639682e-36 1.4905017746636712e-36 1017/818/3303/7014/6118/3725/815/25913/81929/1019/5684/79861/4790/5241/11258/5606/64344/9448/3159/112399/7531/1029/1915/1783/7321/5707/2146/84962/817/6045/7422/10382/5594/93661/9530/3308/1027/10294/5925/55860/3091/830/7013/7277/10013/50488/545/3337/192670/3576/3313/10808/10671/1780/3490/847/4306/1781/7316/10935/3305/8655/6774/5970/84516/1026/1639/9261/9532/54205/832/6667/2289/10121/7415/6647/7867/4194/7322/6119/5598/1432/2932/10524/5688/1387/7846/3310/2908/3309/347733/3320/5686/2033/1021/7266/6195/6009/5710/6767/51143/3301/816/7428/192669/10540/9531/7157/8453/10963/22824/57600/5609/6233/3326/2475/5716/3306/1030/51343/6196/7311/367/2034/79400/10383/23411/6117/6197/29882/5599/54583/3304/3312/201163/4217/26523/405/5608/96459/3569/3297/57521/5693/10641/55466/140735/2288/5034/10728/829/7314/51164/51182/5595/4193/2950/1778/23043 159 Human_rhinovirus_A_serotype_89 R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 155/1200 473/10654 8.084278759940249e-38 3.2180645128278284e-36 1.537248253163511e-36 5295/26999/5170/5434/5590/1839/9252/4893/8065/6464/685/857/5290/3667/5335/71/558/5241/5579/4915/5291/5604/1499/2065/6461/5747/5567/10006/10273/207/7422/10458/5578/5594/10193/2069/2322/3315/2241/3178/23118/3708/2064/6778/2260/8829/9306/1793/7316/673/1950/5753/6774/11059/5289/4233/9261/4734/10413/10152/6714/2099/10818/7867/3910/5566/8936/5598/1432/2261/867/10163/5159/4670/4067/3717/4914/10810/10000/145957/3320/3084/55845/2335/5063/2534/9475/3690/4846/6195/3728/4803/8471/1111/2264/3630/2066/83737/208/4145/6654/9542/6233/2885/7525/1398/10718/5580/2324/2475/8660/23191/6093/3685/9844/6196/7311/3932/5518/2185/1213/3791/387/1956/8851/5581/9564/6197/3845/2549/3265/5058/801/3071/1020/30849/8877/5062/3480/4486/11140/51231/4916/7529/5156/63916/5829/10787/7314/5879/253260/5595/5515/2242/5607 155 Human_rhinovirus_A_serotype_89 R-HSA-9006925 Intracellular signaling by second messengers 118/1200 305/10654 1.1626224757540432e-36 4.483362922126529e-35 2.1416729816521846e-35 5295/1147/2308/818/5170/27161/3725/815/1839/5684/685/5290/3667/5335/2309/5291/5468/2065/1822/1459/842/572/5707/5567/2146/817/10273/207/6045/5578/5594/2069/4303/1027/7249/5582/1460/3708/2064/6199/192670/2260/4615/2100/7316/1950/1457/4233/8658/1026/4734/10645/6714/2099/10818/5566/84254/10014/2932/2261/5688/5159/3164/10000/145957/3084/5686/2534/5728/6009/2444/5710/6615/2264/816/3630/192669/3066/7157/1107/2066/8975/5613/5987/3654/7189/208/9542/5577/6233/2885/10718/5580/2475/5716/51135/8660/7311/3932/2931/5518/1386/1956/5581/331/2549/26523/801/57521/5693/814/5156/7314/5879/253260/5595/4193/5515 118 Human_rhinovirus_A_serotype_89 R-HSA-5663202 Diseases of signal transduction 132/1200 377/10654 1.4164068687768152e-35 5.231708078384109e-34 2.499152541068925e-34 5295/8454/4000/1147/2308/27044/818/5170/815/5434/7276/1839/5684/4893/6464/685/5290/3667/5335/71/2309/5291/5604/1499/2065/2648/10018/10142/55869/842/572/5707/283455/8844/817/207/1452/5594/3280/2069/9530/4303/613/1027/7249/6500/10533/10013/2064/6199/2260/2100/7316/673/1950/8315/6774/4233/9759/8658/1026/6714/2099/4609/10818/7415/10014/22938/5037/2932/2261/867/5688/1387/5159/7046/3717/3164/10000/145957/3320/3084/5686/2335/2534/2033/3690/408/55294/5728/5710/11064/2264/816/3066/4296/2066/5894/4087/208/6654/9542/6233/2885/10718/2475/5716/8660/7048/7311/51009/3932/2931/5518/1956/4140/3845/2549/3265/369/801/5693/11140/5245/7529/5156/7314/5879/253260/5595/4193/5515 132 Human_rhinovirus_A_serotype_89 R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 58/1200 85/10654 1.5262681590099508e-35 5.231708078384109e-34 2.499152541068925e-34 8454/1147/3725/8945/1326/351/9252/4790/6885/5606/5604/10392/8767/5594/4214/6500/23118/246330/8517/4615/7316/79155/7335/5970/4792/9261/4793/3146/7867/64127/5598/1432/23291/3656/6195/57162/10454/3654/7189/5609/6233/51135/6196/7311/5518/1386/6197/5599/7334/3551/5608/57161/4791/51231/7314/5595/5515/257397 58 Human_rhinovirus_A_serotype_89 R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 58/1200 85/10654 1.5262681590099508e-35 5.231708078384109e-34 2.499152541068925e-34 8454/1147/3725/8945/1326/351/9252/4790/6885/5606/5604/10392/8767/5594/4214/6500/23118/246330/8517/4615/7316/79155/7335/5970/4792/9261/4793/3146/7867/64127/5598/1432/23291/3656/6195/57162/10454/3654/7189/5609/6233/51135/6196/7311/5518/1386/6197/5599/7334/3551/5608/57161/4791/51231/7314/5595/5515/257397 58 Human_rhinovirus_A_serotype_89 R-HSA-975871 MyD88 cascade initiated on plasma membrane 58/1200 85/10654 1.5262681590099508e-35 5.231708078384109e-34 2.499152541068925e-34 8454/1147/3725/8945/1326/351/9252/4790/6885/5606/5604/10392/8767/5594/4214/6500/23118/246330/8517/4615/7316/79155/7335/5970/4792/9261/4793/3146/7867/64127/5598/1432/23291/3656/6195/57162/10454/3654/7189/5609/6233/51135/6196/7311/5518/1386/6197/5599/7334/3551/5608/57161/4791/51231/7314/5595/5515/257397 58 Human_rhinovirus_A_serotype_89 R-HSA-1227986 Signaling by ERBB2 43/1200 50/10654 3.844111955185239e-34 1.2820632845131311e-32 6.124331991191277e-33 5295/1839/4893/8065/6464/685/5290/5335/2065/10273/207/5578/10193/2069/2064/7316/1950/5753/6714/10000/145957/3320/3084/2534/2066/208/4145/6654/9542/6233/2885/7525/10718/5580/7311/387/1956/5581/3845/2549/3265/11140/7314 43 Human_rhinovirus_A_serotype_89 R-HSA-449147 Signaling by Interleukins 144/1200 461/10654 1.6528697008306153e-32 5.3674768705920504e-31 2.564008400180456e-31 5295/8454/7124/1147/2308/3725/7291/8945/1326/596/5684/351/9252/1072/6464/5290/1437/3667/4790/6885/5606/2309/5291/5604/4215/9049/11213/7412/7184/5707/10392/8767/356/207/5292/7422/29110/2625/1439/5594/8878/4582/821/6500/3091/23118/246330/8517/1438/6778/3576/4615/7534/3313/332/1436/4313/7316/6175/79155/6774/920/7335/5970/4792/3055/1026/9261/4793/4609/3146/6647/7867/5566/64127/7132/5598/1432/867/5688/6950/3558/4067/3717/23291/598/836/3320/5686/4843/2335/2534/84867/3656/595/6195/57162/5710/3458/10454/7157/3654/7189/5609/6654/6233/2885/7525/1398/3716/5716/51135/8660/604/6196/7311/3932/5518/2185/1386/5896/6197/8835/5599/4282/7334/3312/3551/6773/7297/5608/3569/57161/5062/4170/5693/4791/5034/51231/829/7314/5595/5515/257397 144 Human_rhinovirus_A_serotype_89 R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 44/1200 55/10654 3.1999907319874917e-32 1.0125098880186064e-30 4.83669314416463e-31 3303/79861/5241/11258/1783/10382/93661/10294/55860/830/7277/3337/10671/1780/4306/1781/3305/8655/84516/1639/832/2289/10121/7846/2908/347733/3320/51143/3301/10540/10963/3326/3306/367/10383/3304/3312/55466/140735/2288/10728/829/51164/1778 44 Human_rhinovirus_A_serotype_89 R-HSA-1632852 Macroautophagy 57/1200 95/10654 1.819767492605526e-30 5.613982714688048e-29 2.681762620681828e-29 5563/64422/7405/65018/1459/79065/9140/11337/22863/8878/60673/9821/10452/51422/7249/1460/10533/53632/84938/115201/26100/9474/7316/83734/11152/8655/5289/1457/440738/8678/6714/8408/5571/84971/6009/9776/55054/81631/55062/6233/2475/9804/7311/23710/84557/5562/11345/55626/3312/5564/23192/5565/30849/57521/7248/140735/7314 57 Human_rhinovirus_A_serotype_89 R-HSA-1257604 PIP3 activates AKT signaling 100/1200 264/10654 3.0702959855035476e-30 9.240842063686287e-29 4.4142894785160113e-29 5295/1147/2308/5170/27161/3725/1839/5684/685/5290/3667/2309/5291/5468/2065/1822/1459/842/572/5707/2146/10273/207/6045/5594/2069/4303/1027/7249/1460/2064/6199/192670/2260/4615/2100/7316/1950/1457/4233/8658/1026/4734/6714/2099/10818/10014/2932/2261/5688/5159/3164/10000/145957/3084/5686/2534/5728/6009/2444/5710/6615/2264/3630/192669/3066/7157/1107/2066/8975/5987/3654/7189/208/9542/6233/2885/10718/2475/5716/51135/8660/7311/3932/2931/5518/1386/1956/331/2549/26523/57521/5693/5156/7314/5879/253260/5595/4193/5515 100 Human_rhinovirus_A_serotype_89 R-HSA-9612973 Autophagy 64/1200 119/10654 3.2681682521485054e-30 9.60218957893156e-29 4.5869028100329895e-29 5563/64422/7405/65018/1459/1915/79065/9140/11337/22863/8878/60673/9821/10452/51422/7249/1080/1460/10533/10013/53632/84938/5116/115201/26100/9474/7316/83734/11152/8655/5289/1457/440738/8678/6714/8408/5571/3920/3320/84971/6009/9776/55054/81631/55062/6233/3326/2475/9804/7311/23710/84557/5562/11345/55626/3312/5564/23192/5565/30849/57521/7248/140735/7314 64 Human_rhinovirus_A_serotype_89 R-HSA-68886 M Phase 127/1200 395/10654 4.8951805864284024e-30 1.4048029868959648e-28 6.710651477111152e-29 114791/10844/4000/115106/4926/11130/22995/55559/81929/5684/79861/54908/440145/11258/5579/22981/25936/8636/7531/10142/80776/1459/55869/1783/11190/7321/5707/91754/203068/54801/7532/55125/1454/5578/10382/9212/5594/95681/5925/121441/1460/7277/79441/79980/5116/6232/332/1780/9814/653784/5885/5048/1781/23354/7316/80321/8655/9738/1457/983/1639/55722/4957/10121/9702/5566/79959/84131/5688/7846/7840/7283/347733/3320/22919/5686/80097/79003/8243/9126/11243/10426/5710/22994/11064/51143/10540/10733/85378/1069/4751/5577/6233/27175/80254/5716/7514/7311/54930/5518/10383/55835/54820/5347/29922/29882/9662/80184/55142/23332/1453/22897/27229/9793/10726/5108/8481/7112/5693/140735/93323/10806/55755/7314/5595/5515/1778 127 Human_rhinovirus_A_serotype_89 R-HSA-450294 MAP kinase activation 46/1200 64/10654 5.1971918540953e-30 1.4575760790803638e-28 6.962745067687483e-29 8454/1147/3725/8945/1326/9252/4790/6885/5606/5604/10392/8767/5594/6500/23118/8517/7316/79155/7335/9261/7867/64127/5598/1432/23291/3656/6195/10454/3654/7189/5609/6233/6196/7311/5518/1386/6197/5599/7334/3551/5608/51231/7314/5595/5515/257397 46 Human_rhinovirus_A_serotype_89 R-HSA-5357801 Programmed Cell Death 78/1200 181/10654 3.8351869980470085e-28 1.0516935012422241e-26 5.023870687500175e-27 23643/4000/11035/596/5684/7186/1612/51765/1499/10018/7531/5747/1029/842/572/5707/8737/356/7532/207/5594/355/330/2810/841/7099/7534/7316/8655/7082/6774/54205/660/8797/3146/23604/5688/10134/329/999/5588/598/836/929/10000/5686/8837/4137/5710/7157/8626/197259/208/6233/5580/6709/5716/6093/1613/7311/7161/8772/331/5599/353376/8717/7159/317/8743/8795/5062/5693/140735/7529/7314/578/5595/148022 78 Human_rhinovirus_A_serotype_89 R-HSA-5683057 MAPK family signaling cascades 103/1200 294/10654 7.463219059117474e-28 2.002089634554557e-26 9.563850510539553e-27 2308/818/27161/3725/815/1839/5684/4893/6464/685/1437/3667/71/2309/5604/2065/5747/5707/283455/5567/8844/817/1439/5594/2069/2322/3315/2064/3337/1438/192670/2260/5596/8452/7316/673/1950/8315/4233/983/5597/84078/6714/4609/10818/5566/5037/2261/5688/5159/3558/3717/145957/3084/5686/2335/5063/2534/3690/408/5710/2264/816/192669/4296/2066/5894/5979/6654/9542/6233/2885/10718/6709/3716/5716/8660/7514/7311/5518/1956/5536/5896/4140/1843/3845/3265/26523/5058/369/801/7297/8202/3569/5062/5693/5245/7529/5156/7314/5879/5595/5515 103 Human_rhinovirus_A_serotype_89 R-HSA-8848021 Signaling by PTK6 40/1200 54/10654 4.353024396738664e-27 1.119090021994898e-25 5.345819434591341e-26 120892/1017/1839/1019/4893/685/2065/207/2069/55620/1027/3091/2064/1793/7316/1950/5753/6774/867/2908/145957/3084/595/2066/9542/6233/1398/10718/9844/7311/2034/387/1956/9564/3845/3265/63916/5829/7314/5879 40 Human_rhinovirus_A_serotype_89 R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 40/1200 54/10654 4.353024396738664e-27 1.119090021994898e-25 5.345819434591341e-26 120892/1017/1839/1019/4893/685/2065/207/2069/55620/1027/3091/2064/1793/7316/1950/5753/6774/867/2908/145957/3084/595/2066/9542/6233/1398/10718/9844/7311/2034/387/1956/9564/3845/3265/63916/5829/7314/5879 40 Human_rhinovirus_A_serotype_89 R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 29/1200 30/10654 6.237873819823275e-27 1.5709257742167187e-25 7.504209106554315e-26 7124/1147/81858/7186/56957/6885/8737/55072/7375/330/23118/27005/8517/7316/7128/7132/329/9099/10616/10454/6233/7311/331/8717/1540/3551/7185/7314/257397 29 Human_rhinovirus_A_serotype_89 R-HSA-448424 Interleukin-17 signaling 46/1200 72/10654 1.6166840540693806e-26 3.9605689140241022e-25 1.8919377223010298e-25 8454/1147/3725/8945/1326/9252/4790/6885/5606/5604/10392/8767/5594/6500/23118/8517/7316/79155/7335/9261/7867/64127/5598/1432/23291/3656/6195/10454/3654/7189/5609/6233/6196/7311/5518/1386/6197/5599/7334/3551/5608/51231/7314/5595/5515/257397 46 Human_rhinovirus_A_serotype_89 R-HSA-73887 Death Receptor Signalling 66/1200 141/10654 1.6368639758122304e-26 3.9605689140241022e-25 1.8919377223010298e-25 7124/1147/4804/57142/81858/7186/56957/4790/6885/5584/10018/7531/572/8737/8767/55072/356/4974/7375/9530/8878/355/330/23118/841/27005/8517/4615/7316/5970/4792/65078/4168/8797/7128/7132/329/84894/9099/843/836/10616/396/8837/4803/10454/3066/3654/7189/6654/4099/6233/7311/387/8772/331/5599/8717/1540/3551/7185/8743/8795/7314/5879/257397 66 Human_rhinovirus_A_serotype_89 R-HSA-109581 Apoptosis 75/1200 178/10654 2.4486034127929861e-26 5.810724252666433e-25 2.7757447594414416e-25 23643/4000/596/5684/7186/1612/51765/1499/10018/7531/5747/1029/842/572/5707/8737/356/7532/207/5594/355/2810/841/7099/7534/7316/8655/7082/6774/54205/660/8797/3146/23604/5688/10134/329/999/5588/598/836/929/10000/5686/8837/4137/5710/7157/8626/208/6233/5580/6709/5716/6093/1613/7311/7161/8772/331/5599/353376/8717/7159/317/8743/8795/5062/5693/140735/7529/7314/578/5595/148022 75 Human_rhinovirus_A_serotype_89 R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 39/1200 55/10654 2.910971056847009e-25 6.777619404055112e-24 3.237624214169464e-24 1147/596/351/4790/6885/842/10392/8767/10910/330/23118/29108/841/8517/7316/7335/5970/64127/7128/1432/329/598/3656/10454/83737/3654/7189/6233/3326/4210/7311/114548/7334/1540/3551/5608/4791/7314/257397 39 Human_rhinovirus_A_serotype_89 R-HSA-2219528 PI3K/AKT Signaling in Cancer 53/1200 101/10654 1.5663413086643966e-24 3.579379953503454e-23 1.7098462628695165e-23 5295/1147/2308/5170/1839/685/5290/3667/2309/5291/2065/842/572/207/2069/4303/1027/7249/2064/6199/2260/2100/1950/4233/1026/6714/2099/10818/2932/2261/5159/3164/10000/145957/3084/2534/5728/2264/2066/208/9542/2885/10718/2475/8660/3932/2931/1956/2549/5156/5879/253260/4193 53 Human_rhinovirus_A_serotype_89 R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 61/1200 134/10654 8.782392425570627e-24 1.9704495005734826e-22 9.412707671424977e-23 5295/8454/1147/5170/3725/8945/5684/4893/6464/5290/5335/4790/6885/5291/7321/5707/84433/5594/4214/6500/23118/10892/3708/8517/7316/7335/5970/4792/8915/7322/5688/4067/23291/5588/5686/2534/5710/10454/695/7189/5609/6654/6233/2885/5716/3702/7311/3845/5599/7334/3265/3551/5058/801/5062/5693/997/7314/5879/5595/257397 61 Human_rhinovirus_A_serotype_89 R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 45/1200 78/10654 2.663097074979947e-23 5.868324625937954e-22 2.8032600789262594e-22 1147/351/7186/4790/7321/8737/9140/29110/57506/4214/9636/54476/841/7706/8517/84166/9474/7316/5970/4792/4793/3146/23586/7322/7128/1387/843/2033/64135/83737/3661/7189/51191/6233/10010/7311/84282/79671/7187/8772/9641/1540/3551/4791/7314 45 Human_rhinovirus_A_serotype_89 R-HSA-75893 TNF signaling 32/1200 43/10654 5.173273273972109e-22 1.119968284224839e-20 5.350014835502088e-21 7124/1147/81858/7186/56957/6885/8737/55072/7375/9530/330/23118/841/27005/8517/7316/7128/7132/329/9099/10616/10454/6233/7311/8772/331/8717/1540/3551/7185/7314/257397 32 Human_rhinovirus_A_serotype_89 R-HSA-9607240 FLT3 Signaling 88/1200 267/10654 7.899724264079739e-22 1.6807344382542064e-20 8.028757872748919e-21 5295/818/5170/815/1839/5684/4893/6464/685/5290/1437/3667/71/5291/5604/2065/5747/5707/283455/8844/817/1439/5594/2069/2322/2064/1438/2260/8452/7316/673/1950/8315/5289/4233/3055/84078/6714/10818/5037/2261/5688/5159/3558/3717/145957/3084/5686/2335/2534/3690/408/5710/2264/816/4296/2066/5894/5979/208/6654/9542/6233/2885/10718/6709/3716/5716/8660/7311/5518/1956/5536/4140/1843/3845/2549/3265/369/801/30849/5693/5245/7529/5156/7314/5595/5515 88 Human_rhinovirus_A_serotype_89 R-HSA-983169 Class I MHC mediated antigen processing & presentation 108/1200 371/10654 9.814652623274556e-22 2.0527595486645426e-20 9.805897357776541e-21 8454/23643/1147/8773/26224/8945/5684/6737/8065/64410/127544/9666/55070/84708/54850/7319/7321/5707/10273/9817/10193/821/6500/811/10533/144699/26259/51130/10333/7099/8517/4615/8452/54778/7316/7317/7335/7096/84861/11059/4734/84078/7337/26272/222235/7322/23327/55905/5688/10134/55336/26270/6502/23291/10616/929/3309/5686/55521/114609/9903/55294/26190/55008/79654/5710/135892/7428/22954/8453/83737/9040/695/90933/10075/79176/80176/8139/51191/126433/6233/9870/26267/5716/3685/25793/51343/7311/26091/6047/51666/90293/54461/29882/127247/7334/7097/4591/3551/26268/115290/90678/51725/140459/5693/997/51676/7314 108 Human_rhinovirus_A_serotype_89 R-HSA-5621481 C-type lectin receptors (CLRs) 60/1200 142/10654 2.2934418861143066e-21 4.7168454791084236e-20 2.2532060635508974e-20 8454/1147/5170/8945/5684/9252/4893/4790/6885/7321/5707/5567/84433/4582/6500/3384/23118/10892/29108/3708/841/8517/7316/9020/7335/5970/4792/8915/6714/5566/7322/5688/1387/4067/23291/5686/5063/2534/2033/5710/10454/9040/5894/7189/6233/5580/5716/7311/3845/7334/3265/3551/5058/801/5062/5693/997/4791/7314/257397 60 Human_rhinovirus_A_serotype_89 R-HSA-9020702 Interleukin-1 signaling 49/1200 103/10654 2.271777487098901e-20 4.595694129639416e-19 2.195332860699542e-19 8454/1147/8945/1326/5684/351/4790/6885/5604/4215/11213/5707/10392/8767/8878/6500/23118/246330/8517/4615/7316/79155/7335/5970/4792/4793/3146/64127/5688/23291/5686/3656/57162/5710/10454/3654/7189/6233/5716/51135/7311/7334/3551/5608/57161/5693/4791/7314/257397 49 Human_rhinovirus_A_serotype_89 R-HSA-8863795 Downregulation of ERBB2 signaling 25/1200 29/10654 2.372018586138836e-20 4.721082153702134e-19 2.2552298951404895e-19 1839/8065/685/2065/10273/207/10193/2069/2064/7316/1950/10000/145957/3320/3084/2066/208/4145/9542/6233/10718/7311/1956/11140/7314 25 Human_rhinovirus_A_serotype_89 R-HSA-168638 NOD1/2 Signaling Pathway 28/1200 36/10654 2.594296580742134e-20 5.081526953390148e-19 2.427412005372757e-19 1147/6885/842/10392/8767/330/23118/841/8517/7316/7335/64127/7128/1432/329/3656/10454/83737/3654/7189/6233/7311/7334/1540/3551/5608/7314/257397 28 Human_rhinovirus_A_serotype_89 R-HSA-3371556 Cellular response to heat stress 45/1200 89/10654 3.6689032951501503e-20 7.074104165961384e-19 3.3792530350067173e-19 818/3303/6118/815/81929/7531/1915/817/5594/9530/3308/10013/545/3337/3313/10808/3305/9261/9532/7415/6119/2932/1387/3310/3309/3320/2033/7266/6767/816/9531/22824/3326/2475/3306/23411/6117/3304/3312/3297/57521/2288/10728/51182/5595 45 Human_rhinovirus_A_serotype_89 R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 44/1200 86/10654 5.266268953277999e-20 9.997809058992387e-19 4.775887633741991e-19 5295/26999/25/1072/3984/5290/5335/71/5291/5747/10006/4627/10458/4771/5594/2268/3708/1793/3055/10152/6714/8936/10163/4067/10810/3320/55845/2534/695/8976/2885/7525/1398/3326/5580/23191/9844/5581/5058/3071/63916/10787/5879/5595 44 Human_rhinovirus_A_serotype_89 R-HSA-202424 Downstream TCR signaling 47/1200 98/10654 8.958629544666724e-20 1.6749922512301116e-18 8.001327822987823e-19 5295/8454/1147/5170/8945/5684/5290/4790/6885/5291/7321/5707/8767/84433/6500/3123/23118/10892/8517/3126/3115/7316/3122/920/7335/5970/4792/8915/7322/5688/23291/5588/5686/5728/5710/7189/6233/5716/7311/3932/3127/3125/7334/3551/5693/997/7314 47 Human_rhinovirus_A_serotype_89 R-HSA-5213460 RIPK1-mediated regulated necrosis 20/1200 20/10654 9.375232664532196e-20 1.7013289864754016e-18 8.127136675136269e-19 11035/7186/8737/356/355/330/841/7316/8797/329/8837/197259/6233/7311/8772/331/8717/8743/8795/7314 20 Human_rhinovirus_A_serotype_89 R-HSA-5218859 Regulated Necrosis 20/1200 20/10654 9.375232664532196e-20 1.7013289864754016e-18 8.127136675136269e-19 11035/7186/8737/356/355/330/841/7316/8797/329/8837/197259/6233/7311/8772/331/8717/8743/8795/7314 20 Human_rhinovirus_A_serotype_89 R-HSA-5684996 MAPK1/MAPK3 signaling 82/1200 255/10654 1.1942380869432867e-19 2.1357823178087185e-18 1.0202491665724494e-18 818/815/1839/5684/4893/6464/685/1437/3667/71/5604/2065/5747/5707/283455/8844/817/1439/5594/2069/2322/2064/1438/2260/8452/7316/673/1950/8315/4233/983/84078/6714/10818/5037/2261/5688/5159/3558/3717/145957/3084/5686/2335/2534/3690/408/5710/2264/816/4296/2066/5894/5979/6654/9542/6233/2885/10718/6709/3716/5716/8660/7311/5518/1956/5536/4140/1843/3845/3265/369/801/7297/3569/5693/5245/7529/5156/7314/5595/5515 82 Human_rhinovirus_A_serotype_89 R-HSA-202403 TCR signaling 52/1200 119/10654 1.812461043549539e-19 3.1951098967716158e-18 1.5262829840417169e-18 5295/8454/1147/5170/8945/5684/5290/5335/4790/6885/5291/7321/5707/8767/84433/6500/3123/23118/10892/8517/3126/3115/7316/3122/920/7335/5970/4792/8915/7322/5688/23291/5588/5686/5063/5728/5710/7189/6233/5716/3702/7311/3932/3127/3125/7334/3551/5058/5062/5693/997/7314 52 Human_rhinovirus_A_serotype_89 R-HSA-1250196 SHC1 events in ERBB2 signaling 21/1200 22/10654 2.0464670635723346e-19 3.556817403448255e-18 1.6990682810978612e-18 1839/4893/6464/685/2065/5578/2069/2064/1950/145957/3084/2066/6654/9542/2885/10718/5580/1956/5581/3845/3265 21 Human_rhinovirus_A_serotype_89 R-HSA-450302 activated TAK1 mediates p38 MAPK activation 22/1200 24/10654 2.5446941633652906e-19 4.3613230522121784e-18 2.083375338427723e-18 6885/5606/10392/8767/23118/8517/7316/7335/9261/7867/64127/1432/3656/10454/3654/7189/6233/7311/7334/5608/7314/257397 22 Human_rhinovirus_A_serotype_89 R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 26/1200 33/10654 3.3650692768947944e-19 5.611480388767806e-18 2.6805672760470624e-18 1147/351/4790/6885/10392/8767/23118/8517/7316/7335/5970/4792/4793/3146/64127/3656/10454/3654/7189/6233/7311/7334/3551/4791/7314/257397 26 Human_rhinovirus_A_serotype_89 R-HSA-5357905 Regulation of TNFR1 signaling 26/1200 33/10654 3.3650692768947944e-19 5.611480388767806e-18 2.6805672760470624e-18 7124/1147/81858/7186/56957/8737/55072/7375/330/841/27005/8517/7316/7128/7132/329/9099/10616/6233/7311/331/8717/1540/3551/7185/7314 26 Human_rhinovirus_A_serotype_89 R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 19/1200 19/10654 8.442472429068591e-19 1.3707909180882422e-17 6.548178061327438e-18 5295/4893/6464/5290/5335/7316/1950/867/3320/6654/6233/2885/7311/1956/3845/2549/3265/11140/7314 19 Human_rhinovirus_A_serotype_89 R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 19/1200 19/10654 8.442472429068591e-19 1.3707909180882422e-17 6.548178061327438e-18 5295/4893/6464/5290/5335/7316/1950/867/3320/6654/6233/2885/7311/1956/3845/2549/3265/11140/7314 19 Human_rhinovirus_A_serotype_89 R-HSA-3700989 Transcriptional Regulation by TP53 101/1200 365/10654 1.2348189934366196e-18 1.9789177115594657e-17 9.453159758366465e-18 1017/6118/2176/5170/27161/5563/3725/5434/8621/5883/7531/1029/1459/6446/8445/7532/207/22974/9212/1027/4869/51422/7249/355/2810/1460/545/53632/192670/7534/332/639/7316/1457/983/1026/54205/6790/641/8797/4194/112858/6119/3364/1432/5571/10524/1387/56950/9099/843/10000/6794/2033/995/1874/10128/5728/6009/1111/192669/3066/7157/1107/8626/208/6233/2475/672/1025/604/7311/7161/5562/5518/1386/55835/10419/8851/6117/7159/57472/6829/26523/5564/317/5565/1020/5608/5810/10397/1022/8795/665/57521/7248/7529/7314/253260/4193/5515 101 Human_rhinovirus_A_serotype_89 R-HSA-5673001 RAF/MAP kinase cascade 79/1200 249/10654 1.4150535102571751e-18 2.2308512887440552e-17 1.0656629887372438e-17 818/815/1839/5684/4893/6464/685/1437/3667/71/5604/2065/5747/5707/283455/8844/817/1439/5594/2069/2322/2064/1438/2260/8452/7316/673/1950/8315/4233/84078/6714/10818/5037/2261/5688/5159/3558/3717/145957/3084/5686/2335/2534/3690/408/5710/2264/816/4296/2066/5894/5979/6654/9542/6233/2885/10718/6709/3716/5716/8660/7311/5518/1956/5536/4140/1843/3845/3265/369/801/5693/5245/7529/5156/7314/5595/5515 79 Human_rhinovirus_A_serotype_89 R-HSA-8951664 Neddylation 76/1200 234/10654 1.4281787018701812e-18 2.2308512887440552e-17 1.0656629887372438e-17 8454/26224/54165/8945/5684/8065/64410/149951/23038/64344/54850/55884/7321/5707/4738/9817/6500/3091/144699/26259/51130/332/8452/8450/9306/7316/84861/84078/26272/222235/10980/7322/5688/55336/26270/6502/7347/23291/90864/55832/1642/5686/9903/55294/26190/5710/10987/7428/8453/9040/79176/80176/8139/126433/6233/26267/5716/25793/7311/51666/2034/90293/8533/54461/8835/127247/26268/115290/51725/140459/5693/51676/50813/7314/51138/8451 76 Human_rhinovirus_A_serotype_89 R-HSA-1643713 Signaling by EGFR in Cancer 22/1200 25/10654 1.895900008466566e-18 2.9244257630596785e-17 1.396978953606943e-17 5295/1839/4893/6464/685/5290/5335/2069/7316/1950/867/3320/6654/6233/2885/7311/1956/3845/2549/3265/11140/7314 22 Human_rhinovirus_A_serotype_89 R-HSA-5633007 Regulation of TP53 Activity 60/1200 160/10654 2.699226179346352e-18 4.112154451004195e-17 1.9643491363664158e-17 1017/6118/5170/5563/5883/1029/1459/6446/8445/207/22974/9212/51422/1460/545/53632/639/7316/1457/983/6790/641/4194/112858/6119/3364/1432/5571/10524/56950/9099/10000/6794/2033/1111/3066/7157/1107/8626/208/6233/2475/672/7311/7161/5562/5518/10419/8851/6117/7159/5564/5565/1020/5608/5810/7314/253260/4193/5515 60 Human_rhinovirus_A_serotype_89 R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 90/1200 309/10654 2.849420839240618e-18 4.288030872710881e-17 2.0483641463090448e-17 8454/26224/8945/5684/6737/8065/64410/127544/9666/55070/84708/54850/7319/7321/5707/10273/9817/10193/6500/10533/144699/26259/51130/8452/54778/7316/7317/7335/84861/11059/4734/84078/7337/26272/222235/7322/23327/55905/5688/55336/26270/6502/23291/10616/5686/55521/9903/55294/26190/55008/79654/5710/135892/7428/22954/8453/83737/9040/90933/10075/79176/80176/8139/51191/126433/6233/9870/26267/5716/25793/51343/7311/26091/6047/51666/90293/54461/29882/127247/7334/4591/26268/115290/90678/51725/140459/5693/997/51676/7314 90 Human_rhinovirus_A_serotype_89 R-HSA-5675482 Regulation of necroptotic cell death 18/1200 18/10654 7.596796679828568e-18 1.1294514581817412e-16 5.395315333803421e-17 7186/8737/356/355/330/841/7316/8797/329/8837/6233/7311/8772/331/8717/8743/8795/7314 18 Human_rhinovirus_A_serotype_89 R-HSA-438064 Post NMDA receptor activation events 40/1200 81/10654 1.3553344731608544e-17 1.991050880810112e-16 9.511119109900733e-17 818/5170/5563/815/4893/79861/5567/817/10382/5594/51422/7277/53632/10645/6714/5566/84254/5571/27330/7846/347733/3084/6195/4137/816/2066/5613/5577/6196/5562/10383/6197/3845/3265/5564/801/5565/814/5879/5595 40 Human_rhinovirus_A_serotype_89 R-HSA-195258 RHO GTPase Effectors 92/1200 327/10654 1.4396163835415422e-17 2.0899842556356036e-16 9.983717334777258e-17 26999/5170/11130/25/81929/5590/1072/3984/79861/54908/71/5579/1499/25936/7531/5747/80776/1783/10006/4627/2316/7532/10458/4771/5578/10382/9212/5594/3985/1027/1080/2810/7277/79980/6232/7534/332/1780/5048/1781/8655/5289/5585/10152/6279/6714/8936/1432/10163/7846/999/10810/347733/22919/55845/5063/9475/995/3895/79003/11243/51143/695/8976/2885/5580/23191/7514/6093/57120/367/5518/10383/54820/5347/387/23332/5058/801/3071/9793/10726/30849/5586/5062/140735/7529/10787/5879/5595/5515/1778 92 Human_rhinovirus_A_serotype_89 R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 25/1200 34/10654 2.987467002440865e-17 4.2866677686186365e-16 2.0477130004490626e-16 7321/9140/29110/57506/9636/54476/7706/84166/9474/7316/23586/7322/7128/64135/83737/3661/51191/6233/7311/84282/79671/7187/9641/1540/7314 25 Human_rhinovirus_A_serotype_89 R-HSA-937041 IKK complex recruitment mediated by RIP1 21/1200 25/10654 8.413275606349751e-17 1.1933312756592635e-15 5.700465020636249e-16 23643/1147/11035/7321/8737/330/7099/8517/7316/7335/7322/329/929/7189/6233/7311/353376/7334/3551/7314/148022 21 Human_rhinovirus_A_serotype_89 R-HSA-5689896 Ovarian tumor domain proteases 26/1200 38/10654 1.215879507744793e-16 1.704994673360312e-15 8.144647420300048e-16 56957/7321/8737/10392/8767/57506/7706/8517/7316/79155/983/2099/7415/23586/64127/7128/64135/5728/7157/7189/6233/7311/84282/7187/387/7314 26 Human_rhinovirus_A_serotype_89 R-HSA-166520 Signaling by NTRKs 44/1200 101/10654 1.3083015210111985e-16 1.793826752142021e-15 8.568992418318962e-16 5295/9252/4893/6464/5290/3667/5335/4915/5291/5604/5594/673/6774/9261/6714/10818/7867/5598/1432/4914/2534/6195/4803/6654/2885/1398/8660/6196/5518/1213/387/8851/6197/3845/2549/3265/1020/51231/4916/7529/5879/5595/5515/5607 44 Human_rhinovirus_A_serotype_89 R-HSA-5607764 CLEC7A (Dectin-1) signaling 44/1200 101/10654 1.3083015210111985e-16 1.793826752142021e-15 8.568992418318962e-16 8454/1147/5170/8945/5684/4790/6885/7321/5707/84433/6500/23118/10892/29108/3708/841/8517/7316/9020/7335/5970/4792/8915/6714/7322/5688/23291/5686/5710/10454/9040/7189/6233/5580/5716/7311/7334/3551/801/5693/997/4791/7314/257397 44 Human_rhinovirus_A_serotype_89 R-HSA-446652 Interleukin-1 family signaling 53/1200 140/10654 1.6302040063356707e-16 2.210628289910129e-15 1.0560025951971954e-15 8454/1147/8945/1326/5684/351/4790/6885/5604/4215/11213/5707/10392/8767/29110/8878/6500/23118/246330/8517/4615/7316/79155/6774/7335/5970/4792/4793/3146/64127/5688/23291/5686/84867/3656/57162/5710/10454/3654/7189/6233/5716/51135/7311/5599/7334/3551/5608/57161/5693/4791/7314/257397 53 Human_rhinovirus_A_serotype_89 R-HSA-5688426 Deubiquitination 84/1200 297/10654 2.8036380771751556e-16 3.760531942645806e-15 1.7963813766797333e-15 23032/5684/7186/56957/6885/51651/2648/7321/5707/8737/10392/8767/4738/7375/2625/9817/57506/4303/10445/91833/1080/330/3091/11274/4287/27005/7706/8517/7316/79155/7417/4792/9738/8658/983/8678/2099/9100/4609/7415/4194/23586/64127/7128/4798/5688/9097/329/7046/6502/7347/9099/5686/2033/408/64135/5728/5710/10454/7157/10869/8975/4087/7189/6233/5716/672/7048/9804/7311/84282/367/114548/7187/387/23770/8607/7345/3054/1540/5693/5886/7314/4193 84 Human_rhinovirus_A_serotype_89 R-HSA-187037 Signaling by NTRK1 (TRKA) 38/1200 80/10654 4.635812420746883e-16 6.1511747604318864e-15 2.9383757279210575e-15 5295/9252/4893/6464/5290/3667/5335/4915/5291/5604/5594/673/6774/9261/6714/10818/7867/5598/1432/4914/6195/4803/6654/2885/1398/8660/6196/5518/1213/387/6197/3845/3265/51231/7529/5595/5515/5607 38 Human_rhinovirus_A_serotype_89 R-HSA-193639 p75NTR signals via NF-kB 16/1200 16/10654 6.137241334174824e-16 7.807583305537868e-15 3.729631196025938e-15 4804/4790/5584/8767/8878/4615/7316/5970/4792/4803/3654/7189/6233/7311/3551/7314 16 Human_rhinovirus_A_serotype_89 R-HSA-1963640 GRB2 events in ERBB2 signaling 16/1200 16/10654 6.137241334174824e-16 7.807583305537868e-15 3.729631196025938e-15 1839/4893/685/2069/2064/1950/145957/3084/2066/6654/9542/2885/10718/1956/3845/3265 16 Human_rhinovirus_A_serotype_89 R-HSA-1963642 PI3K events in ERBB2 signaling 16/1200 16/10654 6.137241334174824e-16 7.807583305537868e-15 3.729631196025938e-15 5295/1839/685/5290/2065/2069/2064/1950/145957/3084/2066/9542/2885/10718/1956/2549 16 Human_rhinovirus_A_serotype_89 R-HSA-399954 Sema3A PAK dependent Axon repulsion 16/1200 16/10654 6.137241334174824e-16 7.807583305537868e-15 3.729631196025938e-15 1072/3984/5361/10371/8829/55558/3320/5063/2534/91584/3326/5362/5058/5062/5879/2242 16 Human_rhinovirus_A_serotype_89 R-HSA-5260271 Diseases of Immune System 20/1200 24/10654 6.373498436608228e-16 7.944340475529853e-15 3.794959196704528e-15 23643/1147/4790/10333/7099/8517/4615/7098/5970/4792/7096/929/114609/695/51135/7187/7097/3551/4791/148022 20 Human_rhinovirus_A_serotype_89 R-HSA-5602358 Diseases associated with the TLR signaling cascade 20/1200 24/10654 6.373498436608228e-16 7.944340475529853e-15 3.794959196704528e-15 23643/1147/4790/10333/7099/8517/4615/7098/5970/4792/7096/929/114609/695/51135/7187/7097/3551/4791/148022 20 Human_rhinovirus_A_serotype_89 R-HSA-9009391 Extra-nuclear estrogen signaling 37/1200 77/10654 7.039850212047761e-16 8.687175161666937e-15 4.149806440786048e-15 5295/5170/596/5590/1839/4893/6464/685/857/5290/2309/5747/207/5594/2069/1027/3315/2100/4313/1950/6714/2099/10000/3320/4846/595/2771/208/7514/1956/3845/858/3265/801/8877/3480/5595 37 Human_rhinovirus_A_serotype_89 R-HSA-199418 Negative regulation of the PI3K/AKT network 45/1200 110/10654 1.0651638586840213e-15 1.3013982194218636e-14 6.21669370362743e-15 5295/1839/685/5290/3667/5291/2065/207/5594/2069/2064/2260/4615/2100/1950/4233/6714/2099/10818/2261/5159/10000/145957/3084/2534/5728/2264/3630/2066/3654/7189/208/9542/2885/10718/51135/8660/3932/5518/1956/2549/5156/5879/5595/5515 45 Human_rhinovirus_A_serotype_89 R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 18/1200 20/10654 1.1554940095773108e-15 1.3979211841356878e-14 6.67777755792873e-15 1147/11035/7321/8737/330/8517/7098/7316/7335/7322/329/7189/6233/7311/7334/3551/7314/148022 18 Human_rhinovirus_A_serotype_89 R-HSA-109606 Intrinsic Pathway for Apoptosis 30/1200 53/10654 1.1986565137871659e-15 1.4360603281683133e-14 6.8599657406317104e-15 596/10018/7531/1029/842/572/7532/207/5594/2810/841/7534/8655/6774/54205/598/836/10000/7157/8626/208/7161/331/5599/7159/317/140735/7529/578/5595 30 Human_rhinovirus_A_serotype_89 R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 21/1200 27/10654 1.5742884748384847e-15 1.8679538249525868e-14 8.923092569934731e-15 23643/7186/1612/842/8737/356/355/841/7099/8797/23604/836/929/8837/1613/8772/353376/8717/8743/8795/148022 21 Human_rhinovirus_A_serotype_89 R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 28/1200 47/10654 1.7341806370496446e-15 1.9814619501104274e-14 9.46531341859455e-15 818/815/4893/71/5604/283455/8844/817/5594/673/8315/6714/5037/3717/2335/3690/408/816/4296/5894/4140/3845/3265/369/801/5245/7529/5595 28 Human_rhinovirus_A_serotype_89 R-HSA-6802949 Signaling by RAS mutants 28/1200 47/10654 1.7341806370496446e-15 1.9814619501104274e-14 9.46531341859455e-15 818/815/4893/71/5604/283455/8844/817/5594/673/8315/6714/5037/3717/2335/3690/408/816/4296/5894/4140/3845/3265/369/801/5245/7529/5595 28 Human_rhinovirus_A_serotype_89 R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 28/1200 47/10654 1.7341806370496446e-15 1.9814619501104274e-14 9.46531341859455e-15 818/815/4893/71/5604/283455/8844/817/5594/673/8315/6714/5037/3717/2335/3690/408/816/4296/5894/4140/3845/3265/369/801/5245/7529/5595 28 Human_rhinovirus_A_serotype_89 R-HSA-9649948 Signaling downstream of RAS mutants 28/1200 47/10654 1.7341806370496446e-15 1.9814619501104274e-14 9.46531341859455e-15 818/815/4893/71/5604/283455/8844/817/5594/673/8315/6714/5037/3717/2335/3690/408/816/4296/5894/4140/3845/3265/369/801/5245/7529/5595 28 Human_rhinovirus_A_serotype_89 R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 20/1200 25/10654 2.850218194050092e-15 3.226760781153957e-14 1.5414024033491562e-14 1147/2308/5170/2309/842/572/207/4303/1027/7249/6199/1026/2932/3164/10000/208/2475/2931/253260/4193 20 Human_rhinovirus_A_serotype_89 R-HSA-1236394 Signaling by ERBB4 31/1200 58/10654 3.539200061989557e-15 3.9703389786319214e-14 1.8966048179082793e-14 5295/1839/4893/6464/685/5290/5241/2065/2069/23118/7316/1950/11059/4734/10413/6714/2099/145957/3084/2066/83737/6654/9542/6233/2885/10718/7311/1956/3845/3265/7314 31 Human_rhinovirus_A_serotype_89 R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 19/1200 23/10654 4.786868359861458e-15 5.321617618080215e-14 2.5421017368633632e-14 6885/10392/8767/23118/8517/7316/7335/64127/3656/10454/3654/7189/5609/6233/7311/5599/7334/7314/257397 19 Human_rhinovirus_A_serotype_89 R-HSA-442755 Activation of NMDA receptors and postsynaptic events 40/1200 93/10654 5.466479491716298e-15 5.964389105336373e-14 2.8491494489365934e-14 818/5170/5563/815/4893/79861/5567/817/10382/5594/51422/7277/53632/10645/6714/5566/84254/5571/27330/7846/347733/3084/6195/4137/816/2066/5613/5577/6196/5562/10383/6197/3845/3265/5564/801/5565/814/5879/5595 40 Human_rhinovirus_A_serotype_89 R-HSA-5637810 Constitutive Signaling by EGFRvIII 15/1200 15/10654 5.510051523568448e-15 5.964389105336373e-14 2.8491494489365934e-14 5295/4893/6464/5290/5335/1950/867/3320/6654/2885/1956/3845/2549/3265/11140 15 Human_rhinovirus_A_serotype_89 R-HSA-5637812 Signaling by EGFRvIII in Cancer 15/1200 15/10654 5.510051523568448e-15 5.964389105336373e-14 2.8491494489365934e-14 5295/4893/6464/5290/5335/1950/867/3320/6654/2885/1956/3845/2549/3265/11140 15 Human_rhinovirus_A_serotype_89 R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 18/1200 21/10654 7.23728995046298e-15 7.765926781627233e-14 3.7097321485210695e-14 1147/11035/4790/8737/29110/23220/147945/8517/4615/7098/5970/4792/4793/3661/81030/3551/4791/148022 18 Human_rhinovirus_A_serotype_89 R-HSA-2871837 FCERI mediated NF-kB activation 37/1200 82/10654 8.945984139491542e-15 9.516676231148761e-14 4.546053646202599e-14 8454/1147/5170/8945/5684/4790/6885/7321/5707/84433/6500/23118/10892/8517/7316/7335/5970/4792/8915/7322/5688/4067/23291/5588/5686/5710/10454/7189/6233/5716/7311/7334/3551/5693/997/7314/257397 37 Human_rhinovirus_A_serotype_89 R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 16/1200 17/10654 9.34039900813663e-15 9.851326817128719e-14 4.705914030190295e-14 23643/7186/8737/356/355/841/7099/8797/929/8837/8772/353376/8717/8743/8795/148022 16 Human_rhinovirus_A_serotype_89 R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 42/1200 103/10654 1.1091134916819213e-14 1.159869532826687e-13 5.54062047584189e-14 5295/1839/685/5290/3667/5291/2065/207/5594/2069/2064/2260/4615/2100/1950/4233/6714/2099/10818/2261/5159/145957/3084/2534/2264/3630/2066/3654/7189/9542/2885/10718/51135/8660/3932/5518/1956/2549/5156/5879/5595/5515 42 Human_rhinovirus_A_serotype_89 R-HSA-3371571 HSF1-dependent transactivation 19/1200 24/10654 2.0555038721423626e-14 2.131505695986282e-13 1.018206252454421e-13 818/3303/815/817/3337/3305/1387/3320/2033/816/3326/2475/3306/3304/3312/3297/57521/2288/10728 19 Human_rhinovirus_A_serotype_89 R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 31/1200 61/10654 2.2379832642685308e-14 2.3013927900894725e-13 1.0993601999915589e-13 26999/25/1072/3984/71/5747/10006/4627/10458/4771/5594/1793/10152/8936/10163/10810/3320/55845/695/8976/2885/1398/3326/23191/9844/5058/3071/63916/10787/5879/5595 31 Human_rhinovirus_A_serotype_89 R-HSA-69231 Cyclin D associated events in G1 26/1200 44/10654 2.3565680330227773e-14 2.383610617008285e-13 1.1386351151792536e-13 8454/25/894/1019/1029/1027/6500/5925/7316/5753/1026/6714/4067/3717/6502/1021/1874/595/6233/1030/7311/5518/1163/1022/7314/5515 26 Human_rhinovirus_A_serotype_89 R-HSA-69236 G1 Phase 26/1200 44/10654 2.3565680330227773e-14 2.383610617008285e-13 1.1386351151792536e-13 8454/25/894/1019/1029/1027/6500/5925/7316/5753/1026/6714/4067/3717/6502/1021/1874/595/6233/1030/7311/5518/1163/1022/7314/5515 26 Human_rhinovirus_A_serotype_89 R-HSA-5673000 RAF activation 22/1200 32/10654 2.4292054018238198e-14 2.437105256789101e-13 1.1641891527782106e-13 818/815/4893/5604/8844/817/673/8315/6714/3717/816/4296/5894/5518/4140/3845/3265/369/801/5245/7529/5515 22 Human_rhinovirus_A_serotype_89 R-HSA-8939211 ESR-mediated signaling 66/1200 223/10654 4.562023277261488e-14 4.53994897108119e-13 2.1687037650818616e-13 5295/5170/27161/3725/596/5434/5590/1839/4893/6464/685/857/5290/7090/5241/2309/5747/8204/207/2625/5594/2069/1027/3315/5481/192670/5885/2100/4313/1950/6667/2289/6714/2099/4609/10524/1387/10000/3320/2033/8243/4846/9126/595/192669/2066/2771/208/3326/7514/1025/1386/1956/5536/3169/3845/858/3265/26523/801/8202/8877/3480/2288/10728/5595 66 Human_rhinovirus_A_serotype_89 R-HSA-1250347 SHC1 events in ERBB4 signaling 14/1200 14/10654 4.943250270722439e-14 4.879976667257192e-13 2.3311327592459504e-13 1839/4893/6464/685/2069/145957/3084/2066/6654/9542/2885/10718/3845/3265 14 Human_rhinovirus_A_serotype_89 R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 31/1200 63/10654 7.035395739247462e-14 6.890220906532832e-13 3.2914132113438417e-13 1147/11035/5434/6737/4790/1499/8737/29110/81844/23220/147945/8517/6778/4615/7098/5591/7316/5970/4792/4793/1387/2033/22954/3661/6233/7311/81030/3551/4791/7314/148022 31 Human_rhinovirus_A_serotype_89 R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 15/1200 16/10654 7.895496237583228e-14 7.61175184154508e-13 3.636083793623855e-13 8454/1147/8945/1326/4790/5604/6500/8517/7316/79155/23291/6233/7311/3551/7314 15 Human_rhinovirus_A_serotype_89 R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 15/1200 16/10654 7.895496237583228e-14 7.61175184154508e-13 3.636083793623855e-13 23643/6885/23118/7099/7316/929/3656/10454/7189/6233/7311/353376/7314/148022/257397 15 Human_rhinovirus_A_serotype_89 R-HSA-6802957 Oncogenic MAPK signaling 33/1200 71/10654 8.829222788129146e-14 8.445938698101834e-13 4.034569368708545e-13 4000/27044/818/815/4893/71/5604/10018/10142/283455/8844/817/5594/10533/673/8315/6714/5037/3717/2335/3690/408/816/4296/5894/4140/3845/3265/369/801/5245/7529/5595 33 Human_rhinovirus_A_serotype_89 R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 38/1200 92/10654 1.266977697208428e-13 1.2026542141193847e-12 5.745000084507851e-13 1017/6118/5563/5883/1459/8445/22974/9212/51422/1460/545/53632/7316/1457/6790/641/4194/112858/6119/3364/1432/5571/10524/6794/1111/7157/6233/672/7311/5562/8851/6117/5564/5565/1020/5810/7314/4193 38 Human_rhinovirus_A_serotype_89 R-HSA-5621575 CD209 (DC-SIGN) signaling 17/1200 21/10654 2.6232184662491957e-013 2.4710317460698533e-12 1.180395613579389e-12 9252/4893/4790/5567/3384/5970/5566/1387/4067/5063/2534/2033/5894/3845/3265/5058/5062 17 Human_rhinovirus_A_serotype_89 R-HSA-209543 p75NTR recruits signalling complexes 13/1200 13/10654 4.4314343833831007e-13 4.050659280810924e-12 1.934973298007436e-12 4804/5584/8767/8878/4615/7316/4803/3654/7189/6233/7311/3551/7314 13 Human_rhinovirus_A_serotype_89 R-HSA-209560 NF-kB is activated and signals survival 13/1200 13/10654 4.4314343833831007e-13 4.050659280810924e-12 1.934973298007436e-12 4804/4790/8878/7316/5970/4792/4803/3654/7189/6233/7311/3551/7314 13 Human_rhinovirus_A_serotype_89 R-HSA-5357786 TNFR1-induced proapoptotic signaling 13/1200 13/10654 4.4314343833831007e-13 4.050659280810924e-12 1.934973298007436e-12 7124/7186/56957/8737/7375/841/27005/7128/7132/9099/8772/8717/1540 13 Human_rhinovirus_A_serotype_89 R-HSA-8847993 ERBB2 Activates PTK6 Signaling 13/1200 13/10654 4.4314343833831007e-13 4.050659280810924e-12 1.934973298007436e-12 1839/685/2065/2069/2064/1950/5753/145957/3084/2066/9542/10718/1956 13 Human_rhinovirus_A_serotype_89 R-HSA-933542 TRAF6 mediated NF-kB activation 18/1200 24/10654 5.247629634131402e-13 4.761452182733934e-12 2.274514392502775e-12 1147/351/7186/4790/57506/4214/7706/8517/5970/4792/4793/3146/23586/64135/7189/84282/3551/4791 18 Human_rhinovirus_A_serotype_89 R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 15/1200 17/10654 6.010641876335558e-13 5.413965018538744e-12 2.586215482710651e-12 23643/6885/23118/7099/7316/929/3656/10454/7189/6233/7311/353376/7314/148022/257397 15 Human_rhinovirus_A_serotype_89 R-HSA-937039 IRAK1 recruits IKK complex 14/1200 15/10654 6.643468192784071e-13 5.897870323665859e-12 2.8173738644142974e-12 1147/246330/8517/7316/7335/57162/3654/7189/6233/7311/7334/3551/57161/7314 14 Human_rhinovirus_A_serotype_89 R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 14/1200 15/10654 6.643468192784071e-13 5.897870323665859e-12 2.8173738644142974e-12 1147/246330/8517/7316/7335/57162/3654/7189/6233/7311/7334/3551/57161/7314 14 Human_rhinovirus_A_serotype_89 R-HSA-453279 Mitotic G1-G1/S phases 49/1200 149/10654 1.2077259271184009e-12 1.0645241386172191e-11 5.085161798393267e-12 8454/1017/4172/6118/25/894/1019/5684/1029/5707/207/1027/6500/5925/4149/7316/4174/5753/983/1026/6714/4171/4609/6119/5688/4067/3717/6502/10000/5686/1021/1874/595/5710/208/6233/7298/5716/1030/7311/5518/6117/7465/1163/1022/5693/7314/5515/6241 49 Human_rhinovirus_A_serotype_89 R-HSA-9614085 FOXO-mediated transcription 30/1200 65/10654 1.4993377768753651e-12 1.3121863947973054e-11 6.2682281078776e-12 2308/857/2309/65018/10018/356/7532/207/4303/1027/2810/4287/6720/7534/847/1026/1387/2908/10000/6794/2033/3630/3066/4087/91584/208/604/23411/25942/7529 30 Human_rhinovirus_A_serotype_89 R-HSA-983705 Signaling by the B Cell Receptor (BCR) 41/1200 112/10654 1.6419296531536623e-12 1.4268599943602951e-11 6.8160163511197245e-012 5295/8454/1147/8945/5684/4893/4790/6885/5579/5966/5707/640/84433/6500/10892/3708/8517/7316/5970/4792/4793/8915/5688/4067/23291/5686/2534/5710/695/6654/6233/2885/5716/7311/4794/3845/3265/3551/801/5693/7314 41 Human_rhinovirus_A_serotype_89 R-HSA-5654741 Signaling by FGFR3 23/1200 40/10654 1.6882203124724454e-12 1.4568278780356628e-11 6.959170960504744e-12 5295/4893/6464/5290/5335/5594/7316/673/6714/10818/2261/867/6654/6233/2885/7311/5518/3845/2549/3265/7314/5595/5515 23 Human_rhinovirus_A_serotype_89 R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 26/1200 51/10654 2.5869495972264163e-12 2.2168720854009706e-11 1.0589852152388839e-11 79861/11258/1783/10382/93661/55860/830/7277/10671/1780/5048/1781/8655/84516/1639/832/10121/7846/347733/51143/10540/10383/140735/829/51164/1778 26 Human_rhinovirus_A_serotype_89 R-HSA-5654743 Signaling by FGFR4 23/1200 41/10654 3.4383118096941722e-12 2.926121912525937e-11 1.3977891930517141e-11 5295/4893/6464/5290/5335/5594/7316/673/6714/10818/867/2264/6654/6233/2885/7311/5518/3845/2549/3265/7314/5595/5515 23 Human_rhinovirus_A_serotype_89 R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 32/1200 75/10654 3.81616363847483e-12 3.225442417724617e-11 1.5407726298095925e-11 5295/1839/685/5290/3667/5291/2065/2069/2064/2260/2100/1950/4233/6714/2099/10818/2261/5159/145957/3084/2534/2264/2066/9542/2885/10718/8660/3932/1956/2549/5156/5879 32 Human_rhinovirus_A_serotype_89 R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12/1200 12/10654 3.969640126932924e-12 3.3141475291657615e-11 1.5831464781479366e-11 1147/8737/57506/841/7706/8517/23586/843/64135/84282/8772/3551 12 Human_rhinovirus_A_serotype_89 R-HSA-6802952 Signaling by BRAF and RAF fusions 30/1200 67/10654 3.974828479064284e-12 3.3141475291657615e-11 1.5831464781479366e-11 4000/27044/818/815/4893/71/5604/10018/10142/283455/8844/817/5594/10533/673/6714/5037/3717/2335/3690/408/816/5894/4140/3845/3265/369/801/7529/5595 30 Human_rhinovirus_A_serotype_89 R-HSA-3371568 Attenuation phase 13/1200 14/10654 5.56138560154242e-12 4.6058723706733874e-11 2.2001949395010633e-11 3303/3337/3305/1387/3320/2033/3326/3306/3304/3312/3297/2288/10728 13 Human_rhinovirus_A_serotype_89 R-HSA-3371453 Regulation of HSF1-mediated heat shock response 30/1200 69/10654 1.0049577232088157e-11 8.26745220293119e-11 3.9493075438381525e-11 3303/6118/81929/7531/5594/9530/3308/545/3337/3313/10808/3305/9261/9532/6119/2932/3310/3309/7266/6767/9531/22824/3306/23411/6117/3304/3312/3297/51182/5595 30 Human_rhinovirus_A_serotype_89 R-HSA-389356 CD28 co-stimulation 20/1200 33/10654 1.2601591780820884e-11 1.0298254475187398e-10 4.919408433084485e-11 5295/5170/1326/5290/207/9020/6714/4067/10000/5063/2534/208/2885/7525/2475/3932/5058/5062/5879/253260 20 Human_rhinovirus_A_serotype_89 R-HSA-194315 Signaling by Rho GTPases 100/1200 455/10654 1.600041142035217e-11 1.298980769257538e-10 6.205145703183667e-11 26999/5170/11130/25/81929/5590/1072/3984/79861/54908/71/5579/1499/25936/7531/5747/80776/1783/10006/4627/2316/7532/10928/10458/4771/5578/10382/9212/5594/3985/613/1027/1080/2810/7277/79980/6232/7534/332/1780/5048/1781/8655/5289/5585/4168/10152/6279/6714/8936/1432/10163/7846/999/396/10810/347733/22919/55845/5063/9475/995/3895/79003/11243/23221/51143/695/6654/90627/8976/2885/5580/23191/7514/6093/57120/367/5518/10383/54820/5347/387/23332/5058/801/3071/9793/10726/30849/5586/5062/140735/9886/7529/10787/5879/5595/5515/1778 100 Human_rhinovirus_A_serotype_89 R-HSA-5675221 Negative regulation of MAPK pathway 22/1200 40/10654 1.7456871544655317e-11 1.4079594435362522e-10 6.725729662887498e-11 4893/5604/8844/5594/7316/673/8315/5037/5894/6233/7311/5518/5536/4140/1843/3845/3265/369/7529/7314/5595/5515 22 Human_rhinovirus_A_serotype_89 R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 33/1200 83/10654 1.8234707755462135e-11 1.4611447643013167e-10 6.979792442282156e-11 8454/1147/8945/5684/4893/4790/6885/5579/5966/5707/84433/6500/10892/8517/7316/5970/4792/4793/8915/5688/23291/5686/5710/6233/5716/7311/4794/3845/3265/3551/801/5693/7314 33 Human_rhinovirus_A_serotype_89 R-HSA-6806003 Regulation of TP53 Expression and Degradation 21/1200 37/10654 2.241856268655859e-11 1.7848068616266645e-10 8.525904994548597e-11 1017/5170/1029/6446/207/639/7316/983/4194/9099/10000/7157/208/6233/2475/7311/5518/7314/253260/4193/5515 21 Human_rhinovirus_A_serotype_89 R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 14/1200 17/10654 2.4180209424089876e-11 1.912716565982494e-10 9.136921239872017e-11 1147/11035/4790/8737/8517/4615/7098/5970/4792/4793/81030/3551/4791/148022 14 Human_rhinovirus_A_serotype_89 R-HSA-6807070 PTEN Regulation 45/1200 140/10654 2.4434127860060768e-11 1.9129300403760637e-10 9.137940993010284e-11 27161/3725/5684/5468/1822/1459/5707/2146/10273/207/6045/5594/1460/192670/7316/1457/8658/4734/10014/5688/10000/5686/5728/6009/2444/5710/6615/192669/3066/7157/1107/8975/5987/208/6233/2475/5716/7311/1386/331/26523/57521/5693/7314/5595 45 Human_rhinovirus_A_serotype_89 R-HSA-69620 Cell Cycle Checkpoints 73/1200 293/10654 2.449294541162221e-11 1.9129300403760637e-10 9.137940993010284e-11 1017/4172/6118/11130/81929/5684/54908/5883/25936/7531/51512/1029/80776/1783/7321/5707/7532/9212/1027/2810/545/79980/6232/7534/332/1780/5048/1781/7316/4174/8655/983/1026/641/4171/4194/6119/3364/10524/5688/22919/5686/995/79003/11243/5710/51143/1111/7157/6233/5716/672/7514/7311/9025/5518/54820/5347/6117/29882/7334/23332/7465/9793/10726/5810/5693/140735/7529/7314/4193/5515/1778 73 Human_rhinovirus_A_serotype_89 R-HSA-1169091 Activation of NF-kappaB in B cells 29/1200 67/10654 2.5505317903200778e-11 1.9794693265754566e-10 9.455794787019157e-11 8454/1147/8945/5684/4790/6885/5579/5966/5707/84433/6500/10892/8517/7316/5970/4792/4793/8915/5688/23291/5686/5710/6233/5716/7311/4794/3551/5693/7314 29 Human_rhinovirus_A_serotype_89 R-HSA-9006115 Signaling by NTRK2 (TRKB) 17/1200 25/10654 3.0434551426422445e-11 2.347264778762831e-10 1.121272947289248e-10 5295/4893/6464/5290/5335/4915/6714/10818/2534/6654/2885/8851/3845/2549/3265/1020/5879 17 Human_rhinovirus_A_serotype_89 R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 24/1200 48/10654 3.0944445586879196e-11 2.3717668232427903e-10 1.1329774127919155e-10 5295/6464/5290/1437/5291/1439/1438/7534/7316/3055/5566/867/3558/4067/3717/2534/6654/6233/2885/7525/1398/3716/7311/7314 24 Human_rhinovirus_A_serotype_89 R-HSA-3371378 Regulation by c-FLIP 11/1200 11/10654 3.5533120160594664e-11 2.641437968564688e-10 1.261797545335004e-10 7186/8737/356/355/841/8797/8837/8772/8717/8743/8795 11 Human_rhinovirus_A_serotype_89 R-HSA-5218900 CASP8 activity is inhibited 11/1200 11/10654 3.5533120160594664e-11 2.641437968564688e-10 1.261797545335004e-10 7186/8737/356/355/841/8797/8837/8772/8717/8743/8795 11 Human_rhinovirus_A_serotype_89 R-HSA-5655291 Signaling by FGFR4 in disease 11/1200 11/10654 3.5533120160594664e-11 2.641437968564688e-10 1.261797545335004e-10 5295/4893/5290/5335/10818/2264/6654/2885/3845/2549/3265 11 Human_rhinovirus_A_serotype_89 R-HSA-69416 Dimerization of procaspase-8 11/1200 11/10654 3.5533120160594664e-11 2.641437968564688e-10 1.261797545335004e-10 7186/8737/356/355/841/8797/8837/8772/8717/8743/8795 11 Human_rhinovirus_A_serotype_89 R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 11/1200 11/10654 3.5533120160594664e-11 2.641437968564688e-10 1.261797545335004e-10 6885/23118/7098/7316/10454/7189/6233/7311/7314/148022/257397 11 Human_rhinovirus_A_serotype_89 R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 30/1200 72/10654 3.7260842700221485e-11 2.746541541954959e-10 1.3120048310967986e-10 6517/8773/5563/79861/71/7531/4627/7532/207/10382/51422/2810/7277/53632/7534/8766/60412/149371/5571/7846/347733/208/10383/5564/801/5565/4218/7529/5879/55770 30 Human_rhinovirus_A_serotype_89 R-HSA-6785631 ERBB2 Regulates Cell Motility 13/1200 15/10654 3.739213768625876e-11 2.746541541954959e-10 1.3120048310967986e-10 1839/685/2065/2069/2064/1950/145957/3084/2066/9542/10718/387/1956 13 Human_rhinovirus_A_serotype_89 R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 12/1200 13/10654 4.628760039006821e-11 3.379816501854685e-10 1.6145161145087635e-10 2065/207/10193/2064/7316/10000/3084/208/9542/6233/7311/7314 12 Human_rhinovirus_A_serotype_89 R-HSA-388841 Costimulation by the CD28 family 29/1200 70/10654 9.349613855240762e-11 6.786719704333589e-10 3.2419713677615027e-10 5295/5170/1326/5290/207/3123/3126/3115/3122/9020/920/6714/4067/10000/5063/2534/208/2885/7525/2475/3932/5518/3127/3125/5058/5062/5879/253260/5515 29 Human_rhinovirus_A_serotype_89 R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 14/1200 18/10654 9.75056541645357e-11 6.995463792967271e-10 3.3416870460306e-10 1839/4893/5578/5594/5598/6195/6654/2885/6196/1956/6197/3845/3265/5595 14 Human_rhinovirus_A_serotype_89 R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 14/1200 18/10654 9.75056541645357e-11 6.995463792967271e-10 3.3416870460306e-10 23643/29110/7099/7316/929/3661/6233/10010/7311/7187/9641/353376/7314/148022 14 Human_rhinovirus_A_serotype_89 R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 20/1200 36/10654 1.1503775489396491e-10 8.1584246861582e-10 3.897225816129482e-10 26999/25/71/5747/10006/10458/5594/10152/8936/10163/10810/55845/695/8976/2885/23191/3071/10787/5879/5595 20 Human_rhinovirus_A_serotype_89 R-HSA-6804757 Regulation of TP53 Degradation 20/1200 36/10654 1.1503775489396491e-10 8.1584246861582e-10 3.897225816129482e-10 1017/5170/1029/6446/207/7316/983/4194/9099/10000/7157/208/6233/2475/7311/5518/7314/253260/4193/5515 20 Human_rhinovirus_A_serotype_89 R-HSA-8878166 Transcriptional regulation by RUNX2 40/1200 121/10654 1.1992597185910627e-10 8.456494244236408e-10 4.0396116836751585e-10 8454/7291/25/1019/5684/5707/10273/207/5594/3280/6500/5925/10013/7316/11059/9759/983/1026/10413/6714/2099/2932/5688/6502/2908/10000/5686/595/55294/5710/208/6233/7525/5716/7311/367/1750/5693/7314/5595 40 Human_rhinovirus_A_serotype_89 R-HSA-5218921 VEGFR2 mediated cell proliferation 15/1200 21/10654 1.5437488458908643e-10 1.0823784521757537e-9 5.170450680017248e-10 5170/5590/4893/5335/5579/7422/5578/3708/6714/5580/3791/3845/3265/801/8877 15 Human_rhinovirus_A_serotype_89 R-HSA-5687128 MAPK6/MAPK4 signaling 33/1200 89/10654 1.6610776308682454e-10 1.1580620319160536e-9 5.531986162867781e-10 2308/27161/3725/5684/2309/5707/5567/3315/3337/192670/5596/7316/983/5597/4609/5566/5688/5686/5063/5710/192669/6233/5716/7514/7311/5896/26523/5058/8202/5062/5693/7314/5879 33 Human_rhinovirus_A_serotype_89 R-HSA-114452 Activation of BH3-only proteins 18/1200 30/10654 1.7325508796005595e-10 1.2011054974309497e-9 5.737601966743425e-10 596/10018/7531/572/7532/207/2810/7534/8655/10000/7157/8626/208/7161/5599/7159/140735/7529 18 Human_rhinovirus_A_serotype_89 R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 16/1200 24/10654 1.864455068046243e-10 1.2853282424408178e-9 6.1399284804816e-10 596/1839/685/2309/5747/207/5594/2069/1027/1950/10000/595/208/7514/1956/5595 16 Human_rhinovirus_A_serotype_89 R-HSA-198323 AKT phosphorylates targets in the cytosol 12/1200 14/10654 2.9064488912122287e-10 1.981523719202149e-9 9.465608485483267e-10 1147/842/572/207/1027/7249/1026/2932/10000/208/2931/4193 12 Human_rhinovirus_A_serotype_89 R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 12/1200 14/10654 2.9064488912122287e-10 1.981523719202149e-9 9.465608485483267e-10 4893/1793/5753/1398/9844/387/9564/3845/3265/63916/5829/5879 12 Human_rhinovirus_A_serotype_89 R-HSA-187687 Signalling to ERKs 19/1200 34/10654 2.9509456663723417e-10 2.000806017749159e-9 9.557718757481268e-10 4893/6464/5604/5594/673/9261/6714/10818/7867/1432/4914/4803/6654/2885/1398/3845/3265/7529/5595 19 Human_rhinovirus_A_serotype_89 R-HSA-1250342 PI3K events in ERBB4 signaling 10/1200 10/10654 3.178273369658562e-10 2.108596418364874e-9 1.0072626412047508e-9 5295/1839/685/5290/2069/145957/3084/2066/9542/10718 10 Human_rhinovirus_A_serotype_89 R-HSA-193697 p75NTR regulates axonogenesis 10/1200 10/10654 3.178273369658562e-10 2.108596418364874e-9 1.0072626412047508e-9 4804/57142/4974/65078/4168/84894/396/4803/4099/387 10 Human_rhinovirus_A_serotype_89 R-HSA-8853334 Signaling by FGFR3 fusions in cancer 10/1200 10/10654 3.178273369658562e-10 2.108596418364874e-9 1.0072626412047508e-9 5295/4893/5290/10818/2261/6654/2885/3845/2549/3265 10 Human_rhinovirus_A_serotype_89 R-HSA-937042 IRAK2 mediated activation of TAK1 complex 10/1200 10/10654 3.178273369658562e-10 2.108596418364874e-9 1.0072626412047508e-9 6885/23118/7316/3656/10454/7189/6233/7311/7314/257397 10 Human_rhinovirus_A_serotype_89 R-HSA-3371511 HSF1 activation 11/1200 12/10654 3.8273140053087197e-10 2.5121837673143405e-9 1.2000536634786578e-9 6118/7531/1915/10013/7415/6119/3320/3326/6117/3297/10728 11 Human_rhinovirus_A_serotype_89 R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 11/1200 12/10654 3.8273140053087197e-10 2.5121837673143405e-9 1.2000536634786578e-9 29110/7098/7316/3661/6233/10010/7311/7187/9641/7314/148022 11 Human_rhinovirus_A_serotype_89 R-HSA-373755 Semaphorin interactions 27/1200 65/10654 3.870887686109996e-10 2.52734148394695e-9 1.2072944050245604e-9 1400/1072/3984/5361/4627/3985/10371/2064/8829/4233/2932/55558/3320/5063/2534/9475/91584/3326/6093/5362/387/8851/5058/1020/5062/5879/2242 27 Human_rhinovirus_A_serotype_89 R-HSA-9006335 Signaling by Erythropoietin 16/1200 25/10654 4.6379831636587235e-10 3.0122480126078236e-9 1.4389310646254212e-9 5295/4893/6464/5290/5335/5291/4067/23533/3717/5294/6654/2885/8660/3845/2549/3265 16 Human_rhinovirus_A_serotype_89 R-HSA-69206 G1/S Transition 41/1200 131/10654 4.731664934100493e-10 3.0570023710366535e-9 1.460309927305746e-9 8454/1017/4172/6118/1019/5684/5707/207/1027/6500/5925/4149/7316/4174/5753/983/1026/4171/4609/6119/5688/6502/10000/5686/1874/595/5710/208/6233/7298/5716/7311/5518/6117/7465/1163/1022/5693/7314/5515/6241 41 Human_rhinovirus_A_serotype_89 R-HSA-2559583 Cellular Senescence 53/1200 195/10654 4.966630561167481e-10 3.1920948502503497e-9 1.5248427161479109e-9 1017/7014/3725/25913/1019/4790/5606/9448/3159/1029/7321/2146/6045/5594/1027/5925/7013/50488/192670/3576/3490/7316/6774/5970/1026/9261/6667/7867/4194/5598/1432/10524/1021/6195/192669/7157/5609/6233/1030/51343/6196/7311/6197/29882/5599/4217/26523/5608/3569/7314/5595/4193/23043 53 Human_rhinovirus_A_serotype_89 R-HSA-5654736 Signaling by FGFR1 23/1200 50/10654 6.719858352924511e-10 4.296531195600438e-9 2.052424694648337e-9 5295/4893/6464/5290/5335/5594/2260/7316/673/6714/10818/867/6654/6233/2885/7311/5518/3845/2549/3265/7314/5595/5515 23 Human_rhinovirus_A_serotype_89 R-HSA-74751 Insulin receptor signalling cascade 24/1200 54/10654 6.8783608339785e-10 4.375204777901788e-9 2.090006547492111e-9 5295/5170/4893/6464/5290/3667/5291/5594/2322/2260/5289/10818/2261/2264/3630/208/6654/2885/8660/3845/2549/3265/30849/5595 24 Human_rhinovirus_A_serotype_89 R-HSA-5689880 Ub-specific processing proteases 57/1200 220/10654 8.094475087350008e-10 5.122349875789697e-9 2.4469128469182206e-9 23032/5684/7186/6885/51651/2648/5707/8737/7375/2625/9817/4303/91833/1080/330/3091/11274/27005/8517/7316/7417/4792/9738/8658/8678/9100/4609/4194/23586/5688/9097/329/7046/6502/9099/5686/408/64135/5728/5710/10454/7157/10869/8975/4087/7189/6233/5716/9804/7311/367/23770/8607/1540/5693/7314/4193 57 Human_rhinovirus_A_serotype_89 R-HSA-5205647 Mitophagy 17/1200 29/10654 9.380643338953918e-10 5.877952297270972e-9 2.807859154202631e-9 65018/1459/9140/8878/10452/1460/9474/7316/1457/6714/8408/81631/6233/9804/7311/84557/7314 17 Human_rhinovirus_A_serotype_89 R-HSA-1433557 Signaling by SCF-KIT 21/1200 43/10654 9.383765012661113e-10 5.877952297270972e-9 2.807859154202631e-9 5295/4893/5290/5578/2241/9306/6774/6714/867/4067/3717/2534/1111/6654/2885/7525/3932/3845/3265/5879/2242 21 Human_rhinovirus_A_serotype_89 R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 31/1200 85/10654 9.59200763955093e-10 5.978049205659519e-9 2.8556747890210106e-9 8454/1017/1019/5684/5707/207/1027/6500/5925/4149/7316/5753/1026/4609/5688/6502/10000/5686/1874/595/5710/208/6233/5716/51343/7311/7465/1163/1022/5693/7314 31 Human_rhinovirus_A_serotype_89 R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 19/1200 36/10654 1.0946966510021888e-9 6.788219433852768e-9 3.2426877786893713e-9 4893/71/5604/283455/8844/5594/673/6714/5037/2335/3690/408/5894/4140/3845/3265/369/7529/5595 19 Human_rhinovirus_A_serotype_89 R-HSA-9006931 Signaling by Nuclear Receptors 70/1200 299/10654 1.2087709577646363e-9 7.458116809407805e-9 3.562693349201033e-9 5295/5170/27161/3725/596/5434/5590/1839/4893/6464/685/857/5290/7090/5241/2309/5747/8204/207/2625/5594/2069/1027/3315/5481/6720/192670/5885/2100/4313/1950/2194/6667/2289/6714/2099/4609/10524/1387/5467/10000/3320/2033/8243/4846/9126/595/192669/2066/2771/208/3326/7514/1025/1386/1956/5536/3169/3845/858/3265/26523/801/8202/8877/3480/2288/10728/10062/5595 70 Human_rhinovirus_A_serotype_89 R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 12/1200 15/10654 1.3036558948610759e-9 8.003539175415759e-9 3.8232380263011385e-9 6737/29110/81844/23220/147945/7316/22954/3661/6233/7311/81030/7314 12 Human_rhinovirus_A_serotype_89 R-HSA-2559585 Oncogene Induced Senescence 18/1200 33/10654 1.4897938891292063e-9 9.101018114779409e-9 4.347496497719414e-9 1019/1029/5594/5925/192670/7316/6667/4194/1021/192669/7157/6233/1030/7311/26523/7314/5595/4193 18 Human_rhinovirus_A_serotype_89 R-HSA-68882 Mitotic Anaphase 53/1200 201/10654 1.6274346891814682e-9 9.892878849507053e-9 4.725763162777403e-9 4000/11130/81929/5684/79861/54908/25936/80776/55869/1783/7321/5707/10382/9212/7277/79980/6232/332/1780/5885/5048/1781/7316/8655/5688/7846/347733/22919/5686/79003/8243/9126/11243/5710/51143/6233/5716/7514/7311/5518/10383/54820/5347/29882/23332/9793/10726/7112/5693/140735/7314/5515/1778 53 Human_rhinovirus_A_serotype_89 R-HSA-2467813 Separation of Sister Chromatids 51/1200 190/10654 1.6990172467467892e-9 1.0277388639634989e-8 4.909440960671836e-9 11130/81929/5684/79861/54908/25936/80776/55869/1783/7321/5707/10382/9212/7277/79980/6232/332/1780/5885/5048/1781/7316/8655/5688/7846/347733/22919/5686/79003/8243/9126/11243/5710/51143/6233/5716/7514/7311/5518/10383/54820/5347/29882/23332/9793/10726/5693/140735/7314/5515/1778 51 Human_rhinovirus_A_serotype_89 R-HSA-2500257 Resolution of Sister Chromatid Cohesion 39/1200 126/10654 1.7986158633189273e-9 1.082679012358808e-8 5.171886436244412e-9 11130/81929/79861/54908/25936/80776/55869/1783/10382/9212/7277/79980/6232/332/1780/5885/5048/1781/8655/983/7846/347733/22919/79003/8243/9126/11243/51143/7514/5518/10383/54820/5347/23332/9793/10726/140735/5515/1778 39 Human_rhinovirus_A_serotype_89 R-HSA-2555396 Mitotic Metaphase and Anaphase 53/1200 202/10654 1.970893686714957e-9 1.180622723012746e-8 5.639757100461807e-9 4000/11130/81929/5684/79861/54908/25936/80776/55869/1783/7321/5707/10382/9212/7277/79980/6232/332/1780/5885/5048/1781/7316/8655/5688/7846/347733/22919/5686/79003/8243/9126/11243/5710/51143/6233/5716/7514/7311/5518/10383/54820/5347/29882/23332/9793/10726/7112/5693/140735/7314/5515/1778 53 Human_rhinovirus_A_serotype_89 R-HSA-69202 Cyclin E associated events during G1/S transition 30/1200 83/10654 2.2925447439600503e-9 1.3666667700708706e-8 6.528477277486032e-9 8454/1017/1019/5684/5707/207/1027/6500/5925/4149/7316/5753/1026/4609/5688/6502/10000/5686/1874/595/5710/208/6233/5716/7311/7465/1163/1022/5693/7314 30 Human_rhinovirus_A_serotype_89 R-HSA-2428924 IGF1R signaling cascade 23/1200 53/10654 2.7734867814095425e-9 1.6454243693554688e-8 7.86008399589749e-9 5295/5170/4893/6464/5290/3667/5291/2322/2260/5289/10818/2261/8471/2264/208/6654/2885/8660/3845/2549/3265/30849/3480 23 Human_rhinovirus_A_serotype_89 R-HSA-177929 Signaling by EGFR 22/1200 49/10654 2.802434402876763e-9 1.654643087631543e-8 7.904121206804267e-9 5295/1839/4893/6464/685/5290/5335/2069/7316/1950/6714/867/6654/6233/2885/7311/1956/3845/2549/3265/5829/7314 22 Human_rhinovirus_A_serotype_89 R-HSA-5603041 IRAK4 deficiency (TLR2/4) 10/1200 11/10654 3.1407695050184824e-9 1.8281648911286827e-8 8.733023449902434e-9 23643/10333/7099/4615/7096/929/114609/695/51135/7097 10 Human_rhinovirus_A_serotype_89 R-HSA-9614399 Regulation of localization of FOXO transcription factors 10/1200 11/10654 3.1407695050184824e-9 1.8281648911286827e-8 8.733023449902434e-9 2308/2309/7532/207/4303/2810/7534/10000/208/7529 10 Human_rhinovirus_A_serotype_89 R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 10/1200 11/10654 3.1407695050184824e-9 1.8281648911286827e-8 8.733023449902434e-9 6885/23118/7316/80216/10454/7189/6233/7311/7314/257397 10 Human_rhinovirus_A_serotype_89 R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 35/1200 108/10654 3.1577354405370386e-9 1.8294110486491574e-8 8.73897626242027e-9 5295/7124/2308/7291/596/2309/7412/7184/356/207/5292/7422/2625/4582/3091/6778/3576/332/4313/6774/1026/4609/3717/598/3320/4843/2335/595/7157/3716/604/3312/7297/3569/4170 35 Human_rhinovirus_A_serotype_89 R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 23/1200 54/10654 4.320905041224671e-9 2.491587299472544e-8 1.1902148662497863e-8 5295/5170/4893/6464/5290/3667/5291/2322/2260/5289/10818/2261/8471/2264/208/6654/2885/8660/3845/2549/3265/30849/3480 23 Human_rhinovirus_A_serotype_89 R-HSA-1295596 Spry regulation of FGF signaling 12/1200 16/10654 4.67825654409293e-9 2.6726706367642015e-8 1.276717185522437e-8 5594/7316/673/6714/867/6233/2885/7311/5518/7314/5595/5515 12 Human_rhinovirus_A_serotype_89 R-HSA-399956 CRMPs in Sema3A signaling 12/1200 16/10654 4.67825654409293e-9 2.6726706367642015e-8 1.276717185522437e-8 1400/5361/10371/8829/2932/55558/2534/91584/5362/8851/1020/2242 12 Human_rhinovirus_A_serotype_89 R-HSA-912631 Regulation of signaling by CBL 14/1200 22/10654 6.573646133311859e-9 3.738193238943241e-8 1.7857103248385356e-8 5295/5290/5291/7316/3055/867/4067/2534/6233/2885/7525/1398/7311/7314 14 Human_rhinovirus_A_serotype_89 R-HSA-2871796 FCERI mediated MAPK activation 17/1200 32/10654 7.3403594024715705e-9 4.1550474782797784e-8 1.984838853396465e-8 3725/4893/6464/5335/5594/4214/4067/5609/6654/2885/3845/5599/3265/5058/5062/5879/5595 17 Human_rhinovirus_A_serotype_89 R-HSA-193704 p75 NTR receptor-mediated signalling 32/1200 97/10654 9.126884686929417e-9 5.142728631813197e-8 2.4566476446433422e-8 4804/57142/4790/5584/10018/7531/572/8767/4974/8878/4615/7316/5970/4792/65078/4168/84894/836/396/4803/3066/3654/7189/6654/4099/6233/7311/387/5599/3551/7314/5879 32 Human_rhinovirus_A_serotype_89 R-HSA-180336 SHC1 events in EGFR signaling 11/1200 14/10654 9.355772812646941e-9 5.223992602174808e-8 2.4954669088270003e-8 1839/4893/6464/685/2069/1950/6654/2885/1956/3845/3265 11 Human_rhinovirus_A_serotype_89 R-HSA-918233 TRAF3-dependent IRF activation pathway 11/1200 14/10654 9.355772812646941e-9 5.223992602174808e-8 2.4954669088270003e-8 29110/57506/7706/23586/1387/2033/64135/3661/84282/7187/9641 11 Human_rhinovirus_A_serotype_89 R-HSA-186763 Downstream signal transduction 16/1200 29/10654 9.913094872296503e-9 5.461053157327627e-8 2.6087091769201326e-8 5295/4893/5290/5335/5291/6778/6774/6714/5159/6654/2885/1398/9564/3845/3265/5156 16 Human_rhinovirus_A_serotype_89 R-HSA-5218920 VEGFR2 mediated vascular permeability 16/1200 29/10654 9.913094872296503e-9 5.461053157327627e-8 2.6087091769201326e-8 5170/857/1499/207/10000/3320/5063/4846/3728/208/2475/5058/801/5062/5879/253260 16 Human_rhinovirus_A_serotype_89 R-HSA-9619483 Activation of AMPK downstream of NMDARs 16/1200 29/10654 9.913094872296503e-9 5.461053157327627e-8 2.6087091769201326e-8 5563/79861/10382/51422/7277/53632/10645/5571/7846/347733/4137/5562/10383/5564/801/5565 16 Human_rhinovirus_A_serotype_89 R-HSA-165159 mTOR signalling 19/1200 40/10654 1.0723904100576146e-8 5.855441442526975e-8 2.7971058669411466e-8 5563/6194/207/51422/7249/53632/6198/5571/6794/6009/208/2475/5562/92335/5564/5565/57521/7248/7529 19 Human_rhinovirus_A_serotype_89 R-HSA-5674135 MAP2K and MAPK activation 19/1200 40/10654 1.0723904100576146e-8 5.855441442526975e-8 2.7971058669411466e-8 4893/71/5604/283455/8844/5594/673/6714/5037/2335/3690/408/5894/4140/3845/3265/369/7529/5595 19 Human_rhinovirus_A_serotype_89 R-HSA-2428928 IRS-related events triggered by IGF1R 22/1200 52/10654 1.0918561742829671e-8 5.9354648416968345e-8 2.835332518425511e-8 5295/5170/4893/5290/3667/5291/2322/2260/5289/10818/2261/8471/2264/208/6654/2885/8660/3845/2549/3265/30849/3480 22 Human_rhinovirus_A_serotype_89 R-HSA-9034015 Signaling by NTRK3 (TRKC) 12/1200 17/10654 1.427102996322914e-8 7.723882006414369e-8 3.689647635922585e-8 5295/4893/6464/5290/3667/5335/6714/6654/2885/3845/3265/4916 12 Human_rhinovirus_A_serotype_89 R-HSA-2562578 TRIF-mediated programmed cell death 9/1200 10/10654 2.5546539710393294e-8 1.3706273914184924e-7 6.54739690518089e-8 23643/11035/8737/841/7099/929/8772/353376/148022 9 Human_rhinovirus_A_serotype_89 R-HSA-5602498 MyD88 deficiency (TLR2/4) 9/1200 10/10654 2.5546539710393294e-8 1.3706273914184924e-7 6.54739690518089e-8 23643/10333/7099/4615/7096/929/114609/695/7097 9 Human_rhinovirus_A_serotype_89 R-HSA-5628897 TP53 Regulates Metabolic Genes 29/1200 86/10654 2.5908185193154e-8 1.3840130098853695e-7 6.611339124249823e-8 27161/5563/7531/7532/207/51422/7249/2810/53632/192670/7534/54205/5571/10000/10128/5728/6009/192669/7157/8626/208/2475/5562/26523/5564/5565/57521/7248/7529 29 Human_rhinovirus_A_serotype_89 R-HSA-9006936 Signaling by TGF-beta family members 32/1200 102/10654 3.5815446272845515e-8 1.9050112370987657e-7 9.100113390559658e-8 5590/7321/10273/4738/269/130399/54778/7316/91/93/6667/4609/22938/23327/867/23645/7046/1874/94/9040/4087/5499/657/6233/7514/7048/1025/1030/7311/387/23439/7314 32 Human_rhinovirus_A_serotype_89 R-HSA-445144 Signal transduction by L1 13/1200 21/10654 3.766224917028263e-8 1.991820689041695e-7 9.514796433194143e-8 5604/1459/5594/1460/2260/8829/1457/3690/3685/1956/5058/5879/5595 13 Human_rhinovirus_A_serotype_89 R-HSA-69242 S Phase 43/1200 161/10654 3.777034369819746e-8 1.991820689041695e-7 9.514796433194143e-8 8454/1017/4172/6118/1019/5684/7321/5707/207/1027/6500/5925/4149/5885/7316/4174/5753/1026/4171/4609/6119/2932/5688/6502/10000/5686/1874/8243/9126/595/5710/208/6233/5716/51343/7311/6117/29882/7465/1163/1022/5693/7314 43 Human_rhinovirus_A_serotype_89 R-HSA-170834 Signaling by TGF-beta Receptor Complex 26/1200 73/10654 3.801665268754896e-8 1.9962786985717198e-7 9.536092051524038e-8 5590/7321/10273/4738/54778/7316/6667/4609/22938/23327/867/23645/7046/1874/9040/4087/5499/6233/7514/7048/1025/1030/7311/387/23439/7314 26 Human_rhinovirus_A_serotype_89 R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 20/1200 47/10654 4.523944933432344e-8 2.3654864609557255e-7 1.1299773250321644e-7 8454/7090/2648/55869/3280/6500/3091/10013/7316/9759/4609/10014/22938/1387/2033/55294/3066/6233/7311/7314 20 Human_rhinovirus_A_serotype_89 R-HSA-8948751 Regulation of PTEN stability and activity 25/1200 69/10654 4.684012106885404e-8 2.438848497846662e-7 1.1650218875664339e-7 5684/1459/5707/10273/207/1460/7316/1457/8658/4734/5688/10000/5686/5728/2444/5710/8975/5987/208/6233/5716/7311/331/5693/7314 25 Human_rhinovirus_A_serotype_89 R-HSA-179812 GRB2 events in EGFR signaling 10/1200 13/10654 6.592358578129361e-8 3.418054825803207e-7 1.632782310372597e-7 1839/4893/685/2069/1950/6654/2885/1956/3845/3265 10 Human_rhinovirus_A_serotype_89 R-HSA-112399 IRS-mediated signalling 20/1200 48/10654 6.940597176527028e-8 3.583555194909771e-7 1.7118407482295247e-7 5295/5170/4893/5290/3667/5291/2322/2260/5289/10818/2261/2264/208/6654/2885/8660/3845/2549/3265/30849 20 Human_rhinovirus_A_serotype_89 R-HSA-390466 Chaperonin-mediated protein folding 30/1200 95/10654 8.091071006393912e-8 4.16015900912087e-7 1.987280598061663e-7 10694/26224/6000/79861/2629/1459/10575/10382/1460/7277/10576/908/8786/6774/1457/26272/26270/6950/7846/347733/55294/26190/7157/2771/10574/10383/54461/22948/8877/9628 30 Human_rhinovirus_A_serotype_89 R-HSA-8878159 Transcriptional regulation by RUNX3 30/1200 96/10654 1.05203187208605e-7 5.386752407278779e-7 2.5732161972840707e-7 8463/5684/2309/1499/2648/10018/1029/5707/3280/7316/9759/1026/10413/6714/4609/22938/5688/1387/5686/2033/595/5710/7157/6233/5716/7311/3845/5693/7314/4193 30 Human_rhinovirus_A_serotype_89 R-HSA-8934903 Receptor Mediated Mitophagy 9/1200 11/10654 1.2637250563457977e-7 6.443953386490555e-7 3.078234152038481e-7 1459/9140/1460/9474/1457/6714/8408/81631/84557 9 Human_rhinovirus_A_serotype_89 R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 26/1200 77/10654 1.31627341972654e-7 6.6842855964714e-7 3.1930392681258926e-7 5684/79861/51512/5707/63943/10382/7277/7316/983/1026/5688/7846/347733/3320/22919/5686/5710/7157/6233/3326/5716/7311/10383/5347/5693/7314 26 Human_rhinovirus_A_serotype_89 R-HSA-190236 Signaling by FGFR 28/1200 87/10654 1.391485913310191e-7 7.037268922232687e-7 3.3616570813360957e-7 5295/5434/4893/6464/5290/5335/5594/3178/2260/7316/673/6714/10818/2261/867/4670/2264/6654/6233/2885/7311/5518/3845/2549/3265/7314/5595/5515 28 Human_rhinovirus_A_serotype_89 R-HSA-5663220 RHO GTPases Activate Formins 38/1200 140/10654 1.4745829169263355e-7 7.427082936682032e-7 3.547868672303965e-7 11130/81929/79861/54908/71/25936/80776/1783/10382/9212/7277/79980/6232/332/1780/5048/1781/8655/6714/7846/347733/22919/79003/11243/51143/7514/5518/10383/54820/5347/387/23332/9793/10726/140735/5879/5515/1778 38 Human_rhinovirus_A_serotype_89 R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 15/1200 30/10654 1.6423861686084933e-7 8.238636309198702e-7 3.9355423809189396e-7 818/5170/815/4893/817/5594/27330/6195/816/6196/6197/3845/3265/801/5595 15 Human_rhinovirus_A_serotype_89 R-HSA-5654738 Signaling by FGFR2 25/1200 73/10654 1.6760414940622584e-7 8.373421877217923e-7 3.999928560302001e-7 5295/5434/4893/6464/5290/5335/5594/3178/7316/673/6714/10818/867/4670/6654/6233/2885/7311/5518/3845/2549/3265/7314/5595/5515 25 Human_rhinovirus_A_serotype_89 R-HSA-1489509 DAG and IP3 signaling 18/1200 42/10654 1.8770632389822532e-7 9.302393722506429e-7 4.4436923011205316e-7 818/815/5335/5567/817/5578/5582/3708/10645/5566/84254/816/5613/5577/5580/5581/801/814 18 Human_rhinovirus_A_serotype_89 R-HSA-3928662 EPHB-mediated forward signaling 18/1200 42/10654 1.8770632389822532e-7 9.302393722506429e-7 4.4436923011205316e-7 1072/3984/71/5747/3985/2051/6714/4067/2047/2534/9475/8976/7525/6093/387/3265/5058/5879 18 Human_rhinovirus_A_serotype_89 R-HSA-5696394 DNA Damage Recognition in GG-NER 17/1200 38/10654 1.9263020518879472e-7 9.508226928118907e-7 4.542017469714739e-7 10445/8450/7316/10980/4798/1642/10987/1069/6233/7311/8533/8607/5886/50813/7314/51138/8451 17 Human_rhinovirus_A_serotype_89 R-HSA-167044 Signalling to RAS 12/1200 20/10654 2.0991439399942477e-7 1.0320094111366143e-6 4.929841083651828e-7 4893/6464/9261/6714/7867/1432/4914/4803/6654/2885/3845/3265 12 Human_rhinovirus_A_serotype_89 R-HSA-180292 GAB1 signalosome 11/1200 17/10654 2.302671012606937e-7 1.1275777895067303e-6 5.386364941770612e-7 5295/1839/685/5290/2069/1950/6714/2885/1956/2549/5829 11 Human_rhinovirus_A_serotype_89 R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 15/1200 31/10654 2.8518970530516666e-7 1.3910043333856747e-6 6.644736216804382e-7 3725/9252/5594/9261/5598/1432/6195/6196/5518/1386/6197/5599/51231/5595/5515 15 Human_rhinovirus_A_serotype_89 R-HSA-1234174 Cellular response to hypoxia 25/1200 75/10654 3.0370319195339597e-7 1.4754714128759474e-6 7.048229900286023e-7 5684/64344/112399/7321/5707/84962/7422/3091/7316/7322/5688/1387/5686/2033/5710/7428/8453/6233/5716/7311/2034/54583/405/5693/7314 25 Human_rhinovirus_A_serotype_89 R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 17/1200 39/10654 3.0585433358370247e-7 1.4800950887932895e-6 7.070316896052564e-7 10694/26224/2629/10575/10576/908/6774/26272/26270/6950/55294/26190/7157/10574/54461/22948/8877 17 Human_rhinovirus_A_serotype_89 R-HSA-391251 Protein folding 30/1200 101/10654 3.653982838334753e-7 1.7613339150410488e-6 8.413776272481338e-7 10694/26224/6000/79861/2629/1459/10575/10382/1460/7277/10576/908/8786/6774/1457/26272/26270/6950/7846/347733/55294/26190/7157/2771/10574/10383/54461/22948/8877/9628 30 Human_rhinovirus_A_serotype_89 R-HSA-2132295 MHC class II antigen presentation 34/1200 123/10654 4.149315327370987e-7 1.9923171649711275e-6 9.51716806605674e-7 79861/11258/1783/10382/93661/821/55860/830/3123/7277/3126/10671/1780/3115/1781/3122/8655/84516/1639/832/10121/7846/347733/51143/10540/1213/10383/3127/3125/7879/140735/829/51164/1778 34 Human_rhinovirus_A_serotype_89 R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 9/1200 12/10654 4.546971424559493e-7 2.1747917588784548e-6 1.0388837200135927e-6 5295/5290/5291/4067/23533/3717/5294/8660/2549 9 Human_rhinovirus_A_serotype_89 R-HSA-2173789 TGF-beta receptor signaling activates SMADs 15/1200 32/10654 4.811442520702951e-7 2.2924015716399386e-6 1.0950651540717955e-6 10273/4738/7316/23327/867/23645/7046/9040/4087/5499/6233/7514/7048/7311/7314 15 Human_rhinovirus_A_serotype_89 R-HSA-111447 Activation of BAD and translocation to mitochondria 10/1200 15/10654 5.590311659356168e-7 2.6430822174887015e-6 1.2625829922320846e-6 596/7531/572/7532/207/2810/7534/10000/208/7529 10 Human_rhinovirus_A_serotype_89 R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 10/1200 15/10654 5.590311659356168e-7 2.6430822174887015e-6 1.2625829922320846e-6 4615/7316/7335/3654/7189/6233/51135/7311/7334/7314 10 Human_rhinovirus_A_serotype_89 R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 44/1200 182/10654 5.801497554102461e-7 2.7324610617413882e-6 1.3052786783034866e-6 81929/5893/5241/5468/1029/8204/6045/9212/4869/8517/332/3183/5465/5885/4306/5970/4792/3190/9759/8856/6790/641/2099/1387/2908/2033/8243/9126/7022/7428/3066/7157/1107/1069/5987/672/367/7155/25942/9641/6117/4791/10062/4193 44 Human_rhinovirus_A_serotype_89 R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 13/1200 25/10654 6.229711082252922e-7 2.9229899146388236e-6 1.3962930582596102e-6 10694/79861/10575/10382/7277/10576/908/6950/7846/347733/10574/10383/22948 13 Human_rhinovirus_A_serotype_89 R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK 14/1200 29/10654 7.420843115803189e-7 3.4426016559778704e-6 1.6445081697070779e-6 5563/51422/7249/53632/5571/6794/6009/2475/5562/92335/5564/5565/57521/7248 14 Human_rhinovirus_A_serotype_89 R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 14/1200 29/10654 7.420843115803189e-7 3.4426016559778704e-6 1.6445081697070779e-6 11022/5434/8468/91646/122402/56165/55124/84944/3320/54514/54456/143689/9271/136991 14 Human_rhinovirus_A_serotype_89 R-HSA-5654732 Negative regulation of FGFR3 signaling 14/1200 29/10654 7.420843115803189e-7 3.4426016559778704e-6 1.6445081697070779e-6 5594/7316/673/6714/10818/2261/867/6233/2885/7311/5518/7314/5595/5515 14 Human_rhinovirus_A_serotype_89 R-HSA-9022692 Regulation of MECP2 expression and activity 15/1200 33/10654 7.906441257617895e-7 3.6541380194383834e-6 1.745557699296677e-6 818/27161/815/817/9212/192670/5566/3064/816/192669/3066/25942/26523/801/814 15 Human_rhinovirus_A_serotype_89 R-HSA-389357 CD28 dependent PI3K/Akt signaling 12/1200 22/10654 8.680030140291284e-7 3.967095256710906e-6 1.8950553132799686e-6 5295/5170/1326/5290/207/9020/10000/2534/208/2475/3932/253260 12 Human_rhinovirus_A_serotype_89 R-HSA-5205685 Pink/Parkin Mediated Mitophagy 12/1200 22/10654 8.680030140291284e-7 3.967095256710906e-6 1.8950553132799686e-6 65018/9140/8878/10452/9474/7316/81631/6233/9804/7311/84557/7314 12 Human_rhinovirus_A_serotype_89 R-HSA-9613829 Chaperone Mediated Autophagy 12/1200 22/10654 8.680030140291284e-7 3.967095256710906e-6 1.8950553132799686e-6 1915/1080/10013/5116/7316/3920/3320/6233/3326/7311/3312/7314 12 Human_rhinovirus_A_serotype_89 R-HSA-74749 Signal attenuation 8/1200 10/10654 9.258750475099291e-7 4.215977153606098e-6 2.013944558576657e-6 6464/3667/5594/3630/6654/2885/8660/5595 8 Human_rhinovirus_A_serotype_89 R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 21/1200 60/10654 1.0759467359611126e-6 4.8813171771176945e-6 2.331773111990027e-6 8454/1017/1019/5684/5707/1027/6500/7316/5753/1026/5688/6502/5686/595/5710/6233/5716/7311/1163/5693/7314 21 Human_rhinovirus_A_serotype_89 R-HSA-400253 Circadian Clock 23/1200 70/10654 1.1986106896837245e-6 5.4178959379843076e-6 2.588093257076868e-6 8454/26224/8945/8204/1454/4862/6500/3091/1408/6720/5465/406/7316/1387/2908/2033/5499/6233/7311/1386/23411/1453/7314 23 Human_rhinovirus_A_serotype_89 R-HSA-111465 Apoptotic cleavage of cellular proteins 16/1200 38/10654 1.2078222212701408e-6 5.4198277128994684e-6 2.589016053248914e-6 4000/51765/1499/5747/841/7082/660/10134/329/999/5588/836/4137/5580/6709/6093 16 Human_rhinovirus_A_serotype_89 R-HSA-111996 Ca-dependent events 16/1200 38/10654 1.2078222212701408e-6 5.4198277128994684e-6 2.589016053248914e-6 818/815/5567/817/5578/5594/5582/10645/5566/84254/816/5613/5577/5580/801/814 16 Human_rhinovirus_A_serotype_89 R-HSA-6807878 COPI-mediated anterograde transport 29/1200 101/10654 1.2429371907211293e-6 5.557190193296643e-6 2.65463320672705e-6 11014/79861/11258/1783/10382/93661/55860/830/7277/10671/1780/1781/8655/84516/1639/832/10121/8775/7846/347733/51143/3630/10540/6709/10383/140735/829/51164/1778 29 Human_rhinovirus_A_serotype_89 R-HSA-2424491 DAP12 signaling 14/1200 30/10654 1.2476992944598397e-6 5.558342705283185e-6 2.655183754123162e-6 5295/4893/6464/5290/5335/5291/2534/695/6654/2885/3932/3845/3265/5879 14 Human_rhinovirus_A_serotype_89 R-HSA-913531 Interferon Signaling 46/1200 199/10654 1.2604743979239912e-6 5.595055421000738e-6 2.6727211769687054e-6 818/815/81929/6737/51447/5335/23321/4281/7412/10410/2316/817/3123/9636/11274/7706/3126/2634/51127/3115/7316/3122/4734/3434/3659/23586/3717/3458/816/3661/51191/6233/5580/3716/7311/10107/5610/3127/3125/7334/6773/7297/3660/5495/7314/5595 46 Human_rhinovirus_A_serotype_89 R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 9/1200 13/10654 1.3294376449739258e-6 5.842567969216629e-6 2.7909562934072435e-6 7531/7532/2810/7534/983/995/1111/7465/7529 9 Human_rhinovirus_A_serotype_89 R-HSA-141424 Amplification of signal from the kinetochores 28/1200 96/10654 1.3374298719124626e-6 5.842567969216629e-6 2.7909562934072435e-6 11130/81929/54908/25936/80776/1783/9212/79980/6232/332/1780/5048/1781/8655/22919/79003/11243/51143/7514/5518/54820/5347/23332/9793/10726/140735/5515/1778 28 Human_rhinovirus_A_serotype_89 R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 28/1200 96/10654 1.3374298719124626e-6 5.842567969216629e-6 2.7909562934072435e-6 11130/81929/54908/25936/80776/1783/9212/79980/6232/332/1780/5048/1781/8655/22919/79003/11243/51143/7514/5518/54820/5347/23332/9793/10726/140735/5515/1778 28 Human_rhinovirus_A_serotype_89 R-HSA-1433559 Regulation of KIT signaling 10/1200 16/10654 1.339908213361674e-6 5.842567969216629e-6 2.7909562934072435e-6 5578/9306/6714/867/4067/2534/6654/2885/7525/3932 10 Human_rhinovirus_A_serotype_89 R-HSA-9614657 FOXO-mediated transcription of cell death genes 10/1200 16/10654 1.339908213361674e-6 5.842567969216629e-6 2.7909562934072435e-6 2308/2309/65018/10018/356/4303/1387/6794/2033/604 10 Human_rhinovirus_A_serotype_89 R-HSA-76002 Platelet activation, signaling and aggregation 56/1200 262/10654 1.361919127210335e-6 5.917634517526597e-6 2.826815089836129e-6 5295/5170/5590/351/1072/6464/5290/5579/5291/5747/2316/207/3959/7422/5578/5594/5582/7277/3708/5583/7534/1950/308/6714/6647/146850/1432/3920/226/4067/23533/5588/3309/2335/5294/2534/3690/408/55664/2768/87/5894/2771/10487/6654/2885/1398/5580/3932/387/5581/9564/10916/801/5879/5595 56 Human_rhinovirus_A_serotype_89 R-HSA-2990846 SUMOylation 44/1200 188/10654 1.4983302733747017e-6 6.487507218752218e-6 3.0990395312643876e-6 81929/5893/5241/5468/1029/8204/6045/9212/4869/8517/332/3183/5465/5885/4306/5970/4792/3190/9759/8856/6790/641/2099/1387/2908/2033/8243/9126/7022/7428/3066/7157/1107/1069/5987/672/367/7155/25942/9641/6117/4791/10062/4193 44 Human_rhinovirus_A_serotype_89 R-HSA-2682334 EPH-Ephrin signaling 27/1200 92/10654 1.802805848586834e-6 7.77853992012641e-6 3.71575736182785e-6 1072/3984/71/5747/4627/3985/4313/2051/2041/6714/4067/2043/2047/5063/2534/9475/6386/8976/7525/6093/1213/387/3265/5058/5062/1969/5879 27 Human_rhinovirus_A_serotype_89 R-HSA-8986944 Transcriptional Regulation by MECP2 21/1200 62/10654 1.98771054497059e-6 8.546462761302118e-6 4.082589052571173e-6 818/27161/815/5468/6446/817/9212/192670/4233/2289/5566/3064/5728/816/192669/3066/3654/25942/26523/801/814 21 Human_rhinovirus_A_serotype_89 R-HSA-5654733 Negative regulation of FGFR4 signaling 14/1200 31/10654 2.0403542502342963e-6 8.742351197184451e-6 4.1761636700701975e-6 5594/7316/673/6714/10818/867/2264/6233/2885/7311/5518/7314/5595/5515 14 Human_rhinovirus_A_serotype_89 R-HSA-622312 Inflammasomes 11/1200 20/10654 2.2639982831085893e-6 9.667037651750862e-6 4.617880307925004e-6 596/351/4790/10910/29108/5970/598/3326/4210/114548/4791 11 Human_rhinovirus_A_serotype_89 R-HSA-5358351 Signaling by Hedgehog 37/1200 149/10654 2.2963773325310355e-6 9.771481477045855e-6 4.667772436360725e-6 8454/8945/5684/2735/54903/5707/5567/1452/10382/6500/79577/7277/8452/7316/7415/5566/8405/2932/5688/7846/347733/5686/408/5710/83737/5577/6233/5716/7311/51009/10383/23432/23322/8481/5693/5034/7314 37 Human_rhinovirus_A_serotype_89 R-HSA-1236974 ER-Phagosome pathway 25/1200 83/10654 2.5608984738934247e-6 1.0859617583451842e-5 5.187567897921208e-6 23643/1147/8773/5684/5707/811/10333/7099/8517/4615/7316/7096/5688/929/5686/114609/5710/695/6233/5716/7311/7097/3551/5693/7314 25 Human_rhinovirus_A_serotype_89 R-HSA-74752 Signaling by Insulin receptor 24/1200 78/10654 2.6640725524131378e-6 1.1258443594787027e-5 5.378084460531208e-6 5295/5170/4893/6464/5290/3667/5291/5594/2322/2260/5289/10818/2261/2264/3630/208/6654/2885/8660/3845/2549/3265/30849/5595 24 Human_rhinovirus_A_serotype_89 R-HSA-1980143 Signaling by NOTCH1 23/1200 73/10654 2.724701890376589e-6 1.1475365640698672e-5 5.4817066952070765e-6 8454/7090/2648/55869/3280/23220/6500/3091/10013/7316/9759/4609/10014/22938/1387/2033/408/55294/3066/83737/6233/7311/7314 23 Human_rhinovirus_A_serotype_89 R-HSA-111933 Calmodulin induced events 15/1200 36/10654 3.057509130481137e-6 1.2789716159368554e-5 6.109563293735725e-6 818/815/5567/817/5578/5582/10645/5566/84254/816/5613/5577/5580/801/814 15 Human_rhinovirus_A_serotype_89 R-HSA-111997 CaM pathway 15/1200 36/10654 3.057509130481137e-6 1.2789716159368554e-5 6.109563293735725e-6 818/815/5567/817/5578/5582/10645/5566/84254/816/5613/5577/5580/801/814 15 Human_rhinovirus_A_serotype_89 R-HSA-169893 Prolonged ERK activation events 9/1200 14/10654 3.349207793161756e-6 1.3868867170340963e-5 6.625066634300894e-6 5604/5594/673/10818/4914/4803/1398/7529/5595 9 Human_rhinovirus_A_serotype_89 R-HSA-399955 SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion 9/1200 14/10654 3.349207793161756e-6 1.3868867170340963e-5 6.625066634300894e-6 5361/10371/8829/55558/2534/91584/5362/5879/2242 9 Human_rhinovirus_A_serotype_89 R-HSA-9027284 Erythropoietin activates RAS 9/1200 14/10654 3.349207793161756e-6 1.3868867170340963e-5 6.625066634300894e-6 4893/6464/4067/3717/6654/2885/8660/3845/3265 9 Human_rhinovirus_A_serotype_89 R-HSA-5663205 Infectious disease 73/1200 383/10654 3.541758725433261e-6 1.461715808422958e-5 6.982520282494723e-6 3303/8945/81929/5434/1839/5684/8065/6194/6191/5606/5604/1499/1938/3159/6159/6147/6129/6217/5707/8106/6125/4869/821/6500/811/6224/9636/6232/7316/6175/920/292/4233/3055/51534/6714/6210/23327/867/5688/999/3320/5686/2534/5710/5901/6139/5609/6233/2885/3326/5716/7514/1025/9844/7311/3932/1213/5610/3921/6188/6189/6161/3304/6829/801/5608/1022/5062/5693/6122/7314/5879 73 Human_rhinovirus_A_serotype_89 R-HSA-69618 Mitotic Spindle Checkpoint 30/1200 112/10654 3.99577690248205e-6 1.643596232554283e-5 7.851351106631396e-6 11130/81929/54908/25936/80776/1783/7321/9212/79980/6232/332/1780/5048/1781/8655/22919/79003/11243/51143/7514/5518/54820/5347/29882/23332/9793/10726/140735/5515/1778 30 Human_rhinovirus_A_serotype_89 R-HSA-8853659 RET signaling 16/1200 41/10654 4.028902047727744e-6 1.6517159890020055e-5 7.89013864916082e-6 5295/6464/5290/5335/5291/5567/5578/6714/10818/5566/5598/5979/6654/2885/8660/2549 16 Human_rhinovirus_A_serotype_89 R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 20/1200 60/10654 4.600940766072586e-6 1.8799870547462155e-5 8.980574517255657e-6 8454/1147/8945/5684/5707/6500/7316/9020/5970/5688/23291/5686/5710/9040/6233/5716/7311/5693/4791/7314 20 Human_rhinovirus_A_serotype_89 R-HSA-5610787 Hedgehog 'off' state 30/1200 113/10654 4.864250786190008e-6 1.9810183069829934e-5 9.463194164552386e-6 8454/8945/5684/2735/54903/5707/5567/1452/10382/6500/7277/7316/5566/2932/5688/7846/347733/5686/5710/83737/5577/6233/5716/7311/10383/23432/23322/8481/5693/7314 30 Human_rhinovirus_A_serotype_89 R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 12/1200 25/10654 5.049666813843542e-6 2.0430455240271907e-5 9.75949410095732e-6 9252/5594/9261/5598/1432/6195/6196/5518/6197/51231/5595/5515 12 Human_rhinovirus_A_serotype_89 R-HSA-5654708 Downstream signaling of activated FGFR3 12/1200 25/10654 5.049666813843542e-6 2.0430455240271907e-5 9.75949410095732e-6 5295/4893/6464/5290/5335/10818/2261/6654/2885/3845/2549/3265 12 Human_rhinovirus_A_serotype_89 R-HSA-5654726 Negative regulation of FGFR1 signaling 14/1200 33/10654 5.067494514909229e-6 2.043558245554898e-5 9.761943337974435e-6 5594/2260/7316/673/6714/10818/867/6233/2885/7311/5518/7314/5595/5515 14 Human_rhinovirus_A_serotype_89 R-HSA-373760 L1CAM interactions 31/1200 119/10654 5.209585393807073e-6 2.094015757641019e-5 1.0002975554712708e-5 9252/79861/71/5604/1459/10382/5594/1460/7277/2260/8829/1457/6714/27330/7846/347733/3690/6195/6386/6709/3685/6196/1213/10383/1956/6197/3312/5058/8506/5879/5595 31 Human_rhinovirus_A_serotype_89 R-HSA-933541 TRAF6 mediated IRF7 activation 13/1200 29/10654 5.267913454878564e-6 2.110586104974074e-5 1.0082131014121653e-5 7186/29110/57506/7706/23586/1387/2033/64135/3661/7189/10010/84282/9641 13 Human_rhinovirus_A_serotype_89 R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 21/1200 66/10654 6.1729514871483535e-6 2.465185157003582e-5 1.1776027364343647e-5 5684/64344/112399/7321/5707/84962/3091/7316/7322/5688/5686/5710/7428/8453/6233/5716/7311/2034/54583/5693/7314 21 Human_rhinovirus_A_serotype_89 R-HSA-5655302 Signaling by FGFR1 in disease 15/1200 38/10654 6.828980083345648e-6 2.7183746525317838e-5 1.2985496932677631e-5 5295/4893/5290/5335/9530/613/2260/6774/10818/11064/6654/2885/3845/2549/3265 15 Human_rhinovirus_A_serotype_89 R-HSA-75153 Apoptotic execution phase 18/1200 52/10654 7.518766527553397e-6 2.9799805621016597e-5 1.4235171157356729e-5 4000/51765/1499/5747/841/7082/660/3146/10134/329/999/5588/836/4137/5580/6709/6093/5062 18 Human_rhinovirus_A_serotype_89 R-HSA-844456 The NLRP3 inflammasome 9/1200 15/10654 7.534472734000955e-6 2.9799805621016597e-5 1.4235171157356729e-5 351/4790/10910/29108/5970/3326/4210/114548/4791 9 Human_rhinovirus_A_serotype_89 R-HSA-198753 ERK/MAPK targets 11/1200 22/10654 7.673705150062703e-6 3.0061435413261506e-5 1.436014998842143e-5 9252/5594/5598/1432/6195/6196/5518/6197/51231/5595/5515 11 Human_rhinovirus_A_serotype_89 R-HSA-5655332 Signaling by FGFR3 in disease 11/1200 22/10654 7.673705150062703e-6 3.0061435413261506e-5 1.436014998842143e-5 5295/4893/5290/5335/10818/2261/6654/2885/3845/2549/3265 11 Human_rhinovirus_A_serotype_89 R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 11/1200 22/10654 7.673705150062703e-6 3.0061435413261506e-5 1.436014998842143e-5 5295/4893/5290/5335/10818/2261/6654/2885/3845/2549/3265 11 Human_rhinovirus_A_serotype_89 R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission 45/1200 206/10654 8.119662474384955e-6 3.17077958651615e-5 1.5146605548486256e-5 818/5170/5563/815/4893/79861/5579/5567/817/5578/10382/5594/51422/5582/7277/53632/10645/6714/5566/84254/5571/27330/7846/347733/3084/6195/4137/816/2066/5613/2771/5577/6196/5562/10383/6197/3845/3265/5564/801/5565/814/5879/5595/4193 45 Human_rhinovirus_A_serotype_89 R-HSA-111932 CaMK IV-mediated phosphorylation of CREB 8/1200 12/10654 8.264251192620653e-6 3.1968921541360145e-5 1.5271343566631135e-5 818/815/817/10645/84254/816/801/814 8 Human_rhinovirus_A_serotype_89 R-HSA-170968 Frs2-mediated activation 8/1200 12/10654 8.264251192620653e-6 3.1968921541360145e-5 1.5271343566631135e-5 5604/5594/673/10818/4914/4803/7529/5595 8 Human_rhinovirus_A_serotype_89 R-HSA-210990 PECAM1 interactions 8/1200 12/10654 8.264251192620653e-6 3.1968921541360145e-5 1.5271343566631135e-5 5335/6714/4067/2534/3690/7525/3685/3932 8 Human_rhinovirus_A_serotype_89 R-HSA-2173788 Downregulation of TGF-beta receptor signaling 12/1200 26/10654 8.419888511092993e-6 3.2469195070902354e-5 1.551032094148709e-5 10273/7316/23327/23645/7046/4087/5499/6233/7514/7048/7311/7314 12 Human_rhinovirus_A_serotype_89 R-HSA-8939902 Regulation of RUNX2 expression and activity 22/1200 73/10654 1.0026893862219057e-5 3.854575397501033e-5 1.8413053165576886e-5 8454/7291/5684/5707/10273/6500/7316/11059/2099/2932/5688/6502/2908/5686/55294/5710/6233/5716/7311/1750/5693/7314 22 Human_rhinovirus_A_serotype_89 R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 24/1200 84/10654 1.1099002929484786e-5 4.253468824529263e-5 2.0318540832008763e-5 6118/10445/7515/8450/54778/7316/10980/6119/4798/1642/10987/1069/6233/7311/8533/8607/6117/7334/1022/5886/50813/7314/51138/8451 24 Human_rhinovirus_A_serotype_89 R-HSA-6804760 Regulation of TP53 Activity through Methylation 10/1200 19/10654 1.123076490743619e-5 4.290638977020514e-5 2.0496100205847372e-5 7316/4194/56950/2033/7157/6233/7311/10419/7314/4193 10 Human_rhinovirus_A_serotype_89 R-HSA-109704 PI3K Cascade 16/1200 44/10654 1.1728043984010123e-5 4.466792060576695e-5 2.1337571900733167e-5 5295/5170/5290/3667/5291/2322/2260/5289/10818/2261/2264/208/2885/8660/2549/30849 16 Human_rhinovirus_A_serotype_89 R-HSA-199977 ER to Golgi Anterograde Transport 36/1200 154/10654 1.3577692281471124e-5 5.1354844920006705e-5 2.4531871666982642e-5 10113/11014/79861/11258/55291/1783/10382/93661/55860/830/7277/10671/1780/1781/8655/84516/1639/832/3998/10121/8775/55014/7846/347733/51143/3630/10540/6709/83696/5537/10383/1453/140735/829/51164/1778 36 Human_rhinovirus_A_serotype_89 R-HSA-5654716 Downstream signaling of activated FGFR4 12/1200 27/10654 1.3608617738121712e-5 5.1354844920006705e-5 2.4531871666982642e-5 5295/4893/6464/5290/5335/10818/2264/6654/2885/3845/2549/3265 12 Human_rhinovirus_A_serotype_89 R-HSA-912526 Interleukin receptor SHC signaling 12/1200 27/10654 1.3608617738121712e-5 5.1354844920006705e-5 2.4531871666982642e-5 5295/6464/5290/1437/5291/1439/1438/3558/3717/6654/2885/3716 12 Human_rhinovirus_A_serotype_89 R-HSA-112043 PLC beta mediated events 18/1200 54/10654 1.3705861358526047e-5 5.1564124745186406e-5 2.4631843263076332e-5 818/815/5567/817/5578/5594/5582/3708/10645/5566/84254/816/5613/2771/5577/5580/801/814 18 Human_rhinovirus_A_serotype_89 R-HSA-5676590 NIK-->noncanonical NF-kB signaling 19/1200 59/10654 1.3967097638629751e-5 5.2387229440939546e-5 2.5025034962830457e-5 8454/1147/8945/5684/5707/6500/7316/9020/5688/23291/5686/5710/9040/6233/5716/7311/5693/4791/7314 19 Human_rhinovirus_A_serotype_89 R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 27/1200 102/10654 1.5180553950053975e-5 5.676607143747456e-5 2.7116778985742345e-5 8454/7124/1147/8945/5684/7186/5707/356/6500/330/7316/9020/7132/5688/329/23291/5686/5710/9040/6233/5716/7311/7187/958/5693/4791/7314 27 Human_rhinovirus_A_serotype_89 R-HSA-205043 NRIF signals cell death from the nucleus 9/1200 16/10654 1.549891283196578e-5 5.760740492363185e-5 2.751867845878515e-5 4804/8878/7316/4803/7189/6233/7311/5599/7314 9 Human_rhinovirus_A_serotype_89 R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 9/1200 16/10654 1.549891283196578e-5 5.760740492363185e-5 2.751867845878515e-5 5295/5170/6464/5290/5291/4067/2534/6654/2885 9 Human_rhinovirus_A_serotype_89 R-HSA-376176 Signaling by ROBO receptors 46/1200 218/10654 1.6757496914457152e-5 6.209835192924963e-5 2.966397430724199e-5 25/23032/5684/6194/6191/6159/6147/6129/6217/5707/5567/56924/5578/6125/6224/6232/2935/8829/7316/6175/6714/6210/5566/5688/5686/5063/5710/8453/6139/10487/6654/6233/5716/7311/387/3921/6188/6189/6161/23332/5058/5062/5693/6122/7314/5879 46 Human_rhinovirus_A_serotype_89 R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 24/1200 86/10654 1.7178553853714082e-5 6.327861329994978e-5 3.0227777401664995e-5 8454/1017/8945/5684/7321/5707/9212/6500/7316/983/6790/5688/6502/5686/5710/4751/6233/5716/51343/7311/5347/29882/5693/7314 24 Human_rhinovirus_A_serotype_89 R-HSA-453276 Regulation of mitotic cell cycle 24/1200 86/10654 1.7178553853714082e-5 6.327861329994978e-5 3.0227777401664995e-5 8454/1017/8945/5684/7321/5707/9212/6500/7316/983/6790/5688/6502/5686/5710/4751/6233/5716/51343/7311/5347/29882/5693/7314 24 Human_rhinovirus_A_serotype_89 R-HSA-69481 G2/M Checkpoints 38/1200 168/10654 1.7673784308423862e-5 6.490907689462811e-5 3.100663913758572e-5 1017/4172/6118/5684/5883/7531/51512/5707/7532/2810/545/7534/7316/4174/983/641/4171/6119/3364/10524/5688/5686/995/5710/1111/7157/6233/5716/672/7311/9025/6117/7334/7465/5810/5693/7529/7314 38 Human_rhinovirus_A_serotype_89 R-HSA-112040 G-protein mediated events 18/1200 55/10654 1.8252744454789997e-5 6.683645892347434e-5 3.19273368567309e-5 818/815/5567/817/5578/5594/5582/3708/10645/5566/84254/816/5613/2771/5577/5580/801/814 18 Human_rhinovirus_A_serotype_89 R-HSA-877300 Interferon gamma signaling 25/1200 92/10654 1.9108253318080932e-5 6.976208459914755e-5 3.332488900070172e-5 818/815/6737/23321/4281/7412/817/3123/7706/3126/2634/51127/3115/3122/3659/3717/3458/816/3661/5580/3716/10107/3127/3125/3660 25 Human_rhinovirus_A_serotype_89 R-HSA-1251985 Nuclear signaling by ERBB4 13/1200 32/10654 1.9489622311046315e-5 7.052842795258403e-5 3.369096618054001e-5 1839/685/5241/2069/23118/10413/6714/2099/145957/3084/2066/9542/10718 13 Human_rhinovirus_A_serotype_89 R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 13/1200 32/10654 1.9489622311046315e-5 7.052842795258403e-5 3.369096618054001e-5 54778/7316/6667/4609/22938/1874/4087/6233/1025/1030/7311/23439/7314 13 Human_rhinovirus_A_serotype_89 R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 13/1200 32/10654 1.9489622311046315e-5 7.052842795258403e-5 3.369096618054001e-5 10694/79861/10575/10382/7277/10576/908/6950/7846/347733/10574/10383/22948 13 Human_rhinovirus_A_serotype_89 R-HSA-110056 MAPK3 (ERK1) activation 7/1200 10/10654 1.9947736027048734e-5 7.155670423656436e-5 3.4182166998614724e-5 5604/983/3717/3716/7297/3569/5595 7 Human_rhinovirus_A_serotype_89 R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 7/1200 10/10654 1.9947736027048734e-5 7.155670423656436e-5 3.4182166998614724e-5 5563/51422/53632/1432/5571/5564/5565 7 Human_rhinovirus_A_serotype_89 R-HSA-390450 Folding of actin by CCT/TriC 7/1200 10/10654 1.9947736027048734e-5 7.155670423656436e-5 3.4182166998614724e-5 10694/10575/10576/908/6950/10574/22948 7 Human_rhinovirus_A_serotype_89 R-HSA-8876384 Listeria monocytogenes entry into host cells 10/1200 20/10654 2.019753153176373e-5 7.224276495709114e-5 3.450989369271606e-5 1499/7316/4233/6714/867/999/6233/2885/7311/7314 10 Human_rhinovirus_A_serotype_89 R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 12/1200 28/10654 2.1385760921145706e-5 7.627176004824797e-5 3.643451814980711e-5 10694/10575/10382/7277/10576/908/6950/7846/347733/10574/10383/22948 12 Human_rhinovirus_A_serotype_89 R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 11/1200 24/10654 2.1921297087381072e-5 7.795642825887102e-5 3.723927307427089e-5 5590/5579/5578/5594/5289/6279/1432/5580/30849/5879/5595 11 Human_rhinovirus_A_serotype_89 R-HSA-1236975 Antigen processing-Cross presentation 26/1200 99/10654 2.5238777879552514e-5 8.949612615910288e-5 4.275171086675562e-5 23643/1147/8773/5684/5707/811/10333/7099/8517/4615/7316/7096/5688/929/5686/114609/5710/695/6233/5716/3685/7311/7097/3551/5693/7314 26 Human_rhinovirus_A_serotype_89 R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 24/1200 88/10654 2.6123238958000414e-5 9.236698244748571e-5 4.4123100034625946e-5 3303/5684/5707/207/5578/3315/7534/7316/9261/1432/5688/5686/5710/6233/5580/5716/7514/7311/3304/3312/5693/7529/7314/1994 24 Human_rhinovirus_A_serotype_89 R-HSA-5696398 Nucleotide Excision Repair 28/1200 111/10654 2.800107354220567e-5 9.872378500309085e-5 4.7159702807925335e-5 10450/6118/5434/27339/10445/7515/8450/54778/7316/10980/6119/4798/1642/2033/10987/1069/6233/7311/8533/8607/6117/7334/1022/5886/50813/7314/51138/8451 28 Human_rhinovirus_A_serotype_89 R-HSA-202433 Generation of second messenger molecules 13/1200 33/10654 2.8864005378535477e-5 1.0147630380943811e-4 4.847456293891098e-5 5335/3123/3126/3115/3122/920/5063/3702/3932/3127/3125/5058/5062 13 Human_rhinovirus_A_serotype_89 R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 12/1200 29/10654 3.2763065014981366e-5 1.14856881330929e-4 5.486637681934678e-5 2308/2309/4303/4287/6720/847/2908/3630/3066/4087/91584/25942 12 Human_rhinovirus_A_serotype_89 R-HSA-389513 CTLA4 inhibitory signaling 10/1200 21/10654 3.467632921332537e-5 1.2121980240578897e-4 5.7905902369053844e-5 207/6714/4067/10000/2534/208/7525/3932/5518/5515 10 Human_rhinovirus_A_serotype_89 R-HSA-5696395 Formation of Incision Complex in GG-NER 15/1200 43/10654 3.8786902207969985e-5 1.3520632012608747e-4 6.458716989730358e-5 6118/8450/54778/7316/6119/1642/1069/6233/7311/6117/7334/1022/5886/7314/8451 15 Human_rhinovirus_A_serotype_89 R-HSA-6806834 Signaling by MET 22/1200 79/10654 3.9524518273681577e-5 1.3738945225274103e-4 6.563003775615028e-5 5295/4893/6464/5290/5747/7316/6774/4233/6714/3910/867/2335/6654/6233/2885/1398/7311/3845/2549/3265/7314/5879 22 Human_rhinovirus_A_serotype_89 R-HSA-73893 DNA Damage Bypass 16/1200 48/10654 4.098875237227737e-5 1.3979623273384785e-4 6.677974096302549e-5 6118/9636/7706/8450/7316/9100/7415/6119/51455/1642/5429/6233/7311/6117/7314/8451 16 Human_rhinovirus_A_serotype_89 R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 18/1200 58/10654 4.10033506030119e-5 1.3979623273384785e-4 6.677974096302549e-5 8454/2648/55869/3280/6500/10013/7316/9759/4609/10014/22938/1387/2033/55294/3066/6233/7311/7314 18 Human_rhinovirus_A_serotype_89 R-HSA-2644603 Signaling by NOTCH1 in Cancer 18/1200 58/10654 4.10033506030119e-5 1.3979623273384785e-4 6.677974096302549e-5 8454/2648/55869/3280/6500/10013/7316/9759/4609/10014/22938/1387/2033/55294/3066/6233/7311/7314 18 Human_rhinovirus_A_serotype_89 R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 18/1200 58/10654 4.10033506030119e-5 1.3979623273384785e-4 6.677974096302549e-5 8454/2648/55869/3280/6500/10013/7316/9759/4609/10014/22938/1387/2033/55294/3066/6233/7311/7314 18 Human_rhinovirus_A_serotype_89 R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 18/1200 58/10654 4.10033506030119e-5 1.3979623273384785e-4 6.677974096302549e-5 8454/2648/55869/3280/6500/10013/7316/9759/4609/10014/22938/1387/2033/55294/3066/6233/7311/7314 18 Human_rhinovirus_A_serotype_89 R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 18/1200 58/10654 4.10033506030119e-5 1.3979623273384785e-4 6.677974096302549e-5 8454/2648/55869/3280/6500/10013/7316/9759/4609/10014/22938/1387/2033/55294/3066/6233/7311/7314 18 Human_rhinovirus_A_serotype_89 R-HSA-2559580 Oxidative Stress Induced Senescence 30/1200 125/10654 4.1009915923543695e-5 1.3979623273384785e-4 6.677974096302549e-5 3725/1019/5606/9448/1029/2146/6045/5594/50488/192670/7316/9261/7867/4194/1432/1021/192669/7157/5609/6233/1030/7311/5599/4217/26523/5608/7314/5595/4193/23043 30 Human_rhinovirus_A_serotype_89 R-HSA-5654727 Negative regulation of FGFR2 signaling 13/1200 34/10654 4.194882693751721e-5 1.4260289928621554e-4 6.81204671161654e-5 5594/7316/673/6714/10818/867/6233/2885/7311/5518/7314/5595/5515 13 Human_rhinovirus_A_serotype_89 R-HSA-73894 DNA Repair 62/1200 334/10654 4.403528513515579e-5 1.4928445565050066e-4 7.131220264802558e-5 10450/1017/7014/6118/2176/25/25913/5434/5893/151987/5888/5883/328/27339/10445/7515/7013/5531/9636/545/7706/5591/8450/54778/7316/641/9100/7415/10980/6119/51455/3364/10524/4798/1642/5429/2033/1111/10987/7157/1069/4255/6233/672/7311/6047/9025/2189/5536/8533/8607/6117/2175/5599/7334/5810/1022/5886/50813/7314/51138/8451 62 Human_rhinovirus_A_serotype_89 R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 7/1200 11/10654 4.9504980879156766e-5 1.6645543979531185e-4 7.951466884361906e-5 64344/7422/3091/1387/2033/2034/405 7 Human_rhinovirus_A_serotype_89 R-HSA-8851805 MET activates RAS signaling 7/1200 11/10654 4.9504980879156766e-5 1.6645543979531185e-4 7.951466884361906e-5 4893/6464/4233/6654/2885/3845/3265 7 Human_rhinovirus_A_serotype_89 R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 7/1200 11/10654 4.9504980879156766e-5 1.6645543979531185e-4 7.951466884361906e-5 4893/4915/10818/6654/2885/3845/3265 7 Human_rhinovirus_A_serotype_89 R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 15/1200 44/10654 5.278286335829442e-5 1.765150498215049e-4 8.432007839293932e-5 7321/54778/7316/6667/4609/22938/23327/1874/4087/6233/1025/1030/7311/23439/7314 15 Human_rhinovirus_A_serotype_89 R-HSA-451927 Interleukin-2 family signaling 15/1200 44/10654 5.278286335829442e-5 1.765150498215049e-4 8.432007839293932e-5 5295/6464/5290/1437/5291/1439/1438/6774/3558/3717/6654/2885/3716/3932/2185 15 Human_rhinovirus_A_serotype_89 R-HSA-111471 Apoptotic factor-mediated response 9/1200 18/10654 5.337207165971142e-5 1.7752327878189727e-4 8.480170273638357e-5 1029/842/5594/54205/836/331/317/578/5595 9 Human_rhinovirus_A_serotype_89 R-HSA-210993 Tie2 Signaling 9/1200 18/10654 5.337207165971142e-5 1.7752327878189727e-4 8.480170273638357e-5 5295/4893/6464/5290/5291/6654/2885/3845/3265 9 Human_rhinovirus_A_serotype_89 R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 17/1200 54/10654 5.4447163827164144e-5 1.8061236602881872e-4 8.627733939788318e-5 10450/5434/27339/8450/7316/10980/1642/2033/10987/6233/7311/8533/1022/50813/7314/51138/8451 17 Human_rhinovirus_A_serotype_89 R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 10/1200 22/10654 5.7178515932710854e-5 1.8865852583145772e-4 9.012093701750093e-5 4000/3725/351/2309/10018/7531/356/995/8851/1020 10 Human_rhinovirus_A_serotype_89 R-HSA-8863678 Neurodegenerative Diseases 10/1200 22/10654 5.7178515932710854e-5 1.8865852583145772e-4 9.012093701750093e-5 4000/3725/351/2309/10018/7531/356/995/8851/1020 10 Human_rhinovirus_A_serotype_89 R-HSA-114604 GPVI-mediated activation cascade 13/1200 35/10654 5.991060634189908e-5 1.971458352690759e-4 9.417526891638872e-5 5295/5170/5590/5290/5291/146850/4067/23533/5294/2534/3932/387/5879 13 Human_rhinovirus_A_serotype_89 R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 27/1200 110/10654 6.470076628727967e-5 2.123424085066572e-4 1.014345720069334e-4 1017/3725/1019/4790/1029/7321/5594/1027/3576/3490/7316/6774/5970/1026/5598/1021/6195/6233/1030/51343/6196/7311/6197/29882/3569/7314/5595 27 Human_rhinovirus_A_serotype_89 R-HSA-5610780 Degradation of GLI1 by the proteasome 18/1200 60/10654 6.768667362207819e-5 2.203835230861332e-4 1.0527575955662763e-4 8454/8945/5684/2735/5707/5567/6500/7316/5566/5688/5686/5710/83737/6233/5716/7311/5693/7314 18 Human_rhinovirus_A_serotype_89 R-HSA-5610783 Degradation of GLI2 by the proteasome 18/1200 60/10654 6.768667362207819e-5 2.203835230861332e-4 1.0527575955662763e-4 8454/8945/5684/5707/5567/1452/6500/7316/5566/2932/5688/5686/5710/6233/5716/7311/5693/7314 18 Human_rhinovirus_A_serotype_89 R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 18/1200 60/10654 6.768667362207819e-5 2.203835230861332e-4 1.0527575955662763e-4 8454/8945/5684/5707/5567/1452/6500/7316/5566/2932/5688/5686/5710/6233/5716/7311/5693/7314 18 Human_rhinovirus_A_serotype_89 R-HSA-156842 Eukaryotic Translation Elongation 24/1200 93/10654 6.937734972292958e-5 2.2529381462656607e-4 1.0762137353141431e-4 6194/6191/1938/6159/6147/6129/1915/6217/1936/6125/1937/6224/6232/6175/1933/6210/6139/6233/7311/3921/6188/6189/6161/6122 24 Human_rhinovirus_A_serotype_89 R-HSA-5654687 Downstream signaling of activated FGFR1 12/1200 31/10654 7.187530041651238e-5 2.3279296775321857e-4 1.1120366965947487e-4 5295/4893/6464/5290/5335/2260/10818/6654/2885/3845/2549/3265 12 Human_rhinovirus_A_serotype_89 R-HSA-9013694 Signaling by NOTCH4 22/1200 82/10654 7.341348444299043e-5 2.3715246021636173e-4 1.1328617053754379e-4 8454/5684/2648/5707/207/3280/6500/7534/7316/22938/5688/1387/5686/2033/55294/5710/6233/2324/5716/7311/5693/7314 22 Human_rhinovirus_A_serotype_89 R-HSA-354192 Integrin alphaIIb beta3 signaling 11/1200 27/10654 8.311887897108725e-5 2.6710598086021267e-4 1.2759477035035322e-4 5170/6464/5747/207/6714/2335/3690/6654/2885/1398/9564 11 Human_rhinovirus_A_serotype_89 R-HSA-9006921 Integrin signaling 11/1200 27/10654 8.311887897108725e-5 2.6710598086021267e-4 1.2759477035035322e-4 5170/6464/5747/207/6714/2335/3690/6654/2885/1398/9564 11 Human_rhinovirus_A_serotype_89 R-HSA-110320 Translesion Synthesis by POLH 9/1200 19/10654 9.129924773675949e-5 2.911195651347835e-4 1.3906590162541903e-4 6118/7316/7415/6119/5429/6233/7311/6117/7314 9 Human_rhinovirus_A_serotype_89 R-HSA-3928664 Ephrin signaling 9/1200 19/10654 9.129924773675949e-5 2.911195651347835e-4 1.3906590162541903e-4 2051/6714/2047/5063/2534/6386/5058/5062/5879 9 Human_rhinovirus_A_serotype_89 R-HSA-5686938 Regulation of TLR by endogenous ligand 9/1200 19/10654 9.129924773675949e-5 2.911195651347835e-4 1.3906590162541903e-4 23643/6271/10333/7099/7096/6279/3146/929/7097 9 Human_rhinovirus_A_serotype_89 R-HSA-202733 Cell surface interactions at the vascular wall 31/1200 137/10654 1.0138648894727021e-4 3.224508437137408e-4 1.5403264734257003e-4 5295/4893/6464/857/5290/5335/5291/483/10461/482/2994/6714/8797/4067/682/2335/2534/3690/23759/6654/4099/2885/7525/3685/3932/3845/4282/3265/8795/481/5669 31 Human_rhinovirus_A_serotype_89 R-HSA-5656169 Termination of translesion DNA synthesis 12/1200 32/10654 1.0330670727979166e-4 3.277133079261257e-4 1.5654649188657374e-4 6118/9636/7706/7316/9100/6119/51455/5429/6233/7311/6117/7314 12 Human_rhinovirus_A_serotype_89 R-HSA-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation 7/1200 12/10654 1.0724200244030711e-4 3.3673443005429767e-4 1.6085582259695185e-4 6697/2643/207/3320/4846/5593/801 7 Human_rhinovirus_A_serotype_89 R-HSA-389359 CD28 dependent Vav1 pathway 7/1200 12/10654 1.0724200244030711e-4 3.3673443005429767e-4 1.6085582259695185e-4 5063/2534/2885/3932/5058/5062/5879 7 Human_rhinovirus_A_serotype_89 R-HSA-5689877 Josephin domain DUBs 7/1200 12/10654 1.0724200244030711e-4 3.3673443005429767e-4 1.6085582259695185e-4 4287/7316/7415/6233/7311/5886/7314 7 Human_rhinovirus_A_serotype_89 R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 7/1200 12/10654 1.0724200244030711e-4 3.3673443005429767e-4 1.6085582259695185e-4 355/8797/7157/8626/7161/7159/8795 7 Human_rhinovirus_A_serotype_89 R-HSA-176187 Activation of ATR in response to replication stress 13/1200 37/10654 1.1653408945748781e-4 3.640583959254176e-4 1.7390830138892252e-4 1017/4172/6118/5883/545/4174/4171/6119/3364/995/1111/6117/5810 13 Human_rhinovirus_A_serotype_89 R-HSA-5685938 HDR through Single Strand Annealing (SSA) 13/1200 37/10654 1.1653408945748781e-4 3.640583959254176e-4 1.7390830138892252e-4 6118/25/5893/5888/5883/545/641/6119/3364/10524/672/6117/5810 13 Human_rhinovirus_A_serotype_89 R-HSA-383280 Nuclear Receptor transcription pathway 16/1200 52/10654 1.21791045664765e-4 3.7952058169272735e-4 1.81294485838034e-4 5241/7182/5468/5465/2100/4306/9970/8856/2099/5467/2908/3164/2103/29982/367/10062 16 Human_rhinovirus_A_serotype_89 R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 21/1200 79/10654 1.2279766492131284e-4 3.8169349751360215e-4 1.82332473434801e-4 10450/6118/5434/27339/7515/8450/7316/10980/6119/1642/2033/10987/6233/7311/8533/6117/1022/50813/7314/51138/8451 21 Human_rhinovirus_A_serotype_89 R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 14/1200 42/10654 1.2323772712691998e-4 3.8209888259954584e-4 1.8252612322421368e-4 10694/6000/1459/10575/1460/10576/908/8786/1457/6950/2771/10574/22948/9628 14 Human_rhinovirus_A_serotype_89 R-HSA-69615 G1/S DNA Damage Checkpoints 19/1200 68/10654 1.2450724398459587e-4 3.8425308612227e-4 1.8355517207922138e-4 1017/5684/1029/5707/1027/7316/1026/4194/5688/5686/5710/1111/7157/6233/5716/7311/5693/7314/4193 19 Human_rhinovirus_A_serotype_89 R-HSA-437239 Recycling pathway of L1 15/1200 47/10654 1.2455529533947164e-4 3.8425308612227e-4 1.8355517207922138e-4 9252/79861/71/10382/5594/7277/6714/27330/7846/347733/6195/6196/1213/10383/6197 15 Human_rhinovirus_A_serotype_89 R-HSA-1226099 Signaling by FGFR in disease 18/1200 63/10654 1.363549054043118e-4 4.196058685010492e-4 2.0044296371286152e-4 5295/5434/4893/5290/5335/9530/613/2260/6774/10818/2261/11064/2264/6654/2885/3845/2549/3265 18 Human_rhinovirus_A_serotype_89 R-HSA-8940973 RUNX2 regulates osteoblast differentiation 10/1200 24/10654 1.4033664690039116e-4 4.307846325250813e-4 2.0578298576648087e-4 25/5594/3280/5925/10013/10413/6714/7525/367/5595 10 Human_rhinovirus_A_serotype_89 R-HSA-110312 Translesion synthesis by REV1 8/1200 16/10654 1.4174063364651892e-4 4.329404502965454e-4 2.0681280573749502e-4 6118/7316/6119/51455/6233/7311/6117/7314 8 Human_rhinovirus_A_serotype_89 R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 8/1200 16/10654 1.4174063364651892e-4 4.329404502965454e-4 2.0681280573749502e-4 5590/7316/7046/6233/7048/7311/387/7314 8 Human_rhinovirus_A_serotype_89 R-HSA-2172127 DAP12 interactions 14/1200 43/10654 1.6400709088089675e-4 4.997154324617941e-4 2.3871077555114273e-4 5295/4893/6464/5290/5335/5291/2534/695/6654/2885/3932/3845/3265/5879 14 Human_rhinovirus_A_serotype_89 R-HSA-9604323 Negative regulation of NOTCH4 signaling 16/1200 54/10654 1.994114768361847e-4 6.060930108764825e-4 2.8952664513420644e-4 8454/5684/5707/207/6500/7534/7316/5688/5686/55294/5710/6233/5716/7311/5693/7314 16 Human_rhinovirus_A_serotype_89 R-HSA-111461 Cytochrome c-mediated apoptotic response 7/1200 13/10654 2.0977106027366766e-4 6.32903394566518e-4 3.0233378909600794e-4 842/5594/54205/836/331/317/5595 7 Human_rhinovirus_A_serotype_89 R-HSA-171007 p38MAPK events 7/1200 13/10654 2.0977106027366766e-4 6.32903394566518e-4 3.0233378909600794e-4 4893/9261/6714/7867/1432/3845/3265 7 Human_rhinovirus_A_serotype_89 R-HSA-879415 Advanced glycosylation endproduct receptor signaling 7/1200 13/10654 2.0977106027366766e-4 6.32903394566518e-4 3.0233378909600794e-4 351/1650/5594/830/3146/829/5595 7 Human_rhinovirus_A_serotype_89 R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 10/1200 25/10654 2.104426928229265e-4 6.333811779109544e-4 3.0256202305735256e-4 1017/2305/983/995/7514/5518/5347/7465/1022/5515 10 Human_rhinovirus_A_serotype_89 R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 13/1200 39/10654 2.1424889887914473e-4 6.432679834960209e-4 3.0728488506164947e-4 6118/9636/7706/7316/9100/7415/6119/51455/5429/6233/7311/6117/7314 13 Human_rhinovirus_A_serotype_89 R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 14/1200 44/10654 2.1591173039144432e-4 6.466870759782579e-4 3.08918163053676e-4 355/332/8797/1387/843/7157/8626/604/7161/7159/317/10397/8795/665 14 Human_rhinovirus_A_serotype_89 R-HSA-5655862 Translesion synthesis by POLK 8/1200 17/10654 2.413816935628991e-4 7.177470117026927e-4 3.4286302700120097e-4 6118/7316/6119/51455/6233/7311/6117/7314 8 Human_rhinovirus_A_serotype_89 R-HSA-5656121 Translesion synthesis by POLI 8/1200 17/10654 2.413816935628991e-4 7.177470117026927e-4 3.4286302700120097e-4 6118/7316/6119/51455/6233/7311/6117/7314 8 Human_rhinovirus_A_serotype_89 R-HSA-8934593 Regulation of RUNX1 Expression and Activity 8/1200 17/10654 2.413816935628991e-4 7.177470117026927e-4 3.4286302700120097e-4 27161/894/192670/6714/1021/595/192669/26523 8 Human_rhinovirus_A_serotype_89 R-HSA-3928663 EPHA-mediated growth cone collapse 11/1200 30/10654 2.53049957953948e-4 7.488336885255918e-4 3.5771292806818344e-4 4627/2041/6714/4067/2043/2534/9475/7525/6093/387/1969 11 Human_rhinovirus_A_serotype_89 R-HSA-5654696 Downstream signaling of activated FGFR2 11/1200 30/10654 2.53049957953948e-4 7.488336885255918e-4 3.5771292806818344e-4 5295/4893/6464/5290/5335/10818/6654/2885/3845/2549/3265 11 Human_rhinovirus_A_serotype_89 R-HSA-69563 p53-Dependent G1 DNA Damage Response 18/1200 66/10654 2.598129257177934e-4 7.651769697750764e-4 3.655200060343281e-4 1017/5684/1029/5707/1027/7316/1026/4194/5688/5686/5710/7157/6233/5716/7311/5693/7314/4193 18 Human_rhinovirus_A_serotype_89 R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 18/1200 66/10654 2.598129257177934e-4 7.651769697750764e-4 3.655200060343281e-4 1017/5684/1029/5707/1027/7316/1026/4194/5688/5686/5710/7157/6233/5716/7311/5693/7314/4193 18 Human_rhinovirus_A_serotype_89 R-HSA-1169408 ISG15 antiviral mechanism 19/1200 72/10654 2.820968588114433e-4 8.268615342300816e-4 3.949863167865271e-4 81929/5335/9636/11274/7706/7316/4734/3434/23586/3661/51191/6233/3716/7311/5610/7334/5495/7314/5595 19 Human_rhinovirus_A_serotype_89 R-HSA-442729 CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde 6/1200 10/10654 2.8343794892976055e-4 8.268615342300816e-4 3.949863167865271e-4 818/10645/84254/816/801/814 6 Human_rhinovirus_A_serotype_89 R-HSA-450341 Activation of the AP-1 family of transcription factors 6/1200 10/10654 2.8343794892976055e-4 8.268615342300816e-4 3.949863167865271e-4 3725/5594/1432/1386/5599/5595 6 Human_rhinovirus_A_serotype_89 R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 6/1200 10/10654 2.8343794892976055e-4 8.268615342300816e-4 3.949863167865271e-4 2308/2309/4303/1387/2033/23411 6 Human_rhinovirus_A_serotype_89 R-HSA-182971 EGFR downregulation 11/1200 31/10654 3.526960195995386e-4 0.0010264785098722422 4.903420332069057e-4 1839/685/2069/7316/1950/867/6233/2885/7311/1956/7314 11 Human_rhinovirus_A_serotype_89 R-HSA-8854214 TBC/RABGAPs 14/1200 46/10654 3.630801925228447e-4 0.0010542140178192714 5.035911029419022e-4 5868/9363/11337/51256/7249/8766/8408/81631/10133/11345/338382/4218/7248/7879 14 Human_rhinovirus_A_serotype_89 R-HSA-111885 Opioid Signalling 22/1200 91/10654 3.7615992924586866e-4 0.0010896275884727743 5.205079327345848e-4 818/815/5567/817/5578/5594/5582/3708/10645/5566/84254/816/5613/5499/2771/5577/5580/5518/801/1020/814/5515 22 Human_rhinovirus_A_serotype_89 R-HSA-195721 Signaling by WNT 58/1200 331/10654 3.786557945522604e-4 0.0010897011243606145 5.20543060344574e-4 8454/27161/8945/815/5684/857/7015/7090/6885/5579/1499/1459/5707/207/1454/1452/5578/5582/6500/79577/1460/3708/192670/7534/8452/7316/1457/8658/4609/2932/10524/5688/1387/51339/5686/2033/5710/192669/208/23513/6233/5716/7514/7311/5518/1213/387/331/8607/5593/3845/26523/801/5693/4920/7314/5879/5515 58 Human_rhinovirus_A_serotype_89 R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 7/1200 14/10654 3.788345075775556e-4 0.0010897011243606145 5.20543060344574e-4 332/7157/8626/604/7161/7159/10397 7 Human_rhinovirus_A_serotype_89 R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 7/1200 14/10654 3.788345075775556e-4 0.0010897011243606145 5.20543060344574e-4 207/10000/7157/8626/208/7161/7159 7 Human_rhinovirus_A_serotype_89 R-HSA-447115 Interleukin-12 family signaling 16/1200 57/10654 3.950541100576103e-4 0.001133713422816491 5.4156744585621e-4 1072/9049/821/3313/6175/6774/6647/6950/3717/3458/3716/4282/7297/5062/5034/829 16 Human_rhinovirus_A_serotype_89 R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 20/1200 80/10654 4.287013683376792e-4 0.0012245775197423522 5.849726273613556e-4 81929/5335/2316/9636/11274/7706/7316/4734/3434/23586/3661/51191/6233/3716/7311/5610/7334/5495/7314/5595 20 Human_rhinovirus_A_serotype_89 R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 20/1200 80/10654 4.287013683376792e-4 0.0012245775197423522 5.849726273613556e-4 8454/1017/8945/5684/7321/5707/6500/7316/983/5688/5686/5710/6233/5716/51343/7311/5347/29882/5693/7314 20 Human_rhinovirus_A_serotype_89 R-HSA-162909 Host Interactions of HIV factors 28/1200 129/10654 4.4649844882680085e-4 0.0012724690204440467 6.078500822730242e-4 8945/81929/5684/8065/3159/5707/4869/6500/7316/920/292/3055/5688/5686/2534/5710/5901/6233/5716/7514/1025/9844/7311/3932/5062/5693/7314/5879 28 Human_rhinovirus_A_serotype_89 R-HSA-9020591 Interleukin-12 signaling 14/1200 47/10654 4.6427257314609244e-4 0.0013200745512955716 6.305909312680372e-4 1072/9049/3313/6175/6647/6950/3717/3458/3716/4282/7297/5062/5034/829 14 Human_rhinovirus_A_serotype_89 R-HSA-168254 Influenza Infection 32/1200 155/10654 4.669874985836372e-4 0.001324741547706226 6.328203247594358e-4 3303/81929/5434/6194/6191/6159/6147/6129/6217/8106/6125/821/811/6224/9636/6232/6175/6210/3320/5901/6139/6233/7514/7311/1213/5610/3921/6188/6189/6161/3304/6122 32 Human_rhinovirus_A_serotype_89 R-HSA-5626467 RHO GTPases activate IQGAPs 11/1200 32/10654 4.8332851652892883e-4 0.001364822401365442 6.519666849480914e-4 79861/71/1499/10382/7277/7846/999/347733/10383/801/5879 11 Human_rhinovirus_A_serotype_89 R-HSA-8941326 RUNX2 regulates bone development 11/1200 32/10654 4.8332851652892883e-4 0.001364822401365442 6.519666849480914e-4 25/5594/3280/5925/10013/9759/10413/6714/7525/367/5595 11 Human_rhinovirus_A_serotype_89 R-HSA-186797 Signaling by PDGF 16/1200 58/10654 4.894298415965365e-4 0.001378895946415813 6.586895248595539e-4 5295/4893/5290/5335/5291/6778/6774/6714/5159/6654/2885/1398/9564/3845/3265/5156 16 Human_rhinovirus_A_serotype_89 R-HSA-112409 RAF-independent MAPK1/3 activation 9/1200 23/10654 5.31408890895219e-4 0.0014937552878466975 7.1355707685247e-4 5604/5594/983/3717/3716/1843/7297/3569/5595 9 Human_rhinovirus_A_serotype_89 R-HSA-1059683 Interleukin-6 signaling 6/1200 11/10654 5.641575105904847e-4 0.0015750460816032989 7.523891543955024e-4 6774/867/3717/3716/7297/3569 6 Human_rhinovirus_A_serotype_89 R-HSA-111458 Formation of apoptosome 6/1200 11/10654 5.641575105904847e-4 0.0015750460816032989 7.523891543955024e-4 842/5594/54205/331/317/5595 6 Human_rhinovirus_A_serotype_89 R-HSA-9627069 Regulation of the apoptosome activity 6/1200 11/10654 5.641575105904847e-4 0.0015750460816032989 7.523891543955024e-4 842/5594/54205/331/317/5595 6 Human_rhinovirus_A_serotype_89 R-HSA-195253 Degradation of beta-catenin by the destruction complex 20/1200 82/10654 6.046489248224405e-4 0.0016842816551487392 8.045702694560215e-4 8454/8945/5684/7090/1499/5707/1452/6500/7316/2932/5688/5686/5710/6233/5716/7311/5518/5693/7314/5515 20 Human_rhinovirus_A_serotype_89 R-HSA-202430 Translocation of ZAP-70 to Immunological synapse 8/1200 19/10654 6.10327677157226e-4 0.0016962710666937318 8.102975324989249e-4 3123/3126/3115/3122/920/3932/3127/3125 8 Human_rhinovirus_A_serotype_89 R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 7/1200 15/10654 6.415224001235783e-4 0.0017789632398932487 8.49799039785225e-4 7316/4233/867/6233/2885/7311/7314 7 Human_rhinovirus_A_serotype_89 R-HSA-68949 Orc1 removal from chromatin 18/1200 71/10654 6.82880101583301e-4 0.001889403689134066 9.025557160411814e-4 8454/1017/4172/5684/5707/6500/7316/4174/4171/5688/6502/5686/5710/6233/5716/7311/5693/7314 18 Human_rhinovirus_A_serotype_89 R-HSA-948021 Transport to the Golgi and subsequent modification 36/1200 185/10654 6.935259876456696e-4 0.0019145661493394997 9.145756577924761e-4 10113/11014/79861/11258/55291/1783/10382/93661/55860/830/7277/10671/1780/1781/8655/84516/1639/832/3998/10121/8775/55014/7846/347733/51143/3630/10540/6709/83696/5537/10383/1453/140735/829/51164/1778 36 Human_rhinovirus_A_serotype_89 R-HSA-69473 G2/M DNA damage checkpoint 22/1200 95/10654 7.084490220309841e-4 0.001951397529433559 9.321697658302423e-4 6118/5883/7531/7532/2810/545/7534/983/641/6119/3364/10524/995/1111/7157/672/9025/6117/7334/7465/5810/7529 22 Human_rhinovirus_A_serotype_89 R-HSA-156902 Peptide chain elongation 21/1200 89/10654 7.149688497264054e-4 0.001964970068067671 9.386532782716846e-4 6194/6191/1938/6159/6147/6129/1915/6217/6125/6224/6232/6175/6210/6139/6233/7311/3921/6188/6189/6161/6122 21 Human_rhinovirus_A_serotype_89 R-HSA-8856688 Golgi-to-ER retrograde transport 28/1200 133/10654 7.466171884931977e-4 0.0020473902457791245 9.780248551022003e-4 11014/79861/11258/1783/10382/93661/55860/830/7277/10671/1780/5048/1781/8655/84516/1639/832/10121/8775/7846/347733/51143/10540/10383/140735/829/51164/1778 28 Human_rhinovirus_A_serotype_89 R-HSA-3858494 Beta-catenin independent WNT signaling 30/1200 146/10654 7.515240462952389e-4 0.002056276437091629 9.822697302493493e-4 27161/815/5684/6885/5579/1499/5707/5578/5582/3708/192670/7316/5688/5686/5710/192669/23513/6233/5716/7311/1213/387/5593/3845/26523/801/5693/4920/7314/5879 30 Human_rhinovirus_A_serotype_89 R-HSA-5627123 RHO GTPases activate PAKs 9/1200 24/10654 7.660522372921139e-4 0.0020913904000408596 9.990434394121653e-4 3984/4627/2316/4771/5063/5058/801/5062/5879 9 Human_rhinovirus_A_serotype_89 R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 18/1200 72/10654 8.164745158405845e-4 0.0022241270475657424 0.0010624508629504526 5684/7321/5707/9212/7316/6790/5688/6502/5686/5710/6233/5716/51343/7311/5347/29882/5693/7314 18 Human_rhinovirus_A_serotype_89 R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 15/1200 55/10654 8.293817880142877e-4 0.002249356321779409 0.0010745027213140568 8454/8945/5684/5707/6500/7316/5688/5686/5710/6233/5716/51343/7311/5693/7314 15 Human_rhinovirus_A_serotype_89 R-HSA-8941858 Regulation of RUNX3 expression and activity 15/1200 55/10654 8.293817880142877e-4 0.002249356321779409 0.0010745027213140568 5684/1029/5707/7316/6714/5688/5686/2033/5710/6233/5716/7311/5693/7314/4193 15 Human_rhinovirus_A_serotype_89 R-HSA-69052 Switching of origins to a post-replicative state 21/1200 90/10654 8.35652860726765e-4 0.002261393925738658 0.0010802530055562982 8454/1017/4172/5684/7321/5707/6500/7316/4174/4171/5688/6502/5686/5710/6233/5716/51343/7311/29882/5693/7314 21 Human_rhinovirus_A_serotype_89 R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 12/1200 39/10654 8.469616140438645e-4 0.0022869816886873715 0.0010924761116309206 6118/5888/5883/545/641/6119/3364/10524/1111/672/6117/5810 12 Human_rhinovirus_A_serotype_89 R-HSA-157118 Signaling by NOTCH 43/1200 235/10654 8.51593801960538e-4 0.00229446888999848 0.0010960526984553007 8454/27161/3725/5684/7090/5584/2648/55869/5707/207/3280/23220/6500/3091/10013/192670/7534/7316/1950/9759/4609/10014/22938/5688/1387/5686/2033/408/595/55294/5710/192669/3066/7157/83737/6233/2324/5716/7311/1956/26523/5693/7314 43 Human_rhinovirus_A_serotype_89 R-HSA-927802 Nonsense-Mediated Decay (NMD) 25/1200 115/10654 8.622853918088436e-4 0.0023131742902002457 0.0011049881451097308 6194/6191/6159/6147/6129/6217/6125/6224/6232/2935/6175/6210/6139/6233/23381/7311/5518/3921/6188/6189/23293/23049/6161/6122/5515 25 Human_rhinovirus_A_serotype_89 R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 25/1200 115/10654 8.622853918088436e-4 0.0023131742902002457 0.0011049881451097308 6194/6191/6159/6147/6129/6217/6125/6224/6232/2935/6175/6210/6139/6233/23381/7311/5518/3921/6188/6189/23293/23049/6161/6122/5515 25 Human_rhinovirus_A_serotype_89 R-HSA-8943724 Regulation of PTEN gene transcription 16/1200 61/10654 8.966808734868624e-4 0.002400226025776113 0.0011465721866711794 3725/5468/1822/2146/6045/5594/10014/6009/6615/3066/7157/1107/2475/1386/57521/5595 16 Human_rhinovirus_A_serotype_89 R-HSA-5627117 RHO GTPases Activate ROCKs 8/1200 20/10654 9.175638758105687e-4 0.002450809140152039 0.0011707354077327829 1072/3984/4627/3985/9475/6093/387/5058 8 Human_rhinovirus_A_serotype_89 R-HSA-5685942 HDR through Homologous Recombination (HRR) 17/1200 67/10654 9.433758103477976e-4 0.002514310475095426 0.0012010695777987192 6118/5888/5883/545/7316/641/6119/3364/10524/5429/1111/6233/672/7311/6117/5810/7314 17 Human_rhinovirus_A_serotype_89 R-HSA-112315 Transmission across Chemical Synapses 48/1200 272/10654 0.001000859881422942 0.002661769598439462 0.001271509831208819 818/5170/5563/815/4893/79861/5579/5567/817/5578/10382/5594/51422/5582/7277/53632/10645/6714/5566/84254/5571/27330/7846/347733/3084/6195/4137/816/1103/2066/5613/2771/10550/5577/6196/5562/10383/6197/3845/3265/3312/5564/801/5565/814/5879/5595/4193 48 Human_rhinovirus_A_serotype_89 R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 15/1200 56/10654 0.0010169237427314873 0.0026986750506035597 0.0012891393229872844 3303/5684/5707/3315/7316/5688/5686/5710/6233/5716/7311/3304/3312/5693/7314 15 Human_rhinovirus_A_serotype_89 R-HSA-2029481 FCGR activation 6/1200 12/10654 0.0010210730187406609 0.0027038714702274152 0.0012916216184657107 2268/3055/6714/4067/2534/7525 6 Human_rhinovirus_A_serotype_89 R-HSA-1834941 STING mediated induction of host immune responses 7/1200 16/10654 0.0010302415518279606 0.0027223085116824483 0.0013004288719117726 6737/29110/23220/147945/6778/5591/3661 7 Human_rhinovirus_A_serotype_89 R-HSA-400685 Sema4D in semaphorin signaling 9/1200 25/10654 0.001078582606056035 0.0028439549911819383 0.001358538595122311 3984/4627/3985/2064/4233/9475/6093/387/5879 9 Human_rhinovirus_A_serotype_89 R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 10/1200 30/10654 0.0011426632007461703 0.0029937290652245732 0.0014300846852561297 6118/8450/7316/6119/1642/6233/7311/6117/7314/8451 10 Human_rhinovirus_A_serotype_89 R-HSA-4090294 SUMOylation of intracellular receptors 10/1200 30/10654 0.0011426632007461703 0.0029937290652245732 0.0014300846852561297 5241/5468/5465/4306/9759/8856/2099/2908/367/10062 10 Human_rhinovirus_A_serotype_89 R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 10/1200 30/10654 0.0011426632007461703 0.0029937290652245732 0.0014300846852561297 7319/7321/7316/7317/7322/7347/6233/7311/997/7314 10 Human_rhinovirus_A_serotype_89 R-HSA-9018519 Estrogen-dependent gene expression 30/1200 150/10654 0.0011888418596878963 0.0031081162179128477 0.0014847266757921987 27161/3725/596/5434/7090/5241/8204/2625/192670/5885/6667/2099/4609/10524/1387/3320/2033/8243/9126/595/192669/2066/3326/1025/1386/3169/26523/8202/2288/10728 30 Human_rhinovirus_A_serotype_89 R-HSA-69541 Stabilization of p53 15/1200 57/10654 0.0012390200401150113 0.003232453973577006 0.0015441220039265748 5684/1029/5707/7316/4194/5688/5686/5710/7157/6233/5716/7311/5693/7314/4193 15 Human_rhinovirus_A_serotype_89 R-HSA-168255 Influenza Life Cycle 29/1200 144/10654 0.00127218714583951 0.003311980881784716 0.0015821114849436499 3303/81929/5434/6194/6191/6159/6147/6129/6217/6125/821/811/6224/6232/6175/6210/3320/5901/6139/6233/7514/7311/1213/3921/6188/6189/6161/3304/6122 29 Human_rhinovirus_A_serotype_89 R-HSA-180534 Vpu mediated degradation of CD4 14/1200 52/10654 0.0014041126161215974 0.003640073462802629 0.0017388391530917613 8945/5684/5707/6500/7316/920/5688/5686/5710/6233/5716/7311/5693/7314 14 Human_rhinovirus_A_serotype_89 R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 14/1200 52/10654 0.0014041126161215974 0.003640073462802629 0.0017388391530917613 1019/5684/5707/7316/2932/5688/5686/595/5710/6233/5716/7311/5693/7314 14 Human_rhinovirus_A_serotype_89 R-HSA-202131 Metabolism of nitric oxide: eNOS activation and regulation 7/1200 17/10654 0.0015824434526135027 0.004085220126621469 0.001951482786750851 6697/857/207/3320/4846/8976/801 7 Human_rhinovirus_A_serotype_89 R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 7/1200 17/10654 0.0015824434526135027 0.004085220126621469 0.001951482786750851 2308/857/2309/4303/1027/1026/4087 7 Human_rhinovirus_A_serotype_89 R-HSA-202670 ERKs are inactivated 6/1200 13/10654 0.0017164746974266526 0.004412770367967686 0.0021079513828046606 5594/5598/5518/51231/5595/5515 6 Human_rhinovirus_A_serotype_89 R-HSA-203615 eNOS activation 6/1200 13/10654 0.0017164746974266526 0.004412770367967686 0.0021079513828046606 6697/857/207/3320/4846/801 6 Human_rhinovirus_A_serotype_89 R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 12/1200 42/10654 0.0017407707156610994 0.004456661956692524 0.0021289181060716654 8945/7090/1499/207/7534/7316/208/6233/7514/7311/331/7314 12 Human_rhinovirus_A_serotype_89 R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 12/1200 42/10654 0.0017407707156610994 0.004456661956692524 0.0021289181060716654 6118/5888/5883/545/641/6119/3364/10524/1111/672/6117/5810 12 Human_rhinovirus_A_serotype_89 R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 16/1200 65/10654 0.0018589946476675505 0.0047494811495274476 0.002268795908671305 10450/6118/5434/27339/7515/8450/7316/6119/1642/2033/6233/7311/6117/1022/7314/8451 16 Human_rhinovirus_A_serotype_89 R-HSA-202427 Phosphorylation of CD3 and TCR zeta chains 8/1200 22/10654 0.001896210511597773 0.0048245850954879415 0.002304672569711889 3123/3126/3115/3122/920/3932/3127/3125 8 Human_rhinovirus_A_serotype_89 R-HSA-442982 Ras activation upon Ca2+ influx through NMDA receptor 8/1200 22/10654 0.001896210511597773 0.0048245850954879415 0.002304672569711889 818/815/4893/817/816/3845/3265/801 8 Human_SARS_coronavirus R-HSA-449147 Signaling by Interleukins 302/2473 461/10654 1.7127481033844984e-87 2.3498903978435317e-84 1.0168315055882707e-84 5295/729230/8454/6804/6095/3605/3557/7124/1147/5778/5718/2308/54014/834/1052/10148/3725/7291/5777/8945/1326/596/9655/5601/351/9252/3635/6464/2208/3592/5290/3566/1437/3667/4790/6627/6885/6597/5606/2309/5682/90865/5604/4215/64109/3561/26469/5657/3587/5782/5783/7412/6351/3578/7184/5707/27250/27178/356/3593/3589/6775/207/50616/3911/5292/5451/3684/9021/1849/7422/29110/3553/2625/1230/1439/5594/8878/3595/54472/6624/4582/5717/2919/821/6500/3082/5743/3091/941/23118/25930/4318/10538/6367/3726/4312/3383/5705/58480/11009/6097/6349/6657/1438/6778/53833/3576/4615/3581/7534/3313/332/3662/3597/6776/5528/3688/2357/1436/4313/7316/3565/4985/10213/3934/6175/9978/2920/3560/3976/79155/6352/50615/6774/4314/1435/5970/4792/1441/4205/3055/5443/6850/1026/6348/9261/5780/59307/3718/1440/4793/3627/7133/5714/3606/6772/8651/8809/4609/5775/3146/6647/5566/149233/6364/5519/5898/8503/7132/4988/5598/1901/3552/1432/4208/5701/867/79923/6950/3558/4067/3717/29760/4088/3636/598/2247/836/3320/5602/29949/4843/2335/2534/84867/2162/595/57162/9466/5771/3458/10454/6288/5702/2002/998/7157/6648/942/3654/7189/163702/112744/5609/6654/6233/2885/7525/1398/58985/3716/85480/7409/8660/1385/2353/604/282618/7311/6196/53832/3594/1154/6363/2939/1270/50604/9846/6347/3932/3575/7076/5293/5518/302/1386/6382/5296/7040/3687/6935/3588/51561/3570/8835/5599/5600/5784/7431/6777/6356/3600/5008/3977/3312/3559/3929/3551/246778/55801/6773/7850/7297/6416/5781/5608/3569/3162/1489/5062/1278/4170/3689/1234/3601/3586/4791/5724/3554/51231/4692/829/7314/3572/3596/5595/5515/59067/257397/3556/5516 302 Human_SARS_coronavirus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 102/2473 108/10654 1.666672604658567e-57 1.1433374067957769e-54 4.9473860475127994e-55 5295/6095/3605/7124/2308/1052/7291/596/9655/2208/3592/3566/2309/3561/7412/7184/356/3593/207/3911/5292/5451/3684/9021/7422/3553/2625/6624/4582/3082/5743/3091/4318/10538/6367/3726/4312/3383/58480/6097/6657/6778/3576/332/3662/3597/3688/4313/3565/4985/3934/3976/6774/4314/5443/1026/3718/7133/3606/6772/8651/4609/149233/4988/1901/3552/79923/3717/598/2247/3320/4843/2335/2162/595/6288/7157/112744/3716/2353/604/6347/7076/7040/3687/6935/51561/3570/7431/6356/5008/3312/3929/7297/3569/3162/1278/4170/3689/3586/4692/3596 102 Human_SARS_coronavirus R-HSA-5663202 Diseases of signal transduction 218/2473 377/10654 4.475897802195972e-49 2.0469772615376248e-46 8.857566176977295e-47 5295/8454/1147/5718/2308/818/5170/2963/815/8805/5434/5440/22906/4893/11052/6464/26127/8841/685/5290/3667/22943/5335/71/79718/1487/2309/5682/1499/5604/2648/10018/5525/9734/892/10142/842/139285/3815/572/5707/10956/5430/5526/8844/23462/817/207/51564/5436/1452/7039/5594/3280/4303/84335/613/4041/5717/1027/9372/7249/6500/409/930/3082/7414/941/10013/2064/5705/5441/6199/2260/5438/9208/5431/6776/5528/2100/5435/4686/7316/10213/673/9978/5433/1950/9611/8546/6774/2263/89780/4233/9759/8658/9612/1026/1024/5714/6772/6714/2099/6934/5605/4609/5664/7415/64223/4089/10014/2962/22938/5519/8850/8503/399687/2932/10256/2261/5701/867/1387/5437/5159/7046/3717/4088/2247/2244/6907/3164/10000/3320/26508/324/2335/2534/2033/3690/408/391/55294/5728/8312/5529/1445/5439/816/5702/3066/3065/2280/2066/5894/4087/942/208/9794/6654/6233/5527/2885/1488/79109/2475/2266/7409/56829/8660/4040/1385/7048/7311/8826/9846/3932/2931/5293/5518/5155/2243/7450/1956/6469/7855/60/4254/118788/5296/7040/3845/388585/6777/3265/3516/369/801/4763/5781/4851/5432/22916/5663/7750/11140/5245/7529/5156/940/7314/1523/5879/253260/5595/4193/5515/5516 218 Human_SARS_coronavirus R-HSA-141424 Amplification of signal from the kinetochores 88/2473 96/10654 8.00996607710501e-47 2.1979346915576145e-44 9.510780773657317e-45 220134/5905/55839/11130/4928/79682/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/401541/79019/5526/348235/80152/9212/1063/8379/3619/79172/147841/348995/23421/55920/79023/57122/79980/64105/6232/332/1780/23122/5528/5048/1781/5501/57405/8655/4085/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/22919/1060/91687/79003/5529/51143/83540/11004/5527/701/7514/9184/5518/54820/5347/57551/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/5515/1778/5516 88 Human_SARS_coronavirus R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 88/2473 96/10654 8.00996607710501e-47 2.1979346915576145e-44 9.510780773657317e-45 220134/5905/55839/11130/4928/79682/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/401541/79019/5526/348235/80152/9212/1063/8379/3619/79172/147841/348995/23421/55920/79023/57122/79980/64105/6232/332/1780/23122/5528/5048/1781/5501/57405/8655/4085/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/22919/1060/91687/79003/5529/51143/83540/11004/5527/701/7514/9184/5518/54820/5347/57551/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/5515/1778/5516 88 Human_SARS_coronavirus R-HSA-2500257 Resolution of Sister Chromatid Cohesion 105/2473 126/10654 9.722426206768077e-47 2.2231947926143e-44 9.620084878275782e-45 220134/5905/55839/11130/4928/79682/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/401541/79019/5526/348235/80152/10382/9212/1063/347688/8379/3619/79172/10274/147841/23244/7277/348995/23421/55920/79023/9133/10381/57122/79980/64105/10735/6232/332/23047/1780/23122/5885/5528/5048/1781/891/5501/57405/8655/4085/983/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/22919/1060/91687/79003/8243/9126/10376/5529/51143/83540/11004/5527/701/7514/9184/5518/10383/54820/5347/113130/57551/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/5515/1778/5516 105 Human_SARS_coronavirus R-HSA-69618 Mitotic Spindle Checkpoint 97/2473 112/10654 2.4497964575934957e-46 4.801601056883252e-44 2.0777221083950854e-44 220134/5905/55839/11130/4928/79682/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/7321/991/401541/79019/5526/348235/80152/8697/9212/1063/8379/3619/79172/147841/348995/23421/55920/79023/57122/79980/64105/6232/332/1780/8881/23122/5528/5048/1781/5501/57405/8655/4085/23279/55166/51433/79902/3796/54821/5519/9183/81565/2491/1062/699/22919/1060/91687/79003/5529/51143/83540/29945/10393/11004/5527/51434/701/7514/9184/5518/54820/5347/57551/84643/29882/6396/23332/25909/64946/9793/10726/81930/55746/140735/996/5515/1778/5516 97 Human_SARS_coronavirus R-HSA-9006936 Signaling by TGF-beta family members 91/2473 102/10654 5.804405092963329e-46 9.95455473443211e-44 4.3074795689885766e-44 4093/57154/5590/892/7027/9765/7321/51377/25805/6497/10273/5045/9372/269/50855/4086/658/51592/3726/23370/64750/50848/659/130399/7323/8239/54778/7316/1875/9611/5501/91/93/3624/9612/56937/1024/6667/5933/4092/4609/4089/22938/11171/60436/23327/867/23645/8812/7050/7046/92/4088/650/1874/142/905/94/5494/3065/2280/6498/9958/4087/5499/657/6233/3625/7514/7048/1025/1030/7311/56288/25937/9110/8928/387/7040/57530/10589/904/23439/2658/4091/5500/268/4090/7314/4221/5054 91 Human_SARS_coronavirus R-HSA-68877 Mitotic Prometaphase 139/2473 200/10654 1.274513089354227e-44 1.9429243984377772e-42 8.40731441398578e-43 10844/115106/220134/5905/55839/11130/4928/55559/79682/5903/10403/54908/6249/55143/22981/55055/25936/5525/9735/7531/80776/10142/1459/1783/1058/991/401541/203068/79019/5526/54801/7532/1454/348235/80152/10382/9212/1063/347688/8379/95681/3619/79172/10274/121441/1460/147841/23244/7277/348995/23421/79441/55920/79023/9133/10381/57122/79980/64105/10735/5116/6232/332/23047/1780/10051/23122/5885/5528/5048/1781/23354/891/5501/57405/8655/4085/9738/1457/983/1639/23279/55166/79902/5566/3796/54821/5519/84131/9183/81565/2491/1062/699/7283/3320/22919/1060/91687/79003/8243/9126/10376/10426/5529/51143/83540/4751/11004/5577/5527/701/7514/9184/54930/5518/10383/54820/5347/113130/57551/84643/6396/9662/55142/23332/1453/25909/64946/9793/10726/81930/55746/140735/93323/55755/5515/1778/5516 139 Human_SARS_coronavirus R-HSA-9006925 Intracellular signaling by second messengers 182/2473 305/10654 1.1800900827282144e-43 1.61908359350311e-41 7.006008491144347e-42 5295/1912/1147/5718/2308/818/5170/27161/3725/6591/815/3643/3838/8841/685/5290/3667/5335/2309/5682/90865/5468/5525/1822/5575/23186/1459/842/3815/572/5707/5567/2146/5978/5526/9112/9219/8535/817/10273/207/51564/6045/7039/57690/5594/4303/84335/5568/84232/5717/1027/7249/27327/80012/930/3082/5931/1460/112/941/3708/2064/57761/5705/6199/192670/2260/4615/5573/5528/2100/7316/10213/1950/2263/111/1457/4233/8658/1026/1911/4734/3709/10768/5714/6714/2099/1108/57167/2122/11060/7101/64223/5566/81847/10014/5519/8503/1958/5928/2932/2261/5701/84733/5159/57459/5576/2247/3164/10000/54815/2534/23512/57332/391/5728/5529/6615/816/3630/192669/5702/3066/3065/7157/1107/2066/23028/5613/942/3654/7189/5371/23112/208/10542/5577/6233/5527/2885/79109/5580/2475/7409/8660/1385/57504/7311/3932/2931/5293/5518/5155/1386/3710/1956/4254/118788/5296/5581/331/4343/8726/23466/26523/7874/801/5781/53615/57521/5156/940/7314/5879/6015/253260/5595/4193/5515/3556/5516 182 Human_SARS_coronavirus R-HSA-5663220 RHO GTPases Activate Formins 109/2473 140/10654 5.2800170392505275e-43 6.585621252592477e-41 2.8496934068299496e-41 220134/5905/55839/11130/4928/79682/5903/10403/54908/71/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/1856/401541/79019/5526/348235/80152/10382/9212/389/1063/6722/347688/8379/3619/79172/147841/7277/348995/23421/55920/79023/10381/57122/79980/64105/6232/332/1780/23122/5528/3688/5048/1781/5501/57405/8655/4085/81624/6714/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/51466/22919/1060/91687/79003/10376/5529/51143/998/83540/11004/1855/5527/701/1857/7514/9184/5518/10383/54820/5347/387/57551/60/84643/5217/6396/23332/25909/64946/9793/10726/81930/55746/140735/5879/5515/1778/5516 109 Human_SARS_coronavirus R-HSA-170834 Signaling by TGF-beta Receptor Complex 70/2473 73/10654 5.418979349797893e-41 6.195699723268924e-39 2.680968730952642e-39 57154/5590/892/7027/7321/51377/25805/6497/10273/5045/9372/50855/51592/3726/23370/64750/50848/7323/8239/54778/7316/1875/9611/5501/9612/56937/1024/6667/5933/4092/4609/4089/22938/11171/60436/23327/867/23645/8812/7050/7046/4088/1874/142/905/5494/3065/2280/6498/9958/4087/5499/6233/7514/7048/1025/1030/7311/56288/25937/9110/387/7040/57530/904/23439/5500/7314/4221/5054 70 Human_SARS_coronavirus R-HSA-1257604 PIP3 activates AKT signaling 159/2473 264/10654 6.787521349817486e-39 7.163445609191993e-37 3.099726349228391e-37 5295/1912/1147/5718/2308/5170/27161/3725/6591/3643/8841/685/5290/3667/2309/5682/90865/5468/5525/1822/23186/1459/842/3815/572/5707/2146/5978/5526/9112/9219/8535/10273/207/51564/6045/7039/57690/5594/4303/84335/84232/5717/1027/7249/27327/80012/930/3082/5931/1460/941/2064/57761/5705/6199/192670/2260/4615/5528/2100/7316/10213/1950/2263/1457/4233/8658/1026/1911/4734/5714/6714/2099/1108/57167/2122/11060/7101/64223/81847/10014/5519/8503/1958/5928/2932/2261/5701/84733/5159/57459/2247/3164/10000/54815/2534/23512/57332/391/5728/5529/6615/3630/192669/5702/3066/3065/7157/1107/2066/23028/942/3654/7189/5371/23112/208/10542/6233/5527/2885/79109/2475/7409/8660/1385/57504/7311/3932/2931/5293/5518/5155/1386/1956/4254/118788/5296/331/4343/8726/23466/26523/7874/5781/53615/57521/5156/940/7314/5879/6015/253260/5595/4193/5515/3556/5516 159 Human_SARS_coronavirus R-HSA-68882 Mitotic Anaphase 131/2473 201/10654 2.079314289243371e-37 2.0377280034585038e-35 8.817543301753844e-36 5718/220134/5905/55839/11130/4928/79682/5903/10403/54908/6249/55143/5682/55055/25936/5525/9735/80776/1783/1058/7321/5707/991/401541/79019/5526/348235/80152/8697/10382/9212/1063/347688/8379/5717/3619/79172/10274/147841/23244/7277/348995/23421/55920/79023/10381/57122/5705/79980/64105/10735/6232/332/7443/23047/1780/8881/23122/5885/5528/5048/1781/7316/10213/5501/57405/8655/4085/5714/23279/55166/51433/79902/3796/54821/5519/9183/81565/5701/2491/1062/699/22919/1060/91687/79003/8243/9126/10376/5529/51143/5702/5520/83540/2010/29945/10393/11004/9232/23592/6233/9700/5527/51434/701/7514/7311/9184/5518/10383/54820/5347/113130/57551/84643/29882/6396/23332/25909/64946/9793/10726/81930/55746/7112/140735/7314/996/5515/1778/5516 131 Human_SARS_coronavirus R-HSA-2467813 Separation of Sister Chromatids 126/2473 190/10654 3.434549822147864e-37 3.1414682373245795e-35 1.359358666450102e-35 5718/220134/5905/55839/11130/4928/79682/5903/10403/54908/6249/55143/5682/55055/25936/5525/9735/80776/1783/1058/7321/5707/991/401541/79019/5526/348235/80152/8697/10382/9212/1063/347688/8379/5717/3619/79172/10274/147841/23244/7277/348995/23421/55920/79023/10381/57122/5705/79980/64105/10735/6232/332/23047/1780/8881/23122/5885/5528/5048/1781/7316/10213/5501/57405/8655/4085/5714/23279/55166/51433/79902/3796/54821/5519/9183/81565/5701/2491/1062/699/22919/1060/91687/79003/8243/9126/10376/5529/51143/5702/83540/29945/10393/11004/9232/6233/9700/5527/51434/701/7514/7311/9184/5518/10383/54820/5347/113130/57551/84643/29882/6396/23332/25909/64946/9793/10726/81930/55746/140735/7314/996/5515/1778/5516 126 Human_SARS_coronavirus R-HSA-2555396 Mitotic Metaphase and Anaphase 131/2473 202/10654 4.602266058960694e-37 3.946443145558795e-35 1.7076829324038364e-35 5718/220134/5905/55839/11130/4928/79682/5903/10403/54908/6249/55143/5682/55055/25936/5525/9735/80776/1783/1058/7321/5707/991/401541/79019/5526/348235/80152/8697/10382/9212/1063/347688/8379/5717/3619/79172/10274/147841/23244/7277/348995/23421/55920/79023/10381/57122/5705/79980/64105/10735/6232/332/7443/23047/1780/8881/23122/5885/5528/5048/1781/7316/10213/5501/57405/8655/4085/5714/23279/55166/51433/79902/3796/54821/5519/9183/81565/5701/2491/1062/699/22919/1060/91687/79003/8243/9126/10376/5529/51143/5702/5520/83540/2010/29945/10393/11004/9232/23592/6233/9700/5527/51434/701/7514/7311/9184/5518/10383/54820/5347/113130/57551/84643/29882/6396/23332/25909/64946/9793/10726/81930/55746/7112/140735/7314/996/5515/1778/5516 131 Human_SARS_coronavirus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 232/2473 473/10654 2.973011925449383e-36 2.3993955068920904e-34 1.038253081085729e-34 5295/54106/26999/5170/4908/5777/627/1173/2963/3643/5434/5440/5590/9252/4893/8065/6464/685/857/5290/3667/85440/5335/71/5241/5579/5770/4915/6678/1499/5604/2904/5340/26469/5747/4690/5782/3815/5567/8027/7424/5430/10048/10273/207/5436/3911/1849/7422/2060/7039/5045/5594/5568/2322/1785/3315/3082/3178/9101/23118/51741/4318/3708/2064/57761/5921/5441/58513/1277/1280/6778/2260/160/3912/5438/5431/6696/6776/5528/9306/5435/3688/4686/7316/673/1500/5433/1950/5753/9611/9047/6774/2263/11059/4205/4233/7423/9261/4734/3915/3709/10768/10413/6772/6714/2099/8651/5605/5664/64223/5566/8569/2962/1281/5519/5898/8503/5598/1432/2261/4208/867/5437/5159/4670/4067/3717/4909/2247/4914/529/55824/10000/9146/3320/2335/2534/9475/3690/64759/4846/3728/4803/5771/1445/5439/1111/5603/3630/2002/998/2066/83737/3481/3913/3925/208/6654/30011/6233/2885/7525/1398/79109/7410/5580/2475/7409/8660/6093/1385/3685/163/7073/7311/6196/9846/3932/3479/5518/5155/1213/3791/387/3710/1956/60/4254/8851/5296/29924/5581/581/3845/10076/5600/6777/3265/5058/6300/801/1020/5781/30849/7057/5062/5432/1278/3480/22916/5663/4486/10254/10252/11140/51231/4916/7529/5156/5829/7314/5879/253260/161742/5595/2887/5515/25920/6387/5516/2242 232 Human_SARS_coronavirus R-HSA-5663205 Infectious disease 199/2473 383/10654 1.3821368674257778e-35 1.0534954345045373e-33 4.558626860983268e-34 3839/6804/6158/6884/5718/137492/3303/5905/51652/8945/1173/4928/6144/2963/3837/3838/6203/5434/5440/164/5903/9349/8065/4736/6857/7852/6206/6194/6191/162/6128/5606/5682/6132/1499/5604/1938/3159/6147/6129/25978/6217/51160/3843/5707/2959/8027/5430/27243/6874/6222/5436/6152/6136/2060/5045/1174/6125/5717/4869/821/6500/6749/348995/6141/9636/6202/79023/57122/5705/5441/23636/91782/6232/160/5438/6134/6169/5431/919/79720/5435/4686/7316/10213/1500/6175/9978/293/5433/6218/6872/2960/292/4233/567/3055/4836/926/9397/51271/5714/6193/6714/23279/4927/6210/5605/6231/6229/11224/6205/79902/6130/9150/2962/6142/10898/3840/6204/23327/118429/5701/867/6228/5437/8812/23225/999/9146/3320/2534/905/2068/5439/6124/5702/5902/5901/6207/8086/6873/3836/5609/30011/6233/2885/3326/7514/163/1025/7311/9972/3932/1213/93343/5610/6908/3921/6188/6189/8021/7040/7251/8905/6396/6135/6201/904/6883/55690/1104/51497/2547/801/2961/6187/6416/5608/5062/5432/55746/22916/6208/1234/10254/6157/6137/8907/8480/92421/6122/6133/2957/940/7314/5879/25920/6230 199 Human_SARS_coronavirus R-HSA-195258 RHO GTPase Effectors 174/2473 327/10654 7.313318277516832e-33 5.280985619343734e-31 2.2851587304817137e-31 220134/26999/5905/5170/55839/11130/4928/25/79682/5590/5903/10403/54908/71/6249/51517/55143/5579/1499/55055/25936/5525/9735/7531/5747/80776/4690/1783/1058/4659/10093/991/1856/401541/79019/5526/4627/2316/7532/10971/348235/80152/4771/10382/9212/389/5594/1063/6722/347688/8379/1027/3619/10627/79172/1080/7533/2810/147841/7277/348995/23421/55920/79023/10381/57122/79980/64105/6232/7534/94274/332/1780/6242/23122/5528/3688/5048/1781/5501/57405/10398/8655/4085/10552/81624/10094/6279/6714/23279/55166/79902/3796/54821/5519/9183/1432/81565/4637/2491/1062/699/999/51466/22919/9475/1060/91687/995/3895/79003/10376/391/5529/51143/998/4628/23028/695/83540/11004/8976/1855/5527/2885/5585/10096/5580/701/10097/1857/7514/6093/9184/57120/367/8826/10499/5518/10383/103910/54820/5347/387/57551/60/5300/84643/5217/6396/5600/10095/23332/25909/5058/801/64946/9793/10726/30849/10109/81930/5062/55746/4660/140735/5500/7529/5879/4221/5595/5515/1778/5516 174 Human_SARS_coronavirus R-HSA-68886 M Phase 194/2473 395/10654 1.9280615067061075e-30 1.3226501936003897e-28 5.723298367274973e-29 10844/115106/5718/220134/5905/55839/11130/4928/55559/79682/5903/10403/54908/6249/55143/5579/5682/22981/55055/25936/5525/9735/7531/80776/10142/1459/1783/1058/7321/5707/991/91754/401541/203068/79019/5526/54801/7532/5862/1454/348235/2801/80152/8697/10382/9212/5594/1063/347688/8379/95681/5717/3619/79172/10274/5861/5925/121441/1460/147841/23244/7277/348995/23421/79441/55920/79023/9133/10381/57122/5705/23636/79980/64105/10735/5116/6232/332/7443/23047/1780/8881/10051/23122/5885/5528/5048/1781/23354/7316/255919/10213/891/5501/26003/57405/8655/4085/9738/1457/983/1639/8548/5714/23279/4927/55166/51433/79902/5566/3796/54821/5519/84131/9183/81565/5701/2491/10112/1062/699/23225/7283/3320/22919/1060/91687/79003/8243/9126/10376/10426/5529/9663/51143/5702/5520/8086/83540/2010/64900/29945/10393/23399/4751/11004/9232/23592/5577/6233/9700/23175/5527/51434/701/7514/7311/9184/54930/9972/5518/55844/10383/54820/5347/113130/57551/8021/84643/29882/6396/9662/55142/23332/1453/25909/64689/64946/9793/10726/6418/81930/55746/7112/140735/93323/55755/8480/7314/996/5595/5515/1778/5516 194 Human_SARS_coronavirus R-HSA-69620 Cell Cycle Checkpoints 153/2473 293/10654 8.442632704387117e-28 5.515853366866249e-26 2.386789396127486e-26 5718/1017/220134/6118/5905/55839/11130/4928/79682/5903/10403/54908/6249/55143/5682/55055/25936/5525/5883/9735/7531/51512/1029/80776/1783/1058/7321/5707/991/401541/79019/5526/7532/8317/10971/348235/80152/8697/9212/1063/51588/8379/5717/1027/3619/63967/79172/7533/2810/147841/348995/23421/4173/55920/79023/9133/472/57122/5705/79980/64105/6232/7534/332/1780/8881/23122/5528/5048/1781/7316/10213/891/993/5501/890/57405/8655/4085/983/1026/84515/641/5714/4171/23279/55166/51433/79902/4194/3796/54821/9656/5519/6119/9183/81565/7341/5701/10524/2491/1062/699/10926/22919/1060/91687/995/79003/5529/51143/1111/5702/7157/8900/83540/29945/10393/8924/11004/6233/5527/51434/701/672/7514/7311/9184/5518/54820/5347/57551/84643/6117/29882/6396/23332/7465/25909/64946/9793/10726/81930/55746/140735/4176/7529/7314/996/4193/5515/1778/5516 153 Human_SARS_coronavirus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 110/2473 182/10654 2.3074170388609343e-27 1.438989171507819e-25 6.22671392305056e-26 1912/6095/7020/7150/5905/4928/6670/5903/1487/55143/5241/83746/3622/5468/7021/1029/8204/9112/8535/51564/1786/6045/9212/51588/3619/4869/3090/80012/7153/10274/348995/51602/79023/6613/57122/23636/10735/2516/332/3183/5465/5885/4306/28996/1655/5970/4792/3190/6996/9759/9612/1911/9994/6790/641/23137/5111/2099/23279/4927/79902/9656/7341/1387/84733/10401/10521/1616/23225/2908/2033/23512/8243/9126/57332/142/3066/3065/23314/7157/1107/6256/8086/668/7329/5371/8924/672/115426/10155/367/9972/10499/9063/25942/8021/6117/6396/11315/55746/8648/7421/6304/4286/4791/8480/10062/6015/4193/8554 110 Human_SARS_coronavirus R-HSA-6783783 Interleukin-10 signaling 45/2473 47/10654 1.3683489416373954e-26 7.825662853388635e-25 3.3862773126524404e-25 729230/3557/7124/2208/3592/1437/3587/6351/3593/3553/1230/2919/5743/941/6367/3383/6349/3576/2357/2920/3976/6352/6774/1435/6348/1440/3627/7133/3606/6364/7132/3552/942/3716/6363/6347/7076/3588/7850/7297/3569/1234/3586/5724/3554 45 Human_SARS_coronavirus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 43/2473 44/10654 1.368920615753114e-26 7.825662853388635e-25 3.3862773126524404e-25 892/7027/7321/6497/51592/3726/64750/7323/8239/54778/7316/1875/9611/9612/1024/6667/5933/4092/4609/4089/22938/60436/23327/8812/7050/4088/1874/142/905/5494/3065/6498/4087/6233/1025/1030/7311/25937/904/23439/7314/4221/5054 43 Human_SARS_coronavirus R-HSA-168254 Influenza Infection 97/2473 155/10654 6.330353204958034e-26 3.474097838880969e-24 1.503292297935297e-24 3839/6158/3303/4928/6144/2963/3837/3838/6203/5434/5440/5903/9349/4736/6206/6194/6191/6128/6132/6147/6129/6217/3843/5430/6222/5436/6152/6136/6125/821/348995/6141/9636/6202/79023/57122/5441/23636/6232/5438/6134/6169/5431/5435/6175/293/5433/6218/6193/23279/4927/6210/6231/6229/11224/6205/79902/6130/2962/6142/10898/3840/6204/6228/5437/23225/3320/5439/6124/5901/6207/8086/3836/6233/7514/7311/9972/1213/5610/3921/6188/6189/8021/7040/6396/6135/6201/6187/5432/55746/6208/6157/6137/8480/6122/6133/6230 97 Human_SARS_coronavirus R-HSA-194315 Signaling by Rho GTPases 205/2473 455/10654 7.552073024025439e-26 3.985170841908808e-24 1.7244409658098577e-24 220134/26999/5905/5170/55839/11130/4928/25/79682/5590/64333/5903/10403/54908/71/6249/51517/55143/5579/1499/55055/25936/5525/392/9735/7531/5747/80776/4690/1783/1058/4659/10093/991/1856/401541/79019/57580/5526/64411/4627/2316/7532/10928/10971/348235/80152/3633/4771/10382/9212/389/5594/1063/6722/347688/613/29127/8379/1027/3619/10627/1894/79172/1080/7533/2810/147841/7277/348995/23421/55920/79023/54509/10381/57122/79980/64105/58480/23370/6232/7534/94274/332/1780/6242/23122/5528/3688/5048/1781/5501/57405/10398/8655/50650/4085/10552/81624/10094/6279/6714/23279/55166/79902/3796/54821/5519/9183/1432/81565/4637/2491/9138/1062/699/94134/999/51466/22919/85360/9475/1060/91687/995/3895/79003/10376/391/57584/5529/9322/58504/397/51143/998/4628/23028/695/83540/51291/2/11004/6654/8976/1855/5527/2885/5585/7410/10096/5580/701/10097/7409/1857/7514/6093/9184/57120/367/8826/10499/5518/10383/103910/54820/5347/387/57551/60/5296/5300/84643/5217/6396/5600/10095/91614/23332/25909/5058/801/64946/9793/10726/30849/10109/81930/5062/55746/9411/4660/140735/2664/5500/7529/5879/10395/4952/4221/5595/5515/1778/5516 205 Human_SARS_coronavirus R-HSA-2990846 SUMOylation 110/2473 188/10654 1.1169140565897125e-25 5.6755780949669835e-24 2.4559045922674384e-24 1912/6095/7020/7150/5905/4928/6670/5903/1487/55143/5241/83746/3622/5468/7021/1029/8204/9112/8535/51564/1786/6045/9212/51588/3619/4869/3090/80012/7153/10274/348995/51602/79023/6613/57122/23636/10735/2516/332/3183/5465/5885/4306/28996/1655/5970/4792/3190/6996/9759/9612/1911/9994/6790/641/23137/5111/2099/23279/4927/79902/9656/7341/1387/84733/10401/10521/1616/23225/2908/2033/23512/8243/9126/57332/142/3066/3065/23314/7157/1107/6256/8086/668/7329/5371/8924/672/115426/10155/367/9972/10499/9063/25942/8021/6117/6396/11315/55746/8648/7421/6304/4286/4791/8480/10062/6015/4193/8554 110 Human_SARS_coronavirus R-HSA-3700989 Transcriptional Regulation by TP53 172/2473 365/10654 1.8597957415738884e-24 9.112999133712053e-23 3.943326309201779e-23 23368/6884/1017/834/6118/5170/27161/27113/3725/2963/5434/5440/4436/3622/5883/7531/1029/7027/1459/79370/5430/9219/6874/7532/207/10971/5436/9212/57690/835/7832/4849/1027/4869/7249/27327/5931/355/7295/4850/7533/2810/1460/6749/472/5441/192670/7534/332/5438/5431/5934/639/5435/7316/5433/891/6872/28996/890/2539/1457/54971/10769/983/1026/54205/5366/6790/641/5933/5111/1108/8797/5395/64223/4194/9150/2962/9656/5519/6119/1647/5928/1432/5571/10524/10848/1387/4848/5437/8812/57459/23019/1616/28984/10000/6794/54815/2033/995/1874/10128/5728/905/2068/5439/1111/192669/3066/3065/7157/1107/8900/8626/6873/5371/23112/208/10498/10542/6233/5527/79109/2475/672/55571/1025/2353/604/7311/7161/5562/5518/1386/6908/4513/5325/8851/5300/581/4343/6117/5600/7159/904/6883/3276/85456/29883/26523/51497/7874/637/317/1020/5608/53615/10397/8795/5432/665/57521/26155/7529/7314/253260/4193/5515/25920/1263/5516 172 Human_SARS_coronavirus R-HSA-76002 Platelet activation, signaling and aggregation 135/2473 262/10654 6.4478155803776756e-24 3.0504837849235074e-22 1.3199883801571722e-22 5295/5170/2149/5777/5590/351/6464/5321/5290/5005/7018/5579/2153/5770/6678/7042/5340/5747/59345/51097/1606/64805/7424/2770/5336/2316/207/7422/5594/5552/5004/409/3082/7414/10490/2157/7277/3708/83706/334/1277/7044/7534/5196/3827/1950/335/2621/308/7423/6850/78991/3709/5768/6714/710/3671/6647/1191/8503/3273/4352/1432/27040/226/197/4067/374354/2244/7114/81/5265/3309/2335/1/2534/3690/408/2162/55664/391/2783/1445/2782/87/8525/5345/998/5894/3481/54676/2/22915/6654/2885/1398/5473/7410/5580/88/2266/7409/1675/3932/7076/3479/5155/2243/7450/387/3710/5296/5581/51368/29789/7040/10916/54863/213/5660/801/5781/7057/1278/7043/2207/2147/5627/2773/6814/5879/5595/5054/139322/7066 135 Human_SARS_coronavirus R-HSA-168898 Toll-like Receptor Cascades 94/2473 155/10654 1.0521236112174508e-23 4.811711981967808e-22 2.082097251672429e-22 54106/8454/1147/3665/3725/8945/1326/5601/351/9252/4790/6885/5606/5604/7184/7321/8737/5336/3684/1849/29110/5594/1785/4214/6500/330/23118/841/7099/4615/338/5528/7323/7316/79155/5970/4792/4205/9261/59307/4793/6279/8651/5775/3146/5519/5598/1432/4208/329/2244/5602/114609/57162/10454/6288/2002/3661/695/3654/7189/5609/6233/10010/2266/1385/81622/2353/7311/6196/5518/2243/1386/8772/5599/5600/7097/3929/3551/6416/5781/30849/5608/3689/4791/51231/1508/7314/5595/5515/148022/257397/1514/5516 94 Human_SARS_coronavirus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 83/2473 129/10654 1.555101586702417e-23 6.882578635341021e-22 2.9781911541601474e-22 8454/1147/3665/3725/8945/1326/5601/351/9252/4790/6885/5606/5604/7321/8737/5336/3684/1849/29110/5594/1785/4214/6500/330/23118/841/7099/4615/5528/7323/7316/79155/5970/4792/4205/9261/59307/4793/8651/5775/3146/5519/5598/1432/4208/329/5602/114609/57162/10454/6288/2002/3661/695/3654/7189/5609/6233/10010/1385/2353/7311/6196/5518/1386/8772/5599/5600/7097/3929/3551/6416/5781/5608/3689/4791/51231/7314/5595/5515/148022/257397/5516 83 Human_SARS_coronavirus R-HSA-168255 Influenza Life Cycle 89/2473 144/10654 2.478228610315795e-23 1.0625405166728971e-21 4.597766237559568e-22 6158/3303/4928/6144/2963/3837/6203/5434/5440/5903/9349/4736/6206/6194/6191/6128/6132/6147/6129/6217/3843/5430/6222/5436/6152/6136/6125/821/348995/6141/6202/79023/57122/5441/23636/6232/5438/6134/6169/5431/5435/6175/5433/6218/6193/23279/4927/6210/6231/6229/11224/6205/79902/6130/2962/6142/6204/6228/5437/23225/3320/5439/6124/5901/6207/8086/3836/6233/7514/7311/9972/1213/3921/6188/6189/8021/6396/6135/6201/6187/5432/55746/6208/6157/6137/8480/6122/6133/6230 89 Human_SARS_coronavirus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 67/2473 94/10654 4.6238117975906176e-23 1.922384783725554e-21 8.318436535378336e-22 8454/1147/3665/3725/8945/1326/5601/351/9252/4790/6885/5606/5604/7321/8737/1849/29110/5594/6500/330/23118/841/5528/7323/7316/79155/5970/4792/4205/9261/4793/3146/5519/5598/1432/4208/329/5602/10454/6288/2002/3661/3654/7189/5609/6233/10010/1385/2353/7311/6196/5518/1386/8772/5599/5600/3551/6416/5608/4791/51231/7314/5595/5515/148022/257397/5516 67 Human_SARS_coronavirus R-HSA-166166 MyD88-independent TLR4 cascade 69/2473 99/10654 8.38647484496609e-23 3.2874981392267077e-21 1.4225479135521431e-21 8454/1147/3665/3725/8945/1326/5601/351/9252/4790/6885/5606/5604/7321/8737/1849/29110/5594/6500/330/23118/841/7099/5528/7323/7316/79155/5970/4792/4205/9261/4793/3146/5519/5598/1432/4208/329/5602/10454/6288/2002/3661/3654/7189/5609/6233/10010/1385/2353/7311/6196/5518/1386/8772/5599/5600/3551/6416/5781/5608/4791/51231/7314/5595/5515/148022/257397/5516 69 Human_SARS_coronavirus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 69/2473 99/10654 8.38647484496609e-23 3.2874981392267077e-21 1.4225479135521431e-21 8454/1147/3665/3725/8945/1326/5601/351/9252/4790/6885/5606/5604/7321/8737/1849/29110/5594/6500/330/23118/841/7099/5528/7323/7316/79155/5970/4792/4205/9261/4793/3146/5519/5598/1432/4208/329/5602/10454/6288/2002/3661/3654/7189/5609/6233/10010/1385/2353/7311/6196/5518/1386/8772/5599/5600/3551/6416/5781/5608/4791/51231/7314/5595/5515/148022/257397/5516 69 Human_SARS_coronavirus R-HSA-5683057 MAPK family signaling cascades 144/2473 294/10654 1.21631344198711e-22 4.6355056733508754e-21 2.0058502376629536e-21 5718/2308/818/27161/2118/3725/815/4893/6464/6711/685/1437/3667/71/2309/5682/5604/2904/3561/5525/5747/153090/10642/3815/5707/5567/5526/8844/10048/817/1849/7010/7039/1439/57690/5594/5568/2322/5717/3315/27327/409/3082/7414/2064/5921/5705/1438/192670/2260/5596/8452/5528/4684/2902/7316/10213/673/9978/1950/3560/2263/4233/983/5597/3718/5714/6714/5605/4609/5566/5519/10256/2261/5701/27040/5159/3558/3717/2247/2244/2335/2534/3690/408/5529/1445/816/192669/5702/998/2066/5894/896/1847/5979/9693/23112/6654/6233/5527/2885/6709/3716/88/2266/8660/7514/7311/8826/5518/5155/2243/7450/1956/60/4254/5536/1843/4343/3570/3845/3265/3559/26523/369/5058/801/4763/7297/5781/8202/3569/5062/5245/7529/5156/7314/3572/5879/161742/5595/5515/5516 144 Human_SARS_coronavirus R-HSA-8939211 ESR-mediated signaling 118/2473 223/10654 2.6557186202301692e-22 9.847691748529168e-21 4.261238411976716e-21 5295/3727/5170/27161/3725/2354/2963/3838/596/5434/5440/5590/4893/6464/685/857/5290/5241/4316/2309/4435/9687/5747/59345/8204/5430/2770/207/5436/5451/7039/2625/57690/5594/6722/1027/3315/27327/10274/51523/4318/5441/10735/192670/5438/5431/5885/2100/5435/4313/5433/1950/1509/865/5469/1655/4314/6667/7033/6714/2099/4609/2962/8850/8503/10524/1387/5437/10000/3320/2033/8243/4846/9126/595/2783/8312/2782/5439/192669/3065/2002/2066/861/23028/23112/208/10498/3326/7514/1385/1025/2353/10499/1386/6908/1956/5536/3169/5296/4343/3845/858/904/3276/3265/26523/23189/801/8202/5432/8648/3480/2773/2957/5595/7528/6387 118 Human_SARS_coronavirus R-HSA-2262752 Cellular responses to stress 204/2473 479/10654 5.146967138472258e-22 1.8583260299957733e-20 8.041245058444192e-21 1912/5718/1017/818/3303/7014/6118/3725/4928/6782/815/1019/5903/5601/2077/573/4790/5241/5606/5682/9448/3159/112399/7531/7290/1029/7027/1915/1783/7321/5707/2146/8535/84962/817/6045/7422/8697/10382/57690/5594/3308/347688/84335/6649/5717/1027/27327/80012/10049/5931/7295/10294/5925/3091/830/7013/7277/348995/1051/1410/10013/79023/472/10381/57122/5705/23636/192670/3576/3313/10808/1780/3490/8881/29855/7323/4306/1781/7316/10213/9978/2114/890/3305/8655/6774/5970/1026/1639/9261/1911/9532/54205/832/6667/5714/23279/4927/7415/6647/8994/51433/79902/64223/4194/2882/6119/26353/5598/3552/5928/10370/1432/2932/5701/10524/1387/84733/57805/23225/529/2908/3309/3320/5602/65057/2033/23512/7266/57332/10376/6767/25842/51143/3301/816/192669/5702/9531/7157/8453/8900/50507/6648/8086/23135/29945/10393/22824/8091/23112/5609/10542/6233/2056/51434/3326/2475/2353/1030/7311/6196/367/9972/3397/2034/10383/23411/8021/4343/8726/55662/6117/29882/5599/6396/5600/3312/23466/4217/26523/3456/2113/405/6416/5608/54386/3569/57521/55746/55466/140735/8480/768/829/7314/996/6015/5595/4193/2950/1778/23043 204 Human_SARS_coronavirus R-HSA-168273 Influenza Viral RNA Transcription and Replication 82/2473 134/10654 3.4016790813737474e-21 1.196693256319175e-19 5.178264512536556e-20 6158/4928/6144/2963/6203/5434/5440/5903/9349/4736/6206/6194/6191/6128/6132/6147/6129/6217/3843/5430/6222/5436/6152/6136/6125/348995/6141/6202/79023/57122/5441/23636/6232/5438/6134/6169/5431/5435/6175/5433/6218/6193/23279/4927/6210/6231/6229/11224/6205/79902/6130/2962/6142/6204/6228/5437/23225/3320/5439/6124/6207/8086/6233/7311/9972/3921/6188/6189/8021/6396/6135/6201/6187/5432/55746/6208/6157/6137/8480/6122/6133/6230 82 Human_SARS_coronavirus R-HSA-6807070 PTEN Regulation 84/2473 140/10654 6.967322966501439e-21 2.3897917775099933e-19 1.0340974087123188e-19 1912/5718/27161/3725/6591/8841/5682/5468/1822/23186/1459/5707/2146/5978/9112/9219/8535/10273/207/51564/6045/57690/5594/84232/5717/27327/80012/5931/1460/5705/192670/7316/10213/1457/8658/1911/4734/5714/1108/57167/2122/11060/7101/64223/81847/10014/1958/5928/5701/84733/57459/10000/54815/23512/57332/5728/6615/192669/5702/3066/3065/7157/1107/23028/5371/23112/208/10542/6233/2475/57504/7311/1386/331/4343/8726/23466/26523/7874/53615/57521/7314/6015/5595 84 Human_SARS_coronavirus R-HSA-400253 Circadian Clock 53/2473 70/10654 1.655818065079824e-20 5.540932647047606e-19 2.3976415627856764e-19 8454/6095/5187/8945/8841/1374/79718/5936/10135/8204/28999/1454/1407/6500/3091/200186/1408/5465/406/4209/7316/9611/5469/5501/8553/64784/4208/1387/150094/2908/6604/6907/1390/2033/6256/5499/10498/6233/1385/7311/10499/23054/8864/1386/9575/23411/1453/23373/8648/5500/96764/7314/5054 53 Human_SARS_coronavirus R-HSA-8953897 Cellular responses to external stimuli 204/2473 493/10654 3.1333495562643176e-20 1.0235608550463436e-18 4.429095613366104e-19 1912/5718/1017/818/3303/7014/6118/3725/4928/6782/815/1019/5903/5601/2077/573/4790/5241/5606/5682/9448/3159/112399/7531/7290/1029/7027/1915/1783/7321/5707/2146/8535/84962/817/6045/7422/8697/10382/57690/5594/3308/347688/84335/6649/5717/1027/27327/80012/10049/5931/7295/10294/5925/3091/830/7013/7277/348995/1051/1410/10013/79023/472/10381/57122/5705/23636/192670/3576/3313/10808/1780/3490/8881/29855/7323/4306/1781/7316/10213/9978/2114/890/3305/8655/6774/5970/1026/1639/9261/1911/9532/54205/832/6667/5714/23279/4927/7415/6647/8994/51433/79902/64223/4194/2882/6119/26353/5598/3552/5928/10370/1432/2932/5701/10524/1387/84733/57805/23225/529/2908/3309/3320/5602/65057/2033/23512/7266/57332/10376/6767/25842/51143/3301/816/192669/5702/9531/7157/8453/8900/50507/6648/8086/23135/29945/10393/22824/8091/23112/5609/10542/6233/2056/51434/3326/2475/2353/1030/7311/6196/367/9972/3397/2034/10383/23411/8021/4343/8726/55662/6117/29882/5599/6396/5600/3312/23466/4217/26523/3456/2113/405/6416/5608/54386/3569/57521/55746/55466/140735/8480/768/829/7314/996/6015/5595/4193/2950/1778/23043 204 Human_SARS_coronavirus R-HSA-109606 Intrinsic Pathway for Apoptosis 44/2473 53/10654 4.160422554789455e-20 1.3274650570165424e-18 5.744132976502455e-19 23368/27113/596/10018/7531/1029/7027/842/572/7532/207/10971/5594/7533/2810/841/7534/8655/6774/54205/4836/5366/598/56616/836/10000/5534/7157/90427/8626/208/7161/840/331/581/5599/7159/57099/637/317/140735/7529/578/5595 44 Human_SARS_coronavirus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 64/2473 95/10654 5.1459214441875475e-20 1.5689342714278477e-18 6.789005133384274e-19 8454/1147/3725/8945/1326/5601/351/9252/4790/6885/5606/5604/1849/5594/4214/6500/23118/7099/4615/5528/7316/79155/5970/4792/4205/9261/59307/4793/8651/3146/5519/5598/1432/4208/5602/114609/57162/10454/6288/2002/695/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/7097/3551/6416/5608/4791/51231/7314/5595/5515/257397/5516 64 Human_SARS_coronavirus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 64/2473 95/10654 5.1459214441875475e-20 1.5689342714278477e-18 6.789005133384274e-19 8454/1147/3725/8945/1326/5601/351/9252/4790/6885/5606/5604/1849/5594/4214/6500/23118/7099/4615/5528/7316/79155/5970/4792/4205/9261/59307/4793/8651/3146/5519/5598/1432/4208/5602/114609/57162/10454/6288/2002/695/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/7097/3551/6416/5608/4791/51231/7314/5595/5515/257397/5516 64 Human_SARS_coronavirus R-HSA-8943724 Regulation of PTEN gene transcription 48/2473 61/10654 6.12113859319674e-20 1.825696119536071e-18 7.900050724400369e-19 1912/3725/6591/8841/5468/1822/23186/2146/5978/9112/9219/8535/51564/6045/5594/84232/80012/5931/1911/1108/57167/2122/7101/64223/10014/1958/5928/84733/57459/54815/23512/57332/6615/3066/3065/7157/1107/23028/10542/2475/57504/1386/8726/23466/53615/57521/6015/5595 48 Human_SARS_coronavirus R-HSA-109581 Apoptosis 96/2473 178/10654 4.0192942520710683e-19 1.173291854008831e-17 5.077003265773981e-18 23368/5718/27113/3837/596/7186/22985/2339/5682/1499/4976/10018/7531/5747/1029/7027/842/572/5707/8737/356/7532/207/10971/5594/10059/5717/63967/355/7533/2810/118/5705/841/7099/7534/100506658/7316/10213/8655/7082/6774/54205/5339/4836/5366/5714/660/8797/3146/8428/5701/10134/329/999/598/56616/836/10000/324/8837/5534/4137/9414/5702/7157/90427/8626/3836/208/6233/5580/6709/6093/7311/7161/840/8772/331/581/5599/8717/7159/7431/57099/637/317/8795/5062/6304/140735/7529/7314/578/5595/148022 96 Human_SARS_coronavirus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 62/2473 93/10654 4.483006446236597e-19 1.2552418049462472e-17 5.431612536363998e-18 54106/8454/1147/3665/3725/8945/1326/5601/351/9252/4790/6885/5606/5604/1849/5594/4214/6500/23118/7099/4615/5528/7316/79155/5970/4792/4205/9261/4793/3146/5519/5598/1432/4208/5602/57162/10454/6288/2002/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/3551/6416/5608/4791/51231/7314/5595/5515/148022/257397/5516 62 Human_SARS_coronavirus R-HSA-975155 MyD88 dependent cascade initiated on endosome 62/2473 93/10654 4.483006446236597e-19 1.2552418049462472e-17 5.431612536363998e-18 54106/8454/1147/3665/3725/8945/1326/5601/351/9252/4790/6885/5606/5604/1849/5594/4214/6500/23118/7099/4615/5528/7316/79155/5970/4792/4205/9261/4793/3146/5519/5598/1432/4208/5602/57162/10454/6288/2002/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/3551/6416/5608/4791/51231/7314/5595/5515/148022/257397/5516 62 Human_SARS_coronavirus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 31/2473 32/10654 4.674878199727012e-19 1.270401588296034e-17 5.497211107863766e-18 892/7027/3726/54778/7316/1875/1024/6667/5933/4092/4609/4089/22938/60436/8812/7050/4088/1874/905/3065/4087/6233/1025/1030/7311/25937/904/23439/7314/4221/5054 31 Human_SARS_coronavirus R-HSA-5357801 Programmed Cell Death 97/2473 181/10654 4.722338265531905e-19 1.270401588296034e-17 5.497211107863766e-18 23368/5718/27113/3837/596/7186/22985/2339/5682/1499/4976/10018/7531/5747/1029/7027/842/572/5707/8737/356/7532/207/10971/5594/10059/5717/63967/355/330/7533/2810/118/5705/841/7099/7534/100506658/7316/10213/8655/7082/6774/54205/5339/4836/5366/5714/660/8797/3146/8428/5701/10134/329/999/598/56616/836/10000/324/8837/5534/4137/9414/5702/7157/90427/8626/3836/208/6233/5580/6709/6093/7311/7161/840/8772/331/581/5599/8717/7159/7431/57099/637/317/8795/5062/6304/140735/7529/7314/578/5595/148022 97 Human_SARS_coronavirus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 64/2473 98/10654 6.110082880852162e-19 1.5817044740621067e-17 6.84426364409259e-18 8454/1147/3725/8945/1326/5601/351/9252/4790/6885/5606/5604/1849/5594/4214/6500/23118/7099/4615/5528/7316/79155/5970/4792/4205/9261/59307/4793/8651/3146/5519/5598/1432/4208/5602/114609/57162/10454/6288/2002/695/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/7097/3551/6416/5608/4791/51231/7314/5595/5515/257397/5516 64 Human_SARS_coronavirus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 64/2473 98/10654 6.110082880852162e-19 1.5817044740621067e-17 6.84426364409259e-18 8454/1147/3725/8945/1326/5601/351/9252/4790/6885/5606/5604/1849/5594/4214/6500/23118/7099/4615/5528/7316/79155/5970/4792/4205/9261/59307/4793/8651/3146/5519/5598/1432/4208/5602/114609/57162/10454/6288/2002/695/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/7097/3551/6416/5608/4791/51231/7314/5595/5515/257397/5516 64 Human_SARS_coronavirus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 58/2473 85/10654 1.1303677632841137e-18 2.7694010200460784e-17 1.1983598091959401e-17 8454/1147/3725/8945/1326/5601/351/9252/4790/6885/5606/5604/1849/5594/4214/6500/23118/4615/5528/7316/79155/5970/4792/4205/9261/4793/3146/5519/5598/1432/4208/5602/57162/10454/6288/2002/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/3551/6416/5608/4791/51231/7314/5595/5515/257397/5516 58 Human_SARS_coronavirus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 58/2473 85/10654 1.1303677632841137e-18 2.7694010200460784e-17 1.1983598091959401e-17 8454/1147/3725/8945/1326/5601/351/9252/4790/6885/5606/5604/1849/5594/4214/6500/23118/4615/5528/7316/79155/5970/4792/4205/9261/4793/3146/5519/5598/1432/4208/5602/57162/10454/6288/2002/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/3551/6416/5608/4791/51231/7314/5595/5515/257397/5516 58 Human_SARS_coronavirus R-HSA-975871 MyD88 cascade initiated on plasma membrane 58/2473 85/10654 1.1303677632841137e-18 2.7694010200460784e-17 1.1983598091959401e-17 8454/1147/3725/8945/1326/5601/351/9252/4790/6885/5606/5604/1849/5594/4214/6500/23118/4615/5528/7316/79155/5970/4792/4205/9261/4793/3146/5519/5598/1432/4208/5602/57162/10454/6288/2002/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/3551/6416/5608/4791/51231/7314/5595/5515/257397/5516 58 Human_SARS_coronavirus R-HSA-162906 HIV Infection 115/2473 233/10654 1.245100570290525e-18 2.9969789165589475e-17 1.2968360510505191e-17 6884/5718/137492/5905/51652/8945/1173/4928/2963/3837/5434/5440/164/5903/8065/7852/162/5682/3159/25978/51160/5707/2959/5430/27243/6874/5436/5045/1174/5717/4869/6500/6749/348995/79023/57122/5705/5441/23636/91782/160/5438/5431/919/79720/5435/4686/7316/10213/9978/293/5433/6872/2960/292/567/3055/4836/926/9397/51271/5714/23279/4927/79902/9150/2962/23327/5701/5437/8812/23225/2534/905/2068/5439/5702/5902/5901/8086/6873/3836/6233/7514/163/1025/7311/9972/3932/93343/6908/8021/7251/8905/6396/904/6883/55690/1104/51497/2547/2961/5062/5432/55746/22916/1234/8907/8480/92421/2957/940/7314/5879/25920 115 Human_SARS_coronavirus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 61/2473 92/10654 1.312342882280088e-18 3.104369714634967e-17 1.3433056000108342e-17 54106/8454/1147/3725/8945/1326/5601/351/9252/4790/6885/5606/5604/1849/5594/4214/6500/23118/7099/4615/5528/7316/79155/5970/4792/4205/9261/4793/3146/5519/5598/1432/4208/5602/57162/10454/6288/2002/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/3551/6416/5608/4791/51231/7314/5595/5515/148022/257397/5516 61 Human_SARS_coronavirus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 40/2473 48/10654 1.660148530698772e-18 3.86054878664189e-17 1.670515203058176e-17 5295/5777/3635/6464/5290/1437/3561/1439/1438/7534/6776/7316/3560/3055/6850/3718/5566/8503/867/3558/4067/3717/29760/3636/2534/6654/6233/2885/7525/1398/3716/7409/7311/9846/5293/5296/6777/3559/5781/7314 40 Human_SARS_coronavirus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 63/2473 97/10654 1.7529683405561227e-18 4.008454272071667e-17 1.7345160422344795e-17 54106/8454/1147/3665/3725/8945/1326/5601/351/9252/4790/6885/5606/5604/1849/5594/4214/6500/23118/7099/4615/5528/7316/79155/5970/4792/4205/9261/4793/3146/5519/5598/1432/4208/5602/57162/10454/6288/2002/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/3551/6416/30849/5608/4791/51231/7314/5595/5515/148022/257397/5516 63 Human_SARS_coronavirus R-HSA-450294 MAP kinase activation 48/2473 64/10654 2.129255369968475e-18 4.789079291142209e-17 2.0723037595551682e-17 8454/1147/3725/8945/1326/5601/9252/4790/6885/5606/5604/1849/5594/6500/23118/5528/7316/79155/4205/9261/5519/5598/1432/4208/5602/10454/2002/3654/7189/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/3551/6416/5608/51231/7314/5595/5515/257397/5516 48 Human_SARS_coronavirus R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 78/2473 134/10654 2.2197178557205466e-18 4.912020803304177e-17 2.1255023270397088e-17 351/5005/7018/5579/2153/6678/7042/5340/51097/7424/2316/7422/5552/5004/3082/7414/10490/2157/7277/83706/334/7044/5196/3827/1950/335/2621/308/7423/78991/5768/710/3671/6647/1191/3273/226/197/374354/2244/7114/81/5265/3309/2335/1/3690/2162/55664/87/5345/3481/54676/2/22915/5473/88/2266/1675/7076/3479/5155/2243/7450/51368/29789/7040/10916/54863/213/5660/801/7057/7043/5627/6814/5054/139322 78 Human_SARS_coronavirus R-HSA-114608 Platelet degranulation 76/2473 129/10654 2.2993306868474627e-18 5.0074312735789187e-17 2.1667878151745515e-17 351/5005/7018/2153/6678/7042/5340/51097/7424/2316/7422/5552/5004/3082/7414/10490/2157/7277/83706/334/7044/5196/3827/1950/335/2621/308/7423/78991/5768/710/3671/6647/1191/3273/226/197/374354/2244/7114/81/5265/3309/2335/1/3690/2162/55664/87/5345/3481/54676/2/22915/5473/88/2266/1675/7076/3479/5155/2243/7450/51368/29789/7040/10916/54863/213/5660/801/7057/7043/5627/5054/139322 76 Human_SARS_coronavirus R-HSA-3371556 Cellular response to heat stress 59/2473 89/10654 4.9071672607178384e-18 1.0519739815163866e-16 4.552043314218522e-17 818/3303/6118/4928/6782/815/5903/573/7531/1915/817/5594/3308/84335/10049/348995/1410/10013/79023/472/57122/23636/3313/10808/3305/9261/9532/23279/4927/7415/79902/64223/6119/26353/2932/1387/57805/23225/3309/3320/2033/7266/6767/816/9531/8086/22824/3326/2475/9972/23411/8021/6117/6396/3312/57521/55746/8480/5595 59 Human_SARS_coronavirus R-HSA-2219528 PI3K/AKT Signaling in Cancer 64/2473 101/10654 6.121951113487171e-18 1.292202604262215e-16 5.591547251832817e-17 5295/1147/2308/5170/685/5290/3667/2309/842/3815/572/207/7039/4303/84335/1027/7249/930/3082/941/2064/6199/2260/2100/1950/2263/4233/1026/6714/2099/64223/8503/2932/2261/5159/2247/3164/10000/2534/391/5728/2066/942/208/2885/79109/2475/7409/8660/1385/3932/2931/5293/5155/1956/4254/118788/5296/5781/5156/940/5879/253260/4193 64 Human_SARS_coronavirus R-HSA-4420097 VEGFA-VEGFR2 Pathway 63/2473 99/10654 8.126589678504872e-18 1.6893456119558613e-16 7.310042390234048e-17 5295/26999/5170/5590/4893/857/5290/5335/71/5579/1499/5747/4690/5567/207/7422/5568/3315/3708/57761/5921/1500/9047/9261/3709/10768/6714/64223/5566/1432/10000/3320/2534/9475/3690/4846/3728/5603/998/208/1398/79109/7410/5580/2475/7409/6093/3685/3791/387/3710/60/5296/3845/5600/3265/5058/6300/801/5062/5829/5879/253260 63 Human_SARS_coronavirus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 77/2473 134/10654 1.0385087381297258e-17 2.1266178936029611e-16 9.202182691361592e-17 5295/8454/1147/5718/5170/3725/8945/5601/4893/6464/4773/5290/2205/5335/4790/6885/5682/4772/7321/5707/5336/5532/5594/4775/5717/4214/6500/23118/10892/3708/5705/2206/5530/7316/10213/5970/4792/6850/3709/10768/8915/5714/5701/27040/4067/5602/2534/5534/10454/5702/695/7189/5609/6654/6233/2885/7410/7409/2353/7311/9846/3710/5296/3845/5599/3265/3551/5058/801/6416/5062/997/2207/7314/5879/5595/257397 77 Human_SARS_coronavirus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 30/2473 32/10654 2.4505552908797332e-17 4.944355675127932e-16 2.1394940929662067e-16 57154/51377/25805/10273/5045/9372/64750/7316/5501/56937/4092/4089/11171/23327/867/23645/7046/4088/2280/9958/4087/5499/6233/7514/7048/7311/9110/7040/5500/7314 30 Human_SARS_coronavirus R-HSA-9607240 FLT3 Signaling 124/2473 267/10654 2.794897086764732e-17 5.557389569624945e-16 2.404762710809014e-16 5295/54106/5718/818/5170/815/4893/6464/6711/685/5290/1437/3667/71/5682/5604/2904/3561/5525/5747/153090/3815/5707/5526/8844/10048/817/1849/7010/7039/1439/5594/2322/5717/409/3082/7414/2064/57761/5921/5705/1438/2260/8452/6776/5528/4684/2902/7316/10213/673/9978/1950/3560/2263/4233/3055/3718/5714/6714/5605/5519/10256/2261/5701/27040/5159/3558/3717/2247/2244/2335/2534/3690/408/5529/1445/816/5702/2066/5894/1847/5979/9693/208/6654/6233/5527/2885/6709/3716/88/2266/8660/7311/8826/9846/5518/5155/2243/7450/1956/60/4254/5536/5296/1843/3845/6777/3265/3559/369/801/4763/5781/30849/5245/7529/5156/7314/161742/5595/5515/5516 124 Human_SARS_coronavirus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 26/2473 26/10654 2.91396188610085e-17 5.711365296757666e-16 2.471390231219368e-16 57154/51377/25805/10273/9372/64750/7316/5501/56937/4092/11171/23327/23645/7046/4088/9958/4087/5499/6233/7514/7048/7311/9110/7040/5500/7314 26 Human_SARS_coronavirus R-HSA-166520 Signaling by NTRKs 63/2473 101/10654 3.5147219253387215e-17 6.791828847274263e-16 2.938922410513031e-16 5295/4908/627/1173/9252/4893/6464/5290/3667/5335/4915/5604/2904/1849/5045/5594/1785/160/5528/673/6774/4205/9261/6714/5605/5519/5898/5598/1432/4208/4909/4914/2534/4803/5603/2002/6654/2885/1398/8660/1385/163/6196/5518/1213/387/8851/5296/581/3845/5600/3265/6300/1020/5781/51231/4916/7529/5879/5595/5515/25920/5516 63 Human_SARS_coronavirus R-HSA-72613 Eukaryotic Translation Initiation 70/2473 119/10654 5.72206603413412e-17 1.0661129818380038e-15 4.613224810162915e-16 6158/6144/6203/9349/4736/6206/8891/6194/1965/6191/6128/6132/6147/6129/6217/6222/1983/6152/6136/8667/6125/6141/26986/6202/6232/1967/6134/6169/6175/6218/9669/1964/6193/6210/6231/6229/11224/6205/6130/8890/6142/7458/6204/8663/6228/8894/6124/6207/8893/6233/1975/7311/8664/3646/51386/3921/6188/6189/8665/6135/6201/6187/6208/6157/6137/8892/6122/6133/1968/6230 70 Human_SARS_coronavirus R-HSA-72737 Cap-dependent Translation Initiation 70/2473 119/10654 5.72206603413412e-17 1.0661129818380038e-15 4.613224810162915e-16 6158/6144/6203/9349/4736/6206/8891/6194/1965/6191/6128/6132/6147/6129/6217/6222/1983/6152/6136/8667/6125/6141/26986/6202/6232/1967/6134/6169/6175/6218/9669/1964/6193/6210/6231/6229/11224/6205/6130/8890/6142/7458/6204/8663/6228/8894/6124/6207/8893/6233/1975/7311/8664/3646/51386/3921/6188/6189/8665/6135/6201/6187/6208/6157/6137/8892/6122/6133/1968/6230 70 Human_SARS_coronavirus R-HSA-9006931 Signaling by Nuclear Receptors 134/2473 299/10654 5.750172059476115e-17 1.0661129818380038e-15 4.613224810162915e-16 5295/3727/5170/27161/3725/2354/2963/3838/596/5434/5440/5590/4893/6464/8841/685/857/5290/1374/79718/5241/4316/2309/4435/9687/5747/59345/5160/8204/5430/2770/207/5436/5451/7039/2625/57690/5594/6722/1027/3315/27327/10274/51523/5915/4318/5441/10735/192670/5438/5431/5885/2100/5435/4313/5433/1950/9611/1509/865/5469/2874/1655/2194/4314/9612/6667/7033/6714/2099/4609/2962/8850/8503/10524/1387/5346/5437/2171/5467/6907/10000/3320/2033/8243/4846/9126/595/2783/8312/2782/5439/192669/3065/2002/2066/861/23028/6256/23112/208/10498/3326/7514/1385/1025/2353/1738/10499/1386/6908/1956/5536/3169/5296/4343/3845/858/904/3276/3265/26523/23189/801/8202/5432/8648/3480/2773/2957/10062/5595/7528/6387 134 Human_SARS_coronavirus R-HSA-194138 Signaling by VEGF 65/2473 107/10654 7.68429072092681e-17 1.4057129158815444e-15 6.0827227601441705e-16 5295/26999/5170/5590/4893/857/5290/5335/71/5579/1499/5747/4690/5567/7424/207/7422/5568/3315/3708/57761/5921/1500/9047/7423/9261/3709/10768/6714/64223/5566/1432/10000/3320/2534/9475/3690/4846/3728/5603/998/208/1398/79109/7410/5580/2475/7409/6093/3685/3791/387/3710/60/5296/3845/5600/3265/5058/6300/801/5062/5829/5879/253260 65 Human_SARS_coronavirus R-HSA-448424 Interleukin-17 signaling 50/2473 72/10654 8.90641328239126e-17 1.6078419767685277e-15 6.95736439233888e-16 8454/3605/1147/3725/8945/1326/5601/9252/4790/6885/5606/5604/1849/5594/6500/23118/5528/7316/79155/4205/9261/5519/5598/1432/4208/5602/10454/2002/3654/7189/112744/5609/6233/1385/2353/7311/6196/5518/1386/5599/5600/3551/6416/5608/51231/7314/5595/5515/257397/5516 50 Human_SARS_coronavirus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 57/2473 88/10654 9.092442444118757e-17 1.6201079264066147e-15 7.01044092752287e-16 8454/115106/8945/55559/22981/7531/10142/4659/203068/54801/7532/84962/1454/10382/95681/6500/121441/7277/79441/9133/5116/5048/1781/23354/7316/891/8655/9738/983/1639/6790/5566/84131/7283/3320/22919/79866/4751/5577/6233/7311/54930/5518/10383/54820/5347/9662/55142/23332/1453/9793/4660/93323/55755/5500/7314/1778 57 Human_SARS_coronavirus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 114/2473 244/10654 3.204517024934729e-16 5.636663279756986e-15 2.439065589828863e-15 10450/7536/10921/8449/23451/7919/53981/4928/2963/5434/5440/5903/55599/6432/6431/10084/8563/6430/6627/5430/79869/4904/5436/10523/9128/25804/51690/29894/27238/3178/23450/348995/79023/57122/5441/23636/3183/5438/85313/5431/5093/22794/81608/5435/10594/4686/8189/6625/5433/11338/1655/9343/29107/3190/65109/6626/56339/5546/1478/23279/4927/10181/79902/2962/10898/22938/988/5437/10250/6629/4670/10569/23225/10189/9295/10482/51692/55660/5439/10421/51729/1660/23283/8086/3191/9410/57794/57721/9972/23524/6634/10914/51593/8021/9775/3192/57187/6396/6427/3312/8175/5356/2733/6426/84950/84991/5432/55746/22916/1479/26121/8480/55339/1994 114 Human_SARS_coronavirus R-HSA-9614085 FOXO-mediated transcription 46/2473 65/10654 4.80837764239373e-16 8.350752057423035e-15 3.613490993084695e-15 2308/27113/857/2290/2309/65018/10018/4802/2660/356/7532/207/10971/4303/1027/7295/2810/4287/1649/7534/5934/4800/5443/1026/4089/8850/1647/9314/10370/1387/4088/2908/10628/10000/6794/2033/3630/3066/3065/6648/4087/208/604/23411/25942/7529 46 Human_SARS_coronavirus R-HSA-69275 G2/M Transition 97/2473 196/10654 5.236157986597025e-16 8.863678414069388e-15 3.835441633830854e-15 10844/8454/115106/5718/1017/8945/55559/994/2305/5682/22981/7531/51512/10142/4659/5707/203068/54801/7532/84962/63943/1454/10382/1063/347688/95681/5717/6500/121441/7277/79441/9133/10381/5705/5116/286826/5048/1781/23354/7316/10213/728642/9978/891/993/890/8655/9738/983/1026/1639/6790/5714/5566/5519/84131/5928/5701/7283/3320/22919/2033/995/10376/10426/5702/5520/7157/8900/79866/4751/5577/6233/3326/28227/55957/7514/7311/54930/5518/10383/54820/5347/9662/55142/23332/1453/7465/9793/4660/93323/55755/5500/7314/5515/1778/5516 97 Human_SARS_coronavirus R-HSA-927802 Nonsense-Mediated Decay (NMD) 67/2473 115/10654 5.297533746018147e-16 8.863678414069388e-15 3.835441633830854e-15 10921/6158/9887/6144/6203/9349/4736/6206/6194/2107/6191/6128/6132/6147/6129/6217/6222/6152/6136/6125/6141/26986/6202/6232/26019/2935/6134/6169/22794/4686/6175/6218/65109/6193/6210/6231/6229/11224/6205/6130/6142/6204/6228/55802/6124/5520/6207/6233/7311/5518/3921/6188/6189/9775/6135/6201/5976/6187/65110/22916/6208/6157/6137/6122/6133/5515/6230 67 Human_SARS_coronavirus R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 67/2473 115/10654 5.297533746018147e-16 8.863678414069388e-15 3.835441633830854e-15 10921/6158/9887/6144/6203/9349/4736/6206/6194/2107/6191/6128/6132/6147/6129/6217/6222/6152/6136/6125/6141/26986/6202/6232/26019/2935/6134/6169/22794/4686/6175/6218/65109/6193/6210/6231/6229/11224/6205/6130/6142/6204/6228/55802/6124/5520/6207/6233/7311/5518/3921/6188/6189/9775/6135/6201/5976/6187/65110/22916/6208/6157/6137/6122/6133/5515/6230 67 Human_SARS_coronavirus R-HSA-5684996 MAPK1/MAPK3 signaling 117/2473 255/10654 6.929220653544943e-16 1.1454085224895978e-14 4.956348064171653e-15 5718/818/815/4893/6464/6711/685/1437/3667/71/5682/5604/2904/3561/5525/5747/153090/3815/5707/5526/8844/10048/817/1849/7010/7039/1439/5594/2322/5717/409/3082/7414/2064/5921/5705/1438/2260/8452/5528/4684/2902/7316/10213/673/9978/1950/3560/2263/4233/983/3718/5714/6714/5605/5519/10256/2261/5701/27040/5159/3558/3717/2247/2244/2335/2534/3690/408/5529/1445/816/5702/2066/5894/1847/5979/9693/6654/6233/5527/2885/6709/3716/88/2266/8660/7311/8826/5518/5155/2243/7450/1956/60/4254/5536/1843/3570/3845/3265/3559/369/801/4763/7297/5781/3569/5245/7529/5156/7314/3572/161742/5595/5515/5516 117 Human_SARS_coronavirus R-HSA-2871796 FCERI mediated MAPK activation 29/2473 32/10654 8.289545478412574e-16 1.3539590948073871e-14 5.858776503539714e-15 3725/5601/4893/6464/2205/5335/5336/5594/4214/2206/6850/27040/4067/5602/5609/6654/2885/7410/7409/2353/3845/5599/3265/5058/6416/5062/2207/5879/5595 29 Human_SARS_coronavirus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 37/2473 47/10654 1.1421635257976261e-015 1.843586302816874e-14 7.977464130648436e-15 8454/8841/79718/2648/9734/892/23462/51564/3280/6500/3091/10013/7316/9978/9611/9759/9612/1024/4609/10014/22938/8850/1387/6907/26508/2033/55294/3066/3065/7088/9794/6233/7311/388585/3516/4851/7314 37 Human_SARS_coronavirus R-HSA-453274 Mitotic G2-G2/M phases 97/2473 198/10654 1.2179923181943148e-15 1.9431226285611627e-14 8.408172184352431e-15 10844/8454/115106/5718/1017/8945/55559/994/2305/5682/22981/7531/51512/10142/4659/5707/203068/54801/7532/84962/63943/1454/10382/1063/347688/95681/5717/6500/121441/7277/79441/9133/10381/5705/5116/286826/5048/1781/23354/7316/10213/728642/9978/891/993/890/8655/9738/983/1026/1639/6790/5714/5566/5519/84131/5928/5701/7283/3320/22919/2033/995/10376/10426/5702/5520/7157/8900/79866/4751/5577/6233/3326/28227/55957/7514/7311/54930/5518/10383/54820/5347/9662/55142/23332/1453/7465/9793/4660/93323/55755/5500/7314/5515/1778/5516 97 Human_SARS_coronavirus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 65/2473 112/10654 1.890199337875547e-15 2.9808660822589085e-14 1.2898637949931138e-14 5295/8454/1147/5718/5777/8945/4893/4773/4790/6885/5579/5966/5682/4690/4772/5707/5336/640/5532/4775/5717/6500/930/10892/3708/5705/5530/7220/7316/10213/5970/4792/6850/3709/10768/4793/8915/5714/5701/4067/29760/2534/5534/5702/2280/695/974/6654/30011/6233/2885/7409/7311/5293/3710/118788/4794/3845/27071/3265/3551/801/973/933/7314 65 Human_SARS_coronavirus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 23/2473 23/10654 2.382963409403529e-15 3.6786409311253587e-14 1.591801047379701e-14 7321/6497/51592/64750/7323/8239/54778/7316/9611/9612/4089/60436/23327/7050/4088/142/5494/3065/6498/4087/6233/7311/7314 23 Human_SARS_coronavirus R-HSA-162587 HIV Life Cycle 80/2473 152/10654 2.3862903999282573e-15 3.6786409311253587e-14 1.591801047379701e-14 6884/137492/5905/51652/4928/2963/5434/5440/5903/7852/3159/25978/51160/2959/5430/27243/6874/5436/5045/6749/348995/79023/57122/5441/23636/91782/5438/5431/79720/5435/4686/7316/5433/6872/2960/4836/9397/51271/23279/4927/79902/9150/2962/23327/5437/8812/23225/905/2068/5439/5902/5901/8086/6873/3836/6233/7514/1025/7311/9972/93343/6908/8021/7251/6396/904/6883/1104/51497/2547/2961/5432/55746/22916/1234/8480/92421/2957/7314/25920 80 Human_SARS_coronavirus R-HSA-162599 Late Phase of HIV Life Cycle 75/2473 139/10654 3.0765390938255714e-15 4.690012929698537e-14 2.029436314523535e-14 6884/137492/5905/51652/4928/2963/5434/5440/5903/25978/51160/2959/5430/27243/6874/5436/5045/6749/348995/79023/57122/5441/23636/91782/5438/5431/79720/5435/4686/7316/5433/6872/2960/4836/9397/51271/23279/4927/79902/9150/2962/23327/5437/8812/23225/905/2068/5439/5902/5901/8086/6873/6233/7514/1025/7311/9972/93343/6908/8021/7251/6396/904/6883/1104/51497/2961/5432/55746/22916/8480/92421/2957/7314/25920 75 Human_SARS_coronavirus R-HSA-376176 Signaling by ROBO receptors 103/2473 218/10654 3.5109771965261708e-15 5.293473311685611e-14 2.290562335269821e-14 10921/6158/5718/6144/25/55740/6203/9349/4736/7852/6206/6194/2107/6191/6128/5682/6132/2817/6147/10298/6129/4690/6217/5707/5567/89884/6222/6152/6136/5532/5568/6125/5717/27/6141/26986/23053/6202/5705/3670/6232/26019/2935/6134/6169/22794/23122/4686/7316/10213/6175/9978/6218/65109/5714/6193/6714/6210/6231/6229/11224/6205/5566/6130/6142/6204/5701/6228/5576/1605/51466/7408/6124/5702/998/8453/6207/6654/6233/7311/387/3921/6188/6189/9775/5217/6135/6201/23332/5058/6187/65110/5062/22916/6208/6157/6137/6122/6133/7314/5879/6387/6230 103 Human_SARS_coronavirus R-HSA-451927 Interleukin-2 family signaling 35/2473 44/10654 3.829626804198634e-15 5.711139103652744e-14 2.4712923541968306e-14 5295/5777/3635/6464/5290/1437/3561/3578/6775/1439/1438/3581/6776/3560/50615/6774/6850/3718/6772/8503/3558/3717/3636/6654/2885/3716/9846/3932/5293/5296/6777/3600/3559/3601/59067 35 Human_SARS_coronavirus R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 64/2473 112/10654 8.728227714212304e-15 1.2876482176235786e-13 5.571839763232303e-14 6158/6144/6203/9349/4736/6206/6194/1965/6191/6128/6132/6147/6129/6217/6222/1983/6152/6136/8667/6125/6141/6202/6232/6134/6169/6175/6218/9669/1964/6193/6210/6231/6229/11224/6205/6130/6142/7458/6204/8663/6228/8894/6124/6207/6233/1975/7311/8664/3646/51386/3921/6188/6189/8665/6135/6201/6187/6208/6157/6137/6122/6133/1968/6230 64 Human_SARS_coronavirus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 24/2473 25/10654 1.0692810455283975e-14 1.5606953132605974e-13 6.753353971758301e-14 1147/2308/5170/2309/842/572/207/4303/84335/1027/7249/6199/1026/64223/2932/3164/10000/208/79109/2475/1385/2931/253260/4193 24 Human_SARS_coronavirus R-HSA-114452 Activation of BH3-only proteins 27/2473 30/10654 1.28327812230538e-14 1.853323772424191e-13 8.019599567648027e-14 23368/27113/596/10018/7531/7027/572/7532/207/10971/7533/2810/7534/8655/5366/10000/5534/7157/90427/8626/208/7161/5599/7159/637/140735/7529 27 Human_SARS_coronavirus R-HSA-1433557 Signaling by SCF-KIT 34/2473 43/10654 1.3283329702558361e-14 1.8984092033239656e-13 8.21469073710846e-14 5295/5777/4893/5290/3815/4318/6776/9306/6774/6772/6714/8651/8503/867/4067/3717/2534/1111/6654/2885/7525/7409/9846/3932/4254/5296/3845/10076/6777/3265/5781/5879/2887/2242 34 Human_SARS_coronavirus R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 63/2473 111/10654 2.1914637858788164e-14 3.0996786744595216e-13 1.3412757191922437e-13 6158/6144/6203/9349/4736/6206/6194/1965/6191/6128/6132/6147/6129/6217/6222/6152/6136/8667/6125/6141/26986/6202/6232/6134/6169/6175/6218/1964/6193/6210/6231/6229/11224/6205/6130/6142/7458/6204/8663/6228/8894/6124/6207/6233/1975/7311/8664/3646/51386/3921/6188/6189/8665/6135/6201/6187/6208/6157/6137/6122/6133/1968/6230 63 Human_SARS_coronavirus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 53/2473 86/10654 2.374963634946151e-14 3.3249490889246117e-13 1.438753480246648e-13 5295/26999/25/5290/23646/5335/71/51517/5747/4690/4651/10093/5336/4627/4771/5594/2268/3708/919/3055/6850/10552/3709/10768/10094/4641/6714/4067/917/3320/2534/998/695/8976/2885/7525/1398/7410/10096/3326/5580/10097/7409/3710/60/5296/5581/5338/10095/5058/10109/5879/5595 53 Human_SARS_coronavirus R-HSA-72163 mRNA Splicing - Major Pathway 89/2473 183/10654 3.211943487319474e-14 4.4512994591942606e-13 1.9261415490145488e-13 10450/7536/10921/8449/23451/53981/2963/5434/5440/6432/6431/10084/6430/6627/5430/79869/4904/5436/10523/9128/25804/51690/29894/27238/3178/23450/5441/3183/5438/85313/5431/5093/22794/81608/5435/10594/4686/8189/6625/5433/11338/1655/9343/3190/65109/6626/5546/1478/10181/2962/10898/22938/988/5437/10250/6629/4670/10569/10189/9295/51692/55660/5439/10421/51729/1660/23283/3191/9410/57794/23524/6634/10914/51593/9775/3192/6427/3312/8175/5356/6426/84950/84991/5432/22916/1479/26121/55339/1994 89 Human_SARS_coronavirus R-HSA-9009391 Extra-nuclear estrogen signaling 49/2473 77/10654 3.7281831699341965e-14 5.115067309149718e-13 2.2133634819398809e-13 5295/5170/596/5590/4893/6464/685/857/5290/4316/2309/5747/59345/2770/207/7039/5594/6722/1027/3315/4318/2100/4313/1950/4314/6714/2099/8503/10000/3320/4846/595/2783/2782/2002/208/7514/1385/2353/1956/5296/3845/858/3276/3265/801/3480/2773/5595 49 Human_SARS_coronavirus R-HSA-2559583 Cellular Senescence 93/2473 195/10654 3.8394679636451676e-14 5.193825812221762e-13 2.2474434234257126e-13 1912/1017/7014/3725/1019/5601/2077/4790/5606/9448/3159/7290/1029/7027/7321/2146/8535/6045/8697/57690/5594/1027/27327/80012/5931/7295/5925/7013/1051/472/192670/3576/3490/8881/29855/7316/2114/890/6774/5970/1026/9261/1911/6667/51433/4194/5598/3552/5928/1432/10524/84733/5602/65057/23512/57332/25842/192669/7157/8900/23135/29945/10393/8091/23112/5609/6233/51434/2353/1030/7311/6196/3397/4343/8726/29882/5599/5600/23466/4217/26523/3456/2113/6416/5608/54386/3569/7314/996/6015/5595/4193/23043 93 Human_SARS_coronavirus R-HSA-388841 Costimulation by the CD28 family 46/2473 70/10654 3.8612990732260915e-14 5.193825812221762e-13 2.2474434234257126e-13 5295/5170/5777/1326/5290/5525/5526/207/941/57761/919/5528/6714/64223/5519/8503/29126/4067/915/917/10000/2534/5529/1445/916/998/942/208/5527/2885/7525/79109/2475/7409/3932/5518/5296/5058/5781/5062/1493/940/5879/253260/5515/5516 46 Human_SARS_coronavirus R-HSA-389513 CTLA4 inhibitory signaling 21/2473 21/10654 4.482542113832761e-14 5.970920174930629e-13 2.583703374758996e-13 5525/5526/207/941/5528/6714/5519/4067/10000/2534/5529/942/208/5527/7525/3932/5518/5781/1493/5515/5516 21 Human_SARS_coronavirus R-HSA-5673001 RAF/MAP kinase cascade 111/2473 249/10654 4.551537582689891e-14 6.00452842639474e-13 2.5982461504424074e-13 5718/818/815/4893/6464/6711/685/1437/3667/71/5682/5604/2904/3561/5525/5747/153090/3815/5707/5526/8844/10048/817/1849/7010/7039/1439/5594/2322/5717/409/3082/7414/2064/5921/5705/1438/2260/8452/5528/4684/2902/7316/10213/673/9978/1950/3560/2263/4233/3718/5714/6714/5605/5519/10256/2261/5701/27040/5159/3558/3717/2247/2244/2335/2534/3690/408/5529/1445/816/5702/2066/5894/1847/5979/9693/6654/6233/5527/2885/6709/3716/88/2266/8660/7311/8826/5518/5155/2243/7450/1956/60/4254/5536/1843/3845/3265/3559/369/801/4763/5245/7529/5156/7314/161742/5595/5515/5516 111 Human_SARS_coronavirus R-HSA-199418 Negative regulation of the PI3K/AKT network 62/2473 110/10654 5.4642010881527177e-14 7.139889421852885e-13 3.089533246835221e-13 5295/3643/685/5290/3667/90865/5525/3815/5526/207/7039/5594/930/3082/941/2064/57761/2260/4615/5528/2100/1950/2263/4233/6714/2099/5519/8503/2261/5159/2247/10000/2534/391/5728/5529/3630/2066/942/3654/7189/208/5527/2885/7409/8660/3932/5293/5518/5155/1956/4254/118788/5296/5781/5156/940/5879/5595/5515/3556/5516 62 Human_SARS_coronavirus R-HSA-187037 Signaling by NTRK1 (TRKA) 50/2473 80/10654 5.811463711651671e-14 7.52200774753405e-13 3.254881363824769e-13 5295/1173/9252/4893/6464/5290/3667/5335/4915/5604/1849/5594/1785/160/5528/673/6774/4205/9261/6714/5605/5519/5898/5598/1432/4208/4914/4803/5603/2002/6654/2885/1398/8660/1385/163/6196/5518/1213/387/5296/3845/5600/3265/6300/51231/7529/5595/5515/5516 50 Human_SARS_coronavirus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 56/2473 95/10654 6.714573695634487e-14 8.609715056458426e-13 3.725548021975259e-13 6158/6144/6203/9349/4736/6206/6194/2107/6191/6128/6132/6147/6129/6217/6222/6152/6136/6125/6141/26986/6202/6232/2935/6134/6169/4686/6175/6218/6193/6210/6231/6229/11224/6205/6130/6142/6204/6228/6124/6207/6233/7311/3921/6188/6189/6135/6201/5976/6187/22916/6208/6157/6137/6122/6133/6230 56 Human_SARS_coronavirus R-HSA-446652 Interleukin-1 family signaling 73/2473 140/10654 7.530043595162042e-14 9.56594427089104e-13 4.1393222102060356e-13 8454/3557/1147/5778/5718/834/5777/8945/1326/351/4790/6885/5682/90865/5604/4215/26469/5782/5783/5707/27178/29110/3553/8878/54472/5717/6500/23118/25930/5705/4615/7316/3565/10213/9978/79155/6774/5970/4792/5780/59307/4793/5714/3606/8809/5775/3146/3552/5701/4088/84867/57162/5771/10454/6288/5702/3654/7189/6233/7311/5599/5784/3551/7850/6416/5781/5608/4791/3554/7314/3596/257397/3556 73 Human_SARS_coronavirus R-HSA-5633007 Regulation of TP53 Activity 80/2473 160/10654 9.644098332845622e-14 1.2139176984095591e-12 5.25279716052625e-13 23368/6884/1017/6118/5170/3622/5883/1029/1459/9219/6874/207/9212/5931/1460/6749/472/639/7316/6872/28996/890/1457/54971/983/6790/641/1108/64223/4194/5519/6119/5928/1432/5571/10524/10848/57459/1616/10000/6794/54815/2033/1111/3066/3065/7157/1107/8900/8626/6873/5371/208/6233/5527/79109/2475/672/7311/7161/5562/5518/6908/8851/5300/6117/5600/7159/6883/7874/1020/5608/53615/26155/7314/253260/4193/5515/1263/5516 80 Human_SARS_coronavirus R-HSA-389356 CD28 co-stimulation 28/2473 33/10654 1.0443359338930247e-13 1.290836848019126e-12 5.585637427365254e-13 5295/5170/1326/5290/207/941/57761/6714/64223/8503/4067/10000/2534/998/942/208/2885/7525/79109/2475/7409/3932/5296/5058/5062/940/5879/253260 28 Human_SARS_coronavirus R-HSA-9022692 Regulation of MECP2 expression and activity 28/2473 33/10654 1.0443359338930247e-13 1.290836848019126e-12 5.585637427365254e-13 818/27161/815/8841/2290/79718/817/9212/3930/57690/27327/192670/9611/28996/2874/9612/5566/6907/816/192669/3066/3065/23112/1385/25942/4343/26523/801 28 Human_SARS_coronavirus R-HSA-72172 mRNA Splicing 90/2473 191/10654 2.411992491327395e-13 2.954690801876059e-12 1.2785373732224161e-12 10450/7536/10921/8449/23451/53981/2963/5434/5440/55599/6432/6431/10084/6430/6627/5430/79869/4904/5436/10523/9128/25804/51690/29894/27238/3178/23450/5441/3183/5438/85313/5431/5093/22794/81608/5435/10594/4686/8189/6625/5433/11338/1655/9343/3190/65109/6626/5546/1478/10181/2962/10898/22938/988/5437/10250/6629/4670/10569/10189/9295/51692/55660/5439/10421/51729/1660/23283/3191/9410/57794/23524/6634/10914/51593/9775/3192/6427/3312/8175/5356/6426/84950/84991/5432/22916/1479/26121/55339/1994 90 Human_SARS_coronavirus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 58/2473 103/10654 3.766431069645255e-13 4.5730472810206105e-12 1.9788235894549827e-12 5295/3643/685/5290/3667/90865/5525/3815/5526/207/7039/5594/930/3082/941/2064/2260/4615/5528/2100/1950/2263/4233/6714/2099/5519/8503/2261/5159/2247/2534/391/5529/3630/2066/942/3654/7189/5527/2885/7409/8660/3932/5293/5518/5155/1956/4254/118788/5296/5781/5156/940/5879/5595/5515/3556/5516 58 Human_SARS_coronavirus R-HSA-5673000 RAF activation 27/2473 32/10654 3.8553623091131926e-13 4.599614859220261e-12 1.990319764155461e-12 818/815/4893/5604/5525/5526/8844/817/5528/673/6714/5605/5519/3717/5529/816/5894/5527/5518/3845/3265/369/801/5245/7529/5515/5516 27 Human_SARS_coronavirus R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 27/2473 32/10654 3.8553623091131926e-13 4.599614859220261e-12 1.990319764155461e-12 5295/5777/4690/5336/640/930/3708/7220/6850/3709/10768/4067/29760/2534/695/974/6654/30011/2885/7409/5293/3710/118788/27071/801/973/933 27 Human_SARS_coronavirus R-HSA-156842 Eukaryotic Translation Elongation 54/2473 93/10654 4.4566268309910897e-13 5.2711138035515306e-12 2.2808870532477085e-12 6158/6144/6203/9349/4736/6206/6194/6191/6128/6132/1938/6147/6129/1915/6217/1936/6222/6152/6136/6125/6141/6202/6232/6134/6169/6175/6218/1933/6193/6210/6231/6229/11224/6205/6130/6142/6204/6228/6124/6207/6233/7311/3921/6188/6189/6135/6201/6187/6208/6157/6137/6122/6133/6230 54 Human_SARS_coronavirus R-HSA-72689 Formation of a pool of free 40S subunits 57/2473 101/10654 5.292121228805392e-13 6.205803697368374e-12 2.685340866438364e-12 6158/6144/6203/9349/4736/6206/6194/6191/6128/6132/6147/6129/6217/6222/6152/6136/8667/6125/6141/6202/6232/6134/6169/6175/6218/1964/6193/6210/6231/6229/11224/6205/6130/6142/6204/8663/6228/6124/6207/6233/7311/8664/3646/51386/3921/6188/6189/8665/6135/6201/6187/6208/6157/6137/6122/6133/6230 57 Human_SARS_coronavirus R-HSA-9018519 Estrogen-dependent gene expression 75/2473 150/10654 5.737060336591778e-13 6.6705481201728125e-12 2.886442488704516e-12 3727/27161/3725/2354/2963/3838/596/5434/5440/5241/4435/9687/8204/5430/5436/5451/7039/2625/57690/27327/10274/51523/5441/10735/192670/5438/5431/5885/5435/5433/1509/865/5469/1655/6667/7033/2099/4609/2962/8850/10524/1387/5437/3320/2033/8243/9126/595/8312/5439/192669/3065/2066/861/23028/23112/10498/3326/1025/2353/10499/1386/6908/3169/4343/904/3276/26523/23189/8202/5432/8648/2957/7528/6387 75 Human_SARS_coronavirus R-HSA-156902 Peptide chain elongation 52/2473 89/10654 8.610646724435978e-13 9.927569164643833e-12 4.295802523292253e-12 6158/6144/6203/9349/4736/6206/6194/6191/6128/6132/1938/6147/6129/1915/6217/6222/6152/6136/6125/6141/6202/6232/6134/6169/6175/6218/6193/6210/6231/6229/11224/6205/6130/6142/6204/6228/6124/6207/6233/7311/3921/6188/6189/6135/6201/6187/6208/6157/6137/6122/6133/6230 52 Human_SARS_coronavirus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 34/2473 47/10654 1.209548887208375e-12 1.3491878644308053e-11 5.838130700774699e-12 818/815/4893/71/5604/8844/817/5594/409/7414/673/6714/5605/10256/3717/2244/2335/3690/408/1445/816/5894/2266/8826/2243/7450/60/3845/3265/369/801/5245/7529/5595 34 Human_SARS_coronavirus R-HSA-6802949 Signaling by RAS mutants 34/2473 47/10654 1.209548887208375e-12 1.3491878644308053e-11 5.838130700774699e-12 818/815/4893/71/5604/8844/817/5594/409/7414/673/6714/5605/10256/3717/2244/2335/3690/408/1445/816/5894/2266/8826/2243/7450/60/3845/3265/369/801/5245/7529/5595 34 Human_SARS_coronavirus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 34/2473 47/10654 1.209548887208375e-12 1.3491878644308053e-11 5.838130700774699e-12 818/815/4893/71/5604/8844/817/5594/409/7414/673/6714/5605/10256/3717/2244/2335/3690/408/1445/816/5894/2266/8826/2243/7450/60/3845/3265/369/801/5245/7529/5595 34 Human_SARS_coronavirus R-HSA-9649948 Signaling downstream of RAS mutants 34/2473 47/10654 1.209548887208375e-12 1.3491878644308053e-11 5.838130700774699e-12 818/815/4893/71/5604/8844/817/5594/409/7414/673/6714/5605/10256/3717/2244/2335/3690/408/1445/816/5894/2266/8826/2243/7450/60/3845/3265/369/801/5245/7529/5595 34 Human_SARS_coronavirus R-HSA-3899300 SUMOylation of transcription cofactors 33/2473 45/10654 1.3877072087054698e-12 1.5354308793096005e-11 6.64403111808052e-12 1912/1487/3622/8204/8535/6045/51588/4869/80012/6613/28996/1655/9612/1911/9994/7341/1387/84733/10401/10521/1616/2033/57332/7329/115426/10155/10499/9063/25942/11315/8648/6015/8554 33 Human_SARS_coronavirus R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 26/2473 31/10654 1.4150947442119051e-12 1.5532079912469873e-11 6.72095524829907e-12 857/1499/5525/139285/1856/5526/1452/4041/7471/5528/23401/89780/5519/2932/1455/324/8312/5529/1855/5527/1857/4040/5518/7855/5515/5516 26 Human_SARS_coronavirus R-HSA-1226099 Signaling by FGFR in disease 41/2473 63/10654 1.542089843660862e-12 1.6791644964307164e-11 7.265987233289276e-12 5295/2963/8805/5434/5440/4893/11052/26127/5290/5335/5430/5436/613/5441/2260/5438/9208/5431/6776/5435/4686/5433/6774/2263/6772/2962/399687/2261/5437/2247/5439/6654/2885/9846/3845/6777/3265/5432/22916/7750/1523 41 Human_SARS_coronavirus R-HSA-982772 Growth hormone receptor signaling 22/2473 24/10654 1.7337121031666943e-12 1.8729551224761454e-11 8.104547253924705e-12 5777/3667/5770/2690/9021/5594/6776/6774/6772/8651/1442/4067/3717/5618/2688/8660/1154/5617/8835/6777/2689/5595 22 Human_SARS_coronavirus R-HSA-6806003 Regulation of TP53 Expression and Degradation 29/2473 37/10654 1.8381345320533547e-12 1.9702504515446895e-11 8.525558191431679e-12 1017/5170/1029/207/472/639/7316/890/983/64223/4194/5519/1616/10000/7157/8900/208/6233/5527/79109/2475/7311/5518/7874/7314/253260/4193/5515/5516 29 Human_SARS_coronavirus R-HSA-1227986 Signaling by ERBB2 35/2473 50/10654 2.679220367061098e-12 2.8495273981456017e-11 1.2330316499571273e-11 5295/4893/8065/6464/685/5290/5335/26469/5782/10273/207/9101/2064/7316/1950/5753/6714/10000/3320/2534/2066/208/6654/6233/2885/7525/5580/7311/387/1956/5581/3845/3265/11140/7314 35 Human_SARS_coronavirus R-HSA-8986944 Transcriptional Regulation by MECP2 40/2473 62/10654 4.388559732031371e-12 4.613744402457095e-11 1.9964338215327616e-11 818/27161/627/815/8841/2290/79718/5770/5468/2904/817/9212/3930/57690/27327/6657/192670/9611/28996/2874/4233/9612/5775/5566/4988/4208/2903/6907/5728/816/192669/3066/3065/3654/23112/1385/25942/4343/26523/801 40 Human_SARS_coronavirus R-HSA-69231 Cyclin D associated events in G1 32/2473 44/10654 4.438879454259012e-12 4.613744402457095e-11 1.9964338215327616e-11 8454/25/894/1019/1029/7027/1027/6500/5925/5934/7316/5753/1875/1026/5933/6714/5519/4067/3717/6502/1874/595/5520/896/6233/28227/1030/7311/5518/7314/5515/5516 32 Human_SARS_coronavirus R-HSA-69236 G1 Phase 32/2473 44/10654 4.438879454259012e-12 4.613744402457095e-11 1.9964338215327616e-11 8454/25/894/1019/1029/7027/1027/6500/5925/5934/7316/5753/1875/1026/5933/6714/5519/4067/3717/6502/1874/595/5520/896/6233/28227/1030/7311/5518/7314/5515/5516 32 Human_SARS_coronavirus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 25/2473 30/10654 5.162222119509663e-12 5.325239660125758e-11 2.3043080929192325e-11 7124/1147/81858/7186/56957/6885/8737/55072/7375/330/23118/27005/7316/7128/7132/329/10454/6233/7311/331/8717/1540/3551/7314/257397 25 Human_SARS_coronavirus R-HSA-73887 Death Receptor Signalling 70/2473 141/10654 5.2492844855727465e-12 5.374640532989409e-11 2.3256845639143987e-11 7124/1147/4804/57142/81858/84888/8841/7186/56957/4790/6885/5584/10018/7531/572/8737/57580/55072/356/7375/835/8878/1894/355/330/23421/23118/841/27005/23370/4615/7316/50650/5970/4792/5664/8797/7128/7132/329/9138/836/8837/4803/11108/10454/3066/3065/55512/8567/3654/7189/6654/6233/7410/7409/7311/26574/387/8772/331/5599/8717/1540/3551/8795/5663/7314/5879/257397 70 Human_SARS_coronavirus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 46/2473 77/10654 6.008301996946257e-12 6.106215066526122e-11 2.6422474278968336e-11 1912/4928/5903/1029/8535/51564/6045/51588/80012/10274/348995/79023/6613/57122/23636/10735/5885/6996/1911/641/23137/23279/4927/79902/9656/7341/84733/23225/8243/9126/57332/142/8086/7329/5371/8924/672/9972/9063/8021/6117/6396/55746/8480/6015/8554 46 Human_SARS_coronavirus R-HSA-6804757 Regulation of TP53 Degradation 28/2473 36/10654 6.274988070110376e-12 6.330355611905467e-11 2.739236278283477e-11 1017/5170/1029/207/472/7316/890/983/64223/4194/5519/1616/10000/7157/8900/208/6233/5527/79109/2475/7311/5518/7874/7314/253260/4193/5515/5516 28 Human_SARS_coronavirus R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 35/2473 51/10654 6.638273096766927e-12 6.647964006397244e-11 2.8766700165782155e-11 6203/6206/6194/1965/6191/6217/6222/8667/6202/6232/6218/1964/6193/6210/6231/6229/6205/6204/8663/6228/8894/6207/6233/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1968/6230 35 Human_SARS_coronavirus R-HSA-72649 Translation initiation complex formation 38/2473 58/10654 7.479265833683952e-12 7.382412031521139e-11 3.194476281861226e-11 6203/6206/6194/1965/6191/6217/6222/8667/26986/6202/6232/6218/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/6207/6233/1975/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1968/6230 38 Human_SARS_coronavirus R-HSA-72702 Ribosomal scanning and start codon recognition 38/2473 58/10654 7.479265833683952e-12 7.382412031521139e-11 3.194476281861226e-11 6203/6206/6194/1965/6191/6217/6222/1983/8667/6202/6232/6218/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/6207/6233/1975/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1968/6230 38 Human_SARS_coronavirus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 34/2473 49/10654 8.18728697085617e-12 8.023541231439048e-11 3.471902144032241e-11 1017/7027/7832/4849/1027/4869/4850/2810/5934/891/890/10769/983/1026/6790/5933/5111/1647/4848/23019/28984/2033/995/1874/7157/8900/10498/55571/5325/581/3276/85456/29883/1263 34 Human_SARS_coronavirus R-HSA-2408557 Selenocysteine synthesis 52/2473 93/10654 9.014508365418089e-12 8.709792589685646e-11 3.768853015638104e-11 6158/6144/6203/9349/4736/6206/6194/6191/6128/6132/6147/6129/6217/6222/6152/6136/6125/6141/6202/6232/6134/6169/6175/6218/79048/6193/6210/6231/6229/11224/6205/6130/6142/6204/6228/6124/6207/6233/51091/7311/3921/6188/6189/6135/6201/6187/6208/6157/6137/6122/6133/6230 52 Human_SARS_coronavirus R-HSA-72764 Eukaryotic Translation Termination 52/2473 93/10654 9.014508365418089e-12 8.709792589685646e-11 3.768853015638104e-11 6158/6144/6203/9349/4736/6206/6194/2107/6191/6128/6132/6147/6129/6217/6222/6152/6136/6125/6141/6202/6232/2935/6134/6169/6175/6218/6193/6210/6231/6229/11224/6205/6130/6142/6204/6228/6124/6207/6233/7311/3921/6188/6189/6135/6201/6187/6208/6157/6137/6122/6133/6230 52 Human_SARS_coronavirus R-HSA-8878159 Transcriptional regulation by RUNX3 53/2473 96/10654 1.1091949753450539e-11 1.0640235764622199e-10 4.6041836514093303e-11 57154/5718/51176/6046/2309/5682/1499/2648/10018/1029/864/5707/3280/5717/463/5705/6097/64750/6696/7316/10213/865/9759/83439/1026/10413/5714/6714/6934/4609/4089/22938/8850/5701/1387/4088/2033/595/5702/7157/861/9794/6233/6932/7311/25937/7040/3845/3516/4851/3676/7314/4193 53 Human_SARS_coronavirus R-HSA-8854691 Interleukin-20 family signaling 22/2473 25/10654 1.1264681883423968e-11 1.0640235764622199e-10 4.6041836514093303e-11 6775/50616/11009/53833/6776/6774/3718/6772/3717/29949/163702/58985/3716/282618/53832/50604/3588/6777/55801/6773/7297/5781 22 Human_SARS_coronavirus R-HSA-1980143 Signaling by NOTCH1 44/2473 73/10654 1.1322699866143157e-11 1.0640235764622199e-10 4.6041836514093303e-11 8454/8841/79718/2648/9734/892/23462/51564/3280/6500/409/3091/10013/7316/9978/9611/8650/1272/9759/9612/1024/4609/5664/10014/22938/8850/1387/6907/26508/2033/408/55294/3066/3065/7088/83737/9794/6233/7311/388585/3516/4851/5663/7314 44 Human_SARS_coronavirus R-HSA-5654738 Signaling by FGFR2 44/2473 73/10654 1.1322699866143157e-11 1.0640235764622199e-10 4.6041836514093303e-11 5295/2963/5434/5440/4893/6464/5290/5335/5430/5436/5594/3178/5441/5438/5431/5435/4686/7316/673/5433/2263/6714/8569/2962/867/5437/4670/2247/5439/6654/6233/2885/7073/7311/5518/3845/3265/5781/5432/22916/7314/5595/5515/5516 44 Human_SARS_coronavirus R-HSA-8848021 Signaling by PTK6 36/2473 54/10654 1.2406299210052287e-11 1.1500974673102526e-10 4.97663780545483e-11 1017/1019/4893/1796/685/5770/207/9021/55620/27043/1027/3091/2064/5921/10657/10457/7316/1950/5753/6774/867/6421/2908/595/2066/6233/1398/7311/2034/387/1956/3845/3265/5829/7314/5879 36 Human_SARS_coronavirus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 36/2473 54/10654 1.2406299210052287e-11 1.1500974673102526e-10 4.97663780545483e-11 1017/1019/4893/1796/685/5770/207/9021/55620/27043/1027/3091/2064/5921/10657/10457/7316/1950/5753/6774/867/6421/2908/595/2066/6233/1398/7311/2034/387/1956/3845/3265/5829/7314/5879 36 Human_SARS_coronavirus R-HSA-8878166 Transcriptional regulation by RUNX2 62/2473 121/10654 1.5320204947720005e-11 1.4106926971994528e-10 6.104270992945308e-11 8454/57154/5718/7291/25/1019/8841/6662/5682/5707/23462/10273/207/5594/3280/5717/6500/4086/5925/10013/5705/1277/7316/10213/9978/891/865/4094/11059/9759/983/1026/10413/579/5714/6772/6714/2099/4089/2932/5701/6502/650/2908/10000/595/55294/5702/23314/861/208/6233/7525/25925/7311/25937/367/860/581/4091/7314/5595 62 Human_SARS_coronavirus R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 38/2473 59/10654 1.6328871636640487e-11 1.493547459031383e-10 6.462795510922972e-11 6203/6206/6194/1965/6191/6217/6222/8667/26986/6202/6232/6218/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/6207/6233/1975/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1968/6230 38 Human_SARS_coronavirus R-HSA-192823 Viral mRNA Translation 50/2473 89/10654 1.7851063858859486e-11 1.621964212871206e-10 7.018473347087314e-11 6158/6144/6203/9349/4736/6206/6194/6191/6128/6132/6147/6129/6217/6222/6152/6136/6125/6141/6202/6232/6134/6169/6175/6218/6193/6210/6231/6229/11224/6205/6130/6142/6204/6228/6124/6207/6233/7311/3921/6188/6189/6135/6201/6187/6208/6157/6137/6122/6133/6230 50 Human_SARS_coronavirus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 25/2473 31/10654 2.0775252849916942e-11 1.8752399282951346e-10 8.11443393861022e-11 3725/5601/9252/1849/5594/5528/4205/9261/5519/5598/1432/4208/5602/2002/1385/2353/6196/5518/1386/5599/5600/51231/5595/5515/5516 25 Human_SARS_coronavirus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 42/2473 69/10654 2.1148313482585042e-11 1.8964369998762535e-10 8.206156728020616e-11 3303/6118/4928/6782/5903/573/7531/5594/3308/10049/348995/79023/472/57122/23636/3313/10808/3305/9261/9532/23279/4927/79902/6119/2932/57805/23225/3309/7266/6767/9531/8086/22824/9972/23411/8021/6117/6396/3312/55746/8480/5595 42 Human_SARS_coronavirus R-HSA-2559585 Oncogene Induced Senescence 26/2473 33/10654 2.1573149052458145e-11 1.92197146103718e-10 8.316648028425424e-11 1019/2077/1029/7027/57690/5594/27327/5925/192670/7316/2114/6667/4194/192669/7157/23112/6233/1030/7311/3397/4343/26523/2113/7314/5595/4193 26 Human_SARS_coronavirus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 36/2473 55/10654 2.7914620337009662e-11 2.470894135637242e-10 1.0691915701238336e-10 1147/834/596/351/4790/6885/842/835/7295/330/23118/841/7316/5970/22861/7128/1432/329/598/10628/5603/10454/83737/3654/7189/6233/3326/7311/5600/1540/3551/6300/5608/4791/7314/257397 36 Human_SARS_coronavirus R-HSA-202733 Cell surface interactions at the vascular wall 67/2473 137/10654 3.546965439376501e-11 3.119510630015744e-10 1.3498572927181827e-10 5295/29802/5777/6693/3635/4893/6464/857/5290/5335/6385/960/2817/5680/5675/3684/7010/2993/4312/1277/6383/5196/338/50848/3688/2621/5670/6714/8797/914/4267/4067/682/2335/2534/3690/5624/83692/5678/5671/6654/2885/7525/440533/3685/3932/5676/6382/3543/5673/5296/7040/3687/3845/3265/5781/8795/1278/3689/5672/2207/10544/2147/5627/5669/3676/9046 67 Human_SARS_coronavirus R-HSA-380259 Loss of Nlp from mitotic centrosomes 42/2473 70/10654 4.107125166295977e-11 3.5664403342772663e-10 1.5432502290412602e-10 115106/55559/22981/7531/10142/203068/54801/7532/1454/10382/95681/121441/7277/79441/5116/5048/1781/23354/8655/9738/983/1639/5566/84131/7283/3320/22919/4751/5577/54930/5518/10383/54820/5347/9662/55142/23332/1453/9793/93323/55755/1778 42 Human_SARS_coronavirus R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 42/2473 70/10654 4.107125166295977e-11 3.5664403342772663e-10 1.5432502290412602e-10 115106/55559/22981/7531/10142/203068/54801/7532/1454/10382/95681/121441/7277/79441/5116/5048/1781/23354/8655/9738/983/1639/5566/84131/7283/3320/22919/4751/5577/54930/5518/10383/54820/5347/9662/55142/23332/1453/9793/93323/55755/1778 42 Human_SARS_coronavirus R-HSA-453279 Mitotic G1-G1/S phases 71/2473 149/10654 4.2883138290273936e-11 3.700356335487789e-10 1.6011976163995037e-10 8454/5718/1017/6118/25/894/1019/5682/1029/7027/5707/8317/207/5717/1027/6500/7153/5925/4173/5705/4149/286826/5934/7316/10213/891/5753/1875/993/890/983/1026/84515/5714/5933/5111/6714/4171/4609/5519/6119/5928/5701/10926/4067/3717/6502/10000/1874/595/81620/5702/3065/5520/8900/896/208/6233/28227/55957/1030/7311/5518/23649/6117/7465/1859/4176/7314/5515/5516 71 Human_SARS_coronavirus R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 30/2473 42/10654 4.426991076984501e-11 3.7833831221329195e-10 1.6371245058178355e-10 9070/51176/8945/6662/1487/1499/207/8085/83595/5929/6736/6657/7534/7316/83439/6934/9580/324/3065/7088/208/57680/6233/6932/7514/7311/331/25776/7314/4221 30 Human_SARS_coronavirus R-HSA-162909 Host Interactions of HIV factors 64/2473 129/10654 4.4396842759723034e-11 3.7833831221329195e-10 1.6371245058178355e-10 5718/5905/8945/1173/4928/3837/164/5903/8065/162/5682/3159/5707/1174/5717/4869/6500/348995/79023/57122/5705/23636/160/919/7316/10213/9978/293/292/567/3055/926/5714/23279/4927/79902/5701/23225/2534/5702/5902/5901/8086/3836/6233/7514/163/1025/7311/9972/3932/8021/8905/6396/904/55690/1104/5062/55746/8907/8480/940/7314/5879 64 Human_SARS_coronavirus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 37/2473 58/10654 4.597287137068241e-11 3.799685513287727e-10 1.6441787858633407e-10 8454/8841/79718/2648/9734/892/23462/51564/3280/6500/10013/7316/9978/9611/9759/9612/1024/4609/5664/10014/22938/8850/1387/6907/26508/2033/55294/3066/3065/9794/6233/7311/388585/3516/4851/5663/7314 37 Human_SARS_coronavirus R-HSA-2644603 Signaling by NOTCH1 in Cancer 37/2473 58/10654 4.597287137068241e-11 3.799685513287727e-10 1.6441787858633407e-10 8454/8841/79718/2648/9734/892/23462/51564/3280/6500/10013/7316/9978/9611/9759/9612/1024/4609/5664/10014/22938/8850/1387/6907/26508/2033/55294/3066/3065/9794/6233/7311/388585/3516/4851/5663/7314 37 Human_SARS_coronavirus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 37/2473 58/10654 4.597287137068241e-11 3.799685513287727e-10 1.6441787858633407e-10 8454/8841/79718/2648/9734/892/23462/51564/3280/6500/10013/7316/9978/9611/9759/9612/1024/4609/5664/10014/22938/8850/1387/6907/26508/2033/55294/3066/3065/9794/6233/7311/388585/3516/4851/5663/7314 37 Human_SARS_coronavirus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 37/2473 58/10654 4.597287137068241e-11 3.799685513287727e-10 1.6441787858633407e-10 8454/8841/79718/2648/9734/892/23462/51564/3280/6500/10013/7316/9978/9611/9759/9612/1024/4609/5664/10014/22938/8850/1387/6907/26508/2033/55294/3066/3065/9794/6233/7311/388585/3516/4851/5663/7314 37 Human_SARS_coronavirus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 37/2473 58/10654 4.597287137068241e-11 3.799685513287727e-10 1.6441787858633407e-10 8454/8841/79718/2648/9734/892/23462/51564/3280/6500/10013/7316/9978/9611/9759/9612/1024/4609/5664/10014/22938/8850/1387/6907/26508/2033/55294/3066/3065/9794/6233/7311/388585/3516/4851/5663/7314 37 Human_SARS_coronavirus R-HSA-5675221 Negative regulation of MAPK pathway 29/2473 40/10654 5.1860524880141453e-11 4.260637133865513e-10 1.8436392078411463e-10 4893/5604/5525/5526/8844/1849/5594/5528/7316/673/5605/5519/5529/5894/1847/6233/5527/7311/5518/5536/1843/3845/3265/369/7529/7314/5595/5515/5516 29 Human_SARS_coronavirus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 18/2473 19/10654 5.416273080283888e-11 4.371250980087938e-10 1.8915034162725157e-10 5295/4893/6464/5290/5335/7316/1950/867/3320/6654/6233/2885/7311/1956/3845/3265/11140/7314 18 Human_SARS_coronavirus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 18/2473 19/10654 5.416273080283888e-11 4.371250980087938e-10 1.8915034162725157e-10 5295/4893/6464/5290/5335/7316/1950/867/3320/6654/6233/2885/7311/1956/3845/3265/11140/7314 18 Human_SARS_coronavirus R-HSA-8851708 Signaling by FGFR2 IIIa TM 18/2473 19/10654 5.416273080283888e-11 4.371250980087938e-10 1.8915034162725157e-10 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2263/2962/5437/2247/5439/5432/22916 18 Human_SARS_coronavirus R-HSA-8854518 AURKA Activation by TPX2 43/2473 73/10654 5.6473798450794236e-11 4.531114121315187e-10 1.9606785057708805e-10 115106/55559/22981/7531/10142/203068/54801/7532/1454/10382/95681/121441/7277/79441/5116/5048/1781/23354/8655/9738/983/1639/6790/5566/84131/7283/3320/22919/4751/5577/54930/5518/10383/54820/5347/9662/55142/23332/1453/9793/93323/55755/1778 43 Human_SARS_coronavirus R-HSA-177929 Signaling by EGFR 33/2473 49/10654 5.905930478157372e-11 4.711009660483672e-10 2.0385219031093994e-10 5295/4893/6464/685/5290/5335/5782/8027/2060/7039/58513/7316/1950/6714/867/55824/9146/1445/998/6654/30011/6233/2885/7311/1956/29924/3845/3265/5781/10254/10252/5829/7314 33 Human_SARS_coronavirus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 27/2473 36/10654 6.61956887278056e-11 5.249739013557762e-10 2.2716378729834108e-10 4893/71/5604/8844/5594/409/7414/673/6714/5605/10256/2244/2335/3690/408/1445/5894/2266/8826/2243/7450/60/3845/3265/369/7529/5595 27 Human_SARS_coronavirus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 16/2473 16/10654 6.841618925929773e-11 5.394655842744625e-10 2.334345477449723e-10 57154/5590/50855/23370/50848/7316/7046/2280/6233/7048/7311/56288/387/7040/57530/7314 16 Human_SARS_coronavirus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 78/2473 171/10654 7.11882052295338e-11 5.58115528999545e-10 2.41504648117035e-10 10921/6158/5718/6144/6203/9349/4736/6206/6194/2107/6191/6128/5682/6132/6147/6129/6217/5707/89884/6222/6152/6136/6125/5717/6141/26986/23053/6202/5705/3670/6232/26019/2935/6134/6169/22794/4686/7316/10213/6175/9978/6218/65109/5714/6193/6210/6231/6229/11224/6205/6130/6142/6204/5701/6228/1605/6124/5702/8453/6207/6233/7311/3921/6188/6189/9775/6135/6201/6187/65110/22916/6208/6157/6137/6122/6133/7314/6230 78 Human_SARS_coronavirus R-HSA-8878171 Transcriptional regulation by RUNX1 100/2473 239/10654 7.959688589311146e-11 6.204939059394826e-10 2.684966725102564e-10 1912/5718/9070/27161/25/894/4773/2624/1437/11091/5579/6597/5682/6929/1459/5707/640/8535/8085/6045/9021/2625/57690/7122/5717/5929/27327/80012/1460/4005/6938/6598/5705/6599/192670/5196/100506658/7316/10213/865/28996/5079/10398/7082/1457/1911/10413/5714/23309/6714/2099/122809/8850/5701/1387/84733/3558/6604/8289/10138/2033/84333/6605/6602/57332/595/50943/8312/3458/192669/5702/3065/83737/861/896/5371/23112/57492/6233/9757/7311/6688/7161/860/58508/25942/4343/3276/3977/6601/3559/23466/26523/5781/7057/1493/7314/6015/55170/1514 100 Human_SARS_coronavirus R-HSA-5621481 C-type lectin receptors (CLRs) 68/2473 142/10654 8.371984228390602e-11 6.489470260650795e-10 2.808087484277312e-10 8454/1147/5718/5170/8945/4586/9252/4893/4773/4790/6885/5682/4772/7321/5707/5567/5336/3553/5532/9039/5568/4775/4582/5717/6500/23118/10892/3708/5705/841/5530/7316/10213/5970/4792/6850/3709/10768/8915/5714/6714/5566/5701/1387/4067/2534/2033/5534/10454/5702/5894/7189/6233/5580/7311/5971/3710/3845/3265/3551/5058/801/5062/997/2207/4791/7314/257397 68 Human_SARS_coronavirus R-HSA-9008059 Interleukin-37 signaling 19/2473 21/10654 1.0783234739824648e-10 8.311571945527762e-10 3.5965371929397407e-10 5778/834/5777/26469/5782/5783/27178/29110/25930/6774/5780/59307/8809/5775/4088/84867/5771/5784/5781 19 Human_SARS_coronavirus R-HSA-168325 Viral Messenger RNA Synthesis 30/2473 43/10654 1.139386160323554e-10 8.684654510910645e-10 3.757975405979442e-10 4928/2963/5434/5440/5903/5430/5436/348995/79023/57122/5441/23636/5438/5431/5435/5433/23279/4927/79902/2962/5437/23225/5439/8086/9972/8021/6396/5432/55746/8480 30 Human_SARS_coronavirus R-HSA-75893 TNF signaling 30/2473 43/10654 1.139386160323554e-10 8.684654510910645e-10 3.757975405979442e-10 7124/1147/81858/84888/7186/56957/6885/8737/55072/7375/330/23118/841/27005/7316/7128/7132/329/10454/55512/8567/6233/7311/8772/331/8717/1540/3551/7314/257397 30 Human_SARS_coronavirus R-HSA-8856828 Clathrin-mediated endocytosis 69/2473 146/10654 1.27989724716427e-10 9.70176255861535e-10 4.1980927444062133e-10 9318/1173/6857/685/7018/71/5868/10093/8027/1856/2060/7039/23208/1601/1785/29988/409/1080/29978/29763/112574/58513/160/950/338/7316/1950/10552/26130/3267/10094/55738/10980/22848/8301/7037/867/915/917/9146/4074/408/9322/10987/115548/185/5878/8976/30011/29979/6233/2885/7474/10096/10097/163/7311/3575/1213/1956/60/29924/3312/10109/6869/154/10254/7314/4952 69 Human_SARS_coronavirus R-HSA-1169408 ISG15 antiviral mechanism 42/2473 72/10654 1.4564812772636236e-10 1.0979628090141162e-9 4.751043611201179e-10 3839/4928/3837/3838/5903/5335/348995/9636/79023/57122/23636/11274/25820/1982/7706/9470/7316/4734/6772/23279/4927/79902/3840/23225/3661/8086/3836/51191/6233/3716/7311/9972/5610/5300/8021/9775/6396/55746/5495/8480/7314/5595 42 Human_SARS_coronavirus R-HSA-5675482 Regulation of necroptotic cell death 17/2473 18/10654 2.2240641292981034e-10 1.6674404291786874e-9 7.215255501433019e-10 7186/8737/356/355/330/841/7316/8797/329/8837/6233/7311/8772/331/8717/8795/7314 17 Human_SARS_coronavirus R-HSA-2871809 FCERI mediated Ca+2 mobilization 25/2473 33/10654 2.3777216207692236e-10 1.7729532954866168e-9 7.671824909118091e-10 6464/4773/2205/5335/4772/5336/5532/4775/3708/2206/5530/6850/3709/10768/27040/4067/5534/695/6654/2885/7410/7409/3710/801/2207 25 Human_SARS_coronavirus R-HSA-913531 Interferon Signaling 86/2473 199/10654 2.4038744886075237e-10 1.7737340588591946e-9 7.675203384966901e-10 3839/3665/818/5777/4928/815/3837/3838/5903/10379/5335/960/5770/7412/10410/2316/817/9021/85363/23650/348995/9636/79023/3383/57122/23636/11274/55223/25820/1982/7706/3662/9470/4684/7316/3663/3664/567/103/4734/6772/8651/23279/4927/3659/79902/3840/1958/7341/6059/3717/23225/5771/3458/3454/816/3661/8086/3836/5371/51191/6233/5580/3716/7311/9972/5610/5300/8021/9775/6396/7726/3456/6773/7297/4261/5781/55746/3105/3660/5495/5724/8480/7314/5595/8554 86 Human_SARS_coronavirus R-HSA-912526 Interleukin receptor SHC signaling 22/2473 27/10654 2.404624890290162e-10 1.7737340588591946e-9 7.675203384966901e-10 5295/5777/3635/6464/5290/1437/3561/1439/1438/3560/3718/8503/3558/3717/3636/6654/2885/3716/9846/5293/5296/3559 22 Human_SARS_coronavirus R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 15/2473 15/10654 2.961268663668311e-10 2.1160732325796474e-009 9.156554420553332e-10 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Human_SARS_coronavirus R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 15/2473 15/10654 2.961268663668311e-10 2.1160732325796474e-009 9.156554420553332e-10 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Human_SARS_coronavirus R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 15/2473 15/10654 2.961268663668311e-10 2.1160732325796474e-009 9.156554420553332e-10 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Human_SARS_coronavirus R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 15/2473 15/10654 2.961268663668311e-10 2.1160732325796474e-009 9.156554420553332e-10 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Human_SARS_coronavirus R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 15/2473 15/10654 2.961268663668311e-10 2.1160732325796474e-009 9.156554420553332e-10 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Human_SARS_coronavirus R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 15/2473 15/10654 2.961268663668311e-10 2.1160732325796474e-009 9.156554420553332e-10 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Human_SARS_coronavirus R-HSA-6802957 Oncogenic MAPK signaling 41/2473 71/10654 3.719878778208777e-10 2.644390509690385e-9 1.1442659563183806e-9 818/815/8805/22906/4893/71/5604/10018/10142/8844/817/5594/409/7414/673/8546/6714/5605/10256/3717/2244/2335/3690/408/1445/816/5894/2266/56829/8826/2243/7450/60/3845/3265/369/801/4763/5245/7529/5595 41 Human_SARS_coronavirus R-HSA-190236 Signaling by FGFR 47/2473 87/10654 4.3853289833251993e-10 3.1013769923310172e-9 1.3420106058575217e-9 5295/2963/5434/5440/4893/6464/5290/5335/5430/5436/5594/3178/5441/2260/5438/5431/5435/4686/7316/673/5433/2263/6714/8569/2962/2261/867/5437/4670/2247/5439/6654/6233/2885/7073/7311/5518/3845/3265/5781/5432/22916/7314/161742/5595/5515/5516 47 Human_SARS_coronavirus R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 56/2473 112/10654 4.95997318794149e-10 3.4897862635157563e-9 1.5100809058024295e-9 6158/6144/6203/9349/4736/6206/6194/6191/6128/10952/6132/6147/6129/6217/6222/6152/6136/6125/6141/6184/6202/6232/6134/6169/6731/6175/6218/6728/6193/6729/6210/6231/6229/11224/6205/6130/6142/6204/6228/6124/6207/6233/7311/6730/3921/6188/6189/6135/6201/6187/6208/6157/6137/6122/6133/6230 56 Human_SARS_coronavirus R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 27/2473 38/10654 5.13047939425393e-10 3.591335575977751e-9 1.554022759591416e-9 1912/6597/1459/8535/6045/80012/1460/6598/6599/865/28996/1457/1911/84733/6604/8289/10138/2033/84333/6605/6602/57332/861/57492/6601/23466/6015 27 Human_SARS_coronavirus R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 45/2473 82/10654 5.198051392206756e-10 3.6018820758119537e-9 1.558586382352265e-9 10844/115106/55559/22981/7531/10142/203068/54801/7532/1454/10382/95681/121441/7277/79441/5116/5048/1781/23354/728642/8655/9738/983/1639/5566/84131/7283/3320/22919/10426/4751/5577/54930/5518/10383/54820/5347/9662/55142/23332/1453/9793/93323/55755/1778 45 Human_SARS_coronavirus R-HSA-380287 Centrosome maturation 45/2473 82/10654 5.198051392206756e-10 3.6018820758119537e-9 1.558586382352265e-9 10844/115106/55559/22981/7531/10142/203068/54801/7532/1454/10382/95681/121441/7277/79441/5116/5048/1781/23354/728642/8655/9738/983/1639/5566/84131/7283/3320/22919/10426/4751/5577/54930/5518/10383/54820/5347/9662/55142/23332/1453/9793/93323/55755/1778 45 Human_SARS_coronavirus R-HSA-195721 Signaling by WNT 126/2473 331/10654 5.306131349472431e-10 3.658297593706621e-9 1.5829981915379273e-9 8454/57154/5718/9070/27161/51176/8945/1173/815/857/6662/22943/6885/1487/5579/6597/5682/1499/5525/59345/51701/864/1459/4772/139285/6423/5707/1856/5526/207/8085/1454/1452/5532/57690/83595/4041/5717/5929/50855/6500/27327/409/79577/6736/1460/9101/7471/3708/5705/6657/192670/160/7534/64750/8452/5530/5528/7316/10213/9978/23401/89780/1457/8658/83439/3709/5714/6934/4609/81847/5519/2932/5701/10524/1387/9580/1455/6422/324/2033/5534/2783/8312/5529/2782/192669/5702/3065/7088/8313/23112/208/23513/57680/6233/1855/5527/1488/7474/6932/1857/7514/4040/163/7311/5518/1213/387/3710/7855/331/8607/4343/5593/25776/3845/26523/801/7314/5879/4221/123169/5515/5592/5516 126 Human_SARS_coronavirus R-HSA-168638 NOD1/2 Signaling Pathway 26/2473 36/10654 6.064957735629709e-10 4.160561006641981e-9 1.800334822576398e-9 1147/834/6885/842/835/330/23118/841/7316/7128/1432/329/5603/10454/83737/3654/7189/6233/7311/5600/1540/3551/6300/5608/7314/257397 26 Human_SARS_coronavirus R-HSA-389357 CD28 dependent PI3K/Akt signaling 19/2473 22/10654 6.176419406856912e-10 4.19507298327113e-9 1.8152686531877533e-9 5295/5170/1326/5290/207/941/57761/64223/8503/10000/2534/942/208/79109/2475/3932/5296/940/253260 19 Human_SARS_coronavirus R-HSA-912631 Regulation of signaling by CBL 19/2473 22/10654 6.176419406856912e-10 4.19507298327113e-9 1.8152686531877533e-9 5295/5290/7316/3055/6850/8503/867/4067/29760/2534/6233/2885/7525/1398/7409/7311/5293/5296/7314 19 Human_SARS_coronavirus R-HSA-4615885 SUMOylation of DNA replication proteins 30/2473 45/10654 6.505724077217897e-10 4.396972134947269e-9 1.9026333313719963e-9 7150/5905/4928/5903/55143/9212/51588/3619/7153/348995/79023/6613/57122/23636/332/6790/5111/23279/4927/79902/7341/10401/23225/8086/7329/9972/8021/6396/55746/8480 30 Human_SARS_coronavirus R-HSA-6802952 Signaling by BRAF and RAF fusions 39/2473 67/10654 7.222464411508323e-10 4.857461359112461e-9 2.1018936677454565e-9 818/815/8805/22906/4893/71/5604/10018/10142/8844/817/5594/409/7414/673/8546/6714/5605/10256/3717/2244/2335/3690/408/1445/816/5894/2266/56829/8826/2243/7450/60/3845/3265/369/801/7529/5595 39 Human_SARS_coronavirus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 44/2473 80/10654 7.351136239226103e-10 4.919882400106445e-9 2.128904153490897e-9 3839/4928/3837/3838/5903/5335/2316/348995/9636/79023/57122/23636/11274/25820/1982/7706/9470/7316/4734/6772/23279/4927/79902/3840/6059/23225/3661/8086/3836/51191/6233/3716/7311/9972/5610/5300/8021/9775/6396/55746/5495/8480/7314/5595 44 Human_SARS_coronavirus R-HSA-201451 Signaling by BMP 22/2473 28/10654 8.75296697085088e-10 5.829645963110391e-9 2.5225719834235546e-9 4093/57154/9765/7321/6497/269/4086/658/64750/659/7323/93/4092/4089/92/650/94/657/2658/4091/268/4090 22 Human_SARS_coronavirus R-HSA-196299 Beta-catenin phosphorylation cascade 16/2473 17/10654 9.102478784193859e-10 6.004135044189411e-9 2.598075928282053e-9 1499/5525/139285/5526/1452/5528/23401/5519/2932/324/8312/5529/5527/5518/5515/5516 16 Human_SARS_coronavirus R-HSA-8934593 Regulation of RUNX1 Expression and Activity 16/2473 17/10654 9.102478784193859e-10 6.004135044189411e-9 2.598075928282053e-9 27161/894/57690/27327/192670/865/6714/595/192669/861/896/5371/23112/4343/26523/5781 16 Human_SARS_coronavirus R-HSA-5688426 Deubiquitination 115/2473 297/10654 9.457845101167198e-10 6.208690659713586e-9 2.686590096730446e-9 5718/10600/3607/23326/10617/221937/7186/56957/6885/5682/90865/2648/7321/5707/991/51377/8027/8737/8237/171023/7375/55611/2625/9817/4303/10445/91833/5717/57646/63967/409/6478/4086/1080/330/3091/9101/5705/11274/4287/55031/27005/7706/64750/7416/8239/7316/10213/993/79155/890/7417/80124/4792/9738/8658/983/11047/5714/4092/8678/2099/4609/7415/4194/4089/81847/27430/8850/7128/3416/29844/5701/9097/329/7046/6502/7347/4088/9146/324/2033/408/5728/8312/10454/8473/5702/7157/8900/9958/8313/4087/63891/84749/7189/6233/672/7048/7311/367/387/10318/60/23770/7040/8607/3054/1540/7874/154/10254/7314/4193/7528 115 Human_SARS_coronavirus R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 80/2473 185/10654 9.815201816349073e-10 6.412598520014728e-9 2.774823972140791e-9 84946/6158/6144/2091/6203/9349/55813/4736/6206/6194/22803/6191/6128/6132/6147/6129/6217/8780/6222/1454/81887/6152/6136/56902/84135/27043/6125/6141/51602/6202/51096/6232/90459/6134/6169/55781/6175/6218/6193/6210/6231/6229/11224/6205/6130/6142/28987/6204/6228/117246/10171/5822/10199/6124/6207/55759/705/6233/23160/7311/83732/3921/6188/6189/26354/6135/6201/79707/56915/1453/51202/6187/6208/6157/6137/10813/6122/6133/9188/6230 80 Human_SARS_coronavirus R-HSA-69242 S Phase 72/2473 161/10654 1.1361107078254633e-9 7.387411806334293e-9 3.1966397566154218e-9 8454/5718/1017/6118/1019/994/5682/7027/7321/5707/207/8697/5717/1027/6500/10274/5925/23244/4173/5705/10735/4149/286826/23047/8881/5934/5885/7316/10213/9978/5753/1875/993/890/1026/5425/84515/5714/5111/4171/4609/51433/6119/5928/2932/5701/6502/10000/1874/8243/9126/595/81620/5702/8900/29945/10393/208/6233/51434/55957/7311/113130/23649/6117/29882/10714/7465/5424/4176/7314/996 72 Human_SARS_coronavirus R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 14/2473 14/10654 1.2813297511765295e-9 8.101310684858058e-9 3.5055541094521596e-9 5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 14 Human_SARS_coronavirus R-HSA-4839744 truncated APC mutants destabilize the destruction complex 14/2473 14/10654 1.2813297511765295e-9 8.101310684858058e-9 3.5055541094521596e-9 5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 14 Human_SARS_coronavirus R-HSA-4839748 AMER1 mutants destabilize the destruction complex 14/2473 14/10654 1.2813297511765295e-9 8.101310684858058e-9 3.5055541094521596e-9 5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 14 Human_SARS_coronavirus R-HSA-5467337 APC truncation mutants have impaired AXIN binding 14/2473 14/10654 1.2813297511765295e-9 8.101310684858058e-9 3.5055541094521596e-9 5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 14 Human_SARS_coronavirus R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 14/2473 14/10654 1.2813297511765295e-9 8.101310684858058e-9 3.5055541094521596e-9 5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 14 Human_SARS_coronavirus R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 14/2473 14/10654 1.2813297511765295e-9 8.101310684858058e-9 3.5055541094521596e-9 5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 14 Human_SARS_coronavirus R-HSA-674695 RNA Polymerase II Pre-transcription Events 45/2473 84/10654 1.4756236285950482e-9 9.2445462028877e-9 4.000248625463144e-9 6884/85403/2963/5434/5440/6830/2959/5430/6874/5436/9646/79577/6749/5441/5438/5431/5435/4686/5433/6872/2960/9150/2962/54623/5437/8812/905/2068/5439/6873/1025/55677/6908/904/6883/51497/4300/2961/5432/22916/55840/80349/2957/123169/25920 45 Human_SARS_coronavirus R-HSA-72202 Transport of Mature Transcript to Cytoplasm 45/2473 84/10654 1.4756236285950482e-9 9.2445462028877e-9 4.000248625463144e-9 10921/7919/53981/4928/5903/6432/6431/8563/6430/29894/348995/79023/57122/23636/22794/81608/4686/8189/11338/29107/65109/23279/4927/79902/10898/10250/10569/23225/10189/9295/10482/51692/8086/9972/8021/9775/57187/6396/6427/2733/6426/55746/22916/8480/55339 45 Human_SARS_coronavirus R-HSA-5607764 CLEC7A (Dectin-1) signaling 51/2473 101/10654 1.889842985104686e-9 1.178574807074377e-8 5.099863366502599e-9 8454/1147/5718/5170/8945/4773/4790/6885/5682/4772/7321/5707/5336/3553/5532/9039/4775/5717/6500/23118/10892/3708/5705/841/5530/7316/10213/5970/4792/6850/3709/10768/8915/5714/6714/5701/5534/10454/5702/7189/6233/5580/7311/5971/3710/3551/801/997/4791/7314/257397 51 Human_SARS_coronavirus R-HSA-5357905 Regulation of TNFR1 signaling 24/2473 33/10654 2.2419853709251662e-9 1.3918569814069358e-8 6.022766130992112e-9 7124/1147/81858/84888/7186/56957/8737/55072/7375/330/841/27005/7316/7128/7132/329/8567/6233/7311/331/8717/1540/3551/7314 24 Human_SARS_coronavirus R-HSA-3928662 EPHB-mediated forward signaling 28/2473 42/10654 2.4401197869710686e-9 1.5080379944704083e-8 6.525498150079104e-9 71/2904/5747/1947/10093/5921/6383/2902/10552/10094/6714/4067/2534/9475/998/2048/8976/7525/10096/10097/6093/387/60/10095/3265/5058/10109/5879 28 Human_SARS_coronavirus R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 19/2473 23/10654 2.7744069610465016e-9 1.7069445518187445e-8 7.386195544159675e-9 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/9150/2962/5437/5439/51497/5432/22916/25920 19 Human_SARS_coronavirus R-HSA-186763 Downstream signal transduction 22/2473 29/10654 2.8289084610069485e-9 1.732706432366756e-8 7.497670921089846e-9 5295/4893/5290/5335/4690/5921/6778/6776/6774/6772/6714/5159/6654/2885/1398/5155/5296/3845/6777/3265/5781/5156 22 Human_SARS_coronavirus R-HSA-1643713 Signaling by EGFR in Cancer 20/2473 25/10654 2.9915066987470785e-9 1.816082827734952e-8 7.858452622698429e-9 5295/4893/6464/685/5290/5335/7039/7316/1950/867/3320/6654/6233/2885/7311/1956/3845/3265/11140/7314 20 Human_SARS_coronavirus R-HSA-9006115 Signaling by NTRK2 (TRKB) 20/2473 25/10654 2.9915066987470785e-9 1.816082827734952e-8 7.858452622698429e-9 5295/4908/627/4893/6464/5290/5335/4915/2904/6714/4909/2534/6654/2885/8851/3845/3265/1020/5781/5879 20 Human_SARS_coronavirus R-HSA-8868773 rRNA processing in the nucleus and cytosol 82/2473 195/10654 3.04462945025456e-9 1.8401901346913024e-8 7.962768420790967e-9 84946/6158/6144/2091/6203/55651/9349/55813/4736/6206/6194/22803/6191/6128/6132/6147/6129/6217/8780/6222/1454/81887/6152/6136/56902/84135/27043/6125/6141/51602/6202/51096/6232/90459/6134/6169/55781/6175/6218/6193/6210/6231/6229/11224/6205/6130/6142/28987/6204/1736/6228/117246/10171/5822/10199/6124/6207/55759/705/6233/23160/7311/83732/3921/6188/6189/26354/6135/6201/79707/56915/1453/51202/6187/6208/6157/6137/10813/6122/6133/9188/6230 82 Human_SARS_coronavirus R-HSA-5674135 MAP2K and MAPK activation 27/2473 40/10654 3.112198595134261e-9 1.8727791546158798e-8 8.103785815585058e-9 4893/71/5604/8844/5594/409/7414/673/6714/5605/10256/2244/2335/3690/408/1445/5894/2266/8826/2243/7450/60/3845/3265/369/7529/5595 27 Human_SARS_coronavirus R-HSA-4570464 SUMOylation of RNA binding proteins 30/2473 47/10654 3.132608965814734e-9 1.876829476461928e-8 8.121312143045322e-9 1912/4928/5903/8535/6045/80012/348995/51602/79023/6613/57122/23636/3183/3190/1911/23279/4927/79902/7341/84733/23225/57332/8086/7329/9972/8021/6396/55746/8480/6015 30 Human_SARS_coronavirus R-HSA-1295596 Spry regulation of FGF signaling 15/2473 16/10654 3.7117870229798313e-9 2.1950740497966933e-8 9.498402363705195e-9 5594/7316/673/6714/8569/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 15 Human_SARS_coronavirus R-HSA-193639 p75NTR signals via NF-kB 15/2473 16/10654 3.7117870229798313e-9 2.1950740497966933e-8 9.498402363705195e-9 4804/4790/5584/8878/4615/7316/5970/4792/4803/3654/7189/6233/7311/3551/7314 15 Human_SARS_coronavirus R-HSA-9614657 FOXO-mediated transcription of cell death genes 15/2473 16/10654 3.7117870229798313e-9 2.1950740497966933e-8 9.498402363705195e-9 2308/27113/2309/65018/10018/4802/356/4303/1649/4800/10370/1387/6794/2033/604 15 Human_SARS_coronavirus R-HSA-209560 NF-kB is activated and signals survival 13/2473 13/10654 5.542532472467237e-9 3.263671481641652e-8 1.4122377747781893e-8 4804/4790/8878/7316/5970/4792/4803/3654/7189/6233/7311/3551/7314 13 Human_SARS_coronavirus R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 44/2473 84/10654 5.654666778537314e-9 3.315471290663758e-8 1.4346523000877398e-8 7124/1052/1019/8841/4790/79718/5468/892/6721/51129/9862/1051/7471/3952/688/5465/9611/5469/1050/5970/9612/1024/9314/9968/1387/5346/10001/6604/6907/2033/9967/6256/896/10498/4023/9370/10499/23054/7040/51586/8202/8648/1959/96764 44 Human_SARS_coronavirus R-HSA-4791275 Signaling by WNT in cancer 24/2473 34/10654 5.942977068740655e-9 3.4696870375796505e-8 1.501383680523955e-8 22943/1487/1499/5525/139285/5526/1452/4041/5528/89780/8658/6934/5519/2932/324/8312/5529/5527/1488/4040/5518/7855/5515/5516 24 Human_SARS_coronavirus R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 16/2473 18/10654 6.412979602336023e-9 3.7124928330822886e-8 1.6064492541494633e-8 5295/8805/11052/26127/5290/613/9208/6776/6774/6772/399687/2885/9846/6777/7750/1523 16 Human_SARS_coronavirus R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 16/2473 18/10654 6.412979602336023e-9 3.7124928330822886e-8 1.6064492541494633e-8 7027/2810/5934/891/983/6790/5933/5111/1647/2033/995/1874/7157/10498/581/3276 16 Human_SARS_coronavirus R-HSA-6806834 Signaling by MET 42/2473 79/10654 7.012701133390262e-9 4.042615947483798e-8 1.7492982924511756e-8 5295/4893/6464/5290/85440/5770/5747/8027/10048/3911/2060/3082/9101/1277/1280/3912/3688/7316/6774/4233/3915/6714/1281/867/9146/2335/64759/5771/3913/6654/30011/6233/2885/1398/7311/3845/3265/5781/1278/10254/7314/5879 42 Human_SARS_coronavirus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 27/2473 41/10654 7.099792900210608e-9 4.0610383012625996e-8 1.7572699109345605e-8 53981/4928/5903/29894/348995/79023/57122/23636/81608/4686/8189/23279/4927/79902/10898/23225/10189/10482/51692/8086/9972/8021/6396/55746/22916/8480/55339 27 Human_SARS_coronavirus R-HSA-8941326 RUNX2 regulates bone development 23/2473 32/10654 7.1038570867567336e-9 4.0610383012625996e-8 1.7572699109345605e-8 25/8841/23462/5594/3280/4086/5925/10013/1277/865/4094/9759/10413/6714/4089/23314/7525/25925/25937/367/860/4091/5595 23 Human_SARS_coronavirus R-HSA-72312 rRNA processing 84/2473 205/10654 8.531050039764043e-9 4.845850577341964e-8 2.096869514823437e-8 60528/84946/6158/6144/2091/6203/55651/9349/55813/4736/6206/6194/22803/6191/6128/6132/6147/6129/6217/3028/8780/6222/1454/81887/6152/6136/56902/84135/27043/6125/6141/51602/6202/51096/6232/90459/6134/6169/55781/6175/6218/6193/6210/6231/6229/11224/6205/6130/6142/28987/6204/1736/6228/117246/10171/5822/10199/6124/6207/55759/705/6233/23160/7311/83732/3921/6188/6189/26354/6135/6201/79707/56915/1453/51202/6187/6208/6157/6137/10813/6122/6133/9188/6230 84 Human_SARS_coronavirus R-HSA-3232118 SUMOylation of transcription factors 17/2473 20/10654 8.617984991774337e-9 4.845850577341964e-8 2.096869514823437e-8 7020/6670/7021/1029/9112/51588/3090/6613/7341/10401/7157/668/7329/9063/4286/4193/8554 17 Human_SARS_coronavirus R-HSA-5213460 RIPK1-mediated regulated necrosis 17/2473 20/10654 8.617984991774337e-9 4.845850577341964e-8 2.096869514823437e-8 7186/8737/356/355/330/841/7316/8797/329/8837/6233/7311/8772/331/8717/8795/7314 17 Human_SARS_coronavirus R-HSA-5218859 Regulated Necrosis 17/2473 20/10654 8.617984991774337e-9 4.845850577341964e-8 2.096869514823437e-8 7186/8737/356/355/330/841/7316/8797/329/8837/6233/7311/8772/331/8717/8795/7314 17 Human_SARS_coronavirus R-HSA-112382 Formation of RNA Pol II elongation complex 35/2473 61/10654 9.105000752777433e-9 5.0734641098315484e-008 2.1953611768796945e-8 85403/2963/5434/5440/6830/5430/5436/9646/79577/6749/5441/5438/5431/5435/4686/5433/9150/2962/54623/5437/8812/905/2068/5439/1025/55677/904/51497/4300/5432/22916/55840/80349/123169/25920 35 Human_SARS_coronavirus R-HSA-75955 RNA Polymerase II Transcription Elongation 35/2473 61/10654 9.105000752777433e-9 5.0734641098315484e-008 2.1953611768796945e-8 85403/2963/5434/5440/6830/5430/5436/9646/79577/6749/5441/5438/5431/5435/4686/5433/9150/2962/54623/5437/8812/905/2068/5439/1025/55677/904/51497/4300/5432/22916/55840/80349/123169/25920 35 Human_SARS_coronavirus R-HSA-69206 G1/S Transition 60/2473 131/10654 9.133714541752133e-9 5.0734641098315484e-008 2.1953611768796945e-8 8454/5718/1017/6118/1019/5682/7027/5707/8317/207/5717/1027/6500/5925/4173/5705/4149/286826/5934/7316/10213/891/5753/1875/993/890/983/1026/84515/5714/5933/5111/4171/4609/5519/6119/5928/5701/10926/6502/10000/1874/595/81620/5702/3065/8900/208/6233/28227/55957/7311/5518/23649/6117/7465/4176/7314/5515/5516 60 Human_SARS_coronavirus R-HSA-180024 DARPP-32 events 20/2473 26/10654 1.0123594995834011e-8 5.600634005759783e-8 2.4234752027378535e-8 5575/84152/5567/5532/5568/5142/5573/5530/5528/5566/5519/5576/5534/5499/5577/5518/801/1020/5515/5516 20 Human_SARS_coronavirus R-HSA-203927 MicroRNA (miRNA) biogenesis 19/2473 24/10654 1.0405390953978103e-8 5.687727644963329e-8 2.4611618779801427e-8 27161/5434/5440/5430/5436/5441/192670/5438/5431/5435/5433/5437/57510/5439/192669/5901/29102/26523/5432 19 Human_SARS_coronavirus R-HSA-8940973 RUNX2 regulates osteoblast differentiation 19/2473 24/10654 1.0405390953978103e-8 5.687727644963329e-8 2.4611618779801427e-8 25/8841/23462/5594/3280/5925/10013/1277/865/4094/10413/6714/23314/7525/25925/25937/367/860/5595 19 Human_SARS_coronavirus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 19/2473 24/10654 1.0405390953978103e-8 5.687727644963329e-8 2.4611618779801427e-8 596/685/2309/5747/207/7039/5594/6722/1027/1950/10000/595/2002/208/7514/1385/2353/1956/5595 19 Human_SARS_coronavirus R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 47/2473 94/10654 1.2176427726979518e-8 6.629388429133293e-8 2.868632096080388e-8 10844/115106/55559/22981/7531/10142/203068/54801/7532/1454/10382/347688/95681/121441/7277/79441/10381/5116/5048/1781/23354/8655/9738/983/1639/5566/84131/7283/3320/22919/10376/10426/4751/5577/54930/5518/10383/54820/5347/9662/55142/23332/1453/9793/93323/55755/1778 47 Human_SARS_coronavirus R-HSA-111447 Activation of BAD and translocation to mitochondria 14/2473 15/10654 1.507417013851234e-8 8.078813058608958e-8 3.495819061727369e-8 596/7531/572/7532/207/10971/7533/2810/7534/10000/5534/208/637/7529 14 Human_SARS_coronavirus R-HSA-1170546 Prolactin receptor signaling 14/2473 15/10654 1.507417013851234e-8 8.078813058608958e-8 3.495819061727369e-8 8454/8945/2690/6500/6776/9978/1442/3717/5618/2688/5617/6777/2689/5781 14 Human_SARS_coronavirus R-HSA-5637810 Constitutive Signaling by EGFRvIII 14/2473 15/10654 1.507417013851234e-8 8.078813058608958e-8 3.495819061727369e-8 5295/4893/6464/5290/5335/1950/867/3320/6654/2885/1956/3845/3265/11140 14 Human_SARS_coronavirus R-HSA-5637812 Signaling by EGFRvIII in Cancer 14/2473 15/10654 1.507417013851234e-8 8.078813058608958e-8 3.495819061727369e-8 5295/4893/6464/5290/5335/1950/867/3320/6654/2885/1956/3845/3265/11140 14 Human_SARS_coronavirus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 27/2473 42/10654 1.5487204504041835e-8 8.267877268305601e-8 3.577629875191315e-8 53981/4928/5903/29894/348995/79023/57122/23636/81608/4686/8189/23279/4927/79902/10898/23225/10189/10482/51692/8086/9972/8021/6396/55746/22916/8480/55339 27 Human_SARS_coronavirus R-HSA-2682334 EPH-Ephrin signaling 46/2473 92/10654 1.7379768207923612e-8 9.242264333826045e-8 3.9992612277718964e-8 1173/71/2904/5747/1947/10093/4627/10627/4318/5921/6383/160/4313/2902/10398/10552/10094/6714/5664/4637/4067/2044/2534/9475/998/4628/2048/8976/7525/7410/10096/10097/6093/163/1213/103910/387/60/10095/3265/5058/10109/5062/5663/1969/5879 46 Human_SARS_coronavirus R-HSA-2980766 Nuclear Envelope Breakdown 31/2473 52/10654 1.843097397006753e-8 9.763434859819557e-8 4.224779239633444e-8 4928/5903/5579/91754/348995/79023/9133/57122/23636/7443/255919/891/983/23279/4927/79902/23225/9663/8086/2010/64900/23399/23592/23175/9972/5347/8021/6396/55746/7112/8480 31 Human_SARS_coronavirus R-HSA-8984722 Interleukin-35 Signalling 12/2473 12/10654 2.396734277610579e-8 1.2647382418775824e-7 5.472704990171525e-8 10148/3592/6775/3595/821/6774/6772/3717/9466/3716/7297/3572 12 Human_SARS_coronavirus R-HSA-432142 Platelet sensitization by LDL 15/2473 17/10654 2.472333060718304e-8 1.2946721218723333e-7 5.602233211109376e-8 5777/5321/5525/5526/2268/338/5528/5519/1432/5529/5527/5518/5781/5515/5516 15 Human_SARS_coronavirus R-HSA-9034015 Signaling by NTRK3 (TRKC) 15/2473 17/10654 2.472333060718304e-8 1.2946721218723333e-7 5.602233211109376e-8 5295/4908/4893/6464/5290/3667/5335/6714/6654/2885/581/3845/3265/4916/25920 15 Human_SARS_coronavirus R-HSA-9612973 Autophagy 55/2473 119/10654 2.5491636946092118e-8 1.3298298817505088e-7 5.754365914587135e-8 137492/51652/64422/7405/65018/1459/25978/1915/51160/27243/9140/8878/7249/1080/1460/10013/64419/5116/91782/7416/79720/9474/192111/7316/11152/8655/1457/51271/8678/6714/64223/8408/10226/5571/3320/55054/10542/6233/3326/2475/7311/23710/84557/5562/93343/11345/7251/7431/3312/11315/30849/57521/140735/92421/7314 55 Human_SARS_coronavirus R-HSA-5218920 VEGFR2 mediated vascular permeability 21/2473 29/10654 2.643697606860374e-8 1.373921635080467e-7 5.9451572977242867e-8 5170/857/1499/207/57761/1500/64223/10000/3320/4846/3728/208/79109/7410/2475/7409/5058/801/5062/5879/253260 21 Human_SARS_coronavirus R-HSA-111465 Apoptotic cleavage of cellular proteins 25/2473 38/10654 2.6666080734960772e-008 1.380598595032686e-7 5.974049467534409e-8 22985/2339/1499/5747/63967/118/841/100506658/7082/5339/660/8428/10134/329/999/836/324/4137/9414/5580/6709/6093/840/7431/6304 25 Human_SARS_coronavirus R-HSA-6807505 RNA polymerase II transcribes snRNA genes 39/2473 74/10654 3.315742355811586e-8 1.7102250045765023e-7 7.400390536912285e-8 6884/2963/5434/5440/55197/2959/5430/5436/5451/79871/5441/5438/5431/5435/4686/5433/2960/6667/2962/29101/51808/5437/8812/23248/905/64859/5439/80789/1025/7702/6908/51593/6619/904/2961/5432/22916/6618/2957 39 Human_SARS_coronavirus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 19/2473 25/10654 3.388269109554302e-8 1.734591499368844e-7 7.505827878195705e-8 9252/1849/5594/5528/4205/9261/5519/5598/1432/4208/2002/1385/6196/5518/5600/51231/5595/5515/5516 19 Human_SARS_coronavirus R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 19/2473 25/10654 3.388269109554302e-8 1.734591499368844e-7 7.505827878195705e-8 1017/994/2305/9133/891/993/890/983/5519/995/5520/8900/28227/7514/5518/5347/7465/5515/5516 19 Human_SARS_coronavirus R-HSA-5218921 VEGFR2 mediated cell proliferation 17/2473 21/10654 3.5401847386968136e-8 1.7989383190711215e-7 7.784265858187147e-8 5170/5590/4893/5335/5579/7422/3708/5921/3709/10768/6714/5580/3791/3710/3845/3265/801 17 Human_SARS_coronavirus R-HSA-5621575 CD209 (DC-SIGN) signaling 17/2473 21/10654 3.5401847386968136e-8 1.7989383190711215e-7 7.784265858187147e-8 9252/4893/4790/5567/5568/5970/5566/1387/4067/2534/2033/5894/5971/3845/3265/5058/5062 17 Human_SARS_coronavirus R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 34/2473 61/10654 4.019305964994272e-8 2.0348663409491295e-7 8.80516047487578e-8 26999/25/71/51517/5747/4690/4651/10093/4627/4771/5594/919/6850/10552/10094/4641/917/3320/998/695/8976/2885/1398/7410/10096/3326/10097/7409/60/10095/5058/10109/5879/5595 34 Human_SARS_coronavirus R-HSA-9020702 Interleukin-1 signaling 49/2473 103/10654 4.679361449956216e-8 2.3603249666690915e-7 1.0213466941854901e-7 8454/3557/1147/5718/8945/1326/351/4790/6885/5682/5604/4215/5707/3553/8878/54472/5717/6500/23118/5705/4615/7316/10213/9978/79155/5970/4792/4793/5714/3146/3552/5701/57162/10454/6288/5702/3654/7189/6233/7311/3551/7850/6416/5608/4791/3554/7314/257397/3556 49 Human_SARS_coronavirus R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 50/2473 106/10654 4.8319972212159085e-8 2.4283883470726105e-7 1.0507987016640725e-7 9318/1173/6857/685/7018/8027/1856/2060/7039/23208/1601/29988/409/1080/29978/58513/160/950/338/7316/1950/3267/10980/22848/8301/7037/867/915/917/9146/4074/408/10987/115548/185/30011/29979/6233/2885/7474/163/7311/3575/1213/1956/29924/6869/154/10254/7314 50 Human_SARS_coronavirus R-HSA-2408522 Selenoamino acid metabolism 54/2473 118/10654 5.17858271028646e-8 2.5930713425230014e-7 1.1220594116794329e-7 6158/6144/6203/9349/4736/6206/6194/6191/6128/6132/6147/6129/6217/4143/6222/6152/6136/6125/6141/6202/6232/6134/6169/1491/6175/6218/79048/6193/6210/6231/6229/11224/6205/6130/6142/6204/6228/6124/6207/6233/51091/7311/3921/6188/6189/6135/6201/6187/6208/6157/6137/6122/6133/6230 54 Human_SARS_coronavirus R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 39/2473 75/10654 5.371129027715276e-8 2.679705100372858e-7 1.1595470896196809e-7 5295/685/5290/3667/3815/7039/930/3082/941/2064/2260/2100/1950/2263/4233/6714/2099/8503/2261/5159/2247/2534/391/2066/942/2885/7409/8660/3932/5293/5155/1956/4254/118788/5296/5781/5156/940/5879 39 Human_SARS_coronavirus R-HSA-198323 AKT phosphorylates targets in the cytosol 13/2473 14/10654 6.093816784924621e-8 3.0183092523164553e-7 1.3060659953249047e-7 1147/842/572/207/84335/1027/7249/1026/2932/10000/208/2931/4193 13 Human_SARS_coronavirus R-HSA-8983432 Interleukin-15 signaling 13/2473 14/10654 6.093816784924621e-8 3.0183092523164553e-7 1.3060659953249047e-7 6464/3561/6776/3560/6774/3718/6654/2885/3716/9846/6777/3600/3601 13 Human_SARS_coronavirus R-HSA-5620912 Anchoring of the basal body to the plasma membrane 47/2473 98/10654 6.412642709816961e-8 3.164800646715421e-7 1.369454936893891e-7 115106/55559/22981/7531/54903/80776/10142/203068/54801/7532/1454/10382/95681/121441/7277/79441/5116/5048/1781/23354/8655/9738/79598/983/1639/5566/84131/7283/3320/22919/4751/5577/54930/5518/10383/54820/5347/9662/55142/23332/1453/9793/93323/51259/55755/9657/1778 47 Human_SARS_coronavirus R-HSA-447115 Interleukin-12 family signaling 32/2473 57/10654 7.999107898910984e-8 3.93361148290533e-7 1.7021304866952635e-7 10148/3592/6627/27250/3593/6775/3595/821/3313/6175/6774/6772/6647/149233/5898/6950/3717/9466/3458/998/6648/3716/3594/2939/302/51561/246778/7297/5062/3586/829/3572 32 Human_SARS_coronavirus R-HSA-350054 Notch-HLH transcription pathway 20/2473 28/10654 8.339641303803848e-8 4.0864242388638857e-7 1.7682547726862298e-7 8841/79718/2648/9734/51564/10013/9611/9759/9612/10014/22938/8850/1387/6907/4855/3066/3065/9794/3516/4851 20 Human_SARS_coronavirus R-HSA-75153 Apoptotic execution phase 30/2473 52/10654 8.844646691509061e-8 4.318453829448552e-7 1.8686573268443945e-7 3837/22985/2339/1499/5747/10059/63967/118/841/100506658/7082/5339/660/3146/8428/10134/329/999/836/324/4137/9414/3836/5580/6709/6093/840/7431/5062/6304 30 Human_SARS_coronavirus R-HSA-168253 Host Interactions with Influenza Factors 26/2473 42/10654 8.896103298251486e-8 4.328175079858524e-7 1.8728638522634708e-7 3839/4928/3837/3838/5903/348995/9636/79023/57122/23636/293/23279/4927/79902/10898/3840/23225/8086/3836/9972/5610/8021/7040/6396/55746/8480 26 Human_SARS_coronavirus R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 14/2473 16/10654 9.461085194723932e-8 4.5706369320990265e-7 1.9777805966732018e-7 5295/5170/6464/5290/2205/2206/6850/4067/2534/6654/2885/9846/5296/2207 14 Human_SARS_coronavirus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 14/2473 16/10654 9.461085194723932e-8 4.5706369320990265e-7 1.9777805966732018e-7 8454/1147/8945/1326/4790/5604/6500/7316/79155/6233/7311/3551/6416/7314 14 Human_SARS_coronavirus R-HSA-6803529 FGFR2 alternative splicing 19/2473 26/10654 9.837166622332473e-8 4.735646528364966e-7 2.0491826315772909e-7 2963/5434/5440/5430/5436/3178/5441/5438/5431/5435/4686/5433/2962/5437/4670/5439/7073/5432/22916 19 Human_SARS_coronavirus R-HSA-114604 GPVI-mediated activation cascade 23/2473 35/10654 1.0034918239182188e-7 4.813953784670616e-7 2.08306731207168e-7 5295/5170/5777/5590/5290/5336/1277/6850/8503/27040/4067/2534/391/998/7410/7409/3932/387/5296/5781/1278/2207/5879 23 Human_SARS_coronavirus R-HSA-195253 Degradation of beta-catenin by the destruction complex 41/2473 82/10654 1.0307985265098745e-7 4.918720774680069e-7 2.12840150139601e-7 8454/5718/51176/8945/1487/5682/1499/5525/139285/5707/5526/1452/5717/6500/5705/5528/7316/10213/9978/23401/83439/5714/6934/5519/2932/5701/324/8312/5529/5702/3065/7088/6233/5527/1488/6932/7311/5518/7314/5515/5516 41 Human_SARS_coronavirus R-HSA-1059683 Interleukin-6 signaling 11/2473 11/10654 1.0360862273196356e-7 4.918720774680069e-7 2.12840150139601e-7 9021/6774/6772/867/3717/3716/3570/7297/5781/3569/3572 11 Human_SARS_coronavirus R-HSA-9614399 Regulation of localization of FOXO transcription factors 11/2473 11/10654 1.0360862273196356e-7 4.918720774680069e-7 2.12840150139601e-7 2308/2309/7532/207/10971/4303/2810/7534/10000/208/7529 11 Human_SARS_coronavirus R-HSA-4551638 SUMOylation of chromatin organization proteins 37/2473 71/10654 1.0926006516810124e-7 5.169131358987411e-7 2.2367577769440694e-7 1912/4928/5903/83746/8535/6045/80012/348995/79023/6613/57122/23636/9759/1911/23279/4927/79902/7341/84733/23225/23512/57332/3066/3065/23314/1107/8086/7329/9972/9063/8021/6396/55746/6304/8480/6015/8554 37 Human_SARS_coronavirus R-HSA-1368082 RORA activates gene expression 15/2473 18/10654 1.1627508563141849e-7 5.482110566539732e-7 2.3721883992085383e-7 6095/1374/79718/5465/5469/1387/6604/6907/2033/6256/10498/10499/23054/8648/96764 15 Human_SARS_coronavirus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 34/2473 63/10654 1.1706997230720497e-7 5.50068500018785e-7 2.3802258248472827e-7 1147/3665/55718/5434/5440/4790/1499/8737/29110/5441/6778/4615/9208/5591/5435/7316/55703/5970/4792/4793/1387/5437/2033/1660/3661/6233/7311/661/3551/2547/11128/4791/7314/148022 34 Human_SARS_coronavirus R-HSA-5654741 Signaling by FGFR3 25/2473 40/10654 1.2042917993700244e-7 5.639209381350422e-7 2.4401673247519087e-7 5295/4893/6464/5290/5335/5594/7316/673/6714/8569/2261/867/2247/6654/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 25 Human_SARS_coronavirus R-HSA-198753 ERK/MAPK targets 17/2473 22/10654 1.2191072538782396e-7 5.689167184765119e-7 2.461784787638121e-7 9252/1849/5594/5528/4205/5519/5598/1432/4208/2002/6196/5518/5600/51231/5595/5515/5516 17 Human_SARS_coronavirus R-HSA-1181150 Signaling by NODAL 16/2473 20/10654 1.2453967514663433e-7 5.772582239904808e-7 2.497879686440319e-7 2309/55997/5045/6997/7044/130399/4838/91/93/4089/92/4088/4087/8928/10589/10637 16 Human_SARS_coronavirus R-HSA-8876384 Listeria monocytogenes entry into host cells 16/2473 20/10654 1.2453967514663433e-7 5.772582239904808e-7 2.497879686440319e-7 1499/8027/2060/7316/1500/4233/6714/867/999/9146/30011/6233/2885/7311/10254/7314 16 Human_SARS_coronavirus R-HSA-1236394 Signaling by ERBB4 32/2473 58/10654 1.3891076489167215e-7 6.417022539776908e-7 2.776738309371012e-7 5295/4893/6464/685/5290/5241/6678/23118/51741/6776/7316/1950/9611/11059/4734/10413/6714/2099/5664/2066/83737/3925/6654/6233/2885/7311/1956/3845/3265/5663/7314/6387 32 Human_SARS_coronavirus R-HSA-5655253 Signaling by FGFR2 in disease 26/2473 43/10654 1.7542119488410843e-7 8.076438905402577e-7 3.494791731354192e-7 5295/2963/5434/5440/4893/5290/5335/5430/5436/5441/5438/5431/5435/4686/5433/2263/2962/5437/2247/5439/6654/2885/3845/3265/5432/22916 26 Human_SARS_coronavirus R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 38/2473 75/10654 1.9307355601877674e-7 8.859428724339855e-7 3.833602731722939e-7 10921/7919/4928/5903/6432/6431/8563/6430/348995/79023/57122/23636/22794/4686/11338/29107/65109/23279/4927/79902/10250/10569/23225/10189/9295/10482/8086/9972/8021/9775/57187/6396/6427/2733/6426/55746/22916/8480 38 Human_SARS_coronavirus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 39/2473 78/10654 2.1025937422474472e-7 9.615862047878325e-7 4.160922353079159e-7 1147/3665/351/7186/4790/7321/8737/9140/29110/4214/9636/54476/841/7706/7323/9474/7316/5970/4792/4793/3146/7128/1387/2033/6288/83737/3661/7189/51191/6233/10010/7311/8772/5300/1540/3551/3456/4791/7314 39 Human_SARS_coronavirus R-HSA-177243 Interactions of Rev with host cellular proteins 23/2473 36/10654 2.1686035306352322e-7 9.884797488476872e-7 4.2772946014277707e-7 5905/4928/3837/5903/4869/348995/79023/57122/23636/23279/4927/79902/23225/5902/5901/8086/7514/9972/8021/6396/1104/55746/8480 23 Human_SARS_coronavirus R-HSA-209543 p75NTR recruits signalling complexes 12/2473 13/10654 2.450650664197685e-7 1.1060173392365869e-6 4.785896726480244e-7 4804/5584/8878/4615/7316/4803/3654/7189/6233/7311/3551/7314 12 Human_SARS_coronavirus R-HSA-5357786 TNFR1-induced proapoptotic signaling 12/2473 13/10654 2.450650664197685e-7 1.1060173392365869e-6 4.785896726480244e-7 7124/7186/56957/8737/7375/841/27005/7128/7132/8772/8717/1540 12 Human_SARS_coronavirus R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 12/2473 13/10654 2.450650664197685e-7 1.1060173392365869e-6 4.785896726480244e-7 7531/7532/10971/7533/2810/7534/891/983/995/1111/7465/7529 12 Human_SARS_coronavirus R-HSA-1538133 G0 and Early G1 19/2473 27/10654 2.595667987747991e-7 1.1676250751443423e-6 5.05248229539212e-7 1017/7027/7153/4149/286826/5934/1875/993/890/983/5933/5111/4609/5928/1874/3065/8900/55957/1859 19 Human_SARS_coronavirus R-HSA-187687 Signalling to ERKs 22/2473 34/10654 2.8784137307453384e-7 1.2905828884256876e-6 5.584538507534817e-7 4893/6464/5604/5594/673/9261/6714/5605/5898/1432/4914/4803/5603/6654/2885/1398/3845/5600/3265/6300/7529/5595 22 Human_SARS_coronavirus R-HSA-5696398 Nucleotide Excision Repair 50/2473 111/10654 2.9456536713318407e-7 1.3164289371554677e-6 5.696378092340676e-7 10450/9318/6118/5434/5440/5430/5436/10445/7515/6613/5441/7507/5438/5431/8450/5435/54778/7316/9978/5433/5425/5111/10980/6119/29844/7341/5437/10401/1642/2033/142/2068/5439/10987/7329/6233/7311/3980/60/8607/6117/10714/7874/5424/5432/91603/7314/8451/8554/7528 50 Human_SARS_coronavirus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 18/2473 25/10654 3.1308974471395e-7 1.3901589959467296e-6 6.015418702730976e-7 7321/991/8697/8881/7316/4085/51433/29945/10393/4751/6233/51434/701/7311/9184/29882/7314/996 18 Human_SARS_coronavirus R-HSA-9006335 Signaling by Erythropoietin 18/2473 25/10654 3.1308974471395e-7 1.3901589959467296e-6 6.015418702730976e-7 5295/4893/6464/5290/5335/5336/6776/4067/3717/6654/2885/2056/7409/8660/5293/3845/6777/3265 18 Human_SARS_coronavirus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 34/2473 65/10654 3.171868205170536e-7 1.4038074766109598e-6 6.074477649290941e-7 10450/6118/5434/5440/5430/5436/7515/5441/5438/5431/8450/5435/7316/9978/5433/5425/5111/6119/5437/1642/2033/2068/5439/6233/7311/3980/6117/10714/7874/5424/5432/91603/7314/8451 34 Human_SARS_coronavirus R-HSA-5689880 Ub-specific processing proteases 84/2473 220/10654 3.5297287765370035e-7 1.557166521353302e-6 6.738084379647555e-7 5718/10600/23326/7186/6885/5682/90865/2648/5707/991/8737/8237/7375/55611/2625/9817/4303/91833/5717/57646/63967/409/6478/4086/1080/330/3091/9101/5705/11274/55031/27005/64750/7416/8239/7316/10213/993/890/7417/4792/9738/8658/11047/5714/4092/8678/4609/4194/4089/81847/27430/3416/5701/9097/329/7046/6502/4088/9146/408/5728/8312/10454/5702/7157/8900/9958/8313/4087/63891/84749/7189/6233/7311/367/23770/8607/1540/7874/154/10254/7314/4193 84 Human_SARS_coronavirus R-HSA-111885 Opioid Signalling 43/2473 91/10654 3.897209263078265e-7 1.7137727913280064e-6 7.415742322456618e-7 818/815/3838/5321/5575/59345/84152/5567/2770/817/5532/5594/5568/5142/112/3708/5573/5530/5528/111/5443/3709/10768/5566/5519/4988/5576/5534/2783/2782/816/5613/5499/5577/5580/1385/5518/3710/801/1020/2773/5515/5516 43 Human_SARS_coronavirus R-HSA-445144 Signal transduction by L1 16/2473 21/10654 4.097807239775684e-7 1.790506857634471e-6 7.747781707118626e-7 5604/1459/5594/1460/2260/3688/4684/1457/5605/3690/7410/3685/1956/5058/5879/5595 16 Human_SARS_coronavirus R-HSA-6807004 Negative regulation of MET activity 16/2473 21/10654 4.097807239775684e-7 1.790506857634471e-6 7.747781707118626e-7 5770/8027/2060/3082/9101/7316/4233/867/9146/5771/30011/6233/2885/7311/10254/7314 16 Human_SARS_coronavirus R-HSA-3858494 Beta-catenin independent WNT signaling 61/2473 146/10654 4.1209197469708715e-007 1.7948894897917571e-6 7.766745989278436e-7 57154/5718/27161/51176/1173/815/6885/5579/5682/1499/59345/51701/4772/5707/1856/5532/57690/5717/50855/27327/409/7471/3708/5705/192670/160/64750/5530/7316/10213/83439/3709/5714/6934/5701/5534/2783/2782/192669/5702/23112/23513/6233/1855/7474/6932/1857/163/7311/1213/387/3710/7855/4343/5593/3845/26523/801/7314/5879/5592 61 Human_SARS_coronavirus R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 14/2473 17/10654 4.207526182008344e-7 1.8268120005428633e-6 7.904879302640593e-7 2308/857/2290/2309/2660/4303/1027/5934/1026/4089/1647/9314/4088/4087 14 Human_SARS_coronavirus R-HSA-110056 MAPK3 (ERK1) activation 10/2473 10/10654 4.47750783743005e-7 1.9137510133813176e-6 8.281076964454987e-7 5604/983/3717/3716/3570/7297/5781/3569/3572/5595 10 Human_SARS_coronavirus R-HSA-390450 Folding of actin by CCT/TriC 10/2473 10/10654 4.47750783743005e-7 1.9137510133813176e-6 8.281076964454987e-7 10694/10575/7203/10576/908/6950/10574/60/22948/10693 10 Human_SARS_coronavirus R-HSA-450341 Activation of the AP-1 family of transcription factors 10/2473 10/10654 4.47750783743005e-7 1.9137510133813176e-6 8.281076964454987e-7 3725/5601/5594/1432/5602/2353/1386/5599/5600/5595 10 Human_SARS_coronavirus R-HSA-74749 Signal attenuation 10/2473 10/10654 4.47750783743005e-7 1.9137510133813176e-6 8.281076964454987e-7 3643/6464/3667/5594/3630/6654/2885/8660/5595/2887 10 Human_SARS_coronavirus R-HSA-9020958 Interleukin-21 signaling 10/2473 10/10654 4.47750783743005e-7 1.9137510133813176e-6 8.281076964454987e-7 3561/6775/6776/50615/6774/3718/6772/3716/6777/59067 10 Human_SARS_coronavirus R-HSA-2424491 DAP12 signaling 20/2473 30/10654 4.922987550305053e-7 2.0911266003153352e-6 9.048606740661724e-7 5295/4893/6464/5290/5335/7305/5336/567/6850/27040/2534/695/6654/2885/7410/3932/5296/3845/3265/5879 20 Human_SARS_coronavirus R-HSA-4090294 SUMOylation of intracellular receptors 20/2473 30/10654 4.922987550305053e-7 2.0911266003153352e-6 9.048606740661724e-7 6095/5241/5468/51588/6613/2516/5465/4306/9759/2099/7341/10401/2908/6256/7329/367/9063/7421/10062/8554 20 Human_SARS_coronavirus R-HSA-72187 mRNA 3'-end processing 31/2473 58/10654 5.615822581281349e-7 2.3780582041722257e-6 1.029020122106134e-6 10921/7919/53981/6432/6431/8563/6430/79869/29894/22794/81608/4686/8189/11338/65109/1478/10898/10250/10569/10189/9295/51692/23283/10914/9775/57187/6427/6426/22916/1479/55339 31 Human_SARS_coronavirus R-HSA-9615710 Microautophagy 22/2473 35/10654 6.051358496145044e-7 2.5546042636033843e-6 1.105414151198641e-6 137492/51652/25978/51160/27243/1080/10013/5116/91782/79720/7316/51271/10226/6233/7311/93343/7251/7431/3312/11315/92421/7314 22 Human_SARS_coronavirus R-HSA-168276 NS1 Mediated Effects on Host Pathways 24/2473 40/10654 6.41539805398503e-7 2.6999773405114905e-6 1.1683191806417685e-6 3839/4928/3837/3838/5903/348995/9636/79023/57122/23636/23279/4927/79902/10898/3840/23225/8086/3836/9972/5610/8021/6396/55746/8480 24 Human_SARS_coronavirus R-HSA-201681 TCF dependent signaling in response to WNT 87/2473 233/10654 6.756007161653661e-7 2.8346305277641663e-6 1.2265855590447982e-6 5718/9070/51176/8945/857/6662/22943/1487/6597/5682/1499/5525/864/1459/139285/6423/5707/1856/5526/207/8085/1454/1452/83595/4041/5717/5929/79577/6736/1460/9101/7471/5705/6657/7534/64750/8452/5528/7316/10213/9978/23401/89780/1457/8658/83439/5714/6934/4609/81847/5519/2932/5701/10524/1387/9580/1455/6422/324/2033/8312/5529/5702/3065/7088/8313/208/57680/6233/1855/5527/7474/6932/1857/7514/4040/7311/5518/7855/331/8607/25776/7314/4221/123169/5515/5516 87 Human_SARS_coronavirus R-HSA-438064 Post NMDA receptor activation events 39/2473 81/10654 7.352971494782233e-7 3.075694174036958e-6 1.3308972795433825e-6 818/5170/815/3838/4893/2904/5575/2890/5567/817/10382/5594/347688/5568/7277/10381/5573/2902/6714/5566/5571/5576/2903/10376/4137/816/2066/5613/5577/88/1385/6196/5562/10383/3845/3265/801/5879/5595 39 Human_SARS_coronavirus R-HSA-2129379 Molecules associated with elastic fibres 23/2473 38/10654 8.846375031412684e-7 3.6557911274392174e-6 1.5819136073927566e-6 655/4052/3696/7042/7448/3688/4054/3693/2192/650/2335/3690/3694/2200/652/8425/3685/4236/8516/7040/2202/30008/7043 23 Human_SARS_coronavirus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 23/2473 38/10654 8.846375031412684e-7 3.6557911274392174e-6 1.5819136073927566e-6 4928/5903/51588/348995/79023/57122/23636/23279/4927/79902/7341/23225/8086/7329/5371/9972/9063/8021/6396/55746/8480/4193/8554 23 Human_SARS_coronavirus R-HSA-5655302 Signaling by FGFR1 in disease 23/2473 38/10654 8.846375031412684e-7 3.6557911274392174e-6 1.5819136073927566e-6 5295/8805/4893/11052/26127/5290/5335/613/2260/9208/6776/6774/6772/399687/2247/6654/2885/9846/3845/6777/3265/7750/1523 23 Human_SARS_coronavirus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 23/2473 38/10654 8.846375031412684e-7 3.6557911274392174e-6 1.5819136073927566e-6 7020/4435/7021/3815/7422/7039/4869/51741/2064/5308/1026/2099/4609/3329/10370/7341/1387/7913/2033/7329/1956/8089/7528 23 Human_SARS_coronavirus R-HSA-210990 PECAM1 interactions 11/2473 12/10654 9.796627022463997e-7 3.986714891328176e-6 1.725109098288393e-6 5777/3635/5335/6714/4067/2534/3690/7525/3685/3932/5781 11 Human_SARS_coronavirus R-HSA-389359 CD28 dependent Vav1 pathway 11/2473 12/10654 9.796627022463997e-7 3.986714891328176e-6 1.725109098288393e-6 941/2534/998/942/2885/7409/3932/5058/5062/940/5879 11 Human_SARS_coronavirus R-HSA-9020558 Interleukin-2 signaling 11/2473 12/10654 9.796627022463997e-7 3.986714891328176e-6 1.725109098288393e-6 6464/3561/6776/3560/6850/3718/3558/3716/3932/6777/3559 11 Human_SARS_coronavirus R-HSA-3371571 HSF1-dependent transactivation 17/2473 24/10654 9.821498784758919e-7 3.986714891328176e-6 1.725109098288393e-6 818/3303/815/817/84335/1410/3305/64223/26353/1387/3320/2033/816/3326/2475/3312/57521 17 Human_SARS_coronavirus R-HSA-452723 Transcriptional regulation of pluripotent stem cells 17/2473 24/10654 9.821498784758919e-7 3.986714891328176e-6 1.725109098288393e-6 63978/6997/79727/2516/6657/5460/6774/55211/57167/4089/9314/5087/79923/2247/4087/2034/84891 17 Human_SARS_coronavirus R-HSA-6783589 Interleukin-6 family signaling 17/2473 24/10654 9.821498784758919e-7 3.986714891328176e-6 1.725109098288393e-6 3589/9021/3976/6774/6772/867/3717/3716/1270/3570/5008/3977/7297/5781/3569/1489/3572 17 Human_SARS_coronavirus R-HSA-4086398 Ca2+ pathway 32/2473 62/10654 1.039396610304937e-6 4.206643508372784e-6 1.820275386467892e-6 27161/51176/815/6885/1499/59345/51701/4772/5532/57690/27327/3708/192670/5530/83439/3709/6934/5534/2783/2782/192669/23112/7474/6932/3710/7855/4343/5593/3845/26523/801/5592 32 Human_SARS_coronavirus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 38/2473 79/10654 1.0490370334170568e-6 4.23317297014177e-6 1.8317550676384525e-6 10450/9318/6118/5434/5440/5430/5436/7515/5441/7507/5438/5431/8450/5435/7316/9978/5433/5425/5111/10980/6119/5437/1642/2033/2068/5439/10987/6233/7311/3980/6117/10714/7874/5424/5432/91603/7314/8451 38 Human_SARS_coronavirus R-HSA-182971 EGFR downregulation 20/2473 31/10654 1.0844958998095943e-6 4.363426318295494e-6 1.8881175721333886e-6 685/5782/8027/2060/7039/58513/7316/1950/867/9146/998/30011/6233/2885/7311/1956/29924/10254/10252/7314 20 Human_SARS_coronavirus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 40/2473 85/10654 1.1244234452531136e-6 4.510844932418924e-6 1.9519077350654237e-6 8454/5718/1017/1019/994/5682/7027/5707/207/5717/1027/6500/5925/5705/4149/286826/5934/7316/10213/5753/1875/993/890/1026/5714/4609/5928/5701/6502/10000/1874/595/5702/8900/208/6233/55957/7311/7465/7314 40 Human_SARS_coronavirus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 29/2473 54/10654 1.1391998787104493e-6 4.556799514841797e-6 1.971792946425329e-6 10450/9318/5434/5440/5430/5436/5441/7507/5438/5431/8450/5435/7316/9978/5433/10980/5437/1642/2033/2068/5439/10987/6233/7311/7874/5432/91603/7314/8451 29 Human_SARS_coronavirus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 33/2473 65/10654 1.1505038556342768e-6 4.588637470727407e-6 1.9855696896503436e-6 3725/2963/5434/5440/4436/5430/5436/6749/472/5441/5438/5431/5435/5433/5395/9150/2962/9656/5437/8812/905/2068/5439/1111/7157/672/1025/2353/1386/904/51497/5432/25920 33 Human_SARS_coronavirus R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 16/2473 22/10654 1.1774340535502088e-6 4.668900351071926e-6 2.020300596903918e-6 3725/826/351/994/2309/10018/7531/356/823/2801/993/824/995/6648/8851/1020 16 Human_SARS_coronavirus R-HSA-8863678 Neurodegenerative Diseases 16/2473 22/10654 1.1774340535502088e-6 4.668900351071926e-6 2.020300596903918e-6 3725/826/351/994/2309/10018/7531/356/823/2801/993/824/995/6648/8851/1020 16 Human_SARS_coronavirus R-HSA-5654743 Signaling by FGFR4 24/2473 41/10654 1.2074784556020951e-6 4.774237582380619e-6 2.0658815378722333e-6 5295/4893/6464/5290/5335/5594/7316/673/6714/8569/867/2247/6654/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 24 Human_SARS_coronavirus R-HSA-167287 HIV elongation arrest and recovery 22/2473 36/10654 1.215283058480335e-6 4.7775597599857295e-6 2.067319092091416e-6 2963/5434/5440/5430/5436/6749/5441/5438/5431/5435/5433/9150/2962/5437/8812/905/5439/1025/904/51497/5432/25920 22 Human_SARS_coronavirus R-HSA-167290 Pausing and recovery of HIV elongation 22/2473 36/10654 1.215283058480335e-6 4.7775597599857295e-6 2.067319092091416e-6 2963/5434/5440/5430/5436/6749/5441/5438/5431/5435/5433/9150/2962/5437/8812/905/5439/1025/904/51497/5432/25920 22 Human_SARS_coronavirus R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 12/2473 14/10654 1.3498264578428991e-6 5.276244729801874e-6 2.2831072791224924e-6 5862/2801/5594/5861/9133/891/26003/983/8548/5347/64689/5595 12 Human_SARS_coronavirus R-HSA-877312 Regulation of IFNG signaling 12/2473 14/10654 1.3498264578428991e-6 5.276244729801874e-6 2.2831072791224924e-6 5777/5770/9021/6772/8651/7341/3717/5771/3458/3716/5781/8554 12 Human_SARS_coronavirus R-HSA-167044 Signalling to RAS 15/2473 20/10654 1.3585727562158493e-6 5.295346083886776e-6 2.291372710842521e-6 4893/6464/9261/6714/5898/1432/4914/4803/5603/6654/2885/3845/5600/3265/6300 15 Human_SARS_coronavirus R-HSA-8863795 Downregulation of ERBB2 signaling 19/2473 29/10654 1.4323493815920808e-6 5.567091647434377e-6 2.4089609399670008e-6 8065/685/26469/5782/10273/207/9101/2064/7316/1950/10000/3320/2066/208/6233/7311/1956/11140/7314 19 Human_SARS_coronavirus R-HSA-1433559 Regulation of KIT signaling 13/2473 16/10654 1.5049751240633993e-6 5.832841441285266e-6 2.5239547129698404e-6 5777/3815/9306/6714/8651/867/4067/2534/6654/2885/7525/3932/4254 13 Human_SARS_coronavirus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 39/2473 83/10654 1.6007314279472534e-6 6.169111008830426e-6 2.669463410296425e-6 8454/1147/5718/8945/4893/4773/4790/6885/5579/5966/5682/4772/5707/5532/4775/5717/6500/10892/5705/5530/7316/10213/5970/4792/4793/8915/5714/5701/5534/5702/2280/6233/7311/4794/3845/3265/3551/801/7314 39 Human_SARS_coronavirus R-HSA-69202 Cyclin E associated events during G1/S transition 39/2473 83/10654 1.6007314279472534e-6 6.169111008830426e-6 2.669463410296425e-6 8454/5718/1017/1019/5682/7027/5707/207/5717/1027/6500/5925/5705/4149/286826/5934/7316/10213/5753/1875/993/890/1026/5714/4609/5928/5701/6502/10000/1874/595/5702/8900/208/6233/55957/7311/7465/7314 39 Human_SARS_coronavirus R-HSA-72165 mRNA Splicing - Minor Pathway 28/2473 52/10654 1.622500840184027e-6 6.235493425020967e-6 2.6981880402883424e-6 23451/2963/5434/5440/55599/6432/6431/5430/4904/5436/23450/5441/5438/5431/5435/10594/4686/5433/9343/2962/5437/5439/9410/6634/6427/6426/5432/22916 28 Human_SARS_coronavirus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 40/2473 86/10654 1.6352174359880936e-6 6.249354657870932e-6 2.7041859958870692e-6 8454/5718/1017/8945/5682/7321/5707/991/8697/9212/5717/6500/5705/8881/7316/10213/891/890/4085/983/6790/5714/51433/5701/6502/5702/8900/29945/10393/4751/9232/6233/51434/701/7311/9184/5347/29882/7314/996 40 Human_SARS_coronavirus R-HSA-453276 Regulation of mitotic cell cycle 40/2473 86/10654 1.6352174359880936e-6 6.249354657870932e-6 2.7041859958870692e-6 8454/5718/1017/8945/5682/7321/5707/991/8697/9212/5717/6500/5705/8881/7316/10213/891/890/4085/983/6790/5714/51433/5701/6502/5702/8900/29945/10393/4751/9232/6233/51434/701/7311/9184/5347/29882/7314/996 40 Human_SARS_coronavirus R-HSA-5687128 MAPK6/MAPK4 signaling 41/2473 89/10654 1.6586460012722493e-6 6.316877872134243e-6 2.733404265677239e-6 5718/2308/27161/2118/3725/2309/5682/10642/5707/5567/57690/5568/5717/3315/27327/5705/192670/5596/7316/10213/983/5597/5714/4609/5566/5701/192669/5702/998/896/23112/6233/7514/7311/4343/26523/5058/8202/5062/7314/5879 41 Human_SARS_coronavirus R-HSA-165054 Rev-mediated nuclear export of HIV RNA 21/2473 34/10654 1.6620939590673918e-6 6.316877872134243e-6 2.733404265677239e-6 5905/4928/5903/348995/79023/57122/23636/23279/4927/79902/23225/5902/5901/8086/7514/9972/8021/6396/1104/55746/8480 21 Human_SARS_coronavirus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 42/2473 92/10654 1.6716562202977177e-6 6.335669431625604e-6 2.741535644803469e-6 6884/1017/6118/5883/1459/6874/9212/1460/6749/472/7316/6872/28996/890/1457/6790/641/4194/6119/1432/5571/10524/6794/1111/7157/8900/6873/6233/672/7311/5562/6908/8851/5300/6117/5600/6883/1020/26155/7314/4193/1263 42 Human_SARS_coronavirus R-HSA-6782135 Dual incision in TC-NER 33/2473 66/10654 1.7918014776165569e-6 6.7723185324791075e-6 2.9304800155886275e-6 10450/6118/5434/5440/5430/5436/5441/7507/5438/5431/8450/5435/7316/9978/5433/5425/5111/6119/5437/1642/2033/2068/5439/6233/7311/6117/10714/7874/5424/5432/91603/7314/8451 33 Human_SARS_coronavirus R-HSA-1368108 BMAL1:CLOCK,NPAS2 activates circadian gene expression 18/2473 27/10654 1.8694826664039725e-6 7.027206077551371e-6 3.0407735367032172e-6 79718/10135/28999/5465/406/5469/8553/1387/6604/6907/6256/10498/10499/23054/9575/8648/96764/5054 18 Human_SARS_coronavirus R-HSA-164952 The role of Nef in HIV-1 replication and disease pathogenesis 18/2473 27/10654 1.8694826664039725e-6 7.027206077551371e-6 3.0407735367032172e-6 1173/164/162/1174/160/919/567/3055/926/2534/163/3932/8905/55690/5062/8907/940/5879 18 Human_SARS_coronavirus R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 29/2473 55/10654 1.8781535493594264e-6 7.040510026560473e-6 3.0465303475372925e-6 3303/5241/1783/10382/347688/10294/830/7277/10381/1780/4306/1781/3305/8655/1639/832/2908/3320/10376/51143/3301/3326/367/10383/3312/55466/140735/829/1778 29 Human_SARS_coronavirus R-HSA-1489509 DAG and IP3 signaling 24/2473 42/10654 2.199099050630979e-6 8.221155033966494e-6 3.5574124897630068e-6 818/815/3838/5335/5575/5567/817/5568/112/3708/5573/111/3709/10768/5566/5576/816/5613/5577/5580/1385/3710/5581/801 24 Human_SARS_coronavirus R-HSA-3247509 Chromatin modifying enzymes 97/2473 274/10654 2.5702011844892166e-6 9.556411992192967e-6 4.135197455575292e-6 84678/54014/9070/10196/1810/1019/8841/23326/55250/11091/4790/9869/79718/79595/6597/2648/23186/8242/2146/5978/9112/9219/8085/6839/10445/5929/5931/284058/6598/6599/7403/55870/8819/9611/2874/10856/5970/11143/9612/29072/63976/1108/2122/9767/84444/8850/5928/10524/1387/55578/57459/3717/6604/6907/8289/54815/2033/23512/6605/6602/595/8473/3066/3065/1107/79084/23028/23135/10498/57492/9757/22992/57504/80854/58508/10499/1386/9575/51317/60/8607/8726/3054/6883/3276/6601/55729/10284/6187/51780/53615/8648/10362/4791/8089/55170/79723 97 Human_SARS_coronavirus R-HSA-4839726 Chromatin organization 97/2473 274/10654 2.5702011844892166e-6 9.556411992192967e-6 4.135197455575292e-6 84678/54014/9070/10196/1810/1019/8841/23326/55250/11091/4790/9869/79718/79595/6597/2648/23186/8242/2146/5978/9112/9219/8085/6839/10445/5929/5931/284058/6598/6599/7403/55870/8819/9611/2874/10856/5970/11143/9612/29072/63976/1108/2122/9767/84444/8850/5928/10524/1387/55578/57459/3717/6604/6907/8289/54815/2033/23512/6605/6602/595/8473/3066/3065/1107/79084/23028/23135/10498/57492/9757/22992/57504/80854/58508/10499/1386/9575/51317/60/8607/8726/3054/6883/3276/6601/55729/10284/6187/51780/53615/8648/10362/4791/8089/55170/79723 97 Human_SARS_coronavirus R-HSA-73856 RNA Polymerase II Transcription Termination 33/2473 67/10654 2.7497931540375924e-6 1.0196530290106963e-5 4.412185885852638e-6 10921/7919/53981/6432/6431/8563/6430/134353/79869/29894/22794/81608/4686/8189/11338/65109/1478/10898/10250/10569/10189/9295/51692/23283/6634/10914/9775/57187/6427/6426/22916/1479/55339 33 Human_SARS_coronavirus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 16/2473 23/10654 3.0325137499336454e-6 1.121457915069801e-5 4.852710327599876e-6 7321/991/8697/8881/7316/891/983/51433/29945/10393/6233/51434/7311/29882/7314/996 16 Human_SARS_coronavirus R-HSA-167172 Transcription of the HIV genome 35/2473 73/10654 3.048440384466958e-6 1.1241105678819133e-5 4.864188739338646e-6 6884/2963/5434/5440/2959/5430/6874/5436/6749/5441/5438/5431/5435/4686/5433/6872/2960/9150/2962/5437/8812/905/2068/5439/6873/1025/6908/904/6883/51497/2961/5432/22916/2957/25920 35 Human_SARS_coronavirus R-HSA-6804758 Regulation of TP53 Activity through Acetylation 19/2473 30/10654 3.056073191107534e-6 1.1241105678819133e-5 4.864188739338646e-6 3622/9219/207/5931/1108/5928/57459/10000/54815/2033/3066/3065/7157/1107/5371/208/5300/5608/53615 19 Human_SARS_coronavirus R-HSA-2559580 Oxidative Stress Induced Senescence 52/2473 125/10654 3.3711542391072485e-6 1.236690806431857e-5 5.351339687184037e-6 1912/3725/1019/5601/5606/9448/1029/7027/2146/8535/6045/57690/5594/27327/80012/5931/7295/192670/7316/9261/1911/4194/5928/1432/84733/5602/23512/57332/192669/7157/23135/23112/5609/6233/2353/1030/7311/4343/8726/5599/5600/23466/4217/26523/3456/6416/5608/7314/6015/5595/4193/23043 52 Human_SARS_coronavirus R-HSA-202403 TCR signaling 50/2473 119/10654 3.673816785448445e-6 1.3441271012360711e-5 5.8162320476994334e-6 5295/8454/1147/5718/5170/8945/55740/3635/5290/5335/4790/6885/5682/4690/7321/5707/5717/6500/23118/10892/5705/5788/919/7316/10213/5970/4792/8915/5714/5701/27040/915/917/55824/51466/7408/5728/1445/916/5702/7189/6233/7311/3932/5296/3551/5058/5062/997/7314 50 Human_SARS_coronavirus R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 15/2473 21/10654 3.730552836811571e-6 1.3612549181131583e-5 5.890346584439323e-6 7832/4849/4869/4850/10769/4848/23019/28984/995/7157/55571/5325/85456/29883/1263 15 Human_SARS_coronavirus R-HSA-2586552 Signaling by Leptin 10/2473 11/10654 3.8891723938534036e-6 1.3931970037511409e-5 6.028564601163446e-6 3667/3953/9021/3952/6776/6774/3717/8660/6777/5781 10 Human_SARS_coronavirus R-HSA-3371378 Regulation by c-FLIP 10/2473 11/10654 3.8891723938534036e-6 1.3931970037511409e-5 6.028564601163446e-6 7186/8737/356/355/841/8797/8837/8772/8717/8795 10 Human_SARS_coronavirus R-HSA-5218900 CASP8 activity is inhibited 10/2473 11/10654 3.8891723938534036e-6 1.3931970037511409e-5 6.028564601163446e-6 7186/8737/356/355/841/8797/8837/8772/8717/8795 10 Human_SARS_coronavirus R-HSA-69416 Dimerization of procaspase-8 10/2473 11/10654 3.8891723938534036e-6 1.3931970037511409e-5 6.028564601163446e-6 7186/8737/356/355/841/8797/8837/8772/8717/8795 10 Human_SARS_coronavirus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 10/2473 11/10654 3.8891723938534036e-6 1.3931970037511409e-5 6.028564601163446e-6 6885/23118/7316/10454/7189/6233/7311/7314/148022/257397 10 Human_SARS_coronavirus R-HSA-9020956 Interleukin-27 signaling 10/2473 11/10654 3.8891723938534036e-6 1.3931970037511409e-5 6.028564601163446e-6 10148/821/6774/6772/3717/9466/3716/246778/7297/3572 10 Human_SARS_coronavirus R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 10/2473 11/10654 3.8891723938534036e-6 1.3931970037511409e-5 6.028564601163446e-6 6885/23118/7316/80216/10454/7189/6233/7311/7314/257397 10 Human_SARS_coronavirus R-HSA-74751 Insulin receptor signalling cascade 28/2473 54/10654 4.342843604223356e-6 1.5516618294256365e-5 6.71426478284532e-6 5295/54106/5170/3643/4893/6464/5290/3667/5594/2322/57761/2260/2263/2261/2247/3630/208/6654/2885/8660/9846/5296/3845/3265/5781/30849/5595/2887 28 Human_SARS_coronavirus R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 14/2473 19/10654 4.435876885177385e-6 1.5766899187728942e-5 6.822564939296551e-6 7027/7153/4149/286826/5934/1875/993/5933/5111/4609/5928/1874/3065/55957 14 Human_SARS_coronavirus R-HSA-77595 Processing of Intronless Pre-mRNAs 14/2473 19/10654 4.435876885177385e-6 1.5766899187728942e-5 6.822564939296551e-6 53981/79869/29894/81608/4686/8189/1478/10898/51692/23283/10914/22916/1479/55339 14 Human_SARS_coronavirus R-HSA-113418 Formation of the Early Elongation Complex 20/2473 33/10654 4.488438621907426e-6 1.579009689553074e-5 6.832602922417783e-6 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/9150/2962/5437/2068/5439/51497/5432/22916/25920 20 Human_SARS_coronavirus R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 20/2473 33/10654 4.488438621907426e-6 1.579009689553074e-5 6.832602922417783e-6 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/9150/2962/5437/2068/5439/51497/5432/22916/25920 20 Human_SARS_coronavirus R-HSA-180746 Nuclear import of Rev protein 20/2473 33/10654 4.488438621907426e-6 1.579009689553074e-5 6.832602922417783e-6 4928/3837/5903/4869/348995/79023/57122/23636/23279/4927/79902/23225/5901/8086/9972/8021/6396/1104/55746/8480 20 Human_SARS_coronavirus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 20/2473 33/10654 4.488438621907426e-6 1.579009689553074e-5 6.832602922417783e-6 1147/351/4790/6885/23118/7316/5970/4792/4793/3146/10454/6288/3654/7189/6233/7311/3551/4791/7314/257397 20 Human_SARS_coronavirus R-HSA-1502540 Signaling by Activin 11/2473 13/10654 5.019949699292856e-6 1.7569823947524996e-5 7.602716515577795e-6 130399/91/93/3624/4089/92/4088/4087/3625/8928/10589 11 Human_SARS_coronavirus R-HSA-5607763 CLEC7A (Dectin-1) induces NFAT activation 11/2473 13/10654 5.019949699292856e-6 1.7569823947524996e-5 7.602716515577795e-6 4773/4772/5532/4775/3708/5530/3709/10768/5534/3710/801 11 Human_SARS_coronavirus R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 12/2473 15/10654 5.31291567733843e-6 1.8547888827756554e-5 8.025939311688428e-6 8027/2060/7316/4233/867/9146/30011/6233/2885/7311/10254/7314 12 Human_SARS_coronavirus R-HSA-8853659 RET signaling 23/2473 41/10654 5.503016976027233e-6 1.9162790078957777e-5 8.292015961740208e-6 5295/6464/1796/5290/5909/5335/5567/5568/6714/5566/8503/5598/5979/6654/2885/8660/9846/9260/5293/5296/5781/2887/9046 23 Human_SARS_coronavirus R-HSA-1852241 Organelle biogenesis and maintenance 102/2473 296/10654 5.656894006934494e-6 1.9648755892440823e-5 8.502300386172031e-6 6102/115106/10694/55763/79738/55559/8841/55735/79718/22981/7531/54903/80776/10142/203068/3842/54801/7532/10575/1454/10382/347688/95681/121441/7277/200186/79441/10013/10381/5116/3313/79989/5465/4209/7203/5048/1781/23354/10576/9611/5469/10989/8655/83658/9738/79598/983/1639/54205/89891/5566/64784/84131/1432/5571/4208/1387/6950/55212/6604/6907/7283/3320/8729/22919/10376/6648/6256/4751/10651/10498/5577/1385/54930/10499/23054/5518/10383/1386/54820/5347/22948/5600/3054/9662/55142/23332/1453/6300/801/9793/23373/8648/140735/93323/51259/55755/9657/96764/57576/1778/139322 102 Human_SARS_coronavirus R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 21/2473 36/10654 6.092678413919723e-6 2.1108976727014797e-5 9.134159025653173e-6 26999/25/71/51517/5747/4690/10093/5594/10552/10094/998/695/8976/2885/10096/10097/60/10095/10109/5879/5595 21 Human_SARS_coronavirus R-HSA-442755 Activation of NMDA receptors and postsynaptic events 41/2473 93/10654 6.550715712307199e-6 2.263874548434629e-5 9.79611205552502e-6 818/5170/815/3838/4893/2904/5575/2890/5567/817/10382/5594/347688/5568/7277/10381/5573/2902/6714/55327/5566/5571/5576/2903/10376/4137/816/2066/5613/5577/88/1385/6196/5562/10383/3845/3265/801/5879/57576/5595 41 Human_SARS_coronavirus R-HSA-5627123 RHO GTPases activate PAKs 16/2473 24/10654 7.133241492849168e-6 2.4589968161279043e-5 1.0640434281848536e-5 4659/4627/2316/4771/10627/10398/4637/998/4628/103910/5058/801/5062/4660/5500/5879 16 Human_SARS_coronavirus R-HSA-186797 Signaling by PDGF 29/2473 58/10654 7.513541550852141e-6 2.5836037613456486e-5 1.1179626526000813e-5 5295/4893/5290/5335/5340/4690/5782/5045/5921/1280/6778/6696/6776/6774/6772/6714/1281/5159/6654/2885/1398/5155/5296/3845/6777/3265/5781/7057/5156 29 Human_SARS_coronavirus R-HSA-76009 Platelet Aggregation (Plug Formation) 22/2473 39/10654 7.789127787896182e-6 2.6409868254530506e-5 1.1427931330025476e-5 5170/6464/5770/5747/207/1277/6850/6714/4352/2244/2335/3690/1445/6654/2885/1398/2266/2243/7450/1278/2147/7066 22 Human_SARS_coronavirus R-HSA-167161 HIV Transcription Initiation 25/2473 47/10654 7.815165095728415e-6 2.6409868254530506e-5 1.1427931330025476e-5 6884/2963/5434/5440/2959/5430/6874/5436/5441/5438/5431/5435/5433/6872/2960/2962/5437/2068/5439/6873/6908/6883/2961/5432/2957 25 Human_SARS_coronavirus R-HSA-167162 RNA Polymerase II HIV Promoter Escape 25/2473 47/10654 7.815165095728415e-6 2.6409868254530506e-5 1.1427931330025476e-5 6884/2963/5434/5440/2959/5430/6874/5436/5441/5438/5431/5435/5433/6872/2960/2962/5437/2068/5439/6873/6908/6883/2961/5432/2957 25 Human_SARS_coronavirus R-HSA-73776 RNA Polymerase II Promoter Escape 25/2473 47/10654 7.815165095728415e-6 2.6409868254530506e-5 1.1427931330025476e-5 6884/2963/5434/5440/2959/5430/6874/5436/5441/5438/5431/5435/5433/6872/2960/2962/5437/2068/5439/6873/6908/6883/2961/5432/2957 25 Human_SARS_coronavirus R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 25/2473 47/10654 7.815165095728415e-6 2.6409868254530506e-5 1.1427931330025476e-5 6884/2963/5434/5440/2959/5430/6874/5436/5441/5438/5431/5435/5433/6872/2960/2962/5437/2068/5439/6873/6908/6883/2961/5432/2957 25 Human_SARS_coronavirus R-HSA-75953 RNA Polymerase II Transcription Initiation 25/2473 47/10654 7.815165095728415e-6 2.6409868254530506e-5 1.1427931330025476e-5 6884/2963/5434/5440/2959/5430/6874/5436/5441/5438/5431/5435/5433/6872/2960/2962/5437/2068/5439/6873/6908/6883/2961/5432/2957 25 Human_SARS_coronavirus R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 25/2473 47/10654 7.815165095728415e-6 2.6409868254530506e-5 1.1427931330025476e-5 6884/2963/5434/5440/2959/5430/6874/5436/5441/5438/5431/5435/5433/6872/2960/2962/5437/2068/5439/6873/6908/6883/2961/5432/2957 25 Human_SARS_coronavirus R-HSA-159227 Transport of the SLBP independent Mature mRNA 20/2473 34/10654 8.52607385453604e-6 2.8531154459569384e-5 1.2345842500534858e-5 4928/5903/348995/79023/57122/23636/4686/23279/4927/79902/23225/10189/10482/8086/9972/8021/6396/55746/22916/8480 20 Human_SARS_coronavirus R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 20/2473 34/10654 8.52607385453604e-6 2.8531154459569384e-5 1.2345842500534858e-5 2963/5434/5440/5430/5436/6749/5441/5438/5431/5435/5433/9150/2962/5437/5439/1025/904/51497/5432/25920 20 Human_SARS_coronavirus R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 20/2473 34/10654 8.52607385453604e-6 2.8531154459569384e-5 1.2345842500534858e-5 2963/5434/5440/5430/5436/6749/5441/5438/5431/5435/5433/9150/2962/5437/5439/1025/904/51497/5432/25920 20 Human_SARS_coronavirus R-HSA-4085377 SUMOylation of SUMOylation proteins 20/2473 34/10654 8.52607385453604e-6 2.8531154459569384e-5 1.2345842500534858e-5 4928/5903/51588/348995/79023/6613/57122/23636/23279/4927/79902/7341/23225/8086/7329/9972/8021/6396/55746/8480 20 Human_SARS_coronavirus R-HSA-5654736 Signaling by FGFR1 26/2473 50/10654 8.892990842120953e-6 2.9686577701678704e-5 1.2845810820735607e-5 5295/4893/6464/5290/5335/5594/2260/7316/673/6714/8569/867/2247/6654/6233/2885/7311/5518/3845/3265/5781/7314/161742/5595/5515/5516 26 Human_SARS_coronavirus R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 49/2473 119/10654 8.981884273099982e-6 2.991054665702227e-5 1.2942725421636154e-5 6095/6822/8841/1374/79718/5468/892/4802/6721/51129/51/9862/57761/5465/406/335/9611/5469/2874/4800/9612/1024/6667/23309/336/9968/1387/10001/6604/6907/2033/9967/4199/6256/2168/10498/183/2274/10499/23054/9575/25942/196/405/51586/8202/8648/10062/96764 49 Human_SARS_coronavirus R-HSA-1566948 Elastic fibre formation 24/2473 45/10654 1.1167760192702392e-5 3.7099677928299474e-5 1.6053566327728172e-5 655/4052/3696/7042/5045/7448/3688/4054/3693/2192/650/2335/3690/3694/2200/652/8425/3685/4236/8516/7040/2202/30008/7043 24 Human_SARS_coronavirus R-HSA-3000170 Syndecan interactions 17/2473 27/10654 1.151167258760839e-5 3.796638170720844e-5 1.642860156733586e-5 6385/1277/6383/7448/3688/3693/1281/2247/2335/3690/87/3685/6382/7040/7057/1278/3691 17 Human_SARS_coronavirus R-HSA-354192 Integrin alphaIIb beta3 signaling 17/2473 27/10654 1.151167258760839e-5 3.796638170720844e-5 1.642860156733586e-5 5170/6464/5770/5747/207/6850/6714/2244/2335/3690/1445/6654/2885/1398/2266/2243/7450 17 Human_SARS_coronavirus R-HSA-9006921 Integrin signaling 17/2473 27/10654 1.151167258760839e-5 3.796638170720844e-5 1.642860156733586e-5 5170/6464/5770/5747/207/6850/6714/2244/2335/3690/1445/6654/2885/1398/2266/2243/7450 17 Human_SARS_coronavirus R-HSA-2028269 Signaling by Hippo 14/2473 20/10654 1.1616253186087649e-5 3.803699133964738e-5 1.645915537483591e-5 23286/7531/1856/7082/10413/6789/26524/836/9414/51421/9113/25937/6788/7529 14 Human_SARS_coronavirus R-HSA-5627117 RHO GTPases Activate ROCKs 14/2473 20/10654 1.1616253186087649e-5 3.803699133964738e-5 1.645915537483591e-5 4659/4627/389/10627/10398/4637/9475/4628/6093/103910/387/5058/4660/5500 14 Human_SARS_coronavirus R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 14/2473 20/10654 1.1616253186087649e-5 3.803699133964738e-5 1.645915537483591e-5 2648/23462/3280/22938/8850/1387/4088/59/2033/4855/9794/388585/3516/4851 14 Human_SARS_coronavirus R-HSA-1632852 Macroautophagy 41/2473 95/10654 1.2374363250864972e-5 4.0422919952825574e-5 1.7491581136561015e-5 51652/64422/7405/65018/1459/25978/27243/9140/8878/7249/1460/64419/91782/7416/9474/192111/7316/11152/8655/1457/8678/6714/64223/8408/10226/5571/55054/10542/6233/2475/7311/23710/84557/5562/11345/3312/30849/57521/140735/92421/7314 41 Human_SARS_coronavirus R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 25/2473 48/10654 1.2732793252641202e-5 4.1494993687942354e-5 1.7955482921589294e-5 2963/5434/5440/5430/5436/6749/5441/5438/5431/5435/4686/5433/9150/2962/5437/8812/905/2068/5439/1025/904/51497/5432/22916/25920 25 Human_SARS_coronavirus R-HSA-111471 Apoptotic factor-mediated response 13/2473 18/10654 1.4238611411516363e-5 4.6292357480095855e-5 2.0031371504353276e-5 1029/842/5594/54205/56616/836/840/331/581/57099/317/578/5595 13 Human_SARS_coronavirus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 9/2473 10/10654 1.5314021732612803e-5 4.955386277628483e-5 2.1442671939408197e-5 6885/23118/7316/10454/7189/6233/7311/7314/257397 9 Human_SARS_coronavirus R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 9/2473 10/10654 1.5314021732612803e-5 4.955386277628483e-5 2.1442671939408197e-5 2308/2309/4303/7295/8850/1387/10628/2033/23411 9 Human_SARS_coronavirus R-HSA-2029485 Role of phospholipids in phagocytosis 16/2473 25/10654 1.5540954968634268e-5 5.000933840326762e-5 2.1639762819888708e-5 5295/5290/23646/5335/5336/3708/919/6850/3709/10768/917/5580/3710/5296/5581/5338 16 Human_SARS_coronavirus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 20/2473 35/10654 1.5564130829588393e-5 5.000933840326762e-5 2.1639762819888708e-5 4928/5903/348995/79023/57122/23636/4686/23279/4927/79902/23225/10189/10482/8086/9972/8021/6396/55746/22916/8480 20 Human_SARS_coronavirus R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 20/2473 35/10654 1.5564130829588393e-5 5.000933840326762e-5 2.1639762819888708e-5 4928/5903/91754/348995/79023/9133/57122/23636/891/983/23279/4927/79902/23225/8086/9972/8021/6396/55746/8480 20 Human_SARS_coronavirus R-HSA-156711 Polo-like kinase mediated events 12/2473 16/10654 1.6736737337163484e-5 5.340186889904256e-5 2.3107759750698176e-5 2305/1063/9133/286826/891/993/5928/2033/995/55957/5347/7465 12 Human_SARS_coronavirus R-HSA-175474 Assembly Of The HIV Virion 12/2473 16/10654 1.6736737337163484e-5 5.340186889904256e-5 2.3107759750698176e-5 137492/51160/5045/79720/7316/9397/51271/6233/7311/93343/7251/7314 12 Human_SARS_coronavirus R-HSA-205043 NRIF signals cell death from the nucleus 12/2473 16/10654 1.6736737337163484e-5 5.340186889904256e-5 2.3107759750698176e-5 4804/8878/23421/7316/5664/4803/7189/6233/7311/5599/5663/7314 12 Human_SARS_coronavirus R-HSA-174490 Membrane binding and targetting of GAG proteins 11/2473 14/10654 1.8477068251276005e-5 5.854627630658356e-5 2.533381911685832e-5 137492/51160/79720/7316/9397/51271/6233/7311/93343/7251/7314 11 Human_SARS_coronavirus R-HSA-174495 Synthesis And Processing Of GAG, GAGPOL Polyproteins 11/2473 14/10654 1.8477068251276005e-5 5.854627630658356e-5 2.533381911685832e-5 137492/51160/79720/7316/9397/51271/6233/7311/93343/7251/7314 11 Human_SARS_coronavirus R-HSA-9027284 Erythropoietin activates RAS 11/2473 14/10654 1.8477068251276005e-5 5.854627630658356e-5 2.533381911685832e-5 4893/6464/4067/3717/6654/2885/2056/7409/8660/3845/3265 11 Human_SARS_coronavirus R-HSA-5689896 Ovarian tumor domain proteases 21/2473 38/10654 1.9256594536396246e-5 6.087568595376878e-5 2.6341788305911922e-5 56957/7321/8737/55611/7706/7316/79155/80124/983/2099/7415/7128/324/5728/7157/7189/6233/7311/387/10318/7314 21 Human_SARS_coronavirus R-HSA-9012852 Signaling by NOTCH3 25/2473 49/10654 2.029794703429201e-5 6.402019156562904e-5 2.7702461288180752e-5 23286/2648/23462/4904/3280/7316/1950/6772/5664/11060/22938/8850/5087/1387/26508/2033/9794/6233/7311/1956/388585/3516/4851/5663/7314 25 Human_SARS_coronavirus R-HSA-112409 RAF-independent MAPK1/3 activation 15/2473 23/10654 2.0768411485871264e-5 6.520425757120224e-5 2.8214823745709727e-5 5604/1849/5594/983/5605/3717/1847/3716/1843/3570/7297/5781/3569/3572/5595 15 Human_SARS_coronavirus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 15/2473 23/10654 2.0768411485871264e-5 6.520425757120224e-5 2.8214823745709727e-5 5601/6885/23118/7316/5602/10454/3654/7189/5609/6233/7311/5599/6416/7314/257397 15 Human_SARS_coronavirus R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 19/2473 33/10654 2.1963468697599693e-5 6.879881062353146e-5 2.9770238753776086e-5 3303/4928/5903/348995/79023/57122/23636/23279/4927/79902/23225/5901/8086/7514/9972/8021/6396/55746/8480 19 Human_SARS_coronavirus R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF) 27/2473 55/10654 2.363573663263497e-5 7.38684069703307e-5 3.196392629374445e-5 3837/79718/4802/6721/10484/10802/5465/5469/2194/4800/6667/1387/6604/6907/9632/5901/6256/4047/10498/9871/10499/23054/2224/31/8648/10427/96764 27 Human_SARS_coronavirus R-HSA-1266695 Interleukin-7 signaling 20/2473 36/10654 2.7403446349174403e-5 8.522145445115224e-5 3.687655386715503e-5 5295/54014/3667/6597/64109/3561/3082/6776/6774/3718/8651/8503/3716/85480/8660/1154/3575/5296/8835/6777 20 Human_SARS_coronavirus R-HSA-176033 Interactions of Vpr with host cellular proteins 20/2473 36/10654 2.7403446349174403e-5 8.522145445115224e-5 3.687655386715503e-5 4928/5903/3159/348995/79023/57122/23636/293/292/23279/4927/79902/23225/8086/3836/9972/8021/6396/55746/8480 20 Human_SARS_coronavirus R-HSA-157118 Signaling by NOTCH 82/2473 235/10654 2.745472512201843e-5 8.522145445115224e-5 3.687655386715503e-5 8454/5718/23286/27161/3725/8841/2208/79718/5682/5584/2648/9734/892/7027/5707/23462/207/51564/4904/5045/57690/3280/5717/6500/27327/409/3091/10013/5705/192670/7534/7316/10213/9978/1950/9611/8650/1272/9759/9612/1024/5714/6772/4609/5664/11060/10014/22938/8850/5087/5701/1387/4088/6907/59/26508/2033/408/4855/595/55294/192669/5702/3066/3065/7157/7088/83737/861/23112/9794/6233/1385/7311/1956/4343/388585/26523/3516/4851/5663/7314 82 Human_SARS_coronavirus R-HSA-1989781 PPARA activates gene expression 47/2473 117/10654 2.9207343785855303e-5 9.045705569795367e-5 3.914207412432551e-5 6095/6822/8841/1374/79718/5468/892/4802/6721/51129/51/9862/57761/5465/406/335/9611/5469/2874/4800/9612/1024/6667/336/9968/1387/10001/6604/6907/2033/9967/4199/6256/2168/10498/183/2274/10499/23054/9575/196/405/51586/8202/8648/10062/96764 47 Human_SARS_coronavirus R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 18/2473 31/10654 3.0947503207120626e-5 9.520173632325e-5 4.119516594008977e-5 4928/3837/5903/348995/79023/57122/23636/23279/4927/79902/23225/8086/3836/9972/8021/6396/55746/8480 18 Human_SARS_coronavirus R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 18/2473 31/10654 3.0947503207120626e-5 9.520173632325e-5 4.119516594008977e-5 4928/5903/348995/79023/57122/23636/23279/4927/79902/23225/5901/8086/7514/9972/8021/6396/55746/8480 18 Human_SARS_coronavirus R-HSA-1839124 FGFR1 mutant receptor activation 18/2473 31/10654 3.0947503207120626e-5 9.520173632325e-5 4.119516594008977e-5 5295/8805/11052/26127/5290/613/2260/9208/6776/6774/6772/399687/2247/2885/9846/6777/7750/1523 18 Human_SARS_coronavirus R-HSA-877300 Interferon gamma signaling 39/2473 92/10654 3.2871519117842866e-5 1.0089423765029175e-4 4.36583934592332e-5 3665/818/5777/815/10379/960/5770/7412/817/9021/85363/23650/3383/55223/7706/3662/4684/3663/3664/567/6772/8651/3659/7341/3717/5771/3458/816/3661/5371/5580/3716/7726/4261/5781/3105/3660/5724/8554 39 Human_SARS_coronavirus R-HSA-191859 snRNP Assembly 26/2473 53/10654 3.3874375476185986e-5 1.0327920700739371e-4 4.469040413700327e-5 4928/6606/5903/8487/348995/79023/57122/23636/10073/4686/23279/4927/79902/51808/23225/1207/79084/8086/9972/6634/8021/6396/55746/22916/8480/96764 26 Human_SARS_coronavirus R-HSA-194441 Metabolism of non-coding RNA 26/2473 53/10654 3.3874375476185986e-5 1.0327920700739371e-4 4.469040413700327e-5 4928/6606/5903/8487/348995/79023/57122/23636/10073/4686/23279/4927/79902/51808/23225/1207/79084/8086/9972/6634/8021/6396/55746/22916/8480/96764 26 Human_SARS_coronavirus R-HSA-2428924 IGF1R signaling cascade 26/2473 53/10654 3.3874375476185986e-5 1.0327920700739371e-4 4.469040413700327e-5 5295/54106/5170/4893/6464/5290/3667/2322/57761/2260/2263/2261/2247/3481/208/6654/2885/8660/9846/3479/5296/3845/3265/5781/30849/3480 26 Human_SARS_coronavirus R-HSA-199977 ER to Golgi Anterograde Transport 58/2473 154/10654 3.535103938105171e-5 1.0754240805056085e-4 4.653515278541993e-5 9919/84364/22820/6711/10342/2153/55291/2890/1783/2801/10484/10382/7039/10802/347688/5861/2157/830/7277/10381/1780/1781/90411/22872/966/8655/1315/11196/1639/832/55738/11316/22870/5265/8729/10376/51143/1314/9632/3630/4905/9276/6709/5537/9871/10383/6396/26286/1453/64689/288/26958/140735/10427/829/1778/22818/372 58 Human_SARS_coronavirus R-HSA-429914 Deadenylation-dependent mRNA decay 27/2473 56/10654 3.562227580110804e-5 1.0812779291840759e-4 4.6788457270202457e-5 1656/9924/80153/23644/27257/4849/25804/51690/4850/9652/255967/26986/28960/219988/4848/23019/55802/10767/196513/1975/55571/9775/54464/56915/85456/29883/80349 27 Human_SARS_coronavirus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 35/2473 80/10654 3.7091236015245367e-5 1.1233813645235462e-4 4.861033371116159e-5 8454/5718/1017/8945/5682/7321/5707/991/8697/5717/6500/5705/8881/7316/10213/891/890/4085/983/5714/51433/5701/5702/8900/29945/10393/6233/51434/701/7311/9184/5347/29882/7314/996 35 Human_SARS_coronavirus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 15/2473 24/10654 4.349369480757485e-5 1.309559699726677e-4 5.666653910126177e-5 6885/5606/23118/7316/9261/1432/10454/3654/7189/6233/7311/5600/5608/7314/257397 15 Human_SARS_coronavirus R-HSA-5654732 Negative regulation of FGFR3 signaling 17/2473 29/10654 4.352472471394787e-5 1.309559699726677e-4 5.666653910126177e-5 5594/7316/673/6714/8569/2261/867/2247/6233/2885/7311/5518/5781/7314/5595/5515/5516 17 Human_SARS_coronavirus R-HSA-72086 mRNA Capping 17/2473 29/10654 4.352472471394787e-5 1.309559699726677e-4 5.666653910126177e-5 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/2068/5439/5432/22916 17 Human_SARS_coronavirus R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 12/2473 17/10654 4.483603110287582e-5 1.3431230277979395e-4 5.8118872769528755e-5 7186/8737/356/355/841/7099/8797/8837/8772/8717/8795/148022 12 Human_SARS_coronavirus R-HSA-180292 GAB1 signalosome 12/2473 17/10654 4.483603110287582e-5 1.3431230277979395e-4 5.8118872769528755e-5 5295/685/5290/7039/1950/6714/55824/1445/2885/1956/5781/5829 12 Human_SARS_coronavirus R-HSA-112043 PLC beta mediated events 26/2473 54/10654 5.101110930234324e-5 1.5214617818003245e-4 6.583584816137663e-5 818/815/3838/5321/5575/5567/2770/817/5594/5568/112/3708/5573/111/3709/10768/5566/5576/816/5613/5577/5580/1385/3710/801/2773 26 Human_SARS_coronavirus R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 26/2473 54/10654 5.101110930234324e-5 1.5214617818003245e-4 6.583584816137663e-5 5295/54106/5170/4893/6464/5290/3667/2322/57761/2260/2263/2261/2247/3481/208/6654/2885/8660/9846/3479/5296/3845/3265/5781/30849/3480 26 Human_SARS_coronavirus R-HSA-4419969 Depolymerisation of the Nuclear Lamina 11/2473 15/10654 5.4678487829604444e-5 1.627307707206449e-4 7.041595418631558e-5 5579/255919/891/983/9663/2010/64900/23399/23592/23175/7112 11 Human_SARS_coronavirus R-HSA-917729 Endosomal Sorting Complex Required For Transport (ESCRT) 18/2473 32/10654 5.543446594422516e-5 1.646235655313353e-4 7.123499383126678e-5 137492/51652/25978/51160/8027/27243/91782/79720/7316/51271/9146/6233/7311/93343/7251/10254/92421/7314 18 Human_SARS_coronavirus R-HSA-193704 p75 NTR receptor-mediated signalling 40/2473 97/10654 5.589906848126913e-5 1.656447558451431e-4 7.167687762518084e-5 4804/57142/8841/4790/5584/10018/7531/572/57580/835/8878/1894/23421/23370/4615/7316/50650/5970/4792/5664/9138/836/4803/11108/3066/3065/3654/7189/6654/6233/7410/7409/7311/26574/387/5599/3551/5663/7314/5879 40 Human_SARS_coronavirus R-HSA-2132295 MHC class II antigen presentation 48/2473 123/10654 5.803680254230711e-5 1.7160882131044258e-4 7.42576148681062e-5 1173/164/162/1783/10484/10120/10382/10802/1174/347688/29127/1785/821/830/7277/10381/160/1780/1781/1509/22872/8655/1639/832/3796/10112/1062/10376/51143/9632/11004/163/9871/1213/10383/24137/84643/8905/6396/81930/7879/140735/8907/10427/829/1508/1778/1514 48 Human_SARS_coronavirus R-HSA-1250196 SHC1 events in ERBB2 signaling 14/2473 22/10654 5.9213385281109415e-5 1.7433640473322342e-4 7.543787959915454e-5 4893/6464/685/5782/2064/1950/2066/6654/2885/5580/1956/5581/3845/3265 14 Human_SARS_coronavirus R-HSA-9613829 Chaperone Mediated Autophagy 14/2473 22/10654 5.9213385281109415e-5 1.7433640473322342e-4 7.543787959915454e-5 1915/1080/10013/5116/7316/10226/3320/6233/3326/7311/7431/3312/11315/7314 14 Human_SARS_coronavirus R-HSA-111461 Cytochrome c-mediated apoptotic response 10/2473 13/10654 6.315929136054059e-5 1.847644941293426e-4 7.995026445369744e-5 842/5594/54205/56616/836/840/331/57099/317/5595 10 Human_SARS_coronavirus R-HSA-171007 p38MAPK events 10/2473 13/10654 6.315929136054059e-5 1.847644941293426e-4 7.995026445369744e-5 4893/9261/6714/5898/1432/5603/3845/5600/3265/6300 10 Human_SARS_coronavirus R-HSA-202670 ERKs are inactivated 10/2473 13/10654 6.315929136054059e-5 1.847644941293426e-4 7.995026445369744e-5 1849/5594/5528/5519/5598/5518/51231/5595/5515/5516 10 Human_SARS_coronavirus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 37/2473 88/10654 6.40971056758308e-5 1.871089978451912e-4 8.096476506420733e-5 5718/3303/5682/5707/3842/207/5717/3315/26986/5705/7534/8125/677/7538/7316/10213/9261/5714/8741/1432/5701/55802/5702/6233/5580/7514/7311/8021/54464/5600/56915/3312/8570/6418/7529/7314/1994 37 Human_SARS_coronavirus R-HSA-167169 HIV Transcription Elongation 23/2473 46/10654 6.53293429181065e-5 1.8949652956372543e-4 8.199788451276748e-5 2963/5434/5440/5430/5436/6749/5441/5438/5431/5435/4686/5433/9150/2962/5437/2068/5439/1025/904/51497/5432/22916/25920 23 Human_SARS_coronavirus R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 23/2473 46/10654 6.53293429181065e-5 1.8949652956372543e-4 8.199788451276748e-5 2963/5434/5440/5430/5436/6749/5441/5438/5431/5435/4686/5433/9150/2962/5437/2068/5439/1025/904/51497/5432/22916/25920 23 Human_SARS_coronavirus R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 23/2473 46/10654 6.53293429181065e-5 1.8949652956372543e-4 8.199788451276748e-5 2963/5434/5440/5430/5436/6749/5441/5438/5431/5435/4686/5433/9150/2962/5437/2068/5439/1025/904/51497/5432/22916/25920 23 Human_SARS_coronavirus R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 9/2473 11/10654 6.672584375703022e-5 1.913222892554762e-4 8.278791709382275e-5 7422/3091/10370/1387/2033/2056/2034/405/768 9 Human_SARS_coronavirus R-HSA-1433617 Regulation of signaling by NODAL 9/2473 11/10654 6.672584375703022e-5 1.913222892554762e-4 8.278791709382275e-5 55997/6997/7044/130399/4838/91/93/92/10637 9 Human_SARS_coronavirus R-HSA-8851805 MET activates RAS signaling 9/2473 11/10654 6.672584375703022e-5 1.913222892554762e-4 8.278791709382275e-5 4893/6464/10048/3082/4233/6654/2885/3845/3265 9 Human_SARS_coronavirus R-HSA-8934903 Receptor Mediated Mitophagy 9/2473 11/10654 6.672584375703022e-5 1.913222892554762e-4 8.278791709382275e-5 1459/9140/1460/9474/192111/1457/6714/8408/84557 9 Human_SARS_coronavirus R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 9/2473 11/10654 6.672584375703022e-5 1.913222892554762e-4 8.278791709382275e-5 627/4893/4915/4909/6654/2885/3845/3265/5781 9 Human_SARS_coronavirus R-HSA-8953750 Transcriptional Regulation by E2F6 19/2473 35/10654 6.679546396018447e-5 1.913222892554762e-4 8.278791709382275e-5 5888/83746/7027/2146/8317/6045/80012/5931/4149/1911/5928/10138/23512/1111/672/8726/8409/317/6015 19 Human_SARS_coronavirus R-HSA-2871837 FCERI mediated NF-kB activation 35/2473 82/10654 6.918323475763953e-5 1.9733762596149988e-4 8.539084014292308e-5 8454/1147/5718/5170/8945/2205/4790/6885/5682/7321/5707/5717/6500/23118/10892/5705/2206/7316/10213/5970/4792/8915/5714/5701/4067/10454/5702/7189/6233/7311/3551/997/2207/7314/257397 35 Human_SARS_coronavirus R-HSA-9013694 Signaling by NOTCH4 35/2473 82/10654 6.918323475763953e-5 1.9733762596149988e-4 8.539084014292308e-5 8454/5718/5682/2648/5707/23462/207/3280/5717/6500/5705/7534/7316/10213/9978/5714/5664/22938/8850/5701/1387/4088/59/2033/4855/55294/5702/9794/6233/7311/388585/3516/4851/5663/7314 35 Human_SARS_coronavirus R-HSA-2428928 IRS-related events triggered by IGF1R 25/2473 52/10654 7.307975243504839e-5 2.0758886198941282e-4 8.982669799142921e-5 5295/54106/5170/4893/5290/3667/2322/57761/2260/2263/2261/2247/3481/208/6654/2885/8660/9846/3479/5296/3845/3265/5781/30849/3480 25 Human_SARS_coronavirus R-HSA-383280 Nuclear Receptor transcription pathway 25/2473 52/10654 7.307975243504839e-5 2.0758886198941282e-4 8.982669799142921e-5 6095/5241/7182/5468/3172/5915/2516/6097/5465/2100/4306/9611/5469/2063/9612/2099/7101/5467/2908/3164/6256/367/8431/7421/10062 25 Human_SARS_coronavirus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 33/2473 76/10654 7.35546537547142e-5 2.0850616725509894e-4 9.02236292250083e-5 5718/5682/7321/5707/991/8697/5717/5705/8881/7316/10213/891/890/4085/983/5714/51433/5701/5702/8900/29945/10393/4751/9232/6233/51434/701/7311/9184/5347/29882/7314/996 33 Human_SARS_coronavirus R-HSA-112040 G-protein mediated events 26/2473 55/10654 7.55545468682892e-5 2.1373368722328408e-4 9.248565259623463e-5 818/815/3838/5321/5575/5567/2770/817/5594/5568/112/3708/5573/111/3709/10768/5566/5576/816/5613/5577/5580/1385/3710/801/2773 26 Human_SARS_coronavirus R-HSA-111996 Ca-dependent events 20/2473 38/10654 7.715647149077454e-5 2.1781621169823594e-4 9.425221988476683e-5 818/815/3838/5321/5575/5567/817/5594/5568/112/5573/111/5566/5576/816/5613/5577/5580/1385/801 20 Human_SARS_coronavirus R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 13/2473 20/10654 7.97922999456012e-5 2.2296341247528482e-4 9.647948798224693e-5 7321/991/8697/8881/4085/51433/29945/10393/51434/701/9184/29882/996 13 Human_SARS_coronavirus R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 13/2473 20/10654 7.97922999456012e-5 2.2296341247528482e-4 9.647948798224693e-5 7321/991/8697/8881/4085/51433/29945/10393/51434/701/9184/29882/996 13 Human_SARS_coronavirus R-HSA-164938 Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 13/2473 20/10654 7.97922999456012e-5 2.2296341247528482e-4 9.647948798224693e-5 1173/164/162/1174/160/567/926/163/3932/8905/55690/8907/940 13 Human_SARS_coronavirus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 13/2473 20/10654 7.97922999456012e-5 2.2296341247528482e-4 9.647948798224693e-5 1147/7321/8737/330/7323/7316/329/7189/6233/7311/3551/7314/148022 13 Human_SARS_coronavirus R-HSA-5625900 RHO GTPases activate CIT 13/2473 20/10654 7.97922999456012e-5 2.2296341247528482e-4 9.647948798224693e-5 4659/4627/389/1027/10627/10398/4637/4628/103910/387/4660/5500/5879 13 Human_SARS_coronavirus R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 15/2473 25/10654 8.542280456598569e-5 2.3821156070026904e-4 1.0307758188963614e-4 23286/2648/23462/3280/6772/22938/8850/5087/1387/26508/2033/9794/388585/3516/4851 15 Human_SARS_coronavirus R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 22/2473 44/10654 9.387400099049629e-5 2.6124772689444404e-4 1.1304566362472489e-4 23368/834/27113/79370/835/355/472/332/5366/8797/1387/7157/8626/604/7161/581/7159/637/317/10397/8795/665 22 Human_SARS_coronavirus R-HSA-180910 Vpr-mediated nuclear import of PICs 18/2473 33/10654 9.559966264017594e-5 2.6497522655014423e-4 1.1465860654770704e-4 4928/5903/3159/348995/79023/57122/23636/23279/4927/79902/23225/8086/3836/9972/8021/6396/55746/8480 18 Human_SARS_coronavirus R-HSA-1839126 FGFR2 mutant receptor activation 18/2473 33/10654 9.559966264017594e-5 2.6497522655014423e-4 1.1465860654770704e-4 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2263/2962/5437/2247/5439/5432/22916 18 Human_SARS_coronavirus R-HSA-9020591 Interleukin-12 signaling 23/2473 47/10654 1.0003554292172155e-4 2.767112195334717e-4 1.1973694016946299e-4 3592/6627/27250/3593/6775/3595/3313/6175/6647/5898/6950/3717/3458/998/6648/3716/3594/2939/302/7297/5062/3586/829 23 Human_SARS_coronavirus R-HSA-210993 Tie2 Signaling 12/2473 18/10654 1.0603087048559456e-4 2.921171773217585e-4 1.2640332055353063e-4 5295/4893/6464/5290/7010/6654/2885/5296/3845/3265/5781/9046 12 Human_SARS_coronavirus R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 12/2473 18/10654 1.0603087048559456e-4 2.921171773217585e-4 1.2640332055353063e-4 4893/5594/4314/5598/6654/2885/1385/6196/1956/3845/3265/5595 12 Human_SARS_coronavirus R-HSA-70171 Glycolysis 31/2473 71/10654 1.0625052900713735e-4 2.921357230416682e-4 1.2641134555432015e-4 4928/5903/2597/5315/5567/5568/348995/79023/57122/23636/5528/5230/3098/23279/4927/79902/5566/5519/226/23225/8086/9972/5518/8021/6396/230/55746/10007/8480/5515/5516 31 Human_SARS_coronavirus R-HSA-373760 L1CAM interactions 46/2473 119/10654 1.0728374997894125e-4 2.9438660994221484e-4 1.2738533681710078e-4 1173/9252/6711/71/5604/1459/10048/10382/5594/347688/1785/1460/7277/10381/2260/160/3912/3688/4684/3672/8650/1272/1457/3915/6714/5605/3690/1808/10376/1641/2048/7410/6709/3685/163/6196/1213/10383/24137/1956/60/3312/5058/288/5879/5595 46 Human_SARS_coronavirus R-HSA-373755 Semaphorin interactions 29/2473 65/10654 1.1014548008243905e-4 3.016359254952223e-4 1.3052222033090792e-4 7305/4627/389/10627/2064/5788/3688/3672/971/10398/9855/4233/2932/4637/3320/2534/9475/1808/4628/3326/6093/103910/387/8851/5058/1020/5062/5879/2242 29 Human_SARS_coronavirus R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 16/2473 28/10654 1.118669660092737e-4 3.051321617588937e-4 1.3203509224491027e-4 10694/10575/10382/7277/10381/7203/10576/908/10471/6950/10574/10383/60/22948/10693/5202 16 Human_SARS_coronavirus R-HSA-75067 Processing of Capped Intronless Pre-mRNA 16/2473 28/10654 1.118669660092737e-4 3.051321617588937e-4 1.3203509224491027e-4 53981/134353/79869/29894/81608/4686/8189/1478/10898/51692/23283/6634/10914/22916/1479/55339 16 Human_SARS_coronavirus R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 20/2473 39/10654 0.00012402085648845305 3.3761233155189997e-4 1.4608973070068406e-4 10694/8841/22803/8237/10575/10517/7203/10576/908/6774/26985/26270/6950/55294/10238/7157/10574/54461/22948/10693 20 Human_SARS_coronavirus R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 11/2473 16/10654 1.3815033891297445e-4 3.7458945649921136e-4 1.620902665839767e-4 7027/286826/5934/1875/890/983/5933/5928/1874/3065/55957 11 Human_SARS_coronavirus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 11/2473 16/10654 1.3815033891297445e-4 3.7458945649921136e-4 1.620902665839767e-4 6885/23118/7099/7316/10454/7189/6233/7311/7314/148022/257397 11 Human_SARS_coronavirus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 32/2473 75/10654 1.407977615779341e-4 3.8101484987164815e-4 1.648706270735074e-4 5718/5682/7321/5707/991/8697/5717/5705/8881/7316/10213/891/890/4085/983/5714/51433/5701/5702/8900/29945/10393/4751/9232/6233/51434/701/7311/9184/29882/7314/996 32 Human_SARS_coronavirus R-HSA-199992 trans-Golgi Network Vesicle Budding 31/2473 72/10654 1.4555978406864128e-4 3.9312603098853513e-4 1.701113100180557e-4 23557/2512/164/351/8906/162/84062/9685/9179/1176/27243/1174/1785/8546/55330/8301/7037/9698/9146/8729/4074/408/388552/5878/10717/1213/8905/23431/3312/8907/4952 31 Human_SARS_coronavirus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 18/2473 34/10654 1.5929209317420834e-4 4.2936886411594076e-4 1.857941072283187e-4 7321/9140/29110/9636/54476/7706/7323/9474/7316/7128/83737/3661/51191/6233/7311/5300/1540/7314 18 Human_SARS_coronavirus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 13/2473 21/10654 1.649498497946638e-4 4.437474390554485e-4 1.920159242191752e-4 1147/4790/8737/29110/4615/5970/4792/4793/1660/3661/3551/4791/148022 13 Human_SARS_coronavirus R-HSA-202424 Downstream TCR signaling 39/2473 98/10654 1.713365107029938e-4 4.6002679586009293e-4 1.9906023696876818e-4 5295/8454/1147/5718/5170/8945/3635/5290/4790/6885/5682/7321/5707/5717/6500/23118/10892/5705/919/7316/10213/5970/4792/8915/5714/5701/915/917/5728/916/5702/7189/6233/7311/3932/5296/3551/997/7314 39 Human_SARS_coronavirus R-HSA-180336 SHC1 events in EGFR signaling 10/2473 14/10654 1.7486484913370188e-4 4.640513984747369e-4 2.008017406320022e-4 4893/6464/685/7039/1950/6654/2885/1956/3845/3265 10 Human_SARS_coronavirus R-HSA-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase 10/2473 14/10654 1.7486484913370188e-4 4.640513984747369e-4 2.008017406320022e-4 5575/5567/5568/5573/5566/5576/5613/5577/1385/801 10 Human_SARS_coronavirus R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 10/2473 14/10654 1.7486484913370188e-4 4.640513984747369e-4 2.008017406320022e-4 23368/207/54971/10848/10000/7157/8626/208/7161/7159 10 Human_SARS_coronavirus R-HSA-8941856 RUNX3 regulates NOTCH signaling 10/2473 14/10654 1.7486484913370188e-4 4.640513984747369e-4 2.008017406320022e-4 2648/864/3280/22938/8850/1387/2033/9794/3516/4851 10 Human_SARS_coronavirus R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 10/2473 14/10654 1.7486484913370188e-4 4.640513984747369e-4 2.008017406320022e-4 8841/79718/9611/2874/9612/5566/6907/3065/25942/801 10 Human_SARS_coronavirus R-HSA-9005895 Pervasive developmental disorders 10/2473 14/10654 1.7486484913370188e-4 4.640513984747369e-4 2.008017406320022e-4 8841/79718/9611/2874/9612/5566/6907/3065/25942/801 10 Human_SARS_coronavirus R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 19/2473 37/10654 1.785240980464714e-4 4.728476110420053e-4 2.0460798881977214e-4 27161/8841/79718/57690/27327/192670/9611/2874/9612/6907/2033/192669/23028/6256/23112/4343/26523/8648/10062 19 Human_SARS_coronavirus R-HSA-162588 Budding and maturation of HIV virion 16/2473 29/10654 1.9598049375736893e-4 5.170869950675195e-4 2.2375100906711756e-4 137492/51652/25978/51160/27243/91782/79720/7316/51271/23327/6233/7311/93343/7251/92421/7314 16 Human_SARS_coronavirus R-HSA-5205647 Mitophagy 16/2473 29/10654 1.9598049375736893e-4 5.170869950675195e-4 2.2375100906711756e-4 65018/1459/9140/8878/1460/7416/9474/192111/7316/1457/6714/8408/6233/7311/84557/7314 16 Human_SARS_coronavirus R-HSA-2029481 FCGR activation 9/2473 12/10654 2.1159321247245444e-4 5.550781787996319e-4 2.4019034282874973e-4 2268/919/3055/6850/6714/4067/917/2534/7525 9 Human_SARS_coronavirus R-HSA-3371511 HSF1 activation 9/2473 12/10654 2.1159321247245444e-4 5.550781787996319e-4 2.4019034282874973e-4 6118/7531/1915/10013/7415/6119/3320/3326/6117 9 Human_SARS_coronavirus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 9/2473 12/10654 2.1159321247245444e-4 5.550781787996319e-4 2.4019034282874973e-4 3665/29110/7316/3661/6233/10010/7311/7314/148022 9 Human_SARS_coronavirus R-HSA-933542 TRAF6 mediated NF-kB activation 14/2473 24/10654 2.2474885411294604e-4 5.884645569522175e-4 2.546371107266002e-4 1147/351/7186/4790/4214/7706/5970/4792/4793/3146/6288/7189/3551/4791 14 Human_SARS_coronavirus R-HSA-176412 Phosphorylation of the APC/C 12/2473 19/10654 2.2697887208618375e-4 5.931714523852269e-4 2.566738523440755e-4 7321/8697/8881/891/983/51433/29945/10393/51434/5347/29882/996 12 Human_SARS_coronavirus R-HSA-381042 PERK regulates gene expression 17/2473 32/10654 2.2914567087272187e-4 5.965614050045055e-4 2.581407337905026e-4 440/1965/4802/1051/1649/3576/468/4800/1054/8894/3309/9451/6347/467/56915/8570/1968 17 Human_SARS_coronavirus R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 17/2473 32/10654 2.2914567087272187e-4 5.965614050045055e-4 2.581407337905026e-4 10694/10575/10382/7277/10381/7203/10576/908/10471/6950/10376/10574/10383/60/22948/10693/5202 17 Human_SARS_coronavirus R-HSA-8853334 Signaling by FGFR3 fusions in cancer 8/2473 10/10654 2.3731298060802744e-4 6.154884865675116e-4 2.663307552739578e-4 5295/4893/5290/2261/6654/2885/3845/3265 8 Human_SARS_coronavirus R-HSA-8877330 RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) 8/2473 10/10654 2.3731298060802744e-4 6.154884865675116e-4 2.663307552739578e-4 4773/865/3558/50943/3458/861/3559/1493 8 Human_SARS_coronavirus R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 15/2473 27/10654 2.8069287697152944e-4 7.25255418465044e-4 3.138284916482161e-4 2963/5434/5440/5430/5436/5441/5438/5431/5435/5433/2962/5437/2068/5439/5432 15 Human_SARS_coronavirus R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 15/2473 27/10654 2.8069287697152944e-4 7.25255418465044e-4 3.138284916482161e-4 2963/5434/5440/5430/5436/5441/5438/5431/5435/5433/2962/5437/2068/5439/5432 15 Human_SARS_coronavirus R-HSA-74158 RNA Polymerase III Transcription 20/2473 41/10654 2.971986600450902e-4 7.650216915231965e-4 3.310359321920231e-4 55718/5434/5440/2971/5451/9330/4774/5441/5435/55703/9328/5437/4782/7702/6908/661/6619/4784/6618/11128 20 Human_SARS_coronavirus R-HSA-749476 RNA Polymerase III Abortive And Retractive Initiation 20/2473 41/10654 2.971986600450902e-4 7.650216915231965e-4 3.310359321920231e-4 55718/5434/5440/2971/5451/9330/4774/5441/5435/55703/9328/5437/4782/7702/6908/661/6619/4784/6618/11128 20 Human_SARS_coronavirus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 34/2473 84/10654 3.0010221658943276e-4 7.710491407503778e-4 3.3364409650392293e-4 9318/6118/10445/7515/6613/7507/8450/54778/7316/9978/5425/5111/10980/6119/29844/7341/10401/1642/142/2068/10987/7329/6233/7311/3980/60/8607/6117/10714/5424/7314/8451/8554/7528 34 Human_SARS_coronavirus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 11/2473 17/10654 3.092265698981565e-4 7.900537316578599e-4 3.4186765739990257e-4 1147/4790/8737/4615/5970/4792/4793/1660/3551/4791/148022 11 Human_SARS_coronavirus R-HSA-4655427 SUMOylation of DNA methylation proteins 11/2473 17/10654 3.092265698981565e-4 7.900537316578599e-4 3.4186765739990257e-4 1912/8535/1786/6045/80012/1911/7341/84733/57332/7329/6015 11 Human_SARS_coronavirus R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 11/2473 17/10654 3.092265698981565e-4 7.900537316578599e-4 3.4186765739990257e-4 6885/23118/7099/7316/10454/7189/6233/7311/7314/148022/257397 11 Human_SARS_coronavirus R-HSA-73762 RNA Polymerase I Transcription Initiation 22/2473 47/10654 3.17181658812148e-4 8.071432770222775e-4 3.492625504377509e-4 5434/5440/2648/9112/9219/5931/5441/5435/7270/1108/8850/5928/5437/57459/54815/2068/3066/3065/1107/57504/6908/53615 22 Human_SARS_coronavirus R-HSA-9024446 NR1H2 and NR1H3-mediated signaling 22/2473 47/10654 3.17181658812148e-4 8.071432770222775e-4 3.492625504377509e-4 27161/8841/79718/8204/57690/27327/192670/9611/2874/2194/9612/5346/6907/2033/192669/23028/6256/23112/4343/26523/8648/10062 22 Human_SARS_coronavirus R-HSA-140875 Common Pathway of Fibrin Clot Formation 13/2473 22/10654 3.176802985364649e-4 8.071432770222775e-4 3.492625504377509e-4 2149/2153/5657/2157/5196/2244/2162/5624/2266/2243/10544/2147/5627 13 Human_SARS_coronavirus R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 25/2473 56/10654 3.183247378662833e-4 8.07285656843883e-4 3.4932416024240456e-4 8841/79718/200186/5465/4209/9611/5469/54205/64784/4208/1387/6604/6907/6648/6256/10498/1385/10499/23054/1386/3054/801/23373/8648/96764 25 Human_SARS_coronavirus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 16/2473 30/10654 3.29924289016171e-4 8.336208554883733e-4 3.6071978095399913e-4 6118/56852/8450/7316/9978/5425/5111/6119/1642/6233/7311/6117/10714/5424/7314/8451 16 Human_SARS_coronavirus R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 16/2473 30/10654 3.29924289016171e-4 8.336208554883733e-4 3.6071978095399913e-4 818/5170/815/4893/2904/817/5594/2902/816/88/1385/6196/3845/3265/801/5595 16 Human_SARS_coronavirus R-HSA-391251 Protein folding 39/2473 101/10654 3.571074625734481e-4 9.006460269315639e-4 3.8972254042458345e-4 10694/8841/22803/59345/1459/2770/8237/10575/10382/1460/7277/10381/10517/7203/10576/908/6774/1457/10471/26985/1155/26270/6950/10376/55294/2783/10238/2782/5082/7157/10574/10383/60/54461/22948/10693/6904/2773/5202 39 Human_SARS_coronavirus R-HSA-5617833 Cilium Assembly 68/2473 201/10654 3.592481588620102e-4 9.043825210250972e-4 3.913393753706881e-4 6102/115106/10694/55763/79738/55559/22981/7531/54903/80776/10142/203068/3842/54801/7532/10575/1454/10382/347688/95681/121441/7277/79441/10013/10381/5116/79989/7203/5048/1781/23354/10576/8655/83658/9738/79598/983/1639/89891/5566/84131/6950/55212/7283/3320/8729/22919/10376/4751/5577/54930/5518/10383/54820/5347/22948/9662/55142/23332/1453/9793/140735/93323/51259/55755/9657/57576/1778 68 Human_SARS_coronavirus R-HSA-5654726 Negative regulation of FGFR1 signaling 17/2473 33/10654 3.7103830461980336e-4 9.32352662890788e-4 4.034424596213016e-4 5594/2260/7316/673/6714/8569/867/2247/6233/2885/7311/5518/5781/7314/5595/5515/5516 17 Human_SARS_coronavirus R-HSA-216083 Integrin cell surface interactions 34/2473 85/10654 3.901225796399699e-4 9.785158670311495e-4 4.2341794461068605e-4 960/3696/7412/3684/3383/1277/1280/7448/6696/50848/3688/3672/3693/1281/999/2244/682/2335/3690/3694/2200/2266/3685/4060/8516/2243/3791/7450/3687/7057/1278/3689/1296/3676 34 Human_SARS_coronavirus R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 14/2473 25/10654 4.020729171727146e-4 0.0010048161063041245 4.347984378974423e-4 10694/10575/10382/7277/10381/7203/10576/908/6950/10376/10574/10383/22948/10693 14 Human_SARS_coronavirus R-HSA-937041 IKK complex recruitment mediated by RIP1 14/2473 25/10654 4.020729171727146e-4 0.0010048161063041245 4.347984378974423e-4 1147/7321/8737/330/7099/7323/7316/329/7189/6233/7311/3551/7314/148022 14 Human_SARS_coronavirus R-HSA-111933 Calmodulin induced events 18/2473 36/10654 4.0363756457033095e-4 0.0010050648613257607 4.349060777871176e-4 818/815/3838/5575/5567/817/5568/112/5573/111/5566/5576/816/5613/5577/5580/1385/801 18 Human_SARS_coronavirus R-HSA-111997 CaM pathway 18/2473 36/10654 4.0363756457033095e-4 0.0010050648613257607 4.349060777871176e-4 818/815/3838/5575/5567/817/5568/112/5573/111/5566/5576/816/5613/5577/5580/1385/801 18 Human_SARS_coronavirus R-HSA-390466 Chaperonin-mediated protein folding 37/2473 95/10654 4.111231405122069e-4 0.0010218495448962824 4.4216905272479926e-4 10694/8841/22803/59345/1459/2770/8237/10575/10382/1460/7277/10381/10517/7203/10576/908/6774/1457/10471/26985/26270/6950/10376/55294/2783/10238/2782/5082/7157/10574/10383/60/54461/22948/10693/2773/5202 37 Human_SARS_coronavirus R-HSA-354194 GRB2:SOS provides linkage to MAPK signaling for Integrins 10/2473 15/10654 4.152375717418966e-4 0.00102835008741856 4.449819313365565e-4 5747/6714/2244/2335/3690/6654/2885/2266/2243/7450 10 Human_SARS_coronavirus R-HSA-430039 mRNA decay by 5' to 3' exoribonuclease 10/2473 15/10654 4.152375717418966e-4 0.00102835008741856 4.449819313365565e-4 1656/80153/23644/27257/25804/51690/219988/55802/196513/54464 10 Human_SARS_coronavirus R-HSA-6784531 tRNA processing in the nucleus 25/2473 57/10654 4.433868158622132e-4 0.0010960841646179397 4.742914445638469e-4 60528/4928/5903/29894/348995/79023/57122/23636/283742/1478/11260/23279/4927/79902/10898/23225/5901/8086/1653/9972/8021/6396/55746/51493/8480 25 Human_SARS_coronavirus R-HSA-2426168 Activation of gene expression by SREBF (SREBP) 20/2473 42/10654 4.4465800047569165e-4 0.0010972495982961314 4.747957445442827e-4 79718/4802/6721/5465/5469/2194/4800/6667/1387/6604/6907/6256/4047/10498/10499/23054/2224/31/8648/96764 20 Human_SARS_coronavirus R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 12/2473 20/10654 0.00044775873029705686 0.0011029173751661795 4.772482734338847e-4 23368/27113/472/5366/1387/7157/8626/7161/581/7159/637/665 12 Human_SARS_coronavirus R-HSA-112399 IRS-mediated signalling 22/2473 48/10654 4.584634026041694e-4 0.0011272612694855203 4.8778222801122717e-4 5295/54106/5170/4893/5290/3667/2322/57761/2260/2263/2261/2247/208/6654/2885/8660/9846/5296/3845/3265/5781/30849 22 Human_SARS_coronavirus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 30/2473 73/10654 4.905777257992231e-4 0.0012019154282080966 5.200861604337629e-4 5718/5682/7321/5707/991/8697/5717/5705/8881/7316/10213/890/4085/983/5714/51433/5701/5702/8900/29945/10393/4751/6233/51434/701/7311/9184/29882/7314/996 30 Human_SARS_coronavirus R-HSA-8939902 Regulation of RUNX2 expression and activity 30/2473 73/10654 4.905777257992231e-4 0.0012019154282080966 5.200861604337629e-4 8454/57154/5718/7291/5682/5707/10273/5717/6500/5705/7316/10213/9978/865/11059/579/5714/6772/2099/2932/5701/6502/650/2908/55294/5702/6233/7311/860/7314 30 Human_SARS_coronavirus R-HSA-8856688 Golgi-to-ER retrograde transport 48/2473 133/10654 5.094569047134598e-4 0.0012459445156272136 5.39138182303014e-4 55582/84364/22820/5321/1783/10382/347688/29127/5861/830/7277/10381/23299/1780/5048/1781/8655/1315/1639/832/55738/3796/9183/10112/11316/636/1062/662/8729/10376/51143/1314/4905/23303/11004/9276/10383/24137/84643/5049/26286/81930/26958/140735/829/1778/22818/372 48 Human_SARS_coronavirus R-HSA-983231 Factors involved in megakaryocyte development and platelet production 58/2473 168/10654 5.317104224574641e-4 0.001298054625643489 5.616869793332268e-4 55582/1017/57572/25/2624/85440/5868/23348/5575/23186/5567/10382/2625/347688/5568/29127/830/7277/10381/3048/5573/832/3659/5566/3796/23414/10112/1062/3705/3717/5576/10376/3066/3065/998/7157/7975/23028/23303/11004/5577/2626/10383/24137/51317/4097/60/25942/84643/7465/3456/1020/81704/81930/10362/3660/829/5879 58 Human_SARS_coronavirus R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 16/2473 31/10654 5.358578311619929e-4 0.0013012335298305385 5.630625370756665e-4 4928/5903/348995/79023/57122/23636/23279/4927/79902/23225/8086/9972/8021/6396/55746/8480 16 Human_SARS_coronavirus R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 16/2473 31/10654 5.358578311619929e-4 0.0013012335298305385 5.630625370756665e-4 4928/5903/348995/79023/57122/23636/23279/4927/79902/23225/8086/9972/8021/6396/55746/8480 16 Human_SARS_coronavirus R-HSA-5654733 Negative regulation of FGFR4 signaling 16/2473 31/10654 5.358578311619929e-4 0.0013012335298305385 5.630625370756665e-4 5594/7316/673/6714/8569/867/2247/6233/2885/7311/5518/5781/7314/5595/5515/5516 16 Human_SARS_coronavirus R-HSA-1169091 Activation of NF-kappaB in B cells 28/2473 67/10654 5.413637609591273e-4 0.001312281060134139 5.678429629550825e-4 8454/1147/5718/8945/4790/6885/5579/5966/5682/5707/5717/6500/10892/5705/7316/10213/5970/4792/4793/8915/5714/5701/5702/6233/7311/4794/3551/7314 28 Human_SARS_coronavirus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 9/2473 13/10654 5.455695349742625e-4 0.0013131954420784002 5.682386292252706e-4 207/9101/2064/7316/10000/208/6233/7311/7314 9 Human_SARS_coronavirus R-HSA-179812 GRB2 events in EGFR signaling 9/2473 13/10654 5.455695349742625e-4 0.0013131954420784002 5.682386292252706e-4 4893/685/7039/1950/6654/2885/1956/3845/3265 9 Human_SARS_coronavirus R-HSA-5210891 Uptake and function of anthrax toxins 9/2473 13/10654 5.455695349742625e-4 0.0013131954420784002 5.682386292252706e-4 5606/5604/5045/5605/118429/5609/801/6416/5608 9 Human_SARS_coronavirus R-HSA-68884 Mitotic Telophase/Cytokinesis 9/2473 13/10654 5.455695349742625e-4 0.0013131954420784002 5.682386292252706e-4 10274/23244/10735/23047/5885/10112/8243/9126/5347 9 Human_SARS_coronavirus R-HSA-5654727 Negative regulation of FGFR2 signaling 17/2473 34/10654 5.82784516065397e-4 0.0014003158599679942 6.059368919916747e-4 5594/7316/673/2263/6714/8569/867/2247/6233/2885/7311/5518/5781/7314/5595/5515/5516 17 Human_SARS_coronavirus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 11/2473 18/10654 6.285340975464674e-4 0.0015076027654436245 6.523614851236798e-4 3665/29110/7099/7316/3661/6233/10010/7311/5781/7314/148022 11 Human_SARS_coronavirus R-HSA-2172127 DAP12 interactions 20/2473 43/10654 6.516880725027593e-4 0.0015576934415919613 6.740364439603087e-4 5295/4893/6464/5290/5335/7305/5336/567/6850/27040/2534/695/6654/2885/7410/3932/5296/3845/3265/5879 20 Human_SARS_coronavirus R-HSA-5696395 Formation of Incision Complex in GG-NER 20/2473 43/10654 6.516880725027593e-4 0.0015576934415919613 6.740364439603087e-4 6118/6613/7507/8450/54778/7316/9978/6119/7341/10401/1642/142/2068/7329/6233/7311/6117/7314/8451/8554 20 Human_SARS_coronavirus R-HSA-111458 Formation of apoptosome 8/2473 11/10654 6.922120122106864e-4 0.0016402674969828355 7.09767430027865e-4 842/5594/54205/56616/331/57099/317/5595 8 Human_SARS_coronavirus R-HSA-2025928 Calcineurin activates NFAT 8/2473 11/10654 6.922120122106864e-4 0.0016402674969828355 7.09767430027865e-4 4773/4772/5532/4775/5530/5534/2280/801 8 Human_SARS_coronavirus R-HSA-2468052 Establishment of Sister Chromatid Cohesion 8/2473 11/10654 6.922120122106864e-4 0.0016402674969828355 7.09767430027865e-4 10274/23244/10735/23047/5885/8243/9126/113130 8 Human_SARS_coronavirus R-HSA-5655291 Signaling by FGFR4 in disease 8/2473 11/10654 6.922120122106864e-4 0.0016402674969828355 7.09767430027865e-4 5295/4893/5290/5335/6654/2885/3845/3265 8 Human_SARS_coronavirus R-HSA-9627069 Regulation of the apoptosome activity 8/2473 11/10654 6.922120122106864e-4 0.0016402674969828355 7.09767430027865e-4 842/5594/54205/56616/331/57099/317/5595 8 Human_SARS_coronavirus R-HSA-6807878 COPI-mediated anterograde transport 38/2473 101/10654 7.622275028348287e-4 0.0018030622998092844 7.802110918309318e-4 84364/22820/6711/1783/2801/10382/347688/5861/830/7277/10381/1780/1781/966/8655/1315/1639/832/55738/11316/8729/10376/51143/1314/3630/4905/9276/6709/10383/26286/64689/288/26958/140735/829/1778/22818/372 38 Human_SARS_coronavirus R-HSA-111931 PKA-mediated phosphorylation of CREB 12/2473 21/10654 8.248372376335815e-4 0.0019478084165805056 8.428448265700516e-4 5575/5567/5568/112/5573/111/5566/5576/5613/5577/1385/801 12 Human_SARS_coronavirus R-HSA-3000171 Non-integrin membrane-ECM interactions 25/2473 59/10654 8.274059112822808e-4 0.0019505170279712873 8.440168818289138e-4 6385/3911/1277/6383/1280/3912/7448/3688/1756/3915/3693/1281/2247/1605/2335/3690/87/3913/3685/5155/6382/7040/7057/1278/3691 25 Human_SARS_coronavirus R-HSA-1234174 Cellular response to hypoxia 30/2473 75/10654 8.387648081237987e-4 0.001973902773148974 8.541362314377944e-4 5718/5682/112399/7321/5707/84962/7422/5717/3091/5705/7323/7316/10213/9978/5714/8994/10370/5701/1387/2033/5702/8453/6233/2056/7311/2034/55662/405/768/7314 30 Human_SARS_coronavirus R-HSA-948021 Transport to the Golgi and subsequent modification 62/2473 185/10654 8.403701323017655e-4 0.00197429421492812 8.543056139477212e-4 9919/84364/22820/6711/10342/2153/55291/2890/1783/2530/2801/10484/10382/7039/10802/347688/5861/2157/830/7277/10381/1780/1781/90411/22872/966/8655/1315/11196/1639/832/55738/11316/57134/22870/5265/8729/10376/51143/1314/9632/3630/4905/4245/9276/6709/5537/9871/10383/6396/26286/1453/64689/288/26958/140735/10427/10905/829/1778/22818/372 62 Human_SARS_coronavirus R-HSA-5626467 RHO GTPases activate IQGAPs 16/2473 32/10654 8.42569991451269e-4 0.0019760786808053696 8.550777780989936e-4 71/6249/1499/10382/347688/7277/10381/999/10376/998/8826/10383/60/801/5879/4221 16 Human_SARS_coronavirus R-HSA-432722 Golgi Associated Vesicle Biogenesis 24/2473 56/10654 8.595284547306645e-4 0.002012411330871112 8.707994403953563e-4 23557/2512/164/162/84062/9685/1176/1174/1785/8546/55330/8301/7037/9698/408/388552/5878/10717/1213/8905/23431/3312/8907/4952 24 Human_SARS_coronavirus R-HSA-1963640 GRB2 events in ERBB2 signaling 10/2473 16/10654 8.77049626456765e-4 0.0020464491283991187 8.855280868628992e-4 4893/685/2064/1950/2066/6654/2885/1956/3845/3265 10 Human_SARS_coronavirus R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 10/2473 16/10654 8.77049626456765e-4 0.0020464491283991187 8.855280868628992e-4 2648/3280/22938/8850/1387/2033/9794/3516/4851/6928 10 Human_SARS_coronavirus R-HSA-432720 Lysosome Vesicle Biogenesis 17/2473 35/10654 8.902529529152668e-4 0.0020737301381999087 8.973329737185426e-4 164/351/8906/162/9179/27243/1174/1785/9146/4074/408/10717/1213/8905/23431/3312/8907 17 Human_SARS_coronavirus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 29/2473 72/10654 8.917690492945366e-4 0.002073740907851024 8.973376339020851e-4 5718/5682/7321/5707/991/8697/5717/5705/8881/7316/10213/890/4085/983/5714/51433/5701/5702/8900/29945/10393/6233/51434/701/7311/9184/29882/7314/996 29 Human_SARS_coronavirus R-HSA-373752 Netrin-1 signaling 22/2473 50/10654 9.114439469846747e-4 0.0021159070985837117 9.155835534764566e-4 5335/5747/4690/4651/285704/6478/6477/7220/6714/56963/1432/2534/5603/998/8976/5599/5600/3983/5058/6300/5781/5879 22 Human_SARS_coronavirus R-HSA-8875878 MET promotes cell motility 19/2473 41/10654 9.349272582480148e-4 0.0021667570917504667 9.375870797508542e-4 85440/5747/3911/3082/1277/1280/3912/3688/4233/3915/6714/1281/2335/64759/3913/2885/1398/1278/5879 19 Human_SARS_coronavirus R-HSA-449836 Other interleukin signaling 13/2473 24/10654 9.909906387980407e-4 0.0022851078259343055 9.887991513172843e-4 6804/5657/1436/1435/1441/1440/836/163702/3716/282618/6382/3588/7297 13 Human_SARS_coronavirus R-HSA-5260271 Diseases of Immune System 13/2473 24/10654 9.909906387980407e-4 0.0022851078259343055 9.887991513172843e-4 1147/4790/7099/4615/5970/4792/114609/695/81622/7097/3551/4791/148022 13 Human_SARS_coronavirus R-HSA-5602358 Diseases associated with the TLR signaling cascade 13/2473 24/10654 9.909906387980407e-4 0.0022851078259343055 9.887991513172843e-4 1147/4790/7099/4615/5970/4792/114609/695/81622/7097/3551/4791/148022 13 Human_SARS_coronavirus R-HSA-3000178 ECM proteoglycans 30/2473 76/10654 0.0010825817117413516 0.002492117631726736 0.0010783752833311948 351/633/6678/7042/3911/1634/1277/54829/1280/3912/7448/3688/4684/3915/3693/1281/1605/2335/3690/3694/3913/3685/4060/8516/7040/3687/2331/1278/7043/5054 30 Human_SARS_coronavirus R-HSA-5628897 TP53 Regulates Metabolic Genes 33/2473 86/10654 0.001115217267931206 0.002562944877054631 0.0011090232550704402 27161/7531/7532/207/10971/57690/7249/27327/7295/7533/2810/192670/7534/2539/54205/64223/5571/10000/10128/5728/192669/7157/8626/23112/208/10542/2475/5562/4513/4343/26523/57521/7529 33 Human_SARS_coronavirus R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 14/2473 27/10654 0.0011225514916972858 0.002575486031118187 0.0011144499935174604 7186/842/8737/356/355/841/7099/8797/836/8837/8772/8717/8795/148022 14 Human_SARS_coronavirus R-HSA-169893 Prolonged ERK activation events 9/2473 14/10654 0.0012128379694872717 0.0027595583650688836 0.0011941007502676464 5604/5594/673/5605/4914/4803/1398/7529/5595 9 Human_SARS_coronavirus R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 9/2473 14/10654 0.0012128379694872717 0.0027595583650688836 0.0011941007502676464 6118/4436/5425/5111/5395/6119/6117/10714/5424 9 Human_SARS_coronavirus R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 9/2473 14/10654 0.0012128379694872717 0.0027595583650688836 0.0011941007502676464 6118/4436/5425/5111/5395/6119/6117/10714/5424 9 Human_SARS_coronavirus R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 9/2473 14/10654 0.0012128379694872717 0.0027595583650688836 0.0011941007502676464 23368/79370/332/7157/8626/604/7161/7159/10397 9 Human_SARS_coronavirus R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 9/2473 14/10654 0.0012128379694872717 0.0027595583650688836 0.0011941007502676464 4893/5921/5753/1398/387/3845/3265/5829/5879 9 Human_SARS_coronavirus R-HSA-3928663 EPHA-mediated growth cone collapse 15/2473 30/10654 0.0012200129593812005 0.002766707074828111 0.0011971941002018218 4627/10627/10398/6714/4637/4067/2044/2534/9475/4628/7525/6093/103910/387/1969 15 Human_SARS_coronavirus R-HSA-525793 Myogenesis 15/2473 30/10654 0.0012200129593812005 0.002766707074828111 0.0011971941002018218 25/1499/6929/6938/4209/4205/1432/4208/1000/998/4654/5600/6300/1013/5608 15 Human_SARS_coronavirus R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 22/2473 51/10654 0.0012559157475093168 0.0028434264118527767 0.0012303916650951098 5321/1783/10382/347688/830/7277/10381/23299/1780/5048/1781/8655/1639/832/636/10376/51143/10383/5049/140735/829/1778 22 Human_SARS_coronavirus R-HSA-69052 Switching of origins to a post-replicative state 34/2473 90/10654 0.0012985212054453276 0.0029350429882553366 0.0012700354805708224 8454/5718/1017/5682/7321/5707/8697/5717/6500/4173/5705/8881/7316/10213/9978/890/84515/5714/4171/51433/5701/6502/81620/5702/8900/29945/10393/6233/51434/7311/29882/4176/7314/996 34 Human_SARS_coronavirus R-HSA-76046 RNA Polymerase III Transcription Initiation 17/2473 36/10654 0.001325645668802845 0.002991424107890631 0.001294432405132972 55718/5434/5440/2971/5451/9330/5441/5435/55703/9328/5437/7702/6908/661/6619/6618/11128 17 Human_SARS_coronavirus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 30/2473 77/10654 0.00138578474419044 0.003121997814498003 0.001350933533356509 5718/5682/51512/5707/63943/10382/347688/5717/7277/9133/10381/5705/7316/10213/891/983/1026/5714/5701/3320/22919/10376/5702/7157/6233/3326/7311/10383/5347/7314 30 Human_SARS_coronavirus R-HSA-983169 Class I MHC mediated antigen processing & presentation 111/2473 371/10654 0.0014554580612364373 0.0032735876393711343 0.0014165286394087159 8454/57154/1147/5718/197131/8945/8065/10952/5682/84708/51320/54850/7321/5707/991/10273/65264/9021/10484/8697/26235/10802/9817/9039/223082/5717/821/6500/6478/81559/5705/26259/7099/4615/79876/64750/6477/8881/8452/7323/10517/54778/7316/10213/9978/23304/7317/22872/4008/11059/55236/567/4734/5714/3693/27252/51444/7704/8651/51433/25831/64219/23327/9867/5701/10134/26270/63893/6502/3309/114609/55294/2923/9632/5702/8453/83737/695/63891/10075/29945/10393/8924/51191/6233/51434/3685/25793/7311/9871/6047/54461/868/9320/29882/57520/6396/7097/4591/3551/26268/7332/3105/997/51676/51132/10427/9820/7314/996/1514 111 Human_SARS_coronavirus R-HSA-381119 Unfolded Protein Response (UPR) 35/2473 94/10654 0.0014935241721856704 0.0033537073064463826 0.0014511975762127975 440/10488/6464/1965/2673/4802/7184/116138/5526/118/1051/1649/3576/468/22872/4800/1639/55738/3068/1054/30827/8894/3309/9451/6347/2931/467/27230/64061/10106/56915/8570/9820/1968/7709 35 Human_SARS_coronavirus R-HSA-70326 Glucose metabolism 34/2473 91/10654 0.0016183731047713114 0.003628117483245489 0.0015699388219659782 4928/5903/2597/5315/5567/2203/5568/348995/79023/57122/23636/5528/5230/3098/23279/4927/79902/5566/5519/5106/226/23225/8604/8086/9972/5518/8021/6396/230/55746/10007/8480/5515/5516 34 Human_SARS_coronavirus R-HSA-400685 Sema4D in semaphorin signaling 13/2473 25/10654 0.00162898483722548 0.0036340930027209083 0.0015725245155244687 4627/389/10627/2064/10398/4233/4637/9475/4628/6093/103910/387/5879 13 Human_SARS_coronavirus R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 13/2473 25/10654 0.00162898483722548 0.0036340930027209083 0.0015725245155244687 6118/7515/7316/5425/5111/6119/6233/7311/3980/6117/10714/5424/7314 13 Human_SARS_coronavirus R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 13/2473 25/10654 0.00162898483722548 0.0036340930027209083 0.0015725245155244687 10484/10802/821/22872/567/10134/3309/2923/9632/9871/6396/3105/10427 13 Human_SARS_coronavirus R-HSA-170968 Frs2-mediated activation 8/2473 12/10654 0.0016534496116871564 0.0036471589505382295 0.0015781783398063232 5604/5594/673/5605/4914/4803/7529/5595 8 Human_SARS_coronavirus R-HSA-264870 Caspase-mediated cleavage of cytoskeletal proteins 8/2473 12/10654 0.0016534496116871564 0.0036471589505382295 0.0015781783398063232 118/841/5339/836/4137/6709/840/7431 8 Human_SARS_coronavirus R-HSA-430116 GP1b-IX-V activation signalling 8/2473 12/10654 0.0016534496116871564 0.0036471589505382295 0.0015781783398063232 5295/2316/1277/7534/6714/5894/7450/1278 8 Human_SARS_coronavirus R-HSA-4641265 Repression of WNT target genes 8/2473 12/10654 0.0016534496116871564 0.0036471589505382295 0.0015781783398063232 51176/1487/83439/6934/3065/7088/1488/6932 8 Human_SARS_coronavirus R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 8/2473 12/10654 0.0016534496116871564 0.0036471589505382295 0.0015781783398063232 23368/355/8797/7157/8626/7161/7159/8795 8 Human_SARS_coronavirus R-HSA-8866907 Activation of the TFAP2 (AP-2) family of transcription factors 8/2473 12/10654 0.0016534496116871564 0.0036471589505382295 0.0015781783398063232 7020/4435/7021/51741/10370/1387/2033/8089 8 Human_SARS_coronavirus R-HSA-9634600 Regulation of glycolysis by fructose 2,6-bisphosphate metabolism 8/2473 12/10654 0.0016534496116871564 0.0036471589505382295 0.0015781783398063232 5567/5568/5528/5566/5519/5518/5515/5516 8 Human_SARS_coronavirus R-HSA-5617472 Activation of anterior HOX genes in hindbrain development during early embryogenesis 43/2473 122/10654 0.00166996289416294 0.0036717773890890286 0.0015888310936368053 9070/3725/5434/5440/8841/11091/79447/2146/5430/84962/8085/5436/5929/5931/5915/5441/3213/5438/5431/7403/5435/5433/9611/9935/10664/5928/5087/22976/1387/5437/2033/23512/5439/6256/58508/23054/9063/8726/5080/8202/5432/1959/7528 43 Human_SARS_coronavirus R-HSA-5619507 Activation of HOX genes during differentiation 43/2473 122/10654 0.00166996289416294 0.0036717773890890286 0.0015888310936368053 9070/3725/5434/5440/8841/11091/79447/2146/5430/84962/8085/5436/5929/5931/5915/5441/3213/5438/5431/7403/5435/5433/9611/9935/10664/5928/5087/22976/1387/5437/2033/23512/5439/6256/58508/23054/9063/8726/5080/8202/5432/1959/7528 43 Human_SARS_coronavirus R-HSA-164378 PKA activation in glucagon signalling 10/2473 17/10654 0.0016882254215404974 0.0036941710978525715 0.0015985211747651148 5575/5567/5568/112/5573/2778/111/5566/5576/5577 10 Human_SARS_coronavirus R-HSA-6788467 IL-6-type cytokine receptor ligand interactions 10/2473 17/10654 0.0016882254215404974 0.0036941710978525715 0.0015985211747651148 3589/3976/3717/3716/1270/5008/3977/7297/1489/3572 10 Human_SARS_coronavirus R-HSA-9022699 MECP2 regulates neuronal receptors and channels 10/2473 17/10654 0.0016882254215404974 0.0036941710978525715 0.0015985211747651148 5770/2904/4233/5775/4988/2903/3066/3065/1385/25942 10 Human_SARS_coronavirus R-HSA-76071 RNA Polymerase III Transcription Initiation From Type 3 Promoter 14/2473 28/10654 0.001769610978389671 0.0038660927744436765 0.0016729141666305305 55718/5434/5440/5451/5441/5435/55703/5437/7702/6908/661/6619/6618/11128 14 Human_SARS_coronavirus R-HSA-69239 Synthesis of DNA 42/2473 119/10654 0.001823025204526682 0.003976455613053431 0.001720669760443559 8454/5718/1017/6118/5682/7321/5707/8697/5717/6500/4173/5705/8881/7316/10213/9978/890/5425/84515/5714/5111/4171/51433/6119/5701/6502/81620/5702/8900/29945/10393/6233/51434/7311/23649/6117/29882/10714/5424/4176/7314/996 42 Human_SARS_coronavirus R-HSA-165159 mTOR signalling 18/2473 40/10654 0.0019171072296554372 0.004175033522360729 0.001806597289098858 6194/207/84335/7249/6198/29904/64223/5571/6794/5494/208/10542/1975/2475/5562/92335/57521/7529 18 Human_SARS_coronavirus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 28/2473 72/10654 0.00203618986144917 0.004427341505401365 0.001915774596475656 5718/5682/7321/5707/991/8697/9212/5717/5705/8881/7316/10213/6790/5714/51433/5701/6502/5702/29945/10393/9232/6233/51434/7311/5347/29882/7314/996 28 Human_SARS_coronavirus R-HSA-622312 Inflammasomes 11/2473 20/10654 0.0020764560686466157 0.004507749566745501 0.0019505683256440564 834/596/351/4790/7295/5970/22861/598/10628/3326/4791 11 Human_SARS_coronavirus R-HSA-5610787 Hedgehog 'off' state 40/2473 113/10654 0.002172387302111338 0.0047085551003108305 0.002037459779480826 8454/5718/8945/2735/5682/5575/54903/5707/5567/1452/10382/5568/5717/6500/112/7277/10381/5705/5573/7316/10213/9978/2778/5727/8650/111/5714/5566/2932/5701/5576/10376/5702/83737/5577/6233/374654/7311/10383/7314 40 Human_SARS_coronavirus R-HSA-69306 DNA Replication 44/2473 127/10654 0.0021848051855701423 0.004728001127132863 0.002045874356070995 8454/5718/1017/6118/5682/7321/5707/8317/8697/5717/6500/4173/5705/8881/7316/10213/9978/890/5425/84515/5714/5111/4171/51433/6119/5701/10926/6502/81620/5702/8900/29945/10393/6233/51434/7311/23649/6117/29882/10714/5424/4176/7314/996 44 Human_SARS_coronavirus R-HSA-174437 Removal of the Flap Intermediate from the C-strand 7/2473 10/10654 0.0022007944454817932 0.004740172651806939 0.0020511411505440493 6118/5425/5111/6119/6117/10714/5424 7 Human_SARS_coronavirus R-HSA-2465910 MASTL Facilitates Mitotic Progression 7/2473 10/10654 0.0022007944454817932 0.004740172651806939 0.0020511411505440493 891/983/5519/5518/55844/5515/5516 7 Human_SARS_coronavirus R-HSA-2470946 Cohesin Loading onto Chromatin 7/2473 10/10654 0.0022007944454817932 0.004740172651806939 0.0020511411505440493 10274/23244/10735/23047/5885/8243/9126 7 Human_SARS_coronavirus_2 R-HSA-381753 Olfactory Signaling Pathway 376/7348 393/10654 1.1518812551443153e-41 1.628760094774062e-38 7.008288057614888e-39 4994/143502/441639/219956/390882/390078/282775/8390/138883/347169/138799/79346/26707/80346/338675/7932/390431/390265/403253/390058/119694/56656/26333/79501/391109/219954/219873/219417/387748/119678/219477/119687/401666/219482/391196/126541/126370/119764/343169/221035/401427/127623/79541/120796/138802/135924/391192/390167/51308/26212/219983/390059/219447/392391/401994/81050/2774/128368/26529/127066/219865/130075/390892/391107/2782/26211/441308/219453/390113/26737/403282/219960/283111/26531/138803/390321/338662/219982/120586/390054/390191/390195/81341/83597/79544/390429/401665/119682/254783/26188/390326/390439/219958/219858/283160/8386/286362/26735/10798/391191/26496/441608/403274/390066/390036/8383/441911/219965/125962/81470/341276/343563/343171/390079/390063/81472/121364/196335/390271/79470/26595/162998/441669/121275/442184/403277/390260/121130/390037/392309/81127/122748/2792/401992/26339/127068/284383/81061/283159/150681/343172/347468/391195/282763/390162/79334/128367/79295/442361/8387/390157/219437/219469/390433/390648/343173/219473/26341/391194/390649/390168/391189/341416/403244/81466/138804/341152/81328/219981/127064/401993/254973/26740/441933/219431/81309/390437/390155/120776/127069/285093/347168/341418/128372/282770/391211/81327/81392/127074/23538/8590/120065/120775/442194/81168/391114/26338/390181/285659/144125/392390/4991/284433/393046/390275/442191/284532/81448/219875/26659/390152/8388/81282/119749/346525/390077/26219/340980/391190/219487/119679/254786/219968/338751/392392/81697/143503/121129/26664/132112/392376/390038/26716/346517/286365/26246/119774/390148/26189/79317/390883/403273/283092/338755/26539/81696/4995/256144/127077/403278/120793/125958/219428/79339/26533/390081/4992/81285/26493/391112/219874/158131/26494/138805/26693/442186/284521/219869/120066/81442/341568/344892/81099/390445/79324/219436/390067/79310/26696/390201/219484/81797/135941/26476/26689/144124/219429/26692/124538/119765/26245/8392/219464/79345/390142/254879/7905/390144/390151/219479/135946/390083/79290/403239/81300/390442/390190/390154/134083/283093/390072/283365/26248/219957/390261/127059/122742/390061/403284/283189/65055/341799/119772/390327/64108/26682/390264/402135/81469/26538/92840/390323/390084/219432/128366/4993/219493/283297/256148/79473/338674/26658/401667/127062/26648/389090/390197/283162/390199/343406/26532/138881/125963/219959/128371/122740/390093/390075/138882/390064/135948/119692/128360/119695/255725/81318/219952/219986/127385/392138/120787/441670/219438/390174/219870/390436 376 Human_SARS_coronavirus_2 R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 302/7348 309/10654 4.659154645849765e-40 3.294022334615784e-37 1.4173638870006128e-37 8454/5689/127544/11065/221687/9666/84937/55070/5682/55819/93611/8916/7321/51665/65264/122769/9021/8697/26235/9817/9039/154881/7174/6478/143471/5705/57674/9690/8452/5709/9978/5695/23304/55236/54620/4734/7337/84676/7704/3093/10489/5711/23327/51465/10616/5683/89910/25898/5699/7328/7428/5702/22954/401036/83737/51529/140461/10075/29945/79176/8924/90135/56658/51434/6468/10425/25793/23295/51666/90293/54461/29882/7334/92591/55182/84961/4591/7332/5696/5691/9820/55658/7314/996/10324/283807/9354/5718/197131/8945/51088/64410/146330/51320/5700/122706/5707/10477/148581/92912/23198/10533/140462/51130/6477/7323/10517/9604/64718/4008/84861/11059/84085/27252/51444/26118/51433/9861/26249/55905/143279/6502/5698/27246/5692/5713/9903/201456/26190/79654/5710/9040/7324/5719/64682/8925/51191/6233/26091/6047/131405/868/136371/127247/5930/11275/29116/26268/115290/51725/140459/23608/55585/64320/51132/899/23352/26224/10293/114088/285231/142678/246184/142686/387522/151636/11146/255488/9616/91694/10193/140739/150726/390594/81559/144699/5706/200845/79876/26263/8881/7326/6049/57630/89890/22888/7317/80196/140456/55958/84078/5714/26272/8651/64219/140458/5688/55336/5687/26270/63893/89122/118424/5708/55008/10422/84727/90933/63891/9246/10393/5704/9870/9520/4012/25847/7327/51343/7311/7318/55175/9320/26232/57520/5694/92369/997/84261/7325/140691/57154/140460/5684/79754/6737/8065/5720/57531/84708/54850/7319/79791/26046/991/84231/10273/7320/5690/223082/5717/25897/9491/6500/26259/10197/53339/154214/7336/64750/51619/23376/54778/142689/7316/10213/114907/54926/7335/222235/25831/7322/5715/9867/5701/23291/5685/5686/55521/55294/135892/8453/80176/8139/126433/26267/142685/5716/90025/7064/84541/23194/55284/80204/26234/27338/23014/90678/5693/5721/51676/57542/642 302 Human_SARS_coronavirus_2 R-HSA-983169 Class I MHC mediated antigen processing & presentation 354/7348 371/10654 2.075604295761729e-38 9.783014914023615e-36 4.209471168246594e-36 8454/8773/5689/127544/11065/221687/9666/84937/55070/5682/55819/93611/8916/3107/7321/51665/65264/122769/9021/10484/8697/26235/9817/55176/9039/154881/7174/6478/811/143471/5705/57674/10333/9690/8452/5709/9978/5695/23304/567/55236/54620/4734/7337/3693/84676/7704/3106/3093/10489/5711/23327/51465/51752/10616/5683/929/3309/89910/25898/5699/7328/9632/7428/5702/22954/401036/83737/51529/140461/10075/29945/79176/8924/90135/56658/51434/6468/10425/25793/23295/51666/90293/54461/29882/7334/92591/55182/84961/4591/3551/7332/5696/5691/9820/55658/7314/996/10324/283807/9354/5718/197131/8945/51088/64410/10952/146330/51320/5700/122706/5707/10477/148581/92912/23198/10533/140462/6892/51130/8517/6810/6477/7323/10517/9604/1515/22872/64718/4008/7096/84861/11059/84085/27252/51444/26118/51433/9861/26249/55905/10134/143279/6502/5698/27246/5692/5713/9903/201456/26190/79654/5710/9040/7324/5719/64682/8925/51191/6233/3685/26091/6047/51128/131405/868/136371/6396/127247/1535/5930/11275/29116/26268/115290/51725/140459/23608/55585/64320/51132/1514/899/23352/26224/4688/10293/114088/285231/653361/142678/246184/142686/387522/151636/11146/255488/9616/91694/10802/10193/6890/140739/821/150726/390594/81559/144699/5706/200845/79876/26263/9554/8881/7326/6049/57630/89890/22888/29927/7317/80196/140456/55958/84078/50489/5714/26272/8651/64219/140458/5688/55336/5687/26270/63893/89122/118424/5708/55008/2923/10422/84727/695/90933/63891/9246/10393/5704/9870/9520/4012/25847/7327/51343/7311/9871/7318/55175/9320/26232/57520/5694/8673/92369/3105/997/84261/7325/140691/23643/57154/1147/140460/5684/79754/6737/8065/5720/57531/84708/54850/7319/79791/26046/991/84231/10273/7320/5690/223082/5717/25897/9491/6500/26259/10197/7099/53339/154214/7336/4615/64750/51619/23480/23376/6891/54778/142689/7316/10213/114907/54926/7335/222235/25831/7322/5715/9867/5701/9341/23291/5685/5686/55521/55294/135892/8453/80176/8139/126433/26267/948/142685/1520/5716/90025/7064/84541/23194/55284/80204/26234/27338/7097/23014/1536/90678/5693/5721/51676/10427/57542/642 354 Human_SARS_coronavirus_2 R-HSA-5663205 Infectious disease 361/7348 383/10654 1.6966434939092195e-35 5.9976347509690905e-33 2.580684051261918e-33 3839/6804/6158/6884/23165/6875/5689/51652/6138/2237/6227/7852/6206/6234/6191/162/6128/5682/6132/6129/4057/27243/6874/6176/1174/811/6224/6146/348995/6154/143471/6202/57122/5705/55048/3981/6169/5431/23511/5435/5709/6175/9978/5433/6218/5695/2960/292/567/51271/6173/23279/5605/6167/5711/23327/116832/29082/8732/23225/5683/2965/6192/2534/6156/27183/5699/6143/5439/5702/6456/6873/3836/6139/30011/2885/163/9972/6881/2967/51616/3921/8021/7040/1794/11198/904/55690/51497/5062/55746/6208/5696/6170/5691/92421/7296/7314/5879/5718/137492/3303/8945/6203/51606/1839/161/402569/5606/6147/25978/5700/51160/122706/5707/2959/8027/10053/6222/2060/7518/8106/23198/404672/84168/9636/10015/91782/5438/6134/3978/10762/79720/6155/1500/51534/9397/6714/6231/9861/79902/6142/11168/9883/23521/89853/83860/51510/999/5698/9146/6455/5692/5713/5710/2068/5902/6207/5478/5719/6233/6844/7514/1025/140032/3932/1213/5610/1211/6188/6396/129401/6883/7936/1175/6829/801/5608/8907/200916/6122/2957/940/805/25920/6230/60489/928/1173/4928/2963/3838/5434/5903/6857/6194/55706/7175/79643/6166/1938/5436/6136/6878/3841/6125/4869/821/5706/6232/160/6160/6616/293/5611/920/4233/4331/5714/6193/4927/6210/6229/8148/6205/2966/2962/10898/3840/5688/54457/8812/5687/5708/128866/140801/6235/905/6181/2071/5901/8086/5704/3326/7311/6223/25873/93343/6880/6908/7251/8905/5694/3304/1104/2547/9045/6882/2961/6187/6416/5432/6168/22916/155382/1234/6157/6137/6877/5905/6144/3837/6917/81929/5440/164/5684/9349/8065/4736/2926/5720/902/51121/9631/5604/1499/3159/6159/6217/3843/5430/6152/5690/5045/7520/5717/9491/6500/127833/6749/51065/6141/79023/6123/5441/23636/10197/7469/919/130340/6164/4686/7316/10213/6872/53371/3055/6209/9688/11224/6165/8731/6130/6879/9150/5715/9525/6204/5701/2958/867/6228/5437/5685/3320/8815/5686/9900/6124/6827/5609/2968/5716/9844/6189/808/6135/6201/375/6161/138474/1022/5693/10254/5721/6457/8178/8480/6133/291 361 Human_SARS_coronavirus_2 R-HSA-6798695 Neutrophil degranulation 437/7348 480/10654 2.0124217888309117e-32 5.691128818813818e-30 2.4487995661984572e-30 5869/8773/7130/9798/1727/5689/8804/5777/8514/5806/4893/9218/4790/3240/960/1823/1511/5657/57826/1915/4057/3107/10875/203068/9761/5175/5199/383/654364/84766/8836/2268/5211/5908/1460/1265/29108/23385/10394/54509/6280/5788/535/10577/5912/10312/5709/5269/10576/1509/5695/2896/4126/10562/8655/567/290/7133/154664/3106/3074/3417/3043/388698/1667/2548/2204/1432/11010/3920/5476/8904/5683/929/201294/158747/2588/3482/4311/80142/2444/23200/5702/566/9961/51552/10075/56729/10487/6947/6709/684/6093/160364/441864/8826/9522/1794/4282/3608/2720/3312/387263/2665/126014/51719/4758/1654/967/2519/6037/5879/51316/2717/5718/1992/3303/58485/2934/80331/57554/6518/64333/56954/161/1084/56888/3579/94103/5707/2358/3848/8972/272/823/427/353189/5594/4831/4680/5787/6727/127829/7414/258010/10533/55754/4257/51209/326624/847/3683/2517/25852/3934/22918/8895/5834/9545/1315/102/116844/1774/84443/4069/5317/4973/9861/5870/410/6556/411/28988/226/2821/5553/199675/978/55832/968/8560/23601/5713/1/2495/3728/3614/10043/4125/5478/5719/374395/5328/728/11001/5580/23191/3685/302/634/1729/11026/9145/5236/25797/6036/1535/64114/2040/230/23250/2990/401258/5663/7879/8907/671/1508/28956/30/10450/7077/25801/1828/3903/23352/23412/7276/5284/83858/4332/10159/1938/8635/51125/51646/1650/338339/3684/79888/387921/3163/64386/54472/101/3577/26/79169/2215/55860/10549/2760/5864/4318/3958/963/79980/23317/5836/53917/6993/11240/10321/6616/5329/966/5611/84061/1116/527/3101/6279/6515/54918/11322/4048/353/5337/10092/170482/5795/6793/197/8694/140885/2171/3310/2352/1832/5708/55313/3615/11314/138050/23218/820/51143/4860/6386/8993/8778/5473/3326/10857/55004/10097/57153/3916/53831/240/10383/387/81619/178/10396/196527/683/5049/4317/51806/80184/1476/3304/84329/2547/8673/10493/1075/53916/6282/114790/22931/1778/10694/2512/3837/10890/5036/8621/5005/29099/327/84514/5315/8876/6590/23197/1991/10120/6317/7520/5717/2919/5004/1118/221/9725/1604/25840/1512/2357/10213/4718/6278/121260/5547/5023/5799/932/1522/2799/5768/1471/9588/29952/7415/3146/79792/4353/5701/6836/9342/8649/5265/3320/5686/388697/23593/391/1669/175/25798/5873/1088/57126/10555/150372/26578/1143/23071/51411/5878/2683/8566/11031/5646/948/1520/945/1675/7226/719/93100/47/79895/5906/89777/100049587/81567/10855/3687/353376/124583/84418/7097/5660/1536/8987/10970/3689/961/2207/5724/51382/2950/718/5223 437 Human_SARS_coronavirus_2 R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 238/7348 244/10654 3.5127397667284595e-31 8.278356716923402e-29 3.562041377489561e-29 8449/23165/6633/8683/6431/84271/55696/4904/51639/51585/9128/199746/23450/348995/57122/5431/9092/23511/81608/5435/6625/5433/51645/3190/1477/9416/65109/56339/22826/23279/8233/728343/22938/988/23020/23225/6631/3181/5439/1660/9410/6638/57721/9877/9972/8021/3312/10907/10291/55746/26121/10262/7919/53981/6432/10084/8563/6430/51340/56001/6627/6936/83443/11051/80145/9129/9879/10081/8106/51690/27238/55749/5438/85313/10762/54883/22794/9785/11338/1655/9343/29107/3185/4116/6626/11157/285755/1478/24144/79902/9883/51213/10236/10250/4670/26097/8926/51362/10465/55660/25949/23283/2521/1977/3191/10285/6636/23524/10914/57187/6396/129401/79228/8175/2733/84950/3188/84324/56259/5725/1994/10450/7536/4928/2963/6635/5434/5903/220988/6632/10283/55706/7175/24148/154007/7884/23350/5436/10523/6428/27258/10212/6637/55110/5093/55954/84321/6429/57819/4927/10181/2962/10898/10569/23658/6434/9295/84844/10482/51692/10421/11193/8086/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/81929/5440/55599/51691/10946/9631/27339/5430/79869/85437/11325/57703/3184/25804/29894/9589/11017/51503/3178/79023/5441/23636/3183/79622/10594/4686/8189/23398/10713/53371/10978/5546/7307/10772/9688/9984/5437/6629/10189/10949/51729/11066/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/84248/6427/5356/57461/84991/8480/10992/55339/6628 238 Human_SARS_coronavirus_2 R-HSA-500792 GPCR ligand binding 424/7348 468/10654 3.0696727420165236e-30 6.200738938873377e-28 2.6680764584745128e-28 2788/729230/4160/10316/2149/23620/1880/3972/1816/7852/7478/2692/10161/50833/83551/3363/5726/338442/155/2740/64805/1237/5734/11211/2550/50832/3354/2841/2696/4987/51289/3360/117/259294/2150/3060/2912/3576/6360/2798/5737/338557/4985/2920/3061/2921/1236/259295/799/6010/9568/554/2911/2840/2831/5367/3549/5028/5741/4988/6370/58191/153/6755/6866/1524/1081/94233/643/5029/2782/2867/4161/185/339403/2914/8843/64106/2847/10267/2833/6347/9290/9170/6469/187/221391/6750/259296/259289/50835/2587/53829/8111/2787/6387/6368/4544/4543/2922/10663/4889/2535/9283/727/122042/7476/1909/5732/338398/117579/133/3579/6375/2492/23566/2358/2916/319100/7473/259293/1131/8322/6846/5179/27334/10681/27202/5021/6865/6367/7471/2797/8811/1812/56923/2832/2693/27199/2826/5727/6376/165140/27198/7201/89780/5443/7477/8323/3627/2792/54429/50846/3361/6346/7475/553/151306/134864/257313/134/8321/59350/3814/10800/5744/2863/7481/1129/51083/2785/2783/2784/2829/1233/7482/222545/6366/1241/2861/728/7474/183/10022/170589/7479/6373/57121/4922/5731/2865/7855/1132/1814/80835/3362/6357/552/4159/2925/8698/9934/2151/6869/50840/2791/10268/6343/23596/2147/1813/50865/7976/7480/10886/2837/80326/10803/146/2913/9340/116/3357/57486/351/11251/8477/84432/3352/8484/2828/3062/1907/6344/148/6351/4158/6863/6752/135/1903/84539/6753/3577/594857/4157/2918/5368/6754/6915/8862/10911/301/5032/2642/56670/150/2853/29933/6751/5020/4935/887/4829/186/53637/60675/10563/5540/2864/1901/5733/256933/7200/7252/5729/10850/79924/624/2641/1392/2796/4852/9287/7483/4828/134860/2786/680/5995/50838/5473/4283/1910/6870/128674/11255/885/122876/113091/10874/83756/84634/147/6356/611/56477/51384/387129/259286/3350/129521/1234/10692/151/57007/3356/84109/7432/7472/9294/54331/4923/1128/283869/59345/4986/6608/6374/2488/5539/259287/136/2852/50836/1230/846/3358/4886/2919/7433/10266/7484/5745/1908/51764/94235/2695/259290/5196/3827/5746/1604/5173/2357/796/55970/2778/6352/57105/1133/140/54361/3269/6348/886/9038/2862/152/2691/1906/6364/7253/80834/259292/5031/8620/2793/5030/5697/3640/56413/3355/3351/6288/6372/797/5739/50834/259285/3973/7434/10203/719/6363/2917/1268/50831/3375/2359/1395/50839/347148/2846/5660/1815/1325/1232/4295/1902/551/154/50837/9002/1269/2915/3274/59340/5724/4887/1394/2790/718/623 424 Human_SARS_coronavirus_2 R-HSA-8951664 Neddylation 227/7348 234/10654 1.88170133561873e-28 3.3259071107061056e-26 1.431083384194245e-26 8454/5689/56995/5682/64344/80344/80067/93611/55884/7321/51665/122769/9021/4738/26235/9817/9039/154881/5929/3091/143471/5705/140825/8452/5709/9978/5695/54620/7704/10980/10489/5711/7347/5683/5699/79269/10987/7428/5702/401036/140461/79176/90135/6468/26094/25793/1154/51666/90293/54461/92591/84961/5696/5691/9820/7314/51514/10324/283807/5718/51397/54165/8945/51088/64410/23363/23038/146330/5700/122706/5707/23198/140462/55827/51130/28991/332/7323/9306/10517/50717/4008/84861/84085/79016/27252/1643/26118/9861/122416/26249/23369/6502/90864/55832/5698/5692/10920/5713/9903/201456/26190/10238/5710/9040/5719/10116/6233/83987/136371/8835/127247/11275/54939/26268/115290/54951/51725/140459/55208/10537/8451/899/26224/23412/9655/149951/285231/142686/9616/140739/5931/150726/390594/144699/5706/200845/26263/8450/89890/140456/55958/84078/5714/55527/26272/140458/5688/55336/5687/26270/1161/5708/1642/84727/5704/2873/7311/2034/55175/8533/26232/5694/51122/92369/84261/150684/51138/56929/9318/140460/5684/79754/8065/5720/29099/11091/25879/54850/79791/5690/5717/9491/6500/28952/26259/10197/53339/142689/7316/10213/114907/64708/222235/54876/7322/5715/5701/23291/170622/5685/5686/55294/8453/123879/80176/8139/23142/126433/26043/123228/26267/142685/5716/84541/23194/80204/26234/8883/23014/8816/5693/5721/84259/51676/50813/57542 227 Human_SARS_coronavirus_2 R-HSA-72172 mRNA Splicing 187/7348 191/10654 1.7906199587060046e-25 2.813262912900323e-23 1.2105009779322465e-23 8449/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/5431/9092/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/8233/22938/988/23020/6631/3181/5439/1660/9410/6638/3312/10907/10291/26121/10262/53981/6432/10084/6430/51340/6627/6936/83443/11051/9129/9879/10081/8106/51690/27238/55749/5438/85313/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/10236/10250/4670/8926/51362/10465/55660/25949/23283/2521/3191/10285/6636/23524/10914/8175/84950/3188/56259/5725/1994/10450/7536/2963/6635/5434/220988/6632/10283/24148/154007/23350/5436/10523/6428/27258/6637/55110/5093/55954/6429/57819/10181/2962/10898/10569/23658/6434/9295/84844/51692/10421/11193/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/55599/51691/10946/27339/5430/79869/85437/11325/57703/3184/25804/29894/11017/51503/3178/5441/3183/79622/10594/4686/8189/23398/10713/10978/5546/7307/10772/5437/6629/10189/10949/51729/11066/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/57461/84991/10992/55339/6628 187 Human_SARS_coronavirus_2 R-HSA-5663202 Diseases of signal transduction 342/7348 377/10654 8.587037772080057e-25 1.2142071409721201e-22 5.2245345602760766e-23 5295/8454/2308/5689/374/4893/11052/2250/5335/71/79718/5682/5291/892/5526/817/1452/7039/9530/613/9372/182/5908/3082/941/55109/143471/23385/2064/5705/54845/5431/6776/5435/5709/9978/5433/5695/8546/9759/9612/22866/5605/4609/4089/22938/5037/3549/5711/1387/3717/10827/4088/2244/6907/5683/145957/324/2534/3690/408/9965/5699/6400/8312/11064/5439/2264/5702/4296/5894/9794/9542/2885/2475/8660/79412/51009/8826/9846/5518/57534/2252/6469/1185/4140/7040/2253/3845/3265/80351/4763/5696/7750/5691/28514/7314/5879/5515/5718/818/5947/8805/1839/26127/5290/3667/6801/8823/79885/2065/2648/9734/55869/55750/5700/3815/122706/5707/10956/8844/51564/7094/8322/55534/5594/3280/2069/84335/8074/7249/23198/84441/7414/10533/10013/23164/2260/5438/5528/83933/3714/89780/102/8323/57085/2249/6714/2099/50846/5664/9861/2248/5519/9061/8850/399687/2932/7046/2247/5698/5880/10000/5692/5713/2335/1445/5710/3066/2280/5719/6233/2266/7409/2246/27248/2251/5154/3932/2931/2243/7855/369/801/5781/5663/940/1523/57670/253260/805/5170/2963/5434/7276/6464/22943/142678/572/283455/3674/5436/409/5706/6199/10046/9208/84447/673/8315/6774/2263/4233/8658/1024/5714/6772/6934/64223/10014/2962/8503/5688/5159/5687/29851/5708/3084/9148/5529/816/4087/208/9365/6654/5704/10718/79109/56829/7048/7311/5293/7450/1956/11160/60/9444/2549/51107/611/5694/4851/5432/22916/11140/7529/5595/5516/4000/1147/8822/27044/815/5440/5684/22906/8841/685/5720/8087/1487/2309/5604/1499/10018/5525/10142/842/139285/5430/23462/207/5690/5717/27121/1027/9491/6500/8817/5441/10197/54518/2100/2254/4686/7316/10213/152831/1950/9611/54492/1026/26281/10818/7415/5715/80853/10256/2261/5701/867/5437/5685/2255/3164/3320/5686/2033/54894/391/55294/5728/3065/2066/27006/5527/1488/5716/1385/5906/5155/54567/4254/5296/808/3516/9715/5693/5721/5245/5156/4193 342 Human_SARS_coronavirus_2 R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic 196/7348 202/10654 9.775341006331325e-25 1.2565756529956812e-22 5.406839331731585e-23 6811/400/11014/64837/60592/11311/8674/11127/51807/53407/347688/3798/5861/10381/7278/1780/5048/9570/8655/84516/832/285643/55738/10112/636/64147/7846/2590/3482/51226/9382/81027/11004/56894/10228/10749/83452/6293/27314/8675/2800/339122/60560/81930/10652/54732/51272/7110/51164/60561/113220/79861/3797/10618/9321/29127/55275/55605/23299/51209/377/10466/23647/8398/9827/1315/22836/347517/3796/5870/79571/124602/11316/55614/89953/56992/91949/8729/4074/23423/10376/2803/1314/10540/9267/3835/147700/3833/8677/10139/378/9493/26286/26958/140735/10959/1523/27128/3831/84364/22820/51542/84617/2589/22796/11258/1783/27333/9265/55850/9585/10382/93661/55860/830/3832/7277/4121/10671/9554/23303/1639/8775/26153/81876/9183/9712/1062/4124/11015/146909/347733/662/90990/10244/51143/9648/23046/10383/24137/84790/54734/84643/10945/5049/90196/57589/51594/22920/7280/829/22931/1778/9609/55582/5321/9371/25839/51014/23095/5050/84316/83548/9950/63908/112714/1781/22930/738/25782/10121/9367/10226/9341/6836/9527/9342/57511/547/51560/8774/143187/10972/381/4905/3834/9276/55083/3799/9266/375/84342/221458/10905/22818/372 196 Human_SARS_coronavirus_2 R-HSA-72163 mRNA Splicing - Major Pathway 179/7348 183/10654 3.1316748248939612e-24 3.690156835333384e-22 1.5878140778848333e-22 8449/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/5431/9092/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/22938/988/23020/6631/3181/5439/1660/9410/6638/3312/10907/10291/26121/10262/53981/6432/10084/6430/51340/6627/6936/83443/11051/9129/9879/8106/51690/27238/55749/5438/85313/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/10236/10250/4670/8926/51362/10465/55660/25949/23283/2521/3191/10285/6636/23524/10914/8175/84950/3188/56259/5725/1994/10450/7536/2963/6635/5434/220988/6632/10283/24148/23350/5436/10523/6428/27258/6637/55110/5093/6429/57819/10181/2962/10898/10569/23658/6434/9295/84844/51692/10421/11193/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/51691/10946/27339/5430/79869/11325/57703/3184/25804/29894/11017/51503/3178/5441/3183/10594/4686/8189/23398/10713/10978/5546/7307/10772/5437/6629/10189/10949/51729/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/57461/84991/10992/55339/6628 179 Human_SARS_coronavirus_2 R-HSA-9006925 Intracellular signaling by second messengers 282/7348 305/10654 5.679808832827323e-24 6.177884376629103e-22 2.6582425144730307e-22 5295/1912/2308/5689/374/3725/6591/3643/2250/5335/5682/23035/5291/1822/1459/5526/9112/817/6045/5578/7039/5582/27327/80012/3082/1460/941/143471/2064/5705/5709/5695/107/1457/1911/4734/3709/11060/5711/5928/10325/5683/145957/2534/23512/9965/57332/5699/2444/2264/3630/5702/192669/1107/8975/3654/5371/9542/2885/8396/2475/8660/5518/1386/10670/2252/4343/2253/80351/64121/5696/5691/7314/5879/5515/5718/818/23396/1839/5290/3667/6801/8823/2065/23186/5700/3815/122706/5707/5567/2146/51564/5594/2069/84335/84232/8074/7249/23198/79837/112/57761/8395/100532731/2260/5573/5528/111/2249/6714/2099/9861/7101/81847/2248/5519/2932/84733/57459/2247/5698/5880/10000/5692/5713/5710/3066/7157/5613/5719/6233/5580/7409/2246/2251/5154/3932/2931/3710/331/117145/8726/196883/8394/115/26523/7874/801/5781/57521/23608/940/6015/253260/28956/805/5170/3838/572/23239/9219/8535/5568/5931/58528/5706/6199/113/2263/4233/8658/5714/10645/1108/2122/64223/5566/10014/8503/5688/5159/5687/29851/5708/3084/54815/6009/5529/816/7189/208/9365/5577/5704/10718/79109/55004/57504/7311/5293/1956/648/2549/5694/23466/53615/109/5595/5516/1147/8822/27161/815/5684/8841/685/5305/5720/2309/5468/5525/5575/842/5978/10273/207/5690/57690/5717/1027/9491/8817/114/3708/10197/108/192670/4615/153129/2100/2254/7316/10213/152831/1950/1026/10768/26281/57167/10818/5715/1958/2261/5701/5576/5685/2255/8649/3164/5686/391/5728/6615/3065/2066/27006/23028/5987/23112/10542/5527/5716/1385/5155/4254/5296/5581/808/5693/5721/5156/4193 282 Human_SARS_coronavirus_2 R-HSA-9607240 FLT3 Signaling 250/7348 267/10654 1.4033661239654354e-23 1.4173997852050898e-21 6.0988392455039235e-22 5295/5689/374/2674/4893/6711/2250/1437/71/5682/1844/5291/1850/1848/5526/817/84292/7039/5908/3082/143471/2064/5705/8452/6776/4684/5709/9978/5695/1852/2668/22866/5605/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/3563/1741/9542/2885/6709/8660/8826/9846/5518/2252/4140/2253/3845/5623/3265/4763/5696/5691/7314/5515/54106/5923/5718/818/57554/1839/5290/3667/8823/8831/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/57761/5921/4902/2260/5528/2902/3718/2249/25780/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/80824/1445/5710/5719/2906/6233/51332/2266/2246/2251/5154/2243/1843/117145/369/801/200734/5781/30849/8682/4747/11221/28956/805/5170/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/409/5706/1438/673/2676/5140/8315/2263/4233/84078/5714/6710/5688/5159/5687/5708/3084/5529/816/9693/208/9365/6654/5704/10718/3716/7311/7450/1956/60/5536/2549/5694/5924/7529/5595/25759/5516/8822/5786/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10817/10197/54518/2254/7316/10213/152831/1950/3560/5289/3055/57731/26281/10818/5715/8437/10256/2261/5701/5685/2255/8649/53358/5686/2066/6708/27006/5979/1742/5527/5716/88/5906/5155/9048/4254/5296/399473/808/3559/5693/5721/5245/5156/161742/284 250 Human_SARS_coronavirus_2 R-HSA-1257604 PIP3 activates AKT signaling 247/7348 264/10654 3.6139154398559773e-23 3.406717621304235e-21 1.465854824025793e-21 5295/1912/2308/5689/374/3725/6591/3643/2250/5682/23035/5291/1822/1459/5526/9112/6045/7039/27327/80012/3082/1460/941/143471/2064/5705/5709/5695/1457/1911/4734/11060/5711/5928/10325/5683/145957/2534/23512/9965/57332/5699/2444/2264/3630/5702/192669/1107/8975/3654/5371/9542/2885/8396/2475/8660/5518/1386/10670/2252/4343/2253/80351/64121/5696/5691/7314/5879/5515/5718/23396/1839/5290/3667/6801/8823/2065/23186/5700/3815/122706/5707/2146/51564/5594/2069/84335/84232/8074/7249/23198/79837/57761/8395/100532731/2260/5528/2249/6714/2099/9861/7101/81847/2248/5519/2932/84733/57459/2247/5698/5880/10000/5692/5713/5710/3066/7157/5719/6233/7409/2246/2251/5154/3932/2931/331/117145/8726/8394/26523/7874/5781/57521/23608/940/6015/253260/28956/5170/572/23239/9219/8535/5931/58528/5706/6199/2263/4233/8658/5714/1108/2122/64223/10014/8503/5688/5159/5687/29851/5708/3084/54815/6009/5529/7189/208/9365/5704/10718/79109/55004/57504/7311/5293/1956/648/2549/5694/23466/53615/5595/5516/1147/8822/27161/5684/8841/685/5305/5720/2309/5468/5525/842/5978/10273/207/5690/57690/5717/1027/9491/8817/10197/192670/4615/153129/2100/2254/7316/10213/152831/1950/1026/26281/57167/10818/5715/1958/2261/5701/5685/2255/8649/3164/5686/391/5728/6615/3065/2066/27006/23028/5987/23112/10542/5527/5716/1385/5155/4254/5296/5693/5721/5156/4193 247 Human_SARS_coronavirus_2 R-HSA-162906 HIV Infection 220/7348 233/10654 2.823426055467699e-22 2.495202776519579e-20 1.0736449079344277e-20 6884/23165/6875/5689/51652/2237/7852/162/5682/27243/6874/1174/348995/143471/57122/5705/55048/3981/5431/23511/5435/5709/9978/5433/5695/2960/292/567/51271/23279/5711/23327/29082/8732/23225/5683/2965/2534/27183/5699/5439/5702/6873/3836/163/9972/6881/2967/51616/8021/1794/11198/904/55690/51497/5062/55746/5696/5691/92421/7314/5879/5718/137492/8945/51606/161/25978/5700/51160/122706/5707/2959/10053/7518/23198/404672/10015/91782/5438/3978/10762/79720/51534/9397/9861/79902/11168/9883/89853/83860/51510/5698/5692/5713/5710/2068/5902/5478/5719/6233/7514/1025/3932/6396/129401/6883/7936/1175/6829/8907/2957/940/25920/60489/1173/4928/2963/5434/5903/55706/7175/79643/5436/6878/4869/5706/160/293/920/4331/5714/4927/8148/2966/2962/5688/54457/8812/5687/5708/128866/905/2071/5901/8086/5704/7311/93343/6880/6908/7251/8905/5694/1104/2547/6882/2961/5432/22916/155382/1234/6877/5905/3837/6917/81929/5440/164/5684/8065/5720/902/9631/3159/5430/5690/5045/7520/5717/9491/6500/6749/79023/5441/23636/10197/7469/919/130340/4686/7316/10213/6872/53371/3055/9688/8731/6879/9150/5715/9525/5701/2958/5437/5685/8815/5686/6827/2968/5716/9844/375/138474/1022/5693/5721/8178/8480/291 220 Human_SARS_coronavirus_2 R-HSA-373076 Class A/1 (Rhodopsin-like receptors) 304/7348 335/10654 3.353271123754864e-22 2.789132569993751e-20 1.2001180863964776e-20 729230/4160/10316/2149/23620/1880/3972/1816/7852/10161/83551/3363/338442/155/64805/1237/5734/3354/2841/4987/51289/3360/2150/3060/3576/6360/2798/5737/338557/4985/2920/3061/2921/1236/6010/554/2840/2831/5367/5028/4988/6370/58191/153/6755/6866/1524/1081/94233/643/5029/2867/4161/185/339403/8843/64106/2847/2833/6347/9290/9170/187/221391/6750/2587/53829/8111/6387/6368/4544/4543/2922/10663/4889/9283/727/122042/1909/5732/117579/3579/6375/2492/23566/2358/319100/1131/6846/5179/27334/27202/5021/6865/6367/2797/8811/1812/56923/2832/2693/27199/2826/6376/165140/27198/7201/5443/3627/3361/6346/553/151306/134864/257313/134/59350/3814/10800/2863/1129/51083/2829/1233/6366/1241/2861/728/183/10022/170589/6373/57121/4922/5731/2865/1132/1814/3362/6357/552/4159/2925/8698/9934/2151/6869/23596/2147/1813/50865/10886/2837/10803/146/3357/57486/351/11251/8477/84432/3352/8484/2828/3062/1907/148/6351/4158/6863/6752/135/1903/84539/6753/3577/594857/4157/5368/6754/6915/8862/10911/301/5032/56670/150/2853/29933/6751/5020/4935/887/4829/186/53637/60675/10563/5540/2864/1901/5733/256933/7200/7252/5729/10850/624/2796/4852/9287/4828/134860/680/5995/5473/4283/1910/6870/128674/11255/885/122876/10874/84634/147/6356/611/56477/387129/3350/129521/1234/10692/151/57007/3356/84109/9294/4923/1128/283869/4986/6374/2488/5539/136/2852/1230/3358/4886/2919/1908/5196/3827/5173/2357/6352/57105/1133/140/3269/6348/886/9038/2862/152/1906/6364/7253/5031/8620/5030/5697/3640/56413/3355/3351/6288/6372/5739/3973/719/6363/1268/2359/347148/2846/5660/1815/1325/1232/4295/1902/551/154/9002/1269/3274/59340/5724/4887/718/623 304 Human_SARS_coronavirus_2 R-HSA-72766 Translation 268/7348 291/10654 3.887825278589835e-22 3.0541027466255703e-20 1.3141304158040496e-20 6158/6138/5464/6227/6206/1965/6234/27335/6191/6128/6132/1917/84545/6129/1915/64979/26284/80222/9255/6176/55176/8668/27068/51318/6224/6146/6154/8662/26986/6202/64949/65003/6150/10573/64983/55052/6169/6175/219927/6218/6728/64960/6173/64968/11222/6167/116832/51069/118487/28977/6192/6156/6143/1973/124995/28973/51116/6139/6745/51067/64975/64928/3921/116541/128308/51258/8665/10667/65005/84340/23478/6208/51073/6170/92935/65080/64981/6203/51504/51253/10952/29093/6147/8666/54534/6222/60488/64432/4528/8667/51642/6727/7818/6184/79731/6183/58477/2935/6134/6747/6731/55699/6155/55157/10240/6729/6231/6142/7458/8663/23521/23107/8894/65008/1981/85476/6185/6207/64978/1977/6726/6233/28957/219402/9801/140032/51386/51373/6188/26589/10102/1978/64965/9553/7284/200916/6122/1968/6230/8669/6194/2107/122704/6166/124454/1938/1650/1983/6136/6125/1937/23395/10056/6232/6160/6748/51023/29927/1933/60559/6746/6193/6210/6229/6205/54148/28972/51650/57038/64976/140801/23438/6235/79587/51263/6181/740/8893/54948/1975/23471/55168/64951/7311/6223/25873/8664/63875/6730/23708/90701/9045/6187/6168/6157/6137/92259/1974/54460/55037/29074/51264/6144/10352/6182/9349/57505/4736/8891/29088/327/51121/65993/6159/56945/9521/6217/1936/54516/6152/57129/92399/79590/51065/6141/10480/116540/6123/28998/1967/23480/25973/6164/63931/8661/57176/64963/9669/6209/1964/11224/6165/10884/6130/8890/6204/64969/51081/6228/54938/7965/5018/78988/55173/6124/90480/2193/3646/6189/9789/6135/6201/6161/51649/54998/8892/6133/51021 268 Human_SARS_coronavirus_2 R-HSA-5684996 MAPK1/MAPK3 signaling 238/7348 255/10654 6.071735089648723e-22 4.3308846932146895e-20 1.863508786330746e-20 5689/374/2674/4893/6711/2250/1437/71/5682/1844/1850/1848/5526/817/84292/7039/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/22866/5605/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/3563/1741/9542/2885/6709/8660/8826/5518/2252/4140/2253/3845/5623/3265/4763/3569/5696/5691/7314/3572/5515/5923/5718/818/57554/1839/3667/8823/8831/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/4902/2260/5528/2902/983/3718/2249/25780/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/80824/1445/5710/5719/2906/6233/51332/2266/2246/2251/5154/2243/1843/369/801/200734/7297/5781/8682/4747/11221/28956/805/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/409/5706/1438/673/2676/8315/2263/4233/84078/5714/6710/5688/5159/5687/5708/3084/5529/816/9693/9365/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/5924/7529/5595/25759/5516/8822/5786/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10817/10197/54518/2254/7316/10213/152831/1950/3560/57731/26281/10818/5715/8437/10256/2261/5701/5685/2255/8649/53358/5686/2066/6708/27006/5979/1742/5527/5716/88/5906/5155/9048/4254/399473/808/3559/5693/5721/5245/5156/161742/284 238 Human_SARS_coronavirus_2 R-HSA-5673001 RAF/MAP kinase cascade 233/7348 249/10654 6.125720923924596e-22 4.3308846932146895e-20 1.863508786330746e-20 5689/374/2674/4893/6711/2250/1437/71/5682/1844/1850/1848/5526/817/84292/7039/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/22866/5605/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/3563/1741/9542/2885/6709/8660/8826/5518/2252/4140/2253/3845/5623/3265/4763/5696/5691/7314/5515/5923/5718/818/57554/1839/3667/8823/8831/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/4902/2260/5528/2902/3718/2249/25780/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/80824/1445/5710/5719/2906/6233/51332/2266/2246/2251/5154/2243/1843/369/801/200734/8682/4747/11221/28956/805/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/409/5706/1438/673/2676/8315/2263/4233/84078/5714/6710/5688/5159/5687/5708/3084/5529/816/9693/9365/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/5924/7529/5595/25759/5516/8822/5786/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10817/10197/54518/2254/7316/10213/152831/1950/3560/57731/26281/10818/5715/8437/10256/2261/5701/5685/2255/8649/53358/5686/2066/6708/27006/5979/1742/5527/5716/88/5906/5155/9048/4254/399473/808/3559/5693/5721/5245/5156/161742/284 233 Human_SARS_coronavirus_2 R-HSA-5683057 MAPK family signaling cascades 270/7348 294/10654 8.363757992191979e-22 5.631597048075932e-20 2.423184019792964e-20 2308/5689/374/3725/2674/4893/6711/2250/1437/71/5682/1844/1850/1848/5526/817/84292/7039/27327/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/22866/5605/4609/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/192669/4296/5894/3563/1741/9542/2885/6709/8660/8997/8826/5518/2252/4140/4343/2253/3845/5623/3265/4763/3569/5062/5696/5691/7314/3572/5879/5515/5923/5718/818/57554/1839/3667/8823/8831/2065/5700/3815/122706/5707/5567/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/3337/4902/2260/5528/2902/983/3718/2249/25780/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/80824/1445/5710/8555/896/5719/2906/6233/51332/2266/2246/7514/2251/5154/2243/1843/26523/369/801/200734/7297/5781/8682/4747/11221/28956/805/9462/3562/6464/6712/2904/5747/283455/3674/7010/5568/2322/2675/3315/409/5706/1438/673/2676/8315/2263/4233/5597/84078/5714/5566/6710/5688/5159/5687/5708/3084/5063/5529/816/998/9693/9365/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/5058/5924/7529/5595/25759/5516/8822/5786/27161/815/5684/685/5720/2309/5604/3561/5525/153090/10642/10048/5690/57690/5717/9491/3568/8817/10817/10197/192670/5596/8550/54518/2254/7316/10213/152831/1950/3560/57731/26281/10818/5715/8437/10256/2261/5701/5685/2255/8649/53358/5686/2066/6708/27006/8556/5979/23112/1742/5527/5716/88/5906/5155/9048/4254/399473/808/3559/8202/5693/5721/5245/5156/161742/284 270 Human_SARS_coronavirus_2 R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 413/7348 473/10654 1.4630199232657317e-21 9.403228052262475e-20 4.046055098792311e-20 5295/3675/374/5777/627/3643/9252/4893/857/2250/2670/5335/71/5579/5770/5291/26469/1848/10653/256076/5578/7039/1785/5908/3082/117/51741/23385/2064/535/1280/1289/54845/5431/8829/50617/6696/6776/5435/3688/10312/5433/5753/5327/7423/4734/3709/10413/5605/3910/8569/1290/5898/1432/3908/3717/55824/145957/2534/9475/3690/9965/5439/2264/5603/3630/6456/83737/7072/9542/30011/2885/2475/8660/6093/163/7073/6196/9846/1759/5518/8440/2252/534/8874/9564/2253/6197/3845/1285/3265/1399/8877/5062/23769/51231/56034/5829/7314/5879/5515/6387/54106/255631/26999/51606/8038/1839/3918/161/5290/3667/5899/8823/6678/2065/5340/526/3815/5567/8027/10006/537/155066/3911/9550/1849/1284/2060/9114/5594/2069/8074/284217/9101/23118/57761/5921/6778/2260/5438/348/5528/9306/1500/3185/1298/11059/102/9261/525/2249/6714/2099/5664/2248/1447/5519/5598/4208/4670/2566/2247/4914/529/10810/10000/9146/6455/2335/64759/3909/6195/3728/8471/1445/533/84951/3925/6233/7525/7410/5580/2324/7409/2246/23191/3685/1292/2251/5154/57610/3932/1213/3791/1729/3710/1211/29924/1293/117145/1535/5600/1175/523/6300/528/801/200734/5781/30849/5663/2554/5725/1302/1291/10787/253260/805/25920/5170/1286/1173/116/4688/1287/2963/5434/5800/5590/6464/80310/85440/653361/5241/2904/6461/5747/5782/7424/135/5436/10193/5568/2322/7074/3315/10451/4318/382/1277/160/3912/1793/673/5140/527/6774/2263/4233/10152/6772/8651/26052/7867/64223/5566/2962/1003/8503/10126/5795/2889/5159/4067/3084/5063/5771/1111/5796/998/7058/3481/2886/3913/80004/208/9365/6654/5867/10718/79109/5900/7311/2185/387/1956/60/2549/51107/5058/1020/5432/3480/22916/11140/53916/7529/63916/5595/25759/5516/8822/1845/10253/9402/5440/1282/8065/685/85301/23543/1495/5604/1499/4690/1299/5430/10048/10273/207/7422/10458/5045/2562/3178/8817/10817/3708/5441/58513/2254/4686/7316/152831/1950/9611/127124/51072/4205/5289/57498/3915/1301/10768/5046/26281/10818/1281/1297/8936/3673/23545/2261/867/5437/466/90423/245972/2255/53358/3320/8992/4846/4803/2066/3914/27006/6285/1742/200958/1398/3187/1385/9844/5228/5906/3479/5155/23163/50509/4254/8851/5296/5581/245973/581/808/10076/131873/1536/7057/1278/11033/10319/10254/6457/51382/5156/161742/9296/2887/2242 413 Human_SARS_coronavirus_2 R-HSA-168254 Influenza Infection 152/7348 155/10654 3.628421447434846e-21 2.2306904029012487e-19 9.598295636692639e-20 3839/6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/116832/23225/6192/6156/6143/5439/3836/6139/9972/3921/8021/7040/55746/6208/6170/3303/6203/402569/6147/6222/8106/9636/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/7514/140032/1213/5610/1211/6188/6396/129401/200916/6122/6230/4928/2963/3838/5434/5903/6194/55706/7175/6166/5436/6136/3841/6125/821/6232/6160/293/5611/6193/4927/6210/6229/6205/2962/10898/3840/140801/6235/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/81929/5440/9349/4736/2926/51121/9631/6159/6217/3843/5430/6152/51065/6141/79023/6123/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 152 Human_SARS_coronavirus_2 R-HSA-199977 ER to Golgi Anterograde Transport 151/7348 154/10654 5.192705037091994e-21 3.0593687176866993e-19 1.3163962769470053e-19 6811/23256/374/6711/11014/126003/10960/2153/51807/286/10484/7039/347688/5861/10381/7278/1780/9570/90411/8655/84516/832/3998/55738/7846/51226/9382/375056/9632/3630/81027/6709/79090/10652/54732/51272/51164/58485/1294/79861/9117/10342/128637/2801/377/10466/22872/1315/81562/8615/55014/11316/91949/8729/254263/23423/10376/1314/10540/51332/83696/51128/27095/6399/7109/378/6396/26286/1453/26958/10175/140735/10959/2348/84364/22820/84617/22796/11258/6712/2890/1783/10382/10802/93661/55860/2157/830/7277/10671/9554/966/11196/1639/149111/10282/6710/8775/81876/11015/347733/51143/79748/51693/23243/5537/9871/10383/84790/10945/1075/7280/829/1778/9919/10113/51399/11070/25839/55291/51014/122553/26984/83548/63908/112714/1604/1781/57731/1522/10121/2804/9527/57511/22870/5265/8774/10972/381/6708/4905/89866/9276/287/375/84342/64689/288/10427/22818/372 151 Human_SARS_coronavirus_2 R-HSA-2555396 Mitotic Metaphase and Anaphase 192/7348 202/10654 1.3186067216283311e-20 7.458039617529841e-19 3.2090723583207387e-19 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/10381/57122/5705/7278/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/5520/81027/51529/4001/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/221496/7444/5698/5692/5713/91687/119504/11243/10376/5710/7324/2010/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/26271/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/347733/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/79023/55920/10735/10197/112714/23141/1781/7316/10213/4085/55166/5715/5701/5685/8815/5686/79003/9126/9232/23592/9700/5527/5716/701/57551/5693/5721 192 Human_SARS_coronavirus_2 R-HSA-68882 Mitotic Anaphase 191/7348 201/10654 1.8317277188532075e-20 9.961780747917059e-19 4.286391180150421e-19 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/10381/57122/5705/7278/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/5520/81027/51529/4001/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/221496/7444/5698/5692/5713/91687/119504/11243/10376/5710/7324/2010/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/347733/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/79023/55920/10735/10197/112714/23141/1781/7316/10213/4085/55166/5715/5701/5685/8815/5686/79003/9126/9232/23592/9700/5527/5716/701/57551/5693/5721 191 Human_SARS_coronavirus_2 R-HSA-68877 Mitotic Prometaphase 190/7348 200/10654 2.5437709344199067e-20 1.3321822597295365e-18 5.732162183605093e-19 114791/10844/55839/11130/440145/6249/9735/7531/1459/11190/203068/5526/54801/51807/9212/347688/10274/1460/147841/348995/79441/10381/57122/5116/7278/1780/23122/5048/57405/8655/1457/23279/9702/2491/7846/7840/1060/11064/81027/11004/9184/5518/55835/29922/23332/25909/10726/81930/55746/93323/5515/79682/10403/79861/64151/25936/55869/1454/3619/64105/332/10051/5528/983/79902/3796/79959/5519/81565/80097/91687/11243/10376/23397/10540/85378/83540/7514/54930/54820/113130/6396/1453/27229/64946/9793/140735/220134/84617/4928/5903/11258/22981/55055/8636/80776/1783/401541/7532/55125/10382/79172/121441/7277/9133/79980/6232/23047/9814/653784/5885/23354/891/5501/9738/1639/55722/4957/5566/54821/9183/1062/699/7283/347733/22919/8243/10426/5529/22994/51143/1069/5577/10383/5347/84790/84643/80184/22897/5108/10592/7280/10806/1778/5516/115106/4926/5905/22995/55559/81929/54908/55143/5525/10142/1058/991/79019/348235/80152/1063/8379/95681/23244/23421/79023/55920/10735/112714/1781/80321/4085/55166/10121/84131/3320/79003/9126/9918/10733/4751/5527/27175/80254/701/57551/9662/55142/8481/55755 190 Human_SARS_coronavirus_2 R-HSA-453274 Mitotic G2-G2/M phases 188/7348 198/10654 4.901422134142843e-20 2.4752181777421357e-18 1.0650458622310387e-18 114791/10844/8454/5689/440145/5682/7531/11190/203068/54801/51807/63943/347688/51400/79441/143471/10381/5705/5116/7278/5048/5709/9978/1869/5695/8655/6790/9702/5711/5928/7846/7840/5683/5699/11064/5702/5520/81027/8900/5518/55835/29922/23332/7465/93323/5696/5691/7314/5515/5718/8945/79861/4659/5700/122706/5707/1454/23198/993/890/983/9861/79959/5519/5698/5692/5713/80097/10376/5710/10540/7157/85378/5719/6233/7514/54930/54820/1453/27229/9793/4218/5500/84617/2305/11258/22981/8636/51512/7532/84962/55125/10382/121441/7277/5706/9133/286826/9814/653784/23354/728642/891/9738/4331/1639/5714/55722/4957/5566/5688/5687/7283/347733/5708/22919/984/10426/22994/79866/1069/5577/5704/3326/7311/10133/10383/5347/84790/80184/5694/22897/5108/4660/7280/10806/1778/5516/115106/1017/22822/22995/55559/5684/994/5720/4605/902/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/112714/1781/7316/10213/80321/1026/10121/1871/5715/84131/5701/23291/5685/3320/5686/2033/995/10733/4751/27175/80254/5716/23194/9662/55142/1022/8481/5693/5721/55755 188 Human_SARS_coronavirus_2 R-HSA-194840 Rho GTPase cycle 136/7348 138/10654 7.433524290053297e-20 3.62448391246047e-18 1.5595560942471164e-18 57569/9639/7984/394/398/57522/392/55789/29/2909/55160/613/1894/388/116985/54509/10276/84033/10144/5881/100271715/9138/143872/115703/23365/171177/26230/9322/397/57449/51291/23433/8997/26084/8874/121512/64857/9411/2665/5879/10395/9181/64333/55843/9938/257106/2245/389/29127/84904/89839/1124/84144/6453/9828/55114/57636/396/5880/85360/158763/57584/58504/7410/7409/4649/51306/29984/128272/91614/25791/55701/9886/2664/80728/9743/445328/9912/7204/64411/3633/27237/7074/10451/58480/117289/50650/9754/221472/23229/393/55288/4650/94134/22899/57514/998/6654/57381/387/54848/6655/389337/5924/93663/57580/10928/9459/11214/23370/116984/9824/4168/23263/50649/79658/9826/23092/1123/391/23221/89941/2/90627/83478/23380/5296/84986/395/201176/89846/399/4952/4983/9901/10672 136 Human_SARS_coronavirus_2 R-HSA-2467813 Separation of Sister Chromatids 181/7348 190/10654 7.90392586792415e-20 3.7253837257482496e-18 1.6029716321614594e-18 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/10381/57122/5705/7278/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/81027/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/5698/5692/5713/91687/119504/11243/10376/5710/7324/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/347733/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7280/1778/5516/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/79023/55920/10735/10197/112714/1781/7316/10213/4085/55166/5715/5701/5685/5686/79003/9126/9232/9700/5527/5716/701/57551/5693/5721 181 Human_SARS_coronavirus_2 R-HSA-69275 G2/M Transition 186/7348 196/10654 9.432756250657433e-20 4.302553980138584e-18 1.8513185442716457e-18 114791/10844/8454/5689/440145/5682/7531/11190/203068/54801/51807/63943/347688/51400/79441/143471/10381/5705/5116/7278/5048/5709/9978/5695/8655/6790/9702/5711/5928/7846/7840/5683/5699/11064/5702/5520/81027/8900/5518/55835/29922/23332/7465/93323/5696/5691/7314/5515/5718/8945/79861/4659/5700/122706/5707/1454/23198/993/890/983/9861/79959/5519/5698/5692/5713/80097/10376/5710/10540/7157/85378/5719/6233/7514/54930/54820/1453/27229/9793/4218/5500/84617/2305/11258/22981/8636/51512/7532/84962/55125/10382/121441/7277/5706/9133/286826/9814/653784/23354/728642/891/9738/4331/1639/5714/55722/4957/5566/5688/5687/7283/347733/5708/22919/984/10426/22994/79866/1069/5577/5704/3326/7311/10133/10383/5347/84790/80184/5694/22897/5108/4660/7280/10806/1778/5516/115106/1017/22822/22995/55559/5684/994/5720/4605/902/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/112714/1781/7316/10213/80321/1026/10121/5715/84131/5701/23291/5685/3320/5686/2033/995/10733/4751/27175/80254/5716/23194/9662/55142/1022/8481/5693/5721/55755 186 Human_SARS_coronavirus_2 R-HSA-69306 DNA Replication 126/7348 127/10654 1.358458991063366e-19 6.0026906667612484e-18 2.5828595290612684e-18 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/143471/5705/5709/5422/9978/1869/4174/5695/84515/4998/5711/10926/5683/990/5699/5702/8900/51529/29945/51434/55388/84296/6117/29882/5001/10714/5558/5696/5691/7314/996/5718/6118/23594/5700/122706/5707/64785/23198/898/3978/5557/890/51433/9861/6502/5698/5692/5985/5713/119504/4175/5710/5984/7324/5719/64682/6233/23649/5424/4999/4172/5000/8318/246184/54107/4173/5706/8881/5425/5714/5111/51053/6119/5688/5687/5427/5708/81620/10393/1870/5704/29935/51343/23595/7311/25906/51659/5983/5694/4176/56655/1017/5684/5720/57804/8317/9837/5690/5717/9491/6500/10197/7316/10213/5426/4171/1871/5715/5701/5685/5686/5716/5981/5693/5721 126 Human_SARS_coronavirus_2 R-HSA-168255 Influenza Life Cycle 141/7348 144/10654 1.8536187681549524e-19 7.942475570215463e-18 3.4175172184802634e-18 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/116832/23225/6192/6156/6143/5439/3836/6139/9972/3921/8021/55746/6208/6170/3303/6203/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/7514/140032/1213/1211/6188/6396/129401/200916/6122/6230/4928/2963/5434/5903/6194/55706/7175/6166/5436/6136/6125/821/6232/6160/5611/6193/4927/6210/6229/6205/2962/140801/6235/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/81929/5440/9349/4736/2926/51121/9631/6159/6217/3843/5430/6152/51065/6141/79023/6123/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 141 Human_SARS_coronavirus_2 R-HSA-8856688 Golgi-to-ER retrograde transport 131/7348 133/10654 4.55244647698444e-19 1.893282152487058e-17 8.146483169340578e-18 11014/64837/11127/51807/53407/347688/3798/5861/10381/7278/1780/5048/8655/84516/832/285643/55738/10112/636/64147/7846/2590/51226/81027/11004/56894/10749/81930/54732/51164/60561/113220/79861/3797/29127/55605/23299/377/8398/1315/3796/5870/124602/11316/55614/89953/56992/8729/23423/10376/1314/10540/3835/147700/3833/378/9493/26286/26958/140735/10959/3831/84364/22820/84617/2589/11258/1783/55850/9585/10382/93661/55860/830/3832/7277/10671/9554/23303/1639/8775/26153/81876/9183/1062/11015/146909/347733/662/90990/51143/23046/10383/24137/84790/84643/10945/5049/51594/22920/7280/829/22931/1778/55582/5321/9371/51014/23095/5050/63908/112714/1781/22930/25782/10121/6836/547/51560/8774/10972/381/4905/3834/9276/55083/3799/375/221458/22818/372 131 Human_SARS_coronavirus_2 R-HSA-8856828 Clathrin-mediated endocytosis 142/7348 146/10654 1.5122626519586412e-18 6.10954111391291e-17 2.6288355273145703e-17 5869/374/85439/71/8674/5286/4738/1212/7039/23208/27348/1785/29763/950/8871/10094/554/54874/55738/10980/22848/7037/2017/3482/408/9322/10987/6456/185/8976/30011/2885/163/11037/1759/23149/3312/29993/9185/7314/9856/23396/1839/161/7018/25977/5868/10618/10093/8027/1856/9892/8322/2060/2069/1601/6453/55707/8301/1129/9146/6455/4074/10920/26119/29979/6233/90019/7474/6844/1213/2580/1211/29924/4036/1175/85021/10109/6869/1173/6857/84251/23048/9026/29988/409/112574/382/160/338/8218/920/22905/26052/8867/10092/9829/2873/10097/7311/1956/60/8533/274/51429/8673/3092/50618/51138/9318/685/127833/1080/29978/58513/7316/1950/273/64708/10552/26130/3267/3949/867/9341/915/917/6572/115548/5878/1861/10096/143425/3575/6845/551/154/10254/6457/50813/4952/11252 142 Human_SARS_coronavirus_2 R-HSA-69239 Synthesis of DNA 118/7348 119/10654 2.5929238781283103e-18 9.648406220193238e-17 4.151551250853639e-17 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/143471/5705/5709/5422/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/84296/6117/29882/5001/10714/5558/5696/5691/7314/996/5718/6118/23594/5700/122706/5707/64785/23198/898/3978/5557/890/51433/9861/6502/5698/5692/5985/5713/119504/4175/5710/5984/7324/5719/64682/6233/23649/5424/4999/4172/5000/8318/246184/54107/4173/5706/8881/5425/5714/5111/6119/5688/5687/5427/5708/81620/10393/5704/51343/23595/7311/25906/51659/5983/5694/4176/56655/1017/5684/5720/57804/9837/5690/5717/9491/6500/10197/7316/10213/5426/4171/5715/5701/5685/5686/5716/5981/5693/5721 118 Human_SARS_coronavirus_2 R-HSA-72613 Eukaryotic Translation Initiation 118/7348 119/10654 2.5929238781283103e-18 9.648406220193238e-17 4.151551250853639e-17 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/116832/6192/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/140032/51386/6188/1978/200916/6122/1968/6230/8669/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/8893/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/8891/51121/6159/6217/6152/51065/6141/10480/6123/1967/6164/8661/9669/6209/1964/11224/6165/6130/8890/6204/6228/6124/3646/6189/6135/6201/6161/8892/6133 118 Human_SARS_coronavirus_2 R-HSA-72737 Cap-dependent Translation Initiation 118/7348 119/10654 2.5929238781283103e-18 9.648406220193238e-17 4.151551250853639e-17 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/116832/6192/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/140032/51386/6188/1978/200916/6122/1968/6230/8669/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/8893/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/8891/51121/6159/6217/6152/51065/6141/10480/6123/1967/6164/8661/9669/6209/1964/11224/6165/6130/8890/6204/6228/6124/3646/6189/6135/6201/6161/8892/6133 118 Human_SARS_coronavirus_2 R-HSA-168273 Influenza Viral RNA Transcription and Replication 131/7348 134/10654 6.494916251431266e-18 2.354823481929182e-16 1.0132419954999385e-16 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/116832/23225/6192/6156/6143/5439/6139/9972/3921/8021/55746/6208/6170/6203/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/140032/6188/6396/129401/200916/6122/6230/4928/2963/5434/5903/6194/55706/7175/6166/5436/6136/6125/6232/6160/5611/6193/4927/6210/6229/6205/2962/140801/6235/6181/8086/7311/6223/25873/9045/6187/5432/6168/6157/6137/6144/81929/5440/9349/4736/2926/51121/9631/6159/6217/3843/5430/6152/51065/6141/79023/6123/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 131 Human_SARS_coronavirus_2 R-HSA-376176 Signaling by ROBO receptors 202/7348 218/10654 8.940077571599577e-18 3.16031742156045e-16 1.3598328516801462e-16 6158/5689/6138/6227/7852/6206/6234/6191/6128/5682/6132/57522/10298/6129/6176/5578/9353/6224/6146/6154/26986/143471/6202/5705/6169/8829/23122/5709/6175/9978/6218/5695/65109/6173/6167/5711/116832/1605/5683/6192/6156/5699/6143/9495/5702/6139/10487/8440/3921/23332/5062/6208/5696/6170/5691/7314/5879/6387/5718/25/6092/6203/8861/6147/5700/122706/5707/5567/89884/6222/23198/27/26019/2935/6134/6091/22794/6155/4116/6714/6231/9861/6142/23521/10486/5698/5692/5713/1981/5710/6207/5719/6233/140032/6188/5217/200916/6122/80728/6230/1287/6194/2107/9423/6166/6136/5568/6125/5706/6232/6160/55110/5714/6193/6210/6229/6205/5566/4650/5688/5687/5708/5063/140801/6235/6181/998/9939/6654/5704/7311/6223/25873/387/6655/23708/5694/5058/9045/6187/65110/6168/22916/6157/6137/4440/10921/6144/55740/23032/5684/9349/4736/5720/51121/2817/6159/4690/6217/6152/5690/5532/5717/9491/51065/6141/23053/6123/10197/6164/4686/7316/10213/5216/6209/11224/6165/6130/5715/6204/5701/6228/5576/5685/51466/5686/7408/6124/8453/5716/23380/1630/6189/9775/6135/6201/4753/6161/5693/5721/6133/9901 202 Human_SARS_coronavirus_2 R-HSA-927802 Nonsense-Mediated Decay (NMD) 114/7348 115/10654 1.1298329519311279e-17 3.8037709381681303e-16 1.6367003664566213e-16 6158/9887/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/55629/6169/6175/6218/65109/6173/6167/116832/6192/6156/6143/5520/6139/23381/5518/3921/6208/6170/5515/6203/6147/6222/26019/2935/6134/22794/6155/4116/6231/6142/23521/1981/6207/6233/140032/6188/23049/5976/200916/6122/6230/6194/2107/6166/56006/6136/6125/6232/6160/55110/6193/6210/6229/6205/55181/140801/6235/6181/9939/7311/6223/25873/23708/9045/6187/65110/6168/22916/6157/6137/10921/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/4686/6209/11224/6165/6130/6204/6228/55802/6124/6189/23293/9775/6135/6201/6161/6133 114 Human_SARS_coronavirus_2 R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 114/7348 115/10654 1.1298329519311279e-17 3.8037709381681303e-16 1.6367003664566213e-16 6158/9887/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/55629/6169/6175/6218/65109/6173/6167/116832/6192/6156/6143/5520/6139/23381/5518/3921/6208/6170/5515/6203/6147/6222/26019/2935/6134/22794/6155/4116/6231/6142/23521/1981/6207/6233/140032/6188/23049/5976/200916/6122/6230/6194/2107/6166/56006/6136/6125/6232/6160/55110/6193/6210/6229/6205/55181/140801/6235/6181/9939/7311/6223/25873/23708/9045/6187/65110/6168/22916/6157/6137/10921/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/4686/6209/11224/6165/6130/6204/6228/55802/6124/6189/23293/9775/6135/6201/6161/6133 114 Human_SARS_coronavirus_2 R-HSA-3858494 Beta-catenin independent WNT signaling 141/7348 146/10654 2.000812269112051e-17 6.579415229126605e-16 2.831014667189145e-16 2788/5689/2780/5158/5579/5682/5331/1212/5578/81029/5582/27327/143471/5705/2775/5530/5709/5695/3709/5881/5711/5683/5699/2782/5702/192669/57216/1855/6932/163/4343/3845/5696/5691/4920/7314/5879/2787/5718/51176/2535/161/51701/5700/122706/5707/1856/8322/23198/10681/7471/83439/8323/2792/9861/8321/7481/5698/5880/5692/5713/2785/2783/23002/2784/5710/5719/6233/7474/1857/1213/3710/1211/7855/1175/26523/801/2791/7976/805/5145/1173/144165/4772/409/5706/160/5714/6934/5688/5687/5148/4919/23236/5708/2786/5704/7311/387/5694/57154/27161/815/5684/5720/54331/6885/1499/59345/5690/5532/57690/5717/9491/50855/51764/94235/3708/5330/10197/192670/64750/7316/10213/55970/54361/5216/5715/5701/2793/5685/5686/23112/23513/5716/808/5693/5721/6259/2790/5592 141 Human_SARS_coronavirus_2 R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 111/7348 112/10654 3.4033357510497804e-17 1.0937083527237248e-15 4.706048000255438e-16 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/6202/6169/6175/6218/6173/6167/116832/6192/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/140032/51386/6188/200916/6122/1968/6230/8669/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/9669/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 111 Human_SARS_coronavirus_2 R-HSA-8868773 rRNA processing in the nucleus and cytosol 182/7348 195/10654 4.819741030283174e-17 1.5105083036674038e-15 6.499469958458717e-16 6158/5393/6138/6227/6206/6234/6191/6128/6132/10557/6129/23404/55226/6176/10528/84135/27340/27043/55623/6224/6146/6154/88745/6202/51096/6169/55272/6175/6218/5394/6173/11102/6167/28987/116832/23481/6192/51077/6156/117246/6143/6139/79159/23160/26168/11340/3921/10607/10799/11103/51388/6208/6170/22984/10813/9136/6203/51504/23246/54913/54433/6147/8568/27292/6222/1454/56902/51602/6134/6155/9724/6231/6142/23521/54555/10171/5822/6207/10969/10556/6233/140032/6188/79707/54881/1453/4691/23016/118460/200916/6122/79897/6230/2091/55651/55127/8602/6194/6166/10436/8780/9277/84128/6136/6125/4839/6232/134430/6160/92856/65083/6193/10200/6210/6229/6205/11056/9790/55131/140801/6235/55720/6181/55759/705/7311/6223/25873/55505/51010/26354/56915/51202/9045/57647/6187/6168/6157/6137/79050/22894/84946/6144/9349/55813/4736/57418/22803/51121/6159/25879/6217/81887/6152/57050/51065/6141/6123/55781/6164/6209/11224/6165/6130/6204/1736/6228/10438/10199/51013/6124/25926/83732/27341/6189/6135/6201/6161/54512/10885/6133/9188 182 Human_SARS_coronavirus_2 R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 110/7348 111/10654 4.9139591208416247e-17 1.5105083036674038e-15 6.499469958458717e-16 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/116832/6192/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/23521/8894/1981/6207/1977/6233/140032/51386/6188/200916/6122/1968/6230/8669/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 110 Human_SARS_coronavirus_2 R-HSA-69242 S Phase 153/7348 161/10654 1.2717145223070095e-16 3.8259666692385346e-15 1.646250826189141e-15 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/10274/5925/143471/5705/5709/5422/9978/1869/4174/5753/5695/84515/4609/4998/5711/5928/5683/990/5699/5702/8900/51529/29945/51434/84296/157570/6117/29882/5001/10714/7465/5558/5696/5691/7314/996/5718/6118/23594/7027/5700/122706/5707/64785/23198/898/3978/5934/5557/993/890/51433/9861/2932/6502/5698/10000/5692/5985/5713/119504/595/4175/5710/5984/7324/5719/64682/6233/113130/23649/1163/5424/4999/4172/1019/5000/8318/246184/54107/4173/5706/286826/23047/8881/5885/4331/5425/5714/5111/6119/5688/5687/5427/5708/1874/8243/81620/10393/208/5704/51343/23595/7311/25906/51659/5983/5694/4176/56655/1017/5684/994/5720/902/57804/207/9837/5690/5717/1027/9491/6500/23244/10735/10197/4149/7316/10213/1026/5426/4171/5715/5701/5685/5686/9126/5716/114799/5981/1022/5693/5721 153 Human_SARS_coronavirus_2 R-HSA-6807070 PTEN Regulation 135/7348 140/10654 1.557923677984882e-16 4.589383501397132e-15 1.9747365918317146e-15 1912/5689/3725/6591/5682/1822/1459/9112/6045/27327/80012/1460/143471/5705/5709/5695/1457/1911/4734/11060/5711/5928/10325/5683/23512/57332/5699/2444/5702/192669/1107/8975/5371/2475/1386/10670/4343/80351/64121/5696/5691/7314/5718/23186/5700/122706/5707/2146/51564/5594/84232/23198/100532731/9861/7101/81847/84733/57459/5698/10000/5692/5713/5710/3066/7157/5719/6233/331/8726/26523/7874/57521/23608/6015/28956/9219/8535/5931/58528/5706/8658/5714/1108/2122/64223/10014/5688/5687/5708/54815/6009/208/5704/55004/57504/7311/648/5694/23466/53615/5595/27161/5684/8841/5720/5468/5978/10273/207/5690/57690/5717/9491/10197/192670/153129/7316/10213/57167/5715/1958/5701/5685/8649/5686/5728/6615/3065/23028/5987/23112/10542/5716/5693/5721 135 Human_SARS_coronavirus_2 R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 173/7348 185/10654 1.6938565168195301e-16 4.8879859485363584e-15 2.1032203366738743e-15 6158/5393/6138/6227/6206/6234/6191/6128/6132/10557/6129/23404/6176/10528/84135/27340/27043/6224/6146/6154/88745/6202/51096/6169/55272/6175/6218/5394/6173/11102/6167/28987/116832/23481/6192/51077/6156/117246/6143/6139/79159/23160/26168/11340/3921/10607/10799/11103/51388/6208/6170/22984/10813/9136/6203/23246/54913/6147/8568/6222/1454/56902/51602/6134/6155/9724/6231/6142/23521/54555/10171/5822/6207/10969/10556/6233/140032/6188/79707/54881/1453/4691/23016/118460/200916/6122/79897/6230/2091/55127/8602/6194/6166/10436/8780/9277/84128/6136/6125/6232/134430/6160/92856/65083/6193/10200/6210/6229/6205/11056/9790/55131/140801/6235/55720/6181/55759/705/7311/6223/25873/51010/26354/56915/51202/9045/57647/6187/6168/6157/6137/79050/22894/84946/6144/9349/55813/4736/57418/22803/51121/6159/25879/6217/81887/6152/57050/51065/6141/6123/55781/6164/6209/11224/6165/6130/6204/6228/10438/10199/51013/6124/25926/83732/27341/6189/6135/6201/6161/54512/10885/6133/9188 173 Human_SARS_coronavirus_2 R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 110/7348 112/10654 8.79982444593876e-16 2.4885903533114813e-14 1.0707996904742324e-14 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/55176/6224/6146/6154/6202/6169/6175/6218/6728/6173/6167/116832/6192/6156/6143/6139/6745/3921/23478/6208/6170/6203/10952/6147/6222/6727/6184/58477/6134/6747/6731/6155/6729/6231/6142/23521/6185/6207/6726/6233/140032/6188/200916/6122/6230/6194/6166/1650/6136/6125/6232/6160/6748/29927/60559/6746/6193/6210/6229/6205/28972/140801/6235/6181/23471/7311/6223/25873/6730/90701/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/23480/6164/6209/11224/6165/6130/6204/6228/6124/6189/9789/6135/6201/6161/6133 110 Human_SARS_coronavirus_2 R-HSA-72689 Formation of a pool of free 40S subunits 100/7348 101/10654 1.9217469013009455e-15 5.328137487136347e-14 2.2926103383941106e-14 6158/6138/6227/6206/6234/27335/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/6202/6169/6175/6218/6173/6167/116832/6192/6156/6143/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/8663/23521/6207/6233/140032/51386/6188/200916/6122/6230/8669/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/8664/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6123/6164/8661/6209/1964/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 100 Human_SARS_coronavirus_2 R-HSA-9010553 Regulation of expression of SLITs and ROBOs 160/7348 171/10654 2.0600373517906708e-15 5.601716952753863e-14 2.4103271039170198e-14 6158/5689/6138/6227/6206/6234/6191/6128/5682/6132/6129/6176/9353/6224/6146/6154/26986/143471/6202/5705/6169/5709/6175/9978/6218/5695/65109/6173/6167/5711/116832/1605/5683/6192/6156/5699/6143/5702/6139/3921/6208/5696/6170/5691/7314/5718/6092/6203/8861/6147/5700/122706/5707/89884/6222/23198/26019/2935/6134/6091/22794/6155/4116/6231/9861/6142/23521/5698/5692/5713/1981/5710/6207/5719/6233/140032/6188/200916/6122/6230/1287/6194/2107/6166/6136/6125/5706/6232/6160/55110/5714/6193/6210/6229/6205/5688/5687/5708/140801/6235/6181/9939/5704/7311/6223/25873/23708/5694/9045/6187/65110/6168/22916/6157/6137/4440/10921/6144/23032/5684/9349/4736/5720/51121/6159/6217/6152/5690/5717/9491/51065/6141/23053/6123/10197/6164/4686/7316/10213/6209/11224/6165/6130/5715/6204/5701/6228/5685/5686/6124/8453/5716/6189/9775/6135/6201/6161/5693/5721/6133 160 Human_SARS_coronavirus_2 R-HSA-453279 Mitotic G1-G1/S phases 141/7348 149/10654 6.28878460838809e-15 1.6778002709925962e-13 7.219299907941046e-14 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/1031/4998/5711/5928/10926/3717/5683/990/5699/5702/5520/8900/55388/1032/1030/5518/6117/5001/7465/5558/5696/5691/7314/5515/6241/5718/6118/25/23594/7027/5700/5707/7153/898/5934/5557/993/890/1876/983/6714/9861/5519/6502/5698/10000/5692/5713/595/4175/5710/896/5719/6233/7298/23649/1719/1163/1859/4999/4172/26271/1019/5000/8318/1029/54107/4173/5706/286826/891/4331/5714/5111/51053/6119/5688/5687/5427/4067/5708/1874/81620/208/1870/5704/29935/23595/7311/5694/4176/5516/56655/1017/894/5684/5720/4605/902/8317/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1026/5933/5426/4171/1871/5715/5701/5685/5686/1021/3065/5716/1022/5693/5721/7083/1028 141 Human_SARS_coronavirus_2 R-HSA-5610787 Hedgehog 'off' state 110/7348 113/10654 1.0601469076149555e-14 2.776014309939902e-13 1.1944735138429715e-13 8454/5689/57728/5682/11127/1452/51684/143471/10381/5705/7278/5709/9978/5695/107/5711/7846/5683/5699/5702/81027/83737/5696/5691/7314/5718/8945/79659/5700/122706/5707/5567/27152/23198/112/5573/2737/5727/8650/111/9861/2932/5698/5692/5713/10376/5710/5719/6233/374654/55764/23322/196883/115/84617/54903/10382/79809/5568/8100/7277/5706/113/5714/5566/2736/5688/5687/347733/5708/55811/5577/5704/7311/10383/84790/5694/7280/109/5684/5720/55081/2735/5575/6608/5690/5717/9491/6500/57539/114/7289/10197/108/7316/10213/2778/5715/5701/5576/5685/5686/9742/5716/80199/23432/8481/5693/5721/26160 110 Human_SARS_coronavirus_2 R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 94/7348 95/10654 1.722826442949801e-14 4.429230164238216e-13 1.905825232583704e-13 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/6173/6167/116832/6192/6156/6143/6139/3921/6208/6170/6203/6147/6222/2935/6134/6155/6231/6142/23521/1981/6207/6233/140032/6188/5976/200916/6122/6230/6194/2107/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/23708/9045/6187/6168/22916/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/4686/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 94 Human_SARS_coronavirus_2 R-HSA-5617833 Cilium Assembly 183/7348 201/10654 3.5566930451055403e-14 8.867950309943352e-13 3.8157338488403616e-13 55763/57728/1260/79867/7531/11190/203068/11127/54801/51807/1258/123016/85302/347688/1262/79441/10381/5116/7278/5048/10576/22832/60412/8655/83658/6010/54585/51668/9702/132320/7846/7840/11064/84902/81027/84100/2847/5518/55835/57560/23332/166379/93323/79659/79861/3797/84747/11020/10575/1454/9321/150737/10013/54806/9727/91147/983/79959/5310/92104/8729/10376/10540/11336/117177/57545/26005/54930/55764/54820/23322/378/56623/1453/56912/9793/4218/140735/6102/80173/582/84617/90410/11258/22981/8636/54903/80776/3842/7532/55125/10382/6753/79809/8100/121441/7277/26146/585/9814/5147/23354/146057/9738/1639/255758/55722/4957/50807/5566/7283/347733/22919/27077/22994/4867/5311/1069/5577/10383/583/5347/403/84790/22948/80184/22897/22920/5108/261734/57787/7280/10806/9657/1778/55770/23265/115106/10694/22995/55559/9371/55081/28981/10142/6608/10640/27031/51134/95681/57539/79989/112714/7203/1781/80321/8766/79598/149371/10121/347240/84131/6950/55212/3320/79600/10733/4751/9742/80254/200894/26123/54536/9662/55142/92482/129880/8481/27241/51259/55755/64792/26160 183 Human_SARS_coronavirus_2 R-HSA-156842 Eukaryotic Translation Elongation 92/7348 93/10654 3.574774877417051e-14 8.867950309943352e-13 3.8157338488403616e-13 6158/6138/6227/6206/6234/6191/6128/6132/1917/6129/1915/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6192/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/140032/6188/200916/6122/6230/6194/6166/1938/6136/6125/1937/6232/6160/1933/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/1936/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 92 Human_SARS_coronavirus_2 R-HSA-6807878 COPI-mediated anterograde transport 99/7348 101/10654 4.479962775803107e-14 1.092184028445792e-12 4.699489082421408e-13 6811/6711/11014/51807/286/347688/5861/10381/7278/1780/9570/8655/84516/832/55738/7846/51226/9382/3630/81027/6709/10652/54732/51272/51164/79861/2801/377/10466/1315/8615/11316/91949/8729/23423/10376/1314/10540/51332/378/26286/26958/140735/10959/2348/84364/22820/84617/22796/11258/6712/1783/10382/93661/55860/830/7277/10671/966/1639/10282/6710/8775/81876/11015/347733/51143/10383/84790/10945/7280/829/1778/11070/25839/51014/83548/63908/112714/1604/1781/57731/10121/2804/9527/57511/8774/10972/381/6708/4905/9276/287/375/84342/64689/288/22818/372 99 Human_SARS_coronavirus_2 R-HSA-72312 rRNA processing 186/7348 205/10654 5.1900421622484143e-14 1.2438507826134334e-12 5.352086297555011e-13 6158/5393/6138/6227/6206/6234/6191/6128/79922/6132/10557/6129/23404/55226/6176/10528/84135/27340/27043/55623/6224/6146/6154/88745/6202/51096/6169/55272/6175/6218/5394/6173/11102/6167/28987/116832/23481/6192/51077/6156/117246/6143/6139/79159/23160/26168/11340/3921/10607/10799/11103/51388/6208/6170/22984/10813/60528/9136/6203/51504/23246/54913/54433/6147/8568/27292/6222/1454/56902/51602/6134/6155/9724/6231/6142/23521/54555/10171/5822/6207/10969/10556/6233/140032/6188/79707/54881/1453/4691/23016/118460/200916/6122/79897/6230/2091/55651/55127/8602/6194/6166/3028/10436/8780/9277/84128/6136/6125/4839/6232/134430/6160/92856/65083/6193/10200/6210/6229/6205/11056/9790/55131/140801/6235/55720/6181/55759/705/7311/6223/25873/55505/51010/26354/56915/51202/9045/57647/6187/6168/6157/6137/79050/22894/84946/6144/9349/55813/4736/57418/22803/51121/6159/25879/6217/81887/6152/57050/51065/6141/6123/55781/6164/54931/6209/11224/6165/6130/6204/1736/6228/10438/10199/51013/6124/25926/83732/27341/6189/6135/6201/6161/54512/10885/6133/9188 186 Human_SARS_coronavirus_2 R-HSA-8957275 Post-translational protein phosphorylation 105/7348 108/10654 6.069427639205484e-14 1.4303617803060924e-12 6.154612588527667e-13 56955/4240/3270/9210/10272/2153/7857/29106/91851/6696/51156/1435/265/11098/10130/2200/80341/375056/1114/720/10117/3956/3569/54972/2519/8720/7018/10618/11167/813/5179/8074/51246/348/4924/3484/102/8614/336/6694/4148/174/57104/2335/7466/116519/2266/51280/7076/2243/84141/3488/8542/4221/351/4052/7184/56975/334/3912/338/64856/335/5611/197/3053/3895/5624/1000/54757/8404/255738/3913/652/57719/147111/2719/3487/3371/54587/401138/3486/7425/6383/3827/3490/5589/2621/3915/5768/1471/1462/10232/462/3698/5265/1758/258/11320/5954/213/10970/5034/1356/718 105 Human_SARS_coronavirus_2 R-HSA-162909 Host Interactions of HIV factors 123/7348 129/10654 6.28141244555664e-14 1.4560519996749327e-12 6.265153396948643e-13 23165/5689/162/5682/1174/348995/143471/57122/5705/23511/5709/9978/5695/292/567/23279/5711/23225/5683/2534/5699/5702/3836/163/9972/8021/1794/904/55690/5062/55746/5696/5691/7314/5879/5718/8945/51606/161/5700/122706/5707/10053/23198/10762/9861/79902/11168/9883/5698/5692/5713/5710/5902/5478/5719/6233/7514/1025/3932/6396/129401/1175/8907/940/60489/1173/4928/5903/55706/7175/4869/5706/160/293/920/5714/4927/5688/5687/5708/5901/8086/5704/7311/8905/5694/1104/5905/3837/81929/164/5684/8065/5720/9631/3159/5690/5717/9491/6500/79023/23636/10197/919/130340/7316/10213/53371/3055/9688/5715/5701/5685/8815/5686/5716/9844/375/5693/5721/8480/291 123 Human_SARS_coronavirus_2 R-HSA-73887 Death Receptor Signalling 133/7348 141/10654 8.204569620540521e-14 1.8711712005555316e-12 8.051343362771513e-13 7124/25999/9639/7984/4790/7531/29/356/7375/55160/9530/8878/1894/23385/10276/4792/8439/84033/100271715/9138/836/23365/10616/26230/57449/3654/8997/26084/8874/121512/1540/3551/64857/7314/5879/257397/9181/81858/8737/8767/55072/2245/84904/23118/841/8517/8887/6453/9828/5970/65078/5664/8797/7128/396/10454/3066/6233/7410/7409/26574/8772/331/128272/8717/25791/8743/55701/5663/84894/445328/56928/572/7204/27237/7074/330/10451/27005/50650/221472/23229/843/22899/8837/11108/8567/7189/6654/4099/7311/387/54848/6655/389337/51107/8795/5924/1147/4804/57142/8841/7186/56957/6885/5584/10018/57580/8793/4974/835/9459/355/11214/23421/23370/4615/9500/7316/4168/23263/50649/9826/7132/329/9099/4803/3065/55512/5599/7185/89846/10672 133 Human_SARS_coronavirus_2 R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic 97/7348 99/10654 9.127403655919706e-14 2.0485950427730893e-12 8.814769111314271e-13 11014/64837/11127/51807/53407/347688/3798/5861/10381/7278/285643/55738/10112/64147/7846/51226/81027/11004/10749/81930/54732/60561/113220/79861/3797/29127/55605/377/1315/3796/124602/11316/55614/89953/56992/8729/23423/10376/1314/3835/147700/3833/378/9493/26286/26958/10959/3831/84364/22820/84617/55850/9585/10382/3832/7277/9554/23303/8775/26153/81876/9183/1062/11015/146909/347733/662/90990/23046/10383/24137/84790/84643/10945/51594/22920/7280/55582/9371/51014/23095/63908/112714/6836/547/8774/10972/381/4905/3834/9276/55083/3799/375/221458/22818/372 97 Human_SARS_coronavirus_2 R-HSA-69052 Switching of origins to a post-replicative state 89/7348 90/10654 1.0672277869229011e-13 2.3536486756519034e-12 1.0127364955905609e-12 8454/5689/9134/11065/5682/7321/8697/143471/5705/5709/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/29882/5001/5696/5691/7314/996/5718/23594/5700/122706/5707/23198/898/890/51433/9861/6502/5698/5692/5713/119504/4175/5710/7324/5719/64682/6233/4999/4172/5000/246184/4173/5706/8881/5714/5688/5687/5708/81620/10393/5704/51343/23595/7311/25906/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 89 Human_SARS_coronavirus_2 R-HSA-416482 G alpha (12/13) signalling events 80/7348 80/10654 1.0819459965868014e-13 2.3536486756519034e-12 1.0127364955905609e-12 2788/9639/7984/29/55160/1894/388/10276/84033/100271715/9138/23365/9475/26230/2768/2782/57449/6093/8997/26084/8874/121512/64857/2787/9181/2245/389/84904/10681/5364/6453/9828/2792/2785/2783/2784/7410/7409/128272/25791/55701/2791/146/445328/148/7204/27237/7074/6915/10451/50650/221472/23229/22899/695/2786/6654/387/54848/6655/389337/147/5924/54331/59345/57580/9459/11214/51764/94235/23370/55970/4168/23263/50649/9826/2793/89846/2790/10672 80 Human_SARS_coronavirus_2 R-HSA-156902 Peptide chain elongation 88/7348 89/10654 1.5362261051990445e-13 3.2421249444051474e-12 1.3950332895601693e-12 6158/6138/6227/6206/6234/6191/6128/6132/6129/1915/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6192/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/140032/6188/200916/6122/6230/6194/6166/1938/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 88 Human_SARS_coronavirus_2 R-HSA-192823 Viral mRNA Translation 88/7348 89/10654 1.5362261051990445e-13 3.2421249444051474e-12 1.3950332895601693e-12 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6192/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/140032/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/5611/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/2926/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 88 Human_SARS_coronavirus_2 R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 87/7348 88/10654 2.2109669733242946e-13 4.5975107357066945e-12 1.9782336077112113e-12 5393/5689/5682/23404/5578/26986/143471/5705/5709/5695/5711/1432/5683/5699/5702/11340/8021/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/7534/9261/8741/9861/5698/5692/5713/1981/5710/5719/6233/5580/7514/5600/8570/23016/118460/1994/5073/3842/3315/5706/8125/677/7538/5714/5688/5687/5708/5704/7311/51010/5694/56915/3304/6418/167227/7529/22894/5684/5720/207/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/55802/51013/5716/54464/5693/54512/5721 87 Human_SARS_coronavirus_2 R-HSA-3700989 Transcriptional Regulation by TP53 311/7348 365/10654 2.8017946089065733e-13 5.741648662309992e-12 2.4705374278382908e-12 6884/6875/834/5563/3725/9134/4436/83990/64769/5892/9156/57060/1763/7531/1459/79370/7486/6874/10971/9997/9212/5982/27327/7295/7533/2810/55367/1460/11200/472/79813/5431/7001/639/5435/5433/1869/28996/84289/1457/6790/6341/25904/29117/4194/4514/1647/5928/1432/1387/4683/10325/56950/51499/2965/8738/5439/192669/1107/8900/6873/5371/8396/2475/672/55571/6881/2967/51616/5518/1386/55835/10670/4513/4343/6117/11198/7159/57472/904/144455/85456/29883/51497/51230/637/64121/83695/7296/7314/5515/27166/23368/9377/23774/6118/2176/1329/3622/7027/2936/51422/7249/404672/79837/898/117584/7534/332/5438/5934/64065/1351/890/983/1643/8797/9656/5519/27154/83860/57459/2821/2177/10000/5985/2877/900/7994/2068/3066/7157/5984/1337/6233/1121/1025/2353/604/839/10419/50484/5600/9167/6883/7936/6829/79733/26523/7874/2744/5608/5884/5810/57521/26155/26013/5875/253260/28956/25920/4512/5170/2963/5434/1820/7862/1029/9219/8445/7532/5436/1345/204851/6878/4869/5931/58528/4850/4292/580/891/84987/80196/54971/4331/641/5111/1108/8148/2966/246175/64223/2962/6119/3364/5571/10524/54457/4848/8812/23019/1616/843/6794/54815/1874/10128/25824/6009/905/1111/2071/55215/8626/208/79109/55004/7311/7161/5562/6880/6908/5983/1340/4697/5564/6882/5565/1020/53615/10397/8795/5432/7248/6877/7529/5516/1017/27161/6917/5440/27165/5305/8621/902/5883/25946/5430/10111/8793/207/22974/57690/835/4849/1027/3486/355/6749/545/5441/8794/192670/153129/8550/7469/9337/7316/6872/2539/1026/54205/5933/5395/6879/9150/5876/143686/10848/5437/1350/9099/8649/51755/2033/995/5728/3065/91875/6827/23112/10498/10542/5527/2968/1349/5932/6834/8851/5300/7156/581/1327/3276/5052/138474/1022/8178/10919/4193 311 Human_SARS_coronavirus_2 R-HSA-5389840 Mitochondrial translation elongation 86/7348 87/10654 3.181539419396585e-13 6.336192590178551e-12 2.7263599472368073e-12 84545/64979/26284/51318/64949/65003/6150/10573/64983/55052/219927/64960/64968/11222/51069/118487/28977/124995/28973/51116/64975/64928/116541/128308/51258/65005/51073/65080/64981/51253/29093/54534/60488/64432/51642/7818/6183/10240/23107/65008/85476/64978/28957/9801/51373/26589/10102/64965/9553/7284/122704/51023/54148/51650/64976/51263/740/54948/55168/64951/63875/92259/54460/55037/29074/51264/6182/29088/65993/56945/57129/79590/116540/28998/63931/64963/10884/64969/51081/5018/78988/55173/90480/51649/54998/51021 86 Human_SARS_coronavirus_2 R-HSA-5419276 Mitochondrial translation termination 86/7348 87/10654 3.181539419396585e-13 6.336192590178551e-12 2.7263599472368073e-12 84545/64979/26284/51318/64949/65003/6150/10573/64983/55052/219927/64960/64968/11222/51069/118487/28977/124995/28973/51116/64975/64928/116541/128308/51258/65005/84340/51073/65080/64981/51253/29093/54534/60488/64432/51642/7818/6183/10240/23107/65008/64978/28957/9801/51373/26589/64965/9553/122704/51023/54148/51650/64976/51263/740/54948/55168/64951/63875/92259/54460/55037/29074/51264/6182/29088/65993/56945/54516/57129/92399/79590/116540/28998/63931/64963/10884/64969/51081/5018/78988/55173/90480/51649/54998/51021 86 Human_SARS_coronavirus_2 R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 85/7348 86/10654 4.57740249683923e-13 8.866365932233795e-12 3.815052117048414e-12 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 85 Human_SARS_coronavirus_2 R-HSA-453276 Regulation of mitotic cell cycle 85/7348 86/10654 4.57740249683923e-13 8.866365932233795e-12 3.815052117048414e-12 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 85 Human_SARS_coronavirus_2 R-HSA-69002 DNA Replication Pre-Initiation 84/7348 85/10654 6.584554500356476e-13 1.2581837923654132e-11 5.413758892184983e-12 5689/5682/143471/5705/5709/5422/1869/4174/5695/84515/4998/5711/10926/5683/990/5699/5702/55388/6117/5001/5558/5696/5691/7314/5718/6118/23594/5700/122706/5707/23198/5557/9861/5698/5692/5713/4175/5710/5719/6233/23649/4999/4172/5000/8318/54107/4173/5706/5714/51053/6119/5688/5687/5427/5708/81620/1870/5704/29935/23595/7311/5694/4176/56655/1017/5684/5720/8317/5690/5717/9491/10197/7316/10213/5426/4171/1871/5715/5701/5685/5686/5716/5693/5721 84 Human_SARS_coronavirus_2 R-HSA-162587 HIV Life Cycle 141/7348 152/10654 7.13011874862964e-13 1.3442650547416412e-11 5.784152472572537e-12 6884/23165/6875/51652/2237/7852/27243/6874/348995/57122/55048/3981/5431/23511/5435/5433/2960/51271/23279/23327/29082/8732/23225/2965/27183/5439/6873/3836/9972/6881/2967/51616/8021/11198/904/51497/55746/92421/7314/137492/25978/51160/2959/7518/404672/10015/91782/5438/3978/10762/79720/51534/9397/79902/11168/9883/89853/83860/51510/2068/5902/5478/6233/7514/1025/6396/129401/6883/7936/6829/2957/25920/4928/2963/5434/5903/55706/7175/79643/5436/6878/920/4331/4927/8148/2966/2962/54457/8812/128866/905/2071/5901/8086/7311/93343/6880/6908/7251/1104/2547/6882/2961/5432/22916/155382/1234/6877/5905/6917/81929/5440/902/9631/3159/5430/5045/7520/6749/79023/5441/23636/7469/4686/7316/6872/53371/9688/8731/6879/9150/9525/2958/5437/8815/6827/2968/138474/1022/8178/8480 141 Human_SARS_coronavirus_2 R-HSA-948021 Transport to the Golgi and subsequent modification 168/7348 185/10654 7.351031092715509e-13 1.3676786796183854e-11 5.884897467575575e-12 9331/6811/23256/374/3972/6711/11014/126003/10960/2153/2530/51807/286/10484/7039/347688/5861/10381/7278/1780/9570/90411/8655/84516/832/3998/55738/7846/1081/51226/9382/375056/9632/3630/81027/6709/51046/79090/10652/54732/51272/51164/9486/58485/1294/79861/9117/10342/128637/2801/377/10466/2517/22872/1315/81562/4247/8615/55014/11316/91949/8729/254263/23423/10376/1314/10540/51332/83696/51128/27095/6399/7109/378/6396/26286/1453/26958/10175/140735/10959/2348/84364/22820/84617/22796/11258/6712/2890/1783/8703/10382/10802/93661/55860/2157/830/7277/4121/10671/9554/966/11196/1639/8702/149111/10282/6710/8775/81876/4124/11015/347733/51143/79748/51693/23243/5537/9871/10383/84790/10945/1075/7280/829/1778/9919/10113/51399/11070/25839/55291/51014/122553/26984/83548/63908/112714/1604/1781/57731/1522/10121/2525/2804/9527/57511/22870/5265/8774/10972/381/6708/4905/11320/89866/2683/9276/287/375/84342/64689/288/10427/10905/22818/372/6480 168 Human_SARS_coronavirus_2 R-HSA-2408557 Selenocysteine synthesis 91/7348 93/10654 7.673762315728899e-13 1.3735063182836281e-11 5.909972842759899e-12 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6192/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/60678/6155/6231/6142/23521/6207/6233/51091/140032/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/22928/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6123/6164/79048/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/118672/6133 91 Human_SARS_coronavirus_2 R-HSA-5368287 Mitochondrial translation 91/7348 93/10654 7.673762315728899e-13 1.3735063182836281e-11 5.909972842759899e-12 84545/64979/26284/51318/64949/65003/6150/10573/64983/55052/219927/64960/64968/11222/51069/118487/28977/124995/28973/51116/64975/64928/116541/128308/51258/65005/84340/51073/65080/64981/51253/29093/54534/60488/64432/4528/51642/7818/6183/10240/23107/65008/85476/64978/28957/219402/9801/51373/26589/10102/64965/9553/7284/122704/51023/54148/51650/64976/51263/740/54948/55168/64951/63875/92259/54460/55037/29074/51264/6182/29088/65993/56945/54516/57129/92399/79590/116540/28998/63931/64963/10884/64969/51081/5018/78988/55173/90480/51649/54998/51021 91 Human_SARS_coronavirus_2 R-HSA-72764 Eukaryotic Translation Termination 91/7348 93/10654 7.673762315728899e-13 1.3735063182836281e-11 5.909972842759899e-12 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/116832/6192/6156/6143/6139/3921/6208/6170/6203/51504/6147/6222/2935/6134/6155/6231/6142/23521/6207/6233/140032/6188/200916/6122/6230/6194/2107/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/23708/9045/6187/6168/6157/6137/6144/9349/4736/327/51121/6159/6217/6152/51065/6141/6123/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 91 Human_SARS_coronavirus_2 R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 102/7348 106/10654 1.462116137174015e-12 2.5842902724550714e-11 1.1119777990612905e-11 374/85439/8674/4738/1212/7039/23208/27348/950/554/10980/22848/7037/3482/408/10987/6456/185/30011/2885/163/11037/23149/9185/7314/9856/1839/161/7018/25977/10618/8027/1856/9892/8322/2060/2069/1601/6453/55707/8301/1129/9146/6455/4074/10920/26119/29979/6233/90019/7474/6844/1213/1211/29924/4036/1175/85021/6869/1173/6857/84251/29988/409/160/338/8218/920/22905/2873/7311/1956/8533/8673/50618/51138/9318/685/127833/1080/29978/58513/7316/1950/64708/3267/3949/867/9341/915/917/6572/115548/1861/143425/3575/6845/551/154/10254/6457/50813 102 Human_SARS_coronavirus_2 R-HSA-5620912 Anchoring of the basal body to the plasma membrane 95/7348 98/10654 1.944760716794476e-12 3.367314802065405e-11 1.4489004359367263e-11 79867/7531/11190/203068/54801/85302/79441/5116/5048/22832/8655/9702/132320/7846/7840/11064/84902/5518/55835/23332/93323/1454/54806/91147/983/79959/10540/117177/57545/26005/54930/54820/23322/1453/9793/4218/11258/22981/8636/54903/80776/7532/55125/10382/121441/7277/9814/23354/146057/9738/1639/55722/4957/5566/7283/22919/27077/22994/4867/1069/5577/10383/5347/80184/22897/5108/261734/57787/10806/9657/1778/115106/22995/55559/10142/51134/95681/1781/80321/8766/79598/10121/347240/84131/3320/79600/10733/4751/80254/26123/9662/55142/8481/51259/55755 95 Human_SARS_coronavirus_2 R-HSA-69206 G1/S Transition 123/7348 131/10654 1.952756815907802e-12 3.367314802065405e-11 1.4489004359367263e-11 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/4998/5711/5928/10926/5683/990/5699/5702/8900/55388/5518/6117/5001/7465/5558/5696/5691/7314/5515/6241/5718/6118/23594/7027/5700/5707/898/5934/5557/993/890/1876/983/9861/5519/6502/5698/10000/5692/5713/595/4175/5710/5719/6233/7298/23649/1719/1163/4999/4172/26271/1019/5000/8318/54107/4173/5706/286826/891/4331/5714/5111/51053/6119/5688/5687/5427/5708/1874/81620/208/5704/29935/23595/7311/5694/4176/5516/56655/1017/5684/5720/902/8317/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1026/5933/5426/4171/5715/5701/5685/5686/3065/5716/1022/5693/5721/7083 123 Human_SARS_coronavirus_2 R-HSA-375276 Peptide ligand-binding receptors 180/7348 201/10654 2.72654833109699e-12 4.644987156832703e-11 1.9986619345263924e-11 729230/4160/10316/2149/23620/7852/1237/4987/51289/2150/3060/3576/6360/4985/2920/3061/2921/1236/554/2831/5367/4988/6370/58191/6755/6866/1524/643/4161/185/339403/64106/2847/2833/6347/187/6750/2587/6387/6368/2922/10663/4889/9283/727/122042/1909/117579/3579/6375/2358/6846/5179/27202/5021/6865/6367/8811/56923/2832/2693/2826/6376/7201/5443/3627/6346/553/257313/59350/3814/51083/2829/1233/6366/2861/728/183/10022/6373/4922/6357/552/4159/2925/2151/6869/2147/50865/10886/2837/10803/57486/351/84432/8484/3062/1907/6351/4158/6863/6752/84539/6753/3577/594857/4157/5368/6754/8862/10911/301/6751/5020/887/4829/186/60675/10563/5540/256933/7200/10850/624/4852/4828/680/5473/4283/1910/6870/128674/885/10874/84634/6356/56477/387129/129521/1234/57007/84109/4923/283869/4986/6374/5539/2852/1230/4886/2919/1908/5196/3827/5173/2357/6352/6348/886/2862/1906/6364/8620/5697/3640/6288/6372/719/6363/2359/347148/5660/1325/1232/4295/551/9002/4887/718/623 180 Human_SARS_coronavirus_2 R-HSA-9609507 Protein localization 149/7348 163/10654 3.9402211576260824e-12 6.632705615337238e-11 2.853944648004857e-11 6804/6811/9218/26063/26519/7321/131118/10965/10901/5621/1384/26520/8504/23600/3313/10005/5009/8239/10440/50/7917/819/3417/390916/51142/25813/23203/9512/23417/4358/80273/3421/5192/225/131474/7314/1891/54677/90639/10952/197257/26061/51608/8528/134266/847/7323/54927/3329/84269/100287932/2053/10469/215/8604/8309/10455/1431/5189/79145/2010/196743/8540/11001/6233/6844/1610/9804/83752/373156/5264/189/3155/10531/5193/51287/30/351/122970/51/55825/10245/91452/8266/7416/4714/293/1678/150274/51024/1962/118424/4580/29090/54363/5830/10651/51179/7311/6342/84896/5195/29928/401505/6449/2395/3295/10063/51268/1528/8310/56942/10452/5827/5824/23480/100188893/51025/7316/400916/10165/7322/56993/3416/5825/26521/100272147/4843/10478/26517/6901/5190/92609/617/54543/5828/224/283927/1537/219743/570/388753/2671/3162/5194/5191/26515/8443/291 149 Human_SARS_coronavirus_2 R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 79/7348 80/10654 4.044816929790455e-12 6.728671927910239e-11 2.8952373813236943e-11 8454/5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 79 Human_SARS_coronavirus_2 R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 86/7348 88/10654 4.491615460050453e-12 7.38505146571086e-11 3.1776667514188026e-11 8454/7531/11190/203068/54801/79441/5116/5048/8655/6790/9702/7846/7840/11064/5518/55835/23332/93323/7314/8945/4659/1454/983/79959/10540/6233/54930/54820/1453/9793/4218/5500/11258/22981/8636/7532/84962/55125/10382/121441/7277/9133/9814/23354/891/9738/1639/55722/4957/5566/7283/22919/22994/79866/1069/5577/7311/10133/10383/5347/80184/22897/5108/4660/10806/1778/115106/22995/55559/10142/95681/6500/1781/7316/80321/10121/84131/23291/3320/10733/4751/80254/9662/55142/8481/55755 86 Human_SARS_coronavirus_2 R-HSA-5663220 RHO GTPases Activate Formins 130/7348 140/10654 4.714834571427515e-12 7.662961016090236e-11 3.2972466815306763e-11 55839/11130/71/6249/9735/5526/51807/9212/347688/388/147841/348995/10381/57122/7278/1780/23122/3688/5048/57405/8655/23279/2491/7846/1060/81027/11004/1855/9184/5518/23332/25909/10726/81930/55746/5879/5515/79682/10403/79861/25936/1856/389/3619/64105/332/5528/6714/79902/3796/1730/5519/81565/91687/11243/10376/23002/83540/1857/7514/54820/29984/1729/5217/6396/64946/9793/140735/220134/84617/4928/5903/55055/80776/1783/401541/10382/79172/7277/79980/6232/5501/54821/9183/1062/699/347733/752/22919/5529/51143/998/286205/10383/5347/387/60/84790/84643/7280/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/6722/8379/23421/79023/55920/112714/1781/4085/5216/81624/55166/51466/79003/5527/701/23380/57551 130 Human_SARS_coronavirus_2 R-HSA-5368286 Mitochondrial translation initiation 85/7348 87/10654 6.390158328815323e-12 1.0267822587437348e-10 4.418075973750308e-11 84545/64979/26284/51318/64949/65003/6150/10573/64983/55052/219927/64960/64968/11222/51069/118487/28977/124995/28973/51116/64975/64928/116541/128308/51258/65005/51073/65080/64981/51253/29093/54534/60488/64432/4528/51642/7818/6183/10240/23107/65008/64978/28957/219402/9801/51373/26589/64965/9553/122704/51023/54148/51650/64976/51263/740/54948/55168/64951/63875/92259/54460/55037/29074/51264/6182/29088/65993/56945/57129/79590/116540/28998/63931/64963/10884/64969/51081/5018/78988/55173/90480/51649/54998/51021 85 Human_SARS_coronavirus_2 R-HSA-163685 Integration of energy metabolism 103/7348 108/10654 7.211610142551946e-12 1.145754690063871e-10 4.9299948697753106e-11 2788/6804/5563/6833/5331/2740/2770/5578/11069/2769/107/3709/3767/9495/2782/3630/2776/79602/8826/5518/31/2181/6513/5515/2787/10411/5567/3745/1131/784/51422/10681/112/5573/5528/111/2792/5519/10554/51085/2785/2783/2784/2771/9370/7086/6844/2182/3710/196883/115/2791/9254/5568/2642/150/113/6616/5566/775/2864/32/23236/6794/6945/2641/2786/5577/3747/773/5207/5565/109/6812/5516/54331/5575/59345/776/51764/94235/114/3708/4082/5330/3790/108/55970/2778/2194/2767/10768/152/2793/5576/783/26251/948/47/5906/51094/9630/2790 103 Human_SARS_coronavirus_2 R-HSA-416476 G alpha (q) signalling events 192/7348 217/10654 7.649130593889694e-12 1.1980703001128453e-10 5.15510037568097e-11 5295/2788/10316/2149/23620/8526/4893/10161/5331/5578/2150/3060/5583/2769/2798/5737/338557/3061/3709/2911/2840/5367/5028/6866/94233/5029/2782/2867/2776/185/2885/11343/6196/64106/2847/8997/9170/6197/3845/6004/3265/8111/1609/2787/6368/2922/1839/5290/1909/6375/23566/2358/7225/1131/6846/5594/27334/10681/5021/6865/2797/56923/2693/7201/2792/553/257313/5598/3814/10800/5588/2863/2785/6195/2783/2784/2829/222545/1241/5332/183/5580/57121/115557/4922/5731/2865/3710/552/2925/2151/6869/2791/2147/10886/2520/2837/146/3357/351/8477/84432/2828/3062/1907/148/7204/6863/84539/594857/6915/10911/301/5032/2642/29933/5020/4935/887/4829/60675/8503/2864/23236/7200/747/624/2641/2796/4828/695/2786/680/6654/9162/1910/6870/128674/885/1956/10874/84634/147/387129/129521/5595/160851/3356/84109/54331/4923/1128/59345/26090/846/3358/1908/51764/94235/3708/5330/3827/55970/57105/1133/3269/2767/886/2862/1906/5031/8620/2793/56413/6288/2869/1385/5997/5296/5581/347148/2846/9630/4295/1902/551/9002/2915/5724/2790/6003/623 192 Human_SARS_coronavirus_2 R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 91/7348 94/10654 7.710353416567816e-12 1.1980703001128453e-10 5.15510037568097e-11 114791/10844/440145/7531/11190/203068/54801/51807/347688/79441/10381/5116/7278/5048/8655/9702/7846/7840/11064/81027/5518/55835/29922/23332/93323/79861/1454/983/79959/80097/10376/10540/85378/54930/54820/1453/27229/9793/84617/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/9738/1639/55722/4957/5566/7283/347733/22919/10426/22994/1069/5577/10383/5347/84790/80184/22897/5108/7280/10806/1778/115106/4926/22995/55559/10142/95681/112714/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 91 Human_SARS_coronavirus_2 R-HSA-74752 Signaling by Insulin receptor 77/7348 78/10654 8.34983304914604e-12 1.2833330360317936e-10 5.5219719707167185e-11 5295/3643/4893/2250/5291/535/50617/10312/9965/2264/3630/2885/8660/9846/2252/534/2253/3845/3265/54106/51606/5290/3667/8823/526/537/155066/9550/9114/5594/8074/57761/2260/525/2249/2248/2247/529/533/2246/2251/117145/523/528/5781/30849/5170/6464/2322/5140/527/2263/208/9365/6654/2549/5595/8822/8817/2254/152831/127124/5289/26281/10818/23545/2261/90423/245972/2255/8992/27006/5296/245973/51382/9296/2887 77 Human_SARS_coronavirus_2 R-HSA-2500257 Resolution of Sister Chromatid Cohesion 118/7348 126/10654 9.348654827372173e-12 1.4213976264413176e-10 6.116041301891472e-11 55839/11130/6249/9735/5526/51807/9212/347688/10274/147841/348995/10381/57122/7278/1780/23122/5048/57405/8655/23279/2491/7846/1060/81027/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/79861/25936/55869/3619/64105/332/5528/983/79902/3796/5519/81565/91687/11243/10376/83540/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/55055/80776/1783/401541/10382/79172/7277/9133/79980/6232/23047/5885/891/5501/54821/9183/1062/699/347733/22919/8243/5529/51143/10383/5347/84790/84643/7280/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23244/23421/79023/55920/10735/112714/1781/4085/55166/79003/9126/5527/701/57551 118 Human_SARS_coronavirus_2 R-HSA-204005 COPII-mediated vesicle transport 68/7348 68/10654 9.697112039832573e-12 1.458693236630134e-10 6.276518207192864e-11 6811/23256/374/126003/10960/2153/10484/7039/5861/9570/90411/3998/9632/79090/10652/58485/1294/9117/10342/128637/2801/22872/81562/8615/55014/254263/83696/51128/27095/6399/7109/6396/1453/10175/10959/2348/2890/10802/2157/9554/966/11196/149111/10282/8775/81876/79748/51693/23243/5537/9871/1075/9919/10113/51399/55291/122553/26984/63908/1522/22870/5265/8774/10972/4905/89866/64689/10427 68 Human_SARS_coronavirus_2 R-HSA-4086400 PCP/CE pathway 89/7348 92/10654 1.531860997256102e-11 2.2800541580211876e-10 9.810699794061242e-11 5689/5579/5682/1212/5578/81029/5582/143471/5705/5709/5695/5881/5711/5683/5699/5702/57216/1855/163/5696/5691/4920/7314/5879/5718/2535/161/5700/122706/5707/1856/8322/23198/7471/8323/9861/8321/7481/5698/5880/5692/5713/23002/5710/5719/6233/7474/1857/1213/1211/7855/1175/7976/1173/144165/409/5706/160/5714/5688/5687/4919/5708/5704/7311/387/5694/57154/5684/5720/5690/5717/9491/50855/10197/64750/7316/10213/54361/5216/5715/5701/5685/5686/23513/5716/5693/5721/6259 89 Human_SARS_coronavirus_2 R-HSA-69618 Mitotic Spindle Checkpoint 106/7348 112/10654 1.6016392055162725e-11 2.3590810797916765e-10 1.0150739701627255e-10 55839/11130/11065/6249/9735/7321/5526/8697/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/996/5515/79682/10403/25936/3619/64105/332/5528/51433/79902/3796/5519/81565/91687/119504/11243/7324/83540/64682/7514/54820/6396/64946/9793/140735/220134/4928/5903/246184/55055/80776/1783/401541/79172/79980/6232/8881/5501/54821/9183/1062/699/22919/5529/51143/10393/25906/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/79023/55920/1781/4085/55166/79003/5527/701/57551 106 Human_SARS_coronavirus_2 R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 75/7348 76/10654 1.722312896990155e-11 2.5106705529320405e-10 1.0803004389151489e-10 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 75 Human_SARS_coronavirus_2 R-HSA-2132295 MHC class II antigen presentation 115/7348 123/10654 2.3766124793034546e-11 3.429112291566413e-10 1.475490884035872e-10 64837/162/11127/51807/10484/1174/347688/3798/1785/10381/7278/1780/3115/1509/8655/84516/3109/832/285643/3113/10112/972/7846/5476/3117/9632/81027/6456/11004/3112/163/1759/3127/81930/51164/161/79861/3797/10053/29127/3126/1515/22872/3111/3796/10437/89953/56992/83547/10376/10540/3835/147700/51128/1213/1211/9493/6396/1175/7879/140735/8907/1508/1514/3831/3120/1173/84617/11258/6712/1783/10382/10802/93661/821/55860/830/3123/3832/7277/160/10671/3122/1639/26052/26153/1062/347733/51143/9871/10383/24137/84790/84643/8905/3125/22920/1075/7280/829/1778/114876/164/9371/3119/10120/112714/130340/1512/1781/10121/1520/3799/375/10427 115 Human_SARS_coronavirus_2 R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 74/7348 75/10654 2.47283773092674e-11 3.5319116682125356e-10 1.5197237729672045e-10 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 74 Human_SARS_coronavirus_2 R-HSA-8873719 RAB geranylgeranylation 65/7348 65/10654 2.9807955682717035e-11 4.214844933536189e-10 1.8135787773274155e-10 5869/116442/1122/10981/5861/23011/51762/376267/51552/9230/83452/27314/10966/201475/5874/339122/8073/5868/55647/51209/326624/5872/9545/57111/347517/5870/1121/23682/4218/401258/142684/7879/5875/51715/25837/115827/401409/9363/5864/57799/53917/57403/81876/8934/5867/54734/115273/83871/53916/22931/9609/64284/10890/84932/5862/8766/9367/5876/51560/11021/5873/5878/11031/5865/338382 65 Human_SARS_coronavirus_2 R-HSA-162599 Late Phase of HIV Life Cycle 128/7348 139/10654 3.49374984229263e-11 4.891249779209682e-10 2.1046247095832625e-10 6884/23165/6875/51652/27243/6874/348995/57122/55048/5431/23511/5435/5433/2960/51271/23279/23327/29082/8732/23225/2965/27183/5439/6873/9972/6881/2967/51616/8021/11198/904/51497/55746/92421/7314/137492/25978/51160/2959/404672/10015/91782/5438/10762/79720/51534/9397/79902/9883/89853/83860/51510/2068/5902/5478/6233/7514/1025/6396/129401/6883/7936/6829/2957/25920/4928/2963/5434/5903/55706/7175/79643/5436/6878/4331/4927/8148/2966/2962/54457/8812/128866/905/2071/5901/8086/7311/93343/6880/6908/7251/1104/6882/2961/5432/22916/155382/6877/5905/6917/81929/5440/902/9631/5430/5045/6749/79023/5441/23636/7469/4686/7316/6872/53371/9688/8731/6879/9150/9525/2958/5437/6827/2968/138474/1022/8178/8480 128 Human_SARS_coronavirus_2 R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 80/7348 82/10654 3.707439060743996e-11 5.089629933875738e-10 2.1899844426264996e-10 114791/10844/440145/7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/1454/983/79959/80097/10540/85378/54930/54820/1453/27229/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/728642/9738/1639/55722/4957/5566/7283/22919/984/10426/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 80 Human_SARS_coronavirus_2 R-HSA-380287 Centrosome maturation 80/7348 82/10654 3.707439060743996e-11 5.089629933875738e-10 2.1899844426264996e-10 114791/10844/440145/7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/1454/983/79959/80097/10540/85378/54930/54820/1453/27229/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/728642/9738/1639/55722/4957/5566/7283/22919/984/10426/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 80 Human_SARS_coronavirus_2 R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72/7348 73/10654 5.094321890370509e-11 6.926318416330674e-10 2.980281429791654e-10 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/5716/701/5693/5721 72 Human_SARS_coronavirus_2 R-HSA-391251 Protein folding 96/7348 101/10654 7.145545691671012e-11 9.482275683993181e-10 4.080068000705769e-10 2788/2780/9134/1459/2770/51807/10528/1460/10381/7278/2775/10576/1457/7846/7411/2782/81027/10574/6468/10564/54461/10693/8877/2773/5201/2787/402/79861/5204/10575/6903/10681/898/10517/2792/10471/26985/2785/10376/2783/26190/2784/10238/7157/2771/83752/2791/6904/5202/26224/84617/2629/2781/8237/10382/7277/63971/6774/26272/26270/347733/5082/2786/10383/60/84790/22948/7280/84261/9628/10694/8841/54331/22803/59345/8787/5203/51764/94235/2779/112714/7203/908/55970/6902/6905/346562/11328/1155/2793/6950/3801/55294/6499/26234/2790 96 Human_SARS_coronavirus_2 R-HSA-5607764 CLEC7A (Dectin-1) signaling 96/7348 101/10654 7.145545691671012e-11 9.482275683993181e-10 4.080068000705769e-10 8454/5689/4790/5682/7321/9039/29108/143471/5705/5530/5709/5695/4792/3709/5711/5683/5699/5702/64170/7334/3551/5696/5691/7314/257397/5718/8945/4773/5700/122706/5707/5336/23198/23118/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/3710/801/4791/805/5170/387522/4772/4775/5706/6850/8915/5714/5688/5687/5708/7189/5704/7311/5971/5694/997/1147/5684/5720/6885/5690/3553/5532/5717/9491/6500/3708/10197/7316/10213/7335/10768/7322/5715/5701/23291/5685/5686/5716/808/5693/5721 96 Human_SARS_coronavirus_2 R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 71/7348 72/10654 7.309533589499694e-11 9.482275683993181e-10 4.080068000705769e-10 5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 71 Human_SARS_coronavirus_2 R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 71/7348 72/10654 7.309533589499694e-11 9.482275683993181e-10 4.080068000705769e-10 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 71 Human_SARS_coronavirus_2 R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 71/7348 72/10654 7.309533589499694e-11 9.482275683993181e-10 4.080068000705769e-10 5689/9134/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/990/5699/5702/8900/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/898/890/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/1017/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 71 Human_SARS_coronavirus_2 R-HSA-202403 TCR signaling 111/7348 119/10654 8.179160031936782e-11 1.0440905908597602e-9 4.492550893448532e-10 5295/8454/5689/5335/4790/5682/5291/7321/143471/5705/5788/3115/5709/5695/4792/3113/5711/3117/5683/55824/5699/5702/26191/3127/7334/3551/5062/5696/5691/7314/5718/8945/3635/5290/5700/122706/5707/8767/23198/23118/8517/3126/5970/9861/5588/5698/5692/5713/1445/5710/916/5719/6233/3702/3932/3120/5170/387522/3937/3123/5706/3122/920/8915/5714/5795/5688/5687/5708/5063/7189/7535/5704/7311/3125/5694/5058/997/1147/55740/9402/5684/5720/6885/4690/3119/5690/5717/9491/6500/10197/919/7316/10213/7335/7322/5715/5701/23291/915/5685/917/51466/5686/7408/5728/7454/5716/5296/5693/5721 111 Human_SARS_coronavirus_2 R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 90/7348 94/10654 8.196184977753421e-11 1.0440905908597602e-9 4.492550893448532e-10 8454/3725/9252/4790/7321/1848/4792/177/1432/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/23098/11035/8945/1326/5601/5606/8737/8767/1849/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5608/4791/3665/351/387522/330/7098/79155/7867/64127/5602/3656/7189/7311/9641/6416/28511/5595/5516/1147/1845/6885/5604/10392/6500/7316/7335/4205/4793/3146/7322/329/466/23291/6288/6285/5609/1385/5599/148022 90 Human_SARS_coronavirus_2 R-HSA-611105 Respiratory electron transport 95/7348 100/10654 9.895495375896471e-11 1.2493062912069294e-9 5.375560457958798e-10 4723/2110/4719/9997/4724/6389/4715/4538/6341/4514/4695/4540/4696/4705/7384/137682/4513/4720/79133/51079/9377/1329/4702/7388/55863/4519/1351/4536/6390/4725/10975/4541/10131/4731/4707/55967/1337/4716/126328/9167/93058/4512/6391/6392/4700/4711/4712/1345/55471/4710/51295/7386/4714/84987/4701/10128/27089/2108/7381/4726/4708/1340/4713/4697/4709/91942/51300/4722/4717/29796/4535/29078/4704/2109/51103/4729/4718/54205/7385/80219/4728/374291/1350/25915/1349/4706/28976/6834/54539/4698/1327/4537/1537/4694/80224 95 Human_SARS_coronavirus_2 R-HSA-6802957 Oncogenic MAPK signaling 70/7348 71/10654 1.048565280000654e-10 1.3005888648429165e-9 5.596220977288809e-10 4893/71/817/5908/55109/54845/8546/22866/5605/5037/3717/10827/2244/3690/408/4296/5894/8826/1185/4140/3845/3265/4763/818/8805/55750/8844/7094/5594/7414/10533/23164/57085/6714/9061/2335/1445/2266/2243/369/801/57670/805/283455/3674/409/673/8315/816/56829/7450/60/9444/7529/5595/4000/27044/815/22906/8087/5604/10018/10142/54518/80853/10256/5906/808/9715/5245 70 Human_SARS_coronavirus_2 R-HSA-68949 Orc1 removal from chromatin 70/7348 71/10654 1.048565280000654e-10 1.3005888648429165e-9 5.596220977288809e-10 8454/5689/5682/143471/5705/5709/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/890/9861/6502/5698/5692/5713/4175/5710/5719/6233/4999/4172/5000/4173/5706/5714/5688/5687/5708/81620/5704/23595/7311/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 70 Human_SARS_coronavirus_2 R-HSA-166166 MyD88-independent TLR4 cascade 94/7348 99/10654 1.369640804738125e-10 1.6695449119825077e-9 7.183778449533905e-10 8454/3725/9252/4790/7321/1848/4792/177/1432/929/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/23098/11035/8945/1326/5601/5606/8737/8767/1849/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/3665/351/387522/330/79155/7867/64127/5602/3656/7189/7311/9641/6416/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/7316/7335/4205/4793/3146/7322/329/466/23291/6288/6285/5609/1385/5599/353376/148022 94 Human_SARS_coronavirus_2 R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 94/7348 99/10654 1.369640804738125e-10 1.6695449119825077e-9 7.183778449533905e-10 8454/3725/9252/4790/7321/1848/4792/177/1432/929/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/23098/11035/8945/1326/5601/5606/8737/8767/1849/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/3665/351/387522/330/79155/7867/64127/5602/3656/7189/7311/9641/6416/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/7316/7335/4205/4793/3146/7322/329/466/23291/6288/6285/5609/1385/5599/353376/148022 94 Human_SARS_coronavirus_2 R-HSA-5357801 Programmed Cell Death 161/7348 181/10654 1.456074132015899e-10 1.7597340364704965e-9 7.571847488125862e-10 5689/5682/4976/7531/55075/356/10971/51074/10059/7533/2810/143471/5705/5709/1869/5695/8655/5711/90249/836/5683/929/324/5699/9414/5702/90427/4001/3836/6709/6093/840/7159/26060/637/5062/5696/5691/7314/578/23368/5718/2934/11035/22985/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/100506658/7082/5339/5317/8797/9861/28988/10134/22900/999/5588/598/5698/10000/5692/708/5713/5710/3002/7157/5719/6233/5580/1613/839/8772/331/8717/57099/8743/140735/1828/5747/1029/572/7532/330/118/5706/1829/6774/5714/8428/5688/5687/1832/56616/5708/8837/8626/1830/197259/208/5704/7311/7161/5694/8795/3148/7529/5595/23643/4000/5533/3837/1676/596/5684/5720/7186/51765/1499/10018/842/207/5690/5717/9491/355/10197/7099/9500/7316/10213/54205/115209/3146/5715/79658/5701/329/5685/5686/4137/5716/1677/1630/581/5599/353376/7431/5693/5721/6304/148022 161 Human_SARS_coronavirus_2 R-HSA-2682334 EPH-Ephrin signaling 88/7348 92/10654 1.5931934631300206e-10 1.9091318278524142e-9 8.214681727824728e-10 71/2042/1947/1212/23385/2051/2045/10094/2050/285220/79784/2047/2534/9475/1948/4628/8976/6093/163/8997/1759/8440/8874/3265/5062/5879/1072/161/10093/5921/2046/6453/4313/2902/2041/102/6714/5664/1943/2043/7525/1942/7410/1213/1211/1175/25791/10109/5663/64283/1173/2904/5747/7074/1949/10627/1945/10451/4318/160/2049/8218/10092/4067/2044/5063/6386/998/2048/10097/387/60/51107/5058/4629/3984/28964/4627/3985/6383/10398/10552/4637/1946/10096/103910/10095/1969 88 Human_SARS_coronavirus_2 R-HSA-216083 Integrin cell surface interactions 82/7348 85/10654 1.6720932706737964e-10 1.986840239271217e-9 8.549048301189336e-10 3675/8174/3681/960/3696/5175/256076/3383/1280/1289/7448/6696/1300/3688/3693/3381/1290/2244/3690/3694/2200/3679/1285/22801/1296/1311/3655/1294/375790/7412/1284/1305/1307/50848/3683/3672/1298/999/2335/1295/1288/2266/3685/1292/2243/3791/1293/1291/1286/1287/91522/3674/3684/3384/83700/3678/1277/3695/4060/7450/8515/3676/3371/1282/1299/3339/1281/1297/3673/682/8516/50509/3687/3680/131873/80781/7057/1278/3689/961/58494/3682 82 Human_SARS_coronavirus_2 R-HSA-202424 Downstream TCR signaling 93/7348 98/10654 1.8946916613771615e-10 2.232578340989422e-9 9.606419125228065e-10 5295/8454/5689/4790/5682/5291/7321/143471/5705/3115/5709/5695/4792/3113/5711/3117/5683/5699/5702/3127/7334/3551/5696/5691/7314/5718/8945/3635/5290/5700/122706/5707/8767/23198/23118/8517/3126/5970/9861/5588/5698/5692/5713/5710/916/5719/6233/3932/3120/5170/387522/3123/5706/3122/920/8915/5714/5688/5687/5708/7189/5704/7311/3125/5694/997/1147/5684/5720/6885/3119/5690/5717/9491/6500/10197/919/7316/10213/7335/7322/5715/5701/23291/915/5685/917/5686/5728/5716/5296/5693/5721 93 Human_SARS_coronavirus_2 R-HSA-418594 G alpha (i) signalling events 335/7348 406/10654 1.925807292547176e-10 2.250488852612981e-9 9.68348512476962e-10 2788/729230/10316/2780/1880/5158/7852/50833/29899/6385/5331/5726/338442/64805/2770/817/1237/1258/2550/5578/50832/3354/2841/5582/4987/51289/259294/2912/3576/6360/2775/5530/4985/2920/2921/1236/259295/107/6010/9568/3709/2840/2831/5367/4988/6370/58191/157506/2774/5475/6755/1524/643/221914/2782/5499/339403/4023/2914/8843/2847/2833/10636/9290/5518/9170/6382/187/5143/221391/6750/6004/259296/259289/50835/2587/53829/2773/5515/2787/6387/6368/818/4544/5947/4543/126006/10663/4889/9283/727/338398/344/117579/3579/84152/345/375790/23566/2358/5567/2916/259293/5594/5179/10681/5142/112/8811/5573/348/56923/2832/5528/27199/2826/6376/165140/27198/111/5443/85397/3627/2792/9397/54429/6714/336/3361/6346/10988/5519/134/5588/6295/1129/338328/51083/2785/2783/2784/1233/2262/6366/5613/2861/2771/728/5332/183/10022/5580/23173/6373/57121/3710/1132/1814/80835/4036/6357/196883/9672/115/8698/801/9934/50840/2791/23596/50865/805/10803/2913/5145/3838/7276/351/11251/3352/8484/6351/6752/2781/1903/84539/6753/5568/3577/2918/5368/6754/8862/301/56670/150/113/338/2868/2342/335/2853/6751/186/53637/10645/5566/10563/5540/1901/5148/5733/23236/256933/10850/624/4852/816/8601/2786/5995/6001/50838/5577/5473/4283/2239/11255/10874/83756/51109/611/2719/56477/1020/5141/259286/3350/129521/1234/109/10692/9628/5516/151/57007/5533/815/26086/5321/9294/54331/283869/2817/5575/59345/63940/4986/8787/6374/5539/259287/2852/50836/3339/1230/5532/846/4886/2919/51764/94235/114/3708/5330/259290/57016/6383/108/5196/2779/3827/5173/2357/55970/2778/6352/140/10768/346562/152/55937/6364/80834/259292/3949/2793/5030/5697/5576/53630/3355/3351/4035/6288/6372/50834/259285/79823/1385/7804/5144/719/6363/2917/1268/50831/2359/50839/808/388531/5660/1815/1325/1232/1902/10082/50837/1269/59340/4887/2790/718/6003/623 335 Human_SARS_coronavirus_2 R-HSA-446203 Asparagine N-linked glycosylation 257/7348 304/10654 2.0031330206432597e-10 2.321664009171778e-9 9.989740171974153e-10 9331/6811/23256/374/3972/4759/6711/11014/126003/10960/2153/2673/256435/5373/2530/9761/51807/79053/286/10484/7039/6482/347688/10195/5861/54187/811/10381/9945/7278/1780/9570/90411/8655/84516/832/3998/55738/7846/5476/1081/6400/51226/9382/375056/9632/3630/81027/55907/7991/6709/85365/51009/433/51046/2720/79087/79090/8818/10652/54732/51272/4758/7314/51164/9486/58485/1294/5238/79861/9117/10342/9695/5700/10956/79139/128637/2801/91445/84920/9526/6184/10825/377/55577/10466/2517/56052/22872/1798/1315/81562/10559/4247/11253/8615/55014/11316/80267/91949/8729/254263/23423/10376/144245/22845/1603/1314/10540/6185/6233/55741/51332/83696/79947/51128/27095/6399/7109/23193/378/6396/129807/26286/1453/54344/8813/267/26958/10175/140735/10959/64772/2348/84364/22820/84617/7841/22796/11258/6712/79796/2890/1783/8703/10020/1650/29880/6048/10382/10802/93661/821/55860/2157/830/7277/55757/4121/56886/10671/9554/10206/84447/7264/966/84061/11196/1639/8702/149111/10282/6710/8775/81876/4124/6675/11015/347733/79868/2923/51143/79748/51693/23243/5537/7311/9871/10383/84790/55768/10945/91869/1075/7280/829/1778/9919/10113/51399/11070/199857/440138/25839/55291/51014/57171/122553/7844/26984/83548/63908/112714/1604/282969/1781/7316/140838/5589/57731/116150/1522/10121/7415/2525/2804/9527/57511/22870/5265/8774/29925/10972/51035/381/6708/4905/27090/11320/89866/2683/11236/9276/287/2762/3703/5887/375/84342/64689/29929/288/10427/10905/22818/372/6480 257 Human_SARS_coronavirus_2 R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 75/7348 77/10654 2.1334155437931728e-10 2.452560633271176e-9 1.0552966917522072e-9 5689/5682/51807/63943/347688/143471/10381/5705/7278/5709/5695/5711/7846/5683/5699/5702/81027/5696/5691/7314/5718/79861/5700/122706/5707/23198/983/9861/5698/5692/5713/10376/5710/7157/5719/6233/84617/51512/10382/7277/5706/9133/891/5714/5688/5687/347733/5708/22919/5704/3326/7311/10383/5347/84790/5694/7280/5684/5720/5690/5717/9491/10197/112714/7316/10213/1026/5715/5701/5685/3320/5686/5716/5693/5721 75 Human_SARS_coronavirus_2 R-HSA-72202 Transport of Mature Transcript to Cytoplasm 81/7348 84/10654 2.3486086218779657e-10 2.6781714446253573e-9 1.1523733305988661e-9 23165/8683/6431/84271/199746/348995/57122/23511/81608/65109/23279/728343/23225/9877/9972/8021/55746/7919/53981/6432/8563/6430/56001/80145/10762/22794/9785/11338/29107/4116/79902/9883/51213/10250/26097/51362/1977/57187/6396/129401/79228/2733/84324/4928/5903/55706/7175/7884/6428/10212/55110/84321/6429/4927/10898/10569/9295/10482/51692/8086/9939/6426/22916/10921/81929/9631/29894/79023/23636/4686/8189/53371/7307/9688/9984/10189/9775/84248/6427/8480/55339 81 Human_SARS_coronavirus_2 R-HSA-193704 p75 NTR receptor-mediated signalling 92/7348 97/10654 2.6195620379963483e-10 2.963248577381469e-9 1.27503735407317e-9 9639/7984/4790/7531/29/55160/8878/1894/23385/10276/4792/84033/100271715/9138/836/23365/26230/57449/3654/8997/26084/8874/121512/3551/64857/7314/5879/9181/8767/2245/84904/6453/9828/5970/65078/5664/396/3066/6233/7410/7409/26574/128272/25791/55701/5663/84894/445328/572/7204/27237/7074/10451/50650/221472/23229/22899/11108/7189/6654/4099/7311/387/54848/6655/389337/51107/5924/4804/57142/8841/5584/10018/57580/4974/835/9459/11214/23421/23370/4615/9500/7316/4168/23263/50649/9826/4803/3065/5599/89846/10672 92 Human_SARS_coronavirus_2 R-HSA-193648 NRAGE signals death through JNK 59/7348 59/10654 2.8132559766032857e-10 3.132239331430745e-9 1.347751309139411e-9 9639/7984/29/55160/1894/10276/84033/100271715/9138/23365/26230/57449/8997/26084/8874/121512/64857/5879/9181/2245/84904/6453/9828/7410/7409/26574/128272/25791/55701/445328/572/7204/27237/7074/10451/50650/221472/23229/22899/6654/54848/6655/389337/5924/4804/10018/57580/9459/11214/23370/9500/4168/23263/50649/9826/4803/5599/89846/10672 59 Human_SARS_coronavirus_2 R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 59/7348 59/10654 2.8132559766032857e-10 3.132239331430745e-9 1.347751309139411e-9 6227/6206/1965/6234/27335/6191/8668/6224/8662/26986/6202/6218/6192/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/140032/51386/6188/1978/1968/6230/8669/6194/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 59 Human_SARS_coronavirus_2 R-HSA-68867 Assembly of the pre-replicative complex 67/7348 68/10654 3.091049356149793e-10 3.414643585621724e-9 1.4692652367225168e-9 5689/5682/143471/5705/5709/1869/4174/5695/84515/4998/5711/5683/990/5699/5702/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/9861/5698/5692/5713/4175/5710/5719/6233/4999/4172/5000/4173/5706/5714/51053/5688/5687/5708/81620/1870/5704/23595/7311/5694/4176/5684/5720/5690/5717/9491/10197/7316/10213/4171/1871/5715/5701/5685/5686/5716/5693/5721 67 Human_SARS_coronavirus_2 R-HSA-109581 Apoptosis 158/7348 178/10654 3.185072245008796e-10 3.4912342282499515e-9 1.5022209364464173e-9 5689/5682/4976/7531/55075/356/10971/51074/10059/7533/2810/143471/5705/5709/1869/5695/8655/5711/90249/836/5683/929/324/5699/9414/5702/90427/4001/3836/6709/6093/840/7159/26060/637/5062/5696/5691/7314/578/23368/5718/2934/22985/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/100506658/7082/5339/5317/8797/9861/28988/10134/22900/999/5588/598/5698/10000/5692/708/5713/5710/3002/7157/5719/6233/5580/1613/839/8772/331/8717/57099/8743/140735/1828/5747/1029/572/7532/118/5706/1829/6774/5714/8428/5688/5687/1832/56616/5708/8837/8626/1830/208/5704/7311/7161/5694/8795/3148/7529/5595/23643/4000/5533/3837/1676/596/5684/5720/7186/51765/1499/10018/842/207/5690/5717/9491/355/10197/7099/9500/7316/10213/54205/115209/3146/5715/79658/5701/329/5685/5686/4137/5716/1677/1630/581/5599/353376/7431/5693/5721/6304/148022 158 Human_SARS_coronavirus_2 R-HSA-72649 Translation initiation complex formation 58/7348 58/10654 4.089061773400327e-10 4.413689578311498e-9 1.899138372860899e-9 6227/6206/1965/6234/27335/6191/8668/6224/8662/26986/6202/6218/6192/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/140032/51386/6188/1968/6230/8669/6194/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 58 Human_SARS_coronavirus_2 R-HSA-72702 Ribosomal scanning and start codon recognition 58/7348 58/10654 4.089061773400327e-10 4.413689578311498e-9 1.899138372860899e-9 6227/6206/1965/6234/27335/6191/8668/6224/8662/6202/6218/6192/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/140032/51386/6188/1968/6230/8669/6194/1983/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 58 Human_SARS_coronavirus_2 R-HSA-194315 Signaling by Rho GTPases 371/7348 455/10654 4.182627159032095e-10 4.480480911266199e-9 1.9278775900482866e-009 57569/55839/9639/11130/7984/394/398/64837/71/6249/51517/5579/57522/392/9735/7531/55789/5526/29/51807/2909/10811/10971/5578/9212/55160/347688/613/3798/1894/388/7533/2810/147841/348995/116985/54509/10381/57122/10276/6280/7278/1780/23122/3688/5048/57405/8655/10094/84033/23279/10144/5881/1432/2017/100271715/2491/9138/143872/7846/115703/23365/23081/79784/9475/1060/171177/26230/9322/397/81027/4628/57449/51291/11004/8976/1855/2885/23433/6093/9184/8997/8826/10499/5518/26084/8874/121512/23332/25909/64857/10726/81930/5062/55746/9411/2665/5879/10395/5515/9181/85415/26999/25/79682/64333/1072/10403/79861/55843/4638/25936/4659/10093/1856/10006/9938/257106/4771/2245/389/5594/29127/84904/3619/64105/89839/1124/7534/94274/332/84144/5528/6453/9828/6714/55114/79902/3796/1730/5519/81565/57636/999/89953/396/10810/5880/85360/91687/158763/11243/10376/23002/57584/11113/58504/83540/7410/5580/7409/1857/9055/128239/4649/23191/7514/51306/147700/54820/29984/1729/114822/5217/6396/1535/128272/5600/91614/25791/801/64946/9793/55701/30849/10109/5586/140735/9886/2664/5500/80728/10787/4221/805/3831/220134/5170/84617/4928/4688/9743/445328/5590/5903/9912/653361/55055/5747/80776/1783/401541/7204/64411/2316/7532/3633/27237/10382/7074/10627/79172/7277/10451/79980/58480/6232/117289/5501/50650/9754/221472/10152/6279/23229/393/55288/54821/10092/9183/4650/1062/699/94134/22899/347733/752/22919/5063/3895/57514/5529/51143/998/695/286205/6654/10097/3817/57120/367/57381/10383/5347/387/54848/6655/60/84790/84643/389337/5058/5924/4660/93663/7280/4629/7529/5595/64130/1778/5516/5905/81929/3984/54908/55143/1495/1499/5525/4690/1058/991/79019/57580/4627/10928/348235/80152/10458/1063/3985/54763/6722/8379/1027/9459/11214/1080/23421/79023/55920/23370/30851/116984/112714/6242/1781/9824/10398/4085/5289/5585/5216/4168/10552/81624/23263/55166/50649/79658/9826/8936/23092/4637/1123/51466/995/79003/391/23221/23028/89941/2/1742/90627/5527/83478/10096/7454/701/23380/9928/29941/3799/103910/57551/5296/5300/84986/808/10095/1536/395/201176/89846/399/4952/4983/9901/10672 371 Human_SARS_coronavirus_2 R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 66/7348 67/10654 4.4299545416468416e-10 4.67459382230495e-9 2.0114011980140414e-9 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 66 Human_SARS_coronavirus_2 R-HSA-6802952 Signaling by BRAF and RAF fusions 66/7348 67/10654 4.4299545416468416e-10 4.67459382230495e-9 2.0114011980140414e-9 4893/71/817/5908/55109/54845/8546/22866/5605/5037/3717/10827/2244/3690/408/5894/8826/1185/4140/3845/3265/818/8805/55750/8844/7094/5594/7414/10533/23164/57085/6714/9061/2335/1445/2266/2243/369/801/57670/805/283455/3674/409/673/816/56829/7450/60/9444/7529/5595/4000/27044/815/22906/8087/5604/10018/10142/54518/80853/10256/5906/808/9715 66 Human_SARS_coronavirus_2 R-HSA-195253 Degradation of beta-catenin by the destruction complex 79/7348 82/10654 4.627172349799239e-10 4.846534594530463e-9 2.085384497609326e-9 8454/5689/5682/5526/1452/143471/5705/5709/9978/5695/5711/5683/324/5699/8312/5702/6932/5518/5696/5691/7314/5515/5718/51176/8945/5700/122706/5707/23198/5528/7091/83439/9861/5519/2932/5698/5692/5713/5710/5719/6233/7089/7090/10023/5706/5714/6934/5688/5687/5708/5529/7088/5704/7311/5694/5516/5684/5720/1487/1499/5525/139285/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/3065/5527/1488/5716/5693/5721 79 Human_SARS_coronavirus_2 R-HSA-390466 Chaperonin-mediated protein folding 90/7348 95/10654 4.998796469092068e-10 5.197278093600135e-9 2.2363036835411884e-9 2788/2780/9134/1459/2770/51807/10528/1460/10381/7278/2775/10576/1457/7846/7411/2782/81027/10574/6468/10564/54461/10693/8877/2773/5201/2787/79861/5204/10575/10681/898/10517/2792/10471/26985/2785/10376/2783/26190/2784/10238/7157/2771/83752/2791/5202/26224/84617/2629/2781/8237/10382/7277/63971/6774/26272/26270/347733/5082/2786/10383/60/84790/22948/7280/84261/9628/10694/8841/54331/22803/59345/8787/5203/51764/94235/2779/112714/7203/908/55970/346562/11328/2793/6950/3801/55294/6499/26234/2790 90 Human_SARS_coronavirus_2 R-HSA-8854518 AURKA Activation by TPX2 71/7348 73/10654 8.594954890858211e-10 8.850485315366146e-9 3.8082189475780784e-9 7531/11190/203068/54801/79441/5116/5048/8655/6790/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/22974/3161/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 71 Human_SARS_coronavirus_2 R-HSA-432722 Golgi Associated Vesicle Biogenesis 56/7348 56/10654 8.637673080060312e-10 8.850485315366146e-9 3.8082189475780784e-9 27131/162/1176/5286/1174/1785/8546/7037/3482/408/6456/7164/3312/1362/26258/25977/10618/6643/10053/55330/8301/2495/388552/152503/6844/54885/1213/2580/1211/23431/8907/84062/9685/9026/8775/9829/8905/51429/64746/8673/23557/2512/164/130340/6272/2804/2647/7163/286451/9698/5878/81567/10717/6845/375/4952 56 Human_SARS_coronavirus_2 R-HSA-76002 Platelet activation, signaling and aggregation 223/7348 262/10654 8.776829402799106e-10 8.928371780976932e-9 3.841732218718579e-9 5295/2788/2149/5777/8526/5579/2153/5770/5291/7042/64805/2770/5175/3959/5578/5582/5908/3082/388/5583/29106/11069/2769/7423/3709/5028/1432/3920/374354/2244/7114/3309/2534/3690/408/2162/2768/2782/87/2776/5894/10487/2885/11343/7040/9564/5874/54863/51266/350/1609/7043/2773/967/5879/5054/2787/5099/10411/1072/5290/3699/7018/6678/5340/7225/5336/813/7094/5594/10681/7414/10490/83706/7044/7534/6810/7123/2792/6714/6694/3671/7273/22927/1191/3273/146850/27154/226/5588/5880/2335/5294/1/2785/2783/2784/1445/5478/2771/94121/22915/7410/5580/2266/7409/7873/5154/3932/7076/2243/3710/801/5781/2151/2791/2147/805/928/5170/5590/351/6464/5747/51097/3937/7424/2316/3674/5552/409/6915/2157/7277/10451/334/1277/10447/150/10257/335/51706/308/6850/78991/8503/6403/197/4067/81/747/9948/998/3481/2786/54495/6654/5473/9162/8407/7450/387/29789/10916/5595/139322/151/160851/5321/54331/5005/59345/207/26090/7422/5004/51764/94235/3708/5196/3827/54518/1950/55970/2621/5216/2767/5768/346562/710/152/6647/23052/2793/23533/5265/391/5345/54676/2/1398/948/88/1675/5906/5341/3479/5155/5296/5581/51368/808/213/5660/9630/7057/1278/9002/2207/5627/6814/2790/10672 223 Human_SARS_coronavirus_2 R-HSA-1169408 ISG15 antiviral mechanism 70/7348 72/10654 1.2164982516775326e-9 1.2113581182197403e-8 5.212275681761408e-9 3839/23165/5335/348995/317649/57122/11274/23511/4734/23279/8672/23225/1973/3836/4599/9972/8021/7334/55746/7314/402569/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/1977/51191/6233/5610/6396/129401/4928/3838/5903/55706/7175/4600/3841/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/7318/1974/5595/3837/81929/9631/79023/23636/7316/53371/9688/5300/9775/5495/8480 70 Human_SARS_coronavirus_2 R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 70/7348 72/10654 1.2164982516775326e-9 1.2113581182197403e-8 5.212275681761408e-9 8773/55763/5563/71/7531/11127/51807/10971/347688/7533/2810/10381/7278/60412/5898/7846/81027/51552/23433/5879/79861/51422/4644/7534/6810/5872/4641/10376/11336/6844/9882/79058/801/4218/57148/805/84617/7532/57186/10382/7277/23216/5571/347733/208/5867/4012/10383/60/84790/5564/5565/22920/7280/7529/55770/23265/6517/10890/9371/10640/4627/207/112714/8766/149371/9847/808/54536/6814 70 Human_SARS_coronavirus_2 R-HSA-448424 Interleukin-17 signaling 70/7348 72/10654 1.2164982516775326e-9 1.2113581182197403e-8 5.212275681761408e-9 8454/3605/3725/9252/4790/1848/1432/3654/6196/5518/1386/55540/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/23118/64806/8517/5528/84818/9261/5519/5598/4208/6195/10454/27189/6233/2353/5600/5608/387522/79155/7867/64127/5602/3656/7189/112744/7311/23765/6416/5595/5516/1147/1845/6885/5604/10392/6500/7316/7335/4205/466/23291/132014/5609/1385/5599 70 Human_SARS_coronavirus_2 R-HSA-6799198 Complex I biogenesis 55/7348 55/10654 1.2553228709112748e-9 1.2412773003276522e-8 5.341013024561774e-9 4723/4719/4724/4715/4538/4695/4540/4696/4705/137682/4720/79133/51079/4702/55863/4536/4725/4541/4731/4707/55967/4716/126328/4700/4711/4712/55471/4710/51295/4714/4701/4726/4708/4713/4709/91942/51300/4722/4717/4535/29078/4704/51103/4729/4718/4728/374291/25915/4706/28976/54539/4698/4537/4694/80224 55 Human_SARS_coronavirus_2 R-HSA-422356 Regulation of insulin secretion 75/7348 78/10654 1.7857501255418736e-9 1.753507414941812e-8 7.545055354994173e-9 2788/6804/6833/5331/2740/2770/5578/11069/2769/3709/3767/9495/2782/3630/2776/8826/2181/6513/2787/10411/5567/3745/1131/784/10681/112/5573/111/2792/2785/2783/2784/2771/6844/2182/3710/2791/9254/5568/150/6616/5566/775/2864/23236/2641/2786/5577/3747/773/6812/54331/5575/59345/776/51764/94235/114/3708/4082/5330/3790/55970/2778/2767/10768/152/2793/5576/783/26251/948/5906/9630/2790 75 Human_SARS_coronavirus_2 R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 62/7348 63/10654 1.864029124187549e-9 1.8177497804146168e-8 7.821479737062818e-9 5689/11065/5682/7321/8697/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/5707/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 62 Human_SARS_coronavirus_2 R-HSA-380259 Loss of Nlp from mitotic centrosomes 68/7348 70/10654 2.4339370753096587e-9 2.3412156629169097e-8 1.0073867737407682e-8 7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 68 Human_SARS_coronavirus_2 R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 68/7348 70/10654 2.4339370753096587e-9 2.3412156629169097e-8 1.0073867737407682e-8 7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 68 Human_SARS_coronavirus_2 R-HSA-141424 Amplification of signal from the kinetochores 90/7348 96/10654 2.5685245878996008e-9 2.42126251152669e-8 1.0418296223199785e-8 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/79902/3796/5519/81565/91687/11243/83540/7514/54820/6396/64946/9793/140735/220134/4928/5903/55055/80776/1783/401541/79172/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/79023/55920/1781/4085/55166/79003/5527/701/57551 90 Human_SARS_coronavirus_2 R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 90/7348 96/10654 2.5685245878996008e-9 2.42126251152669e-8 1.0418296223199785e-8 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/79902/3796/5519/81565/91687/11243/83540/7514/54820/6396/64946/9793/140735/220134/4928/5903/55055/80776/1783/401541/79172/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/79023/55920/1781/4085/55166/79003/5527/701/57551 90 Human_SARS_coronavirus_2 R-HSA-8878159 Transcriptional regulation by RUNX3 90/7348 96/10654 2.5685245878996008e-9 2.42126251152669e-8 1.0418296223199785e-8 5689/6046/5682/182/5705/6696/5709/5695/9759/10413/4609/4089/22938/5711/1387/4088/5683/5699/5702/9794/6932/7040/3845/5696/5691/7314/5718/8463/51176/2648/5700/5707/55534/3280/84441/463/3683/865/83439/6714/9861/8850/5698/5692/5713/595/5710/7157/5719/6233/7004/1029/864/5706/10046/5714/6934/5688/5687/5708/5704/7311/5694/4851/3676/57154/5684/5720/2309/1499/10018/5690/5717/9491/10197/64750/7316/10213/1026/5715/5701/5685/5686/2033/861/5716/3516/5693/5721/4193 90 Human_SARS_coronavirus_2 R-HSA-1852241 Organelle biogenesis and maintenance 248/7348 296/10654 2.6135468665559746e-9 2.4473875955696347e-8 1.0530708183125504e-8 55763/5563/57728/1260/79867/55735/79718/7531/11190/203068/11127/54801/51807/1258/123016/85302/347688/1262/79441/10381/5116/7278/3313/5048/10576/5469/22832/10989/60412/8655/83658/6010/54585/51668/9702/132320/1432/1387/25813/7846/7840/6907/11064/84902/81027/4509/84100/2847/10499/23054/5518/1386/55835/57560/9572/85441/3054/23332/7019/166379/93323/96764/79659/79861/3797/84747/11020/10575/1454/9321/23408/150737/51422/10013/54806/5465/9727/91147/7978/54927/983/64784/79959/2747/5310/92104/4208/6604/80205/8729/10376/4508/10540/11336/117177/57545/55902/26005/54930/55764/54820/23322/6742/378/56623/5600/1453/6300/801/56912/9793/4218/140735/64216/805/6102/80173/582/84617/4899/90410/5442/11258/22981/8636/54903/80776/79135/3842/3418/7532/55125/10382/6753/79809/23410/8100/121441/7277/26146/585/8834/9814/4209/5147/23354/146057/9738/1639/255758/84303/55722/4957/50807/5566/5571/7283/347733/4580/22919/27077/22994/4867/5311/6648/1069/211/10651/5577/10383/583/5347/403/84790/22948/80184/22897/5564/23373/5565/22920/5108/261734/57787/7280/10806/9657/1778/55770/23265/139322/115106/10694/22995/55559/8841/9371/55081/28981/10142/6608/10640/27031/51134/95681/57539/200186/79989/112714/7203/1781/80321/8766/9611/23409/79598/54205/149371/10121/347240/84131/6950/55212/3320/79600/10733/6256/4751/9742/10498/80254/1385/200894/26123/808/54536/9662/55142/92482/129880/8648/8481/27241/51259/55755/64792/10891/26160 248 Human_SARS_coronavirus_2 R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 121/7348 134/10654 3.1859833043280704e-9 2.963802889684139e-8 1.2752758655828427e-8 5295/8454/5689/3725/4893/5335/4790/5682/5291/7321/143471/5705/5530/5709/5695/4792/3709/5711/5683/2534/5699/5702/2885/9846/3845/7334/3265/3551/5062/5696/5691/7314/5879/257397/5718/8945/5601/4773/5290/5700/122706/5707/5336/5594/4214/23198/23118/8517/5970/9861/5588/5698/5692/5713/5710/10454/5719/6233/7410/7409/3702/2353/3710/801/805/5170/6464/387522/4772/3937/4775/10451/5706/6850/8915/5714/5688/5687/4067/5708/5602/695/7189/6654/5704/7311/5694/5058/6416/997/5595/1147/9402/5684/5720/6885/5690/5532/5717/9491/6500/3708/10197/7316/10213/7335/10768/7322/5715/5701/23291/5685/5686/5609/5716/5296/808/5599/5693/5721/2207 121 Human_SARS_coronavirus_2 R-HSA-2219528 PI3K/AKT Signaling in Cancer 94/7348 101/10654 3.3923281208689668e-9 3.1351320019011234e-8 1.348995977889414e-8 5295/2308/374/2250/5291/7039/3082/941/2064/145957/2534/9965/2264/9542/2885/2475/8660/2252/2253/5879/1839/5290/3667/6801/8823/2065/3815/2069/84335/8074/7249/2260/2249/6714/2099/2248/2932/2247/5880/10000/7409/2246/2251/5154/3932/2931/5781/940/253260/5170/572/6199/2263/4233/64223/8503/5159/29851/3084/208/9365/10718/79109/5293/1956/2549/1147/8822/685/2309/842/207/1027/8817/2100/2254/152831/1950/1026/26281/10818/2261/2255/3164/391/5728/2066/27006/1385/5155/4254/5296/5156/4193 94 Human_SARS_coronavirus_2 R-HSA-3371556 Cellular response to heat stress 84/7348 89/10654 3.4234955134956087e-9 3.143391335118695e-8 1.3525498337665498e-8 23165/6782/573/7531/1915/817/9530/348995/472/57122/3313/23511/3305/23279/1387/259217/23225/3309/9531/2475/3306/27000/9972/23411/8021/6117/3312/55746/51182/818/3303/6118/5594/3308/84335/10049/10013/3337/10762/9261/79902/9883/2932/6396/129401/3297/57521/4928/5903/55706/7175/1410/4927/64223/6119/57805/3281/3310/7266/816/8086/3326/3304/10728/5595/815/81929/9631/116835/545/79023/23636/10808/53371/9532/9688/7415/3320/2033/6767/22824/9529/2288/8480 84 Human_SARS_coronavirus_2 R-HSA-5358351 Signaling by Hedgehog 133/7348 149/10654 3.465861872056224e-9 3.1617604432822585e-8 1.3604537603045825e-8 8454/5689/57728/5682/11127/1452/51684/143471/10381/5705/7278/8452/5709/9978/5695/107/3549/5711/7846/5683/408/5699/6400/5702/81027/83737/51009/6469/5696/5691/7314/5718/8945/79659/339745/5700/122706/5707/5567/10956/27152/23198/112/5573/2737/5727/8650/111/50846/9861/8405/2932/5698/5692/5713/10376/5710/2262/5719/6233/374654/27248/55764/23322/196883/115/84617/54903/10382/23288/79809/5568/409/79577/8100/7277/5706/113/84447/5714/5566/2736/5688/5687/347733/5708/55811/5577/5704/7311/147111/10383/84790/5694/7280/109/57154/5684/5720/55081/2735/5575/6608/5690/5717/9491/6500/57539/114/7289/10197/108/64750/132884/7316/10213/2778/50937/7415/5715/5701/5576/5685/5686/9742/5716/80199/23432/8481/5693/5721/5034/26160 133 Human_SARS_coronavirus_2 R-HSA-204998 Cell death signalling via NRAGE, NRIF and NADE 73/7348 76/10654 3.4973880423056965e-9 3.170068392192471e-8 1.3640285347184162e-8 9639/7984/7531/29/55160/8878/1894/23385/10276/84033/100271715/9138/836/23365/26230/57449/8997/26084/8874/121512/64857/7314/5879/9181/2245/84904/6453/9828/5664/6233/7410/7409/26574/128272/25791/55701/5663/445328/572/7204/27237/7074/10451/50650/221472/23229/22899/7189/6654/7311/54848/6655/389337/51107/5924/4804/10018/57580/835/9459/11214/23421/23370/9500/7316/4168/23263/50649/9826/4803/5599/89846/10672 73 Human_SARS_coronavirus_2 R-HSA-5678895 Defective CFTR causes cystic fibrosis 60/7348 61/10654 3.8173937665340485e-9 3.438085850878436e-8 1.4793520597094738e-8 5689/5682/143471/91319/5705/5709/5695/5711/5683/5699/6400/5702/51009/5696/5691/7314/5718/5700/122706/5707/10956/79139/91445/23198/9861/5698/5692/5713/5710/5719/10613/6233/27248/6048/5706/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 60 Human_SARS_coronavirus_2 R-HSA-69615 G1/S DNA Damage Checkpoints 66/7348 68/10654 4.861382566304611e-9 4.3491767570032856e-8 1.871379561935457e-8 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/993/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/1111/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 66 Human_SARS_coronavirus_2 R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 72/7348 75/10654 4.890517003985307e-9 4.3491767570032856e-8 1.871379561935457e-8 23165/8683/6431/84271/199746/348995/57122/23511/65109/23279/728343/23225/9877/9972/8021/55746/7919/6432/8563/6430/56001/80145/10762/22794/9785/11338/29107/4116/79902/9883/51213/10250/26097/51362/57187/6396/129401/79228/2733/84324/4928/5903/55706/7175/6428/10212/55110/84321/6429/4927/10569/9295/10482/8086/9939/6426/22916/10921/81929/9631/79023/23636/4686/53371/7307/9688/9984/10189/9775/84248/6427/8480 72 Human_SARS_coronavirus_2 R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 59/7348 60/10654 5.460531178220749e-9 4.708043345124475e-8 2.025793980110137e-8 8454/5689/9134/5682/5705/5709/5753/5695/5711/5683/5699/5702/8900/5696/5691/7314/5718/5700/5707/898/890/9861/6502/5698/5692/5713/595/5710/5719/6233/1163/1019/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/5690/5717/1027/9491/6500/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721 59 Human_SARS_coronavirus_2 R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 59/7348 60/10654 5.460531178220749e-9 4.708043345124475e-8 2.025793980110137e-8 8454/5689/5682/9039/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/5970/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 59 Human_SARS_coronavirus_2 R-HSA-5610780 Degradation of GLI1 by the proteasome 59/7348 60/10654 5.460531178220749e-9 4.708043345124475e-8 2.025793980110137e-8 8454/5689/5682/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/83737/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/8650/9861/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/2735/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Human_SARS_coronavirus_2 R-HSA-5610783 Degradation of GLI2 by the proteasome 59/7348 60/10654 5.460531178220749e-9 4.708043345124475e-8 2.025793980110137e-8 8454/5689/5682/1452/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/9861/2932/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/2736/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Human_SARS_coronavirus_2 R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 59/7348 60/10654 5.460531178220749e-9 4.708043345124475e-8 2.025793980110137e-8 8454/5689/5682/1452/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/2737/9861/2932/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Human_SARS_coronavirus_2 R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 51/7348 51/10654 5.597633701607839e-9 4.797002457014233e-8 2.064071629683784e-8 6227/6206/1965/6234/27335/6191/8668/6224/8662/6202/6218/6192/3921/8665/6208/6203/8666/6222/8667/6231/8663/8894/6207/6233/140032/51386/6188/1968/6230/8669/6194/6232/6193/6210/6229/6205/6235/6223/8664/6187/6217/51065/10480/8661/6209/1964/6204/6228/3646/6189/6201 51 Human_SARS_coronavirus_2 R-HSA-4420097 VEGFA-VEGFR2 Pathway 92/7348 99/10654 6.237938843651671e-9 5.313521400556303e-8 2.286321275606003e-8 5295/4893/857/5335/71/5579/5291/5578/3709/1432/2534/9475/3690/5603/2475/6093/8440/9564/3845/3265/8877/5062/5829/5879/26999/5290/5567/10006/57761/5921/1500/9261/6714/10810/10000/3728/7410/5580/7409/23191/3685/3791/3710/117145/1535/5600/6300/801/10787/253260/805/5170/4688/5590/653361/6461/5747/5568/3315/10451/1793/10152/7867/64223/5566/1003/5063/998/208/79109/2185/387/60/5058/63916/25759/1495/1499/4690/207/7422/10458/3708/10768/8936/3320/4846/1398/9844/5296/808/1536 92 Human_SARS_coronavirus_2 R-HSA-6807505 RNA polymerase II transcribes snRNA genes 71/7348 74/10654 6.834779039739565e-9 5.787052432450147e-8 2.4900739268638314e-8 6884/51585/5431/5435/23379/5433/2960/55656/5439/10302/904/65123/55197/2959/79871/5438/6667/29101/79664/25896/23248/1025/7702/6829/2957/2963/5434/26173/5436/26512/6878/55756/58490/2962/51808/8812/129685/905/5452/64859/22936/6621/6880/6908/80237/6619/6882/2961/5432/22916/6618/6877/5440/57508/5430/5451/55174/6617/5441/84524/4686/2958/5437/92105/6827/80789/57117/51593/79035/1022/8178 71 Human_SARS_coronavirus_2 R-HSA-5676590 NIK-->noncanonical NF-kB signaling 58/7348 59/10654 7.808579798762907e-9 6.494901079676913e-8 2.7946496121888306e-8 8454/5689/5682/9039/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 58 Human_SARS_coronavirus_2 R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 58/7348 59/10654 7.808579798762907e-9 6.494901079676913e-8 2.7946496121888306e-8 5689/5682/143471/5705/5709/5695/84515/4998/5711/5683/990/5699/5702/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/4999/5000/5706/5714/51053/5688/5687/5708/81620/5704/23595/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 58 Human_SARS_coronavirus_2 R-HSA-983189 Kinesins 58/7348 59/10654 7.808579798762907e-9 6.494901079676913e-8 2.7946496121888306e-8 64837/11127/51807/347688/3798/10381/7278/285643/10112/64147/7846/81027/11004/10749/81930/113220/79861/3797/29127/55605/3796/124602/55614/89953/56992/10376/3835/147700/3833/9493/3831/84617/9585/10382/3832/7277/23303/26153/1062/146909/347733/90990/23046/10383/24137/84790/84643/22920/7280/55582/9371/23095/112714/547/3834/55083/3799/221458 58 Human_SARS_coronavirus_2 R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 76/7348 80/10654 8.212258046406512e-9 6.79072098106363e-8 2.92193607314433e-8 3839/23165/201626/5335/348995/317649/57122/11274/23511/4734/23279/8672/23225/1973/3836/4599/9972/8021/7334/55746/7314/402569/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/1977/51191/6233/5610/4940/6396/129401/4928/3838/5903/55706/7175/2316/4600/3841/8638/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/7318/1974/5595/3837/81929/9631/79023/23636/7316/53371/9688/6041/6059/5300/9775/5495/8480 76 Human_SARS_coronavirus_2 R-HSA-5633007 Regulation of TP53 Activity 141/7348 160/10654 9.177431778491273e-9 7.544702636503871e-8 3.2463620367000956e-8 6884/6875/5563/83990/64769/9156/1763/1459/7486/6874/9212/5982/1460/11200/472/79813/639/28996/84289/1457/6790/29117/4194/5928/1432/4683/56950/1107/8900/6873/5371/8396/2475/672/6881/51616/5518/6117/11198/7159/51230/83695/7314/5515/23368/23774/6118/3622/51422/79837/117584/890/983/5519/27154/83860/57459/10000/5985/900/7994/3066/7157/5984/6233/10419/5600/6883/7874/5608/5884/5810/26155/26013/253260/5170/7862/1029/9219/8445/204851/6878/5931/580/80196/54971/641/1108/8148/64223/6119/3364/5571/10524/54457/1616/6794/54815/1111/8626/208/79109/7311/7161/5562/6880/6908/5983/5564/6882/5565/1020/53615/6877/5516/1017/5305/5883/25946/10111/207/22974/6749/545/8550/7316/6872/6879/10848/9099/2033/3065/91875/5527/5932/8851/5300/7156/138474/10919/4193 141 Human_SARS_coronavirus_2 R-HSA-5654738 Signaling by FGFR2 70/7348 73/10654 9.546562712150728e-9 7.802797499989092e-8 3.357416031410478e-8 5295/4893/2250/5335/54845/5431/5435/5433/8569/5439/7072/2885/7073/5518/2252/2253/3845/3265/7314/5515/5290/8823/5594/8074/5438/3185/2249/6714/2248/4670/2247/6233/2246/2251/5781/5725/2963/5434/6464/5436/673/2263/2962/80004/6654/7311/2549/5432/22916/5595/5516/8822/10253/5440/23543/5430/3178/8817/10817/5441/2254/4686/7316/26281/10818/867/5437/2255/27006/3187 70 Human_SARS_coronavirus_2 R-HSA-69563 p53-Dependent G1 DNA Damage Response 64/7348 66/10654 9.692233652690285e-9 7.831324791373751e-8 3.369690857897736e-8 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Human_SARS_coronavirus_2 R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 64/7348 66/10654 9.692233652690285e-9 7.831324791373751e-8 3.369690857897736e-8 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Human_SARS_coronavirus_2 R-HSA-72187 mRNA 3'-end processing 57/7348 58/10654 1.116284139783059e-8 8.968328259393438e-8 3.858924837288326e-8 8683/6431/84271/51585/199746/81608/1477/65109/9877/7919/53981/6432/8563/6430/11051/80145/8106/22794/9785/11338/4116/1478/51213/10250/26097/51362/23283/10914/57187/79228/84324/6428/10212/55110/84321/6429/10898/10569/9295/51692/9939/6426/22916/1479/10921/79869/29894/4686/8189/10978/7307/9984/10189/9775/84248/6427/55339 57 Human_SARS_coronavirus_2 R-HSA-6806834 Signaling by MET 75/7348 79/10654 1.1361816450780552e-8 9.076614949945593e-8 3.905518827565364e-8 5295/3675/4893/5770/10653/5908/3082/1280/1289/3688/3910/1290/3908/6456/30011/2885/3845/3265/1399/7314/5879/255631/3918/5290/8027/3911/2060/284217/9101/6714/9146/6455/2335/64759/3909/84951/6233/57610/5781/1302/6464/85440/5747/382/1277/3912/6774/4233/5795/2889/5771/3913/6654/5867/7311/2549/53916/85301/10048/7316/3915/1301/1281/3673/867/3914/200958/1398/5906/23163/50509/1278/10319/10254/6457 75 Human_SARS_coronavirus_2 R-HSA-199992 trans-Golgi Network Vesicle Budding 69/7348 72/10654 1.3326505412101919e-8 1.0586336321748378e-7 4.55512721951207e-8 27131/8773/8906/162/1176/27243/5286/1212/1174/1785/8546/11154/7037/3482/408/6456/7164/3312/1362/26258/25977/10618/6643/10053/6810/55330/8301/9146/8729/4074/2495/388552/152503/6844/54885/1213/2580/1211/23431/8907/351/84062/9685/9179/9026/8775/9829/8905/51429/64746/8673/23557/2512/164/130340/6272/1522/2799/2804/2647/7163/286451/9698/5878/81567/10717/6845/375/4952 69 Human_SARS_coronavirus_2 R-HSA-4641258 Degradation of DVL 56/7348 57/10654 1.5952880757242087e-8 1.2601884575832576e-7 5.422384638451001e-8 5689/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/1855/5696/5691/7314/5718/5700/122706/5707/1856/23198/59349/9861/5698/5692/5713/5710/5719/6233/1857/5706/5714/5688/5687/5708/51339/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/23072/5693/5721 56 Human_SARS_coronavirus_2 R-HSA-8876198 RAB GEFs exchange GTP for GDP on RABs 84/7348 90/10654 1.6517244812023027e-8 1.2975213424555866e-7 5.5830219306136327e-8 5869/116442/126003/7531/22878/1122/54453/10981/5861/5866/23011/9610/60684/3257/414918/51762/51552/126432/201475/5874/79961/221960/2665/79090/58485/5868/81846/51622/51209/5872/9827/80006/5870/8408/9909/10000/51112/117177/83696/1121/23682/27095/6399/7109/4218/7879/2664/201627/27342/23258/5864/10260/57679/81876/259173/6305/51693/8567/208/79890/22879/54734/57589/84315/22931/51399/10890/207/122553/79958/57706/22930/55667/26130/25782/9367/51560/11021/5873/5878/11031/338382/89781/160518 84 Human_SARS_coronavirus_2 R-HSA-450294 MAP kinase activation 62/7348 64/10654 1.928675277618244e-8 1.5067109627360204e-7 6.483130622060745e-8 8454/3725/9252/4790/1848/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/23118/8517/5528/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/387522/79155/7867/64127/5602/3656/7189/7311/6416/5595/5516/1147/1845/6885/5604/10392/6500/7316/7335/4205/466/23291/5609/1385/5599 62 Human_SARS_coronavirus_2 R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 55/7348 56/10654 2.279087883069962e-8 1.749644479034707e-7 7.528433774153659e-8 5689/5682/26986/143471/5705/5709/5695/5711/5683/5699/5702/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/9861/5698/5692/5713/1981/5710/5719/6233/3315/5706/5714/5688/5687/5708/5704/7311/5694/3304/5684/5720/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 55 Human_SARS_coronavirus_2 R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 55/7348 56/10654 2.279087883069962e-8 1.749644479034707e-7 7.528433774153659e-8 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/51009/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/9861/5698/5692/5713/5710/5719/6233/27248/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 55 Human_SARS_coronavirus_2 R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 78/7348 83/10654 2.2891388162759605e-8 1.749644479034707e-7 7.528433774153659e-8 8454/5689/4893/4790/5579/5682/143471/5705/5530/5709/5695/4792/5711/5683/5699/5702/4794/3845/3265/3551/5696/5691/7314/5718/8945/4773/5966/5700/122706/5707/23198/8517/5970/25780/9861/5698/5692/5713/5710/2280/5478/5719/6233/801/805/4772/4775/5706/8915/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/5690/5532/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5716/808/5693/5721 78 Human_SARS_coronavirus_2 R-HSA-1236974 ER-Phagosome pathway 78/7348 83/10654 2.2891388162759605e-8 1.749644479034707e-7 7.528433774153659e-8 8773/5689/5682/3107/55176/811/143471/5705/10333/5709/5695/567/3106/5711/5683/929/5699/5702/3551/5696/5691/7314/5718/10952/5700/122706/5707/23198/6892/8517/6810/7096/9861/5698/5692/5713/5710/5719/6233/6890/5706/9554/29927/5714/5688/5687/5708/2923/695/5704/7311/5694/8673/3105/23643/1147/5684/5720/5690/5717/9491/10197/7099/4615/23480/6891/7316/10213/5715/5701/9341/5685/5686/948/5716/7097/5693/5721 78 Human_SARS_coronavirus_2 R-HSA-167161 HIV Transcription Initiation 47/7348 47/10654 2.4943456097276202e-8 1.8087203549512078e-7 7.782627597422751e-8 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_SARS_coronavirus_2 R-HSA-167162 RNA Polymerase II HIV Promoter Escape 47/7348 47/10654 2.4943456097276202e-8 1.8087203549512078e-7 7.782627597422751e-8 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_SARS_coronavirus_2 R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 47/7348 47/10654 2.4943456097276202e-8 1.8087203549512078e-7 7.782627597422751e-8 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Human_SARS_coronavirus_2 R-HSA-6802949 Signaling by RAS mutants 47/7348 47/10654 2.4943456097276202e-8 1.8087203549512078e-7 7.782627597422751e-8 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Human_SARS_coronavirus_2 R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 47/7348 47/10654 2.4943456097276202e-8 1.8087203549512078e-7 7.782627597422751e-8 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Human_SARS_coronavirus_2 R-HSA-73776 RNA Polymerase II Promoter Escape 47/7348 47/10654 2.4943456097276202e-8 1.8087203549512078e-7 7.782627597422751e-8 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_SARS_coronavirus_2 R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 47/7348 47/10654 2.4943456097276202e-8 1.8087203549512078e-7 7.782627597422751e-8 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_SARS_coronavirus_2 R-HSA-75953 RNA Polymerase II Transcription Initiation 47/7348 47/10654 2.4943456097276202e-8 1.8087203549512078e-7 7.782627597422751e-8 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_SARS_coronavirus_2 R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 47/7348 47/10654 2.4943456097276202e-8 1.8087203549512078e-7 7.782627597422751e-8 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Human_SARS_coronavirus_2 R-HSA-9649948 Signaling downstream of RAS mutants 47/7348 47/10654 2.4943456097276202e-8 1.8087203549512078e-7 7.782627597422751e-8 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Human_SARS_coronavirus_2 R-HSA-1226099 Signaling by FGFR in disease 61/7348 63/10654 2.71863930871732e-8 1.9513482144803505e-7 8.396331928605989e-8 5295/4893/11052/2250/5335/9530/613/5431/6776/5435/5433/11064/5439/2264/2885/9846/2252/2253/3845/3265/7750/8805/26127/5290/8823/8074/2260/5438/2249/2248/399687/2247/2246/2251/1523/2963/5434/5436/9208/6774/2263/6772/2962/6654/11160/2549/5432/22916/8822/5440/5430/8817/5441/2254/4686/26281/10818/2261/5437/2255/27006 61 Human_SARS_coronavirus_2 R-HSA-9033241 Peroxisomal protein import 61/7348 63/10654 2.71863930871732e-8 1.9513482144803505e-7 8.396331928605989e-8 26063/7321/10965/10901/1384/23600/10005/8239/3417/390916/23417/4358/5192/7314/1891/54677/26061/8528/847/7323/2053/8309/10455/5189/196743/8540/11001/6233/1610/83752/373156/5264/189/3155/5193/30/122970/51/55825/1962/54363/5830/51179/7311/6342/5195/3295/51268/8310/7316/7322/3416/4843/5190/5828/283927/219743/570/5194/5191/8443 61 Human_SARS_coronavirus_2 R-HSA-9013694 Signaling by NOTCH4 77/7348 82/10654 3.1339944258901976e-8 2.238115211216535e-7 9.630243371422299e-8 8454/5689/5682/182/23385/5705/5709/9978/5695/22938/5711/1387/4088/5683/5699/4853/5702/9794/5696/5691/7314/5718/2648/5700/5707/55534/3280/84441/7534/102/5664/9861/8850/5698/5692/5713/5710/5719/6233/2324/5663/5706/10460/10046/5714/5688/5687/5708/59/4855/5704/7311/51107/5694/4851/5684/5720/23462/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/2033/55294/5716/54567/3516/5693/5721 77 Human_SARS_coronavirus_2 R-HSA-199418 Negative regulation of the PI3K/AKT network 100/7348 110/10654 3.186538820905765e-8 2.264203966211433e-7 9.742499013401388e-8 5295/374/3643/2250/23035/5291/5526/7039/3082/941/2064/145957/2534/9965/2264/3630/3654/9542/2885/8396/8660/5518/2252/2253/5879/5515/23396/1839/5290/3667/6801/8823/2065/3815/5594/2069/8074/79837/57761/8395/2260/5528/2249/6714/2099/2248/5519/2247/5880/10000/7409/2246/2251/5154/3932/117145/8394/5781/940/23239/2263/4233/8503/5159/29851/3084/5529/7189/208/9365/10718/5293/1956/2549/5595/5516/8822/685/5305/5525/207/8817/4615/2100/2254/152831/1950/26281/10818/2261/2255/391/5728/2066/27006/5527/5155/4254/5296/5156 100 Human_SARS_coronavirus_2 R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 54/7348 55/10654 3.254890082783426e-8 2.2784230579483984e-7 9.803681437461283e-8 8454/5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/26271/5706/5714/5688/5687/5708/5704/51343/7311/5694/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 54 Human_SARS_coronavirus_2 R-HSA-4641257 Degradation of AXIN 54/7348 55/10654 3.254890082783426e-8 2.2784230579483984e-7 9.803681437461283e-8 5689/5682/143471/5705/5709/5695/5711/5683/5699/8312/5702/80351/5696/5691/7314/5718/5700/122706/5707/23198/9861/81847/5698/5692/5713/5710/8313/5719/6233/5706/8658/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/5716/5693/5721 54 Human_SARS_coronavirus_2 R-HSA-8941858 Regulation of RUNX3 expression and activity 54/7348 55/10654 3.254890082783426e-8 2.2784230579483984e-7 9.803681437461283e-8 5689/5682/5705/5709/5695/5711/5683/5699/5702/7040/5696/5691/7314/5718/5700/5707/865/6714/9861/5698/5692/5713/5710/5719/6233/1029/864/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/2033/5716/5693/5721/4193 54 Human_SARS_coronavirus_2 R-HSA-8948751 Regulation of PTEN stability and activity 66/7348 69/10654 3.611926622581406e-8 2.5158937164187727e-7 1.0825478806596076e-7 5689/5682/1459/1460/143471/5705/5709/5695/1457/4734/11060/5711/5683/5699/2444/5702/8975/80351/5696/5691/7314/5718/5700/122706/5707/23198/9861/81847/5698/10000/5692/5713/5710/5719/6233/331/23608/5706/8658/5714/5688/5687/5708/208/5704/7311/5694/5684/5720/10273/207/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5728/5987/5716/5693/5721 66 Human_SARS_coronavirus_2 R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 112/7348 125/10654 3.6988407077103134e-8 2.5638042944619524e-7 1.1031630180890409e-7 56955/4240/3270/9210/10272/2153/1511/7857/29106/91851/6696/51156/1435/265/11098/10130/2200/80341/375056/1114/720/10117/3956/3569/54972/2519/8720/7018/5340/10618/11167/813/5179/8074/51246/348/4924/4313/3484/102/8614/336/6694/4148/174/57104/2335/7466/116519/2266/51280/7076/2243/84141/3488/2147/8542/4221/351/4052/7184/56975/334/3912/338/64856/335/5611/197/3053/3895/5624/1000/54757/3481/8404/255738/3913/652/3817/57719/147111/2719/3487/3371/54587/401138/3486/7425/6383/3827/3490/5589/2621/3915/5768/1471/1462/10232/462/3698/5265/1758/258/11320/5954/3479/213/10970/5034/1356/718 112 Human_SARS_coronavirus_2 R-HSA-4086398 Ca2+ pathway 60/7348 62/10654 3.8301795929323335e-8 2.6418897289786923e-7 1.1367619022926259e-7 2788/2780/5158/5331/5578/27327/2775/5530/3709/2782/192669/6932/4343/3845/2787/51176/2535/51701/8322/10681/83439/8323/2792/7481/2785/2783/2784/7474/3710/7855/26523/801/2791/7976/805/5145/4772/6934/5148/23236/2786/27161/815/54331/6885/1499/59345/5532/57690/51764/94235/3708/5330/192670/55970/2793/23112/808/2790/5592 60 Human_SARS_coronavirus_2 R-HSA-1234174 Cellular response to hypoxia 71/7348 75/10654 4.134543017437768e-8 2.837982440124759e-7 1.221137385834967e-7 5689/5682/64344/7321/3091/143471/5705/5709/9978/5695/5711/1387/5683/5699/126374/25994/7428/5702/2056/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/405/768/112399/84962/5706/5714/5688/5687/5708/5704/7311/2034/55662/5694/5684/5720/7422/5690/5717/9491/10197/7316/10213/8994/7322/5715/5701/112398/5685/5686/2033/8453/5716/54583/5693/5721 71 Human_SARS_coronavirus_2 R-HSA-74751 Insulin receptor signalling cascade 53/7348 54/10654 4.646868363790908e-8 3.1438621370336576e-7 1.3527524121234677e-7 5295/3643/4893/2250/5291/9965/2264/3630/2885/8660/9846/2252/2253/3845/3265/54106/5290/3667/8823/5594/8074/57761/2260/2249/2248/2247/2246/2251/117145/5781/30849/5170/6464/2322/5140/2263/208/9365/6654/2549/5595/8822/8817/2254/152831/5289/26281/10818/2261/2255/27006/5296/2887 53 Human_SARS_coronavirus_2 R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 53/7348 54/10654 4.646868363790908e-8 3.1438621370336576e-7 1.3527524121234677e-7 8454/5689/5682/143471/5705/5709/9978/5695/6790/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/23194/5693/5721 53 Human_SARS_coronavirus_2 R-HSA-9604323 Negative regulation of NOTCH4 signaling 53/7348 54/10654 4.646868363790908e-8 3.1438621370336576e-7 1.3527524121234677e-7 8454/5689/5682/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/5707/7534/9861/5698/5692/5713/5710/5719/6233/5706/10460/5714/5688/5687/5708/4855/5704/7311/5694/5684/5720/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721 53 Human_SARS_coronavirus_2 R-HSA-8943724 Regulation of PTEN gene transcription 59/7348 61/10654 5.393308482297868e-8 3.6314943780805645e-7 1.562572582841187e-7 1912/3725/6591/1822/9112/6045/80012/1911/5928/10325/23512/57332/1107/2475/1386/10670/64121/23186/2146/51564/5594/84232/100532731/7101/84733/57459/3066/7157/8726/57521/6015/28956/9219/8535/5931/58528/1108/2122/64223/10014/54815/6009/55004/57504/648/23466/53615/5595/8841/5468/5978/153129/57167/1958/8649/6615/3065/23028/10542 59 Human_SARS_coronavirus_2 R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 89/7348 97/10654 6.029866424313648e-8 4.0408678312699045e-7 1.7387192782505806e-7 8454/3725/9252/4790/1848/4792/177/1432/929/3654/6196/5518/1386/6197/64145/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/30849/5608/4791/3665/351/387522/8411/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/7335/4205/5289/4793/3146/466/23291/6288/6285/5609/1385/5599/353376/148022 89 Human_SARS_coronavirus_2 R-HSA-169911 Regulation of Apoptosis 52/7348 53/10654 6.6317545476714e-8 4.402488699721765e-7 1.8943188181636124e-7 5689/5682/4976/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/115209/5715/79658/5701/5685/5686/5716/5693/5721 52 Human_SARS_coronavirus_2 R-HSA-2428924 IGF1R signaling cascade 52/7348 53/10654 6.6317545476714e-8 4.402488699721765e-7 1.8943188181636124e-7 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/8471/2246/2251/117145/5781/30849/5170/6464/2322/5140/2263/3481/208/9365/6654/2549/3480/8822/8817/2254/152831/5289/26281/10818/2261/2255/27006/3479/5296 52 Human_SARS_coronavirus_2 R-HSA-111885 Opioid Signalling 84/7348 91/10654 6.910613892224387e-8 4.560571008830605e-7 1.962339047944681e-7 2788/2780/5331/2770/817/5578/5582/2775/5530/107/3709/4988/2774/2782/5499/5518/5143/2773/5515/2787/818/84152/5567/5594/10681/5142/112/5573/5528/111/5443/2792/5519/2785/2783/2784/5613/2771/5332/5580/3710/196883/115/801/2791/805/3838/2781/5568/113/10645/5566/23236/816/2786/5577/1020/5141/109/5516/5533/815/5321/54331/5575/59345/5532/51764/94235/114/3708/5330/108/2779/5173/55970/10768/346562/2793/5576/1385/5144/808/2790 84 Human_SARS_coronavirus_2 R-HSA-1169091 Activation of NF-kappaB in B cells 64/7348 67/10654 6.998896102660829e-8 4.560571008830605e-7 1.962339047944681e-7 8454/5689/4790/5579/5682/143471/5705/5709/5695/4792/5711/5683/5699/5702/4794/3551/5696/5691/7314/5718/8945/5966/5700/122706/5707/23198/8517/5970/9861/5698/5692/5713/5710/5719/6233/5706/8915/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/5690/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5716/5693/5721 64 Human_SARS_coronavirus_2 R-HSA-1650814 Collagen biosynthesis and modifying enzymes 64/7348 67/10654 6.998896102660829e-8 4.560571008830605e-7 1.962339047944681e-7 871/169044/256076/1280/1289/1300/7093/1290/1303/8985/1285/9509/1296/5118/255631/1294/7373/1284/1305/1307/1298/84570/5033/1295/1288/1292/1293/57642/1302/1291/1310/1286/1287/1308/5352/91522/1277/23127/5351/7092/81578/340267/5479/1282/85301/64175/10491/283208/1299/8974/136227/140766/9508/79709/649/1301/1281/1297/1306/50509/131873/80781/1278/5034 64 Human_SARS_coronavirus_2 R-HSA-73856 RNA Polymerase II Transcription Termination 64/7348 67/10654 6.998896102660829e-8 4.560571008830605e-7 1.962339047944681e-7 8683/6431/84271/51585/199746/81608/1477/65109/9877/7919/53981/6432/8563/6430/11051/80145/8106/22794/9785/11338/4116/1478/51213/10250/26097/51362/23283/6636/10914/57187/79228/84324/6635/7884/6428/10212/84967/6637/55110/84321/6429/10898/10569/9295/51692/9939/6426/22916/1479/10921/79869/29894/4686/8189/10978/7307/9984/10189/6634/9775/84248/6427/55339/6628 64 Human_SARS_coronavirus_2 R-HSA-194138 Signaling by VEGF 97/7348 107/10654 7.407675574035076e-8 4.804795074167706e-7 2.0674246652787417e-7 5295/4893/857/5335/71/5579/5291/5578/8829/7423/3709/1432/2534/9475/3690/5603/2475/6093/8440/9564/3845/3265/8877/5062/5829/5879/26999/5290/5567/10006/57761/5921/1500/9261/6714/10810/10000/3728/7410/5580/2324/7409/23191/3685/3791/3710/117145/1535/5600/6300/801/10787/253260/805/5170/4688/5590/653361/6461/5747/7424/5568/3315/10451/1793/10152/7867/64223/5566/1003/5063/998/208/79109/2185/387/60/5058/63916/25759/1495/1499/4690/207/7422/10458/3708/10768/8936/3320/4846/1398/9844/5228/5296/808/1536 97 Human_SARS_coronavirus_2 R-HSA-8948216 Collagen chain trimerization 44/7348 44/10654 7.646735681822288e-8 4.937207421961971e-7 2.1243995309268365e-7 169044/256076/1280/1289/1300/1290/1303/1285/1296/255631/1294/7373/1284/1305/1307/1298/84570/1295/1288/1292/1293/57642/1302/1291/1310/1286/1287/1308/91522/1277/81578/340267/1282/85301/1299/136227/1301/1281/1297/1306/50509/131873/80781/1278 44 Human_SARS_coronavirus_2 R-HSA-983705 Signaling by the B Cell Receptor (BCR) 101/7348 112/10654 7.849588991022929e-8 5.045144924230192e-7 2.1708432712015568e-7 5295/8454/5689/5777/4893/4790/5579/5682/84876/143471/5705/5530/5709/5695/4792/3709/5711/5683/2534/5699/5702/30011/2885/4794/3845/3265/3551/933/5696/5691/7314/6786/5718/8945/4773/5966/5700/122706/5707/5336/23198/8517/5970/25780/9861/5698/5692/5713/5710/2280/5478/5719/6233/7409/3710/801/805/4772/4775/5706/7220/6850/8915/5714/5688/5687/4067/5708/695/6654/5704/7311/5293/5694/1147/5684/5720/6885/4690/640/5690/5532/5717/9491/6500/3708/10197/7316/10213/10768/4793/5715/5701/23291/5685/5686/974/5716/808/5693/5721 101 Human_SARS_coronavirus_2 R-HSA-1474290 Collagen formation 83/7348 90/10654 9.29864915264584e-8 5.86745939984069e-7 2.5246717286592114e-7 871/169044/256076/84171/1280/1289/84695/1300/7093/4015/1290/1303/8985/1285/9509/1296/5118/3655/255631/1294/3918/7373/1284/1305/1307/1515/1298/5339/84570/5033/3909/1295/1288/1292/1293/57642/7837/3691/1302/1291/1508/1514/1310/1286/1287/1308/5352/91522/4318/1277/23127/5351/7092/81578/340267/5479/1282/85301/64175/10491/283208/1299/8974/136227/140766/9508/79709/4016/649/667/1301/1281/1297/4017/3914/1306/1520/50509/131873/80781/1278/977/5034 83 Human_SARS_coronavirus_2 R-HSA-180534 Vpu mediated degradation of CD4 51/7348 52/10654 9.460967066221197e-8 5.86745939984069e-7 2.5246717286592114e-7 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/920/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_SARS_coronavirus_2 R-HSA-2428928 IRS-related events triggered by IGF1R 51/7348 52/10654 9.460967066221197e-8 5.86745939984069e-7 2.5246717286592114e-7 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/8471/2246/2251/117145/5781/30849/5170/2322/5140/2263/3481/208/9365/6654/2549/3480/8822/8817/2254/152831/5289/26281/10818/2261/2255/27006/3479/5296 51 Human_SARS_coronavirus_2 R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 51/7348 52/10654 9.460967066221197e-8 5.86745939984069e-7 2.5246717286592114e-7 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_SARS_coronavirus_2 R-HSA-69610 p53-Independent DNA Damage Response 51/7348 52/10654 9.460967066221197e-8 5.86745939984069e-7 2.5246717286592114e-7 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_SARS_coronavirus_2 R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 51/7348 52/10654 9.460967066221197e-8 5.86745939984069e-7 2.5246717286592114e-7 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_SARS_coronavirus_2 R-HSA-72165 mRNA Splicing - Minor Pathway 51/7348 52/10654 9.460967066221197e-8 5.86745939984069e-7 2.5246717286592114e-7 6633/6431/4904/51639/23450/5431/5435/5433/9416/8233/23020/5439/9410/10907/10262/6432/83443/10081/5438/9343/6636/2963/6635/5434/6632/24148/154007/5436/6637/55954/57819/2962/6426/5432/22916/23451/5440/55599/5430/85437/11325/5441/79622/10594/4686/5437/11066/6634/6427/10992/6628 51 Human_SARS_coronavirus_2 R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 51/7348 52/10654 9.460967066221197e-8 5.86745939984069e-7 2.5246717286592114e-7 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/2932/5698/5692/5713/595/5710/5719/6233/1019/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_SARS_coronavirus_2 R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 63/7348 66/10654 9.73273399581177e-8 6.00964448475015e-7 2.585851643106966e-7 5689/5682/64344/7321/3091/143471/5705/5709/9978/5695/5711/5683/5699/126374/7428/5702/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/112399/84962/5706/5714/5688/5687/5708/5704/7311/2034/5694/5684/5720/5690/5717/9491/10197/7316/10213/8994/7322/5715/5701/112398/5685/5686/8453/5716/54583/5693/5721 63 Human_SARS_coronavirus_2 R-HSA-168898 Toll-like Receptor Cascades 135/7348 155/10654 1.0203402109581537e-7 6.272874166499257e-7 2.6991150660586406e-7 8454/3725/9252/4790/7321/1848/1785/6280/10333/4792/59307/177/1432/2244/929/3654/6196/1759/5518/7187/1386/6197/64145/7334/3551/51231/7314/5515/257397/54106/23098/11035/8945/1326/5601/5606/8737/8767/5336/1849/29110/5594/6271/4214/23118/841/8517/5528/7323/1515/5970/7096/9261/5519/5598/4208/6195/10454/3661/6233/51311/10010/2266/2353/2243/8772/5600/5781/30849/5608/4791/671/1508/1514/3665/351/81793/387522/7184/3684/8411/330/51295/7098/338/79155/6279/8651/26052/7867/64127/5602/3656/57162/695/7189/81622/7311/9641/6416/51284/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/7335/4205/5289/4793/5775/3146/7322/329/466/23291/6288/6285/5609/948/1520/1385/5599/353376/7097/3689/148022 135 Human_SARS_coronavirus_2 R-HSA-3000171 Non-integrin membrane-ECM interactions 57/7348 59/10654 1.0675929697126032e-7 6.506795082644918e-7 2.799767406959549e-7 6385/5578/1280/1289/7448/1300/3688/3693/3910/1290/3908/1605/3690/87/6382/7040/1285/3655/3918/375790/3911/1284/284217/1756/2247/2335/3909/1288/3685/5154/9672/3691/1302/1286/1287/8573/7276/1277/3912/59277/3913/51399/3371/1282/3339/6383/3915/1301/1281/3673/3914/780/5155/50509/7057/1278/10319 57 Human_SARS_coronavirus_2 R-HSA-5387390 Hh mutants abrogate ligand secretion 57/7348 59/10654 1.0675929697126032e-7 6.506795082644918e-7 2.799767406959549e-7 5689/5682/143471/5705/5709/5695/3549/5711/5683/5699/6400/5702/51009/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/50846/9861/5698/5692/5713/5710/5719/6233/27248/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 57 Human_SARS_coronavirus_2 R-HSA-5655253 Signaling by FGFR2 in disease 43/7348 43/10654 1.110739388361621e-7 6.740710279585117e-7 2.9004172869799733e-7 5295/4893/2250/5335/5431/5435/5433/5439/2885/2252/2253/3845/3265/5290/8823/8074/5438/2249/2248/2247/2246/2251/2963/5434/5436/2263/2962/6654/2549/5432/22916/8822/5440/5430/8817/5441/2254/4686/26281/10818/5437/2255/27006 43 Human_SARS_coronavirus_2 R-HSA-69620 Cell Cycle Checkpoints 241/7348 293/10654 1.236277687729902e-7 7.470498506196929e-7 3.2144332141605197e-7 5689/55839/11130/9134/83990/11065/6249/5682/9156/57060/9735/1763/7531/7486/7321/5526/10971/8697/9212/5982/7533/2810/147841/348995/11200/143471/472/57122/5705/1780/23122/5048/5709/4174/5695/57405/8655/84515/23279/4194/4998/5711/2491/4683/10926/5683/990/1060/165918/5699/5702/8900/51529/29945/8924/11004/51434/55388/672/9184/5518/6117/29882/7334/5001/23332/25909/7465/51230/10726/81930/55746/5696/83695/5691/7314/996/5515/5718/6118/79682/10403/23594/25936/5700/122706/5707/51588/51720/3619/23198/63967/898/64105/7534/332/5528/993/890/983/51433/9861/79902/3796/9656/5519/81565/5698/5692/5985/5713/91687/119504/11243/4175/5710/7157/5984/7324/83540/5719/64682/6233/7514/7158/54820/6396/64946/9793/5884/5810/140735/4999/220134/4172/4928/5903/5000/8318/246184/55055/51512/1029/80776/1783/401541/7532/79172/4173/5706/9133/79980/6232/580/8881/891/5501/641/5714/54821/6119/9183/3364/10524/5688/1062/699/5687/5708/22919/5529/51143/1111/10393/5704/23595/7311/25906/5347/84643/5983/5694/4176/7529/1778/5516/1017/5905/81929/5684/5720/54908/55143/5883/5525/25946/1058/991/79019/10111/8317/348235/80152/5690/1063/8379/5717/1027/9491/23421/545/79023/55920/10197/7336/29086/1781/7316/10213/4085/1026/4171/55166/5715/7341/5701/5685/5686/995/79003/5527/5716/701/5932/9025/79184/57551/7156/5693/5721/4193 241 Human_SARS_coronavirus_2 R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 50/7348 51/10654 1.3491999981469256e-7 8.11816509523299e-7 3.4931135450343703e-7 51807/347688/10381/7278/1780/5048/8655/84516/832/636/7846/2590/81027/56894/51164/79861/23299/8398/5870/10376/10540/140735/84617/2589/11258/1783/10382/93661/55860/830/7277/10671/1639/347733/51143/10383/84790/5049/7280/829/22931/1778/5321/5050/112714/1781/22930/25782/10121/51560 50 Human_SARS_coronavirus_2 R-HSA-5619084 ABC transporter disorders 72/7348 77/10654 1.4894874388134462e-7 8.924301857975478e-7 3.8399809974762356e-7 5689/6833/5682/143471/91319/5705/5709/5695/64240/5711/5683/5699/6400/3767/5702/51009/5696/5691/7314/5718/5700/122706/5707/10956/79139/91445/64241/23198/9861/5698/215/5692/5713/5710/5719/10613/6233/27248/10058/6048/5706/19/335/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/1244/7316/10213/7415/5715/5701/5685/5686/5826/5716/21/368/5693/5721 72 Human_SARS_coronavirus_2 R-HSA-375280 Amine ligand-binding receptors 42/7348 42/10654 1.6133542826845788e-7 9.54511696952299e-7 4.107107577149028e-7 1816/83551/3363/155/3354/3360/153/319100/1131/1812/3361/134864/1129/1132/1814/3362/1813/146/3357/3352/148/150/4935/9287/134860/11255/147/3350/151/3356/1128/3358/1133/3269/9038/152/3355/3351/1815/154/3274/59340 42 Human_SARS_coronavirus_2 R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 42/7348 42/10654 1.6133542826845788e-7 9.54511696952299e-7 4.107107577149028e-7 2788/2740/11069/3709/9495/2782/8826/2787/10411/5567/3745/10681/112/5573/111/2792/2785/2783/2784/3710/2791/5568/5566/2641/2786/5577/3747/54331/5575/59345/51764/94235/114/3708/3790/55970/2778/2793/5576/26251/5906/2790 42 Human_SARS_coronavirus_2 R-HSA-3928662 EPHB-mediated forward signaling 42/7348 42/10654 1.6133542826845788e-7 9.54511696952299e-7 4.107107577149028e-7 71/1947/2051/10094/2050/2047/2534/9475/1948/8976/6093/8997/3265/5879/1072/10093/5921/6453/2902/6714/7525/10109/64283/2904/5747/7074/1949/2049/10092/4067/998/2048/10097/387/60/5058/3984/3985/6383/10552/10096/10095 42 Human_SARS_coronavirus_2 R-HSA-9007101 Rab regulation of trafficking 110/7348 124/10654 1.7952279745625773e-7 1.0576884816797851e-6 4.5510603916542536e-7 5869/116442/126003/7531/22878/1122/54453/10981/83874/5861/5866/23011/9610/60684/3257/414918/51762/51552/55357/9230/83452/126432/201475/5874/79961/221960/2665/79090/125058/58485/4943/5868/128637/81846/51622/7249/51209/5872/9827/80006/5870/8408/9909/10000/64786/51112/117177/83696/1121/23682/27095/6399/7109/4218/7879/2664/201627/26088/27342/23258/9363/84958/5864/10260/382/57679/81876/9135/259173/6305/51693/8567/208/5867/79890/22879/10133/11345/54734/57589/84315/7248/22931/51399/10890/23062/207/11337/51256/122553/79958/57706/8766/22930/55667/26130/25782/9367/51560/11021/5873/79735/81631/5878/11031/23163/338382/57465/89781/160518 110 Human_SARS_coronavirus_2 R-HSA-4608870 Asymmetric localization of PCP proteins 61/7348 64/10654 1.8781241274398967e-7 1.1019367287136985e-6 4.741453355144182e-7 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/57216/5696/5691/7314/5718/2535/5700/122706/5707/1856/8322/23198/9861/8321/5698/5692/5713/5710/5719/6233/7474/7855/7976/144165/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/50855/10197/64750/7316/10213/5715/5701/5685/5686/23513/5716/5693/5721 61 Human_SARS_coronavirus_2 R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 85/7348 93/10654 1.9204046629421834e-7 1.1145635353614942e-6 4.795784437124572e-7 8454/3725/9252/4790/1848/4792/177/1432/929/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/3665/351/387522/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/7335/4205/4793/3146/466/23291/6288/6285/5609/1385/5599/353376/148022 85 Human_SARS_coronavirus_2 R-HSA-975155 MyD88 dependent cascade initiated on endosome 85/7348 93/10654 1.9204046629421834e-7 1.1145635353614942e-6 4.795784437124572e-7 8454/3725/9252/4790/1848/4792/177/1432/929/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/3665/351/387522/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/7335/4205/4793/3146/466/23291/6288/6285/5609/1385/5599/353376/148022 85 Human_SARS_coronavirus_2 R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 49/7348 50/10654 1.9232920977949405e-7 1.1145635353614942e-6 4.795784437124572e-7 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 49 Human_SARS_coronavirus_2 R-HSA-69541 Stabilization of p53 55/7348 57/10654 2.108358258507812e-7 1.216823909195937e-6 5.235794085574718e-7 5689/5682/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/51230/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721/4193 55 Human_SARS_coronavirus_2 R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 93/7348 103/10654 2.2513352458785453e-7 1.294060177915554e-6 5.56812910619512e-7 5295/374/3643/2250/5291/5526/7039/3082/941/2064/145957/2534/9965/2264/3630/3654/9542/2885/8396/8660/5518/2252/2253/5879/5515/23396/1839/5290/3667/6801/8823/2065/3815/5594/2069/8074/79837/8395/2260/5528/2249/6714/2099/2248/5519/2247/5880/7409/2246/2251/5154/3932/8394/5781/940/2263/4233/8503/5159/29851/3084/5529/7189/9365/10718/5293/1956/2549/5595/5516/8822/685/5305/5525/207/8817/4615/2100/2254/152831/1950/26281/10818/2261/2255/391/2066/27006/5527/5155/4254/5296/5156 93 Human_SARS_coronavirus_2 R-HSA-5654743 Signaling by FGFR4 41/7348 41/10654 2.343304913388721e-7 1.3360617530369561e-6 5.748855008228697e-7 5295/4893/5335/8569/9965/2264/2885/5518/2253/3845/3265/7314/5515/5290/8823/5594/8074/2249/6714/2247/6233/2246/2251/5781/6464/673/6654/7311/2549/5595/5516/8822/10253/8817/10817/2254/7316/152831/26281/10818/867 41 Human_SARS_coronavirus_2 R-HSA-8875878 MET promotes cell motility 41/7348 41/10654 2.343304913388721e-7 1.3360617530369561e-6 5.748855008228697e-7 3675/5908/3082/1280/1289/3688/3910/1290/3908/2885/1399/5879/255631/3918/3911/284217/6714/2335/64759/3909/84951/1302/85440/5747/1277/3912/4233/2889/3913/2549/85301/3915/1301/1281/3673/3914/1398/5906/50509/1278/10319 41 Human_SARS_coronavirus_2 R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 84/7348 92/10654 2.5593349989847027e-7 1.453373368901353e-6 6.253627687225357e-7 8454/3725/9252/4790/1848/4792/177/1432/929/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/351/387522/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/7335/4205/4793/3146/466/23291/6288/6285/5609/1385/5599/353376/148022 84 Human_SARS_coronavirus_2 R-HSA-6811440 Retrograde transport at the Trans-Golgi-Network 48/7348 49/10654 2.7405412994626433e-7 1.550050158976071e-6 6.669612088797507e-7 400/60592/8674/3482/9382/10228/6293/8675/2800/339122/60560/7110/10618/55275/51209/10466/23647/9827/22836/5870/79571/91949/4074/2803/8677/10139/51542/22796/8775/9712/10244/9648/90196/57589/25839/84316/83548/63908/738/9367/10226/9341/57511/51560/8774/143187/4905/84342 48 Human_SARS_coronavirus_2 R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 70/7348 75/10654 2.762056322489372e-7 1.5559950756972e-6 6.695192092257737e-7 5295/374/2250/5291/7039/3082/941/2064/145957/2534/9965/2264/9542/2885/8660/2252/2253/5879/1839/5290/3667/6801/8823/2065/3815/2069/8074/2260/2249/6714/2099/2248/2247/5880/7409/2246/2251/5154/3932/5781/940/2263/4233/8503/5159/29851/3084/9365/10718/5293/1956/2549/8822/685/8817/2100/2254/152831/1950/26281/10818/2261/2255/391/2066/27006/5155/4254/5296/5156 70 Human_SARS_coronavirus_2 R-HSA-3371453 Regulation of HSF1-mediated heat shock response 65/7348 69/10654 2.8065759147597865e-7 1.5748009299485467e-6 6.776110604557882e-7 23165/6782/573/7531/9530/348995/472/57122/3313/23511/3305/23279/259217/23225/3309/9531/3306/27000/9972/23411/8021/6117/3312/55746/51182/3303/6118/5594/3308/10049/3337/10762/9261/79902/9883/2932/6396/129401/3297/4928/5903/55706/7175/4927/6119/57805/3310/7266/8086/3304/5595/81929/9631/116835/545/79023/23636/10808/53371/9532/9688/6767/22824/9529/8480 65 Human_SARS_coronavirus_2 R-HSA-5674135 MAP2K and MAPK activation 40/7348 40/10654 3.403371421826486e-7 1.902121419155198e-6 8.184517086813851e-7 4893/71/84292/5908/22866/5605/5037/2244/54756/3690/408/5894/8826/4140/3845/3265/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/28956/283455/3674/409/673/7450/60/7529/5595/5604/54518/10256/8649/5906 40 Human_SARS_coronavirus_2 R-HSA-187037 Signaling by NTRK1 (TRKA) 74/7348 80/10654 3.4446420524222147e-7 1.9176078197342566e-6 8.251152533361128e-7 5295/9252/4893/5335/5291/1848/1785/117/5605/5898/1432/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5515/161/5290/3667/5899/1849/5594/5528/9261/6714/5519/5598/4208/4914/6195/1213/1211/5600/1175/6300/1173/116/6464/135/160/673/6774/26052/7867/10126/2889/6654/5900/387/7529/5595/25759/5516/1845/5604/4205/57498/10818/466/53358/4803/1398/1385/5906/5296 74 Human_SARS_coronavirus_2 R-HSA-112399 IRS-mediated signalling 47/7348 48/10654 3.903402785076646e-7 2.1644751129797555e-6 9.313382083691648e-7 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/2246/2251/117145/5781/30849/5170/2322/5140/2263/208/9365/6654/2549/8822/8817/2254/152831/5289/26281/10818/2261/2255/27006/5296 47 Human_SARS_coronavirus_2 R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 78/7348 85/10654 4.0444583511585196e-7 2.2339312923977136e-6 9.612240653657996e-7 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/5934/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/1163/1019/5706/286826/4331/5714/5688/5687/5708/1874/208/5704/51343/7311/5694/1017/5684/994/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1026/5715/5701/5685/5686/5716/1022/5693/5721 78 Human_SARS_coronavirus_2 R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 53/7348 55/10654 4.1534292810487723e-7 2.285194164748235e-6 9.832816401581775e-7 51807/347688/10381/7278/1780/3305/8655/84516/832/7846/81027/3306/3312/51164/3303/79861/3337/10376/3301/10540/140735/84617/5241/11258/1783/10382/93661/10294/55860/830/7277/10671/1639/2908/347733/51143/3326/367/10383/84790/3304/7280/10728/829/1778/112714/1781/2289/10121/3320/10963/55466/2288 53 Human_SARS_coronavirus_2 R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 86/7348 95/10654 4.893605769469283e-7 2.671644230899446e-6 1.149564777383965e-6 8454/3725/9252/4790/1848/10333/4792/59307/177/1432/929/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/387522/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/7335/4205/4793/3146/466/23291/6288/6285/5609/948/1385/5599/7097 86 Human_SARS_coronavirus_2 R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 86/7348 95/10654 4.893605769469283e-7 2.671644230899446e-6 1.149564777383965e-6 8454/3725/9252/4790/1848/10333/4792/59307/177/1432/929/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/387522/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/7335/4205/4793/3146/466/23291/6288/6285/5609/948/1385/5599/7097 86 Human_SARS_coronavirus_2 R-HSA-977444 GABA B receptor activation 39/7348 39/10654 4.942781179735691e-7 2.677813252163321e-6 1.1522192062461098e-6 2788/3760/2770/2550/107/9568/3762/2774/2782/3765/3773/2773/2787/112/111/2792/2785/2783/2784/2771/196883/3759/115/113/3763/2786/3772/109/54331/3761/3766/94235/114/108/55970/346562/2793/3768/2790 39 Human_SARS_coronavirus_2 R-HSA-991365 Activation of GABAB receptors 39/7348 39/10654 4.942781179735691e-7 2.677813252163321e-6 1.1522192062461098e-6 2788/3760/2770/2550/107/9568/3762/2774/2782/3765/3773/2773/2787/112/111/2792/2785/2783/2784/2771/196883/3759/115/113/3763/2786/3772/109/54331/3761/3766/94235/114/108/55970/346562/2793/3768/2790 39 Human_SARS_coronavirus_2 R-HSA-674695 RNA Polymerase II Pre-transcription Events 77/7348 84/10654 5.410914739466616e-7 2.920241771605265e-6 1.2565322295748106e-6 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/11198/904/51497/4300/80349/2959/404672/5438/83860/2068/1025/23168/55677/6883/7936/6829/2957/123169/25920/85403/2963/5434/5436/9646/6878/79577/4331/8148/2966/2962/4298/54457/8812/905/2071/27125/6880/6908/6882/2961/5432/22916/55840/6877/6917/5440/902/6830/5430/6749/5441/7469/4686/6872/6879/9150/54623/2958/5437/6827/2968/138474/1022/8178 77 Human_SARS_coronavirus_2 R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 117/7348 134/10654 5.44748655571305e-7 2.9288007565696784e-6 1.2602150206932733e-6 5579/2153/7042/5175/3959/5578/5582/3082/29106/7423/3920/374354/2244/7114/3309/3690/2162/87/10487/7040/5874/54863/350/7043/967/5054/5099/1072/3699/7018/6678/5340/813/7094/7414/10490/83706/7044/6810/7123/6694/3671/7273/22927/1191/3273/27154/226/2335/1/5478/94121/22915/2266/7873/5154/7076/2243/801/805/928/351/51097/7424/2316/3674/5552/2157/7277/334/10447/10257/335/51706/308/78991/6403/197/81/9948/3481/54495/5473/8407/7450/29789/10916/139322/5005/7422/5004/5196/3827/1950/2621/5216/5768/710/6647/23052/5265/5345/54676/2/948/88/1675/5341/3479/5155/51368/808/213/5660/7057/5627/6814 117 Human_SARS_coronavirus_2 R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 52/7348 54/10654 5.82387953285644e-7 3.107797285698674e-6 1.3372342969804465e-6 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/8471/2246/2251/117145/5781/30849/5170/6464/2322/5140/2263/3481/208/9365/6654/2549/3480/8822/8817/2254/152831/5289/26281/10818/2261/2255/27006/3479/5296 52 Human_SARS_coronavirus_2 R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 113/7348 129/10654 5.824372565135422e-7 3.107797285698674e-6 1.3372342969804465e-6 8454/3725/9252/4790/7321/1848/1785/10333/4792/59307/177/1432/929/3654/6196/1759/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/23098/11035/8945/1326/5601/5606/8737/8767/5336/1849/29110/5594/4214/23118/841/8517/5528/7323/5970/7096/9261/5519/5598/4208/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/671/3665/351/387522/3684/330/51295/79155/8651/26052/7867/64127/5602/3656/57162/695/7189/7311/9641/6416/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/7335/4205/4793/5775/3146/7322/329/466/23291/6288/6285/5609/948/1385/5599/353376/7097/3689/148022 113 Human_SARS_coronavirus_2 R-HSA-5687128 MAPK6/MAPK4 signaling 81/7348 89/10654 6.02147470838888e-7 3.200889187090931e-6 1.377290218222704e-6 2308/5689/3725/5682/27327/143471/5705/5709/5695/4609/5711/5683/5699/5702/192669/8997/4343/5062/5696/5691/7314/5879/5718/5700/122706/5707/5567/23198/3337/983/9861/5698/5692/5713/5710/8555/896/5719/6233/7514/26523/5568/3315/5706/5597/5714/5566/5688/5687/5708/5063/998/5704/7311/5694/5058/27161/5684/5720/2309/10642/5690/57690/5717/9491/10197/192670/5596/8550/7316/10213/5715/5701/5685/5686/8556/23112/5716/8202/5693/5721 81 Human_SARS_coronavirus_2 R-HSA-1236975 Antigen processing-Cross presentation 89/7348 99/10654 6.732923216666803e-7 3.5656754413359025e-6 1.5342517718247241e-6 8773/5689/5682/3107/55176/811/143471/5705/10333/5709/5695/567/3693/3106/5711/5683/929/5699/5702/3551/5696/5691/7314/5718/10952/5700/122706/5707/23198/6892/8517/6810/1515/7096/9861/5698/5692/5713/5710/5719/6233/3685/1535/1514/4688/653361/6890/5706/9554/29927/50489/5714/5688/5687/5708/2923/695/5704/4012/7311/5694/8673/3105/23643/1147/5684/5720/5690/5717/9491/10197/7099/4615/23480/6891/7316/10213/5715/5701/9341/5685/5686/948/1520/5716/7097/1536/5693/5721 89 Human_SARS_coronavirus_2 R-HSA-420499 Class C/3 (Metabotropic glutamate/pheromone receptors) 38/7348 38/10654 7.178189467041587e-7 3.7872984725361203e-6 1.629612534151625e-6 50833/5726/2550/50832/259294/2912/259295/9568/2911/2914/259296/259289/50835/338398/2916/259293/54429/222545/80835/50840/2913/2918/50838/83756/259286/259287/50836/846/259290/80834/259292/50834/259285/2917/50831/50839/50837/2915 38 Human_SARS_coronavirus_2 R-HSA-69202 Cyclin E associated events during G1/S transition 76/7348 83/10654 7.231572562493131e-7 3.801280149949921e-6 1.6356286210608608e-6 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/5934/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/1163/1019/5706/286826/4331/5714/5688/5687/5708/1874/208/5704/7311/5694/1017/5684/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1026/5715/5701/5685/5686/5716/1022/5693/5721 76 Human_SARS_coronavirus_2 R-HSA-2262752 Cellular responses to stress 377/7348 479/10654 7.460867800363995e-7 3.9072840998943294e-6 1.681240385423154e-6 1912/23165/5689/3725/6782/9134/2077/11065/573/4790/54468/5682/64344/7531/1915/7321/51807/817/6045/8697/9530/347688/23677/27327/80012/7295/5925/3091/348995/143471/472/10381/57122/5705/79813/9681/3576/7278/3313/1780/7001/23511/10312/5709/9978/2114/1869/5695/3305/8655/84516/1911/832/26277/23279/4194/1031/5711/5928/1432/1387/4683/10325/7846/259217/23225/5683/3309/23512/57332/5699/126374/25994/7428/5702/192669/9531/81027/8900/51529/4001/29945/8131/2056/51434/2475/1032/3306/27000/1030/6196/9972/10670/534/23411/8021/4343/6117/10587/6197/29882/3312/4217/54386/3569/64121/55746/5696/5691/7296/7314/51164/996/51182/5718/818/3303/7014/6118/51606/5601/79861/2876/5606/7027/526/5700/122706/5707/2146/155066/9550/2936/9114/5594/3308/84335/23198/898/10049/10013/100532731/3337/10762/847/7323/890/5970/9261/6667/525/51433/9861/79902/5598/9883/2932/84733/9973/529/5698/5692/5713/2877/119504/10376/6195/5710/3301/533/10540/7157/7324/5719/64682/6233/2353/538/8726/6396/1535/129401/5600/523/201163/26523/528/405/5608/3297/57521/140735/768/6015/28956/84617/4928/4688/1019/5903/55706/7175/653361/5241/11258/9448/246184/112399/1029/1783/25828/8535/84962/10382/93661/5931/58528/10294/55860/830/7013/7277/1051/1410/5706/10671/8881/527/6774/1639/5714/4927/7867/64223/6119/10524/5688/5687/57805/3281/3310/2908/347733/5708/5602/7266/25824/6009/51143/816/6648/8086/10393/1870/5704/3326/55004/51343/7311/367/25906/3397/2034/57634/10383/84790/55662/648/5694/3304/23466/3456/2113/6416/10641/257202/7280/10728/829/2880/23523/5595/1778/1017/815/25913/81929/5684/5720/9631/3159/7290/23334/116835/10111/79726/475/7422/5690/57690/6649/5717/1027/9491/545/79023/23636/10197/192670/10808/153129/112714/3490/8550/1781/7316/10213/127124/10935/53371/1026/9532/54205/2289/9588/9688/10121/7415/1871/6647/8994/7322/5715/2882/5701/90423/84219/112398/245972/5685/8649/3320/8992/65057/5686/2033/1021/6767/25842/493869/8453/50507/23135/10963/22824/23112/5609/10542/5716/245973/9529/5599/54583/5052/1536/5693/5721/55466/2288/5034/8480/10919/51382/2950/4193/9296/23043 377 Human_SARS_coronavirus_2 R-HSA-2408522 Selenoamino acid metabolism 104/7348 118/10654 8.327174626142633e-7 4.344880044784385e-6 1.8695307570054154e-6 6158/6138/6227/6206/6234/6191/6128/6132/6129/9255/6176/6224/6146/6154/6202/6169/1491/6175/6218/6173/6167/116832/6192/6156/6143/6139/3921/6208/6170/7296/6203/6147/4143/191/6222/2936/27232/6134/60678/6155/6231/6142/9061/23521/6207/6233/51091/140032/6188/200916/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/22928/7311/6223/25873/9045/6187/9060/6168/6157/6137/6144/9349/4736/51121/6159/9521/6217/6152/51065/6141/6123/875/6164/79048/6209/11224/6165/6130/6204/6228/51540/7965/6124/6189/6135/6201/6161/118672/6133 104 Human_SARS_coronavirus_2 R-HSA-9020702 Interleukin-1 signaling 92/7348 103/10654 8.935906353395292e-7 4.645357199890052e-6 1.9988211579963155e-6 8454/5689/4790/5682/8878/143471/5705/5709/9978/5695/4792/177/5711/5683/5699/5702/3654/7334/3551/5696/5691/7314/257397/5718/8945/1326/5700/122706/5707/8767/23198/23118/8517/5970/9861/5698/5692/5713/5710/10454/5719/6233/7850/5608/4791/351/387522/54472/5706/79155/5714/64127/5688/5687/5708/3656/57162/7189/5704/7311/5694/6416/28511/1147/5684/5720/6885/5604/4215/10392/5690/3553/5717/9491/6500/10197/4615/7316/10213/7335/4793/3146/5715/5701/23291/5685/5686/6288/6285/5716/5693/5721 92 Human_SARS_coronavirus_2 R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 61/7348 65/10654 9.893954048897353e-7 5.1245608150699114e-6 2.2050146289811727e-6 5982/5431/5435/9978/5433/2965/5439/2967/6117/10714/7314/6118/404672/3150/5438/3978/5985/2068/5984/6233/7874/5424/8451/10450/5434/5436/7515/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/2071/51426/7311/3980/5983/5432/56655/6917/5440/902/27339/5430/57804/5441/7316/5426/5437/2033/2968/56949/9716/5981/57461/1022 61 Human_SARS_coronavirus_2 R-HSA-190236 Signaling by FGFR 79/7348 87/10654 1.0595866335768507e-6 5.468085765976887e-6 2.3528277918072214e-6 5295/4893/2250/5335/54845/5431/5435/5433/8569/9965/5439/2264/7072/2885/7073/5518/2252/2253/3845/3265/23769/7314/5515/5290/8823/5594/8074/2260/5438/3185/2249/6714/2248/4670/2247/6233/2246/2251/200734/5781/5725/2963/5434/6464/5436/673/2263/2962/80004/9365/6654/7311/2549/5432/22916/5595/5516/8822/10253/5440/23543/5430/3178/8817/10817/5441/2254/4686/7316/152831/26281/10818/2261/867/5437/2255/27006/3187/161742 79 Human_SARS_coronavirus_2 R-HSA-3000178 ECM proteoglycans 70/7348 76/10654 1.1311879382855453e-6 5.8163627081300405e-6 2.502685658675771e-6 7042/256076/63923/1280/1289/7448/4684/3688/176/3693/3381/3910/1290/4038/3908/1605/1463/3690/3694/3679/8785/7040/1285/7043/63827/1311/5054/633/6678/375790/3911/1284/284217/1298/4148/2335/3909/1834/1288/3685/1292/1293/1291/7143/1286/1287/351/3674/1277/3912/3913/4060/7148/3371/1282/1299/3339/1634/3915/1462/1281/1297/3673/1758/8516/50509/3687/3680/131873/1278 70 Human_SARS_coronavirus_2 R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/7348 52/10654 1.1426782286266925e-6 5.8541558524570405e-6 2.5189474300008708e-6 5689/5682/143471/472/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Human_SARS_coronavirus_2 R-HSA-68886 M Phase 314/7348 395/10654 1.2162036984973896e-6 6.20834667752819e-6 2.671349943877983e-6 114791/10844/23165/5689/55839/11130/11065/440145/6249/5579/5682/9735/7531/1459/11190/7321/91754/203068/5526/54801/51807/8697/5578/9212/347688/10274/5861/5925/1460/147841/348995/79441/143471/10381/57122/5705/5116/7278/1780/23122/23511/5048/5709/5695/57405/8655/1457/23279/9702/5711/2491/10112/7846/23225/7840/5683/1060/5699/11064/5702/5520/81027/51529/4001/29945/11004/23133/51434/9184/9972/5518/55844/55835/29922/8021/29882/23332/84930/25909/10726/81930/55746/93323/5696/5691/7314/996/5515/5718/79682/10403/79861/64151/25936/55869/5700/122706/5707/1454/2801/5594/3619/23198/64105/23310/332/10762/10051/5528/983/8548/51433/9861/79902/3796/8615/79959/5519/9883/81565/221496/2029/7444/5698/5692/5713/80097/91687/119504/11243/10376/23397/5710/10540/85378/7324/2010/83540/64900/5719/64682/6233/7514/54930/54820/113130/9493/6396/129401/1453/27229/64946/9793/140735/220134/84617/4928/26271/5903/55706/7175/11258/22981/246184/55055/8636/80776/1783/401541/7532/55125/10382/79172/121441/7277/5706/9133/79980/25836/6232/23047/8881/9814/653784/5885/23354/891/5501/9738/1639/5714/55722/4957/4927/5566/54821/81876/9183/5688/1062/699/5687/7283/347733/5708/22919/8243/10426/5529/22994/51143/1069/8086/10393/79648/5577/5704/7311/25906/10383/5347/54892/84790/84643/80184/5694/22897/6418/5108/7112/10592/7280/10806/29781/5595/1778/5516/4000/115106/4926/5905/22995/55559/81929/5684/5720/54908/55143/9631/5525/10142/1058/991/79019/5862/348235/80152/5690/1063/8379/95681/5717/9491/140609/10783/23244/23421/79023/55920/23636/10735/10197/112714/23141/1781/7316/10213/80321/53371/26003/4085/9688/55166/10121/5715/84131/5701/5685/3320/8815/5686/79003/9126/9918/10733/23399/4751/9232/23592/9700/5527/27175/80254/5716/701/57551/9662/55142/64689/8481/5693/5721/55755/8480 314 Human_SARS_coronavirus_2 R-HSA-438064 Post NMDA receptor activation events 74/7348 81/10654 1.2875695432363202e-6 6.549004799050924e-6 2.817929556950372e-6 5563/4893/51807/817/347688/10381/7278/107/7846/81027/1741/6196/8874/6197/3845/3265/5879/5923/818/57554/79861/5567/5594/51422/5573/2902/6714/10376/6195/5613/2906/801/2891/4747/805/5170/84617/3838/2904/2890/10382/5568/7277/10645/5566/2905/5571/27330/347733/3084/816/5577/5562/10383/84790/5564/5565/5924/7280/5595/815/28964/5575/114/112714/5576/2903/4137/2066/1742/88/1385/808/8536 74 Human_SARS_coronavirus_2 R-HSA-8878166 Transcriptional regulation by RUNX2 106/7348 121/10654 1.2995878876056212e-6 6.5864418389761586e-6 2.834038102380868e-6 8454/8493/5689/7291/5682/5925/143471/5705/5709/9978/5695/9759/10413/4089/3549/5711/5683/5699/5702/5696/5691/7314/5718/25/6662/5700/122706/5707/5594/3280/23198/100526737/10013/632/2737/865/11059/983/6714/2099/9861/2932/6502/5698/10000/5692/5713/595/5710/5719/6233/7525/10432/4091/117581/1019/3958/5706/3678/1277/891/5714/6772/9464/2736/5688/5687/2908/5708/4488/208/5704/7311/367/860/5694/5595/57154/5684/8841/5720/23462/10273/207/5690/5717/9491/6500/4086/59269/10197/7316/10213/4094/1026/5715/5701/5685/5686/55294/861/5716/581/5693/5721/10891 106 Human_SARS_coronavirus_2 R-HSA-186797 Signaling by PDGF 55/7348 58/10654 1.3248029480676965e-6 6.690254887741867e-6 2.8787071578313104e-6 5295/4893/5335/5291/256076/1280/1289/6696/6776/5327/1290/2885/8440/9564/3845/1285/3265/1399/56034/5290/5340/1284/5921/6778/1298/6714/1292/5154/1293/5781/1291/1286/1287/80310/5782/6774/6772/2889/5159/7058/2886/6654/1282/4690/1299/5045/1281/1297/1398/5155/50509/5296/131873/7057/5156 55 Human_SARS_coronavirus_2 R-HSA-1268020 Mitochondrial protein import 60/7348 64/10654 1.3525714531972683e-6 6.806178059860986e-6 2.9285870011163933e-6 26519/131118/26520/3313/5009/10440/50/51142/25813/23203/9512/80273/3421/131474/90639/197257/134266/54927/3329/84269/100287932/10469/8604/1431/79145/9804/10531/51287/10245/7416/4714/293/1678/150274/4580/29090/10651/29928/401505/2395/10063/56942/10452/100188893/51025/400916/10165/56993/26521/100272147/26517/6901/92609/617/54543/1537/388753/2671/26515/291 60 Human_SARS_coronavirus_2 R-HSA-168638 NOD1/2 Signaling Pathway 36/7348 36/10654 1.5137232761113306e-6 7.5632675350580266e-6 3.254350208638085e-6 834/1432/5603/83737/3654/64170/7334/1540/3551/7314/257397/8767/23118/841/8517/7128/837/10454/6233/5600/6300/5608/387522/330/64127/3656/7189/7311/1147/6885/842/10392/835/7316/7335/329 36 Human_SARS_coronavirus_2 R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 36/7348 36/10654 1.5137232761113306e-6 7.5632675350580266e-6 3.254350208638085e-6 4893/71/5908/22866/5605/5037/2244/3690/408/5894/8826/4140/3845/3265/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/283455/3674/409/673/7450/60/7529/5595/5604/54518/10256/5906 36 Human_SARS_coronavirus_2 R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 49/7348 51/10654 1.598854853917128e-6 7.934062980242309e-6 3.4138974187300338e-6 5689/5682/143471/5705/5709/5695/5711/4946/5683/5699/5702/5696/5691/5718/1728/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/5706/4947/5714/5688/5687/5708/4953/5704/5694/5684/5720/5690/51686/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 49 Human_SARS_coronavirus_2 R-HSA-109704 PI3K Cascade 43/7348 44/10654 1.5991569656075373e-6 7.934062980242309e-6 3.4138974187300338e-6 5295/2250/5291/9965/2264/2885/8660/9846/2252/2253/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/2246/2251/117145/5781/30849/5170/2322/5140/2263/208/9365/2549/8822/8817/2254/152831/5289/26281/10818/2261/2255/27006/5296 43 Human_SARS_coronavirus_2 R-HSA-114608 Platelet degranulation 112/7348 129/10654 1.8153322467079007e-6 8.975104184772628e-6 3.86184040705619e-6 2153/7042/5175/3959/3082/29106/7423/3920/374354/2244/7114/3309/3690/2162/87/10487/7040/5874/54863/350/7043/967/5054/5099/1072/3699/7018/6678/5340/813/7094/7414/10490/83706/7044/7123/6694/3671/7273/22927/1191/3273/27154/226/2335/1/5478/94121/22915/2266/7873/5154/7076/2243/801/805/928/351/51097/7424/2316/3674/5552/2157/7277/334/10447/10257/335/51706/308/78991/6403/197/81/9948/3481/54495/5473/8407/7450/29789/10916/139322/5005/7422/5004/5196/3827/1950/2621/5216/5768/710/6647/23052/5265/5345/54676/2/948/88/1675/5341/3479/5155/51368/808/213/5660/7057/5627 112 Human_SARS_coronavirus_2 R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 77/7348 85/10654 1.8563057476932322e-6 9.082409436810486e-6 3.908012100406805e-6 8454/3725/9252/4790/1848/4792/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/81793/387522/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/28511/5595/5516/1147/1845/6885/5604/10392/6500/4615/7316/7335/4205/4793/3146/466/23291/6288/6285/5609/1385/5599 77 Human_SARS_coronavirus_2 R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 77/7348 85/10654 1.8563057476932322e-6 9.082409436810486e-6 3.908012100406805e-6 8454/3725/9252/4790/1848/4792/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/81793/387522/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/28511/5595/5516/1147/1845/6885/5604/10392/6500/4615/7316/7335/4205/4793/3146/466/23291/6288/6285/5609/1385/5599 77 Human_SARS_coronavirus_2 R-HSA-975871 MyD88 cascade initiated on plasma membrane 77/7348 85/10654 1.8563057476932322e-6 9.082409436810486e-6 3.908012100406805e-6 8454/3725/9252/4790/1848/4792/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/81793/387522/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/28511/5595/5516/1147/1845/6885/5604/10392/6500/4615/7316/7335/4205/4793/3146/466/23291/6288/6285/5609/1385/5599 77 Human_SARS_coronavirus_2 R-HSA-1474244 Extracellular matrix organization 243/7348 301/10654 2.191459818771598e-6 1.0685255806010482e-5 4.597690654264914e-6 3675/8174/3681/871/169044/6385/960/3696/7042/1511/5175/256076/5578/84171/63923/23385/92291/3383/1280/1289/84695/7448/6696/1300/4684/3688/1509/176/8076/7093/3693/3381/2192/4015/3910/1290/4038/1303/3908/836/2244/1605/1463/3690/3694/2200/87/84467/11096/8985/3679/6382/8785/7040/1285/9509/30008/22801/1296/7043/63827/1311/5118/5054/3655/255631/11117/826/8038/1294/3918/7373/633/4238/56999/6678/5340/375790/7412/5644/3911/823/1284/4680/284217/1305/2006/84034/1307/50848/3683/4313/3672/1756/1515/1298/102/5339/9510/84570/4148/5033/999/2247/827/2335/3909/1295/1834/1288/2266/3685/1292/5154/7076/2243/634/3791/1293/57642/7837/9672/90187/3691/5663/1302/1291/1508/1514/7077/1310/7143/1286/1287/8573/7276/1308/351/655/5352/4052/9644/91522/3674/3684/4811/64386/101/3384/83700/4318/3678/1277/3912/23127/59277/3695/5351/2201/85007/8751/3913/5654/652/3817/7092/4060/81578/4236/9507/7450/340267/4317/170690/5479/8515/3676/11095/7148/4319/51399/3371/1282/85301/64175/10491/4239/283208/1299/164656/1991/3339/8974/136227/5045/1634/140766/9508/79709/6383/831/4237/4016/649/667/3915/1301/1462/824/1281/1297/10516/3673/682/4017/1758/1088/3914/170692/2/1306/1520/8425/780/5155/8516/50509/2199/3687/3680/131873/2202/80781/7057/1278/3689/10319/977/961/58494/4323/5034/3682 243 Human_SARS_coronavirus_2 R-HSA-1227986 Signaling by ERBB2 48/7348 50/10654 2.2354522139487275e-6 1.0862300448534365e-5 4.673870065698552e-6 5295/4893/5335/26469/5578/2064/5753/145957/2534/9542/2885/3845/3265/7314/1839/5290/2065/2069/9101/6714/10000/6233/7525/5580/1729/6464/5782/10193/3084/2886/208/6654/10718/7311/387/1956/2549/11140/8065/685/10273/207/7316/1950/51072/3320/2066/5581 48 Human_SARS_coronavirus_2 R-HSA-5658442 Regulation of RAS by GAPs 63/7348 68/10654 2.3274499848821154e-6 1.1270596844600381e-5 4.849553321059347e-6 5689/4893/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/3845/3265/4763/5696/5691/7314/5718/8831/5700/122706/5707/23198/5921/9861/5698/5692/5713/5710/5719/6233/200734/9462/5706/84078/5714/5688/5687/5708/5704/7311/5694/5684/5720/153090/5690/5717/9491/10197/7316/10213/5715/8437/5701/5685/5686/5716/399473/5693/5721/161742 63 Human_SARS_coronavirus_2 R-HSA-429914 Deadenylation-dependent mRNA decay 53/7348 56/10654 2.5234609173660695e-6 1.217806736230588e-5 5.240023029414724e-6 5393/115024/80153/23404/26986/28960/219988/25904/1973/10767/55571/11340/57472/85456/29883/80349/51690/11157/1981/1977/23016/118460/9924/23644/5073/27258/4850/9652/255967/57819/246175/4848/23019/23658/1975/51010/56915/1974/167227/22894/1656/27257/4849/25804/10605/9337/55802/51013/196513/9775/54464/6499/54512 53 Human_SARS_coronavirus_2 R-HSA-170834 Signaling by TGF-beta Receptor Complex 67/7348 73/10654 2.7289514896046377e-6 1.3124957164288972e-5 5.6474542104958135e-6 892/7321/4738/9372/8239/9612/4609/4089/22938/23327/4088/5499/1030/9110/7040/904/7314/5054/7027/6497/51592/50848/7323/6667/4092/11171/7050/7046/5494/2280/9958/9040/6233/7514/1025/57530/5500/4221/5590/3726/5501/1024/60436/8812/1874/142/905/4087/7048/7311/387/57154/51377/10273/5045/50855/23370/64750/54778/7316/9611/5933/867/3065/6498/56288/23439 67 Human_SARS_coronavirus_2 R-HSA-5654727 Negative regulation of FGFR2 signaling 34/7348 34/10654 3.1915679641575027e-6 1.529788847904647e-5 6.582430984060792e-6 2250/8569/2885/5518/2252/2253/7314/5515/8823/5594/8074/2249/6714/2248/2247/6233/2246/2251/5781/673/2263/7311/5595/5516/8822/10253/8817/2254/7316/26281/10818/867/2255/27006 34 Human_SARS_coronavirus_2 R-HSA-442755 Activation of NMDA receptors and postsynaptic events 83/7348 93/10654 3.369114013536211e-6 1.609434869979798e-5 6.9251347788902195e-6 5563/4893/51807/817/347688/10381/7278/107/7846/81027/1741/6196/8874/6197/8825/3845/3265/5879/5923/818/57554/79861/5567/5594/51422/2892/5573/2902/116444/6714/10376/6195/5613/2906/801/2891/4747/805/5170/84617/3838/8573/2904/2890/10382/5568/7277/116443/10645/55327/5566/2905/5571/27330/347733/3084/816/5577/2893/5562/10383/84790/5564/5565/5924/7280/5595/64130/815/28964/5575/114/112714/5576/2903/4137/2066/9647/1742/88/1385/808/8536 83 Human_SARS_coronavirus_2 R-HSA-2022090 Assembly of collagen fibrils and other multimeric structures 57/7348 61/10654 3.4349473590608647e-6 1.6353587763340278e-5 7.036681104154456e-6 256076/84171/1280/1289/84695/1300/7093/4015/1290/1303/1285/1296/5118/3655/255631/1294/3918/7373/1284/1515/1298/5339/3909/1295/1288/1292/1293/7837/3691/1302/1291/1508/1514/1286/1287/1308/4318/1277/7092/1282/85301/1299/4016/649/667/1301/1281/1297/4017/3914/1306/1520/50509/131873/80781/1278/977 57 Human_SARS_coronavirus_2 R-HSA-9009391 Extra-nuclear estrogen signaling 70/7348 77/10654 4.027084574889544e-6 1.9108381170784613e-5 8.222023611042587e-6 5295/2788/374/4893/857/2770/7039/2782/3845/3265/8877/2773/2787/1839/5290/55625/6801/5594/2069/10681/4313/2792/6714/2099/10000/2785/595/2783/2784/2771/7514/2353/801/2791/805/5170/5590/6464/5747/1903/3315/4318/8503/2786/208/1956/3480/5595/596/685/54331/2309/59345/207/6722/1027/51764/94235/2100/1950/55970/346562/2793/3320/4846/1385/5296/808/3276/2790 70 Human_SARS_coronavirus_2 R-HSA-2871837 FCERI mediated NF-kB activation 74/7348 82/10654 4.267041610216466e-6 2.017925363493673e-5 8.682802502042308e-6 8454/5689/4790/5682/7321/143471/5705/5709/5695/4792/5711/5683/5699/5702/7334/3551/5696/5691/7314/257397/5718/8945/5700/122706/5707/23198/23118/8517/5970/9861/5588/5698/5692/5713/5710/10454/5719/6233/5170/387522/5706/8915/5714/5688/5687/4067/5708/7189/5704/7311/5694/997/1147/5684/5720/6885/5690/5717/9491/6500/10197/7316/10213/7335/7322/5715/5701/23291/5685/5686/5716/5693/5721/2207 74 Human_SARS_coronavirus_2 R-HSA-113418 Formation of the Early Elongation Complex 33/7348 33/10654 4.633990888218295e-6 2.148348562603498e-5 9.243992177360396e-6 5431/5435/5433/2965/5439/2967/51497/404672/5438/2068/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/7469/4686/9150/5437/6827/2968/1022 33 Human_SARS_coronavirus_2 R-HSA-163359 Glucagon signaling in metabolic regulation 33/7348 33/10654 4.633990888218295e-6 2.148348562603498e-5 9.243992177360396e-6 2788/107/2782/2787/5567/112/5573/111/2785/2783/2784/196883/115/2791/5568/2642/113/5566/2641/2786/5577/109/54331/5575/59345/51764/94235/114/108/55970/2778/5576/2790 33 Human_SARS_coronavirus_2 R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 33/7348 33/10654 4.633990888218295e-6 2.148348562603498e-5 9.243992177360396e-6 5431/5435/5433/2965/5439/2967/51497/404672/5438/2068/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/7469/4686/9150/5437/6827/2968/1022 33 Human_SARS_coronavirus_2 R-HSA-1839126 FGFR2 mutant receptor activation 33/7348 33/10654 4.633990888218295e-6 2.148348562603498e-5 9.243992177360396e-6 2250/5431/5435/5433/5439/2252/2253/8823/8074/5438/2249/2248/2247/2246/2251/2963/5434/5436/2263/2962/5432/22916/8822/5440/5430/8817/5441/2254/4686/26281/5437/2255/27006 33 Human_SARS_coronavirus_2 R-HSA-420092 Glucagon-type ligand receptors 33/7348 33/10654 4.633990888218295e-6 2.148348562603498e-5 9.243992177360396e-6 2788/2692/2740/2696/117/2782/2787/10681/2792/2785/2783/2784/2791/6343/9340/116/6344/2642/2641/2786/7432/54331/59345/7433/51764/94235/2695/55970/2778/2691/2793/7434/2790 33 Human_SARS_coronavirus_2 R-HSA-68962 Activation of the pre-replicative complex 33/7348 33/10654 4.633990888218295e-6 2.148348562603498e-5 9.243992177360396e-6 5422/4174/84515/4998/10926/990/55388/6117/5001/5558/6118/23594/5557/4175/23649/4999/4172/5000/8318/54107/4173/51053/6119/5427/81620/29935/23595/4176/56655/1017/8317/5426/4171 33 Human_SARS_coronavirus_2 R-HSA-180585 Vif-mediated degradation of APOBEC3G 51/7348 54/10654 4.788464326207753e-6 2.1983404406681048e-5 9.459099044935343e-6 5689/5682/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/60489/5706/5714/5688/5687/5708/5704/7311/5694/5684/8065/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Human_SARS_coronavirus_2 R-HSA-8848021 Signaling by PTK6 51/7348 54/10654 4.788464326207753e-6 2.1983404406681048e-5 9.459099044935343e-6 4893/1796/5770/2909/9021/27043/3091/116985/2064/5753/145957/9542/9564/3845/3265/5829/7314/5879/120892/1839/2065/2069/898/202559/5921/6421/595/6233/1019/10657/1793/6774/2908/3084/10718/7311/2034/387/1956/63916/1017/685/207/1027/7316/1950/867/2066/1398/9844/10656 51 Human_SARS_coronavirus_2 R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 51/7348 54/10654 4.788464326207753e-6 2.1983404406681048e-5 9.459099044935343e-6 4893/1796/5770/2909/9021/27043/3091/116985/2064/5753/145957/9542/9564/3845/3265/5829/7314/5879/120892/1839/2065/2069/898/202559/5921/6421/595/6233/1019/10657/1793/6774/2908/3084/10718/7311/2034/387/1956/63916/1017/685/207/1027/7316/1950/867/2066/1398/9844/10656 51 Human_SARS_coronavirus_2 R-HSA-166520 Signaling by NTRKs 89/7348 101/10654 5.350222423437506e-6 2.448289484382082e-5 1.0534588863045065e-5 5295/627/9252/4893/5335/5291/1848/1785/117/5605/5898/1432/2534/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5879/5515/161/5290/3667/5899/1849/5594/5528/9261/6714/5519/5598/4208/4914/6195/1213/1211/5600/1175/6300/5781/25920/1173/116/5800/6464/2904/135/7074/160/673/6774/26052/7867/10126/2889/6654/5900/387/2549/1020/7529/5595/25759/5516/1845/5604/5045/10817/4205/57498/5046/10818/466/53358/4803/1398/1385/5906/8851/5296/581 89 Human_SARS_coronavirus_2 R-HSA-5358346 Hedgehog ligand biogenesis 60/7348 65/10654 5.710684032887587e-6 2.6048087814525964e-5 1.1208065775921988e-5 5689/5682/143471/5705/5709/5695/3549/5711/5683/5699/6400/5702/51009/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/50846/9861/5698/5692/5713/5710/2262/5719/6233/27248/5706/84447/5714/5688/5687/5708/5704/7311/147111/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721/5034 60 Human_SARS_coronavirus_2 R-HSA-437239 Recycling pathway of L1 45/7348 47/10654 6.080485757945943e-6 2.7645681227445544e-5 1.1895484068684227e-5 9252/71/7430/51807/347688/1785/10381/7278/285643/7846/1808/81027/6456/5962/163/6196/1759/6197/8986/161/79861/5594/8650/6714/10376/6195/1213/1211/1175/1173/84617/10382/7277/4478/160/26052/27330/347733/3897/10383/24137/60/84790/7280/112714 45 Human_SARS_coronavirus_2 R-HSA-351202 Metabolism of polyamines 55/7348 59/10654 6.359890185505926e-6 2.88233484689275e-5 1.2402215004124243e-5 5689/5682/143471/5705/5709/5695/5711/4946/5683/5699/5702/5696/5691/5718/1728/5700/122706/5707/23198/6723/79814/9861/5698/5692/5713/5710/5719/196743/6303/5706/4947/5714/5688/5687/5708/4953/5704/262/5694/5684/5720/5690/51686/5717/9491/10197/10213/5715/6611/5701/5685/5686/5716/5693/5721 55 Human_SARS_coronavirus_2 R-HSA-5654741 Signaling by FGFR3 39/7348 40/10654 6.497976173819456e-6 2.9355074472142848e-5 1.263100799888228e-5 5295/4893/2250/5335/8569/2885/5518/2253/3845/3265/7314/5515/5290/8823/5594/8074/2249/6714/2247/6233/2246/5781/6464/673/6654/7311/2549/5595/5516/8822/10253/8817/10817/2254/7316/26281/10818/2261/867 39 Human_SARS_coronavirus_2 R-HSA-191859 snRNP Assembly 50/7348 53/10654 6.5863343241977555e-006 2.9565322966398812e-5 1.2721474484164755e-5 23165/6633/6606/8487/25929/348995/57122/23511/23279/23225/79084/9972/8021/55746/96764/10762/79902/9883/6636/10419/6396/129401/50628/4928/6635/5903/6632/55706/7175/6637/54960/4927/51808/8086/79833/22916/81929/11218/9631/79023/23636/10073/4686/53371/9688/1207/6634/8480/6628/79760 50 Human_SARS_coronavirus_2 R-HSA-194441 Metabolism of non-coding RNA 50/7348 53/10654 6.5863343241977555e-006 2.9565322966398812e-5 1.2721474484164755e-5 23165/6633/6606/8487/25929/348995/57122/23511/23279/23225/79084/9972/8021/55746/96764/10762/79902/9883/6636/10419/6396/129401/50628/4928/6635/5903/6632/55706/7175/6637/54960/4927/51808/8086/79833/22916/81929/11218/9631/79023/23636/10073/4686/53371/9688/1207/6634/8480/6628/79760 50 Human_SARS_coronavirus_2 R-HSA-392518 Signal amplification 32/7348 32/10654 6.728027776743405e-6 2.9729472738484924e-5 1.2792105443939764e-5 2788/64805/2770/2769/5028/1432/2782/2776/2773/2787/10681/2792/6714/2785/2783/2784/2771/2791/6915/2786/5321/54331/59345/51764/94235/55970/2767/346562/2793/9630/2790/10672 32 Human_SARS_coronavirus_2 R-HSA-397795 G-protein beta:gamma signalling 32/7348 32/10654 6.728027776743405e-6 2.9729472738484924e-5 1.2792105443939764e-5 2788/5331/2782/2787/10681/2792/146850/10000/5294/2785/2783/2784/2791/5170/23236/998/695/2786/208/387/5058/54331/59345/207/9459/51764/94235/5330/55970/2793/23533/2790 32 Human_SARS_coronavirus_2 R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 32/7348 32/10654 6.728027776743405e-6 2.9729472738484924e-5 1.2792105443939764e-5 2788/2149/2769/408/2768/2782/2776/2787/5594/10681/2792/6714/2785/2783/2784/2151/2791/2147/409/2786/5595/54331/59345/51764/94235/55970/2767/2793/9630/9002/2790/10672 32 Human_SARS_coronavirus_2 R-HSA-5673000 RAF activation 32/7348 32/10654 6.728027776743405e-6 2.9729472738484924e-5 1.2792105443939764e-5 4893/5526/817/5605/3717/4296/5894/5518/4140/3845/3265/5515/818/8844/5528/6714/5519/369/801/805/673/8315/5529/816/7529/5516/815/5604/5525/5527/808/5245 32 Human_SARS_coronavirus_2 R-HSA-69190 DNA strand elongation 32/7348 32/10654 6.728027776743405e-6 2.9729472738484924e-5 1.2792105443939764e-5 2237/1763/5982/5422/4174/84515/84296/6117/10714/5558/6118/64785/3978/5557/5985/4175/5984/23649/5424/4172/8318/4173/5425/5111/6119/51659/5983/4176/57804/9837/4171/5981 32 Human_SARS_coronavirus_2 R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 71/7348 79/10654 9.699912174178405e-6 4.27279620382812e-5 1.8385142602640167e-5 5982/5431/5435/9978/5433/10980/2965/5439/10987/2967/6117/10714/7314/6118/404672/3150/5438/3978/5985/10920/2068/5984/6233/7874/5424/8451/10450/5434/5436/7515/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/2071/51426/2873/7311/3980/8533/5983/5432/51138/56655/9318/6917/5440/902/27339/5430/57804/5441/7316/64708/5426/5437/2033/2968/56949/9716/5981/57461/1022/8178/50813 71 Human_SARS_coronavirus_2 R-HSA-5654733 Negative regulation of FGFR4 signaling 31/7348 31/10654 9.767915685710704e-6 4.2893890619860044e-5 1.8456538955020553e-5 8569/9965/2264/2885/5518/2253/7314/5515/8823/5594/8074/2249/6714/2247/6233/2246/2251/5781/673/7311/5595/5516/8822/10253/8817/2254/7316/152831/26281/10818/867 31 Human_SARS_coronavirus_2 R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 94/7348 108/10654 9.821558513976529e-6 4.299592488781056e-5 1.85004426302051e-5 5295/3605/7124/2308/7291/356/3593/246/9021/6624/3082/5743/3091/3383/6657/3576/3662/3688/4985/7133/4609/4988/3717/2162/6347/7040/3312/3569/4692/3596/3598/3592/7412/3911/4582/6367/6778/332/4313/3565/3934/5443/3718/598/2247/2335/595/7157/4128/2353/604/7076/51561/7297/9655/3566/7184/3684/4318/3726/58480/301/6774/6772/8651/1901/79923/112744/3716/240/6356/3586/596/2309/3561/207/5292/5451/7422/3553/2625/3597/1026/3320/4843/6288/948/6935/3687/7431/3162/1278/4170/3689 94 Human_SARS_coronavirus_2 R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 86/7348 98/10654 1.1348021176659099e-5 4.937262136552605e-5 2.124423073719501e-5 8454/3725/9252/4790/1848/10333/4792/59307/177/1432/929/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/387522/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/7335/4205/4793/3146/466/23291/6288/6285/5609/948/1385/5599/7097 86 Human_SARS_coronavirus_2 R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 86/7348 98/10654 1.1348021176659099e-5 4.937262136552605e-5 2.124423073719501e-5 8454/3725/9252/4790/1848/10333/4792/59307/177/1432/929/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/351/387522/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/28511/5595/5516/23643/1147/1845/6885/5604/10392/6500/7099/4615/7316/7335/4205/4793/3146/466/23291/6288/6285/5609/948/1385/5599/7097 86 Human_SARS_coronavirus_2 R-HSA-4615885 SUMOylation of DNA replication proteins 43/7348 45/10654 1.1796943664622428e-5 5.116833847170587e-5 2.2016898411855876e-5 23165/9212/348995/6613/57122/23511/6790/23279/23225/9972/6612/8021/55746/7150/51588/3619/7153/332/10762/79902/9883/7155/6396/129401/4928/5903/55706/7175/5111/4927/8086/7329/5905/81929/55143/9631/79023/23636/53371/9688/7341/10401/8480 43 Human_SARS_coronavirus_2 R-HSA-167172 Transcription of the HIV genome 66/7348 73/10654 1.2352274090299922e-5 5.325035232830515e-5 2.2912754891506276e-5 6884/6875/6874/5431/5435/5433/2960/8732/2965/5439/6873/6881/2967/51616/11198/904/51497/2959/404672/5438/83860/2068/1025/6883/7936/6829/2957/25920/2963/5434/5436/6878/4331/8148/2966/2962/54457/8812/905/2071/6880/6908/6882/2961/5432/22916/6877/6917/5440/902/5430/6749/5441/7469/4686/6872/8731/6879/9150/2958/5437/6827/2968/138474/1022/8178 66 Human_SARS_coronavirus_2 R-HSA-8939902 Regulation of RUNX2 expression and activity 66/7348 73/10654 1.2352274090299922e-5 5.325035232830515e-5 2.2912754891506276e-5 8454/5689/7291/5682/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/865/11059/2099/9861/2932/6502/5698/5692/5713/5710/5719/6233/5706/5714/6772/5688/5687/2908/5708/4488/5704/7311/860/5694/57154/5684/5720/10273/5690/5717/9491/6500/59269/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721/10891 66 Human_SARS_coronavirus_2 R-HSA-5620920 Cargo trafficking to the periciliary membrane 48/7348 51/10654 1.2421009974454444e-5 5.33839152093574e-5 2.2970224812780898e-5 55763/1260/1258/123016/1262/10576/60412/6010/54585/84100/2847/166379/84747/10575/9727/5310/8729/11336/117177/378/56623/4218/6102/582/6753/585/5147/50807/5311/583/403/22948/55770/23265/10694/6608/10640/27031/7203/8766/149371/6950/55212/200894/54536/92482/129880/27241 48 Human_SARS_coronavirus_2 R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 30/7348 30/10654 1.418069639860487e-5 6.039609851694965e-5 2.5987452499662703e-5 56852/5982/9978/57599/6117/10714/7314/51514/6118/5985/5984/6233/5424/8451/54107/8450/5425/5111/6119/5427/1642/7311/5983/56655/57804/7320/7316/5426/7398/5981 30 Human_SARS_coronavirus_2 R-HSA-5654696 Downstream signaling of activated FGFR2 30/7348 30/10654 1.418069639860487e-5 6.039609851694965e-5 2.5987452499662703e-5 5295/4893/2250/5335/2885/2252/2253/3845/3265/5290/8823/8074/2249/2248/2247/2246/2251/5781/6464/2263/6654/2549/8822/8817/10817/2254/26281/10818/2255/27006 30 Human_SARS_coronavirus_2 R-HSA-8874081 MET activates PTK2 signaling 30/7348 30/10654 1.418069639860487e-5 6.039609851694965e-5 2.5987452499662703e-5 3675/3082/1280/1289/3688/3910/1290/3908/255631/3918/3911/284217/6714/2335/3909/1302/5747/1277/3912/4233/3913/85301/3915/1301/1281/3673/3914/50509/1278/10319 30 Human_SARS_coronavirus_2 R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 81/7348 92/10654 1.5427701744939667e-5 6.550982062265671e-5 2.818780340943616e-5 6884/6875/5563/83990/9156/1763/1459/7486/6874/9212/5982/1460/11200/472/28996/1457/6790/4194/1432/4683/8900/6873/672/6881/51616/6117/11198/83695/7314/6118/51422/890/83860/5985/7157/5984/6233/5600/6883/5884/5810/26155/8445/204851/6878/580/641/8148/6119/3364/5571/10524/54457/6794/1111/7311/5562/6880/6908/5983/5564/6882/5565/1020/6877/1017/5883/10111/22974/6749/545/8550/7316/6872/6879/5932/8851/5300/7156/138474/4193 81 Human_SARS_coronavirus_2 R-HSA-5654732 Negative regulation of FGFR3 signaling 29/7348 29/10654 2.058613188074557e-5 8.689191187872907e-5 3.7388167249240975e-5 2250/8569/2885/5518/2253/7314/5515/8823/5594/8074/2249/6714/2247/6233/2246/5781/673/7311/5595/5516/8822/10253/8817/2254/7316/26281/10818/2261/867 29 Human_SARS_coronavirus_2 R-HSA-72086 mRNA Capping 29/7348 29/10654 2.058613188074557e-5 8.689191187872907e-5 3.7388167249240975e-5 5431/5435/5433/8732/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/4686/8731/5437/2968/1022 29 Human_SARS_coronavirus_2 R-HSA-168325 Viral Messenger RNA Synthesis 41/7348 43/10654 2.280073497964659e-5 9.566836576029756e-5 4.116453168276036e-5 23165/348995/57122/5431/23511/5435/5433/23279/23225/5439/9972/8021/55746/5438/10762/79902/9883/6396/129401/4928/2963/5434/5903/55706/7175/5436/4927/2962/8086/5432/81929/5440/9631/5430/79023/5441/23636/53371/9688/5437/8480 41 Human_SARS_coronavirus_2 R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 41/7348 43/10654 2.280073497964659e-5 9.566836576029756e-5 4.116453168276036e-5 2788/361/107/554/2782/2787/22841/5567/10681/112/5573/111/2792/2785/2783/2784/196883/115/2791/5568/359/113/5566/2786/5577/109/54331/5575/59345/51764/94235/114/108/8766/55970/2778/2793/5576/4645/551/2790 41 Human_SARS_coronavirus_2 R-HSA-5632684 Hedgehog 'on' state 75/7348 85/10654 2.6898046466433747e-5 1.1252614705188555e-4 4.841815900840457e-5 5689/5682/11127/1452/51684/143471/5705/8452/5709/9978/5695/3549/5711/5683/408/5699/5702/83737/6469/5696/5691/7314/5718/339745/5700/122706/5707/23198/2737/5727/8650/50846/9861/8405/5698/5692/5713/5710/5719/6233/374654/23288/409/79577/5706/5714/2736/5688/5687/5708/5704/7311/5694/57154/5684/5720/2735/6608/5690/5717/9491/10197/64750/132884/7316/10213/50937/5715/5701/5685/5686/5716/23432/5693/5721 75 Human_SARS_coronavirus_2 R-HSA-202040 G-protein activation 28/7348 28/10654 2.9883638984262602e-5 1.2391632118400974e-4 5.3319164478789274e-5 2788/2780/2770/2775/4988/2782/2773/2787/10681/5443/2792/2785/2783/2784/2771/2791/2781/2786/54331/59345/51764/94235/2779/5173/55970/346562/2793/2790 28 Human_SARS_coronavirus_2 R-HSA-350054 Notch-HLH transcription pathway 28/7348 28/10654 2.9883638984262602e-5 1.2391632118400974e-4 5.3319164478789274e-5 79718/9759/9612/22938/1387/6907/4853/9794/79885/2648/9734/55869/51564/55534/84441/10013/83933/4854/8850/3066/10046/10014/4855/4851/8841/9611/3065/3516 28 Human_SARS_coronavirus_2 R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 28/7348 28/10654 2.9883638984262602e-5 1.2391632118400974e-4 5.3319164478789274e-5 2788/2770/2782/2787/784/10681/112/111/2792/2785/2783/2784/2771/2791/9254/150/775/2786/54331/59345/776/51764/94235/55970/152/2793/783/2790 28 Human_SARS_coronavirus_2 R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 40/7348 42/10654 3.1650105150089784e-5 1.300966531460086e-4 5.597846014917961e-5 23165/348995/57122/23511/81608/23279/23225/9972/8021/55746/53981/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/7884/4927/10898/10482/51692/8086/22916/81929/9631/29894/79023/23636/4686/8189/53371/9688/10189/8480/55339 40 Human_SARS_coronavirus_2 R-HSA-168253 Host Interactions with Influenza Factors 40/7348 42/10654 3.1650105150089784e-5 1.300966531460086e-4 5.597846014917961e-5 3839/23165/348995/57122/23511/23279/23225/3836/9972/8021/7040/55746/402569/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/3841/293/4927/10898/3840/8086/3837/81929/9631/79023/23636/53371/9688/8480 40 Human_SARS_coronavirus_2 R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 40/7348 42/10654 3.1650105150089784e-5 1.300966531460086e-4 5.597846014917961e-5 2788/2780/1459/2770/1460/2775/10576/1457/2782/10574/10693/2773/2787/10575/10681/2792/2785/2783/2784/2771/2791/2781/5082/2786/22948/9628/10694/54331/59345/8787/51764/94235/2779/7203/908/55970/346562/2793/6950/2790 40 Human_SARS_coronavirus_2 R-HSA-73893 DNA Damage Bypass 45/7348 48/10654 3.1894303213300086e-5 1.3072041954668499e-4 5.624685662025157e-5 56852/5982/9978/25898/57599/6117/10714/55666/7314/51514/6118/9636/11201/5985/5984/6233/5424/8451/124739/54107/7706/8450/5425/5111/6119/83932/5427/1642/5429/9246/51426/7311/7318/5983/56655/57804/7320/7316/5426/9100/10459/7415/7398/5981/5980 45 Human_SARS_coronavirus_2 R-HSA-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle 34/7348 35/10654 3.697170030343813e-5 1.510924399683859e-4 6.50126035150205e-5 9761/811/6400/51009/7314/9695/5700/10956/79139/91445/11253/80267/6233/55741/23193/267/64772/7841/6048/821/55757/56886/10206/84447/2923/7311/55768/7844/7316/5589/7415/51035/11236/5887 34 Human_SARS_coronavirus_2 R-HSA-5621481 C-type lectin receptors (CLRs) 119/7348 142/10654 3.716126670527356e-5 1.5142948449929918e-4 6.515762825920861e-5 8454/5689/9252/4893/4790/5682/7321/9039/29108/143471/5705/5530/5709/5695/4792/3709/5711/1387/5683/2534/5699/5702/5894/64170/3845/7334/3265/3551/5062/5696/5691/7314/257397/5718/8945/4773/5700/122706/5707/5567/5336/4582/23198/23118/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/3710/801/4791/805/5170/387522/4772/338339/5568/4775/3384/5706/56667/6850/8915/5714/5566/170482/5688/5687/4067/5708/5063/7189/5704/30835/7311/5971/5694/5058/997/1147/5684/5720/6885/5690/3553/5532/5717/9491/6500/3708/10197/7316/10213/7335/10768/7322/5715/5701/23291/5685/5686/2033/200958/5716/808/5693/5721/2207 119 Human_SARS_coronavirus_2 R-HSA-5696398 Nucleotide Excision Repair 95/7348 111/10654 4.0826716479334424e-5 1.6588786523499677e-4 7.137883280416002e-5 10445/5982/6613/5431/5435/9978/5433/10980/2965/5439/10987/2967/6612/6117/7334/10714/7314/6118/83444/404672/3150/86/5438/3978/1643/29844/5985/10920/2068/5984/6233/8607/7874/5424/5886/8451/8554/10450/5434/5436/7515/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/142/2071/1069/7329/51426/2873/7311/3980/60/8533/5983/5432/51138/7528/56655/9318/6917/5440/902/27339/5430/57804/5441/7336/54778/7316/64708/5426/7341/4798/5437/79913/10401/2033/2968/56949/5887/9716/5981/57461/1022/8178/50813/7508 95 Human_SARS_coronavirus_2 R-HSA-8953897 Cellular responses to external stimuli 379/7348 493/10654 4.2602048826271066e-5 1.7260543564569426e-4 7.426929338436036e-5 1912/23165/5689/3725/6782/9134/2077/11065/573/4790/54468/5682/64344/7531/1915/7321/51807/817/6045/8697/9530/347688/23677/27327/80012/7295/5925/3091/348995/143471/472/10381/57122/5705/79813/9681/3576/7278/3313/1780/7001/23511/10312/5709/9978/2114/1869/5695/3305/8655/84516/1911/832/26277/23279/4194/1031/5711/5928/1432/1387/4683/10325/7846/259217/23225/5683/3309/23512/57332/5699/126374/25994/7428/5702/192669/9531/81027/8900/51529/4001/29945/8131/2056/51434/2475/1032/3306/27000/1030/6196/9972/10670/534/23411/8021/4343/6117/10587/6197/29882/3312/4217/54386/3569/64121/55746/5696/5691/7296/7314/51164/996/51182/5718/818/3303/7014/6118/51606/5601/79861/2876/5606/7027/526/5700/122706/5707/2146/155066/9550/2936/9114/5594/3308/84335/23198/898/10049/10013/100532731/3337/10762/847/7323/1465/890/5970/9261/6667/525/51433/9861/79902/5598/9883/2932/84733/9973/529/5698/5692/5713/2877/119504/10376/6195/5710/3301/533/10540/7157/7324/5719/64682/6233/2353/538/8726/6396/1535/129401/5600/523/201163/26523/528/405/5608/3297/57521/140735/768/6015/28956/84617/4928/4688/1019/5903/55706/7175/653361/5241/11258/9448/246184/112399/1029/1783/25828/8535/84962/10382/93661/5931/58528/10294/55860/830/7013/7277/1051/1410/5706/10671/8881/527/6774/1639/5714/4927/7867/64223/6119/10524/5688/5687/57805/3281/3310/2908/347733/5708/5602/7266/25824/6009/51143/816/6648/8086/10393/1870/5704/3326/55004/51343/7311/367/25906/3397/2034/57634/10383/84790/55662/648/5694/3304/23466/3456/2113/6416/10641/257202/7280/10728/829/2880/23523/5595/1778/1017/815/25913/81929/5684/5720/9631/3159/7290/23334/116835/10111/79726/475/4502/7422/5690/57690/6649/5717/1027/9491/545/79023/23636/10197/192670/10808/153129/112714/3490/8550/1781/7316/10213/127124/10935/53371/1026/9532/54205/2289/9588/9688/10121/7415/1871/6647/8994/7322/5715/2882/5701/90423/84219/112398/245972/5685/8649/3320/8992/65057/5686/2033/1021/6767/25842/493869/8453/50507/23135/10963/22824/23112/5609/10542/5716/245973/9529/5599/54583/5052/1536/5693/5721/55466/2288/5034/8480/10919/51382/2950/4193/9296/23043 379 Human_SARS_coronavirus_2 R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 27/7348 27/10654 4.3378422549618766e-5 1.7353474385292238e-4 7.466915949303145e-5 5431/5435/5433/8732/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/5440/902/5430/5441/8731/5437/2968/1022 27 Human_SARS_coronavirus_2 R-HSA-3000170 Syndecan interactions 27/7348 27/10654 4.3378422549618766e-5 1.7353474385292238e-4 7.466915949303145e-5 6385/5578/1289/7448/3688/3693/1290/3690/87/6382/7040/3655/2247/2335/3685/9672/3691/8573/1277/51399/3371/6383/1281/3673/50509/7057/1278 27 Human_SARS_coronavirus_2 R-HSA-5654716 Downstream signaling of activated FGFR4 27/7348 27/10654 4.3378422549618766e-5 1.7353474385292238e-4 7.466915949303145e-5 5295/4893/5335/9965/2264/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/2251/5781/6464/6654/2549/8822/8817/10817/2254/152831/26281/10818 27 Human_SARS_coronavirus_2 R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 27/7348 27/10654 4.3378422549618766e-5 1.7353474385292238e-4 7.466915949303145e-5 5431/5435/5433/8732/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/5440/902/5430/5441/8731/5437/2968/1022 27 Human_SARS_coronavirus_2 R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 44/7348 47/10654 4.356777515402224e-5 1.7353474385292238e-4 7.466915949303145e-5 8454/79718/892/3091/9978/9759/9612/4609/22938/1387/6907/9794/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/7091/8850/3066/6233/7089/7090/10046/1024/10014/7088/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 44 Human_SARS_coronavirus_2 R-HSA-4570464 SUMOylation of RNA binding proteins 44/7348 47/10654 4.356777515402224e-5 1.7353474385292238e-4 7.466915949303145e-5 1912/23165/6045/80012/348995/6613/57122/23511/3190/1911/23279/23225/57332/9972/8021/55746/51602/100532731/10762/79902/9883/84733/6396/129401/7703/6015/4928/5903/55706/7175/8535/4927/8086/7329/648/81929/9631/79023/23636/3183/53371/9688/7341/8480 44 Human_SARS_coronavirus_2 R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 39/7348 41/10654 4.388674963259231e-5 1.7431422466428518e-4 7.500455732595611e-5 23165/348995/57122/23511/81608/23279/23225/9972/8021/55746/53981/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10898/10482/51692/8086/22916/81929/9631/29894/79023/23636/4686/8189/53371/9688/10189/8480/55339 39 Human_SARS_coronavirus_2 R-HSA-1980143 Signaling by NOTCH1 65/7348 73/10654 4.831486716904173e-5 1.9136476800287117e-4 8.234112700488315e-5 8454/79718/892/113878/182/3091/23385/9978/9759/9612/4609/22938/1387/6907/408/83737/9794/57534/28514/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/7091/8650/102/5664/8850/8788/3066/6233/7089/5663/7090/142678/23220/409/10046/1024/10014/9148/7088/7311/51107/4851/8841/23462/6500/7316/9611/54492/2033/55294/3065/1840/54567/3516 65 Human_SARS_coronavirus_2 R-HSA-9612973 Autophagy 101/7348 119/10654 4.934124369624677e-5 1.9488413012986854e-4 8.385545091570314e-5 9927/51652/5563/2670/65018/1459/1915/27243/8878/1460/5116/55048/9474/8655/1457/51271/3043/3920/10325/29082/9776/55054/2475/84557/10670/3312/11315/64121/92421/7314/137492/64422/139341/25978/51160/60673/9821/51422/7249/10533/10013/91782/79720/192111/440738/6714/8408/89853/55669/6233/9804/30849/51001/57521/140735/28956/7405/79643/79065/22863/58528/8100/7416/1068/64223/5571/128866/6009/3326/55004/7311/5562/93343/11345/55626/7251/5564/5565/401505/7248/155382/11337/10452/1080/64419/153129/100188893/7316/5289/8678/56993/10226/8649/3320/81631/10542/23710/54543/200894/7431/23192 101 Human_SARS_coronavirus_2 R-HSA-446652 Interleukin-1 family signaling 117/7348 140/10654 5.5725595601152686e-5 2.19487443398412e-4 9.444185385564069e-5 8454/834/5689/5777/4790/5682/1511/26469/5783/27178/8878/143471/5705/11141/5709/9978/5695/4792/59307/177/5711/4088/5683/84867/5699/5702/3654/7334/3551/5696/5691/7314/3596/257397/5718/8945/1326/5700/122706/5707/8767/29110/23198/23118/8517/3565/5970/8809/9861/5698/5692/5713/5710/10454/5719/6233/7850/5781/5608/4791/351/5782/387522/54472/5706/79155/6774/5780/5714/64127/5688/5687/5708/3656/57162/5771/7189/5704/7311/240/5694/6416/28511/1147/5778/5684/5720/6885/5604/4215/10392/5690/3553/5717/9491/6500/25930/10197/4615/7316/10213/7335/4793/5775/3146/5715/5701/23291/5685/5686/6288/6285/5716/5599/5784/5693/5721 117 Human_SARS_coronavirus_2 R-HSA-165159 mTOR signalling 38/7348 40/10654 6.078586146676247e-5 2.3809198923546298e-4 1.0244708537042924e-4 5563/6198/29904/10325/2475/55437/10670/92335/64121/51719/84335/51422/7249/1981/5494/1977/1978/57521/28956/6194/58528/64223/5571/6794/6009/208/1975/55004/5562/5564/5565/7248/7529/207/153129/8649/10542/81617 38 Human_SARS_coronavirus_2 R-HSA-168276 NS1 Mediated Effects on Host Pathways 38/7348 40/10654 6.078586146676247e-5 2.3809198923546298e-4 1.0244708537042924e-4 3839/23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/402569/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/3841/4927/10898/3840/8086/3837/81929/9631/79023/23636/53371/9688/8480 38 Human_SARS_coronavirus_2 R-HSA-8986944 Transcriptional Regulation by MECP2 56/7348 62/10654 6.263847348881336e-5 2.4459276238413344e-4 1.0524426163777946e-4 627/2571/2290/79718/5770/817/9212/27327/6657/28996/9612/4988/6907/192669/4204/3654/4343/6750/28514/818/2572/54487/4208/2593/3066/26523/801/2891/805/2904/3930/54715/4233/6515/5566/1392/816/25942/27161/815/8841/5468/4986/57690/192670/9611/2874/2289/5775/2903/3064/5728/3065/23112/1385/808 56 Human_SARS_coronavirus_2 R-HSA-6803529 FGFR2 alternative splicing 26/7348 26/10654 6.296447348502445e-5 2.4459276238413344e-4 1.0524426163777946e-4 54845/5431/5435/5433/5439/7072/7073/5438/3185/4670/5725/2963/5434/5436/2962/80004/5432/22916/5440/23543/5430/3178/5441/4686/5437/3187 26 Human_SARS_coronavirus_2 R-HSA-77387 Insulin receptor recycling 26/7348 26/10654 6.296447348502445e-5 2.4459276238413344e-4 1.0524426163777946e-4 3643/535/50617/10312/3630/534/51606/526/537/155066/9550/9114/525/529/533/523/528/527/127124/23545/90423/245972/8992/245973/51382/9296 26 Human_SARS_coronavirus_2 R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 75/7348 86/10654 6.816577320368353e-5 2.6335082871587026e-4 1.1331555050828038e-4 5295/5335/122618/71/51517/5291/4651/2268/3709/10094/2534/8976/2885/5879/26999/25/1072/5290/10093/10006/5336/4771/5594/4644/8398/4641/6714/10810/7525/7410/5580/7409/23191/3710/10109/10787/5747/10451/1793/6850/10152/5337/10092/4650/4067/998/695/3326/10097/60/5058/63916/5595/3984/23646/4690/4627/10458/3708/919/3055/10552/10768/4620/8936/917/3320/1398/10096/7454/9844/5296/5581/5338/10095 75 Human_SARS_coronavirus_2 R-HSA-5628897 TP53 Regulates Metabolic Genes 75/7348 86/10654 6.816577320368353e-5 2.6335082871587026e-4 1.1331555050828038e-4 5563/7531/10971/9997/27327/7295/7533/2810/7001/6341/4514/10325/192669/2475/10670/4513/4343/64121/7296/9377/1329/2936/51422/7249/7534/1351/2821/10000/2877/7157/1337/50484/9167/26523/2744/57521/28956/4512/7532/1345/58528/84987/64223/5571/10128/25824/6009/8626/208/55004/5562/1340/4697/5564/5565/7248/7529/27161/27165/207/57690/192670/153129/2539/54205/143686/1350/8649/5728/23112/10542/1349/6834/1327/5052 75 Human_SARS_coronavirus_2 R-HSA-3928665 EPH-ephrin mediated repulsion of cells 47/7348 51/10654 7.11728166252719e-5 2.7421897195676964e-4 1.179919346318863e-4 71/2042/1947/1212/23385/2051/2045/2050/285220/2047/2534/1948/163/1759/5879/161/2046/4313/2041/102/6714/5664/1943/2043/7525/1942/7410/1213/1211/1175/5663/1173/7074/1949/1945/10451/4318/160/2049/8218/4067/2044/2048/60/51107/1946/1969 47 Human_SARS_coronavirus_2 R-HSA-373080 Class B/2 (Secretin family receptors) 82/7348 95/10654 7.177462928049056e-5 2.757862114201458e-4 1.1866629211705821e-4 2788/7478/2692/2740/11211/2696/117/799/3549/5741/2782/10267/6469/2787/2535/7476/133/7473/8322/10681/7471/5727/89780/7477/8323/2792/50846/7475/8321/5744/7481/2785/2783/2784/7482/7474/7479/7855/2791/10268/6343/7976/7480/80326/9340/116/6344/2642/79924/2641/1392/7483/2786/113091/51384/7432/7472/54331/59345/6608/7433/10266/7484/5745/51764/94235/2695/5746/1604/796/55970/2778/54361/2691/2793/797/7434/10203/3375/1395/1394/2790 82 Human_SARS_coronavirus_2 R-HSA-2559585 Oncogene Induced Senescence 32/7348 33/10654 7.373720820954702e-5 2.802806785169341e-4 1.2060018773378093e-4 2077/27327/5925/2114/1869/4194/1031/192669/1032/1030/4343/7314/7027/5594/6667/7157/6233/26523/1019/1029/1870/7311/3397/2113/5595/57690/192670/7316/1871/1021/23112/4193 32 Human_SARS_coronavirus_2 R-HSA-5654726 Negative regulation of FGFR1 signaling 32/7348 33/10654 7.373720820954702e-5 2.802806785169341e-4 1.2060018773378093e-4 2250/8569/2885/5518/2253/7314/5515/5594/8074/2260/2249/6714/2248/2247/6233/2246/2251/5781/673/9365/7311/5595/5516/8822/10253/2254/7316/26281/10818/867/2255/27006 32 Human_SARS_coronavirus_2 R-HSA-5694530 Cargo concentration in the ER 32/7348 33/10654 7.373720820954702e-5 2.802806785169341e-4 1.2060018773378093e-4 6811/374/10960/2153/10484/7039/9570/90411/3998/375056/9632/1294/81562/254263/51128/10175/10959/2348/2890/10802/2157/9554/966/149111/79748/9871/1075/10113/1522/5265/10972/10427 32 Human_SARS_coronavirus_2 R-HSA-9022692 Regulation of MECP2 expression and activity 32/7348 33/10654 7.373720820954702e-5 2.802806785169341e-4 1.2060018773378093e-4 2290/79718/817/9212/27327/28996/9612/6907/192669/4204/4343/818/3066/26523/801/805/3930/5566/816/25942/27161/815/8841/57690/192670/9611/2874/3064/3065/23112/1385/808 32 Human_SARS_coronavirus_2 R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 37/7348 39/10654 8.40930443907791e-5 3.187870369130339e-4 1.371688433974046e-4 9134/10528/10576/10574/6468/10564/54461/10693/8877/10575/898/10517/26985/26190/10238/7157/83752/26224/2629/8237/63971/6774/26272/26270/22948/84261/10694/8841/22803/7203/908/11328/6950/3801/55294/6499/26234 37 Human_SARS_coronavirus_2 R-HSA-1296041 Activation of G protein gated Potassium channels 25/7348 25/10654 9.139005717224146e-5 3.37403500891774e-4 1.451792030934604e-4 2788/3760/2550/9568/3762/2782/3765/3773/2787/2792/2785/2783/2784/3759/3763/2786/3772/54331/3761/3766/94235/55970/2793/3768/2790 25 Human_SARS_coronavirus_2 R-HSA-1296059 G protein gated Potassium channels 25/7348 25/10654 9.139005717224146e-5 3.37403500891774e-4 1.451792030934604e-4 2788/3760/2550/9568/3762/2782/3765/3773/2787/2792/2785/2783/2784/3759/3763/2786/3772/54331/3761/3766/94235/55970/2793/3768/2790 25 Human_SARS_coronavirus_2 R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 25/7348 25/10654 9.139005717224146e-5 3.37403500891774e-4 1.451792030934604e-4 11065/7321/8697/51529/29945/51434/9184/29882/7314/996/51433/119504/7324/64682/6233/246184/8881/10393/7311/25906/991/7316/4085/4751/701 25 Human_SARS_coronavirus_2 R-HSA-392451 G beta:gamma signalling through PI3Kgamma 25/7348 25/10654 9.139005717224146e-5 3.37403500891774e-4 1.451792030934604e-4 2788/2782/2787/10681/2792/146850/10000/5294/2785/2783/2784/2791/5170/2786/208/387/54331/59345/207/51764/94235/55970/2793/23533/2790 25 Human_SARS_coronavirus_2 R-HSA-400685 Sema4D in semaphorin signaling 25/7348 25/10654 9.139005717224146e-5 3.37403500891774e-4 1.451792030934604e-4 2909/388/2064/23365/79784/9475/4628/6093/10507/5879/27289/389/5364/10627/4233/387/4629/3984/4627/3985/10398/9826/4637/103910/6237 25 Human_SARS_coronavirus_2 R-HSA-418592 ADP signalling through P2Y purinoceptor 1 25/7348 25/10654 9.139005717224146e-5 3.37403500891774e-4 1.451792030934604e-4 2788/2769/5028/1432/2782/2776/2787/10681/2792/6714/2785/2783/2784/2791/2786/5321/54331/59345/51764/94235/55970/2767/2793/9630/2790 25 Human_SARS_coronavirus_2 R-HSA-5654700 FRS-mediated FGFR2 signaling 25/7348 25/10654 9.139005717224146e-5 3.37403500891774e-4 1.451792030934604e-4 4893/2250/2885/2252/2253/3845/3265/8823/8074/2249/2248/2247/2246/2251/5781/2263/6654/8822/8817/10817/2254/26281/10818/2255/27006 25 Human_SARS_coronavirus_2 R-HSA-5654708 Downstream signaling of activated FGFR3 25/7348 25/10654 9.139005717224146e-5 3.37403500891774e-4 1.451792030934604e-4 5295/4893/2250/5335/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/5781/6464/6654/2549/8822/8817/10817/2254/26281/10818/2261 25 Human_SARS_coronavirus_2 R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 25/7348 25/10654 9.139005717224146e-5 3.37403500891774e-4 1.451792030934604e-4 5982/6117/10714/7314/6118/3978/5985/5984/6233/5424/7515/54107/5425/5111/6119/5427/51426/7311/3980/5983/56655/57804/7316/5426/5981 25 Human_SARS_coronavirus_2 R-HSA-997272 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits 25/7348 25/10654 9.139005717224146e-5 3.37403500891774e-4 1.451792030934604e-4 2788/3760/2550/9568/3762/2782/3765/3773/2787/2792/2785/2783/2784/3759/3763/2786/3772/54331/3761/3766/94235/55970/2793/3768/2790 25 Human_SARS_coronavirus_2 R-HSA-5654736 Signaling by FGFR1 46/7348 50/10654 9.565691682174426e-5 3.5223666767173536e-4 1.5156167193796104e-4 5295/4893/2250/5335/8569/2885/5518/2253/3845/3265/23769/7314/5515/5290/5594/8074/2260/2249/6714/2248/2247/6233/2246/2251/200734/5781/6464/673/9365/6654/7311/2549/5595/5516/8822/10253/8817/10817/2254/7316/26281/10818/867/2255/27006/161742 46 Human_SARS_coronavirus_2 R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 31/7348 32/10654 1.0400444086369691e-4 3.8099036109136644e-4 1.6393391551463543e-4 51807/10381/7278/10576/7846/7411/81027/10574/10693/5201/79861/5204/10575/10471/10376/5202/84617/10382/7277/347733/10383/60/84790/22948/7280/10694/5203/112714/7203/908/6950 31 Human_SARS_coronavirus_2 R-HSA-917729 Endosomal Sorting Complex Required For Transport (ESCRT) 31/7348 32/10654 1.0400444086369691e-4 3.8099036109136644e-4 1.6393391551463543e-4 51652/27243/55048/51271/29082/27183/92421/7314/137492/25978/51160/8027/91782/79720/51534/89853/51510/9146/6233/79643/11267/128866/7311/93343/7251/51028/155382/7316/9525/10254/84313 31 Human_SARS_coronavirus_2 R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 50/7348 55/10654 1.0466692712963568e-4 3.824264469284363e-4 1.645518397414101e-4 834/4790/7295/29108/1432/10628/5603/83737/3654/64170/7334/1540/3551/7314/257397/8767/23118/841/8517/5970/7128/837/598/10454/6233/5600/6300/5608/4791/351/387522/9051/330/64127/3656/7189/3326/4210/7311/114548/1147/596/6885/842/10392/10910/835/7316/7335/329 50 Human_SARS_coronavirus_2 R-HSA-388841 Costimulation by the CD28 family 62/7348 70/10654 1.0566078167167498e-4 3.850627455766712e-4 1.6568619589318545e-4 5295/5777/5526/941/3115/3113/3117/2534/2885/2475/5518/3127/5062/5879/5515/1326/5290/5133/57761/3126/5528/9020/6714/5519/29126/10000/1445/916/7525/7409/3932/117145/5781/1493/940/253260/3120/5170/3123/3122/920/64223/8503/4067/29851/5063/5529/998/208/79109/3125/5058/5516/9402/5525/3119/207/919/915/917/5527/5296 62 Human_SARS_coronavirus_2 R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 58/7348 65/10654 1.0867120645727115e-4 3.95015645065762e-4 1.699687656130503e-4 3725/4436/5892/472/5431/5435/5433/2965/5439/672/2967/1386/11198/904/51497/2176/404672/5438/1643/9656/2177/2068/7157/1025/2353/7936/6829/25920/2963/5434/5436/4292/4331/2966/2962/8812/905/1111/2071/55215/5432/6917/5440/8621/902/5430/6749/545/5441/7469/5395/9150/5437/51755/6827/2968/1022/8178 58 Human_SARS_coronavirus_2 R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 41/7348 44/10654 1.1015855484710244e-4 3.9634655611654664e-4 1.705414348510117e-4 892/7321/8239/9612/4609/4089/22938/23327/4088/1030/904/7314/5054/7027/6497/51592/7323/6667/4092/7050/5494/6233/1025/4221/3726/1024/60436/8812/1874/142/905/4087/7311/64750/54778/7316/9611/5933/3065/6498/23439 41 Human_SARS_coronavirus_2 R-HSA-6811438 Intra-Golgi traffic 41/7348 44/10654 1.1015855484710244e-4 3.9634655611654664e-4 1.705414348510117e-4 6811/11311/9570/9382/10228/83452/27314/8675/10652/51272/9321/10466/9827/347517/91949/9267/1523/27128/22796/27333/9265/4121/8775/4124/54734/57589/9609/25839/83548/9950/63908/9527/9342/57511/8774/143187/4905/9266/375/84342/10905 41 Human_SARS_coronavirus_2 R-HSA-69231 Cyclin D associated events in G1 41/7348 44/10654 1.1015855484710244e-4 3.9634655611654664e-4 1.705414348510117e-4 8454/5925/1869/5753/1031/3717/5520/1032/1030/5518/7314/5515/25/7027/5934/6714/5519/6502/595/896/6233/1163/1019/1029/4331/4067/1874/1870/7311/5516/894/902/1027/6500/7316/1026/5933/1871/1021/1022/1028 41 Human_SARS_coronavirus_2 R-HSA-69236 G1 Phase 41/7348 44/10654 1.1015855484710244e-4 3.9634655611654664e-4 1.705414348510117e-4 8454/5925/1869/5753/1031/3717/5520/1032/1030/5518/7314/5515/25/7027/5934/6714/5519/6502/595/896/6233/1163/1019/1029/4331/4067/1874/1870/7311/5516/894/902/1027/6500/7316/1026/5933/1871/1021/1022/1028 41 Human_SARS_coronavirus_2 R-HSA-9006936 Signaling by TGF-beta family members 87/7348 102/10654 1.1263200040811853e-4 4.0421738217532894e-4 1.7392812245763432e-4 10272/892/7321/4738/9372/91851/130399/8239/9612/4609/4089/22938/23327/4088/5499/1030/9110/7040/10589/904/7314/5054/7027/11167/6497/51592/50848/7323/91/93/6667/4092/11171/7050/7046/92/94/5494/2280/9958/9040/6233/7514/1025/8928/57530/2658/4091/5500/4090/4221/4093/5590/9350/269/3726/5501/1024/60436/8812/1874/142/905/4087/7048/7311/387/57154/51377/10273/5045/50855/4086/23370/64750/659/54778/7316/9611/5933/867/3065/6498/657/56288/23439/10468 87 Human_SARS_coronavirus_2 R-HSA-3232142 SUMOylation of ubiquitinylation proteins 36/7348 38/10654 1.1619346459684132e-4 4.138477555162056e-4 1.7807191445571866e-4 23165/348995/57122/23511/23279/23225/7428/5371/9972/8021/55746/51588/10762/79902/9883/9063/6396/129401/8554/4928/5903/55706/7175/4927/8086/7329/81929/9631/79023/23636/53371/9688/7341/5987/8480/4193 36 Human_SARS_coronavirus_2 R-HSA-5173214 O-glycosylation of TSR domain-containing proteins 36/7348 38/10654 1.1619346459684132e-4 4.138477555162056e-4 1.7807191445571866e-4 11173/10418/339366/5199/81794/11096/54507/54437/9509/170691/56999/92949/9510/81792/221981/57188/10417/9719/79875/7058/9507/170690/11093/171019/11095/23275/140766/9508/9037/80070/55901/11174/170692/170689/7057/157869 36 Human_SARS_coronavirus_2 R-HSA-5655302 Signaling by FGFR1 in disease 36/7348 38/10654 1.1619346459684132e-4 4.138477555162056e-4 1.7807191445571866e-4 5295/4893/11052/2250/5335/9530/613/6776/11064/2885/9846/2253/3845/3265/7750/8805/26127/5290/8074/2260/2249/399687/2247/2246/2251/1523/9208/6774/6772/6654/11160/2549/8822/2254/26281/10818 36 Human_SARS_coronavirus_2 R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 24/7348 24/10654 1.3264286015031746e-4 4.6889251063137225e-4 2.017567714917987e-4 2237/1763/5982/5422/6117/10714/5558/6118/3978/5557/5985/5984/23649/5424/54107/5425/5111/6119/5427/5983/56655/57804/5426/5981 24 Human_SARS_coronavirus_2 R-HSA-450302 activated TAK1 mediates p38 MAPK activation 24/7348 24/10654 1.3264286015031746e-4 4.6889251063137225e-4 2.017567714917987e-4 1432/3654/7334/7314/257397/5606/8767/23118/8517/9261/10454/6233/5600/5608/387522/7867/64127/3656/7189/7311/6885/10392/7316/7335 24 Human_SARS_coronavirus_2 R-HSA-5627123 RHO GTPases activate PAKs 24/7348 24/10654 1.3264286015031746e-4 4.6889251063137225e-4 2.017567714917987e-4 2017/79784/4628/5062/5879/4638/4659/4771/801/5500/805/2316/10627/5063/998/5058/4660/4629/3984/4627/10398/4637/103910/808 24 Human_SARS_coronavirus_2 R-HSA-449147 Signaling by Interleukins 353/7348 461/10654 1.374082768945065e-4 4.8452694146840946e-4 2.0848401114325965e-4 5295/729230/8454/6804/3605/7124/2308/834/5689/3725/7291/5777/9252/1437/4790/5682/5291/1511/26469/5657/5783/27178/1848/356/3593/246/9021/8878/6624/5908/3082/5743/3091/941/1265/143471/3383/5705/6657/3576/3313/3662/6776/3688/11141/4985/5709/6175/9978/2920/5695/84868/1435/4792/3936/59307/7133/177/4609/5898/5711/4988/1432/3558/3717/4088/836/5683/200081/2534/84867/2162/5699/3181/5702/4001/3654/3563/2885/8660/6196/3594/1154/9846/6347/5518/1386/55540/6382/7040/6197/4282/7334/3312/1399/3551/3965/3569/5062/5696/5691/51231/4692/7314/3572/3596/5515/257397/3598/5718/54014/8945/1326/5601/1072/3635/3592/5290/3667/6627/5606/7412/5700/122706/5707/8767/3911/1849/29110/1439/5594/4582/23198/23118/6367/9987/64806/8517/6778/7534/6810/332/5528/4313/3565/3934/3185/5970/5443/84818/9261/3718/3627/8809/9861/5519/5598/4208/3567/598/2247/5698/5692/5713/2335/595/6195/5710/10454/7157/5478/5719/27189/6233/7525/4128/6844/7409/2353/604/6809/3932/7076/302/552900/51561/8835/5600/6773/7850/7297/5781/5608/4791/9655/3562/351/6464/3566/6597/5782/387522/6351/7184/6775/3684/9446/54472/821/4318/5706/3726/58480/301/4478/1438/53833/3581/6616/79155/6774/920/6850/5780/5714/6772/8651/7867/5566/64127/8503/1901/2889/5688/79923/5687/4067/5708/5602/3656/57162/5771/998/9244/6648/7189/112744/6654/5704/3716/7311/2939/5293/2185/240/6655/6356/5694/23765/6416/1234/3586/829/28511/5595/5516/1147/5778/1845/596/5055/5684/5720/6885/2309/5604/4215/3561/10392/207/5292/5451/7422/5690/3553/2625/1230/5717/2919/9491/6500/3568/25930/10197/4615/3597/2357/1436/7316/10213/3560/6352/7335/4205/3055/1026/6348/4793/5775/3146/6647/6364/5715/7132/5701/867/466/6950/23291/5685/132014/3320/5686/4843/5306/9466/6288/6285/5609/1398/948/5716/1385/6363/3575/4507/6845/5296/6935/3687/5599/5784/7431/375/3559/3162/1278/4170/5693/3689/5721/5724/5034 353 Human_SARS_coronavirus_2 R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 49/7348 54/10654 1.388605736645991e-4 4.884299780142864e-4 2.1016342387572215e-4 5431/5435/9978/5433/10980/2965/5439/10987/2967/7314/404672/3150/5438/10920/2068/6233/7874/8451/10450/5434/5436/8450/4331/2966/1161/1642/2071/2873/7311/8533/5432/51138/9318/6917/5440/902/27339/5430/5441/7316/64708/5437/2033/2968/56949/9716/57461/1022/50813 49 Human_SARS_coronavirus_2 R-HSA-176187 Activation of ATR in response to replication stress 35/7348 37/10654 1.6033983045098772e-4 5.584249267430952e-4 2.4028110448709076e-4 5982/4174/84515/4998/10926/990/55388/6117/5001/6118/23594/63967/993/5985/4175/5984/5884/5810/4999/4172/5000/8318/4173/6119/3364/1111/23595/5983/4176/1017/5883/8317/545/4171/995 35 Human_SARS_coronavirus_2 R-HSA-5083635 Defective B3GALTL causes Peters-plus syndrome (PpS) 35/7348 37/10654 1.6033983045098772e-4 5.584249267430952e-4 2.4028110448709076e-4 11173/10418/339366/5199/81794/11096/54507/54437/9509/170691/56999/92949/9510/81792/221981/57188/10417/9719/79875/7058/9507/170690/11093/171019/11095/140766/9508/9037/80070/55901/11174/170692/170689/7057/157869 35 Human_SARS_coronavirus_2 R-HSA-6806003 Regulation of TP53 Expression and Degradation 35/7348 37/10654 1.6033983045098772e-4 5.584249267430952e-4 2.4028110448709076e-4 11200/472/639/4194/8900/2475/5518/51230/7314/5515/117584/890/983/5519/10000/900/7157/6233/7874/253260/5170/1029/80196/64223/1616/208/79109/7311/5516/1017/207/7316/9099/5527/4193 35 Human_SARS_coronavirus_2 R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 35/7348 37/10654 1.6033983045098772e-4 5.584249267430952e-4 2.4028110448709076e-4 79718/27327/346/9612/64240/55818/6907/192669/4343/1071/9619/10062/344/5360/64241/348/6257/26523/341/19/9682/10123/27161/8841/347/57690/192670/9611/2874/2033/221656/23028/6256/23112/8648 35 Human_SARS_coronavirus_2 R-HSA-418597 G alpha (z) signalling events 44/7348 48/10654 1.719759665019663e-4 5.960147466514224e-4 2.564553886432831e-4 2788/5579/2770/5578/5582/5583/107/2782/6004/2773/2787/10681/112/111/2792/5588/2785/2783/2784/2771/5580/196883/115/2791/2781/150/113/8601/2786/109/151/54331/59345/51764/94235/114/108/55970/2778/346562/152/2793/5581/2790 44 Human_SARS_coronavirus_2 R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 44/7348 48/10654 1.719759665019663e-4 5.960147466514224e-4 2.564553886432831e-4 5295/5777/1437/5291/6776/3558/3717/2534/3563/2885/9846/1399/7314/3635/5290/1439/7534/3718/3567/6233/7525/7409/5781/3562/6464/1438/6850/5566/8503/2889/4067/6654/3716/7311/5293/3561/3568/7316/3560/3055/867/1398/5296/3559 44 Human_SARS_coronavirus_2 R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 52/7348 58/10654 1.8729996974057973e-4 6.41264303179612e-4 2.7592553207609304e-4 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/9794/57534/28514/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/102/5664/8850/3066/6233/5663/142678/10046/1024/10014/9148/7311/51107/4851/8841/23462/6500/7316/9611/54492/2033/55294/3065/54567/3516 52 Human_SARS_coronavirus_2 R-HSA-2644603 Signaling by NOTCH1 in Cancer 52/7348 58/10654 1.8729996974057973e-4 6.41264303179612e-4 2.7592553207609304e-4 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/9794/57534/28514/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/102/5664/8850/3066/6233/5663/142678/10046/1024/10014/9148/7311/51107/4851/8841/23462/6500/7316/9611/54492/2033/55294/3065/54567/3516 52 Human_SARS_coronavirus_2 R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 52/7348 58/10654 1.8729996974057973e-4 6.41264303179612e-4 2.7592553207609304e-4 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/9794/57534/28514/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/102/5664/8850/3066/6233/5663/142678/10046/1024/10014/9148/7311/51107/4851/8841/23462/6500/7316/9611/54492/2033/55294/3065/54567/3516 52 Human_SARS_coronavirus_2 R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 52/7348 58/10654 1.8729996974057973e-4 6.41264303179612e-4 2.7592553207609304e-4 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/9794/57534/28514/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/102/5664/8850/3066/6233/5663/142678/10046/1024/10014/9148/7311/51107/4851/8841/23462/6500/7316/9611/54492/2033/55294/3065/54567/3516 52 Human_SARS_coronavirus_2 R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 52/7348 58/10654 1.8729996974057973e-4 6.41264303179612e-4 2.7592553207609304e-4 8454/79718/892/182/23385/9978/9759/9612/4609/22938/1387/6907/9794/57534/28514/7314/79885/2648/9734/55869/51564/55534/3280/84441/10013/83933/3714/102/5664/8850/3066/6233/5663/142678/10046/1024/10014/9148/7311/51107/4851/8841/23462/6500/7316/9611/54492/2033/55294/3065/54567/3516 52 Human_SARS_coronavirus_2 R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 23/7348 23/10654 1.9250870256082287e-4 6.465731720213861e-4 2.78209851431818e-4 5431/5435/5433/5439/51497/5438/7936/6829/25920/2963/5434/5436/2962/5432/22916/5440/5430/5441/7469/4686/9150/5437/6827 23 Human_SARS_coronavirus_2 R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 23/7348 23/10654 1.9250870256082287e-4 6.465731720213861e-4 2.78209851431818e-4 11065/7321/8697/51529/29945/51434/29882/7314/996/983/51433/119504/7324/64682/6233/246184/8881/891/10393/7311/25906/991/7316 23 Human_SARS_coronavirus_2 R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 23/7348 23/10654 1.9250870256082287e-4 6.465731720213861e-4 2.78209851431818e-4 7321/8239/9612/4089/23327/4088/7314/6497/51592/7323/7050/5494/6233/60436/142/4087/7311/64750/54778/7316/9611/3065/6498 23 Human_SARS_coronavirus_2 R-HSA-428930 Thromboxane signalling through TP receptor 23/7348 23/10654 1.9250870256082287e-4 6.465731720213861e-4 2.78209851431818e-4 2788/2769/2782/2776/2787/10681/2792/2785/2783/2784/2791/6915/2786/54331/59345/51764/94235/55970/2767/2793/9630/2790/10672 23 Human_SARS_coronavirus_2 R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 23/7348 23/10654 1.9250870256082287e-4 6.465731720213861e-4 2.78209851431818e-4 3654/7334/7314/257397/5601/8767/23118/8517/10454/6233/387522/64127/5602/3656/7189/7311/6416/6885/10392/7316/7335/5609/5599 23 Human_SARS_coronavirus_2 R-HSA-5654693 FRS-mediated FGFR1 signaling 23/7348 23/10654 1.9250870256082287e-4 6.465731720213861e-4 2.78209851431818e-4 4893/2250/2885/2253/3845/3265/8074/2260/2249/2248/2247/2246/2251/5781/9365/6654/8822/10817/2254/26281/10818/2255/27006 23 Human_SARS_coronavirus_2 R-HSA-5654695 PI-3K cascade:FGFR2 23/7348 23/10654 1.9250870256082287e-4 6.465731720213861e-4 2.78209851431818e-4 5295/2250/2885/2252/2253/5290/8823/8074/2249/2248/2247/2246/2251/5781/2263/2549/8822/8817/2254/26281/10818/2255/27006 23 Human_SARS_coronavirus_2 R-HSA-5654699 SHC-mediated cascade:FGFR2 23/7348 23/10654 1.9250870256082287e-4 6.465731720213861e-4 2.78209851431818e-4 4893/2250/2885/2252/2253/3845/3265/8823/8074/2249/2248/2247/2246/2251/6464/2263/6654/8822/8817/2254/26281/2255/27006 23 Human_SARS_coronavirus_2 R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 67/7348 77/10654 1.956355833948798e-4 6.55518281801801e-4 2.820587857376915e-4 1912/23165/7486/6045/80012/10274/348995/6613/57122/23511/1911/6672/23279/23225/165918/57332/5371/8924/672/9972/6612/8021/6117/55746/51564/51588/7518/100532731/10762/79902/9656/9883/84733/9063/6396/129401/7703/6015/8554/4928/5903/55706/7175/1029/8535/5885/641/493861/4927/8243/142/1069/8086/7329/648/81929/9631/79023/23636/10735/53371/23137/9688/7341/9126/8480/7508 67 Human_SARS_coronavirus_2 R-HSA-180786 Extension of Telomeres 29/7348 30/10654 2.0634376086282676e-4 6.833022900703444e-4 2.9401378966772805e-4 2237/1763/5982/5422/6117/10714/5558/6118/3978/5557/5985/5984/23649/8607/5424/55651/54107/5425/5111/6119/5427/5983/56655/7015/57804/10856/5426/1736/5981 29 Human_SARS_coronavirus_2 R-HSA-3000157 Laminin interactions 29/7348 30/10654 2.0634376086282676e-4 6.833022900703444e-4 2.9401378966772805e-4 3675/3688/3910/3908/3679/1285/3655/1294/3918/3911/1284/284217/3672/3909/1288/3685/3691/1286/1287/4811/3912/3913/1282/3339/3915/3673/3914/80781/10319 29 Human_SARS_coronavirus_2 R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 29/7348 30/10654 2.0634376086282676e-4 6.833022900703444e-4 2.9401378966772805e-4 7124/7375/10616/1540/3551/7314/257397/81858/8737/55072/23118/8517/7128/10454/6233/331/8717/330/27005/7311/1147/7186/56957/6885/7316/7132/329/9099/7185 29 Human_SARS_coronavirus_2 R-HSA-6804758 Regulation of TP53 Activity through Acetylation 29/7348 30/10654 2.0634376086282676e-4 6.833022900703444e-4 2.9401378966772805e-4 64769/84289/29117/5928/1107/5371/8396/23774/3622/79837/27154/57459/10000/7994/3066/7157/5608/7862/9219/5931/1108/54815/208/53615/5305/207/2033/3065/5300 29 Human_SARS_coronavirus_2 R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 29/7348 30/10654 2.0634376086282676e-4 6.833022900703444e-4 2.9401378966772805e-4 11065/7321/65264/8239/55236/3093/7347/7328/7332/7314/10477/92912/29089/7324/6233/7874/7326/7317/8078/7327/7311/997/7319/7320/7316/54926/7322/55284/27338 29 Human_SARS_coronavirus_2 R-HSA-1222556 ROS and RNS production in phagocytes 34/7348 36/10654 2.209587427907858e-4 7.249087292486569e-4 3.119163593432023e-4 535/50617/10312/534/51606/526/155066/9550/9114/525/6556/529/5880/533/1535/523/528/4842/4688/653361/527/84329/127124/4353/23545/90423/245972/8992/4843/4846/245973/1536/51382/9296 34 Human_SARS_coronavirus_2 R-HSA-176033 Interactions of Vpr with host cellular proteins 34/7348 36/10654 2.209587427907858e-4 7.249087292486569e-4 3.119163593432023e-4 23165/348995/57122/23511/292/23279/23225/3836/9972/8021/55746/10762/79902/11168/9883/6396/129401/4928/5903/55706/7175/293/4927/8086/81929/9631/3159/79023/23636/53371/9688/8815/8480/291 34 Human_SARS_coronavirus_2 R-HSA-177243 Interactions of Rev with host cellular proteins 34/7348 36/10654 2.209587427907858e-4 7.249087292486569e-4 3.119163593432023e-4 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/5902/7514/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/1104/5905/3837/81929/9631/79023/23636/53371/9688/8480 34 Human_SARS_coronavirus_2 R-HSA-6804757 Regulation of TP53 Degradation 34/7348 36/10654 2.209587427907858e-4 7.249087292486569e-4 3.119163593432023e-4 11200/472/4194/8900/2475/5518/51230/7314/5515/117584/890/983/5519/10000/900/7157/6233/7874/253260/5170/1029/80196/64223/1616/208/79109/7311/5516/1017/207/7316/9099/5527/4193 34 Human_SARS_coronavirus_2 R-HSA-73762 RNA Polymerase I Transcription Initiation 43/7348 47/10654 2.3001892992851125e-4 7.511472677111198e-4 3.2320637291522917e-4 9112/5435/5928/2965/64425/1107/2967/2648/30834/404672/8850/57459/2068/3066/9533/5434/9015/79101/9219/5931/221830/7270/4331/9013/1108/2966/54815/2071/57504/6908/53615/5440/902/9014/25885/5441/7343/5437/3065/2968/84172/1022/10919 43 Human_SARS_coronavirus_2 R-HSA-9024446 NR1H2 and NR1H3-mediated signaling 43/7348 47/10654 2.3001892992851125e-4 7.511472677111198e-4 3.2320637291522917e-4 79718/27327/346/9612/64240/55818/6907/192669/4343/1071/9619/10062/344/5360/64241/54659/348/6257/26523/29116/5105/6319/341/19/5346/9682/10123/27161/8841/347/8204/57690/6720/192670/9611/2874/2194/2033/221656/23028/6256/23112/8648 43 Human_SARS_coronavirus_2 R-HSA-382556 ABC-family proteins mediated transport 87/7348 103/10654 2.347586998234727e-4 7.648589897474434e-4 3.291063024447423e-4 5689/1965/5682/20/23/143471/91319/5705/8504/5709/5695/64240/5711/5683/5699/6400/3767/5702/51009/4363/225/10057/5696/5691/9619/7314/5718/5700/122706/5707/10956/79139/91445/64241/23198/9861/11194/8894/5698/215/5692/5713/5710/5719/10613/6233/27248/10058/1968/6048/5706/10257/335/5714/22/5688/5687/10347/23456/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/89845/10197/5824/1244/7316/10213/7415/5715/5701/5825/5685/5686/5716/21/368/5693/5721 87 Human_SARS_coronavirus_2 R-HSA-70171 Glycolysis 62/7348 71/10654 2.718714509657799e-4 8.837384635991097e-4 3.8025819397028625e-4 23165/7167/5211/348995/57122/3099/23511/23279/23225/9972/5518/8021/2026/55746/2027/5515/2597/5567/10762/5528/283871/2646/79902/5519/9883/226/2821/5208/2645/6396/129401/230/4928/5903/55706/7175/5568/3101/4927/5566/2023/8086/5207/5516/81929/9631/5315/79023/23636/5214/83440/53371/5230/3098/9688/5210/5209/5224/5213/10007/8480/5223 62 Human_SARS_coronavirus_2 R-HSA-1250196 SHC1 events in ERBB2 signaling 22/7348 22/10654 2.793819991300393e-4 8.978321517497174e-4 3.863224772659396e-4 4893/5578/2064/145957/9542/2885/3845/3265/1839/2065/2069/5580/6464/5782/3084/6654/10718/1956/685/1950/2066/5581 22 Human_SARS_coronavirus_2 R-HSA-392170 ADP signalling through P2Y purinoceptor 12 22/7348 22/10654 2.793819991300393e-4 8.978321517497174e-4 3.863224772659396e-4 2788/64805/2770/2782/2773/2787/10681/2792/2785/2783/2784/2771/2791/2786/54331/59345/51764/94235/55970/346562/2793/2790 22 Human_SARS_coronavirus_2 R-HSA-5654712 FRS-mediated FGFR4 signaling 22/7348 22/10654 2.793819991300393e-4 8.978321517497174e-4 3.863224772659396e-4 4893/9965/2264/2885/2253/3845/3265/8823/8074/2249/2247/2246/2251/5781/6654/8822/8817/10817/2254/152831/26281/10818 22 Human_SARS_coronavirus_2 R-HSA-5655332 Signaling by FGFR3 in disease 22/7348 22/10654 2.793819991300393e-4 8.978321517497174e-4 3.863224772659396e-4 5295/4893/2250/5335/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/6654/2549/8822/8817/2254/26281/10818/2261 22 Human_SARS_coronavirus_2 R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 22/7348 22/10654 2.793819991300393e-4 8.978321517497174e-4 3.863224772659396e-4 5295/4893/2250/5335/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/6654/2549/8822/8817/2254/26281/10818/2261 22 Human_SARS_coronavirus_2 R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 86/7348 102/10654 2.900873752677732e-4 9.242395647887315e-4 3.97685154803757e-4 8454/8792/7124/5689/5682/356/9039/143471/5705/10673/5709/5695/7133/5711/5683/5699/5702/8740/944/7187/51330/958/5696/5691/939/7314/5718/8945/8744/5700/122706/5707/23198/9020/8741/1896/9861/5698/5692/5713/5710/8718/9040/5719/6233/8742/4791/959/4055/8600/330/5706/5714/5688/5687/5708/5704/7311/5971/115650/5694/1147/4050/5684/5720/7186/5690/5717/9491/6500/10197/7316/10213/970/5715/7132/5701/329/23291/5685/5686/4049/5716/943/5693/5721 86 Human_SARS_coronavirus_2 R-HSA-162588 Budding and maturation of HIV virion 28/7348 29/10654 2.902138378827417e-4 9.242395647887315e-4 3.97685154803757e-4 51652/27243/55048/51271/23327/29082/27183/92421/7314/137492/25978/51160/10015/91782/79720/51534/89853/51510/5478/6233/79643/128866/7311/93343/7251/155382/7316/9525 28 Human_SARS_coronavirus_2 R-HSA-186763 Downstream signal transduction 28/7348 29/10654 2.902138378827417e-4 9.242395647887315e-4 3.97685154803757e-4 5295/4893/5335/5291/6776/2885/8440/9564/3845/3265/1399/5290/5921/6778/6714/5154/5781/6774/6772/2889/5159/2886/6654/4690/1398/5155/5296/5156 28 Human_SARS_coronavirus_2 R-HSA-5218920 VEGFR2 mediated vascular permeability 28/7348 29/10654 2.902138378827417e-4 9.242395647887315e-4 3.97685154803757e-4 857/2475/5062/5879/57761/1500/10000/3728/7410/7409/117145/801/253260/805/5170/10451/64223/1003/5063/208/79109/5058/1495/1499/207/3320/4846/808 28 Human_SARS_coronavirus_2 R-HSA-6782135 Dual incision in TC-NER 58/7348 66/10654 2.929366437724807e-4 9.308144141444667e-4 4.005142048503699e-4 5982/5431/5435/9978/5433/2965/5439/2967/6117/10714/7314/6118/404672/3150/5438/5985/2068/5984/6233/7874/5424/8451/10450/5434/5436/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/2071/51426/7311/5983/5432/56655/6917/5440/902/27339/5430/57804/5441/7316/5426/5437/2033/2968/56949/9716/5981/57461/1022 58 Human_SARS_coronavirus_2 R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 33/7348 35/10654 3.040610241822013e-4 9.618395709029812e-4 4.138638219176083e-4 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/7884/4927/10482/8086/22916/81929/9631/79023/23636/4686/53371/9688/10189/8480 33 Human_SARS_coronavirus_2 R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 33/7348 35/10654 3.040610241822013e-4 9.618395709029812e-4 4.138638219176083e-4 23165/91754/348995/57122/23511/23279/23225/9972/8021/55746/10762/983/79902/9883/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/81929/9631/140609/10783/79023/23636/53371/9688/8480 33 Human_SARS_coronavirus_2 R-HSA-112382 Formation of RNA Pol II elongation complex 54/7348 61/10654 3.1004672914818174e-4 9.76405512284029e-4 4.201313080474717e-4 5431/5435/5433/2965/5439/2967/11198/904/51497/4300/80349/404672/5438/2068/1025/23168/55677/7936/6829/123169/25920/85403/2963/5434/5436/9646/79577/4331/2966/2962/4298/8812/905/2071/27125/5432/22916/55840/6917/5440/902/6830/5430/6749/5441/7469/4686/9150/54623/5437/6827/2968/1022/8178 54 Human_SARS_coronavirus_2 R-HSA-75955 RNA Polymerase II Transcription Elongation 54/7348 61/10654 3.1004672914818174e-4 9.76405512284029e-4 4.201313080474717e-4 5431/5435/5433/2965/5439/2967/11198/904/51497/4300/80349/404672/5438/2068/1025/23168/55677/7936/6829/123169/25920/85403/2963/5434/5436/9646/79577/4331/2966/2962/4298/8812/905/2071/27125/5432/22916/55840/6917/5440/902/6830/5430/6749/5441/7469/4686/9150/54623/5437/6827/2968/1022/8178 54 Human_SARS_coronavirus_2 R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 72/7348 84/10654 3.1944674462142694e-4 0.0010037726597659949 4.3190694360511063e-4 10445/5982/6613/9978/10980/2965/10987/2967/6612/6117/7334/10714/7314/6118/83444/404672/86/3978/1643/29844/5985/10920/2068/5984/6233/8607/5424/5886/8451/8554/7515/54107/8450/4331/5425/5111/2966/6119/5427/1642/142/2071/1069/7329/51426/2873/7311/3980/60/8533/5983/51138/7528/56655/9318/902/57804/7336/54778/7316/64708/5426/7341/4798/79913/10401/2968/5887/5981/1022/50813/7508 72 Human_SARS_coronavirus_2 R-HSA-400253 Circadian Clock 61/7348 70/10654 3.47073396438906e-4 0.0010881635977042419 4.682189827090388e-4 8454/79718/5936/3091/5469/1387/150094/6907/2155/5499/10499/23054/1386/9575/23411/9572/85441/7314/96764/5054/8945/10135/1454/5465/64784/4208/6604/80205/6233/8864/1453/5500/5187/26224/1374/1407/406/4209/5501/8553/2908/1390/7311/23373/8841/8204/4862/6500/200186/1408/6720/7316/9611/2033/79365/6256/10498/1385/8648/551/10891 61 Human_SARS_coronavirus_2 R-HSA-5675221 Negative regulation of MAPK pathway 37/7348 40/10654 3.7154830045365943e-4 0.0011623214531891026 5.001278939501984e-4 4893/1844/1850/1848/5526/1852/5605/5037/5894/5518/4140/3845/3265/7314/5515/8844/1849/5594/5528/5519/80824/6233/1843/369/11221/673/8315/5529/7311/5536/7529/5595/5516/5604/5525/7316/5527 37 Human_SARS_coronavirus_2 R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission 164/7348 206/10654 3.750818223445291e-4 0.0011707852026383314 5.037697067854951e-4 2788/5563/4893/3760/5579/5331/23426/2770/51807/817/2550/5578/347688/5582/10381/7278/1137/9463/107/9568/3762/2774/7846/55584/9495/2782/81027/1134/1741/163/6196/3765/3773/8874/6197/8825/3845/3265/1136/2773/5879/2787/5923/818/57554/161/79861/5567/4646/170572/5594/51422/10681/112/2892/5573/2902/111/116444/2792/3359/6714/2742/2566/8001/2785/10376/6195/2783/2784/83988/5613/2906/2771/196883/3759/115/1175/801/2891/2791/2554/4747/805/5170/1173/84617/3838/8573/2904/2890/10382/2556/5568/2036/7277/160/113/116443/80852/10645/2899/23229/55327/5566/2905/5571/27330/23236/347733/3084/816/3763/2786/5577/3772/10369/2893/5562/10383/84790/5564/5565/5924/7280/109/5595/64130/2743/815/54331/28964/27020/3761/5575/59345/3766/2562/51764/94235/114/5330/108/112714/55970/346562/2793/5576/2903/4137/2066/4905/1143/27092/9647/1742/88/1385/3768/808/1144/8536/4193/2790 164 Human_SARS_coronavirus_2 R-HSA-111931 PKA-mediated phosphorylation of CREB 21/7348 21/10654 4.0544135345294214e-4 0.0012408962635983985 5.339373485892016e-4 107/5567/112/5573/111/5613/196883/115/801/805/5568/113/5566/5577/109/5575/114/108/5576/1385/808 21 Human_SARS_coronavirus_2 R-HSA-416572 Sema4D induced cell migration and growth-cone collapse 21/7348 21/10654 4.0544135345294214e-4 0.0012408962635983985 5.339373485892016e-4 388/2064/23365/79784/9475/4628/6093/10507/27289/389/5364/10627/387/4629/3984/4627/3985/10398/9826/4637/103910 21 Human_SARS_coronavirus_2 R-HSA-445144 Signal transduction by L1 21/7348 21/10654 4.0544135345294214e-4 0.0012408962635983985 5.339373485892016e-4 1459/1460/8829/4684/3688/1457/5605/3690/5879/5594/2260/7410/3685/3674/3678/3897/1956/5058/5595/5604/3680 21 Human_SARS_coronavirus_2 R-HSA-500657 Presynaptic function of Kainate receptors 21/7348 21/10654 4.0544135345294214e-4 0.0012408962635983985 5.339373485892016e-4 2788/5331/2782/2787/10681/2792/2785/2783/2784/2791/2899/23236/2786/54331/59345/51764/94235/5330/55970/2793/2790 21 Human_SARS_coronavirus_2 R-HSA-5218921 VEGFR2 mediated cell proliferation 21/7348 21/10654 4.0544135345294214e-4 0.0012408962635983985 5.339373485892016e-4 4893/5335/5579/5578/3709/3845/3265/8877/5921/6714/5580/3791/3710/801/805/5170/5590/7422/3708/10768/808 21 Human_SARS_coronavirus_2 R-HSA-5620916 VxPx cargo-targeting to cilium 21/7348 21/10654 4.0544135345294214e-4 0.0012408962635983985 5.339373485892016e-4 55763/1260/1258/1262/60412/6010/9727/5310/8729/11336/117177/378/4218/50807/5311/55770/23265/10640/8766/149371/54536 21 Human_SARS_coronavirus_2 R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 21/7348 21/10654 4.0544135345294214e-4 0.0012408962635983985 5.339373485892016e-4 2237/5982/6117/10714/6118/328/3978/5985/5984/5424/54107/5423/5425/5111/6119/5427/5983/56655/57804/5426/5981 21 Human_SARS_coronavirus_2 R-HSA-5654688 SHC-mediated cascade:FGFR1 21/7348 21/10654 4.0544135345294214e-4 0.0012408962635983985 5.339373485892016e-4 4893/2250/2885/2253/3845/3265/8074/2260/2249/2248/2247/2246/2251/6464/9365/6654/8822/2254/26281/2255/27006 21 Human_SARS_coronavirus_2 R-HSA-5654689 PI-3K cascade:FGFR1 21/7348 21/10654 4.0544135345294214e-4 0.0012408962635983985 5.339373485892016e-4 5295/2250/2885/2253/5290/8074/2260/2249/2248/2247/2246/2251/5781/9365/2549/8822/2254/26281/10818/2255/27006 21 Human_SARS_coronavirus_2 R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 146/7348 182/10654 4.0735934234175806e-4 0.0012425451216451066 5.346468252146741e-4 1912/23165/7068/7486/9112/6045/9212/80012/10274/348995/6613/57122/7181/23511/28996/4792/3190/9759/9612/8856/1911/6790/6672/23279/1387/1789/23225/23512/165918/57332/7067/7428/1107/5371/8924/4152/672/115426/9972/10499/6612/5914/8021/6117/11315/55746/4286/10062/7150/6670/83746/3622/1788/51564/51588/7518/3619/7153/51602/2516/100532731/8517/332/10762/5465/1655/5970/2099/79902/2494/9656/9883/84733/3066/7157/668/7158/10155/9063/7155/7690/6396/129401/7703/4791/6015/8554/7020/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/493861/5111/4927/10521/1616/2908/8243/142/9971/1069/8086/7329/367/25942/9641/648/23468/5905/81929/1487/55143/9631/5468/8204/3090/79023/23636/10735/3183/53371/23137/9688/7341/10401/2033/9126/3065/6256/5987/6294/8648/6304/8480/10891/7508/4193 146 Human_SARS_coronavirus_2 R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 27/7348 28/10654 4.0773757881423583e-4 0.0012425451216451066 5.346468252146741e-4 10381/7278/10576/7846/7411/81027/10574/10693/5201/5204/10575/10471/5202/84617/10382/7277/347733/10383/60/84790/22948/7280/10694/5203/7203/908/6950 27 Human_SARS_coronavirus_2 R-HSA-3899300 SUMOylation of transcription cofactors 41/7348 45/10654 4.093076282914247e-4 0.0012446472825894078 5.355513506563521e-4 1912/6045/80012/6613/28996/9612/1911/1387/57332/4152/115426/10499/6612/11315/3622/51588/100532731/1655/84733/10155/9063/7690/7703/6015/8554/8535/4869/10210/10521/1616/7329/25942/648/1487/8204/7341/10401/2033/6294/8648/10891 41 Human_SARS_coronavirus_2 R-HSA-1428517 The citric acid (TCA) cycle and respiratory electron transport 140/7348 174/10654 4.1428166739790274e-4 0.001252554414121419 5.389536599137797e-4 5161/4723/2110/5160/5165/4719/9997/4724/8050/6389/50/4715/4538/6341/3939/160287/4514/4695/4540/4696/4509/3948/4705/3029/7384/137682/4513/4191/3421/4720/79133/51079/9377/1329/54704/4702/5166/7388/55863/1737/4519/1351/4536/6390/4725/10975/5467/4541/10131/23539/5162/4508/4731/4707/1431/55967/55066/8801/2271/1337/4716/126328/9167/5164/93058/4512/4967/6391/6392/4700/4711/4712/3418/2954/1743/1345/55471/728294/4710/51295/7386/7416/4714/84987/4701/10128/27089/2108/7381/4726/4708/81889/1340/4713/4697/92483/4709/91942/51300/3419/3945/4722/4717/9123/29796/4535/29078/4704/2109/8802/3420/51103/4729/4718/54205/57546/7385/8803/80219/4728/374291/5163/1350/23530/682/25915/6256/1349/4706/1738/28976/6834/54539/4698/1327/4537/1537/4694/6566/80224 140 Human_SARS_coronavirus_2 R-HSA-159227 Transport of the SLBP independent Mature mRNA 32/7348 34/10654 4.177893814467045e-4 0.001252554414121419 5.389536599137797e-4 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10482/8086/22916/81929/9631/79023/23636/4686/53371/9688/10189/8480 32 Human_SARS_coronavirus_2 R-HSA-165054 Rev-mediated nuclear export of HIV RNA 32/7348 34/10654 4.177893814467045e-4 0.001252554414121419 5.389536599137797e-4 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/5902/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/1104/5905/81929/9631/79023/23636/53371/9688/8480 32 Human_SARS_coronavirus_2 R-HSA-187687 Signalling to ERKs 32/7348 34/10654 4.177893814467045e-4 0.001252554414121419 5.389536599137797e-4 4893/5605/5898/1432/5603/2885/3845/3265/1399/5899/5594/9261/6714/4914/5600/6300/6464/673/7867/2889/6654/5900/7529/5595/25759/5604/57498/10818/53358/4803/1398/5906 32 Human_SARS_coronavirus_2 R-HSA-4085377 SUMOylation of SUMOylation proteins 32/7348 34/10654 4.177893814467045e-4 0.001252554414121419 5.389536599137797e-4 23165/348995/6613/57122/23511/23279/23225/9972/8021/55746/51588/10762/79902/9883/6396/129401/4928/5903/55706/7175/10210/4927/8086/7329/81929/9631/79023/23636/53371/9688/7341/8480 32 Human_SARS_coronavirus_2 R-HSA-112040 G-protein mediated events 49/7348 55/10654 4.181086870334581e-4 0.001252554414121419 5.389536599137797e-4 2780/5331/2770/817/5578/5582/2775/107/3709/2774/2773/818/5567/5594/112/5573/111/5613/2771/5332/5580/3710/196883/115/801/805/3838/2781/5568/113/10645/5566/23236/816/5577/109/815/5321/5575/114/3708/5330/108/2779/10768/346562/5576/1385/808 49 Human_SARS_coronavirus_2 R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF) 49/7348 55/10654 4.181086870334581e-4 0.001252554414121419 5.389536599137797e-4 79718/51141/10484/3638/5469/6713/1387/6907/9632/6309/10499/23054/85441/7108/31/96764/4598/8720/5465/2222/6667/3156/6604/80205/51128/10654/6319/6721/10802/4800/57678/32/1595/5901/4047/9871/3837/4802/79071/6720/2194/22937/1717/6256/10498/51360/2224/8648/10427 49 Human_SARS_coronavirus_2 R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 45/7348 50/10654 4.227266780222475e-4 0.0012637114645316237 5.437543560628888e-4 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/5706/50489/5714/5688/5687/5708/5704/5694/5684/5720/5690/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 45 Human_SARS_coronavirus_2 R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 36/7348 39/10654 5.013985070695885e-4 0.0014957330991485192 6.435894672134625e-4 5982/25898/6117/10714/55666/7314/6118/9636/11201/5985/5984/6233/5424/124739/54107/7706/5425/5111/6119/83932/5427/5429/9246/51426/7311/7318/5983/56655/57804/7316/5426/9100/10459/7415/5981/5980 36 Human_SARS_coronavirus_2 R-HSA-112043 PLC beta mediated events 48/7348 54/10654 5.443441355426674e-4 0.0016204265424364876 6.972430146119929e-4 2780/5331/2770/817/5578/5582/2775/107/3709/2773/818/5567/5594/112/5573/111/5613/2771/5332/5580/3710/196883/115/801/805/3838/2781/5568/113/10645/5566/23236/816/5577/109/815/5321/5575/114/3708/5330/108/2779/10768/346562/5576/1385/808 48 Human_SARS_coronavirus_2 R-HSA-2990846 SUMOylation 150/7348 188/10654 5.458242919914904e-4 0.0016214192203276628 6.976701476582961e-4 1912/10054/23165/7068/7486/9112/6045/9212/80012/10274/348995/6613/57122/7181/23511/28996/4792/3190/9759/9612/8856/1911/6790/6672/23279/1387/1789/23225/10055/23512/165918/57332/7067/7428/1107/5371/8924/4152/672/115426/9972/10499/6612/5914/8021/6117/11315/55746/4286/10062/7150/6670/83746/3622/1788/51564/51588/7518/3619/7153/51602/2516/100532731/8517/332/10762/5465/1655/5970/2099/79902/2494/9656/9883/84733/3066/7157/668/7158/10155/9063/7155/7690/6396/129401/7703/4791/6015/8554/7020/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/493861/5111/4927/10521/1616/2908/8243/142/9971/1069/8086/7329/367/25942/9641/648/23468/5905/81929/29843/1487/55143/9631/5468/8204/3090/79023/23636/10735/3183/53371/23137/9688/7341/10401/59343/2033/9126/3065/6256/5987/6294/8648/6304/8480/10891/7508/4193 150 Human_SARS_coronavirus_2 R-HSA-177929 Signaling by EGFR 44/7348 49/10654 5.557622138314746e-4 0.0016474796024270545 7.088835034637367e-4 5295/374/4893/5335/7039/55824/6456/30011/2885/8874/3845/3265/5829/7314/8038/1839/5290/8027/2060/2069/102/6714/9146/6455/1445/6233/29924/5781/6464/5782/5796/998/6654/7311/1956/2549/10253/685/58513/7316/1950/867/10254/6457 44 Human_SARS_coronavirus_2 R-HSA-164952 The role of Nef in HIV-1 replication and disease pathogenesis 26/7348 27/10654 5.722017978055685e-4 0.0016672015375190003 7.173695292830956e-4 162/1174/567/2534/163/1794/55690/5062/5879/51606/161/10053/3932/1175/8907/940/1173/160/920/8905/164/919/130340/3055/9844/375 26 Human_SARS_coronavirus_2 R-HSA-912526 Interleukin receptor SHC signaling 26/7348 27/10654 5.722017978055685e-4 0.0016672015375190003 7.173695292830956e-4 5295/5777/1437/5291/3558/3717/3563/2885/9846/3635/5290/1439/3718/3567/3562/6464/1438/8503/6654/3716/5293/3561/3568/3560/5296/3559 26 Human_SARS_coronavirus_2 R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 31/7348 33/10654 5.731465470030237e-4 0.0016672015375190003 7.173695292830956e-4 23165/348995/57122/23511/23279/23225/9972/8021/55746/3303/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/3304/81929/9631/79023/23636/53371/9688/8480 31 Human_SARS_coronavirus_2 R-HSA-180746 Nuclear import of Rev protein 31/7348 33/10654 5.731465470030237e-4 0.0016672015375190003 7.173695292830956e-4 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/1104/3837/81929/9631/79023/23636/53371/9688/8480 31 Human_SARS_coronavirus_2 R-HSA-180910 Vpr-mediated nuclear import of PICs 31/7348 33/10654 5.731465470030237e-4 0.0016672015375190003 7.173695292830956e-4 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/11168/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/3159/79023/23636/53371/9688/8815/8480 31 Human_SARS_coronavirus_2 R-HSA-389356 CD28 co-stimulation 31/7348 33/10654 5.731465470030237e-4 0.0016672015375190003 7.173695292830956e-4 5295/941/2534/2885/2475/5062/5879/1326/5290/57761/9020/6714/10000/7525/7409/3932/117145/940/253260/5170/64223/8503/4067/5063/998/208/79109/5058/9402/207/5296 31 Human_SARS_coronavirus_2 R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 31/7348 33/10654 5.731465470030237e-4 0.0016672015375190003 7.173695292830956e-4 4790/4792/177/3654/7334/3551/7314/257397/8767/23118/8517/5970/10454/6233/4791/351/387522/64127/3656/7189/7311/28511/1147/6885/10392/7316/7335/4793/3146/6288/6285 31 Human_SARS_coronavirus_2 R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 20/7348 20/10654 5.88354715149916e-4 0.0016672015375190003 7.173695292830956e-4 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Human_SARS_coronavirus_2 R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 20/7348 20/10654 5.88354715149916e-4 0.0016672015375190003 7.173695292830956e-4 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Human_SARS_coronavirus_2 R-HSA-167044 Signalling to RAS 20/7348 20/10654 5.88354715149916e-4 0.0016672015375190003 7.173695292830956e-4 4893/5898/1432/5603/2885/3845/3265/5899/9261/6714/4914/5600/6300/6464/7867/6654/5900/25759/53358/4803 20 Human_SARS_coronavirus_2 R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 20/7348 20/10654 5.88354715149916e-4 0.0016672015375190003 7.173695292830956e-4 7321/7334/3551/7314/11035/8737/8517/7323/6233/387522/330/7098/7189/7311/1147/7316/7335/7322/329/148022 20 Human_SARS_coronavirus_2 R-HSA-3560801 Defective B3GAT3 causes JDSSDHD 20/7348 20/10654 5.88354715149916e-4 0.0016672015375190003 7.173695292830956e-4 10675/6385/1463/221914/6382/63827/633/375790/2262/9672/1464/2239/2719/26229/2817/3339/1634/6383/1462/10082 20 Human_SARS_coronavirus_2 R-HSA-418217 G beta:gamma signalling through PLC beta 20/7348 20/10654 5.88354715149916e-4 0.0016672015375190003 7.173695292830956e-4 2788/5331/2782/2787/10681/2792/2785/2783/2784/2791/23236/2786/54331/59345/51764/94235/5330/55970/2793/2790 20 Human_SARS_coronavirus_2 R-HSA-5213460 RIPK1-mediated regulated necrosis 20/7348 20/10654 5.88354715149916e-4 0.0016672015375190003 7.173695292830956e-4 356/7314/11035/8737/841/8797/6233/8772/331/8717/8743/330/8837/197259/7311/8795/7186/355/7316/329 20 Human_SARS_coronavirus_2 R-HSA-5218859 Regulated Necrosis 20/7348 20/10654 5.88354715149916e-4 0.0016672015375190003 7.173695292830956e-4 356/7314/11035/8737/841/8797/6233/8772/331/8717/8743/330/8837/197259/7311/8795/7186/355/7316/329 20 Human_SARS_coronavirus_2 R-HSA-5625900 RHO GTPases activate CIT 20/7348 20/10654 5.88354715149916e-4 0.0016672015375190003 7.173695292830956e-4 388/79784/4628/5879/4659/389/11113/9055/5500/10627/387/4660/4629/4627/1027/10398/4637/1742/9928/103910 20 Human_SARS_coronavirus_2 R-HSA-5627117 RHO GTPases Activate ROCKs 20/7348 20/10654 5.88354715149916e-4 0.0016672015375190003 7.173695292830956e-4 388/79784/9475/4628/6093/1072/4659/389/5500/10627/387/5058/4660/4629/3984/4627/3985/10398/4637/103910 20 Human_SARS_coronavirus_2 R-HSA-5654706 FRS-mediated FGFR3 signaling 20/7348 20/10654 5.88354715149916e-4 0.0016672015375190003 7.173695292830956e-4 4893/2250/2885/2253/3845/3265/8823/8074/2249/2247/2246/5781/6654/8822/8817/10817/2254/26281/10818/2261 20 Human_SARS_coronavirus_2 R-HSA-5654719 SHC-mediated cascade:FGFR4 20/7348 20/10654 5.88354715149916e-4 0.0016672015375190003 7.173695292830956e-4 4893/9965/2264/2885/2253/3845/3265/8823/8074/2249/2247/2246/2251/6464/6654/8822/8817/2254/152831/26281 20 Human_SARS_coronavirus_2 R-HSA-5654720 PI-3K cascade:FGFR4 20/7348 20/10654 5.88354715149916e-4 0.0016672015375190003 7.173695292830956e-4 5295/9965/2264/2885/2253/5290/8823/8074/2249/2247/2246/2251/5781/2549/8822/8817/2254/152831/26281/10818 20 Human_SARS_coronavirus_2 R-HSA-69186 Lagging Strand Synthesis 20/7348 20/10654 5.88354715149916e-4 0.0016672015375190003 7.173695292830956e-4 2237/1763/5982/5422/6117/10714/5558/6118/3978/5557/5985/5984/23649/5424/5425/5111/6119/5983/57804/5981 20 Human_SARS_coronavirus_2 R-HSA-8964616 G beta:gamma signalling through CDC42 20/7348 20/10654 5.88354715149916e-4 0.0016672015375190003 7.173695292830956e-4 2788/2782/2787/10681/2792/2785/2783/2784/2791/998/2786/5058/54331/59345/9459/51764/94235/55970/2793/2790 20 Human_SARS_coronavirus_2 R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 55/7348 63/10654 6.17284014927122e-4 0.0017456791942139008 7.511371802692138e-4 55718/4790/5435/4792/3428/1387/22954/1660/3551/7314/11035/8737/29110/81844/8517/6778/51428/5970/3661/6233/661/11128/4791/9533/3665/5434/10623/23220/7098/9208/5591/7311/81030/171568/10621/2547/28511/1147/170506/5440/6737/1499/7520/147945/5441/4615/7316/55703/27297/4793/5437/2033/11277/197358/148022 55 Human_SARS_coronavirus_2 R-HSA-373760 L1CAM interactions 98/7348 119/10654 6.529381874079284e-4 0.0018428235468958298 7.929368049622496e-4 9252/6711/71/7430/1459/51807/286/347688/1785/1460/10381/7278/8829/4684/3688/1457/285643/5605/7846/1463/3690/1808/81027/6456/1741/6709/5962/163/6196/1759/6197/8986/3312/100133941/5879/6331/161/79861/5594/6327/284217/55800/2260/3672/8650/6714/10376/6195/214/7410/51332/3685/1213/1211/1175/1173/84617/6323/6712/3674/10382/7277/6329/3678/4478/160/3912/26052/6710/10752/27330/347733/6386/1641/2048/3897/10383/24137/1956/60/84790/5058/8506/8515/7280/5595/5604/10048/11313/112714/3915/57731/3673/6708/1742/287/3680/288 98 Human_SARS_coronavirus_2 R-HSA-111465 Apoptotic cleavage of cellular proteins 35/7348 38/10654 6.753807654160234e-4 0.0018948182585282877 8.153092782173383e-4 836/324/9414/4001/6709/6093/840/2934/22985/63967/841/100506658/7082/5339/5317/28988/10134/999/5588/5580/839/1828/5747/118/1829/8428/1832/1830/4000/51765/1499/329/4137/7431/6304 35 Human_SARS_coronavirus_2 R-HSA-5689896 Ovarian tumor domain proteases 35/7348 38/10654 6.753807654160234e-4 0.0018948182585282877 8.153092782173383e-4 7321/55432/324/64135/7187/7314/8737/8767/55611/8517/80124/983/2099/23586/7128/7157/6233/55593/84282/10318/7706/79155/79589/64127/7189/7311/387/56957/10392/57506/7316/7415/5728/78990/54764 35 Human_SARS_coronavirus_2 R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 35/7348 38/10654 6.753807654160234e-4 0.0018948182585282877 8.153092782173383e-4 1912/1459/6045/80012/1460/28996/1457/1911/6603/10138/57332/57492/100532731/86/865/51412/84733/6604/8289/6602/23429/6015/6595/6597/8535/6599/648/6601/23466/6598/2033/84333/6605/861/26053 35 Human_SARS_coronavirus_2 R-HSA-381042 PERK regulates gene expression 30/7348 32/10654 7.849592716114315e-4 0.0021892157989320793 9.419837205261238e-4 5393/1965/23404/3576/3309/6347/11340/468/3484/8894/9451/8570/23016/118460/1968/5073/1051/4800/22926/51010/56915/167227/22894/440/9709/4802/1649/51013/467/54512 30 Human_SARS_coronavirus_2 R-HSA-5626467 RHO GTPases activate IQGAPs 30/7348 32/10654 7.849592716114315e-4 0.0021892157989320793 9.419837205261238e-4 71/6249/51807/347688/10381/7278/7846/81027/8826/5879/79861/999/10376/128239/801/4221/805/84617/10382/7277/347733/998/10383/60/84790/7280/1495/1499/112714/808 30 Human_SARS_coronavirus_2 R-HSA-5656169 Termination of translesion DNA synthesis 30/7348 32/10654 7.849592716114315e-4 0.0021892157989320793 9.419837205261238e-4 5982/6117/10714/7314/6118/9636/11201/5985/5984/6233/5424/124739/54107/7706/5425/5111/6119/5427/5429/9246/51426/7311/7318/5983/56655/57804/7316/5426/9100/5981 30 Human_SARS_coronavirus_2 R-HSA-6790901 rRNA modification in the nucleus and cytosol 54/7348 62/10654 7.882337260689539e-4 0.0021940206469714583 9.440511679814658e-4 55226/10528/84135/27340/55623/88745/51096/55272/51077/23160/10607/11103/6208/22984/10813/9136/6203/51504/54433/27292/56902/51602/9724/54555/10171/5822/2091/55651/55127/8602/6194/10436/9277/84128/4839/134430/92856/65083/11056/9790/55505/51202/57647/6187/79050/55813/25879/57050/1736/10199/25926/27341/6201/10885 54 Human_SARS_coronavirus_2 R-HSA-180024 DARPP-32 events 25/7348 26/10654 8.020296493526704e-4 0.0022193149201265674 9.549348796494872e-4 5530/5499/5518/5143/5515/84152/5567/5142/5573/5528/5519/801/805/5568/5566/5577/1020/5141/5516/5533/5575/5532/5576/5144/808 25 Human_SARS_coronavirus_2 R-HSA-3238698 WNT ligand biogenesis and trafficking 25/7348 26/10654 8.020296493526704e-4 0.0022193149201265674 9.549348796494872e-4 7478/81029/55737/9559/50999/8724/7476/79971/7473/7471/89780/51699/7477/7475/7481/7482/7474/7479/7480/80326/7483/51384/7472/7484/54361 25 Human_SARS_coronavirus_2 R-HSA-901042 Calnexin/calreticulin cycle 25/7348 26/10654 8.020296493526704e-4 0.0022193149201265674 9.549348796494872e-4 811/6400/51009/7314/9695/10956/91445/11253/80267/6233/55741/23193/267/6048/821/55757/56886/10206/84447/2923/7311/7844/7316/5589/11236 25 Human_SARS_coronavirus_2 R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 19/7348 19/10654 8.537525440877832e-4 0.002321550187192549 9.98925041463034e-4 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Human_SARS_coronavirus_2 R-HSA-163615 PKA activation 19/7348 19/10654 8.537525440877832e-4 0.002321550187192549 9.98925041463034e-4 107/5567/112/5573/111/196883/115/801/805/5568/113/5566/5577/109/5575/114/108/5576/808 19 Human_SARS_coronavirus_2 R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 19/7348 19/10654 8.537525440877832e-4 0.002321550187192549 9.98925041463034e-4 11065/7321/8697/51529/29945/51434/29882/996/51433/119504/7324/64682/246184/8881/10393/51343/25906/991/8556 19 Human_SARS_coronavirus_2 R-HSA-176412 Phosphorylation of the APC/C 19/7348 19/10654 8.537525440877832e-4 0.002321550187192549 9.98925041463034e-4 11065/7321/8697/51529/29945/51434/29882/996/983/51433/119504/7324/64682/246184/8881/891/10393/25906/5347 19 Human_SARS_coronavirus_2 R-HSA-392851 Prostacyclin signalling through prostacyclin receptor 19/7348 19/10654 8.537525440877832e-4 0.002321550187192549 9.98925041463034e-4 2788/2782/2787/10681/2792/2785/2783/2784/2791/2786/54331/59345/51764/94235/55970/2778/2793/5739/2790 19 Human_SARS_coronavirus_2 R-HSA-3928664 Ephrin signaling 19/7348 19/10654 8.537525440877832e-4 0.002321550187192549 9.98925041463034e-4 1947/2051/2050/2047/2534/1948/8440/8874/5062/5879/6714/1949/10627/2049/5063/6386/2048/5058/28964 19 Human_SARS_coronavirus_2 R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 19/7348 19/10654 8.537525440877832e-4 0.002321550187192549 9.98925041463034e-4 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Human_SARS_coronavirus_2 R-HSA-77595 Processing of Intronless Pre-mRNAs 19/7348 19/10654 8.537525440877832e-4 0.002321550187192549 9.98925041463034e-4 51585/81608/1477/53981/11051/8106/1478/23283/10914/10898/51692/22916/1479/79869/29894/4686/8189/10978/55339 19 Human_SARS_coronavirus_2 R-HSA-8851708 Signaling by FGFR2 IIIa TM 19/7348 19/10654 8.537525440877832e-4 0.002321550187192549 9.98925041463034e-4 5431/5435/5433/5439/5438/2247/2246/2963/5434/5436/2263/2962/5432/22916/5440/5430/5441/4686/5437 19 Human_SARS_coronavirus_2 R-HSA-6784531 tRNA processing in the nucleus 50/7348 57/10654 8.582127408701145e-4 0.002329199262169562 0.001002216313209266 23165/10557/348995/57122/23511/11260/23279/11102/23225/9972/8021/10799/51367/55746/60528/54913/10775/10940/10248/10762/1478/79042/79902/9883/10556/1653/6396/129401/79897/4928/5903/55706/7175/51095/4927/10898/5901/8086/283989/81929/9631/29894/79023/23636/53371/10978/283742/9688/51493/8480 50 Human_SARS_coronavirus_2 R-HSA-2980766 Nuclear Envelope Breakdown 46/7348 52/10654 9.169949122629082e-4 0.002483967061187265 0.0010688103635570901 23165/5579/91754/5578/348995/57122/23511/23279/23225/4001/9972/8021/55746/10762/983/79902/9883/221496/7444/2010/64900/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/5347/7112/4000/81929/9631/140609/10783/79023/23636/53371/9688/8815/23399/23592/8480 46 Human_SARS_coronavirus_2 R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 29/7348 31/10654 0.0010731485854850646 0.002868491682185031 0.0012342650132531438 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/3837/81929/9631/79023/23636/53371/9688/8480 29 Human_SARS_coronavirus_2 R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 29/7348 31/10654 0.0010731485854850646 0.002868491682185031 0.0012342650132531438 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/81929/9631/79023/23636/53371/9688/8480 29 Human_SARS_coronavirus_2 R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 29/7348 31/10654 0.0010731485854850646 0.002868491682185031 0.0012342650132531438 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/2646/79902/9883/2645/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/79023/23636/53371/9688/8480 29 Human_SARS_coronavirus_2 R-HSA-1839124 FGFR1 mutant receptor activation 29/7348 31/10654 0.0010731485854850646 0.002868491682185031 0.0012342650132531438 5295/11052/2250/9530/613/6776/11064/2885/9846/2253/7750/8805/26127/5290/8074/2260/2249/399687/2247/2246/2251/1523/9208/6774/6772/11160/8822/2254/26281 29 Human_SARS_coronavirus_2 R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 29/7348 31/10654 0.0010731485854850646 0.002868491682185031 0.0012342650132531438 3725/9252/1848/1432/6196/5518/1386/6197/51231/5515/5601/1849/5594/5528/9261/5519/5598/4208/6195/2353/5600/5602/5595/5516/1845/4205/466/1385/5599 29 Human_SARS_coronavirus_2 R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 29/7348 31/10654 0.0010731485854850646 0.002868491682185031 0.0012342650132531438 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/2646/79902/9883/2645/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/79023/23636/53371/9688/8480 29 Human_SARS_coronavirus_2 R-HSA-5654687 Downstream signaling of activated FGFR1 29/7348 31/10654 0.0010731485854850646 0.002868491682185031 0.0012342650132531438 5295/4893/2250/5335/2885/2253/3845/3265/23769/5290/8074/2260/2249/2248/2247/2246/2251/5781/6464/9365/6654/2549/8822/10817/2254/26281/10818/2255/27006 29 Human_SARS_coronavirus_2 R-HSA-1643713 Signaling by EGFR in Cancer 24/7348 25/10654 0.0011227101316241465 0.0029784467656970796 0.0012815768857090092 5295/374/4893/5335/7039/2885/3845/3265/7314/1839/5290/2069/6233/6464/6654/7311/1956/2549/11140/685/7316/1950/867/3320 24 Human_SARS_coronavirus_2 R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 24/7348 25/10654 0.0011227101316241465 0.0029784467656970796 0.0012815768857090092 51807/10381/7278/10576/7846/81027/10574/10693/79861/10575/10376/84617/10382/7277/347733/10383/84790/22948/7280/10694/112714/7203/908/6950 24 Human_SARS_coronavirus_2 R-HSA-9006335 Signaling by Erythropoietin 24/7348 25/10654 0.0011227101316241465 0.0029784467656970796 0.0012815768857090092 5295/4893/5335/5291/6776/3717/2885/2056/8660/3845/3265/1399/5290/5336/5294/2057/7409/6464/2889/4067/6654/5293/2549/23533 24 Human_SARS_coronavirus_2 R-HSA-937041 IKK complex recruitment mediated by RIP1 24/7348 25/10654 0.0011227101316241465 0.0029784467656970796 0.0012815768857090092 7321/929/7334/3551/7314/23098/11035/8737/8517/7323/6233/387522/330/7189/7311/23643/1147/7099/7316/7335/7322/329/353376/148022 24 Human_SARS_coronavirus_2 R-HSA-2243919 Crosslinking of collagen fibrils 18/7348 18/10654 0.0012388147420078677 0.003249877634877783 0.001398369145357968 84171/84695/7093/4015/1285/5118/1284/1288/7837/1286/1287/1277/7092/1282/4016/649/4017/1278 18 Human_SARS_coronavirus_2 R-HSA-5654221 Phospholipase C-mediated cascade; FGFR2 18/7348 18/10654 0.0012388147420078677 0.003249877634877783 0.001398369145357968 2250/5335/2252/2253/8823/8074/2249/2248/2247/2246/2251/2263/8822/8817/2254/26281/2255/27006 18 Human_SARS_coronavirus_2 R-HSA-5654704 SHC-mediated cascade:FGFR3 18/7348 18/10654 0.0012388147420078677 0.003249877634877783 0.001398369145357968 4893/2250/2885/2253/3845/3265/8823/8074/2249/2247/2246/6464/6654/8822/8817/2254/26281/2261 18 Human_SARS_coronavirus_2 R-HSA-5654710 PI-3K cascade:FGFR3 18/7348 18/10654 0.0012388147420078677 0.003249877634877783 0.001398369145357968 5295/2250/2885/2253/5290/8823/8074/2249/2247/2246/5781/2549/8822/8817/2254/26281/10818/2261 18 Human_SARS_coronavirus_2 R-HSA-5675482 Regulation of necroptotic cell death 18/7348 18/10654 0.0012388147420078677 0.003249877634877783 0.001398369145357968 356/7314/8737/841/8797/6233/8772/331/8717/8743/330/8837/7311/8795/7186/355/7316/329 18 Human_SARS_coronavirus_2 R-HSA-8964315 G beta:gamma signalling through BTK 18/7348 18/10654 0.0012388147420078677 0.003249877634877783 0.001398369145357968 2788/2782/2787/10681/2792/2785/2783/2784/2791/695/2786/54331/59345/51764/94235/55970/2793/2790 18 Human_SARS_coronavirus_2 R-HSA-8853659 RET signaling 37/7348 41/10654 0.001266088257845488 0.0033152755492472596 0.0014265087973385814 5295/2674/1796/5335/5291/5578/2668/2885/8660/9846/5623/5290/5567/4902/6714/5598/64096/9260/5781/6464/5568/2675/2676/5566/8503/2886/6654/5293/2549/85358/10818/53358/5979/9048/5296/2887/9046 37 Human_SARS_coronavirus_2 R-HSA-3928663 EPHA-mediated growth cone collapse 28/7348 30/10654 0.0014643949161615474 0.003813359873761377 0.001640826328470242 2042/2045/285220/79784/2534/9475/4628/6093/2046/2041/6714/1943/2043/7525/1942/25791/10627/1945/4067/2044/387/4629/4627/10398/4637/1946/103910/1969 28 Human_SARS_coronavirus_2 R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 28/7348 30/10654 0.0014643949161615474 0.003813359873761377 0.001640826328470242 4893/817/1741/6196/6197/3845/3265/5923/818/57554/5594/2902/6195/2906/801/4747/805/5170/2904/27330/816/5924/5595/815/1742/88/1385/808 28 Human_SARS_coronavirus_2 R-HSA-499943 Interconversion of nucleotide di- and triphosphates 28/7348 30/10654 0.0014643949161615474 0.003813359873761377 0.001640826328470242 56474/4832/654364/221264/7295/1841/205/1635/7296/6241/158067/203/2936/4831/4833/7298/50484/204/2745/1854/2987/51727/26289/1503/6240/4830/122481/79077 28 Human_SARS_coronavirus_2 R-HSA-3371571 HSF1-dependent transactivation 23/7348 24/10654 0.0015694230780024425 0.004079346015248996 0.0017552758109237847 817/3305/1387/2475/3306/3312/818/3303/84335/3337/3297/57521/1410/64223/3281/816/3326/3304/10728/815/3320/2033/2288 23 Human_SARS_coronavirus_2 R-HSA-1566948 Elastic fibre formation 40/7348 45/10654 0.0016257980722731492 0.004215870362950163 0.0018140200028178325 3696/7042/84171/84695/7448/3688/8076/3693/2192/4015/3690/3694/2200/84467/7040/30008/7043/11117/4238/2006/84034/2335/3685/90187/655/4052/3678/2201/652/4236/4239/5045/4237/4016/10516/4017/8425/8516/2199/2202 40 Human_SARS_coronavirus_2 R-HSA-432720 Lysosome Vesicle Biogenesis 32/7348 35/10654 0.0016308918589347519 0.004215870362950163 0.0018140200028178325 8906/162/27243/1212/1174/1785/11154/408/6456/3312/10053/9146/4074/6844/1213/1211/23431/8907/351/9179/9829/8905/8673/164/130340/1522/2799/2647/81567/10717/6845/375 32 Human_SARS_coronavirus_2 R-HSA-9615710 Microautophagy 32/7348 35/10654 0.0016308918589347519 0.004215870362950163 0.0018140200028178325 51652/27243/5116/55048/51271/3043/29082/3312/11315/92421/7314/137492/25978/51160/10013/91782/79720/89853/6233/79643/8100/1068/128866/7311/93343/7251/155382/1080/7316/10226/200894/7431 32 Human_SARS_coronavirus_2 R-HSA-164378 PKA activation in glucagon signalling 17/7348 17/10654 0.0017974727064162708 0.004571270515957926 0.0019669428707092098 107/5567/112/5573/111/196883/115/5568/113/5566/5577/109/5575/114/108/2778/5576 17 Human_SARS_coronavirus_2 R-HSA-2033519 Activated point mutants of FGFR2 17/7348 17/10654 0.0017974727064162708 0.004571270515957926 0.0019669428707092098 2250/2252/2253/8823/8074/2249/2248/2247/2246/2251/2263/8822/8817/2254/26281/2255/27006 17 Human_SARS_coronavirus_2 R-HSA-3781860 Diseases associated with N-glycosylation of proteins 17/7348 17/10654 0.0017974727064162708 0.004571270515957926 0.0019669428707092098 79053/10195/85365/79087/9526/56052/1798/4247/11253/7841/79796/79868/91869/199857/440138/2683/29929 17 Human_SARS_coronavirus_2 R-HSA-432142 Platelet sensitization by LDL 17/7348 17/10654 0.0017974727064162708 0.004571270515957926 0.0019669428707092098 5777/5526/5175/2268/1432/5518/5515/5528/5519/5781/338/5529/5516/5321/5525/5527/7804 17 Human_SARS_coronavirus_2 R-HSA-435354 Zinc transporters 17/7348 17/10654 0.0017974727064162708 0.004571270515957926 0.0019669428707092098 7779/283375/7780/55630/148867/169026/25800/7922/29985/64116/64924/23516/55676/27173/7781/29986/57181 17 Human_SARS_coronavirus_2 R-HSA-450385 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA 17/7348 17/10654 0.0017974727064162708 0.004571270515957926 0.0019669428707092098 5393/23404/11340/9261/23016/118460/677/51010/56915/167227/7529/22894/207/55802/51013/54464/54512 17 Human_SARS_coronavirus_2 R-HSA-450513 Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA 17/7348 17/10654 0.0017974727064162708 0.004571270515957926 0.0019669428707092098 5393/23404/11340/9261/23016/118460/3842/7538/51010/56915/167227/7529/22894/55802/51013/54464/54512 17 Human_SARS_coronavirus_2 R-HSA-450604 KSRP (KHSRP) binds and destabilizes mRNA 17/7348 17/10654 0.0017974727064162708 0.004571270515957926 0.0019669428707092098 5393/23404/1432/11340/7534/5600/8570/23016/118460/5073/51010/56915/167227/22894/207/51013/54512 17 Human_SARS_coronavirus_2 R-HSA-8934593 Regulation of RUNX1 Expression and Activity 17/7348 17/10654 0.0017974727064162708 0.004571270515957926 0.0019669428707092098 27327/192669/5371/4343/865/6714/595/896/26523/5781/27161/894/57690/192670/1021/861/23112 17 Human_SARS_coronavirus_2 R-HSA-375165 NCAM signaling for neurite out-growth 54/7348 63/10654 0.0018139319929199272 0.004604847105904448 0.0019813903277099464 2674/9252/4893/6711/256076/5621/1280/1289/4684/2668/1290/1463/2534/2885/6709/3845/1285/5623/3265/375790/1284/784/5594/4902/2260/1298/6714/64096/51332/1292/1293/1291/1286/1287/6712/5747/2675/6710/775/6654/5595/5786/1282/1299/776/57731/1281/1297/6708/783/1385/9048/50509/131873 54 Human_T.cell_leukemia_virus_1 R-HSA-72613 Eukaryotic Translation Initiation 116/1332 119/10654 3.652458087633422e-102 2.2973961371214223e-99 1.0015424545563226e-99 6158/8669/6138/6144/6203/6227/9349/4736/6206/8891/6194/1965/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/1983/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/6232/1967/6134/6169/6160/6164/6155/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/8890/6142/6167/7458/6204/8663/6228/23521/116832/8894/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/8893/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/1978/6161/9045/6187/6168/6208/6157/6137/6170/8892/1974/200916/6122/6133/1968/6230 116 Human_T.cell_leukemia_virus_1 R-HSA-72737 Cap-dependent Translation Initiation 116/1332 119/10654 3.652458087633422e-102 2.2973961371214223e-99 1.0015424545563226e-99 6158/8669/6138/6144/6203/6227/9349/4736/6206/8891/6194/1965/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/1983/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/6232/1967/6134/6169/6160/6164/6155/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/8890/6142/6167/7458/6204/8663/6228/23521/116832/8894/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/8893/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/1978/6161/9045/6187/6168/6208/6157/6137/6170/8892/1974/200916/6122/6133/1968/6230 116 Human_T.cell_leukemia_virus_1 R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 109/1332 112/10654 1.0916580161616512e-95 4.57768594777119e-93 1.99562746112358e-93 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/1983/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 109 Human_T.cell_leukemia_virus_1 R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 108/1332 111/10654 9.151524178487765e-95 2.878154354134402e-92 1.2547221307874015e-92 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 108 Human_T.cell_leukemia_virus_1 R-HSA-72689 Formation of a pool of free 40S subunits 98/1332 101/10654 1.4863262959731097e-85 3.739596960668344e-83 1.6302652635831372e-83 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/8663/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 98 Human_T.cell_leukemia_virus_1 R-HSA-156902 Peptide chain elongation 86/1332 89/10654 1.4668591959543424e-74 3.0755147808509376e-72 1.3407607738459867e-72 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/1938/6159/6147/6129/1915/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 86 Human_T.cell_leukemia_virus_1 R-HSA-156842 Eukaryotic Translation Elongation 88/1332 93/10654 7.283164455546948e-74 1.3088886978682944e-71 5.706058167428511e-72 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/1938/6159/6147/6129/1915/6217/1936/6222/6176/6152/6136/6125/1937/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 88 Human_T.cell_leukemia_virus_1 R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 89/1332 95/10654 1.2675561469867153e-73 1.99323204113661e-71 8.689430955001036e-72 6158/6138/6144/6203/6227/9349/4736/6206/6194/2107/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/6232/2935/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/1981/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/23708/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 89 Human_T.cell_leukemia_virus_1 R-HSA-5693532 DNA Double-Strand Break Repair 120/1332 166/10654 3.114163799006067e-72 4.352908954610702e-70 1.8976366541311824e-70 8467/51750/1017/6118/80010/54962/25/3838/2237/5893/83990/7516/5888/5892/9156/5883/322/1763/7486/10111/57804/51588/7518/7520/51720/675/7515/5982/63967/54107/5531/51548/11200/545/472/6613/80198/7336/3981/580/11073/2072/5591/29086/7316/2140/116028/2070/890/197342/9031/5425/641/5111/5426/10635/7517/64421/9656/6119/84464/3364/22976/7341/10524/4683/5427/144715/5889/55775/5429/5985/165918/84126/142/8914/1111/7157/9682/8900/5984/23514/7329/79728/8924/6233/2067/51426/146956/672/5932/7158/7311/2138/6047/9025/79184/23030/3980/5536/7156/5890/5983/6117/5599/7334/5981/10038/10714/2547/5884/5810/5424/79840/2139/348654/83695/55183/7314/56655 120 Human_T.cell_leukemia_virus_1 R-HSA-72764 Eukaryotic Translation Termination 87/1332 93/10654 8.006861953030962e-72 1.007263233691295e-69 4.3911316605569796e-70 6158/6138/6144/6203/6227/9349/4736/6206/6194/2107/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/2935/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/23708/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 87 Human_T.cell_leukemia_virus_1 R-HSA-73894 DNA Repair 174/1332 334/10654 1.842097967580271e-71 2.1066902211054372e-69 9.184048240280585e-70 9318/8467/11284/51750/1017/7014/6118/80010/54962/25/3838/2237/6917/5434/5440/5893/4436/83990/902/7516/5888/5892/9156/5883/322/1763/328/7486/5430/10111/57804/5436/51588/7518/7520/51720/2956/675/7515/5982/63967/404672/54107/7013/5531/51548/4292/11200/545/472/6613/5441/7507/7706/80198/7336/5438/3978/3981/580/5431/11073/2072/5591/29086/5435/54778/7316/2140/5433/116028/2070/890/197342/9031/4331/5425/641/5111/5426/10635/2966/7415/5395/7517/10980/64421/9656/6119/84464/3364/22976/7341/10524/4683/5437/5427/144715/1161/5889/55775/9937/2177/5429/2965/5985/2033/165918/84126/142/8914/2068/5439/1111/10987/2071/7157/9682/55215/8900/5984/23514/1069/7329/79728/8924/6233/2067/51426/2968/146956/672/5932/7158/7311/2138/6047/9025/2967/79184/23030/3980/60/5536/7156/5890/5887/5983/6117/5599/7334/5981/10038/10714/7874/2547/5884/5810/5424/79840/1022/5432/2139/348654/8178/83695/4437/55183/57697/7508/7314/8554/7528/56655 174 Human_T.cell_leukemia_virus_1 R-HSA-192823 Viral mRNA Translation 84/1332 89/10654 3.001322197466648e-70 3.146386103677536e-68 1.3716568990176522e-68 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 84 Human_T.cell_leukemia_virus_1 R-HSA-2408557 Selenocysteine synthesis 84/1332 93/10654 4.2329594595968485e-66 4.096202307825258e-64 1.7857262173683872e-64 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 84 Human_T.cell_leukemia_virus_1 R-HSA-5663205 Infectious disease 179/1332 383/10654 5.623608331815351e-64 5.053213772445508e-62 2.2029322863727805e-62 6158/5905/6138/6144/2963/3838/2237/6917/6203/5434/5440/164/5684/6227/9349/4736/902/6206/6194/6234/6191/162/6166/6128/51121/6132/5604/1499/1938/3159/6159/6147/6129/6217/2959/8027/5430/6874/6222/5436/6176/6152/6136/7518/7520/6125/821/404672/811/6749/6224/6146/51065/6154/6141/6202/6123/5441/6232/5438/6134/3978/3981/6169/5431/6160/7469/919/6164/5435/7316/6155/10213/6175/5433/6218/6872/2960/567/4331/926/6209/6193/6714/6173/6210/5605/6231/6229/11224/6205/2966/6165/6130/9150/2962/6142/6167/6204/867/5688/6228/5437/8812/23521/5687/116832/999/5685/5683/5708/3320/6455/2965/5686/2534/140801/6156/6235/905/6143/2068/6181/5439/6124/2071/6207/6827/6139/5609/6233/2885/3326/2968/7514/1025/7311/6223/25873/2967/3932/5610/6908/3921/6188/6189/7040/7251/11198/6135/6201/904/6161/7936/6829/51497/2547/9045/2961/6187/6416/1022/5432/6168/6208/1234/10254/6157/6137/8178/6170/200916/6122/6133/2957/940/7314/25920/6230 179 Human_T.cell_leukemia_virus_1 R-HSA-3700989 Transcriptional Regulation by TP53 171/1332 365/10654 3.0766595552341748e-61 2.5802918136563946e-59 1.1248699145803545e-59 1017/6118/80010/3725/9891/2963/6917/5434/5440/4436/83990/902/5892/9156/5883/1763/7531/1029/7027/7486/6446/5430/10111/9219/6874/8445/207/5436/1345/9212/57690/7832/1027/5982/404672/27327/5931/355/55367/6749/4292/11200/545/472/5441/79813/192670/5438/580/5431/7469/11073/639/5435/7316/5433/1869/891/6872/116028/890/1457/54971/4331/983/1026/54205/641/5111/1108/2966/5395/4194/9150/2962/9656/6119/1647/147923/5928/3364/1432/10524/1387/4683/5437/8812/1350/144715/57459/1616/2177/10000/6794/2965/5985/54815/51755/2033/995/84126/5728/6009/905/2068/5439/1111/192669/3066/3065/2071/7157/1107/55215/8900/5984/91875/6827/5371/23112/208/10498/6233/5527/2968/2475/672/5932/1025/2353/604/7311/7161/2967/1386/6908/4513/8851/5300/7156/5983/4343/6117/11198/50484/1327/5600/904/4697/7936/6829/26523/51497/7874/637/1020/5884/5810/53615/10397/1022/8795/5432/26013/8178/83695/10919/7314/4193/25920/1263 171 Human_T.cell_leukemia_virus_1 R-HSA-168273 Influenza Viral RNA Transcription and Replication 99/1332 134/10654 4.1954989258161386e-61 3.298711030422939e-59 1.438062460756716e-59 6158/6138/6144/2963/6203/5434/5440/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/5430/6222/5436/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/5441/6232/5438/6134/6169/5431/6160/6164/5435/6155/6175/5433/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/2962/6142/6167/6204/6228/5437/23521/116832/3320/140801/6156/6235/6143/6181/5439/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/5432/6168/6208/6157/6137/6170/200916/6122/6133/6230 99 Human_T.cell_leukemia_virus_1 R-HSA-449147 Signaling by Interleukins 195/1332 461/10654 5.859339088090027e-61 4.33591092518662e-59 1.8902264178915815e-59 5295/729230/3605/7124/2308/3725/5777/596/5684/5601/3562/351/9252/3635/6464/5290/3566/1437/3667/4790/6885/6597/2309/5291/5604/64109/9049/3561/3587/6351/3578/7184/356/6775/207/5292/5451/3684/9021/7422/3553/2625/1439/5594/8878/3595/4582/2919/821/5743/3091/3568/941/25930/10538/4318/3726/4312/3383/11009/4478/8517/6657/1438/6778/3576/3581/6810/3662/3597/6776/7316/3565/10213/6175/2920/3560/79155/6352/50615/84868/6774/4314/5970/4792/4205/5443/6850/1026/6348/9261/3718/1440/3627/7133/3606/6772/8651/8809/4609/3146/5566/149233/8503/4988/5598/3552/1432/4208/867/5688/3567/5687/466/6950/3558/4067/3717/4088/3636/836/5685/5683/5708/3320/5602/5686/4843/2335/2534/595/6195/57162/9466/3458/2002/7157/6648/942/3563/7189/6285/5609/6654/6233/2885/58985/3716/7409/8660/1385/2353/604/6196/7311/3594/1154/2939/9846/6347/3932/3575/5293/2185/1386/5296/7040/6935/3687/3588/3570/6197/5599/5600/7431/6777/7334/6356/3600/3312/1399/3559/3574/3551/6416/5781/3569/3162/1234/3586/5034/7314/3572/3596/5595 195 Human_T.cell_leukemia_virus_1 R-HSA-927802 Nonsense-Mediated Decay (NMD) 91/1332 115/10654 7.599521261852656e-61 5.031683024952969e-59 2.193546026274368e-59 6158/9887/6138/6144/6203/6227/9349/4736/6206/6194/2107/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/6232/26019/2935/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/1981/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/23708/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 91 Human_T.cell_leukemia_virus_1 R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 91/1332 115/10654 7.599521261852656e-61 5.031683024952969e-59 2.193546026274368e-59 6158/9887/6138/6144/6203/6227/9349/4736/6206/6194/2107/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/6232/26019/2935/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/1981/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/23708/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 91 Human_T.cell_leukemia_virus_1 R-HSA-168255 Influenza Life Cycle 102/1332 144/10654 5.654228548662739e-60 3.556509757108863e-58 1.5504489862385722e-58 6158/6138/6144/2963/6203/5434/5440/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/5430/6222/5436/6176/6152/6136/6125/821/811/6224/6146/51065/6154/6141/6202/6123/5441/6232/5438/6134/6169/5431/6160/6164/5435/6155/6175/5433/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/2962/6142/6167/6204/6228/5437/23521/116832/3320/140801/6156/6235/6143/6181/5439/6124/6207/6139/6233/7514/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/5432/6168/6208/6157/6137/6170/200916/6122/6133/6230 102 Human_T.cell_leukemia_virus_1 R-HSA-168254 Influenza Infection 105/1332 155/10654 1.1969690429953665e-58 7.170414552800814e-57 3.125919154890155e-57 6158/6138/6144/2963/3838/6203/5434/5440/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/5430/6222/5436/6176/6152/6136/6125/821/811/6224/6146/51065/6154/6141/6202/6123/5441/6232/5438/6134/6169/5431/6160/6164/5435/6155/6175/5433/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/2962/6142/6167/6204/6228/5437/23521/116832/3320/140801/6156/6235/6143/6181/5439/6124/6207/6139/6233/7514/7311/6223/25873/5610/3921/6188/6189/7040/6135/6201/6161/9045/6187/5432/6168/6208/6157/6137/6170/200916/6122/6133/6230 105 Human_T.cell_leukemia_virus_1 R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 87/1332 112/10654 6.014820841237105e-57 3.439383917398309e-55 1.4993883532461877e-55 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6747/6169/6160/6164/6155/6748/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6185/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 87 Human_T.cell_leukemia_virus_1 R-HSA-5693538 Homology Directed Repair 96/1332 138/10654 2.629595445435537e-55 1.4382743784164807e-53 6.270110879047665e-54 51750/1017/6118/80010/54962/25/2237/5893/83990/7516/5888/5892/9156/5883/1763/7486/10111/57804/51588/51720/675/7515/5982/63967/54107/5531/51548/545/472/6613/80198/7336/580/11073/2072/29086/7316/116028/890/197342/5425/641/5111/5426/10635/7517/9656/6119/84464/3364/7341/10524/4683/5427/144715/5889/5429/5985/165918/84126/142/8914/1111/8900/5984/23514/7329/79728/8924/6233/2067/51426/146956/672/5932/7158/7311/6047/9025/79184/3980/7156/5890/5983/6117/7334/5981/10038/10714/5884/5810/5424/348654/83695/7314/56655 96 Human_T.cell_leukemia_virus_1 R-HSA-5685942 HDR through Homologous Recombination (HRR) 64/1332 67/10654 1.3763287672509053e-54 7.214256621673495e-53 3.1450319637619374e-53 51750/6118/80010/83990/7516/5888/5892/9156/5883/1763/7486/10111/57804/675/5982/54107/545/472/80198/580/11073/7316/116028/197342/5425/641/5111/5426/10635/7517/6119/84464/3364/10524/4683/5427/144715/5889/5429/5985/84126/1111/5984/23514/79728/6233/51426/146956/672/5932/7311/7156/5890/5983/6117/5981/10714/5884/5810/5424/348654/83695/7314/56655 64 Human_T.cell_leukemia_virus_1 R-HSA-2408522 Selenoamino acid metabolism 86/1332 118/10654 2.597253013091956e-52 1.3069377161878723e-50 5.697552925561723e-51 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/9521/6129/6217/9255/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 86 Human_T.cell_leukemia_virus_1 R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 91/1332 132/10654 6.56150455126544e-52 3.174758740573817e-50 1.3840258587891882e-50 51750/1017/6118/80010/54962/25/5893/83990/7516/5888/5892/9156/5883/1763/7486/10111/57804/51588/51720/675/5982/63967/54107/5531/51548/545/472/6613/80198/7336/580/11073/2072/29086/7316/116028/890/197342/5425/641/5111/5426/10635/7517/9656/6119/84464/3364/7341/10524/4683/5427/144715/5889/5429/5985/165918/84126/8914/1111/8900/5984/23514/7329/79728/8924/6233/2067/51426/146956/672/5932/7158/7311/6047/9025/79184/7156/5890/5983/6117/7334/5981/10714/5884/5810/5424/348654/83695/7314/56655 91 Human_T.cell_leukemia_virus_1 R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 57/1332 59/10654 1.5479173737647147e-49 7.212148356281522e-48 3.1441128722472374e-48 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/8668/8667/6224/51065/8662/10480/26986/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/8665/6201/1978/6187/6208/1974/1968/6230 57 Human_T.cell_leukemia_virus_1 R-HSA-72649 Translation initiation complex formation 56/1332 58/10654 1.241936703823064e-48 5.387435770377291e-47 2.348635291077374e-47 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/8668/8667/6224/51065/8662/10480/26986/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1974/1968/6230 56 Human_T.cell_leukemia_virus_1 R-HSA-72702 Ribosomal scanning and start codon recognition 56/1332 58/10654 1.241936703823064e-48 5.387435770377291e-47 2.348635291077374e-47 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/1983/8668/8667/6224/51065/8662/10480/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1974/1968/6230 56 Human_T.cell_leukemia_virus_1 R-HSA-9010553 Regulation of expression of SLITs and ROBOs 100/1332 171/10654 4.380346158050996e-47 1.8368251556093843e-45 8.007580169630066e-46 6158/6138/6144/6203/5684/6227/9349/4736/6206/6194/2107/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/6232/26019/2935/6134/6169/6160/6164/7316/6155/10213/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/5688/6228/23521/5687/116832/5685/5683/5708/5686/1981/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/23708/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/7314/6230 100 Human_T.cell_leukemia_virus_1 R-HSA-376176 Signaling by ROBO receptors 111/1332 218/10654 4.1380575014485595e-44 1.679250431232996e-42 7.3206382283691e-43 6158/6138/6144/25/6203/5684/6227/9349/4736/6206/6194/2107/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/5567/6222/6176/6152/6136/5578/5532/5568/6125/6224/6146/51065/6154/6141/26986/6202/6123/6232/26019/2935/6134/6169/6160/6164/7316/6155/10213/6175/6218/6209/6193/6714/6173/6210/6231/6229/11224/6205/6165/5566/6130/6142/6167/6204/5688/6228/23521/5687/116832/5576/5685/5683/5708/5686/1981/140801/6156/6235/6143/6181/6124/6207/6139/6654/6233/7311/6223/25873/387/1630/3921/6188/6189/6135/6201/23708/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/7314/6230 111 Human_T.cell_leukemia_virus_1 R-HSA-2559583 Cellular Senescence 104/1332 195/10654 8.368993868309989e-44 3.290060714479365e-42 1.4342913833518109e-42 1912/1017/7014/3725/1019/5601/11065/4790/3159/246184/7290/1029/7027/7321/2146/10111/8535/6045/8697/57690/5594/1027/27327/80012/5931/5925/7013/1051/50488/472/79813/192670/3576/3490/8881/29855/7316/2114/1869/890/6774/5970/1026/9261/1911/6667/51433/4194/1031/5598/3552/5928/1432/10524/84733/4683/5602/23512/1021/119504/57332/6195/25842/192669/7157/8900/51529/23135/7324/64682/29945/10393/8091/23112/5609/6233/51434/1032/2353/51343/6196/7311/25906/57634/4343/8726/6197/29882/5599/648/5600/23466/4217/26523/3456/2113/6416/3569/10919/7314/996/6015/5595/4193 104 Human_T.cell_leukemia_virus_1 R-HSA-72766 Translation 130/1332 291/10654 1.6034669470095097e-43 6.112610361630193e-42 2.664772821026969e-42 6158/8669/6138/6144/6203/6227/9349/4736/6206/8891/6194/2107/1965/6234/27335/6191/6166/6128/51121/6132/1938/6159/6147/9521/8666/6129/1915/6217/1936/9255/6222/1983/6176/6152/6136/8668/8667/6125/1937/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/6232/1967/2935/6134/6747/6169/6160/6164/6155/6748/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/8890/6142/6167/7458/6204/51081/8663/6228/23521/116832/8894/1981/140801/6156/6235/6143/1973/6181/55173/6124/6185/6207/1977/6139/8893/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/1978/23708/6161/9045/6187/6168/6208/6157/6137/6170/8892/1974/200916/6122/6133/1968/6230 130 Human_T.cell_leukemia_virus_1 R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 49/1332 51/10654 2.5604527564634197e-42 9.473675198914653e-41 4.1300182232738137e-41 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/8668/8667/6224/51065/8662/10480/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/6204/8663/6228/8894/6235/6207/6233/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1968/6230 49 Human_T.cell_leukemia_virus_1 R-HSA-9006925 Intracellular signaling by second messengers 131/1332 305/10654 1.5255848887476372e-41 5.483387971555793e-40 2.3904653444737412e-40 5295/1912/2308/818/3725/6591/815/3838/5684/8841/5290/3667/5335/2309/5291/5468/1822/5575/23186/842/5567/2146/5978/9112/9219/8535/817/207/51564/6045/5578/57690/5594/5568/84232/1027/5582/27327/80012/930/5931/941/2064/6199/192670/5573/2100/7316/10213/1950/2263/1457/1026/1911/4734/6714/2099/1108/57167/2122/7101/5566/10014/8503/1958/5928/2932/2261/5688/84733/5159/5687/57459/5576/5685/3164/5683/5708/10000/54815/5686/2534/23512/57332/5728/6009/6615/816/3630/192669/3066/3065/7157/1107/23028/942/7189/5371/23112/208/5577/6233/5527/2885/2475/7409/8660/1385/57504/7311/3932/2931/5293/1386/1956/5296/5581/4343/8726/648/23466/26523/7874/5781/53615/814/940/7314/6015/5595/4193 131 Human_T.cell_leukemia_virus_1 R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 55/1332 65/10654 4.074369405321865e-40 1.4237657533041404e-38 6.206860994656993e-39 3725/2963/6917/5434/5440/4436/902/5892/5430/5436/404672/6749/4292/545/472/5441/5438/5431/7469/5435/5433/4331/2966/5395/9150/2962/9656/5437/8812/2177/2965/51755/905/2068/5439/1111/2071/7157/55215/6827/2968/672/1025/2353/2967/1386/11198/904/7936/6829/51497/1022/5432/8178/25920 55 Human_T.cell_leukemia_virus_1 R-HSA-5633007 Regulation of TP53 Activity 88/1332 160/10654 1.4202626453882895e-38 4.828892994320184e-37 2.10514036485718e-37 1017/6118/80010/9891/83990/9156/5883/1763/1029/7486/6446/10111/9219/6874/8445/207/9212/5982/5931/6749/11200/545/472/79813/580/11073/639/7316/6872/116028/890/1457/54971/983/641/1108/4194/6119/5928/3364/1432/10524/4683/144715/57459/1616/10000/6794/5985/54815/2033/84126/1111/3066/3065/7157/1107/8900/5984/91875/5371/208/6233/5527/2475/672/5932/7311/7161/6908/8851/5300/7156/5983/6117/11198/5600/7874/1020/5884/5810/53615/26013/83695/10919/7314/4193/1263 88 Human_T.cell_leukemia_virus_1 R-HSA-5696398 Nucleotide Excision Repair 72/1332 111/10654 1.8618741780364395e-38 6.163783463078529e-37 2.6870815699639473e-37 9318/6118/6917/5434/5440/902/5430/57804/5436/7515/5982/404672/54107/6613/5441/7507/7336/5438/3978/5431/2072/5435/54778/7316/5433/4331/5425/5111/5426/2966/10980/6119/7341/5437/5427/1161/2965/5985/2033/142/2068/5439/10987/2071/5984/1069/7329/6233/2067/51426/2968/7311/2967/3980/60/5887/5983/6117/7334/5981/10038/10714/7874/5424/1022/5432/8178/7508/7314/8554/7528/56655 72 Human_T.cell_leukemia_virus_1 R-HSA-1257604 PIP3 activates AKT signaling 114/1332 264/10654 1.893692368929267e-36 6.108371795161585e-35 2.662925031611736e-35 5295/1912/2308/3725/6591/5684/8841/5290/3667/2309/5291/5468/1822/23186/842/2146/5978/9112/9219/8535/207/51564/6045/57690/5594/84232/1027/27327/80012/930/5931/941/2064/6199/192670/2100/7316/10213/1950/2263/1457/1026/1911/4734/6714/2099/1108/57167/2122/7101/10014/8503/1958/5928/2932/2261/5688/84733/5159/5687/57459/5685/3164/5683/5708/10000/54815/5686/2534/23512/57332/5728/6009/6615/3630/192669/3066/3065/7157/1107/23028/942/7189/5371/23112/208/6233/5527/2885/2475/7409/8660/1385/57504/7311/3932/2931/5293/1386/1956/5296/4343/8726/648/23466/26523/7874/5781/53615/940/7314/6015/5595/4193 114 Human_T.cell_leukemia_virus_1 R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 41/1332 42/10654 2.0340475912619993e-36 6.397079674518987e-35 2.7887863027565837e-35 6118/80010/83990/7516/5888/5892/9156/5883/1763/7486/10111/675/5982/545/472/580/11073/116028/641/10635/7517/6119/3364/10524/4683/144715/5889/5985/84126/1111/5984/79728/672/5932/7156/5890/5983/6117/5884/5810/83695 41 Human_T.cell_leukemia_virus_1 R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 58/1332 79/10654 7.420209773305887e-36 2.27673753532166e-34 9.925364035667183e-35 9318/6118/6917/5434/5440/902/5430/57804/5436/7515/5982/404672/54107/5441/7507/5438/3978/5431/2072/5435/7316/5433/4331/5425/5111/5426/2966/10980/6119/5437/5427/1161/2965/5985/2033/2068/5439/10987/2071/5984/6233/2067/51426/2968/7311/2967/3980/5983/6117/5981/10714/7874/5424/1022/5432/8178/7314/56655 58 Human_T.cell_leukemia_virus_1 R-HSA-69242 S Phase 85/1332 161/10654 1.7828411789509158e-35 5.340033816952981e-34 2.3279705619885394e-34 1017/4172/6118/2237/1019/5684/994/11065/902/8318/246184/23594/1763/7027/7321/57804/207/8697/1027/5982/10274/54107/5925/23244/10735/4149/3978/8881/5885/7316/10213/1869/993/890/4331/1026/5425/5111/5426/4171/4609/51433/6119/5928/2932/5688/5687/5427/6502/5685/5683/5708/10000/5985/5686/990/119504/8243/9126/595/81620/8900/51529/5984/7324/64682/29945/10393/208/6233/51434/51343/7311/25906/5983/6117/29882/5981/10714/7465/5424/1022/7314/996/56655 85 Human_T.cell_leukemia_virus_1 R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 51/1332 65/10654 3.942629207800056e-34 1.1534482659098768e-32 5.028420605297012e-33 6118/6917/5434/5440/902/5430/57804/5436/7515/5982/404672/54107/5441/5438/3978/5431/5435/7316/5433/4331/5425/5111/5426/2966/6119/5437/5427/1161/2965/5985/2033/2068/5439/2071/5984/6233/51426/2968/7311/2967/3980/5983/6117/5981/10714/7874/5424/1022/5432/7314/56655 51 Human_T.cell_leukemia_virus_1 R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 90/1332 185/10654 7.3544485669227e-34 2.1027037039065354e-32 9.166669146810352e-33 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/25879/6129/6217/6222/6176/6152/6136/10528/84135/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/83732/3921/6188/6189/6135/6201/6161/1453/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/9188/6230 90 Human_T.cell_leukemia_virus_1 R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 38/1332 39/10654 1.045037100990822e-33 2.921459273436565e-32 1.2736007710320895e-32 6118/80010/83990/7516/5888/5892/9156/5883/1763/7486/10111/675/5982/545/472/580/11073/116028/641/6119/3364/10524/4683/144715/5889/5985/84126/1111/5984/672/5932/7156/5890/5983/6117/5884/5810/83695 38 Human_T.cell_leukemia_virus_1 R-HSA-6782135 Dual incision in TC-NER 51/1332 66/10654 1.5290853206584054e-33 4.181715942148422e-32 1.8230056111282134e-32 6118/6917/5434/5440/902/5430/57804/5436/5982/404672/54107/5441/7507/5438/5431/2072/5435/7316/5433/4331/5425/5111/5426/2966/6119/5437/5427/1161/2965/5985/2033/2068/5439/2071/5984/6233/2067/51426/2968/7311/2967/5983/6117/5981/10714/7874/5424/1022/5432/7314/56655 51 Human_T.cell_leukemia_virus_1 R-HSA-5663202 Diseases of signal transduction 136/1332 377/10654 2.9843702797493464e-33 7.987952791329102e-32 3.482322319707524e-32 5295/2308/818/2963/815/5434/5440/5684/4893/6464/8841/5290/3667/5335/1487/2309/5291/5604/1499/10018/9734/10142/55869/842/5430/817/207/51564/5436/55534/5594/1027/930/84441/941/10013/2064/5441/6199/10046/5438/5431/6776/2100/5435/7316/10213/5433/1950/9611/8546/6774/2263/9612/1026/1024/6772/6714/2099/6934/5605/4609/7415/4089/10014/2962/22938/8850/8503/2932/2261/867/5688/1387/5437/5159/5687/3717/4088/5685/2244/3164/5683/5708/10000/3320/5686/2335/2534/2033/408/55294/5728/1445/11064/5439/816/3066/3065/4087/942/208/9794/6654/6233/5527/2885/1488/2475/7409/8660/1385/7311/8826/9846/3932/2931/5293/7450/1956/60/5296/7040/3845/6777/3265/3516/5781/4851/5432/7750/5245/940/7314/5595/4193 136 Human_T.cell_leukemia_virus_1 R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 66/1332 108/10654 5.3400016191198354e-33 1.3995254243443234e-31 6.101186060441741e-32 5295/3605/7124/2308/596/3566/2309/3561/7184/356/207/5292/5451/3684/9021/7422/3553/2625/4582/5743/3091/10538/4318/3726/4312/3383/6657/6778/3576/3662/3597/3565/6774/4314/5443/1026/3718/7133/3606/6772/8651/4609/149233/4988/3552/3717/3320/4843/2335/595/7157/3716/2353/604/6347/7040/6935/3687/3570/7431/6356/3312/3569/3162/3586/3596 66 Human_T.cell_leukemia_virus_1 R-HSA-8868773 rRNA processing in the nucleus and cytosol 91/1332 195/10654 1.967667781644501e-32 5.051685855732208e-31 2.2022661959973897e-31 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/25879/6129/6217/6222/6176/6152/6136/10528/84135/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/1736/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/83732/3921/6188/6189/6135/6201/6161/1453/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/9188/6230 91 Human_T.cell_leukemia_virus_1 R-HSA-451927 Interleukin-2 family signaling 40/1332 44/10654 3.6961488359178884e-32 9.299510471169407e-31 4.0540916705541475e-31 5295/5777/3562/3635/6464/5290/1437/5291/3561/3578/6775/1439/3568/1438/3581/6776/3560/50615/84868/6774/6850/3718/6772/8503/3567/3558/3717/3636/3563/6654/2885/3716/9846/3932/5293/2185/5296/6777/3600/3559 40 Human_T.cell_leukemia_virus_1 R-HSA-2262752 Cellular responses to stress 156/1332 479/10654 3.832092482397415e-32 9.452494789913624e-31 4.12078469211363e-31 1912/1017/818/7014/6118/3725/815/1019/5684/5601/11065/573/4790/3159/246184/112399/7531/7290/1029/7027/1915/7321/2146/10111/8535/817/6045/7422/8697/57690/5594/3308/1027/27327/80012/5931/5925/3091/7013/1051/10013/50488/545/472/79813/192670/3576/3490/8881/29855/7316/10213/2114/1869/890/6774/5970/1026/9261/1911/54205/6667/7415/51433/4194/1031/6119/5598/3552/5928/1432/2932/10524/5688/1387/84733/4683/5687/57805/2908/5685/5683/3309/5708/3320/5602/5686/2033/23512/1021/119504/7266/57332/6195/6009/25842/3301/816/7428/192669/7157/8900/51529/6648/23135/7324/64682/29945/10393/8091/23112/5609/6233/2056/51434/3326/2475/1032/2353/51343/6196/7311/367/25906/2034/57634/23411/84790/4343/8726/55662/6117/6197/29882/5599/648/5600/3312/23466/4217/26523/3456/2113/405/6416/3569/5034/10919/768/10728/7314/996/6015/5595/4193/2950 156 Human_T.cell_leukemia_virus_1 R-HSA-5685938 HDR through Single Strand Annealing (SSA) 36/1332 37/10654 6.65951410426911e-32 1.6110901429174117e-30 7.023495644380985e-31 6118/80010/25/5893/83990/5888/9156/5883/1763/7486/10111/5982/545/472/580/11073/2072/116028/641/6119/3364/10524/4683/144715/5985/84126/5984/2067/672/5932/7156/5983/6117/5884/5810/83695 36 Human_T.cell_leukemia_virus_1 R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 59/1332 92/10654 2.732847965974268e-31 6.486646681501187e-30 2.827832751286184e-30 1017/6118/80010/9891/83990/9156/5883/1763/7486/10111/6874/8445/9212/5982/6749/11200/545/472/580/11073/7316/6872/116028/890/1457/641/4194/6119/3364/1432/10524/4683/144715/6794/5985/84126/1111/7157/8900/5984/6233/672/5932/7311/6908/8851/5300/7156/5983/6117/11198/5600/1020/5884/5810/83695/7314/4193/1263 59 Human_T.cell_leukemia_virus_1 R-HSA-6807070 PTEN Regulation 74/1332 140/10654 4.7730823833685005e-31 1.1119514144958471e-29 4.847516416637405e-30 1912/3725/6591/5684/8841/5468/1822/23186/2146/5978/9112/9219/8535/207/51564/6045/57690/5594/84232/27327/80012/5931/192670/7316/10213/1457/1911/4734/1108/57167/2122/7101/10014/1958/5928/5688/84733/5687/57459/5685/5683/5708/10000/54815/5686/23512/57332/5728/6009/6615/192669/3066/3065/7157/1107/23028/5371/23112/208/6233/2475/57504/7311/1386/4343/8726/648/23466/26523/7874/53615/7314/6015/5595 74 Human_T.cell_leukemia_virus_1 R-HSA-8943724 Regulation of PTEN gene transcription 47/1332 61/10654 6.770557780241083e-31 1.5486112159169604e-29 6.751120772259531e-30 1912/3725/6591/8841/5468/1822/23186/2146/5978/9112/9219/8535/51564/6045/5594/84232/80012/5931/1911/1108/57167/2122/7101/10014/1958/5928/84733/57459/54815/23512/57332/6009/6615/3066/3065/7157/1107/23028/2475/57504/1386/8726/648/23466/53615/6015/5595 47 Human_T.cell_leukemia_virus_1 R-HSA-8953897 Cellular responses to external stimuli 156/1332 493/10654 1.5643742668086476e-30 3.514255049366569e-29 1.532028182344559e-29 1912/1017/818/7014/6118/3725/815/1019/5684/5601/11065/573/4790/3159/246184/112399/7531/7290/1029/7027/1915/7321/2146/10111/8535/817/6045/7422/8697/57690/5594/3308/1027/27327/80012/5931/5925/3091/7013/1051/10013/50488/545/472/79813/192670/3576/3490/8881/29855/7316/10213/2114/1869/890/6774/5970/1026/9261/1911/54205/6667/7415/51433/4194/1031/6119/5598/3552/5928/1432/2932/10524/5688/1387/84733/4683/5687/57805/2908/5685/5683/3309/5708/3320/5602/5686/2033/23512/1021/119504/7266/57332/6195/6009/25842/3301/816/7428/192669/7157/8900/51529/6648/23135/7324/64682/29945/10393/8091/23112/5609/6233/2056/51434/3326/2475/1032/2353/51343/6196/7311/367/25906/2034/57634/23411/84790/4343/8726/55662/6117/6197/29882/5599/648/5600/3312/23466/4217/26523/3456/2113/405/6416/3569/5034/10919/768/10728/7314/996/6015/5595/4193/2950 156 Human_T.cell_leukemia_virus_1 R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 41/1332 48/10654 1.6701173407893937e-30 3.685978271426416e-29 1.6068903685157417e-29 5295/5777/3562/3635/6464/5290/1437/5291/3561/1439/3568/1438/6776/7316/3560/6850/3718/5566/8503/867/3567/3558/4067/3717/3636/2534/3563/6654/6233/2885/3716/7409/7311/9846/5293/5296/6777/1399/3559/5781/7314 41 Human_T.cell_leukemia_virus_1 R-HSA-72312 rRNA processing 91/1332 205/10654 2.4033376646082683e-30 5.212756520822762e-29 2.272484434230323e-29 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/25879/6129/6217/6222/6176/6152/6136/10528/84135/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/1736/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/83732/3921/6188/6189/6135/6201/6161/1453/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/9188/6230 91 Human_T.cell_leukemia_virus_1 R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 55/1332 84/10654 6.125443000325388e-30 1.306069032950735e-28 5.693765928937604e-29 9318/6118/902/57804/7515/5982/404672/54107/6613/7507/7336/3978/2072/54778/7316/4331/5425/5111/5426/2966/10980/6119/7341/5427/2965/5985/142/2068/10987/2071/5984/1069/7329/6233/2067/51426/2968/7311/2967/3980/60/5887/5983/6117/7334/5981/10038/10714/5424/1022/7508/7314/8554/7528/56655 55 Human_T.cell_leukemia_virus_1 R-HSA-8939211 ESR-mediated signaling 94/1332 223/10654 3.6025536172322286e-29 7.553354084130239e-28 3.292860411540335e-28 5295/3727/3725/2354/2963/3838/596/5434/5440/5590/4893/6464/5290/2309/7031/8204/5430/207/5436/5451/2625/57690/5594/6722/1027/3315/27327/10274/51523/4318/5441/10735/192670/5438/5431/5885/2100/5435/5433/1950/865/5469/4314/6667/6714/2099/4609/2494/2962/8850/8503/10524/1387/5437/10000/3320/2033/8243/4846/9126/595/5439/192669/3065/2002/861/23028/23112/208/10498/3326/7514/1385/1025/2353/23030/1386/6908/1956/5536/3169/5296/4343/3845/904/3265/26523/8202/5432/8648/10728/2957/5595/7528 94 Human_T.cell_leukemia_virus_1 R-HSA-5693607 Processing of DNA double-strand break ends 59/1332 98/10654 4.140410488935013e-29 8.538748188656142e-28 3.7224398010960175e-28 1017/6118/80010/54962/83990/9156/5883/1763/7486/10111/51588/51720/5982/63967/5531/51548/545/472/6613/7336/580/11073/29086/7316/116028/890/641/9656/6119/3364/7341/10524/4683/144715/5985/165918/84126/8914/1111/8900/5984/7329/8924/6233/672/5932/7158/7311/6047/9025/79184/7156/5983/6117/7334/5884/5810/83695/7314 59 Human_T.cell_leukemia_virus_1 R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 83/1332 182/10654 8.974148166641413e-29 1.8208836118765963e-27 7.938083522614901e-28 1912/7020/23468/7150/5905/5893/1487/83746/5468/1029/8204/7486/1788/9112/8535/51564/6045/9212/51588/7518/80012/7153/10274/6613/10735/2516/8517/5465/5885/4929/5970/4792/9612/1911/641/23137/5111/2099/2494/9656/7341/1387/84733/1616/1789/2908/2033/23512/165918/8243/9126/57332/142/7067/7428/3066/3065/23314/7157/1107/1069/7329/5371/8924/672/7158/10155/367/9063/6117/7690/648/11315/8648/7421/6304/4286/10891/10062/7508/6015/4193/8554 83 Human_T.cell_leukemia_virus_1 R-HSA-2990846 SUMOylation 83/1332 188/10654 1.4892849683307134e-27 2.9738420478730755e-26 1.2964368730163772e-26 1912/7020/23468/7150/5905/5893/1487/83746/5468/1029/8204/7486/1788/9112/8535/51564/6045/9212/51588/7518/80012/7153/10274/6613/10735/2516/8517/5465/5885/4929/5970/4792/9612/1911/641/23137/5111/2099/2494/9656/7341/1387/84733/1616/1789/2908/2033/23512/165918/8243/9126/57332/142/7067/7428/3066/3065/23314/7157/1107/1069/7329/5371/8924/672/7158/10155/367/9063/6117/7690/648/11315/8648/7421/6304/4286/10891/10062/7508/6015/4193/8554 83 Human_T.cell_leukemia_virus_1 R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 39/1332 48/10654 1.9921837981734977e-27 3.9158862782847814e-26 1.707118024421698e-26 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/5433/4331/2966/9150/2962/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/8178/25920 39 Human_T.cell_leukemia_virus_1 R-HSA-113418 Formation of the Early Elongation Complex 31/1332 33/10654 3.0610350903597804e-26 5.834518399503945e-25 2.543539524844411e-25 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/7469/5435/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/2967/7936/6829/51497/1022/5432/25920 31 Human_T.cell_leukemia_virus_1 R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 31/1332 33/10654 3.0610350903597804e-26 5.834518399503945e-25 2.543539524844411e-25 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/7469/5435/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/2967/7936/6829/51497/1022/5432/25920 31 Human_T.cell_leukemia_virus_1 R-HSA-167169 HIV Transcription Elongation 37/1332 46/10654 8.802653451073174e-26 1.6048895712246454e-24 6.99646445157761e-25 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/8178/25920 37 Human_T.cell_leukemia_virus_1 R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 37/1332 46/10654 8.802653451073174e-26 1.6048895712246454e-24 6.99646445157761e-25 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/8178/25920 37 Human_T.cell_leukemia_virus_1 R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 37/1332 46/10654 8.802653451073174e-26 1.6048895712246454e-24 6.99646445157761e-25 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/8178/25920 37 Human_T.cell_leukemia_virus_1 R-HSA-5693537 Resolution of D-Loop Structures 31/1332 34/10654 3.057614207109346e-25 5.494969532205082e-24 2.395514288577398e-24 51750/80010/83990/7516/5888/5892/9156/1763/7486/10111/675/472/80198/580/116028/197342/641/10635/7517/84464/10524/4683/5889/23514/79728/146956/672/5932/7156/5890/348654 31 Human_T.cell_leukemia_virus_1 R-HSA-912526 Interleukin receptor SHC signaling 27/1332 27/10654 3.2952032131540106e-25 5.838543157954571e-24 2.5452941053420897e-24 5295/5777/3562/3635/6464/5290/1437/5291/3561/1439/3568/1438/3560/3718/8503/3567/3558/3717/3636/3563/6654/2885/3716/9846/5293/5296/3559 27 Human_T.cell_leukemia_virus_1 R-HSA-9006931 Signaling by Nuclear Receptors 105/1332 299/10654 1.0733688266678473e-24 1.8754138665946555e-23 8.175806413654218e-24 5295/3727/3725/2354/2963/3838/596/5434/5440/5590/4893/6464/8841/5290/1374/2309/7031/5160/8204/5430/207/5436/5451/2625/57690/5594/6722/1027/3315/27327/10274/51523/4318/5441/10735/6720/192670/5438/348/5431/5885/2100/5435/5433/1950/9611/865/5469/2874/4314/9612/6667/6714/2099/4609/2494/2962/8850/8503/10524/1387/5437/10000/3320/2033/5162/8243/4846/9126/595/5439/192669/3065/2002/9682/861/23028/23112/208/10498/3326/7514/1385/1025/2353/23030/1386/6908/1956/5536/3169/5296/4343/3845/904/3265/26523/8202/5432/8648/10728/2957/10062/5595/7528 105 Human_T.cell_leukemia_virus_1 R-HSA-5696400 Dual Incision in GG-NER 34/1332 41/10654 1.269872630658837e-24 2.1883558484504343e-23 9.540066915259612e-24 6118/57804/5982/404672/54107/7507/2072/7316/5425/5111/5426/2966/6119/5427/2965/5985/142/2068/2071/5984/6233/2067/51426/2968/7311/2967/5983/6117/5981/10038/10714/5424/7314/56655 34 Human_T.cell_leukemia_virus_1 R-HSA-5693568 Resolution of D-loop Structures through Holliday Junction Intermediates 30/1332 33/10654 2.2751414664364336e-24 3.867740492941937e-23 1.6861290242011122e-23 80010/83990/7516/5888/5892/9156/1763/7486/10111/675/472/80198/580/116028/197342/641/10635/7517/84464/10524/4683/5889/23514/79728/146956/672/5932/7156/5890/348654 30 Human_T.cell_leukemia_virus_1 R-HSA-69620 Cell Cycle Checkpoints 103/1332 293/10654 2.7894412470456617e-24 4.67882278504459e-23 2.0397177399449682e-23 1017/4172/6118/5905/80010/5684/83990/11065/8318/9156/246184/23594/5883/1763/7531/1029/7486/7321/10111/8697/9212/51588/51720/1027/5982/63967/11200/545/472/7336/6232/580/8881/11073/29086/7316/10213/891/993/5501/116028/890/983/1026/641/4171/51433/4194/9656/6119/3364/7341/10524/5688/4683/699/5687/144715/5685/5683/5708/5985/5686/990/995/119504/165918/84126/1111/7157/8900/51529/5984/7324/64682/29945/10393/8924/6233/5527/51434/672/7514/5932/7158/7311/9025/79184/25906/5347/57551/7156/5983/6117/29882/7334/7465/5884/5810/83695/7314/996/4193 103 Human_T.cell_leukemia_virus_1 R-HSA-167172 Transcription of the HIV genome 46/1332 73/10654 3.578425322182653e-24 5.92323559908655e-23 2.582215502572247e-23 2963/6917/5434/5440/902/2959/5430/6874/5436/404672/6749/5441/5438/5431/7469/5435/5433/6872/2960/4331/2966/9150/2962/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/2967/6908/11198/904/7936/6829/51497/2961/1022/5432/8178/2957/25920 46 Human_T.cell_leukemia_virus_1 R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 25/1332 25/10654 2.1807575800254623e-23 3.5628480982753655e-22 1.553212165677739e-22 6118/57804/7515/5982/54107/3978/7316/5425/5111/5426/6119/5427/5985/5984/6233/51426/7311/3980/5983/6117/5981/10714/5424/7314/56655 25 Human_T.cell_leukemia_virus_1 R-HSA-69239 Synthesis of DNA 59/1332 119/10654 4.251601661710564e-23 6.857070372348576e-22 2.9893177675454843e-22 1017/4172/6118/2237/5684/11065/8318/246184/23594/1763/7321/57804/8697/5982/54107/3978/8881/7316/10213/890/5425/5111/5426/4171/51433/6119/5688/5687/5427/6502/5685/5683/5708/5985/5686/990/119504/81620/8900/51529/5984/7324/64682/29945/10393/6233/51434/51343/7311/25906/5983/6117/29882/5981/10714/5424/7314/996/56655 59 Human_T.cell_leukemia_virus_1 R-HSA-69306 DNA Replication 61/1332 127/10654 6.53756411605045e-23 1.0410450199989197e-21 4.538402271102312e-22 1017/4172/6118/2237/5684/11065/8318/246184/23594/1763/7321/57804/8697/5982/54107/3978/8881/7316/10213/1869/890/5425/5111/5426/4171/51433/51053/6119/5688/5687/5427/6502/5685/5683/5708/5985/5686/990/119504/81620/8900/51529/5984/7324/64682/29945/10393/6233/51434/51343/7311/25906/5983/6117/29882/5981/10714/5424/7314/996/56655 61 Human_T.cell_leukemia_virus_1 R-HSA-69481 G2/M Checkpoints 71/1332 168/10654 2.3432004121458057e-22 3.68468264809928e-21 1.6063255456946907e-21 1017/4172/6118/80010/5684/83990/8318/9156/23594/5883/1763/7531/7486/10111/51588/51720/5982/63967/11200/545/472/7336/580/11073/29086/7316/10213/891/993/116028/983/641/4171/9656/6119/3364/7341/10524/5688/4683/5687/144715/5685/5683/5708/5985/5686/990/995/165918/84126/1111/7157/5984/8924/6233/672/5932/7158/7311/9025/79184/7156/5983/6117/7334/7465/5884/5810/83695/7314 71 Human_T.cell_leukemia_virus_1 R-HSA-69473 G2/M DNA damage checkpoint 51/1332 95/10654 3.6664240410660376e-22 5.694273387235895e-21 2.4824001629569927e-21 6118/80010/83990/9156/5883/1763/7531/7486/10111/51588/51720/5982/11200/545/472/7336/580/11073/29086/891/116028/983/641/9656/6119/3364/7341/10524/4683/144715/5985/995/165918/84126/1111/7157/5984/8924/672/5932/7158/9025/79184/7156/5983/6117/7334/7465/5884/5810/83695 51 Human_T.cell_leukemia_virus_1 R-HSA-112382 Formation of RNA Pol II elongation complex 40/1332 61/10654 3.8641424241435036e-22 5.856736348882564e-21 2.553225368394122e-21 2963/6917/5434/5440/902/5430/5436/404672/79577/6749/5441/5438/5431/7469/5435/5433/4331/2966/9150/2962/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/8178/25920 40 Human_T.cell_leukemia_virus_1 R-HSA-75955 RNA Polymerase II Transcription Elongation 40/1332 61/10654 3.8641424241435036e-22 5.856736348882564e-21 2.553225368394122e-21 2963/6917/5434/5440/902/5430/5436/404672/79577/6749/5441/5438/5431/7469/5435/5433/4331/2966/9150/2962/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/8178/25920 40 Human_T.cell_leukemia_virus_1 R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 25/1332 26/10654 4.99957499617114e-22 7.487458744265825e-21 3.264133550131784e-21 51750/80010/83990/7516/5888/5892/9156/1763/7486/10111/675/472/580/116028/641/10635/7517/10524/4683/5889/79728/672/5932/7156/5890 25 Human_T.cell_leukemia_virus_1 R-HSA-674695 RNA Polymerase II Pre-transcription Events 47/1332 84/10654 1.5308060448488563e-21 2.2655929463763075e-20 9.876779558715222e-21 2963/6917/5434/5440/902/2959/5430/6874/5436/404672/79577/6749/5441/5438/5431/7469/5435/5433/6872/2960/4331/2966/9150/2962/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/2967/6908/11198/904/7936/6829/51497/2961/1022/5432/8178/2957/25920 47 Human_T.cell_leukemia_virus_1 R-HSA-9018519 Estrogen-dependent gene expression 65/1332 150/10654 2.819886503099605e-21 4.124903745231748e-20 1.7982385166644975e-20 3727/3725/2354/2963/3838/596/5434/5440/7031/8204/5430/5436/5451/2625/57690/27327/10274/51523/5441/10735/192670/5438/5431/5885/5435/5433/865/5469/6667/2099/4609/2494/2962/8850/10524/1387/5437/3320/2033/8243/9126/595/5439/192669/3065/861/23028/23112/10498/3326/1025/2353/23030/1386/6908/3169/4343/904/26523/8202/5432/8648/10728/2957/7528 65 Human_T.cell_leukemia_virus_1 R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 25/1332 27/10654 5.9514874882000736e-21 8.507921886540559e-20 3.7090011738663146e-20 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/5433/4331/2966/2962/5437/2965/2068/5439/2071/2968/2967/6829/1022/5432 25 Human_T.cell_leukemia_virus_1 R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 25/1332 27/10654 5.9514874882000736e-21 8.507921886540559e-20 3.7090011738663146e-20 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/5433/4331/2966/2962/5437/2965/2068/5439/2071/2968/2967/6829/1022/5432 25 Human_T.cell_leukemia_virus_1 R-HSA-5696395 Formation of Incision Complex in GG-NER 32/1332 43/10654 1.3102947620855658e-20 1.8520795625883616e-19 8.074081266074274e-20 6118/902/404672/6613/7507/7336/2072/54778/7316/4331/2966/6119/7341/2965/142/2068/2071/1069/7329/6233/2067/2968/7311/2967/5887/6117/7334/10038/1022/7508/7314/8554 32 Human_T.cell_leukemia_virus_1 R-HSA-167287 HIV elongation arrest and recovery 29/1332 36/10654 1.7140484746458947e-20 2.369530748466523e-19 1.0329893062932461e-19 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/7469/5435/5433/9150/2962/5437/8812/905/5439/6827/1025/11198/904/7936/6829/51497/5432/8178/25920 29 Human_T.cell_leukemia_virus_1 R-HSA-167290 Pausing and recovery of HIV elongation 29/1332 36/10654 1.7140484746458947e-20 2.369530748466523e-19 1.0329893062932461e-19 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/7469/5435/5433/9150/2962/5437/8812/905/5439/6827/1025/11198/904/7936/6829/51497/5432/8178/25920 29 Human_T.cell_leukemia_virus_1 R-HSA-453279 Mitotic G1-G1/S phases 63/1332 149/10654 5.536569224633858e-20 7.570656613684123e-19 3.300403393631854e-19 1017/4172/6118/25/1019/5684/902/8318/23594/1029/7027/207/1027/7153/54107/5925/4149/7316/10213/1869/891/993/890/1876/4331/983/1026/5111/5426/6714/4171/4609/51053/1031/6119/5928/5688/5687/5427/4067/3717/6502/5685/5683/5708/10000/5686/990/1021/595/81620/3065/8900/208/6233/1032/7311/6117/7465/1022/1859/7314/56655 63 Human_T.cell_leukemia_virus_1 R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 59/1332 134/10654 7.681774222713936e-20 1.0391045131370033e-18 4.529942693869791e-19 5295/3725/5684/5601/4893/6464/4773/5290/2205/5335/4790/6885/5291/4772/7321/3937/5532/5594/4775/4214/2206/8517/5530/7316/10213/5970/4792/6850/8915/5688/5687/4067/5588/5685/5683/5708/5602/5686/2534/695/7189/5609/6654/6233/2885/7409/2353/7311/9846/5296/3845/5599/7334/3265/3551/6416/2207/7314/5595 59 Human_T.cell_leukemia_virus_1 R-HSA-2559585 Oncogene Induced Senescence 27/1332 33/10654 1.7136081032313525e-19 2.2933180785798315e-18 9.9976463805547e-19 1019/1029/7027/57690/5594/27327/5925/192670/7316/2114/1869/6667/4194/1031/1021/192669/7157/23112/6233/1032/7311/4343/26523/2113/7314/5595/4193 27 Human_T.cell_leukemia_virus_1 R-HSA-8878171 Transcriptional regulation by RUNX1 83/1332 239/10654 2.268286677494698e-19 3.0036890950403476e-18 1.3094485972019256e-18 1912/9070/25/5684/3562/4773/902/2624/1437/11091/5579/6597/8535/8085/6045/9021/2625/57690/5929/27327/80012/6598/6599/192670/7316/10213/865/1457/4331/1911/10413/51412/6714/2099/8850/5688/1387/84733/5687/3558/5588/5685/6604/5683/8289/5708/5686/10138/2033/1021/6605/6602/57332/595/50943/3458/192669/3065/83737/861/5371/23112/6233/9757/7311/6688/7161/860/58508/4343/648/8784/6601/3559/23466/26523/5781/7057/1022/1493/4297/7314/6015 83 Human_T.cell_leukemia_virus_1 R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 22/1332 23/10654 2.370164264013315e-19 3.1059027543007814e-18 1.3540083131040977e-18 11065/246184/7321/8697/8881/7316/891/983/51433/119504/51529/7324/64682/29945/10393/6233/51434/7311/25906/29882/7314/996 22 Human_T.cell_leukemia_virus_1 R-HSA-72086 mRNA Capping 25/1332 29/10654 3.1313892310063913e-19 4.061121291346433e-18 1.770432761100738e-18 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/5433/4331/2966/2962/5437/2965/2068/5439/2071/2968/2967/6829/1022/5432 25 Human_T.cell_leukemia_virus_1 R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 27/1332 34/10654 7.338148728319954e-19 9.324637474976264e-18 4.065045707022537e-18 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/7469/5435/5433/9150/2962/5437/5439/6827/1025/11198/904/7936/6829/51497/5432/8178/25920 27 Human_T.cell_leukemia_virus_1 R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 27/1332 34/10654 7.338148728319954e-19 9.324637474976264e-18 4.065045707022537e-18 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/7469/5435/5433/9150/2962/5437/5439/6827/1025/11198/904/7936/6829/51497/5432/8178/25920 27 Human_T.cell_leukemia_virus_1 R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 34/1332 54/10654 3.5124757068034924e-18 4.418694439158794e-17 1.9263156244680208e-17 9318/6917/5434/5440/902/5430/5436/404672/5441/7507/5438/5431/5435/7316/5433/4331/2966/10980/5437/1161/2965/2033/2068/5439/10987/2071/6233/2968/7311/2967/7874/1022/5432/7314 34 Human_T.cell_leukemia_virus_1 R-HSA-166520 Signaling by NTRKs 48/1332 101/10654 4.6861835848404574e-18 5.814789913755487e-17 2.5349389549549065e-17 5295/627/5800/9252/4893/6464/5290/3667/5335/4915/5291/5604/2904/135/5594/6774/4205/9261/6714/5605/5598/1432/4208/466/4914/2534/6195/4803/5603/2002/6654/2885/8660/1385/6196/387/8851/5296/6197/3845/5600/3265/1399/6300/1020/5781/5595/25920 48 Human_T.cell_leukemia_virus_1 R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 127/1332 473/10654 4.714694524666611e-18 5.814789913755487e-17 2.5349389549549065e-17 5295/54106/3675/5777/627/2963/5434/5440/5800/5590/9252/4893/6464/5290/3667/5335/5579/4915/5291/5604/1499/2904/5567/8027/5430/135/10048/207/5436/7422/5578/5594/5568/3315/51741/4318/2064/5441/6778/5438/348/5431/6776/5435/7316/5433/1950/9611/5327/6774/2263/4205/9261/4734/10413/6772/6714/2099/8651/5605/5566/2962/8503/5598/1432/2261/4208/867/5437/5159/466/4670/4067/3717/4914/10000/3320/6455/2335/2534/4846/6195/4803/1445/5439/1111/5603/3630/2002/83737/6285/208/6654/6233/2885/2475/7409/8660/1385/6196/7311/9846/3932/3479/2185/387/1956/60/8851/5296/5581/6197/3845/10076/5600/6777/3265/1399/6300/1020/5781/7057/5432/10254/7314/5595/25920 127 Human_T.cell_leukemia_virus_1 R-HSA-162587 HIV Life Cycle 61/1332 152/10654 4.891038417934282e-18 5.973714883263425e-17 2.6042217841019526e-17 5905/2963/2237/6917/5434/5440/902/3159/2959/5430/6874/5436/7518/7520/404672/6749/5441/5438/3978/3981/5431/7469/5435/7316/5433/6872/2960/4331/2966/9150/2962/5437/8812/2965/905/2068/5439/2071/6827/6233/2968/7514/1025/7311/2967/6908/7251/11198/904/7936/6829/51497/2547/2961/1022/5432/1234/8178/2957/7314/25920 61 Human_T.cell_leukemia_virus_1 R-HSA-176412 Phosphorylation of the APC/C 19/1332 19/10654 6.220134366877289e-18 7.523970224549645e-17 3.280050612492984e-17 11065/246184/7321/8697/8881/891/983/51433/119504/51529/7324/64682/29945/10393/51434/25906/5347/29882/996 19 Human_T.cell_leukemia_virus_1 R-HSA-5683057 MAPK family signaling cascades 92/1332 294/10654 6.6708991608938964e-18 7.992372518480497e-17 3.4842490855395694e-17 2308/818/2118/3725/815/5684/2674/3562/4893/6464/1437/3667/2309/5604/2904/3561/5567/10048/817/1439/57690/5594/5568/3315/27327/3568/2064/1438/192670/4684/7316/10213/1950/3560/2263/983/5597/3718/2668/6714/5605/4609/5566/2261/5688/5159/3567/5687/3558/3717/5685/2244/5683/5708/5686/2335/2534/408/1445/816/192669/1847/3563/5979/23112/6654/6233/5527/2885/3716/8660/7514/7311/8826/7450/1956/60/5536/1843/4343/3570/3845/3265/3559/26523/5781/8202/3569/5245/7314/3572/5595 92 Human_T.cell_leukemia_virus_1 R-HSA-166166 MyD88-independent TLR4 cascade 47/1332 99/10654 1.104248473949952e-17 1.298265962830878e-16 5.659748695798575e-17 3665/3725/5601/351/9252/4790/6885/5604/7321/5594/841/7099/8517/7316/79155/5970/4792/4205/9261/3146/5598/1432/4208/466/5602/6195/2002/3661/7189/6285/5609/6233/1385/2353/6196/7311/7187/1386/6197/5599/5600/7334/3551/6416/5781/7314/5595 47 Human_T.cell_leukemia_virus_1 R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 47/1332 99/10654 1.104248473949952e-17 1.298265962830878e-16 5.659748695798575e-17 3665/3725/5601/351/9252/4790/6885/5604/7321/5594/841/7099/8517/7316/79155/5970/4792/4205/9261/3146/5598/1432/4208/466/5602/6195/2002/3661/7189/6285/5609/6233/1385/2353/6196/7311/7187/1386/6197/5599/5600/7334/3551/6416/5781/7314/5595 47 Human_T.cell_leukemia_virus_1 R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 20/1332 21/10654 1.4231794816673828e-17 1.6281302209980058e-16 7.097781316542223e-17 6118/2237/328/57804/5982/54107/3978/5425/5111/5426/6119/5427/5985/5984/5983/6117/5981/10714/5424/56655 20 Human_T.cell_leukemia_virus_1 R-HSA-167161 HIV Transcription Initiation 31/1332 47/10654 1.488354335570514e-17 1.6281302209980058e-16 7.097781316542223e-17 2963/5434/5440/902/2959/5430/6874/5436/404672/5441/5438/5431/5435/5433/6872/2960/4331/2966/2962/5437/2965/2068/5439/2071/2968/2967/6908/2961/1022/5432/2957 31 Human_T.cell_leukemia_virus_1 R-HSA-167162 RNA Polymerase II HIV Promoter Escape 31/1332 47/10654 1.488354335570514e-17 1.6281302209980058e-16 7.097781316542223e-17 2963/5434/5440/902/2959/5430/6874/5436/404672/5441/5438/5431/5435/5433/6872/2960/4331/2966/2962/5437/2965/2068/5439/2071/2968/2967/6908/2961/1022/5432/2957 31 Human_T.cell_leukemia_virus_1 R-HSA-73762 RNA Polymerase I Transcription Initiation 31/1332 47/10654 1.488354335570514e-17 1.6281302209980058e-16 7.097781316542223e-17 5434/5440/902/9112/9219/404672/5931/5441/5435/4331/1108/2966/8850/5928/5437/57459/2965/54815/2068/3066/3065/2071/1107/2968/57504/84172/2967/6908/53615/1022/10919 31 Human_T.cell_leukemia_virus_1 R-HSA-73776 RNA Polymerase II Promoter Escape 31/1332 47/10654 1.488354335570514e-17 1.6281302209980058e-16 7.097781316542223e-17 2963/5434/5440/902/2959/5430/6874/5436/404672/5441/5438/5431/5435/5433/6872/2960/4331/2966/2962/5437/2965/2068/5439/2071/2968/2967/6908/2961/1022/5432/2957 31 Human_T.cell_leukemia_virus_1 R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 31/1332 47/10654 1.488354335570514e-17 1.6281302209980058e-16 7.097781316542223e-17 2963/5434/5440/902/2959/5430/6874/5436/404672/5441/5438/5431/5435/5433/6872/2960/4331/2966/2962/5437/2965/2068/5439/2071/2968/2967/6908/2961/1022/5432/2957 31 Human_T.cell_leukemia_virus_1 R-HSA-75953 RNA Polymerase II Transcription Initiation 31/1332 47/10654 1.488354335570514e-17 1.6281302209980058e-16 7.097781316542223e-17 2963/5434/5440/902/2959/5430/6874/5436/404672/5441/5438/5431/5435/5433/6872/2960/4331/2966/2962/5437/2965/2068/5439/2071/2968/2967/6908/2961/1022/5432/2957 31 Human_T.cell_leukemia_virus_1 R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 31/1332 47/10654 1.488354335570514e-17 1.6281302209980058e-16 7.097781316542223e-17 2963/5434/5440/902/2959/5430/6874/5436/404672/5441/5438/5431/5435/5433/6872/2960/4331/2966/2962/5437/2965/2068/5439/2071/2968/2967/6908/2961/1022/5432/2957 31 Human_T.cell_leukemia_virus_1 R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 21/1332 23/10654 1.866108423010043e-17 2.0237624104712362e-16 8.822527117860548e-17 2963/5434/5440/5430/5436/5441/5438/5431/7469/5435/5433/9150/2962/5437/5439/6827/7936/6829/51497/5432/25920 21 Human_T.cell_leukemia_virus_1 R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 45/1332 93/10654 2.1636932200899274e-17 2.3067170092145156e-16 1.0056058587572276e-16 54106/3665/3725/5601/351/9252/4790/6885/5604/5594/4214/7099/8517/7316/79155/5970/4792/4205/9261/3146/5598/1432/4208/466/5602/6195/57162/2002/7189/6285/5609/6233/1385/2353/6196/7311/1386/6197/5599/5600/7334/3551/6416/7314/5595 45 Human_T.cell_leukemia_virus_1 R-HSA-975155 MyD88 dependent cascade initiated on endosome 45/1332 93/10654 2.1636932200899274e-17 2.3067170092145156e-16 1.0056058587572276e-16 54106/3665/3725/5601/351/9252/4790/6885/5604/5594/4214/7099/8517/7316/79155/5970/4792/4205/9261/3146/5598/1432/4208/466/5602/6195/57162/2002/7189/6285/5609/6233/1385/2353/6196/7311/1386/6197/5599/5600/7334/3551/6416/7314/5595 45 Human_T.cell_leukemia_virus_1 R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 45/1332 94/10654 3.657733326082778e-17 3.8667466590017936e-16 1.6856957654923727e-16 3665/3725/5601/351/9252/4790/6885/5604/7321/5594/841/8517/7316/79155/5970/4792/4205/9261/3146/5598/1432/4208/466/5602/6195/2002/3661/7189/6285/5609/6233/1385/2353/6196/7311/7187/1386/6197/5599/5600/7334/3551/6416/7314/5595 45 Human_T.cell_leukemia_virus_1 R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 49/1332 110/10654 5.984641883093702e-17 6.263619623470043e-16 2.7306048228833507e-16 1017/3725/1019/11065/4790/246184/1029/7321/8697/5594/1027/1051/79813/3576/3490/8881/7316/890/6774/5970/1026/51433/1031/5598/3552/1021/119504/6195/8900/51529/7324/64682/29945/10393/6233/51434/1032/2353/51343/6196/7311/25906/6197/29882/3569/10919/7314/996/5595 49 Human_T.cell_leukemia_virus_1 R-HSA-8953750 Transcriptional Regulation by E2F6 26/1332 35/10654 6.098093425599623e-17 6.263619623470043e-16 2.7306048228833507e-16 23468/5888/83746/7027/23269/2146/6045/84108/80012/5931/79813/4149/11335/1869/1876/1911/5928/10138/23512/1111/672/5932/8726/648/10919/6015 26 Human_T.cell_leukemia_virus_1 R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 45/1332 95/10654 6.124206786063714e-17 6.263619623470043e-16 2.7306048228833507e-16 3725/5601/351/9252/4790/6885/5604/5594/4214/7099/8517/7316/79155/5970/4792/4205/9261/8651/3146/5598/1432/4208/466/5602/6195/57162/2002/695/7189/6285/5609/6233/1385/2353/6196/7311/1386/6197/5599/5600/7334/3551/6416/7314/5595 45 Human_T.cell_leukemia_virus_1 R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 45/1332 95/10654 6.124206786063714e-17 6.263619623470043e-16 2.7306048228833507e-16 3725/5601/351/9252/4790/6885/5604/5594/4214/7099/8517/7316/79155/5970/4792/4205/9261/8651/3146/5598/1432/4208/466/5602/6195/57162/2002/695/7189/6285/5609/6233/1385/2353/6196/7311/1386/6197/5599/5600/7334/3551/6416/7314/5595 45 Human_T.cell_leukemia_virus_1 R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 44/1332 92/10654 8.618222375988267e-17 8.743325604026806e-16 3.811624667139124e-16 54106/3725/5601/351/9252/4790/6885/5604/5594/4214/7099/8517/7316/79155/5970/4792/4205/9261/3146/5598/1432/4208/466/5602/6195/57162/2002/7189/6285/5609/6233/1385/2353/6196/7311/1386/6197/5599/5600/7334/3551/6416/7314/5595 44 Human_T.cell_leukemia_virus_1 R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 42/1332 85/10654 9.661580660267738e-17 9.57029013434395e-16 4.172137193534597e-16 3725/5601/351/9252/4790/6885/5604/5594/4214/8517/7316/79155/5970/4792/4205/9261/3146/5598/1432/4208/466/5602/6195/57162/2002/7189/6285/5609/6233/1385/2353/6196/7311/1386/6197/5599/5600/7334/3551/6416/7314/5595 42 Human_T.cell_leukemia_virus_1 R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 42/1332 85/10654 9.661580660267738e-17 9.57029013434395e-16 4.172137193534597e-16 3725/5601/351/9252/4790/6885/5604/5594/4214/8517/7316/79155/5970/4792/4205/9261/3146/5598/1432/4208/466/5602/6195/57162/2002/7189/6285/5609/6233/1385/2353/6196/7311/1386/6197/5599/5600/7334/3551/6416/7314/5595 42 Human_T.cell_leukemia_virus_1 R-HSA-975871 MyD88 cascade initiated on plasma membrane 42/1332 85/10654 9.661580660267738e-17 9.57029013434395e-16 4.172137193534597e-16 3725/5601/351/9252/4790/6885/5604/5594/4214/8517/7316/79155/5970/4792/4205/9261/3146/5598/1432/4208/466/5602/6195/57162/2002/7189/6285/5609/6233/1385/2353/6196/7311/1386/6197/5599/5600/7334/3551/6416/7314/5595 42 Human_T.cell_leukemia_virus_1 R-HSA-110373 Resolution of AP sites via the multiple-nucleotide patch replacement pathway 22/1332 26/10654 1.05771335833324e-16 1.0395339099868874e-15 4.531814635621859e-16 6118/2237/328/57804/5982/54107/3978/5425/5111/5426/6119/5427/5985/142/5984/5983/6117/5981/10038/10714/5424/56655 22 Human_T.cell_leukemia_virus_1 R-HSA-162906 HIV Infection 77/1332 233/10654 1.1998197475450305e-16 1.1700567770632932e-15 5.100824875324039e-16 5905/2963/2237/6917/5434/5440/164/5684/902/162/3159/2959/5430/6874/5436/7518/7520/404672/6749/5441/5438/3978/3981/5431/7469/919/5435/7316/10213/5433/6872/2960/567/4331/926/2966/9150/2962/5688/5437/8812/5687/5685/5683/5708/2965/5686/2534/905/2068/5439/2071/6827/6233/2968/7514/1025/7311/2967/3932/6908/7251/11198/904/7936/6829/51497/2547/2961/1022/5432/1234/8178/2957/940/7314/25920 77 Human_T.cell_leukemia_virus_1 R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 45/1332 97/10654 1.6698855743331704e-16 1.6159354250085601e-15 7.044618495769894e-16 54106/3665/3725/5601/351/9252/4790/6885/5604/5594/4214/7099/8517/7316/79155/5970/4792/4205/9261/3146/5598/1432/4208/466/5602/6195/57162/2002/7189/6285/5609/6233/1385/2353/6196/7311/1386/6197/5599/5600/7334/3551/6416/7314/5595 45 Human_T.cell_leukemia_virus_1 R-HSA-2559580 Oxidative Stress Induced Senescence 52/1332 125/10654 2.368942009986115e-16 2.2749076706584217e-15 9.917386799540105e-16 1912/3725/1019/5601/1029/7027/2146/8535/6045/57690/5594/27327/80012/5931/50488/192670/7316/1869/9261/1911/4194/1031/5928/1432/84733/5602/23512/1021/57332/192669/7157/23135/23112/5609/6233/1032/2353/7311/4343/8726/5599/648/5600/23466/4217/26523/3456/6416/7314/6015/5595/4193 52 Human_T.cell_leukemia_virus_1 R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 45/1332 98/10654 2.720947729443051e-16 2.573648303488239e-15 1.1219736976967388e-15 3725/5601/351/9252/4790/6885/5604/5594/4214/7099/8517/7316/79155/5970/4792/4205/9261/8651/3146/5598/1432/4208/466/5602/6195/57162/2002/695/7189/6285/5609/6233/1385/2353/6196/7311/1386/6197/5599/5600/7334/3551/6416/7314/5595 45 Human_T.cell_leukemia_virus_1 R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 45/1332 98/10654 2.720947729443051e-16 2.573648303488239e-15 1.1219736976967388e-15 3725/5601/351/9252/4790/6885/5604/5594/4214/7099/8517/7316/79155/5970/4792/4205/9261/8651/3146/5598/1432/4208/466/5602/6195/57162/2002/695/7189/6285/5609/6233/1385/2353/6196/7311/1386/6197/5599/5600/7334/3551/6416/7314/5595 45 Human_T.cell_leukemia_virus_1 R-HSA-187037 Signaling by NTRK1 (TRKA) 40/1332 80/10654 3.088131164074207e-16 2.8991559734368302e-15 1.2638777191537015e-15 5295/9252/4893/6464/5290/3667/5335/4915/5291/5604/135/5594/6774/4205/9261/6714/5605/5598/1432/4208/466/4914/6195/4803/5603/2002/6654/2885/8660/1385/6196/387/5296/6197/3845/5600/3265/1399/6300/5595 40 Human_T.cell_leukemia_virus_1 R-HSA-400253 Circadian Clock 37/1332 70/10654 3.8548889353633676e-16 3.592185393101567e-15 1.566001664970226e-15 5187/8841/1374/8204/3091/200186/4783/6720/5465/406/4209/7316/9611/5469/5501/64784/4208/1387/150094/2908/6604/1390/2033/79365/5499/10498/6233/1385/7311/23054/1386/23411/1453/23373/8648/10891/7314 37 Human_T.cell_leukemia_virus_1 R-HSA-69206 G1/S Transition 53/1332 131/10654 5.107466671069239e-16 4.724406670739046e-15 2.0595898882562486e-15 1017/4172/6118/1019/5684/902/8318/23594/7027/207/1027/54107/5925/4149/7316/10213/1869/891/993/890/1876/4331/983/1026/5111/5426/4171/4609/51053/6119/5928/5688/5687/5427/6502/5685/5683/5708/10000/5686/990/595/81620/3065/8900/208/6233/7311/6117/7465/1022/7314/56655 53 Human_T.cell_leukemia_virus_1 R-HSA-450294 MAP kinase activation 35/1332 64/10654 5.947470019820332e-16 5.461253492652538e-15 2.380815889609215e-15 3725/5601/9252/4790/6885/5604/5594/8517/7316/79155/4205/9261/5598/1432/4208/466/5602/6195/2002/7189/5609/6233/1385/2353/6196/7311/1386/6197/5599/5600/7334/3551/6416/7314/5595 35 Human_T.cell_leukemia_virus_1 R-HSA-2871796 FCERI mediated MAPK activation 24/1332 32/10654 6.822455771157839e-16 6.174567884975944e-15 2.6917830039933618e-15 3725/5601/4893/6464/2205/5335/3937/5594/4214/2206/6850/4067/5602/5609/6654/2885/7409/2353/3845/5599/3265/6416/2207/5595 24 Human_T.cell_leukemia_virus_1 R-HSA-5656169 Termination of translesion DNA synthesis 24/1332 32/10654 6.822455771157839e-16 6.174567884975944e-15 2.6917830039933618e-15 6118/57804/5982/54107/7706/7316/5425/5111/5426/6119/5427/5429/5985/5984/6233/51426/7311/5983/6117/5981/10714/5424/7314/56655 24 Human_T.cell_leukemia_virus_1 R-HSA-1433557 Signaling by SCF-KIT 28/1332 43/10654 9.25740915611101e-16 8.318443370276892e-15 3.626398624311155e-15 5295/5777/4893/5290/5578/4318/6776/6774/6772/6714/8651/8503/867/4067/3717/2534/1111/6654/2885/7409/9846/3932/5296/3845/10076/6777/3265/5781 28 Human_T.cell_leukemia_virus_1 R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 52/1332 129/10654 1.1623179405393127e-15 1.0370184178712449e-14 4.520848428674744e-15 3665/3725/5601/351/9252/4790/6885/5604/7321/3684/5594/4214/841/7099/8517/7316/79155/5970/4792/4205/9261/8651/3146/5598/1432/4208/466/5602/6195/57162/2002/3661/695/7189/6285/5609/6233/1385/2353/6196/7311/7187/1386/6197/5599/5600/7334/3551/6416/5781/7314/5595 52 Human_T.cell_leukemia_virus_1 R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 28/1332 44/10654 2.2445081064842653e-15 1.988444505603666e-14 8.668559847874739e-15 7027/7321/6497/51592/3726/54778/7316/9611/9612/1024/6667/4092/4609/4089/22938/8812/7050/4088/142/905/3065/4087/6233/1025/7311/904/7314/4221 28 Human_T.cell_leukemia_virus_1 R-HSA-5693606 DNA Double Strand Break Response 38/1332 77/10654 2.9893127053564515e-15 2.6297590093275633e-14 1.1464349793821946e-14 8467/25/3838/322/10111/51588/51720/11200/472/7336/580/29086/7316/2140/2070/9031/9656/7341/10524/4683/165918/7157/9682/7329/8924/6233/672/7158/7311/2138/9025/79184/23030/5536/5599/7334/2139/7314 38 Human_T.cell_leukemia_virus_1 R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 20/1332 24/10654 4.9502278019152766e-15 4.324574010284318e-14 1.8852841263142247e-14 6118/2237/1763/57804/5982/54107/3978/5425/5111/5426/6119/5427/5985/5984/5983/6117/5981/10714/5424/56655 20 Human_T.cell_leukemia_virus_1 R-HSA-168898 Toll-like Receptor Cascades 57/1332 155/10654 6.244702023215206e-15 5.417817341520502e-14 2.361880039270506e-14 54106/3665/3725/5601/351/9252/4790/6885/5604/7184/7321/3684/5594/4214/841/7099/8517/338/7316/79155/5970/4792/4205/9261/8651/3146/5598/1432/4208/466/2244/5602/6195/57162/2002/3661/695/7189/6285/5609/6233/1385/81622/2353/6196/7311/7187/1386/6197/5599/5600/7334/3551/6416/5781/7314/5595 57 Human_T.cell_leukemia_virus_1 R-HSA-71291 Metabolism of amino acids and derivatives 101/1332 372/10654 6.972893235042183e-15 6.008150472385662e-14 2.6192338683900345e-14 6158/6138/6144/6203/5684/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/9521/6129/3620/5160/6217/9255/6222/6176/383/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/4552/6232/6134/6169/6160/6164/6155/10213/6175/6218/5092/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/5688/6228/23521/5687/116832/5685/5683/5708/8604/5686/5162/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 101 Human_T.cell_leukemia_virus_1 R-HSA-9614085 FOXO-mediated transcription 34/1332 65/10654 9.25562952572542e-15 7.920804043103794e-14 3.4530490389566373e-14 2308/2309/10018/356/207/23410/1027/4287/6720/1649/4800/5443/1026/4089/8850/1647/1387/4088/2908/10000/6794/2033/4852/4801/3630/3066/3065/6648/4087/208/604/23411/2538/10891 34 Human_T.cell_leukemia_virus_1 R-HSA-448424 Interleukin-17 signaling 36/1332 72/10654 9.551668975771256e-15 8.118918629405568e-14 3.539416455460046e-14 3605/3725/5601/9252/4790/6885/5604/5594/8517/7316/79155/4205/9261/5598/1432/4208/466/5602/6195/2002/7189/5609/6233/1385/2353/6196/7311/1386/6197/5599/5600/7334/3551/6416/7314/5595 36 Human_T.cell_leukemia_virus_1 R-HSA-162599 Late Phase of HIV Life Cycle 53/1332 139/10654 9.8563888502851545e-015 8.321702801113237e-14 3.62781956269768e-14 5905/2963/6917/5434/5440/902/2959/5430/6874/5436/404672/6749/5441/5438/5431/7469/5435/7316/5433/6872/2960/4331/2966/9150/2962/5437/8812/2965/905/2068/5439/2071/6827/6233/2968/7514/1025/7311/2967/6908/7251/11198/904/7936/6829/51497/2961/1022/5432/8178/2957/7314/25920 53 Human_T.cell_leukemia_virus_1 R-HSA-8986944 Transcriptional Regulation by MECP2 33/1332 62/10654 1.1766800167735102e-14 9.868423074007172e-14 4.302107289396483e-14 818/627/815/8841/5468/2904/6446/817/9212/57690/27327/6657/192670/9611/2874/9612/5566/4988/4208/3064/5728/1392/816/192669/3066/3065/4204/23112/1385/4343/26523/2891/814 33 Human_T.cell_leukemia_virus_1 R-HSA-5693565 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 37/1332 76/10654 1.2102249793021276e-14 1.0082536582530308e-13 4.395449384568899e-14 8467/25/322/10111/51588/51720/11200/472/7336/580/29086/7316/2140/2070/9031/9656/7341/10524/4683/165918/7157/9682/7329/8924/6233/672/7158/7311/2138/9025/79184/23030/5536/5599/7334/2139/7314 37 Human_T.cell_leukemia_virus_1 R-HSA-170834 Signaling by TGF-beta Receptor Complex 36/1332 73/10654 1.6608854507497583e-14 1.3746012480547344e-13 5.992529915793795e-14 5590/7027/7321/6497/51592/3726/54778/7316/9611/5501/9612/1024/6667/4092/4609/4089/22938/867/8812/7050/4088/142/905/3065/9040/4087/5499/6233/7514/1025/7311/387/7040/904/7314/4221 36 Human_T.cell_leukemia_virus_1 R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 20/1332 25/10654 2.1845357009680547e-14 1.784510332349229e-13 7.779515380754317e-14 11065/246184/7321/8697/8881/7316/51433/119504/51529/7324/64682/29945/10393/6233/51434/7311/25906/29882/7314/996 20 Human_T.cell_leukemia_virus_1 R-HSA-9006335 Signaling by Erythropoietin 20/1332 25/10654 2.1845357009680547e-14 1.784510332349229e-13 7.779515380754317e-14 5295/4893/6464/5290/5335/5291/6776/4067/3717/2057/6654/2885/2056/7409/8660/5293/3845/6777/3265/1399 20 Human_T.cell_leukemia_virus_1 R-HSA-180786 Extension of Telomeres 22/1332 30/10654 2.5088509377592653e-14 2.036215793355584e-13 8.87681723988168e-14 6118/2237/7015/1763/57804/5982/54107/3978/5425/5111/5426/6119/1736/5427/5985/5984/5983/6117/5981/10714/5424/56655 22 Human_T.cell_leukemia_virus_1 R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 28/1332 47/10654 2.5742113755971272e-14 2.075870455449478e-13 9.049690463468983e-14 8841/9734/55869/51564/55534/84441/3091/10013/10046/7316/9611/9612/1024/4609/10014/22938/8850/1387/2033/55294/3066/3065/9794/6233/7311/3516/4851/7314 28 Human_T.cell_leukemia_virus_1 R-HSA-5358508 Mismatch Repair 15/1332 15/10654 2.6594710485252445e-14 2.1309647000285082e-13 9.289872050161934e-14 6118/4436/9156/57804/2956/4292/3978/5425/5111/5395/6119/6117/10714/5424/4437 15 Human_T.cell_leukemia_virus_1 R-HSA-9022692 Regulation of MECP2 expression and activity 23/1332 33/10654 3.799023348294056e-14 3.024792007692356e-13 1.3186483440780835e-13 818/815/8841/817/9212/57690/27327/192670/9611/2874/9612/5566/3064/816/192669/3066/3065/4204/23112/1385/4343/26523/814 23 Human_T.cell_leukemia_virus_1 R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 17/1332 19/10654 5.433141984972394e-14 4.245274917450479e-13 1.8507139419226002e-13 5295/4893/6464/5290/5335/7316/1950/867/3320/6654/6233/2885/7311/1956/3845/3265/7314 17 Human_T.cell_leukemia_virus_1 R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 17/1332 19/10654 5.433141984972394e-14 4.245274917450479e-13 1.8507139419226002e-13 11065/246184/7321/8697/8881/51433/119504/51529/7324/64682/29945/10393/51434/51343/25906/29882/996 17 Human_T.cell_leukemia_virus_1 R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 17/1332 19/10654 5.433141984972394e-14 4.245274917450479e-13 1.8507139419226002e-13 5295/4893/6464/5290/5335/7316/1950/867/3320/6654/6233/2885/7311/1956/3845/3265/7314 17 Human_T.cell_leukemia_virus_1 R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 25/1332 39/10654 5.6583325796074285e-14 4.366983058371868e-13 1.9037722143851923e-13 6118/57804/5982/54107/7706/7316/5425/5111/5426/7415/6119/5427/5429/5985/5984/6233/51426/7311/5983/6117/5981/10714/5424/7314/56655 25 Human_T.cell_leukemia_virus_1 R-HSA-73933 Resolution of Abasic Sites (AP sites) 25/1332 39/10654 5.6583325796074285e-14 4.366983058371868e-13 1.9037722143851923e-13 11284/6118/2237/328/57804/7515/5982/54107/3978/5425/5111/5426/6119/5427/5985/142/5984/3980/5983/6117/5981/10038/10714/5424/56655 25 Human_T.cell_leukemia_virus_1 R-HSA-877300 Interferon gamma signaling 40/1332 92/10654 1.1910767297198336e-13 9.136430036509457e-13 3.9829972797434753e-13 3135/3665/818/3460/5777/815/6737/960/3107/817/9021/85363/23650/3383/7706/3662/4684/3663/3664/567/6772/8651/3659/3106/3459/7341/3717/3458/816/3661/10346/5371/3716/3133/3134/5781/4261/3105/3660/8554 40 Human_T.cell_leukemia_virus_1 R-HSA-176187 Activation of ATR in response to replication stress 24/1332 37/10654 1.2335903352737798e-13 9.405191768329788e-13 4.100163092042356e-13 1017/4172/6118/8318/23594/5883/5982/63967/545/993/4171/6119/3364/144715/5985/990/995/84126/1111/5984/5983/6117/5884/5810 24 Human_T.cell_leukemia_virus_1 R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 36/1332 77/10654 1.3391356579453244e-13 1.0148389504188062e-12 4.424157753896728e-13 1912/5893/1029/7486/8535/51564/6045/51588/7518/80012/10274/6613/10735/5885/1911/641/23137/9656/7341/84733/165918/8243/9126/57332/142/1069/7329/5371/8924/672/9063/6117/648/7508/6015/8554 36 Human_T.cell_leukemia_virus_1 R-HSA-9607240 FLT3 Signaling 78/1332 267/10654 1.495246416283431e-13 1.126359276457818e-12 4.9103270273159e-13 5295/54106/818/815/5684/2674/3562/4893/6464/5290/1437/3667/5291/5604/2904/3561/10048/817/1439/5594/3568/2064/1438/6776/4684/7316/10213/1950/3560/2263/3718/2668/6714/5605/2261/5688/5159/3567/5687/3558/3717/5685/2244/5683/5708/5686/2335/2534/408/1445/816/1847/3563/5979/208/6654/6233/5527/2885/3716/8660/7311/8826/9846/7450/1956/60/5536/5296/1843/3845/6777/3265/3559/5781/5245/7314/5595 78 Human_T.cell_leukemia_virus_1 R-HSA-2219528 PI3K/AKT Signaling in Cancer 42/1332 101/10654 1.8626799592725842e-13 1.394792493312447e-12 6.080552999881056e-13 5295/2308/5290/3667/2309/5291/842/207/1027/930/941/2064/6199/2100/1950/2263/1026/6714/2099/8503/2932/2261/5159/3164/10000/2534/5728/942/208/2885/2475/7409/8660/1385/3932/2931/5293/1956/5296/5781/940/4193 42 Human_T.cell_leukemia_virus_1 R-HSA-913531 Interferon Signaling 64/1332 199/10654 2.0015635684152582e-13 1.4899212834712396e-12 6.495263899995949e-13 3135/3665/818/3460/5777/815/3838/6737/5335/960/3455/3107/817/9021/85363/23650/3383/25820/1982/7706/3662/4684/7316/3663/3664/567/4734/6772/8651/3659/3106/8672/3459/1958/7341/3717/1981/1973/3458/3454/816/3661/10346/7324/1977/5371/3439/6233/3716/7311/3133/5610/3134/5300/7334/3456/5781/4261/3105/3660/1974/7314/5595/8554 64 Human_T.cell_leukemia_virus_1 R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 14/1332 14/10654 2.1469477963815358e-13 1.5745150916577727e-12 6.864047885145174e-13 6118/4436/9156/57804/2956/4292/3978/5425/5111/5395/6119/6117/10714/5424 14 Human_T.cell_leukemia_virus_1 R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 14/1332 14/10654 2.1469477963815358e-13 1.5745150916577727e-12 6.864047885145174e-13 6118/4436/9156/57804/4292/3978/5425/5111/5395/6119/6117/10714/5424/4437 14 Human_T.cell_leukemia_virus_1 R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 22/1332 32/10654 2.152755133268179e-13 1.5745150916577727e-12 6.864047885145174e-13 7027/3726/54778/7316/1024/6667/4092/4609/4089/22938/8812/7050/4088/905/3065/4087/6233/1025/7311/904/7314/4221 22 Human_T.cell_leukemia_virus_1 R-HSA-6783783 Interleukin-10 signaling 27/1332 47/10654 2.5926114646157893e-13 1.885263134385354e-12 8.218743979706883e-13 729230/7124/1437/3587/6351/3553/2919/5743/941/3383/3576/2920/6352/6774/6348/1440/3627/7133/3606/3552/942/3716/6347/3588/3569/1234/3586 27 Human_T.cell_leukemia_virus_1 R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 24/1332 38/10654 2.9535035902891746e-13 2.1353491474619434e-12 9.308985907686993e-13 1912/6597/8535/6045/80012/6598/6599/865/1457/1911/51412/84733/6604/8289/10138/2033/6605/6602/57332/861/648/6601/23466/6015 24 Human_T.cell_leukemia_virus_1 R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 21/1332 30/10654 4.396509615503492e-13 3.160462340744796e-12 1.3777933892795907e-12 6118/57804/5982/54107/7316/5425/5111/5426/6119/5427/5985/5984/6233/7311/5983/6117/5981/10714/5424/7314/56655 21 Human_T.cell_leukemia_virus_1 R-HSA-3899300 SUMOylation of transcription cofactors 26/1332 45/10654 5.988635123265135e-13 4.280513059697466e-12 1.8660758966633587e-12 1912/1487/8204/8535/6045/51588/80012/6613/9612/1911/7341/1387/84733/1616/2033/57332/7329/10155/9063/7690/648/11315/8648/10891/6015/8554 26 Human_T.cell_leukemia_virus_1 R-HSA-8878159 Transcriptional regulation by RUNX3 40/1332 96/10654 6.497800886982708e-13 4.618211025889405e-12 2.01329423854772e-12 5684/2309/1499/10018/1029/55534/84441/10046/7316/10213/865/1026/10413/6714/6934/4609/4089/22938/8850/5688/1387/5687/4088/5685/5683/5708/5686/2033/595/7157/861/9794/6233/7311/7040/3845/3516/4851/7314/4193 40 Human_T.cell_leukemia_virus_1 R-HSA-8878166 Transcriptional regulation by RUNX2 46/1332 121/10654 6.579446317891532e-13 4.6499682403974986e-12 2.0271386940399103e-12 8493/25/1019/5684/8841/6662/207/5594/5925/10013/7316/10213/891/865/4094/983/1026/10413/6772/6714/2099/4089/2736/2932/5688/5687/6502/2908/5685/5683/5708/10000/5686/2101/595/55294/23314/861/208/6233/7311/367/860/10891/7314/5595 46 Human_T.cell_leukemia_virus_1 R-HSA-5654738 Signaling by FGFR2 34/1332 73/10654 7.366462863751356e-13 5.17710071653587e-12 2.2569404010670134e-12 5295/2963/5434/5440/4893/6464/5290/5335/5430/5436/5594/5441/5438/5431/5435/7316/5433/2263/6714/2962/867/5437/4670/5439/6654/6233/2885/7311/3845/3265/5781/5432/7314/5595 34 Human_T.cell_leukemia_virus_1 R-HSA-350054 Notch-HLH transcription pathway 20/1332 28/10654 8.787931928404362e-13 6.141787981073716e-12 2.677492710350101e-12 8841/9734/55869/51564/55534/84441/10013/10046/9611/9612/10014/22938/8850/1387/4853/3066/3065/9794/3516/4851 20 Human_T.cell_leukemia_virus_1 R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 21/1332 31/10654 1.2028025283686996e-12 8.335981899038691e-12 3.6340444894980825e-12 3725/5601/9252/5594/4205/9261/5598/1432/4208/466/5602/6195/2002/1385/2353/6196/1386/6197/5599/5600/5595 21 Human_T.cell_leukemia_virus_1 R-HSA-1226099 Signaling by FGFR in disease 31/1332 63/10654 1.206000560910208e-12 8.335981899038691e-12 3.6340444894980825e-12 5295/2963/5434/5440/4893/5290/5335/5430/5436/5441/5438/5431/6776/5435/5433/6774/2263/6772/2962/2261/5437/11064/5439/6654/2885/9846/3845/6777/3265/5432/7750 31 Human_T.cell_leukemia_virus_1 R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 37/1332 86/10654 1.4743465598293302e-12 1.008004332752879e-11 4.394362458072546e-12 1017/5684/11065/246184/7321/8697/9212/8881/7316/10213/891/890/983/51433/5688/5687/6502/5685/5683/5708/5686/119504/8900/51529/7324/64682/29945/10393/6233/51434/51343/7311/25906/5347/29882/7314/996 37 Human_T.cell_leukemia_virus_1 R-HSA-453276 Regulation of mitotic cell cycle 37/1332 86/10654 1.4743465598293302e-12 1.008004332752879e-11 4.394362458072546e-12 1017/5684/11065/246184/7321/8697/9212/8881/7316/10213/891/890/983/51433/5688/5687/6502/5685/5683/5708/5686/119504/8900/51529/7324/64682/29945/10393/6233/51434/51343/7311/25906/5347/29882/7314/996 37 Human_T.cell_leukemia_virus_1 R-HSA-69052 Switching of origins to a post-replicative state 38/1332 90/10654 1.4967325656906207e-12 1.017778144669622e-11 4.436971076670347e-12 1017/4172/5684/11065/246184/23594/7321/8697/8881/7316/10213/890/4171/51433/5688/5687/6502/5685/5683/5708/5686/990/119504/81620/8900/51529/7324/64682/29945/10393/6233/51434/51343/7311/25906/29882/7314/996 38 Human_T.cell_leukemia_virus_1 R-HSA-6806003 Regulation of TP53 Expression and Degradation 23/1332 37/10654 1.5183413886456758e-12 1.026921218772183e-11 4.4768300140599726e-12 1017/1029/6446/207/11200/472/639/7316/890/983/4194/1616/10000/7157/8900/208/6233/5527/2475/7311/7874/7314/4193 23 Human_T.cell_leukemia_virus_1 R-HSA-5684996 MAPK1/MAPK3 signaling 73/1332 255/10654 2.7598110981722705e-12 1.856600193315891e-11 8.093788810288506e-12 818/815/5684/2674/3562/4893/6464/1437/3667/5604/2904/3561/10048/817/1439/5594/3568/2064/1438/4684/7316/10213/1950/3560/2263/983/3718/2668/6714/5605/2261/5688/5159/3567/5687/3558/3717/5685/2244/5683/5708/5686/2335/2534/408/1445/816/1847/3563/5979/6654/6233/5527/2885/3716/8660/7311/8826/7450/1956/60/5536/1843/3570/3845/3265/3559/5781/3569/5245/7314/3572/5595 73 Human_T.cell_leukemia_virus_1 R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 33/1332 72/10654 2.8101836408537837e-12 1.8804313937202446e-11 8.197680161729124e-12 1017/5684/11065/246184/7321/8697/8881/7316/10213/890/51433/5688/5687/5685/5683/5708/5686/990/119504/8900/51529/7324/64682/29945/10393/6233/51434/51343/7311/25906/29882/7314/996 33 Human_T.cell_leukemia_virus_1 R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 35/1332 80/10654 3.2881288550094787e-12 2.18860640190578e-11 9.541159194987128e-12 1017/5684/11065/246184/7321/8697/8881/7316/10213/891/890/983/51433/5688/5687/5685/5683/5708/5686/119504/8900/51529/7324/64682/29945/10393/6233/51434/51343/7311/25906/5347/29882/7314/996 35 Human_T.cell_leukemia_virus_1 R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 36/1332 85/10654 5.203741125239281e-12 3.445424387132113e-11 1.5020216765926123e-11 1017/1019/5684/994/902/7027/207/1027/5925/4149/7316/10213/1869/993/890/4331/1026/4609/5928/5688/5687/6502/5685/5683/5708/10000/5686/595/8900/208/6233/51343/7311/7465/1022/7314 36 Human_T.cell_leukemia_virus_1 R-HSA-912631 Regulation of signaling by CBL 17/1332 22/10654 5.76741473964079e-12 3.798642797103724e-11 1.6560061060087364e-11 5295/5290/5291/7316/6850/8503/867/4067/2534/6233/2885/7409/7311/5293/5296/1399/7314 17 Human_T.cell_leukemia_virus_1 R-HSA-2424491 DAP12 signaling 20/1332 30/10654 6.619317307494108e-12 4.337031860847702e-11 1.8907150861866395e-11 5295/4893/6464/5290/5335/5291/3937/3824/567/6850/2534/22914/695/6654/2885/3133/3932/5296/3845/3265 20 Human_T.cell_leukemia_virus_1 R-HSA-6804757 Regulation of TP53 Degradation 22/1332 36/10654 7.67974849640609e-12 5.005763527709255e-11 2.1822465048418726e-11 1017/1029/6446/207/11200/472/7316/890/983/4194/1616/10000/7157/8900/208/6233/5527/2475/7311/7874/7314/4193 22 Human_T.cell_leukemia_virus_1 R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 16/1332 20/10654 9.724449926396057e-12 6.241509187452163e-11 2.72096584943735e-11 11065/246184/7321/8697/8881/51433/119504/51529/7324/64682/29945/10393/51434/25906/29882/996 16 Human_T.cell_leukemia_virus_1 R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 16/1332 20/10654 9.724449926396057e-12 6.241509187452163e-11 2.72096584943735e-11 11065/246184/7321/8697/8881/51433/119504/51529/7324/64682/29945/10393/51434/25906/29882/996 16 Human_T.cell_leukemia_virus_1 R-HSA-69186 Lagging Strand Synthesis 16/1332 20/10654 9.724449926396057e-12 6.241509187452163e-11 2.72096584943735e-11 6118/2237/1763/57804/5982/3978/5425/5111/6119/5985/5984/5983/6117/5981/10714/5424 16 Human_T.cell_leukemia_virus_1 R-HSA-9020558 Interleukin-2 signaling 12/1332 12/10654 1.3963955482619525e-11 8.91708426250526e-11 3.88737419526838e-11 6464/3561/6776/3560/6850/3718/3558/3716/3932/2185/6777/3559 12 Human_T.cell_leukemia_virus_1 R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 15/1332 18/10654 1.4991242541194155e-11 9.524738947890024e-11 4.152279300352023e-11 4893/5578/5594/4314/5598/6195/6654/2885/1385/6196/1956/6197/3845/3265/5595 15 Human_T.cell_leukemia_virus_1 R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 32/1332 72/10654 1.673502374485522e-11 1.0579226065843149e-10 4.611979566818075e-11 5684/11065/246184/7321/8697/9212/8881/7316/10213/51433/5688/5687/6502/5685/5683/5708/5686/119504/51529/7324/64682/29945/10393/6233/51434/51343/7311/25906/5347/29882/7314/996 32 Human_T.cell_leukemia_virus_1 R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 33/1332 76/10654 1.7640782849878548e-11 1.1096052412573607e-10 4.837288349887749e-11 5684/11065/246184/7321/8697/8881/7316/10213/891/890/983/51433/5688/5687/5685/5683/5708/5686/119504/8900/51529/7324/64682/29945/10393/6233/51434/7311/25906/5347/29882/7314/996 33 Human_T.cell_leukemia_virus_1 R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 14/1332 16/10654 2.015183464995865e-11 1.2612441785894519e-10 5.498353418501418e-11 5295/6464/5290/2205/5291/2206/6850/4067/2534/6654/2885/9846/5296/2207 14 Human_T.cell_leukemia_virus_1 R-HSA-9027284 Erythropoietin activates RAS 13/1332 14/10654 2.1457595690188828e-11 1.3363195731810667e-10 5.825642185819896e-11 4893/6464/4067/3717/2057/6654/2885/2056/7409/8660/3845/3265/1399 13 Human_T.cell_leukemia_virus_1 R-HSA-9009391 Extra-nuclear estrogen signaling 33/1332 77/10654 2.7214175995101494e-11 1.6864745518146638e-10 7.35213154962296e-11 5295/596/5590/4893/6464/5290/2309/207/5594/6722/1027/3315/4318/2100/1950/4314/6714/2099/8503/10000/3320/4846/595/2002/208/7514/1385/2353/1956/5296/3845/3265/5595 33 Human_T.cell_leukemia_virus_1 R-HSA-8853659 RET signaling 23/1332 41/10654 3.044981686400646e-11 1.8777387066137318e-10 8.185941478920209e-11 5295/2674/6464/5290/5335/5291/5567/5578/5568/2668/6714/5566/8503/5598/5979/6654/2885/8660/9846/5293/5296/5781/9046 23 Human_T.cell_leukemia_virus_1 R-HSA-186763 Downstream signal transduction 19/1332 29/10654 3.583741987841466e-11 2.199193863758324e-10 9.587314894302459e-11 5295/4893/5290/5335/5291/6778/6776/6774/6772/6714/5159/6654/2885/5296/3845/6777/3265/1399/5781 19 Human_T.cell_leukemia_virus_1 R-HSA-73893 DNA Damage Bypass 25/1332 48/10654 3.752233135160191e-11 2.2914122738017093e-10 9.989338085940009e-11 6118/57804/5982/54107/7706/7316/5425/5111/5426/7415/6119/5427/5429/5985/5984/6233/51426/7311/5983/6117/5981/10714/5424/7314/56655 25 Human_T.cell_leukemia_virus_1 R-HSA-3247509 Chromatin modifying enzymes 74/1332 274/10654 4.2503449492328946e-11 2.5706413202572027e-10 1.1206628130315478e-10 84678/9070/1810/1019/8841/11091/4790/84148/6597/23186/55869/2146/5978/1788/9112/9219/8085/5929/5931/6598/79813/6599/7403/54496/9611/2874/5970/11143/9612/29072/51412/1108/2122/8850/5928/10524/1387/57459/3717/6604/8289/54815/2033/23512/6605/6602/595/3066/3065/9682/1107/23028/23135/10498/9757/22992/57504/80854/58508/23030/57634/1386/51317/60/8726/6601/55729/6187/53615/8648/64754/4297/10919/79723 74 Human_T.cell_leukemia_virus_1 R-HSA-4839726 Chromatin organization 74/1332 274/10654 4.2503449492328946e-11 2.5706413202572027e-10 1.1206628130315478e-10 84678/9070/1810/1019/8841/11091/4790/84148/6597/23186/55869/2146/5978/1788/9112/9219/8085/5929/5931/6598/79813/6599/7403/54496/9611/2874/5970/11143/9612/29072/51412/1108/2122/8850/5928/10524/1387/57459/3717/6604/8289/54815/2033/23512/6605/6602/595/3066/3065/9682/1107/23028/23135/10498/9757/22992/57504/80854/58508/23030/57634/1386/51317/60/8726/6601/55729/6187/53615/8648/64754/4297/10919/79723 74 Human_T.cell_leukemia_virus_1 R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 29/1332 63/10654 5.196475878366633e-11 3.127830935399629e-10 1.3635678331045158e-10 5684/11065/246184/7321/8697/8881/7316/10213/51433/5688/5687/5685/5683/5708/5686/119504/51529/7324/64682/29945/10393/6233/51434/51343/7311/25906/29882/7314/996 29 Human_T.cell_leukemia_virus_1 R-HSA-190236 Signaling by FGFR 35/1332 87/10654 5.937124436921159e-11 3.5566202579270565e-10 1.550497158714749e-10 5295/2963/5434/5440/4893/6464/5290/5335/5430/5436/5594/5441/5438/5431/5435/7316/5433/2263/6714/2962/2261/867/5437/4670/5439/6654/6233/2885/7311/3845/3265/5781/5432/7314/5595 35 Human_T.cell_leukemia_virus_1 R-HSA-69202 Cyclin E associated events during G1/S transition 34/1332 83/10654 6.174702728383567e-11 3.6814104418514343e-10 1.6048990379086248e-10 1017/1019/5684/902/7027/207/1027/5925/4149/7316/10213/1869/993/890/4331/1026/4609/5928/5688/5687/6502/5685/5683/5708/10000/5686/595/8900/208/6233/7311/7465/1022/7314 34 Human_T.cell_leukemia_virus_1 R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 32/1332 75/10654 6.273960388598623e-11 3.7008258808584806e-10 1.6133631360783772e-10 5684/11065/246184/7321/8697/8881/7316/10213/891/890/983/51433/5688/5687/5685/5683/5708/5686/119504/8900/51529/7324/64682/29945/10393/6233/51434/7311/25906/29882/7314/996 32 Human_T.cell_leukemia_virus_1 R-HSA-110320 Translesion Synthesis by POLH 15/1332 19/10654 6.295522563622535e-11 3.7008258808584806e-10 1.6133631360783772e-10 6118/5982/7316/5111/7415/6119/5429/5985/5984/6233/7311/5983/6117/5981/7314 15 Human_T.cell_leukemia_virus_1 R-HSA-8851708 Signaling by FGFR2 IIIa TM 15/1332 19/10654 6.295522563622535e-11 3.7008258808584806e-10 1.6133631360783772e-10 2963/5434/5440/5430/5436/5441/5438/5431/5435/5433/2263/2962/5437/5439/5432 15 Human_T.cell_leukemia_virus_1 R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 31/1332 72/10654 9.427409701027769e-11 5.516130885531596e-10 2.4047395124775854e-10 5684/11065/246184/7321/8697/8881/7316/10213/890/983/51433/5688/5687/5685/5683/5708/5686/119504/8900/51529/7324/64682/29945/10393/6233/51434/7311/25906/29882/7314/996 31 Human_T.cell_leukemia_virus_1 R-HSA-5655862 Translesion synthesis by POLK 14/1332 17/10654 1.0100454960555977e-10 5.855471124598811e-10 2.5526737979382317e-10 6118/5982/7316/5111/6119/5985/5984/6233/51426/7311/5983/6117/5981/7314 14 Human_T.cell_leukemia_virus_1 R-HSA-8934593 Regulation of RUNX1 Expression and Activity 14/1332 17/10654 1.0100454960555977e-10 5.855471124598811e-10 2.5526737979382317e-10 57690/27327/192670/865/6714/1021/595/192669/861/5371/23112/4343/26523/5781 14 Human_T.cell_leukemia_virus_1 R-HSA-174414 Processive synthesis on the C-strand of the telomere 11/1332 11/10654 1.125044498118996e-10 6.472145423446164e-10 2.8215109744920525e-10 6118/2237/1763/57804/3978/5425/5111/6119/6117/10714/5424 11 Human_T.cell_leukemia_virus_1 R-HSA-5655253 Signaling by FGFR2 in disease 23/1332 43/10654 1.1267089409655883e-10 6.472145423446164e-10 2.8215109744920525e-10 5295/2963/5434/5440/4893/5290/5335/5430/5436/5441/5438/5431/5435/5433/2263/2962/5437/5439/6654/2885/3845/3265/5432 23 Human_T.cell_leukemia_virus_1 R-HSA-1227986 Signaling by ERBB2 25/1332 50/10654 1.1922606780700092e-10 6.817563331873052e-10 2.972094800356339e-10 5295/4893/6464/5290/5335/207/5578/2064/7316/1950/6714/10000/3320/2534/208/6654/6233/2885/7311/387/1956/5581/3845/3265/7314 25 Human_T.cell_leukemia_virus_1 R-HSA-5637810 Constitutive Signaling by EGFRvIII 13/1332 15/10654 1.4241934531585374e-10 8.070429567898379e-10 3.518277805100038e-10 5295/4893/6464/5290/5335/1950/867/3320/6654/2885/1956/3845/3265 13 Human_T.cell_leukemia_virus_1 R-HSA-5637812 Signaling by EGFRvIII in Cancer 13/1332 15/10654 1.4241934531585374e-10 8.070429567898379e-10 3.518277805100038e-10 5295/4893/6464/5290/5335/1950/867/3320/6654/2885/1956/3845/3265 13 Human_T.cell_leukemia_virus_1 R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 31/1332 73/10654 1.4446904689883038e-10 8.149868206221013e-10 3.5529088238985426e-10 5684/11065/246184/7321/8697/8881/7316/10213/890/983/51433/5688/5687/5685/5683/5708/5686/119504/8900/51529/7324/64682/29945/10393/6233/51434/7311/25906/29882/7314/996 31 Human_T.cell_leukemia_virus_1 R-HSA-5673001 RAF/MAP kinase cascade 68/1332 249/10654 1.5676523456608048e-10 8.804047548398628e-10 3.8380962034270646e-10 818/815/5684/2674/3562/4893/6464/1437/3667/5604/2904/3561/10048/817/1439/5594/3568/2064/1438/4684/7316/10213/1950/3560/2263/3718/2668/6714/5605/2261/5688/5159/3567/5687/3558/3717/5685/2244/5683/5708/5686/2335/2534/408/1445/816/1847/3563/5979/6654/6233/5527/2885/3716/8660/7311/8826/7450/1956/60/5536/1843/3845/3265/3559/5245/7314/5595 68 Human_T.cell_leukemia_virus_1 R-HSA-1643713 Signaling by EGFR in Cancer 17/1332 25/10654 1.633455588234285e-10 9.092420929197922e-10 3.9638116510016883e-10 5295/4893/6464/5290/5335/7316/1950/867/3320/6654/6233/2885/7311/1956/3845/3265/7314 17 Human_T.cell_leukemia_virus_1 R-HSA-9006115 Signaling by NTRK2 (TRKB) 17/1332 25/10654 1.633455588234285e-10 9.092420929197922e-10 3.9638116510016883e-10 5295/627/4893/6464/5290/5335/4915/2904/6714/2534/6654/2885/8851/3845/3265/1020/5781 17 Human_T.cell_leukemia_virus_1 R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 27/1332 58/10654 1.7494031029285642e-10 9.527052396035212e-10 4.1532878406278515e-10 8841/9734/55869/51564/55534/84441/10013/10046/7316/9611/9612/1024/4609/10014/22938/8850/1387/2033/55294/3066/3065/9794/6233/7311/3516/4851/7314 27 Human_T.cell_leukemia_virus_1 R-HSA-2644603 Signaling by NOTCH1 in Cancer 27/1332 58/10654 1.7494031029285642e-10 9.527052396035212e-10 4.1532878406278515e-10 8841/9734/55869/51564/55534/84441/10013/10046/7316/9611/9612/1024/4609/10014/22938/8850/1387/2033/55294/3066/3065/9794/6233/7311/3516/4851/7314 27 Human_T.cell_leukemia_virus_1 R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 27/1332 58/10654 1.7494031029285642e-10 9.527052396035212e-10 4.1532878406278515e-10 8841/9734/55869/51564/55534/84441/10013/10046/7316/9611/9612/1024/4609/10014/22938/8850/1387/2033/55294/3066/3065/9794/6233/7311/3516/4851/7314 27 Human_T.cell_leukemia_virus_1 R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 27/1332 58/10654 1.7494031029285642e-10 9.527052396035212e-10 4.1532878406278515e-10 8841/9734/55869/51564/55534/84441/10013/10046/7316/9611/9612/1024/4609/10014/22938/8850/1387/2033/55294/3066/3065/9794/6233/7311/3516/4851/7314 27 Human_T.cell_leukemia_virus_1 R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 27/1332 58/10654 1.7494031029285642e-10 9.527052396035212e-10 4.1532878406278515e-10 8841/9734/55869/51564/55534/84441/10013/10046/7316/9611/9612/1024/4609/10014/22938/8850/1387/2033/55294/3066/3065/9794/6233/7311/3516/4851/7314 27 Human_T.cell_leukemia_virus_1 R-HSA-212165 Epigenetic regulation of gene expression 48/1332 149/10654 1.9854757518009185e-10 1.0742242676271373e-9 4.683046133660267e-10 8467/5434/5440/902/2146/1788/9112/9219/404672/5931/5441/26147/11335/5435/9031/4331/1108/2966/8850/5928/2932/29947/5437/57459/1789/2965/54815/3720/2033/23512/2068/3066/3065/2071/1107/2968/57504/84172/2967/22823/6908/23411/60/8726/53615/1022/10919/9188 48 Human_T.cell_leukemia_virus_1 R-HSA-983705 Signaling by the B Cell Receptor (BCR) 40/1332 112/10654 1.9896204638881e-10 1.0742242676271373e-9 4.683046133660267e-10 5295/5777/5684/4893/4773/4790/6885/5579/5966/4772/5532/4775/930/8517/5530/7316/10213/5970/4792/6850/8915/5688/5687/4067/5685/5683/5708/5686/2534/695/6654/6233/2885/7409/7311/5293/3845/3265/3551/7314 40 Human_T.cell_leukemia_virus_1 R-HSA-69231 Cyclin D associated events in G1 23/1332 44/10654 2.083091904936945e-10 1.1151189857066708e-9 4.861325341420597e-10 25/1019/902/1029/7027/1027/5925/7316/1869/4331/1026/6714/1031/4067/3717/6502/1021/595/6233/1032/7311/1022/7314 23 Human_T.cell_leukemia_virus_1 R-HSA-69236 G1 Phase 23/1332 44/10654 2.083091904936945e-10 1.1151189857066708e-9 4.861325341420597e-10 25/1019/902/1029/7027/1027/5925/7316/1869/4331/1026/6714/1031/4067/3717/6502/1021/595/6233/1032/7311/1022/7314 23 Human_T.cell_leukemia_virus_1 R-HSA-6807505 RNA polymerase II transcribes snRNA genes 31/1332 74/10654 2.192060521330913e-10 1.168479718573851e-9 5.093949739578081e-10 2963/5434/5440/55197/2959/5430/5436/5451/5441/5438/5431/5435/5433/2960/6667/2962/5437/8812/905/5439/6827/1025/6908/79035/904/6829/2961/1022/5432/8178/2957 31 Human_T.cell_leukemia_virus_1 R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 16/1332 23/10654 3.396767678302779e-10 1.8030100165843442e-9 7.860164158986222e-10 7321/6497/51592/54778/7316/9611/9612/4089/7050/4088/142/3065/4087/6233/7311/7314 16 Human_T.cell_leukemia_virus_1 R-HSA-69190 DNA strand elongation 19/1332 32/10654 4.2797160570234214e-10 2.262135630140951e-9 9.86170749981956e-10 4172/6118/2237/8318/1763/57804/5982/3978/5425/5111/4171/6119/5985/5984/5983/6117/5981/10714/5424 19 Human_T.cell_leukemia_virus_1 R-HSA-9006936 Signaling by TGF-beta family members 37/1332 102/10654 5.724508573465842e-10 3.013151374652732e-9 1.3135736475559145e-9 5590/7027/7321/6497/51592/3726/54778/7316/9611/5501/9612/1024/6667/4092/4609/4089/22938/867/8812/7050/4088/142/905/3065/9040/4087/5499/6233/7514/1025/7311/387/7040/904/4090/7314/4221 37 Human_T.cell_leukemia_virus_1 R-HSA-110312 Translesion synthesis by REV1 13/1332 16/10654 6.722452248680667e-10 3.523685387016783e-9 1.536139307702907e-9 6118/5982/7316/5111/6119/5985/5984/6233/7311/5983/6117/5981/7314 13 Human_T.cell_leukemia_virus_1 R-HSA-1980143 Signaling by NOTCH1 30/1332 73/10654 7.518363682381141e-10 3.924523449143351e-9 1.710883371269087e-9 8841/9734/55869/51564/55534/84441/3091/10013/10046/7316/9611/9612/1024/4609/10014/22938/8850/1387/2033/408/55294/3066/3065/83737/9794/6233/7311/3516/4851/7314 30 Human_T.cell_leukemia_virus_1 R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 16/1332 24/10654 9.007066246823539e-10 4.670183290523886e-9 2.0359513801045475e-9 596/2309/207/5594/6722/1027/1950/10000/595/2002/208/7514/1385/2353/1956/5595 16 Human_T.cell_leukemia_virus_1 R-HSA-174437 Removal of the Flap Intermediate from the C-strand 10/1332 10/10654 9.058225142192594e-10 4.670183290523886e-9 2.0359513801045475e-9 6118/2237/1763/57804/5425/5111/6119/6117/10714/5424 10 Human_T.cell_leukemia_virus_1 R-HSA-450341 Activation of the AP-1 family of transcription factors 10/1332 10/10654 9.058225142192594e-10 4.670183290523886e-9 2.0359513801045475e-9 3725/5601/5594/1432/5602/2353/1386/5599/5600/5595 10 Human_T.cell_leukemia_virus_1 R-HSA-877312 Regulation of IFNG signaling 12/1332 14/10654 9.964826078243344e-10 5.095833823752084e-9 2.221512360618221e-9 3460/5777/9021/6772/8651/3459/7341/3717/3458/3716/5781/8554 12 Human_T.cell_leukemia_virus_1 R-HSA-8983432 Interleukin-15 signaling 12/1332 14/10654 9.964826078243344e-10 5.095833823752084e-9 2.221512360618221e-9 6464/3561/6776/3560/6774/3718/6654/2885/3716/9846/6777/3600 12 Human_T.cell_leukemia_virus_1 R-HSA-5621481 C-type lectin receptors (CLRs) 45/1332 142/10654 1.3265261288546343e-9 6.7561533202393935e-9 2.9453233033593204e-9 5684/9252/4893/4773/4790/6885/4772/7321/5567/3553/5532/5568/4775/4582/841/8517/5530/7316/10213/5970/4792/6850/8915/6714/5566/5688/1387/5687/4067/5685/5683/5708/5686/2534/2033/9040/7189/6233/7311/3845/7334/3265/3551/2207/7314 45 Human_T.cell_leukemia_virus_1 R-HSA-6804760 Regulation of TP53 Activity through Methylation 14/1332 19/10654 1.351519640675757e-9 6.855692370847187e-9 2.9887170322244034e-9 11200/472/79813/7316/4194/2033/7157/91875/6233/7311/26013/10919/7314/4193 14 Human_T.cell_leukemia_virus_1 R-HSA-202403 TCR signaling 40/1332 119/10654 1.5883889299469011e-9 8.024872585836151e-9 3.4984173853406696e-9 5295/5684/3635/5290/5335/4790/6885/5291/7321/3937/5788/8517/919/7316/10213/5970/4792/8915/5688/5687/915/5588/5685/917/5683/5708/5686/5728/1445/916/7189/7535/6233/26191/7311/3932/5296/7334/3551/7314 40 Human_T.cell_leukemia_virus_1 R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 27/1332 63/10654 1.7410785160918328e-9 8.761107092974102e-9 3.8193764500372415e-9 3665/5434/5440/6737/4790/1499/7520/5441/8517/6778/5591/5435/7316/51428/5970/4792/1387/5437/2033/1660/3661/6233/7311/3551/10621/2547/7314 27 Human_T.cell_leukemia_virus_1 R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 28/1332 67/10654 1.750190953639517e-9 8.771873385173357e-9 3.824069980483071e-9 5684/11065/246184/7321/8697/8881/7316/10213/51433/5688/5687/5685/5683/5708/5686/119504/51529/7324/64682/29945/10393/6233/51434/7311/25906/29882/7314/996 28 Human_T.cell_leukemia_virus_1 R-HSA-187687 Signalling to ERKs 19/1332 34/10654 1.7833986442287076e-9 8.90283926364966e-9 3.881164133847773e-9 4893/6464/5604/5594/9261/6714/5605/1432/4914/4803/5603/6654/2885/3845/5600/3265/1399/6300/5595 19 Human_T.cell_leukemia_virus_1 R-HSA-4655427 SUMOylation of DNA methylation proteins 13/1332 17/10654 2.5287774194712216e-9 1.2475301936058027e-8 5.4385677421857855e-9 1912/1788/8535/6045/80012/1911/7341/84733/1789/57332/7329/648/6015 13 Human_T.cell_leukemia_virus_1 R-HSA-5656121 Translesion synthesis by POLI 13/1332 17/10654 2.5287774194712216e-9 1.2475301936058027e-8 5.4385677421857855e-9 6118/5982/7316/5111/6119/5985/5984/6233/7311/5983/6117/5981/7314 13 Human_T.cell_leukemia_virus_1 R-HSA-9034015 Signaling by NTRK3 (TRKC) 13/1332 17/10654 2.5287774194712216e-9 1.2475301936058027e-8 5.4385677421857855e-9 5295/5800/4893/6464/5290/3667/5335/6714/6654/2885/3845/3265/25920 13 Human_T.cell_leukemia_virus_1 R-HSA-5693571 Nonhomologous End-Joining (NHEJ) 28/1332 69/10654 3.895152953841324e-9 1.914102506223588e-8 8.344468293385401e-9 10111/51588/7518/7520/51720/472/7336/3981/580/5591/29086/64421/9656/22976/7341/10524/4683/55775/165918/8924/672/7158/9025/79184/7334/2547/79840/55183 28 Human_T.cell_leukemia_virus_1 R-HSA-167044 Signalling to RAS 14/1332 20/10654 3.985554512465857e-9 1.9509056718607192e-8 8.504910509910759e-9 4893/6464/9261/6714/1432/4914/4803/5603/6654/2885/3845/5600/3265/6300 14 Human_T.cell_leukemia_virus_1 R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 17/1332 29/10654 4.778112385908045e-9 2.3297927835164035e-8 1.0156656683223549e-8 2308/2309/23410/4287/6720/5443/4089/4088/2908/4852/3630/3066/3065/6648/4087/2538/10891 17 Human_T.cell_leukemia_virus_1 R-HSA-2172127 DAP12 interactions 21/1332 43/10654 6.383304129083469e-9 3.100462005554827e-8 1.3516364361928419e-8 5295/4893/6464/5290/5335/5291/3937/3824/567/6850/9436/2534/22914/695/6654/2885/3133/3932/5296/3845/3265 21 Human_T.cell_leukemia_virus_1 R-HSA-209560 NF-kB is activated and signals survival 11/1332 13/10654 6.89281641106234e-9 3.335062709660163e-8 1.453909858365781e-8 4790/8878/7316/5970/4792/4803/7189/6233/7311/3551/7314 11 Human_T.cell_leukemia_virus_1 R-HSA-1059683 Interleukin-6 signaling 10/1332 11/10654 8.83900315829285e-9 4.2440709821116054e-8 1.8501890901850445e-8 9021/6774/6772/867/3717/3716/3570/5781/3569/3572 10 Human_T.cell_leukemia_virus_1 R-HSA-2586552 Signaling by Leptin 10/1332 11/10654 8.83900315829285e-9 4.2440709821116054e-8 1.8501890901850445e-8 3667/3953/9021/3952/6776/6774/3717/8660/6777/5781 10 Human_T.cell_leukemia_virus_1 R-HSA-4090294 SUMOylation of intracellular receptors 17/1332 30/10654 9.74443173852509e-9 4.643369366312335e-8 2.0242619361130673e-8 5468/51588/6613/2516/5465/4929/2099/2494/7341/2908/7067/7329/367/9063/7421/10062/8554 17 Human_T.cell_leukemia_virus_1 R-HSA-6804758 Regulation of TP53 Activity through Acetylation 17/1332 30/10654 9.74443173852509e-9 4.643369366312335e-8 2.0242619361130673e-8 9219/207/5931/1108/5928/57459/10000/54815/2033/3066/3065/7157/1107/5371/208/5300/53615 17 Human_T.cell_leukemia_virus_1 R-HSA-5687128 MAPK6/MAPK4 signaling 32/1332 89/10654 1.0675698182175976e-8 5.050122049389727e-8 2.201584459653625e-8 2308/2118/3725/5684/2309/5567/57690/5568/3315/27327/192670/7316/10213/983/5597/4609/5566/5688/5687/5685/5683/5708/5686/192669/23112/6233/7514/7311/4343/26523/8202/7314 32 Human_T.cell_leukemia_virus_1 R-HSA-202424 Downstream TCR signaling 34/1332 98/10654 1.0678318482811346e-8 5.050122049389727e-8 2.201584459653625e-8 5295/5684/3635/5290/4790/6885/5291/7321/8517/919/7316/10213/5970/4792/8915/5688/5687/915/5588/5685/917/5683/5708/5686/5728/916/7189/6233/7311/3932/5296/7334/3551/7314 34 Human_T.cell_leukemia_virus_1 R-HSA-203927 MicroRNA (miRNA) biogenesis 15/1332 24/10654 1.1481181616776e-8 5.3893009230985856e-8 2.3494483984054582e-8 5434/5440/5430/5436/5441/192670/5438/5431/5435/5433/5437/5439/192669/26523/5432 15 Human_T.cell_leukemia_virus_1 R-HSA-982772 Growth hormone receptor signaling 15/1332 24/10654 1.1481181616776e-8 5.3893009230985856e-8 2.3494483984054582e-8 5777/3667/9021/5594/6776/6774/6772/8651/4067/3717/8660/1154/5617/6777/5595 15 Human_T.cell_leukemia_virus_1 R-HSA-157118 Signaling by NOTCH 61/1332 235/10654 1.1626376663228963e-8 5.437167971130868e-8 2.3703158839922875e-8 1999/3725/5684/8841/9734/7027/55869/207/51564/55534/57690/27327/84441/3091/51548/10013/10046/192670/7316/10213/1950/1869/9611/9612/1024/6772/4609/10014/22938/8850/5688/1387/5687/4088/5685/5683/5708/5686/2033/408/595/55294/3002/4853/192669/3066/3065/7157/83737/861/23112/9794/6233/1385/7311/1956/4343/26523/3516/4851/7314 61 Human_T.cell_leukemia_virus_1 R-HSA-4420097 VEGFA-VEGFR2 Pathway 34/1332 99/10654 1.433927173597329e-8 6.681038460686814e-8 2.912577222004711e-8 5295/5590/4893/5290/5335/5579/5291/1499/5567/207/7422/5578/5568/3315/9261/6714/5566/1432/10000/3320/2534/4846/5603/208/2475/7409/2185/387/60/5296/3845/5600/3265/6300 34 Human_T.cell_leukemia_virus_1 R-HSA-177929 Signaling by EGFR 22/1332 49/10654 1.9827174977073405e-8 9.203906317770605e-8 4.012413347467564e-8 5295/4893/6464/5290/5335/8027/7316/1950/6714/867/6455/1445/6654/6233/2885/7311/1956/3845/3265/5781/10254/7314 22 Human_T.cell_leukemia_virus_1 R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 15/1332 25/10654 2.538559792929267e-8 1.165513948724459e-7 5.0810205613374884e-8 9252/5594/4205/9261/5598/1432/4208/466/6195/2002/1385/6196/6197/5600/5595 15 Human_T.cell_leukemia_virus_1 R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 15/1332 25/10654 2.538559792929267e-8 1.165513948724459e-7 5.0810205613374884e-8 2308/2309/842/207/1027/6199/1026/2932/3164/10000/208/2475/1385/2931/4193 15 Human_T.cell_leukemia_virus_1 R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 15/1332 25/10654 2.538559792929267e-8 1.165513948724459e-7 5.0810205613374884e-8 1017/994/902/51400/891/993/890/4331/983/995/8900/7514/5347/7465/1022 15 Human_T.cell_leukemia_virus_1 R-HSA-1236974 ER-Phagosome pathway 30/1332 83/10654 2.6677485572093855e-8 1.2203737036252387e-7 5.320179897822353e-8 3135/5684/3107/6890/811/6892/7099/8517/6810/9554/6891/7316/10213/567/3106/5688/5687/5685/5683/5708/5686/2923/695/6233/7311/3133/3134/3551/3105/7314 30 Human_T.cell_leukemia_virus_1 R-HSA-388841 Costimulation by the CD28 family 27/1332 70/10654 2.6919758473981652e-8 1.2269947884155407e-7 5.349044303945249e-8 5295/5777/5290/207/941/919/6714/8503/29126/4067/915/917/10000/2534/1445/916/942/208/5527/2885/2475/7409/3932/5296/5781/1493/940 27 Human_T.cell_leukemia_virus_1 R-HSA-1236394 Signaling by ERBB4 24/1332 58/10654 3.202964623871176e-8 1.4546315873032271e-7 6.341419604928302e-8 5295/4893/6464/5290/51741/348/6776/7316/1950/9611/4734/10413/6714/2099/83737/6285/6654/6233/2885/7311/1956/3845/3265/7314 24 Human_T.cell_leukemia_virus_1 R-HSA-73863 RNA Polymerase I Transcription Termination 17/1332 32/10654 3.595513445506298e-8 1.6270345015996126e-7 7.093004563077551e-8 5434/5440/902/404672/5441/5435/4331/2966/5437/2965/2068/2071/2968/84172/2967/6908/1022 17 Human_T.cell_leukemia_virus_1 R-HSA-109581 Apoptosis 49/1332 178/10654 4.4209305189133236e-8 1.9933801407860077e-7 8.690076590657768e-8 596/5684/7186/1499/10018/7531/1029/7027/842/356/207/5594/63967/355/841/7099/7316/10213/1869/6774/54205/5339/3146/5688/5687/999/5588/836/5685/5683/5708/10000/5686/4137/3002/7157/208/6233/7311/7161/1630/5599/7431/57099/637/8795/6304/7314/5595 49 Human_T.cell_leukemia_virus_1 R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 21/1332 47/10654 4.6283016380274744e-8 2.057386381851082e-7 8.969109739305614e-8 818/815/4893/5604/817/5594/6714/5605/3717/2244/2335/408/1445/816/8826/7450/60/3845/3265/5245/5595 21 Human_T.cell_leukemia_virus_1 R-HSA-6802949 Signaling by RAS mutants 21/1332 47/10654 4.6283016380274744e-8 2.057386381851082e-7 8.969109739305614e-8 818/815/4893/5604/817/5594/6714/5605/3717/2244/2335/408/1445/816/8826/7450/60/3845/3265/5245/5595 21 Human_T.cell_leukemia_virus_1 R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 21/1332 47/10654 4.6283016380274744e-8 2.057386381851082e-7 8.969109739305614e-8 818/815/4893/5604/817/5594/6714/5605/3717/2244/2335/408/1445/816/8826/7450/60/3845/3265/5245/5595 21 Human_T.cell_leukemia_virus_1 R-HSA-9649948 Signaling downstream of RAS mutants 21/1332 47/10654 4.6283016380274744e-8 2.057386381851082e-7 8.969109739305614e-8 818/815/4893/5604/817/5594/6714/5605/3717/2244/2335/408/1445/816/8826/7450/60/3845/3265/5245/5595 21 Human_T.cell_leukemia_virus_1 R-HSA-3371511 HSF1 activation 10/1332 12/10654 4.705176951258714e-8 2.084194579113895e-7 9.085979212771647e-8 6118/7531/1915/10013/7415/6119/3320/3326/6117/10728 10 Human_T.cell_leukemia_virus_1 R-HSA-381119 Unfolded Protein Response (UPR) 32/1332 94/10654 4.828068023558625e-8 2.1311261661883337e-7 9.290575956690836e-8 10525/10488/6464/1965/9695/84699/7184/7494/811/1051/1649/3576/468/4800/51726/3068/1054/10130/8894/3309/4801/22926/90993/9451/6347/2931/467/64764/8570/148327/9820/1968 32 Human_T.cell_leukemia_virus_1 R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 23/1332 55/10654 4.887170983493013e-8 2.144162018996048e-7 9.347405337603055e-8 596/351/4790/6885/842/841/8517/7316/5970/1432/837/5603/83737/7189/6233/3326/7311/5600/7334/1540/3551/6300/7314 23 Human_T.cell_leukemia_virus_1 R-HSA-168638 NOD1/2 Signaling Pathway 18/1332 36/10654 4.8916891848320016e-8 2.144162018996048e-7 9.347405337603055e-8 6885/842/841/8517/7316/1432/837/5603/83737/7189/6233/7311/5600/7334/1540/3551/6300/7314 18 Human_T.cell_leukemia_virus_1 R-HSA-6803529 FGFR2 alternative splicing 15/1332 26/10654 5.307098796473502e-8 2.3181702381818284e-7 1.0105988570770083e-7 2963/5434/5440/5430/5436/5441/5438/5431/5435/5433/2962/5437/4670/5439/5432 15 Human_T.cell_leukemia_virus_1 R-HSA-3232118 SUMOylation of transcription factors 13/1332 20/10654 5.713982477261208e-8 2.487262960690173e-7 1.0843142854318302e-7 7020/1029/9112/51588/6613/7341/7157/7329/7158/9063/4286/4193/8554 13 Human_T.cell_leukemia_virus_1 R-HSA-438064 Post NMDA receptor activation events 29/1332 81/10654 5.7922339671741854e-8 2.5126311485190085e-7 1.0953734652986393e-7 818/815/3838/4893/2904/5575/5567/817/5594/5568/5573/6714/5566/27330/5576/6195/4137/816/5577/1385/6196/84790/8536/6197/3845/3265/2891/814/5595 29 Human_T.cell_leukemia_virus_1 R-HSA-5654741 Signaling by FGFR3 19/1332 40/10654 5.990958128771872e-8 2.581036070546238e-7 1.1251943709769813e-7 5295/4893/6464/5290/5335/5594/7316/6714/2261/867/6654/6233/2885/7311/3845/3265/5781/7314/5595 19 Human_T.cell_leukemia_virus_1 R-HSA-6783310 Fanconi Anemia Pathway 19/1332 40/10654 5.990958128771872e-8 2.581036070546238e-7 1.1251943709769813e-7 6118/545/80198/2072/7316/197342/6119/84464/9937/2177/84126/55215/6233/2067/146956/7311/6117/57697/7314 19 Human_T.cell_leukemia_virus_1 R-HSA-110056 MAPK3 (ERK1) activation 9/1332 10/10654 6.473104910191331e-8 2.7418067262695943e-7 1.1952818210915058e-7 5604/983/3717/3716/3570/5781/3569/3572/5595 9 Human_T.cell_leukemia_virus_1 R-HSA-381183 ATF6 (ATF6-alpha) activates chaperone genes 9/1332 10/10654 6.473104910191331e-8 2.7418067262695943e-7 1.1952818210915058e-7 7184/7494/811/1649/468/4800/3309/4801/22926 9 Human_T.cell_leukemia_virus_1 R-HSA-390450 Folding of actin by CCT/TriC 9/1332 10/10654 6.473104910191331e-8 2.7418067262695943e-7 1.1952818210915058e-7 10694/10575/7203/10576/908/6950/10574/60/22948 9 Human_T.cell_leukemia_virus_1 R-HSA-8877330 RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) 9/1332 10/10654 6.473104910191331e-8 2.7418067262695943e-7 1.1952818210915058e-7 4773/865/3558/50943/3458/861/8784/3559/1493 9 Human_T.cell_leukemia_virus_1 R-HSA-9020958 Interleukin-21 signaling 9/1332 10/10654 6.473104910191331e-8 2.7418067262695943e-7 1.1952818210915058e-7 3561/6775/6776/50615/6774/3718/6772/3716/6777 9 Human_T.cell_leukemia_virus_1 R-HSA-2871809 FCERI mediated Ca+2 mobilization 17/1332 33/10654 6.554587748877251e-8 2.7577496281229373e-7 1.202232077861309e-7 6464/4773/2205/5335/4772/3937/5532/4775/2206/5530/6850/4067/695/6654/2885/7409/2207 17 Human_T.cell_leukemia_virus_1 R-HSA-389356 CD28 co-stimulation 17/1332 33/10654 6.554587748877251e-8 2.7577496281229373e-7 1.202232077861309e-7 5295/5290/207/941/6714/8503/4067/10000/2534/942/208/2885/2475/7409/3932/5296/940 17 Human_T.cell_leukemia_virus_1 R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 30/1332 86/10654 6.756884164390885e-8 2.8333867596012445e-7 1.235205841981632e-7 5295/25/5290/23646/5335/51517/5291/4771/5594/919/6850/10552/10094/6714/10092/4067/917/3320/2534/695/2885/10096/3326/10097/7409/60/5296/5581/10095/5595 30 Human_T.cell_leukemia_virus_1 R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 23/1332 56/10654 7.320577788963075e-8 3.059563740370614e-7 1.3338069690679356e-7 8841/23410/200186/5465/4209/9611/5469/54205/64784/4208/1387/6604/2101/6648/10498/84808/1385/23054/1386/23373/8648/814/10891 23 Human_T.cell_leukemia_virus_1 R-HSA-5357801 Programmed Cell Death 49/1332 181/10654 7.849820199742185e-8 3.269891990488632e-7 1.425498893016967e-7 596/5684/7186/1499/10018/7531/1029/7027/842/356/207/5594/63967/355/841/7099/7316/10213/1869/6774/54205/5339/3146/5688/5687/999/5588/836/5685/5683/5708/10000/5686/4137/3002/7157/208/6233/7311/7161/1630/5599/7431/57099/637/8795/6304/7314/5595 49 Human_T.cell_leukemia_virus_1 R-HSA-199418 Negative regulation of the PI3K/AKT network 35/1332 110/10654 8.010363655551849e-8 3.3257549434601406e-7 1.4498521676367947e-7 5295/5290/3667/5291/207/5594/930/941/2064/2100/1950/2263/6714/2099/8503/2261/5159/10000/2534/5728/3630/942/7189/208/5527/2885/7409/8660/3932/5293/1956/5296/5781/940/5595 35 Human_T.cell_leukemia_virus_1 R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 28/1332 78/10654 9.165787130455301e-8 3.792947437537095e-7 1.6535232323293672e-007 3665/351/7186/4790/7321/4214/841/7706/8517/7316/5970/4792/3146/1387/2033/83737/3661/7189/3439/6285/6233/7311/7187/5300/1540/3551/3456/7314 28 Human_T.cell_leukemia_virus_1 R-HSA-69183 Processive synthesis on the lagging strand 11/1332 15/10654 9.478762827689536e-8 3.909601192535553e-7 1.7043780615103534e-7 6118/2237/1763/57804/3978/5425/5111/6119/6117/10714/5424 11 Human_T.cell_leukemia_virus_1 R-HSA-1538133 G0 and Early G1 15/1332 27/10654 1.0562277986757098e-7 4.3422698390001396e-7 1.892998565910027e-7 1017/7027/7153/4149/1869/993/890/983/5111/4609/5928/990/3065/8900/1859 15 Human_T.cell_leukemia_virus_1 R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 29/1332 83/10654 1.0717102180722344e-7 4.391568255162446e-7 1.9144900518279932e-7 5684/4893/4773/4790/6885/5579/5966/4772/5532/4775/8517/5530/7316/10213/5970/4792/8915/5688/5687/5685/5683/5708/5686/6233/7311/3845/3265/3551/7314 29 Human_T.cell_leukemia_virus_1 R-HSA-109606 Intrinsic Pathway for Apoptosis 22/1332 53/10654 1.1208809773706672e-7 4.578143732247725e-7 1.9958270307932932e-7 596/10018/7531/1029/7027/842/207/5594/841/1869/6774/54205/836/10000/3002/7157/208/7161/5599/57099/637/5595 22 Human_T.cell_leukemia_virus_1 R-HSA-210993 Tie2 Signaling 12/1332 18/10654 1.2514518196578956e-7 5.094907408186513e-7 2.221108492732971e-7 5295/4893/6464/5290/5291/6654/2885/5296/3845/3265/5781/9046 12 Human_T.cell_leukemia_virus_1 R-HSA-194138 Signaling by VEGF 34/1332 107/10654 1.2700954693499564e-7 5.154129356265307e-7 2.2469261104629115e-7 5295/5590/4893/5290/5335/5579/5291/1499/5567/207/7422/5578/5568/3315/9261/6714/5566/1432/10000/3320/2534/4846/5603/208/2475/7409/2185/387/60/5296/3845/5600/3265/6300 34 Human_T.cell_leukemia_virus_1 R-HSA-5621575 CD209 (DC-SIGN) signaling 13/1332 21/10654 1.328018094109473e-7 5.371854541446035e-7 2.3418427044543425e-7 9252/4893/4790/5567/5568/5970/5566/1387/4067/2534/2033/3845/3265 13 Human_T.cell_leukemia_virus_1 R-HSA-5617472 Activation of anterior HOX genes in hindbrain development during early embryogenesis 37/1332 122/10654 1.382348089879921e-7 5.555891044948691e-7 2.4220728260549487e-7 9070/3725/5434/5440/8841/11091/4211/2146/5430/8085/5436/5929/5931/5441/3213/5438/5431/7403/5435/5433/9611/9935/5928/22976/1387/5437/2033/23512/5439/58508/23054/9063/8726/8202/5432/1959/7528 37 Human_T.cell_leukemia_virus_1 R-HSA-5619507 Activation of HOX genes during differentiation 37/1332 122/10654 1.382348089879921e-7 5.555891044948691e-7 2.4220728260549487e-7 9070/3725/5434/5440/8841/11091/4211/2146/5430/8085/5436/5929/5931/5441/3213/5438/5431/7403/5435/5433/9611/9935/5928/22976/1387/5437/2033/23512/5439/58508/23054/9063/8726/8202/5432/1959/7528 37 Human_T.cell_leukemia_virus_1 R-HSA-3371556 Cellular response to heat stress 30/1332 89/10654 1.619593824615125e-7 6.488691182693718e-7 2.828724045003286e-7 818/6118/815/573/7531/1915/817/5594/3308/10013/545/472/9261/7415/6119/2932/1387/57805/3309/3320/2033/7266/816/3326/2475/23411/6117/3312/10728/5595 30 Human_T.cell_leukemia_virus_1 R-HSA-8848021 Signaling by PTK6 22/1332 54/10654 1.6700153608459613e-7 6.648352290962719e-7 2.8983277914748365e-7 1017/1019/4893/207/9021/1027/3091/2064/7316/1950/6774/867/2908/595/6233/7311/2034/387/1956/3845/3265/7314 22 Human_T.cell_leukemia_virus_1 R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 22/1332 54/10654 1.6700153608459613e-7 6.648352290962719e-7 2.8983277914748365e-7 1017/1019/4893/207/9021/1027/3091/2064/7316/1950/6774/867/2908/595/6233/7311/2034/387/1956/3845/3265/7314 22 Human_T.cell_leukemia_virus_1 R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 14/1332 25/10654 2.486541948084403e-7 9.867727983249776e-7 4.3018042668171145e-7 3135/3107/6890/821/811/6892/6891/567/3106/3309/2923/3133/3134/3105 14 Human_T.cell_leukemia_virus_1 R-HSA-446652 Interleukin-1 family signaling 40/1332 140/10654 2.5980651447931763e-7 1.0277880352672377e-6 4.480608872682042e-7 5777/5684/351/4790/6885/5604/3553/8878/25930/8517/7316/3565/10213/79155/6774/5970/4792/3606/8809/3146/3552/5688/5687/4088/5685/5683/5708/5686/57162/7189/6285/6233/7311/5599/7334/3551/6416/5781/7314/3596 40 Human_T.cell_leukemia_virus_1 R-HSA-69615 G1/S DNA Damage Checkpoints 25/1332 68/10654 2.6224479385882494e-7 1.0341816635561185e-6 4.5084816895049597e-7 1017/5684/1029/1027/11200/472/7316/10213/993/890/1026/4194/5688/5687/5685/5683/5708/5686/1111/7157/8900/6233/7311/7314/4193 25 Human_T.cell_leukemia_virus_1 R-HSA-193639 p75NTR signals via NF-kB 11/1332 16/10654 2.689251551810423e-7 1.0506454820427057e-6 4.5802551765061466e-7 4790/8878/7316/5970/4792/4803/7189/6233/7311/3551/7314 11 Human_T.cell_leukemia_virus_1 R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 11/1332 16/10654 2.689251551810423e-7 1.0506454820427057e-6 4.5802551765061466e-7 55534/84441/10046/22938/8850/1387/2033/9794/3516/4851/6928 11 Human_T.cell_leukemia_virus_1 R-HSA-9614657 FOXO-mediated transcription of cell death genes 11/1332 16/10654 2.689251551810423e-7 1.0506454820427057e-6 4.5802551765061466e-7 2308/2309/10018/356/1649/4800/1387/6794/2033/4801/604 11 Human_T.cell_leukemia_virus_1 R-HSA-381042 PERK regulates gene expression 16/1332 32/10654 2.747947032271479e-7 1.070253054674155e-6 4.6657337585577336e-7 1965/1051/1649/3576/468/4800/1054/8894/3309/4801/22926/9451/6347/467/8570/1968 16 Human_T.cell_leukemia_virus_1 R-HSA-389357 CD28 dependent PI3K/Akt signaling 13/1332 22/10654 2.8744647145208267e-7 1.116073028045432e-6 4.865484458301985e-7 5295/5290/207/941/8503/10000/2534/942/208/2475/3932/5296/940 13 Human_T.cell_leukemia_virus_1 R-HSA-5607764 CLEC7A (Dectin-1) signaling 32/1332 101/10654 3.192945310569302e-7 1.2359154463680562e-6 5.387933625284556e-7 5684/4773/4790/6885/4772/7321/3553/5532/4775/841/8517/5530/7316/10213/5970/4792/6850/8915/6714/5688/5687/5685/5683/5708/5686/9040/7189/6233/7311/7334/3551/7314 32 Human_T.cell_leukemia_virus_1 R-HSA-1266695 Interleukin-7 signaling 17/1332 36/10654 3.3360603467856317e-7 1.2873508945571549e-6 5.612164806830205e-7 5295/3667/6597/64109/3561/6776/6774/3718/8651/8503/3716/8660/1154/3575/5296/6777/3574 17 Human_T.cell_leukemia_virus_1 R-HSA-383280 Nuclear Receptor transcription pathway 21/1332 52/10654 3.8018814404349346e-7 1.4626198324364366e-6 6.3762441025804e-7 7182/5468/3172/2516/5465/2100/4929/9611/5469/2063/9612/2099/7101/2494/2908/3164/2101/7067/367/7421/10062 21 Human_T.cell_leukemia_virus_1 R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 32/1332 103/10654 5.250045086778455e-7 2.0135843655997857e-6 8.778156258702102e-7 5295/5290/3667/5291/207/5594/930/941/2064/2100/1950/2263/6714/2099/8503/2261/5159/2534/3630/942/7189/5527/2885/7409/8660/3932/5293/1956/5296/5781/940/5595 32 Human_T.cell_leukemia_virus_1 R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 28/1332 84/10654 5.410422182608618e-7 2.0687875701281586e-6 9.018812852788643e-7 7124/1019/8841/4790/5468/6721/1051/6720/3952/688/5465/9611/5469/1050/5970/9612/1024/1387/6604/2033/10498/4023/23054/7040/8202/8648/1959/10891 28 Human_T.cell_leukemia_virus_1 R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 17/1332 37/10654 5.45622763948415e-7 2.0799801122639578e-6 9.067606380131555e-7 8841/57690/27327/192670/348/9611/2874/9612/2033/192669/9682/23028/23112/4343/26523/8648/10062 17 Human_T.cell_leukemia_virus_1 R-HSA-174411 Polymerase switching on the C-strand of the telomere 10/1332 14/10654 5.6192054525451e-7 2.1101374505378312e-6 9.19907632608326e-7 57804/5982/5425/5111/5985/5984/5983/5981/10714/5424 10 Human_T.cell_leukemia_virus_1 R-HSA-69091 Polymerase switching 10/1332 14/10654 5.6192054525451e-7 2.1101374505378312e-6 9.19907632608326e-7 57804/5982/5425/5111/5985/5984/5983/5981/10714/5424 10 Human_T.cell_leukemia_virus_1 R-HSA-69109 Leading Strand Synthesis 10/1332 14/10654 5.6192054525451e-7 2.1101374505378312e-6 9.19907632608326e-7 57804/5982/5425/5111/5985/5984/5983/5981/10714/5424 10 Human_T.cell_leukemia_virus_1 R-HSA-69166 Removal of the Flap Intermediate 10/1332 14/10654 5.6192054525451e-7 2.1101374505378312e-6 9.19907632608326e-7 6118/2237/1763/57804/5425/5111/6119/6117/10714/5424 10 Human_T.cell_leukemia_virus_1 R-HSA-8941856 RUNX3 regulates NOTCH signaling 10/1332 14/10654 5.6192054525451e-7 2.1101374505378312e-6 9.19907632608326e-7 55534/84441/10046/22938/8850/1387/2033/9794/3516/4851 10 Human_T.cell_leukemia_virus_1 R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 26/1332 75/10654 5.778821443559559e-7 2.163618266666049e-6 9.432224223353791e-7 5295/5290/3667/5291/930/941/2064/2100/1950/2263/6714/2099/8503/2261/5159/2534/942/2885/7409/8660/3932/5293/1956/5296/5781/940 26 Human_T.cell_leukemia_virus_1 R-HSA-112409 RAF-independent MAPK1/3 activation 13/1332 23/10654 5.854574404791722e-7 2.1790102370497e-6 9.49932502303484e-7 5604/5594/983/5605/3717/1847/3716/1843/3570/5781/3569/3572/5595 13 Human_T.cell_leukemia_virus_1 R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 13/1332 23/10654 5.854574404791722e-7 2.1790102370497e-6 9.49932502303484e-7 5601/6885/8517/7316/5602/7189/5609/6233/7311/5599/7334/6416/7314 13 Human_T.cell_leukemia_virus_1 R-HSA-5654743 Signaling by FGFR4 18/1332 41/10654 5.872023220099774e-7 2.1790575843320106e-6 9.499531431988768e-7 5295/4893/6464/5290/5335/5594/7316/6714/867/6654/6233/2885/7311/3845/3265/5781/7314/5595 18 Human_T.cell_leukemia_virus_1 R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 15/1332 30/10654 6.525346884182695e-7 2.4143783471475972e-6 1.0525404726499023e-6 818/815/4893/2904/817/5594/27330/6195/816/1385/6196/6197/3845/3265/5595 15 Human_T.cell_leukemia_virus_1 R-HSA-8876384 Listeria monocytogenes entry into host cells 12/1332 20/10654 6.66677358593865e-7 2.452281044184451e-6 1.0690640314786201e-6 1499/8027/7316/6714/867/999/6455/6233/2885/7311/10254/7314 12 Human_T.cell_leukemia_virus_1 R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 12/1332 20/10654 6.66677358593865e-7 2.452281044184451e-6 1.0690640314786201e-6 55534/84441/10046/22938/8850/1387/4088/2033/4853/9794/3516/4851 12 Human_T.cell_leukemia_virus_1 R-HSA-69002 DNA Replication Pre-Initiation 28/1332 85/10654 7.118546922111864e-7 2.6108256641448176e-6 1.1381810484641036e-6 1017/4172/6118/5684/8318/23594/54107/7316/10213/1869/5426/4171/51053/6119/5688/5687/5427/5685/5683/5708/5686/990/81620/6233/7311/6117/7314/56655 28 Human_T.cell_leukemia_virus_1 R-HSA-74751 Insulin receptor signalling cascade 21/1332 54/10654 8.037552397441294e-7 2.9393142197619616e-6 1.2813845774378565e-6 5295/54106/4893/6464/5290/3667/5291/5594/2263/2261/3630/208/6654/2885/8660/9846/5296/3845/3265/5781/5595 21 Human_T.cell_leukemia_virus_1 R-HSA-73854 RNA Polymerase I Promoter Clearance 33/1332 110/10654 8.557975425955057e-7 3.1205603147395543e-6 1.3603982294195532e-6 5434/5440/902/9112/9219/404672/5931/5441/11335/5435/4331/1108/2966/8850/5928/5437/57459/2965/54815/2068/3066/3065/2071/1107/2968/57504/84172/2967/6908/53615/1022/10919/5595 33 Human_T.cell_leukemia_virus_1 R-HSA-111996 Ca-dependent events 17/1332 38/10654 8.729084996719895e-7 3.173754024818968e-6 1.3835878561883377e-6 818/815/3838/5575/5567/817/5578/5594/5568/5582/5573/5566/5576/816/5577/1385/814 17 Human_T.cell_leukemia_virus_1 R-HSA-1489509 DAG and IP3 signaling 18/1332 42/10654 9.082613503253972e-7 3.273904810055443e-6 1.4272482687966578e-6 818/815/3838/5335/5575/5567/817/5578/5568/5582/5573/5566/5576/816/5577/1385/5581/814 18 Human_T.cell_leukemia_virus_1 R-HSA-186712 Regulation of beta-cell development 18/1332 42/10654 9.082613503253972e-7 3.273904810055443e-6 1.4272482687966578e-6 2308/3172/207/55534/84441/10046/2494/22938/8850/1387/10000/2033/3630/208/9794/3516/4851/6928 18 Human_T.cell_leukemia_virus_1 R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 18/1332 42/10654 9.082613503253972e-7 3.273904810055443e-6 1.4272482687966578e-6 9070/6662/1487/1499/207/8085/5929/6657/7316/6934/3065/208/57680/6233/7514/7311/7314/4221 18 Human_T.cell_leukemia_virus_1 R-HSA-2197563 NOTCH2 intracellular domain regulates transcription 9/1332 12/10654 1.1238257148550576e-6 4.005021952656267e-6 1.7459764348873864e-6 55534/84441/10046/2033/3002/4853/9794/1385/3516 9 Human_T.cell_leukemia_virus_1 R-HSA-381033 ATF6 (ATF6-alpha) activates chaperones 9/1332 12/10654 1.1238257148550576e-6 4.005021952656267e-6 1.7459764348873864e-6 7184/7494/811/1649/468/4800/3309/4801/22926 9 Human_T.cell_leukemia_virus_1 R-HSA-8984722 Interleukin-35 Signalling 9/1332 12/10654 1.1238257148550576e-6 4.005021952656267e-6 1.7459764348873864e-6 6775/3595/821/6774/6772/3717/9466/3716/3572 9 Human_T.cell_leukemia_virus_1 R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 9/1332 12/10654 1.1238257148550576e-6 4.005021952656267e-6 1.7459764348873864e-6 5295/5290/5291/4067/3717/2057/2056/8660/5293 9 Human_T.cell_leukemia_virus_1 R-HSA-8940973 RUNX2 regulates osteoblast differentiation 13/1332 24/10654 1.1312608567518635e-6 4.009467841450117e-6 1.7479146058032892e-6 25/8841/5594/5925/10013/865/4094/10413/6714/23314/367/860/5595 13 Human_T.cell_leukemia_virus_1 R-HSA-2871837 FCERI mediated NF-kB activation 27/1332 82/10654 1.1314476023170044e-6 4.009467841450117e-6 1.7479146058032892e-6 5684/2205/4790/6885/7321/2206/8517/7316/10213/5970/4792/8915/5688/5687/4067/5588/5685/5683/5708/5686/7189/6233/7311/7334/3551/2207/7314 27 Human_T.cell_leukemia_virus_1 R-HSA-114604 GPVI-mediated activation cascade 16/1332 35/10654 1.2839579560679954e-6 4.537132327903197e-6 1.9779482410154513e-6 5295/5777/5590/5290/5291/3937/6850/8503/4067/2534/7409/3932/387/5296/5781/2207 16 Human_T.cell_leukemia_virus_1 R-HSA-9024446 NR1H2 and NR1H3-mediated signaling 19/1332 47/10654 1.3375891634134377e-6 4.713409432980685e-6 2.0547956778369487e-6 8841/8204/57690/27327/6720/192670/348/9611/2874/9612/2033/192669/9682/23028/23112/4343/26523/8648/10062 19 Human_T.cell_leukemia_virus_1 R-HSA-73864 RNA Polymerase I Transcription 33/1332 112/10654 1.3430135762662945e-6 4.719304689784912e-6 2.0573656960739177e-6 5434/5440/902/9112/9219/404672/5931/5441/11335/5435/4331/1108/2966/8850/5928/5437/57459/2965/54815/2068/3066/3065/2071/1107/2968/57504/84172/2967/6908/53615/1022/10919/5595 33 Human_T.cell_leukemia_virus_1 R-HSA-389513 CTLA4 inhibitory signaling 12/1332 21/10654 1.378511424171089e-6 4.830549781635738e-6 2.1058626359570076e-6 207/941/6714/4067/10000/2534/942/208/5527/3932/5781/1493 12 Human_T.cell_leukemia_virus_1 R-HSA-909733 Interferon alpha/beta signaling 24/1332 69/10654 1.458275870689808e-6 5.095864014799385e-6 2.221525522308158e-6 3135/3665/5777/3455/3107/9021/3662/3663/3664/6772/8651/3659/3106/1958/3454/3661/3439/3716/3133/3134/3456/5781/3105/3660 24 Human_T.cell_leukemia_virus_1 R-HSA-442755 Activation of NMDA receptors and postsynaptic events 29/1332 93/10654 1.632027833852264e-6 5.687232728493485e-6 2.4793308104301783e-6 818/815/3838/4893/2904/5575/5567/817/5594/5568/5573/6714/5566/27330/5576/6195/4137/816/5577/1385/6196/84790/8536/6197/3845/3265/2891/814/5595 29 Human_T.cell_leukemia_virus_1 R-HSA-8941326 RUNX2 regulates bone development 15/1332 32/10654 1.8631754451936643e-6 6.4747920167227335e-6 2.822664748316078e-6 25/8841/5594/5925/10013/865/4094/10413/6714/4089/2736/23314/367/860/5595 15 Human_T.cell_leukemia_virus_1 R-HSA-111933 Calmodulin induced events 16/1332 36/10654 2.0442394931795454e-6 7.0649815451095285e-6 3.0799559743971754e-006 818/815/3838/5575/5567/817/5578/5568/5582/5573/5566/5576/816/5577/1385/814 16 Human_T.cell_leukemia_virus_1 R-HSA-111997 CaM pathway 16/1332 36/10654 2.0442394931795454e-6 7.0649815451095285e-6 3.0799559743971754e-006 818/815/3838/5575/5567/817/5578/5568/5582/5573/5566/5576/816/5577/1385/814 16 Human_T.cell_leukemia_virus_1 R-HSA-5685939 HDR through MMEJ (alt-NHEJ) 8/1332 10/10654 2.0867229045456747e-6 7.152853988878634e-6 3.1182636835459533e-6 2237/10111/7515/4683/142/5932/3980/10038 8 Human_T.cell_leukemia_virus_1 R-HSA-74749 Signal attenuation 8/1332 10/10654 2.0867229045456747e-6 7.152853988878634e-6 3.1182636835459533e-6 6464/3667/5594/3630/6654/2885/8660/5595 8 Human_T.cell_leukemia_virus_1 R-HSA-8853334 Signaling by FGFR3 fusions in cancer 8/1332 10/10654 2.0867229045456747e-6 7.152853988878634e-6 3.1182636835459533e-6 5295/4893/5290/2261/6654/2885/3845/3265 8 Human_T.cell_leukemia_virus_1 R-HSA-1236975 Antigen processing-Cross presentation 30/1332 99/10654 2.1171468139991833e-6 7.237420358725469e-6 3.1551301204049614e-6 3135/5684/3107/6890/811/6892/7099/8517/6810/9554/6891/7316/10213/567/3106/5688/5687/5685/5683/5708/5686/2923/695/6233/7311/3133/3134/3551/3105/7314 30 Human_T.cell_leukemia_virus_1 R-HSA-69563 p53-Dependent G1 DNA Damage Response 23/1332 66/10654 2.3175368089913385e-6 7.87962515057055e-6 3.4350972332417847e-6 1017/5684/1029/1027/11200/472/7316/10213/890/1026/4194/5688/5687/5685/5683/5708/5686/7157/8900/6233/7311/7314/4193 23 Human_T.cell_leukemia_virus_1 R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 23/1332 66/10654 2.3175368089913385e-6 7.87962515057055e-6 3.4350972332417847e-6 1017/5684/1029/1027/11200/472/7316/10213/890/1026/4194/5688/5687/5685/5683/5708/5686/7157/8900/6233/7311/7314/4193 23 Human_T.cell_leukemia_virus_1 R-HSA-6802957 Oncogenic MAPK signaling 24/1332 71/10654 2.612900013036989e-6 8.859914329920571e-6 3.862451147091137e-6 818/815/4893/5604/10018/10142/817/5594/8546/6714/5605/3717/2244/2335/408/1445/816/8826/7450/60/3845/3265/5245/5595 24 Human_T.cell_leukemia_virus_1 R-HSA-198753 ERK/MAPK targets 12/1332 22/10654 2.6877893674338943e-6 9.016637397951571e-6 3.9307740643735e-6 9252/5594/4205/5598/1432/4208/6195/2002/6196/6197/5600/5595 12 Human_T.cell_leukemia_virus_1 R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 12/1332 22/10654 2.6877893674338943e-6 9.016637397951571e-6 3.9307740643735e-6 3725/351/994/2309/10018/7531/356/993/995/6648/8851/1020 12 Human_T.cell_leukemia_virus_1 R-HSA-8863678 Neurodegenerative Diseases 12/1332 22/10654 2.6877893674338943e-6 9.016637397951571e-6 3.9307740643735e-6 3725/351/994/2309/10018/7531/356/993/995/6648/8851/1020 12 Human_T.cell_leukemia_virus_1 R-HSA-9613829 Chaperone Mediated Autophagy 12/1332 22/10654 2.6877893674338943e-6 9.016637397951571e-6 3.9307740643735e-6 1915/1080/10013/7316/3320/6233/3326/7311/7431/3312/11315/7314 12 Human_T.cell_leukemia_virus_1 R-HSA-1839126 FGFR2 mutant receptor activation 15/1332 33/10654 3.0227093374297826e-6 1.0059704620335096e-5 4.385495864107259e-6 2963/5434/5440/5430/5436/5441/5438/5431/5435/5433/2263/2962/5437/5439/5432 15 Human_T.cell_leukemia_virus_1 R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 15/1332 33/10654 3.0227093374297826e-6 1.0059704620335096e-5 4.385495864107259e-6 351/4790/6885/8517/7316/5970/4792/3146/7189/6285/6233/7311/7334/3551/7314 15 Human_T.cell_leukemia_virus_1 R-HSA-68962 Activation of the pre-replicative complex 15/1332 33/10654 3.0227093374297826e-6 1.0059704620335096e-5 4.385495864107259e-6 1017/4172/6118/8318/23594/54107/5426/4171/51053/6119/5427/990/81620/6117/56655 15 Human_T.cell_leukemia_virus_1 R-HSA-6802952 Signaling by BRAF and RAF fusions 23/1332 67/10654 3.116215737411633e-6 1.0343534030775289e-5 4.509230382423166e-6 818/815/4893/5604/10018/10142/817/5594/8546/6714/5605/3717/2244/2335/408/1445/816/8826/7450/60/3845/3265/5595 23 Human_T.cell_leukemia_virus_1 R-HSA-186797 Signaling by PDGF 21/1332 58/10654 3.1432806414630903e-6 1.0405913281475178e-5 4.53642441607277e-6 5295/4893/5290/5335/5291/6778/6776/5327/6774/6772/6714/5159/6654/2885/5296/3845/6777/3265/1399/5781/7057 21 Human_T.cell_leukemia_virus_1 R-HSA-171007 p38MAPK events 9/1332 13/10654 3.2453749436142003e-6 1.0715699945056862e-5 4.6714749153833364e-6 4893/9261/6714/1432/5603/3845/5600/3265/6300 9 Human_T.cell_leukemia_virus_1 R-HSA-5688426 Deubiquitination 65/1332 297/10654 3.286177530890831e-6 1.0822019198588129e-5 4.717824451898934e-6 5684/7186/6885/7419/7321/8027/2625/51720/63967/1080/3091/4287/7706/8517/580/29086/7316/10213/993/79155/890/4792/983/4092/8678/2099/4609/7415/4194/4089/8850/5688/5687/6502/7347/4088/5685/5683/5708/5686/2033/408/5728/7157/8900/4087/63891/7189/6233/672/7311/367/79184/7187/387/60/7040/5887/1540/9736/7874/10254/7314/4193/7528 65 Human_T.cell_leukemia_virus_1 R-HSA-1295596 Spry regulation of FGF signaling 10/1332 16/10654 3.5416217525909108e-6 1.157236406431004e-5 5.044934882022871e-6 5594/7316/6714/867/6233/2885/7311/5781/7314/5595 10 Human_T.cell_leukemia_virus_1 R-HSA-1433559 Regulation of KIT signaling 10/1332 16/10654 3.5416217525909108e-6 1.157236406431004e-5 5.044934882022871e-6 5777/5578/6714/8651/867/4067/2534/6654/2885/3932 10 Human_T.cell_leukemia_virus_1 R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 10/1332 16/10654 3.5416217525909108e-6 1.157236406431004e-5 5.044934882022871e-6 4790/5604/8517/7316/79155/6233/7311/3551/6416/7314 10 Human_T.cell_leukemia_virus_1 R-HSA-180024 DARPP-32 events 13/1332 26/10654 3.6980015449217197e-6 1.2052036123086848e-5 5.254046372795789e-6 5575/84152/5567/5532/5568/5573/5530/5566/5576/5499/5577/1020/5141 13 Human_T.cell_leukemia_virus_1 R-HSA-9013694 Signaling by NOTCH4 26/1332 82/10654 3.951797911044301e-6 1.2845896051921786e-5 5.600127054682662e-6 5684/207/55534/84441/10046/7316/10213/22938/8850/5688/1387/5687/4088/5685/5683/5708/5686/2033/55294/4853/9794/6233/7311/3516/4851/7314 26 Human_T.cell_leukemia_virus_1 R-HSA-1500620 Meiosis 33/1332 118/10654 4.764182997299822e-6 1.5446758274750452e-5 6.733964572960412e-6 1017/7014/6118/1019/5888/4438/10111/675/10274/7013/4292/545/472/23626/10735/5885/641/6119/4683/4439/5889/8243/9126/7329/6847/29893/672/27030/5932/11144/7156/6117/84057 33 Human_T.cell_leukemia_virus_1 R-HSA-5689896 Ovarian tumor domain proteases 16/1332 38/10654 4.868322145108236e-6 1.5743828428139234e-5 6.863471350565259e-6 7321/7706/8517/7316/79155/983/2099/7415/5728/7157/7189/6233/7311/7187/387/7314 16 Human_T.cell_leukemia_virus_1 R-HSA-9020702 Interleukin-1 signaling 30/1332 103/10654 5.210704904856568e-6 1.6807863513614265e-5 7.327334022753771e-6 5684/351/4790/6885/5604/3553/8878/8517/7316/10213/79155/5970/4792/3146/3552/5688/5687/5685/5683/5708/5686/57162/7189/6285/6233/7311/7334/3551/6416/7314 30 Human_T.cell_leukemia_virus_1 R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 8/1332 11/10654 6.807996634405587e-6 2.1792518488758852e-5 9.500378322017706e-6 7422/3091/1387/2033/2056/2034/405/768 8 Human_T.cell_leukemia_virus_1 R-HSA-5655291 Signaling by FGFR4 in disease 8/1332 11/10654 6.807996634405587e-6 2.1792518488758852e-5 9.500378322017706e-6 5295/4893/5290/5335/6654/2885/3845/3265 8 Human_T.cell_leukemia_virus_1 R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 8/1332 11/10654 6.807996634405587e-6 2.1792518488758852e-5 9.500378322017706e-6 627/4893/4915/6654/2885/3845/3265/5781 8 Human_T.cell_leukemia_virus_1 R-HSA-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle 15/1332 35/10654 7.414124731001561e-6 2.367250992791869e-5 1.0319954541415478e-5 7841/9695/821/811/56886/7316/5589/7415/80267/2923/6233/7311/23193/5887/7314 15 Human_T.cell_leukemia_virus_1 R-HSA-1234174 Cellular response to hypoxia 24/1332 75/10654 7.723998733183907e-6 2.4599469383152798e-5 1.0724059533614432e-5 5684/112399/7321/7422/3091/7316/10213/5688/1387/5687/5685/5683/5708/5686/2033/7428/6233/2056/7311/2034/55662/405/768/7314 24 Human_T.cell_leukemia_virus_1 R-HSA-198323 AKT phosphorylates targets in the cytosol 9/1332 14/10654 8.075592860661627e-6 2.5654282370485676e-5 1.1183901861788167e-5 842/207/1027/1026/2932/10000/208/2931/4193 9 Human_T.cell_leukemia_virus_1 R-HSA-202733 Cell surface interactions at the vascular wall 36/1332 137/10654 8.533150155801375e-6 2.703955389420184e-5 1.1787806525712626e-5 5295/3675/5777/3635/4893/6464/5290/5335/960/5291/3684/4312/6383/338/6714/914/972/4067/140885/682/2335/2534/83692/6402/6654/2885/3932/5296/7040/3687/3845/3265/5781/8795/2207/9046 36 Human_T.cell_leukemia_virus_1 R-HSA-933542 TRAF6 mediated NF-kB activation 12/1332 24/10654 8.83122390056259e-6 2.7913768007305872e-5 1.2168917355707774e-5 351/7186/4790/4214/7706/8517/5970/4792/3146/7189/6285/3551 12 Human_T.cell_leukemia_virus_1 R-HSA-447115 Interleukin-12 family signaling 20/1332 57/10654 9.323884674914779e-6 2.9397110077801485e-5 1.281557555897797e-5 9049/6775/3595/821/4478/6175/6774/6772/149233/6950/3717/9466/3458/6648/3716/3594/2939/3586/5034/3572 20 Human_T.cell_leukemia_virus_1 R-HSA-2428924 IGF1R signaling cascade 19/1332 53/10654 1.0883512496351025e-5 3.422864680102397e-5 1.4921868448944433e-5 5295/54106/4893/6464/5290/3667/5291/2263/2261/208/6654/2885/8660/9846/3479/5296/3845/3265/5781 19 Human_T.cell_leukemia_virus_1 R-HSA-1989781 PPARA activates gene expression 32/1332 117/10654 1.0970697050188091e-5 3.441680022228583e-5 1.5003893327596787e-5 8841/1374/5468/6721/51/6720/5465/406/335/9611/5469/2874/4800/9612/1024/6667/336/1387/6604/2033/2101/4801/4199/2168/10498/2274/23054/405/8202/8648/10891/10062 32 Human_T.cell_leukemia_virus_1 R-HSA-2173789 TGF-beta receptor signaling activates SMADs 14/1332 32/10654 1.1208068467448657e-5 3.5074005303607986e-5 1.529039976837065e-5 7316/5501/4092/4089/867/4088/9040/4087/5499/6233/7514/7311/7040/7314 14 Human_T.cell_leukemia_virus_1 R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 15/1332 36/10654 1.1249757043731585e-5 3.511710759556907e-5 1.5309190073877907e-5 4893/5604/5594/6714/5605/2244/2335/408/1445/8826/7450/60/3845/3265/5595 15 Human_T.cell_leukemia_virus_1 R-HSA-1169408 ISG15 antiviral mechanism 23/1332 72/10654 1.2283283734918157e-5 3.8248442917146146e-5 1.66742856328618e-5 3838/5335/25820/1982/7706/7316/4734/6772/8672/1981/1973/3661/7324/1977/6233/3716/7311/5610/5300/7334/1974/7314/5595 23 Human_T.cell_leukemia_virus_1 R-HSA-73884 Base Excision Repair 27/1332 92/10654 1.3068705623651629e-5 4.059365845568827e-5 1.769667480161793e-5 11284/7014/6118/2237/328/57804/7515/5982/54107/7013/3978/5425/5111/5426/6119/5427/5985/142/5984/3980/5983/6117/5981/10038/10714/5424/56655 27 Human_T.cell_leukemia_virus_1 R-HSA-2467813 Separation of Sister Chromatids 45/1332 190/10654 1.3296419064495581e-5 4.119924921954542e-5 1.796068014675187e-5 5905/5684/11065/246184/55869/7321/8697/9212/10274/23244/10735/6232/8881/5885/7316/10213/5501/51433/5688/699/5687/5685/5683/5708/5686/119504/8243/9126/51529/7324/64682/29945/10393/6233/5527/51434/7514/7311/25906/5347/57551/84790/29882/7314/996 45 Human_T.cell_leukemia_virus_1 R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 19/1332 54/10654 1.484379583193948e-5 4.5880823480540215e-5 2.0001597383784998e-5 5295/54106/4893/6464/5290/3667/5291/2263/2261/208/6654/2885/8660/9846/3479/5296/3845/3265/5781 19 Human_T.cell_leukemia_virus_1 R-HSA-8854691 Interleukin-20 family signaling 12/1332 25/10654 1.5056275432905992e-5 4.642351591812681e-5 2.0238182405944327e-5 6775/11009/6776/6774/3718/6772/3717/58985/3716/3588/6777/5781 12 Human_T.cell_leukemia_virus_1 R-HSA-1368082 RORA activates gene expression 10/1332 18/10654 1.5254931160769085e-5 4.6806593659140264e-5 2.0405183914661602e-5 1374/6720/5465/5469/1387/6604/2033/10498/23054/8648 10 Human_T.cell_leukemia_virus_1 R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 10/1332 18/10654 1.5254931160769085e-5 4.6806593659140264e-5 2.0405183914661602e-5 5295/5290/6776/6774/6772/11064/2885/9846/6777/7750 10 Human_T.cell_leukemia_virus_1 R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 32/1332 119/10654 1.602590576140705e-5 4.905252907019481e-5 2.1384292231253872e-5 8841/1374/5468/6721/51/6720/5465/406/335/9611/5469/2874/4800/9612/1024/6667/336/1387/6604/2033/2101/4801/4199/2168/10498/2274/23054/405/8202/8648/10891/10062 32 Human_T.cell_leukemia_virus_1 R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 13/1332 29/10654 1.677938796657434e-5 5.123415063580224e-5 2.2335363133840654e-5 5434/5440/5430/5436/5441/5438/5431/5435/5433/5437/3320/5439/5432 13 Human_T.cell_leukemia_virus_1 R-HSA-5654736 Signaling by FGFR1 18/1332 50/10654 1.7301854981807496e-5 5.27015340608083e-5 2.29750642169535e-5 5295/4893/6464/5290/5335/5594/7316/6714/867/6654/6233/2885/7311/3845/3265/5781/7314/5595 18 Human_T.cell_leukemia_virus_1 R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 9/1332 15/10654 1.79447025828394e-5 5.4265470791374916e-5 2.365685740298413e-5 8027/7316/867/6455/6233/2885/7311/10254/7314 9 Human_T.cell_leukemia_virus_1 R-HSA-937039 IRAK1 recruits IKK complex 9/1332 15/10654 1.79447025828394e-5 5.4265470791374916e-5 2.365685740298413e-5 8517/7316/57162/7189/6233/7311/7334/3551/7314 9 Human_T.cell_leukemia_virus_1 R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 9/1332 15/10654 1.79447025828394e-5 5.4265470791374916e-5 2.365685740298413e-5 8517/7316/57162/7189/6233/7311/7334/3551/7314 9 Human_T.cell_leukemia_virus_1 R-HSA-210990 PECAM1 interactions 8/1332 12/10654 1.817633847350665e-5 5.4834133812161544e-5 2.3904764217334255e-5 5777/3635/5335/6714/4067/2534/3932/5781 8 Human_T.cell_leukemia_virus_1 R-HSA-1250196 SHC1 events in ERBB2 signaling 11/1332 22/10654 2.1146527002049e-5 6.364194011621445e-5 2.774449903819574e-5 4893/6464/5578/2064/1950/6654/2885/1956/5581/3845/3265 11 Human_T.cell_leukemia_virus_1 R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 20/1332 60/10654 2.2293435856016902e-5 6.693351385887652e-5 2.917945002131593e-5 1017/1019/5684/1027/7316/10213/890/1026/5688/5687/6502/5685/5683/5708/5686/595/8900/6233/7311/7314 20 Human_T.cell_leukemia_virus_1 R-HSA-5655302 Signaling by FGFR1 in disease 15/1332 38/10654 2.4495193177458193e-5 7.336893575533907e-5 3.198495149237022e-5 5295/4893/5290/5335/6776/6774/6772/11064/6654/2885/9846/3845/6777/3265/7750 15 Human_T.cell_leukemia_virus_1 R-HSA-901042 Calnexin/calreticulin cycle 12/1332 26/10654 2.4791938765464047e-5 7.401466625068898e-5 3.226645562430672e-5 9695/821/811/56886/7316/5589/80267/2923/6233/7311/23193/7314 12 Human_T.cell_leukemia_virus_1 R-HSA-1592230 Mitochondrial biogenesis 27/1332 95/10654 2.4828449251026035e-5 7.401466625068898e-5 3.226645562430672e-5 8841/23410/200186/5465/4209/9611/5469/10989/54205/64784/1432/4208/1387/6604/2101/6648/10498/84808/1385/23054/1386/5600/6300/23373/8648/814/10891 27 Human_T.cell_leukemia_virus_1 R-HSA-68882 Mitotic Anaphase 46/1332 201/10654 2.729118181878173e-5 8.116384569273621e-5 3.538311740098366e-5 5905/5684/11065/246184/55869/7321/8697/9212/10274/23244/10735/6232/7443/8881/5885/7316/10213/5501/51433/5688/699/5687/5685/5683/5708/5686/119504/8243/9126/51529/7324/64682/29945/10393/6233/5527/51434/7514/7311/25906/5347/57551/84790/29882/7314/996 46 Human_T.cell_leukemia_virus_1 R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 10/1332 19/10654 2.8598983409626636e-5 8.485264417290167e-5 3.699123723042572e-5 7027/7153/4149/1869/993/5111/4609/5928/990/3065 10 Human_T.cell_leukemia_virus_1 R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 20/1332 61/10654 2.931707656900508e-5 8.677854664425504e-5 3.783082821659851e-5 25/51517/4771/5594/919/6850/10552/10094/10092/917/3320/695/2885/10096/3326/10097/7409/60/10095/5595 20 Human_T.cell_leukemia_virus_1 R-HSA-2555396 Mitotic Metaphase and Anaphase 46/1332 202/10654 3.115459169306248e-5 9.20011181921892e-5 4.010759148032012e-5 5905/5684/11065/246184/55869/7321/8697/9212/10274/23244/10735/6232/7443/8881/5885/7316/10213/5501/51433/5688/699/5687/5685/5683/5708/5686/119504/8243/9126/51529/7324/64682/29945/10393/6233/5527/51434/7514/7311/25906/5347/57551/84790/29882/7314/996 46 Human_T.cell_leukemia_virus_1 R-HSA-111885 Opioid Signalling 26/1332 91/10654 3.155640302626298e-5 9.296944966519632e-5 4.0529732470560867e-5 818/815/3838/5575/84152/5567/817/5578/5532/5594/5568/5582/5573/5173/5530/5443/5566/4988/5576/816/5499/5577/1385/1020/5141/814 26 Human_T.cell_leukemia_virus_1 R-HSA-2428928 IRS-related events triggered by IGF1R 18/1332 52/10654 3.198290262615901e-5 9.400582127034587e-5 4.098153533750331e-5 5295/54106/4893/5290/3667/5291/2263/2261/208/6654/2885/8660/9846/3479/5296/3845/3265/5781 18 Human_T.cell_leukemia_virus_1 R-HSA-3214841 PKMTs methylate histone lysines 22/1332 71/10654 3.223380498200192e-5 9.430262015664748e-5 4.111092385709425e-5 9070/11091/4790/2146/8085/5929/5931/79813/5970/29072/2122/5928/23512/9757/80854/58508/8726/55729/64754/4297/10919/79723 22 Human_T.cell_leukemia_virus_1 R-HSA-4551638 SUMOylation of chromatin organization proteins 22/1332 71/10654 3.223380498200192e-5 9.430262015664748e-5 4.111092385709425e-5 1912/23468/83746/8535/6045/80012/6613/1911/7341/84733/23512/57332/3066/3065/23314/1107/7329/9063/648/6304/6015/8554 22 Human_T.cell_leukemia_virus_1 R-HSA-112399 IRS-mediated signalling 17/1332 48/10654 3.769402944020838e-5 1.1002108825007456e-4 4.7963339451333654e-5 5295/54106/4893/5290/3667/5291/2263/2261/208/6654/2885/8660/9846/5296/3845/3265/5781 17 Human_T.cell_leukemia_virus_1 R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 7/1332 10/10654 4.001369466351095e-5 1.1633172450061031e-4 5.071444102151951e-5 2308/2309/23410/8850/1387/2033/23411 7 Human_T.cell_leukemia_virus_1 R-HSA-1169091 Activation of NF-kappaB in B cells 21/1332 67/10654 4.004104666833407e-5 1.1633172450061031e-4 5.071444102151951e-5 5684/4790/6885/5579/5966/8517/7316/10213/5970/4792/8915/5688/5687/5685/5683/5708/5686/6233/7311/3551/7314 21 Human_T.cell_leukemia_virus_1 R-HSA-157579 Telomere Maintenance 24/1332 82/10654 4.0918618644252285e-5 1.1860742454946862e-4 5.170652513620044e-5 7014/6118/2237/7015/1763/57804/5982/54107/7013/3978/5425/5111/5426/6119/1736/5427/5985/5984/5983/6117/5981/10714/5424/56655 24 Human_T.cell_leukemia_virus_1 R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 8/1332 13/10654 4.206588012133461e-5 1.2137357154274986e-4 5.291241801838564e-5 207/2064/7316/10000/208/6233/7311/7314 8 Human_T.cell_leukemia_virus_1 R-HSA-209543 p75NTR recruits signalling complexes 8/1332 13/10654 4.206588012133461e-5 1.2137357154274986e-4 5.291241801838564e-5 8878/7316/4803/7189/6233/7311/3551/7314 8 Human_T.cell_leukemia_virus_1 R-HSA-1912408 Pre-NOTCH Transcription and Translation 26/1332 93/10654 4.76034368537153e-5 1.3703689602282345e-4 5.974079393179736e-5 1999/3725/7027/55534/57690/27327/84441/51548/10046/192670/1869/22938/8850/1387/2033/595/4853/192669/7157/861/23112/9794/4343/26523/3516/4851 26 Human_T.cell_leukemia_virus_1 R-HSA-5674135 MAP2K and MAPK activation 15/1332 40/10654 4.9922712080729574e-5 1.4305870568919772e-4 6.236598248186095e-5 4893/5604/5594/6714/5605/2244/2335/408/1445/8826/7450/60/3845/3265/5595 15 Human_T.cell_leukemia_virus_1 R-HSA-5675221 Negative regulation of MAPK pathway 15/1332 40/10654 4.9922712080729574e-5 1.4305870568919772e-4 6.236598248186095e-5 4893/5604/5594/7316/5605/1847/6233/5527/7311/5536/1843/3845/3265/7314/5595 15 Human_T.cell_leukemia_virus_1 R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 17/1332 49/10654 5.106641526264276e-5 1.4567244988753877e-4 6.350543585591807e-5 1017/7027/7832/1027/1869/891/890/983/1026/5111/1647/2033/995/7157/8900/10498/1263 17 Human_T.cell_leukemia_virus_1 R-HSA-9012852 Signaling by NOTCH3 17/1332 49/10654 5.106641526264276e-5 1.4567244988753877e-4 6.350543585591807e-5 55534/84441/10046/7316/1950/6772/22938/8850/1387/2033/9794/6233/7311/1956/3516/4851/7314 17 Human_T.cell_leukemia_virus_1 R-HSA-8939902 Regulation of RUNX2 expression and activity 22/1332 73/10654 5.187066119159899e-5 1.4763188185301253e-4 6.435964391717808e-5 5684/7316/10213/865/6772/2099/2932/5688/5687/6502/2908/5685/5683/5708/5686/2101/55294/6233/7311/860/10891/7314 22 Human_T.cell_leukemia_virus_1 R-HSA-73886 Chromosome Maintenance 29/1332 110/10654 5.8564318670202047e-005 1.6630680109958051e-4 7.250091487982717e-5 8467/7014/6118/2237/7015/1763/57804/5982/5931/54107/7013/3978/5425/5111/5426/6119/5928/1736/5427/5985/5984/51773/11339/5983/6117/5981/10714/5424/56655 29 Human_T.cell_leukemia_virus_1 R-HSA-3371571 HSF1-dependent transactivation 11/1332 24/10654 5.892380360443114e-5 1.665756065940997e-4 7.261809977033383e-5 818/815/817/1387/3320/2033/816/3326/2475/3312/10728 11 Human_T.cell_leukemia_virus_1 R-HSA-450302 activated TAK1 mediates p38 MAPK activation 11/1332 24/10654 5.892380360443114e-5 1.665756065940997e-4 7.261809977033383e-5 6885/8517/7316/9261/1432/7189/6233/7311/5600/7334/7314 11 Human_T.cell_leukemia_virus_1 R-HSA-5673000 RAF activation 13/1332 32/10654 5.977869156735853e-5 1.6861343944335656e-4 7.35064864446396e-5 818/815/4893/5604/817/6714/5605/3717/816/5527/3845/3265/5245 13 Human_T.cell_leukemia_virus_1 R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 12/1332 28/10654 6.141333582621124e-5 1.7283663639680927e-4 7.534757556918889e-5 10694/5204/10575/5203/7203/10576/908/6950/10574/60/84790/22948 12 Human_T.cell_leukemia_virus_1 R-HSA-76002 Platelet activation, signaling and aggregation 55/1332 262/10654 6.285736289495e-5 1.7650571991483728e-4 7.694710072431614e-5 5295/5777/5590/351/6464/5290/7018/5579/2153/5291/7042/3937/207/813/7422/5578/5594/5582/2157/334/6810/1950/335/6850/2767/6714/8503/1432/4067/5588/2244/3309/9948/2335/2534/408/1445/6654/2885/7409/7873/3932/3479/7450/387/5296/5581/29789/7040/213/5781/7057/7043/2207/5595 55 Human_T.cell_leukemia_virus_1 R-HSA-6806834 Signaling by MET 23/1332 79/10654 6.443927748271732e-5 1.805447908090387e-4 7.870792068572435e-5 5295/3675/4893/6464/5290/8027/10048/7316/6774/6714/867/6455/2335/6654/6233/2885/7311/3845/3265/1399/5781/10254/7314 23 Human_T.cell_leukemia_virus_1 R-HSA-8941858 Regulation of RUNX3 expression and activity 18/1332 55/10654 7.472245928523108e-5 2.0889078617960158e-4 9.10652661698372e-5 5684/1029/7316/10213/865/6714/5688/5687/5685/5683/5708/5686/2033/6233/7311/7040/7314/4193 18 Human_T.cell_leukemia_virus_1 R-HSA-5250913 Positive epigenetic regulation of rRNA expression 28/1332 106/10654 7.52123289027166e-5 2.0979403494371949e-4 9.145903456252855e-5 8467/5434/5440/9112/9219/5931/5441/11335/5435/9031/1108/8850/5928/2932/5437/57459/54815/2033/3066/3065/1107/57504/84172/6908/60/53615/10919/9188 28 Human_T.cell_leukemia_virus_1 R-HSA-983169 Class I MHC mediated antigen processing & presentation 72/1332 371/10654 7.647252189077526e-5 2.1283724012963556e-4 9.278571007241248e-5 3135/5684/6737/11065/84708/246184/54850/3107/7321/9021/8697/6890/821/811/81559/6892/7099/8517/7336/6810/9690/9554/8881/6891/54778/7316/10213/4008/567/4734/7337/8651/3106/51433/5688/5687/6502/5685/5683/3309/5708/5686/55294/2923/7428/83737/51529/9040/695/7324/63891/10075/64682/29945/10393/80176/8924/6233/51434/51343/7311/6047/3133/3134/29882/7334/4591/3551/3105/9820/7314/996 72 Human_T.cell_leukemia_virus_1 R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 23/1332 80/10654 7.99060119909533e-5 2.2190234676516392e-4 9.67376141449673e-5 3838/5335/25820/1982/7706/7316/4734/6772/8672/1981/1973/3661/7324/1977/6233/3716/7311/5610/5300/7334/1974/7314/5595 23 Human_T.cell_leukemia_virus_1 R-HSA-453274 Mitotic G2-G2/M phases 44/1332 198/10654 8.49039745075471e-5 2.352625549129829e-4 1.0256195390315798e-4 1017/5684/994/902/7531/10142/54801/51400/7316/10213/80321/1869/891/993/890/4331/983/1026/5566/5928/5688/5687/5685/5683/5708/3320/5686/2033/995/11064/7157/8900/1069/5577/6233/3326/7514/7311/5347/84790/1453/7465/1022/7314 44 Human_T.cell_leukemia_virus_1 R-HSA-162594 Early Phase of HIV Life Cycle 8/1332 14/10654 8.738626313556497e-5 2.3909996604822882e-4 1.0423486094145026e-4 2237/3159/7518/7520/3978/3981/2547/1234 8 Human_T.cell_leukemia_virus_1 R-HSA-180336 SHC1 events in EGFR signaling 8/1332 14/10654 8.738626313556497e-5 2.3909996604822882e-4 1.0423486094145026e-4 4893/6464/1950/6654/2885/1956/3845/3265 8 Human_T.cell_leukemia_virus_1 R-HSA-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase 8/1332 14/10654 8.738626313556497e-5 2.3909996604822882e-4 1.0423486094145026e-4 5575/5567/5568/5573/5566/5576/5577/1385 8 Human_T.cell_leukemia_virus_1 R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 8/1332 14/10654 8.738626313556497e-5 2.3909996604822882e-4 1.0423486094145026e-4 8841/9611/2874/9612/5566/3065/4204/814 8 Human_T.cell_leukemia_virus_1 R-HSA-9005895 Pervasive developmental disorders 8/1332 14/10654 8.738626313556497e-5 2.3909996604822882e-4 1.0423486094145026e-4 8841/9611/2874/9612/5566/3065/4204/814 8 Human_T.cell_leukemia_virus_1 R-HSA-1980145 Signaling by NOTCH2 13/1332 33/10654 8.742924036739686e-5 2.3909996604822882e-4 1.0423486094145026e-4 55534/84441/10046/7316/2033/3002/4853/9794/6233/1385/7311/3516/7314 13 Human_T.cell_leukemia_virus_1 R-HSA-5654708 Downstream signaling of activated FGFR3 11/1332 25/10654 9.339114716777279e-5 2.542988379590004e-4 1.1086076025155987e-4 5295/4893/6464/5290/5335/2261/6654/2885/3845/3265/5781 11 Human_T.cell_leukemia_virus_1 R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 11/1332 25/10654 9.339114716777279e-5 2.542988379590004e-4 1.1086076025155987e-4 55534/84441/10046/6772/22938/8850/1387/2033/9794/3516/4851 11 Human_T.cell_leukemia_virus_1 R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 27/1332 102/10654 9.660289894499258e-5 2.62476127155077e-4 1.1442562316776433e-4 7124/5684/7186/356/7316/10213/970/3604/7292/7133/5688/5687/5685/5683/5708/5686/9040/4049/6233/7311/7293/7187/958/8784/939/959/7314 27 Human_T.cell_leukemia_virus_1 R-HSA-1236977 Endosomal/Vacuolar pathway 7/1332 11/10654 9.812366621444544e-5 2.648917856175373e-4 1.1547872170256623e-4 3135/3107/567/3106/3133/3134/3105 7 Human_T.cell_leukemia_virus_1 R-HSA-8851805 MET activates RAS signaling 7/1332 11/10654 9.812366621444544e-5 2.648917856175373e-4 1.1547872170256623e-4 4893/6464/10048/6654/2885/3845/3265 7 Human_T.cell_leukemia_virus_1 R-HSA-9020956 Interleukin-27 signaling 7/1332 11/10654 9.812366621444544e-5 2.648917856175373e-4 1.1547872170256623e-4 821/6774/6772/3717/9466/3716/3572 7 Human_T.cell_leukemia_virus_1 R-HSA-68949 Orc1 removal from chromatin 21/1332 71/10654 1.0309574334773074e-4 2.77718297926007e-4 1.2107039847665437e-4 1017/4172/5684/23594/7316/10213/890/4171/5688/5687/6502/5685/5683/5708/5686/990/81620/8900/6233/7311/7314 21 Human_T.cell_leukemia_virus_1 R-HSA-5696394 DNA Damage Recognition in GG-NER 14/1332 38/10654 1.1104217427088688e-4 2.97848731839607e-4 1.2984619637556292e-4 9318/7316/10980/142/10987/1069/6233/7311/60/5887/10038/7508/7314/7528 14 Human_T.cell_leukemia_virus_1 R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 14/1332 38/10654 1.1104217427088688e-4 2.97848731839607e-4 1.2984619637556292e-4 7020/7422/51741/2064/348/1026/2099/4609/7341/1387/2033/7329/1956/7528 14 Human_T.cell_leukemia_virus_1 R-HSA-5675482 Regulation of necroptotic cell death 9/1332 18/10654 1.2253183193087458e-4 3.265784842564411e-4 1.4237083950933464e-4 7186/356/355/841/7316/6233/7311/8795/7314 9 Human_T.cell_leukemia_virus_1 R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 9/1332 18/10654 1.2253183193087458e-4 3.265784842564411e-4 1.4237083950933464e-4 7027/891/983/5111/1647/2033/995/7157/10498 9 Human_T.cell_leukemia_virus_1 R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 9/1332 18/10654 1.2253183193087458e-4 3.265784842564411e-4 1.4237083950933464e-4 3665/7099/7316/3661/6233/7311/7187/5781/7314 9 Human_T.cell_leukemia_virus_1 R-HSA-69541 Stabilization of p53 18/1332 57/10654 1.259478888850747e-4 3.349734550051247e-4 1.4603059999805036e-4 5684/1029/11200/472/7316/10213/4194/5688/5687/5685/5683/5708/5686/7157/6233/7311/7314/4193 18 Human_T.cell_leukemia_virus_1 R-HSA-114452 Activation of BH3-only proteins 12/1332 30/10654 1.3737362256517963e-4 3.645907535590632e-4 1.58942166014787e-4 596/10018/7531/7027/207/1869/10000/7157/208/7161/5599/637 12 Human_T.cell_leukemia_virus_1 R-HSA-69275 G2/M Transition 43/1332 196/10654 1.3839092158784888e-4 3.66517430226345e-4 1.5978209450918398e-4 1017/5684/994/902/7531/10142/54801/51400/7316/10213/80321/891/993/890/4331/983/1026/5566/5928/5688/5687/5685/5683/5708/3320/5686/2033/995/11064/7157/8900/1069/5577/6233/3326/7514/7311/5347/84790/1453/7465/1022/7314 43 Human_T.cell_leukemia_virus_1 R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 24/1332 88/10654 1.4054400576546985e-4 3.7143772952302745e-4 1.6192708315747412e-4 5684/207/5578/3315/26986/7316/10213/9261/1432/5688/5687/5685/5683/5708/5686/1981/6233/7514/7311/5600/3312/8570/7314/1994 24 Human_T.cell_leukemia_virus_1 R-HSA-2173788 Downregulation of TGF-beta receptor signaling 11/1332 26/10654 1.4369723332946613e-4 3.7897509335108677e-4 1.6521297266832585e-4 7316/5501/4092/4088/4087/5499/6233/7514/7311/7040/7314 11 Human_T.cell_leukemia_virus_1 R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 8/1332 15/10654 1.667480466243945e-4 4.3884736956796707e-4 1.9131409885776157e-4 54106/3665/7316/7189/6233/7311/7334/7314 8 Human_T.cell_leukemia_virus_1 R-HSA-112043 PLC beta mediated events 17/1332 54/10654 2.0106434307586845e-4 5.280562496648069e-4 2.302044231238929e-4 818/815/3838/5575/5567/817/5578/5594/5568/5582/5573/5566/5576/816/5577/1385/814 17 Human_T.cell_leukemia_virus_1 R-HSA-3858494 Beta-catenin independent WNT signaling 34/1332 146/10654 2.064639680002735e-4 5.411076494673834e-4 2.3589413887750544e-4 815/5684/6885/5579/1499/4772/5578/5532/57690/5582/27327/192670/5530/7316/10213/6934/5688/5687/5685/5683/5708/5686/192669/23112/6233/1855/1857/7311/387/4343/3845/26523/7314/5592 34 Human_T.cell_leukemia_virus_1 R-HSA-111932 CaMK IV-mediated phosphorylation of CREB 7/1332 12/10654 2.1004992505175958e-4 5.448305272476568e-4 2.3751711546818612e-4 818/815/3838/817/816/1385/814 7 Human_T.cell_leukemia_virus_1 R-HSA-170968 Frs2-mediated activation 7/1332 12/10654 2.1004992505175958e-4 5.448305272476568e-4 2.3751711546818612e-4 5604/5594/5605/4914/4803/1399/5595 7 Human_T.cell_leukemia_virus_1 R-HSA-389359 CD28 dependent Vav1 pathway 7/1332 12/10654 2.1004992505175958e-4 5.448305272476568e-4 2.3751711546818612e-4 941/2534/942/2885/7409/3932/940 7 Human_T.cell_leukemia_virus_1 R-HSA-5689877 Josephin domain DUBs 7/1332 12/10654 2.1004992505175958e-4 5.448305272476568e-4 2.3751711546818612e-4 4287/7316/7415/6233/7311/5887/7314 7 Human_T.cell_leukemia_virus_1 R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 7/1332 12/10654 2.1004992505175958e-4 5.448305272476568e-4 2.3751711546818612e-4 3665/7316/3661/6233/7311/7187/7314 7 Human_T.cell_leukemia_virus_1 R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress 11/1332 27/10654 2.1528388734232462e-4 5.572574697050296e-4 2.4293460105122625e-4 1051/1649/3576/468/4800/1054/4801/22926/6347/467/8570 11 Human_T.cell_leukemia_virus_1 R-HSA-5620922 BBSome-mediated cargo-targeting to cilium 10/1332 23/10654 2.2059267870202525e-4 5.698266731152932e-4 2.484141048389823e-4 10694/79738/6608/10575/7203/10576/6950/55212/117177/22948 10 Human_T.cell_leukemia_virus_1 R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 13/1332 36/10654 2.456367644234144e-4 6.332193640259331e-4 2.7604994448791827e-4 25/51517/5594/10552/10094/10092/695/2885/10096/10097/60/10095/5595 13 Human_T.cell_leukemia_virus_1 R-HSA-112040 G-protein mediated events 17/1332 55/10654 2.5758571214010205e-4 6.6266426558742e-4 2.888863545904492e-4 818/815/3838/5575/5567/817/5578/5594/5568/5582/5573/5566/5576/816/5577/1385/814 17 Human_T.cell_leukemia_virus_1 R-HSA-912446 Meiotic recombination 23/1332 86/10654 2.632538714903825e-4 6.75864021091635e-4 2.9464074553488566e-4 1017/6118/1019/5888/4438/10111/675/4292/472/23626/641/6119/4683/4439/5889/29893/672/27030/5932/11144/7156/6117/84057 23 Human_T.cell_leukemia_virus_1 R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 12/1332 32/10654 2.822818198658447e-4 7.232393673955858e-4 3.152938753352023e-4 10694/5204/10575/5203/7203/10576/908/6950/10574/60/84790/22948 12 Human_T.cell_leukemia_virus_1 R-HSA-1963640 GRB2 events in ERBB2 signaling 8/1332 16/10654 2.9703314388420125e-4 7.564123380694842e-4 3.297555251729573e-4 4893/2064/1950/6654/2885/1956/3845/3265 8 Human_T.cell_leukemia_virus_1 R-HSA-205043 NRIF signals cell death from the nucleus 8/1332 16/10654 2.9703314388420125e-4 7.564123380694842e-4 3.297555251729573e-4 8878/7316/4803/7189/6233/7311/5599/7314 8 Human_T.cell_leukemia_virus_1 R-HSA-2559584 Formation of Senescence-Associated Heterochromatin Foci (SAHF) 8/1332 16/10654 2.9703314388420125e-4 7.564123380694842e-4 3.297555251729573e-4 3159/7290/5925/29855/25842/7157/8091/57634 8 Human_T.cell_leukemia_virus_1 R-HSA-69205 G1/S-Specific Transcription 11/1332 28/10654 3.14847185382163e-4 8.001570893146687e-4 3.4882590873813274e-4 8318/7027/1869/1876/983/5111/5928/990/81620/3065/8900 11 Human_T.cell_leukemia_virus_1 R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 9/1332 20/10654 3.3492894931073475e-4 8.455532437182535e-4 3.6861621619714677e-4 7321/8517/7316/7189/6233/7311/7334/3551/7314 9 Human_T.cell_leukemia_virus_1 R-HSA-5213460 RIPK1-mediated regulated necrosis 9/1332 20/10654 3.3492894931073475e-4 8.455532437182535e-4 3.6861621619714677e-4 7186/356/355/841/7316/6233/7311/8795/7314 9 Human_T.cell_leukemia_virus_1 R-HSA-5218859 Regulated Necrosis 9/1332 20/10654 3.3492894931073475e-4 8.455532437182535e-4 3.6861621619714677e-4 7186/356/355/841/7316/6233/7311/8795/7314 9 Human_T.cell_leukemia_virus_1 R-HSA-5689901 Metalloprotease DUBs 13/1332 37/10654 3.358136044391531e-4 8.455532437182535e-4 3.6861621619714677e-4 8027/51720/580/29086/7316/10213/8850/2033/6233/672/7311/79184/7314 13 Human_T.cell_leukemia_virus_1 R-HSA-6783589 Interleukin-6 family signaling 10/1332 24/10654 3.3607044662887657e-4 8.455532437182535e-4 3.6861621619714677e-4 9021/6774/6772/867/3717/3716/3570/5781/3569/3572 10 Human_T.cell_leukemia_virus_1 R-HSA-1474165 Reproduction 33/1332 144/10654 3.480944976755243e-4 8.740576408698794e-4 3.8104261642808734e-4 1017/7014/6118/1019/5888/4438/10111/675/10274/7013/4292/545/472/23626/10735/5885/641/6119/4683/4439/5889/8243/9126/7329/6847/29893/672/27030/5932/11144/7156/6117/84057 33 Human_T.cell_leukemia_virus_1 R-HSA-3928662 EPHB-mediated forward signaling 14/1332 42/10654 3.744153360210582e-4 9.382758819013769e-4 4.090383519961656e-4 2904/6383/10552/10094/6714/10092/4067/2534/10096/10097/387/60/10095/3265 14 Human_T.cell_leukemia_virus_1 R-HSA-179812 GRB2 events in EGFR signaling 7/1332 13/10654 4.06031310803923e-4 0.0010114601762204656 4.4094280964845e-4 4893/1950/6654/2885/1956/3845/3265 7 Human_T.cell_leukemia_virus_1 R-HSA-68884 Mitotic Telophase/Cytokinesis 7/1332 13/10654 4.06031310803923e-4 0.0010114601762204656 4.4094280964845e-4 10274/23244/10735/5885/8243/9126/5347 7 Human_T.cell_leukemia_virus_1 R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 7/1332 13/10654 4.06031310803923e-4 0.0010114601762204656 4.4094280964845e-4 7531/11200/891/983/995/1111/7465 7 Human_T.cell_leukemia_virus_1 R-HSA-72165 mRNA Splicing - Minor Pathway 16/1332 52/10654 4.1101131418915383e-4 0.001021842358201493 4.454688884804435e-4 2963/5434/5440/5430/5436/5441/5438/5431/5435/10594/5433/9343/2962/5437/5439/5432 16 Human_T.cell_leukemia_virus_1 R-HSA-74752 Signaling by Insulin receptor 21/1332 78/10654 4.3501791356109954e-4 0.0010793935606703416 4.705581500370245e-4 5295/54106/4893/6464/5290/3667/5291/5594/2263/2261/3630/208/6654/2885/8660/9846/5296/3845/3265/5781/5595 21 Human_T.cell_leukemia_virus_1 R-HSA-5654732 Negative regulation of FGFR3 signaling 11/1332 29/10654 4.504695669164476e-4 0.0011133412871923204 4.853575521941251e-4 5594/7316/6714/2261/867/6233/2885/7311/5781/7314/5595 11 Human_T.cell_leukemia_virus_1 R-HSA-8863795 Downregulation of ERBB2 signaling 11/1332 29/10654 4.504695669164476e-4 0.0011133412871923204 4.853575521941251e-4 207/2064/7316/1950/10000/3320/208/6233/7311/1956/7314 11 Human_T.cell_leukemia_virus_1 R-HSA-68867 Assembly of the pre-replicative complex 19/1332 68/10654 4.851151516332097e-4 0.001196617374028584 5.216614943259077e-4 4172/5684/23594/7316/10213/1869/4171/51053/5688/5687/5685/5683/5708/5686/990/81620/6233/7311/7314 19 Human_T.cell_leukemia_virus_1 R-HSA-168325 Viral Messenger RNA Synthesis 14/1332 43/10654 4.921189255831059e-4 0.001211517824625337 5.28157297824283e-4 2963/5434/5440/5430/5436/5441/5438/5431/5435/5433/2962/5437/5439/5432 14 Human_T.cell_leukemia_virus_1 R-HSA-2029485 Role of phospholipids in phagocytosis 10/1332 25/10654 4.97856646269611e-4 0.0012208648362712878 5.322320974791574e-4 5295/5290/23646/5335/5291/919/6850/917/5296/5581 10 Human_T.cell_leukemia_virus_1 R-HSA-937041 IKK complex recruitment mediated by RIP1 10/1332 25/10654 4.97856646269611e-4 0.0012208648362712878 5.322320974791574e-4 7321/7099/8517/7316/7189/6233/7311/7334/3551/7314 10 Human_T.cell_leukemia_virus_1 R-HSA-180292 GAB1 signalosome 8/1332 17/10654 4.998240437405392e-4 0.001220929411700191 5.32260248929629e-4 5295/5290/1950/6714/1445/2885/1956/5781 8 Human_T.cell_leukemia_virus_1 R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 8/1332 17/10654 4.998240437405392e-4 0.001220929411700191 5.32260248929629e-4 2308/2309/1027/1026/4089/1647/4088/4087 8 Human_T.cell_leukemia_virus_1 R-HSA-2470946 Cohesin Loading onto Chromatin 6/1332 10/10654 5.064711133574354e-4 0.001232380388014804 5.372522652127127e-4 10274/23244/10735/5885/8243/9126 6 Human_T.cell_leukemia_virus_1 R-HSA-937042 IRAK2 mediated activation of TAK1 complex 6/1332 10/10654 5.064711133574354e-4 0.001232380388014804 5.372522652127127e-4 6885/7316/7189/6233/7311/7314 6 Human_T.cell_leukemia_virus_1 R-HSA-5218921 VEGFR2 mediated cell proliferation 9/1332 21/10654 5.215131262589936e-4 0.0012640915468859614 5.510766428981558e-4 5590/4893/5335/5579/7422/5578/6714/3845/3265 9 Human_T.cell_leukemia_virus_1 R-HSA-6807004 Negative regulation of MET activity 9/1332 21/10654 5.215131262589936e-4 0.0012640915468859614 5.510766428981558e-4 8027/7316/867/6455/6233/2885/7311/10254/7314 9 Human_T.cell_leukemia_virus_1 R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 13/1332 39/10654 6.022964803768893e-4 0.0014570941775271667 6.352155187780554e-4 10694/8841/10575/10528/7203/10576/908/6774/6950/55294/7157/10574/22948 13 Human_T.cell_leukemia_virus_1 R-HSA-5654696 Downstream signaling of activated FGFR2 11/1332 30/10654 6.317356399619194e-4 0.0015253808734589148 6.649848841704415e-4 5295/4893/6464/5290/5335/2263/6654/2885/3845/3265/5781 11 Human_T.cell_leukemia_virus_1 R-HSA-380108 Chemokine receptors bind chemokines 17/1332 59/10654 6.433983202175475e-4 0.0015476005484391486 6.746714799906254e-4 729230/6351/2919/3576/2920/2921/1236/6352/6348/3627/9034/4283/2833/6347/6356/1232/1234 17 Human_T.cell_leukemia_virus_1 R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 17/1332 59/10654 6.433983202175475e-4 0.0015476005484391486 6.746714799906254e-4 7321/79577/7336/5591/7316/56254/8915/5111/7415/9810/7324/5830/6233/7311/7334/3105/7314 17 Human_T.cell_leukemia_virus_1 R-HSA-5628897 TP53 Regulates Metabolic Genes 22/1332 86/10654 6.910445924211677e-4 0.001659034536766849 7.232507686850712e-4 7531/207/1345/57690/27327/192670/54205/1350/10000/5728/6009/192669/7157/23112/208/2475/4513/4343/50484/1327/4697/26523 22 Human_T.cell_leukemia_virus_1 R-HSA-912694 Regulation of IFNA signaling 10/1332 26/10654 7.19206279357205e-4 0.0017233324365938088 7.512812312487443e-4 5777/3455/9021/6772/8651/3454/3439/3716/3456/5781 10 Human_T.cell_leukemia_virus_1 R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 7/1332 14/10654 7.246763584722773e-4 0.0017233324365938088 7.512812312487443e-4 5594/5861/891/983/8548/5347/5595 7 Human_T.cell_leukemia_virus_1 R-HSA-169893 Prolonged ERK activation events 7/1332 14/10654 7.246763584722773e-4 0.0017233324365938088 7.512812312487443e-4 5604/5594/5605/4914/4803/1399/5595 7 Human_T.cell_leukemia_virus_1 R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 7/1332 14/10654 7.246763584722773e-4 0.0017233324365938088 7.512812312487443e-4 1017/1027/1869/890/1026/7157/8900 7 Human_T.cell_leukemia_virus_1 R-HSA-918233 TRAF3-dependent IRF activation pathway 7/1332 14/10654 7.246763584722773e-4 0.0017233324365938088 7.512812312487443e-4 3665/7706/1387/2033/3661/7187/3456 7 Human_T.cell_leukemia_virus_1 R-HSA-1912422 Pre-NOTCH Expression and Processing 26/1332 109/10654 7.540894351293009e-4 0.001789895300740869 7.802990977206867e-4 1999/3725/7027/55534/57690/27327/84441/51548/10046/192670/1869/22938/8850/1387/2033/595/4853/192669/7157/861/23112/9794/4343/26523/3516/4851 26 Human_T.cell_leukemia_virus_1 R-HSA-5655332 Signaling by FGFR3 in disease 9/1332 22/10654 7.854163045729071e-4 0.001857243817956235 8.096594671200724e-4 5295/4893/5290/5335/2261/6654/2885/3845/3265 9 Human_T.cell_leukemia_virus_1 R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 9/1332 22/10654 7.854163045729071e-4 0.001857243817956235 8.096594671200724e-4 5295/4893/5290/5335/2261/6654/2885/3845/3265 9 Human_T.cell_leukemia_virus_1 R-HSA-5610783 Degradation of GLI2 by the proteasome 17/1332 60/10654 7.949585280026411e-4 0.0018762811036159895 8.179587105547072e-4 5684/5567/5568/7316/10213/5566/2736/2932/5688/5687/5685/5683/5708/5686/6233/7311/7314 17 Human_T.cell_leukemia_virus_1 R-HSA-8963898 Plasma lipoprotein assembly 8/1332 18/10654 8.016578131882708e-4 0.0018885496797581363 8.233071568521371e-4 5567/5568/348/338/335/336/5566/5034 8 Human_T.cell_leukemia_virus_1 R-HSA-182971 EGFR downregulation 11/1332 31/10654 8.698265112263242e-4 0.002045311684341525 8.916470483992424e-4 8027/7316/1950/867/6455/6233/2885/7311/1956/10254/7314 11 Human_T.cell_leukemia_virus_1 R-HSA-1852241 Organelle biogenesis and maintenance 56/1332 296/10654 8.848384810825204e-4 0.002076729121645169 9.053433791123197e-4 10694/80173/55763/79738/79867/8841/7531/10142/6608/54801/10575/23410/200186/10013/5465/4209/7203/10576/80321/9611/5469/10989/983/54205/5566/64784/1432/4208/1387/6950/55212/6604/3320/2101/11064/79600/6648/1069/117177/10498/5577/84808/1385/23054/26123/1386/5347/84790/22948/5600/1453/6300/23373/8648/814/10891 56 Human_T.cell_leukemia_virus_1 R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 20/1332 77/10654 9.683016409298862e-4 0.0022683863394595844 9.888957265989822e-4 5684/7316/10213/891/983/1026/5688/5687/5685/5683/5708/3320/5686/7157/6233/3326/7311/5347/84790/7314 20 Human_T.cell_leukemia_virus_1 R-HSA-2468052 Establishment of Sister Chromatid Cohesion 6/1332 11/10654 9.964880499290258e-4 0.002312881857584344 0.001008293404569863 10274/23244/10735/5885/8243/9126 6 Human_T.cell_leukemia_virus_1 R-HSA-376172 DSCAM interactions 6/1332 11/10654 9.964880499290258e-4 0.002312881857584344 0.001008293404569863 1432/5603/1630/5599/5600/6300 6 Human_T.cell_leukemia_virus_1 R-HSA-4755510 SUMOylation of immune response proteins 6/1332 11/10654 9.964880499290258e-4 0.002312881857584344 0.001008293404569863 51588/8517/5970/4792/7341/7329 6 Human_T.cell_leukemia_virus_1 R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 6/1332 11/10654 9.964880499290258e-4 0.002312881857584344 0.001008293404569863 6885/7316/7189/6233/7311/7314 6 Human_T.cell_leukemia_virus_1 R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 6/1332 11/10654 9.964880499290258e-4 0.002312881857584344 0.001008293404569863 6885/7316/7189/6233/7311/7314 6 Human_T.cell_leukemia_virus_1 R-HSA-354192 Integrin alphaIIb beta3 signaling 10/1332 27/10654 0.0010156312158365519 0.002343007401547086 0.0010214265385373878 6464/207/6850/6714/2244/2335/1445/6654/2885/7450 10 Human_T.cell_leukemia_virus_1 R-HSA-5654716 Downstream signaling of activated FGFR4 10/1332 27/10654 0.0010156312158365519 0.002343007401547086 0.0010214265385373878 5295/4893/6464/5290/5335/6654/2885/3845/3265/5781 10 Human_T.cell_leukemia_virus_1 R-HSA-9006921 Integrin signaling 10/1332 27/10654 0.0010156312158365519 0.002343007401547086 0.0010214265385373878 6464/207/6850/6714/2244/2335/1445/6654/2885/7450 10 Human_T.cell_leukemia_virus_1 R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 16/1332 56/10654 0.0010169173618797371 0.002343007401547086 0.0010214265385373878 5684/3315/26986/7316/10213/5688/5687/5685/5683/5708/5686/1981/6233/7311/3312/7314 16 Human_T.cell_leukemia_virus_1 R-HSA-166208 mTORC1-mediated signalling 9/1332 23/10654 0.0011485172069184732 0.0026317570970918747 0.0011473060393145903 6194/6198/29904/1981/6009/1977/1975/2475/1978 9 Human_T.cell_leukemia_virus_1 R-HSA-389948 PD-1 signaling 9/1332 23/10654 0.0011485172069184732 0.0026317570970918747 0.0011473060393145903 5777/919/29126/915/917/1445/916/3932/5781 9 Human_T.cell_leukemia_virus_1 R-HSA-73980 RNA Polymerase III Transcription Termination 9/1332 23/10654 0.0011485172069184732 0.0026317570970918747 0.0011473060393145903 5434/5440/4774/5441/5435/5437/4782/10621/4784 9 Human_T.cell_leukemia_virus_1 R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 11/1332 32/10654 0.0011775880162246681 0.002693464953473877 0.0011742073807713917 5295/5777/930/6850/4067/2534/695/6654/2885/7409/5293 11 Human_T.cell_leukemia_virus_1 R-HSA-4086398 Ca2+ pathway 17/1332 62/10654 0.0011908982901217729 0.0027189656061219424 0.0011853243082499642 815/6885/1499/4772/5578/5532/57690/27327/192670/5530/6934/192669/23112/4343/3845/26523/5592 17 Human_T.cell_leukemia_virus_1 R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 7/1332 15/10654 0.0012128636313391771 0.0027640986380881973 0.0012049999083289691 6737/7316/51428/3661/6233/7311/7314 7 Human_T.cell_leukemia_virus_1 R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 15/1332 52/10654 0.001299933099867746 0.0029412155389093968 0.0012822134514030587 5684/11200/7316/10213/993/5688/5687/5685/5683/5708/5686/1111/6233/7311/7314 15 Human_T.cell_leukemia_virus_1 R-HSA-69610 p53-Independent DNA Damage Response 15/1332 52/10654 0.001299933099867746 0.0029412155389093968 0.0012822134514030587 5684/11200/7316/10213/993/5688/5687/5685/5683/5708/5686/1111/6233/7311/7314 15 Human_T.cell_leukemia_virus_1 R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 15/1332 52/10654 0.001299933099867746 0.0029412155389093968 0.0012822134514030587 5684/11200/7316/10213/993/5688/5687/5685/5683/5708/5686/1111/6233/7311/7314 15 Human_T.cell_leukemia_virus_1 R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 15/1332 52/10654 0.001299933099867746 0.0029412155389093968 0.0012822134514030587 1019/5684/7316/10213/2932/5688/5687/5685/5683/5708/5686/595/6233/7311/7314 15 Human_T.cell_leukemia_virus_1 R-HSA-9020591 Interleukin-12 signaling 14/1332 47/10654 0.0013258441311032486 0.002994455865220622 0.0013054234003681234 9049/6775/3595/4478/6175/6950/3717/3458/6648/3716/3594/2939/3586/5034 14 Human_T.cell_leukemia_virus_1 R-HSA-8852135 Protein ubiquitination 20/1332 79/10654 0.0013651437507548427 0.003077689674640846 0.0013417089117964028 11065/7321/79577/7336/5591/7316/56254/8915/5111/7415/9810/7347/7324/5830/6233/7311/7334/7874/3105/7314 20 Human_T.cell_leukemia_virus_1 R-HSA-8948751 Regulation of PTEN stability and activity 18/1332 69/10654 0.0016161409506779522 0.003637039921203692 0.0015855558521856946 5684/207/7316/10213/1457/4734/5688/5687/5685/5683/5708/10000/5686/5728/208/6233/7311/7314 18 Human_T.cell_leukemia_virus_1 R-HSA-5260271 Diseases of Immune System 9/1332 24/10654 0.0016359852630922333 0.003668573014206826 0.001599302602628865 4790/7099/8517/5970/4792/695/81622/7187/3551 9 Human_T.cell_leukemia_virus_1 R-HSA-5602358 Diseases associated with the TLR signaling cascade 9/1332 24/10654 0.0016359852630922333 0.003668573014206826 0.001599302602628865 4790/7099/8517/5970/4792/695/81622/7187/3551 9 Human_T.cell_leukemia_virus_1 R-HSA-195721 Signaling by WNT 60/1332 331/10654 0.0017460380133414105 0.003908391140184154 0.0017038505430808668 9070/815/5684/7476/6662/7015/6885/1487/5579/6597/1499/4772/207/8085/5578/5532/57690/5929/5582/27327/79577/6657/192670/5530/55366/7316/10213/1457/6934/4609/2932/10524/5688/1387/5687/5685/5683/5708/5686/2033/192669/3065/23112/208/57680/6233/5527/1855/1488/1857/7514/7311/387/4343/3845/26523/9736/7314/4221/5592 60 Human_T.cell_leukemia_virus_1 R-HSA-5689880 Ub-specific processing proteases 43/1332 220/10654 0.0017538943560342457 0.003919003729824301 0.0017084770673905618 5684/7186/6885/7419/2625/63967/1080/3091/8517/7316/10213/993/890/4792/4092/8678/4609/4194/4089/5688/5687/6502/4088/5685/5683/5708/5686/408/5728/7157/8900/4087/63891/7189/6233/7311/367/1540/9736/7874/10254/7314/4193 43 Human_T.cell_leukemia_virus_1 R-HSA-2029481 FCGR activation 6/1332 12/10654 0.00178292617480629 0.003976810510472186 0.0017336777474320217 919/6850/6714/4067/917/2534 6 Human_T.cell_leukemia_virus_1 R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 16/1332 59/10654 0.0018635961936849387 0.004149387631248943 0.0018089121880015893 5684/23594/7316/10213/51053/5688/5687/5685/5683/5708/5686/990/81620/6233/7311/7314 16 Human_T.cell_leukemia_virus_1 R-HSA-156711 Polo-like kinase mediated events 7/1332 16/10654 0.0019251762326930471 0.004256365027641218 0.0018555486397799977 891/993/5928/2033/995/5347/7465 7 Human_T.cell_leukemia_virus_1 R-HSA-1834941 STING mediated induction of host immune responses 7/1332 16/10654 0.0019251762326930471 0.004256365027641218 0.0018555486397799977 6737/7520/6778/5591/51428/3661/2547 7 Human_T.cell_leukemia_virus_1 R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 7/1332 16/10654 0.0019251762326930471 0.004256365027641218 0.0018555486397799977 5590/7316/6233/7311/387/7040/7314 7 Human_T.cell_leukemia_virus_1 R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 7/1332 16/10654 0.0019251762326930471 0.004256365027641218 0.0018555486397799977 6885/7099/7316/7189/6233/7311/7314 7 Human_T.cell_leukemia_virus_1 R-HSA-5654727 Negative regulation of FGFR2 signaling 11/1332 34/10654 0.0020620262553895344 0.004542958019754875 0.001980487932635169 5594/7316/2263/6714/867/6233/2885/7311/5781/7314/5595 11 Human_T.cell_leukemia_virus_1 R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 11/1332 34/10654 0.0020620262553895344 0.004542958019754875 0.001980487932635169 7321/7706/7316/83737/3661/6233/7311/7187/5300/1540/7314 11 Human_T.cell_leukemia_virus_1 R-HSA-109704 PI3K Cascade 13/1332 44/10654 0.0021172509939706096 0.004656471591634662 0.0020299738090884937 5295/54106/5290/3667/5291/2263/2261/208/2885/8660/9846/5296/5781 13 Human_T.cell_leukemia_virus_1 R-HSA-73887 Death Receptor Signalling 30/1332 141/10654 0.002220752729404361 0.004875579290734181 0.002125493105574855 7124/8841/7186/4790/6885/10018/7531/356/8878/355/841/8517/7316/5970/4792/836/4803/3066/3065/7189/6654/6233/7409/7311/387/5599/1540/3551/8795/7314 30 Human_T.cell_leukemia_virus_1 R-HSA-5610780 Degradation of GLI1 by the proteasome 16/1332 60/10654 0.0022521917084784983 0.004927403772636436 0.00214808582172503 5684/5567/5568/7316/10213/5566/5688/5687/5685/5683/5708/5686/83737/6233/7311/7314 16 Human_T.cell_leukemia_virus_1 R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 16/1332 60/10654 0.0022521917084784983 0.004927403772636436 0.00214808582172503 5684/5567/5568/7316/10213/5566/2932/5688/5687/5685/5683/5708/5686/6233/7311/7314 16 Human_T.cell_leukemia_virus_1 R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 9/1332 25/10654 0.002276182610054962 0.004971246047654761 0.0021671987204653423 10694/10575/7203/10576/908/6950/10574/84790/22948 9 Influenza_A_virus R-HSA-3700989 Transcriptional Regulation by TP53 314/4622 365/10654 2.4402919623880755e-66 3.4115281634185296e-63 1.33830748674125e-63 6884/6875/834/5563/3725/9134/4436/83990/64769/9156/57060/1763/7531/1459/79370/7486/6874/10971/9997/133383/9212/5982/27327/7295/7533/2810/55367/1460/11200/472/53632/79813/5431/7001/639/5435/1869/5433/28996/84289/1457/6790/6341/25904/29117/4194/1647/5928/1432/1387/4683/56950/51499/2965/84126/5439/192669/1107/8900/6873/5371/8396/2475/672/55571/6881/51204/51616/5518/1386/55835/4343/6117/11198/7159/57472/144455/85456/29883/51497/51230/637/83695/7296/7314/5515/1263/27166/23368/9377/23774/6118/2176/3622/7027/6446/2936/7832/51422/7249/79837/898/117584/27244/7534/332/5438/5934/64065/116028/890/10769/983/1643/8797/9656/5519/27154/5458/57459/83860/2821/10000/5985/2877/900/7994/2068/54541/3066/7157/5984/1337/6233/1025/2353/604/63970/839/10419/5325/50484/5600/9167/6883/6829/79733/26523/7874/317/2744/5608/5884/5810/57521/26155/26013/5875/253260/25920/5170/80010/2963/5434/83667/1820/7862/1029/5457/9219/8445/7532/5436/55240/204851/6878/4869/5931/4850/4292/580/11073/891/80196/54971/4331/5366/641/5111/1108/8148/246175/64223/2962/84883/6119/147923/3364/5571/10524/54457/4848/8812/144715/23019/1616/843/6794/54815/94241/1874/10128/6009/905/1111/2071/55215/8626/208/79109/7311/7161/5562/6880/6908/5983/1340/4697/5564/6882/5565/1020/53615/10397/8795/5432/665/7248/6877/7529/5516/1017/27161/27113/9891/5440/27165/5305/8621/902/5883/25946/9540/5430/10111/8793/207/22974/57690/4849/1027/58484/3486/355/6749/545/5441/8794/192670/8550/9337/7316/6872/2539/1026/54205/5933/124446/5395/6879/9150/112858/5876/143686/10848/5437/9099/28984/51755/2033/995/5728/3065/91875/23112/10498/10542/5527/2968/5932/6834/8851/5300/7156/581/1327/3276/5052/138474/133746/1022/8178/10919/4193 314 Influenza_A_virus R-HSA-9006925 Intracellular signaling by second messengers 271/4622 305/10654 7.611848498057616e-64 5.320682100142274e-61 2.0872489828884308e-61 5295/1912/2308/5689/3725/6591/3643/5335/5682/23035/5291/1822/1459/5526/9112/817/6045/5578/5582/27327/80012/3082/1460/941/143471/2064/5705/5709/5695/107/1457/1911/4734/11060/5711/5928/5683/145957/2534/23512/9965/57332/5699/2444/2264/3630/5702/192669/1107/8975/3654/5371/9542/2885/8396/2475/51135/8660/5518/1386/2252/4343/80351/5696/814/5691/23252/7314/5879/5515/5718/818/23396/1839/5290/3667/8823/90865/2065/23186/5700/3815/122706/5707/5567/2146/51564/5594/2069/84335/84232/8074/7249/23198/79837/112/8395/2260/5573/5528/111/2249/6714/2099/9861/7101/81847/2248/5519/2932/84733/57459/2247/5698/5880/10000/5692/5713/5710/3066/7157/5613/5719/6233/5580/7409/2246/2251/5154/3932/2931/3710/118788/331/8726/196883/8394/115/26523/7874/801/5781/57521/23608/940/6015/253260/5170/3838/572/23239/9219/8535/4303/930/5931/5706/6199/113/2263/4233/8658/5714/10645/1108/2122/64223/5566/84254/10014/8503/5688/5159/5687/29851/5708/3084/54815/6009/5529/816/7189/208/5577/5704/10718/79109/57504/7311/5293/1956/648/2549/5694/23466/53615/109/5595/3556/5516/1147/27161/815/5684/8841/685/5305/5720/2309/5468/5525/5575/842/5978/10273/207/5690/57690/5717/1027/9491/8817/114/3708/10197/108/192670/4615/2100/2254/7316/10213/152831/1950/1026/50852/10768/26281/57167/10818/5715/1958/2261/5701/5576/5685/2255/3164/5686/391/5728/6615/3065/2066/27006/23028/942/5987/23112/10542/5527/5716/1385/5155/4254/5296/5581/5693/5721/5156/4193 271 Influenza_A_virus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 225/4622 244/10654 3.0982472999711993e-60 1.443783241786579e-57 5.663813485210509e-58 8449/23165/6633/8683/6431/84271/55696/4904/51639/51585/9128/199746/23450/348995/57122/5431/9092/23511/81608/5435/6625/5433/51645/3190/1477/9416/65109/56339/22826/23279/22938/988/23020/23225/6631/3181/5439/1660/9410/6638/57721/9877/9972/8021/3312/10907/10291/55746/26121/10262/7919/53981/6432/10084/8563/6430/51340/6627/6936/83443/11051/80145/9129/9879/8106/51690/27238/55749/5438/85313/10762/54883/22794/9785/11338/1655/9343/29107/3185/4116/6626/11157/285755/1478/24144/79902/9883/51213/10236/10250/4670/26097/51362/10465/55660/25949/23283/2521/1977/3191/10285/6636/23524/10914/57187/6396/129401/79228/8175/2733/84950/3188/84324/56259/5725/1994/10450/7536/4928/2963/6635/5434/5903/220988/6632/10283/55706/7175/24148/23350/5436/10523/6428/27258/10212/6637/55110/5093/84321/6429/57819/4927/10181/2962/10898/10569/23658/6434/9295/84844/10482/51692/10421/11193/8086/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/81929/5440/51691/10946/9631/27339/5430/79869/11325/57703/3184/25804/29894/9589/11017/51503/3178/79023/5441/23636/3183/10594/4686/8189/23398/10713/53371/10978/5546/7307/10772/9688/9984/5437/6629/10189/10949/51729/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/84248/6427/5356/84991/8480/10992/55339/6628 225 Influenza_A_virus R-HSA-5663205 Infectious disease 318/4622 383/10654 1.5319135283123046e-59 5.354037781451505e-57 2.1003340743439758e-57 3839/6158/6884/23165/6875/5689/6138/6227/7852/6206/6234/6191/162/6128/5682/6132/6129/27243/6874/6176/1174/811/6224/6146/348995/6154/143471/6202/57122/5705/6169/5431/23511/5435/5709/6175/9978/5433/6218/5695/292/567/51271/6173/23279/5605/6167/5711/23327/8732/23225/5683/2965/2534/6156/27183/5699/6143/5439/5702/6456/6873/3836/6139/30011/2885/163/9972/6881/51616/3921/8021/7040/1794/11198/51497/5062/55746/6208/5696/6170/5691/92421/7296/7314/5879/5718/137492/3303/8945/6203/1839/161/5606/6147/25978/5700/51160/122706/5707/2959/8027/6222/2060/8106/23198/84168/9636/91782/5438/6134/10762/79720/6155/1500/4836/926/9397/6714/6231/9861/79902/6142/9883/23521/83860/51510/999/5698/9146/6455/5692/5713/5710/2068/5902/6207/5478/5719/6233/6844/7514/1025/3932/1213/5610/1211/6188/6396/129401/6883/1175/6829/801/5608/8907/6122/940/25920/6230/60489/928/1173/4928/2963/3838/5434/5903/6857/6194/55706/7175/6166/1938/5436/6136/6878/6125/4869/821/5706/6232/160/6160/293/5611/920/4233/4331/5714/6193/4927/6210/6229/8148/6205/2962/10898/3840/5688/54457/8812/5687/5708/128866/140801/6235/905/6181/2071/5901/8086/5704/3326/7311/6223/25873/93343/6880/6908/7251/8905/5694/3304/1104/2547/9045/6882/2961/6187/6416/5432/6168/22916/1234/6157/6137/6877/5905/6144/3837/81929/5440/164/5684/9349/8065/4736/2926/5720/902/51121/9631/5604/1499/3159/6159/6217/3843/5430/6152/5690/7520/5717/9491/6500/127833/6749/51065/6141/79023/5441/23636/10197/919/6164/4686/7316/10213/6872/53371/3055/6209/9688/11224/6165/6130/6879/9150/5715/6204/5701/867/6228/5437/5685/3320/5686/6124/5609/2968/5716/9844/6189/6135/6201/375/6161/138474/1022/5693/10254/5721/6457/8178/8480/6133/291 318 Influenza_A_virus R-HSA-1257604 PIP3 activates AKT signaling 238/4622 264/10654 6.371075501506229e-59 1.7813527102211417e-56 6.988063865862621e-57 5295/1912/2308/5689/3725/6591/3643/5682/23035/5291/1822/1459/5526/9112/6045/27327/80012/3082/1460/941/143471/2064/5705/5709/5695/1457/1911/4734/11060/5711/5928/5683/145957/2534/23512/9965/57332/5699/2444/2264/3630/5702/192669/1107/8975/3654/5371/9542/2885/8396/2475/51135/8660/5518/1386/2252/4343/80351/5696/5691/23252/7314/5879/5515/5718/23396/1839/5290/3667/8823/90865/2065/23186/5700/3815/122706/5707/2146/51564/5594/2069/84335/84232/8074/7249/23198/79837/8395/2260/5528/2249/6714/2099/9861/7101/81847/2248/5519/2932/84733/57459/2247/5698/5880/10000/5692/5713/5710/3066/7157/5719/6233/7409/2246/2251/5154/3932/2931/118788/331/8726/8394/26523/7874/5781/57521/23608/940/6015/253260/5170/572/23239/9219/8535/4303/930/5931/5706/6199/2263/4233/8658/5714/1108/2122/64223/10014/8503/5688/5159/5687/29851/5708/3084/54815/6009/5529/7189/208/5704/10718/79109/57504/7311/5293/1956/648/2549/5694/23466/53615/5595/3556/5516/1147/27161/5684/8841/685/5305/5720/2309/5468/5525/842/5978/10273/207/5690/57690/5717/1027/9491/8817/10197/192670/4615/2100/2254/7316/10213/152831/1950/1026/50852/26281/57167/10818/5715/1958/2261/5701/5685/2255/3164/5686/391/5728/6615/3065/2066/27006/23028/942/5987/23112/10542/5527/5716/1385/5155/4254/5296/5693/5721/5156/4193 238 Influenza_A_virus R-HSA-72163 mRNA Splicing - Major Pathway 177/4622 183/10654 1.637778613328847e-56 3.816024169056213e-54 1.4969871184988235e-54 8449/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/5431/9092/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/22938/988/23020/6631/3181/5439/1660/9410/6638/3312/10907/10291/26121/10262/53981/6432/10084/6430/51340/6627/6936/83443/11051/9129/9879/8106/51690/27238/55749/5438/85313/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/10236/10250/4670/51362/10465/55660/25949/23283/2521/3191/10285/6636/23524/10914/8175/84950/3188/56259/5725/1994/10450/7536/2963/6635/5434/220988/6632/10283/24148/23350/5436/10523/6428/27258/6637/55110/5093/6429/57819/10181/2962/10898/10569/23658/6434/9295/84844/51692/10421/11193/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/51691/10946/27339/5430/79869/11325/57703/3184/25804/29894/11017/51503/3178/5441/3183/10594/4686/8189/23398/10713/10978/5546/7307/10772/5437/6629/10189/10949/51729/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/84991/10992/55339/6628 177 Influenza_A_virus R-HSA-5663202 Diseases of signal transduction 306/4622 377/10654 5.59555112938001e-53 1.1175114969818934e-50 4.3838829148977226e-51 5295/8454/2308/27123/5689/4893/11052/5335/71/79718/5682/5291/892/5526/817/1452/9530/613/9372/5908/3082/941/143471/23385/2064/5705/5431/6776/5435/5709/9978/5433/5695/8546/9759/9612/5605/4609/145226/4089/22938/5037/5711/1387/3717/4088/6907/5683/145957/324/2534/3690/408/9965/5699/6400/8312/11064/5439/2264/5702/4296/5894/9794/9542/2885/2475/8660/8826/9846/5518/2252/6469/4140/7040/3845/3265/80351/4763/5696/7750/5691/7314/5879/5515/5718/818/8805/1839/26127/5290/3667/8823/79885/2065/2648/9734/55869/55750/5700/3815/122706/5707/8844/51564/7094/8322/5594/3280/2069/84335/8074/7249/23198/7414/10533/10013/23164/2260/5438/5528/3714/89780/102/57085/2249/6714/2099/5664/9861/2248/5519/9061/8850/399687/2932/7046/2247/5698/5880/10000/5692/5713/2335/1445/5710/3066/2280/5719/6233/7409/2246/4040/2251/5154/3932/2931/7855/118788/6777/369/801/5781/5663/940/1523/57670/253260/5170/2963/5434/7276/6464/572/283455/3674/5436/4303/4041/409/930/5706/6199/9208/84447/673/8315/6774/2263/4233/8658/1024/5714/6772/6934/64223/10014/2962/8503/5688/5159/5687/29851/5708/3084/5529/816/4087/208/6654/5704/10718/79109/56829/7048/7311/5293/1956/11160/60/2549/5694/4851/5432/22916/11140/7529/5595/5516/4000/1147/27044/815/5440/5684/22906/8841/685/5720/1487/2309/5604/1499/10018/5525/10142/842/139285/5430/23462/207/5690/5717/1027/9491/6500/8817/5441/10197/2100/2254/4686/7316/10213/152831/1950/9611/1026/50852/26281/10818/7415/5715/2261/5701/867/5437/5685/2255/3164/3320/5686/2033/54894/391/55294/5728/3065/2066/27006/942/5527/1488/5716/1385/5906/5155/4254/5296/3516/9715/5693/5721/5245/5156/4193 306 Influenza_A_virus R-HSA-68877 Mitotic Prometaphase 187/4622 200/10654 1.2288709815567748e-52 2.147452040270464e-50 8.424233965672101e-51 114791/10844/55839/11130/440145/6249/9735/7531/1459/11190/203068/5526/54801/51807/9212/347688/10274/1460/147841/348995/79441/10381/57122/5116/1780/23122/5048/57405/8655/1457/23279/9702/2491/7846/7840/1060/11064/11004/9184/5518/55835/29922/23332/25909/10726/81930/55746/93323/5515/79682/10403/79861/25936/55869/1454/3619/64105/332/10051/5528/983/79902/3796/79959/5519/81565/80097/91687/11243/10376/23397/10540/85378/83540/7514/54930/54820/113130/6396/1453/27229/64946/9793/140735/220134/84617/4928/5903/11258/22981/55055/8636/80776/1783/401541/7532/55125/10382/79172/121441/7277/9133/79980/6232/23047/9814/653784/5885/23354/891/5501/9738/1639/55722/4957/5566/54821/9183/1062/699/7283/347733/22919/8243/10426/5529/22994/51143/1069/5577/10383/5347/84790/84643/80184/22897/5108/10592/7280/10806/1778/5516/115106/4926/5905/22995/55559/81929/54908/55143/5525/10142/1058/991/79019/348235/80152/1063/8379/95681/23244/23421/55920/79023/10735/1781/80321/4085/100527963/55166/10121/84131/3320/79003/9126/9918/10733/4751/5527/27175/80254/701/57551/9662/55142/8481/55755 187 Influenza_A_virus R-HSA-2467813 Separation of Sister Chromatids 179/4622 190/10654 8.609144430060505e-52 1.3372871014693985e-49 5.246040056212308e-50 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/5698/5692/5713/91687/119504/11243/10376/5710/7324/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/347733/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7280/1778/5516/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/1781/7316/10213/4085/100527963/55166/5715/5701/5685/5686/79003/9126/9232/9700/5527/5716/701/57551/5693/5721 179 Influenza_A_virus R-HSA-68882 Mitotic Anaphase 187/4622 201/10654 1.020018198144549e-51 1.4259854410060798e-49 5.593994539298e-50 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/5520/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/7444/5698/5692/5713/91687/119504/11243/10376/5710/7324/83540/2010/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/347733/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/7443/23141/1781/7316/10213/4085/100527963/55166/5715/5701/5685/5686/79003/9126/9232/23592/9700/5527/5716/701/57551/5693/5721 187 Influenza_A_virus R-HSA-5633007 Regulation of TP53 Activity 156/4622 160/10654 1.7104262935275456e-51 2.173796325774099e-49 8.527579894046423e-50 6884/6875/5563/83990/64769/9156/1763/1459/7486/6874/133383/9212/5982/1460/11200/472/53632/79813/639/28996/84289/1457/6790/29117/4194/5928/1432/4683/56950/84126/1107/8900/6873/5371/8396/2475/672/6881/51616/5518/6117/11198/7159/51230/83695/7314/5515/1263/23368/23774/6118/3622/6446/51422/79837/117584/116028/890/983/5519/27154/5458/57459/83860/10000/5985/900/7994/3066/7157/5984/6233/10419/5600/6883/7874/5608/5884/5810/26155/26013/253260/5170/80010/7862/1029/5457/9219/8445/204851/6878/5931/580/11073/80196/54971/641/1108/8148/64223/6119/3364/5571/10524/54457/144715/1616/6794/54815/94241/1111/8626/208/79109/7311/7161/5562/6880/6908/5983/5564/6882/5565/1020/53615/6877/5516/1017/9891/5305/5883/25946/10111/207/22974/6749/545/8550/7316/6872/6879/112858/10848/9099/2033/3065/91875/5527/5932/8851/5300/7156/138474/133746/10919/4193 156 Influenza_A_virus R-HSA-2555396 Mitotic Metaphase and Anaphase 187/4622 202/10654 7.941067510344229e-51 9.251343649551028e-49 3.6292071692011785e-49 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/5520/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/7444/5698/5692/5713/91687/119504/11243/10376/5710/7324/83540/2010/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/347733/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/7443/23141/1781/7316/10213/4085/100527963/55166/5715/5701/5685/5686/79003/9126/9232/23592/9700/5527/5716/701/57551/5693/5721 187 Influenza_A_virus R-HSA-453274 Mitotic G2-G2/M phases 184/4622 198/10654 1.0744376317645257e-50 1.1554336993898515e-48 4.5326478230714e-49 114791/10844/8454/5689/440145/5682/7531/11190/203068/54801/51807/63943/347688/51400/79441/143471/10381/5705/5116/5048/5709/9978/1869/5695/8655/6790/9702/5711/5928/7846/7840/5683/5699/11064/5702/5520/8900/5518/55835/29922/23332/7465/93323/5696/5691/7314/5515/5718/8945/79861/4659/5700/122706/5707/1454/23198/993/890/983/9861/79959/5519/5698/5692/5713/80097/10376/5710/10540/7157/85378/5719/6233/7514/54930/54820/1453/27229/9793/4218/5500/84617/2305/11258/22981/8636/51512/7532/84962/55125/10382/121441/7277/5706/9133/286826/9814/653784/23354/728642/891/9738/4331/1639/5714/55722/4957/5566/5688/5687/7283/347733/5708/22919/984/10426/22994/79866/1069/5577/5704/3326/55957/7311/10133/10383/5347/84790/80184/5694/22897/5108/7280/10806/1778/5516/115106/1017/22822/22995/55559/5684/994/5720/902/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/1781/7316/10213/80321/1026/10121/1871/5715/84131/9088/5701/23291/5685/3320/5686/2033/995/10733/4751/27175/80254/5716/9662/55142/1022/8481/5693/5721/55755 184 Influenza_A_virus R-HSA-69275 G2/M Transition 182/4622 196/10654 5.149863925166701e-50 5.1425069767021774e-48 2.0173527105352268e-48 114791/10844/8454/5689/440145/5682/7531/11190/203068/54801/51807/63943/347688/51400/79441/143471/10381/5705/5116/5048/5709/9978/5695/8655/6790/9702/5711/5928/7846/7840/5683/5699/11064/5702/5520/8900/5518/55835/29922/23332/7465/93323/5696/5691/7314/5515/5718/8945/79861/4659/5700/122706/5707/1454/23198/993/890/983/9861/79959/5519/5698/5692/5713/80097/10376/5710/10540/7157/85378/5719/6233/7514/54930/54820/1453/27229/9793/4218/5500/84617/2305/11258/22981/8636/51512/7532/84962/55125/10382/121441/7277/5706/9133/286826/9814/653784/23354/728642/891/9738/4331/1639/5714/55722/4957/5566/5688/5687/7283/347733/5708/22919/984/10426/22994/79866/1069/5577/5704/3326/55957/7311/10133/10383/5347/84790/80184/5694/22897/5108/7280/10806/1778/5516/115106/1017/22822/22995/55559/5684/994/5720/902/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/1781/7316/10213/80321/1026/10121/5715/84131/9088/5701/23291/5685/3320/5686/2033/995/10733/4751/27175/80254/5716/9662/55142/1022/8481/5693/5721/55755 182 Influenza_A_virus R-HSA-72172 mRNA Splicing 177/4622 191/10654 2.5667145035177066e-48 2.3921779172785028e-46 9.384268465492808e-47 8449/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/5431/9092/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/22938/988/23020/6631/3181/5439/1660/9410/6638/3312/10907/10291/26121/10262/53981/6432/10084/6430/51340/6627/6936/83443/11051/9129/9879/8106/51690/27238/55749/5438/85313/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/10236/10250/4670/51362/10465/55660/25949/23283/2521/3191/10285/6636/23524/10914/8175/84950/3188/56259/5725/1994/10450/7536/2963/6635/5434/220988/6632/10283/24148/23350/5436/10523/6428/27258/6637/55110/5093/6429/57819/10181/2962/10898/10569/23658/6434/9295/84844/51692/10421/11193/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/51691/10946/27339/5430/79869/11325/57703/3184/25804/29894/11017/51503/3178/5441/3183/10594/4686/8189/23398/10713/10978/5546/7307/10772/5437/6629/10189/10949/51729/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/84991/10992/55339/6628 177 Influenza_A_virus R-HSA-913531 Interferon Signaling 182/4622 199/10654 1.8907109308971385e-47 1.6520086758713747e-45 6.4806604934040075e-46 80263/3839/3443/23165/201626/5777/3442/5335/960/5770/3107/817/9021/348995/317649/3383/57122/11274/3662/3115/23511/4684/567/4734/6672/3113/23279/3106/8672/3459/3717/23225/3117/1973/11074/3836/5371/4599/684/9972/3133/3429/8021/3127/91543/7334/4938/4261/55746/5696/7314/3445/818/115362/7412/10410/85363/9830/163351/9636/3126/2634/3444/10762/2317/115361/103/3434/3433/79902/23586/9883/3447/3451/10437/3448/1981/3458/3661/7324/1977/3439/51191/6233/5580/81603/10107/5610/10581/3452/4940/6396/3437/129401/6773/7297/5781/3430/3660/3446/8554/3135/3665/3120/4928/3838/5903/10379/55706/7175/3455/2316/2633/4600/3123/23650/2209/8638/25820/1982/7706/9470/3122/3394/3663/6772/8651/4927/3659/3840/25939/2635/3440/3454/816/8086/9246/3716/7311/7318/3125/7726/3456/3105/1974/5595/3460/815/3837/81929/3441/6737/51447/9631/23321/4281/3119/4502/54739/79023/2537/23636/3449/51127/7316/53371/8519/3664/9688/6041/1958/4939/388646/7341/6059/3669/3134/5300/9775/5495/5724/8480 182 Influenza_A_virus R-HSA-69620 Cell Cycle Checkpoints 241/4622 293/10654 9.948961255210784e-44 8.181557549873339e-42 3.209541061278525e-42 5689/55839/11130/9134/83990/11065/6249/5682/9156/57060/9735/1763/7531/7486/7321/5526/10971/8697/9212/5982/7533/2810/147841/348995/11200/143471/472/57122/5705/1780/23122/5048/5709/4174/5695/57405/8655/84515/23279/4194/5711/2491/4683/10926/5683/1060/165918/84126/5699/5702/8900/51529/29945/8924/11004/51434/55388/672/9184/5518/6117/29882/7334/5001/23332/7465/25909/51230/10726/81930/55746/5696/83695/5691/7314/996/5515/5718/6118/79682/10403/25936/5700/122706/5707/51588/51720/3619/23198/63967/898/64105/7534/332/5528/993/116028/890/983/51433/9861/79902/3796/9656/5519/81565/5698/5692/5985/5713/91687/119504/11243/5710/7157/5984/7324/83540/5719/64682/6233/7514/7158/54820/6396/64946/9793/5884/5810/140735/220134/4172/80010/4928/5903/8318/246184/55055/51512/1029/80776/1783/401541/7532/79172/4173/5706/9133/79980/6232/580/8881/11073/891/5501/641/5714/54821/6119/9183/3364/10524/5688/1062/699/5687/144715/5708/22919/5529/51143/1111/10393/5704/7311/25906/5347/84643/5983/5694/4176/7529/1778/5516/1017/5905/81929/5684/5720/54908/55143/5883/5525/25946/1058/991/79019/10111/8317/348235/80152/5690/1063/8379/5717/1027/9491/23421/545/55920/79023/10197/7336/29086/1781/7316/10213/4085/1026/100527963/4171/55166/5715/9088/7341/5701/5685/5686/995/79003/5527/5716/701/5932/9025/79184/57551/7156/5693/5721/4193 241 Influenza_A_virus R-HSA-373076 Class A/1 (Rhodopsin-like receptors) 267/4622 335/10654 2.11067209676553e-43 1.6392886618212284e-41 6.43076118371252e-42 729230/2532/10316/2149/23620/1880/7852/10161/338442/64805/1237/3354/2841/4987/51289/2150/3060/3576/6360/2798/5737/338557/4985/2920/3061/2921/1236/6010/554/2840/2831/5367/5028/4988/6370/58191/6755/6866/1524/94233/643/5029/2867/185/339403/8843/64106/2847/2833/6347/9290/9170/187/6750/2587/53829/8111/6387/4544/4543/2922/10663/4889/9283/727/1909/117579/3579/6375/23566/2358/1131/6846/5179/27334/5021/6865/6367/2797/8811/56923/2832/2693/27199/2826/6376/165140/27198/7201/5443/6354/3627/3361/6346/553/257313/134/9034/3814/10800/2863/1129/51554/51083/2829/1233/6366/1241/2861/728/183/10022/6373/57121/4922/5731/2865/1132/1814/6357/552/2925/8698/9934/2151/6869/6361/23596/2147/1813/50865/10886/2837/10803/146/3357/351/11251/8477/84432/3352/8484/2828/3062/1907/148/6351/6863/6752/1903/84539/6753/3577/594857/5368/6754/6915/8862/10911/301/5032/56670/150/2853/29933/6751/5020/4935/887/4829/186/53637/60675/10563/5540/2864/1901/5733/256933/7200/5729/10850/624/2796/4852/4828/680/5473/4283/1910/6870/128674/11255/885/10874/84634/147/6356/56477/387129/3350/129521/1234/151/57007/1238/3356/84109/9294/4923/1128/283869/4986/6374/5539/2852/1230/3358/4886/2919/1908/5196/3827/5173/2357/6352/57105/1133/140/3269/6348/886/2862/152/1906/6364/7253/5031/8620/5030/5697/56413/3355/3351/6288/6372/719/6363/1268/2359/347148/2846/5660/1815/1325/1232/4295/1902/551/154/9002/1269/59340/5724/4887/718/623 267 Influenza_A_virus R-HSA-168254 Influenza Infection 145/4622 155/10654 4.700526872321029e-41 3.4585981934235785e-39 1.3567725764428014e-39 3839/6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/23225/6156/6143/5439/3836/6139/9972/3921/8021/7040/55746/6208/6170/3303/6203/6147/6222/8106/9636/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/7514/1213/5610/1211/6188/6396/129401/6122/6230/4928/2963/3838/5434/5903/6194/55706/7175/6166/5436/6136/6125/821/6232/6160/293/5611/6193/4927/6210/6229/6205/2962/10898/3840/140801/6235/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/81929/5440/9349/4736/2926/51121/9631/6159/6217/3843/5430/6152/51065/6141/79023/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 145 Influenza_A_virus R-HSA-68886 M Phase 300/4622 395/10654 5.31675659191621e-41 3.716412857749431e-39 1.4579106233622872e-39 114791/10844/23165/5689/55839/11130/11065/440145/6249/5579/5682/9735/7531/1459/11190/7321/91754/203068/5526/54801/51807/8697/5578/9212/347688/10274/5861/5925/1460/147841/348995/79441/143471/10381/57122/5705/5116/1780/23122/23511/5048/5709/5695/57405/8655/1457/23279/9702/5711/2491/10112/7846/23225/7840/5683/1060/5699/11064/5702/5520/51529/29945/11004/23133/51434/9184/9972/5518/55835/29922/8021/29882/23332/25909/10726/81930/55746/93323/5696/5691/7314/996/5515/5718/79682/10403/79861/25936/55869/5700/122706/5707/1454/2801/5594/3619/23198/64105/332/10762/10051/5528/983/8548/51433/9861/79902/3796/8615/79959/5519/9883/81565/7444/5698/5692/5713/80097/91687/119504/11243/10376/23397/5710/10540/85378/7324/83540/2010/64900/5719/64682/6233/23175/7514/54930/54820/113130/6396/129401/1453/27229/64946/9793/140735/220134/84617/4928/5903/55706/7175/11258/22981/246184/55055/8636/80776/1783/401541/7532/55125/10382/79172/121441/7277/5706/9133/79980/25836/6232/23047/8881/9814/653784/5885/23354/891/5501/9738/1639/5714/55722/4957/4927/5566/54821/9183/5688/1062/699/5687/7283/347733/5708/22919/8243/10426/5529/22994/51143/1069/8086/10393/5577/5704/7311/25906/10383/5347/84790/84643/80184/5694/22897/6418/5108/7112/10592/7280/10806/5595/1778/5516/4000/115106/4926/5905/22995/55559/81929/5684/5720/54908/55143/9631/5525/10142/1058/991/79019/5862/348235/80152/5690/1063/8379/95681/5717/9491/140609/23244/23421/55920/79023/23636/10735/10197/7443/23141/1781/7316/10213/80321/10776/53371/26003/4085/100527963/9688/55166/10121/5715/84131/5701/5685/3320/5686/79003/9126/9918/10733/23399/4751/9232/23592/9700/5527/27175/80254/5716/701/57551/9662/55142/64689/8481/5693/5721/55755/8480 300 Influenza_A_virus R-HSA-168255 Influenza Life Cycle 136/4622 144/10654 6.947084382289133e-40 4.6247733173524795e-38 1.8142511093597183e-38 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/23225/6156/6143/5439/3836/6139/9972/3921/8021/55746/6208/6170/3303/6203/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/7514/1213/1211/6188/6396/129401/6122/6230/4928/2963/5434/5903/6194/55706/7175/6166/5436/6136/6125/821/6232/6160/5611/6193/4927/6210/6229/6205/2962/140801/6235/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/81929/5440/9349/4736/2926/51121/9631/6159/6217/3843/5430/6152/51065/6141/79023/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 136 Influenza_A_virus R-HSA-449147 Signaling by Interleukins 336/4622 461/10654 2.6228489904840136e-39 1.6667013130439323e-37 6.538298201158714e-38 5295/729230/8454/3605/7124/2308/834/1052/5689/3725/7291/5777/9252/1437/4790/5682/5291/26469/759/356/3593/5803/9021/8878/6624/5908/3082/5743/3091/941/143471/3383/5705/11009/6097/6657/3576/3313/3662/6776/3688/4985/5709/6175/9978/2920/5695/84868/1435/4792/7133/3606/4609/5898/5711/4988/1432/3558/3717/4088/836/5683/200081/2534/5699/3181/5702/3654/3563/2885/51135/8660/282618/6196/3594/9846/6347/5518/282617/1386/6382/9235/7040/6197/4282/7334/3600/3312/1399/3551/282616/3569/5062/5696/5691/51231/4692/7314/3572/3596/5515/257397/3598/5718/8945/1326/5601/1072/3635/3592/5290/3667/6627/5606/90865/9049/11213/7412/5700/122706/5707/27250/8767/3911/1849/29110/1439/5594/4582/23198/23118/6367/4312/8517/6778/7534/332/5528/4313/3565/3185/5970/5443/9261/3718/3627/9861/149233/5519/5598/3567/598/2247/5698/5692/5713/2335/595/6195/5710/3458/10454/7157/5478/5719/6233/7525/6844/7409/2353/604/6809/3932/7076/302/51561/8835/5600/6777/6773/7850/7297/5781/5608/4791/1846/3557/9655/3562/351/6464/3566/6597/5782/387522/6351/7184/9180/3589/54472/821/4318/5706/58480/301/4478/1438/79155/6774/920/6850/1440/5714/6772/8651/7867/5566/64127/8503/1901/3552/2889/5688/79923/5687/4067/29760/3636/5708/5602/29949/3656/57162/998/6648/7189/163702/6654/5704/3716/7311/6888/5293/2185/6356/5694/6416/1234/3586/3554/829/5595/3556/5516/1147/596/5684/5720/6885/2309/5604/4215/3561/3578/10392/207/5292/5451/7422/5690/3553/2625/1230/5717/2919/9491/6500/3568/25930/246330/10197/4615/2357/1436/7316/10213/3560/6352/4314/7335/4205/3055/1026/6348/4793/5775/3146/6647/6364/5715/7132/5701/867/6950/23291/5685/3320/5686/4843/6288/942/6285/5609/1398/5716/1385/53832/6363/3575/4507/6845/5896/5296/5599/7431/375/3977/3559/3574/3162/57161/4170/5693/5721/5724/5034 336 Influenza_A_virus R-HSA-500792 GPCR ligand binding 340/4622 468/10654 2.801637941471866e-39 1.702908627033769e-37 6.680335778063351e-38 2788/729230/2532/10316/2149/23620/1880/7852/10161/50833/5726/338442/2740/64805/1237/11211/2550/50832/3354/2841/4987/51289/259294/2150/3060/2912/3576/6360/2798/5737/338557/4985/2920/3061/2921/1236/259295/6010/9568/554/2911/2840/2831/5367/5028/4988/6370/58191/6755/6866/1524/94233/643/5029/2782/2867/185/339403/2914/8843/64106/2847/2833/6347/9290/9170/6469/187/6750/259296/259289/50835/2587/53829/8111/2787/6387/4544/4543/2922/10663/4889/9283/727/1909/338398/117579/3579/6375/23566/2358/2916/259293/1131/8322/6846/5179/27334/10681/5021/6865/6367/2797/8811/56923/2832/2693/27199/2826/5727/6376/165140/27198/7201/89780/5443/7477/6354/3627/2792/54429/3361/6346/553/257313/134/9034/3814/10800/2863/1129/51554/51083/2785/2783/2784/2829/1233/222545/6366/1241/2861/728/7474/183/10022/6373/57121/4922/5731/2865/7855/1132/1814/80835/6357/552/2925/8698/9934/2151/6869/6361/50840/2791/23596/2147/1813/7976/50865/10886/2837/10803/8643/146/2913/3357/351/11251/8477/84432/3352/8484/2828/3062/1907/148/6351/6863/6752/1903/84539/6753/3577/594857/2918/5368/6754/6915/8862/10911/301/5032/2642/56670/150/2853/29933/6751/5020/4935/887/4829/186/53637/60675/10563/5540/2864/1901/5733/256933/7200/5729/10850/624/2641/2796/4852/4828/2786/680/50838/5473/4283/1910/6870/128674/11255/885/10874/83756/84634/147/6356/56477/387129/259286/3350/129521/1234/151/57007/1238/3356/84109/9294/54331/4923/1128/283869/59345/4986/6608/6374/5539/259287/2852/50836/1230/846/3358/4886/2919/7433/1908/51764/94235/259290/5196/3827/1604/5173/2357/55970/2778/6352/57105/1133/140/54361/3269/6348/886/2862/152/1906/6364/7253/80834/259292/5031/8620/2793/5030/5697/56413/3355/3351/6288/6372/50834/259285/719/6363/2917/1268/50831/2359/50839/347148/2846/5660/1815/1325/1232/4295/1902/551/154/50837/9002/1269/2915/59340/5724/4887/2790/718/623 340 Influenza_A_virus R-HSA-375276 Peptide ligand-binding receptors 175/4622 201/10654 1.1295238753063912e-38 6.579476573659729e-37 2.5810611361167975e-37 729230/2532/10316/2149/23620/7852/1237/4987/51289/2150/3060/3576/6360/4985/2920/3061/2921/1236/554/2831/5367/4988/6370/58191/6755/6866/1524/643/185/339403/64106/2847/2833/6347/187/6750/2587/6387/2922/10663/4889/9283/727/1909/117579/3579/6375/2358/6846/5179/5021/6865/6367/8811/56923/2832/2693/2826/6376/7201/5443/6354/3627/6346/553/257313/9034/3814/51554/51083/2829/1233/6366/2861/728/183/10022/6373/4922/6357/552/2925/2151/6869/6361/2147/50865/10886/2837/10803/351/84432/8484/3062/1907/6351/6863/6752/84539/6753/3577/594857/5368/6754/8862/10911/301/6751/5020/887/4829/186/60675/10563/5540/256933/7200/10850/624/4852/4828/680/5473/4283/1910/6870/128674/885/10874/84634/6356/56477/387129/129521/1234/57007/1238/84109/4923/283869/4986/6374/5539/2852/1230/4886/2919/1908/5196/3827/5173/2357/6352/6348/886/2862/1906/6364/8620/5697/6288/6372/719/6363/2359/347148/5660/1325/1232/4295/551/9002/4887/718/623 175 Influenza_A_virus R-HSA-5683057 MAPK family signaling cascades 235/4622 294/10654 1.1958529509814476e-38 6.687209701888255e-37 2.623323736679302e-37 2308/5689/2118/3725/2674/4893/6711/1437/71/5682/1844/5526/817/27327/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/2668/5605/4609/5037/5711/3558/3717/5683/145957/2534/3690/408/9965/5699/2264/5702/192669/4296/5894/3563/1741/9542/1739/2885/6709/8660/8826/5518/2252/1740/4140/4343/3845/5623/3265/4763/3569/5062/5696/5691/7314/3572/5879/5515/5718/818/1839/3667/8823/2065/5700/3815/122706/5707/5567/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/3337/4902/2260/5528/983/3718/2249/25780/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/80824/1445/5710/8555/896/5719/6233/2246/7514/2251/5154/1843/26523/369/801/7297/5781/8682/1846/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/3315/409/5706/1438/673/2676/8315/2263/4233/5597/84078/5714/5566/5688/5159/5687/5708/3084/5063/5529/816/998/9693/6654/5704/10718/3716/7311/1956/60/5536/5694/5058/7529/5595/5516/27161/815/5684/685/5720/2309/5604/3561/5525/153090/10642/10048/5690/57690/5717/9491/3568/8817/10817/10197/192670/5596/8550/2254/7316/10213/152831/1950/3560/26281/10818/5715/2261/5701/27040/5685/2255/5686/2066/6708/27006/8556/5979/23112/1742/5527/5716/88/5906/5155/9048/4254/5896/3559/8202/5693/5721/5245/5156/161742/284 235 Influenza_A_virus R-HSA-8856828 Clathrin-mediated endocytosis 136/4622 146/10654 5.429397655416296e-38 2.919345354719993e-36 1.145229222053397e-36 5869/85439/71/8674/5286/4738/1212/23208/1785/29763/950/8871/10094/554/54874/55738/10980/22848/7037/2017/3482/408/9322/10987/6456/185/8976/30011/2885/163/11037/1759/23149/3312/29993/9185/7314/9856/23396/1839/161/7018/25977/5868/10618/10093/8027/1856/9892/8322/2060/2069/1601/6453/55707/8301/1129/9146/6455/4074/26119/29979/6233/90019/7474/6844/1213/2580/1211/29924/4036/1175/85021/10109/6869/1173/6857/84251/23048/9026/29988/409/112574/382/160/338/8218/920/22905/26052/8867/10092/9829/2873/10097/7311/1956/60/8533/274/51429/8673/3092/50618/51138/9318/685/127833/1080/29978/58513/7316/1950/273/10552/26130/3267/3949/867/9341/915/917/6572/115548/5878/10096/143425/3575/6845/551/154/10254/6457/50813/4952/11252 136 Influenza_A_virus R-HSA-168273 Influenza Viral RNA Transcription and Replication 126/4622 134/10654 1.910610865211225e-36 9.892718479871455e-35 3.8808119328461925e-35 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/23225/6156/6143/5439/6139/9972/3921/8021/55746/6208/6170/6203/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/23521/6207/6233/6188/6396/129401/6122/6230/4928/2963/5434/5903/6194/55706/7175/6166/5436/6136/6125/6232/6160/5611/6193/4927/6210/6229/6205/2962/140801/6235/6181/8086/7311/6223/25873/9045/6187/5432/6168/6157/6137/6144/81929/5440/9349/4736/2926/51121/9631/6159/6217/3843/5430/6152/51065/6141/79023/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 126 Influenza_A_virus R-HSA-416476 G alpha (q) signalling events 183/4622 217/10654 2.5848443926137198e-36 1.2905758788835644e-34 5.062796723878752e-35 5295/2788/10316/2149/23620/4893/10161/5331/5578/2150/3060/5583/2769/2798/5737/338557/3061/2911/2840/5367/5028/6866/94233/5029/2782/2867/2776/185/2885/6196/64106/2847/9170/6197/3845/3265/5998/8111/2787/2922/1839/5290/1909/6375/23566/2358/1131/6846/5594/27334/10681/5021/6865/2797/56923/2693/7201/2792/553/257313/5598/3814/10800/5588/2863/2785/6195/2783/2784/2829/222545/8525/1241/5332/183/5580/57121/4922/5731/8527/2865/3710/552/2925/2151/6869/2791/2147/10886/2520/2837/146/3357/351/8477/84432/2828/3062/1907/148/7204/6863/84539/594857/6915/221955/10911/301/5032/2642/29933/5020/4935/887/4829/60675/8503/2864/23236/7200/624/2641/2796/4828/695/2786/680/6654/1910/6870/128674/885/1956/10874/84634/147/387129/129521/5595/3356/84109/54331/4923/1128/59345/26090/846/3358/1908/51764/94235/3708/5330/3827/55970/57105/1133/4314/3269/2767/886/2862/1906/5031/8620/2793/56413/6288/2869/1385/5296/5581/347148/2846/9630/4295/1902/551/9002/2915/5724/2790/623 183 Influenza_A_virus R-HSA-418594 G alpha (i) signalling events 298/4622 406/10654 7.64559465788366e-36 3.6857039074901224e-34 1.4458638173348047e-34 2788/729230/10316/6000/1880/7852/50833/29899/5331/5726/338442/64805/2770/817/1237/2550/5578/50832/3354/2841/5582/4987/51289/259294/2912/3576/6360/5530/4985/2920/2921/1236/259295/107/6010/9568/2840/2831/145226/5367/4988/6370/58191/2774/6755/1524/643/2782/5499/339403/2914/8843/2847/2833/10636/9290/5518/9170/6382/187/6750/259296/259289/5998/50835/2587/53829/814/2773/5515/2787/6387/818/4544/4543/126006/10663/4889/9283/727/338398/117579/3579/84152/23566/2358/5567/2916/259293/5594/5179/10681/5142/112/8811/5573/348/56923/2832/5528/27199/2826/8786/6376/165140/27198/111/5443/4836/3627/2792/9397/54429/6714/3361/6346/10988/5519/134/5588/1129/6011/51083/2785/2783/2784/1233/6366/5613/2861/2771/728/5332/183/10022/5580/23173/6373/57121/3710/1132/1814/80835/4036/6357/196883/9672/115/8698/801/9934/50840/2791/23596/50865/10803/2913/3838/7276/351/11251/3352/8484/6351/6752/1903/84539/6753/3577/2918/5368/6754/131890/8862/301/56670/150/113/338/2868/2853/6751/186/53637/10645/5566/84254/10563/5540/1901/5733/23236/256933/10850/624/4852/816/2786/50838/5577/5473/4283/11255/10874/83756/51109/56477/1020/5141/259286/3350/129521/1234/109/9628/5516/151/57007/815/26086/5321/9294/54331/283869/2817/5575/59345/63940/4986/6374/5539/259287/2852/50836/3339/1230/846/4886/2919/51764/94235/114/3708/5330/259290/6383/108/5196/3827/5173/2357/55970/2778/6352/140/10768/346562/152/5957/6364/80834/259292/3949/2793/5030/5697/5576/3355/5534/3351/4035/6288/6372/50834/259285/79823/1385/7804/5144/719/6363/2917/1268/50831/2359/50839/5660/1815/1325/1232/1902/50837/1269/59340/4887/2790/718/623 298 Influenza_A_virus R-HSA-9607240 FLT3 Signaling 214/4622 267/10654 1.3590035558461167e-35 6.332956570242904e-34 2.4843538687572875e-34 5295/5689/2674/4893/6711/1437/71/5682/1844/5291/5526/817/5908/3082/143471/2064/5705/8452/6776/4684/5709/9978/5695/2668/5605/5037/5711/3558/3717/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/3563/1741/9542/1739/2885/6709/8660/8826/9846/5518/2252/1740/4140/3845/5623/3265/4763/5696/5691/7314/5515/54106/5718/818/1839/5290/3667/8823/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/4902/2260/5528/3718/2249/25780/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/80824/1445/5710/5719/6233/2246/2251/5154/1843/6777/369/801/5781/30849/8682/1846/5170/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/409/5706/1438/673/2676/5140/8315/2263/4233/84078/5714/5688/5159/5687/5708/3084/5529/816/9693/208/6654/5704/10718/3716/7311/1956/60/5536/2549/5694/7529/5595/5516/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10817/10197/2254/7316/10213/152831/1950/3560/5289/3055/26281/10818/5715/2261/5701/27040/5685/2255/5686/2066/6708/27006/5979/1742/5527/5716/88/5906/5155/9048/4254/5296/3559/5693/5721/5245/5156/161742/284 214 Influenza_A_virus R-HSA-376176 Signaling by ROBO receptors 181/4622 218/10654 4.287072562984901e-34 1.9333314332428683e-32 7.584260799032712e-33 6158/5689/6138/6227/7852/6206/6234/6191/6128/5682/6132/57522/10298/6129/6176/5578/6224/6146/6154/26986/143471/6202/5705/6169/8829/23122/5709/6175/9978/6218/5695/65109/6173/6167/5711/1605/5683/6156/5699/6143/5702/6139/10487/3921/23332/5062/6208/5696/6170/5691/7314/5879/6387/5718/25/6203/6147/5700/122706/5707/5567/6222/23198/27/26019/2935/6134/6091/22794/6155/4116/6714/6231/9861/6142/23521/5698/5692/5713/1981/5710/6207/5719/6233/6188/5217/6122/80728/6230/6194/2107/9423/6166/56924/6136/6125/5706/6232/6160/55110/5714/6193/6210/6229/6205/5566/4650/5688/5687/5708/5063/140801/6235/6181/998/9939/6654/5704/7311/6223/25873/387/5694/5058/9045/6187/65110/6168/22916/6157/6137/10921/6144/55740/23032/5684/9349/4736/5720/51121/2817/6159/4690/6217/6152/5690/5717/9491/51065/6141/23053/10197/6164/4686/7316/10213/5216/6209/11224/6165/6130/5715/6204/5701/6228/5576/5685/51466/5686/7408/6124/8453/5716/6189/9775/6135/6201/6161/5693/5721/6133 181 Influenza_A_virus R-HSA-202403 TCR signaling 113/4622 119/10654 6.0105507159655785e-34 2.57486923732966e-32 1.0100947764842653e-32 5295/8454/5689/5335/4790/5682/5291/7321/143471/5705/3115/5709/5695/4792/3113/5711/3117/5683/5699/5702/26191/3127/7334/3551/5062/5696/5691/7314/5718/8945/3635/5290/5700/122706/5707/8767/23198/23118/10892/8517/3126/5970/9861/5588/5698/5692/5713/1445/5710/916/5719/6233/3702/3932/3120/5170/387522/3937/3123/5706/3122/920/8915/5714/5795/5688/5687/5708/5063/7189/7535/5704/7311/3125/5694/5058/997/1147/55740/9402/5684/5720/6885/4690/3119/84433/5690/5717/9491/6500/10197/919/7316/10213/7335/50852/7322/5715/5701/27040/23291/915/5685/917/51466/5686/7408/5728/7454/5716/5296/5693/5721 113 Influenza_A_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 124/4622 134/10654 6.078017513009926e-34 2.57486923732966e-32 1.0100947764842653e-32 5295/8454/5689/3725/4893/5335/4790/5682/5291/7321/143471/5705/5530/5709/5695/4792/5711/5683/2534/5699/5702/2885/9846/3845/7334/3265/3551/5062/5696/5691/7314/5879/7294/257397/5718/8945/5601/4773/5290/5700/122706/5707/5336/5594/4214/23198/23118/10892/8517/5970/9861/5588/5698/5692/5713/5710/10454/5719/6233/7410/7409/3702/2353/3710/801/5170/6464/2205/387522/4772/3937/10451/5706/2206/6850/8915/5714/5688/5687/4067/5708/5602/695/7189/6654/5704/7311/5694/5058/6416/997/5595/1147/9402/5684/5720/6885/84433/5690/5717/9491/6500/3708/10197/7316/10213/7335/10768/7462/7322/5715/5701/27040/23291/5685/5686/5534/5609/5716/5296/5599/5693/5721/2207 124 Influenza_A_virus R-HSA-162906 HIV Infection 190/4622 233/10654 1.2559369845257112e-33 5.16411736578513e-32 2.0258302443897694e-32 6884/23165/6875/5689/7852/162/5682/27243/6874/1174/348995/143471/57122/5705/5431/23511/5435/5709/9978/5433/5695/292/567/51271/23279/5711/23327/8732/23225/5683/2965/2534/27183/5699/5439/5702/6873/3836/163/9972/6881/51616/8021/1794/11198/51497/5062/55746/5696/5691/92421/7314/5879/5718/137492/8945/161/25978/5700/51160/122706/5707/2959/23198/91782/5438/10762/79720/4836/926/9397/9861/79902/9883/83860/51510/5698/5692/5713/5710/2068/5902/5478/5719/6233/7514/1025/3932/6396/129401/6883/1175/6829/8907/940/25920/60489/1173/4928/2963/5434/5903/55706/7175/5436/6878/4869/5706/160/293/920/4331/5714/4927/8148/2962/5688/54457/8812/5687/5708/128866/905/2071/5901/8086/5704/7311/93343/6880/6908/7251/8905/5694/1104/2547/6882/2961/5432/22916/1234/6877/5905/3837/81929/5440/164/5684/8065/5720/902/9631/3159/5430/5690/7520/5717/9491/6500/6749/79023/5441/23636/10197/919/4686/7316/10213/6872/53371/3055/9688/6879/9150/5715/5701/5437/5685/5686/2968/5716/9844/375/138474/1022/5693/5721/8178/8480/291 190 Influenza_A_virus R-HSA-2262752 Cellular responses to stress 335/4622 479/10654 2.9889129223817695e-33 1.1938572187113467e-31 4.683379346047826e-32 1912/23165/5689/3725/6782/9134/2077/11065/573/4790/5682/64344/7531/1915/7321/51807/817/6045/8697/9530/347688/23677/27327/80012/7295/5925/3091/348995/143471/472/10381/57122/5705/79813/3576/3313/1780/7001/23511/5709/9978/2114/1869/5695/3305/8655/84516/1911/832/23279/4194/1031/91582/5711/5928/1432/1387/4683/7846/259217/23225/5683/3309/23512/57332/5699/7428/5702/192669/9531/8900/51529/29945/8091/8131/2056/51434/2475/3306/27000/1030/6196/9972/23411/8021/4343/6117/6197/29882/3312/4217/54386/3569/55746/5696/5691/7296/7314/51164/996/51182/5718/818/3303/7014/6118/5601/79861/5606/7027/526/5700/122706/5707/2146/2936/9114/5594/3308/84335/23198/898/10049/10013/27244/3337/10762/847/7323/890/5970/9261/6667/51433/9861/79902/5598/9883/2932/84733/529/5698/5692/5713/2877/119504/10376/6195/5710/3301/10540/7157/7324/5719/64682/6233/2353/8726/6396/129401/5600/201163/26523/405/5608/3297/57521/140735/768/6015/84617/4928/1019/5903/83667/55706/7175/5241/11258/9448/246184/112399/1029/1783/25828/8535/84962/10382/93661/5931/10294/55860/830/7013/7277/1051/1410/50488/5706/10671/8881/6774/1639/5714/4927/7867/64223/6119/26353/3552/10370/10524/5688/57805/5687/3281/3310/2908/347733/5708/5602/7266/6009/51143/816/6648/8086/10393/5704/3326/51343/7311/367/25906/3397/2034/79400/57634/10383/84790/55662/648/5694/3304/23466/3456/2113/6416/10641/7280/10728/829/23523/5595/1778/1017/815/25913/81929/55846/5684/5720/9631/3159/7290/116835/10111/475/7422/5690/57690/5717/1027/9491/545/79023/23636/10197/192670/10808/8550/29855/4306/1781/7316/10213/10935/53371/1026/9532/54205/2289/9588/9688/10121/7415/1871/6647/8994/7322/5715/5701/112398/5685/3320/65057/5686/2033/1021/6767/25842/8453/23135/10963/22824/57600/23112/5609/10542/5716/9529/5599/54583/5052/96459/5693/5721/55466/2288/5034/8480/10919/4193/2950/23043 335 Influenza_A_virus R-HSA-5684996 MAPK1/MAPK3 signaling 203/4622 255/10654 5.059505747324637e-33 1.9647747318777343e-31 7.707609632620282e-32 5689/2674/4893/6711/1437/71/5682/1844/5526/817/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/2668/5605/5037/5711/3558/3717/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/3563/1741/9542/1739/2885/6709/8660/8826/5518/2252/1740/4140/3845/5623/3265/4763/3569/5696/5691/7314/3572/5515/5718/818/1839/3667/8823/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/4902/2260/5528/983/3718/2249/25780/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/80824/1445/5710/5719/6233/2246/2251/5154/1843/369/801/7297/5781/8682/1846/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/409/5706/1438/673/2676/8315/2263/4233/84078/5714/5688/5159/5687/5708/3084/5529/816/9693/6654/5704/10718/3716/7311/1956/60/5536/5694/7529/5595/5516/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10817/10197/2254/7316/10213/152831/1950/3560/26281/10818/5715/2261/5701/27040/5685/2255/5686/2066/6708/27006/5979/1742/5527/5716/88/5906/5155/9048/4254/3559/5693/5721/5245/5156/161742/284 203 Influenza_A_virus R-HSA-69618 Mitotic Spindle Checkpoint 107/4622 112/10654 6.562309837451996e-33 2.479488960204835e-31 9.726780726351323e-32 55839/11130/11065/6249/9735/7321/5526/8697/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/996/5515/79682/10403/25936/3619/64105/332/5528/51433/79902/3796/5519/81565/91687/119504/11243/7324/83540/64682/7514/54820/6396/64946/9793/140735/220134/4928/5903/246184/55055/80776/1783/401541/79172/79980/6232/8881/5501/54821/9183/1062/699/22919/5529/51143/10393/25906/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/100527963/55166/79003/5527/701/57551 107 Influenza_A_virus R-HSA-202424 Downstream TCR signaling 96/4622 98/10654 1.364143869285925e-32 5.018613498057166e-31 1.968750570354479e-31 5295/8454/5689/4790/5682/5291/7321/143471/5705/3115/5709/5695/4792/3113/5711/3117/5683/5699/5702/3127/7334/3551/5696/5691/7314/5718/8945/3635/5290/5700/122706/5707/8767/23198/23118/10892/8517/3126/5970/9861/5588/5698/5692/5713/5710/916/5719/6233/3932/3120/5170/387522/3123/5706/3122/920/8915/5714/5688/5687/5708/7189/5704/7311/3125/5694/997/1147/5684/5720/6885/3119/84433/5690/5717/9491/6500/10197/919/7316/10213/7335/50852/7322/5715/5701/23291/915/5685/917/5686/5728/5716/5296/5693/5721 96 Influenza_A_virus R-HSA-6807070 PTEN Regulation 127/4622 140/10654 1.78448875441206e-32 6.396705842738615e-31 2.5093620541125057e-31 1912/5689/3725/6591/5682/1822/1459/9112/6045/27327/80012/1460/143471/5705/5709/5695/1457/1911/4734/11060/5711/5928/5683/23512/57332/5699/2444/5702/192669/1107/8975/5371/2475/1386/4343/80351/5696/5691/23252/7314/5718/23186/5700/122706/5707/2146/51564/5594/84232/23198/9861/7101/81847/84733/57459/5698/10000/5692/5713/5710/3066/7157/5719/6233/331/8726/26523/7874/57521/23608/6015/9219/8535/5931/5706/8658/5714/1108/2122/64223/10014/5688/5687/5708/54815/6009/208/5704/57504/7311/648/5694/23466/53615/5595/27161/5684/8841/5720/5468/5978/10273/207/5690/57690/5717/9491/10197/192670/7316/10213/57167/5715/1958/5701/5685/5686/5728/6615/3065/23028/5987/23112/10542/5716/5693/5721 127 Influenza_A_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 91/4622 92/10654 3.161926790635198e-32 1.1050934133270018e-30 4.335168047160364e-31 6884/6875/5563/83990/9156/1763/1459/7486/6874/9212/5982/1460/11200/472/53632/28996/1457/6790/4194/1432/4683/84126/8900/6873/672/6881/51616/6117/11198/83695/7314/1263/6118/51422/116028/890/83860/5985/7157/5984/6233/5600/6883/5884/5810/26155/80010/8445/204851/6878/580/11073/641/8148/6119/3364/5571/10524/54457/144715/6794/94241/1111/7311/5562/6880/6908/5983/5564/6882/5565/1020/6877/1017/9891/5883/10111/22974/6749/545/8550/7316/6872/6879/112858/5932/8851/5300/7156/138474/4193 91 Influenza_A_virus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 148/4622 171/10654 3.2461093404922434e-32 1.1068441117093064e-30 4.342035857243797e-31 6158/5689/6138/6227/6206/6234/6191/6128/5682/6132/6129/6176/6224/6146/6154/26986/143471/6202/5705/6169/5709/6175/9978/6218/5695/65109/6173/6167/5711/1605/5683/6156/5699/6143/5702/6139/3921/6208/5696/6170/5691/7314/5718/6203/6147/5700/122706/5707/6222/23198/26019/2935/6134/6091/22794/6155/4116/6231/9861/6142/23521/5698/5692/5713/1981/5710/6207/5719/6233/6188/6122/6230/6194/2107/6166/6136/6125/5706/6232/6160/55110/5714/6193/6210/6229/6205/5688/5687/5708/140801/6235/6181/9939/5704/7311/6223/25873/5694/9045/6187/65110/6168/22916/6157/6137/10921/6144/23032/5684/9349/4736/5720/51121/6159/6217/6152/5690/5717/9491/51065/6141/23053/10197/6164/4686/7316/10213/6209/11224/6165/6130/5715/6204/5701/6228/5685/5686/6124/8453/5716/6189/9775/6135/6201/6161/5693/5721/6133 148 Influenza_A_virus R-HSA-5673001 RAF/MAP kinase cascade 198/4622 249/10654 4.179377205951895e-32 1.3911355556954165e-30 5.457282015791824e-31 5689/2674/4893/6711/1437/71/5682/1844/5526/817/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/2668/5605/5037/5711/3558/3717/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/3563/1741/9542/1739/2885/6709/8660/8826/5518/2252/1740/4140/3845/5623/3265/4763/5696/5691/7314/5515/5718/818/1839/3667/8823/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/4902/2260/5528/3718/2249/25780/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/80824/1445/5710/5719/6233/2246/2251/5154/1843/369/801/8682/1846/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/409/5706/1438/673/2676/8315/2263/4233/84078/5714/5688/5159/5687/5708/3084/5529/816/9693/6654/5704/10718/3716/7311/1956/60/5536/5694/7529/5595/5516/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10817/10197/2254/7316/10213/152831/1950/3560/26281/10818/5715/2261/5701/27040/5685/2255/5686/2066/6708/27006/5979/1742/5527/5716/88/5906/5155/9048/4254/3559/5693/5721/5245/5156/161742/284 198 Influenza_A_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 328/4622 473/10654 1.9398478742437635e-31 6.3067612283553054e-30 2.47407770497185e-30 5295/5777/627/3643/9252/4893/857/5335/71/5579/5770/5291/26469/5578/1785/5908/3082/51741/23385/2064/1289/5431/8829/6696/6776/5435/3688/5433/5753/4734/10413/5605/3910/8569/5898/1432/3717/145957/2534/9475/3690/9965/5439/2264/5603/3630/6456/83737/7072/4145/9542/30011/2885/2475/8660/6093/163/7073/6196/9846/1759/5518/2252/8874/9564/6197/3845/3265/1399/3071/8877/5062/23769/4486/10603/51231/5829/7314/5879/5515/6387/5607/54106/26999/1839/3918/161/5290/3667/5899/8823/2065/526/3815/5567/8027/10006/3911/1849/2060/9114/5594/2069/8074/284217/9101/23118/5921/6778/2260/5438/348/5528/9306/1500/3185/11059/102/9261/2249/6714/2099/5664/2248/5519/5598/4670/2567/4909/2321/2247/4914/529/10810/10000/9146/6455/2335/64759/6195/3728/8471/1445/3925/6233/7525/7410/5580/2324/7409/2246/23191/3685/2251/5154/3932/1213/3791/1729/3710/1211/29924/5600/6777/1175/6300/801/5781/30849/5663/5725/1291/10787/1846/253260/25920/5170/4908/1173/2963/5434/5590/6464/85440/5241/2904/6461/5747/5782/7424/5436/2322/7074/3315/2241/10451/4318/382/160/3912/1793/673/5140/6774/2263/4233/10152/6772/8651/26052/7867/64223/5566/5802/2962/1003/8503/5795/2889/10163/5159/4067/3084/55845/5063/1111/998/3481/208/6654/5867/10718/79109/5900/7311/2185/387/1956/60/2549/5058/1020/5432/3480/22916/11140/53916/4916/7529/63916/5595/5516/9402/5440/8065/685/23543/26018/558/4915/1495/5604/1499/4690/5430/10048/10273/207/7422/10458/3178/8817/10817/3708/5441/58513/2254/4686/7316/152831/1950/9611/9047/4205/5289/57498/10768/26281/10818/8936/23545/2261/867/5437/2255/3320/4846/4803/2066/3914/27006/6285/1742/1398/3187/5774/1385/9844/5228/5906/3479/5155/23163/4254/8851/5296/5581/581/10076/7059/7057/11033/10254/6457/5156/161742/2887/2242 328 Influenza_A_virus R-HSA-2500257 Resolution of Sister Chromatid Cohesion 116/4622 126/10654 2.874603996443693e-31 9.133400879609733e-30 3.582939430974077e-30 55839/11130/6249/9735/5526/51807/9212/347688/10274/147841/348995/10381/57122/1780/23122/5048/57405/8655/23279/2491/7846/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/79861/25936/55869/3619/64105/332/5528/983/79902/3796/5519/81565/91687/11243/10376/83540/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/55055/80776/1783/401541/10382/79172/7277/9133/79980/6232/23047/5885/891/5501/54821/9183/1062/699/347733/22919/8243/5529/51143/10383/5347/84790/84643/7280/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23244/23421/55920/79023/10735/1781/4085/100527963/55166/79003/9126/5527/701/57551 116 Influenza_A_virus R-HSA-5620912 Anchoring of the basal body to the plasma membrane 95/4622 98/10654 5.861708497113937e-31 1.821037439770063e-29 7.143742987125991e-30 79867/7531/11190/203068/54801/85302/79441/5116/5048/22832/8655/9702/132320/7846/7840/11064/84902/5518/55835/23332/93323/1454/54806/91147/983/79959/10540/117177/57545/26005/54930/54820/23322/1453/9793/4218/11258/22981/8636/54903/80776/7532/55125/10382/121441/7277/9814/23354/146057/9738/1639/55722/4957/5566/7283/22919/27077/22994/4867/1069/5577/10383/5347/80184/22897/5108/261734/57787/10806/9657/1778/115106/22995/55559/10142/51134/95681/1781/80321/8766/79598/10121/347240/84131/3320/79600/10733/4751/80254/26123/9662/55142/8481/51259/55755 95 Influenza_A_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 87/4622 88/10654 8.922182374678536e-31 2.711567599956651e-29 1.0637201412374183e-29 5393/5689/5682/23404/5578/26986/143471/5705/5709/5695/5711/1432/5683/5699/5702/11340/8021/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/7534/9261/8741/9861/5698/5692/5713/1981/5710/5719/6233/5580/7514/5600/8570/23016/118460/1994/5073/3842/3315/5706/8125/677/7538/5714/5688/5687/5708/5704/7311/51010/5694/56915/3304/6418/167227/7529/22894/5684/5720/207/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/55802/51013/5716/54464/5693/54512/5721 87 Influenza_A_virus R-HSA-8953897 Cellular responses to external stimuli 337/4622 493/10654 2.1104817854542364e-30 6.277560715031962e-29 2.4626226432735887e-29 1912/23165/5689/3725/6782/9134/2077/11065/573/4790/5682/64344/7531/1915/7321/51807/817/6045/8697/9530/347688/23677/27327/80012/7295/5925/3091/348995/143471/472/10381/57122/5705/79813/3576/3313/1780/7001/23511/5709/9978/2114/1869/5695/3305/8655/84516/1911/832/23279/4194/1031/91582/5711/5928/1432/1387/4683/7846/259217/23225/5683/3309/23512/57332/5699/7428/5702/192669/9531/8900/51529/29945/8091/8131/2056/51434/2475/3306/27000/1030/6196/9972/23411/8021/4343/6117/6197/29882/3312/4217/54386/3569/55746/5696/5691/7296/7314/51164/996/51182/5718/818/3303/7014/6118/5601/79861/5606/7027/526/5700/122706/5707/2146/2936/9114/5594/3308/84335/23198/898/10049/10013/27244/3337/10762/847/7323/890/5970/9261/6667/51433/9861/79902/5598/9883/2932/84733/529/5698/5692/5713/2877/119504/10376/6195/5710/3301/10540/7157/7324/5719/64682/6233/2353/8726/6396/129401/5600/201163/26523/405/5608/3297/57521/140735/768/6015/84617/4928/1019/5903/83667/55706/7175/5241/11258/9448/246184/112399/1029/1783/25828/8535/84962/10382/93661/5931/10294/55860/830/7013/7277/1051/1410/50488/5706/10671/8881/6774/1639/5714/4927/7867/64223/6119/26353/3552/10370/10524/5688/57805/5687/3281/3310/2908/347733/5708/5602/7266/6009/51143/816/6648/8086/10393/5704/3326/51343/7311/367/25906/3397/2034/79400/57634/10383/84790/55662/648/5694/3304/23466/3456/2113/6416/10641/7280/10728/829/23523/5595/1778/1017/815/25913/81929/55846/5684/5720/9631/3159/7290/116835/10111/475/4502/7422/5690/57690/5717/1027/9491/545/79023/23636/10197/192670/10808/8550/29855/4306/1781/7316/10213/10935/53371/1026/9532/54205/2289/9588/9688/10121/7415/1871/6647/8994/7322/5715/5701/112398/5685/3320/65057/5686/2033/1021/6767/25842/8453/23135/10963/22824/57600/23112/5609/10542/5716/9529/4520/5599/54583/5052/96459/5693/5721/55466/2288/5034/8480/10919/4193/2950/23043 337 Influenza_A_virus R-HSA-69242 S Phase 139/4622 161/10654 4.497263633110104e-30 1.3098280331433176e-28 5.138320949233255e-29 8454/5689/9134/11065/5682/1763/7321/8697/5982/10274/5925/143471/5705/5709/5422/9978/1869/4174/5753/5695/84515/4609/5711/5928/5683/5699/5702/8900/51529/29945/51434/6117/29882/5001/10714/7465/5696/5691/7314/996/5718/6118/7027/5700/122706/5707/23198/898/91768/5934/993/890/51433/9861/2932/6502/5698/10000/5692/5985/5713/119504/595/5710/5984/7324/5719/64682/6233/113130/23649/1163/5424/4172/1019/8318/246184/54107/4173/5706/286826/23047/8881/5885/4331/5425/5714/5111/6119/5688/5687/5427/5708/1874/8243/81620/10393/208/5704/55957/51343/7311/25906/5983/5694/4176/56655/1017/5684/994/5720/902/57804/207/5690/5717/1027/9491/6500/23244/10735/10197/4149/7316/10213/1026/5426/4171/5715/5701/5685/5686/9126/5716/114799/5981/1022/5693/5721 139 Influenza_A_virus R-HSA-162909 Host Interactions of HIV factors 117/4622 129/10654 5.537726278811948e-30 1.5799472117916538e-28 6.197970765329807e-29 23165/5689/162/5682/1174/348995/143471/57122/5705/23511/5709/9978/5695/292/567/23279/5711/23225/5683/2534/5699/5702/3836/163/9972/8021/1794/5062/55746/5696/5691/7314/5879/5718/8945/161/5700/122706/5707/23198/10762/926/9861/79902/9883/5698/5692/5713/5710/5902/5478/5719/6233/7514/1025/3932/6396/129401/1175/8907/940/60489/1173/4928/5903/55706/7175/4869/5706/160/293/920/5714/4927/5688/5687/5708/5901/8086/5704/7311/8905/5694/1104/5905/3837/81929/164/5684/8065/5720/9631/3159/5690/5717/9491/6500/79023/23636/10197/919/7316/10213/53371/3055/9688/5715/5701/5685/5686/5716/9844/375/5693/5721/8480/291 117 Influenza_A_virus R-HSA-9020702 Interleukin-1 signaling 98/4622 103/10654 8.810753132098087e-30 2.4634865757346252e-28 9.664005014364429e-29 8454/5689/4790/5682/8878/143471/5705/5709/9978/5695/4792/5711/5683/5699/5702/3654/51135/7334/3551/5696/5691/7314/257397/5718/8945/1326/11213/5700/122706/5707/8767/23198/23118/8517/5970/9861/5698/5692/5713/5710/10454/5719/6233/7850/5608/4791/3557/351/387522/54472/5706/79155/5714/64127/3552/5688/5687/5708/3656/57162/7189/5704/7311/5694/6416/3554/3556/1147/5684/5720/6885/5604/4215/10392/5690/3553/5717/9491/6500/246330/10197/4615/7316/10213/7335/4793/3146/5715/5701/23291/5685/5686/6288/6285/5716/57161/5693/5721 98 Influenza_A_virus R-HSA-5357801 Programmed Cell Death 151/4622 181/10654 4.5041179416327177e-29 1.234658212235792e-27 4.843437456327442e-28 5689/5682/4976/7531/356/10971/10059/7533/2810/143471/5705/5709/1869/5695/8655/660/5711/836/100302736/5683/929/324/5699/9414/5702/3836/6709/6093/7159/26060/637/5062/5696/5691/7314/578/23368/5718/2934/11035/22985/219699/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/100506658/7082/5339/4836/8797/9861/28988/10134/22900/999/5588/598/5698/10000/5692/708/5713/5710/3002/7157/5719/6233/5580/1613/839/8772/331/8717/57099/317/8743/140735/1828/5747/1029/572/7532/330/118/5706/6774/5366/5714/8428/5688/5687/5708/8837/8626/197259/208/5704/7311/7161/5694/8795/7529/5595/23643/4000/27113/3837/596/5684/5720/7186/51765/1499/10018/842/207/5690/5717/9491/355/10197/7099/7316/10213/54205/115209/3146/5715/23604/5701/329/5685/5686/5534/4137/5716/581/5599/353376/7431/5693/5721/148022 151 Influenza_A_virus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 84/4622 86/10654 2.697096767732306e-28 7.114228832622197e-27 2.7908389592622274e-27 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 84 Influenza_A_virus R-HSA-453276 Regulation of mitotic cell cycle 84/4622 86/10654 2.697096767732306e-28 7.114228832622197e-27 2.7908389592622274e-27 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 84 Influenza_A_virus R-HSA-109581 Apoptosis 148/4622 178/10654 3.359386597397704e-28 8.697078635485167e-27 3.411774692483828e-27 5689/5682/4976/7531/356/10971/10059/7533/2810/143471/5705/5709/1869/5695/8655/660/5711/836/100302736/5683/929/324/5699/9414/5702/3836/6709/6093/7159/26060/637/5062/5696/5691/7314/578/23368/5718/2934/22985/219699/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/100506658/7082/5339/4836/8797/9861/28988/10134/22900/999/5588/598/5698/10000/5692/708/5713/5710/3002/7157/5719/6233/5580/1613/839/8772/331/8717/57099/317/8743/140735/1828/5747/1029/572/7532/118/5706/6774/5366/5714/8428/5688/5687/5708/8837/8626/208/5704/7311/7161/5694/8795/7529/5595/23643/4000/27113/3837/596/5684/5720/7186/51765/1499/10018/842/207/5690/5717/9491/355/10197/7099/7316/10213/54205/115209/3146/5715/23604/5701/329/5685/5686/5534/4137/5716/581/5599/353376/7431/5693/5721/148022 148 Influenza_A_virus R-HSA-72613 Eukaryotic Translation Initiation 108/4622 119/10654 8.047586906047905e-28 2.009022588331245e-26 7.881189432426613e-27 6158/6138/6227/6206/1965/6234/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/8663/23521/8894/1981/6207/1977/6233/51386/6188/1978/6122/1968/6230/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/8893/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/8891/51121/6159/6217/6152/51065/6141/10480/1967/6164/9669/6209/11224/6165/6130/8890/6204/6228/6124/3646/6189/6135/6201/6161/8892/6133 108 Influenza_A_virus R-HSA-72737 Cap-dependent Translation Initiation 108/4622 119/10654 8.047586906047905e-28 2.009022588331245e-26 7.881189432426613e-27 6158/6138/6227/6206/1965/6234/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/8663/23521/8894/1981/6207/1977/6233/51386/6188/1978/6122/1968/6230/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/8893/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/8891/51121/6159/6217/6152/51065/6141/10480/1967/6164/9669/6209/11224/6165/6130/8890/6204/6228/6124/3646/6189/6135/6201/6161/8892/6133 108 Influenza_A_virus R-HSA-3371556 Cellular response to heat stress 86/4622 89/10654 8.89136277690792e-28 2.180723712652153e-26 8.554755321826457e-27 23165/6782/573/7531/1915/817/9530/348995/472/57122/3313/23511/3305/23279/91582/1387/259217/23225/3309/9531/2475/3306/27000/9972/23411/8021/6117/3312/55746/51182/818/3303/6118/5594/3308/84335/10049/10013/3337/10762/9261/79902/9883/2932/6396/129401/3297/57521/4928/5903/55706/7175/1410/4927/64223/6119/26353/57805/3281/3310/7266/816/8086/3326/3304/10728/5595/815/81929/9631/116835/545/79023/23636/10808/53371/9532/9688/7415/3320/2033/6767/22824/9529/2288/8480 86 Influenza_A_virus R-HSA-927802 Nonsense-Mediated Decay (NMD) 105/4622 115/10654 1.2582536468252593e-27 2.981421352985953e-26 1.1695809991007318e-26 6158/9887/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/65109/6173/6167/6156/6143/5520/6139/23381/5518/3921/6208/6170/5515/6203/6147/6222/26019/2935/6134/22794/6155/4116/6231/6142/23521/1981/6207/6233/6188/23049/5976/6122/6230/6194/2107/6166/6136/6125/6232/6160/55110/6193/6210/6229/6205/140801/6235/6181/9939/7311/6223/25873/9045/6187/65110/6168/22916/6157/6137/10921/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/4686/6209/11224/6165/6130/6204/6228/55802/6124/6189/23293/9775/6135/6201/6161/6133 105 Influenza_A_virus R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 105/4622 115/10654 1.2582536468252593e-27 2.981421352985953e-26 1.1695809991007318e-26 6158/9887/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/65109/6173/6167/6156/6143/5520/6139/23381/5518/3921/6208/6170/5515/6203/6147/6222/26019/2935/6134/22794/6155/4116/6231/6142/23521/1981/6207/6233/6188/23049/5976/6122/6230/6194/2107/6166/6136/6125/6232/6160/55110/6193/6210/6229/6205/140801/6235/6181/9939/7311/6223/25873/9045/6187/65110/6168/22916/6157/6137/10921/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/4686/6209/11224/6165/6130/6204/6228/55802/6124/6189/23293/9775/6135/6201/6161/6133 105 Influenza_A_virus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 85/4622 88/10654 2.0014887629202277e-27 4.6634688176041306e-26 1.8294309569849802e-26 8454/7531/11190/203068/54801/79441/5116/5048/8655/6790/9702/7846/7840/11064/5518/55835/23332/93323/7314/8945/4659/1454/983/79959/10540/6233/54930/54820/1453/9793/4218/5500/11258/22981/8636/7532/84962/55125/10382/121441/7277/9133/9814/23354/891/9738/1639/55722/4957/5566/7283/22919/22994/79866/1069/5577/7311/10133/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/6500/1781/7316/80321/10121/84131/23291/3320/10733/4751/80254/9662/55142/8481/55755 85 Influenza_A_virus R-HSA-141424 Amplification of signal from the kinetochores 91/4622 96/10654 2.3077268456012758e-27 5.203551822823521e-26 2.0412999771787177e-26 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/79902/3796/5519/81565/91687/11243/83540/7514/54820/6396/64946/9793/140735/220134/4928/5903/55055/80776/1783/401541/79172/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/100527963/55166/79003/5527/701/57551 91 Influenza_A_virus R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 91/4622 96/10654 2.3077268456012758e-27 5.203551822823521e-26 2.0412999771787177e-26 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/79902/3796/5519/81565/91687/11243/83540/7514/54820/6396/64946/9793/140735/220134/4928/5903/55055/80776/1783/401541/79172/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/100527963/55166/79003/5527/701/57551 91 Influenza_A_virus R-HSA-453279 Mitotic G1-G1/S phases 128/4622 149/10654 2.49059188101679e-27 5.526741983589639e-26 2.1680841604172892e-26 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/1031/5711/5928/10926/3717/5683/5699/5702/5520/8900/55388/1030/5518/6117/5001/7465/5696/5691/7314/5515/6241/5718/6118/25/7027/5700/5707/7153/898/91768/5934/993/890/983/6714/9861/5519/6502/5698/10000/5692/5713/595/5710/896/5719/6233/7298/23649/1719/1163/1859/4172/1019/8318/1029/54107/4173/5706/286826/891/4331/5714/5111/51053/6119/5688/5687/5427/4067/5708/1874/81620/208/5704/55957/7311/5694/4176/5516/56655/1017/894/5684/5720/902/8317/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1026/5933/5426/4171/1871/5715/5701/5685/5686/1021/3065/5716/1022/5693/5721/7083/1028 128 Influenza_A_virus R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 80/4622 82/10654 7.204968692132095e-27 1.5496224971693338e-25 6.079010022025623e-26 114791/10844/440145/7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/1454/983/79959/80097/10540/85378/54930/54820/1453/27229/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/728642/9738/1639/55722/4957/5566/7283/22919/984/10426/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 80 Influenza_A_virus R-HSA-380287 Centrosome maturation 80/4622 82/10654 7.204968692132095e-27 1.5496224971693338e-25 6.079010022025623e-26 114791/10844/440145/7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/1454/983/79959/80097/10540/85378/54930/54820/1453/27229/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/728642/9738/1639/55722/4957/5566/7283/22919/984/10426/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 80 Influenza_A_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 102/4622 112/10654 1.215162023179701e-26 2.573934103644276e-25 1.0097279331365618e-25 5295/8454/5689/5777/4893/4790/5579/5682/143471/5705/5530/5709/5695/4792/5711/5683/2534/5699/5702/30011/2885/4794/3845/3265/3551/973/933/5696/5691/7314/5718/8945/4773/5966/5700/122706/5707/5336/23198/10892/8517/5970/25780/9861/5698/5692/5713/5710/2280/5478/5719/6233/7409/3710/118788/801/4772/930/5706/7220/6850/8915/5714/5688/5687/4067/29760/5708/695/6654/5704/7311/5293/27071/5694/1147/5684/5720/6885/4690/640/84433/5690/5717/9491/6500/3708/10197/7316/10213/10768/4793/5715/5701/23291/5685/5686/5534/974/5716/5693/5721 102 Influenza_A_virus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 75/4622 76/10654 1.9549493135016447e-26 4.0791330451870143e-25 1.6002020303760518e-25 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 75 Influenza_A_virus R-HSA-5663220 RHO GTPases Activate Formins 121/4622 140/10654 2.0346622381261763e-26 4.183026189559404e-25 1.6409582446807086e-25 55839/11130/71/6249/9735/5526/51807/9212/347688/147841/348995/10381/57122/1780/23122/3688/5048/57405/8655/23279/2491/7846/1060/11004/1855/9184/5518/23332/25909/10726/81930/55746/5879/5515/79682/10403/79861/25936/1856/389/3619/64105/332/5528/6714/79902/3796/5519/81565/91687/11243/10376/83540/1857/7514/54820/29984/1729/5217/6396/64946/9793/140735/220134/84617/4928/5903/55055/80776/1783/401541/10382/79172/7277/79980/6232/5501/54821/9183/1062/699/347733/22919/5529/51143/998/10383/5347/387/60/84790/84643/7280/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/5216/100527963/81624/55166/51466/79003/5527/701/57551 121 Influenza_A_virus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 78/4622 80/10654 3.7146232568662355e-26 7.526149729128981e-25 2.952431299507718e-25 8454/5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 78 Influenza_A_virus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 74/4622 75/10654 4.4881271404481865e-26 8.963431060495092e-25 3.516262015298504e-25 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 74 Influenza_A_virus R-HSA-909733 Interferon alpha/beta signaling 69/4622 69/10654 7.066330184795933e-26 1.3913703659640444e-24 5.458203152377585e-25 3443/5777/3442/5770/3107/9021/11274/3662/3106/4599/684/3133/3429/91543/4938/5696/3445/10410/9636/2634/3444/103/3434/3433/3447/3451/3448/3661/3439/10581/3452/4940/3437/6773/7297/5781/3430/3660/3446/3135/3665/10379/3455/4600/8638/3394/3663/6772/8651/3659/25939/3440/3454/3716/3456/3105/3441/51447/54739/2537/3449/8519/3664/6041/1958/4939/6059/3669/3134 69 Influenza_A_virus R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 101/4622 112/10654 1.5139672192850987e-25 2.9396196841119e-24 1.1531826334028311e-24 6158/6138/6227/6206/1965/6234/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/6202/6169/6175/6218/6173/6167/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/8663/23521/8894/1981/6207/1977/6233/51386/6188/6122/1968/6230/6194/6166/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6164/9669/6209/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 101 Influenza_A_virus R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 88/4622 94/10654 2.2406816795414168e-25 4.291058887669727e-24 1.683338363433422e-24 114791/10844/440145/7531/11190/203068/54801/51807/347688/79441/10381/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/79861/1454/983/79959/80097/10376/10540/85378/54930/54820/1453/27229/9793/84617/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/9738/1639/55722/4957/5566/7283/347733/22919/10426/22994/1069/5577/10383/5347/84790/80184/22897/5108/7280/10806/1778/115106/4926/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 88 Influenza_A_virus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72/4622 73/10654 2.3633723934981087e-25 4.4648575758248054e-24 1.7515178051387124e-24 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/5716/701/5693/5721 72 Influenza_A_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 93/4622 101/10654 2.6785762261607776e-25 4.99286608556369e-24 1.9586501246733544e-24 8454/5689/4790/5682/7321/9039/29108/143471/5705/5530/5709/5695/4792/5711/5683/5699/5702/7334/3551/5696/5691/7314/257397/5718/8945/4773/5700/122706/5707/5336/23198/23118/10892/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/3710/801/4791/5170/387522/4772/5706/6850/8915/5714/5688/5687/5708/7189/5704/7311/5971/5694/997/1147/5684/5720/6885/84433/5690/3553/5717/9491/6500/3708/10197/7316/10213/7335/10768/7322/5715/5701/23291/5685/5686/5534/5716/5693/5721 93 Influenza_A_virus R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 100/4622 111/10654 3.1859097559492366e-25 5.860397156338201e-24 2.298973660456444e-24 6158/6138/6227/6206/1965/6234/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/6156/6143/1973/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/8663/23521/8894/1981/6207/1977/6233/51386/6188/6122/1968/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6164/6209/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 100 Influenza_A_virus R-HSA-983169 Class I MHC mediated antigen processing & presentation 258/4622 371/10654 3.7228555047933544e-25 6.759158435975467e-24 2.6515484866675842e-24 8454/8773/5689/127544/11065/9666/55070/5682/3107/7321/65264/9021/10484/8697/26235/9817/9039/154881/811/143471/5705/57674/10333/9690/8452/5709/9978/5695/567/4734/7337/3693/84676/7704/3106/3093/10489/5711/23327/10616/5683/929/3309/25898/5699/7328/9632/7428/5702/22954/401036/83737/51529/140461/10075/29945/79176/8924/56658/51434/6468/10425/25793/23295/3133/51666/90293/54461/29882/7334/55182/4591/3551/7332/5696/5691/9820/7314/996/5718/197131/8945/64410/51320/5700/122706/5707/23198/10533/140462/51130/8517/7323/10517/22872/84861/7096/11059/27252/51444/26118/51433/9861/55905/10134/6502/5698/5692/5713/9903/26190/79654/5710/9040/7324/5719/64682/51191/6233/3685/26091/6047/868/6396/127247/5930/26268/115290/51725/140459/23608/55585/899/3135/23352/26224/246184/142686/387522/151636/10802/6890/821/2209/144699/5706/200845/79876/26263/9554/8881/7326/57630/29927/7317/80196/84078/5714/26272/8651/64219/5688/55336/5687/26270/63893/118424/5708/55008/2923/10422/695/90933/63891/9246/10393/5704/9870/9520/7327/51343/7311/9871/7318/9320/26232/57520/5694/8673/3105/997/7325/140691/23643/57154/1147/5684/79754/6737/8065/5720/84708/7319/54850/991/84231/10273/7320/5690/223082/5717/9491/6500/26259/10197/53339/7099/7336/4615/64750/51619/54778/7316/10213/7335/222235/25831/7322/5715/9867/5701/9341/23291/5685/5686/55521/114609/55294/135892/8453/80176/8139/126433/26267/5716/90025/7064/3134/80204/27338/7097/23014/90678/5693/5721/51676/10427/642 258 Influenza_A_virus R-HSA-156842 Eukaryotic Translation Elongation 87/4622 93/10654 4.8879451810334025e-25 8.760701747544483e-24 3.4367333863946054e-24 6158/6138/6227/6206/6234/6191/6128/6132/1917/6129/1915/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/6122/6230/6194/6166/1938/6136/6125/1937/6232/6160/1933/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/1936/6152/51065/6141/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 87 Influenza_A_virus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 71/4622 72/10654 5.420825052507278e-25 9.47289177925647e-24 3.716118226784594e-24 5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 71 Influenza_A_virus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 71/4622 72/10654 5.420825052507278e-25 9.47289177925647e-24 3.716118226784594e-24 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 71 Influenza_A_virus R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 96/4622 106/10654 1.1033150016089113e-24 1.9042399657398246e-23 7.470137957611993e-24 85439/8674/4738/1212/23208/950/554/10980/22848/7037/3482/408/10987/6456/185/30011/2885/163/11037/23149/9185/7314/9856/1839/161/7018/25977/10618/8027/1856/9892/8322/2060/2069/1601/6453/55707/8301/1129/9146/6455/4074/26119/29979/6233/90019/7474/6844/1213/1211/29924/4036/1175/85021/6869/1173/6857/84251/29988/409/160/338/8218/920/22905/2873/7311/1956/8533/8673/50618/51138/9318/685/127833/1080/29978/58513/7316/1950/3267/3949/867/9341/915/917/6572/115548/143425/3575/6845/551/154/10254/6457/50813 96 Influenza_A_virus R-HSA-69206 G1/S Transition 113/4622 131/10654 1.3653756678875143e-24 2.3277990045204204e-23 9.131716597809948e-24 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/5711/5928/10926/5683/5699/5702/8900/55388/5518/6117/5001/7465/5696/5691/7314/5515/6241/5718/6118/7027/5700/5707/898/91768/5934/993/890/983/9861/5519/6502/5698/10000/5692/5713/595/5710/5719/6233/7298/23649/1719/1163/4172/1019/8318/54107/4173/5706/286826/891/4331/5714/5111/51053/6119/5688/5687/5427/5708/1874/81620/208/5704/55957/7311/5694/4176/5516/56655/1017/5684/5720/902/8317/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1026/5933/5426/4171/5715/5701/5685/5686/3065/5716/1022/5693/5721/7083 113 Influenza_A_virus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 88/4622 95/10654 1.7507212497331517e-24 2.948805189309573e-23 1.1567860128230465e-23 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/26986/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/6208/6170/6203/6147/6222/2935/6134/6155/6231/6142/23521/1981/6207/6233/6188/5976/6122/6230/6194/2107/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/22916/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/4686/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 88 Influenza_A_virus R-HSA-2219528 PI3K/AKT Signaling in Cancer 92/4622 101/10654 3.715214189017299e-24 6.183177900293075e-23 2.4255972336817198e-23 5295/2308/5291/3082/941/2064/145957/2534/9965/2264/9542/2885/2475/8660/2252/5879/1839/5290/3667/8823/2065/3815/2069/84335/8074/7249/2260/2249/6714/2099/2248/2932/2247/5880/10000/7409/2246/2251/5154/3932/2931/118788/5781/940/253260/5170/572/4303/930/6199/2263/4233/64223/8503/5159/29851/3084/208/10718/79109/5293/1956/2549/1147/685/2309/842/207/1027/8817/2100/2254/152831/1950/1026/50852/26281/10818/2261/2255/3164/391/5728/2066/27006/942/1385/5155/4254/5296/5156/4193 92 Influenza_A_virus R-HSA-2871837 FCERI mediated NF-kB activation 78/4622 82/10654 6.817092849182627e-24 1.1212112709596838e-22 4.398396748512878e-23 8454/5689/4790/5682/7321/143471/5705/5709/5695/4792/5711/5683/5699/5702/7334/3551/5696/5691/7314/257397/5718/8945/5700/122706/5707/23198/23118/10892/8517/5970/9861/5588/5698/5692/5713/5710/10454/5719/6233/5170/2205/387522/5706/2206/8915/5714/5688/5687/4067/5708/7189/5704/7311/5694/997/1147/5684/5720/6885/84433/5690/5717/9491/6500/10197/7316/10213/7335/7322/5715/5701/23291/5685/5686/5716/5693/5721/2207 78 Influenza_A_virus R-HSA-199418 Negative regulation of the PI3K/AKT network 98/4622 110/10654 7.42076709514529e-24 1.2063060929085015e-22 4.732215001922517e-23 5295/3643/23035/5291/5526/3082/941/2064/145957/2534/9965/2264/3630/3654/9542/2885/8396/51135/8660/5518/2252/5879/5515/23396/1839/5290/3667/8823/90865/2065/3815/5594/2069/8074/79837/8395/2260/5528/2249/6714/2099/2248/5519/2247/5880/10000/7409/2246/2251/5154/3932/118788/8394/5781/940/23239/930/2263/4233/8503/5159/29851/3084/5529/7189/208/10718/5293/1956/2549/5595/3556/5516/685/5305/5525/207/8817/4615/2100/2254/152831/1950/50852/26281/10818/2261/2255/391/5728/2066/27006/942/5527/5155/4254/5296/5156 98 Influenza_A_virus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 93/4622 103/10654 1.0363299873308747e-23 1.6652750830903021e-22 6.532703247421484e-23 5295/3643/5291/5526/3082/941/2064/145957/2534/9965/2264/3630/3654/9542/2885/8396/51135/8660/5518/2252/5879/5515/23396/1839/5290/3667/8823/90865/2065/3815/5594/2069/8074/79837/8395/2260/5528/2249/6714/2099/2248/5519/2247/5880/7409/2246/2251/5154/3932/118788/8394/5781/940/930/2263/4233/8503/5159/29851/3084/5529/7189/10718/5293/1956/2549/5595/3556/5516/685/5305/5525/207/8817/4615/2100/2254/152831/1950/50852/26281/10818/2261/2255/391/2066/27006/942/5527/5155/4254/5296/5156 93 Influenza_A_virus R-HSA-156902 Peptide chain elongation 83/4622 89/10654 1.097414185958134e-23 1.7238034067072712e-22 6.762303854336935e-23 6158/6138/6227/6206/6234/6191/6128/6132/6129/1915/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/6122/6230/6194/6166/1938/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 83 Influenza_A_virus R-HSA-192823 Viral mRNA Translation 83/4622 89/10654 1.097414185958134e-23 1.7238034067072712e-22 6.762303854336935e-23 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/6188/6122/6230/6194/6166/6136/6125/6232/6160/5611/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/2926/51121/6159/6217/6152/51065/6141/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 83 Influenza_A_virus R-HSA-8854518 AURKA Activation by TPX2 71/4622 73/10654 1.1396039444733361e-23 1.7701847937485821e-22 6.944253275679628e-23 7531/11190/203068/54801/79441/5116/5048/8655/6790/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/22974/3161/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 71 Influenza_A_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 80/4622 85/10654 1.358446323583822e-23 2.086931824582619e-22 8.186819370586135e-23 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/91768/5934/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/1163/1019/5706/286826/4331/5714/5688/5687/5708/1874/208/5704/55957/51343/7311/5694/1017/5684/994/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1026/5715/5701/5685/5686/5716/1022/5693/5721 80 Influenza_A_virus R-HSA-69306 DNA Replication 109/4622 127/10654 2.2339419609176816e-23 3.3946205014814335e-22 1.3316747844829659e-22 8454/5689/9134/11065/5682/1763/7321/8697/5982/143471/5705/5709/5422/9978/1869/4174/5695/84515/5711/10926/5683/5699/5702/8900/51529/29945/51434/55388/6117/29882/5001/10714/5696/5691/7314/996/5718/6118/5700/122706/5707/23198/898/890/51433/9861/6502/5698/5692/5985/5713/119504/5710/5984/7324/5719/64682/6233/23649/5424/4172/8318/246184/54107/4173/5706/8881/5425/5714/5111/51053/6119/5688/5687/5427/5708/81620/10393/5704/51343/7311/25906/5983/5694/4176/56655/1017/5684/5720/57804/8317/5690/5717/9491/6500/10197/7316/10213/5426/4171/1871/5715/5701/5685/5686/5716/5981/5693/5721 109 Influenza_A_virus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 70/4622 72/10654 2.5774194177835405e-23 3.8744433828617093e-22 1.5199043765310975e-22 5689/9134/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/898/890/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/1017/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 70 Influenza_A_virus R-HSA-168898 Toll-like Receptor Cascades 127/4622 155/10654 3.302542935974394e-23 4.911654281374684e-22 1.9267915673490027e-22 8454/3725/10695/9252/4790/7321/1785/6280/10333/4792/1432/100302736/929/3654/51135/6196/1759/5518/7187/1386/6197/64145/7334/3551/51231/7314/5515/257397/54106/11035/8945/1326/5601/5606/11213/8737/8767/5336/1849/29110/5594/6271/4214/23118/841/8517/5528/7323/5970/7096/9261/5519/5598/6195/10454/3661/6233/51311/10010/2353/8772/5600/5781/30849/5608/4791/1508/1846/3665/351/81793/387522/7184/8411/330/51295/7098/338/79155/6279/8651/26052/7867/64127/5602/3656/57162/695/7189/81622/7311/9641/6416/51284/5595/5516/23643/1147/6885/5604/10392/6500/246330/7099/4615/7100/7316/7335/4205/5289/4793/5641/5775/3146/7322/329/23291/114609/6288/6285/5609/1385/5599/353376/7097/57161/148022 127 Influenza_A_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 76/4622 80/10654 3.3389177907477e-23 4.913481127858194e-22 1.9275082204759574e-22 3839/23165/201626/5335/348995/317649/57122/11274/23511/4734/23279/8672/23225/1973/3836/4599/9972/8021/7334/4938/55746/7314/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/1977/51191/6233/5610/4940/6396/129401/4928/3838/5903/55706/7175/2316/4600/8638/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/7318/1974/5595/3837/81929/9631/79023/23636/7316/53371/9688/6041/4939/6059/5300/9775/5495/8480 76 Influenza_A_virus R-HSA-1169091 Activation of NF-kappaB in B cells 66/4622 67/10654 3.424823888458084e-23 4.935983294911754e-22 1.9363355896762474e-22 8454/5689/4790/5579/5682/143471/5705/5709/5695/4792/5711/5683/5699/5702/4794/3551/5696/5691/7314/5718/8945/5966/5700/122706/5707/23198/10892/8517/5970/9861/5698/5692/5713/5710/5719/6233/5706/8915/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/84433/5690/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5716/5693/5721 66 Influenza_A_virus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 66/4622 67/10654 3.424823888458084e-23 4.935983294911754e-22 1.9363355896762474e-22 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 66 Influenza_A_virus R-HSA-72689 Formation of a pool of free 40S subunits 91/4622 101/10654 4.587446007619402e-23 6.544132161889718e-22 2.567195886111395e-22 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/8668/6224/6146/6154/8662/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/8665/6208/6170/6203/6147/8666/6222/8667/6134/6155/6231/6142/8663/23521/6207/6233/51386/6188/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/8664/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/10480/6164/6209/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 91 Influenza_A_virus R-HSA-69202 Cyclin E associated events during G1/S transition 78/4622 83/10654 6.516371406380145e-23 9.20190628900954e-22 3.609813400025577e-22 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/91768/5934/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/1163/1019/5706/286826/4331/5714/5688/5687/5708/1874/208/5704/55957/7311/5694/1017/5684/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1026/5715/5701/5685/5686/5716/1022/5693/5721 78 Influenza_A_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 88/4622 97/10654 7.50516464072598e-23 1.049222016773492e-21 4.1159902924402485e-22 8454/3725/9252/4790/4792/1432/100302736/929/3654/51135/6196/5518/1386/6197/64145/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/6195/10454/6233/51311/2353/5600/30849/5608/4791/1846/3665/351/387522/8411/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/5595/5516/23643/1147/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/5289/4793/3146/23291/6288/6285/5609/1385/5599/353376/57161/148022 88 Influenza_A_virus R-HSA-69239 Synthesis of DNA 103/4622 119/10654 9.01230103656523e-23 1.2474452325859596e-21 4.893599624857202e-22 8454/5689/9134/11065/5682/1763/7321/8697/5982/143471/5705/5709/5422/9978/4174/5695/84515/5711/5683/5699/5702/8900/51529/29945/51434/6117/29882/5001/10714/5696/5691/7314/996/5718/6118/5700/122706/5707/23198/898/890/51433/9861/6502/5698/5692/5985/5713/119504/5710/5984/7324/5719/64682/6233/23649/5424/4172/8318/246184/54107/4173/5706/8881/5425/5714/5111/6119/5688/5687/5427/5708/81620/10393/5704/51343/7311/25906/5983/5694/4176/56655/1017/5684/5720/57804/5690/5717/9491/6500/10197/7316/10213/5426/4171/5715/5701/5685/5686/5716/5981/5693/5721 103 Influenza_A_virus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 218/4622 309/10654 1.1320505734832984e-22 1.5515751977741678e-21 6.086670266096992e-22 8454/5689/127544/11065/9666/55070/5682/7321/65264/9021/8697/26235/9817/9039/154881/143471/5705/57674/9690/8452/5709/9978/5695/4734/7337/84676/7704/3093/10489/5711/23327/10616/5683/25898/5699/7328/7428/5702/22954/401036/83737/51529/140461/10075/29945/79176/8924/56658/51434/6468/10425/25793/23295/51666/90293/54461/29882/7334/55182/4591/7332/5696/5691/9820/7314/996/5718/197131/8945/64410/51320/5700/122706/5707/23198/10533/140462/51130/7323/10517/84861/11059/27252/51444/26118/51433/9861/55905/6502/5698/5692/5713/9903/26190/79654/5710/9040/7324/5719/64682/51191/6233/26091/6047/868/127247/5930/26268/115290/51725/140459/23608/55585/899/23352/26224/246184/142686/387522/151636/144699/5706/200845/79876/26263/8881/7326/57630/7317/80196/84078/5714/26272/8651/64219/5688/55336/5687/26270/63893/118424/5708/55008/10422/90933/63891/9246/10393/5704/9870/9520/7327/51343/7311/7318/9320/26232/57520/5694/997/7325/140691/57154/5684/79754/6737/8065/5720/84708/7319/54850/991/84231/10273/7320/5690/223082/5717/9491/6500/26259/10197/53339/7336/64750/51619/54778/7316/10213/7335/222235/25831/7322/5715/9867/5701/23291/5685/5686/55521/55294/135892/8453/80176/8139/126433/26267/5716/90025/7064/80204/27338/23014/90678/5693/5721/51676/642 218 Influenza_A_virus R-HSA-380259 Loss of Nlp from mitotic centrosomes 68/4622 70/10654 1.3163790528673568e-22 1.7695172268351584e-21 6.941634479189199e-22 7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 68 Influenza_A_virus R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 68/4622 70/10654 1.3163790528673568e-22 1.7695172268351584e-21 6.941634479189199e-22 7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 68 Influenza_A_virus R-HSA-166166 MyD88-independent TLR4 cascade 89/4622 99/10654 2.0211192340616989e-22 2.665589329451184e-21 1.0456833375830636e-21 8454/3725/9252/4790/7321/4792/1432/100302736/929/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/1326/5601/5606/8737/8767/1849/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/1846/3665/351/387522/330/79155/7867/64127/5602/3656/7189/7311/9641/6416/5595/5516/23643/1147/6885/5604/10392/6500/7099/7316/7335/4205/4793/3146/7322/329/23291/6288/6285/5609/1385/5599/353376/148022 89 Influenza_A_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 89/4622 99/10654 2.0211192340616989e-22 2.665589329451184e-21 1.0456833375830636e-21 8454/3725/9252/4790/7321/4792/1432/100302736/929/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/1326/5601/5606/8737/8767/1849/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/1846/3665/351/387522/330/79155/7867/64127/5602/3656/7189/7311/9641/6416/5595/5516/23643/1147/6885/5604/10392/6500/7099/7316/7335/4205/4793/3146/7322/329/23291/6288/6285/5609/1385/5599/353376/148022 89 Influenza_A_virus R-HSA-8948751 Regulation of PTEN stability and activity 67/4622 69/10654 2.9725975777504895e-22 3.883823751116995e-21 1.5235841987289771e-21 5689/5682/1459/1460/143471/5705/5709/5695/1457/4734/11060/5711/5683/5699/2444/5702/8975/80351/5696/5691/23252/7314/5718/5700/122706/5707/23198/9861/81847/5698/10000/5692/5713/5710/5719/6233/331/23608/5706/8658/5714/5688/5687/5708/208/5704/7311/5694/5684/5720/10273/207/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5728/5987/5716/5693/5721 67 Influenza_A_virus R-HSA-3858494 Beta-catenin independent WNT signaling 120/4622 146/10654 3.181013425887994e-22 4.117645156843904e-21 1.6153099365376659e-21 2788/5689/5579/5682/5331/5578/1212/5582/27327/143471/5705/5530/5709/5695/5881/5711/5683/5699/2782/5702/192669/57216/1855/163/4343/5593/3845/5696/5691/4920/7314/5879/2787/5718/161/51701/5700/122706/5707/1856/8322/23198/10681/2792/9861/5698/5880/5692/5713/2785/2783/2784/5710/5719/6233/7474/1857/1213/3710/1211/7855/1175/26523/801/2791/7976/1173/4772/409/5706/160/5714/6934/5688/5687/23236/5708/2786/5704/7311/387/5694/57154/27161/815/5684/5720/54331/6885/1499/59345/5690/57690/5717/9491/51764/94235/3708/5330/10197/192670/64750/7316/10213/55970/54361/5216/5715/5701/2793/5685/5686/5534/23112/23513/5716/5693/5721/6259/2790 120 Influenza_A_virus R-HSA-72202 Transport of Mature Transcript to Cytoplasm 78/4622 84/10654 5.2534364253196575e-022 6.737893690455855e-21 2.6432065452356755e-21 23165/8683/6431/84271/199746/348995/57122/23511/81608/65109/23279/23225/9877/9972/8021/55746/7919/53981/6432/8563/6430/80145/10762/22794/9785/11338/29107/4116/79902/9883/51213/10250/26097/51362/1977/57187/6396/129401/79228/2733/84324/4928/5903/55706/7175/6428/10212/55110/84321/6429/4927/10898/10569/9295/10482/51692/8086/9939/6426/22916/10921/81929/9631/29894/79023/23636/4686/8189/53371/7307/9688/9984/10189/9775/84248/6427/8480/55339 78 Influenza_A_virus R-HSA-69615 G1/S DNA Damage Checkpoints 66/4622 68/10654 6.70897291574878e-22 8.526494669287994e-21 3.3448563532106357e-21 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/993/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/1111/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 66 Influenza_A_virus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 62/4622 63/10654 9.384903452288195e-22 1.1819905429098105e-20 4.636827594729397e-21 5689/11065/5682/7321/8697/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/5707/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 62 Influenza_A_virus R-HSA-69052 Switching of origins to a post-replicative state 82/4622 90/10654 1.1302803485230325e-21 1.4047727413672893e-20 5.5107792956280234e-21 8454/5689/9134/11065/5682/7321/8697/143471/5705/5709/9978/4174/5695/84515/5711/5683/5699/5702/8900/51529/29945/51434/29882/5001/5696/5691/7314/996/5718/5700/122706/5707/23198/898/890/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/4172/246184/4173/5706/8881/5714/5688/5687/5708/81620/10393/5704/51343/7311/25906/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 82 Influenza_A_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 77/4622 83/10654 1.135474390375563e-21 1.4047727413672893e-20 5.5107792956280234e-21 8454/5689/4893/4790/5579/5682/143471/5705/5530/5709/5695/4792/5711/5683/5699/5702/4794/3845/3265/3551/5696/5691/7314/5718/8945/4773/5966/5700/122706/5707/23198/10892/8517/5970/25780/9861/5698/5692/5713/5710/2280/5478/5719/6233/801/4772/5706/8915/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/84433/5690/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5534/5716/5693/5721 77 Influenza_A_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 84/4622 93/10654 1.4885269887003738e-21 1.8095310697418457e-20 7.0986046783789e-21 8454/3725/9252/4790/4792/1432/100302736/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/6195/10454/6233/51311/2353/5600/5608/4791/1846/3665/351/387522/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/5595/5516/23643/1147/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/23291/6288/6285/5609/1385/5599/353376/57161/148022 84 Influenza_A_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 84/4622 93/10654 1.4885269887003738e-21 1.8095310697418457e-20 7.0986046783789e-21 8454/3725/9252/4790/4792/1432/100302736/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/6195/10454/6233/51311/2353/5600/5608/4791/1846/3665/351/387522/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/5595/5516/23643/1147/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/23291/6288/6285/5609/1385/5599/353376/57161/148022 84 Influenza_A_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 108/4622 129/10654 2.2452204265422283e-21 2.7058777209534784e-20 1.0614880600984583e-20 8454/3725/9252/4790/7321/1785/10333/4792/1432/100302736/929/3654/51135/6196/1759/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/1326/5601/5606/11213/8737/8767/5336/1849/29110/5594/4214/23118/841/8517/5528/7323/5970/7096/9261/5519/5598/6195/10454/3661/6233/10010/2353/8772/5600/5781/5608/4791/1846/3665/351/387522/330/51295/79155/8651/26052/7867/64127/5602/3656/57162/695/7189/7311/9641/6416/5595/5516/23643/1147/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/5775/3146/7322/329/23291/114609/6288/6285/5609/1385/5599/353376/7097/57161/148022 108 Influenza_A_virus R-HSA-5687128 MAPK6/MAPK4 signaling 81/4622 89/10654 2.398216445632259e-21 2.865561188883674e-20 1.1241302457709466e-20 2308/5689/2118/3725/5682/27327/143471/5705/5709/5695/4609/5711/5683/5699/5702/192669/4343/5062/5696/5691/7314/5879/5718/5700/122706/5707/5567/23198/3337/983/9861/5698/5692/5713/5710/8555/896/5719/6233/7514/26523/3315/5706/5597/5714/5566/5688/5687/5708/5063/998/5704/7311/5694/5058/27161/5684/5720/2309/10642/5690/57690/5717/9491/10197/192670/5596/8550/7316/10213/5715/5701/5685/5686/8556/23112/5716/5896/8202/5693/5721 81 Influenza_A_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 83/4622 92/10654 3.1317368152637445e-21 3.71031192181247e-20 1.4555172888067894e-20 8454/3725/9252/4790/4792/1432/100302736/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/54106/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/6195/10454/6233/51311/2353/5600/5608/4791/1846/351/387522/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/51284/5595/5516/23643/1147/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/23291/6288/6285/5609/1385/5599/353376/57161/148022 83 Influenza_A_virus R-HSA-69563 p53-Dependent G1 DNA Damage Response 64/4622 66/10654 3.411682809542158e-21 3.9746104731166144e-20 1.5591988980451442e-20 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Influenza_A_virus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 64/4622 66/10654 3.411682809542158e-21 3.9746104731166144e-20 1.5591988980451442e-20 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Influenza_A_virus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 72/4622 77/10654 7.039413463910528e-21 8.133140514501585e-20 3.190547555195638e-20 5689/5682/51807/63943/347688/143471/10381/5705/5709/5695/5711/7846/5683/5699/5702/5696/5691/7314/5718/79861/5700/122706/5707/23198/983/9861/5698/5692/5713/10376/5710/7157/5719/6233/84617/51512/10382/7277/5706/9133/891/5714/5688/5687/347733/5708/22919/5704/3326/7311/10383/5347/84790/5694/7280/5684/5720/5690/5717/9491/10197/7316/10213/1026/5715/5701/5685/3320/5686/5716/5693/5721 72 Influenza_A_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 84/4622 94/10654 8.056496257308461e-21 9.231952268620679e-20 3.6216001294717075e-20 8454/3725/9252/4790/7321/4792/1432/3654/6196/5518/7187/1386/6197/7334/3551/51231/7314/5515/257397/11035/8945/1326/5601/5606/8737/8767/1849/29110/5594/23118/841/8517/5528/7323/5970/9261/5519/5598/6195/10454/3661/6233/10010/2353/8772/5600/5608/4791/1846/3665/351/387522/330/7098/79155/7867/64127/5602/3656/7189/7311/9641/6416/5595/5516/1147/6885/5604/10392/6500/7316/7335/4205/4793/3146/7322/329/23291/6288/6285/5609/1385/5599/148022 84 Influenza_A_virus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 66/4622 69/10654 8.890923035171118e-21 1.0105293010706685e-19 3.964202739686908e-20 23165/6782/573/7531/9530/348995/472/57122/3313/23511/3305/23279/91582/259217/23225/3309/9531/3306/27000/9972/23411/8021/6117/3312/55746/51182/3303/6118/5594/3308/10049/3337/10762/9261/79902/9883/2932/6396/129401/3297/4928/5903/55706/7175/4927/6119/57805/3310/7266/8086/3304/5595/81929/9631/116835/545/79023/23636/10808/53371/9532/9688/6767/22824/9529/8480 66 Influenza_A_virus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 59/4622 60/10654 1.1196764814832132e-20 1.2522461768908255e-19 4.912433236654772e-20 8454/5689/9134/5682/5705/5709/5753/5695/5711/5683/5699/5702/8900/5696/5691/7314/5718/5700/5707/898/890/9861/6502/5698/5692/5713/595/5710/5719/6233/1163/1019/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/5690/5717/1027/9491/6500/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721 59 Influenza_A_virus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 59/4622 60/10654 1.1196764814832132e-20 1.2522461768908255e-19 4.912433236654772e-20 8454/5689/5682/9039/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/5970/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 59 Influenza_A_virus R-HSA-2408557 Selenocysteine synthesis 83/4622 93/10654 1.6770378375739232e-20 1.8460621235656257e-19 7.241912253427385e-20 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/6208/6170/6203/6147/6222/6134/6155/6231/6142/23521/6207/6233/51091/6188/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/79048/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 83 Influenza_A_virus R-HSA-72764 Eukaryotic Translation Termination 83/4622 93/10654 1.6770378375739232e-20 1.8460621235656257e-19 7.241912253427385e-20 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/6208/6170/6203/6147/6222/2935/6134/6155/6231/6142/23521/6207/6233/6188/6122/6230/6194/2107/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 83 Influenza_A_virus R-HSA-1169408 ISG15 antiviral mechanism 68/4622 72/10654 1.861254099537876e-20 2.032838461839024e-19 7.974616660026591e-20 3839/23165/5335/348995/317649/57122/11274/23511/4734/23279/8672/23225/1973/3836/4599/9972/8021/7334/55746/7314/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/1977/51191/6233/5610/6396/129401/4928/3838/5903/55706/7175/4600/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/7318/1974/5595/3837/81929/9631/79023/23636/7316/53371/9688/5300/9775/5495/8480 68 Influenza_A_virus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 58/4622 59/10654 2.5564746290837163e-20 2.770505063146539e-19 1.0868407031845094e-19 8454/5689/5682/9039/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 58 Influenza_A_virus R-HSA-1234174 Cellular response to hypoxia 70/4622 75/10654 3.3267778711729905e-20 3.550256079312856e-19 1.3927290244123165e-19 5689/5682/64344/7321/3091/143471/5705/5709/9978/5695/5711/1387/5683/5699/7428/5702/2056/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/405/768/112399/84962/5706/5714/10370/5688/5687/5708/5704/7311/2034/55662/5694/5684/5720/7422/5690/5717/9491/10197/7316/10213/8994/7322/5715/5701/112398/5685/5686/2033/8453/5716/54583/5693/5721 70 Influenza_A_virus R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 70/4622 75/10654 3.3267778711729905e-20 3.550256079312856e-19 1.3927290244123165e-19 23165/8683/6431/84271/199746/348995/57122/23511/65109/23279/23225/9877/9972/8021/55746/7919/6432/8563/6430/80145/10762/22794/9785/11338/29107/4116/79902/9883/51213/10250/26097/51362/57187/6396/129401/79228/2733/84324/4928/5903/55706/7175/6428/10212/55110/84321/6429/4927/10569/9295/10482/8086/9939/6426/22916/10921/81929/9631/79023/23636/4686/53371/7307/9688/9984/10189/9775/84248/6427/8480 70 Influenza_A_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 84/4622 95/10654 4.006335944551852e-20 4.211171165777059e-19 1.651999230005156e-19 8454/3725/9252/4790/10333/4792/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/11213/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/6195/10454/6233/2353/5600/5608/4791/1846/351/387522/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/23291/114609/6288/6285/5609/1385/5599/7097/57161 84 Influenza_A_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 84/4622 95/10654 4.006335944551852e-20 4.211171165777059e-19 1.651999230005156e-19 8454/3725/9252/4790/10333/4792/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/11213/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/6195/10454/6233/2353/5600/5608/4791/1846/351/387522/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/23291/114609/6288/6285/5609/1385/5599/7097/57161 84 Influenza_A_virus R-HSA-5688426 Deubiquitination 206/4622 297/10654 4.5056439523516335e-20 4.70066436222954e-19 1.8440223874117842e-19 5689/221937/645836/5682/79594/7419/10474/7321/4738/7375/9817/10445/91833/3091/143471/100287513/5705/11274/55031/8239/5709/5695/4792/9986/11047/4609/392188/4194/4089/100287144/5711/7347/4088/5683/324/408/64135/5699/8312/100287327/5702/8900/8975/57599/377630/672/6881/51616/7187/7040/728386/7345/3054/1540/80351/100287404/5696/5691/23252/7314/5718/3607/90865/2648/5700/122706/5707/8027/8737/83444/8767/55611/100287364/51720/57646/23198/63967/9101/8517/86/993/890/7417/983/4092/2099/1643/9861/23586/81847/100287441/8850/7128/29844/7046/6502/5698/9146/5692/5713/5710/10454/8473/7157/10869/9958/5719/6233/100287478/9804/55593/84282/10318/23770/8607/7874/100287178/5886/100287238/10600/23326/8237/4303/409/330/5706/4287/27005/7706/580/7416/79155/25862/9738/8658/84132/5714/79589/27430/64127/5688/9097/5687/8078/5708/4087/63891/7189/5704/7048/7311/367/114548/387/60/29761/5694/7528/9960/23358/23032/5684/8295/5720/10617/7186/56957/6885/991/10392/5690/2625/57506/5717/9491/4086/1080/10197/64750/29086/7316/10213/55252/8678/9100/7415/5715/5701/4798/329/9099/5685/5686/2033/5728/5716/79184/78990/5887/9736/5693/154/10254/5721/100287205/4193 206 Influenza_A_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 72/4622 78/10654 5.271332494458891e-20 5.45875764981743e-19 2.1414146039868092e-19 3443/3442/4790/80143/7321/9140/79132/9474/4792/3093/1387/64135/83737/7187/1540/3551/7314/3445/8737/29110/4214/9636/841/8517/3444/7323/5970/23586/7128/3447/3451/3448/3661/3439/51191/6233/10010/55593/84282/8772/3452/4791/3446/3665/351/54476/7706/843/3440/9246/7189/7311/7318/79671/5094/9641/3456/1147/3441/7186/57506/3449/84166/7316/4793/3146/7322/2033/6288/54941/6285/5300 72 Influenza_A_virus R-HSA-72187 mRNA 3'-end processing 57/4622 58/10654 5.834648017919079e-20 5.997674947831524e-19 2.352826329207307e-19 8683/6431/84271/51585/199746/81608/1477/65109/9877/7919/53981/6432/8563/6430/11051/80145/8106/22794/9785/11338/4116/1478/51213/10250/26097/51362/23283/10914/57187/79228/84324/6428/10212/55110/84321/6429/10898/10569/9295/51692/9939/6426/22916/1479/10921/79869/29894/4686/8189/10978/7307/9984/10189/9775/84248/6427/55339 57 Influenza_A_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 139/4622 182/10654 6.800315880846654e-20 6.939300438995345e-19 2.7222163456942813e-19 1912/23165/7068/7486/9112/6045/9212/80012/10274/348995/6613/57122/23511/28996/4792/3190/9759/9612/8856/1911/6790/6672/23279/1387/23225/23512/165918/57332/7022/7067/7428/1107/5371/8924/672/115426/9972/10499/6612/5914/8021/6117/11315/55746/7421/4286/10062/7150/6670/83746/3622/1788/51564/51588/3619/7153/51602/8517/332/10762/5465/1655/5970/2099/79902/9656/9883/84733/3066/7157/7158/10155/9063/7155/7690/6396/129401/7703/4791/6015/8554/7020/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/5111/4927/10521/1616/2908/8243/142/1069/8086/7329/367/25942/9641/648/23468/5905/81929/5893/1487/55143/9631/5468/7021/8204/3090/79023/23636/10735/3183/4306/53371/6996/9688/7341/2033/9126/3065/6256/5987/6294/8648/8480/10891/7508/4193 139 Influenza_A_virus R-HSA-446652 Interleukin-1 family signaling 113/4622 140/10654 8.866664625756834e-20 8.982316773049315e-19 3.523670686513586e-19 8454/834/5689/5777/4790/5682/26469/8878/143471/5705/5709/9978/5695/4792/3606/5711/4088/5683/5699/5702/3654/51135/7334/3551/5696/5691/7314/3596/257397/5718/8945/1326/90865/11213/5700/122706/5707/8767/29110/23198/23118/8517/3565/5970/9861/5698/5692/5713/5710/10454/5719/6233/7850/5781/5608/4791/3557/351/5782/387522/54472/5706/79155/6774/5714/64127/3552/5688/5687/5708/3656/57162/7189/5704/7311/5694/6416/3554/3556/1147/5684/5720/6885/5604/4215/10392/5690/3553/5717/9491/6500/25930/246330/10197/4615/7316/10213/7335/4793/5775/3146/5715/5701/23291/5685/5686/6288/6285/5716/5599/57161/5693/5721 113 Influenza_A_virus R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 59/4622 61/10654 1.968928214218333e-19 1.9802601751634745e-18 7.768357437393045e-19 71/51517/4651/147179/10094/8976/2885/3071/5879/26999/25/1072/10093/10006/4771/5594/4644/4641/7456/10810/7410/7409/23191/10109/10787/2214/5747/2209/10451/1793/6850/10152/10092/4650/10163/55845/998/695/3326/10097/60/5058/63916/5595/3984/4690/4627/10458/919/10552/8936/917/3320/1398/10096/7454/9844/10095/2212 59 Influenza_A_virus R-HSA-1236974 ER-Phagosome pathway 75/4622 83/10654 2.1319452896603255e-19 2.1288996535322395e-18 8.351454856488945e-19 8773/5689/5682/3107/811/143471/5705/10333/5709/5695/567/3106/5711/5683/929/5699/5702/3133/3551/5696/5691/7314/5718/5700/122706/5707/23198/8517/7096/9861/5698/5692/5713/5710/5719/6233/3135/6890/5706/9554/29927/5714/5688/5687/5708/2923/695/5704/7311/5694/8673/3105/23643/1147/5684/5720/5690/5717/9491/10197/7099/4615/7316/10213/5715/5701/9341/5685/5686/114609/5716/3134/7097/5693/5721 75 Influenza_A_virus R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 140/4622 185/10654 2.164976441084744e-19 2.1465511096712566e-18 8.420699707391949e-19 6158/5393/6138/6227/6206/6234/6191/6128/6132/10557/6129/23404/6176/10528/84135/27340/27043/6224/6146/6154/6202/51096/6169/55272/6175/6218/5394/6173/11102/6167/28987/23481/51077/6156/117246/6143/6139/23160/26168/11340/3921/10799/6208/6170/10813/6203/23246/54913/6147/6222/1454/56902/51602/6134/6155/6231/6142/23521/10171/5822/6207/10969/10556/6233/6188/79707/1453/4691/23016/118460/6122/79897/6230/2091/6194/6166/8780/9277/6136/6125/6232/90459/6160/6193/10200/6210/6229/6205/140801/6235/55720/6181/55759/705/7311/6223/25873/51010/26354/56915/51202/9045/6187/6168/6157/6137/22894/84946/6144/9349/55813/4736/22803/51121/6159/25879/6217/81887/6152/51065/6141/55781/6164/6209/11224/6165/6130/6204/6228/51013/6124/83732/6189/6135/6201/6161/54512/10885/6133/9188 140 Influenza_A_virus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 77/4622 86/10654 2.6424478700814376e-19 2.601508536882993e-18 1.0205451003057295e-18 5295/5335/71/51517/5291/4651/2268/147179/10094/2534/8976/2885/3071/5879/26999/25/1072/5290/10093/10006/5336/4771/5594/4644/4641/6714/7456/10810/7525/7410/5580/7409/23191/3710/10109/10787/2214/5747/2209/10451/1793/6850/10152/10092/4650/10163/4067/55845/998/695/3326/10097/60/5058/63916/5595/3984/4690/4627/10458/3708/919/3055/10552/10768/8936/917/3320/1398/10096/7454/9844/5296/5581/5338/10095/2212 77 Influenza_A_virus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 55/4622 56/10654 3.03540674720523e-19 2.9674815612537843e-18 1.1641125618652373e-18 5689/5682/26986/143471/5705/5709/5695/5711/5683/5699/5702/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/9861/5698/5692/5713/1981/5710/5719/6233/3315/5706/5714/5688/5687/5708/5704/7311/5694/3304/5684/5720/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 55 Influenza_A_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 74/4622 82/10654 4.483232162175377e-19 4.352471224111929e-18 1.7074297927583127e-18 8454/5689/5682/5526/1452/143471/5705/5709/9978/5695/5711/5683/324/5699/8312/5702/5518/5696/5691/7314/5515/5718/8945/5700/122706/5707/23198/5528/9861/5519/2932/5698/5692/5713/5710/5719/6233/7090/5706/23401/5714/6934/5688/5687/5708/5529/7088/5704/7311/5694/5516/5684/5720/1487/1499/5525/139285/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/3065/5527/1488/5716/5693/5721 74 Influenza_A_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 76/4622 85/10654 5.50727139009052e-19 5.2375274852697595e-18 2.0546282808715796e-18 8454/3725/9252/4790/4792/1432/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/6195/10454/6233/2353/5600/5608/4791/1846/351/81793/387522/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/5595/5516/1147/6885/5604/10392/6500/246330/4615/7100/7316/7335/4205/4793/3146/23291/6288/6285/5609/1385/5599/57161 76 Influenza_A_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 76/4622 85/10654 5.50727139009052e-19 5.2375274852697595e-18 2.0546282808715796e-18 8454/3725/9252/4790/4792/1432/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/6195/10454/6233/2353/5600/5608/4791/1846/351/81793/387522/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/5595/5516/1147/6885/5604/10392/6500/246330/4615/7100/7316/7335/4205/4793/3146/23291/6288/6285/5609/1385/5599/57161 76 Influenza_A_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 76/4622 85/10654 5.50727139009052e-19 5.2375274852697595e-18 2.0546282808715796e-18 8454/3725/9252/4790/4792/1432/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/4214/23118/8517/5528/5970/9261/5519/5598/6195/10454/6233/2353/5600/5608/4791/1846/351/81793/387522/51295/79155/7867/64127/5602/3656/57162/7189/7311/6416/5595/5516/1147/6885/5604/10392/6500/246330/4615/7100/7316/7335/4205/4793/3146/23291/6288/6285/5609/1385/5599/57161 76 Influenza_A_virus R-HSA-2990846 SUMOylation 141/4622 188/10654 6.578707021691921e-19 6.214211092111693e-18 2.4377712363452996e-18 1912/10054/23165/7068/7486/9112/6045/9212/80012/10274/348995/6613/57122/23511/28996/4792/3190/9759/9612/8856/1911/6790/6672/23279/1387/23225/23512/165918/57332/7022/7067/7428/1107/5371/8924/672/115426/9972/10499/6612/5914/8021/6117/11315/55746/7421/4286/10062/7150/6670/83746/3622/1788/51564/51588/3619/7153/51602/8517/332/10762/5465/1655/5970/2099/79902/9656/9883/84733/3066/7157/7158/10155/9063/7155/7690/6396/129401/7703/4791/6015/8554/7020/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/5111/4927/10521/1616/2908/8243/142/1069/8086/7329/367/25942/9641/648/23468/5905/81929/5893/29843/1487/55143/9631/5468/7021/8204/3090/79023/23636/10735/3183/4306/53371/6996/9688/7341/2033/9126/3065/6256/5987/6294/8648/8480/10891/7508/4193 141 Influenza_A_virus R-HSA-5621481 C-type lectin receptors (CLRs) 113/4622 142/10654 7.246119885252955e-19 6.7987084560963966e-18 2.667063553667813e-18 8454/5689/4586/9252/4893/4790/5682/7321/9039/29108/143471/5705/5530/5709/5695/4792/5711/1387/5683/2534/5699/5702/5894/3845/7334/3265/3551/5062/5696/5691/7314/257397/5718/8945/4773/5700/122706/5707/5567/5336/4582/23198/23118/10892/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/3710/801/4791/5170/387522/4772/5706/56667/6850/8915/5714/5566/5688/5687/4067/5708/5063/7189/5704/7311/5971/5694/5058/997/1147/5684/5720/6885/84433/5690/3553/5717/9491/6500/3708/10197/7316/10213/94025/7335/10768/7322/5715/5701/23291/5685/5686/2033/5534/5716/5693/5721/2207/26253 113 Influenza_A_virus R-HSA-73856 RNA Polymerase II Transcription Termination 63/4622 67/10654 9.409764736005173e-19 8.769900733956821e-18 3.440342054356979e-18 8683/6431/84271/51585/199746/81608/1477/65109/9877/7919/53981/6432/8563/6430/134353/11051/80145/8106/22794/9785/11338/4116/1478/51213/10250/26097/51362/23283/6636/10914/57187/79228/84324/6635/6428/10212/6637/55110/84321/6429/10898/10569/9295/51692/9939/6426/22916/1479/10921/79869/29894/4686/8189/10978/7307/9984/10189/6634/9775/84248/6427/55339/6628 63 Influenza_A_virus R-HSA-9604323 Negative regulation of NOTCH4 signaling 53/4622 54/10654 1.5763885772451793e-18 1.459464391383285e-17 5.7253290257562804e-18 8454/5689/5682/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/5707/7534/9861/5698/5692/5713/5710/5719/6233/5706/10460/5714/5688/5687/5708/4855/5704/7311/5694/5684/5720/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721 53 Influenza_A_virus R-HSA-4420097 VEGFA-VEGFR2 Pathway 85/4622 99/10654 1.5977366331136488e-18 1.4616669948550004e-17 5.733969613127439e-18 5295/4893/857/5335/71/5579/5291/5578/1432/2534/9475/3690/5603/2475/6093/9564/3845/3265/3071/8877/5062/5829/5879/26999/5290/5567/10006/5921/1500/9261/6714/10810/10000/3728/7410/5580/7409/23191/3685/3791/3710/5600/6300/801/10787/253260/5170/5590/6461/5747/3315/10451/1793/10152/7867/64223/5566/1003/10163/55845/5063/998/208/79109/2185/387/60/5058/63916/558/1495/1499/4690/207/7422/10458/3708/9047/10768/8936/3320/4846/1398/9844/5296 85 Influenza_A_virus R-HSA-8878159 Transcriptional regulation by RUNX3 83/4622 96/10654 1.5996784707640564e-18 1.4616669948550004e-17 5.733969613127439e-18 5689/5682/5705/6097/6696/5709/5695/9759/10413/4609/4089/22938/5711/1387/7005/4088/5683/7003/5699/5702/9794/7040/3845/5696/5691/7314/5718/8463/2648/5700/5707/3280/463/6714/9861/8850/5698/5692/5713/595/5710/7157/5719/6233/1029/864/5706/5714/6934/5688/5687/5708/5704/7311/5694/4851/3676/57154/5684/5720/2309/1499/10018/5690/5717/9491/10197/64750/7316/10213/1026/5715/5701/5685/5686/2033/861/5716/25937/3516/5693/5721/4193 83 Influenza_A_virus R-HSA-8951664 Neddylation 167/4622 234/10654 1.946229585731325e-18 1.7667720525015538e-17 6.930865442009708e-18 8454/5689/56995/5682/64344/55884/7321/9021/4738/26235/9817/9039/154881/5929/3091/143471/5705/8452/5709/9978/5695/7704/10980/10489/5711/7347/5683/23113/5699/79269/10987/7428/5702/401036/140461/79176/6468/25793/51666/90293/54461/5696/5691/9820/7314/51514/5718/54165/8945/64410/23363/23038/5700/122706/5707/23198/140462/55827/51130/332/7323/9306/10517/50717/84861/27252/1643/26118/9861/23369/6502/90864/55832/5698/5692/5713/9903/26190/10238/5710/9040/5719/10116/6233/83987/8835/127247/54939/26268/115290/51725/140459/10537/8451/899/26224/9655/149951/142686/5931/144699/5706/200845/26263/8450/84078/5714/55527/26272/5688/55336/5687/26270/1161/5708/1642/5704/2873/7311/2034/8533/26232/51667/5694/150684/51138/9318/5684/79754/8065/5720/11091/25879/54850/5690/5717/9491/6500/28952/26259/10197/53339/7316/10213/222235/7322/5715/5701/23291/5685/5686/55294/8453/80176/8139/23142/126433/26267/5716/80204/8883/23014/8816/5693/5721/51676/50813 167 Influenza_A_virus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 62/4622 66/10654 2.056038168434467e-18 1.8544137803041193e-17 7.27467494570022e-18 5689/5682/64344/7321/3091/143471/5705/5709/9978/5695/5711/5683/5699/7428/5702/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/112399/84962/5706/5714/5688/5687/5708/5704/7311/2034/5694/5684/5720/5690/5717/9491/10197/7316/10213/8994/7322/5715/5701/112398/5685/5686/8453/5716/54583/5693/5721 62 Influenza_A_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 67/4622 73/10654 2.3774220818563508e-18 2.130535942586653e-17 8.357873850520639e-18 8454/5689/7291/5682/143471/5705/5709/9978/5695/5711/5683/2101/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/11059/2099/9861/2932/6502/5698/5692/5713/5710/5719/6233/133522/5706/5714/6772/5688/5687/2908/5708/5704/7311/860/1750/5694/57154/5684/5720/10273/5690/5717/9491/6500/59269/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721/10891 67 Influenza_A_virus R-HSA-194138 Signaling by VEGF 90/4622 107/10654 2.7089837450170748e-18 2.412203360212656e-17 9.462826222956056e-18 5295/4893/857/5335/71/5579/5291/5578/8829/1432/2534/9475/3690/5603/2475/6093/9564/3845/3265/3071/8877/5062/5829/5879/26999/5290/5567/10006/5921/1500/9261/6714/2321/10810/10000/3728/7410/5580/2324/7409/23191/3685/3791/3710/5600/6300/801/10787/253260/5170/5590/6461/5747/7424/3315/10451/1793/10152/7867/64223/5566/1003/10163/55845/5063/998/208/79109/2185/387/60/5058/63916/558/1495/1499/4690/207/7422/10458/3708/9047/10768/8936/3320/4846/1398/9844/5228/5296 90 Influenza_A_virus R-HSA-8868773 rRNA processing in the nucleus and cytosol 144/4622 195/10654 3.0910452797696028e-18 2.7349881652644963e-17 1.0729077886475436e-17 6158/5393/6138/6227/6206/6234/6191/6128/6132/10557/6129/23404/55226/6176/10528/84135/27340/27043/6224/6146/6154/6202/51096/6169/55272/6175/6218/5394/6173/11102/6167/28987/23481/51077/6156/117246/6143/6139/23160/26168/11340/3921/10799/6208/6170/10813/6203/23246/54913/6147/27292/6222/1454/56902/51602/6134/6155/6231/6142/23521/10171/5822/6207/10969/10556/6233/6188/79707/1453/4691/23016/118460/6122/79897/6230/2091/55651/6194/6166/8780/9277/6136/6125/6232/90459/6160/6193/10200/6210/6229/6205/140801/6235/55720/6181/55759/705/7311/6223/25873/51010/26354/56915/51202/9045/6187/6168/6157/6137/22894/84946/6144/9349/55813/4736/22803/51121/6159/25879/6217/81887/6152/51065/6141/55781/6164/6209/11224/6165/6130/6204/1736/6228/51013/6124/83732/6189/6135/6201/6161/54512/10885/6133/9188 144 Influenza_A_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 84/4622 98/10654 3.1961942896833024e-18 2.7926747606107855e-17 1.0955376479769742e-17 8454/3725/9252/4790/10333/4792/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/11213/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/6195/10454/6233/2353/5600/5608/4791/1846/351/387522/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/23291/114609/6288/6285/5609/1385/5599/7097/57161 84 Influenza_A_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 84/4622 98/10654 3.1961942896833024e-18 2.7926747606107855e-17 1.0955376479769742e-17 8454/3725/9252/4790/10333/4792/1432/929/3654/51135/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/11213/8767/1849/5594/4214/23118/8517/5528/5970/7096/9261/5519/5598/6195/10454/6233/2353/5600/5608/4791/1846/351/387522/51295/79155/8651/7867/64127/5602/3656/57162/695/7189/7311/6416/5595/5516/23643/1147/6885/5604/10392/6500/246330/7099/4615/7316/7335/4205/4793/3146/23291/114609/6288/6285/5609/1385/5599/7097/57161 84 Influenza_A_virus R-HSA-4641258 Degradation of DVL 55/4622 57/10654 4.9904074948050515e-18 4.3065368381095445e-17 1.6894102045441404e-17 5689/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/1855/5696/5691/7314/5718/5700/122706/5707/1856/23198/9861/5698/5692/5713/5710/5719/6233/1857/5706/5714/5688/5687/5708/51339/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/23072/5693/5721 55 Influenza_A_virus R-HSA-69541 Stabilization of p53 55/4622 57/10654 4.9904074948050515e-18 4.3065368381095445e-17 1.6894102045441404e-17 5689/5682/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/51230/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721/4193 55 Influenza_A_virus R-HSA-195258 RHO GTPase Effectors 218/4622 327/10654 6.024024227162842e-18 5.166617097897946e-17 2.026810863643423e-17 55839/11130/71/6249/51517/5579/9735/7531/5526/51807/10971/5578/9212/347688/7533/2810/147841/147179/348995/10381/57122/6280/1780/23122/3688/5048/57405/8655/10094/23279/1432/2017/2491/7846/23081/9475/1060/4628/11004/8976/1855/2885/23433/6093/9184/8826/10499/5518/23332/25909/3071/10726/81930/5062/55746/5879/5515/85415/26999/25/79682/1072/10403/79861/4638/25936/4659/10093/1856/10006/4771/389/5594/3619/64105/7534/332/5528/6714/79902/3796/5519/7456/81565/999/10810/5880/91687/11243/10376/11113/83540/5580/1857/9055/23191/7514/54820/29984/1729/5217/6396/5600/801/64946/9793/30849/10109/5586/140735/5500/10787/4221/3831/220134/5170/84617/4928/5590/5903/55055/5747/80776/1783/401541/2316/7532/10382/79172/7277/79980/6232/5501/10152/6279/54821/10092/9183/10163/1062/699/347733/22919/55845/5063/3895/5529/51143/998/695/10097/57120/367/10383/5347/387/60/84790/84643/5058/7280/7529/5595/1778/5516/5905/81929/3984/54908/55143/1495/1499/5525/4690/1058/991/79019/4627/348235/80152/10458/1063/3985/8379/1027/1080/23421/55920/79023/30851/6242/1781/10398/4085/5289/5585/5216/10552/100527963/81624/55166/8936/4637/51466/995/79003/391/23028/1742/5527/10096/7454/701/3799/103910/57551/5300/10095 218 Influenza_A_virus R-HSA-180534 Vpu mediated degradation of CD4 51/4622 52/10654 8.171726174942118e-18 6.800043567005406e-17 2.667587303975466e-17 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/920/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Influenza_A_virus R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 51/4622 52/10654 8.171726174942118e-18 6.800043567005406e-17 2.667587303975466e-17 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Influenza_A_virus R-HSA-69610 p53-Independent DNA Damage Response 51/4622 52/10654 8.171726174942118e-18 6.800043567005406e-17 2.667587303975466e-17 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Influenza_A_virus R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 51/4622 52/10654 8.171726174942118e-18 6.800043567005406e-17 2.667587303975466e-17 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Influenza_A_virus R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 51/4622 52/10654 8.171726174942118e-18 6.800043567005406e-17 2.667587303975466e-17 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/2932/5698/5692/5713/595/5710/5719/6233/1019/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Influenza_A_virus R-HSA-5610780 Degradation of GLI1 by the proteasome 57/4622 60/10654 1.1450029947140847e-17 9.471681577575682e-17 3.715643477085258e-17 8454/5689/5682/143471/5705/5709/9978/5695/5711/5683/5699/5702/83737/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/8650/9861/5698/5692/5713/5710/5719/6233/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/2735/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 57 Influenza_A_virus R-HSA-8878166 Transcriptional regulation by RUNX2 98/4622 121/10654 1.613423066026659e-17 1.3268032037089817e-16 5.204912801237705e-17 8454/8493/5689/7291/5682/5925/143471/5705/5709/9978/5695/9759/10413/4089/5711/5683/2101/5699/5702/5696/5691/7314/5718/25/5700/122706/5707/5594/3280/23198/10013/11059/983/6714/2099/9861/2932/6502/5698/10000/5692/5713/595/5710/5719/6233/7525/133522/4091/117581/1019/5706/891/5714/6772/5688/5687/4322/2908/5708/208/5704/7311/367/860/1750/5694/5595/57154/5684/8841/5720/23462/10273/207/5690/5717/9491/6500/4086/59269/10197/7316/10213/4094/1026/5715/5701/5685/5686/55294/861/5716/25937/581/5693/5721/10891 98 Influenza_A_virus R-HSA-1226099 Signaling by FGFR in disease 59/4622 63/10654 2.1309323386166534e-17 1.7421306487637903e-16 6.834199744039868e-17 5295/4893/11052/5335/9530/613/5431/6776/5435/5433/11064/5439/2264/2885/9846/2252/3845/3265/7750/8805/26127/5290/8823/8074/2260/5438/2249/2248/399687/2247/2246/2251/6777/1523/2963/5434/5436/9208/6774/2263/6772/2962/6654/11160/2549/5432/22916/5440/5430/8817/5441/2254/4686/26281/10818/2261/5437/2255/27006 59 Influenza_A_virus R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 53/4622 55/10654 2.5015604508563584e-17 2.0098744312052812e-16 7.884531124598686e-17 8454/5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/51343/7311/5694/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 53 Influenza_A_virus R-HSA-4641257 Degradation of AXIN 53/4622 55/10654 2.5015604508563584e-17 2.0098744312052812e-16 7.884531124598686e-17 5689/5682/143471/5705/5709/5695/5711/5683/5699/8312/5702/80351/5696/5691/7314/5718/5700/122706/5707/23198/9861/81847/5698/5692/5713/5710/5719/6233/5706/8658/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/5716/5693/5721 53 Influenza_A_virus R-HSA-8941858 Regulation of RUNX3 expression and activity 53/4622 55/10654 2.5015604508563584e-17 2.0098744312052812e-16 7.884531124598686e-17 5689/5682/5705/5709/5695/5711/5683/5699/5702/7040/5696/5691/7314/5718/5700/5707/6714/9861/5698/5692/5713/5710/5719/6233/1029/864/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/2033/5716/5693/5721/4193 53 Influenza_A_virus R-HSA-4086400 PCP/CE pathway 79/4622 92/10654 2.604269242305475e-17 2.0686184095130988e-16 8.114977722734165e-17 5689/5579/5682/5578/1212/5582/143471/5705/5709/5695/5881/5711/5683/5699/5702/57216/1855/163/5696/5691/4920/7314/5879/5718/161/5700/122706/5707/1856/8322/23198/9861/5698/5880/5692/5713/5710/5719/6233/7474/1857/1213/1211/7855/1175/7976/1173/409/5706/160/5714/5688/5687/5708/5704/7311/387/5694/57154/5684/5720/5690/5717/9491/10197/64750/7316/10213/54361/5216/5715/5701/5685/5686/23513/5716/5693/5721/6259 79 Influenza_A_virus R-HSA-877300 Interferon gamma signaling 79/4622 92/10654 2.604269242305475e-17 2.0686184095130988e-16 8.114977722734165e-17 80263/5777/960/5770/3107/817/9021/3383/3662/3115/4684/567/6672/3113/3106/3459/3717/3117/11074/5371/3133/3127/4938/4261/818/115362/7412/85363/9830/163351/3126/2634/115361/10437/3458/3661/5580/81603/10107/4940/5781/3660/8554/3135/3665/3120/10379/2633/3123/23650/2209/8638/7706/3122/3394/3663/6772/8651/3659/2635/816/3716/3125/7726/3105/3460/815/6737/23321/4281/3119/4502/51127/3664/4939/388646/7341/3134/5724 79 Influenza_A_virus R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 49/4622 50/10654 4.227891272214325e-17 3.3393175133082636e-16 1.3099799897851106e-16 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 49 Influenza_A_virus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 52/4622 54/10654 5.594306010284151e-17 4.3937302260546314e-16 1.7236152757883163e-16 8454/5689/5682/143471/5705/5709/9978/5695/6790/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 52 Influenza_A_virus R-HSA-5689880 Ub-specific processing proteases 156/4622 220/10654 6.957814332295745e-17 5.434091863994107e-16 2.1317384693478877e-16 5689/645836/5682/79594/7419/10474/7375/9817/91833/3091/143471/100287513/5705/11274/55031/8239/5709/5695/4792/9986/11047/4609/392188/4194/4089/100287144/5711/4088/5683/408/64135/5699/8312/100287327/5702/8900/8975/57599/377630/6881/51616/728386/1540/80351/100287404/5696/5691/7314/5718/90865/2648/5700/122706/5707/8737/55611/100287364/57646/23198/63967/9101/8517/993/890/7417/4092/1643/9861/23586/81847/100287441/7046/6502/5698/9146/5692/5713/5710/10454/7157/10869/9958/5719/6233/100287478/9804/23770/8607/7874/100287178/100287238/10600/23326/8237/4303/409/330/5706/27005/7416/25862/9738/8658/84132/5714/79589/27430/5688/9097/5687/8078/5708/4087/63891/7189/5704/7311/367/29761/5694/9960/23358/23032/5684/8295/5720/7186/6885/991/5690/2625/5717/9491/4086/1080/10197/64750/7316/10213/8678/9100/5715/5701/329/9099/5685/5686/5728/5716/9736/5693/154/10254/5721/100287205/4193 156 Influenza_A_virus R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 67/4622 75/10654 7.825281263347461e-17 6.077635114533195e-16 2.384193881990659e-16 5295/5291/3082/941/2064/145957/2534/9965/2264/9542/2885/8660/2252/5879/1839/5290/3667/8823/2065/3815/2069/8074/2260/2249/6714/2099/2248/2247/5880/7409/2246/2251/5154/3932/118788/5781/940/930/2263/4233/8503/5159/29851/3084/10718/5293/1956/2549/685/8817/2100/2254/152831/1950/50852/26281/10818/2261/2255/391/2066/27006/942/5155/4254/5296/5156 67 Influenza_A_virus R-HSA-169911 Regulation of Apoptosis 51/4622 53/10654 1.250065340309314e-16 9.655200805261996e-16 3.787636186688879e-16 5689/5682/4976/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/115209/5715/5701/5685/5686/5716/5693/5721 51 Influenza_A_virus R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 91/4622 112/10654 1.572838150296985e-16 1.2016839168572094e-15 4.714082679637122e-16 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6728/6173/6167/6156/6143/6139/6745/3921/6208/6170/6203/6147/6222/6134/6747/6731/6155/6729/6231/6142/23521/6207/6233/6188/6122/6230/6194/6166/1650/6136/6125/6232/6160/6748/29927/60559/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/6730/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 91 Influenza_A_virus R-HSA-450294 MAP kinase activation 59/4622 64/10654 1.573019719491197e-16 1.2016839168572094e-15 4.714082679637122e-16 8454/3725/9252/4790/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/23118/8517/5528/9261/5519/5598/6195/10454/6233/2353/5600/5608/1846/387522/79155/7867/64127/5602/3656/7189/7311/6416/5595/5516/1147/6885/5604/10392/6500/7316/7335/4205/23291/5609/1385/5599 59 Influenza_A_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 47/4622 48/10654 2.1829471694685703e-16 1.6428094619430286e-15 6.444572921258323e-16 5295/5777/1437/5291/6776/3558/3717/2534/3563/2885/9846/1399/7314/3635/5290/1439/7534/3718/3567/6233/7525/7409/6777/5781/3562/6464/1438/6850/5566/8503/2889/4067/29760/3636/6654/3716/7311/5293/3561/3568/7316/3560/3055/867/1398/5296/3559 47 Influenza_A_virus R-HSA-5610783 Degradation of GLI2 by the proteasome 56/4622 60/10654 2.1857121596666902e-16 1.6428094619430286e-15 6.444572921258323e-16 8454/5689/5682/1452/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/9861/2932/5698/5692/5713/5710/5719/6233/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 56 Influenza_A_virus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 56/4622 60/10654 2.1857121596666902e-16 1.6428094619430286e-15 6.444572921258323e-16 8454/5689/5682/1452/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/9861/2932/5698/5692/5713/5710/5719/6233/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 56 Influenza_A_virus R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/4622 52/10654 2.790996861244583e-16 2.0865313433261643e-15 8.185248323717579e-16 5689/5682/143471/472/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Influenza_A_virus R-HSA-72312 rRNA processing 146/4622 205/10654 3.7767614134102065e-16 2.8084640723124834e-15 1.1017316329152954e-15 6158/5393/6138/6227/6206/6234/6191/6128/6132/10557/6129/23404/55226/6176/10528/84135/27340/27043/6224/6146/6154/6202/51096/6169/55272/6175/6218/5394/6173/11102/6167/28987/23481/51077/6156/117246/6143/6139/23160/26168/11340/3921/10799/6208/6170/10813/6203/23246/54913/6147/27292/6222/1454/56902/51602/6134/6155/6231/6142/23521/10171/5822/6207/10969/10556/6233/6188/79707/1453/4691/23016/118460/6122/79897/6230/2091/55651/6194/6166/3028/8780/9277/6136/6125/6232/90459/6160/6193/10200/6210/6229/6205/140801/6235/55720/6181/55759/705/7311/6223/25873/51010/26354/56915/51202/9045/6187/6168/6157/6137/22894/84946/6144/9349/55813/4736/22803/51121/6159/25879/6217/81887/6152/51065/6141/55781/6164/54931/6209/11224/6165/6130/6204/1736/6228/51013/6124/83732/6189/6135/6201/6161/54512/10885/6133/9188 146 Influenza_A_virus R-HSA-69002 DNA Replication Pre-Initiation 73/4622 85/10654 4.2421751992336504e-16 3.1226789347816156e-15 1.2249948987434843e-15 5689/5682/143471/5705/5709/5422/1869/4174/5695/84515/5711/10926/5683/5699/5702/55388/6117/5001/5696/5691/7314/5718/6118/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/23649/4172/8318/54107/4173/5706/5714/51053/6119/5688/5687/5427/5708/81620/5704/7311/5694/4176/56655/1017/5684/5720/8317/5690/5717/9491/10197/7316/10213/5426/4171/1871/5715/5701/5685/5686/5716/5693/5721 73 Influenza_A_virus R-HSA-9013694 Signaling by NOTCH4 71/4622 82/10654 4.243984246126659e-16 3.1226789347816156e-15 1.2249948987434843e-15 8454/5689/5682/23385/5705/5709/9978/5695/22938/5711/1387/4088/5683/5699/4853/5702/9794/5696/5691/7314/5718/2648/5700/5707/3280/7534/102/5664/9861/8850/5698/5692/5713/5710/5719/6233/2324/5663/5706/10460/5714/5688/5687/5708/59/4855/5704/7311/5694/4851/5684/5720/23462/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/2033/55294/5716/3516/5693/5721 71 Influenza_A_virus R-HSA-380108 Chemokine receptors bind chemokines 55/4622 59/10654 4.737258927137642e-16 3.4673759058316352e-15 1.3602159829367384e-15 729230/7852/1237/3576/6360/2920/2921/1236/6370/58191/1524/643/2833/6347/6387/10663/3579/6375/6846/6367/2826/6376/6354/3627/6346/9034/51554/2829/1233/6366/6373/6357/6361/10803/6351/3577/10563/10850/5473/4283/6356/56477/1234/57007/1238/6374/1230/2919/5196/6352/6348/6364/6372/6363/1232 55 Influenza_A_virus R-HSA-162599 Late Phase of HIV Life Cycle 107/4622 139/10654 4.891816824212835e-16 3.5618541251299705e-15 1.3972788187581619e-15 6884/23165/6875/27243/6874/348995/57122/5431/23511/5435/5433/51271/23279/23327/8732/23225/2965/27183/5439/6873/9972/6881/51616/8021/11198/51497/55746/92421/7314/137492/25978/51160/2959/91782/5438/10762/79720/4836/9397/79902/9883/83860/51510/2068/5902/5478/6233/7514/1025/6396/129401/6883/6829/25920/4928/2963/5434/5903/55706/7175/5436/6878/4331/4927/8148/2962/54457/8812/128866/905/2071/5901/8086/7311/93343/6880/6908/7251/1104/6882/2961/5432/22916/6877/5905/81929/5440/902/9631/5430/6749/79023/5441/23636/4686/7316/6872/53371/9688/6879/9150/5437/2968/138474/1022/8178/8480 107 Influenza_A_virus R-HSA-166520 Signaling by NTRKs 83/4622 101/10654 9.368031462093145e-16 6.785755432127573e-15 2.6619822152988977e-15 5295/627/9252/4893/5335/5291/1785/5605/5898/1432/2534/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5879/5515/5607/161/5290/3667/5899/1849/5594/5528/9261/6714/5519/5598/4909/4914/6195/1213/1211/5600/1175/6300/5781/1846/25920/4908/1173/6464/2904/7074/160/673/6774/26052/7867/5802/2889/6654/5900/387/2549/1020/4916/7529/5595/5516/4915/5604/10817/4205/57498/10818/4803/1398/1385/5906/8851/5296/581 83 Influenza_A_virus R-HSA-180585 Vif-mediated degradation of APOBEC3G 51/4622 54/10654 1.2990855908084574e-15 9.361451834794966e-15 3.6724014802561384e-15 5689/5682/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/60489/5706/5714/5688/5687/5708/5704/7311/5694/5684/8065/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Influenza_A_virus R-HSA-68949 Orc1 removal from chromatin 63/4622 71/10654 1.4426521747092392e-15 1.0342706360223161e-14 4.0573375601809105e-15 8454/5689/5682/143471/5705/5709/9978/4174/5695/84515/5711/5683/5699/5702/8900/5001/5696/5691/7314/5718/5700/122706/5707/23198/890/9861/6502/5698/5692/5713/5710/5719/6233/4172/4173/5706/5714/5688/5687/5708/81620/5704/7311/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 63 Influenza_A_virus R-HSA-162587 HIV Life Cycle 114/4622 152/10654 1.5541890672234345e-15 1.1085491408052865e-14 4.348724511403918e-15 6884/23165/6875/7852/27243/6874/348995/57122/5431/23511/5435/5433/51271/23279/23327/8732/23225/2965/27183/5439/6873/3836/9972/6881/51616/8021/11198/51497/55746/92421/7314/137492/25978/51160/2959/91782/5438/10762/79720/4836/9397/79902/9883/83860/51510/2068/5902/5478/6233/7514/1025/6396/129401/6883/6829/25920/4928/2963/5434/5903/55706/7175/5436/6878/920/4331/4927/8148/2962/54457/8812/128866/905/2071/5901/8086/7311/93343/6880/6908/7251/1104/2547/6882/2961/5432/22916/1234/6877/5905/81929/5440/902/9631/3159/5430/7520/6749/79023/5441/23636/4686/7316/6872/53371/9688/6879/9150/5437/2968/138474/1022/8178/8480 114 Influenza_A_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 87/4622 108/10654 1.9995214628397497e-15 1.41894974875633e-14 5.56639424065995e-15 5295/3605/7124/2308/1052/7291/356/3593/9021/6624/3082/5743/3091/3383/6097/6657/3576/3662/3688/4985/7133/3606/4609/4988/3717/6347/7040/3312/3569/4692/3596/3598/3592/7412/3911/4582/6367/4312/6778/332/4313/3565/5443/3718/149233/598/2247/2335/595/7157/2353/604/7076/51561/7297/9655/3566/7184/4318/58480/301/6774/6772/8651/1901/3552/79923/3716/6356/3586/596/2309/3561/207/5292/5451/7422/3553/2625/4314/1026/3320/4843/6288/7431/3162/4170 87 Influenza_A_virus R-HSA-111885 Opioid Signalling 76/4622 91/10654 2.6798460293315803e-15 1.8921337116189643e-14 7.422646365134255e-15 2788/5331/2770/817/5578/5582/5530/107/4988/2774/2782/5499/5518/814/2773/5515/2787/818/84152/5567/5594/10681/5142/112/5573/5528/111/5443/2792/5519/2785/2783/2784/5613/2771/5332/5580/3710/196883/115/801/2791/3838/113/10645/5566/84254/23236/816/2786/5577/1020/5141/109/5516/815/5321/54331/5575/59345/51764/94235/114/3708/5330/108/5173/55970/10768/346562/2793/5576/5534/1385/5144/2790 76 Influenza_A_virus R-HSA-194315 Signaling by Rho GTPases 279/4622 455/10654 3.004321016276552e-15 2.1105732566606132e-14 8.279562282359606e-15 55839/9639/11130/7984/71/6249/51517/5579/57522/392/9735/7531/5526/29/51807/10971/5578/9212/347688/613/1894/7533/2810/147841/147179/348995/116985/54509/10381/57122/10276/6280/1780/23122/3688/5048/57405/8655/10094/23279/5881/1432/2017/2491/9138/7846/23365/23081/9475/1060/9322/4628/51291/11004/8976/1855/2885/23433/6093/9184/8826/10499/5518/8874/23332/25909/3071/10726/81930/5062/55746/9411/2665/5879/10395/5515/85415/26999/25/79682/1072/10403/79861/4638/25936/4659/10093/1856/10006/4771/389/5594/3619/64105/7534/332/5528/6453/9828/6714/55114/79902/3796/5519/7456/81565/999/396/10810/5880/85360/91687/11243/10376/57584/11113/58504/83540/7410/5580/7409/1857/9055/23191/7514/54820/29984/1729/5217/6396/5600/91614/801/64946/9793/30849/10109/5586/140735/9886/5500/80728/10787/4221/3831/220134/5170/84617/4928/9743/5590/5903/55055/5747/80776/1783/401541/7204/64411/2316/7532/3633/10382/7074/79172/7277/10451/79980/58480/6232/5501/50650/10152/6279/393/54821/10092/9183/4650/10163/1062/699/94134/347733/22919/55845/5063/3895/5529/51143/998/695/6654/10097/57120/367/10383/5347/387/60/84790/84643/5058/7280/7529/5595/1778/5516/5905/81929/3984/54908/55143/1495/1499/5525/4690/1058/991/79019/57580/4627/10928/348235/80152/10458/1063/3985/8379/1027/11214/1080/23421/55920/79023/30851/6242/1781/9824/10398/4085/5289/5585/5216/4168/10552/100527963/81624/23263/55166/50649/9826/8936/4637/1123/51466/995/79003/391/23221/23028/89941/2/1742/90627/5527/10096/7454/701/3799/103910/57551/5296/5300/10095/201176/4952/4983/10672 279 Influenza_A_virus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 47/4622 49/10654 3.0900015111203113e-15 2.1599110562730976e-14 8.473109406808854e-15 9134/57060/2810/1869/6790/25904/1647/8900/55571/55835/57472/144455/85456/29883/1263/7027/7832/898/5934/890/10769/983/7157/5325/79733/1820/4869/4850/891/5111/246175/4848/23019/1874/1017/25946/4849/1027/9337/1026/5933/28984/2033/995/10498/581/3276 47 Influenza_A_virus R-HSA-5654738 Signaling by FGFR2 64/4622 73/10654 3.2643881610784085e-15 2.2704550493470723e-14 8.906762146749676e-15 5295/4893/5335/5431/5435/5433/8569/5439/7072/2885/7073/5518/2252/3845/3265/7314/5515/5290/8823/5594/8074/5438/3185/2249/6714/2248/4670/2247/6233/2246/2251/5781/5725/2963/5434/6464/5436/673/2263/2962/6654/7311/2549/5432/22916/5595/5516/5440/23543/5430/3178/8817/10817/5441/2254/4686/7316/26281/10818/867/5437/2255/27006/3187 64 Influenza_A_virus R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 52/4622 56/10654 4.7848693923693075e-15 3.311508619075392e-14 1.2990708459741582e-14 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/6469/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 52 Influenza_A_virus R-HSA-5696398 Nucleotide Excision Repair 88/4622 111/10654 8.502251009384776e-15 5.855244783802915e-14 2.2969524375885235e-14 2074/10445/5982/6613/7507/5431/5435/9978/5433/85015/10980/2965/5439/10987/2067/6612/6117/7334/10714/91603/7314/6118/83444/86/5438/1643/29844/5985/2068/5984/6233/8607/7874/5424/5886/8451/8554/10450/5434/5436/7515/54107/8450/4331/5425/5111/6119/5427/1161/1642/142/2071/1069/7329/51426/2873/7311/60/8533/5983/5432/51138/7528/56655/9318/5440/902/27339/5430/57804/5441/7336/54778/7316/5426/7341/4798/5437/2033/2968/56949/5887/9716/5981/1022/8178/50813/7508 88 Influenza_A_virus R-HSA-69481 G2/M Checkpoints 122/4622 168/10654 9.943581997982903e-15 6.814278251558871e-14 2.6731714246383346e-14 5689/83990/5682/9156/1763/7531/7486/10971/5982/7533/2810/11200/143471/472/5705/5709/4174/5695/84515/5711/4683/10926/5683/165918/84126/5699/5702/8924/55388/672/6117/7334/5001/7465/5696/83695/5691/7314/5718/6118/5700/122706/5707/51588/51720/23198/63967/7534/993/116028/983/9861/9656/5698/5692/5985/5713/5710/7157/5984/5719/6233/7158/5884/5810/4172/80010/8318/51512/7532/4173/5706/9133/580/11073/891/641/5714/6119/3364/10524/5688/5687/144715/5708/1111/5704/7311/5983/5694/4176/7529/1017/5684/5720/5883/10111/8317/5690/5717/9491/545/10197/7336/29086/7316/10213/4171/5715/9088/7341/5701/5685/5686/995/5716/5932/9025/79184/7156/5693/5721 122 Influenza_A_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 51/4622 55/10654 1.031418517096952e-14 6.999626635444363e-14 2.7458816934466632e-14 834/4790/7295/29108/1432/10628/5603/83737/3654/7334/1540/3551/7314/257397/8767/23118/841/8517/5970/5027/7128/837/598/10454/6233/5600/6300/5608/4791/351/387522/330/64127/3656/7189/3326/4210/7311/114548/1147/9447/596/6885/842/10392/10910/58484/7316/7335/22861/329 51 Influenza_A_virus R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 51/4622 55/10654 1.031418517096952e-14 6.999626635444363e-14 2.7458816934466632e-14 51807/347688/10381/1780/3305/8655/84516/832/7846/3306/3312/51164/3303/79861/3337/10376/3301/10540/140735/84617/5241/11258/1783/10382/93661/10294/55860/830/7277/10671/1639/2908/347733/51143/3326/367/10383/84790/3304/7280/10728/829/1778/4306/1781/2289/10121/3320/10963/55466/2288 51 Influenza_A_virus R-HSA-5610787 Hedgehog 'off' state 89/4622 113/10654 1.2443108488784825e-14 8.40360660257062e-14 3.296648625810778e-14 8454/5689/5682/1452/143471/10381/5705/5709/9978/5695/107/5711/7846/5683/5699/5702/83737/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/112/5573/5727/8650/111/9861/2932/5698/5692/5713/10376/5710/5719/6233/23322/196883/115/84617/54903/10382/7277/5706/113/5714/5566/5688/5687/347733/5708/5577/5704/7311/10383/84790/5694/7280/109/5684/5720/2735/5575/6608/5690/5717/9491/6500/114/10197/108/7316/10213/2778/5715/5701/5576/5685/5686/5716/23432/8481/5693/5721 89 Influenza_A_virus R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 48/4622 51/10654 1.3628615719920017e-14 9.160002296369319e-14 3.5933748937643365e-14 5689/5682/143471/5705/5709/5695/5711/4946/5683/5699/5702/5696/5691/5718/1728/51582/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/5706/4947/5714/5688/5687/5708/5704/5694/5684/5720/5690/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 48 Influenza_A_virus R-HSA-420499 Class C/3 (Metabotropic glutamate/pheromone receptors) 38/4622 38/10654 1.5153428408475533e-14 1.013612101198507e-13 3.97629624820738e-14 50833/5726/2550/50832/259294/2912/259295/9568/2911/2914/259296/259289/50835/338398/2916/259293/54429/222545/80835/50840/2913/2918/50838/83756/259286/259287/50836/846/259290/80834/259292/50834/259285/2917/50831/50839/50837/2915 38 Influenza_A_virus R-HSA-4608870 Asymmetric localization of PCP proteins 57/4622 64/10654 2.3024518783238192e-14 1.5327751075698568e-13 6.012919441637644e-14 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/57216/5696/5691/7314/5718/5700/122706/5707/1856/8322/23198/9861/5698/5692/5713/5710/5719/6233/7474/7855/7976/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/23513/5716/5693/5721 57 Influenza_A_virus R-HSA-388841 Costimulation by the CD28 family 61/4622 70/10654 2.748844607557481e-14 1.8212723987513546e-13 7.144664707096271e-14 5295/5777/5526/941/3115/3113/3117/2534/2885/2475/5518/3127/5062/5879/5515/1326/5290/5133/3126/5528/9020/6714/5519/29126/10000/1445/916/7525/7409/3932/5781/1493/940/253260/3120/5170/3123/3122/920/64223/8503/4067/29851/5063/5529/998/208/79109/3125/5058/5516/9402/5525/3119/207/919/915/917/942/5527/5296 61 Influenza_A_virus R-HSA-187037 Signaling by NTRK1 (TRKA) 67/4622 80/10654 9.302972189896468e-14 6.134695812016633e-13 2.4065782080119467e-13 5295/9252/4893/5335/5291/1785/5605/5898/1432/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5515/5607/161/5290/3667/5899/1849/5594/5528/9261/6714/5519/5598/4914/6195/1213/1211/5600/1175/6300/1846/1173/6464/160/673/6774/26052/7867/2889/6654/5900/387/7529/5595/5516/4915/5604/4205/57498/10818/4803/1398/1385/5906/5296 67 Influenza_A_virus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 65/4622 77/10654 1.018504770759222e-13 6.653596586548562e-13 2.6101376564955957e-13 1912/23165/7486/6045/80012/10274/348995/6613/57122/23511/1911/6672/23279/23225/165918/57332/5371/8924/672/9972/6612/8021/6117/55746/51564/51588/10762/79902/9656/9883/84733/9063/6396/129401/7703/6015/8554/4928/5903/55706/7175/1029/8535/5885/641/4927/8243/142/1069/8086/7329/648/81929/5893/9631/79023/23636/10735/53371/6996/9688/7341/9126/8480/7508 65 Influenza_A_virus R-HSA-9009391 Extra-nuclear estrogen signaling 65/4622 77/10654 1.018504770759222e-13 6.653596586548562e-13 2.6101376564955957e-13 5295/2788/4893/857/2770/2782/3845/3265/8877/2773/2787/1839/5290/5594/2069/10681/4313/2792/6714/2099/10000/2785/595/2783/2784/2771/7514/2353/801/2791/5170/5590/6464/5747/1903/3315/4318/8503/2786/208/1956/858/3480/5595/596/685/54331/2309/59345/207/1027/51764/94235/2100/1950/55970/4314/346562/2793/3320/4846/1385/5296/3276/2790 65 Influenza_A_virus R-HSA-5658442 Regulation of RAS by GAPs 59/4622 68/10654 1.1257784007253865e-13 7.286287982472641e-13 2.8583359979431113e-13 5689/4893/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/3845/3265/4763/5696/5691/7314/5718/5700/122706/5707/23198/5921/9861/5698/5692/5713/5710/5719/6233/9462/5706/84078/5714/5688/5687/5708/5704/7311/5694/5684/5720/153090/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721/161742 59 Influenza_A_virus R-HSA-68867 Assembly of the pre-replicative complex 59/4622 68/10654 1.1257784007253865e-13 7.286287982472641e-13 2.8583359979431113e-13 5689/5682/143471/5705/5709/1869/4174/5695/84515/5711/5683/5699/5702/5001/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/4172/4173/5706/5714/51053/5688/5687/5708/81620/5704/7311/5694/4176/5684/5720/5690/5717/9491/10197/7316/10213/4171/1871/5715/5701/5685/5686/5716/5693/5721 59 Influenza_A_virus R-HSA-5678895 Defective CFTR causes cystic fibrosis 54/4622 61/10654 2.0280550294094416e-13 1.3065534244766817e-12 5.125474995499971e-13 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/5696/5691/7314/5718/5700/122706/5707/79139/23198/9861/5698/5692/5713/5710/5719/10613/6233/5706/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 54 Influenza_A_virus R-HSA-190236 Signaling by FGFR 71/4622 87/10654 2.2826613340920573e-13 1.4638351124131634e-12 5.742474915798947e-13 5295/4893/5335/5431/5435/5433/8569/9965/5439/2264/7072/2885/7073/5518/2252/3845/3265/23769/7314/5515/5290/8823/5594/8074/2260/5438/3185/2249/6714/2248/4670/2247/6233/2246/2251/5781/5725/2963/5434/6464/5436/673/2263/2962/6654/7311/2549/5432/22916/5595/5516/5440/23543/5430/3178/8817/10817/5441/2254/4686/7316/152831/26281/10818/2261/867/5437/2255/27006/3187/161742 71 Influenza_A_virus R-HSA-163685 Integration of energy metabolism 84/4622 108/10654 2.5341933181810563e-13 1.6177179264005098e-12 6.34614140241447e-13 2788/5563/5331/2740/2770/5578/2769/107/2782/3630/2776/8826/5518/31/2181/6513/5515/2787/5567/1131/51422/10681/112/5573/5528/111/2792/5519/10554/51085/2785/2783/2784/2771/9370/7086/6844/2182/3710/196883/115/2791/2642/150/113/5566/775/2864/23236/6794/2641/6514/2786/5577/6888/773/5565/109/5516/54331/5575/59345/776/51764/94235/114/3708/4082/5330/3790/108/55970/2778/2194/2767/10768/152/2793/5576/47/5906/51094/9630/2790 84 Influenza_A_virus R-HSA-8848021 Signaling by PTK6 49/4622 54/10654 2.9771331017642153e-13 1.8832724326997163e-12 7.387884477347732e-13 4893/1796/5770/9021/27043/3091/116985/2064/5753/145957/9542/9564/3845/3265/5829/7314/5879/120892/1839/2065/2069/898/5921/6421/595/6233/1019/10657/1793/6774/2908/3084/10718/7311/2034/387/1956/63916/1017/685/207/55620/1027/7316/1950/867/2066/1398/9844 49 Influenza_A_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 49/4622 54/10654 2.9771331017642153e-13 1.8832724326997163e-12 7.387884477347732e-13 4893/1796/5770/9021/27043/3091/116985/2064/5753/145957/9542/9564/3845/3265/5829/7314/5879/120892/1839/2065/2069/898/5921/6421/595/6233/1019/10657/1793/6774/2908/3084/10718/7311/2034/387/1956/63916/1017/685/207/55620/1027/7316/1950/867/2066/1398/9844 49 Influenza_A_virus R-HSA-168325 Viral Messenger RNA Synthesis 41/4622 43/10654 3.688095890076621e-13 2.3225036280752777e-12 9.11094337946856e-13 23165/348995/57122/5431/23511/5435/5433/23279/23225/5439/9972/8021/55746/5438/10762/79902/9883/6396/129401/4928/2963/5434/5903/55706/7175/5436/4927/2962/8086/5432/81929/5440/9631/5430/79023/5441/23636/53371/9688/5437/8480 41 Influenza_A_virus R-HSA-1227986 Signaling by ERBB2 46/4622 50/10654 4.689887450307808e-13 2.9401177827490204e-12 1.153378032386296e-12 5295/4893/5335/26469/5578/2064/5753/145957/2534/4145/9542/2885/3845/3265/7314/1839/5290/2065/2069/9101/6714/10000/6233/7525/5580/1729/6464/5782/3084/208/6654/10718/7311/387/1956/2549/11140/8065/685/10273/207/7316/1950/3320/2066/5581 46 Influenza_A_virus R-HSA-1236975 Antigen processing-Cross presentation 78/4622 99/10654 5.316277117572384e-13 3.3179265224849075e-12 1.3015885236161711e-12 8773/5689/5682/3107/811/143471/5705/10333/5709/5695/567/3693/3106/5711/5683/929/5699/5702/3133/3551/5696/5691/7314/5718/5700/122706/5707/23198/8517/7096/9861/5698/5692/5713/5710/5719/6233/3685/3135/6890/2209/5706/9554/29927/5714/5688/5687/5708/2923/695/5704/7311/5694/8673/3105/23643/1147/5684/5720/5690/5717/9491/10197/7099/4615/7316/10213/5715/5701/9341/5685/5686/114609/5716/3134/7097/5693/5721 78 Influenza_A_virus R-HSA-5387390 Hh mutants abrogate ligand secretion 52/4622 59/10654 8.558543747238857e-13 5.270856457550627e-12 2.067702894649406e-12 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/6469/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 52 Influenza_A_virus R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 52/4622 59/10654 8.558543747238857e-13 5.270856457550627e-12 2.067702894649406e-12 5689/5682/143471/5705/5709/5695/84515/5711/5683/5699/5702/5001/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/51053/5688/5687/5708/81620/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 52 Influenza_A_virus R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 52/4622 59/10654 8.558543747238857e-13 5.270856457550627e-12 2.067702894649406e-12 6227/6206/1965/6234/6191/8668/6224/8662/26986/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/8663/8894/1981/6207/1977/6233/51386/6188/1978/1968/6230/6194/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/6209/6204/6228/3646/6189/6201 52 Influenza_A_virus R-HSA-76002 Platelet activation, signaling and aggregation 170/4622 262/10654 1.0827968328118396e-12 6.63925426434628e-12 2.6045113106877585e-12 5295/2788/2149/5777/5579/5770/5291/64805/2770/5175/3959/5578/5582/5908/3082/5583/2769/5028/1432/3920/374354/3309/2534/3690/408/2768/2782/87/2776/5894/10487/2885/51206/7040/9564/350/7043/2773/5879/5054/2787/1072/5290/7018/5336/813/7094/5594/10681/7414/7534/2792/6714/3671/22927/1191/9749/146850/27154/226/5588/5880/2335/5294/1/2785/2783/2784/1445/8525/5478/2771/7410/5580/7409/5154/3932/7076/8527/3710/801/5781/2151/2791/2147/928/5170/5590/351/6464/135228/5747/51097/3937/7424/2316/3674/409/6915/7277/10451/221955/334/10447/150/10257/51706/308/6850/8503/6403/4067/81/9948/998/3481/2786/6654/5473/8407/387/29789/10916/5595/139322/7066/151/5321/54331/59345/207/26090/7422/51764/94235/3708/5196/3827/1950/55970/5216/2767/5768/346562/152/6647/4352/27040/2793/23533/7078/55664/391/2/1398/88/5906/3479/5155/5296/5581/213/5660/9630/7057/9002/2207/6814/2790/10672 170 Influenza_A_virus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 65/4622 79/10654 1.1468730993191996e-12 7.0014349032674284e-12 2.746591058355794e-12 2074/5982/7507/5431/5435/9978/5433/10980/2965/5439/10987/2067/6117/10714/91603/7314/6118/5438/5985/2068/5984/6233/7874/5424/8451/10450/5434/5436/7515/54107/8450/4331/5425/5111/6119/5427/1161/1642/2071/51426/2873/7311/8533/5983/5432/51138/56655/9318/5440/902/27339/5430/57804/5441/7316/5426/5437/2033/2968/56949/9716/5981/1022/8178/50813 65 Influenza_A_virus R-HSA-2408522 Selenoamino acid metabolism 89/4622 118/10654 1.1617608730848947e-12 7.061485654663838e-12 2.7701483518408704e-12 6158/6138/6227/6206/6234/6191/6128/6132/6129/6176/6224/6146/6154/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/6208/6170/7296/6203/6147/4143/6222/2936/6134/6155/6231/6142/9061/23521/6207/6233/51091/6188/6122/6230/6194/6166/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6159/6217/6152/51065/6141/6164/79048/6209/11224/6165/6130/6204/6228/51540/7965/6124/6189/6135/6201/6161/6133 89 Influenza_A_virus R-HSA-4615885 SUMOylation of DNA replication proteins 42/4622 45/10654 1.4467547619003033e-12 8.755684662929108e-12 3.434765235589238e-12 23165/9212/348995/6613/57122/23511/6790/23279/23225/9972/6612/8021/55746/7150/51588/3619/7153/332/10762/79902/9883/7155/6396/129401/4928/5903/55706/7175/5111/4927/8086/7329/5905/81929/55143/9631/79023/23636/53371/9688/7341/8480 42 Influenza_A_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 36/4622 37/10654 1.7427530451718495e-12 1.046834630126806e-11 4.1066248196375715e-12 11200/472/639/4194/8900/2475/5518/51230/7314/5515/6446/117584/890/983/5519/10000/900/7157/6233/7874/253260/5170/1029/80196/64223/1616/208/79109/7311/5516/1017/207/7316/9099/5527/4193 36 Influenza_A_virus R-HSA-72649 Translation initiation complex formation 51/4622 58/10654 1.752212471027701e-12 1.046834630126806e-11 4.1066248196375715e-12 6227/6206/1965/6234/6191/8668/6224/8662/26986/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/8663/8894/1981/6207/1977/6233/51386/6188/1968/6230/6194/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/6209/6204/6228/3646/6189/6201 51 Influenza_A_virus R-HSA-72702 Ribosomal scanning and start codon recognition 51/4622 58/10654 1.752212471027701e-12 1.046834630126806e-11 4.1066248196375715e-12 6227/6206/1965/6234/6191/8668/6224/8662/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/8663/8894/1981/6207/1977/6233/51386/6188/1968/6230/6194/1983/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/6209/6204/6228/3646/6189/6201 51 Influenza_A_virus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 39/4622 41/10654 1.799491806710047e-12 1.0705061896938918e-11 4.199485918458834e-12 23165/348995/57122/23511/81608/23279/23225/9972/8021/55746/53981/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10898/10482/51692/8086/22916/81929/9631/29894/79023/23636/4686/8189/53371/9688/10189/8480/55339 39 Influenza_A_virus R-HSA-73893 DNA Damage Bypass 44/4622 48/10654 2.133381832294916e-12 1.2637575430289375e-11 4.957591144628239e-12 56852/5982/9978/25898/57599/6117/10714/55666/7314/51514/6118/9636/11201/51455/5985/5984/6233/5424/8451/124739/54107/7706/8450/5425/5111/6119/5427/1642/5429/9246/51426/7311/7318/5983/56655/57804/7320/7316/5426/9100/10459/7415/7398/5981 44 Influenza_A_virus R-HSA-2871796 FCERI mediated MAPK activation 32/4622 32/10654 2.33173397298759e-12 1.36391803106136e-11 5.350510459927481e-12 3725/4893/5335/2885/3845/3265/5062/5879/5601/5336/5594/4214/7410/7409/2353/6464/2205/3937/10451/2206/6850/4067/5602/6654/5058/6416/5595/9402/27040/5609/5599/2207 32 Influenza_A_virus R-HSA-392518 Signal amplification 32/4622 32/10654 2.33173397298759e-12 1.36391803106136e-11 5.350510459927481e-12 2788/64805/2770/2769/5028/1432/2782/2776/2773/2787/10681/2792/6714/2785/2783/2784/2771/2791/6915/2786/5321/54331/59345/51764/94235/55970/2767/346562/2793/9630/2790/10672 32 Influenza_A_virus R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 32/4622 32/10654 2.33173397298759e-12 1.36391803106136e-11 5.350510459927481e-12 2788/2149/2769/408/2768/2782/2776/2787/5594/10681/2792/6714/2785/2783/2784/2151/2791/2147/409/2786/5595/54331/59345/51764/94235/55970/2767/2793/9630/9002/2790/10672 32 Influenza_A_virus R-HSA-448424 Interleukin-17 signaling 60/4622 72/10654 2.89990468173046e-12 1.689194477107993e-11 6.626536575357763e-12 8454/3605/3725/9252/4790/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/257397/8945/1326/5601/5606/8767/1849/5594/23118/8517/5528/9261/5519/5598/6195/10454/6233/2353/5600/5608/1846/387522/79155/7867/64127/5602/3656/7189/7311/6416/5595/5516/1147/6885/5604/10392/6500/7316/7335/4205/23291/5609/1385/5599 60 Influenza_A_virus R-HSA-6782135 Dual incision in TC-NER 56/4622 66/10654 3.4948920750956378e-12 2.0273274360928222e-11 7.952997471608768e-12 2074/5982/7507/5431/5435/9978/5433/2965/5439/2067/6117/10714/91603/7314/6118/5438/5985/2068/5984/6233/7874/5424/8451/10450/5434/5436/54107/8450/4331/5425/5111/6119/5427/1161/1642/2071/51426/7311/5983/5432/56655/5440/902/27339/5430/57804/5441/7316/5426/5437/2033/2968/56949/9716/5981/1022 56 Influenza_A_virus R-HSA-6784531 tRNA processing in the nucleus 50/4622 57/10654 3.578879778062291e-12 2.0674685660045795e-11 8.110467004656172e-12 23165/10557/348995/57122/23511/11260/23279/11102/23225/9972/8021/10799/51367/55746/54913/10775/10940/10248/10762/1478/79042/79902/9883/10556/1653/6396/129401/80746/79897/4928/5903/55706/7175/116461/4927/10898/5901/8086/283989/81929/9631/29894/79023/23636/53371/10978/283742/9688/51493/8480 50 Influenza_A_virus R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 35/4622 36/10654 3.927311903941086e-12 2.2501565744711635e-11 8.827133312999595e-12 71/51517/147179/10094/8976/2885/3071/5879/26999/25/10093/10006/5594/7456/10810/23191/10109/10787/5747/10152/10092/10163/55845/998/695/10097/60/5595/4690/10458/10552/8936/10096/7454/10095 35 Influenza_A_virus R-HSA-6804757 Regulation of TP53 Degradation 35/4622 36/10654 3.927311903941086e-12 2.2501565744711635e-11 8.827133312999595e-12 11200/472/4194/8900/2475/5518/51230/7314/5515/6446/117584/890/983/5519/10000/900/7157/6233/7874/253260/5170/1029/80196/64223/1616/208/79109/7311/5516/1017/207/7316/9099/5527/4193 35 Influenza_A_virus R-HSA-4570464 SUMOylation of RNA binding proteins 43/4622 47/10654 4.537272638861271e-12 2.589023326174717e-11 1.0156472802778614e-11 1912/23165/6045/80012/348995/6613/57122/23511/3190/1911/23279/23225/57332/9972/8021/55746/51602/10762/79902/9883/84733/6396/129401/7703/6015/4928/5903/55706/7175/8535/4927/8086/7329/648/81929/9631/79023/23636/3183/53371/9688/7341/8480 43 Influenza_A_virus R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 45/4622 50/10654 5.790941317292771e-12 3.2909495778761355e-11 1.2910057451046357e-11 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/2209/5706/5714/5688/5687/5708/5704/5694/5684/5720/5690/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 45 Influenza_A_virus R-HSA-390466 Chaperonin-mediated protein folding 74/4622 95/10654 5.9351177984395006e-12 3.359228616282762e-11 1.3177909111387088e-11 2788/6000/9134/1459/2770/51807/10528/1460/10381/10576/1457/7846/2782/10574/6468/10564/54461/10693/8877/2773/2787/79861/10575/10681/898/10517/8786/2792/26985/2785/10376/2783/26190/2784/10238/7157/2771/83752/2791/26224/84617/2629/8237/10382/7277/63971/6774/26272/26270/347733/55135/5082/2786/10383/60/84790/22948/7280/9628/10694/8841/54331/22803/59345/51764/94235/7203/908/55970/346562/2793/6950/55294/2790 74 Influenza_A_virus R-HSA-191859 snRNP Assembly 47/4622 53/10654 6.733674166666555e-12 3.780592965863391e-11 1.483087821108973e-11 23165/6633/6606/8487/348995/57122/23511/23279/23225/79084/9972/8021/55746/96764/10762/79902/9883/6636/10419/6396/129401/50628/4928/6635/5903/6632/55706/7175/6637/4927/51808/8086/22916/81929/11218/9631/79023/23636/10073/4686/53371/9688/1207/6634/8480/6628/79760 47 Influenza_A_virus R-HSA-194441 Metabolism of non-coding RNA 47/4622 53/10654 6.733674166666555e-12 3.780592965863391e-11 1.483087821108973e-11 23165/6633/6606/8487/348995/57122/23511/23279/23225/79084/9972/8021/55746/96764/10762/79902/9883/6636/10419/6396/129401/50628/4928/6635/5903/6632/55706/7175/6637/4927/51808/8086/22916/81929/11218/9631/79023/23636/10073/4686/53371/9688/1207/6634/8480/6628/79760 47 Influenza_A_virus R-HSA-5655253 Signaling by FGFR2 in disease 40/4622 43/10654 6.7665747745210364e-12 3.783868613912163e-11 1.4843728242212462e-11 5295/4893/5335/5431/5435/5433/5439/2885/2252/3845/3265/5290/8823/8074/5438/2249/2248/2247/2246/2251/2963/5434/5436/2263/2962/6654/2549/5432/22916/5440/5430/8817/5441/2254/4686/26281/10818/5437/2255/27006 40 Influenza_A_virus R-HSA-1852241 Organelle biogenesis and maintenance 186/4622 296/10654 6.8822707579939174e-12 3.809302014405874e-11 1.4943500862174986e-11 5563/79738/79867/55735/79718/7531/11190/203068/54801/51807/85302/347688/79441/53632/10381/5116/3313/5048/10576/5469/22832/10989/60412/8655/6010/89891/9702/132320/1432/1387/25813/7846/7840/6907/2101/11064/84902/2847/10499/5518/1386/55835/9572/85441/3054/23332/7019/93323/814/96764/79861/10575/1454/112752/23408/51422/10013/54806/5465/9727/91147/54927/983/64784/79959/8729/10376/10540/11336/117177/57545/26005/54930/54820/23322/6742/378/5600/1453/6300/801/9793/4218/133522/140735/57576/84617/5442/11258/22981/8636/54903/80776/3842/7532/55125/10382/6753/23410/121441/7277/26146/9814/4209/23354/146057/9738/1639/84303/55722/4957/50807/5566/5571/7283/347733/4580/22919/27077/22994/4867/6648/1069/211/10651/5577/10383/5347/403/84790/22948/80184/22897/5564/23373/5565/5108/261734/57787/7280/10806/9657/1778/55770/139322/115106/10694/22995/55559/8841/10142/6608/51134/95681/200186/79989/7203/1781/80321/8766/9611/23409/79598/54205/149371/10121/347240/84131/6950/3320/79600/10733/6256/4751/10498/80254/1385/26123/9662/55142/8195/8648/8481/51259/55755/10891 186 Influenza_A_virus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 55/4622 65/10654 6.893801213481302e-12 3.809302014405874e-11 1.4943500862174986e-11 2074/5982/5431/5435/9978/5433/2965/5439/6117/10714/91603/7314/6118/5438/5985/2068/5984/6233/7874/5424/8451/10450/5434/5436/7515/54107/8450/4331/5425/5111/6119/5427/1161/1642/2071/51426/7311/5983/5432/56655/5440/902/27339/5430/57804/5441/7316/5426/5437/2033/2968/56949/9716/5981/1022 55 Influenza_A_virus R-HSA-9614085 FOXO-mediated transcription 55/4622 65/10654 6.893801213481302e-12 3.809302014405874e-11 1.4943500862174986e-11 2308/857/2290/65018/57060/356/10971/7295/2810/84676/4089/1647/1387/4088/10628/4801/3630/23411/7534/847/5934/5443/8850/10000/3066/604/5105/7532/4303/23410/4287/4800/901/9314/10370/2908/6794/4852/6648/4087/208/25942/7529/27113/2309/10018/4802/207/1027/6720/1026/2033/3065/91584/10891 55 Influenza_A_virus R-HSA-429914 Deadenylation-dependent mRNA decay 49/4622 56/10654 7.291977144497152e-12 4.013458286616937e-11 1.5744384965947023e-11 5393/80153/23404/26986/28960/219988/25904/1973/10767/55571/11340/57472/85456/29883/80349/51690/11157/1981/1977/23016/118460/9924/23644/5073/27258/4850/255967/57819/246175/4848/23019/23658/1975/51010/56915/1974/167227/22894/1656/27257/4849/25804/9337/55802/51013/196513/9775/54464/54512 49 Influenza_A_virus R-HSA-2682334 EPH-Ephrin signaling 72/4622 92/10654 7.631041694867904e-12 4.1836063880099334e-11 1.6411858505784017e-11 71/2042/1947/1212/23385/2051/10094/2050/2047/2534/9475/1948/4628/8976/6093/163/284656/1759/8874/3265/5062/5879/1072/161/10093/5921/2046/6453/4313/2041/102/6714/5664/2043/7525/1942/7410/1213/1211/1175/10109/5663/1173/2904/5747/7074/10451/4318/160/8218/10092/4067/5063/6386/998/2048/10097/387/60/5058/3984/4627/3985/6383/10398/10552/4637/1946/10096/103910/10095/1969 72 Influenza_A_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 60/4622 73/10654 9.397878419607031e-12 5.132122668207277e-11 2.0132790528845657e-11 892/7321/4738/9372/8239/9612/56937/4609/4089/22938/23327/4088/5499/1030/9110/7040/7314/5054/7027/6497/51592/50848/7323/6667/4092/11171/7046/2280/9958/9040/6233/7514/1025/57530/5500/4221/5590/5501/1024/60436/23645/8812/1874/142/905/4087/7048/7311/387/57154/10273/64750/54778/7316/9611/5933/867/3065/56288/25937 60 Influenza_A_virus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 30/4622 30/10654 1.2482600510399701e-11 6.790146114217426e-11 2.6637046348221362e-11 56852/5982/9978/57599/6117/10714/7314/51514/6118/5985/5984/6233/5424/8451/54107/8450/5425/5111/6119/5427/1642/7311/5983/56655/57804/7320/7316/5426/7398/5981 30 Influenza_A_virus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 39/4622 42/10654 1.4595736398817165e-11 7.908852513777673e-11 3.102561674330373e-11 23165/348995/57122/23511/81608/23279/23225/9972/8021/55746/53981/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10898/10482/51692/8086/22916/81929/9631/29894/79023/23636/4686/8189/53371/9688/10189/8480/55339 39 Influenza_A_virus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 36/4622 38/10654 1.9203483239739695e-11 1.0365432266083435e-10 4.066252699818891e-11 23165/348995/57122/23511/23279/23225/7428/5371/9972/8021/55746/51588/10762/79902/9883/9063/6396/129401/8554/4928/5903/55706/7175/4927/8086/7329/81929/9631/79023/23636/53371/9688/7341/5987/8480/4193 36 Influenza_A_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 33/4622 34/10654 1.9891648401951255e-11 1.0695586333049175e-10 4.1957687519905283e-011 7321/9140/9474/3093/64135/83737/7187/1540/7314/29110/9636/7323/23586/7128/3661/51191/6233/55593/84282/54476/7706/9246/7311/7318/79671/5094/9641/57506/84166/7316/7322/54941/5300 33 Influenza_A_virus R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 45/4622 51/10654 2.8477244707303763e-11 1.5253328774256958e-10 5.983724336561912e-11 6227/6206/1965/6234/6191/8668/6224/8662/6202/6218/3921/8665/6208/6203/8666/6222/8667/6231/8663/8894/6207/6233/51386/6188/1968/6230/6194/6232/6193/6210/6229/6205/6235/6223/8664/6187/6217/51065/10480/6209/6204/6228/3646/6189/6201 45 Influenza_A_virus R-HSA-933541 TRAF6 mediated IRF7 activation 29/4622 29/10654 2.8876035363160643e-11 1.5407899785381136e-10 6.044360957897427e-11 3443/3442/80143/1387/64135/3445/29110/3444/23586/3447/3451/3448/3661/3439/10010/84282/3452/3446/3665/7706/3440/7189/9641/3456/3441/7186/57506/3449/2033 29 Influenza_A_virus R-HSA-74751 Insulin receptor signalling cascade 47/4622 54/10654 3.0040192417300484e-11 1.5968132699386341e-10 6.264134580513729e-11 5295/3643/4893/5291/9965/2264/3630/2885/8660/9846/2252/3845/3265/54106/5290/3667/8823/5594/8074/2260/2249/2248/2247/2246/2251/5781/30849/5170/6464/2322/5140/2263/208/6654/2549/5595/8817/2254/152831/5289/26281/10818/2261/2255/27006/5296/2887 47 Influenza_A_virus R-HSA-5654743 Signaling by FGFR4 38/4622 41/10654 3.1425701199387293e-11 1.664133722603918e-10 6.528225807368732e-11 5295/4893/5335/8569/9965/2264/2885/5518/3845/3265/7314/5515/5290/8823/5594/8074/2249/6714/2247/6233/2246/2251/5781/6464/673/6654/7311/2549/5595/5516/8817/10817/2254/7316/152831/26281/10818/867 38 Influenza_A_virus R-HSA-9612973 Autophagy 87/4622 119/10654 3.7841849434856315e-11 1.9963360569784577e-10 7.831421471920612e-11 5563/65018/1459/1915/27243/9140/8878/1460/53632/84938/5116/115201/9474/8655/1457/51271/3043/3920/9776/55054/55062/2475/84557/3312/11315/92421/7314/137492/64422/139341/25978/51160/60673/9821/51422/7249/10533/10013/91782/79720/192111/440738/6714/8408/84971/6233/9804/30849/57521/140735/7405/79065/22863/7416/26100/64223/5571/128866/6009/3326/7311/5562/93343/11345/55626/7251/5564/5565/7248/11337/10452/8897/1080/64419/7316/83734/11152/5289/8678/56993/3320/81631/10542/23710/54543/7431/23192 87 Influenza_A_virus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 66/4622 84/10654 4.169184681163313e-11 2.1911730016038764e-10 8.595746809996384e-11 10445/5982/6613/7507/9978/85015/10980/2965/10987/2067/6612/6117/7334/10714/7314/6118/83444/86/1643/29844/5985/2068/5984/6233/8607/5424/5886/8451/8554/7515/54107/8450/4331/5425/5111/6119/5427/1642/142/2071/1069/7329/51426/2873/7311/60/8533/5983/51138/7528/56655/9318/902/57804/7336/54778/7316/5426/7341/4798/2968/5887/5981/1022/50813/7508 66 Influenza_A_virus R-HSA-5685938 HDR through Single Strand Annealing (SSA) 35/4622 37/10654 4.215709193240223e-11 2.2073263865729708e-10 8.65911488144355e-11 83990/9156/1763/7486/5982/472/4683/84126/2067/672/6117/83695/6118/25/5888/116028/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/5983/5893/5883/10111/545/5932/7156 35 Influenza_A_virus R-HSA-5617833 Cilium Assembly 133/4622 201/10654 4.260585963930574e-11 2.2224996931249786e-10 8.718638205843791e-11 79738/79867/7531/11190/203068/54801/51807/85302/347688/79441/10381/5116/5048/10576/22832/60412/8655/6010/89891/9702/132320/7846/7840/11064/84902/2847/5518/55835/23332/93323/79861/10575/1454/112752/10013/54806/9727/91147/983/79959/8729/10376/10540/11336/117177/57545/26005/54930/54820/23322/378/1453/9793/4218/140735/57576/84617/11258/22981/8636/54903/80776/3842/7532/55125/10382/6753/121441/7277/26146/9814/23354/146057/9738/1639/55722/4957/50807/5566/7283/347733/22919/27077/22994/4867/1069/5577/10383/5347/403/84790/22948/80184/22897/5108/261734/57787/7280/10806/9657/1778/55770/115106/10694/22995/55559/10142/6608/51134/95681/79989/7203/1781/80321/8766/79598/149371/10121/347240/84131/6950/3320/79600/10733/4751/80254/26123/9662/55142/8195/8481/51259/55755 133 Influenza_A_virus R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 40/4622 44/10654 4.3117650359725115e-11 2.2408355094013276e-10 8.790567731331163e-11 834/79370/55367/472/1387/51499/7159/637/27166/23368/332/64065/8797/7157/604/63970/839/317/5875/55240/5366/84883/147923/843/94241/8626/7161/10397/8795/665/27113/9540/8793/58484/3486/355/8794/124446/5876/581 40 Influenza_A_virus R-HSA-163359 Glucagon signaling in metabolic regulation 32/4622 33/10654 4.470422676172385e-11 2.3146855189959237e-10 9.080273739905701e-11 2788/107/2782/2787/5567/112/5573/111/2785/2783/2784/196883/115/2791/2642/113/5566/2641/2786/5577/109/54331/5575/59345/51764/94235/114/108/55970/2778/5576/2790 32 Influenza_A_virus R-HSA-351202 Metabolism of polyamines 50/4622 59/10654 5.6823634402938936e-11 2.9313446824837134e-10 1.1499364351886265e-10 5689/5682/54498/143471/5705/5709/5695/5711/4946/5683/5699/5702/5696/5691/5718/1728/51582/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6303/5706/4947/5714/5688/5687/5708/5704/5694/5684/5720/5690/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 50 Influenza_A_virus R-HSA-2428924 IGF1R signaling cascade 46/4622 53/10654 6.072676856679116e-11 3.1211772961902224e-10 1.2244058213350693e-10 5295/4893/5291/9965/2264/2885/8660/9846/2252/3845/3265/54106/5290/3667/8823/8074/2260/2249/2248/2247/8471/2246/2251/5781/30849/5170/6464/2322/5140/2263/3481/208/6654/2549/3480/8817/2254/152831/5289/26281/10818/2261/2255/27006/3479/5296 46 Influenza_A_virus R-HSA-391251 Protein folding 76/4622 101/10654 6.365475520684314e-11 3.2596830688339447e-10 1.2787402144887324e-10 2788/6000/9134/1459/2770/51807/10528/1460/10381/10576/1457/7846/2782/10574/6468/10564/54461/10693/8877/2773/2787/79861/10575/10681/898/10517/8786/2792/26985/2785/10376/2783/26190/2784/10238/7157/2771/83752/2791/6904/26224/84617/2629/8237/10382/7277/63971/6774/26272/26270/347733/55135/5082/2786/10383/60/84790/22948/7280/9628/10694/8841/54331/22803/59345/51764/94235/7203/908/55970/346562/1155/2793/6950/55294/2790 76 Influenza_A_virus R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 39/4622 43/10654 9.093006223570378e-11 4.63942434326693e-10 1.819998556465681e-10 2788/360/107/554/2782/2787/5567/10681/112/5573/111/2792/2785/2783/2784/196883/115/2791/359/113/5566/2786/5577/109/54331/5575/59345/51764/94235/114/108/8766/55970/2778/2793/5576/4645/551/2790 39 Influenza_A_virus R-HSA-168638 NOD1/2 Signaling Pathway 34/4622 36/10654 9.240242183031442e-11 4.680383540535491e-10 1.8360664291988488e-10 834/1432/5603/83737/3654/7334/1540/3551/7314/257397/8767/23118/841/8517/7128/837/10454/6233/5600/6300/5608/387522/330/64127/3656/7189/7311/1147/6885/842/10392/7316/7335/329 34 Influenza_A_virus R-HSA-177243 Interactions of Rev with host cellular proteins 34/4622 36/10654 9.240242183031442e-11 4.680383540535491e-10 1.8360664291988488e-10 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/5902/7514/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/1104/5905/3837/81929/9631/79023/23636/53371/9688/8480 34 Influenza_A_virus R-HSA-397795 G-protein beta:gamma signalling 31/4622 32/10654 1.0036715510170757e-10 5.047240389647021e-10 1.9799806061336485e-10 2788/5331/2782/2787/10681/2792/146850/10000/5294/2785/2783/2784/2791/5170/23236/998/695/2786/208/387/5058/54331/59345/207/51764/94235/5330/55970/2793/23533/2790 31 Influenza_A_virus R-HSA-5656169 Termination of translesion DNA synthesis 31/4622 32/10654 1.0036715510170757e-10 5.047240389647021e-10 1.9799806061336485e-10 5982/6117/10714/7314/6118/9636/11201/51455/5985/5984/6233/5424/124739/54107/7706/5425/5111/6119/5427/5429/9246/51426/7311/7318/5983/56655/57804/7316/5426/9100/5981 31 Influenza_A_virus R-HSA-2428928 IRS-related events triggered by IGF1R 45/4622 52/10654 1.2241414768137366e-10 6.133870195647325e-10 2.406254327183387e-10 5295/4893/5291/9965/2264/2885/8660/9846/2252/3845/3265/54106/5290/3667/8823/8074/2260/2249/2248/2247/8471/2246/2251/5781/30849/5170/2322/5140/2263/3481/208/6654/2549/3480/8817/2254/152831/5289/26281/10818/2261/2255/27006/3479/5296 45 Influenza_A_virus R-HSA-912526 Interleukin receptor SHC signaling 27/4622 27/10654 1.5446907666614304e-10 7.712420327830999e-10 3.02550334372408e-10 5295/5777/1437/5291/3558/3717/3563/2885/9846/3635/5290/1439/3718/3567/3562/6464/1438/8503/3636/6654/3716/5293/3561/3568/3560/5296/3559 27 Influenza_A_virus R-HSA-168253 Host Interactions with Influenza Factors 38/4622 42/10654 1.9131036680480553e-10 9.517860953491748e-10 3.7337591723282895e-10 3839/23165/348995/57122/23511/23279/23225/3836/9972/8021/7040/55746/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/293/4927/10898/3840/8086/3837/81929/9631/79023/23636/53371/9688/8480 38 Influenza_A_virus R-HSA-674695 RNA Polymerase II Pre-transcription Events 65/4622 84/10654 1.9458814244893506e-10 9.646603657574864e-10 3.7842636138818657e-10 6884/6875/6874/5431/5435/5433/2965/5439/6873/6881/51616/11198/51497/4300/80349/2959/5438/83860/2068/1025/55677/6883/6829/123169/25920/85403/2963/5434/5436/9646/6878/79577/4331/8148/2962/4298/54457/8812/905/2071/27125/6880/6908/6882/2961/5432/22916/55840/6877/5440/902/6830/5430/6749/5441/4686/6872/6879/9150/54623/5437/2968/138474/1022/8178 65 Influenza_A_virus R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 46/4622 54/10654 2.371745814263627e-10 1.1716256707917138e-9 4.5961672651342743e-10 5295/4893/5291/9965/2264/2885/8660/9846/2252/3845/3265/54106/5290/3667/8823/8074/2260/2249/2248/2247/8471/2246/2251/5781/30849/5170/6464/2322/5140/2263/3481/208/6654/2549/3480/8817/2254/152831/5289/26281/10818/2261/2255/27006/3479/5296 46 Influenza_A_virus R-HSA-5358346 Hedgehog ligand biogenesis 53/4622 65/10654 2.7990230398135604e-10 1.3778289470631542e-9 5.405081555755616e-10 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/6469/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721/5034 53 Influenza_A_virus R-HSA-912694 Regulation of IFNA signaling 26/4622 26/10654 3.572013374255374e-10 1.752166560424215e-9 6.873569595520036e-10 3443/5777/3442/5770/9021/11274/3445/3444/3447/3451/3448/3439/3452/6773/7297/5781/3446/3455/6772/8651/3440/3454/3716/3456/3441/3449 26 Influenza_A_virus R-HSA-5685942 HDR through Homologous Recombination (HRR) 54/4622 67/10654 4.3805918930091166e-10 2.1338515329450943e-9 8.370880571225015e-10 83990/9156/1763/7486/5982/472/4683/84126/672/6117/10714/83695/7314/6118/5888/116028/7517/5985/5984/6233/5884/5810/5424/80010/54107/580/11073/5425/641/5111/6119/3364/10524/5427/144715/5889/5429/1111/79728/51426/7311/5983/56655/5883/10111/57804/675/545/7316/5426/23514/5932/7156/5981 54 Influenza_A_virus R-HSA-159227 Transport of the SLBP independent Mature mRNA 32/4622 34/10654 4.417054805180879e-10 2.1338515329450943e-9 8.370880571225015e-10 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10482/8086/22916/81929/9631/79023/23636/4686/53371/9688/10189/8480 32 Influenza_A_virus R-HSA-165054 Rev-mediated nuclear export of HIV RNA 32/4622 34/10654 4.417054805180879e-10 2.1338515329450943e-9 8.370880571225015e-10 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/5902/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/1104/5905/81929/9631/79023/23636/53371/9688/8480 32 Influenza_A_virus R-HSA-4085377 SUMOylation of SUMOylation proteins 32/4622 34/10654 4.417054805180879e-10 2.1338515329450943e-9 8.370880571225015e-10 23165/348995/6613/57122/23511/23279/23225/9972/8021/55746/51588/10762/79902/9883/6396/129401/4928/5903/55706/7175/10210/4927/8086/7329/81929/9631/79023/23636/53371/9688/7341/8480 32 Influenza_A_virus R-HSA-5358351 Signaling by Hedgehog 102/4622 149/10654 4.426444524707277e-10 2.1338515329450943e-9 8.370880571225015e-10 8454/5689/5682/22873/1452/143471/10381/5705/8452/5709/9978/5695/107/5711/7846/5683/408/5699/6400/5702/83737/6469/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/112/5573/5727/8650/111/9861/2932/5698/5692/5713/10376/5710/5719/6233/23322/196883/115/84617/54903/10382/409/79577/7277/5706/113/84447/5714/5566/5688/5687/347733/5708/5577/5704/7311/10383/84790/5694/7280/109/57154/5684/5720/2735/5575/6608/5690/5717/9491/6500/114/10197/108/64750/7316/10213/2778/7415/5715/5701/5576/5685/5686/5716/23432/8481/5693/2622/5721/5034 102 Influenza_A_virus R-HSA-1632852 Macroautophagy 71/4622 95/10654 4.610677258381999e-10 2.213262426846214e-9 8.682401358232645e-10 5563/65018/1459/27243/9140/8878/1460/53632/84938/115201/9474/8655/1457/9776/55054/55062/2475/84557/3312/92421/7314/64422/139341/25978/60673/9821/51422/7249/10533/91782/192111/440738/6714/8408/84971/6233/9804/30849/57521/140735/7405/79065/22863/7416/26100/64223/5571/128866/6009/7311/5562/11345/55626/5564/5565/7248/11337/10452/8897/64419/7316/83734/11152/5289/8678/56993/81631/10542/23710/54543/23192 71 Influenza_A_virus R-HSA-69231 Cyclin D associated events in G1 39/4622 44/10654 4.63866874868341e-10 2.213262426846214e-9 8.682401358232645e-10 8454/5925/1869/5753/1031/3717/5520/1030/5518/7314/5515/25/7027/5934/6714/5519/6502/595/896/6233/1163/1019/1029/4331/4067/1874/7311/5516/894/902/1027/6500/7316/1026/5933/1871/1021/1022/1028 39 Influenza_A_virus R-HSA-69236 G1 Phase 39/4622 44/10654 4.63866874868341e-10 2.213262426846214e-9 8.682401358232645e-10 8454/5925/1869/5753/1031/3717/5520/1030/5518/7314/5515/25/7027/5934/6714/5519/6502/595/896/6233/1163/1019/1029/4331/4067/1874/7311/5516/894/902/1027/6500/7316/1026/5933/1871/1021/1022/1028 39 Influenza_A_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 45/4622 53/10654 4.694056552009004e-10 2.232071789016526e-9 8.756188555663055e-10 7531/10971/7533/2810/1869/8655/836/7159/637/578/23368/7027/5594/841/7534/4836/22900/598/10000/708/3002/7157/331/57099/317/140735/1029/572/7532/6774/5366/8626/208/7161/7529/5595/27113/596/10018/842/207/54205/5534/581/5599 45 Influenza_A_virus R-HSA-5632684 Hedgehog 'on' state 65/4622 85/10654 4.772690916843204e-10 2.2617701361853556e-9 8.872692123729917e-10 5689/5682/22873/1452/143471/5705/8452/5709/9978/5695/5711/5683/408/5699/5702/83737/6469/5696/5691/7314/5718/5700/122706/5707/23198/5727/8650/9861/5698/5692/5713/5710/5719/6233/409/79577/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/2735/6608/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/5716/23432/5693/2622/5721 65 Influenza_A_virus R-HSA-167161 HIV Transcription Initiation 41/4622 47/10654 4.933554605958912e-10 2.2913984515383914e-9 8.988920964170635e-10 6884/6875/6874/5431/5435/5433/2965/5439/6873/6881/51616/2959/5438/83860/2068/6883/2963/5434/5436/6878/4331/8148/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/5437/2968/138474/1022 41 Influenza_A_virus R-HSA-167162 RNA Polymerase II HIV Promoter Escape 41/4622 47/10654 4.933554605958912e-10 2.2913984515383914e-9 8.988920964170635e-10 6884/6875/6874/5431/5435/5433/2965/5439/6873/6881/51616/2959/5438/83860/2068/6883/2963/5434/5436/6878/4331/8148/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/5437/2968/138474/1022 41 Influenza_A_virus R-HSA-73776 RNA Polymerase II Promoter Escape 41/4622 47/10654 4.933554605958912e-10 2.2913984515383914e-9 8.988920964170635e-10 6884/6875/6874/5431/5435/5433/2965/5439/6873/6881/51616/2959/5438/83860/2068/6883/2963/5434/5436/6878/4331/8148/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/5437/2968/138474/1022 41 Influenza_A_virus R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 41/4622 47/10654 4.933554605958912e-10 2.2913984515383914e-9 8.988920964170635e-10 6884/6875/6874/5431/5435/5433/2965/5439/6873/6881/51616/2959/5438/83860/2068/6883/2963/5434/5436/6878/4331/8148/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/5437/2968/138474/1022 41 Influenza_A_virus R-HSA-75953 RNA Polymerase II Transcription Initiation 41/4622 47/10654 4.933554605958912e-10 2.2913984515383914e-9 8.988920964170635e-10 6884/6875/6874/5431/5435/5433/2965/5439/6873/6881/51616/2959/5438/83860/2068/6883/2963/5434/5436/6878/4331/8148/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/5437/2968/138474/1022 41 Influenza_A_virus R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 41/4622 47/10654 4.933554605958912e-10 2.2913984515383914e-9 8.988920964170635e-10 6884/6875/6874/5431/5435/5433/2965/5439/6873/6881/51616/2959/5438/83860/2068/6883/2963/5434/5436/6878/4331/8148/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/5437/2968/138474/1022 41 Influenza_A_virus R-HSA-2424491 DAP12 signaling 29/4622 30/10654 5.042856460932299e-10 2.319050438283998e-9 9.097396870310693e-10 5295/4893/5335/7305/5291/3824/54209/567/2534/3822/2885/3133/3845/3265/5879/5290/5336/7410/3932/6464/3937/10451/6850/22914/695/6654/9402/27040/5296 29 Influenza_A_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 29/4622 30/10654 5.042856460932299e-10 2.319050438283998e-9 9.097396870310693e-10 7124/7375/10616/1540/3551/7314/257397/81858/8737/55072/23118/8517/7128/10454/6233/331/8717/330/27005/7311/1147/7186/56957/6885/7316/7132/329/9099/7185 29 Influenza_A_virus R-HSA-6804758 Regulation of TP53 Activity through Acetylation 29/4622 30/10654 5.042856460932299e-10 2.319050438283998e-9 9.097396870310693e-10 64769/84289/29117/5928/1107/5371/8396/23774/3622/79837/27154/57459/10000/7994/3066/7157/5608/7862/9219/5931/1108/54815/208/53615/5305/207/2033/3065/5300 29 Influenza_A_virus R-HSA-8943724 Regulation of PTEN gene transcription 50/4622 61/10654 6.320972511011416e-10 2.8972851050471994e-9 1.1365752125062803e-9 1912/3725/6591/1822/9112/6045/80012/1911/5928/23512/57332/1107/2475/1386/23186/2146/51564/5594/84232/7101/84733/57459/3066/7157/8726/57521/6015/9219/8535/5931/1108/2122/64223/10014/54815/6009/57504/648/23466/53615/5595/8841/5468/5978/57167/1958/6615/3065/23028/10542 50 Influenza_A_virus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 25/4622 25/10654 8.259066816393378e-10 3.736626346057586e-9 1.4658401673789646e-9 11065/7321/8697/51529/29945/51434/9184/29882/7314/996/51433/119504/7324/64682/6233/246184/8881/10393/7311/25906/991/7316/4085/4751/701 25 Influenza_A_virus R-HSA-392451 G beta:gamma signalling through PI3Kgamma 25/4622 25/10654 8.259066816393378e-10 3.736626346057586e-9 1.4658401673789646e-9 2788/2782/2787/10681/2792/146850/10000/5294/2785/2783/2784/2791/5170/2786/208/387/54331/59345/207/51764/94235/55970/2793/23533/2790 25 Influenza_A_virus R-HSA-418592 ADP signalling through P2Y purinoceptor 1 25/4622 25/10654 8.259066816393378e-10 3.736626346057586e-9 1.4658401673789646e-9 2788/2769/5028/1432/2782/2776/2787/10681/2792/6714/2785/2783/2784/2791/2786/5321/54331/59345/51764/94235/55970/2767/2793/9630/2790 25 Influenza_A_virus R-HSA-9006335 Signaling by Erythropoietin 25/4622 25/10654 8.259066816393378e-10 3.736626346057586e-9 1.4658401673789646e-9 5295/4893/5335/5291/6776/3717/2885/2056/8660/3845/3265/1399/5290/5336/5294/2057/7409/6777/6464/2889/4067/6654/5293/2549/23533 25 Influenza_A_virus R-HSA-168276 NS1 Mediated Effects on Host Pathways 36/4622 40/10654 8.405123990217517e-10 3.790439786556158e-9 1.4869506278109768e-9 3839/23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/4927/10898/3840/8086/3837/81929/9631/79023/23636/53371/9688/8480 36 Influenza_A_virus R-HSA-2980766 Nuclear Envelope Breakdown 44/4622 52/10654 9.259973636538508e-10 4.162521911215702e-9 1.6329146267174016e-9 23165/5579/91754/5578/348995/57122/23511/23279/23225/9972/8021/55746/10762/983/79902/9883/7444/2010/64900/23175/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/5347/7112/4000/81929/9631/140609/79023/23636/7443/53371/9688/23399/23592/8480 44 Influenza_A_virus R-HSA-1433557 Signaling by SCF-KIT 38/4622 43/10654 9.542006815299692e-10 4.275553053778516e-9 1.6772555839308839e-9 5295/5777/4893/5578/6776/3717/2534/2885/9846/3845/3265/10603/5879/5290/3815/9306/6714/7525/7409/3932/6777/5781/2241/4318/6774/6772/8651/8503/4067/1111/6654/9402/867/4254/5296/10076/2887/2242 38 Influenza_A_virus R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 31/4622 33/10654 9.631425443714578e-10 4.288131455513688e-9 1.6821899618422042e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/3303/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/3304/81929/9631/79023/23636/53371/9688/8480 31 Influenza_A_virus R-HSA-180746 Nuclear import of Rev protein 31/4622 33/10654 9.631425443714578e-10 4.288131455513688e-9 1.6821899618422042e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/1104/3837/81929/9631/79023/23636/53371/9688/8480 31 Influenza_A_virus R-HSA-73894 DNA Repair 199/4622 334/10654 1.1069042963586936e-9 4.9125466866966785e-9 1.92714164879826e-9 4436/83990/151987/9156/2074/1763/7486/27343/4913/56852/10445/5982/11200/472/6613/7507/5431/5435/2140/9978/5433/85015/10980/64421/4683/2965/25898/165918/84126/54890/5439/10987/8900/8924/57599/2067/672/6612/6117/7334/10973/10714/55666/54386/91603/83695/7314/51514/7014/6118/2176/25/5888/322/328/83444/51588/51720/63967/5531/9636/23583/86/5438/11201/116028/2070/890/1643/7517/9656/51455/29844/5985/2068/7157/5984/4595/4255/6233/7158/6047/55247/8607/7874/5884/5810/5424/5886/8451/8554/10450/8467/80010/124739/3838/5434/5436/2956/7515/54107/7013/4292/7706/580/11073/5591/8450/4331/5425/641/5111/6119/3364/22976/10524/5427/144715/1161/5889/1642/5429/142/1111/2071/55215/1069/7329/9246/79728/51426/2873/7311/7318/4968/23030/60/5536/8533/5983/2175/2547/5432/51138/7528/56655/9318/11284/1017/25913/5440/5893/902/84164/5883/27339/5430/10111/57804/7320/7520/675/51548/545/5441/7336/29086/54778/7316/6996/5426/9100/10459/7415/5395/7341/4798/5437/51008/65057/2033/7398/23514/2968/5932/9025/2189/55120/79184/56949/7156/5887/9716/5599/5981/1022/8178/50813/7508 199 Influenza_A_virus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 35/4622 39/10654 1.7547425716964955e-9 7.738580805147321e-9 3.0357658304960126e-9 5982/25898/6117/10714/55666/7314/6118/9636/11201/51455/5985/5984/6233/5424/124739/54107/7706/5425/5111/6119/5427/5429/9246/51426/7311/7318/5983/56655/57804/7316/5426/9100/10459/7415/5981 35 Influenza_A_virus R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 35/4622 39/10654 1.7547425716964955e-9 7.738580805147321e-9 3.0357658304960126e-9 83990/9156/1763/7486/5982/472/4683/84126/672/6117/83695/6118/5888/116028/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/5889/1111/5983/5883/10111/675/545/5932/7156 35 Influenza_A_virus R-HSA-3371571 HSF1-dependent transactivation 24/4622 24/10654 1.909392785086161e-9 8.367809133387e-9 3.2826056460316444e-9 817/3305/1387/2475/3306/3312/818/3303/84335/3337/3297/57521/1410/64223/26353/3281/816/3326/3304/10728/815/3320/2033/2288 24 Influenza_A_virus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 24/4622 24/10654 1.909392785086161e-9 8.367809133387e-9 3.2826056460316444e-9 1432/3654/7334/7314/257397/5606/8767/23118/8517/9261/10454/6233/5600/5608/387522/7867/64127/3656/7189/7311/6885/10392/7316/7335 24 Influenza_A_virus R-HSA-3928662 EPHB-mediated forward signaling 37/4622 42/10654 1.9570229120312796e-9 8.440550120974633e-9 3.3111411889374174e-9 71/1947/2051/10094/2050/2047/2534/9475/1948/8976/6093/3265/5879/1072/10093/5921/6453/6714/7525/10109/2904/5747/7074/10092/4067/998/2048/10097/387/60/5058/3984/3985/6383/10552/10096/10095 37 Influenza_A_virus R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 37/4622 42/10654 1.9570229120312796e-9 8.440550120974633e-9 3.3111411889374174e-9 83990/9156/1763/7486/5982/472/4683/84126/672/6117/83695/6118/5888/116028/7517/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/5889/1111/79728/5983/5883/10111/675/545/5932/7156 37 Influenza_A_virus R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 37/4622 42/10654 1.9570229120312796e-9 8.440550120974633e-9 3.3111411889374174e-9 2788/6000/1459/2770/1460/10576/1457/2782/10574/10693/2773/2787/10575/10681/8786/2792/2785/2783/2784/2771/2791/5082/2786/22948/9628/10694/54331/59345/51764/94235/7203/908/55970/346562/2793/6950/2790 37 Influenza_A_virus R-HSA-112399 IRS-mediated signalling 41/4622 48/10654 1.9605969311789e-9 8.440550120974633e-9 3.3111411889374174e-9 5295/4893/5291/9965/2264/2885/8660/9846/2252/3845/3265/54106/5290/3667/8823/8074/2260/2249/2248/2247/2246/2251/5781/30849/5170/2322/5140/2263/208/6654/2549/8817/2254/152831/5289/26281/10818/2261/2255/27006/5296 41 Influenza_A_virus R-HSA-418597 G alpha (z) signalling events 41/4622 48/10654 1.9605969311789e-9 8.440550120974633e-9 3.3111411889374174e-9 2788/5579/2770/5578/5582/5583/107/2782/2773/2787/10681/112/111/2792/5588/2785/2783/2784/2771/5580/196883/115/2791/150/113/2786/109/151/54331/59345/51764/94235/114/108/55970/2778/346562/152/2793/5581/2790 41 Influenza_A_virus R-HSA-9006936 Signaling by TGF-beta family members 74/4622 102/10654 1.962216587494103e-9 8.440550120974633e-9 3.3111411889374174e-9 10272/892/7321/4738/9372/130399/8239/9612/56937/4609/4089/22938/23327/4088/5499/1030/9110/7040/7314/5054/7027/6497/51592/50848/7323/91/93/6667/4092/11171/7046/94/2280/9958/9040/6233/7514/1025/8928/57530/4091/5500/4090/4221/4093/5590/9765/269/5501/1024/60436/23645/8812/1874/142/905/4087/7048/7311/387/57154/10273/4086/64750/659/54778/7316/9611/5933/867/3065/657/56288/25937 74 Influenza_A_virus R-HSA-5673000 RAF activation 30/4622 32/10654 2.096098902667766e-9 8.988792226777721e-9 3.5262109405550734e-9 4893/5526/817/5605/3717/4296/5894/5518/4140/3845/3265/5515/818/8844/5528/6714/5519/369/801/673/8315/5529/816/7529/5516/815/5604/5525/5527/5245 30 Influenza_A_virus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 32/4622 35/10654 2.9964197631649837e-9 1.277132569788002e-8 5.01006000195429e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10482/8086/22916/81929/9631/79023/23636/4686/53371/9688/10189/8480 32 Influenza_A_virus R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 32/4622 35/10654 2.9964197631649837e-9 1.277132569788002e-8 5.01006000195429e-9 23165/91754/348995/57122/23511/23279/23225/9972/8021/55746/10762/983/79902/9883/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/81929/9631/140609/79023/23636/53371/9688/8480 32 Influenza_A_virus R-HSA-5655302 Signaling by FGFR1 in disease 34/4622 38/10654 3.6530020496154246e-9 1.5522482873441833e-8 6.089310727402451e-9 5295/4893/11052/5335/9530/613/6776/11064/2885/9846/3845/3265/7750/8805/26127/5290/8074/2260/2249/399687/2247/2246/2251/6777/1523/9208/6774/6772/6654/11160/2549/2254/26281/10818 34 Influenza_A_virus R-HSA-6783783 Interleukin-10 signaling 40/4622 47/10654 3.889913792868709e-9 1.647908934069835e-8 6.464577627064107e-9 729230/7124/1437/3593/5743/941/3383/3576/2920/1435/7133/3606/6347/3569/3592/6367/3627/7076/7850/7297/3557/6351/6774/1440/3552/3716/1234/3586/3554/3553/1230/2919/2357/6352/6348/6364/7132/942/6363/5724 40 Influenza_A_virus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 23/4622 23/10654 4.413732267503995e-9 1.852972285276452e-8 7.269020108644165e-9 11065/7321/8697/51529/29945/51434/29882/7314/996/983/51433/119504/7324/64682/6233/246184/8881/891/10393/7311/25906/991/7316 23 Influenza_A_virus R-HSA-428930 Thromboxane signalling through TP receptor 23/4622 23/10654 4.413732267503995e-9 1.852972285276452e-8 7.269020108644165e-9 2788/2769/2782/2776/2787/10681/2792/2785/2783/2784/2791/6915/2786/54331/59345/51764/94235/55970/2767/2793/9630/2790/10672 23 Influenza_A_virus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 23/4622 23/10654 4.413732267503995e-9 1.852972285276452e-8 7.269020108644165e-9 3654/7334/7314/257397/5601/8767/23118/8517/10454/6233/387522/64127/5602/3656/7189/7311/6416/6885/10392/7316/7335/5609/5599 23 Influenza_A_virus R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 29/4622 31/10654 4.552471869238534e-9 1.899807663640439e-8 7.452750491353579e-9 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/3837/81929/9631/79023/23636/53371/9688/8480 29 Influenza_A_virus R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 29/4622 31/10654 4.552471869238534e-9 1.899807663640439e-8 7.452750491353579e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/81929/9631/79023/23636/53371/9688/8480 29 Influenza_A_virus R-HSA-438064 Post NMDA receptor activation events 61/4622 81/10654 4.698825310014325e-9 1.955046959345246e-8 7.669448579315361e-9 5563/4893/51807/817/347688/53632/10381/107/7846/1741/1739/6196/1740/8874/6197/3845/3265/814/5879/818/79861/5567/5594/51422/5573/6714/10376/6195/5613/801/5170/84617/3838/2904/10382/7277/10645/5566/84254/5571/27330/347733/3084/816/5577/5562/10383/84790/5564/5565/7280/5595/815/5575/114/5576/4137/2066/1742/88/1385 61 Influenza_A_virus R-HSA-72165 mRNA Splicing - Minor Pathway 43/4622 52/10654 6.094388154772781e-9 2.5281764511490648e-8 9.917776756634762e-9 6633/6431/4904/51639/23450/5431/5435/5433/9416/23020/5439/9410/10907/10262/6432/83443/5438/9343/6636/2963/6635/5434/6632/24148/5436/6637/57819/2962/6426/5432/22916/23451/5440/5430/11325/5441/10594/4686/5437/6634/6427/10992/6628 43 Influenza_A_virus R-HSA-422356 Regulation of insulin secretion 59/4622 78/10654 6.311263827683775e-9 2.610398470740212e-8 1.0240325301224686e-8 2788/5331/2740/2770/5578/2769/2782/3630/2776/8826/2181/6513/2787/5567/1131/10681/112/5573/111/2792/2785/2783/2784/2771/6844/2182/3710/2791/150/5566/775/2864/23236/2641/6514/2786/5577/773/54331/5575/59345/776/51764/94235/114/3708/4082/5330/3790/55970/2778/2767/10768/152/2793/5576/5906/9630/2790 59 Influenza_A_virus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 73/4622 102/10654 6.736058513590556e-9 2.777878997639999e-8 1.089733422009216e-8 8454/7124/5689/5682/356/9039/143471/5705/10673/5709/5695/7133/5711/5683/5699/5702/7187/958/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/8741/1896/9861/5698/5692/5713/5710/9040/5719/6233/4791/959/4055/8600/330/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/7186/5690/5717/9491/6500/10197/7316/10213/5715/7132/5701/329/23291/5685/5686/5716/5693/5721 73 Influenza_A_virus R-HSA-5654741 Signaling by FGFR3 35/4622 40/10654 8.154353780419743e-9 3.3528784073608234e-8 1.3152997893494383e-8 5295/4893/5335/8569/2885/5518/3845/3265/7314/5515/5290/8823/5594/8074/2249/6714/2247/6233/2246/5781/6464/673/6654/7311/2549/5595/5516/8817/10817/2254/7316/26281/10818/2261/867 35 Influenza_A_virus R-HSA-400253 Circadian Clock 54/4622 70/10654 8.271506363611184e-9 3.3910750429115644e-8 1.3302839374722725e-8 8454/79718/5936/3091/5469/1387/150094/6907/5499/10499/1386/23411/9572/85441/96764/7314/5054/8945/10135/1454/5465/64784/6233/8864/1453/5500/5187/26224/1374/1407/406/4209/5501/8553/2908/1390/7311/23373/8841/8204/4862/6500/200186/1408/6720/7316/9611/2033/6256/10498/1385/8648/551/10891 54 Influenza_A_virus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 44/4622 54/10654 9.87993836096508e-9 4.03864147035941e-8 1.5843176011273643e-8 2074/7507/5431/5435/9978/5433/10980/2965/5439/10987/91603/7314/5438/2068/6233/7874/8451/10450/5434/5436/8450/4331/1161/1642/2071/2873/7311/8533/5432/51138/9318/5440/902/27339/5430/5441/7316/5437/2033/2968/56949/9716/1022/50813 44 Influenza_A_virus R-HSA-1250196 SHC1 events in ERBB2 signaling 22/4622 22/10654 1.0201478580022286e-8 4.133816537643813e-8 1.6216538032621238e-8 4893/5578/2064/145957/9542/2885/3845/3265/1839/2065/2069/5580/6464/5782/3084/6654/10718/1956/685/1950/2066/5581 22 Influenza_A_virus R-HSA-392170 ADP signalling through P2Y purinoceptor 12 22/4622 22/10654 1.0201478580022286e-8 4.133816537643813e-8 1.6216538032621238e-8 2788/64805/2770/2782/2773/2787/10681/2792/2785/2783/2784/2771/2791/2786/54331/59345/51764/94235/55970/346562/2793/2790 22 Influenza_A_virus R-HSA-912631 Regulation of signaling by CBL 22/4622 22/10654 1.0201478580022286e-8 4.133816537643813e-8 1.6216538032621238e-8 5295/5291/2534/2885/1399/7314/5290/6233/7525/7409/6850/8503/2889/4067/29760/7311/5293/7316/3055/867/1398/5296 22 Influenza_A_virus R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 42/4622 51/10654 1.1714796126729121e-8 4.733319359874945e-8 1.8568326078569733e-8 51807/347688/10381/1780/5048/8655/84516/832/636/7846/2590/51164/79861/23299/5870/10376/10540/140735/84617/2589/11258/1783/10382/93661/55860/830/7277/10671/1639/347733/51143/10383/84790/7280/829/1778/5321/5050/1781/22930/25782/10121 42 Influenza_A_virus R-HSA-1839126 FGFR2 mutant receptor activation 30/4622 33/10654 1.3425662485630732e-8 5.347315143849505e-8 2.0976968526056713e-8 5431/5435/5433/5439/2252/8823/8074/5438/2249/2248/2247/2246/2251/2963/5434/5436/2263/2962/5432/22916/5440/5430/8817/5441/2254/4686/26281/5437/2255/27006 30 Influenza_A_virus R-HSA-202433 Generation of second messenger molecules 30/4622 33/10654 1.3425662485630732e-8 5.347315143849505e-8 2.0976968526056713e-8 5335/3115/3113/3117/3127/5062/3126/916/3702/3932/3120/3937/3123/3122/920/5063/7535/3125/5058/55740/9402/4690/3119/919/27040/915/917/51466/7408/7454 30 Influenza_A_virus R-HSA-2559585 Oncogene Induced Senescence 30/4622 33/10654 1.3425662485630732e-8 5.347315143849505e-8 2.0976968526056713e-8 2077/27327/5925/2114/1869/4194/1031/192669/1030/4343/7314/7027/5594/6667/7157/6233/26523/1019/1029/7311/3397/2113/5595/57690/192670/7316/1871/1021/23112/4193 30 Influenza_A_virus R-HSA-389356 CD28 co-stimulation 30/4622 33/10654 1.3425662485630732e-8 5.347315143849505e-8 2.0976968526056713e-8 5295/941/2534/2885/2475/5062/5879/1326/5290/9020/6714/10000/7525/7409/3932/940/253260/5170/64223/8503/4067/5063/998/208/79109/5058/9402/207/942/5296 30 Influenza_A_virus R-HSA-9022692 Regulation of MECP2 expression and activity 30/4622 33/10654 1.3425662485630732e-8 5.347315143849505e-8 2.0976968526056713e-8 2290/79718/817/9212/27327/28996/9612/6907/192669/4343/814/818/3066/26523/801/3930/5566/816/25942/27161/815/8841/57690/192670/9611/2874/3064/3065/23112/1385 30 Influenza_A_virus R-HSA-3899300 SUMOylation of transcription cofactors 38/4622 45/10654 1.514609967363425e-8 6.015411177199057e-8 2.3597840699651447e-8 1912/6045/80012/6613/28996/9612/1911/1387/57332/115426/10499/6612/11315/3622/51588/1655/84733/10155/9063/7690/7703/6015/8554/8535/4869/10210/10521/1616/7329/25942/648/1487/8204/7341/2033/6294/8648/10891 38 Influenza_A_virus R-HSA-176033 Interactions of Vpr with host cellular proteins 32/4622 36/10654 1.568789340363797e-8 6.212939087333111e-8 2.437272241924969e-8 23165/348995/57122/23511/292/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/293/4927/8086/81929/9631/3159/79023/23636/53371/9688/8480/291 32 Influenza_A_virus R-HSA-73887 Death Receptor Signalling 94/4622 141/10654 1.7268544706274515e-8 6.819611722986376e-8 2.6752636907430934e-8 7124/9639/7984/4790/7531/29/356/7375/9530/8878/1894/23385/10276/4792/9138/836/23365/10616/3654/8874/1540/3551/7314/5879/257397/81858/8737/8767/55072/23118/841/8517/6453/9828/5970/5664/8797/7128/396/10454/3066/6233/7410/7409/26574/8772/331/8717/8743/5663/572/7204/7074/330/10451/27005/50650/843/8837/8567/7189/6654/7311/387/8795/1147/4804/57142/8841/7186/56957/6885/5584/10018/57580/8793/355/11214/23421/4615/7316/4168/23263/50649/9826/7132/329/9099/4803/3065/55512/5599/7185/10672 94 Influenza_A_virus R-HSA-6802957 Oncogenic MAPK signaling 54/4622 71/10654 1.997752641789866e-8 7.867206178090796e-8 3.0862242442476505e-8 4893/71/817/5908/8546/5605/5037/3717/3690/408/4296/5894/8826/4140/3845/3265/4763/818/8805/55750/8844/7094/5594/7414/10533/23164/57085/6714/9061/2335/1445/369/801/57670/283455/3674/409/673/8315/816/56829/60/7529/5595/4000/27044/815/22906/5604/10018/10142/5906/9715/5245 54 Influenza_A_virus R-HSA-186763 Downstream signal transduction 27/4622 29/10654 2.1332421357663375e-8 8.353704498042968e-8 3.27707254233897e-8 5295/4893/5335/5291/6776/2885/9564/3845/3265/1399/5290/5921/6778/6714/5154/6777/5781/6774/6772/2889/5159/6654/4690/1398/5155/5296/5156 27 Influenza_A_virus R-HSA-8863795 Downregulation of ERBB2 signaling 27/4622 29/10654 2.1332421357663375e-8 8.353704498042968e-8 3.27707254233897e-8 26469/2064/145957/4145/9542/7314/1839/2065/2069/9101/10000/6233/5782/3084/208/10718/7311/1956/11140/8065/685/10273/207/7316/1950/3320/2066 27 Influenza_A_virus R-HSA-389513 CTLA4 inhibitory signaling 21/4622 21/10654 2.3575814331966316e-8 9.206421350862824e-8 3.6115846124535285e-8 5526/941/2534/5518/5515/5528/6714/5519/10000/7525/3932/5781/1493/4067/5529/208/5516/5525/207/942/5527 21 Influenza_A_virus R-HSA-437239 Recycling pathway of L1 39/4622 47/10654 2.621618910592127e-8 1.0208978376066277e-7 4.0048774444172356e-8 9252/71/7430/51807/347688/1785/10381/7846/1808/6456/5962/163/6196/1759/6197/161/79861/5594/8650/6714/10376/6195/1213/1211/1175/1173/84617/10382/7277/4478/160/26052/27330/347733/3897/10383/60/84790/7280 39 Influenza_A_virus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 24/4622 25/10654 2.7913059267809767e-8 1.0779684214474601e-7 4.2287594877955484e-8 2308/2475/84335/7249/2932/10000/2931/253260/5170/572/4303/6199/64223/208/79109/1147/2309/842/207/1027/1026/3164/1385/4193 24 Influenza_A_virus R-HSA-9006115 Signaling by NTRK2 (TRKB) 24/4622 25/10654 2.7913059267809767e-8 1.0779684214474601e-7 4.2287594877955484e-8 5295/627/4893/5335/2534/2885/3845/3265/5879/5290/6714/4909/5781/4908/6464/2904/7074/6654/2549/1020/4915/10817/10818/8851 24 Influenza_A_virus R-HSA-937041 IKK complex recruitment mediated by RIP1 24/4622 25/10654 2.7913059267809767e-8 1.0779684214474601e-7 4.2287594877955484e-8 7321/100302736/929/7334/3551/7314/11035/8737/8517/7323/6233/387522/330/7189/7311/23643/1147/7099/7316/7335/7322/329/353376/148022 24 Influenza_A_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 29/4622 32/10654 2.8297410546089086e-8 1.0868071413030919e-7 4.263432878690693e-8 4738/9372/56937/4089/23327/4088/5499/9110/7040/7314/4092/11171/7046/2280/9958/9040/6233/7514/5500/5501/23645/4087/7048/7311/57154/10273/64750/7316/867 29 Influenza_A_virus R-HSA-381042 PERK regulates gene expression 29/4622 32/10654 2.8297410546089086e-8 1.0868071413030919e-7 4.263432878690693e-8 5393/1965/23404/3576/3309/4801/6347/11340/468/8894/9451/8570/23016/118460/1968/5073/1051/4800/22926/51010/56915/167227/22894/440/9709/4802/51013/467/54512 29 Influenza_A_virus R-HSA-109704 PI3K Cascade 37/4622 44/10654 2.9714446584916806e-8 1.1349944351287895e-7 4.4524666870122684e-8 5295/5291/9965/2264/2885/8660/9846/2252/54106/5290/3667/8823/8074/2260/2249/2248/2247/2246/2251/5781/30849/5170/2322/5140/2263/208/2549/8817/2254/152831/5289/26281/10818/2261/2255/27006/5296 37 Influenza_A_virus R-HSA-451927 Interleukin-2 family signaling 37/4622 44/10654 2.9714446584916806e-8 1.1349944351287895e-7 4.4524666870122684e-8 5295/5777/1437/5291/6776/84868/3558/3717/3563/2885/9846/3600/3635/5290/1439/3718/3567/3932/6777/3562/6464/1438/6774/6850/6772/8503/3636/6654/3716/5293/2185/3561/3578/3568/3560/5296/3559 37 Influenza_A_virus R-HSA-8853659 RET signaling 35/4622 41/10654 3.238050587826226e-8 1.2334590522564206e-7 4.838733274795536e-8 5295/2674/1796/5335/5291/5578/2668/2885/8660/9846/5623/5290/5567/4902/6714/5598/64096/9260/5781/6464/2675/2676/5566/8503/6654/5293/2549/85358/5909/10818/5979/9048/5296/2887/9046 35 Influenza_A_virus R-HSA-5689896 Ovarian tumor domain proteases 33/4622 38/10654 3.3514207933161515e-8 1.2731756165912988e-7 4.994537280657079e-8 7321/324/64135/7187/23252/7314/8737/8767/55611/8517/983/2099/23586/7128/7157/6233/55593/84282/10318/7706/79155/79589/64127/7189/7311/387/56957/10392/57506/7316/7415/5728/78990 33 Influenza_A_virus R-HSA-195721 Signaling by WNT 192/4622 331/10654 3.983447211789359e-8 1.5091759355234482e-7 5.920342311631026e-8 2788/8454/27123/9070/5689/857/5579/5682/5331/1459/5526/1452/5578/1212/5929/5582/27327/1460/143471/5705/6657/8452/5530/55366/5709/9978/5695/1457/4609/5881/5711/1387/5683/324/5699/8312/2782/5702/192669/57216/1855/163/5518/4343/5593/25776/3845/6659/80351/5696/5691/4920/7314/5879/5515/2787/5718/8945/161/79971/51701/5700/122706/5707/1856/1454/8322/23198/10681/9101/8395/7534/5528/89780/7477/2792/9861/81847/5519/2932/9580/5698/5880/5692/5713/2785/2783/2784/5710/5719/6233/7474/1857/7514/4040/1213/3710/1211/7855/331/8607/1175/26523/801/2791/7976/4221/123169/1173/7090/6597/864/4772/4041/409/79577/5706/160/23401/8658/5714/6934/10524/5688/5687/607/23236/5708/51339/5529/7088/2786/208/57680/5704/7311/387/5694/5516/57154/27161/815/5684/8295/5720/54331/7015/6885/1487/1499/5525/59345/139285/207/5690/57690/5717/9491/6500/51764/94235/3708/5330/10197/192670/64750/7316/10213/55970/54361/5216/5715/5701/2793/1455/5685/5686/2033/54894/5534/3065/23112/23513/5527/1488/5716/23072/9736/5693/5721/6259/2790 192 Influenza_A_virus R-HSA-8878171 Transcriptional regulation by RUNX1 145/4622 239/10654 4.14777847937271e-8 1.5671876524764997e-7 6.147916323622138e-8 1912/9070/5689/1437/5579/5682/1459/6045/9021/5929/27327/80012/1460/143471/5705/5709/5695/28996/1457/1911/6603/10413/5711/1387/3558/5683/10138/57332/5699/8312/5702/192669/83737/5371/57492/4343/5696/5691/7314/55170/5718/84661/25/4773/196528/5700/122706/5707/23198/86/100506658/7082/23309/6714/2099/9861/8850/84733/5588/8289/5698/5692/5713/6602/595/5710/3458/1998/896/5719/6233/26523/5781/1493/23429/55193/6015/55904/3562/6597/6929/8535/3674/7122/6938/5706/6599/200845/4331/2623/5714/5688/5687/5708/4602/5704/7311/7161/860/58508/25942/648/5694/23466/4297/27161/894/5684/5720/902/11091/640/5690/2625/57690/5717/9491/6598/10197/192670/5196/7316/10213/10398/5715/5701/5685/5686/2033/1021/84333/6605/50943/3065/861/23112/5716/9739/3276/3977/3559/7057/1022/5693/5721 145 Influenza_A_virus R-HSA-177929 Signaling by EGFR 40/4622 49/10654 4.2758208516352176e-8 1.611212277785993e-7 6.320620410560217e-8 5295/4893/5335/6456/30011/2885/8874/3845/3265/5829/7314/1839/5290/8027/2060/2069/102/6714/9146/6455/1445/6233/29924/5781/6464/5782/998/6654/7311/1956/2549/685/26018/58513/7316/1950/867/5774/10254/6457 40 Influenza_A_virus R-HSA-199992 trans-Golgi Network Vesicle Budding 54/4622 72/10654 4.622103778562834e-8 1.7370164200082911e-7 6.814137149494161e-8 27131/8773/8906/162/1176/27243/5286/1212/1174/1785/8546/7037/3482/408/6456/3312/26258/25977/10618/6643/55330/8301/9146/8729/4074/2495/388552/6844/1213/2580/1211/23431/8907/351/84062/9685/9179/9026/8775/9829/8905/51429/8673/2512/164/1777/6272/9698/5878/81567/10717/6845/375/4952 54 Influenza_A_virus R-HSA-2132295 MHC class II antigen presentation 83/4622 123/10654 5.135614724058142e-8 1.9248228912153573e-7 7.550882661871856e-8 162/51807/10484/1174/347688/1785/10381/1780/3115/1509/8655/84516/832/3113/10112/7846/5476/3117/9632/6456/11004/163/1759/3127/81930/51164/161/79861/3126/22872/3796/10437/10376/10540/1213/1211/6396/1175/7879/140735/8907/1508/3831/3120/1173/84617/11258/6712/1783/10382/10802/93661/821/55860/830/3123/7277/160/10671/3122/1639/26052/1062/347733/51143/9871/10383/84790/84643/8905/3125/7280/829/1778/114876/164/3119/1781/5641/10121/3799/375/10427 83 Influenza_A_virus R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 20/4622 20/10654 5.447744667669052e-8 2.0094847085491649e-7 7.883002282615127e-8 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Influenza_A_virus R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 20/4622 20/10654 5.447744667669052e-8 2.0094847085491649e-7 7.883002282615127e-8 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Influenza_A_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 20/4622 20/10654 5.447744667669052e-8 2.0094847085491649e-7 7.883002282615127e-8 7321/7334/3551/7314/11035/8737/8517/7323/6233/387522/330/7098/7189/7311/1147/7316/7335/7322/329/148022 20 Influenza_A_virus R-HSA-418217 G beta:gamma signalling through PLC beta 20/4622 20/10654 5.447744667669052e-8 2.0094847085491649e-7 7.883002282615127e-8 2788/5331/2782/2787/10681/2792/2785/2783/2784/2791/23236/2786/54331/59345/51764/94235/5330/55970/2793/2790 20 Influenza_A_virus R-HSA-5213460 RIPK1-mediated regulated necrosis 20/4622 20/10654 5.447744667669052e-8 2.0094847085491649e-7 7.883002282615127e-8 356/7314/11035/8737/841/8797/6233/8772/331/8717/8743/330/8837/197259/7311/8795/7186/355/7316/329 20 Influenza_A_virus R-HSA-5218859 Regulated Necrosis 20/4622 20/10654 5.447744667669052e-8 2.0094847085491649e-7 7.883002282615127e-8 356/7314/11035/8737/841/8797/6233/8772/331/8717/8743/330/8837/197259/7311/8795/7186/355/7316/329 20 Influenza_A_virus R-HSA-5628897 TP53 Regulates Metabolic Genes 62/4622 86/10654 5.936622342656054e-8 2.1817390593081505e-7 8.558738422555127e-8 5563/7531/10971/9997/27327/7295/7533/2810/53632/7001/6341/192669/2475/51204/4343/7296/9377/2936/51422/7249/27244/7534/2821/10000/2877/54541/7157/1337/50484/9167/26523/2744/57521/83667/7532/64223/5571/10128/6009/8626/208/5562/1340/4697/5564/5565/7248/7529/27161/27165/207/57690/192670/2539/54205/143686/5728/23112/10542/6834/1327/5052 62 Influenza_A_virus R-HSA-5654733 Negative regulation of FGFR4 signaling 28/4622 31/10654 5.945941213135946e-8 2.1817390593081505e-7 8.558738422555127e-8 8569/9965/2264/2885/5518/7314/5515/8823/5594/8074/2249/6714/2247/6233/2246/2251/5781/673/7311/5595/5516/8817/2254/7316/152831/26281/10818/867 28 Influenza_A_virus R-HSA-203927 MicroRNA (miRNA) biogenesis 23/4622 24/10654 6.201354036311436e-8 2.2576804538446322e-7 8.856648719622419e-8 5431/5435/5433/5439/192669/29102/5438/54487/57510/8575/26523/23405/5434/5436/5901/5432/27161/6895/5440/5430/5441/192670/5437 23 Influenza_A_virus R-HSA-5260271 Diseases of Immune System 23/4622 24/10654 6.201354036311436e-8 2.2576804538446322e-7 8.856648719622419e-8 4790/10333/4792/929/51135/7187/3551/8517/5970/7096/4791/81793/7098/695/81622/23643/1147/7099/4615/7100/114609/7097/148022 23 Influenza_A_virus R-HSA-5602358 Diseases associated with the TLR signaling cascade 23/4622 24/10654 6.201354036311436e-8 2.2576804538446322e-7 8.856648719622419e-8 4790/10333/4792/929/51135/7187/3551/8517/5970/7096/4791/81793/7098/695/81622/23643/1147/7099/4615/7100/114609/7097/148022 23 Influenza_A_virus R-HSA-1268020 Mitochondrial protein import 49/4622 64/10654 6.292680813355537e-8 2.2849786433950758e-7 8.963736715675284e-8 26519/131118/26520/3313/10440/50/25813/9512/80273/3421/131474/90639/134266/54927/3329/100287932/10469/8604/1431/9804/10245/7416/4714/293/1678/150274/4580/29090/10651/29928/10063/56942/10452/51025/400916/10165/56993/26521/100272147/26517/6901/92609/617/54543/1537/388753/2671/26515/291 49 Influenza_A_virus R-HSA-5675221 Negative regulation of MAPK pathway 34/4622 40/10654 6.419977190738134e-8 2.325162723484951e-7 9.121374737863562e-8 4893/1844/5526/5605/5037/5894/5518/4140/3845/3265/7314/5515/8844/1849/5594/5528/5519/80824/6233/1843/369/1846/673/8315/5529/7311/5536/7529/5595/5516/5604/5525/7316/5527 34 Influenza_A_virus R-HSA-187687 Signalling to ERKs 30/4622 34/10654 6.648318959643874e-8 2.3954510065933337e-7 9.397108458964891e-8 4893/5605/5898/1432/5603/2885/3845/3265/1399/5899/5594/9261/6714/4914/5600/6300/6464/673/7867/2889/6654/5900/7529/5595/5604/57498/10818/4803/1398/5906 30 Influenza_A_virus R-HSA-5654727 Negative regulation of FGFR2 signaling 30/4622 34/10654 6.648318959643874e-8 2.3954510065933337e-7 9.397108458964891e-8 8569/2885/5518/2252/7314/5515/8823/5594/8074/2249/6714/2248/2247/6233/2246/2251/5781/673/2263/7311/5595/5516/8817/2254/7316/26281/10818/867/2255/27006 30 Influenza_A_virus R-HSA-5689603 UCH proteinases 71/4622 102/10654 6.900667711542547e-8 2.479982894790869e-7 9.728718381040906e-8 5689/221937/5682/4738/10445/143471/5705/5709/5695/11047/5711/7347/5683/5699/5702/7040/7345/3054/5696/5691/7314/5718/3607/5700/122706/5707/83444/23198/86/4092/9861/29844/7046/5698/5692/5713/5710/8473/9958/5719/6233/8607/5706/580/5714/5688/5687/5708/5704/7048/7311/60/5694/7528/5684/5720/5690/5717/9491/10197/7316/10213/55252/5715/5701/4798/5685/5686/5716/5693/5721 71 Influenza_A_virus R-HSA-8939211 ESR-mediated signaling 136/4622 223/10654 6.971844410137718e-8 2.4991380731724437e-7 9.803862179977737e-8 5295/2788/3725/4893/857/2770/27327/10274/5431/5435/5433/1509/5469/1105/4609/1387/8312/2782/5439/192669/10499/1386/4343/3845/3265/8877/2773/2787/6387/1839/5290/5594/2069/10681/5481/5438/4313/1655/6667/2792/6714/2099/8850/10000/2785/595/2783/2784/2771/7514/1025/2353/26523/801/2791/5170/2963/3838/5434/5590/6464/7090/5241/5747/5436/1903/3315/4318/200845/5885/2962/8503/10524/8243/4602/2786/208/3326/23030/6908/1956/5536/3169/858/23189/5432/3480/10728/5595/7528/27161/596/5440/685/54331/2309/9687/59345/8204/5430/207/5451/2625/57690/1027/51764/94235/5441/10735/192670/2100/1950/55970/4314/346562/2289/7391/5437/2793/3320/2033/4846/9126/3065/2066/861/23028/23112/10498/1385/5296/3276/8202/8648/2288/2790 136 Influenza_A_virus R-HSA-432722 Golgi Associated Vesicle Biogenesis 44/4622 56/10654 7.743540703335397e-8 2.7686623793511217e-7 1.0861178372426281e-7 27131/162/1176/5286/1174/1785/8546/7037/3482/408/6456/3312/26258/25977/10618/6643/55330/8301/2495/388552/6844/1213/2580/1211/23431/8907/84062/9685/9026/8775/9829/8905/51429/8673/2512/164/6272/9698/5878/81567/10717/6845/375/4952 44 Influenza_A_virus R-HSA-5654716 Downstream signaling of activated FGFR4 25/4622 27/10654 9.898479240966637e-8 3.530120912977387e-7 1.3848302053017235e-7 5295/4893/5335/9965/2264/2885/3845/3265/5290/8823/8074/2249/2247/2246/2251/5781/6464/6654/2549/8817/10817/2254/152831/26281/10818 25 Influenza_A_virus R-HSA-167172 Transcription of the HIV genome 54/4622 73/10654 1.0274030272568452e-7 3.654731379402213e-7 1.4337136124302032e-7 6884/6875/6874/5431/5435/5433/8732/2965/5439/6873/6881/51616/11198/51497/2959/5438/83860/2068/1025/6883/6829/25920/2963/5434/5436/6878/4331/8148/2962/54457/8812/905/2071/6880/6908/6882/2961/5432/22916/6877/5440/902/5430/6749/5441/4686/6872/6879/9150/5437/2968/138474/1022/8178 54 Influenza_A_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 48/4622 63/10654 1.1219604960811437e-7 3.9809664302574593e-7 1.5616922748016988e-7 55718/4790/5435/4792/3428/1387/84265/22954/1660/3551/7314/11035/8737/29110/81844/8517/6778/51428/5970/3661/6233/661/4791/9533/3665/5434/23220/7098/9208/5591/7311/81030/2547/1147/170506/5440/6737/1499/7520/147945/5441/51082/4615/7316/4793/5437/2033/148022 48 Influenza_A_virus R-HSA-5654736 Signaling by FGFR1 40/4622 50/10654 1.2407943180402568e-7 4.3663182673422787e-7 1.712861845708401e-7 5295/4893/5335/8569/2885/5518/3845/3265/23769/7314/5515/5290/5594/8074/2260/2249/6714/2248/2247/6233/2246/2251/5781/6464/673/6654/7311/2549/5595/5516/8817/10817/2254/7316/26281/10818/867/2255/27006/161742 40 Influenza_A_virus R-HSA-114452 Activation of BH3-only proteins 27/4622 30/10654 1.2452979297680237e-7 4.3663182673422787e-7 1.712861845708401e-7 7531/10971/7533/2810/1869/8655/7159/637/23368/7027/7534/10000/7157/140735/572/7532/5366/8626/208/7161/7529/27113/596/10018/207/5534/5599 27 Influenza_A_virus R-HSA-5654696 Downstream signaling of activated FGFR2 27/4622 30/10654 1.2452979297680237e-7 4.3663182673422787e-7 1.712861845708401e-7 5295/4893/5335/2885/2252/3845/3265/5290/8823/8074/2249/2248/2247/2246/2251/5781/6464/2263/6654/2549/8817/10817/2254/26281/10818/2255/27006 27 Influenza_A_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 19/4622 19/10654 1.2586740069663364e-7 4.3663182673422787e-7 1.712861845708401e-7 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Influenza_A_virus R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 19/4622 19/10654 1.2586740069663364e-7 4.3663182673422787e-7 1.712861845708401e-7 11065/7321/8697/51529/29945/51434/29882/996/51433/119504/7324/64682/246184/8881/10393/51343/25906/991/8556 19 Influenza_A_virus R-HSA-176412 Phosphorylation of the APC/C 19/4622 19/10654 1.2586740069663364e-7 4.3663182673422787e-7 1.712861845708401e-7 11065/7321/8697/51529/29945/51434/29882/996/983/51433/119504/7324/64682/246184/8881/891/10393/25906/5347 19 Influenza_A_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 19/4622 19/10654 1.2586740069663364e-7 4.3663182673422787e-7 1.712861845708401e-7 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Influenza_A_virus R-HSA-77595 Processing of Intronless Pre-mRNAs 19/4622 19/10654 1.2586740069663364e-7 4.3663182673422787e-7 1.712861845708401e-7 51585/81608/1477/53981/11051/8106/1478/23283/10914/10898/51692/22916/1479/79869/29894/4686/8189/10978/55339 19 Influenza_A_virus R-HSA-8851708 Signaling by FGFR2 IIIa TM 19/4622 19/10654 1.2586740069663364e-7 4.3663182673422787e-7 1.712861845708401e-7 5431/5435/5433/5439/5438/2247/2246/2963/5434/5436/2263/2962/5432/22916/5440/5430/5441/4686/5437 19 Influenza_A_virus R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 33/4622 39/10654 1.267559358184977e-7 4.386257383026233e-7 1.7206837561604303e-7 9134/10528/10576/10574/6468/10564/54461/10693/8877/10575/898/10517/26985/26190/10238/7157/83752/26224/2629/8237/63971/6774/26272/26270/55135/22948/10694/8841/22803/7203/908/6950/55294 33 Influenza_A_virus R-HSA-180910 Vpr-mediated nuclear import of PICs 29/4622 33/10654 1.3611758398441047e-7 4.6870044928622127e-7 1.838663760847235e-7 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/3159/79023/23636/53371/9688/8480 29 Influenza_A_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 29/4622 33/10654 1.3611758398441047e-7 4.6870044928622127e-7 1.838663760847235e-7 4790/4792/3654/7334/3551/7314/257397/8767/23118/8517/5970/10454/6233/4791/351/387522/64127/3656/7189/7311/1147/6885/10392/7316/7335/4793/3146/6288/6285 29 Influenza_A_virus R-HSA-112040 G-protein mediated events 43/4622 55/10654 1.4160467318997468e-007 4.863963958712152e-7 1.908083143203849e-7 5331/2770/817/5578/5582/107/2774/814/2773/818/5567/5594/112/5573/111/5613/2771/5332/5580/3710/196883/115/801/3838/113/10645/5566/84254/23236/816/5577/109/815/5321/5575/114/3708/5330/108/10768/346562/5576/1385 43 Influenza_A_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 38/4622 47/10654 1.5335517051340882e-7 5.20365360140159e-7 2.041339903870363e-7 8454/79718/892/3091/9978/9759/9612/4609/22938/1387/6907/9794/7314/79885/2648/9734/55869/51564/3280/10013/8850/3066/6233/7090/1024/10014/7088/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 38 Influenza_A_virus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 38/4622 47/10654 1.5335517051340882e-7 5.20365360140159e-7 2.041339903870363e-7 4893/71/817/5908/5605/5037/3717/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/369/801/283455/3674/409/673/8315/816/60/7529/5595/815/5604/5906/5245 38 Influenza_A_virus R-HSA-6802949 Signaling by RAS mutants 38/4622 47/10654 1.5335517051340882e-7 5.20365360140159e-7 2.041339903870363e-7 4893/71/817/5908/5605/5037/3717/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/369/801/283455/3674/409/673/8315/816/60/7529/5595/815/5604/5906/5245 38 Influenza_A_virus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 38/4622 47/10654 1.5335517051340882e-7 5.20365360140159e-7 2.041339903870363e-7 4893/71/817/5908/5605/5037/3717/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/369/801/283455/3674/409/673/8315/816/60/7529/5595/815/5604/5906/5245 38 Influenza_A_virus R-HSA-9649948 Signaling downstream of RAS mutants 38/4622 47/10654 1.5335517051340882e-7 5.20365360140159e-7 2.041339903870363e-7 4893/71/817/5908/5605/5037/3717/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/369/801/283455/3674/409/673/8315/816/60/7529/5595/815/5604/5906/5245 38 Influenza_A_virus R-HSA-5619084 ABC transporter disorders 56/4622 77/10654 1.589205414019578e-7 5.379441086681282e-7 2.110299530277049e-7 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/5696/5691/7314/5718/5700/122706/5707/79139/23198/9861/5698/215/5692/5713/5710/5719/10613/6233/5706/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/1244/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 56 Influenza_A_virus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 36/4622 44/10654 1.8559909407080387e-7 6.26733172731845e-7 2.458609916371442e-7 892/7321/8239/9612/4609/4089/22938/23327/4088/1030/7314/5054/7027/6497/51592/7323/6667/4092/6233/1025/4221/1024/60436/8812/1874/142/905/4087/7311/64750/54778/7316/9611/5933/3065/25937 36 Influenza_A_virus R-HSA-6802952 Signaling by BRAF and RAF fusions 50/4622 67/10654 1.9146560890619233e-7 6.449853524117033e-7 2.530211344074222e-7 4893/71/817/5908/8546/5605/5037/3717/3690/408/5894/8826/4140/3845/3265/818/8805/55750/8844/7094/5594/7414/10533/23164/57085/6714/9061/2335/1445/369/801/57670/283455/3674/409/673/816/56829/60/7529/5595/4000/27044/815/22906/5604/10018/10142/5906/9715 50 Influenza_A_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 24/4622 26/10654 2.12347287037716e-7 7.118980989897529e-7 2.792703181790989e-7 9372/56937/23327/4088/5499/9110/7040/7314/4092/11171/7046/9958/6233/7514/5500/5501/23645/4087/7048/7311/57154/10273/64750/7316 24 Influenza_A_virus R-HSA-6803529 FGFR2 alternative splicing 24/4622 26/10654 2.12347287037716e-7 7.118980989897529e-7 2.792703181790989e-7 5431/5435/5433/5439/7072/7073/5438/3185/4670/5725/2963/5434/5436/2962/5432/22916/5440/23543/5430/3178/5441/4686/5437/3187 24 Influenza_A_virus R-HSA-5696400 Dual Incision in GG-NER 34/4622 41/10654 2.187504926202463e-7 7.316104992418764e-7 2.870032904939519e-7 5982/7507/9978/2965/2067/6117/10714/7314/6118/1643/5985/2068/5984/6233/5424/8451/54107/8450/5425/5111/6119/5427/1642/142/2071/51426/7311/5983/56655/57804/7316/5426/2968/5981 34 Influenza_A_virus R-HSA-112043 PLC beta mediated events 42/4622 54/10654 2.5770468206549484e-7 8.598356695168539e-7 3.3730470884593097e-7 5331/2770/817/5578/5582/107/814/2773/818/5567/5594/112/5573/111/5613/2771/5332/5580/3710/196883/115/801/3838/113/10645/5566/84254/23236/816/5577/109/815/5321/5575/114/3708/5330/108/10768/346562/5576/1385 42 Influenza_A_virus R-HSA-5675482 Regulation of necroptotic cell death 18/4622 18/10654 2.9077447302549805e-7 9.63276571776413e-7 3.7788351321098646e-7 356/7314/8737/841/8797/6233/8772/331/8717/8743/330/8837/7311/8795/7186/355/7316/329 18 Influenza_A_virus R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 18/4622 18/10654 2.9077447302549805e-7 9.63276571776413e-7 3.7788351321098646e-7 4893/5578/2885/6196/6197/3845/3265/1839/5594/5598/6195/2520/887/6654/1956/5595/4314/1385 18 Influenza_A_virus R-HSA-8964315 G beta:gamma signalling through BTK 18/4622 18/10654 2.9077447302549805e-7 9.63276571776413e-7 3.7788351321098646e-7 2788/2782/2787/10681/2792/2785/2783/2784/2791/695/2786/54331/59345/51764/94235/55970/2793/2790 18 Influenza_A_virus R-HSA-3928665 EPH-ephrin mediated repulsion of cells 40/4622 51/10654 3.339986761022216e-7 1.1038537805931579e-6 4.330305095166292e-7 71/2042/1947/1212/23385/2051/2050/2047/2534/1948/163/284656/1759/5879/161/2046/4313/2041/102/6714/5664/2043/7525/1942/7410/1213/1211/1175/5663/1173/7074/10451/4318/160/8218/4067/2048/60/1946/1969 40 Influenza_A_virus R-HSA-5696395 Formation of Incision Complex in GG-NER 35/4622 43/10654 3.5309700413471666e-7 1.1642207825007875e-6 4.5671186483164686e-7 6613/7507/9978/85015/2965/2067/6612/6117/7334/7314/6118/1643/2068/6233/5886/8451/8554/8450/4331/6119/1642/142/2071/1069/7329/7311/902/7336/54778/7316/7341/2968/5887/1022/7508 35 Influenza_A_virus R-HSA-2559583 Cellular Senescence 119/4622 195/10654 4.333256747404703e-7 1.4253865724404177e-6 5.59164523937548e-7 1912/3725/9134/2077/11065/4790/7321/6045/8697/27327/80012/7295/5925/472/79813/3576/2114/1869/1911/4194/1031/5928/1432/4683/23512/57332/192669/8900/51529/29945/8091/51434/1030/6196/4343/6197/29882/4217/54386/3569/7314/996/7014/5601/5606/7027/2146/5594/898/890/5970/9261/6667/51433/5598/84733/119504/6195/7157/7324/64682/6233/2353/8726/5600/26523/5608/6015/1019/9448/246184/1029/8535/5931/7013/1051/50488/8881/6774/7867/3552/10524/5602/10393/51343/7311/25906/3397/57634/648/23466/3456/2113/6416/23523/5595/1017/25913/3159/7290/10111/57690/1027/192670/8550/29855/7316/1026/1871/65057/1021/25842/23135/23112/5609/5599/10919/4193/23043 119 Influenza_A_virus R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 23/4622 25/10654 4.541690729591198e-7 1.4869516721237692e-6 5.83315880714166e-7 5982/6117/10714/7314/6118/5985/5984/6233/5424/7515/54107/5425/5111/6119/5427/51426/7311/5983/56655/57804/7316/5426/5981 23 Influenza_A_virus R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 23/4622 25/10654 4.541690729591198e-7 1.4869516721237692e-6 5.83315880714166e-7 51400/5520/8900/5518/7465/5515/993/890/983/5519/7514/2305/9133/891/4331/5347/5516/1017/994/902/9088/995/1022 23 Influenza_A_virus R-HSA-1236394 Signaling by ERBB4 44/4622 58/10654 4.7305600202374226e-7 1.5451689038065225e-6 6.061539032325867e-7 5295/4893/51741/23385/6776/4734/10413/145957/83737/9542/2885/3845/3265/7314/6387/1839/5290/2065/2069/23118/348/11059/6714/2099/5664/2567/3925/6233/5663/6464/5241/3084/6654/10718/7311/1956/685/7316/1950/9611/2066/6285/1742/11033 44 Influenza_A_virus R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 25/4622 28/10654 5.404232748316028e-7 1.7570040423594902e-6 6.892546540691924e-7 2788/2770/2782/2787/10681/112/111/2792/2785/2783/2784/2771/2791/150/775/2786/54331/59345/776/51764/94235/55970/152/2793/2790 25 Influenza_A_virus R-HSA-75067 Processing of Capped Intronless Pre-mRNA 25/4622 28/10654 5.404232748316028e-7 1.7570040423594902e-6 6.892546540691924e-7 51585/81608/1477/53981/134353/11051/8106/1478/23283/6636/10914/6635/6637/10898/51692/22916/1479/79869/29894/4686/8189/10978/6634/55339/6628 25 Influenza_A_virus R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 27/4622 31/10654 5.637548636835432e-7 1.82016004487204e-6 7.140301056986168e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/79023/23636/53371/9688/8480 27 Influenza_A_virus R-HSA-1839124 FGFR1 mutant receptor activation 27/4622 31/10654 5.637548636835432e-7 1.82016004487204e-6 7.140301056986168e-7 5295/11052/9530/613/6776/11064/2885/9846/7750/8805/26127/5290/8074/2260/2249/399687/2247/2246/2251/6777/1523/9208/6774/6772/11160/2254/26281 27 Influenza_A_virus R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 27/4622 31/10654 5.637548636835432e-7 1.82016004487204e-6 7.140301056986168e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/79023/23636/53371/9688/8480 27 Influenza_A_virus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 48/4622 65/10654 5.761150959698094e-7 1.8557808851746394e-6 7.280037957804286e-7 3725/4436/472/5431/5435/5433/2965/5439/672/1386/11198/51497/2176/5438/1643/9656/2068/7157/1025/2353/6829/25920/2963/5434/5436/4292/4331/2962/8812/905/1111/2071/55215/5432/5440/8621/902/5430/6749/545/5441/5395/9150/5437/51755/2968/1022/8178 48 Influenza_A_virus R-HSA-1489509 DAG and IP3 signaling 34/4622 42/10654 6.684100114190723e-7 2.1174979973254477e-6 8.306727329316756e-7 5335/817/5578/5582/107/814/818/5567/112/5573/111/5613/5580/3710/196883/115/801/3838/113/10645/5566/84254/816/5577/109/815/5575/114/3708/108/10768/5576/1385/5581 34 Influenza_A_virus R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 34/4622 42/10654 6.684100114190723e-7 2.1174979973254477e-6 8.306727329316756e-7 2788/2740/2782/8826/2787/5567/10681/112/5573/111/2792/2785/2783/2784/3710/2791/5566/2641/2786/5577/54331/5575/59345/51764/94235/114/3708/3790/55970/2778/2793/5576/5906/2790 34 Influenza_A_virus R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 17/4622 17/10654 6.716543039244788e-7 2.1174979973254477e-6 8.306727329316756e-7 356/100302736/929/8737/841/8797/8772/8717/8743/8837/8795/23643/7186/355/7099/353376/148022 17 Influenza_A_virus R-HSA-432142 Platelet sensitization by LDL 17/4622 17/10654 6.716543039244788e-7 2.1174979973254477e-6 8.306727329316756e-7 5777/5526/5175/2268/1432/5518/5515/5528/5519/5781/338/5529/5516/5321/5525/5527/7804 17 Influenza_A_virus R-HSA-450385 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA 17/4622 17/10654 6.716543039244788e-7 2.1174979973254477e-6 8.306727329316756e-7 5393/23404/11340/9261/23016/118460/677/51010/56915/167227/7529/22894/207/55802/51013/54464/54512 17 Influenza_A_virus R-HSA-450513 Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA 17/4622 17/10654 6.716543039244788e-7 2.1174979973254477e-6 8.306727329316756e-7 5393/23404/11340/9261/23016/118460/3842/7538/51010/56915/167227/7529/22894/55802/51013/54464/54512 17 Influenza_A_virus R-HSA-450604 KSRP (KHSRP) binds and destabilizes mRNA 17/4622 17/10654 6.716543039244788e-7 2.1174979973254477e-6 8.306727329316756e-7 5393/23404/1432/11340/7534/5600/8570/23016/118460/5073/51010/56915/167227/22894/207/51013/54512 17 Influenza_A_virus R-HSA-500657 Presynaptic function of Kainate receptors 20/4622 21/10654 6.725100935711722e-7 2.1174979973254477e-6 8.306727329316756e-7 2788/5331/2782/2787/10681/2792/2785/2783/2784/2791/23236/2786/54331/59345/51764/94235/5330/55970/2793/2790 20 Influenza_A_virus R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 20/4622 21/10654 6.725100935711722e-7 2.1174979973254477e-6 8.306727329316756e-7 25904/55571/55835/57472/85456/29883/1263/7832/10769/7157/5325/4869/4850/246175/4848/23019/4849/9337/28984/995 20 Influenza_A_virus R-HSA-6807004 Negative regulation of MET activity 20/4622 21/10654 6.725100935711722e-7 2.1174979973254477e-6 8.306727329316756e-7 5770/3082/6456/30011/2885/7314/8027/2060/9101/9146/6455/6233/4233/5795/7311/26018/7316/867/10254/6457 20 Influenza_A_virus R-HSA-73762 RNA Polymerase I Transcription Initiation 37/4622 47/10654 7.880074547153069e-7 2.4706351204294652e-6 9.692048021562768e-7 2074/9112/5435/5928/2965/1107/2648/8850/57459/2068/3066/9533/5434/9015/9219/5931/4331/9013/1108/54815/2071/57504/6908/53615/5440/902/9014/25885/5441/51082/7343/5437/3065/2968/84172/1022/10919 37 Influenza_A_virus R-HSA-4086398 Ca2+ pathway 46/4622 62/10654 7.899670234849577e-7 2.4706351204294652e-6 9.692048021562768e-7 2788/5331/5578/27327/5530/2782/192669/4343/5593/3845/2787/51701/8322/10681/2792/2785/2783/2784/7474/3710/7855/26523/801/2791/7976/4772/6934/23236/2786/27161/815/54331/6885/1499/59345/57690/51764/94235/3708/5330/192670/55970/2793/5534/23112/2790 46 Influenza_A_virus R-HSA-8986944 Transcriptional Regulation by MECP2 46/4622 62/10654 7.899670234849577e-7 2.4706351204294652e-6 9.692048021562768e-7 627/2290/79718/5770/817/9212/27327/6657/28996/9612/4988/6907/192669/3654/4343/6750/814/818/6446/54487/3066/26523/801/2904/3930/4233/6515/5566/816/25942/27161/815/8841/5468/4986/57690/192670/9611/2874/2289/5775/3064/5728/3065/23112/1385 46 Influenza_A_virus R-HSA-6807878 COPI-mediated anterograde transport 68/4622 101/10654 9.322137926080299e-7 2.9090064331830933e-6 1.141173369240563e-6 6811/6711/11014/51807/347688/5861/10381/1780/9570/8655/84516/832/55738/7846/100302736/3630/6709/54732/51164/79861/2801/377/1315/8615/11316/8729/10376/1314/10540/378/26286/26958/140735/84364/22820/84617/11258/6712/1783/10382/93661/55860/830/7277/10671/1639/10282/8775/347733/51143/10383/84790/7280/829/1778/51014/1604/1781/10121/10972/6708/9276/287/375/84342/64689/22818/372 68 Influenza_A_virus R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress 24/4622 27/10654 1.119247244062112e-6 3.477128104886294e-6 1.3640416705411939e-6 5393/23404/3576/4801/6347/11340/468/8570/23016/118460/5073/1051/4800/22926/51010/56915/167227/22894/440/9709/4802/51013/467/54512 24 Influenza_A_virus R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 24/4622 27/10654 1.119247244062112e-6 3.477128104886294e-6 1.3640416705411939e-6 356/836/100302736/929/26060/219699/1612/8737/841/8797/1613/8772/8717/8743/8837/8795/23643/7186/842/355/7099/23604/353376/148022 24 Influenza_A_virus R-HSA-180786 Extension of Telomeres 26/4622 30/10654 1.139831610032591e-6 3.5332252568194286e-6 1.3860480075317539e-6 1763/5982/5422/6117/10714/6118/5985/5984/23649/8607/5424/55651/54107/5425/5111/6119/5427/55135/5983/56655/7015/57804/10856/5426/1736/5981 26 Influenza_A_virus R-HSA-112382 Formation of RNA Pol II elongation complex 45/4622 61/10654 1.3661830358242521e-6 4.216167514530474e-6 1.6539592463446856e-6 5431/5435/5433/2965/5439/11198/51497/4300/80349/5438/2068/1025/55677/6829/123169/25920/85403/2963/5434/5436/9646/79577/4331/2962/4298/8812/905/2071/27125/5432/22916/55840/5440/902/6830/5430/6749/5441/4686/9150/54623/5437/2968/1022/8178 45 Influenza_A_virus R-HSA-75955 RNA Polymerase II Transcription Elongation 45/4622 61/10654 1.3661830358242521e-6 4.216167514530474e-6 1.6539592463446856e-6 5431/5435/5433/2965/5439/11198/51497/4300/80349/5438/2068/1025/55677/6829/123169/25920/85403/2963/5434/5436/9646/79577/4331/2962/4298/8812/905/2071/27125/5432/22916/55840/5440/902/6830/5430/6749/5441/4686/9150/54623/5437/2968/1022/8178 45 Influenza_A_virus R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 19/4622 20/10654 1.4822765270755493e-6 4.544347773797408e-6 1.7827009940128377e-6 472/1387/51499/7159/637/27166/23368/7157/63970/55240/5366/84883/147923/94241/8626/7161/665/27113/581 19 Influenza_A_virus R-HSA-8876384 Listeria monocytogenes entry into host cells 19/4622 20/10654 1.4822765270755493e-6 4.544347773797408e-6 1.7827009940128377e-6 6456/30011/2885/7314/8027/2060/1500/6714/999/9146/6455/6233/4233/7311/1499/7316/867/10254/6457 19 Influenza_A_virus R-HSA-8964616 G beta:gamma signalling through CDC42 19/4622 20/10654 1.4822765270755493e-6 4.544347773797408e-6 1.7827009940128377e-6 2788/2782/2787/10681/2792/2785/2783/2784/2791/998/2786/5058/54331/59345/51764/94235/55970/2793/2790 19 Influenza_A_virus R-HSA-111996 Ca-dependent events 31/4622 38/10654 1.543162855727549e-6 4.67380991165841e-6 1.833487662054086e-6 817/5578/5582/107/814/818/5567/5594/112/5573/111/5613/5580/196883/115/801/3838/113/10645/5566/84254/816/5577/109/815/5321/5575/114/108/5576/1385 31 Influenza_A_virus R-HSA-193639 p75NTR signals via NF-kB 16/4622 16/10654 1.5512502138837641e-6 4.67380991165841e-6 1.833487662054086e-6 4790/8878/4792/3654/3551/7314/8767/5970/6233/7189/7311/4804/5584/4615/7316/4803 16 Influenza_A_virus R-HSA-1963640 GRB2 events in ERBB2 signaling 16/4622 16/10654 1.5512502138837641e-6 4.67380991165841e-6 1.833487662054086e-6 4893/2064/145957/9542/2885/3845/3265/1839/2069/3084/6654/10718/1956/685/1950/2066 16 Influenza_A_virus R-HSA-1963642 PI3K events in ERBB2 signaling 16/4622 16/10654 1.5512502138837641e-6 4.67380991165841e-6 1.833487662054086e-6 5295/2064/145957/9542/2885/1839/5290/2065/2069/3084/10718/1956/2549/685/1950/2066 16 Influenza_A_virus R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 16/4622 16/10654 1.5512502138837641e-6 4.67380991165841e-6 1.833487662054086e-6 5295/5291/2534/2885/9846/5290/5170/6464/2205/2206/6850/4067/6654/7462/5296/2207 16 Influenza_A_virus R-HSA-399954 Sema3A PAK dependent Axon repulsion 16/4622 16/10654 1.5512502138837641e-6 4.67380991165841e-6 1.833487662054086e-6 5361/8829/2534/5362/5062/5879/1072/10371/55558/5063/3326/5058/3984/3320/91584/2242 16 Influenza_A_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 16/4622 16/10654 1.5512502138837641e-6 4.67380991165841e-6 1.833487662054086e-6 8454/4790/3551/7314/8945/1326/8517/6233/79155/7311/6416/1147/5604/6500/7316/23291 16 Influenza_A_virus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 16/4622 16/10654 1.5512502138837641e-6 4.67380991165841e-6 1.833487662054086e-6 100302736/929/7314/257397/23118/10454/6233/3656/7189/7311/23643/6885/7099/7316/353376/148022 16 Influenza_A_virus R-HSA-442755 Activation of NMDA receptors and postsynaptic events 63/4622 93/10654 1.6835524140628969e-6 5.061518870666516e-6 1.9855819077006663e-6 5563/4893/51807/817/347688/53632/10381/107/7846/1741/1739/6196/1740/8874/6197/3845/3265/814/5879/818/79861/5567/5594/51422/5573/6714/10376/6195/5613/801/57576/5170/84617/3838/2904/10382/7277/10645/55327/5566/84254/5571/27330/347733/3084/816/5577/5562/10383/84790/5564/5565/7280/5595/815/5575/114/5576/4137/2066/1742/88/1385 63 Influenza_A_virus R-HSA-114604 GPVI-mediated activation cascade 29/4622 35/10654 1.8388385153977226e-6 5.504702879070698e-6 2.1594384458970215e-6 5295/5777/5291/2534/51206/5879/5290/5336/146850/5880/5294/7410/7409/3932/5781/5170/5590/3937/10451/6850/8503/4067/998/387/27040/23533/391/5296/2207 29 Influenza_A_virus R-HSA-8953750 Transcriptional Regulation by E2F6 29/4622 35/10654 1.8388385153977226e-6 5.504702879070698e-6 2.1594384458970215e-6 6045/80012/79813/11335/1869/1911/5928/10138/23512/672/6241/5888/83746/7027/2146/8726/7703/317/23429/6015/84108/5931/1111/648/23468/8317/4149/5932/10919 29 Influenza_A_virus R-HSA-75893 TNF signaling 34/4622 43/10654 1.8595924833821778e-6 5.554936520872403e-6 2.1791445880389444e-6 7124/7375/9530/10616/1540/3551/7314/257397/81858/8737/55072/23118/841/8517/7128/10454/6233/8772/331/8717/330/27005/8567/7311/1147/7186/56957/6885/7316/7132/329/9099/55512/7185 34 Influenza_A_virus R-HSA-389948 PD-1 signaling 21/4622 23/10654 2.056939025630135e-6 6.1313448994262875e-6 2.4052636793924373e-6 5777/3115/3113/3117/3127/5133/3126/29126/1445/916/3932/5781/3120/3123/3122/920/3125/3119/919/915/917 21 Influenza_A_virus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 51/4622 72/10654 2.120010103128091e-6 6.305902391857598e-6 2.473740792227851e-6 8773/5563/71/7531/51807/10971/347688/7533/2810/53632/10381/60412/5898/7846/23433/5879/79861/51422/4644/7534/5872/4641/10376/11336/6844/9882/801/4218/84617/7532/10382/7277/5571/347733/208/5867/10383/60/84790/5564/5565/7280/7529/55770/6517/10890/4627/207/8766/149371/6814 51 Influenza_A_virus R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 25/4622 29/10654 2.2936726888776364e-6 6.779184818289505e-6 2.659404630922997e-6 5431/5435/5433/55124/84944/5439/11022/91646/5438/56165/54514/5434/5436/122402/143689/5432/5440/8468/5430/5441/5437/3320/54456/9271/136991 25 Influenza_A_virus R-HSA-5654732 Negative regulation of FGFR3 signaling 25/4622 29/10654 2.2936726888776364e-6 6.779184818289505e-6 2.659404630922997e-6 8569/2885/5518/7314/5515/8823/5594/8074/2249/6714/2247/6233/2246/5781/673/7311/5595/5516/8817/2254/7316/26281/10818/2261/867 25 Influenza_A_virus R-HSA-72086 mRNA Capping 25/4622 29/10654 2.2936726888776364e-6 6.779184818289505e-6 2.659404630922997e-6 5431/5435/5433/8732/2965/5439/5438/2068/6829/2963/5434/5436/4331/2962/2071/5432/22916/5440/902/5430/5441/4686/5437/2968/1022 25 Influenza_A_virus R-HSA-6807505 RNA polymerase II transcribes snRNA genes 52/4622 74/10654 2.4860098856805505e-6 7.332155738779346e-6 2.8763294480114743e-6 6884/51585/5431/5435/5433/5439/10302/65123/55197/2959/79871/5438/6667/29101/25896/23248/1025/6829/2963/5434/5436/26512/6878/58490/2962/51808/8812/129685/905/64859/6880/6908/80237/6619/6882/2961/5432/22916/6618/6877/5440/5430/5451/5441/84524/4686/5437/80789/51593/79035/1022/8178 52 Influenza_A_virus R-HSA-176187 Activation of ATR in response to replication stress 30/4622 37/10654 2.9282132626454355e-6 8.61819398142804e-6 3.3808290522731785e-6 5982/4174/84515/10926/84126/55388/6117/5001/6118/63967/993/5985/5984/5884/5810/4172/8318/4173/6119/3364/144715/1111/5983/4176/1017/5883/8317/545/4171/995 30 Influenza_A_virus R-HSA-202430 Translocation of ZAP-70 to Immunological synapse 18/4622 19/10654 3.2591017749450695e-6 9.531849961031815e-6 3.73924691642013e-6 3115/3113/3117/26191/3127/3126/916/3932/3120/3123/3122/920/7535/3125/3119/919/915/917 18 Influenza_A_virus R-HSA-392851 Prostacyclin signalling through prostacyclin receptor 18/4622 19/10654 3.2591017749450695e-6 9.531849961031815e-6 3.73924691642013e-6 2788/2782/2787/10681/2792/2785/2783/2784/2791/2786/54331/59345/51764/94235/55970/2778/2793/2790 18 Influenza_A_virus R-HSA-6804760 Regulation of TP53 Activity through Methylation 18/4622 19/10654 3.2591017749450695e-6 9.531849961031815e-6 3.73924691642013e-6 133383/11200/472/79813/4194/56950/7314/7157/6233/10419/26013/7311/7316/2033/91875/133746/10919/4193 18 Influenza_A_virus R-HSA-445717 Aquaporin-mediated transport 39/4622 52/10654 3.502492292880459e-6 1.0117341828820915e-5 3.968929367378735e-6 2788/360/107/554/2782/2787/5567/10681/112/5573/111/2792/2785/2783/2784/196883/115/2791/359/113/5566/2786/5577/109/54331/5575/59345/51764/94235/114/108/8766/55970/2778/2793/5576/4645/551/2790 39 Influenza_A_virus R-HSA-4551638 SUMOylation of chromatin organization proteins 50/4622 71/10654 3.504322051091405e-6 1.0117341828820915e-5 3.968929367378735e-6 1912/23165/6045/80012/348995/6613/57122/23511/9759/1911/23279/23225/23512/57332/1107/9972/6612/8021/55746/83746/10762/79902/9883/84733/3066/9063/6396/129401/7703/6015/8554/4928/5903/55706/7175/8535/4927/8086/7329/648/23468/81929/9631/79023/23636/53371/9688/7341/3065/8480 50 Influenza_A_virus R-HSA-70171 Glycolysis 50/4622 71/10654 3.504322051091405e-6 1.0117341828820915e-5 3.968929367378735e-6 23165/7167/348995/57122/3099/23511/23279/23225/9972/5518/8021/55746/5515/2597/5567/10762/5528/79902/5519/9883/226/2821/5208/6396/129401/4928/5903/55706/7175/4927/5566/2023/8086/5516/81929/9631/5315/79023/23636/5214/83440/53371/5230/3098/9688/5209/5224/5213/8480/5223 50 Influenza_A_virus R-HSA-430039 mRNA decay by 5' to 3' exoribonuclease 15/4622 15/10654 3.5823206046254315e-6 1.0117341828820915e-5 3.968929367378735e-6 80153/219988/51690/11157/23644/27258/57819/23658/167227/1656/27257/25804/55802/196513/54464 15 Influenza_A_virus R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 15/4622 15/10654 3.5823206046254315e-6 1.0117341828820915e-5 3.968929367378735e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Influenza_A_virus R-HSA-5099900 WNT5A-dependent internalization of FZD4 15/4622 15/10654 3.5823206046254315e-6 1.0117341828820915e-5 3.968929367378735e-6 5579/5578/1212/5582/163/161/1856/8322/7474/1213/1211/1175/1173/409/160 15 Influenza_A_virus R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 15/4622 15/10654 3.5823206046254315e-6 1.0117341828820915e-5 3.968929367378735e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Influenza_A_virus R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 15/4622 15/10654 3.5823206046254315e-6 1.0117341828820915e-5 3.968929367378735e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Influenza_A_virus R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 15/4622 15/10654 3.5823206046254315e-6 1.0117341828820915e-5 3.968929367378735e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Influenza_A_virus R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 15/4622 15/10654 3.5823206046254315e-6 1.0117341828820915e-5 3.968929367378735e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Influenza_A_virus R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 15/4622 15/10654 3.5823206046254315e-6 1.0117341828820915e-5 3.968929367378735e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/139285/5527 15 Influenza_A_virus R-HSA-5637810 Constitutive Signaling by EGFRvIII 15/4622 15/10654 3.5823206046254315e-6 1.0117341828820915e-5 3.968929367378735e-6 5295/4893/5335/2885/3845/3265/5290/6464/6654/1956/2549/11140/1950/867/3320 15 Influenza_A_virus R-HSA-5637812 Signaling by EGFRvIII in Cancer 15/4622 15/10654 3.5823206046254315e-6 1.0117341828820915e-5 3.968929367378735e-6 5295/4893/5335/2885/3845/3265/5290/6464/6654/1956/2549/11140/1950/867/3320 15 Influenza_A_virus R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 15/4622 15/10654 3.5823206046254315e-6 1.0117341828820915e-5 3.968929367378735e-6 6456/30011/2885/7314/8027/2060/9146/6455/6233/4233/7311/7316/867/10254/6457 15 Influenza_A_virus R-HSA-937039 IRAK1 recruits IKK complex 15/4622 15/10654 3.5823206046254315e-6 1.0117341828820915e-5 3.968929367378735e-6 3654/7334/3551/7314/8517/6233/387522/57162/7189/7311/1147/246330/7316/7335/57161 15 Influenza_A_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 15/4622 15/10654 3.5823206046254315e-6 1.0117341828820915e-5 3.968929367378735e-6 3654/51135/7334/7314/54106/6233/51311/3665/387522/7189/7311/51284/4615/7316/7335 15 Influenza_A_virus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 15/4622 15/10654 3.5823206046254315e-6 1.0117341828820915e-5 3.968929367378735e-6 3654/7334/3551/7314/8517/6233/387522/57162/7189/7311/1147/246330/7316/7335/57161 15 Influenza_A_virus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 26/4622 31/10654 4.13543069104768e-6 1.1655911504202936e-5 4.572494461026829e-6 3725/9252/1432/6196/5518/1386/6197/51231/5515/5601/1849/5594/5528/9261/5519/5598/6195/2353/5600/1846/5602/5595/5516/4205/1385/5599 26 Influenza_A_virus R-HSA-5654712 FRS-mediated FGFR4 signaling 20/4622 22/10654 4.353242378055005e-6 1.2245136508090336e-5 4.803641382964435e-6 4893/9965/2264/2885/3845/3265/8823/8074/2249/2247/2246/2251/5781/6654/8817/10817/2254/152831/26281/10818 20 Influenza_A_virus R-HSA-202040 G-protein activation 24/4622 28/10654 4.59219105944516e-6 1.2865497196601872e-5 5.047002514441364e-6 2788/2770/4988/2782/2773/2787/10681/5443/2792/2785/2783/2784/2771/2791/2786/54331/59345/51764/94235/5173/55970/346562/2793/2790 24 Influenza_A_virus R-HSA-350054 Notch-HLH transcription pathway 24/4622 28/10654 4.59219105944516e-6 1.2865497196601872e-5 5.047002514441364e-6 79718/9759/9612/22938/1387/6907/4853/9794/79885/2648/9734/55869/51564/10013/4854/8850/3066/10014/4855/4851/8841/9611/3065/3516 24 Influenza_A_virus R-HSA-1643713 Signaling by EGFR in Cancer 22/4622 25/10654 4.738042010556768e-6 1.3194786316251717e-5 5.17617925665774e-6 5295/4893/5335/2885/3845/3265/7314/1839/5290/2069/6233/6464/6654/7311/1956/2549/11140/685/7316/1950/867/3320 22 Influenza_A_virus R-HSA-5654700 FRS-mediated FGFR2 signaling 22/4622 25/10654 4.738042010556768e-6 1.3194786316251717e-5 5.17617925665774e-6 4893/2885/2252/3845/3265/8823/8074/2249/2248/2247/2246/2251/5781/2263/6654/8817/10817/2254/26281/10818/2255/27006 22 Influenza_A_virus R-HSA-5654708 Downstream signaling of activated FGFR3 22/4622 25/10654 4.738042010556768e-6 1.3194786316251717e-5 5.17617925665774e-6 5295/4893/5335/2885/3845/3265/5290/8823/8074/2249/2247/2246/5781/6464/6654/2549/8817/10817/2254/26281/10818/2261 22 Influenza_A_virus R-HSA-111933 Calmodulin induced events 29/4622 36/10654 5.524128345570749e-6 1.5292537479421598e-5 5.999105509207631e-6 817/5578/5582/107/814/818/5567/112/5573/111/5613/5580/196883/115/801/3838/113/10645/5566/84254/816/5577/109/815/5575/114/108/5576/1385 29 Influenza_A_virus R-HSA-111997 CaM pathway 29/4622 36/10654 5.524128345570749e-6 1.5292537479421598e-5 5.999105509207631e-6 817/5578/5582/107/814/818/5567/112/5573/111/5613/5580/196883/115/801/3838/113/10645/5566/84254/816/5577/109/815/5575/114/108/5576/1385 29 Influenza_A_virus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 29/4622 36/10654 5.524128345570749e-6 1.5292537479421598e-5 5.999105509207631e-6 4893/71/5908/5605/5037/3690/408/5894/8826/4140/3845/3265/8844/7094/5594/7414/6714/2335/1445/369/283455/3674/409/673/60/7529/5595/5604/5906 29 Influenza_A_virus R-HSA-6806834 Signaling by MET 54/4622 79/10654 6.0770486051657445e-6 1.6789948517829467e-5 6.5865244919728575e-6 5295/4893/5770/5908/3082/1289/3688/3910/6456/30011/2885/3845/3265/1399/7314/5879/3918/5290/8027/3911/2060/284217/9101/6714/9146/6455/2335/64759/6233/5781/6464/85440/5747/382/3912/6774/4233/5795/2889/6654/5867/7311/2549/53916/26018/10048/7316/867/3914/1398/5906/23163/10254/6457 54 Influenza_A_virus R-HSA-113418 Formation of the Early Elongation Complex 27/4622 33/10654 6.785284978309697e-6 1.8563264970013614e-5 7.282178337005567e-6 5431/5435/5433/2965/5439/51497/5438/2068/6829/25920/2963/5434/5436/4331/2962/2071/5432/22916/5440/902/5430/5441/4686/9150/5437/2968/1022 27 Influenza_A_virus R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 27/4622 33/10654 6.785284978309697e-6 1.8563264970013614e-5 7.282178337005567e-6 5431/5435/5433/2965/5439/51497/5438/2068/6829/25920/2963/5434/5436/4331/2962/2071/5432/22916/5440/902/5430/5441/4686/9150/5437/2968/1022 27 Influenza_A_virus R-HSA-2871809 FCERI mediated Ca+2 mobilization 27/4622 33/10654 6.785284978309697e-6 1.8563264970013614e-5 7.282178337005567e-6 5335/5530/2885/7294/4773/5336/7410/7409/3702/3710/801/6464/2205/4772/3937/10451/2206/6850/4067/695/6654/9402/3708/10768/27040/5534/2207 27 Influenza_A_virus R-HSA-5357905 Regulation of TNFR1 signaling 27/4622 33/10654 6.785284978309697e-6 1.8563264970013614e-5 7.282178337005567e-6 7124/7375/10616/1540/3551/7314/81858/8737/55072/841/8517/7128/6233/331/8717/330/27005/8567/7311/1147/7186/56957/7316/7132/329/9099/7185 27 Influenza_A_virus R-HSA-5654726 Negative regulation of FGFR1 signaling 27/4622 33/10654 6.785284978309697e-6 1.8563264970013614e-5 7.282178337005567e-6 8569/2885/5518/7314/5515/5594/8074/2260/2249/6714/2248/2247/6233/2246/2251/5781/673/7311/5595/5516/2254/7316/26281/10818/867/2255/27006 27 Influenza_A_virus R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 17/4622 18/10654 7.146611429207113e-6 1.9437670774380438e-5 7.625198760223031e-6 5295/11052/613/6776/11064/2885/9846/7750/8805/26127/5290/399687/6777/1523/9208/6774/6772 17 Influenza_A_virus R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 17/4622 18/10654 7.146611429207113e-6 1.9437670774380438e-5 7.625198760223031e-6 2810/6790/1647/7027/5934/983/7157/891/5111/1874/25946/5933/2033/995/10498/581/3276 17 Influenza_A_virus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 17/4622 18/10654 7.146611429207113e-6 1.9437670774380438e-5 7.625198760223031e-6 100302736/929/7187/7314/29110/3661/6233/10010/5781/3665/7311/9641/23643/7099/7316/353376/148022 17 Influenza_A_virus R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 30/4622 38/10654 8.122152288587393e-6 2.181850102530218e-5 8.559174033719175e-6 1912/1459/6045/80012/1460/28996/1457/1911/6603/10138/57332/57492/196528/86/84733/8289/6602/23429/55193/6015/6597/8535/6599/648/23466/6598/2033/84333/6605/861 30 Influenza_A_virus R-HSA-1250347 SHC1 events in ERBB4 signaling 14/4622 14/10654 8.271677784985805e-6 2.181850102530218e-5 8.559174033719175e-6 4893/145957/9542/2885/3845/3265/1839/2069/6464/3084/6654/10718/685/2066 14 Influenza_A_virus R-HSA-169893 Prolonged ERK activation events 14/4622 14/10654 8.271677784985805e-6 2.181850102530218e-5 8.559174033719175e-6 5605/1399/5594/4914/673/2889/7529/5595/5604/57498/10818/4803/1398/5906 14 Influenza_A_virus R-HSA-170670 Adenylate cyclase inhibitory pathway 14/4622 14/10654 8.271677784985805e-6 2.181850102530218e-5 8.559174033719175e-6 2770/107/2774/2773/112/111/2771/196883/115/113/109/114/108/346562 14 Influenza_A_virus R-HSA-198323 AKT phosphorylates targets in the cytosol 14/4622 14/10654 8.271677784985805e-6 2.181850102530218e-5 8.559174033719175e-6 84335/7249/2932/10000/2931/23608/572/208/1147/842/207/1027/1026/4193 14 Influenza_A_virus R-HSA-3371568 Attenuation phase 14/4622 14/10654 8.271677784985805e-6 2.181850102530218e-5 8.559174033719175e-6 3305/1387/3306/3312/3303/3337/3297/3281/3326/3304/10728/3320/2033/2288 14 Influenza_A_virus R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 14/4622 14/10654 8.271677784985805e-6 2.181850102530218e-5 8.559174033719175e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Influenza_A_virus R-HSA-4839744 truncated APC mutants destabilize the destruction complex 14/4622 14/10654 8.271677784985805e-6 2.181850102530218e-5 8.559174033719175e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Influenza_A_virus R-HSA-4839748 AMER1 mutants destabilize the destruction complex 14/4622 14/10654 8.271677784985805e-6 2.181850102530218e-5 8.559174033719175e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Influenza_A_virus R-HSA-5467337 APC truncation mutants have impaired AXIN binding 14/4622 14/10654 8.271677784985805e-6 2.181850102530218e-5 8.559174033719175e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Influenza_A_virus R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 14/4622 14/10654 8.271677784985805e-6 2.181850102530218e-5 8.559174033719175e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Influenza_A_virus R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 14/4622 14/10654 8.271677784985805e-6 2.181850102530218e-5 8.559174033719175e-6 5526/1452/324/8312/5518/5515/5528/5519/2932/5529/5516/5525/139285/5527 14 Influenza_A_virus R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 14/4622 14/10654 8.271677784985805e-6 2.181850102530218e-5 8.559174033719175e-6 9134/57060/1869/8900/144455/898/890/7157/79733/1820/1017/25946/1027/1026 14 Influenza_A_virus R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 14/4622 14/10654 8.271677784985805e-6 2.181850102530218e-5 8.559174033719175e-6 7159/51230/23368/5458/10000/7157/5457/54971/8626/208/7161/25946/207/10848 14 Influenza_A_virus R-HSA-9027284 Erythropoietin activates RAS 14/4622 14/10654 8.271677784985805e-6 2.181850102530218e-5 8.559174033719175e-6 4893/3717/2885/2056/8660/3845/3265/1399/2057/7409/6464/2889/4067/6654 14 Influenza_A_virus R-HSA-918233 TRAF3-dependent IRF activation pathway 14/4622 14/10654 8.271677784985805e-6 2.181850102530218e-5 8.559174033719175e-6 80143/1387/64135/7187/29110/23586/3661/84282/3665/7706/9641/3456/57506/2033 14 Influenza_A_virus R-HSA-164952 The role of Nef in HIV-1 replication and disease pathogenesis 23/4622 27/10654 9.144247010549519e-6 2.397519736116503e-5 9.405223872575093e-6 162/1174/567/2534/163/1794/5062/5879/161/926/3932/1175/8907/940/1173/160/920/8905/164/919/3055/9844/375 23 Influenza_A_virus R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 23/4622 27/10654 9.144247010549519e-6 2.397519736116503e-5 9.405223872575093e-6 5431/5435/5433/8732/2965/5439/5438/2068/6829/2963/5434/5436/4331/2962/2071/5432/5440/902/5430/5441/5437/2968/1022 23 Influenza_A_virus R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 23/4622 27/10654 9.144247010549519e-6 2.397519736116503e-5 9.405223872575093e-6 5431/5435/5433/8732/2965/5439/5438/2068/6829/2963/5434/5436/4331/2962/2071/5432/5440/902/5430/5441/5437/2968/1022 23 Influenza_A_virus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 19/4622 21/10654 9.175057645367161e-6 2.397519736116503e-5 9.405223872575093e-6 4790/4792/1660/3551/11035/8737/29110/8517/5970/3661/4791/23220/7098/81030/1147/147945/4615/4793/148022 19 Influenza_A_virus R-HSA-445144 Signal transduction by L1 19/4622 21/10654 9.175057645367161e-6 2.397519736116503e-5 9.405223872575093e-6 1459/1460/8829/4684/3688/1457/5605/3690/5879/5594/2260/7410/3685/3674/3897/1956/5058/5595/5604 19 Influenza_A_virus R-HSA-373760 L1CAM interactions 75/4622 119/10654 1.1357914012492283e-5 2.962381304004517e-5 1.1621117832891752e-5 9252/6711/71/7430/1459/51807/347688/1785/1460/10381/8829/4684/3688/1457/5605/7846/3690/1808/6456/1741/1739/6709/5962/163/6196/1759/6197/3312/100133941/5879/161/79861/5594/284217/55800/2260/3672/8650/6714/10376/6195/7410/3685/1213/1211/1175/1173/84617/6712/3674/10382/7277/4478/160/3912/3785/26052/27330/347733/6386/2048/3897/10383/1956/60/84790/5058/8506/7280/5595/5604/10048/6708/1742/287 75 Influenza_A_virus R-HSA-447115 Interleukin-12 family signaling 41/4622 57/10654 1.1544661554136792e-5 3.00548172303226e-5 1.1790196353435792e-5 759/3593/5908/3313/6175/5898/3717/3181/3594/4282/5062/3572/1072/3592/6627/9049/27250/3185/149233/3458/5478/302/51561/7297/821/4478/6774/6772/998/6648/3716/6888/3586/829/6647/6950/4507/6845/375/5721/5034 41 Influenza_A_virus R-HSA-1980143 Signaling by NOTCH1 50/4622 73/10654 1.2244101790137413e-5 3.181645781154666e-5 1.2481269874117771e-5 8454/79718/892/113878/3091/23385/9978/9759/9612/4609/22938/1387/6907/408/83737/9794/7314/79885/2648/9734/55869/51564/3280/10013/3714/8650/102/5664/8850/3066/6233/5663/7090/23220/409/1024/10014/7088/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/92737/3516 50 Influenza_A_virus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 26/4622 32/10654 1.2916514902971573e-5 3.343942191547085e-5 1.3117942035961382e-5 892/4609/4089/22938/4088/1030/7314/5054/7027/6667/4092/6233/1025/4221/1024/60436/8812/1874/905/4087/7311/54778/7316/5933/3065/25937 26 Influenza_A_virus R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 26/4622 32/10654 1.2916514902971573e-5 3.343942191547085e-5 1.3117942035961382e-5 5295/5777/2534/30011/2885/973/933/5336/7409/3710/118788/801/930/7220/6850/4067/29760/695/6654/5293/27071/4690/640/3708/10768/974 26 Influenza_A_virus R-HSA-72766 Translation 162/4622 291/10654 1.3012401082338382e-5 3.362539133661563e-5 1.3190895931312963e-5 6158/6138/5464/6227/6206/1965/6234/6191/6128/6132/1917/6129/1915/6176/8668/6224/6146/6154/8662/26986/6202/65003/6169/6175/6218/6728/6173/64968/11222/6167/6156/6143/1973/28973/51116/6139/6745/64975/3921/8665/10667/6208/6170/6203/51253/6147/8666/6222/64432/8667/7818/2935/6134/6747/6731/55699/6155/6729/6231/6142/8663/23521/23107/8894/1981/6207/64978/1977/6233/28957/51386/6188/26589/10102/1978/64965/7284/6122/1968/6230/6194/2107/6166/1938/1650/1983/6136/6125/1937/23395/6232/6160/6748/29927/1933/60559/6193/6210/6229/6205/54148/64976/140801/6235/6181/8893/1975/55168/7311/6223/25873/8664/6730/9045/6187/6168/6157/6137/1974/55037/6144/9349/4736/8891/51121/6159/56945/6217/1936/6152/79590/51065/6141/10480/1967/25973/6164/63931/57176/64963/9669/6209/11224/6165/6130/8890/6204/64969/6228/7965/5018/6124/90480/2193/3646/6189/6135/6201/6161/51649/8892/6133 162 Influenza_A_virus R-HSA-199977 ER to Golgi Anterograde Transport 93/4622 154/10654 1.4178766538274495e-5 3.6571800037837166e-5 1.4346741826453704e-5 6811/6711/11014/10960/51807/10484/347688/5861/10381/1780/9570/90411/8655/84516/832/3998/55738/7846/100302736/9632/3630/6709/54732/51164/79861/10342/4253/2801/377/22872/1315/8615/55014/11316/8729/10376/1314/10540/83696/27095/7109/378/6396/26286/1453/26958/140735/84364/22820/84617/11258/6712/1783/10382/10802/93661/55860/830/7277/10671/9554/11196/1639/10282/8775/347733/51143/23243/5537/9871/10383/84790/7280/829/1778/9919/10113/55291/51014/1604/1781/10121/22870/10972/6708/9276/287/375/84342/64689/10427/22818/372 93 Influenza_A_virus R-HSA-9020591 Interleukin-12 signaling 35/4622 47/10654 1.4629759122628053e-5 3.766556768588217e-5 1.4775815649683465e-5 759/3593/5908/3313/6175/5898/3717/3181/3594/4282/5062/1072/3592/6627/9049/27250/3185/3458/5478/302/7297/4478/998/6648/3716/6888/3586/829/6647/6950/4507/6845/375/5721/5034 35 Influenza_A_virus R-HSA-164378 PKA activation in glucagon signalling 16/4622 17/10654 1.5624784773232318e-5 3.964403044457461e-5 1.5551946285387675e-5 107/5567/112/5573/111/196883/115/113/5566/5577/109/5575/114/108/2778/5576 16 Influenza_A_virus R-HSA-196299 Beta-catenin phosphorylation cascade 16/4622 17/10654 1.5624784773232318e-5 3.964403044457461e-5 1.5551946285387675e-5 5526/1452/324/8312/5518/5515/5528/5519/2932/23401/5529/5516/1499/5525/139285/5527 16 Influenza_A_virus R-HSA-5655862 Translesion synthesis by POLK 16/4622 17/10654 1.5624784773232318e-5 3.964403044457461e-5 1.5551946285387675e-5 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/51426/7311/5983/7316/10459/5981 16 Influenza_A_virus R-HSA-5656121 Translesion synthesis by POLI 16/4622 17/10654 1.5624784773232318e-5 3.964403044457461e-5 1.5551946285387675e-5 5982/6117/7314/6118/11201/51455/5985/5984/6233/5111/6119/7311/5983/7316/10459/5981 16 Influenza_A_virus R-HSA-8934593 Regulation of RUNX1 Expression and Activity 16/4622 17/10654 1.5624784773232318e-5 3.964403044457461e-5 1.5551946285387675e-5 27327/192669/5371/4343/6714/595/896/26523/5781/27161/894/57690/192670/1021/861/23112 16 Influenza_A_virus R-HSA-9034015 Signaling by NTRK3 (TRKC) 16/4622 17/10654 1.5624784773232318e-5 3.964403044457461e-5 1.5551946285387675e-5 5295/4893/5335/2885/3845/3265/5290/3667/6714/25920/4908/6464/5802/6654/4916/581 16 Influenza_A_virus R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 16/4622 17/10654 1.5624784773232318e-5 3.964403044457461e-5 1.5551946285387675e-5 100302736/929/7314/257397/23118/10454/6233/3656/7189/7311/23643/6885/7099/7316/353376/148022 16 Influenza_A_virus R-HSA-5218920 VEGFR2 mediated vascular permeability 24/4622 29/10654 1.562507923816925e-5 3.964403044457461e-5 1.5551946285387675e-5 857/2475/5062/5879/1500/10000/3728/7410/7409/801/253260/5170/10451/64223/1003/5063/208/79109/5058/1495/1499/207/3320/4846 24 Influenza_A_virus R-HSA-382556 ABC-family proteins mediated transport 66/4622 103/10654 1.719144022511117e-5 4.3539191004901116e-5 1.707997779802235e-5 5689/1965/5682/23/143471/5705/5709/5695/5711/5683/5699/6400/5702/4363/5696/5691/7314/5718/5700/122706/5707/79139/23198/9861/8894/5698/215/5692/5713/5710/5719/10613/6233/1968/5243/5706/10257/5714/22/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/5824/1244/7316/10213/7415/5715/5701/5825/5685/5686/5716/5693/5721 66 Influenza_A_virus R-HSA-171007 p38MAPK events 13/4622 13/10654 1.9097184489050522e-5 4.780149120793526e-5 1.8752034424617324e-5 4893/5898/1432/5603/3845/3265/5899/9261/6714/5600/6300/7867/5900 13 Influenza_A_virus R-HSA-209543 p75NTR recruits signalling complexes 13/4622 13/10654 1.9097184489050522e-5 4.780149120793526e-5 1.8752034424617324e-5 8878/3654/3551/7314/8767/6233/7189/7311/4804/5584/4615/7316/4803 13 Influenza_A_virus R-HSA-209560 NF-kB is activated and signals survival 13/4622 13/10654 1.9097184489050522e-5 4.780149120793526e-5 1.8752034424617324e-5 4790/8878/4792/3654/3551/7314/5970/6233/7189/7311/4804/7316/4803 13 Influenza_A_virus R-HSA-5357786 TNFR1-induced proapoptotic signaling 13/4622 13/10654 1.9097184489050522e-5 4.780149120793526e-5 1.8752034424617324e-5 7124/7375/1540/8737/841/7128/8772/8717/27005/7186/56957/7132/9099 13 Influenza_A_virus R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13/4622 13/10654 1.9097184489050522e-5 4.780149120793526e-5 1.8752034424617324e-5 7531/10971/7533/2810/11200/7465/7534/983/7532/891/1111/7529/995 13 Influenza_A_virus R-HSA-8847993 ERBB2 Activates PTK6 Signaling 13/4622 13/10654 1.9097184489050522e-5 4.780149120793526e-5 1.8752034424617324e-5 2064/5753/145957/9542/1839/2065/2069/3084/10718/1956/685/1950/2066 13 Influenza_A_virus R-HSA-167044 Signalling to RAS 18/4622 20/10654 1.925052900577078e-5 4.780149120793526e-5 1.8752034424617324e-5 4893/5898/1432/5603/2885/3845/3265/5899/9261/6714/4914/5600/6300/6464/7867/6654/5900/4803 18 Influenza_A_virus R-HSA-3232118 SUMOylation of transcription factors 18/4622 20/10654 1.925052900577078e-5 4.780149120793526e-5 1.8752034424617324e-5 9112/6613/7022/6612/4286/6670/51588/7157/7158/9063/8554/7020/1029/7329/7021/3090/7341/4193 18 Influenza_A_virus R-HSA-5654719 SHC-mediated cascade:FGFR4 18/4622 20/10654 1.925052900577078e-5 4.780149120793526e-5 1.8752034424617324e-5 4893/9965/2264/2885/3845/3265/8823/8074/2249/2247/2246/2251/6464/6654/8817/2254/152831/26281 18 Influenza_A_virus R-HSA-5654720 PI-3K cascade:FGFR4 18/4622 20/10654 1.925052900577078e-5 4.780149120793526e-5 1.8752034424617324e-5 5295/9965/2264/2885/5290/8823/8074/2249/2247/2246/2251/5781/2549/8817/2254/152831/26281/10818 18 Influenza_A_virus R-HSA-622312 Inflammasomes 18/4622 20/10654 1.925052900577078e-5 4.780149120793526e-5 1.8752034424617324e-5 834/4790/7295/29108/10628/5970/5027/598/4791/351/3326/4210/114548/9447/596/10910/58484/22861 18 Influenza_A_virus R-HSA-4791275 Signaling by WNT in cancer 27/4622 34/10654 1.9293003920750087e-5 4.7822020356752874e-005 1.876008779901231e-5 27123/5526/1452/324/8312/5518/80351/5515/8322/5528/89780/5519/2932/4040/7855/4041/8658/6934/5529/5516/1487/1499/5525/139285/54894/5527/1488 27 Influenza_A_virus R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 20/4622 23/10654 1.9661931394220857e-5 4.839327480479007e-5 1.8984185056317766e-5 5431/5435/5433/5439/51497/5438/6829/25920/2963/5434/5436/2962/5432/22916/5440/5430/5441/4686/9150/5437 20 Influenza_A_virus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 20/4622 23/10654 1.9661931394220857e-5 4.839327480479007e-5 1.8984185056317766e-5 7321/8239/9612/4089/23327/4088/7314/6497/51592/7323/6233/60436/142/4087/7311/64750/54778/7316/9611/3065 20 Influenza_A_virus R-HSA-5654695 PI-3K cascade:FGFR2 20/4622 23/10654 1.9661931394220857e-5 4.839327480479007e-5 1.8984185056317766e-5 5295/2885/2252/5290/8823/8074/2249/2248/2247/2246/2251/5781/2263/2549/8817/2254/26281/10818/2255/27006 20 Influenza_A_virus R-HSA-5654699 SHC-mediated cascade:FGFR2 20/4622 23/10654 1.9661931394220857e-5 4.839327480479007e-5 1.8984185056317766e-5 4893/2885/2252/3845/3265/8823/8074/2249/2248/2247/2246/2251/6464/2263/6654/8817/2254/26281/2255/27006 20 Influenza_A_virus R-HSA-381119 Unfolded Protein Response (UPR) 61/4622 94/10654 1.9986450842692746e-5 4.910555057659834e-5 1.92636035316676e-5 5393/10525/1965/2673/23404/5526/811/3576/9570/55738/3309/4801/55062/6745/6347/11340/9820/10488/7094/9114/468/22872/51726/3068/8894/9451/2931/8570/23016/118460/1968/6464/37/5073/7184/118/1051/84447/5611/4800/1639/10954/4189/22926/51010/64764/56915/167227/22894/4000/10113/440/9709/4802/116138/2081/30827/51013/467/54512/7709 61 Influenza_A_virus R-HSA-977444 GABA B receptor activation 30/4622 39/10654 2.056620916611456e-5 5.03529954715029e-5 1.975296336168437e-5 2788/2770/2550/107/9568/2774/2782/2773/2787/112/111/2792/2785/2783/2784/2771/196883/115/113/2786/109/54331/3766/94235/114/108/55970/346562/2793/2790 30 Influenza_A_virus R-HSA-991365 Activation of GABAB receptors 30/4622 39/10654 2.056620916611456e-5 5.03529954715029e-5 1.975296336168437e-5 2788/2770/2550/107/9568/2774/2782/2773/2787/112/111/2792/2785/2783/2784/2771/196883/115/113/2786/109/54331/3766/94235/114/108/55970/346562/2793/2790 30 Influenza_A_virus R-HSA-373755 Semaphorin interactions 45/4622 65/10654 2.1699085421689602e-5 5.303377870545816e-5 2.080460711207266e-5 5361/7305/2064/8829/3688/54209/23365/2534/9475/1808/4628/6093/5362/5062/5879/1400/23396/1072/7094/389/10371/3672/9855/2932/55558/80031/23129/4233/5063/3326/387/5058/1020/3984/4627/3985/10398/9826/4637/3320/91584/103910/8851/6237/2242 45 Influenza_A_virus R-HSA-182971 EGFR downregulation 25/4622 31/10654 2.4427242216666183e-5 5.9390060206781433e-5 2.329811111191411e-5 6456/30011/2885/8874/7314/1839/8027/2060/2069/9146/6455/6233/29924/5782/998/7311/1956/685/58513/7316/1950/867/5774/10254/6457 25 Influenza_A_virus R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 25/4622 31/10654 2.4427242216666183e-5 5.9390060206781433e-5 2.329811111191411e-5 857/5526/1452/324/8312/1855/5518/5515/1856/5528/89780/5519/2932/1857/4040/7855/4041/23401/5529/5516/1499/5525/139285/1455/5527 25 Influenza_A_virus R-HSA-5654687 Downstream signaling of activated FGFR1 25/4622 31/10654 2.4427242216666183e-5 5.9390060206781433e-5 2.329811111191411e-5 5295/4893/5335/2885/3845/3265/23769/5290/8074/2260/2249/2248/2247/2246/2251/5781/6464/6654/2549/10817/2254/26281/10818/2255/27006 25 Influenza_A_virus R-HSA-110312 Translesion synthesis by REV1 15/4622 16/10654 3.404837646575035e-5 8.221006960124178e-5 3.2250166600592545e-5 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/7311/5983/7316/10459/5981 15 Influenza_A_virus R-HSA-1295596 Spry regulation of FGF signaling 15/4622 16/10654 3.404837646575035e-5 8.221006960124178e-5 3.2250166600592545e-5 8569/2885/5518/7314/5515/5594/6714/6233/5781/673/7311/5595/5516/7316/867 15 Influenza_A_virus R-HSA-1433559 Regulation of KIT signaling 15/4622 16/10654 3.404837646575035e-5 8.221006960124178e-5 3.2250166600592545e-5 5777/5578/2534/2885/10603/3815/9306/6714/7525/3932/8651/4067/6654/867/4254 15 Influenza_A_virus R-HSA-9614657 FOXO-mediated transcription of cell death genes 15/4622 16/10654 3.404837646575035e-5 8.221006960124178e-5 3.2250166600592545e-5 2308/65018/356/1387/4801/604/4303/4800/10370/6794/27113/2309/10018/4802/2033 15 Influenza_A_virus R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 21/4622 25/10654 3.5612000861734746e-5 8.568946162599859e-5 3.361509638366483e-5 51807/10381/10576/7846/10574/10693/79861/10575/10376/84617/10382/7277/347733/10383/84790/22948/7280/10694/7203/908/6950 21 Influenza_A_virus R-HSA-429947 Deadenylation of mRNA 21/4622 25/10654 3.5612000861734746e-5 8.568946162599859e-5 3.361509638366483e-5 26986/25904/1973/55571/57472/85456/29883/1981/1977/9924/5073/4850/255967/246175/4848/23019/1975/1974/4849/9337/9775 21 Influenza_A_virus R-HSA-111465 Apoptotic cleavage of cellular proteins 29/4622 38/10654 3.6884640381734986e-5 8.844721655860293e-5 3.469693534148944e-5 660/836/324/9414/6709/6093/2934/22985/63967/841/100506658/7082/5339/28988/10134/999/5588/5580/839/1828/5747/118/8428/4000/51765/1499/329/4137/7431 29 Influenza_A_virus R-HSA-5696394 DNA Damage Recognition in GG-NER 29/4622 38/10654 3.6884640381734986e-5 8.844721655860293e-5 3.469693534148944e-5 10445/9978/10980/10987/7314/83444/86/1643/29844/6233/8607/5886/8451/8450/1642/142/1069/2873/7311/60/8533/51138/7528/9318/7316/4798/5887/50813/7508 29 Influenza_A_virus R-HSA-202427 Phosphorylation of CD3 and TCR zeta chains 19/4622 22/10654 3.971322100501044e-5 9.458106126917307e-5 3.7103179671138604e-5 3115/3113/3117/26191/3127/3126/1445/916/3932/3120/3123/3122/920/5795/3125/3119/919/915/917 19 Influenza_A_virus R-HSA-389357 CD28 dependent PI3K/Akt signaling 19/4622 22/10654 3.971322100501044e-5 9.458106126917307e-5 3.7103179671138604e-5 5295/941/2534/2475/1326/5290/9020/10000/3932/940/253260/5170/64223/8503/208/79109/207/942/5296 19 Influenza_A_virus R-HSA-5655332 Signaling by FGFR3 in disease 19/4622 22/10654 3.971322100501044e-5 9.458106126917307e-5 3.7103179671138604e-5 5295/4893/5335/2885/3845/3265/5290/8823/8074/2249/2247/2246/6654/2549/8817/2254/26281/10818/2261 19 Influenza_A_virus R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 19/4622 22/10654 3.971322100501044e-5 9.458106126917307e-5 3.7103179671138604e-5 5295/4893/5335/2885/3845/3265/5290/8823/8074/2249/2247/2246/6654/2549/8817/2254/26281/10818/2261 19 Influenza_A_virus R-HSA-110320 Translesion Synthesis by POLH 17/4622 19/10654 4.0190443490435016e-5 9.55548299313404e-5 3.748517912373191e-5 5982/25898/6117/55666/7314/6118/5985/5984/6233/5111/6119/5429/7311/5983/7316/7415/5981 17 Influenza_A_virus R-HSA-170968 Frs2-mediated activation 12/4622 12/10654 4.408508402005982e-5 1.0271824576673939e-4 4.0295313639388007e-5 5605/1399/5594/4914/673/2889/7529/5595/5604/10818/4803/5906 12 Influenza_A_virus R-HSA-190873 Gap junction degradation 12/4622 12/10654 4.408508402005982e-5 1.0271824576673939e-4 4.0295313639388007e-5 71/1212/1785/2697/1759/4646/1601/1213/1211/1173/8218/60 12 Influenza_A_virus R-HSA-2029481 FCGR activation 12/4622 12/10654 4.408508402005982e-5 1.0271824576673939e-4 4.0295313639388007e-5 2268/2534/6714/7525/2214/2209/6850/4067/919/3055/917/2212 12 Influenza_A_virus R-HSA-210990 PECAM1 interactions 12/4622 12/10654 4.408508402005982e-5 1.0271824576673939e-4 4.0295313639388007e-5 5777/5335/5175/2534/3690/3635/6714/7525/3685/3932/5781/4067 12 Influenza_A_virus R-HSA-3371511 HSF1 activation 12/4622 12/10654 4.408508402005982e-5 1.0271824576673939e-4 4.0295313639388007e-5 7531/1915/6117/6118/10013/3297/6119/3281/3326/10728/7415/3320 12 Influenza_A_virus R-HSA-389359 CD28 dependent Vav1 pathway 12/4622 12/10654 4.408508402005982e-5 1.0271824576673939e-4 4.0295313639388007e-5 941/2534/2885/5062/5879/7409/3932/940/5063/998/5058/942 12 Influenza_A_virus R-HSA-417957 P2Y receptors 12/4622 12/10654 4.408508402005982e-5 1.0271824576673939e-4 4.0295313639388007e-5 10161/64805/2840/5028/5029/53829/27334/9934/5032/5031/5030/2846 12 Influenza_A_virus R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 12/4622 12/10654 4.408508402005982e-5 1.0271824576673939e-4 4.0295313639388007e-5 7159/23368/8797/7157/8626/7161/8795/8793/3486/355/8794/124446 12 Influenza_A_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 12/4622 12/10654 4.408508402005982e-5 1.0271824576673939e-4 4.0295313639388007e-5 7187/7314/29110/3661/6233/10010/3665/7098/7311/9641/7316/148022 12 Influenza_A_virus R-HSA-9020558 Interleukin-2 signaling 12/4622 12/10654 4.408508402005982e-5 1.0271824576673939e-4 4.0295313639388007e-5 6776/3558/3718/3932/6777/6464/6850/3716/2185/3561/3560/3559 12 Influenza_A_virus R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 12/4622 12/10654 4.408508402005982e-5 1.0271824576673939e-4 4.0295313639388007e-5 5295/5291/3717/2056/8660/5290/5294/2057/4067/5293/2549/23533 12 Influenza_A_virus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12/4622 12/10654 4.408508402005982e-5 1.0271824576673939e-4 4.0295313639388007e-5 64135/3551/8737/841/8517/23586/84282/8772/7706/843/1147/57506 12 Influenza_A_virus R-HSA-157118 Signaling by NOTCH 132/4622 235/10654 4.5748484065575096e-5 1.0641660686135439e-4 4.174614274133397e-5 8454/5689/3725/79718/5682/892/4904/113878/27327/3091/23385/5705/5709/9978/1869/5695/9759/9612/4609/11060/22938/5711/1387/4088/6907/5683/408/5699/6400/4853/5702/192669/83737/9794/4343/5696/5691/7314/5718/23286/79885/2648/9734/7027/55869/5700/5707/51564/3280/10013/7534/4854/3714/8650/102/5664/9861/5870/8850/5698/5692/5713/595/5710/3002/3066/7157/5719/6233/2324/26523/5663/1999/23129/7090/23220/409/5706/10460/1024/5714/6772/10014/5688/5687/5708/59/4855/7088/5704/7311/1956/5694/4851/27161/5684/8841/5720/5584/23462/207/5690/57690/5717/9491/6500/51548/10197/192670/488/7316/10213/1950/9611/6484/1871/5715/5701/5685/5686/2033/55294/3065/861/92737/2683/23112/5716/1385/3516/5693/5721 132 Influenza_A_virus R-HSA-432720 Lysosome Vesicle Biogenesis 27/4622 35/10654 4.94507984753514e-5 1.1483756855239411e-4 4.504959959023969e-5 8906/162/27243/1212/1174/1785/408/6456/3312/9146/4074/6844/1213/1211/23431/8907/351/9179/9829/8905/8673/164/1777/81567/10717/6845/375 27 Influenza_A_virus R-HSA-5693532 DNA Double-Strand Break Repair 97/4622 166/10654 6.0488589303166596e-5 1.402372269416698e-4 5.501362490521043e-5 83990/151987/9156/1763/7486/27343/5982/11200/472/6613/2140/64421/4683/165918/84126/8900/8924/2067/672/6117/7334/10714/83695/7314/6118/25/5888/322/51588/51720/63967/5531/116028/2070/890/7517/9656/5985/7157/5984/6233/7158/6047/5884/5810/5424/8467/80010/3838/7515/54107/580/11073/5591/5425/641/5111/6119/3364/22976/10524/5427/144715/5889/5429/142/1111/7329/79728/51426/7311/23030/5536/5983/2547/56655/1017/5893/5883/10111/57804/7520/675/51548/545/7336/29086/7316/5426/7341/23514/5932/9025/79184/7156/5599/5981 97 Influenza_A_virus R-HSA-451326 Activation of kainate receptors upon glutamate binding 25/4622 32/10654 6.553698262271798e-5 1.516899034876817e-4 5.950639237789486e-5 2788/5331/2898/2782/1741/1739/2787/10681/2792/2785/2783/2784/801/2791/23236/2786/54331/59345/51764/94235/5330/55970/2793/1742/2790 25 Influenza_A_virus R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 20/4622 24/10654 6.958221123159923e-5 1.605213387818081e-4 6.297087380869065e-5 1763/5982/5422/6117/10714/6118/5985/5984/23649/5424/54107/5425/5111/6119/5427/5983/56655/57804/5426/5981 20 Influenza_A_virus R-HSA-933542 TRAF6 mediated NF-kB activation 20/4622 24/10654 6.958221123159923e-5 1.605213387818081e-4 6.297087380869065e-5 4790/4792/64135/3551/4214/8517/5970/23586/84282/4791/351/7706/7189/1147/7186/57506/4793/3146/6288/6285 20 Influenza_A_virus R-HSA-74752 Signaling by Insulin receptor 51/4622 78/10654 7.009293268786689e-5 1.614331464540987e-4 6.332856660084739e-5 5295/3643/4893/5291/9965/2264/3630/2885/8660/9846/2252/3845/3265/54106/5290/3667/8823/526/9114/5594/8074/2260/2249/2248/2247/529/2246/2251/5781/30849/5170/6464/2322/5140/2263/208/6654/2549/5595/8817/2254/152831/5289/26281/10818/23545/2261/2255/27006/5296/2887 51 Influenza_A_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 40/4622 58/10654 7.098618596363762e-5 1.621547189169369e-4 6.361163207267837e-5 8454/79718/892/23385/9978/9759/9612/4609/22938/1387/6907/9794/7314/79885/2648/9734/55869/51564/3280/10013/3714/102/5664/8850/3066/6233/5663/1024/10014/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 40 Influenza_A_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 40/4622 58/10654 7.098618596363762e-5 1.621547189169369e-4 6.361163207267837e-5 8454/79718/892/23385/9978/9759/9612/4609/22938/1387/6907/9794/7314/79885/2648/9734/55869/51564/3280/10013/3714/102/5664/8850/3066/6233/5663/1024/10014/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 40 Influenza_A_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 40/4622 58/10654 7.098618596363762e-5 1.621547189169369e-4 6.361163207267837e-5 8454/79718/892/23385/9978/9759/9612/4609/22938/1387/6907/9794/7314/79885/2648/9734/55869/51564/3280/10013/3714/102/5664/8850/3066/6233/5663/1024/10014/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 40 Influenza_A_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 40/4622 58/10654 7.098618596363762e-5 1.621547189169369e-4 6.361163207267837e-5 8454/79718/892/23385/9978/9759/9612/4609/22938/1387/6907/9794/7314/79885/2648/9734/55869/51564/3280/10013/3714/102/5664/8850/3066/6233/5663/1024/10014/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 40 Influenza_A_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 40/4622 58/10654 7.098618596363762e-5 1.621547189169369e-4 6.361163207267837e-5 8454/79718/892/23385/9978/9759/9612/4609/22938/1387/6907/9794/7314/79885/2648/9734/55869/51564/3280/10013/3714/102/5664/8850/3066/6233/5663/1024/10014/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 40 Influenza_A_virus R-HSA-111447 Activation of BAD and translocation to mitochondria 14/4622 15/10654 7.39226783100312e-5 1.6831254768310037e-4 6.602728510119365e-5 7531/10971/7533/2810/637/7534/10000/572/7532/208/7529/596/207/5534 14 Influenza_A_virus R-HSA-6785631 ERBB2 Regulates Cell Motility 14/4622 15/10654 7.39226783100312e-5 1.6831254768310037e-4 6.602728510119365e-5 2064/145957/9542/1839/2065/2069/1729/3084/10718/387/1956/685/1950/2066 14 Influenza_A_virus R-HSA-111931 PKA-mediated phosphorylation of CREB 18/4622 21/10654 7.970335716819254e-5 1.805920475220959e-4 7.084440686620886e-5 107/5567/112/5573/111/5613/196883/115/801/113/5566/5577/109/5575/114/108/5576/1385 18 Influenza_A_virus R-HSA-5218921 VEGFR2 mediated cell proliferation 18/4622 21/10654 7.970335716819254e-5 1.805920475220959e-4 7.084440686620886e-5 4893/5335/5579/5578/3845/3265/8877/5921/6714/5580/3791/3710/801/5170/5590/7422/3708/10768 18 Influenza_A_virus R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 18/4622 21/10654 7.970335716819254e-5 1.805920475220959e-4 7.084440686620886e-5 5982/6117/10714/6118/328/5985/5984/5424/54107/5425/5111/6119/5427/5983/56655/57804/5426/5981 18 Influenza_A_virus R-HSA-9619483 Activation of AMPK downstream of NMDARs 23/4622 29/10654 8.550843411756088e-5 1.9343170047953092e-4 7.588127095085884e-5 5563/51807/347688/53632/10381/7846/79861/51422/10376/801/84617/10382/7277/10645/5571/347733/5562/10383/84790/5564/5565/7280/4137 23 Influenza_A_virus R-HSA-1660499 Synthesis of PIPs at the plasma membrane 37/4622 53/10654 8.810361762843815e-5 1.9898038359379084e-4 7.805796239166105e-5 5295/5291/5286/55300/8871/660/8396/54477/23396/3635/5290/5868/59339/81846/79837/8395/55361/146850/5294/8394/22874/8867/66036/8503/3636/59338/5867/5293/5305/8897/64419/5287/23533/5728/5296/375/4952 37 Influenza_A_virus R-HSA-9006931 Signaling by Nuclear Receptors 162/4622 299/10654 9.090178036228788e-5 2.0496885313948138e-4 8.040717753608148e-5 5295/2788/3725/4893/857/79718/5160/2770/10901/27327/10274/8050/5431/5435/5433/1509/5469/1105/9612/4609/1387/6907/8312/2782/5439/192669/10499/1386/5914/4343/3845/1071/3265/8877/2773/10062/2787/6387/1839/5290/5594/2069/10681/1737/5481/5438/348/4313/1655/6667/2792/6714/2099/8850/5467/10000/2785/595/2783/2784/2771/7514/1025/2353/6257/26523/801/2791/5105/5170/2963/3838/5434/5590/6464/112724/1374/7090/5241/5747/5436/1903/3315/4318/200845/5885/2962/8503/10524/5346/8243/4602/2786/208/3326/23030/6908/1956/5536/3169/51109/858/23189/5432/3480/10728/5595/7528/27161/596/5440/8841/685/54331/2309/9687/59345/8204/5430/207/5451/2625/57690/1027/51764/94235/5441/10735/6720/192670/2100/1950/9611/55970/2874/2194/4314/346562/2289/7391/5163/5437/2793/3320/2033/4846/9126/3065/2066/861/23028/6256/23112/10498/1385/1738/5296/3276/8202/8648/2288/2790 162 Influenza_A_virus R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 79/4622 132/10654 9.44768875052814e-5 2.1268709940802479e-4 8.343496633655669e-5 83990/151987/9156/1763/7486/5982/472/6613/4683/165918/84126/8900/8924/2067/672/6117/7334/10714/83695/7314/6118/25/5888/51588/51720/63967/5531/116028/890/7517/9656/5985/5984/6233/7158/6047/5884/5810/5424/80010/54107/580/11073/5425/641/5111/6119/3364/10524/5427/144715/5889/5429/1111/7329/79728/51426/7311/5983/56655/1017/5893/5883/10111/57804/675/51548/545/7336/29086/7316/5426/7341/23514/5932/9025/79184/7156/5981 79 Influenza_A_virus R-HSA-196025 Formation of annular gap junctions 11/4622 11/10654 1.0175613732932034e-4 2.2544386685640228e-4 8.843931528663926e-5 71/1212/1785/2697/1759/1601/1213/1211/1173/8218/60 11 Influenza_A_virus R-HSA-3371378 Regulation by c-FLIP 11/4622 11/10654 1.0175613732932034e-4 2.2544386685640228e-4 8.843931528663926e-5 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355 11 Influenza_A_virus R-HSA-5218900 CASP8 activity is inhibited 11/4622 11/10654 1.0175613732932034e-4 2.2544386685640228e-4 8.843931528663926e-5 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355 11 Influenza_A_virus R-HSA-5655291 Signaling by FGFR4 in disease 11/4622 11/10654 1.0175613732932034e-4 2.2544386685640228e-4 8.843931528663926e-5 5295/4893/5335/2264/2885/3845/3265/5290/6654/2549/10818 11 Influenza_A_virus R-HSA-69416 Dimerization of procaspase-8 11/4622 11/10654 1.0175613732932034e-4 2.2544386685640228e-4 8.843931528663926e-5 356/8737/841/8797/8772/8717/8743/8837/8795/7186/355 11 Influenza_A_virus R-HSA-8875555 MET activates RAP1 and RAC1 11/4622 11/10654 1.0175613732932034e-4 2.2544386685640228e-4 8.843931528663926e-5 5908/3082/2885/1399/5879/85440/4233/2889/2549/1398/5906 11 Influenza_A_virus R-HSA-8934903 Receptor Mediated Mitophagy 11/4622 11/10654 1.0175613732932034e-4 2.2544386685640228e-4 8.843931528663926e-5 1459/9140/1460/9474/1457/84557/139341/192111/6714/8408/81631 11 Influenza_A_virus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 11/4622 11/10654 1.0175613732932034e-4 2.2544386685640228e-4 8.843931528663926e-5 7314/257397/23118/10454/6233/7098/7189/7311/6885/7316/148022 11 Influenza_A_virus R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 11/4622 11/10654 1.0175613732932034e-4 2.2544386685640228e-4 8.843931528663926e-5 627/4893/2885/3845/3265/4909/5781/6654/4915/10817/10818 11 Influenza_A_virus R-HSA-9614399 Regulation of localization of FOXO transcription factors 11/4622 11/10654 1.0175613732932034e-4 2.2544386685640228e-4 8.843931528663926e-5 2308/10971/2810/7534/10000/7532/4303/208/7529/2309/207 11 Influenza_A_virus R-HSA-5654693 FRS-mediated FGFR1 signaling 19/4622 23/10654 0.00013495684665626041 2.9852796143267727e-4 1.1710945554282425e-4 4893/2885/3845/3265/8074/2260/2249/2248/2247/2246/2251/5781/6654/10817/2254/26281/10818/2255/27006 19 Influenza_A_virus R-HSA-1855204 Synthesis of IP3 and IP4 in the cytosol 22/4622 28/10654 1.5811483006639122e-4 3.4803835320150407e-4 1.3653187411940643e-4 5335/5331/80271/51196/3635/5336/113026/5332/801/3633/8867/89869/3636/23236/84812/9651/5330/5333/3705/5728/23007/4952 22 Influenza_A_virus R-HSA-5654706 FRS-mediated FGFR3 signaling 17/4622 20/10654 1.5884995890353177e-4 3.4803835320150407e-4 1.3653187411940643e-4 4893/2885/3845/3265/8823/8074/2249/2247/2246/5781/6654/8817/10817/2254/26281/10818/2261 17 Influenza_A_virus R-HSA-70326 Glucose metabolism 57/4622 91/10654 1.5924458297828499e-4 3.4803835320150407e-4 1.3653187411940643e-4 23165/7167/348995/57122/3099/6576/23511/23279/23225/9972/5518/4191/8021/55746/5515/2597/5567/10762/5528/79902/5519/9883/226/2821/8604/5208/6396/129401/5105/4928/5903/55706/7175/2805/4927/5566/2023/4190/8086/5516/81929/9631/5315/79023/23636/5214/83440/53371/5230/10165/3098/9688/5209/5224/5213/8480/5223 57 Influenza_A_virus R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 13/4622 14/10654 1.5982877164189243e-4 3.4803835320150407e-4 1.3653187411940643e-4 5861/2801/5594/983/8548/8615/9133/891/5347/5595/5862/26003/64689 13 Influenza_A_virus R-HSA-177504 Retrograde neurotrophin signalling 13/4622 14/10654 1.5982877164189243e-4 3.4803835320150407e-4 1.3653187411940643e-4 1785/6456/163/1759/161/4914/1213/1211/1175/1173/160/26052/4803 13 Influenza_A_virus R-HSA-399955 SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion 13/4622 14/10654 1.5982877164189243e-4 3.4803835320150407e-4 1.3653187411940643e-4 5361/8829/2534/5362/5879/23396/7094/10371/9855/55558/91584/6237/2242 13 Influenza_A_virus R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 13/4622 14/10654 1.5982877164189243e-4 3.4803835320150407e-4 1.3653187411940643e-4 4436/9156/6117/10714/6118/5424/2956/4292/5425/5111/6119/57804/5395 13 Influenza_A_virus R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 13/4622 14/10654 1.5982877164189243e-4 3.4803835320150407e-4 1.3653187411940643e-4 79370/7159/23368/332/64065/7157/604/5875/8626/7161/10397/9540/5876 13 Influenza_A_virus R-HSA-877312 Regulation of IFNG signaling 13/4622 14/10654 1.5982877164189243e-4 3.4803835320150407e-4 1.3653187411940643e-4 5777/5770/9021/3459/3717/3458/5781/8554/6772/8651/3716/3460/7341 13 Influenza_A_virus R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 13/4622 14/10654 1.5982877164189243e-4 3.4803835320150407e-4 1.3653187411940643e-4 4893/5753/9564/3845/3265/5829/5879/5921/1793/387/63916/1398/9844 13 Influenza_A_virus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 15/4622 17/10654 1.7222531415963605e-4 3.7386799564467576e-4 1.4666457776588818e-4 4790/4792/1660/3551/11035/8737/8517/5970/4791/7098/81030/1147/4615/4793/148022 15 Influenza_A_virus R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 15/4622 17/10654 1.7222531415963605e-4 3.7386799564467576e-4 1.4666457776588818e-4 2308/857/2290/57060/4089/1647/4088/5934/4303/901/9314/4087/2309/1027/1026 15 Influenza_A_virus R-HSA-5674135 MAP2K and MAPK activation 29/4622 40/10654 1.793932143898496e-4 3.8882436235195304e-4 1.5253180693123073e-4 4893/71/5908/5605/5037/3690/408/5894/8826/4140/3845/3265/8844/7094/5594/7414/6714/2335/1445/369/283455/3674/409/673/60/7529/5595/5604/5906 29 Influenza_A_virus R-HSA-416482 G alpha (12/13) signalling events 51/4622 80/10654 1.840938902740813e-4 3.983951371566032e-4 1.562863236643252e-4 2788/9639/7984/29/1894/10276/9138/23365/9475/2768/2782/6093/8874/2787/389/10681/6453/9828/2792/2785/2783/2784/7410/7409/2791/146/148/7204/7074/6915/10451/50650/695/2786/6654/387/147/54331/59345/57580/11214/51764/94235/55970/4168/23263/50649/9826/2793/2790/10672 51 Influenza_A_virus R-HSA-5693538 Homology Directed Repair 81/4622 138/10654 1.9393079366017576e-4 4.1903438877422835e-4 1.6438289025779156e-4 83990/151987/9156/1763/7486/5982/472/6613/4683/165918/84126/8900/8924/2067/672/6117/7334/10714/83695/7314/6118/25/5888/51588/51720/63967/5531/116028/890/7517/9656/5985/5984/6233/7158/6047/5884/5810/5424/80010/7515/54107/580/11073/5425/641/5111/6119/3364/10524/5427/144715/5889/5429/142/1111/7329/79728/51426/7311/5983/56655/1017/5893/5883/10111/57804/675/51548/545/7336/29086/7316/5426/7341/23514/5932/9025/79184/7156/5981 81 Influenza_A_virus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 20/4622 25/10654 2.0546305271105703e-4 4.425845110786714e-4 1.73621361548067e-4 9252/1432/6196/5518/6197/51231/5515/1849/5594/5528/9261/5519/5598/6195/5600/1846/5595/5516/4205/1385 20 Influenza_A_virus R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 20/4622 25/10654 2.0546305271105703e-4 4.425845110786714e-4 1.73621361548067e-4 3107/10484/811/567/3106/3309/9632/3133/22872/10134/6396/3135/10802/6890/821/2923/9871/3105/3134/10427 20 Influenza_A_virus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 23/4622 30/10654 2.1573624211183295e-4 4.639988714959115e-4 1.8202199536885015e-4 11065/7321/65264/8239/3093/7347/7328/7332/7314/7324/6233/7874/7326/7317/8078/7327/7311/997/7319/7320/7316/7322/27338 23 Influenza_A_virus R-HSA-1250342 PI3K events in ERBB4 signaling 10/4622 10/10654 2.3484222153800666e-4 4.959356883838872e-4 1.9455048087343215e-4 5295/145957/9542/1839/5290/2069/3084/10718/685/2066 10 Influenza_A_virus R-HSA-170660 Adenylate cyclase activating pathway 10/4622 10/10654 2.3484222153800666e-4 4.959356883838872e-4 1.9455048087343215e-4 107/2774/112/111/196883/115/113/109/114/108 10 Influenza_A_virus R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 10/4622 10/10654 2.3484222153800666e-4 4.959356883838872e-4 1.9455048087343215e-4 5563/53632/1432/51422/5600/6300/5571/5564/5565/10891 10 Influenza_A_virus R-HSA-2562578 TRIF-mediated programmed cell death 10/4622 10/10654 2.3484222153800666e-4 4.959356883838872e-4 1.9455048087343215e-4 100302736/929/11035/8737/841/8772/23643/7099/353376/148022 10 Influenza_A_virus R-HSA-390450 Folding of actin by CCT/TriC 10/4622 10/10654 2.3484222153800666e-4 4.959356883838872e-4 1.9455048087343215e-4 10576/10574/10693/10575/60/22948/10694/7203/908/6950 10 Influenza_A_virus R-HSA-399997 Acetylcholine regulates insulin secretion 10/4622 10/10654 2.3484222153800666e-4 4.959356883838872e-4 1.9455048087343215e-4 5331/5578/2769/2776/1131/23236/4082/5330/2767/9630 10 Influenza_A_virus R-HSA-450341 Activation of the AP-1 family of transcription factors 10/4622 10/10654 2.3484222153800666e-4 4.959356883838872e-4 1.9455048087343215e-4 3725/1432/1386/5601/5594/2353/5600/5602/5595/5599 10 Influenza_A_virus R-HSA-74749 Signal attenuation 10/4622 10/10654 2.3484222153800666e-4 4.959356883838872e-4 1.9455048087343215e-4 3643/3630/2885/8660/3667/5594/6464/6654/5595/2887 10 Influenza_A_virus R-HSA-8853334 Signaling by FGFR3 fusions in cancer 10/4622 10/10654 2.3484222153800666e-4 4.959356883838872e-4 1.9455048087343215e-4 5295/4893/2885/3845/3265/5290/6654/2549/10818/2261 10 Influenza_A_virus R-HSA-8875656 MET receptor recycling 10/4622 10/10654 2.3484222153800666e-4 4.959356883838872e-4 1.9455048087343215e-4 3082/2885/1399/382/4233/5867/2549/53916/1398/23163 10 Influenza_A_virus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 10/4622 10/10654 2.3484222153800666e-4 4.959356883838872e-4 1.9455048087343215e-4 7314/257397/23118/10454/6233/3656/7189/7311/6885/7316 10 Influenza_A_virus R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 10/4622 10/10654 2.3484222153800666e-4 4.959356883838872e-4 1.9455048087343215e-4 2308/7295/1387/10628/23411/8850/4303/23410/2309/2033 10 Influenza_A_virus R-HSA-198753 ERK/MAPK targets 18/4622 22/10654 2.5965896990251004e-4 5.458695337198633e-4 2.1413901593859554e-4 9252/1432/6196/5518/6197/51231/5515/1849/5594/5528/5519/5598/6195/5600/1846/5595/5516/4205 18 Influenza_A_virus R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 18/4622 22/10654 2.5965896990251004e-4 5.458695337198633e-4 2.1413901593859554e-4 3725/7531/356/7001/823/2801/993/351/6648/1020/4000/994/2309/10018/824/995/8851/5052 18 Influenza_A_virus R-HSA-8863678 Neurodegenerative Diseases 18/4622 22/10654 2.5965896990251004e-4 5.458695337198633e-4 2.1413901593859554e-4 3725/7531/356/7001/823/2801/993/351/6648/1020/4000/994/2309/10018/824/995/8851/5052 18 Influenza_A_virus R-HSA-1251985 Nuclear signaling by ERBB4 24/4622 32/10654 2.8100995865269757e-4 5.889833915989073e-4 2.310521399164451e-4 51741/23385/6776/10413/145957/9542/6387/1839/2069/23118/348/6714/2099/5664/3925/5663/5241/3084/10718/685/9611/2066/6285/11033 24 Influenza_A_virus R-HSA-5626467 RHO GTPases activate IQGAPs 24/4622 32/10654 2.8100995865269757e-4 5.889833915989073e-4 2.310521399164451e-4 71/6249/51807/347688/10381/7846/8826/5879/79861/999/10376/801/4221/84617/10382/7277/347733/998/10383/60/84790/7280/1495/1499 24 Influenza_A_virus R-HSA-1538133 G0 and Early G1 21/4622 27/10654 2.898667969815796e-4 6.066373984734255e-4 2.3797762563410488e-4 9134/1869/4609/5928/8900/7027/7153/898/5934/993/890/983/1859/286826/5111/1874/55957/1017/4149/5933/3065 21 Influenza_A_virus R-HSA-163615 PKA activation 16/4622 19/10654 3.1416872104542495e-4 6.565140090007535e-4 2.57543708071224e-4 107/5567/112/5573/111/196883/115/801/113/5566/5577/109/5575/114/108/5576 16 Influenza_A_virus R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 33/4622 48/10654 3.328802932917775e-4 6.945770895849328e-4 2.724754639513215e-4 5431/5435/5433/2965/5439/11198/51497/5438/2068/1025/6829/25920/2963/5434/5436/4331/2962/8812/905/2071/5432/22916/5440/902/5430/6749/5441/4686/9150/5437/2968/1022/8178 33 Influenza_A_virus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 12/4622 13/10654 3.4393987839217104e-4 7.165841281553729e-4 2.8110859932907857e-4 2064/9542/7314/2065/9101/10000/6233/3084/208/7311/207/7316 12 Influenza_A_virus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 14/4622 16/10654 3.530427912199955e-4 7.333637773039432e-4 2.8769108348419126e-4 7040/7314/50848/7046/2280/6233/57530/5590/7048/7311/387/57154/7316/56288 14 Influenza_A_virus R-HSA-418038 Nucleotide-like (purinergic) receptors 14/4622 16/10654 3.530427912199955e-4 7.333637773039432e-4 2.8769108348419126e-4 10161/64805/2840/5028/5029/53829/27334/134/9934/5032/140/5031/5030/2846 14 Influenza_A_virus R-HSA-5619115 Disorders of transmembrane transporters 99/4622 176/10654 3.6425086547792125e-4 7.555233085135518e-4 2.963840401592956e-4 23165/5689/5682/6559/285195/348995/143471/57122/5705/23511/5709/5695/554/23279/5711/10999/23225/5683/5699/6400/5702/9972/8021/55746/5696/5691/6513/7314/5718/5700/122706/5707/79139/23198/10762/553/9861/79902/9883/5698/215/5692/5713/5710/5719/10613/6233/6575/6396/129401/552/4928/5903/55706/7175/6528/5706/5714/4927/5688/5687/5708/8086/6514/5704/7311/11160/5694/81929/5684/5720/9631/5690/5717/9491/1080/79023/23636/10197/1244/7316/10213/53371/3098/9688/7415/5715/5701/5685/682/5686/6520/5716/213/5693/551/5721/6566/8480 99 Influenza_A_virus R-HSA-5205647 Mitophagy 22/4622 29/10654 3.8630636019128576e-4 7.988998395671856e-4 3.1340020812777936e-4 65018/1459/9140/8878/1460/9474/1457/84557/7314/139341/192111/6714/8408/6233/9804/7416/7311/10452/7316/56993/81631/54543 22 Influenza_A_virus R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 22/4622 29/10654 3.8630636019128576e-4 7.988998395671856e-4 3.1340020812777936e-4 2308/84676/4089/4088/3630/847/5443/3066/5105/4303/23410/4287/2908/4852/6648/4087/25942/2309/6720/3065/91584/10891 22 Influenza_A_virus R-HSA-2172127 DAP12 interactions 30/4622 43/10654 4.168708153978214e-4 8.60835154986934e-4 3.3769679673834247e-4 5295/4893/5335/7305/5291/3824/54209/567/2534/3822/2885/3133/3845/3265/5879/5290/5336/7410/3932/6464/3937/10451/6850/9436/22914/695/6654/9402/27040/5296 30 Influenza_A_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 17/4622 21/10654 4.952230162787268e-4 0.0010169485101392476 3.989384638073548e-4 9252/4893/4790/1387/2534/5894/3845/3265/5062/5567/5970/5566/4067/5063/5971/5058/2033 17 Influenza_A_virus R-HSA-5654688 SHC-mediated cascade:FGFR1 17/4622 21/10654 4.952230162787268e-4 0.0010169485101392476 3.989384638073548e-4 4893/2885/3845/3265/8074/2260/2249/2248/2247/2246/2251/6464/6654/2254/26281/2255/27006 17 Influenza_A_virus R-HSA-5654689 PI-3K cascade:FGFR1 17/4622 21/10654 4.952230162787268e-4 0.0010169485101392476 3.989384638073548e-4 5295/2885/5290/8074/2260/2249/2248/2247/2246/2251/5781/2549/2254/26281/10818/2255/27006 17 Influenza_A_virus R-HSA-9609507 Protein localization 92/4622 163/10654 4.953804974283459e-4 0.0010169485101392476 3.989384638073548e-4 6811/9218/26519/7321/131118/10965/10901/5621/26520/3313/10005/8239/10440/50/7917/3417/25813/9512/4358/80273/3421/5192/131474/7314/1891/90639/54332/51608/134266/847/7323/54927/3329/100287932/10469/215/8604/1431/2010/8540/6233/6844/9804/83752/5264/351/51/10245/8266/7416/4714/293/1678/150274/51024/118424/4580/29090/5830/10651/7311/6342/29928/6449/3295/10063/56942/10452/5824/51025/7316/400916/10165/7322/56993/5825/26521/100272147/4843/26517/6901/92609/617/54543/1537/219743/388753/2671/3162/26515/8443/291 92 Influenza_A_virus R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 27/4622 38/10654 5.110517156735331e-4 0.0010475810828615825 4.1095530771092885e-4 759/5908/3313/6175/5898/3181/4282/5062/1072/6627/9049/27250/3185/3458/5478/302/4478/998/6648/6888/3586/829/6647/6950/4507/375/5721 27 Influenza_A_virus R-HSA-180024 DARPP-32 events 20/4622 26/10654 5.26500556865059e-4 0.001076093243417182 4.2214033568281894e-4 5530/5499/5518/5515/84152/5567/5142/5573/5528/5519/801/5566/5577/1020/5141/5516/5575/5576/5534/5144 20 Influenza_A_virus R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 20/4622 26/10654 5.26500556865059e-4 0.001076093243417182 4.2214033568281894e-4 83990/9156/1763/7486/472/4683/672/5888/116028/7517/80010/580/641/10524/5889/79728/10111/675/5932/7156 20 Influenza_A_virus R-HSA-201681 TCF dependent signaling in response to WNT 126/4622 233/10654 5.822930273204151e-4 0.0011883878134218108 4.6619234304100856e-4 27123/9070/5689/857/5682/1459/5526/1452/5929/1460/143471/5705/6657/8452/55366/5709/9978/5695/1457/4609/5711/1387/5683/324/5699/8312/5702/1855/5518/25776/6659/80351/5696/5691/7314/5515/5718/8945/5700/122706/5707/1856/1454/8322/23198/9101/8395/7534/5528/89780/9861/81847/5519/2932/9580/5698/5692/5713/5710/5719/6233/7474/1857/7514/4040/7855/331/8607/4221/123169/7090/6597/864/4041/79577/5706/23401/8658/5714/6934/10524/5688/5687/607/5708/51339/5529/7088/208/57680/5704/7311/5694/5516/5684/8295/5720/7015/1487/1499/5525/139285/207/5690/5717/9491/10197/64750/7316/10213/54361/5715/5701/1455/5685/5686/2033/54894/3065/5527/5716/23072/9736/5693/5721/6259 126 Influenza_A_virus R-HSA-1660514 Synthesis of PIPs at the Golgi membrane 15/4622 18/10654 6.161010273306516e-4 0.0012482742553742766 4.896851796174973e-4 5297/5286/55300/377/55361/55697/30849/7179/93492/200576/5289/22908/5298/375/4952 15 Influenza_A_virus R-HSA-210993 Tie2 Signaling 15/4622 18/10654 6.161010273306516e-4 0.0012482742553742766 4.896851796174973e-4 5295/4893/5291/2885/3845/3265/5290/5781/6464/7010/6654/285/5296/284/9046 15 Influenza_A_virus R-HSA-5654221 Phospholipase C-mediated cascade; FGFR2 15/4622 18/10654 6.161010273306516e-4 0.0012482742553742766 4.896851796174973e-4 5335/2252/8823/8074/2249/2248/2247/2246/2251/2263/8817/2254/26281/2255/27006 15 Influenza_A_virus R-HSA-5654704 SHC-mediated cascade:FGFR3 15/4622 18/10654 6.161010273306516e-4 0.0012482742553742766 4.896851796174973e-4 4893/2885/3845/3265/8823/8074/2249/2247/2246/6464/6654/8817/2254/26281/2261 15 Influenza_A_virus R-HSA-5654710 PI-3K cascade:FGFR3 15/4622 18/10654 6.161010273306516e-4 0.0012482742553742766 4.896851796174973e-4 5295/2885/5290/8823/8074/2249/2247/2246/5781/2549/8817/2254/26281/10818/2261 15 Influenza_A_virus R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 13/4622 15/10654 7.182183782989881e-4 0.0014467857245849935 5.675591917090442e-4 22954/7314/29110/81844/51428/3661/6233/23220/7311/81030/6737/147945/7316 13 Influenza_A_virus R-HSA-5358508 Mismatch Repair 13/4622 15/10654 7.182183782989881e-4 0.0014467857245849935 5.675591917090442e-4 4436/9156/6117/10714/6118/5424/2956/4292/5425/5111/6119/57804/5395 13 Influenza_A_virus R-HSA-5654228 Phospholipase C-mediated cascade; FGFR4 13/4622 15/10654 7.182183782989881e-4 0.0014467857245849935 5.675591917090442e-4 5335/9965/2264/8823/8074/2249/2247/2246/2251/8817/2254/152831/26281 13 Influenza_A_virus R-HSA-844456 The NLRP3 inflammasome 13/4622 15/10654 7.182183782989881e-4 0.0014467857245849935 5.675591917090442e-4 834/4790/7295/29108/10628/5970/5027/4791/351/3326/4210/114548/10910 13 Influenza_A_virus R-HSA-69473 G2/M DNA damage checkpoint 57/4622 95/10654 7.811916900526616e-4 0.0015713755146670805 6.164344877204645e-4 83990/9156/1763/7531/7486/10971/5982/7533/2810/11200/472/4683/165918/84126/8924/672/6117/7334/7465/83695/6118/51588/51720/7534/116028/983/9656/5985/7157/5984/7158/5884/5810/80010/7532/580/11073/891/641/6119/3364/10524/144715/1111/5983/7529/5883/10111/545/7336/29086/7341/995/5932/9025/79184/7156 57 Influenza_A_virus R-HSA-3247509 Chromatin modifying enzymes 145/4622 274/10654 8.151172941347021e-4 0.0016349124493548258 6.413593751327945e-4 9643/9070/1810/4790/79718/64769/51742/10474/9112/10445/5929/79813/7403/54556/84289/9612/6603/9767/27097/5928/1387/56950/3717/6907/23081/23512/1107/79084/57492/23133/22992/6881/10499/1386/55689/3054/51230/55257/8089/55170/23774/84661/8464/9869/196528/2648/23186/55869/84193/2146/1788/51147/6871/23569/86/5970/8850/27154/57459/8289/84159/6602/55929/595/7994/6944/8473/3066/10419/8607/8726/6883/51780/10765/4791/55193/55904/55683/84678/1019/5927/29943/23326/84148/7862/6597/9219/5931/6599/54496/11143/63976/1108/2122/84444/10524/64324/54815/23210/339287/55693/23587/57504/58508/23030/57634/6880/60/6187/53615/10362/4297/10196/8295/8841/55167/11091/8242/5978/6839/25855/284058/6598/117143/79960/9611/2874/10856/29072/10933/2033/6605/3065/23028/23135/10498/80854/9739/10902/3276/9913/8648/64754/10919/54934 145 Influenza_A_virus R-HSA-4839726 Chromatin organization 145/4622 274/10654 8.151172941347021e-4 0.0016349124493548258 6.413593751327945e-4 9643/9070/1810/4790/79718/64769/51742/10474/9112/10445/5929/79813/7403/54556/84289/9612/6603/9767/27097/5928/1387/56950/3717/6907/23081/23512/1107/79084/57492/23133/22992/6881/10499/1386/55689/3054/51230/55257/8089/55170/23774/84661/8464/9869/196528/2648/23186/55869/84193/2146/1788/51147/6871/23569/86/5970/8850/27154/57459/8289/84159/6602/55929/595/7994/6944/8473/3066/10419/8607/8726/6883/51780/10765/4791/55193/55904/55683/84678/1019/5927/29943/23326/84148/7862/6597/9219/5931/6599/54496/11143/63976/1108/2122/84444/10524/64324/54815/23210/339287/55693/23587/57504/58508/23030/57634/6880/60/6187/53615/10362/4297/10196/8295/8841/55167/11091/8242/5978/6839/25855/284058/6598/117143/79960/9611/2874/10856/29072/10933/2033/6605/3065/23028/23135/10498/80854/9739/10902/3276/9913/8648/64754/10919/54934 145 Influenza_A_virus R-HSA-4090294 SUMOylation of intracellular receptors 22/4622 30/10654 8.553741849097814e-4 0.0017043511044976863 6.68599446911599e-4 7068/6613/9759/8856/7067/6612/5914/7421/10062/51588/5465/2099/9063/8554/5241/2908/7329/367/5468/4306/7341/6256 22 Influenza_A_virus R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 22/4622 30/10654 8.553741849097814e-4 0.0017043511044976863 6.68599446911599e-4 4893/817/1741/1739/6196/1740/6197/3845/3265/818/5594/6195/801/5170/2904/27330/816/5595/815/1742/88/1385 22 Influenza_A_virus R-HSA-167169 HIV Transcription Elongation 31/4622 46/10654 8.558329580524862e-4 0.0017043511044976863 6.68599446911599e-4 5431/5435/5433/2965/5439/11198/51497/5438/2068/1025/6829/25920/2963/5434/5436/4331/2962/2071/5432/22916/5440/902/5430/6749/5441/4686/9150/5437/2968/1022/8178 31 Influenza_A_virus R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 31/4622 46/10654 8.558329580524862e-4 0.0017043511044976863 6.68599446911599e-4 5431/5435/5433/2965/5439/11198/51497/5438/2068/1025/6829/25920/2963/5434/5436/4331/2962/2071/5432/22916/5440/902/5430/6749/5441/4686/9150/5437/2968/1022/8178 31 Influenza_A_virus R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 31/4622 46/10654 8.558329580524862e-4 0.0017043511044976863 6.68599446911599e-4 5431/5435/5433/2965/5439/11198/51497/5438/2068/1025/6829/25920/2963/5434/5436/4331/2962/2071/5432/22916/5440/902/5430/6749/5441/4686/9150/5437/2968/1022/8178 31 Influenza_A_virus R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission 112/4622 206/10654 8.854997205145229e-4 0.0017609226305537737 6.907918760021959e-4 2788/5563/4893/5579/5331/2770/51807/817/2550/5578/2898/347688/5582/53632/10381/107/9568/2774/7846/2782/1741/1739/163/6196/1740/8874/6197/3845/3265/814/2773/5879/2787/818/161/79861/5567/4646/5594/51422/10681/112/5573/111/2792/6714/2567/2785/10376/6195/2783/2784/5613/2771/196883/115/1175/801/2791/57576/5170/1173/84617/3838/2904/10382/2036/7277/160/113/10645/55327/5566/84254/5571/27330/23236/347733/3084/816/2786/5577/5562/10383/84790/5564/5565/7280/109/5595/815/54331/5575/59345/3766/51764/94235/114/5330/108/55970/346562/2793/5576/4137/2066/1143/1742/88/1385/4193/2790 112 Influenza_A_virus R-HSA-8856688 Golgi-to-ER retrograde transport 76/4622 133/10654 9.111201940519107e-4 0.0018092983398928567 7.097691703065873e-4 11014/51807/347688/5861/10381/1780/5048/8655/84516/832/55738/10112/636/7846/100302736/2590/11004/10749/81930/54732/51164/79861/55605/23299/377/1315/3796/5870/11316/8729/10376/1314/10540/378/26286/26958/140735/3831/84364/22820/84617/2589/11258/1783/10382/93661/55860/830/7277/10671/9554/1639/8775/9183/1062/347733/51143/10383/84790/84643/7280/829/1778/5321/51014/5050/1781/22930/25782/10121/10972/9276/3799/375/22818/372 76 Influenza_A_virus R-HSA-164938 Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 16/4622 20/10654 9.354437696129977e-4 0.0018497176660805812 7.256252571553218e-4 162/1174/567/163/161/926/3932/1175/8907/940/1173/160/920/8905/164/375 16 Influenza_A_virus R-HSA-2028269 Signaling by Hippo 16/4622 20/10654 9.354437696129977e-4 0.0018497176660805812 7.256252571553218e-4 7531/10413/26524/836/9414/9113/23286/1856/7082/154796/6789/51421/261734/6788/7529/25937 16 Influenza_A_virus R-HSA-69186 Lagging Strand Synthesis 16/4622 20/10654 9.354437696129977e-4 0.0018497176660805812 7.256252571553218e-4 1763/5982/5422/6117/10714/6118/5985/5984/23649/5424/5425/5111/6119/5983/57804/5981 16 Influenza_A_virus R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 51/4622 84/10654 9.933555948197037e-4 0.0019614563863812793 7.694592103792234e-4 7124/1052/4790/79718/9441/892/5469/9612/1387/6907/55588/10499/7040/85441/96764/3952/5465/5970/896/9370/9412/9969/5105/1019/9440/6721/1051/1024/9314/9968/5346/23389/9477/6517/8841/5468/29079/168544/6720/6837/688/9611/2033/9967/7026/6256/10498/112950/8202/8648/10891 51 Influenza_A_virus R-HSA-69190 DNA strand elongation 23/4622 32/10654 0.0010336426803194978 0.0020381275981476133 7.995365398952689e-4 1763/5982/5422/4174/84515/6117/10714/6118/5985/5984/23649/5424/4172/8318/4173/5425/5111/6119/5983/4176/57804/4171/5981 23 Influenza_A_virus R-HSA-75153 Apoptotic execution phase 34/4622 52/10654 0.0011121263590993086 0.0021897924648180754 8.590331105867158e-4 10059/660/836/324/9414/3836/6709/6093/5062/2934/22985/63967/841/100506658/7082/5339/28988/10134/999/5588/5580/839/1828/5747/118/8428/4000/3837/51765/1499/3146/329/4137/7431 34 Influenza_A_virus R-HSA-5693607 Processing of DNA double-strand break ends 58/4622 98/10654 0.0011334385092644703 0.0022286174907900553 8.742637698227687e-4 83990/151987/9156/1763/7486/5982/472/6613/4683/165918/84126/8900/8924/672/6117/7334/83695/7314/6118/51588/51720/63967/5531/116028/890/9656/5985/5984/6233/7158/6047/5884/5810/80010/580/11073/641/6119/3364/10524/144715/1111/7329/7311/5983/1017/5883/10111/51548/545/7336/29086/7316/7341/5932/9025/79184/7156 58 Influenza_A_virus R-HSA-2033519 Activated point mutants of FGFR2 14/4622 17/10654 0.0011968576841683341 0.0023467139445544614 9.205917966364539e-4 2252/8823/8074/2249/2248/2247/2246/2251/2263/8817/2254/26281/2255/27006 14 Influenza_A_virus R-HSA-4655427 SUMOylation of DNA methylation proteins 14/4622 17/10654 0.0011968576841683341 0.0023467139445544614 9.205917966364539e-4 1912/6045/80012/1911/57332/1788/84733/7703/6015/8535/1786/7329/648/7341 14 Influenza_A_virus R-HSA-174411 Polymerase switching on the C-strand of the telomere 12/4622 14/10654 0.001448606518893849 0.0028166229671955506 0.0011049322836449678 5982/5422/10714/5985/5984/23649/5424/5425/5111/5983/57804/5981 12 Influenza_A_virus R-HSA-190322 FGFR4 ligand binding and activation 12/4622 14/10654 0.001448606518893849 0.0028166229671955506 0.0011049322836449678 9965/2264/8823/8074/2249/2247/2246/2251/8817/2254/152831/26281 12 Influenza_A_virus R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 12/4622 14/10654 0.001448606518893849 0.0028166229671955506 0.0011049322836449678 4436/9156/6117/10714/6118/5424/4292/5425/5111/6119/57804/5395 12 Influenza_A_virus R-HSA-69091 Polymerase switching 12/4622 14/10654 0.001448606518893849 0.0028166229671955506 0.0011049322836449678 5982/5422/10714/5985/5984/23649/5424/5425/5111/5983/57804/5981 12 Influenza_A_virus R-HSA-69109 Leading Strand Synthesis 12/4622 14/10654 0.001448606518893849 0.0028166229671955506 0.0011049322836449678 5982/5422/10714/5985/5984/23649/5424/5425/5111/5983/57804/5981 12 Influenza_A_virus R-HSA-8983432 Interleukin-15 signaling 12/4622 14/10654 0.001448606518893849 0.0028166229671955506 0.0011049322836449678 6776/2885/9846/3600/3718/6777/6464/6774/6654/3716/3561/3560 12 Influenza_A_virus R-HSA-1059683 Interleukin-6 signaling 10/4622 11/10654 0.001565703063624868 0.003014948874583424 0.0011827335017377935 9021/3717/3569/3572/7297/5781/6774/6772/3716/867 10 Influenza_A_virus R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 10/4622 11/10654 0.001565703063624868 0.003014948874583424 0.0011827335017377935 64344/3091/1387/2056/405/768/10370/2034/7422/2033 10 Influenza_A_virus R-HSA-2514853 Condensation of Prometaphase Chromosomes 10/4622 11/10654 0.001565703063624868 0.003014948874583424 0.0011827335017377935 1459/1460/1457/10051/983/23397/9133/891/10592/9918 10 Influenza_A_virus R-HSA-400451 Free fatty acids regulate insulin secretion 10/4622 11/10654 0.001565703063624868 0.003014948874583424 0.0011827335017377935 5331/2769/2776/2181/2182/2864/23236/5330/2767/9630 10 Influenza_A_virus R-HSA-4755510 SUMOylation of immune response proteins 10/4622 11/10654 0.001565703063624868 0.003014948874583424 0.0011827335017377935 4792/6612/51588/8517/5970/4791/10210/7329/9641/7341 10 Influenza_A_virus R-HSA-5603041 IRAK4 deficiency (TLR2/4) 10/4622 11/10654 0.001565703063624868 0.003014948874583424 0.0011827335017377935 10333/929/51135/7096/695/23643/7099/4615/114609/7097 10 Influenza_A_virus R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 10/4622 11/10654 0.001565703063624868 0.003014948874583424 0.0011827335017377935 7314/257397/23118/80216/10454/6233/7189/7311/6885/7316 10 Influenza_A_virus R-HSA-193704 p75 NTR receptor-mediated signalling 57/4622 97/10654 0.001576356884939966 0.0030312887553591095 0.0011891434692734703 9639/7984/4790/7531/29/8878/1894/23385/10276/4792/9138/836/23365/3654/8874/3551/7314/5879/8767/6453/9828/5970/5664/396/3066/6233/7410/7409/26574/5663/572/7204/7074/10451/50650/7189/6654/7311/387/4804/57142/8841/5584/10018/57580/11214/23421/4615/7316/4168/23263/50649/9826/4803/3065/5599/10672 57 Influenza_A_virus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 26/4622 38/10654 0.0015863724725203897 0.003046358127175144 0.0011950550291832318 51741/2064/5308/4609/1387/7913/7022/8089/163732/3815/348/2099/3329/10765/7020/4869/10370/7329/29028/1956/7528/7021/7422/1026/7341/2033 26 Influenza_A_virus R-HSA-72306 tRNA processing 62/4622 107/10654 0.001633855780588441 0.0031332378343794792 0.001229137046692048 23165/10785/10557/90353/348995/57122/23511/11260/23279/11102/23225/9972/8021/10799/60487/51367/55746/115708/81605/54913/10775/10940/10248/10762/1478/79042/79902/9883/10556/1653/6396/129401/80746/79897/4928/55039/5903/55706/7175/3028/116461/4927/23536/10898/5901/8086/51002/283989/54517/81929/9631/29894/79023/23636/53371/54931/10978/283742/9688/112858/51493/8480 62 Influenza_A_virus R-HSA-5627123 RHO GTPases activate PAKs 18/4622 24/10654 0.001684205070546118 0.003220955798390524 0.0012635479037432897 2017/4628/5062/5879/4638/4659/4771/801/5500/2316/5063/998/5058/3984/4627/10398/4637/103910 18 Influenza_A_virus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 18/4622 24/10654 0.001684205070546118 0.003220955798390524 0.0012635479037432897 1839/5594/2069/10000/595/7514/2353/5747/208/1956/5595/596/685/2309/207/1027/1950/1385 18 Influenza_A_virus R-HSA-190872 Transport of connexons to the plasma membrane 15/4622 19/10654 0.0017483471759002396 0.0033390564916783265 0.0013098775936784943 51807/347688/2697/10381/7846/79861/10376/84617/10382/2706/7277/347733/10383/84790/7280 15 Influenza_A_virus R-HSA-165159 mTOR signalling 27/4622 40/10654 0.0017686460359369713 0.003373215768403664 0.0013232779273686537 5563/53632/6198/29904/2475/92335/84335/51422/7249/1981/1977/1978/57521/6194/64223/5571/6794/6009/208/1975/5562/5564/5565/7248/7529/207/10542 27 Influenza_A_virus R-HSA-375280 Amine ligand-binding receptors 28/4622 42/10654 0.0019469475692231641 0.0037082189397465715 0.0014546962334221548 3354/1131/3361/1129/1132/1814/1813/146/3357/3352/148/150/4935/11255/147/3350/151/3356/1128/3358/1133/3269/152/3355/3351/1815/154/59340 28 Influenza_A_virus R-HSA-68962 Activation of the pre-replicative complex 23/4622 33/10654 0.002015204140494422 0.003833000528450615 0.0015036467700645815 5422/4174/84515/10926/55388/6117/5001/6118/23649/4172/8318/54107/4173/51053/6119/5427/81620/4176/56655/1017/8317/5426/4171 23 Influenza_A_virus R-HSA-948021 Transport to the Golgi and subsequent modification 100/4622 185/10654 0.0020806349310985746 0.003952075589233434 0.0015503586943683603 6811/6711/11014/10960/51807/10484/347688/5861/10381/1780/9570/90411/8655/84516/832/3998/55738/7846/100302736/9632/3630/6709/54732/51164/79861/10342/4253/2801/4249/377/22872/1315/8615/55014/11316/8729/10376/1314/10540/83696/27095/7109/9334/378/6396/26286/1453/26958/140735/84364/22820/84617/11258/6712/1783/8703/10382/10802/93661/11282/55860/830/7277/10671/9554/11196/1639/10282/8775/4124/347733/51143/23243/5537/9871/10383/84790/7280/829/1778/9919/10113/55291/51014/1604/1781/6484/10121/22870/10972/6708/2683/9276/287/375/84342/64689/10427/22818/372 100 Influenza_A_virus R-HSA-110373 Resolution of AP sites via the multiple-nucleotide patch replacement pathway 19/4622 26/10654 0.002087559245323902 0.0039598477950648775 0.001553407650951586 5982/6117/10714/6118/328/5985/5984/5424/54107/5425/5111/6119/5427/142/5983/56655/57804/5426/5981 19 Influenza_A_virus R-HSA-156711 Polo-like kinase mediated events 13/4622 16/10654 0.0023006459223079596 0.004340489877714612 0.0017027296335285845 5928/7465/993/2305/9133/286826/891/55957/5347/1063/9088/2033/995 13 Influenza_A_virus R-HSA-205043 NRIF signals cell death from the nucleus 13/4622 16/10654 0.0023006459223079596 0.004340489877714612 0.0017027296335285845 8878/23385/7314/5664/6233/5663/7189/7311/4804/23421/7316/4803/5599 13 Influenza_A_virus R-HSA-399956 CRMPs in Sema3A signaling 13/4622 16/10654 0.0023006459223079596 0.004340489877714612 0.0017027296335285845 5361/8829/2534/1808/5362/1400/10371/2932/55558/1020/91584/8851/2242 13 Influenza_A_virus R-HSA-429958 mRNA decay by 3' to 5' exoribonuclease 13/4622 16/10654 0.0023006459223079596 0.004340489877714612 0.0017027296335285845 5393/23404/28960/10767/11340/80349/23016/118460/51010/56915/22894/51013/54512 13 Influenza_A_virus R-HSA-69205 G1/S-Specific Transcription 20/4622 28/10654 0.002496282803544638 0.004703239028780868 0.0018450324026766296 5422/1869/5928/8900/6241/7027/898/5934/983/7298/1719/8318/286826/5111/1874/81620/55957/5933/3065/7083 20 Influenza_B_virus R-HSA-913531 Interferon Signaling 91/578 199/10654 7.775910669701623e-63 8.421311255286858e-60 6.065210322367266e-60 8672/6041/3135/3665/7311/1958/25939/4939/348995/3133/7318/9636/23586/317649/6059/2537/3429/3383/5610/3441/11274/8638/10581/25820/1982/7706/51447/3134/3448/10379/2634/5300/9775/3442/3452/5335/4940/3662/91543/3437/9470/1981/7334/7316/3440/1973/3394/2317/6773/4938/3107/3663/8519/3664/10410/3430/3105/3661/2316/3669/103/8086/2633/7324/5696/4734/9246/3660/1977/3434/5495/5371/1974/3439/3446/54739/3113/6772/9830/51191/3433/3659/7314/4600/4599/3445/6233/5595/3106/684/3716 91 Influenza_B_virus R-HSA-909733 Interferon alpha/beta signaling 55/578 69/10654 1.5412730972315192e-57 8.345993821508676e-55 6.010965079202924e-55 6041/3135/3665/1958/25939/4939/3133/9636/6059/2537/3429/3441/11274/8638/10581/51447/3134/3448/10379/2634/3442/3452/4940/3662/91543/3437/3440/3394/6773/4938/3107/3663/8519/3664/10410/3430/3105/3661/3669/103/5696/3660/3434/3439/3446/54739/6772/3433/3659/4600/4599/3445/3106/684/3716 55 Influenza_B_virus R-HSA-5656169 Termination of translesion DNA synthesis 31/578 32/10654 8.185923042526391e-39 2.955118218352027e-36 2.128339991056862e-36 5982/54107/6119/7311/6118/51455/7318/9636/124739/5427/7706/5983/6117/5429/5985/7316/5981/11201/10714/5424/57804/5984/5425/9246/5111/5426/9100/7314/6233/51426/56655 31 Influenza_B_virus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 33/578 39/10654 1.7111847591152212e-36 4.53697632738457e-34 3.2676283798337624e-034 5982/54107/6119/7311/6118/51455/7318/9636/124739/5427/7706/5983/6117/5429/5985/7316/5981/11201/10714/5424/57804/5984/5425/9246/5111/5426/9100/10459/7314/6233/7415/51426/56655 33 Influenza_B_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 45/578 80/10654 2.0946335768165145e-36 4.53697632738457e-34 3.2676283798337624e-034 8672/6041/7311/4939/348995/7318/9636/23586/317649/6059/5610/11274/8638/25820/1982/7706/5300/9775/5335/4940/9470/1981/7334/7316/1973/2317/4938/3661/2316/8086/7324/4734/9246/1977/3434/5495/1974/6772/51191/7314/4600/4599/6233/5595/3716 45 Influenza_B_virus R-HSA-73893 DNA Damage Bypass 35/578 48/10654 1.862013243942129e-34 3.360933905315543e-32 2.420617217124768e-32 5982/54107/6119/7311/6118/51455/7318/9636/124739/5427/7706/5983/6117/5429/5985/8450/7316/5981/11201/10714/5424/57804/5984/5425/9246/5111/5426/9100/10459/7314/6233/7415/8451/51426/56655 35 Influenza_B_virus R-HSA-6809371 Formation of the cornified envelope 53/578 129/10654 1.1300277540143777e-33 1.74831436799653e-31 1.2591737830445924e-31 147183/342574/3887/3880/3872/112802/374454/125115/3885/54474/3890/8689/3859/25984/3884/3850/3853/3854/3875/3852/3889/286887/3858/121391/3860/3857/192666/140807/3856/3892/3848/319101/51350/338785/8687/3866/353288/3861/8688/3886/9119/3849/3881/390792/196374/162605/3891/3882/3868/3883/3855/144501/3888 53 Influenza_B_virus R-HSA-1169408 ISG15 antiviral mechanism 38/578 72/10654 1.7516116940448142e-29 2.371244330813167e-27 1.7078214016936938e-27 8672/7311/348995/7318/9636/23586/317649/5610/11274/25820/1982/7706/5300/9775/5335/9470/1981/7334/7316/1973/2317/3661/8086/7324/4734/9246/1977/3434/5495/1974/6772/51191/7314/4600/4599/6233/5595/3716 38 Influenza_B_virus R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 22/578 25/10654 1.9304812144024617e-25 2.3230123946642955e-23 1.6730837191488e-23 5982/54107/6119/7311/6118/5427/5983/6117/5985/7316/5981/10714/5424/57804/5984/5425/5111/5426/7314/6233/51426/56655 22 Influenza_B_virus R-HSA-5696400 Dual Incision in GG-NER 27/578 41/10654 6.468589339712303e-25 7.005482254908424e-23 5.045499684975596e-23 5982/54107/6119/7311/6118/5427/5983/6117/5985/2968/8450/7316/5981/10714/2068/5424/57804/5984/5425/5111/5426/1643/7314/6233/8451/51426/56655 27 Influenza_B_virus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 23/578 30/10654 7.277107267503155e-24 7.164642882459924e-22 5.160130607865874e-22 5982/54107/6119/7311/6118/5427/5983/6117/5985/8450/7316/5981/10714/5424/57804/5984/5425/5111/5426/7314/6233/8451/56655 23 Influenza_B_virus R-HSA-6805567 Keratinization 53/578 214/10654 1.6974538686600868e-21 1.5319521164657283e-19 1.1033450146290563e-19 147183/342574/3887/3880/3872/112802/374454/125115/3885/54474/3890/8689/3859/25984/3884/3850/3853/3854/3875/3852/3889/286887/3858/121391/3860/3857/192666/140807/3856/3892/3848/319101/51350/338785/8687/3866/353288/3861/8688/3886/9119/3849/3881/390792/196374/162605/3891/3882/3868/3883/3855/144501/3888 53 Influenza_B_virus R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 18/578 21/10654 1.4681318304159076e-20 1.2230667479541753e-18 8.808790982495446e-19 5982/54107/6119/6118/5427/5983/6117/5985/5981/328/10714/5424/57804/5984/5425/5111/5426/56655 18 Influenza_B_virus R-HSA-5655862 Translesion synthesis by POLK 16/578 17/10654 7.461980351222536e-20 5.387549813582671e-18 3.880229782635719e-18 5982/6119/7311/6118/51455/5983/6117/5985/7316/5981/5984/5111/10459/7314/6233/51426 16 Influenza_B_virus R-HSA-5656121 Translesion synthesis by POLI 16/578 17/10654 7.461980351222536e-20 5.387549813582671e-18 3.880229782635719e-18 5982/6119/7311/6118/51455/5983/6117/5985/7316/5981/11201/5984/5111/10459/7314/6233 16 Influenza_B_virus R-HSA-1268020 Mitochondrial protein import 28/578 64/10654 3.445449748419256e-19 2.332138798461284e-17 1.6796567523543873e-17 80273/56993/9804/26520/54543/26521/25813/90639/100272147/10469/3313/4580/8604/7416/10063/400916/26517/10440/388753/2671/54927/10165/92609/1678/131474/10651/3329/56942 28 Influenza_B_virus R-HSA-110312 Translesion synthesis by REV1 15/578 16/10654 1.3272972476347584e-18 8.455664230520255e-17 6.089952077383009e-17 5982/6119/7311/6118/51455/5983/6117/5985/7316/5981/5984/5111/10459/7314/6233 15 Influenza_B_virus R-HSA-9609507 Protein localization 42/578 163/10654 6.238540571748014e-18 3.753521910668388e-16 2.703367581090806e-16 1891/80273/56993/9804/7311/26520/54543/26521/25813/351/90639/100272147/10469/3313/10005/4580/8604/7416/7323/10063/7316/400916/26517/10440/51/388753/10965/2671/54927/10165/92609/1678/5621/131474/10651/8540/7314/6233/3329/56942/4358/6844 42 Influenza_B_virus R-HSA-3371556 Cellular response to heat stress 31/578 89/10654 1.1785210896512703e-17 6.717570211012241e-16 4.83813921014732e-16 3306/10049/6119/26353/3303/6118/348995/10013/6782/259217/3310/3337/573/3313/3309/3320/6117/3304/3312/3305/116835/9531/8086/9532/22824/9530/3308/51182/7415/5595/3326 31 Influenza_B_virus R-HSA-110373 Resolution of AP sites via the multiple-nucleotide patch replacement pathway 18/578 26/10654 1.3353525217888216e-17 7.230933905486469e-16 5.207874834976404e-16 5982/54107/6119/6118/5427/5983/6117/5985/5981/328/10714/5424/57804/5984/5425/5111/5426/56655 18 Influenza_B_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 29/578 78/10654 1.7242739713500243e-17 8.892327195105126e-16 6.40444617930009e-16 3665/7311/7318/9636/23586/3441/351/7706/3448/5300/3442/3452/7323/64135/7316/3440/1540/5970/3661/9246/3439/3446/57506/51191/7314/3445/6233/79132/4214 29 Influenza_B_virus R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 17/578 24/10654 5.906702550477273e-17 2.907708573712221e-15 2.09419454062376e-15 5982/54107/6119/6118/5427/5983/6117/5985/5981/10714/5424/57804/5984/5425/5111/5426/56655 17 Influenza_B_virus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 26/578 65/10654 9.817943246274483e-17 4.622970667702289e-15 3.329563361780042e-15 5982/54107/6119/7311/6118/5427/5983/6117/5985/2968/8450/7316/5981/10714/2068/5424/57804/5984/5425/5111/5426/7314/6233/8451/51426/56655 26 Influenza_B_virus R-HSA-6782135 Dual incision in TC-NER 26/578 66/10654 1.5388989431490388e-16 6.944281480960037e-15 5.001421565234376e-15 5982/54107/6119/7311/6118/5427/5983/6117/5985/2968/8450/7316/5981/10714/2068/5424/57804/5984/5425/5111/5426/7314/6233/8451/51426/56655 26 Influenza_B_virus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 29/578 84/10654 1.7770412786192406e-16 7.698142818978551e-15 5.544368789292031e-15 5982/54107/6119/7311/6118/5427/60/5983/6117/5985/2968/8450/7334/7316/5981/10714/2068/5424/57804/5984/5425/5111/5426/1643/7314/6233/8451/51426/56655 29 Influenza_B_virus R-HSA-110320 Translesion Synthesis by POLH 15/578 19/10654 2.7602727993991283e-16 1.1497597852881753e-14 8.280818398197385e-15 5982/6119/7311/6118/5983/6117/5429/5985/7316/5981/5984/5111/7314/6233/7415 15 Influenza_B_virus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 26/578 69/10654 5.600894460281848e-16 2.2465810001797194e-14 1.6180361774147562e-14 3306/10049/6119/3303/6118/348995/6782/259217/3310/3337/573/3313/3309/6117/3304/3312/3305/116835/9531/8086/9532/22824/9530/3308/51182/5595 26 Influenza_B_virus R-HSA-180786 Extension of Telomeres 17/578 30/10654 1.5045677938176256e-14 5.819453288230317e-13 4.1912959970633854e-13 5982/54107/6119/6118/5427/5983/6117/5985/5981/10714/5424/57804/5984/5425/5111/5426/56655 17 Influenza_B_virus R-HSA-877300 Interferon gamma signaling 28/578 92/10654 2.3528401242634533e-14 8.7866408778528275e-013 6.328328610087908e-13 3135/3665/4939/3133/3383/8638/7706/3134/10379/2634/4940/3662/3394/4938/3107/3663/3664/3105/3661/2633/3660/5371/3113/6772/9830/3659/3106/3716 28 Influenza_B_virus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 26/578 79/10654 2.4766093646942498e-14 8.940559806546242e-13 6.43918434820505e-13 5982/54107/6119/7311/6118/5427/5983/6117/5985/2968/8450/7316/5981/10714/2068/5424/57804/5984/5425/5111/5426/7314/6233/8451/51426/56655 26 Influenza_B_virus R-HSA-5685942 HDR through Homologous Recombination (HRR) 24/578 67/10654 2.861138689771628e-14 9.99552645491185e-13 7.198994122651193e-13 5982/54107/6119/7311/6118/5427/5983/6117/5429/5985/7316/5981/10714/5424/57804/5984/5425/5111/5426/7314/6233/51426/7517/56655 24 Influenza_B_virus R-HSA-611105 Respiratory electron transport 29/578 100/10654 3.286305478153355e-14 1.1122090102625261e-12 8.010369602998804e-13 51300/9377/7384/4728/4722/4725/51204/6834/4729/7386/4698/4723/1340/6389/4702/1327/4697/4720/27089/7388/2108/4719/6341/55863/51079/4704/7385/2109/4726 29 Influenza_B_virus R-HSA-73933 Resolution of Abasic Sites (AP sites) 18/578 39/10654 2.7423005330593244e-13 8.999731749403784e-12 6.481801259958404e-12 5982/54107/6119/6118/5427/5983/6117/5985/5981/328/10714/5424/57804/5984/5425/5111/5426/56655 18 Influenza_B_virus R-HSA-2262752 Cellular responses to stress 67/578 479/10654 4.1356982908530295e-13 1.3173415438217149e-11 9.48777843195695e-12 3306/10049/7295/10294/6119/7311/26353/3303/3091/6118/5928/348995/10013/6782/5688/7846/259217/3310/3337/529/573/3313/3309/4343/3320/55662/6117/6197/23512/648/7323/7316/3304/3312/112399/10935/526/3305/5052/116835/3301/9531/7157/8453/5970/8535/8086/9532/7324/5696/6045/10963/22824/2289/2936/9588/768/9530/3308/7296/7314/6233/51182/7415/5595/2950/3326 67 Influenza_B_virus R-HSA-5696398 Nucleotide Excision Repair 29/578 111/10654 6.314611863740091e-13 1.9539213281230053e-11 1.4072563582049347e-11 5982/54107/6119/7311/6118/5427/60/5983/6117/5985/2968/8450/7334/7316/5981/10714/2068/5424/57804/5984/5425/5111/5426/1643/7314/6233/8451/51426/56655 29 Influenza_B_virus R-HSA-8953897 Cellular responses to external stimuli 67/578 493/10654 1.6262532421387827e-12 4.892311836767504e-11 3.5235486913006964e-11 3306/10049/7295/10294/6119/7311/26353/3303/3091/6118/5928/348995/10013/6782/5688/7846/259217/3310/3337/529/573/3313/3309/4343/3320/55662/6117/6197/23512/648/7323/7316/3304/3312/112399/10935/526/3305/5052/116835/3301/9531/7157/8453/5970/8535/8086/9532/7324/5696/6045/10963/22824/2289/2936/9588/768/9530/3308/7296/7314/6233/51182/7415/5595/2950/3326 67 Influenza_B_virus R-HSA-69186 Lagging Strand Synthesis 13/578 20/10654 1.6878541959098945e-12 4.940394849109232e-11 3.55817911570194e-11 5982/6119/6118/5983/6117/5985/5981/10714/5424/57804/5984/5425/5111 13 Influenza_B_virus R-HSA-1428517 The citric acid (TCA) cycle and respiratory electron transport 36/578 174/10654 2.0671217972881235e-12 5.891297122271153e-11 4.243039478644043e-11 51300/9377/1737/4967/7384/4728/4722/4725/51204/6834/4729/7386/4698/4723/7416/1340/6389/4702/1327/4697/4720/27089/5160/7388/2108/1743/3029/4719/6341/55863/51079/4704/7385/2109/4726/3939 36 Influenza_B_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 16/578 34/10654 4.06831881385882e-12 1.1297408398484877e-10 8.136637627717639e-11 7311/7318/9636/23586/7706/5300/7323/64135/7316/1540/3661/9246/57506/51191/7314/6233 16 Influenza_B_virus R-HSA-163200 Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 29/578 123/10654 1.0271493242254226e-11 2.7810067953403317e-10 2.0029411822395742e-10 51300/9377/7384/4728/4722/4725/51204/6834/4729/7386/4698/4723/1340/6389/4702/1327/4697/4720/27089/7388/2108/4719/6341/55863/51079/4704/7385/2109/4726 29 Influenza_B_virus R-HSA-933541 TRAF6 mediated IRF7 activation 14/578 29/10654 5.97118423875069e-11 1.577266470869999e-9 1.1359813917623263e-9 3665/23586/3441/7706/3448/3442/3452/64135/3440/3661/3439/3446/57506/3445 14 Influenza_B_virus R-HSA-174411 Polymerase switching on the C-strand of the telomere 10/578 14/10654 1.6829843934037853e-10 4.14243658649159e-9 2.983472333761256e-9 5982/5983/5985/5981/10714/5424/57804/5984/5425/5111 10 Influenza_B_virus R-HSA-69091 Polymerase switching 10/578 14/10654 1.6829843934037853e-10 4.14243658649159e-9 2.983472333761256e-9 5982/5983/5985/5981/10714/5424/57804/5984/5425/5111 10 Influenza_B_virus R-HSA-69109 Leading Strand Synthesis 10/578 14/10654 1.6829843934037853e-10 4.14243658649159e-9 2.983472333761256e-9 5982/5983/5985/5981/10714/5424/57804/5984/5425/5111 10 Influenza_B_virus R-HSA-73894 DNA Repair 48/578 334/10654 4.3287709932916445e-10 1.0417908857188558e-8 7.50320305503885e-9 5982/7158/54107/6119/7311/6118/51455/7318/9636/124739/5427/7706/60/5983/6117/5429/5985/29086/2968/8450/7334/7316/10973/5981/11201/328/10714/2547/2068/7157/5424/57804/5984/5425/9246/5111/5426/9100/1643/10459/7314/7520/6233/7415/8451/51426/7517/56655 48 Influenza_B_virus R-HSA-8949215 Mitochondrial calcium ion transport 12/578 23/10654 4.534647270499363e-10 1.0676136943371328e-8 7.689184502151094e-9 10730/6687/11331/30968/3954/10367/7416/8165/7417/10939/5245/221154 12 Influenza_B_virus R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 27/578 132/10654 1.6317030667412604e-9 3.759860470810181e-8 2.7079327490599646e-8 5982/7158/54107/6119/7311/6118/5427/5983/6117/5429/5985/29086/7334/7316/5981/10714/5424/57804/5984/5425/5111/5426/7314/6233/51426/7517/56655 27 Influenza_B_virus R-HSA-912694 Regulation of IFNA signaling 12/578 26/10654 2.786218920038909e-9 6.286406438337788e-8 4.527605745063228e-8 3441/11274/3448/3442/3452/3440/6773/3439/3446/6772/3445/3716 12 Influenza_B_virus R-HSA-174437 Removal of the Flap Intermediate from the C-strand 8/578 10/10654 2.925518587180922e-9 6.465993122279466e-8 4.656947955104325e-8 6119/6118/6117/10714/5424/57804/5425/5111 8 Influenza_B_virus R-HSA-69190 DNA strand elongation 13/578 32/10654 4.1291326599754386e-9 8.9437013415068e-8 6.441446949561684e-8 5982/6119/6118/5983/6117/5985/5981/10714/5424/57804/5984/5425/5111 13 Influenza_B_virus R-HSA-9613829 Chaperone Mediated Autophagy 11/578 22/10654 4.454974253366795e-9 9.298370659128969e-8 6.696887455328343e-8 1080/7311/3920/10013/3320/7431/7316/3312/7314/6233/3326 11 Influenza_B_virus R-HSA-5693532 DNA Double-Strand Break Repair 30/578 166/10654 4.5187149130059534e-009 9.298370659128969e-8 6.696887455328343e-8 5982/7158/54107/6119/7311/6118/5427/5983/6117/5429/5985/29086/7334/7316/5981/10714/2547/7157/5424/57804/5984/5425/5111/5426/7314/7520/6233/51426/7517/56655 30 Influenza_B_virus R-HSA-5693538 Homology Directed Repair 27/578 138/10654 4.550449168364131e-9 9.298370659128969e-8 6.696887455328343e-8 5982/7158/54107/6119/7311/6118/5427/5983/6117/5429/5985/29086/7334/7316/5981/10714/5424/57804/5984/5425/5111/5426/7314/6233/51426/7517/56655 27 Influenza_B_virus R-HSA-69242 S Phase 29/578 161/10654 8.869396756635803e-9 1.7788067939697361e-7 1.281135087069616e-7 5982/54107/6119/7311/6118/5928/5688/5427/5983/6117/5985/8243/9126/7316/595/5981/10714/5424/57804/5984/5425/7324/5696/5111/5426/4609/7314/6233/56655 29 Influenza_B_virus R-HSA-174414 Processive synthesis on the C-strand of the telomere 8/578 11/10654 1.0216939181197106e-8 2.011808206042994e-7 1.448947738424317e-7 6119/6118/6117/10714/5424/57804/5425/5111 8 Influenza_B_virus R-HSA-69239 Synthesis of DNA 24/578 119/10654 1.7757750972021945e-8 3.434222196910673e-7 2.473401028245914e-7 5982/54107/6119/7311/6118/5688/5427/5983/6117/5985/7316/5981/10714/5424/57804/5984/5425/7324/5696/5111/5426/7314/6233/56655 24 Influenza_B_virus R-HSA-69306 DNA Replication 24/578 127/10654 6.643499935422843e-8 1.2622649877303403e-6 9.091105174789154e-7 5982/54107/6119/7311/6118/5688/5427/5983/6117/5985/7316/5981/10714/5424/57804/5984/5425/7324/5696/5111/5426/7314/6233/56655 24 Influenza_B_virus R-HSA-3371568 Attenuation phase 8/578 14/10654 1.6069558899384444e-7 2.853005293120222e-6 2.0547960559868637e-6 3306/3303/3337/3320/3304/3312/3305/3326 8 Influenza_B_virus R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 8/578 14/10654 1.6069558899384444e-7 2.853005293120222e-6 2.0547960559868637e-6 6119/6118/6117/10714/5424/57804/5425/5111 8 Influenza_B_virus R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 8/578 14/10654 1.6069558899384444e-7 2.853005293120222e-6 2.0547960559868637e-6 6119/6118/6117/10714/5424/57804/5425/5111 8 Influenza_B_virus R-HSA-69166 Removal of the Flap Intermediate 8/578 14/10654 1.6069558899384444e-7 2.853005293120222e-6 2.0547960559868637e-6 6119/6118/6117/10714/5424/57804/5425/5111 8 Influenza_B_virus R-HSA-5696395 Formation of Incision Complex in GG-NER 13/578 43/10654 2.499856051209485e-7 4.366684037838504e-6 3.144980193457094e-6 6119/7311/6118/6117/2968/8450/7334/7316/2068/1643/7314/6233/8451 13 Influenza_B_virus R-HSA-5358508 Mismatch Repair 8/578 15/10654 3.2801387742683284e-7 5.550609832082187e-6 3.997669131139525e-6 6119/6118/6117/10714/5424/57804/5425/5111 8 Influenza_B_virus R-HSA-69183 Processive synthesis on the lagging strand 8/578 15/10654 3.2801387742683284e-7 5.550609832082187e-6 3.997669131139525e-6 6119/6118/6117/10714/5424/57804/5425/5111 8 Influenza_B_virus R-HSA-5689896 Ovarian tumor domain proteases 12/578 38/10654 4.2817476511778367e-7 7.13405031727015e-6 5.138097181413404e-6 7311/23586/7706/324/64135/7316/7157/2099/57506/7314/6233/7415 12 Influenza_B_virus R-HSA-3700989 Transcriptional Regulation by TP53 44/578 365/10654 4.6166924222080273e-7 7.575572565532263e-6 5.456091044427669e-6 5982/9150/9377/355/7295/1025/2810/6119/7311/6118/7161/5928/51204/6834/1386/51499/2821/5300/5983/4343/6117/5985/1340/2968/1327/4697/7316/2068/5052/2744/7157/1457/5984/26013/8626/6873/6341/5371/5111/2936/1643/7296/7314/6233 44 Influenza_B_virus R-HSA-8949664 Processing of SMDT1 8/578 16/10654 6.249275640218609e-7 1.010144107217426e-5 7.275276118463455e-6 10730/6687/11331/30968/10367/10939/5245/221154 8 Influenza_B_virus R-HSA-3371511 HSF1 activation 7/578 12/10654 8.325919490352368e-7 1.3260251188311198e-5 9.550319415404186e-6 6119/6118/10013/3320/6117/7415/3326 7 Influenza_B_virus R-HSA-6799198 Complex I biogenesis 14/578 55/10654 9.016348571763009e-7 1.4151747106114984e-5 1.019239403764514e-5 51300/4728/4722/4725/4729/4698/4723/4702/4720/4719/55863/51079/4704/4726 14 Influenza_B_virus R-HSA-5205685 Pink/Parkin Mediated Mitophagy 9/578 22/10654 1.007265361656927e-6 1.5583834095349314e-5 1.1223814029891473e-5 56993/9804/7311/54543/7416/7316/8878/7314/6233 9 Influenza_B_virus R-HSA-157579 Telomere Maintenance 17/578 82/10654 1.442683441418538e-6 2.2006002352905305e-5 1.5849198370513514e-5 5982/54107/6119/6118/5427/5983/6117/5985/5981/10714/5424/57804/5984/5425/5111/5426/56655 17 Influenza_B_virus R-HSA-5205647 Mitophagy 10/578 29/10654 1.6020832172745717e-6 2.4098001726505015e-5 1.7355901520474526e-5 56993/9804/7311/54543/7416/7316/1457/8878/7314/6233 10 Influenza_B_virus R-HSA-73884 Base Excision Repair 18/578 92/10654 1.7329783003451289e-6 2.570980135991472e-5 1.8516754442043845e-5 5982/54107/6119/6118/5427/5983/6117/5985/5981/328/10714/5424/57804/5984/5425/5111/5426/56655 18 Influenza_B_virus R-HSA-3371571 HSF1-dependent transactivation 9/578 24/10654 2.4005319047636885e-6 3.513210882241993e-5 2.5302903861022665e-5 3306/26353/3303/3337/3320/3304/3312/3305/3326 9 Influenza_B_virus R-HSA-5628897 TP53 Regulates Metabolic Genes 17/578 86/10654 2.8930534084673727e-6 4.177569121826886e-5 3.0087755448060677e-5 9377/7295/2810/51204/6834/2821/4343/1340/1327/4697/5052/2744/7157/8626/6341/2936/7296 17 Influenza_B_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 8/578 19/10654 3.1729823289219443e-6 4.4627790418473584e-5 3.2141898916352165e-5 7311/1956/5290/3320/5335/7316/7314/6233 8 Influenza_B_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 8/578 19/10654 3.1729823289219443e-6 4.4627790418473584e-5 3.2141898916352165e-5 7311/1956/5290/3320/5335/7316/7314/6233 8 Influenza_B_virus R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 13/578 55/10654 5.431965286430809e-6 7.542074878467392e-5 5.4319652864308086e-5 3306/10294/3303/7846/3337/3320/3304/3312/3305/3301/10963/2289/3326 13 Influenza_B_virus R-HSA-9612973 Autophagy 20/578 119/10654 5.536622353551056e-6 7.590078492273156e-5 5.466538526290916e-5 56993/1080/9804/7311/54543/3920/10013/64419/55626/3320/7416/7431/7316/3312/1457/55054/8878/7314/6233/3326 20 Influenza_B_virus R-HSA-6807070 PTEN Regulation 22/578 140/10654 5.9357003771285455e-6 8.035454385537768e-5 5.7873078677003314e-5 10014/7311/1958/5928/5688/1386/4343/23512/648/7316/7157/1457/8535/10273/5696/4734/6045/5371/7314/6233/2122/5595 22 Influenza_B_virus R-HSA-1236977 Endosomal/Vacuolar pathway 6/578 11/10654 9.083919506484792e-6 1.2145536821633371e-4 8.747478043281653e-5 3135/3133/3134/3107/3105/3106 6 Influenza_B_virus R-HSA-1236394 Signaling by ERBB4 13/578 58/10654 1.0164227813514495e-5 1.342421795370268e-4 9.66841182261135e-5 7311/51741/23385/1956/5290/348/3084/7316/4734/10413/2099/7314/6233 13 Influenza_B_virus R-HSA-8863795 Downregulation of ERBB2 signaling 9/578 29/10654 1.4398367286472994e-5 1.8787267194277413e-4 1.353099576319149e-4 7311/9101/1956/3320/3084/7316/10273/7314/6233 9 Influenza_B_virus R-HSA-5689877 Josephin domain DUBs 6/578 12/10654 1.733524706393433e-5 2.2087144200283386e-4 1.590763848219856e-4 7311/4287/7316/7314/6233/7415 6 Influenza_B_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 6/578 12/10654 1.733524706393433e-5 2.2087144200283386e-4 1.590763848219856e-4 3665/7311/7316/3661/7314/6233 6 Influenza_B_virus R-HSA-73886 Chromosome Maintenance 18/578 110/10654 2.3600424364954826e-5 2.9720069287495437e-4 2.1405036051935772e-4 5982/54107/6119/6118/5928/5427/5983/6117/5985/5981/10714/5424/57804/5984/5425/5111/5426/56655 18 Influenza_B_virus R-HSA-8949613 Cristae formation 9/578 31/10654 2.628758257769958e-5 3.272350796741224e-4 2.3568177483454799e-4 25813/3313/55735/4580/10989/54927/84303/10651/139322 9 Influenza_B_virus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 6/578 13/10654 3.072008909204678e-5 3.7381861220996246e-4 2.6923224148085945e-4 7311/9101/3084/7316/7314/6233 6 Influenza_B_virus R-HSA-209560 NF-kB is activated and signals survival 6/578 13/10654 3.072008909204678e-5 3.7381861220996246e-4 2.6923224148085945e-4 7311/7316/5970/8878/7314/6233 6 Influenza_B_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 11/578 47/10654 3.174573234709509e-5 3.820069792433776e-4 2.7512968034149076e-4 10014/7311/3091/10013/79885/7316/55294/9759/4609/7314/6233 11 Influenza_B_virus R-HSA-1643713 Signaling by EGFR in Cancer 8/578 25/10654 3.396675329118664e-5 3.998477588516862e-4 2.879789952948432e-4 7311/1956/5290/3320/5335/7316/7314/6233 8 Influenza_B_virus R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 8/578 25/10654 3.396675329118664e-5 3.998477588516862e-4 2.879789952948432e-4 3135/3133/3134/3309/3107/3105/6890/3106 8 Influenza_B_virus R-HSA-918233 TRAF3-dependent IRF activation pathway 6/578 14/10654 5.130128055612218e-5 5.974116864761325e-4 4.302688046642506e-4 3665/23586/7706/64135/3661/57506 6 Influenza_B_virus R-HSA-1227986 Signaling by ERBB2 11/578 50/10654 5.869629016735495e-5 6.762561941621852e-4 4.8705432266528577e-4 7311/9101/1956/5290/3320/3084/5335/7316/10273/7314/6233 11 Influenza_B_virus R-HSA-5688426 Deubiquitination 33/578 297/10654 6.808859147909568e-5 7.762099428616909e-4 5.590431721441541e-4 4089/1080/9804/7311/3091/9101/5688/23586/11274/4287/7347/27005/7706/60/7416/324/29086/64135/7316/1540/7417/7157/5696/63891/4738/2099/57506/9100/1643/4609/7314/6233/7415 33 Influenza_B_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 6/578 15/10654 8.159535009710371e-5 9.204975432829512e-4 6.629622195389676e-4 3665/7311/7334/7316/7314/6233 6 Influenza_B_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 15/578 92/10654 1.163368478745316e-4 0.0012988949097744095 9.354921787848933e-4 5982/6119/7311/6118/5300/5983/6117/5985/7316/7157/1457/5984/6873/7314/6233 15 Influenza_B_virus R-HSA-1295596 Spry regulation of FGF signaling 6/578 16/10654 1.2459333835761603e-4 0.0013493458544129816 9.718280391894051e-4 7311/7316/673/7314/6233/5595 6 Influenza_B_virus R-HSA-193639 p75NTR signals via NF-kB 6/578 16/10654 1.2459333835761603e-4 0.0013493458544129816 9.718280391894051e-4 7311/7316/5970/8878/7314/6233 6 Influenza_B_virus R-HSA-205043 NRIF signals cell death from the nucleus 6/578 16/10654 1.2459333835761603e-4 0.0013493458544129816 9.718280391894051e-4 7311/23385/7316/8878/7314/6233 6 Influenza_B_virus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 11/578 56/10654 1.7399951260438696e-4 0.0018657571500054562 0.0013437586121922954 3315/7311/3303/5688/1981/7316/3304/3312/5696/7314/6233 11 Influenza_B_virus R-HSA-933542 TRAF6 mediated NF-kB activation 7/578 24/10654 2.0531226005218408e-4 0.0021799331140834838 0.0015700349298108194 23586/351/7706/64135/5970/57506/4214 7 Influenza_B_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 8/578 32/10654 2.357795814057618e-4 0.0024176594495236635 0.001741250573064134 4089/7514/7311/7316/10273/4738/7314/6233 8 Influenza_B_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 11/578 58/10654 2.410962331934955e-4 0.0024176594495236635 0.001741250573064134 10014/7311/10013/23385/79885/7316/55294/9759/4609/7314/6233 11 Influenza_B_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 11/578 58/10654 2.410962331934955e-4 0.0024176594495236635 0.001741250573064134 10014/7311/10013/23385/79885/7316/55294/9759/4609/7314/6233 11 Influenza_B_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 11/578 58/10654 2.410962331934955e-4 0.0024176594495236635 0.001741250573064134 10014/7311/10013/23385/79885/7316/55294/9759/4609/7314/6233 11 Influenza_B_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 11/578 58/10654 2.410962331934955e-4 0.0024176594495236635 0.001741250573064134 10014/7311/10013/23385/79885/7316/55294/9759/4609/7314/6233 11 Influenza_B_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 11/578 58/10654 2.410962331934955e-4 0.0024176594495236635 0.001741250573064134 10014/7311/10013/23385/79885/7316/55294/9759/4609/7314/6233 11 Influenza_B_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 14/578 88/10654 2.5440395890162645e-4 0.0025277017200959766 0.0018205053939749417 3315/7514/7311/3303/5688/1981/7316/3304/3312/5696/167227/7314/6233/1994 14 Influenza_B_virus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 6/578 18/10654 2.631024772644793e-4 0.0025903634807039194 0.0018656357478753988 3665/7311/7316/3661/7314/6233 6 Influenza_B_virus R-HSA-5687128 MAPK6/MAPK4 signaling 14/578 89/10654 2.8718628246885845e-4 0.002802006701925889 0.0020180657687000865 3315/7514/7311/5688/3337/4343/5596/7316/998/5597/5696/4609/7314/6233 14 Influenza_B_virus R-HSA-6804760 Regulation of TP53 Activity through Methylation 6/578 19/10654 3.670361135204917e-4 0.00354344715884118 0.0025520672058135926 7311/7316/7157/26013/7314/6233 6 Influenza_B_virus R-HSA-70263 Gluconeogenesis 8/578 34/10654 3.697225567396615e-4 0.00354344715884118 0.0025520672058135926 2023/226/2821/2597/8604/6576/5230/10165 8 Influenza_B_virus R-HSA-8943724 Regulation of PTEN gene transcription 11/578 61/10654 3.8192545830860344e-4 0.0036282918539317327 0.0026131741884272866 10014/1958/5928/1386/23512/648/7157/8535/6045/2122/5595 11 Influenza_B_virus R-HSA-5633007 Regulation of TP53 Activity 20/578 160/10654 4.044159265930689e-4 0.0038085430304373355 0.0027429949803703803 5982/6119/7311/6118/7161/5928/5300/5983/6117/5985/7316/7157/1457/5984/26013/8626/6873/5371/7314/6233 20 Influenza_B_virus R-HSA-209543 p75NTR recruits signalling complexes 5/578 13/10654 4.1292682272071776e-4 0.0038551702500563565 0.00277657691139793 7311/7316/8878/7314/6233 5 Influenza_B_virus R-HSA-453279 Mitotic G1-G1/S phases 19/578 149/10654 4.35242546929989e-4 0.004028783575428873 0.0029016169795332597 7153/54107/6119/7311/6118/5928/5688/5427/6117/7316/595/1859/5696/5111/5426/4609/7314/6233/56655 19 Influenza_B_virus R-HSA-9615710 Microautophagy 8/578 35/10654 4.5682261306828056e-4 0.004192702457228372 0.003019674899942872 1080/7311/10013/7431/7316/3312/7314/6233 8 Influenza_B_virus R-HSA-1236974 ER-Phagosome pathway 13/578 83/10654 4.897865871981846e-4 0.004457469528870873 0.0032103658656687734 3135/7311/3133/5688/3134/7316/3107/3105/5696/6890/7314/6233/3106 13 Influenza_B_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 6/578 20/10654 5.005024272503654e-4 0.004462624616293958 0.003214078671015039 7311/7323/7334/7316/7314/6233 6 Influenza_B_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 11/578 63/10654 5.098310502845751e-4 0.004462624616293958 0.003214078671015039 3665/7311/51082/7316/1499/2547/5970/3661/7314/7520/6233 11 Influenza_B_virus R-HSA-9033241 Peroxisomal protein import 11/578 63/10654 5.098310502845751e-4 0.004462624616293958 0.003214078671015039 1891/7311/10005/7323/7316/51/10965/8540/7314/6233/4358 11 Influenza_B_virus R-HSA-1980143 Signaling by NOTCH1 12/578 73/10654 5.099674426375616e-4 0.004462624616293958 0.003214078671015039 10014/7311/3091/10013/23385/79885/7316/55294/9759/4609/7314/6233 12 Influenza_B_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 14/578 94/10654 5.109560964177754e-4 0.004462624616293958 0.003214078671015039 3665/7311/1386/351/6197/7323/7334/7316/5970/3661/1849/7314/6233/5595 14 Influenza_B_virus R-HSA-1632852 Macroautophagy 14/578 95/10654 5.70128610691463e-4 0.004939594283030836 0.0035576025307147295 56993/9804/7311/54543/64419/55626/7416/7316/3312/1457/55054/8878/7314/6233 14 Japanese_encephalitis_virus R-HSA-909733 Interferon alpha/beta signaling 32/106 69/10654 1.7574415942985964e-47 8.910228883093883e-45 5.623813101755508e-45 3449/3440/3455/3448/10379/9021/3443/3660/3665/3434/3456/3444/3446/3452/6773/6772/3454/7297/8651/3663/5781/5777/3659/3662/4599/3445/3664/3451/3661/3441/5770/3716 32 Japanese_encephalitis_virus R-HSA-912694 Regulation of IFNA signaling 22/106 26/10654 1.2720732510224532e-41 3.224705691341919e-39 2.035317201635925e-39 3449/3440/3455/3448/9021/3443/3456/3444/3446/3452/6773/6772/3454/7297/8651/5781/5777/3445/3451/3441/5770/3716 22 Japanese_encephalitis_virus R-HSA-913531 Interferon Signaling 37/106 199/10654 5.65871817941487e-38 9.56323372321113e-36 6.035966058042528e-36 3449/3717/3440/3455/3448/10379/9021/3459/3443/3660/3665/3434/3456/3444/3446/3452/6773/6772/3458/3460/3454/7297/8651/3663/5781/5777/3659/3662/4599/3445/3664/3451/3661/3441/5770/3716/23586 37 Japanese_encephalitis_virus R-HSA-449147 Signaling by Interleukins 46/106 461/10654 4.754089226819692e-35 6.0258080949939596e-33 3.8032713814557536e-33 3717/59307/51135/3605/3557/7124/11213/3559/3627/3586/3654/2353/9021/3576/29110/282618/3563/4615/7189/53832/3554/3553/163702/6773/6772/3552/6352/3458/3320/7297/8651/3588/5781/3725/5777/4790/3662/3569/54472/5970/6597/3146/3656/3556/3716/1386 46 Japanese_encephalitis_virus R-HSA-933541 TRAF6 mediated IRF7 activation 20/106 29/10654 1.2673785921280584e-34 1.2851218924178512e-32 8.111222989619573e-33 3449/64135/3440/3448/3443/3665/29110/7189/3456/3444/3446/3452/57506/1387/3445/2033/3451/3661/3441/23586 20 Japanese_encephalitis_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 23/106 78/10654 1.58046634827272e-28 1.3354940642904485e-26 8.429153857454507e-27 3449/64135/3440/3448/3443/3665/29110/7189/3456/3444/3446/3452/57506/4790/1387/3445/2033/5970/3146/3451/3661/3441/23586 23 Japanese_encephalitis_virus R-HSA-168898 Toll-like Receptor Cascades 24/106 155/10654 1.8524810977659753e-22 1.3417255950962136e-20 8.468485018358744e-21 54106/7097/59307/7099/51135/11213/3654/2353/3665/29110/4615/7189/929/7098/8651/5781/3725/51284/4790/5970/3146/3661/3656/1386 24 Japanese_encephalitis_virus R-HSA-877312 Regulation of IFNG signaling 11/106 14/10654 1.9732920662134752e-20 1.207400383796255e-18 7.620673033822517e-19 3717/9021/3459/6772/3458/3460/8651/5781/5777/5770/3716 11 Japanese_encephalitis_virus R-HSA-877300 Interferon gamma signaling 19/106 92/10654 2.1433142907625828e-20 1.207400383796255e-18 7.620673033822517e-19 3717/10379/9021/3459/3660/3665/6772/3458/3460/8651/3663/5781/5777/3659/3662/3664/3661/5770/3716 19 Japanese_encephalitis_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 21/106 129/10654 3.5147192561890846e-20 1.781962662887866e-18 1.124710161980507e-18 7097/59307/7099/51135/11213/3654/2353/3665/29110/4615/7189/929/8651/5781/3725/4790/5970/3146/3661/3656/1386 21 Japanese_encephalitis_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 17/106 95/10654 3.303959813687028e-17 1.3959230212827693e-15 8.810559503165408e-16 7097/59307/7099/51135/11213/3654/2353/4615/7189/929/8651/3725/4790/5970/3146/3656/1386 17 Japanese_encephalitis_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 17/106 95/10654 3.303959813687028e-17 1.3959230212827693e-15 8.810559503165408e-16 7097/59307/7099/51135/11213/3654/2353/4615/7189/929/8651/3725/4790/5970/3146/3656/1386 17 Japanese_encephalitis_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 17/106 98/10654 5.75059687090067e-17 2.0825375811047427e-15 1.314422141920153e-15 7097/59307/7099/51135/11213/3654/2353/4615/7189/929/8651/3725/4790/5970/3146/3656/1386 17 Japanese_encephalitis_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 17/106 98/10654 5.75059687090067e-17 2.0825375811047427e-15 1.314422141920153e-15 7097/59307/7099/51135/11213/3654/2353/4615/7189/929/8651/3725/4790/5970/3146/3656/1386 17 Japanese_encephalitis_virus R-HSA-446652 Interleukin-1 family signaling 19/106 140/10654 8.786919653367847e-17 2.969978842838332e-15 1.8745428593851407e-15 59307/51135/3557/11213/3654/29110/4615/7189/3554/3553/3552/5781/5777/4790/54472/5970/3146/3656/3556 19 Japanese_encephalitis_virus R-HSA-6783783 Interleukin-10 signaling 13/106 47/10654 4.670556516472278e-16 1.479982596157153e-14 9.341113032944557e-15 3557/7124/3627/3586/3576/3554/3553/3552/6352/7297/3588/3569/3716 13 Japanese_encephalitis_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 16/106 93/10654 5.818395242368237e-16 1.6388479932670535e-14 1.03438137642102e-14 54106/7099/51135/3654/2353/3665/4615/7189/929/3725/51284/4790/5970/3146/3656/1386 16 Japanese_encephalitis_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 16/106 93/10654 5.818395242368237e-16 1.6388479932670535e-14 1.03438137642102e-14 54106/7099/51135/3654/2353/3665/4615/7189/929/3725/51284/4790/5970/3146/3656/1386 16 Japanese_encephalitis_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 16/106 97/10654 1.1734037086272284e-15 3.1311351593368675e-14 1.976258877687964e-14 54106/7099/51135/3654/2353/3665/4615/7189/929/3725/51284/4790/5970/3146/3656/1386 16 Japanese_encephalitis_virus R-HSA-918233 TRAF3-dependent IRF activation pathway 9/106 14/10654 1.2989261473766412e-15 3.292777783599786e-14 2.0782818358026256e-14 64135/3665/29110/3456/57506/1387/2033/3661/23586 9 Japanese_encephalitis_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 16/106 108/10654 6.8938557814243345e-15 1.664373752943875e-13 1.0504923095503749e-13 3717/3605/7124/3586/2353/9021/3576/3553/6772/3552/3320/7297/8651/3662/3569/3716 16 Japanese_encephalitis_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 15/106 92/10654 1.1653134545012053e-14 2.685517824691414e-13 1.6950013883653895e-13 54106/7099/51135/3654/2353/4615/7189/929/3725/51284/4790/5970/3146/3656/1386 15 Japanese_encephalitis_virus R-HSA-8854691 Interleukin-20 family signaling 10/106 25/10654 1.779801307219309e-14 3.9233011424356074e-13 2.476245297000778e-13 3717/282618/53832/163702/6773/6772/7297/3588/5781/3716 10 Japanese_encephalitis_virus R-HSA-166166 MyD88-independent TLR4 cascade 15/106 99/10654 3.6193294066202875e-14 7.340000036625943e-13 4.632741640473968e-13 7099/3654/2353/3665/29110/7189/929/5781/3725/4790/5970/3146/3661/3656/1386 15 Japanese_encephalitis_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 15/106 99/10654 3.6193294066202875e-14 7.340000036625943e-13 4.632741640473968e-13 7099/3654/2353/3665/29110/7189/929/5781/3725/4790/5970/3146/3661/3656/1386 15 Japanese_encephalitis_virus R-HSA-9020702 Interleukin-1 signaling 15/106 103/10654 6.64377024230364e-14 1.2955351972492097e-12 8.176947990527556e-13 51135/3557/11213/3654/4615/7189/3554/3553/3552/4790/54472/5970/3146/3656/3556 15 Japanese_encephalitis_virus R-HSA-1059683 Interleukin-6 signaling 7/106 11/10654 2.5227715417303493e-12 4.737204339471434e-11 2.989951456865599e-11 3717/9021/6772/7297/5781/3569/3716 7 Japanese_encephalitis_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 13/106 94/10654 6.812061115392862e-12 1.2334696376800647e-10 7.785212703306129e-11 3654/2353/3665/29110/7189/7098/3725/4790/5970/3146/3661/3656/1386 13 Japanese_encephalitis_virus R-HSA-5260271 Diseases of Immune System 8/106 24/10654 4.73635909568104e-11 7.787012212413498e-10 4.914879502903983e-10 7097/7099/51135/4615/929/7098/4790/5970 8 Japanese_encephalitis_virus R-HSA-5602358 Diseases associated with the TLR signaling cascade 8/106 24/10654 4.73635909568104e-11 7.787012212413498e-10 4.914879502903983e-10 7097/7099/51135/4615/929/7098/4790/5970 8 Japanese_encephalitis_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 7/106 15/10654 4.7612895184382334e-11 7.787012212413498e-10 4.914879502903983e-10 54106/51135/3654/3665/4615/7189/51284 7 Japanese_encephalitis_virus R-HSA-983231 Factors involved in megakaryocyte development and platelet production 15/106 168/10654 9.251550965490115e-11 1.4657926060948402e-9 9.251550965490116e-10 3449/3717/3440/60/3448/3443/3660/3456/3444/3446/3452/3659/3445/3451/3441 15 Japanese_encephalitis_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 11/106 85/10654 6.450431278633407e-10 9.343910452191821e-9 5.897537169036258e-9 51135/3654/2353/4615/7189/3725/4790/5970/3146/3656/1386 11 Japanese_encephalitis_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 11/106 85/10654 6.450431278633407e-10 9.343910452191821e-9 5.897537169036258e-9 51135/3654/2353/4615/7189/3725/4790/5970/3146/3656/1386 11 Japanese_encephalitis_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 11/106 85/10654 6.450431278633407e-10 9.343910452191821e-9 5.897537169036258e-9 51135/3654/2353/4615/7189/3725/4790/5970/3146/3656/1386 11 Japanese_encephalitis_virus R-HSA-6783589 Interleukin-6 family signaling 7/106 24/10654 2.379413669458972e-9 3.260439811934321e-8 2.057871281694246e-8 3717/9021/6772/7297/5781/3569/3716 7 Japanese_encephalitis_virus R-HSA-933542 TRAF6 mediated NF-kB activation 7/106 24/10654 2.379413669458972e-9 3.260439811934321e-8 2.057871281694246e-8 64135/7189/57506/4790/5970/3146/23586 7 Japanese_encephalitis_virus R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 8/106 38/10654 2.8072866695909013e-9 3.7455114249541766e-8 2.3640308796554956e-8 6599/6601/8289/2033/6598/6605/6597/6602 8 Japanese_encephalitis_virus R-HSA-193639 p75NTR signals via NF-kB 6/106 16/10654 6.212399252262004e-9 8.076119027940605e-8 5.097353232625235e-8 3654/4615/7189/4804/4790/5970 6 Japanese_encephalitis_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 9/106 63/10654 1.025740612339184e-8 1.3001262261399157e-7 8.205924898713472e-8 3665/29110/4615/7098/4790/1387/2033/5970/3661 9 Japanese_encephalitis_virus R-HSA-8878171 Transcriptional regulation by RUNX1 15/106 239/10654 1.2490645939752686e-8 1.544574997915759e-7 9.748796831026487e-8 6599/6601/8861/3559/9021/8850/8289/3458/5781/1387/2033/6598/6605/6597/6602 15 Japanese_encephalitis_virus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 6/106 18/10654 1.4170759952828179e-8 1.7106131657342588e-7 1.0796769487869089e-7 7099/3665/29110/929/5781/3661 6 Japanese_encephalitis_virus R-HSA-110056 MAPK3 (ERK1) activation 5/106 10/10654 2.1477557826350696e-8 2.5323539111534425e-7 1.5983298847516797e-7 3717/7297/5781/3569/3716 5 Japanese_encephalitis_virus R-HSA-5603041 IRAK4 deficiency (TLR2/4) 5/106 11/10654 3.906454026998454e-8 4.5013004356550367e-7 2.8410574741806936e-7 7097/7099/51135/4615/929 5 Japanese_encephalitis_virus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 6/106 21/10654 4.043106777741517e-8 4.555233636255443e-7 2.875098153060634e-7 29110/4615/7098/4790/5970/3661 6 Japanese_encephalitis_virus R-HSA-3247509 Chromatin modifying enzymes 15/106 274/10654 7.731519772862207e-8 8.340171329449231e-7 5.264013462374268e-7 3717/6599/6601/60/8850/8289/4790/1387/2033/5970/6598/6605/6597/6602/1386 15 Japanese_encephalitis_virus R-HSA-4839726 Chromatin organization 15/106 274/10654 7.731519772862207e-8 8.340171329449231e-7 5.264013462374268e-7 3717/6599/6601/60/8850/8289/4790/1387/2033/5970/6598/6605/6597/6602/1386 15 Japanese_encephalitis_virus R-HSA-982772 Growth hormone receptor signaling 6/106 24/10654 9.78859334677603e-8 1.0339201722532182e-6 6.525728897850687e-7 3717/9021/6772/8651/5777/5770 6 Japanese_encephalitis_virus R-HSA-209560 NF-kB is activated and signals survival 5/106 13/10654 1.0711088656166803e-7 1.1082697854441977e-6 6.994996673415056e-7 3654/7189/4804/4790/5970 5 Japanese_encephalitis_virus R-HSA-448424 Interleukin-17 signaling 8/106 72/10654 5.197737078374082e-7 5.270505397471319e-6 3.3265517301594125e-6 3605/3654/2353/7189/3725/4790/3656/1386 8 Japanese_encephalitis_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 6/106 33/10654 7.4908383316751e-7 7.4467745767828944e-6 4.700133855168691e-6 3654/7189/4790/5970/3146/3656 6 Japanese_encephalitis_virus R-HSA-3214858 RMTs methylate histone arginines 8/106 79/10654 1.0697273835103878e-6 1.0429841989226281e-5 6.582937744679309e-6 3717/6599/6601/8289/6598/6605/6597/6602 8 Japanese_encephalitis_virus R-HSA-5602498 MyD88 deficiency (TLR2/4) 4/106 10/10654 1.8567309022384807e-6 1.776155787613037e-5 1.1210450730496486e-5 7097/7099/4615/929 4 Japanese_encephalitis_virus R-HSA-9018519 Estrogen-dependent gene expression 10/106 150/10654 2.273195350095612e-6 2.134277856478658e-5 1.347078725982585e-5 2962/2353/8850/3320/3725/2957/1387/5430/2033/1386 10 Japanese_encephalitis_virus R-HSA-112409 RAF-independent MAPK1/3 activation 5/106 23/10654 2.5872019074185484e-6 2.3849297582930985e-5 1.5052811097707918e-5 3717/7297/5781/3569/3716 5 Japanese_encephalitis_virus R-HSA-193692 Regulated proteolysis of p75NTR 4/106 11/10654 2.895397394791909e-6 2.575379787999119e-5 1.625486256725282e-5 7189/4804/4790/5970 4 Japanese_encephalitis_virus R-HSA-9020956 Interleukin-27 signaling 4/106 11/10654 2.895397394791909e-6 2.575379787999119e-5 1.625486256725282e-5 3717/6772/7297/3716 4 Japanese_encephalitis_virus R-HSA-450294 MAP kinase activation 7/106 64/10654 3.0821716106451393e-6 2.6942431148225612e-5 1.7005084748386976e-5 3654/2353/7189/3725/4790/3656/1386 7 Japanese_encephalitis_virus R-HSA-449836 Other interleukin signaling 5/106 24/10654 3.2422850584582233e-6 2.7861669909124053e-5 1.7585274893332735e-5 282618/163702/7297/3588/3716 5 Japanese_encephalitis_virus R-HSA-8984722 Interleukin-35 Signalling 4/106 12/10654 4.30987661209511e-6 3.572937157855684e-5 2.255108265313252e-5 3717/6772/7297/3716 4 Japanese_encephalitis_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 4/106 12/10654 4.30987661209511e-6 3.572937157855684e-5 2.255108265313252e-5 3665/29110/7098/3661 4 Japanese_encephalitis_virus R-HSA-451927 Interleukin-2 family signaling 6/106 44/10654 4.369272264044426e-6 3.572937157855684e-5 2.255108265313252e-5 3717/3559/3563/6772/5777/3716 6 Japanese_encephalitis_virus R-HSA-912526 Interleukin receptor SHC signaling 5/106 27/10654 6.013804016258539e-6 4.8396803749890146e-5 3.0546306114329084e-5 3717/3559/3563/5777/3716 5 Japanese_encephalitis_virus R-HSA-209543 p75NTR recruits signalling complexes 4/106 13/10654 6.177772490109953e-6 4.893954144508978e-5 3.0888862450549765e-5 3654/4615/7189/4804 4 Japanese_encephalitis_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 6/106 48/10654 7.3548221188321364e-6 5.736761252689066e-5 3.620835504655821e-5 3717/3559/3563/5781/5777/3716 6 Japanese_encephalitis_virus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 4/106 16/10654 1.5367420091186213e-5 1.1804972706411227e-4 7.450870347241801e-5 7099/7189/929/3656 4 Japanese_encephalitis_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 5/106 34/10654 1.961227957654317e-5 1.4651984854343705e-4 9.247801091498985e-5 64135/29110/57506/3661/23586 5 Japanese_encephalitis_virus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 4/106 17/10654 1.994233988597015e-5 1.4651984854343705e-4 9.247801091498985e-5 4615/7098/4790/5970 4 Japanese_encephalitis_virus R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 4/106 17/10654 1.994233988597015e-5 1.4651984854343705e-4 9.247801091498985e-5 7099/7189/929/3656 4 Japanese_encephalitis_virus R-HSA-447115 Interleukin-12 family signaling 6/106 57/10654 2.022956488765403e-5 1.4651984854343705e-4 9.247801091498985e-5 3717/3586/6772/3458/7297/3716 6 Japanese_encephalitis_virus R-HSA-5686938 Regulation of TLR by endogenous ligand 4/106 19/10654 3.1983399246876657e-5 2.28388498847415e-4 1.4415053181690888e-4 7097/7099/929/3146 4 Japanese_encephalitis_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 4/106 21/10654 4.86351310286388e-5 3.3778097851397084e-4 2.1319509492006048e-4 4790/1387/2033/5970 4 Japanese_encephalitis_virus R-HSA-9008059 Interleukin-37 signaling 4/106 21/10654 4.86351310286388e-5 3.3778097851397084e-4 2.1319509492006048e-4 59307/29110/5781/5777 4 Japanese_encephalitis_virus R-HSA-1433557 Signaling by SCF-KIT 5/106 43/10654 6.319339888081125e-5 4.3296017881853114e-4 2.7326875191702166e-4 3717/6772/8651/5781/5777 5 Japanese_encephalitis_virus R-HSA-8939211 ESR-mediated signaling 10/106 223/10654 7.271628471820228e-5 4.915620846950474e-4 3.1025614813099637e-4 2962/2353/8850/3320/3725/2957/1387/5430/2033/1386 10 Japanese_encephalitis_virus R-HSA-1169408 ISG15 antiviral mechanism 6/106 72/10654 7.720636181470404e-5 5.150477031586178e-4 3.2507941816717497e-4 3434/6772/4599/3661/3716/23586 6 Japanese_encephalitis_virus R-HSA-167161 HIV Transcription Initiation 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 2962/2960/2959/2957/5430 5 Japanese_encephalitis_virus R-HSA-167162 RNA Polymerase II HIV Promoter Escape 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 2962/2960/2959/2957/5430 5 Japanese_encephalitis_virus R-HSA-73776 RNA Polymerase II Promoter Escape 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 2962/2960/2959/2957/5430 5 Japanese_encephalitis_virus R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 2962/2960/2959/2957/5430 5 Japanese_encephalitis_virus R-HSA-75953 RNA Polymerase II Transcription Initiation 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 2962/2960/2959/2957/5430 5 Japanese_encephalitis_virus R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 2962/2960/2959/2957/5430 5 Japanese_encephalitis_virus R-HSA-9020591 Interleukin-12 signaling 5/106 47/10654 9.757429676126682e-5 5.960261259995455e-4 3.761900598024745e-4 3717/3586/3458/7297/3716 5 Japanese_encephalitis_virus R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 4/106 25/10654 9.969580213758398e-5 6.017353771875604e-4 3.7979353195270087e-4 8850/6772/1387/2033 4 Japanese_encephalitis_virus R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 7/106 110/10654 1.0861024442425021e-4 6.363276845042179e-4 4.0162694090996e-4 2353/3576/3552/3725/4790/3569/5970 7 Japanese_encephalitis_virus R-HSA-450341 Activation of the AP-1 family of transcription factors 3/106 10/10654 1.0919232455989537e-4 6.363276845042179e-4 4.0162694090996e-4 2353/3725/1386 3 Japanese_encephalitis_virus R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 3/106 10/10654 1.0919232455989537e-4 6.363276845042179e-4 4.0162694090996e-4 8850/1387/2033 3 Japanese_encephalitis_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 6/106 80/10654 1.3925798827435726e-4 8.023159097170356e-4 5.063926846340264e-4 3434/6772/4599/3661/3716/23586 6 Japanese_encephalitis_virus R-HSA-2586552 Signaling by Leptin 3/106 11/10654 1.4905367224680926e-4 8.491035036981157e-4 5.359233159435838e-4 3717/9021/5781 3 Japanese_encephalitis_virus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 3/106 12/10654 1.9730160412504728e-4 0.0011114657032377665 7.015168146668349e-4 64135/57506/23586 3 Japanese_encephalitis_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 5/106 55/10654 2.07769021329253e-4 0.0011575702616915522 7.306163387402302e-4 3654/7189/4790/5970/3656 5 Japanese_encephalitis_virus R-HSA-1679131 Trafficking and processing of endosomal TLR 3/106 13/10654 2.5463875361552893e-4 0.0014032809574247083 8.85700012575753e-4 54106/7098/51284 3 Japanese_encephalitis_virus R-HSA-3371568 Attenuation phase 3/106 14/10654 3.2174493346276634e-4 0.0017353689496342822 0.001095301901149843 3320/1387/2033 3 Japanese_encephalitis_virus R-HSA-8941856 RUNX3 regulates NOTCH signaling 3/106 14/10654 3.2174493346276634e-4 0.0017353689496342822 0.001095301901149843 8850/1387/2033 3 Japanese_encephalitis_virus R-HSA-193704 p75 NTR receptor-mediated signalling 6/106 97/10654 3.99603484037572e-4 0.0021326206990215685 0.0013460327883370847 3654/4615/7189/4804/4790/5970 6 Japanese_encephalitis_virus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 5/106 65/10654 4.560048609537547e-4 0.002408275671912017 0.0015200162031791824 2962/2353/3725/5430/1386 5 Japanese_encephalitis_virus R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 3/106 16/10654 4.878722431679952e-4 0.0025500126524347793 0.001609475441378953 8850/1387/2033 3 Japanese_encephalitis_virus R-HSA-73887 Death Receptor Signalling 7/106 141/10654 5.016063080590139e-4 0.0025950448794481635 0.0016378981487641271 7124/3654/4615/7189/4804/4790/5970 7 Japanese_encephalitis_virus R-HSA-5689896 Ovarian tumor domain proteases 4/106 38/10654 5.267483469995212e-4 0.0026975900194823963 0.001702620919594412 64135/7189/57506/23586 4 Japanese_encephalitis_virus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 6/106 103/10654 5.510941231285975e-4 0.0027940472042619897 0.0017635011940115124 51135/3654/4615/7189/5781/3556 6 Japanese_encephalitis_virus R-HSA-6788467 IL-6-type cytokine receptor ligand interactions 3/106 17/10654 5.881429367284286e-4 0.0029523610784288447 0.0018634231658722488 3717/7297/3716 3 Japanese_encephalitis_virus R-HSA-2559583 Cellular Senescence 8/106 195/10654 7.114679108685945e-4 0.00353641402755272 0.0022320561909602967 2353/3576/3456/3552/3725/4790/3569/5970 8 Japanese_encephalitis_virus R-HSA-9006931 Signaling by Nuclear Receptors 10/106 299/10654 7.6950202359387e-4 0.003769040710386929 0.0023788817106978645 2962/2353/8850/3320/3725/2957/1387/5430/2033/1386 10 Japanese_encephalitis_virus R-HSA-167172 Transcription of the HIV genome 5/106 73/10654 7.787349645964273e-4 0.003769040710386929 0.0023788817106978645 2962/2960/2959/2957/5430 5 Japanese_encephalitis_virus R-HSA-199418 Negative regulation of the PI3K/AKT network 6/106 110/10654 7.805705613227368e-4 0.003769040710386929 0.0023788817106978645 51135/3654/4615/7189/5781/3556 6 Japanese_encephalitis_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 13/106 473/10654 8.062232399371029e-4 0.003856180968378407 0.002433881479055405 3717/54106/2962/60/6772/4916/3320/8651/533/5781/5777/5430/5770 13 Japanese_encephalitis_virus R-HSA-6807505 RNA polymerase II transcribes snRNA genes 5/106 74/10654 8.286371808802624e-4 0.003926346268283113 0.00247816726992228 2962/2960/2959/2957/5430 5 Japanese_encephalitis_virus R-HSA-2262752 Cellular responses to stress 13/106 479/10654 9.057175580625575e-4 0.004251840758682562 0.002683607579444615 2353/2908/3576/3456/3552/3320/533/3725/4790/1387/3569/2033/5970 13 Japanese_encephalitis_virus R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 3/106 20/10654 9.648384221695954e-4 0.004487826422385182 0.0028325531660024815 8850/1387/2033 3 Lassa_virus R-HSA-416476 G alpha (q) signalling events 163/901 217/10654 7.228760210432104e-132 8.782943655675006e-129 7.167886440238992e-129 1910/5295/2788/10316/10681/5367/257313/146/5028/6915/8503/64106/1908/5021/2847/2864/6865/51764/3356/84109/2922/5031/8997/57121/115557/2149/2150/8620/94235/6870/23620/128674/3060/885/3357/2793/5330/3814/4922/9170/10800/2797/10911/5731/301/351/2865/1956/8477/6866/84432/5032/5290/2642/23236/54331/7200/2863/4923/5296/10874/2769/10161/3827/347148/2798/2846/1909/2828/6197/56923/5737/3845/94233/1128/338557/2693/3062/56413/84634/147/2785/5331/552/1907/2925/3265/2783/624/3061/2641/2796/2784/59345/55970/148/5029/6375/2829/23566/2782/222545/57105/1133/9630/29933/6288/2358/2867/2151/6869/387129/7204/5020/7201/3269/4935/6863/1902/4295/4828/2776/1131/551/185/129521/8111/1241/2791/9002/887/4829/2786/2767/2915/2792/2147/60675/2869/680/886/5724/84539/6846/10886/5594/2911/2840/5332/2862/27334/846/1906/3358/553/2790/2520/183/2787/2837/5580/623/594857 163 Lassa_virus R-HSA-6798695 Neutrophil degranulation 167/901 480/10654 4.023328882762973e-63 2.444172296278506e-60 1.9947241092435373e-60 55004/10097/2717/5908/410/3916/3685/25801/10694/10092/127829/8773/1667/55860/4353/2512/719/93100/58485/2548/9798/1727/47/8804/1432/411/11010/8826/80331/2760/5864/3920/29108/81567/23385/6836/9342/10890/55754/79980/7276/4257/302/10383/2171/23317/5476/8904/5036/10577/5284/5005/5836/10396/9145/968/9218/55313/201294/326624/388697/6036/83858/2588/23593/2517/3608/51806/124583/11240/4332/2357/3614/2720/10576/1511/80142/5657/3579/1509/175/5660/2040/2212/25798/2444/5873/4718/8635/6278/4126/8673/2896/1088/8895/9545/10493/5707/5611/2358/10043/8655/23200/84061/387263/5834/527/6386/203068/4125/5547/10970/2990/567/8876/401258/272/5663/150372/1650/566/2665/7879/1075/23197/51552/374395/10075/53916/79888/383/2799/5878/387921/5724/154664/2683/1991/671/56729/9588/353189/54918/5594/29952/4069/10487/6317/967/114790/2519/6037/5879/353/54472/7415/51316/1778/8836/718/3074/3326/5580/684/6709/4680/10857 167 Lassa_virus R-HSA-500792 GPCR ligand binding 158/901 468/10654 1.7224369608470748e-57 6.975869691430653e-55 5.693107428484016e-55 1910/2788/10316/10681/5367/257313/146/5028/6915/64106/1908/719/5021/2847/2864/6865/51764/3356/84109/2922/5031/57121/2149/2150/8620/94235/6870/23620/128674/3060/885/3357/2793/3814/4922/9170/10800/2797/2535/10911/5731/301/351/2865/8477/187/6866/7855/84432/5032/2642/54331/7200/2863/4923/7481/10874/10161/3827/347148/2798/2846/1909/1081/2828/56923/5737/94233/1128/338557/2693/3062/56413/84634/147/2357/2785/552/1907/2925/2783/624/3061/2641/3579/2796/2784/5660/59345/55970/148/5029/6375/2829/23566/2782/222545/57105/1133/29933/6288/2358/2867/2151/6869/387129/5020/7201/3269/4935/6863/1902/4295/4828/1131/551/185/129521/8111/1241/2791/9002/887/6010/4829/8323/2786/186/2915/8322/2792/2147/60675/680/886/1889/5724/7976/84539/6846/10886/2911/2840/2862/27334/846/1906/3358/553/7474/2790/183/718/2787/2837/623/594857/170589 158 Lassa_virus R-HSA-373076 Class A/1 (Rhodopsin-like receptors) 128/901 335/10654 2.7821310580854844e-53 8.450723088934659e-51 6.896756465043492e-51 1910/10316/5367/257313/146/5028/6915/64106/1908/719/5021/2847/2864/6865/3356/84109/2922/5031/57121/2149/2150/8620/6870/23620/128674/3060/885/3357/3814/4922/9170/10800/2797/10911/5731/301/351/2865/8477/187/6866/84432/5032/7200/2863/4923/10874/10161/3827/347148/2798/2846/1909/1081/2828/56923/5737/94233/1128/338557/2693/3062/56413/84634/147/2357/552/1907/2925/624/3061/3579/2796/5660/148/5029/6375/2829/23566/57105/1133/29933/6288/2358/2867/2151/6869/387129/5020/7201/3269/4935/6863/1902/4295/4828/1131/551/185/129521/8111/1241/9002/887/6010/4829/186/2147/60675/680/886/1889/5724/84539/6846/10886/2840/2862/27334/1906/3358/553/183/718/2837/623/594857/170589 128 Lassa_virus R-HSA-375276 Peptide ligand-binding receptors 81/901 201/10654 1.1565510704333923e-35 2.8104191011531434e-33 2.2936233859963274e-33 1910/10316/5367/257313/64106/1908/719/5021/2847/6865/84109/2922/2149/2150/8620/6870/23620/128674/3060/885/3814/4922/10911/301/351/187/6866/84432/7200/4923/10874/3827/347148/1909/56923/2693/3062/84634/2357/552/1907/2925/624/3061/3579/5660/6375/2829/6288/2358/2151/6869/387129/5020/7201/6863/4295/4828/551/185/129521/9002/887/4829/186/2147/60675/680/886/1889/84539/6846/10886/2862/1906/553/183/718/2837/623/594857 81 Lassa_virus R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 35/901 43/10654 1.1495746900706853e-30 2.3278887473931376e-28 1.8998234351694484e-28 2788/10681/359/51764/112/4645/94235/114/2793/108/54331/22841/5573/113/196883/2785/115/2783/8766/2784/59345/55970/2782/5567/111/107/551/2791/2786/109/2792/5568/2790/2787/5566 35 Lassa_virus R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 29/901 32/10654 1.9756437553438342e-28 3.4291530896325125e-26 2.7985810789983336e-26 2788/10681/409/51764/2149/94235/2793/54331/2769/2785/2783/2784/59345/2768/55970/2782/9630/2151/2776/2791/9002/2786/2767/2792/2147/5594/2790/2787/10672 29 Lassa_virus R-HSA-111885 Opioid Signalling 48/901 91/10654 5.251847197427945e-28 7.976242931093692e-26 6.509526394706743e-26 2788/10681/51764/112/94235/114/2793/5330/2780/108/23236/54331/2779/5573/2775/113/808/196883/2785/5331/115/2783/2784/59345/55970/801/2782/816/5567/2770/111/107/2781/2791/2786/109/5499/2792/2771/2773/5594/5332/5568/2790/805/2787/5580/5566 48 Lassa_virus R-HSA-163359 Glucagon signaling in metabolic regulation 29/901 33/10654 1.5005998177239173e-27 2.0258097539272883e-25 1.6532924307554738e-25 2788/51764/112/94235/114/108/2642/54331/5573/113/196883/2785/115/2783/2641/2784/59345/55970/2782/5567/111/107/2791/2786/109/5568/2790/2787/5566 29 Lassa_virus R-HSA-4086398 Ca2+ pathway 39/901 62/10654 6.035074911064159e-27 7.332616016942953e-25 5.984253227602567e-25 2788/10681/51764/5145/94235/2793/5330/2780/5148/2535/5158/7855/23236/54331/7481/4343/2775/808/3845/2785/5331/1499/2783/2784/59345/55970/801/2782/2791/8323/2786/8322/2792/7976/7474/2790/805/2787/5592 39 Lassa_virus R-HSA-392518 Signal amplification 28/901 32/10654 1.605190855301105e-26 1.773006262900766e-24 1.4469758714771685e-24 2788/10681/5028/6915/51764/1432/94235/2793/54331/2769/2785/2783/2784/59345/55970/2782/9630/2770/2776/2791/2786/2767/2792/2771/2773/2790/2787/10672 28 Lassa_virus R-HSA-445717 Aquaporin-mediated transport 35/901 52/10654 8.270237002001992e-26 8.373614964527017e-24 6.833827417443752e-24 2788/10681/359/51764/112/4645/94235/114/2793/108/54331/22841/5573/113/196883/2785/115/2783/8766/2784/59345/55970/2782/5567/111/107/551/2791/2786/109/2792/5568/2790/2787/5566 35 Lassa_virus R-HSA-428930 Thromboxane signalling through TP receptor 23/901 23/10654 1.633883995264872e-25 1.5270531186513998e-23 1.2462499785745017e-23 2788/10681/6915/51764/94235/2793/54331/2769/2785/2783/2784/59345/55970/2782/9630/2776/2791/2786/2767/2792/2790/2787/10672 23 Lassa_virus R-HSA-163685 Integration of energy metabolism 48/901 108/10654 9.222067659315794e-24 8.003437290049064e-22 6.531720101560511e-22 2788/10681/2864/51764/47/112/8826/94235/114/2793/4082/5330/108/2642/23236/54331/2769/5573/113/196883/2785/5331/115/2783/2641/2784/59345/55970/2782/9630/3630/5567/2770/111/107/2776/1131/2791/2786/2767/109/2792/2771/5568/2790/2787/6844/5566 48 Lassa_virus R-HSA-418592 ADP signalling through P2Y purinoceptor 1 23/901 25/10654 4.1564721372690483e-23 3.366742431187929e-21 2.7476468444262765e-21 2788/10681/5028/51764/1432/94235/2793/54331/2769/2785/2783/2784/59345/55970/2782/9630/2776/2791/2786/2767/2792/2790/2787 23 Lassa_virus R-HSA-422356 Regulation of insulin secretion 40/901 78/10654 6.322999619212945e-23 4.80152783583983e-21 3.918595816643812e-21 2788/10681/2864/51764/112/8826/94235/114/2793/4082/5330/23236/54331/2769/5573/2785/5331/2783/2641/2784/59345/55970/2782/9630/3630/5567/2770/111/2776/1131/2791/2786/2767/2792/2771/5568/2790/2787/6844/5566 40 Lassa_virus R-HSA-202040 G-protein activation 24/901 28/10654 1.9862473765839827e-22 1.41958268385267e-20 1.158541813462608e-20 2788/10681/51764/94235/2793/2780/54331/2779/2775/2785/2783/2784/59345/55970/2782/2770/2781/2791/2786/2792/2771/2773/2790/2787 24 Lassa_virus R-HSA-418217 G beta:gamma signalling through PLC beta 20/901 20/10654 2.882313400078954e-22 1.945561545053294e-20 1.5878007151312133e-20 2788/10681/51764/94235/2793/5330/23236/54331/2785/5331/2783/2784/59345/55970/2782/2791/2786/2792/2790/2787 20 Lassa_virus R-HSA-418597 G alpha (z) signalling events 31/901 48/10654 3.575480628342672e-22 2.286425770229656e-20 1.865984904099057e-20 2788/10681/51764/112/94235/114/2793/108/54331/113/196883/2785/115/2783/2784/59345/55970/2782/2770/111/107/2781/2791/2786/109/2792/2771/2773/2790/2787/5580 31 Lassa_virus R-HSA-500657 Presynaptic function of Kainate receptors 20/901 21/10654 5.575273392099341e-21 3.3869785857003494e-19 2.7641618607145155e-19 2788/10681/51764/94235/2793/5330/23236/54331/2785/5331/2783/2784/59345/55970/2782/2791/2786/2792/2790/2787 20 Lassa_virus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 36/901 72/10654 2.830167437655085e-20 1.6374540175004419e-18 1.3363497374792432e-18 4012/6517/5898/8773/79058/4644/55763/53632/10890/10383/7846/60/6810/808/71/54536/5872/8766/60412/801/10640/9847/4218/4627/11336/51552/149371/4641/7529/208/6814/5879/805/55770/23265/6844 36 Lassa_virus R-HSA-9009391 Extra-nuclear estrogen signaling 37/901 77/10654 4.8439131937619557e-20 2.675161150191262e-18 2.183237429915676e-18 5295/2788/3315/10681/7514/8503/51764/94235/2793/1956/857/5290/54331/5296/808/3845/2100/4846/2785/3265/2783/2784/59345/55970/801/2782/2770/2791/2786/2792/2771/2773/5594/208/2790/805/2787 37 Lassa_virus R-HSA-392170 ADP signalling through P2Y purinoceptor 12 20/901 22/10654 5.64895927719503e-20 2.9841241399095487e-18 2.4353865625252715e-18 2788/10681/51764/94235/2793/54331/2785/2783/2784/59345/55970/2782/2770/2791/2786/2792/2771/2773/2790/2787 20 Lassa_virus R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 27/901 42/10654 2.1586826050101948e-19 1.0928330687864111e-17 8.918767604910541e-18 2788/10681/10694/51764/94235/2793/2780/54331/2779/2775/2785/10576/2783/2784/59345/55970/2782/2770/8787/2781/2791/2786/2792/2771/2773/2790/2787 27 Lassa_virus R-HSA-76002 Platelet activation, signaling and aggregation 70/901 262/10654 6.76419899280407e-19 3.287400710502778e-17 2.682894926830078e-17 5295/2788/10681/409/5908/1191/5028/6915/8503/51764/1432/2149/94235/3920/2793/351/5290/54331/5296/5005/81/135228/6810/2769/10447/3827/808/5874/2785/2783/51706/2784/5660/59345/2768/55970/51097/1445/801/2782/9630/2151/998/2770/2776/2316/5894/2791/9002/2786/813/2767/3959/2792/2147/2771/2773/5594/94121/10487/967/6814/5879/2790/805/2787/6647/139322/5580/10672 70 Lassa_virus R-HSA-112043 PLC beta mediated events 30/901 54/10654 8.081189579271918e-19 3.776402053390531e-17 3.081975944807347e-17 112/114/5330/2780/108/23236/2779/5573/2775/113/808/196883/5331/115/801/816/5567/2770/111/107/2781/109/2771/2773/5594/5332/5568/805/5580/5566 30 Lassa_virus R-HSA-418594 G alpha (i) signalling events 91/901 406/10654 1.1491092098607912e-18 5.1709914443735605e-17 4.220120373056005e-17 2788/10316/10681/5367/7804/719/2847/51764/112/5145/57121/94235/114/2793/5330/2780/9170/5148/7276/301/351/5158/187/108/23236/54331/6121/10874/2779/5573/348/3827/2775/113/808/56923/196883/2357/2785/5331/1259/115/2783/624/3579/2784/388531/5660/59345/55970/801/23566/2782/2986/816/6288/2358/5567/2770/111/107/1902/8787/2781/129521/2791/6010/1258/2786/186/109/5499/2792/84539/2771/2773/3000/5594/2840/5332/846/5568/2790/805/183/718/2787/5957/5580/5566/623 91 Lassa_virus R-HSA-112040 G-protein mediated events 30/901 55/10654 1.6368230573339318e-18 7.102642909502597e-17 5.796568872212647e-17 112/114/5330/2780/108/23236/2779/5573/2775/113/808/196883/5331/115/801/816/5567/2770/111/107/2781/109/2771/2773/5594/5332/5568/805/5580/5566 30 Lassa_virus R-HSA-451326 Activation of kainate receptors upon glutamate binding 23/901 32/10654 2.1823754862767292e-18 9.143400744228365e-17 7.462060646361813e-17 2788/10681/51764/94235/2793/5330/23236/54331/808/2785/5331/2783/2784/59345/55970/801/2782/2791/2786/2792/2790/805/2787 23 Lassa_virus R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 26/901 42/10654 4.076031912368623e-18 1.6507929245092924e-16 1.347235811035524e-16 2788/10681/51764/112/8826/94235/114/2793/54331/5573/2785/2783/2641/2784/59345/55970/2782/5567/111/2791/2786/2792/5568/2790/2787/5566 26 Lassa_virus R-HSA-977444 GABA B receptor activation 25/901 39/10654 5.287935479674604e-18 2.0077630024389512e-16 1.6385642177149597e-16 2788/112/94235/114/2793/108/54331/113/196883/2785/115/2783/2784/55970/2782/2770/111/107/2786/109/2792/2771/2773/2790/2787 25 Lassa_virus R-HSA-991365 Activation of GABAB receptors 25/901 39/10654 5.287935479674604e-18 2.0077630024389512e-16 1.6385642177149597e-16 2788/112/94235/114/2793/108/54331/113/196883/2785/115/2783/2784/55970/2782/2770/111/107/2786/109/2792/2771/2773/2790/2787 25 Lassa_virus R-HSA-8964616 G beta:gamma signalling through CDC42 18/901 20/10654 6.7520504024729106e-18 2.4859821936377536e-16 2.0288457668674586e-16 2788/10681/51764/94235/2793/54331/2785/2783/2784/59345/55970/2782/998/2791/2786/2792/2790/2787 18 Lassa_virus R-HSA-8964315 G beta:gamma signalling through BTK 17/901 18/10654 8.355406741344548e-18 2.985829173745184e-16 2.436778065122775e-16 2788/10681/51764/94235/2793/54331/2785/2783/2784/59345/55970/2782/2791/2786/2792/2790/2787 17 Lassa_virus R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 21/901 28/10654 1.5895600362242737e-17 5.518044125749979e-16 4.503355049994785e-16 2788/10681/51764/112/94235/2793/54331/2785/2783/2784/59345/55970/2782/2770/111/2791/2786/2792/2771/2790/2787 21 Lassa_virus R-HSA-397795 G-protein beta:gamma signalling 22/901 32/10654 5.595438010059467e-17 1.8884603283950702e-15 1.5411995922444498e-15 2788/10681/51764/94235/2793/5330/23236/54331/2785/5331/2783/2784/59345/55970/2782/998/2791/2786/2792/208/2790/2787 22 Lassa_virus R-HSA-392851 Prostacyclin signalling through prostacyclin receptor 17/901 19/10654 7.314727292066834e-17 2.4019982864489737e-15 1.960305294203971e-15 2788/10681/51764/94235/2793/54331/2785/2783/2784/59345/55970/2782/2791/2786/2792/2790/2787 17 Lassa_virus R-HSA-390466 Chaperonin-mediated protein folding 36/901 95/10654 1.9128881831478064e-15 6.116208269801539e-14 4.9915253975768244e-14 2788/10681/10694/51764/94235/2793/26270/2780/10383/7846/60/54331/2779/2775/2785/55294/10576/2783/2629/2784/59345/55970/7411/2782/7157/2770/8787/2781/2791/2786/2792/2771/2773/2790/2787/10564 36 Lassa_virus R-HSA-163615 PKA activation 16/901 19/10654 4.59439934643373e-15 1.4313321040812774e-13 1.1681306840325435e-13 112/114/108/5573/113/808/196883/115/801/5567/111/107/109/5568/805/5566 16 Lassa_virus R-HSA-3858494 Beta-catenin independent WNT signaling 45/901 146/10654 4.813199171064964e-15 1.462009248210983e-13 1.1931667418797886e-13 2788/10681/409/51764/5145/94235/2793/5330/2780/5148/2535/5158/7855/23236/54331/160/7481/4343/2775/808/3845/2785/5331/7316/1499/2783/2784/59345/55970/801/2782/5707/2791/8323/2786/8322/2792/7976/1212/5879/7474/2790/805/2787/5592 45 Lassa_virus R-HSA-156588 Glucuronidation 18/901 25/10654 1.1344640192066301e-14 3.2818423412763225e-13 2.6783586618863295e-13 54600/54658/54659/7366/7367/54579/7365/54575/10720/54490/7364/54577/574537/79799/54657/54578/7363/54576 18 Lassa_virus R-HSA-392451 G beta:gamma signalling through PI3Kgamma 18/901 25/10654 1.1344640192066301e-14 3.2818423412763225e-13 2.6783586618863295e-13 2788/10681/51764/94235/2793/54331/2785/2783/2784/59345/55970/2782/2791/2786/2792/208/2790/2787 18 Lassa_virus R-HSA-391251 Protein folding 36/901 101/10654 1.7871659397045307e-14 5.049782829630244e-13 4.121200282011427e-13 2788/10681/10694/51764/94235/2793/26270/2780/10383/7846/60/54331/2779/2775/2785/55294/10576/2783/2629/2784/59345/55970/7411/2782/7157/2770/8787/2781/2791/2786/2792/2771/2773/2790/2787/10564 36 Lassa_virus R-HSA-1268020 Mitochondrial protein import 28/901 64/10654 3.550683440422648e-14 9.804728136621629e-13 8.00177942793812e-13 80273/56993/9804/26520/54543/26521/25813/90639/100272147/10469/4580/8604/7416/10063/400916/26517/10440/6901/388753/2671/54927/10165/92609/1678/131474/10651/3329/56942 28 Lassa_virus R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission 53/901 206/10654 7.550482998882906e-14 2.0386304096983845e-12 1.663755552034549e-12 2788/10681/51764/112/94235/114/2793/53632/5330/10383/7846/108/23236/54331/160/5573/3084/113/808/6197/3845/196883/2785/5331/115/3265/2783/2890/2784/59345/55970/801/2891/2782/816/5567/2770/111/107/2791/2786/109/2792/4646/2771/2773/5594/5879/5568/2790/805/2787/5566 53 Lassa_virus R-HSA-111931 PKA-mediated phosphorylation of CREB 16/901 21/10654 8.197524168039821e-14 2.1652156226453006e-12 1.7670635620808953e-12 112/114/108/5573/113/808/196883/115/801/5567/111/107/109/5568/805/5566 16 Lassa_virus R-HSA-977443 GABA receptor activation 25/901 56/10654 4.80893608146253e-13 1.2431611359525476e-11 1.0145616548124757e-11 2788/112/94235/114/2793/108/54331/113/196883/2785/115/2783/2784/55970/2782/2770/111/107/2786/109/2792/2771/2773/2790/2787 25 Lassa_virus R-HSA-420092 Glucagon-type ligand receptors 19/901 33/10654 9.029835785473286e-13 2.2856771831979255e-11 1.865373971472771e-11 2788/10681/51764/94235/2793/2642/54331/2785/2783/2641/2784/59345/55970/2782/2791/2786/2792/2790/2787 19 Lassa_virus R-HSA-170670 Adenylate cyclase inhibitory pathway 12/901 14/10654 9.697116960236574e-12 2.404489205446416e-10 1.9623381689673157e-10 112/114/108/113/196883/115/2770/111/107/109/2771/2773 12 Lassa_virus R-HSA-418346 Platelet homeostasis 30/901 88/10654 1.0325353110788001e-11 2.5090608059214844e-10 2.0476805537604838e-10 2788/10681/7804/51764/1432/94235/2793/54331/808/10846/4846/2785/2783/2784/59345/55970/801/2782/50940/5138/2977/2791/2786/8654/491/2792/2790/805/2787/5592 30 Lassa_virus R-HSA-164378 PKA activation in glucagon signalling 13/901 17/10654 1.801785093976123e-11 4.29248801800194e-10 3.503161111507757e-10 112/114/108/5573/113/196883/115/5567/111/107/109/5568/5566 13 Lassa_virus R-HSA-111996 Ca-dependent events 19/901 38/10654 2.5884513999232548e-11 6.048016251743759e-10 4.935872912404264e-10 112/114/108/5573/113/808/196883/115/801/816/5567/111/107/109/5594/5568/805/5580/5566 19 Lassa_virus R-HSA-9609507 Protein localization 42/901 163/10654 2.914096236108728e-11 6.680428163909631e-10 5.451993355341454e-10 1891/80273/56993/9804/91452/26520/54543/26521/6342/25813/351/90639/100272147/10469/5824/4580/8604/9218/7416/10063/7316/400916/26517/10440/51/6901/7917/388753/10965/2671/54927/10165/6449/92609/1678/131474/10651/8540/3329/56942/4358/6844 42 Lassa_virus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 29/901 86/10654 3.1094916772423634e-11 6.996356273795318e-10 5.70982682253861e-10 5295/10097/10092/4644/4650/2209/60/5290/5296/917/5335/71/10095/2214/2212/10093/10109/998/4627/10552/4620/10094/4771/4641/5594/5879/10096/3326/5580 29 Lassa_virus R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 24/901 61/10654 3.799700061146879e-11 8.393882862351743e-10 6.850368339904997e-10 10097/10092/4644/4650/2209/60/917/71/10095/2214/2212/10093/10109/998/4627/10552/4620/10094/4771/4641/5594/5879/10096/3326 24 Lassa_virus R-HSA-112315 Transmission across Chemical Synapses 57/901 272/10654 7.679718620715102e-11 1.6662246650301518e-9 1.3598298760739902e-9 2788/10681/51764/112/80331/5864/94235/114/2793/53632/5330/10383/7846/108/23236/54331/160/5573/3084/113/808/6197/3845/196883/2785/5331/115/3265/2783/2890/2784/59345/55970/801/2891/2782/816/5567/2744/2770/111/107/2791/2786/109/2792/4646/2771/2773/5594/5879/5568/2790/805/2787/6844/5566 57 Lassa_virus R-HSA-111933 Calmodulin induced events 18/901 36/10654 8.714082376528837e-11 1.7945101843190742e-9 1.4645255305424024e-9 112/114/108/5573/113/808/196883/115/801/816/5567/111/107/109/5568/805/5580/5566 18 Lassa_virus R-HSA-111997 CaM pathway 18/901 36/10654 8.714082376528837e-11 1.7945101843190742e-9 1.4645255305424024e-9 112/114/108/5573/113/808/196883/115/801/816/5567/111/107/109/5568/805/5580/5566 18 Lassa_virus R-HSA-2514859 Inactivation, recovery and regulation of the phototransduction cascade 18/901 36/10654 8.714082376528837e-11 1.7945101843190742e-9 1.4645255305424024e-9 10681/5145/5148/5158/2779/808/1259/388531/801/2782/2986/8787/6010/1258/2792/3000/805/5957 18 Lassa_virus R-HSA-2514856 The phototransduction cascade 18/901 37/10654 1.563884418600285e-10 3.1668659476655774e-9 2.5845247760025764e-9 10681/5145/5148/5158/2779/808/1259/388531/801/2782/2986/8787/6010/1258/2792/3000/805/5957 18 Lassa_virus R-HSA-1489509 DAG and IP3 signaling 19/901 42/10654 2.358698884386699e-10 4.6980641713603915e-9 3.8341576343266095e-9 112/114/108/5573/113/808/5335/196883/115/801/816/5567/111/107/109/5568/805/5580/5566 19 Lassa_virus R-HSA-611105 Respiratory electron transport 30/901 100/10654 3.784822741353379e-10 7.417031662490896e-9 6.053146048140718e-9 51300/9377/7384/4728/4722/4725/51204/6834/4729/7386/4698/4723/1340/6389/4702/1327/4697/4720/27089/4718/7388/2108/4719/6341/55863/51079/4704/7385/2109/4726 30 Lassa_virus R-HSA-70221 Glycogen breakdown (glycogenolysis) 12/901 17/10654 5.184847453505066e-10 9.999348660331198e-9 8.160612032083161e-9 2548/5837/5256/5257/5836/808/801/5834/5260/5255/5261/805 12 Lassa_virus R-HSA-5620916 VxPx cargo-targeting to cilium 13/901 21/10654 1.1164454746050845e-9 2.1195019556955902e-8 1.7297559820361672e-8 55763/378/54536/8766/60412/10640/4218/11336/6010/1258/149371/55770/23265 13 Lassa_virus R-HSA-170660 Adenylate cyclase activating pathway 9/901 10/10654 1.9720410891177964e-9 3.630348368603216e-8 2.9627794353253022e-8 112/114/108/113/196883/115/111/107/109 9 Lassa_virus R-HSA-399997 Acetylcholine regulates insulin secretion 9/901 10/10654 1.9720410891177964e-9 3.630348368603216e-8 2.9627794353253022e-8 4082/5330/23236/2769/5331/9630/2776/1131/2767 9 Lassa_virus R-HSA-416482 G alpha (12/13) signalling events 25/901 80/10654 4.3436528894513065e-9 7.876922777139309e-8 6.428469790829742e-8 2788/10681/146/6915/51764/8997/94235/2793/54331/147/2785/2783/2784/59345/2768/55970/148/2782/7204/2791/2786/2792/2790/2787/10672 25 Lassa_virus R-HSA-2206281 Mucopolysaccharidoses 9/901 11/10654 1.0028855103108699e-8 1.765950572503923e-7 1.4412176212247743e-7 411/6448/3423/2588/3373/2720/3425/2990/2799 9 Lassa_virus R-HSA-2485179 Activation of the phototransduction cascade 9/901 11/10654 1.0028855103108699e-8 1.765950572503923e-7 1.4412176212247743e-7 5145/5148/5158/2779/1259/2782/6010/1258/2792 9 Lassa_virus R-HSA-1428517 The citric acid (TCA) cycle and respiratory electron transport 39/901 174/10654 1.1297698224969118e-8 1.9609576204767826e-7 1.6003656733715655e-7 51300/9377/1737/4967/7384/4728/4722/4725/51204/6834/4729/7386/4698/4723/81889/7416/1340/6389/4702/1327/4697/4720/27089/4718/5160/8801/7388/2108/1743/3029/4719/6341/55863/51079/4704/7385/2109/4726/8802 39 Lassa_virus R-HSA-8982491 Glycogen metabolism 14/901 29/10654 2.0124694676427394e-8 3.396681573786699e-7 2.772080608626442e-7 2548/5837/5256/5257/5507/5836/808/7316/801/5834/5260/5255/5261/805 14 Lassa_virus R-HSA-1296041 Activation of G protein gated Potassium channels 13/901 25/10654 2.0687607939112404e-8 3.396681573786699e-7 2.772080608626442e-7 2788/94235/2793/54331/2785/2783/2784/55970/2782/2786/2792/2790/2787 13 Lassa_virus R-HSA-1296059 G protein gated Potassium channels 13/901 25/10654 2.0687607939112404e-8 3.396681573786699e-7 2.772080608626442e-7 2788/94235/2793/54331/2785/2783/2784/55970/2782/2786/2792/2790/2787 13 Lassa_virus R-HSA-997272 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits 13/901 25/10654 2.0687607939112404e-8 3.396681573786699e-7 2.772080608626442e-7 2788/94235/2793/54331/2785/2783/2784/55970/2782/2786/2792/2790/2787 13 Lassa_virus R-HSA-8939211 ESR-mediated signaling 45/901 223/10654 2.662090244876457e-8 4.31258619669986e-7 3.519563523752453e-7 5295/2788/3315/10681/7514/1025/8503/51764/94235/2793/1386/1956/857/5290/54331/5296/4343/808/3845/2100/8243/4846/2785/9126/3265/2783/1509/2784/59345/55970/801/2782/2770/2791/2786/2792/2771/2773/5594/208/4609/2790/805/2787/3326 45 Lassa_virus R-HSA-8873719 RAB geranylgeranylation 21/901 65/10654 3.9142391208006956e-8 6.257632278648481e-7 5.106943562041904e-7 5861/5864/9230/10890/5874/326624/5872/8766/5873/9545/4218/51762/401258/5862/7879/51552/53916/5878/57111/5865/10981 21 Lassa_virus R-HSA-373080 Class B/2 (Secretin family receptors) 26/901 95/10654 4.641546234386582e-8 7.323998278934672e-7 5.977220167863514e-7 2788/10681/51764/94235/2793/2535/7855/2642/54331/7481/2785/2783/2641/2784/59345/55970/2782/2791/8323/2786/8322/2792/7976/7474/2790/2787 26 Lassa_virus R-HSA-2980736 Peptide hormone metabolism 25/901 90/10654 6.09960437246261e-8 9.501306810951372e-7 7.754152926936274e-7 1066/4644/2864/51764/55763/2922/25924/1081/338557/54536/1499/1511/2641/1509/2784/60412/5873/10640/3630/11336/149371/183/55770/23265/6844 25 Lassa_virus R-HSA-264876 Insulin processing 13/901 27/10654 6.796030964408727e-8 1.0452123571843802e-6 8.530128139204559e-7 4644/55763/25924/54536/60412/5873/10640/3630/11336/149371/55770/23265/6844 13 Lassa_virus R-HSA-8949215 Mitochondrial calcium ion transport 12/901 23/10654 7.011085088138884e-8 1.064808547761093e-6 8.690055464508985e-7 10730/6687/11331/30968/3954/10367/7416/8165/7417/10939/5245/221154 12 Lassa_virus R-HSA-163200 Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 30/901 123/10654 7.64804572131411e-8 1.1472068581971163e-6 9.362519908353335e-7 51300/9377/7384/4728/4722/4725/51204/6834/4729/7386/4698/4723/1340/6389/4702/1327/4697/4720/27089/4718/7388/2108/4719/6341/55863/51079/4704/7385/2109/4726 30 Lassa_virus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 17/901 47/10654 1.1976359722509713e-7 1.7119149485705062e-6 1.3971183725825576e-6 409/5908/8826/60/808/71/3845/673/3265/1445/801/816/5894/5245/7529/5594/805 17 Lassa_virus R-HSA-6802949 Signaling by RAS mutants 17/901 47/10654 1.1976359722509713e-7 1.7119149485705062e-6 1.3971183725825576e-6 409/5908/8826/60/808/71/3845/673/3265/1445/801/816/5894/5245/7529/5594/805 17 Lassa_virus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 17/901 47/10654 1.1976359722509713e-7 1.7119149485705062e-6 1.3971183725825576e-6 409/5908/8826/60/808/71/3845/673/3265/1445/801/816/5894/5245/7529/5594/805 17 Lassa_virus R-HSA-9649948 Signaling downstream of RAS mutants 17/901 47/10654 1.1976359722509713e-7 1.7119149485705062e-6 1.3971183725825576e-6 409/5908/8826/60/808/71/3845/673/3265/1445/801/816/5894/5245/7529/5594/805 17 Lassa_virus R-HSA-5627123 RHO GTPases activate PAKs 12/901 24/10654 1.2946117538166047e-7 1.8290154428920634e-6 1.4926857675584353e-6 2017/808/801/4659/998/4627/2316/4629/4771/5500/5879/805 12 Lassa_virus R-HSA-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase 9/901 14/10654 2.88689921847897e-7 4.031704080979251e-6 3.290331595652982e-6 114/5573/808/801/5567/107/5568/805/5566 9 Lassa_virus R-HSA-400451 Free fatty acids regulate insulin secretion 8/901 11/10654 3.326051626636455e-7 4.5922190072310145e-6 3.747775875946819e-6 2864/5330/23236/2769/5331/9630/2776/2767 8 Lassa_virus R-HSA-4420097 VEGFA-VEGFR2 Pathway 25/901 99/10654 4.561276206908552e-7 6.226910776847068e-6 5.081871303261805e-6 5295/3315/3685/1003/1432/60/857/5290/5296/808/5335/71/3845/4846/1499/3265/801/5567/998/208/5879/5568/805/5580/5566 25 Lassa_virus R-HSA-1296065 Inwardly rectifying K+ channels 13/901 31/10654 5.071062056008888e-7 6.845933775611999e-6 5.587064861708038e-6 2788/94235/2793/54331/2785/2783/2784/55970/2782/2786/2792/2790/2787 13 Lassa_virus R-HSA-194138 Signaling by VEGF 26/901 107/10654 6.065957878063375e-7 8.09905365038132e-6 6.609753986276112e-6 5295/3315/3685/1003/1432/60/857/5290/5296/808/8829/5335/71/3845/4846/1499/3265/801/5567/998/208/5879/5568/805/5580/5566 26 Lassa_virus R-HSA-417957 P2Y receptors 8/901 12/10654 9.236263030780494e-7 1.2197890850432936e-5 9.954873884433897e-6 5028/5031/5032/10161/2846/5029/2840/27334 8 Lassa_virus R-HSA-6802957 Oncogenic MAPK signaling 20/901 71/10654 9.965523552135897e-7 1.3019474318113027e-5 1.0625379950324864e-5 409/5908/8826/60/808/71/3845/673/3265/10142/1445/55750/801/816/5894/5245/7529/5594/57670/805 20 Lassa_virus R-HSA-6802952 Signaling by BRAF and RAF fusions 19/901 67/10654 1.6584136740914627e-6 2.1435878872565182e-5 1.749412856656392e-5 409/5908/8826/60/808/71/3845/673/3265/10142/1445/55750/801/816/5894/7529/5594/57670/805 19 Lassa_virus R-HSA-5663084 Diseases of carbohydrate metabolism 13/901 34/10654 1.7945437939704038e-6 2.2951270628147795e-5 1.8730861539281114e-5 2548/411/6448/3423/5507/2588/7316/3373/2720/3425/2990/2799/6476 13 Lassa_virus R-HSA-9006931 Signaling by Nuclear Receptors 50/901 299/10654 2.032510372976164e-6 2.5723959407979576e-5 2.099369266824064e-5 5295/2788/3315/10681/7514/1025/8503/1737/51764/94235/2793/1386/2171/1956/857/54659/5290/54331/5296/348/4343/808/3845/2100/8243/4846/2785/9126/3265/2783/1509/2784/59345/55970/5160/801/2782/2770/2791/2786/2792/2771/2773/5594/208/4609/2790/805/2787/3326 50 Lassa_virus R-HSA-438064 Post NMDA receptor activation events 21/901 81/10654 2.3768641478057483e-6 2.977206123282458e-5 2.429740669813364e-5 114/53632/10383/7846/5573/3084/808/6197/3845/3265/2890/801/2891/816/5567/107/5594/5879/5568/805/5566 21 Lassa_virus R-HSA-5620920 Cargo trafficking to the periciliary membrane 16/901 51/10654 2.533878449555259e-6 3.141492159397591e-5 2.563816863030133e-5 10694/2847/55763/378/54536/10576/8766/60412/10640/4218/11336/6010/1258/149371/55770/23265 16 Lassa_virus R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 13/901 36/10654 3.808299496811776e-6 4.6738221097235435e-5 3.814373339709402e-5 10097/10092/60/71/10095/10093/10109/998/10552/10094/5594/5879/10096 13 Lassa_virus R-HSA-3928662 EPHB-mediated forward signaling 14/901 42/10654 4.821805902520303e-6 5.858494171562169e-5 4.7812012212359225e-5 10097/10092/8997/60/71/10095/3265/10093/10109/998/10552/10094/5879/10096 14 Lassa_virus R-HSA-5626467 RHO GTPases activate IQGAPs 12/901 32/10654 5.715424300949179e-6 6.875485668963615e-5 5.6111825862367146e-5 8826/10383/7846/999/60/808/71/1499/801/998/5879/805 12 Lassa_virus R-HSA-391903 Eicosanoid ligand-binding receptors 8/901 15/10654 9.52756625713368e-6 1.134901274746806e-4 9.262092274736767e-5 6915/10800/5731/5737/56413/57105/1241/2840 8 Lassa_virus R-HSA-156580 Phase II - Conjugation of compounds 24/901 109/10654 1.0268615595356163e-5 1.2112978590638581e-4 9.885575769877882e-5 54600/54658/79017/4257/10327/54659/7366/7367/10249/54579/7365/54575/10720/54490/7364/54577/2678/9446/574537/79799/54657/54578/7363/54576 24 Lassa_virus R-HSA-112316 Neuronal System 61/901 413/10654 1.0460191393240843e-5 1.2220319752680409e-4 9.973178433636514e-5 2788/10681/51764/112/80331/5864/94235/114/2793/53632/5330/10383/7846/22941/108/23236/54331/160/5573/3084/113/808/6197/3845/196883/2785/5331/115/3265/2783/2890/2784/59345/55970/801/2891/2782/816/5567/2744/2770/111/107/2791/2786/109/2915/2792/4646/2771/2773/5594/2911/9229/5879/5568/2790/805/2787/6844/5566 61 Lassa_virus R-HSA-418038 Nucleotide-like (purinergic) receptors 8/901 16/10654 1.7643947832360928e-5 2.022395907199861e-4 1.6505063414184703e-4 5028/5031/5032/10161/2846/5029/2840/27334 8 Lassa_virus R-HSA-8949664 Processing of SMDT1 8/901 16/10654 1.7643947832360928e-5 2.022395907199861e-4 1.6505063414184703e-4 10730/6687/11331/30968/10367/10939/5245/221154 8 Lassa_virus R-HSA-8853659 RET signaling 13/901 41/10654 1.9483354065904806e-5 2.2123621672966672e-4 1.8055405341940313e-4 5295/8503/9260/2674/5290/5296/5335/55715/5567/2668/5979/5568/5566 13 Lassa_virus R-HSA-2682334 EPH-Ephrin signaling 21/901 92/10654 2.0353325098548437e-5 2.2897490735866992e-4 1.8686970996912894e-4 10097/10092/8997/23385/60/160/71/10095/3265/10093/10109/6386/998/4627/5663/10552/4629/10094/1212/5879/10096 21 Lassa_virus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 12/901 36/10654 2.3061854807266557e-5 2.5706562927365934e-4 2.097949515059884e-4 409/5908/8826/60/71/3845/673/3265/1445/5894/7529/5594 12 Lassa_virus R-HSA-442755 Activation of NMDA receptors and postsynaptic events 21/901 93/10654 2.4234243524719394e-5 2.676782352957642e-4 2.1845605167737487e-4 114/53632/10383/7846/5573/3084/808/6197/3845/3265/2890/801/2891/816/5567/107/5594/5879/5568/805/5566 21 Lassa_virus R-HSA-8856828 Clathrin-mediated endocytosis 28/901 146/10654 3.0462744899004415e-5 3.334435590296429e-4 2.721280767649328e-4 10097/409/1080/10092/2017/1956/60/160/917/9146/71/7316/8673/10093/10987/10109/6869/551/185/10552/10094/8322/5878/1212/29979/7474/10096/6844 28 Lassa_virus R-HSA-74217 Purine salvage 7/901 13/10654 3.292183512454382e-5 3.571431221100066e-4 2.914696305199274e-4 1633/2766/51292/271/272/132/353 7 Lassa_virus R-HSA-6799198 Complex I biogenesis 15/901 55/10654 3.413564269337147e-5 3.670336802871357e-4 2.995414570764409e-4 51300/4728/4722/4725/4729/4698/4723/4702/4720/4718/4719/55863/51079/4704/4726 15 Lassa_virus R-HSA-2187338 Visual phototransduction 22/901 103/10654 3.915496292507934e-5 4.1730947328045084e-4 3.40572253697366e-4 10681/7804/5145/5148/7276/5158/6121/2779/348/808/1259/388531/801/2782/2986/8787/6010/1258/2792/3000/805/5957 22 Lassa_virus R-HSA-195721 Signaling by WNT 49/901 331/10654 7.299622452508165e-5 7.712209808519496e-4 6.294045171865165e-4 2788/10681/409/7514/51764/5145/94235/2793/5330/2780/5148/2535/5158/7855/857/23236/54331/160/7481/4343/2775/808/3845/2785/5331/7316/1499/2783/2784/59345/55970/801/2782/5707/2791/8323/2786/8322/2792/7976/1212/208/4609/5879/7474/2790/805/2787/5592 49 Lassa_virus R-HSA-5674135 MAP2K and MAPK activation 12/901 40/10654 7.498114930182345e-5 7.853629000147887e-4 6.40945940492901e-4 409/5908/8826/60/71/3845/673/3265/1445/5894/7529/5594 12 Lassa_virus R-HSA-163560 Triglyceride catabolism 9/901 24/10654 8.660266408506001e-5 8.993353578063924e-4 7.339604999381605e-4 2171/2169/857/5501/5567/5499/5500/5568/5566 9 Lassa_virus R-HSA-2029485 Role of phospholipids in phagocytosis 9/901 25/10654 1.252364893400302e-4 0.001289511309729972 0.0010523886972195222 5295/2209/5290/5296/917/5335/2214/2212/5580 9 Lassa_virus R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 25/901 134/10654 1.2702372359848254e-4 0.001296922892202994 0.0010584373961058874 1191/3920/351/5005/81/135228/6810/10447/3827/808/5874/51706/5660/51097/801/2316/813/3959/94121/10487/967/6814/805/6647/139322 25 Lassa_virus R-HSA-1852241 Organelle biogenesis and maintenance 44/901 296/10654 1.5311224221184415e-4 0.001547807854703718 0.0012631882167042688 10694/2847/55763/1432/53632/10383/1386/25813/7846/55735/4580/378/808/54536/1781/10576/8766/10142/22832/10989/60412/801/10640/4218/8655/203068/7019/54927/11336/6010/1258/140735/4751/84303/10651/149371/150737/805/1778/55770/23265/139322/9702/5566 44 Lassa_virus R-HSA-9006925 Intracellular signaling by second messengers 45/901 305/10654 1.5414382750547314e-4 0.001547807854703718 0.0012631882167042688 5295/10014/55004/8503/112/114/1386/1956/5290/108/5296/5573/4343/3084/113/808/5335/196883/23512/648/2100/115/7316/2444/801/5707/816/3630/5567/5978/7157/111/107/1026/6045/109/5371/5594/208/9365/5879/5568/805/5580/5566 45 Lassa_virus R-HSA-392517 Rap1 signalling 7/901 16/10654 1.7492784234012057e-4 0.0017421092495348072 0.0014217603751889006 5908/5567/5894/7529/5568/5566/5592 7 Lassa_virus R-HSA-5673000 RAF activation 10/901 32/10654 2.0465742840885626e-4 0.002021616061111873 0.0016498698978274935 808/3845/673/3265/801/816/5894/5245/7529/805 10 Lassa_virus R-HSA-1660662 Glycosphingolipid metabolism 12/901 46/10654 3.2513503148872216e-4 0.0031857988972483664 0.0025999762280337546 2717/410/23344/411/2760/347527/5476/2720/2629/5660/7368/3074 12 Lassa_virus R-HSA-879415 Advanced glycosylation endproduct receptor signaling 6/901 13/10654 3.6724703080581543e-4 0.0035696411394325264 0.0029132353938448687 830/351/6288/1650/5594/829 6 Lassa_virus R-HSA-373753 Nephrin family interactions 8/901 23/10654 3.931928562913559e-4 0.003791502542809503 0.0030942996710648057 5295/8826/6711/5290/5296/81/84063/6709 8 Lassa_virus R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 7/901 18/10654 4.185284068606279e-4 0.004004031608942228 0.003267747693847589 1956/6197/3845/3265/887/5594/2520 7 Lassa_virus R-HSA-5218920 VEGFR2 mediated vascular permeability 9/901 29/10654 4.507787727279853e-4 0.0042788766317539235 0.0034920526637315973 1003/857/808/4846/1499/801/208/5879/805 9 Lassa_virus R-HSA-114608 Platelet degranulation 23/901 129/10654 4.614194804934082e-4 0.0043459276651123336 0.003546773974906492 1191/3920/351/5005/81/135228/10447/3827/808/5874/51706/5660/51097/801/2316/813/3959/94121/10487/967/805/6647/139322 23 Lassa_virus R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 13/901 55/10654 5.278711032117265e-4 0.004933564541555751 0.0040263528682222376 10294/55860/830/10383/7846/1781/3301/8655/140735/832/829/1778/3326 13 Marburg_virus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 252/1454 309/10654 1.511321757113159e-167 1.902754092205467e-164 1.092924260143937e-164 8454/9354/57154/197131/23352/26224/8945/10293/51088/140460/79754/6737/8065/64410/127544/114088/11065/285231/221687/9666/84937/57531/142678/55070/84708/246184/146330/55819/51320/93611/7319/54850/142686/8916/79791/26046/151636/7321/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/8697/7320/26235/10477/9817/10193/148581/9039/223082/92912/154881/140739/25897/6500/6478/150726/390594/10533/81559/144699/140462/26259/57674/51130/53339/154214/7336/200845/79876/26263/64750/51619/6477/9690/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/9604/9978/22888/23304/7317/80196/114907/140456/64718/54926/4008/7335/84861/11059/55236/84085/55958/54620/4734/84078/7337/26272/84676/27252/51444/7704/8651/3093/26118/222235/51433/25831/7322/64219/10489/23327/9867/26249/140458/55905/55336/26270/143279/51465/63893/89122/6502/23291/118424/10616/27246/89910/55521/25898/9903/201456/55294/26190/55008/7328/79654/10422/84727/135892/7428/22954/8453/401036/83737/51529/9040/90933/140461/7324/63891/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/6233/90135/56658/9870/51434/6468/26267/142685/4012/25847/90025/7327/10425/25793/51343/7311/26091/23295/6047/84541/7318/23194/51666/90293/131405/55175/55284/868/54461/9320/136371/80204/26232/29882/57520/26234/127247/27338/7334/92591/5930/11275/55182/84961/4591/23014/29116/26268/92369/115290/90678/51725/140459/997/23608/51676/55585/64320/51132/84261/7325/57542/9820/55658/7314/996/10324/283807/140691/899 252 Marburg_virus R-HSA-983169 Class I MHC mediated antigen processing & presentation 276/1454 371/10654 1.1762522179939947e-164 7.404507712272197e-162 4.253080388220391e-162 8454/9354/57154/1147/8773/197131/23352/26224/8945/10293/51088/140460/79754/6737/8065/64410/127544/114088/11065/285231/221687/9666/84937/57531/142678/55070/84708/246184/146330/55819/51320/93611/7319/54850/142686/8916/79791/26046/151636/3107/7321/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/8697/10484/7320/26235/10477/10802/9817/10193/148581/9039/223082/92912/154881/140739/821/25897/6500/6478/150726/390594/10533/81559/144699/140462/26259/57674/51130/10333/53339/7099/8517/154214/7336/200845/4615/79876/26263/64750/51619/6477/9690/9554/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/9604/9978/22888/23304/7317/80196/114907/140456/64718/54926/4008/7335/84861/7096/11059/567/55236/84085/55958/54620/4734/84078/7337/26272/84676/27252/51444/7704/8651/3093/26118/222235/51433/25831/7322/64219/10489/23327/9867/26249/140458/55905/55336/9341/26270/143279/51465/63893/89122/6502/23291/118424/10616/3309/27246/89910/55521/114609/25898/9903/201456/55294/26190/55008/7328/79654/10422/84727/135892/7428/22954/8453/401036/83737/51529/9040/90933/140461/7324/63891/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/6233/90135/56658/9870/51434/6468/26267/142685/4012/25847/90025/7327/3685/10425/25793/51343/7311/26091/23295/6047/84541/7318/23194/51666/90293/131405/55175/55284/868/54461/9320/136371/80204/26232/29882/57520/26234/6396/127247/27338/7334/92591/5930/11275/55182/7097/84961/4591/3551/8673/23014/29116/26268/92369/115290/90678/51725/140459/3105/997/23608/51676/55585/64320/51132/84261/7325/10427/57542/9820/55658/7314/996/4360/10324/283807/140691/899 276 Marburg_virus R-HSA-8951664 Neddylation 164/1454 234/10654 2.132976742300872e-89 8.951392395189327e-87 5.141596568283155e-87 8454/9318/51397/26224/54165/8945/56995/23412/51088/9655/140460/79754/8065/64410/149951/29099/285231/23038/146330/93611/54850/142686/55884/79791/7321/51665/9616/122769/9021/4738/26235/9817/9039/154881/140739/6500/150726/3091/390594/144699/140462/28952/55827/26259/51130/53339/28991/200845/332/26263/140825/8452/8450/7323/9306/10517/89890/142689/7316/50717/9978/114907/140456/4008/84861/64708/84085/55958/54620/84078/55527/26272/27252/7704/1643/26118/222235/10980/7322/122416/10489/26249/140458/55336/26270/6502/7347/23291/170622/90864/55832/1642/10920/9903/201456/55294/26190/84727/10987/7428/8453/123879/401036/9040/140461/79176/80176/8139/23142/126433/10116/26043/6233/90135/6468/2873/26267/142685/25793/7311/1154/84541/23194/51666/2034/90293/55175/8533/54461/136371/80204/26232/8835/26234/127247/8883/92591/11275/51122/84961/54939/23014/26268/92369/115290/54951/51725/140459/55208/84259/51676/84261/150684/50813/57542/9820/7314/10537/51138/10324/8451/56929/283807/899 164 Marburg_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 68/1454 78/10654 1.216243454574436e-48 3.828126273273037e-46 2.1988401402437827e-46 1147/3443/3665/3441/351/7186/4790/80143/7321/8737/9140/29110/57506/79132/4214/9636/54476/3449/841/7706/8517/3444/84166/7323/9474/7316/5970/4792/4793/3093/3146/23586/7322/7128/1387/3451/843/3448/2033/64135/3440/54941/83737/3661/9246/7189/6285/51191/6233/10010/7311/55593/84282/7318/79671/5094/7187/8772/5300/3452/9641/1540/3551/3456/4791/3446/7314/3445 68 Marburg_virus R-HSA-913531 Interferon Signaling 113/1454 199/10654 2.4472841825402993e-47 6.162261571636474e-45 3.539545754537232e-45 3839/3443/23165/3665/3460/5777/3837/3838/81929/3441/5903/6737/10379/402569/5335/55706/7175/960/5770/9631/3107/2633/9021/85363/54739/9830/4600/348995/9636/79023/2537/57122/23636/11274/8638/3449/25820/7706/3444/10762/23511/4684/7316/53371/567/4734/3434/6672/6772/8651/23279/4927/9688/3433/3659/79902/23586/8672/6041/3840/3459/9883/4939/7341/3451/3717/23225/3448/1981/3440/5771/10612/3458/3454/3661/8086/7324/3836/9246/5371/51191/4599/6233/684/3716/7311/81603/9972/7318/5610/5300/8021/3452/4940/91543/6396/3437/129401/7334/3456/6773/4938/7297/5781/3430/55746/3105/3446/8480/7314/3445/5595/8554 113 Marburg_virus R-HSA-2990846 SUMOylation 107/1454 188/10654 5.610773867789348e-45 1.1773273832577984e-42 6.762459030125056e-43 1912/10054/23165/23468/5905/81929/5893/286053/5903/7068/29843/55706/7175/1487/55143/9631/5468/1029/7486/9112/8535/6045/9212/51588/3619/4869/80012/7153/348995/51602/79023/6613/57122/23636/8517/332/3183/10762/23511/4929/28996/53371/5970/4792/3190/6996/9759/1911/641/23137/6672/5111/23279/4927/9688/79902/9656/9883/7341/1387/84733/10401/1616/23225/2908/10055/59343/2033/165918/57332/142/7428/3066/3065/23314/7157/1107/1069/8086/7329/5987/5371/7376/8924/672/7158/9972/6612/9063/8021/9641/6117/7690/6294/6396/129401/7703/55746/6304/4791/8480/7508/6015/4193/8554/79677/205564 107 Marburg_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 102/1454 182/10654 4.605880653107055e-42 8.28400534608826e-40 4.7582556521572124e-40 1912/23165/23468/5905/81929/5893/286053/5903/7068/55706/7175/1487/55143/9631/5468/1029/7486/9112/8535/6045/9212/51588/3619/4869/80012/7153/348995/51602/79023/6613/57122/23636/8517/332/3183/10762/23511/4929/28996/53371/5970/4792/3190/6996/9759/1911/641/23137/6672/5111/23279/4927/9688/79902/9656/9883/7341/1387/84733/10401/1616/23225/2908/2033/165918/57332/142/7428/3066/3065/23314/7157/1107/1069/8086/7329/5987/5371/7376/8924/672/7158/9972/6612/9063/8021/9641/6117/7690/6294/6396/129401/7703/55746/6304/4791/8480/7508/6015/4193/8554/79677 102 Marburg_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 64/1454 80/10654 3.8298884066141103e-41 6.027286879908957e-39 3.4620175465051236e-39 3839/23165/3837/3838/81929/5903/402569/5335/55706/7175/9631/4600/348995/9636/79023/57122/23636/11274/8638/25820/7706/10762/23511/7316/53371/4734/3434/6772/23279/4927/9688/79902/23586/8672/6041/3840/9883/4939/23225/1981/3661/8086/7324/3836/9246/51191/4599/6233/3716/7311/9972/7318/5610/5300/8021/4940/6396/129401/7334/4938/55746/8480/7314/5595 64 Marburg_virus R-HSA-73894 DNA Repair 142/1454 334/10654 8.329612617857357e-40 1.1652202539869347e-37 6.692916805225737e-38 9318/6118/2176/80010/25/3838/2237/6917/5893/2178/4436/83990/5888/5892/9156/1763/328/27339/7486/5430/56852/7320/51588/675/2956/404672/9557/4292/9636/11200/545/472/6613/7507/7706/80198/7336/51567/3981/580/11073/2072/8450/353497/54778/7316/9978/116028/197342/6996/64708/641/79008/5111/1643/10459/2966/7415/7517/10980/9656/6119/84464/51455/3364/7341/5437/10401/5889/9937/2177/1642/2965/10920/25898/2033/165918/29089/84126/142/7398/2068/1111/10987/2071/7157/55215/23514/1069/7329/9246/79728/64858/8924/57599/6233/2067/2873/548593/2968/146956/672/7158/7311/6047/9025/2189/7318/55120/2967/2187/6612/8533/7156/8607/5890/5887/6117/2175/2073/5599/7334/5981/10038/7874/2547/5884/5810/348654/2188/5886/4437/55183/50813/5980/57697/7508/7314/22909/51138/8451/8554 142 Marburg_virus R-HSA-1169408 ISG15 antiviral mechanism 59/1454 72/10654 3.868024698050693e-39 4.869843094845823e-37 2.797192597432448e-37 3839/23165/3837/3838/81929/5903/402569/5335/55706/7175/9631/4600/348995/9636/79023/57122/23636/11274/25820/7706/10762/23511/7316/53371/4734/3434/6772/23279/4927/9688/79902/23586/8672/3840/9883/23225/1981/3661/8086/7324/3836/9246/51191/4599/6233/3716/7311/9972/7318/5610/5300/8021/6396/129401/7334/55746/8480/7314/5595 59 Marburg_virus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 60/1454 77/10654 2.0242051495839543e-37 2.3167948030238167e-35 1.3307453949896427e-35 1912/23165/81929/5893/286053/5903/55706/7175/9631/1029/7486/8535/6045/51588/80012/348995/79023/6613/57122/23636/10762/23511/53371/6996/1911/641/23137/6672/23279/4927/9688/79902/9656/9883/7341/84733/23225/165918/57332/142/1069/8086/7329/5371/8924/672/9972/6612/9063/8021/6117/6396/129401/7703/55746/8480/7508/6015/8554/79677 60 Marburg_virus R-HSA-5696395 Formation of Incision Complex in GG-NER 39/1454 43/10654 8.383778429996528e-30 8.795980869471358e-28 5.052329632813697e-28 6118/404672/9557/6613/7507/7336/2072/8450/54778/7316/9978/1643/2966/6119/7341/10401/1642/2965/142/2068/2071/1069/7329/6233/2067/2968/7311/2967/6612/5887/6117/2073/7334/10038/5886/7508/7314/8451/8554 39 Marburg_virus R-HSA-4570464 SUMOylation of RNA binding proteins 41/1454 47/10654 9.805431964406739e-30 9.496183725529295e-28 5.454519643358242e-28 1912/23165/81929/5903/55706/7175/9631/8535/6045/80012/348995/51602/79023/6613/57122/23636/3183/10762/23511/53371/3190/1911/23279/4927/9688/79902/9883/7341/84733/23225/57332/8086/7329/9972/8021/6396/129401/7703/55746/8480/6015 41 Marburg_virus R-HSA-4615885 SUMOylation of DNA replication proteins 39/1454 45/10654 4.1884622052280446e-028 3.76662422598722e-26 2.16351393608396e-26 23165/5905/81929/5903/55706/7175/55143/9631/9212/51588/3619/7153/348995/79023/6613/57122/23636/332/10762/23511/53371/5111/23279/4927/9688/79902/9883/7341/10401/23225/8086/7329/9972/6612/8021/6396/129401/55746/8480 39 Marburg_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 33/1454 34/10654 6.171987448323423e-28 5.180354798292793e-26 2.9755476329811863e-26 7321/9140/29110/57506/9636/54476/7706/84166/7323/9474/7316/3093/23586/7322/7128/64135/54941/83737/3661/9246/51191/6233/7311/55593/84282/7318/79671/5094/7187/5300/9641/1540/7314 33 Marburg_virus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 35/1454 38/10654 2.0738237347945655e-27 1.6318400513164738e-25 9.373137538183333e-26 23165/81929/5903/55706/7175/9631/51588/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/7341/23225/7428/8086/7329/5987/5371/9972/9063/8021/6396/129401/55746/8480/4193/8554 35 Marburg_virus R-HSA-177243 Interactions of Rev with host cellular proteins 33/1454 36/10654 9.813718099445648e-26 7.267924168942394e-24 4.174628070785857e-24 23165/5905/3837/81929/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5902/5901/8086/7514/9972/8021/6396/129401/1104/55746/8480 33 Marburg_virus R-HSA-4551638 SUMOylation of chromatin organization proteins 48/1454 71/10654 1.6643044923587317e-25 1.1640885310442462e-23 6.686416293862273e-24 1912/23165/23468/81929/5903/55706/7175/9631/8535/6045/80012/348995/79023/6613/57122/23636/10762/23511/53371/9759/1911/23279/4927/9688/79902/9883/7341/84733/23225/57332/3066/3065/23314/1107/8086/7329/9972/6612/9063/8021/6396/129401/7703/55746/6304/8480/6015/8554 48 Marburg_virus R-HSA-2980766 Nuclear Envelope Breakdown 40/1454 52/10654 6.135579659836242e-25 4.065628837754646e-23 2.3352594051565084e-23 4000/23165/81929/5903/55706/7175/5579/9631/5578/140609/10783/348995/79023/9133/57122/23636/10762/23511/891/53371/983/23279/4927/9688/79902/9883/23225/7444/8086/2010/4001/23592/9972/5347/8021/6396/129401/55746/7112/8480 40 Marburg_virus R-HSA-165054 Rev-mediated nuclear export of HIV RNA 31/1454 34/10654 4.5878677289547775e-24 2.6607989908590116e-22 1.5283382021823008e-22 23165/5905/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5902/5901/8086/7514/9972/8021/6396/129401/1104/55746/8480 31 Marburg_virus R-HSA-168276 NS1 Mediated Effects on Host Pathways 34/1454 40/10654 4.649529610714715e-24 2.6607989908590116e-22 1.5283382021823008e-22 3839/23165/3837/3838/81929/5903/402569/55706/7175/9631/348995/9636/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/3840/9883/23225/8086/3836/9972/5610/8021/6396/129401/55746/8480 34 Marburg_virus R-HSA-6783310 Fanconi Anemia Pathway 34/1454 40/10654 4.649529610714715e-24 2.6607989908590116e-22 1.5283382021823008e-22 6118/2176/2178/545/80198/2072/353497/7316/197342/79008/6119/84464/9937/2177/29089/84126/7398/55215/64858/57599/6233/2067/548593/146956/7311/2189/55120/2187/6117/2175/2188/57697/7314/22909 34 Marburg_virus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 51/1454 84/10654 8.955671353395798e-24 4.902256623445787e-22 2.815810626902935e-22 9318/6118/404672/9557/6613/7507/7336/2072/8450/54778/7316/9978/64708/5111/1643/2966/10980/6119/7341/10401/1642/2965/10920/142/2068/10987/2071/1069/7329/6233/2067/2873/2968/7311/2967/6612/8533/8607/5887/6117/2073/7334/5981/10038/5886/50813/7508/7314/51138/8451/8554 51 Marburg_virus R-HSA-180746 Nuclear import of Rev protein 30/1454 33/10654 3.121459203256609e-23 1.6374654737083628e-21 9.405449441391624e-22 23165/3837/81929/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/9972/8021/6396/129401/1104/55746/8480 30 Marburg_virus R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 31/1454 35/10654 3.4935313206441877e-23 1.759342373076413e-21 1.010549902013708e-21 23165/81929/5903/55706/7175/9631/140609/10783/348995/79023/9133/57122/23636/10762/23511/891/53371/983/23279/4927/9688/79902/9883/23225/8086/9972/8021/6396/129401/55746/8480 31 Marburg_virus R-HSA-168253 Host Interactions with Influenza Factors 34/1454 42/10654 1.082508000076077e-22 5.2418368157530026e-21 3.010862332195404e-21 3839/23165/3837/3838/81929/5903/402569/55706/7175/9631/348995/9636/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/3840/9883/23225/8086/3836/9972/5610/8021/6396/129401/55746/8480 34 Marburg_virus R-HSA-4085377 SUMOylation of SUMOylation proteins 30/1454 34/10654 2.3091502430965084e-22 1.076748205947594e-20 6.1847415867731045e-21 23165/81929/5903/55706/7175/9631/51588/348995/79023/6613/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/7341/23225/8086/7329/9972/8021/6396/129401/55746/8480 30 Marburg_virus R-HSA-909733 Interferon alpha/beta signaling 44/1454 69/10654 6.33842338310626e-22 2.8500267997609935e-20 1.6370288963135337e-20 3443/3665/5777/3441/10379/5770/3107/9021/54739/4600/9636/2537/11274/8638/3449/3444/3434/6772/8651/3433/3659/6041/4939/3451/3448/3440/3454/3661/4599/684/3716/3452/4940/91543/3437/3456/6773/4938/7297/5781/3430/3105/3446/3445 44 Marburg_virus R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 28/1454 31/10654 1.4295273480230946e-21 5.99924977053692e-20 3.445913291550407e-20 23165/3837/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/3836/9972/8021/6396/129401/55746/8480 28 Marburg_virus R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 28/1454 31/10654 1.4295273480230946e-21 5.99924977053692e-20 3.445913291550407e-20 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/7514/9972/8021/6396/129401/55746/8480 28 Marburg_virus R-HSA-5696398 Nucleotide Excision Repair 57/1454 111/10654 1.982493164947213e-21 8.05148030538239e-20 4.6246954306238884e-20 9318/6118/6917/27339/5430/404672/9557/6613/7507/7336/2072/8450/54778/7316/9978/64708/5111/1643/2966/10980/6119/7341/5437/10401/1642/2965/10920/2033/142/2068/10987/2071/1069/7329/6233/2067/2873/2968/7311/2967/6612/8533/8607/5887/6117/2073/7334/5981/10038/7874/5886/50813/7508/7314/51138/8451/8554 57 Marburg_virus R-HSA-449147 Signaling by Interleukins 139/1454 461/10654 3.5798606648778764e-21 1.4084514303378896e-19 8.09001406832599e-20 5295/729230/8454/3605/7124/1147/834/7291/5777/8945/9655/351/3592/3566/1437/3667/4790/6627/6885/6597/9049/3561/3587/5783/7184/3593/6775/3684/9021/29110/3553/1439/8878/3595/821/6500/5908/3091/8517/6657/6778/4615/7534/332/3597/6776/3688/2357/1436/7316/3565/9978/3560/79155/6774/1435/7335/5970/4792/1441/1026/3718/1440/4793/3627/6772/8651/4609/3146/7867/149233/64127/8503/867/3558/4067/3717/23291/836/3320/2534/5771/3458/998/7157/5478/942/4001/3563/7189/6285/5609/6233/2885/7525/1398/7006/6844/3716/84639/7409/8660/2353/6196/7311/3594/1154/6347/3932/3575/4507/2185/6845/5896/5296/3687/51561/3570/8835/5599/5600/7431/6777/7334/5008/3312/1399/3559/3551/6773/7297/5781/3569/3586/4791/7314/3572/5595/3556 139 Marburg_virus R-HSA-159227 Transport of the SLBP independent Mature mRNA 29/1454 34/10654 8.994302527114235e-21 3.431462691405097e-19 1.9710002667073299e-19 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10482/8086/9972/8021/6396/129401/55746/22916/8480 29 Marburg_virus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 27/1454 30/10654 9.618509751861884e-21 3.561677581645327e-19 2.0457944890183013e-19 90268/11065/7319/7321/65264/7320/10477/92912/7326/7316/7317/54926/55236/3093/7322/7347/29089/7328/7324/6233/7327/7311/55284/27338/7874/997/7314 27 Marburg_virus R-HSA-5685942 HDR through Homologous Recombination (HRR) 42/1454 67/10654 1.4441388742546895e-20 5.194773836247583e-19 2.983829794324727e-19 6118/80010/83990/5888/5892/9156/1763/7486/675/545/472/80198/580/11073/7316/116028/197342/641/79008/5111/7517/6119/84464/3364/5889/84126/1111/23514/79728/6233/548593/146956/672/7311/7156/5890/6117/5981/5884/5810/348654/7314 42 Marburg_virus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 29/1454 35/10654 4.5667263835342866e-20 1.597085699130463e-18 9.17351177043291e-19 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10482/8086/9972/8021/6396/129401/55746/22916/8480 29 Marburg_virus R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 28/1454 33/10654 5.719166855632679e-20 1.9460624516869035e-18 1.117800179180555e-18 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/7514/9972/8021/6396/129401/55746/8480 28 Marburg_virus R-HSA-933541 TRAF6 mediated IRF7 activation 26/1454 29/10654 6.445028436849077e-20 2.1353396847349966e-18 1.226519262081805e-18 3443/3665/3441/7186/80143/29110/57506/3449/7706/3444/23586/1387/3451/3448/2033/64135/3440/3661/7189/10010/84282/3452/9641/3456/3446/3445 26 Marburg_virus R-HSA-2262752 Cellular responses to stress 139/1454 479/10654 1.6749384748174341e-19 5.407044973833717e-18 3.105756362212084e-18 1912/23165/6118/81929/55846/5903/11065/4790/55706/7175/54468/9631/246184/112399/7531/1029/7027/11133/23334/7321/2146/79726/8535/6045/8697/3308/1027/27327/80012/898/3091/348995/1410/10013/545/79023/472/10381/57122/23636/9681/10762/8881/23511/7323/7316/9978/53371/527/6774/5970/1026/1911/6667/525/23279/4927/9688/10121/7415/7867/51433/79902/7322/6119/9883/5928/1387/84733/84219/7846/259217/23225/3310/2908/3309/347733/3320/2033/57332/10376/6009/3301/25994/7428/7157/8453/51529/8086/23135/7324/10963/4001/64682/29945/10393/5609/8131/6233/2056/51434/2475/55004/2353/51343/6196/7311/9972/538/2034/10383/23411/8021/4343/6117/29882/5599/6396/129401/5600/3312/4217/3456/405/3569/3297/57521/55746/10641/7280/8480/7314/996/6015/28956/5595/4193/9296/23043 139 Marburg_virus R-HSA-3371556 Cellular response to heat stress 48/1454 89/10654 2.03732908475321e-19 6.4124932942607284e-018 3.683276529540671e-18 23165/6118/81929/5903/55706/7175/9631/7531/3308/348995/1410/10013/545/79023/472/57122/23636/10762/23511/53371/23279/4927/9688/7415/79902/6119/9883/1387/259217/23225/3310/3309/3320/2033/8086/2475/9972/23411/8021/6117/6396/129401/3312/3297/57521/55746/8480/5595 48 Marburg_virus R-HSA-5693532 DNA Double-Strand Break Repair 69/1454 166/10654 4.0355085389773314e-19 1.2391964025786488e-17 7.117828924974138e-18 6118/80010/25/3838/2237/5893/83990/5888/5892/9156/1763/7486/51588/675/11200/545/472/6613/80198/7336/51567/3981/580/11073/2072/7316/116028/197342/641/79008/5111/7517/9656/6119/84464/3364/7341/5889/165918/84126/142/1111/7157/23514/7329/79728/8924/6233/2067/548593/146956/672/7158/7311/6047/9025/7156/5890/6117/5599/7334/5981/10038/2547/5884/5810/348654/55183/7314 69 Marburg_virus R-HSA-168898 Toll-like Receptor Cascades 66/1454 155/10654 5.235342282950712e-19 1.5693561748178442e-17 9.014235960870022e-18 54106/8454/1147/3665/8945/351/81793/4790/6885/7184/7321/8737/3684/29110/4214/6500/8411/6280/10333/841/7099/8517/4615/7098/7100/7323/7316/79155/7335/5970/4792/7096/4793/8651/26052/3146/7867/7322/64127/23291/114609/3661/7189/6285/5609/6233/51311/10010/2353/6196/7311/7187/8772/9641/5599/5600/7334/7097/3551/5781/4791/1508/51284/7314/5595/148022 66 Marburg_virus R-HSA-5693538 Homology Directed Repair 61/1454 138/10654 1.2264840014743979e-18 3.591031064782016e-17 2.0626548568247524e-17 6118/80010/25/2237/5893/83990/5888/5892/9156/1763/7486/51588/675/545/472/6613/80198/7336/580/11073/2072/7316/116028/197342/641/79008/5111/7517/9656/6119/84464/3364/7341/5889/165918/84126/142/1111/23514/7329/79728/8924/6233/2067/548593/146956/672/7158/7311/6047/9025/7156/5890/6117/7334/5981/10038/5884/5810/348654/7314 61 Marburg_virus R-HSA-180910 Vpr-mediated nuclear import of PICs 27/1454 33/10654 1.7312536036994622e-18 4.953746106949143e-17 2.845385707515623e-17 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/3836/9972/8021/6396/129401/55746/8480 27 Marburg_virus R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 26/1454 31/10654 2.271862747050347e-18 6.217989562035624e-17 3.571555394104321e-17 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/6396/129401/55746/8480 26 Marburg_virus R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 26/1454 31/10654 2.271862747050347e-18 6.217989562035624e-17 3.571555394104321e-17 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/6396/129401/55746/8480 26 Marburg_virus R-HSA-8953897 Cellular responses to external stimuli 139/1454 493/10654 2.7442761337901746e-18 7.351156707323042e-17 4.222436066996304e-17 1912/23165/6118/81929/55846/5903/11065/4790/55706/7175/54468/9631/246184/112399/7531/1029/7027/11133/23334/7321/2146/79726/8535/6045/8697/3308/1027/27327/80012/898/3091/348995/1410/10013/545/79023/472/10381/57122/23636/9681/10762/8881/23511/7323/7316/9978/53371/527/6774/5970/1026/1911/6667/525/23279/4927/9688/10121/7415/7867/51433/79902/7322/6119/9883/5928/1387/84733/84219/7846/259217/23225/3310/2908/3309/347733/3320/2033/57332/10376/6009/3301/25994/7428/7157/8453/51529/8086/23135/7324/10963/4001/64682/29945/10393/5609/8131/6233/2056/51434/2475/55004/2353/51343/6196/7311/9972/538/2034/10383/23411/8021/4343/6117/29882/5599/6396/129401/5600/3312/4217/3456/405/3569/3297/57521/55746/10641/7280/8480/7314/996/6015/28956/5595/4193/9296/23043 139 Marburg_virus R-HSA-176033 Interactions of Vpr with host cellular proteins 28/1454 36/10654 4.810035211384752e-18 1.261632152319459e-16 7.24669778557308e-17 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/292/23279/4927/9688/79902/9883/23225/8086/3836/9972/8021/6396/129401/55746/8480 28 Marburg_virus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 40/1454 69/10654 6.614209153069008e-18 1.6994468007579349e-16 9.761464421392928e-17 23165/6118/81929/5903/55706/7175/9631/7531/3308/348995/545/79023/472/57122/23636/10762/23511/53371/23279/4927/9688/79902/6119/9883/259217/23225/3310/3309/8086/9972/23411/8021/6117/6396/129401/3312/3297/55746/8480/5595 40 Marburg_virus R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 58/1454 132/10654 1.2377323969854487e-17 3.11661017560936e-16 1.7901519089031643e-16 6118/80010/25/5893/83990/5888/5892/9156/1763/7486/51588/675/545/472/6613/80198/7336/580/11073/2072/7316/116028/197342/641/79008/5111/7517/9656/6119/84464/3364/7341/5889/165918/84126/1111/23514/7329/79728/8924/6233/2067/548593/146956/672/7158/7311/6047/9025/7156/5890/6117/7334/5981/5884/5810/348654/7314 58 Marburg_virus R-HSA-5693568 Resolution of D-loop Structures through Holliday Junction Intermediates 26/1454 33/10654 4.3304461552484955e-17 1.0690258253838933e-15 6.140384950785792e-16 80010/83990/5888/5892/9156/1763/7486/675/472/80198/580/116028/197342/641/79008/7517/84464/5889/23514/79728/548593/146956/672/7156/5890/348654 26 Marburg_virus R-HSA-69620 Cell Cycle Checkpoints 95/1454 293/10654 5.100243569308353e-17 1.2348474334152339e-15 7.092848850434895e-16 6118/5905/80010/81929/5903/5000/83990/11065/55143/9156/246184/9735/1763/7531/1029/7486/7321/991/7532/8317/10971/8697/9212/51588/1027/3619/898/7533/2810/348995/4173/11200/545/79023/9133/472/57122/7336/7534/332/580/8881/11073/7316/891/993/5501/116028/983/1026/641/4171/23279/51433/79902/9656/6119/3364/7341/1062/22919/990/165918/84126/4175/1111/7157/51529/7324/64682/29945/10393/8924/6233/51434/672/7514/7158/7311/9025/5347/7156/6117/29882/6396/7334/5001/5884/5810/55746/4176/7529/7314/996/4193 95 Marburg_virus R-HSA-1433557 Signaling by SCF-KIT 30/1454 43/10654 5.2198476596126613e-17 1.2399600383872342e-15 7.122215178061366e-16 5295/5777/4893/3815/10019/5578/6776/9306/6774/6772/6714/8651/8503/867/4067/3717/2534/1111/2885/7525/7006/7409/3932/4254/5296/3845/6777/3265/5781/5879 30 Marburg_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 56/1454 129/10654 8.854114544228752e-17 2.0643204094785183e-15 1.1857264506598738e-15 8454/1147/3665/8945/351/4790/6885/7321/8737/3684/29110/4214/6500/10333/841/7099/8517/4615/7323/7316/79155/7335/5970/4792/7096/4793/8651/26052/3146/7867/7322/64127/23291/114609/3661/7189/6285/5609/6233/10010/2353/6196/7311/7187/8772/9641/5599/5600/7334/7097/3551/5781/4791/7314/5595/148022 56 Marburg_virus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 29/1454 41/10654 9.665798074532761e-17 2.212589050152136e-15 1.2708905793691877e-15 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10482/8086/9972/8021/6396/129401/55746/22916/8480 29 Marburg_virus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 21/1454 23/10654 1.161867371566981e-16 2.612126822862195e-15 1.5003813614032257e-15 11065/246184/7321/991/8697/8881/7316/891/983/51433/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 21 Marburg_virus R-HSA-5693537 Resolution of D-Loop Structures 26/1454 34/10654 1.6025137118320314e-16 3.539587303853557e-15 2.0331060388339898e-15 80010/83990/5888/5892/9156/1763/7486/675/472/80198/580/116028/197342/641/79008/7517/84464/5889/23514/79728/548593/146956/672/7156/5890/348654 26 Marburg_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 46/1454 94/10654 1.745947002174761e-16 3.7899090961000415e-15 2.176888548991036e-15 8454/1147/3665/8945/351/4790/6885/7321/8737/29110/6500/841/8517/7098/7323/7316/79155/7335/5970/4792/4793/3146/7867/7322/64127/23291/3661/7189/6285/5609/6233/10010/2353/6196/7311/7187/8772/9641/5599/5600/7334/3551/4791/7314/5595/148022 46 Marburg_virus R-HSA-3700989 Transcriptional Regulation by TP53 109/1454 365/10654 1.9046683288593957e-16 4.064368518701659e-15 2.3345354896099997e-15 23774/834/6118/2176/5170/80010/27161/6917/4436/83990/5892/9156/1763/7531/1029/7027/7486/5430/9219/7532/10971/55240/22974/9212/1027/4869/404672/27327/898/7533/2810/4292/11200/545/472/8794/7534/332/580/11073/7316/891/28996/116028/80196/1457/983/1026/641/5111/1643/8148/2966/9656/6119/5928/3364/1387/5437/57459/1616/843/2177/2965/54815/2033/84126/5728/6009/8738/2068/1111/3066/3065/2071/7157/1107/55215/8626/5371/6233/2968/2475/55004/672/2353/7311/2967/6880/5300/7156/4343/6117/5600/904/4697/7874/2744/5884/5810/53615/10397/57521/5875/7529/7314/253260/28956/4193 109 Marburg_virus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 29/1454 42/10654 2.718343242132856e-16 5.703990236408777e-15 3.2763189602548634e-15 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10482/8086/9972/8021/6396/129401/55746/22916/8480 29 Marburg_virus R-HSA-166166 MyD88-independent TLR4 cascade 47/1454 99/10654 3.733871209800325e-16 7.582167505062272e-15 4.355126521447916e-15 8454/1147/3665/8945/351/4790/6885/7321/8737/29110/6500/841/7099/8517/7323/7316/79155/7335/5970/4792/4793/3146/7867/7322/64127/23291/3661/7189/6285/5609/6233/10010/2353/6196/7311/7187/8772/9641/5599/5600/7334/3551/5781/4791/7314/5595/148022 47 Marburg_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 47/1454 99/10654 3.733871209800325e-16 7.582167505062272e-15 4.355126521447916e-15 8454/1147/3665/8945/351/4790/6885/7321/8737/29110/6500/841/7099/8517/7323/7316/79155/7335/5970/4792/4793/3146/7867/7322/64127/23291/3661/7189/6285/5609/6233/10010/2353/6196/7311/7187/8772/9641/5599/5600/7334/3551/5781/4791/7314/5595/148022 47 Marburg_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 31/1454 48/10654 4.654332098347581e-16 9.301276367967626e-15 5.342566669281182e-15 5295/5777/1437/3561/1439/7534/6776/7316/3560/3718/8503/867/3558/4067/3717/2534/3563/6233/2885/7525/1398/7006/3716/7409/7311/5296/6777/1399/3559/5781/7314 31 Marburg_virus R-HSA-912694 Regulation of IFNA signaling 22/1454 26/10654 7.020113976369567e-16 1.3809880462889507e-14 7.9322669436939e-15 3443/5777/3441/5770/9021/11274/3449/3444/6772/8651/3451/3448/3440/3454/3716/3452/3456/6773/7297/5781/3446/3445 22 Marburg_virus R-HSA-5696400 Dual Incision in GG-NER 28/1454 41/10654 1.4004073027827979e-15 2.7124812218516036e-14 1.5580239951607807e-14 6118/404672/9557/7507/2072/8450/7316/9978/5111/1643/2966/6119/1642/2965/142/2068/2071/6233/2067/2968/7311/2967/6117/2073/5981/10038/7314/8451 28 Marburg_virus R-HSA-162587 HIV Life Cycle 60/1454 152/10654 1.5553812149102965e-15 2.9670074993516107e-14 1.704221522557215e-14 23165/5905/2237/6917/81929/5903/7852/55706/7175/9631/5430/404672/348995/79023/57122/23636/3981/10762/23511/4686/7316/53371/4836/23279/4927/9688/8148/2966/8731/79902/23327/9883/5437/23225/2965/2068/2071/5902/5901/8086/5478/3836/6233/2968/7514/7311/9972/2967/6880/8021/7251/6396/129401/904/1104/2547/55746/22916/8480/7314 60 Marburg_virus R-HSA-6798695 Neutrophil degranulation 129/1454 480/10654 3.1340647699968136e-15 5.889235142426848e-14 3.382721911999703e-14 2717/10694/8773/2512/23352/80331/5777/3837/23412/10890/7276/4893/5284/29099/9218/4790/327/960/7305/10159/3107/5315/203068/8876/5175/1650/3684/79888/10120/353189/4680/5908/6727/127829/258010/10533/29108/23385/3958/55754/4257/6280/5788/23317/326624/6993/2357/25852/10576/1509/4718/2896/4126/8895/5611/84061/527/5547/9545/1315/567/102/154664/54918/7415/3146/4353/2548/11010/6793/3920/9342/6836/226/197/8904/3310/55832/968/3320/3482/3614/25798/1088/10043/23200/150372/9961/5478/374395/10075/5878/2683/56729/684/10857/55004/6093/3916/3685/719/47/9522/10383/3687/10396/9145/5236/3608/7097/3312/64114/2040/5660/2547/8673/10493/8987/10970/401258/5663/7879/4758/1654/1508/967/22931/5879/28956 129 Marburg_virus R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 28/1454 42/10654 3.6575532599218616e-15 6.771852285649447e-14 3.889688993136716e-14 6118/80010/83990/5888/5892/9156/1763/7486/675/545/472/580/11073/116028/641/7517/6119/3364/5889/84126/1111/79728/672/7156/5890/6117/5884/5810 28 Marburg_virus R-HSA-168325 Viral Messenger RNA Synthesis 28/1454 43/10654 9.128303329124821e-15 1.665584621937413e-13 9.566963214506105e-14 23165/81929/5903/55706/7175/9631/5430/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/5437/23225/8086/9972/8021/6396/129401/55746/8480 28 Marburg_virus R-HSA-5688426 Deubiquitination 91/1454 297/10654 1.1892367789065111e-14 2.1389272923475677e-13 1.2285799505395082e-13 9960/7186/645836/6885/6314/10474/7321/991/8737/4738/7375/9817/57506/100287364/91833/409/6478/1080/3091/100287513/11274/4287/27005/7706/8517/64750/580/7316/993/79155/4792/9986/983/84132/8678/1643/4609/7415/392188/23586/100287144/27430/100287441/64127/7128/3416/9097/7046/6502/7347/9146/2033/408/64135/5728/8724/100287327/7157/9929/9958/4087/63891/7189/57599/6233/377630/672/100287478/7311/55593/84282/114548/78990/7187/23770/728386/8607/5887/7345/1540/29761/7874/100287404/154/10254/100287178/5886/100287205/7314/4193/100287238 91 Marburg_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 126/1454 473/10654 1.389274099689441e-14 2.463515621843671e-13 1.4150204692166727e-13 5295/54106/3675/26999/5170/5777/1173/3643/5590/4893/8065/857/2670/3667/5335/558/5579/5770/1495/1499/5747/4690/3815/10006/5430/10273/10019/10458/5578/10193/2322/3315/5908/3178/10817/23385/2064/5921/6778/6776/9306/3688/4686/7316/1500/5753/9611/9047/527/6774/11059/57498/4233/102/4734/10413/10152/525/6772/6714/8651/26052/7867/3673/8503/23545/2261/867/5437/4067/3717/4914/9146/3320/2534/9475/8471/5771/1445/1111/3630/998/83737/7072/6285/6233/2885/7525/1398/5867/7410/7006/2475/7409/5900/8660/6093/3685/163/6196/7311/3932/3479/5155/2185/1956/4254/5296/3845/5600/6777/3265/1399/5781/3480/22916/5663/10254/4916/7529/10787/7314/5879/253260/5595/9296 126 Marburg_virus R-HSA-162599 Late Phase of HIV Life Cycle 55/1454 139/10654 2.1123149156448362e-14 3.69361733166229e-13 2.1215794547485416e-13 23165/5905/6917/81929/5903/55706/7175/9631/5430/404672/348995/79023/57122/23636/10762/23511/4686/7316/53371/4836/23279/4927/9688/8148/2966/8731/79902/23327/9883/5437/23225/2965/2068/2071/5902/5901/8086/5478/6233/2968/7514/7311/9972/2967/6880/8021/7251/6396/129401/904/1104/55746/22916/8480/7314 55 Marburg_virus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 39/1454 79/10654 2.4339844776041256e-14 4.19778966753917e-13 2.411171357049797e-13 9318/6118/6917/27339/5430/404672/7507/2072/8450/7316/9978/64708/5111/2966/10980/6119/5437/1642/2965/10920/2033/2068/10987/2071/6233/2067/2873/2968/7311/2967/8533/6117/2073/5981/7874/50813/7314/51138/8451 39 Marburg_virus R-HSA-191859 snRNP Assembly 31/1454 53/10654 2.5337530374011355e-14 4.253326765450706e-13 2.443071349746779e-13 23165/81929/5903/6632/55706/7175/6606/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/51808/23225/8086/9972/8021/6396/129401/55746/22916/8480 31 Marburg_virus R-HSA-194441 Metabolism of non-coding RNA 31/1454 53/10654 2.5337530374011355e-14 4.253326765450706e-13 2.443071349746779e-13 23165/81929/5903/6632/55706/7175/6606/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/51808/23225/8086/9972/8021/6396/129401/55746/22916/8480 31 Marburg_virus R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 26/1454 39/10654 3.589148938898492e-14 5.945708571148949e-13 3.415159724408953e-13 6118/80010/83990/5888/5892/9156/1763/7486/675/545/472/580/11073/116028/641/6119/3364/5889/84126/1111/672/7156/5890/6117/5884/5810 26 Marburg_virus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 31/1454 54/10654 5.178027683537012e-14 8.466411498146882e-13 4.863028050020406e-13 9318/6917/27339/5430/404672/7507/8450/7316/9978/64708/2966/10980/5437/1642/2965/10920/2033/2068/10987/2071/6233/2873/2968/7311/2967/8533/7874/50813/7314/51138/8451 31 Marburg_virus R-HSA-5685938 HDR through Single Strand Annealing (SSA) 25/1454 37/10654 7.0039739128459e-14 1.1305132251632038e-12 6.493562858468466e-13 6118/80010/25/5893/83990/5888/9156/1763/7486/545/472/580/11073/2072/116028/641/6119/3364/84126/2067/672/7156/6117/5884/5810 25 Marburg_virus R-HSA-5696394 DNA Damage Recognition in GG-NER 25/1454 38/10654 1.7831089628393688e-13 2.8416888407781837e-12 1.6322396501940657e-12 9318/8450/7316/9978/64708/1643/10980/1642/10920/142/10987/1069/6233/2873/7311/8533/8607/5887/10038/5886/50813/7508/7314/51138/8451 25 Marburg_virus R-HSA-162909 Host Interactions of HIV factors 51/1454 129/10654 1.9601991563810929e-13 3.084863422354745e-12 1.7719168689918562e-12 23165/5905/8945/1173/3837/81929/5903/8065/55706/7175/9631/4869/6500/348995/79023/57122/23636/10762/23511/7316/9978/53371/292/567/23279/4927/9688/79902/9883/23225/2534/5902/5901/8086/5478/3836/6233/7514/163/7311/9972/3932/8021/6396/129401/904/1104/55746/8480/7314/5879 51 Marburg_virus R-HSA-176412 Phosphorylation of the APC/C 17/1454 19/10654 2.3719789590060687e-13 3.686816678257581e-12 2.1176732226603888e-12 11065/246184/7321/8697/8881/891/983/51433/51529/7324/64682/29945/10393/51434/5347/29882/996 17 Marburg_virus R-HSA-933542 TRAF6 mediated NF-kB activation 19/1454 24/10654 7.118619977535455e-13 1.0798003074357997e-11 6.202272573959236e-12 1147/351/7186/4790/57506/4214/7706/8517/5970/4792/4793/3146/23586/64135/7189/6285/84282/3551/4791 19 Marburg_virus R-HSA-982772 Growth hormone receptor signaling 19/1454 24/10654 7.118619977535455e-13 1.0798003074357997e-11 6.202272573959236e-12 5777/3667/5770/2690/9021/6776/6774/6772/8651/4067/3717/5618/2688/8660/1154/8835/6777/2689/5595 19 Marburg_virus R-HSA-877312 Regulation of IFNG signaling 14/1454 14/10654 7.364949769286623e-13 1.09087903053316e-11 6.265907729411653e-12 3460/5777/5770/9021/6772/8651/3459/7341/3717/5771/3458/3716/5781/8554 14 Marburg_virus R-HSA-918233 TRAF3-dependent IRF activation pathway 14/1454 14/10654 7.364949769286623e-13 1.09087903053316e-11 6.265907729411653e-12 3665/80143/29110/57506/7706/23586/1387/2033/64135/3661/84282/7187/9641/3456 14 Marburg_virus R-HSA-8852135 Protein ubiquitination 37/1454 79/10654 8.929618908122117e-13 1.3072546750378773e-11 7.508749314418474e-12 90268/11065/257218/7319/7321/56852/65264/7320/10477/92912/7336/7326/7323/7316/7317/54926/55236/5111/7415/3093/7322/7347/118424/29089/7328/7324/6233/7327/7311/55284/27338/7334/7874/3105/997/6596/7314 37 Marburg_virus R-HSA-69473 G2/M DNA damage checkpoint 41/1454 95/10654 1.5312262460449647e-12 2.2158779813455296e-11 1.2727797108685913e-11 6118/80010/83990/9156/1763/7531/7486/7532/10971/51588/7533/2810/11200/545/472/7336/7534/580/11073/891/116028/983/641/9656/6119/3364/7341/165918/84126/1111/7157/8924/672/7158/9025/7156/6117/7334/5884/5810/7529 41 Marburg_virus R-HSA-162906 HIV Infection 73/1454 233/10654 1.602745861668447e-12 2.2930193634551987e-11 1.3170890035481138e-11 23165/5905/8945/1173/3837/2237/6917/81929/5903/8065/7852/55706/7175/9631/5430/4869/6500/404672/348995/79023/57122/23636/3981/10762/23511/4686/7316/9978/53371/292/567/4836/23279/4927/9688/8148/2966/8731/79902/23327/9883/5437/23225/2965/2534/2068/2071/5902/5901/8086/5478/3836/6233/2968/7514/163/7311/9972/2967/3932/6880/8021/7251/6396/129401/904/1104/2547/55746/22916/8480/7314/5879 73 Marburg_virus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 19/1454 25/10654 2.586432727250357e-12 3.6587851725934824e-11 2.1015721864234123e-11 11065/246184/7321/991/8697/8881/7316/51433/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 19 Marburg_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 40/1454 93/10654 3.2780589973868085e-12 4.535248656824167e-11 2.605004663047701e-11 54106/8454/1147/3665/8945/351/4790/6885/4214/6500/7099/8517/4615/7316/79155/7335/5970/4792/4793/3146/7867/64127/23291/7189/6285/5609/6233/51311/2353/6196/7311/5599/5600/7334/3551/4791/51284/7314/5595/148022 40 Marburg_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 40/1454 93/10654 3.2780589973868085e-12 4.535248656824167e-11 2.605004663047701e-11 54106/8454/1147/3665/8945/351/4790/6885/4214/6500/7099/8517/4615/7316/79155/7335/5970/4792/4793/3146/7867/64127/23291/7189/6285/5609/6233/51311/2353/6196/7311/5599/5600/7334/3551/4791/51284/7314/5595/148022 40 Marburg_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 41/1454 97/10654 3.5049954834762788e-12 4.796510123583299e-11 2.7550708205357015e-11 54106/8454/1147/3665/8945/351/4790/6885/4214/6500/8411/7099/8517/4615/7316/79155/7335/5970/4792/4793/3146/7867/64127/23291/7189/6285/5609/6233/51311/2353/6196/7311/5599/5600/7334/3551/4791/51284/7314/5595/148022 41 Marburg_virus R-HSA-5633007 Regulation of TP53 Activity 56/1454 160/10654 4.862402908585804e-12 6.582543292375836e-11 3.780951667457213e-11 23774/6118/5170/80010/83990/9156/1763/1029/7486/9219/22974/9212/11200/545/472/580/11073/7316/28996/116028/80196/1457/983/641/8148/6119/5928/3364/57459/1616/54815/2033/84126/1111/3066/3065/7157/1107/8626/5371/6233/2475/672/7311/6880/5300/7156/6117/5600/7874/5884/5810/53615/7314/253260/4193 56 Marburg_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 40/1454 95/10654 7.462773309128824e-12 9.890138522308621e-11 5.680803615924101e-11 8454/1147/8945/351/4790/6885/4214/6500/10333/7099/8517/4615/7316/79155/7335/5970/4792/7096/4793/8651/3146/7867/64127/23291/114609/7189/6285/5609/6233/2353/6196/7311/5599/5600/7334/7097/3551/4791/7314/5595 40 Marburg_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 40/1454 95/10654 7.462773309128824e-12 9.890138522308621e-11 5.680803615924101e-11 8454/1147/8945/351/4790/6885/4214/6500/10333/7099/8517/4615/7316/79155/7335/5970/4792/7096/4793/8651/3146/7867/64127/23291/114609/7189/6285/5609/6233/2353/6196/7311/5599/5600/7334/7097/3551/4791/7314/5595 40 Marburg_virus R-HSA-4420097 VEGFA-VEGFR2 Pathway 41/1454 99/10654 7.78773683751847e-12 1.0213292373370578e-10 5.866420183525427e-11 5295/26999/5170/5590/4893/857/5335/558/5579/1495/1499/5747/4690/10006/10458/5578/3315/5921/1500/9047/10152/6714/7867/3320/2534/9475/998/1398/7410/2475/7409/6093/3685/2185/5296/3845/5600/3265/10787/5879/253260 41 Marburg_virus R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 16/1454 19/10654 8.686849314985483e-12 1.1274993079965695e-10 6.476251198475341e-11 11065/246184/7321/991/8697/8881/51433/51529/7324/64682/29945/10393/51434/51343/29882/996 16 Marburg_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 39/1454 92/10654 1.0589977424921581e-11 1.3604879161200275e-10 7.814516101956096e-11 54106/8454/1147/8945/351/4790/6885/4214/6500/7099/8517/4615/7316/79155/7335/5970/4792/4793/3146/7867/64127/23291/7189/6285/5609/6233/51311/2353/6196/7311/5599/5600/7334/3551/4791/51284/7314/5595/148022 39 Marburg_virus R-HSA-5260271 Diseases of Immune System 18/1454 24/10654 1.4588384876967453e-11 1.8366776560102022e-10 1.0549705695238567e-10 1147/81793/4790/10333/7099/8517/4615/7098/7100/5970/4792/7096/114609/7187/7097/3551/4791/148022 18 Marburg_virus R-HSA-5602358 Diseases associated with the TLR signaling cascade 18/1454 24/10654 1.4588384876967453e-11 1.8366776560102022e-10 1.0549705695238567e-10 1147/81793/4790/10333/7099/8517/4615/7098/7100/5970/4792/7096/114609/7187/7097/3551/4791/148022 18 Marburg_virus R-HSA-5689880 Ub-specific processing proteases 68/1454 220/10654 1.875639552346074e-11 2.338049699409611e-10 1.3429540098611284e-10 9960/7186/645836/6885/6314/10474/991/8737/7375/9817/100287364/91833/409/6478/1080/3091/100287513/11274/27005/8517/64750/7316/993/4792/9986/84132/8678/1643/4609/392188/23586/100287144/27430/100287441/3416/9097/7046/6502/9146/408/64135/5728/8724/100287327/7157/9958/4087/63891/7189/57599/6233/377630/100287478/7311/23770/728386/8607/1540/29761/7874/100287404/154/10254/100287178/100287205/7314/4193/100287238 68 Marburg_virus R-HSA-70171 Glycolysis 33/1454 71/10654 1.989158797944764e-11 2.455246006482802e-10 1.4102704790382382e-10 23165/81929/5903/2597/55706/7175/9631/5315/348995/79023/57122/23636/10762/23511/229/53371/23279/4927/9688/79902/9883/2023/226/23225/8086/5213/9972/8021/6396/129401/2026/55746/8480 33 Marburg_virus R-HSA-5689896 Ovarian tumor domain proteases 23/1454 38/10654 2.1457891080620444e-11 2.6228626087865184e-10 1.5065478970246546e-10 7321/8737/57506/7706/8517/7316/79155/983/7415/23586/64127/7128/64135/5728/7157/7189/6233/7311/55593/84282/78990/7187/7314 23 Marburg_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 40/1454 98/10654 2.423719740787383e-11 2.9061553844298243e-10 1.6692686335046939e-10 8454/1147/8945/351/4790/6885/4214/6500/10333/7099/8517/4615/7316/79155/7335/5970/4792/7096/4793/8651/3146/7867/64127/23291/114609/7189/6285/5609/6233/2353/6196/7311/5599/5600/7334/7097/3551/4791/7314/5595 40 Marburg_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 40/1454 98/10654 2.423719740787383e-11 2.9061553844298243e-10 1.6692686335046939e-10 8454/1147/8945/351/4790/6885/4214/6500/10333/7099/8517/4615/7316/79155/7335/5970/4792/7096/4793/8651/3146/7867/64127/23291/114609/7189/6285/5609/6233/2353/6196/7311/5599/5600/7334/7097/3551/4791/7314/5595 40 Marburg_virus R-HSA-73893 DNA Damage Bypass 26/1454 48/10654 3.487941528729297e-11 4.1427531930850806e-10 2.3795589178123405e-10 6118/56852/7320/9636/7706/8450/7316/9978/5111/10459/7415/6119/51455/1642/25898/7398/9246/57599/6233/7311/7318/6117/5981/5980/7314/8451 26 Marburg_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 16/1454 20/10654 3.791541315187253e-11 4.461262164318459e-10 2.5625075096248327e-10 1147/7321/8737/8517/7098/7323/7316/7335/7322/7189/6233/7311/7334/3551/7314/148022 16 Marburg_virus R-HSA-3899300 SUMOylation of transcription cofactors 25/1454 45/10654 3.970783527045503e-11 4.593876236807741e-10 2.638679799913815e-10 1912/1487/8535/6045/51588/4869/80012/6613/28996/1911/7341/1387/84733/10401/1616/2033/57332/7329/6612/9063/7690/6294/7703/6015/8554 25 Marburg_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 12/1454 12/10654 4.01371235940311e-11 4.593876236807741e-10 2.638679799913815e-10 3665/29110/7098/7316/3661/6233/10010/7311/7187/9641/7314/148022 12 Marburg_virus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12/1454 12/10654 4.01371235940311e-11 4.593876236807741e-10 2.638679799913815e-10 1147/8737/57506/841/7706/8517/23586/843/64135/84282/8772/3551 12 Marburg_virus R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 23/1454 39/10654 4.5575758994310484e-11 5.169358610255576e-10 2.969231524807141e-10 10694/26224/22803/10528/898/10517/7203/10576/908/6774/26272/26270/3801/55294/26190/7157/10574/6468/10564/54461/26234/10693/84261 23 Marburg_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 42/1454 108/10654 4.9673934191127335e-11 5.583882423806189e-10 3.2073301493707216e-10 5295/3605/7124/7291/9655/3592/3566/3561/7184/3593/3684/9021/3553/3091/6657/6778/332/3597/3688/3565/6774/1026/3718/6772/8651/4609/149233/3717/3320/7157/3716/2353/6347/3687/51561/3570/7431/5008/3312/7297/3569/3586 42 Marburg_virus R-HSA-1257604 PIP3 activates AKT signaling 76/1454 264/10654 5.7880155473889314e-11 6.44877130456873e-10 3.7041142813751235e-10 5295/1912/1147/5170/27161/3643/3667/5468/23186/3815/2146/9112/9219/8535/10273/6045/1027/27327/80012/2064/4615/2100/7316/1457/4233/1026/1911/4734/6714/8503/5928/2261/84733/57459/54815/2534/57332/5728/6009/3630/3066/3065/7157/1107/23028/942/5987/7189/5371/6233/2885/2475/55004/7409/8660/57504/7311/3932/5155/1956/4254/5296/4343/7874/5781/53615/57521/23608/7314/5879/6015/253260/28956/5595/4193/3556 76 Marburg_virus R-HSA-1433559 Regulation of KIT signaling 14/1454 16/10654 6.746756855288661e-11 7.334234214983822e-10 4.212715944729639e-10 5777/3815/10019/5578/9306/6714/8651/867/4067/2534/2885/7525/3932/4254 14 Marburg_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 36/1454 85/10654 6.815769683503631e-11 7.334234214983822e-10 4.212715944729639e-10 8454/1147/8945/351/81793/4790/6885/4214/6500/8517/4615/7100/7316/79155/7335/5970/4792/4793/3146/7867/64127/23291/7189/6285/5609/6233/2353/6196/7311/5599/5600/7334/3551/4791/7314/5595 36 Marburg_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 36/1454 85/10654 6.815769683503631e-11 7.334234214983822e-10 4.212715944729639e-10 8454/1147/8945/351/81793/4790/6885/4214/6500/8517/4615/7100/7316/79155/7335/5970/4792/4793/3146/7867/64127/23291/7189/6285/5609/6233/2353/6196/7311/5599/5600/7334/3551/4791/7314/5595 36 Marburg_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 36/1454 85/10654 6.815769683503631e-11 7.334234214983822e-10 4.212715944729639e-10 8454/1147/8945/351/81793/4790/6885/4214/6500/8517/4615/7100/7316/79155/7335/5970/4792/4793/3146/7867/64127/23291/7189/6285/5609/6233/2353/6196/7311/5599/5600/7334/3551/4791/7314/5595 36 Marburg_virus R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 18/1454 26/10654 1.2886498606250813e-10 1.3749238767177773e-9 7.89743491747931e-10 80010/83990/5888/5892/9156/1763/7486/675/472/580/116028/641/7517/5889/79728/672/7156/5890 18 Marburg_virus R-HSA-69481 G2/M Checkpoints 55/1454 168/10654 1.4526001305664639e-10 1.5240259439188423e-9 8.753863329060193e-10 6118/80010/5000/83990/9156/1763/7531/7486/7532/8317/10971/51588/7533/2810/4173/11200/545/9133/472/7336/7534/580/11073/7316/891/993/116028/983/641/4171/9656/6119/3364/7341/990/165918/84126/4175/1111/7157/8924/6233/672/7158/7311/9025/7156/6117/7334/5001/5884/5810/4176/7529/7314 55 Marburg_virus R-HSA-194138 Signaling by VEGF 41/1454 107/10654 1.4526061419401196e-10 1.5240259439188423e-9 8.753863329060193e-10 5295/26999/5170/5590/4893/857/5335/558/5579/1495/1499/5747/4690/10006/10458/5578/3315/5921/1500/9047/10152/6714/7867/3320/2534/9475/998/1398/7410/2475/7409/6093/3685/2185/5296/3845/5600/3265/10787/5879/253260 41 Marburg_virus R-HSA-8943724 Regulation of PTEN gene transcription 29/1454 61/10654 1.6711057207759213e-10 1.7387785970718057e-9 9.987382602636433e-10 1912/5468/23186/2146/9112/9219/8535/6045/80012/1911/5928/84733/57459/54815/57332/6009/3066/3065/7157/1107/23028/2475/55004/57504/53615/57521/6015/28956/5595 29 Marburg_virus R-HSA-186763 Downstream signal transduction 19/1454 29/10654 1.6921079805196807e-10 1.7461999569461297e-9 1.003001020377067e-9 5295/4893/5335/4690/5921/6778/6776/6774/6772/6714/2885/1398/5155/5296/3845/6777/3265/1399/5781 19 Marburg_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 32/1454 73/10654 2.6656741491749267e-10 2.728523377082303e-9 1.5672384599770429e-9 57154/5590/892/7027/7321/10273/4738/64750/7323/54778/7316/9611/5501/1024/6667/4609/22938/23327/867/7046/142/3065/9958/9040/4087/6233/7514/7311/56288/25937/904/7314 32 Marburg_virus R-HSA-1059683 Interleukin-6 signaling 11/1454 11/10654 2.96035624678637e-10 3.0057165441161613e-9 1.7264556379815247e-9 9021/6774/6772/867/3717/3716/3570/7297/5781/3569/3572 11 Marburg_virus R-HSA-6782135 Dual incision in TC-NER 30/1454 66/10654 3.246275116825523e-10 3.2696482976666662e-9 1.878055583376113e-9 6118/6917/27339/5430/404672/7507/2072/8450/7316/9978/5111/2966/6119/5437/1642/2965/2033/2068/2071/6233/2067/2968/7311/2967/6117/2073/5981/7874/7314/8451 30 Marburg_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 20/1454 33/10654 4.31818641103108e-10 4.280784796447347e-9 2.4588429874665162e-9 1147/351/4790/6885/8517/7316/7335/5970/4792/4793/3146/64127/7189/6285/6233/7311/7334/3551/4791/7314 20 Marburg_virus R-HSA-5357905 Regulation of TNFR1 signaling 20/1454 33/10654 4.31818641103108e-10 4.280784796447347e-9 2.4588429874665162e-9 7124/1147/90268/7186/8737/55072/7375/841/27005/8517/7316/7128/10616/8567/6233/7311/1540/3551/7185/7314 20 Marburg_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 29/1454 63/10654 4.4113183047338077e-10 4.338945113796769e-9 2.49224973301984e-9 1147/3665/170506/6737/4790/1499/8737/29110/8517/6778/4615/7098/7316/5970/4792/4793/3428/1387/5437/2033/22954/3661/6233/7311/3551/2547/4791/7314/148022 29 Marburg_virus R-HSA-70326 Glucose metabolism 36/1454 91/10654 6.812429151142694e-10 6.648719613402055e-9 3.818962730995537e-9 23165/81929/5903/2597/55706/7175/9631/5091/5315/1468/8402/348995/79023/57122/23636/10762/23511/229/53371/23279/4927/9688/79902/9883/2023/226/23225/8086/5213/9972/8021/6396/129401/2026/55746/8480 36 Marburg_virus R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 15/1454 20/10654 7.850616898551798e-10 7.54498219486772e-9 4.333767624994041e-9 11065/246184/7321/991/8697/8881/51433/51529/7324/64682/29945/10393/51434/29882/996 15 Marburg_virus R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 15/1454 20/10654 7.850616898551798e-10 7.54498219486772e-9 4.333767624994041e-9 11065/246184/7321/991/8697/8881/51433/51529/7324/64682/29945/10393/51434/29882/996 15 Marburg_virus R-HSA-6784531 tRNA processing in the nucleus 27/1454 57/10654 7.924454563555611e-10 7.558248708724632e-9 4.341387787211088e-9 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/9972/8021/6396/129401/55746/8480 27 Marburg_virus R-HSA-5663205 Infectious disease 96/1454 383/10654 8.449342794479539e-10 7.998287652819352e-9 4.594142065538142e-9 3839/23165/5905/8945/1173/3837/3838/2237/6917/81929/5903/8065/7852/402569/55706/7175/9631/1499/3843/5430/4869/821/6500/404672/348995/9636/79023/57122/23636/3981/10762/23511/4686/7316/1500/9978/53371/5611/292/567/4233/4836/6714/23279/4927/9688/8148/2966/8731/79902/6130/3840/23327/9883/867/5437/23225/9146/3320/2965/2534/2068/2071/5902/5901/8086/5478/3836/5609/6233/2885/6844/2968/7514/163/7311/6223/9972/2967/3932/5610/6880/8021/7251/6396/129401/904/1104/2547/55746/22916/10254/6170/8480/7314/5879 96 Marburg_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 36/1454 92/10654 9.741320074088802e-10 9.084682943168741e-9 5.218157419804294e-9 6118/80010/83990/9156/1763/7486/22974/9212/11200/545/472/580/11073/7316/28996/116028/1457/641/8148/6119/3364/84126/1111/7157/6233/672/7311/6880/5300/7156/6117/5600/5884/5810/7314/4193 36 Marburg_virus R-HSA-877300 Interferon gamma signaling 36/1454 92/10654 9.741320074088802e-10 9.084682943168741e-9 5.218157419804294e-9 3665/3460/5777/6737/10379/960/5770/3107/2633/9021/85363/9830/8638/7706/4684/567/6672/6772/8651/3659/3459/4939/7341/3717/5771/10612/3458/3661/5371/3716/81603/4940/4938/5781/3105/8554 36 Marburg_virus R-HSA-9006925 Intracellular signaling by second messengers 81/1454 305/10654 1.026069002527222e-9 9.498682898395385e-9 5.455955145017038e-9 5295/1912/1147/5170/27161/3643/3838/3667/5335/5468/23186/3815/2146/9112/9219/8535/10273/6045/5578/1027/5582/27327/80012/2064/4615/2100/7316/1457/4233/1026/1911/4734/6714/8503/5928/2261/84733/57459/5576/54815/2534/57332/5728/6009/3630/3066/3065/7157/1107/23028/942/5987/7189/5371/6233/2885/2475/55004/7409/8660/57504/7311/3932/5155/1956/4254/5296/4343/7874/5781/53615/57521/23608/7314/5879/6015/253260/28956/5595/4193/3556 81 Marburg_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 26/1454 55/10654 1.7256656300077785e-9 1.585848925678681e-8 9.10896878843906e-9 1147/834/9447/351/4790/6885/10910/29108/841/8517/7316/7335/5970/64127/7128/83737/7189/6233/7311/114548/5600/7334/1540/3551/4791/7314 26 Marburg_virus R-HSA-5693607 Processing of DNA double-strand break ends 37/1454 98/10654 1.859268250145226e-9 1.696245454299159e-8 9.74307618497155e-9 6118/80010/83990/9156/1763/7486/51588/545/472/6613/7336/580/11073/7316/116028/641/9656/6119/3364/7341/165918/84126/1111/7329/8924/6233/672/7158/7311/6047/9025/7156/6117/7334/5884/5810/7314 37 Marburg_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 13/1454 16/10654 2.0356857984448776e-9 1.8438333958576264e-8 1.0590807599633705e-8 8454/1147/8945/4790/6500/8517/7316/79155/23291/6233/7311/3551/7314 13 Marburg_virus R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 31/1454 75/10654 2.946201939389619e-9 2.64947731549395e-8 1.5218351371132843e-8 23165/81929/5903/55706/7175/9631/84271/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10482/8086/9972/8021/6396/129401/79228/55746/22916/8480 31 Marburg_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 18/1454 30/10654 4.1346845550667234e-9 3.691892095623407e-8 2.120588495207793e-8 7124/1147/7186/6885/8737/55072/7375/27005/8517/7316/7128/10616/6233/7311/1540/3551/7185/7314 18 Marburg_virus R-HSA-75893 TNF signaling 22/1454 43/10654 4.767275509786239e-9 4.226760469592166e-8 2.4278119163996632e-8 7124/1147/90268/7186/6885/8737/55072/7375/841/27005/8517/7316/7128/10616/8567/6233/7311/8772/1540/3551/7185/7314 22 Marburg_virus R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 38/1454 106/10654 6.131906372751729e-9 5.398650435870229e-8 3.1009346176521436e-8 9318/1173/10618/4738/409/1080/29978/7316/64708/22905/10980/7037/867/9341/9146/10920/3482/408/10987/115548/29979/6233/2885/2873/6844/163/7311/3575/6845/1956/8533/8673/154/10254/50813/7314/50618/51138 38 Marburg_virus R-HSA-1980143 Signaling by NOTCH1 30/1454 73/10654 6.2310744061324766e-009 5.447862970361658e-8 3.1292018399217916e-8 8454/142678/892/3280/6500/409/3091/10013/23385/7316/9978/9611/8650/9759/102/1024/4609/22938/1387/2033/408/55294/3066/3065/83737/6233/7311/4851/5663/7314 30 Marburg_virus R-HSA-912631 Regulation of signaling by CBL 15/1454 22/10654 6.589748237518721e-9 5.7217193317490144e-8 3.286502387786106e-8 5295/7316/8503/867/4067/2534/6233/2885/7525/1398/7409/7311/5296/1399/7314 15 Marburg_virus R-HSA-937041 IKK complex recruitment mediated by RIP1 16/1454 25/10654 8.112063756097694e-9 6.99526593762123e-8 4.018015717692224e-8 1147/7321/8737/7099/8517/7323/7316/7335/7322/7189/6233/7311/7334/3551/7314/148022 16 Marburg_virus R-HSA-451927 Interleukin-2 family signaling 22/1454 44/10654 8.312051226787639e-9 7.118960880629684e-8 4.089064942930975e-8 5295/5777/1437/3561/6775/1439/6776/3560/6774/3718/6772/8503/3558/3717/3563/2885/3716/3932/2185/5296/6777/3559 22 Marburg_virus R-HSA-1170546 Prolactin receptor signaling 12/1454 15/10654 1.2235154409060193e-8 1.0338294900004553e-7 5.938220472641719e-8 8454/8945/2690/6500/6776/9978/3717/5618/2688/6777/2689/5781 12 Marburg_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 12/1454 15/10654 1.2235154409060193e-8 1.0338294900004553e-7 5.938220472641719e-8 54106/3665/4615/7316/7335/7189/6233/51311/7311/7334/51284/7314 12 Marburg_virus R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 11/1454 13/10654 1.7710118587605436e-8 1.4864692867863493e-7 8.538141382235041e-8 7531/7532/10971/7533/2810/11200/7534/891/983/1111/7529 11 Marburg_virus R-HSA-2586552 Signaling by Leptin 10/1454 11/10654 2.104313065063298e-8 1.7429803611280868e-7 1.0011517144726356e-7 3667/3953/9021/3952/6776/6774/3717/8660/6777/5781 10 Marburg_virus R-HSA-4755510 SUMOylation of immune response proteins 10/1454 11/10654 2.104313065063298e-8 1.7429803611280868e-7 1.0011517144726356e-7 51588/8517/5970/4792/7341/10401/7329/6612/9641/4791 10 Marburg_virus R-HSA-2559583 Cellular Senescence 56/1454 195/10654 2.187470329931261e-8 1.8000164348911486e-7 1.0339127049623505e-7 1912/11065/4790/246184/1029/7027/7321/2146/8535/6045/8697/1027/27327/80012/898/472/8881/7316/6774/5970/1026/1911/6667/7867/51433/5928/84733/57332/7157/51529/23135/7324/4001/64682/29945/10393/5609/6233/51434/2353/51343/6196/7311/4343/29882/5599/5600/4217/3456/3569/7314/996/6015/5595/4193/23043 56 Marburg_virus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 13/1454 18/10654 2.3821455824204058e-8 1.9474813560177215e-7 1.1186151846362398e-7 3665/29110/7099/7316/3661/6233/10010/7311/7187/9641/5781/7314/148022 13 Marburg_virus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 14/1454 21/10654 3.333615413616114e-8 2.70775600370496e-7 1.555309873788978e-7 1147/4790/8737/29110/8517/4615/7098/5970/4792/4793/3661/3551/4791/148022 14 Marburg_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 25/1454 58/10654 3.6451005466304096e-8 2.868238492629804e-7 1.6474895233783493e-7 8454/142678/892/3280/6500/10013/23385/7316/9978/9611/9759/102/1024/4609/22938/1387/2033/55294/3066/3065/6233/7311/4851/5663/7314 25 Marburg_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 25/1454 58/10654 3.6451005466304096e-8 2.868238492629804e-7 1.6474895233783493e-7 8454/142678/892/3280/6500/10013/23385/7316/9978/9611/9759/102/1024/4609/22938/1387/2033/55294/3066/3065/6233/7311/4851/5663/7314 25 Marburg_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 25/1454 58/10654 3.6451005466304096e-8 2.868238492629804e-7 1.6474895233783493e-7 8454/142678/892/3280/6500/10013/23385/7316/9978/9611/9759/102/1024/4609/22938/1387/2033/55294/3066/3065/6233/7311/4851/5663/7314 25 Marburg_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 25/1454 58/10654 3.6451005466304096e-8 2.868238492629804e-7 1.6474895233783493e-7 8454/142678/892/3280/6500/10013/23385/7316/9978/9611/9759/102/1024/4609/22938/1387/2033/55294/3066/3065/6233/7311/4851/5663/7314 25 Marburg_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 25/1454 58/10654 3.6451005466304096e-8 2.868238492629804e-7 1.6474895233783493e-7 8454/142678/892/3280/6500/10013/23385/7316/9978/9611/9759/102/1024/4609/22938/1387/2033/55294/3066/3065/6233/7311/4851/5663/7314 25 Marburg_virus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 17/1454 30/10654 3.7175869995615466e-8 2.907106852452166e-7 1.6698151478906716e-7 6118/56852/7320/8450/7316/9978/5111/6119/1642/7398/57599/6233/7311/6117/5981/7314/8451 17 Marburg_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 22/1454 47/10654 3.8835328859973396e-8 3.0181283354757105e-7 1.7335848555426717e-7 8454/892/3280/6500/3091/10013/7316/9978/9611/9759/1024/4609/22938/1387/2033/55294/3066/3065/6233/7311/4851/7314 22 Marburg_virus R-HSA-6807070 PTEN Regulation 44/1454 140/10654 3.987487397810514e-8 3.079905910333397e-7 1.7690693201781228e-7 1912/27161/5468/23186/2146/9112/9219/8535/10273/6045/27327/80012/7316/1457/1911/4734/5928/84733/57459/54815/57332/5728/6009/3066/3065/7157/1107/23028/5987/5371/6233/2475/55004/57504/7311/4343/7874/53615/57521/23608/7314/6015/28956/5595 44 Marburg_virus R-HSA-110312 Translesion synthesis by REV1 12/1454 16/10654 4.2833560240905974e-8 3.2882592892256474e-7 1.8887455638961745e-7 6118/7316/5111/10459/6119/51455/6233/7311/6117/5981/5980/7314 12 Marburg_virus R-HSA-68886 M Phase 93/1454 395/10654 4.356154119755876e-8 3.323877598044029e-7 1.9092043893284127e-7 10844/4000/23165/5905/81929/5903/11065/55706/7175/55143/5579/9631/246184/9735/7531/7321/991/203068/7532/8697/5578/9212/3619/140609/5861/10783/23244/348995/79023/9133/10381/57122/23636/332/23047/10762/8881/23141/23511/7316/891/5501/53371/26003/1457/983/23279/4927/9688/10121/51433/79902/9883/1062/7846/23225/7283/7444/347733/3320/22919/10376/51529/1069/8086/7324/2010/4001/64682/29945/10393/23592/6233/51434/7514/7311/9972/10383/5347/8021/29882/6396/129401/84930/27229/55746/7112/7280/55755/8480/7314/996/5595 93 Marburg_virus R-HSA-168254 Influenza Infection 47/1454 155/10654 4.804678328096667e-8 3.6440301295624723e-7 2.0930970268880218e-7 3839/23165/3837/3838/81929/5903/402569/55706/7175/9631/3843/5430/821/348995/9636/79023/57122/23636/10762/23511/53371/5611/23279/4927/9688/79902/6130/3840/9883/5437/23225/3320/5901/8086/3836/6233/7514/7311/6223/9972/5610/8021/6396/129401/55746/6170/8480 47 Marburg_virus R-HSA-73887 Death Receptor Signalling 44/1454 141/10654 5.044101506519292e-8 3.8027088603040646e-7 2.1842406145469605e-7 7124/1147/90268/7186/4790/6885/10018/7531/8737/55072/7375/8878/1894/23385/841/27005/8517/4615/7316/5970/4792/7128/843/836/10616/396/8837/3066/3065/8567/7189/6233/7410/7409/7311/8772/5599/1540/3551/7185/8743/5663/7314/5879 44 Marburg_virus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 21/1454 44/10654 5.1744614937703954e-8 3.877766083724362e-7 2.227352785852294e-7 892/7027/7321/64750/7323/54778/7316/9611/1024/6667/4609/22938/23327/142/3065/4087/6233/7311/25937/904/7314 21 Marburg_virus R-HSA-69242 S Phase 48/1454 161/10654 6.22977171680492e-8 4.640995616246979e-7 2.6657447333821116e-7 8454/6118/2237/5000/11065/246184/1763/7027/7321/8697/1027/6500/898/23244/4173/23047/8881/7316/5422/9978/5753/993/1026/5111/4171/4609/51433/6119/5928/6502/990/4175/51529/7324/64682/29945/10393/6233/51434/51343/7311/6117/29882/5001/5981/4176/7314/996 48 Marburg_virus R-HSA-68875 Mitotic Prophase 44/1454 142/10654 6.360439209549975e-8 4.7104664498961287e-7 2.7056481343410724e-7 4000/23165/81929/5903/55706/7175/5579/9631/5578/140609/5861/10783/348995/79023/9133/57122/23636/10762/23511/891/53371/26003/983/23279/4927/9688/79902/9883/23225/7444/8086/2010/4001/23592/9972/5347/8021/6396/129401/84930/55746/7112/8480/5595 44 Marburg_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 13/1454 19/10654 6.598102764778219e-8 4.829657779567313e-7 2.774110525950206e-7 5295/4893/5335/7316/867/3320/6233/2885/7311/1956/3845/3265/7314 13 Marburg_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 13/1454 19/10654 6.598102764778219e-8 4.829657779567313e-7 2.774110525950206e-7 5295/4893/5335/7316/867/3320/6233/2885/7311/1956/3845/3265/7314 13 Marburg_virus R-HSA-69239 Synthesis of DNA 39/1454 119/10654 6.660952000753709e-8 4.847478941588971e-7 2.784346835727288e-7 8454/6118/2237/5000/11065/246184/1763/7321/8697/6500/898/4173/8881/7316/5422/9978/5111/4171/51433/6119/6502/990/4175/51529/7324/64682/29945/10393/6233/51434/51343/7311/6117/29882/5001/5981/4176/7314/996 39 Marburg_virus R-HSA-72202 Transport of Mature Transcript to Cytoplasm 31/1454 84/10654 7.047096303808344e-8 5.099019681893509e-7 2.92882949831599e-7 23165/81929/5903/55706/7175/9631/84271/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10482/8086/9972/8021/6396/129401/79228/55746/22916/8480 31 Marburg_virus R-HSA-9027284 Erythropoietin activates RAS 11/1454 14/10654 7.239434861465245e-8 5.208256280334138e-7 2.991573984858119e-7 4893/4067/3717/2057/2885/2056/7409/8660/3845/3265/1399 11 Marburg_virus R-HSA-5663202 Diseases of signal transduction 89/1454 377/10654 7.515257239700663e-8 5.375970945899508e-7 3.087907729470308e-7 5295/8454/4000/1147/5170/7276/4893/3667/5335/1487/142678/1499/10018/892/3815/5430/3280/1027/6500/409/5908/10533/10013/23385/2064/6776/2100/4686/7316/9978/9611/8546/6774/4233/9759/102/1026/1024/6772/6714/4609/7415/22938/8503/2261/867/1387/5437/7046/3717/3320/2534/2033/408/55294/5728/1445/3066/3065/4087/942/6233/2885/2475/7409/56829/8660/7311/3932/5155/1956/4254/5296/4140/3845/6777/3265/369/5781/4851/22916/5663/7529/7314/1523/5879/253260/5595/4193 89 Marburg_virus R-HSA-9006335 Signaling by Erythropoietin 15/1454 25/10654 8.424215776894298e-8 5.992139922660973e-7 3.441829461032639e-7 5295/4893/5335/6776/4067/3717/2057/2885/2056/7409/8660/3845/6777/3265/1399 15 Marburg_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 42/1454 134/10654 8.810150330259029e-8 6.231449025728156e-7 3.579286384913041e-7 5295/8454/1147/5170/8945/4893/4773/5335/4790/6885/7321/4214/6500/8517/7316/7335/5970/4792/7322/4067/23291/2534/7189/5609/6233/2885/7410/7006/7409/3702/2353/7311/5296/3845/5599/7334/3265/3551/997/7314/5879/5595 42 Marburg_virus R-HSA-210990 PECAM1 interactions 10/1454 12/10654 1.1070418822075116e-7 7.700363147509708e-7 4.4230169995729017e-7 5777/5335/5175/6714/4067/2534/7525/3685/3932/5781 10 Marburg_virus R-HSA-8984722 Interleukin-35 Signalling 10/1454 12/10654 1.1070418822075116e-7 7.700363147509708e-7 4.4230169995729017e-7 3592/6775/3595/821/6774/6772/3717/3716/7297/3572 10 Marburg_virus R-HSA-9020558 Interleukin-2 signaling 10/1454 12/10654 1.1070418822075116e-7 7.700363147509708e-7 4.4230169995729017e-7 3561/6776/3560/3718/3558/3716/3932/2185/6777/3559 10 Marburg_virus R-HSA-447115 Interleukin-12 family signaling 24/1454 57/10654 1.1755660313427496e-7 8.132074909123746e-7 4.670988221703117e-7 3592/6627/9049/3593/6775/3595/821/5908/6774/6772/149233/3717/3458/998/5478/4001/3716/3594/4507/6845/51561/7297/3586/3572 24 Marburg_virus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 26/1454 65/10654 1.225040006307597e-7 8.428007475088878e-7 4.840969136228468e-7 6118/6917/27339/5430/404672/8450/7316/9978/5111/2966/6119/5437/1642/2965/2033/2068/2071/6233/2968/7311/2967/6117/5981/7874/7314/8451 26 Marburg_virus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 12/1454 17/10654 1.2747591858786023e-7 8.628611908715916e-7 4.956194457830219e-7 1147/4790/8737/8517/4615/7098/5970/4792/4793/3551/4791/148022 12 Marburg_virus R-HSA-5655862 Translesion synthesis by POLK 12/1454 17/10654 1.2747591858786023e-7 8.628611908715916e-7 4.956194457830219e-7 6118/7316/5111/10459/6119/51455/6233/7311/6117/5981/5980/7314 12 Marburg_virus R-HSA-5656121 Translesion synthesis by POLI 12/1454 17/10654 1.2747591858786023e-7 8.628611908715916e-7 4.956194457830219e-7 6118/7316/5111/10459/6119/51455/6233/7311/6117/5981/5980/7314 12 Marburg_virus R-HSA-110056 MAPK3 (ERK1) activation 9/1454 10/10654 1.411139247014371e-7 9.450129319101559e-7 5.42806642048641e-7 983/3717/3716/3570/7297/5781/3569/3572/5595 9 Marburg_virus R-HSA-3215018 Processing and activation of SUMO 9/1454 10/10654 1.411139247014371e-7 9.450129319101559e-7 5.42806642048641e-7 10054/29843/6613/7341/10055/59343/7329/6612/205564 9 Marburg_virus R-HSA-69306 DNA Replication 40/1454 127/10654 1.5367220261495727e-7 1.0236682703292656e-6 5.879855371566453e-7 8454/6118/2237/5000/11065/246184/1763/7321/8317/8697/6500/898/4173/8881/7316/5422/9978/5111/4171/51433/6119/6502/990/4175/51529/7324/64682/29945/10393/6233/51434/51343/7311/6117/29882/5001/5981/4176/7314/996 40 Marburg_virus R-HSA-8856828 Clathrin-mediated endocytosis 44/1454 146/10654 1.5593894980832553e-7 1.0333007253088518e-6 5.935183297413831e-7 9318/1173/5868/10618/4738/409/1080/29978/7316/64708/22905/26052/10980/7037/867/9341/9146/10920/3482/408/10987/115548/5878/29979/6233/2885/2873/10096/6844/163/7311/3575/6845/1956/8533/3312/8673/154/10254/50813/7314/50618/51138/11252 44 Marburg_virus R-HSA-3232118 SUMOylation of transcription factors 13/1454 20/10654 1.6490892023390046e-7 1.087017437562726e-6 6.243727098412214e-7 1029/9112/51588/6613/7341/10401/7157/7329/7158/6612/9063/4193/8554 13 Marburg_virus R-HSA-8848021 Signaling by PTK6 23/1454 54/10654 1.6707394575835714e-7 1.0898761539366407e-6 6.260147299481392e-7 120892/4893/5770/9021/1027/898/3091/2064/5921/7316/5753/6774/867/2908/6233/1398/7311/2034/1956/3845/3265/7314/5879 23 Marburg_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 23/1454 54/10654 1.6707394575835714e-7 1.0898761539366407e-6 6.260147299481392e-7 120892/4893/5770/9021/1027/898/3091/2064/5921/7316/5753/6774/867/2908/6233/1398/7311/2034/1956/3845/3265/7314/5879 23 Marburg_virus R-HSA-168638 NOD1/2 Signaling Pathway 18/1454 36/10654 1.9172676360348288e-7 1.244247398849407e-6 7.146841377948601e-7 1147/834/6885/841/8517/7316/7335/64127/7128/83737/7189/6233/7311/5600/7334/1540/3551/7314 18 Marburg_virus R-HSA-9006936 Signaling by TGF-beta family members 34/1454 102/10654 2.9086859498973983e-7 1.8779669799593972e-6 1.078686773322274e-6 57154/5590/892/7027/9765/7321/10273/4738/64750/7323/54778/7316/9611/5501/1024/6667/4609/22938/23327/867/7046/142/3065/9958/9040/4087/6233/7514/7311/56288/25937/10589/904/7314 34 Marburg_virus R-HSA-176187 Activation of ATR in response to replication stress 18/1454 37/10654 3.259254966787628e-7 2.09357245060491e-6 1.2025285511187433e-6 6118/5000/8317/4173/545/993/4171/6119/3364/990/84126/4175/1111/6117/5001/5884/5810/4176 18 Marburg_virus R-HSA-912526 Interleukin receptor SHC signaling 15/1454 27/10654 3.421472864541899e-7 2.1866164144458125e-6 1.2559721388940874e-6 5295/5777/1437/3561/1439/3560/3718/8503/3558/3717/3563/2885/3716/5296/3559 15 Marburg_virus R-HSA-450294 MAP kinase activation 25/1454 64/10654 3.67103903080895e-7 2.3342616867618527e-6 1.340778210614433e-6 8454/1147/8945/4790/6885/6500/8517/7316/79155/7335/7867/64127/23291/7189/5609/6233/2353/6196/7311/5599/5600/7334/3551/7314/5595 25 Marburg_virus R-HSA-209560 NF-kB is activated and signals survival 10/1454 13/10654 4.206844203312377e-7 2.6615160060152175e-6 1.528750049021742e-6 4790/8878/7316/5970/4792/7189/6233/7311/3551/7314 10 Marburg_virus R-HSA-69052 Switching of origins to a post-replicative state 31/1454 90/10654 4.2503727032471103e-7 2.675609616694056e-6 1.5368452879635602e-6 8454/5000/11065/246184/7321/8697/6500/898/4173/8881/7316/9978/4171/51433/6502/990/4175/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/5001/4176/7314/996 31 Marburg_virus R-HSA-68882 Mitotic Anaphase 54/1454 201/10654 4.3021019632451077e-7 2.694699687425667e-6 1.5478104471062524e-6 4000/5905/81929/5903/11065/55143/246184/9735/7321/991/8697/9212/3619/23244/348995/79023/10381/57122/332/23047/8881/23141/7316/5501/23279/51433/79902/1062/7846/7444/347733/22919/10376/51529/7324/2010/4001/64682/29945/10393/23592/6233/51434/7514/7311/10383/5347/29882/6396/55746/7112/7280/7314/996 54 Marburg_virus R-HSA-390466 Chaperonin-mediated protein folding 32/1454 95/10654 4.947740306559128e-7 3.083764874236605e-6 1.7712858731662952e-6 10694/26224/22803/10528/5203/898/10381/10517/7203/10576/908/6774/1457/26272/26270/7846/347733/3801/10376/55294/26190/7157/10574/6468/10564/10383/54461/26234/10693/7280/84261/5201 32 Marburg_virus R-HSA-2555396 Mitotic Metaphase and Anaphase 54/1454 202/10654 5.109013768994176e-7 3.16859523899688e-6 1.8200116459937767e-6 4000/5905/81929/5903/11065/55143/246184/9735/7321/991/8697/9212/3619/23244/348995/79023/10381/57122/332/23047/8881/23141/7316/5501/23279/51433/79902/1062/7846/7444/347733/22919/10376/51529/7324/2010/4001/64682/29945/10393/23592/6233/51434/7514/7311/10383/5347/29882/6396/55746/7112/7280/7314/996 54 Marburg_virus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 25/1454 65/10654 5.199788421122301e-7 3.2090851089181258e-6 1.8432686508312798e-6 2176/6917/4436/5892/5430/404672/4292/545/472/1643/2966/9656/5437/2177/2965/2068/1111/2071/7157/55215/2968/672/2353/2967/904 25 Marburg_virus R-HSA-193639 p75NTR signals via NF-kB 11/1454 16/10654 6.66828992046101e-7 4.095305858468493e-6 2.3523056099392624e-6 4790/8878/4615/7316/5970/4792/7189/6233/7311/3551/7314 11 Marburg_virus R-HSA-1227986 Signaling by ERBB2 21/1454 50/10654 7.622630088810666e-7 4.658685088258558e-6 2.675905401641762e-6 5295/4893/8065/5335/10273/5578/10193/2064/7316/5753/6714/3320/2534/6233/2885/7525/7311/1956/3845/3265/7314 21 Marburg_virus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 18/1454 39/10654 8.765480954015018e-7 5.3312756140603426e-6 3.062235146406467e-6 6118/9636/7706/7316/5111/10459/7415/6119/51455/25898/9246/6233/7311/7318/6117/5981/5980/7314 18 Marburg_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 16/1454 32/10654 9.259407456806094e-7 5.604612494287919e-6 3.2192373091223617e-6 57154/10273/4738/64750/7316/5501/23327/867/7046/9958/9040/4087/6233/7514/7311/7314 16 Marburg_virus R-HSA-69618 Mitotic Spindle Checkpoint 35/1454 112/10654 1.1157120773593017e-6 6.720964140647659e-6 3.860459315768523e-6 5905/81929/5903/11065/55143/246184/9735/7321/991/8697/9212/3619/348995/79023/57122/332/8881/5501/23279/51433/79902/1062/22919/51529/7324/64682/29945/10393/51434/7514/5347/29882/6396/55746/996 35 Marburg_virus R-HSA-1266695 Interleukin-7 signaling 17/1454 36/10654 1.183321856013577e-6 7.094296270100445e-6 4.074897819956528e-6 5295/3667/6597/3561/6776/6774/3718/8651/8503/3716/8660/1154/3575/5896/5296/8835/6777 17 Marburg_virus R-HSA-448424 Interleukin-17 signaling 26/1454 72/10654 1.287576649332065e-6 7.682744082981372e-6 4.41289677271703e-6 8454/3605/1147/8945/4790/6885/6500/8517/7316/79155/7335/7867/64127/23291/7189/5609/6233/2353/6196/7311/5599/5600/7334/3551/7314/5595 26 Marburg_virus R-HSA-5619102 SLC transporter disorders 32/1454 99/10654 1.398453942125224e-6 8.304969401583288e-6 4.770297210725068e-6 23165/81929/5903/55706/7175/9631/5002/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/682/8086/6520/6575/9972/8021/6396/129401/213/55746/6566/8480 32 Marburg_virus R-HSA-389356 CD28 co-stimulation 16/1454 33/10654 1.5704939389470608e-6 9.282872625043895e-6 5.331995730450362e-6 5295/5170/6714/8503/4067/2534/998/942/2885/7525/2475/7409/3932/5296/5879/253260 16 Marburg_virus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 13/1454 23/10654 1.6301877898511033e-6 9.590684240292238e-6 5.508799860441259e-6 7321/64750/7323/54778/7316/9611/23327/142/3065/4087/6233/7311/7314 13 Marburg_virus R-HSA-4655427 SUMOylation of DNA methylation proteins 11/1454 17/10654 1.6556429600528759e-6 9.683411649353126e-6 5.5620616220940575e-6 1912/8535/6045/80012/1911/7341/84733/57332/7329/7703/6015 11 Marburg_virus R-HSA-109581 Apoptosis 48/1454 178/10654 1.6613319430184872e-6 9.683411649353126e-6 5.5620616220940575e-6 4000/3837/1676/7186/219699/1499/10018/7531/1029/5747/7027/8737/7532/10971/7533/2810/118/1829/841/7099/7534/100506658/7316/6774/5339/4836/3146/836/8837/3002/7157/8626/4001/3836/6233/6093/7311/1677/8772/5599/7431/26060/8743/6304/7529/7314/5595/148022 48 Marburg_virus R-HSA-8876384 Listeria monocytogenes entry into host cells 12/1454 20/10654 1.741615086225902e-6 1.0104577850499589e-5 5.803975572336622e-6 1499/7316/1500/4233/6714/867/9146/6233/2885/7311/10254/7314 12 Marburg_virus R-HSA-168255 Influenza Life Cycle 41/1454 144/10654 2.1195071056801277e-6 1.224063966078569e-5 7.030909616621186e-6 23165/3837/81929/5903/55706/7175/9631/3843/5430/821/348995/79023/57122/23636/10762/23511/53371/5611/23279/4927/9688/79902/6130/9883/5437/23225/3320/5901/8086/3836/6233/7514/7311/6223/9972/8021/6396/129401/55746/6170/8480 41 Marburg_virus R-HSA-391251 Protein folding 32/1454 101/10654 2.2840241686352854e-6 1.3070847401417383e-5 7.507773224174359e-6 10694/26224/22803/10528/5203/898/10381/10517/7203/10576/908/6774/1457/26272/26270/7846/347733/3801/10376/55294/26190/7157/10574/6468/10564/10383/54461/26234/10693/7280/84261/5201 32 Marburg_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 32/1454 101/10654 2.2840241686352854e-6 1.3070847401417383e-5 7.507773224174359e-6 8454/1147/5170/8945/4773/4790/6885/7321/3553/9039/6500/29108/841/8517/7316/64581/7335/5970/4792/6714/7322/23291/9040/7189/6233/7311/5971/7334/3551/997/4791/7314 32 Marburg_virus R-HSA-5689877 Josephin domain DUBs 9/1454 12/10654 2.3936174270579807e-6 1.3636037740570126e-5 7.832413300256407e-6 4287/7316/7415/9929/6233/7311/5887/5886/7314 9 Marburg_virus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 60/1454 244/10654 2.5434318842825885e-6 1.4424237577980985e-5 8.28514795875836e-6 23165/23451/81929/5903/6632/6627/55706/7175/9631/27339/84271/5430/51639/3178/23450/348995/79023/57122/23636/3183/10762/5093/23511/10594/4686/53371/9343/3190/23279/4927/9688/79902/22938/988/9883/5437/23225/10482/10421/8086/2521/3191/10285/27316/10286/9972/5094/8021/3192/6396/129401/79228/3312/5356/55746/22916/56259/26121/8480/1994 60 Marburg_virus R-HSA-446652 Interleukin-1 family signaling 40/1454 140/10654 2.5560945686527598e-6 1.4431045120779483e-5 8.289058148050253e-6 8454/1147/834/5777/8945/351/4790/6885/5783/29110/3553/8878/6500/8517/4615/7316/3565/9978/79155/6774/7335/5970/4792/4793/3146/64127/23291/5771/7189/6285/6233/84639/7311/5599/7334/3551/5781/4791/7314/3556 40 Marburg_virus R-HSA-6806834 Signaling by MET 27/1454 79/10654 2.7757248978308427e-6 1.5537851979292736e-5 8.924797717297862e-6 5295/3675/4893/5770/5747/5908/3688/7316/6774/4233/6714/3673/867/9146/5771/6233/2885/1398/5867/7311/3845/3265/1399/5781/10254/7314/5879 27 Marburg_virus R-HSA-5357801 Programmed Cell Death 48/1454 181/10654 2.7768202504693132e-6 1.5537851979292736e-5 8.924797717297862e-6 4000/3837/1676/7186/219699/1499/10018/7531/1029/5747/7027/8737/7532/10971/7533/2810/118/1829/841/7099/7534/100506658/7316/6774/5339/4836/3146/836/8837/3002/7157/8626/4001/3836/6233/6093/7311/1677/8772/5599/7431/26060/8743/6304/7529/7314/5595/148022 48 Marburg_virus R-HSA-937039 IRAK1 recruits IKK complex 10/1454 15/10654 3.3985645335080583e-6 1.8849307258531476e-5 1.0826866842198171e-5 1147/8517/7316/7335/7189/6233/7311/7334/3551/7314 10 Marburg_virus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 10/1454 15/10654 3.3985645335080583e-6 1.8849307258531476e-5 1.0826866842198171e-5 1147/8517/7316/7335/7189/6233/7311/7334/3551/7314 10 Marburg_virus R-HSA-9020958 Interleukin-21 signaling 8/1454 10/10654 4.118396700251542e-6 2.274149756849426e-5 1.3062504769495888e-5 3561/6775/6776/6774/3718/6772/3716/6777 8 Marburg_virus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 28/1454 86/10654 5.372702402412872e-6 2.9409705759294806e-5 1.6892661558158546e-5 8454/8945/11065/246184/7321/991/8697/9212/6500/8881/7316/891/983/51433/6502/51529/7324/64682/29945/10393/6233/51434/51343/7311/5347/29882/7314/996 28 Marburg_virus R-HSA-453276 Regulation of mitotic cell cycle 28/1454 86/10654 5.372702402412872e-6 2.9409705759294806e-5 1.6892661558158546e-5 8454/8945/11065/246184/7321/991/8697/9212/6500/8881/7316/891/983/51433/6502/51529/7324/64682/29945/10393/6233/51434/51343/7311/5347/29882/7314/996 28 Marburg_virus R-HSA-1643713 Signaling by EGFR in Cancer 13/1454 25/10654 5.675778122455106e-6 3.084397927995807e-5 1.771649493359909e-5 5295/4893/5335/7316/867/3320/6233/2885/7311/1956/3845/3265/7314 13 Marburg_virus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 15/1454 32/10654 5.683719772001805e-6 3.084397927995807e-5 1.771649493359909e-5 892/7027/54778/7316/1024/6667/4609/22938/3065/4087/6233/7311/25937/904/7314 15 Marburg_virus R-HSA-6804757 Regulation of TP53 Degradation 16/1454 36/10654 6.564587059006997e-6 3.547130947334682e-5 2.0374390375142563e-5 5170/1029/11200/472/7316/80196/983/1616/7157/6233/2475/7311/7874/7314/253260/4193 16 Marburg_virus R-HSA-5357786 TNFR1-induced proapoptotic signaling 9/1454 13/10654 6.832716692193122e-6 3.673821738487893e-5 2.1102090500741462e-5 7124/7186/8737/7375/841/27005/7128/8772/1540 9 Marburg_virus R-HSA-9613829 Chaperone Mediated Autophagy 12/1454 22/10654 6.857411505517513e-6 3.673821738487893e-5 2.1102090500741462e-5 2670/1080/10013/7316/3920/3320/6233/7311/200894/7431/3312/7314 12 Marburg_virus R-HSA-5578749 Transcriptional regulation by small RNAs 32/1454 106/10654 7.208521455652367e-6 3.845562929095903e-5 2.2088555932351365e-5 23165/27161/81929/5903/55706/7175/9631/5430/27327/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/5437/23225/5901/8086/9972/8021/6396/129401/55746/8480/10526 32 Marburg_virus R-HSA-110320 Translesion Synthesis by POLH 11/1454 19/10654 7.767845056204482e-6 4.126462837874027e-5 2.3702018892349447e-5 6118/7316/5111/7415/6119/25898/6233/7311/6117/5981/7314 11 Marburg_virus R-HSA-72306 tRNA processing 32/1454 107/10654 8.959611197124679e-6 4.739559032428559e-5 2.722358643266101e-5 23165/81929/5903/115708/55706/7175/9631/3028/348995/79023/57122/23636/10762/23511/54901/53371/54931/23279/4927/9688/55644/79902/9883/23225/5901/8086/9972/8021/6396/129401/55746/8480 32 Marburg_virus R-HSA-5621481 C-type lectin receptors (CLRs) 39/1454 142/10654 9.604087660597953e-6 5.0592244203735656e-5 2.905971470086234e-5 8454/1147/5170/8945/4893/4773/4790/6885/7321/3553/9039/6500/29108/841/8517/7316/64581/7335/5970/4792/6714/7322/1387/4067/23291/2534/2033/9040/7189/6233/7311/5971/3845/7334/3265/3551/997/4791/7314 39 Marburg_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 13/1454 26/10654 9.93654329415371e-6 5.212545003058134e-5 2.994037387317368e-5 57154/10273/64750/7316/5501/23327/7046/9958/4087/6233/7514/7311/7314 13 Marburg_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 16/1454 37/10654 1.0109332428575633e-5 5.2811823765878515e-5 3.0334620565326314e-5 5170/1029/11200/472/7316/80196/983/1616/7157/6233/2475/7311/7874/7314/253260/4193 16 Marburg_virus R-HSA-177929 Signaling by EGFR 19/1454 49/10654 1.0445086701579676e-5 5.434034775739179e-5 3.121259053495101e-5 5295/4893/5335/7316/102/6714/867/9146/1445/998/6233/2885/7311/1956/3845/3265/5781/10254/7314 19 Marburg_virus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 26/1454 80/10654 1.1965573874298334e-5 6.199447534050042e-5 3.5609050256196466e-5 8454/8945/11065/246184/7321/991/8697/6500/8881/7316/891/983/51433/51529/7324/64682/29945/10393/6233/51434/51343/7311/5347/29882/7314/996 26 Marburg_virus R-HSA-2424491 DAP12 signaling 14/1454 30/10654 1.2475815038376472e-5 6.41104127890448e-5 3.6824425054198224e-5 5295/4893/5335/7305/567/2534/22914/2885/7410/3932/5296/3845/3265/5879 14 Marburg_virus R-HSA-4090294 SUMOylation of intracellular receptors 14/1454 30/10654 1.2475815038376472e-5 6.41104127890448e-5 3.6824425054198224e-5 7068/5468/51588/6613/4929/9759/7341/10401/2908/7329/7376/6612/9063/8554 14 Marburg_virus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 12/1454 23/10654 1.2559837377153638e-5 6.42798181212863e-5 3.6921729902030595e-5 6885/8517/7316/7335/64127/7189/5609/6233/7311/5599/7334/7314 12 Marburg_virus R-HSA-1236394 Signaling by ERBB4 21/1454 58/10654 1.2715730637134737e-5 6.481418976580014e-5 3.7228668006441784e-5 5295/4893/2670/23385/6776/7316/9611/11059/4734/10413/6714/83737/6285/6233/2885/7311/1956/3845/3265/5663/7314 21 Marburg_virus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 8/1454 11/10654 1.3283634573108812e-5 6.743587067558062e-5 3.8734537146543945e-5 6885/7098/7316/7189/6233/7311/7314/148022 8 Marburg_virus R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 16/1454 38/10654 1.5263489383754735e-5 7.717563507689643e-5 4.432896726543861e-5 1912/6597/196528/8535/6045/80012/865/28996/1457/1911/6603/84733/2033/57332/861/6015 16 Marburg_virus R-HSA-195258 RHO GTPase Effectors 72/1454 327/10654 1.8373687263201083e-5 9.252988905748065e-5 5.31483079992385e-5 26999/5905/5170/25/81929/5590/5903/55143/5579/1495/1499/9735/7531/5747/4690/991/10006/7532/10971/10458/4771/5578/9212/389/1027/3619/1080/7533/2810/348995/79023/10381/57122/6280/30851/7534/332/3688/5501/5216/10152/6714/23279/79902/1062/7846/347733/22919/79784/9475/3895/10376/998/23028/2885/10096/7514/6093/57120/9928/10383/5347/5300/6396/5600/5586/55746/7280/7529/10787/5879/5595 72 Marburg_virus R-HSA-8878166 Transcriptional regulation by RUNX2 34/1454 121/10654 2.0868088863288195e-5 1.046730035015133e-4 6.012320003807502e-5 8454/57154/8493/7291/25/10273/3280/6500/100526737/10013/3958/3678/7316/9978/891/865/11059/9759/983/1026/10413/6772/6714/6502/2908/55294/23314/861/6233/7525/7311/25937/7314/5595 34 Marburg_virus R-HSA-5683057 MAPK family signaling cascades 66/1454 294/10654 2.137216452087973e-5 1.0677601242772849e-4 6.133114881305086e-5 27161/2674/4893/1437/3667/3561/5747/3815/7010/1439/2322/3315/27327/409/5908/10817/2064/5921/8452/4684/7316/9978/3560/4233/983/5597/84078/3718/6714/4609/2261/3558/3717/2534/408/1445/998/1847/3563/1739/6233/2885/3716/8660/7514/7311/5155/1956/4254/5896/4140/4343/3570/3845/3265/3559/369/7297/5781/3569/7529/7314/3572/5879/28956/5595 66 Marburg_virus R-HSA-6783783 Interleukin-10 signaling 18/1454 47/10654 2.1731283412178724e-5 1.0729288555267848e-4 6.162803593051304e-5 729230/7124/3592/1437/3587/3593/3553/2357/6774/1435/1440/3627/942/3716/6347/7297/3569/3586 18 Marburg_virus R-HSA-73762 RNA Polymerase I Transcription Initiation 18/1454 47/10654 2.1731283412178724e-5 1.0729288555267848e-4 6.162803593051304e-5 9112/9219/404672/2966/5928/5437/57459/2965/54815/2068/3066/3065/2071/1107/2968/57504/2967/53615 18 Marburg_virus R-HSA-9020591 Interleukin-12 signaling 18/1454 47/10654 2.1731283412178724e-5 1.0729288555267848e-4 6.162803593051304e-5 3592/6627/9049/3593/6775/3595/5908/3717/3458/998/5478/4001/3716/3594/4507/6845/7297/3586 18 Marburg_virus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 12/1454 24/10654 2.2006977820923904e-5 1.0780850224335874e-4 6.192420136381208e-5 6885/8517/7316/7335/7867/64127/7189/6233/7311/5600/7334/7314 12 Marburg_virus R-HSA-6783589 Interleukin-6 family signaling 12/1454 24/10654 2.2006977820923904e-5 1.0780850224335874e-4 6.192420136381208e-5 9021/6774/6772/867/3717/3716/3570/5008/7297/5781/3569/3572 12 Marburg_virus R-HSA-2467813 Separation of Sister Chromatids 47/1454 190/10654 2.581985511593215e-5 1.2599688988743633e-4 7.237144212421617e-5 5905/81929/5903/11065/55143/246184/9735/7321/991/8697/9212/3619/23244/348995/79023/10381/57122/332/23047/8881/7316/5501/23279/51433/79902/1062/7846/347733/22919/10376/51529/7324/64682/29945/10393/6233/51434/7514/7311/10383/5347/29882/6396/55746/7280/7314/996 47 Marburg_virus R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 13/1454 28/10654 2.7419019608176712e-5 1.3328396018028756e-4 7.655706755056858e-5 10694/5203/10381/7203/10576/908/7846/347733/10574/10383/10693/7280/5201 13 Marburg_virus R-HSA-6807004 Negative regulation of MET activity 11/1454 21/10654 2.786510099520397e-5 1.349313928960069e-4 7.75033375858507e-5 5770/7316/4233/867/9146/5771/6233/2885/7311/10254/7314 11 Marburg_virus R-HSA-9020702 Interleukin-1 signaling 30/1454 103/10654 2.9780619809368952e-5 1.43654407432933e-4 8.251375603563811e-5 8454/1147/8945/351/4790/6885/3553/8878/6500/8517/4615/7316/9978/79155/7335/5970/4792/4793/3146/64127/23291/7189/6285/6233/7311/7334/3551/4791/7314/3556 30 Marburg_virus R-HSA-2871796 FCERI mediated MAPK activation 14/1454 32/10654 3.0967680882364904e-5 1.4768299329885384e-4 8.482773830217182e-5 4893/5335/4214/4067/5609/2885/7410/7409/2353/3845/5599/3265/5879/5595 14 Marburg_virus R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 14/1454 32/10654 3.0967680882364904e-5 1.4768299329885384e-4 8.482773830217182e-5 10694/5203/10381/7203/10576/908/7846/347733/10376/10574/10383/10693/7280/5201 14 Marburg_virus R-HSA-5656169 Termination of translesion DNA synthesis 14/1454 32/10654 3.0967680882364904e-5 1.4768299329885384e-4 8.482773830217182e-5 6118/9636/7706/7316/5111/6119/51455/9246/6233/7311/7318/6117/5981/7314 14 Marburg_virus R-HSA-5654741 Signaling by FGFR3 16/1454 40/10654 3.296828659156162e-5 1.5663046346707952e-4 8.996708197975305e-5 5295/4893/5335/10817/7316/6714/2261/867/6233/2885/7311/3845/3265/5781/7314/5595 16 Marburg_virus R-HSA-5675482 Regulation of necroptotic cell death 10/1454 18/10654 3.3463227511297936e-5 1.583842234463312e-4 9.097442540665485e-5 7186/8737/841/7316/8837/6233/7311/8772/8743/7314 10 Marburg_virus R-HSA-3371511 HSF1 activation 8/1454 12/10654 3.506366886521049e-5 1.6487986425519605e-4 9.470546109553921e-5 6118/7531/10013/7415/6119/3320/6117/3297 8 Marburg_virus R-HSA-168273 Influenza Viral RNA Transcription and Replication 36/1454 134/10654 3.509754060396548e-5 1.6487986425519605e-4 9.470546109553921e-5 23165/81929/5903/55706/7175/9631/3843/5430/348995/79023/57122/23636/10762/23511/53371/5611/23279/4927/9688/79902/6130/9883/5437/23225/3320/8086/6233/7311/6223/9972/8021/6396/129401/55746/6170/8480 36 Marburg_virus R-HSA-4419969 Depolymerisation of the Nuclear Lamina 9/1454 15/10654 3.6919826846787846e-5 1.7026396337035127e-4 9.7798037569860215e-005 4000/5579/5578/891/983/2010/4001/23592/7112 9 Marburg_virus R-HSA-5358508 Mismatch Repair 9/1454 15/10654 3.6919826846787846e-5 1.7026396337035127e-4 9.7798037569860215e-005 6118/4436/9156/2956/4292/5111/6119/6117/4437 9 Marburg_virus R-HSA-5637810 Constitutive Signaling by EGFRvIII 9/1454 15/10654 3.6919826846787846e-5 1.7026396337035127e-4 9.7798037569860215e-005 5295/4893/5335/867/3320/2885/1956/3845/3265 9 Marburg_virus R-HSA-5637812 Signaling by EGFRvIII in Cancer 9/1454 15/10654 3.6919826846787846e-5 1.7026396337035127e-4 9.7798037569860215e-005 5295/4893/5335/867/3320/2885/1956/3845/3265 9 Marburg_virus R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 9/1454 15/10654 3.6919826846787846e-5 1.7026396337035127e-4 9.7798037569860215e-005 7316/4233/867/9146/6233/2885/7311/10254/7314 9 Marburg_virus R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 12/1454 25/10654 3.7081931388741366e-5 1.7038741466578606e-4 9.786894684619791e-5 10694/10381/7203/10576/908/7846/347733/10376/10574/10383/10693/7280 12 Marburg_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 19/1454 53/10654 3.835999527979723e-5 1.7561903293550804e-4 1.0087393974055766e-4 10018/7531/1029/7027/7532/10971/7533/2810/841/7534/6774/4836/836/3002/7157/8626/5599/7529/5595 19 Marburg_virus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 23/1454 72/10654 5.113860212166588e-5 2.3243140819919616e-4 1.335064398920177e-4 8773/10890/7531/7532/10971/57186/7533/2810/10381/7534/5872/8766/7846/347733/10376/5867/6844/4012/10383/7280/7529/5879/57148 23 Marburg_virus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 23/1454 72/10654 5.113860212166588e-5 2.3243140819919616e-4 1.335064398920177e-4 11065/246184/7321/991/8697/9212/8881/7316/51433/6502/51529/7324/64682/29945/10393/6233/51434/51343/7311/5347/29882/7314/996 23 Marburg_virus R-HSA-166520 Signaling by NTRKs 29/1454 101/10654 5.370001286725754e-5 2.4232371397805465e-4 1.3918848835995444e-4 5295/1173/4893/3667/5335/10817/6774/57498/6714/26052/7867/4914/2534/2885/1398/5900/8660/163/6196/5296/3845/5600/3265/1399/5781/4916/7529/5879/5595 29 Marburg_virus R-HSA-2219528 PI3K/AKT Signaling in Cancer 29/1454 101/10654 5.370001286725754e-5 2.4232371397805465e-4 1.3918848835995444e-4 5295/1147/5170/3667/3815/1027/2064/2100/4233/1026/6714/8503/2261/2534/5728/942/2885/2475/7409/8660/3932/5155/1956/4254/5296/5781/5879/253260/4193 29 Marburg_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 31/1454 112/10654 6.520217848669632e-5 2.9317693826696664e-4 1.6839810759533972e-4 5295/8454/1147/5777/8945/4893/4773/4790/6885/5579/5966/4690/6500/8517/7316/5970/4792/4793/4067/23291/2534/5478/6233/2885/7409/7311/3845/3265/3551/7314/6786 31 Marburg_virus R-HSA-6804758 Regulation of TP53 Activity through Acetylation 13/1454 30/10654 6.725564257867176e-5 3.0133400002330156e-4 1.7308344802977147e-4 23774/9219/5928/57459/54815/2033/3066/3065/7157/1107/5371/5300/53615 13 Marburg_virus R-HSA-9639288 Amino acids regulate mTORC1 19/1454 55/10654 6.898846226278602e-5 3.080016808115163e-4 1.7691330188329224e-4 81929/55846/54468/11133/23334/79726/9681/527/525/84219/6009/8131/2475/55004/6396/57521/10641/28956/9296 19 Marburg_virus R-HSA-187687 Signalling to ERKs 14/1454 34/10654 7.004220081037063e-5 3.1160116897617176e-4 1.7898081441965639e-4 4893/57498/6714/7867/4914/2885/1398/5900/3845/5600/3265/1399/7529/5595 14 Marburg_virus R-HSA-8877330 RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) 7/1454 10/10654 7.153705041047453e-5 3.1713079741826564e-4 1.8215698158634546e-4 4773/865/3558/50943/3458/861/3559 7 Marburg_virus R-HSA-1295596 Spry regulation of FGF signaling 9/1454 16/10654 7.416487366072902e-5 3.259261573285842e-4 1.8720895454599502e-4 7316/6714/867/6233/2885/7311/5781/7314/5595 9 Marburg_virus R-HSA-205043 NRIF signals cell death from the nucleus 9/1454 16/10654 7.416487366072902e-5 3.259261573285842e-4 1.8720895454599502e-4 8878/23385/7316/7189/6233/7311/5599/5663/7314 9 Marburg_virus R-HSA-453279 Mitotic G1-G1/S phases 38/1454 149/10654 7.42977022663254e-5 3.259261573285842e-4 1.8720895454599502e-4 8454/6118/25/5000/1029/7027/8317/1027/6500/7153/898/4173/7316/5422/891/5753/993/983/1026/5111/6714/4171/4609/6119/5928/4067/3717/6502/990/4175/3065/6233/7311/6117/5001/7083/4176/7314 38 Marburg_virus R-HSA-209543 p75NTR recruits signalling complexes 8/1454 13/10654 8.023319234203794e-5 3.5074162902300616e-4 2.0146273077112595e-4 8878/4615/7316/7189/6233/7311/3551/7314 8 Marburg_virus R-HSA-9614085 FOXO-mediated transcription 21/1454 65/10654 8.923013097850941e-5 3.887222660966898e-4 2.2327845559000532e-4 857/10018/7532/10971/1027/2810/4287/7534/114907/1026/84676/1387/2908/2033/3630/3066/3065/4087/56729/23411/7529 21 Marburg_virus R-HSA-2122948 Activated NOTCH1 Transmits Signal to the Nucleus 13/1454 31/10654 1.0145264429351542e-4 4.404444109156411e-4 2.529871746992562e-4 142678/409/23385/7316/8650/102/408/83737/6233/7311/4851/5663/7314 13 Marburg_virus R-HSA-114604 GPVI-mediated activation cascade 14/1454 35/10654 1.0218893426415739e-4 4.421163856995675e-4 2.539475414703423e-4 5295/5170/5777/5590/8503/4067/2534/998/7410/7409/3932/5296/5781/5879 14 Marburg_virus R-HSA-75153 Apoptotic execution phase 18/1454 52/10654 1.033671742785927e-4 4.456824397833843e-4 2.5599584978151834e-4 4000/3837/1676/1499/5747/118/1829/841/100506658/5339/3146/836/4001/3836/6093/1677/7431/6304 18 Marburg_virus R-HSA-5213460 RIPK1-mediated regulated necrosis 10/1454 20/10654 1.0889406768106945e-4 4.6490445634895535e-4 2.6703679738450094e-4 7186/8737/841/7316/8837/6233/7311/8772/8743/7314 10 Marburg_virus R-HSA-5218859 Regulated Necrosis 10/1454 20/10654 1.0889406768106945e-4 4.6490445634895535e-4 2.6703679738450094e-4 7186/8737/841/7316/8837/6233/7311/8772/8743/7314 10 Marburg_virus R-HSA-187037 Signaling by NTRK1 (TRKA) 24/1454 80/10654 1.0893313313974728e-4 4.6490445634895535e-4 2.6703679738450094e-4 5295/1173/4893/3667/5335/6774/57498/6714/26052/7867/4914/2885/1398/5900/8660/163/6196/5296/3845/5600/3265/1399/7529/5595 24 Marburg_virus R-HSA-69231 Cyclin D associated events in G1 16/1454 44/10654 1.2782454329340656e-4 5.418555555771005e-4 3.1123679334598727e-4 8454/25/1029/7027/1027/6500/7316/5753/1026/6714/4067/3717/6502/6233/7311/7314 16 Marburg_virus R-HSA-69236 G1 Phase 16/1454 44/10654 1.2782454329340656e-4 5.418555555771005e-4 3.1123679334598727e-4 8454/25/1029/7027/1027/6500/7316/5753/1026/6714/4067/3717/6502/6233/7311/7314 16 Marburg_virus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 25/1454 86/10654 1.3851656089664016e-4 5.833367841150849e-4 3.350632253560164e-4 5295/26999/25/5335/5747/4690/10006/10458/4771/10152/6714/4067/3320/2534/998/2885/7525/1398/7410/10096/7409/5296/10787/5879/5595 25 Marburg_virus R-HSA-9034015 Signaling by NTRK3 (TRKC) 9/1454 17/10654 1.3853669455949992e-4 5.833367841150849e-4 3.350632253560164e-4 5295/4893/3667/5335/6714/2885/3845/3265/4916 9 Marburg_virus R-HSA-186797 Signaling by PDGF 19/1454 58/10654 1.5532111843692816e-4 6.518309603736418e-4 3.7440564339006894e-4 5295/4893/5335/4690/5921/6778/6776/6774/6772/6714/2885/1398/5155/5296/3845/6777/3265/1399/5781 19 Marburg_virus R-HSA-5684996 MAPK1/MAPK3 signaling 56/1454 255/10654 1.6380440207195104e-4 6.825161428900934e-4 3.9203092693908633e-4 2674/4893/1437/3667/3561/5747/3815/7010/1439/2322/409/5908/10817/2064/5921/8452/4684/7316/9978/3560/4233/983/84078/3718/6714/2261/3558/3717/2534/408/1445/1847/3563/1739/6233/2885/3716/8660/7311/5155/1956/4254/4140/3570/3845/3265/3559/369/7297/5781/3569/7529/7314/3572/28956/5595 56 Marburg_virus R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 8/1454 14/10654 1.6480135618632917e-4 6.825161428900934e-4 3.9203092693908633e-4 6118/4436/9156/2956/4292/5111/6119/6117 8 Marburg_virus R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 8/1454 14/10654 1.6480135618632917e-4 6.825161428900934e-4 3.9203092693908633e-4 6118/4436/9156/4292/5111/6119/6117/4437 8 Marburg_virus R-HSA-8983432 Interleukin-15 signaling 8/1454 14/10654 1.6480135618632917e-4 6.825161428900934e-4 3.9203092693908633e-4 3561/6776/3560/6774/3718/2885/3716/6777 8 Marburg_virus R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 7/1454 11/10654 1.734805281258649e-4 7.114396902620974e-4 4.0864434363953084e-4 3091/1387/2033/25994/2056/2034/405 7 Marburg_virus R-HSA-8934903 Receptor Mediated Mitophagy 7/1454 11/10654 1.734805281258649e-4 7.114396902620974e-4 4.0864434363953084e-4 9140/9474/192111/1457/6714/81631/84557 7 Marburg_virus R-HSA-9020956 Interleukin-27 signaling 7/1454 11/10654 1.734805281258649e-4 7.114396902620974e-4 4.0864434363953084e-4 821/6774/6772/3717/3716/7297/3572 7 Marburg_virus R-HSA-5218921 VEGFR2 mediated cell proliferation 10/1454 21/10654 1.8255676466822049e-4 7.438154262695456e-4 4.2724066539624414e-4 5170/5590/4893/5335/5579/5578/5921/6714/3845/3265 10 Marburg_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 10/1454 21/10654 1.8255676466822049e-4 7.438154262695456e-4 4.2724066539624414e-4 4893/4790/5970/1387/4067/2534/2033/5971/3845/3265 10 Marburg_virus R-HSA-5654743 Signaling by FGFR4 15/1454 41/10654 1.9111631575994677e-4 7.761788436831387e-4 4.458299114671763e-4 5295/4893/5335/10817/7316/6714/867/6233/2885/7311/3845/3265/5781/7314/5595 15 Marburg_virus R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 19/1454 59/10654 2.0018331221669596e-4 8.103883925428302e-4 4.654795582767646e-4 257218/7319/7321/56852/7320/7336/7323/7316/5111/7415/7322/118424/7324/6233/7311/7334/3105/6596/7314 19 Marburg_virus R-HSA-8854691 Interleukin-20 family signaling 11/1454 25/10654 2.084679308288205e-4 8.385339454104953e-4 4.81646102167142e-4 6775/6776/6774/3718/6772/3717/3716/6777/6773/7297/5781 11 Marburg_virus R-HSA-9006115 Signaling by NTRK2 (TRKB) 11/1454 25/10654 2.084679308288205e-4 8.385339454104953e-4 4.81646102167142e-4 5295/4893/5335/10817/6714/2534/2885/3845/3265/5781/5879 11 Marburg_virus R-HSA-5205647 Mitophagy 12/1454 29/10654 2.1842441354337196e-4 8.730042433368422e-4 5.014455208163626e-4 9140/8878/9474/192111/7316/1457/6714/81631/6233/7311/84557/7314 12 Marburg_virus R-HSA-72086 mRNA Capping 12/1454 29/10654 2.1842441354337196e-4 8.730042433368422e-4 5.014455208163626e-4 5430/404672/4686/2966/8731/5437/2965/2068/2071/2968/2967/22916 12 Marburg_virus R-HSA-202403 TCR signaling 31/1454 119/10654 2.200319880559825e-4 8.738809872633501e-4 5.019491143764236e-4 5295/8454/1147/5170/8945/5335/4790/6885/4690/7321/6500/5788/8517/7316/7335/5970/4792/7322/23291/5728/1445/7189/6233/3702/7311/3932/5296/7334/3551/997/7314 31 Marburg_virus R-HSA-9612973 Autophagy 31/1454 119/10654 2.200319880559825e-4 8.738809872633501e-4 5.019491143764236e-4 2670/9140/22863/8878/1080/10533/10013/9474/192111/7316/1457/8678/6714/3920/3320/6009/55054/81631/6233/2475/55004/7311/84557/200894/55626/7251/7431/3312/57521/7314/28956 31 Marburg_virus R-HSA-211000 Gene Silencing by RNA 34/1454 136/10654 2.6210086774608503e-4 0.0010376886556362297 5.960387161256551e-4 23165/27161/81929/5903/55706/7175/9631/5430/27327/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/5437/23225/3320/5901/8086/9972/8021/6396/129401/55746/23405/8480/10526 34 Marburg_virus R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 29/1454 110/10654 2.783926182695903e-4 0.0010987345028257497 6.311028831915806e-4 11065/4790/246184/1029/7321/8697/1027/8881/7316/6774/5970/1026/51433/51529/7324/64682/29945/10393/6233/51434/2353/51343/6196/7311/29882/3569/7314/996/5595 29 Marburg_virus R-HSA-2500257 Resolution of Sister Chromatid Cohesion 32/1454 126/10654 2.896596917948022e-4 0.001139629849905175 6.545927903389116e-4 5905/81929/5903/55143/9735/991/9212/3619/23244/348995/79023/9133/10381/57122/332/23047/891/5501/983/23279/79902/1062/7846/347733/22919/10376/7514/10383/5347/6396/55746/7280 32 Marburg_virus R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 8/1454 15/10654 3.1095167543151834e-4 0.0012158017371685765 6.983452141923932e-4 6737/29110/7316/22954/3661/6233/7311/7314 8 Marburg_virus R-HSA-844456 The NLRP3 inflammasome 8/1454 15/10654 3.1095167543151834e-4 0.0012158017371685765 6.983452141923932e-4 834/351/4790/10910/29108/5970/114548/4791 8 Marburg_virus R-HSA-9607240 FLT3 Signaling 57/1454 267/10654 3.1330873106344046e-4 0.0012212250538974352 7.014603168994087e-4 5295/54106/5170/2674/4893/1437/3667/3561/5747/3815/7010/1439/2322/409/5908/10817/2064/5921/8452/6776/4684/7316/9978/3560/4233/84078/3718/6714/2261/3558/3717/2534/408/1445/1847/3563/1739/6233/2885/3716/8660/7311/5155/1956/4254/5296/4140/3845/6777/3265/3559/369/5781/7529/7314/28956/5595 57 Marburg_virus R-HSA-114452 Activation of BH3-only proteins 12/1454 30/10654 3.192035941865051e-4 0.0012403621144469444 7.124524665566244e-4 10018/7531/7027/7532/10971/7533/2810/7534/7157/8626/5599/7529 12 Marburg_virus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 22/1454 76/10654 3.648053163197446e-4 0.0014131996715278721 8.117287524264438e-4 11065/246184/7321/991/8697/8881/7316/891/983/51433/51529/7324/64682/29945/10393/6233/51434/7311/5347/29882/7314/996 22 Marburg_virus R-HSA-389359 CD28 dependent Vav1 pathway 7/1454 12/10654 3.672641310907807e-4 0.0014183605553475243 8.146931161103207e-4 2534/998/942/2885/7409/3932/5879 7 Marburg_virus R-HSA-6804760 Regulation of TP53 Activity through Methylation 9/1454 19/10654 4.070470198393727e-4 0.001567193265987065 9.001812413637503e-4 11200/472/7316/2033/7157/6233/7311/7314/4193 9 Marburg_virus R-HSA-8953750 Transcriptional Regulation by E2F6 13/1454 35/10654 4.279608200452076e-4 0.0016426910745027939 9.435464806516611e-4 23468/5888/7027/2146/8317/6045/80012/1911/5928/1111/672/7703/6015 13 Marburg_virus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 21/1454 72/10654 4.3995447033462107e-4 0.0016835947664172886 9.670411809946717e-4 11065/246184/7321/8697/898/8881/7316/51433/990/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/7314/996 21 Marburg_virus R-HSA-5693606 DNA Double Strand Break Response 22/1454 77/10654 4.460232356721398e-4 0.0017003795872002803 9.766822259994084e-4 25/3838/51588/11200/472/7336/580/7316/9656/7341/165918/7157/7329/8924/6233/672/7158/7311/9025/5599/7334/7314 22 Marburg_virus R-HSA-2871837 FCERI mediated NF-kB activation 23/1454 82/10654 4.4704181363248036e-4 0.0017003795872002803 9.766822259994084e-4 8454/1147/5170/8945/4790/6885/7321/6500/8517/7316/7335/5970/4792/7322/4067/23291/7189/6233/7311/7334/3551/997/7314 23 Marburg_virus R-HSA-112409 RAF-independent MAPK1/3 activation 10/1454 23/10654 4.568834705804913e-4 0.0017325791851230076 9.951773756778615e-4 983/3717/1847/3716/3570/7297/5781/3569/3572/5595 10 Marburg_virus R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 11/1454 27/10654 4.6963100557972687e-4 0.001775571879954583 0.0010198719798744187 7186/219699/8737/841/7099/836/8837/8772/26060/8743/148022 11 Marburg_virus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 27/1454 103/10654 4.91232219169412e-4 0.0018516807303421846 0.0010635881959325118 5295/3643/3667/3815/2064/4615/2100/4233/6714/8503/2261/2534/3630/942/7189/2885/7409/8660/3932/5155/1956/4254/5296/5781/5879/5595/3556 27 Marburg_virus R-HSA-202424 Downstream TCR signaling 26/1454 98/10654 5.076013599348105e-4 0.001907671976590825 0.0010957490472119867 5295/8454/1147/5170/8945/4790/6885/7321/6500/8517/7316/7335/5970/4792/7322/23291/5728/7189/6233/7311/3932/5296/7334/3551/997/7314 26 Marburg_virus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 19/1454 63/10654 5.124629311608957e-4 0.001920210804558237 0.0011029512334195968 11065/246184/7321/8697/8881/7316/51433/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/7314/996 19 Marburg_virus R-HSA-5654738 Signaling by FGFR2 21/1454 73/10654 5.395528738481836e-4 0.002011321469792428 0.0011552843524496453 5295/4893/5335/5430/3178/10817/4686/7316/6714/867/5437/7072/6233/2885/7311/3845/3265/5781/22916/7314/5595 21 Marburg_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 23/1454 83/10654 5.399735161158386e-4 0.002011321469792428 0.0011552843524496453 8454/1147/8945/4893/4773/4790/6885/5579/5966/6500/8517/7316/5970/4792/4793/23291/5478/6233/7311/3845/3265/3551/7314 23 Marburg_virus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 8/1454 16/10654 5.47738477202309e-4 0.002028243361169727 0.0011650041295293693 57154/5590/7316/7046/6233/7311/56288/7314 8 Marburg_virus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 8/1454 16/10654 5.47738477202309e-4 0.002028243361169727 0.0011650041295293693 6885/7099/7316/7189/6233/7311/7314/148022 8 Marburg_virus R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 13/1454 36/10654 5.87106022369509e-4 0.002167643642707366 0.0012450743552025088 26999/25/5747/4690/10006/10458/10152/998/2885/10096/10787/5879/5595 13 Marburg_virus R-HSA-69206 G1/S Transition 32/1454 131/10654 6.071616879801814e-4 0.002235136155459206 0.0012838414270310394 8454/6118/5000/7027/8317/1027/6500/898/4173/7316/5422/891/5753/993/983/1026/5111/4171/4609/6119/5928/6502/990/4175/3065/6233/7311/6117/5001/7083/4176/7314 32 Marburg_virus R-HSA-69190 DNA strand elongation 12/1454 32/10654 6.409612969295861e-4 0.0023458438163789213 0.001347430878184289 6118/2237/1763/4173/5422/5111/4171/6119/4175/6117/5981/4176 12 Marburg_virus R-HSA-8941326 RUNX2 regulates bone development 12/1454 32/10654 6.409612969295861e-4 0.0023458438163789213 0.001347430878184289 25/3280/100526737/10013/865/9759/10413/6714/23314/7525/25937/5595 12 Marburg_virus R-HSA-199418 Negative regulation of the PI3K/AKT network 28/1454 110/10654 6.500296842732688e-4 0.0023619505576791184 0.0013566824406383965 5295/3643/3667/3815/2064/4615/2100/4233/6714/8503/2261/2534/5728/3630/942/7189/2885/7409/8660/3932/5155/1956/4254/5296/5781/5879/5595/3556 28 Marburg_virus R-HSA-167044 Signalling to RAS 9/1454 20/10654 6.509903443325291e-4 0.0023619505576791184 0.0013566824406383965 4893/6714/7867/4914/2885/5900/3845/5600/3265 9 Marburg_virus R-HSA-622312 Inflammasomes 9/1454 20/10654 6.509903443325291e-4 0.0023619505576791184 0.0013566824406383965 834/9447/351/4790/10910/29108/5970/114548/4791 9 Marburg_virus R-HSA-202733 Cell surface interactions at the vascular wall 33/1454 137/10654 6.559177605468952e-4 0.0023729898291050032 0.0013630232955103357 5295/3675/5777/4893/857/5335/960/483/5175/3684/7010/4680/3678/3688/8140/6714/4067/682/2534/1088/5478/6520/2885/7525/3685/3932/5296/3687/3845/3265/5781/6566/3655 33 Marburg_virus R-HSA-8940973 RUNX2 regulates osteoblast differentiation 10/1454 24/10654 6.881873130842813e-4 0.0024826012239917198 0.0014259830616465126 25/3280/10013/865/10413/6714/23314/7525/25937/5595 10 Marburg_virus R-HSA-171007 p38MAPK events 7/1454 13/10654 7.021335596309789e-4 0.0025113242942483025 0.001442481326155749 4893/6714/7867/5900/3845/5600/3265 7 Marburg_virus R-HSA-2995383 Initiation of Nuclear Envelope Reformation 7/1454 13/10654 7.021335596309789e-4 0.0025113242942483025 0.001442481326155749 4000/23141/7444/2010/4001/23592/7112 7 Marburg_virus R-HSA-2995410 Nuclear Envelope Reassembly 7/1454 13/10654 7.021335596309789e-4 0.0025113242942483025 0.001442481326155749 4000/23141/7444/2010/4001/23592/7112 7 Marburg_virus R-HSA-388841 Costimulation by the CD28 family 20/1454 70/10654 7.978066296781794e-4 0.0028324805554561425 0.0016269504967170016 5295/5170/5777/5133/6714/8503/4067/2534/1445/998/942/2885/7525/2475/7409/3932/5296/5781/5879/253260 20 Marburg_virus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 21/1454 75/10654 7.986740247711919e-4 0.0028324805554561425 0.0016269504967170016 11065/246184/7321/991/8697/8881/7316/891/983/51433/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 21 Marburg_virus R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 21/1454 75/10654 7.986740247711919e-4 0.0028324805554561425 0.0016269504967170016 5295/3667/3815/2064/2100/4233/6714/8503/2261/2534/942/2885/7409/8660/3932/5155/1956/4254/5296/5781/5879 21 Marburg_virus R-HSA-174437 Removal of the Flap Intermediate from the C-strand 6/1454 10/10654 8.209060951636606e-4 0.002862938431609553 0.0016444452176044171 6118/2237/1763/5111/6119/6117 6 Marburg_virus R-HSA-390450 Folding of actin by CCT/TriC 6/1454 10/10654 8.209060951636606e-4 0.002862938431609553 0.0016444452176044171 10694/7203/10576/908/10574/10693 6 Marburg_virus R-HSA-5602498 MyD88 deficiency (TLR2/4) 6/1454 10/10654 8.209060951636606e-4 0.002862938431609553 0.0016444452176044171 10333/7099/4615/7096/114609/7097 6 Marburg_virus R-HSA-74749 Signal attenuation 6/1454 10/10654 8.209060951636606e-4 0.002862938431609553 0.0016444452176044171 3643/3667/3630/2885/8660/5595 6 Marburg_virus R-HSA-8853334 Signaling by FGFR3 fusions in cancer 6/1454 10/10654 8.209060951636606e-4 0.002862938431609553 0.0016444452176044171 5295/4893/2261/2885/3845/3265 6 Marburg_virus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 6/1454 10/10654 8.209060951636606e-4 0.002862938431609553 0.0016444452176044171 6885/7316/7189/6233/7311/7314 6 Marburg_virus R-HSA-8878159 Transcriptional regulation by RUNX3 25/1454 96/10654 8.673589731247716e-4 0.0030165882518344957 0.0017327002458177318 57154/1499/10018/1029/3280/64750/7316/865/9759/1026/10413/6714/4609/22938/1387/2033/7157/861/6233/7311/25937/3845/4851/7314/4193 25 Marburg_virus R-HSA-1980145 Signaling by NOTCH2 12/1454 33/10654 8.835827922777203e-4 0.003047755439664794 0.0017506023887376894 142678/3280/23385/7316/102/2033/3002/4853/6233/7311/5663/7314 12 Marburg_virus R-HSA-2559585 Oncogene Induced Senescence 12/1454 33/10654 8.835827922777203e-4 0.003047755439664794 0.0017506023887376894 1029/7027/27327/7316/6667/7157/6233/7311/4343/7314/5595/4193 12 Marburg_virus R-HSA-68962 Activation of the pre-replicative complex 12/1454 33/10654 8.835827922777203e-4 0.003047755439664794 0.0017506023887376894 6118/5000/8317/4173/5422/4171/6119/990/4175/6117/5001/4176 12 Marburg_virus R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 8/1454 17/10654 9.114733951070278e-4 0.003118328816412359 0.001791139080201739 7186/8737/841/7099/8837/8772/8743/148022 8 Marburg_virus R-HSA-8934593 Regulation of RUNX1 Expression and Activity 8/1454 17/10654 9.114733951070278e-4 0.003118328816412359 0.001791139080201739 27161/27327/865/6714/861/5371/4343/5781 8 Marburg_virus R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 8/1454 17/10654 9.114733951070278e-4 0.003118328816412359 0.001791139080201739 6885/7099/7316/7189/6233/7311/7314/148022 8 Marburg_virus R-HSA-432722 Golgi Associated Vesicle Biogenesis 17/1454 56/10654 9.15265584661151e-4 0.0031228167238167726 0.0017937168924895472 27131/2512/9685/10618/6272/8546/2804/7037/3482/408/5878/6844/6845/64746/3312/8673/1362 17 Marburg_virus R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 18/1454 61/10654 9.485810984222929e-4 0.0032277394673342345 0.0018539835408708822 26999/25/5747/4690/10006/10458/4771/10152/3320/998/2885/1398/7410/10096/7409/10787/5879/5595 18 Marburg_virus R-HSA-5218920 VEGFR2 mediated vascular permeability 11/1454 29/10654 9.604748600667912e-4 0.003259401209768437 0.0018721697513573148 5170/857/1495/1499/1500/3320/7410/2475/7409/5879/253260 11 Marburg_virus R-HSA-5693565 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 21/1454 76/10654 9.643329861799341e-4 0.0032636968537648843 0.001874637129331111 25/51588/11200/472/7336/580/7316/9656/7341/165918/7157/7329/8924/6233/672/7158/7311/9025/5599/7334/7314 21 Marburg_virus R-HSA-983231 Factors involved in megakaryocyte development and platelet production 38/1454 168/10654 9.797944328817955e-4 0.003300450284115605 0.0018957479580179932 3443/23468/25/3441/11311/5868/23186/10019/10381/3449/3444/3659/2627/1062/3451/5889/3717/7846/5576/3448/347733/10376/3440/3066/3065/998/7157/23028/3835/10383/3452/5890/3456/10938/7280/3446/5879/3445 38 Marburg_virus R-HSA-5663220 RHO GTPases Activate Formins 33/1454 140/10654 9.804355887682577e-4 0.003300450284115605 0.0018957479580179932 5905/81929/5903/55143/9735/991/9212/389/3619/348995/79023/10381/57122/332/3688/5501/5216/6714/23279/79902/1062/7846/347733/22919/10376/998/7514/10383/5347/6396/55746/7280/5879 33 Marburg_virus R-HSA-445144 Signal transduction by L1 9/1454 21/10654 0.0010023155290807605 0.003365107336300473 0.0019328863676588979 3678/4684/3688/1457/7410/3685/1956/5879/5595 9 Marburg_virus R-HSA-210991 Basigin interactions 10/1454 25/10654 0.0010080002345879237 0.003375192274856904 0.0019386790626033134 3675/857/483/3688/8140/682/5478/6520/6566/3655 10 Marburg_virus R-HSA-111465 Apoptotic cleavage of cellular proteins 13/1454 38/10654 0.0010573368989756095 0.0035310004132899 0.0020281738087288667 4000/1499/5747/118/1829/841/100506658/5339/836/4001/6093/7431/6304 13 Marburg_virus R-HSA-2428928 IRS-related events triggered by IGF1R 16/1454 52/10654 0.0010923899388085515 0.0036384098755554667 0.0020898688052394176 5295/54106/5170/4893/3667/2322/2261/8471/2885/8660/3479/5296/3845/3265/5781/3480 16 Marburg_virus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 20/1454 72/10654 0.0011749267897073709 0.0038927179690567896 0.002235941009775523 11065/246184/7321/991/8697/8881/7316/983/51433/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 20 Marburg_virus R-HSA-199992 trans-Golgi Network Vesicle Budding 20/1454 72/10654 0.0011749267897073709 0.0038927179690567896 0.002235941009775523 27131/8773/2512/351/9685/10618/6272/8546/2804/7037/9146/3482/408/5878/6844/6845/64746/3312/8673/1362 20 Marburg_virus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 19/1454 67/10654 0.0011793361575368852 0.0038970714497085003 0.0022384416085863795 11065/246184/7321/991/8697/8881/7316/51433/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 19 Marburg_virus R-HSA-2172127 DAP12 interactions 14/1454 43/10654 0.0011956410424720464 0.003940607519561012 0.002263448322343058 5295/4893/5335/7305/567/2534/22914/2885/7410/3932/5296/3845/3265/5879 14 Marburg_virus R-HSA-2559580 Oxidative Stress Induced Senescence 30/1454 125/10654 0.0012019529500147054 0.003951067269108392 0.002269456305235956 1912/1029/7027/2146/8535/6045/27327/80012/7316/1911/7867/5928/84733/57332/7157/23135/5609/6233/2353/7311/4343/5599/5600/4217/3456/7314/6015/5595/4193/23043 30 Marburg_virus R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 7/1454 14/10654 0.0012394657630756317 0.004042713460394353 0.0023220970254512105 5861/9133/891/26003/983/5347/5595 7 Marburg_virus R-HSA-69166 Removal of the Flap Intermediate 7/1454 14/10654 0.0012394657630756317 0.004042713460394353 0.0023220970254512105 6118/2237/1763/5422/5111/6119/6117 7 Marburg_virus R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 7/1454 14/10654 0.0012394657630756317 0.004042713460394353 0.0023220970254512105 4893/5921/5753/1398/3845/3265/5879 7 Marburg_virus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 23/1454 88/10654 0.00130120494364496 0.004233118925191227 0.0024314641541794847 8454/8945/7531/203068/7532/6500/9133/7316/891/983/10121/23291/7846/7283/3320/22919/1069/6233/7311/10383/5347/55755/7314 23 Marburg_virus R-HSA-180786 Extension of Telomeres 11/1454 30/10654 0.001331737171892217 0.004321281184052323 0.002482103736000958 6118/2237/7015/1763/5422/10856/5111/6119/8607/6117/5981 11 Marburg_virus R-HSA-2428924 IGF1R signaling cascade 16/1454 53/10654 0.0013698703668230993 0.00443359072449944 0.0025466132918616404 5295/54106/5170/4893/3667/2322/2261/8471/2885/8660/3479/5296/3845/3265/5781/3480 16 Marburg_virus R-HSA-68877 Mitotic Prometaphase 43/1454 200/10654 0.0014065347062701594 0.004540582551779823 0.002608068402719567 10844/5905/81929/5903/55143/9735/7531/991/203068/7532/9212/3619/23244/348995/79023/9133/10381/57122/332/23047/891/5501/1457/983/23279/10121/79902/1062/7846/7283/347733/3320/22919/10376/1069/7514/10383/5347/6396/27229/55746/7280/55755 43 Marburg_virus R-HSA-917937 Iron uptake and transport 17/1454 58/10654 0.0014127448491885845 0.004543610661250412 0.0026098077206463217 8454/2512/55240/4738/6500/7036/7316/527/525/23545/7037/55832/6233/7311/26234/7314/9296 17 Marburg_virus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 20/1454 73/10654 0.0014146905315410338 0.004543610661250412 0.0026098077206463217 11065/246184/7321/991/8697/8881/7316/983/51433/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 20 Marburg_virus R-HSA-210993 Tie2 Signaling 8/1454 18/10654 0.0014457639819064887 0.004619839728985455 0.002653592988431092 5295/4893/7010/2885/5296/3845/3265/5781 8 Marburg_virus R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 8/1454 18/10654 0.0014457639819064887 0.004619839728985455 0.002653592988431092 4893/5578/2885/6196/1956/3845/3265/5595 8 Marburg_virus R-HSA-2979096 NOTCH2 Activation and Transmission of Signal to the Nucleus 9/1454 22/10654 0.0014927154577990592 0.004733825595387949 0.0027190654103352876 142678/23385/7316/102/4853/6233/7311/5663/7314 9 Marburg_virus R-HSA-389357 CD28 dependent PI3K/Akt signaling 9/1454 22/10654 0.0014927154577990592 0.004733825595387949 0.0027190654103352876 5295/5170/8503/2534/942/2475/3932/5296/253260 9 Marburg_virus R-HSA-5205685 Pink/Parkin Mediated Mitophagy 9/1454 22/10654 0.0014927154577990592 0.004733825595387949 0.0027190654103352876 9140/8878/9474/7316/81631/6233/7311/84557/7314 9 Marburg_virus R-HSA-174414 Processive synthesis on the C-strand of the telomere 6/1454 11/10654 0.0015978167756090155 0.00495480620810776 0.002845994619765086 6118/2237/1763/5111/6119/6117 6 Marburg_virus R-HSA-3371378 Regulation by c-FLIP 6/1454 11/10654 0.0015978167756090155 0.00495480620810776 0.002845994619765086 7186/8737/841/8837/8772/8743 6 Marburg_virus R-HSA-5218900 CASP8 activity is inhibited 6/1454 11/10654 0.0015978167756090155 0.00495480620810776 0.002845994619765086 7186/8737/841/8837/8772/8743 6 Marburg_virus R-HSA-5603041 IRAK4 deficiency (TLR2/4) 6/1454 11/10654 0.0015978167756090155 0.00495480620810776 0.002845994619765086 10333/7099/4615/7096/114609/7097 6 Marburg_virus R-HSA-5655291 Signaling by FGFR4 in disease 6/1454 11/10654 0.0015978167756090155 0.00495480620810776 0.002845994619765086 5295/4893/5335/2885/3845/3265 6 Marburg_virus R-HSA-69416 Dimerization of procaspase-8 6/1454 11/10654 0.0015978167756090155 0.00495480620810776 0.002845994619765086 7186/8737/841/8837/8772/8743 6 Marburg_virus R-HSA-8875555 MET activates RAP1 and RAC1 6/1454 11/10654 0.0015978167756090155 0.00495480620810776 0.002845994619765086 5908/4233/2885/1398/1399/5879 6 Marburg_virus R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 6/1454 11/10654 0.0015978167756090155 0.00495480620810776 0.002845994619765086 4893/10817/2885/3845/3265/5781 6 Marburg_virus R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 6/1454 11/10654 0.0015978167756090155 0.00495480620810776 0.002845994619765086 6885/7316/7189/6233/7311/7314 6 Measles_virus R-HSA-983169 Class I MHC mediated antigen processing & presentation 336/2735 371/10654 5.54954228246614e-161 7.602872926978612e-158 3.8321049866292505e-158 8454/9354/23643/57154/1147/3135/5718/197131/23352/5689/26224/8945/4688/10293/51088/140460/5684/79754/6737/8065/64410/127544/114088/5720/11065/285231/221687/9666/10952/84937/57531/142678/55070/5682/84708/246184/146330/55819/51320/93611/7319/54850/142686/8916/79791/26046/151636/5700/3107/122706/7321/5707/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/10484/8697/7320/5690/26235/10477/9817/10193/6890/148581/55176/9039/223082/92912/154881/5717/140739/821/25897/9491/6500/23198/6478/150726/390594/811/10533/81559/143471/144699/5706/140462/6892/5705/26259/57674/51130/10333/10197/7099/53339/8517/154214/7336/200845/4615/79876/26263/64750/51619/6477/9690/23480/8881/8452/7326/23376/6049/7323/6891/10517/57630/54778/89890/142689/7316/10213/5709/9604/9978/22888/5695/23304/29927/7317/80196/114907/140456/64718/54926/4008/7335/7096/84861/11059/567/55236/84085/55958/54620/4734/84078/7337/5714/26272/84676/140691/27252/51444/7704/8651/3106/3093/26118/222235/51433/9861/25831/7322/5715/64219/10489/5711/23327/9867/26249/140458/55905/5701/5688/10134/55336/5687/26270/143279/51465/63893/89122/6502/23291/118424/5685/10616/5683/929/3309/5698/5708/27246/5692/5686/89910/5713/55521/114609/25898/9903/201456/55294/5699/26190/55008/2923/7328/79654/5710/10422/84727/135892/7428/5702/22954/8453/401036/83737/51529/9040/695/90933/140461/7324/63891/5719/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/5704/6233/90135/56658/9870/51434/6468/26267/948/142685/1520/4012/5716/25847/90025/7327/3685/10425/25793/51343/7311/26091/23295/6047/84541/3133/7318/23194/51666/90293/131405/55175/55284/3134/868/54461/9320/136371/80204/26232/29882/57520/26234/6396/127247/27338/92591/7334/5930/11275/55182/5694/7097/84961/4591/3551/23014/29116/26268/92369/1536/115290/90678/51725/140459/3105/5693/5721/5696/997/23608/51676/55585/64320/5691/51132/84261/7325/57542/9820/55658/7314/996/4360/10324/283807/1514/899 336 Measles_virus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 296/2735 309/10654 5.599474110238558e-160 3.835639765513412e-157 1.9332921138507864e-157 8454/9354/57154/5718/197131/23352/5689/26224/8945/10293/51088/140460/5684/79754/6737/8065/64410/127544/114088/5720/11065/285231/221687/9666/84937/57531/142678/55070/5682/84708/246184/146330/55819/51320/93611/7319/54850/142686/8916/79791/26046/151636/5700/122706/7321/5707/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/8697/7320/5690/26235/10477/9817/10193/148581/9039/223082/92912/154881/5717/140739/25897/9491/6500/23198/6478/150726/390594/10533/81559/143471/144699/5706/140462/5705/26259/57674/51130/10197/53339/154214/7336/200845/79876/26263/64750/51619/6477/9690/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/10213/5709/9604/9978/22888/5695/23304/7317/80196/114907/140456/64718/54926/4008/7335/84861/11059/55236/84085/55958/54620/4734/84078/7337/5714/26272/84676/140691/27252/51444/7704/8651/3093/26118/222235/51433/9861/25831/7322/5715/64219/10489/5711/23327/9867/26249/140458/55905/5701/5688/55336/5687/26270/143279/51465/63893/89122/6502/23291/118424/5685/10616/5683/5698/5708/27246/5692/5686/89910/5713/55521/25898/9903/201456/55294/5699/26190/55008/7328/79654/5710/10422/84727/135892/7428/5702/22954/8453/401036/83737/51529/9040/90933/140461/7324/63891/5719/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/5704/6233/90135/56658/9870/51434/6468/26267/142685/4012/5716/25847/90025/7327/10425/25793/51343/7311/26091/23295/6047/84541/7318/23194/51666/90293/131405/55175/55284/868/54461/9320/136371/80204/26232/29882/57520/26234/127247/27338/92591/7334/5930/11275/55182/5694/84961/4591/23014/29116/26268/92369/115290/90678/51725/140459/5693/5721/5696/997/23608/51676/55585/64320/5691/51132/84261/7325/57542/9820/55658/7314/996/10324/283807/899 296 Measles_virus R-HSA-8951664 Neddylation 208/2735 234/10654 6.209964890677666e-95 2.8358839667428008e-92 1.4293813923805432e-92 8454/9318/5718/51397/5689/26224/54165/8945/56995/23412/51088/9655/140460/5684/79754/8065/64410/5720/149951/29099/285231/23363/5682/23038/146330/80344/25879/93611/54850/142686/55884/79791/5700/122706/7321/5707/51665/9616/122769/9021/4738/5690/26235/9817/9039/154881/5717/140739/5929/9491/6500/23198/5931/150726/390594/143471/144699/5706/140462/28952/5705/26259/51130/10197/53339/28991/200845/332/26263/140825/8452/8450/7323/9306/10517/89890/142689/7316/10213/5709/9978/5695/114907/140456/4008/84861/64708/84085/55958/54620/84078/5714/55527/26272/27252/7704/26118/222235/10980/9861/7322/5715/122416/10489/5711/26249/140458/5701/5688/55336/5687/26270/6502/7347/23291/170622/5685/90864/5683/55832/5698/5708/1642/5692/10920/5686/5713/9903/201456/55294/5699/26190/10238/5710/84727/10987/7428/5702/8453/123879/401036/9040/140461/5719/79176/80176/8139/23142/126433/10116/5704/6233/90135/6468/2873/26267/142685/5716/25793/7311/1154/84541/23194/83987/51666/90293/55175/8533/54461/136371/80204/26232/8835/26234/127247/8883/92591/11275/5694/51122/84961/54939/23014/26268/92369/115290/54951/51725/140459/5693/55208/5721/84259/5696/51676/5691/84261/150684/50813/57542/9820/7314/51138/10324/8451/56929/283807/899 208 Measles_virus R-HSA-68886 M Phase 277/2735 395/10654 1.1734509432085883e-79 4.019069480489415e-77 2.025746891433773e-77 114791/10844/115106/5718/23165/220134/4926/5689/5905/55839/11130/22995/55559/26271/79682/5684/5903/10403/5720/11065/54908/440145/55706/7175/6249/55143/11258/5682/64151/22981/9631/246184/55055/25936/5525/9735/8636/7531/10142/80776/1783/1058/5700/11190/122706/7321/5707/991/91754/401541/203068/79019/5526/54801/7532/5862/55125/1454/348235/2801/80152/8697/5690/10382/9212/5594/1063/8379/95681/5717/3619/9491/140609/23198/79172/10274/5861/5925/121441/147841/23244/7277/348995/23421/79441/143471/79023/55920/5706/9133/10381/57122/5705/23636/79980/64105/10735/5116/23310/10197/6232/332/23047/1780/10762/8881/9814/653784/10051/5885/23122/23511/5528/5048/1781/23354/7316/10213/5709/80321/891/5695/5501/53371/26003/57405/8655/4085/9738/983/1639/8548/5714/55722/4957/23279/4927/9688/55166/10121/51433/9861/79902/9702/5566/3796/8615/5715/79959/54821/5519/84131/81876/5711/9183/9883/81565/5701/2491/5688/10112/1062/699/5687/7846/23225/7840/5685/7283/5683/5698/5708/3320/22919/5692/5686/5713/80097/1060/91687/119504/79003/8243/9126/10426/5699/23397/5529/5710/22994/11064/51143/9918/5702/10540/10733/51529/85378/1069/8086/7324/83540/5719/64682/29945/10393/4751/11004/9232/5577/5704/6233/5527/9700/51434/27175/80254/5716/701/7514/7311/9184/54930/9972/5518/25906/55844/10383/55835/54820/5347/113130/57551/54892/29922/8021/84643/9493/29882/6396/129401/9662/80184/55142/5694/23332/84930/1453/22897/25909/27229/64689/64946/9793/10726/5108/81930/55746/8481/7112/5693/5721/140735/93323/5696/10592/10806/55755/5691/29781/8480/7314/996/5595/5515/1778/5516 277 Measles_virus R-HSA-69275 G2/M Transition 171/2735 196/10654 4.427502956825836e-75 1.213135810170279e-72 6.114614609847891e-73 114791/10844/8454/115106/5718/1017/5689/8945/22995/55559/5684/994/5720/4605/440145/2305/11258/5682/22981/8636/7531/51512/10142/4659/5700/11190/122706/5707/203068/54801/7532/84962/55125/1454/22974/5690/10382/3161/1063/95681/5717/9491/6500/23198/121441/7277/79441/143471/5706/9133/10381/5705/5116/10197/286826/9814/653784/5048/1781/23354/7316/10213/728642/5709/80321/9978/891/993/5695/890/8655/9738/983/1026/1639/6790/5714/55722/4957/10121/9861/9702/5566/5715/79959/5519/84131/9088/5711/5928/5701/5688/5687/91750/23291/7846/7840/5685/7283/5683/5698/5708/3320/22919/5692/984/5686/5713/80097/2033/995/10426/5699/5710/22994/11064/5702/10540/7157/10733/8900/85378/79866/1069/5719/4751/5577/5704/6233/3326/27175/80254/5716/55957/7514/7311/54930/23194/5518/10133/10383/55835/54820/5347/29922/9662/80184/55142/5694/23332/1453/22897/7465/27229/9793/4218/5108/8481/5693/5721/93323/5696/132660/10806/55755/5691/5500/7314/5515/1778/5516 171 Measles_virus R-HSA-453274 Mitotic G2-G2/M phases 172/2735 198/10654 7.159326600483507e-75 1.634712907110401e-72 8.239505701609089e-73 114791/10844/8454/115106/5718/1017/5689/8945/22995/55559/5684/994/5720/4605/440145/2305/11258/5682/22981/8636/7531/51512/10142/4659/5700/11190/122706/5707/203068/54801/7532/84962/55125/1454/22974/5690/10382/3161/1063/95681/5717/9491/6500/23198/121441/7277/79441/143471/5706/9133/10381/5705/5116/10197/286826/9814/653784/5048/1781/23354/7316/10213/728642/5709/80321/9978/1869/891/993/5695/890/8655/9738/983/1026/1639/6790/5714/55722/4957/10121/9861/9702/5566/5715/79959/5519/84131/9088/5711/5928/5701/5688/5687/91750/23291/7846/7840/5685/7283/5683/5698/5708/3320/22919/5692/984/5686/5713/80097/2033/995/10426/5699/5710/22994/11064/5702/10540/7157/10733/8900/85378/79866/1069/5719/4751/5577/5704/6233/3326/27175/80254/5716/55957/7514/7311/54930/23194/5518/10133/10383/55835/54820/5347/29922/9662/80184/55142/5694/23332/1453/22897/7465/27229/9793/4218/5108/8481/5693/5721/93323/5696/132660/10806/55755/5691/5500/7314/5515/1778/5516 172 Measles_virus R-HSA-68877 Mitotic Prometaphase 172/2735 200/10654 2.1562113080294105e-73 4.220013560000418e-71 2.1270295008530724e-71 114791/10844/115106/220134/4926/5905/55839/11130/22995/55559/79682/5903/10403/54908/440145/6249/55143/11258/64151/22981/55055/25936/5525/9735/8636/7531/10142/80776/1783/1058/11190/991/401541/203068/79019/5526/54801/7532/55125/1454/348235/80152/10382/9212/1063/8379/95681/3619/79172/10274/121441/147841/23244/7277/348995/23421/79441/79023/55920/9133/10381/57122/79980/64105/10735/5116/6232/332/23047/1780/9814/653784/10051/5885/23122/5528/5048/1781/23354/80321/891/5501/57405/8655/4085/9738/983/1639/55722/4957/23279/55166/10121/79902/9702/5566/3796/79959/54821/5519/84131/9183/81565/2491/1062/699/7846/7840/7283/3320/22919/80097/1060/91687/79003/8243/9126/10426/23397/5529/22994/11064/51143/9918/10540/10733/85378/1069/83540/4751/11004/5577/5527/27175/80254/701/7514/9184/54930/5518/10383/55835/54820/5347/113130/57551/29922/84643/6396/9662/80184/55142/23332/1453/22897/25909/27229/64946/9793/10726/5108/81930/55746/8481/140735/93323/10592/10806/55755/5515/1778/5516 172 Measles_virus R-HSA-2467813 Separation of Sister Chromatids 166/2735 190/10654 4.328628457106985e-73 7.412776232795712e-71 3.73628982613445e-71 5718/220134/5689/5905/55839/11130/79682/5684/5903/10403/5720/11065/54908/6249/55143/5682/246184/55055/25936/5525/9735/80776/1783/1058/5700/122706/7321/5707/991/401541/79019/5526/348235/80152/8697/5690/10382/9212/1063/8379/5717/3619/9491/23198/79172/10274/147841/23244/7277/348995/23421/143471/79023/55920/5706/10381/57122/5705/79980/64105/10735/10197/6232/332/23047/1780/8881/5885/23122/5528/5048/1781/7316/10213/5709/5695/5501/57405/8655/4085/5714/23279/55166/51433/9861/79902/3796/5715/54821/5519/5711/9183/81565/5701/2491/5688/1062/699/5687/7846/5685/5683/5698/5708/22919/5692/5686/5713/1060/91687/119504/79003/8243/9126/5699/5529/5710/51143/5702/51529/7324/83540/5719/64682/29945/10393/11004/9232/5704/6233/5527/9700/51434/5716/701/7514/7311/9184/5518/25906/10383/54820/5347/113130/57551/84643/29882/6396/5694/23332/25909/64946/9793/10726/81930/55746/5693/5721/140735/5696/5691/7314/996/5515/1778/5516 166 Measles_virus R-HSA-2555396 Mitotic Metaphase and Anaphase 168/2735 202/10654 3.942540044254457e-67 6.001422067365118e-65 3.0249196129016648e-65 5718/220134/5689/5905/55839/11130/26271/79682/5684/5903/10403/5720/11065/54908/6249/55143/5682/246184/55055/25936/5525/9735/80776/1783/1058/5700/122706/7321/5707/991/401541/79019/5526/348235/80152/8697/5690/10382/9212/1063/8379/5717/3619/9491/23198/79172/10274/147841/23244/7277/348995/23421/143471/79023/55920/5706/10381/57122/5705/79980/64105/10735/10197/6232/332/23047/1780/8881/5885/23122/5528/5048/1781/7316/10213/5709/5695/5501/57405/8655/4085/5714/23279/55166/51433/9861/79902/3796/5715/54821/5519/5711/9183/81565/5701/2491/5688/1062/699/5687/7846/5685/5683/5698/5708/22919/5692/5686/5713/1060/91687/119504/79003/8243/9126/5699/5529/5710/51143/5702/51529/7324/83540/5719/64682/29945/10393/11004/9232/5704/6233/5527/9700/51434/5716/701/7514/7311/9184/5518/25906/10383/54820/5347/113130/57551/84643/29882/6396/5694/23332/25909/64946/9793/10726/81930/55746/7112/5693/5721/140735/5696/5691/7314/996/5515/1778/5516 168 Measles_virus R-HSA-68882 Mitotic Anaphase 167/2735 201/10654 1.335278893531306e-66 1.829332084137889e-64 9.220452149016175e-65 5718/220134/5689/5905/55839/11130/79682/5684/5903/10403/5720/11065/54908/6249/55143/5682/246184/55055/25936/5525/9735/80776/1783/1058/5700/122706/7321/5707/991/401541/79019/5526/348235/80152/8697/5690/10382/9212/1063/8379/5717/3619/9491/23198/79172/10274/147841/23244/7277/348995/23421/143471/79023/55920/5706/10381/57122/5705/79980/64105/10735/10197/6232/332/23047/1780/8881/5885/23122/5528/5048/1781/7316/10213/5709/5695/5501/57405/8655/4085/5714/23279/55166/51433/9861/79902/3796/5715/54821/5519/5711/9183/81565/5701/2491/5688/1062/699/5687/7846/5685/5683/5698/5708/22919/5692/5686/5713/1060/91687/119504/79003/8243/9126/5699/5529/5710/51143/5702/51529/7324/83540/5719/64682/29945/10393/11004/9232/5704/6233/5527/9700/51434/5716/701/7514/7311/9184/5518/25906/10383/54820/5347/113130/57551/84643/29882/6396/5694/23332/25909/64946/9793/10726/81930/55746/7112/5693/5721/140735/5696/5691/7314/996/5515/1778/5516 167 Measles_virus R-HSA-449147 Signaling by Interleukins 288/2735 461/10654 3.487518738703865e-65 4.343546065476632e-63 2.1892940598944836e-63 5295/729230/8454/3605/3557/7124/1147/5718/2308/834/5689/10148/3725/7291/5777/8945/1326/596/9655/5684/351/3635/6464/2208/3592/5290/5720/3566/1437/3667/1441/4790/6885/6597/2309/5682/90865/5291/1511/3561/5657/11213/3587/7412/5700/6351/3578/122706/7184/5707/10392/8767/3593/6775/207/50616/3684/9021/1849/7422/29110/5690/3553/2625/1230/1439/5594/9446/8878/3595/54472/5717/2919/821/9491/6500/23198/5743/941/23118/143471/4318/5706/3383/5705/301/9987/11009/10197/4478/8517/6657/1438/6778/53833/3576/4615/3581/7534/3313/332/3662/3597/6776/5528/3688/1436/2357/7316/3565/4985/10213/5709/9978/2920/3560/5695/6352/50615/3185/6774/1435/7335/5970/4792/3055/5443/6850/1026/6348/9261/59307/3718/1440/4793/3627/7133/5714/3606/177/6772/8651/4609/3146/6647/9861/5566/149233/6364/5715/5519/64127/8503/5711/7132/4988/5598/1901/3552/1432/5701/867/5688/5687/3558/4067/3717/23291/4088/3636/598/836/5685/5683/5698/5708/3320/5692/5686/5713/4843/2335/2534/3656/5306/5699/9466/5771/5710/3458/3181/10454/6288/5702/998/7157/5478/942/5719/3654/3563/7189/163702/6285/5704/6233/2885/7525/1398/58985/7006/948/6844/3716/5716/85480/7409/51135/8660/1385/2353/604/282618/7311/3594/53832/1154/6363/2939/6347/3932/3575/7076/5293/5518/2185/302/1386/5296/7040/3687/3588/51561/3570/6197/8835/5599/5600/5784/7431/6777/7334/5008/5694/3312/1399/3559/3929/3551/246778/55801/6773/7297/6416/5781/5608/3569/3162/5062/5693/3689/1234/5721/5696/3586/5691/4791/3554/5034/51231/7314/3572/3596/5595/5515/59067/257397/5516 288 Measles_virus R-HSA-69620 Cell Cycle Checkpoints 209/2735 293/10654 6.168790714749955e-62 7.042702732672865e-60 3.5497602709438333e-60 5718/1017/220134/4172/6118/5689/5905/55839/11130/79682/5684/5903/10403/5720/11065/54908/8318/6249/55143/5682/9156/246184/55055/25936/5525/9735/7531/51512/80776/1783/1058/5700/122706/7321/5707/991/401541/79019/5526/7532/8317/10971/348235/80152/8697/5690/9212/1063/51588/8379/5717/1027/3619/9491/23198/63967/79172/898/7533/2810/147841/348995/23421/4173/11200/143471/545/79023/55920/5706/9133/472/57122/5705/79980/64105/10197/7336/6232/7534/332/580/1780/8881/11073/29086/23122/5528/5048/1781/7316/10213/5709/4174/891/993/5695/5501/890/57405/8655/4085/983/1026/641/5714/4171/23279/55166/51433/9861/79902/3796/5715/54821/9656/5519/9088/6119/5711/9183/81565/5701/2491/5688/1062/699/5687/5685/5683/5698/5708/22919/5692/5686/990/5713/1060/91687/995/119504/79003/5699/5529/4175/5710/51143/1111/5702/7157/8900/51529/7324/83540/5719/64682/29945/10393/8924/11004/5704/6233/5527/51434/55388/5716/701/672/7514/5932/7158/23595/7311/9184/79184/5518/25906/54820/5347/57551/7156/84643/6117/29882/6396/7334/5694/23332/7465/25909/51230/64946/9793/10726/81930/55746/5693/5721/140735/5696/5691/4176/7529/7314/996/4193/5515/1778/5516 209 Measles_virus R-HSA-8957275 Post-translational protein phosphorylation 106/2735 108/10654 1.7739110398392443e-60 1.869429326599819e-58 9.422555806757443e-59 56955/4240/3371/3270/351/9210/8720/7018/2153/4052/10618/54587/11167/7184/7857/56975/813/5179/401138/3486/8074/7425/51246/334/29106/6383/91851/3912/348/3827/3490/338/6696/64856/4924/51156/3484/335/5589/5611/2621/1435/102/3915/8614/5768/1471/336/1462/6694/265/4148/10232/462/197/11098/3053/3698/174/57104/721/10130/5265/2335/1758/3895/2200/258/5624/80341/7466/375056/1000/54757/11320/8404/255738/3913/5954/652/116519/2266/51280/10272/57719/7076/147111/2243/1114/84141/213/2719/720/10117/3956/3569/10970/3488/8542/54972/5034/3487/1356/2519/4221/718 106 Measles_virus R-HSA-418594 G alpha (i) signalling events 257/2735 406/10654 1.0627547665768145e-59 1.0399814501501685e-57 5.241858096799927e-58 2788/729230/151/57007/10316/10803/2913/818/4544/4543/126006/10663/815/4889/3838/1880/7276/26086/9283/727/351/11251/7852/9294/54331/3352/8484/50833/29899/2339/338398/5726/117579/283869/338442/3579/59345/63940/4986/375790/23566/6351/2358/2916/64805/2770/6752/259293/6374/817/1237/5539/259287/1903/2852/2550/84539/50836/1230/5594/50832/5179/3354/6753/846/2841/4886/2919/3577/2918/51289/10681/5368/6754/8862/51764/259294/112/94235/114/259290/301/6383/8811/2912/108/3576/56670/5196/6360/348/3827/150/113/338/5173/56923/2832/5528/2357/4985/27199/2920/335/2826/55970/2921/2778/1236/2853/6352/140/6751/6376/259295/165140/27198/111/107/5443/9568/4836/186/10768/3627/53637/2792/54429/346562/6714/336/2840/2831/3361/6346/152/5566/6364/5367/80834/10563/5519/134/5540/4988/259292/1901/6370/58191/3949/2793/5030/5697/6755/1524/5733/256933/1129/643/10850/51083/2785/3355/2783/624/3351/2784/4035/4852/2782/1233/816/6288/6372/8601/6366/2786/50834/339403/2861/259285/2771/728/50838/5577/4023/2914/183/10022/5473/4283/5580/79823/8843/1385/719/2847/6363/6373/57121/4987/2917/2833/1268/9290/11255/50831/5518/9170/187/1132/2359/1814/10874/50839/83756/80835/6357/196883/6750/115/259296/2719/8698/259289/56477/5660/50835/801/1815/2587/1325/53829/1020/1232/9934/50840/1902/259286/3350/129521/1234/50837/2791/109/1269/59340/50865/4887/2773/2790/5515/718/2787/6387/623/5516 257 Measles_virus R-HSA-5620912 Anchoring of the basal body to the plasma membrane 95/2735 98/10654 1.4935821744731207e-52 1.3641383860187834e-50 6.875718641785032e-51 115106/22995/55559/79867/11258/22981/8636/7531/10142/54903/80776/11190/203068/54801/7532/55125/1454/10382/85302/51134/95681/121441/7277/79441/5116/54806/9814/91147/5048/1781/23354/80321/8766/22832/146057/8655/9738/79598/983/1639/55722/4957/10121/9702/5566/79959/132320/347240/84131/7846/7840/7283/3320/22919/27077/22994/11064/4867/79600/10540/84902/10733/1069/4751/117177/5577/80254/57545/26005/54930/5518/26123/10383/55835/54820/5347/23322/9662/80184/55142/23332/1453/22897/9793/4218/5108/261734/8481/57787/93323/10806/51259/55755/9657/1778 95 Measles_virus R-HSA-69618 Mitotic Spindle Checkpoint 103/2735 112/10654 1.490527998951223e-50 1.2762645991019847e-048 6.432805048105277e-49 220134/5905/55839/11130/79682/5903/10403/11065/54908/6249/55143/246184/55055/25936/5525/9735/80776/1783/1058/7321/991/401541/79019/5526/348235/80152/8697/9212/1063/8379/3619/79172/147841/348995/23421/79023/55920/57122/79980/64105/6232/332/1780/8881/23122/5528/5048/1781/5501/57405/8655/4085/23279/55166/51433/79902/3796/54821/5519/9183/81565/2491/1062/699/22919/1060/91687/119504/79003/5529/51143/51529/7324/83540/64682/29945/10393/11004/5527/51434/701/7514/9184/5518/25906/54820/5347/57551/84643/29882/6396/23332/25909/64946/9793/10726/81930/55746/140735/996/5515/1778/5516 103 Measles_virus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 85/2735 86/10654 1.5371366086172611e-49 1.1699317521142488e-47 5.896851551186685e-48 8454/5718/1017/5689/8945/26271/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/9212/5717/9491/6500/23198/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/8556/7324/5719/64682/29945/10393/4751/9232/5704/6233/51434/5716/701/51343/7311/9184/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 85 Measles_virus R-HSA-453276 Regulation of mitotic cell cycle 85/2735 86/10654 1.5371366086172611e-49 1.1699317521142488e-47 5.896851551186685e-48 8454/5718/1017/5689/8945/26271/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/9212/5717/9491/6500/23198/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/8556/7324/5719/64682/29945/10393/4751/9232/5704/6233/51434/5716/701/51343/7311/9184/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 85 Measles_virus R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 110/2735 125/10654 2.691379468491492e-49 1.940626248333339e-47 9.781412361941378e-48 56955/4240/3371/3270/351/9210/8720/7018/2153/4052/1511/5340/10618/54587/11167/7184/7857/56975/813/5179/401138/3486/8074/7425/51246/334/29106/6383/91851/3912/348/3827/3490/338/6696/64856/4924/51156/3484/335/5589/5611/2621/1435/102/3915/8614/5768/1471/336/1462/6694/265/4148/10232/462/197/11098/3053/3698/174/57104/721/10130/5265/2335/1758/3895/2200/258/5624/80341/7466/375056/1000/54757/11320/8404/255738/3913/5954/354/652/116519/2266/51280/10272/57719/7076/3479/147111/2243/1114/84141/213/2719/720/10117/3956/3569/10970/3488/8542/54972/5034/3487/1356/2519/4221/718 110 Measles_virus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 85/2735 88/10654 1.1096562198452514e-46 7.601145105939972e-45 3.831234106413078e-45 8454/115106/8945/22995/55559/11258/22981/8636/7531/10142/4659/11190/203068/54801/7532/84962/55125/1454/10382/95681/6500/121441/7277/79441/9133/5116/9814/5048/1781/23354/7316/80321/891/8655/9738/983/1639/6790/55722/4957/10121/9702/5566/79959/84131/23291/7846/7840/7283/3320/22919/22994/11064/10540/10733/79866/1069/4751/5577/6233/80254/7311/54930/5518/10133/10383/55835/54820/5347/9662/80184/55142/23332/1453/22897/9793/4218/5108/8481/93323/10806/55755/5500/7314/1778 85 Measles_virus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 79/2735 80/10654 5.7192617004188934e-46 3.731137395035183e-44 1.8806193862029042e-44 8454/5718/1017/5689/8945/26271/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/6500/23198/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/701/51343/7311/9184/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 79 Measles_virus R-HSA-913531 Interferon Signaling 146/2735 199/10654 8.332314521884689e-46 5.188759497719101e-44 2.615310203998256e-44 3135/3443/23165/3665/818/3460/5777/815/3837/3838/3441/5903/6737/51447/10379/402569/5335/55706/7175/115362/960/5770/9631/3455/7412/3107/10410/2316/817/2633/9021/85363/54739/9830/4600/23650/348995/9636/79023/2537/3383/57122/23636/11274/8638/3449/25820/1982/7706/2634/3444/10762/3662/23511/7316/3122/3394/53371/3663/8519/3664/567/103/4734/3434/3113/6772/8651/23279/4927/9688/3433/3659/3106/79902/23586/6041/3459/25939/1958/9883/4939/6059/3451/3717/23225/3448/1981/3440/5771/1973/3458/3454/816/11074/3661/3669/8086/10346/7324/3836/9246/5371/3439/51191/4599/6233/5580/684/3716/7311/81603/9972/3133/7318/3429/5610/10581/3134/5300/8021/3452/3127/4940/91543/6396/3437/129401/7334/3456/6773/4938/7297/5781/4261/3430/55746/3105/5696/3660/3446/8480/7314/3445/5595/8554 146 Measles_virus R-HSA-9006925 Intracellular signaling by second messengers 194/2735 305/10654 1.8570255124192243e-45 1.1061412834844946e-43 5.575326023556114e-44 5295/1912/1147/5718/2308/818/5689/5170/3725/23396/815/3643/3838/5684/8841/5290/5720/3667/5335/2309/5682/90865/23035/5291/5468/2065/5525/1822/23186/842/5700/3815/572/122706/5707/23239/5978/5526/9112/9219/817/10273/207/6045/5690/5594/4303/84335/5717/1027/8074/9491/7249/23198/930/5931/112/941/143471/114/5706/2064/57761/5705/6199/10197/108/192670/4615/113/5528/2100/7316/10213/5709/1950/5695/2263/111/107/4233/1026/55615/4734/10768/5714/6714/2099/1108/11060/9861/64223/5566/81847/10014/5715/5519/8503/5711/1958/5928/2932/2261/5701/5688/5159/5687/5685/3164/5683/5698/5708/10000/3084/5692/5686/5713/2534/23512/5728/5699/6009/5529/2444/5710/6615/816/3630/5702/3066/3065/7157/1107/23028/8975/942/5719/3654/7189/5371/208/10542/5577/5704/6233/5527/2885/79109/5580/2475/5716/7409/51135/8660/1385/57504/7311/3932/2931/5293/5518/5155/1386/1956/4254/118788/5296/5581/4343/117145/8726/196883/648/115/5694/23466/801/5781/57521/5693/5721/5696/23608/109/5691/5156/940/7314/5879/253260/5595/4193/5515/5516 194 Measles_virus R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 80/2735 82/10654 4.484389901474189e-45 2.457445666007855e-43 1.238635694891397e-43 114791/10844/115106/22995/55559/440145/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/653784/5048/1781/23354/728642/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/984/80097/10426/22994/11064/10540/10733/85378/1069/4751/5577/27175/80254/54930/5518/10383/55835/54820/5347/29922/9662/80184/55142/23332/1453/22897/27229/9793/5108/8481/93323/10806/55755/1778 80 Measles_virus R-HSA-380287 Centrosome maturation 80/2735 82/10654 4.484389901474189e-45 2.457445666007855e-43 1.238635694891397e-43 114791/10844/115106/22995/55559/440145/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/653784/5048/1781/23354/728642/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/984/80097/10426/22994/11064/10540/10733/85378/1069/4751/5577/27175/80254/54930/5518/10383/55835/54820/5347/29922/9662/80184/55142/23332/1453/22897/27229/9793/5108/8481/93323/10806/55755/1778 80 Measles_virus R-HSA-168898 Toll-like Receptor Cascades 123/2735 155/10654 5.070587385673531e-45 2.6718095070664376e-43 1.3466823178145085e-43 54106/8454/23643/1147/3665/23098/3725/11035/4064/8945/1326/10695/351/81793/4790/6885/11213/7184/7321/8737/10392/653509/8767/5336/3684/1849/29110/5594/6271/1785/4214/6500/330/51295/23118/6280/10333/841/7099/8517/4615/7098/7100/338/5528/7323/7316/7335/5970/7096/4792/5289/9261/59307/4793/6279/177/5641/8651/26052/3146/7322/5519/64127/5598/1432/329/23291/2244/929/114609/3656/10454/6288/3661/695/3654/7189/6285/1513/6233/51311/10010/948/1520/2266/51135/1385/81622/2353/7311/1759/5518/2243/1386/7187/8772/9641/6197/5599/353376/5600/7334/7097/3929/3551/6416/5781/5608/3689/9450/4791/671/51231/1508/51284/7314/5595/5515/148022/257397/1514/5516 123 Measles_virus R-HSA-5663202 Diseases of signal transduction 223/2735 377/10654 1.4335917575303164e-44 7.274150769690865e-43 3.6664179061983925e-43 5295/8454/1147/5718/2308/818/5689/5170/815/8805/7276/5684/4893/11052/6464/26127/8841/5290/5720/3667/5335/71/79718/1487/142678/2309/5682/5291/1499/2065/10018/5525/892/10142/842/55750/5700/3815/572/122706/5707/10956/5430/5526/23462/817/207/1452/5690/55534/5594/3280/9530/4303/84335/613/5717/1027/8074/9491/7249/6500/23198/409/930/84441/7414/941/10533/55109/10013/143471/23385/5706/2064/5705/23164/6199/10197/10046/9208/6776/5528/2100/84447/7316/10213/5709/673/9978/1950/9611/5695/8546/6774/2263/89780/4233/9759/9612/102/1026/55615/5714/6772/6714/2099/50846/4609/7415/9861/64223/10014/5715/22938/5519/8503/5711/399687/2932/2261/5701/867/5688/1387/5437/5159/5687/3717/4088/5685/2244/6907/3164/5683/5698/5708/10000/3320/3084/5692/5686/5713/324/2335/2534/2033/408/55294/5728/5699/6400/5529/1445/5710/11064/816/5702/3066/3065/5894/4087/942/5719/208/9794/5704/6233/5527/2885/79109/2475/5716/2266/7409/8660/1385/7048/7311/51009/8826/27248/3932/2931/5293/5518/5155/2243/7450/1956/11160/60/4254/118788/5296/7040/3845/6777/5694/3265/3516/369/801/9715/5781/5693/5721/5696/7750/11140/5691/5245/7529/5156/940/7314/1523/5879/253260/5595/4193/5515/5516 223 Measles_virus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 75/2735 76/10654 1.3613921666038339e-43 6.66109738659733e-42 3.357418275534267e-42 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/4751/9232/5704/6233/51434/5716/701/7311/9184/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 75 Measles_virus R-HSA-1257604 PIP3 activates AKT signaling 173/2735 264/10654 3.4641290113983544e-43 1.636502326074395e-41 8.248524978139094e-42 5295/1912/1147/5718/2308/5689/5170/3725/23396/3643/5684/8841/5290/5720/3667/2309/5682/90865/23035/5291/5468/2065/5525/1822/23186/842/5700/3815/572/122706/5707/23239/5978/5526/9112/9219/10273/207/6045/5690/5594/4303/84335/5717/1027/8074/9491/7249/23198/930/5931/941/143471/5706/2064/57761/5705/6199/10197/192670/4615/5528/2100/7316/10213/5709/1950/5695/2263/4233/1026/55615/4734/5714/6714/2099/1108/11060/9861/64223/81847/10014/5715/5519/8503/5711/1958/5928/2932/2261/5701/5688/5159/5687/5685/3164/5683/5698/5708/10000/3084/5692/5686/5713/2534/23512/5728/5699/6009/5529/2444/5710/6615/3630/5702/3066/3065/7157/1107/23028/8975/942/5719/3654/7189/5371/208/10542/5704/6233/5527/2885/79109/2475/5716/7409/51135/8660/1385/57504/7311/3932/2931/5293/5518/5155/1386/1956/4254/118788/5296/4343/117145/8726/648/5694/23466/5781/57521/5693/5721/5696/23608/5691/5156/940/7314/5879/253260/5595/4193/5515/5516 173 Measles_virus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 74/2735 75/10654 5.341421726862172e-43 2.439249255267058e-41 1.229464088709328e-41 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/4751/9232/5704/6233/51434/5716/701/7311/9184/25906/29882/5694/5693/5721/5696/5691/7314/996 74 Measles_virus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72/2735 73/10654 8.211191749639062e-42 3.6288169990340373e-40 1.829046447457801e-40 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/890/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/4751/5704/6233/51434/5716/701/7311/9184/25906/29882/5694/5693/5721/5696/5691/7314/996 72 Measles_virus R-HSA-141424 Amplification of signal from the kinetochores 87/2735 96/10654 1.4928417053125686e-41 6.1975549584188455e-40 3.123777220685949e-40 220134/5905/55839/11130/79682/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/401541/79019/5526/348235/80152/9212/1063/8379/3619/79172/147841/348995/23421/79023/55920/57122/79980/64105/6232/332/1780/23122/5528/5048/1781/5501/57405/8655/4085/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/22919/1060/91687/79003/5529/51143/83540/11004/5527/701/7514/9184/5518/54820/5347/57551/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/5515/1778/5516 87 Measles_virus R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 87/2735 96/10654 1.4928417053125686e-41 6.1975549584188455e-40 3.123777220685949e-40 220134/5905/55839/11130/79682/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/401541/79019/5526/348235/80152/9212/1063/8379/3619/79172/147841/348995/23421/79023/55920/57122/79980/64105/6232/332/1780/23122/5528/5048/1781/5501/57405/8655/4085/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/22919/1060/91687/79003/5529/51143/83540/11004/5527/701/7514/9184/5518/54820/5347/57551/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/5515/1778/5516 87 Measles_virus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 71/2735 72/10654 3.2171979485487066e-41 1.2593031970033509e-39 6.34731384736226e-40 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/9212/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/9232/5704/6233/51434/5716/51343/7311/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 71 Measles_virus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 71/2735 72/10654 3.2171979485487066e-41 1.2593031970033509e-39 6.34731384736226e-40 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/890/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/701/7311/9184/25906/29882/5694/5693/5721/5696/5691/7314/996 71 Measles_virus R-HSA-2500257 Resolution of Sister Chromatid Cohesion 103/2735 126/10654 4.71044968194127e-40 1.7925877956276502e-38 9.035248512729454e-39 220134/5905/55839/11130/79682/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/401541/79019/5526/348235/80152/10382/9212/1063/8379/3619/79172/10274/147841/23244/7277/348995/23421/79023/55920/9133/10381/57122/79980/64105/10735/6232/332/23047/1780/5885/23122/5528/5048/1781/891/5501/57405/8655/4085/983/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/7846/22919/1060/91687/79003/8243/9126/5529/51143/83540/11004/5527/701/7514/9184/5518/10383/54820/5347/113130/57551/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/5515/1778/5516 103 Measles_virus R-HSA-9020702 Interleukin-1 signaling 90/2735 103/10654 6.213169846064319e-40 2.3005520781373289e-38 1.1595560224802826e-38 8454/3557/1147/5718/5689/8945/1326/5684/351/5720/4790/6885/5682/11213/5700/122706/5707/10392/8767/5690/3553/8878/54472/5717/9491/6500/23198/23118/143471/5706/5705/10197/8517/4615/7316/10213/5709/9978/5695/7335/5970/4792/4793/5714/177/3146/9861/5715/64127/5711/3552/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/3656/5699/5710/10454/6288/5702/5719/3654/7189/6285/5704/6233/5716/51135/7311/7334/5694/3551/6416/5608/5693/5721/5696/5691/4791/3554/7314/257397 90 Measles_virus R-HSA-69242 S Phase 121/2735 161/10654 6.517201248146481e-40 2.3496225552528105e-38 1.1842892018792498e-38 8454/5718/1017/4172/6118/5689/2237/5684/994/5720/11065/8318/5682/246184/7027/5700/122706/7321/5707/207/8697/5690/5717/1027/9491/6500/23198/898/10274/5925/23244/4173/143471/5706/5705/10735/10197/4149/286826/23047/8881/5934/5885/7316/10213/5709/5422/9978/1869/4174/5753/993/5695/890/1026/5425/5714/5111/4171/4609/51433/9861/5715/6119/5711/5928/2932/5701/5688/5687/91750/6502/5685/5683/5698/5708/10000/5692/5686/990/5713/119504/8243/9126/5699/4175/5710/81620/5702/8900/51529/7324/5719/64682/29945/10393/208/5704/6233/51434/5716/55957/51343/23595/7311/25906/113130/157570/6117/29882/5694/7465/1163/5693/5721/5696/132660/5691/4176/7314/996 121 Measles_virus R-HSA-8854518 AURKA Activation by TPX2 71/2735 73/10654 8.82779944108101e-40 3.1010474959694836e-38 1.563032775532832e-38 115106/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/22974/10382/3161/95681/121441/7277/79441/5116/9814/5048/1781/23354/80321/8655/9738/983/1639/6790/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/22994/11064/10540/10733/1069/4751/5577/80254/54930/5518/10383/55835/54820/5347/9662/80184/55142/23332/1453/22897/9793/5108/8481/93323/10806/55755/1778 71 Measles_virus R-HSA-69052 Switching of origins to a post-replicative state 82/2735 90/10654 1.1935210465424054e-39 4.0878095844077385e-38 2.06039422771531e-38 8454/5718/1017/4172/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/5717/9491/6500/23198/898/4173/143471/5706/5705/10197/8881/7316/10213/5709/9978/4174/5695/890/5714/4171/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/990/5713/119504/5699/4175/5710/81620/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/23595/7311/25906/29882/5694/5693/5721/5696/5691/4176/7314/996 82 Measles_virus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 70/2735 72/10654 3.4097079951088927e-039 1.1393414520241909e-37 5.742666097025504e-38 5718/1017/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/5717/9491/23198/898/143471/5706/5705/10197/8881/7316/10213/5709/5695/890/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/990/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 70 Measles_virus R-HSA-1236974 ER-Phagosome pathway 77/2735 83/10654 1.0270481555657431e-38 3.3501332693454e-37 1.6885804261933017e-37 23643/1147/3135/5718/5689/5684/5720/10952/5682/5700/3107/122706/5707/5690/6890/55176/5717/9491/23198/811/143471/5706/6892/5705/10333/10197/7099/8517/4615/23480/6891/7316/10213/5709/5695/29927/7096/567/5714/3106/9861/5715/5711/5701/5688/5687/5685/5683/929/5698/5708/5692/5686/5713/114609/5699/2923/5710/5702/695/5719/5704/6233/948/5716/7311/3133/3134/5694/7097/3551/3105/5693/5721/5696/5691/7314 77 Measles_virus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 66/2735 67/10654 2.949268960257303e-38 9.396508082680245e-37 4.736157742787737e-37 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/9232/5704/6233/51434/5716/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 66 Measles_virus R-HSA-380259 Loss of Nlp from mitotic centrosomes 68/2735 70/10654 5.076582381554657e-38 1.5455373028288622e-36 7.790030508303754e-37 115106/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/5048/1781/23354/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/22994/11064/10540/10733/1069/4751/5577/80254/54930/5518/10383/55835/54820/5347/9662/80184/55142/23332/1453/22897/9793/5108/8481/93323/10806/55755/1778 68 Measles_virus R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 68/2735 70/10654 5.076582381554657e-38 1.5455373028288622e-36 7.790030508303754e-37 115106/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/5048/1781/23354/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/22994/11064/10540/10733/1069/4751/5577/80254/54930/5518/10383/55835/54820/5347/9662/80184/55142/23332/1453/22897/9793/5108/8481/93323/10806/55755/1778 68 Measles_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 70/2735 73/10654 6.23713625184618e-38 1.8575818837020146e-36 9.362840689270238e-37 8454/57154/5718/5689/7291/5684/5720/5682/5700/122706/5707/10273/5690/5717/9491/6500/23198/143471/5706/5705/10197/7316/10213/5709/9978/865/5695/11059/579/5714/6772/2099/9861/5715/5711/2932/5701/5688/5687/6502/2908/5685/5683/5698/5708/5692/5686/5713/2101/1749/55294/5699/4488/5710/5702/5719/5704/6233/5716/7311/860/1750/5694/133522/5693/5721/5696/5691/10891/7314 70 Measles_virus R-HSA-2262752 Cellular responses to stress 251/2735 479/10654 1.6713242933341685e-37 4.871732514612364e-36 2.4555178867350828e-36 1912/5718/1017/23165/818/3303/7014/6118/5689/3725/4688/6782/815/5684/5903/5720/11065/573/2876/4790/55706/7175/11258/5682/9631/9448/246184/112399/7531/7290/7027/1915/1783/526/5700/122706/116835/7321/5707/84962/817/2878/6045/7422/8697/5690/10382/2936/5594/9530/3308/84335/23677/5717/1027/9491/23198/898/10049/5931/7295/10294/5925/55860/7277/348995/10013/143471/545/79023/5706/472/10381/57122/5705/23636/10197/3337/192670/3576/3313/10808/1780/10762/3490/8881/7001/23511/7323/1781/7316/10213/5709/9978/1869/5695/890/10935/3305/53371/8655/6774/5970/1026/1639/9261/9532/54205/832/6667/5714/2289/9588/23279/4927/9688/10121/7415/6647/51433/9861/79902/64223/1031/7322/5715/2882/6119/5711/5598/9883/3552/5928/1432/2932/5701/5688/1387/5687/7846/259217/23225/3310/529/2908/5685/5683/3309/5698/5708/3320/5692/5686/5713/2877/2033/23512/119504/7266/5699/6009/5710/6767/51143/3301/816/25994/7428/5702/10540/493869/9531/7157/8453/8900/51529/50507/8086/23135/7324/10963/5719/64682/29945/10393/22824/10542/5704/6233/2056/51434/3326/2475/5716/3306/27000/2353/51343/7311/9972/538/25906/57634/10383/23411/8021/9529/4343/8726/6117/6197/29882/5599/6396/648/129401/5600/54583/5694/3304/3312/23466/4217/528/3456/6416/1536/5608/96459/3569/3297/57521/55746/5693/5721/55466/257202/140735/5696/5691/5034/8480/2880/7296/7314/996/51182/5595/2950/4193/1778 251 Measles_virus R-HSA-909733 Interferon alpha/beta signaling 67/2735 69/10654 1.9568218926539003e-37 5.585095818616341e-36 2.815077108730172e-36 3135/3443/3665/5777/3441/51447/10379/5770/3455/3107/10410/9021/54739/4600/9636/2537/11274/8638/3449/2634/3444/3662/3394/3663/8519/3664/103/3434/6772/8651/3433/3659/3106/6041/25939/1958/4939/6059/3451/3448/3440/3454/3661/3669/3439/4599/684/3716/3133/3429/10581/3134/3452/4940/91543/3437/3456/6773/4938/7297/5781/3430/3105/5696/3660/3446/3445 67 Measles_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 86/2735 101/10654 2.4720982354862823e-36 6.911784862482054e-35 3.483773238408166e-35 8454/1147/5718/5689/5170/8945/5684/4773/5720/4790/6885/5682/4772/5700/122706/7321/5707/5336/5690/3553/9039/5717/9491/6500/23198/23118/29108/143471/5706/5705/841/10197/8517/7316/10213/5709/5695/64581/9020/7335/5970/4792/6850/10768/8915/5714/6714/9861/7322/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/10454/5702/9040/5719/7189/5704/6233/5580/5716/7311/7334/5694/3551/801/5693/5721/5696/997/5691/4791/7314/257397 86 Measles_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 101/2735 129/10654 3.399281010305653e-36 9.314029968237489e-35 4.6945859847589645e-35 8454/23643/1147/3665/23098/3725/11035/4064/8945/1326/351/4790/6885/11213/7321/8737/10392/653509/8767/5336/3684/1849/29110/5594/1785/4214/6500/330/51295/23118/10333/841/7099/8517/4615/5528/7323/7316/7335/5970/7096/4792/9261/59307/4793/177/8651/26052/3146/7322/5519/64127/5598/1432/329/23291/929/114609/3656/10454/6288/3661/695/3654/7189/6285/6233/10010/948/51135/1385/2353/7311/1759/5518/1386/7187/8772/9641/6197/5599/353376/5600/7334/7097/3929/3551/6416/5781/5608/3689/9450/4791/671/51231/7314/5595/5515/148022/257397/5516 101 Measles_virus R-HSA-69206 G1/S Transition 102/2735 131/10654 3.681774218335669e-36 9.890256233568365e-35 4.985023503050977e-35 8454/5718/1017/4172/6118/5689/26271/5684/5720/8318/5682/7027/5700/5707/8317/207/5690/5717/1027/9491/6500/898/5925/4173/5706/5705/10197/4149/286826/5934/7316/10213/5709/5422/1869/4174/891/5753/993/5695/890/1876/983/1026/5933/5714/5111/4171/4609/9861/5715/5519/6119/5711/5928/5701/5688/5687/91750/6502/5685/5683/5698/5708/10000/5692/5686/990/5713/5699/4175/5710/81620/5702/3065/8900/5719/208/5704/6233/7298/55388/5716/55957/23595/7311/5518/6117/5694/7465/1163/5693/5721/5696/7083/132660/5691/4176/7314/5515/6241/5516 102 Measles_virus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 62/2735 63/10654 6.848616235908421e-36 1.8043469698451031e-34 9.094518726226566e-35 5718/5689/5684/5720/11065/5682/246184/5700/7321/5707/8697/5690/5717/9491/5706/5705/10197/8881/7316/10213/5709/5695/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 62 Measles_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 103/2735 134/10654 1.2798281447973414e-35 3.308235015796901e-34 1.6674622899445004e-34 5295/8454/1147/5718/5689/5170/3725/8945/5684/4893/6464/4773/5290/5720/5335/4790/6885/5682/5291/4772/5700/122706/7321/5707/5336/5690/5594/5717/4214/9491/6500/23198/23118/143471/5706/5705/10197/8517/7316/10213/5709/5695/7335/5970/4792/6850/10768/8915/5714/9861/7322/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/2534/5699/5710/10454/5702/695/5719/7189/5704/6233/2885/7410/7006/5716/7409/3702/2353/7311/5296/3845/5599/7334/5694/3265/3551/5058/801/6416/5062/5693/5721/5696/997/5691/7314/5879/5595/257397 103 Measles_virus R-HSA-8953897 Cellular responses to external stimuli 252/2735 493/10654 2.7171480892557155e-35 6.893505337556167e-34 3.4745597398669574e-34 1912/5718/1017/23165/818/3303/7014/6118/5689/3725/4688/6782/815/5684/5903/5720/11065/573/2876/4790/55706/7175/11258/5682/9631/9448/246184/112399/7531/7290/7027/1915/1783/526/5700/122706/116835/7321/5707/84962/817/2878/6045/7422/8697/5690/10382/2936/5594/9530/3308/84335/23677/5717/1027/9491/23198/898/10049/5931/7295/10294/5925/55860/7277/348995/10013/143471/545/79023/5706/472/10381/57122/5705/23636/10197/3337/192670/3576/3313/10808/1780/10762/3490/8881/7001/23511/7323/1781/7316/10213/5709/9978/1869/5695/890/10935/3305/53371/8655/6774/5970/1026/1639/9261/9532/54205/832/6667/5714/2289/9588/23279/4927/9688/10121/7415/6647/51433/9861/79902/64223/1031/7322/5715/2882/6119/5711/5598/9883/3552/5928/1432/2932/5701/5688/1387/5687/7846/259217/23225/3310/529/2908/5685/5683/3309/5698/5708/3320/5692/5686/5713/2877/2033/23512/119504/7266/5699/6009/5710/6767/51143/3301/816/25994/7428/5702/10540/493869/9531/7157/8453/8900/51529/50507/8086/23135/7324/10963/5719/64682/29945/10393/22824/10542/5704/6233/2056/51434/3326/2475/5716/3306/27000/2353/51343/7311/9972/538/25906/57634/10383/23411/8021/9529/4343/8726/6117/6197/29882/5599/6396/648/129401/5600/54583/5694/3304/3312/23466/4217/528/3456/6416/1536/5608/96459/3569/3297/57521/55746/5693/5721/55466/257202/140735/5696/5691/5034/8480/2880/7296/7314/996/51182/6620/5595/2950/4193/1778 252 Measles_virus R-HSA-1236975 Antigen processing-Cross presentation 84/2735 99/10654 2.8413333157623367e-35 7.077502986535275e-34 3.5673007753877372e-34 23643/1147/3135/5718/5689/4688/5684/5720/10952/5682/5700/3107/122706/5707/5690/6890/55176/5717/9491/23198/811/143471/5706/6892/5705/10333/10197/7099/8517/4615/23480/6891/7316/10213/5709/5695/29927/7096/567/5714/3106/9861/5715/5711/5701/5688/5687/5685/5683/929/5698/5708/5692/5686/5713/114609/5699/2923/5710/5702/695/5719/5704/6233/948/1520/4012/5716/3685/7311/3133/3134/5694/7097/3551/1536/3105/5693/5721/5696/5691/7314/4360/1514 84 Measles_virus R-HSA-453279 Mitotic G1-G1/S phases 110/2735 149/10654 3.837839373961116e-35 9.388999897012016e-34 4.732373363380624e-34 8454/5718/1017/4172/6118/5689/25/26271/5684/5720/4605/8318/5682/7027/5700/5707/8317/207/5690/5717/1027/9491/6500/7153/898/5925/4173/5706/5705/10197/4149/286826/5934/7316/10213/5709/5422/1869/4174/891/5753/993/5695/890/1876/983/1026/5933/5714/5111/6714/4171/4609/9861/1031/5715/5519/6119/5711/5928/5701/5688/5687/91750/4067/3717/6502/5685/5683/5698/5708/10000/5692/5686/990/5713/5699/4175/5710/81620/5702/3065/8900/5719/208/5704/6233/7298/55388/5716/55957/23595/7311/5518/6117/5694/7465/1163/1859/5693/5721/5696/7083/132660/5691/4176/7314/5515/6241/5516 110 Measles_virus R-HSA-446652 Interleukin-1 family signaling 105/2735 140/10654 1.261697274367785e-34 3.032500466462922e-33 1.528482755282118e-33 8454/3557/1147/5718/834/5689/5777/8945/1326/5684/351/5720/4790/6885/5682/90865/1511/11213/5700/122706/5707/10392/8767/29110/5690/3553/8878/54472/5717/9491/6500/23198/23118/143471/5706/5705/10197/8517/4615/7316/3565/10213/5709/9978/5695/6774/7335/5970/4792/59307/4793/5714/3606/177/3146/9861/5715/64127/5711/3552/5701/5688/5687/23291/4088/5685/5683/5698/5708/5692/5686/5713/3656/5699/5771/5710/10454/6288/5702/5719/3654/7189/6285/5704/6233/5716/51135/7311/5599/5784/7334/5694/3551/6416/5781/5608/5693/5721/5696/5691/4791/3554/7314/3596/257397 105 Measles_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 71/2735 78/10654 2.130557790450298e-34 5.032524436063635e-33 2.5365624510624233e-33 1147/3443/3665/3441/351/7186/4790/80143/7321/8737/9140/29110/57506/79132/4214/9636/54476/3449/841/7706/8517/3444/84166/7323/9474/7316/5970/4792/4793/177/3093/3146/23586/7322/7128/1387/3451/843/3448/2033/64135/3440/6288/54941/83737/3661/9246/7189/3439/6285/51191/6233/10010/7311/55593/84282/7318/79671/5094/7187/8772/5300/3452/9641/1540/3551/3456/4791/3446/7314/3445 71 Measles_virus R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 80/2735 94/10654 7.6885441170566336e-34 1.7853060068419642e-32 8.99854583548466e-33 114791/10844/115106/4926/22995/55559/440145/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/10381/5116/9814/653784/5048/1781/23354/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/80097/10426/22994/11064/10540/10733/85378/1069/4751/5577/27175/80254/54930/5518/10383/55835/54820/5347/29922/9662/80184/55142/23332/1453/22897/27229/9793/5108/8481/93323/10806/55755/1778 80 Measles_virus R-HSA-5663220 RHO GTPases Activate Formins 104/2735 140/10654 1.108015819042741e-33 2.529969453480925e-32 1.275190135600067e-32 220134/5905/55839/11130/79682/5903/10403/54908/71/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/1856/401541/79019/5526/348235/80152/10382/9212/1063/6722/8379/3619/79172/147841/7277/348995/23421/79023/55920/10381/57122/79980/64105/6232/332/1780/23122/5528/3688/5048/1781/5501/57405/8655/4085/5216/6714/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/7846/752/22919/1060/91687/79003/5529/51143/998/83540/11004/5527/701/1857/7514/9184/5518/10383/54820/5347/387/57551/60/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/5879/5515/1778/5516 104 Measles_virus R-HSA-3371556 Cellular response to heat stress 77/2735 89/10654 1.1666527497645189e-33 2.620187323241625e-32 1.3206629919681178e-32 23165/818/3303/6118/6782/815/5903/573/55706/7175/9631/7531/1915/116835/817/5594/9530/3308/84335/10049/348995/10013/545/79023/472/57122/23636/3337/3313/10808/10762/23511/3305/53371/9261/9532/23279/4927/9688/7415/79902/64223/6119/9883/2932/1387/259217/23225/3310/3309/3320/2033/7266/6767/816/9531/8086/22824/3326/2475/3306/27000/9972/23411/8021/9529/6117/6396/129401/3304/3312/3297/57521/55746/8480/51182/5595 77 Measles_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 74/2735 85/10654 8.763884793232523e-33 1.9365358333433157e-31 9.760795287539108e-32 8454/5718/1017/5689/5684/994/5720/5682/7027/5700/5707/207/5690/5717/1027/9491/6500/898/5925/5706/5705/10197/4149/286826/5934/7316/10213/5709/1869/5753/993/5695/890/1026/5714/4609/9861/5715/5711/5928/5701/5688/5687/91750/6502/5685/5683/5698/5708/10000/5692/5686/5713/5699/5710/5702/8900/5719/208/5704/6233/5716/55957/51343/7311/5694/7465/1163/5693/5721/5696/132660/5691/7314 74 Measles_virus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 58/2735 60/10654 3.5558575325716474e-32 7.732579078766916e-31 3.8974812721253144e-31 8454/1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/9039/5717/9491/6500/23198/143471/5706/5705/10197/7316/10213/5709/5695/9020/5970/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/4791/7314 58 Measles_virus R-HSA-69202 Cyclin E associated events during G1/S transition 72/2735 83/10654 1.0466291749272053e-31 2.240440577578549e-30 1.1292577940004057e-30 8454/5718/1017/5689/5684/5720/5682/7027/5700/5707/207/5690/5717/1027/9491/6500/898/5925/5706/5705/10197/4149/286826/5934/7316/10213/5709/1869/5753/993/5695/890/1026/5714/4609/9861/5715/5711/5928/5701/5688/5687/91750/6502/5685/5683/5698/5708/10000/5692/5686/5713/5699/5710/5702/8900/5719/208/5704/6233/5716/55957/7311/5694/7465/1163/5693/5721/5696/132660/5691/7314 72 Measles_virus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 57/2735 59/10654 1.3601886918305013e-31 2.8668592427812105e-30 1.444993978689569e-30 8454/1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/9039/5717/9491/6500/23198/143471/5706/5705/10197/7316/10213/5709/5695/9020/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/4791/7314 57 Measles_virus R-HSA-162909 Host Interactions of HIV factors 96/2735 129/10654 2.786249839533871e-31 5.783579212365762e-30 2.9151194493368724e-30 5718/23165/5689/5905/8945/1173/3837/5684/5903/8065/5720/55706/7175/5682/9631/5700/122706/5707/5690/5717/4869/9491/6500/23198/348995/143471/79023/5706/57122/5705/23636/10197/10762/23511/7316/10213/5709/9978/5695/53371/292/567/3055/5714/23279/4927/9688/9861/79902/5715/5711/11168/9883/5701/5688/5687/23225/5685/5683/5698/5708/5692/5686/5713/2534/5699/5710/5702/8086/5478/5719/3836/5704/6233/5716/7514/163/1025/7311/9972/3932/8021/6396/129401/5694/5062/55746/5693/5721/5696/8907/5691/8480/940/7314/5879 96 Measles_virus R-HSA-1169091 Activation of NF-kappaB in B cells 62/2735 67/10654 3.3509956111168967e-31 6.852035801836043e-30 3.4536576918973825e-30 8454/1147/5718/5689/8945/5684/5720/4790/6885/5966/5682/5700/122706/5707/5690/5717/9491/6500/23198/143471/5706/5705/10197/8517/7316/10213/5709/5695/5970/4792/4793/8915/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/3551/5693/5721/5696/5691/7314 62 Measles_virus R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 54/2735 55/10654 3.5983749997311922e-31 7.159273907079609e-30 3.6085160837834975e-30 8454/5718/5689/8945/26271/5684/5720/5682/5700/122706/5707/991/5690/5717/9491/6500/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/51343/7311/5694/5693/5721/5696/5691/7314 54 Measles_virus R-HSA-2871837 FCERI mediated NF-kB activation 71/2735 82/10654 3.6057656904269557e-31 7.159273907079609e-30 3.6085160837834975e-30 8454/1147/5718/5689/5170/8945/5684/5720/4790/6885/5682/5700/122706/7321/5707/5690/5717/9491/6500/23198/23118/143471/5706/5705/10197/8517/7316/10213/5709/5695/7335/5970/4792/8915/5714/9861/7322/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/10454/5702/5719/7189/5704/6233/5716/7311/7334/5694/3551/5693/5721/5696/997/5691/7314/257397 71 Measles_virus R-HSA-5688426 Deubiquitination 169/2735 297/10654 5.348557170550262e-31 1.0467890462362657e-29 5.276170682527777e-30 9960/5718/23358/5689/10600/23032/5684/8295/5720/114785/3607/221937/7186/645836/6885/5682/90865/5700/122706/7321/5707/991/51377/8737/10392/8767/8237/171023/4738/5690/55611/2625/9817/57506/4303/10445/100287364/91833/5717/9491/57646/23198/63967/409/6478/1080/330/9101/143471/5706/100287513/5705/57695/11274/4287/55031/27005/10197/7706/8517/64750/580/7416/29086/7316/10213/5709/993/5695/890/7417/4792/9738/9986/983/8314/55252/5714/8678/2099/4609/7415/392188/9861/23586/81847/5715/100287144/64426/100287441/64127/7128/5711/3416/5701/5688/329/5687/6502/7347/9099/4088/5685/5683/5698/5708/9146/5692/5686/5713/324/2033/408/55777/221656/64135/5728/5699/5710/10454/8473/100287327/5702/7157/8900/9929/9958/8313/8975/4087/10868/63891/5719/7189/57599/5704/6233/377630/5716/672/100287478/7048/9804/7311/55593/84282/79184/114548/7187/387/60/7040/728386/7345/3054/1540/5694/100287404/5693/154/5721/100287178/5696/5691/100287205/7314/4193/100287238/7528 169 Measles_virus R-HSA-5357801 Programmed Cell Death 120/2735 181/10654 6.303522607362107e-31 1.2163135171952235e-29 6.130631327545651e-30 23643/5718/1828/5689/2934/11035/3837/596/5684/5720/7186/2339/5682/1499/4976/10018/7531/5747/7027/842/5700/572/122706/5707/8737/7532/207/10971/5690/5594/10059/5717/9491/23198/63967/355/330/7533/2810/143471/5706/5705/841/10197/7099/7534/9500/7316/10213/5709/1869/5695/8655/6774/54205/5339/4836/5714/115209/3146/9861/5715/5711/5701/5688/10134/329/5687/22900/999/598/836/5685/5683/929/5698/5708/10000/5692/5686/5713/324/5699/4137/5710/5702/7157/8626/5719/3836/197259/208/5704/6233/5580/6709/5716/7311/7161/840/8772/5599/353376/8717/7159/7431/5694/26060/637/8743/5062/5693/5721/140735/5696/5691/7529/7314/5595/148022 120 Measles_virus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 53/2735 54/10654 1.396480230959705e-30 2.6571915505761054e-29 1.3393143735519977e-29 8454/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/6500/23198/143471/5706/5705/10197/7316/10213/5709/9978/5695/6790/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/23194/5694/5693/5721/5696/5691/7314 53 Measles_virus R-HSA-68949 Orc1 removal from chromatin 64/2735 71/10654 1.6599751660092887e-30 3.1152958594968844e-29 1.5702144324471422e-29 8454/5718/1017/4172/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/6500/23198/4173/143471/5706/5705/10197/7316/10213/5709/9978/4174/5695/890/5714/4171/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/990/5713/5699/4175/5710/81620/5702/8900/5719/5704/6233/5716/23595/7311/5694/5693/5721/5696/5691/4176/7314 64 Measles_virus R-HSA-69239 Synthesis of DNA 90/2735 119/10654 2.5826909335787473e-30 4.7315051835096984e-29 2.3848385711735398e-29 8454/5718/1017/4172/6118/5689/2237/5684/5720/11065/8318/5682/246184/5700/122706/7321/5707/8697/5690/5717/9491/6500/23198/898/4173/143471/5706/5705/10197/8881/7316/10213/5709/5422/9978/4174/5695/890/5425/5714/5111/4171/51433/9861/5715/6119/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/990/5713/119504/5699/4175/5710/81620/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/23595/7311/25906/6117/29882/5694/5693/5721/5696/5691/4176/7314/996 90 Measles_virus R-HSA-8878166 Transcriptional regulation by RUNX2 91/2735 121/10654 2.5902400639651635e-30 4.7315051835096984e-29 2.3848385711735398e-29 8454/57154/5718/5689/7291/25/5684/8841/5720/5682/5700/122706/5707/23462/10273/207/5690/5594/3280/5717/9491/6500/23198/5925/10013/143471/3958/5706/5705/10197/7316/10213/5709/9978/891/865/5695/11059/9759/983/1026/10413/579/5714/6772/6714/2099/9861/5715/5711/2932/5701/5688/5687/6502/2908/5685/5683/5698/5708/10000/5692/5686/5713/2101/1749/55294/5699/4488/5710/5702/23314/861/5719/208/5704/6233/7525/5716/7311/860/1750/5694/133522/5693/5721/5696/5691/10891/7314/5595 91 Measles_virus R-HSA-202424 Downstream TCR signaling 79/2735 98/10654 3.653060064771814e-30 6.585121432549191e-29 3.3191238261638643e-29 5295/8454/1147/5718/5689/5170/8945/5684/3635/5290/5720/4790/6885/5682/5291/5700/122706/7321/5707/8767/5690/5717/9491/6500/23198/23118/143471/5706/5705/10197/8517/7316/10213/5709/3122/5695/7335/5970/4792/8915/5714/3113/9861/7322/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5728/5699/5710/5702/5719/7189/5704/6233/5716/7311/3932/5296/3127/7334/5694/3551/5693/5721/5696/997/5691/7314 79 Measles_virus R-HSA-5621481 C-type lectin receptors (CLRs) 101/2735 142/10654 4.154368364211667e-30 7.391538518142838e-29 3.7255852999628893e-29 8454/1147/5718/5689/5170/8945/5684/4893/4773/5720/4790/6885/5682/4772/5700/122706/7321/5707/5336/5690/3553/9039/5717/9491/6500/23198/23118/29108/143471/5706/5705/841/10197/8517/7316/10213/5709/5695/64581/9020/7335/5970/4792/6850/10768/8915/5714/6714/9861/5566/7322/5715/93978/5711/170482/5701/5688/1387/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/2534/2033/5699/5710/10454/5702/9040/5894/5719/7189/5704/6233/5580/30835/5716/7311/3845/7334/5694/3265/3551/5058/801/5062/5693/5721/5696/997/5691/26253/4791/7314/257397 101 Measles_virus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 54/2735 56/10654 7.573497715457047e-30 1.3133787177438168e-28 6.619872753284241e-29 5718/3303/5689/5684/5720/5682/5700/122706/5707/5690/3184/5717/9491/3315/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/1981/5699/5710/5702/5719/5704/6233/5716/7311/5694/3304/3312/5693/5721/5696/5691/7314 54 Measles_virus R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 54/2735 56/10654 7.573497715457047e-30 1.3133787177438168e-28 6.619872753284241e-29 5718/5689/5684/5720/5682/5700/122706/5707/10956/5690/5717/9491/23198/143471/5706/5705/10197/84447/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/6400/5710/5702/5719/5704/6233/5716/7311/51009/27248/5694/5693/5721/5696/5691/7314 54 Measles_virus R-HSA-109581 Apoptosis 117/2735 178/10654 1.1742035233232607e-29 2.010823533691084e-28 1.0135230411842882e-28 23643/5718/1828/5689/2934/3837/596/5684/5720/7186/2339/5682/1499/4976/10018/7531/5747/7027/842/5700/572/122706/5707/8737/7532/207/10971/5690/5594/10059/5717/9491/23198/63967/355/7533/2810/143471/5706/5705/841/10197/7099/7534/9500/7316/10213/5709/1869/5695/8655/6774/54205/5339/4836/5714/115209/3146/9861/5715/5711/5701/5688/10134/329/5687/22900/999/598/836/5685/5683/929/5698/5708/10000/5692/5686/5713/324/5699/4137/5710/5702/7157/8626/5719/3836/208/5704/6233/5580/6709/5716/7311/7161/840/8772/5599/353376/8717/7159/7431/5694/26060/637/8743/5062/5693/5721/140735/5696/5691/7529/7314/5595/148022 117 Measles_virus R-HSA-69306 DNA Replication 93/2735 127/10654 2.0349789237475288e-29 3.4087798434997236e-28 1.7181402822403522e-28 8454/5718/1017/4172/6118/5689/2237/5684/5720/11065/8318/5682/246184/5700/122706/7321/5707/8317/8697/5690/5717/9491/6500/23198/898/4173/143471/5706/5705/10197/8881/7316/10213/5709/5422/9978/1869/4174/5695/890/5425/5714/5111/4171/51433/9861/5715/6119/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/990/5713/119504/5699/4175/5710/81620/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/55388/5716/51343/23595/7311/25906/6117/29882/5694/5693/5721/5696/5691/4176/7314/996 93 Measles_virus R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 51/2735 52/10654 2.0993363167893285e-29 3.4087798434997236e-28 1.7181402822403522e-28 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Measles_virus R-HSA-69610 p53-Independent DNA Damage Response 51/2735 52/10654 2.0993363167893285e-29 3.4087798434997236e-28 1.7181402822403522e-28 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Measles_virus R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 51/2735 52/10654 2.0993363167893285e-29 3.4087798434997236e-28 1.7181402822403522e-28 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Measles_virus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 62/2735 69/10654 2.1149363992516535e-29 3.4087798434997236e-28 1.7181402822403522e-28 23165/3303/6118/6782/5903/573/55706/7175/9631/7531/116835/5594/9530/3308/10049/348995/545/79023/472/57122/23636/3337/3313/10808/10762/23511/3305/53371/9261/9532/23279/4927/9688/79902/6119/9883/2932/259217/23225/3310/3309/7266/6767/9531/8086/22824/3306/27000/9972/23411/8021/9529/6117/6396/129401/3304/3312/3297/55746/8480/51182/5595 62 Measles_virus R-HSA-500792 GPCR ligand binding 230/2735 468/10654 5.734107949772509e-29 9.134567315335276e-28 4.604130740576213e-28 2788/729230/151/57007/10316/10803/2913/4544/4543/10663/4889/1880/9283/727/351/7476/11251/7852/2692/7472/9294/54331/3352/8484/10161/50833/338398/5726/117579/283869/338442/3579/59345/4986/2492/23566/6351/2358/2916/64805/6752/259293/6374/1237/5539/259287/1903/2852/2550/84539/50836/1230/50832/5179/3354/6753/846/3358/2841/4886/2919/3577/2918/7484/51289/10681/5368/6754/27202/8862/51764/259294/2150/94235/259290/301/8811/2912/3576/56670/5196/6360/3827/150/1604/5173/56923/2832/2693/2357/4985/27199/2920/2826/55970/2921/2778/1236/5727/2853/6352/140/6751/6376/259295/54361/165140/27198/89780/5443/6348/9568/186/3627/53637/2792/54429/50846/2840/2831/3361/6346/152/6364/7253/5367/80834/10563/134/5540/4988/259292/1901/6370/58191/2793/5030/5697/6755/1524/5744/5733/256933/1129/7252/643/10850/51083/2785/3355/2783/624/3351/2796/2784/4852/2782/1233/6288/6372/6366/185/2786/50834/339403/2861/259285/728/50838/2914/183/10022/5473/4283/8843/719/2847/6363/6373/57121/4987/2917/2833/6347/1268/9290/11255/50831/9170/187/1132/2359/1814/10874/50839/83756/80835/6357/6750/259296/8698/259289/56477/5660/50835/1815/2587/1325/53829/1232/9934/50840/1902/259286/3350/129521/154/1234/50837/2791/1269/59340/1813/50865/4887/2790/718/2787/6387/623 230 Measles_virus R-HSA-69615 G1/S DNA Damage Checkpoints 61/2735 68/10654 7.528118389324816e-29 1.185462321077586e-27 5.975130869203967e-28 5718/1017/5689/5684/5720/5682/5700/122706/5707/5690/5717/1027/9491/23198/898/11200/143471/5706/472/5705/10197/7316/10213/5709/993/5695/890/1026/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/7157/8900/5719/5704/6233/5716/7311/5694/51230/5693/5721/5696/5691/7314/4193 61 Measles_virus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 56/2735 60/10654 8.664515659871381e-29 1.3489075515936128e-27 6.798950087171802e-28 8454/5718/1017/5689/5684/5720/5682/5700/5707/5690/5717/1027/9491/6500/898/5706/5705/10197/7316/10213/5709/5753/5695/890/1026/5714/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/5719/5704/6233/5716/7311/5694/1163/5693/5721/5696/5691/7314 56 Measles_virus R-HSA-9604323 Negative regulation of NOTCH4 signaling 52/2735 54/10654 1.0992907178300072e-28 1.6921666105922583e-27 8.52909179061484e-28 8454/5718/5689/5684/5720/5682/5700/5707/207/5690/5717/9491/6500/5706/5705/10197/10460/7534/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/55294/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 52 Measles_virus R-HSA-202403 TCR signaling 88/2735 119/10654 1.9991462957362507e-28 3.0431449168429593e-27 1.5338479181321407e-27 5295/8454/1147/5718/5689/5170/8945/5684/3635/5290/5720/5335/4790/6885/5682/5291/4690/5700/122706/7321/5707/8767/5690/5717/9491/6500/23198/23118/143471/5706/5705/5788/10197/8517/7316/10213/5709/3122/5695/7335/5970/4792/8915/5714/3113/9861/7322/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/7408/5728/5699/1445/5710/5702/5719/7189/5704/6233/5716/3702/26191/7311/3932/5296/3127/7334/5694/3551/5058/5062/5693/5721/5696/997/5691/7314 88 Measles_virus R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 49/2735 50/10654 3.147831815331403e-28 4.739043502202222e-27 2.388638138643609e-27 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5062/5693/5721/5696/5691/7314 49 Measles_virus R-HSA-5387390 Hh mutants abrogate ligand secretion 55/2735 59/10654 3.1984340171624666e-28 4.76288543860063e-27 2.400655280616222e-27 5718/5689/5684/5720/5682/5700/122706/5707/10956/5690/5717/9491/23198/143471/5706/5705/10197/84447/7316/10213/5709/5695/5714/50846/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/6400/5710/5702/5719/5704/6233/5716/7311/51009/27248/5694/5693/5721/5696/5691/7314 55 Measles_virus R-HSA-169911 Regulation of Apoptosis 51/2735 53/10654 4.182108749272242e-28 6.16074084570212e-27 3.1052216632966502e-27 5718/5689/5684/5720/5682/4976/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/115209/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5062/5693/5721/5696/5691/7314 51 Measles_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 69/2735 83/10654 4.55848711190058e-28 6.643752492876377e-27 3.348675862717559e-27 8454/1147/5718/5689/8945/5684/4893/4773/5720/4790/6885/5966/5682/4772/5700/122706/5707/5690/5717/9491/6500/23198/143471/5706/5705/10197/8517/7316/10213/5709/5695/5970/4792/4793/8915/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5478/5719/5704/6233/5716/7311/3845/5694/3265/3551/801/5693/5721/5696/5691/7314 69 Measles_virus R-HSA-5678895 Defective CFTR causes cystic fibrosis 56/2735 61/10654 7.945605391718529e-28 1.1458399354373037e-26 5.77542065037934e-27 5718/5689/5684/5720/5682/5700/122706/5707/10956/5690/5717/9491/23198/1080/143471/91319/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/6400/5710/5702/5719/5704/6233/5716/7311/51009/27248/11160/5694/5693/5721/5696/5691/7314 56 Measles_virus R-HSA-69563 p53-Dependent G1 DNA Damage Response 59/2735 66/10654 9.48289195151487e-28 1.3393362859356053e-26 6.750707672483727e-27 5718/1017/5689/5684/5720/5682/5700/122706/5707/5690/5717/1027/9491/23198/898/11200/143471/5706/472/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/8900/5719/5704/6233/5716/7311/5694/51230/5693/5721/5696/5691/7314/4193 59 Measles_virus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 59/2735 66/10654 9.48289195151487e-28 1.3393362859356053e-26 6.750707672483727e-27 5718/1017/5689/5684/5720/5682/5700/122706/5707/5690/5717/1027/9491/23198/898/11200/143471/5706/472/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/8900/5719/5704/6233/5716/7311/5694/51230/5693/5721/5696/5691/7314/4193 59 Measles_virus R-HSA-8941858 Regulation of RUNX3 expression and activity 52/2735 55/10654 1.5149960975852412e-27 2.1179027078487555e-26 1.0674945650009864e-26 57154/5718/5689/5684/5720/5682/5700/5707/5690/5717/9491/5706/5705/10197/64750/7316/10213/5709/865/5695/5714/6714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/2033/5699/5710/5702/5719/5704/6233/5716/7311/7040/5694/5693/5721/5696/5691/7314/4193 52 Measles_virus R-HSA-180534 Vpu mediated degradation of CD4 50/2735 52/10654 1.5894477615560907e-27 2.1769420821282171e-26 1.0972524055905572e-26 5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/6500/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Measles_virus R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/2735 52/10654 1.5894477615560907e-27 2.1769420821282171e-26 1.0972524055905572e-26 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/472/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Measles_virus R-HSA-166166 MyD88-independent TLR4 cascade 77/2735 99/10654 1.620788995453125e-27 2.1769420821282171e-26 1.0972524055905572e-26 8454/23643/1147/3665/23098/3725/11035/8945/1326/351/4790/6885/7321/8737/10392/8767/1849/29110/5594/6500/330/23118/841/7099/8517/5528/7323/7316/7335/5970/4792/9261/4793/177/3146/7322/5519/64127/5598/1432/329/23291/929/3656/10454/6288/3661/3654/7189/6285/6233/10010/1385/2353/7311/5518/1386/7187/8772/9641/6197/5599/353376/5600/7334/3551/6416/5781/5608/4791/51231/7314/5595/5515/148022/257397/5516 77 Measles_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 77/2735 99/10654 1.620788995453125e-27 2.1769420821282171e-26 1.0972524055905572e-26 8454/23643/1147/3665/23098/3725/11035/8945/1326/351/4790/6885/7321/8737/10392/8767/1849/29110/5594/6500/330/23118/841/7099/8517/5528/7323/7316/7335/5970/4792/9261/4793/177/3146/7322/5519/64127/5598/1432/329/23291/929/3656/10454/6288/3661/3654/7189/6285/6233/10010/1385/2353/7311/5518/1386/7187/8772/9641/6197/5599/353376/5600/7334/3551/6416/5781/5608/4791/51231/7314/5595/5515/148022/257397/5516 77 Measles_virus R-HSA-5610783 Degradation of GLI2 by the proteasome 55/2735 60/10654 2.8850240980091738e-27 3.800464436800546e-26 1.915562559002042e-26 8454/5718/5689/8945/5684/5720/5682/5700/122706/5707/1452/5690/5717/9491/6500/23198/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5566/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 55 Measles_virus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 55/2735 60/10654 2.8850240980091738e-27 3.800464436800546e-26 1.915562559002042e-26 8454/5718/5689/8945/5684/5720/5682/5700/122706/5707/1452/5690/5717/9491/6500/23198/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5566/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 55 Measles_virus R-HSA-69541 Stabilization of p53 53/2735 57/10654 4.338950528423405e-27 5.661297356133395e-26 2.853485259795242e-26 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/472/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/51230/5693/5721/5696/5691/7314/4193 53 Measles_virus R-HSA-8878159 Transcriptional regulation by RUNX3 75/2735 96/10654 4.660455358308079e-27 6.023418717813272e-26 3.036006668371499e-26 57154/5718/5689/8463/5684/5720/2309/5682/1499/10018/5700/5707/5690/55534/3280/5717/9491/84441/5706/5705/10197/10046/64750/6696/7316/10213/5709/865/5695/9759/1026/10413/5714/6714/4609/9861/5715/22938/5711/5701/5688/1387/5687/4088/5685/5683/5698/5708/5692/5686/5713/2033/7003/5699/5710/5702/7157/861/5719/9794/5704/6233/5716/7311/7040/3845/5694/3516/5693/5721/5696/5691/3676/7314/4193 75 Measles_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 83/2735 112/10654 5.4904806032476124e-27 7.029867688270307e-26 3.543290974648729e-26 5295/8454/1147/5718/5689/5777/8945/5684/4893/4773/5720/4790/6885/5966/5682/4690/4772/5700/122706/5707/5336/5690/5717/9491/6500/23198/930/143471/5706/5705/10197/8517/7316/10213/5709/5695/5970/4792/6850/10768/4793/8915/5714/9861/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/2534/5699/5710/5702/695/5478/5719/5704/6233/2885/5716/7409/7311/5293/118788/3845/5694/3265/3551/801/5693/5721/5696/5691/7314 83 Measles_virus R-HSA-6807070 PTEN Regulation 96/2735 140/10654 1.0730864352543322e-26 1.3612300150911436e-25 6.8610594690725325e-026 1912/5718/5689/3725/5684/8841/5720/5682/5468/1822/23186/5700/122706/5707/5978/9112/9219/10273/207/6045/5690/5594/5717/9491/23198/5931/143471/5706/5705/10197/192670/7316/10213/5709/5695/4734/5714/1108/11060/9861/64223/81847/10014/5715/5711/1958/5928/5701/5688/5687/5685/5683/5698/5708/10000/5692/5686/5713/23512/5728/5699/6009/2444/5710/6615/5702/3066/3065/7157/1107/23028/8975/5719/5371/208/10542/5704/6233/2475/5716/57504/7311/1386/4343/8726/648/5694/23466/57521/5693/5721/5696/23608/5691/7314/5595 96 Measles_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 67/2735 82/10654 2.0328370085498255e-26 2.55503367129657e-25 1.2878233487288125e-25 8454/5718/5689/8945/5684/5720/1487/5682/1499/5525/5700/122706/5707/5526/1452/5690/5717/9491/6500/23198/143471/5706/5705/10197/5528/7316/10213/5709/9978/5695/5714/9861/5715/5519/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/324/5699/5529/5710/5702/3065/5719/5704/6233/5527/5716/7311/5518/5694/5693/5721/5696/5691/7314/5515/5516 67 Measles_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 73/2735 94/10654 4.476951057313183e-26 5.5758390441082375e-25 2.810411381432964e-25 8454/1147/3665/23098/3725/11035/8945/1326/351/4790/6885/7321/8737/10392/8767/1849/29110/5594/6500/330/23118/841/8517/7098/5528/7323/7316/7335/5970/4792/9261/4793/177/3146/7322/5519/64127/5598/1432/329/23291/3656/10454/6288/3661/3654/7189/6285/6233/10010/1385/2353/7311/5518/1386/7187/8772/9641/6197/5599/5600/7334/3551/6416/5608/4791/51231/7314/5595/5515/148022/257397/5516 73 Measles_virus R-HSA-4641257 Degradation of AXIN 51/2735 55/10654 5.849507077099924e-26 7.219661887952158e-25 3.638953667688525e-25 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/64750/7316/10213/5709/5695/5714/9861/81847/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8313/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Measles_virus R-HSA-5358346 Hedgehog ligand biogenesis 57/2735 65/10654 7.23637603664477e-26 8.851638544824407e-25 4.461525075224595e-25 5718/5689/5684/5720/5682/5700/122706/5707/10956/5690/5717/9491/23198/143471/5706/5705/10197/84447/7316/10213/5709/5695/5714/50846/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/6400/5710/5702/5719/5704/6233/5716/7311/51009/27248/147111/5694/5693/5721/5696/5691/5034/7314 57 Measles_virus R-HSA-5610780 Degradation of GLI1 by the proteasome 54/2735 60/10654 7.860617303669602e-26 9.450586404493999e-25 4.763415045215568e-25 8454/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/6500/23198/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5566/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/83737/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 54 Measles_virus R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 49/2735 52/10654 7.863991606659239e-26 9.450586404493999e-25 4.763415045215568e-25 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 49 Measles_virus R-HSA-4641258 Degradation of DVL 52/2735 57/10654 1.3663813653515088e-25 1.6277760613317975e-24 8.204541653735375e-25 5718/5689/5684/5720/5682/5700/122706/5707/1856/5690/5717/9491/23198/143471/5706/5705/10197/8452/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/1857/7311/5694/5693/5721/5696/5691/7314 52 Measles_virus R-HSA-8948751 Regulation of PTEN stability and activity 59/2735 69/10654 1.758236865525738e-25 2.0765383670433284e-24 1.0466455388247587e-24 5718/5689/5684/5720/5682/5700/122706/5707/10273/207/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/4734/5714/11060/9861/81847/5715/5711/5701/5688/5687/5685/5683/5698/5708/10000/5692/5686/5713/5728/5699/2444/5710/5702/8975/5719/208/5704/6233/5716/7311/5694/5693/5721/5696/23608/5691/7314 59 Measles_virus R-HSA-180585 Vif-mediated degradation of APOBEC3G 50/2735 54/10654 2.142483251677719e-25 2.5087197049559616e-24 1.2644795439501426e-24 5718/5689/5684/8065/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Measles_virus R-HSA-9013694 Signaling by NOTCH4 66/2735 82/10654 2.537701085244406e-25 2.946313971851556e-24 1.4850418482786172e-24 8454/5718/5689/5684/5720/5682/5700/5707/23462/207/5690/55534/3280/5717/9491/6500/84441/23385/5706/5705/10197/10460/10046/7534/7316/10213/5709/9978/5695/102/5714/9861/5715/22938/5711/5701/5688/1387/5687/4088/5685/5683/5698/59/5708/5692/5686/5713/2033/55294/5699/5710/5702/5719/9794/5704/6233/5716/7311/5694/3516/5693/5721/5696/5691/7314 66 Measles_virus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 57/2735 66/10654 3.988837001095083e-25 4.592190497059045e-24 2.314619259370521e-24 5718/5689/5684/5720/5682/112399/5700/122706/7321/5707/84962/5690/5717/9491/23198/143471/5706/5705/10197/7323/7316/10213/5709/9978/5695/5714/9861/7322/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/7428/5702/8453/5719/5704/6233/5716/7311/54583/5694/5693/5721/5696/5691/7314 57 Measles_virus R-HSA-1234174 Cellular response to hypoxia 62/2735 75/10654 4.474947149275858e-25 5.10889799542327e-24 2.5750573069517215e-24 5718/5689/5684/5720/5682/112399/5700/122706/7321/5707/84962/7422/5690/5717/9491/23198/143471/5706/5705/10197/7323/7316/10213/5709/9978/5695/5714/9861/7322/5715/5711/5701/5688/1387/5687/5685/5683/5698/5708/5692/5686/5713/2033/5699/5710/25994/7428/5702/8453/5719/5704/6233/2056/5716/7311/54583/5694/5693/5721/5696/5691/7314 62 Measles_virus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 63/2735 77/10654 5.63209764222144e-25 6.376837826316837e-24 3.2141418471485554e-24 5718/5689/5684/5720/5682/51512/5700/122706/5707/5690/10382/5717/9491/23198/7277/143471/5706/9133/10381/5705/10197/7316/10213/5709/891/5695/983/1026/5714/9861/5715/5711/5701/5688/5687/7846/5685/5683/5698/5708/3320/22919/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/3326/5716/7311/10383/5347/5694/5693/5721/5696/5691/7314 63 Measles_virus R-HSA-68867 Assembly of the pre-replicative complex 58/2735 68/10654 5.951232456613497e-25 6.682941365213517e-24 3.36842837923939e-24 5718/4172/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/4173/143471/5706/5705/10197/7316/10213/5709/1869/4174/5695/5714/4171/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/990/5713/5699/4175/5710/81620/5702/5719/5704/6233/5716/23595/7311/5694/5693/5721/5696/5691/4176/7314 58 Measles_virus R-HSA-9607240 FLT3 Signaling 146/2735 267/10654 1.7020781315963976e-24 1.8958106018594023e-23 9.55552635282188e-24 5295/54106/5718/818/5689/5170/815/5684/2674/4893/6464/6711/5290/5720/1437/3667/71/5682/1844/5291/2065/3561/5525/5747/5700/3815/122706/5707/5526/817/1849/5690/7010/1439/5594/2322/5717/8074/9491/23198/409/7414/10817/143471/5706/2064/57761/5921/5705/10197/1438/8452/6776/5528/7316/10213/5709/673/9978/1950/3560/5695/5140/2263/5289/4233/3055/84078/3718/5714/6714/9861/5715/6710/5519/5711/2261/5701/5688/5159/5687/3558/3717/5685/2244/5683/5698/5708/3084/5692/5686/5713/2335/2534/408/5699/5529/1445/5710/816/5702/5894/5719/3563/208/1742/5704/6233/5527/2885/6709/3716/5716/88/2266/8660/7311/8826/5518/5155/2243/7450/1956/60/4254/5296/117145/3845/6777/5694/3265/3559/369/801/5781/5693/5721/5696/5691/5245/7529/5156/7314/5595/5515/5516 146 Measles_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 50/2735 55/10654 1.7717808691355097e-24 1.957532089286813e-23 9.866623515729153e-24 1147/834/9447/596/351/4790/6885/842/10392/8767/10910/58484/7295/330/23118/29108/841/8517/7316/7335/5970/22861/5027/64127/7128/1432/329/837/598/10628/3656/5603/10454/83737/3654/7189/6233/3326/4210/7311/114548/5600/7334/1540/3551/6300/5608/4791/7314/257397 50 Measles_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 64/2735 80/10654 2.57653207046855e-24 2.823879149233531e-23 1.423330558507258e-23 23165/3837/3838/5903/402569/5335/55706/7175/9631/2316/4600/348995/9636/79023/57122/23636/11274/8638/25820/1982/7706/10762/23511/7316/53371/4734/3434/6772/23279/4927/9688/79902/23586/6041/9883/4939/6059/23225/1981/1973/3661/8086/7324/3836/9246/51191/4599/6233/3716/7311/9972/7318/5610/5300/8021/4940/6396/129401/7334/4938/55746/8480/7314/5595 64 Measles_virus R-HSA-5689880 Ub-specific processing proteases 127/2735 220/10654 2.605532758116464e-24 2.832999903666314e-23 1.4279277270880538e-23 9960/5718/23358/5689/10600/23032/5684/8295/5720/7186/645836/6885/5682/90865/5700/122706/5707/991/8737/8237/5690/55611/2625/9817/4303/100287364/91833/5717/9491/57646/23198/63967/409/6478/1080/330/9101/143471/5706/100287513/5705/57695/11274/55031/27005/10197/8517/64750/7416/7316/10213/5709/993/5695/890/7417/4792/9738/9986/5714/8678/4609/392188/9861/23586/81847/5715/100287144/64426/100287441/5711/3416/5701/5688/329/5687/6502/9099/4088/5685/5683/5698/5708/9146/5692/5686/5713/408/64135/5728/5699/5710/10454/100287327/5702/7157/8900/9958/8313/8975/4087/10868/63891/5719/7189/57599/5704/6233/377630/5716/100287478/9804/7311/728386/1540/5694/100287404/5693/154/5721/100287178/5696/5691/100287205/7314/4193/100287238 127 Measles_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 68/2735 88/10654 3.7915263619823295e-24 4.090071744815584e-23 2.0615344330380504e-23 5718/3303/5689/5684/5720/5682/5700/122706/5707/3842/207/5690/3184/5717/9491/3315/23198/143471/5706/5705/10197/7534/7316/10213/5709/5695/9261/5714/9861/5715/5711/1432/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/1981/5699/5710/5702/5719/5704/6233/5580/5716/7514/7311/8021/54464/5600/5694/3304/3312/5693/5721/5696/5691/167227/7529/22894/7314/1994 68 Measles_virus R-HSA-5683057 MAPK family signaling cascades 155/2735 294/10654 9.968698339694533e-24 1.0669622441704304e-22 5.377850420098366e-23 5718/2308/818/5689/3725/815/5684/2674/4893/6464/6711/5720/1437/3667/71/2309/5682/1844/2065/3561/5525/5747/5700/3815/122706/5707/5526/817/1849/5690/7010/1439/5594/2322/5717/8074/9491/3315/23198/409/7414/10817/143471/5706/2064/5921/5705/10197/3337/1438/192670/5596/8452/5528/7316/10213/5709/673/9978/1950/3560/5695/2263/4233/983/5597/84078/3718/5714/6714/4609/9861/5566/5715/6710/5519/5711/2261/5701/5688/5159/5687/3558/3717/5685/2244/5683/5698/5708/3084/5692/5686/5713/2335/2534/408/5699/5529/1445/5710/816/8555/5702/998/5894/8556/5719/3563/1742/5704/6233/5527/2885/6709/3716/5716/88/2266/8660/7514/7311/8826/5518/5155/2243/7450/1956/60/4254/4343/3570/3845/5694/3265/3559/5058/369/801/7297/5781/3569/5062/5693/5721/5696/5691/5245/7529/5156/7314/3572/5879/5595/5515/5516 155 Measles_virus R-HSA-69002 DNA Replication Pre-Initiation 66/2735 85/10654 1.0983867020720932e-23 1.166503706851758e-22 5.879573044139479e-23 5718/1017/4172/6118/5689/5684/5720/8318/5682/5700/122706/5707/8317/5690/5717/9491/23198/4173/143471/5706/5705/10197/7316/10213/5709/5422/1869/4174/5695/5714/4171/9861/5715/6119/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/990/5713/5699/4175/5710/81620/5702/5719/5704/6233/55388/5716/23595/7311/6117/5694/5693/5721/5696/5691/4176/7314 66 Measles_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 71/2735 95/10654 1.2327781551422883e-23 1.2892412767518586e-22 6.498211890504951e-23 8454/23643/1147/3725/8945/1326/351/4790/6885/11213/10392/8767/1849/5594/4214/6500/51295/23118/10333/7099/8517/4615/5528/7316/7335/5970/7096/4792/9261/59307/4793/177/8651/3146/5519/64127/5598/1432/23291/929/114609/3656/10454/6288/695/3654/7189/6285/6233/948/51135/1385/2353/7311/5518/1386/6197/5599/5600/7334/7097/3551/6416/5608/4791/51231/7314/5595/5515/257397/5516 71 Measles_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 71/2735 95/10654 1.2327781551422883e-23 1.2892412767518586e-22 6.498211890504951e-23 8454/23643/1147/3725/8945/1326/351/4790/6885/11213/10392/8767/1849/5594/4214/6500/51295/23118/10333/7099/8517/4615/5528/7316/7335/5970/7096/4792/9261/59307/4793/177/8651/3146/5519/64127/5598/1432/23291/929/114609/3656/10454/6288/695/3654/7189/6285/6233/948/51135/1385/2353/7311/5518/1386/6197/5599/5600/7334/7097/3551/6416/5608/4791/51231/7314/5595/5515/257397/5516 71 Measles_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 72/2735 98/10654 3.420509185506679e-23 3.5233816422136473e-22 1.7759034631518652e-22 8454/23643/1147/3725/8945/1326/351/4790/6885/11213/10392/653509/8767/1849/5594/4214/6500/51295/23118/10333/7099/8517/4615/5528/7316/7335/5970/7096/4792/9261/59307/4793/177/8651/3146/5519/64127/5598/1432/23291/929/114609/3656/10454/6288/695/3654/7189/6285/6233/948/51135/1385/2353/7311/5518/1386/6197/5599/5600/7334/7097/3551/6416/5608/4791/51231/7314/5595/5515/257397/5516 72 Measles_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 72/2735 98/10654 3.420509185506679e-23 3.5233816422136473e-22 1.7759034631518652e-22 8454/23643/1147/3725/8945/1326/351/4790/6885/11213/10392/653509/8767/1849/5594/4214/6500/51295/23118/10333/7099/8517/4615/5528/7316/7335/5970/7096/4792/9261/59307/4793/177/8651/3146/5519/64127/5598/1432/23291/929/114609/3656/10454/6288/695/3654/7189/6285/6233/948/51135/1385/2353/7311/5518/1386/6197/5599/5600/7334/7097/3551/6416/5608/4791/51231/7314/5595/5515/257397/5516 72 Measles_virus R-HSA-5687128 MAPK6/MAPK4 signaling 67/2735 89/10654 1.11312256342681e-22 1.1380432178318879e-21 5.736122557800372e-22 5718/2308/5689/3725/5684/5720/2309/5682/5700/122706/5707/5690/5717/9491/3315/23198/143471/5706/5705/10197/3337/192670/5596/7316/10213/5709/5695/983/5597/5714/4609/9861/5566/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/8555/5702/998/8556/5719/5704/6233/5716/7514/7311/4343/5694/5058/5062/5693/5721/5696/5691/7314/5879 67 Measles_virus R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 51/2735 59/10654 1.214820931461684e-22 1.2328182785944498e-21 6.213820904786469e-22 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/990/5713/5699/5710/81620/5702/5719/5704/6233/5716/23595/7311/5694/5693/5721/5696/5691/7314 51 Measles_virus R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 46/2735 51/10654 2.905571718255957e-22 2.92693621618431e-21 1.4752748043157182e-21 5718/5689/5684/1728/5720/5682/5700/122706/5707/5690/51686/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/5694/5693/5721/5696/5691 46 Measles_virus R-HSA-5684996 MAPK1/MAPK3 signaling 137/2735 255/10654 4.316469400696065e-22 4.3164694006960654e-21 2.175646505460329e-21 5718/818/5689/815/5684/2674/4893/6464/6711/5720/1437/3667/71/5682/1844/2065/3561/5525/5747/5700/3815/122706/5707/5526/817/1849/5690/7010/1439/5594/2322/5717/8074/9491/23198/409/7414/10817/143471/5706/2064/5921/5705/10197/1438/8452/5528/7316/10213/5709/673/9978/1950/3560/5695/2263/4233/983/84078/3718/5714/6714/9861/5715/6710/5519/5711/2261/5701/5688/5159/5687/3558/3717/5685/2244/5683/5698/5708/3084/5692/5686/5713/2335/2534/408/5699/5529/1445/5710/816/5702/5894/5719/3563/1742/5704/6233/5527/2885/6709/3716/5716/88/2266/8660/7311/8826/5518/5155/2243/7450/1956/60/4254/3570/3845/5694/3265/3559/369/801/7297/5781/3569/5693/5721/5696/5691/5245/7529/5156/7314/3572/5595/5515/5516 137 Measles_virus R-HSA-373076 Class A/1 (Rhodopsin-like receptors) 167/2735 335/10654 4.694342639678999e-22 4.660325664029151e-21 2.348961686978965e-21 729230/151/57007/10316/10803/4544/4543/10663/4889/1880/9283/727/351/11251/7852/9294/3352/8484/10161/117579/283869/338442/3579/4986/2492/23566/6351/2358/64805/6752/6374/1237/5539/1903/2852/84539/1230/5179/3354/6753/3358/2841/4886/2919/3577/51289/5368/6754/27202/8862/2150/301/8811/3576/56670/5196/6360/3827/150/5173/56923/2832/2693/2357/4985/27199/2920/2826/2921/1236/2853/6352/140/6751/6376/165140/27198/5443/6348/186/3627/53637/2840/2831/3361/6346/152/6364/7253/5367/10563/134/5540/4988/1901/6370/58191/5030/5697/6755/1524/5733/256933/1129/7252/643/10850/51083/3355/624/3351/2796/4852/1233/6288/6372/6366/185/339403/2861/728/183/10022/5473/4283/8843/719/2847/6363/6373/57121/4987/2833/6347/1268/9290/11255/9170/187/1132/2359/1814/10874/6357/6750/8698/56477/5660/1815/2587/1325/53829/1232/9934/1902/3350/129521/154/1234/1269/59340/1813/50865/4887/718/6387/623 167 Measles_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 68/2735 93/10654 8.89727767138868e-22 8.706621721287494e-21 4.3884316935571225e-21 54106/8454/23643/1147/3665/3725/8945/1326/351/4790/6885/10392/8767/1849/5594/4214/6500/51295/23118/7099/8517/4615/5528/7316/7335/5970/4792/9261/4793/177/3146/5519/64127/5598/1432/23291/929/3656/10454/6288/3654/7189/6285/6233/51311/51135/1385/2353/7311/5518/1386/6197/5599/353376/5600/7334/3551/6416/5608/4791/51231/51284/7314/5595/5515/148022/257397/5516 68 Measles_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 68/2735 93/10654 8.89727767138868e-22 8.706621721287494e-21 4.3884316935571225e-21 54106/8454/23643/1147/3665/3725/8945/1326/351/4790/6885/10392/8767/1849/5594/4214/6500/51295/23118/7099/8517/4615/5528/7316/7335/5970/4792/9261/4793/177/3146/5519/64127/5598/1432/23291/929/3656/10454/6288/3654/7189/6285/6233/51311/51135/1385/2353/7311/5518/1386/6197/5599/353376/5600/7334/3551/6416/5608/4791/51231/51284/7314/5595/5515/148022/257397/5516 68 Measles_virus R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 45/2735 50/10654 1.0339292992956026e-21 1.0045979716560111e-20 5.06351340304528e-21 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/5694/5693/5721/5696/5691/4360 45 Measles_virus R-HSA-5658442 Regulation of RAS by GAPs 55/2735 68/10654 1.6892361629870111e-21 1.6297560164029614e-20 8.214521296660335e-21 5718/5689/5684/4893/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5921/5705/10197/8452/7316/10213/5709/9978/5695/84078/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/3845/5694/3265/5693/5721/5696/5691/7314 55 Measles_virus R-HSA-5610787 Hedgehog 'off' state 77/2735 113/10654 2.1533330003311055e-21 2.0629833639535767e-20 1.0398133590115607e-20 8454/5718/5689/8945/5684/5720/5682/54903/5700/122706/5707/1452/5690/10382/5717/9491/6500/23198/112/7277/143471/114/5706/10381/5705/7289/10197/108/113/7316/10213/5709/9978/5695/2778/5727/111/107/5714/9861/5566/5715/5711/2932/5701/5688/5687/7846/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/83737/5719/5577/5704/6233/5716/7311/10383/23322/196883/115/5694/8481/5693/5721/5696/109/5691/7314 77 Measles_virus R-HSA-1169408 ISG15 antiviral mechanism 57/2735 72/10654 2.246087021402477e-21 2.1369022356398567e-20 1.0770709693275036e-20 23165/3837/3838/5903/402569/5335/55706/7175/9631/4600/348995/9636/79023/57122/23636/11274/25820/1982/7706/10762/23511/7316/53371/4734/3434/6772/23279/4927/9688/79902/23586/9883/23225/1981/1973/3661/8086/7324/3836/9246/51191/4599/6233/3716/7311/9972/7318/5610/5300/8021/6396/129401/7334/55746/8480/7314/5595 57 Measles_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 67/2735 92/10654 2.580721432276246e-21 2.4383368015299704e-20 1.2290041811783792e-20 54106/8454/23643/1147/3725/8945/1326/351/4790/6885/10392/8767/1849/5594/4214/6500/51295/23118/7099/8517/4615/5528/7316/7335/5970/4792/9261/4793/177/3146/5519/64127/5598/1432/23291/929/3656/10454/6288/3654/7189/6285/6233/51311/51135/1385/2353/7311/5518/1386/6197/5599/353376/5600/7334/3551/6416/5608/4791/51231/51284/7314/5595/5515/148022/257397/5516 67 Measles_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 69/2735 97/10654 5.8379585837847085e-21 5.478084424510308e-20 2.7611397483509504e-20 54106/8454/23643/1147/3665/3725/8945/1326/351/4790/6885/10392/8767/1849/5594/4214/6500/51295/23118/7099/8517/4615/5528/7316/7335/5970/4792/5289/9261/4793/177/3146/5519/64127/5598/1432/23291/929/3656/10454/6288/3654/7189/6285/6233/51311/51135/1385/2353/7311/5518/1386/6197/5599/353376/5600/7334/3551/6416/5608/4791/51231/51284/7314/5595/5515/148022/257397/5516 69 Measles_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 74/2735 108/10654 7.850277691901417e-21 7.316245195853702e-20 3.687634920076856e-20 5295/3605/7124/2308/7291/596/9655/2208/3592/3566/2309/3561/7412/7184/3593/207/3684/9021/7422/3553/2625/5743/4318/3383/301/6657/6778/3576/332/3662/3597/3688/3565/4985/6774/5443/1026/3718/7133/3606/6772/8651/4609/149233/4988/1901/3552/3717/598/3320/4843/2335/6288/7157/948/3716/2353/604/6347/7076/7040/3687/51561/3570/7431/5008/3312/3929/7297/3569/3162/3689/3586/3596 74 Measles_virus R-HSA-5358351 Signaling by Hedgehog 92/2735 149/10654 9.866116670669455e-21 9.132824215416995e-20 4.603252159288166e-20 8454/57154/5718/5689/8945/5684/5720/5682/54903/5700/122706/5707/10956/1452/5690/10382/5717/9491/6500/23198/409/79577/112/7277/143471/114/5706/10381/5705/7289/10197/108/64750/113/8452/84447/7316/10213/5709/9978/5695/2778/5727/111/107/5714/50846/7415/9861/5566/5715/5711/2932/5701/5688/5687/7846/5685/5683/5698/5708/5692/5686/5713/408/5699/6400/5710/5702/83737/5719/5577/5704/6233/5716/7311/51009/27248/147111/10383/23322/196883/115/5694/8481/5693/5721/5696/109/5691/5034/7314 92 Measles_virus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 71/2735 102/10654 1.1733878858428068e-20 1.078886848056809e-19 5.437954455053911e-20 8454/7124/1147/5718/5689/8945/23495/5684/8744/5720/7186/5682/5700/122706/5707/8600/5690/9039/5717/9491/6500/23198/330/143471/5706/5705/10197/10673/7316/10213/5709/5695/9020/7133/5714/9861/5715/5711/7132/5701/5688/329/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/7187/958/5694/5693/5721/5696/5691/4791/959/7314/4055 71 Measles_virus R-HSA-4608870 Asymmetric localization of PCP proteins 52/2735 64/10654 1.454421390111679e-20 1.328371536302e-19 6.695441627461484e-20 57154/5718/5689/5684/5720/5682/5700/122706/5707/1856/5690/5717/9491/23198/143471/5706/5705/10197/64750/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/23513/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 52 Measles_virus R-HSA-5673001 RAF/MAP kinase cascade 131/2735 249/10654 4.1059070891938116e-20 3.7252269617188884e-19 1.8776403279966121e-19 5718/818/5689/815/5684/2674/4893/6464/6711/5720/1437/3667/71/5682/1844/2065/3561/5525/5747/5700/3815/122706/5707/5526/817/1849/5690/7010/1439/5594/2322/5717/8074/9491/23198/409/7414/10817/143471/5706/2064/5921/5705/10197/1438/8452/5528/7316/10213/5709/673/9978/1950/3560/5695/2263/4233/84078/3718/5714/6714/9861/5715/6710/5519/5711/2261/5701/5688/5159/5687/3558/3717/5685/2244/5683/5698/5708/3084/5692/5686/5713/2335/2534/408/5699/5529/1445/5710/816/5702/5894/5719/3563/1742/5704/6233/5527/2885/6709/3716/5716/88/2266/8660/7311/8826/5518/5155/2243/7450/1956/60/4254/3845/5694/3265/3559/369/801/5693/5721/5696/5691/5245/7529/5156/7314/5595/5515/5516 131 Measles_virus R-HSA-69481 G2/M Checkpoints 99/2735 168/10654 4.2037508491792724e-20 3.7889070153786863e-19 1.9097372278819961e-19 5718/1017/4172/6118/5689/5684/5720/8318/5682/9156/7531/51512/5700/122706/5707/7532/8317/10971/5690/51588/5717/9491/23198/63967/7533/2810/4173/11200/143471/545/5706/9133/472/5705/10197/7336/7534/580/11073/29086/7316/10213/5709/4174/891/993/5695/983/641/5714/4171/9861/5715/9656/9088/6119/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/990/5713/995/5699/4175/5710/1111/5702/7157/5719/8924/5704/6233/55388/5716/672/5932/7158/23595/7311/79184/7156/6117/7334/5694/7465/5693/5721/5696/5691/4176/7529/7314 99 Measles_virus R-HSA-375276 Peptide ligand-binding receptors 112/2735 201/10654 6.574969717424516e-20 5.8873911848833905e-19 2.967444193072227e-19 729230/57007/10316/10803/10663/4889/9283/727/351/7852/8484/117579/283869/3579/4986/6351/2358/6752/6374/1237/5539/2852/84539/1230/5179/6753/4886/2919/3577/51289/5368/6754/27202/8862/2150/301/8811/3576/5196/6360/3827/5173/56923/2832/2693/2357/4985/2920/2826/2921/1236/6352/6751/6376/5443/6348/186/3627/2831/6346/6364/5367/10563/5540/4988/6370/58191/5697/6755/1524/256933/643/10850/51083/624/4852/1233/6288/6372/6366/185/339403/2861/728/183/10022/5473/4283/719/2847/6363/6373/4987/2833/6347/187/2359/10874/6357/6750/56477/5660/2587/1325/1232/129521/1234/50865/4887/718/6387/623 112 Measles_virus R-HSA-5619084 ABC transporter disorders 58/2735 77/10654 7.961700717129307e-20 7.037116117720742e-19 3.546944428140459e-19 5718/5689/5684/5720/5682/5700/122706/5707/10956/5690/64241/5717/9491/23198/1080/143471/91319/5706/5705/10197/7316/10213/5709/335/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/6400/5710/5702/5719/5704/6233/5716/7311/51009/27248/11160/5694/5693/5721/5696/5691/7314 58 Measles_virus R-HSA-9009391 Extra-nuclear estrogen signaling 58/2735 77/10654 7.961700717129307e-20 7.037116117720742e-19 3.546944428140459e-19 5295/2788/5170/596/5590/4893/6464/857/5290/54331/2309/5747/59345/2770/207/1903/5594/6722/1027/3315/10681/51764/94235/4318/2100/1950/55970/2792/346562/6714/2099/8503/2793/10000/3320/2785/4846/2783/2784/2782/2786/2771/208/7514/1385/2353/1956/5296/3845/3276/3265/801/3480/2791/2773/5595/2790/2787 58 Measles_virus R-HSA-195258 RHO GTPase Effectors 158/2735 327/10654 3.231566644373008e-19 2.8379783992250138e-18 1.4304370571583626e-18 220134/5170/5905/55839/11130/4688/25/79682/5590/5903/10403/54908/71/6249/55143/1495/1499/55055/25936/5525/9735/7531/5747/80776/4690/1783/1058/4659/991/1856/401541/79019/5526/4627/2316/7532/10971/348235/80152/4771/10382/9212/5594/1063/6722/8379/1027/3619/79172/1080/7533/2810/147841/7277/348995/23421/79023/55920/10381/57122/79980/64105/6280/30851/6232/7534/332/1780/23122/5528/3688/5048/1781/5501/57405/10398/8655/4085/5289/5216/6279/6714/23279/55166/79902/3796/54821/5519/9183/1432/2017/81565/2491/1062/699/7846/999/752/22919/9475/1060/91687/995/3895/79003/5529/51143/998/4628/23028/695/83540/11004/354/1742/5527/2885/10096/5580/701/10097/1857/9055/7514/9184/9928/8826/5518/10383/54820/5347/387/57551/60/5300/84643/6396/5600/23332/25909/5058/801/64946/9793/10726/1536/81930/5062/55746/140735/5500/7529/5879/4221/5595/5515/1778/5516 158 Measles_virus R-HSA-5689603 UCH proteinases 69/2735 102/10654 4.91471285134686e-19 4.288634781111591e-18 2.1616169161807173e-18 5718/5689/5684/5720/114785/3607/221937/5682/5700/122706/5707/51377/171023/4738/5690/10445/5717/9491/23198/143471/5706/5705/10197/580/7316/10213/5709/5695/8314/55252/5714/9861/5715/5711/5701/5688/5687/7347/5685/5683/5698/5708/5692/5686/5713/55777/221656/5699/5710/8473/5702/9958/5719/5704/6233/5716/7048/7311/60/7040/7345/3054/5694/5693/5721/5696/5691/7314/7528 69 Measles_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 61/2735 85/10654 5.419725853566334e-19 4.640640262116174e-18 2.339039578907576e-18 8454/1147/3725/8945/1326/351/81793/4790/6885/10392/8767/1849/5594/4214/6500/51295/23118/8517/4615/7100/5528/7316/7335/5970/4792/9261/4793/177/3146/5519/64127/5598/1432/23291/3656/10454/6288/3654/7189/6285/6233/51135/1385/2353/7311/5518/1386/6197/5599/5600/7334/3551/6416/5608/4791/51231/7314/5595/5515/257397/5516 61 Measles_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 61/2735 85/10654 5.419725853566334e-19 4.640640262116174e-18 2.339039578907576e-18 8454/1147/3725/8945/1326/351/81793/4790/6885/10392/8767/1849/5594/4214/6500/51295/23118/8517/4615/7100/5528/7316/7335/5970/4792/9261/4793/177/3146/5519/64127/5598/1432/23291/3656/10454/6288/3654/7189/6285/6233/51135/1385/2353/7311/5518/1386/6197/5599/5600/7334/3551/6416/5608/4791/51231/7314/5595/5515/257397/5516 61 Measles_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 61/2735 85/10654 5.419725853566334e-19 4.640640262116174e-18 2.339039578907576e-18 8454/1147/3725/8945/1326/351/81793/4790/6885/10392/8767/1849/5594/4214/6500/51295/23118/8517/4615/7100/5528/7316/7335/5970/4792/9261/4793/177/3146/5519/64127/5598/1432/23291/3656/10454/6288/3654/7189/6285/6233/51135/1385/2353/7311/5518/1386/6197/5599/5600/7334/3551/6416/5608/4791/51231/7314/5595/5515/257397/5516 61 Measles_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 33/2735 34/10654 7.200499621741141e-19 6.127133218500226e-18 3.0882822830089495e-18 7321/9140/29110/57506/9636/54476/7706/84166/7323/9474/7316/3093/23586/7322/7128/64135/54941/83737/3661/9246/51191/6233/7311/55593/84282/7318/79671/5094/7187/5300/9641/1540/7314 33 Measles_virus R-HSA-6798695 Neutrophil degranulation 209/2735 480/10654 2.499406649871573e-18 2.113695747113614e-17 1.0653741145651408e-17 10450/2717/25801/10694/5718/1828/2512/3303/58485/9798/23352/1727/5689/2934/5777/3837/23412/7276/4893/5036/5284/5005/29099/4790/327/83858/3240/960/4332/7305/1823/1511/5657/3579/1915/8635/3107/5707/2358/203068/1650/5199/23197/3684/79888/383/387921/1991/5594/6317/54472/8836/5717/2919/3577/55860/7414/1378/2760/10533/29108/23385/4318/3958/79980/4257/6280/5788/10577/1604/2517/11240/2357/10213/5709/10576/5695/8804/6278/2896/966/5611/8655/5834/5799/567/102/6279/7133/2799/5768/1471/9588/29952/4069/7415/3106/3146/9861/3074/79792/410/4353/170482/2548/1432/411/11010/5701/3920/6836/9342/197/140885/2171/3310/5476/5683/929/5265/55832/5708/3320/55313/201294/5686/5713/388697/2588/23593/2495/3728/3614/80142/175/2444/820/51143/5702/6386/4125/566/5478/51552/5719/10075/56729/728/6402/10487/51071/5473/3326/948/5580/684/6709/10857/1520/10097/1675/3916/3685/719/93100/47/8826/81567/9522/302/10383/387/3687/5236/6036/353376/3608/51806/80184/2720/7097/3304/3312/64114/5660/2040/2547/10493/1536/387263/10970/2990/3689/2665/7879/1075/8907/53916/5645/671/1508/114790/2519/6037/5879/51316/2950/1778/718 209 Measles_virus R-HSA-76002 Platelet activation, signaling and aggregation 132/2735 262/10654 3.747642700223865e-18 3.1498592020286474e-17 1.5876355255711045e-17 5295/2788/151/928/5170/5777/5590/351/6464/5290/54331/5005/7018/2153/5770/5291/5340/5747/59345/51097/64805/2770/5336/2316/207/813/3959/7422/5594/10681/409/7414/51764/7277/94235/334/29106/7534/5196/10447/3827/150/1950/335/51706/55970/2621/308/5216/6850/2792/5768/346562/6714/710/6694/3671/152/6647/7273/1191/8503/4352/146850/1432/3920/27154/2793/197/4067/23533/374354/2244/81/5265/3309/9948/2335/5294/2534/408/2785/2783/2784/1445/2782/998/5894/5478/2786/2771/2/10487/22915/2885/1398/5473/7410/948/5580/88/2266/7409/8407/1675/7873/3932/7076/3479/5155/2243/7450/387/5296/5581/51368/7040/9564/10916/213/5660/801/5781/2791/2773/5879/5595/2790/2814/2787/139322/7066 132 Measles_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 41/2735 48/10654 4.9152221615877694e-18 4.1060087569361247e-17 2.0695672259316925e-17 5295/5777/3635/6464/5290/1437/5291/3561/1439/1438/7534/6776/7316/3560/3055/6850/3718/5566/8503/867/3558/4067/3717/3636/2534/3563/6233/2885/7525/1398/7006/3716/7409/7311/5293/5296/6777/1399/3559/5781/7314 41 Measles_virus R-HSA-1852241 Organelle biogenesis and maintenance 144/2735 296/10654 6.079645192167497e-18 5.0479478262239214e-17 2.5443363611240053e-17 115106/10694/22995/55559/4899/79867/8841/55735/79718/11258/22981/8636/7531/10142/54903/80776/11190/203068/3842/3418/54801/7532/55125/1454/112752/10382/85302/6753/51134/23410/95681/121441/7277/200186/79441/10013/79969/10381/5116/3313/54806/5465/9814/91147/5048/1781/23354/10576/80321/2553/8766/9611/5469/22832/10989/146057/8655/9738/79598/54927/983/1639/54205/84303/55722/4957/10121/9702/5566/64784/79959/132320/347240/84131/1432/1387/25813/7846/7840/6907/7283/4580/3320/22919/2101/27077/22994/11064/4867/79600/10540/84902/10733/1069/6256/4751/10651/117177/5577/80254/1385/57545/2847/26005/54930/5518/26123/10383/1386/55835/54820/5347/23322/6742/378/5600/3054/9662/80184/55142/23332/1453/22897/5564/6300/801/9793/4218/5108/133522/261734/7019/8648/8481/57787/140735/93323/10806/51259/55755/9657/10891/1778/139322 144 Measles_virus R-HSA-420499 Class C/3 (Metabotropic glutamate/pheromone receptors) 35/2735 38/10654 6.549536735431161e-18 5.405340558759452e-17 2.7244743807500576e-17 2913/50833/338398/5726/2916/259293/259287/2550/50836/50832/846/2918/259294/259290/2912/259295/9568/54429/80834/259292/50834/259285/50838/2914/2917/50831/50839/83756/80835/259296/259289/50835/50840/259286/50837 35 Measles_virus R-HSA-3858494 Beta-catenin independent WNT signaling 86/2735 146/10654 1.2902175116159963e-17 1.0584419107268952e-16 5.3349050590614156e-17 2788/57154/5718/5689/1173/815/5684/5720/54331/6885/5682/1499/59345/4772/5700/122706/5707/1856/5690/5717/9491/23198/10681/409/51764/94235/143471/5706/5705/10197/192670/64750/7316/10213/5709/5695/55970/54361/5216/2792/5714/9861/5715/5881/5711/5701/5688/2793/5687/5685/5683/5698/5708/5692/5686/5713/2785/5699/2783/2784/5710/2782/5702/2786/5719/23513/5704/6233/5716/1857/163/7311/387/4343/3845/5694/801/5693/5721/2791/5696/5691/7314/5879/2790/2787 86 Measles_virus R-HSA-6783783 Interleukin-10 signaling 40/2735 47/10654 1.6548294950504205e-17 1.349474052511355e-16 6.801805443315012e-17 729230/3557/7124/2208/3592/1437/3587/6351/3593/3553/1230/2919/5743/941/3383/3576/2357/2920/6352/6774/1435/6348/1440/3627/7133/3606/6364/7132/3552/942/3716/6363/6347/7076/3588/7297/3569/1234/3586/3554 40 Measles_virus R-HSA-5632684 Hedgehog 'on' state 59/2735 85/10654 2.7053577185887873e-17 2.193100635779076e-16 1.1053968629051662e-16 57154/5718/5689/5684/5720/5682/5700/122706/5707/1452/5690/5717/9491/23198/409/79577/143471/5706/5705/10197/64750/8452/7316/10213/5709/9978/5695/5727/5714/50846/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/408/5699/5710/5702/83737/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 59 Measles_virus R-HSA-351202 Metabolism of polyamines 46/2735 59/10654 5.12229402590969e-17 4.1279663620566324e-16 2.0806346012363816e-16 5718/5689/5684/1728/5720/5682/5700/122706/5707/5690/51686/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/5694/5693/5721/5696/5691 46 Measles_virus R-HSA-168638 NOD1/2 Signaling Pathway 33/2735 36/10654 8.57725498476203e-17 6.871835864984785e-16 3.463637593107966e-16 1147/834/6885/842/10392/8767/330/23118/841/8517/7316/7335/64127/7128/1432/329/837/3656/5603/10454/83737/3654/7189/6233/7311/5600/7334/1540/3551/6300/5608/7314/257397 33 Measles_virus R-HSA-389356 CD28 co-stimulation 31/2735 33/10654 1.3012927525929347e-16 1.036494808751349e-15 5.224284245415943e-16 5295/5170/1326/5290/207/941/57761/9020/55615/6714/64223/8503/4067/10000/2534/998/942/208/2885/7525/79109/2475/7409/3932/5296/117145/5058/5062/940/5879/253260 31 Measles_virus R-HSA-5617833 Cilium Assembly 106/2735 201/10654 1.3290454025108348e-16 1.0524810412947072e-15 5.30486026192338e-16 115106/10694/22995/55559/79867/11258/22981/8636/7531/10142/54903/80776/11190/203068/3842/54801/7532/55125/1454/112752/10382/85302/6753/51134/95681/121441/7277/79441/10013/79969/10381/5116/54806/9814/91147/5048/1781/23354/10576/80321/8766/22832/146057/8655/9738/79598/983/1639/55722/4957/10121/9702/5566/79959/132320/347240/84131/7846/7840/7283/3320/22919/27077/22994/11064/4867/79600/10540/84902/10733/1069/4751/117177/5577/80254/57545/2847/26005/54930/5518/26123/10383/55835/54820/5347/23322/378/9662/80184/55142/23332/1453/22897/9793/4218/5108/261734/8481/57787/140735/93323/10806/51259/55755/9657/1778 106 Measles_virus R-HSA-4086400 PCP/CE pathway 61/2735 92/10654 2.4484416148989575e-16 1.9277959841445815e-15 9.716743492883945e-16 57154/5718/5689/1173/5684/5720/5682/5700/122706/5707/1856/5690/5717/9491/23198/409/143471/5706/5705/10197/64750/7316/10213/5709/5695/54361/5216/5714/9861/5715/5881/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/23513/5704/6233/5716/1857/163/7311/387/5694/5693/5721/5696/5691/7314/5879 61 Measles_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 98/2735 182/10654 3.1106360921112777e-16 2.435183683538543e-15 1.227414903112781e-15 1912/23165/23468/7150/5905/5903/55706/7175/1487/55143/9631/3622/5468/9112/1786/6045/9212/51588/3619/4869/7153/10274/348995/79023/57122/23636/10735/8517/332/3183/10762/5465/5885/23511/10210/53371/54780/5970/4792/3190/9759/9612/6790/641/5111/2099/23279/4927/9688/79902/9656/9883/1387/10401/10521/23225/2908/2033/23512/8243/9126/142/7428/3066/3065/23314/7157/1107/1069/6256/8086/7329/5371/7376/8924/4152/672/7158/10155/9972/9063/25942/8021/9641/6117/6396/648/129401/11315/55746/8648/7421/4791/8480/10891/10062/4193/8554 98 Measles_virus R-HSA-380108 Chemokine receptors bind chemokines 45/2735 59/10654 4.997999781136357e-16 3.890488465998188e-15 1.9609377131731164e-15 729230/57007/10803/10663/7852/3579/6351/6374/1237/1230/2919/3577/3576/5196/6360/2920/2826/2921/1236/6352/6376/6348/3627/6346/6364/10563/6370/58191/1524/643/10850/1233/6372/6366/5473/4283/6363/6373/2833/6347/6357/56477/1232/1234/6387 45 Measles_virus R-HSA-2990846 SUMOylation 99/2735 188/10654 1.5471107805487041e-15 1.1974812256224434e-14 6.035710211358607e-15 1912/10054/23165/23468/7150/5905/5903/55706/7175/1487/55143/9631/3622/5468/9112/1786/6045/9212/51588/3619/4869/7153/10274/348995/79023/57122/23636/10735/8517/332/3183/10762/5465/5885/23511/10210/53371/54780/5970/4792/3190/9759/9612/6790/641/5111/2099/23279/4927/9688/79902/9656/9883/1387/10401/10521/23225/2908/2033/23512/8243/9126/142/7428/3066/3065/23314/7157/1107/1069/6256/8086/7329/5371/7376/8924/4152/672/7158/10155/9972/9063/25942/8021/9641/6117/6396/648/129401/11315/55746/8648/7421/4791/8480/10891/10062/4193/8554 99 Measles_virus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 25/2735 25/10654 1.5869896318537583e-15 1.2078754420220271e-14 6.088100576000383e-15 11065/246184/7321/991/8697/8881/7316/4085/51433/119504/51529/7324/64682/29945/10393/4751/6233/51434/701/7311/9184/25906/29882/7314/996 25 Measles_virus R-HSA-392451 G beta:gamma signalling through PI3Kgamma 25/2735 25/10654 1.5869896318537583e-15 1.2078754420220271e-14 6.088100576000383e-15 2788/5170/54331/59345/207/10681/51764/94235/55970/2792/146850/2793/23533/10000/5294/2785/2783/2784/2782/2786/208/387/2791/2790/2787 25 Measles_virus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 25/2735 25/10654 1.5869896318537583e-15 1.2078754420220271e-14 6.088100576000383e-15 1147/2308/5170/2309/842/572/207/4303/84335/1027/7249/6199/1026/55615/64223/2932/3164/10000/208/79109/2475/1385/2931/253260/4193 25 Measles_virus R-HSA-4615885 SUMOylation of DNA replication proteins 37/2735 45/10654 2.611527708937016e-15 1.9766811940572994e-14 9.963141477538136e-15 23165/7150/5905/5903/55706/7175/55143/9631/9212/51588/3619/7153/348995/79023/57122/23636/332/10762/23511/53371/6790/5111/23279/4927/9688/79902/9883/10401/23225/8086/7329/9972/8021/6396/129401/55746/8480 37 Measles_virus R-HSA-5260271 Diseases of Immune System 24/2735 24/10654 6.222685277242903e-15 4.65851302176108e-14 2.3480480539955963e-14 23643/1147/81793/4790/10333/7099/8517/4615/7098/7100/5970/7096/4792/929/114609/695/948/51135/81622/7187/7097/3551/4791/148022 24 Measles_virus R-HSA-5602358 Diseases associated with the TLR signaling cascade 24/2735 24/10654 6.222685277242903e-15 4.65851302176108e-14 2.3480480539955963e-14 23643/1147/81793/4790/10333/7099/8517/4615/7098/7100/5970/7096/4792/929/114609/695/948/51135/81622/7187/7097/3551/4791/148022 24 Measles_virus R-HSA-388841 Costimulation by the CD28 family 49/2735 70/10654 8.099923453902838e-15 6.030921267308091e-14 3.039788206956671e-14 5295/5170/5777/1326/5290/5525/5526/207/5133/941/57761/5528/3122/9020/55615/3113/6714/64223/5519/8503/29126/4067/10000/2534/5529/1445/998/942/208/5527/2885/7525/79109/2475/7409/3932/5518/5296/3127/117145/5058/5781/5062/1493/940/5879/253260/5515/5516 49 Measles_virus R-HSA-450294 MAP kinase activation 46/2735 64/10654 1.0974957605092826e-14 8.127401037284958e-14 4.0964848870218454e-14 8454/1147/3725/8945/1326/4790/6885/10392/8767/1849/5594/6500/23118/8517/5528/7316/7335/9261/5519/64127/5598/1432/23291/3656/10454/3654/7189/6233/1385/2353/7311/5518/1386/6197/5599/5600/7334/3551/6416/5608/51231/7314/5595/5515/257397/5516 46 Measles_virus R-HSA-933541 TRAF6 mediated IRF7 activation 27/2735 29/10654 2.3825593245840697e-14 1.754895846602245e-13 8.845268347069324e-14 3443/3665/3441/7186/80143/29110/57506/3449/7706/3444/23586/1387/3451/3448/2033/64135/3440/3661/7189/3439/10010/84282/3452/9641/3456/3446/3445 27 Measles_virus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 23/2735 23/10654 2.4392834506773278e-14 1.7870686242930156e-13 9.007430023328606e-14 11065/246184/7321/991/8697/8881/7316/891/983/51433/119504/51529/7324/64682/29945/10393/6233/51434/7311/25906/29882/7314/996 23 Measles_virus R-HSA-2219528 PI3K/AKT Signaling in Cancer 62/2735 101/10654 3.104124689793211e-14 2.2620483111790954e-13 1.140148822230877e-13 5295/1147/2308/5170/5290/3667/2309/5291/2065/842/3815/572/207/4303/84335/1027/8074/7249/930/941/2064/6199/2100/1950/2263/4233/1026/55615/6714/2099/64223/8503/2932/2261/5159/3164/10000/3084/2534/5728/942/208/2885/79109/2475/7409/8660/1385/3932/2931/5293/5155/1956/4254/118788/5296/5781/5156/940/5879/253260/4193 62 Measles_virus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 32/2735 38/10654 5.5780520282994306e-14 4.043349882947206e-13 2.0379850351236013e-13 23165/5903/55706/7175/9631/51588/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/7428/8086/7329/5371/9972/9063/8021/6396/129401/55746/8480/4193/8554 32 Measles_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 29/2735 33/10654 8.850706683289239e-14 6.381825345319082e-13 3.2166557253394685e-13 1147/351/4790/6885/10392/8767/23118/8517/7316/7335/5970/4792/4793/177/3146/64127/3656/10454/6288/3654/7189/6285/6233/7311/7334/3551/4791/7314/257397 29 Measles_virus R-HSA-389357 CD28 dependent PI3K/Akt signaling 22/2735 22/10654 9.559329763214652e-14 6.820980091460455e-13 3.438004563963164e-13 5295/5170/1326/5290/207/941/57761/9020/55615/64223/8503/10000/2534/942/208/79109/2475/3932/5296/117145/940/253260 22 Measles_virus R-HSA-392170 ADP signalling through P2Y purinoceptor 12 22/2735 22/10654 9.559329763214652e-14 6.820980091460455e-13 3.438004563963164e-13 2788/54331/59345/64805/2770/10681/51764/94235/55970/2792/346562/2793/2785/2783/2784/2782/2786/2771/2791/2773/2790/2787 22 Measles_virus R-HSA-418597 G alpha (z) signalling events 37/2735 48/10654 1.1683699977283012e-13 8.293610864703486e-13 4.180260259120619e-13 2788/151/54331/59345/2770/10681/51764/112/94235/114/108/150/113/55970/2778/111/107/2792/346562/152/2793/2785/2783/2784/2782/8601/2786/2771/5580/5581/196883/115/2791/109/2773/2790/2787 37 Measles_virus R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 30/2735 35/10654 1.3465662193154618e-13 9.509256291042177e-13 4.792986651497248e-13 23165/5903/55706/7175/9631/91754/140609/348995/79023/9133/57122/23636/10762/23511/891/53371/983/23279/4927/9688/79902/9883/23225/8086/9972/8021/6396/129401/55746/8480 30 Measles_virus R-HSA-4420097 VEGFA-VEGFR2 Pathway 60/2735 99/10654 1.8259985052774268e-13 1.2828810011436281e-12 6.466153951211831e-13 5295/5170/4688/5590/4893/857/5290/5335/71/558/5291/1495/1499/5747/4690/207/7422/3315/57761/5921/9047/9261/55615/10768/6714/64223/5566/1432/10000/3320/2534/9475/4846/3728/5603/998/208/1398/79109/7410/5580/2475/7409/3685/2185/387/60/5296/9564/117145/3845/5600/3265/5058/6300/801/1536/5062/5879/253260 60 Measles_virus R-HSA-877300 Interferon gamma signaling 57/2735 92/10654 1.9197527206500577e-13 1.3418679731074383e-12 6.763468231720933e-13 3135/3665/818/3460/5777/815/6737/10379/115362/960/5770/7412/3107/817/2633/9021/85363/9830/23650/3383/8638/7706/2634/3662/3122/3394/3663/3664/567/3113/6772/8651/3659/3106/3459/4939/3717/5771/3458/816/11074/3661/10346/5371/5580/3716/81603/3133/3134/3127/4940/4938/5781/4261/3105/3660/8554 57 Measles_virus R-HSA-397795 G-protein beta:gamma signalling 28/2735 32/10654 3.056916502815807e-13 2.1258759435825663e-12 1.0715133453631683e-12 2788/5170/54331/59345/207/10681/51764/94235/55970/2792/146850/2793/23533/10000/5294/2785/2783/2784/2782/998/695/2786/208/387/5058/2791/2790/2787 28 Measles_virus R-HSA-389513 CTLA4 inhibitory signaling 21/2735 21/10654 3.7451861964724177e-13 2.5913662066501075e-012 1.3061361748463083e-12 5525/5526/207/941/5528/6714/5519/4067/10000/2534/5529/942/208/5527/7525/3932/5518/5781/1493/5515/5516 21 Measles_virus R-HSA-162906 HIV Infection 110/2735 233/10654 6.663523655989114e-13 4.587450959148285e-12 2.3122303720332496e-12 5718/23165/5689/5905/8945/1173/3837/2237/5684/5903/8065/7852/5720/55706/7175/5682/9631/5700/122706/5707/5430/5690/5717/4869/9491/6500/23198/348995/143471/79023/5706/57122/5705/23636/10197/3981/10762/23511/7316/10213/5709/9978/5695/53371/292/567/3055/4836/5714/23279/4927/9688/8148/9861/79902/9150/5715/5711/23327/11168/9883/5701/5688/5437/5687/23225/5685/5683/5698/5708/5692/5686/5713/2534/5699/5710/5702/8086/5478/5719/3836/5704/6233/2968/5716/7514/163/1025/7311/9972/3932/6908/8021/7251/6396/129401/5694/2547/5062/55746/5693/1234/5721/5696/8907/5691/8480/940/7314/5879 110 Measles_virus R-HSA-451927 Interleukin-2 family signaling 34/2735 44/10654 1.0423929168155463e-12 7.1403914801864916e-12 3.598998702268412e-12 5295/5777/3635/6464/5290/1437/5291/3561/3578/6775/1439/1438/3581/6776/3560/50615/6774/6850/3718/6772/8503/3558/3717/3636/3563/2885/3716/3932/5293/2185/5296/6777/3559/59067 34 Measles_virus R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 27/2735 31/10654 1.0511007399115611e-12 7.164218973526561e-12 3.6110085644513433e-12 23165/3837/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/3836/9972/8021/6396/129401/55746/8480 27 Measles_virus R-HSA-912694 Regulation of IFNA signaling 24/2735 26/10654 1.1534781987228693e-12 7.823094714110549e-12 3.9431042124137685e-12 3443/5777/3441/5770/3455/9021/11274/3449/3444/6772/8651/3451/3448/3440/3454/3439/3716/3452/3456/6773/7297/5781/3446/3445 24 Measles_virus R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 20/2735 20/10654 1.4668990796790994e-12 9.851234015491991e-12 4.965354985910677e-12 11065/246184/7321/991/8697/8881/4085/51433/119504/51529/7324/64682/29945/10393/51434/701/9184/25906/29882/996 20 Measles_virus R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 20/2735 20/10654 1.4668990796790994e-12 9.851234015491991e-12 4.965354985910677e-12 11065/246184/7321/991/8697/8881/4085/51433/119504/51529/7324/64682/29945/10393/51434/701/9184/25906/29882/996 20 Measles_virus R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 28/2735 33/10654 1.5219253175942523e-12 1.0170915537093295e-11 5.126485280317481e-12 23165/3303/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/7514/9972/8021/6396/129401/3304/55746/8480 28 Measles_virus R-HSA-448424 Interleukin-17 signaling 47/2735 72/10654 1.6049097386043068e-12 1.0673428844116021e-11 5.3797689755974724e-12 8454/3605/1147/3725/8945/1326/4790/6885/10392/8767/1849/5594/6500/23118/8517/5528/7316/7335/9261/5519/64127/5598/1432/23291/3656/10454/3654/7189/6233/1385/2353/7311/5518/1386/6197/5599/5600/7334/3551/6416/5608/51231/7314/5595/5515/257397/5516 47 Measles_virus R-HSA-199418 Negative regulation of the PI3K/AKT network 63/2735 110/10654 1.68481420199525e-12 1.115070268953378e-11 5.620331128954406e-12 5295/23396/3643/5290/3667/90865/23035/5291/2065/5525/3815/23239/5526/207/5594/8074/930/941/2064/57761/4615/5528/2100/1950/2263/4233/6714/2099/5519/8503/2261/5159/10000/3084/2534/5728/5529/3630/942/3654/7189/208/5527/2885/7409/51135/8660/3932/5293/5518/5155/1956/4254/118788/5296/117145/5781/5156/940/5879/5595/5515/5516 63 Measles_virus R-HSA-382556 ABC-family proteins mediated transport 60/2735 103/10654 2.0902297667674825e-12 1.3767378752266592e-11 6.939224326920387e-12 5718/5689/5684/5720/1965/5682/5700/122706/5707/10956/5690/64241/5717/9491/23198/1080/143471/91319/5706/5705/10197/7316/10213/5709/335/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/8894/5683/5698/5708/5692/5686/5713/5699/6400/5710/5702/5719/5704/6233/5716/7311/51009/27248/11160/5694/5693/5721/5696/5691/7314 60 Measles_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 30/2735 37/10654 2.427622030140429e-12 1.5913120484652573e-11 8.020750701446092e-12 1017/5170/207/11200/472/639/7316/890/80196/983/55615/64223/5519/9099/10000/7157/8900/208/6233/5527/79109/2475/7311/5518/51230/7314/253260/4193/5515/5516 30 Measles_virus R-HSA-5619115 Disorders of transmembrane transporters 88/2735 176/10654 2.7113087215651504e-12 1.7688061659734552e-11 8.915381059382148e-12 5718/23165/5689/5684/5903/5720/55706/7175/5682/9631/5700/122706/5707/10956/5690/64241/5717/6528/9491/23198/1080/348995/143471/91319/79023/5706/57122/5705/23636/10197/10762/23511/7316/10213/5709/335/5695/53371/5714/23279/4927/9688/7415/9861/79902/5715/5711/9883/5701/5688/5687/23225/5685/5683/682/5698/5708/5692/5686/5713/5699/6400/5710/5702/8086/5719/5704/6233/5716/7311/51009/9972/27248/11160/8021/6396/129401/213/5694/9197/55746/5693/5721/5696/5691/8480/1356/7314 88 Measles_virus R-HSA-937041 IKK complex recruitment mediated by RIP1 23/2735 25/10654 4.177815456008954e-12 2.7126100354181356e-11 1.367247163453167e-11 23643/1147/23098/11035/7321/8737/330/7099/8517/7323/7316/7335/7322/329/929/7189/6233/7311/353376/7334/3551/7314/148022 23 Measles_virus R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 19/2735 19/10654 5.743914474369376e-12 3.694442643138988e-11 1.8621239907024018e-11 11065/246184/7321/991/8697/8881/51433/119504/51529/8556/7324/64682/29945/10393/51434/51343/25906/29882/996 19 Measles_virus R-HSA-176412 Phosphorylation of the APC/C 19/2735 19/10654 5.743914474369376e-12 3.694442643138988e-11 1.8621239907024018e-11 11065/246184/7321/8697/8881/891/983/51433/119504/51529/7324/64682/29945/10393/51434/25906/5347/29882/996 19 Measles_virus R-HSA-4085377 SUMOylation of SUMOylation proteins 28/2735 34/10654 6.506296171291434e-12 4.165245679751993e-11 2.0994246376621645e-11 23165/5903/55706/7175/9631/51588/348995/79023/57122/23636/10762/23511/10210/53371/23279/4927/9688/79902/9883/23225/8086/7329/9972/8021/6396/129401/55746/8480 28 Measles_virus R-HSA-9614085 FOXO-mediated transcription 43/2735 65/10654 7.313234852227676e-12 4.660061277931124e-11 2.3488284274474198e-11 2308/857/2309/10018/4802/7532/207/10971/4303/23410/1027/7295/2810/4287/6720/1649/7534/5934/3484/114907/4800/5443/1026/84676/1387/4088/2908/10628/10000/2033/4852/4801/3630/3066/3065/4087/56729/208/604/23411/25942/7529/10891 43 Measles_virus R-HSA-177243 Interactions of Rev with host cellular proteins 29/2735 36/10654 7.744670045897102e-12 4.889492148792179e-11 2.464469342764249e-11 23165/5905/3837/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/7514/9972/8021/6396/129401/55746/8480 29 Measles_virus R-HSA-6804757 Regulation of TP53 Degradation 29/2735 36/10654 7.744670045897102e-12 4.889492148792179e-11 2.464469342764249e-11 1017/5170/207/11200/472/7316/890/80196/983/55615/64223/5519/9099/10000/7157/8900/208/6233/5527/79109/2475/7311/5518/51230/7314/253260/4193/5515/5516 29 Measles_virus R-HSA-168276 NS1 Mediated Effects on Host Pathways 31/2735 40/10654 9.312114251862241e-12 5.85210849772994e-11 2.949660525939947e-11 23165/3837/3838/5903/402569/55706/7175/9631/348995/9636/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/3836/9972/5610/8021/6396/129401/55746/8480 31 Measles_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 187/2735 473/10654 9.536498410239137e-12 5.965754713254621e-11 3.006942060618541e-11 5295/54106/5170/5777/1173/4688/3643/5800/5590/4893/8065/6464/857/5290/2670/3667/85440/5335/71/558/5770/5291/1495/1499/2065/5340/5747/4690/526/3815/5430/10273/207/10019/1849/7422/2060/5594/10193/2322/1785/8074/3315/284217/3178/9101/10817/23118/51741/23385/4318/2064/57761/5921/58513/6778/3912/348/6696/6776/5528/9306/3688/7316/673/1950/5753/9611/5140/9047/3185/6774/2263/11059/5289/4233/102/9261/55615/4734/3915/10768/10413/6772/6714/2099/8651/26052/64223/5566/1447/5519/3673/8503/5598/1432/2261/867/5437/5159/4067/3717/4914/529/10000/9146/3320/3084/2335/2534/9475/4846/3728/8471/5771/1445/1111/5603/3630/998/83737/3914/3913/3925/6285/208/4145/1742/6233/2885/7525/1398/3187/79109/7410/7006/5580/2475/7409/8660/1385/3685/163/7311/3932/3479/1759/5518/5155/2185/387/1956/60/4254/5296/5581/9564/117145/6197/3845/5600/6777/3265/1399/5058/6300/528/801/1020/5781/1536/5062/3480/4486/5725/11140/53916/51231/7529/5156/7314/5879/253260/5595/5515/6387/5516 187 Measles_virus R-HSA-168253 Host Interactions with Influenza Factors 32/2735 42/10654 9.592332404978596e-12 5.973406997645762e-11 3.010799070653569e-11 23165/3837/3838/5903/402569/55706/7175/9631/348995/9636/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/3836/9972/5610/8021/7040/6396/129401/55746/8480 32 Measles_virus R-HSA-982772 Growth hormone receptor signaling 22/2735 24/10654 1.5078672902038668e-11 9.347412613480984e-11 4.7114119665336346e-11 5777/3667/5770/2690/9021/5594/6776/6774/6772/8651/1442/4067/3717/5618/2688/8660/1154/5617/8835/6777/2689/5595 22 Measles_virus R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 26/2735 31/10654 1.683544776809618e-11 1.0389442992023318e-10 5.236630505391699e-11 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/7514/9972/8021/6396/129401/55746/8480 26 Measles_virus R-HSA-194138 Signaling by VEGF 60/2735 107/10654 1.9328781432727566e-11 1.1874632539388686e-10 5.985216247283116e-11 5295/5170/4688/5590/4893/857/5290/5335/71/558/5291/1495/1499/5747/4690/207/7422/3315/57761/5921/9047/9261/55615/10768/6714/64223/5566/1432/10000/3320/2534/9475/4846/3728/5603/998/208/1398/79109/7410/5580/2475/7409/3685/2185/387/60/5296/9564/117145/3845/5600/3265/5058/6300/801/1536/5062/5879/253260 60 Measles_virus R-HSA-180746 Nuclear import of Rev protein 27/2735 33/10654 2.1071040102350014e-11 1.2829922195653118e-10 6.466714529656892e-11 23165/3837/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/6396/129401/55746/8480 27 Measles_virus R-HSA-180910 Vpr-mediated nuclear import of PICs 27/2735 33/10654 2.1071040102350014e-11 1.2829922195653118e-10 6.466714529656892e-11 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/11168/9883/23225/8086/3836/9972/8021/6396/129401/55746/8480 27 Measles_virus R-HSA-8964315 G beta:gamma signalling through BTK 18/2735 18/10654 2.248519482863185e-11 1.3630405714701607e-10 6.87018528532021e-11 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/695/2786/2791/2790/2787 18 Measles_virus R-HSA-202040 G-protein activation 24/2735 28/10654 4.147126705169731e-11 2.50289144761345e-10 1.2615419052127723e-10 2788/54331/59345/2770/10681/51764/94235/5173/55970/5443/2792/346562/4988/2793/2785/2783/2784/2782/2786/2771/2791/2773/2790/2787 24 Measles_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 25/2735 30/10654 5.549573085234089e-11 3.334611897706448e-10 1.680757130153999e-10 7124/1147/81858/7186/6885/8737/55072/330/23118/27005/8517/7316/7128/7132/329/9099/10616/10454/6233/7311/8717/1540/3551/7314/257397 25 Measles_virus R-HSA-165054 Rev-mediated nuclear export of HIV RNA 27/2735 34/10654 7.724933812214628e-11 4.62146695315897e-10 2.3293755829982973e-10 23165/5905/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/7514/9972/8021/6396/129401/55746/8480 27 Measles_virus R-HSA-176033 Interactions of Vpr with host cellular proteins 28/2735 36/10654 8.334663066225458e-11 4.964560174229947e-10 2.5023061654205494e-10 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/292/23279/4927/9688/79902/11168/9883/23225/8086/3836/9972/8021/6396/129401/55746/8480 28 Measles_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 19/2735 20/10654 8.700720697348471e-11 5.137925584210089e-10 2.589688193040198e-10 1147/11035/7321/8737/330/8517/7098/7323/7316/7335/7322/329/7189/6233/7311/7334/3551/7314/148022 19 Measles_virus R-HSA-8964616 G beta:gamma signalling through CDC42 19/2735 20/10654 8.700720697348471e-11 5.137925584210089e-10 2.589688193040198e-10 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/998/2786/5058/2791/2790/2787 19 Measles_virus R-HSA-9006335 Signaling by Erythropoietin 22/2735 25/10654 9.501829417292266e-11 5.586912575832791e-10 2.8159928157866395e-10 5295/4893/6464/5290/5335/5291/5336/6776/4067/23533/3717/5294/2057/2885/2056/7409/8660/5293/3845/6777/3265/1399 22 Measles_virus R-HSA-1538133 G0 and Early G1 23/2735 27/10654 1.3961906589375808e-10 8.174278644207203e-10 4.1201127857087403e-10 1017/4605/7027/7153/898/4149/286826/5934/1869/993/890/983/5933/5111/4609/5928/91750/990/3065/8900/55957/1859/132660 23 Measles_virus R-HSA-186763 Downstream signal transduction 24/2735 29/10654 1.817489115627209e-10 1.0595574844294793e-9 5.340527927666065e-10 5295/4893/5290/5335/5291/4690/5921/6778/6776/6774/6772/6714/5159/2885/1398/5155/5296/9564/3845/6777/3265/1399/5781/5156 24 Measles_virus R-HSA-912631 Regulation of signaling by CBL 20/2735 22/10654 1.9414008726383778e-10 1.1269996591163464e-9 5.680459288362068e-10 5295/5290/5291/7316/3055/6850/8503/867/4067/2534/6233/2885/7525/1398/7409/7311/5293/5296/1399/7314 20 Measles_virus R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 25/2735 31/10654 2.1658024370335905e-10 1.2467014028302602e-9 6.283796544422978e-10 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/6396/129401/55746/8480 25 Measles_virus R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 25/2735 31/10654 2.1658024370335905e-10 1.2467014028302602e-9 6.283796544422978e-10 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/6396/129401/55746/8480 25 Measles_virus R-HSA-1433557 Signaling by SCF-KIT 31/2735 43/10654 2.2396455601686928e-10 1.2838135637787067e-9 6.470854382165436e-10 5295/5777/4893/5290/3815/10019/4318/6776/9306/6774/6772/6714/8651/8503/867/4067/3717/2534/1111/2885/7525/7006/7409/3932/4254/5296/3845/6777/3265/5781/5879 31 Measles_virus R-HSA-163359 Glucagon signaling in metabolic regulation 26/2735 33/10654 2.413256371006011e-10 1.376846241966591e-9 6.939770531925344e-10 2788/54331/59345/51764/112/94235/114/108/113/55970/2778/111/107/5566/2785/2783/2784/2782/2786/5577/196883/115/2791/109/2790/2787 26 Measles_virus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 46/2735 77/10654 2.422043389152908e-10 1.376846241966591e-9 6.939770531925344e-10 1912/23165/5903/55706/7175/9631/6045/51588/10274/348995/79023/57122/23636/10735/10762/5885/23511/53371/54780/641/23279/4927/9688/79902/9656/9883/23225/8243/9126/142/1069/8086/7329/5371/8924/672/9972/9063/8021/6117/6396/648/129401/55746/8480/8554 46 Measles_virus R-HSA-977444 GABA B receptor activation 29/2735 39/10654 2.5323498500988325e-10 1.427703413430206e-9 7.196107869459969e-10 2788/54331/2770/2550/112/94235/114/108/113/55970/111/107/9568/2792/346562/2793/2785/2783/2784/2782/2786/2771/196883/3759/115/109/2773/2790/2787 29 Measles_virus R-HSA-991365 Activation of GABAB receptors 29/2735 39/10654 2.5323498500988325e-10 1.427703413430206e-9 7.196107869459969e-10 2788/54331/2770/2550/112/94235/114/108/113/55970/111/107/9568/2792/346562/2793/2785/2783/2784/2782/2786/2771/196883/3759/115/109/2773/2790/2787 29 Measles_virus R-HSA-392851 Prostacyclin signalling through prostacyclin receptor 18/2735 19/10654 3.238282412053561e-10 1.8182159444726961e-9 9.16442304705408e-10 2788/54331/59345/10681/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 18 Measles_virus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 21/2735 24/10654 3.281804319696479e-10 1.8276715113756815e-9 9.212082300902396e-10 6885/10392/8767/23118/8517/7316/7335/9261/64127/1432/3656/10454/3654/7189/6233/7311/5600/7334/5608/7314/257397 21 Measles_virus R-HSA-933542 TRAF6 mediated NF-kB activation 21/2735 24/10654 3.281804319696479e-10 1.8276715113756815e-9 9.212082300902396e-10 1147/351/7186/4790/57506/4214/7706/8517/5970/4792/4793/177/3146/23586/64135/6288/7189/6285/84282/3551/4791 21 Measles_virus R-HSA-156711 Polo-like kinase mediated events 16/2735 16/10654 3.4428423792045873e-10 1.90959273664384e-9 9.62499297148182e-10 4605/2305/1063/9133/286826/891/993/9088/5928/91750/2033/995/55957/5347/7465/132660 16 Measles_virus R-HSA-1227986 Signaling by ERBB2 34/2735 50/10654 3.788051278228061e-10 2.092592843214695e-9 1.054737537571141e-9 5295/4893/8065/6464/5290/5335/2065/10273/207/10193/9101/2064/7316/1950/5753/6714/10000/3320/3084/2534/208/4145/6233/2885/7525/5580/7311/387/1956/5581/3845/3265/11140/7314 34 Measles_virus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 56/2735 103/10654 4.5117457268664044e-10 2.4823661228140458e-9 1.2511964476112284e-9 5295/23396/3643/5290/3667/90865/5291/2065/5525/3815/5526/207/5594/8074/930/941/2064/4615/5528/2100/1950/2263/4233/6714/2099/5519/8503/2261/5159/3084/2534/5529/3630/942/3654/7189/5527/2885/7409/51135/8660/3932/5293/5518/5155/1956/4254/118788/5296/5781/5156/940/5879/5595/5515/5516 56 Measles_virus R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 23/2735 28/10654 5.9109894056724385e-010 3.226316926602088e-9 1.6261728035735456e-9 2788/54331/59345/2770/10681/51764/112/94235/150/55970/111/2792/152/2793/2785/2783/2784/2782/2786/2771/2791/2790/2787 23 Measles_virus R-HSA-69205 G1/S-Specific Transcription 23/2735 28/10654 5.9109894056724385e-010 3.226316926602088e-9 1.6261728035735456e-9 26271/8318/7027/898/286826/5934/5422/1869/1876/983/5933/5111/5928/91750/990/81620/3065/8900/7298/55957/7083/132660/6241 23 Measles_virus R-HSA-111885 Opioid Signalling 51/2735 91/10654 6.41472689514641e-10 3.4873713675994373e-9 1.757753067341706e-9 2788/818/815/3838/54331/59345/2770/817/5594/10681/51764/112/94235/114/108/113/5173/5528/55970/111/107/5443/10768/2792/346562/5566/5519/4988/2793/2785/2783/2784/2782/816/2786/2771/5577/5580/1385/5518/196883/115/801/1020/2791/109/2773/2790/5515/2787/5516 51 Measles_virus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 24/2735 30/10654 6.867616344042488e-10 3.7188278226633233e-9 1.8744149455759815e-9 11065/7319/7321/65264/7320/10477/92912/7326/7316/7317/54926/55236/3093/7322/7347/7328/7324/6233/7327/7311/55284/27338/997/7314 24 Measles_virus R-HSA-159227 Transport of the SLBP independent Mature mRNA 26/2735 34/10654 7.745736087805773e-10 4.177818283580279e-9 2.105761655035469e-9 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/10482/8086/9972/8021/6396/129401/55746/8480 26 Measles_virus R-HSA-157118 Signaling by NOTCH 103/2735 235/10654 7.846071193405088e-10 4.215340209790184e-9 2.1246739743544843e-9 8454/5718/5689/3725/5684/8841/2208/5720/79718/142678/5682/23509/892/7027/5700/5707/23462/207/4904/5690/55534/3280/5717/9491/6500/409/84441/10013/23385/5706/5705/10197/10460/10046/192670/7534/488/7316/10213/5709/9978/1950/1869/4854/9611/5695/9759/9612/102/5714/6772/4609/10320/11060/9861/10014/5715/22938/5711/5701/5688/1387/5687/4088/5685/6907/5683/5698/59/5708/5692/5686/5713/2033/408/55294/5699/6400/5710/5702/3066/3065/7157/83737/861/5719/9794/5704/6233/5716/1385/7311/1956/4343/9787/5694/3516/5693/5721/5696/10959/5691/7314 103 Measles_virus R-HSA-166658 Complement cascade 37/2735 58/10654 1.015853660261277e-9 5.4364043537419894e-9 2.7401315835994964e-9 5648/727/629/5199/1991/3004/930/27202/1378/3078/1604/1361/1401/717/966/710/81494/3075/716/1191/715/78989/1380/3426/721/975/1369/728/10878/10877/1675/719/720/4179/4153/1370/718 37 Measles_virus R-HSA-8878171 Transcriptional regulation by RUNX1 104/2735 239/10654 1.0623706932476826e-9 5.6632212052502926e-9 2.854454944790005e-9 1912/5718/6595/84661/5689/25/5684/4773/5720/1437/6597/5682/5700/122706/5707/8085/6045/9021/5690/2625/5717/5929/9491/23198/1378/4005/143471/3958/5706/6598/5705/10197/6599/192670/200845/5196/7316/10213/5709/865/5695/10398/10413/5714/23309/51412/6714/2099/122809/9861/5715/5711/5701/5688/1387/5687/3558/5685/5683/5698/5708/5692/5686/5713/10138/2033/84333/6605/50943/5699/5710/3458/5702/3065/83737/861/5719/5371/1513/23067/5704/6233/5716/7311/6688/7161/860/25942/4343/648/3276/5694/6601/3559/23466/5781/1493/5693/5721/5696/5691/7314/55170/1514 104 Measles_virus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 17/2735 18/10654 1.2016922004440985e-9 6.381078738792305e-9 3.216279410409337e-9 23643/3665/23098/29110/7099/7316/929/3661/6233/10010/7311/7187/9641/353376/5781/7314/148022 17 Measles_virus R-HSA-3700989 Transcriptional Regulation by TP53 145/2735 365/10654 1.5118925501909696e-9 7.99726947398312e-9 4.030894179741012e-9 9377/1017/23774/834/6118/2176/5170/3725/9891/64769/7862/9156/3622/7531/7027/9540/5430/9219/8445/7532/207/10971/22974/2936/9212/1027/58484/4869/3486/7249/898/5931/355/7295/7533/2810/4292/11200/545/472/192670/7534/332/580/11073/7001/5934/639/7316/1869/891/890/80196/84289/983/1026/54205/55615/6790/641/5933/6341/5111/1108/8148/64223/9150/9656/5519/6119/5928/5876/1432/1387/27154/5437/9099/51499/843/28984/10000/51755/2877/2033/995/5728/6009/7994/1111/3066/3065/7157/1107/55215/8900/8626/5371/208/10542/6233/5527/79109/2968/2475/672/1025/5932/2353/604/7311/7161/51204/5518/6834/1386/55835/6908/10419/5300/7156/4343/6117/1340/1327/5600/7159/4697/3276/5564/51230/637/1020/2744/5608/10397/57521/7248/7529/7296/7314/253260/4193/5515/1263/5516 145 Measles_virus R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 30/2735 43/10654 1.5880748618212824e-9 8.335871880058072e-9 4.20156123958363e-9 2788/54331/59345/10681/51764/112/94235/114/108/113/8766/55970/2778/111/107/2792/5566/2793/2785/2783/2784/2782/2786/5577/196883/115/2791/109/2790/2787 30 Measles_virus R-HSA-75893 TNF signaling 30/2735 43/10654 1.5880748618212824e-9 8.335871880058072e-9 4.20156123958363e-9 7124/1147/25999/81858/7186/6885/8737/55072/9530/330/23118/841/27005/8517/7316/7128/7132/329/9099/10616/10454/8567/6233/7311/8772/8717/1540/3551/7314/257397 30 Measles_virus R-HSA-5633007 Regulation of TP53 Activity 76/2735 160/10654 1.7474831125475941e-9 9.137602535077115e-9 4.605660593938214e-9 1017/23774/6118/5170/9891/64769/7862/9156/3622/9219/8445/207/22974/9212/5931/11200/545/472/580/11073/639/7316/890/80196/84289/983/55615/6790/641/1108/8148/64223/5519/6119/5928/1432/27154/9099/10000/2033/7994/1111/3066/3065/7157/1107/8900/8626/5371/208/6233/5527/79109/2475/672/5932/7311/7161/5518/6908/10419/5300/7156/6117/5600/7159/5564/51230/1020/5608/7314/253260/4193/5515/1263/5516 76 Measles_virus R-HSA-912526 Interleukin receptor SHC signaling 22/2735 27/10654 1.9080955230095295e-9 9.939508998186523e-9 5.009848561513914e-9 5295/5777/3635/6464/5290/1437/5291/3561/1439/1438/3560/3718/8503/3558/3717/3636/3563/2885/3716/5293/5296/3559 22 Measles_virus R-HSA-5218920 VEGFR2 mediated vascular permeability 23/2735 29/10654 2.1602740517512213e-9 1.1210513071587778e-8 5.650477583527914e-9 5170/857/1495/1499/207/57761/55615/64223/10000/3320/4846/3728/208/79109/7410/2475/7409/117145/5058/801/5062/5879/253260 23 Measles_virus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 26/2735 35/10654 2.27519968049694e-9 1.1762353065210595e-8 5.928623596448828e-9 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/10482/8086/9972/8021/6396/129401/55746/8480 26 Measles_virus R-HSA-622312 Inflammasomes 18/2735 20/10654 2.4552175492921966e-9 1.2645293392971088e-8 6.373655371332334e-9 834/9447/596/351/4790/10910/58484/7295/29108/5970/22861/5027/598/10628/3326/4210/114548/4791 18 Measles_virus R-HSA-114608 Platelet degranulation 64/2735 129/10654 3.843654068734064e-9 1.9722120127961302e-8 9.940615293079229e-9 928/351/5005/7018/2153/5340/51097/2316/813/3959/7422/7414/7277/334/29106/5196/10447/3827/1950/335/51706/2621/308/5216/5768/710/6694/3671/6647/7273/1191/3920/27154/197/374354/2244/81/5265/3309/9948/2335/5478/2/10487/22915/5473/948/88/2266/8407/1675/7873/7076/3479/5155/2243/7450/51368/7040/10916/213/5660/801/139322 64 Measles_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 34/2735 53/10654 3.9234149458370115e-9 2.0056262969390693e-8 1.0109034581575332e-8 596/10018/7531/7027/842/572/7532/207/10971/5594/7533/2810/841/7534/1869/8655/6774/54205/4836/22900/598/836/10000/7157/8626/208/7161/840/5599/7159/637/140735/7529/5595 34 Measles_virus R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 16/2735 17/10654 4.444884922398166e-9 2.2637518006265753e-8 1.1410074385025227e-8 23643/23098/6885/23118/7099/7316/929/3656/10454/7189/6233/7311/353376/7314/148022/257397 16 Measles_virus R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 14/2735 14/10654 5.2657729744942e-9 2.6522459467121526e-8 1.3368216220078154e-8 5862/2801/5594/5861/9133/891/26003/983/8548/8615/81876/5347/64689/5595 14 Measles_virus R-HSA-198323 AKT phosphorylates targets in the cytosol 14/2735 14/10654 5.2657729744942e-9 2.6522459467121526e-8 1.3368216220078154e-8 1147/842/572/207/84335/1027/7249/1026/2932/10000/208/2931/23608/4193 14 Measles_virus R-HSA-918233 TRAF3-dependent IRF activation pathway 14/2735 14/10654 5.2657729744942e-9 2.6522459467121526e-8 1.3368216220078154e-8 3665/80143/29110/57506/7706/23586/1387/2033/64135/3661/84282/7187/9641/3456 14 Measles_virus R-HSA-5689896 Ovarian tumor domain proteases 27/2735 38/10654 5.615571713300544e-9 2.818070786528112e-8 1.4204029473395632e-8 7321/8737/10392/8767/55611/57506/7706/8517/7316/983/2099/7415/23586/64127/7128/324/64135/5728/7157/7189/6233/7311/55593/84282/7187/387/7314 27 Measles_virus R-HSA-195721 Signaling by WNT 132/2735 331/10654 6.272860828439375e-9 3.1364304142196873e-8 1.5808669625264038e-8 2788/8454/57154/5718/5689/8945/1173/815/5684/7476/8295/857/5720/7472/54331/6885/1487/6597/5682/1499/5525/59345/4772/5700/122706/5707/1856/5526/207/8085/1454/1452/5690/5717/5929/9491/7484/6500/23198/10681/409/79577/51764/9101/94235/143471/5706/5705/10197/6657/192670/7534/64750/8452/5528/55366/7316/10213/5709/9978/5695/55970/54361/89780/51699/5216/2792/5714/9559/4609/9861/81847/5715/5881/5519/5711/2932/5701/5688/1387/2793/5687/5685/5683/5698/5708/5692/5686/5713/324/2033/2785/5699/2783/2784/5529/5710/2782/5702/3065/8313/2786/5719/208/23513/5704/6233/5527/5716/1857/7514/163/7311/5518/387/4343/25776/3845/5694/801/5693/5721/2791/5696/5691/7314/5879/4221/2790/5515/2787/5516 132 Measles_virus R-HSA-392518 Signal amplification 24/2735 32/10654 6.951344898506874e-9 3.45048641701247e-8 1.73916180527098e-8 2788/54331/59345/64805/2770/10681/51764/94235/55970/2792/346562/6714/1432/2793/2785/2783/2784/2782/2786/2771/2791/2773/2790/2787 24 Measles_virus R-HSA-5673000 RAF activation 24/2735 32/10654 6.951344898506874e-9 3.45048641701247e-8 1.73916180527098e-8 818/815/4893/5525/5526/817/5528/673/6714/5519/3717/5529/816/5894/5527/5518/3845/3265/369/801/5245/7529/5515/5516 24 Measles_virus R-HSA-114452 Activation of BH3-only proteins 23/2735 30/10654 7.001814851605599e-9 3.462991460902408e-8 1.745464770151348e-8 596/10018/7531/7027/572/7532/207/10971/7533/2810/7534/1869/8655/10000/7157/8626/208/7161/5599/7159/637/140735/7529 23 Measles_virus R-HSA-4570464 SUMOylation of RNA binding proteins 31/2735 47/10654 7.10618061607265e-9 3.489414854487287e-8 1.7587830538176412e-8 1912/23165/5903/55706/7175/9631/6045/348995/79023/57122/23636/3183/10762/23511/53371/3190/23279/4927/9688/79902/9883/23225/8086/7329/9972/8021/6396/648/129401/55746/8480 31 Measles_virus R-HSA-977606 Regulation of Complement cascade 31/2735 47/10654 7.10618061607265e-9 3.489414854487287e-8 1.7587830538176412e-8 727/629/5199/1991/930/27202/1378/3078/1604/1361/717/966/710/81494/3075/716/1191/715/1380/3426/721/975/1369/728/10878/10877/719/720/4179/1370/718 31 Measles_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 17/2735 19/10654 8.663535853973412e-9 4.208880893597013e-8 2.121418260622082e-8 5295/4893/6464/5290/5335/7316/1950/867/3320/6233/2885/7311/1956/3845/3265/11140/7314 17 Measles_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 17/2735 19/10654 8.663535853973412e-9 4.208880893597013e-8 2.121418260622082e-8 5295/4893/6464/5290/5335/7316/1950/867/3320/6233/2885/7311/1956/3845/3265/11140/7314 17 Measles_virus R-HSA-5686938 Regulation of TLR by endogenous ligand 17/2735 19/10654 8.663535853973412e-9 4.208880893597013e-8 2.121418260622082e-8 23643/653509/6271/6280/10333/7099/338/7096/6279/3146/2244/929/948/2266/2243/7097/3929 17 Measles_virus R-HSA-194315 Signaling by Rho GTPases 170/2735 455/10654 1.276139127339945e-8 6.177775987476058e-8 3.113807950660234e-8 220134/5170/5905/55839/11130/4688/25/79682/5590/5903/10403/394/54908/71/6249/55143/1495/1499/55055/25936/5525/9735/7531/5747/80776/4690/1783/1058/4659/991/1856/401541/79019/5526/4627/2316/7532/10971/348235/80152/4771/10382/9212/5594/1063/6722/613/29127/8379/1027/3619/1894/79172/1080/7533/2810/147841/7277/348995/23421/79023/55920/10381/57122/79980/64105/6280/30851/6232/7534/332/1780/23122/5528/6453/3688/5048/1781/5501/57405/10398/8655/4085/5289/5216/6279/6714/23279/55166/55114/79902/3796/54821/5881/5519/9183/1432/2017/81565/2491/1062/699/7846/999/752/22919/9475/1060/91687/995/3895/79003/5529/51143/998/4628/23028/695/83540/2/11004/354/1742/5527/2885/7410/10096/5580/701/10097/7409/1857/9055/7514/9184/9928/8826/5518/10383/54820/5347/387/57551/60/5296/5300/84643/6396/5600/23332/25909/5058/801/64946/9793/10726/1536/81930/5062/55746/2665/140735/5500/7529/5879/4221/5595/5515/1778/5516 170 Measles_virus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 15/2735 16/10654 1.6381854120815162e-8 7.902514135745343e-8 3.983134285861655e-8 23643/6885/23118/7099/7316/929/3656/10454/7189/6233/7311/353376/7314/148022/257397 15 Measles_virus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 19/2735 23/10654 1.6760020194711436e-8 8.056571111141988e-8 4.060784209688163e-8 6885/10392/8767/23118/8517/7316/7335/64127/3656/10454/3654/7189/6233/7311/5599/7334/6416/7314/257397 19 Measles_virus R-HSA-5663205 Infectious disease 147/2735 383/10654 1.7424507116926907e-8 8.346704458108342e-8 4.2070212251395104e-8 928/5718/23165/3303/5689/5905/8945/1173/3837/3838/2237/5684/5903/9349/8065/7852/5720/402569/55706/7175/5682/6132/9631/1499/6217/5700/122706/5707/5430/6176/5690/2060/5717/4869/821/9491/6500/23198/84168/811/348995/9636/143471/79023/5706/57122/5705/23636/10197/6232/3981/10762/23511/7316/10213/5709/9978/5695/53371/5611/292/567/4233/3055/4836/5714/6714/23279/4927/9688/8148/9861/79902/6130/9150/5715/5711/23327/11168/9883/5701/867/5688/5437/5687/23225/999/5685/5683/5698/5708/9146/3320/5692/5686/5713/2534/5699/5710/5702/8086/5478/5719/3836/5704/6233/2885/3326/6844/2968/5716/7514/163/1025/7311/9972/3932/5610/6908/3921/6188/8021/7040/7251/6396/129401/5694/3304/2547/801/6416/5608/5062/55746/6168/5693/1234/5721/5696/8907/5691/8480/7296/940/7314/5879/6230 147 Measles_virus R-HSA-5357905 Regulation of TNFR1 signaling 24/2735 33/10654 1.9271665185048626e-8 9.199366307845512e-8 4.636791623470346e-8 7124/1147/25999/81858/7186/8737/55072/330/841/27005/8517/7316/7128/7132/329/9099/10616/8567/6233/7311/8717/1540/3551/7314 24 Measles_virus R-HSA-8854691 Interleukin-20 family signaling 20/2735 25/10654 1.9395304092733505e-8 9.226238405223925e-8 4.650336069017975e-8 6775/50616/11009/53833/6776/6774/3718/6772/3717/163702/58985/3716/282618/53832/3588/6777/55801/6773/7297/5781 20 Measles_virus R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13/2735 13/10654 2.05852645927968e-8 9.758412627035161e-8 4.91856986810224e-8 7531/7532/10971/7533/2810/11200/7534/891/983/995/1111/7465/7529 13 Measles_virus R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 64/2735 134/10654 2.5506562855155597e-8 1.2049652107435576e-7 6.07343202649077e-8 928/351/5005/7018/2153/5340/51097/2316/813/3959/7422/7414/7277/334/29106/5196/10447/3827/1950/335/51706/2621/308/5216/5768/710/6694/3671/6647/7273/1191/3920/27154/197/374354/2244/81/5265/3309/9948/2335/5478/2/10487/22915/5473/948/88/2266/8407/1675/7873/7076/3479/5155/2243/7450/51368/7040/10916/213/5660/801/139322 64 Measles_virus R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 16/2735 18/10654 3.039042669803059e-8 1.430752047295598e-7 7.211474014797636e-8 5295/8805/11052/26127/5290/613/9208/6776/6774/6772/399687/11064/2885/6777/7750/1523 16 Measles_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 30/2735 47/10654 3.86054231232174e-8 1.8112818383153368e-7 9.129472807797624e-8 8454/8841/79718/892/23462/55534/3280/6500/84441/10013/10046/7316/9978/9611/9759/9612/4609/10014/22938/1387/6907/2033/55294/3066/3065/9794/6233/7311/3516/7314 30 Measles_virus R-HSA-418217 G beta:gamma signalling through PLC beta 17/2735 20/10654 4.384400624716696e-8 2.0500439781098543e-7 1.0332914711026234e-7 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Measles_virus R-HSA-2980766 Nuclear Envelope Breakdown 32/2735 52/10654 4.887862558099866e-8 2.2776774505431348e-7 1.148026436846943e-7 23165/5903/55706/7175/9631/91754/140609/348995/79023/9133/57122/23636/10762/23511/891/53371/983/23279/4927/9688/79902/9883/23225/8086/9972/5347/8021/6396/129401/55746/7112/8480 32 Measles_virus R-HSA-447115 Interleukin-12 family signaling 34/2735 57/10654 5.660027758290183e-8 2.628555264019509e-7 1.324880717016364e-7 10148/3592/3593/6775/9446/3595/821/9987/4478/3313/3185/6774/6772/6647/149233/3717/5306/9466/3458/3181/998/5478/3716/3594/2939/302/51561/246778/7297/5062/5721/3586/5034/3572 34 Measles_virus R-HSA-6804758 Regulation of TP53 Activity through Acetylation 22/2735 30/10654 5.99500328876095e-8 2.764537786759099e-7 1.3934205056580628e-7 23774/64769/7862/3622/9219/207/5931/84289/1108/5928/27154/10000/2033/7994/3066/3065/7157/1107/5371/208/5300/5608 22 Measles_virus R-HSA-1170546 Prolactin receptor signaling 14/2735 15/10654 6.013374163899354e-8 2.764537786759099e-7 1.3934205056580628e-7 8454/8945/2690/6500/6776/9978/1442/3717/5618/2688/5617/6777/2689/5781 14 Measles_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 14/2735 15/10654 6.013374163899354e-8 2.764537786759099e-7 1.3934205056580628e-7 54106/3665/4615/7316/7335/3654/7189/6233/51311/51135/7311/7334/51284/7314 14 Measles_virus R-HSA-3371571 HSF1-dependent transactivation 19/2735 24/10654 6.098872959171378e-8 2.7944668742691596e-7 1.4085057775801526e-7 818/3303/815/817/84335/3337/3305/64223/1387/3320/2033/816/3326/2475/3306/3304/3312/3297/57521 19 Measles_virus R-HSA-8984722 Interleukin-35 Signalling 12/2735 12/10654 8.045111487203224e-8 3.6375586592305003e-7 1.8334525397273975e-7 10148/3592/6775/3595/821/6774/6772/3717/9466/3716/7297/3572 12 Measles_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 12/2735 12/10654 8.045111487203224e-8 3.6375586592305003e-7 1.8334525397273975e-7 3665/29110/7098/7316/3661/6233/10010/7311/7187/9641/7314/148022 12 Measles_virus R-HSA-9020558 Interleukin-2 signaling 12/2735 12/10654 8.045111487203224e-8 3.6375586592305003e-7 1.8334525397273975e-7 6464/3561/6776/3560/6850/3718/3558/3716/3932/2185/6777/3559 12 Measles_virus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12/2735 12/10654 8.045111487203224e-8 3.6375586592305003e-7 1.8334525397273975e-7 1147/8737/57506/841/7706/8517/23586/843/64135/84282/8772/3551 12 Measles_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 40/2735 73/10654 1.038565195629527e-7 4.680376046093592e-7 2.3590677573856291e-7 57154/5590/892/7027/7321/51377/6497/10273/4738/64750/7323/54778/7316/9611/5501/9612/6667/5933/4609/22938/23327/867/23645/4088/142/3065/9958/9040/4087/6233/7514/7048/1025/7311/9110/387/7040/5500/7314/4221 40 Measles_virus R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 16/2735 19/10654 1.4626717786633582e-7 6.570033891045249e-7 3.3115191951791647e-7 7027/7153/4149/286826/5934/1869/993/5933/5111/4609/5928/91750/990/3065/55957/132660 16 Measles_virus R-HSA-500657 Presynaptic function of Kainate receptors 17/2735 21/10654 1.7478655074242798e-7 7.825410931932233e-7 3.94427166450061e-7 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Measles_virus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 29/2735 47/10654 1.9191104907262545e-7 8.481230233209576e-7 4.274826763722998e-7 818/815/4893/71/817/5594/409/7414/673/6714/3717/2244/2335/408/1445/816/5894/2266/8826/2243/7450/60/3845/3265/369/801/5245/7529/5595 29 Measles_virus R-HSA-6802949 Signaling by RAS mutants 29/2735 47/10654 1.9191104907262545e-7 8.481230233209576e-7 4.274826763722998e-7 818/815/4893/71/817/5594/409/7414/673/6714/3717/2244/2335/408/1445/816/5894/2266/8826/2243/7450/60/3845/3265/369/801/5245/7529/5595 29 Measles_virus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 29/2735 47/10654 1.9191104907262545e-7 8.481230233209576e-7 4.274826763722998e-7 818/815/4893/71/817/5594/409/7414/673/6714/3717/2244/2335/408/1445/816/5894/2266/8826/2243/7450/60/3845/3265/369/801/5245/7529/5595 29 Measles_virus R-HSA-9649948 Signaling downstream of RAS mutants 29/2735 47/10654 1.9191104907262545e-7 8.481230233209576e-7 4.274826763722998e-7 818/815/4893/71/817/5594/409/7414/673/6714/3717/2244/2335/408/1445/816/5894/2266/8826/2243/7450/60/3845/3265/369/801/5245/7529/5595 29 Measles_virus R-HSA-418592 ADP signalling through P2Y purinoceptor 1 19/2735 25/10654 1.927012436718179e-7 8.488768611909663e-7 4.278626361438908e-7 2788/54331/59345/10681/51764/94235/55970/2792/6714/1432/2793/2785/2783/2784/2782/2786/2791/2790/2787 19 Measles_virus R-HSA-170670 Adenylate cyclase inhibitory pathway 13/2735 14/10654 2.1973865563073046e-7 9.617953936552738e-7 4.8477739395917e-7 2770/112/114/108/113/111/107/346562/2771/196883/115/109/2773 13 Measles_virus R-HSA-877312 Regulation of IFNG signaling 13/2735 14/10654 2.1973865563073046e-7 9.617953936552738e-7 4.8477739395917e-7 3460/5777/5770/9021/6772/8651/3459/3717/5771/3458/3716/5781/8554 13 Measles_virus R-HSA-6802952 Signaling by BRAF and RAF fusions 37/2735 67/10654 2.3842802632737727e-7 1.0402751467149901e-6 5.243338426777053e-7 818/815/8805/4893/71/10018/10142/55750/817/5594/409/7414/10533/55109/23164/673/8546/6714/3717/2244/2335/408/1445/816/5894/2266/8826/2243/7450/60/3845/3265/369/801/9715/7529/5595 37 Measles_virus R-HSA-187037 Signaling by NTRK1 (TRKA) 42/2735 80/10654 2.48152577477829e-7 1.0792667655384942e-6 5.439869367600863e-7 5295/1173/4893/6464/5290/3667/5335/5291/1849/5594/1785/5528/673/6774/9261/6714/26052/5519/5598/1432/4914/5603/2885/1398/8660/1385/163/1759/5518/387/5296/6197/3845/5600/3265/1399/6300/51231/7529/5595/5515/5516 42 Measles_virus R-HSA-168325 Viral Messenger RNA Synthesis 27/2735 43/10654 3.0462402794870515e-7 1.3206801211700191e-6 6.656674294948386e-7 23165/5903/55706/7175/9631/5430/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/5437/23225/8086/9972/8021/6396/129401/55746/8480 27 Measles_virus R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 32/2735 55/10654 3.112152188623091e-7 1.3415428856098114e-6 6.76182968083009e-7 3303/11258/1783/10382/10294/55860/7277/10381/3337/1780/1781/3305/8655/1639/832/2289/10121/7846/2908/3320/51143/3301/10540/10963/3326/3306/10383/3304/3312/55466/140735/1778 32 Measles_virus R-HSA-1059683 Interleukin-6 signaling 11/2735 11/10654 3.143323111538317e-7 1.3415428856098114e-6 6.76182968083009e-7 9021/6774/6772/867/3717/3716/3570/7297/5781/3569/3572 11 Measles_virus R-HSA-5603041 IRAK4 deficiency (TLR2/4) 11/2735 11/10654 3.143323111538317e-7 1.3415428856098114e-6 6.76182968083009e-7 23643/10333/7099/4615/7096/929/114609/695/948/51135/7097 11 Measles_virus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 11/2735 11/10654 3.143323111538317e-7 1.3415428856098114e-6 6.76182968083009e-7 6885/23118/7098/7316/10454/7189/6233/7311/7314/148022/257397 11 Measles_virus R-HSA-9614399 Regulation of localization of FOXO transcription factors 11/2735 11/10654 3.143323111538317e-7 1.3415428856098114e-6 6.76182968083009e-7 2308/2309/7532/207/10971/4303/2810/7534/10000/208/7529 11 Measles_virus R-HSA-1295596 Spry regulation of FGF signaling 14/2735 16/10654 3.663969542662405e-7 1.5540675769187292e-6 7.833025973558864e-7 5594/7316/673/6714/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 14 Measles_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 14/2735 16/10654 3.663969542662405e-7 1.5540675769187292e-6 7.833025973558864e-7 8454/1147/8945/1326/4790/6500/8517/7316/23291/6233/7311/3551/6416/7314 14 Measles_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 22/2735 32/10654 3.7879447512921064e-7 1.596764402852365e-6 8.048232410842498e-7 57154/51377/10273/4738/64750/7316/5501/23327/867/23645/4088/9958/9040/4087/6233/7514/7048/7311/9110/7040/5500/7314 22 Measles_virus R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 22/2735 32/10654 3.7879447512921064e-7 1.596764402852365e-6 8.048232410842498e-7 2788/54331/59345/5594/10681/409/51764/94235/55970/2792/6714/2793/408/2785/2783/2784/2782/2786/2791/5595/2790/2787 22 Measles_virus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 26/2735 41/10654 3.8075511037453295e-7 1.6001058319420557e-6 8.065074343096338e-7 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/10482/8086/9972/8021/6396/129401/55746/8480 26 Measles_virus R-HSA-1236394 Signaling by ERBB4 33/2735 58/10654 4.1890346457737216e-7 1.728607670093373e-6 8.712767050182503e-7 5295/4893/6464/5290/2670/2065/23118/51741/23385/348/6776/7316/1950/9611/11059/4734/10413/6714/2099/1447/3084/83737/3925/6285/1742/6233/2885/7311/1956/3845/3265/7314/6387 33 Measles_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 33/2735 58/10654 4.1890346457737216e-7 1.728607670093373e-6 8.712767050182503e-7 8454/8841/79718/142678/892/23462/55534/3280/6500/84441/10013/23385/10046/7316/9978/9611/9759/9612/102/4609/10014/22938/1387/6907/2033/55294/3066/3065/9794/6233/7311/3516/7314 33 Measles_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 33/2735 58/10654 4.1890346457737216e-7 1.728607670093373e-6 8.712767050182503e-7 8454/8841/79718/142678/892/23462/55534/3280/6500/84441/10013/23385/10046/7316/9978/9611/9759/9612/102/4609/10014/22938/1387/6907/2033/55294/3066/3065/9794/6233/7311/3516/7314 33 Measles_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 33/2735 58/10654 4.1890346457737216e-7 1.728607670093373e-6 8.712767050182503e-7 8454/8841/79718/142678/892/23462/55534/3280/6500/84441/10013/23385/10046/7316/9978/9611/9759/9612/102/4609/10014/22938/1387/6907/2033/55294/3066/3065/9794/6233/7311/3516/7314 33 Measles_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 33/2735 58/10654 4.1890346457737216e-7 1.728607670093373e-6 8.712767050182503e-7 8454/8841/79718/142678/892/23462/55534/3280/6500/84441/10013/23385/10046/7316/9978/9611/9759/9612/102/4609/10014/22938/1387/6907/2033/55294/3066/3065/9794/6233/7311/3516/7314 33 Measles_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 33/2735 58/10654 4.1890346457737216e-7 1.728607670093373e-6 8.712767050182503e-7 8454/8841/79718/142678/892/23462/55534/3280/6500/84441/10013/23385/10046/7316/9978/9611/9759/9612/102/4609/10014/22938/1387/6907/2033/55294/3066/3065/9794/6233/7311/3516/7314 33 Measles_virus R-HSA-2424491 DAP12 signaling 21/2735 30/10654 4.3722071836301196e-7 1.7987759284003797e-6 9.066438793935067e-7 5295/4893/6464/5290/5335/7305/5291/5336/54209/567/6850/2534/695/2885/7410/3133/3932/5296/3845/3265/5879 21 Measles_virus R-HSA-4551638 SUMOylation of chromatin organization proteins 38/2735 71/10654 4.837457104175881e-7 1.978303353051032e-6 9.971317707272201e-7 1912/23165/23468/5903/55706/7175/9631/6045/348995/79023/57122/23636/10762/23511/53371/9759/23279/4927/9688/79902/9883/23225/23512/3066/3065/23314/1107/8086/7329/9972/9063/8021/6396/648/129401/55746/8480/8554 38 Measles_virus R-HSA-6802957 Oncogenic MAPK signaling 38/2735 71/10654 4.837457104175881e-7 1.978303353051032e-6 9.971317707272201e-7 818/815/8805/4893/71/10018/10142/55750/817/5594/409/7414/10533/55109/23164/673/8546/6714/3717/2244/2335/408/1445/816/5894/2266/8826/2243/7450/60/3845/3265/369/801/9715/5245/7529/5595 38 Measles_virus R-HSA-390466 Chaperonin-mediated protein folding 47/2735 95/10654 4.919196238123012e-7 2.005743704234681e-6 1.0109626354037266e-6 2788/10694/26224/8841/54331/59345/2770/8237/10382/10681/5203/898/51764/7277/94235/10381/10517/10576/55970/6774/2792/26272/346562/11328/2793/26270/7846/2785/55294/2783/26190/2784/10238/2782/7157/2786/2771/6468/10383/60/54461/26234/2791/84261/2773/2790/2787 47 Measles_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 19/2735 26/10654 5.429025540745746e-7 2.207051926059843e-6 1.1124287848599747e-6 57154/51377/10273/64750/7316/5501/23327/23645/4088/9958/4087/6233/7514/7048/7311/9110/7040/5500/7314 19 Measles_virus R-HSA-8943724 Regulation of PTEN gene transcription 34/2735 61/10654 5.451820094522994e-7 2.20976139925932e-6 1.1137944509520661e-6 1912/3725/8841/5468/1822/23186/5978/9112/9219/6045/5594/5931/1108/64223/10014/1958/5928/23512/6009/6615/3066/3065/7157/1107/23028/10542/2475/57504/1386/8726/648/23466/57521/5595 34 Measles_virus R-HSA-391251 Protein folding 49/2735 101/10654 5.999069813592164e-7 2.4244028450210217e-6 1.2219809960305726e-6 2788/10694/26224/8841/54331/59345/2770/8237/10382/10681/5203/898/51764/7277/94235/10381/10517/10576/55970/6774/2792/6902/26272/346562/11328/2793/26270/7846/2785/55294/2783/26190/2784/10238/2782/7157/2786/2771/6468/10383/60/54461/26234/2791/84261/6904/2773/2790/2787 49 Measles_virus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 26/2735 42/10654 7.557592024635724e-7 3.0452650216914533e-6 1.5349165226504753e-6 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/10482/8086/9972/8021/6396/129401/55746/8480 26 Measles_virus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 12/2735 13/10654 7.988413182228554e-7 3.2000368595476956e-6 1.6129267613240784e-6 2065/207/10193/9101/2064/7316/10000/3084/208/6233/7311/7314 12 Measles_virus R-HSA-1679131 Trafficking and processing of endosomal TLR 12/2735 13/10654 7.988413182228554e-7 3.2000368595476956e-6 1.6129267613240784e-6 54106/10695/7184/7098/5641/1513/51311/1520/81622/1508/51284/1514 12 Measles_virus R-HSA-445717 Aquaporin-mediated transport 30/2735 52/10654 9.35333392630416e-7 3.7358797314975797e-6 1.8830096841048114e-6 2788/54331/59345/10681/51764/112/94235/114/108/113/8766/55970/2778/111/107/2792/5566/2793/2785/2783/2784/2782/2786/5577/196883/115/2791/109/2790/2787 30 Measles_virus R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 20/2735 29/10654 1.206630584100511e-6 4.805476454121221e-6 2.4221225923192635e-6 2308/2309/4303/23410/4287/6720/3484/114907/5443/84676/4088/2908/4852/3630/3066/3065/4087/56729/25942/10891 20 Measles_virus R-HSA-381183 ATF6 (ATF6-alpha) activates chaperone genes 10/2735 10/10654 1.2277993100628905e-6 4.810960104219294e-6 2.4248865373552495e-6 4802/7184/7494/811/1649/468/4800/3309/4801/22926 10 Measles_virus R-HSA-5602498 MyD88 deficiency (TLR2/4) 10/2735 10/10654 1.2277993100628905e-6 4.810960104219294e-6 2.4248865373552495e-6 23643/10333/7099/4615/7096/929/114609/695/948/7097 10 Measles_virus R-HSA-9020958 Interleukin-21 signaling 10/2735 10/10654 1.2277993100628905e-6 4.810960104219294e-6 2.4248865373552495e-6 3561/6775/6776/50615/6774/3718/6772/3716/6777/59067 10 Measles_virus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 10/2735 10/10654 1.2277993100628905e-6 4.810960104219294e-6 2.4248865373552495e-6 6885/23118/7316/3656/10454/7189/6233/7311/7314/257397 10 Measles_virus R-HSA-111447 Activation of BAD and translocation to mitochondria 13/2735 15/10654 1.2571705965770127e-6 4.810960104219294e-6 2.4248865373552495e-6 596/7531/572/7532/207/10971/7533/2810/7534/10000/208/637/7529 13 Measles_virus R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 13/2735 15/10654 1.2571705965770127e-6 4.810960104219294e-6 2.4248865373552495e-6 1499/5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 13 Measles_virus R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 13/2735 15/10654 1.2571705965770127e-6 4.810960104219294e-6 2.4248865373552495e-6 1499/5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 13 Measles_virus R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 13/2735 15/10654 1.2571705965770127e-6 4.810960104219294e-6 2.4248865373552495e-6 1499/5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 13 Measles_virus R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 13/2735 15/10654 1.2571705965770127e-6 4.810960104219294e-6 2.4248865373552495e-6 1499/5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 13 Measles_virus R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 13/2735 15/10654 1.2571705965770127e-6 4.810960104219294e-6 2.4248865373552495e-6 1499/5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 13 Measles_virus R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 13/2735 15/10654 1.2571705965770127e-6 4.810960104219294e-6 2.4248865373552495e-6 1499/5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 13 Measles_virus R-HSA-5637810 Constitutive Signaling by EGFRvIII 13/2735 15/10654 1.2571705965770127e-6 4.810960104219294e-6 2.4248865373552495e-6 5295/4893/6464/5290/5335/1950/867/3320/2885/1956/3845/3265/11140 13 Measles_virus R-HSA-5637812 Signaling by EGFRvIII in Cancer 13/2735 15/10654 1.2571705965770127e-6 4.810960104219294e-6 2.4248865373552495e-6 5295/4893/6464/5290/5335/1950/867/3320/2885/1956/3845/3265/11140 13 Measles_virus R-HSA-844456 The NLRP3 inflammasome 13/2735 15/10654 1.2571705965770127e-6 4.810960104219294e-6 2.4248865373552495e-6 834/351/4790/10910/7295/29108/5970/5027/10628/3326/4210/114548/4791 13 Measles_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 34/2735 63/10654 1.4936028824326425e-6 5.699821584770809e-6 2.8729027734227044e-6 1147/3665/11035/6737/4790/1499/8737/29110/8517/6778/4615/7098/9208/5591/7316/51428/5970/4792/4793/3428/1387/5437/2033/22954/1660/3661/6233/7311/171568/3551/2547/4791/7314/148022 34 Measles_virus R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 18/2735 25/10654 1.5627011436611241e-6 5.946946018932611e-6 2.9974618428119806e-6 1017/994/2305/9133/891/993/890/983/5519/9088/995/8900/7514/5518/5347/7465/5515/5516 18 Measles_virus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 14/2735 17/10654 1.5820068330002981e-6 6.003737842688112e-6 3.0260868419542073e-6 1147/11035/4790/8737/8517/4615/7098/5970/4792/4793/1660/3551/4791/148022 14 Measles_virus R-HSA-191859 snRNP Assembly 30/2735 53/10654 1.6281730013208831e-6 6.144895349337768e-6 3.097234997438014e-6 23165/5903/6632/55706/7175/9631/8487/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/1207/8086/9972/10419/8021/6396/129401/55746/8480/6628 30 Measles_virus R-HSA-194441 Metabolism of non-coding RNA 30/2735 53/10654 1.6281730013208831e-6 6.144895349337768e-6 3.097234997438014e-6 23165/5903/6632/55706/7175/9631/8487/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/1207/8086/9972/10419/8021/6396/129401/55746/8480/6628 30 Measles_virus R-HSA-166520 Signaling by NTRKs 48/2735 101/10654 1.6586571770445087e-6 6.242748166348838e-6 3.1465561253360257e-6 5295/1173/5800/4893/6464/5290/3667/5335/5291/1849/5594/1785/10817/5528/673/6774/9261/6714/26052/5519/5598/1432/4914/2534/5603/2885/1398/8660/1385/163/1759/5518/387/5296/6197/3845/5600/3265/1399/6300/1020/5781/51231/7529/5879/5595/5515/5516 48 Measles_virus R-HSA-428930 Thromboxane signalling through TP receptor 17/2735 23/10654 1.7014854602406123e-6 6.38639748090312e-6 3.2189602362446767e-6 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Measles_virus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 16/2735 21/10654 1.7757144678648825e-6 6.64680005730844e-6 3.3502119382207737e-6 1147/11035/4790/8737/29110/8517/4615/7098/5970/4792/4793/1660/3661/3551/4791/148022 16 Measles_virus R-HSA-8939211 ESR-mediated signaling 89/2735 223/10654 1.7811343451957626e-6 6.648921125117696e-6 3.351281028103887e-6 5295/2788/5170/3725/3838/596/5590/4893/6464/857/5290/54331/2309/5747/59345/5430/2770/207/1903/2625/5594/6722/1027/3315/10681/10274/51764/94235/4318/10735/5481/192670/200845/5885/2100/1950/865/55970/5469/6667/2792/346562/2289/6714/2099/4609/8503/1387/5437/2793/10000/3320/2033/8243/2785/4846/9126/2783/2784/2782/3065/861/23028/2786/2771/208/3326/7514/1385/1025/2353/1386/6908/1956/5296/4343/3845/3276/3265/801/8648/3480/2791/2773/5595/2790/2787/7528/6387 89 Measles_virus R-HSA-9006931 Signaling by Nuclear Receptors 113/2735 299/10654 1.9162789535378007e-6 7.133973278116269e-6 3.595763711443928e-6 5295/2788/5170/3725/3838/596/5590/4893/6464/8841/857/5290/54331/1374/79718/2309/5747/59345/5160/5430/2770/207/1903/2625/64241/5594/6722/1027/3315/10681/10274/1737/51764/94235/4318/10735/126/5481/6720/192670/200845/348/5885/2100/1950/9611/865/55970/5469/2874/2194/9612/6667/2792/346562/2289/6714/2099/4609/8503/124/1387/5437/2793/2171/5467/6907/10000/3320/2033/5162/221656/8243/2785/4846/9126/2783/2784/2782/3065/861/23028/6256/2786/2771/7376/208/3326/7514/1385/1025/2353/1738/1386/6908/1956/5296/4343/3845/3276/3265/801/29116/8648/3480/2791/2773/10062/5595/2790/2787/7528/6387 113 Measles_virus R-HSA-201681 TCF dependent signaling in response to WNT 92/2735 233/10654 2.063876501466471e-6 7.6626309133037e-6 3.862225031984039e-6 5718/5689/8945/5684/8295/857/5720/1487/6597/5682/1499/5525/5700/122706/5707/1856/5526/207/8085/1454/1452/5690/5717/5929/9491/23198/79577/9101/143471/5706/5705/10197/6657/7534/64750/8452/5528/55366/7316/10213/5709/9978/5695/54361/89780/5714/4609/9861/81847/5715/5519/5711/2932/5701/5688/1387/5687/5685/5683/5698/5708/5692/5686/5713/324/2033/5699/5529/5710/5702/3065/8313/5719/208/5704/6233/5527/5716/1857/7514/7311/5518/25776/5694/5693/5721/5696/5691/7314/4221/5515/5516 92 Measles_virus R-HSA-2871796 FCERI mediated MAPK activation 21/2735 32/10654 2.264764837820292e-6 8.385750885983242e-6 4.226701944836732e-6 3725/4893/6464/5335/5336/5594/4214/6850/4067/2885/7410/7409/2353/3845/5599/3265/5058/6416/5062/5879/5595 21 Measles_virus R-HSA-381033 ATF6 (ATF6-alpha) activates chaperones 11/2735 12/10654 2.887025470253637e-6 1.0603820091816308e-5 5.344683811165192e-6 8720/4802/7184/7494/811/1649/468/4800/3309/4801/22926 11 Measles_virus R-HSA-389359 CD28 dependent Vav1 pathway 11/2735 12/10654 2.887025470253637e-6 1.0603820091816308e-5 5.344683811165192e-6 941/2534/998/942/2885/7409/3932/5058/5062/940/5879 11 Measles_virus R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 11/2735 12/10654 2.887025470253637e-6 1.0603820091816308e-5 5.344683811165192e-6 5295/5290/5291/4067/23533/3717/5294/2057/2056/8660/5293 11 Measles_virus R-HSA-114604 GPVI-mediated activation cascade 22/2735 35/10654 3.7686447321950283e-6 1.3804928564457723e-5 6.958150701716685e-6 5295/5170/5777/5590/5290/5291/5336/6850/8503/146850/4067/23533/5294/2534/998/7410/7409/3932/387/5296/5781/5879 22 Measles_virus R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 12/2735 14/10654 4.2734572937755965e-6 1.536649998024296e-5 7.745235487544664e-6 5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 12 Measles_virus R-HSA-4839744 truncated APC mutants destabilize the destruction complex 12/2735 14/10654 4.2734572937755965e-6 1.536649998024296e-5 7.745235487544664e-6 5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 12 Measles_virus R-HSA-4839748 AMER1 mutants destabilize the destruction complex 12/2735 14/10654 4.2734572937755965e-6 1.536649998024296e-5 7.745235487544664e-6 5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 12 Measles_virus R-HSA-5467337 APC truncation mutants have impaired AXIN binding 12/2735 14/10654 4.2734572937755965e-6 1.536649998024296e-5 7.745235487544664e-6 5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 12 Measles_virus R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 12/2735 14/10654 4.2734572937755965e-6 1.536649998024296e-5 7.745235487544664e-6 5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 12 Measles_virus R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 12/2735 14/10654 4.2734572937755965e-6 1.536649998024296e-5 7.745235487544664e-6 5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 12 Measles_virus R-HSA-9027284 Erythropoietin activates RAS 12/2735 14/10654 4.2734572937755965e-6 1.536649998024296e-5 7.745235487544664e-6 4893/6464/4067/3717/2057/2885/2056/7409/8660/3845/3265/1399 12 Measles_virus R-HSA-5654741 Signaling by FGFR3 24/2735 40/10654 4.459858488332107e-6 1.5953018613616153e-5 8.040860707285591e-6 5295/4893/6464/5290/5335/5594/8074/10817/7316/673/6714/2261/867/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 24 Measles_virus R-HSA-5675221 Negative regulation of MAPK pathway 24/2735 40/10654 4.459858488332107e-6 1.5953018613616153e-5 8.040860707285591e-6 4893/1844/5525/5526/1849/5594/5528/7316/673/5519/5529/5894/6233/5527/7311/5518/3845/3265/369/7529/7314/5595/5515/5516 24 Measles_virus R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs 57/2735 130/10654 4.632483876111209e-6 1.6527351328834263e-5 8.330343812305243e-6 5718/5689/25/5684/5720/5682/5700/122706/5707/5690/2625/5717/9491/23198/4005/143471/5706/5705/10197/7316/10213/5709/865/5695/10413/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/83737/861/5719/5704/6233/5716/7311/6688/7161/5694/5693/5721/5696/5691/7314 57 Measles_virus R-HSA-70171 Glycolysis 36/2735 71/10654 5.1140460317880755e-6 1.806842759577877e-5 9.107098350235014e-6 23165/7167/5903/2597/55706/7175/9631/348995/79023/57122/23636/5214/10762/23511/5528/53371/23279/4927/9688/79902/5566/5519/9883/2023/23225/5208/8086/9972/5518/8021/6396/129401/55746/8480/5515/5516 36 Measles_virus R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 13/2735 16/10654 5.117189713257053e-6 1.806842759577877e-5 9.107098350235014e-6 4605/7027/286826/5934/1869/890/983/5933/5928/91750/3065/55957/132660 13 Measles_virus R-HSA-1433559 Regulation of KIT signaling 13/2735 16/10654 5.117189713257053e-6 1.806842759577877e-5 9.107098350235014e-6 5777/3815/10019/9306/6714/8651/867/4067/2534/2885/7525/3932/4254 13 Measles_virus R-HSA-193639 p75NTR signals via NF-kB 13/2735 16/10654 5.117189713257053e-6 1.806842759577877e-5 9.107098350235014e-6 4790/8767/8878/4615/7316/5970/4792/3654/7189/6233/7311/3551/7314 13 Measles_virus R-HSA-5213460 RIPK1-mediated regulated necrosis 15/2735 20/10654 5.3246622370825325e-6 1.870458273026428e-5 9.42774204460497e-6 11035/7186/8737/355/330/841/7316/329/197259/6233/7311/8772/8717/8743/7314 15 Measles_virus R-HSA-5218859 Regulated Necrosis 15/2735 20/10654 5.3246622370825325e-6 1.870458273026428e-5 9.42774204460497e-6 11035/7186/8737/355/330/841/7316/329/197259/6233/7311/8772/8717/8743/7314 15 Measles_virus R-HSA-5655302 Signaling by FGFR1 in disease 23/2735 38/10654 5.734170675692145e-6 2.0091595462143835e-5 1.012684335241364e-5 5295/8805/4893/11052/26127/5290/5335/9530/613/8074/9208/6776/6774/6772/399687/11064/2885/11160/3845/6777/3265/7750/1523 23 Measles_virus R-HSA-163685 Integration of energy metabolism 49/2735 108/10654 6.746288787518547e-6 2.357759091556227e-5 1.188390291249239e-5 2788/54331/59345/2770/10681/51764/112/94235/114/4082/108/150/113/5528/55970/2778/2194/111/107/10768/2792/152/5566/5519/2793/2785/2783/2784/2782/3630/2786/2771/5577/9370/7086/948/6844/47/8826/5518/196883/115/31/2791/109/2790/5515/2787/5516 49 Measles_virus R-HSA-8863795 Downregulation of ERBB2 signaling 19/2735 29/10654 7.22649790623665e-6 2.519160847721173e-5 1.269742232889043e-5 8065/2065/10273/207/10193/9101/2064/7316/1950/10000/3320/3084/208/4145/6233/7311/1956/11140/7314 19 Measles_virus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 22/2735 36/10654 7.34473390880294e-6 2.553879557121834e-5 1.28724163616744e-5 4893/71/5594/409/7414/673/6714/2244/2335/408/1445/5894/2266/8826/2243/7450/60/3845/3265/369/7529/5595 22 Measles_virus R-HSA-1268020 Mitochondrial protein import 33/2735 64/10654 7.899256839191635e-6 2.739742245491782e-5 1.3809227145928614e-5 2395/90639/10063/131118/56942/26520/3313/7416/51025/400916/10440/50/54927/10165/1678/3329/56993/26521/25813/100272147/10469/4580/8604/23203/26517/92609/10651/80273/9804/54543/388753/2671/131474 33 Measles_virus R-HSA-1236977 Endosomal/Vacuolar pathway 10/2735 11/10654 1.0362469299153505e-5 3.56698063815083e-5 1.797878831061809e-5 3135/3107/567/3106/1520/4012/3133/3134/3105/1514 10 Measles_virus R-HSA-2586552 Signaling by Leptin 10/2735 11/10654 1.0362469299153505e-5 3.56698063815083e-5 1.797878831061809e-5 3667/3953/9021/3952/6776/6774/3717/8660/6777/5781 10 Measles_virus R-HSA-9020956 Interleukin-27 signaling 10/2735 11/10654 1.0362469299153505e-5 3.56698063815083e-5 1.797878831061809e-5 10148/821/6774/6772/3717/9466/3716/246778/7297/3572 10 Measles_virus R-HSA-1643713 Signaling by EGFR in Cancer 17/2735 25/10654 1.0535746846240025e-5 3.608493294837208e-5 1.8188026134561725e-5 5295/4893/6464/5290/5335/7316/1950/867/3320/6233/2885/7311/1956/3845/3265/11140/7314 17 Measles_virus R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 17/2735 25/10654 1.0535746846240025e-5 3.608493294837208e-5 1.8188026134561725e-5 3135/3107/10484/6890/821/811/6892/6891/567/3106/10134/3309/2923/3133/3134/6396/3105 17 Measles_virus R-HSA-69231 Cyclin D associated events in G1 25/2735 44/10654 1.0960617109131272e-5 3.735334686445235e-5 1.8827349629720118e-5 8454/25/7027/1027/6500/5925/5934/7316/1869/5753/1026/5933/6714/1031/5519/4067/3717/6502/6233/7311/5518/1163/7314/5515/5516 25 Measles_virus R-HSA-69236 G1 Phase 25/2735 44/10654 1.0960617109131272e-5 3.735334686445235e-5 1.8827349629720118e-5 8454/25/7027/1027/6500/5925/5934/7316/1869/5753/1026/5933/6714/1031/5519/4067/3717/6502/6233/7311/5518/1163/7314/5515/5516 25 Measles_virus R-HSA-1980143 Signaling by NOTCH1 36/2735 73/10654 1.1497060439523161e-5 3.908429975718792e-5 1.9699808406235324e-5 8454/8841/79718/142678/892/23462/55534/3280/6500/409/84441/10013/23385/10046/7316/9978/9611/9759/9612/102/4609/10014/22938/1387/6907/2033/408/55294/3066/3065/83737/9794/6233/7311/3516/7314 36 Measles_virus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 16/2735 23/10654 1.238562211598195e-5 4.200074826459226e-5 2.1169797050766435e-5 7321/6497/64750/7323/54778/7316/9611/9612/23327/4088/142/3065/4087/6233/7311/7314 16 Measles_virus R-HSA-209560 NF-kB is activated and signals survival 11/2735 13/10654 1.4372038306422796e-5 4.845659363646535e-5 2.442376137189494e-5 4790/8878/7316/5970/4792/3654/7189/6233/7311/3551/7314 11 Measles_virus R-HSA-5357786 TNFR1-induced proapoptotic signaling 11/2735 13/10654 1.4372038306422796e-5 4.845659363646535e-5 2.442376137189494e-5 7124/7186/8737/841/27005/7128/7132/9099/8772/8717/1540 11 Measles_virus R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 24/2735 42/10654 1.4395498985431676e-5 4.845659363646535e-5 2.442376137189494e-5 2788/54331/59345/10681/51764/112/94235/114/55970/2778/111/2792/5566/2793/2785/2783/2784/2782/2786/5577/8826/2791/2790/2787 24 Measles_virus R-HSA-9006936 Signaling by TGF-beta family members 46/2735 102/10654 1.5509689471968078e-5 5.2079104354402615e-5 2.6249629240482604e-5 57154/5590/892/7027/11167/7321/51377/6497/10273/4738/91851/64750/7323/54778/7316/9611/5501/9612/6667/5933/4609/22938/23327/867/23645/92/4088/142/3065/9958/9040/4087/657/6233/7514/7048/1025/10272/7311/9110/387/7040/10589/5500/7314/4221 46 Measles_virus R-HSA-196299 Beta-catenin phosphorylation cascade 13/2735 17/10654 1.6606534074091443e-5 5.5490126052451896e-5 2.796889949320664e-5 1499/5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 13 Measles_virus R-HSA-432142 Platelet sensitization by LDL 13/2735 17/10654 1.6606534074091443e-5 5.5490126052451896e-5 2.796889949320664e-5 5777/5525/5526/338/5528/5519/1432/5529/5527/5518/5781/5515/5516 13 Measles_virus R-HSA-350054 Notch-HLH transcription pathway 18/2735 28/10654 1.8707358926438086e-5 6.235786308812695e-5 3.1430471137772786e-5 8841/79718/55534/84441/10013/10046/4854/9611/9759/9612/10014/22938/1387/6907/3066/3065/9794/3516 18 Measles_virus R-HSA-9022692 Regulation of MECP2 expression and activity 20/2735 33/10654 2.2887357512797388e-5 7.610601891391364e-5 3.8360006459875026e-5 818/815/8841/79718/817/9212/192670/9611/2874/9612/5566/6907/816/3066/3065/4204/1385/25942/4343/801 20 Measles_virus R-HSA-901042 Calnexin/calreticulin cycle 17/2735 26/10654 2.3150689167590854e-5 7.679526430895756e-5 3.870740944039658e-5 9695/10956/821/811/56886/84447/7316/5589/80267/6400/2923/6233/55741/7311/51009/267/7314 17 Measles_virus R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 36/2735 75/10654 2.4542489310471298e-5 8.121548395011033e-5 4.093534957454658e-5 5295/5290/3667/5291/2065/3815/8074/930/941/2064/2100/1950/2263/4233/6714/2099/8503/2261/5159/3084/2534/942/2885/7409/8660/3932/5293/5155/1956/4254/118788/5296/5781/5156/940/5879 36 Measles_virus R-HSA-5696394 DNA Damage Recognition in GG-NER 22/2735 38/10654 2.4734735295768172e-5 8.16544273619335e-5 4.115659189352929e-5 9318/10445/8450/7316/9978/64708/10980/1642/10920/142/10987/1069/6233/2873/7311/60/8533/50813/7314/51138/8451/7528 22 Measles_virus R-HSA-977443 GABA receptor activation 29/2735 56/10654 2.4964759113307218e-5 8.22156730414204e-5 4.143947869010509e-5 2788/54331/2770/2550/112/94235/114/108/113/55970/111/107/9568/2792/346562/2793/2785/2783/2784/2782/2786/2771/196883/3759/115/109/2773/2790/2787 29 Measles_virus R-HSA-1839124 FGFR1 mutant receptor activation 19/2735 31/10654 2.9369692122937748e-5 9.62595172450352e-5 4.851805095101275e-5 5295/8805/11052/26127/5290/9530/613/8074/9208/6776/6774/6772/399687/11064/2885/11160/6777/7750/1523 19 Measles_virus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 19/2735 31/10654 2.9369692122937748e-5 9.62595172450352e-5 4.851805095101275e-5 3725/1849/5594/5528/9261/5519/5598/1432/1385/2353/5518/1386/6197/5599/5600/51231/5595/5515/5516 19 Measles_virus R-HSA-400253 Circadian Clock 34/2735 70/10654 3.002177145223831e-5 9.816187801805844e-5 4.947690509400409e-5 8454/5187/26224/8945/8841/1374/79718/10135/1454/1407/6500/200186/6720/5465/7316/9611/5469/5501/64784/1387/2908/6907/2033/6256/6233/1385/7311/1386/23411/1453/8648/5500/10891/7314 34 Measles_virus R-HSA-5654743 Signaling by FGFR4 23/2735 41/10654 3.2604595849312824e-5 1.0613047886282575e-4 5.349334931541582e-5 5295/4893/6464/5290/5335/5594/8074/10817/7316/673/6714/867/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 23 Measles_virus R-HSA-8986944 Transcriptional Regulation by MECP2 31/2735 62/10654 3.261381868704353e-5 1.0613047886282575e-4 5.349334931541582e-5 818/815/8841/79718/5770/5468/4986/817/9212/6657/192670/54487/9611/2874/4233/9612/2289/5566/4988/6907/5728/816/3066/3065/4204/3654/1385/25942/4343/6750/801 31 Measles_virus R-HSA-8848021 Signaling by PTK6 28/2735 54/10654 3.3309433784375535e-5 1.0788161769407679e-4 5.437598248737179e-5 120892/1017/4893/5770/2065/207/9021/1027/898/2064/5921/7316/1950/5753/6774/867/2908/3084/6233/1398/7311/387/1956/9564/3845/3265/7314/5879 28 Measles_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 28/2735 54/10654 3.3309433784375535e-5 1.0788161769407679e-4 5.437598248737179e-5 120892/1017/4893/5770/2065/207/9021/1027/898/2064/5921/7316/1950/5753/6774/867/2908/3084/6233/1398/7311/387/1956/9564/3845/3265/7314/5879 28 Measles_virus R-HSA-9613829 Chaperone Mediated Autophagy 15/2735 22/10654 3.400528687818806e-5 1.0987557316773028e-4 5.5381003456036154e-5 2670/1915/1080/10013/5116/7316/3920/3320/6233/3326/7311/7431/3312/11315/7314 15 Measles_virus R-HSA-110056 MAPK3 (ERK1) activation 9/2735 10/10654 3.6895234146409284e-5 1.1782394121347488e-4 5.9387249662727245e-5 983/3717/3716/3570/7297/5781/3569/3572/5595 9 Measles_virus R-HSA-170660 Adenylate cyclase activating pathway 9/2735 10/10654 3.6895234146409284e-5 1.1782394121347488e-4 5.9387249662727245e-5 112/114/108/113/111/107/196883/115/109 9 Measles_virus R-HSA-2562578 TRIF-mediated programmed cell death 9/2735 10/10654 3.6895234146409284e-5 1.1782394121347488e-4 5.9387249662727245e-5 23643/11035/8737/841/7099/929/8772/353376/148022 9 Measles_virus R-HSA-8877330 RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) 9/2735 10/10654 3.6895234146409284e-5 1.1782394121347488e-4 5.9387249662727245e-5 4773/1378/865/3558/50943/3458/861/3559/1493 9 Measles_virus R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 9/2735 10/10654 3.6895234146409284e-5 1.1782394121347488e-4 5.9387249662727245e-5 2308/2309/4303/23410/7295/1387/10628/2033/23411 9 Measles_virus R-HSA-8852135 Protein ubiquitination 37/2735 79/10654 3.759857286376152e-5 1.1958890651264898e-4 6.0276851841949846e-5 11065/7319/7321/65264/9646/7320/10477/92912/79577/7336/7326/5591/7323/7316/7317/54926/55236/8915/5111/7415/3093/7322/9810/7347/118424/7328/7324/6233/7327/23168/7311/55284/27338/7334/3105/997/7314 37 Measles_virus R-HSA-9012852 Signaling by NOTCH3 26/2735 49/10654 3.7622495406534094e-5 1.1958890651264898e-4 6.0276851841949846e-5 142678/23462/4904/55534/3280/84441/23385/10460/10046/7316/1950/4854/102/6772/10320/11060/22938/1387/2033/9794/6233/7311/1956/9787/3516/7314 26 Measles_virus R-HSA-73887 Death Receptor Signalling 58/2735 141/10654 3.911536362247373e-5 1.2404640778423381e-4 6.25235831782231e-5 7124/1147/25999/81858/8841/7186/4790/6885/10018/7531/572/8737/8767/55072/9530/8878/1894/355/330/23421/23118/23385/841/27005/8517/4615/9500/6453/7316/5970/4792/7128/7132/329/9099/843/836/10616/10454/3066/3065/8567/3654/7189/6233/7410/7409/7311/387/8772/5599/8717/1540/3551/8743/7314/5879/257397 58 Measles_virus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 24/2735 44/10654 4.114812147709611e-5 1.301915159898884e-4 6.562092546244087e-5 892/7027/7321/6497/64750/7323/54778/7316/9611/9612/6667/5933/4609/22938/23327/4088/142/3065/4087/6233/1025/7311/7314/4221 24 Measles_virus R-HSA-76009 Platelet Aggregation (Plug Formation) 22/2735 39/10654 4.3039802941907935e-5 1.3586297242030847e-4 6.84795312391259e-5 151/5170/6464/5770/5747/207/150/6850/6714/152/4352/2244/2335/1445/2885/1398/2266/2243/7450/9564/2814/7066 22 Measles_virus R-HSA-70326 Glucose metabolism 41/2735 91/10654 4.542079663589837e-5 1.4304940549696727e-4 7.210173646255132e-5 23165/7167/5903/2597/55706/7175/9631/1468/8402/348995/79023/57122/23636/5214/10762/6576/23511/5528/53371/10165/23279/4927/9688/79902/5566/5519/9883/2023/23225/8604/5208/8086/9972/5518/8021/6396/129401/55746/8480/5515/5516 41 Measles_virus R-HSA-5675482 Regulation of necroptotic cell death 13/2735 18/10654 4.567391642761348e-5 1.4351666400419833e-4 7.233725054687213e-5 7186/8737/355/330/841/7316/329/6233/7311/8772/8717/8743/7314 13 Measles_virus R-HSA-381119 Unfolded Protein Response (UPR) 42/2735 94/10654 4.691483856382192e-5 1.4707855568063164e-4 7.413256436918505e-5 10525/10488/1200/9709/6464/8720/1965/9695/2673/37/4802/84699/7184/116138/5526/7494/811/1649/3576/468/84447/3484/5611/4800/1639/2081/51726/10130/8894/3309/7466/4801/4189/22926/6745/9451/6347/2931/467/167227/9820/22894 42 Measles_virus R-HSA-210990 PECAM1 interactions 10/2735 12/10654 4.773968844365278e-5 1.4898262680593236e-4 7.509228058754638e-5 5777/3635/5335/6714/4067/2534/7525/3685/3932/5781 10 Measles_virus R-HSA-3371511 HSF1 activation 10/2735 12/10654 4.773968844365278e-5 1.4898262680593236e-4 7.509228058754638e-5 6118/7531/1915/10013/7415/6119/3320/3326/6117/3297 10 Measles_virus R-HSA-9020591 Interleukin-12 signaling 25/2735 47/10654 5.013840760237534e-5 1.5611276912557776e-4 7.868611336640723e-5 3592/3593/6775/9446/3595/9987/4478/3313/3185/6647/3717/5306/3458/3181/998/5478/3716/3594/2939/302/7297/5062/5721/3586/5034 25 Measles_virus R-HSA-3371568 Attenuation phase 11/2735 14/10654 5.1400168686129446e-5 1.5895763227990372e-4 8.012002057289038e-5 3303/3337/3305/1387/3320/2033/3326/3306/3304/3312/3297 11 Measles_virus R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 11/2735 14/10654 5.1400168686129446e-5 1.5895763227990372e-4 8.012002057289038e-5 8841/79718/9611/2874/9612/5566/6907/3065/4204/25942/801 11 Measles_virus R-HSA-9005895 Pervasive developmental disorders 11/2735 14/10654 5.1400168686129446e-5 1.5895763227990372e-4 8.012002057289038e-5 8841/79718/9611/2874/9612/5566/6907/3065/4204/25942/801 11 Measles_virus R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 23/2735 42/10654 5.464718678980063e-5 1.6861857185141184e-4 8.498946072572123e-5 2788/10694/54331/59345/2770/10681/51764/94235/10576/55970/2792/346562/2793/2785/2783/2784/2782/2786/2771/2791/2773/2790/2787 23 Measles_virus R-HSA-451326 Activation of kainate receptors upon glutamate binding 19/2735 32/10654 5.493446732810679e-5 1.6912409042585684e-4 8.524425917738154e-5 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/1742/801/2791/2790/2787 19 Measles_virus R-HSA-3299685 Detoxification of Reactive Oxygen Species 21/2735 37/10654 5.676700625176741e-5 1.7437398781372502e-4 8.789038494491248e-5 4688/2876/2878/2936/7295/7001/10935/54205/9588/6647/2882/2877/493869/50507/538/1536/257202/5034/2880/7296/2950 21 Measles_virus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 39/2735 86/10654 5.783513649257681e-5 1.7725757716964256e-4 8.934381146622015e-5 5295/25/5290/5335/71/5291/5747/4690/5336/4627/4771/5594/4644/3055/6850/10768/4620/4641/6714/4067/3320/2534/998/695/2885/7525/1398/7410/10096/3326/5580/10097/7409/60/5296/5581/5058/5879/5595 39 Measles_virus R-HSA-1296041 Activation of G protein gated Potassium channels 16/2735 25/10654 5.984954674827652e-5 1.822086201003085e-4 9.183930448390501e-5 2788/54331/2550/94235/55970/9568/2792/2793/2785/2783/2784/2782/2786/3759/2790/2787 16 Measles_virus R-HSA-1296059 G protein gated Potassium channels 16/2735 25/10654 5.984954674827652e-5 1.822086201003085e-4 9.183930448390501e-5 2788/54331/2550/94235/55970/9568/2792/2793/2785/2783/2784/2782/2786/3759/2790/2787 16 Measles_virus R-HSA-997272 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits 16/2735 25/10654 5.984954674827652e-5 1.822086201003085e-4 9.183930448390501e-5 2788/54331/2550/94235/55970/9568/2792/2793/2785/2783/2784/2782/2786/3759/2790/2787 16 Measles_virus R-HSA-5674135 MAP2K and MAPK activation 22/2735 40/10654 7.256416122448508e-5 2.2042771813202784e-4 1.1110302197050346e-4 4893/71/5594/409/7414/673/6714/2244/2335/408/1445/5894/2266/8826/2243/7450/60/3845/3265/369/7529/5595 22 Measles_virus R-HSA-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle 20/2735 35/10654 7.479581772903088e-5 2.267041378070184e-4 1.142665496745325e-4 9695/5700/10956/821/811/56886/84447/7316/5589/7415/80267/6400/2923/51035/6233/55741/7311/51009/267/7314 20 Measles_virus R-HSA-2132295 MHC class II antigen presentation 51/2735 123/10654 8.770751235910875e-5 2.6525230007059375e-4 1.336961266587088e-4 1173/11258/1783/10484/10382/29127/1785/821/55860/3832/7277/10381/1780/1781/3122/8655/1639/832/285643/3113/5641/10121/26052/3796/10112/1062/7846/5476/56992/51143/10540/11004/1513/3835/1520/163/1759/10383/24137/84643/3127/9493/6396/81930/7879/140735/1075/8907/1508/1778/1514 51 Measles_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 14/2735 21/10654 9.160283016569324e-5 2.764226372841404e-4 1.393263542515529e-4 4893/4790/5970/5566/1387/4067/2534/2033/5894/30835/3845/3265/5058/5062 14 Measles_virus R-HSA-420092 Glucagon-type ligand receptors 19/2735 33/10654 9.842697350602622e-5 2.9636253561155147e-4 1.493767371196141e-4 2788/2692/54331/59345/10681/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 19 Measles_virus R-HSA-74751 Insulin receptor signalling cascade 27/2735 54/10654 1.0391792967471742e-4 3.1220956941746243e-4 1.5736417790077246e-4 5295/54106/5170/3643/4893/6464/5290/3667/5291/5594/2322/8074/57761/5140/2263/5289/2261/3630/208/2885/8660/5296/117145/3845/3265/5781/5595 27 Measles_virus R-HSA-8856828 Clathrin-mediated endocytosis 58/2735 146/10654 1.249422587919596e-4 3.745533797483253e-4 1.8878756597380053e-4 9318/1173/23396/7018/71/10618/8674/1856/4738/2060/1601/1785/409/1080/29978/29763/58513/950/338/6453/7316/1950/64708/26130/26052/10980/22848/2017/3949/867/1129/9146/10920/408/9829/10987/185/29979/6233/2885/2873/10096/6844/10097/163/7311/3575/1759/2580/1956/60/8533/51429/3312/154/50813/7314/51138 58 Measles_virus R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 12/2735 17/10654 1.3015399866990945e-4 3.8847707664003473e-4 1.958055799276702e-4 23643/7186/8737/355/841/7099/929/8772/353376/8717/8743/148022 12 Measles_virus R-HSA-164378 PKA activation in glucagon signalling 12/2735 17/10654 1.3015399866990945e-4 3.8847707664003473e-4 1.958055799276702e-4 112/114/108/113/2778/111/107/5566/5577/196883/115/109 12 Measles_virus R-HSA-937039 IRAK1 recruits IKK complex 11/2735 15/10654 1.4781947134591815e-4 4.3928996907572205e-4 2.214169955541096e-4 1147/8517/7316/7335/3654/7189/6233/7311/7334/3551/7314 11 Measles_virus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 11/2735 15/10654 1.4781947134591815e-4 4.3928996907572205e-4 2.214169955541096e-4 1147/8517/7316/7335/3654/7189/6233/7311/7334/3551/7314 11 Measles_virus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 15/2735 24/10654 1.5163123080124327e-4 4.496423943673231e-4 2.266349678870257e-4 596/2309/5747/207/5594/6722/1027/1950/10000/208/7514/1385/2353/1956/5595 15 Measles_virus R-HSA-211999 CYP2E1 reactions 9/2735 11/10654 1.5629267595906093e-4 4.594870516392993e-4 2.3159700797186348e-4 1558/1559/1572/1548/1571/29785/1553/1557/1555 9 Measles_virus R-HSA-2468052 Establishment of Sister Chromatid Cohesion 9/2735 11/10654 1.5629267595906093e-4 4.594870516392993e-4 2.3159700797186348e-4 10274/23244/10735/23047/5885/8243/9126/113130/157570 9 Measles_virus R-HSA-4755510 SUMOylation of immune response proteins 9/2735 11/10654 1.5629267595906093e-4 4.594870516392993e-4 2.3159700797186348e-4 51588/8517/10210/5970/4792/10401/7329/9641/4791 9 Measles_virus R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 9/2735 11/10654 1.5629267595906093e-4 4.594870516392993e-4 2.3159700797186348e-4 6885/23118/7316/10454/7189/6233/7311/7314/257397 9 Measles_virus R-HSA-202670 ERKs are inactivated 10/2735 13/10654 1.5896518890108597e-4 4.6336661445635694e-4 2.335524387886056e-4 1849/5594/5528/5519/5598/5518/51231/5595/5515/5516 10 Measles_virus R-HSA-209543 p75NTR recruits signalling complexes 10/2735 13/10654 1.5896518890108597e-4 4.6336661445635694e-4 2.335524387886056e-4 8767/8878/4615/7316/3654/7189/6233/7311/3551/7314 10 Measles_virus R-HSA-68884 Mitotic Telophase/Cytokinesis 10/2735 13/10654 1.5896518890108597e-4 4.6336661445635694e-4 2.335524387886056e-4 10274/23244/10735/23047/5885/10112/8243/9126/5347/9493 10 Measles_virus R-HSA-879415 Advanced glycosylation endproduct receptor signaling 10/2735 13/10654 1.5896518890108597e-4 4.6336661445635694e-4 2.335524387886056e-4 351/1650/5594/3958/5589/177/3146/6288/6285/5595 10 Measles_virus R-HSA-376176 Signaling by ROBO receptors 80/2735 218/10654 1.8317156564725973e-4 5.327920274665516e-4 2.685451940207898e-4 10921/5718/5689/25/23032/5684/9349/7852/5720/5682/6132/4690/6217/5700/122706/5707/6176/5690/5717/9491/23198/143471/5706/5705/10197/6232/23122/7316/10213/5709/9978/5695/5216/5714/6714/9861/5566/6130/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/1981/7408/5699/5710/5702/998/8453/5719/10487/5704/6233/5716/7311/387/3921/6188/23708/5694/23332/5058/5062/6168/5693/5721/5696/5691/7314/5879/6387/6230 80 Measles_virus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 37/2735 84/10654 1.860311755718937e-4 5.399633697743525e-4 2.7215979298653495e-4 9318/6118/10445/9557/7336/2072/8450/54778/7316/9978/64708/5425/5111/10980/6119/10401/1642/10920/142/10987/1069/7329/6233/2873/2968/7311/3980/60/8533/6117/7334/50813/7314/51138/8451/8554/7528 37 Measles_virus R-HSA-1489509 DAG and IP3 signaling 22/2735 42/10654 1.8943767101489863e-4 5.486883917344843e-4 2.765574990225292e-4 818/815/3838/5335/817/112/114/108/113/111/107/10768/5566/816/5577/5580/1385/5581/196883/115/801/109 22 Measles_virus R-HSA-2428924 IGF1R signaling cascade 26/2735 53/10654 2.067681049361752e-4 5.976208940138397e-4 0.00030122113443955347 5295/54106/5170/4893/6464/5290/3667/5291/2322/8074/57761/5140/2263/5289/2261/8471/208/2885/8660/3479/5296/117145/3845/3265/5781/3480 26 Measles_virus R-HSA-176187 Activation of ATR in response to replication stress 20/2735 37/10654 2.1150255029979664e-4 6.100178819173082e-4 3.0746963544967665e-4 1017/4172/6118/8318/8317/63967/4173/545/4174/993/4171/6119/990/995/4175/1111/55388/23595/6117/4176 20 Measles_virus R-HSA-354192 Integrin alphaIIb beta3 signaling 16/2735 27/10654 2.2184938144618663e-4 6.35844461467104e-4 3.2048710466570893e-4 5170/6464/5770/5747/207/6850/6714/2244/2335/1445/2885/1398/2266/2243/7450/9564 16 Measles_virus R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 16/2735 27/10654 2.2184938144618663e-4 6.35844461467104e-4 3.2048710466570893e-4 23643/7186/842/8737/355/841/7099/9500/836/929/8772/353376/8717/26060/8743/148022 16 Measles_virus R-HSA-9006921 Integrin signaling 16/2735 27/10654 2.2184938144618663e-4 6.35844461467104e-4 3.2048710466570893e-4 5170/6464/5770/5747/207/6850/6714/2244/2335/1445/2885/1398/2266/2243/7450/9564 16 Measles_virus R-HSA-6806834 Signaling by MET 35/2735 79/10654 2.3958901863100083e-4 6.852546044352215e-4 3.453914871375377e-4 5295/4893/6464/5290/85440/5770/5747/2060/284217/9101/3912/3688/7316/6774/4233/3915/6714/3673/867/9146/2335/5771/3914/3913/6233/2885/1398/7311/3845/3265/1399/5781/53916/7314/5879 35 Measles_virus R-HSA-418346 Platelet homeostasis 38/2735 88/10654 2.520246415470502e-4 7.193203310822057e-4 3.6256176503259854e-4 2788/5777/54331/5525/59345/6717/5526/10681/51764/94235/338/488/5528/55970/2778/2792/5027/5519/1432/2793/4843/2785/4846/2783/2784/5529/2782/2786/5527/5518/801/5781/4842/2791/2790/5515/2787/5516 38 Measles_virus R-HSA-8953750 Transcriptional Regulation by E2F6 19/2735 35/10654 2.8227253729209165e-4 8.039779128693671e-4 4.052320482845215e-4 23468/5888/7027/8317/6045/5931/4149/11335/1869/1876/5928/10138/23512/1111/672/5932/8726/648/6241 19 Measles_virus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 15/2735 25/10654 2.8930375688069324e-4 8.205924367009311e-4 4.136063299852561e-4 1849/5594/5528/9261/5519/5598/1432/1385/5518/6197/5600/51231/5595/5515/5516 15 Measles_virus R-HSA-211981 Xenobiotics 15/2735 25/10654 2.8930375688069324e-4 8.205924367009311e-4 4.136063299852561e-4 1576/1558/1559/1543/1544/1572/1548/1577/1571/1562/29785/1553/196/1557/1555 15 Measles_virus R-HSA-2172127 DAP12 interactions 22/2735 43/10654 2.94546087217892e-4 8.320167824505403e-4 4.1936458646757923e-4 5295/4893/6464/5290/5335/7305/5291/5336/54209/567/6850/54210/2534/695/2885/7410/3133/3932/5296/3845/3265/5879 22 Measles_virus R-HSA-5696395 Formation of Incision Complex in GG-NER 22/2735 43/10654 2.94546087217892e-4 8.320167824505403e-4 4.1936458646757923e-4 6118/9557/7336/2072/8450/54778/7316/9978/6119/10401/1642/142/1069/7329/6233/2968/7311/6117/7334/7314/8451/8554 22 Measles_virus R-HSA-210993 Tie2 Signaling 12/2735 18/10654 2.991141631545026e-4 8.414505205783749e-4 4.2411950941176633e-4 5295/4893/6464/5290/5291/7010/2888/2885/5296/3845/3265/5781 12 Measles_virus R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 12/2735 18/10654 2.991141631545026e-4 8.414505205783749e-4 4.2411950941176633e-4 7027/2810/5934/891/983/6790/5933/5111/2033/995/7157/3276 12 Measles_virus R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 26/2735 54/10654 3.022718391075273e-4 8.485910237240008e-4 4.2771856439719126e-4 5295/54106/5170/4893/6464/5290/3667/5291/2322/8074/57761/5140/2263/5289/2261/8471/208/2885/8660/3479/5296/117145/3845/3265/5781/3480 26 Measles_virus R-HSA-2559583 Cellular Senescence 72/2735 195/10654 3.050774875888431e-4 8.547160695229347e-4 4.3080579455016913e-4 1912/1017/7014/3725/11065/4790/9448/246184/7290/7027/7321/6045/8697/5594/1027/898/5931/7295/5925/472/192670/3576/3490/8881/7316/1869/890/6774/5970/1026/9261/6667/51433/1031/5598/3552/5928/1432/23512/119504/7157/8900/51529/23135/7324/64682/29945/10393/6233/51434/2353/51343/7311/25906/57634/4343/8726/6197/29882/5599/648/5600/23466/4217/3456/6416/5608/3569/7314/996/5595/4193 72 Measles_virus R-HSA-5628897 TP53 Regulates Metabolic Genes 37/2735 86/10654 3.3019167330446586e-4 9.23188964136976e-4 4.653184483087639e-4 9377/7531/7532/207/10971/2936/7249/7295/7533/2810/192670/7534/7001/54205/6341/64223/10000/2877/5728/6009/7157/8626/208/10542/2475/51204/6834/4343/1340/1327/4697/5564/2744/57521/7248/7529/7296 37 Measles_virus R-HSA-111996 Ca-dependent events 20/2735 38/10654 3.3946507047891356e-4 9.471835978739543e-4 4.7741255490227737e-4 818/815/3838/817/5594/112/114/108/113/111/107/5566/816/5577/5580/1385/196883/115/801/109 20 Measles_virus R-HSA-9614657 FOXO-mediated transcription of cell death genes 11/2735 16/10654 3.630160444878188e-4 0.0010108373596510402 5.094962027899212e-4 2308/2309/10018/4802/4303/1649/4800/1387/2033/4801/604 11 Measles_virus R-HSA-166663 Initial triggering of complement 14/2735 23/10654 3.757306660922731e-4 0.0010441197009055053 5.262716279631283e-4 5648/629/5199/3004/1401/717/716/715/78989/721/1675/720/4153/718 14 Measles_virus R-HSA-68875 Mitotic Prophase 55/2735 142/10654 3.938015752414505e-4 0.001092121777491472 5.504662973756479e-4 23165/4926/5903/55706/7175/9631/91754/5862/2801/5594/140609/5861/5925/348995/79023/9133/57122/23636/23310/10762/10051/23511/891/53371/26003/983/8548/23279/4927/9688/79902/8615/5519/81876/9883/23225/8086/9972/5518/55844/5347/54892/8021/6396/129401/84930/64689/55746/7112/10592/29781/8480/5595/5515/5516 55 Measles_virus R-HSA-2428928 IRS-related events triggered by IGF1R 25/2735 52/10654 4.041376127452296e-4 0.0011185222817393225 5.637730440422555e-4 5295/54106/5170/4893/5290/3667/5291/2322/8074/57761/5140/2263/5289/2261/8471/208/2885/8660/3479/5296/117145/3845/3265/5781/3480 25 Measles_virus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 32/2735 72/10654 4.0684114255669894e-4 0.0011237346074650758 5.664002324218898e-4 6517/71/7531/4627/7532/207/10971/57186/10382/7533/2810/4644/7277/10381/7534/8766/4641/7846/9847/51552/208/6844/9882/4012/10383/60/5564/801/4218/7529/5879/57148 32 Measles_virus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 64/2735 171/10654 4.2149693822041563e-4 0.0011618728478108038 5.856231949011811e-4 10921/5718/5689/23032/5684/9349/5720/5682/6132/6217/5700/122706/5707/6176/5690/5717/9491/23198/143471/5706/5705/10197/6232/7316/10213/5709/9978/5695/5714/9861/6130/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/1981/5699/5710/5702/8453/5719/5704/6233/5716/7311/3921/6188/23708/5694/6168/5693/5721/5696/5691/7314/6230 64 Measles_virus R-HSA-111933 Calmodulin induced events 19/2735 36/10654 4.548493379182174e-4 0.0012462871858959159 6.28170875103896e-4 818/815/3838/817/112/114/108/113/111/107/5566/816/5577/5580/1385/196883/115/801/109 19 Measles_virus R-HSA-111997 CaM pathway 19/2735 36/10654 4.548493379182174e-4 0.0012462871858959159 6.28170875103896e-4 818/815/3838/817/112/114/108/113/111/107/5566/816/5577/5580/1385/196883/115/801/109 19 Measles_virus R-HSA-156590 Glutathione conjugation 19/2735 36/10654 4.548493379182174e-4 0.0012462871858959159 6.28170875103896e-4 4258/2954/653689/2948/9446/4257/2938/2946/2953/4259/27306/2678/2944/2939/2937/2729/119391/2941/2950 19 Measles_virus R-HSA-2197563 NOTCH2 intracellular domain regulates transcription 9/2735 12/10654 4.819516385052838e-4 0.0013179116661721333 6.64272034582343e-4 2208/55534/3280/84441/10046/2033/9794/1385/3516 9 Measles_virus R-HSA-111931 PKA-mediated phosphorylation of CREB 13/2735 21/10654 4.853429793604293e-4 0.0013219083135661792 6.662864799841825e-4 112/114/108/113/111/107/5566/5577/1385/196883/115/801/109 13 Measles_virus R-HSA-901032 ER Quality Control Compartment (ERQC) 13/2735 21/10654 4.853429793604293e-4 0.0013219083135661792 6.662864799841825e-4 9695/10956/56886/84447/7316/80267/6400/6233/55741/7311/51009/267/7314 13 Measles_virus R-HSA-2465910 MASTL Facilitates Mitotic Progression 8/2735 10/10654 5.02926173146725e-4 0.001359553178877517 6.852607647665395e-4 891/983/5519/5518/55844/84930/5515/5516 8 Measles_virus R-HSA-450341 Activation of the AP-1 family of transcription factors 8/2735 10/10654 5.02926173146725e-4 0.001359553178877517 6.852607647665395e-4 3725/5594/1432/2353/1386/5599/5600/5595 8 Measles_virus R-HSA-74749 Signal attenuation 8/2735 10/10654 5.02926173146725e-4 0.001359553178877517 6.852607647665395e-4 3643/6464/3667/5594/3630/2885/8660/5595 8 Measles_virus R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 17/2735 31/10654 5.031339136429935e-4 0.001359553178877517 6.852607647665395e-4 857/1499/5525/1856/5526/1452/5528/89780/5519/2932/324/5529/5527/1857/5518/5515/5516 17 Measles_virus R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 43/2735 106/10654 5.319861426194454e-4 0.0014346870381666144 7.231307699095652e-4 9318/1173/7018/10618/8674/1856/4738/2060/1601/409/1080/29978/58513/950/338/6453/7316/1950/64708/10980/22848/3949/867/1129/9146/10920/408/10987/185/29979/6233/2885/2873/6844/163/7311/3575/1956/8533/154/50813/7314/51138 43 Measles_virus R-HSA-187687 Signalling to ERKs 18/2735 34/10654 6.098826301406117e-4 0.0016415308512625502 8.273870445088228e-4 4893/6464/5594/673/9261/6714/1432/4914/5603/2885/1398/3845/5600/3265/1399/6300/7529/5595 18 Measles_virus R-HSA-163615 PKA activation 12/2735 19/10654 6.223515787806585e-4 0.00167180718221471 8.426473388650402e-4 112/114/108/113/111/107/5566/5577/196883/115/801/109 12 Measles_virus R-HSA-3899300 SUMOylation of transcription cofactors 22/2735 45/10654 6.651876704284234e-4 0.0017833798600527205 8.988837404491621e-4 1912/1487/3622/6045/51588/4869/10210/9612/1387/10401/10521/2033/7329/4152/10155/9063/25942/648/11315/8648/10891/8554 22 Measles_virus R-HSA-5654732 Negative regulation of FGFR3 signaling 16/2735 29/10654 6.719281443958194e-4 0.0017979327301216263 9.06218878954888e-4 5594/8074/7316/673/6714/2261/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 16 Measles_virus R-HSA-8940973 RUNX2 regulates osteoblast differentiation 14/2735 24/10654 6.894698754997185e-4 0.0018412743263832637 9.280645087264087e-4 25/8841/23462/5594/3280/5925/10013/865/10413/6714/23314/7525/860/5595 14 Measles_virus R-HSA-73893 DNA Damage Bypass 23/2735 48/10654 7.235650237211714e-4 0.0019285682538871687 9.720635993468942e-4 6118/7320/9636/7706/8450/7316/9978/5425/5111/10459/7415/6119/1642/25898/7398/9246/57599/6233/7311/7318/6117/7314/8451 23 Measles_virus R-HSA-9034015 Signaling by NTRK3 (TRKC) 11/2735 17/10654 7.89929795153983e-4 0.0021013666395358383 0.0010591598275340069 5295/5800/4893/6464/5290/3667/5335/6714/2885/3845/3265 11 Measles_virus R-HSA-381042 PERK regulates gene expression 17/2735 32/10654 8.183901623306802e-4 0.002172857601536883 0.001095193689287895 9709/1965/4802/1649/3576/468/3484/4800/8894/3309/4801/22926/9451/6347/467/167227/22894 17 Measles_virus R-HSA-112043 PLC beta mediated events 25/2735 54/10654 8.200918948740669e-4 0.0021731642088539103 0.001095348229741195 818/815/3838/2770/817/5594/112/114/108/113/111/107/10768/346562/5566/816/2771/5577/5580/1385/196883/115/801/109/2773 25 Measles_virus R-HSA-198753 ERK/MAPK targets 13/2735 22/10654 9.084849604427418e-4 0.0024027497988543555 0.0012110671287348886 1849/5594/5528/5519/5598/1432/5518/6197/5600/51231/5595/5515/5516 13 Measles_virus R-HSA-422356 Regulation of insulin secretion 33/2735 78/10654 9.672370643344376e-4 0.0025532076650061266 0.0012869029798263686 2788/54331/59345/2770/10681/51764/112/94235/114/4082/150/55970/2778/111/10768/2792/152/5566/2793/2785/2783/2784/2782/3630/2786/2771/5577/948/6844/8826/2791/2790/2787 33 Measles_virus R-HSA-9609507 Protein localization 60/2735 163/10654 0.0010169689766548727 0.0026793221115714917 0.0013504689244647702 1891/2395/351/90639/10952/10063/7321/51/1528/131118/10965/51608/5621/56942/26520/8266/3313/23480/7416/7323/51025/7316/400916/10440/50/7917/54927/10165/1678/3329/7322/56993/1962/3416/26521/25813/100272147/118424/10469/4580/8604/4843/10455/23203/26517/92609/10651/8540/6233/4358/6844/80273/9804/7311/54543/388753/2671/3162/131474/7314 60 Measles_virus R-HSA-177929 Signaling by EGFR 23/2735 49/10654 0.0010359800223509624 0.0027189513996567403 0.0013704434254128478 5295/4893/6464/5290/5335/2060/58513/7316/1950/102/6714/867/9146/1445/998/6233/2885/7311/1956/3845/3265/5781/7314 23 Measles_virus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 23/2735 49/10654 0.0010359800223509624 0.0027189513996567403 0.0013704434254128478 1017/7027/1027/4869/898/2810/5934/1869/891/890/983/1026/6790/5933/5111/28984/2033/995/7157/8900/55835/3276/1263 23 Measles_virus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 16/2735 30/10654 0.0010991133053446355 0.0028791304556828883 0.0014511790848466958 6118/7320/8450/7316/9978/5425/5111/6119/1642/7398/57599/6233/7311/6117/7314/8451 16 Measles_virus R-HSA-112040 G-protein mediated events 25/2735 55/10654 0.001141286882295292 0.0029838989098178435 0.0015039859276530967 818/815/3838/2770/817/5594/112/114/108/113/111/107/10768/346562/5566/816/2771/5577/5580/1385/196883/115/801/109/2773 25 Measles_virus R-HSA-186797 Signaling by PDGF 26/2735 58/10654 0.0011804122668924615 0.003080313915509852 0.0015525823500380043 5295/4893/5290/5335/5291/5340/4690/5921/6778/6696/6776/6774/6772/6714/5159/2885/1398/5155/5296/9564/3845/6777/3265/1399/5781/5156 26 Measles_virus R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 46/2735 119/10654 0.0011898878386617806 0.003090865884889453 0.0015579008993372888 4899/8841/1374/79718/5468/29079/892/4802/6721/51/1543/57761/6720/5465/335/9611/5469/2874/4800/9612/6667/23309/336/3156/11010/1387/6907/9439/2033/2101/9967/4801/6256/7376/183/948/116519/9477/25942/196/9282/133522/8648/10891/10062/7296 46 Measles_virus R-HSA-167044 Signalling to RAS 12/2735 20/10654 0.0011934803307346866 0.003090865884889453 0.0015579008993372888 4893/6464/9261/6714/1432/4914/5603/2885/3845/5600/3265/6300 12 Measles_virus R-HSA-8876384 Listeria monocytogenes entry into host cells 12/2735 20/10654 0.0011934803307346866 0.003090865884889453 0.0015579008993372888 1499/2060/7316/4233/6714/867/999/9146/6233/2885/7311/7314 12 Measles_virus R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 12/2735 20/10654 0.0011934803307346866 0.003090865884889453 0.0015579008993372888 23462/55534/3280/84441/10046/22938/1387/4088/59/2033/9794/3516 12 Measles_virus R-HSA-9006115 Signaling by NTRK2 (TRKB) 14/2735 25/10654 0.001198772208287569 0.0030928774488775315 0.001558914795592517 5295/4893/6464/5290/5335/10817/6714/2534/2885/3845/3265/1020/5781/5879 14 Measles_virus R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 14/2735 25/10654 0.001198772208287569 0.0030928774488775315 0.001558914795592517 23462/55534/3280/84441/10046/4854/6772/10320/22938/1387/2033/9794/9787/3516 14 Measles_virus R-HSA-171007 p38MAPK events 9/2735 13/10654 0.0012086711501147266 0.0031125554053706306 0.0015688331509205787 4893/9261/6714/1432/5603/3845/5600/3265/6300 9 Measles_virus R-HSA-68962 Activation of the pre-replicative complex 17/2735 33/10654 0.001287564590805072 0.0033094999801181026 0.0016680998747272185 1017/4172/6118/8318/8317/4173/5422/4174/4171/6119/990/4175/81620/55388/23595/6117/4176 17 Measles_virus R-HSA-2514853 Condensation of Prometaphase Chromosomes 8/2735 11/10654 0.0014272821656471624 0.0036617538706678133 0.0018456477442628395 64151/9133/10051/891/983/23397/9918/10592 8 Measles_virus R-HSA-5654736 Signaling by FGFR1 23/2735 50/10654 0.0014579636695651022 0.003733477060381664 0.0018817986566349375 5295/4893/6464/5290/5335/5594/8074/10817/7316/673/6714/867/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 23 Measles_virus R-HSA-1592230 Mitochondrial biogenesis 38/2735 95/10654 0.0014862616605320438 0.003798840438300187 0.001914744008855107 4899/8841/55735/79718/3418/23410/200186/3313/5465/2553/9611/5469/10989/54927/54205/84303/64784/1432/1387/25813/6907/4580/2101/6256/10651/1385/1386/6742/5600/3054/5564/6300/801/133522/7019/8648/10891/139322 38 Measles_virus R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 25/2735 56/10654 0.0015654440580091683 0.0039937772057217135 0.002012998729891236 4899/8841/79718/3418/23410/200186/5465/2553/9611/5469/54205/64784/1387/6907/2101/6256/1385/1386/6742/3054/801/133522/7019/8648/10891 25 Measles_virus R-HSA-8949215 Mitochondrial calcium ion transport 13/2735 23/10654 0.0016010655430983463 0.004077062814209544 0.0020549774922177947 10730/11331/8165/7416/7417/6687/30968/3954/23203/221154/10367/10939/5245 13 Measles_virus R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 19/2735 39/10654 0.001610291759910506 0.004092949371201101 0.0020629848540206857 10694/26224/8841/8237/898/10517/10576/6774/26272/11328/26270/55294/26190/10238/7157/6468/54461/26234/84261 19 Measles_virus R-HSA-1296065 Inwardly rectifying K+ channels 16/2735 31/10654 0.0017348246564930494 0.004401314406287922 0.0022184112566460824 2788/54331/2550/94235/55970/9568/2792/2793/2785/2783/2784/2782/2786/3759/2790/2787 16 Measles_virus R-HSA-112399 IRS-mediated signalling 22/2735 48/10654 0.0019448969350619526 0.004925154900249307 0.0024824445751544717 5295/54106/5170/4893/5290/3667/5291/2322/8074/57761/5140/2263/5289/2261/208/2885/8660/5296/117145/3845/3265/5781 22 Molluscum_contagiosum_virus R-HSA-449147 Signaling by Interleukins 263/1497 461/10654 1.1068220895755932e-109 1.4344414280899689e-106 5.918585489520014e-107 5295/729230/8454/6095/3605/3557/7124/2308/54014/834/1052/10148/3725/7291/5777/596/9655/5601/351/1072/6464/2208/3592/5290/3566/1437/3667/4790/6885/6597/2309/5604/64109/3561/3587/5783/7412/6351/3578/7184/27250/27178/356/3593/3589/6775/207/50616/5292/5451/3684/9021/7422/29110/3553/2625/1230/1439/5594/3595/6624/4582/2919/6500/3082/5743/3091/941/1265/10538/4318/6367/3726/4312/3383/5705/58480/11009/6097/4478/6349/6657/1438/6778/53833/3576/4615/3581/3313/332/3662/3597/6776/5528/3688/2357/4313/7316/3565/4985/3934/6175/9978/2920/3560/3976/79155/6352/50615/6774/4314/1435/920/5970/1441/4792/4205/3055/5443/6850/1026/6348/9261/59307/3718/1440/3627/7133/3606/6772/8651/8809/4609/3146/6647/9861/5566/149233/6364/5519/8503/7132/4988/5598/1901/3552/1432/4208/5701/867/79923/6950/3558/4067/3717/23291/4088/3636/2247/598/836/5698/5708/3320/5602/29949/4843/2335/2534/595/9466/5771/5710/3458/3181/6288/5702/2002/7157/6648/942/3654/7189/163702/112744/5609/5704/6233/2885/7525/58985/3716/85480/7409/1385/2353/604/282618/6196/7311/53832/3594/1154/6363/2939/1270/50604/9846/6347/3932/3575/7076/302/1386/5296/7040/6935/3687/3588/51561/3570/8835/5599/5600/5784/7431/6777/6356/3600/5008/3977/3312/3559/3929/3551/23765/246778/55801/6773/7850/7297/6416/5781/3569/3162/1489/5062/4170/3689/1234/5696/3601/3586/4791/5724/3554/4692/7314/3572/3596/5595/59067/3556 263 Molluscum_contagiosum_virus R-HSA-168273 Influenza Viral RNA Transcription and Replication 124/1497 134/10654 2.0521882216365392e-94 1.3298179676204773e-91 5.4869032452176944e-92 6158/23165/6138/6144/2963/6203/5434/5440/5903/6227/9349/4736/6206/6194/6234/6191/55706/7175/6166/6128/51121/6132/9631/6159/6147/6129/6217/5430/6222/5436/6176/6152/6136/6125/6224/6146/348995/51065/6154/6141/6202/79023/6123/57122/5441/23636/6232/5438/6134/6169/10762/5431/6160/23511/6164/5435/6155/6175/5433/6218/53371/6209/6193/6173/23279/6210/4927/6231/6229/9688/11224/6205/6165/79902/6130/2962/6142/6167/6204/9883/6228/5437/23521/116832/23225/3320/6192/140801/6156/6235/6143/6181/5439/6124/6207/8086/6139/6233/7311/6223/25873/9972/3921/6188/6189/8021/6135/6201/129401/6161/9045/6187/5432/55746/6168/6208/6157/6137/6170/200916/8480/6122/6133/6230 124 Molluscum_contagiosum_virus R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 110/1497 112/10654 2.4108476896135615e-92 1.0414862019130586e-89 4.297230267802419e-90 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/1983/6176/6152/6136/8668/6125/8667/6224/6146/51065/6154/8662/6141/10480/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/6192/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 110 Molluscum_contagiosum_virus R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 109/1497 111/10654 1.7985843695030953e-91 5.827413357190029e-89 2.4044233150199277e-89 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/6176/6152/6136/8668/6125/8667/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/6192/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 109 Molluscum_contagiosum_virus R-HSA-168254 Influenza Infection 133/1497 155/10654 3.304869941405338e-91 8.566222888122635e-89 3.534471432071393e-89 3839/6158/23165/6138/6144/2963/3837/3838/6203/5434/5440/5903/6227/9349/4736/6206/6194/6234/6191/55706/7175/6166/6128/51121/6132/9631/6159/6147/6129/6217/5430/6222/5436/6176/6152/6136/6125/6224/6146/348995/51065/6154/6141/9636/6202/79023/6123/57122/5441/23636/6232/5438/6134/6169/10762/5431/6160/23511/6164/5435/6155/6175/5433/6218/53371/6209/6193/6173/23279/6210/4927/6231/6229/9688/11224/6205/6165/79902/6130/2962/6142/3840/6167/6204/9883/6228/5437/23521/116832/23225/3320/6192/140801/6156/6235/6143/6181/5439/6124/6207/8086/3836/6139/6233/7514/7311/6223/25873/9972/5610/3921/6188/6189/8021/7040/6135/6201/129401/6161/9045/6187/5432/55746/6168/6208/6157/6137/6170/200916/8480/6122/6133/6230 133 Molluscum_contagiosum_virus R-HSA-168255 Influenza Life Cycle 127/1497 144/10654 2.453837176805473e-90 5.300288301899822e-88 2.1869285716090884e-88 6158/23165/6138/6144/2963/3837/6203/5434/5440/5903/6227/9349/4736/6206/6194/6234/6191/55706/7175/6166/6128/51121/6132/9631/6159/6147/6129/6217/5430/6222/5436/6176/6152/6136/6125/6224/6146/348995/51065/6154/6141/6202/79023/6123/57122/5441/23636/6232/5438/6134/6169/10762/5431/6160/23511/6164/5435/6155/6175/5433/6218/53371/6209/6193/6173/23279/6210/4927/6231/6229/9688/11224/6205/6165/79902/6130/2962/6142/6167/6204/9883/6228/5437/23521/116832/23225/3320/6192/140801/6156/6235/6143/6181/5439/6124/6207/8086/3836/6139/6233/7514/7311/6223/25873/9972/3921/6188/6189/8021/6135/6201/129401/6161/9045/6187/5432/55746/6168/6208/6157/6137/6170/200916/8480/6122/6133/6230 127 Molluscum_contagiosum_virus R-HSA-72613 Eukaryotic Translation Initiation 112/1497 119/10654 1.8704372721160249e-87 3.0301083808279604e-85 1.2502396503091325e-85 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/1983/6176/6152/6136/8668/6125/8667/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/6192/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/1978/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 112 Molluscum_contagiosum_virus R-HSA-72737 Cap-dependent Translation Initiation 112/1497 119/10654 1.8704372721160249e-87 3.0301083808279604e-85 1.2502396503091325e-85 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/1983/6176/6152/6136/8668/6125/8667/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/6192/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/1978/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 112 Molluscum_contagiosum_virus R-HSA-72689 Formation of a pool of free 40S subunits 99/1497 101/10654 9.194161214799801e-83 1.3239592149311714e-80 5.462729704231929e-81 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/6176/6152/6136/8668/6125/8667/6224/6146/51065/6154/8662/6141/10480/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/8663/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 99 Molluscum_contagiosum_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 99/1497 108/10654 2.6611846857633903e-74 3.4488953527493535e-72 1.4230334951240025e-72 5295/6095/3605/7124/2308/1052/7291/596/9655/2208/3592/3566/2309/3561/7412/7184/356/3593/207/5292/5451/3684/9021/7422/3553/2625/6624/4582/3082/5743/3091/10538/4318/6367/3726/4312/3383/58480/6097/6657/6778/3576/332/3662/3597/3688/4313/3565/4985/3934/3976/6774/4314/5443/1026/3718/7133/3606/6772/8651/4609/149233/4988/1901/3552/79923/3717/2247/598/3320/4843/2335/595/6288/7157/112744/3716/2353/604/6347/7076/7040/6935/3687/51561/3570/7431/6356/5008/3312/3929/7297/3569/3162/4170/3689/3586/4692/3596 99 Molluscum_contagiosum_virus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 91/1497 95/10654 4.5069322798453616e-73 5.309985667890535e-71 2.1909297590061665e-71 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/6232/6134/6169/6160/6164/4686/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/1981/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/23708/6161/9045/5976/6187/6168/22916/6208/6157/6137/6170/200916/6122/6133/6230 91 Molluscum_contagiosum_virus R-HSA-156902 Peptide chain elongation 87/1497 89/10654 2.3266549866450356e-72 2.5127873855766382e-70 1.0367901168558581e-70 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/1938/6159/6147/6129/1915/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 87 Molluscum_contagiosum_virus R-HSA-156842 Eukaryotic Translation Elongation 89/1497 93/10654 2.3273117939978528e-71 2.3201508346317055e-69 9.573071994744205e-70 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/1917/1938/6159/6147/6129/1915/6217/1936/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 89 Molluscum_contagiosum_virus R-HSA-192823 Viral mRNA Translation 85/1497 89/10654 6.124592486824396e-68 5.669622759231726e-66 2.3393180325614987e-66 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 85 Molluscum_contagiosum_virus R-HSA-72764 Eukaryotic Translation Termination 87/1497 93/10654 2.5713376654580745e-67 2.2216357429557765e-65 9.16659322142247e-66 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/327/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/23708/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 87 Molluscum_contagiosum_virus R-HSA-5663205 Infectious disease 193/1497 383/10654 3.30214922464724e-67 2.6747408719642646e-65 1.1036130303426304e-65 3839/6158/928/23165/5905/6138/6144/2963/3837/3838/2237/6203/5434/5440/164/5903/6227/9349/4736/7852/6206/6194/6234/6191/55706/7175/6166/6128/51121/6132/9631/5604/1499/1938/3159/6159/6147/6129/6217/2959/5430/6874/6222/5436/6176/6152/6136/6125/4869/6500/6749/6224/6146/348995/51065/6154/6141/9636/6202/79023/6123/57122/5705/5441/23636/6232/5438/6134/3978/3981/6169/10762/5431/6160/919/23511/6164/5435/4686/7316/6155/6175/9978/5433/6218/6872/2960/53371/920/4233/567/3055/926/6209/6193/6714/6173/23279/6210/4927/5605/6231/6229/9688/11224/6205/6165/8731/9861/79902/6130/2962/6142/3840/6167/6204/9883/5701/867/6228/5437/23521/116832/23225/999/5698/5708/3320/6192/2534/140801/6156/6235/6143/5710/6181/5439/6124/5702/6207/8086/3836/6139/5609/5704/6233/2885/3326/7514/1025/7311/6223/25873/9972/3932/5610/6908/3921/6188/6189/8021/7040/7251/11198/6135/6201/129401/6161/2547/9045/2961/6187/6416/5062/5432/55746/6168/22916/6208/1234/6157/6137/5696/6170/200916/8480/6122/6133/2957/7314/5879/25920/6230 193 Molluscum_contagiosum_virus R-HSA-2408557 Selenocysteine synthesis 85/1497 93/10654 1.4494600725504186e-63 1.105000149426672e-61 4.559292364431038e-62 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 85 Molluscum_contagiosum_virus R-HSA-927802 Nonsense-Mediated Decay (NMD) 92/1497 115/10654 1.171349117033432e-57 7.989833977238569e-56 3.296650146553925e-56 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/6232/6134/6169/6160/6164/4686/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/1981/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/9775/6135/6201/23708/6161/9045/5976/6187/6168/22916/6208/6157/6137/6170/200916/6122/6133/6230 92 Molluscum_contagiosum_virus R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 92/1497 115/10654 1.171349117033432e-57 7.989833977238569e-56 3.296650146553925e-56 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/6232/6134/6169/6160/6164/4686/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/1981/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/9775/6135/6201/23708/6161/9045/5976/6187/6168/22916/6208/6157/6137/6170/200916/6122/6133/6230 92 Molluscum_contagiosum_virus R-HSA-1257604 PIP3 activates AKT signaling 144/1497 264/10654 1.336181643750422e-55 8.658457051502734e-54 3.572527763290602e-54 5295/1912/2308/27161/3725/6591/8841/5290/3667/2309/5468/1822/23186/842/3815/389541/2146/5978/9112/9219/8535/10273/207/51564/6045/57690/5594/4303/84335/84232/1027/7249/27327/80012/930/3082/5931/58528/1460/941/2064/5705/6199/192670/2260/4615/153129/5528/2100/7316/1950/2263/1457/4233/1026/1911/4734/6714/2099/1108/57167/2122/9861/7101/64223/10014/5519/8503/1958/5928/2932/2261/5701/84733/10325/5159/57459/2247/8649/3164/5698/5708/5880/54815/2534/23512/57332/5728/6009/5710/6615/3630/5702/192669/3066/3065/7157/1107/23028/8975/942/5987/3654/7189/5371/23112/10542/5704/6233/2885/79109/2475/55004/7409/1385/57504/7311/3932/2931/5155/1386/10670/1956/4254/5296/4343/8726/23466/26523/7874/5781/64121/53615/57521/5696/5156/7314/5879/6015/253260/28956/5595/4193/3556 144 Molluscum_contagiosum_virus R-HSA-9006925 Intracellular signaling by second messengers 156/1497 305/10654 3.1327081864786468e-55 1.9333284807982506e-53 7.977021347023323e-54 5295/1912/2308/818/27161/3725/6591/815/3838/8841/5290/3667/5335/2309/5468/1822/23186/842/3815/5567/389541/2146/5978/9112/9219/8535/817/10273/207/51564/6045/57690/5594/4303/84335/5568/84232/1027/7249/27327/80012/930/3082/5931/58528/1460/941/2064/5705/6199/192670/2260/4615/153129/5528/2100/7316/1950/2263/1457/4233/1026/1911/4734/6714/2099/1108/57167/2122/9861/7101/64223/5566/10014/5519/8503/1958/5928/2932/2261/5701/84733/10325/5159/57459/5576/2247/8649/3164/5698/5708/5880/54815/2534/23512/57332/5728/6009/5710/6615/816/3630/5702/192669/3066/3065/7157/1107/23028/8975/942/5987/3654/7189/5371/23112/10542/5704/6233/2885/79109/5580/2475/55004/7409/1385/57504/7311/3932/2931/5155/1386/10670/1956/4254/5296/5581/4343/8726/23466/26523/7874/5781/64121/53615/57521/5696/5156/7314/5879/6015/253260/28956/5595/4193/3556 156 Molluscum_contagiosum_virus R-HSA-913531 Interferon Signaling 122/1497 199/10654 8.069250446665817e-55 4.75352208130859e-53 1.961329773639347e-53 3839/23165/3665/818/3460/5777/815/3837/3838/5903/10379/5335/55706/7175/115362/960/5770/9631/3455/7412/2316/817/2633/9021/54739/9830/4600/348995/9636/317649/79023/2537/3383/57122/23636/11274/8638/25820/1982/7706/2634/10762/3662/9470/23511/7316/3394/53371/3663/8519/3664/567/4734/3434/6772/8651/23279/4927/9688/3659/3433/3106/79902/23586/8672/3840/3459/1958/25939/9883/4939/7341/3717/23225/1981/5771/1973/3458/3454/816/3661/8086/10346/7324/3836/9246/1977/5371/3439/51191/4599/6233/5580/3716/7311/9972/5610/5300/8021/9775/3127/4940/91543/3437/129401/3456/6773/4938/7297/5781/4261/3430/55746/3105/5696/3660/5724/1974/8480/7314/5595/8554 122 Molluscum_contagiosum_virus R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 85/1497 112/10654 6.19245452697432e-50 3.489313507373356e-48 1.4397102515802996e-48 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 85 Molluscum_contagiosum_virus R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 58/1497 59/10654 7.201752350939658e-49 3.8889462695074154e-47 1.6046009624023453e-47 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/8668/8667/6224/51065/8662/10480/26986/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/6192/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/8665/6201/1978/6187/6208/1974/1968/6230 58 Molluscum_contagiosum_virus R-HSA-72649 Translation initiation complex formation 57/1497 58/10654 5.2097193533958835e-48 2.5968447238465635e-46 1.0714726443421494e-46 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/8668/8667/6224/51065/8662/10480/26986/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/6192/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1974/1968/6230 57 Molluscum_contagiosum_virus R-HSA-72702 Ribosomal scanning and start codon recognition 57/1497 58/10654 5.2097193533958835e-48 2.5968447238465635e-46 1.0714726443421494e-46 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/1983/8668/8667/6224/51065/8662/10480/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/6192/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1974/1968/6230 57 Molluscum_contagiosum_virus R-HSA-376176 Signaling by ROBO receptors 120/1497 218/10654 6.750849974409399e-47 3.2404079877165114e-45 1.337010443274844e-45 6158/6138/6144/25/6203/6227/9349/4736/7852/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/5567/6222/6176/6152/6136/5532/5568/6125/27/6224/6146/51065/6154/6141/26986/6202/6123/5705/6232/6134/6169/6160/6164/4686/7316/6155/6175/9978/6218/6209/6193/6714/6173/6210/6231/6229/11224/6205/6165/9861/5566/6130/6142/6167/6204/5701/6228/23521/116832/5576/10486/5698/5708/6192/1981/140801/6156/6235/6143/5710/6181/6124/5702/6207/6139/10487/5704/6233/23380/7311/6223/25873/387/1630/3921/6188/6189/9775/6135/6201/23708/6161/9045/6187/5062/6168/22916/6208/6157/6137/5696/6170/200916/6122/6133/7314/5879/6387/6230 120 Molluscum_contagiosum_virus R-HSA-2408522 Selenoamino acid metabolism 85/1497 118/10654 7.861600525060191e-47 3.6387979573135744e-45 1.501388370951345e-45 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 85 Molluscum_contagiosum_virus R-HSA-8943724 Regulation of PTEN gene transcription 58/1497 61/10654 3.2983086598084496e-46 1.474002766590259e-44 6.081817782877287e-45 1912/3725/6591/8841/5468/1822/23186/389541/2146/5978/9112/9219/8535/51564/6045/5594/84232/80012/5931/58528/153129/1911/1108/57167/2122/7101/64223/10014/1958/5928/84733/10325/57459/8649/54815/23512/57332/6009/6615/3066/3065/7157/1107/23028/10542/2475/55004/57504/1386/10670/8726/23466/64121/53615/57521/6015/28956/5595 58 Molluscum_contagiosum_virus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 103/1497 171/10654 2.6249007199922835e-45 1.1339571110366665e-43 4.678770406161685e-44 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/5705/6232/6134/6169/6160/6164/4686/7316/6155/6175/9978/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/9861/6130/6142/6167/6204/5701/6228/23521/116832/5698/5708/6192/1981/140801/6156/6235/6143/5710/6181/6124/5702/6207/6139/5704/6233/7311/6223/25873/3921/6188/6189/9775/6135/6201/23708/6161/9045/6187/6168/22916/6208/6157/6137/5696/6170/200916/6122/6133/7314/6230 103 Molluscum_contagiosum_virus R-HSA-2262752 Cellular responses to stress 188/1497 479/10654 1.125770460615199e-44 4.7064468288945085e-43 1.941906261434707e-43 1912/1017/23165/818/6118/3725/84617/815/9134/1019/5903/5601/11065/573/4790/55706/7175/5241/9631/3159/112399/7531/7290/1029/1915/389541/2146/8535/51807/817/6045/7422/10382/57690/5594/84335/23677/1027/27327/80012/5931/58528/5925/3091/7277/348995/1051/10013/545/79023/472/10381/57122/5705/23636/192670/3576/7278/3313/153129/112714/1780/10762/3490/8881/29855/23511/7316/9978/2114/1869/890/53371/6774/5970/1026/1639/9261/1911/54205/6667/2289/23279/4927/9688/7415/1871/6647/8994/9861/79902/64223/4194/6119/5598/9883/3552/5928/1432/2932/5701/10524/1387/84733/10325/7846/23225/113457/2908/8649/5698/347733/5708/3320/5602/2033/23512/57332/10376/6009/5710/6767/25842/816/5702/192669/10540/7157/8900/6648/8086/23135/7324/22824/23112/5609/10542/5704/6233/2056/3326/2475/55004/2353/6196/7311/367/9972/538/2034/10383/10670/23411/84790/8021/4343/8726/55662/6117/5599/129401/5600/3312/23466/4217/26523/3456/528/2113/405/6416/3569/64121/3297/57521/55746/5696/7280/2288/8480/768/10728/7314/6015/28956/5595/4193/2950 188 Molluscum_contagiosum_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 66/1497 80/10654 3.267843363271697e-43 1.3234765621250374e-41 5.4607382517829684e-42 3839/23165/3837/3838/5903/5335/55706/7175/9631/2316/4600/348995/9636/317649/79023/57122/23636/11274/8638/25820/1982/7706/10762/9470/23511/7316/53371/4734/3434/6772/23279/4927/9688/79902/23586/8672/3840/9883/4939/23225/1981/1973/3661/8086/7324/3836/9246/1977/51191/4599/6233/3716/7311/9972/5610/5300/8021/9775/4940/129401/4938/55746/1974/8480/7314/5595 66 Molluscum_contagiosum_virus R-HSA-3700989 Transcriptional Regulation by TP53 157/1497 365/10654 3.826121054386678e-43 1.5026220868136773e-41 6.19990269737937e-42 1017/834/6118/2176/27161/3725/2963/9134/5434/5440/4436/9156/7531/1029/389541/5430/9219/6874/207/5436/22974/9212/57690/835/7832/4849/1027/4869/5982/7249/27327/5931/58528/4850/1460/6749/11200/545/472/5441/192670/332/5438/153129/5431/11073/9337/639/5435/7316/5433/1869/891/6872/28996/890/84289/1457/54971/983/1026/54205/6790/641/5111/25904/1108/246175/64223/4194/2962/5519/6119/1647/5928/3364/1432/10524/1387/4848/10325/5437/57459/23019/1616/9099/843/2821/8649/2177/5985/54815/2033/995/10128/84126/5728/6009/5439/1111/192669/3066/3065/7157/1107/55215/8900/5984/5371/23112/10498/10542/6233/79109/2475/55004/672/55571/1025/2353/604/7311/7161/839/1386/10670/6908/4513/8851/5300/5983/4343/6117/11198/50484/5600/57472/3276/85456/29883/26523/7874/1020/5884/5810/64121/53615/8795/5432/57521/26013/7529/7314/253260/28956/4193/25920 157 Molluscum_contagiosum_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 104/1497 182/10654 9.556777521015209e-43 3.642818725657562e-41 1.5030473624383055e-41 1912/6095/23165/7020/5905/5903/55706/7175/55143/5241/9631/5468/1029/8204/9112/8535/51564/1786/6045/9212/51588/3619/4869/3090/80012/7153/348995/79023/57122/23636/2516/332/10762/5465/5885/23511/28996/53371/1655/5970/4792/3190/6996/9759/9612/1911/6790/641/23137/5111/2099/23279/4927/9688/79902/9883/7341/1387/84733/10401/10521/1616/23225/2908/2033/23512/8243/9126/57332/142/3066/3065/23314/7157/1107/6256/8086/7329/5987/5371/7376/4152/672/10155/367/9972/9063/25942/8021/6117/6294/129401/11315/55746/8648/7421/6304/4791/8480/10891/10062/6015/4193/8554 104 Molluscum_contagiosum_virus R-HSA-8953897 Cellular responses to external stimuli 188/1497 493/10654 1.5496402728963726e-42 5.738096553353426e-41 2.3675707026506986e-41 1912/1017/23165/818/6118/3725/84617/815/9134/1019/5903/5601/11065/573/4790/55706/7175/5241/9631/3159/112399/7531/7290/1029/1915/389541/2146/8535/51807/817/6045/7422/10382/57690/5594/84335/23677/1027/27327/80012/5931/58528/5925/3091/7277/348995/1051/10013/545/79023/472/10381/57122/5705/23636/192670/3576/7278/3313/153129/112714/1780/10762/3490/8881/29855/23511/7316/9978/2114/1869/890/53371/6774/5970/1026/1639/9261/1911/54205/6667/2289/23279/4927/9688/7415/1871/6647/8994/9861/79902/64223/4194/6119/5598/9883/3552/5928/1432/2932/5701/10524/1387/84733/10325/7846/23225/113457/2908/8649/5698/347733/5708/3320/5602/2033/23512/57332/10376/6009/5710/6767/25842/816/5702/192669/10540/7157/8900/6648/8086/23135/7324/22824/23112/5609/10542/5704/6233/2056/3326/2475/55004/2353/6196/7311/367/9972/538/2034/10383/10670/23411/84790/8021/4343/8726/55662/6117/5599/129401/5600/3312/23466/4217/26523/3456/528/2113/405/6416/3569/64121/3297/57521/55746/5696/7280/2288/8480/768/10728/7314/6015/28956/5595/4193/2950 188 Molluscum_contagiosum_virus R-HSA-5663202 Diseases of signal transduction 159/1497 377/10654 2.269021029132532e-42 8.168475704877115e-41 3.3703587216354574e-41 5295/8454/4000/2308/818/2963/815/8805/5434/5440/11052/6464/26127/8841/5290/3667/5335/2309/5604/1499/10018/9734/842/3815/5430/8844/23462/817/207/51564/5436/1452/55534/5594/3280/4303/84335/613/1027/7249/6500/409/930/3082/84441/941/10533/10013/2064/5705/5441/6199/10046/2260/5438/9208/5431/6776/5528/2100/5435/4686/7316/9978/5433/1950/9611/6774/2263/4233/9759/9612/1026/6772/6714/2099/6934/5605/4609/7415/9861/64223/4089/10014/2962/5519/8850/8503/399687/2932/2261/5701/867/1387/5437/5159/3717/4088/2247/3164/5698/5708/5880/3320/2335/2534/2033/408/55294/5728/1445/5710/5439/816/5702/3066/3065/4087/942/9794/5704/6233/2885/79109/2475/7409/1385/7048/7311/9846/3932/2931/5155/1956/60/4254/5296/7040/3845/388585/6777/3265/3516/4763/5781/4851/5432/22916/5696/7750/5245/7529/5156/7314/1523/5879/253260/5595/4193 159 Molluscum_contagiosum_virus R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 50/1497 51/10654 5.2637798740197015e-42 1.8378585090701064e-40 7.583106908768793e-41 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/8668/8667/6224/51065/8662/10480/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/6204/8663/6228/8894/6192/6235/6207/6233/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1968/6230 50 Molluscum_contagiosum_virus R-HSA-6807070 PTEN Regulation 89/1497 140/10654 5.388782665483336e-42 1.8378585090701064e-40 7.583106908768793e-41 1912/27161/3725/6591/8841/5468/1822/23186/389541/2146/5978/9112/9219/8535/10273/207/51564/6045/57690/5594/84232/27327/80012/5931/58528/1460/5705/192670/153129/7316/1457/1911/4734/1108/57167/2122/9861/7101/64223/10014/1958/5928/5701/84733/10325/57459/8649/5698/5708/54815/23512/57332/5728/6009/5710/6615/5702/192669/3066/3065/7157/1107/23028/8975/5987/5371/23112/10542/5704/6233/2475/55004/57504/7311/1386/10670/4343/8726/23466/26523/7874/64121/53615/57521/5696/7314/6015/28956/5595 89 Molluscum_contagiosum_virus R-HSA-1169408 ISG15 antiviral mechanism 61/1497 72/10654 2.203343391039012e-41 7.321879576375795e-40 3.0210484281992395e-40 3839/23165/3837/3838/5903/5335/55706/7175/9631/4600/348995/9636/317649/79023/57122/23636/11274/25820/1982/7706/10762/9470/23511/7316/53371/4734/3434/6772/23279/4927/9688/79902/23586/8672/3840/9883/23225/1981/1973/3661/8086/7324/3836/9246/1977/51191/4599/6233/3716/7311/9972/5610/5300/8021/9775/129401/55746/1974/8480/7314/5595 61 Molluscum_contagiosum_virus R-HSA-2990846 SUMOylation 104/1497 188/10654 5.704033863666794e-41 1.8481069718280412e-39 7.625392638796662e-40 1912/6095/23165/7020/5905/5903/55706/7175/55143/5241/9631/5468/1029/8204/9112/8535/51564/1786/6045/9212/51588/3619/4869/3090/80012/7153/348995/79023/57122/23636/2516/332/10762/5465/5885/23511/28996/53371/1655/5970/4792/3190/6996/9759/9612/1911/6790/641/23137/5111/2099/23279/4927/9688/79902/9883/7341/1387/84733/10401/10521/1616/23225/2908/2033/23512/8243/9126/57332/142/3066/3065/23314/7157/1107/6256/8086/7329/5987/5371/7376/4152/672/10155/367/9972/9063/25942/8021/6117/6294/129401/11315/55746/8648/7421/6304/4791/8480/10891/10062/6015/4193/8554 104 Molluscum_contagiosum_virus R-HSA-6783783 Interleukin-10 signaling 45/1497 47/10654 2.023928970102871e-36 6.397590110373952e-35 2.639681429556505e-35 729230/3557/7124/2208/3592/1437/3587/6351/3593/3553/1230/2919/5743/941/6367/3383/6349/3576/2357/2920/3976/6352/6774/1435/6348/1440/3627/7133/3606/6364/7132/3552/942/3716/6363/6347/7076/3588/7850/7297/3569/1234/3586/5724/3554 45 Molluscum_contagiosum_virus R-HSA-69242 S Phase 85/1497 161/10654 1.29694219597251e-31 4.0019930618580306e-30 1.6512447006366793e-30 8454/1017/4172/6118/2237/9134/1019/994/5000/11065/8318/23594/207/9837/64785/1027/5982/6500/54107/5925/23244/4173/5705/4149/3978/8881/5885/5557/7316/5422/9978/1869/4174/5753/993/890/1026/5425/84515/5111/5426/4171/4609/9861/4998/6119/5928/2932/5701/5427/6502/5698/5708/5985/990/8243/9126/595/4175/5710/81620/5702/8900/5984/7324/5704/6233/23595/7311/84296/51659/23649/157570/5983/6117/5001/5981/7465/5558/5424/5696/4999/4176/7314/56655 85 Molluscum_contagiosum_virus R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 92/1497 185/10654 1.8109318190385659e-31 5.458064273195306e-30 2.2520278190247038e-30 6158/6138/6144/6203/6227/9349/4736/6206/6194/57418/6234/6191/6166/6128/51121/6132/6159/6147/25879/6129/6217/6222/6176/6152/6136/27043/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/26168/3921/6188/6189/26354/6135/6201/6161/9045/6187/4691/6168/6208/6157/6137/6170/200916/6122/6133/9188/6230 92 Molluscum_contagiosum_virus R-HSA-72766 Translation 120/1497 291/10654 6.67187508508893e-31 1.965170479608012e-29 8.108403213457362e-30 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/327/6166/6128/51121/6132/1917/1938/6159/6147/8666/6129/1915/6217/1936/6222/1983/6176/6152/6136/8668/6125/8667/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/9669/10240/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/6192/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/1978/23708/6161/9045/6187/6168/6208/6157/6137/6170/7284/1974/200916/6122/6133/1968/6230 120 Molluscum_contagiosum_virus R-HSA-453279 Mitotic G1-G1/S phases 80/1497 149/10654 1.7389959393454858e-30 5.0083083053149993e-29 2.0664559934210686e-29 8454/1017/4172/6118/25/9134/1019/5000/8318/23594/1029/8317/207/1027/6500/7153/54107/5925/4173/5705/4149/5557/7316/5422/1869/4174/891/5753/993/890/983/1026/84515/5111/5426/6714/4171/4609/1871/9861/51053/5519/4998/6119/5928/5701/10926/5427/4067/3717/6502/5698/5708/990/595/4175/5710/81620/5702/3065/8900/5704/6233/7298/55388/29935/23595/7311/23649/6117/1719/5001/7465/5558/5696/4999/4176/7314/6241/56655 80 Molluscum_contagiosum_virus R-HSA-8939211 ESR-mediated signaling 101/1497 223/10654 3.7900670103310826e-30 1.0678101837802355e-28 4.405844487982128e-29 5295/2788/3727/27161/3725/2354/2963/3838/596/5434/5440/6464/5290/54331/5241/4316/2309/5747/8204/5430/2770/207/5436/5451/2625/57690/5594/1027/3315/27327/4318/5441/192670/5438/5431/5885/2100/5435/4313/5433/1950/865/5469/1655/4314/6667/2289/6714/2099/4609/2962/8850/8503/10524/1387/5437/3320/2033/8243/4846/9126/595/2783/2782/5439/192669/3065/2002/861/23028/2786/23112/2771/10498/3326/7514/1385/1025/2353/1386/6908/1956/3169/5296/4343/3845/3276/3265/26523/8202/5432/8648/3480/2288/2773/10728/2957/5595/2787/7528/6387 101 Molluscum_contagiosum_virus R-HSA-69306 DNA Replication 72/1497 127/10654 1.4590654191528765e-29 4.023295283451336e-28 1.6600341163038326e-28 8454/1017/4172/6118/2237/9134/5000/11065/8318/23594/8317/9837/64785/5982/6500/54107/4173/5705/3978/8881/5557/7316/5422/9978/1869/4174/890/5425/84515/5111/5426/4171/1871/9861/51053/4998/6119/5701/10926/5427/6502/5698/5708/5985/990/4175/5710/81620/5702/8900/5984/7324/5704/6233/55388/29935/23595/7311/84296/51659/23649/5983/6117/5001/5981/5558/5424/5696/4999/4176/7314/56655 72 Molluscum_contagiosum_virus R-HSA-69206 G1/S Transition 73/1497 131/10654 2.67113982993705e-29 7.212077540830036e-28 2.975743494754433e-28 8454/1017/4172/6118/9134/1019/5000/8318/23594/8317/207/1027/6500/54107/5925/4173/5705/4149/5557/7316/5422/1869/4174/891/5753/993/890/983/1026/84515/5111/5426/4171/4609/9861/51053/5519/4998/6119/5928/5701/10926/5427/6502/5698/5708/990/595/4175/5710/81620/5702/3065/8900/5704/6233/7298/55388/29935/23595/7311/23649/6117/1719/5001/7465/5558/5696/4999/4176/7314/6241/56655 73 Molluscum_contagiosum_virus R-HSA-8868773 rRNA processing in the nucleus and cytosol 92/1497 195/10654 3.209091233252013e-29 8.487718853662468e-28 3.5020802287691147e-28 6158/6138/6144/6203/6227/9349/4736/6206/6194/57418/6234/6191/6166/6128/51121/6132/6159/6147/25879/6129/6217/6222/6176/6152/6136/27043/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/26168/3921/6188/6189/26354/6135/6201/6161/9045/6187/4691/6168/6208/6157/6137/6170/200916/6122/6133/9188/6230 92 Molluscum_contagiosum_virus R-HSA-68962 Activation of the pre-replicative complex 33/1497 33/10654 5.516287714086008e-29 1.4298217754910932e-27 5.899524544748826e-28 1017/4172/6118/5000/8318/23594/8317/54107/4173/5557/5422/4174/84515/5426/4171/51053/4998/6119/10926/5427/990/4175/81620/55388/29935/23595/23649/6117/5001/5558/4999/4176/56655 33 Molluscum_contagiosum_virus R-HSA-3371556 Cellular response to heat stress 58/1497 89/10654 1.4114018959942115e-28 3.586621288644114e-27 1.4798599858927959e-27 23165/818/6118/815/5903/573/55706/7175/9631/7531/1915/817/5594/84335/348995/10013/545/79023/472/57122/23636/3313/10762/23511/53371/9261/23279/4927/9688/7415/79902/64223/6119/9883/2932/1387/23225/3320/2033/6767/816/8086/22824/3326/2475/9972/23411/8021/6117/129401/3312/3297/57521/55746/2288/8480/10728/5595 58 Molluscum_contagiosum_virus R-HSA-176187 Activation of ATR in response to replication stress 35/1497 37/10654 5.233609881975269e-28 1.3043766167384517e-26 5.381930809804528e-27 1017/4172/6118/5000/8318/23594/8317/5982/63967/4173/545/4174/993/84515/4171/4998/6119/3364/10926/5985/990/995/84126/4175/1111/5984/55388/23595/5983/6117/5001/5884/5810/4999/4176 35 Molluscum_contagiosum_virus R-HSA-72312 rRNA processing 93/1497 205/10654 6.76456736090307e-28 1.654128169760449e-26 6.825025261844607e-27 6158/6138/6144/6203/6227/9349/4736/6206/6194/57418/6234/6191/6166/6128/51121/6132/6159/6147/25879/6129/6217/3028/6222/6176/6152/6136/27043/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/26168/3921/6188/6189/26354/6135/6201/6161/9045/6187/4691/6168/6208/6157/6137/6170/200916/6122/6133/9188/6230 93 Molluscum_contagiosum_virus R-HSA-168325 Viral Messenger RNA Synthesis 38/1497 43/10654 1.2800645721695737e-27 3.072154973206977e-26 1.2675883092829307e-26 23165/2963/5434/5440/5903/55706/7175/9631/5430/5436/348995/79023/57122/5441/23636/5438/10762/5431/23511/5435/5433/53371/23279/4927/9688/79902/2962/9883/5437/23225/5439/8086/9972/8021/129401/5432/55746/8480 38 Molluscum_contagiosum_virus R-HSA-69239 Synthesis of DNA 65/1497 119/10654 1.5245339663653777e-25 3.592356400744599e-24 1.4822263251935156e-24 8454/1017/4172/6118/2237/9134/5000/11065/8318/23594/9837/64785/5982/6500/54107/4173/5705/3978/8881/5557/7316/5422/9978/4174/890/5425/84515/5111/5426/4171/9861/4998/6119/5701/5427/6502/5698/5708/5985/990/4175/5710/81620/5702/8900/5984/7324/5704/6233/23595/7311/84296/51659/23649/5983/6117/5001/5981/5558/5424/5696/4999/4176/7314/56655 65 Molluscum_contagiosum_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 153/1497 473/10654 1.9622953897317494e-25 4.541312187664906e-24 1.873770785683701e-24 5295/54106/26999/4908/5777/627/2963/10253/5434/5440/6464/5290/2670/3667/5335/5241/5770/4915/5604/1499/5747/3815/5567/5430/10273/207/5436/7422/5594/5568/2322/7074/3315/3082/3178/4318/2064/5441/58513/6778/2260/5438/348/5431/6776/5528/9306/5435/3688/4686/7316/5433/1950/5753/9611/9047/6774/2263/4205/4233/9261/4734/10413/6772/6714/2099/8651/5605/64223/5566/8569/2962/5519/8503/5598/1432/2261/4208/867/5437/5159/4670/4067/3717/4909/2247/4914/3320/2335/2534/4846/4803/5771/1445/5439/1111/5603/3630/2002/83737/3913/3925/6233/2885/7525/3187/79109/5580/2475/7409/23191/1385/3685/6196/7311/9846/3932/3479/5155/3791/387/1956/60/4254/8851/5296/5581/3845/5600/6777/3265/6300/528/1020/5781/5062/5432/3480/22916/10603/10252/5725/4916/7529/5156/10787/7314/5879/253260/5595/25920/6387/2242 153 Molluscum_contagiosum_virus R-HSA-9006931 Signaling by Nuclear Receptors 111/1497 299/10654 4.696300221790262e-24 1.0677903662175754e-22 4.4057627196111786e-23 5295/2788/3727/27161/3725/2354/2963/3838/596/5434/5440/6464/8841/5290/54331/1374/5241/4316/2309/5747/8204/5430/2770/207/5436/5451/2625/57690/5594/1027/3315/27327/4318/5441/192670/5438/348/5431/5885/2100/5435/4313/5433/1950/9611/865/5469/1655/4314/9612/6667/2289/6714/2099/4609/2962/8850/8503/10524/1387/5437/5467/3320/2033/8243/4846/9126/595/2783/2782/5439/192669/3065/2002/861/23028/6256/2786/23112/2771/7376/10498/3326/7514/1385/1025/2353/1738/1386/6908/1956/3169/5296/4343/3845/3276/3265/26523/8202/5432/8648/3480/2288/2773/10728/2957/10062/5595/2787/7528/6387 111 Molluscum_contagiosum_virus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 49/1497 77/10654 1.2218561948846001e-23 2.7302166009835203e-22 1.1265026261368003e-22 1912/23165/5903/55706/7175/9631/1029/8535/51564/6045/51588/80012/348995/79023/57122/23636/10762/5885/23511/53371/6996/1911/641/23137/23279/4927/9688/79902/9883/7341/84733/23225/8243/9126/57332/142/8086/7329/5371/672/9972/9063/8021/6117/129401/55746/8480/6015/8554 49 Molluscum_contagiosum_virus R-HSA-4615885 SUMOylation of DNA replication proteins 36/1497 45/10654 3.5058263540410556e-23 7.700933821757979e-22 3.177448328015801e-22 23165/5905/5903/55706/7175/55143/9631/9212/51588/3619/7153/348995/79023/57122/23636/332/10762/23511/53371/6790/5111/23279/4927/9688/79902/9883/7341/10401/23225/8086/7329/9972/8021/129401/55746/8480 36 Molluscum_contagiosum_virus R-HSA-5633007 Regulation of TP53 Activity 74/1497 160/10654 4.7956675094639195e-23 1.0358641820442066e-21 4.274033499662582e-22 1017/6118/9156/1029/9219/6874/207/22974/9212/5982/5931/1460/6749/11200/545/472/11073/639/7316/6872/28996/890/84289/1457/54971/983/6790/641/1108/64223/4194/5519/6119/5928/3364/1432/10524/57459/1616/9099/5985/54815/2033/84126/1111/3066/3065/7157/1107/8900/5984/5371/6233/79109/2475/672/7311/7161/6908/8851/5300/5983/6117/11198/5600/7874/1020/5884/5810/53615/26013/7314/253260/4193 74 Molluscum_contagiosum_virus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 32/1497 38/10654 4.666258020553094e-22 9.913885892847228e-21 4.090524718621176e-21 23165/5903/55706/7175/9631/51588/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/7341/23225/8086/7329/5987/5371/9972/9063/8021/129401/55746/8480/4193/8554 32 Molluscum_contagiosum_virus R-HSA-69190 DNA strand elongation 29/1497 32/10654 4.9012213023329445e-22 1.0245133561005638e-20 4.227199357529942e-21 4172/6118/2237/8318/9837/64785/5982/4173/3978/5557/5422/4174/5425/84515/5111/4171/6119/5985/4175/5984/84296/51659/23649/5983/6117/5981/5558/5424/4176 29 Molluscum_contagiosum_virus R-HSA-909733 Interferon alpha/beta signaling 44/1497 69/10654 2.078123732006198e-21 4.2749973915556074e-20 1.7638878126301564e-20 3665/5777/10379/5770/3455/9021/54739/4600/9636/2537/11274/8638/2634/3662/3394/3663/8519/3664/3434/6772/8651/3659/3433/3106/1958/25939/4939/3454/3661/3439/4599/3716/4940/91543/3437/3456/6773/4938/7297/5781/3430/3105/5696/3660 44 Molluscum_contagiosum_virus R-HSA-5683057 MAPK family signaling cascades 105/1497 294/10654 2.666192559719302e-21 5.3990399334315867e-020 2.227674046607575e-20 2308/818/27161/2118/3725/815/9462/6464/6711/1437/3667/2309/1844/5604/3561/5747/3815/5567/8844/817/84292/1439/57690/5594/5568/2322/3315/27327/409/3082/2064/5705/1438/192670/2260/5528/7316/9978/1950/3560/2263/4233/983/5597/3718/6714/5605/4609/9861/5566/6710/5519/2261/5701/5159/3558/3717/2247/8649/5698/5708/2335/2534/408/1445/5710/816/5702/192669/1847/5979/23112/5704/6233/2885/6709/3716/7514/7311/5155/1956/60/4254/1843/4343/3570/3845/3265/3559/26523/4763/7297/5781/8202/3569/5062/5696/5245/7529/5156/7314/3572/5879/28956/5595 105 Molluscum_contagiosum_virus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 30/1497 35/10654 3.326172656163342e-21 6.631876557519524e-20 2.736349326851786e-20 23165/5903/55706/7175/9631/7884/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/1977/9972/8021/129401/55746/22916/8480 30 Molluscum_contagiosum_virus R-HSA-162906 HIV Infection 90/1497 233/10654 4.786062933049543e-21 9.398087213988193e-20 3.877703301418131e-20 23165/5905/2963/3837/2237/5434/5440/164/5903/7852/55706/7175/9631/3159/2959/5430/6874/5436/4869/6500/6749/348995/79023/57122/5705/5441/23636/5438/3978/3981/10762/5431/919/23511/5435/4686/7316/9978/5433/6872/2960/53371/920/567/3055/926/23279/4927/9688/8731/9861/79902/2962/9883/5701/5437/23225/5698/5708/2534/5710/5439/5702/8086/3836/5704/6233/7514/1025/7311/9972/3932/6908/8021/7251/11198/129401/2547/2961/5062/5432/55746/22916/1234/5696/8480/2957/7314/5879/25920 90 Molluscum_contagiosum_virus R-HSA-8878166 Transcriptional regulation by RUNX2 60/1497 121/10654 7.898371821087979e-21 1.5278044597208986e-19 6.303806575196691e-20 8454/57154/8493/7291/25/1019/8841/23462/10273/207/5594/3280/6500/4086/5925/10013/5705/3678/7316/9978/891/865/4094/9759/983/1026/10413/579/6772/6714/2099/9861/4089/2932/5701/6502/2908/5698/5708/2101/1749/595/55294/4488/5710/5702/23314/861/5704/6233/7525/7311/367/860/1750/133522/5696/10891/7314/5595 60 Molluscum_contagiosum_virus R-HSA-4570464 SUMOylation of RNA binding proteins 35/1497 47/10654 9.76060926257687e-21 1.8602572947499445e-19 7.675525550137849e-20 1912/23165/5903/55706/7175/9631/8535/6045/80012/348995/79023/57122/23636/10762/23511/53371/3190/1911/23279/4927/9688/79902/9883/7341/84733/23225/57332/8086/7329/9972/8021/129401/55746/8480/6015 35 Molluscum_contagiosum_virus R-HSA-159227 Transport of the SLBP independent Mature mRNA 29/1497 34/10654 2.064352471407763e-20 3.877392468035451e-19 1.5998337993518592e-19 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/1977/9972/8021/129401/55746/22916/8480 29 Molluscum_contagiosum_virus R-HSA-162587 HIV Life Cycle 68/1497 152/10654 2.8070915510537225e-20 5.197129500236606e-19 2.144364673586904e-19 23165/5905/2963/2237/5434/5440/5903/7852/55706/7175/9631/3159/2959/5430/6874/5436/6749/348995/79023/57122/5441/23636/5438/3978/3981/10762/5431/23511/5435/4686/7316/5433/6872/2960/53371/920/23279/4927/9688/8731/79902/2962/9883/5437/23225/5439/8086/3836/6233/7514/1025/7311/9972/6908/8021/7251/11198/129401/2547/2961/5432/55746/22916/1234/8480/2957/7314/25920 68 Molluscum_contagiosum_virus R-HSA-69002 DNA Replication Pre-Initiation 48/1497 85/10654 5.161060460098803e-20 9.42075261449021e-19 3.887055172320522e-19 1017/4172/6118/5000/8318/23594/8317/54107/4173/5705/5557/7316/5422/1869/4174/84515/5426/4171/1871/9861/51053/4998/6119/5701/10926/5427/5698/5708/990/4175/5710/81620/5702/5704/6233/55388/29935/23595/7311/23649/6117/5001/5558/5696/4999/4176/7314/56655 48 Molluscum_contagiosum_virus R-HSA-69620 Cell Cycle Checkpoints 102/1497 293/10654 8.785403154805743e-20 1.5813725678650337e-18 6.524831582808944e-19 1017/4172/6118/5905/11130/9134/5903/10403/5000/11065/8318/55143/9156/23594/7531/1029/1058/991/79019/8317/9212/51588/1027/3619/5982/63967/348995/4173/11200/545/79023/9133/472/57122/5705/6232/332/1780/8881/11073/5528/7316/4174/891/993/890/4085/983/1026/84515/641/4171/23279/9861/79902/4194/5519/4998/6119/3364/7341/5701/10524/699/10926/5698/5708/5985/990/995/84126/4175/5710/1111/5702/7157/8900/5984/7324/11004/5704/6233/55388/701/672/7514/23595/7311/5347/5983/6117/5001/7465/5884/5810/55746/5696/4999/4176/7529/7314/4193 102 Molluscum_contagiosum_virus R-HSA-4551638 SUMOylation of chromatin organization proteins 43/1497 71/10654 1.0959401746766729e-19 1.945669132028723e-18 8.027939563601295e-19 1912/23165/5903/55706/7175/9631/8535/6045/80012/348995/79023/57122/23636/10762/23511/53371/9759/1911/23279/4927/9688/79902/9883/7341/84733/23225/23512/57332/3066/3065/23314/1107/8086/7329/9972/9063/8021/129401/55746/6304/8480/6015/8554 43 Molluscum_contagiosum_virus R-HSA-168253 Host Interactions with Influenza Factors 32/1497 42/10654 1.4008657578195497e-19 2.453408138019103e-18 1.0122899074997602e-18 3839/23165/3837/3838/5903/55706/7175/9631/348995/9636/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/3840/9883/23225/8086/3836/9972/5610/8021/7040/129401/55746/8480 32 Molluscum_contagiosum_virus R-HSA-168276 NS1 Mediated Effects on Host Pathways 31/1497 40/10654 2.1787247261252214e-19 3.764836326744383e-18 1.553392506486474e-18 3839/23165/3837/3838/5903/55706/7175/9631/348995/9636/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/3840/9883/23225/8086/3836/9972/5610/8021/129401/55746/8480 31 Molluscum_contagiosum_virus R-HSA-2219528 PI3K/AKT Signaling in Cancer 52/1497 101/10654 3.7331406924805903e-19 6.365987286124797e-18 2.626641927673324e-18 5295/2308/5290/3667/2309/842/3815/207/4303/84335/1027/7249/930/3082/941/2064/6199/2260/2100/1950/2263/4233/1026/6714/2099/64223/8503/2932/2261/5159/2247/3164/5880/2534/5728/942/2885/79109/2475/7409/1385/3932/2931/5155/1956/4254/5296/5781/5156/5879/253260/4193 52 Molluscum_contagiosum_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 60/1497 129/10654 4.56330497390075e-19 7.680575644383601e-18 3.1690484302687374e-18 8454/3665/3725/5601/351/4790/6885/5604/8737/3684/29110/5594/4214/6500/841/7099/4615/5528/7316/79155/5970/4792/4205/9261/59307/8651/3146/5519/5598/1432/4208/329/23291/5602/114609/6288/2002/3661/695/3654/7189/5609/6233/1385/2353/6196/7311/1386/8772/5599/5600/7097/3929/3551/6416/5781/3689/4791/7314/5595 60 Molluscum_contagiosum_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 34/1497 48/10654 4.910130417881925e-19 8.158370540480737e-18 3.366189274337406e-18 5295/5777/6464/5290/1437/3561/1439/1438/6776/7316/3560/3055/6850/3718/5566/8503/867/3558/4067/3717/3636/2534/6233/2885/7525/3716/7409/7311/9846/5296/6777/3559/5781/7314 34 Molluscum_contagiosum_virus R-HSA-451927 Interleukin-2 family signaling 32/1497 44/10654 1.507019857079614e-18 2.4722756136394678e-17 1.02007473337301e-17 5295/5777/6464/5290/1437/3561/3578/6775/1439/1438/3581/6776/3560/50615/6774/6850/3718/6772/8503/3558/3717/3636/2885/3716/9846/3932/5296/6777/3600/3559/3601/59067 32 Molluscum_contagiosum_virus R-HSA-1226099 Signaling by FGFR in disease 39/1497 63/10654 1.864706423005746e-18 3.020824405269308e-17 1.2464090301143672e-17 5295/2963/8805/5434/5440/11052/26127/5290/5335/5430/5436/613/5441/2260/5438/9208/5431/6776/5435/4686/5433/6774/2263/6772/2962/399687/2261/5437/2247/5439/2885/9846/3845/6777/3265/5432/22916/7750/1523 39 Molluscum_contagiosum_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 49/1497 94/10654 2.0244574603173273e-18 3.2391319365077237e-17 1.3364839374154676e-17 8454/3665/3725/5601/351/4790/6885/5604/8737/29110/5594/6500/841/7098/5528/7316/79155/5970/4792/4205/9261/3146/5519/5598/1432/4208/329/23291/5602/6288/2002/3661/3654/7189/5609/6233/1385/2353/6196/7311/1386/8772/5599/5600/3551/6416/4791/7314/5595 49 Molluscum_contagiosum_virus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 41/1497 69/10654 2.11754759184138e-18 3.346758145154181e-17 1.380891112523005e-17 23165/6118/5903/573/55706/7175/9631/7531/5594/348995/545/79023/472/57122/23636/3313/10762/23511/53371/9261/23279/4927/9688/79902/6119/9883/2932/23225/6767/8086/22824/9972/23411/8021/6117/129401/3312/3297/55746/8480/5595 41 Molluscum_contagiosum_virus R-HSA-166208 mTORC1-mediated signalling 22/1497 23/10654 3.1015700157496123e-18 4.842933422182527e-17 1.9982213925184568e-17 6194/389541/84335/58528/6198/153129/64223/10325/8649/1981/6009/1977/10542/1975/2475/55004/10670/1978/64121/57521/7529/28956 22 Molluscum_contagiosum_virus R-HSA-2559583 Cellular Senescence 76/1497 195/10654 3.2560248614274716e-18 5.023581214773813e-17 2.0727576812094683e-17 1912/1017/3725/9134/1019/5601/11065/4790/3159/7290/1029/2146/8535/6045/57690/5594/1027/27327/80012/5931/5925/1051/472/192670/3576/3490/8881/29855/7316/2114/1869/890/6774/5970/1026/9261/1911/6667/1871/4194/5598/3552/5928/1432/10524/84733/5602/23512/57332/25842/192669/7157/8900/23135/7324/23112/5609/6233/2353/6196/7311/4343/8726/5599/5600/23466/4217/26523/3456/2113/6416/3569/7314/6015/5595/4193 76 Molluscum_contagiosum_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 49/1497 95/10654 3.620974972998458e-18 5.4567250755883734e-17 2.2514752586085884e-17 8454/3725/5601/351/4790/6885/5604/5594/4214/6500/7099/4615/5528/7316/79155/5970/4792/4205/9261/59307/8651/3146/5519/5598/1432/4208/23291/5602/114609/6288/2002/695/3654/7189/5609/6233/1385/2353/6196/7311/1386/5599/5600/7097/3551/6416/4791/7314/5595 49 Molluscum_contagiosum_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 49/1497 95/10654 3.620974972998458e-18 5.4567250755883734e-17 2.2514752586085884e-17 8454/3725/5601/351/4790/6885/5604/5594/4214/6500/7099/4615/5528/7316/79155/5970/4792/4205/9261/59307/8651/3146/5519/5598/1432/4208/23291/5602/114609/6288/2002/695/3654/7189/5609/6233/1385/2353/6196/7311/1386/5599/5600/7097/3551/6416/4791/7314/5595 49 Molluscum_contagiosum_virus R-HSA-877300 Interferon gamma signaling 48/1497 92/10654 4.312185253828006e-18 6.423669067771375e-17 2.6504417531090468e-17 3665/818/3460/5777/815/10379/115362/960/5770/7412/817/2633/9021/9830/3383/8638/7706/2634/3662/3394/3663/3664/567/6772/8651/3659/3106/3459/4939/7341/3717/5771/3458/816/3661/10346/5371/5580/3716/3127/4940/4938/5781/4261/3105/3660/5724/8554 48 Molluscum_contagiosum_virus R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 26/1497 31/10654 4.770494301847715e-18 7.02563706272118e-17 2.89881711164909e-17 23165/3837/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/3836/9972/8021/129401/55746/8480 26 Molluscum_contagiosum_virus R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 23/1497 25/10654 4.8658538450059904e-18 7.08555795857052e-17 2.9235408081171414e-17 10694/84617/51807/10575/10382/7277/10381/7278/112714/7203/10576/908/6950/7846/113457/347733/10376/10574/10383/84790/22948/10693/7280 23 Molluscum_contagiosum_virus R-HSA-166166 MyD88-independent TLR4 cascade 50/1497 99/10654 5.254761068085666e-18 7.483703674987938e-17 3.087817955566823e-17 8454/3665/3725/5601/351/4790/6885/5604/8737/29110/5594/6500/841/7099/5528/7316/79155/5970/4792/4205/9261/3146/5519/5598/1432/4208/329/23291/5602/6288/2002/3661/3654/7189/5609/6233/1385/2353/6196/7311/1386/8772/5599/5600/3551/6416/5781/4791/7314/5595 50 Molluscum_contagiosum_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 50/1497 99/10654 5.254761068085666e-18 7.483703674987938e-17 3.087817955566823e-17 8454/3665/3725/5601/351/4790/6885/5604/8737/29110/5594/6500/841/7099/5528/7316/79155/5970/4792/4205/9261/3146/5519/5598/1432/4208/329/23291/5602/6288/2002/3661/3654/7189/5609/6233/1385/2353/6196/7311/1386/8772/5599/5600/3551/6416/5781/4791/7314/5595 50 Molluscum_contagiosum_virus R-HSA-9018519 Estrogen-dependent gene expression 64/1497 150/10654 7.223204064688814e-18 1.017529616069207e-16 4.198384055906085e-17 3727/27161/3725/2354/2963/3838/596/5434/5440/5241/8204/5430/5436/5451/2625/57690/27327/5441/192670/5438/5431/5885/5435/5433/865/5469/1655/6667/2099/4609/2962/8850/10524/1387/5437/3320/2033/8243/9126/595/5439/192669/3065/861/23028/23112/10498/3326/1025/2353/1386/6908/3169/4343/3276/26523/8202/5432/8648/2288/10728/2957/7528/6387 64 Molluscum_contagiosum_virus R-HSA-1433557 Signaling by SCF-KIT 31/1497 43/10654 7.948478219158601e-18 1.1076589002182308e-16 4.570262518769179e-17 5295/5777/5290/3815/4318/6776/9306/6774/6772/6714/8651/8503/867/4067/3717/2534/1111/2885/7525/7409/9846/3932/4254/5296/3845/6777/3265/5781/10603/5879/2242 31 Molluscum_contagiosum_virus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 39/1497 65/10654 8.952723347134263e-18 1.2343329210517025e-16 5.092926607328338e-17 6118/5434/5440/5430/5436/5982/54107/5441/5438/3978/5431/8450/5435/7316/9978/5433/5425/5111/5426/6119/5437/5427/1642/5985/2033/5439/5984/6233/51426/7311/3980/5983/6117/5981/7874/5424/5432/7314/56655 39 Molluscum_contagiosum_virus R-HSA-177243 Interactions of Rev with host cellular proteins 28/1497 36/10654 1.057368423686826e-17 1.4424731337875017e-16 5.951724756043299e-17 23165/5905/3837/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/7514/9972/8021/129401/55746/8480 28 Molluscum_contagiosum_virus R-HSA-4085377 SUMOylation of SUMOylation proteins 27/1497 34/10654 1.5693282350444902e-17 2.1185931173100617e-16 8.741433589940801e-17 23165/5903/55706/7175/9631/51588/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/7341/23225/8086/7329/9972/8021/129401/55746/8480 27 Molluscum_contagiosum_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 49/1497 98/10654 1.941820529468728e-17 2.5679585777463996e-16 1.0595540590441611e-16 8454/3725/5601/351/4790/6885/5604/5594/4214/6500/7099/4615/5528/7316/79155/5970/4792/4205/9261/59307/8651/3146/5519/5598/1432/4208/23291/5602/114609/6288/2002/695/3654/7189/5609/6233/1385/2353/6196/7311/1386/5599/5600/7097/3551/6416/4791/7314/5595 49 Molluscum_contagiosum_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 49/1497 98/10654 1.941820529468728e-17 2.5679585777463996e-16 1.0595540590441611e-16 8454/3725/5601/351/4790/6885/5604/5594/4214/6500/7099/4615/5528/7316/79155/5970/4792/4205/9261/59307/8651/3146/5519/5598/1432/4208/23291/5602/114609/6288/2002/695/3654/7189/5609/6233/1385/2353/6196/7311/1386/5599/5600/7097/3551/6416/4791/7314/5595 49 Molluscum_contagiosum_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 32/1497 47/10654 3.4923743054974155e-17 4.571835454469344e-16 1.8863648561325755e-16 8454/8841/9734/23462/51564/55534/3280/6500/84441/3091/10013/10046/7316/9978/9611/9759/9612/4609/10014/8850/1387/2033/55294/3066/3065/9794/6233/7311/388585/3516/4851/7314 32 Molluscum_contagiosum_virus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 30/1497 42/10654 4.153798623394287e-17 5.383323015918996e-16 2.2211891586150503e-16 23165/5903/55706/7175/9631/7884/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/1977/9972/8021/129401/55746/22916/8480 30 Molluscum_contagiosum_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 47/1497 93/10654 5.099148094143686e-17 6.478917578441389e-16 2.673237597342614e-16 54106/8454/3665/3725/5601/351/4790/6885/5604/5594/4214/6500/7099/4615/5528/7316/79155/5970/4792/4205/9261/3146/5519/5598/1432/4208/23291/5602/6288/2002/3654/7189/5609/6233/51311/1385/2353/6196/7311/1386/5599/5600/3551/6416/4791/7314/5595 47 Molluscum_contagiosum_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 47/1497 93/10654 5.099148094143686e-17 6.478917578441389e-16 2.673237597342614e-16 54106/8454/3665/3725/5601/351/4790/6885/5604/5594/4214/6500/7099/4615/5528/7316/79155/5970/4792/4205/9261/3146/5519/5598/1432/4208/23291/5602/6288/2002/3654/7189/5609/6233/51311/1385/2353/6196/7311/1386/5599/5600/3551/6416/4791/7314/5595 47 Molluscum_contagiosum_virus R-HSA-168898 Toll-like Receptor Cascades 64/1497 155/10654 5.291062109215271e-17 6.657491741303875e-16 2.7469182948199877e-16 54106/8454/3665/3725/5601/351/4790/6885/5604/7184/8737/3684/29110/5594/4214/6500/841/7099/4615/7098/5528/7316/79155/5970/4792/4205/9261/59307/8651/3146/5519/5598/1432/4208/329/23291/5602/114609/6288/2002/3661/695/3654/7189/5609/6233/51311/1385/2353/6196/7311/1386/8772/5599/5600/7097/3929/3551/6416/5781/3689/4791/7314/5595 64 Molluscum_contagiosum_virus R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 27/1497 35/10654 5.950724372403131e-17 7.415518064071594e-16 3.0596841914785333e-16 23165/5903/55706/7175/9631/348995/79023/9133/57122/23636/10762/23511/891/53371/983/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 27 Molluscum_contagiosum_virus R-HSA-9009391 Extra-nuclear estrogen signaling 42/1497 77/10654 6.328336443612692e-17 7.810975267544809e-16 3.2228520434639076e-16 5295/2788/596/6464/5290/54331/4316/2309/5747/2770/207/5594/1027/3315/4318/2100/4313/1950/4314/6714/2099/8503/3320/4846/595/2783/2782/2002/2786/2771/7514/1385/2353/1956/5296/3845/3276/3265/3480/2773/5595/2787 42 Molluscum_contagiosum_virus R-HSA-180746 Nuclear import of Rev protein 26/1497 33/10654 9.012112572029931e-17 1.0915605507804477e-15 4.503839829406006e-16 23165/3837/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 26 Molluscum_contagiosum_virus R-HSA-180910 Vpr-mediated nuclear import of PICs 26/1497 33/10654 9.012112572029931e-17 1.0915605507804477e-15 4.503839829406006e-16 23165/5903/55706/7175/9631/3159/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/3836/9972/8021/129401/55746/8480 26 Molluscum_contagiosum_virus R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 25/1497 31/10654 1.2949860178222487e-16 1.5539832213866984e-15 6.41182160871055e-16 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/7514/9972/8021/129401/55746/8480 25 Molluscum_contagiosum_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 46/1497 92/10654 1.883112888638702e-16 2.218649366977962e-15 9.154271267257996e-16 1017/6118/9156/6874/22974/9212/5982/1460/6749/11200/545/472/11073/7316/6872/28996/890/1457/6790/641/4194/6119/3364/1432/10524/5985/84126/1111/7157/8900/5984/6233/672/7311/6908/8851/5300/5983/6117/11198/5600/1020/5884/5810/7314/4193 46 Molluscum_contagiosum_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 46/1497 92/10654 1.883112888638702e-16 2.218649366977962e-15 9.154271267257996e-16 54106/8454/3725/5601/351/4790/6885/5604/5594/4214/6500/7099/4615/5528/7316/79155/5970/4792/4205/9261/3146/5519/5598/1432/4208/23291/5602/6288/2002/3654/7189/5609/6233/51311/1385/2353/6196/7311/1386/5599/5600/3551/6416/4791/7314/5595 46 Molluscum_contagiosum_virus R-HSA-162599 Late Phase of HIV Life Cycle 59/1497 139/10654 1.9135629015272448e-16 2.234213982323702e-15 9.218491739932105e-16 23165/5905/2963/5434/5440/5903/55706/7175/9631/2959/5430/6874/5436/6749/348995/79023/57122/5441/23636/5438/10762/5431/23511/5435/4686/7316/5433/6872/2960/53371/23279/4927/9688/8731/79902/2962/9883/5437/23225/5439/8086/6233/7514/1025/7311/9972/6908/8021/7251/11198/129401/2961/5432/55746/22916/8480/2957/7314/25920 59 Molluscum_contagiosum_virus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 29/1497 41/10654 2.1497699900782848e-16 2.4875909885191583e-15 1.0263939426313615e-15 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/1977/9972/8021/129401/55746/22916/8480 29 Molluscum_contagiosum_virus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 42/1497 79/10654 2.1960335872633114e-16 2.518636751409957e-15 1.0392035978852001e-15 9318/6118/5434/5440/5430/5436/5982/54107/5441/5438/3978/5431/8450/5435/7316/9978/5433/5425/5111/5426/10980/6119/5437/5427/1642/5985/2033/5439/10987/5984/6233/51426/7311/3980/5983/6117/5981/7874/5424/5432/7314/56655 42 Molluscum_contagiosum_virus R-HSA-429947 Deadenylation of mRNA 22/1497 25/10654 2.3332438930245764e-16 2.6067966253102163e-15 1.0755788544977177e-15 9924/5073/4849/4850/255967/26986/10605/9337/25904/246175/4848/23019/1981/1973/1977/1975/55571/9775/57472/85456/29883/1974 22 Molluscum_contagiosum_virus R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 22/1497 25/10654 2.3332438930245764e-16 2.6067966253102163e-15 1.0755788544977177e-15 6118/5982/54107/3978/7316/5425/5111/5426/6119/5427/5985/5984/6233/51426/7311/3980/5983/6117/5981/5424/7314/56655 22 Molluscum_contagiosum_virus R-HSA-8854691 Interleukin-20 family signaling 22/1497 25/10654 2.3332438930245764e-16 2.6067966253102163e-15 1.0755788544977177e-15 6775/50616/11009/53833/6776/6774/3718/6772/3717/29949/163702/58985/3716/282618/53832/50604/3588/6777/55801/6773/7297/5781 22 Molluscum_contagiosum_virus R-HSA-2980766 Nuclear Envelope Breakdown 33/1497 52/10654 2.753994384481771e-16 3.050578395118269e-15 1.2586856925926582e-15 4000/23165/5903/55706/7175/9631/348995/79023/9133/57122/23636/7443/10762/23511/891/53371/983/23279/4927/9688/79902/9883/23225/8086/2010/64900/9972/5347/8021/129401/55746/7112/8480 33 Molluscum_contagiosum_virus R-HSA-5654738 Signaling by FGFR2 40/1497 73/10654 2.828312607084368e-16 3.1063501176113056e-15 1.2816974169481348e-15 5295/2963/10253/5434/5440/6464/5290/5335/5430/5436/5594/3178/5441/5438/5431/5435/4686/7316/5433/2263/6714/8569/2962/867/5437/4670/2247/5439/6233/2885/3187/7311/3845/3265/5781/5432/22916/5725/7314/5595 40 Molluscum_contagiosum_virus R-HSA-165054 Rev-mediated nuclear export of HIV RNA 26/1497 34/10654 3.320116166723274e-16 3.6103256820149776e-15 1.4896405510588113e-15 23165/5905/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/7514/9972/8021/129401/55746/8480 26 Molluscum_contagiosum_virus R-HSA-162909 Host Interactions of HIV factors 56/1497 129/10654 3.342894150013868e-16 3.6103256820149776e-15 1.4896405510588113e-15 23165/5905/3837/164/5903/55706/7175/9631/3159/4869/6500/348995/79023/57122/5705/23636/10762/919/23511/7316/9978/53371/920/567/3055/926/23279/4927/9688/9861/79902/9883/5701/23225/5698/5708/2534/5710/5702/8086/3836/5704/6233/7514/1025/7311/9972/3932/8021/129401/5062/55746/5696/8480/7314/5879 56 Molluscum_contagiosum_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 47/1497 97/10654 4.315986812000637e-16 4.622742899465145e-15 1.907369552410895e-15 54106/8454/3665/3725/5601/351/4790/6885/5604/5594/4214/6500/7099/4615/5528/7316/79155/5970/4792/4205/9261/3146/5519/5598/1432/4208/23291/5602/6288/2002/3654/7189/5609/6233/51311/1385/2353/6196/7311/1386/5599/5600/3551/6416/4791/7314/5595 47 Molluscum_contagiosum_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 57/1497 134/10654 5.548488963896852e-16 5.894132538696984e-15 2.431952022139432e-15 5295/8454/3725/5601/6464/4773/5290/2205/5335/4790/6885/4772/5532/5594/4775/4214/6500/5705/2206/5530/7316/5970/4792/6850/9861/5701/4067/23291/5698/5708/5602/2534/5710/5702/695/7189/5609/5704/6233/2885/7409/2353/7311/9846/5296/3845/5599/3265/3551/6416/5062/5696/997/2207/7314/5879/5595 57 Molluscum_contagiosum_virus R-HSA-3899300 SUMOylation of transcription cofactors 30/1497 45/10654 8.428214774461787e-16 8.880460445286565e-15 3.664127604130585e-15 1912/8204/8535/6045/51588/4869/80012/28996/1655/9612/1911/7341/1387/84733/10401/10521/1616/2033/57332/7329/4152/10155/9063/25942/6294/11315/8648/10891/6015/8554 30 Molluscum_contagiosum_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 43/1497 85/10654 1.052455566065583e-15 1.0825257250960284e-14 4.46656163376204e-15 8454/3725/5601/351/4790/6885/5604/5594/4214/6500/4615/5528/7316/79155/5970/4792/4205/9261/3146/5519/5598/1432/4208/23291/5602/6288/2002/3654/7189/5609/6233/1385/2353/6196/7311/1386/5599/5600/3551/6416/4791/7314/5595 43 Molluscum_contagiosum_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 43/1497 85/10654 1.052455566065583e-15 1.0825257250960284e-14 4.46656163376204e-15 8454/3725/5601/351/4790/6885/5604/5594/4214/6500/4615/5528/7316/79155/5970/4792/4205/9261/3146/5519/5598/1432/4208/23291/5602/6288/2002/3654/7189/5609/6233/1385/2353/6196/7311/1386/5599/5600/3551/6416/4791/7314/5595 43 Molluscum_contagiosum_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 43/1497 85/10654 1.052455566065583e-15 1.0825257250960284e-14 4.46656163376204e-15 8454/3725/5601/351/4790/6885/5604/5594/4214/6500/4615/5528/7316/79155/5970/4792/4205/9261/3146/5519/5598/1432/4208/23291/5602/6288/2002/3654/7189/5609/6233/1385/2353/6196/7311/1386/5599/5600/3551/6416/4791/7314/5595 43 Molluscum_contagiosum_virus R-HSA-6782135 Dual incision in TC-NER 37/1497 66/10654 1.3752757714464872e-15 1.4034310234603522e-14 5.790634827143104e-15 6118/5434/5440/5430/5436/5982/54107/5441/5438/5431/8450/5435/7316/9978/5433/5425/5111/5426/6119/5437/5427/1642/5985/2033/5439/5984/6233/51426/7311/5983/6117/5981/7874/5424/5432/7314/56655 37 Molluscum_contagiosum_virus R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 21/1497 24/10654 1.4801755421128816e-15 1.4870600795180577e-14 6.1356929856658005e-15 6118/2237/5982/54107/3978/5557/5422/5425/5111/5426/6119/5427/5985/5984/23649/5983/6117/5981/5558/5424/56655 21 Molluscum_contagiosum_virus R-HSA-982772 Growth hormone receptor signaling 21/1497 24/10654 1.4801755421128816e-15 1.4870600795180577e-14 6.1356929856658005e-15 5777/3667/5770/2690/9021/5594/6776/6774/6772/8651/1442/4067/3717/5618/2688/1154/5617/8835/6777/2689/5595 21 Molluscum_contagiosum_virus R-HSA-8878159 Transcriptional regulation by RUNX3 46/1497 96/10654 1.528197256441327e-15 1.523495111036892e-14 6.2860259617181714e-15 57154/2309/1499/10018/1029/55534/3280/84441/463/5705/6097/10046/7316/865/9759/1026/10413/6714/6934/4609/9861/4089/8850/5701/1387/4088/5698/5708/2033/595/5710/5702/7157/861/9794/5704/6233/7311/7040/3845/3516/4851/5696/3676/7314/4193 46 Molluscum_contagiosum_virus R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 25/1497 33/10654 1.8354464683843455e-15 1.8158310099435967e-14 7.492220216466433e-15 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/7514/9972/8021/129401/55746/8480 25 Molluscum_contagiosum_virus R-HSA-5696398 Nucleotide Excision Repair 50/1497 111/10654 2.1182284884821208e-15 2.0797152432369912e-14 8.581021309002532e-15 9318/6118/5434/5440/5430/83444/5436/5982/54107/5441/5438/3978/5431/8450/5435/7316/9978/5433/5425/5111/5426/10980/6119/7341/5437/10401/5427/1642/5985/2033/142/5439/10987/5984/7329/6233/51426/7311/3980/60/5983/6117/5981/7874/5424/5432/7314/8554/7528/56655 50 Molluscum_contagiosum_virus R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 24/1497 31/10654 2.896899706313666e-15 2.801777626404859e-14 1.1560291051118164e-14 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 24 Molluscum_contagiosum_virus R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 24/1497 31/10654 2.896899706313666e-15 2.801777626404859e-14 1.1560291051118164e-14 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 24 Molluscum_contagiosum_virus R-HSA-176033 Interactions of Vpr with host cellular proteins 26/1497 36/10654 3.4928867010002946e-15 3.353171232960283e-14 1.3835371883884209e-14 23165/5903/55706/7175/9631/3159/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/3836/9972/8021/129401/55746/8480 26 Molluscum_contagiosum_virus R-HSA-8878171 Transcriptional regulation by RUNX1 81/1497 239/10654 3.5235273941452656e-15 3.3577143403031356e-14 1.3854116998651666e-14 1912/6595/9070/27161/25/4773/2624/1437/11091/6597/640/8535/8085/6045/9021/2625/57690/5929/27327/80012/1460/4005/6598/5705/6599/192670/100506658/7316/865/28996/1457/1911/10413/6714/2099/122809/9861/8850/5701/1387/84733/3558/6604/8289/5698/5708/10138/2033/6605/6602/57332/595/50943/5710/3458/5702/192669/3065/83737/861/5371/23112/5704/6233/7311/6688/7161/860/58508/25942/4343/3276/3977/6601/3559/23466/26523/5781/5696/7314/6015 81 Molluscum_contagiosum_virus R-HSA-68886 M Phase 114/1497 395/10654 5.055805717899156e-15 4.782718401749859e-14 1.9733763386037426e-14 4000/23165/5905/11130/84617/5903/10403/11065/55706/7175/55143/64151/22981/9631/7531/1058/991/203068/79019/54801/51807/10382/9212/5594/3619/5925/1460/23244/7277/348995/79023/9133/10381/57122/5705/23636/23310/7278/6232/332/7443/112714/1780/10762/8881/10051/5885/23511/5528/7316/891/53371/4085/1457/983/1639/23279/4927/9688/9861/79902/5566/5519/9883/5701/10112/699/7846/23225/113457/5698/347733/5708/3320/8243/9126/10376/10426/23397/5710/9918/5702/10540/10733/8086/7324/2010/64900/11004/9232/5704/6233/9700/701/7514/7311/9972/55844/10383/5347/54892/84790/8021/9493/129401/6418/55746/7112/5696/10592/7280/8480/7314/5595 114 Molluscum_contagiosum_virus R-HSA-69481 G2/M Checkpoints 64/1497 168/10654 5.659463573434396e-15 5.314974486355781e-14 2.1929881733826643e-14 1017/4172/6118/5000/8318/9156/23594/7531/8317/51588/5982/63967/4173/11200/545/9133/472/5705/11073/7316/4174/891/993/983/84515/641/4171/9861/4998/6119/3364/7341/5701/10524/10926/5698/5708/5985/990/995/84126/4175/5710/1111/5702/7157/5984/5704/6233/55388/672/23595/7311/5983/6117/5001/7465/5884/5810/5696/4999/4176/7529/7314 64 Molluscum_contagiosum_virus R-HSA-8851708 Signaling by FGFR2 IIIa TM 18/1497 19/10654 6.884115286848193e-15 6.418570799823927e-14 2.6483381792645833e-14 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2263/2962/5437/2247/5439/5432/22916 18 Molluscum_contagiosum_virus R-HSA-448424 Interleukin-17 signaling 38/1497 72/10654 8.168601054063261e-15 7.561790690047134e-14 3.1200370943339376e-14 8454/3605/3725/5601/4790/6885/5604/5594/6500/5528/7316/79155/4205/9261/5519/5598/1432/4208/23291/5602/2002/3654/7189/112744/5609/6233/1385/2353/6196/7311/1386/5599/5600/3551/23765/6416/7314/5595 38 Molluscum_contagiosum_virus R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 24/1497 32/10654 1.0047907926156315e-14 9.235523881062826e-14 3.8106287618420363e-14 10694/84617/51807/10575/10382/7277/10381/7278/112714/7203/10576/908/6950/7846/113457/347733/10376/10574/10383/60/84790/22948/10693/7280 24 Molluscum_contagiosum_virus R-HSA-9607240 FLT3 Signaling 86/1497 267/10654 1.44907661454836e-14 1.3225375298976583e-13 5.456863752339265e-14 5295/54106/818/815/9462/6464/6711/5290/1437/3667/1844/5604/3561/5747/3815/8844/817/84292/1439/5594/2322/409/3082/2064/5705/1438/2260/6776/5528/7316/9978/1950/3560/2263/4233/3055/3718/6714/5605/9861/6710/5519/2261/5701/5159/3558/3717/2247/8649/5698/5708/2335/2534/408/1445/5710/816/5702/1847/5979/5704/6233/2885/6709/3716/7311/9846/5155/1956/60/4254/5296/1843/3845/6777/3265/3559/4763/5781/5696/5245/7529/5156/7314/28956/5595 86 Molluscum_contagiosum_virus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 23/1497 30/10654 1.6196704550606263e-14 1.467897139691309e-13 6.05662562510709e-14 6118/5982/54107/8450/7316/9978/5425/5111/5426/6119/5427/1642/5985/5984/6233/7311/5983/6117/5981/5424/7314/51514/56655 23 Molluscum_contagiosum_virus R-HSA-400253 Circadian Clock 37/1497 70/10654 1.7349884789038748e-14 1.5614896310134872e-13 6.442793474292167e-14 8454/6095/8841/1374/5936/10135/8204/28999/1407/6500/3091/1408/5465/406/4209/7316/9611/5469/8553/4208/1387/2908/6604/1390/2033/6256/10498/6233/1385/7311/23054/1386/23411/23373/8648/10891/7314 37 Molluscum_contagiosum_virus R-HSA-190236 Signaling by FGFR 42/1497 87/10654 1.8850666025107376e-14 1.6848595288647697e-13 6.95182456679096e-14 5295/2963/10253/5434/5440/6464/5290/5335/5430/5436/5594/3178/5441/2260/5438/5431/5435/4686/7316/5433/2263/6714/8569/2962/2261/867/5437/4670/2247/5439/6233/2885/3187/7311/3845/3265/5781/5432/22916/5725/7314/5595 42 Molluscum_contagiosum_virus R-HSA-73894 DNA Repair 100/1497 334/10654 2.0291718606274437e-14 1.801237487241895e-13 7.432006526306716e-14 9318/1017/6118/2176/54962/25/3838/2237/5434/5440/2178/4436/151987/5888/9156/328/5430/83444/5436/51588/2956/5982/63967/54107/5531/9636/11200/545/472/5441/7706/5438/3978/3981/5431/11073/5591/8450/5435/7316/9978/5433/890/6996/5425/641/5111/5426/7415/10980/6119/83932/3364/22976/7341/10524/5437/10401/5427/2177/1642/5985/2033/84126/142/8914/5439/1111/10987/7157/55215/8900/5984/7329/9246/6233/51426/672/7311/6047/3980/60/5983/6117/5599/5981/7874/2547/5884/5810/5424/5432/348654/55183/7314/51514/7374/8554/7528/56655 100 Molluscum_contagiosum_virus R-HSA-5684996 MAPK1/MAPK3 signaling 83/1497 255/10654 2.1834447917721035e-14 1.9249962245827524e-13 7.942641992268018e-14 818/815/9462/6464/6711/1437/3667/1844/5604/3561/5747/3815/8844/817/84292/1439/5594/2322/409/3082/2064/5705/1438/2260/5528/7316/9978/1950/3560/2263/4233/983/3718/6714/5605/9861/6710/5519/2261/5701/5159/3558/3717/2247/8649/5698/5708/2335/2534/408/1445/5710/816/5702/1847/5979/5704/6233/2885/6709/3716/7311/5155/1956/60/4254/1843/3570/3845/3265/3559/4763/7297/5781/3569/5696/5245/7529/5156/7314/3572/28956/5595 83 Molluscum_contagiosum_virus R-HSA-450294 MAP kinase activation 35/1497 64/10654 2.2592689391517294e-14 1.9783868548247576e-13 8.16293471613854e-14 8454/3725/5601/4790/6885/5604/5594/6500/5528/7316/79155/4205/9261/5519/5598/1432/4208/23291/5602/2002/3654/7189/5609/6233/1385/2353/6196/7311/1386/5599/5600/3551/6416/7314/5595 35 Molluscum_contagiosum_virus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 30/1497 49/10654 2.597848015437709e-14 2.2596047167834033e-13 9.323255329158293e-14 1017/9134/7832/4849/1027/4869/4850/9337/1869/891/890/983/1026/6790/5111/25904/246175/1647/4848/23019/2033/995/7157/8900/10498/55571/57472/3276/85456/29883 30 Molluscum_contagiosum_virus R-HSA-2559585 Oncogene Induced Senescence 24/1497 33/10654 3.194780514688144e-14 2.7602903646905567e-13 1.1389112290958439e-13 1019/1029/57690/5594/27327/5925/192670/7316/2114/1869/6667/1871/4194/192669/7157/23112/6233/7311/4343/26523/2113/7314/5595/4193 24 Molluscum_contagiosum_virus R-HSA-73893 DNA Damage Bypass 29/1497 48/10654 1.1533038118979776e-13 9.898554570991914e-13 4.0841989295515696e-13 6118/5982/54107/9636/7706/8450/7316/9978/5425/5111/5426/7415/6119/83932/5427/1642/5985/5984/9246/6233/51426/7311/5983/6117/5981/5424/7314/51514/56655 29 Molluscum_contagiosum_virus R-HSA-2871796 FCERI mediated MAPK activation 23/1497 32/10654 1.6786385655474616e-13 1.4219056084637323e-12 5.866861997235023e-13 3725/5601/6464/2205/5335/5594/4214/2206/6850/4067/5602/5609/2885/7409/2353/3845/5599/3265/6416/5062/2207/5879/5595 23 Molluscum_contagiosum_virus R-HSA-5656169 Termination of translesion DNA synthesis 23/1497 32/10654 1.6786385655474616e-13 1.4219056084637323e-12 5.866861997235023e-13 6118/5982/54107/9636/7706/7316/5425/5111/5426/6119/5427/5985/5984/9246/6233/51426/7311/5983/6117/5981/5424/7314/56655 23 Molluscum_contagiosum_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 38/1497 78/10654 2.3091153252537705e-13 1.943255494499277e-12 8.017980760279669e-13 3665/351/7186/4790/8737/29110/57506/4214/9636/841/7706/7316/5970/4792/3146/23586/7128/1387/843/2033/64135/6288/83737/3661/9246/7189/3439/51191/6233/7311/5094/8772/5300/1540/3551/3456/4791/7314 38 Molluscum_contagiosum_virus R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 25/1497 38/10654 3.5075490084921126e-13 2.932763558068244e-12 1.2100746324713029e-12 1912/6595/6597/8535/6045/80012/1460/6598/6599/865/28996/1457/1911/84733/6604/8289/10138/2033/6605/6602/57332/861/6601/23466/6015 25 Molluscum_contagiosum_virus R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 18/1497 21/10654 3.633412098529287e-13 3.018526974162792e-12 1.245461097201672e-12 6118/2237/328/5982/54107/3978/5425/5111/5426/6119/5427/5985/5984/5983/6117/5981/5424/56655 18 Molluscum_contagiosum_virus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 78/1497 244/10654 3.9415860245217835e-13 3.253691393490593e-12 1.3424912507254887e-12 23165/23451/2963/5434/5440/5903/220988/6632/55706/7175/10946/9631/7884/11051/5430/5436/6428/3184/3178/23450/348995/79023/57122/5441/23636/5438/10762/5431/5093/23511/5435/4686/5433/53371/11338/1655/9343/3190/56339/23279/4927/9688/79902/2962/988/9883/5437/4670/23225/10189/6631/10482/3181/5439/1660/8086/1977/3187/1665/9972/6634/5094/51593/8021/9775/3192/129401/3312/10291/5432/55746/22916/56259/5725/8480/10992/6628/1994 78 Molluscum_contagiosum_virus R-HSA-446652 Interleukin-1 family signaling 54/1497 140/10654 4.2616964908319827e-13 3.4956700329862335e-12 1.442332989568719e-12 8454/3557/834/5777/351/4790/6885/5604/5783/27178/29110/3553/6500/5705/4615/7316/3565/9978/79155/6774/5970/4792/59307/3606/8809/3146/9861/3552/5701/23291/4088/5698/5708/5771/5710/6288/5702/3654/7189/5704/6233/7311/5599/5784/3551/7850/6416/5781/5696/4791/3554/7314/3596/3556 54 Molluscum_contagiosum_virus R-HSA-166520 Signaling by NTRKs 44/1497 101/10654 4.400059965848147e-13 3.586463972163018e-12 1.479795076233604e-12 5295/4908/627/6464/5290/3667/5335/4915/5604/5594/7074/5528/6774/4205/9261/6714/5605/5519/5598/1432/4208/4909/4914/2534/4803/5603/2002/2885/1385/6196/387/8851/5296/3845/5600/3265/6300/1020/5781/4916/7529/5879/5595/25920 44 Molluscum_contagiosum_virus R-HSA-191859 snRNP Assembly 30/1497 53/10654 4.845307324559703e-13 3.9003219208878105e-12 1.609294619729539e-12 23165/5903/6632/55706/7175/9631/25929/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/8086/9972/6634/8021/129401/55746/22916/8480/6628 30 Molluscum_contagiosum_virus R-HSA-194441 Metabolism of non-coding RNA 30/1497 53/10654 4.845307324559703e-13 3.9003219208878105e-12 1.609294619729539e-12 23165/5903/6632/55706/7175/9631/25929/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/8086/9972/6634/8021/129401/55746/22916/8480/6628 30 Molluscum_contagiosum_virus R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 21/1497 28/10654 4.907046406388725e-13 3.92563712511098e-12 1.6197398144544982e-12 10694/84617/10575/10382/7277/10381/7278/7203/10576/908/6950/7846/113457/347733/10574/10383/60/84790/22948/10693/7280 21 Molluscum_contagiosum_virus R-HSA-71291 Metabolism of amino acids and derivatives 104/1497 372/10654 7.810369905101907e-13 6.209962820252805e-12 2.562265361182931e-12 6158/6470/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/3620/6217/3028/6222/6176/383/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/5705/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/9861/6130/6142/6167/6204/5701/6228/23521/116832/5698/5708/445/6192/6999/140801/6156/6235/6143/5710/6181/6124/5702/26227/6207/6139/6520/10295/5704/6233/7311/6223/25873/1738/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/5696/6170/200916/6122/6133/6230 104 Molluscum_contagiosum_virus R-HSA-6803529 FGFR2 alternative splicing 20/1497 26/10654 7.929960714720144e-13 6.266603101388601e-12 2.585635457687955e-12 2963/5434/5440/5430/5436/3178/5441/5438/5431/5435/4686/5433/2962/5437/4670/5439/3187/5432/22916/5725 20 Molluscum_contagiosum_virus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 25/1497 39/10654 8.472488384678058e-13 6.649744218581651e-12 2.7437216236512986e-12 6118/5982/54107/9636/7706/7316/5425/5111/5426/7415/6119/83932/5427/5985/5984/9246/6233/51426/7311/5983/6117/5981/5424/7314/56655 25 Molluscum_contagiosum_virus R-HSA-447115 Interleukin-12 family signaling 31/1497 57/10654 8.517419292319089e-13 6.649744218581651e-12 2.7437216236512986e-12 10148/1072/3592/27250/3593/6775/3595/1265/4478/3313/6175/6774/6772/6647/149233/6950/3717/9466/3458/3181/6648/3716/3594/2939/302/51561/246778/7297/5062/3586/3572 31 Molluscum_contagiosum_virus R-HSA-5685942 HDR through Homologous Recombination (HRR) 34/1497 67/10654 9.480167448930133e-13 7.357064080127815e-12 3.035565751059886e-12 6118/5888/9156/5982/54107/545/472/11073/7316/5425/641/5111/5426/6119/3364/10524/5427/5985/84126/1111/5984/6233/51426/672/7311/5983/6117/5981/5884/5810/5424/348654/7314/56655 34 Molluscum_contagiosum_virus R-HSA-877312 Regulation of IFNG signaling 14/1497 14/10654 1.1095805659292434e-12 8.559621508597021e-12 3.5317476659903234e-12 3460/5777/5770/9021/6772/8651/3459/7341/3717/5771/3458/3716/5781/8554 14 Molluscum_contagiosum_virus R-HSA-68949 Orc1 removal from chromatin 35/1497 71/10654 1.3183871215205477e-12 1.0110234967400177e-11 4.1715394439890274e-12 8454/1017/4172/5000/23594/6500/4173/5705/7316/9978/4174/890/84515/4171/9861/4998/5701/6502/5698/5708/990/4175/5710/81620/5702/8900/5704/6233/23595/7311/5001/5696/4999/4176/7314 35 Molluscum_contagiosum_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 31/1497 58/10654 1.5855642724958008e-12 1.1809720098589412e-11 4.8727565059157105e-12 8454/8841/9734/23462/51564/55534/3280/6500/84441/10013/10046/7316/9978/9611/9759/9612/4609/10014/8850/1387/2033/55294/3066/3065/9794/6233/7311/388585/3516/4851/7314 31 Molluscum_contagiosum_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 31/1497 58/10654 1.5855642724958008e-12 1.1809720098589412e-11 4.8727565059157105e-12 8454/8841/9734/23462/51564/55534/3280/6500/84441/10013/10046/7316/9978/9611/9759/9612/4609/10014/8850/1387/2033/55294/3066/3065/9794/6233/7311/388585/3516/4851/7314 31 Molluscum_contagiosum_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 31/1497 58/10654 1.5855642724958008e-12 1.1809720098589412e-11 4.8727565059157105e-12 8454/8841/9734/23462/51564/55534/3280/6500/84441/10013/10046/7316/9978/9611/9759/9612/4609/10014/8850/1387/2033/55294/3066/3065/9794/6233/7311/388585/3516/4851/7314 31 Molluscum_contagiosum_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 31/1497 58/10654 1.5855642724958008e-12 1.1809720098589412e-11 4.8727565059157105e-12 8454/8841/9734/23462/51564/55534/3280/6500/84441/10013/10046/7316/9978/9611/9759/9612/4609/10014/8850/1387/2033/55294/3066/3065/9794/6233/7311/388585/3516/4851/7314 31 Molluscum_contagiosum_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 31/1497 58/10654 1.5855642724958008e-12 1.1809720098589412e-11 4.8727565059157105e-12 8454/8841/9734/23462/51564/55534/3280/6500/84441/10013/10046/7316/9978/9611/9759/9612/4609/10014/8850/1387/2033/55294/3066/3065/9794/6233/7311/388585/3516/4851/7314 31 Molluscum_contagiosum_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 24/1497 37/10654 1.6690618823875212e-12 1.2360595426138443e-11 5.1000507443781105e-12 1017/1029/207/11200/472/639/7316/890/983/64223/4194/5519/1616/9099/7157/8900/6233/79109/2475/7311/7874/7314/253260/4193 24 Molluscum_contagiosum_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 30/1497 55/10654 1.8014142440130831e-12 1.3264959433187248e-11 5.473196387312478e-12 834/596/351/4790/6885/842/835/29108/841/7316/5970/7128/1432/329/837/598/5603/83737/3654/7189/6233/3326/7311/64170/5600/1540/3551/6300/4791/7314 30 Molluscum_contagiosum_virus R-HSA-68882 Mitotic Anaphase 67/1497 201/10654 2.151361242087274e-12 1.569027688561625e-11 6.4738959209657705e-12 4000/5905/11130/84617/5903/10403/11065/55143/1058/991/79019/51807/10382/9212/3619/23244/7277/348995/79023/10381/57122/5705/7278/6232/332/7443/112714/1780/8881/5885/5528/7316/4085/23279/9861/79902/5519/5701/699/7846/113457/5698/347733/5708/8243/9126/10376/5710/5702/7324/2010/11004/9232/5704/6233/9700/701/7514/7311/10383/5347/84790/55746/7112/5696/7280/7314 67 Molluscum_contagiosum_virus R-HSA-5693532 DNA Double-Strand Break Repair 59/1497 166/10654 2.1549917327466766e-12 1.569027688561625e-11 6.4738959209657705e-12 1017/6118/54962/25/3838/2237/151987/5888/9156/51588/5982/63967/54107/5531/11200/545/472/3981/11073/5591/7316/890/5425/641/5111/5426/6119/3364/22976/7341/10524/5427/5985/84126/142/8914/1111/7157/8900/5984/7329/6233/51426/672/7311/6047/3980/5983/6117/5599/5981/2547/5884/5810/5424/348654/55183/7314/56655 59 Molluscum_contagiosum_virus R-HSA-69186 Lagging Strand Synthesis 17/1497 20/10654 2.2409378526175338e-12 1.6224890821186166e-11 6.694480618228211e-12 6118/2237/5982/3978/5557/5422/5425/5111/6119/5985/5984/23649/5983/6117/5981/5558/5424 17 Molluscum_contagiosum_virus R-HSA-8986944 Transcriptional Regulation by MECP2 32/1497 62/10654 2.439856100863435e-12 1.7566963926216733e-11 7.248227480927632e-12 818/27161/627/815/8841/5770/5468/817/9212/57690/27327/6657/192670/9611/28996/4233/9612/2289/5566/4988/4208/5728/816/192669/3066/3065/3654/23112/1385/25942/4343/26523 32 Molluscum_contagiosum_virus R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 16/1497 18/10654 2.4890674837112618e-12 1.782227325353478e-11 7.353569536058861e-12 5295/8805/11052/26127/5290/613/9208/6776/6774/6772/399687/2885/9846/6777/7750/1523 16 Molluscum_contagiosum_virus R-HSA-2555396 Mitotic Metaphase and Anaphase 67/1497 202/10654 2.7880447398300606e-12 1.9853329575932738e-11 8.19159472431273e-12 4000/5905/11130/84617/5903/10403/11065/55143/1058/991/79019/51807/10382/9212/3619/23244/7277/348995/79023/10381/57122/5705/7278/6232/332/7443/112714/1780/8881/5885/5528/7316/4085/23279/9861/79902/5519/5701/699/7846/113457/5698/347733/5708/8243/9126/10376/5710/5702/7324/2010/11004/9232/5704/6233/9700/701/7514/7311/10383/5347/84790/55746/7112/5696/7280/7314 67 Molluscum_contagiosum_virus R-HSA-453274 Mitotic G2-G2/M phases 66/1497 198/10654 3.1490091292704015e-12 2.2301179407292023e-11 9.201591243424585e-12 8454/1017/84617/994/2305/22981/7531/203068/54801/51807/22974/10382/3161/6500/7277/9133/10381/5705/7278/112714/7316/728642/9978/1869/891/993/890/983/1026/1639/6790/1871/9861/5566/5519/5928/5701/23291/7846/113457/5698/347733/5708/3320/2033/995/10376/10426/5710/5702/10540/7157/10733/8900/5704/6233/3326/7514/7311/10383/5347/84790/7465/5696/7280/7314 66 Molluscum_contagiosum_virus R-HSA-1980143 Signaling by NOTCH1 35/1497 73/10654 3.699413423477577e-12 2.6034899707184736e-11 1.0742145103354326e-11 8454/8841/9734/23462/51564/55534/3280/6500/409/84441/3091/10013/10046/7316/9978/9611/9759/9612/4609/10014/8850/1387/2033/408/55294/3066/3065/83737/9794/6233/7311/388585/3516/4851/7314 35 Molluscum_contagiosum_virus R-HSA-5673001 RAF/MAP kinase cascade 77/1497 249/10654 3.716401578571895e-12 2.6034899707184736e-11 1.0742145103354326e-11 818/815/9462/6464/6711/1437/3667/1844/5604/3561/5747/3815/8844/817/84292/1439/5594/2322/409/3082/2064/5705/1438/2260/5528/7316/9978/1950/3560/2263/4233/3718/6714/5605/9861/6710/5519/2261/5701/5159/3558/3717/2247/8649/5698/5708/2335/2534/408/1445/5710/816/5702/1847/5979/5704/6233/2885/6709/3716/7311/5155/1956/60/4254/1843/3845/3265/3559/4763/5696/5245/7529/5156/7314/28956/5595 77 Molluscum_contagiosum_virus R-HSA-390466 Chaperonin-mediated protein folding 41/1497 95/10654 4.024315276804236e-12 2.804039031579726e-11 1.1569621735237986e-11 2788/10694/84617/9134/8841/54331/2770/51807/10575/10382/1460/7277/10381/7278/112714/7203/10576/908/6774/1457/6950/7846/113457/347733/10376/55294/2783/2782/7157/2786/2771/10574/6468/10383/60/84790/22948/10693/7280/2773/2787 41 Molluscum_contagiosum_virus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 19/1497 25/10654 4.397316197760717e-12 3.047551760587107e-11 1.2574368862721329e-11 2308/2309/842/207/4303/84335/1027/7249/6199/1026/64223/2932/3164/79109/2475/1385/2931/253260/4193 19 Molluscum_contagiosum_virus R-HSA-180786 Extension of Telomeres 21/1497 30/10654 4.46458921515451e-12 3.0777168206597046e-11 1.2698831586217755e-11 6118/2237/5982/54107/3978/5557/5422/5425/5111/5426/6119/5427/5985/5984/23649/5983/6117/5981/5558/5424/56655 21 Molluscum_contagiosum_virus R-HSA-9022692 Regulation of MECP2 expression and activity 22/1497 33/10654 6.296231075383664e-12 4.3174155945487977e-11 1.7813898002199395e-11 818/27161/815/8841/817/9212/57690/27327/192670/9611/28996/9612/5566/816/192669/3066/3065/23112/1385/25942/4343/26523 22 Molluscum_contagiosum_virus R-HSA-6804757 Regulation of TP53 Degradation 23/1497 36/10654 7.828348349654586e-12 5.3332702551434004e-11 2.200537109822001e-11 1017/1029/207/11200/472/7316/890/983/64223/4194/5519/1616/9099/7157/8900/6233/79109/2475/7311/7874/7314/253260/4193 23 Molluscum_contagiosum_virus R-HSA-70171 Glycolysis 34/1497 71/10654 7.859989342070906e-12 5.3332702551434004e-11 2.200537109822001e-11 23165/5903/2597/55706/7175/9631/5315/5567/5568/348995/79023/57122/23636/5214/10762/23511/5528/53371/5230/23279/4927/9688/79902/5566/5519/9883/23225/2821/8086/9972/8021/129401/55746/8480 34 Molluscum_contagiosum_virus R-HSA-391251 Protein folding 42/1497 101/10654 9.725488004110228e-12 6.564704402774404e-11 2.7086337204429803e-11 2788/10694/84617/9134/8841/54331/2770/51807/10575/10382/1460/7277/10381/7278/112714/7203/10576/908/6774/1457/6950/7846/113457/347733/10376/55294/2783/2782/7157/2786/2771/10574/6468/10383/60/84790/22948/10693/7280/6904/2773/2787 42 Molluscum_contagiosum_virus R-HSA-69052 Switching of origins to a post-replicative state 39/1497 90/10654 1.1557472444155815e-11 7.760872687889086e-11 3.202179439122528e-11 8454/1017/4172/9134/5000/11065/23594/6500/4173/5705/8881/7316/9978/4174/890/84515/4171/9861/4998/5701/6502/5698/5708/990/4175/5710/81620/5702/8900/7324/5704/6233/23595/7311/5001/5696/4999/4176/7314 39 Molluscum_contagiosum_virus R-HSA-2467813 Separation of Sister Chromatids 63/1497 190/10654 1.2782348089773544e-11 8.53913563110645e-11 3.5232950784617266e-11 5905/11130/84617/5903/10403/11065/55143/1058/991/79019/51807/10382/9212/3619/23244/7277/348995/79023/10381/57122/5705/7278/6232/332/112714/1780/8881/5885/5528/7316/4085/23279/9861/79902/5519/5701/699/7846/113457/5698/347733/5708/8243/9126/10376/5710/5702/7324/11004/9232/5704/6233/9700/701/7514/7311/10383/5347/84790/55746/5696/7280/7314 63 Molluscum_contagiosum_virus R-HSA-110373 Resolution of AP sites via the multiple-nucleotide patch replacement pathway 19/1497 26/10654 1.4180470826258616e-11 9.424559072221112e-11 3.888625738050946e-11 6118/2237/328/5982/54107/3978/5425/5111/5426/6119/5427/5985/142/5984/5983/6117/5981/5424/56655 19 Molluscum_contagiosum_virus R-HSA-2500257 Resolution of Sister Chromatid Cohesion 48/1497 126/10654 1.4533988839295683e-11 9.61022935496286e-11 3.965234334243936e-11 5905/11130/84617/5903/10403/55143/1058/991/79019/51807/10382/9212/3619/23244/7277/348995/79023/9133/10381/57122/7278/6232/332/112714/1780/5885/5528/891/4085/983/23279/79902/5519/699/7846/113457/347733/8243/9126/10376/11004/701/7514/10383/5347/84790/55746/7280 48 Molluscum_contagiosum_virus R-HSA-68877 Mitotic Prometaphase 65/1497 200/10654 1.6423405978073337e-11 1.0804433577453323e-10 4.4579696697094605e-11 5905/11130/84617/5903/10403/55143/64151/22981/7531/1058/991/203068/79019/54801/51807/10382/9212/3619/1460/23244/7277/348995/79023/9133/10381/57122/7278/6232/332/112714/1780/10051/5885/5528/891/4085/1457/983/1639/23279/79902/5566/5519/699/7846/113457/347733/3320/8243/9126/10376/10426/23397/9918/10540/10733/11004/701/7514/10383/5347/84790/55746/10592/7280 65 Molluscum_contagiosum_virus R-HSA-69275 G2/M Transition 64/1497 196/10654 1.872153795372852e-11 1.2254097569713213e-10 5.056109133702333e-11 8454/1017/84617/994/2305/22981/7531/203068/54801/51807/22974/10382/3161/6500/7277/9133/10381/5705/7278/112714/7316/728642/9978/891/993/890/983/1026/1639/6790/9861/5566/5519/5928/5701/23291/7846/113457/5698/347733/5708/3320/2033/995/10376/10426/5710/5702/10540/7157/10733/8900/5704/6233/3326/7514/7311/10383/5347/84790/7465/5696/7280/7314 64 Molluscum_contagiosum_virus R-HSA-165159 mTOR signalling 24/1497 40/10654 1.921092728316559e-11 1.251123706481538e-10 5.162206326288347e-11 6194/389541/207/84335/7249/58528/6198/153129/64223/10325/8649/1981/6009/1977/10542/1975/2475/55004/10670/1978/64121/57521/7529/28956 24 Molluscum_contagiosum_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 34/1497 73/10654 2.0928283095520697e-11 1.3505125832552535e-10 5.572290385751047e-11 8454/57154/7291/10273/6500/5705/7316/9978/865/579/6772/2099/9861/2932/5701/6502/2908/5698/5708/2101/1749/55294/4488/5710/5702/5704/6233/7311/860/1750/133522/5696/10891/7314 34 Molluscum_contagiosum_virus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 42/1497 103/10654 2.0945449786597683e-11 1.3505125832552535e-10 5.572290385751047e-11 5295/5290/3667/3815/207/5594/930/3082/941/2064/2260/4615/5528/2100/1950/2263/4233/6714/2099/5519/8503/2261/5159/2247/5880/2534/3630/942/3654/7189/2885/7409/3932/5155/1956/4254/5296/5781/5156/5879/5595/3556 42 Molluscum_contagiosum_virus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 35/1497 77/10654 2.520418025974117e-11 1.6170602780507208e-10 6.672081069280102e-11 84617/51807/10382/7277/9133/10381/5705/7278/112714/7316/891/983/1026/9861/5701/7846/113457/5698/347733/5708/3320/10376/5710/5702/7157/5704/6233/3326/7311/10383/5347/84790/5696/7280/7314 35 Molluscum_contagiosum_virus R-HSA-5696400 Dual Incision in GG-NER 24/1497 41/10654 4.018638487364427e-11 2.56559383232724e-10 1.058578351869914e-10 6118/5982/54107/8450/7316/9978/5425/5111/5426/6119/5427/1642/5985/142/5984/6233/51426/7311/5983/6117/5981/5424/7314/56655 24 Molluscum_contagiosum_virus R-HSA-2559580 Oxidative Stress Induced Senescence 47/1497 125/10654 4.049110962569568e-11 2.572376376220667e-10 1.0613768673814968e-10 1912/3725/1019/5601/1029/2146/8535/6045/57690/5594/27327/80012/5931/192670/7316/1869/9261/1911/1871/4194/5928/1432/84733/5602/23512/57332/192669/7157/23135/23112/5609/6233/2353/7311/4343/8726/5599/5600/23466/4217/26523/3456/6416/7314/6015/5595/4193 47 Molluscum_contagiosum_virus R-HSA-912526 Interleukin receptor SHC signaling 19/1497 27/10654 4.155406517749633e-11 2.6270277302456215e-10 1.0839263214463741e-10 5295/5777/6464/5290/1437/3561/1439/1438/3560/3718/8503/3558/3717/3636/2885/3716/9846/5296/3559 19 Molluscum_contagiosum_virus R-HSA-5693538 Homology Directed Repair 50/1497 138/10654 4.684682014814507e-11 2.9472562578638843e-10 1.2160544013928309e-10 1017/6118/54962/25/2237/151987/5888/9156/51588/5982/63967/54107/5531/545/472/11073/7316/890/5425/641/5111/5426/6119/3364/7341/10524/5427/5985/84126/142/8914/1111/8900/5984/7329/6233/51426/672/7311/6047/3980/5983/6117/5981/5884/5810/5424/348654/7314/56655 50 Molluscum_contagiosum_virus R-HSA-8848021 Signaling by PTK6 28/1497 54/10654 5.001750603131334e-11 3.116475375797216e-10 1.2858751550560315e-10 1017/1019/5770/207/9021/55620/27043/1027/3091/2064/10657/7316/1950/5753/6774/867/6421/2908/595/6233/7311/2034/387/1956/3845/3265/7314/5879 28 Molluscum_contagiosum_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 28/1497 54/10654 5.001750603131334e-11 3.116475375797216e-10 1.2858751550560315e-10 1017/1019/5770/207/9021/55620/27043/1027/3091/2064/10657/7316/1950/5753/6774/867/6421/2908/595/6233/7311/2034/387/1956/3845/3265/7314/5879 28 Molluscum_contagiosum_virus R-HSA-176974 Unwinding of DNA 12/1497 12/10654 5.7016976624941686e-11 3.5355981677475806e-10 1.458807561091432e-10 4172/8318/9837/64785/4173/4174/84515/4171/4175/84296/51659/4176 12 Molluscum_contagiosum_virus R-HSA-199418 Negative regulation of the PI3K/AKT network 43/1497 110/10654 6.28990421065423e-11 3.881769455718039e-10 1.6016397689284956e-10 5295/5290/3667/3815/207/5594/930/3082/941/2064/2260/4615/5528/2100/1950/2263/4233/6714/2099/5519/8503/2261/5159/2247/5880/2534/5728/3630/942/3654/7189/2885/7409/3932/5155/1956/4254/5296/5781/5156/5879/5595/3556 43 Molluscum_contagiosum_virus R-HSA-9006115 Signaling by NTRK2 (TRKB) 18/1497 25/10654 7.470505828451128e-11 4.5885192197500765e-10 1.893248670917023e-10 5295/4908/627/6464/5290/5335/4915/7074/6714/4909/2534/2885/8851/3845/3265/1020/5781/5879 18 Molluscum_contagiosum_virus R-HSA-168638 NOD1/2 Signaling Pathway 22/1497 36/10654 8.067018783232653e-11 4.931536010881848e-10 2.0347793157309772e-10 834/6885/842/835/841/7316/7128/1432/329/837/5603/83737/3654/7189/6233/7311/64170/5600/1540/3551/6300/7314 22 Molluscum_contagiosum_virus R-HSA-5663220 RHO GTPases Activate Formins 50/1497 140/10654 8.536937650582366e-11 5.194305725424763e-10 2.1431995683201591e-10 5905/11130/84617/5903/10403/55143/1058/991/79019/51807/10382/9212/3619/388/7277/348995/79023/10381/57122/7278/6232/332/112714/1780/5528/3688/4085/6714/23279/79902/5519/699/7846/113457/347733/10376/11004/1855/701/1857/7514/23380/10383/5347/387/60/84790/55746/7280/5879 50 Molluscum_contagiosum_virus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 36/1497 84/10654 1.0510154152847596e-10 6.365027935556301e-10 2.62624609426787e-10 9318/6118/83444/5982/54107/3978/8450/7316/9978/5425/5111/5426/10980/6119/7341/10401/5427/1642/5985/142/10987/5984/7329/6233/51426/7311/3980/60/5983/6117/5981/5424/7314/8554/7528/56655 36 Molluscum_contagiosum_virus R-HSA-350054 Notch-HLH transcription pathway 19/1497 28/10654 1.1225351414318933e-10 6.766537410677831e-10 2.7919111473557005e-10 8841/9734/51564/55534/84441/10013/10046/4854/9611/9759/9612/10014/8850/1387/3066/3065/9794/3516/4851 19 Molluscum_contagiosum_virus R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 17/1497 23/10654 1.3012941145519537e-10 7.807764687311722e-10 3.221527340118872e-10 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/5439/5432/22916/25920 17 Molluscum_contagiosum_virus R-HSA-388841 Costimulation by the CD28 family 32/1497 70/10654 1.498082463910619e-10 8.947073148516876e-10 3.6916123777181395e-10 5295/5777/5290/207/941/919/5528/920/6714/64223/5519/8503/29126/4067/915/917/2534/1445/916/942/2885/7525/79109/2475/7409/3932/5296/3127/5781/5062/5879/253260 32 Molluscum_contagiosum_virus R-HSA-5621481 C-type lectin receptors (CLRs) 50/1497 142/10654 1.5314277796803122e-10 9.104267901218736e-10 3.7564718110941504e-10 8454/4773/4790/6885/4772/5567/3553/5532/5568/4775/4582/6500/29108/5705/841/5530/7316/5970/4792/6850/6714/9861/5566/5701/1387/4067/23291/5698/5708/2534/2033/5710/5702/9040/7189/5704/6233/5580/7311/5971/64170/3845/3265/3551/5062/5696/997/2207/4791/7314 50 Molluscum_contagiosum_virus R-HSA-5655253 Signaling by FGFR2 in disease 24/1497 43/10654 1.5966265717254855e-10 9.4485298491152e-10 3.8985162145472086e-10 5295/2963/5434/5440/5290/5335/5430/5436/5441/5438/5431/5435/4686/5433/2263/2962/5437/2247/5439/2885/3845/3265/5432/22916 24 Molluscum_contagiosum_virus R-HSA-109581 Apoptosis 58/1497 178/10654 1.8264363790669674e-10 1.075937066941268e-9 4.439376462038371e-10 4000/3837/596/7186/1499/10018/7531/5747/1029/842/8737/356/207/5594/63967/5705/841/7099/100506658/9500/7316/1869/6774/54205/660/3146/9861/5701/329/999/598/836/5698/5708/5710/5702/7157/3836/5704/6233/5580/6709/7311/7161/839/840/1630/8772/5599/8717/7431/8795/5062/6304/5696/7529/7314/5595 58 Molluscum_contagiosum_virus R-HSA-68867 Assembly of the pre-replicative complex 31/1497 68/10654 3.1639713338391616e-10 1.855432963192558e-9 7.655620088546293e-10 4172/5000/23594/4173/5705/7316/1869/4174/84515/4171/1871/9861/51053/4998/5701/5698/5708/990/4175/5710/81620/5702/5704/6233/23595/7311/5001/5696/4999/4176/7314 31 Molluscum_contagiosum_virus R-HSA-110320 Translesion Synthesis by POLH 15/1497 19/10654 3.4263689160738323e-10 1.982399158585574e-9 8.179489705664977e-10 6118/5982/7316/5111/7415/6119/83932/5985/5984/6233/7311/5983/6117/5981/7314 15 Molluscum_contagiosum_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 15/1497 19/10654 3.4263689160738323e-10 1.982399158585574e-9 8.179489705664977e-10 5295/6464/5290/5335/7316/1950/867/3320/6233/2885/7311/1956/3845/3265/7314 15 Molluscum_contagiosum_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 15/1497 19/10654 3.4263689160738323e-10 1.982399158585574e-9 8.179489705664977e-10 5295/6464/5290/5335/7316/1950/867/3320/6233/2885/7311/1956/3845/3265/7314 15 Molluscum_contagiosum_virus R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 47/1497 132/10654 3.534875313658538e-10 2.036088180667318e-9 8.401013610940526e-10 1017/6118/54962/25/151987/5888/9156/51588/5982/63967/54107/5531/545/472/11073/7316/890/5425/641/5111/5426/6119/3364/7341/10524/5427/5985/84126/8914/1111/8900/5984/7329/6233/51426/672/7311/6047/5983/6117/5981/5884/5810/5424/348654/7314/56655 47 Molluscum_contagiosum_virus R-HSA-4420097 VEGFA-VEGFR2 Pathway 39/1497 99/10654 3.718837637632611e-10 2.132572379810559e-9 8.799112808185219e-10 5295/26999/5290/5335/1499/5747/5567/207/7422/5568/3315/9047/9261/6714/64223/5566/1432/3320/2534/4846/5603/79109/5580/2475/7409/23191/3685/3791/387/60/5296/3845/5600/3265/6300/5062/10787/5879/253260 39 Molluscum_contagiosum_virus R-HSA-5357801 Programmed Cell Death 58/1497 181/10654 3.8103578658472084e-10 2.1754289842017543e-9 8.975941552749277e-10 4000/3837/596/7186/1499/10018/7531/5747/1029/842/8737/356/207/5594/63967/5705/841/7099/100506658/9500/7316/1869/6774/54205/660/3146/9861/5701/329/999/598/836/5698/5708/5710/5702/7157/3836/5704/6233/5580/6709/7311/7161/839/840/1630/8772/5599/8717/7431/8795/5062/6304/5696/7529/7314/5595 58 Molluscum_contagiosum_virus R-HSA-203927 MicroRNA (miRNA) biogenesis 17/1497 24/10654 3.8766952103282976e-10 2.193972485845185e-9 9.052453076749139e-10 27161/5434/5440/5430/5436/5441/192670/5438/5431/5435/5433/5437/5439/192669/26523/5432/23405 17 Molluscum_contagiosum_virus R-HSA-6783589 Interleukin-6 family signaling 17/1497 24/10654 3.8766952103282976e-10 2.193972485845185e-9 9.052453076749139e-10 3589/9021/3976/6774/6772/867/3717/3716/1270/3570/5008/3977/7297/5781/3569/1489/3572 17 Molluscum_contagiosum_virus R-HSA-1059683 Interleukin-6 signaling 11/1497 11/10654 4.083658695957308e-10 2.3010528999829007e-9 9.494272849182209e-10 9021/6774/6772/867/3717/3716/3570/7297/5781/3569/3572 11 Molluscum_contagiosum_virus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 30/1497 65/10654 4.2032672637649655e-10 2.3581966986317727e-9 9.730051355628175e-10 2176/3725/2963/5434/5440/4436/5430/5436/6749/545/472/5441/5438/5431/5435/5433/2962/5437/2177/5439/1111/7157/55215/672/1025/2353/1386/11198/5432/25920 30 Molluscum_contagiosum_virus R-HSA-5655862 Translesion synthesis by POLK 14/1497 17/10654 4.968301456254919e-10 2.7634844151529506e-9 1.1402291121651226e-9 6118/5982/7316/5111/6119/5985/5984/6233/51426/7311/5983/6117/5981/7314 14 Molluscum_contagiosum_virus R-HSA-8934593 Regulation of RUNX1 Expression and Activity 14/1497 17/10654 4.968301456254919e-10 2.7634844151529506e-9 1.1402291121651226e-9 27161/57690/27327/192670/865/6714/595/192669/861/5371/23112/4343/26523/5781 14 Molluscum_contagiosum_virus R-HSA-1170546 Prolactin receptor signaling 13/1497 15/10654 6.331094680129859e-10 3.506452438225768e-9 1.4467818702231079e-9 8454/2690/6500/6776/9978/1442/3717/5618/2688/5617/6777/2689/5781 13 Molluscum_contagiosum_virus R-HSA-5357786 TNFR1-induced proapoptotic signaling 12/1497 13/10654 6.457459241399847e-10 3.561220075257107e-9 1.4693793033062137e-9 7124/7186/8737/7375/841/27005/7128/7132/9099/8772/8717/1540 12 Molluscum_contagiosum_virus R-HSA-4090294 SUMOylation of intracellular receptors 19/1497 30/10654 6.694764793945466e-10 3.6764471071836115e-9 1.5169226205728352e-9 6095/5241/5468/51588/2516/5465/9759/2099/7341/10401/2908/6256/7329/7376/367/9063/7421/10062/8554 19 Molluscum_contagiosum_virus R-HSA-113510 E2F mediated regulation of DNA replication 16/1497 22/10654 6.927739916283715e-10 3.772416357774662e-9 1.5565200696471153e-9 5000/23594/5925/5557/5422/1869/891/983/84515/5519/4998/23595/23649/5001/5558/4999 16 Molluscum_contagiosum_virus R-HSA-912631 Regulation of signaling by CBL 16/1497 22/10654 6.927739916283715e-10 3.772416357774662e-9 1.5565200696471153e-9 5295/5290/7316/3055/6850/8503/867/4067/2534/6233/2885/7525/7409/7311/5296/7314 16 Molluscum_contagiosum_virus R-HSA-73933 Resolution of Abasic Sites (AP sites) 22/1497 39/10654 7.084158202101328e-10 3.841451476955365e-9 1.5850043455923695e-9 6118/2237/328/5982/54107/3978/6996/5425/5111/5426/6119/5427/5985/142/5984/3980/5983/6117/5981/5424/7374/56655 22 Molluscum_contagiosum_virus R-HSA-389356 CD28 co-stimulation 20/1497 33/10654 7.331673605357257e-10 3.959103746892919e-9 1.633548329614687e-9 5295/5290/207/941/6714/64223/8503/4067/2534/942/2885/7525/79109/2475/7409/3932/5296/5062/5879/253260 20 Molluscum_contagiosum_virus R-HSA-5687128 MAPK6/MAPK4 signaling 36/1497 89/10654 7.423724906911269e-10 3.992177377326558e-9 1.647194694348515e-9 2308/27161/2118/3725/2309/5567/57690/5568/3315/27327/5705/192670/7316/983/5597/4609/9861/5566/5701/5698/5708/5710/5702/192669/23112/5704/6233/7514/7311/4343/26523/8202/5062/5696/7314/5879 36 Molluscum_contagiosum_virus R-HSA-429914 Deadenylation-dependent mRNA decay 27/1497 56/10654 9.305523158728496e-10 4.983453724674434e-9 2.0562008545602768e-9 1656/9924/80153/5073/27257/4849/4850/255967/26986/10605/9337/25904/246175/4848/23019/1981/1973/1977/1975/55571/9775/54464/57472/85456/29883/1974/167227 27 Molluscum_contagiosum_virus R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 32/1497 75/10654 1.3135005813177165e-9 7.005336433694488e-9 2.890440958671865e-9 5295/5290/3667/3815/930/3082/941/2064/2260/2100/1950/2263/4233/6714/2099/8503/2261/5159/2247/5880/2534/942/2885/7409/3932/5155/1956/4254/5296/5781/5156/5879 32 Molluscum_contagiosum_virus R-HSA-983231 Factors involved in megakaryocyte development and platelet production 54/1497 168/10654 1.3582167676390187e-9 7.214134962541673e-9 2.976592398449618e-9 55582/1017/84617/25/2624/23186/5567/51807/23095/10382/2625/5568/29127/3832/7277/10381/7278/112714/23303/285643/3659/5566/23414/10112/3705/3717/7846/5576/113457/347733/10376/3066/3065/7157/23028/3439/11004/10749/10383/24137/51317/60/25942/84790/9493/7465/3456/1020/81704/10603/7280/3660/9732/5879 54 Molluscum_contagiosum_virus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 19/1497 31/10654 1.5019464980957842e-9 7.94499045523321e-9 3.2781474587869323e-9 3725/5601/5594/5528/4205/9261/5519/5598/1432/4208/5602/2002/1385/2353/6196/1386/5599/5600/5595 19 Molluscum_contagiosum_virus R-HSA-190840 Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane 14/1497 18/10654 1.94541010122882e-9 1.0248989801595735e-8 4.228790463946259e-9 84617/51807/10382/7277/10381/7278/112714/7846/113457/347733/10376/10383/84790/7280 14 Molluscum_contagiosum_virus R-HSA-187037 Signaling by NTRK1 (TRKA) 33/1497 80/10654 2.0795296030454284e-9 1.0911216054845648e-8 4.502028716586736e-9 5295/6464/5290/3667/5335/4915/5604/5594/5528/6774/4205/9261/6714/5605/5519/5598/1432/4208/4914/4803/5603/2002/2885/1385/6196/387/5296/3845/5600/3265/6300/7529/5595 33 Molluscum_contagiosum_virus R-HSA-9614085 FOXO-mediated transcription 29/1497 65/10654 2.206738572335424e-9 1.1531988668333505e-8 4.758162965816619e-9 2308/2309/65018/10018/356/207/4303/1027/1649/4800/5443/1026/4089/8850/1647/1387/4088/2908/2033/3630/3066/3065/6648/4087/604/23411/25942/7529/10891 29 Molluscum_contagiosum_virus R-HSA-5655302 Signaling by FGFR1 in disease 21/1497 38/10654 2.8916824591477722e-9 1.4883326760080274e-8 6.140943789896669e-9 5295/8805/11052/26127/5290/5335/613/2260/9208/6776/6774/6772/399687/2247/2885/9846/3845/6777/3265/7750/1523 21 Molluscum_contagiosum_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 38/1497 101/10654 2.916415157418594e-9 1.4883326760080274e-8 6.140943789896669e-9 8454/4773/4790/6885/4772/3553/5532/4775/6500/29108/5705/841/5530/7316/5970/4792/6850/6714/9861/5701/23291/5698/5708/5710/5702/9040/7189/5704/6233/5580/7311/5971/64170/3551/5696/997/4791/7314 38 Molluscum_contagiosum_virus R-HSA-110056 MAPK3 (ERK1) activation 10/1497 10/10654 2.923097724261568e-9 1.4883326760080274e-8 6.140943789896669e-9 5604/983/3717/3716/3570/7297/5781/3569/3572/5595 10 Molluscum_contagiosum_virus R-HSA-390450 Folding of actin by CCT/TriC 10/1497 10/10654 2.923097724261568e-9 1.4883326760080274e-8 6.140943789896669e-9 10694/10575/7203/10576/908/6950/10574/60/22948/10693 10 Molluscum_contagiosum_virus R-HSA-450341 Activation of the AP-1 family of transcription factors 10/1497 10/10654 2.923097724261568e-9 1.4883326760080274e-8 6.140943789896669e-9 3725/5601/5594/1432/5602/2353/1386/5599/5600/5595 10 Molluscum_contagiosum_virus R-HSA-9020958 Interleukin-21 signaling 10/1497 10/10654 2.923097724261568e-9 1.4883326760080274e-8 6.140943789896669e-9 3561/6775/6776/50615/6774/3718/6772/3716/6777/59067 10 Molluscum_contagiosum_virus R-HSA-110312 Translesion synthesis by REV1 13/1497 16/10654 2.9399163970528936e-9 1.4883326760080274e-8 6.140943789896669e-9 6118/5982/7316/5111/6119/5985/5984/6233/7311/5983/6117/5981/7314 13 Molluscum_contagiosum_virus R-HSA-1433559 Regulation of KIT signaling 13/1497 16/10654 2.9399163970528936e-9 1.4883326760080274e-8 6.140943789896669e-9 5777/3815/9306/6714/8651/867/4067/2534/2885/7525/3932/4254/10603 13 Molluscum_contagiosum_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 34/1497 85/10654 3.1096177737378957e-9 1.568118534927748e-8 6.4701447022684866e-9 8454/1017/9134/1019/994/207/1027/6500/5925/5705/4149/7316/1869/5753/993/890/1026/4609/9861/5928/5701/6502/5698/5708/595/5710/5702/8900/5704/6233/7311/7465/5696/7314 34 Molluscum_contagiosum_virus R-HSA-8941326 RUNX2 regulates bone development 19/1497 32/10654 3.210873340083846e-9 1.6129038173444436e-8 6.654931280141142e-9 25/8841/23462/5594/3280/4086/5925/10013/865/4094/9759/10413/6714/4089/23314/7525/367/860/5595 19 Molluscum_contagiosum_virus R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 26/1497 55/10654 3.2564015523752823e-9 1.629458074084311e-8 6.723235068509017e-9 84617/5241/51807/10382/7277/10381/7278/112714/1780/1639/2289/7846/113457/2908/347733/3320/10376/10540/3326/367/10383/84790/3312/7280/2288/10728 26 Molluscum_contagiosum_virus R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 15/1497 21/10654 3.628382960540744e-9 1.808609352638771e-8 7.462423254877321e-9 7832/4849/4869/4850/9337/25904/246175/4848/23019/995/7157/55571/57472/85456/29883 15 Molluscum_contagiosum_virus R-HSA-211000 Gene Silencing by RNA 46/1497 136/10654 3.675432417428162e-9 1.8250423038263976e-8 7.53022652975804e-9 23165/27161/5434/5440/5903/55706/7175/9631/5430/5436/57690/27327/348995/79023/57122/5441/23636/192670/5438/10762/5431/23511/5435/5433/53371/23279/4927/9688/79902/9883/5437/23225/3320/5439/192669/8086/23112/9972/8021/7257/129401/26523/5432/55746/23405/8480 46 Molluscum_contagiosum_virus R-HSA-5578749 Transcriptional regulation by small RNAs 39/1497 106/10654 3.8180058222931015e-9 1.888601353317504e-8 7.792474719666115e-9 23165/27161/5434/5440/5903/55706/7175/9631/5430/5436/27327/348995/79023/57122/5441/23636/5438/10762/5431/23511/5435/5433/53371/23279/4927/9688/79902/9883/5437/23225/5439/8086/9972/8021/129401/26523/5432/55746/8480 39 Molluscum_contagiosum_virus R-HSA-174411 Polymerase switching on the C-strand of the telomere 12/1497 14/10654 3.938445349232575e-9 1.918881643836623e-8 7.917412890424013e-9 5982/5557/5422/5425/5111/5985/5984/23649/5983/5981/5558/5424 12 Molluscum_contagiosum_virus R-HSA-69091 Polymerase switching 12/1497 14/10654 3.938445349232575e-9 1.918881643836623e-8 7.917412890424013e-9 5982/5557/5422/5425/5111/5985/5984/23649/5983/5981/5558/5424 12 Molluscum_contagiosum_virus R-HSA-69109 Leading Strand Synthesis 12/1497 14/10654 3.938445349232575e-9 1.918881643836623e-8 7.917412890424013e-9 5982/5557/5422/5425/5111/5985/5984/23649/5983/5981/5558/5424 12 Molluscum_contagiosum_virus R-HSA-8983432 Interleukin-15 signaling 12/1497 14/10654 3.938445349232575e-9 1.918881643836623e-8 7.917412890424013e-9 6464/3561/6776/3560/6774/3718/2885/3716/9846/6777/3600/3601 12 Molluscum_contagiosum_virus R-HSA-3371511 HSF1 activation 11/1497 12/10654 4.273203692274398e-9 2.0587628197723496e-8 8.494570438956737e-9 6118/7531/1915/10013/7415/6119/3320/3326/6117/3297/10728 11 Molluscum_contagiosum_virus R-HSA-8984722 Interleukin-35 Signalling 11/1497 12/10654 4.273203692274398e-9 2.0587628197723496e-8 8.494570438956737e-9 10148/3592/6775/3595/6774/6772/3717/9466/3716/7297/3572 11 Molluscum_contagiosum_virus R-HSA-9020558 Interleukin-2 signaling 11/1497 12/10654 4.273203692274398e-9 2.0587628197723496e-8 8.494570438956737e-9 6464/3561/6776/3560/6850/3718/3558/3716/3932/6777/3559 11 Molluscum_contagiosum_virus R-HSA-157118 Signaling by NOTCH 67/1497 235/10654 4.293196257288559e-9 2.0607342034985085e-8 8.502704478372663e-9 8454/27161/3725/8841/2208/9734/23462/207/51564/55534/57690/3280/6500/27327/409/84441/3091/10013/5705/10046/192670/7316/9978/1950/1869/4854/9611/9759/9612/6772/4609/1871/9861/10014/8850/5701/1387/4088/5698/5708/2033/408/595/55294/5710/5702/192669/3066/3065/7157/83737/861/23112/9794/5704/6233/1385/7311/1956/4343/9787/388585/26523/3516/4851/5696/7314 67 Molluscum_contagiosum_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 28/1497 63/10654 4.6416613228439375e-9 2.2197760422161414e-8 9.158919992249838e-9 3665/5434/5440/4790/1499/8737/29110/5441/6778/4615/7098/9208/5591/5435/7316/5970/4792/1387/5437/2033/1660/3661/6233/7311/3551/2547/4791/7314 28 Molluscum_contagiosum_virus R-HSA-3371571 HSF1-dependent transactivation 16/1497 24/10654 5.161117196864074e-9 2.4501127791706373e-8 1.010930224024272e-8 818/815/817/84335/64223/1387/3320/2033/816/3326/2475/3312/3297/57521/2288/10728 16 Molluscum_contagiosum_virus R-HSA-8940973 RUNX2 regulates osteoblast differentiation 16/1497 24/10654 5.161117196864074e-9 2.4501127791706373e-8 1.010930224024272e-8 25/8841/23462/5594/3280/5925/10013/865/4094/10413/6714/23314/7525/367/860/5595 16 Molluscum_contagiosum_virus R-HSA-194138 Signaling by VEGF 39/1497 107/10654 5.205152543579336e-9 2.4619991592988396e-8 1.0158346108867856e-8 5295/26999/5290/5335/1499/5747/5567/207/7422/5568/3315/9047/9261/6714/64223/5566/1432/3320/2534/4846/5603/79109/5580/2475/7409/23191/3685/3791/387/60/5296/3845/5600/3265/6300/5062/10787/5879/253260 39 Molluscum_contagiosum_virus R-HSA-9020702 Interleukin-1 signaling 38/1497 103/10654 5.529362710400061e-9 2.605837844610356e-8 1.0751832562232464e-8 8454/3557/351/4790/6885/5604/3553/6500/5705/4615/7316/9978/79155/5970/4792/3146/9861/3552/5701/23291/5698/5708/5710/6288/5702/3654/7189/5704/6233/7311/3551/7850/6416/5696/4791/3554/7314/3556 38 Molluscum_contagiosum_virus R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 31/1497 75/10654 6.025170265542565e-9 2.8292103855591175e-8 1.1673480148343337e-8 23165/5903/55706/7175/9631/6428/348995/79023/57122/23636/10762/23511/4686/53371/11338/23279/4927/9688/79902/9883/23225/10189/10482/8086/9972/8021/9775/129401/55746/22916/8480 31 Molluscum_contagiosum_virus R-HSA-69202 Cyclin E associated events during G1/S transition 33/1497 83/10654 6.346683649571784e-9 2.969423108247304e-8 1.2252005677303692e-8 8454/1017/9134/1019/207/1027/6500/5925/5705/4149/7316/1869/5753/993/890/1026/4609/9861/5928/5701/6502/5698/5708/595/5710/5702/8900/5704/6233/7311/7465/5696/7314 33 Molluscum_contagiosum_virus R-HSA-190872 Transport of connexons to the plasma membrane 14/1497 19/10654 6.433175088168839e-9 2.999062918801013e-8 1.2374301191934004e-8 84617/51807/10382/7277/10381/7278/112714/7846/113457/347733/10376/10383/84790/7280 14 Molluscum_contagiosum_virus R-HSA-1227986 Signaling by ERBB2 24/1497 50/10654 8.96566414354066e-9 4.164695602160823e-8 1.7183766779545953e-8 5295/6464/5290/5335/10273/207/2064/7316/1950/5753/6714/3320/2534/6233/2885/7525/5580/7311/387/1956/5581/3845/3265/7314 24 Molluscum_contagiosum_virus R-HSA-72202 Transport of Mature Transcript to Cytoplasm 33/1497 84/10654 9.060303524286715e-9 4.1936262026698515e-8 1.7303136053900945e-8 23165/5903/55706/7175/9631/7884/6428/348995/79023/57122/23636/10762/23511/4686/53371/11338/23279/4927/9688/79902/9883/23225/10189/10482/8086/1977/9972/8021/9775/129401/55746/22916/8480 33 Molluscum_contagiosum_virus R-HSA-389977 Post-chaperonin tubulin folding pathway 15/1497 22/10654 9.918973608210169e-9 4.542399221286352e-8 1.8742193018303017e-8 84617/51807/10382/7277/10381/7278/112714/7846/113457/347733/10376/10383/84790/7280/6904 15 Molluscum_contagiosum_virus R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 15/1497 22/10654 9.918973608210169e-9 4.542399221286352e-8 1.8742193018303017e-8 4000/3725/826/351/994/2309/10018/7531/356/823/993/995/6648/8851/1020 15 Molluscum_contagiosum_virus R-HSA-8863678 Neurodegenerative Diseases 15/1497 22/10654 9.918973608210169e-9 4.542399221286352e-8 1.8742193018303017e-8 4000/3725/826/351/994/2309/10018/7531/356/823/993/995/6648/8851/1020 15 Molluscum_contagiosum_virus R-HSA-5656121 Translesion synthesis by POLI 13/1497 17/10654 1.0879946714191913e-8 4.964933430138282e-8 2.048559277542436e-8 6118/5982/7316/5111/6119/5985/5984/6233/7311/5983/6117/5981/7314 13 Molluscum_contagiosum_virus R-HSA-9020591 Interleukin-12 signaling 23/1497 47/10654 1.1455284020848869e-8 5.2091396810596965e-8 2.1493201413079318e-8 1072/3592/27250/3593/6775/3595/1265/4478/3313/6175/6647/6950/3717/3458/3181/6648/3716/3594/2939/302/7297/5062/3586 23 Molluscum_contagiosum_virus R-HSA-5685938 HDR through Single Strand Annealing (SSA) 20/1497 37/10654 1.1563754786023146e-8 5.2400790918482505e-8 2.1620859150900842e-8 6118/25/5888/9156/5982/545/472/11073/641/6119/3364/10524/5985/84126/5984/672/5983/6117/5884/5810 20 Molluscum_contagiosum_virus R-HSA-1839124 FGFR1 mutant receptor activation 18/1497 31/10654 1.3776408866208762e-8 6.220984630873365e-8 2.566813021835339e-8 5295/8805/11052/26127/5290/613/2260/9208/6776/6774/6772/399687/2247/2885/9846/6777/7750/1523 18 Molluscum_contagiosum_virus R-HSA-76002 Platelet activation, signaling and aggregation 71/1497 262/10654 1.5443945116313183e-8 6.949775302340933e-8 2.8675161253973312e-8 5295/2788/928/5777/351/1072/6464/5321/5290/54331/7018/5770/7042/5747/2770/2316/207/7422/5594/409/3082/388/7277/83706/334/1950/335/308/6850/2767/6714/6647/8503/4352/1432/4067/81/5880/2335/2534/408/2783/1445/2782/87/2786/2771/10487/2885/5580/7409/3932/7076/3479/5155/387/5296/5581/51368/7040/213/5781/7043/2207/2773/967/5879/5595/2787/7066/10672 71 Molluscum_contagiosum_virus R-HSA-69183 Processive synthesis on the lagging strand 12/1497 15/10654 1.7159788874110994e-8 7.695185598909291e-8 3.175076579147108e-8 6118/2237/3978/5557/5422/5425/5111/6119/23649/6117/5558/5424 12 Molluscum_contagiosum_virus R-HSA-5628897 TP53 Regulates Metabolic Genes 33/1497 86/10654 1.8054251466432958e-8 8.06838272430935e-8 3.329059798529199e-8 27161/7531/389541/207/57690/7249/27327/58528/192670/153129/54205/64223/10325/2821/8649/10128/5728/6009/192669/7157/23112/10542/2475/55004/10670/4513/4343/50484/26523/64121/57521/7529/28956 33 Molluscum_contagiosum_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 39/1497 112/10654 2.2701118052994193e-8 1.0110188658653085e-7 4.171520336741202e-8 5295/8454/5777/4773/4790/6885/5966/4772/640/5532/4775/6500/930/5705/5530/7316/5970/4792/6850/9861/5701/4067/23291/5698/5708/2534/5710/5702/695/5704/6233/2885/7409/7311/3845/3265/3551/5696/7314 39 Molluscum_contagiosum_virus R-HSA-383280 Nuclear Receptor transcription pathway 24/1497 52/10654 2.3677652022004957e-8 1.0508985280999461e-7 4.336066051614462e-8 6095/5241/7182/5468/3172/2516/6097/5465/2100/9611/5469/2063/9612/2099/7101/5467/2908/3164/2101/6256/7376/367/7421/10062 24 Molluscum_contagiosum_virus R-HSA-70326 Glucose metabolism 34/1497 91/10654 2.4206856764319386e-8 1.0678432298112164e-7 4.405980837752584e-8 23165/5903/2597/55706/7175/9631/5315/5567/5568/348995/79023/57122/23636/5214/10762/23511/5528/53371/5230/23279/4927/9688/79902/5566/5519/9883/23225/2821/8086/9972/8021/129401/55746/8480 34 Molluscum_contagiosum_virus R-HSA-209560 NF-kB is activated and signals survival 11/1497 13/10654 2.422422141701371e-8 1.0678432298112164e-7 4.405980837752584e-8 4790/7316/5970/4792/4803/3654/7189/6233/7311/3551/7314 11 Molluscum_contagiosum_virus R-HSA-112409 RAF-independent MAPK1/3 activation 15/1497 23/10654 2.4806763974273207e-8 1.0898158003612907e-7 4.4966408916791396e-8 1844/5604/5594/983/5605/3717/1847/3716/1843/3570/7297/5781/3569/3572/5595 15 Molluscum_contagiosum_virus R-HSA-5626467 RHO GTPases activate IQGAPs 18/1497 32/10654 2.736066882836936e-8 1.1979536081610368e-7 4.9428235294493725e-8 84617/1499/51807/10382/7277/10381/7278/112714/7846/999/113457/347733/10376/10383/60/84790/7280/5879 18 Molluscum_contagiosum_virus R-HSA-2514853 Condensation of Prometaphase Chromosomes 10/1497 11/10654 2.8070416270920033e-8 1.2207805197017572e-7 5.037008642044288e-8 64151/1460/9133/10051/891/1457/983/23397/9918/10592 10 Molluscum_contagiosum_virus R-HSA-68689 CDC6 association with the ORC:origin complex 10/1497 11/10654 2.8070416270920033e-8 1.2207805197017572e-7 5.037008642044288e-8 5000/23594/1869/84515/1871/4998/990/23595/5001/4999 10 Molluscum_contagiosum_virus R-HSA-186763 Downstream signal transduction 17/1497 29/10654 2.8819099591238394e-8 1.2449851023414987e-007 5.136878102578634e-8 5295/5290/5335/6778/6776/6774/6772/6714/5159/2885/5155/5296/3845/6777/3265/5781/5156 17 Molluscum_contagiosum_virus R-HSA-72086 mRNA Capping 17/1497 29/10654 2.8819099591238394e-8 1.2449851023414987e-007 5.136878102578634e-8 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/8731/2962/5437/5439/5432/22916 17 Molluscum_contagiosum_virus R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 20/1497 39/10654 3.778945789796511e-8 1.6270809779323183e-7 6.713427036952711e-8 6118/5888/9156/5982/545/472/11073/641/6119/3364/10524/5985/84126/1111/5984/672/5983/6117/5884/5810 20 Molluscum_contagiosum_virus R-HSA-6784531 tRNA processing in the nucleus 25/1497 57/10654 4.303878196764268e-8 1.846962299008772e-7 7.620669654779534e-8 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/283742/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 25 Molluscum_contagiosum_virus R-HSA-1266695 Interleukin-7 signaling 19/1497 36/10654 4.523650170276089e-8 1.934868191642842e-7 7.983374280007829e-8 5295/54014/3667/6597/64109/3561/3082/6776/6774/3718/8651/8503/3716/85480/1154/3575/5296/8835/6777 19 Molluscum_contagiosum_virus R-HSA-438064 Post NMDA receptor activation events 31/1497 81/10654 5.223754566924285e-8 2.2225466135381862e-7 9.170351524345343e-8 818/84617/815/3838/5567/51807/817/10382/5594/5568/7277/10381/7278/112714/6714/5566/7846/5576/113457/347733/10376/816/1385/6196/10383/84790/3845/3265/7280/5879/5595 31 Molluscum_contagiosum_virus R-HSA-1839126 FGFR2 mutant receptor activation 18/1497 33/10654 5.2305302247619356e-8 2.2225466135381862e-7 9.170351524345343e-8 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2263/2962/5437/2247/5439/5432/22916 18 Molluscum_contagiosum_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 29/1497 73/10654 5.3470226830454105e-8 2.2646213716427622e-7 9.343954327440897e-8 57154/6497/10273/51592/3726/50848/7316/9611/9612/6667/4609/4089/867/7050/4088/142/3065/9958/9040/4087/6233/7514/7048/1025/7311/387/7040/57530/7314 29 Molluscum_contagiosum_virus R-HSA-195258 RHO GTPase Effectors 82/1497 327/10654 5.4799250322636564e-8 2.313349459874169e-7 9.545009142430784e-8 26999/5905/11130/84617/25/5903/1072/10403/51517/55143/1499/7531/5747/1058/991/79019/51807/2316/10382/9212/5594/1027/3619/388/1080/7277/348995/79023/10381/57122/7278/6232/332/112714/1780/6242/5528/3688/4085/5585/6714/23279/79902/5519/1432/2017/699/7846/999/113457/347733/5880/995/10376/23028/695/11004/1855/2885/5580/701/1857/9055/23191/7514/23380/57120/367/10383/5347/387/60/5300/84790/5600/5062/55746/7280/7529/10787/5879/5595 82 Molluscum_contagiosum_virus R-HSA-5693607 Processing of DNA double-strand break ends 35/1497 98/10654 5.7303356813498696e-8 2.411206182801763e-7 9.948771449506953e-8 1017/6118/54962/151987/9156/51588/5982/63967/5531/545/472/11073/7316/890/641/6119/3364/7341/10524/5985/84126/8914/1111/8900/5984/7329/6233/672/7311/6047/5983/6117/5884/5810/7314 35 Molluscum_contagiosum_virus R-HSA-933542 TRAF6 mediated NF-kB activation 15/1497 24/10654 5.7549508603288196e-8 2.4137269627786893e-7 9.959172328554047e-8 351/7186/4790/57506/4214/7706/5970/4792/3146/23586/64135/6288/7189/3551/4791 15 Molluscum_contagiosum_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 17/1497 30/10654 5.781037377668108e-8 2.416846594018667e-7 9.972044101376566e-8 7124/7186/6885/8737/7375/27005/7316/7128/7132/329/9099/6233/7311/8717/1540/3551/7314 17 Molluscum_contagiosum_virus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 24/1497 54/10654 5.8648872464677865e-8 2.444017322000724e-7 1.0084152043342819e-7 9318/5434/5440/5430/5436/5441/5438/5431/8450/5435/7316/9978/5433/10980/5437/1642/2033/5439/10987/6233/7311/7874/5432/7314 24 Molluscum_contagiosum_virus R-HSA-1295596 Spry regulation of FGF signaling 12/1497 16/10654 5.981940630528548e-8 2.461141287988888e-7 1.0154806483904769e-7 10253/5594/7316/6714/8569/867/6233/2885/7311/5781/7314/5595 12 Molluscum_contagiosum_virus R-HSA-193639 p75NTR signals via NF-kB 12/1497 16/10654 5.981940630528548e-8 2.461141287988888e-7 1.0154806483904769e-7 4790/4615/7316/5970/4792/4803/3654/7189/6233/7311/3551/7314 12 Molluscum_contagiosum_virus R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 12/1497 16/10654 5.981940630528548e-8 2.461141287988888e-7 1.0154806483904769e-7 5295/6464/5290/2205/2206/6850/4067/2534/2885/9846/5296/2207 12 Molluscum_contagiosum_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 12/1497 16/10654 5.981940630528548e-8 2.461141287988888e-7 1.0154806483904769e-7 8454/4790/5604/6500/7316/79155/23291/6233/7311/3551/6416/7314 12 Molluscum_contagiosum_virus R-HSA-5654741 Signaling by FGFR3 20/1497 40/10654 6.563873404701786e-8 2.69201896597896e-7 1.1107420684838466e-7 5295/10253/6464/5290/5335/5594/7316/6714/8569/2261/867/2247/6233/2885/7311/3845/3265/5781/7314/5595 20 Molluscum_contagiosum_virus R-HSA-5688426 Deubiquitination 76/1497 297/10654 6.889046313506414e-8 2.816468145837323e-7 1.1620904955209229e-7 23326/7186/6885/991/8737/83444/171023/7375/2625/57506/4303/57646/63967/409/6478/4086/1080/3091/5705/57695/11274/27005/7706/7316/993/79155/890/4792/983/8678/2099/4609/7415/9861/4194/23586/4089/8850/7128/3416/5701/329/6502/9099/4088/5698/5708/2033/408/64135/5728/5710/5702/7157/8900/9958/8975/4087/63891/7189/5704/6233/672/7048/7311/367/387/60/7040/1540/7874/154/5696/7314/4193/7528 76 Molluscum_contagiosum_virus R-HSA-9013694 Signaling by NOTCH4 31/1497 82/10654 7.281873041400045e-8 2.967706748947943e-7 1.2244923882923613e-7 8454/23462/207/55534/3280/6500/84441/5705/10046/7316/9978/9861/8850/5701/1387/4088/5698/5708/2033/55294/5710/5702/9794/5704/6233/7311/388585/3516/4851/5696/7314 31 Molluscum_contagiosum_virus R-HSA-69231 Cyclin D associated events in G1 21/1497 44/10654 8.659410958106608e-8 3.507061438033176e-7 1.4470331469467623e-7 8454/25/1019/1029/1027/6500/5925/7316/1869/5753/1026/6714/1871/5519/4067/3717/6502/595/6233/7311/7314 21 Molluscum_contagiosum_virus R-HSA-69236 G1 Phase 21/1497 44/10654 8.659410958106608e-8 3.507061438033176e-7 1.4470331469467623e-7 8454/25/1019/1029/1027/6500/5925/7316/1869/5753/1026/6714/1871/5519/4067/3717/6502/595/6233/7311/7314 21 Molluscum_contagiosum_virus R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 18/1497 34/10654 9.658930727139218e-8 3.875533814975984e-7 1.5990669087132878e-7 2963/5434/5440/5430/5436/6749/5441/5438/5431/5435/5433/2962/5437/5439/1025/11198/5432/25920 18 Molluscum_contagiosum_virus R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 18/1497 34/10654 9.658930727139218e-8 3.875533814975984e-7 1.5990669087132878e-7 2963/5434/5440/5430/5436/6749/5441/5438/5431/5435/5433/2962/5437/5439/1025/11198/5432/25920 18 Molluscum_contagiosum_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 18/1497 34/10654 9.658930727139218e-8 3.875533814975984e-7 1.5990669087132878e-7 29110/57506/9636/7706/7316/23586/7128/64135/83737/3661/9246/51191/6233/7311/5094/5300/1540/7314 18 Molluscum_contagiosum_virus R-HSA-69166 Removal of the Flap Intermediate 11/1497 14/10654 9.860540033221116e-8 3.9403982096544226e-7 1.625830320422715e-7 6118/2237/5557/5422/5425/5111/6119/23649/6117/5558/5424 11 Molluscum_contagiosum_virus R-HSA-983189 Kinesins 25/1497 59/10654 9.881399831309316e-8 3.9403982096544226e-7 1.625830320422715e-7 55582/84617/51807/23095/10382/29127/3832/7277/10381/7278/112714/23303/285643/10112/7846/113457/347733/10376/11004/10749/10383/24137/84790/9493/7280 25 Molluscum_contagiosum_virus R-HSA-73887 Death Receptor Signalling 44/1497 141/10654 1.194019877671443e-7 4.746778409393221e-7 1.958547296923129e-7 7124/8841/7186/4790/6885/10018/7531/8737/356/7375/835/7074/841/27005/4615/9500/7316/5970/4792/7128/7132/329/9099/843/836/4803/11108/3066/3065/3654/7189/6233/7409/7311/387/8772/5599/8717/1540/3551/8795/7314/5879/10672 44 Molluscum_contagiosum_virus R-HSA-72165 mRNA Splicing - Minor Pathway 23/1497 52/10654 1.234466382869122e-7 4.89256401283909e-7 2.018699251561288e-7 23451/2963/5434/5440/6632/5430/5436/23450/5441/5438/5431/5435/4686/5433/9343/2962/5437/5439/6634/5432/22916/10992/6628 23 Molluscum_contagiosum_virus R-HSA-1643713 Signaling by EGFR in Cancer 15/1497 25/10654 1.251763671996144e-7 4.930959631936178e-7 2.0345414985571628e-7 5295/6464/5290/5335/7316/1950/867/3320/6233/2885/7311/1956/3845/3265/7314 15 Molluscum_contagiosum_virus R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 15/1497 25/10654 1.251763671996144e-7 4.930959631936178e-7 2.0345414985571628e-7 23462/55534/3280/84441/10046/4854/6772/8850/1387/2033/9794/9787/388585/3516/4851 15 Molluscum_contagiosum_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 32/1497 88/10654 1.3020141674976126e-7 5.113364730536079e-7 2.1098028615272322e-7 5073/207/3184/3315/26986/5705/7316/9261/9861/1432/5701/5698/5708/1981/5710/5702/5704/6233/5580/7514/7311/8021/54464/5600/3312/8570/6418/5696/167227/7529/7314/1994 32 Molluscum_contagiosum_virus R-HSA-373760 L1CAM interactions 39/1497 119/10654 1.4682674822719796e-7 5.723279189091143e-7 2.361456975355995e-7 84617/6711/5604/51807/10382/5594/1460/7277/10381/3678/4478/2260/7278/112714/3688/3672/1457/285643/6714/5605/6710/7846/113457/347733/10376/214/6709/3685/6196/10383/24137/1956/60/84790/3312/288/7280/5879/5595 39 Molluscum_contagiosum_virus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 25/1497 60/10654 1.4698112562199288e-7 5.723279189091143e-7 2.361456975355995e-7 8454/1017/9134/1019/1027/6500/5705/7316/5753/890/1026/9861/5701/6502/5698/5708/595/5710/5702/8900/5704/6233/7311/5696/7314 25 Molluscum_contagiosum_virus R-HSA-2197563 NOTCH2 intracellular domain regulates transcription 10/1497 12/10654 1.4705647916414742e-7 5.723279189091143e-7 2.361456975355995e-7 2208/55534/3280/84441/10046/2033/9794/1385/388585/3516 10 Molluscum_contagiosum_virus R-HSA-69615 G1/S DNA Damage Checkpoints 27/1497 68/10654 1.553826410696313e-7 6.02921864749228e-7 2.4876893054955154e-7 1017/9134/1029/1027/11200/472/5705/7316/993/890/1026/9861/4194/5701/5698/5708/5710/1111/5702/7157/8900/5704/6233/7311/5696/7314/4193 27 Molluscum_contagiosum_virus R-HSA-9034015 Signaling by NTRK3 (TRKC) 12/1497 17/10654 1.7727410932390977e-7 6.858126736829464e-7 2.829701415131066e-7 5295/4908/6464/5290/3667/5335/6714/2885/3845/3265/4916/25920 12 Molluscum_contagiosum_virus R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 20/1497 42/10654 1.8456181948582566e-7 7.097688963015728e-7 2.928546128339823e-7 6118/5888/9156/5982/545/472/11073/641/6119/3364/10524/5985/84126/1111/5984/672/5983/6117/5884/5810 20 Molluscum_contagiosum_virus R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 20/1497 42/10654 1.8456181948582566e-7 7.097688963015728e-7 2.928546128339823e-7 2788/10694/54331/2770/10575/1460/7203/10576/908/1457/6950/2783/2782/2786/2771/10574/22948/10693/2773/2787 20 Molluscum_contagiosum_virus R-HSA-202424 Downstream TCR signaling 34/1497 98/10654 1.981730306176808e-7 7.598587209482671e-7 3.1352195438736173e-7 5295/8454/5290/4790/6885/6500/5705/919/7316/920/5970/4792/9861/5701/23291/915/917/5698/5708/5728/5710/916/5702/7189/5704/6233/7311/3932/5296/3127/3551/5696/997/7314 34 Molluscum_contagiosum_virus R-HSA-167172 Transcription of the HIV genome 28/1497 73/10654 2.175466095792598e-7 8.316826136127455e-7 3.431568938558112e-7 2963/5434/5440/2959/5430/6874/5436/6749/5441/5438/5431/5435/4686/5433/6872/2960/8731/2962/5437/5439/1025/6908/11198/2961/5432/22916/2957/25920 28 Molluscum_contagiosum_virus R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 13/1497 20/10654 2.3412816081348278e-7 8.924414600419814e-7 3.682263334156324e-7 23462/55534/3280/84441/10046/8850/1387/4088/2033/9794/388585/3516/4851 13 Molluscum_contagiosum_virus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 31/1497 86/10654 2.5624556323821524e-7 9.682048103694664e-7 3.994867151297018e-7 8454/1017/11065/991/9212/6500/5705/8881/7316/891/890/4085/983/6790/9861/5701/6502/5698/5708/5710/5702/8900/7324/9232/5704/6233/701/7311/5347/5696/7314 31 Molluscum_contagiosum_virus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 31/1497 86/10654 2.5624556323821524e-7 9.682048103694664e-7 3.994867151297018e-7 5295/26999/25/1072/5290/5335/51517/5747/5594/2268/919/3055/6850/6714/4067/917/3320/2534/695/2885/7525/3326/5580/7409/23191/60/5296/5581/10787/5879/5595 31 Molluscum_contagiosum_virus R-HSA-453276 Regulation of mitotic cell cycle 31/1497 86/10654 2.5624556323821524e-7 9.682048103694664e-7 3.994867151297018e-7 8454/1017/11065/991/9212/6500/5705/8881/7316/891/890/4085/983/6790/9861/5701/6502/5698/5708/5710/5702/8900/7324/9232/5704/6233/701/7311/5347/5696/7314 31 Molluscum_contagiosum_virus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 14/1497 23/10654 2.5952565686102886e-7 9.77747823522946e-7 4.0342421568360666e-7 6497/51592/7316/9611/9612/4089/7050/4088/142/3065/4087/6233/7311/7314 14 Molluscum_contagiosum_virus R-HSA-167287 HIV elongation arrest and recovery 18/1497 36/10654 3.004091900235682e-7 1.1252321106085098e-6 4.6427705668382313e-7 2963/5434/5440/5430/5436/6749/5441/5438/5431/5435/5433/2962/5437/5439/1025/11198/5432/25920 18 Molluscum_contagiosum_virus R-HSA-167290 Pausing and recovery of HIV elongation 18/1497 36/10654 3.004091900235682e-7 1.1252321106085098e-6 4.6427705668382313e-7 2963/5434/5440/5430/5436/6749/5441/5438/5431/5435/5433/2962/5437/5439/1025/11198/5432/25920 18 Molluscum_contagiosum_virus R-HSA-1236394 Signaling by ERBB4 24/1497 58/10654 3.0433915721079495e-7 1.1366672845682716e-6 4.689952733598782e-7 5295/6464/5290/2670/5241/348/6776/7316/1950/9611/4734/10413/6714/2099/83737/3925/6233/2885/7311/1956/3845/3265/7314/6387 24 Molluscum_contagiosum_virus R-HSA-5637810 Constitutive Signaling by EGFRvIII 11/1497 15/10654 3.2258083184198565e-7 1.1978932895908693e-6 4.942574651658233e-7 5295/6464/5290/5335/1950/867/3320/2885/1956/3845/3265 11 Molluscum_contagiosum_virus R-HSA-5637812 Signaling by EGFRvIII in Cancer 11/1497 15/10654 3.2258083184198565e-7 1.1978932895908693e-6 4.942574651658233e-7 5295/6464/5290/5335/1950/867/3320/2885/1956/3845/3265 11 Molluscum_contagiosum_virus R-HSA-167161 HIV Transcription Initiation 21/1497 47/10654 3.53643842591986e-7 1.2874225280876793e-6 5.311977292629476e-7 2963/5434/5440/2959/5430/6874/5436/5441/5438/5431/5435/5433/6872/2960/2962/5437/5439/6908/2961/5432/2957 21 Molluscum_contagiosum_virus R-HSA-167162 RNA Polymerase II HIV Promoter Escape 21/1497 47/10654 3.53643842591986e-7 1.2874225280876793e-6 5.311977292629476e-7 2963/5434/5440/2959/5430/6874/5436/5441/5438/5431/5435/5433/6872/2960/2962/5437/5439/6908/2961/5432/2957 21 Molluscum_contagiosum_virus R-HSA-437239 Recycling pathway of L1 21/1497 47/10654 3.53643842591986e-7 1.2874225280876793e-6 5.311977292629476e-7 84617/51807/10382/5594/7277/10381/4478/7278/112714/285643/6714/7846/113457/347733/10376/6196/10383/24137/60/84790/7280 21 Molluscum_contagiosum_virus R-HSA-73776 RNA Polymerase II Promoter Escape 21/1497 47/10654 3.53643842591986e-7 1.2874225280876793e-6 5.311977292629476e-7 2963/5434/5440/2959/5430/6874/5436/5441/5438/5431/5435/5433/6872/2960/2962/5437/5439/6908/2961/5432/2957 21 Molluscum_contagiosum_virus R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 21/1497 47/10654 3.53643842591986e-7 1.2874225280876793e-6 5.311977292629476e-7 2963/5434/5440/2959/5430/6874/5436/5441/5438/5431/5435/5433/6872/2960/2962/5437/5439/6908/2961/5432/2957 21 Molluscum_contagiosum_virus R-HSA-75953 RNA Polymerase II Transcription Initiation 21/1497 47/10654 3.53643842591986e-7 1.2874225280876793e-6 5.311977292629476e-7 2963/5434/5440/2959/5430/6874/5436/5441/5438/5431/5435/5433/6872/2960/2962/5437/5439/6908/2961/5432/2957 21 Molluscum_contagiosum_virus R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 21/1497 47/10654 3.53643842591986e-7 1.2874225280876793e-6 5.311977292629476e-7 2963/5434/5440/2959/5430/6874/5436/5441/5438/5431/5435/5433/6872/2960/2962/5437/5439/6908/2961/5432/2957 21 Molluscum_contagiosum_virus R-HSA-113418 Formation of the Early Elongation Complex 17/1497 33/10654 3.701028815432222e-7 1.3360817116434986e-6 5.512747803077464e-7 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/5439/5432/22916/25920 17 Molluscum_contagiosum_virus R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 17/1497 33/10654 3.701028815432222e-7 1.3360817116434986e-6 5.512747803077464e-7 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/5439/5432/22916/25920 17 Molluscum_contagiosum_virus R-HSA-5357905 Regulation of TNFR1 signaling 17/1497 33/10654 3.701028815432222e-7 1.3360817116434986e-6 5.512747803077464e-7 7124/7186/8737/7375/841/27005/7316/7128/7132/329/9099/6233/7311/8717/1540/3551/7314 17 Molluscum_contagiosum_virus R-HSA-5689880 Ub-specific processing proteases 59/1497 220/10654 3.743790119229199e-7 1.3477644429225116e-6 5.560951405170858e-7 23326/7186/6885/991/8737/7375/2625/4303/57646/63967/409/6478/4086/1080/3091/5705/57695/11274/27005/7316/993/890/4792/8678/4609/9861/4194/23586/4089/3416/5701/329/6502/9099/4088/5698/5708/408/64135/5728/5710/5702/7157/8900/9958/8975/4087/63891/7189/5704/6233/7311/367/1540/7874/154/5696/7314/4193 59 Molluscum_contagiosum_virus R-HSA-68875 Mitotic Prophase 43/1497 142/10654 4.2233996010661394e-7 1.516212155950614e-6 6.25597608205744e-7 4000/23165/5903/55706/7175/9631/5594/5925/348995/79023/9133/57122/23636/23310/7443/10762/10051/23511/891/53371/983/23279/4927/9688/79902/5519/9883/23225/8086/2010/64900/9972/55844/5347/54892/8021/129401/6418/55746/7112/10592/8480/5595 43 Molluscum_contagiosum_virus R-HSA-6804758 Regulation of TP53 Activity through Acetylation 16/1497 30/10654 4.413777671667881e-7 1.5801811774810977e-6 6.519915839509402e-7 9219/207/5931/84289/1108/5928/57459/54815/2033/3066/3065/7157/1107/5371/5300/53615 16 Molluscum_contagiosum_virus R-HSA-202403 TCR signaling 38/1497 119/10654 4.4770158775662145e-7 1.5984056686847974e-6 6.595111108608488e-7 5295/8454/5290/5335/4790/6885/6500/5705/5788/919/7316/920/5970/4792/9861/5701/23291/915/917/5698/5708/5728/1445/5710/916/5702/7189/5704/6233/7311/3932/5296/3127/3551/5062/5696/997/7314 38 Molluscum_contagiosum_virus R-HSA-5675482 Regulation of necroptotic cell death 12/1497 18/10654 4.6360284415593627e-7 1.6506299066650917e-6 6.810591232828677e-7 7186/8737/356/841/7316/329/6233/7311/8772/8717/8795/7314 12 Molluscum_contagiosum_virus R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 15/1497 27/10654 5.040616465893138e-7 1.7848740272670783e-6 7.364489976053249e-7 2963/5434/5440/5430/5436/5441/5438/5431/5435/5433/8731/2962/5437/5439/5432 15 Molluscum_contagiosum_virus R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 15/1497 27/10654 5.040616465893138e-7 1.7848740272670783e-6 7.364489976053249e-7 2963/5434/5440/5430/5436/5441/5438/5431/5435/5433/8731/2962/5437/5439/5432 15 Molluscum_contagiosum_virus R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 18/1497 37/10654 5.084789899370683e-7 1.7956097301319905e-6 7.408786085989695e-7 27161/8841/57690/27327/192670/348/9611/9612/2033/192669/23028/6256/23112/7376/4343/26523/8648/10062 18 Molluscum_contagiosum_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 13/1497 21/10654 5.353978137627542e-7 1.8855314310775257e-6 7.779808048955355e-7 4790/5567/5568/5970/5566/1387/4067/2534/2033/5971/3845/3265/5062 13 Molluscum_contagiosum_virus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 14/1497 24/10654 5.422922644218636e-7 1.9046362457743501e-6 7.858635581979938e-7 596/2309/5747/207/5594/1027/1950/595/2002/7514/1385/2353/1956/5595 14 Molluscum_contagiosum_virus R-HSA-5654743 Signaling by FGFR4 19/1497 41/10654 6.373471729442506e-7 2.2324376652317535e-6 9.21116255634934e-7 5295/10253/6464/5290/5335/5594/7316/6714/8569/867/2247/6233/2885/7311/3845/3265/5781/7314/5595 19 Molluscum_contagiosum_virus R-HSA-187687 Signalling to ERKs 17/1497 34/10654 6.436164558150508e-7 2.2483205572407167e-6 9.276696256321346e-7 6464/5604/5594/9261/6714/5605/1432/4914/4803/5603/2885/3845/5600/3265/6300/7529/5595 17 Molluscum_contagiosum_virus R-HSA-9012852 Signaling by NOTCH3 21/1497 49/10654 8.298878702446645e-7 2.8912222576265733e-6 1.192934459774447e-6 23462/55534/3280/84441/10046/7316/1950/4854/6772/8850/1387/2033/9794/6233/7311/1956/9787/388585/3516/4851/7314 21 Molluscum_contagiosum_virus R-HSA-5689896 Ovarian tumor domain proteases 18/1497 38/10654 8.397856103079565e-7 2.9178609945284497e-6 1.2039257514786e-6 8737/57506/7706/7316/79155/983/2099/7415/23586/7128/64135/5728/7157/7189/6233/7311/387/7314 18 Molluscum_contagiosum_virus R-HSA-2586552 Signaling by Leptin 9/1497 11/10654 8.791246282148863e-7 3.038254715110647e-6 1.2536008733562452e-6 3667/3953/9021/3952/6776/6774/3717/6777/5781 9 Molluscum_contagiosum_virus R-HSA-9020956 Interleukin-27 signaling 9/1497 11/10654 8.791246282148863e-7 3.038254715110647e-6 1.2536008733562452e-6 10148/6774/6772/3717/9466/3716/246778/7297/3572 9 Molluscum_contagiosum_virus R-HSA-9614657 FOXO-mediated transcription of cell death genes 11/1497 16/10654 9.00655968022731e-7 3.0963371996926572e-6 1.2775660310622726e-6 2308/2309/65018/10018/356/4303/1649/4800/1387/2033/604 11 Molluscum_contagiosum_virus R-HSA-5617472 Activation of anterior HOX genes in hindbrain development during early embryogenesis 38/1497 122/10654 9.030983499103584e-7 3.0963371996926572e-6 1.2775660310622726e-6 9070/3725/5434/5440/8841/11091/2146/5430/8085/5436/5929/5931/5441/3213/5438/5431/7403/5435/5433/9611/9935/5928/22976/1387/5437/2033/23512/5439/6256/58508/23054/9063/8726/57472/8202/5432/1959/7528 38 Molluscum_contagiosum_virus R-HSA-5619507 Activation of HOX genes during differentiation 38/1497 122/10654 9.030983499103584e-7 3.0963371996926572e-6 1.2775660310622726e-6 9070/3725/5434/5440/8841/11091/2146/5430/8085/5436/5929/5931/5441/3213/5438/5431/7403/5435/5433/9611/9935/5928/22976/1387/5437/2033/23512/5439/6256/58508/23054/9063/8726/57472/8202/5432/1959/7528 38 Molluscum_contagiosum_virus R-HSA-5610787 Hedgehog 'off' state 36/1497 113/10654 9.519933251908046e-7 3.2553650381194797e-6 1.3431818058517673e-6 8454/84617/5567/1452/10382/5568/6500/7277/10381/5705/7278/7316/9978/2778/9861/5566/2932/5701/7846/5576/113457/5698/347733/5708/10376/5710/5702/83737/5704/6233/7311/10383/84790/5696/7280/7314 36 Molluscum_contagiosum_virus R-HSA-3858494 Beta-catenin independent WNT signaling 43/1497 146/10654 9.77984648309593e-7 3.3354423794979804e-6 1.3762221643802585e-6 2788/57154/27161/815/54331/6885/1499/4772/5532/57690/27327/409/5705/192670/5530/7316/6934/9861/5701/5698/5708/5880/2783/5710/2782/5702/192669/2786/23112/5704/6233/1855/7474/1857/7311/387/4343/3845/26523/5696/7314/5879/2787 43 Molluscum_contagiosum_virus R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 14/1497 25/10654 1.0731670427047295e-6 3.640901799333323e-6 1.5022564279250557e-6 1017/994/2305/9133/891/993/890/983/5519/995/8900/7514/5347/7465 14 Molluscum_contagiosum_virus R-HSA-9006335 Signaling by Erythropoietin 14/1497 25/10654 1.0731670427047295e-6 3.640901799333323e-6 1.5022564279250557e-6 5295/6464/5290/5335/6776/4067/3717/2057/2885/2056/7409/3845/6777/3265 14 Molluscum_contagiosum_virus R-HSA-8953750 Transcriptional Regulation by E2F6 17/1497 35/10654 1.08825486521406e-6 3.6824498833353047e-6 1.5193993995568022e-6 5888/2146/8317/6045/80012/5931/4149/1869/1911/5928/10138/23512/1111/672/8726/6015/6241 17 Molluscum_contagiosum_virus R-HSA-3247509 Chromatin modifying enzymes 68/1497 274/10654 1.1286898024099853e-6 3.79943372447621e-6 1.567667586122413e-6 84678/54014/6595/9070/10196/1019/8841/23326/55250/11091/4790/6597/23186/2146/5978/9112/9219/8085/6871/5929/5931/8520/6598/6599/7403/9611/84289/5970/11143/9612/1108/2122/84444/8850/5928/10524/1387/55578/57459/3717/6604/8289/54815/2033/23512/6605/6602/595/23210/3066/3065/1107/23028/23135/10498/57504/80854/58508/1386/51317/60/8726/3276/6601/6187/53615/8648/4791 68 Molluscum_contagiosum_virus R-HSA-4839726 Chromatin organization 68/1497 274/10654 1.1286898024099853e-6 3.79943372447621e-6 1.567667586122413e-6 84678/54014/6595/9070/10196/1019/8841/23326/55250/11091/4790/6597/23186/2146/5978/9112/9219/8085/6871/5929/5931/8520/6598/6599/7403/9611/84289/5970/11143/9612/1108/2122/84444/8850/5928/10524/1387/55578/57459/3717/6604/8289/54815/2033/23512/6605/6602/595/23210/3066/3065/1107/23028/23135/10498/57504/80854/58508/1386/51317/60/8726/3276/6601/6187/53615/8648/4791 68 Molluscum_contagiosum_virus R-HSA-389357 CD28 dependent PI3K/Akt signaling 13/1497 22/10654 1.1402510186854912e-6 3.8124116802813523e-6 1.573022363209005e-6 5295/5290/207/941/64223/8503/2534/942/79109/2475/3932/5296/253260 13 Molluscum_contagiosum_virus R-HSA-9613829 Chaperone Mediated Autophagy 13/1497 22/10654 1.1402510186854912e-6 3.8124116802813523e-6 1.573022363209005e-6 2670/1915/1080/10013/7316/3320/6233/3326/7311/7431/3312/11315/7314 13 Molluscum_contagiosum_virus R-HSA-167169 HIV Transcription Elongation 20/1497 46/10654 1.147253514899481e-6 3.8124116802813523e-6 1.573022363209005e-6 2963/5434/5440/5430/5436/6749/5441/5438/5431/5435/4686/5433/2962/5437/5439/1025/11198/5432/22916/25920 20 Molluscum_contagiosum_virus R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 20/1497 46/10654 1.147253514899481e-6 3.8124116802813523e-6 1.573022363209005e-6 2963/5434/5440/5430/5436/6749/5441/5438/5431/5435/4686/5433/2962/5437/5439/1025/11198/5432/22916/25920 20 Molluscum_contagiosum_virus R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 20/1497 46/10654 1.147253514899481e-6 3.8124116802813523e-6 1.573022363209005e-6 2963/5434/5440/5430/5436/6749/5441/5438/5431/5435/4686/5433/2962/5437/5439/1025/11198/5432/22916/25920 20 Molluscum_contagiosum_virus R-HSA-69563 p53-Dependent G1 DNA Damage Response 25/1497 66/10654 1.268471173007543e-6 4.193721020963714e-6 1.730352727947991e-6 1017/9134/1029/1027/11200/472/5705/7316/890/1026/9861/4194/5701/5698/5708/5710/5702/7157/8900/5704/6233/7311/5696/7314/4193 25 Molluscum_contagiosum_virus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 25/1497 66/10654 1.268471173007543e-6 4.193721020963714e-6 1.730352727947991e-6 1017/9134/1029/1027/11200/472/5705/7316/890/1026/9861/4194/5701/5698/5708/5710/5702/7157/8900/5704/6233/7311/5696/7314/4193 25 Molluscum_contagiosum_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 29/1497 83/10654 1.3086138956560503e-6 4.315429029949723e-6 1.7805701325653507e-6 8454/4773/4790/6885/5966/4772/5532/4775/6500/5705/5530/7316/5970/4792/9861/5701/23291/5698/5708/5710/5702/5704/6233/7311/3845/3265/3551/5696/7314 29 Molluscum_contagiosum_virus R-HSA-75893 TNF signaling 19/1497 43/10654 1.5747912781077319e-6 5.180024102608174e-6 2.1373068909396946e-6 7124/7186/6885/8737/7375/841/27005/7316/7128/7132/329/9099/6233/7311/8772/8717/1540/3551/7314 19 Molluscum_contagiosum_virus R-HSA-72163 mRNA Splicing - Major Pathway 50/1497 183/10654 1.5912701938950837e-6 5.220977648830452e-6 2.154204552961233e-6 23451/2963/5434/5440/220988/6632/10946/11051/5430/5436/6428/3184/3178/23450/5441/5438/5431/5093/5435/4686/5433/11338/1655/9343/3190/2962/988/5437/4670/10189/6631/3181/5439/1660/3187/1665/6634/5094/51593/9775/3192/3312/10291/5432/22916/56259/5725/10992/6628/1994 50 Molluscum_contagiosum_virus R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 10/1497 14/10654 1.7012271832938884e-6 5.532979504245552e-6 2.282938261985657e-6 6118/4436/9156/2956/3978/5425/5111/6119/6117/5424 10 Molluscum_contagiosum_virus R-HSA-8941856 RUNX3 regulates NOTCH signaling 10/1497 14/10654 1.7012271832938884e-6 5.532979504245552e-6 2.282938261985657e-6 55534/3280/84441/10046/8850/1387/2033/9794/3516/4851 10 Molluscum_contagiosum_virus R-HSA-918233 TRAF3-dependent IRF activation pathway 10/1497 14/10654 1.7012271832938884e-6 5.532979504245552e-6 2.282938261985657e-6 3665/29110/57506/7706/23586/1387/2033/64135/3661/3456 10 Molluscum_contagiosum_virus R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK 15/1497 29/10654 1.7034404492237465e-6 5.532979504245552e-6 2.282938261985657e-6 389541/7249/58528/153129/64223/10325/8649/6009/10542/2475/55004/10670/64121/57521/28956 15 Molluscum_contagiosum_virus R-HSA-674695 RNA Polymerase II Pre-transcription Events 29/1497 84/10654 1.7336647535586252e-6 5.566103566150764e-6 2.2966054350264686e-6 2963/5434/5440/2959/5430/6874/5436/9646/6749/5441/5438/5431/5435/4686/5433/6872/2960/2962/5437/5439/1025/23168/6908/11198/2961/5432/22916/2957/25920 29 Molluscum_contagiosum_virus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 20/1497 47/10654 1.7351125314235406e-6 5.566103566150764e-6 2.2966054350264686e-6 818/815/5604/8844/817/5594/409/6714/5605/3717/2335/408/1445/816/60/3845/3265/5245/7529/5595 20 Molluscum_contagiosum_virus R-HSA-6802949 Signaling by RAS mutants 20/1497 47/10654 1.7351125314235406e-6 5.566103566150764e-6 2.2966054350264686e-6 818/815/5604/8844/817/5594/409/6714/5605/3717/2335/408/1445/816/60/3845/3265/5245/7529/5595 20 Molluscum_contagiosum_virus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 20/1497 47/10654 1.7351125314235406e-6 5.566103566150764e-6 2.2966054350264686e-6 818/815/5604/8844/817/5594/409/6714/5605/3717/2335/408/1445/816/60/3845/3265/5245/7529/5595 20 Molluscum_contagiosum_virus R-HSA-9649948 Signaling downstream of RAS mutants 20/1497 47/10654 1.7351125314235406e-6 5.566103566150764e-6 2.2966054350264686e-6 818/815/5604/8844/817/5594/409/6714/5605/3717/2335/408/1445/816/60/3845/3265/5245/7529/5595 20 Molluscum_contagiosum_virus R-HSA-442755 Activation of NMDA receptors and postsynaptic events 31/1497 93/10654 1.8202678263172555e-6 5.824857044215218e-6 2.4033685660017307e-6 818/84617/815/3838/5567/51807/817/10382/5594/5568/7277/10381/7278/112714/6714/5566/7846/5576/113457/347733/10376/816/1385/6196/10383/84790/3845/3265/7280/5879/5595 31 Molluscum_contagiosum_virus R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 21/1497 51/10654 1.8351599313005875e-6 5.858047465432417e-6 2.4170631192654875e-6 84617/5321/51807/10382/7277/10381/23299/7278/112714/1780/1639/636/7846/113457/347733/10376/10540/10383/84790/5049/7280 21 Molluscum_contagiosum_virus R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 23/1497 59/10654 1.8746591998569646e-6 5.969430769077705e-6 2.4630204927643555e-6 5000/23594/5705/7316/84515/9861/51053/4998/5701/5698/5708/990/5710/81620/5702/5704/6233/23595/7311/5001/5696/4999/7314 23 Molluscum_contagiosum_virus R-HSA-912694 Regulation of IFNA signaling 14/1497 26/10654 2.024844199966132e-6 6.431858046951243e-6 2.653820571679038e-6 5777/5770/3455/9021/11274/6772/8651/3454/3439/3716/3456/6773/7297/5781 14 Molluscum_contagiosum_virus R-HSA-4655427 SUMOylation of DNA methylation proteins 11/1497 17/10654 2.2268560423038957e-6 7.056247997129215e-6 2.9114473542410997e-6 1912/8535/1786/6045/80012/1911/7341/84733/57332/7329/6015 11 Molluscum_contagiosum_virus R-HSA-167044 Signalling to RAS 12/1497 20/10654 2.391502901192322e-6 7.504570847325058e-6 3.0964278674798e-6 6464/9261/6714/1432/4914/4803/5603/2885/3845/5600/3265/6300 12 Molluscum_contagiosum_virus R-HSA-3232118 SUMOylation of transcription factors 12/1497 20/10654 2.391502901192322e-6 7.504570847325058e-6 3.0964278674798e-6 7020/1029/9112/51588/3090/7341/10401/7157/7329/9063/4193/8554 12 Molluscum_contagiosum_virus R-HSA-5213460 RIPK1-mediated regulated necrosis 12/1497 20/10654 2.391502901192322e-6 7.504570847325058e-6 3.0964278674798e-6 7186/8737/356/841/7316/329/6233/7311/8772/8717/8795/7314 12 Molluscum_contagiosum_virus R-HSA-5218859 Regulated Necrosis 12/1497 20/10654 2.391502901192322e-6 7.504570847325058e-6 3.0964278674798e-6 7186/8737/356/841/7316/329/6233/7311/8772/8717/8795/7314 12 Molluscum_contagiosum_virus R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 20/1497 48/10654 2.5844713866965027e-6 8.090519123571662e-6 3.3381934005640056e-6 2963/5434/5440/5430/5436/6749/5441/5438/5431/5435/4686/5433/2962/5437/5439/1025/11198/5432/22916/25920 20 Molluscum_contagiosum_virus R-HSA-2029481 FCGR activation 9/1497 12/10654 3.075329075367108e-6 9.557857270205688e-6 3.9436253194156025e-6 2268/919/3055/6850/6714/4067/917/2534/7525 9 Molluscum_contagiosum_virus R-HSA-210990 PECAM1 interactions 9/1497 12/10654 3.075329075367108e-6 9.557857270205688e-6 3.9436253194156025e-6 5777/5335/6714/4067/2534/7525/3685/3932/5781 9 Molluscum_contagiosum_virus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 9/1497 12/10654 3.075329075367108e-6 9.557857270205688e-6 3.9436253194156025e-6 8737/57506/841/7706/23586/843/64135/8772/3551 9 Molluscum_contagiosum_virus R-HSA-9609736 Assembly and cell surface presentation of NMDA receptors 18/1497 41/10654 3.3213818664454815e-6 1.0297872963907523e-5 4.248959929877372e-6 818/84617/815/51807/817/10382/7277/10381/7278/112714/7846/113457/347733/10376/816/10383/84790/7280 18 Molluscum_contagiosum_virus R-HSA-1538133 G0 and Early G1 14/1497 27/10654 3.6626100266796216e-6 1.1328741275839592e-5 4.674301955918222e-6 1017/9134/7153/4149/1869/993/890/983/5111/4609/5928/990/3065/8900 14 Molluscum_contagiosum_virus R-HSA-9612973 Autophagy 36/1497 119/10654 3.7144918291502387e-6 1.146186050137788e-5 4.729227692251432e-6 2670/65018/1915/389541/7249/58528/1080/1460/10533/10013/153129/7316/1457/8678/6714/64223/10325/8649/3320/6009/55054/10542/6233/3326/2475/55004/7311/10670/7251/7431/3312/11315/64121/57521/7314/28956 36 Molluscum_contagiosum_virus R-HSA-177929 Signaling by EGFR 20/1497 49/10654 3.794528984249483e-6 1.1681020341062541e-5 4.8196542667801916e-6 5295/10253/6464/5290/5335/58513/7316/1950/6714/867/1445/6233/2885/7311/1956/3845/3265/5781/10252/7314 20 Molluscum_contagiosum_virus R-HSA-6807505 RNA polymerase II transcribes snRNA genes 26/1497 74/10654 4.0666266836566975e-6 1.2488976734642371e-5 5.153021589667255e-6 2963/5434/5440/55197/2959/5430/5436/5451/5441/5438/5431/5435/4686/5433/2960/6667/2962/5437/5439/1025/6908/51593/2961/5432/22916/2957 26 Molluscum_contagiosum_virus R-HSA-5358508 Mismatch Repair 10/1497 15/10654 4.458519886197676e-6 1.3627928708755163e-5 5.622959538700149e-6 6118/4436/9156/2956/3978/5425/5111/6119/6117/5424 10 Molluscum_contagiosum_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 10/1497 15/10654 4.458519886197676e-6 1.3627928708755163e-5 5.622959538700149e-6 54106/3665/4615/7316/3654/7189/6233/51311/7311/7314 10 Molluscum_contagiosum_virus R-HSA-445144 Signal transduction by L1 12/1497 21/10654 4.866309684431729e-6 1.4804547772355682e-5 6.108439139341039e-6 5604/5594/1460/3678/2260/3688/1457/5605/3685/1956/5879/5595 12 Molluscum_contagiosum_virus R-HSA-9008059 Interleukin-37 signaling 12/1497 21/10654 4.866309684431729e-6 1.4804547772355682e-5 6.108439139341039e-6 834/5777/5783/27178/29110/6774/59307/8809/4088/5771/5784/5781 12 Molluscum_contagiosum_virus R-HSA-1368082 RORA activates gene expression 11/1497 18/10654 4.997682496536427e-6 1.516861010658363e-5 6.2586532928398995e-6 6095/1374/5465/5469/1387/6604/2033/6256/10498/23054/8648 11 Molluscum_contagiosum_virus R-HSA-4086398 Ca2+ pathway 23/1497 62/10654 5.079266510927019e-6 1.5380208874208916e-5 6.345960126785356e-6 2788/27161/815/54331/6885/1499/4772/5532/57690/27327/192670/5530/6934/2783/2782/192669/2786/23112/7474/4343/3845/26523/2787 23 Molluscum_contagiosum_virus R-HSA-5654736 Signaling by FGFR1 20/1497 50/10654 5.495691586081075e-6 1.660236898732185e-5 6.850230218940464e-6 5295/10253/6464/5290/5335/5594/2260/7316/6714/8569/867/2247/6233/2885/7311/3845/3265/5781/7314/5595 20 Molluscum_contagiosum_virus R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 28/1497 84/10654 5.684120412471991e-6 1.7131674545496976e-5 7.068624650026368e-6 7124/1052/1019/8841/4790/5468/1051/3952/688/5465/9611/5469/1050/5970/9612/1387/6604/2033/6256/10498/4023/23054/7040/27332/8202/8648/1959/10891 28 Molluscum_contagiosum_virus R-HSA-6802957 Oncogenic MAPK signaling 25/1497 71/10654 5.936428450724703e-6 1.7850606199858967e-5 7.365259868037976e-6 4000/818/815/8805/5604/10018/8844/817/5594/409/10533/6714/5605/3717/2335/408/1445/816/60/3845/3265/4763/5245/7529/5595 25 Molluscum_contagiosum_virus R-HSA-194315 Signaling by Rho GTPases 98/1497 455/10654 5.99132045441806e-6 1.797396136325418e-5 7.416156897768944e-6 26999/5905/11130/84617/25/5903/1072/10403/51517/55143/1499/7531/5747/1058/55789/991/79019/51807/2316/10928/3633/10382/9212/5594/613/29127/7074/1027/3619/388/1080/7277/348995/79023/10381/57122/58480/7278/6232/332/112714/1780/6242/5528/3688/4085/5585/6714/23279/79902/5519/1432/2017/699/7846/999/113457/347733/5880/85360/995/10376/9322/58504/397/23221/23028/695/11004/90627/1855/2885/5580/701/7409/1857/9055/23191/7514/23380/57120/367/10383/5347/387/60/5296/5300/84790/5600/5062/55746/7280/7529/10787/5879/5595/10672 98 Molluscum_contagiosum_virus R-HSA-72172 mRNA Splicing 50/1497 191/10654 6.039951866255776e-6 1.8078008357199737e-5 7.45908726889008e-6 23451/2963/5434/5440/220988/6632/10946/11051/5430/5436/6428/3184/3178/23450/5441/5438/5431/5093/5435/4686/5433/11338/1655/9343/3190/2962/988/5437/4670/10189/6631/3181/5439/1660/3187/1665/6634/5094/51593/9775/3192/3312/10291/5432/22916/56259/5725/10992/6628/1994 50 Molluscum_contagiosum_virus R-HSA-114604 GPVI-mediated activation cascade 16/1497 35/10654 6.142601672933308e-6 1.8342884258344625e-5 7.568376545840699e-6 5295/5777/5290/388/6850/8503/4067/5880/2534/7409/3932/387/5296/5781/2207/5879 16 Molluscum_contagiosum_virus R-HSA-69205 G1/S-Specific Transcription 14/1497 28/10654 6.380382341307078e-6 1.8981659134523533e-5 7.83193862925435e-6 8318/5422/1869/983/5111/4998/5928/990/81620/3065/8900/7298/1719/6241 14 Molluscum_contagiosum_virus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 27/1497 80/10654 6.385805079206991e-6 1.8981659134523533e-5 7.83193862925435e-6 8454/1017/11065/991/6500/5705/8881/7316/891/890/4085/983/9861/5701/5698/5708/5710/5702/8900/7324/5704/6233/701/7311/5347/5696/7314 27 Molluscum_contagiosum_virus R-HSA-73762 RNA Polymerase I Transcription Initiation 19/1497 47/10654 7.830612787093437e-6 2.3170032356331265e-5 9.560084825386846e-6 5434/5440/9112/9219/5931/5441/5435/1108/8850/5928/5437/57459/54815/3066/3065/1107/57504/6908/53615 19 Molluscum_contagiosum_virus R-HSA-9024446 NR1H2 and NR1H3-mediated signaling 19/1497 47/10654 7.830612787093437e-6 2.3170032356331265e-5 9.560084825386846e-6 27161/8841/8204/57690/27327/192670/348/9611/9612/2033/192669/23028/6256/23112/7376/4343/26523/8648/10062 19 Molluscum_contagiosum_virus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 13/1497 25/10654 7.889458487806759e-6 2.329097539908328e-5 9.609986600661391e-6 5594/5528/4205/9261/5519/5598/1432/4208/2002/1385/6196/5600/5595 13 Molluscum_contagiosum_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 15/1497 32/10654 8.196948101086952e-6 2.4034490359748165e-5 9.916765028226178e-6 57154/10273/7316/4089/867/4088/9958/9040/4087/6233/7514/7048/7311/7040/7314 15 Molluscum_contagiosum_virus R-HSA-381042 PERK regulates gene expression 15/1497 32/10654 8.196948101086952e-6 2.4034490359748165e-5 9.916765028226178e-6 1965/5073/1051/1649/3576/468/4800/1054/8894/9451/6347/467/8570/167227/1968 15 Molluscum_contagiosum_virus R-HSA-5673000 RAF activation 15/1497 32/10654 8.196948101086952e-6 2.4034490359748165e-5 9.916765028226178e-6 818/815/5604/8844/817/5528/6714/5605/5519/3717/816/3845/3265/5245/7529 15 Molluscum_contagiosum_virus R-HSA-209543 p75NTR recruits signalling complexes 9/1497 13/10654 8.742700483720227e-6 2.5576839338377908e-5 1.055314683552305e-5 4615/7316/4803/3654/7189/6233/7311/3551/7314 9 Molluscum_contagiosum_virus R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 35/1497 119/10654 1.0098477650579988e-5 2.9476637466557802e-5 1.2162225335454324e-5 6095/6822/8841/1374/5468/51/5465/406/335/9611/5469/4800/9612/6667/336/1387/6604/2033/2101/4199/6256/7376/2168/10498/183/2274/23054/25942/196/405/8202/133522/8648/10891/10062 35 Molluscum_contagiosum_virus R-HSA-6804760 Regulation of TP53 Activity through Methylation 11/1497 19/10654 1.0361013600947069e-5 3.0119077932371677e-5 1.2427299861634841e-5 11200/472/7316/4194/2033/7157/6233/7311/26013/7314/4193 11 Molluscum_contagiosum_virus R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 10/1497 16/10654 1.0388293083155973e-5 3.0119077932371677e-5 1.2427299861634841e-5 55534/3280/84441/10046/8850/1387/2033/9794/3516/4851 10 Molluscum_contagiosum_virus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 10/1497 16/10654 1.0388293083155973e-5 3.0119077932371677e-5 1.2427299861634841e-5 57154/50848/7316/6233/7048/7311/387/7040/57530/7314 10 Molluscum_contagiosum_virus R-HSA-111885 Opioid Signalling 29/1497 91/10654 1.055398532920714e-5 3.051001014188267e-5 1.2588600675825534e-5 2788/818/815/3838/5321/54331/5567/2770/817/5532/5594/5568/5530/5528/5443/5566/5519/4988/5576/2783/2782/816/2786/2771/5580/1385/1020/2773/2787 29 Molluscum_contagiosum_virus R-HSA-5674135 MAP2K and MAPK activation 17/1497 40/10654 1.0593753521487038e-5 3.051001014188267e-5 1.2588600675825534e-5 5604/8844/84292/5594/409/6714/5605/8649/2335/408/1445/60/3845/3265/7529/28956/5595 17 Molluscum_contagiosum_virus R-HSA-5675221 Negative regulation of MAPK pathway 17/1497 40/10654 1.0593753521487038e-5 3.051001014188267e-5 1.2588600675825534e-5 1844/5604/8844/5594/5528/7316/5605/5519/1847/6233/7311/1843/3845/3265/7529/7314/5595 17 Molluscum_contagiosum_virus R-HSA-5654732 Negative regulation of FGFR3 signaling 14/1497 29/10654 1.0745528107251489e-5 3.0705286407707174e-5 1.2669172754317126e-5 10253/5594/7316/6714/8569/2261/867/2247/6233/2885/7311/5781/7314/5595 14 Molluscum_contagiosum_virus R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 14/1497 29/10654 1.0745528107251489e-5 3.0705286407707174e-5 1.2669172754317126e-5 2308/2309/4303/5443/4089/4088/2908/3630/3066/3065/6648/4087/25942/10891 14 Molluscum_contagiosum_virus R-HSA-9619483 Activation of AMPK downstream of NMDARs 14/1497 29/10654 1.0745528107251489e-5 3.0705286407707174e-5 1.2669172754317126e-5 84617/51807/10382/7277/10381/7278/112714/7846/113457/347733/10376/10383/84790/7280 14 Molluscum_contagiosum_virus R-HSA-2871837 FCERI mediated NF-kB activation 27/1497 82/10654 1.0756327182946804e-5 3.0705286407707174e-5 1.2669172754317126e-5 8454/2205/4790/6885/6500/5705/2206/7316/5970/4792/9861/5701/4067/23291/5698/5708/5710/5702/7189/5704/6233/7311/3551/5696/997/2207/7314 27 Molluscum_contagiosum_virus R-HSA-75153 Apoptotic execution phase 20/1497 52/10654 1.1096872540456103e-5 3.160779519215629e-5 1.3041552922039793e-5 4000/3837/1499/5747/63967/841/100506658/660/3146/329/999/836/3836/5580/6709/839/840/7431/5062/6304 20 Molluscum_contagiosum_virus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 18/1497 44/10654 1.1124172248902145e-5 3.161606849687978e-5 1.30449665338003e-5 6497/51592/3726/7316/9611/9612/6667/4609/4089/7050/4088/142/3065/4087/6233/1025/7311/7314 18 Molluscum_contagiosum_virus R-HSA-2871809 FCERI mediated Ca+2 mobilization 15/1497 33/10654 1.308473231096937e-5 3.702579274021027e-5 1.527704898637656e-5 6464/4773/2205/5335/4772/5532/4775/2206/5530/6850/4067/695/2885/7409/2207 15 Molluscum_contagiosum_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 15/1497 33/10654 1.308473231096937e-5 3.702579274021027e-5 1.527704898637656e-5 351/4790/6885/7316/5970/4792/3146/6288/3654/7189/6233/7311/3551/4791/7314 15 Molluscum_contagiosum_virus R-HSA-112382 Formation of RNA Pol II elongation complex 22/1497 61/10654 1.3733357446052694e-5 3.869224184800933e-5 1.5964635200445694e-5 2963/5434/5440/5430/5436/9646/6749/5441/5438/5431/5435/4686/5433/2962/5437/5439/1025/23168/11198/5432/22916/25920 22 Molluscum_contagiosum_virus R-HSA-75955 RNA Polymerase II Transcription Elongation 22/1497 61/10654 1.3733357446052694e-5 3.869224184800933e-5 1.5964635200445694e-5 2963/5434/5440/5430/5436/9646/6749/5441/5438/5431/5435/4686/5433/2962/5437/5439/1025/23168/11198/5432/22916/25920 22 Molluscum_contagiosum_virus R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 8/1497 11/10654 1.6577045334085292e-5 4.650184145665484e-5 1.9186919639360512e-5 7422/3091/1387/2033/2056/2034/405/768 8 Molluscum_contagiosum_virus R-HSA-174414 Processive synthesis on the C-strand of the telomere 8/1497 11/10654 1.6577045334085292e-5 4.650184145665484e-5 1.9186919639360512e-5 6118/2237/3978/5425/5111/6119/6117/5424 8 Molluscum_contagiosum_virus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 12/1497 23/10654 1.7031092186167117e-5 4.7672344434714007e-5 1.966987570893008e-5 5601/6885/7316/5602/3654/7189/5609/6233/7311/5599/6416/7314 12 Molluscum_contagiosum_virus R-HSA-2424491 DAP12 signaling 14/1497 30/10654 1.7553049961225962e-5 4.9027484374458725e-5 2.0229014020650613e-5 5295/6464/5290/5335/567/6850/2534/695/2885/3932/5296/3845/3265/5879 14 Molluscum_contagiosum_virus R-HSA-1234174 Cellular response to hypoxia 25/1497 75/10654 1.7799211687418815e-5 4.9608125477193086e-5 2.0468589784286948e-5 112399/7422/3091/5705/7316/9978/8994/9861/5701/1387/5698/5708/2033/5710/5702/5704/6233/2056/7311/2034/55662/405/5696/768/7314 25 Molluscum_contagiosum_virus R-HSA-1989781 PPARA activates gene expression 34/1497 117/10654 1.7846742867452118e-5 4.9633859991884e-5 2.0479207988854026e-5 6095/6822/8841/1374/5468/51/5465/406/335/9611/5469/4800/9612/6667/336/1387/6604/2033/2101/4199/6256/7376/2168/10498/183/2274/23054/196/405/8202/133522/8648/10891/10062 34 Molluscum_contagiosum_virus R-HSA-162594 Early Phase of HIV Life Cycle 9/1497 14/10654 2.141735242448774e-5 5.9057210089651304e-5 2.4367334897289525e-5 2237/7852/3159/3978/3981/920/3836/2547/1234 9 Molluscum_contagiosum_virus R-HSA-198323 AKT phosphorylates targets in the cytosol 9/1497 14/10654 2.141735242448774e-5 5.9057210089651304e-5 2.4367334897289525e-5 842/207/84335/1027/7249/1026/2932/2931/4193 9 Molluscum_contagiosum_virus R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 9/1497 14/10654 2.141735242448774e-5 5.9057210089651304e-5 2.4367334897289525e-5 6118/4436/9156/3978/5425/5111/6119/6117/5424 9 Molluscum_contagiosum_virus R-HSA-9027284 Erythropoietin activates RAS 9/1497 14/10654 2.141735242448774e-5 5.9057210089651304e-5 2.4367334897289525e-5 6464/4067/3717/2057/2885/2056/7409/3845/3265 9 Molluscum_contagiosum_virus R-HSA-6788467 IL-6-type cytokine receptor ligand interactions 10/1497 17/10654 2.2047488855801655e-5 6.065382149422349e-5 2.5026105684751082e-5 3589/3976/3717/3716/1270/5008/3977/7297/1489/3572 10 Molluscum_contagiosum_virus R-HSA-111465 Apoptotic cleavage of cellular proteins 16/1497 38/10654 2.218357360205396e-5 6.065382149422349e-5 2.5026105684751082e-5 4000/1499/5747/63967/841/100506658/660/329/999/836/5580/6709/839/840/7431/6304 16 Molluscum_contagiosum_virus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 16/1497 38/10654 2.218357360205396e-5 6.065382149422349e-5 2.5026105684751082e-5 7020/3815/7422/4869/2064/348/1026/2099/4609/3329/7341/1387/2033/7329/1956/7528 16 Molluscum_contagiosum_virus R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 16/1497 38/10654 2.218357360205396e-5 6.065382149422349e-5 2.5026105684751082e-5 1072/27250/6775/1265/4478/3313/6175/6647/6950/3458/3181/6648/2939/302/5062/3586 16 Molluscum_contagiosum_virus R-HSA-6802952 Signaling by BRAF and RAF fusions 23/1497 67/10654 2.232139047795293e-5 6.0902151704056835e-5 2.512856811700851e-5 4000/818/815/8805/5604/10018/8844/817/5594/409/10533/6714/5605/3717/2335/408/1445/816/60/3845/3265/7529/5595 23 Molluscum_contagiosum_virus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 25/1497 76/10654 2.3030557136065802e-5 6.270504632004471e-5 2.5872452510219876e-5 11065/991/5705/8881/7316/891/890/4085/983/9861/5701/5698/5708/5710/5702/8900/7324/9232/5704/6233/701/7311/5347/5696/7314 25 Molluscum_contagiosum_virus R-HSA-69473 G2/M DNA damage checkpoint 29/1497 95/10654 2.642982229095952e-5 7.180932848864472e-5 2.9628930208115276e-5 6118/9156/7531/51588/5982/11200/545/472/11073/891/983/641/6119/3364/7341/10524/5985/995/84126/1111/7157/5984/672/5983/6117/7465/5884/5810/7529 29 Molluscum_contagiosum_virus R-HSA-5358351 Signaling by Hedgehog 40/1497 149/10654 2.6826769805607426e-5 7.273534240181427e-5 3.001100872329569e-5 8454/57154/84617/5567/1452/10382/5568/6500/409/7277/10381/5705/7278/7316/9978/2778/7415/9861/5566/2932/5701/7846/5576/113457/5698/347733/5708/408/10376/5710/5702/83737/5704/6233/7311/10383/84790/5696/7280/7314 40 Molluscum_contagiosum_virus R-HSA-380108 Chemokine receptors bind chemokines 21/1497 59/10654 2.7024203257872766e-5 7.311767729061191e-5 3.0168762234917846e-5 729230/7852/6351/1230/2919/6367/6349/3576/2920/2921/6352/6348/3627/6364/4283/6363/2833/6347/6356/1234/6387 21 Molluscum_contagiosum_virus R-HSA-8941858 Regulation of RUNX3 expression and activity 20/1497 55/10654 2.9212350470159795e-5 7.887334626943145e-5 3.2543583418511354e-5 57154/1029/5705/7316/865/6714/9861/5701/5698/5708/2033/5710/5702/5704/6233/7311/7040/5696/7314/4193 20 Molluscum_contagiosum_virus R-HSA-452723 Transcriptional regulation of pluripotent stem cells 12/1497 24/10654 2.97171974359806e-5 8.006962136596852e-5 3.303717320818064e-5 63978/79727/2516/6657/5460/6774/57167/4089/79923/2247/4087/2034 12 Molluscum_contagiosum_virus R-HSA-5610783 Degradation of GLI2 by the proteasome 21/1497 60/10654 3.613330053623104e-5 9.695394926491809e-5 4.000374124965756e-5 8454/5567/1452/5568/6500/5705/7316/9978/9861/5566/2932/5701/5698/5708/5710/5702/5704/6233/7311/5696/7314 21 Molluscum_contagiosum_virus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 21/1497 60/10654 3.613330053623104e-5 9.695394926491809e-5 4.000374124965756e-5 8454/5567/1452/5568/6500/5705/7316/9978/9861/5566/2932/5701/5698/5708/5710/5702/5704/6233/7311/5696/7314 21 Molluscum_contagiosum_virus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 11/1497 21/10654 3.686026537181784e-5 9.849670911726994e-5 4.0640292585748155e-5 4790/8737/29110/4615/7098/5970/4792/1660/3661/3551/4791 11 Molluscum_contagiosum_virus R-HSA-389513 CTLA4 inhibitory signaling 11/1497 21/10654 3.686026537181784e-5 9.849670911726994e-5 4.0640292585748155e-5 207/941/5528/6714/5519/4067/2534/942/7525/3932/5781 11 Molluscum_contagiosum_virus R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 20/1497 56/10654 3.9504287743640885e-5 1.053447673163757e-4 4.346583966595099e-5 8841/5465/4209/9611/5469/54205/4208/1387/6604/2101/6648/6256/10498/1385/23054/1386/23373/133522/8648/10891 20 Molluscum_contagiosum_virus R-HSA-9006936 Signaling by TGF-beta family members 30/1497 102/10654 4.253012834427282e-5 1.1318079329399912e-4 4.669902777237781e-5 57154/6497/10273/4086/51592/3726/50848/7316/9611/9612/6667/4609/4089/867/7050/4088/142/3065/9958/9040/4087/6233/7514/7048/1025/7311/387/7040/57530/7314 30 Molluscum_contagiosum_virus R-HSA-392518 Signal amplification 14/1497 32/10654 4.320574370282122e-5 1.1468210583495691e-4 4.7318477716177803e-5 2788/5321/54331/2770/2767/6714/1432/2783/2782/2786/2771/2773/2787/10672 14 Molluscum_contagiosum_virus R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 10/1497 18/10654 4.33597468048834e-5 1.1468210583495691e-4 4.7318477716177803e-5 891/983/6790/5111/1647/2033/995/7157/10498/3276 10 Molluscum_contagiosum_virus R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 10/1497 18/10654 4.33597468048834e-5 1.1468210583495691e-4 4.7318477716177803e-5 5594/4314/5598/2885/1385/6196/1956/3845/3265/5595 10 Molluscum_contagiosum_virus R-HSA-389359 CD28 dependent Vav1 pathway 8/1497 12/10654 4.358047785152171e-5 1.1479735629181329e-4 4.7366030698701394e-5 941/2534/942/2885/7409/3932/5062/5879 8 Molluscum_contagiosum_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 8/1497 12/10654 4.358047785152171e-5 1.1479735629181329e-4 4.7366030698701394e-5 3665/29110/7098/7316/3661/6233/7311/7314 8 Molluscum_contagiosum_virus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 24/1497 75/10654 5.5370429271422845e-5 1.4555796416990672e-4 6.005802940083871e-5 11065/991/5705/8881/7316/891/890/4085/983/9861/5701/5698/5708/5710/5702/8900/7324/9232/5704/6233/701/7311/5696/7314 24 Molluscum_contagiosum_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 19/1497 53/10654 5.776964401900332e-5 1.5155760860046213e-4 6.253351621916405e-5 596/10018/7531/1029/842/207/5594/841/1869/6774/54205/598/836/7157/7161/840/5599/7529/5595 19 Molluscum_contagiosum_virus R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 13/1497 29/10654 5.948536617900225e-5 1.5542950517739298e-4 6.413108238313486e-5 5434/5440/5430/5436/5441/5438/5431/5435/5433/5437/3320/5439/5432 13 Molluscum_contagiosum_virus R-HSA-933541 TRAF6 mediated IRF7 activation 13/1497 29/10654 5.948536617900225e-5 1.5542950517739298e-4 6.413108238313486e-5 3665/7186/29110/57506/7706/23586/1387/2033/64135/3661/7189/3439/3456 13 Molluscum_contagiosum_virus R-HSA-198753 ERK/MAPK targets 11/1497 22/10654 6.438295066030839e-5 1.678879357258746e-4 6.927150044569874e-5 5594/5528/4205/5519/5598/1432/4208/2002/6196/5600/5595 11 Molluscum_contagiosum_virus R-HSA-1980145 Signaling by NOTCH2 14/1497 33/10654 6.54001731494486e-5 1.6985696272882843e-4 7.008393199012739e-5 2208/55534/3280/84441/10046/7316/2033/9794/6233/1385/7311/388585/3516/7314 14 Molluscum_contagiosum_virus R-HSA-5654726 Negative regulation of FGFR1 signaling 14/1497 33/10654 6.54001731494486e-5 1.6985696272882843e-4 7.008393199012739e-5 10253/5594/2260/7316/6714/8569/867/2247/6233/2885/7311/5781/7314/5595 14 Molluscum_contagiosum_virus R-HSA-8853659 RET signaling 16/1497 41/10654 6.784240988638032e-5 1.758475264254978e-4 7.255567204690781e-5 5295/6464/5290/5335/5567/5568/6714/5566/8503/5598/5979/2885/9846/5296/5781/9046 16 Molluscum_contagiosum_virus R-HSA-1169091 Activation of NF-kappaB in B cells 22/1497 67/10654 7.241041057013234e-5 1.87313157882019e-4 7.728645565632363e-5 8454/4790/6885/5966/6500/5705/7316/5970/4792/9861/5701/23291/5698/5708/5710/5702/5704/6233/7311/3551/5696/7314 22 Molluscum_contagiosum_virus R-HSA-74751 Insulin receptor signalling cascade 19/1497 54/10654 7.752127842954548e-5 2.0013461522846803e-4 8.257666060433866e-5 5295/54106/6464/5290/3667/5594/2322/2260/2263/2261/2247/3630/2885/9846/5296/3845/3265/5781/5595 19 Molluscum_contagiosum_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 12/1497 26/10654 8.081885677027853e-5 2.082330782788886e-4 8.591813171351154e-5 57154/10273/7316/4088/9958/4087/6233/7514/7048/7311/7040/7314 12 Molluscum_contagiosum_virus R-HSA-174437 Removal of the Flap Intermediate from the C-strand 7/1497 10/10654 8.671677255387186e-5 2.221046190312607e-4 9.164160694272291e-5 6118/2237/5425/5111/6119/6117/5424 7 Molluscum_contagiosum_virus R-HSA-8877330 RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) 7/1497 10/10654 8.671677255387186e-5 2.221046190312607e-4 9.164160694272291e-5 4773/865/3558/50943/3458/861/3559 7 Molluscum_contagiosum_virus R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 7/1497 10/10654 8.671677255387186e-5 2.221046190312607e-4 9.164160694272291e-5 2308/2309/4303/8850/1387/2033/23411 7 Molluscum_contagiosum_virus R-HSA-525793 Myogenesis 13/1497 30/10654 9.155125505141962e-5 2.3402450995392473e-4 9.655982054629123e-5 6925/25/9043/1499/4209/4205/1432/4208/1000/4654/5600/6300/4656 13 Molluscum_contagiosum_virus R-HSA-156711 Polo-like kinase mediated events 9/1497 16/10654 9.374214028033742e-5 2.3915317677818365e-4 9.867593713719728e-5 2305/9133/891/993/5928/2033/995/5347/7465 9 Molluscum_contagiosum_virus R-HSA-186712 Regulation of beta-cell development 16/1497 42/10654 9.542851365598456e-5 2.429771192498153e-4 1.00253717169352e-4 2308/3172/3171/207/55534/3280/6927/84441/10046/8850/1387/2033/3630/9794/3516/4851 16 Molluscum_contagiosum_virus R-HSA-5654727 Negative regulation of FGFR2 signaling 14/1497 34/10654 9.690765350604581e-5 2.462594489094811e-4 1.0160802472873328e-4 10253/5594/7316/2263/6714/8569/867/2247/6233/2885/7311/5781/7314/5595 14 Molluscum_contagiosum_virus R-HSA-171007 p38MAPK events 8/1497 13/10654 9.932092164000415e-5 2.514060829012605e-4 1.037315546733596e-4 9261/6714/1432/5603/3845/5600/3265/6300 8 Molluscum_contagiosum_virus R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 8/1497 13/10654 9.932092164000415e-5 2.514060829012605e-4 1.037315546733596e-4 7531/11200/891/983/995/1111/7465/7529 8 Molluscum_contagiosum_virus R-HSA-389948 PD-1 signaling 11/1497 23/10654 1.0778882092827129e-4 2.7230860023984326e-4 1.123560501314493e-4 5777/919/920/29126/915/917/1445/916/3932/3127/5781 11 Molluscum_contagiosum_virus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 20/1497 60/10654 1.204834179878957e-4 3.031971062375006e-4 1.2510082031241907e-4 8454/6500/5705/7316/5970/9861/5701/23291/5698/5708/5710/5702/9040/5704/6233/7311/5971/5696/4791/7314 20 Molluscum_contagiosum_virus R-HSA-5610780 Degradation of GLI1 by the proteasome 20/1497 60/10654 1.204834179878957e-4 3.031971062375006e-4 1.2510082031241907e-4 8454/5567/5568/6500/5705/7316/9978/9861/5566/5701/5698/5708/5710/5702/83737/5704/6233/7311/5696/7314 20 Molluscum_contagiosum_virus R-HSA-1368108 BMAL1:CLOCK,NPAS2 activates circadian gene expression 12/1497 27/10654 1.2697416878103631e-4 3.182950149714179e-4 1.313303018238144e-4 10135/28999/5465/406/5469/8553/1387/6604/6256/10498/23054/8648 12 Molluscum_contagiosum_virus R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 12/1497 27/10654 1.2697416878103631e-4 3.182950149714179e-4 1.313303018238144e-4 7186/842/8737/356/841/7099/9500/836/1630/8772/8717/8795 12 Molluscum_contagiosum_virus R-HSA-5654733 Negative regulation of FGFR4 signaling 13/1497 31/10654 1.3752926463567777e-4 3.440886621000741e-4 1.4197290476513779e-4 10253/5594/7316/6714/8569/867/2247/6233/2885/7311/5781/7314/5595 13 Molluscum_contagiosum_virus R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 15/1497 39/10654 1.385162507607485e-4 3.458902909170136e-4 1.4271626688258846e-4 10694/9134/8841/10575/7203/10576/908/6774/6950/55294/7157/10574/6468/22948/10693 15 Molluscum_contagiosum_virus R-HSA-8876384 Listeria monocytogenes entry into host cells 10/1497 20/10654 1.3994848516231094e-4 3.487946860968365e-4 1.43914636563672e-4 1499/7316/4233/6714/867/999/6233/2885/7311/7314 10 Molluscum_contagiosum_virus R-HSA-5619115 Disorders of transmembrane transporters 43/1497 176/10654 1.500871875078846e-4 3.733454798660623e-4 1.5404443126377487e-4 23165/5903/55706/7175/9631/1080/348995/79023/57122/5705/23636/10762/23511/26503/7316/335/53371/23279/4927/9688/7415/9861/79902/9883/5701/23225/5698/5708/5710/5702/8086/6520/5704/6233/7311/9972/8021/129401/213/55746/5696/8480/7314 43 Molluscum_contagiosum_virus R-HSA-5260271 Diseases of Immune System 11/1497 24/10654 1.7384942542174802e-4 4.30515458248171e-4 1.776330838125982e-4 4790/7099/4615/7098/5970/4792/114609/695/7097/3551/4791 11 Molluscum_contagiosum_virus R-HSA-5602358 Diseases associated with the TLR signaling cascade 11/1497 24/10654 1.7384942542174802e-4 4.30515458248171e-4 1.776330838125982e-4 4790/7099/4615/7098/5970/4792/114609/695/7097/3551/4791 11 Molluscum_contagiosum_virus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 9/1497 17/10654 1.7439862313293965e-4 4.30515458248171e-4 1.776330838125982e-4 4790/8737/4615/7098/5970/4792/1660/3551/4791 9 Molluscum_contagiosum_virus R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 9/1497 17/10654 1.7439862313293965e-4 4.30515458248171e-4 1.776330838125982e-4 2308/2309/4303/1027/1026/4089/1647/4088/4087 9 Molluscum_contagiosum_virus R-HSA-69541 Stabilization of p53 19/1497 57/10654 1.7699375931654325e-4 4.360910875936123e-4 1.799336196373904e-4 1029/11200/472/5705/7316/9861/4194/5701/5698/5708/5710/5702/7157/5704/6233/7311/5696/7314/4193 19 Molluscum_contagiosum_virus R-HSA-1632852 Macroautophagy 27/1497 95/10654 1.904277085017228e-4 4.683003988960773e-4 1.932233614678422e-4 65018/389541/7249/58528/1460/10533/153129/7316/1457/8678/6714/64223/10325/8649/6009/55054/10542/6233/2475/55004/7311/10670/3312/64121/57521/7314/28956 27 Molluscum_contagiosum_virus R-HSA-2428924 IGF1R signaling cascade 18/1497 53/10654 1.9934305604480464e-4 4.89296592109975e-4 2.0188650811555177e-4 5295/54106/6464/5290/3667/2322/2260/2263/2261/2247/2885/9846/3479/5296/3845/3265/5781/3480 18 Molluscum_contagiosum_virus R-HSA-190861 Gap junction assembly 14/1497 36/10654 2.0086806561843193e-4 4.911792698895996e-4 2.0266331148791145e-4 84617/51807/10382/7277/10381/7278/112714/7846/113457/347733/10376/10383/84790/7280 14 Molluscum_contagiosum_virus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 14/1497 36/10654 2.0086806561843193e-4 4.911792698895996e-4 2.0266331148791145e-4 5604/8844/5594/409/6714/5605/2335/408/1445/60/3845/3265/7529/5595 14 Molluscum_contagiosum_virus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 13/1497 32/10654 2.0206641053710544e-4 4.922520076242268e-4 2.031059290717245e-4 3726/7316/6667/4609/4089/7050/4088/3065/4087/6233/1025/7311/7314 13 Molluscum_contagiosum_virus R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 13/1497 32/10654 2.0206641053710544e-4 4.922520076242268e-4 2.031059290717245e-4 2788/54331/5594/409/2767/6714/408/2783/2782/2786/5595/2787/10672 13 Molluscum_contagiosum_virus R-HSA-3371568 Attenuation phase 8/1497 14/10654 2.031923472606924e-4 4.931409776214558e-4 2.0347272306018478e-4 1387/3320/2033/3326/3312/3297/2288/10728 8 Molluscum_contagiosum_virus R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 8/1497 14/10654 2.031923472606924e-4 4.931409776214558e-4 2.0347272306018478e-4 1017/9134/1027/1869/890/1026/7157/8900 8 Molluscum_contagiosum_virus R-HSA-3371378 Regulation by c-FLIP 7/1497 11/10654 2.0946129518849843e-4 5.017778901373271e-4 2.0703636142768207e-4 7186/8737/356/841/8772/8717/8795 7 Molluscum_contagiosum_virus R-HSA-376172 DSCAM interactions 7/1497 11/10654 2.0946129518849843e-4 5.017778901373271e-4 2.0703636142768207e-4 1432/5603/1630/5599/5600/6300/5879 7 Molluscum_contagiosum_virus R-HSA-4755510 SUMOylation of immune response proteins 7/1497 11/10654 2.0946129518849843e-4 5.017778901373271e-4 2.0703636142768207e-4 51588/5970/4792/7341/10401/7329/4791 7 Molluscum_contagiosum_virus R-HSA-5218900 CASP8 activity is inhibited 7/1497 11/10654 2.0946129518849843e-4 5.017778901373271e-4 2.0703636142768207e-4 7186/8737/356/841/8772/8717/8795 7 Molluscum_contagiosum_virus R-HSA-69416 Dimerization of procaspase-8 7/1497 11/10654 2.0946129518849843e-4 5.017778901373271e-4 2.0703636142768207e-4 7186/8737/356/841/8772/8717/8795 7 Molluscum_contagiosum_virus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 7/1497 11/10654 2.0946129518849843e-4 5.017778901373271e-4 2.0703636142768207e-4 6885/7098/7316/7189/6233/7311/7314 7 Molluscum_contagiosum_virus R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 7/1497 11/10654 2.0946129518849843e-4 5.017778901373271e-4 2.0703636142768207e-4 627/4915/4909/2885/3845/3265/5781 7 Molluscum_contagiosum_virus R-HSA-141424 Amplification of signal from the kinetochores 27/1497 96/10654 2.3008987331796026e-4 5.491647805157947e-4 2.2658845719787502e-4 5905/11130/5903/10403/55143/1058/991/79019/9212/3619/348995/79023/57122/6232/332/1780/5528/4085/23279/79902/5519/699/11004/701/7514/5347/55746 27 Molluscum_contagiosum_virus R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 27/1497 96/10654 2.3008987331796026e-4 5.491647805157947e-4 2.2658845719787502e-4 5905/11130/5903/10403/55143/1058/991/79019/9212/3619/348995/79023/57122/6232/332/1780/5528/4085/23279/79902/5519/699/11004/701/7514/5347/55746 27 Molluscum_contagiosum_virus R-HSA-6807004 Negative regulation of MET activity 10/1497 21/10654 2.3366504860821365e-4 5.566726158019208e-4 2.2968623199104594e-4 5770/3082/7316/4233/867/5771/6233/2885/7311/7314 10 Molluscum_contagiosum_virus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 22/1497 72/10654 2.3724466194356168e-4 5.631301865913112e-4 2.3235066178393937e-4 11065/991/9212/5705/8881/7316/6790/9861/5701/6502/5698/5708/5710/5702/7324/9232/5704/6233/7311/5347/5696/7314 22 Molluscum_contagiosum_virus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 22/1497 72/10654 2.3724466194356168e-4 5.631301865913112e-4 2.3235066178393937e-4 11065/991/5705/8881/7316/890/4085/983/9861/5701/5698/5708/5710/5702/8900/7324/5704/6233/701/7311/5696/7314 22 Molluscum_contagiosum_virus R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 18/1497 54/10654 2.602539448524336e-4 6.154910812568503e-4 2.5395505951793365e-4 5295/54106/6464/5290/3667/2322/2260/2263/2261/2247/2885/9846/3479/5296/3845/3265/5781/3480 18 Molluscum_contagiosum_virus R-HSA-9604323 Negative regulation of NOTCH4 signaling 18/1497 54/10654 2.602539448524336e-4 6.154910812568503e-4 2.5395505951793365e-4 8454/207/6500/5705/7316/9978/9861/5701/5698/5708/55294/5710/5702/5704/6233/7311/5696/7314 18 Molluscum_contagiosum_virus R-HSA-69618 Mitotic Spindle Checkpoint 30/1497 112/10654 2.7295174754790765e-4 6.443451089655525e-4 2.6586039258812594e-4 5905/11130/5903/10403/11065/55143/1058/991/79019/9212/3619/348995/79023/57122/6232/332/1780/8881/5528/4085/23279/79902/5519/699/7324/11004/701/7514/5347/55746 30 Molluscum_contagiosum_virus R-HSA-193704 p75 NTR receptor-mediated signalling 27/1497 97/10654 2.769103971855704e-4 6.525015904590896e-4 2.6922580243113835e-4 8841/4790/10018/7531/835/7074/4615/9500/7316/5970/4792/836/4803/11108/3066/3065/3654/7189/6233/7409/7311/387/5599/3551/7314/5879/10672 27 Molluscum_contagiosum_virus R-HSA-8856688 Golgi-to-ER retrograde transport 34/1497 133/10654 2.9070115616422324e-4 6.837544435369026e-4 2.821209042533679e-4 55582/84617/5321/51807/23095/10382/29127/3832/7277/10381/23299/7278/112714/1780/23303/1639/285643/10112/636/7846/113457/347733/8729/10376/10540/4905/11004/10749/10383/24137/84790/9493/5049/7280 34 Molluscum_contagiosum_virus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 19/1497 59/10654 2.9392049981171803e-4 6.900742169492511e-4 2.8472847807847594e-4 8454/6500/5705/7316/9861/5701/23291/5698/5708/5710/5702/9040/5704/6233/7311/5971/5696/4791/7314 19 Molluscum_contagiosum_virus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 22/1497 73/10654 2.9523078370919726e-4 6.918970988917172e-4 2.854806093542823e-4 11065/991/5705/8881/7316/890/4085/983/9861/5701/5698/5708/5710/5702/8900/7324/5704/6233/701/7311/5696/7314 22 Molluscum_contagiosum_virus R-HSA-210993 Tie2 Signaling 9/1497 18/10654 3.0543749946099674e-4 7.132378365791925e-4 2.942859169771197e-4 5295/6464/5290/2885/5296/3845/3265/5781/9046 9 Molluscum_contagiosum_virus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 9/1497 18/10654 3.0543749946099674e-4 7.132378365791925e-4 2.942859169771197e-4 3665/29110/7099/7316/3661/6233/7311/5781/7314 9 Molluscum_contagiosum_virus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 25/1497 88/10654 3.2681663732104084e-4 7.617884208058794e-4 3.143181593318606e-4 8454/22981/7531/203068/54801/10382/6500/7277/9133/7316/891/983/1639/6790/5566/23291/7846/3320/10540/10733/6233/7311/10383/5347/7314 25 Molluscum_contagiosum_virus R-HSA-8948751 Regulation of PTEN stability and activity 21/1497 69/10654 3.4649175269238887e-4 8.061998410939604e-4 3.3264255951570175e-4 10273/207/1460/5705/7316/1457/4734/9861/5701/5698/5708/5728/5710/5702/8975/5987/5704/6233/7311/5696/7314 21 Molluscum_contagiosum_virus R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 15/1497 42/10654 3.598191261378866e-4 8.357089381267044e-4 3.448181778495499e-4 9070/1499/207/8085/5929/6657/7316/6934/3065/6233/7514/7311/25776/6659/7314 15 Molluscum_contagiosum_virus R-HSA-6806834 Signaling by MET 23/1497 79/10654 3.793682473209979e-4 8.795371172236373e-4 3.6290192945874575e-4 5295/6464/5290/5770/5747/3082/3688/7316/6774/4233/6714/867/2335/5771/3913/6233/2885/7311/3845/3265/5781/7314/5879 23 Molluscum_contagiosum_virus R-HSA-1852241 Organelle biogenesis and maintenance 63/1497 296/10654 3.820746135269419e-4 8.842298198766371e-4 3.6483816479640323e-4 6102/10694/55763/84617/8841/22981/7531/203068/54801/51807/10575/10382/7277/10013/10381/7278/3313/112714/5465/4209/7203/10576/9611/5469/10989/983/1639/54205/5566/1432/4208/1387/6950/55212/7846/113457/6604/347733/3320/8729/2101/10376/10540/10733/6648/6256/117177/10498/1385/23054/10383/1386/5347/84790/22948/56623/5600/6300/23373/133522/8648/7280/10891 63 Molluscum_contagiosum_virus R-HSA-5696394 DNA Damage Recognition in GG-NER 14/1497 38/10654 3.890513135664233e-4 8.98770948987673e-4 3.7083791592408864e-4 9318/83444/8450/7316/9978/10980/1642/142/10987/6233/7311/60/7314/7528 14 Molluscum_contagiosum_virus R-HSA-5619102 SLC transporter disorders 27/1497 99/10654 3.9647504421261163e-4 9.12667242095106e-4 3.765716041133154e-4 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/26503/53371/23279/4927/9688/79902/9883/23225/8086/6520/9972/8021/129401/213/55746/8480 27 Molluscum_contagiosum_virus R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic 27/1497 99/10654 3.9647504421261163e-4 9.12667242095106e-4 3.765716041133154e-4 55582/84617/51807/23095/10382/29127/3832/7277/10381/7278/112714/23303/285643/10112/7846/113457/347733/8729/10376/4905/11004/10749/10383/24137/84790/9493/7280 27 Molluscum_contagiosum_virus R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 26/1497 94/10654 3.9720936854201113e-4 9.127364213305789e-4 3.766001478524481e-4 84617/22981/7531/203068/54801/51807/10382/7277/10381/7278/112714/983/1639/5566/7846/113457/347733/3320/10376/10426/10540/10733/10383/5347/84790/7280 26 Molluscum_contagiosum_virus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 18/1497 56/10654 4.3201210518568136e-4 9.909516607445011e-4 4.0887219270484607e-4 3184/3315/26986/5705/7316/9861/5701/5698/5708/1981/5710/5702/5704/6233/7311/3312/5696/7314 18 Molluscum_contagiosum_virus R-HSA-170968 Frs2-mediated activation 7/1497 12/10654 4.4169443946026507e-4 0.0010095872901948915 4.165613575527981e-4 5604/5594/5605/4914/4803/7529/5595 7 Molluscum_contagiosum_virus R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 7/1497 12/10654 4.4169443946026507e-4 0.0010095872901948915 4.165613575527981e-4 834/835/472/843/7157/7161/839 7 Molluscum_contagiosum_virus R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 19/1497 61/10654 4.730940239635335e-4 0.0010794539701703158 4.453887401287529e-4 26999/25/1072/51517/5747/5594/919/6850/917/3320/695/2885/3326/7409/23191/60/10787/5879/5595 19 Molluscum_contagiosum_virus R-HSA-5696395 Formation of Incision Complex in GG-NER 15/1497 43/10654 4.8167677509121463e-4 0.0010971056248123272 4.526719114722728e-4 6118/8450/7316/9978/6119/7341/10401/1642/142/7329/6233/7311/6117/7314/8554 15 Molluscum_contagiosum_virus R-HSA-2428928 IRS-related events triggered by IGF1R 17/1497 52/10654 4.956942539156404e-4 0.001127052198376614 4.6502803506767384e-4 5295/54106/5290/3667/2322/2260/2263/2261/2247/2885/9846/3479/5296/3845/3265/5781/3480 17 Molluscum_contagiosum_virus R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 9/1497 19/10654 5.083087436475633e-4 0.0011537095127272191 4.760269919309838e-4 7153/4149/1869/993/5111/4609/5928/990/3065 9 Molluscum_contagiosum_virus R-HSA-202733 Cell surface interactions at the vascular wall 34/1497 137/10654 5.236601877611746e-4 0.0011864748310113327 4.895461453490554e-4 5295/5777/6464/5290/5335/960/3684/4312/3678/6383/50848/3688/6714/4067/140885/2335/2534/6520/2885/7525/3685/3932/5296/7040/3687/3845/3265/5781/8795/3689/2207/3676/9046/3655 34 Molluscum_contagiosum_virus R-HSA-8955332 Carboxyterminal post-translational modifications of tubulin 14/1497 39/10654 5.293509487376032e-4 0.0011972754442651549 4.940025387318866e-4 84617/51807/10382/7277/10381/7278/112714/7846/113457/347733/10376/10383/84790/7280 14 Molluscum_contagiosum_virus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 10/1497 23/10654 5.800754963621317e-4 0.0013097174970127575 5.403967580267062e-4 11065/991/8881/7316/891/983/7324/6233/7311/7314 10 Molluscum_contagiosum_virus R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress 11/1497 27/10654 6.061422494028125e-4 0.0013661919221322522 5.636984214125927e-4 5073/1051/1649/3576/468/4800/1054/6347/467/8570/167227 11 Molluscum_contagiosum_virus R-HSA-195721 Signaling by WNT 68/1497 331/10654 6.469041283042943e-4 0.0014555342886846622 6.005615811012088e-4 2788/8454/57154/9070/27161/815/54331/6885/6597/1499/4772/207/8085/1452/5532/57690/5929/6500/27327/409/1460/5705/6657/192670/5530/5528/7316/9978/51699/1457/9559/6934/4609/9861/5519/2932/5701/10524/1387/5698/5708/5880/2033/2783/5710/2782/5702/192669/3065/2786/23112/5704/6233/1855/7474/1857/7514/7311/387/4343/25776/3845/6659/26523/5696/7314/5879/2787 68 Molluscum_contagiosum_virus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 21/1497 72/10654 6.529690118920489e-4 0.0014640966079794038 6.040944418888379e-4 55763/84617/7531/51807/207/10382/7277/10381/7278/112714/7846/113457/347733/10376/9882/10383/60/84790/7280/7529/5879 21 Molluscum_contagiosum_virus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 21/1497 72/10654 6.529690118920489e-4 0.0014640966079794038 6.040944418888379e-4 1017/9134/11065/5705/8881/7316/890/9861/5701/5698/5708/990/5710/5702/8900/7324/5704/6233/7311/5696/7314 21 Molluscum_contagiosum_virus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 27/1497 102/10654 6.608634940742521e-4 0.0014792384945081706 6.10342068884138e-4 8454/7124/7186/356/8600/6500/5705/7316/7133/9861/7132/5701/329/23291/5698/5708/5710/5702/9040/5704/6233/7311/5971/958/5696/4791/7314 27 Molluscum_contagiosum_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 23/1497 82/10654 6.790749757945183e-4 0.0015173813252236134 6.26080013981153e-4 8454/1499/1452/6500/5705/5528/7316/9978/6934/9861/5519/2932/5701/5698/5708/5710/5702/3065/5704/6233/7311/5696/7314 23 Molluscum_contagiosum_virus R-HSA-157858 Gap junction trafficking and regulation 16/1497 49/10654 7.3056122723145e-4 0.0016296167822581053 6.723889907302774e-4 84617/51807/10382/7277/10381/7278/112714/6714/7846/113457/347733/10376/10383/60/84790/7280 16 Molluscum_contagiosum_virus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 17/1497 54/10654 8.081115728286398e-4 0.0017968560872371738 7.413928625052666e-4 8454/6500/5705/7316/9978/6790/9861/5701/5698/5708/5710/5702/5704/6233/7311/5696/7314 17 Molluscum_contagiosum_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 9/1497 20/10654 8.096944096809487e-4 0.0017968560872371738 7.413928625052666e-4 8737/7098/7316/329/7189/6233/7311/3551/7314 9 Molluscum_contagiosum_virus R-HSA-622312 Inflammasomes 9/1497 20/10654 8.096944096809487e-4 0.0017968560872371738 7.413928625052666e-4 834/596/351/4790/29108/5970/598/3326/4791 9 Molluscum_contagiosum_virus R-HSA-1236974 ER-Phagosome pathway 23/1497 83/10654 8.167978446885571e-4 0.001809521379002342 7.46618632661785e-4 5705/7099/4615/7316/567/3106/9861/5701/5698/5708/114609/2923/5710/5702/695/5704/6233/7311/7097/3551/3105/5696/7314 23 Molluscum_contagiosum_virus R-HSA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 7/1497 13/10654 8.411302102505708e-4 0.0018570779429041562 7.662407366758541e-4 5925/5557/5422/1869/5519/23649/5558 7 Molluscum_contagiosum_virus R-HSA-68884 Mitotic Telophase/Cytokinesis 7/1497 13/10654 8.411302102505708e-4 0.0018570779429041562 7.662407366758541e-4 23244/5885/10112/8243/9126/5347/9493 7 Molluscum_contagiosum_virus R-HSA-449836 Other interleukin signaling 10/1497 24/10654 8.702369756052643e-4 0.0019148168427579328 7.900641294030458e-4 1435/920/1441/1440/836/163702/3716/282618/3588/7297 10 Molluscum_contagiosum_virus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 10/1497 24/10654 8.702369756052643e-4 0.0019148168427579328 7.900641294030458e-4 6885/7316/9261/1432/3654/7189/6233/7311/5600/7314 10 Molluscum_contagiosum_virus R-HSA-202040 G-protein activation 11/1497 28/10654 8.728371257975675e-4 0.0019172829068366906 7.910816412224162e-4 2788/54331/2770/5443/4988/2783/2782/2786/2771/2773/2787 11 Molluscum_contagiosum_virus R-HSA-74749 Signal attenuation 6/1497 10/10654 9.629694210602204e-4 0.0021045672338854057 8.683562011158108e-4 6464/3667/5594/3630/2885/5595 6 Molluscum_contagiosum_virus R-HSA-8853334 Signaling by FGFR3 fusions in cancer 6/1497 10/10654 9.629694210602204e-4 0.0021045672338854057 8.683562011158108e-4 5295/5290/2261/2885/3845/3265 6 Molluscum_contagiosum_virus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 6/1497 10/10654 9.629694210602204e-4 0.0021045672338854057 8.683562011158108e-4 6885/7316/7189/6233/7311/7314 6 Molluscum_contagiosum_virus R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 28/1497 110/10654 0.0010327588769159567 0.00225329209508936 9.297209099296581e-4 1017/3725/1019/11065/4790/1029/5594/1027/1051/3576/3490/8881/7316/890/6774/5970/1026/5598/3552/8900/7324/6233/2353/6196/7311/3569/7314/5595 28 Molluscum_contagiosum_virus R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 8/1497 17/10654 0.001110503745699451 0.0024107417997093613 9.946855378917768e-4 7186/8737/356/841/7099/8772/8717/8795 8 Molluscum_contagiosum_virus R-HSA-180292 GAB1 signalosome 8/1497 17/10654 0.001110503745699451 0.0024107417997093613 9.946855378917768e-4 5295/5290/1950/6714/1445/2885/1956/5781 8 Molluscum_contagiosum_virus R-HSA-9022699 MECP2 regulates neuronal receptors and channels 8/1497 17/10654 0.001110503745699451 0.0024107417997093613 9.946855378917768e-4 5770/4233/2289/4988/3066/3065/1385/25942 8 Molluscum_contagiosum_virus R-HSA-1592230 Mitochondrial biogenesis 25/1497 95/10654 0.0011279905345499097 0.0024446082487904397 0.0010086590240298435 8841/3313/5465/4209/9611/5469/10989/54205/1432/4208/1387/6604/2101/6648/6256/10498/1385/23054/1386/5600/6300/23373/133522/8648/10891 25 Molluscum_contagiosum_virus R-HSA-5218920 VEGFR2 mediated vascular permeability 11/1497 29/10654 0.0012296796335194342 0.002660542245477774 0.0010977545977117523 1499/207/64223/3320/4846/79109/2475/7409/5062/5879/253260 11 Molluscum_contagiosum_virus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 10/1497 25/10654 0.0012695515802667837 0.002733121010009554 0.0011277010015309078 11065/991/8881/7316/4085/7324/6233/701/7311/7314 10 Molluscum_contagiosum_virus R-HSA-418592 ADP signalling through P2Y purinoceptor 1 10/1497 25/10654 0.0012695515802667837 0.002733121010009554 0.0011277010015309078 2788/5321/54331/2767/6714/1432/2783/2782/2786/2787 10 Molluscum_contagiosum_virus R-HSA-5654708 Downstream signaling of activated FGFR3 10/1497 25/10654 0.0012695515802667837 0.002733121010009554 0.0011277010015309078 5295/6464/5290/5335/2261/2247/2885/3845/3265/5781 10 Molluscum_contagiosum_virus R-HSA-190828 Gap junction trafficking 15/1497 47/10654 0.0013811577240422494 0.0029684583919714017 0.0012248025204040546 84617/51807/10382/7277/10381/7278/112714/7846/113457/347733/10376/10383/60/84790/7280 15 Molluscum_contagiosum_virus R-HSA-111996 Ca-dependent events 13/1497 38/10654 0.0013927042293192767 0.0029883190086056003 0.0012329971218093285 818/815/3838/5321/5567/817/5594/5568/5566/5576/816/5580/1385 13 Molluscum_contagiosum_virus R-HSA-72306 tRNA processing 27/1497 107/10654 0.0014473446910348966 0.003100427635671448 0.0012792537678046586 23165/5903/55706/7175/9631/3028/348995/79023/57122/23636/10762/23511/53371/283742/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480/54517 27 Molluscum_contagiosum_virus R-HSA-169893 Prolonged ERK activation events 7/1497 14/10654 0.001479068073240452 0.0031631554833657194 0.0013051356282892993 5604/5594/5605/4914/4803/7529/5595 7 Molluscum_contagiosum_virus R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 16/1497 52/10654 0.0014975053762251293 0.003181585192766832 0.0013127398293742288 11200/5705/7316/993/9861/5701/5698/5708/5710/1111/5702/5704/6233/7311/5696/7314 16 Molluscum_contagiosum_virus R-HSA-69610 p53-Independent DNA Damage Response 16/1497 52/10654 0.0014975053762251293 0.003181585192766832 0.0013127398293742288 11200/5705/7316/993/9861/5701/5698/5708/5710/1111/5702/5704/6233/7311/5696/7314 16 Molluscum_contagiosum_virus R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 16/1497 52/10654 0.0014975053762251293 0.003181585192766832 0.0013127398293742288 11200/5705/7316/993/9861/5701/5698/5708/5710/1111/5702/5704/6233/7311/5696/7314 16 Molluscum_contagiosum_virus R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 16/1497 52/10654 0.0014975053762251293 0.003181585192766832 0.0013127398293742288 1019/5705/7316/9861/2932/5701/5698/5708/595/5710/5702/5704/6233/7311/5696/7314 16 Molluscum_contagiosum_virus R-HSA-2172127 DAP12 interactions 14/1497 43/10654 0.0015939341872260536 0.0033809144134942155 0.00139498417970684 5295/6464/5290/5335/567/6850/2534/695/2885/3932/5296/3845/3265/5879 14 Molluscum_contagiosum_virus R-HSA-112399 IRS-mediated signalling 15/1497 48/10654 0.0017523212266981507 0.003710797891831378 0.001531095946272206 5295/54106/5290/3667/2322/2260/2263/2261/2247/2885/9846/5296/3845/3265/5781 15 Molluscum_contagiosum_virus R-HSA-1250196 SHC1 events in ERBB2 signaling 9/1497 22/10654 0.0018419354075844456 0.003881541932080393 0.0016015458914041907 6464/2064/1950/2885/5580/1956/5581/3845/3265 9 Molluscum_contagiosum_virus R-HSA-202427 Phosphorylation of CD3 and TCR zeta chains 9/1497 22/10654 0.0018419354075844456 0.003881541932080393 0.0016015458914041907 5788/919/920/915/917/1445/916/3932/3127 9 Molluscum_contagiosum_virus R-HSA-392170 ADP signalling through P2Y purinoceptor 12 9/1497 22/10654 0.0018419354075844456 0.003881541932080393 0.0016015458914041907 2788/54331/2770/2783/2782/2786/2771/2773/2787 9 Molluscum_contagiosum_virus R-HSA-5655291 Signaling by FGFR4 in disease 6/1497 11/10654 0.0018671791721062876 0.00391563787548503 0.0016156140681825824 5295/5290/5335/2885/3845/3265 6 Molluscum_contagiosum_virus R-HSA-8851805 MET activates RAS signaling 6/1497 11/10654 0.0018671791721062876 0.00391563787548503 0.0016156140681825824 6464/3082/4233/2885/3845/3265 6 Molluscum_contagiosum_virus R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 6/1497 11/10654 0.0018671791721062876 0.00391563787548503 0.0016156140681825824 6885/7316/7189/6233/7311/7314 6 Molluscum_contagiosum_virus R-HSA-1912408 Pre-NOTCH Transcription and Translation 24/1497 93/10654 0.0018733971721296096 0.003922330751340831 0.0016183755861607716 27161/3725/55534/57690/27327/84441/10046/192670/1869/4854/1871/8850/1387/2033/595/192669/7157/861/23112/9794/4343/26523/3516/4851 24 Molluscum_contagiosum_virus R-HSA-186797 Signaling by PDGF 17/1497 58/10654 0.0019516354533624298 0.004079547657351143 0.001683244160115644 5295/5290/5335/6778/6776/6774/6772/6714/5159/2885/5155/5296/3845/6777/3265/5781/5156 17 Molluscum_contagiosum_virus R-HSA-1236975 Antigen processing-Cross presentation 25/1497 99/10654 0.0021082304776947097 0.004399785344754176 0.0018153760194404823 5705/7099/4615/7316/567/3106/9861/5701/5698/5708/114609/2923/5710/5702/695/9902/5704/6233/3685/7311/7097/3551/3105/5696/7314 25 Molluscum_contagiosum_virus R-HSA-73886 Chromosome Maintenance 27/1497 110/10654 0.0022318174782888158 0.0046502177682673715 0.0019187058368094745 6118/2237/1058/79019/4869/5982/5931/54107/3978/5557/5422/5425/5111/5426/6119/5928/5427/5985/5984/23649/11339/5983/6117/5981/5558/5424/56655 27 Molluscum_contagiosum_virus R-HSA-182971 EGFR downregulation 11/1497 31/10654 0.0023025879581784073 0.00478997430786391 0.0019763701660127243 10253/58513/7316/1950/867/6233/2885/7311/1956/10252/7314 11 Molluscum_contagiosum_virus R-HSA-112043 PLC beta mediated events 16/1497 54/10654 0.0023174019996638263 0.004813065691609486 0.0019858977999818216 818/815/3838/5321/5567/2770/817/5594/5568/5566/5576/816/2771/5580/1385/2773 16 Molluscum_contagiosum_virus R-HSA-6783310 Fanconi Anemia Pathway 13/1497 40/10654 0.0023607425405416434 0.004895235732067151 0.0020198016178444717 6118/2176/2178/545/7316/6119/2177/84126/55215/6233/7311/6117/7314 13 Moloney_murine_leukemia_virus R-HSA-9012852 Signaling by NOTCH3 21/38 49/10654 1.4834651848068508e-41 6.186049820644568e-39 1.2180029938414144e-39 7316/3714/11060/388585/57534/182/9794/3516/9148/142678/7311/23462/54567/28514/102/7314/4851/54492/6233/4854/23493 21 Moloney_murine_leukemia_virus R-HSA-2691230 Signaling by NOTCH1 HD Domain Mutants in Cancer 15/38 15/10654 7.899830383638696e-39 1.0980764233257788e-36 2.1620588418379587e-37 7316/3714/57534/182/9148/142678/7311/6868/54567/28514/102/7314/4851/54492/6233 15 Moloney_murine_leukemia_virus R-HSA-2691232 Constitutive Signaling by NOTCH1 HD Domain Mutants 15/38 15/10654 7.899830383638696e-39 1.0980764233257788e-36 2.1620588418379587e-37 7316/3714/57534/182/9148/142678/7311/6868/54567/28514/102/7314/4851/54492/6233 15 Moloney_murine_leukemia_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 20/38 58/10654 4.069428722929204e-37 2.1211897218268474e-35 4.1765189524799725e-36 7316/3714/388585/57534/182/9794/3516/9148/142678/7311/23462/6868/54567/28514/102/7314/4851/54492/6233/23493 20 Moloney_murine_leukemia_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 20/38 58/10654 4.069428722929204e-37 2.1211897218268474e-35 4.1765189524799725e-36 7316/3714/388585/57534/182/9794/3516/9148/142678/7311/23462/6868/54567/28514/102/7314/4851/54492/6233/23493 20 Moloney_murine_leukemia_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 20/38 58/10654 4.069428722929204e-37 2.1211897218268474e-35 4.1765189524799725e-36 7316/3714/388585/57534/182/9794/3516/9148/142678/7311/23462/6868/54567/28514/102/7314/4851/54492/6233/23493 20 Moloney_murine_leukemia_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 20/38 58/10654 4.069428722929204e-37 2.1211897218268474e-35 4.1765189524799725e-36 7316/3714/388585/57534/182/9794/3516/9148/142678/7311/23462/6868/54567/28514/102/7314/4851/54492/6233/23493 20 Moloney_murine_leukemia_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 20/38 58/10654 4.069428722929204e-37 2.1211897218268474e-35 4.1765189524799725e-36 7316/3714/388585/57534/182/9794/3516/9148/142678/7311/23462/6868/54567/28514/102/7314/4851/54492/6233/23493 20 Moloney_murine_leukemia_virus R-HSA-1980145 Signaling by NOTCH2 17/38 33/10654 3.9997105567681e-35 1.8531992246358866e-33 3.648858753542829e-34 7316/4853/3714/388585/57534/182/9794/3516/9148/142678/7311/54567/28514/102/7314/54492/6233 17 Moloney_murine_leukemia_virus R-HSA-1980143 Signaling by NOTCH1 20/38 73/10654 9.24114267259879e-35 3.853556494473696e-33 7.587464510133745e-34 7316/3714/388585/57534/182/9794/3516/9148/142678/7311/23462/6868/54567/28514/102/7314/4851/54492/6233/23493 20 Moloney_murine_leukemia_virus R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus 15/38 25/10654 2.530385256466769e-32 9.592460472242204e-31 1.888708612482373e-31 7316/3714/11060/57534/182/9148/142678/7311/54567/28514/102/7314/54492/6233/4854 15 Moloney_murine_leukemia_virus R-HSA-157118 Signaling by NOTCH 24/38 235/10654 3.953618458736659e-31 1.373882414410989e-29 2.7051073665040302e-30 7316/4853/3714/11060/388585/57534/182/9794/3516/9148/142678/7311/23462/6868/54567/28514/102/7314/4851/54492/6233/4855/4854/23493 24 Moloney_murine_leukemia_virus R-HSA-2979096 NOTCH2 Activation and Transmission of Signal to the Nucleus 14/38 22/10654 1.1011886010124993e-30 3.532274204786248e-29 6.954875374815786e-30 7316/4853/3714/57534/182/9148/142678/7311/54567/28514/102/7314/54492/6233 14 Moloney_murine_leukemia_virus R-HSA-2122948 Activated NOTCH1 Transmits Signal to the Nucleus 15/38 31/10654 2.298339994506456e-30 6.845769840779944e-29 1.3478986433947638e-29 7316/3714/57534/182/9148/142678/7311/6868/54567/28514/102/7314/4851/54492/6233 15 Moloney_murine_leukemia_virus R-HSA-9013694 Signaling by NOTCH4 15/38 82/10654 6.870762623660741e-23 1.910072009377686e-21 3.7608384887406163e-22 7316/4853/388585/182/9794/3516/7311/23462/54567/102/7314/4851/6233/4855/23493 15 Moloney_murine_leukemia_virus R-HSA-5663202 Diseases of signal transduction 21/38 377/10654 3.212241500524305e-21 8.37190441074147e-20 1.648387085795367e-20 7316/3714/388585/57534/182/9794/3516/9148/142678/7311/23462/6469/6868/54567/28514/102/7314/4851/54492/6233/23493 21 Moloney_murine_leukemia_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 10/38 47/10654 4.3324695448890416e-16 1.062729294246312e-14 2.09246207121576e-15 7316/388585/9794/3516/7311/23462/7314/4851/6233/23493 10 Moloney_murine_leukemia_virus R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 8/38 20/10654 1.4557718130504467e-15 3.372538033566868e-14 6.6403626560195814e-15 4853/388585/9794/3516/23462/4851/4855/23493 8 Moloney_murine_leukemia_virus R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 7/38 25/10654 1.8779829083695085e-12 4.1216782778425525e-11 8.115383205142474e-12 388585/9794/3516/23462/4851/4854/23493 7 Moloney_murine_leukemia_virus R-HSA-350054 Notch-HLH transcription pathway 6/38 28/10654 4.84479153099961e-10 1.0101390342134187e-8 1.9889144179893135e-9 4853/9794/3516/4851/4855/4854 6 Moloney_murine_leukemia_virus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 6/38 32/10654 1.1533735981827653e-9 2.2902704306772055e-8 4.509430609436376e-9 7316/23439/7311/7314/6233/1025 6 Moloney_murine_leukemia_virus R-HSA-8878159 Transcriptional regulation by RUNX3 8/38 96/10654 1.265833968190302e-9 2.399330748797072e-8 4.724165048748496e-9 7316/182/9794/3516/7311/7314/4851/6233 8 Moloney_murine_leukemia_virus R-HSA-901032 ER Quality Control Compartment (ERQC) 5/38 21/10654 8.575385812783914e-9 1.5134472736722838e-7 2.979903757325209e-8 10206/7316/7311/7314/6233 5 Moloney_murine_leukemia_virus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 6/38 44/10654 8.710487906027533e-9 1.5134472736722838e-7 2.979903757325209e-8 7316/23439/7311/7314/6233/1025 6 Moloney_murine_leukemia_virus R-HSA-177929 Signaling by EGFR 6/38 49/10654 1.7033928123184193e-8 2.8412592109471233e-7 5.594300604666809e-8 7316/7311/6868/102/7314/6233 6 Moloney_murine_leukemia_virus R-HSA-901042 Calnexin/calreticulin cycle 5/38 26/10654 2.736459285319848e-8 4.3888596999168333e-7 8.641450374694258e-8 10206/7316/7311/7314/6233 5 Moloney_murine_leukemia_virus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 4/38 10/10654 2.8451545243132492e-8 4.3941830986615737e-7 8.651931886800524e-8 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-9013700 NOTCH4 Activation and Transmission of Signal to the Nucleus 4/38 11/10654 4.4595402939342114e-8 6.198761008568554e-7 1.2205057646556788e-7 182/54567/102/4855 4 Moloney_murine_leukemia_virus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 4/38 11/10654 4.4595402939342114e-8 6.198761008568554e-7 1.2205057646556788e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 4/38 11/10654 4.4595402939342114e-8 6.198761008568554e-7 1.2205057646556788e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-2197563 NOTCH2 intracellular domain regulates transcription 4/38 12/10654 6.672229443245922e-8 8.431271751010756e-7 1.6600762251138181e-7 4853/388585/9794/3516 4 Moloney_murine_leukemia_virus R-HSA-5689877 Josephin domain DUBs 4/38 12/10654 6.672229443245922e-8 8.431271751010756e-7 1.6600762251138181e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 4/38 12/10654 6.672229443245922e-8 8.431271751010756e-7 1.6600762251138181e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5656169 Termination of translesion DNA synthesis 5/38 32/10654 8.248292705594255e-8 1.0116288406567072e-6 1.9918477741063533e-7 7316/7311/7314/7706/6233 5 Moloney_murine_leukemia_virus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 4/38 13/10654 9.613055916452516e-8 1.059420389644874e-6 2.0859469996794194e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-209543 p75NTR recruits signalling complexes 4/38 13/10654 9.613055916452516e-8 1.059420389644874e-6 2.0859469996794194e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-209560 NF-kB is activated and signals survival 4/38 13/10654 9.613055916452516e-8 1.059420389644874e-6 2.0859469996794194e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5358346 Hedgehog ligand biogenesis 6/38 65/10654 9.654190601080389e-8 1.059420389644874e-6 2.0859469996794194e-7 7316/7311/6469/6868/7314/6233 6 Moloney_murine_leukemia_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 5/38 34/10654 1.1338473528562754e-7 1.2123444772847868e-6 2.3870470586447903e-7 7316/7311/7314/7706/6233 5 Moloney_murine_leukemia_virus R-HSA-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle 5/38 35/10654 1.3194052902736312e-7 1.3018075601185739e-6 2.5631954989082107e-7 10206/7316/7311/7314/6233 5 Moloney_murine_leukemia_virus R-HSA-174490 Membrane binding and targetting of GAG proteins 4/38 14/10654 1.3423914888512873e-7 1.3018075601185739e-6 2.5631954989082107e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-174495 Synthesis And Processing Of GAG, GAGPOL Polyproteins 4/38 14/10654 1.3423914888512873e-7 1.3018075601185739e-6 2.5631954989082107e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-8941856 RUNX3 regulates NOTCH signaling 4/38 14/10654 1.3423914888512873e-7 1.3018075601185739e-6 2.5631954989082107e-7 182/9794/3516/4851 4 Moloney_murine_leukemia_virus R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 4/38 15/10654 1.8258600326033238e-7 1.5862159033241374e-6 3.1231816347162116e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 4/38 15/10654 1.8258600326033238e-7 1.5862159033241374e-6 3.1231816347162116e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-937039 IRAK1 recruits IKK complex 4/38 15/10654 1.8258600326033238e-7 1.5862159033241374e-6 3.1231816347162116e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 4/38 15/10654 1.8258600326033238e-7 1.5862159033241374e-6 3.1231816347162116e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 4/38 15/10654 1.8258600326033238e-7 1.5862159033241374e-6 3.1231816347162116e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 6/38 73/10654 1.9489577737683586e-7 1.6586028401253173e-6 3.265707977528077e-7 7316/23439/7311/7314/6233/1025 6 Moloney_murine_leukemia_virus R-HSA-5689896 Ovarian tumor domain proteases 5/38 38/10654 2.0242815703680007e-7 1.6599774552152974e-6 3.268414527496988e-7 7316/7311/7314/7706/6233 5 Moloney_murine_leukemia_virus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 5/38 39/10654 2.3159726738725658e-7 1.6599774552152974e-6 3.268414527496988e-7 7316/7311/7314/7706/6233 5 Moloney_murine_leukemia_virus R-HSA-110312 Translesion synthesis by REV1 4/38 16/10654 2.428264382928852e-7 1.6599774552152974e-6 3.268414527496988e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-1295596 Spry regulation of FGF signaling 4/38 16/10654 2.428264382928852e-7 1.6599774552152974e-6 3.268414527496988e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-175474 Assembly Of The HIV Virion 4/38 16/10654 2.428264382928852e-7 1.6599774552152974e-6 3.268414527496988e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-193639 p75NTR signals via NF-kB 4/38 16/10654 2.428264382928852e-7 1.6599774552152974e-6 3.268414527496988e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-205043 NRIF signals cell death from the nucleus 4/38 16/10654 2.428264382928852e-7 1.6599774552152974e-6 3.268414527496988e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 4/38 16/10654 2.428264382928852e-7 1.6599774552152974e-6 3.268414527496988e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-3229121 Glycogen storage diseases 4/38 16/10654 2.428264382928852e-7 1.6599774552152974e-6 3.268414527496988e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-3322077 Glycogen synthesis 4/38 16/10654 2.428264382928852e-7 1.6599774552152974e-6 3.268414527496988e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 4/38 16/10654 2.428264382928852e-7 1.6599774552152974e-6 3.268414527496988e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 4/38 16/10654 2.428264382928852e-7 1.6599774552152974e-6 3.268414527496988e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5655862 Translesion synthesis by POLK 4/38 17/10654 3.167315474759502e-7 2.063703989022988e-6 4.063332352487519e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5656121 Translesion synthesis by POLI 4/38 17/10654 3.167315474759502e-7 2.063703989022988e-6 4.063332352487519e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 4/38 17/10654 3.167315474759502e-7 2.063703989022988e-6 4.063332352487519e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-75893 TNF signaling 5/38 43/10654 3.8321842957069155e-7 2.4584936173996673e-6 4.840653847208736e-7 7316/7311/6868/7314/6233 5 Moloney_murine_leukemia_virus R-HSA-1912420 Pre-NOTCH Processing in Golgi 4/38 18/10654 4.061866156030845e-7 2.490879686860092e-6 4.904420436074396e-7 4853/4851/4855/4854 4 Moloney_murine_leukemia_virus R-HSA-5675482 Regulation of necroptotic cell death 4/38 18/10654 4.061866156030845e-7 2.490879686860092e-6 4.904420436074396e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 4/38 18/10654 4.061866156030845e-7 2.490879686860092e-6 4.904420436074396e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-110320 Translesion Synthesis by POLH 4/38 19/10654 5.131895451574888e-7 2.972222782370456e-6 5.852161479866102e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 4/38 19/10654 5.131895451574888e-7 2.972222782370456e-6 5.852161479866102e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 4/38 19/10654 5.131895451574888e-7 2.972222782370456e-6 5.852161479866102e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-6804760 Regulation of TP53 Activity through Methylation 4/38 19/10654 5.131895451574888e-7 2.972222782370456e-6 5.852161479866102e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 4/38 20/10654 6.398492952040254e-7 3.5107520539484024e-6 6.912499311068419e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5213460 RIPK1-mediated regulated necrosis 4/38 20/10654 6.398492952040254e-7 3.5107520539484024e-6 6.912499311068419e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5218859 Regulated Necrosis 4/38 20/10654 6.398492952040254e-7 3.5107520539484024e-6 6.912499311068419e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-8876384 Listeria monocytogenes entry into host cells 4/38 20/10654 6.398492952040254e-7 3.5107520539484024e-6 6.912499311068419e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-73893 DNA Damage Bypass 5/38 48/10654 6.729243255007727e-7 3.6442784900496396e-6 7.175406341635034e-7 7316/7311/7314/7706/6233 5 Moloney_murine_leukemia_virus R-HSA-4641263 Regulation of FZD by ubiquitination 4/38 21/10654 7.883843327078505e-7 4.161471730875616e-6 8.193734570448014e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-6807004 Negative regulation of MET activity 4/38 21/10654 7.883843327078505e-7 4.161471730875616e-6 8.193734570448014e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-1912408 Pre-NOTCH Transcription and Translation 6/38 93/10654 8.287253389679396e-7 4.319730829370386e-6 8.505339005197274e-7 4853/9794/3516/4851/4855/4854 6 Moloney_murine_leukemia_virus R-HSA-5205685 Pink/Parkin Mediated Mitophagy 4/38 22/10654 9.611210962038987e-7 4.828765025506335e-6 9.507602473545225e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-912631 Regulation of signaling by CBL 4/38 22/10654 9.611210962038987e-7 4.828765025506335e-6 9.507602473545225e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-9613829 Chaperone Mediated Autophagy 4/38 22/10654 9.611210962038987e-7 4.828765025506335e-6 9.507602473545225e-7 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 4/38 23/10654 1.1604924717419253e-6 5.627039078097475e-6 1.107936509129378e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 4/38 23/10654 1.1604924717419253e-6 5.627039078097475e-6 1.107936509129378e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 4/38 23/10654 1.1604924717419253e-6 5.627039078097475e-6 1.107936509129378e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-9604323 Negative regulation of NOTCH4 signaling 5/38 54/10654 1.2237080690900809e-6 5.865359365638663e-6 1.1548606096675902e-6 7316/7311/7314/6233/4855 5 Moloney_murine_leukemia_virus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 4/38 24/10654 1.3890362810320074e-6 6.5821378317084894e-6 1.2959907885226865e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-9006936 Signaling by TGF-beta family members 6/38 102/10654 1.4303155928766684e-6 6.7015910362873115e-6 1.319510541033473e-6 7316/23439/7311/7314/6233/1025 6 Moloney_murine_leukemia_virus R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 5/38 56/10654 1.4704215047923316e-6 6.81295297220447e-6 1.3414371622666884e-6 7316/7311/6469/7314/6233 5 Moloney_murine_leukemia_virus R-HSA-1643713 Signaling by EGFR in Cancer 4/38 25/10654 1.6493937817160838e-6 7.3169915635702865e-6 1.4406798989233434e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 4/38 25/10654 1.6493937817160838e-6 7.3169915635702865e-6 1.4406798989233434e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 4/38 25/10654 1.6493937817160838e-6 7.3169915635702865e-6 1.4406798989233434e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-937041 IKK complex recruitment mediated by RIP1 4/38 25/10654 1.6493937817160838e-6 7.3169915635702865e-6 1.4406798989233434e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-1236394 Signaling by ERBB4 5/38 58/10654 1.7547649502800215e-6 7.702494571229146e-6 1.51658355813675e-6 7316/7311/6868/7314/6233 5 Moloney_murine_leukemia_virus R-HSA-5387390 Hh mutants abrogate ligand secretion 5/38 59/10654 1.9122907836050297e-6 8.306513091284347e-6 1.6355118543990386e-6 7316/7311/6469/7314/6233 5 Moloney_murine_leukemia_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 4/38 26/10654 1.944308179691152e-6 8.358520731249592e-6 1.6457519046761788e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-1912422 Pre-NOTCH Expression and Processing 6/38 109/10654 2.1124095658391934e-6 8.988518254642281e-6 1.769795339800828e-6 4853/9794/3516/4851/4855/4854 6 Moloney_murine_leukemia_virus R-HSA-162588 Budding and maturation of HIV virion 4/38 29/10654 3.0653231337414897e-6 1.2410094628836906e-5 2.4434870151439575e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5205647 Mitophagy 4/38 29/10654 3.0653231337414897e-6 1.2410094628836906e-5 2.4434870151439575e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5654732 Negative regulation of FGFR3 signaling 4/38 29/10654 3.0653231337414897e-6 1.2410094628836906e-5 2.4434870151439575e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-8863795 Downregulation of ERBB2 signaling 4/38 29/10654 3.0653231337414897e-6 1.2410094628836906e-5 2.4434870151439575e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-8982491 Glycogen metabolism 4/38 29/10654 3.0653231337414897e-6 1.2410094628836906e-5 2.4434870151439575e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 4/38 30/10654 3.527884744976315e-6 1.3878565459010599e-5 2.732621748839648e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 4/38 30/10654 3.527884744976315e-6 1.3878565459010599e-5 2.732621748839648e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 4/38 30/10654 3.527884744976315e-6 1.3878565459010599e-5 2.732621748839648e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-8878166 Transcriptional regulation by RUNX2 6/38 121/10654 3.8866429604083505e-6 1.514701041579703e-5 2.9823723650944552e-6 7316/7311/23462/7314/6233/23493 6 Moloney_murine_leukemia_virus R-HSA-182971 EGFR downregulation 4/38 31/10654 4.040197272479739e-6 1.545653451948671e-5 3.043316149236308e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5654733 Negative regulation of FGFR4 signaling 4/38 31/10654 4.040197272479739e-6 1.545653451948671e-5 3.043316149236308e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-8948751 Regulation of PTEN stability and activity 5/38 69/10654 4.183170263107966e-6 1.585801817923656e-5 3.1223663207887213e-6 7316/11060/7311/7314/6233 5 Moloney_murine_leukemia_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 4/38 32/10654 4.6055850361117185e-6 1.7147580000523094e-5 3.376274744517989e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-917729 Endosomal Sorting Complex Required For Transport (ESCRT) 4/38 32/10654 4.6055850361117185e-6 1.7147580000523094e-5 3.376274744517989e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-1169408 ISG15 antiviral mechanism 5/38 72/10654 5.1676416931620855e-6 1.8631218635765632e-5 3.6683959449443884e-6 7316/7311/7314/7706/6233 5 Moloney_murine_leukemia_virus R-HSA-2559585 Oncogene Induced Senescence 4/38 33/10654 5.227464221545753e-6 1.8631218635765632e-5 3.6683959449443884e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 4/38 33/10654 5.227464221545753e-6 1.8631218635765632e-5 3.6683959449443884e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5357905 Regulation of TNFR1 signaling 4/38 33/10654 5.227464221545753e-6 1.8631218635765632e-5 3.6683959449443884e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5654726 Negative regulation of FGFR1 signaling 4/38 33/10654 5.227464221545753e-6 1.8631218635765632e-5 3.6683959449443884e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5654727 Negative regulation of FGFR2 signaling 4/38 34/10654 5.909341486380431e-6 2.070752436824067e-5 4.077210401925464e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5663084 Diseases of carbohydrate metabolism 4/38 34/10654 5.909341486380431e-6 2.070752436824067e-5 4.077210401925464e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-9615710 Microautophagy 4/38 35/10654 6.654812577651805e-6 2.3125473707340023e-5 4.553292816288078e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-168638 NOD1/2 Signaling Pathway 4/38 36/10654 7.467560960676233e-6 2.552436820165565e-5 5.025623424786421e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-6804757 Regulation of TP53 Degradation 4/38 36/10654 7.467560960676233e-6 2.552436820165565e-5 5.025623424786421e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 5/38 78/10654 7.677104516179338e-6 2.6027256774364094e-5 5.1246397283867215e-6 7316/7311/7314/7706/6233 5 Moloney_murine_leukemia_virus R-HSA-5689901 Metalloprotease DUBs 4/38 37/10654 8.351356459153625e-6 2.7860125147736494e-5 5.4855225584335395e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 4/38 37/10654 8.351356459153625e-6 2.7860125147736494e-5 5.4855225584335395e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 5/38 80/10654 8.697108245005271e-6 2.8783286810850777e-5 5.66728858070519e-6 7316/7311/7314/7706/6233 5 Moloney_murine_leukemia_virus R-HSA-6807070 PTEN Regulation 6/38 140/10654 9.0323038375484955e-006 2.9657249608328524e-5 5.839367586645526e-6 7316/11060/7311/7314/1822/6233 6 Moloney_murine_leukemia_virus R-HSA-5696394 DNA Damage Recognition in GG-NER 4/38 38/10654 9.310053906461477e-6 3.033040999214403e-5 5.971909578157856e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5654741 Signaling by FGFR3 4/38 40/10654 1.1467991015009459e-5 3.650497903251102e-5 7.187652062440642e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5675221 Negative regulation of MAPK pathway 4/38 40/10654 1.1467991015009459e-5 3.650497903251102e-5 7.187652062440642e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-6783310 Fanconi Anemia Pathway 4/38 40/10654 1.1467991015009459e-5 3.650497903251102e-5 7.187652062440642e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5632684 Hedgehog 'on' state 5/38 85/10654 1.1714326616157841e-5 3.700662271922591e-5 7.286423254069471e-6 7316/7311/6469/7314/6233 5 Moloney_murine_leukemia_virus R-HSA-5654743 Signaling by FGFR4 4/38 41/10654 1.267535340832169e-5 3.9444943069180186e-5 7.766516620966943e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5696400 Dual Incision in GG-NER 4/38 41/10654 1.267535340832169e-5 3.9444943069180186e-5 7.766516620966943e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5358351 Signaling by Hedgehog 6/38 149/10654 1.290965709897571e-5 3.987649637239164e-5 7.851487358441369e-6 7316/7311/6469/6868/7314/6233 6 Moloney_murine_leukemia_virus R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 4/38 42/10654 1.3973860594426225e-5 4.284632255790983e-5 8.436231628213976e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5696395 Formation of Incision Complex in GG-NER 4/38 43/10654 1.536777261133451e-5 4.6776358970266355e-5 9.210036601491293e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-69231 Cyclin D associated events in G1 4/38 44/10654 1.6861426645643382e-005 5.0584279936930145e-5 9.959797639986247e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-69236 G1 Phase 4/38 44/10654 1.6861426645643382e-005 5.0584279936930145e-5 9.959797639986247e-6 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-193704 p75 NTR receptor-mediated signalling 5/38 97/10654 2.2312035632513984e-5 6.645799184827379e-5 1.308525397997061e-5 7316/7311/6868/7314/6233 5 Moloney_murine_leukemia_virus R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 3/38 16/10654 2.2705756480848415e-5 6.71510670391049e-5 1.3221717099710166e-5 9794/3516/4851 3 Moloney_murine_leukemia_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 4/38 48/10654 2.392283593842426e-5 7.025227173466842e-5 1.3832329156390606e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-1227986 Signaling by ERBB2 4/38 50/10654 2.8170217997763758e-5 8.101366141425853e-5 1.5951194220149353e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 4/38 50/10654 2.8170217997763758e-5 8.101366141425853e-5 1.5951194220149353e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5654736 Signaling by FGFR1 4/38 50/10654 2.8170217997763758e-5 8.101366141425853e-5 1.5951194220149353e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-180534 Vpu mediated degradation of CD4 4/38 52/10654 3.2946295099003616e-5 9.098413944559278e-5 1.7914332643585096e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 4/38 52/10654 3.2946295099003616e-5 9.098413944559278e-5 1.7914332643585096e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 4/38 52/10654 3.2946295099003616e-5 9.098413944559278e-5 1.7914332643585096e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-69610 p53-Independent DNA Damage Response 4/38 52/10654 3.2946295099003616e-5 9.098413944559278e-5 1.7914332643585096e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 4/38 52/10654 3.2946295099003616e-5 9.098413944559278e-5 1.7914332643585096e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 4/38 52/10654 3.2946295099003616e-5 9.098413944559278e-5 1.7914332643585096e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-169911 Regulation of Apoptosis 4/38 53/10654 3.5544908788286965e-5 9.751465108365567e-5 1.9200158486747806e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-180585 Vif-mediated degradation of APOBEC3G 4/38 54/10654 3.8290604845822686e-5 1.0170179758412778e-4 2.0024587180517394e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 4/38 54/10654 3.8290604845822686e-5 1.0170179758412778e-4 2.0024587180517394e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-8848021 Signaling by PTK6 4/38 54/10654 3.8290604845822686e-5 1.0170179758412778e-4 2.0024587180517394e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 4/38 54/10654 3.8290604845822686e-5 1.0170179758412778e-4 2.0024587180517394e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 4/38 54/10654 3.8290604845822686e-5 1.0170179758412778e-4 2.0024587180517394e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-977225 Amyloid fiber formation 5/38 109/10654 3.9211233146638485e-5 1.0348787482372309e-4 2.037625706487543e-5 7316/7311/102/7314/6233 5 Moloney_murine_leukemia_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 4/38 55/10654 4.1188487430676265e-5 1.0602221764562964e-4 2.087525678747725e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 4/38 55/10654 4.1188487430676265e-5 1.0602221764562964e-4 2.087525678747725e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-4641257 Degradation of AXIN 4/38 55/10654 4.1188487430676265e-5 1.0602221764562964e-4 2.087525678747725e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-8941858 Regulation of RUNX3 expression and activity 4/38 55/10654 4.1188487430676265e-5 1.0602221764562964e-4 2.087525678747725e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 4/38 56/10654 4.4243723271128817e-5 1.1318793008626206e-4 2.2286150566019037e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-4641258 Degradation of DVL 4/38 57/10654 4.746154051581773e-5 1.1994825693997572e-4 2.361722590260787e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-69541 Stabilization of p53 4/38 57/10654 4.746154051581773e-5 1.1994825693997572e-4 2.361722590260787e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-917937 Iron uptake and transport 4/38 58/10654 5.084722759474651e-5 1.27730686186803e-4 2.514954820792789e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 4/38 59/10654 5.4406132090102284e-5 1.3424471645900977e-4 2.6432128950656987e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 4/38 59/10654 5.4406132090102284e-5 1.3424471645900977e-4 2.6432128950656987e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 4/38 59/10654 5.4406132090102284e-5 1.3424471645900977e-4 2.6432128950656987e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 4/38 60/10654 5.81436596168192e-5 1.3934428770237704e-4 2.743620961955171e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 4/38 60/10654 5.81436596168192e-5 1.3934428770237704e-4 2.743620961955171e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5610780 Degradation of GLI1 by the proteasome 4/38 60/10654 5.81436596168192e-5 1.3934428770237704e-4 2.743620961955171e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5610783 Degradation of GLI2 by the proteasome 4/38 60/10654 5.81436596168192e-5 1.3934428770237704e-4 2.743620961955171e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 4/38 60/10654 5.81436596168192e-5 1.3934428770237704e-4 2.743620961955171e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5678895 Defective CFTR causes cystic fibrosis 4/38 61/10654 6.206527271282504e-5 1.4789267840713169e-4 2.911934599458859e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 4/38 63/10654 7.048288378815484e-5 1.65120014267756e-4 3.251132427839194e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 4/38 63/10654 7.048288378815484e-5 1.65120014267756e-4 3.251132427839194e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-9033241 Peroxisomal protein import 4/38 63/10654 7.048288378815484e-5 1.65120014267756e-4 3.251132427839194e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-450294 MAP kinase activation 4/38 64/10654 7.499008160486522e-5 1.7372702238460446e-4 3.4206002135552556e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-4608870 Asymmetric localization of PCP proteins 4/38 64/10654 7.499008160486522e-5 1.7372702238460446e-4 3.4206002135552556e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 4/38 65/10654 7.970376251293543e-5 1.8362690037510538e-4 3.615523975579508e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 4/38 66/10654 8.462965735360153e-5 1.9075982225109103e-4 3.755967723232387e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-6782135 Dual incision in TC-NER 4/38 66/10654 8.462965735360153e-5 1.9075982225109103e-4 3.755967723232387e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-69563 p53-Dependent G1 DNA Damage Response 4/38 66/10654 8.462965735360153e-5 1.9075982225109103e-4 3.755967723232387e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 4/38 66/10654 8.462965735360153e-5 1.9075982225109103e-4 3.755967723232387e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-162909 Host Interactions of HIV factors 5/38 129/10654 8.77198059630163e-5 1.9666214562676234e-4 3.872181587501569e-5 7316/7311/7314/6233/1025 5 Moloney_murine_leukemia_virus R-HSA-1169091 Activation of NF-kappaB in B cells 4/38 67/10654 8.977354743250739e-5 1.9807179512886552e-4 3.899936897652786e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 4/38 67/10654 8.977354743250739e-5 1.9807179512886552e-4 3.899936897652786e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5685942 HDR through Homologous Recombination (HRR) 4/38 67/10654 8.977354743250739e-5 1.9807179512886552e-4 3.899936897652786e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-3906995 Diseases associated with O-glycosylation of proteins 4/38 68/10654 9.514126347603446e-5 2.0556428429796048e-4 4.04746034967586e-5 4853/4851/4855/4854 4 Moloney_murine_leukemia_virus R-HSA-5658442 Regulation of RAS by GAPs 4/38 68/10654 9.514126347603446e-5 2.0556428429796048e-4 4.04746034967586e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-68867 Assembly of the pre-replicative complex 4/38 68/10654 9.514126347603446e-5 2.0556428429796048e-4 4.04746034967586e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-69615 G1/S DNA Damage Checkpoints 4/38 68/10654 9.514126347603446e-5 2.0556428429796048e-4 4.04746034967586e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-400253 Circadian Clock 4/38 70/10654 1.0657173726847836e-4 2.290743012420385e-4 4.5103610998053786e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-68949 Orc1 removal from chromatin 4/38 71/10654 1.1264639430925588e-4 2.4088998167671641e-4 4.743006076179195e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 4/38 72/10654 1.1896867387490857e-4 2.492961658584768e-4 4.908519736706093e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 4/38 72/10654 1.1896867387490857e-4 2.492961658584768e-4 4.908519736706093e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-448424 Interleukin-17 signaling 4/38 72/10654 1.1896867387490857e-4 2.492961658584768e-4 4.908519736706093e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 4/38 72/10654 1.1896867387490857e-4 2.492961658584768e-4 4.908519736706093e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-162599 Late Phase of HIV Life Cycle 5/38 139/10654 1.2487259737446537e-4 2.578921883644638e-4 5.077771221110231e-5 7316/7311/7314/6233/1025 5 Moloney_murine_leukemia_virus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 4/38 73/10654 1.2554463846039846e-4 2.578921883644638e-4 5.077771221110231e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5654738 Signaling by FGFR2 4/38 73/10654 1.2554463846039846e-4 2.578921883644638e-4 5.077771221110231e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 4/38 73/10654 1.2554463846039846e-4 2.578921883644638e-4 5.077771221110231e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-73887 Death Receptor Signalling 5/38 141/10654 1.3356568537996102e-4 2.73023974526685e-4 5.375708699503076e-5 7316/7311/6868/7314/6233 5 Moloney_murine_leukemia_virus R-HSA-1234174 Cellular response to hypoxia 4/38 75/10654 1.3948208843960415e-4 2.823496644626939e-4 5.5593269791973045e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 4/38 75/10654 1.3948208843960415e-4 2.823496644626939e-4 5.5593269791973045e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 4/38 76/10654 1.4685591165942394e-4 2.9300916345444876e-4 5.7692073076983466e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-204998 Cell death signalling via NRAGE, NRIF and NADE 4/38 76/10654 1.4685591165942394e-4 2.9300916345444876e-4 5.7692073076983466e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5693565 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 4/38 76/10654 1.4685591165942394e-4 2.9300916345444876e-4 5.7692073076983466e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5619084 ABC transporter disorders 4/38 77/10654 1.5450809361663078e-4 3.039145048968634e-4 5.983928153970805e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5693606 DNA Double Strand Break Response 4/38 77/10654 1.5450809361663078e-4 3.039145048968634e-4 5.983928153970805e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 4/38 77/10654 1.5450809361663078e-4 3.039145048968634e-4 5.983928153970805e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 4/38 79/10654 1.7067265038620154e-4 3.310255591211444e-4 6.51773156921602e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-6806834 Signaling by MET 4/38 79/10654 1.7067265038620154e-4 3.310255591211444e-4 6.51773156921602e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-8852135 Protein ubiquitination 4/38 79/10654 1.7067265038620154e-4 3.310255591211444e-4 6.51773156921602e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 4/38 80/10654 1.7919767891994882e-4 3.4595107458156786e-4 6.811607678243669e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-162587 HIV Life Cycle 5/38 152/10654 1.8999241456539804e-4 3.6510063075470496e-4 7.188653085666285e-5 7316/7311/7314/6233/1025 5 Moloney_murine_leukemia_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 4/38 82/10654 1.9716514700863558e-4 3.7542404704384036e-4 7.391916109912798e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-2871837 FCERI mediated NF-kB activation 4/38 82/10654 1.9716514700863558e-4 3.7542404704384036e-4 7.391916109912798e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 4/38 83/10654 2.066204575562832e-4 3.8811140000436975e-4 7.641723892551014e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-1236974 ER-Phagosome pathway 4/38 83/10654 2.066204575562832e-4 3.8811140000436975e-4 7.641723892551014e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-69202 Cyclin E associated events during G1/S transition 4/38 83/10654 2.066204575562832e-4 3.8811140000436975e-4 7.641723892551014e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 4/38 84/10654 2.1639879026010328e-4 4.0465603380476713e-4 7.967479650832221e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 4/38 85/10654 2.2650666500795286e-4 4.142687688961243e-4 8.156749709427666e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 4/38 85/10654 2.2650666500795286e-4 4.142687688961243e-4 8.156749709427666e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-69002 DNA Replication Pre-Initiation 4/38 85/10654 2.2650666500795286e-4 4.142687688961243e-4 8.156749709427666e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 4/38 85/10654 2.2650666500795286e-4 4.142687688961243e-4 8.156749709427666e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 4/38 85/10654 2.2650666500795286e-4 4.142687688961243e-4 8.156749709427666e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 4/38 86/10654 2.3695063383975316e-4 4.2960180135294374e-4 8.458649629062128e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-453276 Regulation of mitotic cell cycle 4/38 86/10654 2.3695063383975316e-4 4.2960180135294374e-4 8.458649629062128e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-190236 Signaling by FGFR 4/38 87/10654 2.47737280068855e-4 4.4721405103338756e-4 8.805426222543034e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 4/38 88/10654 2.5887321741153546e-4 4.6330528609703984e-4 9.122254781160951e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 4/38 88/10654 2.5887321741153546e-4 4.6330528609703984e-4 9.122254781160951e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5687128 MAPK6/MAPK4 signaling 4/38 89/10654 2.703650891245696e-4 4.818044536963484e-4 9.486494355248056e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-69052 Switching of origins to a post-replicative state 4/38 90/10654 2.82219567150839e-4 5.007896149017016e-4 9.86030290605395e-5 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-4086400 PCP/CE pathway 4/38 92/10654 3.070431682744922e-4 5.379705931532069e-4 1.0592378206727288e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 4/38 92/10654 3.070431682744922e-4 5.379705931532069e-4 1.0592378206727288e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 4/38 92/10654 3.070431682744922e-4 5.379705931532069e-4 1.0592378206727288e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-1257604 PIP3 activates AKT signaling 6/38 264/10654 3.100221305716657e-4 5.409172738426134e-4 1.0650396910191557e-4 7316/11060/7311/7314/1822/6233 6 Moloney_murine_leukemia_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 4/38 93/10654 3.2002577110989896e-4 5.537375375636012e-4 1.0902821640782757e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 4/38 93/10654 3.2002577110989896e-4 5.537375375636012e-4 1.0902821640782757e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 4/38 94/10654 3.3339793808113993e-4 5.74491488346427e-4 1.1311456794401444e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-1632852 Macroautophagy 4/38 95/10654 3.4716647202291987e-4 5.908915054430922e-4 1.1634365120424383e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 4/38 95/10654 3.4716647202291987e-4 5.908915054430922e-4 1.1634365120424383e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 4/38 95/10654 3.4716647202291987e-4 5.908915054430922e-4 1.1634365120424383e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 4/38 97/10654 3.7591996998401905e-4 6.372301930216908e-4 1.2546751244652755e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 4/38 98/10654 3.9091865510846436e-4 6.520523167209186e-4 1.2838591620404304e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 4/38 98/10654 3.9091865510846436e-4 6.520523167209186e-4 1.2838591620404304e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-202424 Downstream TCR signaling 4/38 98/10654 3.9091865510846436e-4 6.520523167209186e-4 1.2838591620404304e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5693607 Processing of DNA double-strand break ends 4/38 98/10654 3.9091865510846436e-4 6.520523167209186e-4 1.2838591620404304e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-1236975 Antigen processing-Cross presentation 4/38 99/10654 4.063411478371502e-4 6.697401527592555e-4 1.3186856472351867e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-166166 MyD88-independent TLR4 cascade 4/38 99/10654 4.063411478371502e-4 6.697401527592555e-4 1.3186856472351867e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 4/38 99/10654 4.063411478371502e-4 6.697401527592555e-4 1.3186856472351867e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-186712 Regulation of beta-cell development 3/38 42/10654 4.366079841210106e-4 7.167934227498481e-4 1.411331237523366e-4 9794/3516/4851 3 Moloney_murine_leukemia_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 4/38 101/10654 4.384852300726273e-4 7.170523174128846e-4 1.411840988469141e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 4/38 102/10654 4.5522070530662067e-4 7.386265918788359e-4 1.454319681094262e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5689603 UCH proteinases 4/38 102/10654 4.5522070530662067e-4 7.386265918788359e-4 1.454319681094262e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-382556 ABC-family proteins mediated transport 4/38 103/10654 4.7240775808242295e-4 7.605947301944801e-4 1.497573872401097e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-9020702 Interleukin-1 signaling 4/38 103/10654 4.7240775808242295e-4 7.605947301944801e-4 1.497573872401097e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5668914 Diseases of metabolism 4/38 104/10654 4.900533766080988e-4 7.859702232522201e-4 1.5475369787624175e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 4/38 106/10654 5.267483469995211e-4 8.41586439459005e-4 1.6570425918920205e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5688426 Deubiquitination 6/38 297/10654 5.806146443566799e-4 9.241080408272348e-4 1.819523594207354e-4 7316/7311/6314/7314/7706/6233 6 Moloney_murine_leukemia_virus R-HSA-2672351 Stimuli-sensing channels 4/38 109/10654 5.854056777984063e-4 9.281907514902487e-4 1.827562252082277e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 4/38 110/10654 6.05950332987702e-4 9.571260941510294e-4 1.8845345284306526e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5696398 Nucleotide Excision Repair 4/38 111/10654 6.270029011881982e-4 9.866423011150138e-4 1.9426504982196407e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 4/38 112/10654 6.485704848695851e-4 0.0010167439556038234 2.0019191855887475e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-913531 Interferon Signaling 5/38 199/10654 6.574446240931344e-4 0.0010267955365050076 2.021710257412359e-4 7316/7311/7314/7706/6233 5 Moloney_murine_leukemia_virus R-HSA-9006925 Intracellular signaling by second messengers 6/38 305/10654 6.678977300655845e-4 0.0010392289307363759 2.0461910033431105e-4 7316/11060/7311/7314/1822/6233 6 Moloney_murine_leukemia_virus R-HSA-5610787 Hedgehog 'off' state 4/38 113/10654 6.706601976343323e-4 0.001039647964362515 2.0470160600852247e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-202403 TCR signaling 4/38 119/10654 8.145627802792933e-4 0.001248796615354652 2.458819537994771e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-69239 Synthesis of DNA 4/38 119/10654 8.145627802792933e-4 0.001248796615354652 2.458819537994771e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-9612973 Autophagy 4/38 119/10654 8.145627802792933e-4 0.001248796615354652 2.458819537994771e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-2559580 Oxidative Stress Induced Senescence 4/38 125/10654 9.790644639503063e-4 0.0014954940713087096 2.944554778797914e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5689880 Ub-specific processing proteases 5/38 220/10654 0.0010333241132310872 0.0015726137051728592 3.0963995709575417e-4 7316/7311/6314/7314/6233 5 Moloney_murine_leukemia_virus R-HSA-69306 DNA Replication 4/38 127/10654 0.0010387441683033015 0.0015751138842999154 3.10132230153713e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 4/38 129/10654 0.001100942772286784 0.0016633809276941627 3.275115798564804e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs 4/38 130/10654 0.0011330046721916285 0.0017056424126494915 3.358326598173932e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-69206 G1/S Transition 4/38 131/10654 0.0011657179102498502 0.0017485768653747753 3.442862438450902e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 4/38 132/10654 0.0011990896904968673 0.0017921878169791887 3.528730271977199e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 4/38 134/10654 0.0012678376873183313 0.0018881725557562293 3.7177195342417236e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-162906 HIV Infection 5/38 233/10654 0.0013348144801205858 0.001980845687581083 3.9001884041732797e-4 7316/7311/7314/6233/1025 5 Moloney_murine_leukemia_virus R-HSA-5693538 Homology Directed Repair 4/38 138/10654 0.0014135529682384987 0.002090253857288844 4.1156077462711055e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-446652 Interleukin-1 family signaling 4/38 140/10654 0.0014906352995064551 0.0021964484801914905 4.324699771675786e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5621481 C-type lectin receptors (CLRs) 4/38 142/10654 0.0015706106701407806 0.002306143131861639 4.5406831827643035e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-3781865 Diseases of glycosylation 4/38 143/10654 0.0016117011618993688 0.002358173278989603 4.643128001039733e-4 4853/4851/4855/4854 4 Moloney_murine_leukemia_virus R-HSA-3858494 Beta-catenin independent WNT signaling 4/38 146/10654 0.0017394696999994822 0.0025273828045288644 4.976293291764519e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-8856828 Clathrin-mediated endocytosis 4/38 146/10654 0.0017394696999994822 0.0025273828045288644 4.976293291764519e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-453279 Mitotic G1-G1/S phases 4/38 149/10654 0.0018741336759771393 0.0027135893850085665 5.342924953443599e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-168898 Toll-like Receptor Cascades 4/38 155/10654 0.0021649153150114526 0.003123770541037286 6.150551614310446e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5633007 Regulation of TP53 Activity 4/38 160/10654 0.0024299902360759786 0.0034941583739437347 6.879827165659759e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-69242 S Phase 4/38 161/10654 0.0024855719382631957 0.0035617989630781876 7.013008181751828e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-9609507 Protein localization 4/38 163/10654 0.0025993577711362487 0.003712096543026766 7.308936775365084e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-5693532 DNA Double-Strand Break Repair 4/38 166/10654 0.0027766964205405823 0.003951817089984378 7.780934823142283e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-69481 G2/M Checkpoints 4/38 168/10654 0.0028994424971223775 0.0041124745622450045 8.09726153868763e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 4/38 171/10654 0.003090479013579223 0.004368575419195037 8.60151161674146e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-8940973 RUNX2 regulates osteoblast differentiation 2/38 24/10654 0.0032539183568696304 0.00458406741491431 9.025804830577212e-4 23462/23493 2 Moloney_murine_leukemia_virus R-HSA-5619115 Disorders of transmembrane transporters 4/38 176/10654 0.0034277721352449033 0.004812730573727692 9.476031421198032e-4 7316/7311/7314/6233 4 Moloney_murine_leukemia_virus R-HSA-109581 Apoptosis 4/38 178/10654 0.003569461048844149 0.004994849856939631 9.834615394201471e-4 7316/7311/7314/6233 4 Mumps_virus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 253/1098 309/10654 1.3734281838482176e-202 1.7016775197879416e-199 9.773025813488371e-200 8454/9354/57154/197131/23352/26224/8945/10293/51088/140460/79754/6737/8065/64410/127544/114088/11065/285231/221687/9666/84937/57531/142678/55070/84708/246184/146330/55819/51320/93611/7319/54850/142686/8916/79791/26046/151636/7321/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/8697/7320/26235/10477/9817/10193/148581/9039/223082/92912/154881/140739/25897/6500/6478/150726/390594/10533/81559/144699/140462/26259/57674/51130/53339/154214/7336/200845/79876/26263/64750/51619/6477/9690/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/9604/9978/22888/23304/7317/80196/114907/140456/64718/54926/4008/7335/84861/11059/55236/84085/55958/54620/4734/84078/7337/26272/84676/27252/51444/7704/8651/3093/26118/222235/51433/25831/7322/5715/64219/10489/23327/9867/26249/140458/55905/55336/26270/143279/51465/63893/89122/6502/23291/118424/10616/27246/89910/55521/25898/9903/201456/55294/26190/55008/7328/79654/10422/84727/135892/7428/22954/8453/401036/83737/51529/9040/90933/140461/7324/63891/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/6233/90135/56658/9870/51434/6468/26267/142685/4012/25847/90025/7327/10425/25793/51343/7311/26091/23295/6047/84541/7318/23194/51666/90293/131405/55175/55284/868/54461/9320/136371/80204/26232/29882/57520/26234/127247/27338/7334/92591/5930/11275/55182/84961/4591/23014/29116/26268/92369/115290/90678/51725/140459/997/23608/51676/55585/64320/51132/84261/7325/57542/9820/55658/7314/996/10324/283807/140691/899 253 Mumps_virus R-HSA-983169 Class I MHC mediated antigen processing & presentation 269/1098 371/10654 1.412823184280621e-190 8.752439626618447e-188 5.0266761714405263e-188 8454/9354/23643/57154/1147/197131/23352/26224/8945/10293/51088/140460/79754/6737/8065/64410/127544/114088/11065/285231/221687/9666/84937/57531/142678/55070/84708/246184/146330/55819/51320/93611/7319/54850/142686/8916/79791/26046/151636/7321/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/8697/7320/26235/10477/9817/10193/6890/148581/9039/223082/92912/154881/140739/25897/6500/6478/150726/390594/10533/81559/144699/140462/26259/57674/51130/10333/7099/53339/8517/154214/7336/200845/4615/79876/26263/64750/51619/6477/9690/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/9604/9978/22888/23304/7317/80196/114907/140456/64718/54926/4008/7335/7096/84861/11059/55236/84085/55958/54620/4734/84078/7337/26272/84676/27252/51444/7704/8651/3093/26118/222235/51433/25831/7322/5715/64219/10489/23327/9867/26249/140458/55905/55336/26270/143279/51465/63893/89122/6502/23291/118424/10616/929/27246/89910/55521/114609/25898/9903/201456/55294/26190/55008/7328/79654/10422/84727/135892/7428/22954/8453/401036/83737/51529/9040/695/90933/140461/7324/63891/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/6233/90135/56658/9870/51434/6468/26267/948/142685/4012/25847/90025/7327/10425/25793/51343/7311/26091/23295/6047/84541/7318/23194/51666/90293/131405/55175/55284/868/54461/9320/136371/80204/26232/29882/57520/26234/127247/27338/7334/92591/5930/11275/55182/7097/84961/4591/3551/23014/29116/26268/92369/1536/115290/90678/51725/140459/997/23608/51676/55585/64320/51132/84261/7325/57542/9820/55658/7314/996/4360/10324/283807/140691/899 269 Mumps_virus R-HSA-8951664 Neddylation 157/1098 234/10654 2.87070628232476e-100 1.185601694600126e-97 6.809113848601888e-98 8454/9318/51397/26224/54165/8945/56995/23412/51088/9655/140460/79754/8065/64410/149951/29099/285231/23038/146330/93611/54850/142686/55884/79791/7321/51665/9616/122769/9021/4738/26235/9817/9039/154881/140739/6500/150726/390594/144699/140462/28952/26259/51130/53339/28991/200845/26263/140825/8452/8450/7323/9306/10517/89890/142689/7316/9978/114907/140456/4008/84861/64708/84085/55958/54620/84078/55527/26272/27252/7704/26118/222235/10980/7322/5715/122416/10489/26249/140458/55336/26270/6502/7347/23291/170622/90864/55832/10920/9903/201456/55294/26190/84727/10987/7428/8453/123879/401036/9040/140461/79176/80176/8139/23142/126433/10116/6233/90135/6468/2873/26267/142685/25793/7311/1154/84541/23194/83987/51666/90293/55175/8533/54461/136371/80204/26232/8835/26234/127247/8883/92591/11275/51122/84961/54939/23014/26268/92369/115290/54951/51725/140459/55208/84259/51676/84261/150684/50813/57542/9820/7314/51138/10324/8451/56929/283807/899 157 Mumps_virus R-HSA-168898 Toll-like Receptor Cascades 106/1098 155/10654 1.2334360492627896e-68 3.820568162591491e-66 2.1942178139517e-66 54106/8454/23643/1147/3665/3725/11035/4064/8945/1326/10695/351/81793/4790/6885/11213/7184/7321/8737/10392/653509/8767/5336/3684/1849/29110/5594/6271/1785/4214/6500/330/51295/23118/6280/10333/841/7099/8517/4615/7098/7100/338/5528/7323/7316/7335/7096/5970/4792/59307/6279/177/8651/26052/3146/7322/5519/64127/1432/329/23291/2244/929/114609/3656/10454/3661/695/3654/7189/6285/6233/51311/10010/948/2266/51135/1385/81622/7311/1759/5518/2243/7187/1386/8772/9641/6197/5599/353376/5600/7334/7097/3929/3551/6416/5781/9450/51284/7314/5595/5515/148022/257397/5516 106 Mumps_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 90/1098 129/10654 1.763593035433058e-59 4.3701835418031176e-57 2.5098713514794682e-57 8454/23643/1147/3665/3725/11035/4064/8945/1326/351/4790/6885/11213/7321/8737/10392/653509/8767/5336/3684/1849/29110/5594/1785/4214/6500/330/51295/23118/10333/841/7099/8517/4615/5528/7323/7316/7335/7096/5970/4792/59307/177/8651/26052/3146/7322/5519/64127/1432/329/23291/929/114609/3656/10454/3661/695/3654/7189/6285/6233/10010/948/51135/1385/7311/1759/5518/7187/1386/8772/9641/6197/5599/353376/5600/7334/7097/3929/3551/6416/5781/9450/7314/5595/5515/148022/257397/5516 90 Mumps_virus R-HSA-449147 Signaling by Interleukins 170/1098 461/10654 2.4659268352742773e-55 5.092138914841382e-53 2.9245027028866875e-53 5295/729230/8454/3605/7124/1147/2308/834/3725/5777/8945/1326/596/9655/351/3592/5290/3566/1437/3667/4790/6885/2309/90865/5291/3561/11213/3587/7184/10392/8767/3593/6775/207/3684/9021/1849/7422/29110/3553/1230/1439/5594/3595/54472/2919/6500/5743/941/23118/4318/3383/4478/8517/6778/3576/4615/3313/3597/6776/5528/3688/1436/7316/3565/9978/2920/3560/6352/6774/1435/7335/1441/5970/4792/6850/1026/6348/59307/3718/1440/3627/7133/3606/177/6772/8651/4609/3146/149233/5715/5519/64127/8503/1432/867/3558/4067/3717/23291/4088/598/836/3320/4843/2534/3656/3458/10454/998/7157/942/3654/3563/7189/6285/6233/2885/7525/1398/7006/948/6844/3716/7409/51135/8660/1385/7311/3594/1154/6347/3932/3575/5293/5518/2185/1386/5296/3687/51561/3570/6197/8835/5599/5600/7431/6777/7334/5008/3312/1399/3559/3929/3551/6773/7297/6416/5781/3569/3162/3586/3554/7314/3572/3596/5595/5515/257397/5516 170 Mumps_virus R-HSA-166166 MyD88-independent TLR4 cascade 68/1098 99/10654 2.3173185633920693e-44 3.5889471250534676e-42 2.0611938800697886e-42 8454/23643/1147/3665/3725/11035/8945/1326/351/4790/6885/7321/8737/10392/8767/1849/29110/5594/6500/330/23118/841/7099/8517/5528/7323/7316/7335/5970/4792/177/3146/7322/5519/64127/1432/329/23291/929/3656/10454/3661/3654/7189/6285/6233/10010/1385/7311/5518/7187/1386/8772/9641/6197/5599/353376/5600/7334/3551/6416/5781/7314/5595/5515/148022/257397/5516 68 Mumps_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 68/1098 99/10654 2.3173185633920693e-44 3.5889471250534676e-42 2.0611938800697886e-42 8454/23643/1147/3665/3725/11035/8945/1326/351/4790/6885/7321/8737/10392/8767/1849/29110/5594/6500/330/23118/841/7099/8517/5528/7323/7316/7335/5970/4792/177/3146/7322/5519/64127/1432/329/23291/929/3656/10454/3661/3654/7189/6285/6233/10010/1385/7311/5518/7187/1386/8772/9641/6197/5599/353376/5600/7334/3551/6416/5781/7314/5595/5515/148022/257397/5516 68 Mumps_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 64/1098 94/10654 1.9855698178914467e-41 2.733467782630558e-39 1.5698774232685595e-39 8454/1147/3665/3725/11035/8945/1326/351/4790/6885/7321/8737/10392/8767/1849/29110/5594/6500/330/23118/841/8517/7098/5528/7323/7316/7335/5970/4792/177/3146/7322/5519/64127/1432/329/23291/3656/10454/3661/3654/7189/6285/6233/10010/1385/7311/5518/7187/1386/8772/9641/6197/5599/5600/7334/3551/6416/7314/5595/5515/148022/257397/5516 64 Mumps_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 63/1098 95/10654 1.0148037399772716e-39 9.829347180414087e-38 5.64516264726216e-38 8454/23643/1147/3725/8945/1326/351/4790/6885/11213/10392/8767/1849/5594/4214/6500/51295/23118/10333/7099/8517/4615/5528/7316/7335/7096/5970/4792/59307/177/8651/3146/5519/64127/1432/23291/929/114609/3656/10454/695/3654/7189/6285/6233/948/51135/1385/7311/5518/1386/6197/5599/5600/7334/7097/3551/6416/7314/5595/5515/257397/5516 63 Mumps_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 63/1098 95/10654 1.0148037399772716e-39 9.829347180414087e-38 5.64516264726216e-38 8454/23643/1147/3725/8945/1326/351/4790/6885/11213/10392/8767/1849/5594/4214/6500/51295/23118/10333/7099/8517/4615/5528/7316/7335/7096/5970/4792/59307/177/8651/3146/5519/64127/1432/23291/929/114609/3656/10454/695/3654/7189/6285/6233/948/51135/1385/7311/5518/1386/6197/5599/5600/7334/7097/3551/6416/7314/5595/5515/257397/5516 63 Mumps_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 64/1098 98/10654 1.0313277913267405e-39 9.829347180414087e-38 5.64516264726216e-38 8454/23643/1147/3725/8945/1326/351/4790/6885/11213/10392/653509/8767/1849/5594/4214/6500/51295/23118/10333/7099/8517/4615/5528/7316/7335/7096/5970/4792/59307/177/8651/3146/5519/64127/1432/23291/929/114609/3656/10454/695/3654/7189/6285/6233/948/51135/1385/7311/5518/1386/6197/5599/5600/7334/7097/3551/6416/7314/5595/5515/257397/5516 64 Mumps_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 64/1098 98/10654 1.0313277913267405e-39 9.829347180414087e-38 5.64516264726216e-38 8454/23643/1147/3725/8945/1326/351/4790/6885/11213/10392/653509/8767/1849/5594/4214/6500/51295/23118/10333/7099/8517/4615/5528/7316/7335/7096/5970/4792/59307/177/8651/3146/5519/64127/1432/23291/929/114609/3656/10454/695/3654/7189/6285/6233/948/51135/1385/7311/5518/1386/6197/5599/5600/7334/7097/3551/6416/7314/5595/5515/257397/5516 64 Mumps_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 60/1098 93/10654 7.853268041577497e-37 6.486799402343012e-35 3.725480137618518e-35 54106/8454/23643/1147/3665/3725/8945/1326/351/4790/6885/10392/8767/1849/5594/4214/6500/51295/23118/7099/8517/4615/5528/7316/7335/5970/4792/177/3146/5519/64127/1432/23291/929/3656/10454/3654/7189/6285/6233/51311/51135/1385/7311/5518/1386/6197/5599/353376/5600/7334/3551/6416/51284/7314/5595/5515/148022/257397/5516 60 Mumps_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 60/1098 93/10654 7.853268041577497e-37 6.486799402343012e-35 3.725480137618518e-35 54106/8454/23643/1147/3665/3725/8945/1326/351/4790/6885/10392/8767/1849/5594/4214/6500/51295/23118/7099/8517/4615/5528/7316/7335/5970/4792/177/3146/5519/64127/1432/23291/929/3656/10454/3654/7189/6285/6233/51311/51135/1385/7311/5518/1386/6197/5599/353376/5600/7334/3551/6416/51284/7314/5595/5515/148022/257397/5516 60 Mumps_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 59/1098 92/10654 5.156159306444425e-36 3.992800862927901e-34 2.2931340073397577e-34 54106/8454/23643/1147/3725/8945/1326/351/4790/6885/10392/8767/1849/5594/4214/6500/51295/23118/7099/8517/4615/5528/7316/7335/5970/4792/177/3146/5519/64127/1432/23291/929/3656/10454/3654/7189/6285/6233/51311/51135/1385/7311/5518/1386/6197/5599/353376/5600/7334/3551/6416/51284/7314/5595/5515/148022/257397/5516 59 Mumps_virus R-HSA-1257604 PIP3 activates AKT signaling 103/1098 264/10654 7.888980854221291e-36 5.7496748696354e-34 3.302136877680244e-34 5295/1147/2308/5170/3725/23396/3643/5290/3667/2309/90865/23035/5291/5468/2065/5525/1822/23186/842/3815/572/23239/5526/10273/207/6045/5594/4303/84335/1027/7249/941/2064/57761/6199/4615/5528/2100/7316/4233/1026/55615/4734/6714/2099/64223/10014/5715/5519/8503/2932/2261/3164/10000/3084/2534/23512/5728/6009/5529/6615/3630/7157/23028/942/3654/7189/5371/208/6233/5527/2885/79109/2475/7409/51135/8660/1385/7311/3932/2931/5293/5518/5155/1386/1956/4254/118788/5296/4343/117145/648/5781/57521/23608/940/7314/5879/253260/5595/4193/5515/5516 103 Mumps_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 60/1098 97/10654 2.7444192993042457e-35 1.889075284354422e-33 1.0849283311869418e-33 54106/8454/23643/1147/3665/3725/8945/1326/351/4790/6885/10392/8767/1849/5594/4214/6500/51295/23118/7099/8517/4615/5528/7316/7335/5970/4792/177/3146/5519/64127/1432/23291/929/3656/10454/3654/7189/6285/6233/51311/51135/1385/7311/5518/1386/6197/5599/353376/5600/7334/3551/6416/51284/7314/5595/5515/148022/257397/5516 60 Mumps_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 51/1098 78/10654 6.894682498967066e-32 4.49605874537905e-30 2.5821636395023472e-30 1147/3443/3665/3441/351/4790/7321/8737/29110/57506/4214/54476/3449/841/7706/8517/3444/7323/7316/5970/4792/177/3093/3146/23586/7322/3451/3448/64135/3440/83737/3661/9246/7189/6285/51191/6233/10010/7311/7318/7187/8772/5300/3452/9641/1540/3551/3456/3446/7314/3445 51 Mumps_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 138/1098 473/10654 7.403014101461489e-32 4.586167235855393e-30 2.6339144908357722e-30 5295/54106/5170/5777/1173/3643/5590/4893/8065/857/5290/2670/3667/85440/5335/558/5291/1499/2065/5747/4690/526/3815/5430/10273/207/10019/1849/7422/5594/10193/2322/1785/3315/9101/10817/23118/51741/23385/4318/2064/57761/5921/6778/348/6776/5528/9306/3688/7316/5753/5140/9047/6774/11059/4233/55615/4734/10413/6772/6714/2099/8651/26052/64223/5519/3673/8503/1432/2261/867/5437/4067/3717/4914/529/10000/9146/3320/3084/2534/4846/8471/1445/5603/3630/998/83737/3914/6285/208/1742/6233/2885/7525/1398/79109/7410/7006/2475/7409/8660/1385/163/7311/3932/3479/1759/5518/5155/2185/387/1956/60/4254/5296/117145/6197/3845/5600/6777/3265/1399/6300/801/1020/5781/1536/3480/11140/53916/7314/5879/253260/5595/5515/6387/5516 138 Mumps_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 53/1098 85/10654 1.5114050276870963e-31 8.141873170888314e-30 4.676017385430102e-30 8454/1147/3725/8945/1326/351/81793/4790/6885/10392/8767/1849/5594/4214/6500/51295/23118/8517/4615/7100/5528/7316/7335/5970/4792/177/3146/5519/64127/1432/23291/3656/10454/3654/7189/6285/6233/51135/1385/7311/5518/1386/6197/5599/5600/7334/3551/6416/7314/5595/5515/257397/5516 53 Mumps_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 53/1098 85/10654 1.5114050276870963e-31 8.141873170888314e-30 4.676017385430102e-30 8454/1147/3725/8945/1326/351/81793/4790/6885/10392/8767/1849/5594/4214/6500/51295/23118/8517/4615/7100/5528/7316/7335/5970/4792/177/3146/5519/64127/1432/23291/3656/10454/3654/7189/6285/6233/51135/1385/7311/5518/1386/6197/5599/5600/7334/3551/6416/7314/5595/5515/257397/5516 53 Mumps_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 53/1098 85/10654 1.5114050276870963e-31 8.141873170888314e-30 4.676017385430102e-30 8454/1147/3725/8945/1326/351/81793/4790/6885/10392/8767/1849/5594/4214/6500/51295/23118/8517/4615/7100/5528/7316/7335/5970/4792/177/3146/5519/64127/1432/23291/3656/10454/3654/7189/6285/6233/51135/1385/7311/5518/1386/6197/5599/5600/7334/3551/6416/7314/5595/5515/257397/5516 53 Mumps_virus R-HSA-9006925 Intracellular signaling by second messengers 105/1098 305/10654 5.643757071473924e-31 2.9135895881484136e-29 1.6733244650510412e-29 5295/1147/2308/5170/3725/23396/3643/5290/3667/5335/2309/90865/23035/5291/5468/2065/5525/1822/23186/842/3815/572/23239/5526/10273/207/6045/5594/4303/84335/1027/7249/941/2064/57761/6199/4615/5528/2100/7316/4233/1026/55615/4734/6714/2099/64223/10014/5715/5519/8503/2932/2261/3164/10000/3084/2534/23512/5728/6009/5529/6615/3630/7157/23028/942/3654/7189/5371/208/6233/5527/2885/79109/2475/7409/51135/8660/1385/7311/3932/2931/5293/5518/5155/1386/1956/4254/118788/5296/4343/117145/648/801/5781/57521/23608/940/7314/5879/253260/5595/4193/5515/5516 105 Mumps_virus R-HSA-2219528 PI3K/AKT Signaling in Cancer 56/1098 101/10654 1.7097879731495168e-29 8.473709194929005e-28 4.866596504627678e-28 5295/1147/2308/5170/5290/3667/2309/5291/2065/842/3815/572/207/4303/84335/1027/7249/941/2064/6199/2100/4233/1026/55615/6714/2099/64223/8503/2932/2261/3164/10000/3084/2534/5728/942/208/2885/79109/2475/7409/8660/1385/3932/2931/5293/5155/1956/4254/118788/5296/5781/940/5879/253260/4193 56 Mumps_virus R-HSA-9009391 Extra-nuclear estrogen signaling 48/1098 77/10654 1.141410018427195e-28 5.4392577416588256e-27 3.123858997800745e-27 5295/2788/5170/596/5590/4893/857/5290/54331/2309/5747/59345/207/5594/1027/3315/10681/51764/94235/4318/2100/55970/2792/6714/2099/8503/2793/10000/3320/2785/4846/2783/2784/2782/2786/208/7514/1385/1956/5296/3845/3265/801/3480/2791/5595/2790/2787 48 Mumps_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 40/1098 55/10654 4.48816975541427e-28 2.0595712322067703e-26 1.1828470778401744e-26 1147/834/596/351/4790/6885/842/10392/8767/10910/58484/7295/330/23118/841/8517/7316/7335/5970/64127/1432/329/598/3656/5603/10454/83737/3654/7189/6233/3326/7311/114548/5600/7334/1540/3551/6300/7314/257397 40 Mumps_virus R-HSA-199418 Negative regulation of the PI3K/AKT network 57/1098 110/10654 6.1733715939324095e-28 2.731716930315091e-26 1.568871878758763e-26 5295/23396/3643/5290/3667/90865/23035/5291/2065/5525/3815/23239/5526/207/5594/941/2064/57761/4615/5528/2100/4233/6714/2099/5519/8503/2261/10000/3084/2534/5728/5529/3630/942/3654/7189/208/5527/2885/7409/51135/8660/3932/5293/5518/5155/1956/4254/118788/5296/117145/5781/940/5879/5595/5515/5516 57 Mumps_virus R-HSA-388841 Costimulation by the CD28 family 45/1098 70/10654 8.568127156053178e-28 3.660658464258582e-26 2.1023789319390016e-26 5295/5170/5777/1326/5290/5525/5526/207/5133/941/57761/5528/9020/55615/3113/6714/64223/5519/8503/29126/4067/10000/2534/5529/1445/998/942/208/5527/2885/7525/79109/2475/7409/3932/5518/5296/117145/5781/1493/940/5879/253260/5515/5516 45 Mumps_virus R-HSA-5663202 Diseases of signal transduction 111/1098 377/10654 5.075418118641411e-26 2.0961476829989027e-24 1.2038535607724893e-24 5295/8454/1147/2308/5170/4893/5290/3667/5335/142678/2309/5291/1499/2065/10018/5525/892/842/55750/3815/572/5430/5526/207/5594/4303/84335/1027/7249/6500/941/10533/23385/2064/6199/6776/5528/2100/7316/9978/6774/4233/1026/55615/6772/6714/2099/4609/64223/10014/5715/5519/8503/2932/2261/867/5437/3717/4088/2244/3164/10000/3320/3084/2534/55294/5728/5529/1445/5894/4087/942/208/6233/5527/2885/79109/2475/2266/7409/8660/1385/7311/3932/2931/5293/5518/5155/2243/1956/60/4254/118788/5296/3845/6777/3265/369/801/5781/7750/11140/5245/940/7314/5879/253260/5595/4193/5515/5516 111 Mumps_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 54/1098 108/10654 1.5725574119754138e-25 6.229952905621661e-24 3.577968789941161e-24 5295/3605/7124/2308/596/9655/3592/3566/2309/3561/7184/3593/207/3684/9021/7422/3553/5743/4318/3383/6778/3576/3597/3688/3565/6774/1026/3718/7133/3606/6772/8651/4609/149233/3717/598/3320/4843/7157/948/3716/6347/3687/51561/3570/7431/5008/3312/3929/7297/3569/3162/3586/3596 54 Mumps_virus R-HSA-392451 G beta:gamma signalling through PI3Kgamma 25/1098 25/10654 1.6593094906014108e-25 6.229952905621661e-24 3.577968789941161e-24 2788/5170/54331/59345/207/10681/51764/94235/55970/2792/146850/2793/23533/10000/5294/2785/2783/2784/2782/2786/208/387/2791/2790/2787 25 Mumps_virus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 25/1098 25/10654 1.6593094906014108e-25 6.229952905621661e-24 3.577968789941161e-24 1147/2308/5170/2309/842/572/207/4303/84335/1027/7249/6199/1026/55615/64223/2932/3164/10000/208/79109/2475/1385/2931/253260/4193 25 Mumps_virus R-HSA-450294 MAP kinase activation 41/1098 64/10654 2.433585741241027e-25 8.868272745287154e-24 5.093201117891438e-24 8454/1147/3725/8945/1326/4790/6885/10392/8767/1849/5594/6500/23118/8517/5528/7316/7335/5519/64127/1432/23291/3656/10454/3654/7189/6233/1385/7311/5518/1386/6197/5599/5600/7334/3551/6416/7314/5595/5515/257397/5516 41 Mumps_virus R-HSA-389356 CD28 co-stimulation 29/1098 33/10654 4.6598203406486e-25 1.6495764005896043e-23 9.473800151213396e-24 5295/5170/1326/5290/207/941/57761/9020/55615/6714/64223/8503/4067/10000/2534/998/942/208/2885/7525/79109/2475/7409/3932/5296/117145/940/5879/253260 29 Mumps_virus R-HSA-168638 NOD1/2 Signaling Pathway 30/1098 36/10654 1.8183762906433306e-24 6.258245066964129e-23 3.5942174633768765e-23 1147/834/6885/842/10392/8767/330/23118/841/8517/7316/7335/64127/1432/329/3656/5603/10454/83737/3654/7189/6233/7311/5600/7334/1540/3551/6300/7314/257397 30 Mumps_virus R-HSA-448424 Interleukin-17 signaling 42/1098 72/10654 1.3268449076793224e-23 4.443137407066704e-22 2.5517700073718976e-22 8454/3605/1147/3725/8945/1326/4790/6885/10392/8767/1849/5594/6500/23118/8517/5528/7316/7335/5519/64127/1432/23291/3656/10454/3654/7189/6233/1385/7311/5518/1386/6197/5599/5600/7334/3551/6416/7314/5595/5515/257397/5516 42 Mumps_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 34/1098 48/10654 2.0161413430685873e-23 6.573681905426263e-22 3.775378249070264e-22 5295/5777/5290/1437/5291/3561/1439/6776/7316/3560/6850/3718/8503/867/3558/4067/3717/2534/3563/6233/2885/7525/1398/7006/3716/7409/7311/5293/5296/6777/1399/3559/5781/7314 34 Mumps_virus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 50/1098 103/10654 5.56404778543723e-23 1.7676551810658275e-21 1.0151946836587228e-21 5295/23396/3643/5290/3667/90865/5291/2065/5525/3815/5526/207/5594/941/2064/4615/5528/2100/4233/6714/2099/5519/8503/2261/3084/2534/5529/3630/942/3654/7189/5527/2885/7409/51135/8660/3932/5293/5518/5155/1956/4254/118788/5296/5781/940/5879/5595/5515/5516 50 Mumps_virus R-HSA-389357 CD28 dependent PI3K/Akt signaling 22/1098 22/10654 1.6048140978602118e-22 4.970911668122006e-21 2.85487981619343e-21 5295/5170/1326/5290/207/941/57761/9020/55615/64223/8503/10000/2534/942/208/79109/2475/3932/5296/117145/940/253260 22 Mumps_virus R-HSA-397795 G-protein beta:gamma signalling 27/1098 32/10654 2.04084417042749e-22 6.1673315296577075e-21 3.5420042598433466e-21 2788/5170/54331/59345/207/10681/51764/94235/55970/2792/146850/2793/23533/10000/5294/2785/2783/2784/2782/998/695/2786/208/387/2791/2790/2787 27 Mumps_virus R-HSA-5260271 Diseases of Immune System 23/1098 24/10654 3.5201908001067935e-22 1.0143061398447248e-20 5.8253341025023076e-21 23643/1147/81793/4790/10333/7099/8517/4615/7098/7100/7096/5970/4792/929/114609/695/948/51135/81622/7187/7097/3551/148022 23 Mumps_virus R-HSA-5602358 Diseases associated with the TLR signaling cascade 23/1098 24/10654 3.5201908001067935e-22 1.0143061398447248e-20 5.8253341025023076e-21 23643/1147/81793/4790/10333/7099/8517/4615/7098/7100/7096/5970/4792/929/114609/695/948/51135/81622/7187/7097/3551/148022 23 Mumps_virus R-HSA-389513 CTLA4 inhibitory signaling 21/1098 21/10654 1.5844000280916998e-21 4.4615264427400365e-20 2.562331145909065e-20 5525/5526/207/941/5528/6714/5519/4067/10000/2534/5529/942/208/5527/7525/3932/5518/5781/1493/5515/5516 21 Mumps_virus R-HSA-4420097 VEGFA-VEGFR2 Pathway 47/1098 99/10654 3.706311712744207e-21 1.0204711582422384e-19 5.860740860386161e-20 5295/5170/5590/4893/857/5290/5335/558/5291/1499/5747/4690/207/7422/3315/57761/5921/9047/55615/6714/64223/1432/10000/3320/2534/4846/5603/998/208/1398/79109/7410/2475/7409/2185/387/60/5296/117145/3845/5600/3265/6300/801/1536/5879/253260 47 Mumps_virus R-HSA-1433557 Signaling by SCF-KIT 30/1098 43/10654 1.6683114426741774e-20 4.493560603202839e-19 2.5807289136103984e-19 5295/5777/4893/5290/3815/10019/4318/6776/9306/6774/6772/6714/8651/8503/867/4067/3717/2534/2885/7525/7006/7409/3932/4254/5296/3845/6777/3265/5781/5879 30 Mumps_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 26/1098 33/10654 3.5003058312215785e-20 9.22740196783731e-19 5.299455189038718e-19 1147/351/4790/6885/10392/8767/23118/8517/7316/7335/5970/4792/177/3146/64127/3656/10454/3654/7189/6285/6233/7311/7334/3551/7314/257397 26 Mumps_virus R-HSA-194138 Signaling by VEGF 47/1098 107/10654 2.0830353526304565e-19 5.376835003977366e-18 3.088008549074976e-18 5295/5170/5590/4893/857/5290/5335/558/5291/1499/5747/4690/207/7422/3315/57761/5921/9047/55615/6714/64223/1432/10000/3320/2534/4846/5603/998/208/1398/79109/7410/2475/7409/2185/387/60/5296/117145/3845/5600/3265/6300/801/1536/5879/253260 47 Mumps_virus R-HSA-937041 IKK complex recruitment mediated by RIP1 22/1098 25/10654 2.7196615126401513e-19 6.87685839624724e-18 3.9494977068630346e-18 23643/1147/11035/7321/8737/330/7099/8517/7323/7316/7335/7322/329/929/7189/6233/7311/353376/7334/3551/7314/148022 22 Mumps_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 53/1098 134/10654 3.266766338762794e-19 8.095046987454203e-18 4.64912430527084e-18 5295/8454/1147/5170/3725/8945/4893/5290/5335/4790/6885/5291/7321/5336/5594/4214/6500/23118/8517/7316/7335/5970/4792/6850/8915/7322/5715/4067/23291/2534/10454/695/7189/6233/2885/7410/7006/7409/3702/7311/5296/3845/5599/7334/3265/3551/801/6416/997/7314/5879/5595/257397 53 Mumps_virus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 24/1098 30/10654 5.287891384301302e-19 1.2846465539508455e-17 7.377945460862087e-18 11065/7319/7321/65264/7320/10477/92912/7326/7316/7317/54926/55236/3093/7322/7347/7328/7324/6233/7327/7311/55284/27338/997/7314 24 Mumps_virus R-HSA-8964315 G beta:gamma signalling through BTK 18/1098 18/10654 1.5170970340086094e-18 3.6147754329551286e-17 2.076027520222308e-17 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/695/2786/2791/2790/2787 18 Mumps_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 19/1098 20/10654 2.784020415062951e-18 6.508304328798106e-17 3.737830785665452e-17 1147/11035/7321/8737/330/8517/7098/7323/7316/7335/7322/329/7189/6233/7311/7334/3551/7314/148022 19 Mumps_virus R-HSA-9607240 FLT3 Signaling 77/1098 267/10654 1.0130326775153222e-17 2.3243471989657117e-16 1.3349124561410487e-16 5295/54106/5170/2674/4893/5290/1437/3667/5291/2065/3561/5525/5747/3815/5526/1849/7010/1439/5594/2322/10817/2064/57761/5921/8452/6776/5528/7316/9978/3560/5140/4233/84078/3718/6714/5715/5519/2261/3558/3717/2244/3084/2534/5529/1445/5894/3563/208/1742/6233/5527/2885/6709/3716/2266/8660/7311/5518/5155/2243/1956/60/4254/5296/117145/3845/6777/3265/3559/369/801/5781/5245/7314/5595/5515/5516 77 Mumps_virus R-HSA-6783783 Interleukin-10 signaling 29/1098 47/10654 1.242638321437423e-17 2.799325236838122e-16 1.6077004885965513e-16 729230/7124/3592/1437/3587/3593/3553/1230/2919/5743/941/3383/3576/2920/6352/6774/1435/6348/1440/3627/7133/3606/942/3716/6347/7297/3569/3586/3554 29 Mumps_virus R-HSA-9006335 Signaling by Erythropoietin 21/1098 25/10654 1.3345983280176611e-17 2.952798800739075e-16 1.6958429882329682e-16 5295/4893/5290/5335/5291/5336/6776/4067/23533/3717/5294/2057/2885/2056/7409/8660/5293/3845/6777/3265/1399 21 Mumps_virus R-HSA-446652 Interleukin-1 family signaling 52/1098 140/10654 1.804421558309297e-17 3.922242650430209e-16 2.252611215913361e-16 8454/1147/834/5777/8945/1326/351/4790/6885/90865/11213/10392/8767/29110/3553/54472/6500/23118/8517/4615/7316/3565/9978/6774/7335/5970/4792/59307/3606/177/3146/5715/64127/23291/4088/3656/10454/3654/7189/6285/6233/51135/7311/5599/7334/3551/6416/5781/3554/7314/3596/257397 52 Mumps_virus R-HSA-392851 Prostacyclin signalling through prostacyclin receptor 18/1098 19/10654 2.6051962267719608e-17 5.565238146500793e-16 3.196211704714784e-16 2788/54331/59345/10681/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 18 Mumps_virus R-HSA-5683057 MAPK family signaling cascades 80/1098 294/10654 9.733122631781451e-17 2.043955752674105e-15 1.1738788401577632e-15 2308/3725/2674/4893/1437/3667/2309/2065/3561/5525/5747/3815/5526/1849/7010/1439/5594/2322/3315/10817/2064/5921/5596/8452/5528/7316/9978/3560/4233/5597/84078/3718/6714/4609/5715/5519/2261/3558/3717/2244/3084/2534/5529/1445/998/5894/3563/1742/6233/5527/2885/6709/3716/2266/8660/7514/7311/5518/5155/2243/1956/60/4254/4343/3570/3845/3265/3559/369/801/7297/5781/3569/5245/7314/3572/5879/5595/5515/5516 80 Mumps_virus R-HSA-1227986 Signaling by ERBB2 29/1098 50/10654 1.347530701805855e-16 2.7826508992290906e-15 1.5981241305627336e-15 5295/4893/8065/5290/5335/2065/10273/207/10193/9101/2064/7316/5753/6714/10000/3320/3084/2534/208/6233/2885/7525/7311/387/1956/3845/3265/11140/7314 29 Mumps_virus R-HSA-912631 Regulation of signaling by CBL 19/1098 22/10654 1.7504725407713762e-16 3.5554679967471066e-015 2.0419662425564286e-15 5295/5290/5291/7316/6850/8503/867/4067/2534/6233/2885/7525/1398/7409/7311/5293/5296/1399/7314 19 Mumps_virus R-HSA-8964616 G beta:gamma signalling through CDC42 18/1098 20/10654 2.354634389416305e-16 4.705470981430326e-15 2.702432677836031e-15 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/998/2786/2791/2790/2787 18 Mumps_virus R-HSA-6804757 Regulation of TP53 Degradation 24/1098 36/10654 6.046543294918159e-16 1.189153514667238e-14 6.829512560341982e-15 5170/207/472/7316/890/80196/55615/64223/5519/10000/7157/208/6233/5527/79109/2475/7311/5518/51230/7314/253260/4193/5515/5516 24 Mumps_virus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 19/1098 23/10654 9.095611758653074e-16 1.7337635336878706e-14 9.957301293683368e-15 11065/246184/7321/991/8697/8881/7316/51433/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 19 Mumps_virus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 19/1098 23/10654 9.095611758653074e-16 1.7337635336878706e-14 9.957301293683368e-15 6885/10392/8767/23118/8517/7316/7335/64127/3656/10454/3654/7189/6233/7311/5599/7334/6416/7314/257397 19 Mumps_virus R-HSA-166520 Signaling by NTRKs 41/1098 101/10654 1.2714256649819128e-15 2.3868127256251364e-14 1.3707874793106432e-14 5295/1173/4893/5290/3667/5335/5291/1849/5594/1785/10817/5528/6774/6714/26052/5519/1432/4914/2534/5603/2885/1398/8660/1385/163/1759/5518/387/5296/6197/3845/5600/3265/1399/6300/1020/5781/5879/5595/5515/5516 41 Mumps_virus R-HSA-187037 Signaling by NTRK1 (TRKA) 36/1098 80/10654 1.4058577144581389e-15 2.599787624199454e-14 1.493102615826712e-14 5295/1173/4893/5290/3667/5335/5291/1849/5594/1785/5528/6774/6714/26052/5519/1432/4914/5603/2885/1398/8660/1385/163/1759/5518/387/5296/6197/3845/5600/3265/1399/6300/5595/5515/5516 36 Mumps_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 23/1098 34/10654 1.5151611515811945e-15 2.7607127453075e-14 1.5855246725524578e-14 7321/29110/57506/54476/7706/7323/7316/3093/23586/7322/64135/83737/3661/9246/51191/6233/7311/7318/7187/5300/9641/1540/7314 23 Mumps_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 24/1098 37/10654 1.5541997109290868e-15 2.7908020896248384e-014 1.60280549899018e-14 5170/207/472/7316/890/80196/55615/64223/5519/10000/7157/208/6233/5527/79109/2475/7311/5518/51230/7314/253260/4193/5515/5516 24 Mumps_virus R-HSA-912694 Regulation of IFNA signaling 20/1098 26/10654 1.957270657720692e-15 3.4643690641656244e-14 1.9896465633371247e-14 3443/5777/3441/9021/3449/3444/6772/8651/3451/3448/3440/3454/3716/3452/3456/6773/7297/5781/3446/3445 20 Mumps_virus R-HSA-76002 Platelet activation, signaling and aggregation 72/1098 262/10654 2.029457670281695e-15 3.5415465541958023e-14 2.033970919363122e-14 5295/2788/928/5170/5777/5590/351/5290/54331/5291/5747/59345/51097/5336/2316/207/813/7422/5594/10681/51764/94235/10447/335/51706/55970/5216/6850/2792/6714/8503/4352/146850/1432/3920/27154/2793/4067/23533/2244/9948/5294/2534/2785/2783/2784/1445/2782/998/5894/2786/2885/1398/7410/948/2266/7409/3932/3479/5155/2243/387/5296/213/801/5781/2791/5879/5595/2790/2787/139322 72 Mumps_virus R-HSA-5686938 Regulation of TLR by endogenous ligand 17/1098 19/10654 2.086265703643336e-15 3.5901155650195734e-14 2.0618649351796713e-14 23643/653509/6271/6280/10333/7099/338/7096/6279/3146/2244/929/948/2266/2243/7097/3929 17 Mumps_virus R-HSA-8939211 ESR-mediated signaling 65/1098 223/10654 2.1994373989092016e-15 3.7330177222582207e-14 2.1439360946829424e-14 5295/2788/5170/3725/596/5590/4893/857/5290/54331/2309/5747/59345/5430/207/5594/1027/3315/10681/51764/94235/4318/200845/2100/865/55970/6667/2792/2289/6714/2099/4609/8503/5437/2793/10000/3320/8243/2785/4846/9126/2783/2784/2782/861/23028/2786/208/3326/7514/1385/1025/1386/1956/5296/4343/3845/3265/801/3480/2791/5595/2790/2787/6387 65 Mumps_virus R-HSA-451927 Interleukin-2 family signaling 26/1098 44/10654 2.7439976657438714e-15 4.59434203764413e-14 2.63860941969112e-14 5295/5777/5290/1437/5291/3561/6775/1439/6776/3560/6774/6850/3718/6772/8503/3558/3717/3563/2885/3716/3932/5293/2185/5296/6777/3559 26 Mumps_virus R-HSA-186763 Downstream signal transduction 21/1098 29/10654 3.0160071857280926e-15 4.9168853988382987e-14 2.8238516032578823e-14 5295/4893/5290/5335/5291/4690/5921/6778/6776/6774/6772/6714/2885/1398/5155/5296/3845/6777/3265/1399/5781 21 Mumps_virus R-HSA-933541 TRAF6 mediated IRF7 activation 21/1098 29/10654 3.0160071857280926e-15 4.9168853988382987e-14 2.8238516032578823e-14 3443/3665/3441/29110/57506/3449/7706/3444/23586/3451/3448/64135/3440/3661/7189/10010/3452/9641/3456/3446/3445 21 Mumps_virus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 19/1098 24/10654 3.9453954447238125e-15 6.267108917965133e-14 3.599308125011198e-14 6885/10392/8767/23118/8517/7316/7335/64127/1432/3656/10454/3654/7189/6233/7311/5600/7334/7314/257397 19 Mumps_virus R-HSA-982772 Growth hormone receptor signaling 19/1098 24/10654 3.9453954447238125e-15 6.267108917965133e-14 3.599308125011198e-14 5777/3667/2690/9021/5594/6776/6774/6772/8651/4067/3717/5618/2688/8660/1154/8835/6777/2689/5595 19 Mumps_virus R-HSA-418217 G beta:gamma signalling through PLC beta 17/1098 20/10654 1.2574145203619583e-14 1.9720716338335016e-13 1.1325945579809248e-13 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Mumps_virus R-HSA-198323 AKT phosphorylates targets in the cytosol 14/1098 14/10654 1.4152209462612564e-14 2.1918234405221208e-13 1.2588017890429071e-13 1147/842/572/207/84335/1027/7249/1026/2932/10000/208/2931/23608/4193 14 Mumps_virus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 19/1098 25/10654 1.4856120976941075e-14 2.2447236451743891e-13 1.2891832837499574e-13 11065/246184/7321/991/8697/8881/7316/51433/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 19 Mumps_virus R-HSA-418592 ADP signalling through P2Y purinoceptor 1 19/1098 25/10654 1.4856120976941075e-14 2.2447236451743891e-13 1.2891832837499574e-13 2788/54331/59345/10681/51764/94235/55970/2792/6714/1432/2793/2785/2783/2784/2782/2786/2791/2790/2787 19 Mumps_virus R-HSA-9020702 Interleukin-1 signaling 40/1098 103/10654 1.6943053875976122e-14 2.5292100906427006e-13 1.4525687279847636e-13 8454/1147/8945/1326/351/4790/6885/11213/10392/8767/3553/54472/6500/23118/8517/4615/7316/9978/7335/5970/4792/177/3146/5715/64127/23291/3656/10454/3654/7189/6285/6233/51135/7311/7334/3551/6416/3554/7314/257397 40 Mumps_virus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 16/1098 18/10654 1.8362936364541505e-14 2.705701363384059e-13 1.5539306925344072e-13 23643/3665/29110/7099/7316/929/3661/6233/10010/7311/7187/9641/353376/5781/7314/148022 16 Mumps_virus R-HSA-5684996 MAPK1/MAPK3 signaling 69/1098 255/10654 1.856211589085109e-14 2.705701363384059e-13 1.5539306925344072e-13 2674/4893/1437/3667/2065/3561/5525/5747/3815/5526/1849/7010/1439/5594/2322/10817/2064/5921/8452/5528/7316/9978/3560/4233/84078/3718/6714/5715/5519/2261/3558/3717/2244/3084/2534/5529/1445/5894/3563/1742/6233/5527/2885/6709/3716/2266/8660/7311/5518/5155/2243/1956/60/4254/3570/3845/3265/3559/369/801/7297/5781/3569/5245/7314/3572/5595/5515/5516 69 Mumps_virus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 15/1098 16/10654 2.0867604065924998e-14 3.006390864846636e-13 1.7266218296897556e-13 23643/6885/23118/7099/7316/929/3656/10454/7189/6233/7311/353376/7314/148022/257397 15 Mumps_virus R-HSA-418346 Platelet homeostasis 36/1098 88/10654 5.293509866781252e-14 7.538688189588473e-13 4.329597906768454e-13 2788/5777/54331/5525/59345/5526/10681/51764/94235/338/488/5528/55970/2778/2792/5519/1432/2793/4843/2785/4846/2783/2784/5529/2782/2786/5527/5518/801/5781/4842/2791/2790/5515/2787/5516 36 Mumps_virus R-HSA-500657 Presynaptic function of Kainate receptors 17/1098 21/10654 5.968281215080501e-14 8.40306866532357e-13 4.826026437074664e-13 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Mumps_virus R-HSA-114604 GPVI-mediated activation cascade 22/1098 35/10654 6.312674565490056e-14 8.788094142294584e-13 5.047153171225641e-13 5295/5170/5777/5590/5290/5291/5336/6850/8503/146850/4067/23533/5294/2534/998/7410/7409/3932/387/5296/5781/5879 22 Mumps_virus R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 16/1098 19/10654 1.0517184655599908e-13 1.447865754254254e-12 8.315341318345659e-13 11065/246184/7321/991/8697/8881/51433/51529/7324/64682/29945/10393/51434/51343/29882/996 16 Mumps_virus R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 15/1098 17/10654 1.6045274381242395e-13 2.184625819599926e-12 1.2546680719166986e-12 23643/6885/23118/7099/7316/929/3656/10454/7189/6233/7311/353376/7314/148022/257397 15 Mumps_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 14/1098 15/10654 1.9209762212672519e-13 2.5870538458153532e-12 1.4857893885316507e-12 54106/3665/4615/7316/7335/3654/7189/6233/51311/51135/7311/7334/51284/7314 14 Mumps_virus R-HSA-1236394 Signaling by ERBB4 28/1098 58/10654 2.306086748088572e-13 3.0723026676147753e-12 1.7644761083280986e-12 5295/4893/5290/2670/2065/23118/51741/23385/348/6776/7316/11059/4734/10413/6714/2099/3084/83737/6285/1742/6233/2885/7311/1956/3845/3265/7314/6387 28 Mumps_virus R-HSA-392170 ADP signalling through P2Y purinoceptor 12 17/1098 22/10654 2.374242157108518e-13 3.129453226231334e-12 1.7972986542053287e-12 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Mumps_virus R-HSA-5621481 C-type lectin receptors (CLRs) 46/1098 142/10654 4.55655874184324e-13 5.942711874888184e-12 3.4130013401507266e-12 8454/1147/5170/8945/4893/4790/6885/7321/5336/3553/9039/6500/23118/841/8517/7316/64581/9020/7335/5970/4792/6850/8915/6714/7322/5715/93978/4067/23291/2534/10454/9040/5894/7189/6233/30835/7311/3845/7334/3265/3551/801/997/26253/7314/257397 46 Mumps_virus R-HSA-428930 Thromboxane signalling through TP receptor 17/1098 23/10654 8.228797461667746e-13 1.0620291723964934e-11 6.099415662376533e-12 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Mumps_virus R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 20/1098 32/10654 1.044771541902115e-12 1.334507155068784e-11 7.664303443579273e-12 2788/54331/59345/5594/10681/51764/94235/55970/2792/6714/2793/2785/2783/2784/2782/2786/2791/5595/2790/2787 20 Mumps_virus R-HSA-5218920 VEGFR2 mediated vascular permeability 19/1098 29/10654 1.1208887496737455e-12 1.4171236335160925e-11 8.138784047040302e-12 5170/857/1499/207/57761/55615/64223/10000/3320/4846/208/79109/7410/2475/7409/117145/801/5879/253260 19 Mumps_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 37/1098 101/10654 1.3528939839866592e-12 1.6851621210717134e-11 9.678175046467681e-12 8454/1147/5170/8945/4790/6885/7321/5336/3553/9039/6500/23118/841/8517/7316/64581/9020/7335/5970/4792/6850/8915/6714/7322/5715/23291/10454/9040/7189/6233/7311/7334/3551/801/997/7314/257397 37 Mumps_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 12/1098 12/10654 1.360098564222529e-12 1.6851621210717134e-11 9.678175046467681e-12 3665/29110/7098/7316/3661/6233/10010/7311/7187/9641/7314/148022 12 Mumps_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 14/1098 16/10654 1.3907077485523277e-12 1.706026634115182e-11 9.798003522890815e-12 8454/1147/8945/1326/4790/6500/8517/7316/23291/6233/7311/3551/6416/7314 14 Mumps_virus R-HSA-5673001 RAF/MAP kinase cascade 64/1098 249/10654 2.1409119221119937e-12 2.6005783053889804e-11 1.4935567175930937e-11 2674/4893/1437/3667/2065/3561/5525/5747/3815/5526/1849/7010/1439/5594/2322/10817/2064/5921/8452/5528/7316/9978/3560/4233/84078/3718/6714/5715/5519/2261/3558/3717/2244/3084/2534/5529/1445/5894/3563/1742/6233/5527/2885/6709/3716/2266/8660/7311/5518/5155/2243/1956/60/4254/3845/3265/3559/369/801/5245/7314/5595/5515/5516 64 Mumps_virus R-HSA-9006931 Signaling by Nuclear Receptors 72/1098 299/10654 2.7244427911560212e-12 3.2772666196527284e-11 1.8821904208701795e-11 5295/2788/5170/3725/596/5590/4893/857/5290/54331/2309/5747/59345/5160/5430/207/64241/5594/1027/3315/10681/1737/51764/94235/4318/200845/348/2100/865/55970/6667/2792/2289/6714/2099/4609/8503/5437/2793/10000/3320/5162/8243/2785/4846/9126/2783/2784/2782/861/23028/2786/208/3326/7514/1385/1025/1738/1386/1956/5296/4343/3845/3265/801/29116/3480/2791/5595/2790/2787/6387 72 Mumps_virus R-HSA-912526 Interleukin receptor SHC signaling 18/1098 27/10654 2.8635801091860865e-12 3.4115151493091934e-11 1.9592916536536384e-11 5295/5777/5290/1437/5291/3561/1439/3560/3718/8503/3558/3717/3563/2885/3716/5293/5296/3559 18 Mumps_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 15/1098 19/10654 3.742389035411248e-12 4.374358504598619e-11 2.5122691042085443e-11 5295/4893/5290/5335/7316/867/3320/6233/2885/7311/1956/3845/3265/11140/7314 15 Mumps_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 15/1098 19/10654 3.742389035411248e-12 4.374358504598619e-11 2.5122691042085443e-11 5295/4893/5290/5335/7316/867/3320/6233/2885/7311/1956/3845/3265/11140/7314 15 Mumps_virus R-HSA-1268020 Mitochondrial protein import 28/1098 64/10654 4.81076249296637e-12 5.570593204472274e-11 3.199287206340646e-11 90639/10063/56942/26520/3313/7416/400916/10440/54927/10165/1678/3329/56993/26521/25813/100272147/10469/4580/8604/26517/92609/10651/80273/9804/54543/388753/2671/131474 28 Mumps_virus R-HSA-1059683 Interleukin-6 signaling 11/1098 11/10654 1.3316954019337948e-11 1.4849215647913385e-10 8.528159192888533e-11 9021/6774/6772/867/3717/3716/3570/7297/5781/3569/3572 11 Mumps_virus R-HSA-5603041 IRAK4 deficiency (TLR2/4) 11/1098 11/10654 1.3316954019337948e-11 1.4849215647913385e-10 8.528159192888533e-11 23643/10333/7099/4615/7096/929/114609/695/948/51135/7097 11 Mumps_virus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 11/1098 11/10654 1.3316954019337948e-11 1.4849215647913385e-10 8.528159192888533e-11 6885/23118/7098/7316/10454/7189/6233/7311/7314/148022/257397 11 Mumps_virus R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 30/1098 75/10654 1.3530049705392347e-11 1.4849215647913385e-10 8.528159192888533e-11 5295/5290/3667/5291/2065/3815/941/2064/2100/4233/6714/2099/8503/2261/3084/2534/942/2885/7409/8660/3932/5293/5155/1956/4254/118788/5296/5781/940/5879 30 Mumps_virus R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 15/1098 20/10654 1.3542868185748283e-11 1.4849215647913385e-10 8.528159192888533e-11 11065/246184/7321/991/8697/8881/51433/51529/7324/64682/29945/10393/51434/29882/996 15 Mumps_virus R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 15/1098 20/10654 1.3542868185748283e-11 1.4849215647913385e-10 8.528159192888533e-11 11065/246184/7321/991/8697/8881/51433/51529/7324/64682/29945/10393/51434/29882/996 15 Mumps_virus R-HSA-392518 Signal amplification 19/1098 32/10654 1.4352319837401992e-11 1.546306459003571e-10 8.880703167124713e-11 2788/54331/59345/10681/51764/94235/55970/2792/6714/1432/2793/2785/2783/2784/2782/2786/2791/2790/2787 19 Mumps_virus R-HSA-451326 Activation of kainate receptors upon glutamate binding 19/1098 32/10654 1.4352319837401992e-11 1.546306459003571e-10 8.880703167124713e-11 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/1742/801/2791/2790/2787 19 Mumps_virus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 12/1098 13/10654 1.601572932503123e-11 1.71064557187187e-10 9.824530874520066e-11 2065/207/10193/9101/2064/7316/10000/3084/208/6233/7311/7314 12 Mumps_virus R-HSA-202403 TCR signaling 39/1098 119/10654 1.8565351926473675e-11 1.966023165547084e-10 1.1291208189200365e-10 5295/8454/1147/5170/8945/5290/5335/4790/6885/5291/4690/7321/8767/6500/23118/5788/8517/7316/7335/5970/4792/8915/3113/7322/5715/23291/5728/1445/7189/6233/3702/26191/7311/3932/5296/7334/3551/997/7314 39 Mumps_virus R-HSA-75893 TNF signaling 22/1098 43/10654 1.99575398096535e-11 2.0955416800136176e-10 1.2035055228658136e-10 7124/1147/25999/6885/8737/55072/330/23118/841/8517/7316/329/10616/10454/8567/6233/7311/8772/1540/3551/7314/257397 22 Mumps_virus R-HSA-390466 Chaperonin-mediated protein folding 34/1098 95/10654 2.3459818940707792e-11 2.442581148532517e-10 1.4028162409481176e-10 2788/26224/54331/59345/10681/5203/898/51764/94235/10517/55970/6774/2792/26272/2793/26270/7846/2785/55294/2783/26190/2784/2782/7157/2786/6468/10383/60/54461/26234/2791/84261/2790/2787 34 Mumps_virus R-HSA-9609507 Protein localization 47/1098 163/10654 2.7025261492539762e-11 2.79035824910473e-10 1.6025505937681478e-10 1891/351/90639/10063/7321/51/10965/56942/26520/3313/7416/7323/7316/400916/10440/54927/10165/1678/3329/7322/56993/1962/26521/25813/100272147/118424/10469/4580/8604/4843/10455/26517/92609/10651/8540/6233/4358/6844/80273/9804/7311/54543/388753/2671/3162/131474/7314 47 Mumps_virus R-HSA-5654741 Signaling by FGFR3 21/1098 40/10654 3.0211010294460265e-11 3.0681509635111697e-10 1.7620917134646372e-10 5295/4893/5290/5335/5594/10817/7316/6714/2261/867/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 21 Mumps_virus R-HSA-5675221 Negative regulation of MAPK pathway 21/1098 40/10654 3.0211010294460265e-11 3.0681509635111697e-10 1.7620917134646372e-10 4893/5525/5526/1849/5594/5528/7316/5519/5529/5894/6233/5527/7311/5518/3845/3265/369/7314/5595/5515/5516 21 Mumps_virus R-HSA-420092 Glucagon-type ligand receptors 19/1098 33/10654 3.057797504287274e-11 3.0801716323674244e-10 1.7689953897288812e-10 2788/2692/54331/59345/10681/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 19 Mumps_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 18/1098 30/10654 3.904264382505398e-11 3.901115782196926e-10 2.2404776931864596e-10 7124/1147/6885/8737/55072/330/23118/8517/7316/329/10616/10454/6233/7311/1540/3551/7314/257397 18 Mumps_virus R-HSA-913531 Interferon Signaling 53/1098 199/10654 4.128795523890037e-11 4.092462123279805e-10 2.350371178231297e-10 3443/3665/3460/5777/3441/6737/5335/960/2316/9021/85363/9830/3383/3449/7706/3444/7316/4734/3113/6772/8651/3659/23586/3459/6059/3451/3717/3448/3440/3458/3454/3661/7324/9246/5371/51191/6233/3716/7311/81603/7318/5610/5300/3452/7334/3456/6773/7297/5781/3446/7314/3445/5595 53 Mumps_virus R-HSA-933542 TRAF6 mediated NF-kB activation 16/1098 24/10654 4.830236506826989e-11 4.749732565046539e-10 2.7278528643400546e-10 1147/351/4790/57506/4214/7706/8517/5970/4792/177/3146/23586/64135/7189/6285/3551 16 Mumps_virus R-HSA-1295596 Spry regulation of FGF signaling 13/1098 16/10654 5.768082706220018e-11 5.583323807036408e-10 3.2065986097078393e-10 5594/7316/6714/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 13 Mumps_virus R-HSA-1433559 Regulation of KIT signaling 13/1098 16/10654 5.768082706220018e-11 5.583323807036408e-10 3.2065986097078393e-10 5777/3815/10019/9306/6714/8651/867/4067/2534/2885/7525/3932/4254 13 Mumps_virus R-HSA-8852135 Protein ubiquitination 30/1098 79/10654 6.376690390671582e-11 6.124588677552007e-10 3.517456306890241e-10 11065/7319/7321/65264/7320/10477/92912/7336/7326/5591/7323/7316/7317/54926/55236/8915/3093/7322/7347/118424/7328/7324/6233/7327/7311/55284/27338/7334/997/7314 30 Mumps_virus R-HSA-5689896 Ovarian tumor domain proteases 20/1098 38/10654 8.462308449382963e-11 8.065230899065762e-10 4.632000414399096e-10 7321/8737/10392/8767/57506/7706/8517/7316/2099/23586/64127/64135/5728/7157/7189/6233/7311/7187/387/7314 20 Mumps_virus R-HSA-176412 Phosphorylation of the APC/C 14/1098 19/10654 9.989376889134785e-11 9.447967912700761e-10 5.426129993616004e-10 11065/246184/7321/8697/8881/51433/51529/7324/64682/29945/10393/51434/29882/996 14 Mumps_virus R-HSA-202040 G-protein activation 17/1098 28/10654 1.058071672613111e-10 9.856772950132666e-10 5.660913737130694e-10 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Mumps_virus R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 17/1098 28/10654 1.058071672613111e-10 9.856772950132666e-10 5.660913737130694e-10 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Mumps_virus R-HSA-5602498 MyD88 deficiency (TLR2/4) 10/1098 10/10654 1.302809361965376e-10 1.1956894810926673e-9 6.86704973636331e-10 23643/10333/7099/4615/7096/929/114609/695/948/7097 10 Mumps_virus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 10/1098 10/10654 1.302809361965376e-10 1.1956894810926673e-9 6.86704973636331e-10 6885/23118/7316/3656/10454/7189/6233/7311/7314/257397 10 Mumps_virus R-HSA-9020558 Interleukin-2 signaling 11/1098 12/10654 1.4484236402560655e-10 1.3099247374286607e-9 7.523122403481371e-10 3561/6776/3560/6850/3718/3558/3716/3932/2185/6777/3559 11 Mumps_virus R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 11/1098 12/10654 1.4484236402560655e-10 1.3099247374286607e-9 7.523122403481371e-10 5295/5290/5291/4067/23533/3717/5294/2057/2056/8660/5293 11 Mumps_virus R-HSA-391251 Protein folding 34/1098 101/10654 1.612844827317786e-10 1.4480541601787946e-9 8.31642336587966e-10 2788/26224/54331/59345/10681/5203/898/51764/94235/10517/55970/6774/2792/26272/2793/26270/7846/2785/55294/2783/26190/2784/2782/7157/2786/6468/10383/60/54461/26234/2791/84261/2790/2787 34 Mumps_virus R-HSA-5673000 RAF activation 18/1098 32/10654 1.7393464353417092e-10 1.5503958513585452e-9 8.904189248701217e-10 4893/5525/5526/5528/6714/5519/3717/5529/5894/5527/5518/3845/3265/369/801/5245/5515/5516 18 Mumps_virus R-HSA-432142 Platelet sensitization by LDL 13/1098 17/10654 2.2196484725966527e-10 1.9643888982480374e-9 1.128182231184464e-9 5777/5525/5526/338/5528/5519/1432/5529/5527/5518/5781/5515/5516 13 Mumps_virus R-HSA-8863795 Downregulation of ERBB2 signaling 17/1098 29/10654 2.3122803699406315e-10 2.0318548782669805e-9 1.1669291004702257e-9 8065/2065/10273/207/10193/9101/2064/7316/10000/3320/3084/208/6233/7311/1956/11140/7314 17 Mumps_virus R-HSA-202424 Downstream TCR signaling 33/1098 98/10654 2.972187646650536e-10 2.593338376197193e-9 1.489398702102122e-9 5295/8454/1147/5170/8945/5290/4790/6885/5291/7321/8767/6500/23118/8517/7316/7335/5970/4792/8915/3113/7322/5715/23291/5728/7189/6233/7311/3932/5296/7334/3551/997/7314 33 Mumps_virus R-HSA-5357801 Programmed Cell Death 48/1098 181/10654 4.0614942369451095e-10 3.519014936765728e-9 2.021030625082734e-9 23643/2934/11035/596/1499/4976/10018/5747/7027/842/572/8737/7532/207/10971/5594/10059/355/330/7533/841/7099/7316/6774/5339/4836/115209/3146/5715/329/598/836/929/10000/7157/208/6233/6709/7311/8772/5599/353376/7431/26060/8743/7314/5595/148022 48 Mumps_virus R-HSA-1170546 Prolactin receptor signaling 12/1098 15/10654 4.599951472419046e-10 3.9578749127272205e-9 2.2730754352012247e-9 8454/8945/2690/6500/6776/9978/3717/5618/2688/6777/2689/5781 12 Mumps_virus R-HSA-2424491 DAP12 signaling 17/1098 30/10654 4.825473972919987e-10 4.123284312033009e-9 2.368072889795943e-9 5295/4893/5290/5335/5291/5336/54209/6850/2534/695/2885/7410/3932/5296/3845/3265/5879 17 Mumps_virus R-HSA-5654743 Signaling by FGFR4 20/1098 41/10654 5.006991053951463e-10 4.2490835040040156e-9 2.440321523050606e-9 5295/4893/5290/5335/5594/10817/7316/6714/867/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 20 Mumps_virus R-HSA-2559583 Cellular Senescence 50/1098 195/10654 6.307875457661257e-10 5.316637885743059e-9 3.0534363117644185e-9 3725/11065/4790/9448/246184/7027/7321/6045/8697/5594/1027/898/7295/472/3576/8881/7316/890/6774/5970/1026/6667/51433/1031/1432/23512/7157/51529/7324/64682/29945/10393/6233/51434/51343/7311/4343/6197/29882/5599/648/5600/4217/3456/6416/3569/7314/996/5595/4193 50 Mumps_virus R-HSA-74751 Insulin receptor signalling cascade 23/1098 54/10654 7.526502426282465e-10 6.3009030447053875e-9 3.6187166715269894e-9 5295/54106/5170/3643/4893/5290/3667/5291/5594/2322/57761/5140/2261/3630/208/2885/8660/5296/117145/3845/3265/5781/5595 23 Mumps_virus R-HSA-2586552 Signaling by Leptin 10/1098 11/10654 1.2999207579685444e-9 1.0809408182033735e-8 6.2080284873665574e-009 3667/3953/9021/3952/6776/6774/3717/8660/6777/5781 10 Mumps_virus R-HSA-73887 Death Receptor Signalling 40/1098 141/10654 1.3949107309232728e-9 1.1521962637426232e-8 6.617260730555316e-9 7124/1147/25999/4790/6885/10018/572/8737/8767/55072/355/330/23118/23385/841/8517/4615/7316/5970/4792/329/836/10616/10454/8567/3654/7189/6233/7410/7409/7311/387/8772/5599/1540/3551/8743/7314/5879/257397 40 Mumps_virus R-HSA-193639 p75NTR signals via NF-kB 12/1098 16/10654 1.6669381077810178e-9 1.367772394397802e-8 7.855351417636585e-9 4790/8767/4615/7316/5970/4792/3654/7189/6233/7311/3551/7314 12 Mumps_virus R-HSA-1643713 Signaling by EGFR in Cancer 15/1098 25/10654 1.7314114538266324e-9 1.4113281521652616e-8 8.10549960378673e-9 5295/4893/5290/5335/7316/867/3320/6233/2885/7311/1956/3845/3265/11140/7314 15 Mumps_virus R-HSA-2871796 FCERI mediated MAPK activation 17/1098 32/10654 1.8642967520054945e-9 1.5097148207417044e-8 8.670551113558408e-9 3725/4893/5335/5336/5594/4214/6850/4067/2885/7410/7409/3845/5599/3265/6416/5879/5595 17 Mumps_virus R-HSA-2428928 IRS-related events triggered by IGF1R 22/1098 52/10654 2.0595003711154476e-9 1.65696166221561e-8 9.516214975215604e-9 5295/54106/5170/4893/5290/3667/5291/2322/57761/5140/2261/8471/208/2885/8660/3479/5296/117145/3845/3265/5781/3480 22 Mumps_virus R-HSA-109581 Apoptosis 46/1098 178/10654 2.3405505598266326e-9 1.870930415242063e-8 1.0745074216929059e-8 23643/2934/596/1499/4976/10018/5747/7027/842/572/8737/7532/207/10971/5594/10059/355/7533/841/7099/7316/6774/5339/4836/115209/3146/5715/329/598/836/929/10000/7157/208/6233/6709/7311/8772/5599/353376/7431/26060/8743/7314/5595/148022 46 Mumps_virus R-HSA-69231 Cyclin D associated events in G1 20/1098 44/10654 2.4190963761332165e-9 1.909083063712774e-8 1.0964191419819341e-8 8454/25/7027/1027/6500/7316/5753/1026/6714/1031/5519/4067/3717/6502/6233/7311/5518/7314/5515/5516 20 Mumps_virus R-HSA-69236 G1 Phase 20/1098 44/10654 2.4190963761332165e-9 1.909083063712774e-8 1.0964191419819341e-8 8454/25/7027/1027/6500/7316/5753/1026/6714/1031/5519/4067/3717/6502/6233/7311/5518/7314/5515/5516 20 Mumps_virus R-HSA-3700989 Transcriptional Regulation by TP53 75/1098 365/10654 2.7138288062990523e-9 2.1281227158256493e-8 1.2222173704584674e-8 9377/23774/834/5170/3725/64769/7862/7027/5430/7532/207/10971/1027/58484/7249/898/355/7295/7533/4292/545/472/7316/890/80196/84289/1026/55615/6341/8148/64223/9150/5519/1432/27154/5437/51499/10000/51755/5728/6009/7994/7157/55215/5371/208/6233/5527/79109/2968/2475/1025/7311/51204/5518/6834/1386/5300/4343/6117/1340/1327/5600/4697/5564/51230/1020/2744/57521/7248/7314/253260/4193/5515/5516 75 Mumps_virus R-HSA-2428924 IGF1R signaling cascade 22/1098 53/10654 3.1816757545465792e-9 2.4793058238259192e-8 1.423907851753385e-8 5295/54106/5170/4893/5290/3667/5291/2322/57761/5140/2261/8471/208/2885/8660/3479/5296/117145/3845/3265/5781/3480 22 Mumps_virus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 29/1098 86/10654 3.4259971993650697e-9 2.653006581258326e-8 1.523667175507097e-8 5295/25/5290/5335/5291/5747/4690/5336/4771/5594/4644/6850/6714/4067/3320/2534/998/695/2885/7525/1398/7410/10096/3326/7409/60/5296/5879/5595 29 Mumps_virus R-HSA-5357905 Regulation of TNFR1 signaling 17/1098 33/10654 3.4775267399298497e-9 2.676183621598189e-8 1.5369781472328072e-8 7124/1147/25999/8737/55072/330/841/8517/7316/329/10616/8567/6233/7311/1540/3551/7314 17 Mumps_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 34/1098 112/10654 3.5339239886575094e-9 2.7027974209547246e-8 1.5522629085981005e-8 5295/8454/1147/5777/8945/4893/4790/6885/5966/4690/5336/6500/8517/7316/5970/4792/6850/8915/5715/4067/23291/2534/695/6233/2885/7409/7311/5293/118788/3845/3265/3551/801/7314 34 Mumps_virus R-HSA-9027284 Erythropoietin activates RAS 11/1098 14/10654 3.610112573105308e-9 2.7441285141579614e-8 1.5760000642035446e-8 4893/4067/3717/2057/2885/2056/7409/8660/3845/3265/1399 11 Mumps_virus R-HSA-2871837 FCERI mediated NF-kB activation 28/1098 82/10654 4.631939324719294e-9 3.4993736727604906e-8 2.0097503103403356e-8 8454/1147/5170/8945/4790/6885/7321/6500/23118/8517/7316/7335/5970/4792/8915/7322/5715/4067/23291/10454/7189/6233/7311/7334/3551/997/7314/257397 28 Mumps_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 24/1098 63/10654 4.85108840607575e-9 3.578077710567953e-8 2.0549513889332964e-8 1147/3665/11035/6737/4790/1499/8737/29110/8517/6778/4615/7098/5591/7316/5970/4792/5437/22954/3661/6233/7311/3551/7314/148022 24 Mumps_virus R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 22/1098 54/10654 4.851630793990444e-9 3.578077710567953e-8 2.0549513889332964e-8 5295/54106/5170/4893/5290/3667/5291/2322/57761/5140/2261/8471/208/2885/8660/3479/5296/117145/3845/3265/5781/3480 22 Mumps_virus R-HSA-8848021 Signaling by PTK6 22/1098 54/10654 4.851630793990444e-9 3.578077710567953e-8 2.0549513889332964e-8 4893/2065/207/9021/1027/898/2064/5921/7316/5753/6774/867/3084/6233/1398/7311/387/1956/3845/3265/7314/5879 22 Mumps_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 22/1098 54/10654 4.851630793990444e-9 3.578077710567953e-8 2.0549513889332964e-8 4893/2065/207/9021/1027/898/2064/5921/7316/5753/6774/867/3084/6233/1398/7311/387/1956/3845/3265/7314/5879 22 Mumps_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 26/1098 73/10654 5.94711949502326e-9 4.3600479611442714e-8 2.5040503136940044e-8 57154/5590/892/7027/7321/6497/10273/4738/64750/7323/54778/7316/6667/4609/23327/867/4088/142/9040/4087/6233/7514/1025/7311/387/7314 26 Mumps_virus R-HSA-5696394 DNA Damage Recognition in GG-NER 18/1098 38/10654 6.768916175674377e-9 4.933345377447384e-8 2.8333048512420306e-8 9318/8450/7316/9978/64708/10980/10920/142/10987/6233/2873/7311/60/8533/50813/7314/51138/8451 18 Mumps_virus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 10/1098 12/10654 7.075312727683185e-9 5.126498520233606e-8 2.9442360134895865e-8 1147/8737/57506/841/7706/8517/23586/64135/8772/3551 10 Mumps_virus R-HSA-2562578 TRIF-mediated programmed cell death 9/1098 10/10654 1.1562462995830298e-8 8.329006774321942e-8 4.7834914229995614e-8 23643/11035/8737/841/7099/929/8772/353376/148022 9 Mumps_virus R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 11/1098 15/10654 1.2272935494229672e-8 8.355036855687123e-8 4.7984409451123537e-8 1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 11 Mumps_virus R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 11/1098 15/10654 1.2272935494229672e-8 8.355036855687123e-8 4.7984409451123537e-8 1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 11 Mumps_virus R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 11/1098 15/10654 1.2272935494229672e-8 8.355036855687123e-8 4.7984409451123537e-8 1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 11 Mumps_virus R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 11/1098 15/10654 1.2272935494229672e-8 8.355036855687123e-8 4.7984409451123537e-8 1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 11 Mumps_virus R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 11/1098 15/10654 1.2272935494229672e-8 8.355036855687123e-8 4.7984409451123537e-8 1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 11 Mumps_virus R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 11/1098 15/10654 1.2272935494229672e-8 8.355036855687123e-8 4.7984409451123537e-8 1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 11 Mumps_virus R-HSA-5637810 Constitutive Signaling by EGFRvIII 11/1098 15/10654 1.2272935494229672e-8 8.355036855687123e-8 4.7984409451123537e-8 5295/4893/5290/5335/867/3320/2885/1956/3845/3265/11140 11 Mumps_virus R-HSA-5637812 Signaling by EGFRvIII in Cancer 11/1098 15/10654 1.2272935494229672e-8 8.355036855687123e-8 4.7984409451123537e-8 5295/4893/5290/5335/867/3320/2885/1956/3845/3265/11140 11 Mumps_virus R-HSA-937039 IRAK1 recruits IKK complex 11/1098 15/10654 1.2272935494229672e-8 8.355036855687123e-8 4.7984409451123537e-8 1147/8517/7316/7335/3654/7189/6233/7311/7334/3551/7314 11 Mumps_virus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 11/1098 15/10654 1.2272935494229672e-8 8.355036855687123e-8 4.7984409451123537e-8 1147/8517/7316/7335/3654/7189/6233/7311/7334/3551/7314 11 Mumps_virus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 13/1098 21/10654 1.2762094316108853e-8 8.640565495988454e-8 4.962424939712158e-8 1147/11035/4790/8737/29110/8517/4615/7098/5970/4792/3661/3551/148022 13 Mumps_virus R-HSA-209560 NF-kB is activated and signals survival 10/1098 13/10654 2.7815058970364538e-8 1.872981416537047e-7 1.0756853469088346e-7 4790/7316/5970/4792/3654/7189/6233/7311/3551/7314 10 Mumps_virus R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 32/1098 110/10654 3.186629613074747e-8 2.1341805895133035e-7 1.225696511202577e-7 3725/11065/4790/246184/7321/8697/5594/1027/3576/8881/7316/890/6774/5970/1026/51433/1031/51529/7324/64682/29945/10393/6233/51434/51343/7311/6197/29882/3569/7314/996/5595 32 Mumps_virus R-HSA-5654736 Signaling by FGFR1 20/1098 50/10654 3.531671302299207e-8 2.352548786854149e-7 1.3511091116888875e-7 5295/4893/5290/5335/5594/10817/7316/6714/867/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 20 Mumps_virus R-HSA-909733 Interferon alpha/beta signaling 24/1098 69/10654 3.8829424477206086e-8 2.572708926591355e-7 1.477550855423097e-7 3443/3665/5777/3441/9021/3449/3444/6772/8651/3659/6059/3451/3448/3440/3454/3661/3716/3452/3456/6773/7297/5781/3446/3445 24 Mumps_virus R-HSA-6806834 Signaling by MET 26/1098 79/10654 3.9116903991539466e-8 2.577970427953053e-7 1.4805726258835767e-7 5295/4893/5290/85440/5747/9101/3688/7316/6774/4233/6714/3673/867/9146/3914/6233/2885/1398/7311/3845/3265/1399/5781/53916/7314/5879 26 Mumps_virus R-HSA-611105 Respiratory electron transport 30/1098 100/10654 3.963034879368143e-8 2.597989532030227e-7 1.4920699406587944e-7 51300/9377/4722/4723/4702/7388/4719/55863/4704/2109/51295/4729/7386/6389/6341/7385/4728/4725/27089/2108/4726/7384/51204/6834/4698/1340/1327/4697/4720/51079 30 Mumps_virus R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 18/1098 42/10654 4.768081777605061e-8 3.109291222343511e-7 1.7857192696182946e-7 2788/54331/59345/10681/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 18 Mumps_virus R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 9/1098 11/10654 5.774390306620808e-8 3.7457955968079484e-7 2.1512746471621202e-7 6885/23118/7316/10454/7189/6233/7311/7314/257397 9 Mumps_virus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 13/1098 23/10654 5.885728255717972e-8 3.798134015018004e-7 2.181333498281442e-7 7321/6497/64750/7323/54778/7316/23327/4088/142/4087/6233/7311/7314 13 Mumps_virus R-HSA-2262752 Cellular responses to stress 87/1098 479/10654 7.00265566949009e-8 4.495487240672654e-7 2.581835414548842e-7 3725/11065/4790/9448/246184/112399/7027/526/7321/6045/7422/8697/5594/3308/84335/1027/898/7295/10294/545/472/3576/3313/8881/7323/7316/9978/890/10935/6774/5970/1026/832/6667/2289/51433/64223/1031/7322/5715/1432/2932/7846/3310/529/3320/23512/6009/3301/25994/7428/7157/8453/51529/50507/7324/64682/29945/10393/6233/2056/51434/3326/2475/51343/7311/10383/23411/4343/6117/6197/29882/5599/648/5600/54583/3312/4217/3456/6416/1536/3569/57521/7314/996/5595/4193 87 Mumps_virus R-HSA-2172127 DAP12 interactions 18/1098 43/10654 7.416801458230862e-8 4.7125215419220704e-7 2.706481935635122e-7 5295/4893/5290/5335/5291/5336/54209/6850/54210/2534/695/2885/7410/3932/5296/3845/3265/5879 18 Mumps_virus R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 18/1098 43/10654 7.416801458230862e-8 4.7125215419220704e-7 2.706481935635122e-7 2788/54331/59345/10681/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 18 Mumps_virus R-HSA-5213460 RIPK1-mediated regulated necrosis 12/1098 20/10654 7.776704513531321e-8 4.891033955464623e-7 2.8090046760070394e-7 11035/8737/355/330/841/7316/329/6233/7311/8772/8743/7314 12 Mumps_virus R-HSA-5218859 Regulated Necrosis 12/1098 20/10654 7.776704513531321e-8 4.891033955464623e-7 2.8090046760070394e-7 11035/8737/355/330/841/7316/329/6233/7311/8772/8743/7314 12 Mumps_virus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 15/1098 31/10654 8.745476261190959e-8 5.312508715038448e-7 3.0510648582184205e-7 3725/1849/5594/5528/5519/1432/1385/5518/1386/6197/5599/5600/5595/5515/5516 15 Mumps_virus R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 10/1098 14/10654 8.832742496351253e-8 5.312508715038448e-7 3.0510648582184205e-7 5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 10 Mumps_virus R-HSA-4839744 truncated APC mutants destabilize the destruction complex 10/1098 14/10654 8.832742496351253e-8 5.312508715038448e-7 3.0510648582184205e-7 5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 10 Mumps_virus R-HSA-4839748 AMER1 mutants destabilize the destruction complex 10/1098 14/10654 8.832742496351253e-8 5.312508715038448e-7 3.0510648582184205e-7 5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 10 Mumps_virus R-HSA-5467337 APC truncation mutants have impaired AXIN binding 10/1098 14/10654 8.832742496351253e-8 5.312508715038448e-7 3.0510648582184205e-7 5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 10 Mumps_virus R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 10/1098 14/10654 8.832742496351253e-8 5.312508715038448e-7 3.0510648582184205e-7 5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 10 Mumps_virus R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 10/1098 14/10654 8.832742496351253e-8 5.312508715038448e-7 3.0510648582184205e-7 5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 10 Mumps_virus R-HSA-877312 Regulation of IFNG signaling 10/1098 14/10654 8.832742496351253e-8 5.312508715038448e-7 3.0510648582184205e-7 3460/5777/9021/6772/8651/3459/3717/3458/3716/5781 10 Mumps_virus R-HSA-918233 TRAF3-dependent IRF activation pathway 10/1098 14/10654 8.832742496351253e-8 5.312508715038448e-7 3.0510648582184205e-7 3665/29110/57506/7706/23586/64135/3661/7187/9641/3456 10 Mumps_virus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 11/1098 17/10654 9.14700987319546e-8 5.448627515812103e-7 3.129240219777394e-7 1147/11035/4790/8737/8517/4615/7098/5970/4792/3551/148022 11 Mumps_virus R-HSA-196299 Beta-catenin phosphorylation cascade 11/1098 17/10654 9.14700987319546e-8 5.448627515812103e-7 3.129240219777394e-7 1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 11 Mumps_virus R-HSA-4086398 Ca2+ pathway 22/1098 62/10654 9.48867617944315e-8 5.59934548318352e-7 3.2158001330717136e-7 2788/54331/6885/1499/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/4343/3845/801/2791/2790/2787 22 Mumps_virus R-HSA-112399 IRS-mediated signalling 19/1098 48/10654 9.490416073192407e-8 5.59934548318352e-7 3.2158001330717136e-7 5295/54106/5170/4893/5290/3667/5291/2322/57761/5140/2261/208/2885/8660/5296/117145/3845/3265/5781 19 Mumps_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 20/1098 53/10654 1.1203405838411954e-7 6.578682385683607e-7 3.778250110634314e-7 596/10018/7027/842/572/7532/207/10971/5594/7533/841/6774/4836/598/836/10000/7157/208/5599/5595 20 Mumps_virus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 18/1098 44/10654 1.1351516278373644e-7 6.634211636275918e-7 3.8101415115097247e-7 892/7027/7321/6497/64750/7323/54778/7316/6667/4609/23327/4088/142/4087/6233/1025/7311/7314 18 Mumps_virus R-HSA-186797 Signaling by PDGF 21/1098 58/10654 1.2442253612817423e-7 7.237536256469852e-7 4.156641187182891e-7 5295/4893/5290/5335/5291/4690/5921/6778/6776/6774/6772/6714/2885/1398/5155/5296/3845/6777/3265/1399/5781 21 Mumps_virus R-HSA-74752 Signaling by Insulin receptor 25/1098 78/10654 1.282627414623279e-7 7.426053115505807e-7 4.2649096521659454e-7 5295/54106/5170/3643/4893/5290/3667/5291/526/5594/2322/57761/5140/2261/529/3630/208/2885/8660/5296/117145/3845/3265/5781/5595 25 Mumps_virus R-HSA-5633007 Regulation of TP53 Activity 39/1098 160/10654 2.0908350361447298e-7 1.197602977821791e-6 6.878039276220474e-7 23774/5170/64769/7862/207/545/472/7316/890/80196/84289/55615/8148/64223/5519/1432/27154/10000/7994/7157/5371/208/6233/5527/79109/2475/7311/5518/5300/6117/5600/5564/51230/1020/7314/253260/4193/5515/5516 39 Mumps_virus R-HSA-389359 CD28 dependent Vav1 pathway 9/1098 12/10654 2.097496740817826e-7 1.197602977821791e-6 6.878039276220474e-7 941/2534/998/942/2885/7409/3932/940/5879 9 Mumps_virus R-HSA-8984722 Interleukin-35 Signalling 9/1098 12/10654 2.097496740817826e-7 1.197602977821791e-6 6.878039276220474e-7 3592/6775/3595/6774/6772/3717/3716/7297/3572 9 Mumps_virus R-HSA-210993 Tie2 Signaling 11/1098 18/10654 2.132755939054977e-7 1.2066139764790485e-6 6.929790986787621e-7 5295/4893/5290/5291/7010/2888/2885/5296/3845/3265/5781 11 Mumps_virus R-HSA-5675482 Regulation of necroptotic cell death 11/1098 18/10654 2.132755939054977e-7 1.2066139764790485e-6 6.929790986787621e-7 8737/355/330/841/7316/329/6233/7311/8772/8743/7314 11 Mumps_virus R-HSA-1296041 Activation of G protein gated Potassium channels 13/1098 25/10654 2.1950326523052808e-7 1.2195719534557143e-6 7.004210870702714e-7 2788/54331/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 13 Mumps_virus R-HSA-1296059 G protein gated Potassium channels 13/1098 25/10654 2.1950326523052808e-7 1.2195719534557143e-6 7.004210870702714e-7 2788/54331/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 13 Mumps_virus R-HSA-9006115 Signaling by NTRK2 (TRKB) 13/1098 25/10654 2.1950326523052808e-7 1.2195719534557143e-6 7.004210870702714e-7 5295/4893/5290/5335/10817/6714/2534/2885/3845/3265/1020/5781/5879 13 Mumps_virus R-HSA-997272 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits 13/1098 25/10654 2.1950326523052808e-7 1.2195719534557143e-6 7.004210870702714e-7 2788/54331/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 13 Mumps_virus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 25/1098 80/10654 2.2279950689688993e-7 1.2323597725234223e-6 7.077653508566618e-7 8454/8945/11065/246184/7321/991/8697/6500/8881/7316/890/51433/5715/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/7314/996 25 Mumps_virus R-HSA-5654732 Negative regulation of FGFR3 signaling 14/1098 29/10654 2.4632116370415134e-7 1.3555699324456054e-6 7.78527058606881e-7 5594/7316/6714/2261/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 14 Mumps_virus R-HSA-163359 Glucagon signaling in metabolic regulation 15/1098 33/10654 2.472629578149369e-7 1.3555699324456054e-6 7.78527058606881e-7 2788/54331/59345/51764/94235/55970/2778/2785/2783/2784/2782/2786/2791/2790/2787 15 Mumps_virus R-HSA-69242 S Phase 39/1098 161/10654 2.4910290231866514e-7 1.3596409514221414e-6 7.808651146182131e-7 8454/11065/246184/7027/7321/207/8697/1027/6500/898/8881/7316/5422/9978/5753/890/1026/4609/51433/5715/2932/6502/10000/8243/9126/51529/7324/64682/29945/10393/208/6233/51434/51343/7311/6117/29882/7314/996 39 Mumps_virus R-HSA-8953897 Cellular responses to external stimuli 87/1098 493/10654 2.6406550915966054e-7 1.434987569512366e-6 8.241379694918309e-7 3725/11065/4790/9448/246184/112399/7027/526/7321/6045/7422/8697/5594/3308/84335/1027/898/7295/10294/545/472/3576/3313/8881/7323/7316/9978/890/10935/6774/5970/1026/832/6667/2289/51433/64223/1031/7322/5715/1432/2932/7846/3310/529/3320/23512/6009/3301/25994/7428/7157/8453/51529/50507/7324/64682/29945/10393/6233/2056/51434/3326/2475/51343/7311/10383/23411/4343/6117/6197/29882/5599/648/5600/54583/3312/4217/3456/6416/1536/3569/57521/7314/996/5595/4193 87 Mumps_virus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 26/1098 86/10654 2.672346103797341e-7 1.4395812272195244e-6 8.267761858887885e-7 8454/8945/11065/246184/7321/991/8697/6500/8881/7316/890/51433/5715/6502/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/7314/996 26 Mumps_virus R-HSA-453276 Regulation of mitotic cell cycle 26/1098 86/10654 2.672346103797341e-7 1.4395812272195244e-6 8.267761858887885e-7 8454/8945/11065/246184/7321/991/8697/6500/8881/7316/890/51433/5715/6502/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/7314/996 26 Mumps_virus R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 17/1098 42/10654 3.077012918815183e-7 1.650397838273598e-6 9.478517808699313e-7 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Mumps_virus R-HSA-110056 MAPK3 (ERK1) activation 8/1098 10/10654 4.625305805271176e-7 2.4490401250987123e-6 1.4065257419538081e-6 3717/3716/3570/7297/5781/3569/3572/5595 8 Mumps_virus R-HSA-8877330 RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) 8/1098 10/10654 4.625305805271176e-7 2.4490401250987123e-6 1.4065257419538081e-6 1378/865/3558/50943/3458/861/3559/1493 8 Mumps_virus R-HSA-9020958 Interleukin-21 signaling 8/1098 10/10654 4.625305805271176e-7 2.4490401250987123e-6 1.4065257419538081e-6 3561/6775/6776/6774/3718/6772/3716/6777 8 Mumps_virus R-HSA-418597 G alpha (z) signalling events 18/1098 48/10654 5.393757982916946e-7 2.8437728258868496e-6 1.6332275012102378e-6 2788/54331/59345/10681/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 18 Mumps_virus R-HSA-209543 p75NTR recruits signalling complexes 9/1098 13/10654 6.191025580824746e-7 3.2481996305968946e-6 1.8654967505913095e-6 8767/4615/7316/3654/7189/6233/7311/3551/7314 9 Mumps_virus R-HSA-8949215 Mitochondrial calcium ion transport 12/1098 23/10654 6.213263215911735e-7 3.2481996305968946e-6 1.8654967505913095e-6 10730/11331/8165/7416/7417/6687/30968/3954/221154/10367/10939/5245 12 Mumps_virus R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 13/1098 27/10654 6.948101797971284e-7 3.6171000536497566e-6 2.0773625897516976e-6 23643/842/8737/355/841/7099/836/929/8772/353376/26060/8743/148022 13 Mumps_virus R-HSA-69052 Switching of origins to a post-replicative state 26/1098 90/10654 7.16027977625502e-7 3.711960938401661e-6 2.131842822615457e-6 8454/11065/246184/7321/8697/6500/898/8881/7316/9978/890/51433/5715/6502/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/7314/996 26 Mumps_virus R-HSA-1428517 The citric acid (TCA) cycle and respiratory electron transport 40/1098 174/10654 7.631772219573748e-7 3.939902408354947e-6 2.2627535177332692e-6 51300/9377/4967/4722/4723/4702/5160/7388/1743/4719/55863/4704/2109/4200/1737/51295/4729/7386/7416/6389/6341/7385/4728/4725/682/5162/27089/2108/3029/4726/7384/1738/51204/6834/4698/1340/1327/4697/4720/51079 40 Mumps_virus R-HSA-177929 Signaling by EGFR 18/1098 49/10654 7.711760049583427e-7 3.964676639599115e-6 2.276981783585236e-6 5295/4893/5290/5335/7316/6714/867/9146/1445/998/6233/2885/7311/1956/3845/3265/5781/7314 18 Mumps_virus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 19/1098 54/10654 8.257617190272672e-7 4.227763511879273e-6 2.428077085960995e-6 9318/5430/8450/7316/9978/64708/10980/5437/10920/10987/6233/2873/2968/7311/8533/50813/7314/51138/8451 19 Mumps_virus R-HSA-163685 Integration of energy metabolism 29/1098 108/10654 9.026948207401282e-7 4.599057275993566e-6 2.6413174619358996e-6 2788/54331/59345/10681/51764/94235/4082/5528/55970/2778/2792/5519/2793/2785/2783/2784/2782/3630/2786/9370/948/6844/5518/31/2791/2790/5515/2787/5516 29 Mumps_virus R-HSA-111885 Opioid Signalling 26/1098 91/10654 9.057061947880791e-7 4.599057275993566e-6 2.6413174619358996e-6 2788/54331/59345/5594/10681/51764/94235/5528/55970/2792/5519/2793/2785/2783/2784/2782/2786/1385/5518/801/1020/2791/2790/5515/2787/5516 26 Mumps_virus R-HSA-622312 Inflammasomes 11/1098 20/10654 9.256819755387642e-7 4.68130599058175e-6 2.688554309190998e-6 834/596/351/4790/10910/58484/7295/5970/598/3326/114548 11 Mumps_virus R-HSA-1266695 Interleukin-7 signaling 15/1098 36/10654 9.846881754769277e-7 4.959466054536233e-6 2.848306404032534e-6 5295/3667/3561/6776/6774/3718/8651/8503/3716/8660/1154/3575/5296/8835/6777 15 Mumps_virus R-HSA-5628897 TP53 Regulates Metabolic Genes 25/1098 86/10654 1.026609917854263e-6 5.1496748510989135e-6 2.9575465777518937e-6 9377/7532/207/10971/7249/7295/7533/6341/64223/10000/5728/6009/7157/208/2475/51204/6834/4343/1340/1327/4697/5564/2744/57521/7248 25 Mumps_virus R-HSA-5688426 Deubiquitination 58/1098 297/10654 1.054887238321112e-6 5.270182614031685e-6 3.026756252568217e-6 6885/90865/7321/991/8737/10392/8767/4738/9817/57506/4303/91833/6478/1080/330/9101/4287/7706/8517/64750/7416/29086/7316/890/7417/4792/8678/2099/4609/23586/5715/64127/329/6502/7347/4088/9146/64135/5728/10454/8473/7157/9929/4087/63891/7189/57599/6233/9804/7311/114548/7187/387/60/7345/1540/7314/4193 58 Mumps_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 14/1098 32/10654 1.111851834056844e-6 5.527282729518481e-6 3.174413257851827e-6 57154/10273/4738/64750/7316/23327/867/4088/9040/4087/6233/7514/7311/7314 14 Mumps_virus R-HSA-9614085 FOXO-mediated transcription 21/1098 65/10654 1.1152709300884746e-6 5.527282729518481e-6 3.174413257851827e-6 2308/857/2309/10018/7532/207/10971/4303/1027/7295/4287/114907/1026/84676/4088/10000/3630/4087/56729/208/23411 21 Mumps_virus R-HSA-6783589 Interleukin-6 family signaling 12/1098 24/10654 1.1263368547093594e-6 5.537822868987684e-6 3.180466640699779e-6 9021/6774/6772/867/3717/3716/3570/5008/7297/5781/3569/3572 12 Mumps_virus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 12/1098 24/10654 1.1263368547093594e-6 5.537822868987684e-6 3.180466640699779e-6 596/2309/5747/207/5594/1027/10000/208/7514/1385/1956/5595 12 Mumps_virus R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 10/1098 17/10654 1.2823203304975523e-6 6.279821697574969e-6 3.6066092923500954e-6 23643/8737/355/841/7099/929/8772/353376/8743/148022 10 Mumps_virus R-HSA-9614399 Regulation of localization of FOXO transcription factors 8/1098 11/10654 1.541961720422872e-6 7.5216164236375525e-6 4.319793298822469e-6 2308/2309/7532/207/10971/4303/10000/208 8 Mumps_virus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 22/1098 72/10654 1.8029521907997587e-6 8.72600689219102e-6 5.011495398769068e-6 11065/246184/7321/991/8697/8881/7316/51433/5715/6502/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/7314/996 22 Mumps_virus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 22/1098 72/10654 1.8029521907997587e-6 8.72600689219102e-6 5.011495398769068e-6 11065/246184/7321/8697/898/8881/7316/890/51433/5715/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/7314/996 22 Mumps_virus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 12/1098 25/10654 1.9634140142282723e-6 9.465641881824238e-6 5.436280457171051e-6 1849/5594/5528/5519/1432/1385/5518/6197/5600/5595/5515/5516 12 Mumps_virus R-HSA-445717 Aquaporin-mediated transport 18/1098 52/10654 2.108265347025095e-6 1.0124576608387956e-5 5.81471797057921e-6 2788/54331/59345/10681/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 18 Mumps_virus R-HSA-5654738 Signaling by FGFR2 22/1098 73/10654 2.3329419765016853e-6 1.1160289995697252e-5 6.40954593015704e-6 5295/4893/5290/5335/5430/5594/10817/7316/6714/867/5437/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 22 Mumps_virus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 24/1098 84/10654 2.364834140963972e-6 1.1269344233286005e-5 6.47217764895403e-6 9318/7336/8450/54778/7316/9978/64708/10980/10920/142/10987/7329/6233/2873/2968/7311/60/8533/6117/7334/50813/7314/51138/8451 24 Mumps_virus R-HSA-187687 Signalling to ERKs 14/1098 34/10654 2.6927921329073e-6 1.2783024722881778e-5 7.3415103119392415e-6 4893/5594/6714/1432/4914/5603/2885/1398/3845/5600/3265/1399/6300/5595 14 Mumps_virus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 20/1098 63/10654 2.7275552831443074e-6 1.2898629755022125e-5 7.407904264385504e-6 11065/246184/7321/8697/8881/7316/51433/5715/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/7314/996 20 Mumps_virus R-HSA-198753 ERK/MAPK targets 11/1098 22/10654 3.1982313946263956e-6 1.500988143159888e-5 8.620432307685181e-6 1849/5594/5528/5519/1432/5518/6197/5600/5595/5515/5516 11 Mumps_virus R-HSA-9613829 Chaperone Mediated Autophagy 11/1098 22/10654 3.1982313946263956e-6 1.500988143159888e-5 8.620432307685181e-6 2670/1080/7316/3920/3320/6233/3326/7311/7431/3312/7314 11 Mumps_virus R-HSA-109704 PI3K Cascade 16/1098 44/10654 3.7014002819136986e-6 1.7305792261475745e-5 9.939013269408783e-6 5295/54106/5170/5290/3667/5291/2322/57761/5140/2261/208/2885/8660/5296/117145/5781 16 Mumps_virus R-HSA-3858494 Beta-catenin independent WNT signaling 34/1098 146/10654 3.7502850106987886e-6 1.7468432812991724e-5 1.0032420527235386e-5 2788/57154/1173/54331/6885/1499/59345/10681/51764/94235/64750/7316/55970/5216/2792/5715/2793/2785/2783/2784/2782/2786/6233/163/7311/387/4343/3845/801/2791/7314/5879/2790/2787 34 Mumps_virus R-HSA-210990 PECAM1 interactions 8/1098 12/10654 4.206385813105053e-6 1.9519520683285246e-5 1.1210395464849264e-5 5777/5335/6714/4067/2534/7525/3932/5781 8 Mumps_virus R-HSA-1296065 Inwardly rectifying K+ channels 13/1098 31/10654 4.814941770928411e-6 2.217737120513123e-5 1.2736844598503643e-5 2788/54331/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 13 Mumps_virus R-HSA-5654733 Negative regulation of FGFR4 signaling 13/1098 31/10654 4.814941770928411e-6 2.217737120513123e-5 1.2736844598503643e-5 5594/7316/6714/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 13 Mumps_virus R-HSA-163200 Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 30/1098 123/10654 5.136271474434307e-6 2.356977909934854e-5 1.353652833028301e-5 51300/9377/4722/4723/4702/7388/4719/55863/4704/2109/51295/4729/7386/6389/6341/7385/4728/4725/27089/2108/4726/7384/51204/6834/4698/1340/1327/4697/4720/51079 30 Mumps_virus R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 19/1098 61/10654 6.612514060815312e-6 3.023212148099694e-5 1.7362825811268798e-5 25/5747/4690/4771/5594/4644/6850/3320/998/695/2885/1398/7410/10096/3326/7409/60/5879/5595 19 Mumps_virus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 21/1098 72/10654 7.010335581976819e-6 3.193310950760764e-5 1.833973240486196e-5 11065/246184/7321/991/8697/8881/7316/890/51433/5715/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 21 Mumps_virus R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 13/1098 32/10654 7.348634885630055e-6 3.335149678862871e-5 1.9154336543998144e-5 5295/5777/4690/5336/6850/4067/2534/695/2885/7409/5293/118788/801 13 Mumps_virus R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 9/1098 16/10654 7.424722352390112e-6 3.357383574675675e-5 1.9282029620498338e-5 5295/5170/5290/5291/6850/4067/2534/2885/5296 9 Mumps_virus R-HSA-9612973 Autophagy 29/1098 119/10654 7.47829599559767e-6 3.369312268562005e-5 1.9350538155115888e-5 2670/7249/1080/10533/64419/7416/192111/7316/8678/6714/64223/56993/3920/3320/6009/55054/6233/3326/2475/9804/7311/54543/55626/7431/3312/5564/57521/7248/7314 29 Mumps_virus R-HSA-422356 Regulation of insulin secretion 22/1098 78/10654 7.787032772195155e-6 3.4957005814310856e-5 2.0076407910007342e-5 2788/54331/59345/10681/51764/94235/4082/55970/2778/2792/2793/2785/2783/2784/2782/3630/2786/948/6844/2791/2790/2787 22 Mumps_virus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 20/1098 67/10654 7.840495446239933e-6 3.5069941725239266e-5 2.0141268940369353e-5 11065/246184/7321/991/8697/8881/7316/51433/5715/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 20 Mumps_virus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 21/1098 73/10654 8.899282999572509e-6 3.966263178586453e-5 2.277892960132911e-5 11065/246184/7321/991/8697/8881/7316/890/51433/5715/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 21 Mumps_virus R-HSA-167044 Signalling to RAS 10/1098 20/10654 9.110009387871464e-6 4.0311791541331226e-5 2.3151753181207184e-5 4893/6714/1432/4914/5603/2885/3845/5600/3265/6300 10 Mumps_virus R-HSA-8876384 Listeria monocytogenes entry into host cells 10/1098 20/10654 9.110009387871464e-6 4.0311791541331226e-5 2.3151753181207184e-5 1499/7316/4233/6714/867/9146/6233/2885/7311/7314 10 Mumps_virus R-HSA-9006936 Signaling by TGF-beta family members 26/1098 102/10654 9.237984775510529e-6 4.0732609027962795e-5 2.339343588029638e-5 57154/5590/892/7027/7321/6497/10273/4738/64750/7323/54778/7316/6667/4609/23327/867/4088/142/9040/4087/6233/7514/1025/7311/387/7314 26 Mumps_virus R-HSA-447115 Interleukin-12 family signaling 18/1098 57/10654 9.293754561555812e-6 4.083319823321862e-5 2.3451205985859388e-5 3592/3593/6775/3595/4478/3313/6774/6772/149233/3717/3458/998/3716/3594/51561/7297/3586/3572 18 Mumps_virus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 16/1098 47/10654 9.9042692963681e-6 4.278868870553449e-5 2.4574277698433648e-5 4893/5594/6714/3717/2244/1445/5894/2266/2243/60/3845/3265/369/801/5245/5595 16 Mumps_virus R-HSA-6802949 Signaling by RAS mutants 16/1098 47/10654 9.9042692963681e-6 4.278868870553449e-5 2.4574277698433648e-5 4893/5594/6714/3717/2244/1445/5894/2266/2243/60/3845/3265/369/801/5245/5595 16 Mumps_virus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 16/1098 47/10654 9.9042692963681e-6 4.278868870553449e-5 2.4574277698433648e-5 4893/5594/6714/3717/2244/1445/5894/2266/2243/60/3845/3265/369/801/5245/5595 16 Mumps_virus R-HSA-9649948 Signaling downstream of RAS mutants 16/1098 47/10654 9.9042692963681e-6 4.278868870553449e-5 2.4574277698433648e-5 4893/5594/6714/3717/2244/1445/5894/2266/2243/60/3845/3265/369/801/5245/5595 16 Mumps_virus R-HSA-171007 p38MAPK events 8/1098 13/10654 9.94603902114119e-6 4.278868870553449e-5 2.4574277698433648e-5 4893/6714/1432/5603/3845/5600/3265/6300 8 Mumps_virus R-HSA-202670 ERKs are inactivated 8/1098 13/10654 9.94603902114119e-6 4.278868870553449e-5 2.4574277698433648e-5 1849/5594/5528/5519/5518/5595/5515/5516 8 Mumps_virus R-HSA-8856828 Clathrin-mediated endocytosis 33/1098 146/10654 1.0219375468823426e-5 4.3812478221011165e-5 2.516225757393785e-5 9318/1173/23396/4738/1601/1785/1080/338/7316/64708/26052/10980/867/9146/10920/10987/29979/6233/2885/2873/10096/6844/163/7311/3575/1759/1956/60/8533/3312/50813/7314/51138 33 Mumps_virus R-HSA-6807070 PTEN Regulation 32/1098 140/10654 1.0855993843244733e-5 4.6330435319361394e-5 2.660836351547369e-5 3725/5468/1822/23186/10273/207/6045/5594/7316/4734/64223/10014/5715/10000/23512/5728/6009/6615/7157/23028/5371/208/6233/2475/7311/1386/4343/648/57521/23608/7314/5595 32 Mumps_virus R-HSA-5654726 Negative regulation of FGFR1 signaling 13/1098 33/10654 1.098845130211047e-5 4.6330435319361394e-5 2.660836351547369e-5 5594/7316/6714/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 13 Mumps_virus R-HSA-450341 Activation of the AP-1 family of transcription factors 7/1098 10/10654 1.0993662618153551e-5 4.6330435319361394e-5 2.660836351547369e-5 3725/5594/1432/1386/5599/5600/5595 7 Mumps_virus R-HSA-74749 Signal attenuation 7/1098 10/10654 1.0993662618153551e-5 4.6330435319361394e-5 2.660836351547369e-5 3643/3667/5594/3630/2885/8660/5595 7 Mumps_virus R-HSA-8853334 Signaling by FGFR3 fusions in cancer 7/1098 10/10654 1.0993662618153551e-5 4.6330435319361394e-5 2.660836351547369e-5 5295/4893/5290/2261/2885/3845/3265 7 Mumps_virus R-HSA-73893 DNA Damage Bypass 16/1098 48/10654 1.3449587001971268e-5 5.648826540827933e-5 3.244217953017869e-5 7320/7706/8450/7316/9978/10459/25898/7398/9246/57599/6233/7311/7318/6117/7314/8451 16 Mumps_virus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 21/1098 75/10654 1.4112685984806756e-5 5.907303356478233e-5 3.392665620814143e-5 11065/246184/7321/991/8697/8881/7316/890/51433/5715/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 21 Mumps_virus R-HSA-9034015 Signaling by NTRK3 (TRKC) 9/1098 17/10654 1.433492462701926e-5 5.9801251221807624e-5 3.434488409663307e-5 5295/4893/5290/3667/5335/6714/2885/3845/3265 9 Mumps_virus R-HSA-8854691 Interleukin-20 family signaling 11/1098 25/10654 1.5086405427832285e-5 6.272502122511477e-5 3.602405534869172e-5 6775/6776/6774/3718/6772/3717/3716/6777/6773/7297/5781 11 Mumps_virus R-HSA-190236 Signaling by FGFR 23/1098 87/10654 1.5781440345146448e-5 6.520883998967287e-5 3.745055505969914e-5 5295/4893/5290/5335/5430/5594/10817/7316/6714/2261/867/5437/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 23 Mumps_virus R-HSA-5218921 VEGFR2 mediated cell proliferation 10/1098 21/10654 1.578906537280215e-5 6.520883998967287e-5 3.745055505969914e-5 5170/5590/4893/5335/7422/5921/6714/3845/3265/801 10 Mumps_virus R-HSA-5654727 Negative regulation of FGFR2 signaling 13/1098 34/10654 1.6123859359236154e-5 6.637030480429766e-5 3.8117604220470865e-5 5594/7316/6714/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 13 Mumps_virus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 21/1098 76/10654 1.763581524063735e-5 7.235355987797905e-5 4.155389021495591e-5 11065/246184/7321/991/8697/8881/7316/890/51433/5715/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 21 Mumps_virus R-HSA-69618 Mitotic Spindle Checkpoint 27/1098 112/10654 1.8886294900909785e-5 7.722811677302715e-5 4.435343183260384e-5 5905/11065/246184/5525/7321/991/5526/8697/8881/5528/51433/5519/1062/5529/51529/7324/64682/29945/10393/5527/51434/7514/5518/29882/996/5515/5516 27 Mumps_virus R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 26/1098 106/10654 1.935515351642484e-5 7.888498423306046e-5 4.530499922819666e-5 9318/1173/4738/1601/1080/338/7316/64708/10980/867/9146/10920/10987/29979/6233/2885/2873/6844/163/7311/3575/1956/8533/50813/7314/51138 26 Mumps_virus R-HSA-114452 Activation of BH3-only proteins 12/1098 30/10654 2.0005134166580626e-5 8.100118049801763e-5 4.652036703339699e-5 596/10018/7027/572/7532/207/10971/7533/10000/7157/208/5599 12 Mumps_virus R-HSA-6804758 Regulation of TP53 Activity through Acetylation 12/1098 30/10654 2.0005134166580626e-5 8.100118049801763e-5 4.652036703339699e-5 23774/64769/7862/207/84289/27154/10000/7994/7157/5371/208/5300 12 Mumps_virus R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 8/1098 14/10654 2.1108093985734013e-5 8.491210535170273e-5 4.8766478244552955e-5 4893/5921/5753/1398/387/3845/3265/5879 8 Mumps_virus R-HSA-8983432 Interleukin-15 signaling 8/1098 14/10654 2.1108093985734013e-5 8.491210535170273e-5 4.8766478244552955e-5 3561/6776/3560/6774/3718/2885/3716/6777 8 Mumps_virus R-HSA-69239 Synthesis of DNA 28/1098 119/10654 2.1567093207976987e-5 8.647776208635433e-5 4.966566175640417e-5 8454/11065/246184/7321/8697/6500/898/8881/7316/5422/9978/890/51433/5715/6502/51529/7324/64682/29945/10393/6233/51434/51343/7311/6117/29882/7314/996 28 Mumps_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 22/1098 83/10654 2.2967746636786386e-5 9.179689704186558e-5 5.2720532178158234e-5 8454/1147/8945/4893/4790/6885/5966/6500/8517/7316/5970/4792/8915/5715/23291/6233/7311/3845/3265/3551/801/7314 22 Mumps_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 11/1098 26/10654 2.3725759551799495e-5 9.452159512758706e-5 5.428537301410209e-5 57154/10273/64750/7316/23327/4088/4087/6233/7514/7311/7314 11 Mumps_virus R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 9/1098 18/10654 2.6051223002800926e-5 1.0345341442458445e-4 5.941507000638809e-5 4893/5594/2885/1385/1956/6197/3845/3265/5595 9 Mumps_virus R-HSA-8943724 Regulation of PTEN gene transcription 18/1098 61/10654 2.6348432865567896e-5 1.0429938760523522e-4 5.990092691146427e-5 3725/5468/1822/23186/6045/5594/64223/10014/23512/6009/6615/7157/23028/2475/1386/648/57521/5595 18 Mumps_virus R-HSA-5655291 Signaling by FGFR4 in disease 7/1098 11/10654 2.753413918918219e-5 1.0864585495349278e-4 6.239717764628617e-5 5295/4893/5290/5335/2885/3845/3265 7 Mumps_virus R-HSA-69306 DNA Replication 29/1098 127/10654 2.8281008091096812e-5 1.1123863182498078e-4 6.388625386660468e-5 8454/11065/246184/7321/8317/8697/6500/898/8881/7316/5422/9978/890/51433/5715/6502/51529/7324/64682/29945/10393/6233/51434/51343/7311/6117/29882/7314/996 29 Mumps_virus R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 12/1098 31/10654 2.9598939890150508e-5 1.1605407127815342e-4 6.66518433235901e-5 857/1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 12 Mumps_virus R-HSA-8878166 Transcriptional regulation by RUNX2 28/1098 121/10654 2.9885392271819397e-5 1.1680757421067582e-4 6.708459297941198e-5 8454/57154/25/10273/207/5594/6500/7316/9978/865/11059/1026/10413/6772/6714/2099/5715/2932/6502/10000/55294/861/208/6233/7525/7311/7314/5595 28 Mumps_virus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 13/1098 36/10654 3.2985075780641416e-5 1.2851732356042363e-4 7.380970283917114e-5 4893/5594/6714/2244/1445/5894/2266/2243/60/3845/3265/369/5595 13 Mumps_virus R-HSA-354192 Integrin alphaIIb beta3 signaling 11/1098 27/10654 3.632884820980228e-5 1.406607591623282e-4 8.078388615074456e-5 5170/5747/207/6850/6714/2244/1445/2885/1398/2266/2243 11 Mumps_virus R-HSA-9006921 Integrin signaling 11/1098 27/10654 3.632884820980228e-5 1.406607591623282e-4 8.078388615074456e-5 5170/5747/207/6850/6714/2244/1445/2885/1398/2266/2243 11 Mumps_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 21/1098 80/10654 4.1004142541196825e-5 1.5637716027658174e-4 8.981008482814602e-5 5335/2316/7706/7316/4734/6772/23586/6059/3661/7324/9246/51191/6233/3716/7311/7318/5610/5300/7334/7314/5595 21 Mumps_virus R-HSA-416482 G alpha (12/13) signalling events 21/1098 80/10654 4.1004142541196825e-5 1.5637716027658174e-4 8.981008482814602e-5 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/695/2786/7410/7409/387/2791/2790/2787 21 Mumps_virus R-HSA-111447 Activation of BAD and translocation to mitochondria 8/1098 15/10654 4.114524152555742e-5 1.5637716027658174e-4 8.981008482814602e-5 596/572/7532/207/10971/7533/10000/208 8 Mumps_virus R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 8/1098 15/10654 4.114524152555742e-5 1.5637716027658174e-4 8.981008482814602e-5 6737/29110/7316/22954/3661/6233/7311/7314 8 Mumps_virus R-HSA-844456 The NLRP3 inflammasome 8/1098 15/10654 4.114524152555742e-5 1.5637716027658174e-4 8.981008482814602e-5 834/351/4790/10910/7295/5970/3326/114548 8 Mumps_virus R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 8/1098 15/10654 4.114524152555742e-5 1.5637716027658174e-4 8.981008482814602e-5 7316/4233/867/9146/6233/2885/7311/7314 8 Mumps_virus R-HSA-112409 RAF-independent MAPK1/3 activation 10/1098 23/10654 4.222068290054368e-5 1.5997378016444533e-4 9.187568530747637e-5 1849/5594/3717/3716/3570/7297/5781/3569/3572/5595 10 Mumps_virus R-HSA-1251985 Nuclear signaling by ERBB4 12/1098 32/10654 4.294912289286277e-5 1.6174456919227043e-4 9.289267981307067e-5 2670/23118/51741/23385/348/6776/10413/6714/2099/3084/6285/6387 12 Mumps_virus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 12/1098 32/10654 4.294912289286277e-5 1.6174456919227043e-4 9.289267981307067e-5 892/7027/54778/7316/6667/4609/4088/4087/6233/1025/7311/7314 12 Mumps_virus R-HSA-5696398 Nucleotide Excision Repair 26/1098 111/10654 4.561133214612204e-5 1.7124981978498547e-4 9.835170823214834e-5 9318/5430/7336/8450/54778/7316/9978/64708/10980/5437/10920/142/10987/7329/6233/2873/2968/7311/60/8533/6117/7334/50813/7314/51138/8451 26 Mumps_virus R-HSA-2559585 Oncogene Induced Senescence 12/1098 33/10654 6.121236380186408e-5 2.2913026812842777e-4 1.315934422962637e-4 7027/5594/7316/6667/1031/7157/6233/7311/4343/7314/5595/4193 12 Mumps_virus R-HSA-5696395 Formation of Incision Complex in GG-NER 14/1098 43/10654 6.233125649363546e-5 2.3261574336028417e-4 1.3359521049365118e-4 7336/8450/54778/7316/9978/142/7329/6233/2968/7311/6117/7334/7314/8451 14 Mumps_virus R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 10/1098 24/10654 6.572667839675547e-5 2.4455061421495506e-4 1.4044961149425227e-4 5590/5594/6280/6279/1432/5300/5600/1536/5879/5595 10 Mumps_virus R-HSA-6802957 Oncogenic MAPK signaling 19/1098 71/10654 7.092103917268885e-5 2.630873279489865e-4 1.510955640741811e-4 4893/10018/55750/5594/10533/6714/3717/2244/1445/5894/2266/2243/60/3845/3265/369/801/5245/5595 19 Mumps_virus R-HSA-1632852 Macroautophagy 23/1098 95/10654 7.158856593309986e-5 2.6477084534659915e-4 1.5206243698594036e-4 7249/10533/64419/7416/192111/7316/8678/6714/64223/56993/6009/55054/6233/2475/9804/7311/54543/55626/3312/5564/57521/7248/7314 23 Mumps_virus R-HSA-8949664 Processing of SMDT1 8/1098 16/10654 7.48657606987247e-5 2.760674925765473e-4 1.585502952140912e-4 10730/11331/6687/30968/221154/10367/10939/5245 8 Mumps_virus R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 13/1098 39/10654 8.637706202746794e-5 3.1569669572871023e-4 1.8131002617782435e-4 26224/898/10517/6774/26272/26270/55294/26190/7157/6468/54461/26234/84261 13 Mumps_virus R-HSA-977444 GABA B receptor activation 13/1098 39/10654 8.637706202746794e-5 3.1569669572871023e-4 1.8131002617782435e-4 2788/54331/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 13 Mumps_virus R-HSA-991365 Activation of GABAB receptors 13/1098 39/10654 8.637706202746794e-5 3.1569669572871023e-4 1.8131002617782435e-4 2788/54331/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 13 Mumps_virus R-HSA-1169408 ISG15 antiviral mechanism 19/1098 72/10654 8.718510332114703e-5 3.167810645598275e-4 1.8193279779316374e-4 5335/7706/7316/4734/6772/23586/3661/7324/9246/51191/6233/3716/7311/7318/5610/5300/7334/7314/5595 19 Mumps_virus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 19/1098 72/10654 8.718510332114703e-5 3.167810645598275e-4 1.8193279779316374e-4 6517/7532/207/10971/57186/7533/4644/7846/9847/208/6844/9882/4012/10383/60/5564/801/5879/57148 19 Mumps_virus R-HSA-373752 Netrin-1 signaling 15/1098 50/10654 9.934491316761175e-5 3.5937090380731894e-4 2.063928728378129e-4 5335/5747/4690/6478/6477/6714/1432/2534/5603/998/5599/5600/6300/5781/5879 15 Mumps_virus R-HSA-5654708 Downstream signaling of activated FGFR3 10/1098 25/10654 9.948686037603745e-5 3.5937090380731894e-4 2.063928728378129e-4 5295/4893/5290/5335/10817/2261/2885/3845/3265/5781 10 Mumps_virus R-HSA-453279 Mitotic G1-G1/S phases 31/1098 149/10654 1.0100820645119214e-4 3.63805720328567e-4 2.0893986401776592e-4 8454/25/7027/8317/207/1027/6500/898/7316/5422/5753/890/1026/6714/4609/1031/5715/5519/4067/3717/6502/10000/208/6233/7311/5518/6117/1859/7314/5515/5516 31 Mumps_virus R-HSA-1169091 Activation of NF-kappaB in B cells 18/1098 67/10654 1.033491593688086e-4 3.700855735779013e-4 2.1254649143083245e-4 8454/1147/8945/4790/6885/5966/6500/8517/7316/5970/4792/8915/5715/23291/6233/7311/3551/7314 18 Mumps_virus R-HSA-6802952 Signaling by BRAF and RAF fusions 18/1098 67/10654 1.033491593688086e-4 3.700855735779013e-4 2.1254649143083245e-4 4893/10018/55750/5594/10533/6714/3717/2244/1445/5894/2266/2243/60/3845/3265/369/801/5595 18 Mumps_virus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 20/1098 79/10654 1.0768704097202833e-4 3.845079071018533e-4 2.20829484899412e-4 9318/5430/8450/7316/9978/64708/10980/5437/10920/10987/6233/2873/2968/7311/8533/6117/50813/7314/51138/8451 20 Mumps_virus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 11/1098 30/10654 1.1377200813825062e-4 4.050675806991164e-4 2.3263725802013743e-4 7320/8450/7316/9978/7398/57599/6233/7311/6117/7314/8451 11 Mumps_virus R-HSA-5674135 MAP2K and MAPK activation 13/1098 40/10654 1.1602146622927499e-4 4.1189282710049196e-4 2.3655711407326167e-4 4893/5594/6714/2244/1445/5894/2266/2243/60/3845/3265/369/5595 13 Mumps_virus R-HSA-69620 Cell Cycle Checkpoints 51/1098 293/10654 1.1718298330162776e-4 4.148277608877623e-4 2.3824269687789588e-4 5905/11065/246184/5525/7321/991/5526/7532/8317/10971/8697/1027/898/7533/545/472/7336/8881/29086/5528/7316/890/1026/51433/5715/5519/1062/5529/7157/51529/7324/64682/29945/10393/8924/6233/5527/51434/7514/7158/7311/5518/6117/29882/7334/51230/7314/996/4193/5515/5516 51 Mumps_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 9/1098 21/10654 1.1823652304799533e-4 4.161791251604154e-4 2.390188085539619e-4 4893/4790/5970/4067/2534/5894/30835/3845/3265 9 Mumps_virus R-HSA-6807004 Negative regulation of MET activity 9/1098 21/10654 1.1823652304799533e-4 4.161791251604154e-4 2.390188085539619e-4 9101/7316/4233/867/9146/6233/2885/7311/7314 9 Mumps_virus R-HSA-1679131 Trafficking and processing of endosomal TLR 7/1098 13/10654 1.1881444129266413e-4 4.170285913926653e-4 2.395066715784731e-4 54106/10695/7184/7098/51311/81622/51284 7 Mumps_virus R-HSA-195721 Signaling by WNT 56/1098 331/10654 1.2184915484959254e-4 4.2647204197357393e-4 2.4493020719097404e-4 2788/8454/57154/8945/1173/857/54331/6885/1499/5525/59345/5526/207/6500/10681/51764/9101/94235/64750/8452/5528/7316/9978/55970/5216/2792/4609/5715/5519/2932/2793/2785/2783/2784/5529/2782/2786/208/6233/5527/7514/163/7311/5518/387/4343/25776/3845/801/2791/7314/5879/2790/5515/2787/5516 56 Mumps_virus R-HSA-877300 Interferon gamma signaling 22/1098 92/10654 1.241621518691615e-4 4.333433976503974e-4 2.48876544591707e-4 3665/3460/5777/6737/960/9021/85363/9830/3383/7706/3113/6772/8651/3659/3459/3717/3458/3661/5371/3716/81603/5781 22 Mumps_virus R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 8/1098 17/10654 1.2867094831801849e-4 4.478182723764744e-4 2.571897133736857e-4 2308/857/2309/4303/1027/1026/4088/4087 8 Mumps_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 20/1098 82/10654 1.868083747616469e-4 6.483349477021863e-4 3.723498786344488e-4 8454/8945/1499/5525/5526/6500/5528/7316/9978/5715/5519/2932/5529/6233/5527/7311/5518/7314/5515/5516 20 Mumps_virus R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 8/1098 18/10654 2.107667285701922e-4 7.294412756940451e-4 4.1893063367671253e-4 5295/5290/6776/6774/6772/2885/6777/7750 8 Mumps_virus R-HSA-2467813 Separation of Sister Chromatids 36/1098 190/10654 2.1583018829623204e-4 7.448846888552409e-4 4.278000506912561e-4 5905/11065/246184/5525/7321/991/5526/8697/8881/5528/7316/51433/5715/5519/1062/7846/8243/9126/5529/51529/7324/64682/29945/10393/6233/5527/51434/7514/7311/5518/10383/29882/7314/996/5515/5516 36 Mumps_virus R-HSA-5689880 Ub-specific processing proteases 40/1098 220/10654 2.459679248832398e-4 8.46539608139817e-4 4.8618221409669636e-4 6885/90865/991/8737/9817/4303/91833/6478/1080/330/9101/8517/64750/7416/7316/890/7417/4792/8678/4609/23586/5715/329/6502/4088/9146/64135/5728/10454/7157/4087/63891/7189/57599/6233/9804/7311/1540/7314/4193 40 Mumps_virus R-HSA-5655302 Signaling by FGFR1 in disease 12/1098 38/10654 2.8697758302333545e-4 9.849452226202565e-4 5.656709319835976e-4 5295/4893/5290/5335/6776/6774/6772/2885/3845/6777/3265/7750 12 Mumps_virus R-HSA-202733 Cell surface interactions at the vascular wall 28/1098 137/10654 2.938540150233972e-4 0.0010057600127458264 5.77625222901473e-4 5295/5777/4893/857/5290/5335/960/5291/483/6401/3684/7010/2888/338/3688/6714/4067/54210/682/2534/2885/7525/3932/5296/3687/3845/3265/5781 28 Mumps_virus R-HSA-2871809 FCERI mediated Ca+2 mobilization 11/1098 33/10654 3.015159545111479e-4 0.0010291412331661493 5.910534587488358e-4 5335/5336/6850/4067/695/2885/7410/7006/7409/3702/801 11 Mumps_virus R-HSA-6799198 Complex I biogenesis 15/1098 55/10654 3.207437145009173e-4 0.0010917622589742763 6.270177877461543e-4 51300/4722/4723/4702/4719/55863/4704/51295/4729/4728/4725/4726/4698/4720/51079 15 Mumps_virus R-HSA-376172 DSCAM interactions 6/1098 11/10654 3.458383432681426e-4 0.0011643850742098605 6.687263159303904e-4 1432/5603/5599/5600/6300/5879 6 Mumps_virus R-HSA-8875555 MET activates RAP1 and RAC1 6/1098 11/10654 3.458383432681426e-4 0.0011643850742098605 6.687263159303904e-4 85440/4233/2885/1398/1399/5879 6 Mumps_virus R-HSA-9020956 Interleukin-27 signaling 6/1098 11/10654 3.458383432681426e-4 0.0011643850742098605 6.687263159303904e-4 6774/6772/3717/3716/7297/3572 6 Mumps_virus R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 6/1098 11/10654 3.458383432681426e-4 0.0011643850742098605 6.687263159303904e-4 4893/10817/2885/3845/3265/5781 6 Mumps_virus R-HSA-76009 Platelet Aggregation (Plug Formation) 12/1098 39/10654 3.7613337013261045e-4 0.0012629518850794156 7.253349257157173e-4 5170/5747/207/6850/6714/4352/2244/1445/2885/1398/2266/2243 12 Mumps_virus R-HSA-1236975 Antigen processing-Cross presentation 22/1098 99/10654 3.809866425349976e-4 0.0012757904056780055 7.327083082607637e-4 23643/1147/6890/10333/7099/8517/4615/7316/7096/5715/929/114609/695/6233/948/4012/7311/7097/3551/1536/7314/4360 22 Mumps_virus R-HSA-4791275 Signaling by WNT in cancer 11/1098 34/10654 4.046815402131634e-4 0.001351483634296791 7.7618022750489e-4 1499/5525/5526/5528/5519/2932/5529/5527/5518/5515/5516 11 Mumps_virus R-HSA-5205647 Mitophagy 10/1098 29/10654 4.151446015128238e-4 0.001378992389475573 7.919789773463212e-4 7416/192111/7316/6714/56993/6233/9804/7311/54543/7314 10 Mumps_virus R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 10/1098 29/10654 4.151446015128238e-4 0.001378992389475573 7.919789773463212e-4 2308/2309/4303/4287/114907/84676/4088/3630/4087/56729 10 Mumps_virus R-HSA-165159 mTOR signalling 12/1098 40/10654 4.876099003768939e-4 0.001615370766221849 9.277351327182109e-4 207/84335/7249/6198/64223/6009/208/2475/1978/5564/57521/7248 12 Mumps_virus R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 10/1098 30/10654 5.658308982001089e-4 0.0018695052876531598 0.0010736889464793647 5170/4893/5594/1742/1385/6197/3845/3265/801/5595 10 Mumps_virus R-HSA-1963640 GRB2 events in ERBB2 signaling 7/1098 16/10654 5.995033279709949e-4 0.0019546963772527964 0.0011226156501617523 4893/2064/3084/2885/1956/3845/3265 7 Mumps_virus R-HSA-1963642 PI3K events in ERBB2 signaling 7/1098 16/10654 5.995033279709949e-4 0.0019546963772527964 0.0011226156501617523 5295/5290/2065/2064/3084/2885/1956 7 Mumps_virus R-HSA-205043 NRIF signals cell death from the nucleus 7/1098 16/10654 5.995033279709949e-4 0.0019546963772527964 0.0011226156501617523 23385/7316/7189/6233/7311/5599/7314 7 Mumps_virus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 7/1098 16/10654 5.995033279709949e-4 0.0019546963772527964 0.0011226156501617523 57154/5590/7316/6233/7311/387/7314 7 Mumps_virus R-HSA-391160 Signal regulatory protein family interactions 7/1098 16/10654 5.995033279709949e-4 0.0019546963772527964 0.0011226156501617523 5777/5747/653509/6714/2885/2185/5781 7 Mumps_virus R-HSA-8853659 RET signaling 12/1098 41/10654 6.256381883462754e-4 0.0020345556833622973 0.001168480219152044 5295/2674/5290/5335/5291/6714/8503/2885/8660/5293/5296/5781 12 Mumps_virus R-HSA-264870 Caspase-mediated cleavage of cytoskeletal proteins 6/1098 12/10654 6.31483692620595e-4 0.002034979824366627 0.0011687238106043414 2934/841/5339/836/6709/7431 6 Mumps_virus R-HSA-5689877 Josephin domain DUBs 6/1098 12/10654 6.31483692620595e-4 0.002034979824366627 0.0011687238106043414 4287/7316/9929/6233/7311/7314 6 Mumps_virus R-HSA-9634600 Regulation of glycolysis by fructose 2,6-bisphosphate metabolism 6/1098 12/10654 6.31483692620595e-4 0.002034979824366627 0.0011687238106043414 5528/5519/5208/5518/5515/5516 6 Mumps_virus R-HSA-1236974 ER-Phagosome pathway 19/1098 83/10654 6.323383635037542e-4 0.002034979824366627 0.0011687238106043414 23643/1147/6890/10333/7099/8517/4615/7316/7096/5715/929/114609/695/6233/948/7311/7097/3551/7314 19 Mumps_virus R-HSA-68882 Mitotic Anaphase 36/1098 201/10654 6.586927297976172e-4 0.0021143012751793982 0.001214279480074146 5905/11065/246184/5525/7321/991/5526/8697/8881/5528/7316/51433/5715/5519/1062/7846/8243/9126/5529/51529/7324/64682/29945/10393/6233/5527/51434/7514/7311/5518/10383/29882/7314/996/5515/5516 36 Mumps_virus R-HSA-9020591 Interleukin-12 signaling 13/1098 47/10654 6.844627588005665e-4 0.0021913420107335965 0.0012585252956594125 3592/3593/6775/3595/4478/3313/3717/3458/998/3716/3594/7297/3586 13 Mumps_virus R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 11/1098 36/10654 7.00741492827937e-4 0.0022376770866335415 0.0012851363243398955 25/5747/4690/5594/998/695/2885/10096/60/5879/5595 11 Mumps_virus R-HSA-2555396 Mitotic Metaphase and Anaphase 36/1098 202/10654 7.241952120001778e-4 0.00230502693189672 0.0013238164954438494 5905/11065/246184/5525/7321/991/5526/8697/8881/5528/7316/51433/5715/5519/1062/7846/8243/9126/5529/51529/7324/64682/29945/10393/6233/5527/51434/7514/7311/5518/10383/29882/7314/996/5515/5516 36 Mumps_virus R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 15/1098 59/10654 7.255532715413404e-4 0.00230502693189672 0.0013238164954438494 7319/7321/7320/7336/5591/7323/7316/8915/7322/118424/7324/6233/7311/7334/7314 15 Mumps_virus R-HSA-193704 p75 NTR receptor-mediated signalling 21/1098 97/10654 7.391309171127065e-4 0.002342156537858423 0.0013451406648759985 4790/10018/572/8767/23385/4615/7316/5970/4792/836/3654/7189/6233/7410/7409/7311/387/5599/3551/7314/5879 21 Mumps_virus R-HSA-3928662 EPHB-mediated forward signaling 12/1098 42/10654 7.949739573052685e-4 0.002512685543625581 0.0014430783972566102 5747/5921/6714/4067/2534/998/7525/10096/387/60/3265/5879 12 Mumps_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 19/1098 85/10654 8.627238007508484e-4 0.0027198849596190866 0.0015620765750838986 8454/7027/207/1027/6500/898/7316/5753/890/1026/4609/5715/6502/10000/208/6233/51343/7311/7314 19 Mumps_virus R-HSA-2682334 EPH-Ephrin signaling 20/1098 92/10654 9.265591961946219e-4 0.0029137229545308035 0.0016734010596515215 1173/5747/23385/4318/5921/10398/6714/4067/2534/998/7525/7410/10096/163/1759/387/60/3265/1969/5879 20 Mumps_virus R-HSA-180292 GAB1 signalosome 7/1098 17/10654 9.290859937280784e-4 0.002914272268934403 0.0016737165403335938 5295/5290/6714/1445/2885/1956/5781 7 Mumps_virus R-HSA-195258 RHO GTPase Effectors 52/1098 327/10654 9.494507040453262e-4 0.002970629854323634 0.001706083668087827 5170/5905/25/5590/1499/5525/5747/4690/991/5526/2316/7532/10971/4771/5594/1027/1080/7533/6280/30851/5528/3688/10398/5216/6279/6714/5519/1432/1062/7846/3895/5529/998/23028/695/1742/5527/2885/10096/7514/5518/10383/387/60/5300/5600/801/1536/5879/5595/5515/5516 52 Mumps_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 17/1098 73/10654 9.765222288747013e-4 0.003047634865430113 0.001750308966510137 8454/57154/10273/6500/7316/9978/865/11059/6772/2099/5715/2932/6502/55294/6233/7311/7314 17 Mumps_virus R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission 36/1098 206/10654 0.0010472122056481908 0.003260040007030423 0.0018722968818253825 2788/5170/1173/4893/54331/59345/5594/10681/51764/94235/55970/2792/6714/2793/7846/3084/2785/2783/2784/2782/2786/1742/1385/163/10383/6197/3845/3265/5564/801/2791/5879/5595/4193/2790/2787 36 Mumps_virus R-HSA-1250196 SHC1 events in ERBB2 signaling 8/1098 22/10654 0.001057744307109541 0.003260062677882391 0.0018723099020844457 4893/2065/2064/3084/2885/1956/3845/3265 8 Mumps_virus R-HSA-5205685 Pink/Parkin Mediated Mitophagy 8/1098 22/10654 0.001057744307109541 0.003260062677882391 0.0018723099020844457 7416/7316/56993/6233/9804/7311/54543/7314 8 Mumps_virus R-HSA-5655332 Signaling by FGFR3 in disease 8/1098 22/10654 0.001057744307109541 0.003260062677882391 0.0018723099020844457 5295/4893/5290/5335/2261/2885/3845/3265 8 Mumps_virus R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 8/1098 22/10654 0.001057744307109541 0.003260062677882391 0.0018723099020844457 5295/4893/5290/5335/2261/2885/3845/3265 8 Mumps_virus R-HSA-5654716 Downstream signaling of activated FGFR4 9/1098 27/10654 0.0010659526086422872 0.003276205037202918 0.0018815807358643839 5295/4893/5290/5335/10817/2885/3845/3265/5781 9 Mumps_virus R-HSA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 6/1098 13/10654 0.0010709144794731089 0.003276205037202918 0.0018815807358643839 7027/5422/5519/5518/5515/5516 6 Mumps_virus R-HSA-879415 Advanced glycosylation endproduct receptor signaling 6/1098 13/10654 0.0010709144794731089 0.003276205037202918 0.0018815807358643839 351/5594/177/3146/6285/5595 6 Mumps_virus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 11/1098 38/10654 0.001157702363108022 0.00353298824603655 0.0020290557362225123 3815/7422/51741/2064/348/1026/2099/4609/3329/7329/1956 11 Mumps_virus R-HSA-416476 G alpha (q) signalling events 37/1098 217/10654 0.001426003451970365 0.004341076847644428 0.002493154877879133 5295/2788/351/4893/5290/54331/10161/59345/5594/3358/10681/51764/2150/94235/2693/55970/2792/8503/2793/2785/2783/2784/2782/695/2786/2869/2885/1385/1956/5296/6197/3845/3265/2791/5595/2790/2787 37 Mumps_virus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 21/1098 102/10654 0.0014596075928886303 0.00443248482252209 0.002545652045388839 8454/7124/1147/8945/8744/8600/9039/6500/330/7316/9020/7133/5715/329/23291/9040/6233/7311/7187/958/7314 21 Mumps_virus R-HSA-1226099 Signaling by FGFR in disease 15/1098 63/10654 0.0015001601953216592 0.004533410931715941 0.0026036156406609545 5295/4893/5290/5335/5430/6776/6774/6772/2261/5437/2885/3845/6777/3265/7750 15 Mumps_virus R-HSA-9033241 Peroxisomal protein import 15/1098 63/10654 0.0015001601953216592 0.004533410931715941 0.0026036156406609545 1891/7321/51/10965/7323/7316/7322/1962/4843/10455/8540/6233/4358/7311/7314 15 Mumps_virus R-HSA-3928665 EPH-ephrin mediated repulsion of cells 13/1098 51/10654 0.0015702249447743918 0.004733597826217692 0.0027185864071391703 1173/23385/4318/6714/4067/2534/7525/7410/163/1759/60/1969/5879 13 Mumps_virus R-HSA-8878159 Transcriptional regulation by RUNX3 20/1098 96/10654 0.0016117699996619737 0.004847046188303848 0.0027837417469889995 57154/2309/1499/10018/64750/7316/865/1026/10413/6714/4609/5715/4088/7157/861/6233/7311/3845/7314/4193 20 Murid_herpesvirus_1 R-HSA-5663202 Diseases of signal transduction 10/32 377/10654 8.786792567521967e-8 3.0138698506600348e-5 1.84985106684673e-5 4193/2100/3066/2248/1452/324/2253/4609/1026/1385 10 Murid_herpesvirus_1 R-HSA-2219528 PI3K/AKT Signaling in Cancer 6/32 101/10654 4.638594622146173e-7 7.955189776980687e-5 4.8827311812064984e-5 4193/2100/2248/2253/1026/1385 6 Murid_herpesvirus_1 R-HSA-1257604 PIP3 activates AKT signaling 7/32 264/10654 1.0489203791535973e-5 0.0011992656334989461 7.360844765990158e-4 4193/2100/3066/2248/2253/1026/1385 7 Murid_herpesvirus_1 R-HSA-9006925 Intracellular signaling by second messengers 7/32 305/10654 2.6743136756061744e-5 0.0022932239768322944 0.0014075335134769338 4193/2100/3066/2248/2253/1026/1385 7 Murid_herpesvirus_1 R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 3/32 25/10654 5.41286175271375e-5 0.0037132231623616323 0.002279099685353158 4193/1026/1385 3 Murine_coronavirus R-HSA-9006936 Signaling by TGF-beta family members 74/365 102/10654 7.483414763234416e-88 7.670500132315277e-85 4.0646758082410094e-85 4089/4093/22938/57154/7048/1025/4086/1030/11171/60436/658/7311/23327/56288/25937/51592/9110/867/3726/8812/7050/7046/8928/92/4088/650/7040/64750/659/130399/7323/10589/1874/904/8239/54778/7316/142/892/1875/9611/905/7027/23439/9765/91/93/7321/5494/51377/3065/3624/2280/6497/6498/9612/9958/10273/56937/1024/4087/4091/6667/5933/4092/4090/4609/7314/657/6233/4221/5054/3625/9372 74 Murine_coronavirus R-HSA-170834 Signaling by TGF-beta Receptor Complex 57/365 73/10654 1.1554429308687892e-70 5.921645020702544e-68 3.1379397490962905e-68 4089/22938/57154/7048/1025/1030/11171/60436/7311/23327/56288/25937/51592/9110/867/3726/8812/7050/7046/4088/7040/64750/7323/1874/904/8239/54778/7316/142/892/1875/9611/905/7027/23439/7321/5494/51377/3065/2280/6497/6498/9612/9958/10273/56937/1024/4087/6667/5933/4092/4609/7314/6233/4221/5054/9372 57 Murine_coronavirus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 43/365 44/10654 3.499761204175723e-63 1.1957517447600387e-60 6.336409759139205e-61 4089/22938/1025/1030/60436/7311/23327/25937/51592/3726/8812/7050/4088/64750/7323/1874/904/8239/54778/7316/142/892/1875/9611/905/7027/23439/7321/5494/3065/6497/6498/9612/1024/4087/6667/5933/4092/4609/7314/6233/4221/5054 43 Murine_coronavirus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 31/365 32/10654 3.307551796617333e-45 8.475601478831916e-43 4.491307176459326e-43 4089/22938/1025/1030/60436/7311/25937/3726/8812/7050/4088/1874/904/54778/7316/892/1875/905/7027/23439/3065/1024/4087/6667/5933/4092/4609/7314/6233/4221/5054 31 Murine_coronavirus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 23/365 23/10654 1.0065825404900495e-34 2.0634942080046013e-32 1.0934665071428748e-32 4089/60436/7311/23327/51592/7050/4088/64750/7323/8239/54778/7316/142/9611/7321/5494/3065/6497/6498/9612/4087/7314/6233 23 Murine_coronavirus R-HSA-449147 Signaling by Interleukins 71/365 461/10654 6.891892871058825e-28 1.177365032139216e-25 6.238976704326935e-26 8454/6500/1147/5778/2353/2308/7311/3091/834/1052/10148/1432/3725/5777/4208/8945/867/25930/3932/4318/7076/3726/5518/6950/1386/5601/351/4088/5290/4615/7040/6935/3667/5602/2335/6885/5599/84867/5784/6597/5606/2309/7316/6175/9978/3312/26469/5657/3929/5771/5782/5783/5781/27178/6774/7157/5970/1278/1026/5780/207/7422/2625/5594/8878/4609/7314/6233/5595/5775/5717 71 Murine_coronavirus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 23/365 32/10654 2.12984295957461e-27 3.118698619377107e-25 1.6526300257751861e-25 4089/57154/7048/11171/7311/23327/9110/867/7046/4088/7040/64750/7316/51377/2280/9958/10273/56937/4087/4092/7314/6233/9372 23 Murine_coronavirus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 20/365 26/10654 5.669176643801202e-25 7.263632574870289e-23 3.849072563422921e-23 57154/7048/11171/7311/23327/9110/7046/4088/7040/64750/7316/51377/9958/10273/56937/4087/4092/7314/6233/9372 20 Murine_coronavirus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 25/365 47/10654 7.747367227868359e-25 8.823390453961186e-23 4.675604081380202e-23 10014/8454/6500/22938/8850/7311/3091/1387/26508/2033/7316/9978/2648/892/9611/3066/3065/4851/23462/9759/9612/1024/4609/7314/6233 25 Murine_coronavirus R-HSA-5663202 Diseases of signal transduction 59/365 377/10654 1.6391647425895385e-23 1.680143861154277e-21 8.903252707117915e-22 4089/10014/7249/8454/6500/22938/7048/1147/2308/8850/7311/818/2932/867/1387/3932/5518/7046/4088/60/5290/7040/3164/3667/26508/2335/2033/2309/7316/1499/9978/2648/10018/892/9611/8312/5781/3066/3065/6774/4851/2280/23462/9759/9612/1026/207/1024/4087/2099/5594/4303/4609/7314/6233/5595/5717/1027/9372 59 Murine_coronavirus R-HSA-8878159 Transcriptional regulation by RUNX3 30/365 96/10654 2.9916245979355286e-21 2.787650193530834e-19 1.4772041076887394e-19 4089/22938/57154/8850/7311/25937/51176/1387/4088/7040/64750/2033/2309/7316/1499/2648/10018/1029/865/864/4851/7157/9759/861/1026/10413/4609/7314/6233/5717 30 Murine_coronavirus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 24/365 58/10654 1.433596808124821e-20 9.183979552049634e-19 4.86668390126584e-19 10014/8454/6500/22938/8850/7311/1387/26508/2033/7316/9978/2648/892/9611/3066/3065/4851/23462/9759/9612/1024/4609/7314/6233 24 Murine_coronavirus R-HSA-2644603 Signaling by NOTCH1 in Cancer 24/365 58/10654 1.433596808124821e-20 9.183979552049634e-19 4.86668390126584e-19 10014/8454/6500/22938/8850/7311/1387/26508/2033/7316/9978/2648/892/9611/3066/3065/4851/23462/9759/9612/1024/4609/7314/6233 24 Murine_coronavirus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 24/365 58/10654 1.433596808124821e-20 9.183979552049634e-19 4.86668390126584e-19 10014/8454/6500/22938/8850/7311/1387/26508/2033/7316/9978/2648/892/9611/3066/3065/4851/23462/9759/9612/1024/4609/7314/6233 24 Murine_coronavirus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 24/365 58/10654 1.433596808124821e-20 9.183979552049634e-19 4.86668390126584e-19 10014/8454/6500/22938/8850/7311/1387/26508/2033/7316/9978/2648/892/9611/3066/3065/4851/23462/9759/9612/1024/4609/7314/6233 24 Murine_coronavirus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 24/365 58/10654 1.433596808124821e-20 9.183979552049634e-19 4.86668390126584e-19 10014/8454/6500/22938/8850/7311/1387/26508/2033/7316/9978/2648/892/9611/3066/3065/4851/23462/9759/9612/1024/4609/7314/6233 24 Murine_coronavirus R-HSA-201451 Signaling by BMP 18/365 28/10654 2.6849899513168727e-20 1.6188910000587028e-18 8.578667584393229e-19 4089/4093/57154/4086/658/92/650/64750/659/7323/9765/93/7321/6497/4091/4092/4090/657 18 Murine_coronavirus R-HSA-1980143 Signaling by NOTCH1 26/365 73/10654 3.2815020953634334e-20 1.8686331376375105e-18 9.902076498289658e-19 10014/8454/6500/22938/8850/7311/3091/1387/26508/2033/7316/9978/2648/892/9611/3066/3065/4851/83737/23462/9759/9612/1024/4609/7314/6233 26 Murine_coronavirus R-HSA-8878166 Transcriptional regulation by RUNX2 32/365 121/10654 3.972785946765996e-20 2.1432134712816557e-18 1.1357105532029108e-18 4089/8454/6500/57154/4086/7311/25937/367/2932/860/1019/650/2908/6662/7316/9978/865/11059/23462/9759/861/1026/10273/207/4091/10413/2099/5594/7314/6233/5595/5717 32 Murine_coronavirus R-HSA-9008059 Interleukin-37 signaling 16/365 21/10654 4.53910625051383e-20 2.3262919533883378e-18 1.2327256975079664e-18 5778/834/5777/25930/4088/84867/5784/26469/5771/5782/5783/5781/27178/6774/5780/5775 16 Murine_coronavirus R-HSA-166166 MyD88-independent TLR4 cascade 29/365 99/10654 1.0677243579454683e-19 4.974624849518659e-18 2.6361041564586677e-18 8454/6500/1147/2353/3665/7311/1432/3725/4208/8945/5518/1386/5601/351/7099/5602/6885/5599/7323/5606/7316/7321/5781/5970/5594/7314/6233/5595/10010 29 Murine_coronavirus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 29/365 99/10654 1.0677243579454683e-19 4.974624849518659e-18 2.6361041564586677e-18 8454/6500/1147/2353/3665/7311/1432/3725/4208/8945/5518/1386/5601/351/7099/5602/6885/5599/7323/5606/7316/7321/5781/5970/5594/7314/6233/5595/10010 29 Murine_coronavirus R-HSA-1257604 PIP3 activates AKT signaling 45/365 264/10654 1.476560874764894e-19 6.580325637539202e-18 3.4869812877743035e-18 10014/7249/1912/5931/1147/2308/7311/5928/3725/2932/3932/5518/57761/1386/5290/4615/3164/3667/23512/2309/7316/5468/7874/6615/5781/3630/2146/3066/3065/7157/1026/10273/207/4734/5371/2099/5594/4303/7314/2122/6233/5595/11060/5717/1027 45 Murine_coronavirus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 32/365 129/10654 3.268534730980206e-19 1.3959367080227964e-017 7.397210180639414e-18 8454/6500/1147/2353/3665/7311/1432/3725/4208/8945/5518/1386/5601/351/7099/4615/5602/6885/5599/7323/5606/7316/3929/7321/5781/5970/5594/7314/6233/5595/10010/5775 32 Murine_coronavirus R-HSA-9614085 FOXO-mediated transcription 24/365 65/10654 3.5652974463931966e-19 1.4617719530212107e-17 7.746077820374273e-18 4089/2308/8850/9314/10370/1387/4088/857/2908/25942/2290/2033/2309/10018/4802/3630/3066/3065/2660/1026/207/4087/4303/1027 24 Murine_coronavirus R-HSA-2262752 Cellular responses to stress 60/365 479/10654 6.766018251928443e-19 2.6673725800871743e-17 1.4134677805648084e-17 1912/5931/2353/10294/1017/1030/7311/818/3091/5928/10370/367/9972/1432/3725/2932/1051/1387/2034/1019/5601/2908/8021/6117/5602/8881/5599/2033/23512/7323/5606/7316/9978/3312/1029/7027/7321/2113/405/2146/9531/6774/7157/5970/50507/1026/23135/6667/10393/7422/8091/5594/3308/7314/996/6233/5595/5717/1027/4194 60 Murine_coronavirus R-HSA-2559583 Cellular Senescence 38/365 195/10654 1.0476765423002014e-18 3.9772905772507644e-17 2.1076066114109318e-17 1912/5931/2353/1017/1030/7311/5928/1432/3725/1051/1019/5601/5602/8881/5599/23512/5606/7316/1029/7027/7321/2113/2146/6774/7157/5970/1026/23135/6667/10393/8091/5594/7314/996/6233/5595/1027/4194 38 Murine_coronavirus R-HSA-9006925 Intracellular signaling by second messengers 47/365 305/10654 1.5378980477117007e-18 5.629805353230332e-17 2.9832909496963815e-17 10014/7249/1912/5931/1147/2308/7311/818/5928/3725/2932/3932/3838/5518/57761/1386/5290/4615/3164/3667/23512/2309/7316/5468/7874/6615/5781/3630/2146/3066/3065/7157/1026/10273/207/4734/5371/2099/5594/4303/7314/2122/6233/5595/11060/5717/1027 47 Murine_coronavirus R-HSA-8953897 Cellular responses to external stimuli 60/365 493/10654 2.8155946112137774e-18 9.95167060860042e-17 5.273491177445768e-17 1912/5931/2353/10294/1017/1030/7311/818/3091/5928/10370/367/9972/1432/3725/2932/1051/1387/2034/1019/5601/2908/8021/6117/5602/8881/5599/2033/23512/7323/5606/7316/9978/3312/1029/7027/7321/2113/405/2146/9531/6774/7157/5970/50507/1026/23135/6667/10393/7422/8091/5594/3308/7314/996/6233/5595/5717/1027/4194 60 Murine_coronavirus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 27/365 94/10654 3.587877368706384e-18 1.225858100974681e-16 6.4959463938684e-17 8454/6500/1147/2353/3665/7311/1432/3725/4208/8945/5518/1386/5601/351/5602/6885/5599/7323/5606/7316/7321/5970/5594/7314/6233/5595/10010 27 Murine_coronavirus R-HSA-446652 Interleukin-1 family signaling 32/365 140/10654 4.564193125991879e-18 1.5091283723037664e-16 7.997024288664888e-17 8454/6500/1147/5778/7311/834/5777/8945/25930/351/4088/4615/6885/5599/84867/5784/7316/9978/26469/5771/5782/5783/5781/27178/6774/5970/5780/8878/7314/6233/5775/5717 32 Murine_coronavirus R-HSA-168898 Toll-like Receptor Cascades 33/365 155/10654 1.3486965304149569e-17 4.3200435739854087e-16 2.289234900309598e-16 8454/6500/1147/2353/3665/7311/1432/3725/4208/8945/5518/1386/5601/351/7099/4615/5602/338/6885/5599/7323/5606/7316/3929/7321/5781/5970/5594/7314/6233/5595/10010/5775 33 Murine_coronavirus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 26/365 93/10654 3.221508229373756e-17 9.711899809141471e-16 5.146434199247239e-16 8454/6500/1147/2353/3665/7311/1432/3725/4208/8945/5518/1386/5601/351/7099/4615/5602/6885/5599/5606/7316/5970/5594/7314/6233/5595 26 Murine_coronavirus R-HSA-975155 MyD88 dependent cascade initiated on endosome 26/365 93/10654 3.221508229373756e-17 9.711899809141471e-16 5.146434199247239e-16 8454/6500/1147/2353/3665/7311/1432/3725/4208/8945/5518/1386/5601/351/7099/4615/5602/6885/5599/5606/7316/5970/5594/7314/6233/5595 26 Murine_coronavirus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 26/365 97/10654 1.0136320633306361e-16 2.968493899754006e-15 1.5730350215897992e-15 8454/6500/1147/2353/3665/7311/1432/3725/4208/8945/5518/1386/5601/351/7099/4615/5602/6885/5599/5606/7316/5970/5594/7314/6233/5595 26 Murine_coronavirus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 25/365 92/10654 2.8081184673221005e-16 7.995337302792092e-15 4.236810319117555e-15 8454/6500/1147/2353/7311/1432/3725/4208/8945/5518/1386/5601/351/7099/4615/5602/6885/5599/5606/7316/5970/5594/7314/6233/5595 25 Murine_coronavirus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 34/365 182/10654 2.9777180108288975e-16 8.249083678647621e-15 4.371273096977841e-15 672/1912/367/9972/1387/10499/9063/10401/6670/2908/25942/8021/6117/2033/23512/5468/7021/142/1029/28996/1655/3066/3065/7157/5970/3190/9759/8648/9612/7421/668/5371/2099/51588 34 Murine_coronavirus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 24/365 85/10654 4.2883993044659038e-016 1.0989023217693879e-14 5.823194845011596e-15 8454/6500/1147/2353/7311/1432/3725/4208/8945/5518/1386/5601/351/4615/5602/6885/5599/5606/7316/5970/5594/7314/6233/5595 24 Murine_coronavirus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 24/365 85/10654 4.2883993044659038e-016 1.0989023217693879e-14 5.823194845011596e-15 8454/6500/1147/2353/7311/1432/3725/4208/8945/5518/1386/5601/351/4615/5602/6885/5599/5606/7316/5970/5594/7314/6233/5595 24 Murine_coronavirus R-HSA-975871 MyD88 cascade initiated on plasma membrane 24/365 85/10654 4.2883993044659038e-016 1.0989023217693879e-14 5.823194845011596e-15 8454/6500/1147/2353/7311/1432/3725/4208/8945/5518/1386/5601/351/4615/5602/6885/5599/5606/7316/5970/5594/7314/6233/5595 24 Murine_coronavirus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 25/365 95/10654 6.463683383866332e-16 1.5774465401102357e-14 8.359049188157963e-15 8454/6500/1147/2353/7311/1432/3725/4208/8945/5518/1386/5601/351/7099/4615/5602/6885/5599/5606/7316/5970/5594/7314/6233/5595 25 Murine_coronavirus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 25/365 95/10654 6.463683383866332e-16 1.5774465401102357e-14 8.359049188157963e-15 8454/6500/1147/2353/7311/1432/3725/4208/8945/5518/1386/5601/351/7099/4615/5602/6885/5599/5606/7316/5970/5594/7314/6233/5595 25 Murine_coronavirus R-HSA-2990846 SUMOylation 34/365 188/10654 8.330049353438564e-16 1.9856512993661695e-14 1.052216760434345e-14 672/1912/367/9972/1387/10499/9063/10401/6670/2908/25942/8021/6117/2033/23512/5468/7021/142/1029/28996/1655/3066/3065/7157/5970/3190/9759/8648/9612/7421/668/5371/2099/51588 34 Murine_coronavirus R-HSA-450294 MAP kinase activation 21/365 64/10654 1.0283326644319215e-15 2.395547684187999e-14 1.2694250115953865e-14 8454/6500/1147/2353/7311/1432/3725/4208/8945/5518/1386/5601/5602/6885/5599/5606/7316/5594/7314/6233/5595 21 Murine_coronavirus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 25/365 98/10654 1.4388561875842511e-15 3.206146939725777e-14 1.698969777559436e-14 8454/6500/1147/2353/7311/1432/3725/4208/8945/5518/1386/5601/351/7099/4615/5602/6885/5599/5606/7316/5970/5594/7314/6233/5595 25 Murine_coronavirus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 25/365 98/10654 1.4388561875842511e-15 3.206146939725777e-14 1.698969777559436e-14 8454/6500/1147/2353/7311/1432/3725/4208/8945/5518/1386/5601/351/7099/4615/5602/6885/5599/5606/7316/5970/5594/7314/6233/5595 25 Murine_coronavirus R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 23/365 84/10654 3.7569480098965764e-015 8.193344064136151e-14 4.3417361099812615e-14 9314/1052/1051/1387/10499/23054/1019/10001/7040/688/2033/5468/892/9611/6721/51586/8202/1050/5970/8648/9612/1024/9862 23 Murine_coronavirus R-HSA-1181150 Signaling by NODAL 13/365 20/10654 4.52926372137503e-15 9.67186523835293e-14 5.1252194741875345e-14 4089/6997/8928/92/4088/130399/10589/2309/4838/91/93/55997/4087 13 Murine_coronavirus R-HSA-1502540 Signaling by Activin 11/365 13/10654 4.830006772231251e-15 1.0103585594973535e-13 5.353992469326156e-14 4089/8928/92/4088/130399/10589/91/93/3624/4087/3625 11 Murine_coronavirus R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 12/365 17/10654 1.160706848718292e-14 2.3794490398724986e-13 1.2608941767129238e-13 4089/2308/9314/4088/857/2290/2309/2660/1026/4087/4303/1027 12 Murine_coronavirus R-HSA-448424 Interleukin-17 signaling 21/365 72/10654 1.5035899672683985e-14 3.0219210126472715e-13 1.6013465905273347e-13 8454/6500/1147/2353/7311/1432/3725/4208/8945/5518/1386/5601/5602/6885/5599/5606/7316/5594/7314/6233/5595 21 Murine_coronavirus R-HSA-157118 Signaling by NOTCH 36/365 235/10654 2.5090075195738996e-14 4.945639822237013e-13 2.6207446965589724e-13 10014/8454/6500/22938/8850/7311/3091/3725/1387/4088/26508/2033/4855/7316/9978/2648/892/9611/7027/3066/3065/4851/7157/83737/23462/9759/9612/861/207/1024/4904/4609/7314/6233/11060/5717 36 Murine_coronavirus R-HSA-5688426 Deubiquitination 40/365 297/10654 7.028272111534246e-14 1.35924130458917e-12 7.202757516487926e-13 4089/672/7048/4086/8850/7311/3091/367/7046/4088/7706/60/7040/64750/9146/6885/2033/8239/7316/2648/993/8312/7874/7321/51377/7157/9958/4087/4092/55611/2625/9817/2099/4303/4609/7314/6233/5717/7528/4194 40 Murine_coronavirus R-HSA-6807070 PTEN Regulation 27/365 140/10654 1.7222062190147253e-13 3.269002545352025e-12 1.7322776004124723e-12 10014/1912/5931/7311/5928/3725/1386/23512/7316/5468/7874/6615/2146/3066/3065/7157/10273/207/4734/5371/5594/7314/2122/6233/5595/11060/5717 27 Murine_coronavirus R-HSA-69231 Cyclin D associated events in G1 16/365 44/10654 4.5197048021913557e-13 8.272673968296678e-12 4.383773830696879e-12 8454/6500/1030/7311/5518/1019/1874/7316/1875/1029/7027/1026/5933/7314/6233/1027 16 Murine_coronavirus R-HSA-69236 G1 Phase 16/365 44/10654 4.5197048021913557e-13 8.272673968296678e-12 4.383773830696879e-12 8454/6500/1030/7311/5518/1019/1874/7316/1875/1029/7027/1026/5933/7314/6233/1027 16 Murine_coronavirus R-HSA-450341 Activation of the AP-1 family of transcription factors 9/365 10/10654 5.728567725118246e-13 1.0301371786396845e-11 5.458801377952012e-12 2353/1432/3725/1386/5601/5602/5599/5594/5595 9 Murine_coronavirus R-HSA-2559580 Oxidative Stress Induced Senescence 25/365 125/10654 5.904632388008453e-13 1.0434910685704593e-11 5.529564994940765e-12 1912/5931/2353/1030/7311/5928/1432/3725/1019/5601/5602/5599/23512/5606/7316/1029/7027/2146/7157/23135/5594/7314/6233/5595/4194 25 Murine_coronavirus R-HSA-8939211 ESR-mediated signaling 33/365 223/10654 8.660242265589196e-13 1.5045336139371062e-11 7.972676198116013e-12 3727/1025/2353/51523/8850/3725/1387/4318/10499/3838/1386/857/5290/2033/4435/2309/904/865/8312/1655/3065/8202/8648/861/207/6667/2625/2099/5594/4609/5595/7528/1027 33 Murine_coronavirus R-HSA-2559585 Oncogene Induced Senescence 14/365 33/10654 1.0870733109850264e-12 1.8570835729327535e-11 9.840874183653923e-12 1030/7311/1019/7316/1029/7027/2113/7157/6667/5594/7314/6233/5595/4194 14 Murine_coronavirus R-HSA-400253 Circadian Clock 19/365 70/10654 1.1695225208019317e-12 1.9651812849540652e-11 1.0413694922067243e-11 8454/6500/7311/3091/4208/8945/1387/10499/23054/1386/2908/2033/7316/1453/9611/8648/7314/6233/5054 19 Murine_coronavirus R-HSA-453279 Mitotic G1-G1/S phases 26/365 149/10654 5.512514830293729e-12 9.113431775888825e-11 4.829299919238649e-11 8454/6500/1017/1030/7311/5928/5518/1019/4149/6117/1874/7316/1875/1029/993/7027/3065/1859/1026/207/5933/4609/7314/6233/5717/1027 26 Murine_coronavirus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 10/365 16/10654 1.3150829016632862e-11 2.0925415823871506e-10 1.1088590054036145e-10 57154/7048/7311/56288/7046/7040/7316/2280/7314/6233 10 Murine_coronavirus R-HSA-3247509 Chromatin modifying enzymes 35/365 274/10654 1.3269775888308758e-11 2.0925415823871506e-10 1.1088590054036145e-10 5931/8850/284058/5928/1387/10499/1019/1386/6599/60/8289/2033/79595/23512/6597/8819/2648/6601/9611/10284/8242/2146/3066/3065/5970/8648/9612/29072/23135/63976/6839/2122/5929/9757/22992 35 Murine_coronavirus R-HSA-4839726 Chromatin organization 35/365 274/10654 1.3269775888308758e-11 2.0925415823871506e-10 1.1088590054036145e-10 5931/8850/284058/5928/1387/10499/1019/1386/6599/60/8289/2033/79595/23512/6597/8819/2648/6601/9611/10284/8242/2146/3066/3065/5970/8648/9612/29072/23135/63976/6839/2122/5929/9757/22992 35 Murine_coronavirus R-HSA-8878171 Transcriptional regulation by RUNX1 32/365 239/10654 3.004901809581371e-11 4.666703567910463e-10 2.472933546641128e-10 1912/8850/7311/860/1387/6938/6599/25942/8289/2033/6597/7316/50943/6601/6929/865/8312/28996/5781/3065/83737/861/10413/5371/23309/2625/2099/7314/6233/5717/5929/9757 32 Murine_coronavirus R-HSA-69202 Cyclin E associated events during G1/S transition 19/365 83/10654 3.130866202556587e-11 4.78975799644851e-10 2.5381413362438317e-10 8454/6500/1017/7311/5928/1019/4149/1874/7316/1875/993/7027/1026/207/4609/7314/6233/5717/1027 19 Murine_coronavirus R-HSA-69242 S Phase 26/365 161/10654 3.404222653404716e-11 5.131365029029168e-10 2.719162367115841e-10 8454/6500/1017/7311/5928/2932/1019/4149/6117/8881/1874/7316/9978/1875/993/7027/7321/1026/207/10393/4609/7314/996/6233/5717/1027 26 Murine_coronavirus R-HSA-9018519 Estrogen-dependent gene expression 25/365 150/10654 4.054582526430777e-11 5.937190283522915e-10 3.146177341512528e-10 3727/1025/2353/51523/8850/3725/1387/10499/3838/1386/2033/4435/904/865/8312/1655/3065/8202/8648/861/6667/2625/2099/4609/7528 25 Murine_coronavirus R-HSA-350054 Notch-HLH transcription pathway 12/365 28/10654 4.05466653508882e-11 5.937190283522915e-10 3.146177341512528e-10 10014/22938/8850/1387/4855/2648/9611/3066/3065/4851/9759/9612 12 Murine_coronavirus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 19/365 85/10654 4.893665668939327e-11 7.06479902910255e-10 3.743708651108514e-10 8454/6500/1017/7311/5928/1019/4149/1874/7316/1875/993/7027/1026/207/4609/7314/6233/5717/1027 19 Murine_coronavirus R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 14/365 42/10654 5.2983451425770013e-11 7.542783015474203e-10 3.9969972128212464e-10 7311/6736/51176/8945/6662/7316/1499/3065/207/57680/7314/6233/4221/5929 14 Murine_coronavirus R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 22/365 119/10654 7.664526659829596e-11 1.0703899977392813e-9 5.672105148482354e-10 1387/10499/23054/57761/10001/25942/2033/5468/892/4802/9611/6721/405/51586/8202/8648/9612/1024/6667/23309/9862/2274 22 Murine_coronavirus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 21/365 108/10654 7.7276936422153e-11 1.0703899977392813e-9 5.672105148482354e-10 2353/2308/3091/1052/4318/7076/3726/7040/6935/2335/2309/3312/3929/6774/7157/1278/1026/207/7422/2625/4609 21 Murine_coronavirus R-HSA-69206 G1/S Transition 23/365 131/10654 8.415849200949091e-11 1.1501660574630424e-9 6.094846579213658e-10 8454/6500/1017/7311/5928/5518/1019/4149/6117/1874/7316/1875/993/7027/3065/1026/207/5933/4609/7314/6233/5717/1027 23 Murine_coronavirus R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 21/365 110/10654 1.1110004380352444e-10 1.4983887486659546e-9 7.940113933880694e-10 2353/1017/1030/7311/3725/1051/1019/8881/7316/1029/7321/6774/5970/1026/10393/5594/7314/996/6233/5595/1027 21 Murine_coronavirus R-HSA-8943724 Regulation of PTEN gene transcription 16/365 61/10654 1.2913183827347052e-10 1.718962782211783e-9 9.108958106508652e-10 10014/1912/5931/5928/3725/1386/23512/5468/6615/2146/3066/3065/7157/5594/2122/5595 16 Murine_coronavirus R-HSA-9006931 Signaling by Nuclear Receptors 35/365 299/10654 1.5761740503942512e-10 2.0712543610950095e-9 1.0975786909627985e-9 3727/1025/2353/51523/8850/3725/1387/4318/10499/3838/1386/857/5290/2033/4435/2309/904/9611/865/8312/1655/3065/8202/8648/9612/861/207/6667/2625/2099/5594/4609/5595/7528/1027 35 Murine_coronavirus R-HSA-3700989 Transcriptional Regulation by TP53 39/365 365/10654 2.1099850784707668e-10 2.7376388676361215e-9 1.4507025989219396e-9 7249/672/5931/1025/2353/1017/7311/834/5928/1432/3725/1387/8812/5518/1386/5325/5300/28984/6117/2033/1874/904/7316/905/1029/7027/28996/7874/3066/3065/7157/1026/207/5933/5371/7314/6233/1027/4194 39 Murine_coronavirus R-HSA-9013694 Signaling by NOTCH4 18/365 82/10654 2.1980912801085217e-10 2.8163044526390433e-9 1.4923882901789437e-9 8454/6500/22938/8850/7311/1387/4088/2033/4855/7316/9978/2648/4851/23462/207/7314/6233/5717 18 Murine_coronavirus R-HSA-8939902 Regulation of RUNX2 expression and activity 17/365 73/10654 2.611568323502484e-10 3.3047623846790695e-9 1.7512271019197945e-9 8454/6500/57154/7311/2932/860/650/2908/7316/9978/865/11059/10273/2099/7314/6233/5717 17 Murine_coronavirus R-HSA-8941326 RUNX2 regulates bone development 12/365 32/10654 2.658047794733496e-10 3.32255974341687e-9 1.7606581028016481e-9 4089/4086/25937/367/860/865/23462/9759/4091/10413/5594/5595 12 Murine_coronavirus R-HSA-5689880 Ub-specific processing proteases 29/365 220/10654 3.857672928767283e-10 4.7639936770921264e-9 2.5244885621355967e-9 4089/4086/7311/3091/367/7046/4088/64750/9146/6885/8239/7316/2648/993/8312/7874/7157/9958/4087/4092/55611/2625/9817/4303/4609/7314/6233/5717/4194 29 Murine_coronavirus R-HSA-1538133 G0 and Early G1 11/365 27/10654 5.236248545731588e-10 6.389469951636759e-9 3.385844924307644e-9 1017/5928/4149/1874/1875/993/7027/3065/1859/5933/4609 11 Murine_coronavirus R-HSA-9012852 Signaling by NOTCH3 14/365 49/10654 5.439878599690421e-10 6.5032174773220265e-9 3.4461208917054327e-9 22938/8850/7311/1387/26508/2033/7316/2648/4851/23462/4904/7314/6233/11060 14 Murine_coronavirus R-HSA-1295596 Spry regulation of FGF signaling 9/365 16/10654 5.456358078533603e-10 6.5032174773220265e-9 3.4461208917054327e-9 7311/867/5518/7316/5781/5594/7314/6233/5595 9 Murine_coronavirus R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 11/365 29/10654 1.3062417220798793e-9 1.538962948427444e-8 8.15512073313028e-9 4089/2308/4088/2908/25942/2309/3630/3066/3065/4087/4303 11 Murine_coronavirus R-HSA-1989781 PPARA activates gene expression 20/365 117/10654 2.3981000797006162e-9 2.7932415701058315e-8 1.4801670348391364e-8 1387/10499/23054/57761/10001/2033/5468/892/4802/9611/6721/405/51586/8202/8648/9612/1024/6667/9862/2274 20 Murine_coronavirus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 12/365 38/10654 2.6459893138211347e-9 3.047347243445689e-8 1.6148202080800774e-8 10370/51741/1387/5308/2033/4435/7021/1026/7422/2099/4609/7528 12 Murine_coronavirus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 11/365 31/10654 3.005383145561955e-9 3.422797471334449e-8 1.813775091356689e-8 2353/1432/3725/4208/5518/1386/5601/5602/5599/5594/5595 11 Murine_coronavirus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 43/365 473/10654 3.8427660382308055e-9 4.328390317787446e-8 2.2936579244963514e-8 1281/7311/1432/5777/4208/51741/867/3932/4318/5518/57761/60/857/5290/3667/9146/2335/7316/1499/5340/26469/9611/5771/5782/9047/5781/3630/6774/11059/83737/1278/10048/10273/207/4734/10413/7422/2099/5594/7314/6233/5595/7410 43 Murine_coronavirus R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 9/365 19/10654 4.020719541804641e-9 4.479606011249736e-8 2.3737886539716186e-8 5928/4149/1874/1875/993/7027/3065/5933/4609 9 Murine_coronavirus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 10/365 25/10654 4.070882218053161e-9 4.486725025273645e-8 2.3775610916982806e-8 7249/1147/2308/2932/3164/2309/1026/207/4303/1027 10 Murine_coronavirus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 21/365 134/10654 4.8534643421982124e-9 5.2923414369714545e-8 2.8044653981794823e-8 8454/6500/1147/2353/7311/3725/8945/5601/5290/5602/6885/5599/7316/7321/5970/5594/7314/6233/5595/5717/7410 21 Murine_coronavirus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 16/365 78/10654 6.431430996929699e-9 6.939175549318885e-8 3.677139495197479e-8 1147/3665/7311/1387/351/7706/5300/2033/7323/7316/7321/5970/83737/7314/6233/10010 16 Murine_coronavirus R-HSA-201681 TCF dependent signaling in response to WNT 28/365 233/10654 6.505520653268459e-9 6.945998614166845e-8 3.6807551064545234e-8 7311/6736/2932/51176/8945/1387/5518/1455/857/64750/6662/2033/6597/7316/1499/9978/8312/864/3065/207/57680/4609/7314/6233/1855/4221/5717/5929 28 Murine_coronavirus R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 9/365 20/10654 7.090884338064516e-9 7.492944790222813e-8 3.970587431840792e-8 22938/8850/1387/4088/2033/4855/2648/4851/23462 9 Murine_coronavirus R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 7/365 11/10654 1.5340844351461956e-8 1.588319743459445e-7 8.416667395379448e-8 3091/10370/1387/2034/2033/405/7422 7 Murine_coronavirus R-HSA-1433617 Regulation of signaling by NODAL 7/365 11/10654 1.5340844351461956e-8 1.588319743459445e-7 8.416667395379448e-8 6997/92/130399/4838/91/93/55997 7 Murine_coronavirus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 8/365 16/10654 1.7798820321716393e-8 1.8063159237385446e-7 9.571851262121583e-8 8454/6500/1147/7311/8945/7316/7314/6233 8 Murine_coronavirus R-HSA-9614657 FOXO-mediated transcription of cell death genes 8/365 16/10654 1.7798820321716393e-8 1.8063159237385446e-7 9.571851262121583e-8 2308/10370/1387/2033/2309/10018/4802/4303 8 Murine_coronavirus R-HSA-6804757 Regulation of TP53 Degradation 11/365 36/10654 1.8275589221331985e-8 1.836517544300518e-7 9.731892712288239e-8 1017/7311/5518/7316/1029/7874/7157/207/7314/6233/4194 11 Murine_coronavirus R-HSA-8848021 Signaling by PTK6 13/365 54/10654 2.2463240538065584e-8 2.2086323193087044e-7 1.1703766641985021e-7 1017/7311/3091/867/2034/1019/2908/7316/6774/207/7314/6233/1027 13 Murine_coronavirus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 13/365 54/10654 2.2463240538065584e-8 2.2086323193087044e-7 1.1703766641985021e-7 1017/7311/3091/867/2034/1019/2908/7316/6774/207/7314/6233/1027 13 Murine_coronavirus R-HSA-3899300 SUMOylation of transcription cofactors 12/365 45/10654 2.262501400267453e-8 2.2086323193087044e-7 1.1703766641985021e-7 1912/1387/10499/9063/10401/25942/2033/28996/1655/8648/9612/51588 12 Murine_coronavirus R-HSA-5633007 Regulation of TP53 Activity 22/365 160/10654 2.486292591151267e-8 2.40419802446231e-7 1.2740089146316322e-7 672/5931/1017/7311/5928/1432/5518/5300/6117/2033/7316/1029/28996/7874/3066/3065/7157/207/5371/7314/6233/4194 22 Murine_coronavirus R-HSA-6806003 Regulation of TP53 Expression and Degradation 11/365 37/10654 2.5217501128043844e-8 2.415695201518219e-7 1.280101385348807e-7 1017/7311/5518/7316/1029/7874/7157/207/7314/6233/4194 11 Murine_coronavirus R-HSA-1234174 Cellular response to hypoxia 15/365 75/10654 2.7676335580939813e-8 2.6266892565243806e-7 1.3919092748308914e-7 7311/3091/10370/1387/2034/2033/7323/7316/9978/7321/405/7422/7314/6233/5717 15 Murine_coronavirus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 8/365 18/10654 5.697121765332775e-8 5.357385146299169e-7 2.8389327193739367e-7 3665/7311/7099/7316/5781/7314/6233/10010 8 Murine_coronavirus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 9/365 25/10654 7.406346134976454e-8 6.901367989409878e-7 3.657104885787417e-7 7311/9184/8881/7316/7321/10393/7314/996/6233 9 Murine_coronavirus R-HSA-195253 Degradation of beta-catenin by the destruction complex 15/365 82/10654 9.723682692110472e-8 8.979076359831743e-7 4.7581036217439584e-7 8454/6500/7311/2932/51176/8945/5518/7316/1499/9978/8312/3065/7314/6233/5717 15 Murine_coronavirus R-HSA-195721 Signaling by WNT 32/365 331/10654 1.0576941308137275e-7 9.679790036464916e-7 5.129418905074092e-7 8454/6500/57154/7311/6736/2932/51176/8945/1387/5518/1455/857/64750/6662/6885/2033/6597/7316/1499/9978/8312/864/3065/207/57680/4609/7314/6233/1855/4221/5717/5929 32 Murine_coronavirus R-HSA-186712 Regulation of beta-cell development 11/365 42/10654 1.0821441592509045e-7 9.81590940913431e-7 5.201549941066294e-7 22938/2308/8850/1387/2033/5080/2648/3172/3630/4851/207 11 Murine_coronavirus R-HSA-8941856 RUNX3 regulates NOTCH signaling 7/365 14/10654 1.4589969923274686e-7 1.3118174711716276e-6 6.951453813859406e-7 22938/8850/1387/2033/2648/864/4851 7 Murine_coronavirus R-HSA-3232118 SUMOylation of transcription factors 8/365 20/10654 1.54407195150198e-7 1.3643739226633876e-6 7.229955780172611e-7 9063/10401/6670/7021/1029/7157/668/51588 8 Murine_coronavirus R-HSA-8876384 Listeria monocytogenes entry into host cells 8/365 20/10654 1.54407195150198e-7 1.3643739226633876e-6 7.229955780172611e-7 7311/867/999/9146/7316/1499/7314/6233 8 Murine_coronavirus R-HSA-8941858 Regulation of RUNX3 expression and activity 12/365 55/10654 2.5324589812759e-7 2.218607227186152e-6 1.175662469040364e-6 57154/7311/7040/64750/2033/7316/1029/865/864/7314/6233/5717 12 Murine_coronavirus R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 6/365 10/10654 2.901841940763225e-7 2.5206677875273775e-6 1.3357274232237504e-006 2308/8850/1387/2033/2309/4303 6 Murine_coronavirus R-HSA-5654732 Negative regulation of FGFR3 signaling 9/365 29/10654 3.214626047438791e-7 2.768900587079631e-6 1.467268501086613e-6 7311/867/5518/7316/5781/5594/7314/6233/5595 9 Murine_coronavirus R-HSA-9616222 Transcriptional regulation of granulopoiesis 15/365 90/10654 3.4806379651291933e-7 2.9730449285478525e-6 1.5754466579005825e-6 1017/51176/1051/2313/1019/688/2033/7027/865/6774/1050/861/1026/5371/4609 15 Murine_coronavirus R-HSA-6806834 Signaling by MET 14/365 79/10654 3.935297968177595e-7 3.333620179654574e-6 1.7665191401301774e-6 1281/7311/867/5290/9146/2335/7316/5771/5781/6774/1278/10048/7314/6233 14 Murine_coronavirus R-HSA-4090294 SUMOylation of intracellular receptors 9/365 30/10654 4.4547742032940185e-7 3.712311836078349e-6 1.9671916892594896e-6 367/9063/10401/2908/5468/9759/7421/2099/51588 9 Murine_coronavirus R-HSA-6804758 Regulation of TP53 Activity through Acetylation 9/365 30/10654 4.4547742032940185e-7 3.712311836078349e-6 1.9671916892594896e-6 5931/5928/5300/2033/3066/3065/7157/207/5371 9 Murine_coronavirus R-HSA-193639 p75NTR signals via NF-kB 7/365 16/10654 4.5822089353593426e-7 3.7877130312446177e-6 2.0071475472371993e-6 7311/4615/7316/5970/8878/7314/6233 7 Murine_coronavirus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 14/365 80/10654 4.623891094870522e-7 3.7915906977938277e-6 2.0092023620658437e-6 8454/6500/1017/7311/9184/8945/8881/7316/7321/10393/7314/996/6233/5717 14 Murine_coronavirus R-HSA-1236394 Signaling by ERBB4 12/365 58/10654 4.6914860255898716e-7 3.816486647801284e-6 2.022394978449769e-6 7311/51741/5290/7316/9611/11059/83737/4734/10413/2099/7314/6233 12 Murine_coronavirus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 8/365 23/10654 5.490483958338395e-7 4.396676607263168e-6 2.329843521794911e-6 7311/8881/7316/7321/10393/7314/996/6233 8 Murine_coronavirus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 8/365 23/10654 5.490483958338395e-7 4.396676607263168e-6 2.329843521794911e-6 7311/5601/5602/6885/5599/7316/7314/6233 8 Murine_coronavirus R-HSA-5654733 Negative regulation of FGFR4 signaling 9/365 31/10654 6.089217821215913e-7 4.838331989725822e-6 2.5638811878803846e-6 7311/867/5518/7316/5781/5594/7314/6233/5595 9 Murine_coronavirus R-HSA-5654741 Signaling by FGFR3 10/365 40/10654 6.664984438143716e-7 5.255083883921008e-6 2.7847222429815047e-6 7311/867/5518/5290/7316/5781/5594/7314/6233/5595 10 Murine_coronavirus R-HSA-212165 Epigenetic regulation of gene expression 19/365 149/10654 7.474937555163731e-7 5.848710682475439e-6 3.0992911036275495e-6 5931/8850/5928/2932/29947/22823/60/25942/2033/79595/23512/8819/2648/10284/2146/3066/3065/6839/23309 19 Murine_coronavirus R-HSA-8940973 RUNX2 regulates osteoblast differentiation 8/365 24/10654 7.991395273195859e-7 6.205439511383148e-6 3.288325327726526e-6 25937/367/860/865/23462/10413/5594/5595 8 Murine_coronavirus R-HSA-5654743 Signaling by FGFR4 10/365 41/10654 8.549260499046964e-7 6.588715798137698e-6 3.4914273189617995e-6 7311/867/5518/5290/7316/5781/5594/7314/6233/5595 10 Murine_coronavirus R-HSA-5654726 Negative regulation of FGFR1 signaling 9/365 33/10654 1.0962020708104315e-6 8.385127780452928e-6 4.443364246175826e-6 7311/867/5518/7316/5781/5594/7314/6233/5595 9 Murine_coronavirus R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 8/365 25/10654 1.1403517936583247e-6 8.575036097354525e-6 4.5439985892014735e-6 22938/8850/1387/26508/2033/2648/4851/23462 8 Murine_coronavirus R-HSA-937041 IKK complex recruitment mediated by RIP1 8/365 25/10654 1.1403517936583247e-6 8.575036097354525e-6 4.5439985892014735e-6 1147/7311/7099/7323/7316/7321/7314/6233 8 Murine_coronavirus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 14/365 86/10654 1.1544926648145604e-6 8.575036097354525e-6 4.5439985892014735e-6 8454/6500/1017/7311/9184/8945/8881/7316/7321/10393/7314/996/6233/5717 14 Murine_coronavirus R-HSA-453276 Regulation of mitotic cell cycle 14/365 86/10654 1.1544926648145604e-6 8.575036097354525e-6 4.5439985892014735e-6 8454/6500/1017/7311/9184/8945/8881/7316/7321/10393/7314/996/6233/5717 14 Murine_coronavirus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 12/365 63/10654 1.2027434918527638e-6 8.754342520472139e-6 4.639014881194992e-6 1147/3665/7311/1387/4615/2033/7316/1499/2547/5970/7314/6233 12 Murine_coronavirus R-HSA-8866907 Activation of the TFAP2 (AP-2) family of transcription factors 6/365 12/10654 1.2042558979381187e-6 8.754342520472139e-6 4.639014881194992e-6 10370/51741/1387/2033/4435/7021 6 Murine_coronavirus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 6/365 12/10654 1.2042558979381187e-6 8.754342520472139e-6 4.639014881194992e-6 3665/7311/7316/7314/6233/10010 6 Murine_coronavirus R-HSA-73887 Death Receptor Signalling 18/365 141/10654 1.4421315719245276e-6 1.0294337792277319e-5 5.455073993134888e-6 1147/7311/26574/4615/6885/5599/8837/7316/10018/11108/3066/3065/5970/55072/8878/7314/6233/7410 18 Murine_coronavirus R-HSA-5654727 Negative regulation of FGFR2 signaling 9/365 34/10654 1.4462289191101795e-6 1.0294337792277319e-5 5.455073993134888e-6 7311/867/5518/7316/5781/5594/7314/6233/5595 9 Murine_coronavirus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 9/365 34/10654 1.4462289191101795e-6 1.0294337792277319e-5 5.455073993134888e-6 7311/7706/5300/7323/7316/7321/83737/7314/6233 9 Murine_coronavirus R-HSA-2219528 PI3K/AKT Signaling in Cancer 15/365 101/10654 1.6047065949622788e-6 1.1343615585078178e-5 6.0110969364830195e-6 7249/1147/2308/2932/3932/5290/3164/3667/2309/5781/1026/207/2099/4303/1027 15 Murine_coronavirus R-HSA-6804760 Regulation of TP53 Activity through Methylation 7/365 19/10654 1.8459934814253898e-6 1.2959885742883731e-5 6.867574884033895e-6 7311/2033/7316/7157/7314/6233/4194 7 Murine_coronavirus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 11/365 55/10654 2.027193327528962e-6 1.4135191569504669e-5 7.490381360579623e-6 1147/7311/834/1432/351/6885/7316/5970/83737/7314/6233 11 Murine_coronavirus R-HSA-9020702 Interleukin-1 signaling 15/365 103/10654 2.0690061745082466e-6 1.4329265735614546e-5 7.593223229347477e-6 8454/6500/1147/7311/8945/351/4615/6885/7316/9978/5970/8878/7314/6233/5717 15 Murine_coronavirus R-HSA-209543 p75NTR recruits signalling complexes 6/365 13/10654 2.1720560964849966e-6 1.484238332598081e-5 7.865129444114094e-6 7311/4615/7316/8878/7314/6233 6 Murine_coronavirus R-HSA-209560 NF-kB is activated and signals survival 6/365 13/10654 2.1720560964849966e-6 1.484238332598081e-5 7.865129444114094e-6 7311/7316/5970/8878/7314/6233 6 Murine_coronavirus R-HSA-168638 NOD1/2 Signaling Pathway 9/365 36/10654 2.4428476738349536e-6 1.6582244143581638e-5 8.78709933564891e-6 1147/7311/834/1432/6885/7316/83737/7314/6233 9 Murine_coronavirus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 7/365 20/10654 2.7568476355735723e-6 1.8590584384624418e-5 9.851339196370936e-6 1147/7311/7323/7316/7321/7314/6233 7 Murine_coronavirus R-HSA-69615 G1/S DNA Damage Checkpoints 12/365 68/10654 2.81250444803209e-6 1.8841941563613675e-5 9.984535914582446e-6 1017/7311/7316/1029/993/7157/1026/7314/6233/5717/1027/4194 12 Murine_coronavirus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 13/365 80/10654 2.85027497589887e-6 1.8970986040885335e-5 1.0052917891755412e-5 7311/9972/3837/3838/7706/5300/8021/7316/2316/4734/7314/6233/5595 13 Murine_coronavirus R-HSA-109581 Apoptosis 20/365 178/10654 2.8813663600807625e-6 1.905419689730827e-5 1.0097012168432418e-5 7311/3837/7099/999/5599/8837/7316/1499/4976/10018/1029/7027/6774/7157/207/5594/7314/6233/5595/5717 20 Murine_coronavirus R-HSA-198323 AKT phosphorylates targets in the cytosol 6/365 14/10654 3.6916733944241844e-6 2.4256187367210183e-5 1.2853599672893923e-5 7249/1147/2932/1026/207/1027 6 Murine_coronavirus R-HSA-5357801 Programmed Cell Death 20/365 181/10654 3.7341744952210757e-6 2.4379164698099378e-5 1.2918766607670634e-5 7311/3837/7099/999/5599/8837/7316/1499/4976/10018/1029/7027/6774/7157/207/5594/7314/6233/5595/5717 20 Murine_coronavirus R-HSA-5689896 Ovarian tumor domain proteases 9/365 38/10654 3.980762456408143e-6 2.555663374251004e-5 1.3542719395260776e-5 7311/7706/7316/7321/7157/55611/2099/7314/6233 9 Murine_coronavirus R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 9/365 38/10654 3.980762456408143e-6 2.555663374251004e-5 1.3542719395260776e-5 1912/6599/8289/2033/6597/6601/865/28996/861 9 Murine_coronavirus R-HSA-8863795 Downregulation of ERBB2 signaling 8/365 29/10654 4.012379735265397e-6 2.555663374251004e-5 1.3542719395260776e-5 7311/7316/26469/5782/10273/207/7314/6233 8 Murine_coronavirus R-HSA-6807004 Negative regulation of MET activity 7/365 21/10654 4.0142614951649915e-6 2.555663374251004e-5 1.3542719395260776e-5 7311/867/9146/7316/5771/7314/6233 7 Murine_coronavirus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 10/365 49/10654 4.906885143000566e-6 3.104664982454062e-5 1.6451934592516518e-5 1017/5325/28984/2033/1874/7027/7157/1026/5933/1027 10 Murine_coronavirus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 11/365 60/10654 4.9789895923761974e-6 3.1118684952351235e-5 1.6490106737266483e-5 8454/6500/1017/7311/1019/7316/1026/7314/6233/5717/1027 11 Murine_coronavirus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 11/365 60/10654 4.9789895923761974e-6 3.1118684952351235e-5 1.6490106737266483e-5 8454/6500/1147/7311/5971/8945/7316/5970/7314/6233/5717 11 Murine_coronavirus R-HSA-193704 p75 NTR receptor-mediated signalling 14/365 97/10654 5.0539297633856224e-006 3.139562428769856e-5 1.6636859699566067e-5 7311/26574/4615/5599/7316/10018/11108/3066/3065/5970/8878/7314/6233/7410 14 Murine_coronavirus R-HSA-1169408 ISG15 antiviral mechanism 12/365 72/10654 5.244460744392016e-6 3.238296543976998e-5 1.7160061788879394e-5 7311/9972/3837/3838/7706/5300/8021/7316/4734/7314/6233/5595 12 Murine_coronavirus R-HSA-202424 Downstream TCR signaling 14/365 98/10654 5.71590925512017e-6 3.5082676565857335e-5 1.8590666092921573e-5 8454/6500/1147/7311/8945/3932/5290/6885/7316/7321/5970/7314/6233/5717 14 Murine_coronavirus R-HSA-5654736 Signaling by FGFR1 10/365 50/10654 5.949084488920146e-6 3.581964300504743e-5 1.898119208277738e-5 7311/867/5518/5290/7316/5781/5594/7314/6233/5595 10 Murine_coronavirus R-HSA-2032785 YAP1- and WWTR1 (TAZ)-stimulated gene expression 6/365 15/10654 5.975764833037182e-6 3.581964300504743e-5 1.898119208277738e-5 8850/25937/860/2626/28996/10413 6 Murine_coronavirus R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 6/365 15/10654 5.975764833037182e-6 3.581964300504743e-5 1.898119208277738e-5 7311/867/9146/7316/7314/6233 6 Murine_coronavirus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 6/365 15/10654 5.975764833037182e-6 3.581964300504743e-5 1.898119208277738e-5 3665/7311/4615/7316/7314/6233 6 Murine_coronavirus R-HSA-8986944 Transcriptional Regulation by MECP2 11/365 62/10654 6.944537522101896e-6 4.138459860554909e-5 2.1930118490848093e-5 818/4208/25942/2290/5468/9611/28996/3066/3065/9612/5775 11 Murine_coronavirus R-HSA-2871796 FCERI mediated MAPK activation 8/365 32/10654 8.985250444869461e-6 5.323631043925548e-5 2.8210460782188266e-5 2353/3725/5601/5602/5599/5594/5595/7410 8 Murine_coronavirus R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 6/365 16/10654 9.286291196737912e-6 5.377654506585514e-5 2.849673658945443e-5 5928/1874/1875/7027/3065/5933 6 Murine_coronavirus R-HSA-205043 NRIF signals cell death from the nucleus 6/365 16/10654 9.286291196737912e-6 5.377654506585514e-5 2.849673658945443e-5 7311/5599/7316/8878/7314/6233 6 Murine_coronavirus R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 6/365 16/10654 9.286291196737912e-6 5.377654506585514e-5 2.849673658945443e-5 22938/8850/1387/2033/2648/4851 6 Murine_coronavirus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 6/365 16/10654 9.286291196737912e-6 5.377654506585514e-5 2.849673658945443e-5 7311/7099/6885/7316/7314/6233 6 Murine_coronavirus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 5/365 10/10654 1.0041626242314437e-5 5.7823971339170215e-5 3.064150881747042e-5 7311/6885/7316/7314/6233 5 Murine_coronavirus R-HSA-69052 Switching of origins to a post-replicative state 13/365 90/10654 1.090514361381668e-5 6.224406890922145e-5 3.298376334496356e-5 8454/6500/1017/7311/8881/7316/9978/7321/10393/7314/996/6233/5717 13 Murine_coronavirus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 7/365 24/10654 1.0930665759668158e-5 6.224406890922145e-5 3.298376334496356e-5 7311/1432/6885/5606/7316/7314/6233 7 Murine_coronavirus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 8/365 33/10654 1.1509745924568384e-5 6.48213712784758e-5 3.434950200738743e-5 1147/7311/351/6885/7316/5970/7314/6233 8 Murine_coronavirus R-HSA-9022692 Regulation of MECP2 expression and activity 8/365 33/10654 1.1509745924568384e-5 6.48213712784758e-5 3.434950200738743e-5 818/25942/2290/9611/28996/3066/3065/9612 8 Murine_coronavirus R-HSA-5696395 Formation of Incision Complex in GG-NER 9/365 43/10654 1.1834056113580493e-5 6.628364763071041e-5 3.512437707568326e-5 7311/10401/6117/54778/7316/9978/142/7314/6233 9 Murine_coronavirus R-HSA-9604323 Negative regulation of NOTCH4 signaling 10/365 54/10654 1.2266118067933012e-5 6.83302772806051e-5 3.6208906882456713e-5 8454/6500/7311/4855/7316/9978/207/7314/6233/5717 10 Murine_coronavirus R-HSA-69563 p53-Dependent G1 DNA Damage Response 11/365 66/10654 1.2979509652416956e-5 7.152686770821173e-5 3.7902812567329656e-5 1017/7311/7316/1029/7157/1026/7314/6233/5717/1027/4194 11 Murine_coronavirus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 11/365 66/10654 1.2979509652416956e-5 7.152686770821173e-5 3.7902812567329656e-5 1017/7311/7316/1029/7157/1026/7314/6233/5717/1027/4194 11 Murine_coronavirus R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 6/365 17/10654 1.3939100233635473e-5 7.640415903463294e-5 4.048733870281961e-5 7311/7099/6885/7316/7314/6233 6 Murine_coronavirus R-HSA-1169091 Activation of NF-kappaB in B cells 11/365 67/10654 1.505982346043215e-5 8.210808003693061e-5 4.350990428657889e-5 8454/6500/1147/7311/8945/6885/7316/5970/7314/6233/5717 11 Murine_coronavirus R-HSA-913531 Interferon Signaling 20/365 199/10654 1.5663340498843543e-5 8.494668789055361e-5 4.501411137512263e-5 3665/7311/818/9972/5777/3837/3838/55223/7706/5300/8021/7316/5771/5781/2316/4734/5371/7314/6233/5595 20 Murine_coronavirus R-HSA-5617472 Activation of anterior HOX genes in hindbrain development during early embryogenesis 15/365 122/10654 1.7268577207345632e-5 9.267168396612184e-5 4.9107665136348007e-5 5931/5928/3725/1387/23054/9063/2033/23512/5080/9611/10664/2146/8202/7528/5929 15 Murine_coronavirus R-HSA-5619507 Activation of HOX genes during differentiation 15/365 122/10654 1.7268577207345632e-5 9.267168396612184e-5 4.9107665136348007e-5 5931/5928/3725/1387/23054/9063/2033/23512/5080/9611/10664/2146/8202/7528/5929 15 Murine_coronavirus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 5/365 11/10654 1.7892984599454615e-5 9.50275088831139e-5 5.035604065076947e-5 7311/6885/7316/7314/6233 5 Murine_coronavirus R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 5/365 11/10654 1.7892984599454615e-5 9.50275088831139e-5 5.035604065076947e-5 7311/6885/7316/7314/6233 5 Murine_coronavirus R-HSA-2871837 FCERI mediated NF-kB activation 12/365 82/10654 2.077748142996445e-5 1.0977793023563692e-4 5.8172438512542905e-5 8454/6500/1147/7311/8945/6885/7316/7321/5970/7314/6233/5717 12 Murine_coronavirus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 12/365 83/10654 2.3552346079085187e-5 1.2380079349262726e-4 6.560329596117655e-5 8454/6500/1147/7311/8945/6885/7316/2280/5970/7314/6233/5717 12 Murine_coronavirus R-HSA-5696398 Nucleotide Excision Repair 14/365 111/10654 2.460155743876255e-5 1.2865610395271232e-4 6.817617421268245e-5 10450/7311/10401/60/6117/2033/54778/7316/9978/142/7874/7314/6233/7528 14 Murine_coronavirus R-HSA-3214841 PKMTs methylate histone lysines 11/365 71/10654 2.6543271773501283e-5 1.381058556743087e-4 7.318369348184163e-5 5931/5928/23512/2146/5970/29072/63976/6839/2122/5929/9757 11 Murine_coronavirus R-HSA-5621481 C-type lectin receptors (CLRs) 16/365 142/10654 2.7513617173257388e-5 1.424163830790183e-4 7.546788566754653e-5 8454/6500/1147/7311/5971/8945/1387/4586/6885/2033/7316/7321/5970/7314/6233/5717 16 Murine_coronavirus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 10/365 59/10654 2.7649619739243552e-005 1.424163830790183e-4 7.546788566754653e-5 8454/6500/1147/7311/5971/8945/7316/7314/6233/5717 10 Murine_coronavirus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 6/365 19/10654 2.8829096348739843e-5 1.4701404854456886e-4 7.790423522361749e-5 7311/867/5290/7316/7314/6233 6 Murine_coronavirus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 6/365 19/10654 2.8829096348739843e-5 1.4701404854456886e-4 7.790423522361749e-5 7311/867/5290/7316/7314/6233 6 Murine_coronavirus R-HSA-5610780 Degradation of GLI1 by the proteasome 10/365 60/10654 3.218374576861708e-5 1.6170754614133582e-4 8.569046860994021e-5 8454/6500/7311/8945/7316/9978/83737/7314/6233/5717 10 Murine_coronavirus R-HSA-5610783 Degradation of GLI2 by the proteasome 10/365 60/10654 3.218374576861708e-5 1.6170754614133582e-4 8.569046860994021e-5 8454/6500/7311/2932/8945/7316/9978/7314/6233/5717 10 Murine_coronavirus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 10/365 60/10654 3.218374576861708e-5 1.6170754614133582e-4 8.569046860994021e-5 8454/6500/7311/2932/8945/7316/9978/7314/6233/5717 10 Murine_coronavirus R-HSA-2129379 Molecules associated with elastic fibres 8/365 38/10654 3.48951668213798e-5 1.736288640384189e-4 9.200769586015319e-5 650/655/7040/2335/7042/7043/2192/652 8 Murine_coronavirus R-HSA-5696394 DNA Damage Recognition in GG-NER 8/365 38/10654 3.48951668213798e-5 1.736288640384189e-4 9.200769586015319e-5 7311/60/7316/9978/142/7314/6233/7528 8 Murine_coronavirus R-HSA-177929 Signaling by EGFR 9/365 49/10654 3.5953301051644815e-5 1.780296308112847e-4 9.433970680218016e-5 7311/867/5290/9146/7316/5782/5781/7314/6233 9 Murine_coronavirus R-HSA-5607764 CLEC7A (Dectin-1) signaling 13/365 101/10654 3.853932208898237e-5 1.8991733240964867e-4 1.0063912043479202e-4 8454/6500/1147/7311/5971/8945/6885/7316/7321/5970/7314/6233/5717 13 Murine_coronavirus R-HSA-69275 G2/M Transition 19/365 196/10654 4.2221621904224896e-5 2.0706776292741874e-4 1.0972730749221881e-4 8454/6500/1017/7311/5928/8945/5518/2305/2033/7316/728642/9978/1453/993/7157/1026/7314/6233/5717 19 Murine_coronavirus R-HSA-1227986 Signaling by ERBB2 9/365 50/10654 4.2539592492242714e-5 2.0763372525975612e-4 1.1002721667166537e-4 7311/5290/7316/26469/5782/10273/207/7314/6233 9 Murine_coronavirus R-HSA-5689603 UCH proteinases 13/365 102/10654 4.282487957317226e-5 2.0803555242891736e-4 1.102401489636163e-4 7048/7311/7046/60/7040/7316/51377/9958/4092/7314/6233/5717/7528 13 Murine_coronavirus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 5/365 13/10654 4.708941072807087e-5 2.2767285847298413e-4 1.2064615658234641e-4 7311/7316/207/7314/6233 5 Murine_coronavirus R-HSA-3371556 Cellular response to heat stress 12/365 89/10654 4.798973930340412e-5 2.3093653890135784e-4 1.223756139389994e-4 818/9972/2932/1387/8021/6117/2033/3312/9531/5594/3308/5595 12 Murine_coronavirus R-HSA-453274 Mitotic G2-G2/M phases 19/365 198/10654 4.855306584115619e-5 2.3255557237002384e-4 1.232335561929985e-4 8454/6500/1017/7311/5928/8945/5518/2305/2033/7316/728642/9978/1453/993/7157/1026/7314/6233/5717 19 Murine_coronavirus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 7/365 30/10654 5.3828506026899935e-5 2.538984100528787e-4 1.3454334232327128e-4 1147/7311/6885/7316/55072/7314/6233 7 Murine_coronavirus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 7/365 30/10654 5.3828506026899935e-5 2.538984100528787e-4 1.3454334232327128e-4 7311/8239/7316/7874/7321/7314/6233 7 Murine_coronavirus R-HSA-202403 TCR signaling 14/365 119/10654 5.399985696734396e-5 2.538984100528787e-4 1.3454334232327128e-4 8454/6500/1147/7311/8945/3932/5290/6885/7316/7321/5970/7314/6233/5717 14 Murine_coronavirus R-HSA-69239 Synthesis of DNA 14/365 119/10654 5.399985696734396e-5 2.538984100528787e-4 1.3454334232327128e-4 8454/6500/1017/7311/6117/8881/7316/9978/7321/10393/7314/996/6233/5717 14 Murine_coronavirus R-HSA-383280 Nuclear Receptor transcription pathway 9/365 52/10654 5.880280018839009e-5 2.7521858535662025e-4 1.4584111942902804e-4 367/2908/3164/5468/3172/9611/9612/7421/2099 9 Murine_coronavirus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 25/365 309/10654 5.916458896487e-5 2.7565319858632615e-4 1.4607142538695177e-4 8454/6500/64219/57154/7311/23327/8945/64750/8881/7323/54778/7316/9978/7321/11059/83737/10273/4734/10393/9817/7704/7314/996/6233/5717 25 Murine_coronavirus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 12/365 92/10654 6.688517612373427e-5 3.102140521575911e-4 1.6438557218312398e-4 672/1017/7311/1432/5300/6117/7316/28996/7157/7314/6233/4194 12 Murine_coronavirus R-HSA-182971 EGFR downregulation 7/365 31/10654 6.750303803513156e-5 3.1027181159645675e-4 1.644161794955293e-4 7311/867/9146/7316/5782/7314/6233 7 Murine_coronavirus R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 7/365 31/10654 6.750303803513156e-5 3.1027181159645675e-4 1.644161794955293e-4 2932/5518/1455/857/1499/8312/1855 7 Murine_coronavirus R-HSA-109606 Intrinsic Pathway for Apoptosis 9/365 53/10654 6.872294403978226e-5 3.144688287534679e-4 1.6664022144984795e-4 5599/10018/1029/7027/6774/7157/207/5594/5595 9 Murine_coronavirus R-HSA-912631 Regulation of signaling by CBL 6/365 22/10654 7.265450767689067e-5 3.3098164608361304e-4 1.753905308129852e-4 7311/867/5290/7316/7314/6233 6 Murine_coronavirus R-HSA-983169 Class I MHC mediated antigen processing & presentation 28/365 371/10654 7.357718409611016e-5 3.3370183052439345e-4 1.768319841341073e-4 8454/6500/64219/57154/1147/7311/23327/8945/7099/4615/64750/8881/7323/54778/7316/9978/7321/11059/83737/10273/4734/10393/9817/7704/7314/996/6233/5717 28 Murine_coronavirus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 10/365 66/10654 7.502560148133066e-5 3.3877198906768255e-4 1.7951871256372188e-4 7311/3091/2034/7323/7316/9978/7321/7314/6233/5717 10 Murine_coronavirus R-HSA-1170546 Prolactin receptor signaling 5/365 15/10654 1.0381101478695976e-4 4.586478023992834e-4 2.4304212173353553e-4 8454/6500/8945/9978/5781 5 Murine_coronavirus R-HSA-2691230 Signaling by NOTCH1 HD Domain Mutants in Cancer 5/365 15/10654 1.0381101478695976e-4 4.586478023992834e-4 2.4304212173353553e-4 7311/7316/4851/7314/6233 5 Murine_coronavirus R-HSA-2691232 Constitutive Signaling by NOTCH1 HD Domain Mutants 5/365 15/10654 1.0381101478695976e-4 4.586478023992834e-4 2.4304212173353553e-4 7311/7316/4851/7314/6233 5 Murine_coronavirus R-HSA-937039 IRAK1 recruits IKK complex 5/365 15/10654 1.0381101478695976e-4 4.586478023992834e-4 2.4304212173353553e-4 1147/7311/7316/7314/6233 5 Murine_coronavirus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 5/365 15/10654 1.0381101478695976e-4 4.586478023992834e-4 2.4304212173353553e-4 1147/7311/7316/7314/6233 5 Murine_coronavirus R-HSA-69306 DNA Replication 14/365 127/10654 1.1040582052725282e-4 4.8569084137525386e-4 2.5737250233594965e-4 8454/6500/1017/7311/6117/8881/7316/9978/7321/10393/7314/996/6233/5717 14 Murine_coronavirus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 13/365 112/10654 1.1424907627416896e-4 5.004500135941162e-4 2.6519353737054064e-4 8454/6500/1147/7311/5777/8945/6885/7316/2280/5970/7314/6233/5717 13 Murine_coronavirus R-HSA-452723 Transcriptional regulation of pluripotent stem cells 6/365 24/10654 1.236662371324308e-4 5.371097163590745e-4 2.846198856393144e-4 4089/6997/9314/2034/6774/4087 6 Murine_coronavirus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 6/365 24/10654 1.236662371324308e-4 5.371097163590745e-4 2.846198856393144e-4 2353/2309/207/5594/5595/1027 6 Murine_coronavirus R-HSA-1566948 Elastic fibre formation 8/365 45/10654 1.247427817912429e-4 5.394993727258395e-4 2.8588618878206236e-4 650/655/7040/2335/7042/7043/2192/652 8 Murine_coronavirus R-HSA-5663205 Infectious disease 28/365 383/10654 1.2721465348617243e-4 5.47878234551793e-4 2.903262326354046e-4 6500/1025/7311/23327/9972/8945/867/3932/3837/3838/8812/999/8021/7040/9146/5606/904/7316/1499/6175/9978/905/2547/6124/6122/7314/6233/5717 28 Murine_coronavirus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 11/365 84/10654 1.293309320114469e-4 5.54661946911017e-4 2.9392099060958647e-4 7311/10401/60/6117/54778/7316/9978/142/7314/6233/7528 11 Murine_coronavirus R-HSA-162909 Host Interactions of HIV factors 14/365 129/10654 1.3071061868627517e-4 5.582432673059668e-4 2.958187686057807e-4 6500/1025/7311/9972/8945/3932/3837/8021/904/7316/9978/7314/6233/5717 14 Murine_coronavirus R-HSA-110312 Translesion synthesis by REV1 5/365 16/10654 1.4677679823706097e-4 6.242581667758817e-4 3.3080073330562766e-4 7311/6117/7316/7314/6233 5 Murine_coronavirus R-HSA-8953750 Transcriptional Regulation by E2F6 7/365 35/10654 1.5339199101823615e-4 6.496974826185622e-4 3.4428128475602377e-4 672/5931/5928/4149/23512/7027/2146 7 Murine_coronavirus R-HSA-1643713 Signaling by EGFR in Cancer 6/365 25/10654 1.5806462462274065e-4 6.620393447123413e-4 3.508213626408915e-4 7311/867/5290/7316/7314/6233 6 Murine_coronavirus R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus 6/365 25/10654 1.5806462462274065e-4 6.620393447123413e-4 3.508213626408915e-4 7311/7316/4904/7314/6233/11060 6 Murine_coronavirus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 10/365 72/10654 1.588894427309619e-4 6.620393447123413e-4 3.508213626408915e-4 7311/9184/8881/7316/7321/10393/7314/996/6233/5717 10 Murine_coronavirus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 10/365 72/10654 1.588894427309619e-4 6.620393447123413e-4 3.508213626408915e-4 1017/7311/8881/7316/7321/10393/7314/996/6233/5717 10 Murine_coronavirus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 10/365 73/10654 1.7860283360065385e-4 7.381770340349604e-4 3.9116749634099065e-4 7311/9184/8881/7316/7321/10393/7314/996/6233/5717 10 Murine_coronavirus R-HSA-5654738 Signaling by FGFR2 10/365 73/10654 1.7860283360065385e-4 7.381770340349604e-4 3.9116749634099065e-4 7311/867/5518/5290/7316/5781/5594/7314/6233/5595 10 Murine_coronavirus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 8/365 48/10654 1.9966178157695456e-4 8.219009080979052e-4 4.3553362626805564e-4 7311/5777/867/5290/7316/5781/7314/6233 8 Murine_coronavirus R-HSA-432142 Platelet sensitization by LDL 5/365 17/10654 2.0212583907182173e-4 8.22138829558005e-4 4.3565970326257315e-4 1432/5777/5518/338/5781 5 Murine_coronavirus R-HSA-5655862 Translesion synthesis by POLK 5/365 17/10654 2.0212583907182173e-4 8.22138829558005e-4 4.3565970326257315e-4 7311/6117/7316/7314/6233 5 Murine_coronavirus R-HSA-5656121 Translesion synthesis by POLI 5/365 17/10654 2.0212583907182173e-4 8.22138829558005e-4 4.3565970326257315e-4 7311/6117/7316/7314/6233 5 Murine_coronavirus R-HSA-5689901 Metalloprotease DUBs 7/365 37/10654 2.21399650432226e-4 8.969748683519039e-4 4.7531607914719627e-4 672/8850/7311/2033/7316/7314/6233 7 Murine_coronavirus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 10/365 75/10654 2.2424399789022174e-4 9.049216450294381e-4 4.795271566985264e-4 7311/9184/8881/7316/7321/10393/7314/996/6233/5717 10 Murine_coronavirus R-HSA-74749 Signal attenuation 4/365 10/10654 2.4153707874480893e-4 9.708843361310947e-4 5.144814556545776e-4 3667/3630/5594/5595 4 Murine_coronavirus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 10/365 76/10654 2.5050267583757947e-4 0.0010029892294278085 5.314941641948644e-4 7311/9184/8881/7316/7321/10393/7314/996/6233/5717 10 Murine_coronavirus R-HSA-76002 Platelet activation, signaling and aggregation 21/365 262/10654 2.616307379236961e-4 0.001043468896388282 5.529447502298881e-4 1432/5777/3932/7076/351/5290/7040/7018/2335/7042/5340/5781/1278/2316/207/7043/7422/5594/5595/5054/7410 21 Murine_coronavirus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 9/365 63/10654 2.7147599738143376e-4 0.0010684181060517546 5.66165589445654e-4 7311/8881/7316/7321/10393/7314/996/6233/5717 9 Murine_coronavirus R-HSA-1368082 RORA activates gene expression 5/365 18/10654 2.720557323702517e-4 0.0010684181060517546 5.66165589445654e-4 1387/10499/23054/2033/8648 5 Murine_coronavirus R-HSA-5675482 Regulation of necroptotic cell death 5/365 18/10654 2.720557323702517e-4 0.0010684181060517546 5.66165589445654e-4 7311/8837/7316/7314/6233 5 Murine_coronavirus R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 5/365 18/10654 2.720557323702517e-4 0.0010684181060517546 5.66165589445654e-4 2033/1874/7027/7157/5933 5 Murine_coronavirus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 10/365 77/10654 2.792890154298102e-4 0.0010884838053823401 5.767986070113351e-4 672/1912/9972/9063/8021/6117/142/1029/5371/51588 10 Murine_coronavirus R-HSA-9009391 Extra-nuclear estrogen signaling 10/365 77/10654 2.792890154298102e-4 0.0010884838053823401 5.767986070113351e-4 2353/4318/857/5290/2309/207/2099/5594/5595/1027 10 Murine_coronavirus R-HSA-69205 G1/S-Specific Transcription 6/365 28/10654 3.0824534506098083e-4 0.0011967859041193385 6.341889874460371e-4 5928/1874/1875/7027/3065/5933 6 Murine_coronavirus R-HSA-1912408 Pre-NOTCH Transcription and Translation 11/365 93/10654 3.224800333286173e-4 0.0012473284307993689 6.609719848959942e-4 22938/8850/3725/1387/2033/4855/2648/7027/4851/7157/861 11 Murine_coronavirus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 9/365 65/10654 3.452493236830985e-4 0.0013253953437272507 7.023404337491773e-4 10450/7311/6117/2033/7316/9978/7874/7314/6233 9 Murine_coronavirus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 9/365 65/10654 3.452493236830985e-4 0.0013253953437272507 7.023404337491773e-4 672/1025/2353/3725/8812/1386/904/905/7157 9 Murine_coronavirus R-HSA-110320 Translesion Synthesis by POLH 5/365 19/10654 3.589223880922203e-4 0.0013727442081885293 7.274310772018291e-4 7311/6117/7316/7314/6233 5 Murine_coronavirus R-HSA-5675221 Negative regulation of MAPK pathway 7/365 40/10654 3.670212171282282e-4 0.001398500920284141 7.410798201454343e-4 7311/5518/7316/5594/7314/6233/5595 7 Murine_coronavirus R-HSA-9614399 Regulation of localization of FOXO transcription factors 4/365 11/10654 3.69333703970725e-4 0.0014021001724814559 7.42987100385552e-4 2308/2309/207/4303 4 Murine_coronavirus R-HSA-199418 Negative regulation of the PI3K/AKT network 12/365 110/10654 3.7312206239917885e-4 0.0014112550330596248 7.47838353847257e-4 3932/5518/57761/5290/4615/3667/5781/3630/207/2099/5594/5595 12 Murine_coronavirus R-HSA-6782135 Dual incision in TC-NER 9/365 66/10654 3.879162271886416e-4 0.0014618166649571973 7.746314753457394e-4 10450/7311/6117/2033/7316/9978/7874/7314/6233 9 Murine_coronavirus R-HSA-5696400 Dual Incision in GG-NER 7/365 41/10654 4.297536388686735e-4 0.0016135438821992321 8.550332664593619e-4 7311/6117/7316/9978/142/7314/6233 7 Murine_coronavirus R-HSA-8951664 Neddylation 19/365 234/10654 4.338561733042501e-4 0.0016207514640080342 8.588526371534231e-4 8454/6500/5931/7311/3091/8945/2034/7323/7316/9978/10238/7321/9817/7704/7314/6233/5717/26094/5929 19 Murine_coronavirus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 9/365 67/10654 4.348357586363019e-4 0.0016207514640080342 8.588526371534231e-4 7311/8881/7316/7321/10393/7314/996/6233/5717 9 Murine_coronavirus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 6/365 30/10654 4.585032359863834e-4 0.001685016255620307 8.929072019513e-4 7311/6117/7316/9978/7314/6233 6 Murine_coronavirus R-HSA-525793 Myogenesis 6/365 30/10654 4.585032359863834e-4 0.001685016255620307 8.929072019513e-4 4654/1432/4208/6938/1499/6929 6 Murine_coronavirus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 8/365 54/10654 4.6036458525173374e-4 0.001685016255620307 8.929072019513e-4 10450/7311/2033/7316/9978/7874/7314/6233 8 Murine_coronavirus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 8/365 54/10654 4.6036458525173374e-4 0.001685016255620307 8.929072019513e-4 8454/6500/7311/7316/9978/7314/6233/5717 8 Murine_coronavirus R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 5/365 20/10654 4.6522887838102133e-4 0.001685016255620307 8.929072019513e-4 9184/8881/7321/10393/996 5 Murine_coronavirus R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 5/365 20/10654 4.6522887838102133e-4 0.001685016255620307 8.929072019513e-4 9184/8881/7321/10393/996 5 Murine_coronavirus R-HSA-5213460 RIPK1-mediated regulated necrosis 5/365 20/10654 4.6522887838102133e-4 0.001685016255620307 8.929072019513e-4 7311/8837/7316/7314/6233 5 Murine_coronavirus R-HSA-5218859 Regulated Necrosis 5/365 20/10654 4.6522887838102133e-4 0.001685016255620307 8.929072019513e-4 7311/8837/7316/7314/6233 5 Murine_coronavirus R-HSA-73894 DNA Repair 24/365 334/10654 4.948272866348545e-4 0.0017859083408476265 9.463709410807447e-4 10450/672/1017/7311/3838/10401/7706/60/51567/6117/5599/2033/54778/7316/9978/142/7874/2547/7157/51588/7314/6233/675/7528 24 Murine_coronavirus R-HSA-2426168 Activation of gene expression by SREBF (SREBP) 7/365 42/10654 5.007613258910003e-4 0.001800983715923773 9.543595352160894e-4 1387/10499/23054/4802/6721/8648/6667 7 Murine_coronavirus R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF) 8/365 55/10654 5.229246475118389e-4 0.001867588026827996 9.896538350123193e-4 1387/3837/10499/23054/4802/6721/8648/6667 8 Murine_coronavirus R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 8/365 55/10654 5.229246475118389e-4 0.001867588026827996 9.896538350123193e-4 8454/6500/7311/8945/7316/7314/6233/5717 8 Murine_coronavirus R-HSA-5578768 Physiological factors 4/365 12/10654 5.390938034058194e-4 0.0019116367224091455 0.0010129956855076962 8850/25937/2626/28996 4 Murine_coronavirus R-HSA-5689877 Josephin domain DUBs 4/365 12/10654 5.390938034058194e-4 0.0019116367224091455 0.0010129956855076962 7311/7316/7314/6233 4 Murine_coronavirus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 9/365 69/10654 5.427183280205477e-4 0.0019116367224091455 0.0010129956855076962 9972/2932/8021/6117/3312/9531/5594/3308/5595 9 Murine_coronavirus R-HSA-8948751 Regulation of PTEN stability and activity 9/365 69/10654 5.427183280205477e-4 0.0019116367224091455 0.0010129956855076962 7311/7316/10273/207/4734/7314/6233/11060/5717 9 Murine_coronavirus R-HSA-2122948 Activated NOTCH1 Transmits Signal to the Nucleus 6/365 31/10654 5.523432834946823e-4 0.0019388762519933198 0.0010274301884760492 7311/7316/4851/83737/7314/6233 6 Murine_coronavirus R-HSA-5693532 DNA Double-Strand Break Repair 15/365 166/10654 5.715246778223512e-4 0.001999361074293208 0.0010594817092018439 672/1017/7311/3838/51567/6117/5599/7316/142/2547/7157/51588/7314/6233/675 15 Murine_coronavirus R-HSA-1433557 Signaling by SCF-KIT 7/365 43/10654 5.808089097440077e-4 0.0020180648558901964 0.0010693930327490026 5777/867/3932/4318/5290/5781/6774 7 Murine_coronavirus R-HSA-75893 TNF signaling 7/365 43/10654 5.808089097440077e-4 0.0020180648558901964 0.0010693930327490026 1147/7311/6885/7316/55072/7314/6233 7 Murine_coronavirus R-HSA-210745 Regulation of gene expression in beta cells 5/365 21/10654 5.936134092756951e-4 0.0020555869746877956 0.001089276384019412 2308/5080/3172/3630/207 5 Murine_coronavirus R-HSA-5656169 Termination of translesion DNA synthesis 6/365 32/10654 6.604483446333632e-4 0.0022793250951151423 0.0012078374830083835 7311/7706/6117/7316/7314/6233 6 Murine_coronavirus R-HSA-69541 Stabilization of p53 8/365 57/10654 6.68691373721943e-4 0.0023000290539093677 0.0012188087207365688 7311/7316/1029/7157/7314/6233/5717/4194 8 Murine_coronavirus R-HSA-68949 Orc1 removal from chromatin 9/365 71/10654 6.71617573096673e-4 0.0023023679345287287 0.0012200481172958395 8454/6500/1017/7311/7316/9978/7314/6233/5717 9 Murine_coronavirus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 9/365 72/10654 7.448644488632063e-4 0.0025098607574393144 0.00133000066838376 7311/8881/7316/7321/10393/7314/996/6233/5717 9 Murine_coronavirus R-HSA-198753 ERK/MAPK targets 5/365 22/10654 7.468366156282839e-4 0.0025098607574393144 0.00133000066838376 1432/4208/5518/5594/5595 5 Murine_coronavirus R-HSA-5205685 Pink/Parkin Mediated Mitophagy 5/365 22/10654 7.468366156282839e-4 0.0025098607574393144 0.00133000066838376 7311/7316/8878/7314/6233 5 Murine_coronavirus R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 5/365 22/10654 7.468366156282839e-4 0.0025098607574393144 0.00133000066838376 3725/351/2309/10018/993 5 Murine_coronavirus R-HSA-8863678 Neurodegenerative Diseases 5/365 22/10654 7.468366156282839e-4 0.0025098607574393144 0.00133000066838376 3725/351/2309/10018/993 5 Murine_coronavirus R-HSA-9613829 Chaperone Mediated Autophagy 5/365 22/10654 7.468366156282839e-4 0.0025098607574393144 0.00133000066838376 7311/7316/3312/7314/6233 5 Murine_coronavirus R-HSA-190236 Signaling by FGFR 10/365 87/10654 7.524101030827166e-4 0.0025203279596724987 0.0013355473449971852 7311/867/5518/5290/7316/5781/5594/7314/6233/5595 10 Murine_coronavirus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 11/365 103/10654 7.779736509350758e-4 0.00259746902999496 0.001376425180464595 3932/5518/5290/4615/3667/5781/3630/207/2099/5594/5595 11 Murine_coronavirus R-HSA-5357905 Regulation of TNFR1 signaling 6/365 33/10654 7.84242537534609e-4 0.0026098980551070594 0.0013830114469168089 1147/7311/7316/55072/7314/6233 6 Murine_coronavirus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 10/365 88/10654 8.235885800342168e-4 0.0027319685907283894 0.0014476978616850822 7311/1432/26986/8021/7316/3312/207/7314/6233/5717 10 Murine_coronavirus R-HSA-5687128 MAPK6/MAPK4 signaling 10/365 89/10654 9.002120722451471e-4 0.002976507658229922 0.001577281593475368 2308/7311/3725/2309/7316/8202/4609/7314/6233/5717 10 Murine_coronavirus R-HSA-174490 Membrane binding and targetting of GAG proteins 4/365 14/10654 0.0010323876854022597 0.003348725878282646 0.0017745238030232049 7311/7316/7314/6233 4 Murine_coronavirus R-HSA-174495 Synthesis And Processing Of GAG, GAGPOL Polyproteins 4/365 14/10654 0.0010323876854022597 0.003348725878282646 0.0017745238030232049 7311/7316/7314/6233 4 Murine_coronavirus R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 4/365 14/10654 0.0010323876854022597 0.003348725878282646 0.0017745238030232049 1017/7157/1026/1027 4 Murine_coronavirus R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 4/365 14/10654 0.0010323876854022597 0.003348725878282646 0.0017745238030232049 25942/9611/3065/9612 4 Murine_coronavirus R-HSA-9005895 Pervasive developmental disorders 4/365 14/10654 0.0010323876854022597 0.003348725878282646 0.0017745238030232049 25942/9611/3065/9612 4 Murine_coronavirus R-HSA-918233 TRAF3-dependent IRF activation pathway 4/365 14/10654 0.0010323876854022597 0.003348725878282646 0.0017745238030232049 3665/1387/7706/2033 4 Murine_coronavirus R-HSA-201722 Formation of the beta-catenin:TCF transactivating complex 10/365 91/10654 0.001071048045335406 0.003463167969933095 0.001835167827969681 51176/1387/2033/6597/1499/864/3065/4609/4221/5929 10 Murine_coronavirus R-HSA-114604 GPVI-mediated activation cascade 6/365 35/10654 0.0010848980126630888 0.0034969196949046102 0.0018530532093153054 5777/3932/5290/5781/1278/7410 6 Murine_coronavirus R-HSA-162906 HIV Infection 18/365 233/10654 0.0010896739291514504 0.003501303377367513 0.001855376167108228 6500/1025/7311/23327/9972/8945/3932/3837/8812/8021/904/7316/9978/905/2547/7314/6233/5717 18 Murine_coronavirus R-HSA-204998 Cell death signalling via NRAGE, NRIF and NADE 9/365 76/10654 0.0011058450921483131 0.0035421600607875654 0.0018770265379885844 7311/26574/5599/7316/10018/8878/7314/6233/7410 9 Murine_coronavirus R-HSA-69620 Cell Cycle Checkpoints 21/365 293/10654 0.001135614644144147 0.0036261838325475095 0.0019215515867466136 672/1017/7311/9184/5518/6117/8881/7316/1029/993/7321/7157/1026/10393/51588/7314/996/6233/5717/1027/4194 21 Murine_coronavirus R-HSA-982772 Growth hormone receptor signaling 5/365 24/10654 0.0011393741788601902 0.0036268898550673757 0.0019219257152398106 5777/3667/6774/5594/5595 5 Murine_coronavirus R-HSA-73893 DNA Damage Bypass 7/365 48/10654 0.001145998963455375 0.0036366840171571497 0.0019271157410558043 7311/7706/6117/7316/9978/7314/6233 7 Murine_coronavirus R-HSA-5683057 MAPK family signaling cascades 21/365 294/10654 0.0011853477092999669 0.003749942598865636 0.0019871326120818157 2308/7311/818/3725/5518/6711/60/3667/2335/2309/7316/9978/5781/8202/10048/5594/4609/7314/6233/5595/5717 21 Murine_coronavirus R-HSA-5693606 DNA Double Strand Break Response 9/365 77/10654 0.0012152422199492895 0.0038326870013785284 0.002030979710101485 672/7311/3838/5599/7316/7157/51588/7314/6233 9 Murine_coronavirus R-HSA-1912422 Pre-NOTCH Expression and Processing 11/365 109/10654 0.0012470887854795951 0.003921061365388298 0.0020778101818129517 22938/8850/3725/1387/2033/4855/2648/7027/4851/7157/861 11 Murine_coronavirus R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 4/365 15/10654 0.0013700519292623703 0.0042045006811195496 0.0022280075496356228 7311/7316/7314/6233 4 Murine_coronavirus R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 4/365 15/10654 0.0013700519292623703 0.0042045006811195496 0.0022280075496356228 2932/5518/1499/8312 4 Murine_coronavirus R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 4/365 15/10654 0.0013700519292623703 0.0042045006811195496 0.0022280075496356228 2932/5518/1499/8312 4 Murine_coronavirus R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 4/365 15/10654 0.0013700519292623703 0.0042045006811195496 0.0022280075496356228 2932/5518/1499/8312 4 Murine_coronavirus R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 4/365 15/10654 0.0013700519292623703 0.0042045006811195496 0.0022280075496356228 2932/5518/1499/8312 4 Murine_coronavirus R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 4/365 15/10654 0.0013700519292623703 0.0042045006811195496 0.0022280075496356228 2932/5518/1499/8312 4 Murine_coronavirus R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 4/365 15/10654 0.0013700519292623703 0.0042045006811195496 0.0022280075496356228 2932/5518/1499/8312 4 Murine_coronavirus R-HSA-8866910 TFAP2 (AP-2) family regulates transcription of growth factors and their receptors 4/365 15/10654 0.0013700519292623703 0.0042045006811195496 0.0022280075496356228 7021/7422/2099/7528 4 Murine_coronavirus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 5/365 25/10654 0.0013847015674195529 0.0042241640077531 0.0022384273458286004 1432/4208/5518/5594/5595 5 Murine_coronavirus R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 5/365 25/10654 0.0013847015674195529 0.0042241640077531 0.0022384273458286004 7311/6117/7316/7314/6233 5 Murine_coronavirus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 9/365 79/10654 0.0014602435438247866 0.004441393568013075 0.0023535394927802276 10450/7311/6117/2033/7316/9978/7874/7314/6233 9 Murine_minute_virus R-HSA-69620 Cell Cycle Checkpoints 194/2393 293/10654 2.497155277364092e-59 3.3461880716678833e-56 1.761151616667307e-56 1017/220134/4172/6118/5905/55839/80010/11130/4928/79682/5684/5903/10403/83990/54908/8318/6249/55143/9156/246184/55055/5883/25936/5525/9735/1763/7531/51512/1029/80776/1783/1058/7486/7321/5707/991/401541/79019/5526/10111/7532/8317/10971/348235/80152/8697/9212/1063/51588/51720/8379/1027/3619/5982/63967/79172/7533/2810/147841/348995/23421/4173/11200/545/55920/79023/9133/472/57122/5705/79980/64105/10197/7336/6232/7534/332/580/1780/11073/29086/23122/5528/5048/1781/7316/891/993/5695/5501/116028/890/57405/8655/4085/983/100527963/84515/641/5714/4171/23279/55166/51433/79902/4194/3796/54821/9656/5519/9088/6119/9183/3364/81565/7341/5701/10524/2491/4683/1062/699/10926/144715/5708/22919/5985/5686/990/1060/91687/995/165918/79003/11243/84126/5529/51143/1111/7157/8900/51529/5984/7324/83540/64682/29945/10393/8924/11004/6233/5527/51434/701/672/7514/5932/7158/7311/9184/9025/79184/5518/54820/5347/57551/7156/84643/5983/6117/6396/7334/5001/23332/7465/25909/51230/64946/9793/10726/5884/5810/81930/55746/140735/83695/4176/7529/7314/996/4193/5515/1778/5516 194 Murine_minute_virus R-HSA-168254 Influenza Infection 129/2393 155/10654 6.460106796003133e-59 4.328271553322099e-56 2.27803765964321e-56 3839/6158/23165/3303/6138/4928/6144/2963/3837/3838/6203/5434/5440/5903/4736/2926/6206/6194/6191/6166/6128/6132/9631/6147/6129/6217/3843/5430/6222/5436/6176/6152/6136/8106/6125/821/811/6224/348995/6146/6154/6141/9636/6202/79023/57122/5441/23636/6232/5438/6134/6169/5431/6160/23511/6164/5435/6155/6175/293/5433/6218/5611/6209/6193/23279/4927/6210/6229/6231/11224/6205/6165/79902/6130/2962/6142/10898/3840/6167/6204/9883/6228/5437/23521/23225/3320/6156/6235/6143/6181/5439/6124/5901/6207/8086/3836/6139/6233/7514/7311/6223/25873/9972/1213/5610/1211/3921/6188/6189/8021/7040/6396/6135/6201/6161/3304/9045/6187/5432/55746/6168/6208/6157/6137/8480/6122/6133/6230 129 Murine_minute_virus R-HSA-68877 Mitotic Prometaphase 151/2393 200/10654 3.340092156518133e-58 1.491907829911433e-55 7.852146473218067e-56 10844/115106/220134/5905/55839/11130/22995/84617/4928/55559/79682/5903/10403/54908/6249/55143/22981/55055/25936/5525/9735/7531/80776/1459/1783/1058/11190/991/401541/203068/79019/5526/54801/7532/1454/348235/80152/10382/9212/1063/347688/8379/95681/3619/79172/10274/121441/1460/147841/23244/7277/348995/23421/79441/55920/79023/9133/10381/57122/79980/64105/10735/6232/332/23047/1780/10051/23122/5885/5528/5048/1781/23354/891/5501/57405/8655/4085/9738/1457/983/1639/100527963/55722/4957/23279/55166/79902/5566/3796/54821/5519/84131/9183/81565/2491/1062/699/7840/7283/347733/3320/22919/80097/1060/91687/79003/8243/9126/11243/10376/10426/23397/5529/51143/9918/1069/83540/11004/5577/5527/80254/701/7514/9184/54930/5518/10383/54820/5347/113130/57551/84643/6396/9662/55142/23332/1453/25909/64946/9793/10726/81930/55746/8481/140735/93323/7280/5515/1778/5516 151 Murine_minute_virus R-HSA-5663205 Infectious disease 227/2393 383/10654 1.7131329651897342e-56 5.73899543338561e-54 3.0205239123082156e-54 3839/6158/6884/23165/137492/3303/5905/6138/8945/1173/4928/6144/2963/3837/3838/2237/6917/6203/5434/5440/164/5684/5903/8065/4736/2926/902/6206/6194/6191/162/6166/6128/5606/6132/9631/1499/5604/1938/6147/6129/25978/6217/51160/3843/5707/5430/27243/6222/5436/6176/6152/6136/2060/1174/7518/7520/8106/6125/4869/821/6500/404672/84168/6749/811/6224/348995/6146/6154/6141/9636/6202/79023/57122/5705/5441/23636/10197/91782/6232/160/5438/6134/3981/3978/6169/5431/6160/7469/23511/6164/79720/5435/4686/7316/6155/1500/6175/293/5433/6218/5695/6872/5611/292/567/4331/6209/51271/5714/6193/6714/23279/4927/6210/5605/6229/6231/11224/6205/8148/2966/6165/79902/6130/9150/2962/6142/10898/3840/6167/6204/23327/9883/5701/867/6228/5437/8812/23521/8732/23225/999/5708/3320/2965/5686/6156/27183/6235/905/6143/2068/6181/5439/6124/2071/5902/5901/6207/8086/5478/6873/3836/6139/6827/5609/6233/2885/3326/2968/7514/163/1025/7311/6223/25873/9972/2967/1213/93343/5610/1211/3921/6188/6189/8021/7040/7251/8905/11198/6396/6135/6201/904/6161/6883/7936/3304/6829/1104/51497/2547/9045/2961/6187/6416/1022/5432/55746/6168/22916/6208/10254/6157/6137/8907/8178/8480/92421/6122/6133/7296/7314/25920/6230 227 Murine_minute_virus R-HSA-168255 Influenza Life Cycle 120/2393 144/10654 5.7518861519182955e-55 1.5415054887141032e-52 8.113186782705807e-53 6158/23165/3303/6138/4928/6144/2963/3837/6203/5434/5440/5903/4736/2926/6206/6194/6191/6166/6128/6132/9631/6147/6129/6217/3843/5430/6222/5436/6176/6152/6136/6125/821/811/6224/348995/6146/6154/6141/6202/79023/57122/5441/23636/6232/5438/6134/6169/5431/6160/23511/6164/5435/6155/6175/5433/6218/5611/6209/6193/23279/4927/6210/6229/6231/11224/6205/6165/79902/6130/2962/6142/6167/6204/9883/6228/5437/23521/23225/3320/6156/6235/6143/6181/5439/6124/5901/6207/8086/3836/6139/6233/7514/7311/6223/25873/9972/1213/1211/3921/6188/6189/8021/6396/6135/6201/6161/3304/9045/6187/5432/55746/6168/6208/6157/6137/8480/6122/6133/6230 120 Murine_minute_virus R-HSA-2500257 Resolution of Sister Chromatid Cohesion 110/2393 126/10654 9.372174812189103e-55 2.0931190413888998e-52 1.1016416007309998e-52 220134/5905/55839/11130/84617/4928/79682/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/401541/79019/5526/348235/80152/10382/9212/1063/347688/8379/3619/79172/10274/147841/23244/7277/348995/23421/55920/79023/9133/10381/57122/79980/64105/10735/6232/332/23047/1780/23122/5885/5528/5048/1781/891/5501/57405/8655/4085/983/100527963/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/347733/22919/1060/91687/79003/8243/9126/11243/10376/5529/51143/83540/11004/5527/701/7514/9184/5518/10383/54820/5347/113130/57551/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/7280/5515/1778/5516 110 Murine_minute_virus R-HSA-69618 Mitotic Spindle Checkpoint 101/2393 112/10654 2.1580911737705147e-53 4.131203104074985e-51 2.1743174231973603e-51 220134/5905/55839/11130/4928/79682/5903/10403/54908/6249/55143/246184/55055/25936/5525/9735/80776/1783/1058/7321/991/401541/79019/5526/348235/80152/8697/9212/1063/8379/3619/79172/147841/348995/23421/55920/79023/57122/79980/64105/6232/332/1780/23122/5528/5048/1781/5501/57405/8655/4085/100527963/23279/55166/51433/79902/3796/54821/5519/9183/81565/2491/1062/699/22919/1060/91687/79003/11243/5529/51143/51529/7324/83540/64682/29945/10393/11004/5527/51434/701/7514/9184/5518/54820/5347/57551/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/996/5515/1778/5516 101 Murine_minute_virus R-HSA-141424 Amplification of signal from the kinetochores 90/2393 96/10654 2.4576769828277634e-51 3.659207952210225e-49 1.9258989222159084e-49 220134/5905/55839/11130/4928/79682/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/401541/79019/5526/348235/80152/9212/1063/8379/3619/79172/147841/348995/23421/55920/79023/57122/79980/64105/6232/332/1780/23122/5528/5048/1781/5501/57405/8655/4085/100527963/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/22919/1060/91687/79003/11243/5529/51143/83540/11004/5527/701/7514/9184/5518/54820/5347/57551/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/5515/1778/5516 90 Murine_minute_virus R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 90/2393 96/10654 2.4576769828277634e-51 3.659207952210225e-49 1.9258989222159084e-49 220134/5905/55839/11130/4928/79682/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/401541/79019/5526/348235/80152/9212/1063/8379/3619/79172/147841/348995/23421/55920/79023/57122/79980/64105/6232/332/1780/23122/5528/5048/1781/5501/57405/8655/4085/100527963/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/22919/1060/91687/79003/11243/5529/51143/83540/11004/5527/701/7514/9184/5518/54820/5347/57551/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/5515/1778/5516 90 Murine_minute_virus R-HSA-73894 DNA Repair 198/2393 334/10654 3.079005545576292e-49 4.1258674310722313e-47 2.171509174248543e-47 9318/8467/11284/51750/1017/7014/6118/80010/54962/25/3838/2237/6917/5434/5440/5893/4436/83990/151987/902/7516/5888/5892/9156/5883/1763/322/328/27339/7486/5430/10111/57804/56852/5436/51588/7518/10445/7520/51720/675/2956/7515/5982/63967/404672/54107/7013/5531/51548/4292/9636/11200/545/472/6613/5441/7507/7706/80198/7336/23583/5438/3981/3978/580/5431/11073/2072/5591/29086/5435/7316/2140/5433/11201/116028/2070/890/197342/9031/6996/4331/5425/641/5111/56655/5426/9100/10635/10459/2966/7415/5395/7517/64421/9656/6119/84464/51455/3364/22976/29844/7341/10524/4683/5437/51008/5427/144715/1161/5889/55775/9937/2177/1642/5429/2965/5985/65057/2033/165918/84126/142/8914/7398/2068/54890/5439/1111/10987/2071/7157/9682/55215/8900/5984/23514/1069/7329/9246/79728/8924/57599/6233/2067/51426/2968/672/146956/2138/5932/7158/7311/6047/9025/2189/7318/2967/79184/23030/5536/7156/8607/5890/5887/5983/6117/5599/7334/10973/5981/10038/3980/10714/7874/2547/55666/54386/5884/5810/5424/79840/1022/5432/2139/348654/91603/8178/83695/5886/4437/55183/57697/7508/7314/8451/7528 198 Murine_minute_virus R-HSA-168273 Influenza Viral RNA Transcription and Replication 110/2393 134/10654 3.8340118569722e-49 4.670523534857043e-47 2.4581702815037073e-47 6158/23165/6138/4928/6144/2963/6203/5434/5440/5903/4736/2926/6206/6194/6191/6166/6128/6132/9631/6147/6129/6217/3843/5430/6222/5436/6176/6152/6136/6125/6224/348995/6146/6154/6141/6202/79023/57122/5441/23636/6232/5438/6134/6169/5431/6160/23511/6164/5435/6155/6175/5433/6218/5611/6209/6193/23279/4927/6210/6229/6231/11224/6205/6165/79902/6130/2962/6142/6167/6204/9883/6228/5437/23521/23225/3320/6156/6235/6143/6181/5439/6124/6207/8086/6139/6233/7311/6223/25873/9972/3921/6188/6189/8021/6396/6135/6201/6161/9045/6187/5432/55746/6168/6208/6157/6137/8480/6122/6133/6230 110 Murine_minute_virus R-HSA-5663220 RHO GTPases Activate Formins 110/2393 140/10654 1.417858757525578e-45 1.5832756125702287e-43 8.333029539843308e-44 220134/5905/55839/11130/84617/4928/79682/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/1856/401541/79019/5526/348235/80152/10382/9212/1063/347688/8379/3619/79172/147841/7277/348995/23421/55920/79023/10381/57122/79980/64105/6232/332/1780/23122/5528/5048/1781/5501/57405/8655/4085/5216/100527963/81624/6714/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/347733/51466/22919/1060/91687/79003/11243/10376/5529/51143/998/83540/11004/1855/5527/701/1857/7514/9184/5518/10383/54820/29984/5347/1729/57551/84643/5217/6396/23332/25909/64946/9793/10726/81930/55746/140735/7280/5515/1778/5516 110 Murine_minute_virus R-HSA-68882 Mitotic Anaphase 138/2393 201/10654 4.2636229940815815e-45 4.394811393899476e-43 2.3130586283681452e-43 4000/220134/5905/55839/11130/84617/4928/79682/5684/5903/10403/54908/6249/55143/246184/55055/25936/5525/9735/80776/1783/1058/7321/5707/991/401541/79019/5526/348235/80152/8697/10382/9212/1063/347688/8379/3619/79172/10274/147841/23244/7277/348995/23421/55920/79023/10381/57122/5705/79980/64105/10735/10197/6232/332/7443/23047/1780/23141/23122/5885/5528/5048/1781/7316/5695/5501/57405/8655/4085/100527963/5714/23279/55166/51433/79902/3796/54821/5519/9183/81565/5701/2491/1062/699/347733/5708/22919/5686/1060/91687/79003/8243/9126/11243/10376/5529/51143/5520/51529/7324/83540/64682/29945/10393/11004/9232/23592/6233/9700/5527/51434/701/7514/7311/9184/5518/10383/54820/5347/113130/57551/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/7280/7314/996/5515/1778/5516 138 Murine_minute_virus R-HSA-2467813 Separation of Sister Chromatids 133/2393 190/10654 5.387398766850532e-45 5.156510248271223e-43 2.7139527622480125e-43 220134/5905/55839/11130/84617/4928/79682/5684/5903/10403/54908/6249/55143/246184/55055/25936/5525/9735/80776/1783/1058/7321/5707/991/401541/79019/5526/348235/80152/8697/10382/9212/1063/347688/8379/3619/79172/10274/147841/23244/7277/348995/23421/55920/79023/10381/57122/5705/79980/64105/10735/10197/6232/332/23047/1780/23122/5885/5528/5048/1781/7316/5695/5501/57405/8655/4085/100527963/5714/23279/55166/51433/79902/3796/54821/5519/9183/81565/5701/2491/1062/699/347733/5708/22919/5686/1060/91687/79003/8243/9126/11243/10376/5529/51143/51529/7324/83540/64682/29945/10393/11004/9232/6233/9700/5527/51434/701/7514/7311/9184/5518/10383/54820/5347/113130/57551/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/7280/7314/996/5515/1778/5516 133 Murine_minute_virus R-HSA-2555396 Mitotic Metaphase and Anaphase 138/2393 202/10654 1.0577969955797754e-44 9.44965316051266e-43 4.973501663427715e-43 4000/220134/5905/55839/11130/84617/4928/79682/5684/5903/10403/54908/6249/55143/246184/55055/25936/5525/9735/80776/1783/1058/7321/5707/991/401541/79019/5526/348235/80152/8697/10382/9212/1063/347688/8379/3619/79172/10274/147841/23244/7277/348995/23421/55920/79023/10381/57122/5705/79980/64105/10735/10197/6232/332/7443/23047/1780/23141/23122/5885/5528/5048/1781/7316/5695/5501/57405/8655/4085/100527963/5714/23279/55166/51433/79902/3796/54821/5519/9183/81565/5701/2491/1062/699/347733/5708/22919/5686/1060/91687/79003/8243/9126/11243/10376/5529/51143/5520/51529/7324/83540/64682/29945/10393/11004/9232/23592/6233/9700/5527/51434/701/7514/7311/9184/5518/10383/54820/5347/113130/57551/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/7280/7314/996/5515/1778/5516 138 Murine_minute_virus R-HSA-5693532 DNA Double-Strand Break Repair 121/2393 166/10654 5.434514134653612e-44 4.5514055877724e-42 2.3954766251433682e-42 8467/51750/1017/6118/80010/54962/25/3838/2237/5893/83990/151987/7516/5888/5892/9156/5883/1763/322/7486/10111/57804/51588/7518/7520/51720/675/7515/5982/63967/54107/5531/51548/11200/545/472/6613/80198/7336/3981/580/11073/2072/5591/29086/7316/2140/116028/2070/890/197342/9031/5425/641/5111/56655/5426/10635/7517/64421/9656/6119/84464/3364/22976/7341/10524/4683/5427/144715/5889/55775/5429/5985/165918/84126/142/8914/1111/7157/9682/8900/5984/23514/7329/79728/8924/6233/2067/51426/672/146956/2138/5932/7158/7311/6047/9025/79184/23030/5536/7156/5890/5983/6117/5599/7334/5981/10038/3980/10714/2547/5884/5810/5424/79840/2139/348654/83695/55183/7314 121 Murine_minute_virus R-HSA-3700989 Transcriptional Regulation by TP53 201/2393 365/10654 3.8607041609240455e-43 2.921501867706549e-41 1.5376325619508151e-41 23368/6884/1017/23774/6118/5170/80010/27161/9891/2963/6917/5434/5440/4436/83990/8621/902/5892/9156/5883/1763/7531/7027/1029/1459/7486/6446/5430/10111/8445/7532/207/10971/5436/9212/57690/4849/1027/4869/5982/7249/404672/58528/4850/7533/2810/55367/1460/6749/4292/11200/545/472/117584/5441/54971/7534/332/5438/580/5431/7469/11073/7001/5435/64065/7316/5433/1869/891/6872/28996/116028/890/80196/2539/84289/1457/4331/10769/983/6790/641/5111/1108/8148/2966/8797/5395/64223/4194/9150/2962/9656/5519/6119/147923/1647/5928/3364/1432/10524/10848/1387/4683/4848/5437/8812/144715/57459/23019/1616/9099/843/2177/6794/2965/5985/54815/51755/2033/995/1874/10128/84126/5728/6009/900/905/2068/5439/1111/192669/3066/3065/2071/7157/1107/55215/8900/5984/91875/6873/6827/5371/1337/6233/5527/79109/2968/2475/672/55571/1025/5932/7311/7161/2967/5518/1386/5325/7156/581/5983/6117/11198/50484/904/9167/6883/3276/7936/85456/6829/29883/26523/51497/7874/51230/5052/637/1020/5884/5810/10397/1022/8795/5432/57521/26155/8178/83695/7529/7296/7314/253260/4193/5515/25920/1263/5516 201 Murine_minute_virus R-HSA-68886 M Phase 212/2393 395/10654 3.92440549393417e-43 2.921501867706549e-41 1.5376325619508151e-41 10844/4000/115106/23165/220134/5905/55839/11130/22995/84617/4928/55559/79682/5684/5903/10403/54908/6249/55143/22981/9631/246184/55055/25936/5525/9735/7531/80776/1459/1783/1058/11190/7321/5707/991/91754/401541/203068/79019/5526/54801/7532/5862/1454/348235/2801/80152/8697/10382/5578/9212/5594/1063/347688/8379/95681/3619/140609/79172/10274/121441/1460/147841/23244/7277/348995/23421/79441/55920/79023/9133/10381/57122/5705/23636/79980/64105/10735/25836/10197/6232/332/7443/23047/1780/23141/10051/23122/5885/23511/5528/5048/1781/23354/7316/10776/891/5695/5501/26003/57405/8655/4085/9738/1457/983/1639/100527963/8548/5714/55722/4957/23279/4927/55166/51433/79902/5566/3796/54821/5519/84131/9183/9883/81565/5701/2491/10112/1062/699/23225/7840/7283/347733/5708/3320/22919/5686/80097/1060/91687/79003/8243/9126/11243/10376/10426/23397/5529/51143/9918/5520/51529/1069/8086/7324/83540/64900/64682/29945/10393/23399/79648/11004/9232/23592/5577/6233/9700/23175/5527/23133/51434/80254/701/7514/7311/9184/54930/9972/5518/10383/54820/5347/113130/57551/8021/84643/6396/9662/55142/23332/1453/25909/64689/64946/9793/10726/6418/81930/55746/8481/140735/93323/7280/8480/7314/996/5595/5515/1778/5516 212 Murine_minute_virus R-HSA-72613 Eukaryotic Translation Initiation 95/2393 119/10654 1.4339522740393688e-40 9.607480236063771e-39 5.0565685452967215e-39 6158/6138/6144/6203/4736/6206/8891/6194/1965/6191/6166/6128/6132/6147/6129/6217/6222/1983/6176/6152/6136/8667/6125/6224/6146/6154/6141/10480/26986/6202/6232/1967/6134/6169/6160/6164/6155/6175/6218/9669/6209/6193/6210/6229/6231/11224/6205/6165/6130/8890/6142/6167/6204/8663/6228/23521/8894/1981/6156/6235/6143/1973/6181/6124/6207/1977/6139/8893/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/6135/6201/1978/6161/9045/6187/6168/6208/6157/6137/8892/1974/6122/6133/1968/6230 95 Murine_minute_virus R-HSA-72737 Cap-dependent Translation Initiation 95/2393 119/10654 1.4339522740393688e-40 9.607480236063771e-39 5.0565685452967215e-39 6158/6138/6144/6203/4736/6206/8891/6194/1965/6191/6166/6128/6132/6147/6129/6217/6222/1983/6176/6152/6136/8667/6125/6224/6146/6154/6141/10480/26986/6202/6232/1967/6134/6169/6160/6164/6155/6175/6218/9669/6209/6193/6210/6229/6231/11224/6205/6165/6130/8890/6142/6167/6204/8663/6228/23521/8894/1981/6156/6235/6143/1973/6181/6124/6207/1977/6139/8893/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/6135/6201/1978/6161/9045/6187/6168/6208/6157/6137/8892/1974/6122/6133/1968/6230 95 Murine_minute_virus R-HSA-927802 Nonsense-Mediated Decay (NMD) 91/2393 115/10654 2.5392721483014397e-38 1.5466475812381497e-36 8.140250427569209e-37 10921/6158/9887/6138/6144/6203/4736/6206/6194/2107/6191/6166/6128/6132/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/6154/6141/26986/6202/6232/26019/2935/6134/6169/6160/22794/6164/4686/6155/6175/6218/65109/6209/6193/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/55802/1981/6156/6235/6143/6181/6124/5520/6207/6139/6233/7311/6223/25873/5518/3921/6188/6189/23293/9775/6135/6201/6161/9045/5976/6187/65110/6168/22916/6208/6157/6137/6122/6133/5515/6230 91 Murine_minute_virus R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 91/2393 115/10654 2.5392721483014397e-38 1.5466475812381497e-36 8.140250427569209e-37 10921/6158/9887/6138/6144/6203/4736/6206/6194/2107/6191/6166/6128/6132/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/6154/6141/26986/6202/6232/26019/2935/6134/6169/6160/22794/6164/4686/6155/6175/6218/65109/6209/6193/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/55802/1981/6156/6235/6143/6181/6124/5520/6207/6139/6233/7311/6223/25873/5518/3921/6188/6189/23293/9775/6135/6201/6161/9045/5976/6187/65110/6168/22916/6208/6157/6137/6122/6133/5515/6230 91 Murine_minute_virus R-HSA-5685942 HDR through Homologous Recombination (HRR) 64/2393 67/10654 3.6908717848493847e-38 2.150333996390511e-36 1.1317547349423742e-36 51750/6118/80010/83990/7516/5888/5892/9156/5883/1763/7486/10111/57804/675/5982/54107/545/472/80198/580/11073/7316/116028/197342/5425/641/5111/56655/5426/10635/7517/6119/84464/3364/10524/4683/5427/144715/5889/5429/5985/84126/1111/5984/23514/79728/6233/51426/672/146956/5932/7311/7156/5890/5983/6117/5981/10714/5884/5810/5424/348654/83695/7314 64 Murine_minute_virus R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 88/2393 112/10654 1.1997400161600868e-36 6.698548423560485e-35 3.5255518018739393e-35 6158/6138/6144/6203/4736/6206/6194/1965/6191/6166/6128/6132/6147/6129/6217/6222/1983/6176/6152/6136/8667/6125/6224/6146/6154/6141/10480/6202/6232/6134/6169/6160/6164/6155/6175/6218/9669/6209/6193/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/8663/6228/23521/8894/1981/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/1974/6122/6133/1968/6230 88 Murine_minute_virus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 79/2393 95/10654 2.360301394872015e-36 1.2651215476514e-34 6.658534461323157e-35 6158/6138/6144/6203/4736/6206/6194/2107/6191/6166/6128/6132/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/6154/6141/26986/6202/6232/2935/6134/6169/6160/6164/4686/6155/6175/6218/6209/6193/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/1981/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/5976/6187/6168/22916/6208/6157/6137/6122/6133/6230 79 Murine_minute_virus R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 87/2393 111/10654 4.313909188813506e-36 2.223322428080807e-34 1.1701696989898983e-34 6158/6138/6144/6203/4736/6206/6194/1965/6191/6166/6128/6132/6147/6129/6217/6222/6176/6152/6136/8667/6125/6224/6146/6154/6141/10480/26986/6202/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/8663/6228/23521/8894/1981/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/1974/6122/6133/1968/6230 87 Murine_minute_virus R-HSA-913531 Interferon Signaling 126/2393 199/10654 1.1889260583800405e-35 5.900595993441682e-34 3.105576838653517e-34 3839/3135/23165/3665/3120/3460/4928/3837/3838/5903/6737/51447/10379/5335/115362/960/9631/7412/3117/3107/3119/10410/4502/2633/9021/85363/9830/4600/3123/163351/23650/348995/9636/2209/79023/317649/3383/57122/23636/8638/25820/1982/7706/2634/3113/3662/3115/9470/23511/4684/7316/3122/3394/2317/3663/115361/3664/567/103/4734/3434/6672/6772/8651/23279/4927/3659/3106/79902/23586/8672/3840/25939/9883/4939/388646/7341/6059/10437/23225/2635/1981/1973/3454/3661/8086/7324/3836/9246/1977/5371/51191/4599/6233/684/3716/7311/81603/9972/10107/3133/7318/5610/3134/8021/9775/3127/4940/6396/3437/7334/7726/3456/6773/4938/4261/5781/55746/3105/3660/5495/5724/1974/8480/7314/5595 126 Murine_minute_virus R-HSA-156842 Eukaryotic Translation Elongation 77/2393 93/10654 3.3930932680312713e-035 1.6238374925578225e-33 8.54651311872538e-34 6158/6138/6144/6203/4736/6206/6194/6191/6166/6128/6132/1917/1938/6147/6129/1915/6217/1936/6222/6176/6152/6136/6125/1937/6224/6146/6154/6141/6202/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133/6230 77 Murine_minute_virus R-HSA-156902 Peptide chain elongation 74/2393 89/10654 4.116618460824737e-34 1.8387562458350493e-32 9.677664451763418e-33 6158/6138/6144/6203/4736/6206/6194/6191/6166/6128/6132/1938/6147/6129/1915/6217/6222/6176/6152/6136/6125/6224/6146/6154/6141/6202/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133/6230 74 Murine_minute_virus R-HSA-192823 Viral mRNA Translation 74/2393 89/10654 4.116618460824737e-34 1.8387562458350493e-32 9.677664451763418e-33 6158/6138/6144/6203/4736/2926/6206/6194/6191/6166/6128/6132/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/6154/6141/6202/6232/6134/6169/6160/6164/6155/6175/6218/5611/6209/6193/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133/6230 74 Murine_minute_virus R-HSA-5693538 Homology Directed Repair 97/2393 138/10654 2.7062169760471503e-33 1.1697841122268327e-31 6.156758485404383e-32 51750/1017/6118/80010/54962/25/2237/5893/83990/151987/7516/5888/5892/9156/5883/1763/7486/10111/57804/51588/51720/675/7515/5982/63967/54107/5531/51548/545/472/6613/80198/7336/580/11073/2072/29086/7316/116028/890/197342/5425/641/5111/56655/5426/10635/7517/9656/6119/84464/3364/7341/10524/4683/5427/144715/5889/5429/5985/165918/84126/142/8914/1111/8900/5984/23514/7329/79728/8924/6233/2067/51426/672/146956/5932/7158/7311/6047/9025/79184/7156/5890/5983/6117/7334/5981/10038/3980/10714/5884/5810/5424/348654/83695/7314 97 Murine_minute_virus R-HSA-72689 Formation of a pool of free 40S subunits 78/2393 101/10654 1.1413147807176317e-31 4.607659274658095e-30 2.4250838287674187e-30 6158/6138/6144/6203/4736/6206/6194/6191/6166/6128/6132/6147/6129/6217/6222/6176/6152/6136/8667/6125/6224/6146/6154/6141/10480/6202/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/8663/6228/23521/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/8664/3646/51386/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133/6230 78 Murine_minute_virus R-HSA-2408557 Selenocysteine synthesis 74/2393 93/10654 1.169107577152054e-31 4.607659274658095e-30 2.4250838287674187e-30 6158/6138/6144/6203/4736/6206/6194/6191/6166/6128/6132/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/6154/6141/6202/6232/6134/6169/6160/6164/6155/6175/6218/79048/6209/6193/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/6156/6235/6143/6181/6124/6207/6139/6233/51091/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133/6230 74 Murine_minute_virus R-HSA-72764 Eukaryotic Translation Termination 74/2393 93/10654 1.169107577152054e-31 4.607659274658095e-30 2.4250838287674187e-30 6158/6138/6144/6203/4736/6206/6194/2107/6191/6166/6128/6132/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/6154/6141/6202/6232/2935/6134/6169/6160/6164/6155/6175/6218/6209/6193/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133/6230 74 Murine_minute_virus R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 92/2393 132/10654 3.57401903535069e-31 1.368338716391407e-29 7.20178271784951e-30 51750/1017/6118/80010/54962/25/5893/83990/151987/7516/5888/5892/9156/5883/1763/7486/10111/57804/51588/51720/675/5982/63967/54107/5531/51548/545/472/6613/80198/7336/580/11073/2072/29086/7316/116028/890/197342/5425/641/5111/56655/5426/10635/7517/9656/6119/84464/3364/7341/10524/4683/5427/144715/5889/5429/5985/165918/84126/8914/1111/8900/5984/23514/7329/79728/8924/6233/2067/51426/672/146956/5932/7158/7311/6047/9025/79184/7156/5890/5983/6117/7334/5981/10714/5884/5810/5424/348654/83695/7314 92 Murine_minute_virus R-HSA-195258 RHO GTPase Effectors 167/2393 327/10654 1.3739023352918966e-30 5.113969803586504e-29 2.6915630545192127e-29 85415/3831/220134/5905/5170/55839/11130/84617/4928/25/79682/5903/10403/54908/6249/51517/55143/1495/1499/55055/25936/5525/9735/7531/5747/80776/4690/1783/1058/10093/991/1856/401541/79019/5526/4627/7532/10971/348235/80152/10458/10382/5578/9212/5594/1063/347688/8379/1027/3619/79172/1080/7533/2810/147841/147179/7277/348995/23421/55920/79023/10381/57122/79980/64105/6280/30851/6232/7534/332/1780/6242/23122/5528/5048/1781/5501/57405/8655/4085/5216/10552/100527963/81624/10094/10152/6279/6714/23279/55166/79902/3796/54821/5519/10092/8936/9183/1432/81565/4637/2491/10163/1062/699/999/347733/51466/22919/23081/1060/91687/995/3895/79003/11243/10376/391/5529/51143/998/4628/23028/83540/11004/1855/5527/2885/10096/701/10097/1857/9055/23191/7514/9184/8826/10499/5518/3799/10383/103910/54820/29984/5347/1729/57551/84643/5217/6396/10095/23332/25909/64946/9793/10726/30849/10109/81930/55746/140735/7280/5500/7529/5595/5515/1778/5516 167 Murine_minute_virus R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 111/2393 185/10654 1.5865527668958533e-28 5.7458938044336314e-27 3.024154633912437e-27 84946/6158/6138/6144/2091/6203/23246/55813/4736/6206/6194/22803/6191/6166/6128/6132/6147/25879/6129/6217/8780/6222/9277/1454/81887/6176/6152/6136/56902/10528/84135/27340/27043/6125/6224/6146/6154/6141/51602/6202/51096/6232/90459/6134/6169/6160/55781/6164/6155/6175/6218/6209/6193/6210/6229/6231/11224/6205/6165/6130/6142/6167/28987/6204/6228/23521/51077/6156/117246/10171/6235/5822/55720/6143/6181/6124/6207/6139/55759/705/6233/23160/7311/6223/25873/83732/26168/3921/6188/6189/51010/26354/6135/6201/6161/79707/56915/1453/51202/9045/6187/4691/6168/6208/6157/6137/10885/10813/6122/6133/6230 111 Murine_minute_virus R-HSA-162587 HIV Life Cycle 97/2393 152/10654 4.489059492692698e-28 1.5829841368968988e-26 8.331495457352099e-27 6884/23165/137492/5905/4928/2963/2237/6917/5434/5440/5903/902/9631/25978/51160/5430/27243/5436/7518/7520/404672/6749/348995/79023/57122/5441/23636/91782/5438/3981/3978/5431/7469/23511/79720/5435/4686/7316/5433/6872/4331/51271/23279/4927/8148/2966/79902/9150/2962/23327/9883/5437/8812/8732/23225/2965/27183/905/2068/5439/2071/5902/5901/8086/5478/6873/3836/6827/6233/2968/7514/1025/7311/9972/2967/93343/8021/7251/11198/6396/904/6883/7936/6829/1104/51497/2547/2961/1022/5432/55746/22916/8178/8480/92421/7314/25920 97 Murine_minute_virus R-HSA-8868773 rRNA processing in the nucleus and cytosol 114/2393 195/10654 7.42030830468754e-28 2.5495418277644368e-26 1.341864119876019e-26 84946/6158/6138/6144/2091/6203/55651/23246/55813/4736/6206/6194/22803/6191/6166/6128/6132/6147/25879/6129/6217/55226/8780/6222/9277/1454/81887/6176/6152/6136/56902/10528/84135/27340/27043/6125/6224/6146/6154/6141/51602/6202/51096/6232/90459/6134/6169/6160/55781/6164/6155/6175/6218/6209/6193/6210/6229/6231/11224/6205/6165/6130/6142/6167/28987/6204/1736/6228/23521/51077/6156/117246/10171/6235/5822/55720/6143/6181/6124/6207/6139/55759/705/6233/23160/7311/6223/25873/83732/26168/3921/6188/6189/51010/26354/6135/6201/6161/79707/56915/1453/51202/9045/6187/4691/6168/6208/6157/6137/10885/10813/6122/6133/6230 114 Murine_minute_virus R-HSA-5633007 Regulation of TP53 Activity 100/2393 160/10654 7.810308372187718e-28 2.6164533046828857e-26 1.3770806866752027e-26 23368/6884/1017/23774/6118/5170/80010/9891/83990/9156/5883/1763/1029/1459/7486/6446/10111/8445/207/9212/5982/1460/6749/11200/545/472/117584/54971/580/11073/7316/6872/28996/116028/890/80196/84289/1457/983/6790/641/1108/8148/64223/4194/5519/6119/5928/3364/1432/10524/10848/4683/144715/57459/1616/9099/6794/5985/54815/2033/84126/900/1111/3066/3065/7157/1107/8900/5984/91875/6873/5371/6233/5527/79109/2475/672/5932/7311/7161/5518/7156/5983/6117/11198/6883/7874/51230/1020/5884/5810/26155/83695/7314/253260/4193/5515/1263/5516 100 Murine_minute_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 64/2393 80/10654 8.695769881770276e-28 2.842032107700529e-26 1.4958063724739626e-26 3839/23165/4928/3837/3838/5903/5335/9631/4600/348995/9636/79023/317649/57122/23636/8638/25820/1982/7706/9470/23511/7316/2317/4734/3434/6772/23279/4927/79902/23586/8672/3840/9883/4939/6059/23225/1981/1973/3661/8086/7324/3836/9246/1977/51191/4599/6233/3716/7311/9972/7318/5610/8021/9775/4940/6396/7334/4938/55746/5495/1974/8480/7314/5595 64 Murine_minute_virus R-HSA-194315 Signaling by Rho GTPases 203/2393 455/10654 6.824390633942945e-27 2.1773055832103682e-25 1.145950306952825e-25 85415/3831/220134/5905/5170/55839/11130/84617/4928/25/79682/9743/5903/10403/54908/6249/51517/55143/57522/1495/1499/55055/25936/5525/392/9735/7531/5747/80776/4690/1783/1058/10093/991/1856/401541/79019/7204/5526/29/64411/4627/7532/10971/348235/80152/10458/10382/5578/9212/5594/1063/347688/613/8379/1027/3619/79172/11214/1080/7533/2810/147841/147179/7277/348995/23421/55920/79023/116985/54509/10381/57122/79980/64105/6280/30851/6232/7534/332/1780/6242/23122/5528/6453/5048/1781/5501/9824/57405/8655/50650/4085/5216/10552/100527963/81624/10094/10152/6279/23263/6714/23279/55166/393/79902/50649/3796/54821/5519/9826/10092/8936/9183/4650/1432/81565/4637/2491/10163/9138/1062/699/94134/999/23365/1123/347733/51466/22919/23081/85360/1060/91687/995/3895/79003/11243/10376/391/57584/5529/23221/51143/998/4628/23028/83540/51291/89941/11004/1855/5527/2885/7410/10096/701/10097/1857/9055/23191/7514/9184/8826/10499/5518/3799/10383/103910/54820/29984/5347/1729/57551/84643/5217/6396/10095/91614/23332/25909/64946/9793/10726/30849/10109/81930/55746/201176/9411/2665/140735/7280/5500/7529/80728/4952/5595/4983/5515/1778/5516/10672 203 Murine_minute_virus R-HSA-162599 Late Phase of HIV Life Cycle 90/2393 139/10654 8.080113491655532e-27 2.517988855539166e-25 1.3252572923890347e-25 6884/23165/137492/5905/4928/2963/6917/5434/5440/5903/902/9631/25978/51160/5430/27243/5436/404672/6749/348995/79023/57122/5441/23636/91782/5438/5431/7469/23511/79720/5435/4686/7316/5433/6872/4331/51271/23279/4927/8148/2966/79902/9150/2962/23327/9883/5437/8812/8732/23225/2965/27183/905/2068/5439/2071/5902/5901/8086/5478/6873/6827/6233/2968/7514/1025/7311/9972/2967/93343/8021/7251/11198/6396/904/6883/7936/6829/1104/51497/2961/1022/5432/55746/22916/8178/8480/92421/7314/25920 90 Murine_minute_virus R-HSA-1169408 ISG15 antiviral mechanism 59/2393 72/10654 9.191094657849956e-27 2.7991061003452136e-25 1.4732137370237969e-25 3839/23165/4928/3837/3838/5903/5335/9631/4600/348995/9636/79023/317649/57122/23636/25820/1982/7706/9470/23511/7316/2317/4734/3434/6772/23279/4927/79902/23586/8672/3840/9883/23225/1981/1973/3661/8086/7324/3836/9246/1977/51191/4599/6233/3716/7311/9972/7318/5610/8021/9775/6396/7334/55746/5495/1974/8480/7314/5595 59 Murine_minute_virus R-HSA-112382 Formation of RNA Pol II elongation complex 53/2393 61/10654 1.1242375074817264e-26 3.2749527391858986e-25 1.7236593364136307e-25 85403/2963/6917/5434/5440/902/6830/5430/5436/9646/404672/79577/6749/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/4298/54623/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/55677/2967/27125/11198/904/7936/6829/51497/4300/1022/5432/22916/8178/55840/80349/123169/25920 53 Murine_minute_virus R-HSA-75955 RNA Polymerase II Transcription Elongation 53/2393 61/10654 1.1242375074817264e-26 3.2749527391858986e-25 1.7236593364136307e-25 85403/2963/6917/5434/5440/902/6830/5430/5436/9646/404672/79577/6749/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/4298/54623/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/55677/2967/27125/11198/904/7936/6829/51497/4300/1022/5432/22916/8178/55840/80349/123169/25920 53 Murine_minute_virus R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 78/2393 112/10654 1.4321111927872842e-26 4.0830404219892784e-25 2.148968643152252e-25 6158/6138/6144/6203/4736/6206/6194/6191/6166/6128/6132/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/6154/6141/6202/6232/6134/6747/6169/6160/6731/6164/6155/6175/6218/6728/60559/6209/6193/6729/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/23521/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/6730/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133/6230 78 Murine_minute_virus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 55/2393 65/10654 2.0424926251109142e-26 5.701958578434636e-25 3.0010308307550713e-25 6118/6917/5434/5440/902/27339/5430/57804/5436/7515/5982/404672/54107/5441/5438/3978/5431/5435/7316/5433/4331/5425/5111/56655/5426/2966/6119/5437/5427/1161/1642/2965/5985/2033/2068/5439/2071/5984/6233/51426/2968/7311/2967/5983/6117/5981/3980/10714/7874/5424/1022/5432/91603/7314/8451 55 Murine_minute_virus R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 41/2393 42/10654 6.453746036241693e-26 1.7649019772579323e-24 9.288957775041749e-25 6118/80010/83990/7516/5888/5892/9156/5883/1763/7486/10111/675/5982/545/472/580/11073/116028/641/10635/7517/6119/3364/10524/4683/144715/5889/5985/84126/1111/5984/79728/672/5932/7156/5890/5983/6117/5884/5810/83695 41 Murine_minute_virus R-HSA-6782135 Dual incision in TC-NER 55/2393 66/10654 9.599946861297126e-26 2.57278575882763e-24 1.3540977678040155e-24 6118/6917/5434/5440/902/27339/5430/57804/5436/5982/404672/54107/5441/7507/5438/5431/2072/5435/7316/5433/4331/5425/5111/56655/5426/2966/6119/5437/5427/1161/1642/2965/5985/2033/2068/5439/2071/5984/6233/2067/51426/2968/7311/2967/5983/6117/5981/10714/7874/5424/1022/5432/91603/7314/8451 55 Murine_minute_virus R-HSA-376176 Signaling by ROBO receptors 119/2393 218/10654 2.3654373523887873e-25 6.215070690590147e-24 3.271089837152709e-24 10921/6158/6138/6144/25/55740/6203/5684/4736/6206/6194/2107/6191/6166/6128/6132/57522/2817/6147/10298/6129/4690/6217/5707/5567/6222/6176/6152/6136/5578/6125/27/6224/6146/6154/6141/26986/23053/6202/5705/10197/6232/26019/2935/6134/6169/6160/6091/22794/23122/6164/4686/7316/6155/6175/6218/5695/5216/65109/6209/5714/6193/6714/6210/6229/6231/11224/6205/6165/5566/6130/6142/6167/6204/4650/5701/6228/23521/5576/1605/5708/51466/5686/1981/7408/6156/6235/6143/6181/6124/998/6207/6139/6233/7311/6223/25873/3921/6188/6189/9775/5217/6135/6201/6161/23332/9045/6187/65110/6168/22916/6208/6157/6137/6122/80728/6133/7314/6230 119 Murine_minute_virus R-HSA-72312 rRNA processing 114/2393 205/10654 2.942829437292686e-25 7.583445088408076e-24 3.991286888635828e-24 84946/6158/6138/6144/2091/6203/55651/23246/55813/4736/6206/6194/22803/6191/6166/6128/6132/6147/25879/6129/6217/55226/8780/6222/9277/1454/81887/6176/6152/6136/56902/10528/84135/27340/27043/6125/6224/6146/6154/6141/51602/6202/51096/6232/90459/6134/6169/6160/55781/6164/6155/6175/6218/6209/6193/6210/6229/6231/11224/6205/6165/6130/6142/6167/28987/6204/1736/6228/23521/51077/6156/117246/10171/6235/5822/55720/6143/6181/6124/6207/6139/55759/705/6233/23160/7311/6223/25873/83732/26168/3921/6188/6189/51010/26354/6135/6201/6161/79707/56915/1453/51202/9045/6187/4691/6168/6208/6157/6137/10885/10813/6122/6133/6230 114 Murine_minute_virus R-HSA-5696398 Nucleotide Excision Repair 76/2393 111/10654 3.5744695338073594e-25 8.996911154697768e-24 4.735216397209351e-24 9318/6118/6917/5434/5440/902/27339/5430/57804/5436/10445/7515/5982/404672/54107/6613/5441/7507/7336/5438/3978/5431/2072/5435/7316/5433/4331/5425/5111/56655/5426/2966/6119/29844/7341/5437/5427/1161/1642/2965/5985/2033/142/2068/5439/10987/2071/5984/1069/7329/6233/2067/51426/2968/7311/2967/8607/5887/5983/6117/7334/5981/10038/3980/10714/7874/5424/1022/5432/91603/8178/5886/7508/7314/8451/7528 76 Murine_minute_virus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 54/2393 65/10654 3.6256209130871606e-25 8.996911154697768e-24 4.735216397209351e-24 2963/6917/5434/5440/4436/8621/902/5892/5430/5436/404672/6749/4292/545/472/5441/5438/5431/7469/5435/5433/4331/2966/5395/9150/2962/9656/5437/8812/2177/2965/51755/905/2068/5439/1111/2071/7157/55215/6827/2968/672/1025/2967/1386/11198/904/7936/6829/51497/1022/5432/8178/25920 54 Murine_minute_virus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 61/2393 79/10654 5.108037199977687e-25 1.2445036087218363e-23 6.550018993272823e-24 9318/6118/6917/5434/5440/902/27339/5430/57804/5436/7515/5982/404672/54107/5441/7507/5438/3978/5431/2072/5435/7316/5433/4331/5425/5111/56655/5426/2966/6119/5437/5427/1161/1642/2965/5985/2033/2068/5439/10987/2071/5984/6233/2067/51426/2968/7311/2967/5983/6117/5981/3980/10714/7874/5424/1022/5432/91603/8178/7314/8451 61 Murine_minute_virus R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 38/2393 39/10654 5.496345579988157e-24 1.3151969780685946e-22 6.92208935825576e-23 6118/80010/83990/7516/5888/5892/9156/5883/1763/7486/10111/675/5982/545/472/580/11073/116028/641/6119/3364/10524/4683/144715/5889/5985/84126/1111/5984/672/5932/7156/5890/5983/6117/5884/5810/83695 38 Murine_minute_virus R-HSA-162906 HIV Infection 122/2393 233/10654 8.05787684057314e-24 1.8943078888364926e-22 9.970041520192064e-23 6884/23165/137492/5905/8945/1173/4928/2963/3837/2237/6917/5434/5440/164/5684/5903/8065/902/162/9631/25978/51160/5707/5430/27243/5436/1174/7518/7520/4869/6500/404672/6749/348995/79023/57122/5705/5441/23636/10197/91782/160/5438/3981/3978/5431/7469/23511/79720/5435/4686/7316/293/5433/5695/6872/292/567/4331/51271/5714/23279/4927/8148/2966/79902/9150/2962/23327/9883/5701/5437/8812/8732/23225/5708/2965/5686/27183/905/2068/5439/2071/5902/5901/8086/5478/6873/3836/6827/6233/2968/7514/163/1025/7311/9972/2967/93343/8021/7251/8905/11198/6396/904/6883/7936/6829/1104/51497/2547/2961/1022/5432/55746/22916/8907/8178/8480/92421/7314/25920 122 Murine_minute_virus R-HSA-2408522 Selenoamino acid metabolism 77/2393 118/10654 1.933505117158025e-23 4.467063546537506e-22 2.351086077125003e-22 6158/6138/6144/6203/4736/6206/6194/6191/6166/6128/6132/6147/6129/6217/4143/6222/6176/6152/6136/6125/6224/6146/6154/6141/6202/6232/6134/6169/6160/6164/6155/6175/6218/79048/6209/6193/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/6228/51540/23521/6156/6235/6143/6181/6124/6207/6139/6233/51091/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133/7296/6230 77 Murine_minute_virus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 98/2393 171/10654 3.3619170935791755e-23 7.6355405176205e-22 4.0187055355897366e-22 10921/6158/6138/6144/6203/5684/4736/6206/6194/2107/6191/6166/6128/6132/6147/6129/6217/5707/6222/6176/6152/6136/6125/6224/6146/6154/6141/26986/23053/6202/5705/10197/6232/26019/2935/6134/6169/6160/6091/22794/6164/4686/7316/6155/6175/6218/5695/65109/6209/5714/6193/6210/6229/6231/11224/6205/6165/6130/6142/6167/6204/5701/6228/23521/1605/5708/5686/1981/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/9775/6135/6201/6161/9045/6187/65110/6168/22916/6208/6157/6137/6122/6133/7314/6230 98 Murine_minute_virus R-HSA-453274 Mitotic G2-G2/M phases 108/2393 198/10654 4.4811077451151275e-23 1.0007807297423784e-21 5.267266998644097e-22 10844/8454/115106/1017/8945/22995/84617/55559/5684/994/902/2305/22981/7531/51512/11190/5707/203068/54801/7532/84962/63943/1454/10382/3161/1063/347688/95681/6500/51400/121441/7277/79441/9133/10381/5705/10197/286826/5048/1781/23354/7316/1869/891/993/5695/890/8655/9738/4331/983/1639/6790/5714/55722/4957/1871/5566/5519/84131/9088/5928/5701/7840/7283/347733/5708/3320/22919/5686/80097/2033/995/10376/10426/5520/7157/8900/79866/1069/5577/6233/3326/80254/55957/7514/7311/54930/5518/10133/10383/54820/5347/9662/55142/23332/1453/7465/9793/1022/8481/93323/7280/5500/7314/5515/1778/5516 108 Murine_minute_virus R-HSA-166166 MyD88-independent TLR4 cascade 68/2393 99/10654 8.869832410585454e-23 1.9170282951910496e-21 1.0089622606268682e-21 8454/23643/1147/3665/8945/1326/5601/351/4790/6885/5606/5604/387522/7321/8737/1849/29110/5594/6500/23118/841/7099/8517/5528/7323/7316/79155/7335/5970/4792/4205/9261/4793/7322/5519/5598/1432/329/100302736/929/3656/10454/3661/3654/7189/5609/6233/10010/1385/6196/7311/5518/7187/1386/8772/9641/5599/353376/7334/3551/6416/5781/4791/7314/5595/5515/148022/5516 68 Murine_minute_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 68/2393 99/10654 8.869832410585454e-23 1.9170282951910496e-21 1.0089622606268682e-21 8454/23643/1147/3665/8945/1326/5601/351/4790/6885/5606/5604/387522/7321/8737/1849/29110/5594/6500/23118/841/7099/8517/5528/7323/7316/79155/7335/5970/4792/4205/9261/4793/7322/5519/5598/1432/329/100302736/929/3656/10454/3661/3654/7189/5609/6233/10010/1385/6196/7311/5518/7187/1386/8772/9641/5599/353376/7334/3551/6416/5781/4791/7314/5595/5515/148022/5516 68 Murine_minute_virus R-HSA-5685938 HDR through Single Strand Annealing (SSA) 36/2393 37/10654 1.0587956383972294e-22 2.252041516590932e-21 1.1852850087320697e-21 6118/80010/25/5893/83990/5888/9156/5883/1763/7486/10111/5982/545/472/580/11073/2072/116028/641/6119/3364/10524/4683/144715/5985/84126/5984/2067/672/5932/7156/5983/6117/5884/5810/83695 36 Murine_minute_virus R-HSA-168898 Toll-like Receptor Cascades 91/2393 155/10654 1.1991643350369386e-22 2.51075032648359e-21 1.3214475402545209e-21 54106/8454/23643/1147/3665/8945/1326/10695/5601/351/81793/4790/6885/5606/5604/387522/7321/8737/5336/1849/29110/5594/1785/4214/6500/23118/6280/841/10333/7099/8517/4615/7098/5528/7323/7316/79155/7335/5970/4792/7096/4205/9261/59307/4793/6279/5641/8651/7322/5519/5598/1432/329/100302736/929/3656/57162/10454/3661/3654/7189/5609/6233/51311/10010/1385/81622/6196/7311/5518/7187/1386/8772/9641/64145/5599/353376/7334/7097/3551/6416/5781/30849/4791/1508/51284/7314/5595/5515/148022/5516 91 Murine_minute_virus R-HSA-69275 G2/M Transition 106/2393 196/10654 2.7931122842959556e-22 5.758108401471663e-21 3.030583369195612e-21 10844/8454/115106/1017/8945/22995/84617/55559/5684/994/902/2305/22981/7531/51512/11190/5707/203068/54801/7532/84962/63943/1454/10382/3161/1063/347688/95681/6500/51400/121441/7277/79441/9133/10381/5705/10197/286826/5048/1781/23354/7316/891/993/5695/890/8655/9738/4331/983/1639/6790/5714/55722/4957/5566/5519/84131/9088/5928/5701/7840/7283/347733/5708/3320/22919/5686/80097/2033/995/10376/10426/5520/7157/8900/79866/1069/5577/6233/3326/80254/55957/7514/7311/54930/5518/10133/10383/54820/5347/9662/55142/23332/1453/7465/9793/1022/8481/93323/7280/5500/7314/5515/1778/5516 106 Murine_minute_virus R-HSA-113418 Formation of the Early Elongation Complex 33/2393 33/10654 3.3302298533871886e-22 6.660459706774377e-21 3.505505108828619e-21 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/2967/7936/6829/51497/1022/5432/22916/25920 33 Murine_minute_virus R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 33/2393 33/10654 3.3302298533871886e-22 6.660459706774377e-21 3.505505108828619e-21 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/2967/7936/6829/51497/1022/5432/22916/25920 33 Murine_minute_virus R-HSA-69242 S Phase 92/2393 161/10654 9.904200360080963e-22 1.951710070957131e-20 1.0272158268195424e-20 8454/1017/4172/6118/2237/1019/5684/994/902/8318/246184/1763/7027/7321/5707/57804/207/8697/1027/5982/6500/10274/54107/23244/4173/5705/10735/10197/4149/286826/23047/3978/91768/5885/7316/5422/1869/5753/993/5695/890/4331/5425/84515/5714/5111/56655/5426/4171/4609/51433/6119/5928/2932/5701/5427/6502/5708/5985/5686/990/1874/8243/9126/595/81620/8900/51529/5984/7324/64682/29945/10393/6233/51434/55957/51343/7311/114799/113130/23649/5983/6117/5001/5981/10714/7465/5424/1022/4176/7314/996 92 Murine_minute_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 99/2393 182/10654 3.922778849706231e-21 7.618150229864275e-20 4.0095527525601445e-20 23165/7150/5905/4928/5893/5903/1487/55143/83746/9631/5468/1029/8204/7486/1788/9112/6045/9212/51588/7518/3619/4869/3090/80012/10274/348995/51602/79023/6613/57122/23636/10735/8517/332/3183/5885/23511/28996/1655/5970/4792/3190/6996/9759/9612/6790/641/23137/6672/5111/2099/23279/4927/79902/9656/9883/7341/1387/10521/1616/23225/2033/23512/165918/8243/9126/142/7428/3066/3065/7157/1107/1069/6256/8086/7329/5987/5371/8924/672/7158/10155/9972/10499/5914/25942/8021/9641/6117/7690/6396/648/55746/4286/4791/8480/7508/6015/4193 99 Murine_minute_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 63/2393 92/10654 4.3500191501437855e-21 8.327179515989532e-20 4.3827260610471226e-20 6884/1017/6118/80010/9891/83990/9156/5883/1763/1459/7486/10111/8445/9212/5982/1460/6749/11200/545/472/580/11073/7316/6872/28996/116028/890/1457/6790/641/8148/4194/6119/3364/1432/10524/4683/144715/6794/5985/84126/1111/7157/8900/5984/6873/6233/672/5932/7311/7156/5983/6117/11198/6883/1020/5884/5810/26155/83695/7314/4193/1263 63 Murine_minute_virus R-HSA-674695 RNA Polymerase II Pre-transcription Events 59/2393 84/10654 1.0661589257487999e-20 2.0121872683146366e-19 1.0590459306919139e-19 6884/85403/2963/6917/5434/5440/902/6830/5430/5436/9646/404672/79577/6749/5441/5438/5431/7469/5435/4686/5433/6872/4331/8148/2966/9150/2962/4298/54623/5437/8812/2965/905/2068/5439/2071/6873/6827/2968/1025/55677/2967/27125/11198/904/6883/7936/6829/51497/4300/2961/1022/5432/22916/8178/55840/80349/123169/25920 59 Murine_minute_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 78/2393 129/10654 1.0851273583910031e-20 2.0195425836721447e-19 1.0629171493011287e-19 8454/23643/1147/3665/8945/1326/5601/351/4790/6885/5606/5604/387522/7321/8737/5336/1849/29110/5594/1785/4214/6500/23118/841/10333/7099/8517/4615/5528/7323/7316/79155/7335/5970/4792/7096/4205/9261/59307/4793/8651/7322/5519/5598/1432/329/100302736/929/3656/57162/10454/3661/3654/7189/5609/6233/10010/1385/6196/7311/5518/7187/1386/8772/9641/5599/353376/7334/7097/3551/6416/5781/4791/7314/5595/5515/148022/5516 78 Murine_minute_virus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 120/2393 244/10654 1.8165453677600763e-20 3.33448053808014e-19 1.754989756884284e-19 10921/8449/23165/7919/4928/2963/5434/5440/5903/220988/6432/6431/6430/6627/24148/9631/27339/5430/4904/5436/9879/10523/6428/11325/9128/3184/8106/25804/27238/9589/3178/23450/348995/79023/57122/5441/23636/3183/5438/85313/5431/9092/5093/22794/23511/81608/5435/10594/4686/6625/5433/10713/1655/9343/29107/3185/3190/9416/65109/6626/84321/5546/1478/23279/4927/79902/2962/10898/22938/9883/10236/5437/6629/4670/10569/23225/10189/9295/10482/10949/3181/5439/1660/23283/8086/2521/1977/3191/9410/57794/27316/3187/9972/6634/5094/51593/8021/9775/3192/6396/6427/3312/5356/2733/6426/84950/84991/5432/55746/22916/56259/5725/1479/26121/11100/8480/10992/10262/6628/1994 120 Murine_minute_virus R-HSA-2990846 SUMOylation 100/2393 188/10654 2.196020298417379e-20 3.976577297134173e-19 2.0929354195443011e-19 10054/23165/7150/5905/4928/5893/5903/1487/55143/83746/9631/5468/1029/8204/7486/1788/9112/6045/9212/51588/7518/3619/4869/3090/80012/10274/348995/51602/79023/6613/57122/23636/10735/8517/332/3183/5885/23511/28996/1655/5970/4792/3190/6996/9759/9612/6790/641/23137/6672/5111/2099/23279/4927/79902/9656/9883/7341/1387/10521/1616/23225/2033/23512/165918/8243/9126/142/7428/3066/3065/7157/1107/1069/6256/8086/7329/5987/5371/8924/672/7158/10155/9972/10499/5914/25942/8021/9641/6117/7690/6396/648/55746/4286/4791/8480/7508/6015/4193 100 Murine_minute_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 63/2393 94/10654 2.5091027018195947e-20 4.482930160584342e-19 2.359436926623338e-19 8454/1147/3665/8945/1326/5601/351/4790/6885/5606/5604/387522/7321/8737/1849/29110/5594/6500/23118/841/8517/7098/5528/7323/7316/79155/7335/5970/4792/4205/9261/4793/7322/5519/5598/1432/329/3656/10454/3661/3654/7189/5609/6233/10010/1385/6196/7311/5518/7187/1386/8772/9641/5599/7334/3551/6416/4791/7314/5595/5515/148022/5516 63 Murine_minute_virus R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 41/2393 48/10654 2.6215350924560766e-20 4.622180294593609e-19 2.4327264708387414e-19 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/22916/8178/25920 41 Murine_minute_virus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 60/2393 88/10654 5.358161719503613e-20 9.32459312225304e-19 4.907680590659494e-19 8454/115106/8945/22995/55559/22981/7531/11190/203068/54801/7532/84962/1454/10382/95681/6500/121441/7277/79441/9133/5048/1781/23354/7316/891/8655/9738/983/1639/6790/55722/4957/5566/84131/7840/7283/3320/22919/79866/1069/5577/6233/80254/7311/54930/5518/10133/10383/54820/5347/9662/55142/23332/1453/9793/8481/93323/5500/7314/1778 60 Murine_minute_virus R-HSA-877300 Interferon gamma signaling 61/2393 92/10654 2.312430020764086e-19 3.972636189517789e-18 2.0908611523777837e-18 3135/3665/3120/3460/6737/10379/115362/960/7412/3117/3107/3119/4502/2633/9021/85363/9830/3123/163351/23650/2209/3383/8638/7706/2634/3113/3662/3115/4684/3122/3394/3663/115361/3664/567/6672/6772/8651/3659/3106/4939/388646/7341/10437/2635/3661/5371/3716/81603/10107/3133/3134/3127/4940/7726/4938/4261/5781/3105/3660/5724 61 Murine_minute_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 63/2393 97/10654 2.971584085356913e-19 5.0404084485800805e-18 2.652846551884253e-18 54106/8454/23643/1147/3665/8945/1326/5601/351/4790/6885/5606/5604/387522/1849/5594/4214/6500/23118/7099/8517/4615/5528/7316/79155/7335/5970/4792/4205/9261/4793/5519/5598/1432/100302736/929/3656/57162/10454/3654/7189/5609/6233/51311/1385/6196/7311/5518/1386/64145/5599/353376/7334/3551/6416/30849/4791/51284/7314/5595/5515/148022/5516 63 Murine_minute_virus R-HSA-167169 HIV Transcription Elongation 39/2393 46/10654 3.8809807448408407e-19 6.342090485471617e-18 3.3379423607745353e-18 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/22916/8178/25920 39 Murine_minute_virus R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 39/2393 46/10654 3.8809807448408407e-19 6.342090485471617e-18 3.3379423607745353e-18 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/22916/8178/25920 39 Murine_minute_virus R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 39/2393 46/10654 3.8809807448408407e-19 6.342090485471617e-18 3.3379423607745353e-18 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/22916/8178/25920 39 Murine_minute_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 61/2393 93/10654 5.264440999585154e-19 8.398036832671556e-18 4.420019385616609e-18 54106/8454/23643/1147/3665/8945/1326/5601/351/4790/6885/5606/5604/387522/1849/5594/4214/6500/23118/7099/8517/4615/5528/7316/79155/7335/5970/4792/4205/9261/4793/5519/5598/1432/100302736/929/3656/57162/10454/3654/7189/5609/6233/51311/1385/6196/7311/5518/1386/5599/353376/7334/3551/6416/4791/51284/7314/5595/5515/148022/5516 61 Murine_minute_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 61/2393 93/10654 5.264440999585154e-19 8.398036832671556e-18 4.420019385616609e-18 54106/8454/23643/1147/3665/8945/1326/5601/351/4790/6885/5606/5604/387522/1849/5594/4214/6500/23118/7099/8517/4615/5528/7316/79155/7335/5970/4792/4205/9261/4793/5519/5598/1432/100302736/929/3656/57162/10454/3654/7189/5609/6233/51311/1385/6196/7311/5518/1386/5599/353376/7334/3551/6416/4791/51284/7314/5595/5515/148022/5516 61 Murine_minute_virus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 57/2393 84/10654 6.56489442561992e-19 1.0349362976859638e-17 5.447033145715599e-18 9318/6118/902/57804/10445/7515/5982/404672/54107/6613/7507/7336/3978/2072/7316/4331/5425/5111/56655/5426/2966/6119/29844/7341/5427/1642/2965/5985/142/2068/10987/2071/5984/1069/7329/6233/2067/51426/2968/7311/2967/8607/5887/5983/6117/7334/5981/10038/3980/10714/5424/1022/5886/7508/7314/8451/7528 57 Murine_minute_virus R-HSA-5696400 Dual Incision in GG-NER 36/2393 41/10654 8.105176578103572e-19 1.2628996063556728e-17 6.646840033450909e-18 6118/57804/5982/404672/54107/7507/2072/7316/5425/5111/56655/5426/2966/6119/5427/1642/2965/5985/142/2068/2071/5984/6233/2067/51426/2968/7311/2967/5983/6117/5981/10038/10714/5424/7314/8451 36 Murine_minute_virus R-HSA-6804757 Regulation of TP53 Degradation 33/2393 36/10654 1.1474369296124939e-18 1.767316650207749e-17 9.301666580040785e-18 1017/5170/1029/6446/207/11200/472/117584/7316/890/80196/983/64223/4194/5519/1616/9099/900/7157/8900/6233/5527/79109/2475/7311/5518/7874/51230/7314/253260/4193/5515/5516 33 Murine_minute_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 54/2393 78/10654 1.3401434408888295e-18 2.0406729668079904e-17 1.0740384035831526e-17 1147/3665/351/7186/4790/80143/7321/8737/9140/29110/57506/79132/4214/9636/54476/841/7706/8517/84166/8887/7323/9474/7316/5970/4792/4793/23586/7322/7128/1387/843/2033/64135/83737/3661/9246/7189/51191/6233/10010/7311/55593/84282/7318/79671/7187/5094/8772/9641/1540/3551/3456/4791/7314 54 Murine_minute_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 60/2393 92/10654 1.567682777400319e-18 2.360331372715087e-17 1.2422796698500456e-17 54106/8454/23643/1147/8945/1326/5601/351/4790/6885/5606/5604/387522/1849/5594/4214/6500/23118/7099/8517/4615/5528/7316/79155/7335/5970/4792/4205/9261/4793/5519/5598/1432/100302736/929/3656/57162/10454/3654/7189/5609/6233/51311/1385/6196/7311/5518/1386/5599/353376/7334/3551/6416/4791/51284/7314/5595/5515/148022/5516 60 Murine_minute_virus R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 45/2393 59/10654 2.064113380005402e-18 3.073235476896932e-17 1.617492356261543e-17 6203/6206/6194/1965/6191/6217/6222/8667/6224/10480/26986/6202/6232/6218/6209/6193/6210/6229/6231/6205/6204/8663/6228/8894/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/6201/1978/6187/6208/1974/1968/6230 45 Murine_minute_virus R-HSA-72649 Translation initiation complex formation 44/2393 58/10654 7.116530705598609e-18 1.0365381679893625e-16 5.455464042049277e-17 6203/6206/6194/1965/6191/6217/6222/8667/6224/10480/26986/6202/6232/6218/6209/6193/6210/6229/6231/6205/6204/8663/6228/8894/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/6201/6187/6208/1974/1968/6230 44 Murine_minute_virus R-HSA-72702 Ribosomal scanning and start codon recognition 44/2393 58/10654 7.116530705598609e-18 1.0365381679893625e-16 5.455464042049277e-17 6203/6206/6194/1965/6191/6217/6222/1983/8667/6224/10480/6202/6232/6218/6209/6193/6210/6229/6231/6205/6204/8663/6228/8894/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/6201/6187/6208/1974/1968/6230 44 Murine_minute_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 33/2393 37/10654 8.325794979331348e-18 1.199630674441291e-16 6.313845654954162e-17 1017/5170/1029/6446/207/11200/472/117584/7316/890/80196/983/64223/4194/5519/1616/9099/900/7157/8900/6233/5527/79109/2475/7311/5518/7874/51230/7314/253260/4193/5515/5516 33 Murine_minute_virus R-HSA-5656169 Termination of translesion DNA synthesis 30/2393 32/10654 9.254396420022155e-18 1.3192437449818818e-16 6.943388131483588e-17 6118/57804/5982/54107/9636/7706/7316/11201/5425/5111/56655/5426/9100/6119/51455/5427/5429/5985/5984/9246/6233/51426/7311/7318/5983/6117/5981/10714/5424/7314 30 Murine_minute_virus R-HSA-72086 mRNA Capping 28/2393 29/10654 1.392911024050455e-17 1.9647376549764312e-16 1.0340724499875954e-16 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/4686/5433/4331/2966/2962/5437/8732/2965/2068/5439/2071/2968/2967/6829/1022/5432/22916 28 Murine_minute_virus R-HSA-5693537 Resolution of D-Loop Structures 31/2393 34/10654 1.9478409271462278e-17 2.690831796263861e-16 1.4162272611915058e-16 51750/80010/83990/7516/5888/5892/9156/1763/7486/10111/675/472/80198/580/116028/197342/641/10635/7517/84464/10524/4683/5889/23514/79728/672/146956/5932/7156/5890/348654 31 Murine_minute_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 31/2393 34/10654 1.9478409271462278e-17 2.690831796263861e-16 1.4162272611915058e-16 7321/9140/29110/57506/9636/54476/7706/84166/8887/7323/9474/7316/23586/7322/7128/64135/83737/3661/9246/51191/6233/7311/55593/84282/7318/79671/7187/5094/9641/1540/7314 31 Murine_minute_virus R-HSA-72163 mRNA Splicing - Major Pathway 93/2393 183/10654 2.5568523740439905e-17 3.4961042665499463e-16 1.8400548771315503e-16 10921/8449/2963/5434/5440/220988/6432/6431/6430/6627/24148/27339/5430/4904/5436/9879/10523/6428/11325/9128/3184/8106/25804/27238/3178/23450/5441/3183/5438/85313/5431/9092/5093/22794/81608/5435/10594/4686/6625/5433/10713/1655/9343/3185/3190/9416/65109/6626/5546/1478/2962/10898/22938/10236/5437/6629/4670/10569/10189/9295/10949/3181/5439/1660/23283/2521/3191/9410/57794/27316/3187/6634/5094/51593/9775/3192/6427/3312/5356/6426/84950/84991/5432/22916/56259/5725/1479/26121/11100/10992/10262/6628/1994 93 Murine_minute_virus R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 25/2393 25/10654 5.538041659554184e-17 7.495935175558188e-16 3.9452290397674675e-16 6118/57804/7515/5982/54107/3978/7316/5425/5111/56655/5426/6119/5427/5985/5984/6233/51426/7311/5983/6117/5981/3980/10714/5424/7314 25 Murine_minute_virus R-HSA-5693568 Resolution of D-loop Structures through Holliday Junction Intermediates 30/2393 33/10654 7.989532830601332e-17 1.0705973993005785e-15 5.634723154213571e-16 80010/83990/7516/5888/5892/9156/1763/7486/10111/675/472/80198/580/116028/197342/641/10635/7517/84464/10524/4683/5889/23514/79728/672/146956/5932/7156/5890/348654 30 Murine_minute_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 59/2393 95/10654 9.444714089078258e-17 1.2407761646436143e-15 6.530400866545338e-16 8454/23643/1147/8945/1326/5601/351/4790/6885/5606/5604/387522/1849/5594/4214/6500/23118/10333/7099/8517/4615/5528/7316/79155/7335/5970/4792/7096/4205/9261/59307/4793/8651/5519/5598/1432/929/3656/57162/10454/3654/7189/5609/6233/1385/6196/7311/5518/1386/5599/7334/7097/3551/6416/4791/7314/5595/5515/5516 59 Murine_minute_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 59/2393 95/10654 9.444714089078258e-17 1.2407761646436143e-15 6.530400866545338e-16 8454/23643/1147/8945/1326/5601/351/4790/6885/5606/5604/387522/1849/5594/4214/6500/23118/10333/7099/8517/4615/5528/7316/79155/7335/5970/4792/7096/4205/9261/59307/4793/8651/5519/5598/1432/929/3656/57162/10454/3654/7189/5609/6233/1385/6196/7311/5518/1386/5599/7334/7097/3551/6416/4791/7314/5595/5515/5516 59 Murine_minute_virus R-HSA-73893 DNA Damage Bypass 38/2393 48/10654 1.0310259146020448e-16 1.3413346850162523e-15 7.059656236927643e-16 6118/57804/56852/5982/54107/9636/7706/7316/11201/5425/5111/56655/5426/9100/10459/7415/6119/51455/5427/1642/5429/5985/7398/5984/9246/57599/6233/51426/7311/7318/5983/6117/5981/10714/55666/5424/7314/8451 38 Murine_minute_virus R-HSA-5693607 Processing of DNA double-strand break ends 60/2393 98/10654 1.3812099242832137e-16 1.7796358639802945e-15 9.366504547264708e-16 1017/6118/80010/54962/83990/151987/9156/5883/1763/7486/10111/51588/51720/5982/63967/5531/51548/545/472/6613/7336/580/11073/29086/7316/116028/890/641/9656/6119/3364/7341/10524/4683/144715/5985/165918/84126/8914/1111/8900/5984/7329/8924/6233/672/5932/7158/7311/6047/9025/79184/7156/5983/6117/7334/5884/5810/83695/7314 60 Murine_minute_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 45/2393 63/10654 1.5153992417524904e-16 1.9339380799507975e-15 1.0178621473425248e-15 1147/3665/170506/55718/5434/5440/6737/4790/1499/8737/29110/81844/7520/23220/147945/5441/51082/8517/6778/4615/7098/5591/5435/7316/51428/5970/4792/4793/3428/1387/5437/2033/22954/1660/3661/6233/7311/197358/81030/661/3551/2547/4791/7314/148022 45 Murine_minute_virus R-HSA-69481 G2/M Checkpoints 86/2393 168/10654 2.322309454673395e-16 2.9357496879833486e-15 1.5451314147280781e-15 1017/4172/6118/80010/5684/83990/8318/9156/5883/1763/7531/51512/7486/5707/10111/7532/8317/10971/51588/51720/5982/63967/7533/2810/4173/11200/545/9133/472/5705/10197/7336/7534/580/11073/29086/7316/891/993/5695/116028/983/84515/641/5714/4171/9656/9088/6119/3364/7341/5701/10524/4683/10926/144715/5708/5985/5686/990/995/165918/84126/1111/7157/5984/8924/6233/672/5932/7158/7311/9025/79184/7156/5983/6117/7334/5001/7465/5884/5810/83695/4176/7529/7314 86 Murine_minute_virus R-HSA-3371556 Cellular response to heat stress 56/2393 89/10654 2.450287950040359e-16 3.068584909396337e-15 1.615044689155967e-15 23165/3303/6118/4928/5903/9631/7531/1915/5594/3308/84335/10049/348995/10013/545/79023/472/57122/23636/3313/23511/3305/9261/9532/23279/4927/7415/79902/64223/6119/26353/9883/2932/1387/57805/23225/3309/3320/2033/8086/22824/3326/2475/3306/9972/23411/8021/6117/6396/3304/3312/57521/55746/8480/10728/5595 56 Murine_minute_virus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 33/2393 39/10654 2.531163497151028e-16 3.1405176723910903e-15 1.6529040381005738e-15 6118/57804/5982/54107/9636/7706/7316/11201/5425/5111/56655/5426/9100/10459/7415/6119/51455/5427/5429/5985/5984/9246/6233/51426/7311/7318/5983/6117/5981/10714/55666/5424/7314 33 Murine_minute_virus R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 26/2393 27/10654 2.6168260190398395e-16 3.1877698777394407e-15 1.6777736198628634e-15 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/5433/4331/2966/2962/5437/8732/2965/2068/5439/2071/2968/2967/6829/1022/5432 26 Murine_minute_virus R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 26/2393 27/10654 2.6168260190398395e-16 3.1877698777394407e-15 1.6777736198628634e-15 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/5433/4331/2966/2962/5437/8732/2965/2068/5439/2071/2968/2967/6829/1022/5432 26 Murine_minute_virus R-HSA-453279 Mitotic G1-G1/S phases 79/2393 149/10654 2.89114256063662e-16 3.4902081362640272e-15 1.8369516506652777e-15 8454/1017/4172/6118/25/1019/5684/902/8318/7027/1029/5707/8317/207/1027/6500/54107/4173/5705/10197/4149/286826/91768/7316/5422/1869/891/5753/993/5695/890/4331/983/84515/5714/5111/56655/5426/6714/4171/4609/1871/51053/1031/5519/6119/5928/5701/10926/5427/4067/6502/5708/5686/990/1021/1874/595/81620/3065/5520/8900/6233/1032/55957/7311/5518/23649/6117/1719/5001/7465/1022/1859/4176/7314/5515/6241/5516 79 Murine_minute_virus R-HSA-5663202 Diseases of signal transduction 153/2393 377/10654 7.50859514576165e-16 8.88208981610267e-15 4.6747841137382476e-015 8454/4000/1147/2308/27044/5170/2963/5434/5440/5684/22906/11052/6464/8841/5335/79718/1487/142678/2309/1499/5604/5525/892/55750/139285/5707/5430/5526/8844/207/5436/1452/5594/4303/84335/613/4041/1027/7249/6500/409/5908/7414/10533/10013/2064/5705/5441/23164/10197/5438/5431/5528/2100/5435/4686/7316/5433/9611/5695/3714/8546/6774/9759/8658/9612/102/50852/57085/5714/6772/6714/2099/5605/4609/10818/7415/64223/4089/10014/2962/22938/5519/2932/5701/867/1387/5437/7046/4088/6907/29851/3164/5708/3320/5686/324/2335/2033/391/55294/5728/6400/8312/5529/5439/3066/3065/2066/5894/9794/6233/5527/2885/1488/79109/2475/56829/8660/1385/7048/7311/8826/5906/9846/2931/5518/57534/1956/4140/7040/3845/6777/3265/3516/369/80351/5781/4851/5432/22916/7750/11140/5245/7529/7314/1523/57670/253260/5595/4193/5515/5516 153 Murine_minute_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 59/2393 98/10654 7.556404768923168e-16 8.88208981610267e-15 4.6747841137382476e-015 8454/23643/1147/8945/1326/5601/351/4790/6885/5606/5604/387522/1849/5594/4214/6500/23118/10333/7099/8517/4615/5528/7316/79155/7335/5970/4792/7096/4205/9261/59307/4793/8651/5519/5598/1432/929/3656/57162/10454/3654/7189/5609/6233/1385/6196/7311/5518/1386/5599/7334/7097/3551/6416/4791/7314/5595/5515/5516 59 Murine_minute_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 59/2393 98/10654 7.556404768923168e-16 8.88208981610267e-15 4.6747841137382476e-015 8454/23643/1147/8945/1326/5601/351/4790/6885/5606/5604/387522/1849/5594/4214/6500/23118/10333/7099/8517/4615/5528/7316/79155/7335/5970/4792/7096/4205/9261/59307/4793/8651/5519/5598/1432/929/3656/57162/10454/3654/7189/5609/6233/1385/6196/7311/5518/1386/5599/7334/7097/3551/6416/4791/7314/5595/5515/5516 59 Murine_minute_virus R-HSA-72172 mRNA Splicing 93/2393 191/10654 8.737288270565202e-16 1.0180840245702061e-14 5.358336971422137e-15 10921/8449/2963/5434/5440/220988/6432/6431/6430/6627/24148/27339/5430/4904/5436/9879/10523/6428/11325/9128/3184/8106/25804/27238/3178/23450/5441/3183/5438/85313/5431/9092/5093/22794/81608/5435/10594/4686/6625/5433/10713/1655/9343/3185/3190/9416/65109/6626/5546/1478/2962/10898/22938/10236/5437/6629/4670/10569/10189/9295/10949/3181/5439/1660/23283/2521/3191/9410/57794/27316/3187/6634/5094/51593/9775/3192/6427/3312/5356/6426/84950/84991/5432/22916/56259/5725/1479/26121/11100/10992/10262/6628/1994 93 Murine_minute_virus R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 23/2393 23/10654 1.114679962496091e-15 1.2876475428834153e-14 6.777092330965344e-15 2963/5434/5440/5430/5436/5441/5438/5431/7469/5435/4686/5433/9150/2962/5437/5439/6827/7936/6829/51497/5432/22916/25920 23 Murine_minute_virus R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 25/2393 26/10654 1.1314403034517171e-15 1.2958376125002572e-14 6.820197960527669e-15 51750/80010/83990/7516/5888/5892/9156/1763/7486/10111/675/472/580/116028/641/10635/7517/10524/4683/5889/79728/672/5932/7156/5890 25 Murine_minute_virus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 50/2393 77/10654 1.5058243577561797e-15 1.710003931689221e-14 9.000020693101163e-15 23165/4928/5893/5903/9631/1029/7486/6045/51588/7518/80012/10274/348995/79023/6613/57122/23636/10735/5885/23511/6996/641/23137/6672/23279/4927/79902/9656/9883/7341/23225/165918/8243/9126/142/1069/8086/7329/5371/8924/672/9972/8021/6117/6396/648/55746/8480/7508/6015 50 Murine_minute_virus R-HSA-167172 Transcription of the HIV genome 48/2393 73/10654 2.662788767595373e-15 2.973447457148167e-14 1.564972345867456e-14 6884/2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/4686/5433/6872/4331/8148/2966/9150/2962/5437/8812/8732/2965/905/2068/5439/2071/6873/6827/2968/1025/2967/11198/904/6883/7936/6829/51497/2961/1022/5432/22916/8178/25920 48 Murine_minute_virus R-HSA-8854518 AURKA Activation by TPX2 48/2393 73/10654 2.662788767595373e-15 2.973447457148167e-14 1.564972345867456e-14 115106/22995/55559/22981/7531/11190/203068/54801/7532/1454/10382/3161/95681/121441/7277/79441/5048/1781/23354/8655/9738/983/1639/6790/55722/4957/5566/84131/7840/7283/3320/22919/1069/5577/80254/54930/5518/10383/54820/5347/9662/55142/23332/1453/9793/8481/93323/1778 48 Murine_minute_virus R-HSA-69473 G2/M DNA damage checkpoint 57/2393 95/10654 2.9050684452444455e-15 3.2171832368822786e-14 1.693254335201199e-14 6118/80010/83990/9156/5883/1763/7531/7486/10111/7532/10971/51588/51720/5982/7533/2810/11200/545/472/7336/7534/580/11073/29086/891/116028/983/641/9656/6119/3364/7341/10524/4683/144715/5985/995/165918/84126/1111/7157/5984/8924/672/5932/7158/9025/79184/7156/5983/6117/7334/7465/5884/5810/83695/7529 57 Murine_minute_virus R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 38/2393 51/10654 3.6191026432166335e-15 3.9750799523854825e-14 2.0921473433607804e-14 6203/6206/6194/1965/6191/6217/6222/8667/6224/10480/6202/6232/6218/6209/6193/6210/6229/6231/6205/6204/8663/6228/8894/6235/6207/6233/6223/8664/3646/51386/3921/6188/6189/6201/6187/6208/1968/6230 38 Murine_minute_virus R-HSA-168325 Viral Messenger RNA Synthesis 34/2393 43/10654 4.687964404920233e-15 5.107213254140742e-14 2.688006975863548e-14 23165/4928/2963/5434/5440/5903/9631/5430/5436/348995/79023/57122/5441/23636/5438/5431/23511/5435/5433/23279/4927/79902/2962/9883/5437/23225/5439/8086/9972/8021/6396/5432/55746/8480 34 Murine_minute_virus R-HSA-180786 Extension of Telomeres 27/2393 30/10654 5.404261544958495e-15 5.840089088906761e-14 3.073731099424611e-14 6118/2237/55651/7015/1763/57804/5982/54107/3978/5422/10856/5425/5111/56655/5426/6119/1736/5427/5985/5984/23649/8607/5983/6117/5981/10714/5424 27 Murine_minute_virus R-HSA-2262752 Cellular responses to stress 181/2393 479/10654 6.242565910886368e-15 6.692030656470187e-14 3.522121398142203e-14 1017/23165/3303/7014/6118/84617/4928/55846/1019/5684/5903/5601/2077/4790/5606/9631/9448/246184/112399/7531/7290/7027/1029/1915/1783/7321/5707/2146/10111/475/84962/6045/8697/10382/57690/5594/3308/347688/84335/23677/1027/80012/10049/58528/10294/3091/830/7013/7277/348995/1051/10013/50488/545/79023/472/10381/57122/5705/23636/10197/3313/1780/7001/23511/7323/1781/7316/2114/1869/5695/890/3305/8655/6774/5970/1639/9261/9532/832/5714/2289/23279/4927/7415/1871/8994/51433/79902/64223/4194/1031/7322/6119/26353/5598/9883/5928/1432/2932/5701/10524/1387/4683/57805/23225/112398/3309/347733/5708/3320/65057/5686/2033/23512/1021/10376/6009/51143/3301/7428/192669/7157/8900/51529/6648/8086/7324/10963/64682/29945/10393/22824/5609/8131/6233/51434/3326/2475/1032/3306/51343/6196/7311/9972/2034/57634/10383/23411/8021/55662/6117/5599/6396/648/3304/3312/26523/3456/5052/6416/54386/96459/3569/57521/55746/55466/140735/7280/8480/768/10728/7296/7314/51164/996/6015/5595/4193/1778/23043 181 Murine_minute_virus R-HSA-380259 Loss of Nlp from mitotic centrosomes 46/2393 70/10654 1.0519708799948643e-14 1.1099535269237151e-13 5.841860668019553e-14 115106/22995/55559/22981/7531/11190/203068/54801/7532/1454/10382/95681/121441/7277/79441/5048/1781/23354/8655/9738/983/1639/55722/4957/5566/84131/7840/7283/3320/22919/1069/5577/80254/54930/5518/10383/54820/5347/9662/55142/23332/1453/9793/8481/93323/1778 46 Murine_minute_virus R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 46/2393 70/10654 1.0519708799948643e-14 1.1099535269237151e-13 5.841860668019553e-14 115106/22995/55559/22981/7531/11190/203068/54801/7532/1454/10382/95681/121441/7277/79441/5048/1781/23354/8655/9738/983/1639/55722/4957/5566/84131/7840/7283/3320/22919/1069/5577/80254/54930/5518/10383/54820/5347/9662/55142/23332/1453/9793/8481/93323/1778 46 Murine_minute_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 52/2393 85/10654 1.5575020656616316e-14 1.605425206143528e-13 8.449606348123831e-14 8454/1147/8945/1326/5601/351/81793/4790/6885/5606/5604/387522/1849/5594/4214/6500/23118/8517/4615/5528/7316/79155/7335/5970/4792/4205/9261/4793/5519/5598/1432/3656/57162/10454/3654/7189/5609/6233/1385/6196/7311/5518/1386/5599/7334/3551/6416/4791/7314/5595/5515/5516 52 Murine_minute_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 52/2393 85/10654 1.5575020656616316e-14 1.605425206143528e-13 8.449606348123831e-14 8454/1147/8945/1326/5601/351/81793/4790/6885/5606/5604/387522/1849/5594/4214/6500/23118/8517/4615/5528/7316/79155/7335/5970/4792/4205/9261/4793/5519/5598/1432/3656/57162/10454/3654/7189/5609/6233/1385/6196/7311/5518/1386/5599/7334/3551/6416/4791/7314/5595/5515/5516 52 Murine_minute_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 52/2393 85/10654 1.5575020656616316e-14 1.605425206143528e-13 8.449606348123831e-14 8454/1147/8945/1326/5601/351/81793/4790/6885/5606/5604/387522/1849/5594/4214/6500/23118/8517/4615/5528/7316/79155/7335/5970/4792/4205/9261/4793/5519/5598/1432/3656/57162/10454/3654/7189/5609/6233/1385/6196/7311/5518/1386/5599/7334/3551/6416/4791/7314/5595/5515/5516 52 Murine_minute_virus R-HSA-450294 MAP kinase activation 43/2393 64/10654 2.3690863256530682e-14 2.423340210973367e-13 1.275442216301772e-13 8454/1147/8945/1326/5601/4790/6885/5606/5604/387522/1849/5594/6500/23118/8517/5528/7316/79155/7335/4205/9261/5519/5598/1432/3656/10454/3654/7189/5609/6233/1385/6196/7311/5518/1386/5599/7334/3551/6416/7314/5595/5515/5516 43 Murine_minute_virus R-HSA-69206 G1/S Transition 69/2393 131/10654 3.457356139366052e-14 3.5097403232958407e-13 1.8472317491030738e-13 8454/1017/4172/6118/1019/5684/902/8318/7027/5707/8317/207/1027/6500/54107/4173/5705/10197/4149/286826/91768/7316/5422/1869/891/5753/993/5695/890/4331/983/84515/5714/5111/56655/5426/4171/4609/51053/5519/6119/5928/5701/10926/5427/6502/5708/5686/990/1874/595/81620/3065/8900/6233/55957/7311/5518/23649/6117/1719/5001/7465/1022/4176/7314/5515/6241/5516 69 Murine_minute_virus R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 55/2393 94/10654 4.03526939680074e-14 4.0656097682052567e-13 2.1397946148448717e-13 10844/115106/22995/84617/55559/22981/7531/11190/203068/54801/7532/1454/10382/347688/95681/121441/7277/79441/10381/5048/1781/23354/8655/9738/983/1639/55722/4957/5566/84131/7840/7283/347733/3320/22919/80097/10376/10426/1069/5577/80254/54930/5518/10383/54820/5347/9662/55142/23332/1453/9793/8481/93323/7280/1778 55 Murine_minute_virus R-HSA-5696395 Formation of Incision Complex in GG-NER 33/2393 43/10654 5.636746025289647e-14 5.636746025289647e-13 2.9667084343629717e-13 6118/902/404672/6613/7507/7336/2072/7316/4331/2966/6119/7341/1642/2965/142/2068/2071/1069/7329/6233/2067/2968/7311/2967/5887/6117/7334/10038/1022/5886/7508/7314/8451 33 Murine_minute_virus R-HSA-8953897 Cellular responses to external stimuli 182/2393 493/10654 6.695230172164558e-14 6.645635874592968e-13 3.497703091891036e-13 1017/23165/3303/7014/6118/84617/4928/55846/1019/5684/5903/5601/2077/4790/5606/9631/9448/246184/112399/7531/7290/7027/1029/1915/1783/7321/5707/2146/10111/475/84962/4502/6045/8697/10382/57690/5594/3308/347688/84335/23677/1027/80012/10049/58528/10294/3091/830/7013/7277/348995/1051/10013/50488/545/79023/472/10381/57122/5705/23636/10197/3313/1780/7001/23511/7323/1781/7316/2114/1869/5695/890/3305/8655/6774/5970/1639/9261/9532/832/5714/2289/23279/4927/7415/1871/8994/51433/79902/64223/4194/1031/7322/6119/26353/5598/9883/5928/1432/2932/5701/10524/1387/4683/57805/23225/112398/3309/347733/5708/3320/65057/5686/2033/23512/1021/10376/6009/51143/3301/7428/192669/7157/8900/51529/6648/8086/7324/10963/64682/29945/10393/22824/5609/8131/6233/51434/3326/2475/1032/3306/51343/6196/7311/9972/2034/57634/10383/23411/8021/55662/6117/5599/6396/648/3304/3312/26523/3456/5052/6416/54386/96459/3569/57521/55746/55466/140735/7280/8480/768/10728/7296/7314/51164/996/6015/5595/4193/1778/23043 182 Murine_minute_virus R-HSA-69306 DNA Replication 67/2393 127/10654 7.354855833597753e-14 7.246696188986022e-13 3.814050625782116e-13 8454/1017/4172/6118/2237/5684/8318/246184/1763/7321/5707/57804/8317/8697/5982/6500/54107/4173/5705/10197/3978/7316/5422/1869/5695/890/5425/84515/5714/5111/56655/5426/4171/1871/51433/51053/6119/5701/10926/5427/6502/5708/5985/5686/990/81620/8900/51529/5984/7324/64682/29945/10393/6233/51434/51343/7311/23649/5983/6117/5001/5981/10714/5424/4176/7314/996 67 Murine_minute_virus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 26/2393 30/10654 1.2880829456729573e-13 1.2598767497823085e-12 6.63093026201215e-13 6118/57804/56852/5982/54107/7316/5425/5111/56655/5426/6119/5427/1642/5985/7398/5984/57599/6233/7311/5983/6117/5981/10714/5424/7314/8451 26 Murine_minute_virus R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 23/2393 25/10654 2.0680213217322361e-13 1.9996094889585277e-12 1.0524260468202775e-12 1017/994/902/2305/51400/9133/891/993/890/4331/983/5519/9088/995/5520/8900/7514/5518/5347/7465/1022/5515/5516 23 Murine_minute_virus R-HSA-167287 HIV elongation arrest and recovery 29/2393 36/10654 2.0891442421954767e-13 1.9996094889585277e-12 1.0524260468202775e-12 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/7469/5435/5433/9150/2962/5437/8812/905/5439/6827/1025/11198/904/7936/6829/51497/5432/8178/25920 29 Murine_minute_virus R-HSA-167290 Pausing and recovery of HIV elongation 29/2393 36/10654 2.0891442421954767e-13 1.9996094889585277e-12 1.0524260468202775e-12 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/7469/5435/5433/9150/2962/5437/8812/905/5439/6827/1025/11198/904/7936/6829/51497/5432/8178/25920 29 Murine_minute_virus R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 49/2393 82/10654 3.2421500312056794e-13 3.0594936914194443e-12 1.610259837589181e-12 10844/115106/22995/55559/22981/7531/11190/203068/54801/7532/1454/10382/95681/121441/7277/79441/5048/1781/23354/8655/9738/983/1639/55722/4957/5566/84131/7840/7283/3320/22919/80097/10426/1069/5577/80254/54930/5518/10383/54820/5347/9662/55142/23332/1453/9793/8481/93323/1778 49 Murine_minute_virus R-HSA-380287 Centrosome maturation 49/2393 82/10654 3.2421500312056794e-13 3.0594936914194443e-12 1.610259837589181e-12 10844/115106/22995/55559/22981/7531/11190/203068/54801/7532/1454/10382/95681/121441/7277/79441/5048/1781/23354/8655/9738/983/1639/55722/4957/5566/84131/7840/7283/3320/22919/80097/10426/1069/5577/80254/54930/5518/10383/54820/5347/9662/55142/23332/1453/9793/8481/93323/1778 49 Murine_minute_virus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 37/2393 54/10654 6.119248221498033e-13 5.734120711054101e-12 3.0179582689758427e-12 9318/6917/5434/5440/902/27339/5430/5436/404672/5441/7507/5438/5431/5435/7316/5433/4331/2966/5437/1161/1642/2965/2033/2068/5439/10987/2071/6233/2968/7311/2967/7874/1022/5432/91603/7314/8451 37 Murine_minute_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 45/2393 73/10654 6.276311543684187e-13 5.840456575372786e-12 3.0739245133540976e-12 57154/892/7027/7321/6497/10273/51592/64750/7323/8239/7316/9611/5501/9612/56937/4092/4609/4089/22938/11171/60436/23327/867/8812/7046/4088/1874/142/905/3065/9958/5499/6233/7514/7048/1025/7311/56288/25937/9110/7040/57530/904/5500/7314 45 Murine_minute_virus R-HSA-72766 Translation 119/2393 291/10654 7.398754424651221e-13 6.837469606229404e-12 3.598668213804949e-12 6158/6138/6144/6203/4736/51253/6206/8891/6194/2107/1965/6191/6166/6128/6132/1917/1938/6147/6129/1915/6217/1936/6222/1983/6176/6152/6136/64432/8667/6125/1937/6224/6146/6154/6141/10480/26986/6202/6232/1967/2935/6134/6747/6169/6160/6731/6164/6155/6175/6218/6728/64963/9669/60559/6209/6193/6729/6210/6229/6231/11224/6205/6165/6130/8890/64968/6142/11222/6167/6204/8663/6228/23521/8894/5018/1981/6156/6235/6143/1973/6181/6124/6207/1977/6139/8893/90480/6233/1975/55168/7311/6223/25873/8664/3646/51386/6730/3921/6188/6189/26589/10102/6135/6201/1978/6161/9045/6187/6168/6208/6157/6137/7284/8892/1974/6122/6133/1968/6230 119 Murine_minute_virus R-HSA-176187 Activation of ATR in response to replication stress 29/2393 37/10654 7.587504560470171e-13 6.963874048650705e-12 3.665196867710897e-12 1017/4172/6118/8318/5883/8317/5982/63967/4173/545/993/84515/4171/6119/3364/10926/144715/5985/990/995/84126/1111/5984/5983/6117/5001/5884/5810/4176 29 Murine_minute_virus R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 22/2393 24/10654 8.538858548440618e-13 7.783721397898251e-12 4.096695472578027e-12 6118/2237/1763/57804/5982/54107/3978/5422/5425/5111/56655/5426/6119/5427/5985/5984/23649/5983/6117/5981/10714/5424 22 Murine_minute_virus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 43/2393 69/10654 1.1983331697148543e-12 1.0849773293364221e-11 5.710406996507485e-12 23165/3303/6118/4928/5903/9631/7531/5594/3308/10049/348995/545/79023/472/57122/23636/3313/23511/3305/9261/9532/23279/4927/79902/6119/9883/2932/57805/23225/3309/8086/22824/3306/9972/23411/8021/6117/6396/3304/3312/55746/8480/5595 43 Murine_minute_virus R-HSA-69239 Synthesis of DNA 62/2393 119/10654 1.306891731164875e-12 1.1753254495039816e-11 6.185923418442008e-12 8454/1017/4172/6118/2237/5684/8318/246184/1763/7321/5707/57804/8697/5982/6500/54107/4173/5705/10197/3978/7316/5422/5695/890/5425/84515/5714/5111/56655/5426/4171/51433/6119/5701/5427/6502/5708/5985/5686/990/81620/8900/51529/5984/7324/64682/29945/10393/6233/51434/51343/7311/23649/5983/6117/5001/5981/10714/5424/4176/7314/996 62 Murine_minute_virus R-HSA-6803529 FGFR2 alternative splicing 23/2393 26/10654 1.4096712531728151e-12 1.2593063195010482e-11 6.6279279973739375e-12 2963/5434/5440/23543/5430/5436/3178/5441/5438/5431/5435/4686/5433/3185/2962/5437/4670/5439/3187/7073/5432/22916/5725 23 Murine_minute_virus R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 20/2393 21/10654 1.6604631829236507e-12 1.4735236192832398e-11 7.755387469911787e-12 6118/2237/328/57804/5982/54107/3978/5425/5111/56655/5426/6119/5427/5985/5984/5983/6117/5981/10714/5424 20 Murine_minute_virus R-HSA-983169 Class I MHC mediated antigen processing & presentation 142/2393 371/10654 1.949731679481209e-12 1.718842401647908e-11 9.046538956041622e-12 8454/23643/57154/1147/3135/197131/8945/10293/5684/79754/6737/8065/114088/142678/246184/51320/387522/3107/7321/5707/991/84231/10273/65264/9021/10484/8697/26235/10802/9817/9039/223082/154881/821/6500/811/10533/2209/5705/26259/10333/10197/53339/7099/8517/7336/4615/79876/26263/64750/51619/9690/9554/7326/7323/10517/57630/7316/5695/7317/80196/22872/7335/7096/567/4734/5714/27252/51444/8651/3106/26118/51433/25831/7322/64219/10489/23327/9867/5701/9341/63893/6502/118424/10616/929/3309/5708/5686/55294/10422/9632/7428/22954/83737/51529/7324/63891/10075/64682/29945/9246/10393/80176/8924/51191/6233/9520/51434/90025/7327/3685/25793/51343/7311/9871/26091/6047/3133/7318/3134/54461/80204/26232/57520/6396/27338/7334/55182/7097/4591/3551/26268/7332/3105/997/10427/9820/7314/642/996/899 142 Murine_minute_virus R-HSA-168253 Host Interactions with Influenza Factors 31/2393 42/10654 2.0065154557896577e-12 1.7573403338288508e-11 9.249159651730791e-12 3839/23165/4928/3837/3838/5903/9631/8106/348995/9636/79023/57122/23636/23511/293/23279/4927/79902/10898/3840/9883/23225/8086/3836/9972/5610/8021/7040/6396/55746/8480 31 Murine_minute_virus R-HSA-9006925 Intracellular signaling by second messengers 122/2393 305/10654 2.33014672425855e-12 2.027530266562634e-11 1.0671211929277023e-11 1147/2308/5170/27161/3643/3838/5684/8841/5335/2309/90865/5468/5525/1822/5575/23186/1459/5707/5567/23239/2146/5526/9112/10273/207/6045/5578/57690/5594/4303/84335/1027/7249/80012/58528/1460/112/3708/2064/5705/10197/4615/5573/5528/2100/7316/5695/1457/8658/4734/50852/10768/5714/10645/6714/2099/1108/10818/64223/5566/81847/10014/5519/5928/2932/5701/57459/5576/29851/3164/5708/54815/5686/23512/391/5728/6009/5529/6615/192669/3066/3065/7157/1107/2066/23028/5613/5987/3654/7189/5371/5577/6233/5527/2885/79109/2475/8660/1385/57504/7311/2931/5518/1386/3710/1956/331/8394/648/26523/80351/7874/5781/57521/23252/7314/6015/253260/5595/4193/5515/5516 122 Murine_minute_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 25/2393 30/10654 2.366361049406929e-12 2.0457572943259902e-11 1.0767143654347317e-11 7124/1147/7186/56957/6885/8737/55072/23118/27005/8517/7316/7128/7132/329/9099/10616/10454/6233/7311/331/8717/1540/3551/7185/7314 25 Murine_minute_virus R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 27/2393 34/10654 2.7271440529941122e-12 2.3276261344026184e-11 1.2250663865276939e-11 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/7469/5435/5433/9150/2962/5437/5439/6827/1025/11198/904/7936/6829/51497/5432/8178/25920 27 Murine_minute_virus R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 27/2393 34/10654 2.7271440529941122e-12 2.3276261344026184e-11 1.2250663865276939e-11 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/7469/5435/5433/9150/2962/5437/5439/6827/1025/11198/904/7936/6829/51497/5432/8178/25920 27 Murine_minute_virus R-HSA-4615885 SUMOylation of DNA replication proteins 32/2393 45/10654 4.677584667893795e-12 3.9670654778339785e-11 2.0879291988599882e-11 23165/7150/5905/4928/5903/55143/9631/9212/51588/3619/348995/79023/6613/57122/23636/332/23511/6790/5111/23279/4927/79902/9883/7341/23225/8086/7329/9972/8021/6396/55746/8480 32 Murine_minute_virus R-HSA-937041 IKK complex recruitment mediated by RIP1 22/2393 25/10654 5.599166487763547e-12 4.7187943984925496e-11 2.4835759992066045e-11 23643/1147/387522/7321/8737/7099/8517/7323/7316/7335/7322/329/100302736/929/7189/6233/7311/353376/7334/3551/7314/148022 22 Murine_minute_virus R-HSA-5620912 Anchoring of the basal body to the plasma membrane 53/2393 98/10654 8.435453921656349e-12 7.064692659387192e-11 3.7182592944143116e-11 115106/22995/55559/22981/7531/54903/80776/11190/203068/54801/7532/1454/10382/95681/121441/7277/79441/5048/1781/23354/8655/9738/79598/983/1639/55722/4957/5566/132320/84131/7840/7283/3320/22919/1069/5577/80254/26005/54930/5518/10383/54820/5347/9662/55142/23332/1453/9793/8481/57787/93323/9657/1778 53 Murine_minute_virus R-HSA-2132295 MHC class II antigen presentation 62/2393 123/10654 8.564313401382244e-12 7.12806208562249e-11 3.751611624011836e-11 3831/3120/114876/1173/84617/164/162/6712/1783/3117/3119/10484/10382/10802/1174/347688/1785/821/830/3123/7277/10381/160/3113/1780/3115/1781/3122/1509/22872/8655/1639/832/5641/3796/10112/1062/10437/347733/10376/51143/9632/11004/163/9871/3799/1213/10383/1211/84643/3127/8905/6396/81930/7879/140735/8907/7280/10427/1508/51164/1778 62 Murine_minute_virus R-HSA-448424 Interleukin-17 signaling 43/2393 72/10654 9.425938499730804e-12 7.796763944221775e-11 4.10355997064304e-11 8454/1147/8945/1326/5601/4790/6885/5606/5604/387522/1849/5594/6500/23118/8517/5528/7316/79155/7335/4205/9261/5519/5598/1432/3656/10454/3654/7189/5609/6233/1385/6196/7311/5518/1386/5599/7334/3551/6416/7314/5595/5515/5516 43 Murine_minute_virus R-HSA-1257604 PIP3 activates AKT signaling 107/2393 264/10654 2.087414204414872e-11 1.7160337631386067e-10 9.031756648097928e-11 1147/2308/5170/27161/3643/5684/8841/2309/90865/5468/5525/1822/23186/1459/5707/23239/2146/5526/9112/10273/207/6045/57690/5594/4303/84335/1027/7249/80012/58528/1460/2064/5705/10197/4615/5528/2100/7316/5695/1457/8658/4734/50852/5714/6714/2099/1108/10818/64223/81847/10014/5519/5928/2932/5701/57459/29851/3164/5708/54815/5686/23512/391/5728/6009/5529/6615/192669/3066/3065/7157/1107/2066/23028/5987/3654/7189/5371/6233/5527/2885/79109/2475/8660/1385/57504/7311/2931/5518/1386/1956/331/8394/648/26523/80351/7874/5781/57521/23252/7314/6015/253260/5595/4193/5515/5516 107 Murine_minute_virus R-HSA-168276 NS1 Mediated Effects on Host Pathways 29/2393 40/10654 2.2009595205988344e-11 1.7983449741478278e-10 9.464973548146464e-11 3839/23165/4928/3837/3838/5903/9631/8106/348995/9636/79023/57122/23636/23511/23279/4927/79902/10898/3840/9883/23225/8086/3836/9972/5610/8021/6396/55746/8480 29 Murine_minute_virus R-HSA-5689896 Ovarian tumor domain proteases 28/2393 38/10654 2.5813631498060338e-11 2.0963797701455063e-10 1.1033577737607927e-10 56957/7321/8737/57506/7706/8517/7316/79155/983/2099/79589/7415/23586/7128/324/64135/5728/7157/7189/6233/7311/55593/84282/78990/7187/10318/23252/7314 28 Murine_minute_virus R-HSA-110373 Resolution of AP sites via the multiple-nucleotide patch replacement pathway 22/2393 26/10654 2.864139027801256e-11 2.3120158417190858e-10 1.2168504430100454e-10 6118/2237/328/57804/5982/54107/3978/5425/5111/56655/5426/6119/5427/5985/142/5984/5983/6117/5981/10038/10714/5424 22 Murine_minute_virus R-HSA-177243 Interactions of Rev with host cellular proteins 27/2393 36/10654 2.946653592326491e-11 2.364380726776945e-10 1.244410908829971e-10 23165/5905/4928/3837/5903/9631/4869/348995/79023/57122/23636/23511/23279/4927/79902/9883/23225/5902/5901/8086/7514/9972/8021/6396/1104/55746/8480 27 Murine_minute_virus R-HSA-6807505 RNA polymerase II transcribes snRNA genes 43/2393 74/10654 3.3660120723498636e-11 2.6847953434219153e-10 1.4130501807483765e-10 6884/2963/5434/5440/5430/5436/5451/26512/79871/5441/5438/5431/5435/4686/5433/58490/2962/29101/51808/5437/8812/25896/23248/129685/905/64859/5439/6827/80789/1025/10302/51593/6619/79035/904/6829/2961/65123/1022/5432/22916/6618/8178 43 Murine_minute_virus R-HSA-400253 Circadian Clock 41/2393 70/10654 6.819503679078633e-11 5.40718043193217e-10 2.845884437859037e-10 8454/5187/8945/8841/1374/79718/5936/10135/8204/1454/1407/6500/3091/200186/1408/6720/4209/7316/9611/5469/5501/64784/1387/150094/6907/1390/2033/79365/6256/5499/6233/1385/7311/10499/1386/23411/1453/23373/5500/96764/7314 41 Murine_minute_virus R-HSA-5654738 Signaling by FGFR2 42/2393 73/10654 8.853760958579867e-11 6.978846873233543e-10 3.673077301701864e-10 2963/5434/5440/6464/23543/5335/5430/5436/5594/3178/5441/5438/5431/5435/4686/7316/5433/3185/6714/10818/8569/2962/867/5437/4670/5439/6233/2885/3187/7073/7311/5518/3845/3265/5781/5432/22916/5725/7314/5595/5515/5516 42 Murine_minute_virus R-HSA-5357905 Regulation of TNFR1 signaling 25/2393 33/10654 1.1204347318231606e-10 8.780014857561609e-10 4.6210604513482153e-10 7124/1147/7186/56957/8737/55072/841/27005/8517/8887/7316/7128/7132/329/9099/10616/8567/6233/7311/331/8717/1540/3551/7185/7314 25 Murine_minute_virus R-HSA-69231 Cyclin D associated events in G1 30/2393 44/10654 1.1762796761238691e-10 9.111068011595287e-10 4.795298953471204e-10 8454/25/1019/902/7027/1029/1027/6500/7316/1869/5753/4331/6714/1871/1031/5519/4067/6502/1021/1874/595/5520/6233/1032/7311/5518/1022/7314/5515/5516 30 Murine_minute_virus R-HSA-69236 G1 Phase 30/2393 44/10654 1.1762796761238691e-10 9.111068011595287e-10 4.795298953471204e-10 8454/25/1019/902/7027/1029/1027/6500/7316/1869/5753/4331/6714/1871/1031/5519/4067/6502/1021/1874/595/5520/6233/1032/7311/5518/1022/7314/5515/5516 30 Murine_minute_virus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 17/2393 18/10654 1.2808210055922888e-10 9.863793951113029e-10 5.191470500585804e-10 23643/3665/29110/7099/7316/100302736/929/3661/6233/10010/7311/7187/9641/353376/5781/7314/148022 17 Murine_minute_virus R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 15/2393 15/10654 1.805666893110569e-10 1.336792064512797e-9 7.035747707962087e-10 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Murine_minute_virus R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 15/2393 15/10654 1.805666893110569e-10 1.336792064512797e-9 7.035747707962087e-10 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Murine_minute_virus R-HSA-5358508 Mismatch Repair 15/2393 15/10654 1.805666893110569e-10 1.336792064512797e-9 7.035747707962087e-10 6118/4436/9156/57804/2956/4292/3978/5425/5111/5395/6119/6117/10714/5424/4437 15 Murine_minute_virus R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 15/2393 15/10654 1.805666893110569e-10 1.336792064512797e-9 7.035747707962087e-10 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Murine_minute_virus R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 15/2393 15/10654 1.805666893110569e-10 1.336792064512797e-9 7.035747707962087e-10 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Murine_minute_virus R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 15/2393 15/10654 1.805666893110569e-10 1.336792064512797e-9 7.035747707962087e-10 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Murine_minute_virus R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 15/2393 15/10654 1.805666893110569e-10 1.336792064512797e-9 7.035747707962087e-10 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Murine_minute_virus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 27/2393 38/10654 2.326235211255325e-10 1.7127226280671072e-9 9.014329621405829e-10 23165/4928/5903/9631/51588/348995/79023/57122/23636/23511/23279/4927/79902/9883/7341/23225/7428/8086/7329/5987/5371/9972/8021/6396/55746/8480/4193 27 Murine_minute_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 18/2393 20/10654 2.3797338732991326e-10 1.733067059902629e-9 9.12140557843489e-10 1147/387522/7321/8737/8517/7098/7323/7316/7335/7322/329/7189/6233/7311/7334/3551/7314/148022 18 Murine_minute_virus R-HSA-69186 Lagging Strand Synthesis 18/2393 20/10654 2.3797338732991326e-10 1.733067059902629e-9 9.12140557843489e-10 6118/2237/1763/57804/5982/3978/5422/5425/5111/6119/5985/5984/23649/5983/6117/5981/10714/5424 18 Murine_minute_virus R-HSA-2980766 Nuclear Envelope Breakdown 33/2393 52/10654 2.53704666327453e-10 1.8376446101556054e-9 9.671813737661081e-10 4000/23165/4928/5903/9631/91754/5578/140609/348995/79023/9133/57122/23636/7443/23511/891/983/23279/4927/79902/9883/23225/8086/64900/23399/23592/23175/9972/5347/8021/6396/55746/8480 33 Murine_minute_virus R-HSA-159227 Transport of the SLBP independent Mature mRNA 25/2393 34/10654 3.3285067768783365e-10 2.3851331984047973e-9 1.2553332623183144e-9 23165/4928/5903/9631/348995/79023/57122/23636/23511/4686/23279/4927/79902/9883/23225/10189/10482/8086/1977/9972/8021/6396/55746/22916/8480 25 Murine_minute_virus R-HSA-165054 Rev-mediated nuclear export of HIV RNA 25/2393 34/10654 3.3285067768783365e-10 2.3851331984047973e-9 1.2553332623183144e-9 23165/5905/4928/5903/9631/348995/79023/57122/23636/23511/23279/4927/79902/9883/23225/5902/5901/8086/7514/9972/8021/6396/1104/55746/8480 25 Murine_minute_virus R-HSA-75893 TNF signaling 29/2393 43/10654 3.617364738954954e-10 2.5783344415955525e-9 1.3570181271555536e-9 7124/1147/7186/56957/6885/8737/55072/23118/841/27005/8517/8887/7316/7128/7132/329/9099/10616/10454/8567/6233/7311/8772/331/8717/1540/3551/7185/7314 29 Murine_minute_virus R-HSA-69190 DNA strand elongation 24/2393 32/10654 3.820300404780379e-10 2.708572773759634e-9 1.4255646177682283e-9 4172/6118/2237/8318/1763/57804/5982/4173/3978/5422/5425/84515/5111/4171/6119/5985/5984/23649/5983/6117/5981/10714/5424/4176 24 Murine_minute_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 21/2393 26/10654 4.457367265122642e-10 3.143616913297021e-9 1.654535217524748e-9 57154/10273/64750/7316/5501/56937/4092/11171/23327/7046/4088/9958/5499/6233/7514/7048/7311/9110/7040/5500/7314 21 Murine_minute_virus R-HSA-191859 snRNP Assembly 33/2393 53/10654 5.278292035303194e-10 3.6838079829720207e-9 1.938846306827379e-9 23165/4928/6606/5903/11218/9631/8487/348995/79023/57122/23636/10073/23511/4686/23279/4927/79902/9883/51808/23225/1207/79084/8086/9972/6634/8021/6396/55746/22916/8480/6628/96764/79760 33 Murine_minute_virus R-HSA-194441 Metabolism of non-coding RNA 33/2393 53/10654 5.278292035303194e-10 3.6838079829720207e-9 1.938846306827379e-9 23165/4928/6606/5903/11218/9631/8487/348995/79023/57122/23636/10073/23511/4686/23279/4927/79902/9883/51808/23225/1207/79084/8086/9972/6634/8021/6396/55746/22916/8480/6628/96764/79760 33 Murine_minute_virus R-HSA-196299 Beta-catenin phosphorylation cascade 16/2393 17/10654 5.418255418569742e-10 3.723313979940233e-9 1.9596389368106487e-9 1499/5525/139285/5526/1452/5528/23401/5519/2932/324/8312/5529/5527/5518/5515/5516 16 Murine_minute_virus R-HSA-5655862 Translesion synthesis by POLK 16/2393 17/10654 5.418255418569742e-10 3.723313979940233e-9 1.9596389368106487e-9 6118/5982/7316/5111/10459/6119/51455/5985/5984/6233/51426/7311/5983/6117/5981/7314 16 Murine_minute_virus R-HSA-5656121 Translesion synthesis by POLI 16/2393 17/10654 5.418255418569742e-10 3.723313979940233e-9 1.9596389368106487e-9 6118/5982/7316/11201/5111/10459/6119/51455/5985/5984/6233/7311/5983/6117/5981/7314 16 Murine_minute_virus R-HSA-73933 Resolution of Abasic Sites (AP sites) 27/2393 39/10654 5.942388730669356e-10 4.04265734279557e-9 2.1277143909450367e-9 11284/6118/2237/328/57804/7515/5982/54107/23583/3978/6996/5425/5111/56655/5426/6119/5427/5985/142/5984/5983/6117/5981/10038/3980/10714/5424 27 Murine_minute_virus R-HSA-70171 Glycolysis 40/2393 71/10654 5.943309675602442e-10 4.04265734279557e-9 2.1277143909450367e-9 23165/4928/7167/5903/2597/9631/5315/5567/348995/79023/57122/23636/5214/83440/23511/5528/5230/23279/4927/79902/5566/5519/9883/2023/5209/226/23225/5208/5224/8086/5213/9972/5518/8021/6396/55746/8480/5515/5223/5516 40 Murine_minute_virus R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 14/2393 14/10654 8.075786356745046e-10 5.253181416523476e-9 2.76483232448604e-9 5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 14 Murine_minute_virus R-HSA-4839744 truncated APC mutants destabilize the destruction complex 14/2393 14/10654 8.075786356745046e-10 5.253181416523476e-9 2.76483232448604e-9 5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 14 Murine_minute_virus R-HSA-4839748 AMER1 mutants destabilize the destruction complex 14/2393 14/10654 8.075786356745046e-10 5.253181416523476e-9 2.76483232448604e-9 5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 14 Murine_minute_virus R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 14/2393 14/10654 8.075786356745046e-10 5.253181416523476e-9 2.76483232448604e-9 6118/4436/9156/57804/2956/4292/3978/5425/5111/5395/6119/6117/10714/5424 14 Murine_minute_virus R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 14/2393 14/10654 8.075786356745046e-10 5.253181416523476e-9 2.76483232448604e-9 6118/4436/9156/57804/4292/3978/5425/5111/5395/6119/6117/10714/5424/4437 14 Murine_minute_virus R-HSA-5467337 APC truncation mutants have impaired AXIN binding 14/2393 14/10654 8.075786356745046e-10 5.253181416523476e-9 2.76483232448604e-9 5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 14 Murine_minute_virus R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 14/2393 14/10654 8.075786356745046e-10 5.253181416523476e-9 2.76483232448604e-9 5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 14 Murine_minute_virus R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 14/2393 14/10654 8.075786356745046e-10 5.253181416523476e-9 2.76483232448604e-9 5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 14 Murine_minute_virus R-HSA-918233 TRAF3-dependent IRF activation pathway 14/2393 14/10654 8.075786356745046e-10 5.253181416523476e-9 2.76483232448604e-9 3665/80143/29110/57506/7706/23586/1387/2033/64135/3661/84282/7187/9641/3456 14 Murine_minute_virus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 29/2393 44/10654 8.336795860428428e-10 5.396766402402944e-9 2.8404033696857596e-9 892/7027/7321/6497/51592/64750/7323/8239/7316/9611/9612/4092/4609/4089/22938/60436/23327/8812/4088/1874/142/905/3065/6233/1025/7311/25937/904/7314 29 Murine_minute_virus R-HSA-909733 Interferon alpha/beta signaling 39/2393 69/10654 8.555250663578312e-10 5.5115557159591056e-9 2.900818797873213e-9 3135/3665/51447/10379/3107/10410/9021/4600/9636/8638/2634/3662/3394/3663/3664/103/3434/6772/8651/3659/3106/25939/4939/6059/3454/3661/4599/684/3716/3133/3134/4940/3437/3456/6773/4938/5781/3105/3660 39 Murine_minute_virus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 25/2393 35/10654 9.161975303592395e-10 5.846212812768481e-9 3.076954111983411e-9 23165/4928/5903/9631/348995/79023/57122/23636/23511/4686/23279/4927/79902/9883/23225/10189/10482/8086/1977/9972/8021/6396/55746/22916/8480 25 Murine_minute_virus R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 25/2393 35/10654 9.161975303592395e-10 5.846212812768481e-9 3.076954111983411e-9 23165/4928/5903/9631/91754/140609/348995/79023/9133/57122/23636/23511/891/983/23279/4927/79902/9883/23225/8086/9972/8021/6396/55746/8480 25 Murine_minute_virus R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 24/2393 33/10654 1.1019942199333042e-9 6.965435163729376e-9 3.6660185072259873e-9 23165/3303/4928/5903/9631/348995/79023/57122/23636/23511/23279/4927/79902/9883/23225/5901/8086/7514/9972/8021/6396/3304/55746/8480 24 Murine_minute_virus R-HSA-180746 Nuclear import of Rev protein 24/2393 33/10654 1.1019942199333042e-9 6.965435163729376e-9 3.6660185072259873e-9 23165/4928/3837/5903/9631/4869/348995/79023/57122/23636/23511/23279/4927/79902/9883/23225/5901/8086/9972/8021/6396/1104/55746/8480 24 Murine_minute_virus R-HSA-5688426 Deubiquitination 112/2393 297/10654 1.2464819263790395e-009 7.841717283323535e-9 4.127219622801861e-9 23358/10600/5684/3607/23326/221937/7186/56957/6885/90865/7321/5707/991/8737/8237/9817/57506/4303/10445/51720/91833/63967/409/4086/1080/3091/5705/4287/55031/27005/10197/7706/8517/64750/580/29086/8239/7316/993/5695/79155/890/4792/9738/8658/983/11047/55252/5714/4092/8678/2099/9100/4609/79589/7415/4194/23586/4089/81847/27430/7128/29844/5701/9097/329/7046/6502/7347/9099/4088/8078/5708/5686/324/2033/64135/5728/8312/10454/8473/7157/8900/10869/9958/63891/7189/57599/6233/672/7048/9804/7311/55593/84282/79184/78990/7187/10318/7040/8607/5887/1540/9736/80351/7874/10254/5886/23252/7314/4193/7528 112 Murine_minute_virus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 18/2393 21/10654 1.3138876323850341e-9 8.2271468569904e-9 4.330077293152842e-9 1147/4790/8737/29110/23220/147945/8517/4615/7098/5970/4792/4793/1660/3661/81030/3551/4791/148022 18 Murine_minute_virus R-HSA-167161 HIV Transcription Initiation 30/2393 47/10654 1.3594458120909457e-9 8.242793611773154e-9 4.338312427249029e-9 6884/2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/5433/6872/4331/8148/2966/2962/5437/2965/2068/5439/2071/6873/2968/2967/6883/2961/1022/5432 30 Murine_minute_virus R-HSA-167162 RNA Polymerase II HIV Promoter Escape 30/2393 47/10654 1.3594458120909457e-9 8.242793611773154e-9 4.338312427249029e-9 6884/2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/5433/6872/4331/8148/2966/2962/5437/2965/2068/5439/2071/6873/2968/2967/6883/2961/1022/5432 30 Murine_minute_virus R-HSA-4570464 SUMOylation of RNA binding proteins 30/2393 47/10654 1.3594458120909457e-9 8.242793611773154e-9 4.338312427249029e-9 23165/4928/5903/9631/6045/80012/348995/51602/79023/6613/57122/23636/3183/23511/3190/23279/4927/79902/9883/7341/23225/8086/7329/9972/8021/6396/648/55746/8480/6015 30 Murine_minute_virus R-HSA-73776 RNA Polymerase II Promoter Escape 30/2393 47/10654 1.3594458120909457e-9 8.242793611773154e-9 4.338312427249029e-9 6884/2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/5433/6872/4331/8148/2966/2962/5437/2965/2068/5439/2071/6873/2968/2967/6883/2961/1022/5432 30 Murine_minute_virus R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 30/2393 47/10654 1.3594458120909457e-9 8.242793611773154e-9 4.338312427249029e-9 6884/2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/5433/6872/4331/8148/2966/2962/5437/2965/2068/5439/2071/6873/2968/2967/6883/2961/1022/5432 30 Murine_minute_virus R-HSA-75953 RNA Polymerase II Transcription Initiation 30/2393 47/10654 1.3594458120909457e-9 8.242793611773154e-9 4.338312427249029e-9 6884/2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/5433/6872/4331/8148/2966/2962/5437/2965/2068/5439/2071/6873/2968/2967/6883/2961/1022/5432 30 Murine_minute_virus R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 30/2393 47/10654 1.3594458120909457e-9 8.242793611773154e-9 4.338312427249029e-9 6884/2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/5433/6872/4331/8148/2966/2962/5437/2965/2068/5439/2071/6873/2968/2967/6883/2961/1022/5432 30 Murine_minute_virus R-HSA-72165 mRNA Splicing - Minor Pathway 32/2393 52/10654 1.4846527152155383e-9 8.961417290039735e-9 4.716535415810387e-9 2963/5434/5440/6432/6431/24148/5430/4904/5436/11325/23450/5441/5438/5431/5435/10594/4686/5433/9343/9416/2962/5437/5439/9410/6634/6427/6426/5432/22916/10992/10262/6628 32 Murine_minute_virus R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 33/2393 55/10654 2.0918451978639153e-9 1.2569832130662092e-8 6.615701121401101e-9 3303/84617/1783/10382/347688/10294/830/7277/10381/1780/1781/3305/8655/1639/832/2289/347733/3320/10376/51143/3301/10963/3326/3306/10383/3304/3312/55466/140735/7280/10728/51164/1778 33 Murine_minute_virus R-HSA-110312 Translesion synthesis by REV1 15/2393 16/10654 2.283670487222475e-9 1.3540347136628834e-8 7.126498492962544e-9 6118/5982/7316/5111/10459/6119/51455/5985/5984/6233/7311/5983/6117/5981/7314 15 Murine_minute_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 15/2393 16/10654 2.283670487222475e-9 1.3540347136628834e-8 7.126498492962544e-9 8454/1147/8945/1326/4790/5604/6500/8517/7316/79155/6233/7311/3551/6416/7314 15 Murine_minute_virus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 15/2393 16/10654 2.283670487222475e-9 1.3540347136628834e-8 7.126498492962544e-9 23643/6885/23118/7099/7316/100302736/929/3656/10454/7189/6233/7311/353376/7314/148022 15 Murine_minute_virus R-HSA-6807070 PTEN Regulation 63/2393 140/10654 2.3361273202661527e-9 1.3790355106416937e-8 7.258081634956282e-9 27161/5684/8841/5468/1822/23186/1459/5707/2146/9112/10273/207/6045/57690/5594/80012/58528/1460/5705/10197/7316/5695/1457/8658/4734/5714/1108/64223/81847/10014/5928/5701/57459/5708/54815/5686/23512/5728/6009/6615/192669/3066/3065/7157/1107/23028/5987/5371/6233/2475/57504/7311/1386/331/648/26523/80351/7874/57521/23252/7314/6015/5595 63 Murine_minute_virus R-HSA-4085377 SUMOylation of SUMOylation proteins 24/2393 34/10654 2.947938721322433e-9 1.732560476566693e-8 9.118739350351017e-9 23165/4928/5903/9631/51588/348995/79023/6613/57122/23636/23511/23279/4927/79902/9883/7341/23225/8086/7329/9972/8021/6396/55746/8480 24 Murine_minute_virus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 27/2393 41/10654 3.309044647204024e-9 1.936296867796241e-8 1.0191036146296005e-8 23165/4928/5903/9631/348995/79023/57122/23636/23511/81608/4686/23279/4927/79902/10898/9883/23225/10189/10482/8086/1977/9972/8021/6396/55746/22916/8480 27 Murine_minute_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 23/2393 32/10654 3.608806206796094e-9 2.0945133164837954e-8 1.1023754297283133e-8 57154/10273/64750/7316/5501/56937/4092/4089/11171/23327/867/7046/4088/9958/5499/6233/7514/7048/7311/9110/7040/5500/7314 23 Murine_minute_virus R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13/2393 13/10654 3.6106908664757966e-9 2.0945133164837954e-8 1.1023754297283133e-8 7531/7532/10971/7533/2810/11200/7534/891/983/995/1111/7465/7529 13 Murine_minute_virus R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 40/2393 75/10654 5.226128675163301e-9 3.0185398382408724e-8 1.5887051780215115e-8 10921/23165/7919/4928/5903/6432/6431/6430/9631/6428/348995/79023/57122/23636/22794/23511/4686/29107/65109/84321/23279/4927/79902/9883/10569/23225/10189/9295/10482/8086/9972/8021/9775/6396/6427/2733/6426/55746/22916/8480 40 Murine_minute_virus R-HSA-5260271 Diseases of Immune System 19/2393 24/10654 5.815926411118438e-9 3.330487773888336e-8 1.7528883020464925e-8 23643/1147/81793/4790/10333/7099/8517/4615/7098/5970/4792/7096/929/81622/7187/7097/3551/4791/148022 19 Murine_minute_virus R-HSA-5602358 Diseases associated with the TLR signaling cascade 19/2393 24/10654 5.815926411118438e-9 3.330487773888336e-8 1.7528883020464925e-8 23643/1147/81793/4790/10333/7099/8517/4615/7098/5970/4792/7096/929/81622/7187/7097/3551/4791/148022 19 Murine_minute_virus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 27/2393 42/10654 7.284632656756332e-9 4.142375848179663e-8 2.1801978148314015e-8 23165/4928/5903/9631/348995/79023/57122/23636/23511/81608/4686/23279/4927/79902/10898/9883/23225/10189/10482/8086/1977/9972/8021/6396/55746/22916/8480 27 Murine_minute_virus R-HSA-72202 Transport of Mature Transcript to Cytoplasm 43/2393 84/10654 7.295527613211944e-9 4.142375848179663e-8 2.1801978148314015e-8 10921/23165/7919/4928/5903/6432/6431/6430/9631/6428/348995/79023/57122/23636/22794/23511/81608/4686/29107/65109/84321/23279/4927/79902/10898/9883/10569/23225/10189/9295/10482/8086/1977/9972/8021/9775/6396/6427/2733/6426/55746/22916/8480 43 Murine_minute_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 14/2393 15/10654 9.58574588476277e-9 5.419788812481904e-8 2.8525204276220546e-8 54106/3665/387522/4615/7316/7335/3654/7189/6233/51311/7311/7334/51284/7314 14 Murine_minute_virus R-HSA-5675221 Negative regulation of MAPK pathway 26/2393 40/10654 9.83056239819765e-9 5.5348544594894335e-8 2.9130812944681226e-8 5604/5525/5526/8844/1849/5594/5528/7316/5605/5519/5529/5894/6233/5527/7311/5518/5536/4140/3845/3265/369/7529/7314/5595/5515/5516 26 Murine_minute_virus R-HSA-9006936 Signaling by TGF-beta family members 49/2393 102/10654 1.0215955330096838e-8 5.727774118129608e-8 3.01461795691032e-8 57154/10272/892/7027/7321/6497/10273/4086/51592/64750/7323/8239/7316/9611/5501/9612/56937/4092/4609/4089/22938/11171/60436/23327/867/8812/7046/4088/1874/142/905/3065/9958/5499/657/6233/7514/7048/1025/7311/56288/25937/9110/7040/57530/904/5500/4090/7314 49 Murine_minute_virus R-HSA-162909 Host Interactions of HIV factors 58/2393 129/10654 1.0429288141938376e-8 5.8230192125822596e-8 3.0647469539906626e-8 23165/5905/8945/1173/4928/3837/164/5684/5903/8065/162/9631/5707/1174/4869/6500/348995/79023/57122/5705/23636/10197/160/23511/7316/293/5695/292/567/5714/23279/4927/79902/9883/5701/23225/5708/5686/5902/5901/8086/5478/3836/6233/7514/163/1025/7311/9972/8021/8905/6396/904/1104/55746/8907/8480/7314 58 Murine_minute_virus R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 22/2393 31/10654 1.1680680010867417e-8 6.46781455147204e-8 3.40411292182739e-8 23165/4928/3837/5903/9631/348995/79023/57122/23636/23511/23279/4927/79902/9883/23225/8086/3836/9972/8021/6396/55746/8480 22 Murine_minute_virus R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 22/2393 31/10654 1.1680680010867417e-8 6.46781455147204e-8 3.40411292182739e-8 23165/4928/5903/9631/348995/79023/57122/23636/23511/23279/4927/79902/9883/23225/5901/8086/7514/9972/8021/6396/55746/8480 22 Murine_minute_virus R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 15/2393 17/10654 1.534750757746374e-8 8.463234631193997e-8 4.454334016417893e-8 23643/6885/23118/7099/7316/100302736/929/3656/10454/7189/6233/7311/353376/7314/148022 15 Murine_minute_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 12/2393 12/10654 1.613816556112369e-8 8.826588510981937e-8 4.6455729005168084e-8 3665/29110/7098/7316/3661/6233/10010/7311/7187/9641/7314/148022 12 Murine_minute_virus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12/2393 12/10654 1.613816556112369e-8 8.826588510981937e-8 4.6455729005168084e-8 1147/8737/57506/841/7706/8517/23586/843/64135/84282/8772/3551 12 Murine_minute_virus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 19/2393 25/10654 1.9109974842649957e-8 1.0409498491524774e-7 5.4786834165919864e-8 246184/7321/991/8697/7316/4085/51433/51529/7324/64682/29945/10393/6233/51434/701/7311/9184/7314/996 19 Murine_minute_virus R-HSA-110320 Translesion Synthesis by POLH 16/2393 19/10654 1.9273091229492413e-8 1.0413686390128965e-7 5.4808875737520866e-8 6118/5982/7316/5111/7415/6119/5429/5985/5984/6233/7311/5983/6117/5981/55666/7314 16 Murine_minute_virus R-HSA-8851708 Signaling by FGFR2 IIIa TM 16/2393 19/10654 1.9273091229492413e-8 1.0413686390128965e-7 5.4808875737520866e-8 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/5439/5432/22916 16 Murine_minute_virus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 18/2393 23/10654 2.0691266919242455e-8 1.104633373377884e-7 5.8138598598836e-8 246184/7321/991/8697/7316/891/983/51433/51529/7324/64682/29945/10393/6233/51434/7311/7314/996 18 Murine_minute_virus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 18/2393 23/10654 2.0691266919242455e-8 1.104633373377884e-7 5.8138598598836e-8 7321/6497/51592/64750/7323/8239/7316/9611/9612/4089/60436/23327/4088/142/3065/6233/7311/7314 18 Murine_minute_virus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 18/2393 23/10654 2.0691266919242455e-8 1.104633373377884e-7 5.8138598598836e-8 5601/6885/387522/23118/8517/7316/7335/3656/10454/3654/7189/5609/6233/7311/5599/7334/6416/7314 18 Murine_minute_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 48/2393 101/10654 2.2276717648423412e-8 1.1845556209875941e-7 6.234503268355758e-8 8454/1147/5170/8945/5684/4773/4790/6885/387522/4772/7321/5707/5336/9039/6500/23118/10892/3708/5705/841/10197/8517/7316/5695/7335/5970/4792/6850/10768/8915/5714/6714/7322/5701/5708/5686/5534/10454/7189/6233/7311/5971/3710/7334/3551/997/4791/7314 48 Murine_minute_virus R-HSA-190236 Signaling by FGFR 43/2393 87/10654 2.8184717496468003e-8 1.492787408903839e-7 7.856775836335993e-8 2963/5434/5440/6464/23543/5335/5430/5436/5594/3178/5441/5438/5431/5435/4686/7316/5433/3185/6714/10818/8569/2962/867/5437/4670/5439/6233/2885/3187/7073/7311/5518/3845/3265/5781/5432/22916/5725/7314/161742/5595/5515/5516 43 Murine_minute_virus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 29/2393 49/10654 3.073671133933007e-8 1.6215430391615078e-7 8.53443704821846e-8 1017/7027/4849/1027/4869/4850/2810/1869/891/890/10769/983/6790/5111/1647/4848/23019/2033/995/1874/7157/8900/55571/5325/581/3276/85456/29883/1263 29 Murine_minute_virus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 111/2393 309/10654 3.3885563221134706e-8 1.780653126130216e-7 9.371858558580084e-8 8454/57154/197131/8945/10293/5684/79754/6737/8065/114088/142678/246184/51320/387522/7321/5707/991/84231/10273/65264/9021/8697/26235/9817/9039/223082/154881/6500/10533/5705/26259/10197/53339/7336/79876/26263/64750/51619/9690/7326/7323/10517/57630/7316/5695/7317/80196/7335/4734/5714/27252/51444/8651/26118/51433/25831/7322/64219/10489/23327/9867/5701/63893/6502/118424/10616/5708/5686/55294/10422/7428/22954/83737/51529/7324/63891/10075/64682/29945/9246/10393/80176/8924/51191/6233/9520/51434/90025/7327/25793/51343/7311/26091/6047/7318/54461/80204/26232/57520/27338/7334/55182/4591/26268/7332/997/9820/7314/642/996/899 111 Murine_minute_virus R-HSA-8856688 Golgi-to-ER retrograde transport 58/2393 133/10654 4.033574619643867e-8 2.1113242149698367e-7 1.111223271036756e-7 3831/84364/22820/84617/2589/5321/11014/1783/51014/10382/347688/830/7277/10381/55605/23299/1780/9554/377/5048/1781/22930/8655/1315/1639/832/25782/55738/3796/5870/9183/10112/11316/636/1062/100302736/2590/347733/10376/10972/51143/1314/11004/9276/10749/3799/10383/84643/26286/81930/26958/140735/7280/54732/51164/1778/22818/372 58 Murine_minute_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 58/2393 134/10654 5.574321919252875e-8 2.9064557866921603e-7 1.5297135719432423e-7 8454/1147/5170/8945/5684/5601/6464/4773/5335/4790/6885/387522/4772/7321/5707/5336/5594/4214/6500/23118/10892/3708/5705/10197/8517/7316/5695/7335/5970/4792/6850/10768/8915/5714/7322/5701/4067/5708/5686/5534/10454/7189/5609/6233/2885/7410/7311/9846/3710/3845/5599/7334/3265/3551/6416/997/7314/5595 58 Murine_minute_virus R-HSA-1295596 Spry regulation of FGF signaling 14/2393 16/10654 6.070027366754459e-8 3.152649872655417e-7 1.6592894066607455e-7 5594/7316/6714/8569/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 14 Murine_minute_virus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 42/2393 86/10654 6.318582797209407e-8 3.2565003647156175e-7 1.7139475603766406e-7 8454/1017/8945/5684/246184/7321/5707/991/8697/9212/6500/5705/10197/7316/891/5695/890/4085/983/6790/5714/51433/5701/6502/5708/5686/8900/51529/7324/64682/29945/10393/9232/6233/51434/701/51343/7311/9184/5347/7314/996 42 Murine_minute_virus R-HSA-453276 Regulation of mitotic cell cycle 42/2393 86/10654 6.318582797209407e-8 3.2565003647156175e-7 1.7139475603766406e-7 8454/1017/8945/5684/246184/7321/5707/991/8697/9212/6500/5705/10197/7316/891/5695/890/4085/983/6790/5714/51433/5701/6502/5708/5686/8900/51529/7324/64682/29945/10393/9232/6233/51434/701/51343/7311/9184/5347/7314/996 42 Murine_minute_virus R-HSA-203927 MicroRNA (miRNA) biogenesis 18/2393 24/10654 6.531728844361473e-8 3.3534546557258136e-7 1.7649761345925335e-7 27161/5434/5440/5430/5436/5441/5438/5431/5435/5433/5437/5439/192669/5901/29102/26523/5432/23405 18 Murine_minute_virus R-HSA-9612973 Autophagy 53/2393 119/10654 6.580704277062864e-8 3.3657037142229915e-7 1.7714230074857848e-7 137492/64422/7405/1459/25978/1915/51160/27243/79065/9140/8878/9821/7249/8897/58528/1080/1460/10533/10013/64419/91782/79720/9474/192111/7316/11152/8655/1457/51271/8678/6714/64223/8408/3320/6009/55054/81631/6233/3326/2475/9804/7311/23710/93343/55626/7251/7431/3312/30849/57521/140735/92421/7314 53 Murine_minute_virus R-HSA-2559585 Oncogene Induced Senescence 22/2393 33/10654 6.956745958631213e-8 3.5135326104405006e-7 1.8492276897055266e-7 1019/2077/7027/1029/57690/5594/7316/2114/1869/1871/4194/1031/1021/192669/7157/6233/1032/7311/26523/7314/5595/4193 22 Murine_minute_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 22/2393 33/10654 6.956745958631213e-8 3.5135326104405006e-7 1.8492276897055266e-7 1147/351/4790/6885/387522/23118/8517/7316/7335/5970/4792/4793/3656/10454/3654/7189/6233/7311/7334/3551/4791/7314 22 Murine_minute_virus R-HSA-68962 Activation of the pre-replicative complex 22/2393 33/10654 6.956745958631213e-8 3.5135326104405006e-7 1.8492276897055266e-7 1017/4172/6118/8318/8317/54107/4173/5422/84515/56655/5426/4171/51053/6119/10926/5427/990/81620/23649/6117/5001/4176 22 Murine_minute_virus R-HSA-73887 Death Receptor Signalling 60/2393 141/10654 6.974624435650545e-8 3.5135326104405006e-7 1.8492276897055266e-7 7124/1147/57142/8841/7186/56957/4790/6885/5584/7531/8737/7204/29/55072/8878/11214/23421/23118/841/27005/8517/4615/8887/6453/7316/50650/5970/4792/23263/8797/50649/9826/7128/7132/329/9138/9099/843/23365/10616/10454/3066/3065/8567/3654/7189/6233/7410/7311/26574/8772/331/5599/8717/1540/3551/7185/8795/7314/10672 60 Murine_minute_virus R-HSA-174414 Processive synthesis on the C-strand of the telomere 11/2393 11/10654 7.210684133796767e-8 3.6188452207069914e-7 1.9046553793194694e-7 6118/2237/1763/57804/3978/5425/5111/6119/6117/10714/5424 11 Murine_minute_virus R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 29/2393 51/10654 1.0484321550997794e-7 5.242160775498897e-7 2.759031987104682e-7 84617/2589/5321/1783/10382/347688/830/7277/10381/23299/1780/5048/1781/22930/8655/1639/832/25782/5870/636/2590/347733/10376/51143/10383/140735/7280/51164/1778 29 Murine_minute_virus R-HSA-1980143 Signaling by NOTCH1 37/2393 73/10654 1.1320631134634163e-7 5.639273502011069e-7 2.968038685268984e-7 8454/8841/79718/142678/892/113878/23220/6500/409/3091/10013/7316/9611/3714/8650/9759/9612/102/4609/10014/22938/1387/6907/2033/55294/3066/3065/7088/83737/92737/9794/6233/7311/57534/3516/4851/7314 37 Murine_minute_virus R-HSA-168638 NOD1/2 Signaling Pathway 23/2393 36/10654 1.142437077065942e-7 5.648950860768864e-7 2.973132031983612e-7 1147/6885/387522/23118/841/8517/7316/7335/7128/1432/329/3656/10454/83737/3654/7189/6233/7311/7334/1540/3551/6300/7314 23 Murine_minute_virus R-HSA-176033 Interactions of Vpr with host cellular proteins 23/2393 36/10654 1.142437077065942e-7 5.648950860768864e-7 2.973132031983612e-7 23165/4928/5903/9631/348995/79023/57122/23636/23511/293/292/23279/4927/79902/9883/23225/8086/3836/9972/8021/6396/55746/8480 23 Murine_minute_virus R-HSA-70326 Glucose metabolism 43/2393 91/10654 1.4668671357607533e-7 7.2264778011743e-7 3.803409369039105e-7 23165/4928/7167/5903/2597/9631/5315/5567/348995/79023/57122/23636/5214/83440/23511/5528/5230/10165/23279/4927/79902/5566/5519/9883/2023/5209/226/23225/4190/5208/5224/8086/5213/9972/5518/4191/8021/6396/55746/8480/5515/5223/5516 43 Murine_minute_virus R-HSA-5357786 TNFR1-induced proapoptotic signaling 12/2393 13/10654 1.6646786189689762e-7 8.170949997869701e-7 4.300499998878789e-7 7124/7186/56957/8737/841/27005/7128/7132/9099/8772/8717/1540 12 Murine_minute_virus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 18/2393 25/10654 1.841360948460965e-7 9.005195879334645e-7 4.7395767785971825e-7 1147/2308/5170/2309/207/4303/84335/1027/7249/64223/2932/3164/79109/2475/1385/2931/253260/4193 18 Murine_minute_virus R-HSA-5693606 DNA Double Strand Break Response 38/2393 77/10654 1.883520964576772e-7 9.177883972846817e-7 4.830465248866746e-7 8467/25/3838/322/10111/51588/51720/11200/472/7336/580/29086/7316/2140/2070/9031/9656/7341/10524/4683/165918/7157/9682/7329/8924/6233/672/2138/7158/7311/9025/79184/23030/5536/5599/7334/2139/7314 38 Murine_minute_virus R-HSA-199977 ER to Golgi Anterograde Transport 63/2393 154/10654 1.896099998515308e-7 9.205702891342438e-7 4.845106784917072e-7 9919/84364/22820/84617/6711/11014/10342/6712/55291/1783/51014/2801/10484/10382/10802/347688/830/7277/10381/1780/1604/9554/377/1781/9570/22872/8655/1315/11196/1639/832/55738/11316/22870/100302736/347733/10376/10972/51143/1314/9632/23243/9276/6709/5537/9871/27095/7109/10383/6396/84342/26286/1453/64689/26958/140735/7280/10427/54732/51164/1778/22818/372 63 Murine_minute_virus R-HSA-187037 Signaling by NTRK1 (TRKA) 39/2393 80/10654 1.9726173000616599e-7 9.542625206074456e-7 5.022434318986555e-7 1173/6464/5335/5899/5604/1849/5594/1785/160/5528/6774/4205/9261/6714/5605/10818/5519/5898/5598/1432/4914/2885/1398/5900/8660/1385/163/6196/5906/5518/1213/1211/3845/3265/6300/7529/5595/5515/5516 39 Murine_minute_virus R-HSA-73886 Chromosome Maintenance 49/2393 110/10654 2.0325061846443985e-7 9.796972256919043e-7 5.156301187852127e-7 8467/7014/6118/55839/79682/2237/55651/7015/1763/1058/401541/79019/57804/80152/4869/5982/79172/54107/7013/23421/64105/3978/5422/10856/5425/5111/56655/5426/55166/6119/5928/1736/2491/5427/5985/65057/1060/91687/5984/51773/23649/8607/5983/6117/5981/10714/64946/54386/5424 49 Murine_minute_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 27/2393 47/10654 2.1685675643099377e-7 1.0378144772054702e-6 5.462181458976158e-7 8454/8841/79718/892/6500/3091/10013/7316/9611/9759/9612/4609/10014/22938/1387/6907/2033/55294/3066/3065/7088/9794/6233/7311/3516/4851/7314 27 Murine_minute_virus R-HSA-73762 RNA Polymerase I Transcription Initiation 27/2393 47/10654 2.1685675643099377e-7 1.0378144772054702e-6 5.462181458976158e-7 5434/5440/902/9112/404672/5441/51082/5435/4331/7343/1108/2966/5928/5437/57459/2965/54815/2068/3066/3065/2071/1107/2968/57504/84172/2967/1022 27 Murine_minute_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 30/2393 55/10654 2.2260507454343236e-7 1.0615330956875424e-6 5.587016293092327e-7 1147/351/4790/6885/387522/23118/841/8517/7316/7335/5970/22861/7128/1432/329/10628/3656/10454/83737/3654/7189/6233/3326/7311/7334/1540/3551/6300/4791/7314 30 Murine_minute_virus R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 13/2393 15/10654 2.3807627575073699e-7 1.1193761737052196e-6 5.891453545816944e-7 6737/29110/81844/23220/147945/7316/51428/22954/3661/6233/7311/81030/7314 13 Murine_minute_virus R-HSA-69183 Processive synthesis on the lagging strand 13/2393 15/10654 2.3807627575073699e-7 1.1193761737052196e-6 5.891453545816944e-7 6118/2237/1763/57804/3978/5422/5425/5111/6119/23649/6117/10714/5424 13 Murine_minute_virus R-HSA-937039 IRAK1 recruits IKK complex 13/2393 15/10654 2.3807627575073699e-7 1.1193761737052196e-6 5.891453545816944e-7 1147/387522/8517/7316/7335/57162/3654/7189/6233/7311/7334/3551/7314 13 Murine_minute_virus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 13/2393 15/10654 2.3807627575073699e-7 1.1193761737052196e-6 5.891453545816944e-7 1147/387522/8517/7316/7335/57162/3654/7189/6233/7311/7334/3551/7314 13 Murine_minute_virus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 14/2393 17/10654 2.723465154212567e-7 1.2760291281974963e-6 6.715942779986822e-7 1147/4790/8737/8517/4615/7098/5970/4792/4793/1660/81030/3551/4791/148022 14 Murine_minute_virus R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 32/2393 61/10654 2.9294487503561533e-7 1.367756559399737e-6 7.198718733682827e-7 25/51517/5747/4690/4651/10093/4627/10458/5594/4644/147179/2209/6850/10552/10094/10152/10092/8936/4650/10163/3320/998/2885/1398/7410/10096/3326/10097/23191/10095/10109/5595 32 Murine_minute_virus R-HSA-174437 Removal of the Flap Intermediate from the C-strand 10/2393 10/10654 3.2207520738620606e-7 1.4985443676997088e-6 7.887075619472151e-7 6118/2237/1763/57804/5425/5111/6119/6117/10714/5424 10 Murine_minute_virus R-HSA-5693565 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 37/2393 76/10654 4.215965957218257e-7 1.954807744869365e-6 1.028846181510192e-6 8467/25/322/10111/51588/51720/11200/472/7336/580/29086/7316/2140/2070/9031/9656/7341/10524/4683/165918/7157/9682/7329/8924/6233/672/2138/7158/7311/9025/79184/23030/5536/5599/7334/2139/7314 37 Murine_minute_virus R-HSA-8852135 Protein ubiquitination 38/2393 79/10654 4.3626498416116924e-7 2.0158450992274716e-6 1.0609711048565639e-6 7321/79139/56852/65264/9646/79577/7336/7326/5591/7323/8239/7316/7317/56254/8915/5111/7415/7322/9810/54623/7347/8078/118424/7324/5830/6233/7327/7311/5192/27338/7334/7874/7332/3105/997/80349/7314/123169 38 Murine_minute_virus R-HSA-180910 Vpr-mediated nuclear import of PICs 21/2393 33/10654 4.533865617668319e-7 2.0848481346055365e-6 1.0972884918976507e-6 23165/4928/5903/9631/348995/79023/57122/23636/23511/23279/4927/79902/9883/23225/8086/3836/9972/8021/6396/55746/8480 21 Murine_minute_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 40/2393 85/10654 4.543101905259826e-7 2.0848481346055365e-6 1.0972884918976507e-6 8454/1017/1019/5684/994/902/7027/5707/207/1027/6500/5705/10197/4149/286826/91768/7316/1869/5753/993/5695/890/4331/5714/4609/5928/5701/6502/5708/5686/1874/595/8900/6233/55957/51343/7311/7465/1022/7314 40 Murine_minute_virus R-HSA-5617833 Cilium Assembly 76/2393 201/10654 5.058326516557085e-7 2.313364345456141e-6 1.2175601818190216e-6 115106/22995/84617/79738/55559/22981/7531/54903/80776/6608/11190/203068/3842/54801/7532/10575/1454/10382/347688/95681/121441/7277/79441/10013/10381/79989/9727/7203/5048/1781/23354/60412/8655/9738/79598/983/1639/89891/55722/4957/50807/5566/132320/84131/7840/7283/347733/3320/22919/10376/11336/1069/5577/80254/26005/54930/5518/10383/54820/5347/22948/9662/55142/23332/1453/9793/8481/57787/140735/93323/7280/9657/57576/1778/55770/23265 76 Murine_minute_virus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 17/2393 24/10654 5.969014265153191e-7 2.7113488526458566e-6 1.4270257119188716e-6 6885/5606/387522/23118/8517/7316/7335/9261/1432/3656/10454/3654/7189/6233/7311/7334/7314 17 Murine_minute_virus R-HSA-933542 TRAF6 mediated NF-kB activation 17/2393 24/10654 5.969014265153191e-7 2.7113488526458566e-6 1.4270257119188716e-6 1147/351/7186/4790/57506/4214/7706/8517/5970/4792/4793/23586/64135/7189/84282/3551/4791 17 Murine_minute_virus R-HSA-5621481 C-type lectin receptors (CLRs) 58/2393 142/10654 6.115658765169966e-7 2.7685752517999173e-6 1.4571448693683772e-6 8454/1147/5170/8945/5684/4773/4790/6885/387522/4772/7321/5707/5567/5336/9039/6500/23118/10892/3708/5705/841/10197/8517/56667/7316/94025/5695/7335/5970/4792/6850/10768/8915/5714/6714/5566/7322/5701/1387/4067/5708/5686/2033/5534/10454/5894/7189/6233/7311/5971/3710/3845/7334/3265/3551/997/4791/7314 58 Murine_minute_virus R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 20/2393 31/10654 6.191266286175095e-7 2.774681211864424e-6 1.4603585325602229e-6 23165/4928/5903/9631/348995/79023/57122/23636/23511/23279/4927/79902/9883/23225/8086/9972/8021/6396/55746/8480 20 Murine_minute_virus R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 20/2393 31/10654 6.191266286175095e-7 2.774681211864424e-6 1.4603585325602229e-6 1499/5525/139285/1856/5526/1452/4041/5528/23401/5519/2932/324/8312/5529/1855/5527/1857/5518/5515/5516 20 Murine_minute_virus R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 20/2393 31/10654 6.191266286175095e-7 2.774681211864424e-6 1.4603585325602229e-6 23165/4928/5903/9631/348995/79023/57122/23636/23511/23279/4927/79902/9883/23225/8086/9972/8021/6396/55746/8480 20 Murine_minute_virus R-HSA-6807878 COPI-mediated anterograde transport 45/2393 101/10654 6.283003505342323e-7 2.806408232386238e-6 1.4770569644138092e-6 84364/22820/84617/6711/11014/6712/1783/51014/2801/10382/347688/830/7277/10381/1780/1604/377/1781/9570/8655/1315/1639/832/55738/11316/100302736/347733/10376/10972/51143/1314/9276/6709/10383/84342/26286/64689/26958/140735/7280/54732/51164/1778/22818/372 45 Murine_minute_virus R-HSA-202424 Downstream TCR signaling 44/2393 98/10654 6.42623937035918e-7 2.860850749595117e-6 1.505710920839535e-6 8454/1147/3120/5170/8945/5684/4790/6885/387522/3117/7321/5707/3119/6500/3123/23118/10892/5705/10197/8517/3113/3115/7316/3122/5695/7335/5970/4792/50852/8915/5714/7322/5701/5708/5686/5728/7189/6233/7311/3127/7334/3551/997/7314 44 Murine_minute_virus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 38/2393 80/10654 6.525060236347496e-7 2.8952254028826637e-6 1.5238028436224544e-6 8454/1017/8945/5684/246184/7321/5707/991/8697/6500/5705/10197/7316/891/5695/890/4085/983/5714/51433/5701/5708/5686/8900/51529/7324/64682/29945/10393/6233/51434/701/51343/7311/9184/5347/7314/996 38 Murine_minute_virus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 40/2393 86/10654 6.667814321165312e-7 2.942532046320023e-6 1.548701077010538e-6 25/5335/51517/5747/4690/4651/10093/5336/4627/10458/5594/4644/147179/2209/3708/6850/10552/10768/10094/10152/6714/10092/8936/4650/10163/4067/3320/998/2885/1398/7410/10096/3326/10097/23191/3710/5338/10095/10109/5595 40 Murine_minute_virus R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 22/2393 36/10654 6.675595090158857e-7 2.942532046320023e-6 1.548701077010538e-6 25/51517/5747/4690/10093/10458/5594/147179/10552/10094/10152/10092/8936/10163/998/2885/10096/10097/23191/10095/10109/5595 22 Murine_minute_virus R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 15/2393 20/10654 8.661445681652757e-7 3.7929206579786585e-6 1.996274030515083e-6 246184/7321/991/8697/4085/51433/51529/7324/64682/29945/10393/51434/701/9184/996 15 Murine_minute_virus R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 15/2393 20/10654 8.661445681652757e-7 3.7929206579786585e-6 1.996274030515083e-6 246184/7321/991/8697/4085/51433/51529/7324/64682/29945/10393/51434/701/9184/996 15 Murine_minute_virus R-HSA-174411 Polymerase switching on the C-strand of the telomere 12/2393 14/10654 9.249681340769333e-7 3.998249353751905e-6 2.1043417651325815e-6 57804/5982/5422/5425/5111/5985/5984/23649/5983/5981/10714/5424 12 Murine_minute_virus R-HSA-69091 Polymerase switching 12/2393 14/10654 9.249681340769333e-7 3.998249353751905e-6 2.1043417651325815e-6 57804/5982/5422/5425/5111/5985/5984/23649/5983/5981/10714/5424 12 Murine_minute_virus R-HSA-69109 Leading Strand Synthesis 12/2393 14/10654 9.249681340769333e-7 3.998249353751905e-6 2.1043417651325815e-6 57804/5982/5422/5425/5111/5985/5984/23649/5983/5981/10714/5424 12 Murine_minute_virus R-HSA-69166 Removal of the Flap Intermediate 12/2393 14/10654 9.249681340769333e-7 3.998249353751905e-6 2.1043417651325815e-6 6118/2237/1763/57804/5422/5425/5111/6119/23649/6117/10714/5424 12 Murine_minute_virus R-HSA-156711 Polo-like kinase mediated events 13/2393 16/10654 1.0067056181112344e-6 4.323671564964917e-6 2.2756166131394296e-6 2305/1063/9133/286826/891/993/9088/5928/2033/995/55957/5347/7465 13 Murine_minute_virus R-HSA-193639 p75NTR signals via NF-kB 13/2393 16/10654 1.0067056181112344e-6 4.323671564964917e-6 2.2756166131394296e-6 4790/5584/8878/4615/7316/5970/4792/3654/7189/6233/7311/3551/7314 13 Murine_minute_virus R-HSA-8943724 Regulation of PTEN gene transcription 31/2393 61/10654 1.112998563723714e-6 4.7649139788810765e-6 2.507849462568987e-6 8841/5468/1822/23186/2146/9112/6045/5594/80012/58528/1108/64223/10014/5928/57459/54815/23512/6009/6615/3066/3065/7157/1107/23028/2475/57504/1386/648/57521/6015/5595 31 Murine_minute_virus R-HSA-109581 Apoptosis 68/2393 178/10654 1.2957179188794285e-6 5.529496851268899e-6 2.910261500667841e-6 23368/23643/4000/1828/3837/5684/7186/1499/7531/5747/7027/1029/5707/8737/7532/207/10971/5594/63967/7533/2810/118/5705/841/10197/7099/7534/7316/1869/5695/8655/7082/6774/5714/8797/8428/5701/329/999/100302736/929/5708/5686/708/324/5534/9414/7157/3836/6233/6709/7311/7161/8772/331/581/5599/353376/8717/7431/57099/637/8795/140735/7529/7314/5595/148022 68 Murine_minute_virus R-HSA-5673000 RAF activation 20/2393 32/10654 1.3024409393176776e-6 5.540542408525993e-6 2.9160749518557864e-6 5604/5525/5526/8844/5528/6714/5605/5519/5529/5894/5527/5518/4140/3845/3265/369/5245/7529/5515/5516 20 Murine_minute_virus R-HSA-2559583 Cellular Senescence 73/2393 195/10654 1.3103304023343044e-6 5.5550791272801694e-6 2.923725856463247e-6 1017/7014/1019/5601/2077/4790/5606/9448/246184/7290/7027/1029/7321/2146/10111/6045/8697/57690/5594/1027/80012/7013/1051/50488/472/7316/2114/1869/890/6774/5970/9261/1871/51433/4194/1031/5598/5928/1432/10524/4683/65057/23512/1021/192669/7157/8900/51529/7324/64682/29945/10393/5609/6233/51434/1032/51343/6196/7311/57634/5599/648/26523/3456/6416/54386/3569/7314/996/6015/5595/4193/23043 73 Murine_minute_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 150/2393 473/10654 1.3141493159312042e-6 5.5550791272801694e-6 2.923725856463247e-6 54106/5170/1173/2963/3643/5434/5440/8065/6464/23543/85440/5335/5899/1495/1499/5604/6461/5747/4690/5782/5567/5430/10048/10273/207/5436/3911/1849/10458/2060/5578/5594/1785/3315/5908/3178/23118/51741/3708/2064/5441/58513/1289/6778/160/5438/5431/5528/5435/4686/7316/1500/5433/5753/9611/3185/6774/4205/102/9261/4734/10768/10413/10152/6772/6714/2099/8651/5605/10818/64223/5566/8569/5802/2962/5519/5898/8936/5598/5795/1432/867/10163/5437/4670/4067/4914/3320/2335/64759/3728/5439/1111/998/2066/83737/6233/2885/1398/3187/79109/7410/5774/2475/5900/8660/23191/1385/3685/163/7073/6196/7311/5906/9846/5518/1213/1729/3710/1956/1211/29924/581/9564/3845/10076/6777/3265/6300/1020/5781/30849/5432/3480/22916/10254/10603/5725/11140/1291/7529/5829/7314/253260/161742/5595/2887/5515/25920/5516 150 Murine_minute_virus R-HSA-202403 TCR signaling 50/2393 119/10654 1.3336128621387176e-6 5.619626525993339e-6 2.957698171575441e-6 8454/1147/3120/5170/8945/55740/5684/5335/4790/6885/4690/387522/3117/7321/5707/3119/6500/3123/23118/10892/5705/10197/8517/3113/3115/7316/3122/5695/7335/5970/4792/50852/8915/5714/7322/5795/5701/5708/51466/5686/7408/5728/7189/6233/7311/3127/7334/3551/997/7314 50 Murine_minute_virus R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic 75/2393 202/10654 1.358559732945423e-6 5.70680263995883e-6 3.0035803368204367e-6 3831/84364/22820/84617/2589/5321/11014/1783/9265/51014/10382/347688/55275/830/7277/10381/55605/23299/1780/9554/377/5048/1781/9570/22930/8655/1315/22836/1639/832/25782/55738/3796/5870/9183/10112/11316/636/9341/1062/9342/4124/100302736/2590/347733/3482/10376/10972/51143/1314/11004/250/9276/10228/10749/3799/6293/10383/84643/10139/8675/2800/84342/26286/57589/81930/26958/140735/7280/54732/51164/1523/1778/22818/372 75 Murine_minute_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 40/2393 88/10654 1.394787121740649e-6 5.840671072288968e-6 3.074037406467878e-6 3303/5684/5707/3842/207/5578/3184/3315/26986/5705/10197/7534/8125/677/7538/7316/5695/9261/5714/8741/1432/5701/5708/5686/55802/1981/6233/7514/7311/8021/51010/54464/56915/3304/3312/8570/6418/7529/7314/1994 40 Murine_minute_virus R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 17/2393 25/10654 1.474027756312428e-6 6.153262284917924e-6 3.2385590973252225e-6 3135/3107/10484/10802/821/811/22872/567/3106/3309/9632/9871/3133/3134/6396/3105/10427 17 Murine_minute_virus R-HSA-429914 Deadenylation-dependent mRNA decay 29/2393 56/10654 1.49197590398487e-6 6.208843824036416e-6 3.2678125389665347e-6 1656/80153/23644/27257/4849/25804/4850/255967/26986/28960/219988/4848/23019/55802/1981/1973/10767/196513/1977/1975/55571/9775/51010/54464/56915/85456/29883/1974/80349 29 Murine_minute_virus R-HSA-166520 Signaling by NTRKs 44/2393 101/10654 1.7691098543308791e-6 7.339341191341727e-6 3.862811153337752e-6 1173/6464/5335/5899/5604/1849/5594/1785/160/5528/6774/4205/9261/6714/5605/10818/5802/5519/5898/5598/1432/4914/2885/1398/5900/8660/1385/163/6196/5906/5518/1213/1211/581/3845/3265/6300/1020/5781/7529/5595/5515/25920/5516 44 Murine_minute_virus R-HSA-69202 Cyclin E associated events during G1/S transition 38/2393 83/10654 2.0463786368655843e-6 8.46341781913544e-6 4.454430431123917e-6 8454/1017/1019/5684/902/7027/5707/207/1027/6500/5705/10197/4149/286826/91768/7316/1869/5753/993/5695/890/4331/5714/4609/5928/5701/6502/5708/5686/1874/595/8900/6233/55957/7311/7465/1022/7314 38 Murine_minute_virus R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 22/2393 38/10654 2.4299648696819873e-6 1.0018932078073423e-5 5.273122146354433e-6 6597/196528/1459/6045/80012/1460/6598/6599/28996/1457/6603/51412/8289/2033/84333/6605/861/57492/648/23429/55193/6015 22 Murine_minute_virus R-HSA-5357801 Programmed Cell Death 68/2393 181/10654 2.5896980972216335e-6 1.0644771319868065e-5 5.6025112209831916e-6 23368/23643/4000/1828/3837/5684/7186/1499/7531/5747/7027/1029/5707/8737/7532/207/10971/5594/63967/7533/2810/118/5705/841/10197/7099/7534/7316/1869/5695/8655/7082/6774/5714/8797/8428/5701/329/999/100302736/929/5708/5686/708/324/5534/9414/7157/3836/6233/6709/7311/7161/8772/331/581/5599/353376/8717/7431/57099/637/8795/140735/7529/7314/5595/148022 68 Murine_minute_virus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 10/2393 11/10654 2.821758867868581e-6 1.15631708958529e-5 6.085879418869947e-6 6885/23118/7098/7316/10454/7189/6233/7311/7314/148022 10 Murine_minute_virus R-HSA-176412 Phosphorylation of the APC/C 14/2393 19/10654 2.922316480857717e-6 1.1938731964479696e-5 6.28354313919984e-6 246184/7321/8697/891/983/51433/51529/7324/64682/29945/10393/51434/5347/996 14 Murine_minute_virus R-HSA-948021 Transport to the Golgi and subsequent modification 69/2393 185/10654 2.9551397496054587e-6 1.2036131502952324e-5 6.3348060541854325e-6 9919/84364/22820/84617/6711/11014/10342/6712/55291/1783/8703/51014/2801/10484/10382/10802/347688/830/7277/10381/4249/1780/1604/9554/377/1781/9570/22872/8655/1315/11196/1639/6484/832/55738/11316/4124/22870/100302736/347733/10376/10972/51143/1314/9632/23243/2683/9276/6709/5537/9871/27095/7109/10383/9334/6396/84342/26286/1453/64689/26958/140735/7280/10427/54732/51164/1778/22818/372 69 Murine_minute_virus R-HSA-180024 DARPP-32 events 17/2393 26/10654 3.3658445886201158e-6 1.3667368935608954e-5 7.193352071373134e-6 5575/5567/5142/5573/5528/5566/5519/5576/5534/5499/5577/5144/5518/1020/5141/5515/5516 17 Murine_minute_virus R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 13/2393 17/10654 3.3933727018536677e-6 1.3696142832782874e-5 7.208496227780461e-6 23643/7186/8737/841/7099/8797/100302736/929/8772/353376/8717/8795/148022 13 Murine_minute_virus R-HSA-432142 Platelet sensitization by LDL 13/2393 17/10654 3.3933727018536677e-6 1.3696142832782874e-5 7.208496227780461e-6 5321/5525/5526/5528/5519/1432/5529/5527/7804/5518/5781/5515/5516 13 Murine_minute_virus R-HSA-209560 NF-kB is activated and signals survival 11/2393 13/10654 3.5548815463081885e-6 1.4304928744903822e-5 7.528909865738854e-6 4790/8878/7316/5970/4792/3654/7189/6233/7311/3551/7314 11 Murine_minute_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 29/2393 58/10654 3.759389677560242e-6 1.4904089254232912e-5 7.844257502227848e-6 8454/8841/79718/142678/892/6500/10013/7316/9611/3714/9759/9612/102/4609/10014/22938/1387/6907/2033/55294/3066/3065/9794/6233/7311/57534/3516/4851/7314 29 Murine_minute_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 29/2393 58/10654 3.759389677560242e-6 1.4904089254232912e-5 7.844257502227848e-6 8454/8841/79718/142678/892/6500/10013/7316/9611/3714/9759/9612/102/4609/10014/22938/1387/6907/2033/55294/3066/3065/9794/6233/7311/57534/3516/4851/7314 29 Murine_minute_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 29/2393 58/10654 3.759389677560242e-6 1.4904089254232912e-5 7.844257502227848e-6 8454/8841/79718/142678/892/6500/10013/7316/9611/3714/9759/9612/102/4609/10014/22938/1387/6907/2033/55294/3066/3065/9794/6233/7311/57534/3516/4851/7314 29 Murine_minute_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 29/2393 58/10654 3.759389677560242e-6 1.4904089254232912e-5 7.844257502227848e-6 8454/8841/79718/142678/892/6500/10013/7316/9611/3714/9759/9612/102/4609/10014/22938/1387/6907/2033/55294/3066/3065/9794/6233/7311/57534/3516/4851/7314 29 Murine_minute_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 29/2393 58/10654 3.759389677560242e-6 1.4904089254232912e-5 7.844257502227848e-6 8454/8841/79718/142678/892/6500/10013/7316/9611/3714/9759/9612/102/4609/10014/22938/1387/6907/2033/55294/3066/3065/9794/6233/7311/57534/3516/4851/7314 29 Murine_minute_virus R-HSA-1852241 Organelle biogenesis and maintenance 100/2393 296/10654 4.083530985236938e-6 1.614139091509586e-5 8.49546890268203e-6 115106/22995/84617/79738/55559/8841/55735/79718/22981/7531/54903/80776/6608/11190/203068/3842/54801/7532/10575/1454/10382/347688/95681/121441/7277/200186/79441/10013/10381/3313/79989/4209/9727/7203/5048/1781/23354/9611/5469/60412/8655/9738/79598/54927/983/1639/89891/55722/4957/50807/5566/64784/132320/84131/1432/1387/7840/6907/7283/347733/3320/22919/2101/10376/11336/6648/1069/6256/5577/80254/1385/26005/54930/10499/5518/10383/1386/54820/5347/22948/6742/9662/55142/23332/1453/6300/9793/23373/133522/8481/57787/140735/93323/7280/9657/96764/57576/1778/55770/23265 100 Murine_minute_virus R-HSA-187687 Signalling to ERKs 20/2393 34/10654 4.9997429701775885e-6 1.964708381242806e-5 1.0340570427593716e-5 6464/5899/5604/5594/9261/6714/5605/10818/5898/1432/4914/2885/1398/5900/5906/3845/3265/6300/7529/5595 20 Murine_minute_virus R-HSA-4791275 Signaling by WNT in cancer 20/2393 34/10654 4.9997429701775885e-6 1.964708381242806e-5 1.0340570427593716e-5 1487/1499/5525/139285/5526/1452/4041/5528/8658/5519/2932/324/8312/5529/5527/1488/5518/80351/5515/5516 20 Murine_minute_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 27/2393 53/10654 5.13607741965428e-6 2.0123812112095715e-5 1.0591480058997744e-5 23368/7531/7027/1029/7532/207/10971/5594/7533/2810/841/7534/1869/8655/6774/708/5534/7157/7161/331/581/5599/57099/637/140735/7529/5595 27 Murine_minute_virus R-HSA-1632852 Macroautophagy 41/2393 95/10654 5.254238445964674e-6 2.0526762441961118e-5 1.0803559179979535e-5 64422/7405/1459/25978/27243/79065/9140/8878/9821/7249/8897/58528/1460/10533/64419/91782/9474/192111/7316/11152/8655/1457/8678/6714/64223/8408/6009/55054/81631/6233/2475/9804/7311/23710/55626/3312/30849/57521/140735/92421/7314 41 Murine_minute_virus R-HSA-449147 Signaling by Interleukins 144/2393 461/10654 5.395838088131984e-6 2.1018671622374588e-5 1.1062458748618203e-5 8454/7124/1147/2308/1052/8945/1326/9655/5684/5601/351/6464/4790/6627/6885/6597/5606/2309/90865/5604/4215/5782/387522/7412/5707/27250/27178/9180/3589/207/3911/5292/5451/9021/1849/29110/5594/8878/54472/6624/821/6500/5908/3091/23118/3383/5705/301/11009/10197/8517/6657/6778/4615/7534/3313/332/3662/5528/7316/6175/5695/79155/3185/6774/1435/7335/5970/4792/4205/6850/9261/59307/4793/3627/5714/6772/8651/8809/4609/5566/5519/5898/7132/4988/5598/1432/5701/867/4067/4088/3636/5708/3320/5686/200081/2335/3656/595/57162/3181/10454/998/7157/6648/5478/3654/7189/5609/6233/2885/1398/3716/8660/1385/6196/7311/6809/9846/4507/6888/5518/302/1386/7040/6935/5599/7431/6777/7334/3977/3312/3551/6773/6416/5781/3569/4791/5724/7314/3572/5595/5515/5516 144 Murine_minute_virus R-HSA-432722 Golgi Associated Vesicle Biogenesis 28/2393 56/10654 5.5127572089607265e-6 2.1411868579731518e-5 1.1269404515648166e-5 27131/164/26258/162/84062/9685/1176/5286/1174/9026/1785/8546/55330/8301/7037/9698/3482/9829/388552/10717/1213/2580/1211/8905/23431/3312/8907/4952 28 Murine_minute_virus R-HSA-8939211 ESR-mediated signaling 79/2393 223/10654 5.833025619545218e-6 2.2590330434076855e-5 1.1889647596882555e-5 5170/27161/2963/3838/5434/5440/6464/2309/9687/5747/59345/7031/8204/5430/207/5436/5451/57690/5594/1027/3315/10274/51523/5441/10735/5438/5431/5885/2100/5435/5433/1509/5469/1655/2289/6714/2099/4609/2962/10524/1387/5437/3320/2033/8243/9126/595/2783/8312/2782/5439/192669/3065/2066/861/23028/3326/7514/1385/1025/10499/23030/1386/1956/5536/3169/3845/904/3276/3265/26523/23189/8202/5432/3480/2773/10728/5595/7528 79 Murine_minute_virus R-HSA-4551638 SUMOylation of chromatin organization proteins 33/2393 71/10654 6.350301152984686e-6 2.4522776786742012e-5 1.2906724624601059e-5 23165/4928/5903/83746/9631/6045/80012/348995/79023/6613/57122/23636/23511/9759/23279/4927/79902/9883/7341/23225/23512/3066/3065/1107/8086/7329/9972/8021/6396/648/55746/8480/6015 33 Murine_minute_virus R-HSA-3247509 Chromatin modifying enzymes 93/2393 274/10654 7.099292229700393e-6 2.7258027472202084e-5 1.4346330248527412e-5 55904/55683/84678/23774/9070/10196/1810/1019/8841/5927/8464/23326/55167/11091/4790/9869/79718/84148/51742/6597/196528/23186/84193/8242/2146/1788/9112/10445/5929/284058/6598/6599/79960/7403/9611/2874/84289/10856/5970/11143/9612/29072/6603/51412/1108/9767/27097/5928/10524/1387/57459/64324/6907/8289/54815/23081/2033/23512/6605/595/6944/8473/3066/3065/9682/1107/79084/23028/23587/57492/23133/22992/57504/80854/58508/10499/23030/57634/1386/51317/55689/8607/6883/3276/51230/6187/51780/10362/10765/4791/55193/8089/54934 93 Murine_minute_virus R-HSA-4839726 Chromatin organization 93/2393 274/10654 7.099292229700393e-6 2.7258027472202084e-5 1.4346330248527412e-5 55904/55683/84678/23774/9070/10196/1810/1019/8841/5927/8464/23326/55167/11091/4790/9869/79718/84148/51742/6597/196528/23186/84193/8242/2146/1788/9112/10445/5929/284058/6598/6599/79960/7403/9611/2874/84289/10856/5970/11143/9612/29072/6603/51412/1108/9767/27097/5928/10524/1387/57459/64324/6907/8289/54815/23081/2033/23512/6605/595/6944/8473/3066/3065/9682/1107/79084/23028/23587/57492/23133/22992/57504/80854/58508/10499/23030/57634/1386/51317/55689/8607/6883/3276/51230/6187/51780/10362/10765/4791/55193/8089/54934 93 Murine_minute_virus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 19/2393 32/10654 7.146945895798187e-6 2.7362592858198775e-5 1.4401364662209881e-5 892/7027/7316/4092/4609/4089/22938/60436/8812/4088/1874/905/3065/6233/1025/7311/25937/904/7314 19 Murine_minute_virus R-HSA-1538133 G0 and Early G1 17/2393 27/10654 7.184936468609648e-6 2.741666823423343e-5 1.4429825386438647e-5 1017/7027/4149/286826/1869/993/890/983/5111/4609/5928/990/1874/3065/8900/55957/1859 17 Murine_minute_virus R-HSA-8878159 Transcriptional regulation by RUNX3 41/2393 96/10654 7.201990461529976e-6 2.741666823423343e-5 1.4429825386438647e-5 57154/5684/2309/1499/1029/5707/463/5705/10197/64750/7316/5695/9759/10413/5714/6714/4609/4089/22938/5701/1387/7005/4088/5708/5686/2033/7003/595/7157/861/9794/6233/7311/25937/7040/3845/3516/4851/3676/7314/4193 41 Murine_minute_virus R-HSA-6783310 Fanconi Anemia Pathway 22/2393 40/10654 7.70250245991352e-6 2.923896117927512e-5 1.5388926936460587e-5 6118/545/80198/2072/7316/197342/6119/84464/9937/2177/84126/7398/55215/57599/6233/2067/146956/7311/2189/6117/57697/7314 22 Murine_minute_virus R-HSA-69052 Switching of origins to a post-replicative state 39/2393 90/10654 7.87372132007489e-6 2.9804481833051846e-5 1.568656938581676e-5 8454/1017/4172/5684/246184/7321/5707/8697/6500/4173/5705/10197/7316/5695/890/84515/5714/4171/51433/5701/6502/5708/5686/990/81620/8900/51529/7324/64682/29945/10393/6233/51434/51343/7311/5001/4176/7314/996 39 Murine_minute_virus R-HSA-8848021 Signaling by PTK6 27/2393 54/10654 8.087225195680848e-6 3.0440679107338025e-5 1.6021410056493695e-5 1017/1019/207/9021/27043/1027/3091/116985/2064/10657/7316/5753/6774/867/6421/595/2066/6233/1398/7311/2034/1956/9564/3845/3265/5829/7314 27 Murine_minute_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 27/2393 54/10654 8.087225195680848e-6 3.0440679107338025e-5 1.6021410056493695e-5 1017/1019/207/9021/27043/1027/3091/116985/2064/10657/7316/5753/6774/867/6421/595/2066/6233/1398/7311/2034/1956/9564/3845/3265/5829/7314 27 Murine_minute_virus R-HSA-6784531 tRNA processing in the nucleus 28/2393 57/10654 8.52857213028045e-6 3.201200743578656e-5 1.6848424966203458e-5 23165/4928/5903/9631/348995/79023/57122/23636/23511/283742/1478/11260/23279/4927/79902/10898/9883/23225/5901/8086/1653/9972/8021/6396/80746/55746/51493/8480 28 Murine_minute_virus R-HSA-9020702 Interleukin-1 signaling 43/2393 103/10654 8.763788063796854e-6 3.280300560192119e-5 1.7264739790484835e-5 8454/1147/8945/1326/5684/351/4790/6885/5604/4215/387522/5707/8878/54472/6500/23118/5705/10197/8517/4615/7316/5695/79155/7335/5970/4792/4793/5714/5701/5708/5686/3656/57162/10454/3654/7189/6233/7311/7334/3551/6416/4791/7314 43 Murine_minute_virus R-HSA-199992 trans-Golgi Network Vesicle Budding 33/2393 72/10654 9.2179246083901855e-006 3.440673809259846e-5 1.810880952242024e-5 27131/164/351/8906/26258/162/84062/9685/1777/9179/1176/27243/5286/1174/9026/1785/8546/55330/8301/7037/9698/3482/9829/388552/10717/1213/2580/1211/8905/23431/3312/8907/4952 33 Murine_minute_virus R-HSA-5675482 Regulation of necroptotic cell death 13/2393 18/10654 9.69240573518715e-6 3.597735092839552e-5 1.8935447857050267e-5 7186/8737/841/7316/8797/329/6233/7311/8772/331/8717/8795/7314 13 Murine_minute_virus R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 13/2393 18/10654 9.69240573518715e-6 3.597735092839552e-5 1.8935447857050267e-5 7027/2810/891/983/6790/5111/1647/2033/995/1874/7157/581/3276 13 Murine_minute_virus R-HSA-114452 Activation of BH3-only proteins 18/2393 30/10654 1.0185805674541134e-5 3.7600494776543025e-5 1.978973409291738e-5 23368/7531/7027/7532/207/10971/7533/2810/7534/1869/8655/5534/7157/7161/5599/637/140735/7529 18 Murine_minute_virus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 18/2393 30/10654 1.0185805674541134e-5 3.7600494776543025e-5 1.978973409291738e-5 7321/65264/7326/8239/7316/7317/7322/7347/8078/7324/6233/7327/7311/27338/7874/7332/997/7314 18 Murine_minute_virus R-HSA-2562578 TRIF-mediated programmed cell death 9/2393 10/10654 1.1482575577425846e-5 4.2155208969179816e-5 2.2186952089042006e-5 23643/8737/841/7099/100302736/929/8772/353376/148022 9 Murine_minute_virus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 9/2393 10/10654 1.1482575577425846e-5 4.2155208969179816e-5 2.2186952089042006e-5 6885/23118/7316/3656/10454/7189/6233/7311/7314 9 Murine_minute_virus R-HSA-1834941 STING mediated induction of host immune responses 12/2393 16/10654 1.1670025415193098e-5 4.2726322558357246e-5 2.2487538188609075e-5 6737/29110/7520/23220/147945/6778/5591/51428/3428/3661/197358/2547 12 Murine_minute_virus R-HSA-69002 DNA Replication Pre-Initiation 37/2393 85/10654 1.179091325535423e-5 4.3051290905108086e-5 2.2658574160583202e-5 1017/4172/6118/5684/8318/5707/8317/54107/4173/5705/10197/7316/5422/1869/5695/84515/5714/56655/5426/4171/1871/51053/6119/5701/10926/5427/5708/5686/990/81620/6233/7311/23649/6117/5001/4176/7314 37 Murine_minute_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 36/2393 82/10654 1.2229361999441085e-5 4.441014926626302e-5 2.337376277171738e-5 8454/8945/5684/1487/1499/5525/139285/5707/5526/1452/6500/5705/10197/5528/7316/5695/23401/5714/5519/2932/5701/5708/5686/324/8312/5529/3065/7088/6233/5527/1488/7311/5518/7314/5515/5516 36 Murine_minute_virus R-HSA-2871837 FCERI mediated NF-kB activation 36/2393 82/10654 1.2229361999441085e-5 4.441014926626302e-5 2.337376277171738e-5 8454/1147/5170/8945/5684/4790/6885/387522/7321/5707/6500/23118/10892/5705/10197/8517/7316/5695/7335/5970/4792/8915/5714/7322/5701/4067/5708/5686/10454/7189/6233/7311/7334/3551/997/7314 36 Murine_minute_virus R-HSA-5689880 Ub-specific processing proteases 77/2393 220/10654 1.2575460264166673e-5 4.5543558794549573e-5 2.3970294102394506e-5 23358/10600/5684/23326/7186/6885/90865/5707/991/8737/8237/9817/4303/91833/63967/409/4086/1080/3091/5705/55031/27005/10197/8517/64750/8239/7316/993/5695/890/4792/9738/8658/11047/5714/4092/8678/9100/4609/79589/4194/23586/4089/81847/27430/5701/9097/329/7046/6502/9099/4088/8078/5708/5686/64135/5728/8312/10454/7157/8900/10869/9958/63891/7189/57599/6233/9804/7311/8607/1540/9736/80351/7874/10254/7314/4193 77 Murine_minute_virus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 34/2393 76/10654 1.2961141220024198e-5 4.6813825430815164e-5 2.4638855489902717e-5 5684/246184/7321/5707/991/8697/5705/10197/7316/891/5695/890/4085/983/5714/51433/5701/5708/5686/8900/51529/7324/64682/29945/10393/9232/6233/51434/701/7311/9184/5347/7314/996 34 Murine_minute_virus R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 11/2393 14/10654 1.3197897391156228e-5 4.7540813183197166e-5 2.5021480622735346e-5 5862/2801/5594/9133/891/26003/983/8548/5347/64689/5595 11 Murine_minute_virus R-HSA-3371511 HSF1 activation 10/2393 12/10654 1.3491741832795256e-5 4.846899210709288e-5 2.5509995845838354e-5 6118/7531/1915/10013/7415/6119/3320/3326/6117/10728 10 Murine_minute_virus R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 28/2393 59/10654 1.944911466786816e-5 6.968399372979502e-5 3.667578617357632e-5 7321/79139/56852/9646/79577/7336/5591/7323/7316/56254/8915/5111/7415/7322/9810/54623/118424/7324/5830/6233/7311/5192/7334/7332/3105/80349/7314/123169 28 Murine_minute_virus R-HSA-9018519 Estrogen-dependent gene expression 56/2393 150/10654 2.384953291079146e-5 8.522233093456147e-5 4.48538583866113e-5 27161/2963/3838/5434/5440/9687/7031/8204/5430/5436/5451/57690/10274/51523/5441/10735/5438/5431/5885/5435/5433/1509/5469/1655/2099/4609/2962/10524/1387/5437/3320/2033/8243/9126/595/8312/5439/192669/3065/2066/861/23028/3326/1025/10499/23030/1386/3169/904/3276/26523/23189/8202/5432/10728/7528 56 Murine_minute_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 13/2393 19/10654 2.436093245290093e-5 8.63588610764213e-5 4.545203214548489e-5 6464/5335/7316/867/3320/6233/2885/7311/1956/3845/3265/11140/7314 13 Murine_minute_virus R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 13/2393 19/10654 2.436093245290093e-5 8.63588610764213e-5 4.545203214548489e-5 246184/7321/991/8697/51433/51529/7324/64682/29945/10393/51434/51343/996 13 Murine_minute_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 13/2393 19/10654 2.436093245290093e-5 8.63588610764213e-5 4.545203214548489e-5 6464/5335/7316/867/3320/6233/2885/7311/1956/3845/3265/11140/7314 13 Murine_minute_virus R-HSA-446652 Interleukin-1 family signaling 53/2393 140/10654 2.4975798142631987e-5 8.830493274703658e-5 4.6476280393177135e-5 8454/1147/8945/1326/5684/351/4790/6885/90865/5604/4215/5782/387522/5707/27178/29110/8878/54472/6500/23118/5705/10197/8517/4615/7316/5695/79155/6774/7335/5970/4792/59307/4793/5714/8809/5701/4088/5708/5686/3656/57162/10454/3654/7189/6233/7311/5599/7334/3551/6416/5781/4791/7314 53 Murine_minute_virus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 33/2393 75/10654 2.6371226742610604e-5 9.299327325025845e-5 4.894382802645181e-5 5684/246184/7321/5707/991/8697/5705/10197/7316/891/5695/890/4085/983/5714/51433/5701/5708/5686/8900/51529/7324/64682/29945/10393/9232/6233/51434/701/7311/9184/7314/996 33 Murine_minute_virus R-HSA-162588 Budding and maturation of HIV virion 17/2393 29/10654 2.7648427784350237e-5 9.724118958275412e-5 5.1179573464607424e-5 137492/25978/51160/27243/91782/79720/7316/51271/23327/27183/5478/6233/7311/93343/7251/92421/7314 17 Murine_minute_virus R-HSA-1226099 Signaling by FGFR in disease 29/2393 63/10654 2.867262771244008e-5 1.0048603974196113e-4 5.2887389337874274e-5 2963/5434/5440/11052/5335/5430/5436/613/5441/5438/5431/5435/4686/5433/6774/6772/10818/2962/5437/5439/2885/9846/3845/6777/3265/5432/22916/7750/1523 29 Murine_minute_virus R-HSA-3371571 HSF1-dependent transactivation 15/2393 24/10654 2.8721009866545604e-5 1.0048603974196113e-4 5.2887389337874274e-5 3303/84335/3305/64223/26353/1387/3320/2033/3326/2475/3306/3304/3312/57521/10728 15 Murine_minute_virus R-HSA-73863 RNA Polymerase I Transcription Termination 18/2393 32/10654 3.4692932684970264e-5 1.2106387968192748e-4 6.371783141154078e-5 5434/5440/902/404672/5441/51082/5435/4331/7343/2966/5437/2965/2068/2071/2968/84172/2967/1022 18 Murine_minute_virus R-HSA-388841 Costimulation by the CD28 family 31/2393 70/10654 3.9370404964060276e-5 1.3702946143335265e-4 7.212076917544875e-5 3120/5170/1326/5525/3117/3119/5526/207/3123/3113/3115/5528/3122/6714/64223/5519/29126/4067/29851/5529/998/5527/2885/79109/2475/5518/3127/5781/253260/5515/5516 31 Murine_minute_virus R-HSA-8953750 Transcriptional Regulation by E2F6 19/2393 35/10654 4.118718928969441e-5 1.4298143432173705e-4 7.525338648512478e-5 5888/83746/7027/2146/8317/6045/84108/80012/4149/1869/5928/23512/1111/672/5932/648/23429/6015/6241 19 Murine_minute_virus R-HSA-8856828 Clathrin-mediated endocytosis 54/2393 146/10654 4.462538292621191e-5 1.5451682977034615e-4 8.13246472475506e-5 5869/9318/1173/23048/10093/1856/5286/2060/1601/9026/1785/409/1080/29763/112574/58513/160/6453/7316/10552/26130/3267/10094/55738/22848/8301/10092/7037/867/9341/3482/9829/10987/115548/29979/6233/2885/10096/10097/163/7311/1213/2580/1956/1211/29924/274/3312/10109/10254/3092/7314/4952/11252 54 Murine_minute_virus R-HSA-209543 p75NTR recruits signalling complexes 10/2393 13/10654 4.661460945441857e-5 1.6016301709979714e-4 8.429632478936692e-5 5584/8878/4615/7316/3654/7189/6233/7311/3551/7314 10 Murine_minute_virus R-HSA-3270619 IRF3-mediated induction of type I IFN 10/2393 13/10654 4.661460945441857e-5 1.6016301709979714e-4 8.429632478936692e-5 29110/7520/23220/147945/5591/51428/3428/3661/197358/2547 10 Murine_minute_virus R-HSA-68884 Mitotic Telophase/Cytokinesis 10/2393 13/10654 4.661460945441857e-5 1.6016301709979714e-4 8.429632478936692e-5 10274/23244/10735/25836/23047/5885/10112/8243/9126/5347 10 Murine_minute_virus R-HSA-2468052 Establishment of Sister Chromatid Cohesion 9/2393 11/10654 5.04562507704332e-5 1.71168040588305e-4 9.008844241489738e-5 10274/23244/10735/23047/5885/8243/9126/114799/113130 9 Murine_minute_virus R-HSA-2514853 Condensation of Prometaphase Chromosomes 9/2393 11/10654 5.04562507704332e-5 1.71168040588305e-4 9.008844241489738e-5 1459/1460/9133/10051/891/1457/983/23397/9918 9 Murine_minute_virus R-HSA-8934903 Receptor Mediated Mitophagy 9/2393 11/10654 5.04562507704332e-5 1.71168040588305e-4 9.008844241489738e-5 1459/9140/1460/9474/192111/1457/6714/8408/81631 9 Murine_minute_virus R-HSA-9614399 Regulation of localization of FOXO transcription factors 9/2393 11/10654 5.04562507704332e-5 1.71168040588305e-4 9.008844241489738e-5 2308/2309/7532/207/10971/4303/2810/7534/7529 9 Murine_minute_virus R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 9/2393 11/10654 5.04562507704332e-5 1.71168040588305e-4 9.008844241489738e-5 6885/23118/7316/80216/10454/7189/6233/7311/7314 9 Murine_minute_virus R-HSA-5213460 RIPK1-mediated regulated necrosis 13/2393 20/10654 5.526542668407568e-5 1.865382160117416e-4 9.81780084272324e-5 7186/8737/841/7316/8797/329/6233/7311/8772/331/8717/8795/7314 13 Murine_minute_virus R-HSA-5218859 Regulated Necrosis 13/2393 20/10654 5.526542668407568e-5 1.865382160117416e-4 9.81780084272324e-5 7186/8737/841/7316/8797/329/6233/7311/8772/331/8717/8795/7314 13 Murine_minute_virus R-HSA-429947 Deadenylation of mRNA 15/2393 25/10654 5.690230269285549e-5 1.915806171065989e-4 1.008319037403152e-4 4849/4850/255967/26986/4848/23019/1981/1973/1977/1975/55571/9775/85456/29883/1974 15 Murine_minute_virus R-HSA-69205 G1/S-Specific Transcription 16/2393 28/10654 7.340570105817068e-5 2.4652541207505945e-4 1.2975021688161023e-4 8318/7027/286826/5422/1869/983/5111/5928/990/1874/81620/3065/8900/55957/1719/6241 16 Murine_minute_virus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 31/2393 72/10654 7.602325323602904e-5 2.5404279136229157e-4 1.3370673229594292e-4 5684/246184/7321/5707/991/8697/9212/5705/10197/7316/5695/6790/5714/51433/5701/6502/5708/5686/51529/7324/64682/29945/10393/9232/6233/51434/51343/7311/5347/7314/996 31 Murine_minute_virus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 31/2393 72/10654 7.602325323602904e-5 2.5404279136229157e-4 1.3370673229594292e-4 5684/246184/7321/5707/991/8697/5705/10197/7316/5695/890/4085/983/5714/51433/5701/5708/5686/8900/51529/7324/64682/29945/10393/6233/51434/701/7311/9184/7314/996 31 Murine_minute_virus R-HSA-166208 mTORC1-mediated signalling 14/2393 23/10654 8.118828301066672e-5 2.7062761003555577e-4 1.4243558422923988e-4 6194/84335/58528/6198/29904/64223/1981/6009/1977/1975/2475/1978/57521/7529 14 Murine_minute_virus R-HSA-3899300 SUMOylation of transcription cofactors 22/2393 45/10654 8.552684168567448e-5 2.8438205424020794e-4 1.4967476538958312e-4 1487/8204/6045/51588/4869/80012/6613/28996/1655/9612/7341/1387/10521/1616/2033/7329/10155/10499/25942/7690/648/6015 22 Murine_minute_virus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 17/2393 31/10654 8.84741242215005e-5 2.934537783584422e-4 1.5444935703075904e-4 5601/1849/5594/5528/4205/9261/5519/5598/1432/1385/6196/5518/1386/5599/5595/5515/5516 17 Murine_minute_virus R-HSA-175474 Assembly Of The HIV Virion 11/2393 16/10654 1.0038239978749022e-4 3.3212942151910344e-4 1.7480495869426495e-4 137492/51160/79720/7316/51271/5478/6233/7311/93343/7251/7314 11 Murine_minute_virus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 31/2393 73/10654 1.0401973477538979e-4 3.4331636600744416e-4 1.806928242144443e-4 5684/246184/7321/5707/991/8697/5705/10197/7316/5695/890/4085/983/5714/51433/5701/5708/5686/8900/51529/7324/64682/29945/10393/6233/51434/701/7311/9184/7314/996 31 Murine_minute_virus R-HSA-4420097 VEGFA-VEGFR2 Pathway 39/2393 99/10654 1.0535055713119972e-4 3.4685441414203345e-4 1.8255495481159657e-4 5170/5335/1495/1499/6461/5747/4690/5567/207/10458/5578/3315/3708/1500/9261/10768/10152/6714/64223/5566/8936/1432/10163/3320/3728/998/1398/79109/7410/2475/23191/3685/3710/9564/3845/3265/6300/5829/253260 39 Murine_minute_virus R-HSA-389513 CTLA4 inhibitory signaling 13/2393 21/10654 1.1523479272322303e-4 3.775418636897772e-4 1.9870624404725115e-4 5525/5526/207/5528/6714/5519/4067/5529/5527/5518/5781/5515/5516 13 Murine_minute_virus R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 13/2393 21/10654 1.1523479272322303e-4 3.775418636897772e-4 1.9870624404725115e-4 4849/4869/4850/10769/4848/23019/995/7157/55571/5325/85456/29883/1263 13 Murine_minute_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 34/2393 83/10654 1.1664312761750379e-4 3.81223880505988e-4 2.0064414763473054e-4 8454/1147/8945/5684/4773/4790/6885/5966/4772/5707/6500/10892/5705/10197/8517/7316/5695/5970/4792/4793/8915/5714/5701/5708/5686/5534/5478/6233/7311/4794/3845/3265/3551/7314 34 Murine_minute_virus R-HSA-71291 Metabolism of amino acids and derivatives 114/2393 372/10654 1.234979133870281e-4 4.0264526505746386e-4 2.1191856055655992e-4 6158/440/4967/6138/6144/6203/5684/4736/1728/6206/6194/256987/6191/6166/6128/6132/6147/6129/5160/6217/5707/4143/6222/6176/383/57494/6152/6136/6125/54498/1737/57407/6224/6146/6154/6141/6202/4552/5705/4947/10197/6232/6134/6169/6160/6164/6155/6175/6218/5695/79048/10165/5723/6209/5714/6193/8140/6210/6229/6231/11224/6205/23446/6165/84245/6130/6142/6167/6204/5701/6228/2752/51540/23521/4946/5708/5686/445/6156/6235/6143/6181/6124/26227/64087/6207/3034/6139/6520/6233/587/51091/7311/6223/25873/4507/3921/6188/6189/8424/6135/6201/1734/6161/9045/6187/6168/6208/6157/6137/6122/6133/7296/6230 114 Murine_minute_virus R-HSA-5655253 Signaling by FGFR2 in disease 21/2393 43/10654 1.258672829147162e-4 4.093741725866983e-4 2.1546009083510439e-4 2963/5434/5440/5335/5430/5436/5441/5438/5431/5435/4686/5433/10818/2962/5437/5439/2885/3845/3265/5432/22916 21 Murine_minute_virus R-HSA-933541 TRAF6 mediated IRF7 activation 16/2393 29/10654 1.2972234508748837e-4 4.192537550020448e-4 2.2065987105370776e-4 3665/7186/80143/29110/57506/7706/23586/1387/2033/64135/3661/7189/10010/84282/9641/3456 16 Murine_minute_virus R-HSA-174490 Membrane binding and targetting of GAG proteins 10/2393 14/10654 1.301563896125751e-4 4.192537550020448e-4 2.2065987105370776e-4 137492/51160/79720/7316/51271/6233/7311/93343/7251/7314 10 Murine_minute_virus R-HSA-174495 Synthesis And Processing Of GAG, GAGPOL Polyproteins 10/2393 14/10654 1.301563896125751e-4 4.192537550020448e-4 2.2065987105370776e-4 137492/51160/79720/7316/51271/6233/7311/93343/7251/7314 10 Murine_minute_virus R-HSA-3371568 Attenuation phase 10/2393 14/10654 1.301563896125751e-4 4.192537550020448e-4 2.2065987105370776e-4 3303/3305/1387/3320/2033/3326/3306/3304/3312/10728 10 Murine_minute_virus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 32/2393 77/10654 1.3271535414836536e-4 4.264714018196872e-4 2.244586325366775e-4 84617/5684/51512/5707/63943/10382/347688/7277/9133/10381/5705/10197/7316/891/5695/983/5714/5701/347733/5708/3320/22919/5686/10376/7157/6233/3326/7311/10383/5347/7280/7314 32 Murine_minute_virus R-HSA-9634600 Regulation of glycolysis by fructose 2,6-bisphosphate metabolism 9/2393 12/10654 1.6134977758334778e-4 5.172456984729331e-4 2.72234578143649e-4 5567/5528/5566/5519/5209/5208/5518/5515/5516 9 Murine_minute_virus R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 12/2393 19/10654 1.6239927606841745e-4 5.193676132020988e-4 2.7335137536952563e-4 7027/4149/286826/1869/993/5111/4609/5928/990/1874/3065/55957 12 Murine_minute_virus R-HSA-9615710 Microautophagy 18/2393 35/10654 1.6526463242468715e-4 5.272728748787638e-4 2.775120394098756e-4 137492/25978/51160/27243/1080/10013/91782/79720/7316/51271/6233/7311/93343/7251/7431/3312/92421/7314 18 Murine_minute_virus R-HSA-2470946 Cohesin Loading onto Chromatin 8/2393 10/10654 1.854179209670997e-4 5.887678059144873e-4 3.0987779258657223e-4 10274/23244/10735/25836/23047/5885/8243/9126 8 Murine_minute_virus R-HSA-5685939 HDR through MMEJ (alt-NHEJ) 8/2393 10/10654 1.854179209670997e-4 5.887678059144873e-4 3.0987779258657223e-4 2237/10111/7515/4683/142/5932/10038/3980 8 Murine_minute_virus R-HSA-437239 Recycling pathway of L1 22/2393 47/10654 1.9212740176767382e-4 6.086305398786831e-4 3.203318630940437e-4 1173/84617/7430/10382/5594/347688/1785/7277/10381/160/8650/6714/347733/10376/5962/163/6196/3897/1213/10383/1211/7280 22 Murine_minute_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 42/2393 112/10654 2.1296033719573238e-4 6.730350279299089e-4 3.542289620683731e-4 8454/1147/8945/5684/4773/4790/6885/5966/4690/4772/5707/5336/6500/10892/3708/5705/10197/8517/7316/5695/5970/4792/6850/10768/4793/8915/5714/5701/4067/5708/5686/5534/5478/6233/2885/7311/3710/4794/3845/3265/3551/7314 42 Murine_minute_virus R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 13/2393 22/10654 2.238429072549506e-4 7.04106797468624e-4 3.705825249834863e-4 4000/351/994/2309/7531/2801/7001/993/824/995/6648/5052/1020 13 Murine_minute_virus R-HSA-8863678 Neurodegenerative Diseases 13/2393 22/10654 2.238429072549506e-4 7.04106797468624e-4 3.705825249834863e-4 4000/351/994/2309/7531/2801/7001/993/824/995/6648/5052/1020 13 Murine_minute_virus R-HSA-8951664 Neddylation 76/2393 234/10654 2.368154740287792e-4 7.43167998123101e-4 3.9114105164373737e-4 8454/9318/8945/56995/9655/5684/79754/8065/11091/23363/23038/25879/7321/5707/9021/26235/9817/9039/154881/5929/6500/3091/28952/5705/26259/55827/10197/53339/332/26263/7323/10517/7316/50717/5695/5714/27252/26118/7322/10489/5701/23369/1161/6502/7347/90864/55832/5708/1642/5686/55294/79269/10238/10987/7428/80176/23142/10116/6233/25793/7311/83987/2034/54461/80204/26232/8883/51667/54939/8816/26268/150684/9820/7314/8451/899 76 Murine_minute_virus R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic 38/2393 99/10654 2.4171235083522612e-4 7.567629675682313e-4 3.982962987201217e-4 3831/84364/22820/84617/11014/51014/10382/347688/7277/10381/55605/9554/377/1315/55738/3796/9183/10112/11316/1062/100302736/347733/10376/10972/1314/11004/9276/10749/3799/10383/84643/26286/81930/26958/7280/54732/22818/372 38 Murine_minute_virus R-HSA-9022692 Regulation of MECP2 expression and activity 17/2393 33/10654 2.440618657922345e-4 7.623377626144387e-4 4.0123040137602034e-4 27161/8841/79718/9212/57690/9611/28996/2874/9612/5566/6907/192669/3066/3065/1385/25942/26523 17 Murine_minute_virus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 18/2393 36/10654 2.615914467391141e-4 8.151919503032859e-4 4.290483948964662e-4 5604/8844/5594/409/5908/7414/6714/5605/2335/5894/8826/5906/4140/3845/3265/369/7529/5595 18 Murine_minute_virus R-HSA-5610787 Hedgehog 'off' state 42/2393 113/10654 2.6641947854583626e-4 8.283111397944794e-4 4.359532314707785e-4 8454/8945/84617/5684/2735/5575/54903/6608/5707/5567/1452/10382/6500/112/7277/10381/5705/10197/5573/7316/5695/2778/5727/8650/5714/5566/2932/5701/5576/347733/5708/5686/10376/83737/5577/6233/7311/10383/23432/8481/7280/7314 42 Murine_minute_virus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 14/2393 25/10654 2.790390361464479e-4 8.655377510098152e-4 4.5554618474200797e-4 1849/5594/5528/4205/9261/5519/5598/1432/1385/6196/5518/5595/5515/5516 14 Murine_minute_virus R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 20/2393 42/10654 2.797943599370866e-4 8.658763101979122e-4 4.5572437378837483e-4 9070/8945/1487/1499/207/5929/6657/7534/7316/9580/607/324/3065/7088/6233/7514/7311/331/25776/7314 20 Murine_minute_virus R-HSA-1236974 ER-Phagosome pathway 33/2393 83/10654 2.848400940857466e-4 8.794601983292637e-4 4.628737885943493e-4 23643/1147/3135/5684/3107/5707/811/5705/10333/10197/7099/8517/4615/9554/7316/5695/7096/567/5714/3106/5701/9341/929/5708/5686/6233/7311/3133/3134/7097/3551/3105/7314 33 Murine_minute_virus R-HSA-9006931 Signaling by Nuclear Receptors 93/2393 299/10654 2.8773630907843756e-4 8.863601245174857e-4 4.6650532869341356e-4 5170/27161/2963/3838/5434/5440/6464/8841/1374/79718/2309/9687/5747/59345/7031/5160/8204/5430/207/5436/5451/57690/5594/1027/3315/10274/51523/1737/5441/10735/6720/5438/5431/5885/2100/5435/5433/1509/9611/5469/2874/1655/9612/2289/6714/2099/4609/2962/10524/1387/5437/5467/6907/3320/2033/8243/9126/595/2783/8312/2782/5439/192669/3065/9682/2066/861/23028/6256/3326/7514/1385/1025/10499/23030/1386/1956/5914/5536/3169/3845/904/3276/3265/26523/23189/8202/5432/3480/2773/10728/5595/7528 93 Murine_minute_virus R-HSA-1169091 Activation of NF-kappaB in B cells 28/2393 67/10654 3.0590006487783147e-4 9.380001989388882e-4 4.936843152309937e-4 8454/1147/8945/5684/4790/6885/5966/5707/6500/10892/5705/10197/8517/7316/5695/5970/4792/4793/8915/5714/5701/5708/5686/6233/7311/4794/3551/7314 28 Murine_minute_virus R-HSA-6802952 Signaling by BRAF and RAF fusions 28/2393 67/10654 3.0590006487783147e-4 9.380001989388882e-4 4.936843152309937e-4 4000/27044/22906/5604/55750/8844/5594/409/5908/7414/10533/23164/8546/57085/6714/5605/2335/5894/56829/8826/5906/4140/3845/3265/369/7529/57670/5595 28 Murine_minute_virus R-HSA-111447 Activation of BAD and translocation to mitochondria 10/2393 15/10654 3.1168388402465376e-4 9.535534351439179e-4 5.018702290231147e-4 7531/7532/207/10971/7533/2810/7534/5534/637/7529 10 Murine_minute_virus R-HSA-167044 Signalling to RAS 12/2393 20/10654 3.231000501449304e-4 9.817552544086321e-4 5.167132917940169e-4 6464/5899/9261/6714/5898/1432/4914/2885/5900/3845/3265/6300 12 Murine_minute_virus R-HSA-2028269 Signaling by Hippo 12/2393 20/10654 3.231000501449304e-4 9.817552544086321e-4 5.167132917940169e-4 23286/7531/1856/7082/10413/6789/26524/9414/51421/25937/6788/7529 12 Murine_minute_virus R-HSA-8876384 Listeria monocytogenes entry into host cells 12/2393 20/10654 3.231000501449304e-4 9.817552544086321e-4 5.167132917940169e-4 1499/2060/7316/1500/6714/867/999/6233/2885/7311/10254/7314 12 Murine_minute_virus R-HSA-350054 Notch-HLH transcription pathway 15/2393 28/10654 3.2505442244401236e-4 9.854591087669153e-4 5.186626888246923e-4 8841/79718/10013/9611/9759/9612/10014/22938/1387/6907/3066/3065/9794/3516/4851 15 Murine_minute_virus R-HSA-8878166 Transcriptional regulation by RUNX2 44/2393 121/10654 3.3797239383046896e-4 0.0010223092725346013 5.380575118603165e-4 8454/57154/8493/25/1019/5684/8841/5707/10273/207/5594/6500/4086/59269/10013/5705/10197/7316/891/5695/9759/983/10413/5714/6772/6714/2099/4089/2932/5701/6502/5708/5686/2101/595/55294/861/6233/7311/25937/581/133522/7314/5595 44 Murine_minute_virus R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 33/2393 84/10654 3.6937613446468915e-4 0.001114783829240278 5.867283311790937e-4 7124/1052/1019/8841/4790/79718/9441/5468/29079/892/168544/1051/6720/688/9611/5469/5970/9612/9968/1387/6907/23389/2033/9967/7026/6256/9477/55588/10499/7040/9969/8202/96764 33 Murine_minute_virus R-HSA-6802957 Oncogenic MAPK signaling 29/2393 71/10654 3.8301896418053446e-4 0.0011533604764088004 6.070318296888423e-4 4000/27044/22906/5604/55750/8844/5594/409/5908/7414/10533/23164/8546/57085/6714/5605/2335/5894/56829/8826/5906/4140/3845/3265/369/5245/7529/57670/5595 29 Murine_minute_virus R-HSA-177929 Signaling by EGFR 22/2393 49/10654 4.016452236739864e-4 0.00120673677067969 6.351246161472053e-4 6464/5335/5782/2060/58513/7316/102/6714/867/998/6233/2885/5774/7311/1956/29924/3845/3265/5781/10254/5829/7314 22 Murine_minute_virus R-HSA-5654741 Signaling by FGFR3 19/2393 40/10654 4.118563751461926e-4 0.0012346477465232618 6.498146034332956e-4 6464/5335/5594/7316/6714/10818/8569/867/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 19 Murine_minute_virus R-HSA-171007 p38MAPK events 9/2393 13/10654 4.195039058734371e-4 0.0012519715676401017 6.589324040211062e-4 5899/9261/6714/5898/1432/5900/3845/3265/6300 9 Murine_minute_virus R-HSA-202670 ERKs are inactivated 9/2393 13/10654 4.195039058734371e-4 0.0012519715676401017 6.589324040211062e-4 1849/5594/5528/5519/5598/5518/5595/5515/5516 9 Murine_minute_virus R-HSA-1660514 Synthesis of PIPs at the Golgi membrane 11/2393 18/10654 4.6449883544863045e-4 0.0013831743100025885 7.279864789487306e-4 7179/5297/5286/55300/200576/377/22908/55697/5298/30849/4952 11 Murine_minute_virus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 29/2393 72/10654 5.05508023437674e-4 0.0015019528856019583 7.905015187378726e-4 1017/5684/246184/7321/5707/8697/5705/10197/7316/5695/890/5714/51433/5701/5708/5686/990/8900/51529/7324/64682/29945/10393/6233/51434/51343/7311/7314/996 29 Murine_minute_virus R-HSA-5205647 Mitophagy 15/2393 29/10654 5.343387910402876e-4 0.0015806048123487536 8.318972696572387e-4 1459/9140/8878/1460/9474/192111/7316/1457/6714/8408/81631/6233/9804/7311/7314 15 Murine_minute_virus R-HSA-5654732 Negative regulation of FGFR3 signaling 15/2393 29/10654 5.343387910402876e-4 0.0015806048123487536 8.318972696572387e-4 5594/7316/6714/10818/8569/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 15 Murine_minute_virus R-HSA-5693571 Nonhomologous End-Joining (NHEJ) 28/2393 69/10654 5.439863878539829e-4 0.0016024628266052636 8.434014876869808e-4 10111/51588/7518/7520/51720/472/7336/3981/580/5591/29086/64421/9656/22976/7341/10524/4683/55775/165918/8924/672/7158/9025/79184/7334/2547/79840/55183 28 Murine_minute_virus R-HSA-1059683 Interleukin-6 signaling 8/2393 11/10654 5.453157081582091e-4 0.0016024628266052636 8.434014876869808e-4 9021/6774/6772/867/3716/5781/3569/3572 8 Murine_minute_virus R-HSA-4755510 SUMOylation of immune response proteins 8/2393 11/10654 5.453157081582091e-4 0.0016024628266052636 8.434014876869808e-4 51588/8517/5970/4792/7341/7329/9641/4791 8 Murine_minute_virus R-HSA-1227986 Signaling by ERBB2 22/2393 50/10654 5.667302593666111e-4 0.0016617473688211354 8.746038783269132e-4 8065/6464/5335/5782/10273/207/5578/2064/7316/5753/6714/3320/2066/6233/2885/7311/1729/1956/3845/3265/11140/7314 22 Murine_minute_virus R-HSA-2871796 FCERI mediated MAPK activation 16/2393 32/10654 5.723208260234177e-4 0.0016708276838156423 8.793829914819168e-4 5601/6464/5335/5336/5594/4214/6850/4067/5609/2885/7410/3845/5599/3265/6416/5595 16 Murine_minute_virus R-HSA-917729 Endosomal Sorting Complex Required For Transport (ESCRT) 16/2393 32/10654 5.723208260234177e-4 0.0016708276838156423 8.793829914819168e-4 137492/25978/51160/27243/91782/79720/7316/51271/27183/6233/7311/93343/7251/10254/92421/7314 16 Murine_minute_virus R-HSA-432720 Lysosome Vesicle Biogenesis 17/2393 35/10654 5.957757608779208e-4 0.0017355206947313345 9.13431944595439e-4 164/351/8906/162/1777/9179/27243/1174/1785/9829/10717/1213/1211/8905/23431/3312/8907 17 Murine_minute_virus R-HSA-445144 Signal transduction by L1 12/2393 21/10654 6.002537267072055e-4 0.0017447722207975171 9.183011688407984e-4 5604/1459/5594/1460/4684/1457/5605/7410/3685/3897/1956/5595 12 Murine_minute_virus R-HSA-5696394 DNA Damage Recognition in GG-NER 18/2393 38/10654 6.067703976369506e-4 0.0017542619553168348 9.232957659562289e-4 9318/10445/7316/29844/1642/142/10987/1069/6233/7311/8607/5887/10038/5886/7508/7314/8451/7528 18 Murine_minute_virus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 18/2393 38/10654 6.067703976369506e-4 0.0017542619553168348 9.232957659562289e-4 163732/4869/51741/2064/5308/2099/4609/3329/7341/1387/7913/2033/7329/29028/1956/10765/8089/7528 18 Murine_minute_virus R-HSA-5654743 Signaling by FGFR4 19/2393 41/10654 6.074459307962772e-4 0.0017542619553168348 9.232957659562289e-4 6464/5335/5594/7316/6714/10818/8569/867/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 19 Murine_minute_virus R-HSA-68875 Mitotic Prophase 49/2393 142/10654 6.525364864845833e-4 0.0018804277244932079 9.89698802364846e-4 4000/23165/4928/5903/9631/91754/5862/2801/5578/5594/140609/348995/79023/9133/57122/23636/7443/10051/23511/10776/891/26003/983/8548/23279/4927/79902/5519/9883/23225/8086/64900/23399/79648/23592/23175/23133/9972/5518/5347/8021/6396/64689/6418/55746/8480/5595/5515/5516 49 Murine_minute_virus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 10/2393 16/10654 6.638530244199259e-4 0.0019048459373077102 0.0010025504933198475 57154/7316/7046/6233/7048/7311/56288/7040/57530/7314 10 Murine_minute_virus R-HSA-392517 Rap1 signalling 10/2393 16/10654 6.638530244199259e-4 0.0019048459373077102 0.0010025504933198475 5909/23108/5567/5908/7534/6494/5566/5894/5906/7529 10 Murine_minute_virus R-HSA-194138 Signaling by VEGF 39/2393 107/10654 6.797285752066889e-4 0.0019462313905490665 0.0010243323108152982 5170/5335/1495/1499/6461/5747/4690/5567/207/10458/5578/3315/3708/1500/9261/10768/10152/6714/64223/5566/8936/1432/10163/3320/3728/998/1398/79109/7410/2475/23191/3685/3710/9564/3845/3265/6300/5829/253260 39 Murine_minute_virus R-HSA-6804760 Regulation of TP53 Activity through Methylation 11/2393 19/10654 8.798857295964238e-4 0.002512558263350435 0.0013223990859739132 11200/472/7316/4194/2033/7157/91875/6233/7311/7314/4193 11 Murine_minute_virus R-HSA-1839126 FGFR2 mutant receptor activation 16/2393 33/10654 8.812704356527646e-4 0.002512558263350435 0.0013223990859739132 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/5439/5432/22916 16 Murine_minute_virus R-HSA-111885 Opioid Signalling 34/2393 91/10654 8.846194492679836e-4 0.002516751724032055 0.001324606170543187 3838/5321/5575/59345/5567/5578/5594/5142/112/3708/5573/5528/10768/10645/5566/5519/4988/2774/5576/5534/2783/2782/5613/5499/5577/1385/5144/5518/3710/1020/5141/2773/5515/5516 34 Murine_minute_virus R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 18/2393 39/10654 8.926113852592466e-4 0.0025341085937444713 0.001333741365128669 8841/22803/8237/10575/10528/63971/10517/7203/908/6774/26985/55294/10238/7157/10564/83752/54461/22948 18 Murine_minute_virus R-HSA-169893 Prolonged ERK activation events 9/2393 14/10654 9.403294351429917e-4 0.0026527188275612817 0.0013961678039796218 5604/5594/5605/10818/4914/1398/5906/7529/5595 9 Murine_minute_virus R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 9/2393 14/10654 9.403294351429917e-4 0.0026527188275612817 0.0013961678039796218 8841/79718/9611/2874/9612/5566/6907/3065/25942 9 Murine_minute_virus R-HSA-9005895 Pervasive developmental disorders 9/2393 14/10654 9.403294351429917e-4 0.0026527188275612817 0.0013961678039796218 8841/79718/9611/2874/9612/5566/6907/3065/25942 9 Murine_minute_virus R-HSA-113510 E2F mediated regulation of DNA replication 12/2393 22/10654 0.0010519467100499114 0.002955154279804783 0.0015553443577919909 7027/5422/1869/891/983/84515/5519/5518/23649/5001/5515/5516 12 Murine_minute_virus R-HSA-198753 ERK/MAPK targets 12/2393 22/10654 0.0010519467100499114 0.002955154279804783 0.0015553443577919909 1849/5594/5528/4205/5519/5598/1432/6196/5518/5595/5515/5516 12 Murine_minute_virus R-HSA-157579 Telomere Maintenance 31/2393 82/10654 0.0011705575950113306 0.0032814794504501736 0.0017270944476053545 7014/6118/2237/55651/7015/1763/57804/5982/54107/7013/3978/5422/10856/5425/5111/56655/5426/6119/1736/5427/5985/65057/5984/23649/8607/5983/6117/5981/10714/54386/5424 31 Murine_minute_virus R-HSA-5358351 Signaling by Hedgehog 50/2393 149/10654 0.0011754637535649679 0.0032864060948098626 0.0017296874183209804 8454/57154/8945/84617/5684/2735/5575/54903/6608/5707/5567/22873/1452/10382/6500/409/79577/112/7277/10381/5705/10197/64750/5573/7316/5695/2778/5727/8650/5714/7415/5566/8405/2932/5701/5576/347733/5708/5686/10376/6400/83737/5577/6233/7311/10383/23432/8481/7280/7314 50 Murine_minute_virus R-HSA-1643713 Signaling by EGFR in Cancer 13/2393 25/10654 0.0011773861199661237 0.0032864060948098626 0.0017296874183209804 6464/5335/7316/867/3320/6233/2885/7311/1956/3845/3265/11140/7314 13 Murine_minute_virus R-HSA-6790901 rRNA modification in the nucleus and cytosol 25/2393 62/10654 0.0011796726355250329 0.0032864060948098626 0.0017296874183209804 2091/6203/55651/55813/6194/25879/55226/9277/56902/10528/84135/27340/51602/51096/1736/51077/10171/5822/23160/6201/51202/6187/6208/10885/10813 25 Murine_minute_virus R-HSA-165159 mTOR signalling 18/2393 40/10654 0.001285956393533565 0.003567317548022209 0.001877535551590636 6194/207/84335/7249/58528/6198/29904/64223/6794/1981/6009/1977/1975/2475/92335/1978/57521/7529 18 Murine_minute_virus R-HSA-5674135 MAP2K and MAPK activation 18/2393 40/10654 0.001285956393533565 0.003567317548022209 0.001877535551590636 5604/8844/5594/409/5908/7414/6714/5605/2335/5894/8826/5906/4140/3845/3265/369/7529/5595 18 Murine_minute_virus R-HSA-8934593 Regulation of RUNX1 Expression and Activity 10/2393 17/10654 0.0012884938009274248 0.003567317548022209 0.001877535551590636 27161/57690/6714/1021/595/192669/861/5371/26523/5781 10 Murine_minute_virus R-HSA-2122948 Activated NOTCH1 Transmits Signal to the Nucleus 15/2393 31/10654 0.0013054509091974334 0.0035986743208029303 0.0018940391162120688 142678/113878/23220/409/7316/3714/8650/102/83737/92737/6233/7311/57534/4851/7314 15 Murine_minute_virus R-HSA-5654733 Negative regulation of FGFR4 signaling 15/2393 31/10654 0.0013054509091974334 0.0035986743208029303 0.0018940391162120688 5594/7316/6714/10818/8569/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 15 Murine_minute_virus R-HSA-446203 Asparagine N-linked glycosylation 91/2393 304/10654 0.0013091193515485115 0.0035986743208029303 0.0018940391162120688 9919/84364/22820/84617/6711/11014/6483/10342/6712/2673/55291/79796/1783/8703/5373/51014/79139/9761/79053/2801/10484/10382/10802/347688/821/830/811/7277/10381/9945/4249/1780/1604/9554/377/1781/7316/7264/9570/22872/5589/8655/1315/11196/1639/6484/832/7415/55738/4597/11316/4124/6675/22870/100302736/347733/10376/6400/10972/51143/1314/9632/23243/2683/6233/9276/6709/5537/7311/9871/27095/7109/10383/9334/5887/6396/84342/26286/1453/64689/267/26958/140735/7280/10427/54732/7314/51164/1778/22818/372 91 Murine_minute_virus R-HSA-170968 Frs2-mediated activation 8/2393 12/10654 0.001313247569307935 0.0035986743208029303 0.0018940391162120688 5604/5594/5605/10818/4914/5906/7529/5595 8 Murine_minute_virus R-HSA-5689877 Josephin domain DUBs 8/2393 12/10654 0.001313247569307935 0.0035986743208029303 0.0018940391162120688 4287/7316/7415/6233/7311/5887/5886/7314 8 Murine_minute_virus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 25/2393 63/10654 0.0015446775342106314 0.004224220195596421 0.002223273787156011 5684/246184/7321/5707/8697/5705/10197/7316/5695/5714/51433/5701/5708/5686/51529/7324/64682/29945/10393/6233/51434/51343/7311/7314/996 25 Murine_minute_virus R-HSA-3232118 SUMOylation of transcription factors 11/2393 20/10654 0.0015604015600371327 0.00425852971578362 0.0022413314293598004 1029/9112/51588/3090/6613/7341/7157/7329/7158/4286/4193 11 Murine_minute_virus R-HSA-110056 MAPK3 (ERK1) activation 7/2393 10/10654 0.0017909300948406042 0.004838399852996793 0.0025465262384193653 5604/983/3716/5781/3569/3572/5595 7 Murine_minute_virus R-HSA-2465910 MASTL Facilitates Mitotic Progression 7/2393 10/10654 0.0017909300948406042 0.004838399852996793 0.0025465262384193653 10776/891/983/5519/5518/5515/5516 7 Murine_minute_virus R-HSA-5602498 MyD88 deficiency (TLR2/4) 7/2393 10/10654 0.0017909300948406042 0.004838399852996793 0.0025465262384193653 23643/10333/7099/4615/7096/929/7097 7 Murine_minute_virus R-HSA-74749 Signal attenuation 7/2393 10/10654 0.0017909300948406042 0.004838399852996793 0.0025465262384193653 3643/6464/5594/2885/8660/5595/2887 7 Murine_minute_virus R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 7/2393 10/10654 0.0017909300948406042 0.004838399852996793 0.0025465262384193653 2308/2309/4303/1387/10628/2033/23411 7 Murine_minute_virus R-HSA-74158 RNA Polymerase III Transcription 18/2393 41/10654 0.0018169645817627427 0.004889021163779267 0.0025731690335680352 55718/5434/5440/2976/5451/9330/4774/5441/51082/5435/9328/5437/4782/10302/661/6619/4784/6618 18 Murine_minute_virus R-HSA-749476 RNA Polymerase III Abortive And Retractive Initiation 18/2393 41/10654 0.0018169645817627427 0.004889021163779267 0.0025731690335680352 55718/5434/5440/2976/5451/9330/4774/5441/51082/5435/9328/5437/4782/10302/661/6619/4784/6618 18 Murine_minute_virus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 26/2393 67/10654 0.0018365050723399253 0.004921833593871 0.0025904387336163153 5684/246184/7321/5707/991/8697/5705/10197/7316/5695/5714/51433/5701/5708/5686/51529/7324/64682/29945/10393/9232/6233/51434/7311/7314/996 26 Murine_minute_virus R-HSA-73856 RNA Polymerase II Transcription Termination 26/2393 67/10654 0.0018365050723399253 0.004921833593871 0.0025904387336163153 10921/7919/6432/6431/6430/134353/6428/8106/22794/81608/4686/65109/84321/1478/10898/10569/10189/9295/23283/6634/9775/6427/6426/22916/1479/6628 26 Murine_minute_virus R-HSA-2691230 Signaling by NOTCH1 HD Domain Mutants in Cancer 9/2393 15/10654 0.0018832977618204953 0.004997265348196958 0.0026301396569457674 142678/7316/3714/102/6233/7311/57534/4851/7314 9 Murine_minute_virus R-HSA-2691232 Constitutive Signaling by NOTCH1 HD Domain Mutants 9/2393 15/10654 0.0018832977618204953 0.004997265348196958 0.0026301396569457674 142678/7316/3714/102/6233/7311/57534/4851/7314 9 Murine_minute_virus R-HSA-430039 mRNA decay by 5' to 3' exoribonuclease 9/2393 15/10654 0.0018832977618204953 0.004997265348196958 0.0026301396569457674 1656/80153/23644/27257/25804/219988/55802/196513/54464 9 Murine_minute_virus R-HSA-5637810 Constitutive Signaling by EGFRvIII 9/2393 15/10654 0.0018832977618204953 0.004997265348196958 0.0026301396569457674 6464/5335/867/3320/2885/1956/3845/3265/11140 9 Murine_minute_virus R-HSA-5637812 Signaling by EGFRvIII in Cancer 9/2393 15/10654 0.0018832977618204953 0.004997265348196958 0.0026301396569457674 6464/5335/867/3320/2885/1956/3845/3265/11140 9 Myxoma_virus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 294/1217 309/10654 2.851349467405583e-268 3.512862543843678e-265 2.0559730370240256e-265 8454/9354/57154/5718/197131/23352/5689/26224/8945/10293/51088/140460/5684/79754/6737/8065/64410/127544/114088/5720/11065/285231/221687/9666/84937/57531/142678/55070/5682/84708/246184/146330/55819/51320/93611/54850/7319/142686/8916/79791/26046/151636/5700/122706/7321/5707/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/8697/7320/5690/26235/10477/9817/10193/148581/9039/223082/92912/154881/5717/140739/25897/9491/23198/6500/6478/150726/390594/10533/81559/144699/143471/5706/140462/5705/26259/57674/10197/53339/154214/7336/200845/79876/26263/64750/51619/6477/9690/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/10213/5709/9604/9978/22888/5695/23304/7317/80196/114907/140456/64718/54926/4008/7335/84861/11059/55236/84085/55958/54620/4734/84078/7337/5714/26272/84676/27252/51444/7704/8651/3093/26118/222235/51433/9861/25831/7322/5715/64219/10489/5711/23327/9867/26249/140458/55905/5701/5688/55336/5687/26270/143279/51465/63893/89122/6502/23291/118424/5685/10616/5683/5698/5708/27246/5692/5686/89910/5713/55521/25898/9903/201456/55294/5699/26190/55008/7328/79654/5710/10422/84727/135892/7428/5702/22954/8453/401036/83737/51529/9040/90933/140461/7324/63891/5719/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/5704/6233/90135/56658/9870/51434/6468/26267/142685/5716/25847/90025/7327/10425/51343/25793/7311/26091/23295/6047/84541/7318/23194/51666/90293/131405/55175/55284/868/54461/9320/80204/136371/26232/29882/57520/26234/127247/27338/7334/92591/5930/11275/5694/55182/84961/4591/23014/29116/26268/92369/115290/90678/51725/140459/5693/5721/5696/997/23608/51676/55585/64320/5691/84261/51132/7325/57542/9820/55658/7314/996/10324/283807/140691/899 294 Myxoma_virus R-HSA-983169 Class I MHC mediated antigen processing & presentation 304/1217 371/10654 3.9652473750389995e-231 2.4425923830240238e-228 1.4295760273166921e-228 8454/9354/57154/1147/5718/197131/23352/5689/26224/8945/10293/51088/140460/5684/79754/6737/8065/64410/127544/114088/5720/11065/285231/221687/9666/84937/57531/142678/55070/5682/84708/246184/146330/55819/51320/93611/54850/7319/142686/8916/79791/26046/151636/5700/122706/7321/5707/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/10484/8697/7320/5690/26235/10477/9817/10193/148581/9039/223082/92912/154881/5717/140739/25897/9491/23198/6500/6478/150726/390594/10533/81559/144699/143471/5706/140462/5705/26259/57674/10333/10197/53339/7099/8517/154214/7336/200845/4615/79876/26263/64750/51619/6477/9690/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/10213/5709/9604/9978/22888/5695/23304/7317/80196/114907/140456/64718/54926/4008/7335/7096/84861/11059/55236/84085/55958/54620/4734/84078/7337/5714/26272/84676/27252/51444/7704/8651/3093/26118/222235/51433/9861/25831/7322/5715/64219/10489/5711/23327/9867/26249/140458/55905/5701/5688/55336/5687/26270/143279/51465/63893/89122/6502/23291/118424/5685/10616/5683/3309/5698/5708/27246/5692/5686/89910/5713/55521/25898/9903/201456/55294/5699/26190/55008/7328/79654/5710/10422/84727/135892/7428/5702/22954/8453/401036/83737/51529/9040/90933/140461/7324/63891/5719/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/5704/6233/90135/56658/9870/51434/6468/26267/142685/5716/25847/90025/7327/10425/51343/25793/7311/26091/23295/6047/84541/7318/23194/51666/90293/131405/55175/55284/868/54461/9320/80204/136371/26232/29882/57520/26234/127247/27338/7334/92591/5930/11275/5694/55182/7097/84961/4591/3551/23014/29116/26268/92369/115290/90678/51725/140459/5693/5721/5696/997/23608/51676/55585/64320/5691/84261/51132/7325/57542/9820/55658/7314/996/10324/283807/140691/899 304 Myxoma_virus R-HSA-8951664 Neddylation 200/1217 234/10654 2.1365854524467538e-156 8.774244258048002e-154 5.135301876933426e-154 8454/9318/5718/51397/5689/26224/54165/8945/56995/23412/51088/9655/140460/5684/79754/8065/64410/5720/149951/29099/285231/11091/5682/146330/93611/54850/142686/55884/79791/5700/122706/7321/5707/51665/9616/122769/9021/4738/5690/26235/9817/9039/154881/5717/140739/9491/23198/6500/150726/390594/144699/143471/5706/140462/28952/5705/26259/10197/53339/28991/200845/26263/140825/8452/7323/9306/10517/89890/142689/7316/10213/5709/9978/5695/114907/140456/4008/84861/64708/84085/55958/54620/84078/5714/55527/26272/27252/7704/26118/222235/10980/9861/7322/5715/122416/10489/5711/26249/140458/5701/5688/55336/5687/26270/6502/23291/170622/5685/90864/5683/55832/5698/5708/1642/5692/10920/5686/5713/9903/201456/55294/5699/26190/5710/84727/10987/7428/5702/8453/123879/401036/9040/140461/5719/79176/80176/8139/23142/126433/10116/5704/26043/6233/90135/6468/123228/2873/26267/142685/5716/25793/7311/1154/84541/23194/51666/90293/55175/8533/54461/80204/136371/26232/8835/26234/127247/8883/92591/11275/5694/51122/84961/54939/23014/26268/92369/115290/54951/51725/140459/5693/55208/5721/84259/5696/51676/5691/84261/150684/50813/57542/9820/7314/51514/51138/10324/8451/56929/283807/899 200 Myxoma_virus R-HSA-418594 G alpha (i) signalling events 236/1217 406/10654 2.096045159368801e-121 6.455819090855907e-119 3.7783971951779704e-119 729230/2788/151/57007/10316/10803/2913/4544/4543/126006/10663/4889/3838/1880/26086/9283/727/351/11251/7852/9294/54331/3352/8484/50833/29899/338398/5726/117579/283869/338442/3579/59345/63940/4986/23566/6351/2358/2916/64805/2770/6752/259293/6374/1237/5539/259287/1903/2852/2550/84539/50836/1230/5594/50832/5179/3354/6753/846/4886/2841/2919/3577/2918/4987/51289/10681/5368/6754/8862/51764/259294/112/94235/114/259290/301/8811/6383/2912/108/3576/56670/6360/5196/3827/150/113/5173/56923/2832/5528/2357/4985/27199/2920/2826/55970/2921/1236/2853/6352/140/6751/6376/259295/165140/27198/111/107/5443/9568/186/3627/53637/2792/54429/346562/6714/2840/2831/3361/6346/152/6364/5367/80834/10563/5519/134/5540/4988/259292/1901/6370/58191/2793/5030/5697/6755/1524/5733/256933/1129/643/10850/51083/2785/3355/2783/624/3351/2784/4852/2782/1233/6288/6372/6366/2786/5499/50834/339403/2861/259285/2771/728/50838/2914/10022/5473/183/4283/8843/719/2847/6363/6373/57121/2917/2833/1268/9290/11255/50831/5518/9170/6382/187/1132/2359/1814/10874/50839/83756/80835/6357/196883/6750/9672/115/259296/8698/259289/56477/5660/50835/801/1815/2587/1325/53829/1232/9934/50840/1902/259286/3350/129521/1234/50837/2791/109/1269/59340/50865/4887/2773/2790/805/5515/718/2787/6387/623/5516 236 Myxoma_virus R-HSA-500792 GPCR ligand binding 216/1217 468/10654 2.1899968868741727e-84 5.396152329257961e-82 3.158206036860649e-82 729230/2788/151/2532/57007/10316/10803/2913/4544/4543/2149/10663/4889/1880/9283/727/351/11251/7852/9294/54331/3352/8484/50833/338398/5726/117579/283869/338442/3579/59345/4986/23566/6351/2358/2916/64805/6863/6752/259293/6374/1237/5539/259287/1903/2852/2550/84539/50836/1230/50832/5179/3354/6753/846/4886/2841/2919/3577/2918/4987/51289/10681/5368/6754/8862/51764/259294/94235/259290/301/8811/2912/3576/56670/6360/5196/3827/150/5173/56923/2832/2357/4985/27199/2920/2826/55970/2921/1236/5727/2853/6352/140/6751/6376/259295/165140/27198/5443/6348/9568/186/6354/3627/53637/2792/54429/2840/2831/3361/6346/152/6364/5367/80834/10563/134/5540/4988/259292/1901/6370/58191/2793/5030/5697/6755/1524/5733/256933/1129/643/10850/51083/2785/3355/2783/624/3351/2784/2829/4852/2782/1233/6288/6372/6366/185/2786/50834/339403/2861/259285/728/50838/2914/10022/5473/183/4283/8843/719/2847/6363/6373/57121/2917/2833/6347/1268/9290/11255/50831/9170/187/1132/2359/1814/10874/50839/83756/80835/6357/6356/6750/259296/8698/259289/56477/5660/50835/1815/2587/1325/53829/1232/9934/50840/1902/259286/3350/129521/1234/50837/2791/1269/59340/1813/50865/4887/2790/718/2787/6387/623 216 Myxoma_virus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 121/1217 171/10654 8.697480598484634e-76 1.785882682888845e-73 1.045223545607364e-73 10921/6158/5718/5689/6138/6144/6203/5684/6227/9349/4736/5720/6206/6194/6234/6191/6128/5682/51121/6132/6147/6217/5700/122706/5707/6230/6222/6176/6152/5690/6136/6125/5717/9491/23198/6224/6146/6141/26986/143471/6202/5706/5705/10197/6232/6169/6160/6164/4686/7316/6155/10213/5709/6175/9978/6218/5695/6209/5714/6193/6210/6229/11224/6205/6165/9861/5715/6142/5711/6204/5701/5688/6228/23521/5687/5685/5683/5698/5708/5692/5686/5713/140801/6156/5699/6143/5710/6181/6124/5702/8453/6207/5719/5704/6233/5716/7311/6223/25873/3921/6188/6189/9775/6135/6201/6161/5694/9045/6187/6168/22916/5693/6208/6157/5721/6137/5696/5691/6122/6133/7314 121 Myxoma_virus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 76/1217 80/10654 2.9671243623620758e-67 5.222138877757254e-65 3.0563611852902586e-65 8454/5718/1017/5689/8945/26271/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/6500/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 76 Myxoma_virus R-HSA-373076 Class A/1 (Rhodopsin-like receptors) 163/1217 335/10654 3.398169936919551e-67 5.233181702856109e-65 3.0628242194603854e-65 729230/151/2532/57007/10316/10803/4544/4543/2149/10663/4889/1880/9283/727/351/11251/7852/9294/3352/8484/117579/283869/338442/3579/4986/23566/6351/2358/64805/6863/6752/6374/1237/5539/1903/2852/84539/1230/5179/3354/6753/4886/2841/2919/3577/4987/51289/5368/6754/8862/301/8811/3576/56670/6360/5196/3827/150/5173/56923/2832/2357/4985/27199/2920/2826/2921/1236/2853/6352/140/6751/6376/165140/27198/5443/6348/186/6354/3627/53637/2840/2831/3361/6346/152/6364/5367/10563/134/5540/4988/1901/6370/58191/5030/5697/6755/1524/5733/256933/1129/643/10850/51083/3355/624/3351/2829/4852/1233/6288/6372/6366/185/339403/2861/728/10022/5473/183/4283/8843/719/2847/6363/6373/57121/2833/6347/1268/9290/11255/9170/187/1132/2359/1814/10874/6357/6356/6750/8698/56477/5660/1815/2587/1325/53829/1232/9934/1902/3350/129521/1234/1269/59340/1813/50865/4887/718/6387/623 163 Myxoma_virus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 79/1217 86/10654 9.01681273691851e-67 1.1108713291883604e-64 6.5015965524096634e-65 8454/5718/1017/5689/8945/26271/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/6500/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/983/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/9232/5704/6233/51434/5716/51343/7311/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 79 Myxoma_virus R-HSA-453276 Regulation of mitotic cell cycle 79/1217 86/10654 9.01681273691851e-67 1.1108713291883604e-64 6.5015965524096634e-65 8454/5718/1017/5689/8945/26271/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/6500/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/983/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/9232/5704/6233/51434/5716/51343/7311/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 79 Myxoma_virus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 71/1217 72/10654 1.2811934223444107e-66 1.43493663302574e-64 8.398253534027957e-65 5718/1017/5689/9134/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/5717/9491/23198/898/143471/5706/5705/10197/8881/7316/10213/5709/5695/890/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/990/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 71 Myxoma_virus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 70/1217 72/10654 3.748199711760088e-64 3.8481517040736905e-62 2.252207721540053e-62 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/9232/5704/6233/51434/5716/51343/7311/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 70 Myxoma_virus R-HSA-376176 Signaling by ROBO receptors 125/1217 218/10654 4.0568275993683334e-62 3.844624309555221e-60 2.250143243374339e-60 10921/6158/5718/5689/6138/6144/6203/5684/6227/9349/4736/7852/5720/6206/6194/6234/6191/6128/5682/51121/6132/6147/6217/5700/122706/5707/6230/6222/6176/6152/5690/6136/6125/5717/9491/23198/6224/6146/6141/26986/143471/6202/5706/5705/10197/6232/6169/6160/6164/4686/7316/6155/10213/5709/6175/9978/6218/5695/6209/5714/6193/6714/6210/6229/11224/6205/6165/9861/5715/6142/5711/6204/5701/5688/6228/23521/5687/5685/5683/5698/5708/5692/5686/5713/7408/140801/6156/5699/6143/5710/6181/6124/5702/8453/6207/5719/5704/6233/5716/7311/6223/25873/3921/6188/6189/9775/6135/6201/6161/5694/9045/6187/6168/22916/5693/6208/6157/5721/6137/5696/5691/6122/6133/7314/6387 125 Myxoma_virus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 66/1217 67/10654 7.91171795240366e-62 6.962311798115221e-60 4.0748321784936145e-60 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/9232/5704/6233/51434/5716/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 66 Myxoma_virus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 71/1217 76/10654 2.0924482397057283e-61 1.7185974875449716e-59 1.0058435397883676e-59 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/9232/5704/6233/51434/5716/7311/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 71 Myxoma_virus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 70/1217 75/10654 1.8031663387747977e-60 1.3884380808565942e-58 8.126111460925899e-59 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/9232/5704/6233/51434/5716/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 70 Myxoma_virus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 68/1217 72/10654 1.021760075036965e-59 7.404755367326712e-58 4.3337811232218025e-58 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/890/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 68 Myxoma_virus R-HSA-69052 Switching of origins to a post-replicative state 77/1217 90/10654 1.207845306915804e-59 8.26703010066817e-58 4.8384446505106776e-58 8454/5718/1017/5689/9134/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/5717/9491/23198/6500/898/143471/5706/5705/10197/8881/7316/10213/5709/9978/5695/890/5714/51433/9861/5715/4998/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/990/5713/119504/5699/5710/81620/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 77 Myxoma_virus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 68/1217 73/10654 1.3321570658778502e-58 8.637986869271112e-57 5.0555545159353326e-57 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/890/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 68 Myxoma_virus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 62/1217 63/10654 5.2847176783669955e-58 3.255386089874069e-56 1.9052797945691538e-56 5718/5689/5684/5720/11065/5682/246184/5700/7321/5707/8697/5690/5717/9491/5706/5705/10197/8881/7316/10213/5709/5695/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 62 Myxoma_virus R-HSA-375276 Peptide ligand-binding receptors 115/1217 201/10654 5.532904995540997e-57 3.2459709307173845e-55 1.8997693844338765e-55 729230/2532/57007/10316/10803/2149/10663/4889/9283/727/351/7852/8484/117579/283869/3579/4986/6351/2358/6863/6752/6374/1237/5539/2852/84539/1230/5179/6753/4886/2919/3577/4987/51289/5368/6754/8862/301/8811/3576/6360/5196/3827/5173/56923/2832/2357/4985/2920/2826/2921/1236/6352/6751/6376/5443/6348/186/6354/3627/2831/6346/6364/5367/10563/5540/4988/6370/58191/5697/6755/1524/256933/643/10850/51083/624/2829/4852/1233/6288/6372/6366/185/339403/2861/728/10022/5473/183/4283/719/2847/6363/6373/2833/6347/187/2359/10874/6357/6356/6750/56477/5660/2587/1325/1232/129521/1234/50865/4887/718/6387/623 115 Myxoma_virus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 59/1217 60/10654 3.863083100989744e-55 2.163326536554257e-53 1.266130107262189e-53 8454/1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/9039/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/9020/5970/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5971/5694/5693/5721/5696/5691/4791/7314 59 Myxoma_virus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 58/1217 59/10654 3.4727069680889086e-54 1.860163036819798e-52 1.0886976078448067e-52 8454/1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/9039/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/9020/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5971/5694/5693/5721/5696/5691/4791/7314 58 Myxoma_virus R-HSA-69242 S Phase 99/1217 161/10654 3.633017929670596e-53 1.8649492038975725e-51 1.0914988078177013e-51 8454/5718/1017/6118/5689/9134/1019/5684/994/5720/11065/5682/246184/7027/5700/122706/7321/5707/207/8697/5690/5717/1027/9491/23198/6500/898/143471/5706/5705/10197/8881/5934/7316/10213/5709/9978/1869/1875/993/5695/890/1026/5714/5111/4609/51433/9861/5715/4998/6119/5711/2932/5701/5688/5687/6502/5685/5683/5698/5708/10000/5692/5686/990/5713/119504/1874/595/5699/5710/81620/5702/8900/51529/7324/5719/64682/29945/10393/208/5704/6233/51434/5716/51343/7311/25906/6117/29882/5694/1163/5424/5693/5721/5696/5691/7314/996 99 Myxoma_virus R-HSA-156842 Eukaryotic Translation Elongation 74/1217 93/10654 8.510187087674457e-53 4.1938201968059727e-51 2.4545171179187385e-51 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/1917/1938/6147/1915/6217/1936/6230/6222/6176/6152/6136/6125/1937/6224/6146/6141/6202/6232/6169/6160/6164/6155/6175/6218/1933/6209/6193/6210/6229/11224/6205/6165/6142/6204/6228/23521/140801/6156/6143/6181/6124/6207/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133 74 Myxoma_virus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 58/1217 60/10654 9.297826804979389e-53 4.405739470667157e-51 2.578547109882948e-51 8454/5718/1017/5689/9134/1019/5684/5720/5682/5700/5707/5690/5717/1027/9491/6500/898/5706/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/595/5699/5710/5702/8900/5719/5704/6233/5716/7311/5694/1163/5693/5721/5696/5691/7314 58 Myxoma_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 70/1217 85/10654 6.065097760148273e-52 2.767481644630619e-50 1.6197239632364783e-50 8454/5718/1017/5689/9134/1019/5684/994/5720/5682/7027/5700/5707/207/5690/5717/1027/9491/6500/898/5706/5705/10197/5934/7316/10213/5709/1869/1875/993/5695/890/1026/5714/4609/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/10000/5692/5686/5713/1874/595/5699/5710/5702/8900/5719/208/5704/6233/5716/51343/7311/5694/1163/5693/5721/5696/5691/7314 70 Myxoma_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 71/1217 88/10654 1.7892641175487006e-51 7.872762117214282e-50 4.607691430529548e-50 5393/5718/3303/5689/5684/5720/5682/23404/5073/5700/122706/5707/207/5690/3184/5717/9491/23198/26986/143471/5706/5705/10197/7534/7316/10213/5709/5695/5714/9861/5715/5711/1432/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/51013/5702/5719/5704/6233/5716/7311/11340/51010/5600/5694/56915/3304/3312/8570/23016/5693/54512/5721/5696/5691/118460/167227/22894/7314/1994 71 Myxoma_virus R-HSA-1169091 Activation of NF-kappaB in B cells 61/1217 67/10654 4.346507871998715e-51 1.846516447690489e-49 1.080710668718374e-49 8454/1147/5718/5689/8945/5684/5720/4790/5966/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/8517/7316/10213/5709/5695/5970/4792/4793/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/4794/5694/3551/5693/5721/5696/5691/7314 61 Myxoma_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 68/1217 82/10654 7.039820646282552e-51 2.8910196787400348e-49 1.6920270676152802e-49 8454/5718/5689/8945/5684/5720/5682/1499/5525/5700/139285/122706/5707/5526/1452/5690/5717/9491/23198/6500/143471/5706/5705/10197/5528/7316/10213/5709/9978/5695/5714/6934/9861/5715/5519/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/324/5699/8312/5529/5710/5702/5719/5704/6233/5527/5716/7311/5518/5694/5693/5721/5696/5691/7314/5515/5516 68 Myxoma_virus R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 54/1217 55/10654 2.2438064974487103e-50 8.917321305989714e-49 5.2190405798043014e-49 8454/5718/5689/8945/26271/5684/5720/5682/5700/122706/5707/991/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/51343/7311/5694/5693/5721/5696/5691/7314 54 Myxoma_virus R-HSA-69202 Cyclin E associated events during G1/S transition 68/1217 83/10654 3.478301110037752e-50 1.3391459273645345e-48 7.837619277552172e-49 8454/5718/1017/5689/9134/1019/5684/5720/5682/7027/5700/5707/207/5690/5717/1027/9491/6500/898/5706/5705/10197/5934/7316/10213/5709/1869/1875/993/5695/890/1026/5714/4609/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/10000/5692/5686/5713/1874/595/5699/5710/5702/8900/5719/208/5704/6233/5716/7311/5694/1163/5693/5721/5696/5691/7314 68 Myxoma_virus R-HSA-69239 Synthesis of DNA 82/1217 119/10654 6.125946755704363e-50 2.287020122129629e-48 1.338524251246408e-48 8454/5718/1017/6118/5689/9134/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/5717/9491/23198/6500/898/143471/5706/5705/10197/8881/7316/10213/5709/9978/5695/890/5714/5111/51433/9861/5715/4998/6119/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/990/5713/119504/5699/5710/81620/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/6117/29882/5694/5424/5693/5721/5696/5691/7314/996 82 Myxoma_virus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 53/1217 54/10654 2.0062644926558817e-49 7.269758396917782e-48 4.2547714472733093e-48 8454/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/6790/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/23194/5694/5693/5721/5696/5691/7314 53 Myxoma_virus R-HSA-156902 Peptide chain elongation 70/1217 89/10654 2.4299950665090518e-49 8.553582634111863e-48 5.0061552498006037e-48 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/1938/6147/1915/6217/6230/6222/6176/6152/6136/6125/6224/6146/6141/6202/6232/6169/6160/6164/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6142/6204/6228/23521/140801/6156/6143/6181/6124/6207/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133 70 Myxoma_virus R-HSA-5610783 Degradation of GLI2 by the proteasome 56/1217 60/10654 1.7005943532379028e-48 5.662519576186747e-47 3.314102793649967e-47 8454/5718/5689/8945/5684/5720/5682/5700/122706/5707/1452/51684/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/2736/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 56 Myxoma_virus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 56/1217 60/10654 1.7005943532379028e-48 5.662519576186747e-47 3.314102793649967e-47 8454/5718/5689/8945/5684/5720/5682/5700/122706/5707/1452/51684/5690/5717/9491/23198/6500/143471/5706/5705/10197/2737/7316/10213/5709/9978/5695/5714/9861/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 56 Myxoma_virus R-HSA-69615 G1/S DNA Damage Checkpoints 60/1217 68/10654 2.3475379233020417e-48 7.610965056600303e-47 4.454469466653459e-47 5718/1017/5689/9134/5684/5720/5682/5700/122706/5707/5690/5717/1027/9491/23198/898/11200/143471/5706/5705/10197/7316/10213/5709/993/5695/890/1026/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/7157/8900/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314/4193 60 Myxoma_virus R-HSA-5663205 Infectious disease 152/1217 383/10654 3.59454544771629e-48 1.1355076901503768e-46 6.645785780528094e-47 6158/5718/3303/5689/6138/8945/6144/3838/6203/5684/5903/6227/9349/8065/4736/2926/7852/5720/6206/6194/6234/6191/6128/5682/51121/6132/1499/1938/6147/6217/5700/122706/5707/5430/6230/6222/6176/6152/5690/6136/7518/8106/6125/5717/4869/9491/23198/6500/6749/6224/6146/6141/143471/6202/5706/5705/10197/6232/6169/6160/6164/4686/7316/6155/10213/5709/6175/9978/293/6218/5695/292/3055/6209/5714/6193/6714/6210/6229/11224/8148/6205/6165/8731/9861/5715/6142/5711/6204/23327/5701/5688/6228/23521/5687/999/5685/5683/5698/5708/3320/5692/5686/5713/140801/6156/5699/6143/5710/6181/6124/5702/6207/5478/5719/3836/5704/6233/3326/5716/1025/7311/6223/25873/1213/3921/6188/6189/6135/6201/6161/5694/3304/801/9045/6187/6168/22916/5693/6208/1234/6157/5721/6137/5696/5691/8480/6122/6133/940/7314/805 152 Myxoma_virus R-HSA-449147 Signaling by Interleukins 169/1217 461/10654 5.215198379940377e-48 1.6062811010216362e-46 9.40108129015568e-47 729230/8454/3605/3557/7124/1147/5718/834/5689/3725/8945/1326/9655/5684/351/5720/1437/3667/4790/6597/5682/90865/7412/5700/6351/3578/122706/7184/5707/207/9021/7422/29110/5690/3553/1230/5594/8878/5717/2919/9491/23198/6500/3082/5743/143471/4318/5706/4312/3383/5705/301/9987/10197/8517/3576/4615/7534/3313/5528/2357/4313/7316/3565/4985/10213/5709/6175/9978/2920/5695/79155/6352/3185/6774/4314/7335/5970/4792/3055/5443/1026/6348/1440/4793/3627/5714/3606/6772/8651/4609/9861/6364/5715/5519/5711/4988/1901/3552/1432/5701/5688/3567/5687/3558/4067/3717/23291/4088/598/2247/5685/5683/5698/5708/3320/5692/5686/5713/2335/595/5699/5710/3458/3181/6288/5702/7157/5478/5719/3654/5704/6233/5716/2353/7311/1154/6363/6347/7076/5518/6382/9235/8835/5599/5600/7431/7334/6356/3600/5694/3312/3574/3551/3569/3162/4170/5693/1234/5721/5696/3586/5691/4791/7314/3596/5595/5515/5516 169 Myxoma_virus R-HSA-192823 Viral mRNA Translation 69/1217 89/10654 6.993477451100993e-48 2.101454687745469e-46 1.2299183707327806e-46 6158/6138/6144/6203/6227/9349/4736/2926/6206/6194/6234/6191/6128/51121/6132/6147/6217/6230/6222/6176/6152/6136/6125/6224/6146/6141/6202/6232/6169/6160/6164/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6142/6204/6228/23521/140801/6156/6143/6181/6124/6207/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133 69 Myxoma_virus R-HSA-9013694 Signaling by NOTCH4 66/1217 82/10654 9.004637979596697e-48 2.641360474015031e-46 1.5459090265723654e-46 8454/5718/5689/5684/5720/5682/2648/5700/5707/207/5690/55534/3280/5717/9491/6500/84441/5706/5705/10197/10046/7534/7316/10213/5709/9978/5695/5714/9861/5715/22938/8850/5711/5701/5688/1387/5687/4088/5685/5683/5698/5708/59/5692/5686/5713/2033/4855/55294/5699/5710/5702/5719/9794/5704/6233/5716/7311/5694/3516/4851/5693/5721/5696/5691/7314 66 Myxoma_virus R-HSA-69306 DNA Replication 83/1217 127/10654 1.0122701475854218e-47 2.900271678663348e-46 1.697441985547158e-46 8454/5718/1017/6118/5689/9134/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/5717/9491/23198/6500/898/143471/5706/5705/10197/8881/7316/10213/5709/9978/1869/5695/890/5714/5111/51433/9861/5715/4998/6119/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/990/5713/119504/5699/5710/81620/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/6117/29882/5694/5424/5693/5721/5696/5691/7314/996 83 Myxoma_virus R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 51/1217 52/10654 1.598629269536924e-47 4.190449489509554e-46 2.452544344082403e-46 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Myxoma_virus R-HSA-69610 p53-Independent DNA Damage Response 51/1217 52/10654 1.598629269536924e-47 4.190449489509554e-46 2.452544344082403e-46 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Myxoma_virus R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 51/1217 52/10654 1.598629269536924e-47 4.190449489509554e-46 2.452544344082403e-46 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Myxoma_virus R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 51/1217 52/10654 1.598629269536924e-47 4.190449489509554e-46 2.452544344082403e-46 5718/5689/1019/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/595/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Myxoma_virus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 71/1217 95/10654 2.588385772388866e-47 6.643523482464756e-46 3.888254943171872e-46 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/6147/6217/6230/6222/6176/6152/6136/6125/6224/6146/6141/26986/6202/6232/6169/6160/6164/4686/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6142/6204/6228/23521/140801/6156/6143/6181/6124/6207/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/22916/6208/6157/6137/6122/6133 71 Myxoma_virus R-HSA-9604323 Negative regulation of NOTCH4 signaling 52/1217 54/10654 4.3164675502802374e-47 1.0852832697847455e-45 6.351837318887139e-46 8454/5718/5689/5684/5720/5682/5700/5707/207/5690/5717/9491/6500/5706/5705/10197/7534/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/4855/55294/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 52 Myxoma_virus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 53/1217 56/10654 8.198522812236095e-47 2.020116020934974e-45 1.1823132897645737e-45 5718/3303/5689/5684/5720/5682/5700/122706/5707/5690/3184/5717/9491/23198/26986/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/3304/3312/5693/5721/5696/5691/7314 53 Myxoma_virus R-HSA-69563 p53-Dependent G1 DNA Damage Response 58/1217 66/10654 1.5243310445719786e-46 3.6027210697747015e-45 2.1085645358814685e-45 5718/1017/5689/9134/5684/5720/5682/5700/122706/5707/5690/5717/1027/9491/23198/898/11200/143471/5706/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/8900/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314/4193 58 Myxoma_virus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 58/1217 66/10654 1.5243310445719786e-46 3.6027210697747015e-45 2.1085645358814685e-45 5718/1017/5689/9134/5684/5720/5682/5700/122706/5707/5690/5717/1027/9491/23198/898/11200/143471/5706/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/8900/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314/4193 58 Myxoma_virus R-HSA-5610780 Degradation of GLI1 by the proteasome 55/1217 60/10654 1.5498718887829478e-46 3.6027210697747015e-45 2.1085645358814685e-45 8454/5718/5689/8945/5684/5720/2735/5682/5700/122706/5707/51684/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/83737/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 55 Myxoma_virus R-HSA-453279 Mitotic G1-G1/S phases 89/1217 149/10654 2.5001735303808584e-46 5.704099610054106e-45 3.338438339787306e-45 8454/5718/1017/6118/5689/26271/894/9134/1019/5684/5720/5682/7027/5700/5707/207/5690/5717/1027/9491/6500/898/5706/5705/10197/5934/7316/10213/5709/1869/891/1875/993/5695/890/983/1026/5714/5111/6714/4609/9861/5715/5519/4998/6119/5711/5701/5688/5687/4067/3717/6502/5685/5683/5698/5708/10000/5692/5686/990/5713/1021/1874/595/5699/5710/81620/5702/8900/896/5719/208/5704/6233/5716/7311/5518/6117/5694/1163/5693/5721/5696/5691/1028/7314/5515/5516 89 Myxoma_virus R-HSA-9020702 Interleukin-1 signaling 73/1217 103/10654 6.5897839975846216e-46 1.476111615458955e-44 8.639238350900414e-45 8454/3557/1147/5718/5689/8945/1326/5684/351/5720/4790/5682/5700/122706/5707/5690/3553/8878/5717/9491/23198/6500/143471/5706/5705/10197/8517/4615/7316/10213/5709/9978/5695/79155/7335/5970/4792/4793/5714/9861/5715/5711/3552/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/6288/5702/5719/3654/5704/6233/5716/7311/7334/5694/3551/5693/5721/5696/5691/4791/7314 73 Myxoma_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 65/1217 83/10654 1.179703467009783e-45 2.5953476274215225e-44 1.5189790881610928e-44 8454/1147/5718/5689/8945/5684/5720/4790/5966/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/8517/7316/10213/5709/5695/5970/4792/4793/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5478/5719/5704/6233/5716/7311/4794/5694/3265/3551/801/5693/5721/5696/5691/7314/805 65 Myxoma_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 72/1217 101/10654 1.4185716797746038e-45 3.066105806109319e-44 1.7944997241839405e-44 8454/1147/5718/5689/8945/5684/5720/4790/5682/5700/122706/7321/5707/5690/3553/9039/5717/9491/23198/6500/143471/5706/5705/10197/8517/7316/10213/5709/5695/9020/7335/5970/4792/5714/6714/9861/7322/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5971/7334/5694/3551/801/5693/5721/5696/997/5691/4791/7314/805 72 Myxoma_virus R-HSA-180534 Vpu mediated degradation of CD4 50/1217 52/10654 3.30430817112486e-45 7.018806322113496e-44 4.107896728167929e-44 5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Myxoma_virus R-HSA-69206 G1/S Transition 82/1217 131/10654 5.460702868537647e-45 1.1402688023793868e-43 6.673651141745385e-44 8454/5718/1017/6118/5689/26271/9134/1019/5684/5720/5682/7027/5700/5707/207/5690/5717/1027/9491/6500/898/5706/5705/10197/5934/7316/10213/5709/1869/891/1875/993/5695/890/983/1026/5714/5111/4609/9861/5715/5519/4998/6119/5711/5701/5688/5687/6502/5685/5683/5698/5708/10000/5692/5686/990/5713/1874/595/5699/5710/81620/5702/8900/5719/208/5704/6233/5716/7311/5518/6117/5694/1163/5693/5721/5696/5691/7314/5515/5516 82 Myxoma_virus R-HSA-2871837 FCERI mediated NF-kB activation 64/1217 82/10654 8.475755827090411e-45 1.740355196495898e-43 1.0185776739573565e-43 8454/1147/5718/5689/8945/5684/5720/4790/5682/5700/122706/7321/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/8517/7316/10213/5709/5695/7335/5970/4792/5714/9861/7322/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/7334/5694/3551/5693/5721/5696/997/5691/7314 64 Myxoma_virus R-HSA-2408557 Selenocysteine synthesis 68/1217 93/10654 2.7692490506358615e-44 5.5027658554570665e-43 3.2206037346104674e-43 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/6147/6217/6230/6222/6176/6152/6136/6125/6224/6146/6141/6202/6232/6169/6160/6164/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6142/6204/6228/23521/140801/6156/6143/6181/6124/6207/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133 68 Myxoma_virus R-HSA-72764 Eukaryotic Translation Termination 68/1217 93/10654 2.7692490506358615e-44 5.5027658554570665e-43 3.2206037346104674e-43 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/6147/6217/6230/6222/6176/6152/6136/6125/6224/6146/6141/6202/6232/6169/6160/6164/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6142/6204/6228/23521/140801/6156/6143/6181/6124/6207/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133 68 Myxoma_virus R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 48/1217 50/10654 2.514223904429552e-43 4.916704524217791e-42 2.877599623281943e-42 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 48 Myxoma_virus R-HSA-927802 Nonsense-Mediated Decay (NMD) 75/1217 115/10654 4.323103568143181e-43 8.193943993772922e-42 4.795669545227659e-42 10921/6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/6147/6217/6230/6222/6176/6152/6136/6125/6224/6146/6141/26986/6202/6232/6169/6160/6164/4686/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6142/6204/6228/23521/140801/6156/6143/6181/6124/6207/6233/7311/6223/25873/5518/3921/6188/6189/9775/6135/6201/6161/9045/6187/6168/22916/6208/6157/6137/6122/6133/5515 75 Myxoma_virus R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 75/1217 115/10654 4.323103568143181e-43 8.193943993772922e-42 4.795669545227659e-42 10921/6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/6147/6217/6230/6222/6176/6152/6136/6125/6224/6146/6141/26986/6202/6232/6169/6160/6164/4686/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6142/6204/6228/23521/140801/6156/6143/6181/6124/6207/6233/7311/6223/25873/5518/3921/6188/6189/9775/6135/6201/6161/9045/6187/6168/22916/6208/6157/6137/6122/6133/5515 75 Myxoma_virus R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 49/1217 52/10654 4.460171638072885e-43 8.233031078559335e-42 4.818546043073432e-42 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 49 Myxoma_virus R-HSA-5632684 Hedgehog 'on' state 64/1217 85/10654 4.477378914476262e-43 8.233031078559335e-42 4.818546043073432e-42 57154/5718/5689/5684/5720/2735/339745/5682/5700/122706/5707/1452/51684/5690/5717/9491/23198/409/79577/143471/5706/5705/10197/64750/8452/2737/7316/10213/5709/9978/5695/5727/5714/9861/5715/2736/8405/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/408/5699/5710/5702/83737/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 64 Myxoma_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 59/1217 73/10654 5.4256782080094014e-43 9.830052282746445e-42 5.753234632331951e-42 8454/57154/5718/5689/5684/5720/5682/5700/122706/5707/10273/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/11059/5714/6772/2099/9861/5715/5711/2932/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/55294/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 59 Myxoma_virus R-HSA-180585 Vif-mediated degradation of APOBEC3G 50/1217 54/10654 6.271753613184261e-43 1.1198261523830449e-41 6.554006445509107e-42 5718/5689/5684/8065/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Myxoma_virus R-HSA-8878159 Transcriptional regulation by RUNX3 68/1217 96/10654 8.596506170090848e-43 1.5129850859359893e-41 8.85504770904095e-42 57154/5718/5689/5684/5720/5682/1499/2648/5700/5707/5690/55534/3280/5717/9491/84441/5706/5705/10197/10046/64750/7316/10213/5709/5695/1026/5714/6714/6934/4609/9861/5715/22938/8850/5711/5701/5688/1387/5687/4088/5685/5683/5698/5708/5692/5686/5713/2033/595/5699/5710/5702/7157/5719/9794/5704/6233/5716/7311/5694/3516/4851/5693/5721/5696/5691/7314/4193 68 Myxoma_virus R-HSA-68949 Orc1 removal from chromatin 58/1217 71/10654 8.728389358916627e-43 1.514559956364125e-41 8.86426495308805e-42 8454/5718/1017/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/890/5714/9861/5715/4998/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/990/5713/5699/5710/81620/5702/8900/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 58 Myxoma_virus R-HSA-5610787 Hedgehog 'off' state 74/1217 113/10654 1.0224023635378973e-42 1.7494440442759574e-41 1.0238971038354675e-41 8454/5718/5689/8945/5684/5720/2735/5682/5700/122706/5707/1452/51684/5690/10382/5717/9491/23198/6500/112/7277/143471/114/5706/5705/10197/108/113/2737/7316/10213/5709/9978/5695/5727/111/107/5714/9861/5715/2736/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/81027/83737/5719/5704/6233/5716/7311/10383/84790/196883/115/5694/5693/5721/5696/109/5691/7314 74 Myxoma_virus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 60/1217 77/10654 5.5975779678357474e-42 9.446871310100878e-41 5.528970307090825e-41 5718/5689/5684/5720/5682/5700/122706/5707/5690/10382/5717/9491/23198/7277/143471/5706/5705/10197/7316/10213/5709/891/5695/983/1026/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/3320/5692/5686/5713/5699/5710/5702/81027/7157/5719/5704/6233/3326/5716/7311/10383/5347/84790/5694/5693/5721/5696/5691/7314 60 Myxoma_virus R-HSA-4641257 Degradation of AXIN 50/1217 55/10654 6.154434374583838e-42 1.0087246220599493e-40 5.903762526581214e-41 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/64750/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/8312/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Myxoma_virus R-HSA-8941858 Regulation of RUNX3 expression and activity 50/1217 55/10654 6.154434374583838e-42 1.0087246220599493e-40 5.903762526581214e-41 57154/5718/5689/5684/5720/5682/5700/5707/5690/5717/9491/5706/5705/10197/64750/7316/10213/5709/5695/5714/6714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/2033/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314/4193 50 Myxoma_virus R-HSA-4641258 Degradation of DVL 51/1217 57/10654 6.304528887874683e-42 1.0087246220599493e-40 5.903762526581214e-41 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/8452/7316/10213/5709/9978/5695/5714/59349/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Myxoma_virus R-HSA-69541 Stabilization of p53 51/1217 57/10654 6.304528887874683e-42 1.0087246220599493e-40 5.903762526581214e-41 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314/4193 51 Myxoma_virus R-HSA-8878166 Transcriptional regulation by RUNX2 76/1217 121/10654 6.608318498671588e-42 1.043775434661974e-40 6.108904415101265e-41 8454/57154/5718/5689/1019/5684/5720/5682/5700/122706/5707/10273/207/5690/5594/3280/5717/9491/23198/6500/10013/143471/5706/5705/10197/2737/7316/10213/5709/9978/891/5695/11059/983/1026/5714/6772/6714/2099/9861/5715/2736/5711/2932/5701/5688/5687/6502/4322/5685/5683/5698/5708/10000/5692/5686/5713/595/55294/5699/5710/5702/5719/208/5704/6233/5716/7311/10432/5694/5693/5721/5696/5691/7314/5595 76 Myxoma_virus R-HSA-446652 Interleukin-1 family signaling 82/1217 140/10654 8.151468741752161e-42 1.271216391118818e-40 7.440048085410035e-41 8454/3557/1147/5718/834/5689/8945/1326/5684/351/5720/4790/5682/90865/5700/122706/5707/29110/5690/3553/8878/5717/9491/23198/6500/143471/5706/5705/10197/8517/4615/7316/3565/10213/5709/9978/5695/79155/6774/7335/5970/4792/4793/5714/3606/9861/5715/5711/3552/5701/5688/5687/23291/4088/5685/5683/5698/5708/5692/5686/5713/5699/5710/6288/5702/5719/3654/5704/6233/5716/7311/5599/7334/5694/3551/5693/5721/5696/5691/4791/7314/3596 82 Myxoma_virus R-HSA-72689 Formation of a pool of free 40S subunits 69/1217 101/10654 9.483514506628464e-42 1.4604612340207835e-40 8.547641364526973e-41 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/6147/6217/6230/6222/6176/6152/6136/6125/6224/6146/6141/6202/6232/6169/6160/6164/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6142/6204/6228/23521/140801/6156/6143/6181/6124/6207/6233/7311/6223/25873/51386/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133 69 Myxoma_virus R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 51/1217 59/10654 3.066085763244384e-40 4.6634785929840506e-39 2.7293940842396406e-39 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/4998/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/990/5713/5699/5710/81620/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Myxoma_virus R-HSA-169911 Regulation of Apoptosis 48/1217 53/10654 4.1804117263870915e-40 6.280813715742556e-39 3.6759718004815896e-39 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 48 Myxoma_virus R-HSA-5358351 Signaling by Hedgehog 83/1217 149/10654 5.2561734542007275e-40 7.801934572982285e-39 4.566238194201013e-39 8454/57154/5718/5689/8945/5684/5720/2735/339745/5682/5700/122706/5707/1452/51684/5690/10382/5717/9491/23198/6500/409/79577/112/7277/143471/114/5706/5705/10197/108/64750/113/8452/2737/7316/10213/5709/9978/5695/5727/111/107/5714/7415/9861/5715/2736/8405/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/408/5699/5710/5702/81027/83737/5719/5704/6233/5716/7311/10383/84790/196883/115/5694/5693/5721/5696/109/5691/7314 83 Myxoma_virus R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 71/1217 111/10654 5.492147545397132e-40 8.055149733249126e-39 4.7144374293195934e-39 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/6147/6217/6230/6222/6176/6152/6136/6125/6224/6146/6141/26986/6202/6232/6169/6160/6164/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6142/6204/6228/23521/140801/6156/6143/1973/6181/6124/6207/6233/7311/6223/25873/51386/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133 71 Myxoma_virus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 54/1217 66/10654 5.7301170665854404e-40 8.305299089450897e-39 4.8608423413139654e-39 5718/5689/5684/5720/5682/5700/122706/7321/5707/5690/5717/9491/23198/143471/5706/5705/10197/7323/7316/10213/5709/9978/5695/5714/9861/7322/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/7428/5702/8453/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 54 Myxoma_virus R-HSA-8948751 Regulation of PTEN stability and activity 55/1217 69/10654 1.5728274975162722e-39 2.253166833651218e-38 1.3187109373300446e-38 5718/5689/5684/5720/5682/5700/122706/5707/10273/207/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/4734/5714/11060/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/10000/5692/5686/5713/5699/5710/5702/5719/208/5704/6233/5716/7311/5694/5693/5721/5696/23608/5691/7314 55 Myxoma_virus R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 49/1217 56/10654 2.963736385389511e-39 4.1969232491952616e-38 2.4563332413694075e-38 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 49 Myxoma_virus R-HSA-1234174 Cellular response to hypoxia 57/1217 75/10654 7.418108497520348e-39 1.0385351896528487e-37 6.078234833494544e-38 5718/5689/5684/5720/5682/5700/122706/7321/5707/7422/5690/5717/9491/23198/143471/5706/5705/10197/7323/7316/10213/5709/9978/5695/5714/9861/7322/5715/5711/5701/5688/1387/5687/5685/5683/5698/5708/5692/5686/5713/2033/5699/5710/7428/5702/8453/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 57 Myxoma_virus R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 70/1217 112/10654 1.860654181525639e-38 2.5756471366736936e-37 1.5074489820757692e-37 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/6147/6217/6230/6222/6176/6152/6136/6125/6224/6146/6141/6202/6232/6169/6160/6164/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6142/6204/6228/23521/140801/6156/6143/1973/6181/6124/6207/6233/7311/6223/25873/51386/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133 70 Myxoma_virus R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 69/1217 112/10654 2.486440573991085e-37 3.403660874618907e-36 1.9920605768232668e-36 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/6147/6217/6230/6222/6176/6152/6136/6125/6727/6224/6146/6141/6202/6232/6169/6160/6164/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6142/6204/6228/23521/140801/6156/6143/6181/6124/6207/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133 69 Myxoma_virus R-HSA-5658442 Regulation of RAS by GAPs 53/1217 68/10654 3.337673879612387e-37 4.518696944706001e-36 2.6446577299415678e-36 5718/5689/5684/5720/5682/153090/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/8452/7316/10213/5709/9978/5695/84078/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/3265/5693/5721/5696/5691/7314 53 Myxoma_virus R-HSA-5678895 Defective CFTR causes cystic fibrosis 50/1217 61/10654 3.727583550299989e-37 4.991720580401725e-36 2.9215042699719596e-36 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Myxoma_virus R-HSA-72613 Eukaryotic Translation Initiation 71/1217 119/10654 4.611809786613049e-37 6.044414528837529e-36 3.5376144499775356e-36 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/6147/6217/6230/6222/6176/6152/6136/6125/6224/6146/6141/26986/6202/6232/6169/6160/6164/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6142/6204/6228/23521/140801/6156/6143/1973/6181/6124/6207/6233/7311/6223/25873/51386/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133 71 Myxoma_virus R-HSA-72737 Cap-dependent Translation Initiation 71/1217 119/10654 4.611809786613049e-37 6.044414528837529e-36 3.5376144499775356e-36 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/6147/6217/6230/6222/6176/6152/6136/6125/6224/6146/6141/26986/6202/6232/6169/6160/6164/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6142/6204/6228/23521/140801/6156/6143/1973/6181/6124/6207/6233/7311/6223/25873/51386/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133 71 Myxoma_virus R-HSA-5387390 Hh mutants abrogate ligand secretion 49/1217 59/10654 5.69900065436131e-37 7.390704006498036e-36 4.3255572833656486e-36 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 49 Myxoma_virus R-HSA-2408522 Selenoamino acid metabolism 70/1217 118/10654 2.530852147803862e-36 3.2479269230149565e-35 1.9009141680325063e-35 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/6147/6217/191/6230/9255/6222/6176/6152/6136/6125/6224/6146/6141/6202/6232/6169/6160/6164/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6142/6204/6228/23521/140801/6156/6143/6181/6124/6207/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6122/6133 70 Myxoma_virus R-HSA-5621481 C-type lectin receptors (CLRs) 77/1217 142/10654 4.683927249197962e-36 5.949070485579267e-35 3.481812442431475e-35 8454/1147/5718/5689/8945/4586/5684/5720/4790/5682/5700/122706/7321/5707/5690/3553/9039/5717/9491/23198/6500/143471/5706/5705/10197/8517/7316/10213/5709/5695/9020/7335/5970/4792/5714/6714/9861/7322/5715/5711/5701/5688/1387/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/2033/5699/5710/5702/9040/5719/5704/6233/5716/7311/5971/7334/5694/3265/3551/801/5693/5721/5696/997/5691/4791/7314/805 77 Myxoma_virus R-HSA-202424 Downstream TCR signaling 63/1217 98/10654 8.850397818999184e-36 1.1126214401027545e-34 6.511839426438714e-35 8454/1147/5718/5689/8945/5684/5720/4790/5682/5700/122706/7321/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/8517/7316/10213/5709/5695/7335/5970/4792/5714/9861/7322/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/7334/5694/3551/5693/5721/5696/997/5691/7314 63 Myxoma_virus R-HSA-68867 Assembly of the pre-replicative complex 52/1217 68/10654 8.969501378890641e-36 1.1162046160397242e-34 6.532810680000095e-35 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/1869/5695/5714/9861/5715/4998/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/990/5713/5699/5710/81620/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 52 Myxoma_virus R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 44/1217 50/10654 1.3873211331506918e-35 1.7091796360416523e-34 1.0003315539033937e-34 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/5694/5693/5721/5696/5691 44 Myxoma_virus R-HSA-168255 Influenza Life Cycle 77/1217 144/10654 1.739766460802688e-35 2.1221705739692195e-34 1.2420427573213563e-34 6158/3303/6138/6144/6203/5903/6227/9349/4736/2926/6206/6194/6234/6191/6128/51121/6132/6147/6217/5430/6230/6222/6176/6152/6136/6125/6224/6146/6141/6202/6232/6169/6160/6164/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6142/6204/6228/23521/3320/140801/6156/6143/6181/6124/6207/3836/6233/7311/6223/25873/1213/3921/6188/6189/6135/6201/6161/3304/9045/6187/6168/6208/6157/6137/8480/6122/6133 77 Myxoma_virus R-HSA-380108 Chemokine receptors bind chemokines 48/1217 59/10654 2.0536214356949532e-35 2.480452557623708e-34 1.4517344514458648e-34 729230/57007/10803/10663/7852/3579/6351/6374/1237/1230/2919/3577/3576/6360/5196/2920/2826/2921/1236/6352/6376/6348/6354/3627/6346/6364/10563/6370/58191/1524/643/10850/2829/1233/6372/6366/5473/4283/6363/6373/2833/6347/6357/6356/56477/1232/1234/6387 48 Myxoma_virus R-HSA-168254 Influenza Infection 80/1217 155/10654 2.2995652722372678e-35 2.750547976112926e-34 1.6098131951788745e-34 6158/3303/6138/6144/3838/6203/5903/6227/9349/4736/2926/6206/6194/6234/6191/6128/51121/6132/6147/6217/5430/6230/6222/6176/6152/6136/8106/6125/6224/6146/6141/6202/6232/6169/6160/6164/6155/6175/293/6218/6209/6193/6210/6229/11224/6205/6165/6142/6204/6228/23521/3320/140801/6156/6143/6181/6124/6207/3836/6233/7311/6223/25873/1213/3921/6188/6189/6135/6201/6161/3304/9045/6187/6168/6208/6157/6137/8480/6122/6133 80 Myxoma_virus R-HSA-4608870 Asymmetric localization of PCP proteins 50/1217 64/10654 3.028662084234064e-35 3.5877996997849683e-34 2.0998315057695687e-34 57154/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/64750/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Myxoma_virus R-HSA-3858494 Beta-catenin independent WNT signaling 77/1217 146/10654 6.260953210480362e-35 7.346185100296957e-34 4.299501703437642e-34 2788/57154/5718/5689/27161/5684/5720/54331/5682/1499/59345/51701/5700/122706/5707/5690/5717/9491/23198/10681/409/51764/94235/143471/5706/5705/10197/64750/7316/10213/5709/5695/55970/2792/5714/6934/9861/5715/5711/5701/5688/2793/5687/5685/5683/5698/5708/5880/5692/5686/5713/2785/5699/2783/2784/5710/2782/5702/2786/5719/23112/5704/6233/5716/7311/1213/5694/801/5693/5721/2791/5696/5691/7314/2790/805/2787 77 Myxoma_virus R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 44/1217 51/10654 9.014793408912435e-35 1.0477571207339736e-33 6.1322080289027e-34 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/5694/5693/5721/5696/5691 44 Myxoma_virus R-HSA-168273 Influenza Viral RNA Transcription and Replication 73/1217 134/10654 2.076239497657063e-34 2.3905860384238332e-33 1.399138274368016e-33 6158/6138/6144/6203/5903/6227/9349/4736/2926/6206/6194/6234/6191/6128/51121/6132/6147/6217/5430/6230/6222/6176/6152/6136/6125/6224/6146/6141/6202/6232/6169/6160/6164/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6142/6204/6228/23521/3320/140801/6156/6143/6181/6124/6207/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/8480/6122/6133 73 Myxoma_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 66/1217 112/10654 4.722418076491328e-34 5.387054694664181e-33 3.152881464324132e-33 8454/1147/5718/5689/8945/5684/5720/4790/5966/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/8517/7316/10213/5709/5695/5970/4792/4793/5714/9861/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5478/5719/5704/6233/5716/7311/4794/5694/3265/3551/801/5693/5721/5696/5691/7314/805 66 Myxoma_virus R-HSA-1236974 ER-Phagosome pathway 56/1217 83/10654 1.292258039910532e-33 1.4606072524493352e-32 8.548495966573775e-33 1147/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10333/10197/7099/8517/4615/7316/10213/5709/5695/7096/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/7097/3551/5693/5721/5696/5691/7314 56 Myxoma_virus R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 86/1217 185/10654 1.646438257084739e-33 1.8440108479349075e-32 1.0792442163665515e-32 6158/5393/6138/6144/6203/6227/9349/4736/6206/6194/6234/22803/6191/6128/51121/6132/6147/23404/6217/6230/6222/6176/6152/6136/6125/6224/6146/6141/6202/6232/6169/6160/6164/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6142/6204/6228/23521/55131/140801/6156/117246/5822/6143/51013/6181/6124/6207/10969/6233/7311/6223/25873/26168/11340/3921/6188/6189/51010/26354/6135/6201/6161/56915/9045/6187/4691/23016/6168/6208/54512/6157/6137/118460/6122/6133/22894 86 Myxoma_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 72/1217 134/10654 2.008785488037792e-33 2.2295709200563601e-32 1.3049009571416668e-32 8454/1147/5718/5689/3725/8945/5684/5720/4790/5682/5700/122706/7321/5707/5690/5594/5717/9491/23198/6500/143471/5706/5705/10197/8517/7316/10213/5709/5695/7335/5970/4792/5714/9861/7322/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/2353/7311/5599/7334/5694/3265/3551/801/5693/5721/5696/997/5691/7314/5595/805 72 Myxoma_virus R-HSA-2467813 Separation of Sister Chromatids 87/1217 190/10654 2.8775886769981343e-33 3.1653475446979477e-32 1.8525829358493628e-32 5718/5689/5684/5903/5720/11065/54908/5682/246184/5525/5700/122706/7321/5707/991/5526/8697/5690/10382/5717/9491/23198/7277/143471/5706/5705/10197/6232/8881/5528/7316/10213/5709/5695/5501/8655/5714/51433/9861/5715/5519/5711/5701/5688/1062/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5529/5710/5702/81027/51529/7324/5719/64682/29945/10393/9232/5704/6233/5527/51434/5716/7311/5518/25906/10383/5347/84790/29882/5694/5693/5721/5696/5691/7314/996/5515/5516 87 Myxoma_virus R-HSA-5358346 Hedgehog ligand biogenesis 49/1217 65/10654 2.9611716617588446e-33 3.2284632630857486e-32 1.8895226719187782e-32 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 49 Myxoma_virus R-HSA-8868773 rRNA processing in the nucleus and cytosol 88/1217 195/10654 4.85586507908506e-33 5.247741910028767e-32 3.071345871812804e-32 6158/5393/6138/6144/6203/6227/9349/4736/6206/6194/6234/22803/6191/6128/51121/6132/6147/23404/6217/55226/6230/6222/6176/6152/6136/6125/4839/6224/6146/6141/6202/6232/6169/6160/6164/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6142/6204/6228/23521/55131/140801/6156/117246/5822/6143/51013/6181/6124/6207/10969/6233/7311/6223/25873/26168/11340/3921/6188/6189/51010/26354/6135/6201/6161/56915/9045/6187/4691/23016/6168/6208/54512/6157/6137/118460/6122/6133/22894 88 Myxoma_virus R-HSA-69002 DNA Replication Pre-Initiation 56/1217 85/10654 9.045462953347599e-33 9.690443790021079e-32 5.671525970748838e-32 5718/1017/6118/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/1869/5695/5714/9861/5715/4998/6119/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/990/5713/5699/5710/81620/5702/5719/5704/6233/5716/7311/6117/5694/5693/5721/5696/5691/7314 56 Myxoma_virus R-HSA-5663202 Diseases of signal transduction 128/1217 377/10654 2.59933951395439e-32 2.760677828613628e-31 1.6157418938827198e-31 8454/1147/5718/5689/5684/5720/3667/8087/142678/5682/1499/2648/5525/892/5700/139285/122706/5707/5430/5526/207/1452/5690/55534/5594/3280/9530/27121/5717/1027/9491/23198/6500/409/3082/84441/10533/10013/143471/5706/2064/5705/10197/10046/5528/4686/7316/10213/5709/9978/1950/5695/8315/6774/1026/1024/5714/6772/6714/2099/6934/4609/7415/9861/5715/22938/5519/8850/5711/2932/5701/5688/1387/5687/3717/4088/2247/5685/5683/5698/5708/5880/10000/3320/5692/5686/5713/324/2335/2033/408/55294/5699/8312/5529/5710/5702/4087/5719/208/9794/5704/6233/5527/5716/7048/7311/5518/1956/60/5694/3265/3516/801/4851/22916/5693/5721/5696/5691/940/7314/253260/5595/4193/805/5515/5516 128 Myxoma_virus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 61/1217 102/10654 4.602912865602847e-32 4.846827906344195e-31 2.8367029356166895e-31 8454/7124/1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/8600/5690/9039/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/9020/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5971/958/5694/5693/5721/5696/5691/4791/7314 61 Myxoma_virus R-HSA-72312 rRNA processing 89/1217 205/10654 8.089168384859148e-32 8.445640211988535e-31 4.942979789142299e-31 6158/5393/6138/6144/6203/6227/9349/4736/6206/6194/6234/22803/6191/6128/51121/6132/6147/23404/6217/3028/55226/6230/6222/6176/6152/6136/6125/4839/6224/6146/6141/6202/6232/6169/6160/6164/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6142/6204/6228/23521/55131/140801/6156/117246/5822/6143/51013/6181/6124/6207/10969/6233/7311/6223/25873/26168/11340/3921/6188/6189/51010/26354/6135/6201/6161/56915/9045/6187/4691/23016/6168/6208/54512/6157/6137/118460/6122/6133/22894 89 Myxoma_virus R-HSA-2555396 Mitotic Metaphase and Anaphase 88/1217 202/10654 1.314742895518841e-31 1.3611455859489178e-30 7.966376677845257e-31 5718/5689/26271/5684/5903/5720/11065/54908/5682/246184/5525/5700/122706/7321/5707/991/5526/8697/5690/10382/5717/9491/23198/7277/143471/5706/5705/10197/6232/8881/5528/7316/10213/5709/5695/5501/8655/5714/51433/9861/5715/5519/5711/5701/5688/1062/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5529/5710/5702/81027/51529/7324/5719/64682/29945/10393/9232/5704/6233/5527/51434/5716/7311/5518/25906/10383/5347/84790/29882/5694/5693/5721/5696/5691/7314/996/5515/5516 88 Myxoma_virus R-HSA-68882 Mitotic Anaphase 87/1217 201/10654 5.310098679741754e-31 5.451701311201535e-30 3.190717189143072e-30 5718/5689/5684/5903/5720/11065/54908/5682/246184/5525/5700/122706/7321/5707/991/5526/8697/5690/10382/5717/9491/23198/7277/143471/5706/5705/10197/6232/8881/5528/7316/10213/5709/5695/5501/8655/5714/51433/9861/5715/5519/5711/5701/5688/1062/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5529/5710/5702/81027/51529/7324/5719/64682/29945/10393/9232/5704/6233/5527/51434/5716/7311/5518/25906/10383/5347/84790/29882/5694/5693/5721/5696/5691/7314/996/5515/5516 87 Myxoma_virus R-HSA-420499 Class C/3 (Metabotropic glutamate/pheromone receptors) 35/1217 38/10654 4.064944656060031e-30 4.138852740715668e-29 2.4223463152684835e-29 2913/50833/338398/5726/2916/259293/259287/2550/50836/50832/846/2918/259294/259290/2912/259295/9568/54429/80834/259292/50834/259285/50838/2914/2917/50831/50839/83756/80835/259296/259289/50835/50840/259286/50837 35 Myxoma_virus R-HSA-5687128 MAPK6/MAPK4 signaling 55/1217 89/10654 4.5760439455202885e-30 4.621054213836882e-29 2.7045643681461584e-29 5718/5689/27161/3725/5684/5720/5682/5700/10642/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/983/5714/4609/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/896/5719/23112/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 55 Myxoma_virus R-HSA-202403 TCR signaling 64/1217 119/10654 7.47440277848909e-30 7.486556278941917e-29 4.381656742203703e-29 8454/1147/5718/5689/8945/5684/5720/4790/5682/5700/122706/7321/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/8517/7316/10213/5709/5695/7335/5970/4792/5714/9861/7322/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/7408/5699/5710/5702/5719/5704/6233/5716/7311/7334/5694/3551/5693/5721/5696/997/5691/7314 64 Myxoma_virus R-HSA-351202 Metabolism of polyamines 44/1217 59/10654 1.2435486915302835e-29 1.2355257967462172e-28 7.231161746165062e-29 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/5694/5693/5721/5696/5691 44 Myxoma_virus R-HSA-453274 Mitotic G2-G2/M phases 84/1217 198/10654 3.349241240486527e-29 3.3010121666235208e-28 1.931983368196439e-28 8454/5718/1017/5689/8945/5684/994/5720/5682/7531/4659/5700/122706/5707/203068/5690/10382/5717/9491/23198/6500/7277/143471/5706/5705/10197/7316/10213/5709/9978/1869/891/993/5695/890/8655/983/1026/6790/5714/10121/9861/5715/5519/5711/5701/5688/5687/23291/5685/5683/5698/5708/3320/5692/5686/5713/2033/5699/5710/5702/81027/7157/8900/79866/5719/5704/6233/3326/5716/7311/23194/5518/10383/5347/84790/5694/5693/5721/5696/5691/7314/5515/5516 84 Myxoma_virus R-HSA-9006925 Intracellular signaling by second messengers 108/1217 305/10654 4.2309630719508436e-29 4.136941670351936e-28 2.421227823129764e-28 1147/5718/5689/27161/3725/3838/5684/5720/3667/5682/90865/5525/5700/122706/5707/2146/5526/10273/207/5690/5594/5717/1027/9491/23198/3082/112/143471/114/5706/2064/5705/10197/108/4615/113/5528/7316/10213/5709/1950/5695/111/107/1026/4734/5714/6714/2099/11060/9861/5715/5519/5711/1958/2932/5701/5688/5687/2247/5685/5683/5698/5708/5880/10000/5692/5686/5713/5699/5529/5710/6615/3630/5702/7157/5719/3654/5371/23112/208/5704/6233/5527/5716/7311/5518/1956/8726/196883/115/5694/7874/801/5693/5721/5696/23608/109/5691/940/7314/253260/5595/4193/805/5515/5516 108 Myxoma_virus R-HSA-5619084 ABC transporter disorders 50/1217 77/10654 6.280432389406239e-29 6.092513939959439e-28 3.5657655919960833e-28 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Myxoma_virus R-HSA-69620 Cell Cycle Checkpoints 105/1217 293/10654 8.27027119355378e-29 7.960136023795512e-28 4.658828756237121e-28 5718/1017/6118/5689/9134/5684/5903/5720/11065/54908/5682/246184/5525/7531/5700/122706/7321/5707/991/5526/8697/5690/5717/1027/9491/23198/898/11200/143471/5706/5705/10197/7336/6232/7534/8881/5528/7316/10213/5709/891/993/5695/5501/890/8655/983/1026/5714/51433/9861/5715/5519/4998/6119/5711/5701/5688/1062/5687/5685/5683/5698/5708/5692/5686/990/5713/119504/5699/5529/5710/1111/5702/7157/8900/51529/7324/5719/64682/29945/10393/8924/5704/6233/5527/51434/5716/7311/5518/25906/5347/6117/29882/7334/5694/5693/5721/5696/5691/7314/996/4193/5515/5516 105 Myxoma_virus R-HSA-69275 G2/M Transition 83/1217 196/10654 8.510498490999227e-29 8.127855923186858e-28 4.7569901806074835e-28 8454/5718/1017/5689/8945/5684/994/5720/5682/7531/4659/5700/122706/5707/203068/5690/10382/5717/9491/23198/6500/7277/143471/5706/5705/10197/7316/10213/5709/9978/891/993/5695/890/8655/983/1026/6790/5714/10121/9861/5715/5519/5711/5701/5688/5687/23291/5685/5683/5698/5708/3320/5692/5686/5713/2033/5699/5710/5702/81027/7157/8900/79866/5719/5704/6233/3326/5716/7311/23194/5518/10383/5347/84790/5694/5693/5721/5696/5691/7314/5515/5516 83 Myxoma_virus R-HSA-71291 Metabolism of amino acids and derivatives 121/1217 372/10654 1.414166839087319e-28 1.3401950351965978e-27 7.843759390889179e-28 6158/5718/5689/6138/6144/38/6203/5684/6227/9349/4736/5720/6206/6194/6234/6191/6128/5682/51121/6132/6147/6217/5700/3028/122706/5707/191/6230/9255/6222/6176/6152/5690/6136/6125/5717/9491/23198/1737/6224/6146/6141/143471/6202/5706/5705/10197/6232/6169/6160/6164/6155/10213/5709/6175/6218/5695/5092/6209/5714/6193/6210/6229/11224/6205/6165/9861/5715/6142/5711/6204/5701/5688/6228/23521/5687/1152/5685/5683/5698/5708/5692/5686/5713/140801/6156/5699/6143/5710/6181/6124/5702/6207/3034/5719/5704/6233/5716/7311/6223/25873/3921/6188/6189/6135/5860/6201/6161/5694/9045/6187/6168/5693/6208/6157/5721/6137/5696/5691/6122/6133 121 Myxoma_virus R-HSA-2262752 Cellular responses to stress 141/1217 479/10654 3.7322138120483327e-28 3.509990394231715e-27 2.0542920540402638e-27 5718/1017/3303/6118/5689/3725/9134/1019/5684/5903/5720/11065/4790/5682/246184/7531/7027/1915/5700/122706/7321/5707/2146/7422/8697/5690/10382/5594/9530/3308/5717/1027/9491/23198/898/7295/7277/1051/10013/143471/5706/5705/79813/10197/3576/3313/8881/7001/7323/7316/10213/5709/9978/1869/5695/890/10935/3305/8655/6774/5970/1026/5714/9588/10121/7415/51433/9861/7322/5715/6119/5711/3552/1432/2932/5701/5688/1387/5687/3310/5685/5683/3309/5698/5708/3320/5692/5686/5713/2033/1021/119504/5699/5710/25842/3301/7428/5702/81027/7157/8453/8900/51529/7324/5719/64682/29945/10393/23112/5704/6233/51434/3326/5716/2353/51343/7311/25906/10383/84790/8726/6117/29882/5599/5600/5694/3304/3312/3456/5052/3569/5693/5721/5696/5691/8480/10919/7314/996/5595/4193 141 Myxoma_virus R-HSA-1236975 Antigen processing-Cross presentation 56/1217 99/10654 8.877821236423946e-28 8.285966487329017e-27 4.849527549402236e-27 1147/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10333/10197/7099/8517/4615/7316/10213/5709/5695/7096/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/7097/3551/5693/5721/5696/5691/7314 56 Myxoma_virus R-HSA-6807070 PTEN Regulation 67/1217 140/10654 2.9981457576011337e-27 2.777229754409471e-26 1.6254292393801161e-26 5718/5689/27161/3725/5684/5720/5682/5700/122706/5707/2146/10273/207/5690/5594/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/4734/5714/11060/9861/5715/5711/1958/5701/5688/5687/5685/5683/5698/5708/10000/5692/5686/5713/5699/5710/6615/5702/7157/5719/5371/23112/208/5704/6233/5716/7311/8726/5694/7874/5693/5721/5696/23608/5691/7314/5595 67 Myxoma_virus R-HSA-1257604 PIP3 activates AKT signaling 96/1217 264/10654 5.821790255317386e-27 5.352571339217178e-26 3.132699391117368e-26 1147/5718/5689/27161/3725/5684/5720/3667/5682/90865/5525/5700/122706/5707/2146/5526/10273/207/5690/5594/5717/1027/9491/23198/3082/143471/5706/2064/5705/10197/4615/5528/7316/10213/5709/1950/5695/1026/4734/5714/6714/2099/11060/9861/5715/5519/5711/1958/2932/5701/5688/5687/2247/5685/5683/5698/5708/5880/10000/5692/5686/5713/5699/5529/5710/6615/3630/5702/7157/5719/3654/5371/23112/208/5704/6233/5527/5716/7311/5518/1956/8726/5694/7874/5693/5721/5696/23608/5691/940/7314/253260/5595/4193/5515/5516 96 Myxoma_virus R-HSA-4086400 PCP/CE pathway 53/1217 92/10654 6.92668001312749e-27 6.32123687123931e-26 3.6996302604228697e-26 57154/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/409/143471/5706/5705/10197/64750/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5880/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/1213/5694/5693/5721/5696/5691/7314 53 Myxoma_virus R-HSA-8953897 Cellular responses to external stimuli 141/1217 493/10654 9.557168460880001e-27 8.657670252797177e-26 5.0670746096770905e-26 5718/1017/3303/6118/5689/3725/9134/1019/5684/5903/5720/11065/4790/5682/246184/7531/7027/1915/5700/122706/7321/5707/2146/7422/8697/5690/10382/5594/9530/3308/5717/1027/9491/23198/898/7295/7277/1051/10013/143471/5706/5705/79813/10197/3576/3313/8881/7001/7323/7316/10213/5709/9978/1869/5695/890/10935/3305/8655/6774/5970/1026/5714/9588/10121/7415/51433/9861/7322/5715/6119/5711/3552/1432/2932/5701/5688/1387/5687/3310/5685/5683/3309/5698/5708/3320/5692/5686/5713/2033/1021/119504/5699/5710/25842/3301/7428/5702/81027/7157/8453/8900/51529/7324/5719/64682/29945/10393/23112/5704/6233/51434/3326/5716/2353/51343/7311/25906/10383/84790/8726/6117/29882/5599/5600/5694/3304/3312/3456/5052/3569/5693/5721/5696/5691/8480/10919/7314/996/5595/4193 141 Myxoma_virus R-HSA-195721 Signaling by WNT 108/1217 331/10654 1.1006600488692193e-25 9.897906424867724e-25 5.792947625627471e-25 2788/8454/57154/5718/5689/27161/8945/5684/8295/5720/54331/6597/5682/1499/5525/59345/51701/5700/139285/122706/5707/5526/84133/207/1452/5690/27121/5717/9491/23198/6500/10681/409/79577/51764/94235/143471/5706/5705/10197/7534/64750/8452/5528/7316/10213/5709/9978/5695/55970/2792/5714/6934/4609/59349/9861/5715/5519/5711/2932/5701/5688/1387/2793/5687/5685/5683/5698/5708/5880/5692/5686/5713/324/2033/2785/5699/2783/2784/8312/5529/5710/2782/5702/2786/5719/23112/208/5704/6233/5527/5716/7311/5518/1213/5694/801/5693/5721/2791/5696/5691/7314/2790/805/5515/2787/5516 108 Myxoma_virus R-HSA-162909 Host Interactions of HIV factors 62/1217 129/10654 1.9943796394284884e-25 1.7804896491129696e-24 1.04206716476622e-24 5718/5689/8945/5684/5903/8065/5720/5682/5700/122706/5707/5690/5717/4869/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/293/5695/292/3055/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5478/5719/3836/5704/6233/5716/1025/7311/5694/5693/5721/5696/5691/8480/940/7314 62 Myxoma_virus R-HSA-157118 Signaling by NOTCH 86/1217 235/10654 1.8416848514733238e-24 1.632342256845421e-23 9.553609415064196e-24 8454/5718/5689/27161/3725/5684/5720/142678/5682/2648/892/7027/5700/5707/207/4904/5690/55534/3280/5717/9491/6500/409/84441/10013/5706/5705/10197/10046/7534/7316/10213/5709/9978/1950/1869/5695/1024/5714/6772/4609/11060/9861/5715/22938/8850/5711/5701/5688/1387/5687/4088/5685/5683/5698/5708/59/5692/5686/5713/2033/408/4855/595/55294/5699/5710/5702/7157/83737/5719/23112/9794/5704/6233/5716/7311/1956/5694/3516/4851/5693/5721/5696/5691/7314 86 Myxoma_virus R-HSA-109581 Apoptosis 73/1217 178/10654 2.0706913899342257e-24 1.822208423142119e-23 1.0664839113571013e-23 5718/5689/5684/5720/5682/1499/7531/7027/5700/122706/5707/207/5690/5594/5717/9491/23198/143471/5706/5705/10197/7099/7534/7316/10213/5709/1869/5695/8655/6774/5714/9861/5715/5711/5701/28988/5688/5687/999/598/5685/5683/5698/5708/10000/5692/5686/708/5713/324/5699/5710/5702/7157/5719/3836/208/5704/6233/6709/5716/7311/7161/1677/5599/7431/5694/5693/5721/5696/5691/7314/5595 73 Myxoma_virus R-HSA-5357801 Programmed Cell Death 73/1217 181/10654 7.010562225714482e-24 6.125540895092371e-23 3.585095277800986e-23 5718/5689/5684/5720/5682/1499/7531/7027/5700/122706/5707/207/5690/5594/5717/9491/23198/143471/5706/5705/10197/7099/7534/7316/10213/5709/1869/5695/8655/6774/5714/9861/5715/5711/5701/28988/5688/5687/999/598/5685/5683/5698/5708/10000/5692/5686/708/5713/324/5699/5710/5702/7157/5719/3836/208/5704/6233/6709/5716/7311/7161/1677/5599/7431/5694/5693/5721/5696/5691/7314/5595 73 Myxoma_virus R-HSA-5689603 UCH proteinases 52/1217 102/10654 4.916466980583325e-23 4.265554450759617e-22 2.496501024239865e-22 5718/5689/5684/5720/5682/5700/122706/5707/4738/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/123228/5716/7048/7311/60/5694/5693/5721/5696/5691/7314 52 Myxoma_virus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 23/1217 23/10654 1.7715992770128742e-22 1.5263009155803224e-21 8.932981264290163e-22 11065/246184/7321/991/8697/8881/7316/891/983/51433/119504/51529/7324/64682/29945/10393/6233/51434/7311/25906/29882/7314/996 23 Myxoma_virus R-HSA-5684996 MAPK1/MAPK3 signaling 86/1217 255/10654 1.0740331492031637e-21 9.188950276515955e-21 5.3780168655275374e-21 5718/5689/5684/6711/5720/1437/3667/5682/5525/153090/5700/122706/5707/5526/5690/5594/5717/9491/23198/409/3082/143471/5706/2064/5705/10197/8452/5528/7316/10213/5709/9978/1950/5695/8315/983/84078/5714/6714/9861/5715/5519/5711/5701/5688/3567/5687/3558/3717/2247/5685/5683/5698/5708/5692/5686/5713/2335/408/5699/5529/5710/5702/5719/5704/6233/5527/6709/5716/7311/5518/1956/60/5694/3265/801/3569/5693/5721/5696/5691/7314/5595/805/5515/5516 86 Myxoma_virus R-HSA-392170 ADP signalling through P2Y purinoceptor 12 22/1217 22/10654 1.576204478092124e-21 1.3392302875927562e-20 7.83811301265412e-21 2788/54331/59345/64805/2770/10681/51764/94235/55970/2792/346562/2793/2785/2783/2784/2782/2786/2771/2791/2773/2790/2787 22 Myxoma_virus R-HSA-5673001 RAF/MAP kinase cascade 84/1217 249/10654 3.1904586095964067e-21 2.6922226075498446e-20 1.575677107118629e-20 5718/5689/5684/6711/5720/1437/3667/5682/5525/153090/5700/122706/5707/5526/5690/5594/5717/9491/23198/409/3082/143471/5706/2064/5705/10197/8452/5528/7316/10213/5709/9978/1950/5695/8315/84078/5714/6714/9861/5715/5519/5711/5701/5688/3567/5687/3558/3717/2247/5685/5683/5698/5708/5692/5686/5713/2335/408/5699/5529/5710/5702/5719/5704/6233/5527/6709/5716/7311/5518/1956/60/5694/3265/801/5693/5721/5696/5691/7314/5595/805/5515/5516 84 Myxoma_virus R-HSA-382556 ABC-family proteins mediated transport 50/1217 103/10654 5.578301426312169e-21 4.6751478620521036e-20 2.736223757267337e-20 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Myxoma_virus R-HSA-9607240 FLT3 Signaling 87/1217 267/10654 8.352594569802153e-21 6.937091405787944e-20 4.060071439648618e-20 54106/5718/5689/5684/6711/5720/1437/3667/5682/5525/153090/5700/122706/5707/5526/5690/5594/5717/9491/23198/409/3082/143471/5706/2064/5705/10197/8452/5528/7316/10213/5709/9978/1950/5695/8315/3055/84078/5714/6714/9861/5715/5519/5711/5701/5688/3567/5687/3558/3717/2247/5685/5683/5698/5708/5692/5686/5713/2335/408/5699/5529/5710/5702/5719/208/5704/6233/5527/6709/5716/7311/5518/1956/60/5694/3265/801/5693/5721/5696/5691/7314/5595/805/5515/5516 87 Myxoma_virus R-HSA-201681 TCF dependent signaling in response to WNT 80/1217 233/10654 8.389826456675355e-21 6.937091405787944e-20 4.060071439648618e-20 5718/5689/8945/5684/8295/5720/6597/5682/1499/5525/5700/139285/122706/5707/5526/84133/207/1452/5690/27121/5717/9491/23198/79577/143471/5706/5705/10197/7534/64750/8452/5528/7316/10213/5709/9978/5695/5714/6934/4609/59349/9861/5715/5519/5711/2932/5701/5688/1387/5687/5685/5683/5698/5708/5692/5686/5713/324/2033/5699/8312/5529/5710/5702/5719/208/5704/6233/5527/5716/7311/5518/5694/5693/5721/5696/5691/7314/5515/5516 80 Myxoma_virus R-HSA-418597 G alpha (z) signalling events 33/1217 48/10654 1.07383174349649e-20 8.81973805325117e-20 5.1619280301410215e-20 2788/151/54331/59345/2770/10681/51764/112/94235/114/108/150/113/55970/111/107/2792/346562/152/2793/2785/2783/2784/2782/2786/2771/196883/115/2791/109/2773/2790/2787 33 Myxoma_virus R-HSA-5683057 MAPK family signaling cascades 92/1217 294/10654 1.4129079484217506e-20 1.1527831738116537e-19 6.746894002571622e-20 5718/5689/27161/3725/5684/6711/5720/1437/3667/5682/5525/153090/5700/10642/122706/5707/5526/5690/5594/5717/9491/23198/409/3082/143471/5706/2064/5705/10197/8452/5528/7316/10213/5709/9978/1950/5695/8315/983/84078/5714/6714/4609/9861/5715/5519/5711/5701/5688/3567/5687/3558/3717/2247/5685/5683/5698/5708/5692/5686/5713/2335/408/5699/5529/5710/5702/896/5719/23112/5704/6233/5527/6709/5716/7311/5518/1956/60/5694/3265/801/3569/5693/5721/5696/5691/7314/5595/805/5515/5516 92 Myxoma_virus R-HSA-9009391 Extra-nuclear estrogen signaling 42/1217 77/10654 2.573718399489681e-20 2.0860664922179518e-19 1.2209121216415733e-19 2788/54331/59345/2770/207/1903/5594/1027/10681/51764/94235/4318/4313/1950/55970/4314/2792/346562/6714/2099/2793/10000/3320/2785/595/2783/2784/2782/2786/2771/208/2353/1956/3276/3265/801/2791/2773/5595/2790/805/2787 42 Myxoma_virus R-HSA-69481 G2/M Checkpoints 65/1217 168/10654 3.081690156437312e-20 2.481465537732528e-19 1.4523273183072298e-19 5718/1017/6118/5689/5684/5720/5682/7531/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7336/7534/7316/10213/5709/891/993/5695/983/5714/9861/5715/4998/6119/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/990/5713/5699/5710/1111/5702/7157/5719/8924/5704/6233/5716/7311/6117/7334/5694/5693/5721/5696/5691/7314 65 Myxoma_virus R-HSA-392518 Signal amplification 26/1217 32/10654 1.1439692512387205e-19 9.151754009909764e-19 5.356247006825179e-19 2788/54331/59345/64805/2770/10681/51764/94235/2769/55970/2792/346562/6714/1432/2793/2785/2783/2784/2782/2786/2771/9630/2791/2773/2790/2787 26 Myxoma_virus R-HSA-5689880 Ub-specific processing proteases 75/1217 220/10654 2.3081346943377796e-19 1.8345948022091255e-18 1.073733287348984e-18 5718/5689/5684/8295/5720/5682/90865/2648/5700/122706/5707/991/8237/5690/9817/5717/9491/23198/409/6478/1080/143471/5706/5705/57695/55031/10197/8517/64750/7316/10213/5709/993/5695/890/4792/5714/4609/9861/5715/5711/5701/5688/5687/6502/4088/5685/5683/5698/5708/5692/5686/5713/408/5699/8312/5710/5702/7157/8900/4087/63891/5719/5704/6233/5716/7311/5694/7874/5693/5721/5696/5691/7314/4193 75 Myxoma_virus R-HSA-390466 Chaperonin-mediated protein folding 46/1217 95/10654 2.400746991436836e-19 1.89597454708345e-18 1.109657010212033e-18 2788/10694/26224/9134/54331/22803/59345/2770/8237/10575/10382/10681/898/51764/7277/94235/10517/10576/55970/6774/2792/26272/346562/2793/26270/2785/55294/2783/26190/2784/2782/81027/7157/2786/2771/6468/10383/60/54461/84790/26234/2791/84261/2773/2790/2787 46 Myxoma_virus R-HSA-202040 G-protein activation 24/1217 28/10654 2.582364518367732e-19 2.0135905611576237e-18 1.1784941339652876e-18 2788/54331/59345/2770/10681/51764/94235/5173/55970/5443/2792/346562/4988/2793/2785/2783/2784/2782/2786/2771/2791/2773/2790/2787 24 Myxoma_virus R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 24/1217 28/10654 2.582364518367732e-19 2.0135905611576237e-18 1.1784941339652876e-18 2788/54331/59345/2770/10681/51764/112/94235/150/55970/111/2792/152/775/2793/2785/2783/2784/2782/2786/2771/2791/2790/2787 24 Myxoma_virus R-HSA-5688426 Deubiquitination 90/1217 297/10654 4.102950310575984e-19 3.1791413727230265e-18 1.8606560494833163e-18 5718/5689/5684/8295/5720/5682/90865/2648/5700/122706/7321/5707/991/8237/4738/5690/9817/5717/9491/23198/409/6478/1080/143471/5706/5705/57695/4287/55031/10197/8517/64750/7316/10213/5709/993/5695/79155/890/4792/983/5714/2099/4609/7415/9861/5715/8850/7128/5711/5701/5688/5687/6502/4088/5685/5683/5698/5708/5692/5686/5713/324/2033/408/5699/8312/5710/5702/7157/8900/4087/63891/5719/5704/6233/123228/5716/7048/7311/114548/60/5694/7874/5693/5721/5696/5691/7314/4193 90 Myxoma_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 49/1217 108/10654 5.244079211309038e-19 4.037940992707959e-18 2.3632856972017707e-18 3605/7124/9655/7412/7184/207/9021/7422/3553/3082/5743/4318/4312/3383/301/3576/4313/3565/4985/6774/4314/5443/1026/3606/6772/8651/4609/4988/1901/3552/3717/598/2247/3320/2335/595/6288/7157/2353/6347/7076/7431/6356/3312/3569/3162/4170/3586/3596 49 Myxoma_virus R-HSA-176412 Phosphorylation of the APC/C 19/1217 19/10654 1.1051478242515123e-18 8.456783350794182e-18 4.949501533914913e-18 11065/246184/7321/8697/8881/891/983/51433/119504/51529/7324/64682/29945/10393/51434/25906/5347/29882/996 19 Myxoma_virus R-HSA-72766 Translation 88/1217 291/10654 1.2026314226990774e-18 9.14593773311891e-18 5.352842914547551e-18 6158/6138/6144/6203/6182/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/1917/1938/6147/56945/1915/6217/1936/6230/9255/6222/6176/6152/6136/6125/1937/6727/6224/6146/6141/26986/6202/64949/65003/6232/6169/6160/6164/6155/6175/6218/1933/6209/6193/6210/6229/11224/6205/6165/6142/6204/6228/23521/23107/140801/6156/6143/1973/6181/6124/740/6207/6233/2193/9801/7311/6223/25873/51386/3921/6188/6189/6135/6201/6161/9045/51649/6187/6168/6208/6157/6137/6122/6133 88 Myxoma_virus R-HSA-977444 GABA B receptor activation 28/1217 39/10654 1.4981415603432995e-18 1.1254331721603323e-17 6.586822649776382e-18 2788/54331/2770/2550/112/94235/114/108/113/55970/111/107/9568/2792/346562/2793/2785/2783/2784/2782/2786/2771/196883/115/109/2773/2790/2787 28 Myxoma_virus R-HSA-991365 Activation of GABAB receptors 28/1217 39/10654 1.4981415603432995e-18 1.1254331721603323e-17 6.586822649776382e-18 2788/54331/2770/2550/112/94235/114/108/113/55970/111/107/9568/2792/346562/2793/2785/2783/2784/2782/2786/2771/196883/115/109/2773/2790/2787 28 Myxoma_virus R-HSA-8878171 Transcriptional regulation by RUNX1 77/1217 239/10654 3.2895726842797815e-18 2.4562142709289036e-17 1.4375485095576715e-17 55904/5718/5689/27161/894/5684/5720/2624/1437/11091/6597/5682/5700/122706/5707/9021/5690/5717/9491/23198/143471/5706/5705/10197/200845/5196/7316/10213/5709/5695/28996/5714/6714/2099/9861/5715/8850/5711/5701/5688/1387/5687/3558/5685/5683/8289/5698/5708/5692/5686/5713/2033/1021/595/5699/8312/5710/3458/5702/83737/896/5719/5371/23112/5704/6233/5716/7311/7161/3276/5694/1493/5693/5721/5696/5691/7314 77 Myxoma_virus R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 25/1217 32/10654 3.3823876996070184e-18 2.5103021963348473e-17 1.4692045492903032e-17 2788/2149/54331/59345/5594/10681/409/51764/94235/2769/55970/2792/6714/2793/408/2785/2783/2784/2782/2786/9630/2791/5595/2790/2787 25 Myxoma_virus R-HSA-391251 Protein folding 46/1217 101/10654 5.2795363282449615e-18 3.8948435667052654e-17 2.279535067663283e-17 2788/10694/26224/9134/54331/22803/59345/2770/8237/10575/10382/10681/898/51764/7277/94235/10517/10576/55970/6774/2792/26272/346562/2793/26270/2785/55294/2783/26190/2784/2782/81027/7157/2786/2771/6468/10383/60/54461/84790/26234/2791/84261/2773/2790/2787 46 Myxoma_virus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 24/1217 30/10654 5.962774278589028e-18 4.372701137631954e-17 2.5592107649332614e-17 11065/7319/7321/65264/7320/10477/92912/7326/7316/7317/54926/55236/3093/7322/7328/7324/6233/7327/7311/55284/27338/7874/997/7314 24 Myxoma_virus R-HSA-111885 Opioid Signalling 43/1217 91/10654 1.1597321413286712e-17 8.454378687082384e-17 4.9480941564007466e-17 2788/3838/54331/59345/2770/5594/10681/51764/112/94235/114/108/113/5173/5528/55970/111/107/5443/2792/346562/5519/4988/2793/2785/2783/2784/2782/2786/5499/2771/5518/196883/115/801/2791/109/2773/2790/805/5515/2787/5516 43 Myxoma_virus R-HSA-450604 KSRP (KHSRP) binds and destabilizes mRNA 17/1217 17/10654 8.689953084251322e-17 6.297660117528017e-16 3.685831493939416e-16 5393/23404/5073/207/7534/1432/51013/11340/51010/5600/56915/8570/23016/54512/118460/167227/22894 17 Myxoma_virus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 21/1217 25/10654 1.1255620649759678e-16 8.062165488665072e-16 4.718543540443929e-16 11065/246184/7321/991/8697/8881/7316/51433/119504/51529/7324/64682/29945/10393/6233/51434/7311/25906/29882/7314/996 21 Myxoma_virus R-HSA-418592 ADP signalling through P2Y purinoceptor 1 21/1217 25/10654 1.1255620649759678e-16 8.062165488665072e-16 4.718543540443929e-16 2788/54331/59345/10681/51764/94235/2769/55970/2792/6714/1432/2793/2785/2783/2784/2782/2786/9630/2791/2790/2787 21 Myxoma_virus R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 18/1217 19/10654 1.663731380926164e-16 1.1848075498849909e-015 6.934323066227092e-16 11065/246184/7321/991/8697/8881/51433/119504/51529/7324/64682/29945/10393/51434/51343/25906/29882/996 18 Myxoma_virus R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs 51/1217 130/10654 1.920607298003254e-16 1.3598782707701202e-15 7.958959462384932e-16 5718/5689/5684/5720/2624/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/83737/5719/5704/6233/5716/7311/7161/5694/5693/5721/5696/5691/7314 51 Myxoma_virus R-HSA-69231 Cyclin D associated events in G1 28/1217 44/10654 2.104000532948284e-16 1.4728003730637988e-15 8.619858642760614e-16 8454/894/1019/7027/1027/6500/5934/7316/1869/1875/1026/6714/5519/4067/3717/6502/1021/1874/595/896/6233/7311/5518/1163/1028/7314/5515/5516 28 Myxoma_virus R-HSA-69236 G1 Phase 28/1217 44/10654 2.104000532948284e-16 1.4728003730637988e-15 8.619858642760614e-16 8454/894/1019/7027/1027/6500/5934/7316/1869/1875/1026/6714/5519/4067/3717/6502/1021/1874/595/896/6233/7311/5518/1163/1028/7314/5515/5516 28 Myxoma_virus R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 30/1217 51/10654 4.074546599716993e-16 2.8360685937013194e-15 1.6598658464502768e-15 6203/6227/6206/6194/6234/6191/6217/6230/6222/6224/6202/6232/6218/6209/6193/6210/6229/6205/6204/6228/6207/6233/6223/51386/3921/6188/6189/6201/6187/6208 30 Myxoma_virus R-HSA-162906 HIV Infection 72/1217 233/10654 5.219951077317804e-16 3.612909959132323e-15 2.1145277870861597e-15 5718/5689/8945/5684/5903/8065/7852/5720/5682/5700/122706/5707/5430/5690/7518/5717/4869/9491/23198/6500/6749/143471/5706/5705/10197/4686/7316/10213/5709/9978/293/5695/292/3055/5714/8148/8731/9861/5715/5711/23327/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5478/5719/3836/5704/6233/5716/1025/7311/5694/22916/5693/1234/5721/5696/5691/8480/940/7314 72 Myxoma_virus R-HSA-72649 Translation initiation complex formation 32/1217 58/10654 5.541572293559651e-16 3.814087746181838e-15 2.2322711091375246e-15 6203/6227/6206/6194/6234/6191/6217/6230/6222/6224/26986/6202/6232/6218/6209/6193/6210/6229/6205/6204/6228/1973/6207/6233/6223/51386/3921/6188/6189/6201/6187/6208 32 Myxoma_virus R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 32/1217 59/10654 1.0800430683477797e-15 7.392294778913692e-15 4.326488314726486e-15 6203/6227/6206/6194/6234/6191/6217/6230/6222/6224/26986/6202/6232/6218/6209/6193/6210/6229/6205/6204/6228/1973/6207/6233/6223/51386/3921/6188/6189/6201/6187/6208 32 Myxoma_virus R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 27/1217 43/10654 1.1971003878543482e-15 8.148219214566614e-15 4.768908204014124e-15 2788/54331/59345/10681/51764/112/94235/114/108/113/8766/55970/111/107/2792/2793/2785/2783/2784/2782/2786/196883/115/2791/109/2790/2787 27 Myxoma_virus R-HSA-8964315 G beta:gamma signalling through BTK 17/1217 18/10654 1.3975326824391662e-15 9.460221234972818e-15 5.5367836175293746e-15 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Myxoma_virus R-HSA-168898 Toll-like Receptor Cascades 55/1217 155/10654 2.2227924893216797e-15 1.496437348002355e-14 8.75819876436785e-15 54106/8454/1147/3725/8945/1326/351/81793/4790/7184/7321/29110/5594/6500/10333/7099/8517/4615/7098/7100/5528/7323/7316/79155/7335/5970/4792/7096/4793/6279/8651/7322/5519/1432/23291/6288/3661/3654/6233/51311/2353/7311/1759/5518/5599/5600/7334/7097/3551/4791/51284/7314/5595/5515/5516 55 Myxoma_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 41/1217 94/10654 2.2454485790018094e-15 1.503474265940342e-14 8.799383733502514e-15 8454/1147/3725/8945/1326/351/4790/7321/29110/5594/6500/8517/7098/5528/7323/7316/79155/7335/5970/4792/4793/7322/5519/1432/23291/6288/3661/3654/6233/2353/7311/5518/5599/5600/7334/3551/4791/7314/5595/5515/5516 41 Myxoma_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 41/1217 95/10654 3.5227703694058223e-15 2.3333618790903082e-14 1.3656466910260262e-14 8454/1147/3725/8945/1326/351/4790/5594/6500/10333/7099/8517/4615/5528/7316/79155/7335/5970/4792/7096/4793/8651/5519/1432/23291/6288/3654/6233/2353/7311/5518/5599/5600/7334/7097/3551/4791/7314/5595/5515/5516 41 Myxoma_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 41/1217 95/10654 3.5227703694058223e-15 2.3333618790903082e-14 1.3656466910260262e-14 8454/1147/3725/8945/1326/351/4790/5594/6500/10333/7099/8517/4615/5528/7316/79155/7335/5970/4792/7096/4793/8651/5519/1432/23291/6288/3654/6233/2353/7311/5518/5599/5600/7334/7097/3551/4791/7314/5595/5515/5516 41 Myxoma_virus R-HSA-392451 G beta:gamma signalling through PI3Kgamma 20/1217 25/10654 3.752663546559801e-15 2.4723430424393982e-14 1.4469881955493745e-14 2788/54331/59345/207/10681/51764/94235/55970/2792/2793/10000/2785/2783/2784/2782/2786/208/2791/2790/2787 20 Myxoma_virus R-HSA-72702 Ribosomal scanning and start codon recognition 31/1217 58/10654 5.252543696436357e-15 3.425084061028244e-14 2.0045989249866267e-14 6203/6227/6206/6194/6234/6191/6217/6230/6222/6224/6202/6232/6218/6209/6193/6210/6229/6205/6204/6228/1973/6207/6233/6223/51386/3921/6188/6189/6201/6187/6208 31 Myxoma_virus R-HSA-163359 Glucagon signaling in metabolic regulation 23/1217 33/10654 5.254390320895602e-15 3.425084061028244e-14 2.0045989249866267e-14 2788/54331/59345/51764/112/94235/114/108/113/55970/111/107/2785/2783/2784/2782/2786/196883/115/2791/109/2790/2787 23 Myxoma_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 40/1217 92/10654 5.642152373098141e-15 3.6584903808720574e-14 2.1412046402062197e-14 54106/8454/1147/3725/8945/1326/351/4790/5594/6500/7099/8517/4615/5528/7316/79155/7335/5970/4792/4793/5519/1432/23291/6288/3654/6233/51311/2353/7311/5518/5599/5600/7334/3551/4791/51284/7314/5595/5515/5516 40 Myxoma_virus R-HSA-428930 Thromboxane signalling through TP receptor 19/1217 23/10654 6.223763682420655e-15 4.014490500912171e-14 2.34956082802874e-14 2788/54331/59345/10681/51764/94235/2769/55970/2792/2793/2785/2783/2784/2782/2786/9630/2791/2790/2787 19 Myxoma_virus R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 15/1217 15/10654 6.8128801897220665e-15 4.26064385468913e-14 2.493626999711256e-14 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Myxoma_virus R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 15/1217 15/10654 6.8128801897220665e-15 4.26064385468913e-14 2.493626999711256e-14 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Myxoma_virus R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 15/1217 15/10654 6.8128801897220665e-15 4.26064385468913e-14 2.493626999711256e-14 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Myxoma_virus R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 15/1217 15/10654 6.8128801897220665e-15 4.26064385468913e-14 2.493626999711256e-14 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Myxoma_virus R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 15/1217 15/10654 6.8128801897220665e-15 4.26064385468913e-14 2.493626999711256e-14 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Myxoma_virus R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 15/1217 15/10654 6.8128801897220665e-15 4.26064385468913e-14 2.493626999711256e-14 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Myxoma_virus R-HSA-72163 mRNA Splicing - Major Pathway 60/1217 183/10654 7.647627435791901e-15 4.758523737826072e-14 2.7850211555116704e-14 10921/23451/6635/6633/220988/6432/6431/6430/6632/27339/23350/5430/4904/6428/3184/8106/3178/6637/23450/3183/5093/4686/6625/11338/1655/3185/3190/6626/7307/6429/22938/988/10236/6629/4670/10189/6434/6631/10949/3181/1660/2521/3191/3187/1665/10286/6634/5094/9775/3192/6427/3312/6426/3188/22916/5725/11100/10262/6628/1994 60 Myxoma_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 40/1217 93/10654 8.82890071804978e-15 5.4275279562102524e-14 3.1765692498325554e-14 54106/8454/1147/3725/8945/1326/351/4790/5594/6500/7099/8517/4615/5528/7316/79155/7335/5970/4792/4793/5519/1432/23291/6288/3654/6233/51311/2353/7311/5518/5599/5600/7334/3551/4791/51284/7314/5595/5515/5516 40 Myxoma_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 40/1217 93/10654 8.82890071804978e-15 5.4275279562102524e-14 3.1765692498325554e-14 54106/8454/1147/3725/8945/1326/351/4790/5594/6500/7099/8517/4615/5528/7316/79155/7335/5970/4792/4793/5519/1432/23291/6288/3654/6233/51311/2353/7311/5518/5599/5600/7334/3551/4791/51284/7314/5595/5515/5516 40 Myxoma_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 38/1217 85/10654 8.943085836937348e-15 5.4275279562102524e-14 3.1765692498325554e-14 8454/1147/3725/8945/1326/351/81793/4790/5594/6500/8517/4615/7100/5528/7316/79155/7335/5970/4792/4793/5519/1432/23291/6288/3654/6233/2353/7311/5518/5599/5600/7334/3551/4791/7314/5595/5515/5516 38 Myxoma_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 38/1217 85/10654 8.943085836937348e-15 5.4275279562102524e-14 3.1765692498325554e-14 8454/1147/3725/8945/1326/351/81793/4790/5594/6500/8517/4615/7100/5528/7316/79155/7335/5970/4792/4793/5519/1432/23291/6288/3654/6233/2353/7311/5518/5599/5600/7334/3551/4791/7314/5595/5515/5516 38 Myxoma_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 38/1217 85/10654 8.943085836937348e-15 5.4275279562102524e-14 3.1765692498325554e-14 8454/1147/3725/8945/1326/351/81793/4790/5594/6500/8517/4615/7100/5528/7316/79155/7335/5970/4792/4793/5519/1432/23291/6288/3654/6233/2353/7311/5518/5599/5600/7334/3551/4791/7314/5595/5515/5516 38 Myxoma_virus R-HSA-392851 Prostacyclin signalling through prostacyclin receptor 17/1217 19/10654 1.1862388809384726e-14 7.163952457432345e-14 4.1928464057938795e-14 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Myxoma_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 41/1217 98/10654 1.2986229477948232e-14 7.766521707200107e-14 4.545512106486735e-14 8454/1147/3725/8945/1326/351/4790/5594/6500/10333/7099/8517/4615/5528/7316/79155/7335/5970/4792/7096/4793/8651/5519/1432/23291/6288/3654/6233/2353/7311/5518/5599/5600/7334/7097/3551/4791/7314/5595/5515/5516 41 Myxoma_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 41/1217 98/10654 1.2986229477948232e-14 7.766521707200107e-14 4.545512106486735e-14 8454/1147/3725/8945/1326/351/4790/5594/6500/10333/7099/8517/4615/5528/7316/79155/7335/5970/4792/7096/4793/8651/5519/1432/23291/6288/3654/6233/2353/7311/5518/5599/5600/7334/7097/3551/4791/7314/5595/5515/5516 41 Myxoma_virus R-HSA-166166 MyD88-independent TLR4 cascade 41/1217 99/10654 1.976708002197016e-14 1.1708193551474633e-13 6.852454359842895e-14 8454/1147/3725/8945/1326/351/4790/7321/29110/5594/6500/7099/8517/5528/7323/7316/79155/7335/5970/4792/4793/7322/5519/1432/23291/6288/3661/3654/6233/2353/7311/5518/5599/5600/7334/3551/4791/7314/5595/5515/5516 41 Myxoma_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 41/1217 99/10654 1.976708002197016e-14 1.1708193551474633e-13 6.852454359842895e-14 8454/1147/3725/8945/1326/351/4790/7321/29110/5594/6500/7099/8517/5528/7323/7316/79155/7335/5970/4792/4793/7322/5519/1432/23291/6288/3661/3654/6233/2353/7311/5518/5599/5600/7334/3551/4791/7314/5595/5515/5516 41 Myxoma_virus R-HSA-68886 M Phase 98/1217 395/10654 2.5787749193312704e-14 1.5201199524479066e-13 8.896805941787563e-14 5718/5689/26271/5684/5903/5720/11065/54908/5682/246184/5525/7531/5700/122706/7321/5707/991/203068/5526/8697/5690/10382/5594/5717/9491/23198/7277/143471/5706/5705/10197/6232/8881/5528/7316/10213/5709/891/5695/5501/8655/983/5714/10121/51433/9861/5715/5519/5711/5701/5688/1062/5687/5685/5683/5698/5708/3320/5692/5686/5713/119504/5699/5529/5710/5702/81027/51529/7324/5719/64682/29945/10393/9232/5704/6233/5527/23175/51434/5716/7311/5518/25906/10383/5347/84790/29882/5694/5693/5721/5696/5691/8480/7314/996/5595/5515/5516 98 Myxoma_virus R-HSA-6783783 Interleukin-10 signaling 27/1217 47/10654 2.7920452888261576e-14 1.6379999027780123e-13 9.586721919027157e-14 729230/3557/7124/1437/6351/3553/1230/2919/5743/3383/3576/2357/2920/6352/6774/6348/1440/3627/3606/6364/3552/6363/6347/7076/3569/1234/3586 27 Myxoma_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 40/1217 97/10654 4.8978480478212156e-14 2.859786158727838e-13 1.673747025571231e-13 54106/8454/1147/3725/8945/1326/351/4790/5594/6500/7099/8517/4615/5528/7316/79155/7335/5970/4792/4793/5519/1432/23291/6288/3654/6233/51311/2353/7311/5518/5599/5600/7334/3551/4791/51284/7314/5595/5515/5516 40 Myxoma_virus R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 14/1217 14/10654 6.025689544359339e-14 3.4210366445394956e-13 2.0022300935659218e-13 5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 14 Myxoma_virus R-HSA-4839744 truncated APC mutants destabilize the destruction complex 14/1217 14/10654 6.025689544359339e-14 3.4210366445394956e-13 2.0022300935659218e-13 5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 14 Myxoma_virus R-HSA-4839748 AMER1 mutants destabilize the destruction complex 14/1217 14/10654 6.025689544359339e-14 3.4210366445394956e-13 2.0022300935659218e-13 5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 14 Myxoma_virus R-HSA-5467337 APC truncation mutants have impaired AXIN binding 14/1217 14/10654 6.025689544359339e-14 3.4210366445394956e-13 2.0022300935659218e-13 5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 14 Myxoma_virus R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 14/1217 14/10654 6.025689544359339e-14 3.4210366445394956e-13 2.0022300935659218e-13 5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 14 Myxoma_virus R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 14/1217 14/10654 6.025689544359339e-14 3.4210366445394956e-13 2.0022300935659218e-13 5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 14 Myxoma_virus R-HSA-72172 mRNA Splicing 60/1217 191/10654 6.703253799250545e-14 3.7882608626957205e-13 2.2171554092161386e-13 10921/23451/6635/6633/220988/6432/6431/6430/6632/27339/23350/5430/4904/6428/3184/8106/3178/6637/23450/3183/5093/4686/6625/11338/1655/3185/3190/6626/7307/6429/22938/988/10236/6629/4670/10189/6434/6631/10949/3181/1660/2521/3191/3187/1665/10286/6634/5094/9775/3192/6427/3312/6426/3188/22916/5725/11100/10262/6628/1994 60 Myxoma_virus R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 17/1217 20/10654 7.066139942204459e-14 3.921389373331484e-13 2.295071531725963e-13 11065/246184/7321/991/8697/8881/51433/119504/51529/7324/64682/29945/10393/51434/25906/29882/996 17 Myxoma_virus R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 17/1217 20/10654 7.066139942204459e-14 3.921389373331484e-13 2.295071531725963e-13 11065/246184/7321/991/8697/8881/51433/119504/51529/7324/64682/29945/10393/51434/25906/29882/996 17 Myxoma_virus R-HSA-418217 G beta:gamma signalling through PLC beta 17/1217 20/10654 7.066139942204459e-14 3.921389373331484e-13 2.295071531725963e-13 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Myxoma_virus R-HSA-8964616 G beta:gamma signalling through CDC42 17/1217 20/10654 7.066139942204459e-14 3.921389373331484e-13 2.295071531725963e-13 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Myxoma_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 47/1217 129/10654 7.946222758153643e-14 4.390020824235555e-13 2.569347457793366e-13 8454/1147/3725/8945/1326/351/4790/7321/29110/5594/6500/10333/7099/8517/4615/5528/7323/7316/79155/7335/5970/4792/7096/4793/8651/7322/5519/1432/23291/6288/3661/3654/6233/2353/7311/1759/5518/5599/5600/7334/7097/3551/4791/7314/5595/5515/5516 47 Myxoma_virus R-HSA-977443 GABA receptor activation 29/1217 56/10654 1.1862207546230037e-13 6.524214150426521e-13 3.818426771225365e-13 2788/54331/2770/2550/112/94235/114/108/113/55970/111/107/9568/2792/346562/2793/2785/2783/2784/2782/2786/2771/196883/115/2560/109/2773/2790/2787 29 Myxoma_virus R-HSA-500657 Presynaptic function of Kainate receptors 17/1217 21/10654 3.314804073775801e-13 1.8150393861741274e-12 1.0622880891398474e-12 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Myxoma_virus R-HSA-196299 Beta-catenin phosphorylation cascade 15/1217 17/10654 7.407003086863391e-13 4.037799912838804e-12 2.3632031273877142e-12 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Myxoma_virus R-HSA-445717 Aquaporin-mediated transport 27/1217 52/10654 7.721654303880493e-13 4.190783305013554e-12 2.4527397162801477e-12 2788/54331/59345/10681/51764/112/94235/114/108/113/8766/55970/111/107/2792/2793/2785/2783/2784/2782/2786/196883/115/2791/109/2790/2787 27 Myxoma_virus R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 24/1217 42/10654 9.061042952557675e-13 4.896142507697832e-12 2.8655652920138543e-12 2788/10694/54331/59345/2770/10575/10681/51764/94235/10576/55970/2792/346562/2793/2785/2783/2784/2782/2786/2771/2791/2773/2790/2787 24 Myxoma_virus R-HSA-6804757 Regulation of TP53 Degradation 22/1217 36/10654 1.2193383795048303e-12 6.559933989301096e-12 3.8393325210793325e-12 1017/207/11200/7316/890/80196/983/5519/10000/7157/8900/208/6233/5527/7311/5518/7874/7314/253260/4193/5515/5516 22 Myxoma_virus R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 41/1217 110/10654 1.310760364099548e-12 7.021116385089753e-12 4.109248738710253e-12 1017/3725/1019/11065/4790/246184/7321/8697/5594/1027/1051/79813/3576/8881/7316/890/6774/5970/1026/51433/3552/1021/119504/8900/51529/7324/64682/29945/10393/6233/51434/2353/51343/7311/25906/29882/3569/10919/7314/996/5595 41 Myxoma_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 22/1217 37/10654 2.6850392591143336e-12 1.4320209381943113e-11 8.381188847087349e-12 1017/207/11200/7316/890/80196/983/5519/10000/7157/8900/208/6233/5527/7311/5518/7874/7314/253260/4193/5515/5516 22 Myxoma_virus R-HSA-163685 Integration of energy metabolism 40/1217 108/10654 3.1269140825316984e-12 1.6604992024478674e-11 9.718403568667031e-12 2788/54331/59345/2770/10681/51764/112/94235/114/108/2769/150/113/5528/55970/111/107/2792/152/5519/775/2793/2785/2783/2784/2782/3630/2786/2771/9370/5518/196883/115/9630/2791/109/2790/5515/2787/5516 40 Myxoma_virus R-HSA-5619115 Disorders of transmembrane transporters 54/1217 176/10654 3.4893286790415726e-12 1.84500125861769e-11 1.0798238740200938e-11 5718/5689/5684/5903/5720/5682/5700/122706/5707/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/213/5694/5693/5721/5696/5691/8480/11136/7314 54 Myxoma_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 14/1217 16/10654 5.785563195775753e-12 3.0460742979468925e-11 1.7827758835386376e-11 8454/1147/8945/1326/4790/6500/8517/7316/79155/23291/6233/7311/3551/7314 14 Myxoma_virus R-HSA-170670 Adenylate cyclase inhibitory pathway 13/1217 14/10654 6.6724001780155675e-12 3.4980412848149696e-11 2.0472985988536013e-11 2770/112/114/108/113/111/107/346562/2771/196883/115/109/2773 13 Myxoma_virus R-HSA-397795 G-protein beta:gamma signalling 20/1217 32/10654 7.220150107796526e-12 3.7691631071208986e-11 2.2059780659414007e-11 2788/54331/59345/207/10681/51764/94235/55970/2792/2793/10000/2785/2783/2784/2782/2786/208/2791/2790/2787 20 Myxoma_virus R-HSA-450294 MAP kinase activation 29/1217 64/10654 8.950340173576041e-12 4.6526662843230726e-11 2.7230659644235346e-11 8454/1147/3725/8945/1326/4790/5594/6500/8517/5528/7316/79155/7335/5519/1432/23291/3654/6233/2353/7311/5518/5599/5600/7334/3551/7314/5595/5515/5516 29 Myxoma_virus R-HSA-982772 Growth hormone receptor signaling 17/1217 24/10654 1.3678596455166773e-11 7.080685223851036e-11 4.144112592564901e-11 3667/2690/9021/5594/6774/6772/8651/1442/4067/3717/5618/2688/1154/5617/8835/2689/5595 17 Myxoma_virus R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress 18/1217 27/10654 1.6644875925764185e-11 8.580120142485973e-11 5.0216868571453284e-11 5393/23404/5073/1051/1649/3576/468/51013/6347/11340/51010/56915/8570/23016/54512/118460/167227/22894 18 Myxoma_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 24/1217 47/10654 2.339414347491075e-11 1.2008993650454185e-10 7.028503631716607e-11 8454/2648/892/55534/3280/6500/84441/10013/10046/7316/9978/1024/4609/22938/8850/1387/2033/55294/9794/6233/7311/3516/4851/7314 24 Myxoma_virus R-HSA-2559583 Cellular Senescence 56/1217 195/10654 2.6410035426327944e-11 1.3500897778106235e-10 7.901670350309955e-11 1017/3725/9134/1019/11065/4790/246184/7027/7321/2146/8697/5594/1027/898/7295/1051/79813/3576/8881/7316/1869/890/6774/5970/1026/51433/3552/1432/1021/119504/25842/7157/8900/51529/7324/64682/29945/10393/23112/6233/51434/2353/51343/7311/25906/8726/29882/5599/5600/3456/3569/10919/7314/996/5595/4193 56 Myxoma_virus R-HSA-448424 Interleukin-17 signaling 30/1217 72/10654 5.312178590785347e-11 2.704381828036177e-10 1.5827935340095536e-10 8454/3605/1147/3725/8945/1326/4790/5594/6500/8517/5528/7316/79155/7335/5519/1432/23291/3654/6233/2353/7311/5518/5599/5600/7334/3551/7314/5595/5515/5516 30 Myxoma_virus R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 15/1217 20/10654 6.037471817484509e-11 3.060973365901611e-10 1.7914958609386564e-10 2648/55534/3280/84441/10046/22938/8850/1387/4088/59/2033/4855/9794/3516/4851 15 Myxoma_virus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 64/1217 244/10654 7.5511426324531e-11 3.812708083271402e-10 2.231463633835364e-10 10921/23451/6635/5903/6633/220988/6432/6431/6430/6632/7884/27339/23350/5430/4904/6428/3184/8106/3178/6637/23450/3183/5093/4686/6625/11338/1655/3185/3190/6626/7307/6429/22938/988/10236/6629/4670/10189/6434/6631/10482/10949/3181/1660/2521/3191/3187/1665/10286/6634/5094/9775/3192/6427/3312/6426/3188/22916/5725/11100/8480/10262/6628/1994 64 Myxoma_virus R-HSA-381042 PERK regulates gene expression 19/1217 32/10654 8.832867058322866e-11 4.423614721891777e-10 2.5890089580449995e-10 5393/23404/5073/1051/1649/3576/468/3309/51013/6347/11340/51010/56915/8570/23016/54512/118460/167227/22894 19 Myxoma_virus R-HSA-451326 Activation of kainate receptors upon glutamate binding 19/1217 32/10654 8.832867058322866e-11 4.423614721891777e-10 2.5890089580449995e-10 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/801/2791/2790/805/2787 19 Myxoma_virus R-HSA-8852135 Protein ubiquitination 31/1217 79/10654 1.5916880137661363e-10 7.939107825748501e-10 4.6465215829098804e-10 11065/7319/7321/65264/7320/10477/92912/79577/7336/7326/7323/7316/7317/54926/55236/5111/7415/3093/7322/118424/7328/7324/6233/7327/7311/55284/27338/7334/7874/997/7314 31 Myxoma_virus R-HSA-389513 CTLA4 inhibitory signaling 15/1217 21/10654 1.889730624923746e-10 9.387694072201836e-10 5.494335645470144e-10 5525/5526/207/5528/6714/5519/4067/10000/5529/208/5527/5518/1493/5515/5516 15 Myxoma_virus R-HSA-8941856 RUNX3 regulates NOTCH signaling 12/1217 14/10654 3.4322774963301e-10 1.698219227099873e-9 9.939167554369558e-10 2648/55534/3280/84441/10046/22938/8850/1387/2033/9794/3516/4851 12 Myxoma_virus R-HSA-8939211 ESR-mediated signaling 58/1217 223/10654 8.428595314697807e-10 4.153611771083079e-9 2.430984332870736e-9 2788/27161/3725/3838/54331/59345/5430/2770/207/1903/5594/1027/10681/51764/94235/4318/200845/4313/1950/55970/1655/4314/2792/346562/6714/2099/4609/8850/1387/2793/10000/3320/2033/2785/595/2783/2784/8312/2782/2786/23112/2771/208/10498/3326/1025/2353/1956/3276/3265/801/2791/2773/5595/2790/805/2787/6387 58 Myxoma_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 25/1217 58/10654 9.087079649915053e-10 4.3903067171354295e-9 2.569514782328921e-9 8454/142678/2648/892/55534/3280/6500/84441/10013/10046/7316/9978/1024/4609/22938/8850/1387/2033/55294/9794/6233/7311/3516/4851/7314 25 Myxoma_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 25/1217 58/10654 9.087079649915053e-10 4.3903067171354295e-9 2.569514782328921e-9 8454/142678/2648/892/55534/3280/6500/84441/10013/10046/7316/9978/1024/4609/22938/8850/1387/2033/55294/9794/6233/7311/3516/4851/7314 25 Myxoma_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 25/1217 58/10654 9.087079649915053e-10 4.3903067171354295e-9 2.569514782328921e-9 8454/142678/2648/892/55534/3280/6500/84441/10013/10046/7316/9978/1024/4609/22938/8850/1387/2033/55294/9794/6233/7311/3516/4851/7314 25 Myxoma_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 25/1217 58/10654 9.087079649915053e-10 4.3903067171354295e-9 2.569514782328921e-9 8454/142678/2648/892/55534/3280/6500/84441/10013/10046/7316/9978/1024/4609/22938/8850/1387/2033/55294/9794/6233/7311/3516/4851/7314 25 Myxoma_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 25/1217 58/10654 9.087079649915053e-10 4.3903067171354295e-9 2.569514782328921e-9 8454/142678/2648/892/55534/3280/6500/84441/10013/10046/7316/9978/1024/4609/22938/8850/1387/2033/55294/9794/6233/7311/3516/4851/7314 25 Myxoma_virus R-HSA-1980143 Signaling by NOTCH1 28/1217 73/10654 2.26473112084891e-9 1.0899018519085381e-8 6.378868494167367e-9 8454/142678/2648/892/55534/3280/6500/409/84441/10013/10046/7316/9978/1024/4609/22938/8850/1387/2033/408/55294/83737/9794/6233/7311/3516/4851/7314 28 Myxoma_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 29/1217 78/10654 2.7491411122455196e-9 1.3178762063371518e-8 7.713133982749051e-9 1147/351/4790/7321/29110/8517/7323/7316/5970/4792/4793/3093/7322/7128/1387/2033/6288/83737/3661/9246/51191/6233/7311/7318/5094/3551/3456/4791/7314 29 Myxoma_virus R-HSA-5260271 Diseases of Immune System 15/1217 24/10654 3.2575293360363697e-9 1.5495274679524356e-8 9.068919305770835e-9 1147/81793/4790/10333/7099/8517/4615/7098/7100/5970/4792/7096/7097/3551/4791 15 Myxoma_virus R-HSA-5602358 Diseases associated with the TLR signaling cascade 15/1217 24/10654 3.2575293360363697e-9 1.5495274679524356e-8 9.068919305770835e-9 1147/81793/4790/10333/7099/8517/4615/7098/7100/5970/4792/7096/7097/3551/4791 15 Myxoma_virus R-HSA-418346 Platelet homeostasis 31/1217 88/10654 3.6193080537797747e-9 1.714995200867955e-8 1.0037352294895328e-8 2788/54331/5525/59345/5526/2268/10681/51764/94235/5528/55970/2792/5519/3778/1432/2793/2785/2783/2784/5529/2782/2786/5527/5518/801/2791/2790/805/5515/2787/5516 31 Myxoma_virus R-HSA-9012852 Signaling by NOTCH3 22/1217 49/10654 3.657370369525011e-9 1.7263909177221506e-8 1.010404800614895e-8 142678/2648/4904/55534/3280/84441/10046/7316/1950/6772/11060/22938/8850/1387/2033/9794/6233/7311/1956/3516/4851/7314 22 Myxoma_virus R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 20/1217 42/10654 5.308083401002378e-9 2.4960147900896676e-8 1.4608425591348451e-8 2788/54331/59345/10681/51764/112/94235/114/55970/111/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 20 Myxoma_virus R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 12/1217 16/10654 5.506553678153123e-9 2.5794958674846568e-8 1.5097015287311945e-8 2648/55534/3280/84441/10046/22938/8850/1387/2033/9794/3516/4851 12 Myxoma_virus R-HSA-1296041 Activation of G protein gated Potassium channels 15/1217 25/10654 7.284350817113892e-9 3.373804588979066e-8 1.974586588730913e-8 2788/54331/2550/94235/55970/9568/2792/2793/2785/2783/2784/2782/2786/2790/2787 15 Myxoma_virus R-HSA-1296059 G protein gated Potassium channels 15/1217 25/10654 7.284350817113892e-9 3.373804588979066e-8 1.974586588730913e-8 2788/54331/2550/94235/55970/9568/2792/2793/2785/2783/2784/2782/2786/2790/2787 15 Myxoma_virus R-HSA-997272 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits 15/1217 25/10654 7.284350817113892e-9 3.373804588979066e-8 1.974586588730913e-8 2788/54331/2550/94235/55970/9568/2792/2793/2785/2783/2784/2782/2786/2790/2787 15 Myxoma_virus R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 19/1217 39/10654 7.960985276296026e-9 3.6733834683133716e-8 2.1499211173911995e-8 10694/26224/9134/22803/8237/10575/898/10517/10576/6774/26272/26270/55294/26190/7157/6468/54461/26234/84261 19 Myxoma_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 23/1217 55/10654 8.718452525485585e-9 4.007885638581433e-8 2.3456952002975753e-8 1147/834/351/4790/7295/8517/7316/7335/5970/7128/1432/598/83737/3654/6233/3326/7311/114548/5600/7334/3551/4791/7314 23 Myxoma_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 27/1217 73/10654 1.1035424107343333e-8 5.0541421934003664e-8 2.9580377669850065e-8 57154/892/7027/7321/10273/4738/64750/7323/54778/7316/1875/5501/1024/4609/22938/23327/4088/1874/9040/4087/5499/6233/7048/1025/7311/7314/5054 27 Myxoma_virus R-HSA-422356 Regulation of insulin secretion 28/1217 78/10654 1.2771186130088482e-8 5.827444930470004e-8 3.41062865462402e-8 2788/54331/59345/2770/10681/51764/112/94235/114/2769/150/55970/111/2792/152/775/2793/2785/2783/2784/2782/3630/2786/2771/9630/2791/2790/2787 28 Myxoma_virus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 20/1217 44/10654 1.4518918994750869e-8 6.600482731193015e-8 3.8630644829692544e-8 892/7027/7321/64750/7323/54778/7316/1875/1024/4609/22938/23327/4088/1874/4087/6233/1025/7311/7314/5054 20 Myxoma_virus R-HSA-450385 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA 12/1217 17/10654 1.6770301619702275e-8 7.549239521290717e-8 4.418343363024729e-8 5393/23404/207/51013/11340/51010/56915/23016/54512/118460/167227/22894 12 Myxoma_virus R-HSA-420092 Glucagon-type ligand receptors 17/1217 33/10654 1.6789704779493966e-8 7.549239521290717e-8 4.418343363024729e-8 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Myxoma_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 17/1217 33/10654 1.6789704779493966e-8 7.549239521290717e-8 4.418343363024729e-8 1147/351/4790/8517/7316/7335/5970/4792/4793/6288/3654/6233/7311/7334/3551/4791/7314 17 Myxoma_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 13/1217 20/10654 1.900564156615831e-8 8.514527421638924e-8 4.983297405863519e-8 1147/7321/8517/7098/7323/7316/7335/7322/6233/7311/7334/3551/7314 13 Myxoma_virus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 21/1217 49/10654 2.29408326948714e-8 1.0240255753652741e-7 5.993314414945427e-8 1017/9134/7027/7832/1027/4869/898/5934/1869/891/890/983/1026/6790/5111/2033/1874/7157/8900/10498/3276 21 Myxoma_virus R-HSA-4086398 Ca2+ pathway 24/1217 62/10654 2.563359599690179e-8 1.140093511486751e-7 6.672625216750038e-8 2788/27161/54331/1499/59345/51701/10681/51764/94235/55970/2792/6934/2793/2785/2783/2784/2782/2786/23112/801/2791/2790/805/2787 24 Myxoma_virus R-HSA-170660 Adenylate cyclase activating pathway 9/1217 10/10654 2.896038096071296e-8 1.283424077107855e-7 7.511496008363643e-8 112/114/108/113/111/107/196883/115/109 9 Myxoma_virus R-HSA-4791275 Signaling by WNT in cancer 17/1217 34/10654 3.001969993353467e-8 1.3256010866707782e-7 7.758345389349652e-8 1499/5525/139285/5526/1452/27121/5528/6934/5519/2932/324/8312/5529/5527/5518/5515/5516 17 Myxoma_virus R-HSA-1538133 G0 and Early G1 15/1217 27/10654 3.099889850694673e-8 1.363951534305656e-7 7.982799051600944e-8 1017/9134/7027/898/5934/1869/1875/993/890/983/5111/4609/990/1874/8900 15 Myxoma_virus R-HSA-1170546 Prolactin receptor signaling 11/1217 15/10654 3.655541111031509e-8 1.5970307265215672e-7 9.346941623951413e-8 8454/8945/2690/6500/9978/1442/3717/5618/2688/5617/2689 11 Myxoma_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 11/1217 15/10654 3.655541111031509e-8 1.5970307265215672e-7 9.346941623951413e-8 54106/4615/7316/7335/3654/6233/51311/7311/7334/51284/7314 11 Myxoma_virus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 13/1217 21/10654 4.4667970151335436e-8 1.9445561564114932e-7 1.1380903683713883e-7 1147/4790/29110/8517/4615/7098/5970/4792/4793/1660/3661/3551/4791 13 Myxoma_virus R-HSA-76002 Platelet activation, signaling and aggregation 60/1217 262/10654 7.38767031440377e-8 3.20479219272727e-7 1.8756687047318692e-7 2788/151/2149/351/54331/59345/64805/2770/207/3959/7422/5594/10681/409/3082/51764/7277/94235/7534/5196/2769/3827/150/1950/55970/2792/346562/6714/152/1191/1432/6403/2793/4067/1893/3309/5880/2335/408/2785/2783/2784/2782/5478/2786/2771/5473/7076/3479/213/5660/801/9630/2791/2773/5595/2790/805/5054/2787 60 Myxoma_virus R-HSA-209560 NF-kB is activated and signals survival 10/1217 13/10654 7.555438843459007e-8 3.266070405312806e-7 1.911533003792953e-7 4790/8878/7316/5970/4792/3654/6233/7311/3551/7314 10 Myxoma_virus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 16/1217 32/10654 7.70619081208543e-8 3.3195898882829546e-7 1.942856351225072e-7 892/7027/54778/7316/1875/1024/4609/22938/4088/1874/4087/6233/1025/7311/7314/5054 16 Myxoma_virus R-HSA-193639 p75NTR signals via NF-kB 11/1217 16/10654 1.0486289746107132e-7 4.501431695889891e-7 2.6345528978849753e-7 4790/8878/4615/7316/5970/4792/3654/6233/7311/3551/7314 11 Myxoma_virus R-HSA-69618 Mitotic Spindle Checkpoint 33/1217 112/10654 1.6610532860266785e-7 7.10561683466968e-7 4.1587043162583146e-7 5903/11065/54908/246184/5525/7321/991/5526/8697/6232/8881/5528/5501/8655/51433/5519/1062/119504/5529/51529/7324/64682/29945/10393/5527/51434/5518/25906/5347/29882/996/5515/5516 33 Myxoma_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 16/1217 34/10654 2.2602778800533556e-7 9.635509855452365e-7 5.639374787239295e-7 7321/29110/7323/7316/3093/7322/7128/83737/3661/9246/51191/6233/7311/7318/5094/7314 16 Myxoma_virus R-HSA-5696394 DNA Damage Recognition in GG-NER 17/1217 38/10654 2.3659636760370295e-7 1.005126637544007e-6 5.882704602850691e-7 9318/7316/9978/64708/10980/1642/10920/10987/6233/2873/7311/60/8533/50813/7314/51138/8451 17 Myxoma_virus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 11/1217 17/10654 2.663659898369149e-7 1.1200098958330347e-6 6.555081840786302e-7 1147/4790/8517/4615/7098/5970/4792/4793/1660/3551/4791 11 Myxoma_virus R-HSA-432142 Platelet sensitization by LDL 11/1217 17/10654 2.663659898369149e-7 1.1200098958330347e-6 6.555081840786302e-7 5525/5526/2268/5528/5519/1432/5529/5527/5518/5515/5516 11 Myxoma_virus R-HSA-450513 Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA 11/1217 17/10654 2.663659898369149e-7 1.1200098958330347e-6 6.555081840786302e-7 5393/23404/51013/11340/51010/56915/23016/54512/118460/167227/22894 11 Myxoma_virus R-HSA-1296065 Inwardly rectifying K+ channels 15/1217 31/10654 3.433727832838866e-7 1.434017861036435e-6 8.392876237268949e-7 2788/54331/2550/94235/55970/9568/2792/2793/2785/2783/2784/2782/2786/2790/2787 15 Myxoma_virus R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 15/1217 31/10654 3.433727832838866e-7 1.434017861036435e-6 8.392876237268949e-7 1499/5525/139285/5526/1452/5528/5519/2932/324/8312/5529/5527/5518/5515/5516 15 Myxoma_virus R-HSA-3371511 HSF1 activation 9/1217 12/10654 5.1381909046551e-7 2.138598376532123e-6 1.2516574572150582e-6 6118/7531/1915/10013/7415/6119/3320/3326/6117 9 Myxoma_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 15/1217 32/10654 5.783529672512685e-7 2.3910431397770565e-6 1.3994058020738926e-6 57154/10273/4738/64750/7316/5501/23327/4088/9040/4087/5499/6233/7048/7311/7314 15 Myxoma_virus R-HSA-5673000 RAF activation 15/1217 32/10654 5.783529672512685e-7 2.3910431397770565e-6 1.3994058020738926e-6 5525/5526/5528/8315/6714/5519/3717/5529/5527/5518/3265/801/805/5515/5516 15 Myxoma_virus R-HSA-5675221 Negative regulation of MAPK pathway 17/1217 40/10654 5.832566488581553e-7 2.4032514762315963e-6 1.4065509750671938e-6 5525/5526/5594/5528/7316/8315/5519/5529/6233/5527/7311/5518/3265/7314/5595/5515/5516 17 Myxoma_virus R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 11/1217 18/10654 6.141185287018186e-7 2.521980091202135e-6 1.476039270739459e-6 7027/5934/891/983/6790/5111/2033/1874/7157/10498/3276 11 Myxoma_virus R-HSA-937039 IRAK1 recruits IKK complex 10/1217 15/10654 6.386460053818109e-7 2.6053373464582487e-6 1.5248257709534352e-6 1147/8517/7316/7335/3654/6233/7311/7334/3551/7314 10 Myxoma_virus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 10/1217 15/10654 6.386460053818109e-7 2.6053373464582487e-6 1.5248257709534352e-6 1147/8517/7316/7335/3654/6233/7311/7334/3551/7314 10 Myxoma_virus R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 13/1217 25/10654 7.340368269645685e-7 2.974780825066935e-6 1.7410499531534955e-6 2648/55534/3280/84441/10046/6772/22938/8850/1387/2033/9794/3516/4851 13 Myxoma_virus R-HSA-937041 IKK complex recruitment mediated by RIP1 13/1217 25/10654 7.340368269645685e-7 2.974780825066935e-6 1.7410499531534955e-6 1147/7321/7099/8517/7323/7316/7335/7322/6233/7311/7334/3551/7314 13 Myxoma_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 22/1217 63/10654 7.974978656693735e-7 3.221368427884158e-6 1.8853702777688383e-6 1147/6737/4790/1499/29110/8517/4615/7098/7316/5970/4792/4793/1387/2033/22954/1660/3661/6233/7311/3551/4791/7314 22 Myxoma_virus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 20/1217 54/10654 8.592338794992304e-7 3.4593991488335026e-6 2.024682516191857e-6 9318/27339/5430/7316/9978/64708/10980/1642/10920/2033/10987/6233/2873/7311/8533/7874/50813/7314/51138/8451 20 Myxoma_virus R-HSA-8863795 Downregulation of ERBB2 signaling 14/1217 29/10654 8.824399473630529e-7 3.5412573783429353e-6 2.07259168161732e-6 8065/10273/207/10193/2064/7316/1950/10000/3320/208/6233/7311/1956/7314 14 Myxoma_virus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 26/1217 84/10654 1.1890675622489267e-6 4.756270248995707e-6 2.7837022561193265e-6 9318/6118/7336/54778/7316/9978/64708/5111/10980/6119/1642/10920/10987/7329/6233/2873/7311/60/8533/6117/7334/5424/50813/7314/51138/8451 26 Myxoma_virus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 25/1217 79/10654 1.201541996707247e-6 4.79061404512404e-6 2.8038026494446067e-6 9318/6118/27339/5430/7316/9978/64708/5111/10980/6119/1642/10920/2033/10987/6233/2873/7311/8533/6117/7874/5424/50813/7314/51138/8451 25 Myxoma_virus R-HSA-163615 PKA activation 11/1217 19/10654 1.3078416852800495e-6 5.197615987951681e-6 3.0420086737413714e-6 112/114/108/113/111/107/196883/115/801/109/805 11 Myxoma_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 13/1217 26/10654 1.3148738219620515e-6 5.208760606614943e-6 3.0485312846302434e-6 57154/10273/64750/7316/5501/23327/4088/4087/5499/6233/7048/7311/7314 13 Myxoma_virus R-HSA-9614085 FOXO-mediated transcription 22/1217 65/10654 1.4660351632123118e-6 5.788959362428103e-6 3.3881042064791958e-6 207/1027/7295/4287/1649/7534/5934/694/114907/5443/1026/84676/8850/9314/1387/4088/10000/2033/4852/3630/4087/208 22 Myxoma_virus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 14/1217 30/10654 1.4812621030718786e-6 5.83039907662797e-6 3.4123576277257e-6 6118/7320/7316/9978/5111/6119/1642/6233/7311/6117/5424/7314/51514/8451 14 Myxoma_virus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 9/1217 13/10654 1.4999146700350812e-6 5.8850155206471975e-6 3.4443229935435157e-6 207/10193/2064/7316/10000/208/6233/7311/7314 9 Myxoma_virus R-HSA-1295596 Spry regulation of FGF signaling 10/1217 16/10654 1.5282845185830445e-6 5.958375085108578e-6 3.4872581453343956e-6 5594/7316/6714/6233/7311/5518/7314/5595/5515/5516 10 Myxoma_virus R-HSA-429958 mRNA decay by 3' to 5' exoribonuclease 10/1217 16/10654 1.5282845185830445e-6 5.958375085108578e-6 3.4872581453343956e-6 5393/23404/51013/11340/51010/56915/23016/54512/118460/22894 10 Myxoma_virus R-HSA-416476 G alpha (q) signalling events 49/1217 217/10654 1.7882381591699753e-6 6.949871962452396e-6 4.067551515960263e-6 2788/10316/2149/351/54331/59345/23566/2358/6863/84539/5594/846/10681/51764/94235/301/2769/3827/56923/55970/4314/2792/2840/5367/2793/2785/2783/624/2784/2829/2782/6288/185/2786/183/2847/57121/9170/1956/10874/3265/9630/1902/129521/2791/5595/2790/2787/623 49 Myxoma_virus R-HSA-9006931 Signaling by Nuclear Receptors 62/1217 299/10654 1.7941055939229516e-6 6.9507487160788566e-6 4.0680646535492285e-6 2788/27161/3725/3838/54331/59345/5430/2770/207/1903/5594/1027/10681/1737/51764/94235/4318/200845/4313/1950/55970/1655/4314/2792/346562/6714/2099/4609/8850/1387/2793/10000/3320/2033/2785/595/2783/2784/8312/2782/9682/2786/23112/2771/208/10498/3326/1025/2353/1956/6258/3276/3265/801/29116/2791/2773/5595/2790/805/2787/6387 62 Myxoma_virus R-HSA-73893 DNA Damage Bypass 18/1217 48/10654 2.4555686512024232e-6 9.483575480505911e-6 5.550452156652896e-6 6118/7320/7316/9978/5111/7415/6119/1642/25898/9246/6233/7311/7318/6117/5424/7314/51514/8451 18 Myxoma_virus R-HSA-168638 NOD1/2 Signaling Pathway 15/1217 36/10654 3.651216442519968e-6 1.4057183303701878e-5 8.227247576072954e-6 1147/834/8517/7316/7335/7128/1432/83737/3654/6233/7311/5600/7334/3551/7314 15 Myxoma_virus R-HSA-198323 AKT phosphorylates targets in the cytosol 9/1217 14/10654 3.7727069795367566e-6 1.4390015476127815e-5 8.422044259353686e-6 1147/207/1027/1026/2932/10000/208/23608/4193 9 Myxoma_virus R-HSA-419408 Lysosphingolipid and LPA receptors 9/1217 14/10654 3.7727069795367566e-6 1.4390015476127815e-5 8.422044259353686e-6 9294/23566/1903/53637/1901/57121/9170/8698/1902 9 Myxoma_virus R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 9/1217 14/10654 3.7727069795367566e-6 1.4390015476127815e-5 8.422044259353686e-6 1017/9134/1027/898/1869/890/1026/7157/8900 9 Myxoma_virus R-HSA-69205 G1/S-Specific Transcription 13/1217 28/10654 3.7980020527159225e-6 1.4441785583166718e-5 8.452343749546482e-6 26271/7027/898/5934/1869/1875/983/5111/4998/990/1874/81620/8900 13 Myxoma_virus R-HSA-5696398 Nucleotide Excision Repair 30/1217 111/10654 4.365015975692534e-6 1.6546768252471392e-5 9.684326942022304e-6 9318/6118/27339/5430/7336/54778/7316/9978/64708/5111/10980/6119/1642/10920/2033/10987/7329/6233/2873/7311/60/8533/6117/7334/7874/5424/50813/7314/51138/8451 30 Myxoma_virus R-HSA-111931 PKA-mediated phosphorylation of CREB 11/1217 21/10654 4.908679337311808e-6 1.8550591851436035e-5 1.0857104766091665e-5 112/114/108/113/111/107/196883/115/801/109/805 11 Myxoma_virus R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission 46/1217 206/10654 5.064608726306807e-6 1.9081339299113107e-5 1.1167735321165822e-5 2788/3838/54331/59345/2770/2550/10382/5594/10681/51764/112/7277/94235/114/108/113/55970/111/107/9568/2792/346562/6714/2793/2785/2783/2784/2782/81027/2786/2771/10383/84790/196883/115/3265/801/2791/2560/109/2773/5595/4193/2790/805/2787 46 Myxoma_virus R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 12/1217 25/10654 5.857452943004617e-6 2.2001164712749047e-5 1.2876621521046736e-5 1017/994/891/993/890/983/5519/8900/5518/5347/5515/5516 12 Myxoma_virus R-HSA-186712 Regulation of beta-cell development 16/1217 42/10654 7.006438242871887e-6 2.6157369440055046e-5 1.5309123433388336e-5 2648/207/55534/3280/84441/10046/22938/8850/1387/10000/2033/3630/208/9794/3516/4851 16 Myxoma_virus R-HSA-375280 Amine ligand-binding receptors 16/1217 42/10654 7.006438242871887e-6 2.6157369440055046e-5 1.5309123433388336e-5 151/3352/3354/150/3361/152/1129/3355/3351/11255/1132/1814/1815/3350/59340/1813 16 Myxoma_virus R-HSA-5633007 Regulation of TP53 Activity 38/1217 160/10654 7.392555461719707e-6 2.751549344060024e-5 1.6103992657904278e-5 1017/6118/9891/207/6749/11200/79813/7316/28996/890/80196/983/6790/8148/5519/6119/1432/10000/2033/1111/7157/8900/5371/208/6233/5527/7311/7161/5518/6117/5600/7874/10919/7314/253260/4193/5515/5516 38 Myxoma_virus R-HSA-9613829 Chaperone Mediated Autophagy 11/1217 22/10654 8.805609662053676e-6 3.2676238264006415e-5 1.9124421745424122e-5 1915/1080/10013/7316/3320/6233/3326/7311/7431/3312/7314 11 Myxoma_virus R-HSA-5654738 Signaling by FGFR2 22/1217 73/10654 1.2570521619687024e-5 4.6507155061424665e-5 2.7219242324911054e-5 5430/5594/3178/4686/7316/3185/6714/4670/2247/7072/6233/3187/7073/7311/5518/3265/22916/5725/7314/5595/5515/5516 22 Myxoma_virus R-HSA-110320 Translesion Synthesis by POLH 10/1217 19/10654 1.2748622061248626e-5 4.688448471480092e-5 2.7440082048563424e-5 6118/7316/5111/7415/6119/25898/6233/7311/6117/7314 10 Myxoma_virus R-HSA-6804760 Regulation of TP53 Activity through Methylation 10/1217 19/10654 1.2748622061248626e-5 4.688448471480092e-5 2.7440082048563424e-5 11200/79813/7316/2033/7157/6233/7311/10919/7314/4193 10 Myxoma_virus R-HSA-3371556 Cellular response to heat stress 25/1217 89/10654 1.3021127721226335e-5 4.774413497782989e-5 2.7943209552130456e-5 3303/6118/5903/7531/1915/5594/9530/3308/10013/3313/3305/7415/6119/2932/1387/3310/3309/3320/2033/3326/6117/3304/3312/8480/5595 25 Myxoma_virus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 11/1217 23/10654 1.5139587553500667e-5 5.5347097524963864e-5 3.239299539012324e-5 7321/64750/7323/54778/7316/23327/4088/4087/6233/7311/7314 11 Myxoma_virus R-HSA-8848021 Signaling by PTK6 18/1217 54/10654 1.6654952964016435e-5 6.052773466568805e-5 3.542506685406384e-5 1017/1019/207/9021/1027/898/202559/2064/1793/7316/1950/6774/595/6233/7311/1956/3265/7314 18 Myxoma_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 18/1217 54/10654 1.6654952964016435e-5 6.052773466568805e-5 3.542506685406384e-5 1017/1019/207/9021/1027/898/202559/2064/1793/7316/1950/6774/595/6233/7311/1956/3265/7314 18 Myxoma_virus R-HSA-9006936 Signaling by TGF-beta family members 27/1217 102/10654 1.9613166404145783e-5 7.106888532325766e-5 4.1594486027368e-5 57154/892/7027/7321/10273/4738/64750/7323/54778/7316/1875/5501/1024/4609/22938/23327/4088/1874/9040/4087/5499/6233/7048/1025/7311/7314/5054 27 Myxoma_virus R-HSA-400253 Circadian Clock 21/1217 70/10654 2.1284884392539018e-5 7.690022748272161e-5 4.500739561317867e-5 8454/5187/26224/8945/5936/10135/1407/6500/1408/406/7316/5501/1387/2033/5499/10498/6233/7311/8864/7314/5054 21 Myxoma_virus R-HSA-209543 p75NTR recruits signalling complexes 8/1217 13/10654 2.1503870803539927e-5 7.746423634491575e-5 4.533749307609988e-5 8878/4615/7316/3654/6233/7311/3551/7314 8 Myxoma_virus R-HSA-450341 Activation of the AP-1 family of transcription factors 7/1217 10/10654 2.191560527460053e-5 7.871727608836109e-5 4.607085963818126e-5 3725/5594/1432/2353/5599/5600/5595 7 Myxoma_virus R-HSA-350054 Notch-HLH transcription pathway 12/1217 28/10654 2.468752062684642e-5 8.841577154731043e-5 5.174709800914871e-5 2648/55534/84441/10013/10046/22938/8850/1387/4855/9794/3516/4851 12 Myxoma_virus R-HSA-199418 Negative regulation of the PI3K/AKT network 28/1217 110/10654 3.0312493174968576e-5 1.0824635243930808e-4 6.335334195226079e-5 3667/90865/5525/5526/207/5594/3082/2064/4615/5528/1950/6714/2099/5519/2247/5880/10000/5529/3630/3654/208/5527/5518/1956/940/5595/5515/5516 28 Myxoma_virus R-HSA-164378 PKA activation in glucagon signalling 9/1217 17/10654 3.323555450514509e-5 1.1834162760213512e-4 6.926180357780467e-5 112/114/108/113/111/107/196883/115/109 9 Myxoma_virus R-HSA-2559585 Oncogene Induced Senescence 13/1217 33/10654 3.357240141417162e-5 1.1919653758576207e-4 6.976215673807845e-5 1019/7027/5594/7316/1869/1021/7157/23112/6233/7311/7314/5595/4193 13 Myxoma_virus R-HSA-73856 RNA Polymerase II Transcription Termination 20/1217 67/10654 3.604265266307646e-5 1.2759927609456954e-4 7.468002744769322e-5 10921/6635/6432/6431/6430/7884/6428/8106/6637/4686/11338/7307/6429/10189/6634/9775/6427/6426/22916/6628 20 Myxoma_virus R-HSA-72165 mRNA Splicing - Minor Pathway 17/1217 52/10654 3.786031559472079e-5 1.3365016851775362e-4 7.822143321485068e-5 23451/6635/6633/6432/6431/6632/5430/4904/6637/23450/4686/6634/6427/6426/22916/10262/6628 17 Myxoma_virus R-HSA-3371568 Attenuation phase 8/1217 14/10654 4.514542256887751e-5 1.5891188744244884e-4 9.300635927723636e-5 3303/3305/1387/3320/2033/3326/3304/3312 8 Myxoma_virus R-HSA-77588 SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs 7/1217 11/10654 5.4305441594186236e-5 1.906105528320155e-4 1.1155863695311912e-4 6635/7884/6637/4686/6634/22916/6628 7 Myxoma_virus R-HSA-112043 PLC beta mediated events 17/1217 54/10654 6.514039720313203e-5 2.279913902109621e-4 1.3343651939038708e-4 3838/2770/5594/112/114/108/113/111/107/346562/2771/196883/115/801/109/2773/805 17 Myxoma_virus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 26/1217 103/10654 6.710856500004224e-5 2.342145951276262e-4 1.370787744894258e-4 3667/90865/5525/5526/207/5594/3082/2064/4615/5528/1950/6714/2099/5519/2247/5880/5529/3630/3654/5527/5518/1956/940/5595/5515/5516 26 Myxoma_virus R-HSA-388841 Costimulation by the CD28 family 20/1217 70/10654 7.196567869047443e-5 2.5045682527306357e-4 1.4658486441562592e-4 1326/5525/5526/207/5528/9020/6714/5519/29126/4067/10000/5529/208/5527/5518/1493/940/253260/5515/5516 20 Myxoma_virus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 12/1217 31/10654 8.257567403559188e-5 2.8657248003337803e-4 1.677222734303349e-4 3725/5594/5528/5519/1432/2353/5518/5599/5600/5595/5515/5516 12 Myxoma_virus R-HSA-112040 G-protein mediated events 17/1217 55/10654 8.43756851609546e-5 2.919967531412811e-4 1.7089693771512096e-4 3838/2770/5594/112/114/108/113/111/107/346562/2771/196883/115/801/109/2773/805 17 Myxoma_virus R-HSA-1227986 Signaling by ERBB2 16/1217 50/10654 8.531464172080959e-5 2.9441915574240175e-4 1.7231469726892103e-4 8065/10273/207/10193/2064/7316/1950/6714/10000/3320/208/6233/7311/1956/3265/7314 16 Myxoma_virus R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 8/1217 15/10654 8.705585014385812e-5 2.987543380981426e-4 1.7485194941663337e-4 6737/29110/7316/22954/3661/6233/7311/7314 8 Myxoma_virus R-HSA-844456 The NLRP3 inflammasome 8/1217 15/10654 8.705585014385812e-5 2.987543380981426e-4 1.7485194941663337e-4 834/351/4790/7295/5970/3326/114548/4791 8 Myxoma_virus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 23/1217 88/10654 9.811470049395217e-5 3.3577030835708075e-4 1.9651628607706795e-4 8454/8945/7531/4659/203068/10382/6500/7277/7316/891/8655/983/6790/10121/23291/3320/79866/6233/7311/5518/10383/5347/7314 23 Myxoma_virus R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 9/1217 19/10654 1.0203974572402347e-4 3.482353649085787e-4 2.0381170963976116e-4 7027/5934/1869/1875/993/5111/4609/990/1874 9 Myxoma_virus R-HSA-381119 Unfolded Protein Response (UPR) 24/1217 94/10654 1.0418273511885054e-4 3.545666565370825e-4 2.0751722464789948e-4 5393/23404/84699/5073/7184/5526/1051/1649/3576/468/10130/3309/51013/6347/11340/51010/56915/8570/23016/54512/118460/167227/9820/22894 24 Myxoma_virus R-HSA-1169408 ISG15 antiviral mechanism 20/1217 72/10654 1.1093828406988343e-4 3.7651781260081654e-4 2.20364577607279e-4 3838/5903/25820/7316/4734/6772/1973/3661/7324/3836/9246/51191/6233/7311/7318/9775/7334/8480/7314/5595 20 Myxoma_virus R-HSA-2197563 NOTCH2 intracellular domain regulates transcription 7/1217 12/10654 1.1746181829303391e-4 3.9647386338908977e-4 2.3204425531572672e-4 55534/3280/84441/10046/2033/9794/3516 7 Myxoma_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 7/1217 12/10654 1.1746181829303391e-4 3.9647386338908977e-4 2.3204425531572672e-4 29110/7098/7316/3661/6233/7311/7314 7 Myxoma_virus R-HSA-110312 Translesion synthesis by REV1 8/1217 16/10654 1.5670795537556513e-4 5.274978170019024e-4 3.087286437511134e-4 6118/7316/5111/6119/6233/7311/6117/7314 8 Myxoma_virus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 10/1217 24/10654 1.5805249989678057e-4 5.276983194385736e-4 3.088459918108535e-4 8517/7316/7335/1432/3654/6233/7311/5600/7334/7314 10 Myxoma_virus R-HSA-933542 TRAF6 mediated NF-kB activation 10/1217 24/10654 1.5805249989678057e-4 5.276983194385736e-4 3.088459918108535e-4 1147/351/4790/8517/5970/4792/4793/6288/3551/4791 10 Myxoma_virus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 10/1217 24/10654 1.5805249989678057e-4 5.276983194385736e-4 3.088459918108535e-4 207/5594/1027/1950/10000/595/208/2353/1956/5595 10 Myxoma_virus R-HSA-3700989 Transcriptional Regulation by TP53 65/1217 365/10654 1.5981340704741926e-4 5.321354526551907e-4 3.114429127382139e-4 1017/834/6118/27161/3725/9891/9134/7531/7027/5430/207/7832/1027/4869/898/7295/6749/11200/79813/7534/7001/5934/7316/1869/891/28996/890/80196/983/1026/6790/5111/8148/5519/6119/1432/1387/10000/2033/1874/1111/7157/8900/5371/23112/208/10498/6233/5527/1025/2353/7311/7161/5518/6117/5600/3276/7874/5052/10919/7314/253260/4193/5515/5516 65 Myxoma_virus R-HSA-622312 Inflammasomes 9/1217 20/10654 1.667978497965186e-4 5.531637761606337e-4 3.2375015949251027e-4 834/351/4790/7295/5970/598/3326/114548/4791 9 Myxoma_virus R-HSA-1980145 Signaling by NOTCH2 12/1217 33/10654 1.6702672461993157e-4 5.531637761606337e-4 3.2375015949251027e-4 142678/55534/3280/84441/10046/7316/2033/9794/6233/7311/3516/7314 12 Myxoma_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 21/1217 80/10654 1.8197070929074194e-4 6.010399835018607e-4 3.5177066703586356e-4 201626/3838/5903/25820/7316/4734/6772/1973/3661/7324/3836/9246/51191/6233/7311/7318/9775/7334/8480/7314/5595 21 Myxoma_virus R-HSA-111996 Ca-dependent events 13/1217 38/10654 1.8352569509025394e-4 6.02943083603181e-4 3.5288449441915495e-4 3838/5594/112/114/108/113/111/107/196883/115/801/109/805 13 Myxoma_virus R-HSA-5689896 Ovarian tumor domain proteases 13/1217 38/10654 1.8352569509025394e-4 6.02943083603181e-4 3.5288449441915495e-4 7321/8517/7316/79155/983/2099/7415/7128/324/7157/6233/7311/7314 13 Myxoma_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 16/1217 53/10654 1.846083404203705e-4 6.0488690265398e-4 3.5402215338172963e-4 7531/7027/207/5594/7534/1869/8655/6774/598/10000/708/7157/208/7161/5599/5595 16 Myxoma_virus R-HSA-5696395 Formation of Incision Complex in GG-NER 14/1217 43/10654 1.9066052289107998e-4 6.230603824981712e-4 3.6465854580591876e-4 6118/7336/54778/7316/9978/6119/1642/7329/6233/7311/6117/7334/7314/8451 14 Myxoma_virus R-HSA-5654732 Negative regulation of FGFR3 signaling 11/1217 29/10654 2.0228027181577144e-4 6.592838488810328e-4 3.85859053728219e-4 5594/7316/6714/2247/6233/7311/5518/7314/5595/5515/5516 11 Myxoma_virus R-HSA-202670 ERKs are inactivated 7/1217 13/10654 2.2941275703077725e-4 7.457427880261677e-4 4.364608764507219e-4 5594/5528/5519/5518/5595/5515/5516 7 Myxoma_virus R-HSA-190236 Signaling by FGFR 22/1217 87/10654 2.316652516538519e-4 7.510831316777514e-4 4.395864193431817e-4 5430/5594/3178/4686/7316/3185/6714/4670/2247/7072/6233/3187/7073/7311/5518/3265/22916/5725/7314/5595/5515/5516 22 Myxoma_virus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 13/1217 39/10654 2.4682097320670796e-4 7.981192624426883e-4 4.6711525527447147e-4 6118/7316/5111/7415/6119/25898/9246/6233/7311/7318/6117/5424/7314 13 Myxoma_virus R-HSA-5655862 Translesion synthesis by POLK 8/1217 17/10654 2.6646120059371726e-4 8.548963519048429e-4 5.003451820359e-4 6118/7316/5111/6119/6233/7311/6117/7314 8 Myxoma_virus R-HSA-5656121 Translesion synthesis by POLI 8/1217 17/10654 2.6646120059371726e-4 8.548963519048429e-4 5.003451820359e-4 6118/7316/5111/6119/6233/7311/6117/7314 8 Myxoma_virus R-HSA-8934593 Regulation of RUNX1 Expression and Activity 8/1217 17/10654 2.6646120059371726e-4 8.548963519048429e-4 5.003451820359e-4 27161/894/6714/1021/595/896/5371/23112 8 Myxoma_virus R-HSA-114452 Activation of BH3-only proteins 11/1217 30/10654 2.867171130902037e-4 9.15117832453707e-4 5.355910075451037e-4 7531/7027/207/7534/1869/8655/10000/7157/208/7161/5599 11 Myxoma_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 11/1217 30/10654 2.867171130902037e-4 9.15117832453707e-4 5.355910075451037e-4 7124/1147/8517/7316/7128/10616/6233/7311/3551/7185/7314 11 Myxoma_virus R-HSA-111367 SLBP independent Processing of Histone Pre-mRNAs 6/1217 10/10654 3.0660381153857274e-4 9.735461232358804e-4 5.697873328918133e-4 6635/6637/4686/6634/22916/6628 6 Myxoma_virus R-HSA-2465910 MASTL Facilitates Mitotic Progression 6/1217 10/10654 3.0660381153857274e-4 9.735461232358804e-4 5.697873328918133e-4 891/983/5519/5518/5515/5516 6 Myxoma_virus R-HSA-6803529 FGFR2 alternative splicing 10/1217 26/10654 3.4548491245923806e-4 0.0010941835787912117 6.403928156800922e-4 5430/3178/4686/3185/4670/7072/3187/7073/22916/5725 10 Myxoma_virus R-HSA-5654733 Negative regulation of FGFR4 signaling 11/1217 31/10654 3.989949045702391e-4 0.0012554238841739076 7.347619281093018e-4 5594/7316/6714/2247/6233/7311/5518/7314/5595/5515/5516 11 Myxoma_virus R-HSA-113510 E2F mediated regulation of DNA replication 9/1217 22/10654 3.9945305405533424e-4 0.0012554238841739076 7.347619281093018e-4 7027/1869/891/983/5519/4998/5518/5515/5516 9 Myxoma_virus R-HSA-198753 ERK/MAPK targets 9/1217 22/10654 3.9945305405533424e-4 0.0012554238841739076 7.347619281093018e-4 5594/5528/5519/1432/5518/5600/5595/5515/5516 9 Myxoma_virus R-HSA-111933 Calmodulin induced events 12/1217 36/10654 4.254775871710057e-4 0.0013304273791743123 7.786592231155196e-4 3838/112/114/108/113/111/107/196883/115/801/109/805 12 Myxoma_virus R-HSA-111997 CaM pathway 12/1217 36/10654 4.254775871710057e-4 0.0013304273791743123 7.786592231155196e-4 3838/112/114/108/113/111/107/196883/115/801/109/805 12 Myxoma_virus R-HSA-5656169 Termination of translesion DNA synthesis 11/1217 32/10654 5.459219175357854e-4 0.0017027235503900954 9.965530006982358e-4 6118/7316/5111/6119/9246/6233/7311/7318/6117/5424/7314 11 Myxoma_virus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 18/1217 69/10654 5.585909845983567e-4 0.001737838618750443 0.0010171047965174757 3303/6118/5903/7531/5594/9530/3308/3313/3305/6119/2932/3310/3309/6117/3304/3312/8480/5595 18 Myxoma_virus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 9/1217 23/10654 5.902582058218443e-4 0.0018317332734823985 0.001072058520450652 8517/7316/7335/3654/6233/7311/5599/7334/7314 9 Myxoma_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 8/1217 19/10654 6.716860954436124e-4 0.0020739781192644874 0.0012138371596857262 7316/1950/3320/6233/7311/1956/3265/7314 8 Myxoma_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 8/1217 19/10654 6.716860954436124e-4 0.0020739781192644874 0.0012138371596857262 7316/1950/3320/6233/7311/1956/3265/7314 8 Myxoma_virus R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 16/1217 59/10654 7.041106698876343e-4 0.0021686608632539134 0.0012692521286132357 7319/7321/7320/79577/7336/7323/7316/5111/7415/7322/118424/7324/6233/7311/7334/7314 16 Myxoma_virus R-HSA-5357905 Regulation of TNFR1 signaling 11/1217 33/10654 7.353695139937107e-4 0.002253669754328984 0.0013190052817116833 7124/1147/8517/7316/7128/10616/6233/7311/3551/7185/7314 11 Myxoma_virus R-HSA-5654726 Negative regulation of FGFR1 signaling 11/1217 33/10654 7.353695139937107e-4 0.002253669754328984 0.0013190052817116833 5594/7316/6714/2247/6233/7311/5518/7314/5595/5515/5516 11 Myxoma_virus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 12/1217 38/10654 7.41154468936137e-4 0.002265762545234047 0.0013260828293620319 7422/4869/4839/2064/1026/2099/4609/3329/1387/2033/7329/1956 12 Myxoma_virus R-HSA-5654727 Negative regulation of FGFR2 signaling 11/1217 34/10654 9.763212829727065e-4 0.0029772965856989467 0.0017425223523613964 5594/7316/6714/2247/6233/7311/5518/7314/5595/5515/5516 11 Myxoma_virus R-HSA-390666 Serotonin receptors 6/1217 12/10654 0.0011012618926506388 0.003341760225974352 0.001955831984614176 3352/3354/3361/3355/3351/3350 6 Myxoma_virus R-HSA-5689877 Josephin domain DUBs 6/1217 12/10654 0.0011012618926506388 0.003341760225974352 0.001955831984614176 4287/7316/7415/6233/7311/7314 6 Myxoma_virus R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 7/1217 16/10654 0.001121629461681926 0.003386881119588561 0.0019822398897113504 7027/5934/1869/1875/890/983/1874 7 Myxoma_virus R-HSA-418038 Nucleotide-like (purinergic) receptors 7/1217 16/10654 0.001121629461681926 0.003386881119588561 0.0019822398897113504 64805/140/2840/134/5030/53829/9934 7 Myxoma_virus R-HSA-429914 Deadenylation-dependent mRNA decay 15/1217 56/10654 0.0011759613757859777 0.003542260183296637 0.0020731785932657184 5393/23404/5073/26986/1973/51013/11340/9775/51010/56915/23016/54512/118460/167227/22894 15 Myxoma_virus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 9/1217 25/10654 0.0011943622450968619 0.003562843307407588 0.0020852252781734435 5594/5528/5519/1432/5518/5600/5595/5515/5516 9 Myxoma_virus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 9/1217 25/10654 0.0011943622450968619 0.003562843307407588 0.0020852252781734435 1147/207/1027/1026/2932/10000/208/253260/4193 9 Myxoma_virus R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 9/1217 25/10654 0.0011943622450968619 0.003562843307407588 0.0020852252781734435 6118/7316/5111/6119/6233/7311/6117/5424/7314 9 Myxoma_virus R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus 9/1217 25/10654 0.0011943622450968619 0.003562843307407588 0.0020852252781734435 142678/4904/7316/1950/11060/6233/7311/1956/7314 9 Myxoma_virus R-HSA-5654741 Signaling by FGFR3 12/1217 40/10654 0.001232135711709452 0.003666645402961461 0.002145977529928743 5594/7316/6714/2247/6233/7311/5518/3265/7314/5595/5515/5516 12 Myxoma_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 21/1217 92/10654 0.0013528892192752515 0.004016287995535205 0.0023506128476944764 1017/6118/9891/6749/11200/7316/28996/890/6790/8148/6119/1432/1111/7157/8900/6233/7311/6117/5600/7314/4193 21 Myxoma_virus R-HSA-5654743 Signaling by FGFR4 12/1217 41/10654 0.0015638316092555255 0.00462024110935925 0.002704088482494093 5594/7316/6714/2247/6233/7311/5518/3265/7314/5595/5515/5516 12 Myxoma_virus R-HSA-5696400 Dual Incision in GG-NER 12/1217 41/10654 0.0015638316092555255 0.00462024110935925 0.002704088482494093 6118/7316/9978/5111/6119/1642/6233/7311/6117/5424/7314/8451 12 Myxoma_virus R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 23/1217 106/10654 0.0016901741702073174 0.004981565975347883 0.0029155610843415074 9318/4738/409/1080/7316/1950/8218/64708/10980/1129/10920/408/10987/185/6233/2873/7311/1213/1956/8533/50813/7314/51138 23 Newcastle_disease_virus R-HSA-68886 M Phase 257/528 395/10654 1.1607285162920775e-259 1.1108171900915181e-256 5.339351174943556e-257 114791/5716/8615/9491/5715/701/79959/10844/140609/54821/23198/79172/115106/7514/5519/10274/84131/5718/5861/81876/121441/7311/5711/9184/220134/9183/4926/5689/5905/55839/54930/147841/23244/7277/348995/11130/23421/79441/81565/5701/22995/55559/2491/5688/10112/143471/26271/79682/79023/55920/5706/9133/1062/5518/25906/699/5687/10381/57122/5705/79980/64105/10735/55844/10383/5684/5903/55835/54820/5116/5347/113130/57551/7846/23310/10197/10403/7840/54892/5720/5685/29922/6232/11065/7283/54908/332/5683/440145/23047/5698/84643/5708/3320/1780/22919/5692/8881/5686/9493/5713/9814/29882/653784/80097/6249/6396/1060/91687/55143/11258/10051/23122/5885/119504/5528/79003/9662/80184/55142/5682/5048/64151/8243/1781/22981/9126/23354/7316/10213/5709/246184/5694/10426/5699/80321/55055/23397/23332/25936/5525/891/84930/9735/1453/8636/7531/22897/5695/10142/80776/5501/5529/25909/27229/64689/1783/5710/1058/22994/64946/26003/5700/9793/11190/11064/51143/122706/7321/5707/57405/10726/9918/8655/5702/991/91754/401541/203068/10540/79019/5526/4085/5108/10733/9738/81930/51529/54801/55746/85378/8481/983/7532/5693/1639/5862/55125/1069/5721/7324/140735/1454/93323/5696/83540/8548/10592/348235/10806/55755/5719/64682/5691/2801/29945/29781/10393/80152/8697/5714/5690/4751/55722/10382/8480/9212/4957/11004/9232/1063/23279/55166/7314/5577/996/5704/10121/6233/9700/5527/51434/5515/1778/8379/95681/5717/51433/9861/3619/79902/27175/9702/5566/5516/80254/3796 257 Newcastle_disease_virus R-HSA-68877 Mitotic Prometaphase 172/528 200/10654 1.4359757280276047e-204 6.871143858612088e-202 3.3027441744634903e-202 114791/701/79959/10844/54821/79172/115106/7514/5519/10274/84131/121441/9184/220134/9183/4926/5905/55839/54930/147841/23244/7277/348995/11130/23421/79441/81565/22995/55559/2491/79682/79023/55920/9133/1062/5518/699/10381/57122/79980/64105/10735/10383/5903/55835/54820/5116/5347/113130/57551/7846/10403/7840/29922/6232/7283/54908/332/440145/23047/84643/3320/1780/22919/9814/653784/80097/6249/6396/1060/91687/55143/11258/10051/23122/5885/5528/79003/9662/80184/55142/5048/64151/8243/1781/22981/9126/23354/10426/80321/55055/23397/23332/25936/5525/891/9735/1453/8636/7531/22897/10142/80776/5501/5529/25909/27229/1783/1058/22994/64946/9793/11190/11064/51143/57405/10726/9918/8655/991/401541/203068/10540/79019/5526/4085/5108/10733/9738/81930/54801/55746/85378/8481/983/7532/1639/55125/1069/140735/1454/93323/83540/10592/348235/10806/55755/80152/4751/55722/10382/9212/4957/11004/1063/23279/55166/5577/10121/5527/5515/1778/8379/95681/3619/79902/27175/9702/5566/5516/80254/3796 172 Newcastle_disease_virus R-HSA-2467813 Separation of Sister Chromatids 166/528 190/10654 1.431529399651284e-199 4.566578784887596e-197 2.1950117461319688e-197 5716/9491/5715/701/54821/23198/79172/7514/5519/10274/5718/7311/5711/9184/220134/9183/5689/5905/55839/147841/23244/7277/348995/11130/23421/81565/5701/2491/5688/143471/79682/79023/55920/5706/1062/5518/25906/699/5687/10381/57122/5705/79980/64105/10735/10383/5684/5903/54820/5347/113130/57551/7846/10197/10403/5720/5685/6232/11065/54908/332/5683/23047/5698/84643/5708/1780/22919/5692/8881/5686/5713/29882/6249/6396/1060/91687/55143/23122/5885/119504/5528/79003/5682/5048/8243/1781/9126/7316/10213/5709/246184/5694/5699/55055/23332/25936/5525/9735/5695/80776/5501/5529/25909/1783/5710/1058/64946/5700/9793/51143/122706/7321/5707/57405/10726/8655/5702/991/401541/79019/5526/4085/81930/51529/55746/5693/5721/7324/140735/5696/83540/348235/5719/64682/5691/29945/10393/80152/8697/5714/5690/10382/9212/11004/9232/1063/23279/55166/7314/996/5704/6233/9700/5527/51434/5515/1778/8379/5717/51433/9861/3619/79902/5516/3796 166 Newcastle_disease_virus R-HSA-69275 G2/M Transition 166/528 196/10654 1.424391916234223e-194 3.4078576595903788e-192 1.6380507036693565e-192 114791/5716/9491/5715/79959/10844/8454/23198/6500/55957/115106/7514/5519/84131/5718/9088/121441/7311/5711/5689/5928/54930/7277/79441/8945/5701/22995/55559/5688/143471/5706/9133/5518/5687/10381/5705/91750/10133/10383/5684/55835/54820/5116/5347/994/23291/7846/10197/7840/5720/5685/29922/4605/286826/7283/5683/440145/5698/5708/3320/22919/5692/984/5686/5713/9814/2305/653784/80097/2033/995/11258/9662/80184/55142/5682/5048/1781/22981/23354/7316/10213/728642/5709/5694/10426/5699/80321/23332/891/1453/8636/7531/51512/22897/993/5695/10142/7465/27229/5710/890/22994/4659/5700/9793/11190/11064/122706/5707/4218/8655/5702/203068/10540/7157/5108/10733/9738/8900/54801/85378/8481/79866/983/7532/5693/84962/1639/55125/1069/5721/1454/93323/5696/132660/10806/55755/5719/6790/5691/5714/22974/5690/4751/55722/10382/3161/5500/4957/1063/7314/5577/5704/10121/6233/5515/1778/95681/5717/9861/27175/9702/5566/5516/80254 166 Newcastle_disease_virus R-HSA-453274 Mitotic G2-G2/M phases 166/528 198/10654 5.22200661472707e-193 9.994920660587612e-191 4.804246085548904e-191 114791/5716/9491/5715/79959/10844/8454/23198/6500/55957/115106/7514/5519/84131/5718/9088/121441/7311/5711/5689/5928/54930/7277/79441/8945/5701/22995/55559/5688/143471/5706/9133/5518/5687/10381/5705/91750/10133/10383/5684/55835/54820/5116/5347/994/23291/7846/10197/7840/5720/5685/29922/4605/286826/7283/5683/440145/5698/5708/3320/22919/5692/984/5686/5713/9814/2305/653784/80097/2033/995/11258/9662/80184/55142/5682/5048/1781/22981/23354/7316/10213/728642/5709/5694/10426/5699/80321/23332/891/1453/8636/7531/51512/22897/993/5695/10142/7465/27229/5710/890/22994/4659/5700/9793/11190/11064/122706/5707/4218/8655/5702/203068/10540/7157/5108/10733/9738/8900/54801/85378/8481/79866/983/7532/5693/84962/1639/55125/1069/5721/1454/93323/5696/132660/10806/55755/5719/6790/5691/5714/22974/5690/4751/55722/10382/3161/5500/4957/1063/7314/5577/5704/10121/6233/5515/1778/95681/5717/9861/27175/9702/5566/5516/80254 166 Newcastle_disease_virus R-HSA-2555396 Mitotic Metaphase and Anaphase 167/528 202/10654 4.011445961159821e-192 6.398256308049914e-190 3.0754419035558623e-190 5716/9491/5715/701/54821/23198/79172/7514/5519/10274/5718/7311/5711/9184/220134/9183/5689/5905/55839/147841/23244/7277/348995/11130/23421/81565/5701/2491/5688/143471/26271/79682/79023/55920/5706/1062/5518/25906/699/5687/10381/57122/5705/79980/64105/10735/10383/5684/5903/54820/5347/113130/57551/7846/10197/10403/5720/5685/6232/11065/54908/332/5683/23047/5698/84643/5708/1780/22919/5692/8881/5686/5713/29882/6249/6396/1060/91687/55143/23122/5885/119504/5528/79003/5682/5048/8243/1781/9126/7316/10213/5709/246184/5694/5699/55055/23332/25936/5525/9735/5695/80776/5501/5529/25909/1783/5710/1058/64946/5700/9793/51143/122706/7321/5707/57405/10726/8655/5702/991/401541/79019/5526/4085/81930/51529/55746/5693/5721/7324/140735/5696/83540/348235/5719/64682/5691/29945/10393/80152/8697/5714/5690/10382/9212/11004/9232/1063/23279/55166/7314/996/5704/6233/9700/5527/51434/5515/1778/8379/5717/51433/9861/3619/79902/5516/3796 167 Newcastle_disease_virus R-HSA-68882 Mitotic Anaphase 166/528 201/10654 9.57694568187796e-191 1.3093052882224583e-188 6.29342144809123e-189 5716/9491/5715/701/54821/23198/79172/7514/5519/10274/5718/7311/5711/9184/220134/9183/5689/5905/55839/147841/23244/7277/348995/11130/23421/81565/5701/2491/5688/143471/79682/79023/55920/5706/1062/5518/25906/699/5687/10381/57122/5705/79980/64105/10735/10383/5684/5903/54820/5347/113130/57551/7846/10197/10403/5720/5685/6232/11065/54908/332/5683/23047/5698/84643/5708/1780/22919/5692/8881/5686/5713/29882/6249/6396/1060/91687/55143/23122/5885/119504/5528/79003/5682/5048/8243/1781/9126/7316/10213/5709/246184/5694/5699/55055/23332/25936/5525/9735/5695/80776/5501/5529/25909/1783/5710/1058/64946/5700/9793/51143/122706/7321/5707/57405/10726/8655/5702/991/401541/79019/5526/4085/81930/51529/55746/5693/5721/7324/140735/5696/83540/348235/5719/64682/5691/29945/10393/80152/8697/5714/5690/10382/9212/11004/9232/1063/23279/55166/7314/996/5704/6233/9700/5527/51434/5515/1778/8379/5717/51433/9861/3619/79902/5516/3796 166 Newcastle_disease_virus R-HSA-69620 Cell Cycle Checkpoints 189/528 293/10654 2.118751929291412e-183 2.5345569954148513e-181 1.2182823593425616e-181 5716/9491/5715/701/672/54821/23198/63967/79172/7514/9656/5519/5932/5718/7158/23595/9088/7311/5711/9184/220134/9183/4172/5689/5905/55839/147841/348995/11130/23421/81565/5701/4173/2491/5688/11200/143471/79682/79023/55920/5706/9133/1062/5518/472/25906/699/5687/57122/5705/79980/64105/5684/5903/54820/5347/57551/10197/10403/5720/5685/6232/11065/7156/54908/332/5683/5698/84643/5708/8318/1780/22919/5692/8881/5686/990/5713/29882/11073/6249/6396/1060/91687/55143/29086/995/23122/119504/5528/79003/5682/9156/5048/1781/7316/10213/5709/246184/5694/5699/55055/23332/25936/5525/4174/891/9735/7531/51512/993/5695/80776/5501/5529/7465/4175/25909/1783/5710/1058/890/64946/5700/9793/51143/1111/122706/7321/5707/57405/10726/8655/5702/991/401541/79019/5526/7157/4085/81930/8900/51529/55746/983/7532/5693/8317/5721/7324/140735/5696/83540/348235/5719/641/64682/5691/29945/10393/80152/8697/5714/5690/4176/9212/11004/4171/1063/23279/55166/7314/996/5704/6233/5527/4193/51434/5515/1778/8379/5717/51433/55388/9861/3619/79902/5516/3796 189 Newcastle_disease_virus R-HSA-69618 Mitotic Spindle Checkpoint 103/528 112/10654 5.780348327362936e-127 6.146437054762589e-125 2.954400256207723e-125 701/54821/79172/7514/5519/9184/220134/9183/5905/55839/147841/348995/11130/23421/81565/2491/79682/79023/55920/1062/5518/25906/699/57122/79980/64105/5903/54820/5347/57551/10403/6232/11065/54908/332/84643/1780/22919/8881/29882/6249/6396/1060/91687/55143/23122/119504/5528/79003/5048/1781/246184/55055/23332/25936/5525/9735/80776/5501/5529/25909/1783/1058/64946/9793/51143/7321/57405/10726/8655/991/401541/79019/5526/4085/81930/51529/55746/7324/140735/83540/348235/64682/29945/10393/80152/8697/9212/11004/1063/23279/55166/996/5527/51434/5515/1778/8379/51433/3619/79902/5516/3796 103 Newcastle_disease_virus R-HSA-5620912 Anchoring of the basal body to the plasma membrane 95/528 98/10654 2.71341679086397e-123 2.596739868856819e-121 1.248171723797426e-121 79959/115106/132320/347240/57545/84131/121441/26005/54930/7277/79441/22995/55559/5518/79867/26123/10383/55835/54820/5116/5347/7846/7840/23322/7283/3320/22919/54806/9814/11258/9662/80184/55142/91147/5048/1781/22981/23354/80321/23332/8766/1453/8636/7531/22897/10142/54903/80776/22832/27077/22994/9793/11190/11064/4867/146057/4218/8655/79600/203068/10540/84902/5108/10733/9738/79598/261734/54801/8481/983/7532/1639/55125/1069/57787/1454/93323/10806/51259/55755/9657/4751/55722/10382/4957/117177/85302/5577/51134/10121/1778/95681/9702/5566/80254 95 Newcastle_disease_virus R-HSA-2500257 Resolution of Sister Chromatid Cohesion 103/528 126/10654 5.508470082232663e-115 4.792368971542417e-113 2.3035420343882044e-113 701/54821/79172/7514/5519/10274/9184/220134/9183/5905/55839/147841/23244/7277/348995/11130/23421/81565/2491/79682/79023/55920/9133/1062/5518/699/10381/57122/79980/64105/10735/10383/5903/54820/5347/113130/57551/7846/10403/6232/54908/332/23047/84643/1780/22919/6249/6396/1060/91687/55143/23122/5885/5528/79003/5048/8243/1781/9126/55055/23332/25936/5525/891/9735/80776/5501/5529/25909/1783/1058/64946/9793/51143/57405/10726/8655/991/401541/79019/5526/4085/81930/55746/983/140735/83540/348235/80152/10382/9212/11004/1063/23279/55166/5527/5515/1778/8379/3619/79902/5516/3796 103 Newcastle_disease_virus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 85/528 88/10654 1.2867180850374833e-109 1.026157672817393e-107 4.932419325977019e-108 79959/8454/6500/115106/84131/121441/7311/54930/7277/79441/8945/22995/55559/9133/5518/10133/10383/55835/54820/5116/5347/23291/7846/7840/7283/3320/22919/9814/11258/9662/80184/55142/5048/1781/22981/23354/7316/80321/23332/891/1453/8636/7531/22897/10142/22994/4659/9793/11190/11064/4218/8655/203068/10540/5108/10733/9738/54801/8481/79866/983/7532/84962/1639/55125/1069/1454/93323/10806/55755/6790/4751/55722/10382/5500/4957/7314/5577/10121/6233/1778/95681/9702/5566/80254 85 Newcastle_disease_virus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 83/528 86/10654 6.782660507113608e-107 4.636432932362659e-105 2.228588452337328e-105 5716/9491/5715/701/8454/23198/6500/5718/51343/7311/5711/9184/5689/8945/5701/5688/143471/26271/5706/25906/5687/5705/5684/5347/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/119504/5682/7316/10213/5709/246184/5694/5699/891/5695/5710/890/5700/122706/7321/5707/5702/991/4085/8900/51529/983/5693/8556/5721/7324/5696/5719/6790/64682/5691/29945/10393/8697/5714/5690/4751/9212/9232/7314/996/5704/6233/51434/5717/51433/9861 83 Newcastle_disease_virus R-HSA-453276 Regulation of mitotic cell cycle 83/528 86/10654 6.782660507113608e-107 4.636432932362659e-105 2.228588452337328e-105 5716/9491/5715/701/8454/23198/6500/5718/51343/7311/5711/9184/5689/8945/5701/5688/143471/26271/5706/25906/5687/5705/5684/5347/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/119504/5682/7316/10213/5709/246184/5694/5699/891/5695/5710/890/5700/122706/7321/5707/5702/991/4085/8900/51529/983/5693/8556/5721/7324/5696/5719/6790/64682/5691/29945/10393/8697/5714/5690/4751/9212/9232/7314/996/5704/6233/51434/5717/51433/9861 83 Newcastle_disease_virus R-HSA-141424 Amplification of signal from the kinetochores 87/528 96/10654 2.0706251214493398e-105 1.2384926507668863e-103 5.953047224166851e-104 701/54821/79172/7514/5519/9184/220134/9183/5905/55839/147841/348995/11130/23421/81565/2491/79682/79023/55920/1062/5518/699/57122/79980/64105/5903/54820/5347/57551/10403/6232/54908/332/84643/1780/22919/6249/6396/1060/91687/55143/23122/5528/79003/5048/1781/55055/23332/25936/5525/9735/80776/5501/5529/25909/1783/1058/64946/9793/51143/57405/10726/8655/991/401541/79019/5526/4085/81930/55746/140735/83540/348235/80152/9212/11004/1063/23279/55166/5527/5515/1778/8379/3619/79902/5516/3796 87 Newcastle_disease_virus R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 87/528 96/10654 2.0706251214493398e-105 1.2384926507668863e-103 5.953047224166851e-104 701/54821/79172/7514/5519/9184/220134/9183/5905/55839/147841/348995/11130/23421/81565/2491/79682/79023/55920/1062/5518/699/57122/79980/64105/5903/54820/5347/57551/10403/6232/54908/332/84643/1780/22919/6249/6396/1060/91687/55143/23122/5528/79003/5048/1781/55055/23332/25936/5525/9735/80776/5501/5529/25909/1783/1058/64946/9793/51143/57405/10726/8655/991/401541/79019/5526/4085/81930/55746/140735/83540/348235/80152/9212/11004/1063/23279/55166/5527/5515/1778/8379/3619/79902/5516/3796 87 Newcastle_disease_virus R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 80/528 82/10654 3.037565563941587e-104 1.614972358162277e-102 7.762667552295166e-103 114791/79959/10844/115106/84131/121441/54930/7277/79441/22995/55559/5518/10383/55835/54820/5116/5347/7846/7840/29922/7283/440145/3320/22919/984/9814/653784/80097/11258/9662/80184/55142/5048/1781/22981/23354/728642/10426/80321/23332/1453/8636/7531/22897/10142/27229/22994/9793/11190/11064/8655/203068/10540/5108/10733/9738/54801/85378/8481/983/7532/1639/55125/1069/1454/93323/10806/55755/4751/55722/10382/4957/5577/10121/1778/95681/27175/9702/5566/80254 80 Newcastle_disease_virus R-HSA-380287 Centrosome maturation 80/528 82/10654 3.037565563941587e-104 1.614972358162277e-102 7.762667552295166e-103 114791/79959/10844/115106/84131/121441/54930/7277/79441/22995/55559/5518/10383/55835/54820/5116/5347/7846/7840/29922/7283/440145/3320/22919/984/9814/653784/80097/11258/9662/80184/55142/5048/1781/22981/23354/728642/10426/80321/23332/1453/8636/7531/22897/10142/27229/22994/9793/11190/11064/8655/203068/10540/5108/10733/9738/54801/85378/8481/983/7532/1639/55125/1069/1454/93323/10806/55755/4751/55722/10382/4957/5577/10121/1778/95681/27175/9702/5566/80254 80 Newcastle_disease_virus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 78/528 80/10654 1.599325031948239e-101 8.055547660918236e-100 3.872050077348368e-100 5716/9491/5715/701/8454/23198/6500/5718/51343/7311/5711/9184/5689/8945/5701/5688/143471/26271/5706/25906/5687/5705/5684/5347/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/119504/5682/7316/10213/5709/246184/5694/5699/891/5695/5710/890/5700/122706/7321/5707/5702/991/4085/8900/51529/983/5693/5721/7324/5696/5719/64682/5691/29945/10393/8697/5714/5690/7314/996/5704/6233/51434/5717/51433/9861 78 Newcastle_disease_virus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 75/528 76/10654 5.145052747990889e-99 2.46190773991364e-97 1.1833621320379042e-97 5716/9491/5715/701/23198/5718/7311/5711/9184/5689/5701/5688/143471/5706/25906/5687/5705/5684/5347/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/119504/5682/7316/10213/5709/246184/5694/5699/891/5695/5710/890/5700/122706/7321/5707/5702/991/4085/8900/51529/983/5693/5721/7324/5696/5719/64682/5691/29945/10393/8697/5714/5690/4751/9232/7314/996/5704/6233/51434/5717/51433/9861 75 Newcastle_disease_virus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 74/528 75/10654 1.1831239476433964e-97 5.391664847117764e-96 2.591604837695059e-96 5716/9491/5715/701/23198/5718/7311/5711/9184/5689/5701/5688/143471/5706/25906/5687/5705/5684/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/119504/5682/7316/10213/5709/246184/5694/5699/891/5695/5710/890/5700/122706/7321/5707/5702/991/4085/8900/51529/983/5693/5721/7324/5696/5719/64682/5691/29945/10393/8697/5714/5690/4751/9232/7314/996/5704/6233/51434/5717/51433/9861 74 Newcastle_disease_virus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72/528 73/10654 6.213499495977085e-95 2.702872280750032e-93 1.299186258249754e-93 5716/9491/5715/701/23198/5718/7311/5711/9184/5689/5701/5688/143471/5706/25906/5687/5705/5684/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/119504/5682/7316/10213/5709/246184/5694/5699/5695/5710/890/5700/122706/7321/5707/5702/991/4085/8900/51529/983/5693/5721/7324/5696/5719/64682/5691/29945/10393/8697/5714/5690/4751/7314/996/5704/6233/51434/5717/51433/9861 72 Newcastle_disease_virus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 71/528 72/10654 1.4190633210124838e-93 5.904537383517161e-92 2.8381266420249677e-92 5716/9491/5715/701/23198/5718/7311/5711/9184/5689/5701/5688/143471/5706/25906/5687/5705/5684/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/119504/5682/7316/10213/5709/246184/5694/5699/5695/5710/890/5700/122706/7321/5707/5702/991/4085/8900/51529/983/5693/5721/7324/5696/5719/64682/5691/29945/10393/8697/5714/5690/7314/996/5704/6233/51434/5717/51433/9861 71 Newcastle_disease_virus R-HSA-8854518 AURKA Activation by TPX2 71/528 73/10654 4.9590018895886646e-092 1.97740200347348e-90 9.504753621711607e-91 79959/115106/84131/121441/54930/7277/79441/22995/55559/5518/10383/55835/54820/5116/5347/7846/7840/7283/3320/22919/9814/11258/9662/80184/55142/5048/1781/22981/23354/80321/23332/1453/8636/7531/22897/10142/22994/9793/11190/11064/8655/203068/10540/5108/10733/9738/54801/8481/983/7532/1639/55125/1069/1454/93323/10806/55755/6790/22974/4751/55722/10382/3161/4957/5577/10121/1778/95681/9702/5566/80254 71 Newcastle_disease_virus R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 80/528 94/10654 9.540642727527128e-92 3.652158036097385e-90 1.7554782618649914e-90 114791/79959/10844/115106/84131/121441/4926/54930/7277/79441/22995/55559/5518/10381/10383/55835/54820/5116/5347/7846/7840/29922/7283/440145/3320/22919/9814/653784/80097/11258/9662/80184/55142/5048/1781/22981/23354/10426/80321/23332/1453/8636/7531/22897/10142/27229/22994/9793/11190/11064/8655/203068/10540/5108/10733/9738/54801/85378/8481/983/7532/1639/55125/1069/1454/93323/10806/55755/4751/55722/10382/4957/5577/10121/1778/95681/27175/9702/5566/80254 80 Newcastle_disease_virus R-HSA-69052 Switching of origins to a post-replicative state 78/528 90/10654 9.022733770573845e-91 3.321060084015065e-89 1.5963298209476802e-89 5716/9491/5715/8454/23198/6500/5718/51343/23595/7311/5711/4172/5689/5701/4173/5688/143471/5706/25906/5687/5705/5684/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/990/5713/29882/119504/5682/7316/10213/5709/246184/5694/5699/4174/5695/4175/5710/890/5700/81620/122706/7321/5707/5702/8900/51529/5693/5721/7324/5696/5719/64682/5691/29945/10393/8697/5714/5690/4176/4171/7314/996/5704/6233/51434/5717/51433/9861 78 Newcastle_disease_virus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 70/528 72/10654 1.1143995259701564e-90 3.949927208716443e-89 1.898606599801007e-89 5716/9491/5715/23198/5718/51343/7311/5711/5689/5701/5688/143471/5706/25906/5687/5705/5684/5347/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/119504/5682/7316/10213/5709/246184/5694/5699/5695/5710/5700/122706/7321/5707/5702/991/51529/5693/5721/7324/5696/5719/6790/64682/5691/29945/10393/8697/5714/5690/9212/9232/7314/996/5704/6233/51434/5717/51433/9861 70 Newcastle_disease_virus R-HSA-5663220 RHO GTPases Activate Formins 94/528 140/10654 1.6316739782728934e-90 5.57682856145414e-89 2.6806072500197534e-89 701/54821/79172/7514/5519/9184/220134/9183/5905/55839/147841/7277/348995/11130/23421/81565/2491/79682/79023/55920/1062/5518/699/10381/57122/79980/64105/10383/5903/54820/5347/57551/7846/10403/6232/54908/332/84643/1780/22919/6249/6396/1060/91687/55143/23122/5528/79003/5048/1781/55055/23332/25936/5525/9735/80776/5501/5529/25909/1783/1058/64946/9793/51143/57405/10726/8655/991/1856/401541/79019/998/5526/4085/81930/55746/140735/83540/348235/80152/10382/9212/11004/1063/23279/55166/5527/5515/1778/8379/3619/79902/5516/3796 94 Newcastle_disease_virus R-HSA-69242 S Phase 99/528 161/10654 1.1336688729030326e-89 3.7411072805800074e-88 1.79823338460481e-88 5716/9491/5715/8454/23198/6500/55957/10274/5718/51343/23595/7311/5711/4172/5689/5928/23244/5701/4173/5688/143471/5706/25906/5687/5705/91750/10735/5684/994/113130/10197/5720/5685/11065/157570/286826/5683/23047/5698/5708/8318/5692/8881/5686/990/5713/29882/5885/119504/5682/8243/9126/7316/10213/5709/246184/5694/5699/4174/993/5695/7465/4175/1163/5710/890/5700/81620/122706/7321/5707/5702/8900/51529/5693/5721/7324/5696/132660/5719/64682/5691/29945/10393/8697/5714/5690/5111/4176/4171/4609/7314/996/5704/6233/51434/5717/51433/9861 99 Newcastle_disease_virus R-HSA-380259 Loss of Nlp from mitotic centrosomes 68/528 70/10654 5.586037418088908e-88 1.7244638093906724e-86 8.288958749422248e-87 79959/115106/84131/121441/54930/7277/79441/22995/55559/5518/10383/55835/54820/5116/5347/7846/7840/7283/3320/22919/9814/11258/9662/80184/55142/5048/1781/22981/23354/80321/23332/1453/8636/7531/22897/10142/22994/9793/11190/11064/8655/203068/10540/5108/10733/9738/54801/8481/983/7532/1639/55125/1069/1454/93323/10806/55755/4751/55722/10382/4957/5577/10121/1778/95681/9702/5566/80254 68 Newcastle_disease_virus R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 68/528 70/10654 5.586037418088908e-88 1.7244638093906724e-86 8.288958749422248e-87 79959/115106/84131/121441/54930/7277/79441/22995/55559/5518/10383/55835/54820/5116/5347/7846/7840/7283/3320/22919/9814/11258/9662/80184/55142/5048/1781/22981/23354/80321/23332/1453/8636/7531/22897/10142/22994/9793/11190/11064/8655/203068/10540/5108/10733/9738/54801/8481/983/7532/1639/55125/1069/1454/93323/10806/55755/4751/55722/10382/4957/5577/10121/1778/95681/9702/5566/80254 68 Newcastle_disease_virus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 66/528 67/10654 8.520066373551345e-87 2.548032349840199e-85 1.2247595411980057e-85 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/25906/5687/5705/5684/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/119504/5682/7316/10213/5709/246184/5694/5699/5695/5710/5700/122706/7321/5707/5702/991/51529/5693/5721/7324/5696/5719/64682/5691/29945/10393/8697/5714/5690/9232/7314/996/5704/6233/51434/5717/51433/9861 66 Newcastle_disease_virus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 68/528 72/10654 2.1801633978563166e-85 6.3224738537833185e-84 3.0390156454966836e-84 5716/9491/5715/23198/5718/51343/7311/5711/5689/5701/5688/143471/5706/25906/5687/5705/5684/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/990/5713/29882/119504/5682/7316/10213/5709/246184/5694/5699/5695/5710/890/5700/122706/7321/5707/5702/8900/51529/5693/5721/7324/5696/5719/64682/5691/29945/10393/8697/5714/5690/7314/996/5704/6233/51434/5717/51433/9861 68 Newcastle_disease_virus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 62/528 63/10654 2.1641839802422856e-81 6.0915413796819626e-80 2.9280136203277984e-80 5716/9491/5715/5718/51343/7311/5711/5689/5701/5688/5706/25906/5687/5705/5684/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/119504/5682/7316/10213/5709/246184/5694/5699/5695/5710/5700/7321/5707/5702/51529/5693/5721/7324/5696/5719/64682/5691/29945/10393/8697/5714/5690/7314/996/5704/6233/51434/5717/51433/9861 62 Newcastle_disease_virus R-HSA-69239 Synthesis of DNA 80/528 119/10654 7.16244975908054e-77 1.9584184055543073e-75 9.413505397648709e-76 5716/9491/5715/8454/23198/6500/5718/51343/23595/7311/5711/4172/5689/5701/4173/5688/143471/5706/25906/5687/5705/5684/10197/5720/5685/11065/5683/5698/5708/8318/5692/8881/5686/990/5713/29882/119504/5682/7316/10213/5709/246184/5694/5699/4174/5695/4175/5710/890/5700/81620/122706/7321/5707/5702/8900/51529/5693/5721/7324/5696/5719/64682/5691/29945/10393/8697/5714/5690/5111/4176/4171/7314/996/5704/6233/51434/5717/51433/9861 80 Newcastle_disease_virus R-HSA-69306 DNA Replication 82/528 127/10654 1.3868144958846635e-76 3.686615201560064e-75 1.7720407447415143e-75 5716/9491/5715/8454/23198/6500/5718/51343/23595/7311/5711/4172/5689/5701/4173/5688/143471/5706/25906/5687/5705/5684/10197/5720/5685/11065/5683/5698/5708/8318/5692/8881/5686/990/5713/29882/119504/5682/7316/10213/5709/246184/5694/5699/4174/5695/4175/5710/890/5700/81620/122706/7321/5707/5702/8900/51529/5693/8317/5721/7324/5696/5719/64682/5691/29945/10393/8697/5714/5690/5111/4176/4171/7314/996/5704/6233/51434/5717/51433/55388/9861 82 Newcastle_disease_virus R-HSA-5617833 Cilium Assembly 98/528 201/10654 3.321044505770687e-75 8.589836735196073e-74 4.128866142309503e-74 79959/115106/132320/347240/57545/84131/121441/26005/54930/7277/79441/22995/55559/5518/79867/10381/26123/10383/55835/54820/5116/5347/7846/7840/23322/7283/3320/22919/54806/9814/11258/9662/80184/55142/91147/5048/1781/22981/23354/80321/23332/8766/1453/8636/7531/22897/10142/54903/80776/22832/27077/22994/9793/11190/11064/4867/146057/4218/8655/79600/203068/10540/84902/5108/10733/9738/79598/261734/54801/8481/983/7532/1639/55125/1069/57787/140735/1454/93323/112752/10806/51259/55755/9657/4751/55722/10382/4957/117177/85302/5577/51134/10121/1778/95681/9702/5566/80254 98 Newcastle_disease_virus R-HSA-69206 G1/S Transition 81/528 131/10654 2.391970165614126e-73 6.02398802234926e-72 2.895542832059205e-72 5716/9491/5715/8454/6500/55957/5519/5718/23595/7311/5711/4172/5689/5928/5701/4173/5688/26271/5706/5518/5687/5705/91750/5684/10197/5720/5685/286826/5683/5698/5708/8318/5692/5686/990/5713/5682/7316/10213/5709/5694/5699/4174/891/993/5695/7465/4175/1163/5710/890/5700/81620/5707/5702/8900/983/5693/8317/5721/5696/7083/132660/5719/5691/5714/5690/5111/4176/4171/4609/7314/5704/6233/5515/5717/6241/7298/55388/9861/5516 81 Newcastle_disease_virus R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 54/528 55/10654 1.2499838511493018e-70 3.067268065512518e-69 1.4743399269966123e-69 5716/9491/5715/8454/23198/6500/5718/51343/7311/5711/5689/8945/5701/5688/143471/26271/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/991/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 54 Newcastle_disease_virus R-HSA-68949 Orc1 removal from chromatin 61/528 71/10654 2.4133556523028355e-70 5.773953398134534e-69 2.7753590001482604e-69 5716/9491/5715/8454/23198/6500/5718/23595/7311/5711/4172/5689/5701/4173/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/990/5713/5682/7316/10213/5709/5694/5699/4174/5695/4175/5710/890/5700/81620/122706/5707/5702/8900/5693/5721/5696/5719/5691/5714/5690/4176/4171/7314/5704/6233/5717/9861 61 Newcastle_disease_virus R-HSA-453279 Mitotic G1-G1/S phases 83/528 149/10654 8.021096978343836e-70 1.8722414166524513e-68 8.999279536678449e-69 5716/9491/5715/8454/6500/55957/7153/5519/5718/23595/7311/5711/4172/5689/5928/5701/4173/5688/26271/5706/5518/5687/5705/91750/5684/10197/5720/5685/4605/286826/5683/5698/5708/8318/5692/5686/990/5713/5682/7316/10213/5709/5694/5699/4174/891/993/5695/7465/4175/1163/5710/890/5700/81620/5707/5702/8900/983/5693/8317/5721/5696/7083/132660/5719/5691/5714/5690/5111/4176/4171/4609/7314/5704/6233/5515/5717/6241/7298/55388/9861/5516 83 Newcastle_disease_virus R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 51/528 52/10654 1.305540631809022e-66 2.839550874184623e-65 1.3648833878003409e-65 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/11200/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/993/5695/5710/5700/1111/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 51 Newcastle_disease_virus R-HSA-69610 p53-Independent DNA Damage Response 51/528 52/10654 1.305540631809022e-66 2.839550874184623e-65 1.3648833878003409e-65 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/11200/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/993/5695/5710/5700/1111/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 51 Newcastle_disease_virus R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 51/528 52/10654 1.305540631809022e-66 2.839550874184623e-65 1.3648833878003409e-65 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/11200/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/993/5695/5710/5700/1111/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 51 Newcastle_disease_virus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 61/528 77/10654 5.474558161548863e-66 1.1642560356893914e-64 5.596215009583281e-65 5716/9491/5715/23198/5718/7311/5711/5689/7277/5701/5688/143471/5706/9133/5687/10381/5705/10383/5684/5347/7846/10197/5720/5685/5683/5698/5708/3320/22919/5692/5686/5713/5682/7316/10213/5709/5694/5699/891/51512/5695/5710/5700/122706/5707/5702/7157/983/5693/5721/5696/5719/5691/5714/5690/10382/7314/5704/6233/5717/9861 61 Newcastle_disease_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 62/528 82/10654 9.192202261627763e-65 1.9123777313864716e-63 9.192202261627762e-64 5716/9491/5715/8454/23198/6500/5519/5718/7311/5711/5689/8945/5701/5688/143471/5706/5518/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/1487/5528/5682/7316/1499/10213/5709/5694/5699/5525/5695/5529/5710/5700/122706/5707/5702/5526/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5527/5515/5717/9861/5516 62 Newcastle_disease_virus R-HSA-68867 Assembly of the pre-replicative complex 57/528 68/10654 1.981225084277759e-64 4.0341115013910963e-63 1.9390713590803596e-63 5716/9491/5715/23198/5718/23595/7311/5711/4172/5689/5701/4173/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/990/5713/5682/7316/10213/5709/5694/5699/4174/5695/4175/5710/5700/81620/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/4176/4171/7314/5704/6233/5717/9861 57 Newcastle_disease_virus R-HSA-69481 G2/M Checkpoints 83/528 168/10654 4.560661476926018e-64 9.092818819621248e-63 4.3706339153874334e-63 5716/9491/5715/672/23198/63967/9656/5932/5718/7158/23595/9088/7311/5711/4172/5689/5701/4173/5688/11200/143471/5706/9133/472/5687/5705/5684/10197/5720/5685/7156/5683/5698/5708/8318/5692/5686/990/5713/11073/29086/995/5682/9156/7316/10213/5709/5694/5699/4174/891/7531/51512/993/5695/7465/4175/5710/5700/1111/122706/5707/5702/7157/983/7532/5693/8317/5721/5696/5719/641/5691/5714/5690/4176/4171/7314/5704/6233/5717/55388/9861 83 Newcastle_disease_virus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 51/528 54/10654 5.689957924398351e-64 1.111283619112086e-62 5.341593153516819e-63 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/6790/5691/5714/5690/7314/5704/6233/5717/9861 51 Newcastle_disease_virus R-HSA-180534 Vpu mediated degradation of CD4 50/528 52/10654 7.058436052184905e-64 1.3244947650864617e-62 6.366432517656973e-63 5716/9491/5715/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Newcastle_disease_virus R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/528 52/10654 7.058436052184905e-64 1.3244947650864617e-62 6.366432517656973e-63 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/472/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/7157/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Newcastle_disease_virus R-HSA-69541 Stabilization of p53 52/528 57/10654 3.949559978580984e-63 7.268709422119233e-62 3.4938415195139473e-62 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/11200/143471/5706/472/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/7157/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/4193/5717/9861 52 Newcastle_disease_virus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 53/528 60/10654 1.4954042015690536e-62 2.7001921149086498e-61 1.2978979862674804e-61 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/23291/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5970/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 53 Newcastle_disease_virus R-HSA-69615 G1/S DNA Damage Checkpoints 56/528 68/10654 2.018767383707403e-62 3.577704418903675e-61 1.7196907342692693e-61 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/11200/143471/5706/472/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/993/5695/5710/890/5700/1111/122706/5707/5702/7157/8900/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/4193/5717/9861 56 Newcastle_disease_virus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 52/528 59/10654 2.940579847393169e-61 5.116608934464113e-60 2.4593940541833777e-60 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/23291/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 52 Newcastle_disease_virus R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 48/528 50/10654 3.18903360722051e-61 5.449830646625051e-60 2.6195633202168475e-60 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Newcastle_disease_virus R-HSA-1169091 Activation of NF-kappaB in B cells 55/528 67/10654 3.7218873215455223e-61 6.248852924068536e-60 3.0036283647560356e-60 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/23291/10197/8517/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/3551/5695/5710/5700/122706/5707/5702/5970/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 55 Newcastle_disease_virus R-HSA-5610780 Degradation of GLI1 by the proteasome 52/528 60/10654 2.1082336124428726e-60 3.3626326118463816e-59 1.616312436206202e-59 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861/5566 52 Newcastle_disease_virus R-HSA-5610783 Degradation of GLI2 by the proteasome 52/528 60/10654 2.1082336124428726e-60 3.3626326118463816e-59 1.616312436206202e-59 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861/5566 52 Newcastle_disease_virus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 52/528 60/10654 2.1082336124428726e-60 3.3626326118463816e-59 1.616312436206202e-59 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861/5566 52 Newcastle_disease_virus R-HSA-69563 p53-Dependent G1 DNA Damage Response 54/528 66/10654 6.826151079984974e-60 1.053649448958971e-58 5.064563704504981e-59 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/11200/143471/5706/472/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/890/5700/122706/5707/5702/7157/8900/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/4193/5717/9861 54 Newcastle_disease_virus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 54/528 66/10654 6.826151079984974e-60 1.053649448958971e-58 5.064563704504981e-59 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/11200/143471/5706/472/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/890/5700/122706/5707/5702/7157/8900/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/4193/5717/9861 54 Newcastle_disease_virus R-HSA-69002 DNA Replication Pre-Initiation 60/528 85/10654 1.3239465055427875e-59 1.9797137590694494e-58 9.515865508588783e-59 5716/9491/5715/23198/5718/23595/7311/5711/4172/5689/5701/4173/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/8318/5692/5686/990/5713/5682/7316/10213/5709/5694/5699/4174/5695/4175/5710/5700/81620/122706/5707/5702/5693/8317/5721/5696/5719/5691/5714/5690/4176/4171/7314/5704/6233/5717/55388/9861 60 Newcastle_disease_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 60/528 85/10654 1.3239465055427875e-59 1.9797137590694494e-58 9.515865508588783e-59 5716/9491/5715/8454/6500/55957/5718/51343/7311/5711/5689/5928/5701/5688/5706/5687/5705/91750/5684/994/10197/5720/5685/286826/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/993/5695/7465/1163/5710/890/5700/5707/5702/8900/5693/5721/5696/132660/5719/5691/5714/5690/4609/7314/5704/6233/5717/9861 60 Newcastle_disease_virus R-HSA-9604323 Negative regulation of NOTCH4 signaling 49/528 54/10654 3.2531819166508565e-59 4.789684760361338e-58 2.3022518179375294e-58 5716/9491/5715/8454/6500/5718/7311/5711/5689/5701/5688/5706/5687/5705/5684/10197/10460/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/55294/10213/5709/5694/5699/5695/5710/5700/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Newcastle_disease_virus R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 51/528 59/10654 4.059005541769186e-59 5.885558035565319e-58 2.82900386244519e-58 5716/9491/5715/23198/5718/23595/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/990/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/81620/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 51 Newcastle_disease_virus R-HSA-1852241 Organelle biogenesis and maintenance 101/528 296/10654 4.70115002646297e-59 6.714926231828451e-58 3.227655242049203e-58 79959/115106/132320/347240/57545/84131/121441/26005/54930/7277/79441/22995/55559/5518/79867/10381/26123/10383/55835/54820/5116/5347/7846/7840/23322/7283/3320/22919/54806/9814/11258/9662/80184/55142/91147/5048/1781/22981/23354/80321/23332/2553/8766/1453/8636/7531/22897/10142/54903/80776/5469/22832/27077/22994/9793/11190/11064/4867/146057/4218/8655/79600/203068/10540/84902/5108/10733/9738/79598/261734/54801/8481/983/7532/1639/55125/1069/6256/57787/140735/1454/93323/112752/10806/51259/55755/9657/4751/55722/10382/4957/117177/85302/5577/51134/10121/1778/95681/9702/5566/80254 101 Newcastle_disease_virus R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 48/528 52/10654 6.436599523425462e-59 9.058567270467893e-58 4.354170265846636e-58 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Newcastle_disease_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 59/528 83/10654 6.556762999167154e-59 9.093945203192704e-58 4.3711753327781024e-58 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/4893/23291/10197/4773/8517/5720/5685/5683/5698/5708/5692/5686/5713/3845/5682/7316/10213/5709/5694/3265/5699/3551/5695/5710/5700/122706/5707/5702/5970/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 59 Newcastle_disease_virus R-HSA-195258 RHO GTPase Effectors 105/528 327/10654 1.813181849260554e-58 2.4788786139176428e-57 1.1915195009426497e-57 701/54821/9055/79172/7514/5519/9184/220134/9183/5905/55839/9928/147841/7277/348995/11130/23421/81565/2491/79682/79023/55920/1062/5518/699/10381/57122/79980/64105/10383/5903/54820/5347/57551/7846/10403/6232/5300/54908/332/84643/1780/22919/6249/6396/9475/1060/91687/55143/995/23122/5528/79003/5048/1781/1499/55055/23332/25936/5525/9735/7531/80776/5501/5529/5058/25909/1783/1058/4659/64946/9793/51143/57405/10726/8655/991/1856/401541/79019/998/5526/4085/81930/55746/7532/140735/83540/348235/80152/10382/5500/9212/11004/1063/23279/55166/5527/5515/1778/8379/3619/79902/5516/3796 105 Newcastle_disease_virus R-HSA-4641257 Degradation of AXIN 49/528 55/10654 2.8500357077919645e-58 3.8415270033195915e-57 1.8465020078652163e-57 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/8313/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Newcastle_disease_virus R-HSA-169911 Regulation of Apoptosis 48/528 53/10654 6.520226911791382e-58 8.666468270256045e-57 4.165700526977827e-57 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Newcastle_disease_virus R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 49/528 56/10654 2.1790606509299318e-57 2.856658962931431e-56 1.3731067115448883e-56 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/7415/5717/9861 49 Newcastle_disease_virus R-HSA-69202 Cyclin E associated events during G1/S transition 58/528 83/10654 3.329792738520061e-57 4.306231960491484e-56 2.0698711617827404e-56 5716/9491/5715/8454/6500/55957/5718/7311/5711/5689/5928/5701/5688/5706/5687/5705/91750/5684/10197/5720/5685/286826/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/993/5695/7465/1163/5710/890/5700/5707/5702/8900/5693/5721/5696/132660/5719/5691/5714/5690/4609/7314/5704/6233/5717/9861 58 Newcastle_disease_virus R-HSA-180585 Vif-mediated degradation of APOBEC3G 48/528 54/10654 5.607949667280063e-57 7.15574377544936e-56 3.4395424625984383e-56 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Newcastle_disease_virus R-HSA-4641258 Degradation of DVL 49/528 57/10654 1.483821758226751e-56 1.8684439771355273e-55 8.981026431372439e-56 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/1856/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Newcastle_disease_virus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 50/528 60/10654 2.7950913337683877e-56 3.473899229112139e-55 1.669794822770725e-55 5716/9491/5715/8454/6500/5718/7311/5711/5689/5701/5688/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/1163/5710/890/5700/5707/5702/8900/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Newcastle_disease_virus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 52/528 66/10654 4.866820131184836e-56 5.971213930184472e-55 2.870175974801313e-55 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/112399/5695/5710/5700/122706/7321/5707/5702/8453/5693/84962/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 52 Newcastle_disease_virus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 48/528 56/10654 2.8168269639742033e-55 3.412282790535839e-54 1.640177725858397e-54 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Newcastle_disease_virus R-HSA-5387390 Hh mutants abrogate ligand secretion 49/528 59/10654 5.1531155768396104e-55 6.164414508794385e-54 2.9630414566827754e-54 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/7415/5717/9861 49 Newcastle_disease_virus R-HSA-5687128 MAPK6/MAPK4 signaling 58/528 89/10654 2.0099947861320745e-54 2.374771617689377e-53 1.1414785205194497e-53 5716/9491/5715/23198/7514/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/2309/5682/7316/10213/5709/5694/5699/5695/5058/5710/5700/122706/5707/8555/5702/998/983/5693/5597/8556/5721/5696/5719/5691/5714/5690/4609/7314/5704/6233/5717/9861/5566 58 Newcastle_disease_virus R-HSA-2871837 FCERI mediated NF-kB activation 56/528 82/10654 2.454343056772638e-54 2.864397933330993e-53 1.376826592823675e-53 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/23291/10197/8517/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/3551/5695/5710/5700/122706/7321/5707/5702/5970/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 56 Newcastle_disease_virus R-HSA-8941858 Regulation of RUNX3 expression and activity 47/528 55/10654 5.321215431442885e-54 6.13542550348294e-53 2.949107347546659e-53 5716/9491/5715/5718/7311/5711/5689/5701/5688/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/2033/5682/7316/10213/5709/5694/5699/5695/5710/5700/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/4193/5717/9861 47 Newcastle_disease_virus R-HSA-5678895 Defective CFTR causes cystic fibrosis 49/528 61/10654 1.3050338240427521e-53 1.486806392391564e-52 7.146613798329357e-53 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/7415/5717/9861 49 Newcastle_disease_virus R-HSA-5658442 Regulation of RAS by GAPs 51/528 68/10654 5.4797998170597985e-53 6.169609911677915e-52 2.965538724526479e-52 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/4893/10197/5720/5685/5683/5698/5708/5692/5686/5713/3845/5682/7316/10213/5709/5694/3265/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 51 Newcastle_disease_virus R-HSA-1234174 Cellular response to hypoxia 53/528 75/10654 1.0175616528358051e-52 1.13233314158589e-51 5.442771631447329e-52 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/2033/5682/7316/10213/5709/5694/5699/112399/5695/5710/5700/122706/7321/5707/5702/8453/5693/84962/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 53 Newcastle_disease_virus R-HSA-8948751 Regulation of PTEN stability and activity 51/528 69/10654 2.0077889331517084e-52 2.2085678264668792e-51 1.061589550861823e-51 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5728/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/10273/5721/5696/4734/5719/5691/5714/5690/7314/5704/6233/5717/9861 51 Newcastle_disease_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 52/528 73/10654 4.973011502813692e-52 5.408150009309891e-51 2.5995287401071576e-51 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/55294/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/10273/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 52 Newcastle_disease_virus R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 44/528 50/10654 8.049462835070263e-52 8.655433632766564e-51 4.16039652149699e-51 5716/9491/5715/23198/5718/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/5704/5717/9861 44 Newcastle_disease_virus R-HSA-4608870 Asymmetric localization of PCP proteins 49/528 64/10654 1.043103339643766e-51 1.109166551154538e-50 5.3314170692903594e-51 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/1856/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Newcastle_disease_virus R-HSA-5358346 Hedgehog ligand biogenesis 49/528 65/10654 4.049826529328126e-51 4.2589933940296884e-50 2.04716505878125e-50 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/7415/5717/9861 49 Newcastle_disease_virus R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 44/528 51/10654 5.602917634114386e-51 5.828252365051596e-50 2.8014588170571935e-50 5716/9491/5715/23198/5718/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/5704/5717/9861 44 Newcastle_disease_virus R-HSA-5610787 Hedgehog 'off' state 61/528 113/10654 4.402780820544594e-50 4.530603489528147e-49 2.177719545645713e-49 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/7277/8945/5701/5688/143471/5706/5687/10381/5705/10383/5684/7846/10197/5720/5685/23322/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/54903/5710/5700/122706/5707/5702/8481/5693/5721/5696/5719/5691/5714/5690/10382/7314/5577/5704/6233/5717/9861/5566 61 Newcastle_disease_virus R-HSA-202424 Downstream TCR signaling 57/528 98/10654 2.34675083465124e-49 2.3891920731502514e-48 1.1484099829144367e-48 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/23291/10197/8517/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5728/5709/5694/5699/3551/5695/5710/5700/122706/7321/5707/5702/5970/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 57 Newcastle_disease_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 57/528 101/10654 2.5814598371262864e-48 2.6004811201366907e-47 1.2499700263979912e-47 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/23291/10197/4773/8517/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/3551/5695/5710/5700/122706/7321/5707/5702/5970/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 57 Newcastle_disease_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 59/528 112/10654 1.3048892418394413e-47 1.300811462958693e-46 6.25259428381399e-47 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/4893/23291/10197/4773/8517/5720/5685/5683/5698/5708/5692/5686/5713/3845/5682/7316/10213/5709/5694/3265/5699/3551/5695/5710/5700/122706/5707/5702/5970/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 59 Newcastle_disease_virus R-HSA-194315 Signaling by Rho GTPases 109/528 455/10654 1.2581796083666251e-46 1.2413174074297529e-45 5.9666249468932736e-46 701/1894/54821/9055/79172/7514/5519/9184/220134/9183/5905/55839/9928/147841/7277/348995/11130/23421/81565/2491/79682/79023/55920/1062/5518/699/10381/57122/79980/64105/10383/5903/54820/5347/57551/7846/10403/6232/5300/394/54908/332/84643/1780/22919/6249/6396/9475/1060/91687/55143/995/23122/5528/6453/79003/5048/1781/1499/55055/23332/25936/5525/9735/7531/80776/5501/5529/5058/25909/1783/1058/4659/64946/9793/51143/57405/10726/8655/991/1856/401541/79019/998/5526/4085/81930/55746/7532/140735/83540/348235/80152/10382/5500/9212/11004/1063/23279/55166/5527/29127/5515/1778/8379/3619/79902/5516/3796 109 Newcastle_disease_virus R-HSA-9013694 Signaling by NOTCH4 51/528 82/10654 2.4127833710048473e-46 2.3561568225016725e-45 1.1325309700634998e-45 5716/9491/5715/8454/6500/22938/5718/7311/5711/5689/5701/5688/5706/5687/5705/5684/10197/10460/5720/5685/5683/5698/5708/5692/5686/5713/2033/5682/7316/55294/10213/5709/5694/5699/5695/5710/5700/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 51 Newcastle_disease_virus R-HSA-9020702 Interleukin-1 signaling 56/528 103/10654 3.1073835420227843e-46 3.0038040906220246e-45 1.4438347771014956e-45 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/351/23291/10197/8517/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/3551/5695/5710/5700/122706/5707/5702/5970/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 56 Newcastle_disease_virus R-HSA-2262752 Cellular responses to stress 111/528 479/10654 5.570179059520984e-46 5.3306613599615814e-45 2.5622823673796522e-45 5716/9491/5715/23198/1912/5718/51343/7311/5711/5689/5928/7277/348995/538/5701/5688/143471/79023/5706/472/25906/5687/10381/57122/5705/10383/5684/5903/7846/10197/5720/5685/11065/5683/5698/5708/3320/1780/8726/5692/8881/5686/5713/29882/6396/2033/11258/119504/5682/1781/7316/10213/5709/246184/5694/5699/112399/7531/5695/1783/5710/890/5700/51143/122706/7321/5707/8655/5702/10540/7157/3297/8453/5970/8900/51529/55746/5693/84962/1639/9261/5721/7324/140735/5696/6045/5719/64682/5691/29945/10393/8697/5714/5690/10382/8480/23279/3308/7314/996/5704/10121/6233/7415/4193/51434/1778/5717/51433/9861/79902 111 Newcastle_disease_virus R-HSA-351202 Metabolism of polyamines 44/528 59/10654 1.3399086349549948e-45 1.2695965976751783e-44 6.102554179002947e-45 5716/9491/5715/23198/5718/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/5704/5717/9861 44 Newcastle_disease_virus R-HSA-162909 Host Interactions of HIV factors 61/528 129/10654 1.564893287375068e-45 1.4682381137430786e-44 7.057361884240503e-45 5716/9491/5715/23198/6500/7514/5718/7311/5711/5689/5905/348995/8945/5701/5688/143471/79023/5706/5687/57122/5705/5684/5903/10197/5720/5685/5683/5698/5708/5692/5686/5713/6396/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/55746/5693/5721/5696/5719/5691/5714/5690/8480/23279/7314/5704/6233/5717/9861/79902 61 Newcastle_disease_virus R-HSA-8953897 Cellular responses to external stimuli 112/528 493/10654 1.7061165934474888e-45 1.5851976504167445e-44 7.619549834814026e-45 5716/9491/5715/23198/1912/5718/51343/7311/5711/5689/5928/7277/348995/538/5701/5688/143471/79023/5706/472/25906/5687/10381/57122/5705/10383/5684/5903/7846/10197/5720/5685/11065/5683/5698/5708/3320/1780/8726/5692/8881/5686/5713/29882/6396/2033/11258/119504/5682/1781/7316/10213/5709/246184/5694/5699/112399/7531/5695/1783/5710/890/5700/51143/122706/7321/5707/8655/5702/10540/7157/3297/8453/5970/8900/51529/55746/5693/84962/1639/9261/5721/7324/140735/5696/6045/5719/64682/5691/29945/10393/8697/5714/5690/10382/8480/23279/3308/7314/996/5704/10121/6233/6620/7415/4193/51434/1778/5717/51433/9861/79902 112 Newcastle_disease_virus R-HSA-5619084 ABC transporter disorders 49/528 77/10654 2.8390592177190027e-45 2.612480453227967e-44 1.2557377309141741e-44 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/7415/5717/9861 49 Newcastle_disease_virus R-HSA-5621481 C-type lectin receptors (CLRs) 63/528 142/10654 7.237181688287415e-45 6.596174167324815e-44 3.170574834868772e-44 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/4893/23291/10197/4773/8517/5720/5685/5683/5698/5708/5692/5686/5713/3845/2033/5682/7316/10213/5709/5694/3265/5699/3551/5695/5058/5710/5700/122706/7321/5707/5702/5970/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861/5566 63 Newcastle_disease_virus R-HSA-1236974 ER-Phagosome pathway 50/528 83/10654 1.9552030483271293e-44 1.765216337027418e-43 8.484843417268674e-44 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/8517/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/3551/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Newcastle_disease_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 61/528 134/10654 2.783052315690163e-44 2.489141183285501e-43 1.1964523973995094e-43 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/4893/23291/10197/4773/8517/5720/5685/5683/5698/5708/5692/5686/5713/3845/5682/7316/10213/5709/5694/3265/5699/3551/5695/5058/5710/5700/122706/7321/5707/5702/5970/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 61 Newcastle_disease_virus R-HSA-202403 TCR signaling 58/528 119/10654 2.8721702196697106e-44 2.545061944651771e-43 1.2233317602296916e-43 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/23291/10197/8517/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5728/5709/5694/5699/3551/5695/5058/5710/5700/122706/7321/5707/5702/5970/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 58 Newcastle_disease_virus R-HSA-8878159 Transcriptional regulation by RUNX3 53/528 96/10654 2.9359243743814507e-44 2.5776877305349067e-43 1.2390139561609791e-43 5716/9491/5715/22938/5718/7311/5711/5689/5701/5688/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/3845/2033/2309/5682/7316/1499/10213/5709/5694/5699/5695/5710/5700/5707/5702/7157/5693/5721/5696/5719/5691/5714/5690/4609/7314/5704/6233/4193/5717/9861 53 Newcastle_disease_virus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 54/528 102/10654 9.206111497723035e-44 8.009317003019039e-43 3.84982844450236e-43 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/23291/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/8600/5714/5690/7314/5704/6233/4055/5717/9861 54 Newcastle_disease_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 50/528 88/10654 1.2165917171267206e-42 1.048899345306551e-41 5.041731440344968e-42 5716/9491/5715/23198/7514/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/9261/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Newcastle_disease_virus R-HSA-5358351 Signaling by Hedgehog 62/528 149/10654 4.324029664874174e-42 3.694728919004093e-41 1.7759407552161785e-41 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/7277/8945/5701/5688/143471/5706/5687/10381/5705/10383/5684/7846/10197/5720/5685/23322/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/54903/5710/5700/122706/5707/5702/8481/5693/5721/5696/5719/5691/5714/5690/10382/7314/5577/5704/6233/7415/5717/9861/5566 62 Newcastle_disease_virus R-HSA-5632684 Hedgehog 'on' state 48/528 85/10654 8.758406379220806e-41 7.417517614968417e-40 3.5653689685323635e-40 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Newcastle_disease_virus R-HSA-4086400 PCP/CE pathway 49/528 92/10654 6.213148983208981e-40 5.2157750674833295e-39 2.5070601160316943e-39 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/1856/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Newcastle_disease_virus R-HSA-8878166 Transcriptional regulation by RUNX2 55/528 121/10654 6.414143841503744e-40 5.337683179407898e-39 2.5656575366014972e-39 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/55294/10213/5709/5694/5699/891/5695/5710/5700/122706/5707/5702/23314/983/5693/10273/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 55 Newcastle_disease_virus R-HSA-446652 Interleukin-1 family signaling 58/528 140/10654 2.8882389016436975e-39 2.3624313067290755e-38 1.1355469185949579e-38 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/351/23291/10197/8517/5720/5685/5683/5698/5708/5692/5686/5713/5784/5682/7316/10213/5709/5694/5699/3551/5695/5710/5700/122706/5707/5702/5970/5693/5721/5696/5719/5691/5714/29110/5690/7314/5704/6233/5717/9861 58 Newcastle_disease_virus R-HSA-6807070 PTEN Regulation 58/528 140/10654 2.8882389016436975e-39 2.3624313067290755e-38 1.1355469185949579e-38 5716/9491/5715/23198/1912/5718/7311/5711/5689/5928/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/8726/5692/5686/5713/5682/7316/10213/5728/5709/5694/5699/5695/5710/5700/122706/5707/5702/3066/5978/7157/5693/10273/5721/5696/4734/6045/5719/5691/5714/5690/7314/5704/6233/5717/9861 58 Newcastle_disease_virus R-HSA-1236975 Antigen processing-Cross presentation 50/528 99/10654 3.196148172592194e-39 2.5921303399751947e-38 1.2459560672817027e-38 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/8517/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/3551/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Newcastle_disease_virus R-HSA-5689603 UCH proteinases 49/528 102/10654 4.30897875916974e-37 3.465287960105413e-36 1.6656556548051097e-36 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/9958/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Newcastle_disease_virus R-HSA-382556 ABC-family proteins mediated transport 49/528 103/10654 7.853763200180452e-37 6.26337615214391e-36 3.0106092267358396e-36 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/7415/5717/9861 49 Newcastle_disease_virus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 79/528 309/10654 1.1257273664230431e-35 8.903480079891341e-35 4.2796246987983453e-35 5716/9491/5715/8454/23198/6500/5718/51343/7311/5711/5689/8945/5701/5688/143471/5706/5687/26270/5705/5684/23291/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/26234/9903/5682/7316/55294/10213/5709/246184/5694/5699/5695/5710/5700/122706/7321/5707/5702/991/8453/84861/51529/5693/899/10273/5721/55958/7324/5696/4734/5719/64682/5691/29945/10393/8697/5714/5690/55658/7314/996/5704/6233/51434/5717/51433/9861 79 Newcastle_disease_virus R-HSA-109581 Apoptosis 61/528 178/10654 1.3722813508676935e-35 1.0764534858855597e-34 5.174175585238844e-35 5716/9491/5715/23198/63967/5718/1828/7311/5711/5689/7161/5701/5688/143471/5706/5687/5705/5684/10197/598/5720/5685/5683/5698/5708/5692/5686/5713/7159/9500/5682/7316/1499/10213/5709/5694/5699/7531/5695/5710/5700/122706/5707/8655/5702/7157/7532/5693/5721/8626/140735/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 61 Newcastle_disease_virus R-HSA-5357801 Programmed Cell Death 61/528 181/10654 4.152416491721377e-35 3.2307825874612664e-34 1.5529362489364497e-34 5716/9491/5715/23198/63967/5718/1828/7311/5711/5689/7161/5701/5688/143471/5706/5687/5705/5684/10197/598/5720/5685/5683/5698/5708/5692/5686/5713/7159/9500/5682/7316/1499/10213/5709/5694/5699/7531/5695/5710/5700/122706/5707/8655/5702/7157/7532/5693/5721/8626/140735/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 61 Newcastle_disease_virus R-HSA-1257604 PIP3 activates AKT signaling 72/528 264/10654 1.658976440716559e-34 1.280355204649796e-33 6.15426744136788e-34 5716/9491/7249/5715/23198/1912/5519/5718/7311/5711/5689/5928/5701/5688/143471/5706/5518/5687/5705/5684/1956/10197/5720/5685/5683/5698/5708/8726/5692/5686/5713/5528/2309/5682/7316/10213/5728/5709/5694/5699/5525/5695/5529/5710/5700/122706/5707/5702/3066/5978/5526/7157/5693/10273/5721/5696/4734/6045/5719/5691/5714/5690/7314/5704/6233/253260/5527/4193/5515/5717/9861/5516 72 Newcastle_disease_virus R-HSA-5689880 Ub-specific processing proteases 66/528 220/10654 1.9902019348528585e-34 1.5236986013233485e-33 7.32394312025852e-34 5716/9491/5715/23198/63967/5718/7311/5711/5689/10600/5701/5688/143471/5706/5687/5705/57695/5684/10197/8517/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5728/5709/1540/5694/5699/993/5695/5710/890/5700/122706/5707/5702/991/7157/9738/8900/9958/5693/8313/8237/5721/5696/10868/5719/5691/5714/5690/4609/7314/5704/6233/4193/5717/9861 66 Newcastle_disease_virus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 25/528 25/10654 1.3791238117460825e-33 1.0474773713023817e-32 5.0348964555809355e-33 701/7311/9184/25906/11065/8881/29882/119504/7316/246184/7321/991/4085/51529/7324/64682/29945/10393/8697/4751/7314/996/6233/51434/51433 25 Newcastle_disease_virus R-HSA-5619115 Disorders of transmembrane transporters 58/528 176/10654 8.544339316928035e-33 6.438529705748133e-32 3.094800067548737e-32 5716/9491/5715/23198/5718/7311/5711/5689/348995/5701/5688/143471/79023/5706/5687/57122/5705/5684/5903/10197/5720/5685/5683/5698/5708/5692/5686/5713/6396/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/55746/5693/5721/5696/5719/5691/5714/5690/8480/23279/7314/5704/6233/7415/5717/9861/79902 58 Newcastle_disease_virus R-HSA-201681 TCF dependent signaling in response to WNT 66/528 233/10654 9.724181454236693e-33 7.270345040394153e-32 3.494627710116312e-32 5716/9491/5715/23198/7514/5519/5718/7311/5711/5689/8945/5701/5688/143471/5706/5518/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/1487/2033/5528/5682/7316/1499/10213/5709/5694/5699/5525/5695/5529/5710/5700/122706/5707/5702/1856/5526/5693/8313/5721/1454/5696/5719/5691/5714/5690/4609/7314/5704/6233/5527/5515/5717/9861/5516 66 Newcastle_disease_virus R-HSA-9006925 Intracellular signaling by second messengers 75/528 305/10654 1.264243346362609e-32 9.378921569527261e-32 4.5081545684248066e-32 5716/9491/7249/5715/23198/1912/5519/5718/7311/5711/5689/5928/5701/5688/143471/5706/3838/5518/5687/5705/5684/1956/10197/5720/5685/5683/5698/5708/8726/5692/5686/5713/5528/2309/5682/7316/10213/5728/5709/5694/5699/5525/5695/5529/5710/5700/122706/5707/5702/3066/5978/5526/7157/5693/10273/5721/5696/4734/6045/5719/5691/5714/5690/7314/5577/5704/6233/253260/5527/4193/5515/5717/9861/5566/5516 75 Newcastle_disease_virus R-HSA-8951664 Neddylation 66/528 234/10654 1.2954175386239328e-32 9.536266034331566e-32 4.583785136669301e-32 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/26270/5705/5684/23291/10197/5720/5685/332/5683/5698/5708/5692/5686/5713/26234/9903/5682/7316/55294/10213/5709/5694/5699/80344/5695/10238/5710/5700/122706/7321/5707/10987/5702/8453/84861/5693/899/5721/55958/5696/5719/5691/5714/5690/7314/5704/6233/8451/5717/9861 66 Newcastle_disease_virus R-HSA-5688426 Deubiquitination 74/528 297/10654 1.342265787224816e-32 9.805712659344648e-32 4.713299710865766e-32 5716/9491/5715/672/23198/63967/5718/7311/5711/5689/10600/5701/5688/143471/5706/5687/5705/57695/5684/10197/7706/8517/5720/5685/5683/5698/5708/5692/5686/5713/2033/29086/5682/7316/10213/5728/5709/1540/5694/5699/993/5695/5710/890/5700/122706/7321/5707/5702/991/7157/9738/8900/983/9958/5693/8313/8237/5721/5696/10868/5719/5691/5714/5690/57506/4609/7314/5704/6233/7415/4193/5717/9861 74 Newcastle_disease_virus R-HSA-983169 Class I MHC mediated antigen processing & presentation 82/528 371/10654 4.3911113862436464e-32 3.1835557550266434e-31 1.53023578611521e-31 5716/9491/5715/8454/23198/6500/5718/51343/7311/5711/5689/8945/5701/5688/143471/5706/5687/26270/5705/5684/23291/10197/8517/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/26234/6396/9903/5682/7316/55294/10213/5709/246184/5694/5699/3551/5695/5710/5700/122706/7321/5707/5702/991/8453/84861/51529/5693/899/10273/5721/55958/7324/5696/4734/5719/64682/5691/29945/10393/8697/5714/5690/55658/7314/996/5704/6233/51434/5717/51433/9861 82 Newcastle_disease_virus R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs 49/528 130/10654 5.978410974229537e-31 4.3017588739380955e-30 2.067721088831268e-30 5716/9491/5715/23198/5718/7311/5711/5689/7161/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Newcastle_disease_virus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 23/528 23/10654 6.1233449445862515e-31 4.3731650089321216e-30 2.102043786947519e-30 7311/25906/11065/8881/29882/119504/7316/246184/891/7321/991/51529/983/7324/64682/29945/10393/8697/7314/996/6233/51434/51433 23 Newcastle_disease_virus R-HSA-5663202 Diseases of signal transduction 81/528 377/10654 9.099374077512876e-31 6.450445179392461e-30 3.1005274634488318e-30 5716/9491/7249/5715/8454/23198/6500/22938/5519/5718/7311/5711/5689/5701/5688/143471/5706/5518/5687/5705/23164/5684/4893/1956/10197/5720/5685/5683/5698/5708/3320/5692/5686/5713/3845/1487/2033/5528/2309/5682/7316/1499/55294/10213/5728/5709/5694/3265/5699/5525/5695/10142/5529/5710/9715/5700/11064/122706/5707/5702/3066/5526/5693/5721/5696/5719/5691/5714/5690/4609/7314/5704/6233/253260/5527/7415/4193/5515/5717/9861/5516 81 Newcastle_disease_virus R-HSA-5683057 MAPK family signaling cascades 71/528 294/10654 2.3780771080303386e-30 1.6733969061654664e-29 8.043496100690852e-30 5716/9491/5715/23198/7514/5519/5718/7311/5711/5689/5701/5688/143471/5706/5518/5687/5705/5684/4893/1956/10197/5720/5685/5683/5698/5708/5692/5686/5713/3845/5528/2309/5682/7316/10213/5709/5694/3265/5699/5525/5695/5529/5058/5710/5700/122706/5707/8555/5702/998/5526/983/5693/5597/8556/5721/5696/5719/5691/5714/5690/4609/7314/5704/6233/5527/5515/5717/9861/5566/5516 71 Newcastle_disease_virus R-HSA-3858494 Beta-catenin independent WNT signaling 51/528 146/10654 2.607493813665099e-30 1.8214391092536495e-29 8.755088717415661e-30 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/3845/5682/7316/1499/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/1856/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 51 Newcastle_disease_virus R-HSA-162906 HIV Infection 62/528 233/10654 4.359680927188788e-29 3.0233439473330946e-28 1.4532269757295962e-28 5716/9491/5715/23198/6500/7514/5718/7311/5711/5689/5905/348995/8945/5701/5688/143471/79023/5706/5687/57122/5705/5684/5903/10197/5720/5685/5683/7251/5698/5708/5692/5686/5713/6396/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/55746/5693/5721/5696/5719/5691/5714/5690/8480/23279/7314/5704/6233/5717/9861/79902 62 Newcastle_disease_virus R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 20/528 20/10654 5.648510942726257e-27 3.861160694420734e-26 1.855939309752913e-26 701/9184/25906/11065/8881/29882/119504/246184/7321/991/4085/51529/7324/64682/29945/10393/8697/996/51434/51433 20 Newcastle_disease_virus R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 20/528 20/10654 5.648510942726257e-27 3.861160694420734e-26 1.855939309752913e-26 701/9184/25906/11065/8881/29882/119504/246184/7321/991/4085/51529/7324/64682/29945/10393/8697/996/51434/51433 20 Newcastle_disease_virus R-HSA-5684996 MAPK1/MAPK3 signaling 62/528 255/10654 1.0165410224879306e-26 6.899501833481912e-26 3.316374966981901e-26 5716/9491/5715/23198/5519/5718/7311/5711/5689/5701/5688/143471/5706/5518/5687/5705/5684/4893/1956/10197/5720/5685/5683/5698/5708/5692/5686/5713/3845/5528/5682/7316/10213/5709/5694/3265/5699/5525/5695/5529/5710/5700/122706/5707/5702/5526/983/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5527/5515/5717/9861/5516 62 Newcastle_disease_virus R-HSA-5673001 RAF/MAP kinase cascade 61/528 249/10654 1.7295917417171748e-26 1.1656473921291101e-25 5.602902825280989e-26 5716/9491/5715/23198/5519/5718/7311/5711/5689/5701/5688/143471/5706/5518/5687/5705/5684/4893/1956/10197/5720/5685/5683/5698/5708/5692/5686/5713/3845/5528/5682/7316/10213/5709/5694/3265/5699/5525/5695/5529/5710/5700/122706/5707/5702/5526/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5527/5515/5717/9861/5516 61 Newcastle_disease_virus R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 19/528 19/10654 1.1801947716285595e-25 7.843377753114801e-25 3.7700666315912313e-25 51343/25906/11065/8881/29882/119504/246184/7321/991/51529/8556/7324/64682/29945/10393/8697/996/51434/51433 19 Newcastle_disease_virus R-HSA-176412 Phosphorylation of the APC/C 19/528 19/10654 1.1801947716285595e-25 7.843377753114801e-25 3.7700666315912313e-25 25906/5347/11065/8881/29882/119504/246184/891/7321/51529/983/7324/64682/29945/10393/8697/996/51434/51433 19 Newcastle_disease_virus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 50/528 171/10654 1.20779683811458e-25 7.971459131556228e-25 3.831631348501426e-25 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/6232/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/8453/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Newcastle_disease_virus R-HSA-195721 Signaling by WNT 69/528 331/10654 2.1539326104893116e-25 1.4118585672864872e-24 6.786363019349885e-25 5716/9491/5715/8454/23198/6500/7514/5519/5718/7311/5711/5689/8945/5701/5688/143471/5706/5518/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/3845/1487/2033/5528/5682/7316/1499/10213/5709/5694/5699/5525/5695/5529/5710/5700/122706/5707/5702/1856/5526/5693/8313/5721/1454/5696/5719/5691/5714/5690/4609/7314/5704/6233/5527/5515/5717/9861/5516 69 Newcastle_disease_virus R-HSA-9607240 FLT3 Signaling 61/528 267/10654 9.793166880719014e-25 6.375551499896665e-24 3.0645284116535693e-24 5716/9491/5715/23198/5519/5718/7311/5711/5689/5701/5688/143471/5706/5518/5687/5705/5684/4893/1956/10197/5720/5685/5683/5698/5708/5692/5686/5713/3845/5528/5682/7316/10213/5709/5694/3265/5699/5525/5695/5529/5710/5700/122706/5707/5702/5526/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5527/5515/5717/9861/5516 61 Newcastle_disease_virus R-HSA-376176 Signaling by ROBO receptors 55/528 218/10654 1.2694438647618569e-24 8.208498503899304e-24 3.94556876885442e-24 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/6232/5683/5698/5708/5692/5686/5713/23122/5682/7316/10213/5709/5694/5699/23332/5695/5058/5710/5700/122706/5707/5702/998/8453/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861/5566 55 Newcastle_disease_virus R-HSA-157118 Signaling by NOTCH 56/528 235/10654 1.000760684315061e-23 6.427704529459822e-23 3.089596743523007e-23 5716/9491/5715/8454/6500/22938/5718/7311/5711/5689/5701/5688/5706/5687/5705/5684/1956/10197/10460/5720/5685/5683/5698/5708/9787/5692/5686/5713/2033/5682/7316/55294/10213/5709/5694/5699/5695/5710/5700/5707/5702/3066/7157/5693/5721/5696/5719/5691/5714/5690/4609/7314/5704/6233/5717/9861 56 Newcastle_disease_virus R-HSA-8878171 Transcriptional regulation by RUNX1 54/528 239/10654 9.85438549076242e-22 6.287097943106423e-21 3.0220115505004754e-21 5716/9491/5715/23198/1912/5718/7311/5711/5689/7161/5701/5688/143471/5706/5687/5705/5684/10197/4773/5720/5685/5683/5698/5708/5692/5686/5713/2033/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/6045/5719/5691/5714/5690/51412/7314/5704/6233/5717/9861 54 Newcastle_disease_virus R-HSA-156711 Polo-like kinase mediated events 16/528 16/10654 1.064510925217992e-21 6.746602353865023e-21 3.2428809642402403e-21 55957/9088/5928/9133/91750/5347/4605/286826/2305/2033/995/891/993/7465/132660/1063 16 Newcastle_disease_virus R-HSA-5663205 Infectious disease 67/528 383/10654 3.2429539740261474e-20 2.041780890225673e-19 9.814202816131762e-20 5716/9491/5715/23198/6500/7514/5718/7311/5711/5689/5905/348995/8945/5701/5688/143471/79023/5706/3838/5687/57122/5705/5684/5903/10197/5720/5685/6232/5683/7251/402569/5698/5708/3320/5692/5686/5713/6396/5682/7316/1499/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/55746/5693/5721/5696/5719/5691/5714/5690/8480/23279/7314/5704/6233/5717/9861/79902 67 Newcastle_disease_virus R-HSA-449147 Signaling by Interleukins 74/528 461/10654 5.3165998160139446e-20 3.3254810613891143e-19 1.5984548466447153e-19 5716/9491/5715/8454/23198/6500/5519/5718/7311/5711/5689/8945/5701/5688/143471/5706/5518/5687/5705/5684/351/23291/10197/8517/598/5720/5685/332/5683/5698/5708/3320/5692/5686/5713/5528/5784/2309/5682/7316/10213/5709/5306/5694/5699/3551/5695/5710/5700/122706/5707/5702/998/7157/5970/5693/9261/5721/5696/5719/5691/5714/29110/5690/51231/4609/7314/5704/6233/5515/5717/9861/5566/5516 74 Newcastle_disease_virus R-HSA-8856688 Golgi-to-ER retrograde transport 37/528 133/10654 1.980784870143435e-18 1.2309163121605631e-17 5.916630131597273e-18 5861/81876/9183/3832/7277/10112/636/3833/1062/10381/10383/24137/7846/23299/146909/56992/84643/1780/9493/11258/5048/1781/1783/51143/8655/10540/81930/1639/140735/285643/10382/11004/10121/29127/1778/3835/3796 37 Newcastle_disease_virus R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 17/528 25/10654 3.822331421578471e-17 2.3599814002907074e-16 1.1343693251136106e-16 7514/5519/9088/9133/5518/5347/994/2305/995/891/993/7465/890/8900/983/5515/5516 17 Newcastle_disease_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 40/528 182/10654 6.521422952670294e-16 4.0006421575035075e-15 1.92298369117201e-15 672/1912/7153/9656/10274/7158/5905/348995/79023/57122/10735/10521/5903/8517/332/6396/1487/2033/55143/5885/10210/8243/9126/3066/23314/7157/5970/55746/1069/6256/6045/6790/641/5111/8480/9212/23279/4193/3619/79902 40 Newcastle_disease_virus R-HSA-68875 Mitotic Prophase 35/528 142/10654 1.0679153581394771e-15 6.5095222785954116e-15 3.1289239792621623e-15 8615/140609/5519/5861/81876/4926/348995/79023/9133/5518/57122/55844/5903/5347/23310/54892/6396/10051/891/84930/64689/26003/91754/55746/983/5862/8548/10592/2801/29781/8480/23279/5515/79902/5516 35 Newcastle_disease_virus R-HSA-2990846 SUMOylation 40/528 188/10654 2.121641747528277e-15 1.2850703496104818e-14 6.176931670019034e-15 672/1912/7153/9656/10274/7158/5905/348995/79023/57122/10735/10521/5903/8517/332/6396/1487/2033/55143/5885/10210/8243/9126/3066/23314/7157/5970/55746/1069/6256/6045/6790/641/5111/8480/9212/23279/4193/3619/79902 40 Newcastle_disease_virus R-HSA-5633007 Regulation of TP53 Activity 36/528 160/10654 8.95935672431708e-15 5.392518481239903e-14 2.5920151529470795e-14 672/5519/5932/7311/7161/5928/9891/11200/5518/472/5300/7156/11073/2033/7159/9156/7316/890/1111/3066/7157/8900/983/8626/6790/641/22974/9212/7314/6233/253260/5527/4193/5515/1263/5516 36 Newcastle_disease_virus R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 12/528 14/10654 1.6170876237977552e-14 9.672205349840323e-14 4.649126918418546e-14 8615/5861/81876/9133/5347/891/64689/26003/983/5862/8548/2801 12 Newcastle_disease_virus R-HSA-2132295 MHC class II antigen presentation 31/528 123/10654 2.486778264628108e-14 1.4781657138193163e-13 7.105080756080308e-14 3832/7277/10112/1062/10381/10383/24137/7846/56992/84643/1780/9493/6396/11258/1781/1783/51143/8655/10540/81930/1639/140735/285643/10382/11004/10121/29127/1778/3835/1785/3796 31 Newcastle_disease_virus R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic 39/528 202/10654 1.3806205770789954e-13 8.155888223855547e-13 3.9202806509650484e-13 5861/81876/9183/3832/7277/10112/636/3833/1062/10381/10383/24137/7846/23299/146909/56992/84643/1780/9493/11258/5048/1781/1783/8674/51143/8655/10540/81930/1639/140735/285643/7110/10382/11004/10121/29127/1778/3835/3796 39 Newcastle_disease_virus R-HSA-6804757 Regulation of TP53 Degradation 17/528 36/10654 1.823940613881869e-13 1.0708657469232813e-12 5.1473170698506725e-013 5519/7311/11200/5518/472/7316/890/7157/8900/983/7314/6233/253260/5527/4193/5515/5516 17 Newcastle_disease_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 17/528 37/10654 3.221384405316633e-13 1.8797956560292787e-12 9.035590405156409e-13 5519/7311/11200/5518/472/7316/890/7157/8900/983/7314/6233/253260/5527/4193/5515/5516 17 Newcastle_disease_virus R-HSA-69205 G1/S-Specific Transcription 15/528 28/10654 4.531976366429712e-13 2.6285462925292327e-12 1.2634600779137378e-12 55957/5928/26271/91750/286826/8318/990/81620/8900/983/7083/132660/5111/6241/7298 15 Newcastle_disease_virus R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 19/528 51/10654 1.2912098622666198e-12 7.443902639693706e-12 3.578051425558103e-12 7277/636/10381/10383/7846/23299/1780/11258/5048/1781/1783/51143/8655/10540/1639/140735/10382/10121/1778 19 Newcastle_disease_virus R-HSA-983189 Kinesins 20/528 59/10654 2.570117091479145e-12 1.4728156027218813e-11 7.079364443595249e-12 3832/7277/10112/3833/1062/10381/10383/24137/7846/146909/56992/84643/9493/81930/285643/10382/11004/29127/3835/3796 20 Newcastle_disease_virus R-HSA-1538133 G0 and Early G1 14/528 27/10654 5.034253875309144e-12 2.8677267611136017e-11 1.3784266563346466e-11 55957/7153/5928/91750/4605/286826/990/993/890/8900/983/132660/5111/4609 14 Newcastle_disease_virus R-HSA-4615885 SUMOylation of DNA replication proteins 17/528 45/10654 1.5418348328762782e-11 8.730981864275729e-11 4.196710195994603e-11 7153/5905/348995/79023/57122/5903/332/6396/55143/55746/6790/5111/8480/9212/23279/3619/79902 17 Newcastle_disease_virus R-HSA-68884 Mitotic Telophase/Cytokinesis 10/528 13/10654 2.057016743602471e-11 1.1579794256632735e-10 5.5660453062184506e-11 10274/23244/10112/10735/5347/23047/9493/5885/8243/9126 10 Newcastle_disease_virus R-HSA-5675221 Negative regulation of MAPK pathway 16/528 40/10654 2.2017364452269888e-11 1.2321998702235253e-10 5.922799794177864e-11 5519/7311/5518/4893/3845/5528/7316/3265/5525/5529/5526/7314/6233/5527/5515/5516 16 Newcastle_disease_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 23/528 92/10654 6.914970063361704e-11 3.847457180602994e-10 1.8493524588060368e-10 672/5932/7311/9891/11200/472/5300/7156/11073/9156/7316/890/1111/7157/8900/6790/641/22974/9212/7314/6233/4193/1263 23 Newcastle_disease_virus R-HSA-176187 Activation of ATR in response to replication stress 15/528 37/10654 7.480336275689489e-11 4.13796636753459e-10 1.9889911484492283e-10 63967/23595/4172/4173/8318/990/995/4174/993/4175/1111/8317/4176/4171/55388 15 Newcastle_disease_virus R-HSA-2468052 Establishment of Sister Chromatid Cohesion 9/528 11/10654 8.49538448266537e-11 4.672461465465953e-10 2.245906242543718e-10 10274/23244/10735/113130/157570/23047/5885/8243/9126 9 Newcastle_disease_virus R-HSA-3700989 Transcriptional Regulation by TP53 49/528 365/10654 1.348726200836389e-10 7.375605566859568e-10 3.545223156484223e-10 7249/672/9656/5519/5932/7311/7161/5928/9891/11200/5518/472/55835/5300/7156/332/28984/11073/2033/995/7159/9156/7316/5728/891/7531/890/1111/3066/9540/7157/8900/7248/983/7532/8626/6790/641/22974/5111/9212/7314/6233/253260/5527/4193/5515/1263/5516 49 Newcastle_disease_virus R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 10/528 15/10654 1.9731765339090398e-10 1.0432762115751111e-9 5.014702793359991e-10 5519/5518/5528/1499/5525/5529/5526/5527/5515/5516 10 Newcastle_disease_virus R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 10/528 15/10654 1.9731765339090398e-10 1.0432762115751111e-9 5.014702793359991e-10 5519/5518/5528/1499/5525/5529/5526/5527/5515/5516 10 Newcastle_disease_virus R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 10/528 15/10654 1.9731765339090398e-10 1.0432762115751111e-9 5.014702793359991e-10 5519/5518/5528/1499/5525/5529/5526/5527/5515/5516 10 Newcastle_disease_virus R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 10/528 15/10654 1.9731765339090398e-10 1.0432762115751111e-9 5.014702793359991e-10 5519/5518/5528/1499/5525/5529/5526/5527/5515/5516 10 Newcastle_disease_virus R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 10/528 15/10654 1.9731765339090398e-10 1.0432762115751111e-9 5.014702793359991e-10 5519/5518/5528/1499/5525/5529/5526/5527/5515/5516 10 Newcastle_disease_virus R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 10/528 15/10654 1.9731765339090398e-10 1.0432762115751111e-9 5.014702793359991e-10 5519/5518/5528/1499/5525/5529/5526/5527/5515/5516 10 Newcastle_disease_virus R-HSA-5685942 HDR through Homologous Recombination (HRR) 19/528 67/10654 3.0602283343311427e-10 1.6091420417334636e-9 7.734643042814976e-10 146956/672/5932/7311/84464/472/80198/7156/5888/11073/9156/7316/1111/641/79008/5111/7314/6233/675 19 Newcastle_disease_virus R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic 23/528 99/10654 3.3988171794448206e-10 1.7774142299063896e-9 8.543474877292991e-10 5861/81876/9183/3832/7277/10112/3833/1062/10381/10383/24137/7846/146909/56992/84643/9493/81930/285643/10382/11004/29127/3835/3796 23 Newcastle_disease_virus R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 14/528 35/10654 4.028915080185038e-10 2.095473767248414e-9 1.0072287700462596e-9 140609/348995/79023/9133/57122/5903/6396/891/91754/55746/983/8480/23279/79902 14 Newcastle_disease_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 10/528 16/10654 5.029368102952093e-10 2.6016785267703526e-9 1.2505455823556554e-9 8454/6500/7311/8945/23291/8517/7316/3551/7314/6233 10 Newcastle_disease_virus R-HSA-5693532 DNA Double-Strand Break Repair 30/528 166/10654 5.31788667888148e-10 2.73613846865031e-9 1.3151762754223014e-9 146956/672/63967/9656/5932/7158/7311/84464/11200/3838/472/80198/7156/5888/11073/2072/5591/29086/9156/7316/890/1111/7157/8900/641/79008/5111/7314/6233/675 30 Newcastle_disease_virus R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 24/528 110/10654 5.588890323132314e-10 2.860196812426537e-9 1.3748072452624941e-9 51343/7311/25906/11065/8881/29882/119504/7316/246184/890/7321/5970/8900/51529/7324/64682/29945/10393/8697/7314/996/6233/51434/51433 24 Newcastle_disease_virus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 20/528 77/10654 5.86446247026964e-10 2.985260948961726e-9 1.4349216682574649e-9 672/1912/9656/10274/348995/79023/57122/10735/5903/6396/5885/8243/9126/55746/1069/6045/641/8480/23279/79902 20 Newcastle_disease_virus R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 17/528 55/10654 6.002695221279021e-10 3.039459961250806e-9 1.4609734400996558e-9 7277/10381/10383/7846/3320/1780/11258/1781/1783/51143/8655/10540/1639/140735/10382/10121/1778 17 Newcastle_disease_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 22/528 94/10654 7.107116110863373e-10 3.579742167419078e-9 1.7206702163142904e-9 8454/6500/5519/7311/8945/5518/351/23291/8517/5528/7316/3551/7321/5970/9261/29110/51231/7314/6233/10010/5515/5516 22 Newcastle_disease_virus R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 26/528 132/10654 1.130970923393546e-9 5.66669724443782e-9 2.723804318120582e-9 146956/672/63967/9656/5932/7158/7311/84464/472/80198/7156/5888/11073/2072/29086/9156/7316/890/1111/8900/641/79008/5111/7314/6233/675 26 Newcastle_disease_virus R-HSA-196299 Beta-catenin phosphorylation cascade 10/528 17/10654 1.167479741108527e-9 5.819156834587814e-9 2.797086879739179e-9 5519/5518/5528/1499/5525/5529/5526/5527/5515/5516 10 Newcastle_disease_virus R-HSA-1169408 ISG15 antiviral mechanism 19/528 72/10654 1.1829558728978557e-9 5.865744924161906e-9 2.8194803188239043e-9 7311/348995/79023/3838/57122/5903/7706/5300/402569/6396/7316/55746/7324/4734/8480/23279/7314/6233/79902 19 Newcastle_disease_virus R-HSA-2465910 MASTL Facilitates Mitotic Progression 8/528 10/10654 1.424419263826481e-9 7.026645543721353e-9 3.3774889760834083e-9 5519/5518/55844/891/84930/983/5515/5516 8 Newcastle_disease_virus R-HSA-2559583 Cellular Senescence 32/528 195/10654 1.770884927475858e-9 8.690958336381519e-9 4.177472136609716e-9 1912/51343/7311/5928/472/25906/11065/8726/8881/29882/119504/7316/246184/890/7321/7157/5970/8900/51529/9261/7324/6045/64682/29945/10393/8697/7314/996/6233/4193/51434/51433 32 Newcastle_disease_virus R-HSA-166166 MyD88-independent TLR4 cascade 22/528 99/10654 2.03867177792679e-9 9.903598433888011e-9 4.760350344397581e-9 8454/6500/5519/7311/8945/5518/351/23291/8517/5528/7316/3551/7321/5970/9261/29110/51231/7314/6233/10010/5515/5516 22 Newcastle_disease_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 22/528 99/10654 2.03867177792679e-9 9.903598433888011e-9 4.760350344397581e-9 8454/6500/5519/7311/8945/5518/351/23291/8517/5528/7316/3551/7321/5970/9261/29110/51231/7314/6233/10010/5515/5516 22 Newcastle_disease_virus R-HSA-71291 Metabolism of amino acids and derivatives 47/528 372/10654 2.5176363097292546e-9 1.216857549702473e-8 5.8490540529063485e-9 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/6232/5683/5698/5708/5692/5686/5713/5682/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/5704/6233/5717/9861 47 Newcastle_disease_virus R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 9/528 14/10654 2.703276967691386e-9 1.2681549304316944e-8 6.09562453499038e-9 5519/5518/5528/5525/5529/5526/5527/5515/5516 9 Newcastle_disease_virus R-HSA-4839744 truncated APC mutants destabilize the destruction complex 9/528 14/10654 2.703276967691386e-9 1.2681549304316944e-8 6.09562453499038e-9 5519/5518/5528/5525/5529/5526/5527/5515/5516 9 Newcastle_disease_virus R-HSA-4839748 AMER1 mutants destabilize the destruction complex 9/528 14/10654 2.703276967691386e-9 1.2681549304316944e-8 6.09562453499038e-9 5519/5518/5528/5525/5529/5526/5527/5515/5516 9 Newcastle_disease_virus R-HSA-5467337 APC truncation mutants have impaired AXIN binding 9/528 14/10654 2.703276967691386e-9 1.2681549304316944e-8 6.09562453499038e-9 5519/5518/5528/5525/5529/5526/5527/5515/5516 9 Newcastle_disease_virus R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 9/528 14/10654 2.703276967691386e-9 1.2681549304316944e-8 6.09562453499038e-9 5519/5518/5528/5525/5529/5526/5527/5515/5516 9 Newcastle_disease_virus R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 9/528 14/10654 2.703276967691386e-9 1.2681549304316944e-8 6.09562453499038e-9 5519/5518/5528/5525/5529/5526/5527/5515/5516 9 Newcastle_disease_virus R-HSA-5693538 Homology Directed Repair 26/528 138/10654 3.0709309916661104e-9 1.4336004678168134e-8 6.8908695422751746e-9 146956/672/63967/9656/5932/7158/7311/84464/472/80198/7156/5888/11073/2072/29086/9156/7316/890/1111/8900/641/79008/5111/7314/6233/675 26 Newcastle_disease_virus R-HSA-2514853 Condensation of Prometaphase Chromosomes 8/528 11/10654 4.99632704782601e-9 2.3211092159075204e-8 1.1156846805825071e-8 9133/10051/64151/23397/891/9918/983/10592 8 Newcastle_disease_virus R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 10/528 19/10654 5.066781543119874e-9 2.342468568485855e-8 1.1259514540266387e-8 55957/7153/5928/91750/286826/990/993/132660/5111/4609 10 Newcastle_disease_virus R-HSA-450294 MAP kinase activation 17/528 64/10654 7.998855259408083e-9 3.678299695181713e-8 1.7680437406307084e-8 8454/6500/5519/7311/8945/5518/23291/8517/5528/7316/3551/9261/51231/7314/6233/5515/5516 17 Newcastle_disease_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 19/528 80/10654 8.033068299822131e-9 3.678299695181713e-8 1.7680437406307084e-8 7311/348995/79023/3838/57122/5903/7706/5300/402569/6396/7316/55746/7324/4734/8480/23279/7314/6233/79902 19 Newcastle_disease_virus R-HSA-6807878 COPI-mediated anterograde transport 21/528 101/10654 1.679855837522967e-8 7.655343030997521e-8 3.6796842155264995e-8 8615/5861/81876/7277/10381/10383/7846/1780/11258/1781/64689/1783/51143/8655/10540/1639/140735/2801/10382/10121/1778 21 Newcastle_disease_virus R-HSA-5673000 RAF activation 12/528 32/10654 1.7629028231226893e-8 7.995725126674947e-8 3.8432952542011237e-8 5519/5518/4893/3845/5528/3265/5525/5529/5526/5527/5515/5516 12 Newcastle_disease_virus R-HSA-2980766 Nuclear Envelope Breakdown 15/528 52/10654 1.792752731870018e-8 8.092756435847205e-8 3.8899351729255106e-8 140609/348995/79023/9133/57122/5903/5347/6396/891/91754/55746/983/8480/23279/79902 15 Newcastle_disease_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 19/528 85/10654 2.3380765760896526e-8 1.0407159457292082e-7 5.002396395354605e-8 8454/6500/5519/7311/8945/5518/351/23291/8517/5528/7316/3551/5970/9261/51231/7314/6233/5515/5516 19 Newcastle_disease_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 19/528 85/10654 2.3380765760896526e-8 1.0407159457292082e-7 5.002396395354605e-8 8454/6500/5519/7311/8945/5518/351/23291/8517/5528/7316/3551/5970/9261/51231/7314/6233/5515/5516 19 Newcastle_disease_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 19/528 85/10654 2.3380765760896526e-8 1.0407159457292082e-7 5.002396395354605e-8 8454/6500/5519/7311/8945/5518/351/23291/8517/5528/7316/3551/5970/9261/51231/7314/6233/5515/5516 19 Newcastle_disease_virus R-HSA-5693568 Resolution of D-loop Structures through Holliday Junction Intermediates 12/528 33/10654 2.6468040018451933e-8 1.1672771565741244e-7 5.6107365937732204e-8 146956/672/5932/84464/472/80198/7156/5888/9156/641/79008/675 12 Newcastle_disease_virus R-HSA-68962 Activation of the pre-replicative complex 12/528 33/10654 2.6468040018451933e-8 1.1672771565741244e-7 5.6107365937732204e-8 23595/4172/4173/8318/990/4174/4175/81620/8317/4176/4171/55388 12 Newcastle_disease_virus R-HSA-432142 Platelet sensitization by LDL 9/528 17/10654 2.8700396067529572e-8 1.259921056725954e-7 6.056046876634681e-8 5519/5518/5528/5525/5529/5526/5527/5515/5516 9 Newcastle_disease_virus R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 8/528 13/10654 3.5666280255797915e-8 1.5585675892602103e-7 7.491547450989515e-8 11200/995/891/7531/7465/1111/983/7532 8 Newcastle_disease_virus R-HSA-5693537 Resolution of D-Loop Structures 12/528 34/10654 3.9082419188479465e-8 1.7000852346988567e-7 8.171778557591162e-8 146956/672/5932/84464/472/80198/7156/5888/9156/641/79008/675 12 Newcastle_disease_virus R-HSA-448424 Interleukin-17 signaling 17/528 72/10654 5.4315286208848836e-8 2.3520239322112368e-7 1.1305444188267179e-7 8454/6500/5519/7311/8945/5518/23291/8517/5528/7316/3551/9261/51231/7314/6233/5515/5516 17 Newcastle_disease_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 23/528 129/10654 7.374379349953514e-8 3.178955422479961e-7 1.5280245499903677e-7 8454/6500/5519/7311/8945/5518/351/23291/8517/5528/7316/3551/7321/5970/9261/29110/51231/7314/6233/10010/5515/1785/5516 23 Newcastle_disease_virus R-HSA-2470946 Cohesin Loading onto Chromatin 7/528 10/10654 7.439828961486514e-8 3.1927875857141677e-7 1.534673238692285e-7 10274/23244/10735/23047/5885/8243/9126 7 Newcastle_disease_virus R-HSA-606279 Deposition of new CENPA-containing nucleosomes at the centromere 17/528 74/10654 8.38044383424598e-8 3.5644821108326235e-7 1.713335183890289e-7 79172/5928/55839/23421/2491/79682/55355/64105/55320/1060/91687/1058/64946/401541/79019/80152/55166 17 Newcastle_disease_virus R-HSA-774815 Nucleosome assembly 17/528 74/10654 8.38044383424598e-8 3.5644821108326235e-7 1.713335183890289e-7 79172/5928/55839/23421/2491/79682/55355/64105/55320/1060/91687/1058/64946/401541/79019/80152/55166 17 Newcastle_disease_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 19/528 92/10654 9.086990424619099e-8 3.847898157681627e-7 1.849564422710082e-7 8454/6500/5519/7311/8945/5518/351/23291/8517/5528/7316/3551/5970/9261/51231/7314/6233/5515/5516 19 Newcastle_disease_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 9/528 19/10654 9.973075913690206e-8 4.1677876198259947e-7 2.0033252927063297e-7 7311/4893/1956/3320/3845/7316/3265/7314/6233 9 Newcastle_disease_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 9/528 19/10654 9.973075913690206e-8 4.1677876198259947e-7 2.0033252927063297e-7 7311/4893/1956/3320/3845/7316/3265/7314/6233 9 Newcastle_disease_virus R-HSA-6804760 Regulation of TP53 Activity through Methylation 9/528 19/10654 9.973075913690206e-8 4.1677876198259947e-7 2.0033252927063297e-7 7311/11200/472/2033/7316/7157/7314/6233/4193 9 Newcastle_disease_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 19/528 93/10654 1.0902875093503396e-7 4.5169053958799787e-7 2.1711353000050053e-7 8454/6500/5519/7311/8945/5518/351/23291/8517/5528/7316/3551/5970/9261/51231/7314/6233/5515/5516 19 Newcastle_disease_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 19/528 93/10654 1.0902875093503396e-7 4.5169053958799787e-7 2.1711353000050053e-7 8454/6500/5519/7311/8945/5518/351/23291/8517/5528/7316/3551/5970/9261/51231/7314/6233/5515/5516 19 Newcastle_disease_virus R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 11/528 31/10654 1.3680502238511797e-7 5.643207173386116e-7 2.712513374877339e-7 5519/5518/5528/1499/5525/5529/1856/5526/5527/5515/5516 11 Newcastle_disease_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 19/528 95/10654 1.5569047406937185e-7 6.340246114229314e-7 3.047558215826002e-7 8454/6500/5519/7311/8945/5518/351/23291/8517/5528/7316/3551/5970/9261/51231/7314/6233/5515/5516 19 Newcastle_disease_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 19/528 95/10654 1.5569047406937185e-7 6.340246114229314e-7 3.047558215826002e-7 8454/6500/5519/7311/8945/5518/351/23291/8517/5528/7316/3551/5970/9261/51231/7314/6233/5515/5516 19 Newcastle_disease_virus R-HSA-69473 G2/M DNA damage checkpoint 19/528 95/10654 1.5569047406937185e-7 6.340246114229314e-7 3.047558215826002e-7 672/9656/5932/7158/11200/472/7156/11073/29086/995/9156/891/7531/7465/1111/7157/983/7532/641 19 Newcastle_disease_virus R-HSA-5689896 Ovarian tumor domain proteases 12/528 38/10654 1.6082217015359179e-7 6.521475289702854e-7 3.134669418247975e-7 7311/7706/8517/7316/5728/7321/7157/983/57506/7314/6233/7415 12 Newcastle_disease_virus R-HSA-983231 Factors involved in megakaryocyte development and platelet production 26/528 168/10654 2.0300722068859235e-7 8.197380177172274e-7 3.9402245365718346e-7 3832/7277/10112/3833/1062/10381/10383/24137/7846/146909/56992/84643/9493/7465/3066/998/7157/81930/285643/10382/11004/5577/29127/3835/5566/3796 26 Newcastle_disease_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 10/528 26/10654 2.1250490276433572e-7 8.544839997708793e-7 4.1072376164535477e-7 7514/7311/9110/7316/5501/9958/10273/5500/7314/6233 10 Newcastle_disease_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 19/528 97/10654 2.2002435974515486e-7 8.810180429962895e-7 4.2347784720824787e-7 8454/6500/5519/7311/8945/5518/351/23291/8517/5528/7316/3551/5970/9261/51231/7314/6233/5515/5516 19 Newcastle_disease_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 19/528 98/10654 2.6058405836348246e-7 1.0347674018832064e-6 4.973803603618336e-7 8454/6500/5519/7311/8945/5518/351/23291/8517/5528/7316/3551/5970/9261/51231/7314/6233/5515/5516 19 Newcastle_disease_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 19/528 98/10654 2.6058405836348246e-7 1.0347674018832064e-6 4.973803603618336e-7 8454/6500/5519/7311/8945/5518/351/23291/8517/5528/7316/3551/5970/9261/51231/7314/6233/5515/5516 19 Newcastle_disease_virus R-HSA-389513 CTLA4 inhibitory signaling 9/528 21/10654 2.901982428688454e-7 1.1476021422540705e-6 5.516164947093754e-7 5519/5518/5528/5525/5529/5526/5527/5515/5516 9 Newcastle_disease_virus R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 8/528 16/10654 3.1232058006261577e-7 1.2300032720984499e-6 5.912241433284085e-7 55957/5928/91750/4605/286826/890/983/132660 8 Newcastle_disease_virus R-HSA-165054 Rev-mediated nuclear export of HIV RNA 11/528 34/10654 4.0351714818979126e-7 1.5761873910923685e-6 7.576240333359346e-7 7514/5905/348995/79023/57122/5903/6396/55746/8480/23279/79902 11 Newcastle_disease_virus R-HSA-4791275 Signaling by WNT in cancer 11/528 34/10654 4.0351714818979126e-7 1.5761873910923685e-6 7.576240333359346e-7 5519/5518/1487/5528/1499/5525/5529/5526/5527/5515/5516 11 Newcastle_disease_virus R-HSA-176974 Unwinding of DNA 7/528 12/10654 4.499693282271438e-7 1.7504904354202301e-6 8.414060609125453e-7 4172/4173/8318/4174/4175/4176/4171 7 Newcastle_disease_virus R-HSA-73894 DNA Repair 39/528 334/10654 4.939659624943368e-7 1.9138681218910133e-6 9.199366103133399e-7 146956/672/63967/9656/5932/7158/7311/84464/9557/11200/3838/472/7706/80198/7156/5888/11073/2072/5591/2033/29086/9156/7316/328/890/1111/10987/7157/8900/1069/641/79008/57697/5111/7314/6233/7415/8451/675 39 Newcastle_disease_virus R-HSA-199977 ER to Golgi Anterograde Transport 24/528 154/10654 5.250871291433621e-7 2.0262434781862805e-6 9.739519330884941e-7 8615/5861/81876/7277/10381/10383/7846/1780/6396/11258/1781/1453/64689/1783/51143/8655/10540/1639/140735/23243/2801/10382/10121/1778 24 Newcastle_disease_virus R-HSA-177243 Interactions of Rev with host cellular proteins 11/528 36/10654 7.740490683089637e-7 2.9749596721754143e-6 1.4299701663539088e-6 7514/5905/348995/79023/57122/5903/6396/55746/8480/23279/79902 11 Newcastle_disease_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 16/528 78/10654 1.042646366984096e-6 3.991250292815119e-6 1.9184693152507363e-6 7311/351/7706/8517/5300/2033/7316/1540/3551/7321/5970/29110/57506/7314/6233/10010 16 Newcastle_disease_virus R-HSA-5693607 Processing of DNA double-strand break ends 18/528 98/10654 1.2393909852702837e-6 4.7254867446361015e-6 2.2713938375471333e-6 672/63967/9656/5932/7158/7311/472/7156/11073/29086/9156/7316/890/1111/8900/641/7314/6233 18 Newcastle_disease_virus R-HSA-400253 Circadian Clock 15/528 70/10654 1.2611662337109157e-6 4.789428911354549e-6 2.3021288393135763e-6 8454/6500/7311/8945/6720/2033/7316/1453/5469/5501/6256/1454/5500/7314/6233 15 Newcastle_disease_virus R-HSA-3371556 Cellular response to heat stress 17/528 89/10654 1.384679243449504e-6 5.237699746961167e-6 2.5175986244536432e-6 348995/79023/472/57122/5903/3320/6396/2033/7531/3297/55746/9261/8480/23279/3308/7415/79902 17 Newcastle_disease_virus R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 10/528 31/10654 1.4170102480575437e-6 5.338892942484525e-6 2.5662390319152364e-6 7514/348995/79023/57122/5903/6396/55746/8480/23279/79902 10 Newcastle_disease_virus R-HSA-70171 Glycolysis 15/528 71/10654 1.5272042445120686e-6 5.7315076941099985e-6 2.754956676374712e-6 5519/348995/79023/5518/57122/5903/6396/5528/55746/8480/23279/5515/79902/5566/5516 15 Newcastle_disease_virus R-HSA-1643713 Signaling by EGFR in Cancer 9/528 25/10654 1.6873096093474397e-6 6.307637875568359e-6 3.0318844542961806e-6 7311/4893/1956/3320/3845/7316/3265/7314/6233 9 Newcastle_disease_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 10/528 32/10654 1.9705464775689846e-6 7.337793692737425e-6 3.527048169967832e-6 7514/7311/9110/7316/5501/9958/10273/5500/7314/6233 10 Newcastle_disease_virus R-HSA-168898 Toll-like Receptor Cascades 23/528 155/10654 2.1723645740014e-6 8.057956966354029e-6 3.8732081551962945e-6 8454/6500/5519/7311/8945/5518/351/23291/8517/5528/7316/3551/7321/5970/9261/29110/51231/7314/6233/10010/5515/1785/5516 23 Newcastle_disease_virus R-HSA-168276 NS1 Mediated Effects on Host Pathways 11/528 40/10654 2.48560262054628e-6 9.18425369831193e-6 4.41458380483123e-6 348995/79023/3838/57122/5903/402569/6396/55746/8480/23279/79902 11 Newcastle_disease_virus R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 10/528 33/10654 2.703126774473153e-6 9.94958585834926e-6 4.782455062529425e-6 7514/348995/79023/57122/5903/6396/55746/8480/23279/79902 10 Newcastle_disease_virus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 12/528 49/10654 3.3234537589577954e-6 1.2185997116178583e-5 5.857428080921785e-6 55835/28984/2033/995/891/890/7157/8900/983/6790/5111/1263 12 Newcastle_disease_virus R-HSA-4085377 SUMOylation of SUMOylation proteins 10/528 34/10654 3.6612974520912314e-6 1.3322667915023987e-5 6.403790220387705e-6 348995/79023/57122/5903/6396/10210/55746/8480/23279/79902 10 Newcastle_disease_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 10/528 34/10654 3.6612974520912314e-6 1.3322667915023987e-5 6.403790220387705e-6 7311/7706/5300/7316/1540/7321/29110/57506/7314/6233 10 Newcastle_disease_virus R-HSA-168253 Host Interactions with Influenza Factors 11/528 42/10654 4.2047671720025825e-6 1.5242280998509362e-5 7.326488254246923e-6 348995/79023/3838/57122/5903/402569/6396/55746/8480/23279/79902 11 Newcastle_disease_virus R-HSA-1295596 Spry regulation of FGF signaling 7/528 16/10654 5.459945263090515e-6 1.9717613648217446e-5 9.477640834043914e-6 7311/5518/7316/7314/6233/5515/5516 7 Newcastle_disease_virus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 14/528 69/10654 5.643650757165199e-6 2.0304412686492842e-5 9.75969679810523e-6 348995/79023/472/57122/5903/6396/7531/3297/55746/9261/8480/23279/3308/79902 14 Newcastle_disease_virus R-HSA-69231 Cyclin D associated events in G1 11/528 44/10654 6.883104264467439e-6 2.4556739122413945e-5 1.1803657258422587e-5 8454/6500/5519/7311/5518/7316/1163/7314/6233/5515/5516 11 Newcastle_disease_virus R-HSA-69236 G1 Phase 11/528 44/10654 6.883104264467439e-6 2.4556739122413945e-5 1.1803657258422587e-5 8454/6500/5519/7311/5518/7316/1163/7314/6233/5515/5516 11 Newcastle_disease_virus R-HSA-73886 Chromosome Maintenance 18/528 110/10654 6.90257348372973e-6 2.4556739122413945e-5 1.1803657258422587e-5 79172/5928/55839/23421/2491/79682/55355/64105/55320/1060/91687/1058/64946/401541/79019/80152/5111/55166 18 Newcastle_disease_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 6/528 12/10654 1.0304085310212294e-5 3.638748945340651e-5 1.7490329308847437e-5 7311/7316/29110/7314/6233/10010 6 Newcastle_disease_virus R-HSA-9634600 Regulation of glycolysis by fructose 2,6-bisphosphate metabolism 6/528 12/10654 1.0304085310212294e-5 3.638748945340651e-5 1.7490329308847437e-5 5519/5518/5528/5515/5566/5516 6 Newcastle_disease_virus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 10/528 38/10654 1.1031476582538406e-5 3.8812952534886966e-5 1.8656173632234068e-5 348995/79023/57122/5903/6396/55746/8480/23279/4193/79902 10 Newcastle_disease_virus R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 9/528 31/10654 1.274690498042735e-5 4.435922933188718e-5 2.1322095603623932e-5 348995/79023/57122/5903/6396/55746/8480/23279/79902 9 Newcastle_disease_virus R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 9/528 31/10654 1.274690498042735e-5 4.435922933188718e-5 2.1322095603623932e-5 348995/79023/57122/5903/6396/55746/8480/23279/79902 9 Newcastle_disease_virus R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 9/528 31/10654 1.274690498042735e-5 4.435922933188718e-5 2.1322095603623932e-5 348995/79023/57122/5903/6396/55746/8480/23279/79902 9 Newcastle_disease_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 11/528 47/10654 1.3653025973504629e-5 4.716947962687339e-5 2.267289511845534e-5 8454/6500/22938/7311/2033/7316/55294/3066/4609/7314/6233 11 Newcastle_disease_virus R-HSA-4570464 SUMOylation of RNA binding proteins 11/528 47/10654 1.3653025973504629e-5 4.716947962687339e-5 2.267289511845534e-5 1912/348995/79023/57122/5903/6396/55746/6045/8480/23279/79902 11 Newcastle_disease_virus R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 7/528 18/10654 1.3923467082392195e-5 4.793078416492565e-5 2.3038830424102193e-5 2033/995/891/7157/983/6790/5111 7 Newcastle_disease_virus R-HSA-948021 Transport to the Golgi and subsequent modification 24/528 185/10654 1.4122821173665853e-5 4.844279520859578e-5 2.3284938135793163e-5 8615/5861/81876/7277/10381/10383/7846/1780/6396/11258/1781/1453/64689/1783/51143/8655/10540/1639/140735/23243/2801/10382/10121/1778 24 Newcastle_disease_virus R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 10/528 39/10654 1.4185302885728436e-5 4.8483338791578975e-5 2.3304426169411002e-5 672/5932/472/7156/5888/11073/9156/1111/641/675 10 Newcastle_disease_virus R-HSA-5654741 Signaling by FGFR3 10/528 40/10654 1.8085202974122458e-5 6.137425264622409e-5 2.9500685702469257e-5 7311/5518/4893/3845/7316/3265/7314/6233/5515/5516 10 Newcastle_disease_virus R-HSA-6783310 Fanconi Anemia Pathway 10/528 40/10654 1.8085202974122458e-5 6.137425264622409e-5 2.9500685702469257e-5 146956/7311/84464/80198/2072/7316/79008/57697/7314/6233 10 Newcastle_disease_virus R-HSA-202670 ERKs are inactivated 6/528 13/10654 1.833616738965681e-5 6.17877189855689e-5 2.969942605366948e-5 5519/5518/5528/51231/5515/5516 6 Newcastle_disease_virus R-HSA-209560 NF-kB is activated and signals survival 6/528 13/10654 1.833616738965681e-5 6.17877189855689e-5 2.969942605366948e-5 7311/7316/3551/5970/7314/6233 6 Newcastle_disease_virus R-HSA-180746 Nuclear import of Rev protein 9/528 33/10654 2.2311471219524233e-5 7.465761523456186e-5 3.588558308035366e-5 348995/79023/57122/5903/6396/55746/8480/23279/79902 9 Newcastle_disease_virus R-HSA-180910 Vpr-mediated nuclear import of PICs 9/528 33/10654 2.2311471219524233e-5 7.465761523456186e-5 3.588558308035366e-5 348995/79023/57122/5903/6396/55746/8480/23279/79902 9 Newcastle_disease_virus R-HSA-5654743 Signaling by FGFR4 10/528 41/10654 2.2871746771107142e-5 7.626572006951057e-5 3.6658548831739665e-5 7311/5518/4893/3845/7316/3265/7314/6233/5515/5516 10 Newcastle_disease_virus R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 8/528 26/10654 2.4392795599374636e-5 8.10552270437553e-5 3.89607151934456e-5 672/5932/472/7156/5888/9156/641/675 8 Newcastle_disease_virus R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 10/528 42/10654 2.8705177895827376e-5 9.505486244396816e-5 4.5689902533150845e-5 672/5932/472/7156/5888/11073/9156/1111/641/675 10 Newcastle_disease_virus R-HSA-159227 Transport of the SLBP independent Mature mRNA 9/528 34/10654 2.9025533775800087e-5 9.578426146014028e-5 4.60405018512691e-5 348995/79023/57122/5903/6396/55746/8480/23279/79902 9 Newcastle_disease_virus R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 6/528 14/10654 3.0748021319088636e-5 1.0111978145143582e-4 4.860511961093049e-5 7161/332/7159/9540/7157/8626 6 Newcastle_disease_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 7/528 20/10654 3.109496527687495e-5 1.0191055400674427e-4 4.89852192717893e-5 7311/8517/7316/3551/7321/7314/6233 7 Newcastle_disease_virus R-HSA-70326 Glucose metabolism 15/528 91/10654 3.660066736896886e-5 1.1954552447816791e-4 5.746179859974633e-5 5519/348995/79023/5518/57122/5903/6396/5528/55746/8480/23279/5515/79902/5566/5516 15 Newcastle_disease_virus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 9/528 35/10654 3.737638615864839e-5 1.2125153069093732e-4 5.828182248467206e-5 348995/79023/57122/5903/6396/55746/8480/23279/79902 9 Newcastle_disease_virus R-HSA-8953750 Transcriptional Regulation by E2F6 9/528 35/10654 3.737638615864839e-5 1.2125153069093732e-4 5.828182248467206e-5 672/5932/5928/5888/8726/1111/8317/6045/6241 9 Newcastle_disease_virus R-HSA-4551638 SUMOylation of chromatin organization proteins 13/528 71/10654 3.8658295079237407e-5 1.2498644726631822e-4 6.007708019070677e-5 1912/348995/79023/57122/5903/6396/3066/23314/55746/6045/8480/23279/79902 13 Newcastle_disease_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 7/528 21/10654 4.46625458317185e-5 1.4391264767998183e-4 6.917431340939566e-5 4893/3845/2033/3265/5058/5970/5566 7 Newcastle_disease_virus R-HSA-176033 Interactions of Vpr with host cellular proteins 9/528 36/10654 4.7672488244486026e-5 1.530958766777622e-4 7.358840467269654e-5 348995/79023/57122/5903/6396/55746/8480/23279/79902 9 Newcastle_disease_virus R-HSA-937039 IRAK1 recruits IKK complex 6/528 15/10654 4.910812922230401e-5 1.566549322191498e-4 7.529913147419949e-5 7311/8517/7316/3551/7314/6233 6 Newcastle_disease_virus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 6/528 15/10654 4.910812922230401e-5 1.566549322191498e-4 7.529913147419949e-5 7311/8517/7316/3551/7314/6233 6 Newcastle_disease_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 13/528 73/10654 5.241253467541826e-5 1.6664051722383813e-4 8.009889020163587e-5 22938/7514/7311/9110/7316/5501/7321/9958/10273/5500/4609/7314/6233 13 Newcastle_disease_virus R-HSA-5685938 HDR through Single Strand Annealing (SSA) 9/528 37/10654 6.026327766788988e-5 1.9096674413301529e-4 9.179174744115675e-5 672/5932/472/7156/5888/11073/2072/9156/641 9 Newcastle_disease_virus R-HSA-113510 E2F mediated regulation of DNA replication 7/528 22/10654 6.272645295095208e-5 1.9681709991495455e-4 9.460383068012445e-5 5519/23595/5518/891/983/5515/5516 7 Newcastle_disease_virus R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 7/528 22/10654 6.272645295095208e-5 1.9681709991495455e-4 9.460383068012445e-5 351/994/995/2309/7531/993/2801 7 Newcastle_disease_virus R-HSA-8863678 Neurodegenerative Diseases 7/528 22/10654 6.272645295095208e-5 1.9681709991495455e-4 9.460383068012445e-5 351/994/995/2309/7531/993/2801 7 Newcastle_disease_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 11/528 55/10654 6.542432686423589e-5 2.0461137519305146e-4 9.835029528610624e-5 7311/351/8517/598/7316/1540/3551/5970/10910/7314/6233 11 Newcastle_disease_virus R-HSA-193639 p75NTR signals via NF-kB 6/528 16/10654 7.529703959783224e-5 2.3472073907206988e-4 1.1282292578176818e-4 7311/7316/3551/5970/7314/6233 6 Newcastle_disease_virus R-HSA-114452 Activation of BH3-only proteins 8/528 30/10654 7.666100593469435e-5 2.3819669701137172e-4 1.1449371016220583e-4 7161/7159/7531/8655/7157/7532/8626/140735 8 Newcastle_disease_virus R-HSA-446203 Asparagine N-linked glycosylation 31/528 304/10654 1.0562745325466486e-4 3.271374523129912e-4 1.5724475241794768e-4 8615/5861/81876/7311/7277/10381/10383/7846/1780/6396/11258/1781/7316/2720/1453/64689/1783/5700/51143/8655/10540/1639/140735/23243/2801/10382/7314/10121/6233/7415/1778 31 Newcastle_disease_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 11/528 58/10654 1.0879565625300684e-4 3.3158421348448264e-4 1.5938217158083804e-4 8454/6500/22938/7311/2033/7316/55294/3066/4609/7314/6233 11 Newcastle_disease_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 11/528 58/10654 1.0879565625300684e-4 3.3158421348448264e-4 1.5938217158083804e-4 8454/6500/22938/7311/2033/7316/55294/3066/4609/7314/6233 11 Newcastle_disease_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 11/528 58/10654 1.0879565625300684e-4 3.3158421348448264e-4 1.5938217158083804e-4 8454/6500/22938/7311/2033/7316/55294/3066/4609/7314/6233 11 Newcastle_disease_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 11/528 58/10654 1.0879565625300684e-4 3.3158421348448264e-4 1.5938217158083804e-4 8454/6500/22938/7311/2033/7316/55294/3066/4609/7314/6233 11 Newcastle_disease_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 11/528 58/10654 1.0879565625300684e-4 3.3158421348448264e-4 1.5938217158083804e-4 8454/6500/22938/7311/2033/7316/55294/3066/4609/7314/6233 11 Newcastle_disease_virus R-HSA-177929 Signaling by EGFR 10/528 49/10654 1.1725440921571473e-4 3.562300622839333e-4 1.7122866107691673e-4 7311/58513/4893/1956/3845/7316/3265/998/7314/6233 10 Newcastle_disease_virus R-HSA-5626467 RHO GTPases activate IQGAPs 8/528 32/10654 1.2620141645583812e-4 3.8099291971052706e-4 1.8313139296430767e-4 7277/10381/10383/7846/6249/1499/998/10382 8 Newcastle_disease_virus R-HSA-69190 DNA strand elongation 8/528 32/10654 1.2620141645583812e-4 3.8099291971052706e-4 1.8313139296430767e-4 4172/4173/8318/4174/4175/5111/4176/4171 8 Newcastle_disease_virus R-HSA-1227986 Signaling by ERBB2 10/528 50/10654 1.4017344466494408e-4 4.2052033399483224e-4 2.021309860372234e-4 7311/4893/1956/3320/3845/7316/3265/10273/7314/6233 10 Newcastle_disease_virus R-HSA-5654736 Signaling by FGFR1 10/528 50/10654 1.4017344466494408e-4 4.2052033399483224e-4 2.021309860372234e-4 7311/5518/4893/3845/7316/3265/7314/6233/5515/5516 10 Newcastle_disease_virus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 9/528 41/10654 1.4215923140820777e-4 4.251449514301714e-4 2.0435389514929868e-4 348995/79023/57122/5903/6396/55746/8480/23279/79902 9 Newcastle_disease_virus R-HSA-388841 Costimulation by the CD28 family 12/528 70/10654 1.481172252883587e-4 4.4158312959800404e-4 2.1225521380886293e-4 5519/5518/5528/5525/5529/5058/998/5526/253260/5527/5515/5516 12 Newcastle_disease_virus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 7/528 25/10654 1.5527420037491214e-4 0.00046005390018201523 2.211335361376458e-4 5519/5518/5528/9261/51231/5515/5516 7 Newcastle_disease_virus R-HSA-937041 IKK complex recruitment mediated by RIP1 7/528 25/10654 1.5527420037491214e-4 0.00046005390018201523 2.211335361376458e-4 7311/8517/7316/3551/7321/7314/6233 7 Newcastle_disease_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 8/528 33/10654 1.5944619893145886e-4 4.7095682832532757e-4 2.2637423305083666e-4 7311/351/8517/7316/3551/5970/7314/6233 8 Newcastle_disease_virus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 6/528 18/10654 1.6031947008645882e-4 4.720791780699726e-4 2.2691371150698782e-4 7311/7316/29110/7314/6233/10010 6 Newcastle_disease_virus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 9/528 42/10654 1.7310124600249335e-4 5.081530442465833e-4 2.442532919053587e-4 348995/79023/57122/5903/6396/55746/8480/23279/79902 9 Newcastle_disease_virus R-HSA-5689877 Josephin domain DUBs 5/528 12/10654 1.7374083003191074e-4 5.084708695429315e-4 2.4440606059534847e-4 7311/7316/7314/6233/7415 5 Newcastle_disease_virus R-HSA-180024 DARPP-32 events 7/528 26/10654 2.034936652922137e-4 5.937299929410015e-4 2.8538745742200697e-4 5519/5518/5528/5577/5515/5566/5516 7 Newcastle_disease_virus R-HSA-168325 Viral Messenger RNA Synthesis 9/528 43/10654 2.0945439127256833e-4 6.092639892031852e-4 2.9285416408930524e-4 348995/79023/57122/5903/6396/55746/8480/23279/79902 9 Newcastle_disease_virus R-HSA-110320 Translesion Synthesis by POLH 6/528 19/10654 2.2457074331163547e-4 6.512551556037429e-4 3.130380058283403e-4 7311/7316/5111/7314/6233/7415 6 Newcastle_disease_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 11/528 63/10654 2.351022141822839e-4 6.797366132098056e-4 3.26728152640032e-4 7311/8517/5591/2033/7316/1499/3551/5970/29110/7314/6233 11 Newcastle_disease_virus R-HSA-209543 p75NTR recruits signalling complexes 5/528 13/10654 2.708687441833196e-4 7.807873138055326e-4 3.753000672419488e-4 7311/7316/3551/7314/6233 5 Newcastle_disease_virus R-HSA-5689901 Metalloprotease DUBs 8/528 37/10654 3.7221594935944036e-4 0.0010693213389569517 5.139893583283153e-4 672/7311/2033/29086/7316/10213/7314/6233 8 Newcastle_disease_virus R-HSA-5693606 DNA Double Strand Break Response 12/528 77/10654 3.732009688731681e-4 0.0010693213389569517 5.139893583283153e-4 672/9656/7158/7311/11200/3838/472/29086/7316/7157/7314/6233 12 Newcastle_disease_virus R-HSA-174490 Membrane binding and targetting of GAG proteins 5/528 14/10654 4.0426914577455986e-4 0.0011514451562686125 5.53463711477076e-4 7311/7251/7316/7314/6233 5 Newcastle_disease_virus R-HSA-174495 Synthesis And Processing Of GAG, GAGPOL Polyproteins 5/528 14/10654 4.0426914577455986e-4 0.0011514451562686125 5.53463711477076e-4 7311/7251/7316/7314/6233 5 Newcastle_disease_virus R-HSA-5654732 Negative regulation of FGFR3 signaling 7/528 29/10654 4.242097754999562e-4 0.0012010909915782782 5.773269134023071e-4 7311/5518/7316/7314/6233/5515/5516 7 Newcastle_disease_virus R-HSA-8863795 Downregulation of ERBB2 signaling 7/528 29/10654 4.242097754999562e-4 0.0012010909915782782 5.773269134023071e-4 7311/1956/3320/7316/10273/7314/6233 7 Newcastle_disease_virus R-HSA-1236394 Signaling by ERBB4 10/528 58/10654 4.986787194528964e-4 0.0014077744381015393 6.766731886381484e-4 1447/7311/4893/1956/3845/7316/3265/4734/7314/6233 10 Newcastle_disease_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 7/528 30/10654 5.299854879763393e-4 0.0014873786275465008 7.149364353933022e-4 7311/8517/7316/1540/3551/7314/6233 7 Newcastle_disease_virus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 7/528 30/10654 5.299854879763393e-4 0.0014873786275465008 7.149364353933022e-4 7311/11065/7316/7321/7324/7314/6233 7 Newcastle_disease_virus R-HSA-187037 Signaling by NTRK1 (TRKA) 12/528 80/10654 5.345720304878117e-4 0.0014958638396983502 7.190150117672321e-4 5519/5518/4893/4914/3845/5528/3265/9261/51231/5515/1785/5516 12 Newcastle_disease_virus R-HSA-198753 ERK/MAPK targets 6/528 22/10654 5.438293776895226e-4 0.0015129206815374218 7.272137027243615e-4 5519/5518/5528/51231/5515/5516 6 Newcastle_disease_virus R-HSA-9613829 Chaperone Mediated Autophagy 6/528 22/10654 5.438293776895226e-4 0.0015129206815374218 7.272137027243615e-4 7311/5116/3320/7316/7314/6233 6 Newcastle_disease_virus R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 5/528 15/10654 5.818496540506857e-4 0.0016046977490677414 7.713280716522058e-4 7311/7316/29110/7314/6233 5 Newcastle_disease_virus R-HSA-5637810 Constitutive Signaling by EGFRvIII 5/528 15/10654 5.818496540506857e-4 0.0016046977490677414 7.713280716522058e-4 4893/1956/3320/3845/3265 5 Newcastle_disease_virus R-HSA-5637812 Signaling by EGFRvIII in Cancer 5/528 15/10654 5.818496540506857e-4 0.0016046977490677414 7.713280716522058e-4 4893/1956/3320/3845/3265 5 Newcastle_disease_virus R-HSA-9012852 Signaling by NOTCH3 9/528 49/10654 5.855711162274389e-4 0.001610320569625457 7.74030785817879e-4 22938/7311/1956/10460/9787/2033/7316/7314/6233 9 Newcastle_disease_virus R-HSA-182971 EGFR downregulation 7/528 31/10654 6.557210893445765e-4 0.0017878207478711104 8.593495757792171e-4 7311/58513/1956/7316/998/7314/6233 7 Newcastle_disease_virus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 7/528 31/10654 6.557210893445765e-4 0.0017878207478711104 8.593495757792171e-4 5519/5518/5528/9261/51231/5515/5516 7 Newcastle_disease_virus R-HSA-5654733 Negative regulation of FGFR4 signaling 7/528 31/10654 6.557210893445765e-4 0.0017878207478711104 8.593495757792171e-4 7311/5518/7316/7314/6233/5515/5516 7 Newcastle_disease_virus R-HSA-5696400 Dual Incision in GG-NER 8/528 41/10654 7.736738485027321e-4 0.002103425775616803 0.0010110510520206157 7311/9557/2072/7316/5111/7314/6233/8451 8 Newcastle_disease_virus R-HSA-110312 Translesion synthesis by REV1 5/528 16/10654 8.121008424383492e-4 0.0021892408625732397 0.001052299683159551 7311/7316/5111/7314/6233 5 Newcastle_disease_virus R-HSA-175474 Assembly Of The HIV Virion 5/528 16/10654 8.121008424383492e-4 0.0021892408625732397 0.001052299683159551 7311/7251/7316/7314/6233 5 Newcastle_disease_virus R-HSA-205043 NRIF signals cell death from the nucleus 5/528 16/10654 8.121008424383492e-4 0.0021892408625732397 0.001052299683159551 7311/23421/7316/7314/6233 5 Newcastle_disease_virus R-HSA-1980143 Signaling by NOTCH1 11/528 73/10654 8.685249711166324e-4 0.0023347707790972393 0.0011222513671731765 8454/6500/22938/7311/2033/7316/55294/3066/4609/7314/6233 11 Newcastle_disease_virus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 6/528 24/10654 9.014787336710252e-4 0.0024098188495060647 0.0011583246298566246 7311/8517/7316/9261/7314/6233 6 Newcastle_disease_virus R-HSA-933542 TRAF6 mediated NF-kB activation 6/528 24/10654 9.014787336710252e-4 0.0024098188495060647 0.0011583246298566246 351/7706/8517/3551/5970/57506 6 Newcastle_disease_virus R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 8/528 42/10654 9.149850490910244e-4 0.002439110562618692 0.0011724042411751289 7514/7311/8945/1487/7316/1499/7314/6233 8 Newcastle_disease_virus R-HSA-5357905 Regulation of TNFR1 signaling 7/528 33/10654 9.77516705128568e-4 0.0025913669994682537 0.0012455891533494218 7311/8517/7316/1540/3551/7314/6233 7 Newcastle_disease_virus R-HSA-5654726 Negative regulation of FGFR1 signaling 7/528 33/10654 9.77516705128568e-4 0.0025913669994682537 0.0012455891533494218 7311/5518/7316/7314/6233/5515/5516 7 Newcastle_disease_virus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 4/528 10/10654 9.858325141875442e-4 0.0026061925858493914 0.0012527153495200836 7311/7316/7314/6233 4 Newcastle_disease_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 9/528 53/10654 0.0010592457007782615 0.002777255166150127 0.0013349397872821926 7161/598/7159/7531/8655/7157/7532/8626/140735 9 Newcastle_disease_virus R-HSA-191859 snRNP Assembly 9/528 53/10654 0.0010592457007782615 0.002777255166150127 0.0013349397872821926 348995/79023/57122/5903/6396/55746/8480/23279/79902 9 Newcastle_disease_virus R-HSA-194441 Metabolism of non-coding RNA 9/528 53/10654 0.0010592457007782615 0.002777255166150127 0.0013349397872821926 348995/79023/57122/5903/6396/55746/8480/23279/79902 9 Newcastle_disease_virus R-HSA-5696395 Formation of Incision Complex in GG-NER 8/528 43/10654 0.0010762491994495275 0.0028141270051180267 0.0013526629282698977 7311/9557/2072/7316/1069/7314/6233/8451 8 Newcastle_disease_virus R-HSA-5655862 Translesion synthesis by POLK 5/528 17/10654 0.001104009192446645 0.002871023905357172 0.0013800114905583062 7311/7316/5111/7314/6233 5 Newcastle_disease_virus R-HSA-5656121 Translesion synthesis by POLI 5/528 17/10654 0.001104009192446645 0.002871023905357172 0.0013800114905583062 7311/7316/5111/7314/6233 5 Newcastle_disease_virus R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus 6/528 25/10654 0.00113712227050138 0.0029491219860970745 0.0014175507979149993 7311/1956/10460/7316/7314/6233 6 Newcastle_disease_virus R-HSA-5654727 Negative regulation of FGFR2 signaling 7/528 34/10654 0.0011792051308823508 0.003049998135822729 0.0014660388113672468 7311/5518/7316/7314/6233/5515/5516 7 Newcastle_disease_virus R-HSA-8848021 Signaling by PTK6 9/528 54/10654 0.0012164466403495225 0.0031294070828346587 0.0015042082111848935 120892/7311/4893/1956/3845/7316/3265/7314/6233 9 Newcastle_disease_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 9/528 54/10654 0.0012164466403495225 0.0031294070828346587 0.0015042082111848935 120892/7311/4893/1956/3845/7316/3265/7314/6233 9 Newcastle_disease_virus R-HSA-5693565 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 11/528 76/10654 0.001222695794240173 0.003137050603452669 0.0015078822127358698 672/9656/7158/7311/11200/472/29086/7316/7157/7314/6233 11 Newcastle_disease_virus R-HSA-162599 Late Phase of HIV Life Cycle 16/528 139/10654 0.0014029691217190801 0.00358995039969294 0.0017255769946277455 7514/7311/5905/348995/79023/57122/5903/7251/6396/7316/55746/8480/23279/7314/6233/79902 16 Newcastle_disease_virus R-HSA-190840 Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane 5/528 18/10654 0.0014669667779697913 0.0037436992173789075 0.0017994792476429438 7277/10381/10383/7846/10382 5 Newcastle_disease_virus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 4/528 11/10654 0.0014887984157816456 0.003779257516984177 0.0018165710112985596 7311/7316/7314/6233 4 Newcastle_disease_virus R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 4/528 11/10654 0.0014887984157816456 0.003779257516984177 0.0018165710112985596 7311/7316/7314/6233 4 Newcastle_disease_virus R-HSA-9006936 Signaling by TGF-beta family members 13/528 102/10654 0.0015307738907599094 0.003875530723431834 0.0018628465337289903 22938/7514/7311/9110/7316/5501/7321/9958/10273/5500/4609/7314/6233 13 Newcastle_disease_virus R-HSA-168638 NOD1/2 Signaling Pathway 7/528 36/10654 0.001679384544501666 0.004240556752211331 0.002038303141083816 7311/8517/7316/1540/3551/7314/6233 7 Newcastle_disease_virus R-HSA-6784531 tRNA processing in the nucleus 9/528 57/10654 0.001803987838756762 0.004543200951816372 0.002183774752179238 348995/79023/57122/5903/6396/55746/8480/23279/79902 9 Newcastle_disease_virus R-HSA-190872 Transport of connexons to the plasma membrane 5/528 19/10654 0.0019106796474905592 0.004799266201177074 0.0023068573171802025 7277/10381/10383/7846/10382 5 Newcastle_disease_virus R-HSA-437239 Recycling pathway of L1 8/528 47/10654 0.001961573089164363 0.004914202739084543 0.002362103719936144 7277/10381/10383/24137/7846/285643/10382/1785 8 Norwalk_virus R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 109/1313 112/10654 2.1439623893201906e-96 2.6606573251463566e-93 1.2954046436524102e-93 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/1983/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 109 Norwalk_virus R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 108/1313 111/10654 1.8256524459063313e-95 1.1328173426848786e-92 5.5153921260538645e-93 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 108 Norwalk_virus R-HSA-72613 Eukaryotic Translation Initiation 111/1313 119/10654 5.2779726071628256e-92 1.6374910013722665e-89 7.972516517135427e-90 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/1983/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/1978/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 111 Norwalk_virus R-HSA-72737 Cap-dependent Translation Initiation 111/1313 119/10654 5.2779726071628256e-92 1.6374910013722665e-89 7.972516517135427e-90 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/1983/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/1978/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 111 Norwalk_virus R-HSA-72689 Formation of a pool of free 40S subunits 98/1313 101/10654 3.464765023336966e-86 8.599546787922349e-84 4.186894996621934e-84 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/8663/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 98 Norwalk_virus R-HSA-5620912 Anchoring of the basal body to the plasma membrane 95/1313 98/10654 2.063229153799987e-83 4.267445633109639e-81 2.0777079548792853e-81 115106/22995/55559/79867/11258/22981/8636/7531/10142/54903/80776/11190/203068/54801/7532/55125/1454/10382/85302/51134/95681/121441/7277/79441/5116/54806/9814/91147/5048/1781/23354/80321/8766/22832/146057/8655/9738/79598/983/1639/55722/4957/10121/9702/5566/79959/132320/347240/84131/7846/7840/7283/3320/22919/27077/22994/11064/4867/79600/10540/84902/10733/1069/4751/117177/5577/80254/57545/26005/54930/5518/26123/10383/55835/54820/5347/23322/9662/80184/55142/23332/1453/22897/9793/4218/5108/261734/8481/57787/93323/10806/51259/55755/9657/1778 95 Norwalk_virus R-HSA-168255 Influenza Life Cycle 115/1313 144/10654 1.9699205007964876e-78 3.4923876306977727e-76 1.7003524322664424e-76 6158/23165/3303/6138/6144/6203/5434/5903/6227/9349/4736/6206/6194/6234/6191/55706/7175/6166/6128/51121/6132/9631/6159/6147/6129/6217/6222/6176/6152/6136/6125/821/811/6224/6146/348995/51065/6154/6141/6202/79023/6123/57122/23636/6232/6134/6169/10762/6160/23511/6164/6155/6175/6218/53371/6209/6193/6173/23279/6210/4927/6231/6229/9688/11224/6205/6165/79902/6130/6142/6167/6204/9883/6228/23521/116832/23225/3320/140801/6156/6235/6143/6181/6124/6207/8086/6139/6233/7514/7311/6223/25873/9972/3921/6188/6189/8021/6135/6201/129401/6161/3304/9045/6187/55746/6168/6208/6157/6137/6170/200916/8480/6122/6133/6230 115 Norwalk_virus R-HSA-168273 Influenza Viral RNA Transcription and Replication 110/1313 134/10654 1.7436374475333308e-77 2.7048175904860794e-75 1.3169051248475422e-75 6158/23165/6138/6144/6203/5434/5903/6227/9349/4736/6206/6194/6234/6191/55706/7175/6166/6128/51121/6132/9631/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/348995/51065/6154/6141/6202/79023/6123/57122/23636/6232/6134/6169/10762/6160/23511/6164/6155/6175/6218/53371/6209/6193/6173/23279/6210/4927/6231/6229/9688/11224/6205/6165/79902/6130/6142/6167/6204/9883/6228/23521/116832/23225/3320/140801/6156/6235/6143/6181/6124/6207/8086/6139/6233/7311/6223/25873/9972/3921/6188/6189/8021/6135/6201/129401/6161/9045/6187/55746/6168/6208/6157/6137/6170/200916/8480/6122/6133/6230 110 Norwalk_virus R-HSA-168254 Influenza Infection 118/1313 155/10654 3.864781925710839e-76 5.329104855341278e-74 2.594602134921663e-74 6158/23165/3303/6138/6144/6203/5434/5903/6227/9349/4736/6206/6194/6234/6191/55706/7175/6166/6128/51121/6132/9631/6159/6147/6129/6217/6222/6176/6152/6136/8106/6125/821/811/6224/6146/348995/51065/6154/6141/9636/6202/79023/6123/57122/23636/6232/6134/6169/10762/6160/23511/6164/6155/6175/6218/53371/6209/6193/6173/23279/6210/4927/6231/6229/9688/11224/6205/6165/79902/6130/6142/6167/6204/9883/6228/23521/116832/23225/3320/140801/6156/6235/6143/6181/6124/6207/8086/6139/6233/7514/7311/6223/25873/9972/5610/3921/6188/6189/8021/6135/6201/129401/6161/3304/9045/6187/55746/6168/6208/6157/6137/6170/200916/8480/6122/6133/6230 118 Norwalk_virus R-HSA-156902 Peptide chain elongation 86/1313 89/10654 4.115134368479649e-75 5.1068817512832444e-73 2.4864075026392832e-73 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/1938/6159/6147/6129/1915/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 86 Norwalk_virus R-HSA-156842 Eukaryotic Translation Elongation 88/1313 93/10654 1.9893473923942487e-74 2.2443455581466023e-72 1.0927133045304295e-72 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/1938/6159/6147/6129/1915/6217/6222/6176/6152/6136/6125/1937/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/1933/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 88 Norwalk_virus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 89/1313 95/10654 3.4162333545964515e-74 3.5329546608784973e-72 1.7201034609985644e-72 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/6232/6134/6169/6160/6164/4686/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/1981/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/5976/6187/6168/22916/6208/6157/6137/6170/200916/6122/6133/6230 89 Norwalk_virus R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 80/1313 82/10654 5.46145646173657e-71 4.841191049296488e-69 2.3570496308547305e-69 114791/10844/115106/22995/55559/440145/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/653784/5048/1781/23354/728642/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/984/80097/10426/22994/11064/10540/10733/85378/1069/4751/5577/27175/80254/54930/5518/10383/55835/54820/5347/29922/9662/80184/55142/23332/1453/22897/27229/9793/5108/8481/93323/10806/55755/1778 80 Norwalk_virus R-HSA-380287 Centrosome maturation 80/1313 82/10654 5.46145646173657e-71 4.841191049296488e-69 2.3570496308547305e-69 114791/10844/115106/22995/55559/440145/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/653784/5048/1781/23354/728642/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/984/80097/10426/22994/11064/10540/10733/85378/1069/4751/5577/27175/80254/54930/5518/10383/55835/54820/5347/29922/9662/80184/55142/23332/1453/22897/27229/9793/5108/8481/93323/10806/55755/1778 80 Norwalk_virus R-HSA-192823 Viral mRNA Translation 84/1313 89/10654 8.717332031293211e-71 7.21213936722325e-69 3.511402516464774e-69 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 84 Norwalk_virus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 82/1313 88/10654 7.428311717098358e-68 5.761584275574414e-66 2.805165082641091e-66 8454/115106/8945/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/84962/55125/1454/10382/95681/6500/121441/7277/79441/9133/5116/9814/5048/1781/23354/7316/80321/8655/9738/983/1639/6790/55722/4957/10121/9702/5566/79959/84131/23291/7846/7840/7283/3320/22919/22994/11064/10540/10733/79866/1069/4751/5577/6233/80254/7311/54930/5518/10133/10383/55835/54820/5347/9662/80184/55142/23332/1453/22897/9793/4218/5108/8481/93323/10806/55755/7314/1778 82 Norwalk_virus R-HSA-2408557 Selenocysteine synthesis 84/1313 93/10654 1.239385919178291e-66 8.54487736500144e-65 4.160277880750521e-65 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 84 Norwalk_virus R-HSA-72764 Eukaryotic Translation Termination 84/1313 93/10654 1.239385919178291e-66 8.54487736500144e-65 4.160277880750521e-65 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 84 Norwalk_virus R-HSA-927802 Nonsense-Mediated Decay (NMD) 94/1313 115/10654 6.955859722361344e-66 4.316110957725214e-64 2.1014018319133746e-64 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/6232/6134/6169/6160/6164/4686/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/1981/140801/6156/6235/6143/6181/6124/6207/6139/6233/23381/7311/6223/25873/5518/3921/6188/6189/23293/9775/23049/6135/6201/6161/9045/5976/6187/6168/22916/6208/6157/6137/6170/200916/6122/6133/6230 94 Norwalk_virus R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 94/1313 115/10654 6.955859722361344e-66 4.316110957725214e-64 2.1014018319133746e-64 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/6232/6134/6169/6160/6164/4686/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/1981/140801/6156/6235/6143/6181/6124/6207/6139/6233/23381/7311/6223/25873/5518/3921/6188/6189/23293/9775/23049/6135/6201/6161/9045/5976/6187/6168/22916/6208/6157/6137/6170/200916/6122/6133/6230 94 Norwalk_virus R-HSA-8854518 AURKA Activation by TPX2 71/1313 73/10654 1.048669519680434e-62 6.1971374948734215e-61 3.0172245829401964e-61 115106/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/22974/10382/3161/95681/121441/7277/79441/5116/9814/5048/1781/23354/80321/8655/9738/983/1639/6790/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/22994/11064/10540/10733/1069/4751/5577/80254/54930/5518/10383/55835/54820/5347/9662/80184/55142/23332/1453/22897/9793/5108/8481/93323/10806/55755/1778 71 Norwalk_virus R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 82/1313 94/10654 3.1426482825191807e-62 1.7727393266392286e-60 8.631005330937848e-61 114791/10844/115106/4926/22995/55559/79861/440145/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/653784/5048/1781/23354/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/347733/3320/22919/80097/10426/22994/11064/10540/10733/85378/1069/4751/5577/27175/80254/54930/5518/10383/55835/54820/5347/29922/84790/9662/80184/55142/23332/1453/22897/27229/9793/5108/8481/93323/10806/55755/1778 82 Norwalk_virus R-HSA-380259 Loss of Nlp from mitotic centrosomes 68/1313 70/10654 5.934303144120039e-60 3.0685292507720705e-58 1.493986844177589e-58 115106/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/5048/1781/23354/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/22994/11064/10540/10733/1069/4751/5577/80254/54930/5518/10383/55835/54820/5347/9662/80184/55142/23332/1453/22897/9793/5108/8481/93323/10806/55755/1778 68 Norwalk_virus R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 68/1313 70/10654 5.934303144120039e-60 3.0685292507720705e-58 1.493986844177589e-58 115106/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/5048/1781/23354/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/22994/11064/10540/10733/1069/4751/5577/80254/54930/5518/10383/55835/54820/5347/9662/80184/55142/23332/1453/22897/9793/5108/8481/93323/10806/55755/1778 68 Norwalk_virus R-HSA-69275 G2/M Transition 119/1313 196/10654 3.0785472980501744e-59 1.5281908787521067e-57 7.44036273297179e-58 114791/10844/8454/115106/1017/8945/22995/55559/5684/79861/440145/2305/11258/22981/8636/7531/51512/10142/11190/5707/203068/54801/7532/84962/63943/55125/1454/22974/10382/3161/95681/6500/121441/7277/79441/9133/5116/9814/653784/5048/1781/23354/7316/728642/80321/8655/9738/983/1026/1639/6790/55722/4957/10121/9702/5566/79959/84131/5688/23291/7846/7840/7283/347733/3320/22919/984/5686/80097/2033/995/10426/5710/22994/11064/10540/7157/10733/85378/79866/1069/4751/5577/5704/6233/3326/27175/80254/5716/7514/7311/54930/5518/10133/10383/55835/54820/5347/29922/84790/9662/80184/55142/23332/1453/22897/7465/27229/9793/4218/5108/1022/8481/5693/93323/10806/55755/7314/1778 119 Norwalk_virus R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 88/1313 112/10654 6.4799289139214035e-59 3.0929199162217164e-57 1.5058620229112898e-57 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/1650/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6747/6169/6160/6164/6155/6748/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6185/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 88 Norwalk_virus R-HSA-453274 Mitotic G2-G2/M phases 119/1313 198/10654 1.5327577581029585e-58 7.045008806688043e-57 3.4300310064370306e-57 114791/10844/8454/115106/1017/8945/22995/55559/5684/79861/440145/2305/11258/22981/8636/7531/51512/10142/11190/5707/203068/54801/7532/84962/63943/55125/1454/22974/10382/3161/95681/6500/121441/7277/79441/9133/5116/9814/653784/5048/1781/23354/7316/728642/80321/8655/9738/983/1026/1639/6790/55722/4957/10121/9702/5566/79959/84131/5688/23291/7846/7840/7283/347733/3320/22919/984/5686/80097/2033/995/10426/5710/22994/11064/10540/7157/10733/85378/79866/1069/4751/5577/5704/6233/3326/27175/80254/5716/7514/7311/54930/5518/10133/10383/55835/54820/5347/29922/84790/9662/80184/55142/23332/1453/22897/7465/27229/9793/4218/5108/1022/8481/5693/93323/10806/55755/7314/1778 119 Norwalk_virus R-HSA-2262752 Cellular responses to stress 189/1313 479/10654 2.364081724081534e-54 1.047794792708994e-52 5.101439509860152e-53 1017/23165/818/3303/7014/3725/815/1019/5684/5903/79861/55706/7175/5241/11258/5606/64344/9631/9448/3159/112399/7531/1029/1915/1783/526/5707/389541/2146/84962/817/9550/7422/10382/9114/5594/93661/9530/3308/84335/1027/58528/10294/5925/55860/3091/830/7013/7277/348995/10013/50488/545/79023/57122/23636/3337/192670/3313/10808/153129/10671/1780/10762/847/23511/4306/1781/10312/7316/3305/53371/8655/527/6774/84516/1026/1639/9532/832/6667/2289/23279/4927/9688/10121/7415/6647/8994/79902/64223/4194/5598/9883/1432/2932/10524/5688/10325/7846/23225/3310/529/2908/8649/3309/347733/3320/5686/2033/1021/7266/6195/6009/5710/6767/51143/3301/816/7428/192669/10540/9531/7157/8453/6648/8086/10963/22824/57600/5609/10542/5704/6233/3326/2475/5716/55004/3306/51343/6196/7311/367/9972/538/2034/79400/10383/10670/23411/84790/8021/55662/6197/29882/5599/129401/5600/54583/3304/3312/523/201163/4217/26523/405/96459/3569/64121/3297/57521/55746/5693/10641/55466/140735/2288/5034/8480/10728/829/7314/51164/51182/28956/5595/4193/2950/1778 189 Norwalk_virus R-HSA-5663205 Infectious disease 165/1313 383/10654 1.4011506677543706e-53 5.9959585471833586e-52 2.91927580141927e-52 6804/6158/23165/3303/6138/8945/6144/6203/5434/1839/5684/5903/6227/9349/8065/4736/6206/6194/6234/6191/55706/7175/6166/6128/5606/51121/6132/9631/5604/1499/1938/3159/6159/6147/6129/6217/5707/6222/6176/6152/6136/8106/6125/4869/821/6500/811/6224/6146/348995/51065/6154/6141/9636/6202/79023/6123/57122/23636/6232/6134/6169/10762/6160/23511/6164/4686/7316/6155/6616/6175/6218/53371/920/292/4233/3055/6209/6193/6714/6173/23279/6210/4927/6231/6229/9688/11224/6205/6165/8731/79902/6130/6142/6167/6204/9883/867/5688/6228/23521/116832/23225/999/3320/5686/2534/140801/6156/6235/6143/5710/6181/6124/6207/8086/6139/5609/5704/6233/2885/3326/6844/5716/6843/7514/163/1025/9844/7311/6223/25873/9972/3932/5610/3921/6188/6189/8021/6135/6201/129401/6161/3304/6829/801/9045/6187/1022/5062/55746/6168/22916/5693/6208/6157/6137/6170/200916/8480/6122/6133/7314/5879/6230 165 Norwalk_virus R-HSA-376176 Signaling by ROBO receptors 119/1313 218/10654 3.1773249730328e-52 1.3143534305112348e-50 6.399243980774833e-51 6158/6138/6144/25/6092/23032/6203/5684/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/5707/5567/56924/6222/6176/6152/6136/5578/6125/6224/6146/51065/6154/6141/26986/6202/6123/6232/6134/6169/6160/8829/6164/4686/7316/6155/6175/6218/6209/6193/6714/6173/6210/6231/6229/11224/6205/6165/5566/6130/6142/6167/6204/5688/6228/23521/116832/5686/5063/1981/140801/6156/6235/6143/5710/6181/6124/998/8453/6207/6139/10487/6654/5704/6233/5716/7311/6223/25873/387/1630/3921/6188/6189/9775/6135/6201/6161/23332/5058/9045/6187/5062/6168/22916/5693/6208/6157/6137/6170/200916/6122/6133/7314/5879/6230 119 Norwalk_virus R-HSA-8953897 Cellular responses to external stimuli 189/1313 493/10654 4.541654239899818e-52 1.8181267457147338e-50 8.851984834303891e-51 1017/23165/818/3303/7014/3725/815/1019/5684/5903/79861/55706/7175/5241/11258/5606/64344/9631/9448/3159/112399/7531/1029/1915/1783/526/5707/389541/2146/84962/817/9550/7422/10382/9114/5594/93661/9530/3308/84335/1027/58528/10294/5925/55860/3091/830/7013/7277/348995/10013/50488/545/79023/57122/23636/3337/192670/3313/10808/153129/10671/1780/10762/847/23511/4306/1781/10312/7316/3305/53371/8655/527/6774/84516/1026/1639/9532/832/6667/2289/23279/4927/9688/10121/7415/6647/8994/79902/64223/4194/5598/9883/1432/2932/10524/5688/10325/7846/23225/3310/529/2908/8649/3309/347733/3320/5686/2033/1021/7266/6195/6009/5710/6767/51143/3301/816/7428/192669/10540/9531/7157/8453/6648/8086/10963/22824/57600/5609/10542/5704/6233/3326/2475/5716/55004/3306/51343/6196/7311/367/9972/538/2034/79400/10383/10670/23411/84790/8021/55662/6197/29882/5599/129401/5600/54583/3304/3312/523/201163/4217/26523/405/96459/3569/64121/3297/57521/55746/5693/10641/55466/140735/2288/5034/8480/10728/829/7314/51164/51182/28956/5595/4193/2950/1778 189 Norwalk_virus R-HSA-68877 Mitotic Prometaphase 112/1313 200/10654 1.0913006471456153e-50 4.23220032221159e-49 2.060547932439419e-49 114791/10844/115106/4926/22995/55559/5903/79861/54908/440145/11258/22981/25936/8636/7531/10142/80776/1459/55869/1783/11190/203068/54801/7532/55125/1454/10382/9212/95681/121441/1460/7277/348995/79441/79023/9133/57122/79980/5116/6232/332/1780/9814/653784/5885/5528/5048/1781/23354/80321/8655/9738/1457/983/1639/55722/4957/23279/10121/79902/9702/5566/79959/84131/7846/7840/7283/347733/3320/22919/80097/79003/11243/10426/22994/11064/51143/10540/10733/85378/1069/4751/5577/27175/80254/7514/54930/5518/10383/55835/54820/5347/29922/84790/9662/80184/55142/23332/1453/22897/25909/27229/9793/10726/5108/55746/8481/140735/93323/10806/55755/1778 112 Norwalk_virus R-HSA-2408522 Selenoamino acid metabolism 84/1313 118/10654 2.9024140666173535e-50 1.0914835929309503e-48 5.314148881143098e-49 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 84 Norwalk_virus R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 57/1313 59/10654 6.730985349193408e-50 2.4568096524555938e-48 1.1961565295470639e-48 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/8668/8667/6224/51065/8662/10480/26986/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/8665/6201/1978/6187/6208/1974/1968/6230 57 Norwalk_virus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 102/1313 171/10654 9.323337996092219e-50 3.305789272328698e-48 1.6095025593253936e-48 6158/6138/6144/6092/23032/6203/5684/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/5707/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/6232/6134/6169/6160/6164/4686/7316/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/5688/6228/23521/116832/5686/1981/140801/6156/6235/6143/5710/6181/6124/8453/6207/6139/5704/6233/5716/7311/6223/25873/3921/6188/6189/9775/6135/6201/6161/9045/6187/6168/22916/5693/6208/6157/6137/6170/200916/6122/6133/7314/6230 102 Norwalk_virus R-HSA-72649 Translation initiation complex formation 56/1313 58/10654 5.482076842168054e-49 1.8387182057109608e-47 8.952239281378274e-48 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/8668/8667/6224/51065/8662/10480/26986/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1974/1968/6230 56 Norwalk_virus R-HSA-72702 Ribosomal scanning and start codon recognition 56/1313 58/10654 5.482076842168054e-49 1.8387182057109608e-47 8.952239281378274e-48 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/1983/8668/8667/6224/51065/8662/10480/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1974/1968/6230 56 Norwalk_virus R-HSA-5617833 Cilium Assembly 108/1313 201/10654 1.6379892002434352e-46 5.349327888163429e-45 2.604448202049119e-45 115106/10694/22995/55559/79867/79861/11258/22981/8636/7531/10142/54903/80776/11190/203068/54801/7532/10575/55125/1454/10382/85302/51134/95681/121441/7277/79441/10013/26146/5116/54806/9814/91147/5048/1781/23354/10576/80321/8766/22832/146057/8655/9738/79598/983/1639/55722/4957/10121/9702/5566/79959/132320/347240/84131/6950/7846/7840/7283/347733/3320/22919/27077/22994/11064/4867/79600/10540/84902/10733/1069/4751/117177/5577/80254/57545/26005/54930/5518/26123/10383/55835/54820/5347/23322/84790/22948/378/9662/80184/55142/23332/1453/8195/22897/9793/4218/5108/261734/8481/57787/140735/93323/10806/51259/55755/9657/1778 108 Norwalk_virus R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 49/1313 51/10654 1.2549365224376648e-42 3.993272370115749e-41 1.944220145422995e-41 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/8668/8667/6224/51065/8662/10480/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/6204/8663/6228/8894/6235/6207/6233/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1968/6230 49 Norwalk_virus R-HSA-68886 M Phase 152/1313 395/10654 6.649741009121672e-42 2.0630821480799988e-40 1.0044608787462738e-40 114791/10844/4000/115106/23165/4926/22995/55559/5684/5903/79861/54908/440145/55706/7175/11258/5579/22981/9631/25936/8636/7531/10142/80776/1459/55869/1783/11190/5707/91754/203068/54801/7532/55125/1454/5578/10382/9212/5594/95681/5861/5925/121441/1460/7277/348995/79441/79023/9133/57122/23636/79980/5116/6232/332/1780/10762/9814/653784/5885/23511/5528/5048/1781/23354/7316/80321/53371/8655/9738/1457/983/1639/55722/4957/23279/4927/9688/10121/79902/9702/5566/79959/84131/81876/9883/5688/7846/23225/7840/7283/347733/3320/22919/5686/80097/79003/11243/10426/5710/22994/11064/51143/10540/10733/85378/1069/8086/4751/5577/5704/6233/27175/80254/5716/7514/7311/54930/9972/5518/10383/55835/54820/5347/29922/84790/8021/29882/129401/9662/80184/55142/23332/1453/22897/25909/27229/9793/10726/5108/55746/8481/7112/5693/140735/93323/10806/55755/8480/7314/5595/1778 152 Norwalk_virus R-HSA-3371556 Cellular response to heat stress 65/1313 89/10654 3.2061548234212675e-40 9.704483258209251e-39 4.7248597397787106e-39 23165/818/3303/815/5903/55706/7175/9631/7531/1915/817/5594/9530/3308/84335/348995/10013/545/79023/57122/23636/3337/3313/10808/10762/23511/3305/53371/9532/23279/4927/9688/7415/79902/64223/9883/2932/23225/3310/3309/3320/2033/7266/6767/816/9531/8086/22824/3326/2475/3306/9972/23411/8021/129401/3304/3312/3297/57521/55746/2288/8480/10728/51182/5595 65 Norwalk_virus R-HSA-72766 Translation 123/1313 291/10654 8.404961747214851e-39 2.48346607816515e-37 1.2091348478449437e-37 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/1938/6159/6147/8666/6129/1915/6217/6222/1650/1983/6176/6152/6136/8668/8667/6125/1937/7818/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/65003/6232/6134/6747/6169/6160/55699/6164/6155/6748/8661/6175/6218/9669/1933/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/1981/140801/6156/6235/6143/1973/6181/6124/6185/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/1978/6161/9045/6187/6168/6208/6157/6137/6170/7284/1974/200916/6122/6133/1968/6230 123 Norwalk_virus R-HSA-1852241 Organelle biogenesis and maintenance 122/1313 296/10654 3.770133815033494e-37 1.0880781545247829e-35 5.297568689912426e-36 115106/10694/5563/22995/55559/79867/79861/11258/22981/8636/7531/10142/54903/80776/11190/203068/54801/7532/10575/55125/1454/10382/85302/51134/95681/121441/7277/79441/10013/26146/5116/3313/54806/5465/9814/91147/5048/1781/23354/10576/80321/8766/22832/10989/146057/8655/9738/79598/54927/983/1639/84303/55722/4957/10121/9702/5566/79959/132320/347240/84131/1432/6950/7846/7840/7283/347733/3320/22919/27077/22994/11064/4867/79600/10540/84902/10733/6648/1069/4751/117177/5577/80254/57545/26005/54930/5518/26123/10383/1386/55835/54820/5347/23322/84790/22948/6742/378/5600/3054/9662/80184/55142/23332/1453/8195/22897/801/9793/4218/5108/261734/8481/57787/140735/93323/814/10806/51259/55755/9657/1778 122 Norwalk_virus R-HSA-4420097 VEGFA-VEGFR2 Pathway 65/1313 99/10654 1.1066525737918996e-35 3.1212632819903347e-34 1.5196616683171064e-34 5295/26999/5170/5590/4893/857/5290/5335/71/558/5579/1499/6461/5747/5567/10006/207/7422/10458/5578/3315/1793/10152/6714/64223/5566/8936/1432/10163/10810/10000/3320/55845/5063/2534/9475/3690/4846/3728/998/208/1398/5580/2475/23191/6093/3685/9844/2185/3791/387/3710/9564/3845/5600/3265/5058/801/3071/5062/63916/5829/10787/5879/253260 65 Norwalk_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 159/1313 473/10654 2.161917940189473e-35 5.962089252833636e-34 2.9027857255409537e-34 5295/26999/5170/5434/5590/1839/9252/4893/8065/6464/685/857/5290/3667/5335/71/558/5241/5579/4915/5604/1499/2065/6461/5747/5782/526/5567/10006/10273/207/9550/7422/10458/5578/9114/5594/2069/2322/3315/5908/2241/3178/23118/23385/2064/6778/2260/8829/5528/9306/1793/4686/10312/7316/673/1950/5753/527/6774/11059/5289/57498/4233/10152/6714/2099/64223/5566/8569/8936/5598/1432/2261/867/10163/5159/4067/3717/4914/529/10810/10000/145957/3320/3084/55845/2335/5063/2534/9475/3690/4846/6195/3728/8471/1445/1111/3630/998/2066/208/4145/6654/9542/6233/2885/7525/1398/10718/5580/2324/2475/23191/6093/3685/163/9844/6196/7311/3932/5518/2185/3791/387/3710/1956/8851/5581/9564/6197/3845/5600/2549/3265/523/5058/801/3071/1020/5062/3480/22916/5663/4486/5725/11140/51231/4916/7529/63916/5829/10787/7314/5879/253260/5595/2242/5607 159 Norwalk_virus R-HSA-194138 Signaling by VEGF 67/1313 107/10654 7.904037245095168e-35 2.1323717872093704e-33 1.038196196495338e-33 5295/26999/5170/5590/4893/857/5290/5335/71/558/5579/1499/6461/5747/5567/10006/207/7422/10458/5578/3315/8829/1793/10152/6714/64223/5566/8936/1432/10163/10810/10000/3320/55845/5063/2534/9475/3690/4846/3728/998/208/1398/5580/2324/2475/23191/6093/3685/9844/2185/3791/387/3710/9564/3845/5600/3265/5058/801/3071/5062/63916/5829/10787/5879/253260 67 Norwalk_virus R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 90/1313 185/10654 2.335687383617023e-34 6.167208602273885e-33 3.0026529858816825e-33 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/1454/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/25926/7311/6223/25873/83732/26168/3921/6188/6189/6135/6201/6161/1453/9045/6187/4691/6168/6208/6157/6137/6170/200916/6122/6133/6230 90 Norwalk_virus R-HSA-8868773 rRNA processing in the nucleus and cytosol 91/1313 195/10654 6.266795087693738e-33 1.6202276466308186e-31 7.888465746351331e-32 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/1454/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/1736/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/25926/7311/6223/25873/83732/26168/3921/6188/6189/6135/6201/6161/1453/9045/6187/4691/6168/6208/6157/6137/6170/200916/6122/6133/6230 91 Norwalk_virus R-HSA-1227986 Signaling by ERBB2 43/1313 50/10654 1.81362796841124e-32 4.593290426119079e-31 2.236353284356717e-31 5295/1839/4893/8065/6464/685/5290/5335/2065/5782/10273/207/5578/2069/2064/7316/1950/5753/6714/10000/145957/3320/3084/2534/2066/208/4145/6654/9542/6233/2885/7525/10718/5580/7311/387/1956/5581/3845/2549/3265/11140/7314 43 Norwalk_virus R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 45/1313 55/10654 5.236626172086162e-32 1.2997306159117853e-30 6.328049311110436e-31 3303/79861/5241/11258/1783/10382/93661/10294/55860/830/7277/3337/10671/1780/4306/1781/3305/8655/84516/1639/832/2289/10121/7846/2908/347733/3320/51143/3301/10540/10963/3326/3306/367/10383/84790/3304/3312/55466/140735/2288/10728/829/51164/1778 45 Norwalk_virus R-HSA-72312 rRNA processing 92/1313 205/10654 1.2766353151788026e-31 3.1064792669350863e-30 1.5124637170539378e-30 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/3028/6222/1454/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/1736/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/25926/7311/6223/25873/83732/26168/3921/6188/6189/6135/6201/6161/1453/9045/6187/4691/6168/6208/6157/6137/6170/200916/6122/6133/6230 92 Norwalk_virus R-HSA-9006925 Intracellular signaling by second messengers 115/1313 305/10654 9.174661129539612e-31 2.189568165722819e-29 1.0660436211246434e-29 5295/1147/818/5170/27161/3725/815/1839/5684/685/5290/3667/5335/5468/2065/5575/1459/842/5707/5567/389541/2146/817/10273/207/5578/5594/2069/84335/1027/7249/5582/58528/1460/2064/6199/192670/2260/153129/5573/5528/2100/7316/1950/1457/4233/1026/10645/6714/2099/64223/5566/84254/10014/2932/2261/5688/10325/5159/8649/10000/145957/3084/5686/2534/5728/6009/2444/5710/6615/816/3630/192669/3066/7157/1107/2066/5613/5987/3654/5371/208/9542/10542/5577/5704/6233/2885/10718/5580/2475/5716/55004/7311/3932/2931/5518/1386/10670/3710/1956/5581/2549/26523/801/64121/57521/5693/814/7314/5879/253260/28956/5595/4193 115 Norwalk_virus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 49/1313 69/10654 1.215619810665398e-29 2.8463852547844505e-28 1.3858307275510198e-28 23165/3303/5903/55706/7175/9631/7531/5594/9530/3308/348995/545/79023/57122/23636/3337/3313/10808/10762/23511/3305/53371/9532/23279/4927/9688/79902/9883/2932/23225/3310/3309/7266/6767/9531/8086/22824/3306/9972/23411/8021/129401/3304/3312/3297/55746/8480/51182/5595 49 Norwalk_virus R-HSA-1169408 ISG15 antiviral mechanism 50/1313 72/10654 1.751797972992919e-29 4.0258912675633566e-28 1.9601014356684907e-28 23165/5903/5335/55706/7175/9631/348995/9636/317649/79023/57122/23636/25820/1982/7706/10762/9470/23511/7316/53371/3434/23279/4927/9688/79902/23586/8672/9883/23225/1981/1973/3661/8086/9246/1977/51191/6233/3716/7311/9972/5610/8021/9775/129401/7334/55746/1974/8480/7314/5595 50 Norwalk_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 52/1313 80/10654 1.9181973427939937e-28 4.32815073164972e-27 2.1072636837583783e-27 23165/5903/5335/55706/7175/9631/2316/348995/9636/317649/79023/57122/23636/25820/1982/7706/10762/9470/23511/7316/53371/3434/23279/4927/9688/79902/23586/8672/9883/6059/23225/1981/1973/3661/8086/9246/1977/51191/6233/3716/7311/9972/5610/8021/9775/129401/7334/55746/1974/8480/7314/5595 52 Norwalk_virus R-HSA-5663202 Diseases of signal transduction 123/1313 377/10654 4.770264881841423e-26 1.057124771136644e-24 5.146864740934167e-25 5295/8454/4000/1147/27044/818/5170/815/5434/7276/1839/5684/4893/6464/685/5290/3667/5335/71/5604/1499/2065/10142/55869/842/5707/283455/8844/817/207/1452/5594/3280/2069/9530/84335/613/1027/7249/6500/5908/10013/23385/2064/23164/6199/2260/5528/2100/4686/7316/673/1950/6774/4233/9759/1026/6714/2099/4609/7415/64223/10014/22938/2932/2261/867/5688/5159/7046/3717/10000/145957/3320/3084/5686/2335/2534/2033/3690/408/55294/5728/1445/5710/11064/816/3066/4296/2066/5894/208/6654/9542/5704/6233/2885/10718/2475/5716/7048/7311/3932/2931/5518/1956/11160/3845/2549/3265/369/801/22916/5693/5663/11140/5245/7529/7314/5879/253260/5595/4193 123 Norwalk_virus R-HSA-8848021 Signaling by PTK6 39/1313 54/10654 2.8087525151703303e-24 6.009761847114448e-23 2.925996268072177e-23 120892/1017/1839/1019/4893/685/2065/207/2069/1027/3091/2064/1793/7316/1950/5753/6774/867/2908/145957/3084/595/2066/9542/6233/1398/10718/9844/7311/2034/387/1956/9564/3845/3265/63916/5829/7314/5879 39 Norwalk_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 39/1313 54/10654 2.8087525151703303e-24 6.009761847114448e-23 2.925996268072177e-23 120892/1017/1839/1019/4893/685/2065/207/2069/1027/3091/2064/1793/7316/1950/5753/6774/867/2908/145957/3084/595/2066/9542/6233/1398/10718/9844/7311/2034/387/1956/9564/3845/3265/63916/5829/7314/5879 39 Norwalk_virus R-HSA-1257604 PIP3 activates AKT signaling 95/1313 264/10654 8.867999936990698e-24 1.865286088441603e-22 9.081591371690742e-23 5295/1147/5170/27161/3725/1839/5684/685/5290/3667/5468/2065/1459/842/5707/389541/2146/10273/207/5594/2069/84335/1027/7249/58528/1460/2064/6199/192670/2260/153129/5528/2100/7316/1950/1457/4233/1026/6714/2099/64223/10014/2932/2261/5688/10325/5159/8649/10000/145957/3084/5686/2534/5728/6009/2444/5710/6615/3630/192669/3066/7157/1107/2066/5987/3654/5371/208/9542/10542/5704/6233/2885/10718/2475/5716/55004/7311/3932/2931/5518/1386/10670/1956/2549/26523/64121/57521/5693/7314/5879/253260/28956/5595/4193 95 Norwalk_virus R-HSA-913531 Interferon Signaling 79/1313 199/10654 4.6274787886967725e-23 9.571168627954492e-22 4.659952324056048e-22 23165/818/815/5903/51447/5335/55706/7175/9631/23321/4281/7412/2316/817/3123/348995/9636/317649/79023/57122/23636/25820/1982/7706/3126/2634/51127/10762/9470/23511/7316/3122/53371/3434/23279/4927/9688/3659/79902/23586/8672/9883/6059/3717/23225/1981/1973/3458/816/3661/8086/10346/9246/1977/5371/51191/6233/5580/684/3716/7311/9972/10107/5610/8021/9775/3127/3125/91543/129401/7334/6773/7297/55746/3660/1974/8480/7314/5595 79 Norwalk_virus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 30/1313 35/10654 6.86882341918931e-23 1.397411452985891e-21 6.803631825046875e-22 23165/5903/55706/7175/9631/7884/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/1977/9972/8021/129401/55746/22916/8480 30 Norwalk_virus R-HSA-159227 Transport of the SLBP independent Mature mRNA 29/1313 34/10654 4.873349097924695e-22 9.754558436329914e-21 4.7492400377059e-21 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/1977/9972/8021/129401/55746/22916/8480 29 Norwalk_virus R-HSA-3700989 Transcriptional Regulation by TP53 111/1313 365/10654 8.075131363111069e-21 1.5906727018445773e-19 7.74457043011822e-20 1017/834/2176/5170/27161/5563/3725/5434/8621/1329/5883/7531/1029/1459/389541/6446/8445/7532/207/1345/22974/9212/835/4849/1027/4869/7249/58528/4850/2810/1460/545/192670/7534/332/153129/9337/639/7316/84987/1457/983/1026/6790/641/25904/246175/64223/4194/112858/3364/1432/10524/4848/10325/56950/23019/843/8649/10000/6794/2033/995/10128/5728/6009/1111/192669/3066/7157/1107/5371/208/10542/6233/2475/55004/672/55571/1025/604/7311/839/5562/5518/1386/55835/10670/10419/8851/1340/1327/5600/57472/85456/6829/29883/26523/317/1020/133746/5810/64121/10397/1022/57521/7529/7314/253260/28956/4193 111 Norwalk_virus R-HSA-1250196 SHC1 events in ERBB2 signaling 22/1313 22/10654 8.49454728796349e-21 1.6471458100566704e-19 8.019523261991849e-20 1839/4893/6464/685/2065/5782/5578/2069/2064/1950/145957/3084/2066/6654/9542/2885/10718/5580/1956/5581/3845/3265 22 Norwalk_virus R-HSA-5683057 MAPK family signaling cascades 96/1313 294/10654 1.5975275963041462e-20 3.0500488415591467e-19 1.4849892150260408e-19 818/27161/3725/815/1839/5684/4893/6464/685/3667/71/5604/2065/5747/5707/283455/5567/8844/817/5594/2069/2322/3315/5908/2064/3337/192670/2260/5596/8452/5528/7316/673/1950/1852/4233/983/84078/6714/4609/5566/2261/5688/5159/3558/3717/8649/145957/3084/5686/2335/5063/2534/3690/408/1445/5710/816/192669/4296/998/2066/5894/5979/6654/9542/5704/6233/2885/10718/6709/3716/5716/7514/7311/5518/1956/5536/5896/1843/3845/3265/26523/5058/369/801/7297/3569/5062/5693/5245/7529/7314/5879/28956/5595 96 Norwalk_virus R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 27/1313 33/10654 1.171800646643425e-19 2.2033403067946826e-18 1.0727489173418278e-18 23165/3303/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/7514/9972/8021/129401/3304/55746/8480 27 Norwalk_virus R-HSA-166208 mTORC1-mediated signalling 22/1313 23/10654 1.7268251350044044e-19 3.1984925261797995e-18 1.557262572651262e-18 6194/389541/84335/58528/6198/153129/64223/10325/8649/1981/6009/1977/10542/1975/2475/55004/10670/1978/64121/57521/7529/28956 22 Norwalk_virus R-HSA-8863795 Downregulation of ERBB2 signaling 25/1313 29/10654 2.1963300787918807e-19 4.0083023937951826e-18 1.951537871867708e-18 1839/8065/685/2065/5782/10273/207/2069/2064/7316/1950/10000/145957/3320/3084/2066/208/4145/9542/6233/10718/7311/1956/11140/7314 25 Norwalk_virus R-HSA-449147 Signaling by Interleukins 126/1313 461/10654 3.928204272830321e-19 7.06507464142381e-18 3.439800537917017e-18 5295/8454/6804/1147/834/3725/8945/1326/596/5684/351/9252/1072/6464/5290/3667/6885/6597/5606/5604/4215/9049/11213/5782/7412/7184/5707/10392/207/5292/7422/29110/2625/5594/4582/821/6500/5908/3091/23118/8517/6778/7534/3313/332/5528/2357/1436/4313/7316/4985/6616/6175/79155/6774/920/3055/1026/4609/6647/5566/4988/5598/1432/867/5688/6950/3558/4067/3717/23291/836/3320/5686/4843/2335/2534/84867/3656/595/6195/5306/5710/3458/10454/998/7157/6648/3654/5609/6654/5704/6233/2885/7525/1398/6844/3716/5716/604/6196/7311/3932/5518/2185/6845/1386/5896/6197/5599/5600/4282/7334/3312/3551/6773/7297/3569/5062/4170/5693/5034/51231/829/7314/5595 126 Norwalk_virus R-HSA-450294 MAP kinase activation 38/1313 64/10654 4.135010299312821e-19 7.330782544924587e-18 3.569166784670015e-18 8454/1147/3725/8945/1326/9252/6885/5606/5604/10392/5594/6500/23118/8517/5528/7316/79155/5598/1432/23291/3656/6195/10454/3654/5609/6233/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595 38 Norwalk_virus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 30/1313 42/10654 9.806512915091384e-19 1.714067961637804e-17 8.345349760211202e-18 23165/5903/55706/7175/9631/7884/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/1977/9972/8021/129401/55746/22916/8480 30 Norwalk_virus R-HSA-165159 mTOR signalling 29/1313 40/10654 1.922160101783829e-18 3.3033060682005956e-17 1.608293552014201e-17 5563/6194/389541/207/84335/7249/58528/6198/153129/64223/10325/8649/6794/1981/6009/1977/208/10542/1975/2475/55004/5562/10670/92335/1978/64121/57521/7529/28956 29 Norwalk_virus R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 27/1313 35/10654 1.9431212165885857e-18 3.3033060682005956e-17 1.608293552014201e-17 23165/5903/55706/7175/9631/91754/348995/79023/9133/57122/23636/10762/23511/53371/983/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 27 Norwalk_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 46/1313 94/10654 3.014443371588612e-18 5.0553030055965774e-17 2.4612951568874304e-17 8454/1147/3725/11035/8945/1326/351/9252/6885/5606/5604/8737/10392/29110/5594/6500/23118/841/8517/5528/7316/79155/5598/1432/329/23291/3656/6195/10454/3661/3654/5609/6233/6196/7311/5518/1386/9641/6197/5599/5600/7334/3551/51231/7314/5595 46 Norwalk_virus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 28/1313 38/10654 3.68260039981462e-18 6.093476128226592e-17 2.9667545677103044e-17 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/7428/8086/5987/5371/9972/8021/129401/55746/8480/4193 28 Norwalk_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 19/1313 19/10654 4.725359857242321e-18 7.615807250438597e-17 3.7079378784102424e-17 5295/4893/6464/5290/5335/7316/1950/867/3320/6654/6233/2885/7311/1956/3845/2549/3265/11140/7314 19 Norwalk_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 19/1313 19/10654 4.725359857242321e-18 7.615807250438597e-17 3.7079378784102424e-17 5295/4893/6464/5290/5335/7316/1950/867/3320/6654/6233/2885/7311/1956/3845/2549/3265/11140/7314 19 Norwalk_virus R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 25/1313 31/10654 5.315100159609259e-18 8.456460638557808e-17 4.117230083152112e-17 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/7514/9972/8021/129401/55746/8480 25 Norwalk_virus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 29/1313 41/10654 5.800717188997586e-18 9.112265862716461e-17 4.4365245389535176e-17 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/1977/9972/8021/129401/55746/22916/8480 29 Norwalk_virus R-HSA-1643713 Signaling by EGFR in Cancer 22/1313 25/10654 1.3490758045256572e-17 2.0668755062735498e-16 1.0063077658942428e-16 5295/1839/4893/6464/685/5290/5335/2069/7316/1950/867/3320/6654/6233/2885/7311/1956/3845/2549/3265/11140/7314 22 Norwalk_virus R-HSA-429947 Deadenylation of mRNA 22/1313 25/10654 1.3490758045256572e-17 2.0668755062735498e-16 1.0063077658942428e-16 9924/5073/4849/4850/255967/26986/10605/9337/25904/246175/4848/23019/1981/1973/1977/1975/55571/9775/57472/85456/29883/1974 22 Norwalk_virus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 43/1313 86/10654 1.3657033965707581e-17 2.0668755062735498e-16 1.0063077658942428e-16 5295/26999/25/1072/3984/5290/5335/71/5747/10006/4627/10458/5594/2268/1793/3055/10152/6714/8936/10163/4067/10810/3320/55845/2534/998/695/8976/2885/7525/1398/3326/5580/23191/9844/3710/5581/5058/3071/63916/10787/5879/5595 43 Norwalk_virus R-HSA-166166 MyD88-independent TLR4 cascade 46/1313 99/10654 4.032280088975464e-17 5.957213798117322e-16 2.9004119938244567e-16 8454/1147/3725/11035/8945/1326/351/9252/6885/5606/5604/8737/10392/29110/5594/6500/23118/841/8517/5528/7316/79155/5598/1432/329/23291/3656/6195/10454/3661/3654/5609/6233/6196/7311/5518/1386/9641/6197/5599/5600/7334/3551/51231/7314/5595 46 Norwalk_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 46/1313 99/10654 4.032280088975464e-17 5.957213798117322e-16 2.9004119938244567e-16 8454/1147/3725/11035/8945/1326/351/9252/6885/5606/5604/8737/10392/29110/5594/6500/23118/841/8517/5528/7316/79155/5598/1432/329/23291/3656/6195/10454/3661/3654/5609/6233/6196/7311/5518/1386/9641/6197/5599/5600/7334/3551/51231/7314/5595 46 Norwalk_virus R-HSA-195258 RHO GTPase Effectors 96/1313 327/10654 5.440976327086187e-17 7.943825437545833e-16 3.8676413767770546e-16 26999/5170/25/5590/5903/1072/3984/79861/54908/71/5579/1499/25936/7531/5747/80776/1783/10006/4627/2316/7532/10458/5578/10382/9212/5594/3985/1027/1080/2810/7277/348995/79023/57122/79980/6232/7534/332/1780/5528/5048/1781/8655/5289/5585/10152/6714/23279/79902/8936/1432/10163/7846/999/10810/347733/22919/55845/5063/9475/995/79003/11243/51143/998/695/8976/2885/5580/23191/7514/6093/367/5518/10383/54820/5347/387/84790/5600/23332/25909/5058/801/3071/9793/10726/5586/5062/55746/140735/7529/10787/5879/5595/1778 96 Norwalk_virus R-HSA-2980766 Nuclear Envelope Breakdown 32/1313 52/10654 6.017709012239474e-17 8.683694051382776e-16 4.2278641040703287e-16 4000/23165/5903/55706/7175/5579/9631/91754/5578/348995/79023/9133/57122/23636/10762/23511/53371/983/23279/4927/9688/79902/9883/23225/8086/9972/5347/8021/129401/55746/7112/8480 32 Norwalk_virus R-HSA-180746 Nuclear import of Rev protein 25/1313 33/10654 7.824665565261128e-17 1.1034556780101204e-15 5.372437840263024e-16 23165/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 25 Norwalk_virus R-HSA-180910 Vpr-mediated nuclear import of PICs 25/1313 33/10654 7.824665565261128e-17 1.1034556780101204e-15 5.372437840263024e-16 23165/5903/55706/7175/9631/3159/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 25 Norwalk_virus R-HSA-448424 Interleukin-17 signaling 38/1313 72/10654 1.0073336001837111e-16 1.4046078627280736e-15 6.838669266770552e-16 8454/1147/3725/8945/1326/9252/6885/5606/5604/10392/5594/6500/23118/8517/5528/7316/79155/5598/1432/23291/3656/6195/10454/3654/5609/6233/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595 38 Norwalk_virus R-HSA-176033 Interactions of Vpr with host cellular proteins 26/1313 36/10654 1.3537348999741136e-16 1.8276850714993043e-15 8.898521829090298e-16 23165/5903/55706/7175/9631/3159/348995/79023/57122/23636/10762/23511/53371/292/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 26 Norwalk_virus R-HSA-177243 Interactions of Rev with host cellular proteins 26/1313 36/10654 1.3537348999741136e-16 1.8276850714993043e-15 8.898521829090298e-16 23165/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/7514/9972/8021/129401/55746/8480 26 Norwalk_virus R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 24/1313 31/10654 1.3843867584281594e-16 1.8276850714993043e-15 8.898521829090298e-16 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 24 Norwalk_virus R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 24/1313 31/10654 1.3843867584281594e-16 1.8276850714993043e-15 8.898521829090298e-16 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 24 Norwalk_virus R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 24/1313 31/10654 1.3843867584281594e-16 1.8276850714993043e-15 8.898521829090298e-16 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 24 Norwalk_virus R-HSA-165054 Rev-mediated nuclear export of HIV RNA 25/1313 34/10654 2.611869983481914e-16 3.4119269994747945e-15 1.6611782498821259e-15 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/7514/9972/8021/129401/55746/8480 25 Norwalk_virus R-HSA-168276 NS1 Mediated Effects on Host Pathways 27/1313 40/10654 5.345173627580857e-16 6.909750491487338e-15 3.3641772612186543e-15 23165/5903/55706/7175/9631/8106/348995/9636/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/5610/8021/129401/55746/8480 27 Norwalk_virus R-HSA-162909 Host Interactions of HIV factors 52/1313 129/10654 6.324266968076373e-16 8.091149801425546e-15 3.939369766332978e-15 23165/8945/5684/5903/8065/55706/7175/9631/3159/5707/4869/6500/348995/79023/57122/23636/10762/23511/7316/53371/920/292/3055/23279/4927/9688/79902/9883/5688/23225/5686/2534/5710/8086/5704/6233/5716/7514/163/1025/9844/7311/9972/3932/8021/129401/5062/55746/5693/8480/7314/5879 52 Norwalk_virus R-HSA-9607240 FLT3 Signaling 82/1313 267/10654 6.476080643293387e-16 8.124080029172275e-15 3.955402635179514e-15 5295/818/5170/815/1839/5684/4893/6464/685/5290/3667/71/5604/2065/5747/5707/283455/8844/817/5594/2069/2322/5908/2064/2260/8452/5528/7316/673/1950/1852/5289/4233/3055/84078/6714/2261/5688/5159/3558/3717/8649/145957/3084/5686/2335/2534/3690/408/1445/5710/816/4296/2066/5894/5979/208/6654/9542/5704/6233/2885/10718/6709/3716/5716/7311/5518/1956/5536/1843/3845/2549/3265/369/801/5693/5245/7529/7314/28956/5595 82 Norwalk_virus R-HSA-2219528 PI3K/AKT Signaling in Cancer 45/1313 101/10654 6.480934108686989e-16 8.124080029172275e-15 3.955402635179514e-15 5295/1147/5170/1839/685/5290/3667/2065/842/207/2069/84335/1027/7249/2064/6199/2260/2100/1950/4233/1026/6714/2099/64223/2932/2261/5159/10000/145957/3084/2534/5728/2066/208/9542/2885/10718/2475/3932/2931/1956/2549/5879/253260/4193 45 Norwalk_virus R-HSA-1963640 GRB2 events in ERBB2 signaling 16/1313 16/10654 2.6126282314134636e-15 3.178697681553047e-14 1.5476249791860972e-14 1839/4893/685/2069/2064/1950/145957/3084/2066/6654/9542/2885/10718/1956/3845/3265 16 Norwalk_virus R-HSA-1963642 PI3K events in ERBB2 signaling 16/1313 16/10654 2.6126282314134636e-15 3.178697681553047e-14 1.5476249791860972e-14 5295/1839/685/5290/2065/2069/2064/1950/145957/3084/2066/9542/2885/10718/1956/2549 16 Norwalk_virus R-HSA-399954 Sema3A PAK dependent Axon repulsion 16/1313 16/10654 2.6126282314134636e-15 3.178697681553047e-14 1.5476249791860972e-14 1072/3984/5361/10371/8829/55558/3320/5063/2534/91584/3326/5362/5058/5062/5879/2242 16 Norwalk_virus R-HSA-168253 Host Interactions with Influenza Factors 27/1313 42/10654 3.420880477285554e-15 4.1216627886518176e-14 2.0067300909166153e-14 23165/5903/55706/7175/9631/8106/348995/9636/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/5610/8021/129401/55746/8480 27 Norwalk_virus R-HSA-3371571 HSF1-dependent transactivation 20/1313 24/10654 3.734851414739341e-15 4.456683274703387e-14 2.1698428259720466e-14 818/3303/815/817/84335/3337/3305/64223/3320/2033/816/3326/2475/3306/3304/3312/3297/57521/2288/10728 20 Norwalk_virus R-HSA-5684996 MAPK1/MAPK3 signaling 78/1313 255/10654 4.34920018603749e-15 5.140340410354786e-14 2.5026976509128017e-14 818/815/1839/5684/4893/6464/685/3667/71/5604/2065/5747/5707/283455/8844/817/5594/2069/2322/5908/2064/2260/8452/5528/7316/673/1950/1852/4233/983/84078/6714/2261/5688/5159/3558/3717/8649/145957/3084/5686/2335/2534/3690/408/1445/5710/816/4296/2066/5894/5979/6654/9542/5704/6233/2885/10718/6709/3716/5716/7311/5518/1956/5536/1843/3845/3265/369/801/7297/3569/5693/5245/7529/7314/28956/5595 78 Norwalk_virus R-HSA-4085377 SUMOylation of SUMOylation proteins 24/1313 34/10654 4.764272758875387e-15 5.5777948054380714e-14 2.7156827841057324e-14 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 24 Norwalk_virus R-HSA-71291 Metabolism of amino acids and derivatives 100/1313 372/10654 7.481973732295296e-15 8.677691029699498e-14 4.2249413894121994e-14 6158/6138/6144/6203/5684/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/3028/5707/6222/57515/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/5688/6228/23521/116832/8604/5686/445/6999/140801/6156/6235/6143/5710/6181/6124/26227/6207/6139/5704/6233/5716/7311/6223/25873/10157/3921/6188/6189/29968/6135/6201/6161/9045/6187/6168/5693/6208/6157/6137/6170/200916/6122/6133/6230 100 Norwalk_virus R-HSA-9612973 Autophagy 48/1313 119/10654 8.162102512017321e-15 9.378860386493976e-14 4.566322457990198e-14 5563/65018/1459/1915/389541/9821/10452/7249/58528/1080/1460/10013/64419/5116/153129/7416/100188893/7316/8655/5289/1457/8678/6714/64223/8408/3920/10325/8649/3320/6009/55054/10542/6233/3326/2475/55004/9804/7311/5562/11345/10670/55626/3312/64121/57521/140735/7314/28956 48 Norwalk_virus R-HSA-438064 Post NMDA receptor activation events 38/1313 81/10654 1.5209347207741183e-14 1.7316330169547532e-13 8.430869432393473e-14 818/5170/5563/815/4893/79861/5575/5567/817/10382/5594/7277/5573/10645/6714/5566/84254/27330/7846/347733/3084/6195/4137/816/2066/5613/5577/6196/5562/10383/84790/6197/3845/3265/801/814/5879/5595 38 Norwalk_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 39/1313 85/10654 1.719776526961409e-14 1.9055738124634898e-13 9.277741790186551e-14 8454/1147/3725/8945/1326/351/9252/6885/5606/5604/10392/5594/6500/23118/8517/5528/7316/79155/5598/1432/23291/3656/6195/10454/3654/5609/6233/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595 39 Norwalk_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 39/1313 85/10654 1.719776526961409e-14 1.9055738124634898e-13 9.277741790186551e-14 8454/1147/3725/8945/1326/351/9252/6885/5606/5604/10392/5594/6500/23118/8517/5528/7316/79155/5598/1432/23291/3656/6195/10454/3654/5609/6233/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595 39 Norwalk_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 39/1313 85/10654 1.719776526961409e-14 1.9055738124634898e-13 9.277741790186551e-14 8454/1147/3725/8945/1326/351/9252/6885/5606/5604/10392/5594/6500/23118/8517/5528/7316/79155/5598/1432/23291/3656/6195/10454/3654/5609/6233/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595 39 Norwalk_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 51/1313 134/10654 1.9255858866104965e-14 2.1147363586580762e-13 1.0296099663851189e-13 5295/8454/1147/5170/3725/8945/5684/4893/6464/4773/5290/5335/6885/4772/5707/5594/6500/23118/8517/7316/5688/4067/23291/5588/5686/2534/5710/10454/695/5609/6654/5704/6233/2885/5716/3702/7311/3710/3845/5599/7334/3265/3551/5058/801/5062/5693/997/7314/5879/5595 51 Norwalk_virus R-HSA-5637810 Constitutive Signaling by EGFRvIII 15/1313 15/10654 2.1414292568573016e-14 2.3108814850086183e-13 1.1251079116119828e-13 5295/4893/6464/5290/5335/1950/867/3320/6654/2885/1956/3845/2549/3265/11140 15 Norwalk_virus R-HSA-5637812 Signaling by EGFRvIII in Cancer 15/1313 15/10654 2.1414292568573016e-14 2.3108814850086183e-13 1.1251079116119828e-13 5295/4893/6464/5290/5335/1950/867/3320/6654/2885/1956/3845/2549/3265/11140 15 Norwalk_virus R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 29/1313 51/10654 3.314369859903093e-14 3.545804307017016e-13 1.7263596184976187e-13 79861/11258/1783/10382/93661/55860/830/7277/10671/1780/5048/1781/22930/8655/84516/1639/832/25782/10121/7846/347733/51143/10540/10383/84790/140735/829/51164/1778 29 Norwalk_virus R-HSA-6807070 PTEN Regulation 52/1313 140/10654 3.407689099149431e-14 3.614480488926875e-13 1.759796259929621e-13 27161/3725/5684/5468/1459/5707/389541/2146/10273/207/5594/58528/1460/192670/153129/7316/1457/64223/10014/5688/10325/8649/10000/5686/5728/6009/2444/5710/6615/192669/3066/7157/1107/5987/5371/208/10542/5704/6233/2475/5716/55004/7311/1386/10670/26523/64121/57521/5693/7314/28956/5595 52 Norwalk_virus R-HSA-168638 NOD1/2 Signaling Pathway 24/1313 36/10654 3.551832783128462e-14 3.73544447784951e-13 1.818690470576037e-13 1147/834/6885/842/10392/835/23118/841/8517/7316/7128/1432/329/837/3656/10454/3654/6233/7311/5600/7334/1540/3551/7314 24 Norwalk_virus R-HSA-5673001 RAF/MAP kinase cascade 75/1313 249/10654 3.667614652530504e-14 3.824798137638954e-13 1.8621944365789557e-13 818/815/1839/5684/4893/6464/685/3667/71/5604/2065/5747/5707/283455/8844/817/5594/2069/2322/5908/2064/2260/8452/5528/7316/673/1950/1852/4233/84078/6714/2261/5688/5159/3558/3717/8649/145957/3084/5686/2335/2534/3690/408/1445/5710/816/4296/2066/5894/5979/6654/9542/5704/6233/2885/10718/6709/3716/5716/7311/5518/1956/5536/1843/3845/3265/369/801/5693/5245/7529/7314/28956/5595 75 Norwalk_virus R-HSA-4615885 SUMOylation of DNA replication proteins 27/1313 45/10654 4.1022038997899595e-14 4.242362533032783e-13 2.0654956477889797e-13 23165/5903/55706/7175/9631/9212/348995/79023/57122/23636/332/10762/23511/53371/6790/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 27 Norwalk_virus R-HSA-1632852 Macroautophagy 41/1313 95/10654 4.873896524103286e-14 4.917484216595266e-13 2.3941947837700353e-13 5563/65018/1459/389541/9821/10452/7249/58528/1460/64419/153129/7416/100188893/7316/8655/5289/1457/8678/6714/64223/8408/10325/8649/6009/55054/10542/6233/2475/55004/9804/7311/5562/11345/10670/55626/3312/64121/57521/140735/7314/28956 41 Norwalk_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 41/1313 95/10654 4.873896524103286e-14 4.917484216595266e-13 2.3941947837700353e-13 8454/1147/3725/8945/1326/351/9252/6885/5606/5604/11213/10392/5594/6500/23118/8517/5528/7316/79155/5598/1432/23291/3656/6195/10454/695/3654/5609/6233/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595 41 Norwalk_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 41/1313 95/10654 4.873896524103286e-14 4.917484216595266e-13 2.3941947837700353e-13 8454/1147/3725/8945/1326/351/9252/6885/5606/5604/11213/10392/5594/6500/23118/8517/5528/7316/79155/5598/1432/23291/3656/6195/10454/695/3654/5609/6233/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595 41 Norwalk_virus R-HSA-6798695 Neutrophil degranulation 117/1313 480/10654 7.215939704546082e-14 7.221759010759426e-13 3.51608606995709e-13 10450/5869/10694/8773/3303/1727/80331/7276/4893/8621/5284/9218/1938/1915/5707/5315/203068/8876/1650/823/79888/353189/5594/4680/2268/5908/127829/55860/1460/23385/55754/79980/4257/23317/326624/847/2357/10312/10576/6616/4718/4126/8895/8655/84061/527/5547/9545/154664/54918/7415/2548/1432/11010/3920/6836/9342/226/3310/5476/8904/8649/55832/968/3320/5686/158747/3728/25798/2444/1088/51143/10043/23200/150372/374395/10075/5878/2683/8566/10487/3326/5580/684/6709/55004/23191/6093/3916/3685/719/81567/10383/387/10396/9145/4282/51806/80184/2720/3304/3312/5660/2040/3071/8673/317/10970/401258/5663/4758/1654/967/5879/28956/2950/1778 117 Norwalk_virus R-HSA-191859 snRNP Assembly 29/1313 53/10654 1.2912904291651429e-13 1.2718185893602718e-12 6.192152935177878e-13 23165/6635/5903/55706/7175/9631/25929/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/8086/9972/10419/8021/129401/55746/22916/8480 29 Norwalk_virus R-HSA-194441 Metabolism of non-coding RNA 29/1313 53/10654 1.2912904291651429e-13 1.2718185893602718e-12 6.192152935177878e-13 23165/6635/5903/55706/7175/9631/25929/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/8086/9972/10419/8021/129401/55746/22916/8480 29 Norwalk_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 41/1313 98/10654 1.7441639790653784e-13 1.6744209066480423e-12 8.152318592102941e-13 8454/1147/3725/8945/1326/351/9252/6885/5606/5604/11213/10392/5594/6500/23118/8517/5528/7316/79155/5598/1432/23291/3656/6195/10454/695/3654/5609/6233/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595 41 Norwalk_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 41/1313 98/10654 1.7441639790653784e-13 1.6744209066480423e-12 8.152318592102941e-13 8454/1147/3725/8945/1326/351/9252/6885/5606/5604/11213/10392/5594/6500/23118/8517/5528/7316/79155/5598/1432/23291/3656/6195/10454/695/3654/5609/6233/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595 41 Norwalk_virus R-HSA-70171 Glycolysis 34/1313 71/10654 1.753058864539748e-13 1.6744209066480423e-12 8.152318592102941e-13 23165/5903/2597/55706/7175/9631/5315/5567/348995/79023/57122/23636/3099/10762/23511/5528/53371/5230/23279/4927/9688/79902/5566/9883/2023/226/23225/8086/9972/5518/8021/129401/55746/8480 34 Norwalk_virus R-HSA-1250347 SHC1 events in ERBB4 signaling 14/1313 14/10654 1.754026735408908e-13 1.6744209066480423e-12 8.152318592102941e-13 1839/4893/6464/685/2069/145957/3084/2066/6654/9542/2885/10718/3845/3265 14 Norwalk_virus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 27/1313 47/10654 1.8218437263168554e-13 1.6872448241486697e-12 8.214754901067362e-13 818/815/4893/71/5604/283455/8844/817/5594/5908/673/6714/3717/2335/3690/408/1445/816/4296/5894/3845/3265/369/801/5245/7529/5595 27 Norwalk_virus R-HSA-6802949 Signaling by RAS mutants 27/1313 47/10654 1.8218437263168554e-13 1.6872448241486697e-12 8.214754901067362e-13 818/815/4893/71/5604/283455/8844/817/5594/5908/673/6714/3717/2335/3690/408/1445/816/4296/5894/3845/3265/369/801/5245/7529/5595 27 Norwalk_virus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 27/1313 47/10654 1.8218437263168554e-13 1.6872448241486697e-12 8.214754901067362e-13 818/815/4893/71/5604/283455/8844/817/5594/5908/673/6714/3717/2335/3690/408/1445/816/4296/5894/3845/3265/369/801/5245/7529/5595 27 Norwalk_virus R-HSA-9649948 Signaling downstream of RAS mutants 27/1313 47/10654 1.8218437263168554e-13 1.6872448241486697e-12 8.214754901067362e-13 818/815/4893/71/5604/283455/8844/817/5594/5908/673/6714/3717/2335/3690/408/1445/816/4296/5894/3845/3265/369/801/5245/7529/5595 27 Norwalk_virus R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 31/1313 61/10654 2.663582897371768e-13 2.4485232412136035e-12 1.1921220920790606e-12 26999/25/1072/3984/71/5747/10006/4627/10458/5594/1793/10152/8936/10163/10810/3320/55845/998/695/8976/2885/1398/3326/23191/9844/5058/3071/63916/10787/5879/5595 31 Norwalk_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 48/1313 129/10654 3.0773605184088374e-13 2.8080914730480642e-12 1.3671864841847311e-12 8454/1147/3725/11035/8945/1326/351/9252/6885/5606/5604/11213/8737/10392/29110/5594/6500/23118/841/8517/5528/7316/79155/5598/1432/329/23291/3656/6195/10454/3661/695/3654/5609/6233/6196/7311/5518/1386/9641/6197/5599/5600/7334/3551/51231/7314/5595 48 Norwalk_virus R-HSA-1236394 Signaling by ERBB4 30/1313 58/10654 3.5372509377266224e-13 3.204181323882291e-12 1.5600322998502356e-12 5295/1839/4893/6464/685/5290/5241/2065/2069/23118/23385/7316/1950/11059/6714/2099/145957/3084/2066/6654/9542/6233/2885/10718/7311/1956/3845/3265/5663/7314 30 Norwalk_virus R-HSA-8951664 Neddylation 70/1313 234/10654 3.868385667355595e-13 3.478743922600213e-12 1.693709666714044e-12 8454/26224/54165/8945/5684/8065/64410/23038/64344/54850/142686/55884/5707/4738/9817/6500/3091/144699/26259/51130/332/8452/8450/9306/7316/84861/84078/26272/222235/10980/5688/55336/26270/6502/7347/23291/90864/55832/5686/55294/26190/5710/10987/7428/8453/9040/79176/80176/8139/126433/5704/6233/26267/5716/25793/7311/51666/2034/90293/8533/54461/127247/26268/115290/51725/140459/5693/51676/7314/8451 70 Norwalk_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 39/1313 92/10654 4.0913642864013937e-13 3.652793582319518e-12 1.778449905637562e-12 8454/1147/3725/8945/1326/351/9252/6885/5606/5604/10392/5594/6500/23118/8517/5528/7316/79155/5598/1432/23291/3656/6195/10454/3654/5609/6233/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595 39 Norwalk_virus R-HSA-389356 CD28 co-stimulation 22/1313 33/10654 4.2326455978113716e-13 3.751937990631366e-12 1.826720731687013e-12 5295/5170/1326/5290/207/9020/6714/64223/4067/10000/5063/2534/998/208/2885/7525/2475/3932/5058/5062/5879/253260 22 Norwalk_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 29/1313 55/10654 4.604370610130062e-13 4.052499239128657e-12 1.9730561629075447e-12 1147/834/596/351/6885/842/10392/10910/835/23118/841/8517/7316/7128/1432/329/837/3656/10454/3654/6233/3326/7311/114548/5600/7334/1540/3551/7314 29 Norwalk_virus R-HSA-9009391 Extra-nuclear estrogen signaling 35/1313 77/10654 5.411760679292776e-13 4.729573945776292e-12 2.3027061748806923e-12 5295/5170/596/5590/1839/4893/6464/685/857/5290/5747/207/5594/2069/1027/3315/2100/4313/1950/6714/2099/10000/3320/4846/595/2771/208/7514/1956/3845/858/3265/801/3480/5595 35 Norwalk_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 40/1313 97/10654 6.085485921249686e-13 5.281180439350252e-12 2.5712689869689513e-12 8454/1147/3725/8945/1326/351/9252/6885/5606/5604/10392/5594/6500/23118/8517/5528/7316/79155/5289/5598/1432/23291/3656/6195/10454/3654/5609/6233/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595 40 Norwalk_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 39/1313 93/10654 6.222043780739042e-13 5.325211263377346e-12 2.5927064465656702e-12 8454/1147/3725/8945/1326/351/9252/6885/5606/5604/10392/5594/6500/23118/8517/5528/7316/79155/5598/1432/23291/3656/6195/10454/3654/5609/6233/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595 39 Norwalk_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 39/1313 93/10654 6.222043780739042e-13 5.325211263377346e-12 2.5927064465656702e-12 8454/1147/3725/8945/1326/351/9252/6885/5606/5604/10392/5594/6500/23118/8517/5528/7316/79155/5598/1432/23291/3656/6195/10454/3654/5609/6233/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595 39 Norwalk_virus R-HSA-983169 Class I MHC mediated antigen processing & presentation 95/1313 371/10654 8.713045509639724e-13 7.406088683193765e-12 3.6058313788992084e-12 8454/1147/8773/26224/8945/5684/8065/64410/127544/55070/84708/54850/7319/142686/5707/10273/9817/6890/821/6500/811/144699/26259/51130/8517/8452/54778/7316/7317/84861/11059/84078/7337/26272/222235/55905/5688/10134/55336/9341/26270/6502/23291/10616/3309/5686/55521/55294/26190/55008/79654/5710/7428/22954/8453/9040/695/90933/63891/10075/9246/79176/80176/8139/51191/126433/5704/6233/9870/26267/5716/3685/25793/51343/7311/26091/6047/51666/90293/54461/29882/127247/7334/4591/3551/8673/26268/115290/90678/51725/140459/5693/997/51676/7314 95 Norwalk_virus R-HSA-5628897 TP53 Regulates Metabolic Genes 37/1313 86/10654 9.471664153270608e-13 7.99614640422369e-12 3.8931150905673685e-12 27161/5563/1329/7531/389541/7532/207/1345/7249/58528/2810/192670/7534/153129/84987/64223/10325/8649/10000/10128/5728/6009/192669/7157/208/10542/2475/55004/5562/10670/1340/1327/26523/64121/57521/7529/28956 37 Norwalk_virus R-HSA-168325 Viral Messenger RNA Synthesis 25/1313 43/10654 9.952346945664897e-13 8.345177405114957e-12 4.06304917980914e-12 23165/5434/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 25 Norwalk_virus R-HSA-8847993 ERBB2 Activates PTK6 Signaling 13/1313 13/10654 1.4357383454989336e-12 1.1958062327276354e-11 5.822068599903837e-12 1839/685/2065/2069/2064/1950/5753/145957/3084/2066/9542/10718/1956 13 Norwalk_virus R-HSA-4570464 SUMOylation of RNA binding proteins 26/1313 47/10654 1.7129518459656598e-12 1.417182160562256e-11 6.899890242696763e-12 23165/5903/55706/7175/9631/348995/79023/57122/23636/3183/10762/23511/53371/3190/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 26 Norwalk_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 58/1313 182/10654 2.2982709245083294e-12 1.8888438525263817e-11 9.196287979559297e-12 23165/5893/5903/55706/7175/5241/9631/5468/1029/8204/9212/4869/348995/79023/57122/23636/8517/332/3183/10762/5465/5885/23511/4306/53371/3190/9759/8856/6790/641/2099/23279/4927/9688/79902/9883/23225/2908/2033/7428/3066/7157/1107/1069/8086/5987/5371/672/367/9972/25942/8021/9641/129401/55746/8480/10062/4193 58 Norwalk_virus R-HSA-166520 Signaling by NTRKs 40/1313 101/10654 2.894677476126192e-12 2.3633518078109236e-11 1.1506543430030707e-11 5295/9252/4893/6464/5290/3667/5335/4915/5604/5594/5528/673/6774/57498/6714/5598/1432/4914/2534/6195/6654/2885/1398/163/6196/5518/387/8851/6197/3845/5600/2549/3265/1020/51231/4916/7529/5879/5595/5607 40 Norwalk_virus R-HSA-442755 Activation of NMDA receptors and postsynaptic events 38/1313 93/10654 3.2464449529672633e-12 2.6332275729623357e-11 1.2820498128677052e-11 818/5170/5563/815/4893/79861/5575/5567/817/10382/5594/7277/5573/10645/6714/5566/84254/27330/7846/347733/3084/6195/4137/816/2066/5613/5577/6196/5562/10383/84790/6197/3845/3265/801/814/5879/5595 38 Norwalk_virus R-HSA-168898 Toll-like Receptor Cascades 52/1313 155/10654 3.509620392419448e-12 2.828207082462685e-11 1.3769802496573914e-11 8454/1147/3725/11035/8945/1326/351/9252/6885/5606/5604/11213/7184/8737/10392/29110/5594/6271/6500/23118/841/8517/5528/7316/79155/5289/5598/1432/329/23291/3656/6195/10454/3661/695/3654/5609/6233/81622/6196/7311/5518/1386/9641/6197/5599/5600/7334/3551/51231/7314/5595 52 Norwalk_virus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 82/1313 309/10654 4.622615196541753e-12 3.701074489618268e-11 1.8019566199082968e-11 8454/26224/8945/5684/8065/64410/127544/55070/84708/54850/7319/142686/5707/10273/9817/6500/144699/26259/51130/8452/54778/7316/7317/84861/11059/84078/7337/26272/222235/55905/5688/55336/26270/6502/23291/10616/5686/55521/55294/26190/55008/79654/5710/7428/22954/8453/9040/90933/63891/10075/9246/79176/80176/8139/51191/126433/5704/6233/9870/26267/5716/25793/51343/7311/26091/6047/51666/90293/54461/29882/127247/7334/4591/26268/115290/90678/51725/140459/5693/997/51676/7314 82 Norwalk_virus R-HSA-70326 Glucose metabolism 37/1313 91/10654 7.48026501380839e-12 5.950646719318085e-11 2.8972146544709958e-11 23165/5903/2597/55706/7175/9631/5315/5567/348995/79023/57122/23636/3099/10762/6576/23511/5528/53371/5230/23279/4927/9688/79902/5566/9883/2023/226/23225/4190/8604/8086/9972/5518/8021/129401/55746/8480 37 Norwalk_virus R-HSA-2500257 Resolution of Sister Chromatid Cohesion 45/1313 126/10654 8.905495383522635e-12 7.039311956020122e-11 3.427257358459265e-11 5903/79861/54908/25936/80776/55869/1783/10382/9212/7277/348995/79023/9133/57122/79980/6232/332/1780/5885/5528/5048/1781/8655/983/23279/79902/7846/347733/22919/79003/11243/51143/7514/5518/10383/54820/5347/84790/23332/25909/9793/10726/55746/140735/1778 45 Norwalk_virus R-HSA-2990846 SUMOylation 58/1313 188/10654 1.0332735740385128e-11 8.115775350517686e-11 3.951359303784852e-11 23165/5893/5903/55706/7175/5241/9631/5468/1029/8204/9212/4869/348995/79023/57122/23636/8517/332/3183/10762/5465/5885/23511/4306/53371/3190/9759/8856/6790/641/2099/23279/4927/9688/79902/9883/23225/2908/2033/7428/3066/7157/1107/1069/8086/5987/5371/672/367/9972/25942/8021/9641/129401/55746/8480/10062/4193 58 Norwalk_virus R-HSA-187037 Signaling by NTRK1 (TRKA) 34/1313 80/10654 1.2063183274295867e-11 9.415352480126522e-11 4.584089506418953e-11 5295/9252/4893/6464/5290/3667/5335/4915/5604/5594/5528/673/6774/57498/6714/5598/1432/4914/6195/6654/2885/1398/163/6196/5518/387/6197/3845/5600/3265/51231/7529/5595/5607 34 Norwalk_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 14/1313 16/10654 1.652584525384494e-11 1.281785872501348e-10 6.240681036649341e-11 8454/1147/8945/1326/5604/6500/8517/7316/79155/23291/6233/7311/3551/7314 14 Norwalk_virus R-HSA-5621481 C-type lectin receptors (CLRs) 48/1313 142/10654 1.7622314825723748e-11 1.3583411614113773e-10 6.6134087675485e-11 8454/1147/5170/8945/5684/9252/4893/4773/6885/4772/5707/5567/4582/6500/23118/841/8517/7316/9020/6714/5566/5688/4067/23291/5686/5063/2534/2033/5710/10454/9040/5894/5704/6233/5580/5716/7311/3710/3845/7334/3265/3551/5058/801/5062/5693/997/7314 48 Norwalk_virus R-HSA-5357801 Programmed Cell Death 56/1313 181/10654 2.0784696986888724e-11 1.592210429674624e-10 7.752057225779161e-11 4000/11035/596/5684/1612/1499/7531/5747/1029/842/5707/8737/7532/207/5594/2810/841/7534/7316/8655/7082/6774/660/5688/10134/329/999/5588/836/10000/5686/8837/4137/5710/7157/197259/208/5704/6233/5580/6709/5716/6093/1613/7311/839/840/1630/5599/317/5062/5693/140735/7529/7314/5595 56 Norwalk_virus R-HSA-388841 Costimulation by the CD28 family 31/1313 70/10654 2.6761037095619634e-11 2.0374507383842922e-10 9.919816140061782e-11 5295/5170/1326/5290/207/3123/3126/5528/3122/9020/920/6714/64223/4067/10000/5063/2534/1445/998/208/2885/7525/2475/3932/5518/3127/3125/5058/5062/5879/253260 31 Norwalk_virus R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK 19/1313 29/10654 2.775163207120127e-11 2.0999863049000476e-10 1.0224285499916258e-10 5563/389541/7249/58528/153129/64223/10325/8649/6794/6009/10542/2475/55004/5562/10670/92335/64121/57521/28956 19 Norwalk_virus R-HSA-5673000 RAF activation 20/1313 32/10654 2.9700754000412234e-11 2.233856709970399e-10 1.0876065579736285e-10 818/815/4893/5604/8844/817/5528/673/6714/3717/816/4296/5894/5518/3845/3265/369/801/5245/7529 20 Norwalk_virus R-HSA-69620 Cell Cycle Checkpoints 77/1313 293/10654 3.5495563249645117e-11 2.653614095952385e-10 1.2919754790929803e-10 1017/4172/5684/5903/54908/5883/25936/7531/51512/1029/80776/1783/5707/7532/9212/1027/2810/348995/545/79023/9133/57122/79980/6232/7534/332/1780/5528/5048/1781/7316/4174/8655/983/1026/641/4171/23279/79902/4194/3364/10524/5688/22919/5686/995/79003/11243/5710/51143/1111/7157/5704/6233/5716/672/7514/23595/7311/5518/54820/5347/29882/7334/23332/7465/25909/9793/10726/5810/55746/5693/140735/7529/7314/4193/1778 77 Norwalk_virus R-HSA-6802957 Oncogenic MAPK signaling 31/1313 71/10654 4.1960732760181974e-11 3.11815984163987e-10 1.5181506841692063e-10 4000/27044/818/815/4893/71/5604/10142/283455/8844/817/5594/5908/23164/673/6714/3717/2335/3690/408/1445/816/4296/5894/3845/3265/369/801/5245/7529/5595 31 Norwalk_virus R-HSA-429914 Deadenylation-dependent mRNA decay 27/1313 56/10654 4.5239946518085395e-11 3.3418317636276176e-10 1.62705070810658e-10 1656/9924/80153/5073/27257/4849/4850/255967/26986/10605/9337/25904/246175/4848/23019/1981/1973/1977/1975/55571/9775/54464/57472/85456/29883/1974/167227 27 Norwalk_virus R-HSA-177929 Signaling by EGFR 25/1313 49/10654 4.927062892526793e-11 3.618038490902811e-10 1.7615285582749172e-10 5295/1839/4893/6464/685/5290/5335/5782/2069/7316/1950/6714/867/1445/998/6654/6233/2885/7311/1956/3845/2549/3265/5829/7314 25 Norwalk_virus R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 21/1313 36/10654 6.141673329391263e-11 4.4834215304556216e-10 2.1828609851830252e-10 26999/25/71/5747/10006/10458/5594/10152/8936/10163/10810/55845/998/695/8976/2885/23191/3071/10787/5879/5595 21 Norwalk_virus R-HSA-5654741 Signaling by FGFR3 22/1313 40/10654 1.0472283060500939e-10 7.600060396538986e-10 3.700271146031111e-10 5295/4893/6464/5290/5335/5594/7316/673/6714/8569/2261/867/6654/6233/2885/7311/5518/3845/2549/3265/7314/5595 22 Norwalk_virus R-HSA-109581 Apoptosis 54/1313 178/10654 1.0936213078752278e-10 7.890604901588127e-10 3.8417296861712413e-10 4000/596/5684/1612/1499/7531/5747/1029/842/5707/8737/7532/207/5594/2810/841/7534/7316/8655/7082/6774/660/5688/10134/329/999/5588/836/10000/5686/8837/4137/5710/7157/208/5704/6233/5580/6709/5716/6093/1613/7311/839/840/1630/5599/317/5062/5693/140735/7529/7314/5595 54 Norwalk_virus R-HSA-194315 Signaling by Rho GTPases 104/1313 455/10654 1.184091934848524e-10 8.451474287400703e-10 4.1148023588515245e-10 26999/5170/25/5590/5903/1072/3984/79861/54908/71/5579/1499/25936/7531/5747/80776/1783/10006/4627/2316/7532/10928/10458/5578/10382/9212/5594/3985/613/1027/1080/2810/7277/348995/79023/57122/79980/6232/7534/332/1780/5528/5048/1781/8655/5289/5585/4168/10152/6714/23279/79902/8936/1432/10163/7846/999/23365/10810/347733/22919/55845/5063/9475/995/79003/11243/23221/51143/998/695/6654/90627/8976/2885/5580/23191/7514/6093/367/5518/10383/54820/5347/387/84790/5600/23332/25909/5058/801/3071/9793/10726/5586/5062/55746/140735/9886/7529/10787/5879/5595/1778 104 Norwalk_virus R-HSA-6785631 ERBB2 Regulates Cell Motility 13/1313 15/10654 1.184977055606545e-10 8.451474287400703e-10 4.1148023588515245e-10 1839/685/2065/2069/2064/1950/145957/3084/2066/9542/10718/387/1956 13 Norwalk_virus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 17/1313 25/10654 1.297175156226041e-10 9.198824965008668e-10 4.4786679078120157e-10 1147/5170/842/207/84335/1027/7249/6199/1026/64223/2932/10000/208/2475/2931/253260/4193 17 Norwalk_virus R-HSA-5663220 RHO GTPases Activate Formins 46/1313 140/10654 1.389361992994962e-10 9.796580871061066e-10 4.76969966494682e-10 5903/79861/54908/71/25936/80776/1783/10382/9212/7277/348995/79023/57122/79980/6232/332/1780/5528/5048/1781/8655/6714/23279/79902/7846/347733/22919/79003/11243/51143/998/7514/5518/10383/54820/5347/387/84790/23332/25909/9793/10726/55746/140735/5879/1778 46 Norwalk_virus R-HSA-5633007 Regulation of TP53 Activity 50/1313 160/10654 1.6773073840918363e-10 1.17601043144518e-9 5.725688007545133e-10 1017/5170/5563/5883/1029/1459/6446/8445/207/22974/9212/1460/545/639/7316/1457/983/6790/641/64223/4194/112858/3364/1432/10524/56950/10000/6794/2033/1111/3066/7157/1107/5371/208/6233/2475/672/7311/5562/5518/10419/8851/5600/1020/133746/5810/7314/253260/4193 50 Norwalk_virus R-HSA-2467813 Separation of Sister Chromatids 56/1313 190/10654 1.7047896353099507e-10 1.1885640097863196e-9 5.786808105664765e-10 5684/5903/79861/54908/25936/80776/55869/1783/5707/10382/9212/7277/348995/79023/57122/79980/6232/332/1780/5885/5528/5048/1781/7316/8655/23279/79902/5688/7846/347733/22919/5686/79003/11243/5710/51143/5704/6233/5716/7514/7311/5518/10383/54820/5347/84790/29882/23332/25909/9793/10726/55746/5693/140735/7314/1778 56 Norwalk_virus R-HSA-68882 Mitotic Anaphase 58/1313 201/10654 2.0209968655408287e-10 1.4011492235397589e-9 6.821830054809973e-10 4000/5684/5903/79861/54908/25936/80776/55869/1783/5707/10382/9212/7277/348995/79023/57122/79980/6232/332/1780/5885/5528/5048/1781/7316/8655/23279/79902/5688/7846/347733/22919/5686/79003/11243/5710/51143/5704/6233/5716/7514/7311/5518/10383/54820/5347/84790/29882/23332/25909/9793/10726/55746/7112/5693/140735/7314/1778 58 Norwalk_virus R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 31/1313 75/10654 2.2880001917628684e-10 1.5774490210987332e-9 7.680187778198166e-10 23165/5903/55706/7175/9631/6428/348995/79023/57122/23636/10762/23511/4686/53371/11338/23279/4927/9688/79902/9883/23225/10189/10482/8086/9972/8021/9775/129401/55746/22916/8480 31 Norwalk_virus R-HSA-6802952 Signaling by BRAF and RAF fusions 29/1313 67/10654 2.305837710565049e-10 1.5809638667465336e-9 7.697300644747533e-10 4000/27044/818/815/4893/71/5604/10142/283455/8844/817/5594/5908/23164/673/6714/3717/2335/3690/408/1445/816/5894/3845/3265/369/801/7529/5595 29 Norwalk_virus R-HSA-2555396 Mitotic Metaphase and Anaphase 58/1313 202/10654 2.5031519340224845e-10 1.7068195330340128e-9 8.310059052220394e-10 4000/5684/5903/79861/54908/25936/80776/55869/1783/5707/10382/9212/7277/348995/79023/57122/79980/6232/332/1780/5885/5528/5048/1781/7316/8655/23279/79902/5688/7846/347733/22919/5686/79003/11243/5710/51143/5704/6233/5716/7514/7311/5518/10383/54820/5347/84790/29882/23332/25909/9793/10726/55746/7112/5693/140735/7314/1778 58 Norwalk_virus R-HSA-202403 TCR signaling 41/1313 119/10654 2.7074757659036156e-10 1.8360532379707033e-9 8.939264248655022e-10 5295/8454/1147/5170/8945/5684/5290/5335/6885/5707/6500/3123/23118/8517/3126/7316/3122/920/5688/23291/5588/5686/5063/5728/1445/5710/5704/6233/5716/3702/7311/3932/3127/3125/7334/3551/5058/5062/5693/997/7314 41 Norwalk_virus R-HSA-72202 Transport of Mature Transcript to Cytoplasm 33/1313 84/10654 3.012594069676733e-10 2.031863717646101e-9 9.892614393560899e-10 23165/5903/55706/7175/9631/7884/6428/348995/79023/57122/23636/10762/23511/4686/53371/11338/23279/4927/9688/79902/9883/23225/10189/10482/8086/1977/9972/8021/9775/129401/55746/22916/8480 33 Norwalk_virus R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 14/1313 18/10654 3.3094870692466255e-10 2.220039704289223e-9 1.0808794183485426e-9 1839/4893/5578/5594/5598/6195/6654/2885/6196/1956/6197/3845/3265/5595 14 Norwalk_virus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 31/1313 77/10654 5.048146324840717e-10 3.3681449403910372e-9 1.6398619074468431e-9 23165/5893/5903/55706/7175/9631/1029/348995/79023/57122/23636/10762/5885/23511/53371/641/23279/4927/9688/79902/9883/23225/1069/8086/5371/672/9972/8021/129401/55746/8480 31 Norwalk_virus R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 15/1313 21/10654 5.611307473536064e-10 3.7238676869830243e-9 1.8130540331042505e-9 4849/4869/4850/9337/25904/246175/4848/23019/995/7157/55571/55835/57472/85456/29883 15 Norwalk_virus R-HSA-1250342 PI3K events in ERBB4 signaling 10/1313 10/10654 7.84214351304338e-10 5.176648989195125e-9 2.5203753507765403e-9 5295/1839/685/5290/2069/145957/3084/2066/9542/10718 10 Norwalk_virus R-HSA-198323 AKT phosphorylates targets in the cytosol 12/1313 14/10654 8.411941997166334e-10 5.4655602191012675e-9 2.661038691856421e-9 1147/842/207/84335/1027/7249/1026/2932/10000/208/2931/4193 12 Norwalk_virus R-HSA-3371568 Attenuation phase 12/1313 14/10654 8.411941997166334e-10 5.4655602191012675e-9 2.661038691856421e-9 3303/3337/3305/3320/2033/3326/3306/3304/3312/3297/2288/10728 12 Norwalk_virus R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 12/1313 14/10654 8.411941997166334e-10 5.4655602191012675e-9 2.661038691856421e-9 4893/1793/5753/1398/9844/387/9564/3845/3265/63916/5829/5879 12 Norwalk_virus R-HSA-5674135 MAP2K and MAPK activation 21/1313 40/10654 8.859663775140605e-10 5.7264805963278595e-9 2.7880740169576247e-9 4893/71/5604/283455/8844/5594/5908/673/6714/8649/2335/3690/408/1445/5894/3845/3265/369/7529/28956/5595 21 Norwalk_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 20/1313 37/10654 1.1331149313568887e-9 7.285987719243e-9 3.54735735259806e-9 1017/5170/1029/6446/207/639/7316/983/64223/4194/10000/7157/208/6233/2475/7311/5518/7314/253260/4193 20 Norwalk_virus R-HSA-9639288 Amino acids regulate mTORC1 25/1313 55/10654 1.1470895578778284e-9 7.337825470754562e-9 3.572595801529428e-9 526/389541/9550/9114/58528/153129/10312/527/64223/10325/529/8649/6009/57600/10542/2475/55004/10670/523/201163/96459/64121/57521/10641/28956 25 Norwalk_virus R-HSA-69231 Cyclin D associated events in G1 22/1313 44/10654 1.188275505444355e-9 7.52372399110431e-9 3.6631049415953807e-9 8454/25/1019/1029/1027/6500/5925/7316/5753/1026/6714/4067/3717/6502/1021/595/6233/7311/5518/1163/1022/7314 22 Norwalk_virus R-HSA-69236 G1 Phase 22/1313 44/10654 1.188275505444355e-9 7.52372399110431e-9 3.6631049415953807e-9 8454/25/1019/1029/1027/6500/5925/7316/5753/1026/6714/4067/3717/6502/1021/595/6233/7311/5518/1163/1022/7314 22 Norwalk_virus R-HSA-5654743 Signaling by FGFR4 21/1313 41/10654 1.6064195489386497e-9 1.0119627716918093e-8 4.926982746945151e-9 5295/4893/6464/5290/5335/5594/7316/673/6714/8569/867/6654/6233/2885/7311/5518/3845/2549/3265/7314/5595 21 Norwalk_virus R-HSA-9006115 Signaling by NTRK2 (TRKB) 16/1313 25/10654 1.785247148814149e-9 1.1189352079183631e-8 5.447803633276564e-9 5295/4893/6464/5290/5335/4915/6714/2534/6654/2885/8851/3845/2549/3265/1020/5879 16 Norwalk_virus R-HSA-202424 Downstream TCR signaling 35/1313 98/10654 1.8342576898584813e-9 1.1438762779469223e-8 5.569235196925514e-9 5295/8454/1147/5170/8945/5684/5290/6885/5707/6500/3123/23118/8517/3126/7316/3122/920/5688/23291/5588/5686/5728/5710/5704/6233/5716/7311/3932/3127/3125/7334/3551/5693/997/7314 35 Norwalk_virus R-HSA-8939211 ESR-mediated signaling 60/1313 223/10654 2.0340319010444152e-9 1.2621167945980596e-8 6.14491742736576e-9 5295/5170/27161/3725/596/5434/5590/1839/4893/6464/685/857/5290/7090/5241/5747/8204/207/2625/5594/2069/1027/3315/5481/192670/5885/2100/4313/1950/6667/2289/6714/2099/4609/10524/10000/3320/2033/4846/595/192669/2066/2771/208/3326/7514/1025/1386/1956/5536/3169/3845/858/3265/26523/801/3480/2288/10728/5595 60 Norwalk_virus R-HSA-211000 Gene Silencing by RNA 43/1313 136/10654 2.1383341097677197e-9 1.3202351394138012e-8 6.42788048707343e-9 11022/23165/27161/5434/8468/5903/55706/7175/9631/91646/122402/348995/79023/57122/23636/192670/10762/23511/56165/53371/55124/23279/4927/9688/79902/9883/23225/84944/3320/54514/192669/8086/9972/54456/8021/129401/26523/143689/9271/55746/23405/136991/8480 43 Norwalk_virus R-HSA-373755 Semaphorin interactions 27/1313 65/10654 2.916235594335747e-9 1.791608105233001e-8 8.722872491655649e-9 1072/3984/5361/4627/3985/10371/2064/8829/4233/2932/55558/23365/3320/5063/2534/9475/91584/3326/6093/5362/387/8851/5058/1020/5062/5879/2242 27 Norwalk_virus R-HSA-5218920 VEGFR2 mediated vascular permeability 17/1313 29/10654 3.8232632712172275e-9 2.3372757239313197e-8 1.13795857800295e-8 5170/857/1499/207/64223/10000/3320/5063/4846/3728/208/2475/5058/801/5062/5879/253260 17 Norwalk_virus R-HSA-141424 Amplification of signal from the kinetochores 34/1313 96/10654 4.011508149605817e-9 2.428430055444302e-8 1.1823392440943462e-8 5903/54908/25936/80776/1783/9212/348995/79023/57122/79980/6232/332/1780/5528/5048/1781/8655/23279/79902/22919/79003/11243/51143/7514/5518/54820/5347/23332/25909/9793/10726/55746/140735/1778 34 Norwalk_virus R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 34/1313 96/10654 4.011508149605817e-9 2.428430055444302e-8 1.1823392440943462e-8 5903/54908/25936/80776/1783/9212/348995/79023/57122/79980/6232/332/1780/5528/5048/1781/8655/23279/79902/22919/79003/11243/51143/7514/5518/54820/5347/23332/25909/9793/10726/55746/140735/1778 34 Norwalk_virus R-HSA-199418 Negative regulation of the PI3K/AKT network 37/1313 110/10654 4.281633665221959e-9 2.579372513854588e-8 1.2558291894927976e-8 5295/1839/685/5290/3667/2065/207/5594/2069/2064/2260/5528/2100/1950/4233/6714/2099/2261/5159/10000/145957/3084/2534/5728/3630/2066/3654/208/9542/2885/10718/3932/5518/1956/2549/5879/5595 37 Norwalk_virus R-HSA-6807878 COPI-mediated anterograde transport 35/1313 101/10654 4.603555439155851e-9 2.7599093236678314e-8 1.3437278525682475e-8 79861/11258/1783/10382/93661/5861/55860/830/7277/10671/1780/1781/9570/8655/84516/1639/832/10282/10121/81876/9527/7846/347733/51143/3630/10540/4905/6709/10383/84790/378/140735/829/51164/1778 35 Norwalk_virus R-HSA-1433557 Signaling by SCF-KIT 21/1313 43/10654 4.913068157116948e-9 2.9313065302798714e-8 1.4271766812677774e-8 5295/4893/5290/5578/2241/9306/6774/6714/867/4067/3717/2534/1111/6654/2885/7525/3932/3845/3265/5879/2242 21 Norwalk_virus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 19/1313 36/10654 5.057269999655552e-9 2.988605747415496e-8 1.4550741753394923e-8 4893/71/5604/283455/8844/5594/5908/673/6714/2335/3690/408/1445/5894/3845/3265/369/7529/5595 19 Norwalk_virus R-HSA-6804757 Regulation of TP53 Degradation 19/1313 36/10654 5.057269999655552e-9 2.988605747415496e-8 1.4550741753394923e-8 1017/5170/1029/6446/207/7316/983/64223/4194/10000/7157/208/6233/2475/7311/5518/7314/253260/4193 19 Norwalk_virus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 11/1313 13/10654 5.903400057399064e-9 3.472094536129023e-8 1.6904722539022514e-8 2065/207/2064/7316/10000/3084/208/9542/6233/7311/7314 11 Norwalk_virus R-HSA-8878166 Transcriptional regulation by RUNX2 39/1313 121/10654 6.506441380550594e-9 3.808723468520418e-8 1.854368099521371e-8 8454/25/1019/5684/5707/10273/207/5594/3280/6500/5925/10013/7316/11059/9759/983/1026/6714/2099/2932/5688/6502/2908/10000/5686/595/55294/5710/208/5704/6233/7525/5716/7311/367/1750/5693/7314/5595 39 Norwalk_virus R-HSA-5675221 Negative regulation of MAPK pathway 20/1313 40/10654 6.8000344065167935e-9 3.961897980510489e-8 1.928944773580746e-8 4893/5604/8844/5594/5528/7316/673/1852/5894/6233/7311/5518/5536/1843/3845/3265/369/7529/7314/5595 20 Norwalk_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 31/1313 85/10654 8.667079223150581e-9 5.026095942023304e-8 2.4470749995516156e-8 8454/1017/1019/5684/5707/207/1027/6500/5925/4149/7316/5753/1026/4609/5688/6502/10000/5686/595/5710/208/5704/6233/5716/51343/7311/7465/1163/1022/5693/7314 31 Norwalk_virus R-HSA-5218921 VEGFR2 mediated cell proliferation 14/1313 21/10654 8.756795560963482e-9 5.05450385635148e-8 2.4609060719672165e-8 5170/5590/4893/5335/5579/7422/5578/6714/5580/3791/3710/3845/3265/801 14 Norwalk_virus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 15/1313 24/10654 9.402826211713838e-9 5.377376649187499e-8 2.618104412090101e-8 6885/5606/10392/23118/8517/7316/1432/3656/10454/3654/6233/7311/5600/7334/7314 15 Norwalk_virus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 15/1313 24/10654 9.402826211713838e-9 5.377376649187499e-8 2.618104412090101e-8 596/1839/685/5747/207/5594/2069/1027/1950/10000/595/208/7514/1956/5595 15 Norwalk_virus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 29/1313 77/10654 1.1220895822170751e-8 6.387675098767846e-8 3.109992371765337e-8 5684/79861/51512/5707/63943/10382/7277/9133/7316/983/1026/5688/7846/347733/3320/22919/5686/5710/7157/5704/6233/3326/5716/7311/10383/5347/84790/5693/7314 29 Norwalk_virus R-HSA-1295596 Spry regulation of FGF signaling 12/1313 16/10654 1.324679340469171e-8 7.506516262658636e-8 3.654726947509273e-8 5594/7316/673/6714/8569/867/6233/2885/7311/5518/7314/5595 12 Norwalk_virus R-HSA-453279 Mitotic G1-G1/S phases 44/1313 149/10654 1.4556770826569007e-8 8.211342088987335e-8 3.997888255717996e-8 8454/1017/4172/25/1019/5684/1029/5707/207/1027/6500/5925/4149/7316/4174/5753/983/1026/6714/4171/4609/5688/4067/3717/6502/10000/5686/1021/595/5710/208/5704/6233/5716/23595/7311/5518/7465/1163/1022/1859/5693/7314/6241 44 Norwalk_virus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 22/1313 49/10654 1.5185441166886297e-8 8.527209270636151e-8 4.151675746507614e-8 1017/4849/1027/4869/4850/2810/9337/983/1026/6790/25904/246175/4848/23019/2033/995/7157/55571/55835/57472/85456/29883 22 Norwalk_virus R-HSA-8943724 Regulation of PTEN gene transcription 25/1313 61/10654 1.5605751997586546e-8 8.723755959011218e-8 4.2473692018087616e-8 3725/5468/389541/2146/5594/58528/153129/64223/10014/10325/8649/6009/6615/3066/7157/1107/10542/2475/55004/1386/10670/64121/57521/28956/5595 25 Norwalk_virus R-HSA-6784531 tRNA processing in the nucleus 24/1313 57/10654 1.6012805756001512e-8 8.911162306366761e-8 4.338612463509497e-8 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 24 Norwalk_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 34/1313 101/10654 1.7698173407321633e-8 9.805104106467029e-8 4.773849405922283e-8 8454/1147/5170/8945/5684/4773/6885/4772/5707/6500/23118/841/8517/7316/9020/6714/5688/23291/5686/5710/10454/9040/5704/6233/5580/5716/7311/3710/7334/3551/801/5693/997/7314 34 Norwalk_virus R-HSA-69202 Cyclin E associated events during G1/S transition 30/1313 83/10654 1.912872738366907e-8 1.0550555859170363e-7 5.136790417883531e-8 8454/1017/1019/5684/5707/207/1027/6500/5925/4149/7316/5753/1026/4609/5688/6502/10000/5686/595/5710/208/5704/6233/5716/7311/7465/1163/1022/5693/7314 30 Norwalk_virus R-HSA-1489509 DAG and IP3 signaling 20/1313 42/10654 1.984138110096238e-8 1.0895200861192175e-7 5.3045890786923183e-8 818/815/5335/5575/5567/817/5578/5582/5573/10645/5566/84254/816/5613/5577/5580/3710/5581/801/814 20 Norwalk_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 31/1313 88/10654 2.2420880503230788e-8 1.225740647775745e-7 5.967811457850441e-8 3303/5684/5073/5707/207/5578/3315/26986/7534/7316/1432/5688/5686/1981/5710/5704/6233/5580/5716/7514/7311/8021/54464/5600/3304/3312/5693/167227/7529/7314/1994 31 Norwalk_virus R-HSA-5654736 Signaling by FGFR1 22/1313 50/10654 2.3984125730642443e-8 1.305451755777512e-7 6.35590404865594e-8 5295/4893/6464/5290/5335/5594/2260/7316/673/6714/8569/867/6654/6233/2885/7311/5518/3845/2549/3265/7314/5595 22 Norwalk_virus R-HSA-180336 SHC1 events in EGFR signaling 11/1313 14/10654 2.446482153556812e-8 1.3258010273205255e-7 6.454979343330776e-8 1839/4893/6464/685/2069/1950/6654/2885/1956/3845/3265 11 Norwalk_virus R-HSA-4551638 SUMOylation of chromatin organization proteins 27/1313 71/10654 2.82055573175374e-8 1.5218737665679962e-7 7.409606361678018e-8 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/9759/23279/4927/9688/79902/9883/23225/3066/1107/8086/9972/8021/129401/55746/8480 27 Norwalk_virus R-HSA-5687128 MAPK6/MAPK4 signaling 31/1313 89/10654 3.039927381459222e-8 1.6331384763596944e-7 7.951325208282497e-8 27161/3725/5684/5707/5567/3315/3337/192670/5596/7316/983/4609/5566/5688/5686/5063/5710/192669/998/5704/6233/5716/7514/7311/5896/26523/5058/5062/5693/7314/5879 31 Norwalk_virus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 34/1313 103/10654 3.0926607795531445e-8 1.65430690837304e-7 8.054388781594852e-8 5295/1839/685/5290/3667/2065/207/5594/2069/2064/2260/5528/2100/1950/4233/6714/2099/2261/5159/145957/3084/2534/3630/2066/3654/9542/2885/10718/3932/5518/1956/2549/5879/5595 34 Norwalk_virus R-HSA-180292 GAB1 signalosome 12/1313 17/10654 3.9970556852892945e-8 2.1198060279675274e-7 1.0320782561205826e-7 5295/1839/685/5290/2069/1950/6714/1445/2885/1956/2549/5829 12 Norwalk_virus R-HSA-9034015 Signaling by NTRK3 (TRKC) 12/1313 17/10654 3.9970556852892945e-8 2.1198060279675274e-7 1.0320782561205826e-7 5295/4893/6464/5290/3667/5335/6714/6654/2885/3845/3265/4916 12 Norwalk_virus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 14/1313 23/10654 4.8363019359627595e-8 2.5539790223530997e-7 1.2434657609149493e-7 6885/10392/23118/8517/7316/3656/10454/3654/5609/6233/7311/5599/7334/7314 14 Norwalk_virus R-HSA-2559585 Oncogene Induced Senescence 17/1313 33/10654 5.284405136537187e-8 2.7787910061197666e-7 1.3529208511919472e-7 1019/1029/5594/5925/192670/7316/6667/4194/1021/192669/7157/6233/7311/26523/7314/5595/4193 17 Norwalk_virus R-HSA-8853334 Signaling by FGFR3 fusions in cancer 9/1313 10/10654 5.6960182568588164e-8 2.9825985893509667e-7 1.4521494467852369e-7 5295/4893/5290/2261/6654/2885/3845/2549/3265 9 Norwalk_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 16/1313 30/10654 6.928151517150675e-8 3.6125361482285663e-7 1.758849611165187e-7 1147/6885/8737/55072/23118/8517/7316/7128/329/10616/10454/6233/7311/1540/3551/7314 16 Norwalk_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 31/1313 92/10654 7.317951522051972e-8 3.799823363542467e-7 1.8500348705826173e-7 1017/5563/5883/1459/8445/22974/9212/1460/545/7316/1457/6790/641/4194/112858/3364/1432/10524/6794/1111/7157/6233/672/7311/5562/8851/5600/1020/5810/7314/4193 31 Norwalk_virus R-HSA-162906 HIV Infection 58/1313 233/10654 7.877574610194172e-8 4.0733625380212364e-7 1.9832139588822172e-7 23165/8945/5434/5684/5903/8065/55706/7175/9631/3159/5707/4869/6500/348995/79023/57122/23636/10762/23511/4686/7316/53371/920/292/3055/23279/4927/9688/8731/79902/9883/5688/23225/5686/2534/5710/8086/5704/6233/5716/7514/163/1025/9844/7311/9972/3932/8021/129401/6829/1022/5062/55746/22916/5693/8480/7314/5879 58 Norwalk_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 22/1313 53/10654 8.650283143026195e-8 4.4543574192927424e-7 2.1687104276466638e-7 596/7531/1029/842/7532/207/5594/2810/841/7534/8655/6774/836/10000/7157/208/840/5599/317/140735/7529/5595 22 Norwalk_virus R-HSA-69618 Mitotic Spindle Checkpoint 35/1313 112/10654 9.240677308735784e-8 4.7192100988235016e-7 2.297660288158692e-7 5903/54908/25936/80776/1783/9212/348995/79023/57122/79980/6232/332/1780/5528/5048/1781/8655/23279/79902/22919/79003/11243/51143/7514/5518/54820/5347/29882/23332/25909/9793/10726/55746/140735/1778 35 Norwalk_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 35/1313 112/10654 9.240677308735784e-8 4.7192100988235016e-7 2.297660288158692e-7 5295/8454/1147/8945/5684/4893/4773/6885/5579/4772/5707/640/6500/8517/7316/5688/4067/23291/5686/2534/5710/695/6654/5704/6233/2885/5716/7311/3710/3845/3265/3551/801/5693/7314 35 Norwalk_virus R-HSA-187687 Signalling to ERKs 17/1313 34/10654 9.359573440974447e-8 4.760340426331676e-7 2.317685571664941e-7 4893/6464/5604/5594/673/57498/6714/1432/4914/6654/2885/1398/3845/5600/3265/7529/5595 17 Norwalk_virus R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 27/1313 75/10654 1.0756332246793235e-7 5.448411558477716e-7 2.6526894563520163e-7 5295/1839/685/5290/3667/2065/2069/2064/2260/2100/1950/4233/6714/2099/2261/5159/145957/3084/2534/2066/9542/2885/10718/3932/1956/2549/5879 27 Norwalk_virus R-HSA-445144 Signal transduction by L1 13/1313 21/10654 1.1173532394397122e-7 5.613908381152562e-7 2.7332655420344976e-7 5604/1459/5594/1460/2260/8829/1457/3690/3685/1956/5058/5879/5595 13 Norwalk_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 13/1313 21/10654 1.1173532394397122e-7 5.613908381152562e-7 2.7332655420344976e-7 9252/4893/5567/5566/4067/5063/2534/2033/5894/3845/3265/5058/5062 13 Norwalk_virus R-HSA-111996 Ca-dependent events 18/1313 38/10654 1.1315996323752573e-7 5.662561063619735e-7 2.756953263936323e-7 818/815/5575/5567/817/5578/5594/5582/5573/10645/5566/84254/816/5613/5577/5580/801/814 18 Norwalk_virus R-HSA-3928662 EPHB-mediated forward signaling 19/1313 42/10654 1.2629878111446098e-7 6.294650094901448e-7 3.0647009241048665e-7 1072/3984/71/5747/3985/2051/6714/4067/2047/2534/9475/998/8976/7525/6093/387/3265/5058/5879 19 Norwalk_virus R-HSA-179812 GRB2 events in EGFR signaling 10/1313 13/10654 1.5748596793859255e-7 7.817603448471735e-7 3.806187183021143e-7 1839/4893/685/2069/1950/6654/2885/1956/3845/3265 10 Norwalk_virus R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 14/1313 25/10654 2.0737031971661714e-7 1.0252851265670195e-6 4.991845817460192e-7 10694/79861/10575/10382/7277/10576/908/6950/7846/347733/10574/10383/84790/22948 14 Norwalk_virus R-HSA-2871796 FCERI mediated MAPK activation 16/1313 32/10654 2.247559607937221e-7 1.1068339180357504e-6 5.388885609674039e-7 3725/4893/6464/5335/5594/4067/5609/6654/2885/3845/5599/3265/5058/5062/5879/5595 16 Norwalk_virus R-HSA-399956 CRMPs in Sema3A signaling 11/1313 16/10654 2.3159348738469737e-7 1.1359980942466775e-6 5.530878375652853e-7 5361/10371/8829/2932/55558/2534/91584/5362/8851/1020/2242 11 Norwalk_virus R-HSA-5654738 Signaling by FGFR2 26/1313 73/10654 2.3617588360666846e-7 1.153914454944392e-6 5.618108462089834e-7 5295/5434/4893/6464/5290/5335/5594/3178/4686/7316/673/6714/8569/867/6654/6233/2885/7311/5518/3845/2549/3265/22916/5725/7314/5595 26 Norwalk_virus R-HSA-389357 CD28 dependent PI3K/Akt signaling 13/1313 22/10654 2.4229617611469783e-7 1.1745685724935158e-6 5.718667972443939e-7 5295/5170/1326/5290/207/9020/64223/10000/2534/208/2475/3932/253260 13 Norwalk_virus R-HSA-912631 Regulation of signaling by CBL 13/1313 22/10654 2.4229617611469783e-7 1.1745685724935158e-6 5.718667972443939e-7 5295/5290/7316/3055/867/4067/2534/6233/2885/7525/1398/7311/7314 13 Norwalk_virus R-HSA-111933 Calmodulin induced events 17/1313 36/10654 2.7047653450580016e-7 1.3010130981461161e-6 6.334293382551175e-7 818/815/5575/5567/817/5578/5582/5573/10645/5566/84254/816/5613/5577/5580/801/814 17 Norwalk_virus R-HSA-111997 CaM pathway 17/1313 36/10654 2.7047653450580016e-7 1.3010130981461161e-6 6.334293382551175e-7 818/815/5575/5567/817/5578/5582/5573/10645/5566/84254/816/5613/5577/5580/801/814 17 Norwalk_virus R-HSA-5655291 Signaling by FGFR4 in disease 9/1313 11/10654 2.787824245990687e-7 1.3357876020364642e-6 6.503601370447691e-7 5295/4893/5290/5335/6654/2885/3845/2549/3265 9 Norwalk_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 20/1313 48/10654 3.1034283975166915e-7 1.4812902466608516e-6 7.212015790180491e-7 5295/6464/5290/7534/7316/3055/5566/867/3558/4067/3717/2534/6654/6233/2885/7525/1398/3716/7311/7314 20 Norwalk_virus R-HSA-9614085 FOXO-mediated transcription 24/1313 65/10654 3.162736594049554e-7 1.503814602764558e-6 7.321681004171986e-7 857/65018/7532/207/1027/2810/4287/6720/7534/847/1026/2908/10000/6794/2033/3630/3066/6648/91584/208/604/23411/25942/7529 24 Norwalk_virus R-HSA-9020702 Interleukin-1 signaling 32/1313 103/10654 3.785910233238109e-7 1.7932498471177455e-6 8.730865704615005e-7 8454/1147/8945/1326/5684/351/6885/5604/4215/11213/5707/10392/6500/23118/8517/7316/79155/5688/23291/5686/3656/5710/10454/3654/5704/6233/5716/7311/7334/3551/5693/7314 32 Norwalk_virus R-HSA-8986944 Transcriptional Regulation by MECP2 23/1313 62/10654 5.042697677445726e-7 2.3794630485589905e-6 1.1584984858330388e-6 818/27161/815/5468/4986/6446/817/9212/192670/4233/2289/5566/4988/3064/5728/816/192669/3066/3654/25942/26523/801/814 23 Norwalk_virus R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 15/1313 30/10654 5.4042897474104e-7 2.5404255971728437e-6 1.2368669517597966e-6 818/5170/815/4893/817/5594/27330/6195/816/6196/6197/3845/3265/801/5595 15 Norwalk_virus R-HSA-390466 Chaperonin-mediated protein folding 30/1313 95/10654 5.890221143650982e-7 2.758401675196554e-6 1.3429938178572647e-6 10694/26224/6000/79861/2629/1459/10575/10382/1460/7277/10576/908/8786/6774/1457/26272/26270/6950/7846/347733/55294/26190/7157/2771/10574/10383/54461/84790/22948/9628 30 Norwalk_virus R-HSA-611105 Respiratory electron transport 31/1313 100/10654 6.056977288075085e-7 2.8258303813914212e-6 1.3758230959062522e-6 4723/1329/4700/1345/4719/4704/4710/4724/4729/7386/4714/84987/4718/4701/7385/4728/4725/4695/10128/4731/55967/4705/7381/4726/7384/54539/4698/1340/1327/4720/51079 31 Norwalk_virus R-HSA-69206 G1/S Transition 37/1313 131/10654 6.935419407106454e-7 3.223541379857344e-6 1.5694582060631204e-6 8454/1017/4172/1019/5684/5707/207/1027/6500/5925/4149/7316/4174/5753/983/1026/4171/4609/5688/6502/10000/5686/595/5710/208/5704/6233/5716/23595/7311/5518/7465/1163/1022/5693/7314/6241 37 Norwalk_virus R-HSA-111465 Apoptotic cleavage of cellular proteins 17/1313 38/10654 7.103779711772097e-7 3.277245584501551e-6 1.595605382335036e-6 4000/1499/5747/841/7082/660/10134/329/999/5588/836/4137/5580/6709/6093/839/840 17 Norwalk_virus R-HSA-5689896 Ovarian tumor domain proteases 17/1313 38/10654 7.103779711772097e-7 3.277245584501551e-6 1.595605382335036e-6 8737/10392/7706/8517/7316/79155/983/2099/7415/23586/7128/5728/7157/6233/7311/387/7314 17 Norwalk_virus R-HSA-68875 Mitotic Prophase 39/1313 142/10654 7.670651094231082e-7 3.5256585214595456e-6 1.7165511610482034e-6 4000/23165/4926/5903/55706/7175/5579/9631/91754/5578/5594/5861/5925/348995/79023/9133/57122/23636/10762/23511/53371/983/23279/4927/9688/79902/81876/9883/23225/8086/9972/5518/5347/8021/129401/55746/7112/8480/5595 39 Norwalk_virus R-HSA-2871837 FCERI mediated NF-kB activation 27/1313 82/10654 8.504637796402763e-7 3.894559227061192e-6 1.8961592911770002e-6 8454/1147/5170/8945/5684/6885/5707/6500/23118/8517/7316/5688/4067/23291/5588/5686/5710/10454/5704/6233/5716/7311/7334/3551/5693/997/7314 27 Norwalk_virus R-HSA-6799198 Complex I biogenesis 21/1313 55/10654 9.042286739680534e-7 4.112293760558053e-6 2.002168555545462e-6 4723/4700/4719/4704/4710/4724/4729/4714/4718/4701/4728/4725/4695/4731/55967/4705/4726/54539/4698/4720/51079 21 Norwalk_virus R-HSA-190236 Signaling by FGFR 28/1313 87/10654 9.04638353450724e-7 4.112293760558053e-6 2.002168555545462e-6 5295/5434/4893/6464/5290/5335/5594/3178/2260/4686/7316/673/6714/8569/2261/867/6654/6233/2885/7311/5518/3845/2549/3265/22916/5725/7314/5595 28 Norwalk_virus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 15/1313 31/10654 9.281643975995541e-7 4.203839479638857e-6 2.046739778033593e-6 3725/9252/5594/5528/5598/1432/6195/6196/5518/1386/6197/5599/5600/51231/5595 15 Norwalk_virus R-HSA-2682334 EPH-Ephrin signaling 29/1313 92/10654 9.439805462648136e-7 4.259926756053213e-6 2.074047209783744e-6 1072/3984/71/5747/4627/3985/23385/4313/2051/2041/6714/4067/2043/2047/5063/2534/9475/998/8976/7525/6093/163/387/3265/5058/5062/5663/1969/5879 29 Norwalk_virus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 57/1313 244/10654 9.805799981104705e-7 4.409057165417007e-6 2.1466549157719686e-6 10450/23165/6635/5434/5903/55706/7175/9631/7884/27339/9879/6428/8106/9589/3178/23450/348995/79023/57122/23636/3183/10762/5093/23511/10594/4686/53371/11338/9343/3190/56339/23279/4927/9688/79902/22938/988/9883/23020/23225/10189/10482/8086/2521/1977/57721/9972/8021/9775/129401/3312/55746/22916/5725/8480/10262/1994 57 Norwalk_virus R-HSA-74752 Signaling by Insulin receptor 26/1313 78/10654 1.0367650109482228e-6 4.644856962407019e-6 2.2614596856708336e-6 5295/5170/4893/6464/5290/3667/526/9550/9114/5594/2322/2260/10312/527/5289/2261/529/3630/208/6654/2885/3845/2549/3265/523/5595 26 Norwalk_virus R-HSA-9020591 Interleukin-12 signaling 19/1313 47/10654 1.0716962634998879e-6 4.784082960443744e-6 2.32924519215803e-6 1072/9049/5908/3313/6175/6647/6950/3717/5306/3458/998/6648/3716/6845/4282/7297/5062/5034/829 19 Norwalk_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 27/1313 83/10654 1.114467422375496e-6 4.946510926537129e-6 2.408327131627561e-6 8454/1147/8945/5684/4893/4773/6885/5579/4772/5707/6500/8517/7316/5688/23291/5686/5710/5704/6233/5716/7311/3845/3265/3551/801/5693/7314 27 Norwalk_virus R-HSA-75893 TNF signaling 18/1313 43/10654 1.1160540366078939e-6 4.946510926537129e-6 2.408327131627561e-6 1147/6885/8737/55072/9530/23118/841/8517/7316/7128/329/10616/10454/6233/7311/1540/3551/7314 18 Norwalk_virus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 22/1313 60/10654 1.122774695597679e-6 4.958588602265906e-6 2.414207436872328e-6 8454/1017/1019/5684/5707/1027/6500/7316/5753/1026/5688/6502/5686/595/5710/5704/6233/5716/7311/1163/5693/7314 22 Norwalk_virus R-HSA-2132295 MHC class II antigen presentation 35/1313 123/10654 1.1389179011110315e-6 5.012046508080816e-6 2.4402346966693996e-6 114876/79861/11258/1783/10382/93661/821/55860/830/3123/7277/3126/10671/1780/1781/3122/8655/84516/1639/832/10121/7846/5476/347733/51143/10540/163/10383/84790/3127/3125/140735/829/51164/1778 35 Norwalk_virus R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 10/1313 15/10654 1.307156231291576e-6 5.732087925911116e-6 2.790804079454583e-6 29110/81844/23220/147945/7316/22954/3661/6233/7311/7314 10 Norwalk_virus R-HSA-446652 Interleukin-1 family signaling 38/1313 140/10654 1.456226483351639e-6 6.363299527603465e-6 3.0981245420453704e-6 8454/1147/834/8945/1326/5684/351/6885/5604/4215/11213/5782/5707/10392/29110/6500/23118/8517/7316/79155/6774/5688/23291/5686/84867/3656/5710/10454/3654/5704/6233/5716/7311/5599/7334/3551/5693/7314 38 Norwalk_virus R-HSA-1234174 Cellular response to hypoxia 25/1313 75/10654 1.6665022545083197e-6 7.2565940275257006e-6 3.533046330887445e-6 5684/64344/112399/5707/84962/7422/3091/7316/8994/5688/5686/2033/5710/7428/8453/5704/6233/5716/7311/2034/55662/54583/405/5693/7314 25 Norwalk_virus R-HSA-447115 Interleukin-12 family signaling 21/1313 57/10654 1.7940484982412145e-6 7.784664987123591e-6 3.790150305448868e-6 1072/9049/821/5908/3313/6175/6774/6647/6950/3717/5306/3458/998/6648/3716/6845/4282/7297/5062/5034/829 21 Norwalk_virus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 8/1313 10/10654 1.8662137796355878e-6 8.069586412988726e-6 3.928871115022291e-6 6885/23118/7316/3656/10454/6233/7311/7314 8 Norwalk_virus R-HSA-5688426 Deubiquitination 65/1313 297/10654 2.004920730714463e-6 8.639259120891141e-6 4.206229895577859e-6 23032/5684/6885/51651/7419/5707/8737/10392/4738/2625/9817/91833/1080/3091/4287/7706/8517/7416/7316/79155/7417/9738/983/8678/2099/4609/7415/4194/23586/7128/4798/5688/329/7046/6502/7347/5686/2033/408/5728/5710/10454/7157/10869/10868/63891/5704/6233/5716/672/7048/9804/7311/367/114548/387/23770/8607/7345/3054/1540/5693/154/7314/4193 65 Norwalk_virus R-HSA-186763 Downstream signal transduction 14/1313 29/10654 2.231699647545295e-6 9.517317053621e-6 4.63373339732682e-6 5295/4893/5290/5335/6778/6774/6714/5159/6654/2885/1398/9564/3845/3265 14 Norwalk_virus R-HSA-5205647 Mitophagy 14/1313 29/10654 2.231699647545295e-6 9.517317053621e-6 4.63373339732682e-6 65018/1459/10452/1460/7416/100188893/7316/1457/6714/8408/6233/9804/7311/7314 14 Norwalk_virus R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 14/1313 29/10654 2.231699647545295e-6 9.517317053621e-6 4.63373339732682e-6 11022/5434/8468/91646/122402/56165/55124/84944/3320/54514/54456/143689/9271/136991 14 Norwalk_virus R-HSA-198753 ERK/MAPK targets 12/1313 22/10654 2.3026086429908553e-6 9.752687119288914e-6 4.748328942255258e-6 9252/5594/5528/5598/1432/6195/6196/5518/6197/5600/51231/5595 12 Norwalk_virus R-HSA-9613829 Chaperone Mediated Autophagy 12/1313 22/10654 2.3026086429908553e-6 9.752687119288914e-6 4.748328942255258e-6 1915/1080/10013/5116/7316/3920/3320/6233/3326/7311/3312/7314 12 Norwalk_virus R-HSA-391251 Protein folding 30/1313 101/10654 2.4855131286556975e-6 1.0491570723339187e-5 5.108072093979128e-6 10694/26224/6000/79861/2629/1459/10575/10382/1460/7277/10576/908/8786/6774/1457/26272/26270/6950/7846/347733/55294/26190/7157/2771/10574/10383/54461/84790/22948/9628 30 Norwalk_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 15/1313 33/10654 2.517371813748478e-6 1.0554251421830613e-5 5.138589690937506e-6 1147/351/6885/10392/23118/8517/7316/3656/10454/3654/6233/7311/7334/3551/7314 15 Norwalk_virus R-HSA-9022692 Regulation of MECP2 expression and activity 15/1313 33/10654 2.517371813748478e-6 1.0554251421830613e-5 5.138589690937506e-6 818/27161/815/817/9212/192670/5566/3064/816/192669/3066/25942/26523/801/814 15 Norwalk_virus R-HSA-5619115 Disorders of transmembrane transporters 44/1313 176/10654 2.5526685931628235e-6 1.0636700715422485e-5 5.178732101151453e-6 23165/5684/5903/55706/7175/9631/6559/5707/1080/348995/79023/57122/23636/10762/23511/7316/53371/23279/4927/9688/7415/79902/9883/5688/23225/682/215/5686/5710/8086/10613/5704/6233/5716/7311/9972/11160/8021/129401/55746/55630/5693/8480/7314 44 Norwalk_virus R-HSA-9006931 Signaling by Nuclear Receptors 65/1313 299/10654 2.5541795432682516e-6 1.0636700715422485e-5 5.178732101151453e-6 5295/5170/27161/3725/596/5434/5590/1839/4893/6464/685/857/5290/7090/5241/347/5747/8204/207/2625/5594/2069/1027/3315/5481/6720/192670/5885/2100/4313/1950/2194/6667/2289/6714/2099/4609/10524/5467/10000/3320/2033/4846/595/192669/2066/2771/208/3326/7514/1025/1386/1956/5536/3169/3845/858/3265/26523/801/3480/2288/10728/10062/5595 65 Norwalk_virus R-HSA-199977 ER to Golgi Anterograde Transport 40/1313 154/10654 2.6156421635236084e-6 1.0856227173688289e-5 5.285613806944381e-6 10113/79861/11258/55291/1783/10382/93661/5861/55860/830/7277/10671/1780/1781/9570/8655/84516/1639/832/3998/10282/10121/81876/9527/7846/347733/51143/3630/10540/4905/6709/5537/10383/84790/378/1453/140735/829/51164/1778 40 Norwalk_virus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 24/1313 72/10654 2.679750296140597e-6 1.1085233725034936e-5 5.397111122753343e-6 6517/8773/5563/79861/71/7531/4627/7532/207/10382/2810/7277/7534/8766/7846/347733/208/6844/10383/84790/801/4218/7529/5879 24 Norwalk_virus R-HSA-6804760 Regulation of TP53 Activity through Methylation 11/1313 19/10654 2.8100999799834447e-6 1.15858274922241e-5 5.640837169122215e-6 7316/4194/56950/2033/7157/6233/7311/10419/133746/7314/4193 11 Norwalk_virus R-HSA-112043 PLC beta mediated events 20/1313 54/10654 2.8661161415025395e-6 1.175963885171439e-5 5.725461385880707e-6 818/815/5575/5567/817/5578/5594/5582/5573/10645/5566/84254/816/5613/2771/5577/5580/3710/801/814 20 Norwalk_virus R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 9/1313 13/10654 2.871209163633731e-6 1.175963885171439e-5 5.725461385880707e-6 7531/7532/2810/7534/983/995/1111/7465/7529 9 Norwalk_virus R-HSA-1433559 Regulation of KIT signaling 10/1313 16/10654 3.099760804469708e-6 1.265395775772009e-5 6.160881931321373e-6 5578/9306/6714/867/4067/2534/6654/2885/7525/3932 10 Norwalk_virus R-HSA-112040 G-protein mediated events 20/1313 55/10654 3.987194694379383e-6 1.622330693680267e-5 7.898704933818002e-6 818/815/5575/5567/817/5578/5594/5582/5573/10645/5566/84254/816/5613/2771/5577/5580/3710/801/814 20 Norwalk_virus R-HSA-76002 Platelet activation, signaling and aggregation 58/1313 262/10654 4.885074878020914e-6 1.9811692560862595e-5 9.645796284774699e-6 5295/5170/5590/351/1072/6464/5290/5579/5747/2316/207/3959/7422/5578/5594/5582/5908/10490/7277/5583/7534/1950/6714/3671/6647/1432/3920/226/4067/5588/3309/2335/2534/3690/408/55664/2768/1445/87/998/5894/2771/10487/6654/2885/1398/5580/3932/387/3710/5581/9564/10916/5660/801/967/5879/5595 58 Norwalk_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 18/1313 47/10654 5.157379649154266e-6 2.084790926579949e-5 1.0150303166859417e-5 8454/7090/55869/3280/6500/3091/10013/7316/9759/4609/10014/22938/2033/55294/3066/6233/7311/7314 18 Norwalk_virus R-HSA-354192 Integrin alphaIIb beta3 signaling 13/1313 27/10654 5.374704860733932e-6 2.158578877725181e-5 1.0509557452090877e-5 5170/6464/5747/207/5908/6714/2335/3690/1445/6654/2885/1398/9564 13 Norwalk_virus R-HSA-9006921 Integrin signaling 13/1313 27/10654 5.374704860733932e-6 2.158578877725181e-5 1.0509557452090877e-5 5170/6464/5747/207/5908/6714/2335/3690/1445/6654/2885/1398/9564 13 Norwalk_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 11/1313 20/10654 5.549161621098734e-6 2.221454700575332e-5 1.0815683431275633e-5 1147/11035/8737/8517/7316/329/6233/7311/7334/3551/7314 11 Norwalk_virus R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 16/1313 39/10654 6.051584267832962e-6 2.414796166038812e-5 1.1757012590069793e-5 10694/26224/2629/10575/10576/908/6774/26272/26270/6950/55294/26190/7157/10574/54461/22948 16 Norwalk_virus R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 8/1313 11/10654 6.099364059732972e-6 2.426061153246352e-5 1.1811858874111762e-5 6885/23118/7316/80216/10454/6233/7311/7314 8 Norwalk_virus R-HSA-399955 SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion 9/1313 14/10654 7.1573157570713925e-6 2.8377727969730343e-5 1.3816375465138658e-5 5361/10371/8829/55558/2534/91584/5362/5879/2242 9 Norwalk_virus R-HSA-162599 Late Phase of HIV Life Cycle 36/1313 139/10654 8.77104422036419e-6 3.466517795373236e-5 1.687757084307424e-5 23165/5434/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/7316/53371/23279/4927/9688/8731/79902/9883/23225/8086/6233/7514/1025/7311/9972/8021/129401/6829/1022/55746/22916/8480/7314 36 Norwalk_virus R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 13/1313 28/10654 8.904816692097877e-6 3.508215084093164e-5 1.7080584064374877e-5 10694/10575/10382/7277/10576/908/6950/7846/347733/10574/10383/84790/22948 13 Norwalk_virus R-HSA-1251985 Nuclear signaling by ERBB4 14/1313 32/10654 9.468733483256528e-6 3.706844874675505e-5 1.804766069861945e-5 1839/685/5241/2069/23118/23385/6714/2099/145957/3084/2066/9542/10718/5663 14 Norwalk_virus R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 14/1313 32/10654 9.468733483256528e-6 3.706844874675505e-5 1.804766069861945e-5 10694/79861/10575/10382/7277/10576/908/6950/7846/347733/10574/10383/84790/22948 14 Norwalk_virus R-HSA-5610787 Hedgehog 'off' state 31/1313 113/10654 1.0475665953072586e-5 4.088145109359459e-5 1.9904112072372278e-5 8454/8945/5684/5575/54903/5707/5567/1452/10382/6500/7277/5573/7316/5566/2932/5688/7846/347733/5686/5710/5577/5704/6233/5716/7311/10383/23322/84790/8481/5693/7314 31 Norwalk_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 30/1313 108/10654 1.1068209058128334e-5 4.3058455928329975e-5 2.0964038935375894e-5 5295/596/7412/7184/207/5292/7422/2625/4582/3091/6778/332/4313/4985/6774/1026/4609/4988/3717/3320/4843/2335/595/7157/3716/604/3312/7297/3569/4170 30 Norwalk_virus R-HSA-74751 Insulin receptor signalling cascade 19/1313 54/10654 1.204960351437317e-5 4.6729868629178445e-5 2.2751554004112502e-5 5295/5170/4893/6464/5290/3667/5594/2322/2260/5289/2261/3630/208/6654/2885/3845/2549/3265/5595 19 Norwalk_virus R-HSA-162587 HIV Life Cycle 38/1313 152/10654 1.2127719364988206e-5 4.688629199984537e-5 2.2827712462709397e-5 23165/5434/5903/55706/7175/9631/3159/348995/79023/57122/23636/10762/23511/4686/7316/53371/920/23279/4927/9688/8731/79902/9883/23225/8086/6233/7514/1025/7311/9972/8021/129401/6829/1022/55746/22916/8480/7314 38 Norwalk_virus R-HSA-73887 Death Receptor Signalling 36/1313 141/10654 1.2380966127677692e-5 4.771670485853421e-5 2.323201882081398e-5 1147/57142/6885/5584/7531/8737/55072/835/9530/23118/23385/841/8517/7316/4168/7128/329/843/836/23365/10616/8837/11108/10454/3066/3654/6654/6233/7311/387/5599/1540/3551/5663/7314/5879 36 Norwalk_virus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 12/1313 25/10654 1.296927922862933e-5 4.9675541736817895e-5 2.4185725397119027e-5 9252/5594/5528/5598/1432/6195/6196/5518/6197/5600/51231/5595 12 Norwalk_virus R-HSA-9006335 Signaling by Erythropoietin 12/1313 25/10654 1.296927922862933e-5 4.9675541736817895e-5 2.4185725397119027e-5 5295/4893/6464/5290/5335/4067/3717/6654/2885/3845/2549/3265 12 Norwalk_virus R-HSA-5654732 Negative regulation of FGFR3 signaling 13/1313 29/10654 1.4326724290796772e-5 5.4706045676550135e-5 2.663494653576469e-5 5594/7316/673/6714/8569/2261/867/6233/2885/7311/5518/7314/5595 13 Norwalk_virus R-HSA-5357905 Regulation of TNFR1 signaling 14/1313 33/10654 1.4590789450262517e-5 5.5543465361275414e-5 2.7042664334680938e-5 1147/8737/55072/841/8517/7316/7128/329/10616/6233/7311/1540/3551/7314 14 Norwalk_virus R-HSA-8948751 Regulation of PTEN stability and activity 22/1313 69/10654 1.5543432445091377e-5 5.898898979926116e-5 2.8720200300925324e-5 5684/1459/5707/10273/207/1460/7316/1457/5688/10000/5686/5728/2444/5710/5987/208/5704/6233/5716/7311/5693/7314 22 Norwalk_virus R-HSA-111447 Activation of BAD and translocation to mitochondria 9/1313 15/10654 1.5932555045741013e-5 5.9916063065953325e-5 2.9171568090128683e-5 596/7531/7532/207/2810/7534/10000/208/7529 9 Norwalk_virus R-HSA-937039 IRAK1 recruits IKK complex 9/1313 15/10654 1.5932555045741013e-5 5.9916063065953325e-5 2.9171568090128683e-5 1147/8517/7316/3654/6233/7311/7334/3551/7314 9 Norwalk_virus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 9/1313 15/10654 1.5932555045741013e-5 5.9916063065953325e-5 2.9171568090128683e-5 1147/8517/7316/3654/6233/7311/7334/3551/7314 9 Norwalk_virus R-HSA-111932 CaMK IV-mediated phosphorylation of CREB 8/1313 12/10654 1.631313673827859e-5 6.043164982747382e-5 2.9422593834318653e-5 818/815/817/10645/84254/816/801/814 8 Norwalk_virus R-HSA-210990 PECAM1 interactions 8/1313 12/10654 1.631313673827859e-5 6.043164982747382e-5 2.9422593834318653e-5 5335/6714/4067/2534/3690/7525/3685/3932 8 Norwalk_virus R-HSA-3371511 HSF1 activation 8/1313 12/10654 1.631313673827859e-5 6.043164982747382e-5 2.9422593834318653e-5 7531/1915/10013/7415/3320/3326/3297/10728 8 Norwalk_virus R-HSA-389359 CD28 dependent Vav1 pathway 8/1313 12/10654 1.631313673827859e-5 6.043164982747382e-5 2.9422593834318653e-5 5063/2534/998/2885/3932/5058/5062/5879 8 Norwalk_virus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 8/1313 12/10654 1.631313673827859e-5 6.043164982747382e-5 2.9422593834318653e-5 1147/8737/841/7706/8517/23586/843/3551 8 Norwalk_virus R-HSA-5655302 Signaling by FGFR1 in disease 15/1313 38/10654 2.0588880273144362e-5 7.604404886598855e-5 3.70238636490754e-5 5295/4893/5290/5335/9530/613/2260/6774/11064/6654/2885/11160/3845/2549/3265 15 Norwalk_virus R-HSA-8856688 Golgi-to-ER retrograde transport 34/1313 133/10654 2.0809640913439643e-5 7.663134828955073e-5 3.730980441766159e-5 79861/11258/1783/10382/93661/5861/55860/830/7277/10671/1780/5048/1781/22930/8655/84516/1639/832/25782/10121/81876/6836/7846/347733/51143/10540/4905/10383/84790/378/140735/829/51164/1778 34 Norwalk_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 14/1313 34/10654 2.2008535372991887e-5 8.080648638426903e-5 3.9342570240103845e-5 29110/9636/7706/7316/23586/7128/3661/9246/51191/6233/7311/9641/1540/7314 14 Norwalk_virus R-HSA-114452 Activation of BH3-only proteins 13/1313 30/10654 2.244420172956868e-5 8.192133631292567e-5 3.988536158753072e-5 596/7531/7532/207/2810/7534/8655/10000/7157/208/5599/140735/7529 13 Norwalk_virus R-HSA-2424491 DAP12 signaling 13/1313 30/10654 2.244420172956868e-5 8.192133631292567e-5 3.988536158753072e-5 5295/4893/6464/5290/5335/2534/695/6654/2885/3932/3845/3265/5879 13 Norwalk_virus R-HSA-8878159 Transcriptional regulation by RUNX3 27/1313 96/10654 2.353786623145087e-5 8.566126684231827e-5 4.170623619957648e-5 8463/5684/1499/1029/5707/3280/7316/9759/1026/6714/4609/22938/5688/5686/2033/595/5710/7157/5704/6233/5716/7311/3845/5693/3676/7314/4193 27 Norwalk_virus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 21/1313 66/10654 2.5003307104626097e-5 9.072837461064616e-5 4.4173278787489634e-5 5684/64344/112399/5707/84962/3091/7316/8994/5688/5686/5710/7428/8453/5704/6233/5716/7311/2034/54583/5693/7314 21 Norwalk_virus R-HSA-75153 Apoptotic execution phase 18/1313 52/10654 2.6286116320862907e-5 9.510516138248067e-5 4.630422209045668e-5 4000/1499/5747/841/7082/660/10134/329/999/5588/836/4137/5580/6709/6093/839/840/5062 18 Norwalk_virus R-HSA-1169091 Activation of NF-kappaB in B cells 21/1313 67/10654 3.22439334226582e-5 1.1632186446953147e-4 5.663408134824299e-5 8454/1147/8945/5684/6885/5579/5707/6500/8517/7316/5688/23291/5686/5710/5704/6233/5716/7311/3551/5693/7314 21 Norwalk_virus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 9/1313 16/10654 3.243186192737568e-5 1.166606975416615e-4 5.679905033200196e-5 5590/7316/7046/6233/7048/7311/56288/387/7314 9 Norwalk_virus R-HSA-182971 EGFR downregulation 13/1313 31/10654 3.431784625126628e-5 1.2308799768156488e-4 5.992833510260677e-5 1839/685/5782/2069/7316/1950/867/998/6233/2885/7311/1956/7314 13 Norwalk_virus R-HSA-2428924 IGF1R signaling cascade 18/1313 53/10654 3.526952538405359e-5 1.2613683285766716e-4 6.141273341558247e-5 5295/5170/4893/6464/5290/3667/2322/2260/5289/2261/8471/208/6654/2885/3845/2549/3265/3480 18 Norwalk_virus R-HSA-110056 MAPK3 (ERK1) activation 7/1313 10/10654 3.63667126933849e-5 1.285786052777512e-4 6.260156870896067e-5 5604/983/3717/3716/7297/3569/5595 7 Norwalk_virus R-HSA-390450 Folding of actin by CCT/TriC 7/1313 10/10654 3.63667126933849e-5 1.285786052777512e-4 6.260156870896067e-5 10694/10575/10576/908/6950/10574/22948 7 Norwalk_virus R-HSA-450341 Activation of the AP-1 family of transcription factors 7/1313 10/10654 3.63667126933849e-5 1.285786052777512e-4 6.260156870896067e-5 3725/5594/1432/1386/5599/5600/5595 7 Norwalk_virus R-HSA-74749 Signal attenuation 7/1313 10/10654 3.63667126933849e-5 1.285786052777512e-4 6.260156870896067e-5 6464/3667/5594/3630/6654/2885/5595 7 Norwalk_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 20/1313 63/10654 4.0243624893701814e-5 1.4188164344626123e-4 6.907847095988291e-5 1147/11035/5434/1499/8737/29110/81844/23220/147945/8517/6778/5591/7316/2033/22954/3661/6233/7311/3551/7314 20 Norwalk_virus R-HSA-1980143 Signaling by NOTCH1 22/1313 73/10654 4.1565222722503126e-005 1.4571311129555473e-4 7.094391270507523e-5 8454/7090/55869/3280/23220/6500/3091/10013/23385/7316/9759/4609/10014/22938/2033/408/55294/3066/6233/7311/5663/7314 22 Norwalk_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 22/1313 73/10654 4.1565222722503126e-005 1.4571311129555473e-4 7.094391270507523e-5 8454/5684/5707/10273/6500/7316/11059/2099/2932/5688/6502/2908/5686/55294/5710/5704/6233/5716/7311/1750/5693/7314 22 Norwalk_virus R-HSA-5619102 SLC transporter disorders 27/1313 99/10654 4.283925529428645e-5 1.497563825921394e-4 7.291247602348533e-5 23165/5903/55706/7175/9631/6559/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/682/8086/9972/8021/129401/55746/55630/8480 27 Norwalk_virus R-HSA-167044 Signalling to RAS 10/1313 20/10654 4.478311900388893e-5 1.5444615796261004e-4 7.519580531026606e-5 4893/6464/6714/1432/4914/6654/2885/3845/5600/3265 10 Norwalk_virus R-HSA-5213460 RIPK1-mediated regulated necrosis 10/1313 20/10654 4.478311900388893e-5 1.5444615796261004e-4 7.519580531026606e-5 11035/8737/841/7316/329/8837/197259/6233/7311/7314 10 Norwalk_virus R-HSA-5218859 Regulated Necrosis 10/1313 20/10654 4.478311900388893e-5 1.5444615796261004e-4 7.519580531026606e-5 11035/8737/841/7316/329/8837/197259/6233/7311/7314 10 Norwalk_virus R-HSA-8876384 Listeria monocytogenes entry into host cells 10/1313 20/10654 4.478311900388893e-5 1.5444615796261004e-4 7.519580531026606e-5 1499/7316/4233/6714/867/999/6233/2885/7311/7314 10 Norwalk_virus R-HSA-5358351 Signaling by Hedgehog 36/1313 149/10654 4.480307563782402e-5 1.5444615796261004e-4 7.519580531026606e-5 8454/8945/5684/5575/54903/5707/5567/1452/10382/6500/79577/7277/5573/8452/7316/7415/5566/2932/5688/7846/347733/5686/408/5710/5577/5704/6233/5716/7311/10383/23322/84790/8481/5693/5034/7314 36 Norwalk_virus R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 18/1313 54/10654 4.6879486318893985e-5 1.6115635047575467e-4 7.846282299765316e-5 5295/5170/4893/6464/5290/3667/2322/2260/5289/2261/8471/208/6654/2885/3845/2549/3265/3480 18 Norwalk_virus R-HSA-69242 S Phase 38/1313 161/10654 4.828703733035355e-5 1.655365009032286e-4 8.059540397680413e-5 8454/1017/4172/1019/5684/5707/207/1027/6500/5925/4149/5885/7316/4174/5753/1026/4171/4609/2932/5688/6502/10000/5686/595/5710/208/5704/6233/5716/51343/23595/7311/29882/7465/1163/1022/5693/7314 38 Norwalk_virus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 19/1313 59/10654 4.9993410933652605e-5 1.7091411286133024e-4 8.321362295466609e-5 8454/1147/8945/5684/5707/6500/7316/9020/5688/23291/5686/5710/9040/5704/6233/5716/7311/5693/7314 19 Norwalk_virus R-HSA-5626467 RHO GTPases activate IQGAPs 13/1313 32/10654 5.131987077674682e-5 1.7496692207127142e-4 8.518683003427611e-5 79861/71/1499/10382/7277/7846/999/347733/998/10383/84790/801/5879 13 Norwalk_virus R-HSA-163200 Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 31/1313 123/10654 6.359643173493793e-5 2.1622786789878893e-4 1.0527570819280282e-4 4723/1329/4700/1345/4719/4704/4710/4724/4729/7386/4714/84987/4718/4701/7385/4728/4725/4695/10128/4731/55967/4705/7381/4726/7384/54539/4698/1340/1327/4720/51079 31 Norwalk_virus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 19/1313 60/10654 6.48161391378373e-5 2.1857833877732635e-4 1.0642009114736446e-4 8454/1147/8945/5684/5707/6500/7316/9020/5688/23291/5686/5710/9040/5704/6233/5716/7311/5693/7314 19 Norwalk_virus R-HSA-5610783 Degradation of GLI2 by the proteasome 19/1313 60/10654 6.48161391378373e-5 2.1857833877732635e-4 1.0642009114736446e-4 8454/8945/5684/5707/5567/1452/6500/7316/5566/2932/5688/5686/5710/5704/6233/5716/7311/5693/7314 19 Norwalk_virus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 19/1313 60/10654 6.48161391378373e-5 2.1857833877732635e-4 1.0642009114736446e-4 8454/8945/5684/5707/5567/1452/6500/7316/5566/2932/5688/5686/5710/5704/6233/5716/7311/5693/7314 19 Norwalk_virus R-HSA-400253 Circadian Clock 21/1313 70/10654 6.651152290867033e-5 2.2368780468742515e-4 1.0890775680951868e-4 8454/26224/8945/8204/1454/4862/6500/3091/1408/6720/5465/406/7316/2908/2033/6233/7311/1386/23411/1453/7314 21 Norwalk_virus R-HSA-5654726 Negative regulation of FGFR1 signaling 13/1313 33/10654 7.519377363896175e-5 2.515163514672869e-4 1.224567502796749e-4 5594/2260/7316/673/6714/8569/867/6233/2885/7311/5518/7314/5595 13 Norwalk_virus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 24/1313 86/10654 7.539410374361864e-5 2.515163514672869e-4 1.224567502796749e-4 8454/1017/8945/5684/5707/9212/6500/7316/983/6790/5688/6502/5686/5710/4751/5704/6233/5716/51343/7311/5347/29882/5693/7314 24 Norwalk_virus R-HSA-453276 Regulation of mitotic cell cycle 24/1313 86/10654 7.539410374361864e-5 2.515163514672869e-4 1.224567502796749e-4 8454/1017/8945/5684/5707/9212/6500/7316/983/6790/5688/6502/5686/5710/4751/5704/6233/5716/51343/7311/5347/29882/5693/7314 24 Norwalk_virus R-HSA-389513 CTLA4 inhibitory signaling 10/1313 21/10654 7.607999321002182e-5 2.531240524762388e-4 1.232394979612037e-4 207/5528/6714/4067/10000/2534/208/7525/3932/5518 10 Norwalk_virus R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission 45/1313 206/10654 7.72544195949215e-5 2.563442104740577e-4 1.248073088868138e-4 818/5170/5563/815/4893/79861/5579/5575/5567/817/5578/10382/5594/5582/7277/5573/10645/6714/5566/84254/27330/7846/347733/3084/6195/4137/816/2066/4905/5613/2771/5577/163/6196/5562/10383/84790/6197/3845/3265/801/814/5879/5595/4193 45 Norwalk_virus R-HSA-169893 Prolonged ERK activation events 8/1313 14/10654 7.870409432522891e-5 2.590763423278756e-4 1.261375126139366e-4 5604/5594/673/57498/4914/1398/7529/5595 8 Norwalk_virus R-HSA-418885 DCC mediated attractive signaling 8/1313 14/10654 7.870409432522891e-5 2.590763423278756e-4 1.261375126139366e-4 5747/1793/6714/2534/998/8976/1630/5879 8 Norwalk_virus R-HSA-9027284 Erythropoietin activates RAS 8/1313 14/10654 7.870409432522891e-5 2.590763423278756e-4 1.261375126139366e-4 4893/6464/4067/3717/6654/2885/3845/3265 8 Norwalk_virus R-HSA-9619483 Activation of AMPK downstream of NMDARs 12/1313 29/10654 8.062049660974493e-5 2.6408655197154385e-4 1.2857685298924145e-4 5563/79861/10382/7277/10645/7846/347733/4137/5562/10383/84790/801 12 Norwalk_virus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 18/1313 56/10654 8.065173505013306e-5 2.6408655197154385e-4 1.2857685298924145e-4 3303/5684/5707/3315/26986/7316/5688/5686/1981/5710/5704/6233/5716/7311/3304/3312/5693/7314 18 Norwalk_virus R-HSA-5654708 Downstream signaling of activated FGFR3 11/1313 25/10654 8.174707172558172e-5 2.662680210274197e-4 1.2963895336506122e-4 5295/4893/6464/5290/5335/2261/6654/2885/3845/2549/3265 11 Norwalk_virus R-HSA-937041 IKK complex recruitment mediated by RIP1 11/1313 25/10654 8.174707172558172e-5 2.662680210274197e-4 1.2963895336506122e-4 1147/11035/8737/8517/7316/329/6233/7311/7334/3551/7314 11 Norwalk_virus R-HSA-373760 L1CAM interactions 30/1313 119/10654 8.254411159616434e-5 2.681603206566491e-4 1.3056026469054379e-4 9252/79861/71/5604/1459/10382/5594/1460/7277/2260/8829/1457/6714/27330/7846/347733/3690/6195/6709/3685/163/6196/10383/1956/84790/6197/3312/5058/5879/5595 30 Norwalk_virus R-HSA-877300 Interferon gamma signaling 25/1313 92/10654 8.675830357897355e-5 2.8111502543474195e-4 1.368675725005657e-4 818/815/23321/4281/7412/817/3123/7706/3126/2634/51127/3122/3659/3717/3458/816/3661/10346/5371/5580/3716/10107/3127/3125/3660 25 Norwalk_virus R-HSA-8851805 MET activates RAS signaling 7/1313 11/10654 8.93345728022756e-5 2.872129659264871e-4 1.3983650065041233e-4 4893/6464/4233/6654/2885/3845/3265 7 Norwalk_virus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 7/1313 11/10654 8.93345728022756e-5 2.872129659264871e-4 1.3983650065041233e-4 6885/23118/7316/10454/6233/7311/7314 7 Norwalk_virus R-HSA-9614399 Regulation of localization of FOXO transcription factors 7/1313 11/10654 8.93345728022756e-5 2.872129659264871e-4 1.3983650065041233e-4 7532/207/2810/7534/10000/208/7529 7 Norwalk_virus R-HSA-437239 Recycling pathway of L1 16/1313 47/10654 9.21133965741795e-5 2.953817187301208e-4 1.4381365329410863e-4 9252/79861/71/10382/5594/7277/6714/27330/7846/347733/6195/163/6196/10383/84790/6197 16 Norwalk_virus R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 14/1313 38/10654 9.484212045423788e-5 3.0334812238069385e-4 1.476922874138159e-4 1072/9049/5908/3313/6175/6647/6950/5306/3458/998/6648/4282/5062/829 14 Norwalk_virus R-HSA-5689880 Ub-specific processing proteases 47/1313 220/10654 9.598834276544715e-5 3.06225021521645e-4 1.4909297455653272e-4 23032/5684/6885/51651/7419/5707/8737/2625/9817/91833/1080/3091/8517/7416/7316/7417/9738/8678/4609/4194/23586/5688/329/7046/6502/5686/408/5728/5710/10454/7157/10869/10868/63891/5704/6233/5716/9804/7311/367/23770/8607/1540/5693/154/7314/4193 47 Norwalk_virus R-HSA-9013694 Signaling by NOTCH4 23/1313 82/10654 9.709310643262324e-5 3.0895524380227034e-4 1.504222485622827e-4 8454/5684/5707/207/3280/6500/23385/7534/7316/22938/5688/5686/2033/55294/5710/5704/6233/2324/5716/7311/5693/5663/7314 23 Norwalk_virus R-HSA-2428928 IRS-related events triggered by IGF1R 17/1313 52/10654 9.977539324057346e-5 3.166784220244288e-4 1.5418246256586126e-4 5295/5170/4893/5290/3667/2322/2260/5289/2261/8471/208/6654/2885/3845/2549/3265/3480 17 Norwalk_virus R-HSA-948021 Transport to the Golgi and subsequent modification 41/1313 185/10654 1.1330849472973786e-4 3.5871388255001195e-4 1.7464843172628768e-4 10113/79861/11258/55291/1783/10382/93661/5861/55860/830/7277/10671/1780/1781/9570/8655/84516/1639/832/3998/10282/10121/81876/9527/7846/347733/51143/3630/10540/4905/2683/6709/5537/10383/84790/378/1453/140735/829/51164/1778 41 Norwalk_virus R-HSA-5655332 Signaling by FGFR3 in disease 10/1313 22/10654 1.2413789912562703e-4 3.910028751647288e-4 1.9036909991480074e-4 5295/4893/5290/5335/2261/6654/2885/3845/2549/3265 10 Norwalk_virus R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 10/1313 22/10654 1.2413789912562703e-4 3.910028751647288e-4 1.9036909991480074e-4 5295/4893/5290/5335/2261/6654/2885/3845/2549/3265 10 Norwalk_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 22/1313 78/10654 1.2497805427147027e-4 3.9265257050859393e-4 1.9117229354250221e-4 1147/351/8737/29110/9636/841/7706/8517/7316/23586/7128/843/2033/3661/9246/51191/6233/7311/9641/1540/3551/7314 22 Norwalk_virus R-HSA-69615 G1/S DNA Damage Checkpoints 20/1313 68/10654 1.335847293818913e-4 4.155243716367582e-4 2.0230797686034117e-4 1017/5684/1029/5707/1027/7316/1026/4194/5688/5686/5710/1111/7157/5704/6233/5716/7311/5693/7314/4193 20 Norwalk_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 18/1313 58/10654 1.3426694039189366e-4 4.155243716367582e-4 2.0230797686034117e-4 8454/55869/3280/6500/10013/23385/7316/9759/4609/10014/22938/2033/55294/3066/6233/7311/5663/7314 18 Norwalk_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 18/1313 58/10654 1.3426694039189366e-4 4.155243716367582e-4 2.0230797686034117e-4 8454/55869/3280/6500/10013/23385/7316/9759/4609/10014/22938/2033/55294/3066/6233/7311/5663/7314 18 Norwalk_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 18/1313 58/10654 1.3426694039189366e-4 4.155243716367582e-4 2.0230797686034117e-4 8454/55869/3280/6500/10013/23385/7316/9759/4609/10014/22938/2033/55294/3066/6233/7311/5663/7314 18 Norwalk_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 18/1313 58/10654 1.3426694039189366e-4 4.155243716367582e-4 2.0230797686034117e-4 8454/55869/3280/6500/10013/23385/7316/9759/4609/10014/22938/2033/55294/3066/6233/7311/5663/7314 18 Norwalk_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 18/1313 58/10654 1.3426694039189366e-4 4.155243716367582e-4 2.0230797686034117e-4 8454/55869/3280/6500/10013/23385/7316/9759/4609/10014/22938/2033/55294/3066/6233/7311/5663/7314 18 Norwalk_virus R-HSA-1226099 Signaling by FGFR in disease 19/1313 63/10654 1.3518800675269604e-4 4.17334120348497e-4 2.0318909629758457e-4 5295/5434/4893/5290/5335/9530/613/2260/4686/6774/2261/11064/6654/2885/11160/3845/2549/3265/22916 19 Norwalk_virus R-HSA-5578749 Transcriptional regulation by small RNAs 27/1313 106/10654 1.527469516868051e-4 4.703696452687968e-4 2.2901070985562527e-4 23165/27161/5434/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/26523/55746/8480 27 Norwalk_virus R-HSA-6806834 Signaling by MET 22/1313 79/10654 1.5338260511992856e-4 4.7115795285601814e-4 2.2939451625544297e-4 5295/4893/6464/5290/5747/5908/7316/6774/4233/6714/867/2335/6654/6233/2885/1398/7311/3845/2549/3265/7314/5879 22 Norwalk_virus R-HSA-9604323 Negative regulation of NOTCH4 signaling 17/1313 54/10654 1.68535664808407e-4 5.164265679684768e-4 2.514346240416521e-4 8454/5684/5707/207/6500/7534/7316/5688/5686/55294/5710/5704/6233/5716/7311/5693/7314 17 Norwalk_virus R-HSA-5339562 Uptake and actions of bacterial toxins 12/1313 31/10654 1.7314375442511562e-4 5.279395558760897e-4 2.5703999751717675e-4 6804/1839/5606/5604/1938/6616/3320/5609/3326/6844/6843/801 12 Norwalk_virus R-HSA-5654733 Negative regulation of FGFR4 signaling 12/1313 31/10654 1.7314375442511562e-4 5.279395558760897e-4 2.5703999751717675e-4 5594/7316/673/6714/8569/867/6233/2885/7311/5518/7314/5595 12 Norwalk_virus R-HSA-2559583 Cellular Senescence 42/1313 195/10654 1.8360058309933863e-4 5.584517735938217e-4 2.718956003586697e-4 1017/7014/3725/1019/5606/9448/3159/1029/2146/5594/1027/5925/7013/50488/192670/7316/6774/1026/6667/4194/5598/1432/10524/1021/6195/192669/7157/5609/6233/51343/6196/7311/6197/29882/5599/5600/4217/26523/3569/7314/5595/4193 42 Norwalk_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 7/1313 12/10654 1.9156458329187161e-4 5.812509727755811e-4 2.8299593568275466e-4 29110/7316/3661/6233/7311/9641/7314 7 Norwalk_virus R-HSA-112409 RAF-independent MAPK1/3 activation 10/1313 23/10654 1.954994527395864e-4 5.917434654873823e-4 2.881044566688642e-4 5604/5594/1852/983/3717/3716/1843/7297/3569/5595 10 Norwalk_virus R-HSA-111885 Opioid Signalling 24/1313 91/10654 1.972616895633879e-4 5.956247122826384e-4 2.8999413448427367e-4 818/815/5575/5567/817/5578/5594/5582/5573/5528/10645/5566/84254/4988/816/5613/2771/5577/5580/5518/3710/801/1020/814 24 Norwalk_virus R-HSA-9006936 Signaling by TGF-beta family members 26/1313 102/10654 1.9841685805954348e-4 5.97658545757023e-4 2.9098435494680116e-4 5590/10273/4738/269/130399/54778/7316/91/93/6667/4609/22938/867/7046/94/9040/657/6233/7514/7048/1025/7311/56288/9110/387/7314 26 Norwalk_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 12/1313 32/10654 2.4623808461413766e-4 7.399066900875178e-4 3.602412656263924e-4 10273/4738/7316/867/7046/9040/6233/7514/7048/7311/9110/7314 12 Norwalk_virus R-HSA-68949 Orc1 removal from chromatin 20/1313 71/10654 2.5496513780805626e-4 7.642795556033763e-4 3.721077780366751e-4 8454/1017/4172/5684/5707/6500/7316/4174/4171/5688/6502/5686/5710/5704/6233/5716/23595/7311/5693/7314 20 Norwalk_virus R-HSA-69563 p53-Dependent G1 DNA Damage Response 19/1313 66/10654 2.655283184567503e-4 7.921169307808344e-4 3.856610698233165e-4 1017/5684/1029/5707/1027/7316/1026/4194/5688/5686/5710/7157/5704/6233/5716/7311/5693/7314/4193 19 Norwalk_virus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 19/1313 66/10654 2.655283184567503e-4 7.921169307808344e-4 3.856610698233165e-4 1017/5684/1029/5707/1027/7316/1026/4194/5688/5686/5710/7157/5704/6233/5716/7311/5693/7314/4193 19 Norwalk_virus R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 8/1313 16/10654 2.684541307904832e-4 7.97013340456913e-4 3.880450039630758e-4 5295/5170/6464/5290/4067/2534/6654/2885 8 Norwalk_virus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 8/1313 16/10654 2.684541307904832e-4 7.97013340456913e-4 3.880450039630758e-4 6885/23118/7316/3656/10454/6233/7311/7314 8 Norwalk_virus R-HSA-69481 G2/M Checkpoints 37/1313 168/10654 2.7353958962981204e-4 8.101733430324505e-4 3.944522659151165e-4 1017/4172/5684/5883/7531/51512/5707/7532/2810/545/9133/7534/7316/4174/983/641/4171/3364/10524/5688/5686/995/5710/1111/7157/5704/6233/5716/672/23595/7311/7334/7465/5810/5693/7529/7314 37 Norwalk_virus R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 10/1313 24/10654 2.9836703110577346e-4 8.816035371482497e-4 4.2922976404690224e-4 5590/5579/5578/5594/5289/1432/5580/5600/5879/5595 10 Norwalk_virus R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 14/1313 42/10654 3.221083432884241e-4 9.494927648953308e-4 4.622832580261419e-4 10694/6000/1459/10575/1460/10576/908/8786/1457/6950/2771/10574/22948/9628 14 Norwalk_virus R-HSA-202433 Generation of second messenger molecules 12/1313 33/10654 3.4397769088566685e-4 0.0010115552473675654 4.92499861732035e-4 5335/3123/3126/3122/920/5063/3702/3932/3127/3125/5058/5062 12 Norwalk_virus R-HSA-209543 p75NTR recruits signalling complexes 7/1313 13/10654 3.709330061317269e-4 0.0010882455333557283 5.298383613776566e-4 5584/7316/3654/6233/7311/3551/7314 7 Norwalk_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 20/1313 73/10654 3.8178827238060227e-4 0.0011165179674976523 5.436034720248124e-4 5590/10273/4738/54778/7316/6667/4609/22938/867/7046/9040/6233/7514/7048/1025/7311/56288/9110/387/7314 20 Norwalk_virus R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 26/1313 106/10654 3.823691669512508e-4 0.0011165179674976523 5.436034720248124e-4 1839/685/10618/4738/2069/1080/29978/7316/1950/920/10980/867/9341/408/10987/6233/2885/6844/163/7311/6845/1956/8533/8673/154/7314 26 Norwalk_virus R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic 42/1313 202/10654 4.06315765022012e-4 0.0011836569586674106 5.762916953858041e-4 79861/11258/10618/1783/27333/10382/93661/5861/55860/830/7277/10671/1780/5048/1781/9570/22930/8655/22836/84516/1639/832/25782/10121/9367/81876/9341/6836/9527/9342/7846/347733/51143/10540/4905/10383/84790/378/140735/829/51164/1778 42 Norwalk_virus R-HSA-112399 IRS-mediated signalling 15/1313 48/10654 4.399985835024446e-4 0.0012787780846054654 6.226036902019062e-4 5295/5170/4893/5290/3667/2322/2260/5289/2261/208/6654/2885/3845/2549/3265 15 Norwalk_virus R-HSA-400685 Sema4D in semaphorin signaling 10/1313 25/10654 4.42780337359239e-4 0.0012808634001464233 6.236189759396472e-4 3984/4627/3985/2064/4233/23365/9475/6093/387/5879 10 Norwalk_virus R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 10/1313 25/10654 4.42780337359239e-4 0.0012808634001464233 6.236189759396472e-4 1017/2305/9133/983/995/7514/5518/5347/7465/1022 10 Norwalk_virus R-HSA-72306 tRNA processing 26/1313 107/10654 4.4708193764169324e-4 0.0012902992665426542 6.282130531366756e-4 23165/5903/55706/7175/9631/3028/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/112858/9883/23225/8086/9972/8021/129401/55746/8480 26 Norwalk_virus R-HSA-8934593 Regulation of RUNX1 Expression and Activity 8/1313 17/10654 4.5251511429192473e-4 0.001299933464898793 6.329036929911424e-4 27161/192670/6714/1021/595/192669/5371/26523 8 Norwalk_virus R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 8/1313 17/10654 4.5251511429192473e-4 0.001299933464898793 6.329036929911424e-4 6885/23118/7316/3656/10454/6233/7311/7314 8 Norwalk_virus R-HSA-442729 CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde 6/1313 10/10654 4.6772853595201887e-4 0.0013380809114642022 6.514766895800944e-4 818/10645/84254/816/801/814 6 Norwalk_virus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 9/1313 21/10654 4.6795093922277504e-4 0.0013380809114642022 6.514766895800944e-4 1147/11035/8737/29110/23220/147945/8517/3661/3551 9 Norwalk_virus R-HSA-5654727 Negative regulation of FGFR2 signaling 12/1313 34/10654 4.726284484109441e-4 0.0013483492056965095 6.56476054175153e-4 5594/7316/673/6714/8569/867/6233/2885/7311/5518/7314/5595 12 Norwalk_virus R-HSA-76009 Platelet Aggregation (Plug Formation) 13/1313 39/10654 5.236157389002242e-4 0.0014903833302182987 7.256287641929712e-4 5170/6464/5747/207/5908/6714/2335/3690/1445/6654/2885/1398/9564 13 Norwalk_virus R-HSA-3928663 EPHA-mediated growth cone collapse 11/1313 30/10654 5.579022250648139e-4 0.0015843401860536246 7.713739062681036e-4 4627/2041/6714/4067/2043/2534/9475/7525/6093/387/1969 11 Norwalk_virus R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 7/1313 14/10654 6.631619179382237e-4 0.001874678679182997 9.127321445786847e-4 5594/5861/9133/983/81876/5347/5595 7 Norwalk_virus R-HSA-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase 7/1313 14/10654 6.631619179382237e-4 0.001874678679182997 9.127321445786847e-4 5575/5567/5573/5566/5613/5577/801 7 Norwalk_virus R-HSA-5610780 Degradation of GLI1 by the proteasome 17/1313 60/10654 6.736360742765007e-4 0.0018999599276753121 9.250409249634245e-4 8454/8945/5684/5707/5567/6500/7316/5566/5688/5686/5710/5704/6233/5716/7311/5693/7314 17 Norwalk_virus R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 16/1313 55/10654 6.995260625151377e-4 0.0019640539447540405 9.56246629873039e-4 8454/8945/5684/5707/6500/7316/5688/5686/5710/5704/6233/5716/51343/7311/5693/7314 16 Norwalk_virus R-HSA-8941858 Regulation of RUNX3 expression and activity 16/1313 55/10654 6.995260625151377e-4 0.0019640539447540405 9.56246629873039e-4 5684/1029/5707/7316/6714/5688/5686/2033/5710/5704/6233/5716/7311/5693/7314/4193 16 Norwalk_virus R-HSA-446203 Asparagine N-linked glycosylation 57/1313 304/10654 7.048764931987327e-4 0.001964384330342545 9.564074859973881e-4 10113/79861/11258/55291/1783/1650/10382/93661/821/5861/55860/54187/830/811/7277/10671/1780/1781/7316/9570/140838/8655/84061/84516/1639/832/3998/10282/10121/7415/81876/9527/7846/5476/347733/51143/3630/10540/6185/4905/2683/6233/6709/85365/5537/7311/10383/84790/378/2720/1453/140735/4758/829/7314/51164/1778 57 Norwalk_virus R-HSA-5205685 Pink/Parkin Mediated Mitophagy 9/1313 22/10654 7.059753515977236e-4 0.001964384330342545 9.564074859973881e-4 65018/10452/7416/100188893/7316/6233/9804/7311/7314 9 Norwalk_virus R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 9/1313 22/10654 7.059753515977236e-4 0.001964384330342545 9.564074859973881e-4 4000/3725/351/7531/823/995/6648/8851/1020 9 Norwalk_virus R-HSA-8863678 Neurodegenerative Diseases 9/1313 22/10654 7.059753515977236e-4 0.001964384330342545 9.564074859973881e-4 4000/3725/351/7531/823/995/6648/8851/1020 9 Norwalk_virus R-HSA-373752 Netrin-1 signaling 15/1313 50/10654 7.139279588898248e-4 0.001982068449624771 9.650174223543142e-4 5335/5747/1793/6714/1432/5588/2534/5306/998/8976/1630/5599/5600/5058/5879 15 Norwalk_virus R-HSA-210993 Tie2 Signaling 8/1313 18/10654 7.27030209399593e-4 0.0020094532068260468 9.783503462556945e-4 5295/4893/6464/5290/6654/2885/3845/3265 8 Norwalk_virus R-HSA-5675482 Regulation of necroptotic cell death 8/1313 18/10654 7.27030209399593e-4 0.0020094532068260468 9.783503462556945e-4 8737/841/7316/329/8837/6233/7311/7314 8 Norwalk_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 21/1313 82/10654 7.384236894681377e-4 0.0020364084413999088 9.914741467946459e-4 8454/8945/5684/7090/1499/5707/1452/6500/5528/7316/2932/5688/5686/5710/5704/6233/5716/7311/5518/5693/7314 21 Norwalk_virus R-HSA-3858494 Beta-catenin independent WNT signaling 32/1313 146/10654 7.512489894811099e-4 0.002067184026487932 0.0010064579763383293 27161/815/5684/6885/5579/1499/4772/5707/5578/5582/192670/7316/5688/5686/5710/192669/23513/5704/6233/5716/163/7311/387/3710/5593/3845/26523/801/5693/4920/7314/5879 32 Norwalk_virus R-HSA-5654687 Downstream signaling of activated FGFR1 11/1313 31/10654 7.695193839166513e-4 0.002112773352744611 0.0010286542300143406 5295/4893/6464/5290/5335/2260/6654/2885/3845/2549/3265 11 Norwalk_virus R-HSA-1236974 ER-Phagosome pathway 21/1313 83/10654 8.759990321537571e-4 0.002399811918107754 0.0011684058195800084 1147/8773/5684/5707/6890/811/8517/7316/5688/9341/5686/5710/695/5704/6233/5716/7311/3551/8673/5693/7314 21 Norwalk_virus R-HSA-8853659 RET signaling 13/1313 41/10654 8.97137030199407e-4 0.002449267358517774 0.0011924843833828426 5295/6464/5290/5335/5567/5578/6714/5566/5598/5979/6654/2885/2549 13 Norwalk_virus R-HSA-3928665 EPH-ephrin mediated repulsion of cells 15/1313 51/10654 8.979989106572015e-4 0.002449267358517774 0.0011924843833828426 71/23385/4313/2051/2041/6714/4067/2043/2047/2534/7525/163/5663/1969/5879 15 Norwalk_virus R-HSA-5654716 Downstream signaling of activated FGFR4 10/1313 27/10654 9.064401831075145e-4 0.0024668690070974242 0.0012010541669060788 5295/4893/6464/5290/5335/6654/2885/3845/2549/3265 10 Norwalk_virus R-HSA-1059683 Interleukin-6 signaling 6/1313 11/10654 9.218012917317108e-4 0.002481465082514215 0.001208160615262021 6774/867/3717/3716/7297/3569 6 Norwalk_virus R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 6/1313 11/10654 9.218012917317108e-4 0.002481465082514215 0.001208160615262021 64344/7422/3091/2033/2034/405 6 Norwalk_virus R-HSA-376172 DSCAM interactions 6/1313 11/10654 9.218012917317108e-4 0.002481465082514215 0.001208160615262021 1432/1630/5599/5600/5058/5879 6 Norwalk_virus R-HSA-8875555 MET activates RAP1 and RAC1 6/1313 11/10654 9.218012917317108e-4 0.002481465082514215 0.001208160615262021 5908/4233/2885/1398/2549/5879 6 Norwalk_virus R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 6/1313 11/10654 9.218012917317108e-4 0.002481465082514215 0.001208160615262021 4893/4915/6654/2885/3845/3265 6 Norwalk_virus R-HSA-69541 Stabilization of p53 16/1313 57/10654 0.0010725026225526682 0.0028808999017053273 0.0014026350087610656 5684/1029/5707/7316/4194/5688/5686/5710/7157/5704/6233/5716/7311/5693/7314/4193 16 Norwalk_virus R-HSA-69052 Switching of origins to a post-replicative state 22/1313 90/10654 0.0010963882619596092 0.0029386994235245678 0.001430776088131899 8454/1017/4172/5684/5707/6500/7316/4174/4171/5688/6502/5686/5710/5704/6233/5716/51343/23595/7311/29882/5693/7314 22 Norwalk_virus R-HSA-354194 GRB2:SOS provides linkage to MAPK signaling for Integrins 7/1313 15/10654 0.0011117909743201075 0.002953950613392298 0.0014382014946241817 5747/5908/6714/2335/3690/6654/2885 7 Norwalk_virus R-HSA-372708 p130Cas linkage to MAPK signaling for integrins 7/1313 15/10654 0.0011117909743201075 0.002953950613392298 0.0014382014946241817 5747/5908/6714/2335/3690/1398/9564 7 Norwalk_virus R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 7/1313 15/10654 0.0011117909743201075 0.002953950613392298 0.0014382014946241817 7316/4233/867/6233/2885/7311/7314 7 Norwalk_virus R-HSA-1428517 The citric acid (TCA) cycle and respiratory electron transport 36/1313 174/10654 0.0011197820773065346 0.002953950613392298 0.0014382014946241817 4723/1329/4700/1345/4719/4704/4710/4724/4729/7386/7416/4714/84987/4718/4701/50/7385/3939/4728/4725/4695/5467/682/10128/4731/55967/4705/7381/4726/7384/54539/4698/1340/1327/4720/51079 36 Norwalk_virus R-HSA-180534 Vpu mediated degradation of CD4 15/1313 52/10654 0.0011206584601369898 0.002953950613392298 0.0014382014946241817 8945/5684/5707/6500/7316/920/5688/5686/5710/5704/6233/5716/7311/5693/7314 15 Norwalk_virus R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 15/1313 52/10654 0.0011206584601369898 0.002953950613392298 0.0014382014946241817 1019/5684/5707/7316/2932/5688/5686/595/5710/5704/6233/5716/7311/5693/7314 15 Norwalk_virus R-HSA-3928664 Ephrin signaling 8/1313 19/10654 0.0011211206598773346 0.002953950613392298 0.0014382014946241817 2051/6714/2047/5063/2534/5058/5062/5879 8 Norwalk_virus R-HSA-8876725 Protein methylation 8/1313 19/10654 0.0011211206598773346 0.002953950613392298 0.0014382014946241817 1938/1915/79091/7415/79823/3312/801/6187 8 Norwalk_virus R-HSA-112315 Transmission across Chemical Synapses 51/1313 272/10654 0.0013143704591724538 0.003455791821680117 0.001682534887522276 6804/818/5170/5563/80331/815/4893/79861/5579/5575/5567/817/5578/10382/5594/5582/7277/5573/6616/10645/6714/5566/84254/27330/7846/347733/3084/6195/4137/816/1103/2066/4905/5613/2771/5577/6844/163/6196/5562/10383/84790/6197/3845/3265/3312/801/814/5879/5595/4193 51 Norwalk_virus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 20/1313 80/10654 0.0013496678644756245 0.00354109475647833 0.001724066661197304 8454/1017/8945/5684/5707/6500/7316/983/5688/5686/5710/5704/6233/5716/51343/7311/5347/29882/5693/7314 20 Norwalk_virus R-HSA-2871809 FCERI mediated Ca+2 mobilization 11/1313 33/10654 0.00139343982274125 0.003648225358695973 0.0017762257567254668 6464/4773/5335/4772/4067/695/6654/2885/3702/3710/801 11 Norwalk_virus R-HSA-5696394 DNA Damage Recognition in GG-NER 12/1313 38/10654 0.0014598409177485503 0.003814026481949371 0.0018569499984214248 8450/7316/10980/4798/10987/1069/6233/7311/8533/8607/7314/8451 12 Norwalk_virus R-HSA-2172127 DAP12 interactions 13/1313 43/10654 0.001471579753932022 0.0038310066404288043 0.0018652171946275363 5295/4893/6464/5290/5335/2534/695/6654/2885/3932/3845/3265/5879 13 Norwalk_virus R-HSA-5627123 RHO GTPases activate PAKs 9/1313 24/10654 0.0014756012684326901 0.0038310066404288043 0.0018652171946275363 3984/4627/2316/5063/998/5058/801/5062/5879 9 Norwalk_virus R-HSA-8940973 RUNX2 regulates osteoblast differentiation 9/1313 24/10654 0.0014756012684326901 0.0038310066404288043 0.0018652171946275363 25/5594/3280/5925/10013/6714/7525/367/5595 9 Norwalk_virus R-HSA-8856828 Clathrin-mediated endocytosis 31/1313 146/10654 0.0015564390925983228 0.004032444496690019 0.0019632920319776668 5869/1839/685/71/10618/4738/2069/1080/29978/7316/1950/920/10980/867/9341/408/10987/5878/8976/6233/2885/6844/163/7311/6845/1956/8533/3312/8673/154/7314 31 Norwalk_virus R-HSA-157118 Signaling by NOTCH 45/1313 235/10654 0.0015949907081432163 0.0041237155600119405 0.0020077295317416804 8454/27161/3725/5684/7090/5584/55869/5707/207/3280/23220/6500/3091/10013/23385/192670/7534/488/7316/1950/9759/4609/10014/22938/5688/5686/2033/408/595/55294/5710/192669/3066/7157/2683/5704/6233/2324/5716/7311/1956/26523/5693/5663/7314 45 Norwalk_virus R-HSA-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation 6/1313 12/10654 0.0016520380001715483 0.004218475634182904 0.002053865739871061 6697/207/3320/4846/5593/801 6 Norwalk_virus R-HSA-170968 Frs2-mediated activation 6/1313 12/10654 0.0016520380001715483 0.004218475634182904 0.002053865739871061 5604/5594/673/4914/7529/5595 6 Norwalk_virus R-HSA-2029481 FCGR activation 6/1313 12/10654 0.0016520380001715483 0.004218475634182904 0.002053865739871061 2268/3055/6714/4067/2534/7525 6 Norwalk_virus R-HSA-264870 Caspase-mediated cleavage of cytoskeletal proteins 6/1313 12/10654 0.0016520380001715483 0.004218475634182904 0.002053865739871061 841/836/4137/6709/839/840 6 Norwalk_virus R-HSA-5689877 Josephin domain DUBs 6/1313 12/10654 0.0016520380001715483 0.004218475634182904 0.002053865739871061 4287/7316/7415/6233/7311/7314 6 Norwalk_virus R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 6/1313 12/10654 0.0016520380001715483 0.004218475634182904 0.002053865739871061 834/835/843/7157/839/317 6 Norwalk_virus R-HSA-5627117 RHO GTPases Activate ROCKs 8/1313 20/10654 0.0016685302677459243 0.004251839963598957 0.0020701099614960786 1072/3984/4627/3985/9475/6093/387/5058 8 Norwalk_virus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 15/1313 54/10654 0.0017069294213955105 0.004340777483507845 0.0021134113198469006 8454/5684/5707/6500/7316/6790/5688/5686/5710/5704/6233/5716/7311/5693/7314 15 Norwalk_virus R-HSA-193639 p75NTR signals via NF-kB 7/1313 16/10654 0.0017677196303987053 0.004467902365223612 0.0021753051084764862 5584/7316/3654/6233/7311/3551/7314 7 Norwalk_virus R-HSA-205043 NRIF signals cell death from the nucleus 7/1313 16/10654 0.0017677196303987053 0.004467902365223612 0.0021753051084764862 23385/7316/6233/7311/5599/5663/7314 7 Norwalk_virus R-HSA-3229121 Glycogen storage diseases 7/1313 16/10654 0.0017677196303987053 0.004467902365223612 0.0021753051084764862 7316/378884/2632/2548/6233/7311/7314 7 Orf_virus R-HSA-449147 Signaling by Interleukins 266/1579 461/10654 1.169011764487396e-106 1.5208843055981022e-103 6.337274302221146e-104 5295/729230/8454/6095/3605/3557/7124/2308/54014/834/1052/10148/3725/7291/5777/596/9655/5601/351/1072/6464/2208/3592/5290/3566/1437/3667/4790/6885/6597/2309/5604/64109/3561/3587/5783/7412/6351/3578/7184/27250/27178/356/3593/3589/6775/207/50616/5292/5451/3684/9021/7422/29110/3553/2625/1230/1439/5594/3595/6624/4582/2919/6500/3082/5743/3091/941/1265/10538/4318/6367/3726/4312/3383/5705/58480/11009/6097/4478/6349/6657/1438/6778/53833/3576/4615/3581/3313/332/3662/3597/6776/5528/3688/2357/4313/7316/3565/4985/3934/6175/9978/2920/3560/3976/79155/6352/50615/6774/4314/1435/920/5970/1441/4792/4205/3055/5443/6850/1026/6348/9261/59307/3718/1440/3627/7133/3606/6772/8651/8809/4609/3146/6647/7867/9861/5566/149233/6364/5519/8503/7132/4988/5598/1901/3552/1432/4208/5701/867/79923/6950/3558/4067/3717/23291/4088/3636/2247/598/836/5698/5708/3320/5602/29949/4843/2335/2534/595/9466/5771/5710/3458/3181/6288/5702/2002/7157/6648/942/3654/7189/163702/112744/5609/5704/6233/2885/7525/58985/3716/85480/7409/1385/2353/604/282618/6196/7311/53832/3594/1154/6363/2939/1270/50604/9846/6347/3932/3575/4507/7076/302/1386/5296/7040/6935/3687/3588/51561/3570/8835/5599/5600/5784/7431/6777/7334/6356/3600/5008/3977/3312/3559/3929/3551/23765/246778/55801/6773/7850/7297/6416/5781/3569/3162/1489/5062/4170/3689/1234/5696/3601/3586/4791/5724/3554/4692/7314/3572/3596/5595/59067/3556 266 Orf_virus R-HSA-168273 Influenza Viral RNA Transcription and Replication 124/1579 134/10654 1.8485096711543055e-91 1.2024555410858758e-88 5.010434108655091e-89 6158/23165/6138/6144/2963/6203/5434/5440/5903/6227/9349/4736/6206/6194/6234/6191/55706/7175/6166/6128/51121/6132/9631/6159/6147/6129/6217/5430/6222/5436/6176/6152/6136/6125/6224/6146/348995/51065/6154/6141/6202/79023/6123/57122/5441/23636/6232/5438/6134/6169/10762/5431/6160/23511/6164/5435/6155/6175/5433/6218/53371/6209/6193/6173/23279/6210/4927/6231/6229/9688/11224/6205/6165/79902/6130/2962/6142/6167/6204/9883/6228/5437/23521/116832/23225/3320/6192/140801/6156/6235/6143/6181/5439/6124/6207/8086/6139/6233/7311/6223/25873/9972/3921/6188/6189/8021/6135/6201/129401/6161/9045/6187/5432/55746/6168/6208/6157/6137/6170/200916/8480/6122/6133/6230 124 Orf_virus R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 110/1579 112/10654 1.0397453071778792e-89 4.509028815461403e-87 1.8788380112161677e-87 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/1983/6176/6152/6136/8668/6125/8667/6224/6146/51065/6154/8662/6141/10480/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/6192/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 110 Orf_virus R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 109/1579 111/10654 7.324211710224887e-89 2.3821998587506446e-86 9.926234291488992e-87 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/6176/6152/6136/8668/6125/8667/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/6192/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 109 Orf_virus R-HSA-168254 Influenza Infection 133/1579 155/10654 4.514097376190124e-88 1.1745681372846702e-85 4.8942318920798174e-86 3839/6158/23165/6138/6144/2963/3837/3838/6203/5434/5440/5903/6227/9349/4736/6206/6194/6234/6191/55706/7175/6166/6128/51121/6132/9631/6159/6147/6129/6217/5430/6222/5436/6176/6152/6136/6125/6224/6146/348995/51065/6154/6141/9636/6202/79023/6123/57122/5441/23636/6232/5438/6134/6169/10762/5431/6160/23511/6164/5435/6155/6175/5433/6218/53371/6209/6193/6173/23279/6210/4927/6231/6229/9688/11224/6205/6165/79902/6130/2962/6142/3840/6167/6204/9883/6228/5437/23521/116832/23225/3320/6192/140801/6156/6235/6143/6181/5439/6124/6207/8086/3836/6139/6233/7514/7311/6223/25873/9972/5610/3921/6188/6189/8021/7040/6135/6201/129401/6161/9045/6187/5432/55746/6168/6208/6157/6137/6170/200916/8480/6122/6133/6230 133 Orf_virus R-HSA-168255 Influenza Life Cycle 127/1579 144/10654 2.4713960300964226e-87 5.358810391925743e-85 2.2329279921046626e-85 6158/23165/6138/6144/2963/3837/6203/5434/5440/5903/6227/9349/4736/6206/6194/6234/6191/55706/7175/6166/6128/51121/6132/9631/6159/6147/6129/6217/5430/6222/5436/6176/6152/6136/6125/6224/6146/348995/51065/6154/6141/6202/79023/6123/57122/5441/23636/6232/5438/6134/6169/10762/5431/6160/23511/6164/5435/6155/6175/5433/6218/53371/6209/6193/6173/23279/6210/4927/6231/6229/9688/11224/6205/6165/79902/6130/2962/6142/6167/6204/9883/6228/5437/23521/116832/23225/3320/6192/140801/6156/6235/6143/6181/5439/6124/6207/8086/3836/6139/6233/7514/7311/6223/25873/9972/3921/6188/6189/8021/6135/6201/129401/6161/9045/6187/5432/55746/6168/6208/6157/6137/6170/200916/8480/6122/6133/6230 127 Orf_virus R-HSA-72613 Eukaryotic Translation Initiation 112/1579 119/10654 8.655010005300596e-85 1.4075210021120094e-82 5.864908095697114e-83 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/1983/6176/6152/6136/8668/6125/8667/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/6192/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/1978/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 112 Orf_virus R-HSA-72737 Cap-dependent Translation Initiation 112/1579 119/10654 8.655010005300596e-85 1.4075210021120094e-82 5.864908095697114e-83 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/1983/6176/6152/6136/8668/6125/8667/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/6192/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/1978/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 112 Orf_virus R-HSA-72689 Formation of a pool of free 40S subunits 99/1579 101/10654 2.1136208603910274e-80 3.055356377076363e-78 1.2731166585981042e-78 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/6176/6152/6136/8668/6125/8667/6224/6146/51065/6154/8662/6141/10480/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/8663/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 99 Orf_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 99/1579 108/10654 5.748444949781117e-72 7.478726879665232e-70 3.1162622622497635e-70 5295/6095/3605/7124/2308/1052/7291/596/9655/2208/3592/3566/2309/3561/7412/7184/356/3593/207/5292/5451/3684/9021/7422/3553/2625/6624/4582/3082/5743/3091/10538/4318/6367/3726/4312/3383/58480/6097/6657/6778/3576/332/3662/3597/3688/4313/3565/4985/3934/3976/6774/4314/5443/1026/3718/7133/3606/6772/8651/4609/149233/4988/1901/3552/79923/3717/2247/598/3320/4843/2335/595/6288/7157/112744/3716/2353/604/6347/7076/7040/6935/3687/51561/3570/7431/6356/5008/3312/3929/7297/3569/3162/4170/3689/3586/4692/3596 99 Orf_virus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 91/1579 95/10654 6.460536967522418e-71 7.641053267951514e-69 3.1839009935636793e-69 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/6232/6134/6169/6160/6164/4686/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/1981/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/23708/6161/9045/5976/6187/6168/22916/6208/6157/6137/6170/200916/6122/6133/6230 91 Orf_virus R-HSA-156902 Peptide chain elongation 87/1579 89/10654 2.707320575800194e-70 2.935186724263377e-68 1.2230439443307893e-68 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/1938/6159/6147/6129/1915/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 87 Orf_virus R-HSA-5663205 Infectious disease 201/1579 383/10654 7.539093341825718e-70 7.544892644396354e-68 3.1438324461864333e-68 3839/6158/928/23165/5905/6138/6144/2963/3837/3838/2237/6917/6203/5434/5440/164/5903/6227/9349/4736/7852/6206/6194/6234/6191/55706/7175/6166/6128/51121/6132/9631/5604/1499/1938/3159/6159/6147/6129/6217/2959/5430/6874/6222/5436/6176/6152/6136/6125/4869/6500/404672/6749/6224/6146/348995/51065/6154/6141/9636/6202/79023/6123/57122/5705/5441/23636/6232/5438/6134/3978/3981/6169/10762/5431/6160/919/23511/6164/5435/4686/7316/6155/6175/9978/5433/6218/6872/2960/53371/920/4233/567/3055/926/6209/6193/6714/6173/23279/6210/4927/5605/6231/6229/9688/11224/6205/2966/6165/8731/9861/79902/6130/2962/6142/3840/6167/6204/9883/5701/867/6228/5437/23521/116832/23225/999/5698/5708/3320/2965/6192/2534/140801/6156/6235/6143/5710/2068/6181/5439/6124/5702/2071/6207/8086/3836/6139/5609/5704/6233/2885/3326/2968/7514/1025/7311/6223/25873/9972/2967/3932/5610/6908/3921/6188/6189/8021/7040/7251/11198/6135/6201/129401/6161/2547/9045/2961/6187/6416/5062/5432/55746/6168/22916/6208/1234/6157/6137/5696/6170/200916/8480/6122/6133/2957/7314/5879/25920/6230 201 Orf_virus R-HSA-156842 Eukaryotic Translation Elongation 89/1579 93/10654 2.9789443022843435e-69 2.768290383765665e-67 1.1535009892304037e-67 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/1917/1938/6159/6147/6129/1915/6217/1936/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 89 Orf_virus R-HSA-192823 Viral mRNA Translation 85/1579 89/10654 6.253590850818008e-66 5.423947797942819e-64 2.2600696759096663e-64 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 85 Orf_virus R-HSA-72764 Eukaryotic Translation Termination 87/1579 93/10654 2.8876375692621482e-65 2.3480102985062842e-63 9.783772027434251e-64 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/327/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/23708/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 87 Orf_virus R-HSA-2408557 Selenocysteine synthesis 85/1579 93/10654 1.4283596095561828e-61 1.0931152070779965e-59 4.554830953073895e-60 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 85 Orf_virus R-HSA-927802 Nonsense-Mediated Decay (NMD) 93/1579 115/10654 6.082660983831388e-57 4.165022073665598e-55 1.7354960701790387e-55 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/6232/26019/6134/6169/6160/6164/4686/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/1981/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/9775/6135/6201/23708/6161/9045/5976/6187/6168/22916/6208/6157/6137/6170/200916/6122/6133/6230 93 Orf_virus R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 93/1579 115/10654 6.082660983831388e-57 4.165022073665598e-55 1.7354960701790387e-55 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/6232/26019/6134/6169/6160/6164/4686/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/1981/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/9775/6135/6201/23708/6161/9045/5976/6187/6168/22916/6208/6157/6137/6170/200916/6122/6133/6230 93 Orf_virus R-HSA-2990846 SUMOylation 122/1579 188/10654 3.3213268838557024e-56 2.1605231379481344e-54 9.00254392202993e-55 1912/10054/6095/23165/7020/5905/286053/5903/7068/29843/55706/7175/1487/55143/5241/9631/5468/1029/8204/9112/8535/51564/1786/6045/9212/51588/3619/4869/3090/80012/7153/348995/79023/6613/57122/23636/2516/332/10762/5465/5885/23511/4929/28996/53371/1655/5970/4792/3190/6996/9759/9612/1911/6790/641/23137/6672/5111/2099/23279/4927/9688/79902/9656/9883/7341/1387/84733/10401/10521/1616/23225/2908/10055/59343/2033/23512/165918/8243/9126/57332/142/3066/3065/23314/7157/1107/1069/6256/8086/7329/5987/5371/7376/4152/672/10155/367/9972/6612/9063/25942/8021/6117/6294/129401/7703/11315/55746/8648/7421/6304/4791/8480/10891/10062/7508/6015/4193/8554/79677/205564 122 Orf_virus R-HSA-913531 Interferon Signaling 124/1579 199/10654 3.5560788755731037e-54 2.2030755319621942e-52 9.179852736441847e-53 3839/23165/3665/818/3460/5777/815/3837/3838/5903/10379/5335/55706/7175/115362/960/5770/9631/3455/7412/2316/817/2633/9021/54739/9830/4600/348995/9636/317649/79023/2537/3383/57122/23636/11274/8638/25820/1982/7706/2634/10762/3662/9470/23511/7316/3394/53371/3663/8519/3664/567/4734/3434/6672/6772/8651/23279/4927/9688/3659/3433/3106/79902/23586/8672/3840/3459/1958/25939/9883/4939/7341/3717/23225/1981/5771/1973/3458/3454/816/3661/8086/10346/7324/3836/9246/1977/5371/3439/51191/4599/6233/5580/3716/7311/9972/5610/5300/8021/9775/3127/4940/91543/3437/129401/7334/3456/6773/4938/7297/5781/4261/3430/55746/3105/5696/3660/5724/1974/8480/7314/5595/8554 124 Orf_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 117/1579 182/10654 2.9577140373710328e-53 1.749084528463506e-51 7.288147029885559e-52 1912/6095/23165/7020/5905/286053/5903/7068/55706/7175/1487/55143/5241/9631/5468/1029/8204/9112/8535/51564/1786/6045/9212/51588/3619/4869/3090/80012/7153/348995/79023/6613/57122/23636/2516/332/10762/5465/5885/23511/4929/28996/53371/1655/5970/4792/3190/6996/9759/9612/1911/6790/641/23137/6672/5111/2099/23279/4927/9688/79902/9656/9883/7341/1387/84733/10401/10521/1616/23225/2908/2033/23512/165918/8243/9126/57332/142/3066/3065/23314/7157/1107/1069/6256/8086/7329/5987/5371/7376/4152/672/10155/367/9972/6612/9063/25942/8021/6117/6294/129401/7703/11315/55746/8648/7421/6304/4791/8480/10891/10062/7508/6015/4193/8554/79677 117 Orf_virus R-HSA-1257604 PIP3 activates AKT signaling 144/1579 264/10654 1.441778837188881e-52 8.155453335577106e-51 3.398243025868529e-51 5295/1912/2308/27161/3725/6591/8841/5290/3667/2309/5468/1822/23186/842/3815/389541/2146/5978/9112/9219/8535/10273/207/51564/6045/57690/5594/4303/84335/84232/1027/7249/27327/80012/930/3082/5931/58528/1460/941/2064/5705/6199/192670/2260/4615/153129/5528/2100/7316/1950/2263/1457/4233/1026/1911/4734/6714/2099/1108/57167/2122/9861/7101/64223/10014/5519/8503/1958/5928/2932/2261/5701/84733/10325/5159/57459/2247/8649/3164/5698/5708/5880/54815/2534/23512/57332/5728/6009/5710/6615/3630/5702/192669/3066/3065/7157/1107/23028/8975/942/5987/3654/7189/5371/23112/10542/5704/6233/2885/79109/2475/55004/7409/1385/57504/7311/3932/2931/5155/1386/10670/1956/4254/5296/4343/8726/23466/26523/7874/5781/64121/53615/57521/5696/5156/7314/5879/6015/253260/28956/5595/4193/3556 144 Orf_virus R-HSA-9006925 Intracellular signaling by second messengers 156/1579 305/10654 5.27944918793583e-52 2.8619014139602147e-50 1.192507163064453e-50 5295/1912/2308/818/27161/3725/6591/815/3838/8841/5290/3667/5335/2309/5468/1822/23186/842/3815/5567/389541/2146/5978/9112/9219/8535/817/10273/207/51564/6045/57690/5594/4303/84335/5568/84232/1027/7249/27327/80012/930/3082/5931/58528/1460/941/2064/5705/6199/192670/2260/4615/153129/5528/2100/7316/1950/2263/1457/4233/1026/1911/4734/6714/2099/1108/57167/2122/9861/7101/64223/5566/10014/5519/8503/1958/5928/2932/2261/5701/84733/10325/5159/57459/5576/2247/8649/3164/5698/5708/5880/54815/2534/23512/57332/5728/6009/5710/6615/816/3630/5702/192669/3066/3065/7157/1107/23028/8975/942/5987/3654/7189/5371/23112/10542/5704/6233/2885/79109/5580/2475/55004/7409/1385/57504/7311/3932/2931/5155/1386/10670/1956/4254/5296/5581/4343/8726/23466/26523/7874/5781/64121/53615/57521/5696/5156/7314/5879/6015/253260/28956/5595/4193/3556 156 Orf_virus R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 85/1579 112/10654 5.154636847726744e-48 2.6824730155569975e-46 1.117742305928115e-46 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 85 Orf_virus R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 58/1579 59/10654 1.668977494214797e-47 8.351306615282504e-46 3.4798518604073705e-46 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/8668/8667/6224/51065/8662/10480/26986/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/6192/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/8665/6201/1978/6187/6208/1974/1968/6230 58 Orf_virus R-HSA-3700989 Transcriptional Regulation by TP53 167/1579 365/10654 3.99966299511574e-47 1.9272450209798436e-45 8.030512446333746e-46 1017/834/6118/2176/27161/3725/2963/6917/9134/5434/5440/4436/9156/7531/1029/389541/5430/9219/6874/207/5436/22974/9212/57690/835/7832/4849/1027/4869/5982/7249/404672/27327/5931/58528/4850/1460/6749/11200/545/472/5441/192670/332/5438/153129/5431/11073/9337/639/5435/7316/5433/1869/891/6872/28996/890/84289/1457/54971/983/1026/54205/6790/641/5111/25904/1108/1643/2966/246175/64223/4194/2962/9656/5519/6119/1647/5928/3364/1432/10524/1387/4848/10325/5437/57459/23019/1616/9099/843/2821/8649/2177/2965/5985/54815/2033/995/10128/84126/5728/6009/2068/5439/1111/192669/3066/3065/2071/7157/1107/55215/8900/5984/5371/23112/10498/10542/6233/79109/2968/2475/55004/672/55571/1025/2353/604/7311/7161/839/2967/1386/10670/6908/4513/8851/5300/5983/4343/6117/11198/50484/5600/57472/3276/85456/29883/26523/7874/1020/5884/5810/64121/53615/8795/5432/57521/26013/7529/7314/253260/28956/4193/25920 167 Orf_virus R-HSA-72649 Translation initiation complex formation 57/1579 58/10654 1.1422884679635763e-46 5.124542402829699e-45 2.135312381129734e-45 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/8668/8667/6224/51065/8662/10480/26986/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/6192/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1974/1968/6230 57 Orf_virus R-HSA-72702 Ribosomal scanning and start codon recognition 57/1579 58/10654 1.1422884679635763e-46 5.124542402829699e-45 2.135312381129734e-45 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/1983/8668/8667/6224/51065/8662/10480/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/6192/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1974/1968/6230 57 Orf_virus R-HSA-376176 Signaling by ROBO receptors 121/1579 218/10654 2.8805686539183665e-45 1.249206606249265e-43 5.205238093922662e-44 6158/6138/6144/25/6203/6227/9349/4736/7852/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/5567/6222/6176/6152/6136/5532/5568/6125/27/6224/6146/51065/6154/6141/26986/6202/6123/5705/6232/26019/6134/6169/6160/6164/4686/7316/6155/6175/9978/6218/6209/6193/6714/6173/6210/6231/6229/11224/6205/6165/9861/5566/6130/6142/6167/6204/5701/6228/23521/116832/5576/10486/5698/5708/6192/1981/140801/6156/6235/6143/5710/6181/6124/5702/6207/6139/10487/5704/6233/23380/7311/6223/25873/387/1630/3921/6188/6189/9775/6135/6201/23708/6161/9045/6187/5062/6168/22916/6208/6157/6137/5696/6170/200916/6122/6133/7314/5879/6387/6230 121 Orf_virus R-HSA-2408522 Selenoamino acid metabolism 85/1579 118/10654 6.204188763642367e-45 2.603757929515716e-43 1.0849430265792254e-43 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 85 Orf_virus R-HSA-8943724 Regulation of PTEN gene transcription 58/1579 61/10654 7.510069040931237e-45 3.053312444453606e-43 1.2722649855524955e-43 1912/3725/6591/8841/5468/1822/23186/389541/2146/5978/9112/9219/8535/51564/6045/5594/84232/80012/5931/58528/153129/1911/1108/57167/2122/7101/64223/10014/1958/5928/84733/10325/57459/8649/54815/23512/57332/6009/6615/3066/3065/7157/1107/23028/10542/2475/55004/57504/1386/10670/8726/23466/64121/53615/57521/6015/28956/5595 58 Orf_virus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 104/1579 171/10654 4.495698014922645e-44 1.772394884064958e-42 7.385277440782018e-43 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/5705/6232/26019/6134/6169/6160/6164/4686/7316/6155/6175/9978/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/9861/6130/6142/6167/6204/5701/6228/23521/116832/5698/5708/6192/1981/140801/6156/6235/6143/5710/6181/6124/5702/6207/6139/5704/6233/7311/6223/25873/3921/6188/6189/9775/6135/6201/23708/6161/9045/6187/6168/22916/6208/6157/6137/5696/6170/200916/6122/6133/7314/6230 104 Orf_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 67/1579 80/10654 3.661699012215889e-43 1.4011383573214326e-41 5.83831266653617e-42 3839/23165/3837/3838/5903/5335/55706/7175/9631/2316/4600/348995/9636/317649/79023/57122/23636/11274/8638/25820/1982/7706/10762/9470/23511/7316/53371/4734/3434/6772/23279/4927/9688/79902/23586/8672/3840/9883/4939/23225/1981/1973/3661/8086/7324/3836/9246/1977/51191/4599/6233/3716/7311/9972/5610/5300/8021/9775/4940/129401/7334/4938/55746/1974/8480/7314/5595 67 Orf_virus R-HSA-2262752 Cellular responses to stress 190/1579 479/10654 2.0673868048916788e-42 7.684772094754497e-41 3.2021179083284645e-41 1912/1017/23165/818/6118/3725/84617/815/9134/1019/5903/5601/11065/573/4790/55706/7175/5241/9631/3159/112399/7531/7290/1029/1915/389541/2146/8535/51807/817/6045/7422/10382/57690/5594/84335/23677/1027/27327/80012/5931/58528/5925/3091/7277/348995/1051/10013/545/79023/472/10381/57122/5705/23636/192670/3576/7278/3313/153129/112714/1780/10762/3490/8881/29855/23511/7316/9978/2114/1869/890/53371/6774/5970/1026/1639/9261/1911/54205/6667/2289/23279/4927/9688/7415/1871/6647/7867/8994/9861/79902/64223/4194/6119/5598/9883/3552/5928/1432/2932/5701/10524/1387/84733/10325/7846/23225/113457/2908/8649/5698/347733/5708/3320/5602/2033/23512/57332/10376/6009/5710/6767/25842/816/5702/192669/10540/7157/8900/6648/8086/23135/7324/10963/22824/23112/5609/10542/5704/6233/2056/3326/2475/55004/2353/6196/7311/367/9972/538/2034/10383/10670/23411/84790/8021/4343/8726/55662/6117/5599/129401/5600/3312/23466/4217/26523/3456/528/2113/405/6416/3569/64121/3297/57521/55746/5696/7280/2288/8480/768/10728/7314/6015/28956/5595/4193/2950 190 Orf_virus R-HSA-1169408 ISG15 antiviral mechanism 62/1579 72/10654 1.634973760520073e-41 5.9086135067683744e-40 2.4620218908416306e-40 3839/23165/3837/3838/5903/5335/55706/7175/9631/4600/348995/9636/317649/79023/57122/23636/11274/25820/1982/7706/10762/9470/23511/7316/53371/4734/3434/6772/23279/4927/9688/79902/23586/8672/3840/9883/23225/1981/1973/3661/8086/7324/3836/9246/1977/51191/4599/6233/3716/7311/9972/5610/5300/8021/9775/129401/7334/55746/1974/8480/7314/5595 62 Orf_virus R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 50/1579 51/10654 7.840761351322806e-41 2.7569812211002625e-39 1.1487886474911082e-39 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/8668/8667/6224/51065/8662/10480/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/6204/8663/6228/8894/6192/6235/6207/6233/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1968/6230 50 Orf_virus R-HSA-5663202 Diseases of signal transduction 161/1579 377/10654 1.1440119140537364e-40 3.9167355267997657e-39 1.6320391571680727e-39 5295/8454/4000/2308/818/2963/815/8805/5434/5440/7276/11052/6464/26127/8841/5290/3667/5335/1487/2309/5604/1499/10018/9734/842/3815/5430/8844/23462/817/207/51564/5436/1452/55534/5594/3280/4303/84335/613/1027/7249/6500/409/930/3082/84441/941/10533/10013/2064/5705/5441/6199/10046/2260/5438/9208/5431/6776/5528/2100/5435/4686/7316/9978/5433/1950/9611/6774/2263/4233/9759/9612/1026/6772/6714/2099/6934/5605/4609/7415/9861/64223/4089/10014/2962/5519/8850/8503/399687/2932/2261/5701/867/1387/5437/5159/3717/4088/2247/3164/5698/5708/5880/3320/2335/2534/2033/408/55294/5728/1445/5710/5439/816/5702/3066/3065/4087/942/9794/5704/6233/2885/79109/2475/7409/1385/7048/7311/9846/3932/2931/5155/1956/60/4254/5296/7040/3845/388585/6777/3265/3516/4763/5781/4851/5432/22916/5696/7750/5245/7529/5156/7314/1523/5879/253260/5595/4193 161 Orf_virus R-HSA-8953897 Cellular responses to external stimuli 190/1579 493/10654 2.7568847195384288e-40 9.196684666973066e-39 3.832106965080407e-39 1912/1017/23165/818/6118/3725/84617/815/9134/1019/5903/5601/11065/573/4790/55706/7175/5241/9631/3159/112399/7531/7290/1029/1915/389541/2146/8535/51807/817/6045/7422/10382/57690/5594/84335/23677/1027/27327/80012/5931/58528/5925/3091/7277/348995/1051/10013/545/79023/472/10381/57122/5705/23636/192670/3576/7278/3313/153129/112714/1780/10762/3490/8881/29855/23511/7316/9978/2114/1869/890/53371/6774/5970/1026/1639/9261/1911/54205/6667/2289/23279/4927/9688/7415/1871/6647/7867/8994/9861/79902/64223/4194/6119/5598/9883/3552/5928/1432/2932/5701/10524/1387/84733/10325/7846/23225/113457/2908/8649/5698/347733/5708/3320/5602/2033/23512/57332/10376/6009/5710/6767/25842/816/5702/192669/10540/7157/8900/6648/8086/23135/7324/10963/22824/23112/5609/10542/5704/6233/2056/3326/2475/55004/2353/6196/7311/367/9972/538/2034/10383/10670/23411/84790/8021/4343/8726/55662/6117/5599/129401/5600/3312/23466/4217/26523/3456/528/2113/405/6416/3569/64121/3297/57521/55746/5696/7280/2288/8480/768/10728/7314/6015/28956/5595/4193/2950 190 Orf_virus R-HSA-6807070 PTEN Regulation 89/1579 140/10654 4.5411025633985115e-40 1.4769936087453658e-38 6.154389000395351e-39 1912/27161/3725/6591/8841/5468/1822/23186/389541/2146/5978/9112/9219/8535/10273/207/51564/6045/57690/5594/84232/27327/80012/5931/58528/1460/5705/192670/153129/7316/1457/1911/4734/1108/57167/2122/9861/7101/64223/10014/1958/5928/5701/84733/10325/57459/8649/5698/5708/54815/23512/57332/5728/6009/5710/6615/5702/192669/3066/3065/7157/1107/23028/8975/5987/5371/23112/10542/5704/6233/2475/55004/57504/7311/1386/10670/4343/8726/23466/26523/7874/64121/53615/57521/5696/7314/6015/28956/5595 89 Orf_virus R-HSA-6783783 Interleukin-10 signaling 45/1579 47/10654 2.269884151652801e-35 7.2027299543909615e-34 3.001258891145552e-34 729230/3557/7124/2208/3592/1437/3587/6351/3593/3553/1230/2919/5743/941/6367/3383/6349/3576/2357/2920/3976/6352/6774/1435/6348/1440/3627/7133/3606/6364/7132/3552/942/3716/6363/6347/7076/3588/7850/7297/3569/1234/3586/5724/3554 45 Orf_virus R-HSA-5696398 Nucleotide Excision Repair 73/1579 111/10654 1.6755395326490379e-34 5.190183171372377e-33 2.162663807805149e-33 9318/6118/6917/5434/5440/5430/83444/5436/5982/404672/54107/9557/6613/5441/7507/7336/5438/3978/5431/8450/5435/54778/7316/9978/5433/5425/5111/5426/1643/2966/10980/6119/7341/5437/10401/5427/1642/2965/5985/2033/142/2068/5439/10987/2071/5984/1069/7329/6233/51426/2968/7311/2967/6612/3980/60/5887/5983/6117/2073/7334/5981/10038/7874/5424/5432/5886/7508/7314/8451/8554/7528/56655 73 Orf_virus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 59/1579 77/10654 4.999390568266181e-34 1.5126063091428607e-32 6.3027812549745e-33 1912/23165/286053/5903/55706/7175/9631/1029/8535/51564/6045/51588/80012/348995/79023/6613/57122/23636/10762/5885/23511/53371/6996/1911/641/23137/6672/23279/4927/9688/79902/9656/9883/7341/84733/23225/165918/8243/9126/57332/142/1069/8086/7329/5371/672/9972/6612/9063/8021/6117/129401/7703/55746/8480/7508/6015/8554/79677 59 Orf_virus R-HSA-69242 S Phase 85/1579 161/10654 6.981149069141439e-30 2.064198849762048e-28 8.601176484707753e-29 8454/1017/4172/6118/2237/9134/1019/994/5000/11065/8318/23594/207/9837/64785/1027/5982/6500/54107/5925/23244/4173/5705/4149/3978/8881/5885/5557/7316/5422/9978/1869/4174/5753/993/890/1026/5425/84515/5111/5426/4171/4609/9861/4998/6119/5928/2932/5701/5427/6502/5698/5708/5985/990/8243/9126/595/4175/5710/81620/5702/8900/5984/7324/5704/6233/23595/7311/84296/51659/23649/157570/5983/6117/5001/5981/7465/5558/5424/5696/4999/4176/7314/56655 85 Orf_virus R-HSA-453279 Mitotic G1-G1/S phases 81/1579 149/10654 1.0616909685967217e-29 3.0694665558763e-28 1.2789961376077465e-28 8454/1017/4172/6118/25/9134/1019/5000/8318/23594/1029/8317/207/1027/6500/7153/54107/5925/4173/5705/4149/5557/7316/5422/1869/4174/891/5753/993/890/983/1026/84515/5111/5426/6714/4171/4609/1871/9861/51053/5519/4998/6119/5928/5701/10926/5427/4067/3717/6502/5698/5708/990/595/4175/5710/81620/5702/3065/8900/5704/6233/7298/55388/29935/23595/7311/23649/6117/1719/5001/7465/5558/5696/4999/7083/4176/7314/6241/56655 81 Orf_virus R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 92/1579 185/10654 1.2433136567650675e-29 3.51641536402468e-28 1.46523234149659e-28 6158/6138/6144/6203/6227/9349/4736/6206/6194/57418/6234/6191/6166/6128/51121/6132/6159/6147/25879/6129/6217/6222/6176/6152/6136/27043/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/26168/3921/6188/6189/26354/6135/6201/6161/9045/6187/4691/6168/6208/6157/6137/6170/200916/6122/6133/9188/6230 92 Orf_virus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 58/1579 84/10654 2.200936586010269e-29 6.092379783828426e-28 2.53859427053816e-28 9318/6118/83444/5982/404672/54107/9557/6613/7507/7336/3978/8450/54778/7316/9978/5425/5111/5426/1643/2966/10980/6119/7341/10401/5427/1642/2965/5985/142/2068/10987/2071/5984/1069/7329/6233/51426/2968/7311/2967/6612/3980/60/5887/5983/6117/2073/7334/5981/10038/5424/5886/7508/7314/8451/8554/7528/56655 58 Orf_virus R-HSA-8939211 ESR-mediated signaling 102/1579 223/10654 6.573432477998731e-29 1.7816740945575727e-27 7.423942381950321e-28 5295/2788/3727/27161/3725/2354/2963/3838/596/5434/5440/5590/6464/5290/54331/5241/4316/2309/5747/8204/5430/2770/207/5436/5451/2625/57690/5594/1027/3315/27327/4318/5441/192670/5438/5431/5885/2100/5435/4313/5433/1950/865/5469/1655/4314/6667/2289/6714/2099/4609/2962/8850/8503/10524/1387/5437/3320/2033/8243/4846/9126/595/2783/2782/5439/192669/3065/2002/861/23028/2786/23112/2771/10498/3326/7514/1385/1025/2353/1386/6908/1956/3169/5296/4343/3845/3276/3265/26523/8202/5432/8648/3480/2288/2773/10728/2957/5595/2787/7528/6387 102 Orf_virus R-HSA-69206 G1/S Transition 74/1579 131/10654 1.1218928682060346e-28 2.9259424102617884e-27 1.2191919910067728e-27 8454/1017/4172/6118/9134/1019/5000/8318/23594/8317/207/1027/6500/54107/5925/4173/5705/4149/5557/7316/5422/1869/4174/891/5753/993/890/983/1026/84515/5111/5426/4171/4609/9861/51053/5519/4998/6119/5928/5701/10926/5427/6502/5698/5708/990/595/4175/5710/81620/5702/3065/8900/5704/6233/7298/55388/29935/23595/7311/23649/6117/1719/5001/7465/5558/5696/4999/7083/4176/7314/6241/56655 74 Orf_virus R-HSA-72766 Translation 120/1579 291/10654 1.1244974674334314e-28 2.9259424102617884e-27 1.2191919910067728e-27 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/327/6166/6128/51121/6132/1917/1938/6159/6147/8666/6129/1915/6217/1936/6222/1983/6176/6152/6136/8668/6125/8667/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/9669/10240/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/6192/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/1978/23708/6161/9045/6187/6168/6208/6157/6137/6170/7284/1974/200916/6122/6133/1968/6230 120 Orf_virus R-HSA-68962 Activation of the pre-replicative complex 33/1579 33/10654 3.2659273570437583e-28 8.331316650027314e-27 3.471522371264263e-27 1017/4172/6118/5000/8318/23594/8317/54107/4173/5557/5422/4174/84515/5426/4171/51053/4998/6119/10926/5427/990/4175/81620/55388/29935/23595/23649/6117/5001/5558/4999/4176/56655 33 Orf_virus R-HSA-69306 DNA Replication 72/1579 127/10654 4.5681705798251685e-28 1.1429211392985663e-26 4.762364066012068e-27 8454/1017/4172/6118/2237/9134/5000/11065/8318/23594/8317/9837/64785/5982/6500/54107/4173/5705/3978/8881/5557/7316/5422/9978/1869/4174/890/5425/84515/5111/5426/4171/1871/9861/51053/4998/6119/5701/10926/5427/6502/5698/5708/5985/990/4175/5710/81620/5702/8900/5984/7324/5704/6233/55388/29935/23595/7311/84296/51659/23649/5983/6117/5001/5981/5558/5424/5696/4999/4176/7314/56655 72 Orf_virus R-HSA-8868773 rRNA processing in the nucleus and cytosol 92/1579 195/10654 2.0150308566356597e-27 4.946330461288666e-26 2.0610544015240608e-26 6158/6138/6144/6203/6227/9349/4736/6206/6194/57418/6234/6191/6166/6128/51121/6132/6159/6147/25879/6129/6217/6222/6176/6152/6136/27043/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/26168/3921/6188/6189/26354/6135/6201/6161/9045/6187/4691/6168/6208/6157/6137/6170/200916/6122/6133/9188/6230 92 Orf_virus R-HSA-3371556 Cellular response to heat stress 58/1579 89/10654 2.510628583836405e-27 6.04875516216882e-26 2.5204166095043833e-26 23165/818/6118/815/5903/573/55706/7175/9631/7531/1915/817/5594/84335/348995/10013/545/79023/472/57122/23636/3313/10762/23511/53371/9261/23279/4927/9688/7415/79902/64223/6119/9883/2932/1387/23225/3320/2033/6767/816/8086/22824/3326/2475/9972/23411/8021/6117/129401/3312/3297/57521/55746/2288/8480/10728/5595 58 Orf_virus R-HSA-176187 Activation of ATR in response to replication stress 35/1579 37/10654 3.395882976267829e-27 8.032806822044447e-26 3.347138244551066e-26 1017/4172/6118/5000/8318/23594/8317/5982/63967/4173/545/4174/993/84515/4171/4998/6119/3364/10926/5985/990/995/84126/4175/1111/5984/55388/23595/5983/6117/5001/5884/5810/4999/4176 35 Orf_virus R-HSA-73894 DNA Repair 128/1579 334/10654 6.745314896161375e-27 1.567081192840348e-25 6.529769119404339e-26 9318/1017/6118/2176/54962/25/3838/2237/6917/5434/5440/2178/4436/151987/5888/9156/328/5430/83444/5436/51588/2956/5982/63967/404672/54107/9557/5531/9636/11200/545/472/6613/5441/7507/7706/7336/51567/5438/3978/3981/5431/11073/5591/8450/5435/54778/7316/9978/5433/890/6996/5425/641/5111/5426/1643/2966/7415/10980/9656/6119/84464/83932/3364/22976/7341/10524/5437/10401/5427/2177/1642/2965/5985/2033/165918/84126/142/8914/2068/5439/1111/10987/2071/7157/55215/8900/5984/1069/7329/9246/6233/51426/2968/672/7311/6047/9025/2967/6612/3980/60/5887/5983/6117/2073/5599/7334/5981/10038/7874/2547/5884/5810/5424/5432/348654/5886/55183/7508/7314/51514/7374/8451/8554/7528/56655 128 Orf_virus R-HSA-5696400 Dual Incision in GG-NER 37/1579 41/10654 8.041962891715843e-27 1.835542758267072e-25 7.648404227578318e-26 6118/5982/404672/54107/9557/7507/8450/7316/9978/5425/5111/5426/1643/2966/6119/5427/1642/2965/5985/142/2068/2071/5984/6233/51426/2968/7311/2967/5983/6117/2073/5981/10038/5424/7314/8451/56655 37 Orf_virus R-HSA-168325 Viral Messenger RNA Synthesis 38/1579 43/10654 9.531131528011733e-27 2.1379313996453904e-25 8.908407871009151e-26 23165/2963/5434/5440/5903/55706/7175/9631/5430/5436/348995/79023/57122/5441/23636/5438/10762/5431/23511/5435/5433/53371/23279/4927/9688/79902/2962/9883/5437/23225/5439/8086/9972/8021/129401/5432/55746/8480 38 Orf_virus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 48/1579 65/10654 1.2020237225542658e-26 2.6505641746493215e-25 1.1044464176903601e-25 6118/6917/5434/5440/5430/5436/5982/404672/54107/5441/5438/3978/5431/8450/5435/7316/9978/5433/5425/5111/5426/2966/6119/5437/5427/1642/2965/5985/2033/2068/5439/2071/5984/6233/51426/2968/7311/2967/3980/5983/6117/5981/7874/5424/5432/7314/8451/56655 48 Orf_virus R-HSA-6782135 Dual incision in TC-NER 48/1579 66/10654 3.7839753955695147e-26 8.204919982726565e-25 3.418854962663684e-25 6118/6917/5434/5440/5430/5436/5982/404672/54107/5441/7507/5438/5431/8450/5435/7316/9978/5433/5425/5111/5426/2966/6119/5437/5427/1642/2965/5985/2033/2068/5439/2071/5984/6233/51426/2968/7311/2967/5983/6117/2073/5981/7874/5424/5432/7314/8451/56655 48 Orf_virus R-HSA-72312 rRNA processing 93/1579 205/10654 4.147371764196163e-26 8.845460106916734e-25 3.685757478103579e-25 6158/6138/6144/6203/6227/9349/4736/6206/6194/57418/6234/6191/6166/6128/51121/6132/6159/6147/25879/6129/6217/3028/6222/6176/6152/6136/27043/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/26168/3921/6188/6189/26354/6135/6201/6161/9045/6187/4691/6168/6208/6157/6137/6170/200916/6122/6133/9188/6230 93 Orf_virus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 53/1579 79/10654 5.290443918956817e-26 1.1101399255746484e-24 4.625770149851886e-25 9318/6118/6917/5434/5440/5430/5436/5982/404672/54107/5441/7507/5438/3978/5431/8450/5435/7316/9978/5433/5425/5111/5426/2966/10980/6119/5437/5427/1642/2965/5985/2033/2068/5439/10987/2071/5984/6233/51426/2968/7311/2967/3980/5983/6117/2073/5981/7874/5424/5432/7314/8451/56655 53 Orf_virus R-HSA-4615885 SUMOylation of DNA replication proteins 38/1579 45/10654 3.3122293512938112e-25 6.84001648576706e-24 2.8501221652737054e-24 23165/5905/5903/55706/7175/55143/9631/9212/51588/3619/7153/348995/79023/6613/57122/23636/332/10762/23511/53371/6790/5111/23279/4927/9688/79902/9883/7341/10401/23225/8086/7329/9972/6612/8021/129401/55746/8480 38 Orf_virus R-HSA-5696395 Formation of Incision Complex in GG-NER 37/1579 43/10654 3.568939663616486e-25 7.254985159945388e-24 3.0230327742804118e-24 6118/404672/9557/6613/7507/7336/8450/54778/7316/9978/1643/2966/6119/7341/10401/1642/2965/142/2068/2071/1069/7329/6233/2968/7311/2967/6612/5887/6117/2073/7334/10038/5886/7508/7314/8451/8554 37 Orf_virus R-HSA-162587 HIV Life Cycle 76/1579 152/10654 7.4592165927351655e-25 1.492990890330531e-23 6.221047036856048e-24 23165/5905/2963/2237/6917/5434/5440/5903/7852/55706/7175/9631/3159/2959/5430/6874/5436/404672/6749/348995/79023/57122/5441/23636/5438/3978/3981/10762/5431/23511/5435/4686/7316/5433/6872/2960/53371/920/23279/4927/9688/2966/8731/79902/2962/9883/5437/23225/2965/2068/5439/2071/8086/3836/6233/2968/7514/1025/7311/9972/2967/6908/8021/7251/11198/129401/2547/2961/5432/55746/22916/1234/8480/2957/7314/25920 76 Orf_virus R-HSA-162906 HIV Infection 98/1579 233/10654 2.3585904983981312e-24 4.649282179418134e-23 1.9372792769936803e-23 23165/5905/2963/3837/2237/6917/5434/5440/164/5903/7852/55706/7175/9631/3159/2959/5430/6874/5436/4869/6500/404672/6749/348995/79023/57122/5705/5441/23636/5438/3978/3981/10762/5431/919/23511/5435/4686/7316/9978/5433/6872/2960/53371/920/567/3055/926/23279/4927/9688/2966/8731/9861/79902/2962/9883/5701/5437/23225/5698/5708/2965/2534/5710/2068/5439/5702/2071/8086/3836/5704/6233/2968/7514/1025/7311/9972/2967/3932/6908/8021/7251/11198/129401/2547/2961/5062/5432/55746/22916/1234/5696/8480/2957/7314/5879/25920 98 Orf_virus R-HSA-69239 Synthesis of DNA 65/1579 119/10654 3.2620505510829554e-24 6.334220547699888e-23 2.639365331983852e-23 8454/1017/4172/6118/2237/9134/5000/11065/8318/23594/9837/64785/5982/6500/54107/4173/5705/3978/8881/5557/7316/5422/9978/4174/890/5425/84515/5111/5426/4171/9861/4998/6119/5701/5427/6502/5698/5708/5985/990/4175/5710/81620/5702/8900/5984/7324/5704/6233/23595/7311/84296/51659/23649/5983/6117/5001/5981/5558/5424/5696/4999/4176/7314/56655 65 Orf_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 155/1579 473/10654 6.541187359198438e-24 1.2514830521054658e-022 5.214723668710829e-23 5295/54106/26999/4908/5777/627/2963/10253/5434/5440/5590/6464/5290/2670/3667/5335/5241/5770/4915/5604/1499/5747/3815/5567/5430/10273/207/5436/7422/5594/5568/2322/7074/3315/3082/3178/4318/2064/5441/58513/6778/2260/5438/348/5431/6776/5528/9306/5435/3688/4686/7316/5433/1950/5753/9611/9047/6774/2263/4205/4233/9261/4734/10413/6772/6714/2099/8651/5605/7867/64223/5566/8569/2962/5519/8503/5598/1432/2261/4208/867/5437/5159/4670/4067/3717/4909/2247/4914/3320/2335/2534/4846/4803/5771/1445/5439/1111/5603/3630/2002/83737/3913/3925/6233/2885/7525/3187/79109/5580/2475/7409/23191/1385/3685/6196/7311/9846/3932/3479/5155/3791/387/1956/60/4254/8851/5296/5581/3845/5600/6777/3265/6300/528/1020/5781/5062/5432/3480/22916/10603/10252/5725/4916/7529/5156/10787/7314/5879/253260/5595/25920/6387/2242 155 Orf_virus R-HSA-9006931 Signaling by Nuclear Receptors 112/1579 299/10654 1.1168711521078856e-22 2.1058686505686365e-21 8.774807678650817e-22 5295/2788/3727/27161/3725/2354/2963/3838/596/5434/5440/5590/6464/8841/5290/54331/1374/5241/4316/2309/5747/8204/5430/2770/207/5436/5451/2625/57690/5594/1027/3315/27327/4318/5441/192670/5438/348/5431/5885/2100/5435/4313/5433/1950/9611/865/5469/1655/4314/9612/6667/2289/6714/2099/4609/2962/8850/8503/10524/1387/5437/5467/3320/2033/8243/4846/9126/595/2783/2782/5439/192669/3065/2002/861/23028/6256/2786/23112/2771/7376/10498/3326/7514/1385/1025/2353/1738/1386/6908/1956/3169/5296/4343/3845/3276/3265/26523/8202/5432/8648/3480/2288/2773/10728/2957/10062/5595/2787/7528/6387 112 Orf_virus R-HSA-4570464 SUMOylation of RNA binding proteins 37/1579 47/10654 1.6474612552559627e-22 3.0619244186971535e-21 1.2758534533185275e-21 1912/23165/5903/55706/7175/9631/8535/6045/80012/348995/79023/6613/57122/23636/10762/23511/53371/3190/1911/23279/4927/9688/79902/9883/7341/84733/23225/57332/8086/7329/9972/8021/129401/7703/55746/8480/6015 37 Orf_virus R-HSA-4551638 SUMOylation of chromatin organization proteins 46/1579 71/10654 9.062457225032654e-22 1.6605995563052795e-20 6.919444730751395e-21 1912/23165/5903/55706/7175/9631/8535/6045/80012/348995/79023/6613/57122/23636/10762/23511/53371/9759/1911/23279/4927/9688/79902/9883/7341/84733/23225/23512/57332/3066/3065/23314/1107/8086/7329/9972/6612/9063/8021/129401/7703/55746/6304/8480/6015/8554 46 Orf_virus R-HSA-5633007 Regulation of TP53 Activity 74/1579 160/10654 1.2751949961844313e-21 2.3042065139388125e-20 9.60124887478044e-21 1017/6118/9156/1029/9219/6874/207/22974/9212/5982/5931/1460/6749/11200/545/472/11073/639/7316/6872/28996/890/84289/1457/54971/983/6790/641/1108/64223/4194/5519/6119/5928/3364/1432/10524/57459/1616/9099/5985/54815/2033/84126/1111/3066/3065/7157/1107/8900/5984/5371/6233/79109/2475/672/7311/7161/6908/8851/5300/5983/6117/11198/5600/7874/1020/5884/5810/53615/26013/7314/253260/4193 74 Orf_virus R-HSA-69190 DNA strand elongation 29/1579 32/10654 2.2744891162683298e-21 4.053575808582325e-20 1.689058247841658e-20 4172/6118/2237/8318/9837/64785/5982/4173/3978/5557/5422/4174/5425/84515/5111/4171/6119/5985/4175/5984/84296/51659/23649/5983/6117/5981/5558/5424/4176 29 Orf_virus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 32/1579 38/10654 2.4835524775673144e-21 4.3663537477230756e-20 1.8193876613757706e-20 23165/5903/55706/7175/9631/51588/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/7341/23225/8086/7329/5987/5371/9972/9063/8021/129401/55746/8480/4193/8554 32 Orf_virus R-HSA-69620 Cell Cycle Checkpoints 108/1579 293/10654 2.8872863655929302e-21 5.0084794155152035e-20 2.086950846709276e-20 1017/4172/6118/5905/11130/9134/5903/10403/5000/11065/8318/55143/9156/23594/7531/1029/1058/991/79019/8317/9212/51588/1027/3619/5982/63967/348995/4173/11200/545/79023/9133/472/57122/5705/7336/6232/332/1780/8881/11073/5528/7316/4174/891/993/890/4085/983/1026/84515/641/4171/23279/9861/79902/4194/9656/5519/4998/6119/3364/7341/5701/10524/699/10926/5698/5708/22919/5985/990/995/165918/84126/4175/5710/1111/5702/7157/8900/5984/7324/11004/5704/6233/55388/701/672/7514/23595/7311/9025/5347/5983/6117/7334/5001/7465/5884/5810/55746/5696/4999/4176/7529/7314/4193 108 Orf_virus R-HSA-162599 Late Phase of HIV Life Cycle 67/1579 139/10654 6.3674247808131465e-21 1.090002584189198e-19 4.541861166369488e-20 23165/5905/2963/6917/5434/5440/5903/55706/7175/9631/2959/5430/6874/5436/404672/6749/348995/79023/57122/5441/23636/5438/10762/5431/23511/5435/4686/7316/5433/6872/2960/53371/23279/4927/9688/2966/8731/79902/2962/9883/5437/23225/2965/2068/5439/2071/8086/6233/2968/7514/1025/7311/9972/2967/6908/8021/7251/11198/129401/2961/5432/55746/22916/8480/2957/7314/25920 67 Orf_virus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 30/1579 35/10654 1.6017756868457313e-20 2.706376842319865e-19 1.1277026366719776e-19 23165/5903/55706/7175/9631/7884/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/1977/9972/8021/129401/55746/22916/8480 30 Orf_virus R-HSA-909733 Interferon alpha/beta signaling 44/1579 69/10654 1.8038943086411098e-20 3.008803199412928e-19 1.2537187165319454e-19 3665/5777/10379/5770/3455/9021/54739/4600/9636/2537/11274/8638/2634/3662/3394/3663/8519/3664/3434/6772/8651/3659/3433/3106/1958/25939/4939/3454/3661/3439/4599/3716/4940/91543/3437/3456/6773/4938/7297/5781/3430/3105/5696/3660 44 Orf_virus R-HSA-8878166 Transcriptional regulation by RUNX2 61/1579 121/10654 2.016371303286148e-20 3.320631728576302e-19 1.3836525265721068e-19 8454/57154/8493/7291/25/1019/8841/23462/10273/207/5594/3280/6500/4086/5925/10013/5705/3678/7316/9978/891/865/4094/9759/983/1026/10413/579/6772/6714/2099/9861/4089/2932/5701/6502/2908/5698/5708/2101/1749/595/55294/4488/5710/5702/23314/861/5704/6233/7525/7311/25937/367/860/1750/133522/5696/10891/7314/5595 61 Orf_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 63/1579 129/10654 4.010984232673463e-20 6.522863108385218e-19 2.717969578719517e-19 8454/3665/3725/5601/351/4790/6885/5604/8737/3684/29110/5594/4214/6500/841/7099/4615/5528/7316/79155/5970/4792/4205/9261/59307/8651/3146/7867/5519/5598/1432/4208/329/23291/5602/114609/6288/2002/3661/695/3654/7189/5609/6233/1385/2353/6196/7311/7187/1386/8772/5599/5600/7334/7097/3929/3551/6416/5781/3689/4791/7314/5595 63 Orf_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 52/1579 94/10654 5.915638447878871e-20 9.501537803321496e-19 3.959134243869549e-19 8454/3665/3725/5601/351/4790/6885/5604/8737/29110/5594/6500/841/7098/5528/7316/79155/5970/4792/4205/9261/3146/7867/5519/5598/1432/4208/329/23291/5602/6288/2002/3661/3654/7189/5609/6233/1385/2353/6196/7311/7187/1386/8772/5599/5600/7334/3551/6416/4791/7314/5595 52 Orf_virus R-HSA-3899300 SUMOylation of transcription cofactors 34/1579 45/10654 9.033412155303137e-20 1.4332279529328514e-18 5.972024723980894e-19 1912/1487/8204/8535/6045/51588/4869/80012/6613/28996/1655/9612/1911/7341/1387/84733/10401/10521/1616/2033/57332/7329/4152/10155/6612/9063/25942/6294/7703/11315/8648/10891/6015/8554 34 Orf_virus R-HSA-159227 Transport of the SLBP independent Mature mRNA 29/1579 34/10654 9.415868438265604e-20 1.4759090166486205e-18 6.149869683838664e-19 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/1977/9972/8021/129401/55746/22916/8480 29 Orf_virus R-HSA-5683057 MAPK family signaling cascades 105/1579 294/10654 1.6189247385125566e-19 2.5074060533390905e-18 1.0447947873859232e-18 2308/818/27161/2118/3725/815/9462/6464/6711/1437/3667/2309/1844/5604/3561/5747/3815/5567/8844/817/84292/1439/57690/5594/5568/2322/3315/27327/409/3082/2064/5705/1438/192670/2260/5528/7316/9978/1950/3560/2263/4233/983/5597/3718/6714/5605/4609/9861/5566/6710/5519/2261/5701/5159/3558/3717/2247/8649/5698/5708/2335/2534/408/1445/5710/816/5702/192669/1847/5979/23112/5704/6233/2885/6709/3716/7514/7311/5155/1956/60/4254/1843/4343/3570/3845/3265/3559/26523/4763/7297/5781/8202/3569/5062/5696/5245/7529/5156/7314/3572/5879/28956/5595 105 Orf_virus R-HSA-166166 MyD88-independent TLR4 cascade 53/1579 99/10654 1.916156216308752e-19 2.898743299322891e-18 1.2078585696438277e-18 8454/3665/3725/5601/351/4790/6885/5604/8737/29110/5594/6500/841/7099/5528/7316/79155/5970/4792/4205/9261/3146/7867/5519/5598/1432/4208/329/23291/5602/6288/2002/3661/3654/7189/5609/6233/1385/2353/6196/7311/7187/1386/8772/5599/5600/7334/3551/6416/5781/4791/7314/5595 53 Orf_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 53/1579 99/10654 1.916156216308752e-19 2.898743299322891e-18 1.2078585696438277e-18 8454/3665/3725/5601/351/4790/6885/5604/8737/29110/5594/6500/841/7099/5528/7316/79155/5970/4792/4205/9261/3146/7867/5519/5598/1432/4208/329/23291/5602/6288/2002/3661/3654/7189/5609/6233/1385/2353/6196/7311/7187/1386/8772/5599/5600/7334/3551/6416/5781/4791/7314/5595 53 Orf_virus R-HSA-69002 DNA Replication Pre-Initiation 48/1579 85/10654 5.021521613854739e-19 7.509194965086225e-18 3.128957811415838e-18 1017/4172/6118/5000/8318/23594/8317/54107/4173/5705/5557/7316/5422/1869/4174/84515/5426/4171/1871/9861/51053/4998/6119/5701/10926/5427/5698/5708/990/4175/5710/81620/5702/5704/6233/55388/29935/23595/7311/23649/6117/5001/5558/5696/4999/4176/7314/56655 48 Orf_virus R-HSA-168253 Host Interactions with Influenza Factors 32/1579 42/10654 7.201984354504118e-19 1.0647479142283929e-17 4.436629117906244e-18 3839/23165/3837/3838/5903/55706/7175/9631/348995/9636/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/3840/9883/23225/8086/3836/9972/5610/8021/7040/129401/55746/8480 32 Orf_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 51/1579 95/10654 7.892461575792056e-19 1.1408991677894961e-17 4.753938843898139e-18 8454/3725/5601/351/4790/6885/5604/5594/4214/6500/7099/4615/5528/7316/79155/5970/4792/4205/9261/59307/8651/3146/7867/5519/5598/1432/4208/23291/5602/114609/6288/2002/695/3654/7189/5609/6233/1385/2353/6196/7311/1386/5599/5600/7334/7097/3551/6416/4791/7314/5595 51 Orf_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 51/1579 95/10654 7.892461575792056e-19 1.1408991677894961e-17 4.753938843898139e-18 8454/3725/5601/351/4790/6885/5604/5594/4214/6500/7099/4615/5528/7316/79155/5970/4792/4205/9261/59307/8651/3146/7867/5519/5598/1432/4208/23291/5602/114609/6288/2002/695/3654/7189/5609/6233/1385/2353/6196/7311/1386/5599/5600/7334/7097/3551/6416/4791/7314/5595 51 Orf_virus R-HSA-168276 NS1 Mediated Effects on Host Pathways 31/1579 40/10654 1.070097310925465e-18 1.529886375290143e-17 6.374784443338513e-18 3839/23165/3837/3838/5903/55706/7175/9631/348995/9636/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/3840/9883/23225/8086/3836/9972/5610/8021/129401/55746/8480 31 Orf_virus R-HSA-4085377 SUMOylation of SUMOylation proteins 28/1579 34/10654 2.6802152990208586e-18 3.7901740261153664e-17 1.5793030652125198e-17 23165/5903/55706/7175/9631/51588/348995/79023/6613/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/7341/23225/8086/7329/9972/8021/129401/55746/8480 28 Orf_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 34/1579 48/10654 2.718405627390896e-18 3.8028448615436077e-17 1.5845827935555307e-17 5295/5777/6464/5290/1437/3561/1439/1438/6776/7316/3560/3055/6850/3718/5566/8503/867/3558/4067/3717/3636/2534/6233/2885/7525/3716/7409/7311/9846/5296/6777/3559/5781/7314 34 Orf_virus R-HSA-2219528 PI3K/AKT Signaling in Cancer 52/1579 101/10654 4.072114972894996e-18 5.635980403974884e-17 2.3484201691387712e-17 5295/2308/5290/3667/2309/842/3815/207/4303/84335/1027/7249/930/3082/941/2064/6199/2260/2100/1950/2263/4233/1026/6714/2099/64223/8503/2932/2261/5159/2247/3164/5880/2534/5728/942/2885/79109/2475/7409/1385/3932/2931/5155/1956/4254/5296/5781/5156/5879/253260/4193 52 Orf_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 51/1579 98/10654 4.6845710084684596e-18 6.348569668768194e-17 2.6453443742996237e-17 8454/3725/5601/351/4790/6885/5604/5594/4214/6500/7099/4615/5528/7316/79155/5970/4792/4205/9261/59307/8651/3146/7867/5519/5598/1432/4208/23291/5602/114609/6288/2002/695/3654/7189/5609/6233/1385/2353/6196/7311/1386/5599/5600/7334/7097/3551/6416/4791/7314/5595 51 Orf_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 51/1579 98/10654 4.6845710084684596e-18 6.348569668768194e-17 2.6453443742996237e-17 8454/3725/5601/351/4790/6885/5604/5594/4214/6500/7099/4615/5528/7316/79155/5970/4792/4205/9261/59307/8651/3146/7867/5519/5598/1432/4208/23291/5602/114609/6288/2002/695/3654/7189/5609/6233/1385/2353/6196/7311/1386/5599/5600/7334/7097/3551/6416/4791/7314/5595 51 Orf_virus R-HSA-877300 Interferon gamma signaling 49/1579 92/10654 5.961360366132159e-18 7.995597769420556e-17 3.3316338454238326e-17 3665/818/3460/5777/815/10379/115362/960/5770/7412/817/2633/9021/9830/3383/8638/7706/2634/3662/3394/3663/3664/567/6672/6772/8651/3659/3106/3459/4939/7341/3717/5771/3458/816/3661/10346/5371/5580/3716/3127/4940/4938/5781/4261/3105/3660/5724/8554 49 Orf_virus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 40/1579 65/10654 6.4355435837950045e-18 8.543512451548266e-17 3.559940865364584e-17 2176/3725/2963/6917/5434/5440/4436/5430/5436/404672/6749/545/472/5441/5438/5431/5435/5433/1643/2966/2962/9656/5437/2177/2965/2068/5439/1111/2071/7157/55215/2968/672/1025/2353/2967/1386/11198/5432/25920 40 Orf_virus R-HSA-451927 Interleukin-2 family signaling 32/1579 44/10654 7.614763269646353e-18 1.0006875771525158e-16 4.169700248663341e-17 5295/5777/6464/5290/1437/3561/3578/6775/1439/1438/3581/6776/3560/50615/6774/6850/3718/6772/8503/3558/3717/3636/2885/3716/9846/3932/5296/6777/3600/3559/3601/59067 32 Orf_virus R-HSA-168898 Toll-like Receptor Cascades 67/1579 155/10654 9.155020796052003e-18 1.1910682055663656e-16 4.96298495785977e-17 54106/8454/3665/3725/5601/351/4790/6885/5604/7184/8737/3684/29110/5594/4214/6500/841/7099/4615/7098/5528/7316/79155/5970/4792/4205/9261/59307/8651/3146/7867/5519/5598/1432/4208/329/23291/5602/114609/6288/2002/3661/695/3654/7189/5609/6233/51311/1385/2353/6196/7311/7187/1386/8772/5599/5600/7334/7097/3929/3551/6416/5781/3689/4791/7314/5595 67 Orf_virus R-HSA-166208 mTORC1-mediated signalling 22/1579 23/10654 1.0021020649089957e-17 1.290826521234261e-16 5.378661421866939e-17 6194/389541/84335/58528/6198/153129/64223/10325/8649/1981/6009/1977/10542/1975/2475/55004/10670/1978/64121/57521/7529/28956 22 Orf_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 49/1579 93/10654 1.0817445330992592e-17 1.3663588714195496e-16 5.693392279469784e-17 54106/8454/3665/3725/5601/351/4790/6885/5604/5594/4214/6500/7099/4615/5528/7316/79155/5970/4792/4205/9261/3146/7867/5519/5598/1432/4208/23291/5602/6288/2002/3654/7189/5609/6233/51311/1385/2353/6196/7311/1386/5599/5600/7334/3551/6416/4791/7314/5595 49 Orf_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 49/1579 93/10654 1.0817445330992592e-17 1.3663588714195496e-16 5.693392279469784e-17 54106/8454/3665/3725/5601/351/4790/6885/5604/5594/4214/6500/7099/4615/5528/7316/79155/5970/4792/4205/9261/3146/7867/5519/5598/1432/4208/23291/5602/6288/2002/3654/7189/5609/6233/51311/1385/2353/6196/7311/1386/5599/5600/7334/3551/6416/4791/7314/5595 49 Orf_virus R-HSA-1226099 Signaling by FGFR in disease 39/1579 63/10654 1.2426006280224134e-17 1.5544455933241922e-16 6.477118658213997e-17 5295/2963/8805/5434/5440/11052/26127/5290/5335/5430/5436/613/5441/2260/5438/9208/5431/6776/5435/4686/5433/6774/2263/6772/2962/399687/2261/5437/2247/5439/2885/9846/3845/6777/3265/5432/22916/7750/1523 39 Orf_virus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 41/1579 69/10654 1.51984587976803e-17 1.8831614186459115e-16 7.846823339153238e-17 23165/6118/5903/573/55706/7175/9631/7531/5594/348995/545/79023/472/57122/23636/3313/10762/23511/53371/9261/23279/4927/9688/79902/6119/9883/2932/23225/6767/8086/22824/9972/23411/8021/6117/129401/3312/3297/55746/8480/5595 41 Orf_virus R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 23/1579 25/10654 1.6453632482540506e-17 2.0194505528099241e-16 8.414717704576327e-17 10694/84617/51807/10575/10382/7277/10381/7278/112714/7203/10576/908/6950/7846/113457/347733/10376/10574/10383/84790/22948/10693/7280 23 Orf_virus R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 26/1579 31/10654 1.849285298326842e-17 2.239403336635561e-16 9.331224712709365e-17 23165/3837/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/3836/9972/8021/129401/55746/8480 26 Orf_virus R-HSA-2559583 Cellular Senescence 77/1579 195/10654 1.8589973893669532e-17 2.239403336635561e-16 9.331224712709365e-17 1912/1017/3725/9134/1019/5601/11065/4790/3159/7290/1029/2146/8535/6045/57690/5594/1027/27327/80012/5931/5925/1051/472/192670/3576/3490/8881/29855/7316/2114/1869/890/6774/5970/1026/9261/1911/6667/1871/7867/4194/5598/3552/5928/1432/10524/84733/5602/23512/57332/25842/192669/7157/8900/23135/7324/23112/5609/6233/2353/6196/7311/4343/8726/5599/5600/23466/4217/26523/3456/2113/6416/3569/7314/6015/5595/4193 77 Orf_virus R-HSA-1433557 Signaling by SCF-KIT 31/1579 43/10654 3.8040081983217124e-17 4.540380427538117e-16 1.8919017113816338e-16 5295/5777/5290/3815/4318/6776/9306/6774/6772/6714/8651/8503/867/4067/3717/2534/1111/2885/7525/7409/9846/3932/4254/5296/3845/6777/3265/5781/10603/5879/2242 31 Orf_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 48/1579 92/10654 3.9462320130246334e-17 4.66731622631368e-16 1.9447937671843886e-16 54106/8454/3725/5601/351/4790/6885/5604/5594/4214/6500/7099/4615/5528/7316/79155/5970/4792/4205/9261/3146/7867/5519/5598/1432/4208/23291/5602/6288/2002/3654/7189/5609/6233/51311/1385/2353/6196/7311/1386/5599/5600/7334/3551/6416/4791/7314/5595 48 Orf_virus R-HSA-177243 Interactions of Rev with host cellular proteins 28/1579 36/10654 4.4515610231634604e-17 5.21755035237447e-16 2.1740672611941035e-16 23165/5905/3837/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/7514/9972/8021/129401/55746/8480 28 Orf_virus R-HSA-9009391 Extra-nuclear estrogen signaling 43/1579 77/10654 6.194611671218613e-17 7.1957051645137645e-016 2.998331776952618e-16 5295/2788/596/5590/6464/5290/54331/4316/2309/5747/2770/207/5594/1027/3315/4318/2100/4313/1950/4314/6714/2099/8503/3320/4846/595/2783/2782/2002/2786/2771/7514/1385/2353/1956/5296/3845/3276/3265/3480/2773/5595/2787 43 Orf_virus R-HSA-69481 G2/M Checkpoints 69/1579 168/10654 7.874387989253113e-17 9.065998915060441e-16 3.777652365594181e-16 1017/4172/6118/5000/8318/9156/23594/7531/8317/51588/5982/63967/4173/11200/545/9133/472/5705/7336/11073/7316/4174/891/993/983/84515/641/4171/9861/9656/4998/6119/3364/7341/5701/10524/10926/5698/5708/5985/990/995/165918/84126/4175/5710/1111/5702/7157/5984/5704/6233/55388/672/23595/7311/9025/5983/6117/7334/5001/7465/5884/5810/5696/4999/4176/7529/7314 69 Orf_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 49/1579 97/10654 1.0464151588517331e-16 1.1941983523386883e-15 4.976027763699378e-16 54106/8454/3665/3725/5601/351/4790/6885/5604/5594/4214/6500/7099/4615/5528/7316/79155/5970/4792/4205/9261/3146/7867/5519/5598/1432/4208/23291/5602/6288/2002/3654/7189/5609/6233/51311/1385/2353/6196/7311/1386/5599/5600/7334/3551/6416/4791/7314/5595 49 Orf_virus R-HSA-9018519 Estrogen-dependent gene expression 64/1579 150/10654 1.1022614094120374e-16 1.2469931249087483e-15 5.196014881896561e-16 3727/27161/3725/2354/2963/3838/596/5434/5440/5241/8204/5430/5436/5451/2625/57690/27327/5441/192670/5438/5431/5885/5435/5433/865/5469/1655/6667/2099/4609/2962/8850/10524/1387/5437/3320/2033/8243/9126/595/5439/192669/3065/861/23028/23112/10498/3326/1025/2353/1386/6908/3169/4343/3276/26523/8202/5432/8648/2288/10728/2957/7528/6387 64 Orf_virus R-HSA-5693532 DNA Double-Strand Break Repair 68/1579 166/10654 1.5568608588979865e-16 1.746099980539897e-15 7.275710910457923e-16 1017/6118/54962/25/3838/2237/151987/5888/9156/51588/5982/63967/54107/5531/11200/545/472/6613/7336/51567/3981/11073/5591/7316/890/5425/641/5111/5426/9656/6119/84464/3364/22976/7341/10524/5427/5985/165918/84126/142/8914/1111/7157/8900/5984/7329/6233/51426/672/7311/6047/9025/3980/5983/6117/5599/7334/5981/10038/2547/5884/5810/5424/348654/55183/7314/56655 68 Orf_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 32/1579 47/10654 1.7194484187600728e-16 1.9119678570998757e-15 7.966855021695344e-16 8454/8841/9734/23462/51564/55534/3280/6500/84441/3091/10013/10046/7316/9978/9611/9759/9612/4609/10014/8850/1387/2033/55294/3066/3065/9794/6233/7311/388585/3516/4851/7314 32 Orf_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 45/1579 85/10654 1.841822994449621e-16 1.9968430964824642e-15 8.320516159136446e-16 8454/3725/5601/351/4790/6885/5604/5594/4214/6500/4615/5528/7316/79155/5970/4792/4205/9261/3146/7867/5519/5598/1432/4208/23291/5602/6288/2002/3654/7189/5609/6233/1385/2353/6196/7311/1386/5599/5600/7334/3551/6416/4791/7314/5595 45 Orf_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 45/1579 85/10654 1.841822994449621e-16 1.9968430964824642e-15 8.320516159136446e-16 8454/3725/5601/351/4790/6885/5604/5594/4214/6500/4615/5528/7316/79155/5970/4792/4205/9261/3146/7867/5519/5598/1432/4208/23291/5602/6288/2002/3654/7189/5609/6233/1385/2353/6196/7311/1386/5599/5600/7334/3551/6416/4791/7314/5595 45 Orf_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 45/1579 85/10654 1.841822994449621e-16 1.9968430964824642e-15 8.320516159136446e-16 8454/3725/5601/351/4790/6885/5604/5594/4214/6500/4615/5528/7316/79155/5970/4792/4205/9261/3146/7867/5519/5598/1432/4208/23291/5602/6288/2002/3654/7189/5609/6233/1385/2353/6196/7311/1386/5599/5600/7334/3551/6416/4791/7314/5595 45 Orf_virus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 30/1579 42/10654 1.8829658299603366e-16 2.0245773097342134e-15 8.436080055933652e-16 23165/5903/55706/7175/9631/7884/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/1977/9972/8021/129401/55746/22916/8480 30 Orf_virus R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 27/1579 35/10654 2.373172626091354e-16 2.5307357266761075e-15 1.0545158778576766e-15 23165/5903/55706/7175/9631/348995/79023/9133/57122/23636/10762/23511/891/53371/983/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 27 Orf_virus R-HSA-180746 Nuclear import of Rev protein 26/1579 33/10654 3.434049872049782e-16 3.602982970594166e-15 1.5013036367620014e-15 23165/3837/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 26 Orf_virus R-HSA-180910 Vpr-mediated nuclear import of PICs 26/1579 33/10654 3.434049872049782e-16 3.602982970594166e-15 1.5013036367620014e-15 23165/5903/55706/7175/9631/3159/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/3836/9972/8021/129401/55746/8480 26 Orf_virus R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 25/1579 31/10654 4.714895515108864e-16 4.907263252125306e-15 2.0447757391840548e-15 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/7514/9972/8021/129401/55746/8480 25 Orf_virus R-HSA-72086 mRNA Capping 24/1579 29/10654 6.053540462837481e-16 6.2505207477393356e-15 2.6044890044789495e-15 2963/5434/5440/5430/5436/404672/5441/5438/5431/5435/4686/5433/2966/8731/2962/5437/2965/2068/5439/2071/2968/2967/5432/22916 24 Orf_virus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 34/1579 54/10654 7.267131209412303e-16 7.416709308826794e-15 3.0904205623575378e-15 9318/6917/5434/5440/5430/5436/404672/5441/7507/5438/5431/8450/5435/7316/9978/5433/2966/10980/5437/1642/2965/2033/2068/5439/10987/2071/6233/2968/7311/2967/7874/5432/7314/8451 34 Orf_virus R-HSA-429947 Deadenylation of mRNA 22/1579 25/10654 7.411008533032154e-16 7.416709308826794e-15 3.0904205623575378e-15 9924/5073/4849/4850/255967/26986/10605/9337/25904/246175/4848/23019/1981/1973/1977/1975/55571/9775/57472/85456/29883/1974 22 Orf_virus R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 22/1579 25/10654 7.411008533032154e-16 7.416709308826794e-15 3.0904205623575378e-15 6118/5982/54107/3978/7316/5425/5111/5426/6119/5427/5985/5984/6233/51426/7311/3980/5983/6117/5981/5424/7314/56655 22 Orf_virus R-HSA-8854691 Interleukin-20 family signaling 22/1579 25/10654 7.411008533032154e-16 7.416709308826794e-15 3.0904205623575378e-15 6775/50616/11009/53833/6776/6774/3718/6772/3717/29949/163702/58985/3716/282618/53832/50604/3588/6777/55801/6773/7297/5781 22 Orf_virus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 29/1579 41/10654 9.230993427877448e-16 9.167574389059968e-15 3.81997719193e-15 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/1977/9972/8021/129401/55746/22916/8480 29 Orf_virus R-HSA-448424 Interleukin-17 signaling 40/1579 72/10654 9.689459648558075e-16 9.549990153616708e-15 3.979323539878316e-15 8454/3605/3725/5601/4790/6885/5604/5594/6500/5528/7316/79155/4205/9261/7867/5519/5598/1432/4208/23291/5602/2002/3654/7189/112744/5609/6233/1385/2353/6196/7311/1386/5599/5600/7334/3551/23765/6416/7314/5595 40 Orf_virus R-HSA-165054 Rev-mediated nuclear export of HIV RNA 26/1579 34/10654 1.2543118382343876e-15 1.2269621816112318e-14 5.112549241715153e-15 23165/5905/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/7514/9972/8021/129401/55746/8480 26 Orf_virus R-HSA-2980766 Nuclear Envelope Breakdown 33/1579 52/10654 1.3828798142150798e-15 1.3366375599971699e-14 5.569548472013774e-15 4000/23165/5903/55706/7175/9631/348995/79023/9133/57122/23636/7443/10762/23511/891/53371/983/23279/4927/9688/79902/9883/23225/8086/2010/64900/9972/5347/8021/129401/55746/7112/8480 33 Orf_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 58/1579 134/10654 1.386979789389838e-15 1.3366375599971699e-14 5.569548472013774e-15 5295/8454/3725/5601/6464/4773/5290/2205/5335/4790/6885/4772/5532/5594/4775/4214/6500/5705/2206/5530/7316/5970/4792/6850/9861/5701/4067/23291/5698/5708/5602/2534/5710/5702/695/7189/5609/5704/6233/2885/7409/2353/7311/9846/5296/3845/5599/7334/3265/3551/6416/5062/5696/997/2207/7314/5879/5595 58 Orf_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 46/1579 92/10654 1.5179070296343872e-15 1.4520566511428954e-14 6.050480806979176e-15 1017/6118/9156/6874/22974/9212/5982/1460/6749/11200/545/472/11073/7316/6872/28996/890/1457/6790/641/4194/6119/3364/1432/10524/5985/84126/1111/7157/8900/5984/6233/672/7311/6908/8851/5300/5983/6117/11198/5600/1020/5884/5810/7314/4193 46 Orf_virus R-HSA-5654738 Signaling by FGFR2 40/1579 73/10654 1.8404086756038084e-15 1.746607769000223e-14 7.277826781302761e-15 5295/2963/10253/5434/5440/6464/5290/5335/5430/5436/5594/3178/5441/5438/5431/5435/4686/7316/5433/2263/6714/8569/2962/867/5437/4670/2247/5439/6233/2885/3187/7311/3845/3265/5781/5432/22916/5725/7314/5595 40 Orf_virus R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 25/1579 32/10654 1.8526661961724115e-15 1.746607769000223e-14 7.277826781302761e-15 10694/84617/51807/10575/10382/7277/10381/7278/112714/7203/10576/908/6950/7846/113457/347733/10376/10574/10383/60/84790/22948/10693/7280/5201 25 Orf_virus R-HSA-450294 MAP kinase activation 37/1579 64/10654 2.020006112146023e-15 1.8906675912963854e-14 7.878100323780401e-15 8454/3725/5601/4790/6885/5604/5594/6500/5528/7316/79155/4205/9261/7867/5519/5598/1432/4208/23291/5602/2002/3654/7189/5609/6233/1385/2353/6196/7311/1386/5599/5600/7334/3551/6416/7314/5595 37 Orf_virus R-HSA-8878159 Transcriptional regulation by RUNX3 47/1579 96/10654 2.1304099615197826e-15 1.9797595428123124e-14 8.249331805884872e-15 57154/2309/1499/10018/1029/55534/3280/84441/463/5705/6097/10046/7316/865/9759/1026/10413/6714/6934/4609/9861/4089/8850/5701/1387/4088/5698/5708/2033/595/5710/5702/7157/861/9794/5704/6233/7311/25937/7040/3845/3516/4851/5696/3676/7314/4193 47 Orf_virus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 24/1579 30/10654 2.6020916980449535e-15 2.4009370916003438e-14 1.0004309253401649e-14 6118/5982/54107/8450/7316/9978/5425/5111/5426/6119/5427/1642/5985/5984/6233/7311/5983/6117/5981/5424/7314/51514/8451/56655 24 Orf_virus R-HSA-162909 Host Interactions of HIV factors 56/1579 129/10654 3.679967187010979e-15 3.3715755706347065e-14 1.4048799861457776e-14 23165/5905/3837/164/5903/55706/7175/9631/3159/4869/6500/348995/79023/57122/5705/23636/10762/919/23511/7316/9978/53371/920/567/3055/926/23279/4927/9688/9861/79902/9883/5701/23225/5698/5708/2534/5710/5702/8086/3836/5704/6233/7514/1025/7311/9972/3932/8021/129401/5062/55746/5696/8480/7314/5879 56 Orf_virus R-HSA-70171 Glycolysis 39/1579 71/10654 3.713534775908005e-15 3.3785375828365835e-14 1.407780941915806e-14 23165/5903/2597/55706/7175/9631/5315/5567/5568/348995/79023/57122/23636/5214/10762/23511/5528/229/53371/5230/23279/4927/9688/79902/5566/5519/9883/2023/226/23225/2821/8086/5213/9972/8021/129401/2026/55746/8480 39 Orf_virus R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 21/1579 24/10654 4.454271351898183e-15 3.996556571599681e-14 1.6652992713085768e-14 6118/2237/5982/54107/3978/5557/5422/5425/5111/5426/6119/5427/5985/5984/23649/5983/6117/5981/5558/5424/56655 21 Orf_virus R-HSA-982772 Growth hormone receptor signaling 21/1579 24/10654 4.454271351898183e-15 3.996556571599681e-14 1.6652992713085768e-14 5777/3667/5770/2690/9021/5594/6776/6774/6772/8651/1442/4067/3717/5618/2688/1154/5617/8835/6777/2689/5595 21 Orf_virus R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 25/1579 33/10654 6.5691074741956455e-15 5.853704673923654e-14 2.4391422849392623e-14 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/7514/9972/8021/129401/55746/8480 25 Orf_virus R-HSA-5693538 Homology Directed Repair 58/1579 138/10654 6.890686094842218e-15 6.098491571013419e-14 2.5411409515529842e-14 1017/6118/54962/25/2237/151987/5888/9156/51588/5982/63967/54107/5531/545/472/6613/7336/11073/7316/890/5425/641/5111/5426/9656/6119/84464/3364/7341/10524/5427/5985/165918/84126/142/8914/1111/8900/5984/7329/6233/51426/672/7311/6047/9025/3980/5983/6117/7334/5981/10038/5884/5810/5424/348654/7314/56655 58 Orf_virus R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 24/1579 31/10654 9.907013343304597e-15 8.650351919220994e-14 3.604459111128129e-14 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 24 Orf_virus R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 24/1579 31/10654 9.907013343304597e-15 8.650351919220994e-14 3.604459111128129e-14 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 24 Orf_virus R-HSA-176033 Interactions of Vpr with host cellular proteins 26/1579 36/10654 1.2971388432818267e-14 1.125051756739771e-13 4.687905293264145e-14 23165/5903/55706/7175/9631/3159/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/3836/9972/8021/129401/55746/8480 26 Orf_virus R-HSA-8851708 Signaling by FGFR2 IIIa TM 18/1579 19/10654 1.792206399743097e-14 1.544146043752165e-13 6.434202132225129e-14 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2263/2962/5437/2247/5439/5432/22916 18 Orf_virus R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 22/1579 27/10654 1.9240397159351632e-14 1.6360625296938872e-13 6.817202983877599e-14 2963/5434/5440/5430/5436/404672/5441/5438/5431/5435/5433/2966/8731/2962/5437/2965/2068/5439/2071/2968/2967/5432 22 Orf_virus R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 22/1579 27/10654 1.9240397159351632e-14 1.6360625296938872e-13 6.817202983877599e-14 2963/5434/5440/5430/5436/404672/5441/5438/5431/5435/5433/2966/8731/2962/5437/2965/2068/5439/2071/2968/2967/5432 22 Orf_virus R-HSA-8878171 Transcriptional regulation by RUNX1 82/1579 239/10654 2.3434113571952153e-14 1.9797260881240097e-13 8.249192405711112e-14 1912/6595/9070/27161/25/4773/2624/1437/11091/6597/640/8535/8085/6045/9021/2625/57690/5929/27327/80012/1460/4005/6598/5705/6599/192670/100506658/7316/865/28996/1457/1911/10413/6714/2099/122809/9861/8850/5701/1387/84733/3558/6604/8289/5698/5708/10138/2033/6605/6602/57332/595/50943/5710/3458/5702/192669/3065/83737/861/1998/5371/23112/5704/6233/7311/6688/7161/860/58508/25942/4343/3276/3977/6601/3559/23466/26523/5781/5696/7314/6015 82 Orf_virus R-HSA-68886 M Phase 116/1579 395/10654 3.5958555844324006e-14 3.012960215753347e-13 1.2554508767449926e-13 4000/23165/5905/11130/84617/5903/10403/11065/55706/7175/55143/64151/22981/9631/7531/1058/991/203068/79019/54801/51807/10382/9212/5594/3619/5925/1460/23244/7277/348995/79023/9133/10381/57122/5705/23636/23310/7278/6232/332/7443/112714/1780/10762/8881/10051/5885/23511/5528/7316/891/53371/4085/1457/983/1639/23279/4927/9688/9861/79902/5566/5519/9883/5701/10112/699/7846/23225/113457/5698/347733/5708/3320/22919/8243/9126/10376/10426/23397/5710/9918/5702/10540/10733/1069/8086/7324/2010/64900/11004/9232/5704/6233/9700/701/7514/7311/9972/55844/10383/5347/54892/84790/8021/9493/129401/6418/55746/7112/5696/10592/7280/8480/7314/5595 116 Orf_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 40/1579 78/10654 3.6127732025943285e-14 3.012960215753347e-13 1.2554508767449926e-13 3665/351/7186/4790/8737/29110/57506/4214/9636/841/7706/7316/5970/4792/3093/3146/23586/7128/1387/843/2033/64135/6288/83737/3661/9246/7189/3439/51191/6233/7311/5094/7187/8772/5300/1540/3551/3456/4791/7314 40 Orf_virus R-HSA-73893 DNA Damage Bypass 30/1579 48/10654 5.003864530969055e-14 4.1465144934972874e-13 1.7277842664760734e-13 6118/5982/54107/9636/7706/8450/7316/9978/5425/5111/5426/7415/6119/83932/5427/1642/5985/5984/9246/6233/51426/7311/5983/6117/5981/5424/7314/51514/8451/56655 30 Orf_virus R-HSA-4090294 SUMOylation of intracellular receptors 23/1579 30/10654 5.2478369049740764e-14 4.3211619071970087e-13 1.8005569660637237e-13 6095/7068/5241/5468/51588/6613/2516/5465/4929/9759/2099/7341/10401/2908/6256/7329/7376/367/6612/9063/7421/10062/8554 23 Orf_virus R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 22/1579 28/10654 7.722544769769936e-14 6.31888726130232e-13 2.63297620419167e-13 10694/84617/10575/10382/7277/10381/7278/7203/10576/908/6950/7846/113457/347733/10574/10383/60/84790/22948/10693/7280/5201 22 Orf_virus R-HSA-400253 Circadian Clock 37/1579 70/10654 9.589940620066985e-14 7.797820466691967e-13 3.2492233021937484e-13 8454/6095/8841/1374/5936/10135/8204/28999/1407/6500/3091/1408/5465/406/4209/7316/9611/5469/8553/4208/1387/2908/6604/1390/2033/6256/10498/6233/1385/7311/23054/1386/23411/23373/8648/10891/7314 37 Orf_virus R-HSA-113418 Formation of the Early Elongation Complex 24/1579 33/10654 1.074059142793834e-13 8.57270518266735e-13 3.5721049954073264e-13 2963/5434/5440/5430/5436/404672/5441/5438/5431/5435/4686/5433/2966/2962/5437/2965/2068/5439/2071/2968/2967/5432/22916/25920 24 Orf_virus R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 24/1579 33/10654 1.074059142793834e-13 8.57270518266735e-13 3.5721049954073264e-13 2963/5434/5440/5430/5436/404672/5441/5438/5431/5435/4686/5433/2966/2962/5437/2965/2068/5439/2071/2968/2967/5432/22916/25920 24 Orf_virus R-HSA-2559585 Oncogene Induced Senescence 24/1579 33/10654 1.074059142793834e-13 8.57270518266735e-13 3.5721049954073264e-13 1019/1029/57690/5594/27327/5925/192670/7316/2114/1869/6667/1871/4194/192669/7157/23112/6233/7311/4343/26523/2113/7314/5595/4193 24 Orf_virus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 30/1579 49/10654 1.1087020068137743e-13 8.795251895516588e-13 3.664836543704068e-13 1017/9134/7832/4849/1027/4869/4850/9337/1869/891/890/983/1026/6790/5111/25904/246175/1647/4848/23019/2033/995/7157/8900/10498/55571/57472/3276/85456/29883 30 Orf_virus R-HSA-190236 Signaling by FGFR 42/1579 87/10654 1.2322757854564218e-13 9.716307859871543e-13 4.048625387623969e-13 5295/2963/10253/5434/5440/6464/5290/5335/5430/5436/5594/3178/5441/2260/5438/5431/5435/4686/7316/5433/2263/6714/8569/2962/2261/867/5437/4670/2247/5439/6233/2885/3187/7311/3845/3265/5781/5432/22916/5725/7314/5595 42 Orf_virus R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 54/1579 132/10654 2.259212538892521e-13 1.770623803071789e-12 7.377897638108107e-13 1017/6118/54962/25/151987/5888/9156/51588/5982/63967/54107/5531/545/472/6613/7336/11073/7316/890/5425/641/5111/5426/9656/6119/84464/3364/7341/10524/5427/5985/165918/84126/8914/1111/8900/5984/7329/6233/51426/672/7311/6047/9025/5983/6117/7334/5981/5884/5810/5424/348654/7314/56655 54 Orf_virus R-HSA-191859 snRNP Assembly 31/1579 53/10654 2.5098913180454567e-13 1.9436717885578208e-12 8.098960080159213e-13 23165/5903/6632/55706/7175/6606/9631/25929/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/8086/9972/6634/8021/129401/55746/22916/8480/6628 31 Orf_virus R-HSA-194441 Metabolism of non-coding RNA 31/1579 53/10654 2.5098913180454567e-13 1.9436717885578208e-12 8.098960080159213e-13 23165/5903/6632/55706/7175/6606/9631/25929/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/8086/9972/6634/8021/129401/55746/22916/8480/6628 31 Orf_virus R-HSA-9607240 FLT3 Signaling 86/1579 267/10654 3.236730461334533e-13 2.491707887690075e-12 1.0382536204218528e-12 5295/54106/818/815/9462/6464/6711/5290/1437/3667/1844/5604/3561/5747/3815/8844/817/84292/1439/5594/2322/409/3082/2064/5705/1438/2260/6776/5528/7316/9978/1950/3560/2263/4233/3055/3718/6714/5605/9861/6710/5519/2261/5701/5159/3558/3717/2247/8649/5698/5708/2335/2534/408/1445/5710/816/5702/1847/5979/5704/6233/2885/6709/3716/7311/9846/5155/1956/60/4254/5296/1843/3845/6777/3265/3559/4763/5781/5696/5245/7529/5156/7314/28956/5595 86 Orf_virus R-HSA-5684996 MAPK1/MAPK3 signaling 83/1579 255/10654 4.468567279723674e-13 3.419768253482647e-12 1.4249610830078588e-12 818/815/9462/6464/6711/1437/3667/1844/5604/3561/5747/3815/8844/817/84292/1439/5594/2322/409/3082/2064/5705/1438/2260/5528/7316/9978/1950/3560/2263/4233/983/3718/6714/5605/9861/6710/5519/2261/5701/5159/3558/3717/2247/8649/5698/5708/2335/2534/408/1445/5710/816/5702/1847/5979/5704/6233/2885/6709/3716/7311/5155/1956/60/4254/1843/3570/3845/3265/3559/4763/7297/5781/3569/5696/5245/7529/5156/7314/3572/28956/5595 83 Orf_virus R-HSA-447115 Interleukin-12 family signaling 32/1579 57/10654 4.9675733574131e-13 3.779422770756984e-12 1.5748231942553072e-12 10148/1072/3592/27250/3593/6775/3595/1265/4478/3313/6175/6774/6772/6647/149233/6950/3717/9466/3458/3181/6648/3716/3594/2939/4507/302/51561/246778/7297/5062/3586/3572 32 Orf_virus R-HSA-2871796 FCERI mediated MAPK activation 23/1579 32/10654 5.346956971706308e-13 4.021035271786073e-12 1.6754991423357158e-12 3725/5601/6464/2205/5335/5594/4214/2206/6850/4067/5602/5609/2885/7409/2353/3845/5599/3265/6416/5062/2207/5879/5595 23 Orf_virus R-HSA-5656169 Termination of translesion DNA synthesis 23/1579 32/10654 5.346956971706308e-13 4.021035271786073e-12 1.6754991423357158e-12 6118/5982/54107/9636/7706/7316/5425/5111/5426/6119/5427/5985/5984/9246/6233/51426/7311/5983/6117/5981/5424/7314/56655 23 Orf_virus R-HSA-166520 Signaling by NTRKs 45/1579 101/10654 6.16394133688523e-13 4.608786022579129e-12 1.9204051957022946e-12 5295/4908/627/6464/5290/3667/5335/4915/5604/5594/7074/5528/6774/4205/9261/6714/5605/7867/5519/5598/1432/4208/4909/4914/2534/4803/5603/2002/2885/1385/6196/387/8851/5296/3845/5600/3265/6300/1020/5781/4916/7529/5879/5595/25920 45 Orf_virus R-HSA-5685942 HDR through Homologous Recombination (HRR) 35/1579 67/10654 7.09662747469648e-13 5.275835625474355e-12 2.1983537741165036e-12 6118/5888/9156/5982/54107/545/472/11073/7316/5425/641/5111/5426/6119/84464/3364/10524/5427/5985/84126/1111/5984/6233/51426/672/7311/5983/6117/5981/5884/5810/5424/348654/7314/56655 35 Orf_virus R-HSA-167169 HIV Transcription Elongation 28/1579 46/10654 9.10054018250308e-13 6.651574594065454e-12 2.771601533997094e-12 2963/6917/5434/5440/5430/5436/404672/6749/5441/5438/5431/5435/4686/5433/2966/2962/5437/2965/2068/5439/2071/2968/1025/2967/11198/5432/22916/25920 28 Orf_virus R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 28/1579 46/10654 9.10054018250308e-13 6.651574594065454e-12 2.771601533997094e-12 2963/6917/5434/5440/5430/5436/404672/6749/5441/5438/5431/5435/4686/5433/2966/2962/5437/2965/2068/5439/2071/2968/1025/2967/11198/5432/22916/25920 28 Orf_virus R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 28/1579 46/10654 9.10054018250308e-13 6.651574594065454e-12 2.771601533997094e-12 2963/6917/5434/5440/5430/5436/404672/6749/5441/5438/5431/5435/4686/5433/2966/2962/5437/2965/2068/5439/2071/2968/1025/2967/11198/5432/22916/25920 28 Orf_virus R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 18/1579 21/10654 9.300944229394505e-13 6.76007175555433e-12 2.8168105134596708e-12 6118/2237/328/5982/54107/3978/5425/5111/5426/6119/5427/5985/5984/5983/6117/5981/5424/56655 18 Orf_virus R-HSA-446652 Interleukin-1 family signaling 55/1579 140/10654 9.846470461823205e-13 7.116810039351105e-12 2.9654574782683925e-12 8454/3557/834/5777/351/4790/6885/5604/5783/27178/29110/3553/6500/5705/4615/7316/3565/9978/79155/6774/5970/4792/59307/3606/8809/3146/9861/3552/5701/23291/4088/5698/5708/5771/5710/6288/5702/3654/7189/5704/6233/7311/5599/5784/7334/3551/7850/6416/5781/5696/4791/3554/7314/3596/3556 55 Orf_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 31/1579 55/10654 9.967199831800448e-13 7.1642690503714824e-12 2.9852328661687874e-12 834/596/351/4790/6885/842/835/29108/841/7316/5970/7128/1432/329/837/598/5603/83737/3654/7189/6233/3326/7311/64170/5600/7334/1540/3551/6300/4791/7314 31 Orf_virus R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 25/1579 38/10654 1.2028083272426194e-12 8.598096888695867e-12 3.5826853009250954e-12 1912/6595/6597/8535/6045/80012/1460/6598/6599/865/28996/1457/1911/84733/6604/8289/10138/2033/6605/6602/57332/861/6601/23466/6015 25 Orf_virus R-HSA-167161 HIV Transcription Initiation 28/1579 47/10654 1.9346356138453436e-12 1.3388090072408469e-011 5.57859653488439e-12 2963/5434/5440/2959/5430/6874/5436/404672/5441/5438/5431/5435/5433/6872/2960/2966/2962/5437/2965/2068/5439/2071/2968/2967/6908/2961/5432/2957 28 Orf_virus R-HSA-167162 RNA Polymerase II HIV Promoter Escape 28/1579 47/10654 1.9346356138453436e-12 1.3388090072408469e-011 5.57859653488439e-12 2963/5434/5440/2959/5430/6874/5436/404672/5441/5438/5431/5435/5433/6872/2960/2966/2962/5437/2965/2068/5439/2071/2968/2967/6908/2961/5432/2957 28 Orf_virus R-HSA-73776 RNA Polymerase II Promoter Escape 28/1579 47/10654 1.9346356138453436e-12 1.3388090072408469e-011 5.57859653488439e-12 2963/5434/5440/2959/5430/6874/5436/404672/5441/5438/5431/5435/5433/6872/2960/2966/2962/5437/2965/2068/5439/2071/2968/2967/6908/2961/5432/2957 28 Orf_virus R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 28/1579 47/10654 1.9346356138453436e-12 1.3388090072408469e-011 5.57859653488439e-12 2963/5434/5440/2959/5430/6874/5436/404672/5441/5438/5431/5435/5433/6872/2960/2966/2962/5437/2965/2068/5439/2071/2968/2967/6908/2961/5432/2957 28 Orf_virus R-HSA-75953 RNA Polymerase II Transcription Initiation 28/1579 47/10654 1.9346356138453436e-12 1.3388090072408469e-011 5.57859653488439e-12 2963/5434/5440/2959/5430/6874/5436/404672/5441/5438/5431/5435/5433/6872/2960/2966/2962/5437/2965/2068/5439/2071/2968/2967/6908/2961/5432/2957 28 Orf_virus R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 28/1579 47/10654 1.9346356138453436e-12 1.3388090072408469e-011 5.57859653488439e-12 2963/5434/5440/2959/5430/6874/5436/404672/5441/5438/5431/5435/5433/6872/2960/2966/2962/5437/2965/2068/5439/2071/2968/2967/6908/2961/5432/2957 28 Orf_virus R-HSA-110373 Resolution of AP sites via the multiple-nucleotide patch replacement pathway 20/1579 26/10654 2.2042371266345625e-12 1.5093223693429294e-11 6.2890976189296375e-12 6118/2237/328/5982/54107/3978/5425/5111/5426/6119/5427/5985/142/5984/5983/6117/5981/10038/5424/56655 20 Orf_virus R-HSA-6803529 FGFR2 alternative splicing 20/1579 26/10654 2.2042371266345625e-12 1.5093223693429294e-11 6.2890976189296375e-12 2963/5434/5440/5430/5436/3178/5441/5438/5431/5435/4686/5433/2962/5437/4670/5439/3187/5432/22916/5725 20 Orf_virus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 79/1579 244/10654 2.256994960695918e-12 1.5373562533326644e-11 6.405910194314675e-12 23165/23451/2963/5434/5440/5903/220988/6632/55706/7175/10946/9631/7884/11051/5430/5436/6428/3184/3178/23450/348995/79023/57122/5441/23636/5438/10762/5431/5093/23511/5435/4686/5433/53371/11338/1655/9343/3190/56339/23279/4927/9688/79902/2962/988/9883/5437/4670/23225/10189/6631/10482/3181/5439/1660/8086/1977/10285/3187/1665/9972/6634/5094/51593/8021/9775/3192/129401/3312/10291/5432/55746/22916/56259/5725/8480/10992/6628/1994 79 Orf_virus R-HSA-877312 Regulation of IFNG signaling 14/1579 14/10654 2.3484565675103775e-12 1.5913239553807297e-11 6.630784716380725e-12 3460/5777/5770/9021/6772/8651/3459/7341/3717/5771/3458/3716/5781/8554 14 Orf_virus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 25/1579 39/10654 2.8806825603427764e-12 1.9418487103657785e-11 8.091363613725277e-12 6118/5982/54107/9636/7706/7316/5425/5111/5426/7415/6119/83932/5427/5985/5984/9246/6233/51426/7311/5983/6117/5981/5424/7314/56655 25 Orf_virus R-HSA-167172 Transcription of the HIV genome 36/1579 73/10654 3.1326391998045065e-12 2.1008059788379707e-11 8.753712359735869e-12 2963/6917/5434/5440/2959/5430/6874/5436/404672/6749/5441/5438/5431/5435/4686/5433/6872/2960/2966/8731/2962/5437/2965/2068/5439/2071/2968/1025/2967/6908/11198/2961/5432/22916/2957/25920 36 Orf_virus R-HSA-453274 Mitotic G2-G2/M phases 68/1579 198/10654 3.800107953121506e-12 2.535354075390297e-11 1.0564402676694064e-11 8454/1017/84617/994/2305/22981/7531/203068/54801/51807/22974/10382/3161/6500/7277/9133/10381/5705/7278/112714/7316/728642/9978/1869/891/993/890/983/1026/1639/6790/1871/9861/5566/5519/5928/5701/23291/7846/113457/5698/347733/5708/3320/22919/2033/995/10376/10426/5710/5702/10540/7157/10733/8900/1069/5704/6233/3326/7514/7311/10383/5347/84790/7465/5696/7280/7314 68 Orf_virus R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 28/1579 48/10654 3.990328617033345e-12 2.6486824136532557e-11 1.103662318889459e-11 2963/6917/5434/5440/5430/5436/404672/6749/5441/5438/5431/5435/4686/5433/2966/2962/5437/2965/2068/5439/2071/2968/1025/2967/11198/5432/22916/25920 28 Orf_virus R-HSA-390466 Chaperonin-mediated protein folding 42/1579 95/10654 4.993290055212487e-12 3.2975991684423583e-11 1.3740552382764792e-11 2788/10694/84617/9134/8841/54331/2770/51807/10575/10382/1460/7277/10381/7278/112714/7203/10576/908/6774/1457/6950/7846/113457/347733/10376/55294/2783/2782/7157/2786/2771/10574/6468/10383/60/84790/22948/10693/7280/2773/5201/2787 42 Orf_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 24/1579 37/10654 5.4230212231687844e-12 3.553756298354889e-11 1.4807916935578038e-11 1017/1029/207/11200/472/639/7316/890/983/64223/4194/5519/1616/9099/7157/8900/6233/79109/2475/7311/7874/7314/253260/4193 24 Orf_virus R-HSA-69186 Lagging Strand Synthesis 17/1579 20/10654 5.435799411011706e-12 3.553756298354889e-11 1.4807916935578038e-11 6118/2237/5982/3978/5557/5422/5425/5111/6119/5985/5984/23649/5983/6117/5981/5558/5424 17 Orf_virus R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 16/1579 18/10654 5.769580542871579e-12 3.753112143137962e-11 1.5638599892520332e-11 5295/8805/11052/26127/5290/613/9208/6776/6774/6772/399687/2885/9846/6777/7750/1523 16 Orf_virus R-HSA-68949 Orc1 removal from chromatin 35/1579 71/10654 6.370750211810721e-12 4.123555236599875e-11 1.718217522431276e-11 8454/1017/4172/5000/23594/6500/4173/5705/7316/9978/4174/890/84515/4171/9861/4998/5701/6502/5698/5708/990/4175/5710/81620/5702/8900/5704/6233/23595/7311/5001/5696/4999/4176/7314 35 Orf_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 31/1579 58/10654 6.6680464903101095e-12 4.211227419365753e-11 1.7547490763973973e-11 8454/8841/9734/23462/51564/55534/3280/6500/84441/10013/10046/7316/9978/9611/9759/9612/4609/10014/8850/1387/2033/55294/3066/3065/9794/6233/7311/388585/3516/4851/7314 31 Orf_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 31/1579 58/10654 6.6680464903101095e-12 4.211227419365753e-11 1.7547490763973973e-11 8454/8841/9734/23462/51564/55534/3280/6500/84441/10013/10046/7316/9978/9611/9759/9612/4609/10014/8850/1387/2033/55294/3066/3065/9794/6233/7311/388585/3516/4851/7314 31 Orf_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 31/1579 58/10654 6.6680464903101095e-12 4.211227419365753e-11 1.7547490763973973e-11 8454/8841/9734/23462/51564/55534/3280/6500/84441/10013/10046/7316/9978/9611/9759/9612/4609/10014/8850/1387/2033/55294/3066/3065/9794/6233/7311/388585/3516/4851/7314 31 Orf_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 31/1579 58/10654 6.6680464903101095e-12 4.211227419365753e-11 1.7547490763973973e-11 8454/8841/9734/23462/51564/55534/3280/6500/84441/10013/10046/7316/9978/9611/9759/9612/4609/10014/8850/1387/2033/55294/3066/3065/9794/6233/7311/388585/3516/4851/7314 31 Orf_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 31/1579 58/10654 6.6680464903101095e-12 4.211227419365753e-11 1.7547490763973973e-11 8454/8841/9734/23462/51564/55534/3280/6500/84441/10013/10046/7316/9978/9611/9759/9612/4609/10014/8850/1387/2033/55294/3066/3065/9794/6233/7311/388585/3516/4851/7314 31 Orf_virus R-HSA-68882 Mitotic Anaphase 68/1579 201/10654 8.364698877266011e-12 5.2572334489483484e-11 2.1906025536699698e-11 4000/5905/11130/84617/5903/10403/11065/55143/1058/991/79019/51807/10382/9212/3619/23244/7277/348995/79023/10381/57122/5705/7278/6232/332/7443/112714/1780/8881/5885/5528/7316/4085/23279/9861/79902/5519/5701/699/7846/113457/5698/347733/5708/22919/8243/9126/10376/5710/5702/7324/2010/11004/9232/5704/6233/9700/701/7514/7311/10383/5347/84790/55746/7112/5696/7280/7314 68 Orf_virus R-HSA-71291 Metabolism of amino acids and derivatives 105/1579 372/10654 9.322357024712927e-12 5.830955042861307e-11 2.4296628885258894e-11 6158/6470/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/3620/6217/3028/6222/6176/383/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/5705/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/9861/6130/6142/6167/6204/5701/6228/23521/116832/5698/5708/445/6192/6999/140801/6156/6235/6143/5710/6181/6124/5702/26227/6207/6139/6520/10295/5704/6233/7311/6223/25873/1738/4507/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/5696/6170/200916/6122/6133/6230 105 Orf_virus R-HSA-8986944 Transcriptional Regulation by MECP2 32/1579 62/10654 1.0554960241444598e-11 6.570336494793981e-11 2.7377509566073872e-11 818/27161/627/815/8841/5770/5468/817/9212/57690/27327/6657/192670/9611/28996/4233/9612/2289/5566/4988/4208/5728/816/192669/3066/3065/3654/23112/1385/25942/4343/26523 32 Orf_virus R-HSA-2555396 Mitotic Metaphase and Anaphase 68/1579 202/10654 1.0825582282626335e-11 6.706705976046125e-11 2.794573872457425e-11 4000/5905/11130/84617/5903/10403/11065/55143/1058/991/79019/51807/10382/9212/3619/23244/7277/348995/79023/10381/57122/5705/7278/6232/332/7443/112714/1780/8881/5885/5528/7316/4085/23279/9861/79902/5519/5701/699/7846/113457/5698/347733/5708/22919/8243/9126/10376/5710/5702/7324/2010/11004/9232/5704/6233/9700/701/7514/7311/10383/5347/84790/55746/7112/5696/7280/7314 68 Orf_virus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 19/1579 25/10654 1.1582268463785149e-11 7.14148401487416e-11 2.9757387173107266e-11 2308/2309/842/207/4303/84335/1027/7249/6199/1026/64223/2932/3164/79109/2475/1385/2931/253260/4193 19 Orf_virus R-HSA-180786 Extension of Telomeres 21/1579 30/10654 1.2768011068464916e-11 7.83546339626078e-11 3.264908490694852e-11 6118/2237/5982/54107/3978/5557/5422/5425/5111/5426/6119/5427/5985/5984/23649/5983/6117/5981/5558/5424/56655 21 Orf_virus R-HSA-391251 Protein folding 43/1579 101/10654 1.3013949787480335e-11 7.948896090850664e-11 3.3121740254768333e-11 2788/10694/84617/9134/8841/54331/2770/51807/10575/10382/1460/7277/10381/7278/112714/7203/10576/908/6774/1457/6950/7846/113457/347733/10376/55294/2783/2782/7157/2786/2771/10574/6468/10383/60/84790/22948/10693/7280/6904/2773/5201/2787 43 Orf_virus R-HSA-1980143 Signaling by NOTCH1 35/1579 73/10654 1.7570753809781287e-11 1.0682033040432455e-10 4.451027157913115e-11 8454/8841/9734/23462/51564/55534/3280/6500/409/84441/3091/10013/10046/7316/9978/9611/9759/9612/4609/10014/8850/1387/2033/408/55294/3066/3065/83737/9794/6233/7311/388585/3516/4851/7314 35 Orf_virus R-HSA-9022692 Regulation of MECP2 expression and activity 22/1579 33/10654 1.8682738360423813e-11 1.1305229119493665e-10 4.7107026955291375e-11 818/27161/815/8841/817/9212/57690/27327/192670/9611/28996/9612/5566/816/192669/3066/3065/23112/1385/25942/4343/26523 22 Orf_virus R-HSA-68877 Mitotic Prometaphase 67/1579 200/10654 1.970668046290473e-11 1.186962559362919e-10 4.9458774066256986e-11 5905/11130/84617/5903/10403/55143/64151/22981/7531/1058/991/203068/79019/54801/51807/10382/9212/3619/1460/23244/7277/348995/79023/9133/10381/57122/7278/6232/332/112714/1780/10051/5885/5528/891/4085/1457/983/1639/23279/79902/5566/5519/699/7846/113457/347733/3320/22919/8243/9126/10376/10426/23397/9918/10540/10733/1069/11004/701/7514/10383/5347/84790/55746/10592/7280 67 Orf_virus R-HSA-69275 G2/M Transition 66/1579 196/10654 2.1520819749266624e-11 1.290257442110409e-10 5.376290162926175e-11 8454/1017/84617/994/2305/22981/7531/203068/54801/51807/22974/10382/3161/6500/7277/9133/10381/5705/7278/112714/7316/728642/9978/891/993/890/983/1026/1639/6790/9861/5566/5519/5928/5701/23291/7846/113457/5698/347733/5708/3320/22919/2033/995/10376/10426/5710/5702/10540/7157/10733/8900/1069/5704/6233/3326/7514/7311/10383/5347/84790/7465/5696/7280/7314 66 Orf_virus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 36/1579 77/10654 2.2780699200789325e-11 1.359527048634262e-10 5.664925199616853e-11 84617/51807/10382/7277/9133/10381/5705/7278/112714/7316/891/983/1026/9861/5701/7846/113457/5698/347733/5708/3320/22919/10376/5710/5702/7157/5704/6233/3326/7311/10383/5347/84790/5696/7280/7314 36 Orf_virus R-HSA-168638 NOD1/2 Signaling Pathway 23/1579 36/10654 2.410126772468254e-11 1.4252613322641813e-10 5.938829128330865e-11 834/6885/842/835/841/7316/7128/1432/329/837/5603/83737/3654/7189/6233/7311/64170/5600/7334/1540/3551/6300/7314 23 Orf_virus R-HSA-6804757 Regulation of TP53 Degradation 23/1579 36/10654 2.410126772468254e-11 1.4252613322641813e-10 5.938829128330865e-11 1017/1029/207/11200/472/7316/890/983/64223/4194/5519/1616/9099/7157/8900/6233/79109/2475/7311/7874/7314/253260/4193 23 Orf_virus R-HSA-2500257 Resolution of Sister Chromatid Cohesion 49/1579 126/10654 2.646056157090319e-11 1.5577009322961564e-10 6.490683119321336e-11 5905/11130/84617/5903/10403/55143/1058/991/79019/51807/10382/9212/3619/23244/7277/348995/79023/9133/10381/57122/7278/6232/332/112714/1780/5885/5528/891/4085/983/23279/79902/5519/699/7846/113457/347733/22919/8243/9126/10376/11004/701/7514/10383/5347/84790/55746/7280 49 Orf_virus R-HSA-2467813 Separation of Sister Chromatids 64/1579 190/10654 4.275802499214711e-11 2.5057743475127654e-10 1.0441148824540427e-10 5905/11130/84617/5903/10403/11065/55143/1058/991/79019/51807/10382/9212/3619/23244/7277/348995/79023/10381/57122/5705/7278/6232/332/112714/1780/8881/5885/5528/7316/4085/23279/9861/79902/5519/5701/699/7846/113457/5698/347733/5708/22919/8243/9126/10376/5710/5702/7324/11004/9232/5704/6233/9700/701/7514/7311/10383/5347/84790/55746/5696/7280/7314 64 Orf_virus R-HSA-5673001 RAF/MAP kinase cascade 77/1579 249/10654 5.447874737253459e-11 3.178334095590471e-10 1.3243594475740056e-10 818/815/9462/6464/6711/1437/3667/1844/5604/3561/5747/3815/8844/817/84292/1439/5594/2322/409/3082/2064/5705/1438/2260/5528/7316/9978/1950/3560/2263/4233/3718/6714/5605/9861/6710/5519/2261/5701/5159/3558/3717/2247/8649/5698/5708/2335/2534/408/1445/5710/816/5702/1847/5979/5704/6233/2885/6709/3716/7311/5155/1956/60/4254/1843/3845/3265/3559/4763/5696/5245/7529/5156/7314/28956/5595 77 Orf_virus R-HSA-165159 mTOR signalling 24/1579 40/10654 6.084538065098627e-11 3.52346216087072e-10 1.468168625630827e-10 6194/389541/207/84335/7249/58528/6198/153129/64223/10325/8649/1981/6009/1977/10542/1975/2475/55004/10670/1978/64121/57521/7529/28956 24 Orf_virus R-HSA-69052 Switching of origins to a post-replicative state 39/1579 90/10654 6.093612499584258e-11 3.52346216087072e-10 1.468168625630827e-10 8454/1017/4172/9134/5000/11065/23594/6500/4173/5705/8881/7316/9978/4174/890/84515/4171/9861/4998/5701/6502/5698/5708/990/4175/5710/81620/5702/8900/7324/5704/6233/23595/7311/5001/5696/4999/4176/7314 39 Orf_virus R-HSA-2559580 Oxidative Stress Induced Senescence 48/1579 125/10654 7.128149819643498e-11 4.1034172191841554e-10 1.7098263423923622e-10 1912/3725/1019/5601/1029/2146/8535/6045/57690/5594/27327/80012/5931/192670/7316/1869/9261/1911/1871/7867/4194/5928/1432/84733/5602/23512/57332/192669/7157/23135/23112/5609/6233/2353/7311/4343/8726/5599/5600/23466/4217/26523/3456/6416/7314/6015/5595/4193 48 Orf_virus R-HSA-5693607 Processing of DNA double-strand break ends 41/1579 98/10654 7.585123184174802e-11 4.3472446090799196e-10 1.811425198168339e-10 1017/6118/54962/151987/9156/51588/5982/63967/5531/545/472/6613/7336/11073/7316/890/641/9656/6119/3364/7341/10524/5985/165918/84126/8914/1111/8900/5984/7329/6233/672/7311/6047/9025/5983/6117/7334/5884/5810/7314 41 Orf_virus R-HSA-70326 Glucose metabolism 39/1579 91/10654 9.158249416231946e-11 5.22582565373586e-10 2.1775154429175677e-10 23165/5903/2597/55706/7175/9631/5315/5567/5568/348995/79023/57122/23636/5214/10762/23511/5528/229/53371/5230/23279/4927/9688/79902/5566/5519/9883/2023/226/23225/2821/8086/5213/9972/8021/129401/2026/55746/8480 39 Orf_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 34/1579 73/10654 9.336037227401826e-11 5.304010669366714e-10 2.2100938506605101e-10 8454/57154/7291/10273/6500/5705/7316/9978/865/579/6772/2099/9861/2932/5701/6502/2908/5698/5708/2101/1749/55294/4488/5710/5702/5704/6233/7311/860/1750/133522/5696/10891/7314 34 Orf_virus R-HSA-674695 RNA Polymerase II Pre-transcription Events 37/1579 84/10654 1.0581245145711767e-10 5.9853043193787e-10 2.493977688806206e-10 2963/6917/5434/5440/2959/5430/6874/5436/9646/404672/6749/5441/5438/5431/5435/4686/5433/6872/2960/2966/2962/5437/2965/2068/5439/2071/2968/1025/23168/2967/6908/11198/2961/5432/22916/2957/25920 37 Orf_virus R-HSA-912526 Interleukin receptor SHC signaling 19/1579 27/10654 1.0762162398262488e-10 6.061287134259522e-10 2.525638475782721e-10 5295/5777/6464/5290/1437/3561/1439/1438/3560/3718/8503/3558/3717/3636/2885/3716/9846/5296/3559 19 Orf_virus R-HSA-176974 Unwinding of DNA 12/1579 12/10654 1.083745922061786e-10 6.077385537079239e-10 2.5323464149810335e-10 4172/8318/9837/64785/4173/4174/84515/4171/4175/84296/51659/4176 12 Orf_virus R-HSA-4420097 VEGFA-VEGFR2 Pathway 41/1579 99/10654 1.1118257191852726e-10 6.208091247467981e-10 2.5868093308353983e-10 5295/26999/5590/5290/5335/1499/5747/5567/207/7422/5568/3315/9047/9261/6714/7867/64223/5566/1432/3320/2534/4846/5603/79109/5580/2475/7409/23191/3685/3791/387/60/5296/3845/5600/3265/6300/5062/10787/5879/253260 41 Orf_virus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 42/1579 103/10654 1.191752068306694e-10 6.625937781482944e-10 2.7609190966169477e-10 5295/5290/3667/3815/207/5594/930/3082/941/2064/2260/4615/5528/2100/1950/2263/4233/6714/2099/5519/8503/2261/5159/2247/5880/2534/3630/942/3654/7189/2885/7409/3932/5155/1956/4254/5296/5781/5156/5879/5595/3556 42 Orf_virus R-HSA-73762 RNA Polymerase I Transcription Initiation 26/1579 47/10654 1.213064377474681e-10 6.715730872742809e-10 2.7983343982058714e-10 5434/5440/9112/9219/404672/5931/5441/5435/1108/2966/8850/5928/5437/57459/2965/54815/2068/3066/3065/2071/1107/2968/57504/2967/6908/53615 26 Orf_virus R-HSA-5663220 RHO GTPases Activate Formins 51/1579 140/10654 1.7295373990568106e-10 9.534441339715722e-10 3.97284460532675e-10 5905/11130/84617/5903/10403/55143/1058/991/79019/51807/10382/9212/3619/388/7277/348995/79023/10381/57122/7278/6232/332/112714/1780/5528/3688/4085/6714/23279/79902/5519/699/7846/113457/347733/22919/10376/11004/1855/701/1857/7514/23380/10383/5347/387/60/84790/55746/7280/5879 51 Orf_virus R-HSA-8848021 Signaling by PTK6 28/1579 54/10654 1.8044477253271382e-10 9.8638087842462465e-010 4.1100865924081207e-10 1017/1019/5770/207/9021/55620/27043/1027/3091/2064/10657/7316/1950/5753/6774/867/6421/2908/595/6233/7311/2034/387/1956/3845/3265/7314/5879 28 Orf_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 28/1579 54/10654 1.8044477253271382e-10 9.8638087842462465e-010 4.1100865924081207e-10 1017/1019/5770/207/9021/55620/27043/1027/3091/2064/10657/7316/1950/5753/6774/867/6421/2908/595/6233/7311/2034/387/1956/3845/3265/7314/5879 28 Orf_virus R-HSA-9006115 Signaling by NTRK2 (TRKB) 18/1579 25/10654 1.8490548678252734e-10 1.0065357251216237e-9 4.194068517639356e-10 5295/4908/627/6464/5290/5335/4915/7074/6714/4909/2534/2885/8851/3845/3265/1020/5781/5879 18 Orf_virus R-HSA-112382 Formation of RNA Pol II elongation complex 30/1579 61/10654 2.2170632397148155e-10 1.196846172144803e-9 4.987060792544791e-10 2963/6917/5434/5440/5430/5436/9646/404672/6749/5441/5438/5431/5435/4686/5433/2966/2962/5437/2965/2068/5439/2071/2968/1025/23168/2967/11198/5432/22916/25920 30 Orf_virus R-HSA-75955 RNA Polymerase II Transcription Elongation 30/1579 61/10654 2.2170632397148155e-10 1.196846172144803e-9 4.987060792544791e-10 2963/6917/5434/5440/5430/5436/9646/404672/6749/5441/5438/5431/5435/4686/5433/2966/2962/5437/2965/2068/5439/2071/2968/1025/23168/2967/11198/5432/22916/25920 30 Orf_virus R-HSA-73933 Resolution of Abasic Sites (AP sites) 23/1579 39/10654 2.50318940577541e-10 1.3457228995511607e-9 5.607405584925342e-10 6118/2237/328/5982/54107/3978/6996/5425/5111/5426/6119/5427/5985/142/5984/3980/5983/6117/5981/10038/5424/7374/56655 23 Orf_virus R-HSA-350054 Notch-HLH transcription pathway 19/1579 28/10654 2.8829108840130145e-10 1.5434843868728117e-9 6.431445117031417e-10 8841/9734/51564/55534/84441/10013/10046/4854/9611/9759/9612/10014/8850/1387/3066/3065/9794/3516/4851 19 Orf_virus R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 17/1579 23/10654 3.078140629687877e-10 1.6412544914852163e-9 6.838837033171944e-10 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/5439/5432/22916/25920 17 Orf_virus R-HSA-5621481 C-type lectin receptors (CLRs) 51/1579 142/10654 3.116664736685473e-10 1.6550125805827758e-9 6.896164723493098e-10 8454/4773/4790/6885/4772/5567/3553/5532/5568/4775/4582/6500/29108/5705/841/5530/7316/5970/4792/6850/6714/9861/5566/5701/1387/4067/23291/5698/5708/2534/2033/5710/5702/9040/7189/5704/6233/5580/7311/5971/64170/3845/7334/3265/3551/5062/5696/997/2207/4791/7314 51 Orf_virus R-HSA-199418 Negative regulation of the PI3K/AKT network 43/1579 110/10654 3.587106694017928e-10 1.897083662161514e-9 7.904835033886319e-10 5295/5290/3667/3815/207/5594/930/3082/941/2064/2260/4615/5528/2100/1950/2263/4233/6714/2099/5519/8503/2261/5159/2247/5880/2534/5728/3630/942/3654/7189/2885/7409/3932/5155/1956/4254/5296/5781/5156/5879/5595/3556 43 Orf_virus R-HSA-5688426 Deubiquitination 85/1579 297/10654 4.448097058622654e-10 2.342904564076143e-9 9.76249727334612e-10 23326/7186/6885/6314/991/8737/83444/171023/4738/7375/2625/57506/4303/57646/63967/409/6478/4086/1080/3091/5705/57695/11274/27005/7706/7316/993/79155/890/4792/983/8678/2099/1643/4609/7415/9861/4194/23586/4089/8850/7128/3416/5701/329/6502/7347/9099/4088/5698/5708/2033/408/64135/5728/5710/5702/7157/8900/9958/8975/4087/63891/7189/5704/6233/672/7048/7311/367/78990/7187/387/60/7040/5887/1540/29761/7874/154/5696/5886/7314/4193/7528 85 Orf_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 33/1579 73/10654 4.698867264631665e-10 2.465010609389434e-9 1.02712930445047e-9 57154/5590/6497/10273/4738/51592/3726/50848/54778/7316/9611/9612/6667/4609/4089/867/7050/4088/142/3065/9958/9040/4087/6233/7514/7048/1025/7311/25937/387/7040/57530/7314 33 Orf_virus R-HSA-5655253 Signaling by FGFR2 in disease 24/1579 43/10654 4.929640286104887e-10 2.575687555109421e-9 1.0732465640854014e-9 5295/2963/5434/5440/5290/5335/5430/5436/5441/5438/5431/5435/4686/5433/2263/2962/5437/2247/5439/2885/3845/3265/5432/22916 24 Orf_virus R-HSA-388841 Costimulation by the CD28 family 32/1579 70/10654 6.050670882785188e-10 3.1487691274014114e-9 1.3120402124776302e-9 5295/5777/5290/207/941/919/5528/920/6714/64223/5519/8503/29126/4067/915/917/2534/1445/916/942/2885/7525/79109/2475/7409/3932/5296/3127/5781/5062/5879/253260 32 Orf_virus R-HSA-1059683 Interleukin-6 signaling 11/1579 11/10654 7.356063678892622e-10 3.791448550893558e-9 1.579834138686988e-9 9021/6774/6772/867/3717/3716/3570/7297/5781/3569/3572 11 Orf_virus R-HSA-110320 Translesion Synthesis by POLH 15/1579 19/10654 7.402213158546994e-10 3.791448550893558e-9 1.579834138686988e-9 6118/5982/7316/5111/7415/6119/83932/5985/5984/6233/7311/5983/6117/5981/7314 15 Orf_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 15/1579 19/10654 7.402213158546994e-10 3.791448550893558e-9 1.579834138686988e-9 5295/6464/5290/5335/7316/1950/867/3320/6233/2885/7311/1956/3845/3265/7314 15 Orf_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 15/1579 19/10654 7.402213158546994e-10 3.791448550893558e-9 1.579834138686988e-9 5295/6464/5290/5335/7316/1950/867/3320/6233/2885/7311/1956/3845/3265/7314 15 Orf_virus R-HSA-8941326 RUNX2 regulates bone development 20/1579 32/10654 8.790562448157114e-10 4.484910488255845e-9 1.8687883016722035e-9 25/8841/23462/5594/3280/4086/5925/10013/865/4094/9759/10413/6714/4089/23314/7525/25937/367/860/5595 20 Orf_virus R-HSA-203927 MicroRNA (miRNA) biogenesis 17/1579 24/10654 9.093743468813365e-10 4.5856435088861194e-9 1.910762091570332e-9 27161/5434/5440/5430/5436/5441/192670/5438/5431/5435/5433/5437/5439/192669/26523/5432/23405 17 Orf_virus R-HSA-6783589 Interleukin-6 family signaling 17/1579 24/10654 9.093743468813365e-10 4.5856435088861194e-9 1.910762091570332e-9 3589/9021/3976/6774/6772/867/3717/3716/1270/3570/5008/3977/7297/5781/3569/1489/3572 17 Orf_virus R-HSA-8940973 RUNX2 regulates osteoblast differentiation 17/1579 24/10654 9.093743468813365e-10 4.5856435088861194e-9 1.910762091570332e-9 25/8841/23462/5594/3280/5925/10013/865/4094/10413/6714/23314/7525/25937/367/860/5595 17 Orf_virus R-HSA-5655862 Translesion synthesis by POLK 14/1579 17/10654 1.025722914872381e-9 5.1325596624960295e-9 2.138653041130673e-9 6118/5982/7316/5111/6119/5985/5984/6233/51426/7311/5983/6117/5981/7314 14 Orf_virus R-HSA-8934593 Regulation of RUNX1 Expression and Activity 14/1579 17/10654 1.025722914872381e-9 5.1325596624960295e-9 2.138653041130673e-9 27161/57690/27327/192670/865/6714/595/192669/861/5371/23112/4343/26523/5781 14 Orf_virus R-HSA-5357786 TNFR1-induced proapoptotic signaling 12/1579 13/10654 1.2173760102904545e-9 6.064404156606254e-9 2.5269372876347917e-9 7124/7186/8737/7375/841/27005/7128/7132/9099/8772/8717/1540 12 Orf_virus R-HSA-68867 Assembly of the pre-replicative complex 31/1579 68/10654 1.2212712444510674e-9 6.064404156606254e-9 2.5269372876347917e-9 4172/5000/23594/4173/5705/7316/1869/4174/84515/4171/1871/9861/51053/4998/5701/5698/5708/990/4175/5710/81620/5702/5704/6233/23595/7311/5001/5696/4999/4176/7314 31 Orf_virus R-HSA-1170546 Prolactin receptor signaling 13/1579 15/10654 1.2490545248955125e-9 6.1787830299964325e-9 2.5745970795324755e-9 8454/2690/6500/6776/9978/1442/3717/5618/2688/5617/6777/2689/5781 13 Orf_virus R-HSA-109581 Apoptosis 58/1579 178/10654 1.4864979168970462e-9 7.325506779860064e-9 3.052417971299756e-9 4000/3837/596/7186/1499/10018/7531/5747/1029/842/8737/356/207/5594/63967/5705/841/7099/100506658/9500/7316/1869/6774/54205/660/3146/9861/5701/329/999/598/836/5698/5708/5710/5702/7157/3836/5704/6233/5580/6709/7311/7161/839/840/1630/8772/5599/8717/7431/8795/5062/6304/5696/7529/7314/5595 58 Orf_virus R-HSA-113510 E2F mediated regulation of DNA replication 16/1579 22/10654 1.5530868563126854e-9 7.596112782190992e-9 3.1651750336408115e-9 5000/23594/5925/5557/5422/1869/891/983/84515/5519/4998/23595/23649/5001/5558/4999 16 Orf_virus R-HSA-912631 Regulation of signaling by CBL 16/1579 22/10654 1.5530868563126854e-9 7.596112782190992e-9 3.1651750336408115e-9 5295/5290/7316/3055/6850/8503/867/4067/2534/6233/2885/7525/7409/7311/5296/7314 16 Orf_virus R-HSA-194138 Signaling by VEGF 41/1579 107/10654 1.8668151901238064e-9 9.066798634863737e-9 3.777985595659067e-9 5295/26999/5590/5290/5335/1499/5747/5567/207/7422/5568/3315/9047/9261/6714/7867/64223/5566/1432/3320/2534/4846/5603/79109/5580/2475/7409/23191/3685/3791/387/60/5296/3845/5600/3265/6300/5062/10787/5879/253260 41 Orf_virus R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 27/1579 55/10654 1.867718704184075e-9 9.066798634863737e-9 3.777985595659067e-9 84617/5241/51807/10382/7277/10381/7278/112714/1780/1639/2289/7846/113457/2908/347733/3320/10376/10540/10963/3326/367/10383/84790/3312/7280/2288/10728 27 Orf_virus R-HSA-187037 Signaling by NTRK1 (TRKA) 34/1579 80/10654 1.9139660720273546e-9 9.256585173572529e-9 3.8570665191875494e-009 5295/6464/5290/3667/5335/4915/5604/5594/5528/6774/4205/9261/6714/5605/7867/5519/5598/1432/4208/4914/4803/5603/2002/2885/1385/6196/387/5296/3845/5600/3265/6300/7529/5595 34 Orf_virus R-HSA-389356 CD28 co-stimulation 20/1579 33/10654 1.9210438100419542e-9 9.256585173572529e-9 3.8570665191875494e-009 5295/5290/207/941/6714/64223/8503/4067/2534/942/2885/7525/79109/2475/7409/3932/5296/5062/5879/253260 20 Orf_virus R-HSA-383280 Nuclear Receptor transcription pathway 26/1579 52/10654 2.2523875963064714e-9 1.0813122740939923e-8 4.505650076122869e-9 6095/7068/5241/7182/5468/3172/2516/6097/5465/2100/4929/9611/5469/2063/9612/2099/7101/5467/2908/3164/2101/6256/7376/367/7421/10062 26 Orf_virus R-HSA-5357801 Programmed Cell Death 58/1579 181/10654 3.021013471525525e-9 1.4449773994318779e-8 6.020982731562095e-9 4000/3837/596/7186/1499/10018/7531/5747/1029/842/8737/356/207/5594/63967/5705/841/7099/100506658/9500/7316/1869/6774/54205/660/3146/9861/5701/329/999/598/836/5698/5708/5710/5702/7157/3836/5704/6233/5580/6709/7311/7161/839/840/1630/8772/5599/8717/7431/8795/5062/6304/5696/7529/7314/5595 58 Orf_virus R-HSA-429914 Deadenylation-dependent mRNA decay 27/1579 56/10654 3.100914453501123e-9 1.4777617963388135e-8 6.157589911521412e-9 1656/9924/80153/5073/27257/4849/4850/255967/26986/10605/9337/25904/246175/4848/23019/1981/1973/1977/1975/55571/9775/54464/57472/85456/29883/1974/167227 27 Orf_virus R-HSA-5687128 MAPK6/MAPK4 signaling 36/1579 89/10654 3.2711661011890225e-9 1.553206969944131e-8 6.4719575186797786e-9 2308/27161/2118/3725/2309/5567/57690/5568/3315/27327/5705/192670/7316/983/5597/4609/9861/5566/5701/5698/5708/5710/5702/192669/23112/5704/6233/7514/7311/4343/26523/8202/5062/5696/7314/5879 36 Orf_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 39/1579 101/10654 3.5743644064922125e-9 1.6909993064895884e-8 7.046115480740629e-9 8454/4773/4790/6885/4772/3553/5532/4775/6500/29108/5705/841/5530/7316/5970/4792/6850/6714/9861/5701/23291/5698/5708/5710/5702/9040/7189/5704/6233/5580/7311/5971/64170/7334/3551/5696/997/4791/7314 39 Orf_virus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 19/1579 31/10654 3.76134580675142e-9 1.7730111936897094e-8 7.387845501437763e-9 3725/5601/5594/5528/4205/9261/5519/5598/1432/4208/5602/2002/1385/2353/6196/1386/5599/5600/5595 19 Orf_virus R-HSA-190840 Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane 14/1579 18/10654 3.983308145158295e-9 1.8708606125815676e-8 7.795567907111995e-9 84617/51807/10382/7277/10381/7278/112714/7846/113457/347733/10376/10383/84790/7280 14 Orf_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 20/1579 34/10654 4.016637535616944e-9 1.8797285733228933e-8 7.832519238329141e-9 29110/57506/9636/7706/7316/3093/23586/7128/64135/83737/3661/9246/51191/6233/7311/5094/7187/5300/1540/7314 20 Orf_virus R-HSA-110056 MAPK3 (ERK1) activation 10/1579 10/10654 4.99030859134052e-9 2.3022664813241196e-8 9.59316507853814e-9 5604/983/3717/3716/3570/7297/5781/3569/3572/5595 10 Orf_virus R-HSA-390450 Folding of actin by CCT/TriC 10/1579 10/10654 4.99030859134052e-9 2.3022664813241196e-8 9.59316507853814e-9 10694/10575/7203/10576/908/6950/10574/60/22948/10693 10 Orf_virus R-HSA-450341 Activation of the AP-1 family of transcription factors 10/1579 10/10654 4.99030859134052e-9 2.3022664813241196e-8 9.59316507853814e-9 3725/5601/5594/1432/5602/2353/1386/5599/5600/5595 10 Orf_virus R-HSA-9020958 Interleukin-21 signaling 10/1579 10/10654 4.99030859134052e-9 2.3022664813241196e-8 9.59316507853814e-9 3561/6775/6776/50615/6774/3718/6772/3716/6777/59067 10 Orf_virus R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 32/1579 75/10654 5.082936753025468e-9 2.3367140338113548e-8 9.736702353759033e-9 5295/5290/3667/3815/930/3082/941/2064/2260/2100/1950/2263/4233/6714/2099/8503/2261/5159/2247/5880/2534/942/2885/7409/3932/5155/1956/4254/5296/5781/5156/5879 32 Orf_virus R-HSA-9020591 Interleukin-12 signaling 24/1579 47/10654 5.435690564643985e-9 2.490082191761206e-8 1.0375762197152158e-8 1072/3592/27250/3593/6775/3595/1265/4478/3313/6175/6647/6950/3717/3458/3181/6648/3716/3594/2939/4507/302/7297/5062/3586 24 Orf_virus R-HSA-110312 Translesion synthesis by REV1 13/1579 16/10654 5.752615574259526e-9 2.6168366650740014e-8 1.090392720185372e-8 6118/5982/7316/5111/6119/5985/5984/6233/7311/5983/6117/5981/7314 13 Orf_virus R-HSA-1433559 Regulation of KIT signaling 13/1579 16/10654 5.752615574259526e-9 2.6168366650740014e-8 1.090392720185372e-8 5777/3815/9306/6714/8651/867/4067/2534/2885/7525/3932/4254/10603 13 Orf_virus R-HSA-9020702 Interleukin-1 signaling 39/1579 103/10654 6.87135640493165e-9 3.114855290179818e-8 1.2979088753125986e-8 8454/3557/351/4790/6885/5604/3553/6500/5705/4615/7316/9978/79155/5970/4792/3146/9861/3552/5701/23291/5698/5708/5710/6288/5702/3654/7189/5704/6233/7311/7334/3551/7850/6416/5696/4791/3554/7314/3556 39 Orf_virus R-HSA-174411 Polymerase switching on the C-strand of the telomere 12/1579 14/10654 7.364355865569855e-9 3.292449134400818e-8 1.3719093039495299e-8 5982/5557/5422/5425/5111/5985/5984/23649/5983/5981/5558/5424 12 Orf_virus R-HSA-69091 Polymerase switching 12/1579 14/10654 7.364355865569855e-9 3.292449134400818e-8 1.3719093039495299e-8 5982/5557/5422/5425/5111/5985/5984/23649/5983/5981/5558/5424 12 Orf_virus R-HSA-69109 Leading Strand Synthesis 12/1579 14/10654 7.364355865569855e-9 3.292449134400818e-8 1.3719093039495299e-8 5982/5557/5422/5425/5111/5985/5984/23649/5983/5981/5558/5424 12 Orf_virus R-HSA-8983432 Interleukin-15 signaling 12/1579 14/10654 7.364355865569855e-9 3.292449134400818e-8 1.3719093039495299e-8 6464/3561/6776/3560/6774/3718/2885/3716/9846/6777/3600/3601 12 Orf_virus R-HSA-3371511 HSF1 activation 11/1579 12/10654 7.635155900403132e-9 3.374595691028474e-8 1.4061384205507212e-8 6118/7531/1915/10013/7415/6119/3320/3326/6117/3297/10728 11 Orf_virus R-HSA-8984722 Interleukin-35 Signalling 11/1579 12/10654 7.635155900403132e-9 3.374595691028474e-8 1.4061384205507212e-8 10148/3592/6775/3595/6774/6772/3717/9466/3716/7297/3572 11 Orf_virus R-HSA-9020558 Interleukin-2 signaling 11/1579 12/10654 7.635155900403132e-9 3.374595691028474e-8 1.4061384205507212e-8 6464/3561/6776/3560/6850/3718/3558/3716/3932/6777/3559 11 Orf_virus R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 15/1579 21/10654 7.709673854142165e-9 3.374595691028474e-8 1.4061384205507212e-8 7832/4849/4869/4850/9337/25904/246175/4848/23019/995/7157/55571/57472/85456/29883 15 Orf_virus R-HSA-9614085 FOXO-mediated transcription 29/1579 65/10654 7.714473807416142e-9 3.374595691028474e-8 1.4061384205507212e-8 2308/2309/65018/10018/356/207/4303/1027/1649/4800/5443/1026/4089/8850/1647/1387/4088/2908/2033/3630/3066/3065/6648/4087/604/23411/25942/7529/10891 29 Orf_virus R-HSA-5655302 Signaling by FGFR1 in disease 21/1579 38/10654 7.729665764231248e-9 3.374595691028474e-8 1.4061384205507212e-8 5295/8805/11052/26127/5290/5335/613/2260/9208/6776/6774/6772/399687/2247/2885/9846/3845/6777/3265/7750/1523 21 Orf_virus R-HSA-5696394 DNA Damage Recognition in GG-NER 21/1579 38/10654 7.729665764231248e-9 3.374595691028474e-8 1.4061384205507212e-8 9318/83444/8450/7316/9978/1643/10980/1642/142/10987/1069/6233/7311/60/5887/10038/5886/7508/7314/8451/7528 21 Orf_virus R-HSA-983231 Factors involved in megakaryocyte development and platelet production 54/1579 168/10654 9.365107805688299e-9 4.074918145551999e-8 1.697951247994886e-8 55582/1017/84617/25/2624/23186/5567/51807/23095/10382/2625/5568/29127/3832/7277/10381/7278/112714/23303/285643/3659/5566/23414/10112/3705/3717/7846/5576/113457/347733/10376/3066/3065/7157/23028/3439/11004/10749/10383/24137/51317/60/25942/84790/9493/7465/3456/1020/81704/10603/7280/3660/9732/5879 54 Orf_virus R-HSA-76002 Platelet activation, signaling and aggregation 74/1579 262/10654 1.133097230234273e-8 4.913864988449297e-8 2.0475265739321073e-8 5295/2788/928/5777/5590/351/1072/6464/5321/5290/54331/7018/5770/7042/5747/2770/2316/207/7422/5594/409/3082/388/7277/83706/334/1950/335/308/6850/2767/6714/6647/8503/4352/1432/226/4067/81/5880/2335/2534/408/2783/1445/2782/87/2786/2771/10487/2885/5580/7409/8407/3932/7076/3479/5155/387/5296/5581/51368/7040/213/5781/7043/2207/2773/967/5879/5595/2787/7066/10672 74 Orf_virus R-HSA-3371571 HSF1-dependent transactivation 16/1579 24/10654 1.1379525315247873e-8 4.918525725959296e-8 2.0494686264566025e-8 818/815/817/84335/64223/1387/3320/2033/816/3326/2475/3312/3297/57521/2288/10728 16 Orf_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 34/1579 85/10654 1.2515000162334329e-8 5.3913957652970074e-8 2.246505780272631e-8 8454/1017/9134/1019/994/207/1027/6500/5925/5705/4149/7316/1869/5753/993/890/1026/4609/9861/5928/5701/6502/5698/5708/595/5710/5702/8900/5704/6233/7311/7465/5696/7314 34 Orf_virus R-HSA-190872 Transport of connexons to the plasma membrane 14/1579 19/10654 1.3063951267208358e-8 5.60930712826339e-8 2.337305854650792e-8 84617/51807/10382/7277/10381/7278/112714/7846/113457/347733/10376/10383/84790/7280 14 Orf_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 28/1579 63/10654 1.550957952660897e-8 6.637487817144167e-8 2.765731806164688e-8 3665/5434/5440/4790/1499/8737/29110/5441/6778/4615/7098/9208/5591/5435/7316/5970/4792/1387/5437/2033/1660/3661/6233/7311/3551/2547/4791/7314 28 Orf_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 18/1579 30/10654 1.5783264723748967e-8 6.732468001835215e-8 2.8053084841175903e-8 7124/7186/6885/8737/7375/27005/7316/7128/7132/329/9099/6233/7311/8717/1540/3551/7185/7314 18 Orf_virus R-HSA-5578749 Transcriptional regulation by small RNAs 39/1579 106/10654 1.7537879260405945e-8 7.456464352218345e-8 3.106985833886846e-8 23165/27161/5434/5440/5903/55706/7175/9631/5430/5436/27327/348995/79023/57122/5441/23636/5438/10762/5431/23511/5435/5433/53371/23279/4927/9688/79902/9883/5437/23225/5439/8086/9972/8021/129401/26523/5432/55746/8480 39 Orf_virus R-HSA-211000 Gene Silencing by RNA 46/1579 136/10654 2.0213489942889162e-8 8.566042480683647e-8 3.569328757273416e-8 23165/27161/5434/5440/5903/55706/7175/9631/5430/5436/57690/27327/348995/79023/57122/5441/23636/192670/5438/10762/5431/23511/5435/5433/53371/23279/4927/9688/79902/9883/5437/23225/3320/5439/192669/8086/23112/9972/8021/7257/129401/26523/5432/55746/23405/8480 46 Orf_virus R-HSA-389977 Post-chaperonin tubulin folding pathway 15/1579 22/10654 2.0902360278062586e-8 8.772248619922393e-8 3.655251457793628e-8 84617/51807/10382/7277/10381/7278/112714/7846/113457/347733/10376/10383/84790/7280/6904 15 Orf_virus R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 15/1579 22/10654 2.0902360278062586e-8 8.772248619922393e-8 3.655251457793628e-8 4000/3725/826/351/994/2309/10018/7531/356/823/993/995/6648/8851/1020 15 Orf_virus R-HSA-8863678 Neurodegenerative Diseases 15/1579 22/10654 2.0902360278062586e-8 8.772248619922393e-8 3.655251457793628e-8 4000/3725/826/351/994/2309/10018/7531/356/823/993/995/6648/8851/1020 15 Orf_virus R-HSA-5656121 Translesion synthesis by POLI 13/1579 17/10654 2.1115016717267645e-8 8.833002170149583e-8 3.680566461124669e-8 6118/5982/7316/5111/6119/5985/5984/6233/7311/5983/6117/5981/7314 13 Orf_virus R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 31/1579 75/10654 2.1907683331935478e-8 9.13522308168207e-8 3.806496935204713e-8 23165/5903/55706/7175/9631/6428/348995/79023/57122/23636/10762/23511/4686/53371/11338/23279/4927/9688/79902/9883/23225/10189/10482/8086/9972/8021/9775/129401/55746/22916/8480 31 Orf_virus R-HSA-69202 Cyclin E associated events during G1/S transition 33/1579 83/10654 2.4413101404830094e-8 1.0147426494467715e-7 4.2282654190306027e-8 8454/1017/9134/1019/207/1027/6500/5925/5705/4149/7316/1869/5753/993/890/1026/4609/9861/5928/5701/6502/5698/5708/595/5710/5702/8900/5704/6233/7311/7465/5696/7314 33 Orf_virus R-HSA-1227986 Signaling by ERBB2 24/1579 50/10654 2.608944210226765e-8 1.0809670119442743e-7 4.504211425634542e-8 5295/6464/5290/5335/10273/207/2064/7316/1950/5753/6714/3320/2534/6233/2885/7525/5580/7311/387/1956/5581/3845/3265/7314 24 Orf_virus R-HSA-5685938 HDR through Single Strand Annealing (SSA) 20/1579 37/10654 2.929878171417482e-8 1.210086190798141e-7 5.042229768688398e-8 6118/25/5888/9156/5982/545/472/11073/641/6119/3364/10524/5985/84126/5984/672/5983/6117/5884/5810 20 Orf_virus R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 19/1579 34/10654 3.1606293151548305e-8 1.2971541763458784e-7 5.405027718096423e-8 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/5435/5433/2962/5437/5439/1025/11198/5432/25920 19 Orf_virus R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 19/1579 34/10654 3.1606293151548305e-8 1.2971541763458784e-7 5.405027718096423e-8 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/5435/5433/2962/5437/5439/1025/11198/5432/25920 19 Orf_virus R-HSA-69183 Processive synthesis on the lagging strand 12/1579 15/10654 3.1825561228267384e-8 1.3020457596847758e-7 5.4254101398734526e-8 6118/2237/3978/5557/5422/5425/5111/6119/23649/6117/5558/5424 12 Orf_virus R-HSA-1839124 FGFR1 mutant receptor activation 18/1579 31/10654 3.2428998608822287e-8 1.3225745200651346e-7 5.51095010181273e-8 5295/8805/11052/26127/5290/613/2260/9208/6776/6774/6772/399687/2247/2885/9846/6777/7750/1523 18 Orf_virus R-HSA-72202 Transport of Mature Transcript to Cytoplasm 33/1579 84/10654 3.455512447974781e-8 1.4048817796297467e-7 5.853910890483593e-8 23165/5903/55706/7175/9631/7884/6428/348995/79023/57122/23636/10762/23511/4686/53371/11338/23279/4927/9688/79902/9883/23225/10189/10482/8086/1977/9972/8021/9775/129401/55746/22916/8480 33 Orf_virus R-HSA-157118 Signaling by NOTCH 67/1579 235/10654 3.757333913437825e-8 1.5186874783631118e-7 6.328120485108642e-8 8454/27161/3725/8841/2208/9734/23462/207/51564/55534/57690/3280/6500/27327/409/84441/3091/10013/5705/10046/192670/7316/9978/1950/1869/4854/9611/9759/9612/6772/4609/1871/9861/10014/8850/5701/1387/4088/5698/5708/2033/408/595/55294/5710/5702/192669/3066/3065/7157/83737/861/23112/9794/5704/6233/1385/7311/1956/4343/9787/388585/26523/3516/4851/5696/7314 67 Orf_virus R-HSA-3232118 SUMOylation of transcription factors 14/1579 20/10654 3.758780692028609e-8 1.5186874783631118e-7 6.328120485108642e-8 7020/1029/9112/51588/3090/6613/7341/10401/7157/7329/6612/9063/4193/8554 14 Orf_virus R-HSA-209560 NF-kB is activated and signals survival 11/1579 13/10654 4.293294529602315e-8 1.7292805520162885e-7 7.205627123171556e-8 4790/7316/5970/4792/4803/3654/7189/6233/7311/3551/7314 11 Orf_virus R-HSA-2514853 Condensation of Prometaphase Chromosomes 10/1579 11/10654 4.753733082585308e-8 1.9029559201364573e-7 7.929303765283993e-8 64151/1460/9133/10051/891/1457/983/23397/9918/10592 10 Orf_virus R-HSA-68689 CDC6 association with the ORC:origin complex 10/1579 11/10654 4.753733082585308e-8 1.9029559201364573e-7 7.929303765283993e-8 5000/23594/1869/84515/1871/4998/990/23595/5001/4999 10 Orf_virus R-HSA-112409 RAF-independent MAPK1/3 activation 15/1579 23/10654 5.1845364543798324e-8 2.062716185672221e-7 8.594998467747026e-8 1844/5604/5594/983/5605/3717/1847/3716/1843/3570/7297/5781/3569/3572/5595 15 Orf_virus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 15/1579 23/10654 5.1845364543798324e-8 2.062716185672221e-7 8.594998467747026e-8 6497/51592/54778/7316/9611/9612/4089/7050/4088/142/3065/4087/6233/7311/7314 15 Orf_virus R-HSA-5689896 Ovarian tumor domain proteases 20/1579 38/10654 5.326446610300125e-8 2.1127155609757506e-7 8.803337626137882e-8 8737/57506/7706/7316/79155/983/2099/7415/23586/7128/64135/5728/7157/7189/6233/7311/78990/7187/387/7314 20 Orf_virus R-HSA-5626467 RHO GTPases activate IQGAPs 18/1579 32/10654 6.387123885883637e-8 2.5257289287339245e-7 1.0524296276531988e-7 84617/1499/51807/10382/7277/10381/7278/112714/7846/999/113457/347733/10376/10383/60/84790/7280/5879 18 Orf_virus R-HSA-186763 Downstream signal transduction 17/1579 29/10654 6.484377685211539e-8 2.5564167783212763e-7 1.0652167489262974e-7 5295/5290/5335/6778/6776/6774/6772/6714/5159/2885/5155/5296/3845/6777/3265/5781/5156 17 Orf_virus R-HSA-5628897 TP53 Regulates Metabolic Genes 33/1579 86/10654 6.769283080011111e-8 2.660675917551195e-7 1.1086598143443225e-7 27161/7531/389541/207/57690/7249/27327/58528/192670/153129/54205/64223/10325/2821/8649/10128/5728/6009/192669/7157/23112/10542/2475/55004/10670/4513/4343/50484/26523/64121/57521/7529/28956 33 Orf_virus R-HSA-73887 Death Receptor Signalling 46/1579 141/10654 7.043952696868276e-8 2.7602959212727794e-7 1.1501698284360058e-7 7124/8841/7186/4790/6885/10018/7531/8737/356/7375/835/7074/841/27005/4615/9500/7316/5970/4792/7128/7132/329/9099/843/836/396/4803/11108/3066/3065/3654/7189/6233/7409/7311/387/8772/5599/8717/1540/3551/7185/8795/7314/5879/10672 46 Orf_virus R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 20/1579 39/10654 9.415693096916553e-8 3.6786236393658964e-7 1.5328218570924683e-7 6118/5888/9156/5982/545/472/11073/641/6119/3364/10524/5985/84126/1111/5984/672/5983/6117/5884/5810 20 Orf_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 39/1579 112/10654 9.90460957272129e-8 3.8580530102126935e-7 1.6075871194300234e-7 5295/8454/5777/4773/4790/6885/5966/4772/640/5532/4775/6500/930/5705/5530/7316/5970/4792/6850/9861/5701/4067/23291/5698/5708/2534/5710/5702/695/5704/6233/2885/7409/7311/3845/3265/3551/5696/7314 39 Orf_virus R-HSA-1266695 Interleukin-7 signaling 19/1579 36/10654 1.0864711991256413e-7 4.1943591396512146e-7 1.7477203421824308e-7 5295/54014/3667/6597/64109/3561/3082/6776/6774/3718/8651/8503/3716/85480/1154/3575/5296/8835/6777 19 Orf_virus R-HSA-167287 HIV elongation arrest and recovery 19/1579 36/10654 1.0864711991256413e-7 4.1943591396512146e-7 1.7477203421824308e-7 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/5435/5433/2962/5437/5439/1025/11198/5432/25920 19 Orf_virus R-HSA-167290 Pausing and recovery of HIV elongation 19/1579 36/10654 1.0864711991256413e-7 4.1943591396512146e-7 1.7477203421824308e-7 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/5435/5433/2962/5437/5439/1025/11198/5432/25920 19 Orf_virus R-HSA-1295596 Spry regulation of FGF signaling 12/1579 16/10654 1.1004439819029106e-7 4.198468095177967e-7 1.749432476246331e-7 10253/5594/7316/6714/8569/867/6233/2885/7311/5781/7314/5595 12 Orf_virus R-HSA-193639 p75NTR signals via NF-kB 12/1579 16/10654 1.1004439819029106e-7 4.198468095177967e-7 1.749432476246331e-7 4790/4615/7316/5970/4792/4803/3654/7189/6233/7311/3551/7314 12 Orf_virus R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 12/1579 16/10654 1.1004439819029106e-7 4.198468095177967e-7 1.749432476246331e-7 5295/6464/5290/2205/2206/6850/4067/2534/2885/9846/5296/2207 12 Orf_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 12/1579 16/10654 1.1004439819029106e-7 4.198468095177967e-7 1.749432476246331e-7 8454/4790/5604/6500/7316/79155/23291/6233/7311/3551/6416/7314 12 Orf_virus R-HSA-933542 TRAF6 mediated NF-kB activation 15/1579 24/10654 1.1928842992471616e-7 4.537843489241396e-7 1.890844610995039e-7 351/7186/4790/57506/4214/7706/5970/4792/3146/23586/64135/6288/7189/3551/4791 15 Orf_virus R-HSA-1839126 FGFR2 mutant receptor activation 18/1579 33/10654 1.2109047217944194e-7 4.5796134972515685e-7 1.908249485079945e-7 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2263/2962/5437/2247/5439/5432/22916 18 Orf_virus R-HSA-5357905 Regulation of TNFR1 signaling 18/1579 33/10654 1.2109047217944194e-7 4.5796134972515685e-7 1.908249485079945e-7 7124/7186/8737/7375/841/27005/7316/7128/7132/329/9099/6233/7311/8717/1540/3551/7185/7314 18 Orf_virus R-HSA-6784531 tRNA processing in the nucleus 25/1579 57/10654 1.2560558548481752e-7 4.73660483234051e-7 1.973665187633288e-7 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/283742/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 25 Orf_virus R-HSA-195258 RHO GTPase Effectors 84/1579 327/10654 1.327419495531097e-7 4.991250762098142e-7 2.0797719507104195e-7 26999/5905/11130/84617/25/5590/5903/1072/10403/51517/55143/1499/7531/5747/1058/991/79019/51807/2316/10382/9212/5594/1027/3619/388/1080/7277/348995/79023/10381/57122/7278/6232/332/112714/1780/6242/5528/3688/4085/5585/6714/23279/79902/5519/1432/2017/699/7846/999/113457/347733/5880/22919/995/10376/23028/695/11004/1855/2885/5580/701/1857/9055/23191/7514/23380/57120/367/10383/5347/387/60/5300/84790/5600/5062/55746/7280/7529/10787/5879/5595 84 Orf_virus R-HSA-5654741 Signaling by FGFR3 20/1579 40/10654 1.6218596682074994e-7 6.080805268985466e-7 2.533771360918739e-7 5295/10253/6464/5290/5335/5594/7316/6714/8569/2261/867/2247/6233/2885/7311/3845/3265/5781/7314/5595 20 Orf_virus R-HSA-69166 Removal of the Flap Intermediate 11/1579 14/10654 1.733511065410178e-7 6.462171622059145e-7 2.69268043639343e-7 6118/2237/5557/5422/5425/5111/6119/23649/6117/5558/5424 11 Orf_virus R-HSA-918233 TRAF3-dependent IRF activation pathway 11/1579 14/10654 1.733511065410178e-7 6.462171622059145e-7 2.69268043639343e-7 3665/29110/57506/7706/23586/1387/2033/64135/3661/7187/3456 11 Orf_virus R-HSA-438064 Post NMDA receptor activation events 31/1579 81/10654 1.8048858005153545e-7 6.709018361344218e-7 2.7955374053094963e-7 818/84617/815/3838/5567/51807/817/10382/5594/5568/7277/10381/7278/112714/6714/5566/7846/5576/113457/347733/10376/816/1385/6196/10383/84790/3845/3265/7280/5879/5595 31 Orf_virus R-HSA-5689880 Ub-specific processing proteases 62/1579 220/10654 1.9090640600193533e-7 7.076046558647232e-7 2.9484720075272666e-7 23326/7186/6885/6314/991/8737/7375/2625/4303/57646/63967/409/6478/4086/1080/3091/5705/57695/11274/27005/7316/993/890/4792/8678/1643/4609/9861/4194/23586/4089/3416/5701/329/6502/9099/4088/5698/5708/408/64135/5728/5710/5702/7157/8900/9958/8975/4087/63891/7189/5704/6233/7311/367/1540/29761/7874/154/5696/7314/4193 62 Orf_virus R-HSA-202424 Downstream TCR signaling 35/1579 98/10654 2.1965740306666313e-7 8.089397341931063e-7 3.3707185817342915e-7 5295/8454/5290/4790/6885/6500/5705/919/7316/920/5970/4792/9861/5701/23291/915/917/5698/5708/5728/5710/916/5702/7189/5704/6233/7311/3932/5296/3127/7334/3551/5696/997/7314 35 Orf_virus R-HSA-69231 Cyclin D associated events in G1 21/1579 44/10654 2.201111959295616e-7 8.089397341931063e-7 3.3707185817342915e-7 8454/25/1019/1029/1027/6500/5925/7316/1869/5753/1026/6714/1871/5519/4067/3717/6502/595/6233/7311/7314 21 Orf_virus R-HSA-69236 G1 Phase 21/1579 44/10654 2.201111959295616e-7 8.089397341931063e-7 3.3707185817342915e-7 8454/25/1019/1029/1027/6500/5925/7316/1869/5753/1026/6714/1871/5519/4067/3717/6502/595/6233/7311/7314 21 Orf_virus R-HSA-187687 Signalling to ERKs 18/1579 34/10654 2.217601735858222e-7 8.127041854511399e-7 3.3864044298502127e-7 6464/5604/5594/9261/6714/5605/7867/1432/4914/4803/5603/2885/3845/5600/3265/6300/7529/5595 18 Orf_virus R-HSA-2197563 NOTCH2 intracellular domain regulates transcription 10/1579 12/10654 2.470482054531025e-7 9.028362789170966e-7 3.7619700120741515e-7 2208/55534/3280/84441/10046/2033/9794/1385/388585/3516 10 Orf_virus R-HSA-9013694 Signaling by NOTCH4 31/1579 82/10654 2.494738358407035e-7 9.091469479797066e-7 3.7882655302362465e-7 8454/23462/207/55534/3280/6500/84441/5705/10046/7316/9978/9861/8850/5701/1387/4088/5698/5708/2033/55294/5710/5702/9794/5704/6233/7311/388585/3516/4851/5696/7314 31 Orf_virus R-HSA-1643713 Signaling by EGFR in Cancer 15/1579 25/10654 2.5733670779716724e-7 9.325767600114612e-7 3.8858936963946964e-7 5295/6464/5290/5335/7316/1950/867/3320/6233/2885/7311/1956/3845/3265/7314 15 Orf_virus R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 15/1579 25/10654 2.5733670779716724e-7 9.325767600114612e-7 3.8858936963946964e-7 23462/55534/3280/84441/10046/4854/6772/8850/1387/2033/9794/9787/388585/3516/4851 15 Orf_virus R-HSA-983189 Kinesins 25/1579 59/10654 2.8356498412341107e-7 1.0247723454015494e-6 4.2700575094607217e-7 55582/84617/51807/23095/10382/29127/3832/7277/10381/7278/112714/23303/285643/10112/7846/113457/347733/10376/11004/10749/10383/24137/84790/9493/7280 25 Orf_virus R-HSA-3215018 Processing and activation of SUMO 9/1579 10/10654 2.934428593328394e-7 1.057532299146881e-6 4.406562838793185e-7 10054/29843/6613/7341/10055/59343/7329/6612/205564 9 Orf_virus R-HSA-69473 G2/M DNA damage checkpoint 34/1579 95/10654 3.0801631784572424e-7 1.1069868218709592e-6 4.612631686261936e-7 6118/9156/7531/51588/5982/11200/545/472/7336/11073/891/983/641/9656/6119/3364/7341/10524/5985/995/165918/84126/1111/7157/5984/672/9025/5983/6117/7334/7465/5884/5810/7529 34 Orf_virus R-HSA-4655427 SUMOylation of DNA methylation proteins 12/1579 17/10654 3.234749137255476e-7 1.156156216365213e-6 4.817512451378168e-7 1912/8535/1786/6045/80012/1911/7341/84733/57332/7329/7703/6015 12 Orf_virus R-HSA-9034015 Signaling by NTRK3 (TRKC) 12/1579 17/10654 3.234749137255476e-7 1.156156216365213e-6 4.817512451378168e-7 5295/4908/6464/5290/3667/5335/6714/2885/3845/3265/4916/25920 12 Orf_virus R-HSA-72165 mRNA Splicing - Minor Pathway 23/1579 52/10654 3.320297169651197e-7 1.183481265127728e-6 4.931371427167603e-7 23451/2963/5434/5440/6632/5430/5436/23450/5441/5438/5431/5435/4686/5433/9343/2962/5437/5439/6634/5432/22916/10992/6628 23 Orf_virus R-HSA-8953750 Transcriptional Regulation by E2F6 18/1579 35/10654 3.9350533837685826e-7 1.3987717082740235e-6 5.828451229913201e-7 5888/2146/8317/6045/80012/5931/4149/1869/1911/5928/10138/23512/1111/672/8726/7703/6015/6241 18 Orf_virus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 25/1579 60/10654 4.1825686456148167e-7 1.4827034899032362e-6 6.178181134351443e-7 8454/1017/9134/1019/1027/6500/5705/7316/5753/890/1026/9861/5701/6502/5698/5708/595/5710/5702/8900/5704/6233/7311/5696/7314 25 Orf_virus R-HSA-167044 Signalling to RAS 13/1579 20/10654 4.4336567029879764e-7 1.5631944093732676e-6 6.513573533130246e-7 6464/9261/6714/7867/1432/4914/4803/5603/2885/3845/5600/3265/6300 13 Orf_virus R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 13/1579 20/10654 4.4336567029879764e-7 1.5631944093732676e-6 6.513573533130246e-7 23462/55534/3280/84441/10046/8850/1387/4088/2033/9794/388585/3516/4851 13 Orf_virus R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 20/1579 42/10654 4.4848739036892025e-7 1.5727280185174266e-6 6.553298511561752e-7 6118/5888/9156/5982/545/472/11073/641/6119/3364/10524/5985/84126/1111/5984/672/5983/6117/5884/5810 20 Orf_virus R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 20/1579 42/10654 4.4848739036892025e-7 1.5727280185174266e-6 6.553298511561752e-7 2788/10694/54331/2770/10575/1460/7203/10576/908/1457/6950/2783/2782/2786/2771/10574/22948/10693/2773/2787 20 Orf_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 32/1579 88/10654 4.5104986531618273e-7 1.5774620289686928e-6 6.57302435307963e-7 5073/207/3184/3315/26986/5705/7316/9261/9861/1432/5701/5698/5708/1981/5710/5702/5704/6233/5580/7514/7311/8021/54464/5600/3312/8570/6418/5696/167227/7529/7314/1994 32 Orf_virus R-HSA-69615 G1/S DNA Damage Checkpoints 27/1579 68/10654 4.677609451093712e-7 1.6315200793224985e-6 6.798275341648828e-7 1017/9134/1029/1027/11200/472/5705/7316/993/890/1026/9861/4194/5701/5698/5708/5710/1111/5702/7157/8900/5704/6233/7311/5696/7314/4193 27 Orf_virus R-HSA-5637810 Constitutive Signaling by EGFRvIII 11/1579 15/10654 5.625463561510804e-7 1.9464702376397757e-6 8.110620756377559e-7 5295/6464/5290/5335/1950/867/3320/2885/1956/3845/3265 11 Orf_virus R-HSA-5637812 Signaling by EGFRvIII in Cancer 11/1579 15/10654 5.625463561510804e-7 1.9464702376397757e-6 8.110620756377559e-7 5295/6464/5290/5335/1950/867/3320/2885/1956/3845/3265 11 Orf_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 11/1579 15/10654 5.625463561510804e-7 1.9464702376397757e-6 8.110620756377559e-7 54106/3665/4615/7316/3654/7189/6233/51311/7311/7334/7314 11 Orf_virus R-HSA-202403 TCR signaling 39/1579 119/10654 6.033958152169829e-7 2.0767670782997217e-6 8.653546222131613e-7 5295/8454/5290/5335/4790/6885/6500/5705/5788/919/7316/920/5970/4792/9861/5701/23291/915/917/5698/5708/5728/1445/5710/916/5702/7189/5704/6233/7311/3932/5296/3127/7334/3551/5062/5696/997/7314 39 Orf_virus R-HSA-373760 L1CAM interactions 39/1579 119/10654 6.033958152169829e-7 2.0767670782997217e-6 8.653546222131613e-7 84617/6711/5604/51807/10382/5594/1460/7277/10381/3678/4478/2260/7278/112714/3688/3672/1457/285643/6714/5605/6710/7846/113457/347733/10376/214/6709/3685/6196/10383/24137/1956/60/84790/3312/288/7280/5879/5595 39 Orf_virus R-HSA-9006936 Signaling by TGF-beta family members 35/1579 102/10654 6.643117751779522e-7 2.280394774423524e-6 9.502029279729076e-7 57154/5590/6497/10273/4738/4086/51592/3726/50848/54778/7316/9611/9612/6667/4609/4089/867/7050/4088/142/3065/9958/9040/4087/6233/7514/7048/1025/7311/25937/387/7040/57530/10589/7314 35 Orf_virus R-HSA-75893 TNF signaling 20/1579 43/10654 7.222818269391825e-7 2.47286488644178e-6 1.0304020522816591e-6 7124/7186/6885/8737/7375/841/27005/7316/7128/7132/329/9099/6233/7311/8772/8717/1540/3551/7185/7314 20 Orf_virus R-HSA-1236394 Signaling by ERBB4 24/1579 58/10654 8.279773942105963e-7 2.8272928867926135e-6 1.1780863600454677e-6 5295/6464/5290/2670/5241/348/6776/7316/1950/9611/4734/10413/6714/2099/83737/3925/6233/2885/7311/1956/3845/3265/7314/6387 24 Orf_virus R-HSA-5675482 Regulation of necroptotic cell death 12/1579 18/10654 8.391098231671385e-7 2.85780596843049e-6 1.1908006583937072e-6 7186/8737/356/841/7316/329/6233/7311/8772/8717/8795/7314 12 Orf_virus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 31/1579 86/10654 8.486398024606471e-7 2.867741254548836e-6 1.1949405284134879e-6 8454/1017/11065/991/9212/6500/5705/8881/7316/891/890/4085/983/6790/9861/5701/6502/5698/5708/5710/5702/8900/7324/9232/5704/6233/701/7311/5347/5696/7314 31 Orf_virus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 31/1579 86/10654 8.486398024606471e-7 2.867741254548836e-6 1.1949405284134879e-6 5295/26999/25/1072/5290/5335/51517/5747/5594/2268/919/3055/6850/6714/4067/917/3320/2534/695/2885/7525/3326/5580/7409/23191/60/5296/5581/10787/5879/5595 31 Orf_virus R-HSA-453276 Regulation of mitotic cell cycle 31/1579 86/10654 8.486398024606471e-7 2.867741254548836e-6 1.1949405284134879e-6 8454/1017/11065/991/9212/6500/5705/8881/7316/891/890/4085/983/6790/9861/5701/6502/5698/5708/5710/5702/8900/7324/9232/5704/6233/701/7311/5347/5696/7314 31 Orf_virus R-HSA-437239 Recycling pathway of L1 21/1579 47/10654 8.766849012449849e-7 2.9484872609291475e-6 1.228586058803763e-6 84617/51807/10382/5594/7277/10381/4478/7278/112714/285643/6714/7846/113457/347733/10376/6196/10383/24137/60/84790/7280 21 Orf_virus R-HSA-3247509 Chromatin modifying enzymes 71/1579 274/10654 8.793336335438195e-7 2.9484872609291475e-6 1.228586058803763e-6 84678/54014/6595/9070/10196/1019/8841/23326/55250/11091/4790/6597/6314/23186/2146/5978/9112/9219/8085/6871/5929/5931/8520/6598/6599/7403/9611/84289/5970/11143/9612/1108/2122/84444/8850/5928/10524/1387/55578/57459/3717/6604/8289/54815/2033/23512/6605/6602/55929/595/23210/6944/3066/3065/1107/23028/23135/10498/57504/80854/58508/1386/51317/60/8726/3276/6601/6187/53615/8648/4791 71 Orf_virus R-HSA-4839726 Chromatin organization 71/1579 274/10654 8.793336335438195e-7 2.9484872609291475e-6 1.228586058803763e-6 84678/54014/6595/9070/10196/1019/8841/23326/55250/11091/4790/6597/6314/23186/2146/5978/9112/9219/8085/6871/5929/5931/8520/6598/6599/7403/9611/84289/5970/11143/9612/1108/2122/84444/8850/5928/10524/1387/55578/57459/3717/6604/8289/54815/2033/23512/6605/6602/55929/595/23210/6944/3066/3065/1107/23028/23135/10498/57504/80854/58508/1386/51317/60/8726/3276/6601/6187/53615/8648/4791 71 Orf_virus R-HSA-6804758 Regulation of TP53 Activity through Acetylation 16/1579 30/10654 9.260688800678995e-7 3.0972123726692477e-6 1.2905573622918906e-6 9219/207/5931/84289/1108/5928/57459/54815/2033/3066/3065/7157/1107/5371/5300/53615 16 Orf_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 13/1579 21/10654 1.005650765823906e-6 3.3547478111202606e-6 1.3978681360305305e-6 4790/5567/5568/5970/5566/1387/4067/2534/2033/5971/3845/3265/5062 13 Orf_virus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 14/1579 24/10654 1.0569582023107527e-6 3.5168864992488214e-6 1.4654286557814987e-6 596/2309/5747/207/5594/1027/1950/595/2002/7514/1385/2353/1956/5595 14 Orf_virus R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 18/1579 37/10654 1.1387465799435304e-6 3.7764002950826487e-6 1.573563778443759e-6 27161/8841/57690/27327/192670/348/9611/9612/2033/192669/23028/6256/23112/7376/4343/26523/8648/10062 18 Orf_virus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 20/1579 44/10654 1.1407573527805388e-6 3.7764002950826487e-6 1.573563778443759e-6 6497/51592/3726/54778/7316/9611/9612/6667/4609/4089/7050/4088/142/3065/4087/6233/1025/7311/25937/7314 20 Orf_virus R-HSA-5617472 Activation of anterior HOX genes in hindbrain development during early embryogenesis 39/1579 122/10654 1.2298670495104569e-6 4.05077729471672e-6 1.6878921532255437e-6 9070/3725/5434/5440/8841/11091/2146/5430/8085/5436/5929/5931/5441/3213/5438/5431/7403/5435/5433/9611/9935/5928/22976/1387/5437/2033/23512/5439/6256/58508/23054/9063/8726/57472/7703/8202/5432/1959/7528 39 Orf_virus R-HSA-5619507 Activation of HOX genes during differentiation 39/1579 122/10654 1.2298670495104569e-6 4.05077729471672e-6 1.6878921532255437e-6 9070/3725/5434/5440/8841/11091/2146/5430/8085/5436/5929/5931/5441/3213/5438/5431/7403/5435/5433/9611/9935/5928/22976/1387/5437/2033/23512/5439/6256/58508/23054/9063/8726/57472/7703/8202/5432/1959/7528 39 Orf_virus R-HSA-2586552 Signaling by Leptin 9/1579 11/10654 1.4000177376142744e-6 4.587967447446275e-6 1.911730438476339e-6 3667/3953/9021/3952/6776/6774/3717/6777/5781 9 Orf_virus R-HSA-9020956 Interleukin-27 signaling 9/1579 11/10654 1.4000177376142744e-6 4.587967447446275e-6 1.911730438476339e-6 10148/6774/6772/3717/9466/3716/246778/7297/3572 9 Orf_virus R-HSA-5654743 Signaling by FGFR4 19/1579 41/10654 1.4684301696778737e-6 4.800069474248527e-6 2.000109858196522e-6 5295/10253/6464/5290/5335/5594/7316/6714/8569/867/2247/6233/2885/7311/3845/3265/5781/7314/5595 19 Orf_virus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 11/1579 16/10654 1.5580506636648156e-6 5.0675597835698125e-6 2.1115686625983685e-6 57154/5590/50848/7316/6233/7048/7311/387/7040/57530/7314 11 Orf_virus R-HSA-9614657 FOXO-mediated transcription of cell death genes 11/1579 16/10654 1.5580506636648156e-6 5.0675597835698125e-6 2.1115686625983685e-6 2308/2309/65018/10018/356/4303/1649/4800/1387/2033/604 11 Orf_virus R-HSA-68875 Mitotic Prophase 43/1579 142/10654 1.8289385692404074e-6 5.933788225889701e-6 2.4725117814905103e-6 4000/23165/5903/55706/7175/9631/5594/5925/348995/79023/9133/57122/23636/23310/7443/10762/10051/23511/891/53371/983/23279/4927/9688/79902/5519/9883/23225/8086/2010/64900/9972/55844/5347/54892/8021/129401/6418/55746/7112/10592/8480/5595 43 Orf_virus R-HSA-69205 G1/S-Specific Transcription 15/1579 28/10654 1.8951391360146858e-6 6.133273671530116e-6 2.5556340797265334e-6 8318/5422/1869/983/5111/4998/5928/990/81620/3065/8900/7298/1719/7083/6241 15 Orf_virus R-HSA-9012852 Signaling by NOTCH3 21/1579 49/10654 2.0233300874905085e-6 6.531891920161666e-6 2.7217317358171917e-6 23462/55534/3280/84441/10046/7316/1950/4854/6772/8850/1387/2033/9794/6233/7311/1956/9787/388585/3516/4851/7314 21 Orf_virus R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 14/1579 25/10654 2.074658286237141e-6 6.664519581221038e-6 2.776995496847635e-6 1017/994/2305/9133/891/993/890/983/5519/995/8900/7514/5347/7465 14 Orf_virus R-HSA-9006335 Signaling by Erythropoietin 14/1579 25/10654 2.074658286237141e-6 6.664519581221038e-6 2.776995496847635e-6 5295/6464/5290/5335/6776/4067/3717/2057/2885/2056/7409/3845/6777/3265 14 Orf_virus R-HSA-389357 CD28 dependent PI3K/Akt signaling 13/1579 22/10654 2.12442165920248e-6 6.790841716517018e-6 2.829631849189906e-6 5295/5290/207/941/64223/8503/2534/942/79109/2475/3932/5296/253260 13 Orf_virus R-HSA-9613829 Chaperone Mediated Autophagy 13/1579 22/10654 2.12442165920248e-6 6.790841716517018e-6 2.829631849189906e-6 2670/1915/1080/10013/7316/3320/6233/3326/7311/7431/3312/11315/7314 13 Orf_virus R-HSA-114604 GPVI-mediated activation cascade 17/1579 35/10654 2.330067068128667e-6 7.429944254008324e-6 3.0959353459397924e-6 5295/5777/5590/5290/388/6850/8503/4067/5880/2534/7409/3932/387/5296/5781/2207/5879 17 Orf_virus R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 10/1579 14/10654 2.812635654565917e-6 8.92497313802502e-6 3.718889248013985e-6 6118/4436/9156/2956/3978/5425/5111/6119/6117/5424 10 Orf_virus R-HSA-8941856 RUNX3 regulates NOTCH signaling 10/1579 14/10654 2.812635654565917e-6 8.92497313802502e-6 3.718889248013985e-6 55534/3280/84441/10046/8850/1387/2033/9794/3516/4851 10 Orf_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 16/1579 32/10654 2.849410610404127e-6 9.01966716334737e-6 3.758346688073058e-6 57154/10273/4738/7316/4089/867/4088/9958/9040/4087/6233/7514/7048/7311/7040/7314 16 Orf_virus R-HSA-72163 mRNA Splicing - Major Pathway 51/1579 183/10654 3.2777378534993886e-6 1.0350332396608506e-5 4.312812965130774e-6 23451/2963/5434/5440/220988/6632/10946/11051/5430/5436/6428/3184/3178/23450/5441/5438/5431/5093/5435/4686/5433/11338/1655/9343/3190/2962/988/5437/4670/10189/6631/3181/5439/1660/10285/3187/1665/6634/5094/51593/9775/3192/3312/10291/5432/22916/56259/5725/10992/6628/1994 51 Orf_virus R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK 15/1579 29/10654 3.3888967238971264e-6 1.0675434958329688e-5 4.4482778458188355e-6 389541/7249/58528/153129/64223/10325/8649/6009/10542/2475/55004/10670/64121/57521/28956 15 Orf_virus R-HSA-5610787 Hedgehog 'off' state 36/1579 113/10654 3.4180598158060306e-6 1.0734997258706718e-5 4.473096474965784e-6 8454/84617/5567/1452/10382/5568/6500/7277/10381/5705/7278/7316/9978/2778/9861/5566/2932/5701/7846/5576/113457/5698/347733/5708/10376/5710/5702/83737/5704/6233/7311/10383/84790/5696/7280/7314 36 Orf_virus R-HSA-69563 p53-Dependent G1 DNA Damage Response 25/1579 66/10654 3.4325586930222867e-6 1.0734997258706718e-5 4.473096474965784e-6 1017/9134/1029/1027/11200/472/5705/7316/890/1026/9861/4194/5701/5698/5708/5710/5702/7157/8900/5704/6233/7311/5696/7314/4193 25 Orf_virus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 25/1579 66/10654 3.4325586930222867e-6 1.0734997258706718e-5 4.473096474965784e-6 1017/9134/1029/1027/11200/472/5705/7316/890/1026/9861/4194/5701/5698/5708/5710/5702/7157/8900/5704/6233/7311/5696/7314/4193 25 Orf_virus R-HSA-912694 Regulation of IFNA signaling 14/1579 26/10654 3.8826900783288715e-6 1.2113620604090796e-5 5.0475461071295435e-6 5777/5770/3455/9021/11274/6772/8651/3454/3439/3716/3456/6773/7297/5781 14 Orf_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 29/1579 83/10654 3.928490023642794e-6 1.2227190241050899e-5 5.094868703540768e-6 8454/4773/4790/6885/5966/4772/5532/4775/6500/5705/5530/7316/5970/4792/9861/5701/23291/5698/5708/5710/5702/5704/6233/7311/3845/3265/3551/5696/7314 29 Orf_virus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 20/1579 47/10654 4.044838399120353e-6 1.2469987576435023e-5 5.196038352574162e-6 818/815/5604/8844/817/5594/409/6714/5605/3717/2335/408/1445/816/60/3845/3265/5245/7529/5595 20 Orf_virus R-HSA-6802949 Signaling by RAS mutants 20/1579 47/10654 4.044838399120353e-6 1.2469987576435023e-5 5.196038352574162e-6 818/815/5604/8844/817/5594/409/6714/5605/3717/2335/408/1445/816/60/3845/3265/5245/7529/5595 20 Orf_virus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 20/1579 47/10654 4.044838399120353e-6 1.2469987576435023e-5 5.196038352574162e-6 818/815/5604/8844/817/5594/409/6714/5605/3717/2335/408/1445/816/60/3845/3265/5245/7529/5595 20 Orf_virus R-HSA-9649948 Signaling downstream of RAS mutants 20/1579 47/10654 4.044838399120353e-6 1.2469987576435023e-5 5.196038352574162e-6 818/815/5604/8844/817/5594/409/6714/5605/3717/2335/408/1445/816/60/3845/3265/5245/7529/5595 20 Orf_virus R-HSA-3858494 Beta-catenin independent WNT signaling 43/1579 146/10654 4.093047403209937e-6 1.2588781729494392e-5 5.2455379187585355e-6 2788/57154/27161/815/54331/6885/1499/4772/5532/57690/27327/409/5705/192670/5530/7316/6934/9861/5701/5698/5708/5880/2783/5710/2782/5702/192669/2786/23112/5704/6233/1855/7474/1857/7311/387/4343/3845/26523/5696/7314/5879/2787 43 Orf_virus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 13/1579 23/10654 4.223190397221161e-6 1.2958421478265871e-5 5.39956071144215e-6 5601/6885/7316/5602/3654/7189/5609/6233/7311/5599/7334/6416/7314 13 Orf_virus R-HSA-5213460 RIPK1-mediated regulated necrosis 12/1579 20/10654 4.259153612745532e-6 1.3007415141272152e-5 5.419975563538297e-6 7186/8737/356/841/7316/329/6233/7311/8772/8717/8795/7314 12 Orf_virus R-HSA-5218859 Regulated Necrosis 12/1579 20/10654 4.259153612745532e-6 1.3007415141272152e-5 5.419975563538297e-6 7186/8737/356/841/7316/329/6233/7311/8772/8717/8795/7314 12 Orf_virus R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 21/1579 51/10654 4.400567250579922e-6 1.340781731382782e-5 5.586816551334056e-6 84617/5321/51807/10382/7277/10381/23299/7278/112714/1780/1639/636/7846/113457/347733/10376/10540/10383/84790/5049/7280 21 Orf_virus R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 23/1579 59/10654 4.755797306164835e-6 1.4456290409627219e-5 6.0236980144488184e-6 5000/23594/5705/7316/84515/9861/51053/4998/5701/5698/5708/990/5710/81620/5702/5704/6233/23595/7311/5001/5696/4999/7314 23 Orf_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 16/1579 33/10654 4.7729916345932354e-6 1.4474736868544986e-5 6.03138434993379e-6 351/4790/6885/7316/5970/4792/3146/6288/3654/7189/6233/7311/7334/3551/4791/7314 16 Orf_virus R-HSA-2029481 FCGR activation 9/1579 12/10654 4.858926334097775e-6 1.4599222080048973e-5 6.083255286399305e-6 2268/919/3055/6850/6714/4067/917/2534/7525 9 Orf_virus R-HSA-210990 PECAM1 interactions 9/1579 12/10654 4.858926334097775e-6 1.4599222080048973e-5 6.083255286399305e-6 5777/5335/6714/4067/2534/7525/3685/3932/5781 9 Orf_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 9/1579 12/10654 4.858926334097775e-6 1.4599222080048973e-5 6.083255286399305e-6 3665/29110/7098/7316/3661/6233/7311/7187/7314 9 Orf_virus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 9/1579 12/10654 4.858926334097775e-6 1.4599222080048973e-5 6.083255286399305e-6 8737/57506/841/7706/23586/843/64135/8772/3551 9 Orf_virus R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 29/1579 84/10654 5.160978933590172e-6 1.5471045144241506e-5 6.446529592042053e-6 7124/1052/1019/8841/4790/5468/1051/3952/688/5465/9611/5469/1050/5970/9612/1387/6604/2033/6256/10498/4023/9477/23054/7040/27332/8202/8648/1959/10891 29 Orf_virus R-HSA-442755 Activation of NMDA receptors and postsynaptic events 31/1579 93/10654 5.682726751458566e-6 1.6995925295741594e-5 7.081922025411158e-6 818/84617/815/3838/5567/51807/817/10382/5594/5568/7277/10381/7278/112714/6714/5566/7846/5576/113457/347733/10376/816/1385/6196/10383/84790/3845/3265/7280/5879/5595 31 Orf_virus R-HSA-1538133 G0 and Early G1 14/1579 27/10654 6.966279113279505e-6 2.0786993409120725e-5 8.66159764205443e-6 1017/9134/7153/4149/1869/993/890/983/5111/4609/5928/990/3065/8900 14 Orf_virus R-HSA-9609736 Assembly and cell surface presentation of NMDA receptors 18/1579 41/10654 7.196876305636241e-6 2.1425940671928486e-5 8.927836438402176e-6 818/84617/815/51807/817/10382/7277/10381/7278/112714/7846/113457/347733/10376/816/10383/84790/7280 18 Orf_virus R-HSA-5358508 Mismatch Repair 10/1579 15/10654 7.312814251395596e-6 2.1721395755857695e-5 9.050947703601855e-6 6118/4436/9156/2956/3978/5425/5111/6119/6117/5424 10 Orf_virus R-HSA-1368082 RORA activates gene expression 11/1579 18/10654 8.50795766273202e-6 2.521378797087553e-5 1.0506169994741613e-5 6095/1374/5465/5469/1387/6604/2033/6256/10498/23054/8648 11 Orf_virus R-HSA-445144 Signal transduction by L1 12/1579 21/10654 8.597157408641013e-6 2.536258908989106e-5 1.0568172969209025e-5 5604/5594/1460/3678/2260/3688/1457/5605/3685/1956/5879/5595 12 Orf_virus R-HSA-9008059 Interleukin-37 signaling 12/1579 21/10654 8.597157408641013e-6 2.536258908989106e-5 1.0568172969209025e-5 834/5777/5783/27178/29110/6774/59307/8809/4088/5771/5784/5781 12 Orf_virus R-HSA-177929 Signaling by EGFR 20/1579 49/10654 8.700624015438609e-6 2.5609755303361154e-5 1.067116305775395e-5 5295/10253/6464/5290/5335/58513/7316/1950/6714/867/1445/6233/2885/7311/1956/3845/3265/5781/10252/7314 20 Orf_virus R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 17/1579 38/10654 9.485973502230224e-6 2.7821643951044784e-5 1.1592820611503752e-5 1072/27250/6775/1265/4478/3313/6175/6647/6950/3458/3181/6648/2939/4507/302/5062/3586 17 Orf_virus R-HSA-2871837 FCERI mediated NF-kB activation 28/1579 82/10654 9.494857735790842e-6 2.7821643951044784e-5 1.1592820611503752e-5 8454/2205/4790/6885/6500/5705/2206/7316/5970/4792/9861/5701/4067/23291/5698/5708/5710/5702/7189/5704/6233/7311/7334/3551/5696/997/2207/7314 28 Orf_virus R-HSA-6807505 RNA polymerase II transcribes snRNA genes 26/1579 74/10654 1.09459111081571e-5 3.200141652070199e-5 1.3334462970315569e-5 2963/5434/5440/55197/2959/5430/5436/5451/5441/5438/5431/5435/4686/5433/2960/6667/2962/5437/5439/1025/6908/51593/2961/5432/22916/2957 26 Orf_virus R-HSA-194315 Signaling by Rho GTPases 101/1579 455/10654 1.1416501041203434e-5 3.330239429283782e-5 1.3876558971488715e-5 26999/5905/11130/84617/25/5590/5903/1072/10403/51517/55143/1499/7531/5747/1058/55789/991/79019/51807/2316/10928/3633/10382/9212/5594/613/29127/7074/1027/3619/388/1080/7277/348995/79023/10381/57122/58480/7278/6232/332/112714/1780/6242/5528/3688/4085/5585/6714/23279/79902/5519/1432/2017/699/7846/999/113457/396/347733/5880/22919/85360/995/10376/9322/58504/397/23221/23028/695/11004/90627/1855/2885/5580/701/7409/1857/9055/23191/7514/23380/57120/367/10383/5347/387/60/5296/5300/84790/5600/5062/55746/7280/7529/10787/5879/5595/10672 101 Orf_virus R-HSA-72172 mRNA Splicing 51/1579 191/10654 1.230814103964777e-5 3.5823023473337246e-5 1.492686361808219e-5 23451/2963/5434/5440/220988/6632/10946/11051/5430/5436/6428/3184/3178/23450/5441/5438/5431/5093/5435/4686/5433/11338/1655/9343/3190/2962/988/5437/4670/10189/6631/3181/5439/1660/10285/3187/1665/6634/5094/51593/9775/3192/3312/10291/5432/22916/56259/5725/10992/6628/1994 51 Orf_virus R-HSA-5654736 Signaling by FGFR1 20/1579 50/10654 1.2497751211554758e-5 3.6293692692483796e-5 1.5122983726387924e-005 5295/10253/6464/5290/5335/5594/2260/7316/6714/8569/867/2247/6233/2885/7311/3845/3265/5781/7314/5595 20 Orf_virus R-HSA-4086398 Ca2+ pathway 23/1579 62/10654 1.2568356646882658e-5 3.641744320176913e-5 1.5174548524544761e-5 2788/27161/815/54331/6885/1499/4772/5532/57690/27327/192670/5530/6934/2783/2782/192669/2786/23112/7474/4343/3845/26523/2787 23 Orf_virus R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 36/1579 119/10654 1.2676996653598682e-5 3.656934067922813e-5 1.5237841700556242e-5 6095/6822/8841/1374/5468/51/5465/406/335/9611/5469/4800/9612/6667/336/1387/6604/2033/2101/4199/6256/7376/2168/10498/183/2274/9477/23054/25942/196/405/8202/133522/8648/10891/10062 36 Orf_virus R-HSA-9612973 Autophagy 36/1579 119/10654 1.2676996653598682e-5 3.656934067922813e-5 1.5237841700556242e-5 2670/65018/1915/389541/7249/58528/1080/1460/10533/10013/153129/7316/1457/8678/6714/64223/10325/8649/3320/6009/55054/10542/6233/3326/2475/55004/7311/10670/7251/7431/3312/11315/64121/57521/7314/28956 36 Orf_virus R-HSA-171007 p38MAPK events 9/1579 13/10654 1.3704787672370209e-5 3.935966614073651e-5 1.6400524343605568e-5 9261/6714/7867/1432/5603/3845/5600/3265/6300 9 Orf_virus R-HSA-209543 p75NTR recruits signalling complexes 9/1579 13/10654 1.3704787672370209e-5 3.935966614073651e-5 1.6400524343605568e-5 4615/7316/4803/3654/7189/6233/7311/3551/7314 9 Orf_virus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 13/1579 25/10654 1.4346414300377128e-5 4.111164097971507e-5 1.7130543391361513e-5 5594/5528/4205/9261/5519/5598/1432/4208/2002/1385/6196/5600/5595 13 Orf_virus R-HSA-6802957 Oncogenic MAPK signaling 25/1579 71/10654 1.5408522487824665e-5 4.4058214849801955e-5 1.8358332171728636e-5 4000/818/815/8805/5604/10018/8844/817/5594/409/10533/6714/5605/3717/2335/408/1445/816/60/3845/3265/4763/5245/7529/5595 25 Orf_virus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 15/1579 32/10654 1.591352674783155e-5 4.5204144757486566e-5 1.8835822282540213e-5 3726/54778/7316/6667/4609/4089/7050/4088/3065/4087/6233/1025/7311/25937/7314 15 Orf_virus R-HSA-381042 PERK regulates gene expression 15/1579 32/10654 1.591352674783155e-5 4.5204144757486566e-5 1.8835822282540213e-5 1965/5073/1051/1649/3576/468/4800/1054/8894/9451/6347/467/8570/167227/1968 15 Orf_virus R-HSA-5673000 RAF activation 15/1579 32/10654 1.591352674783155e-5 4.5204144757486566e-5 1.8835822282540213e-5 818/815/5604/8844/817/5528/6714/5605/5519/3717/816/3845/3265/5245/7529 15 Orf_virus R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 10/1579 16/10654 1.6904086897613602e-5 4.79133269145867e-5 1.996469384765739e-5 55534/3280/84441/10046/8850/1387/2033/9794/3516/4851 10 Orf_virus R-HSA-9024446 NR1H2 and NR1H3-mediated signaling 19/1579 47/10654 1.71700457474612e-5 4.8561368516189174e-5 2.023472210513162e-5 27161/8841/8204/57690/27327/192670/348/9611/9612/2033/192669/23028/6256/23112/7376/4343/26523/8648/10062 19 Orf_virus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 27/1579 80/10654 1.738393531593444e-5 4.90596525944267e-5 2.04423488702049e-5 8454/1017/11065/991/6500/5705/8881/7316/891/890/4085/983/9861/5701/5698/5708/5710/5702/8900/7324/5704/6233/701/7311/5347/5696/7314 27 Orf_virus R-HSA-6804760 Regulation of TP53 Activity through Methylation 11/1579 19/10654 1.749808828398192e-5 4.92749196048928e-5 2.053204708646773e-5 11200/472/7316/4194/2033/7157/6233/7311/26013/7314/4193 11 Orf_virus R-HSA-5654732 Negative regulation of FGFR3 signaling 14/1579 29/10654 2.0109373299415105e-5 5.626299927427753e-5 2.344386474068767e-5 10253/5594/7316/6714/8569/2261/867/2247/6233/2885/7311/5781/7314/5595 14 Orf_virus R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 14/1579 29/10654 2.0109373299415105e-5 5.626299927427753e-5 2.344386474068767e-5 2308/2309/4303/5443/4089/4088/2908/3630/3066/3065/6648/4087/25942/10891 14 Orf_virus R-HSA-9619483 Activation of AMPK downstream of NMDARs 14/1579 29/10654 2.0109373299415105e-5 5.626299927427753e-5 2.344386474068767e-5 84617/51807/10382/7277/10381/7278/112714/7846/113457/347733/10376/10383/84790/7280 14 Orf_virus R-HSA-1989781 PPARA activates gene expression 35/1579 117/10654 2.1764280135571235e-5 6.052212997567667e-5 2.5218574325396243e-5 6095/6822/8841/1374/5468/51/5465/406/335/9611/5469/4800/9612/6667/336/1387/6604/2033/2101/4199/6256/7376/2168/10498/183/2274/9477/23054/196/405/8202/133522/8648/10891/10062 35 Orf_virus R-HSA-5674135 MAP2K and MAPK activation 17/1579 40/10654 2.177121969916732e-5 6.052212997567667e-5 2.5218574325396243e-5 5604/8844/84292/5594/409/6714/5605/8649/2335/408/1445/60/3845/3265/7529/28956/5595 17 Orf_virus R-HSA-5675221 Negative regulation of MAPK pathway 17/1579 40/10654 2.177121969916732e-5 6.052212997567667e-5 2.5218574325396243e-5 1844/5604/8844/5594/5528/7316/5605/5519/1847/6233/7311/1843/3845/3265/7529/7314/5595 17 Orf_virus R-HSA-75153 Apoptotic execution phase 20/1579 52/10654 2.48233096508103e-5 6.84484974857777e-5 2.8521361062482718e-5 4000/3837/1499/5747/63967/841/100506658/660/3146/329/999/836/3836/5580/6709/839/840/7431/5062/6304 20 Orf_virus R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 8/1579 11/10654 2.4832967573625732e-5 6.84484974857777e-5 2.8521361062482718e-5 7422/3091/1387/2033/2056/2034/405/768 8 Orf_virus R-HSA-174414 Processive synthesis on the C-strand of the telomere 8/1579 11/10654 2.4832967573625732e-5 6.84484974857777e-5 2.8521361062482718e-5 6118/2237/3978/5425/5111/6119/6117/5424 8 Orf_virus R-HSA-4755510 SUMOylation of immune response proteins 8/1579 11/10654 2.4832967573625732e-5 6.84484974857777e-5 2.8521361062482718e-5 51588/5970/4792/7341/10401/7329/6612/4791 8 Orf_virus R-HSA-2871809 FCERI mediated Ca+2 mobilization 15/1579 33/10654 2.5197306008863532e-5 6.930590933938996e-5 2.8878630454133127e-5 6464/4773/2205/5335/4772/5532/4775/2206/5530/6850/4067/695/2885/7409/2207 15 Orf_virus R-HSA-111885 Opioid Signalling 29/1579 91/10654 2.9631140502718612e-5 8.132935399585847e-5 3.388860172973592e-5 2788/818/815/3838/5321/54331/5567/2770/817/5532/5594/5568/5530/5528/5443/5566/5519/4988/5576/2783/2782/816/2786/2771/5580/1385/1020/2773/2787 29 Orf_virus R-HSA-8853659 RET signaling 17/1579 41/10654 3.209471293625173e-5 8.79057295369758e-5 3.662886905743965e-5 5295/6464/5290/5335/5567/5568/6714/5566/8503/5598/5979/2885/9846/9260/5296/5781/9046 17 Orf_virus R-HSA-2424491 DAP12 signaling 14/1579 30/10654 3.258481593964269e-5 8.906059986864527e-5 3.7110084495612535e-5 5295/6464/5290/5335/567/6850/2534/695/2885/3932/5296/3845/3265/5879 14 Orf_virus R-HSA-162594 Early Phase of HIV Life Cycle 9/1579 14/10654 3.3310661304418084e-5 9.028577157718319e-5 3.762059335915639e-5 2237/7852/3159/3978/3981/920/3836/2547/1234 9 Orf_virus R-HSA-198323 AKT phosphorylates targets in the cytosol 9/1579 14/10654 3.3310661304418084e-5 9.028577157718319e-5 3.762059335915639e-5 842/207/84335/1027/7249/1026/2932/2931/4193 9 Orf_virus R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 9/1579 14/10654 3.3310661304418084e-5 9.028577157718319e-5 3.762059335915639e-5 6118/4436/9156/3978/5425/5111/6119/6117/5424 9 Orf_virus R-HSA-9027284 Erythropoietin activates RAS 9/1579 14/10654 3.3310661304418084e-5 9.028577157718319e-5 3.762059335915639e-5 6464/4067/3717/2057/2885/2056/7409/3845/3265 9 Orf_virus R-HSA-6788467 IL-6-type cytokine receptor ligand interactions 10/1579 17/10654 3.559358312484214e-5 9.627287244369983e-5 4.01153196395529e-5 3589/3976/3717/3716/1270/5008/3977/7297/1489/3572 10 Orf_virus R-HSA-111465 Apoptotic cleavage of cellular proteins 16/1579 38/10654 4.359781028081167e-5 1.174342674437598e-4 4.8932924255460406e-5 4000/1499/5747/63967/841/100506658/660/329/999/836/5580/6709/839/840/7431/6304 16 Orf_virus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 16/1579 38/10654 4.359781028081167e-5 1.174342674437598e-4 4.8932924255460406e-5 7020/3815/7422/4869/2064/348/1026/2099/4609/3329/7341/1387/2033/7329/1956/7528 16 Orf_virus R-HSA-1234174 Cellular response to hypoxia 25/1579 75/10654 4.469193011839853e-5 1.2013264686784399e-4 5.0057294499728666e-5 112399/7422/3091/5705/7316/9978/8994/9861/5701/1387/5698/5708/2033/5710/5702/5704/6233/2056/7311/2034/55662/405/5696/768/7314 25 Orf_virus R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 17/1579 42/10654 4.653344064318823e-5 1.2482475520987193e-4 5.201241873302645e-5 9070/1487/1499/207/8085/5929/6657/7316/6934/3065/57680/6233/7514/7311/25776/6659/7314 17 Orf_virus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 12/1579 24/10654 5.125377924817432e-5 1.3636230429831244e-4 5.681992533163227e-5 6885/7316/9261/7867/1432/3654/7189/6233/7311/5600/7334/7314 12 Orf_virus R-HSA-452723 Transcriptional regulation of pluripotent stem cells 12/1579 24/10654 5.125377924817432e-5 1.3636230429831244e-4 5.681992533163227e-5 63978/79727/2516/6657/5460/6774/57167/4089/79923/2247/4087/2034 12 Orf_virus R-HSA-5260271 Diseases of Immune System 12/1579 24/10654 5.125377924817432e-5 1.3636230429831244e-4 5.681992533163227e-5 4790/7099/4615/7098/5970/4792/114609/695/7187/7097/3551/4791 12 Orf_virus R-HSA-5602358 Diseases associated with the TLR signaling cascade 12/1579 24/10654 5.125377924817432e-5 1.3636230429831244e-4 5.681992533163227e-5 4790/7099/4615/7098/5970/4792/114609/695/7187/7097/3551/4791 12 Orf_virus R-HSA-6802952 Signaling by BRAF and RAF fusions 23/1579 67/10654 5.299680715147635e-5 1.4071193082463416e-4 5.863234303546793e-5 4000/818/815/8805/5604/10018/8844/817/5594/409/10533/6714/5605/3717/2335/408/1445/816/60/3845/3265/7529/5595 23 Orf_virus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 25/1579 76/10654 5.735112218408147e-5 1.5196295307839104e-4 6.33204586232221e-5 11065/991/5705/8881/7316/891/890/4085/983/9861/5701/5698/5708/5710/5702/8900/7324/9232/5704/6233/701/7311/5347/5696/7314 25 Orf_virus R-HSA-380108 Chemokine receptors bind chemokines 21/1579 59/10654 6.066372974170753e-5 0.00016041364307715753 6.684172190196702e-5 729230/7852/6351/1230/2919/6367/6349/3576/2920/2921/6352/6348/3627/6364/4283/6363/2833/6347/6356/1234/6387 21 Orf_virus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 11/1579 21/10654 6.126904456969718e-5 1.613583542210041e-4 6.723536746940986e-5 4790/8737/29110/4615/7098/5970/4792/1660/3661/3551/4791 11 Orf_virus R-HSA-389513 CTLA4 inhibitory signaling 11/1579 21/10654 6.126904456969718e-5 1.613583542210041e-4 6.723536746940986e-5 207/941/5528/6714/5519/4067/2534/942/7525/3932/5781 11 Orf_virus R-HSA-8941858 Regulation of RUNX3 expression and activity 20/1579 55/10654 6.375888263815135e-5 1.6757637638835333e-4 6.982631485092599e-5 57154/1029/5705/7316/865/6714/9861/5701/5698/5708/2033/5710/5702/5704/6233/7311/7040/5696/7314/4193 20 Orf_virus R-HSA-389359 CD28 dependent Vav1 pathway 8/1579 12/10654 6.478105005268171e-5 1.6991964943253814e-4 7.080271811785034e-5 941/2534/942/2885/7409/3932/5062/5879 8 Orf_virus R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 10/1579 18/10654 6.945061495247999e-5 1.8107264539714724e-4 7.54499877661158e-5 891/983/6790/5111/1647/2033/995/7157/10498/3276 10 Orf_virus R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 10/1579 18/10654 6.945061495247999e-5 1.8107264539714724e-4 7.54499877661158e-5 5594/4314/5598/2885/1385/6196/1956/3845/3265/5595 10 Orf_virus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 10/1579 18/10654 6.945061495247999e-5 1.8107264539714724e-4 7.54499877661158e-5 3665/29110/7099/7316/3661/6233/7311/7187/5781/7314 10 Orf_virus R-HSA-392518 Signal amplification 14/1579 32/10654 7.892458317638169e-5 2.0536176542494515e-4 8.55708638649191e-5 2788/5321/54331/2770/2767/6714/1432/2783/2782/2786/2771/2773/2787/10672 14 Orf_virus R-HSA-5610783 Degradation of GLI2 by the proteasome 21/1579 60/10654 8.044979445596438e-5 2.0849637965579613e-4 8.687700596523728e-5 8454/5567/1452/5568/6500/5705/7316/9978/9861/5566/2932/5701/5698/5708/5710/5702/5704/6233/7311/5696/7314 21 Orf_virus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 21/1579 60/10654 8.044979445596438e-5 2.0849637965579613e-4 8.687700596523728e-5 8454/5567/1452/5568/6500/5705/7316/9978/9861/5566/2932/5701/5698/5708/5710/5702/5704/6233/7311/5696/7314 21 Orf_virus R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 20/1579 56/10654 8.552009564491187e-5 2.2119611219489135e-4 9.216877525819736e-5 8841/5465/4209/9611/5469/54205/4208/1387/6604/2101/6648/6256/10498/1385/23054/1386/23373/133522/8648/10891 20 Orf_virus R-HSA-212165 Epigenetic regulation of gene expression 40/1579 149/10654 9.095853576651819e-5 2.3433080204403995e-4 9.764178409537647e-5 23451/5434/5440/2146/29128/9112/9219/1786/404672/5931/5441/5435/6996/1108/2966/8850/5928/2932/29947/5437/57459/2965/54815/2033/23512/2068/3066/3065/2071/1107/2968/57504/2967/6908/23411/60/25942/8726/53615/9188 40 Orf_virus R-HSA-5358351 Signaling by Hedgehog 40/1579 149/10654 9.095853576651819e-5 2.3433080204403995e-4 9.764178409537647e-5 8454/57154/84617/5567/1452/10382/5568/6500/409/7277/10381/5705/7278/7316/9978/2778/7415/9861/5566/2932/5701/7846/5576/113457/5698/347733/5708/408/10376/5710/5702/83737/5704/6233/7311/10383/84790/5696/7280/7314 40 Orf_virus R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 13/1579 29/10654 1.047527820174341e-4 2.6880348995006264e-4 1.1200598513231303e-4 5434/5440/5430/5436/5441/5438/5431/5435/5433/5437/3320/5439/5432 13 Orf_virus R-HSA-933541 TRAF6 mediated IRF7 activation 13/1579 29/10654 1.047527820174341e-4 2.6880348995006264e-4 1.1200598513231303e-4 3665/7186/29110/57506/7706/23586/1387/2033/64135/3661/7189/3439/3456 13 Orf_virus R-HSA-198753 ERK/MAPK targets 11/1579 22/10654 1.0617364883142702e-4 2.7191322269623334e-4 1.1330175952794223e-4 5594/5528/4205/5519/5598/1432/4208/2002/6196/5600/5595 11 Orf_virus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 27/1579 88/10654 1.1438973251374751e-4 2.9237925736814443e-4 1.218296189527039e-4 8454/22981/7531/203068/54801/10382/6500/7277/9133/7316/891/983/1639/6790/5566/23291/7846/3320/22919/10540/10733/1069/6233/7311/10383/5347/7314 27 Orf_virus R-HSA-1980145 Signaling by NOTCH2 14/1579 33/10654 1.1851310319455324e-4 3.017329691900465e-4 1.257271565458748e-4 2208/55534/3280/84441/10046/7316/2033/9794/6233/1385/7311/388585/3516/7314 14 Orf_virus R-HSA-5654726 Negative regulation of FGFR1 signaling 14/1579 33/10654 1.1851310319455324e-4 3.017329691900465e-4 1.257271565458748e-4 10253/5594/2260/7316/6714/8569/867/2247/6233/2885/7311/5781/7314/5595 14 Orf_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 19/1579 53/10654 1.2060745811194586e-4 3.064654355539874e-4 1.2769909730191636e-4 596/10018/7531/1029/842/207/5594/841/1869/6774/54205/598/836/7157/7161/840/5599/7529/5595 19 Orf_virus R-HSA-174437 Removal of the Flap Intermediate from the C-strand 7/1579 10/10654 1.231830582108203e-4 3.111867159850043e-4 1.2966637706402135e-4 6118/2237/5425/5111/6119/6117/5424 7 Orf_virus R-HSA-8877330 RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) 7/1579 10/10654 1.231830582108203e-4 3.111867159850043e-4 1.2966637706402135e-4 4773/865/3558/50943/3458/861/3559 7 Orf_virus R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 7/1579 10/10654 1.231830582108203e-4 3.111867159850043e-4 1.2966637706402135e-4 2308/2309/4303/8850/1387/2033/23411 7 Orf_virus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 24/1579 75/10654 1.3081514096268014e-4 3.2982654727218387e-4 1.3743328762909072e-4 11065/991/5705/8881/7316/891/890/4085/983/9861/5701/5698/5708/5710/5702/8900/7324/9232/5704/6233/701/7311/5696/7314 24 Orf_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 12/1579 26/10654 1.3718952549504043e-4 3.452293475223358e-4 1.438513806982507e-4 57154/10273/7316/4088/9958/4087/6233/7514/7048/7311/7040/7314 12 Orf_virus R-HSA-156711 Polo-like kinase mediated events 9/1579 16/10654 1.435403040092432e-4 3.605133890270761e-4 1.5021998895500965e-4 2305/9133/891/993/5928/2033/995/5347/7465 9 Orf_virus R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 8/1579 13/10654 1.4650306986117986e-4 3.67245652966079e-4 1.530252124095074e-4 7531/11200/891/983/995/1111/7465/7529 8 Orf_virus R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 28/1579 94/10654 1.5212451973752565e-4 3.806038464971555e-4 1.585913515482302e-4 84617/22981/7531/203068/54801/51807/10382/7277/10381/7278/112714/983/1639/5566/7846/113457/347733/3320/22919/10376/10426/10540/10733/1069/10383/5347/84790/7280 28 Orf_virus R-HSA-525793 Myogenesis 13/1579 30/10654 1.5994005019456957e-4 3.993896454954606e-4 1.6641908445338586e-4 6925/25/9043/1499/4209/4205/1432/4208/1000/4654/5600/6300/4656 13 Orf_virus R-HSA-74751 Insulin receptor signalling cascade 19/1579 54/10654 1.6053388822919427e-4 4.001045758355972e-4 1.6671698414606786e-4 5295/54106/6464/5290/3667/5594/2322/2260/2263/2261/2247/3630/2885/9846/5296/3845/3265/5781/5595 19 Orf_virus R-HSA-1169091 Activation of NF-kappaB in B cells 22/1579 67/10654 1.617798084270727e-4 4.0243887335300496e-4 1.676896474588758e-4 8454/4790/6885/5966/6500/5705/7316/5970/4792/9861/5701/23291/5698/5708/5710/5702/5704/6233/7311/3551/5696/7314 22 Orf_virus R-HSA-5654727 Negative regulation of FGFR2 signaling 14/1579 34/10654 1.7420913007709952e-4 4.32530683645623e-4 1.8022840897891976e-4 10253/5594/7316/2263/6714/8569/867/2247/6233/2885/7311/5781/7314/5595 14 Orf_virus R-HSA-389948 PD-1 signaling 11/1579 23/10654 1.7635750673385345e-4 4.370306976395111e-4 1.8210349066252537e-4 5777/919/920/29126/915/917/1445/916/3932/3127/5781 11 Orf_virus R-HSA-186712 Regulation of beta-cell development 16/1579 42/10654 1.8158340376653377e-4 4.491254910651339e-4 1.8714319179460653e-4 2308/3172/3171/207/55534/3280/6927/84441/10046/8850/1387/2033/3630/9794/3516/4851 16 Orf_virus R-HSA-1368108 BMAL1:CLOCK,NPAS2 activates circadian gene expression 12/1579 27/10654 2.1383759665491152e-4 5.268990781212876e-4 2.1955016402966395e-4 10135/28999/5465/406/5469/8553/1387/6604/6256/10498/23054/8648 12 Orf_virus R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 12/1579 27/10654 2.1383759665491152e-4 5.268990781212876e-4 2.1955016402966395e-4 7186/842/8737/356/841/7099/9500/836/1630/8772/8717/8795 12 Orf_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 10/1579 20/10654 2.2067228073057409e-4 5.416879947744847e-4 2.257124619190579e-4 8737/7098/7316/329/7189/6233/7311/7334/3551/7314 10 Orf_virus R-HSA-8876384 Listeria monocytogenes entry into host cells 10/1579 20/10654 2.2067228073057409e-4 5.416879947744847e-4 2.257124619190579e-4 1499/7316/4233/6714/867/999/6233/2885/7311/7314 10 Orf_virus R-HSA-141424 Amplification of signal from the kinetochores 28/1579 96/10654 2.2572442296102548e-4 5.52006530587019e-4 2.300120257715238e-4 5905/11130/5903/10403/55143/1058/991/79019/9212/3619/348995/79023/57122/6232/332/1780/5528/4085/23279/79902/5519/699/22919/11004/701/7514/5347/55746 28 Orf_virus R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 28/1579 96/10654 2.2572442296102548e-4 5.52006530587019e-4 2.300120257715238e-4 5905/11130/5903/10403/55143/1058/991/79019/9212/3619/348995/79023/57122/6232/332/1780/5528/4085/23279/79902/5519/699/22919/11004/701/7514/5347/55746 28 Orf_virus R-HSA-5654733 Negative regulation of FGFR4 signaling 13/1579 31/10654 2.3836096434311525e-4 5.818154120270037e-4 2.424328955005517e-4 10253/5594/7316/6714/8569/867/2247/6233/2885/7311/5781/7314/5595 13 Orf_virus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 20/1579 60/10654 2.524705264232696e-4 6.139516913582687e-4 2.5582355358186684e-4 8454/6500/5705/7316/5970/9861/5701/23291/5698/5708/5710/5702/9040/5704/6233/7311/5971/5696/4791/7314 20 Orf_virus R-HSA-5610780 Degradation of GLI1 by the proteasome 20/1579 60/10654 2.524705264232696e-4 6.139516913582687e-4 2.5582355358186684e-4 8454/5567/5568/6500/5705/7316/9978/9861/5566/5701/5698/5708/5710/5702/83737/5704/6233/7311/5696/7314 20 Orf_virus R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 15/1579 39/10654 2.5415645746375824e-4 6.168984163439356e-4 2.570514053296062e-4 10694/9134/8841/10575/7203/10576/908/6774/6950/55294/7157/10574/6468/22948/10693 15 Orf_virus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 9/1579 17/10654 2.649803650041941e-4 6.407796558930418e-4 2.6700232435366845e-4 4790/8737/4615/7098/5970/4792/1660/3551/4791 9 Orf_virus R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 9/1579 17/10654 2.649803650041941e-4 6.407796558930418e-4 2.6700232435366845e-4 2308/2309/4303/1027/1026/4089/1647/4088/4087 9 Orf_virus R-HSA-193704 p75 NTR receptor-mediated signalling 28/1579 97/10654 2.732260033813995e-4 6.594935628927657e-4 2.7480010104759446e-4 8841/4790/10018/7531/835/7074/4615/9500/7316/5970/4792/836/396/4803/11108/3066/3065/3654/7189/6233/7409/7311/387/5599/3551/7314/5879/10672 28 Orf_virus R-HSA-3371378 Regulation by c-FLIP 7/1579 11/10654 2.9529571682591096e-4 7.049169313587342e-4 2.937272702372654e-4 7186/8737/356/841/8772/8717/8795 7 Orf_virus R-HSA-376172 DSCAM interactions 7/1579 11/10654 2.9529571682591096e-4 7.049169313587342e-4 2.937272702372654e-4 1432/5603/1630/5599/5600/6300/5879 7 Orf_virus R-HSA-5218900 CASP8 activity is inhibited 7/1579 11/10654 2.9529571682591096e-4 7.049169313587342e-4 2.937272702372654e-4 7186/8737/356/841/8772/8717/8795 7 Orf_virus R-HSA-69416 Dimerization of procaspase-8 7/1579 11/10654 2.9529571682591096e-4 7.049169313587342e-4 2.937272702372654e-4 7186/8737/356/841/8772/8717/8795 7 Orf_virus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 7/1579 11/10654 2.9529571682591096e-4 7.049169313587342e-4 2.937272702372654e-4 6885/7098/7316/7189/6233/7311/7314 7 Orf_virus R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 7/1579 11/10654 2.9529571682591096e-4 7.049169313587342e-4 2.937272702372654e-4 627/4915/4909/2885/3845/3265/5781 7 Orf_virus R-HSA-3371568 Attenuation phase 8/1579 14/10654 2.9742628127019593e-4 7.074069322349633e-4 2.9476481257413817e-4 1387/3320/2033/3326/3312/3297/2288/10728 8 Orf_virus R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 8/1579 14/10654 2.9742628127019593e-4 7.074069322349633e-4 2.9476481257413817e-4 1017/9134/1027/1869/890/1026/7157/8900 8 Orf_virus R-HSA-69618 Mitotic Spindle Checkpoint 31/1579 112/10654 3.020388701559249e-4 7.170667337095954e-4 2.987898926821001e-4 5905/11130/5903/10403/11065/55143/1058/991/79019/9212/3619/348995/79023/57122/6232/332/1780/8881/5528/4085/23279/79902/5519/699/22919/7324/11004/701/7514/5347/55746 31 Orf_virus R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 13/1579 32/10654 3.4744901461508903e-4 8.218748509349651e-4 3.424617081852074e-4 2788/54331/5594/409/2767/6714/408/2783/2782/2786/5595/2787/10672 13 Orf_virus R-HSA-73863 RNA Polymerase I Transcription Termination 13/1579 32/10654 3.4744901461508903e-4 8.218748509349651e-4 3.424617081852074e-4 5434/5440/404672/5441/5435/2966/5437/2965/2068/2071/2968/2967/6908 13 Orf_virus R-HSA-190861 Gap junction assembly 14/1579 36/10654 3.5538698300324777e-4 8.376059146507707e-4 3.4901658323164116e-4 84617/51807/10382/7277/10381/7278/112714/7846/113457/347733/10376/10383/84790/7280 14 Orf_virus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 14/1579 36/10654 3.5538698300324777e-4 8.376059146507707e-4 3.4901658323164116e-4 5604/8844/5594/409/6714/5605/2335/408/1445/60/3845/3265/7529/5595 14 Orf_virus R-HSA-69541 Stabilization of p53 19/1579 57/10654 3.57731859009679e-4 8.416078636014328e-4 3.5068412941845374e-4 1029/11200/472/5705/7316/9861/4194/5701/5698/5708/5710/5702/7157/5704/6233/7311/5696/7314/4193 19 Orf_virus R-HSA-6807004 Negative regulation of MET activity 10/1579 21/10654 3.6558431360409675e-4 8.585292274348915e-4 3.57734982911096e-4 5770/3082/7316/4233/867/5771/6233/2885/7311/7314 10 Orf_virus R-HSA-2428924 IGF1R signaling cascade 18/1579 53/10654 3.9175421382812206e-4 9.183283462889853e-4 3.826522904153302e-4 5295/54106/6464/5290/3667/2322/2260/2263/2261/2247/2885/9846/3479/5296/3845/3265/5781/3480 18 Orf_virus R-HSA-1632852 Macroautophagy 27/1579 95/10654 4.579851909177152e-4 0.0010716523981725674 4.465398964835731e-4 65018/389541/7249/58528/1460/10533/153129/7316/1457/8678/6714/64223/10325/8649/6009/55054/10542/6233/2475/55004/7311/10670/3312/64121/57521/7314/28956 27 Orf_virus R-HSA-210993 Tie2 Signaling 9/1579 18/10654 4.6051011505590856e-4 0.0010756259599420772 4.4819561419974095e-4 5295/6464/5290/2885/5296/3845/3265/5781/9046 9 Orf_virus R-HSA-5619115 Disorders of transmembrane transporters 43/1579 176/10654 4.87693243522072e-4 0.0011370768993229671 4.738012081001077e-4 23165/5903/55706/7175/9631/1080/348995/79023/57122/5705/23636/10762/23511/26503/7316/335/53371/23279/4927/9688/7415/9861/79902/9883/5701/23225/5698/5708/5710/5702/8086/6520/5704/6233/7311/9972/8021/129401/213/55746/5696/8480/7314 43 Orf_virus R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 18/1579 54/10654 5.073643766275851e-4 0.001178131036072287 4.909077904261725e-4 5295/54106/6464/5290/3667/2322/2260/2263/2261/2247/2885/9846/3479/5296/3845/3265/5781/3480 18 Orf_virus R-HSA-9604323 Negative regulation of NOTCH4 signaling 18/1579 54/10654 5.073643766275851e-4 0.001178131036072287 4.909077904261725e-4 8454/207/6500/5705/7316/9978/9861/5701/5698/5708/55294/5710/5702/5704/6233/7311/5696/7314 18 Orf_virus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 22/1579 72/10654 5.089236297253077e-4 0.001178131036072287 4.909077904261725e-4 11065/991/9212/5705/8881/7316/6790/9861/5701/6502/5698/5708/5710/5702/7324/9232/5704/6233/7311/5347/5696/7314 22 Orf_virus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 22/1579 72/10654 5.089236297253077e-4 0.001178131036072287 4.909077904261725e-4 11065/991/5705/8881/7316/890/4085/983/9861/5701/5698/5708/5710/5702/8900/7324/5704/6233/701/7311/5696/7314 22 Orf_virus R-HSA-937039 IRAK1 recruits IKK complex 8/1579 15/10654 5.547049662830461e-4 0.0012795211176855935 5.331553668094022e-4 7316/3654/7189/6233/7311/7334/3551/7314 8 Orf_virus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 8/1579 15/10654 5.547049662830461e-4 0.0012795211176855935 5.331553668094022e-4 7316/3654/7189/6233/7311/7334/3551/7314 8 Orf_virus R-HSA-1852241 Organelle biogenesis and maintenance 65/1579 296/10654 5.556721225921294e-4 0.0012795211176855935 5.331553668094022e-4 6102/10694/55763/84617/8841/22981/7531/203068/54801/51807/10575/10382/7277/10013/10381/7278/3313/112714/5465/4209/7203/10576/9611/5469/10989/983/1639/54205/5566/1432/4208/1387/6950/55212/7846/113457/6604/347733/3320/8729/22919/2101/10376/10540/10733/6648/1069/6256/117177/10498/1385/23054/10383/1386/5347/84790/22948/56623/5600/6300/23373/133522/8648/7280/10891 65 Orf_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 24/1579 82/10654 5.836756998843369e-4 0.00134130600380551 5.589001108134129e-4 8454/1487/1499/1452/6500/5705/5528/7316/9978/6934/9861/5519/2932/5701/5698/5708/5710/5702/3065/5704/6233/7311/5696/7314 24 Orf_virus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 19/1579 59/10654 5.845661061934851e-4 0.00134130600380551 5.589001108134129e-4 8454/6500/5705/7316/9861/5701/23291/5698/5708/5710/5702/9040/5704/6233/7311/5971/5696/4791/7314 19 Orf_virus R-HSA-170968 Frs2-mediated activation 7/1579 12/10654 6.180162503084316e-4 0.0014105949853531047 5.877716877356275e-4 5604/5594/5605/4914/4803/7529/5595 7 Orf_virus R-HSA-5689877 Josephin domain DUBs 7/1579 12/10654 6.180162503084316e-4 0.0014105949853531047 5.877716877356275e-4 7316/7415/6233/7311/5887/5886/7314 7 Orf_virus R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 7/1579 12/10654 6.180162503084316e-4 0.0014105949853531047 5.877716877356275e-4 834/835/472/843/7157/7161/839 7 Orf_virus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 22/1579 73/10654 6.282071108687506e-4 0.0014313440477062077 5.964174801316372e-4 11065/991/5705/8881/7316/890/4085/983/9861/5701/5698/5708/5710/5702/8900/7324/5704/6233/701/7311/5696/7314 22 Orf_virus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 28/1579 102/10654 6.691907940730798e-4 0.001522058082323561 6.34216523643055e-4 8454/7124/7186/356/8600/6500/5705/7316/7133/9861/7132/5701/329/23291/5698/5708/5710/5702/9040/5704/6233/7311/5971/7187/958/5696/4791/7314 28 Orf_virus R-HSA-8948751 Regulation of PTEN stability and activity 21/1579 69/10654 7.170475557927738e-4 0.0016280608552991251 6.783861325126821e-4 10273/207/1460/5705/7316/1457/4734/9861/5701/5698/5708/5728/5710/5702/8975/5987/5704/6233/7311/5696/7314 21 Orf_virus R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 9/1579 19/10654 7.605111384804963e-4 0.001723736918402658 7.182527715339366e-4 7153/4149/1869/993/5111/4609/5928/990/3065 9 Orf_virus R-HSA-8856688 Golgi-to-ER retrograde transport 34/1579 133/10654 7.813294683320934e-4 0.0017678428492174842 7.36630986162065e-4 55582/84617/5321/51807/23095/10382/29127/3832/7277/10381/23299/7278/112714/1780/23303/1639/285643/10112/636/7846/113457/347733/8729/10376/10540/4905/11004/10749/10383/24137/84790/9493/5049/7280 34 Orf_virus R-HSA-6806834 Signaling by MET 23/1579 79/10654 8.166644414770521e-4 0.0018445840943778554 7.686077985392578e-4 5295/6464/5290/5770/5747/3082/3688/7316/6774/4233/6714/867/2335/5771/3913/6233/2885/7311/3845/3265/5781/7314/5879 23 Orf_virus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 18/1579 56/10654 8.288230640857767e-4 0.0018688020907722627 7.786990385919457e-4 3184/3315/26986/5705/7316/9861/5701/5698/5708/1981/5710/5702/5704/6233/7311/3312/5696/7314 18 Orf_virus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 10/1579 23/10654 8.93607837463992e-4 0.0020113906514544182 8.3811334236743e-4 11065/991/8881/7316/891/983/7324/6233/7311/7314 10 Orf_virus R-HSA-8955332 Carboxyterminal post-translational modifications of tubulin 14/1579 39/10654 9.145814460914476e-4 0.0020550439747236155 8.563029628890019e-4 84617/51807/10382/7277/10381/7278/112714/7846/113457/347733/10376/10383/84790/7280 14 Orf_virus R-HSA-5619102 SLC transporter disorders 27/1579 99/10654 9.229362231250802e-4 0.002066300520642891 8.609933800971632e-4 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/26503/53371/23279/4927/9688/79902/9883/23225/8086/6520/9972/8021/129401/213/55746/8480 27 Orf_virus R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic 27/1579 99/10654 9.229362231250802e-4 0.002066300520642891 8.609933800971632e-4 55582/84617/51807/23095/10382/29127/3832/7277/10381/7278/112714/23303/285643/10112/7846/113457/347733/8729/10376/4905/11004/10749/10383/24137/84790/9493/7280 27 Orf_virus R-HSA-2428928 IRS-related events triggered by IGF1R 17/1579 52/10654 9.247066464874662e-4 0.002066300520642891 8.609933800971632e-4 5295/54106/5290/3667/2322/2260/2263/2261/2247/2885/9846/3479/5296/3845/3265/5781/3480 17 Orf_virus R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 19/1579 61/10654 9.259440457608035e-4 0.002066300520642891 8.609933800971632e-4 26999/25/1072/51517/5747/5594/919/6850/917/3320/695/2885/3326/7409/23191/60/10787/5879/5595 19 Orf_virus R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress 11/1579 27/10654 9.61192952487471e-4 0.002141287724633904 8.922393124207778e-4 5073/1051/1649/3576/468/4800/1054/6347/467/8570/167227 11 Orf_virus R-HSA-195721 Signaling by WNT 70/1579 331/10654 0.0010430608556023608 0.0023196960224592675 9.665791104547292e-4 2788/8454/57154/9070/27161/815/54331/6885/1487/6597/1499/4772/207/8085/1452/5532/57690/5929/6500/27327/409/1460/5705/6657/192670/5530/5528/7316/9978/51699/1457/9559/6934/4609/9861/5519/2932/5701/10524/1387/5698/5708/5880/2033/2783/5710/2782/5702/192669/3065/2786/23112/57680/5704/6233/1855/7474/1857/7514/7311/387/4343/25776/3845/6659/26523/5696/7314/5879/2787 70 Orf_virus R-HSA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 7/1579 13/10654 0.0011681149608302232 0.002588956667870733 0.0010787755847351652 5925/5557/5422/1869/5519/23649/5558 7 Orf_virus R-HSA-68884 Mitotic Telophase/Cytokinesis 7/1579 13/10654 0.0011681149608302232 0.002588956667870733 0.0010787755847351652 23244/5885/10112/8243/9126/5347/9493 7 Orf_virus R-HSA-622312 Inflammasomes 9/1579 20/10654 0.001202197476639528 0.002659964144741541 0.0011083632303425653 834/596/351/4790/29108/5970/598/3326/4791 9 Orf_virus R-HSA-6783310 Fanconi Anemia Pathway 14/1579 40/10654 0.0012177657863180113 0.0026898358030555732 0.0011208102581606216 6118/2176/2178/545/7316/6119/84464/2177/84126/55215/6233/7311/6117/7314 14 Orf_virus R-HSA-74749 Signal attenuation 6/1579 10/10654 0.001287815695400282 0.0028301490197901466 0.0011792764636044545 6464/3667/5594/3630/2885/5595 6 Orf_virus R-HSA-8853334 Signaling by FGFR3 fusions in cancer 6/1579 10/10654 0.001287815695400282 0.0028301490197901466 0.0011792764636044545 5295/5290/2261/2885/3845/3265 6 Orf_virus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 6/1579 10/10654 0.001287815695400282 0.0028301490197901466 0.0011792764636044545 6885/7316/7189/6233/7311/7314 6 Orf_virus R-HSA-157858 Gap junction trafficking and regulation 16/1579 49/10654 0.001314628336035962 0.0028842014589928948 0.0012017992243871845 84617/51807/10382/7277/10381/7278/112714/6714/7846/113457/347733/10376/10383/60/84790/7280 16 Orf_virus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 21/1579 72/10654 0.0013191019336148474 0.0028842884296351535 0.0012018354636207807 55763/84617/7531/51807/207/10382/7277/10381/7278/112714/7846/113457/347733/10376/9882/10383/60/84790/7280/7529/5879 21 Orf_virus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 21/1579 72/10654 0.0013191019336148474 0.0028842884296351535 0.0012018354636207807 1017/9134/11065/5705/8881/7316/890/9861/5701/5698/5708/990/5710/5702/8900/7324/5704/6233/7311/5696/7314 21 Orf_virus R-HSA-449836 Other interleukin signaling 10/1579 24/10654 0.0013303173592853837 0.002903931014144772 0.0012100202049310713 1435/920/1441/1440/836/163702/3716/282618/3588/7297 10 Orf_virus R-HSA-202733 Cell surface interactions at the vascular wall 34/1579 137/10654 0.0013620517611236513 0.0029682233521304362 0.0012368097628117436 5295/5777/6464/5290/5335/960/3684/4312/3678/6383/50848/3688/6714/4067/140885/2335/2534/6520/2885/7525/3685/3932/5296/7040/3687/3845/3265/5781/8795/3689/2207/3676/9046/3655 34 Orf_virus R-HSA-202040 G-protein activation 11/1579 28/10654 0.0013734238064906387 0.002988000622482142 0.0012450506254931858 2788/54331/2770/5443/4988/2783/2782/2786/2771/2773/2787 11 Orf_virus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 17/1579 54/10654 0.0014837635551477706 0.0032226650838852247 0.0013428314399457023 8454/6500/5705/7316/9978/6790/9861/5701/5698/5708/5710/5702/5704/6233/7311/5696/7314 17 Orf_virus R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 8/1579 17/10654 0.0015888823072703192 0.0034337805344828655 0.0014307997696174405 7186/8737/356/841/7099/8772/8717/8795 8 Orf_virus R-HSA-180292 GAB1 signalosome 8/1579 17/10654 0.0015888823072703192 0.0034337805344828655 0.0014307997696174405 5295/5290/1950/6714/1445/2885/1956/5781 8 Orf_virus R-HSA-9022699 MECP2 regulates neuronal receptors and channels 8/1579 17/10654 0.0015888823072703192 0.0034337805344828655 0.0014307997696174405 5770/4233/2289/4988/3066/3065/1385/25942 8 Orf_virus R-HSA-1236974 ER-Phagosome pathway 23/1579 83/10654 0.0017025869636881697 0.0036734090211580574 0.0015306490116075888 5705/7099/4615/7316/567/3106/9861/5701/5698/5708/114609/2923/5710/5702/695/5704/6233/7311/7097/3551/3105/5696/7314 23 Orf_virus R-HSA-5218920 VEGFR2 mediated vascular permeability 11/1579 29/10654 0.001920047591523686 0.00412108544184822 0.001717188399653573 1499/207/64223/3320/4846/79109/2475/7409/5062/5879/253260 11 Orf_virus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 10/1579 25/10654 0.0019259184847376773 0.00412108544184822 0.001717188399653573 11065/991/8881/7316/4085/7324/6233/701/7311/7314 10 Orf_virus R-HSA-418592 ADP signalling through P2Y purinoceptor 1 10/1579 25/10654 0.0019259184847376773 0.00412108544184822 0.001717188399653573 2788/5321/54331/2767/6714/1432/2783/2782/2786/2787 10 Orf_virus R-HSA-5654708 Downstream signaling of activated FGFR3 10/1579 25/10654 0.0019259184847376773 0.00412108544184822 0.001717188399653573 5295/6464/5290/5335/2261/2247/2885/3845/3265/5781 10 Orf_virus R-HSA-937041 IKK complex recruitment mediated by RIP1 10/1579 25/10654 0.0019259184847376773 0.00412108544184822 0.001717188399653573 8737/7099/7316/329/7189/6233/7311/7334/3551/7314 10 Orf_virus R-HSA-169893 Prolonged ERK activation events 7/1579 14/10654 0.0020388036403902543 0.004355473786777866 0.0018148541609212358 5604/5594/5605/4914/4803/7529/5595 7 Orf_virus R-HSA-111996 Ca-dependent events 13/1579 38/10654 0.0022846545714660417 0.00487268130733987 0.0020303660126057142 818/815/3838/5321/5567/817/5594/5568/5566/5576/816/5580/1385 13 Orf_virus R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 28/1579 110/10654 0.0023350252986070966 0.004971960578539825 0.002071734049069954 1017/3725/1019/11065/4790/1029/5594/1027/1051/3576/3490/8881/7316/890/6774/5970/1026/5598/3552/8900/7324/6233/2353/6196/7311/3569/7314/5595 28 Poliovirus_type_1 R-HSA-2262752 Cellular responses to stress 275/1821 479/10654 1.507933729209371e-93 1.152665837931433e-90 5.083006430794773e-91 5718/1017/23165/818/3303/7014/6118/5689/3725/815/25913/81929/1019/5684/5903/5601/5720/79861/11065/4790/55706/7175/653361/5241/11258/5606/5682/64344/9631/9448/3159/246184/112399/7531/1029/1915/1783/5700/122706/7321/5707/389541/2146/25828/84962/817/6045/7422/8697/5690/10382/5594/93661/9530/3308/84335/5717/1027/9491/23198/10049/58528/10294/5925/55860/3091/830/7013/7277/348995/1051/10013/143471/50488/545/79023/5706/472/10381/5705/57122/23636/79813/10197/3337/192670/3576/3313/10808/153129/10671/1780/10762/3490/8550/8881/847/23511/7323/4306/1781/7316/10213/5709/9978/5695/10935/3305/53371/8655/6774/5970/84516/1026/1639/9261/9532/54205/832/26277/6667/5714/2289/23279/4927/9688/10121/7415/6647/7867/8994/51433/9861/79902/64223/4194/7322/5715/6119/5711/5598/9883/3552/1432/2932/5701/10524/5688/1387/10325/5687/7846/23225/3310/2908/5685/8649/5683/3309/5698/347733/5708/3320/5602/5692/65057/5686/5713/2033/23512/1021/119504/7266/6195/5699/6009/5710/6767/51143/3301/816/7428/5702/192669/10540/9531/7157/8453/51529/6648/8086/7324/10963/5719/4001/64682/29945/10393/22824/8091/57600/5609/10542/5704/6233/51434/3326/2475/5716/55004/3306/2353/1030/51343/7311/6196/367/9972/538/25906/2034/79400/10383/10670/23411/8021/55662/6117/6197/29882/5599/648/129401/5600/54583/5694/3304/3312/201163/23466/4217/26523/3456/405/5608/54386/96459/3569/64121/3297/57521/55746/5693/10641/5721/55466/140735/5696/2288/5691/5034/8480/10919/10728/829/7314/51164/996/51182/28956/5595/4193/2950/1778/23043 275 Poliovirus_type_1 R-HSA-69275 G2/M Transition 163/1821 196/10654 1.7884652256500124e-93 1.152665837931433e-90 5.083006430794773e-91 114791/10844/8454/115106/5718/1017/5689/8945/22995/55559/5684/5720/79861/440145/2305/11258/5682/22981/8636/7531/51512/10142/5700/11190/122706/5707/203068/54801/7532/84962/63943/55125/1454/22974/5690/10382/3161/95681/5717/9491/23198/6500/51400/121441/7277/79441/143471/5706/10381/5705/5116/10197/9814/653784/5048/1781/23354/7316/10213/728642/5709/80321/9978/891/993/5695/8655/9738/983/1026/1639/6790/5714/55722/4957/10121/9861/9702/5566/5715/79959/5519/84131/5711/5701/5688/5687/23291/7846/7840/5685/7283/5683/5698/347733/5708/3320/5692/22919/984/5686/5713/80097/2033/995/10426/5699/5710/22994/11064/5702/10540/5520/7157/10733/85378/79866/1069/5719/4751/5577/5704/6233/3326/27175/80254/5716/7514/7311/54930/5518/10133/10383/55835/54820/5347/29922/9662/80184/55142/5694/23332/1453/22897/7465/27229/9793/4218/5108/1022/8481/5693/5721/93323/5696/10806/55755/5691/5500/7314/5515/1778/5516 163 Poliovirus_type_1 R-HSA-453274 Mitotic G2-G2/M phases 163/1821 198/10654 4.160693347627899e-92 1.787711241697454e-89 7.883418974452864e-90 114791/10844/8454/115106/5718/1017/5689/8945/22995/55559/5684/5720/79861/440145/2305/11258/5682/22981/8636/7531/51512/10142/5700/11190/122706/5707/203068/54801/7532/84962/63943/55125/1454/22974/5690/10382/3161/95681/5717/9491/23198/6500/51400/121441/7277/79441/143471/5706/10381/5705/5116/10197/9814/653784/5048/1781/23354/7316/10213/728642/5709/80321/9978/891/993/5695/8655/9738/983/1026/1639/6790/5714/55722/4957/10121/9861/9702/5566/5715/79959/5519/84131/5711/5701/5688/5687/23291/7846/7840/5685/7283/5683/5698/347733/5708/3320/5692/22919/984/5686/5713/80097/2033/995/10426/5699/5710/22994/11064/5702/10540/5520/7157/10733/85378/79866/1069/5719/4751/5577/5704/6233/3326/27175/80254/5716/7514/7311/54930/5518/10133/10383/55835/54820/5347/29922/9662/80184/55142/5694/23332/1453/22897/7465/27229/9793/4218/5108/1022/8481/5693/5721/93323/5696/10806/55755/5691/5500/7314/5515/1778/5516 163 Poliovirus_type_1 R-HSA-8953897 Cellular responses to external stimuli 275/1821 493/10654 1.7621296566401887e-89 5.678462818523008e-87 2.5040789857518474e-87 5718/1017/23165/818/3303/7014/6118/5689/3725/815/25913/81929/1019/5684/5903/5601/5720/79861/11065/4790/55706/7175/653361/5241/11258/5606/5682/64344/9631/9448/3159/246184/112399/7531/1029/1915/1783/5700/122706/7321/5707/389541/2146/25828/84962/817/6045/7422/8697/5690/10382/5594/93661/9530/3308/84335/5717/1027/9491/23198/10049/58528/10294/5925/55860/3091/830/7013/7277/348995/1051/10013/143471/50488/545/79023/5706/472/10381/5705/57122/23636/79813/10197/3337/192670/3576/3313/10808/153129/10671/1780/10762/3490/8550/8881/847/23511/7323/4306/1781/7316/10213/5709/9978/5695/10935/3305/53371/8655/6774/5970/84516/1026/1639/9261/9532/54205/832/26277/6667/5714/2289/23279/4927/9688/10121/7415/6647/7867/8994/51433/9861/79902/64223/4194/7322/5715/6119/5711/5598/9883/3552/1432/2932/5701/10524/5688/1387/10325/5687/7846/23225/3310/2908/5685/8649/5683/3309/5698/347733/5708/3320/5602/5692/65057/5686/5713/2033/23512/1021/119504/7266/6195/5699/6009/5710/6767/51143/3301/816/7428/5702/192669/10540/9531/7157/8453/51529/6648/8086/7324/10963/5719/4001/64682/29945/10393/22824/8091/57600/5609/10542/5704/6233/51434/3326/2475/5716/55004/3306/2353/1030/51343/7311/6196/367/9972/538/25906/2034/79400/10383/10670/23411/8021/55662/6117/6197/29882/5599/648/129401/5600/54583/5694/3304/3312/201163/23466/4217/26523/3456/405/5608/54386/96459/3569/64121/3297/57521/55746/5693/10641/5721/55466/140735/5696/2288/5691/5034/8480/10919/10728/829/7314/51164/996/51182/28956/5595/4193/2950/1778/23043 275 Poliovirus_type_1 R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 109/1821 112/10654 2.052993949669814e-80 5.292618402248781e-78 2.3339299638351574e-78 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/1983/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 109 Poliovirus_type_1 R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 108/1821 111/10654 1.2297743910875324e-79 2.641965316853049e-77 1.1650494231355572e-77 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 108 Poliovirus_type_1 R-HSA-5663205 Infectious disease 225/1821 383/10654 1.1523699270930996e-78 2.1220069086042933e-76 9.357590385417652e-77 3839/6158/5718/23165/3303/6875/5689/6138/8945/6144/3837/3838/81929/6203/5434/164/1839/5684/5903/6227/9349/8065/4736/5720/6206/6194/6234/6191/55706/7175/6166/6128/5606/5682/51121/6132/9631/5604/1499/1938/3159/6159/6147/6129/6217/5700/122706/5707/2959/5430/27243/6222/6176/6152/5690/6136/6878/8106/6125/5717/4869/821/9491/23198/6500/811/6224/6146/51065/6154/348995/6141/9636/143471/6202/79023/5706/6123/5705/57122/23636/10197/6232/6134/6169/10762/6160/23511/6164/4686/7316/6155/10213/5709/6175/9978/6218/5695/6872/2960/53371/920/292/4233/3055/51534/6209/5714/6193/6714/6173/23279/6210/4927/6231/6229/9688/11224/6205/6165/8731/9861/79902/6130/5715/2962/6142/3840/6167/5711/6204/23327/9883/5701/867/5688/6228/23521/5687/116832/23225/999/5685/5683/5698/5708/3320/6455/5692/5686/5713/2534/140801/6156/5699/6235/6143/5710/6181/6124/5702/5901/6207/8086/5719/3836/6139/5609/30011/5704/6233/2885/3326/5716/7514/1025/9844/7311/6223/25873/9972/3932/1213/5610/6880/6908/3921/6188/6189/8021/7040/1794/6135/6201/129401/6161/5694/3304/6829/801/9045/6882/6187/5608/1022/5062/55746/6168/22916/5693/6208/6157/5721/6137/5696/6170/5691/200916/8480/6122/6133/2957/7314/5879/6230 225 Poliovirus_type_1 R-HSA-9010553 Regulation of expression of SLITs and ROBOs 140/1821 171/10654 2.122984616202886e-78 3.4206589628569e-76 1.5084364378283667e-76 6158/5718/5689/6138/6144/23032/6203/5684/6227/9349/4736/5720/6206/6194/6234/6191/6166/6128/5682/51121/6132/6159/6147/6129/6217/5700/122706/5707/6222/6176/6152/5690/6136/6125/5717/9491/23198/6224/6146/51065/6154/6141/26986/143471/6202/5706/6123/5705/3670/10197/6232/2935/6134/6169/6160/6164/4686/7316/6155/10213/5709/6175/9978/6218/5695/6209/5714/6193/6173/6210/6231/6229/11224/6205/6165/9861/6130/5715/6142/6167/5711/6204/5701/5688/6228/23521/5687/116832/5685/5683/5698/5708/5692/5686/5713/1981/140801/6156/5699/6235/6143/5710/6181/6124/5702/8453/6207/5719/6139/5704/6233/5716/7311/6223/25873/3921/6188/6189/9775/6135/6201/6161/5694/9045/6187/6168/22916/5693/6208/6157/5721/6137/5696/6170/5691/200916/6122/6133/7314/6230 140 Poliovirus_type_1 R-HSA-376176 Signaling by ROBO receptors 160/1821 218/10654 8.932231738753619e-77 1.2792940790281573e-74 5.641409519212813e-75 6158/5718/5689/6138/6144/25/23032/6203/5684/6227/9349/4736/5720/6206/6194/6234/6191/6166/6128/5682/51121/6132/6159/6147/6129/4690/6217/5700/122706/5707/5567/56924/6222/6176/6152/5690/6136/5578/5568/6125/5717/9491/23198/6224/6146/51065/6154/6141/26986/143471/6202/5706/6123/5705/3670/10197/6232/2935/6134/6169/6160/8829/6164/4686/7316/6155/10213/5709/6175/9978/6218/5695/6209/5714/6193/6714/6173/6210/6231/6229/11224/6205/6165/9861/5566/6130/5715/6142/6167/5711/6204/5701/5688/6228/23521/5687/116832/5685/5683/5698/5708/5692/5686/5713/5063/1981/140801/6156/5699/6235/6143/5710/6181/6124/5702/998/8453/6207/5719/6139/10487/6654/5704/6233/5716/7311/6223/25873/8440/387/1630/3921/6188/6189/9775/6135/6201/6161/5694/23332/5058/9045/6187/5062/6168/22916/5693/6208/6157/5721/6137/5696/6170/5691/200916/6122/6133/7314/5879/6230 160 Poliovirus_type_1 R-HSA-72613 Eukaryotic Translation Initiation 111/1821 119/10654 7.749415778108255e-76 9.080906307255947e-74 4.004482794429147e-74 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/1983/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/1978/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 111 Poliovirus_type_1 R-HSA-72737 Cap-dependent Translation Initiation 111/1821 119/10654 7.749415778108255e-76 9.080906307255947e-74 4.004482794429147e-74 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/1983/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/1978/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 111 Poliovirus_type_1 R-HSA-9006925 Intracellular signaling by second messengers 192/1821 305/10654 4.013406736275648e-74 4.3110677358827585e-72 1.901087401393728e-72 5295/1147/5718/2308/818/5689/5170/27161/3725/815/3643/3838/1839/5684/8841/685/5290/5720/3667/5335/2309/5682/5291/5468/2065/1822/1459/842/5700/3815/122706/572/5707/5567/389541/2146/817/10273/207/6045/5690/5578/5594/2069/4303/84335/5568/5717/1027/9491/7249/5582/23198/58528/1460/143471/5706/3708/2064/57761/5705/6199/10197/192670/2260/4615/153129/5528/2100/7316/10213/5709/1950/5695/1457/4233/8658/1026/4734/10768/5714/10645/6714/2099/1108/10818/2122/9861/64223/5566/84254/10014/5715/5519/8503/5711/1958/2932/2261/5701/5688/10325/5159/5687/5685/8649/3164/5683/5698/5708/5880/10000/145957/3084/5692/5686/5713/2534/23512/5728/5699/6009/2444/5710/6615/2264/816/3630/5702/192669/3066/3065/7157/1107/2066/23028/8975/5613/5719/5987/3654/7189/5371/208/9542/10542/5577/5704/6233/2885/10718/79109/5580/2475/5716/55004/7409/51135/8660/7311/3932/2931/5518/1386/10670/1956/5581/331/648/2549/5694/23466/26523/7874/801/64121/57521/5693/5721/5696/814/5691/5156/7314/5879/253260/28956/5595/4193/5515/3556/5516 192 Poliovirus_type_1 R-HSA-168254 Influenza Infection 129/1821 155/10654 5.822026225083605e-74 5.772762926255975e-72 2.5456632887005237e-72 3839/6158/23165/3303/6138/6144/3837/3838/81929/6203/5434/5903/6227/9349/4736/6206/6194/6234/6191/55706/7175/6166/6128/51121/6132/9631/6159/6147/6129/6217/5430/6222/6176/6152/6136/8106/6125/821/811/6224/6146/51065/6154/348995/6141/9636/6202/79023/6123/57122/23636/6232/6134/6169/10762/6160/23511/6164/6155/6175/6218/53371/6209/6193/6173/23279/6210/4927/6231/6229/9688/11224/6205/6165/79902/6130/2962/6142/3840/6167/6204/9883/6228/23521/116832/23225/3320/140801/6156/6235/6143/6181/6124/5901/6207/8086/3836/6139/6233/7514/7311/6223/25873/9972/1213/5610/3921/6188/6189/8021/7040/6135/6201/129401/6161/3304/9045/6187/55746/6168/6208/6157/6137/6170/200916/8480/6122/6133/6230 129 Poliovirus_type_1 R-HSA-72689 Formation of a pool of free 40S subunits 98/1821 101/10654 7.019513377410822e-72 6.462966245344678e-70 2.8500279878209356e-70 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/6234/27335/6191/6166/6128/51121/6132/6159/6147/8666/6129/6217/6222/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/8663/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 98 Poliovirus_type_1 R-HSA-168255 Influenza Life Cycle 122/1821 144/10654 8.59008128173331e-72 7.381743181436158e-70 3.255188696235781e-70 6158/23165/3303/6138/6144/3837/81929/6203/5434/5903/6227/9349/4736/6206/6194/6234/6191/55706/7175/6166/6128/51121/6132/9631/6159/6147/6129/6217/5430/6222/6176/6152/6136/6125/821/811/6224/6146/51065/6154/348995/6141/6202/79023/6123/57122/23636/6232/6134/6169/10762/6160/23511/6164/6155/6175/6218/53371/6209/6193/6173/23279/6210/4927/6231/6229/9688/11224/6205/6165/79902/6130/2962/6142/6167/6204/9883/6228/23521/116832/23225/3320/140801/6156/6235/6143/6181/6124/5901/6207/8086/3836/6139/6233/7514/7311/6223/25873/9972/1213/3921/6188/6189/8021/6135/6201/129401/6161/3304/9045/6187/55746/6168/6208/6157/6137/6170/200916/8480/6122/6133/6230 122 Poliovirus_type_1 R-HSA-5620912 Anchoring of the basal body to the plasma membrane 95/1821 98/10654 1.4679526495338344e-69 1.1826193532806953e-67 5.2150949391333596e-68 115106/22995/55559/79867/11258/22981/8636/7531/54903/10142/80776/11190/203068/54801/7532/55125/1454/10382/85302/51134/95681/121441/7277/79441/5116/54806/9814/91147/5048/1781/23354/80321/8766/22832/146057/8655/9738/79598/983/1639/55722/4957/10121/9702/5566/79959/132320/347240/84131/7846/7840/7283/3320/22919/27077/22994/11064/4867/79600/10540/84902/10733/1069/4751/117177/5577/80254/57545/26005/54930/5518/26123/10383/55835/54820/5347/23322/9662/80184/55142/23332/1453/22897/9793/4218/5108/261734/8481/57787/93323/10806/51259/55755/9657/1778 95 Poliovirus_type_1 R-HSA-9020702 Interleukin-1 signaling 98/1821 103/10654 2.5917825909646755e-69 1.9651810351490982e-67 8.666022285578482e-68 8454/3557/1147/5718/5689/8945/1326/5684/351/5720/4790/6283/6885/5682/5604/4215/11213/5700/122706/5707/10392/8767/5690/3553/8878/5717/9491/23198/6500/28512/23118/143471/5706/5705/246330/10197/8517/4615/7316/10213/5709/9978/5695/79155/7335/5970/4792/4793/5714/177/3146/9861/5715/64127/5711/3552/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/3656/5699/57162/5710/10454/6288/5702/5719/3654/7189/6285/5704/6233/5716/51135/7311/7334/5694/3551/5608/57161/5693/5721/5696/5691/4791/3554/7314/28511/257397/3556 98 Poliovirus_type_1 R-HSA-1257604 PIP3 activates AKT signaling 171/1821 264/10654 1.0541729165931888e-68 7.549049386047891e-67 3.328967105031123e-67 5295/1147/5718/2308/5689/5170/27161/3725/3643/1839/5684/8841/685/5290/5720/3667/2309/5682/5291/5468/2065/1822/1459/842/5700/3815/122706/572/5707/389541/2146/10273/207/6045/5690/5594/2069/4303/84335/5717/1027/9491/7249/23198/58528/1460/143471/5706/2064/57761/5705/6199/10197/192670/2260/4615/153129/5528/2100/7316/10213/5709/1950/5695/1457/4233/8658/1026/4734/5714/6714/2099/1108/10818/2122/9861/64223/10014/5715/5519/8503/5711/1958/2932/2261/5701/5688/10325/5159/5687/5685/8649/3164/5683/5698/5708/5880/10000/145957/3084/5692/5686/5713/2534/23512/5728/5699/6009/2444/5710/6615/2264/3630/5702/192669/3066/3065/7157/1107/2066/23028/8975/5719/5987/3654/7189/5371/208/9542/10542/5704/6233/2885/10718/79109/2475/5716/55004/7409/51135/8660/7311/3932/2931/5518/1386/10670/1956/331/648/2549/5694/23466/26523/7874/64121/57521/5693/5721/5696/5691/5156/7314/5879/253260/28956/5595/4193/5515/3556/5516 171 Poliovirus_type_1 R-HSA-68886 M Phase 217/1821 395/10654 2.399177187748535e-68 1.6276523131620324e-66 7.177593802682599e-67 114791/10844/4000/115106/5718/23165/4926/5689/11130/22995/55559/81929/5684/5903/5720/79861/11065/54908/440145/55706/7175/11258/5579/5682/22981/9631/246184/25936/8636/7531/10142/80776/1459/55869/1783/5700/11190/122706/7321/5707/91754/203068/54801/7532/55125/1454/8697/5690/5578/10382/9212/5594/95681/5717/9491/23198/10274/5925/121441/1460/7277/348995/23421/79441/143471/79023/5706/10381/5705/57122/23636/79980/10735/5116/10197/6232/332/1780/10762/8881/9814/653784/5885/23511/5528/5048/1781/23354/7316/10213/5709/80321/891/5695/5501/53371/8655/9738/1457/983/1639/5714/55722/4957/23279/4927/9688/10121/51433/9861/79902/9702/5566/8615/5715/79959/5519/84131/5711/9883/81565/5701/5688/699/5687/7846/23225/7840/5685/7283/5683/5698/347733/5708/3320/5692/22919/5686/5713/80097/119504/79003/8243/9126/11243/10426/5699/5710/22994/11064/51143/5702/10540/5520/10733/51529/85378/1069/8086/7324/2010/5719/4001/64682/29945/10393/4751/5577/5704/6233/51434/27175/80254/5716/7514/7311/54930/9972/5518/25906/10383/55835/54820/5347/29922/8021/29882/129401/9662/80184/55142/5694/23332/1453/22897/27229/9793/10726/5108/55746/8481/7112/5693/5721/140735/93323/5696/10806/55755/5691/8480/7314/996/5595/5515/1778/5516 217 Poliovirus_type_1 R-HSA-449147 Signaling by Interleukins 237/1821 461/10654 2.8479863539037346e-67 1.835527205090957e-65 8.094277005831668e-66 5295/8454/3557/7124/1147/5718/2308/834/1052/5689/3725/7291/8945/1326/596/5684/5601/351/9252/1072/6464/5290/5720/1437/3667/4790/6283/6885/6597/5606/2309/5682/5291/5604/4215/9049/11213/5700/7412/122706/7184/5707/10392/8767/356/3593/6775/207/5292/5451/9021/7422/29110/5690/3553/2625/1439/5594/8878/4582/5717/2919/821/9491/23198/6500/28512/3091/23118/143471/4318/5706/3383/5705/246330/301/9987/10197/8517/1438/6778/3576/4615/7534/3313/332/3662/5528/1436/4313/7316/3565/10213/5709/6175/9978/2920/5695/79155/6352/3185/6774/920/7335/5970/4792/3055/6850/1026/9261/4793/5714/3606/177/6772/8807/8651/8809/4609/3146/6647/7867/9861/5566/149233/5715/5519/64127/8503/5711/7132/5598/3552/1432/5701/867/5688/5687/6950/3558/4067/3717/23291/4088/598/836/5685/5683/5698/5708/3320/5602/5692/5686/5713/4843/2335/2534/84867/3656/595/6195/5699/57162/5710/3458/3181/10454/6288/5702/998/7157/6648/5719/4001/3654/7189/6285/5609/6654/5704/6233/2885/7525/1398/3716/5716/7409/51135/8660/2353/604/7311/6196/3594/6347/3932/5518/2185/240/1386/5896/7040/51561/6197/8835/5599/5600/4282/7334/5694/3312/1399/3551/6773/7297/5608/3569/57161/5062/4170/5693/5721/5696/5691/4791/3554/5034/51231/829/7314/28511/5595/5515/257397/3556/5516 237 Poliovirus_type_1 R-HSA-168273 Influenza Viral RNA Transcription and Replication 113/1821 134/10654 4.657434513712662e-66 2.85877766103601e-64 1.260658966117713e-64 6158/23165/6138/6144/81929/6203/5434/5903/6227/9349/4736/6206/6194/6234/6191/55706/7175/6166/6128/51121/6132/9631/6159/6147/6129/6217/5430/6222/6176/6152/6136/6125/6224/6146/51065/6154/348995/6141/6202/79023/6123/57122/23636/6232/6134/6169/10762/6160/23511/6164/6155/6175/6218/53371/6209/6193/6173/23279/6210/4927/6231/6229/9688/11224/6205/6165/79902/6130/2962/6142/6167/6204/9883/6228/23521/116832/23225/3320/140801/6156/6235/6143/6181/6124/6207/8086/6139/6233/7311/6223/25873/9972/3921/6188/6189/8021/6135/6201/129401/6161/9045/6187/55746/6168/6208/6157/6137/6170/200916/8480/6122/6133/6230 113 Poliovirus_type_1 R-HSA-156842 Eukaryotic Translation Elongation 89/1821 93/10654 1.2235707541573436e-63 7.1690122823128e-62 3.161378982033328e-62 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/1938/6159/6147/6129/1915/6217/1936/6222/6176/6152/6136/6125/1937/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/1933/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 89 Poliovirus_type_1 R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 90/1821 95/10654 3.336241829675537e-63 1.8697459645442466e-61 8.24517431590293e-62 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/6232/2935/6134/6169/6160/6164/4686/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/1981/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/5976/6187/6168/22916/6208/6157/6137/6170/200916/6122/6133/6230 90 Poliovirus_type_1 R-HSA-156902 Peptide chain elongation 86/1821 89/10654 1.284698394392332e-62 6.89990095988215e-61 3.0427067235607868e-61 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/1938/6159/6147/6129/1915/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 86 Poliovirus_type_1 R-HSA-5663202 Diseases of signal transduction 202/1821 377/10654 4.759015407093355e-61 2.453748343897334e-59 1.0820498188759628e-59 5295/8454/4000/1147/5718/2308/27044/818/5689/5170/815/5434/7276/1839/5684/4893/11052/6464/8841/685/5290/5720/3667/5335/71/2309/5682/5291/5604/1499/2065/2648/10018/10142/55869/842/5700/3815/122706/572/5707/283455/5430/8844/23462/817/207/1452/5690/5594/3280/2069/9530/4303/84335/613/5717/1027/9491/7249/23198/6500/409/10533/10013/143471/23385/5706/2064/5705/6199/10197/2260/5528/2100/4686/7316/10213/5709/673/9978/1950/5695/8315/6774/4233/9759/8658/9612/1026/5714/6772/6714/2099/4609/10818/7415/9861/64223/4089/10014/5715/2962/22938/5037/5519/8850/8503/5711/2932/2261/5701/867/5688/1387/5159/5687/7046/3717/4088/5685/6907/3164/5683/5698/5708/5880/10000/145957/3320/3084/5692/5686/5713/324/2335/2534/2033/3690/408/55294/5728/5699/1445/5710/11064/2264/816/5702/3066/3065/4296/2280/2066/5894/4087/5719/208/6654/9542/5704/6233/2885/10718/79109/2475/5716/7409/8660/7048/7311/51009/3932/2931/5518/1956/60/4140/7040/3845/2549/5694/3265/369/801/4851/22916/5693/5721/5696/11140/5691/5245/7529/5156/7314/5879/253260/5595/4193/5515/5516 202 Poliovirus_type_1 R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 80/1821 82/10654 2.265573663986353e-59 1.0816016492142256e-57 4.76962876628706e-58 114791/10844/115106/22995/55559/440145/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/653784/5048/1781/23354/728642/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/984/80097/10426/22994/11064/10540/10733/85378/1069/4751/5577/27175/80254/54930/5518/10383/55835/54820/5347/29922/9662/80184/55142/23332/1453/22897/27229/9793/5108/8481/93323/10806/55755/1778 80 Poliovirus_type_1 R-HSA-380287 Centrosome maturation 80/1821 82/10654 2.265573663986353e-59 1.0816016492142256e-57 4.76962876628706e-58 114791/10844/115106/22995/55559/440145/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/653784/5048/1781/23354/728642/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/984/80097/10426/22994/11064/10540/10733/85378/1069/4751/5577/27175/80254/54930/5518/10383/55835/54820/5347/29922/9662/80184/55142/23332/1453/22897/27229/9793/5108/8481/93323/10806/55755/1778 80 Poliovirus_type_1 R-HSA-192823 Viral mRNA Translation 84/1821 89/10654 1.2198565590822056e-58 5.615696802346296e-57 2.4764005334751543e-57 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 84 Poliovirus_type_1 R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 83/1821 88/10654 7.00038714289323e-58 3.111551388685991e-56 1.3721266995144626e-56 8454/115106/8945/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/84962/55125/1454/10382/95681/6500/121441/7277/79441/5116/9814/5048/1781/23354/7316/80321/891/8655/9738/983/1639/6790/55722/4957/10121/9702/5566/79959/84131/23291/7846/7840/7283/3320/22919/22994/11064/10540/10733/79866/1069/4751/5577/6233/80254/7311/54930/5518/10133/10383/55835/54820/5347/9662/80184/55142/23332/1453/22897/9793/4218/5108/8481/93323/10806/55755/5500/7314/1778 83 Poliovirus_type_1 R-HSA-446652 Interleukin-1 family signaling 109/1821 140/10654 7.469992271277541e-57 3.2096066792255837e-55 1.415366956663113e-55 8454/3557/1147/5718/834/5689/8945/1326/5684/351/5720/4790/6283/6885/5682/5604/4215/11213/5700/122706/5707/10392/8767/29110/5690/3553/8878/5717/9491/23198/6500/28512/23118/143471/5706/5705/246330/10197/8517/4615/7316/3565/10213/5709/9978/5695/79155/6774/7335/5970/4792/4793/5714/3606/177/8807/8809/3146/9861/5715/64127/5711/3552/5701/5688/5687/23291/4088/5685/5683/5698/5708/5692/5686/5713/84867/3656/5699/57162/5710/10454/6288/5702/5719/3654/7189/6285/5704/6233/5716/51135/7311/240/5599/7334/5694/3551/5608/57161/5693/5721/5696/5691/4791/3554/7314/28511/257397/3556 109 Poliovirus_type_1 R-HSA-927802 Nonsense-Mediated Decay (NMD) 97/1821 115/10654 8.682087521763223e-57 3.497253379860248e-55 1.5422129150500464e-55 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/6232/2935/6134/6169/6160/6164/4686/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/1981/140801/6156/6235/6143/6181/6124/5520/6207/6139/6233/23381/7311/6223/25873/5518/3921/6188/6189/23293/9775/23049/6135/6201/6161/9045/5976/6187/6168/22916/6208/6157/6137/6170/200916/6122/6133/5515/6230 97 Poliovirus_type_1 R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 97/1821 115/10654 8.682087521763223e-57 3.497253379860248e-55 1.5422129150500464e-55 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/6232/2935/6134/6169/6160/6164/4686/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/1981/140801/6156/6235/6143/6181/6124/5520/6207/6139/6233/23381/7311/6223/25873/5518/3921/6188/6189/23293/9775/23049/6135/6201/6161/9045/5976/6187/6168/22916/6208/6157/6137/6170/200916/6122/6133/5515/6230 97 Poliovirus_type_1 R-HSA-72764 Eukaryotic Translation Termination 85/1821 93/10654 2.89114373838283e-56 1.1292982662955963e-54 4.979960506305353e-55 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/2935/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 85 Poliovirus_type_1 R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 105/1821 134/10654 2.771143027408765e-55 1.050589224214676e-53 4.632870695977503e-54 5295/8454/1147/5718/5689/5170/3725/8945/9402/5684/5601/4893/6464/5290/5720/5335/4790/6885/5682/5291/5700/122706/7321/5707/84433/5690/5594/5717/4214/9491/23198/6500/23118/10892/143471/5706/3708/5705/10197/8517/7316/10213/5709/5695/7335/5970/4792/6850/10768/8915/5714/9861/7322/5715/5711/5701/5688/5687/4067/23291/5588/5685/5683/5698/5708/5602/5692/5686/5713/2534/5699/5710/10454/5702/695/5719/7189/5609/6654/5704/6233/2885/5716/7409/3702/2353/7311/3845/5599/7334/5694/3265/3551/5058/801/5062/5693/5721/5696/997/5691/7314/5879/5595/257397 105 Poliovirus_type_1 R-HSA-2408557 Selenocysteine synthesis 84/1821 93/10654 1.390862534062391e-54 5.122348018304064e-53 2.2588444162216275e-53 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 84 Poliovirus_type_1 R-HSA-5357801 Programmed Cell Death 123/1821 181/10654 6.518606620150381e-53 2.334023314826067e-51 1.0292536768658496e-51 23368/23643/4000/5718/5689/11035/3837/596/5684/5720/7186/1612/51765/5682/1499/10018/7531/5747/1029/842/5700/122706/572/5707/8737/356/7532/207/5690/5594/5717/9491/23198/355/330/2810/143471/5706/5705/841/10197/7099/7534/7316/10213/5709/5695/8655/7082/6774/54205/5714/660/8797/3146/9861/5715/5711/23604/5701/5688/10134/329/5687/999/5588/598/836/5685/5683/929/5698/5708/10000/5692/5686/5713/324/8837/5699/4137/5710/5702/7157/8626/5719/4001/3836/197259/208/5704/6233/5580/6709/5716/6093/1613/7311/7161/839/840/1630/8772/331/5599/353376/8717/7159/5694/317/8743/8795/5062/5693/5721/140735/5696/5691/7529/7314/578/5595/148022 123 Poliovirus_type_1 R-HSA-8854518 AURKA Activation by TPX2 71/1821 73/10654 1.9709685960712985e-52 6.866428433340281e-51 3.0279460650881976e-51 115106/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/22974/10382/3161/95681/121441/7277/79441/5116/9814/5048/1781/23354/80321/8655/9738/983/1639/6790/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/22994/11064/10540/10733/1069/4751/5577/80254/54930/5518/10383/55835/54820/5347/9662/80184/55142/23332/1453/22897/9793/5108/8481/93323/10806/55755/1778 71 Poliovirus_type_1 R-HSA-166166 MyD88-independent TLR4 cascade 85/1821 99/10654 3.723735137372673e-51 1.2307422030957374e-49 5.427306273093776e-50 8454/23643/1147/3665/3725/11035/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/7321/8737/10392/8767/29110/5594/6500/28512/330/23118/841/7099/8517/5528/7323/7316/79155/7335/5970/4792/9261/4793/177/3146/7867/7322/5519/64127/5598/1432/329/23291/929/5602/3656/6195/10454/6288/3661/3654/7189/6285/5609/6233/10010/2353/7311/6196/5518/1386/7187/8772/9641/6197/5599/353376/5600/7334/3551/5608/4791/51231/7314/28511/5595/5515/148022/257397/5516 85 Poliovirus_type_1 R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 85/1821 99/10654 3.723735137372673e-51 1.2307422030957374e-49 5.427306273093776e-50 8454/23643/1147/3665/3725/11035/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/7321/8737/10392/8767/29110/5594/6500/28512/330/23118/841/7099/8517/5528/7323/7316/79155/7335/5970/4792/9261/4793/177/3146/7867/7322/5519/64127/5598/1432/329/23291/929/5602/3656/6195/10454/6288/3661/3654/7189/6285/5609/6233/10010/2353/7311/6196/5518/1386/7187/8772/9641/6197/5599/353376/5600/7334/3551/5608/4791/51231/7314/28511/5595/5515/148022/257397/5516 85 Poliovirus_type_1 R-HSA-109581 Apoptosis 120/1821 178/10654 4.760584386625195e-51 1.5340983185899692e-49 6.765040970467383e-50 23368/23643/4000/5718/5689/3837/596/5684/5720/7186/1612/51765/5682/1499/10018/7531/5747/1029/842/5700/122706/572/5707/8737/356/7532/207/5690/5594/5717/9491/23198/355/2810/143471/5706/5705/841/10197/7099/7534/7316/10213/5709/5695/8655/7082/6774/54205/5714/660/8797/3146/9861/5715/5711/23604/5701/5688/10134/329/5687/999/5588/598/836/5685/5683/929/5698/5708/10000/5692/5686/5713/324/8837/5699/4137/5710/5702/7157/8626/5719/4001/3836/208/5704/6233/5580/6709/5716/6093/1613/7311/7161/839/840/1630/8772/331/5599/353376/8717/7159/5694/317/8743/8795/5062/5693/5721/140735/5696/5691/7529/7314/578/5595/148022 120 Poliovirus_type_1 R-HSA-6807070 PTEN Regulation 104/1821 140/10654 8.340722307993038e-51 2.6222417207324453e-49 1.1563517448822185e-49 5718/5689/27161/3725/5684/8841/5720/5682/5468/1822/1459/5700/122706/5707/389541/2146/10273/207/6045/5690/5594/5717/9491/23198/58528/1460/143471/5706/5705/10197/192670/153129/7316/10213/5709/5695/1457/8658/4734/5714/1108/2122/9861/64223/10014/5715/5711/1958/5701/5688/10325/5687/5685/8649/5683/5698/5708/10000/5692/5686/5713/23512/5728/5699/6009/2444/5710/6615/5702/192669/3066/3065/7157/1107/23028/8975/5719/5987/5371/208/10542/5704/6233/2475/5716/55004/7311/1386/10670/331/648/5694/23466/26523/7874/64121/57521/5693/5721/5696/5691/7314/28956/5595 104 Poliovirus_type_1 R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 99/1821 129/10654 1.1808455858177845e-50 3.6240713336169624e-49 1.5981368830616633e-49 8454/23643/1147/3665/3725/11035/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/11213/7321/8737/10392/8767/29110/5594/4214/6500/28512/330/51295/23118/246330/10333/841/7099/8517/4615/5528/7323/7316/79155/7335/5970/4792/7096/9261/4793/177/8651/3146/7867/7322/5519/64127/5598/1432/329/23291/929/5602/114609/3656/6195/57162/10454/6288/3661/695/3654/7189/6285/5609/6233/10010/51135/2353/7311/6196/5518/1386/7187/8772/9641/6197/5599/353376/5600/7334/7097/3551/5608/57161/4791/51231/7314/28511/5595/5515/148022/257397/5516 99 Poliovirus_type_1 R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 82/1821 94/10654 1.497576252501001e-50 4.387217703349523e-49 1.934667886006078e-49 8454/1147/3665/3725/11035/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/7321/8737/10392/8767/29110/5594/6500/28512/330/23118/841/8517/7098/5528/7323/7316/79155/7335/5970/4792/9261/4793/177/3146/7867/7322/5519/64127/5598/1432/329/23291/5602/3656/6195/10454/6288/3661/3654/7189/6285/5609/6233/10010/2353/7311/6196/5518/1386/7187/8772/9641/6197/5599/5600/7334/3551/5608/4791/51231/7314/28511/5595/5515/148022/257397/5516 82 Poliovirus_type_1 R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 82/1821 94/10654 1.497576252501001e-50 4.387217703349523e-49 1.934667886006078e-49 114791/10844/115106/4926/22995/55559/79861/440145/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/10381/5116/9814/653784/5048/1781/23354/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/347733/3320/22919/80097/10426/22994/11064/10540/10733/85378/1069/4751/5577/27175/80254/54930/5518/10383/55835/54820/5347/29922/9662/80184/55142/23332/1453/22897/27229/9793/5108/8481/93323/10806/55755/1778 82 Poliovirus_type_1 R-HSA-202424 Downstream TCR signaling 84/1821 98/10654 1.9437417385246753e-50 5.5677402243517925e-49 2.4552527223469586e-49 5295/8454/1147/5718/5689/5170/8945/5684/5290/5720/4790/6885/5682/5291/5700/122706/7321/5707/8767/84433/5690/5717/9491/23198/6500/3123/23118/10892/143471/5706/5705/10197/8517/3126/3115/7316/10213/5709/3122/5695/920/7335/5970/4792/8915/5714/9861/7322/5715/5711/5701/5688/5687/23291/5588/5685/5683/5698/5708/5692/5686/5713/5728/5699/5710/5702/5719/7189/5704/6233/5716/7311/3932/3127/3125/7334/5694/3551/5693/5721/5696/997/5691/7314 84 Poliovirus_type_1 R-HSA-380259 Loss of Nlp from mitotic centrosomes 68/1821 70/10654 3.9930420962792364e-50 1.0732795328628594e-48 4.7329300375316975e-49 115106/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/5048/1781/23354/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/22994/11064/10540/10733/1069/4751/5577/80254/54930/5518/10383/55835/54820/5347/9662/80184/55142/23332/1453/22897/9793/5108/8481/93323/10806/55755/1778 68 Poliovirus_type_1 R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 68/1821 70/10654 3.9930420962792364e-50 1.0732795328628594e-48 4.7329300375316975e-49 115106/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/5048/1781/23354/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/22994/11064/10540/10733/1069/4751/5577/80254/54930/5518/10383/55835/54820/5347/9662/80184/55142/23332/1453/22897/9793/5108/8481/93323/10806/55755/1778 68 Poliovirus_type_1 R-HSA-202403 TCR signaling 94/1821 119/10654 3.996696476137878e-50 1.0732795328628594e-48 4.7329300375316975e-49 5295/8454/1147/5718/5689/5170/8945/9402/5684/5290/5720/5335/4790/6885/5682/5291/4690/5700/122706/7321/5707/8767/84433/5690/5717/9491/23198/6500/3123/23118/10892/143471/5706/5705/10197/8517/3126/3115/7316/10213/5709/3122/5695/920/7335/5970/4792/8915/5714/9861/7322/5715/5711/5795/5701/5688/5687/23291/5588/5685/5683/5698/5708/5692/5686/5713/5063/5728/5699/1445/5710/5702/5719/7189/5704/6233/7454/5716/3702/7311/3932/3127/3125/7334/5694/3551/5058/5062/5693/5721/5696/997/5691/7314 94 Poliovirus_type_1 R-HSA-1169091 Activation of NF-kappaB in B cells 66/1821 67/10654 4.820354792066473e-50 1.268048434076262e-48 5.591818663192042e-49 8454/1147/5718/5689/8945/5684/5720/4790/6885/5579/5966/5682/5700/122706/5707/84433/5690/5717/9491/23198/6500/10892/143471/5706/5705/10197/8517/7316/10213/5709/5695/5970/4792/4793/8915/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/4794/5694/3551/5693/5721/5696/5691/7314 66 Poliovirus_type_1 R-HSA-5621481 C-type lectin receptors (CLRs) 104/1821 142/10654 8.348057118375703e-50 2.1521291251172564e-48 9.490422829311328e-49 8454/1147/5718/5689/5170/8945/4586/5684/9252/4893/5720/4790/6885/5682/5700/122706/7321/5707/5567/4584/84433/5690/3553/5568/4582/5717/9491/23198/6500/3384/23118/10892/29108/143471/5706/3708/5705/841/10197/8517/7316/10213/5709/5695/9020/7335/5970/4792/6850/10768/8915/5714/6714/9861/5566/7322/5715/5711/5701/5688/1387/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/5063/2534/2033/5699/5710/10454/5702/9040/5894/5719/7189/5704/6233/5580/5716/7311/5971/3845/7334/5694/3265/3551/5058/801/5062/5693/5721/5696/997/5691/4791/7314/257397 104 Poliovirus_type_1 R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 82/1821 95/10654 9.163979407698419e-50 2.2716095108698583e-48 1.0017305425419325e-48 8454/23643/1147/3725/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/11213/10392/8767/5594/4214/6500/28512/51295/23118/246330/10333/7099/8517/4615/5528/7316/79155/7335/5970/4792/7096/9261/4793/177/8651/3146/7867/5519/64127/5598/1432/23291/929/5602/114609/3656/6195/57162/10454/6288/695/3654/7189/6285/5609/6233/51135/2353/7311/6196/5518/1386/6197/5599/5600/7334/7097/3551/5608/57161/4791/51231/7314/28511/5595/5515/257397/5516 82 Poliovirus_type_1 R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 82/1821 95/10654 9.163979407698419e-50 2.2716095108698583e-48 1.0017305425419325e-48 8454/23643/1147/3725/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/11213/10392/8767/5594/4214/6500/28512/51295/23118/246330/10333/7099/8517/4615/5528/7316/79155/7335/5970/4792/7096/9261/4793/177/8651/3146/7867/5519/64127/5598/1432/23291/929/5602/114609/3656/6195/57162/10454/6288/695/3654/7189/6285/5609/6233/51135/2353/7311/6196/5518/1386/6197/5599/5600/7334/7097/3551/5608/57161/4791/51231/7314/28511/5595/5515/257397/5516 82 Poliovirus_type_1 R-HSA-5607764 CLEC7A (Dectin-1) signaling 85/1821 101/10654 1.0991535913248539e-49 2.6732244890900692e-48 1.1788340403484035e-48 8454/1147/5718/5689/5170/8945/5684/5720/4790/6885/5682/5700/122706/7321/5707/84433/5690/3553/5717/9491/23198/6500/23118/10892/29108/143471/5706/3708/5705/841/10197/8517/7316/10213/5709/5695/9020/7335/5970/4792/6850/10768/8915/5714/6714/9861/7322/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/10454/5702/9040/5719/7189/5704/6233/5580/5716/7311/5971/7334/5694/3551/801/5693/5721/5696/997/5691/4791/7314/257397 85 Poliovirus_type_1 R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 69/1821 72/10654 1.3666478490204014e-49 3.262239032198699e-48 1.4385766831793702e-48 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/9212/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 69 Poliovirus_type_1 R-HSA-5683057 MAPK family signaling cascades 160/1821 294/10654 1.9574967152355444e-49 4.587660483524758e-48 2.023058806176448e-48 5718/2308/818/5689/27161/3725/815/1839/5684/4893/6464/685/5720/1437/3667/71/2309/5682/5604/2065/5747/5700/3815/122706/5707/283455/5567/8844/817/5690/7010/1439/5594/2069/5568/2322/5717/9491/3315/23198/409/143471/5706/2064/5921/5705/10197/3337/1438/192670/2260/5596/8550/8452/5528/7316/10213/5709/673/9978/1950/5695/8315/4233/983/5597/84078/5714/6714/4609/10818/9861/5566/5715/5037/5519/5711/2261/5701/5688/5159/5687/3558/3717/5685/8649/5683/5698/5708/145957/3084/5692/5686/5713/2335/5063/2534/3690/408/5699/1445/5710/2264/816/5702/192669/4296/998/2066/5894/5719/5979/1741/1742/6654/9542/5704/1739/6233/2885/10718/6709/3716/5716/8660/7514/7311/5518/1956/1740/60/5536/5896/4140/1843/3845/5694/3265/26523/5058/369/801/7297/8202/3569/5062/5693/5721/5696/5691/5245/7529/5156/7314/5879/28956/5595/5515/284/5516 160 Poliovirus_type_1 R-HSA-2871837 FCERI mediated NF-kB activation 74/1821 82/10654 4.152294446474243e-48 9.55769203840232e-47 4.2147349644663374e-47 8454/1147/5718/5689/5170/8945/5684/5720/4790/6885/5682/5700/122706/7321/5707/84433/5690/5717/9491/23198/6500/23118/10892/143471/5706/5705/10197/8517/7316/10213/5709/5695/7335/5970/4792/8915/5714/9861/7322/5715/5711/5701/5688/5687/4067/23291/5588/5685/5683/5698/5708/5692/5686/5713/5699/5710/10454/5702/5719/7189/5704/6233/5716/7311/7334/5694/3551/5693/5721/5696/997/5691/7314/257397 74 Poliovirus_type_1 R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 76/1821 86/10654 7.885089416581342e-48 1.75239314792644e-46 7.727673838391878e-47 8454/5718/1017/5689/8945/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/9212/5717/9491/23198/6500/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/983/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/4751/5704/6233/51434/5716/51343/7311/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 76 Poliovirus_type_1 R-HSA-453276 Regulation of mitotic cell cycle 76/1821 86/10654 7.885089416581342e-48 1.75239314792644e-46 7.727673838391878e-47 8454/5718/1017/5689/8945/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/9212/5717/9491/23198/6500/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/983/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/4751/5704/6233/51434/5716/51343/7311/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 76 Poliovirus_type_1 R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 82/1821 98/10654 1.4612567538532958e-47 3.139266592861497e-46 1.384348503650491e-46 8454/23643/1147/3725/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/11213/10392/8767/5594/4214/6500/28512/51295/23118/246330/10333/7099/8517/4615/5528/7316/79155/7335/5970/4792/7096/9261/4793/177/8651/3146/7867/5519/64127/5598/1432/23291/929/5602/114609/3656/6195/57162/10454/6288/695/3654/7189/6285/5609/6233/51135/2353/7311/6196/5518/1386/6197/5599/5600/7334/7097/3551/5608/57161/4791/51231/7314/28511/5595/5515/257397/5516 82 Poliovirus_type_1 R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 82/1821 98/10654 1.4612567538532958e-47 3.139266592861497e-46 1.384348503650491e-46 8454/23643/1147/3725/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/11213/10392/8767/5594/4214/6500/28512/51295/23118/246330/10333/7099/8517/4615/5528/7316/79155/7335/5970/4792/7096/9261/4793/177/8651/3146/7867/5519/64127/5598/1432/23291/929/5602/114609/3656/6195/57162/10454/6288/695/3654/7189/6285/5609/6233/51135/2353/7311/6196/5518/1386/6197/5599/5600/7334/7097/3551/5608/57161/4791/51231/7314/28511/5595/5515/257397/5516 82 Poliovirus_type_1 R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 62/1821 63/10654 5.975169237561664e-47 1.2626218274126203e-45 5.567888504371525e-46 5718/5689/5684/5720/11065/5682/246184/5700/7321/5707/8697/5690/5717/9491/5706/5705/10197/8881/7316/10213/5709/5695/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 62 Poliovirus_type_1 R-HSA-68877 Mitotic Prometaphase 124/1821 200/10654 9.827769281280949e-47 2.0432249360598616e-45 9.010178967558087e-46 114791/10844/115106/4926/11130/22995/55559/81929/5903/79861/54908/440145/11258/22981/25936/8636/7531/10142/80776/1459/55869/1783/11190/203068/54801/7532/55125/1454/10382/9212/95681/10274/121441/1460/7277/348995/23421/79441/79023/10381/57122/79980/10735/5116/6232/332/1780/9814/653784/5885/5528/5048/1781/23354/80321/891/5501/8655/9738/1457/983/1639/55722/4957/23279/10121/79902/9702/5566/79959/5519/84131/81565/699/7846/7840/7283/347733/3320/22919/80097/79003/8243/9126/11243/10426/22994/11064/51143/10540/10733/85378/1069/4751/5577/27175/80254/7514/54930/5518/10383/55835/54820/5347/29922/9662/80184/55142/23332/1453/22897/27229/9793/10726/5108/55746/8481/140735/93323/10806/55755/5515/1778/5516 124 Poliovirus_type_1 R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 72/1821 80/10654 1.2357089623893396e-46 2.5282997659045375e-45 1.1149253795994044e-45 8454/5718/1017/5689/8945/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/5717/9491/23198/6500/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 72 Poliovirus_type_1 R-HSA-68882 Mitotic Anaphase 124/1821 201/10654 2.1527814650407867e-46 4.3358364194337094e-45 1.91200985381912e-45 4000/5718/5689/11130/81929/5684/5903/5720/79861/11065/54908/5682/246184/25936/80776/55869/1783/5700/122706/7321/5707/8697/5690/10382/9212/5717/9491/23198/10274/7277/348995/23421/143471/79023/5706/10381/5705/57122/79980/10735/10197/6232/332/1780/8881/5885/5528/5048/1781/7316/10213/5709/5695/5501/8655/5714/23279/51433/9861/79902/5715/5519/5711/81565/5701/5688/699/5687/7846/5685/5683/5698/347733/5708/5692/22919/5686/5713/119504/79003/8243/9126/11243/5699/5710/51143/5702/5520/51529/7324/2010/5719/4001/64682/29945/10393/5704/6233/51434/5716/7514/7311/5518/25906/10383/54820/5347/29882/5694/23332/9793/10726/55746/7112/5693/5721/140735/5696/5691/7314/996/5515/1778/5516 124 Poliovirus_type_1 R-HSA-168898 Toll-like Receptor Cascades 106/1821 155/10654 4.389793603048528e-46 8.705298391276234e-45 3.838847847200332e-45 8454/23643/1147/3665/3725/11035/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/11213/7184/7321/8737/10392/8767/29110/5594/6271/4214/6500/28512/330/51295/23118/246330/10333/841/7099/8517/4615/7098/7100/5528/7323/7316/79155/7335/5970/4792/7096/5289/9261/4793/6279/177/8651/3146/7867/7322/5519/64127/5598/1432/329/23291/929/5602/114609/3656/6195/57162/10454/6288/3661/695/3654/7189/6285/5609/6233/10010/51135/2353/7311/6196/5518/1386/7187/8772/9641/6197/5599/353376/5600/7334/7097/3551/30849/5608/57161/4791/51231/7314/28511/5595/5515/148022/257397/5516 106 Poliovirus_type_1 R-HSA-2555396 Mitotic Metaphase and Anaphase 124/1821 202/10654 4.6783188580189045e-46 9.136898496949042e-45 4.029174136092837e-45 4000/5718/5689/11130/81929/5684/5903/5720/79861/11065/54908/5682/246184/25936/80776/55869/1783/5700/122706/7321/5707/8697/5690/10382/9212/5717/9491/23198/10274/7277/348995/23421/143471/79023/5706/10381/5705/57122/79980/10735/10197/6232/332/1780/8881/5885/5528/5048/1781/7316/10213/5709/5695/5501/8655/5714/23279/51433/9861/79902/5715/5519/5711/81565/5701/5688/699/5687/7846/5685/5683/5698/347733/5708/5692/22919/5686/5713/119504/79003/8243/9126/11243/5699/5710/51143/5702/5520/51529/7324/2010/5719/4001/64682/29945/10393/5704/6233/51434/5716/7514/7311/5518/25906/10383/54820/5347/29882/5694/23332/9793/10726/55746/7112/5693/5721/140735/5696/5691/7314/996/5515/1778/5516 124 Poliovirus_type_1 R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 64/1821 67/10654 8.767290673948763e-46 1.6867220415999935e-44 7.438078497929823e-45 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 64 Poliovirus_type_1 R-HSA-2467813 Separation of Sister Chromatids 119/1821 190/10654 1.5409710447620695e-45 2.9210465833798644e-44 1.2881182107918229e-44 5718/5689/11130/81929/5684/5903/5720/79861/11065/54908/5682/246184/25936/80776/55869/1783/5700/122706/7321/5707/8697/5690/10382/9212/5717/9491/23198/10274/7277/348995/23421/143471/79023/5706/10381/5705/57122/79980/10735/10197/6232/332/1780/8881/5885/5528/5048/1781/7316/10213/5709/5695/5501/8655/5714/23279/51433/9861/79902/5715/5519/5711/81565/5701/5688/699/5687/7846/5685/5683/5698/347733/5708/5692/22919/5686/5713/119504/79003/8243/9126/11243/5699/5710/51143/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/7514/7311/5518/25906/10383/54820/5347/29882/5694/23332/9793/10726/55746/5693/5721/140735/5696/5691/7314/996/5515/1778/5516 119 Poliovirus_type_1 R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 80/1821 97/10654 1.7964119413245865e-45 3.3559057860396984e-44 1.47988169079371e-44 8454/23643/1147/3665/3725/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/10392/8767/5594/4214/6500/28512/51295/23118/246330/7099/8517/4615/5528/7316/79155/7335/5970/4792/5289/9261/4793/177/3146/7867/5519/64127/5598/1432/23291/929/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/51135/2353/7311/6196/5518/1386/6197/5599/353376/5600/7334/3551/30849/5608/57161/4791/51231/7314/28511/5595/5515/148022/257397/5516 80 Poliovirus_type_1 R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 78/1821 93/10654 1.9479130172788948e-45 3.5364223651725287e-44 1.5594855883329924e-44 8454/23643/1147/3665/3725/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/10392/8767/5594/4214/6500/28512/51295/23118/246330/7099/8517/4615/5528/7316/79155/7335/5970/4792/9261/4793/177/3146/7867/5519/64127/5598/1432/23291/929/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/51135/2353/7311/6196/5518/1386/6197/5599/353376/5600/7334/3551/5608/57161/4791/51231/7314/28511/5595/5515/148022/257397/5516 78 Poliovirus_type_1 R-HSA-975155 MyD88 dependent cascade initiated on endosome 78/1821 93/10654 1.9479130172788948e-45 3.5364223651725287e-44 1.5594855883329924e-44 8454/23643/1147/3665/3725/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/10392/8767/5594/4214/6500/28512/51295/23118/246330/7099/8517/4615/5528/7316/79155/7335/5970/4792/9261/4793/177/3146/7867/5519/64127/5598/1432/23291/929/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/51135/2353/7311/6196/5518/1386/6197/5599/353376/5600/7334/3551/5608/57161/4791/51231/7314/28511/5595/5515/148022/257397/5516 78 Poliovirus_type_1 R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 87/1821 112/10654 2.2750701950989832e-45 4.073007613170263e-44 1.7961080487623556e-44 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/1650/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6747/6169/6160/6164/6155/6748/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 87 Poliovirus_type_1 R-HSA-162909 Host Interactions of HIV factors 94/1821 129/10654 9.125769494501756e-45 1.611385873755173e-43 7.105862331695673e-44 5718/23165/5689/8945/3837/81929/164/5684/5903/8065/5720/55706/7175/5682/9631/3159/5700/122706/5707/5690/5717/4869/9491/23198/6500/348995/143471/79023/5706/5705/57122/23636/10197/10762/23511/7316/10213/5709/9978/5695/53371/920/292/3055/5714/23279/4927/9688/9861/79902/5715/5711/9883/5701/5688/5687/23225/5685/5683/5698/5708/5692/5686/5713/2534/5699/5710/5702/5901/8086/5719/3836/5704/6233/5716/7514/1025/9844/7311/9972/3932/8021/1794/129401/5694/5062/55746/5693/5721/5696/5691/8480/7314/5879 94 Poliovirus_type_1 R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 77/1821 92/10654 9.89934232337302e-45 1.7243584128145706e-43 7.604046734881126e-44 8454/23643/1147/3725/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/10392/8767/5594/4214/6500/28512/51295/23118/246330/7099/8517/4615/5528/7316/79155/7335/5970/4792/9261/4793/177/3146/7867/5519/64127/5598/1432/23291/929/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/51135/2353/7311/6196/5518/1386/6197/5599/353376/5600/7334/3551/5608/57161/4791/51231/7314/28511/5595/5515/148022/257397/5516 77 Poliovirus_type_1 R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 73/1821 85/10654 4.550417648491231e-44 7.617121069865406e-43 3.3589852417029274e-43 8454/1147/3725/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/10392/8767/5594/4214/6500/28512/51295/23118/246330/8517/4615/7100/5528/7316/79155/7335/5970/4792/9261/4793/177/3146/7867/5519/64127/5598/1432/23291/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/51135/2353/7311/6196/5518/1386/6197/5599/5600/7334/3551/5608/57161/4791/51231/7314/28511/5595/5515/257397/5516 73 Poliovirus_type_1 R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 73/1821 85/10654 4.550417648491231e-44 7.617121069865406e-43 3.3589852417029274e-43 8454/1147/3725/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/10392/8767/5594/4214/6500/28512/51295/23118/246330/8517/4615/7100/5528/7316/79155/7335/5970/4792/9261/4793/177/3146/7867/5519/64127/5598/1432/23291/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/51135/2353/7311/6196/5518/1386/6197/5599/5600/7334/3551/5608/57161/4791/51231/7314/28511/5595/5515/257397/5516 73 Poliovirus_type_1 R-HSA-975871 MyD88 cascade initiated on plasma membrane 73/1821 85/10654 4.550417648491231e-44 7.617121069865406e-43 3.3589852417029274e-43 8454/1147/3725/8945/1326/5601/351/9252/4790/6283/6885/5606/5604/10392/8767/5594/4214/6500/28512/51295/23118/246330/8517/4615/7100/5528/7316/79155/7335/5970/4792/9261/4793/177/3146/7867/5519/64127/5598/1432/23291/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/51135/2353/7311/6196/5518/1386/6197/5599/5600/7334/3551/5608/57161/4791/51231/7314/28511/5595/5515/257397/5516 73 Poliovirus_type_1 R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 66/1821 72/10654 4.609274192781239e-44 7.617121069865406e-43 3.3589852417029274e-43 5718/1017/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 66 Poliovirus_type_1 R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 68/1821 76/10654 1.0701833117942166e-43 1.7461598593705637e-42 7.7001863873268108e-043 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/4751/5704/6233/51434/5716/7311/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 68 Poliovirus_type_1 R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 66/1821 73/10654 4.021729839190974e-43 6.480012203396457e-42 2.8575448857409555e-42 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/4751/5704/6233/51434/5716/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 66 Poliovirus_type_1 R-HSA-9607240 FLT3 Signaling 143/1821 267/10654 4.373296829260006e-43 6.959481003600182e-42 3.0689802310596536e-42 5295/5718/818/5689/5170/815/1839/5684/4893/6464/685/5290/5720/1437/3667/71/5682/5291/5604/2065/5747/5700/3815/122706/5707/283455/8844/817/5690/7010/1439/5594/2069/2322/5717/9491/23198/409/143471/5706/2064/57761/5921/5705/10197/1438/2260/8452/5528/7316/10213/5709/673/9978/1950/5695/8315/5289/4233/3055/84078/5714/6714/10818/9861/5715/5037/5519/5711/2261/5701/5688/5159/5687/3558/3717/5685/8649/5683/5698/5708/145957/3084/5692/5686/5713/2335/2534/3690/408/5699/1445/5710/2264/816/5702/4296/2066/5894/5719/5979/1741/208/1742/6654/9542/5704/1739/6233/2885/10718/6709/3716/5716/8660/7311/5518/1956/1740/60/5536/4140/1843/3845/2549/5694/3265/369/801/30849/5693/5721/5696/5691/5245/7529/5156/7314/28956/5595/5515/284/5516 143 Poliovirus_type_1 R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 67/1821 75/10654 5.77728687125329e-43 9.081613142738403e-42 4.004794493551704e-42 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/4751/5704/6233/51434/5716/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 67 Poliovirus_type_1 R-HSA-4420097 VEGFA-VEGFR2 Pathway 79/1821 99/10654 7.25253215768024e-43 1.1263269820782926e-41 4.966857787124071e-42 5295/26999/5170/5590/4893/857/5290/5335/71/558/653361/5579/5291/1499/6461/5747/4690/5567/10006/207/7422/10458/5578/5568/3315/3708/57761/5921/1793/9261/10768/10152/6714/7867/64223/5566/8936/1432/10163/10810/10000/3320/55845/5063/2534/9475/3690/4846/3728/998/208/1398/79109/5580/2475/7409/23191/6093/3685/9844/2185/8440/3791/387/60/9564/3845/5600/3265/5058/801/3071/8877/5062/63916/5829/10787/5879/253260 79 Poliovirus_type_1 R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 71/1821 83/10654 1.224013805107265e-42 1.8782783271229341e-41 8.282800184936383e-42 8454/1147/5718/5689/8945/5684/4893/5720/4790/6885/5579/5966/5682/5700/122706/5707/84433/5690/5717/9491/23198/6500/10892/143471/5706/5705/10197/8517/7316/10213/5709/5695/5970/4792/4793/8915/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/2280/5719/5704/6233/5716/7311/4794/3845/5694/3265/3551/801/5693/5721/5696/5691/7314 71 Poliovirus_type_1 R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 58/1821 60/10654 1.8371158868950593e-42 2.7859322096561545e-41 1.228535701453043e-41 8454/1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/9020/5970/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5971/5694/5693/5721/5696/5691/4791/7314 58 Poliovirus_type_1 R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 65/1821 72/10654 2.1919020362056652e-42 3.2853043310105843e-41 1.4487479798666578e-41 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 65 Poliovirus_type_1 R-HSA-983705 Signaling by the B Cell Receptor (BCR) 84/1821 112/10654 9.703667153401893e-42 1.4377042483603493e-40 6.339964020371473e-41 5295/8454/1147/5718/5689/8945/5684/4893/5720/4790/6885/5579/5966/5682/4690/5700/122706/5707/640/84433/5690/5717/9491/23198/6500/10892/143471/5706/3708/5705/10197/8517/7316/10213/5709/5695/5970/4792/6850/10768/4793/8915/5714/9861/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/2534/5699/5710/5702/2280/695/5719/6654/30011/5704/6233/2885/5716/7409/7311/4794/3845/5694/3265/3551/801/5693/5721/5696/5691/7314 84 Poliovirus_type_1 R-HSA-5676590 NIK-->noncanonical NF-kB signaling 57/1821 59/10654 1.0667632085190006e-41 1.545008736832575e-40 6.813153549382146e-41 8454/1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/9020/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5971/5694/5693/5721/5696/5691/4791/7314 57 Poliovirus_type_1 R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 57/1821 59/10654 1.0667632085190006e-41 1.545008736832575e-40 6.813153549382146e-41 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/8668/8667/6224/51065/8662/10480/26986/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/8665/6201/1978/6187/6208/1974/1968/6230 57 Poliovirus_type_1 R-HSA-1234174 Cellular response to hypoxia 66/1821 75/10654 2.1700628675853774e-41 3.1080122625750574e-40 1.3705660216328702e-40 5718/5689/5684/5720/5682/64344/112399/5700/122706/7321/5707/84962/7422/5690/5717/9491/23198/3091/143471/5706/5705/10197/7323/7316/10213/5709/9978/5695/5714/8994/9861/7322/5715/5711/5701/5688/1387/5687/5685/5683/5698/5708/5692/5686/5713/2033/5699/5710/7428/5702/8453/5719/5704/6233/5716/7311/2034/55662/54583/5694/405/5693/5721/5696/5691/7314 66 Poliovirus_type_1 R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 61/1821 66/10654 2.497939164839301e-41 3.5382896521734714e-40 1.5603090214149482e-40 5718/5689/5684/5720/5682/64344/112399/5700/122706/7321/5707/84962/5690/5717/9491/23198/3091/143471/5706/5705/10197/7323/7316/10213/5709/9978/5695/5714/8994/9861/7322/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/7428/5702/8453/5719/5704/6233/5716/7311/2034/54583/5694/5693/5721/5696/5691/7314 61 Poliovirus_type_1 R-HSA-3371556 Cellular response to heat stress 73/1821 89/10654 2.9947988751028026e-41 4.150855645169368e-40 1.8304373430169932e-40 23165/818/3303/6118/815/81929/5903/55706/7175/9631/7531/1915/817/5594/9530/3308/84335/10049/348995/10013/545/79023/472/57122/23636/3337/3313/10808/10762/23511/3305/53371/9261/9532/23279/4927/9688/7415/79902/64223/6119/9883/2932/1387/23225/3310/3309/3320/2033/7266/6767/816/9531/8086/22824/3326/2475/3306/9972/23411/8021/6117/129401/3304/3312/3297/57521/55746/2288/8480/10728/51182/5595 73 Poliovirus_type_1 R-HSA-5687128 MAPK6/MAPK4 signaling 73/1821 89/10654 2.9947988751028026e-41 4.150855645169368e-40 1.8304373430169932e-40 5718/2308/5689/27161/3725/5684/5720/2309/5682/5700/122706/5707/5567/5690/5568/5717/9491/3315/23198/143471/5706/5705/10197/3337/192670/5596/8550/7316/10213/5709/5695/983/5597/5714/4609/9861/5566/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5063/5699/5710/5702/192669/998/5719/5704/6233/5716/7514/7311/5896/5694/26523/5058/8202/5062/5693/5721/5696/5691/7314/5879 73 Poliovirus_type_1 R-HSA-72649 Translation initiation complex formation 56/1821 58/10654 6.187885972136702e-41 8.395984229562326e-40 3.7024470082590794e-40 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/8668/8667/6224/51065/8662/10480/26986/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1974/1968/6230 56 Poliovirus_type_1 R-HSA-72702 Ribosomal scanning and start codon recognition 56/1821 58/10654 6.187885972136702e-41 8.395984229562326e-40 3.7024470082590794e-40 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/1983/8668/8667/6224/51065/8662/10480/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1974/1968/6230 56 Poliovirus_type_1 R-HSA-194138 Signaling by VEGF 81/1821 107/10654 8.30784826438264e-41 1.1155017096655441e-39 4.919120682858143e-40 5295/26999/5170/5590/4893/857/5290/5335/71/558/653361/5579/5291/1499/6461/5747/4690/5567/10006/207/7422/10458/5578/5568/3315/3708/57761/5921/8829/1793/9261/10768/10152/6714/7867/64223/5566/8936/1432/10163/10810/10000/3320/55845/5063/2534/9475/3690/4846/3728/998/208/1398/79109/5580/2324/2475/7409/23191/6093/3685/9844/2185/8440/3791/387/60/9564/3845/5600/3265/5058/801/3071/8877/5062/63916/5829/10787/5879/253260 81 Poliovirus_type_1 R-HSA-1169408 ISG15 antiviral mechanism 64/1821 72/10654 8.977224737159509e-41 1.1929528542472792e-39 5.260663437944803e-40 3839/23165/3837/3838/81929/5903/5335/55706/7175/9631/348995/9636/317649/79023/57122/23636/11274/25820/1982/7706/10762/9470/23511/7316/2317/53371/4734/3434/6772/23279/4927/9688/79902/23586/8672/3840/9883/23225/1981/1973/3661/8086/7324/3836/9246/1977/51191/4599/6233/3716/7311/9972/5610/5300/8021/9775/129401/7334/55746/5495/1974/8480/7314/5595 64 Poliovirus_type_1 R-HSA-5684996 MAPK1/MAPK3 signaling 136/1821 255/10654 1.0154579266801496e-40 1.3356380280517478e-39 5.889874118230729e-40 5718/818/5689/815/1839/5684/4893/6464/685/5720/1437/3667/71/5682/5604/2065/5747/5700/3815/122706/5707/283455/8844/817/5690/7010/1439/5594/2069/2322/5717/9491/23198/409/143471/5706/2064/5921/5705/10197/1438/2260/8452/5528/7316/10213/5709/673/9978/1950/5695/8315/4233/983/84078/5714/6714/10818/9861/5715/5037/5519/5711/2261/5701/5688/5159/5687/3558/3717/5685/8649/5683/5698/5708/145957/3084/5692/5686/5713/2335/2534/3690/408/5699/1445/5710/2264/816/5702/4296/2066/5894/5719/5979/1741/1742/6654/9542/5704/1739/6233/2885/10718/6709/3716/5716/8660/7311/5518/1956/1740/60/5536/4140/1843/3845/5694/3265/369/801/7297/3569/5693/5721/5696/5691/5245/7529/5156/7314/28956/5595/5515/284/5516 136 Poliovirus_type_1 R-HSA-69052 Switching of origins to a post-replicative state 73/1821 90/10654 1.3268653164725837e-40 1.7276054474072327e-39 7.618365453431104e-40 8454/5718/1017/4172/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/5717/9491/23198/6500/143471/5706/5705/10197/8881/7316/10213/5709/9978/4174/5695/5714/4171/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 73 Poliovirus_type_1 R-HSA-5610780 Degradation of GLI1 by the proteasome 57/1821 60/10654 1.7844743985279223e-40 2.2550857840220506e-39 9.944439372601426e-40 8454/5718/5689/8945/5684/5720/2735/5682/5700/122706/5707/5567/5690/5568/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5566/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/83737/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 57 Poliovirus_type_1 R-HSA-5610783 Degradation of GLI2 by the proteasome 57/1821 60/10654 1.7844743985279223e-40 2.2550857840220506e-39 9.944439372601426e-40 8454/5718/5689/8945/5684/5720/5682/5700/122706/5707/5567/1452/5690/5568/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5566/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 57 Poliovirus_type_1 R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 57/1821 60/10654 1.7844743985279223e-40 2.2550857840220506e-39 9.944439372601426e-40 8454/5718/5689/8945/5684/5720/5682/5700/122706/5707/5567/1452/5690/5568/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5566/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 57 Poliovirus_type_1 R-HSA-8948751 Regulation of PTEN stability and activity 62/1821 69/10654 3.5068609387837057e-40 4.388683252516696e-39 1.9353141614135934e-39 5718/5689/5684/5720/5682/1459/5700/122706/5707/10273/207/5690/5717/9491/23198/1460/143471/5706/5705/10197/7316/10213/5709/5695/1457/8658/4734/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/10000/5692/5686/5713/5728/5699/2444/5710/5702/8975/5719/5987/208/5704/6233/5716/7311/331/5694/5693/5721/5696/5691/7314 62 Poliovirus_type_1 R-HSA-5673001 RAF/MAP kinase cascade 133/1821 249/10654 6.311006150250118e-40 7.822006661223464e-39 3.449335345278405e-39 5718/818/5689/815/1839/5684/4893/6464/685/5720/1437/3667/71/5682/5604/2065/5747/5700/3815/122706/5707/283455/8844/817/5690/7010/1439/5594/2069/2322/5717/9491/23198/409/143471/5706/2064/5921/5705/10197/1438/2260/8452/5528/7316/10213/5709/673/9978/1950/5695/8315/4233/84078/5714/6714/10818/9861/5715/5037/5519/5711/2261/5701/5688/5159/5687/3558/3717/5685/8649/5683/5698/5708/145957/3084/5692/5686/5713/2335/2534/3690/408/5699/1445/5710/2264/816/5702/4296/2066/5894/5719/5979/1741/1742/6654/9542/5704/1739/6233/2885/10718/6709/3716/5716/8660/7311/5518/1956/1740/60/5536/4140/1843/3845/5694/3265/369/801/5693/5721/5696/5691/5245/7529/5156/7314/28956/5595/5515/284/5516 133 Poliovirus_type_1 R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 54/1821 56/10654 2.0753151614238533e-39 2.547696421976521e-38 1.1234788843798305e-38 5718/3303/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/3315/23198/26986/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/1981/5699/5710/5702/5719/5704/6233/5716/7311/5694/3304/3312/5693/5721/5696/5691/7314 54 Poliovirus_type_1 R-HSA-983169 Class I MHC mediated antigen processing & presentation 170/1821 371/10654 2.2823738462229612e-39 2.7754527243220725e-38 1.2239144756309822e-38 8454/23643/1147/5718/8773/5689/26224/8945/5684/6737/8065/64410/127544/5720/11065/9666/653361/55070/5682/84708/246184/54850/7319/8916/5700/122706/7321/5707/10273/9021/8697/5690/9817/10193/5717/821/9491/23198/6500/811/10533/143471/144699/5706/5705/26259/51130/10333/10197/7099/8517/4615/8881/8452/7323/54778/7316/10213/5709/9978/5695/7317/7335/7096/84861/11059/4734/84078/7337/5714/26272/8651/222235/51433/9861/7322/5715/5711/23327/55905/5701/5688/10134/55336/5687/26270/6502/23291/5685/10616/5683/929/3309/5698/5708/5692/5686/5713/55521/114609/9903/55294/5699/26190/55008/7328/79654/5710/10422/135892/7428/5702/22954/8453/83737/51529/9040/695/90933/7324/63891/5719/10075/64682/29945/9246/10393/79176/80176/8139/51191/126433/5704/6233/9870/51434/26267/5716/3685/25793/51343/7311/26091/6047/51666/90293/54461/29882/127247/7334/5694/7097/4591/3551/26268/115290/7332/90678/51725/140459/5693/5721/5696/997/51676/64320/5691/9820/7314/996 170 Poliovirus_type_1 R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 199/1821 473/10654 2.4964340489628567e-39 3.0073864384234786e-38 1.3261922148941887e-38 5295/26999/5170/3643/9402/5434/5590/1839/9252/4893/8065/6464/685/857/5290/23543/3667/5335/71/558/653361/5241/5579/4915/5291/5604/1499/2065/5340/6461/5747/4690/3815/5567/10006/5430/10273/207/7422/10458/5578/5594/10193/2069/5568/2322/3315/2241/3178/23118/23385/4318/3708/2064/57761/5921/1280/6778/2260/8829/5528/9306/1793/4686/7316/673/1950/5753/1795/3185/6774/11059/5289/4233/9261/4734/10768/10413/10152/6772/6714/2099/8651/10818/7867/3910/64223/5566/8569/2962/5519/8936/8503/5598/5795/1432/2261/867/10163/5159/4670/4067/3717/4914/10810/10000/145957/3320/3084/6455/55845/2335/5063/2534/9475/3690/4846/6195/3728/4803/8471/1445/1111/2264/3630/998/2066/83737/7072/6285/208/4145/1742/6654/9542/30011/6233/2885/7525/1398/3187/10718/79109/5580/2324/2475/7409/8660/23191/6093/3685/9844/7311/6196/3932/5518/2185/1213/8440/3791/387/1956/60/8851/5581/9564/6197/3845/5600/2549/3265/1399/5058/801/3071/1020/30849/8877/5062/3480/22916/4486/5725/11140/51231/4916/7529/5156/63916/5829/10787/7314/5879/253260/5595/5515/5516/2242/5607 199 Poliovirus_type_1 R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 151/1821 309/10654 3.92959287565209e-39 4.690041867329207e-38 2.068206776658995e-38 8454/5718/5689/26224/8945/5684/6737/8065/64410/127544/5720/11065/9666/55070/5682/84708/246184/54850/7319/8916/5700/122706/7321/5707/10273/9021/8697/5690/9817/10193/5717/9491/23198/6500/10533/143471/144699/5706/5705/26259/51130/10197/8881/8452/7323/54778/7316/10213/5709/9978/5695/7317/7335/84861/11059/4734/84078/7337/5714/26272/8651/222235/51433/9861/7322/5715/5711/23327/55905/5701/5688/55336/5687/26270/6502/23291/5685/10616/5683/5698/5708/5692/5686/5713/55521/9903/55294/5699/26190/55008/7328/79654/5710/10422/135892/7428/5702/22954/8453/83737/51529/9040/90933/7324/63891/5719/10075/64682/29945/9246/10393/79176/80176/8139/51191/126433/5704/6233/9870/51434/26267/5716/25793/51343/7311/26091/6047/51666/90293/54461/29882/127247/7334/5694/4591/26268/115290/7332/90678/51725/140459/5693/5721/5696/997/51676/64320/5691/9820/7314/996 151 Poliovirus_type_1 R-HSA-8951664 Neddylation 127/1821 234/10654 4.026747208935158e-39 4.761905644327906e-38 2.099897144205684e-38 8454/5718/51397/5689/26224/54165/8945/5684/8065/64410/5720/149951/23363/5682/23038/64344/54850/55884/5700/122706/7321/5707/9021/4738/5690/9817/5717/9491/23198/6500/3091/143471/144699/5706/5705/26259/51130/10197/28991/332/8452/8450/7323/9306/7316/10213/5709/9978/5695/84861/84078/5714/26272/222235/10980/9861/7322/5715/5711/5701/5688/55336/5687/26270/6502/7347/23291/170622/5685/90864/5683/55832/5698/5708/1642/5692/5686/5713/9903/55294/5699/26190/5710/10987/7428/5702/8453/9040/5719/79176/80176/8139/126433/5704/6233/2873/26267/5716/25793/7311/83987/51666/2034/90293/8533/54461/8835/127247/5694/51122/54939/26268/115290/54951/51725/140459/5693/5721/5696/51676/5691/150684/50813/9820/7314/51138/8451 127 Poliovirus_type_1 R-HSA-2408522 Selenoamino acid metabolism 84/1821 118/10654 8.19114565421294e-39 9.59853340752771e-38 4.232745122751185e-38 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 84 Poliovirus_type_1 R-HSA-180534 Vpu mediated degradation of CD4 51/1821 52/10654 1.8036018656387043e-38 2.075752504293116e-37 9.1536184910235e-38 5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/920/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Poliovirus_type_1 R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 51/1821 52/10654 1.8036018656387043e-38 2.075752504293116e-37 9.1536184910235e-38 5718/5689/1019/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/595/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Poliovirus_type_1 R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 65/1821 77/10654 2.2410602856743785e-38 2.5563953170214814e-37 1.1273149084901393e-37 5718/5689/5684/5720/79861/5682/51512/5700/122706/5707/63943/5690/10382/5717/9491/23198/7277/143471/5706/10381/5705/10197/7316/10213/5709/891/5695/983/1026/5714/9861/5715/5711/5701/5688/5687/7846/5685/5683/5698/347733/5708/3320/5692/22919/5686/5713/5699/5710/5702/7157/5719/5704/6233/3326/5716/7311/10383/5347/5694/5693/5721/5696/5691/7314 65 Poliovirus_type_1 R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 52/1821 54/10654 6.929255065052896e-38 7.834920858643143e-37 3.455030226342165e-37 8454/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/6790/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 52 Poliovirus_type_1 R-HSA-8878166 Transcriptional regulation by RUNX2 84/1821 121/10654 1.7816729439219959e-37 1.9970229780134372e-36 8.806438349820392e-37 8454/5718/5689/7291/25/1019/5684/8841/5720/5682/5700/122706/5707/23462/10273/207/5690/5594/3280/5717/9491/23198/6500/5925/10013/143471/5706/5705/10197/7316/10213/5709/9978/891/5695/11059/9759/983/1026/10413/5714/6772/6714/2099/9861/4089/5715/5711/2932/5701/5688/5687/6502/2908/5685/5683/5698/5708/10000/5692/5686/5713/595/55294/5699/5710/5702/5719/208/5704/6233/7525/5716/7311/367/1750/5694/5693/5721/5696/5691/10891/7314/5595 84 Poliovirus_type_1 R-HSA-69242 S Phase 99/1821 161/10654 5.302812763694282e-37 5.892522114139595e-36 2.598474494006273e-36 8454/5718/1017/4172/6118/5689/1019/5684/5720/11065/5682/246184/5700/122706/7321/5707/207/8697/5690/5717/1027/9491/23198/6500/10274/5925/143471/5706/5705/10735/10197/4149/8881/5885/7316/10213/5709/9978/4174/5753/993/5695/1026/5714/4171/4609/51433/9861/5715/6119/5711/2932/5701/5688/5687/6502/5685/5683/5698/5708/10000/5692/5686/5713/119504/1874/8243/9126/595/5699/5710/5702/51529/7324/5719/64682/29945/10393/208/5704/6233/51434/5716/51343/7311/25906/6117/29882/5981/5694/7465/1163/1022/5693/5721/5696/5691/7314/996 99 Poliovirus_type_1 R-HSA-8939902 Regulation of RUNX2 expression and activity 62/1821 73/10654 5.663524421106791e-37 6.239558101544148e-36 2.7515098402138256e-36 8454/5718/5689/7291/5684/5720/5682/5700/122706/5707/10273/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/11059/5714/6772/2099/9861/5715/5711/2932/5701/5688/5687/6502/2908/5685/5683/5698/5708/5692/5686/5713/55294/5699/5710/5702/5719/5704/6233/5716/7311/1750/5694/5693/5721/5696/5691/10891/7314 62 Poliovirus_type_1 R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 49/1821 50/10654 6.214299468323166e-37 6.788332215820814e-36 2.993507326400098e-36 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5062/5693/5721/5696/5691/7314 49 Poliovirus_type_1 R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 55/1821 60/10654 7.1776365462068145e-37 7.774767653832424e-36 3.4285039672283765e-36 8454/5718/1017/5689/1019/5684/5720/5682/5700/5707/5690/5717/1027/9491/6500/5706/5705/10197/7316/10213/5709/5753/5695/1026/5714/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/595/5699/5710/5702/5719/5704/6233/5716/7311/5694/1163/5693/5721/5696/5691/7314 55 Poliovirus_type_1 R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 52/1821 55/10654 1.0623866579474218e-36 1.1411803350785222e-35 5.032357853435156e-36 8454/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/51343/7311/5694/5693/5721/5696/5691/7314 52 Poliovirus_type_1 R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 69/1821 88/10654 1.1792976543970665e-36 1.2562931210891064e-35 5.5399802816391124e-36 5718/3303/5689/5684/5720/5682/5073/5700/122706/5707/207/5690/5578/5717/9491/3315/23198/26986/143471/5706/5705/10197/7534/7316/10213/5709/5695/9261/5714/9861/5715/5711/1432/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/1981/5699/5710/5702/5719/5704/6233/5580/5716/7514/7311/8021/54464/5600/5694/3304/3312/8570/5693/5721/5696/5691/167227/7529/7314/1994 69 Poliovirus_type_1 R-HSA-69541 Stabilization of p53 53/1821 57/10654 2.232236700569283e-36 2.3558528890367535e-35 1.0388800457962901e-35 5718/5689/5684/5720/5682/1029/5700/122706/5707/5690/5717/9491/23198/143471/5706/472/5705/10197/7316/10213/5709/5695/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314/4193 53 Poliovirus_type_1 R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/1821 52/10654 2.3028507681817763e-36 2.3558528890367535e-35 1.0388800457962901e-35 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/472/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Poliovirus_type_1 R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 50/1821 52/10654 2.3028507681817763e-36 2.3558528890367535e-35 1.0388800457962901e-35 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Poliovirus_type_1 R-HSA-69610 p53-Independent DNA Damage Response 50/1821 52/10654 2.3028507681817763e-36 2.3558528890367535e-35 1.0388800457962901e-35 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Poliovirus_type_1 R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 50/1821 52/10654 2.3028507681817763e-36 2.3558528890367535e-35 1.0388800457962901e-35 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Poliovirus_type_1 R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 65/1821 80/10654 2.369342780308298e-36 2.4047896408010992e-35 1.0604600923054133e-35 3839/23165/3837/3838/81929/5903/5335/55706/7175/9631/2316/348995/9636/317649/79023/57122/23636/11274/25820/1982/7706/10762/9470/23511/7316/2317/53371/4734/3434/6772/23279/4927/9688/79902/23586/8672/3840/9883/23225/1981/1973/3661/8086/7324/3836/9246/1977/51191/4599/6233/3716/7311/9972/5610/5300/8021/9775/129401/7334/55746/5495/1974/8480/7314/5595 65 Poliovirus_type_1 R-HSA-69620 Cell Cycle Checkpoints 142/1821 293/10654 2.642752892306458e-36 2.6613347485804875e-35 1.1735909225703021e-35 5718/1017/4172/6118/5689/11130/81929/5684/5903/5720/11065/54908/5682/246184/5883/25936/7531/51512/1029/80776/1783/5700/122706/7321/5707/7532/8697/5690/9212/5717/1027/9491/23198/2810/348995/23421/143471/545/79023/5706/472/5705/57122/79980/10197/6232/7534/332/580/1780/8881/5528/5048/1781/7316/10213/5709/4174/891/993/5695/5501/8655/983/1026/641/5714/4171/23279/51433/9861/79902/4194/5715/5519/6119/5711/3364/81565/5701/10524/5688/699/5687/5685/5683/5698/5708/5692/22919/5686/5713/995/119504/79003/11243/5699/5710/51143/1111/5702/7157/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/672/7514/7311/9025/5518/25906/54820/5347/6117/29882/7334/5694/23332/7465/9793/10726/5810/55746/5693/5721/140735/5696/5691/7529/7314/996/4193/5515/1778/5516 142 Poliovirus_type_1 R-HSA-9604323 Negative regulation of NOTCH4 signaling 51/1821 54/10654 6.016635792089659e-36 6.011971733336101e-35 2.651149186232898e-35 8454/5718/5689/5684/5720/5682/5700/5707/207/5690/5717/9491/6500/5706/5705/10197/7534/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/55294/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Poliovirus_type_1 R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 49/1821 51/10654 1.3251582673166958e-35 1.31394538967017e-34 5.794214286243044e-35 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/8668/8667/6224/51065/8662/10480/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/6204/8663/6228/8894/6235/6207/6233/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1968/6230 49 Poliovirus_type_1 R-HSA-5617833 Cilium Assembly 111/1821 201/10654 3.239836825751041e-35 3.1879005102237345e-34 1.4057950067541683e-34 115106/10694/22995/55559/79867/79861/55081/11258/22981/8636/7531/54903/10142/80776/11190/203068/54801/7532/10575/55125/1454/10382/85302/51134/95681/121441/7277/79441/10013/26146/10381/5116/54806/9814/91147/5048/1781/23354/10576/80321/8766/22832/60412/146057/8655/9738/79598/983/1639/55722/149371/4957/10121/9702/5566/79959/132320/347240/84131/6950/7846/7840/7283/347733/3320/22919/27077/22994/11064/4867/79600/10540/84902/10733/1069/4751/117177/5577/80254/57545/26005/54930/5518/26123/10383/55835/54820/5347/23322/22948/9662/80184/55142/23332/1453/8195/22897/9793/4218/5108/261734/8481/57787/140735/93323/10806/51259/55755/9657/1778/55770 111 Poliovirus_type_1 R-HSA-69615 G1/S DNA Damage Checkpoints 58/1821 68/10654 7.2280081242929e-35 7.058259448646628e-34 3.1125393836667995e-34 5718/1017/5689/5684/5720/5682/1029/5700/122706/5707/5690/5717/1027/9491/23198/143471/5706/472/5705/10197/7316/10213/5709/993/5695/1026/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/7157/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314/4193 58 Poliovirus_type_1 R-HSA-8878159 Transcriptional regulation by RUNX3 71/1821 96/10654 9.368959162307688e-35 9.080141624221511e-34 4.004145585790386e-34 7004/5718/5689/8463/5684/5720/2309/5682/1499/2648/10018/1029/5700/5707/5690/3280/5717/9491/5706/5705/10197/7316/10213/5709/5695/9759/1026/10413/5714/6714/4609/9861/4089/5715/22938/8850/5711/5701/5688/1387/5687/4088/5685/5683/5698/5708/5692/5686/5713/2033/595/5699/5710/5702/7157/5719/5704/6233/5716/7311/7040/3845/5694/4851/5693/5721/5696/5691/3676/7314/4193 71 Poliovirus_type_1 R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 66/1821 85/10654 1.2347814576697571e-34 1.1877860439823261e-33 5.237878924914917e-34 8454/5718/1017/5689/1019/5684/5720/5682/5700/5707/207/5690/5717/1027/9491/6500/5925/5706/5705/10197/4149/7316/10213/5709/5753/993/5695/1026/5714/4609/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/10000/5692/5686/5713/1874/595/5699/5710/5702/5719/208/5704/6233/5716/51343/7311/5694/7465/1163/1022/5693/5721/5696/5691/7314 66 Poliovirus_type_1 R-HSA-69202 Cyclin E associated events during G1/S transition 65/1821 83/10654 1.5619070401296413e-34 1.4913319812793389e-33 6.576450695282701e-34 8454/5718/1017/5689/1019/5684/5720/5682/5700/5707/207/5690/5717/1027/9491/6500/5925/5706/5705/10197/4149/7316/10213/5709/5753/993/5695/1026/5714/4609/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/10000/5692/5686/5713/1874/595/5699/5710/5702/5719/208/5704/6233/5716/7311/5694/7465/1163/1022/5693/5721/5696/5691/7314 65 Poliovirus_type_1 R-HSA-180585 Vif-mediated degradation of APOBEC3G 50/1821 54/10654 3.8408934639587905e-34 3.640376231649177e-33 1.6053269895802998e-33 5718/5689/5684/8065/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Poliovirus_type_1 R-HSA-195253 Degradation of beta-catenin by the destruction complex 64/1821 82/10654 7.366658968038133e-34 6.931111977957046e-33 3.0564701058321877e-33 8454/5718/5689/8945/5684/5720/7090/5682/1499/5700/122706/5707/1452/5690/5717/9491/23198/6500/143471/5706/5705/10197/5528/7316/10213/5709/9978/5695/5714/9861/5715/5519/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/324/5699/5710/5702/3065/7088/5719/5704/6233/5716/7311/5518/5694/5693/5721/5696/5691/7314/5515/5516 64 Poliovirus_type_1 R-HSA-69563 p53-Dependent G1 DNA Damage Response 56/1821 66/10654 1.890726534678889e-33 1.7533428080583366e-32 7.73186163367361e-33 5718/1017/5689/5684/5720/5682/1029/5700/122706/5707/5690/5717/1027/9491/23198/143471/5706/472/5705/10197/7316/10213/5709/5695/1026/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314/4193 56 Poliovirus_type_1 R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 56/1821 66/10654 1.890726534678889e-33 1.7533428080583366e-32 7.73186163367361e-33 5718/1017/5689/5684/5720/5682/1029/5700/122706/5707/5690/5717/1027/9491/23198/143471/5706/472/5705/10197/7316/10213/5709/5695/1026/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314/4193 56 Poliovirus_type_1 R-HSA-169911 Regulation of Apoptosis 49/1821 53/10654 2.1283017669297238e-33 1.9595578411231528e-32 8.641225219113166e-33 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5062/5693/5721/5696/5691/7314 49 Poliovirus_type_1 R-HSA-8941858 Regulation of RUNX3 expression and activity 50/1821 55/10654 3.533149687830675e-33 3.2299503174565534e-32 1.4243380600437214e-32 5718/5689/5684/5720/5682/1029/5700/5707/5690/5717/9491/5706/5705/10197/7316/10213/5709/5695/5714/6714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/2033/5699/5710/5702/5719/5704/6233/5716/7311/7040/5694/5693/5721/5696/5691/7314/4193 50 Poliovirus_type_1 R-HSA-4641258 Degradation of DVL 51/1821 57/10654 5.147878209112614e-33 4.672968317990253e-32 2.0606777115795491e-32 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/8452/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/51339/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Poliovirus_type_1 R-HSA-1632852 Macroautophagy 69/1821 95/10654 5.685366874328995e-33 5.124781748958094e-32 2.2599176386732848e-32 5563/64422/7405/65018/1459/389541/27243/79065/9140/11337/22863/8878/60673/9821/10452/51422/7249/58528/1460/10533/53632/84938/115201/153129/26100/9474/7316/83734/11152/8655/5289/1457/440738/8678/6714/64223/8408/5571/10325/8649/84971/6009/9776/55054/81631/55062/10542/6233/2475/55004/9804/7311/23710/84557/5562/11345/10670/55626/3312/5564/23192/5565/30849/64121/57521/7248/140735/7314/28956 69 Poliovirus_type_1 R-HSA-453279 Mitotic G1-G1/S phases 90/1821 149/10654 7.429286909502948e-33 6.650243629409236e-32 2.932613253751164e-32 8454/5718/1017/4172/6118/5689/25/894/1019/5684/5720/5682/1029/5700/5707/207/5690/5717/1027/9491/6500/5925/5706/5705/10197/4149/7316/10213/5709/4174/891/5753/993/5695/983/1026/5714/6714/4171/4609/9861/5715/5519/6119/5711/5701/5688/5687/4067/3717/6502/5685/5683/5698/5708/10000/5692/5686/5713/1021/1874/595/5699/5710/5702/3065/5520/5719/208/5704/6233/7298/5716/1030/7311/5518/6117/5694/7465/1163/1022/5693/5721/5696/7083/5691/7314/5515/6241/5516 90 Poliovirus_type_1 R-HSA-913531 Interferon Signaling 107/1821 199/10654 1.3597414265511447e-32 1.2087632405685693e-31 5.330383813703217e-32 3839/23165/3665/818/815/3837/3838/81929/5903/6737/51447/10379/5335/55706/7175/9631/23321/4281/7412/10410/2316/817/9021/9830/3123/23650/348995/9636/317649/79023/3383/57122/23636/11274/25820/1982/7706/3126/2634/51127/10762/3662/3115/9470/23511/7316/3122/3394/2317/53371/3663/3664/4734/3434/6772/8651/23279/4927/9688/3659/79902/23586/8672/3840/1958/9883/3717/23225/1981/1973/3458/816/3661/8086/10346/7324/3836/9246/1977/5371/51191/4599/6233/5580/3716/7311/9972/10107/5610/5300/8021/9775/3127/3125/129401/7334/3456/6773/7297/55746/5696/3660/5495/1974/8480/7314/5595 107 Poliovirus_type_1 R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 50/1821 56/10654 2.757621598622727e-32 2.434639890838832e-31 1.0736234053758275e-31 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/51009/5694/5693/5721/5696/5691/7314 50 Poliovirus_type_1 R-HSA-3700989 Transcriptional Regulation by TP53 156/1821 365/10654 8.876225862234846e-32 7.783302813891643e-31 3.4322677877599844e-31 23368/1017/6875/834/6118/2176/5170/27161/5563/3725/5434/8621/5883/7531/1029/1459/389541/6446/5430/8445/7532/207/22974/9212/835/4849/6878/1027/4869/51422/7249/355/58528/4850/2810/1460/545/472/53632/79813/192670/7534/332/153129/580/8550/9337/639/7316/891/6872/1457/54971/983/1026/54205/6790/641/25904/1108/8797/246175/64223/4194/2962/5519/112858/6119/3364/1432/5571/10524/10848/1387/4848/10325/56950/23019/1616/9099/843/8649/10000/6794/2033/995/1874/10128/5728/6009/1111/192669/3066/3065/7157/1107/8626/5371/208/10498/10542/6233/79109/2475/55004/672/55571/1025/2353/604/7311/7161/839/5562/5518/1386/55835/10670/6880/6908/10419/4513/8851/5300/6117/5600/7159/57472/3276/85456/6829/29883/26523/5564/7874/6882/317/5565/1020/5608/5810/64121/10397/1022/8795/665/57521/7248/10919/7529/7314/253260/28956/4193/5515/5516 156 Poliovirus_type_1 R-HSA-1852241 Organelle biogenesis and maintenance 136/1821 296/10654 1.0413365725933808e-31 9.069478662654512e-31 3.999443450927637e-31 115106/10694/5563/22995/55559/79867/8841/79861/55081/11258/22981/8636/7531/54903/10142/80776/11190/203068/54801/7532/10575/55125/1454/10382/85302/23408/51134/95681/51422/121441/7277/79441/10013/26146/53632/10381/5116/3313/54806/5465/9814/91147/5048/1781/23354/10576/80321/8766/22832/60412/146057/8655/9738/79598/983/1639/54205/55722/149371/4957/10121/9702/5566/79959/132320/347240/84131/1432/5571/1387/6950/7846/7840/6907/7283/347733/3320/22919/27077/22994/11064/4867/79600/10540/84902/10733/6648/1069/6256/4751/117177/10498/5577/80254/57545/26005/54930/23054/5518/26123/10383/1386/55835/54820/5347/23322/22948/6742/5600/3054/9662/80184/55142/23332/1453/8195/22897/5564/801/9793/5565/4218/5108/261734/8481/57787/140735/93323/814/10806/51259/55755/9657/10891/1778/55770 136 Poliovirus_type_1 R-HSA-4641257 Degradation of AXIN 49/1821 55/10654 1.4734379285753025e-31 1.27467214089501e-30 5.6210277741481e-31 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/8658/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 49 Poliovirus_type_1 R-HSA-9013694 Signaling by NOTCH4 62/1821 82/10654 1.9808998705076044e-31 1.702253288722868e-30 7.506567930344607e-31 8454/5718/5689/5684/5720/5682/2648/5700/5707/23462/207/5690/3280/5717/9491/6500/23385/5706/5705/10197/7534/7316/10213/5709/9978/5695/5714/9861/5715/22938/8850/5711/5701/5688/1387/5687/4088/5685/5683/5698/5708/5692/5686/5713/2033/55294/5699/5710/5702/5719/5704/6233/2324/5716/7311/5694/4851/5693/5721/5696/5691/7314 62 Poliovirus_type_1 R-HSA-3371453 Regulation of HSF1-mediated heat shock response 56/1821 69/10654 2.0261533928937767e-31 1.729610412874224e-30 7.62720691643527e-31 23165/3303/6118/81929/5903/55706/7175/9631/7531/5594/9530/3308/10049/348995/545/79023/472/57122/23636/3337/3313/10808/10762/23511/3305/53371/9261/9532/23279/4927/9688/79902/6119/9883/2932/23225/3310/3309/7266/6767/9531/8086/22824/3306/9972/23411/8021/6117/129401/3304/3312/3297/55746/8480/51182/5595 56 Poliovirus_type_1 R-HSA-5678895 Defective CFTR causes cystic fibrosis 52/1821 61/10654 2.4020704596795086e-31 2.037018962188741e-30 8.982811968330573e-31 5718/5689/5684/5720/5682/5700/122706/5707/79139/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/51009/5694/5693/5721/5696/5691/7314 52 Poliovirus_type_1 R-HSA-69239 Synthesis of DNA 77/1821 119/10654 3.379926414624911e-31 2.829042304189293e-30 1.2475463184534875e-30 8454/5718/1017/4172/6118/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/5717/9491/23198/6500/143471/5706/5705/10197/8881/7316/10213/5709/9978/4174/5695/5714/4171/51433/9861/5715/6119/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/6117/29882/5981/5694/5693/5721/5696/5691/7314/996 77 Poliovirus_type_1 R-HSA-9612973 Autophagy 77/1821 119/10654 3.379926414624911e-31 2.829042304189293e-30 1.2475463184534875e-30 5563/64422/7405/65018/1459/1915/389541/27243/79065/9140/11337/22863/8878/60673/9821/10452/51422/7249/58528/1080/1460/10533/10013/53632/84938/5116/6035/115201/153129/26100/9474/7316/83734/11152/8655/5289/1457/440738/8678/6714/64223/8408/5571/3920/10325/8649/3320/84971/6009/9776/55054/81631/55062/10542/6233/3326/2475/55004/9804/7311/23710/84557/5562/11345/10670/55626/3312/5564/23192/5565/30849/64121/57521/7248/140735/7314/28956 77 Poliovirus_type_1 R-HSA-1236974 ER-Phagosome pathway 62/1821 83/10654 6.548678960799848e-31 5.445965922884519e-30 2.4015528956413706e-30 23643/1147/5718/8773/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/811/143471/5706/5705/10333/10197/7099/8517/4615/7316/10213/5709/5695/7096/5714/9861/5715/5711/5701/5688/5687/5685/5683/929/5698/5708/5692/5686/5713/114609/5699/5710/5702/695/5719/5704/6233/5716/7311/5694/7097/3551/5693/5721/5696/5691/7314 62 Poliovirus_type_1 R-HSA-5658442 Regulation of RAS by GAPs 55/1821 68/10654 9.865783527046455e-31 8.151919850232615e-30 3.5948199086404095e-30 5718/5689/5684/4893/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5921/5705/10197/8452/7316/10213/5709/9978/5695/84078/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/3845/5694/3265/5693/5721/5696/5691/7314 55 Poliovirus_type_1 R-HSA-69206 G1/S Transition 81/1821 131/10654 1.065364413879031e-30 8.746845410764783e-30 3.8571691819958216e-30 8454/5718/1017/4172/6118/5689/1019/5684/5720/5682/5700/5707/207/5690/5717/1027/9491/6500/5925/5706/5705/10197/4149/7316/10213/5709/4174/891/5753/993/5695/983/1026/5714/4171/4609/9861/5715/5519/6119/5711/5701/5688/5687/6502/5685/5683/5698/5708/10000/5692/5686/5713/1874/595/5699/5710/5702/3065/5719/208/5704/6233/7298/5716/7311/5518/6117/5694/7465/1163/1022/5693/5721/5696/7083/5691/7314/5515/6241/5516 81 Poliovirus_type_1 R-HSA-450294 MAP kinase activation 53/1821 64/10654 1.2021217997653043e-30 9.80718354365492e-30 4.3247553089491304e-30 8454/1147/3725/8945/1326/5601/9252/4790/6885/5606/5604/10392/8767/5594/6500/23118/8517/5528/7316/79155/7335/9261/7867/5519/64127/5598/1432/23291/5602/3656/6195/10454/3654/7189/5609/6233/2353/7311/6196/5518/1386/6197/5599/5600/7334/3551/5608/51231/7314/5595/5515/257397/5516 53 Poliovirus_type_1 R-HSA-5688426 Deubiquitination 134/1821 297/10654 2.9873844052869048e-30 2.4218481122105788e-29 1.0679825083448718e-29 5718/5689/23032/5684/5720/7186/56957/6885/51651/5682/2648/5700/122706/7321/5707/8737/10392/8767/84196/4738/7375/5690/2625/9817/57506/4303/10445/91833/5717/9491/23198/409/1080/330/3091/143471/5706/5705/11274/4287/27005/10197/7706/8517/580/7316/10213/5709/993/5695/79155/7417/4792/9738/8658/983/5714/8678/2099/9100/4609/7415/9861/4194/23586/4089/5715/64127/8850/7128/5711/5701/4798/5688/9097/329/5687/7046/6502/7347/9099/4088/5685/5683/5698/5708/5692/5686/5713/324/2033/408/64135/5728/5699/5710/10454/8473/5702/7157/10869/8975/4087/63891/5719/7189/5704/6233/5716/672/7048/9804/7311/84282/367/114548/7187/387/60/23770/7040/8607/7345/3054/1540/5694/7874/5693/5721/5696/5691/5886/7314/4193 134 Poliovirus_type_1 R-HSA-68949 Orc1 removal from chromatin 56/1821 71/10654 3.353898747351442e-30 2.7019846783350057e-29 1.1915166602432757e-29 8454/5718/1017/4172/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/4174/5695/5714/4171/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 56 Poliovirus_type_1 R-HSA-5387390 Hh mutants abrogate ligand secretion 50/1821 59/10654 6.241079032429206e-30 4.996739672547358e-29 2.203453859111979e-29 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/51009/5694/5693/5721/5696/5691/7314 50 Poliovirus_type_1 R-HSA-162906 HIV Infection 114/1821 233/10654 9.511429460698986e-30 7.568044799284564e-29 3.337343670420697e-29 5718/23165/6875/5689/8945/3837/81929/5434/164/5684/5903/8065/5720/55706/7175/5682/9631/3159/5700/122706/5707/2959/5430/27243/5690/6878/5717/4869/9491/23198/6500/348995/143471/79023/5706/5705/57122/23636/10197/10762/23511/4686/7316/10213/5709/9978/5695/6872/2960/53371/920/292/3055/51534/5714/23279/4927/9688/8731/9861/79902/5715/2962/5711/23327/9883/5701/5688/5687/23225/5685/5683/5698/5708/5692/5686/5713/2534/5699/5710/5702/5901/8086/5719/3836/5704/6233/5716/7514/1025/9844/7311/9972/3932/6880/6908/8021/1794/129401/5694/6829/6882/1022/5062/55746/22916/5693/5721/5696/5691/8480/2957/7314/5879 114 Poliovirus_type_1 R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 45/1821 51/10654 1.1687042539500766e-28 9.242084560378213e-28 4.075558909480409e-28 5718/5689/5684/5720/5682/51582/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/5694/5693/5721/5696/5691 45 Poliovirus_type_1 R-HSA-5610787 Hedgehog 'off' state 72/1821 113/10654 1.2968236847654527e-28 1.0192717863796759e-27 4.494767585194766e-28 8454/5718/5689/8945/5684/5720/55081/2735/5682/54903/5700/122706/5707/5567/1452/5690/10382/5568/5717/9491/23198/6500/7277/143471/5706/10381/5705/10197/7316/10213/5709/9978/5695/5727/5714/9861/5566/5715/5711/2932/5701/5688/5687/7846/5685/5683/5698/347733/5708/5692/5686/5713/5699/5710/5702/83737/5719/5577/5704/6233/5716/7311/10383/23432/23322/5694/8481/5693/5721/5696/5691/7314 72 Poliovirus_type_1 R-HSA-69306 DNA Replication 77/1821 127/10654 2.028794352044984e-28 1.584918739264233e-27 6.989148007044921e-28 8454/5718/1017/4172/6118/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/5717/9491/23198/6500/143471/5706/5705/10197/8881/7316/10213/5709/9978/4174/5695/5714/4171/51433/9861/5715/6119/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/6117/29882/5981/5694/5693/5721/5696/5691/7314/996 77 Poliovirus_type_1 R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 44/1821 50/10654 6.157342370188271e-28 4.7812134428751095e-27 2.10841146474424e-27 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/5694/5693/5721/5696/5691 44 Poliovirus_type_1 R-HSA-8848021 Signaling by PTK6 46/1821 54/10654 7.9040036545097435e-28 6.0644408992042015e-27 2.6742869507739736e-27 120892/1017/1839/1019/4893/685/2065/207/9021/2069/55620/1027/202559/3091/2064/5921/10657/1793/7316/1950/5753/6774/867/6421/2908/145957/3084/595/2066/9542/6233/1398/10718/9844/10656/7311/2034/387/1956/9564/3845/3265/63916/5829/7314/5879 46 Poliovirus_type_1 R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 46/1821 54/10654 7.9040036545097435e-28 6.0644408992042015e-27 2.6742869507739736e-27 120892/1017/1839/1019/4893/685/2065/207/9021/2069/55620/1027/202559/3091/2064/5921/10657/1793/7316/1950/5753/6774/867/6421/2908/145957/3084/595/2066/9542/6233/1398/10718/9844/10656/7311/2034/387/1956/9564/3845/3265/63916/5829/7314/5879 46 Poliovirus_type_1 R-HSA-5358346 Hedgehog ligand biogenesis 51/1821 65/10654 2.0693138077906883e-27 1.5783109457054422e-26 6.960009070115053e-27 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/51009/5694/5693/5721/5696/5691/5034/7314 51 Poliovirus_type_1 R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 48/1821 59/10654 3.479367520813341e-27 2.638179255487292e-26 1.1633798521604983e-26 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 48 Poliovirus_type_1 R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 66/1821 102/10654 6.627672447986458e-27 4.9959472429558743e-26 2.2031044148431442e-26 8454/7124/1147/5718/5689/8945/5684/5720/7186/5682/5700/122706/5707/356/5690/5717/9491/23198/6500/330/143471/5706/5705/10197/7316/10213/5709/5695/9020/5714/9861/5715/5711/7132/5701/5688/329/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5971/7187/958/5694/5693/5721/5696/5691/4791/959/7314 66 Poliovirus_type_1 R-HSA-5632684 Hedgehog 'on' state 59/1821 85/10654 1.1947205548663483e-26 8.953458111760017e-26 3.9482809034750806e-26 5718/5689/5684/5720/2735/5682/5700/122706/5707/1452/5690/5717/9491/23198/409/79577/143471/5706/5705/10197/8452/7316/10213/5709/9978/5695/5727/5714/9861/5715/8405/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/408/5699/5710/5702/83737/5719/5704/6233/5716/7311/23432/5694/5693/5721/5696/5691/7314 59 Poliovirus_type_1 R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 56/1821 78/10654 1.4864645549338514e-26 1.1075449776356848e-25 4.8840332197400654e-26 1147/3665/351/7186/4790/6283/7321/8737/9140/29110/57506/4214/28512/9636/54476/841/7706/8517/84166/7323/9474/7316/5970/4792/4793/177/3146/23586/7322/7128/1387/843/2033/64135/6288/83737/3661/9246/7189/6285/51191/6233/10010/7311/84282/79671/7187/8772/5300/9641/1540/3551/3456/4791/7314/28511 56 Poliovirus_type_1 R-HSA-1227986 Signaling by ERBB2 43/1821 50/10654 1.9317154916128316e-26 1.4310237176373219e-25 6.310504328317781e-26 5295/1839/4893/8065/6464/685/5290/5335/2065/10273/207/5578/10193/2069/2064/7316/1950/5753/6714/10000/145957/3320/3084/2534/2066/208/4145/6654/9542/6233/2885/7525/10718/5580/7311/387/1956/5581/3845/2549/3265/11140/7314 43 Poliovirus_type_1 R-HSA-1236975 Antigen processing-Cross presentation 64/1821 99/10654 4.3045333023632136e-26 3.1705962438549615e-25 1.3981642004668483e-25 23643/1147/5718/8773/5689/5684/5720/653361/5682/5700/122706/5707/5690/5717/9491/23198/811/143471/5706/5705/10333/10197/7099/8517/4615/7316/10213/5709/5695/7096/5714/9861/5715/5711/5701/5688/5687/5685/5683/929/5698/5708/5692/5686/5713/114609/5699/5710/5702/695/5719/5704/6233/5716/3685/7311/5694/7097/3551/5693/5721/5696/5691/7314 64 Poliovirus_type_1 R-HSA-448424 Interleukin-17 signaling 53/1821 72/10654 4.553243112516909e-26 3.334733165928577e-25 1.4705450243774706e-25 8454/1147/3725/8945/1326/5601/9252/4790/6885/5606/5604/10392/8767/5594/6500/23118/8517/5528/7316/79155/7335/9261/7867/5519/64127/5598/1432/23291/5602/3656/6195/10454/3654/7189/5609/6233/2353/7311/6196/5518/1386/6197/5599/5600/7334/3551/5608/51231/7314/5595/5515/257397/5516 53 Poliovirus_type_1 R-HSA-68867 Assembly of the pre-replicative complex 51/1821 68/10654 8.918318490421523e-26 6.49475284415443e-25 2.8640451887169924e-25 5718/4172/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/4174/5695/5714/4171/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Poliovirus_type_1 R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 45/1821 55/10654 9.281754681314131e-26 6.6839004381083325e-25 2.9474551766595896e-25 1147/834/596/351/4790/6885/842/10392/8767/10910/9051/835/330/23118/29108/841/8517/7316/7335/5970/64127/7128/1432/329/837/598/10628/3656/10454/83737/3654/7189/6233/3326/4210/7311/114548/5600/7334/1540/3551/5608/4791/7314/257397 45 Poliovirus_type_1 R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 45/1821 55/10654 9.281754681314131e-26 6.6839004381083325e-25 2.9474551766595896e-25 3303/79861/5241/11258/1783/10382/93661/10294/55860/830/7277/10381/3337/10671/1780/4306/1781/3305/8655/84516/1639/832/2289/10121/7846/2908/347733/3320/51143/3301/10540/10963/3326/3306/367/10383/3304/3312/55466/140735/2288/10728/829/51164/1778 45 Poliovirus_type_1 R-HSA-5633007 Regulation of TP53 Activity 85/1821 160/10654 1.2966056244538977e-25 9.285136944005968e-25 4.0945440772228353e-25 23368/1017/6875/6118/5170/5563/5883/1029/1459/6446/8445/207/22974/9212/6878/51422/1460/545/472/53632/79813/580/8550/639/7316/6872/1457/54971/983/6790/641/1108/64223/4194/5519/112858/6119/3364/1432/5571/10524/10848/56950/1616/9099/10000/6794/2033/1111/3066/3065/7157/1107/8626/5371/208/6233/79109/2475/672/7311/7161/5562/5518/6880/6908/10419/8851/5300/6117/5600/7159/5564/7874/6882/5565/1020/5608/5810/10919/7314/253260/4193/5515/5516 85 Poliovirus_type_1 R-HSA-4608870 Asymmetric localization of PCP proteins 49/1821 64/10654 1.6212430561269101e-25 1.1545758559931421e-24 5.091429196327604e-25 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/23513/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 49 Poliovirus_type_1 R-HSA-72766 Translation 124/1821 291/10654 3.0289031206891184e-25 2.1451956717408096e-24 9.459847803193315e-25 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/1938/6159/6147/8666/6129/1915/6217/1936/6222/1650/1983/6176/6152/6136/8668/8667/6125/1937/7818/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/65003/6232/2935/6134/6747/6169/6160/55699/6164/6155/6748/8661/6175/6218/9669/1933/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/1978/6161/9045/6187/6168/6208/6157/6137/6170/7284/1974/200916/6122/6133/1968/6230 124 Poliovirus_type_1 R-HSA-5619084 ABC transporter disorders 54/1821 77/10654 7.675548335364193e-25 5.4064381444177294e-24 2.3841220023564367e-24 5718/5689/5684/5720/5682/5700/122706/5707/79139/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/19/335/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/51009/5694/5693/5721/5696/5691/7314 54 Poliovirus_type_1 R-HSA-351202 Metabolism of polyamines 46/1821 59/10654 1.2572799020098984e-24 8.807792357014995e-24 3.884045463874973e-24 5718/5689/5684/5720/5682/51582/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/6303/5694/5693/5721/5696/5691 46 Poliovirus_type_1 R-HSA-5358351 Signaling by Hedgehog 80/1821 149/10654 1.4149192995276764e-24 9.85854582211446e-24 4.3474049601419364e-24 8454/5718/5689/8945/5684/5720/55081/2735/5682/54903/5700/122706/5707/5567/1452/5690/10382/5568/5717/9491/23198/6500/409/79577/7277/143471/5706/10381/5705/10197/8452/7316/10213/5709/9978/5695/5727/5714/7415/9861/5566/5715/8405/5711/2932/5701/5688/5687/7846/5685/5683/5698/347733/5708/5692/5686/5713/408/5699/5710/5702/83737/5719/5577/5704/6233/5716/7311/51009/10383/23432/23322/5694/8481/5693/5721/5696/5691/5034/7314 80 Poliovirus_type_1 R-HSA-73887 Death Receptor Signalling 77/1821 141/10654 2.525456510980308e-24 1.750168517555708e-23 7.717863700788718e-24 7124/1147/4804/57142/81858/8841/7186/56957/4790/6885/5584/10018/7531/572/8737/8767/55072/356/4974/7375/835/9530/8878/355/330/23421/23118/23385/841/27005/8517/4615/6453/7316/5970/4792/4168/65078/23229/8797/50649/7128/7132/329/84894/9099/843/836/10616/396/8837/4803/11108/10454/3066/3065/3654/7189/6654/4099/6233/7409/7311/26574/387/8772/331/5599/8717/1540/3551/7185/8743/8795/7314/5879/257397 77 Poliovirus_type_1 R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 91/1821 185/10654 3.688177238224237e-24 2.542278320893605e-23 1.1210896192744656e-23 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/10436/6222/1454/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/55781/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/83732/26168/3921/6188/6189/6135/6201/6161/1453/9045/6187/4691/6168/6208/6157/6137/6170/200916/6122/6133/6230 91 Poliovirus_type_1 R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 90/1821 182/10654 4.078545095950896e-24 2.7964067173833536e-23 1.2331547322583897e-23 23165/7020/81929/5893/6670/5903/55706/7175/5241/9631/5468/1029/8204/6045/9212/4869/10274/348995/79023/57122/23636/10735/8517/332/3183/10762/5465/5885/23511/4306/53371/1655/5970/4792/3190/9759/9612/8856/6790/641/2099/23279/4927/9688/79902/9883/1387/10401/10521/1616/1789/23225/2908/2033/23512/8243/9126/7022/142/7428/3066/3065/7157/1107/1069/6256/8086/7329/5987/5371/672/367/9972/6612/7155/5914/25942/8021/9641/6117/6294/648/129401/55746/7421/4791/8480/10891/10062/4193 90 Poliovirus_type_1 R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 32/1821 33/10654 6.192182295523994e-24 4.223133851285941e-23 1.8623104648192468e-23 1147/351/4790/6283/6885/10392/8767/28512/23118/8517/7316/7335/5970/4792/4793/177/3146/64127/3656/10454/6288/3654/7189/6285/6233/7311/7334/3551/4791/7314/28511/257397 32 Poliovirus_type_1 R-HSA-4086400 PCP/CE pathway 59/1821 92/10654 7.010321019376399e-24 4.7559493652506204e-23 2.097270554273272e-23 5718/5689/5684/5720/5579/5682/5700/122706/5707/5690/5578/5717/9491/5582/23198/409/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5881/5711/5701/5688/5687/5685/5683/5698/5708/5880/5692/5686/5713/5699/5710/5702/5719/23513/5704/6233/5716/7311/1213/387/5694/5693/5721/5696/5691/4920/7314/5879 59 Poliovirus_type_1 R-HSA-5689880 Ub-specific processing proteases 101/1821 220/10654 9.802540328863323e-24 6.615431666965875e-23 2.917261933086908e-23 5718/5689/23032/5684/5720/7186/6885/51651/5682/2648/5700/122706/5707/8737/84196/7375/5690/2625/9817/4303/91833/5717/9491/23198/409/1080/330/3091/143471/5706/5705/11274/27005/10197/8517/7316/10213/5709/993/5695/7417/4792/9738/8658/5714/8678/9100/4609/9861/4194/23586/4089/5715/5711/5701/5688/9097/329/5687/7046/6502/9099/4088/5685/5683/5698/5708/5692/5686/5713/408/64135/5728/5699/5710/10454/5702/7157/10869/8975/4087/63891/5719/7189/5704/6233/5716/9804/7311/367/23770/8607/1540/5694/7874/5693/5721/5696/5691/7314/4193 101 Poliovirus_type_1 R-HSA-71291 Metabolism of amino acids and derivatives 142/1821 372/10654 4.298432620021578e-23 2.885770649587403e-22 1.2725622888221776e-22 6158/5718/5689/6138/6144/6203/5684/6227/9349/4736/5720/6206/6194/6234/6191/6166/6128/5682/51121/6132/6159/6147/51582/6129/6217/5700/3028/122706/5707/25828/6222/6176/6152/5690/6136/6125/5717/1468/9491/23198/6224/6146/51065/6154/6141/143471/6202/5706/6123/5705/10197/6232/6134/6169/6160/6164/6155/10213/5709/6175/6218/5695/9380/10165/5409/6209/5714/6193/6173/6210/6231/6229/11224/6205/6165/9861/6130/5715/6142/6167/5711/6204/5701/5688/6228/23521/5687/116832/23474/5685/5683/5698/5708/5692/5686/5713/445/6999/140801/6156/5699/6235/6143/5710/6181/6124/5702/6207/5719/6139/5704/6233/5716/7311/6223/25873/1644/10157/3921/6188/6189/29968/6135/6201/6161/6303/5694/9045/6187/6168/5693/6208/6157/5721/6137/5696/6170/5691/200916/6122/6133/6230 142 Poliovirus_type_1 R-HSA-2990846 SUMOylation 90/1821 188/10654 7.534711863160408e-23 5.032250565602988e-22 2.2191133930224275e-22 23165/7020/81929/5893/6670/5903/55706/7175/5241/9631/5468/1029/8204/6045/9212/4869/10274/348995/79023/57122/23636/10735/8517/332/3183/10762/5465/5885/23511/4306/53371/1655/5970/4792/3190/9759/9612/8856/6790/641/2099/23279/4927/9688/79902/9883/1387/10401/10521/1616/1789/23225/2908/2033/23512/8243/9126/7022/142/7428/3066/3065/7157/1107/1069/6256/8086/7329/5987/5371/672/367/9972/6612/7155/5914/25942/8021/9641/6117/6294/648/129401/55746/7421/4791/8480/10891/10062/4193 90 Poliovirus_type_1 R-HSA-8868773 rRNA processing in the nucleus and cytosol 92/1821 195/10654 9.196422158922357e-23 6.110406269510783e-22 2.6945566824840335e-22 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/10436/6222/1454/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/55781/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/1736/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/83732/26168/3921/6188/6189/6135/6201/6161/1453/9045/6187/4691/6168/6208/6157/6137/6170/200916/6122/6133/6230 92 Poliovirus_type_1 R-HSA-69002 DNA Replication Pre-Initiation 55/1821 85/10654 1.2588860786286094e-22 8.32155977103732e-22 3.669627435678538e-22 5718/1017/4172/6118/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/4174/5695/5714/4171/9861/5715/6119/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/6117/5694/5693/5721/5696/5691/7314 55 Poliovirus_type_1 R-HSA-5689603 UCH proteinases 61/1821 102/10654 2.5480560520080815e-22 1.6757368627747026e-21 7.389636241054587e-22 5718/5689/5684/5720/5682/5700/122706/5707/4738/5690/10445/5717/9491/23198/143471/5706/5705/10197/580/7316/10213/5709/5695/5714/9861/5715/5711/5701/4798/5688/5687/7046/7347/5685/5683/5698/5708/5692/5686/5713/5699/5710/8473/5702/5719/5704/6233/5716/7048/7311/60/7040/8607/7345/3054/5694/5693/5721/5696/5691/7314 61 Poliovirus_type_1 R-HSA-165159 mTOR signalling 35/1821 40/10654 2.883667485041154e-22 1.886826085389872e-21 8.320493945617008e-22 5563/6194/389541/207/84335/51422/7249/58528/53632/6198/153129/64223/5571/10325/8649/6794/1981/6009/1977/208/10542/1975/2475/55004/5562/10670/92335/1978/5564/5565/64121/57521/7248/7529/28956 35 Poliovirus_type_1 R-HSA-2219528 PI3K/AKT Signaling in Cancer 60/1821 101/10654 9.155094362926385e-22 5.960058905965712e-21 2.6282567549070963e-21 5295/1147/2308/5170/1839/685/5290/3667/2309/5291/2065/842/3815/572/207/2069/4303/84335/1027/7249/2064/6199/2260/2100/1950/4233/1026/6714/2099/10818/64223/8503/2932/2261/5159/3164/5880/10000/145957/3084/2534/5728/2264/2066/208/9542/2885/10718/79109/2475/7409/8660/3932/2931/1956/2549/5156/5879/253260/4193 60 Poliovirus_type_1 R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 29/1821 30/10654 1.1753729450335336e-21 7.613345357528768e-21 3.357320234425328e-21 7124/1147/81858/7186/56957/6885/8737/55072/7375/330/23118/27005/8517/7316/7128/7132/329/9099/10616/10454/6233/7311/331/8717/1540/3551/7185/7314/257397 29 Poliovirus_type_1 R-HSA-72312 rRNA processing 93/1821 205/10654 1.7279744924530937e-21 1.113679560386019e-20 4.91108539960353e-21 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6159/6147/6129/6217/3028/10436/6222/1454/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/55781/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/1736/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/83732/26168/3921/6188/6189/6135/6201/6161/1453/9045/6187/4691/6168/6208/6157/6137/6170/200916/6122/6133/6230 93 Poliovirus_type_1 R-HSA-168638 NOD1/2 Signaling Pathway 32/1821 36/10654 6.474488226557965e-21 4.1520474248921476e-20 1.830962892035246e-20 1147/834/6885/842/10392/8767/835/330/23118/841/8517/7316/7335/64127/7128/1432/329/837/3656/10454/83737/3654/7189/6233/7311/5600/7334/1540/3551/5608/7314/257397 32 Poliovirus_type_1 R-HSA-5619115 Disorders of transmembrane transporters 83/1821 176/10654 1.2356229260894372e-20 7.884742335293488e-20 3.477000417343909e-20 5718/23165/5689/81929/5684/5903/5720/55706/7175/5682/9631/6559/5700/122706/5707/79139/5690/5717/9491/23198/1080/348995/143471/79023/5706/5705/57122/23636/10197/10762/23511/7316/10213/5709/19/335/5695/53371/3098/5714/23279/4927/9688/7415/9861/79902/5715/5711/9883/5701/5688/5687/10999/23225/5685/5683/682/5698/5708/5692/5686/5713/5699/5710/5702/8086/5719/5704/6233/5716/7311/51009/9972/8021/129401/5694/55746/5693/5721/5696/5691/8480/7314 83 Poliovirus_type_1 R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 53/1821 86/10654 2.063615359741198e-20 1.310344925471135e-19 5.778337019757568e-20 5295/26999/25/1072/3984/5290/5335/71/51517/5291/5747/4690/10006/4627/10458/4771/5594/2268/3708/1793/3055/6850/10768/10152/4641/6714/8936/10163/4067/10810/3320/55845/2534/998/695/8976/2885/7525/1398/3326/5580/7454/7409/23191/9844/60/5581/5058/3071/63916/10787/5879/5595 53 Poliovirus_type_1 R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 31/1821 35/10654 3.416855301399258e-20 2.158983570344923e-19 9.52064944662332e-20 23165/81929/5903/55706/7175/9631/7884/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/1977/9972/8021/129401/55746/22916/8480 31 Poliovirus_type_1 R-HSA-69481 G2/M Checkpoints 79/1821 168/10654 1.327866484220664e-19 8.349365356880175e-19 3.681889096170263e-19 5718/1017/4172/6118/5689/5684/5720/5682/5883/7531/51512/5700/122706/5707/7532/5690/5717/9491/23198/2810/143471/545/5706/472/5705/10197/7534/580/7316/10213/5709/4174/891/993/5695/983/641/5714/4171/9861/5715/6119/5711/3364/5701/10524/5688/5687/5685/5683/5698/5708/5692/5686/5713/995/5699/5710/1111/5702/7157/5719/5704/6233/5716/672/7311/9025/6117/7334/5694/7465/5810/5693/5721/5696/5691/7529/7314 79 Poliovirus_type_1 R-HSA-159227 Transport of the SLBP independent Mature mRNA 30/1821 34/10654 1.7960336984913578e-19 1.1212907743362725e-18 4.94464920290382e-19 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/1977/9972/8021/129401/55746/22916/8480 30 Poliovirus_type_1 R-HSA-168253 Host Interactions with Influenza Factors 34/1821 42/10654 1.800676418057474e-19 1.1212907743362725e-18 4.94464920290382e-19 3839/23165/3837/3838/81929/5903/55706/7175/9631/8106/348995/9636/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/3840/9883/23225/8086/3836/9972/5610/8021/7040/129401/55746/8480 34 Poliovirus_type_1 R-HSA-168276 NS1 Mediated Effects on Host Pathways 33/1821 40/10654 2.020661981875237e-19 1.2522275454986445e-18 5.522051974760264e-19 3839/23165/3837/3838/81929/5903/55706/7175/9631/8106/348995/9636/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/3840/9883/23225/8086/3836/9972/5610/8021/129401/55746/8480 33 Poliovirus_type_1 R-HSA-933542 TRAF6 mediated NF-kB activation 24/1821 24/10654 3.406310422298668e-19 2.1008297293507097e-18 9.26420361642549e-19 1147/351/7186/4790/6283/57506/4214/28512/7706/8517/5970/4792/4793/177/3146/23586/64135/6288/7189/6285/84282/3551/4791/28511 24 Poliovirus_type_1 R-HSA-195258 RHO GTPase Effectors 122/1821 327/10654 5.170013440429285e-19 3.1734034879587376e-18 1.3994021342515361e-18 26999/5170/11130/25/81929/5590/5903/1072/3984/79861/54908/71/51517/653361/5579/1499/25936/7531/5747/80776/4690/1783/10006/4627/2316/7532/10458/4771/5578/10382/9212/5594/3985/6722/1027/1080/2810/7277/348995/23421/79023/10381/57122/79980/6232/7534/332/1780/5528/5048/1781/5501/8655/5289/5585/10152/6279/6714/23279/79902/5519/8936/1432/81565/10163/699/7846/999/10810/347733/5880/22919/55845/5063/9475/995/3895/79003/11243/51143/998/23028/695/10788/1742/8976/2885/5580/7454/23191/7514/6093/57120/367/5518/10383/54820/5347/387/60/5300/5600/23332/5058/801/3071/9793/10726/30849/5586/5062/55746/140735/5500/7529/10787/5879/4221/5595/5515/1778/5516 122 Poliovirus_type_1 R-HSA-2559583 Cellular Senescence 86/1821 195/10654 5.498589969801352e-19 3.3590912185184565e-18 1.4812863974520983e-18 1017/7014/3725/25913/1019/5601/11065/4790/5606/9448/3159/246184/1029/7321/2146/6045/8697/5594/1027/5925/7013/1051/50488/472/79813/192670/3576/3490/8550/8881/7316/6774/5970/1026/9261/26277/6667/7867/51433/4194/5598/3552/1432/10524/5602/65057/23512/1021/119504/6195/192669/7157/51529/7324/4001/64682/29945/10393/8091/5609/6233/51434/2353/1030/51343/7311/6196/25906/6197/29882/5599/648/5600/23466/4217/26523/3456/5608/54386/3569/10919/7314/996/5595/4193/23043 86 Poliovirus_type_1 R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 29/1821 33/10654 9.400999008968681e-019 5.71598477479275e-18 2.5206253549369854e-18 23165/3303/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/7514/9972/8021/129401/3304/55746/8480 29 Poliovirus_type_1 R-HSA-3858494 Beta-catenin independent WNT signaling 70/1821 146/10654 4.350088582339075e-18 2.632518395603318e-17 1.1608835356872254e-17 5718/5689/27161/815/5684/5720/6885/5579/5682/1499/5700/122706/5707/5690/5578/5717/9491/5582/23198/409/143471/5706/3708/5705/10197/192670/7316/10213/5709/5695/5714/9861/5715/5881/5711/5701/5688/5687/5685/5683/5698/5708/5880/5692/5686/5713/5699/5710/5702/192669/5719/23513/5704/6233/5716/7311/1213/387/5593/3845/5694/26523/801/5693/5721/5696/5691/4920/7314/5879 70 Poliovirus_type_1 R-HSA-382556 ABC-family proteins mediated transport 56/1821 103/10654 6.4619562050699774e-18 3.8922717515585053e-017 1.7164074524042244e-17 5718/5689/5684/5720/1965/5682/5700/122706/5707/79139/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/335/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/8894/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/51009/5694/5693/5721/5696/5691/7314/1968 56 Poliovirus_type_1 R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 27/1821 31/10654 2.5408579542192277e-17 1.516280510642863e-16 6.686468300576917e-17 23165/3837/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/3836/9972/8021/129401/55746/8480 27 Poliovirus_type_1 R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 27/1821 31/10654 2.5408579542192277e-17 1.516280510642863e-16 6.686468300576917e-17 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/7514/9972/8021/129401/55746/8480 27 Poliovirus_type_1 R-HSA-180746 Nuclear import of Rev protein 28/1821 33/10654 2.7068351549695668e-17 1.6078850298413695e-16 7.09042436906896e-17 23165/3837/81929/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/9972/8021/129401/55746/8480 28 Poliovirus_type_1 R-HSA-69618 Mitotic Spindle Checkpoint 58/1821 112/10654 3.468406661917491e-17 2.0508147647759843e-16 9.043648466612483e-17 11130/81929/5903/11065/54908/246184/25936/80776/1783/7321/8697/9212/348995/23421/79023/57122/79980/6232/332/1780/8881/5528/5048/1781/5501/8655/23279/51433/79902/5519/81565/699/22919/119504/79003/11243/51143/51529/7324/64682/29945/10393/51434/7514/5518/25906/54820/5347/29882/23332/9793/10726/55746/140735/996/5515/1778/5516 58 Poliovirus_type_1 R-HSA-8878171 Transcriptional regulation by RUNX1 95/1821 239/10654 3.906924022860936e-17 2.2995548244144963e-16 1.0140538199206466e-16 5718/6595/5689/27161/25/894/5684/5720/1437/5579/6597/5682/1459/5700/122706/5707/640/6045/9021/5690/2625/5717/9491/23198/1460/4005/143471/5706/6598/5705/10197/6599/192670/7316/10213/5709/5695/7082/1457/10413/5714/6714/2099/9861/5715/8850/5711/5701/5688/1387/5687/3558/5588/5685/5683/8289/5698/5708/5692/5686/5713/10138/2033/1021/6605/6602/595/50943/5699/5710/3458/5702/192669/3065/83737/5719/5371/5704/6233/5716/7311/7161/25942/648/3276/5694/6601/23466/26523/1022/5693/5721/5696/5691/7314 95 Poliovirus_type_1 R-HSA-450302 activated TAK1 mediates p38 MAPK activation 23/1821 24/10654 4.050250863088076e-17 2.3730788011456956e-16 1.0464762995538572e-16 6885/5606/10392/8767/23118/8517/7316/7335/9261/7867/64127/1432/3656/10454/3654/7189/6233/7311/5600/7334/5608/7314/257397 23 Poliovirus_type_1 R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 21/1821 21/10654 7.031302256459707e-17 4.101062718812924e-16 1.808479742075848e-16 1147/11035/4790/8737/29110/23220/28512/147945/8517/4615/7098/5970/4792/4793/1660/3661/81030/3551/4791/28511/148022 21 Poliovirus_type_1 R-HSA-438064 Post NMDA receptor activation events 47/1821 81/10654 9.229656383803596e-17 5.359021206631908e-16 2.3632121608600956e-16 818/5170/5563/815/3838/4893/79861/5567/817/10382/5594/5568/51422/7277/53632/10381/10645/6714/5566/84254/5571/27330/7846/347733/3084/6195/4137/816/2066/5613/1741/1742/5577/1739/6196/5562/10383/1740/6197/3845/3265/5564/801/5565/814/5879/5595 47 Poliovirus_type_1 R-HSA-3232142 SUMOylation of ubiquitinylation proteins 30/1821 38/10654 9.293674174026752e-17 5.371993726601114e-16 2.36893276090368e-16 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/7428/8086/7329/5987/5371/9972/8021/129401/55746/8480/4193 30 Poliovirus_type_1 R-HSA-177243 Interactions of Rev with host cellular proteins 29/1821 36/10654 1.1248389831087722e-16 6.4728457554786045e-16 2.85438463758805e-16 23165/3837/81929/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/7514/9972/8021/129401/55746/8480 29 Poliovirus_type_1 R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 56/1821 108/10654 1.1332175378200442e-16 6.492077361111276e-16 2.86286535870327e-16 5295/7124/2308/1052/7291/596/2309/7412/7184/356/3593/207/5292/5451/9021/7422/3553/2625/4582/3091/4318/3383/301/6778/3576/332/3662/4313/3565/6774/1026/3606/6772/8651/4609/149233/3552/3717/598/3320/4843/2335/595/6288/7157/3716/2353/604/6347/240/7040/51561/3312/7297/3569/4170 56 Poliovirus_type_1 R-HSA-157118 Signaling by NOTCH 93/1821 235/10654 1.183875408388683e-16 6.752280537225718e-16 2.9776093177917505e-16 8454/5718/1999/5689/27161/3725/5684/8841/5720/7090/5682/5584/2648/55869/5700/5707/23462/207/5690/3280/23220/5717/9491/6500/409/3091/51548/10013/23385/5706/5705/10197/192670/7534/7316/10213/5709/9978/1950/4854/5695/9759/9612/5714/6772/4609/9861/10014/5715/22938/8850/5711/5701/5688/1387/5687/4088/5685/6907/5683/5698/5708/5692/5686/5713/2033/408/595/55294/5699/5710/5702/192669/3066/3065/7157/7088/83737/5719/5704/6233/2324/5716/7311/1956/5694/26523/4851/5693/5721/5696/5691/7314 93 Poliovirus_type_1 R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 28/1821 34/10654 1.284160864703986e-16 7.29199715684334e-16 3.2156126452128574e-16 7321/9140/29110/57506/9636/54476/7706/84166/7323/9474/7316/23586/7322/7128/64135/83737/3661/9246/51191/6233/7311/84282/79671/7187/5300/9641/1540/7314 28 Poliovirus_type_1 R-HSA-75893 TNF signaling 32/1821 43/10654 1.816283407845434e-16 1.0268374178564756e-15 4.528130379670058e-16 7124/1147/81858/7186/56957/6885/8737/55072/7375/9530/330/23118/841/27005/8517/7316/7128/7132/329/9099/10616/10454/6233/7311/8772/331/8717/1540/3551/7185/7314/257397 32 Poliovirus_type_1 R-HSA-166208 mTORC1-mediated signalling 22/1821 23/10654 2.294575569412416e-16 1.2859599604228716e-15 5.670804610904827e-16 6194/389541/84335/58528/6198/153129/64223/10325/8649/1981/6009/1977/10542/1975/2475/55004/10670/1978/64121/57521/7529/28956 22 Poliovirus_type_1 R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 22/1821 23/10654 2.294575569412416e-16 1.2859599604228716e-15 5.670804610904827e-16 11065/246184/7321/8697/8881/7316/891/983/51433/119504/51529/7324/64682/29945/10393/6233/51434/7311/25906/29882/7314/996 22 Poliovirus_type_1 R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 39/1821 61/10654 3.7109520347592303e-16 2.070743364850497e-15 9.131529272134813e-16 26999/25/1072/3984/71/51517/5747/4690/10006/4627/10458/4771/5594/1793/6850/10152/4641/8936/10163/10810/3320/55845/998/695/8976/2885/1398/3326/7454/7409/23191/9844/60/5058/3071/63916/10787/5879/5595 39 Poliovirus_type_1 R-HSA-5213460 RIPK1-mediated regulated necrosis 20/1821 20/10654 4.151630660477106e-16 2.2967604812682357e-15 1.0128215751785126e-15 11035/7186/8737/356/355/330/841/7316/8797/329/8837/197259/6233/7311/8772/331/8717/8743/8795/7314 20 Poliovirus_type_1 R-HSA-5218859 Regulated Necrosis 20/1821 20/10654 4.151630660477106e-16 2.2967604812682357e-15 1.0128215751785126e-15 11035/7186/8737/356/355/330/841/7316/8797/329/8837/197259/6233/7311/8772/331/8717/8743/8795/7314 20 Poliovirus_type_1 R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 23/1821 25/10654 4.2424301502072817e-16 2.336962591289396e-15 1.0305498340584491e-15 1147/2308/5170/2309/842/572/207/4303/84335/1027/7249/6199/1026/64223/2932/3164/10000/208/79109/2475/2931/253260/4193 23 Poliovirus_type_1 R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 28/1821 35/10654 5.37567008032563e-16 2.948612227038186e-15 1.3002740619824593e-15 23165/81929/5903/55706/7175/9631/91754/348995/79023/57122/23636/10762/23511/891/53371/983/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 28 Poliovirus_type_1 R-HSA-180910 Vpr-mediated nuclear import of PICs 27/1821 33/10654 6.270763184353049e-16 3.410554322629148e-15 1.503980510571018e-15 23165/81929/5903/55706/7175/9631/3159/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/3836/9972/8021/129401/55746/8480 27 Poliovirus_type_1 R-HSA-389356 CD28 co-stimulation 27/1821 33/10654 6.270763184353049e-16 3.410554322629148e-15 1.503980510571018e-15 5295/5170/1326/9402/5290/207/57761/9020/6714/64223/8503/4067/10000/5063/2534/998/208/2885/7525/79109/2475/7409/3932/5058/5062/5879/253260 27 Poliovirus_type_1 R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK 25/1821 29/10654 6.730972865014783e-16 3.630219256487053e-15 1.6008479837515893e-15 5563/389541/51422/7249/58528/53632/153129/64223/5571/10325/8649/6794/6009/10542/2475/55004/5562/10670/92335/5564/5565/64121/57521/7248/28956 25 Poliovirus_type_1 R-HSA-8863795 Downregulation of ERBB2 signaling 25/1821 29/10654 6.730972865014783e-16 3.630219256487053e-15 1.6008479837515893e-15 1839/8065/685/2065/10273/207/10193/2069/2064/7316/1950/10000/145957/3320/3084/2066/208/4145/9542/6233/10718/7311/1956/11140/7314 25 Poliovirus_type_1 R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 31/1821 42/10654 8.031421453021457e-16 4.313542605393608e-15 1.9021787651892926e-15 23165/81929/5903/55706/7175/9631/7884/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/1977/9972/8021/129401/55746/22916/8480 31 Poliovirus_type_1 R-HSA-2980766 Nuclear Envelope Breakdown 35/1821 52/10654 1.1305242060475965e-15 6.046662662221377e-15 2.6664471337222196e-15 4000/23165/81929/5903/55706/7175/5579/9631/91754/5578/348995/79023/57122/23636/10762/23511/891/53371/983/23279/4927/9688/79902/9883/23225/8086/2010/4001/9972/5347/8021/129401/55746/7112/8480 35 Poliovirus_type_1 R-HSA-1250196 SHC1 events in ERBB2 signaling 21/1821 22/10654 1.2969257842099313e-15 6.908005520027279e-15 3.046280658866303e-15 1839/4893/6464/685/2065/5578/2069/2064/1950/145957/3084/2066/6654/9542/2885/10718/5580/1956/5581/3845/3265 21 Poliovirus_type_1 R-HSA-4615885 SUMOylation of DNA replication proteins 32/1821 45/10654 1.6144967119286185e-15 8.564140994551395e-15 3.776600495739459e-15 23165/81929/5903/55706/7175/9631/9212/348995/79023/57122/23636/332/10762/23511/53371/6790/23279/4927/9688/79902/9883/10401/23225/8086/7329/9972/6612/7155/8021/129401/55746/8480 32 Poliovirus_type_1 R-HSA-199418 Negative regulation of the PI3K/AKT network 55/1821 110/10654 1.6948765643304141e-15 8.953671686155343e-15 3.94837508515282e-15 5295/3643/1839/685/5290/3667/5291/2065/3815/207/5594/2069/2064/57761/2260/4615/5528/2100/1950/4233/6714/2099/10818/5519/8503/2261/5159/5880/10000/145957/3084/2534/5728/2264/3630/2066/3654/7189/208/9542/2885/10718/7409/51135/8660/3932/5518/1956/2549/5156/5879/5595/5515/3556/5516 55 Poliovirus_type_1 R-HSA-176033 Interactions of Vpr with host cellular proteins 28/1821 36/10654 2.0253578920584827e-15 1.0655862542299527e-14 4.699004346773709e-15 23165/81929/5903/55706/7175/9631/3159/348995/79023/57122/23636/10762/23511/53371/292/23279/4927/9688/79902/9883/23225/8086/3836/9972/8021/129401/55746/8480 28 Poliovirus_type_1 R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 49/1821 92/10654 2.3000306289867826e-15 1.2051786507170582e-14 5.314576549648535e-15 1017/6875/6118/5563/5883/1459/8445/22974/9212/6878/51422/1460/545/472/53632/580/8550/7316/6872/1457/6790/641/4194/112858/6119/3364/1432/5571/10524/6794/1111/7157/6233/672/7311/5562/6880/6908/8851/5300/6117/5600/5564/6882/5565/1020/5810/7314/4193 49 Poliovirus_type_1 R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 19/1821 19/10654 2.450199338189467e-15 1.268396364227399e-14 5.5933529597223094e-15 5295/4893/6464/5290/5335/7316/1950/867/3320/6654/6233/2885/7311/1956/3845/2549/3265/11140/7314 19 Poliovirus_type_1 R-HSA-176412 Phosphorylation of the APC/C 19/1821 19/10654 2.450199338189467e-15 1.268396364227399e-14 5.5933529597223094e-15 11065/246184/7321/8697/8881/891/983/51433/119504/51529/7324/64682/29945/10393/51434/25906/5347/29882/996 19 Poliovirus_type_1 R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 19/1821 19/10654 2.450199338189467e-15 1.268396364227399e-14 5.5933529597223094e-15 5295/4893/6464/5290/5335/7316/1950/867/3320/6654/6233/2885/7311/1956/3845/2549/3265/11140/7314 19 Poliovirus_type_1 R-HSA-165054 Rev-mediated nuclear export of HIV RNA 27/1821 34/10654 2.550480070299967e-15 1.315027524246663e-14 5.7989862651030835e-15 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/7514/9972/8021/129401/55746/8480 27 Poliovirus_type_1 R-HSA-8939211 ESR-mediated signaling 87/1821 223/10654 3.2137259718349317e-15 1.6503955289622418e-14 7.2778864533062e-15 5295/5170/27161/3725/3838/596/5434/5590/1839/4893/6464/685/857/5290/7090/5241/2309/5747/7031/8204/5430/207/5451/2625/5594/2069/6722/1027/3315/10274/4318/10735/5481/192670/5885/2100/4313/1950/1655/6667/7033/2289/6714/2099/4609/2962/8850/8503/10524/1387/10000/3320/2033/8243/4846/9126/595/192669/3065/2066/23028/2771/208/10498/3326/7514/1025/2353/1386/6908/1956/5536/3169/3845/858/3276/7392/3265/26523/801/8202/8877/3480/2288/10728/2957/5595 87 Poliovirus_type_1 R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 30/1821 41/10654 3.5212384376071095e-015 1.801141407172843e-14 7.942643092346864e-15 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/1977/9972/8021/129401/55746/22916/8480 30 Poliovirus_type_1 R-HSA-6806003 Regulation of TP53 Expression and Degradation 28/1821 37/10654 6.971583000941005e-15 3.551925094155319e-14 1.5663219556930073e-14 1017/5170/1029/6446/207/472/639/7316/983/64223/4194/5519/1616/9099/10000/7157/208/6233/79109/2475/7311/5518/7874/7314/253260/4193/5515/5516 28 Poliovirus_type_1 R-HSA-5357905 Regulation of TNFR1 signaling 26/1821 33/10654 1.2007840245206542e-14 6.093742549634344e-14 2.6872083433118663e-14 7124/1147/81858/7186/56957/8737/55072/7375/330/841/27005/8517/7316/7128/7132/329/9099/10616/6233/7311/331/8717/1540/3551/7185/7314 26 Poliovirus_type_1 R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 21/1821 23/10654 1.2505342170531128e-14 6.321327865809656e-14 2.7875685333691682e-14 5601/6885/10392/8767/23118/8517/7316/7335/64127/5602/3656/10454/3654/7189/5609/6233/7311/5599/7334/7314/257397 21 Poliovirus_type_1 R-HSA-5675482 Regulation of necroptotic cell death 18/1821 18/10654 1.445386586854304e-14 7.277747306465618e-14 3.2093287701534716e-14 7186/8737/356/355/330/841/7316/8797/329/8837/6233/7311/8772/331/8717/8743/8795/7314 18 Poliovirus_type_1 R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 25/1821 31/10654 1.4641734943813708e-14 7.31519238084336e-14 3.2258412360911477e-14 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 25 Poliovirus_type_1 R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 25/1821 31/10654 1.4641734943813708e-14 7.31519238084336e-14 3.2258412360911477e-14 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/129401/55746/8480 25 Poliovirus_type_1 R-HSA-1643713 Signaling by EGFR in Cancer 22/1821 25/10654 1.6121910292808156e-14 7.962123512425178e-14 3.5111238387241e-14 5295/1839/4893/6464/685/5290/5335/2069/7316/1950/867/3320/6654/6233/2885/7311/1956/3845/2549/3265/11140/7314 22 Poliovirus_type_1 R-HSA-429947 Deadenylation of mRNA 22/1821 25/10654 1.6121910292808156e-14 7.962123512425178e-14 3.5111238387241e-14 9924/5073/4849/4850/255967/26986/10605/9337/25904/246175/4848/23019/1981/1973/1977/1975/55571/9775/57472/85456/29883/1974 22 Poliovirus_type_1 R-HSA-937041 IKK complex recruitment mediated by RIP1 22/1821 25/10654 1.6121910292808156e-14 7.962123512425178e-14 3.5111238387241e-14 23643/1147/11035/7321/8737/330/7099/8517/7323/7316/7335/7322/329/929/7189/6233/7311/353376/7334/3551/7314/148022 22 Poliovirus_type_1 R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 51/1821 103/10654 3.0018601477067975e-14 1.4768693627458253e-13 6.512673683252996e-14 5295/3643/1839/685/5290/3667/5291/2065/3815/207/5594/2069/2064/2260/4615/5528/2100/1950/4233/6714/2099/10818/5519/8503/2261/5159/5880/145957/3084/2534/2264/3630/2066/3654/7189/9542/2885/10718/7409/51135/8660/3932/5518/1956/2549/5156/5879/5595/5515/3556/5516 51 Poliovirus_type_1 R-HSA-6804757 Regulation of TP53 Degradation 27/1821 36/10654 3.130017294563406e-14 1.534065510529365e-13 6.764896294033378e-14 1017/5170/1029/6446/207/472/7316/983/64223/4194/5519/1616/9099/10000/7157/208/6233/79109/2475/7311/5518/7874/7314/253260/4193/5515/5516 27 Poliovirus_type_1 R-HSA-388841 Costimulation by the CD28 family 40/1821 70/10654 3.728770492030598e-14 1.8206004409952428e-13 8.028453212506072e-14 5295/5170/1326/9402/5290/207/3123/57761/3126/3115/5528/3122/9020/920/6714/64223/5519/8503/4067/10000/5063/2534/1445/998/208/2885/7525/79109/2475/7409/3932/5518/3127/3125/5058/5062/5879/253260/5515/5516 40 Poliovirus_type_1 R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 19/1821 20/10654 4.11158885088826e-14 1.9999388787905535e-13 8.819296840038374e-14 1147/11035/7321/8737/330/8517/7098/7323/7316/7335/7322/329/7189/6233/7311/7334/3551/7314/148022 19 Poliovirus_type_1 R-HSA-4085377 SUMOylation of SUMOylation proteins 26/1821 34/10654 4.274426081365286e-14 2.0713290296540804e-13 9.134111926938086e-14 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/7329/9972/8021/129401/55746/8480 26 Poliovirus_type_1 R-HSA-166520 Signaling by NTRKs 50/1821 101/10654 5.425687927490827e-14 2.6193676923354593e-13 1.1550843606722047e-13 5295/9252/4893/6464/5290/3667/5335/4915/5291/5604/5594/5528/673/1795/6774/9261/6714/10818/7867/5519/5598/1432/4914/2534/6195/4803/6654/2885/1398/8660/6196/5518/1213/387/8851/6197/3845/5600/2549/3265/1399/1020/51231/4916/7529/5879/5595/5515/5516/5607 50 Poliovirus_type_1 R-HSA-5673000 RAF activation 25/1821 32/10654 5.607229632369294e-14 2.6969100731806047e-13 1.1892788693949017e-13 818/815/4893/5604/8844/817/5528/673/8315/6714/5519/3717/816/4296/5894/5518/4140/3845/3265/369/801/5245/7529/5515/5516 25 Poliovirus_type_1 R-HSA-9614085 FOXO-mediated transcription 38/1821 65/10654 5.928638700508765e-14 2.8408978754482526e-13 1.252774368332903e-13 2308/857/2309/65018/10018/356/7532/207/4303/1027/2810/4287/6720/7534/847/1026/4089/8850/9314/1387/4088/2908/10628/10000/6794/2033/3630/3066/3065/6648/4087/91584/208/604/23411/25942/7529/10891 38 Poliovirus_type_1 R-HSA-70171 Glycolysis 40/1821 71/10654 7.143832237080083e-14 3.4105184272578617e-13 1.5039646814905442e-13 23165/81929/5903/2597/55706/7175/9631/5315/5567/5568/348995/79023/57122/23636/3099/10762/23511/5528/53371/5230/3098/23279/4927/9688/79902/5566/5519/9883/2023/226/23225/8086/9972/5518/8021/129401/55746/8480/5515/5516 40 Poliovirus_type_1 R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 42/1821 77/10654 7.743425153562269e-14 3.669586405493296e-13 1.6182080429270995e-13 23165/81929/5893/5903/55706/7175/9631/1029/6045/10274/348995/79023/57122/23636/10735/10762/5885/23511/53371/641/23279/4927/9688/79902/9883/23225/8243/9126/142/1069/8086/7329/5371/672/9972/6612/8021/6117/648/129401/55746/8480 42 Poliovirus_type_1 R-HSA-9009391 Extra-nuclear estrogen signaling 42/1821 77/10654 7.743425153562269e-14 3.669586405493296e-13 1.6182080429270995e-13 5295/5170/596/5590/1839/4893/6464/685/857/5290/2309/5747/207/5594/2069/6722/1027/3315/4318/2100/4313/1950/6714/2099/8503/10000/3320/4846/595/2771/208/7514/2353/1956/3845/858/3276/3265/801/8877/3480/5595 42 Poliovirus_type_1 R-HSA-187037 Signaling by NTRK1 (TRKA) 43/1821 80/10654 7.806978903153555e-14 3.686152309950525e-13 1.6255132476201738e-13 5295/9252/4893/6464/5290/3667/5335/4915/5291/5604/5594/5528/673/6774/9261/6714/10818/7867/5519/5598/1432/4914/6195/4803/6654/2885/1398/8660/6196/5518/1213/387/6197/3845/5600/3265/1399/51231/7529/5595/5515/5516/5607 43 Poliovirus_type_1 R-HSA-3371571 HSF1-dependent transactivation 21/1821 24/10654 8.38869957457627e-14 3.9177658520394243e-13 1.727649797967653e-13 818/3303/815/817/84335/3337/3305/64223/1387/3320/2033/816/3326/2475/3306/3304/3312/3297/57521/2288/10728 21 Poliovirus_type_1 R-HSA-5260271 Diseases of Immune System 21/1821 24/10654 8.38869957457627e-14 3.9177658520394243e-13 1.727649797967653e-13 23643/1147/4790/10333/7099/8517/4615/7098/7100/5970/4792/7096/929/114609/695/51135/7187/7097/3551/4791/148022 21 Poliovirus_type_1 R-HSA-5602358 Diseases associated with the TLR signaling cascade 21/1821 24/10654 8.38869957457627e-14 3.9177658520394243e-13 1.727649797967653e-13 23643/1147/4790/10333/7099/8517/4615/7098/7100/5970/4792/7096/929/114609/695/51135/7187/7097/3551/4791/148022 21 Poliovirus_type_1 R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 17/1821 17/10654 8.52249286273238e-14 3.9658820577841295e-13 1.7488680014727288e-13 1147/11035/4790/8737/28512/8517/4615/7098/5970/4792/4793/1660/81030/3551/4791/28511/148022 17 Poliovirus_type_1 R-HSA-442755 Activation of NMDA receptors and postsynaptic events 47/1821 93/10654 1.1564040952378794e-13 5.296193325885132e-13 2.335506427649317e-13 818/5170/5563/815/3838/4893/79861/5567/817/10382/5594/5568/51422/7277/53632/10381/10645/6714/5566/84254/5571/27330/7846/347733/3084/6195/4137/816/2066/5613/1741/1742/5577/1739/6196/5562/10383/1740/6197/3845/3265/5564/801/5565/814/5879/5595 47 Poliovirus_type_1 R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 31/1821 47/10654 1.1586706888282445e-13 5.296193325885132e-13 2.335506427649317e-13 818/815/4893/71/5604/283455/8844/817/5594/409/673/8315/6714/5037/3717/2335/3690/408/1445/816/4296/5894/60/4140/3845/3265/369/801/5245/7529/5595 31 Poliovirus_type_1 R-HSA-6802949 Signaling by RAS mutants 31/1821 47/10654 1.1586706888282445e-13 5.296193325885132e-13 2.335506427649317e-13 818/815/4893/71/5604/283455/8844/817/5594/409/673/8315/6714/5037/3717/2335/3690/408/1445/816/4296/5894/60/4140/3845/3265/369/801/5245/7529/5595 31 Poliovirus_type_1 R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 31/1821 47/10654 1.1586706888282445e-13 5.296193325885132e-13 2.335506427649317e-13 818/815/4893/71/5604/283455/8844/817/5594/409/673/8315/6714/5037/3717/2335/3690/408/1445/816/4296/5894/60/4140/3845/3265/369/801/5245/7529/5595 31 Poliovirus_type_1 R-HSA-9649948 Signaling downstream of RAS mutants 31/1821 47/10654 1.1586706888282445e-13 5.296193325885132e-13 2.335506427649317e-13 818/815/4893/71/5604/283455/8844/817/5594/409/673/8315/6714/5037/3717/2335/3690/408/1445/816/4296/5894/60/4140/3845/3265/369/801/5245/7529/5595 31 Poliovirus_type_1 R-HSA-2500257 Resolution of Sister Chromatid Cohesion 57/1821 126/10654 1.337116657146622e-13 6.090259261703166e-13 2.685672288856894e-13 11130/81929/5903/79861/54908/25936/80776/55869/1783/10382/9212/10274/7277/348995/23421/79023/10381/57122/79980/10735/6232/332/1780/5885/5528/5048/1781/891/5501/8655/983/23279/79902/5519/81565/699/7846/347733/22919/79003/8243/9126/11243/51143/7514/5518/10383/54820/5347/23332/9793/10726/55746/140735/5515/1778/5516 57 Poliovirus_type_1 R-HSA-8943724 Regulation of PTEN gene transcription 36/1821 61/10654 1.827682370756509e-13 8.295361182764578e-13 3.6580744262732206e-13 3725/8841/5468/1822/389541/2146/6045/5594/58528/153129/1108/2122/64223/10014/1958/10325/8649/23512/6009/6615/3066/3065/7157/1107/23028/10542/2475/55004/1386/10670/648/23466/64121/57521/28956/5595 36 Poliovirus_type_1 R-HSA-191859 snRNP Assembly 33/1821 53/10654 2.1634906899530507e-13 9.750837410312874e-13 4.2999078858102597e-13 23165/81929/6635/5903/55706/7175/6606/9631/25929/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/79084/8086/9972/6634/10419/8021/129401/55746/22916/8480 33 Poliovirus_type_1 R-HSA-194441 Metabolism of non-coding RNA 33/1821 53/10654 2.1634906899530507e-13 9.750837410312874e-13 4.2999078858102597e-13 23165/81929/6635/5903/55706/7175/6606/9631/25929/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/79084/8086/9972/6634/10419/8021/129401/55746/22916/8480 33 Poliovirus_type_1 R-HSA-5689896 Ovarian tumor domain proteases 27/1821 38/10654 2.806006942771675e-13 1.2602588673284631e-12 5.557468362724022e-13 56957/7321/8737/10392/8767/57506/7706/8517/7316/79155/983/2099/7415/23586/64127/7128/324/64135/5728/7157/7189/6233/7311/84282/7187/387/7314 27 Poliovirus_type_1 R-HSA-5621575 CD209 (DC-SIGN) signaling 19/1821 21/10654 3.6225127195402485e-13 1.6213260053775628e-12 7.149696156987333e-13 9252/4893/4790/5567/5568/3384/5970/5566/1387/4067/5063/2534/2033/5894/5971/3845/3265/5058/5062 19 Poliovirus_type_1 R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 22/1821 27/10654 3.9768042241720797e-13 1.7737372473902459e-12 7.821796689320428e-13 23643/7186/1612/842/8737/356/355/841/7099/8797/23604/836/929/8837/1613/1630/8772/353376/8717/8743/8795/148022 22 Poliovirus_type_1 R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 21/1821 25/10654 4.396536943737766e-13 1.954184869130338e-12 8.617531577562228e-13 11065/246184/7321/8697/8881/7316/51433/119504/51529/7324/64682/29945/10393/4751/6233/51434/7311/25906/29882/7314/996 21 Poliovirus_type_1 R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 88/1821 244/10654 4.681657338105253e-13 2.0737650545765196e-12 9.144854268680907e-13 10450/7536/23165/23451/7919/81929/6635/5434/5903/6432/8683/6431/55706/7175/9631/7884/27339/5430/9879/6428/27258/8106/9589/3178/23450/348995/79023/57122/23636/3183/10762/5093/23511/10594/4686/6625/53371/11338/1655/9343/3185/3190/56339/23279/4927/9688/79902/2962/22938/988/9883/10236/10250/4670/23020/23225/10189/6434/10482/3181/11193/51729/1660/8086/2521/1977/3191/57721/27316/3187/1665/9972/6634/51593/8021/9775/3192/129401/6427/3312/6426/10291/55746/22916/56259/5725/8480/1994 88 Poliovirus_type_1 R-HSA-193639 p75NTR signals via NF-kB 16/1821 16/10654 5.02284094591398e-13 2.194726094672244e-12 9.678266229414984e-13 4804/4790/5584/8767/8878/4615/7316/5970/4792/4803/3654/7189/6233/7311/3551/7314 16 Poliovirus_type_1 R-HSA-1963640 GRB2 events in ERBB2 signaling 16/1821 16/10654 5.02284094591398e-13 2.194726094672244e-12 9.678266229414984e-13 1839/4893/685/2069/2064/1950/145957/3084/2066/6654/9542/2885/10718/1956/3845/3265 16 Poliovirus_type_1 R-HSA-1963642 PI3K events in ERBB2 signaling 16/1821 16/10654 5.02284094591398e-13 2.194726094672244e-12 9.678266229414984e-13 5295/1839/685/5290/2065/2069/2064/1950/145957/3084/2066/9542/2885/10718/1956/2549 16 Poliovirus_type_1 R-HSA-399954 Sema3A PAK dependent Axon repulsion 16/1821 16/10654 5.02284094591398e-13 2.194726094672244e-12 9.678266229414984e-13 1072/3984/5361/10371/8829/55558/3320/5063/2534/91584/3326/5362/5058/5062/5879/2242 16 Poliovirus_type_1 R-HSA-201681 TCF dependent signaling in response to WNT 85/1821 233/10654 5.711431358912704e-13 2.4871739937967824e-12 1.0967898057655978e-12 5718/5689/8945/5684/857/5720/7015/7090/6597/5682/1499/1459/5700/122706/5707/207/1454/1452/5690/5717/9491/23198/79577/1460/143471/5706/5705/10197/7534/8452/5528/55366/7316/10213/5709/9978/5695/1457/8658/5714/4609/9861/5715/5519/5711/2932/5701/10524/5688/1387/5687/5685/5683/5698/5708/5692/51339/5686/5713/324/2033/5699/5710/5702/3065/7088/5719/208/5704/6233/5716/7514/7311/5518/331/8607/5694/5693/5721/5696/5691/7314/4221/5515/5516 85 Poliovirus_type_1 R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 36/1821 63/10654 7.119815437692064e-13 3.0900478448434584e-12 1.3626441029075722e-12 1147/3665/11035/5434/6737/4790/1499/8737/29110/81844/23220/28512/147945/8517/6778/4615/7098/5591/7316/5970/4792/4793/3428/1387/2033/22954/1660/3661/6233/7311/81030/3551/4791/7314/28511/148022 36 Poliovirus_type_1 R-HSA-69231 Cyclin D associated events in G1 29/1821 44/10654 7.477076863599081e-13 3.223395343538199e-12 1.4214474586669615e-12 8454/25/894/1019/1029/1027/6500/5925/7316/5753/1026/6714/5519/4067/3717/6502/1021/1874/595/5520/6233/1030/7311/5518/1163/1022/7314/5515/5516 29 Poliovirus_type_1 R-HSA-69236 G1 Phase 29/1821 44/10654 7.477076863599081e-13 3.223395343538199e-12 1.4214474586669615e-12 8454/25/894/1019/1029/1027/6500/5925/7316/5753/1026/6714/5519/4067/3717/6502/1021/1874/595/5520/6233/1030/7311/5518/1163/1022/7314/5515/5516 29 Poliovirus_type_1 R-HSA-4570464 SUMOylation of RNA binding proteins 30/1821 47/10654 1.051510669938431e-12 4.517990845168792e-12 1.9923360061991323e-12 23165/81929/5903/55706/7175/9631/6045/348995/79023/57122/23636/3183/10762/23511/53371/3190/23279/4927/9688/79902/9883/23225/8086/7329/9972/8021/648/129401/55746/8480 30 Poliovirus_type_1 R-HSA-1236394 Signaling by ERBB4 34/1821 58/10654 1.1305406534501222e-12 4.841418280057167e-12 2.1349604926143243e-12 5295/1839/4893/6464/685/5290/5241/2065/2069/23118/23385/7316/1950/11059/4734/10413/6714/2099/145957/3084/2066/83737/6285/1742/6654/9542/6233/2885/10718/7311/1956/3845/3265/7314 34 Poliovirus_type_1 R-HSA-109606 Intrinsic Pathway for Apoptosis 32/1821 53/10654 1.6933415371272554e-12 7.227540534294809e-12 3.1871886721809623e-12 23368/596/10018/7531/1029/842/572/7532/207/5594/2810/841/7534/8655/6774/54205/598/836/10000/7157/8626/208/7161/840/331/5599/7159/317/140735/7529/578/5595 32 Poliovirus_type_1 R-HSA-195721 Signaling by WNT 108/1821 331/10654 1.9067598072977086e-12 8.111595351837446e-12 3.5770376791410905e-12 8454/5718/5689/27161/8945/815/5684/857/5720/7015/7090/6885/5579/6597/5682/1499/1459/5700/122706/5707/207/1454/1452/5690/5578/5717/9491/5582/23198/6500/409/79577/1460/143471/5706/3708/5705/10197/192670/7534/8452/5528/55366/7316/10213/5709/9978/5695/1457/8658/5714/4609/9861/5715/5881/5519/5711/2932/5701/10524/5688/1387/5687/5685/5683/5698/5708/5880/5692/51339/5686/5713/324/2033/5699/5710/5702/192669/3065/7088/5719/208/23513/5704/6233/5716/7514/7311/5518/1213/387/331/8607/5593/3845/5694/26523/801/5693/5721/5696/5691/4920/7314/5879/4221/5515/5516 108 Poliovirus_type_1 R-HSA-1433557 Signaling by SCF-KIT 28/1821 43/10654 2.9277350115312004e-12 1.2373280097913826e-11 5.4563482527242394e-12 5295/9402/4893/5290/3815/5578/2241/4318/9306/6774/6772/6714/8651/8503/867/4067/3717/2534/1111/6654/2885/7525/7409/3932/3845/3265/5879/2242 28 Poliovirus_type_1 R-HSA-168325 Viral Messenger RNA Synthesis 28/1821 43/10654 2.9277350115312004e-12 1.2373280097913826e-11 5.4563482527242394e-12 23165/81929/5434/5903/55706/7175/9631/5430/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/2962/9883/23225/8086/9972/8021/129401/55746/8480 28 Poliovirus_type_1 R-HSA-5637810 Constitutive Signaling by EGFRvIII 15/1821 15/10654 2.9589149957684845e-12 1.2423587718389499e-11 5.478532822612659e-12 5295/4893/6464/5290/5335/1950/867/3320/6654/2885/1956/3845/2549/3265/11140 15 Poliovirus_type_1 R-HSA-5637812 Signaling by EGFRvIII in Cancer 15/1821 15/10654 2.9589149957684845e-12 1.2423587718389499e-11 5.478532822612659e-12 5295/4893/6464/5290/5335/1950/867/3320/6654/2885/1956/3845/2549/3265/11140 15 Poliovirus_type_1 R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 39/1821 75/10654 4.505332608929096e-12 1.8855109522433782e-11 8.314694493580698e-12 23165/7919/81929/5903/6432/8683/6431/55706/7175/9631/6428/348995/79023/57122/23636/10762/23511/4686/53371/11338/23279/4927/9688/79902/9883/10250/23225/10189/10482/8086/9972/8021/9775/129401/6427/6426/55746/22916/8480 39 Poliovirus_type_1 R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 25/1821 36/10654 4.9316582649812064e-12 2.0572516192753318e-11 9.072033599352247e-12 26999/25/71/51517/5747/4690/10006/10458/5594/10152/8936/10163/10810/55845/998/695/8976/2885/7454/23191/60/3071/10787/5879/5595 25 Poliovirus_type_1 R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 16/1821 17/10654 7.175230750016606e-12 2.9835072376681956e-11 1.3156620050964237e-11 23643/7186/8737/356/355/841/7099/8797/929/8837/8772/353376/8717/8743/8795/148022 16 Poliovirus_type_1 R-HSA-194315 Signaling by Rho GTPases 135/1821 455/10654 8.510017612252835e-12 3.527142347972316e-11 1.555393301951779e-11 26999/5170/11130/25/81929/5590/5903/1072/3984/79861/54908/71/51517/653361/5579/1499/25936/7531/5747/80776/4690/1783/10006/4627/2316/7532/10928/10458/4771/5578/10382/9212/5594/3985/6722/613/1027/1080/2810/7277/348995/23421/79023/10381/57122/79980/6232/7534/332/1780/5528/6453/5048/1781/5501/8655/5289/5585/4168/10152/6279/6714/23279/23229/79902/50649/5881/5519/8936/1432/81565/10163/699/7846/999/396/10810/347733/5880/22919/55845/5063/9475/995/3895/79003/11243/23221/51143/998/23028/695/10788/1742/6654/90627/8976/2885/5580/7454/7409/23191/7514/6093/57120/367/5518/10383/54820/5347/387/60/5300/5600/23332/5058/801/3071/9793/10726/30849/5586/5062/55746/140735/9886/5500/7529/10787/5879/4221/5595/5515/1778/5516 135 Poliovirus_type_1 R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 29/1821 47/10654 8.723231267879473e-12 3.60392471291559e-11 1.5892526601399852e-11 8454/8841/7090/2648/55869/23462/3280/6500/3091/10013/7316/9978/9759/9612/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/7088/6233/7311/4851/7314 29 Poliovirus_type_1 R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs 55/1821 130/10654 9.87305500684913e-12 4.065932237644897e-11 1.7929879615599565e-11 5718/5689/25/5684/5720/5682/5700/122706/5707/5690/2625/5717/9491/23198/4005/143471/5706/5705/10197/7316/10213/5709/5695/10413/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/83737/5719/5704/6233/5716/7311/7161/5694/1022/5693/5721/5696/5691/7314 55 Poliovirus_type_1 R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 17/1821 19/10654 1.0279744618475973e-11 4.2199333800049453e-11 1.8608991263751343e-11 11065/246184/7321/8697/8881/51433/119504/51529/7324/64682/29945/10393/51434/51343/25906/29882/996 17 Poliovirus_type_1 R-HSA-2871796 FCERI mediated MAPK activation 23/1821 32/10654 1.152347377781956e-11 4.715478634796639e-11 2.0794238396065374e-11 3725/9402/5601/4893/6464/5335/5594/4214/6850/4067/5602/5609/6654/2885/7409/2353/3845/5599/3265/5058/5062/5879/5595 23 Poliovirus_type_1 R-HSA-9006931 Signaling by Nuclear Receptors 98/1821 299/10654 1.5552308506947718e-11 6.343963818182155e-11 2.7975504975855328e-11 5295/5170/27161/3725/3838/596/5434/5590/1839/4893/6464/8841/685/857/5290/1374/7090/5241/2309/5747/7031/8204/5430/207/5451/2625/5594/2069/6722/1027/3315/10274/4318/10735/5481/6720/192670/5885/2100/4313/19/1950/1655/2194/9612/6667/7033/2289/6714/2099/4609/2962/8850/8503/10524/1387/5467/6907/10000/3320/2033/8243/4846/9126/595/192669/3065/2066/23028/6256/2771/208/10498/3326/7514/1025/2353/1386/6908/1956/5914/5536/3169/3845/858/3276/7392/3265/26523/801/8202/8877/3480/2288/10728/2957/10062/5595 98 Poliovirus_type_1 R-HSA-1250347 SHC1 events in ERBB4 signaling 14/1821 14/10654 1.7422720284989848e-11 7.084506765726155e-11 3.1241138814193985e-11 1839/4893/6464/685/2069/145957/3084/2066/6654/9542/2885/10718/3845/3265 14 Poliovirus_type_1 R-HSA-72202 Transport of Mature Transcript to Cytoplasm 41/1821 84/10654 1.818202999497666e-11 7.37001152941035e-11 3.250015292051439e-11 23165/7919/81929/5903/6432/8683/6431/55706/7175/9631/7884/6428/348995/79023/57122/23636/10762/23511/4686/53371/11338/23279/4927/9688/79902/9883/10250/23225/10189/10482/8086/1977/9972/8021/9775/129401/6427/6426/55746/22916/8480 41 Poliovirus_type_1 R-HSA-70326 Glucose metabolism 43/1821 91/10654 2.2933142619389404e-11 9.266714995734463e-11 4.086420397449358e-11 23165/81929/5903/2597/55706/7175/9631/5315/5567/5568/1468/348995/79023/57122/23636/3099/10762/23511/5528/53371/5230/10165/3098/23279/4927/9688/79902/5566/5519/9883/2023/226/23225/4190/8086/9972/5518/8021/129401/55746/8480/5515/5516 43 Poliovirus_type_1 R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 15/1821 16/10654 3.98083785134248e-11 1.598535822548429e-10 7.049196391949301e-11 8454/1147/8945/1326/4790/5604/6500/8517/7316/79155/23291/6233/7311/3551/7314 15 Poliovirus_type_1 R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 15/1821 16/10654 3.98083785134248e-11 1.598535822548429e-10 7.049196391949301e-11 23643/6885/23118/7099/7316/929/3656/10454/7189/6233/7311/353376/7314/148022/257397 15 Poliovirus_type_1 R-HSA-170834 Signaling by TGF-beta Receptor Complex 37/1821 73/10654 4.283679488782324e-11 1.714802130757893e-10 7.561905602950165e-11 5590/7321/10273/4738/7323/54778/7316/5501/9612/6667/4609/4089/22938/23327/867/23645/7046/4088/1874/142/3065/2280/9040/4087/5499/6233/7514/7048/1025/1030/7311/387/7040/23439/5500/7314/4221 37 Poliovirus_type_1 R-HSA-5628897 TP53 Regulates Metabolic Genes 41/1821 86/10654 4.6981656691182855e-11 1.874902646282808e-10 8.26791416432744e-11 27161/5563/7531/389541/7532/207/51422/7249/58528/2810/53632/192670/7534/153129/54205/64223/5571/10325/8649/10000/10128/5728/6009/192669/7157/8626/208/10542/2475/55004/5562/10670/4513/26523/5564/5565/64121/57521/7248/7529/28956 41 Poliovirus_type_1 R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 22/1821 31/10654 4.9081486786810604e-11 1.9526554465493478e-10 8.610787155580808e-11 3725/5601/9252/5594/5528/9261/5519/5598/1432/5602/6195/2353/6196/5518/1386/6197/5599/5600/51231/5595/5515/5516 22 Poliovirus_type_1 R-HSA-912631 Regulation of signaling by CBL 18/1821 22/10654 5.251764764279101e-11 2.0829307018940806e-10 9.185272786107579e-11 5295/5290/5291/7316/3055/6850/8503/867/4067/2534/6233/2885/7525/1398/7409/7311/1399/7314 18 Poliovirus_type_1 R-HSA-186763 Downstream signal transduction 21/1821 29/10654 7.381078843347005e-11 2.9184695181209473e-10 1.286981780887111e-10 5295/4893/5290/5335/5291/4690/5921/6778/6774/6772/6714/5159/6654/2885/1398/8440/9564/3845/3265/1399/5156 21 Poliovirus_type_1 R-HSA-6802957 Oncogenic MAPK signaling 36/1821 71/10654 7.73895379339912e-11 3.050615119171702e-10 1.345255125844367e-10 4000/27044/818/815/4893/71/5604/10018/10142/283455/8844/817/5594/409/10533/673/8315/6714/5037/3717/2335/3690/408/1445/816/4296/5894/60/4140/3845/3265/369/801/5245/7529/5595 36 Poliovirus_type_1 R-HSA-5663220 RHO GTPases Activate Formins 56/1821 140/10654 9.160315006203376e-11 3.5998920862793144e-10 1.587474359226516e-10 11130/81929/5903/79861/54908/71/25936/80776/1783/10382/9212/6722/7277/348995/23421/79023/10381/57122/79980/6232/332/1780/5528/5048/1781/5501/8655/6714/23279/79902/5519/81565/699/7846/347733/22919/79003/11243/51143/998/7514/5518/10383/54820/5347/387/60/23332/9793/10726/55746/140735/5879/5515/1778/5516 56 Poliovirus_type_1 R-HSA-209543 p75NTR recruits signalling complexes 13/1821 13/10654 1.025415744206732e-10 3.9812075128990286e-10 1.7556261949005559e-10 4804/5584/8767/8878/4615/7316/4803/3654/7189/6233/7311/3551/7314 13 Poliovirus_type_1 R-HSA-209560 NF-kB is activated and signals survival 13/1821 13/10654 1.025415744206732e-10 3.9812075128990286e-10 1.7556261949005559e-10 4804/4790/8878/7316/5970/4792/4803/3654/7189/6233/7311/3551/7314 13 Poliovirus_type_1 R-HSA-5357786 TNFR1-induced proapoptotic signaling 13/1821 13/10654 1.025415744206732e-10 3.9812075128990286e-10 1.7556261949005559e-10 7124/7186/56957/8737/7375/841/27005/7128/7132/9099/8772/8717/1540 13 Poliovirus_type_1 R-HSA-8847993 ERBB2 Activates PTK6 Signaling 13/1821 13/10654 1.025415744206732e-10 3.9812075128990286e-10 1.7556261949005559e-10 1839/685/2065/2069/2064/1950/5753/145957/3084/2066/9542/10718/1956 13 Poliovirus_type_1 R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 28/1821 48/10654 1.3326211763223385e-10 5.158404493331815e-10 2.274744539952783e-10 5295/6464/5290/1437/5291/1439/1438/7534/7316/3055/6850/5566/8503/867/3558/4067/3717/2534/6654/6233/2885/7525/1398/3716/7409/7311/1399/7314 28 Poliovirus_type_1 R-HSA-5654741 Signaling by FGFR3 25/1821 40/10654 1.628131554636439e-10 6.264661414705582e-10 2.7625798570421903e-10 5295/4893/6464/5290/5335/5594/7316/673/6714/10818/8569/2261/867/6654/6233/2885/7311/5518/3845/2549/3265/7314/5595/5515/5516 25 Poliovirus_type_1 R-HSA-5675221 Negative regulation of MAPK pathway 25/1821 40/10654 1.628131554636439e-10 6.264661414705582e-10 2.7625798570421903e-10 4893/5604/8844/5594/5528/7316/673/8315/5037/5519/5894/6233/7311/5518/5536/4140/1843/3845/3265/369/7529/7314/5595/5515/5516 25 Poliovirus_type_1 R-HSA-5654738 Signaling by FGFR2 36/1821 73/10654 2.1388808211844902e-10 8.205408864603595e-10 3.618407404259476e-10 5295/5434/4893/6464/5290/23543/5335/5430/5594/3178/4686/7316/673/3185/6714/10818/8569/2962/867/4670/7072/6654/6233/2885/3187/7311/5518/3845/2549/3265/22916/5725/7314/5595/5515/5516 36 Poliovirus_type_1 R-HSA-937039 IRAK1 recruits IKK complex 14/1821 15/10654 2.1991599433408874e-10 8.386737180373976e-10 3.6983692600563045e-10 1147/246330/8517/7316/7335/57162/3654/7189/6233/7311/7334/3551/57161/7314 14 Poliovirus_type_1 R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 14/1821 15/10654 2.1991599433408874e-10 8.386737180373976e-10 3.6983692600563045e-10 1147/246330/8517/7316/7335/57162/3654/7189/6233/7311/7334/3551/57161/7314 14 Poliovirus_type_1 R-HSA-5218921 VEGFR2 mediated cell proliferation 17/1821 21/10654 2.5388670864612425e-10 9.653686355305433e-10 4.2570663769261643e-10 5170/5590/4893/5335/5579/7422/5578/3708/5921/10768/6714/5580/3791/3845/3265/801/8877 17 Poliovirus_type_1 R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 15/1821 17/10654 2.845569867389866e-10 1.0788057526663346e-9 4.757299468701325e-10 23643/6885/23118/7099/7316/929/3656/10454/7189/6233/7311/353376/7314/148022/257397 15 Poliovirus_type_1 R-HSA-193704 p75 NTR receptor-mediated signalling 43/1821 97/10654 3.007249451482937e-10 1.1367579304872451e-9 5.012856008028357e-10 4804/57142/8841/4790/5584/10018/7531/572/8767/4974/835/8878/23421/23385/4615/6453/7316/5970/4792/4168/65078/23229/50649/84894/836/396/4803/11108/3066/3065/3654/7189/6654/4099/6233/7409/7311/26574/387/5599/3551/7314/5879 43 Poliovirus_type_1 R-HSA-5654743 Signaling by FGFR4 25/1821 41/10654 3.496549372173831e-10 1.3178515031380317e-9 5.8114393997349e-10 5295/4893/6464/5290/5335/5594/7316/673/6714/10818/8569/867/2264/6654/6233/2885/7311/5518/3845/2549/3265/7314/5595/5515/5516 25 Poliovirus_type_1 R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 36/1821 75/10654 5.610807604330694e-10 2.1085513125312727e-9 9.298254124101812e-10 5295/1839/685/5290/3667/5291/2065/3815/2069/2064/2260/2100/1950/4233/6714/2099/10818/8503/2261/5159/5880/145957/3084/2534/2264/2066/9542/2885/10718/7409/8660/3932/1956/2549/5156/5879 36 Poliovirus_type_1 R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 12/1821 12/10654 6.032324129269229e-10 2.253816174674793e-9 9.938840670649533e-10 3665/29110/7098/7316/3661/6233/10010/7311/7187/9641/7314/148022 12 Poliovirus_type_1 R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12/1821 12/10654 6.032324129269229e-10 2.253816174674793e-9 9.938840670649533e-10 1147/8737/57506/841/7706/8517/23586/843/64135/84282/8772/3551 12 Poliovirus_type_1 R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 18/1821 24/10654 6.814099432913603e-10 2.53854744769527e-9 1.119444385084681e-9 596/1839/685/2309/5747/207/5594/2069/6722/1027/1950/10000/595/208/7514/2353/1956/5595 18 Poliovirus_type_1 R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 46/1821 110/10654 7.771153596086373e-10 2.8867484107652264e-9 1.2729934603023333e-9 1017/3725/1019/11065/4790/246184/1029/7321/8697/5594/1027/1051/79813/3576/3490/8881/7316/6774/5970/1026/51433/5598/3552/1021/119504/6195/51529/7324/64682/29945/10393/6233/51434/2353/1030/51343/7311/6196/25906/6197/29882/3569/10919/7314/996/5595 46 Poliovirus_type_1 R-HSA-141424 Amplification of signal from the kinetochores 42/1821 96/10654 7.972033921530654e-10 2.9443987750295166e-9 1.2984160210003178e-9 11130/81929/5903/54908/25936/80776/1783/9212/348995/23421/79023/57122/79980/6232/332/1780/5528/5048/1781/5501/8655/23279/79902/5519/81565/699/22919/79003/11243/51143/7514/5518/54820/5347/23332/9793/10726/55746/140735/5515/1778/5516 42 Poliovirus_type_1 R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 42/1821 96/10654 7.972033921530654e-10 2.9443987750295166e-9 1.2984160210003178e-9 11130/81929/5903/54908/25936/80776/1783/9212/348995/23421/79023/57122/79980/6232/332/1780/5528/5048/1781/5501/8655/23279/79902/5519/81565/699/22919/79003/11243/51143/7514/5518/54820/5347/23332/9793/10726/55746/140735/5515/1778/5516 42 Poliovirus_type_1 R-HSA-5218920 VEGFR2 mediated vascular permeability 20/1821 29/10654 8.559320640161652e-10 3.152275515762391e-9 1.390085156597682e-9 5170/857/1499/207/57761/64223/10000/3320/5063/4846/3728/208/79109/2475/7409/5058/801/5062/5879/253260 20 Poliovirus_type_1 R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 28/1821 51/10654 9.210902961597777e-10 3.382579463675081e-9 1.4916442043073322e-9 5321/79861/11258/1783/10382/93661/55860/830/7277/10381/10671/1780/5048/1781/8655/84516/1639/832/10121/7846/347733/51143/10540/10383/140735/829/51164/1778 28 Poliovirus_type_1 R-HSA-198323 AKT phosphorylates targets in the cytosol 13/1821 14/10654 1.2090866781845562e-9 4.383948767069611e-9 1.9332263559818633e-9 1147/842/572/207/84335/1027/7249/1026/2932/10000/208/2931/4193 13 Poliovirus_type_1 R-HSA-3371568 Attenuation phase 13/1821 14/10654 1.2090866781845562e-9 4.383948767069611e-9 1.9332263559818633e-9 3303/3337/3305/1387/3320/2033/3326/3306/3304/3312/3297/2288/10728 13 Poliovirus_type_1 R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 13/1821 14/10654 1.2090866781845562e-9 4.383948767069611e-9 1.9332263559818633e-9 4893/5921/1793/5753/1398/9844/387/9564/3845/3265/63916/5829/5879 13 Poliovirus_type_1 R-HSA-918233 TRAF3-dependent IRF activation pathway 13/1821 14/10654 1.2090866781845562e-9 4.383948767069611e-9 1.9332263559818633e-9 3665/29110/57506/7706/23586/1387/2033/64135/3661/84282/7187/9641/3456 13 Poliovirus_type_1 R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 16/1821 20/10654 1.2141735530208312e-9 4.383948767069611e-9 1.9332263559818633e-9 11065/246184/7321/8697/8881/51433/119504/51529/7324/64682/29945/10393/51434/25906/29882/996 16 Poliovirus_type_1 R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 16/1821 20/10654 1.2141735530208312e-9 4.383948767069611e-9 1.9332263559818633e-9 11065/246184/7321/8697/8881/51433/119504/51529/7324/64682/29945/10393/51434/25906/29882/996 16 Poliovirus_type_1 R-HSA-6802952 Signaling by BRAF and RAF fusions 33/1821 67/10654 1.2611378177077444e-9 4.5408006900147555e-9 2.0023946532260573e-9 4000/27044/818/815/4893/71/5604/10018/10142/283455/8844/817/5594/409/10533/673/6714/5037/3717/2335/3690/408/1445/816/5894/60/4140/3845/3265/369/801/7529/5595 33 Poliovirus_type_1 R-HSA-5674135 MAP2K and MAPK activation 24/1821 40/10654 1.2663961668905853e-9 4.547032476662853e-9 2.0051427360237976e-9 4893/71/5604/283455/8844/5594/409/673/6714/5037/8649/2335/3690/408/1445/5894/60/4140/3845/3265/369/7529/28956/5595 24 Poliovirus_type_1 R-HSA-2173789 TGF-beta receptor signaling activates SMADs 21/1821 32/10654 1.30992902217397e-9 4.690273637728465e-9 2.068308982379953e-9 10273/4738/7316/5501/4089/23327/867/23645/7046/4088/2280/9040/4087/5499/6233/7514/7048/7311/7040/5500/7314 21 Poliovirus_type_1 R-HSA-190236 Signaling by FGFR 39/1821 87/10654 1.3507208019071655e-9 4.822933832848577e-9 2.126809252164658e-9 5295/5434/4893/6464/5290/23543/5335/5430/5594/3178/2260/4686/7316/673/3185/6714/10818/8569/2962/2261/867/4670/2264/7072/6654/6233/2885/3187/7311/5518/3845/2549/3265/22916/5725/7314/5595/5515/5516 39 Poliovirus_type_1 R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 15/1821 18/10654 1.4359898565042271e-9 5.113234599541295e-9 2.2548255961392346e-9 23643/3665/29110/7099/7316/929/3661/6233/10010/7311/7187/9641/353376/7314/148022 15 Poliovirus_type_1 R-HSA-1295596 Spry regulation of FGF signaling 14/1821 16/10654 1.4806693050787372e-9 5.257803675610171e-9 2.318577424220728e-9 5594/7316/673/6714/8569/867/6233/2885/7311/5518/7314/5595/5515/5516 14 Poliovirus_type_1 R-HSA-4551638 SUMOylation of chromatin organization proteins 34/1821 71/10654 1.8252119510224173e-9 6.4634566067799335e-9 2.850244226582144e-9 23165/81929/5903/55706/7175/9631/6045/348995/79023/57122/23636/10762/23511/53371/9759/23279/4927/9688/79902/9883/23225/23512/3066/3065/1107/8086/7329/9972/6612/8021/648/129401/55746/8480 34 Poliovirus_type_1 R-HSA-9006115 Signaling by NTRK2 (TRKB) 18/1821 25/10654 2.0438733364331892e-9 7.198231504542024e-9 3.1742640255217783e-9 5295/4893/6464/5290/5335/4915/1795/6714/10818/2534/6654/2885/8851/3845/2549/3265/1020/5879 18 Poliovirus_type_1 R-HSA-9006335 Signaling by Erythropoietin 18/1821 25/10654 2.0438733364331892e-9 7.198231504542024e-9 3.1742640255217783e-9 5295/4893/6464/5290/5335/5291/4067/23533/3717/5294/6654/2885/7409/8660/3845/2549/3265/1399 18 Poliovirus_type_1 R-HSA-9006936 Signaling by TGF-beta family members 43/1821 102/10654 2.050605110245373e-9 7.202261545248735e-9 3.1760411860963757e-9 5590/7321/10273/4738/269/130399/7323/54778/7316/5501/91/93/9612/6667/4609/4089/22938/23327/867/23645/7046/4088/1874/142/94/3065/2280/9040/4087/5499/657/6233/7514/7048/1025/1030/7311/387/7040/23439/5500/7314/4221 43 Poliovirus_type_1 R-HSA-429914 Deadenylation-dependent mRNA decay 29/1821 56/10654 2.859156542812896e-9 1.0014817346972345e-8 4.416317314413513e-9 1656/9924/80153/5073/27257/27258/4849/4850/255967/26986/10605/9337/25904/246175/4848/23019/1981/1973/1977/1975/55571/9775/54464/57472/85456/29883/1974/167227/80349 29 Poliovirus_type_1 R-HSA-3371378 Regulation by c-FLIP 11/1821 11/10654 3.5470732435255486e-9 1.2257848286607057e-8 5.405445326665151e-9 7186/8737/356/355/841/8797/8837/8772/8717/8743/8795 11 Poliovirus_type_1 R-HSA-5218900 CASP8 activity is inhibited 11/1821 11/10654 3.5470732435255486e-9 1.2257848286607057e-8 5.405445326665151e-9 7186/8737/356/355/841/8797/8837/8772/8717/8743/8795 11 Poliovirus_type_1 R-HSA-5655291 Signaling by FGFR4 in disease 11/1821 11/10654 3.5470732435255486e-9 1.2257848286607057e-8 5.405445326665151e-9 5295/4893/5290/5335/10818/2264/6654/2885/3845/2549/3265 11 Poliovirus_type_1 R-HSA-69416 Dimerization of procaspase-8 11/1821 11/10654 3.5470732435255486e-9 1.2257848286607057e-8 5.405445326665151e-9 7186/8737/356/355/841/8797/8837/8772/8717/8743/8795 11 Poliovirus_type_1 R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 11/1821 11/10654 3.5470732435255486e-9 1.2257848286607057e-8 5.405445326665151e-9 6885/23118/7098/7316/10454/7189/6233/7311/7314/148022/257397 11 Poliovirus_type_1 R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 22/1821 36/10654 3.835386053711306e-9 1.3218750329502335e-8 5.8291822938477506e-9 4893/71/5604/283455/8844/5594/409/673/6714/5037/2335/3690/408/1445/5894/60/4140/3845/3265/369/7529/5595 22 Poliovirus_type_1 R-HSA-1980143 Signaling by NOTCH1 34/1821 73/10654 4.537010375138473e-9 1.5595216996142643e-8 6.87715256863095e-9 8454/8841/7090/2648/55869/23462/3280/23220/6500/409/3091/10013/23385/7316/9978/9759/9612/4609/10014/22938/8850/1387/6907/2033/408/55294/3066/3065/7088/83737/6233/7311/4851/7314 34 Poliovirus_type_1 R-HSA-447115 Interleukin-12 family signaling 29/1821 57/10654 4.87573365326279e-9 1.671494861450994e-8 7.37092993494375e-9 1072/9049/3593/6775/821/9987/3313/6175/3185/6774/6772/6647/149233/6950/3717/3458/3181/998/6648/4001/3716/3594/51561/4282/7297/5062/5721/5034/829 29 Poliovirus_type_1 R-HSA-400253 Circadian Clock 33/1821 70/10654 5.214826820572784e-9 1.7830004699518086e-8 7.862645492417434e-9 8454/26224/8945/8841/1374/8204/1454/4862/1407/6500/3091/1408/6720/5465/406/7316/5501/1387/2908/6907/2033/6256/5499/10498/6233/7311/23054/1386/23411/1453/5500/10891/7314 33 Poliovirus_type_1 R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 12/1821 13/10654 6.611522475001918e-9 2.254564145576051e-8 9.942139060153261e-9 2065/207/10193/2064/7316/10000/3084/208/9542/6233/7311/7314 12 Poliovirus_type_1 R-HSA-187687 Signalling to ERKs 21/1821 34/10654 6.632748144250705e-9 2.2558343952346065e-8 9.94774058573915e-9 4893/6464/5604/5594/673/9261/6714/10818/7867/1432/4914/4803/6654/2885/1398/3845/5600/3265/1399/7529/5595 21 Poliovirus_type_1 R-HSA-162599 Late Phase of HIV Life Cycle 52/1821 139/10654 6.867303371242628e-9 2.3294615909294075e-8 1.0272420555321385e-8 23165/6875/81929/5434/5903/55706/7175/9631/2959/5430/27243/6878/348995/79023/57122/23636/10762/23511/4686/7316/6872/2960/53371/51534/23279/4927/9688/8731/79902/2962/23327/9883/23225/5901/8086/6233/7514/1025/7311/9972/6880/6908/8021/129401/6829/6882/1022/55746/22916/8480/2957/7314 52 Poliovirus_type_1 R-HSA-6785631 ERBB2 Regulates Cell Motility 13/1821 15/10654 7.638696123212634e-9 2.5843252763309934e-8 1.139631414984065e-8 1839/685/2065/2069/2064/1950/145957/3084/2066/9542/10718/387/1956 13 Poliovirus_type_1 R-HSA-877300 Interferon gamma signaling 39/1821 92/10654 9.501301981199785e-9 3.2060676056980423e-8 1.4138063019696567e-8 3665/818/815/6737/10379/23321/4281/7412/817/9021/9830/3123/23650/3383/7706/3126/2634/51127/3662/3115/3122/3394/3663/3664/6772/8651/3659/3717/3458/816/3661/10346/5371/5580/3716/10107/3127/3125/3660 39 Poliovirus_type_1 R-HSA-177929 Signaling by EGFR 26/1821 49/10654 9.670736940619311e-9 3.2462447699110134e-8 1.4315235602890429e-8 5295/1839/4893/6464/685/5290/5335/2069/7316/1950/6714/867/6455/1445/998/6654/30011/6233/2885/7311/1956/3845/2549/3265/5829/7314 26 Poliovirus_type_1 R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 26/1821 49/10654 9.670736940619311e-9 3.2462447699110134e-8 1.4315235602890429e-8 1017/4849/1027/4869/4850/2810/9337/891/983/1026/6790/25904/246175/4848/23019/2033/995/1874/7157/10498/55571/55835/57472/3276/85456/29883 26 Poliovirus_type_1 R-HSA-162587 HIV Life Cycle 55/1821 152/10654 1.0112232645937065e-8 3.3856280209384095e-8 1.492988551963367e-8 23165/6875/81929/5434/5903/55706/7175/9631/3159/2959/5430/27243/6878/348995/79023/57122/23636/10762/23511/4686/7316/6872/2960/53371/920/51534/23279/4927/9688/8731/79902/2962/23327/9883/23225/5901/8086/3836/6233/7514/1025/7311/9972/6880/6908/8021/129401/6829/6882/1022/55746/22916/8480/2957/7314 55 Poliovirus_type_1 R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 33/1821 72/10654 1.2611940063056252e-8 4.211603818984329e-8 1.85722597056187e-8 6517/8773/5563/79861/71/7531/4627/7532/207/10382/51422/2810/7277/53632/10381/7534/8766/60412/149371/4641/5571/7846/347733/208/10383/60/5564/801/5565/4218/7529/5879/55770 33 Poliovirus_type_1 R-HSA-389357 CD28 dependent PI3K/Akt signaling 16/1821 22/10654 1.3216557958919714e-8 4.40210418838437e-8 1.941232503146103e-8 5295/5170/1326/5290/207/57761/9020/64223/8503/10000/2534/208/79109/2475/3932/253260 16 Poliovirus_type_1 R-HSA-114452 Activation of BH3-only proteins 19/1821 30/10654 1.95022795389062e-8 6.462323477030873e-8 2.849744540930686e-8 23368/596/10018/7531/572/7532/207/2810/7534/8655/10000/7157/8626/208/7161/5599/7159/140735/7529 19 Poliovirus_type_1 R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 19/1821 30/10654 1.95022795389062e-8 6.462323477030873e-8 2.849744540930686e-8 818/5170/815/4893/817/5594/27330/6195/816/1741/1742/1739/6196/1740/6197/3845/3265/801/5595 19 Poliovirus_type_1 R-HSA-1250342 PI3K events in ERBB4 signaling 10/1821 10/10654 2.0847624298225228e-8 6.820453736145259e-8 3.007672220422555e-8 5295/1839/685/5290/2069/145957/3084/2066/9542/10718 10 Poliovirus_type_1 R-HSA-193697 p75NTR regulates axonogenesis 10/1821 10/10654 2.0847624298225228e-8 6.820453736145259e-8 3.007672220422555e-8 4804/57142/4974/4168/65078/84894/396/4803/4099/387 10 Poliovirus_type_1 R-HSA-450341 Activation of the AP-1 family of transcription factors 10/1821 10/10654 2.0847624298225228e-8 6.820453736145259e-8 3.007672220422555e-8 3725/5601/5594/1432/5602/2353/1386/5599/5600/5595 10 Poliovirus_type_1 R-HSA-8853334 Signaling by FGFR3 fusions in cancer 10/1821 10/10654 2.0847624298225228e-8 6.820453736145259e-8 3.007672220422555e-8 5295/4893/5290/10818/2261/6654/2885/3845/2549/3265 10 Poliovirus_type_1 R-HSA-937042 IRAK2 mediated activation of TAK1 complex 10/1821 10/10654 2.0847624298225228e-8 6.820453736145259e-8 3.007672220422555e-8 6885/23118/7316/3656/10454/7189/6233/7311/7314/257397 10 Poliovirus_type_1 R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 14/1821 18/10654 2.675540606022435e-8 8.731067952311187e-8 3.85021166489571e-8 1839/4893/5578/5594/5598/6195/6654/2885/6196/1956/6197/3845/3265/5595 14 Poliovirus_type_1 R-HSA-3371511 HSF1 activation 11/1821 12/10654 3.592932238011032e-8 1.1695175895950051e-7 5.1573190019297114e-8 6118/7531/1915/10013/7415/6119/3320/3326/6117/3297/10728 11 Poliovirus_type_1 R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 15/1821 21/10654 5.686019075511251e-8 1.8461658912680108e-7 8.141191305252753e-8 4849/4869/4850/9337/25904/246175/4848/23019/995/7157/55571/55835/57472/85456/29883 15 Poliovirus_type_1 R-HSA-5654736 Signaling by FGFR1 25/1821 50/10654 8.767888447203815e-8 2.8396503036295774e-7 1.2522242162100136e-7 5295/4893/6464/5290/5335/5594/2260/7316/673/6714/10818/8569/867/6654/6233/2885/7311/5518/3845/2549/3265/7314/5595/5515/5516 25 Poliovirus_type_1 R-HSA-9020591 Interleukin-12 signaling 24/1821 47/10654 9.470043404631912e-8 3.0593699119224396e-7 1.3491157996309808e-7 1072/9049/3593/6775/9987/3313/6175/3185/6647/6950/3717/3458/3181/998/6648/4001/3716/3594/4282/7297/5062/5721/5034/829 24 Poliovirus_type_1 R-HSA-5696394 DNA Damage Recognition in GG-NER 21/1821 38/10654 1.0205100881814063e-7 3.288593759164582e-7 1.450198546363051e-7 10445/8450/7316/9978/10980/4798/1642/142/10987/1069/6233/2873/7311/60/8533/8607/5886/50813/7314/51138/8451 21 Poliovirus_type_1 R-HSA-6784531 tRNA processing in the nucleus 27/1821 57/10654 1.1349295204296086e-7 3.648189904822358e-7 1.608772650038033e-7 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/1653/9972/8021/129401/55746/8480 27 Poliovirus_type_1 R-HSA-74751 Insulin receptor signalling cascade 26/1821 54/10654 1.2881779848259857e-7 4.1305010508475017e-7 1.8214614082378435e-7 5295/5170/3643/4893/6464/5290/3667/5291/5594/2322/57761/2260/5289/10818/2261/2264/3630/208/6654/2885/8660/3845/2549/3265/30849/5595 26 Poliovirus_type_1 R-HSA-198753 ERK/MAPK targets 15/1821 22/10654 1.5038226103266828e-7 4.809993411193783e-7 2.1211028067817915e-7 9252/5594/5528/5519/5598/1432/6195/6196/5518/6197/5600/51231/5595/5515/5516 15 Poliovirus_type_1 R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 12/1821 15/10654 1.6457590178668038e-7 5.237983639581013e-7 2.3098372180586722e-7 6737/29110/81844/23220/147945/7316/22954/3661/6233/7311/81030/7314 12 Poliovirus_type_1 R-HSA-844456 The NLRP3 inflammasome 12/1821 15/10654 1.6457590178668038e-7 5.237983639581013e-7 2.3098372180586722e-7 834/351/4790/10910/9051/29108/5970/10628/3326/4210/114548/4791 12 Poliovirus_type_1 R-HSA-9022692 Regulation of MECP2 expression and activity 19/1821 33/10654 1.7318648292149493e-7 5.498457548911502e-7 2.424700564625545e-7 818/27161/815/8841/817/9212/192670/9612/5566/6907/3064/816/192669/3066/3065/25942/26523/801/814 19 Poliovirus_type_1 R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 27/1821 58/10654 1.779967032182061e-7 5.582427018206026e-7 2.461729280005924e-7 8454/8841/2648/55869/23462/3280/6500/10013/23385/7316/9978/9759/9612/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/6233/7311/4851/7314 27 Poliovirus_type_1 R-HSA-2644603 Signaling by NOTCH1 in Cancer 27/1821 58/10654 1.779967032182061e-7 5.582427018206026e-7 2.461729280005924e-7 8454/8841/2648/55869/23462/3280/6500/10013/23385/7316/9978/9759/9612/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/6233/7311/4851/7314 27 Poliovirus_type_1 R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 27/1821 58/10654 1.779967032182061e-7 5.582427018206026e-7 2.461729280005924e-7 8454/8841/2648/55869/23462/3280/6500/10013/23385/7316/9978/9759/9612/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/6233/7311/4851/7314 27 Poliovirus_type_1 R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 27/1821 58/10654 1.779967032182061e-7 5.582427018206026e-7 2.461729280005924e-7 8454/8841/2648/55869/23462/3280/6500/10013/23385/7316/9978/9759/9612/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/6233/7311/4851/7314 27 Poliovirus_type_1 R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 27/1821 58/10654 1.779967032182061e-7 5.582427018206026e-7 2.461729280005924e-7 8454/8841/2648/55869/23462/3280/6500/10013/23385/7316/9978/9759/9612/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/6233/7311/4851/7314 27 Poliovirus_type_1 R-HSA-3928662 EPHB-mediated forward signaling 22/1821 42/10654 1.8107605974148041e-7 5.665219441911851e-7 2.498238943801723e-7 1072/3984/71/5747/3985/5921/6453/2051/6714/4067/2047/2534/9475/998/8976/7525/6093/387/60/3265/5058/5879 22 Poliovirus_type_1 R-HSA-5603041 IRAK4 deficiency (TLR2/4) 10/1821 11/10654 1.9385313484522227e-7 6.021125079891362e-7 2.6551856136060885e-7 23643/10333/7099/4615/7096/929/114609/695/51135/7097 10 Poliovirus_type_1 R-HSA-9614399 Regulation of localization of FOXO transcription factors 10/1821 11/10654 1.9385313484522227e-7 6.021125079891362e-7 2.6551856136060885e-7 2308/2309/7532/207/4303/2810/7534/10000/208/7529 10 Poliovirus_type_1 R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 10/1821 11/10654 1.9385313484522227e-7 6.021125079891362e-7 2.6551856136060885e-7 6885/23118/7316/80216/10454/7189/6233/7311/7314/257397 10 Poliovirus_type_1 R-HSA-879415 Advanced glycosylation endproduct receptor signaling 11/1821 13/10654 1.9717722185820724e-7 6.109649975366085e-7 2.6942231731637636e-7 351/6283/1650/5594/830/177/3146/6288/6285/829/5595 11 Poliovirus_type_1 R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 16/1821 25/10654 2.1524840682899182e-7 6.637684124463408e-7 2.9270747843781316e-7 9252/5594/5528/9261/5519/5598/1432/6195/6196/5518/6197/5600/51231/5595/5515/5516 16 Poliovirus_type_1 R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 16/1821 25/10654 2.1524840682899182e-7 6.637684124463408e-7 2.9270747843781316e-7 1017/2305/51400/891/993/983/5519/995/5520/7514/5518/5347/7465/1022/5515/5516 16 Poliovirus_type_1 R-HSA-622312 Inflammasomes 14/1821 20/10654 2.402987027014805e-7 7.392482763298529e-7 3.2599246189875516e-7 834/596/351/4790/10910/9051/29108/5970/598/10628/3326/4210/114548/4791 14 Poliovirus_type_1 R-HSA-2173788 Downregulation of TGF-beta receptor signaling 16/1821 26/10654 4.707768498869166e-7 1.4448365702481798e-6 6.371416013507142e-7 10273/7316/5501/23327/23645/7046/4088/4087/5499/6233/7514/7048/7311/7040/5500/7314 16 Poliovirus_type_1 R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 22/1821 44/10654 5.223304210032208e-7 1.5992491987485787e-6 7.052342226321772e-7 7321/7323/54778/7316/9612/6667/4609/4089/22938/23327/4088/1874/142/3065/4087/6233/1025/1030/7311/23439/7314/4221 22 Poliovirus_type_1 R-HSA-5205647 Mitophagy 17/1821 29/10654 5.481765732324751e-7 1.6665084973977839e-6 7.348941150584326e-7 65018/1459/9140/8878/10452/1460/9474/7316/1457/6714/8408/81631/6233/9804/7311/84557/7314 17 Poliovirus_type_1 R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 17/1821 29/10654 5.481765732324751e-7 1.6665084973977839e-6 7.348941150584326e-7 2308/2309/4303/4287/6720/847/4089/4088/2908/3630/3066/3065/6648/4087/91584/25942/10891 17 Poliovirus_type_1 R-HSA-9619483 Activation of AMPK downstream of NMDARs 17/1821 29/10654 5.481765732324751e-7 1.6665084973977839e-6 7.348941150584326e-7 5563/79861/10382/51422/7277/53632/10381/10645/5571/7846/347733/4137/5562/10383/5564/801/5565 17 Poliovirus_type_1 R-HSA-1433559 Regulation of KIT signaling 12/1821 16/10654 5.55333170141344e-7 1.6803390993243955e-6 7.409931106407854e-7 3815/5578/9306/6714/8651/867/4067/2534/6654/2885/7525/3932 12 Poliovirus_type_1 R-HSA-399956 CRMPs in Sema3A signaling 12/1821 16/10654 5.55333170141344e-7 1.6803390993243955e-6 7.409931106407854e-7 1400/5361/10371/8829/2932/55558/2534/91584/5362/8851/1020/2242 12 Poliovirus_type_1 R-HSA-211000 Gene Silencing by RNA 47/1821 136/10654 5.653447121385673e-7 1.7066260748164244e-6 7.52585096893446e-7 11022/23165/27161/81929/5434/8468/5903/55706/7175/9631/5430/91646/122402/348995/79023/57122/23636/192670/10762/23511/56165/53371/55124/23279/4927/9688/79902/9883/23225/84944/3320/54514/192669/5901/8086/29102/9972/54456/8021/129401/26523/143689/9271/55746/23405/136991/8480 47 Poliovirus_type_1 R-HSA-111465 Apoptotic cleavage of cellular proteins 20/1821 38/10654 5.945510790498058e-7 1.790598927325233e-6 7.896153041979715e-7 4000/51765/1499/5747/841/7082/660/10134/329/999/5588/836/324/4137/4001/5580/6709/6093/839/840 20 Poliovirus_type_1 R-HSA-1221632 Meiotic synapsis 32/1821 79/10654 6.939089606224064e-7 2.084961888676648e-6 9.194229879428279e-7 4000/7014/10388/25913/8468/25777/23224/27127/93426/10274/7013/545/10735/56158/5885/644186/26277/9985/23345/256126/10734/65057/8243/9126/7329/4001/50511/6847/672/3306/23353/54386 32 Poliovirus_type_1 R-HSA-180336 SHC1 events in EGFR signaling 11/1821 14/10654 7.770645320666453e-7 2.323981860403494e-6 1.0248256131786263e-6 1839/4893/6464/685/2069/1950/6654/2885/1956/3845/3265 11 Poliovirus_type_1 R-HSA-9027284 Erythropoietin activates RAS 11/1821 14/10654 7.770645320666453e-7 2.323981860403494e-6 1.0248256131786263e-6 4893/6464/4067/3717/6654/2885/7409/8660/3845/3265/1399 11 Poliovirus_type_1 R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 15/1821 24/10654 8.168014126457493e-7 2.4371690298619695e-006 1.0747387008496704e-6 5590/653361/5579/5578/5594/5289/6279/1432/5880/5580/5300/5600/30849/5879/5595 15 Poliovirus_type_1 R-HSA-1489509 DAG and IP3 signaling 21/1821 42/10654 9.480428264448118e-7 2.822233725836865e-6 1.244543883019809e-6 818/815/3838/5335/5567/817/5578/5568/5582/3708/10768/10645/5566/84254/816/5613/5577/5580/5581/801/814 21 Poliovirus_type_1 R-HSA-6804760 Regulation of TP53 Activity through Methylation 13/1821 19/10654 9.95541841654112e-7 2.956805147216936e-6 1.3038869621470302e-6 472/79813/7316/4194/56950/2033/7157/6233/7311/10419/10919/7314/4193 13 Poliovirus_type_1 R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 9/1821 10/10654 1.0371117822795935e-6 3.0521394688547854e-6 1.3459273310045194e-6 5563/51422/53632/1432/5571/5600/5564/5565/10891 9 Poliovirus_type_1 R-HSA-2562578 TRIF-mediated programmed cell death 9/1821 10/10654 1.0371117822795935e-6 3.0521394688547854e-6 1.3459273310045194e-6 23643/11035/8737/841/7099/929/8772/353376/148022 9 Poliovirus_type_1 R-HSA-5602498 MyD88 deficiency (TLR2/4) 9/1821 10/10654 1.0371117822795935e-6 3.0521394688547854e-6 1.3459273310045194e-6 23643/10333/7099/4615/7096/929/114609/695/7097 9 Poliovirus_type_1 R-HSA-74749 Signal attenuation 9/1821 10/10654 1.0371117822795935e-6 3.0521394688547854e-6 1.3459273310045194e-6 3643/6464/3667/5594/3630/6654/2885/8660/5595 9 Poliovirus_type_1 R-HSA-75153 Apoptotic execution phase 24/1821 52/10654 1.0402310753350671e-6 3.054345913683147e-6 1.346900325334939e-6 4000/3837/51765/1499/5747/841/7082/660/3146/10134/329/999/5588/836/324/4137/4001/3836/5580/6709/6093/839/840/5062 24 Poliovirus_type_1 R-HSA-2559585 Oncogene Induced Senescence 18/1821 33/10654 1.0955488480621446e-6 3.2094601480729645e-6 1.4153023396018137e-6 1019/1029/5594/5925/192670/7316/6667/4194/1021/192669/7157/6233/1030/7311/26523/7314/5595/4193 18 Poliovirus_type_1 R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 14/1821 22/10654 1.4065642913269094e-6 4.1019488043447645e-6 1.8088704865837847e-6 4000/3725/351/2309/10018/7531/356/823/993/995/6648/4001/8851/1020 14 Poliovirus_type_1 R-HSA-8863678 Neurodegenerative Diseases 14/1821 22/10654 1.4065642913269094e-6 4.1019488043447645e-6 1.8088704865837847e-6 4000/3725/351/2309/10018/7531/356/823/993/995/6648/4001/8851/1020 14 Poliovirus_type_1 R-HSA-180292 GAB1 signalosome 12/1821 17/10654 1.5931210016294654e-6 4.6204197617041544e-6 2.0375049375854344e-6 5295/1839/685/5290/2069/1950/6714/1445/2885/1956/2549/5829 12 Poliovirus_type_1 R-HSA-9034015 Signaling by NTRK3 (TRKC) 12/1821 17/10654 1.5931210016294654e-6 4.6204197617041544e-6 2.0375049375854344e-6 5295/4893/6464/5290/3667/5335/6714/6654/2885/3845/3265/4916 12 Poliovirus_type_1 R-HSA-2428924 IGF1R signaling cascade 24/1821 53/10654 1.595102245118967e-6 4.6204197617041544e-6 2.0375049375854344e-6 5295/5170/4893/6464/5290/3667/5291/2322/57761/2260/5289/10818/2261/8471/2264/208/6654/2885/8660/3845/2549/3265/30849/3480 24 Poliovirus_type_1 R-HSA-167044 Signalling to RAS 13/1821 20/10654 2.398136242566152e-6 6.930936360241637e-6 3.056392662227336e-6 4893/6464/9261/6714/7867/1432/4914/4803/6654/2885/3845/5600/3265 13 Poliovirus_type_1 R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 24/1821 54/10654 2.409206405969264e-6 6.947353595736871e-6 3.063632307131526e-6 5295/5170/4893/6464/5290/3667/5291/2322/57761/2260/5289/10818/2261/8471/2264/208/6654/2885/8660/3845/2549/3265/30849/3480 24 Poliovirus_type_1 R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 11/1821 15/10654 2.4614082653365453e-6 7.082042977720551e-6 3.123027404327384e-6 3665/4615/7316/7335/3654/7189/6233/51135/7311/7334/7314 11 Poliovirus_type_1 R-HSA-373755 Semaphorin interactions 27/1821 65/10654 2.8602738706935513e-6 8.211343027447633e-6 3.621024241412537e-6 1400/1072/3984/5361/4627/3985/10371/2064/8829/4233/2932/55558/3320/5063/2534/9475/91584/3326/6093/5362/387/8851/5058/1020/5062/5879/2242 27 Poliovirus_type_1 R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 14/1821 23/10654 3.0285157360520076e-6 8.675015075046752e-6 3.825493561328852e-6 7321/7323/54778/7316/9612/4089/23327/4088/142/3065/4087/6233/7311/7314 14 Poliovirus_type_1 R-HSA-111996 Ca-dependent events 19/1821 38/10654 3.130556756421221e-6 8.947422747288145e-6 3.945619438598342e-6 818/815/3838/5321/5567/817/5578/5594/5568/5582/10645/5566/84254/816/5613/5577/5580/801/814 19 Poliovirus_type_1 R-HSA-114604 GPVI-mediated activation cascade 18/1821 35/10654 3.38754670091266e-6 9.660503755478803e-6 4.260072702591608e-6 5295/5170/5590/5290/5291/6850/8503/146850/4067/23533/5880/5294/2534/998/7409/3932/387/5879 18 Poliovirus_type_1 R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 32/1821 84/10654 3.4042265136177186e-6 9.686640123737835e-6 4.271598274319898e-6 6118/10445/7515/8450/54778/7316/9978/10980/6119/4798/10401/1642/142/10987/1069/7329/6233/2873/7311/6612/60/8533/8607/6117/7334/5981/1022/5886/50813/7314/51138/8451 32 Poliovirus_type_1 R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 17/1821 32/10654 3.554748002207559e-6 1.0092665583360229e-5 4.45064669879917e-6 54778/7316/6667/4609/4089/22938/4088/1874/3065/4087/6233/1025/1030/7311/23439/7314/4221 17 Poliovirus_type_1 R-HSA-5654732 Negative regulation of FGFR3 signaling 16/1821 29/10654 3.583215326968358e-6 1.0151130893323546e-5 4.476428632881234e-6 5594/7316/673/6714/10818/8569/2261/867/6233/2885/7311/5518/7314/5595/5515/5516 16 Poliovirus_type_1 R-HSA-179812 GRB2 events in EGFR signaling 10/1821 13/10654 3.6044554482127058e-6 1.01666150388319e-5 4.483256805331939e-6 1839/4893/685/2069/1950/6654/2885/1956/3845/3265 10 Poliovirus_type_1 R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 10/1821 13/10654 3.6044554482127058e-6 1.01666150388319e-5 4.483256805331939e-6 7531/7532/2810/7534/891/983/995/1111/7465/7529 10 Poliovirus_type_1 R-HSA-2682334 EPH-Ephrin signaling 34/1821 92/10654 3.769232934471194e-6 1.0608168673653643e-5 4.67797238477234e-6 1072/3984/71/5747/4627/3985/23385/4318/5921/6453/4313/2051/2041/6714/4067/2043/2047/5063/2534/9475/6386/998/8976/7525/6093/1213/8440/387/60/3265/5058/5062/1969/5879 34 Poliovirus_type_1 R-HSA-72163 mRNA Splicing - Major Pathway 56/1821 183/10654 4.179624320269065e-6 1.1737550651038835e-5 5.17600535017841e-6 10450/7536/23451/6635/5434/6432/8683/6431/27339/5430/9879/6428/27258/8106/3178/23450/3183/5093/10594/4686/6625/11338/1655/9343/3185/3190/2962/22938/988/10236/10250/4670/23020/10189/6434/3181/11193/51729/1660/2521/3191/27316/3187/1665/6634/51593/9775/3192/6427/3312/6426/10291/22916/56259/5725/1994 56 Poliovirus_type_1 R-HSA-2428928 IRS-related events triggered by IGF1R 23/1821 52/10654 4.312057628198844e-6 1.2083135397278936e-5 5.328400730497427e-6 5295/5170/4893/5290/3667/5291/2322/57761/2260/5289/10818/2261/8471/2264/208/6654/2885/8660/3845/2549/3265/30849/3480 23 Poliovirus_type_1 R-HSA-8934903 Receptor Mediated Mitophagy 9/1821 11/10654 4.831775695734249e-6 1.3510106012584485e-5 5.957663833077965e-6 1459/9140/1460/9474/1457/6714/8408/81631/84557 9 Poliovirus_type_1 R-HSA-9018519 Estrogen-dependent gene expression 48/1821 150/10654 5.191839029053947e-6 1.4485455645996834e-5 6.3877718744341115e-6 27161/3725/3838/596/5434/7090/5241/7031/8204/5430/5451/2625/10274/10735/192670/5885/1655/6667/7033/2099/4609/2962/8850/10524/1387/3320/2033/8243/9126/595/192669/3065/2066/23028/10498/3326/1025/2353/1386/6908/3169/3276/7392/26523/8202/2288/10728/2957 48 Poliovirus_type_1 R-HSA-389513 CTLA4 inhibitory signaling 13/1821 21/10654 5.308447081020526e-6 1.4746957516024694e-5 6.503088529380863e-6 207/5528/6714/5519/4067/10000/2534/208/7525/3932/5518/5515/5516 13 Poliovirus_type_1 R-HSA-445144 Signal transduction by L1 13/1821 21/10654 5.308447081020526e-6 1.4746957516024694e-5 6.503088529380863e-6 5604/1459/5594/1460/2260/8829/1457/3690/3685/1956/5058/5879/5595 13 Poliovirus_type_1 R-HSA-2424491 DAP12 signaling 16/1821 30/10654 6.462574445806668e-6 1.7876091117263507e-5 7.882968603423539e-6 5295/9402/4893/6464/5290/5335/5291/6850/2534/695/6654/2885/3932/3845/3265/5879 16 Poliovirus_type_1 R-HSA-4090294 SUMOylation of intracellular receptors 16/1821 30/10654 6.462574445806668e-6 1.7876091117263507e-5 7.882968603423539e-6 5241/5468/5465/4306/9759/8856/2099/10401/2908/6256/7329/367/6612/5914/7421/10062 16 Poliovirus_type_1 R-HSA-1500620 Meiosis 40/1821 118/10654 6.622661413393149e-6 1.827968000399094e-5 8.060942552084527e-6 4000/1017/7014/6118/10388/25913/8468/1019/5888/25777/23224/27127/93426/10274/7013/545/472/10735/56158/5885/644186/26277/641/9985/6119/23345/256126/10734/65057/8243/9126/7329/4001/50511/6847/672/3306/6117/23353/54386 40 Poliovirus_type_1 R-HSA-205043 NRIF signals cell death from the nucleus 11/1821 16/10654 6.654773474766004e-6 1.8329066258490126e-5 8.082720819553851e-6 4804/8878/23421/23385/7316/4803/7189/6233/7311/5599/7314 11 Poliovirus_type_1 R-HSA-5696395 Formation of Incision Complex in GG-NER 20/1821 43/10654 7.1163233294485744e-6 1.955850910801538e-5 8.624878460110495e-6 6118/8450/54778/7316/9978/6119/10401/1642/142/1069/7329/6233/7311/6612/6117/7334/1022/5886/7314/8451 20 Poliovirus_type_1 R-HSA-5696398 Nucleotide Excision Repair 38/1821 111/10654 8.609402307916293e-6 2.3611743776391708e-5 1.0412267068924521e-5 10450/6118/5434/27339/5430/10445/7515/8450/54778/7316/9978/10980/6119/4798/10401/1642/2033/142/10987/1069/7329/6233/2873/7311/6612/60/8533/8607/6117/7334/5981/7874/1022/5886/50813/7314/51138/8451 38 Poliovirus_type_1 R-HSA-169893 Prolonged ERK activation events 10/1821 14/10654 1.0672932738577846e-5 2.9147055720395854e-5 1.285321962272979e-5 5604/5594/673/10818/4914/4803/1398/1399/7529/5595 10 Poliovirus_type_1 R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 10/1821 14/10654 1.0672932738577846e-5 2.9147055720395854e-5 1.285321962272979e-5 23368/207/54971/10848/10000/7157/8626/208/7161/7159 10 Poliovirus_type_1 R-HSA-9613829 Chaperone Mediated Autophagy 13/1821 22/10654 1.0944499999466893e-5 2.9825497884382292e-5 1.3152397907448809e-5 1915/1080/10013/5116/6035/7316/3920/3320/6233/3326/7311/3312/7314 13 Poliovirus_type_1 R-HSA-5654733 Negative regulation of FGFR4 signaling 16/1821 31/10654 1.1242895994947404e-5 3.0574035733095366e-5 1.3482486869357314e-5 5594/7316/673/6714/10818/8569/867/2264/6233/2885/7311/5518/7314/5595/5515/5516 16 Poliovirus_type_1 R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 14/1821 25/10654 1.1732278347393295e-5 3.183769850482096e-5 1.4039734753667323e-5 10694/79861/10575/10382/7277/10381/10576/908/6950/7846/347733/10574/10383/22948 14 Poliovirus_type_1 R-HSA-350054 Notch-HLH transcription pathway 15/1821 28/10654 1.1761026243209343e-5 3.1848661402304294e-5 1.4044569153766136e-5 8841/2648/55869/10013/4854/9759/9612/10014/22938/8850/1387/6907/3066/3065/4851 15 Poliovirus_type_1 R-HSA-8986944 Transcriptional Regulation by MECP2 25/1821 62/10654 1.241368268929228e-5 3.354557020230136e-5 1.4792869143148697e-5 818/27161/815/8841/5468/6446/817/9212/192670/4233/9612/2289/5566/6907/3064/5728/816/192669/3066/3065/3654/25942/26523/801/814 25 Poliovirus_type_1 R-HSA-112399 IRS-mediated signalling 21/1821 48/10654 1.3797220914033306e-5 3.720631330165049e-5 1.6407177479801774e-5 5295/5170/4893/5290/3667/5291/2322/57761/2260/5289/10818/2261/2264/208/6654/2885/8660/3845/2549/3265/30849 21 Poliovirus_type_1 R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 18/1821 38/10654 1.4908003422163837e-5 4.011777956402752e-5 1.7691070976746453e-5 1072/9049/6775/9987/3313/6175/3185/6647/6950/3458/3181/998/6648/4001/4282/5062/5721/829 18 Poliovirus_type_1 R-HSA-111932 CaMK IV-mediated phosphorylation of CREB 9/1821 12/10654 1.637668619142465e-5 4.361476962964127e-5 1.9233167775922817e-5 818/815/3838/817/10645/84254/816/801/814 9 Poliovirus_type_1 R-HSA-170968 Frs2-mediated activation 9/1821 12/10654 1.637668619142465e-5 4.361476962964127e-5 1.9233167775922817e-5 5604/5594/673/10818/4914/4803/1399/7529/5595 9 Poliovirus_type_1 R-HSA-389359 CD28 dependent Vav1 pathway 9/1821 12/10654 1.637668619142465e-5 4.361476962964127e-5 1.9233167775922817e-5 5063/2534/998/2885/7409/3932/5058/5062/5879 9 Poliovirus_type_1 R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 9/1821 12/10654 1.637668619142465e-5 4.361476962964127e-5 1.9233167775922817e-5 834/835/472/843/7157/8626/7161/839/317 9 Poliovirus_type_1 R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 9/1821 12/10654 1.637668619142465e-5 4.361476962964127e-5 1.9233167775922817e-5 5295/5290/5291/4067/23533/3717/5294/8660/2549 9 Poliovirus_type_1 R-HSA-72172 mRNA Splicing 56/1821 191/10654 1.7155723376244563e-5 4.5595314292740704e-5 2.010654503130128e-5 10450/7536/23451/6635/5434/6432/8683/6431/27339/5430/9879/6428/27258/8106/3178/23450/3183/5093/10594/4686/6625/11338/1655/9343/3185/3190/2962/22938/988/10236/10250/4670/23020/10189/6434/3181/11193/51729/1660/2521/3191/27316/3187/1665/6634/51593/9775/3192/6427/3312/6426/10291/22916/56259/5725/1994 56 Poliovirus_type_1 R-HSA-5626467 RHO GTPases activate IQGAPs 16/1821 32/10654 1.8931043987687247e-5 5.021011460931865e-5 2.2141571915423684e-5 79861/71/1499/10382/7277/10381/7846/999/347733/998/10788/10383/60/801/5879/4221 16 Poliovirus_type_1 R-HSA-8876384 Listeria monocytogenes entry into host cells 12/1821 20/10654 1.950606629017486e-5 5.162899270643818e-5 2.2767266392941588e-5 1499/7316/4233/6714/867/999/6455/30011/6233/2885/7311/7314 12 Poliovirus_type_1 R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 15/1821 29/10654 2.0522966510610522e-5 5.4098371844942664e-5 2.385620905334126e-5 11022/5434/8468/5430/91646/122402/56165/55124/84944/3320/54514/54456/143689/9271/136991 15 Poliovirus_type_1 R-HSA-933541 TRAF6 mediated IRF7 activation 15/1821 29/10654 2.0522966510610522e-5 5.4098371844942664e-5 2.385620905334126e-5 3665/7186/29110/57506/7706/23586/1387/2033/64135/3661/7189/10010/84282/9641/3456 15 Poliovirus_type_1 R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 18/1821 39/10654 2.3288451059034597e-5 6.108425902469599e-5 2.693683383556069e-5 10694/26224/8841/2629/10575/10576/908/6774/26272/26270/6950/55294/26190/7157/10574/54461/22948/8877 18 Poliovirus_type_1 R-HSA-390450 Folding of actin by CCT/TriC 8/1821 10/10654 2.3315326175446413e-5 6.108425902469599e-5 2.693683383556069e-5 10694/10575/10576/908/6950/10574/60/22948 8 Poliovirus_type_1 R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 8/1821 10/10654 2.3315326175446413e-5 6.108425902469599e-5 2.693683383556069e-5 2308/2309/4303/8850/1387/10628/2033/23411 8 Poliovirus_type_1 R-HSA-390466 Chaperonin-mediated protein folding 33/1821 95/10654 2.350348560305793e-5 6.145231834146383e-5 2.7099140014201523e-5 10694/26224/6000/8841/79861/2629/1459/10575/10382/1460/7277/10381/10576/908/8786/6774/1457/26272/26270/6950/7846/347733/55294/26190/7157/2771/10574/10383/60/54461/22948/8877/9628 33 Poliovirus_type_1 R-HSA-111933 Calmodulin induced events 17/1821 36/10654 2.707656682846281e-5 7.041677498395768e-5 3.1052271031266305e-5 818/815/3838/5567/817/5578/5568/5582/10645/5566/84254/816/5613/5577/5580/801/814 17 Poliovirus_type_1 R-HSA-111997 CaM pathway 17/1821 36/10654 2.707656682846281e-5 7.041677498395768e-5 3.1052271031266305e-5 818/815/3838/5567/817/5578/5568/5582/10645/5566/84254/816/5613/5577/5580/801/814 17 Poliovirus_type_1 R-HSA-111447 Activation of BAD and translocation to mitochondria 10/1821 15/10654 2.709598168506052e-5 7.041677498395768e-5 3.1052271031266305e-5 596/7531/572/7532/207/2810/7534/10000/208/7529 10 Poliovirus_type_1 R-HSA-202433 Generation of second messenger molecules 16/1821 33/10654 3.094365281987565e-5 8.005318728754393e-5 3.530171992591051e-5 9402/5335/4690/3123/3126/3115/3122/920/5063/7454/3702/3932/3127/3125/5058/5062 16 Poliovirus_type_1 R-HSA-5654726 Negative regulation of FGFR1 signaling 16/1821 33/10654 3.094365281987565e-5 8.005318728754393e-5 3.530171992591051e-5 5594/2260/7316/673/6714/10818/8569/867/6233/2885/7311/5518/7314/5595/5515/5516 16 Poliovirus_type_1 R-HSA-68875 Mitotic Prophase 44/1821 142/10654 3.0990333946070144e-5 8.005318728754393e-5 3.530171992591051e-5 4000/23165/4926/81929/5903/55706/7175/5579/9631/91754/5578/5594/5925/348995/79023/57122/23636/10762/23511/891/53371/983/23279/4927/9688/79902/8615/5519/9883/23225/8086/2010/4001/9972/5518/5347/8021/129401/55746/7112/8480/5595/5515/5516 44 Poliovirus_type_1 R-HSA-112043 PLC beta mediated events 22/1821 54/10654 3.376867145736398e-5 8.705563501708434e-5 3.8389647551529584e-5 818/815/3838/5321/5567/817/5578/5594/5568/5582/3708/10768/10645/5566/84254/816/5613/2771/5577/5580/801/814 22 Poliovirus_type_1 R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 15/1821 30/10654 3.45833585754142e-5 8.893602613084466e-5 3.921885926312206e-5 11065/7319/7321/7316/7317/7322/7347/7328/7324/6233/7311/7874/7332/997/7314 15 Poliovirus_type_1 R-HSA-210993 Tie2 Signaling 11/1821 18/10654 3.463606293070909e-5 8.893602613084466e-5 3.921885926312206e-5 5295/4893/6464/5290/5291/7010/6654/2885/3845/3265/284 11 Poliovirus_type_1 R-HSA-186797 Signaling by PDGF 23/1821 58/10654 3.76800654360827e-5 9.655984959664135e-5 4.258080011611313e-5 5295/4893/5290/5335/5291/5340/4690/5921/1280/6778/6774/6772/6714/5159/6654/2885/1398/8440/9564/3845/3265/1399/5156 23 Poliovirus_type_1 R-HSA-451927 Interleukin-2 family signaling 19/1821 44/10654 4.4063287585530796e-5 1.1247045088663208e-4 4.959703032034733e-5 5295/6464/5290/1437/5291/6775/1439/1438/6774/6850/6772/8503/3558/3717/6654/2885/3716/3932/2185 19 Poliovirus_type_1 R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 19/1821 44/10654 4.4063287585530796e-5 1.1247045088663208e-4 4.959703032034733e-5 23368/834/835/355/472/332/8797/1387/843/7157/8626/604/7161/839/7159/317/10397/8795/665 19 Poliovirus_type_1 R-HSA-202670 ERKs are inactivated 9/1821 13/10654 4.5114205363651617e-5 1.1492531761610067e-4 5.067957332301202e-5 5594/5528/5519/5598/5518/51231/5595/5515/5516 9 Poliovirus_type_1 R-HSA-112040 G-protein mediated events 22/1821 55/10654 4.728367021482181e-5 1.2021430159152921e-4 5.301190058341904e-5 818/815/3838/5321/5567/817/5578/5594/5568/5582/3708/10768/10645/5566/84254/816/5613/2771/5577/5580/801/814 22 Poliovirus_type_1 R-HSA-76002 Platelet activation, signaling and aggregation 70/1821 262/10654 5.0486010358145505e-5 1.2810328218828653e-4 5.649076998217691e-5 5295/5170/5590/351/1072/6464/5321/5290/5579/5291/7042/5340/5747/2316/207/3959/7422/5578/5594/5582/409/7277/3708/5583/7534/1950/335/308/6850/6714/6647/8503/146850/1432/3920/226/4067/23533/5588/81/3309/5880/2335/5294/2534/3690/408/55664/2768/1445/87/998/5894/2771/10487/6654/2885/1398/5580/7409/3932/387/5581/7040/9564/10916/801/7043/5879/5595 70 Poliovirus_type_1 R-HSA-8853659 RET signaling 18/1821 41/10654 5.3426303333920346e-5 1.352976522542698e-4 5.96633311970158e-5 5295/6464/5290/5335/5291/5567/5578/5568/6714/10818/5566/8503/5598/5979/6654/2885/8660/2549 18 Poliovirus_type_1 R-HSA-1226099 Signaling by FGFR in disease 24/1821 63/10654 5.5685362902018935e-5 1.4074202506020078e-4 6.206418156262174e-5 5295/5434/4893/11052/5290/5335/5430/9530/613/2260/4686/6774/6772/10818/2962/2261/11064/2264/6654/2885/3845/2549/3265/22916 24 Poliovirus_type_1 R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 10/1821 16/10654 6.116466203555127e-5 1.5368664593338322e-4 6.777247870975211e-5 5590/7316/7046/2280/6233/7048/7311/387/7040/7314 10 Poliovirus_type_1 R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 10/1821 16/10654 6.116466203555127e-5 1.5368664593338322e-4 6.777247870975211e-5 5295/5170/6464/5290/5291/6850/4067/2534/6654/2885 10 Poliovirus_type_1 R-HSA-9614657 FOXO-mediated transcription of cell death genes 10/1821 16/10654 6.116466203555127e-5 1.5368664593338322e-4 6.777247870975211e-5 2308/2309/65018/10018/356/4303/1387/6794/2033/604 10 Poliovirus_type_1 R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 14/1821 28/10654 6.32853080812857e-5 1.5870576287310752e-4 6.99858004585179e-5 10694/10575/10382/7277/10381/10576/908/6950/7846/347733/10574/10383/60/22948 14 Poliovirus_type_1 R-HSA-5655302 Signaling by FGFR1 in disease 17/1821 38/10654 6.422442920543432e-5 1.607481344578735e-4 7.088644204585497e-5 5295/4893/11052/5290/5335/9530/613/2260/6774/6772/10818/11064/6654/2885/3845/2549/3265 17 Poliovirus_type_1 R-HSA-442982 Ras activation upon Ca2+ influx through NMDA receptor 12/1821 22/10654 7.142629551921006e-5 1.7808219521133804e-4 7.853038701083872e-5 818/815/4893/817/816/1741/1742/1739/1740/3845/3265/801 12 Poliovirus_type_1 R-HSA-5205685 Pink/Parkin Mediated Mitophagy 12/1821 22/10654 7.142629551921006e-5 1.7808219521133804e-4 7.853038701083872e-5 65018/9140/8878/10452/9474/7316/81631/6233/9804/7311/84557/7314 12 Poliovirus_type_1 R-HSA-2559580 Oxidative Stress Induced Senescence 39/1821 125/10654 7.242024181782233e-5 1.7997611465848885e-4 7.936556442414273e-5 3725/1019/5601/5606/9448/1029/2146/6045/5594/50488/192670/8550/7316/9261/7867/4194/1432/5602/23512/1021/192669/7157/5609/6233/2353/1030/7311/5599/648/5600/23466/4217/26523/3456/5608/7314/5595/4193/23043 39 Poliovirus_type_1 R-HSA-1059683 Interleukin-6 signaling 8/1821 11/10654 7.260479412134538e-5 1.7997611465848885e-4 7.936556442414273e-5 9021/6774/6772/867/3717/3716/7297/3569 8 Poliovirus_type_1 R-HSA-4755510 SUMOylation of immune response proteins 8/1821 11/10654 7.260479412134538e-5 1.7997611465848885e-4 7.936556442414273e-5 8517/5970/4792/10401/7329/6612/9641/4791 8 Poliovirus_type_1 R-HSA-1251985 Nuclear signaling by ERBB4 15/1821 32/10654 8.95832760007025e-5 2.2121234246150486e-4 9.754984682472143e-5 1839/685/5241/2069/23118/23385/10413/6714/2099/145957/3084/2066/6285/9542/10718 15 Poliovirus_type_1 R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 15/1821 32/10654 8.95832760007025e-5 2.2121234246150486e-4 9.754984682472143e-5 10694/79861/10575/10382/7277/10381/10576/908/6950/7846/347733/10574/10383/60/22948 15 Poliovirus_type_1 R-HSA-391251 Protein folding 33/1821 101/10654 9.446164071951228e-5 2.3281272445019373e-4 1.0266536376881682e-4 10694/26224/6000/8841/79861/2629/1459/10575/10382/1460/7277/10381/10576/908/8786/6774/1457/26272/26270/6950/7846/347733/55294/26190/7157/2771/10574/10383/60/54461/22948/8877/9628 33 Poliovirus_type_1 R-HSA-909733 Interferon alpha/beta signaling 25/1821 69/10654 1.0267028955398542e-4 2.5256107487612065e-4 1.113739581340943e-4 3665/51447/10379/10410/9021/9636/11274/2634/3662/3394/3663/3664/3434/6772/8651/3659/1958/3661/4599/3716/3456/6773/7297/5696/3660 25 Poliovirus_type_1 R-HSA-399955 SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion 9/1821 14/10654 1.0710849608878446e-4 2.6247690391339003e-4 1.1574662375013733e-4 5361/10371/8829/55558/2534/91584/5362/5879/2242 9 Poliovirus_type_1 R-HSA-418885 DCC mediated attractive signaling 9/1821 14/10654 1.0710849608878446e-4 2.6247690391339003e-4 1.1574662375013733e-4 5747/4690/1793/6714/2534/998/8976/1630/5879 9 Poliovirus_type_1 R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 21/1821 54/10654 1.133569974735057e-4 2.7726218167618377e-4 0.00012226661067750542 10450/5434/27339/5430/8450/7316/9978/10980/1642/2033/10987/6233/2873/7311/8533/7874/1022/50813/7314/51138/8451 21 Poliovirus_type_1 R-HSA-373760 L1CAM interactions 37/1821 119/10654 1.1887906001305434e-4 2.902180082515664e-4 1.2797984929635039e-4 9252/79861/71/5604/1459/10382/5594/1460/7277/10381/2260/8829/1457/6714/27330/7846/347733/3690/6195/6386/1741/1742/1739/6709/3685/6196/1213/10383/1956/60/6197/8986/3312/5058/8506/5879/5595 37 Poliovirus_type_1 R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 10/1821 17/10654 1.2577922254988644e-4 3.06482831506245e-4 1.3515228370697182e-4 2308/857/2309/4303/1027/1026/4089/9314/4088/4087 10 Poliovirus_type_1 R-HSA-6783783 Interleukin-10 signaling 19/1821 47/10654 1.2981501265563018e-4 3.1571990813793833e-4 1.3922563422848127e-4 3557/7124/1437/3593/3553/2919/3383/3576/2920/6352/6774/3606/7132/3552/3716/6347/7297/3569/3554 19 Poliovirus_type_1 R-HSA-6806834 Signaling by MET 27/1821 79/10654 1.723821667355515e-4 4.1845689815842913e-4 1.8453041934224964e-4 5295/4893/6464/5290/5747/1280/7316/6774/4233/6714/3910/5795/867/6455/2335/6654/30011/6233/2885/1398/7311/3845/2549/3265/1399/7314/5879 27 Poliovirus_type_1 R-HSA-73893 DNA Damage Bypass 19/1821 48/10654 1.807893334279354e-4 4.3804032103121946e-4 1.931662842324597e-4 6118/9636/7706/8450/7316/9978/9100/7415/6119/51455/1642/5429/9246/6233/7311/6117/5981/7314/8451 19 Poliovirus_type_1 R-HSA-210990 PECAM1 interactions 8/1821 12/10654 1.8506100998118708e-4 4.458759661042059e-4 1.9662163382162524e-4 5335/6714/4067/2534/3690/7525/3685/3932 8 Poliovirus_type_1 R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 8/1821 12/10654 1.8506100998118708e-4 4.458759661042059e-4 1.9662163382162524e-4 23368/355/8797/7157/8626/7161/7159/8795 8 Poliovirus_type_1 R-HSA-9634600 Regulation of glycolysis by fructose 2,6-bisphosphate metabolism 8/1821 12/10654 1.8506100998118708e-4 4.458759661042059e-4 1.9662163382162524e-4 5567/5568/5528/5566/5519/5518/5515/5516 8 Poliovirus_type_1 R-HSA-354192 Integrin alphaIIb beta3 signaling 13/1821 27/10654 1.8894698992033364e-4 4.5270013012511164e-4 1.996309421971829e-4 5170/6464/5747/207/6850/6714/2335/3690/1445/6654/2885/1398/9564 13 Poliovirus_type_1 R-HSA-9006921 Integrin signaling 13/1821 27/10654 1.8894698992033364e-4 4.5270013012511164e-4 1.996309421971829e-4 5170/6464/5747/207/6850/6714/2335/3690/1445/6654/2885/1398/9564 13 Poliovirus_type_1 R-HSA-912526 Interleukin receptor SHC signaling 13/1821 27/10654 1.8894698992033364e-4 4.5270013012511164e-4 1.996309421971829e-4 5295/6464/5290/1437/5291/1439/1438/8503/3558/3717/6654/2885/3716 13 Poliovirus_type_1 R-HSA-383280 Nuclear Receptor transcription pathway 20/1821 52/10654 1.958407262917031e-4 4.6834637512060354e-4 2.0653059700716667e-4 5241/7182/5468/5465/2100/4306/9970/9612/8856/2099/5467/2908/3164/2103/6256/29982/367/5914/7421/10062 20 Poliovirus_type_1 R-HSA-5654727 Negative regulation of FGFR2 signaling 15/1821 34/10654 2.0889089770783958e-4 4.986303095285281e-4 2.1988515548193645e-4 5594/7316/673/6714/10818/8569/867/6233/2885/7311/5518/7314/5595/5515/5516 15 Poliovirus_type_1 R-HSA-8940973 RUNX2 regulates osteoblast differentiation 12/1821 24/10654 2.1326728010243878e-4 5.081359039778994e-4 2.240769165391905e-4 25/8841/23462/5594/3280/5925/10013/10413/6714/7525/367/5595 12 Poliovirus_type_1 R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 9/1821 15/10654 2.2712726769437067e-4 5.342464380621237e-4 2.3559109595651202e-4 1499/1452/5528/5519/2932/324/5518/5515/5516 9 Poliovirus_type_1 R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 9/1821 15/10654 2.2712726769437067e-4 5.342464380621237e-4 2.3559109595651202e-4 1499/1452/5528/5519/2932/324/5518/5515/5516 9 Poliovirus_type_1 R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 9/1821 15/10654 2.2712726769437067e-4 5.342464380621237e-4 2.3559109595651202e-4 1499/1452/5528/5519/2932/324/5518/5515/5516 9 Poliovirus_type_1 R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 9/1821 15/10654 2.2712726769437067e-4 5.342464380621237e-4 2.3559109595651202e-4 1499/1452/5528/5519/2932/324/5518/5515/5516 9 Poliovirus_type_1 R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 9/1821 15/10654 2.2712726769437067e-4 5.342464380621237e-4 2.3559109595651202e-4 1499/1452/5528/5519/2932/324/5518/5515/5516 9 Poliovirus_type_1 R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 9/1821 15/10654 2.2712726769437067e-4 5.342464380621237e-4 2.3559109595651202e-4 1499/1452/5528/5519/2932/324/5518/5515/5516 9 Poliovirus_type_1 R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 9/1821 15/10654 2.2712726769437067e-4 5.342464380621237e-4 2.3559109595651202e-4 7316/4233/867/6455/30011/6233/2885/7311/7314 9 Poliovirus_type_1 R-HSA-6807878 COPI-mediated anterograde transport 32/1821 101/10654 2.2791535032223e-4 5.351236549460008e-4 2.3597792958298191e-4 11014/79861/11258/1783/10382/93661/55860/830/7277/10381/10671/1780/1781/8655/84516/1639/832/10121/8615/8775/7846/347733/51143/1314/3630/10540/6709/10383/140735/829/51164/1778 32 Poliovirus_type_1 R-HSA-111471 Apoptotic factor-mediated response 10/1821 18/10654 2.3970817207385816e-4 5.607692083542707e-4 2.472870626036554e-4 1029/842/5594/54205/836/840/331/317/578/5595 10 Poliovirus_type_1 R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 10/1821 18/10654 2.3970817207385816e-4 5.607692083542707e-4 2.472870626036554e-4 2810/891/983/6790/2033/995/1874/7157/10498/3276 10 Poliovirus_type_1 R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 16/1821 38/10654 2.5026819269163614e-4 5.844125006875344e-4 2.577132419021425e-4 6595/6597/1459/6045/1460/6598/6599/1457/8289/10138/2033/6605/6602/648/6601/23466 16 Poliovirus_type_1 R-HSA-182971 EGFR downregulation 14/1821 31/10654 2.511606688030193e-4 5.854359893075802e-4 2.581645781928818e-4 1839/685/2069/7316/1950/867/6455/998/30011/6233/2885/7311/1956/7314 14 Poliovirus_type_1 R-HSA-73894 DNA Repair 82/1821 334/10654 2.765931868177003e-4 6.435534617473208e-4 2.837931234686646e-4 10450/1017/7014/6118/2176/25/25913/3838/5434/5893/151987/5888/5883/322/328/27339/5430/10445/7515/7013/5531/51548/9636/545/472/7706/51567/580/5591/8450/54778/7316/9978/26277/641/9100/7415/10980/6119/51455/3364/10524/4798/10401/1642/5429/65057/2033/142/1111/10987/7157/1069/7329/4255/9246/6233/2873/672/7311/6047/9025/2189/6612/60/5536/8533/8607/6117/2175/5599/7334/5981/7874/54386/5810/1022/5886/50813/7314/51138/8451 82 Poliovirus_type_1 R-HSA-110056 MAPK3 (ERK1) activation 7/1821 10/10654 3.125309253023215e-4 7.245546091990871e-4 3.1951287327386147e-4 5604/983/3717/3716/7297/3569/5595 7 Poliovirus_type_1 R-HSA-442729 CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde 7/1821 10/10654 3.125309253023215e-4 7.245546091990871e-4 3.1951287327386147e-4 818/3838/10645/84254/816/801/814 7 Poliovirus_type_1 R-HSA-5654708 Downstream signaling of activated FGFR3 12/1821 25/10654 3.466828513151825e-4 8.008498124467208e-4 3.5315740371665456e-4 5295/4893/6464/5290/5335/10818/2261/6654/2885/3845/2549/3265 12 Poliovirus_type_1 R-HSA-9620244 Long-term potentiation 12/1821 25/10654 3.466828513151825e-4 8.008498124467208e-4 3.5315740371665456e-4 818/815/817/6714/3084/816/2066/1741/1742/1739/1740/801 12 Poliovirus_type_1 R-HSA-74752 Signaling by Insulin receptor 26/1821 78/10654 3.544259433498265e-4 8.172719874381508e-4 3.60399226831572e-4 5295/5170/3643/4893/6464/5290/3667/5291/5594/2322/57761/2260/5289/10818/2261/2264/3630/208/6654/2885/8660/3845/2549/3265/30849/5595 26 Poliovirus_type_1 R-HSA-5656169 Termination of translesion DNA synthesis 14/1821 32/10654 3.7683197431593007e-4 8.6429967062853e-4 3.8113741549092013e-4 6118/9636/7706/7316/9100/6119/51455/5429/9246/6233/7311/6117/5981/7314 14 Poliovirus_type_1 R-HSA-8941326 RUNX2 regulates bone development 14/1821 32/10654 3.7683197431593007e-4 8.6429967062853e-4 3.8113741549092013e-4 25/8841/23462/5594/3280/5925/10013/9759/10413/6714/4089/7525/367/5595 14 Poliovirus_type_1 R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 14/1821 32/10654 3.7683197431593007e-4 8.6429967062853e-4 3.8113741549092013e-4 5295/4690/640/3708/6850/10768/4067/2534/695/6654/30011/2885/7409/801 14 Poliovirus_type_1 R-HSA-5655332 Signaling by FGFR3 in disease 11/1821 22/10654 3.930521409460474e-4 8.983053363110906e-4 3.961331767653334e-4 5295/4893/5290/5335/10818/2261/6654/2885/3845/2549/3265 11 Poliovirus_type_1 R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 11/1821 22/10654 3.930521409460474e-4 8.983053363110906e-4 3.961331767653334e-4 5295/4893/5290/5335/10818/2261/6654/2885/3845/2549/3265 11 Poliovirus_type_1 R-HSA-111885 Opioid Signalling 29/1821 91/10654 3.944418277285285e-4 8.998858689240235e-4 3.968301573794232e-4 818/815/3838/5321/5567/817/5578/5594/5568/5582/3708/5528/10768/10645/5566/84254/5519/816/5613/5499/2771/5577/5580/5518/801/1020/814/5515/5516 29 Poliovirus_type_1 R-HSA-111461 Cytochrome c-mediated apoptotic response 8/1821 13/10654 4.089758973692447e-4 9.297529659769953e-4 4.100008996182905e-4 842/5594/54205/836/840/331/317/5595 8 Poliovirus_type_1 R-HSA-171007 p38MAPK events 8/1821 13/10654 4.089758973692447e-4 9.297529659769953e-4 4.100008996182905e-4 4893/9261/6714/7867/1432/3845/5600/3265 8 Poliovirus_type_1 R-HSA-110320 Translesion Synthesis by POLH 10/1821 19/10654 4.2876852926623403e-4 9.713227315011876e-4 4.2833226492233165e-4 6118/7316/7415/6119/5429/6233/7311/6117/5981/7314 10 Poliovirus_type_1 R-HSA-3928664 Ephrin signaling 10/1821 19/10654 4.2876852926623403e-4 9.713227315011876e-4 4.2833226492233165e-4 2051/6714/2047/5063/2534/6386/8440/5058/5062/5879 10 Poliovirus_type_1 R-HSA-437239 Recycling pathway of L1 18/1821 47/10654 4.2969555643369536e-4 9.717150390228655e-4 4.285052640336021e-4 9252/79861/71/10382/5594/7277/10381/6714/27330/7846/347733/6195/6196/1213/10383/60/6197/8986 18 Poliovirus_type_1 R-HSA-110312 Translesion synthesis by REV1 9/1821 16/10654 4.4050776068428154e-4 9.94421197061364e-4 4.3851818742651316e-4 6118/7316/6119/51455/6233/7311/6117/5981/7314 9 Poliovirus_type_1 R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 26/1821 79/10654 4.437304375379648e-4 9.981998847930832e-4 4.401845067888326e-4 10450/6118/5434/27339/5430/7515/8450/7316/9978/10980/6119/1642/2033/10987/6233/2873/7311/8533/6117/5981/7874/1022/50813/7314/51138/8451 26 Poliovirus_type_1 R-HSA-8852135 Protein ubiquitination 26/1821 79/10654 4.437304375379648e-4 9.981998847930832e-4 4.401845067888326e-4 11065/7319/7321/79139/79577/5591/7323/7316/7317/51255/8915/7415/7322/9810/7347/7328/7324/6233/7311/10670/7334/7874/7332/997/80349/7314 26 Poliovirus_type_1 R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 27/1821 84/10654 5.304609842528372e-4 0.0011912268444284097 5.253052108867268e-4 6517/7124/1052/1019/8841/4790/5468/1051/6720/5465/5970/9612/9314/9968/1387/6907/9439/2033/9443/6256/10498/4023/23054/7040/51586/8202/10891 27 Poliovirus_type_1 R-HSA-2132295 MHC class II antigen presentation 36/1821 123/10654 5.391575545879924e-4 0.0012086505875894297 5.329887038489993e-4 164/79861/11258/1783/10382/93661/821/55860/830/3123/7277/10381/3126/10671/1780/3115/1781/3122/8655/84516/1639/832/10121/7846/347733/51143/10540/1213/10383/3127/3125/7879/140735/829/51164/1778 36 Poliovirus_type_1 R-HSA-180024 DARPP-32 events 12/1821 26/10654 5.443773895220406e-4 0.0012161221058819935 5.362834814227892e-4 5567/5568/5528/5566/5519/5499/5577/5518/801/1020/5515/5516 12 Poliovirus_type_1 R-HSA-6803529 FGFR2 alternative splicing 12/1821 26/10654 5.443773895220406e-4 0.0012161221058819935 5.362834814227892e-4 5434/23543/5430/3178/4686/3185/2962/4670/7072/3187/22916/5725 12 Poliovirus_type_1 R-HSA-109704 PI3K Cascade 17/1821 44/10654 5.468084480771289e-4 0.001219439601334635 5.377464249893454e-4 5295/5170/5290/3667/5291/2322/57761/2260/5289/10818/2261/2264/208/2885/8660/2549/30849 17 Poliovirus_type_1 R-HSA-8856828 Clathrin-mediated endocytosis 41/1821 146/10654 5.917860454541899e-4 0.0013174649612961154 5.809734834019862e-4 1839/685/71/5868/5286/4738/2069/409/1080/29978/29763/6453/7316/1950/920/273/10980/867/6455/408/10987/8976/30011/29979/6233/2885/2873/7311/1213/1956/60/8533/274/51429/3312/29993/50813/7314/50618/51138/11252 41 Poliovirus_type_1 R-HSA-5685938 HDR through Single Strand Annealing (SSA) 15/1821 37/10654 6.324402740757752e-4 0.0014055439884201278 6.198144246840629e-4 6118/25/5893/5888/5883/545/472/580/641/6119/3364/10524/672/6117/5810 15 Poliovirus_type_1 R-HSA-373753 Nephrin family interactions 11/1821 23/10654 6.376848166100101e-4 0.001414760290207062 6.238786139494618e-4 5295/5290/5291/4690/81/2534/87/8976/23607/6709/8440 11 Poliovirus_type_1 R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 10/1821 20/10654 7.268136937744139e-4 0.0016097299850089683 7.098560221345335e-4 2648/23462/3280/22938/8850/1387/4088/2033/2324/4851 10 Poliovirus_type_1 R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 7/1821 11/10654 7.324016548690262e-4 0.0016137875779934612 7.116453326662604e-4 64344/7422/3091/1387/2033/2034/405 7 Poliovirus_type_1 R-HSA-8851805 MET activates RAS signaling 7/1821 11/10654 7.324016548690262e-4 0.0016137875779934612 7.116453326662604e-4 4893/6464/4233/6654/2885/3845/3265 7 Poliovirus_type_1 R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 7/1821 11/10654 7.324016548690262e-4 0.0016137875779934612 7.116453326662604e-4 4893/4915/10818/6654/2885/3845/3265 7 Poliovirus_type_1 R-HSA-196299 Beta-catenin phosphorylation cascade 9/1821 17/10654 7.945773660854756e-4 0.0017388968164417284 7.668157942742505e-4 1499/1452/5528/5519/2932/324/5518/5515/5516 9 Poliovirus_type_1 R-HSA-5655862 Translesion synthesis by POLK 9/1821 17/10654 7.945773660854756e-4 0.0017388968164417284 7.668157942742505e-4 6118/7316/6119/51455/6233/7311/6117/5981/7314 9 Poliovirus_type_1 R-HSA-5656121 Translesion synthesis by POLI 9/1821 17/10654 7.945773660854756e-4 0.0017388968164417284 7.668157942742505e-4 6118/7316/6119/51455/6233/7311/6117/5981/7314 9 Poliovirus_type_1 R-HSA-8934593 Regulation of RUNX1 Expression and Activity 9/1821 17/10654 7.945773660854756e-4 0.0017388968164417284 7.668157942742505e-4 27161/894/192670/6714/1021/595/192669/5371/26523 9 Poliovirus_type_1 R-HSA-428540 Activation of RAC1 8/1821 14/10654 8.11465765743189e-4 0.0017462093022420208 7.700404419670013e-4 4690/56924/5063/6654/8440/5058/5062/5879 8 Poliovirus_type_1 R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 8/1821 14/10654 8.11465765743189e-4 0.0017462093022420208 7.700404419670013e-4 1452/5528/5519/2932/324/5518/5515/5516 8 Poliovirus_type_1 R-HSA-4839744 truncated APC mutants destabilize the destruction complex 8/1821 14/10654 8.11465765743189e-4 0.0017462093022420208 7.700404419670013e-4 1452/5528/5519/2932/324/5518/5515/5516 8 Poliovirus_type_1 R-HSA-4839748 AMER1 mutants destabilize the destruction complex 8/1821 14/10654 8.11465765743189e-4 0.0017462093022420208 7.700404419670013e-4 1452/5528/5519/2932/324/5518/5515/5516 8 Poliovirus_type_1 R-HSA-5467337 APC truncation mutants have impaired AXIN binding 8/1821 14/10654 8.11465765743189e-4 0.0017462093022420208 7.700404419670013e-4 1452/5528/5519/2932/324/5518/5515/5516 8 Poliovirus_type_1 R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 8/1821 14/10654 8.11465765743189e-4 0.0017462093022420208 7.700404419670013e-4 1452/5528/5519/2932/324/5518/5515/5516 8 Poliovirus_type_1 R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 8/1821 14/10654 8.11465765743189e-4 0.0017462093022420208 7.700404419670013e-4 1452/5528/5519/2932/324/5518/5515/5516 8 Poliovirus_type_1 R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 8/1821 14/10654 8.11465765743189e-4 0.0017462093022420208 7.700404419670013e-4 23368/332/7157/8626/604/7161/7159/10397 8 Poliovirus_type_1 R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 8/1821 14/10654 8.11465765743189e-4 0.0017462093022420208 7.700404419670013e-4 8841/9612/5566/6907/3065/25942/801/814 8 Poliovirus_type_1 R-HSA-9005895 Pervasive developmental disorders 8/1821 14/10654 8.11465765743189e-4 0.0017462093022420208 7.700404419670013e-4 8841/9612/5566/6907/3065/25942/801/814 8 Poliovirus_type_1 R-HSA-5654716 Downstream signaling of activated FGFR4 12/1821 27/10654 8.287217092034072e-4 0.0017803704719386532 7.8510477714007e-4 5295/4893/6464/5290/5335/10818/2264/6654/2885/3845/2549/3265 12 Poliovirus_type_1 R-HSA-1474165 Reproduction 40/1821 144/10654 8.666461761424601e-4 0.0018587469568180216 8.196671076572878e-4 4000/1017/7014/6118/10388/25913/8468/1019/5888/25777/23224/27127/93426/10274/7013/545/472/10735/56158/5885/644186/26277/641/9985/6119/23345/256126/10734/65057/8243/9126/7329/4001/50511/6847/672/3306/6117/23353/54386 40 Poliovirus_type_1 R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 16/1821 42/10654 9.466970177756866e-4 0.00202706388025392 8.938912215402533e-4 8945/7090/1499/207/7534/7316/324/3065/7088/208/6233/7514/7311/331/7314/4221 16 Poliovirus_type_1 R-HSA-5627123 RHO GTPases activate PAKs 11/1821 24/10654 9.96807347501036e-4 0.002127292501537807 9.380898704262103e-4 3984/4627/2316/4771/5063/998/5058/801/5062/5500/5879 11 Poliovirus_type_1 R-HSA-982772 Growth hormone receptor signaling 11/1821 24/10654 9.96807347501036e-4 0.002127292501537807 9.380898704262103e-4 3667/9021/5594/6774/6772/8651/4067/3717/8660/8835/5595 11 Poliovirus_type_1 R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission 53/1821 206/10654 0.00103369911833917 0.002202377129816843 9.71200563554853e-4 818/5170/5563/815/3838/4893/79861/5579/5567/817/5578/10382/5594/5568/51422/5582/7277/53632/10381/10645/6714/23229/5566/84254/5571/27330/7846/347733/3084/6195/4137/816/2066/5613/1741/2771/1742/5577/1739/6196/5562/10383/1740/6197/3845/3265/5564/801/5565/814/5879/5595/4193 53 Poliovirus_type_1 R-HSA-8953750 Transcriptional Regulation by E2F6 14/1821 35/10654 0.0011161421281069932 0.0023741042955939175 0.001046928520371333 5888/2146/6045/84108/79813/4149/10138/23512/1111/672/648/317/10919/6241 14 Poliovirus_type_1 R-HSA-6807004 Negative regulation of MET activity 10/1821 21/10654 0.0011764268533578494 0.002498211225664362 0.0011016569857161863 7316/4233/5795/867/6455/30011/6233/2885/7311/7314 10 Poliovirus_type_1 R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 15/1821 39/10654 0.0012091817517396173 0.0025635448651190242 0.0011304677041887006 6118/9636/7706/7316/9100/7415/6119/51455/5429/9246/6233/7311/6117/5981/7314 15 Poliovirus_type_1 R-HSA-2172127 DAP12 interactions 16/1821 43/10654 0.001271720149539753 0.0026917032393378353 0.0011869827685618646 5295/9402/4893/6464/5290/5335/5291/6850/2534/695/6654/2885/3932/3845/3265/5879 16 Poliovirus_type_1 R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 20/1821 59/10654 0.001298474459633401 0.0027438255384712356 0.0012099675723935058 7319/7321/79139/79577/5591/7323/7316/51255/8915/7415/7322/9810/7324/6233/7311/10670/7334/7332/80349/7314 20 Poliovirus_type_1 R-HSA-9639288 Amino acids regulate mTORC1 19/1821 55/10654 0.0013173223093699222 0.0027790973106020123 0.0012255216591605788 81929/389541/58528/153129/64223/10325/8649/6009/57600/10542/2475/55004/10670/201163/96459/64121/57521/10641/28956 19 Poliovirus_type_1 R-HSA-1368082 RORA activates gene expression 9/1821 18/10654 0.0013494465600970955 0.0028422166927535232 0.001253355938170677 1374/6720/5465/1387/6907/2033/6256/10498/23054 9 Poliovirus_type_1 R-HSA-204998 Cell death signalling via NRAGE, NRIF and NADE 24/1821 76/10654 0.0013946188362827907 0.002932567177762671 0.0012931985431316338 4804/10018/7531/572/835/8878/23421/23385/6453/7316/4168/23229/50649/836/4803/7189/6654/6233/7409/7311/26574/5599/7314/5879 24 Poliovirus_type_1 R-HSA-381042 PERK regulates gene expression 13/1821 32/10654 0.0014087766022584827 0.002957513094969355 0.0013041991517565245 1965/5073/1051/3576/468/8894/3309/9451/6347/467/8570/167227/1968 13 Poliovirus_type_1 R-HSA-4419969 Depolymerisation of the Nuclear Lamina 8/1821 15/10654 0.001479281192084694 0.0031004771651986507 0.0013672432070615914 4000/5579/5578/891/983/2010/4001/7112 8 Poliovirus_type_1 R-HSA-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation 7/1821 12/10654 0.0014986785577120064 0.0031208346702597356 0.0013762204254136271 6697/2643/207/3320/4846/5593/801 7 Poliovirus_type_1 R-HSA-2029481 FCGR activation 7/1821 12/10654 0.0014986785577120064 0.0031208346702597356 0.0013762204254136271 2268/3055/6850/6714/4067/2534/7525 7 Poliovirus_type_1 R-HSA-5689877 Josephin domain DUBs 7/1821 12/10654 0.0014986785577120064 0.0031208346702597356 0.0013762204254136271 4287/7316/7415/6233/7311/5886/7314 7 Poliovirus_type_1 R-HSA-8984722 Interleukin-35 Signalling 7/1821 12/10654 0.0014986785577120064 0.0031208346702597356 0.0013762204254136271 6775/821/6774/6772/3717/3716/7297 7 Poliovirus_type_1 R-HSA-5619102 SLC transporter disorders 29/1821 99/10654 0.0017677380388996494 0.003675184406680078 0.0016206766400777772 23165/81929/5903/55706/7175/9631/6559/348995/79023/57122/23636/10762/23511/53371/3098/23279/4927/9688/79902/9883/10999/23225/682/8086/9972/8021/129401/55746/8480 29 Poliovirus_type_1 R-HSA-202427 Phosphorylation of CD3 and TCR zeta chains 10/1821 22/10654 0.0018292391137010216 0.0037969230556531668 0.0016743607448064272 3123/3126/3115/3122/920/5795/1445/3932/3127/3125 10 Poliovirus_type_1 R-HSA-2871809 FCERI mediated Ca+2 mobilization 13/1821 33/10654 0.0019653680132870623 0.004072925030750842 0.001796071631705896 9402/6464/5335/3708/6850/10768/4067/695/6654/2885/7409/3702/801 13 Poliovirus_type_1 R-HSA-176187 Activation of ATR in response to replication stress 14/1821 37/10654 0.0020968616022639924 0.004338450409820683 0.0019131625669047158 1017/4172/6118/5883/545/4174/993/4171/6119/3364/995/1111/6117/5810 14 Poliovirus_type_1 R-HSA-9609736 Assembly and cell surface presentation of NMDA receptors 15/1821 41/10654 0.0021744422032100533 0.004491756410156664 0.001980767189158956 818/815/79861/817/10382/7277/10381/7846/347733/816/1741/1742/1739/10383/1740 15 Poliovirus_type_1 R-HSA-5686938 Regulation of TLR by endogenous ligand 9/1821 19/10654 0.0021780567878448634 0.004492024319251246 0.001980885331261013 23643/6271/10333/7099/7096/6279/3146/929/7097 9 Poliovirus_type_1 R-HSA-9012852 Signaling by NOTCH3 17/1821 49/10654 0.002204928938599645 0.004538285597152642 0.0020012855518046855 2648/23462/3280/23385/7316/1950/4854/6772/22938/8850/1387/2033/6233/7311/1956/4851/7314 17 Poliovirus_type_1 R-HSA-3899300 SUMOylation of transcription cofactors 16/1821 45/10654 0.0022075291461712233 0.004538285597152642 0.0020012855518046855 8204/6045/4869/1655/9612/1387/10401/10521/1616/2033/7329/6612/25942/6294/648/10891 16 Potato_mop.top_virus R-HSA-6798695 Neutrophil degranulation 56/99 480/10654 6.429123963104717e-50 3.040975634548531e-47 2.564882086333356e-47 150372/1650/55004/23317/8904/3312/5908/3916/374395/5660/2040/5284/127829/79888/25798/4718/5878/719/154664/2683/4126/8673/2548/1088/8895/10396/968/9145/353189/54918/9218/11010/80331/10043/23200/84061/527/967/3920/326624/23385/5547/9545/6836/9342/10970/9522/8876/55754/2219/401258/684/5663/2357/4257/4680 56 Potato_mop.top_virus R-HSA-432722 Golgi Associated Vesicle Biogenesis 6/99 56/10654 1.2328120259929452e-5 0.0029156004414733153 0.002459135567638559 2580/3312/5878/9829/8673/164 6 Potato_virus_Y R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 109/350 112/10654 4.68157684751321e-165 4.1478770868967043e-162 2.5674753026888243e-162 6142/6158/6167/7458/7311/6204/8669/6223/25873/8664/6224/6146/51065/6154/3646/8662/6138/6141/10480/6144/8663/6202/6228/23521/6123/6203/51386/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/8894/6134/1965/6169/6160/6234/27335/6191/8665/6166/6128/6135/6201/6164/1981/140801/6161/51121/6132/6156/6155/6159/6147/8661/6175/8666/6235/6129/6218/6143/1973/9045/6217/6181/6187/6124/9669/6168/6207/6208/6222/6157/6137/1983/6176/6170/6209/1977/6139/6152/1974/200916/6136/1964/6193/6122/6173/6133/6210/6231/6229/11224/6205/8668/6233/1975/6165/1968/8667/6125/6230/6130 109 Potato_virus_Y R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 108/350 111/10654 1.984966472072506e-163 8.793401471281203e-161 5.4429870102619785e-161 6142/6158/6167/7458/7311/6204/8669/6223/25873/8664/6224/6146/51065/6154/3646/8662/6138/6141/10480/6144/26986/8663/6202/6228/23521/6123/6203/51386/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/8894/6134/1965/6169/6160/6234/27335/6191/8665/6166/6128/6135/6201/6164/1981/140801/6161/51121/6132/6156/6155/6159/6147/8661/6175/8666/6235/6129/6218/6143/1973/9045/6217/6181/6187/6124/6168/6207/6208/6222/6157/6137/6176/6170/6209/1977/6139/6152/1974/200916/6136/1964/6193/6122/6173/6133/6210/6231/6229/11224/6205/8668/6233/1975/6165/1968/8667/6125/6230/6130 108 Potato_virus_Y R-HSA-72613 Eukaryotic Translation Initiation 111/350 119/10654 7.4836297818035135e-162 1.6576239966694782e-159 1.0260450306104292e-159 6142/6158/6167/7458/7311/6204/8669/6223/25873/8664/6224/6146/51065/6154/3646/8662/6138/6141/10480/6144/26986/8663/6202/6228/23521/6123/6203/51386/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/8894/6134/1965/6169/6160/6234/27335/6191/8665/6166/6128/6135/6201/6164/1978/1981/140801/6161/51121/6132/6156/6155/6159/6147/8661/6175/8666/6235/6129/6218/6143/1973/9045/6217/6181/6187/6124/9669/6168/6207/6208/6222/6157/6137/1983/6176/6170/6209/1977/6139/6152/1974/200916/6136/1964/6193/6122/6173/6133/6210/6231/6229/11224/6205/8668/6233/1975/6165/1968/8667/6125/6230/6130 111 Potato_virus_Y R-HSA-72737 Cap-dependent Translation Initiation 111/350 119/10654 7.4836297818035135e-162 1.6576239966694782e-159 1.0260450306104292e-159 6142/6158/6167/7458/7311/6204/8669/6223/25873/8664/6224/6146/51065/6154/3646/8662/6138/6141/10480/6144/26986/8663/6202/6228/23521/6123/6203/51386/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/8894/6134/1965/6169/6160/6234/27335/6191/8665/6166/6128/6135/6201/6164/1978/1981/140801/6161/51121/6132/6156/6155/6159/6147/8661/6175/8666/6235/6129/6218/6143/1973/9045/6217/6181/6187/6124/9669/6168/6207/6208/6222/6157/6137/1983/6176/6170/6209/1977/6139/6152/1974/200916/6136/1964/6193/6122/6173/6133/6210/6231/6229/11224/6205/8668/6233/1975/6165/1968/8667/6125/6230/6130 111 Potato_virus_Y R-HSA-72689 Formation of a pool of free 40S subunits 98/350 101/10654 2.9515904412660784e-147 5.23021826192349e-145 3.2374286734728995e-145 6142/6158/6167/7311/6204/8669/6223/25873/8664/6224/6146/51065/6154/3646/8662/6138/6141/10480/6144/8663/6202/6228/23521/6123/6203/51386/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/6134/6169/6160/6234/27335/6191/8665/6166/6128/6135/6201/6164/140801/6161/51121/6132/6156/6155/6159/6147/8661/6175/8666/6235/6129/6218/6143/9045/6217/6181/6187/6124/6168/6207/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/1964/6193/6122/6173/6133/6210/6231/6229/11224/6205/8668/6233/6165/8667/6125/6230/6130 98 Potato_virus_Y R-HSA-168273 Influenza Viral RNA Transcription and Replication 108/350 134/10654 1.9656573935912477e-141 2.9026207512030756e-139 1.7966798281772638e-139 6142/6158/6167/23165/7311/6204/6223/25873/9883/9972/6224/6146/348995/51065/6154/6138/6141/6144/6202/6228/79023/23521/6123/6203/57122/23636/116832/5903/6227/9349/4736/23225/3921/6188/6189/6232/8021/6206/6194/6134/6169/10762/6160/6234/6191/55706/7175/6166/6128/6135/6201/129401/23511/6164/140801/6161/51121/6132/9631/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/53371/6181/6187/6124/55746/6168/6207/6208/6222/8086/6157/6137/6176/6170/6209/6139/6152/200916/6136/8480/6193/6122/6173/6133/23279/6210/4927/6231/6229/9688/11224/6205/6233/6165/6125/79902/6230/6130 108 Potato_virus_Y R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 92/350 95/10654 1.2198188348979994e-137 1.5439421253137536e-135 9.556776135065531e-136 6142/6158/6167/7311/6204/6223/25873/6224/6146/51065/6154/6138/6141/6144/26986/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/2107/2935/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/1981/23708/140801/6161/51121/4686/6132/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/5976/6217/6181/6187/6124/6168/6207/22916/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/6233/6165/6125/6230/6130 92 Potato_virus_Y R-HSA-168255 Influenza Life Cycle 108/350 144/10654 4.712432312488014e-135 5.219018786080476e-133 3.2304963615871785e-133 6142/6158/6167/23165/7311/6204/6223/25873/9883/9972/6224/6146/348995/51065/6154/6138/6141/6144/6202/6228/79023/23521/6123/6203/57122/23636/116832/5903/6227/9349/4736/23225/3921/6188/6189/6232/8021/6206/6194/6134/6169/10762/6160/6234/6191/55706/7175/6166/6128/6135/6201/129401/23511/6164/140801/6161/51121/6132/9631/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/53371/6181/6187/6124/55746/6168/6207/6208/6222/8086/6157/6137/6176/6170/6209/6139/6152/200916/6136/8480/6193/6122/6173/6133/23279/6210/4927/6231/6229/9688/11224/6205/6233/6165/6125/79902/6230/6130 108 Potato_virus_Y R-HSA-168254 Influenza Infection 109/350 155/10654 4.613528362686801e-131 4.541762365933895e-129 2.811284534455934e-129 6142/6158/6167/23165/7311/6204/6223/25873/9883/9972/6224/6146/348995/51065/6154/6138/6141/9636/6144/6202/6228/79023/23521/6123/6203/57122/23636/116832/5903/6227/9349/4736/23225/3921/6188/6189/6232/8021/6206/6194/6134/6169/10762/6160/6234/6191/55706/7175/6166/6128/6135/6201/129401/23511/6164/140801/6161/51121/6132/9631/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/53371/6181/6187/6124/55746/6168/6207/6208/6222/8086/6157/6137/6176/6170/6209/6139/6152/200916/6136/8480/6193/6122/6173/6133/23279/6210/4927/6231/6229/9688/11224/6205/6233/6165/6125/79902/6230/6130 109 Potato_virus_Y R-HSA-72764 Eukaryotic Translation Termination 87/350 93/10654 6.765855181901742e-126 5.994547691164943e-124 3.710537420811377e-124 6142/6158/6167/7311/6204/6223/25873/6224/6146/51065/6154/6138/6141/6144/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/2107/2935/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/23708/140801/6161/51121/6132/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/6181/6187/6124/6168/6207/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/6233/6165/6125/6230/6130 87 Potato_virus_Y R-HSA-156902 Peptide chain elongation 85/350 89/10654 3.634288917071069e-125 2.92725452774997e-123 1.8119277758794518e-123 6142/6158/6167/7311/6204/6223/25873/6224/6146/51065/6154/6138/6141/6144/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/140801/6161/51121/6132/6156/6155/1938/6159/6147/6175/6235/6129/6218/6143/9045/6217/6181/6187/6124/6168/6207/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/6233/6165/6125/6230/6130 85 Potato_virus_Y R-HSA-156842 Eukaryotic Translation Elongation 86/350 93/10654 3.281200214763741e-123 2.4226194919005617e-121 1.4995660630630783e-121 6142/6158/1937/6167/7311/6204/6223/25873/6224/6146/51065/6154/6138/6141/6144/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/140801/6161/51121/6132/6156/6155/1938/6159/6147/6175/6235/6129/6218/6143/9045/6217/6181/6187/6124/6168/6207/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/6233/6165/6125/6230/6130 86 Potato_virus_Y R-HSA-192823 Viral mRNA Translation 84/350 89/10654 2.3931184670000888e-122 1.6310022782785222e-120 1.0095665759571227e-120 6142/6158/6167/7311/6204/6223/25873/6224/6146/51065/6154/6138/6141/6144/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/140801/6161/51121/6132/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/6181/6187/6124/6168/6207/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/6233/6165/6125/6230/6130 84 Potato_virus_Y R-HSA-927802 Nonsense-Mediated Decay (NMD) 93/350 115/10654 3.0472739947783268e-121 1.799923172915732e-119 1.114126141248778e-119 6142/6158/6167/7311/6204/6223/25873/6224/6146/51065/6154/6138/6141/6144/26986/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/9775/6206/6194/2107/2935/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/1981/23708/140801/6161/51121/4686/6132/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/5976/6217/6181/6187/6124/6168/6207/22916/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/6233/6165/6125/6230/6130 93 Potato_virus_Y R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 93/350 115/10654 3.0472739947783268e-121 1.799923172915732e-119 1.114126141248778e-119 6142/6158/6167/7311/6204/6223/25873/6224/6146/51065/6154/6138/6141/6144/26986/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/9775/6206/6194/2107/2935/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/1981/23708/140801/6161/51121/4686/6132/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/5976/6217/6181/6187/6124/6168/6207/22916/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/6233/6165/6125/6230/6130 93 Potato_virus_Y R-HSA-2408557 Selenocysteine synthesis 84/350 93/10654 5.0137438025871065e-118 2.77636063068261e-116 1.718526658649923e-116 6142/6158/6167/7311/6204/6223/25873/6224/6146/51065/6154/6138/6141/6144/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/140801/6161/51121/6132/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/6181/6187/6124/6168/6207/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/6233/6165/6125/6230/6130 84 Potato_virus_Y R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 84/350 112/10654 6.307334763916358e-104 3.2872344710764076e-102 2.034750100309859e-102 6142/6158/6167/7311/6204/6223/25873/6224/6146/51065/6154/6138/6141/6144/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/140801/6161/51121/6132/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/6181/6187/6124/6168/6207/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/6233/6165/6125/6230/6130 84 Potato_virus_Y R-HSA-72766 Translation 118/350 291/10654 6.968977008325622e-103 3.430285349653612e-101 2.123296503706228e-101 6142/6158/1937/6167/7458/7311/6204/8669/6223/25873/51081/8664/6224/6146/51065/6154/3646/8662/6138/6141/10480/6144/26986/8663/6202/6228/23521/6123/6203/51386/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/26589/2107/8894/2935/6134/1965/6169/6160/6234/27335/6191/8665/6166/6128/6135/6201/6164/1978/1981/23708/140801/6161/51121/6132/6156/6155/1938/6159/6147/8661/6175/8666/6235/6129/6218/6143/1973/9045/6217/6181/6187/6124/9669/6168/6207/6208/6222/6157/6137/1983/6176/6170/6209/1977/6139/6152/1974/200916/6136/1964/6193/6122/6173/6133/6210/6231/6229/11224/6205/8668/6233/1975/6165/1968/8667/6125/6230/6130 118 Potato_virus_Y R-HSA-2408522 Selenoamino acid metabolism 84/350 118/10654 1.3280755948921333e-100 6.193026195128579e-99 3.833392714342391e-99 6142/6158/6167/7311/6204/6223/25873/6224/6146/51065/6154/6138/6141/6144/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/140801/6161/51121/6132/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/6181/6187/6124/6168/6207/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/6233/6165/6125/6230/6130 84 Potato_virus_Y R-HSA-9010553 Regulation of expression of SLITs and ROBOs 94/350 171/10654 6.788808783732183e-97 3.007442291193357e-95 1.8615628296444568e-95 6142/6158/6167/7311/6204/6223/25873/6224/6146/51065/6154/6138/6141/6144/26986/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/9775/6206/6194/2107/2935/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/1981/23708/140801/6161/51121/4686/6132/6156/7316/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/6181/6187/6124/6168/6207/22916/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/5704/6233/6165/6125/6230/6130 94 Potato_virus_Y R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 91/350 185/10654 1.0682650807434359e-87 4.507061245422306e-86 2.7898050479565422e-86 6142/6158/6167/7311/6204/6223/25873/83732/6224/6146/51065/6154/6138/6141/51602/6144/6202/6228/23521/6123/6203/116832/6227/23246/9349/4736/3921/6188/6189/6232/6206/6194/6134/6169/6160/6234/9790/6191/6166/6128/6135/6201/55781/6164/140801/6161/51121/6132/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/6181/6187/4691/6124/6168/6207/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/10528/6233/6165/6125/6230/6130 91 Potato_virus_Y R-HSA-8868773 rRNA processing in the nucleus and cytosol 92/350 195/10654 1.5874810281645463e-86 6.393219049789946e-85 3.9573091659030083e-085 6142/6158/6167/7311/6204/6223/25873/83732/6224/6146/51065/6154/6138/6141/51602/6144/1736/6202/6228/23521/6123/6203/116832/6227/23246/9349/4736/3921/6188/6189/6232/6206/6194/6134/6169/6160/6234/9790/6191/6166/6128/6135/6201/55781/6164/140801/6161/51121/6132/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/6181/6187/4691/6124/6168/6207/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/10528/6233/6165/6125/6230/6130 92 Potato_virus_Y R-HSA-5663205 Infectious disease 118/350 383/10654 2.0132115693808466e-86 7.755241089006217e-85 4.8003809045648564e-85 6142/6158/6167/1025/23165/7311/6204/6223/25873/9883/9972/6224/6146/348995/51065/6154/6138/6141/9636/6144/6202/6228/79023/23521/6123/6203/57122/23636/116832/5903/6227/9349/4736/23225/3921/6188/6189/6232/8021/6206/6194/6134/6169/10762/6160/6234/6191/55706/7175/6166/6128/6135/6201/129401/23511/6164/140801/6161/51121/4686/6132/9631/6156/7316/6155/1938/6159/6147/6175/6235/6129/6218/6143/9045/6217/53371/6181/6187/6124/55746/6168/6207/22916/6208/6222/8086/6157/6137/6176/6170/6209/6139/6152/200916/6136/8480/6193/6122/6173/6133/23279/6210/4927/5609/6231/6229/9688/11224/6205/5704/6233/6165/8731/6125/4869/79902/6230/6130 118 Potato_virus_Y R-HSA-376176 Signaling by ROBO receptors 95/350 218/10654 2.591161773507051e-85 9.565705547196863e-84 5.921031947356026e-84 6142/6158/6167/7311/6204/6223/25873/6224/6146/51065/6154/6138/6141/6144/26986/6202/6228/23521/6123/6203/116832/6227/9349/1630/4736/3921/6188/6189/6232/9775/6206/6194/2107/2935/6134/6169/6160/6234/6191/6166/6128/6135/6201/6164/1981/23708/140801/6161/51121/4686/6132/6156/7316/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/6181/6187/6124/6168/6207/22916/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/5704/6233/6165/6125/6230/6130 95 Potato_virus_Y R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 57/350 59/10654 4.184738756671067e-84 1.4830714153642263e-82 9.179995335686848e-83 7458/6204/8669/6223/8664/6224/51065/3646/8662/10480/26986/8663/6202/6228/6203/51386/6227/3921/6188/6189/6232/6206/6194/8894/1965/6234/27335/6191/8665/6201/1978/1981/8661/8666/6235/6218/1973/6217/6187/6207/6208/6222/6209/1977/1974/1964/6193/6210/6231/6229/6205/8668/6233/1975/1968/8667/6230 57 Potato_virus_Y R-HSA-72312 rRNA processing 92/350 205/10654 5.772171358255257e-84 1.96697839362083e-82 1.2175308816400768e-82 6142/6158/6167/7311/6204/6223/25873/83732/6224/6146/51065/6154/6138/6141/51602/6144/1736/6202/6228/23521/6123/6203/116832/6227/23246/9349/4736/3921/6188/6189/6232/6206/6194/6134/6169/6160/6234/9790/6191/6166/6128/6135/6201/55781/6164/140801/6161/51121/6132/6156/6155/6159/6147/6175/6235/6129/6218/6143/9045/6217/6181/6187/4691/6124/6168/6207/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/10528/6233/6165/6125/6230/6130 92 Potato_virus_Y R-HSA-72649 Translation initiation complex formation 56/350 58/10654 1.4571181399823096e-82 4.610738114372593e-81 2.853979514777381e-81 7458/6204/8669/6223/8664/6224/51065/3646/8662/10480/26986/8663/6202/6228/6203/51386/6227/3921/6188/6189/6232/6206/6194/8894/1965/6234/27335/6191/8665/6201/1981/8661/8666/6235/6218/1973/6217/6187/6207/6208/6222/6209/1977/1974/1964/6193/6210/6231/6229/6205/8668/6233/1975/1968/8667/6230 56 Potato_virus_Y R-HSA-72702 Ribosomal scanning and start codon recognition 56/350 58/10654 1.4571181399823096e-82 4.610738114372593e-81 2.853979514777381e-81 7458/6204/8669/6223/8664/6224/51065/3646/8662/10480/8663/6202/6228/6203/51386/6227/3921/6188/6189/6232/6206/6194/8894/1965/6234/27335/6191/8665/6201/1981/8661/8666/6235/6218/1973/6217/6187/6207/6208/6222/1983/6209/1977/1974/1964/6193/6210/6231/6229/6205/8668/6233/1975/1968/8667/6230 56 Potato_virus_Y R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 49/350 51/10654 8.100286815995786e-72 2.4747772824042296e-70 1.531850973188314e-70 6204/8669/6223/8664/6224/51065/3646/8662/10480/8663/6202/6228/6203/51386/6227/3921/6188/6189/6232/6206/6194/8894/1965/6234/27335/6191/8665/6201/8661/8666/6235/6218/6217/6187/6207/6208/6222/6209/1964/6193/6210/6231/6229/6205/8668/6233/1968/8667/6230 49 Potato_virus_Y R-HSA-71291 Metabolism of amino acids and derivatives 89/350 372/10654 1.9940198018076117e-53 5.889005148005147e-52 3.6452081289184765e-52 6142/6158/6167/7311/6204/6223/25873/6224/6146/51065/6154/6138/1738/6141/6144/6202/6228/23521/6123/6203/116832/6227/9349/4736/3921/6188/6189/6232/6206/6194/6134/6169/6160/6234/6191/445/6166/6999/6128/6135/6201/6164/140801/6161/51121/6132/6156/6155/6159/6147/6175/6235/6129/6218/6143/5160/9045/6217/6181/6187/6124/6168/6207/6208/6222/6157/6137/6176/6170/6209/6139/6152/200916/6136/6193/6122/6173/6133/6210/6231/6229/11224/6205/5704/6233/6165/6125/6230/6130 89 Potato_virus_Y R-HSA-1169408 ISG15 antiviral mechanism 42/350 72/10654 2.8690038314184434e-44 8.199798047215293e-43 5.075555165259793e-43 8672/23165/7311/9883/9972/348995/9636/317649/79023/57122/23636/5903/25820/1982/23225/7706/8021/9775/10762/55706/7175/129401/9470/23511/1981/9631/7316/1973/53371/55746/8086/9246/1977/1974/8480/51191/23279/4927/9688/6233/5595/79902 42 Potato_virus_Y R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 43/350 80/10654 3.5747141468799823e-43 9.897489794173951e-42 6.126401547777866e-42 8672/23165/7311/9883/9972/348995/9636/317649/79023/6059/57122/23636/5903/25820/1982/23225/7706/8021/9775/10762/55706/7175/129401/9470/23511/1981/9631/7316/1973/53371/55746/8086/9246/1977/1974/8480/51191/23279/4927/9688/6233/5595/79902 43 Potato_virus_Y R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 30/350 35/10654 2.5465479550304364e-40 6.837095418657475e-39 4.232062151741173e-39 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10189/10762/55706/7175/129401/23511/4686/9631/7884/10482/53371/55746/22916/8086/1977/8480/23279/4927/9688/79902 30 Potato_virus_Y R-HSA-159227 Transport of the SLBP independent Mature mRNA 29/350 34/10654 7.222779122669575e-39 1.88217126549566e-37 1.1650365086411298e-37 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10189/10762/55706/7175/129401/23511/4686/9631/10482/53371/55746/22916/8086/1977/8480/23279/4927/9688/79902 29 Potato_virus_Y R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 30/350 42/10654 7.051259682136334e-36 1.7849760223922264e-34 1.1048740735016633e-34 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10189/10762/55706/7175/129401/23511/4686/9631/7884/10482/53371/55746/22916/8086/1977/8480/23279/4927/9688/79902 30 Potato_virus_Y R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 29/350 41/10654 1.6659603178339423e-34 4.1001134488913135e-33 2.5379103087470295e-33 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10189/10762/55706/7175/129401/23511/4686/9631/10482/53371/55746/22916/8086/1977/8480/23279/4927/9688/79902 29 Potato_virus_Y R-HSA-166208 mTORC1-mediated signalling 22/350 23/10654 2.689485444592673e-32 6.440227307862455e-31 3.98640659070493e-31 2475/55004/58528/10325/10670/6194/6198/8649/153129/1978/1981/6009/389541/64121/57521/1977/7529/10542/84335/1975/28956/64223 22 Potato_virus_Y R-HSA-180746 Nuclear import of Rev protein 25/350 33/10654 3.834327734368872e-31 8.940037822765317e-30 5.533752768992195e-30 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/4869/79902 25 Potato_virus_Y R-HSA-3232142 SUMOylation of ubiquitinylation proteins 26/350 38/10654 2.0300057186391445e-30 4.611756581318672e-29 2.8546099309338583e-29 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/5987/5371/8480/23279/4927/9688/79902 26 Potato_virus_Y R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 24/350 31/10654 2.4389862604418957e-30 5.025446108724464e-29 3.1106777030360535e-29 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Potato_virus_Y R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 24/350 31/10654 2.4389862604418957e-30 5.025446108724464e-29 3.1106777030360535e-29 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Potato_virus_Y R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 24/350 31/10654 2.4389862604418957e-30 5.025446108724464e-29 3.1106777030360535e-29 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Potato_virus_Y R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 24/350 31/10654 2.4389862604418957e-30 5.025446108724464e-29 3.1106777030360535e-29 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Potato_virus_Y R-HSA-429947 Deadenylation of mRNA 22/350 25/10654 2.5330921366394993e-30 5.100726438778628e-29 3.1572751272468404e-29 55571/4850/255967/26986/4848/9924/23019/10605/9775/9337/57472/1981/85456/29883/1973/5073/1977/1974/25904/1975/246175/4849 22 Potato_virus_Y R-HSA-177243 Interactions of Rev with host cellular proteins 25/350 36/10654 1.5170760991816397e-29 2.9869542752776285e-28 1.8488810471897878e-28 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/4869/79902 25 Potato_virus_Y R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 24/350 33/10654 3.3695841119182024e-29 6.352024517360696e-28 3.931810352316649e-28 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Potato_virus_Y R-HSA-180910 Vpr-mediated nuclear import of PICs 24/350 33/10654 3.3695841119182024e-29 6.352024517360696e-28 3.931810352316649e-28 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Potato_virus_Y R-HSA-165054 Rev-mediated nuclear export of HIV RNA 24/350 34/10654 1.1119164993254088e-28 2.010526568167984e-27 1.2444865653029819e-27 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Potato_virus_Y R-HSA-4085377 SUMOylation of SUMOylation proteins 24/350 34/10654 1.1119164993254088e-28 2.010526568167984e-27 1.2444865653029819e-27 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Potato_virus_Y R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 24/350 35/10654 3.4337126901694006e-28 6.084538886980177e-27 3.7662406559542275e-27 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Potato_virus_Y R-HSA-165159 mTOR signalling 25/350 40/10654 9.013711954395606e-28 1.5357978445374053e-26 9.506364227206702e-27 2475/51422/7249/55004/58528/10325/10670/6194/6198/8649/153129/1978/1981/6009/389541/64121/57521/207/1977/7529/10542/84335/1975/28956/64223 25 Potato_virus_Y R-HSA-168276 NS1 Mediated Effects on Host Pathways 25/350 40/10654 9.013711954395606e-28 1.5357978445374053e-26 9.506364227206702e-27 23165/9883/9972/348995/9636/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 25 Potato_virus_Y R-HSA-176033 Interactions of Vpr with host cellular proteins 24/350 36/10654 9.997722850671899e-28 1.6713174425840193e-26 1.0345210735253346e-26 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Potato_virus_Y R-HSA-913531 Interferon Signaling 47/350 199/10654 1.2545972384313773e-27 2.0584688023151858e-26 1.2741621076466815e-26 8672/23165/7311/9883/9972/348995/9636/317649/79023/6059/3383/57122/23636/5903/25820/1982/23225/7706/8021/9775/10762/55706/7175/129401/9470/23511/1981/9631/7316/1973/53371/7412/55746/8086/10346/9246/1977/5371/1974/8480/51191/23279/4927/9688/6233/5595/79902 47 Potato_virus_Y R-HSA-72202 Transport of Mature Transcript to Cytoplasm 33/350 84/10654 1.3499179140642462e-27 2.174595039747131e-26 1.346042551631526e-26 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/9775/10189/10762/55706/7175/129401/23511/4686/9631/7884/10482/53371/11338/55746/22916/8086/1977/6428/8480/23279/4927/9688/79902 33 Potato_virus_Y R-HSA-168253 Host Interactions with Influenza Factors 25/350 42/10654 5.375632459193384e-27 8.505018497938103e-26 5.264482163984499e-26 23165/9883/9972/348995/9636/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 25 Potato_virus_Y R-HSA-4570464 SUMOylation of RNA binding proteins 26/350 47/10654 7.195880728851846e-27 1.1185176010110062e-25 6.92346049811969e-26 23165/9883/9972/348995/51602/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/6045/8480/23279/4927/9688/79902 26 Potato_virus_Y R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 31/350 75/10654 8.467670165112472e-27 1.293509614877526e-25 8.006635491875858e-26 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/9775/10189/10762/55706/7175/129401/23511/4686/9631/10482/53371/11338/55746/22916/8086/6428/8480/23279/4927/9688/79902 31 Potato_virus_Y R-HSA-191859 snRNP Assembly 27/350 53/10654 1.4674475331287194e-26 2.166930857253409e-25 1.341298534666777e-25 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/4686/9631/53371/55746/22916/8086/8480/25929/23279/4927/9688/79902 27 Potato_virus_Y R-HSA-194441 Metabolism of non-coding RNA 27/350 53/10654 1.4674475331287194e-26 2.166930857253409e-25 1.341298534666777e-25 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/4686/9631/53371/55746/22916/8086/8480/25929/23279/4927/9688/79902 27 Potato_virus_Y R-HSA-429914 Deadenylation-dependent mRNA decay 27/350 56/10654 1.0180667720061397e-25 1.478700262290885e-24 9.152938536931818e-25 55571/4850/255967/1656/26986/4848/9924/23019/10605/80153/9775/54464/9337/57472/1981/85456/29883/1973/5073/27257/1977/1974/167227/25904/1975/246175/4849 27 Potato_virus_Y R-HSA-168325 Viral Messenger RNA Synthesis 24/350 43/10654 5.186224569102143e-25 7.411282206813707e-24 4.587475382856055e-24 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Potato_virus_Y R-HSA-4615885 SUMOylation of DNA replication proteins 24/350 45/10654 2.3029792688292234e-24 3.2387930669566536e-023 2.0047655790476615e-23 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Potato_virus_Y R-HSA-3371556 Cellular response to heat stress 31/350 89/10654 4.209363103750049e-24 5.827337046753974e-23 3.6070364754173943e-23 2475/23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/3313/10762/55706/7175/129401/23511/9631/53371/57521/55746/8086/8480/5594/23279/4927/9688/84335/5595/79902/64223 31 Potato_virus_Y R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 29/350 77/10654 9.58058349744531e-24 1.30590722749793e-22 8.083374902297987e-23 672/23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/5885/23511/9631/53371/55746/8086/6045/5371/8480/8924/23279/4927/9688/79902 29 Potato_virus_Y R-HSA-3371453 Regulation of HSF1-mediated heat shock response 27/350 69/10654 1.0467102799475839e-22 1.405129254596302e-21 8.697544750441648e-22 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/3313/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/5594/23279/4927/9688/5595/79902 27 Potato_virus_Y R-HSA-2980766 Nuclear Envelope Breakdown 24/350 52/10654 2.110538271848821e-22 2.7909506102359036e-21 1.727557642785916e-21 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Potato_virus_Y R-HSA-2262752 Cellular responses to stress 63/350 479/10654 5.985089586851012e-22 7.798219667573525e-21 4.826984016639904e-21 2475/55004/58528/1017/23165/7311/9883/9972/1432/348995/538/84617/10325/79023/57122/23636/5903/10670/23225/192670/8021/8649/3313/153129/1780/8726/55662/10762/55706/7175/129401/23511/5600/1781/9631/7316/6009/26523/53371/192669/389541/64121/57521/55746/8086/6045/8480/9114/5594/23279/4927/5609/9688/10542/5704/84335/6233/28956/5595/6647/8994/79902/64223 63 Potato_virus_Y R-HSA-8953897 Cellular responses to external stimuli 63/350 493/10654 2.817037147133773e-21 3.617239003421048e-20 2.239018083381687e-20 2475/55004/58528/1017/23165/7311/9883/9972/1432/348995/538/84617/10325/79023/57122/23636/5903/10670/23225/192670/8021/8649/3313/153129/1780/8726/55662/10762/55706/7175/129401/23511/5600/1781/9631/7316/6009/26523/53371/192669/389541/64121/57521/55746/8086/6045/8480/9114/5594/23279/4927/5609/9688/10542/5704/84335/6233/28956/5595/6647/8994/79902/64223 63 Potato_virus_Y R-HSA-3700989 Transcriptional Regulation by TP53 54/350 365/10654 3.0382013202012858e-21 3.84549481385477e-20 2.3803050944734885e-20 2475/51422/7249/55004/672/55571/58528/1025/4850/1017/7311/834/27161/1432/839/11200/4848/10325/10670/23019/843/192670/7534/8649/153129/9337/5600/57472/10128/7316/5728/85456/6009/29883/26523/192669/389541/64121/1107/57521/207/5371/7529/25904/835/1108/10542/6233/253260/28956/246175/4849/4869/64223 54 Potato_virus_Y R-HSA-6784531 tRNA processing in the nucleus 24/350 57/10654 3.2060754301934116e-21 4.0008208889455815e-20 2.476449665130864e-20 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Potato_virus_Y R-HSA-4551638 SUMOylation of chromatin organization proteins 26/350 71/10654 4.938095387603521e-21 6.076600713078778e-20 3.7613270423120394e-20 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/1107/55746/8086/6045/8480/23279/4927/9688/79902 26 Potato_virus_Y R-HSA-6807070 PTEN Regulation 34/350 140/10654 1.2911700396900754e-20 1.5670913084457627e-19 9.700066195797107e-20 2475/55004/58528/7311/27161/10325/10670/192670/8649/153129/8726/7316/5728/6009/26523/192669/389541/64121/1107/57521/10273/207/6045/5987/5371/5594/1108/10542/5704/6233/28956/5595/11060/64223 34 Potato_virus_Y R-HSA-70171 Glycolysis 25/350 71/10654 8.842057183127765e-20 1.0586571167907027e-18 6.552932848377761e-19 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/5528/9631/53371/55746/8086/8480/23279/4927/9688/79902 25 Potato_virus_Y R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 42/350 244/10654 3.715400132870558e-19 4.389126023631085e-18 2.716804869088507e-18 23165/3178/9883/9972/348995/79023/57122/23636/5903/23225/8021/9775/10189/10762/55706/7175/129401/23511/10594/4686/9631/7884/10482/53371/11051/11338/9343/3185/55746/22916/8086/56339/5725/1977/6428/8480/24144/23279/4927/9688/1994/79902 42 Potato_virus_Y R-HSA-1257604 PIP3 activates AKT signaling 43/350 264/10654 1.2000108452684964e-18 1.398960011720905e-17 8.659358038571839e-18 2475/7249/55004/58528/7311/27161/10325/2064/10670/192670/8649/153129/3667/8726/5528/2100/7316/5728/6009/26523/842/3630/192669/389541/64121/1107/57521/10273/207/6045/5987/5371/5594/1108/10542/5704/84335/6233/253260/28956/5595/11060/64223 43 Potato_virus_Y R-HSA-162909 Host Interactions of HIV factors 30/350 129/10654 9.690411910718287e-18 1.115026617259273e-16 6.901851818843785e-17 1025/23165/7311/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/7316/53371/55746/8086/8480/23279/4927/9688/5704/6233/4869/79902 30 Potato_virus_Y R-HSA-162599 Late Phase of HIV Life Cycle 31/350 139/10654 9.869817353147297e-18 1.1211100224216032e-16 6.939507207813419e-17 1025/23165/7311/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/4686/9631/7316/53371/55746/22916/8086/8480/23279/4927/9688/6233/8731/79902 31 Potato_virus_Y R-HSA-5628897 TP53 Regulates Metabolic Genes 25/350 86/10654 1.7434447850427823e-17 1.9553064298074747e-16 1.210306106605316e-16 2475/51422/7249/55004/58528/27161/10325/10670/192670/7534/8649/153129/10128/5728/6009/26523/192669/389541/64121/57521/207/7529/10542/28956/64223 25 Potato_virus_Y R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK 16/350 29/10654 6.03864753015824e-17 6.68780213965025e-16 4.1396517937005836e-16 2475/51422/7249/55004/58528/10325/10670/8649/153129/6009/389541/64121/57521/10542/28956/64223 16 Potato_virus_Y R-HSA-70326 Glucose metabolism 25/350 91/10654 7.811587860856366e-17 8.54452696878857e-16 5.288937330092485e-16 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/5528/9631/53371/55746/8086/8480/23279/4927/9688/79902 25 Potato_virus_Y R-HSA-162587 HIV Life Cycle 31/350 152/10654 1.496752460293712e-16 1.6172227802685718e-15 1.0010372680526624e-15 1025/23165/7311/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/4686/9631/7316/53371/55746/22916/8086/8480/23279/4927/9688/6233/8731/79902 31 Potato_virus_Y R-HSA-9006925 Intracellular signaling by second messengers 43/350 305/10654 3.000814408484016e-16 3.2032789950805278e-15 1.9827828875335097e-15 2475/7249/55004/58528/7311/27161/10325/2064/10670/192670/8649/153129/3667/8726/5528/2100/7316/5728/6009/26523/842/3630/192669/389541/64121/1107/57521/10273/207/6045/5987/5371/5594/1108/10542/5704/84335/6233/253260/28956/5595/11060/64223 43 Potato_virus_Y R-HSA-5578749 Transcriptional regulation by small RNAs 26/350 106/10654 3.9088634383110086e-16 4.122920245647088e-15 2.5520273826566866e-15 23165/9883/27161/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/26523/53371/55746/8086/8480/23279/4927/9688/79902 26 Potato_virus_Y R-HSA-211000 Gene Silencing by RNA 29/350 136/10654 4.220436599806655e-16 4.3991845028572895e-15 2.7230309207421274e-15 23165/9883/27161/9972/348995/79023/57122/23636/5903/23225/192670/8021/10762/55706/7175/129401/23511/9631/26523/53371/192669/55746/23405/8086/8480/23279/4927/9688/79902 29 Potato_virus_Y R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 33/350 182/10654 6.04451870413783e-16 6.227259967286184e-15 3.854582919040159e-15 672/23165/9883/9972/348995/51602/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/5885/23511/9631/53371/1107/55746/8086/6045/5987/5371/8480/8924/23279/4927/9688/4869/79902 33 Potato_virus_Y R-HSA-2990846 SUMOylation 33/350 188/10654 1.6388069694606537e-15 1.6689459482093554e-14 1.0330531531627353e-14 672/23165/9883/9972/348995/51602/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/5885/23511/9631/53371/1107/55746/8086/6045/5987/5371/8480/8924/23279/4927/9688/4869/79902 33 Potato_virus_Y R-HSA-8943724 Regulation of PTEN gene transcription 20/350 61/10654 2.2864531314738006e-15 2.30204258464294e-14 1.424930719495036e-14 2475/55004/58528/10325/10670/8649/153129/8726/6009/389541/64121/1107/57521/6045/5594/1108/10542/28956/5595/64223 20 Potato_virus_Y R-HSA-5619102 SLC transporter disorders 24/350 99/10654 7.34666502306658e-15 7.313646303861786e-14 4.5270401857098613e-14 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Potato_virus_Y R-HSA-72306 tRNA processing 24/350 107/10654 4.7768126450752235e-14 4.702506670596276e-13 2.9107829100399905e-13 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Potato_virus_Y R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 12/350 21/10654 2.9548145163321814e-13 2.8768853422750685e-12 1.7807499861296318e-12 55571/4850/4848/23019/9337/57472/85456/29883/25904/246175/4849/4869 12 Potato_virus_Y R-HSA-5619115 Disorders of transmembrane transporters 29/350 176/10654 4.913264656026555e-13 4.731687483956008e-12 2.9288454070821917e-12 1080/23165/7311/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/7316/53371/55746/8086/8480/23279/4927/9688/5704/6233/79902 29 Potato_virus_Y R-HSA-68875 Mitotic Prophase 26/350 142/10654 6.601195537079683e-13 6.288880909518924e-12 3.8927253817979806e-12 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/5594/23279/4927/9688/5595/79902 26 Potato_virus_Y R-HSA-162906 HIV Infection 33/350 233/10654 9.389297821328638e-13 8.849912627337418e-12 5.47796659004728e-12 1025/23165/7311/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/4686/9631/7316/53371/55746/22916/8086/8480/23279/4927/9688/5704/6233/8731/4869/79902 33 Potato_virus_Y R-HSA-1632852 Macroautophagy 21/350 95/10654 2.5841886589366753e-12 2.410095949281994e-11 1.491814173192253e-11 2475/51422/7249/55004/58528/7311/10325/10670/8649/153129/7316/6009/389541/64121/57521/55054/10542/6233/28956/10452/64223 21 Potato_virus_Y R-HSA-9612973 Autophagy 22/350 119/10654 3.386525139797218e-11 3.125480493604516e-10 1.9346267520113496e-10 2475/51422/7249/55004/58528/1080/7311/10325/10670/8649/153129/7316/6009/389541/64121/57521/55054/10542/6233/28956/10452/64223 22 Potato_virus_Y R-HSA-9639288 Amino acids regulate mTORC1 15/350 55/10654 1.49921614997322e-10 1.3693871225528586e-9 8.47630617619151e-10 2475/55004/58528/10325/10670/8649/153129/6009/389541/64121/57521/9114/10542/28956/64223 15 Potato_virus_Y R-HSA-168638 NOD1/2 Signaling Pathway 12/350 36/10654 8.058348013162295e-10 7.285404428226319e-9 4.50955887739802e-9 7311/834/1432/329/837/841/5600/7316/1540/842/835/6233 12 Potato_virus_Y R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 13/350 49/10654 3.746943118570076e-9 3.353324851568775e-8 2.0756590800372248e-8 55571/4850/1017/4848/23019/9337/57472/85456/29883/25904/246175/4849/4869 13 Potato_virus_Y R-HSA-68886 M Phase 37/350 395/10654 7.568922409035497e-9 6.70606525440545e-8 4.1509563948499946e-8 23165/7311/9883/9972/348995/84617/79023/57122/23636/5903/23225/6232/8021/54908/1780/10762/55706/7175/129401/5885/23511/5528/1781/9631/7316/53371/55746/8086/8480/5594/23279/4927/9688/5704/6233/5595/79902 37 Potato_virus_Y R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 13/350 55/10654 1.7321023955877807e-8 1.519448240089875e-7 9.405162564890398e-8 7311/834/1432/329/837/351/841/5600/7316/1540/842/835/6233 13 Potato_virus_Y R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 16/350 88/10654 2.1992166301020735e-8 1.910299935559252e-7 1.1824477443582874e-7 7311/1432/26986/8021/7534/54464/5600/1981/7316/5073/207/167227/7529/5704/6233/1994 16 Potato_virus_Y R-HSA-71387 Metabolism of carbohydrates 28/350 295/10654 4.248570159116953e-7 3.65459530192002e-6 2.262141086254402e-6 23165/7311/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/5528/9631/7316/53371/55746/8086/8480/23279/4927/9688/6233/79902 28 Potato_virus_Y R-HSA-8934593 Regulation of RUNX1 Expression and Activity 7/350 17/10654 5.694233235532646e-7 4.85104869873262e-6 3.002728254769746e-6 27161/192670/595/26523/192669/861/5371 7 Potato_virus_Y R-HSA-6804757 Regulation of TP53 Degradation 9/350 36/10654 1.7266870024248313e-6 1.456994937284191e-5 9.018585747000875e-6 2475/1017/7311/11200/7316/207/6233/253260/64223 9 Potato_virus_Y R-HSA-6806003 Regulation of TP53 Expression and Degradation 9/350 37/10654 2.216327580027196e-6 1.8525153168906564e-5 1.1466799098253913e-5 2475/1017/7311/11200/7316/207/6233/253260/64223 9 Potato_virus_Y R-HSA-5654738 Signaling by FGFR2 12/350 73/10654 3.9566404151129376e-6 3.276246175504732e-5 2.0279485059260607e-5 8569/7311/3178/3845/4686/7316/3185/22916/5725/5594/6233/5595 12 Potato_virus_Y R-HSA-5675221 Negative regulation of MAPK pathway 9/350 40/10654 4.4648928725120685e-6 3.662865819486753e-5 2.2672604157687995e-5 7311/3845/5528/80824/7316/7529/5594/6233/5595 9 Potato_virus_Y R-HSA-1295596 Spry regulation of FGF signaling 6/350 16/10654 7.2960572484835095e-6 5.9305566258315495e-5 3.6709278864895304e-5 8569/7311/7316/5594/6233/5595 6 Potato_virus_Y R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 12/350 78/10654 8.063474589928778e-6 6.494762260615362e-5 4.020162929524301e-5 7311/9636/351/843/841/7706/7316/1540/9246/51191/6233/79132 12 Potato_virus_Y R-HSA-2559585 Oncogene Induced Senescence 8/350 33/10654 8.466470694529031e-6 6.75792165347092e-5 4.183054748079304e-5 7311/192670/7316/26523/192669/5594/6233/5595 8 Potato_virus_Y R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 8/350 34/10654 1.0757810524977334e-5 8.510196540294569e-5 5.2676872965349546e-5 7311/9636/7706/7316/1540/9246/51191/6233 8 Potato_virus_Y R-HSA-450604 KSRP (KHSRP) binds and destabilizes mRNA 6/350 17/10654 1.0965130298445477e-5 8.597438446391764e-5 5.321688761518486e-5 1432/7534/5600/5073/207/167227 6 Potato_virus_Y R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 7/350 25/10654 1.1210511967764291e-5 8.712731231086984e-5 5.3930533104387776e-5 2475/7249/842/207/84335/253260/64223 7 Potato_virus_Y R-HSA-109581 Apoptosis 18/350 178/10654 2.1994584768741723e-5 1.6945393134874058e-4 1.0488950722667679e-4 7311/839/329/840/841/1630/836/7534/7316/842/207/5339/7529/5594/10059/5704/6233/5595 18 Potato_virus_Y R-HSA-264870 Caspase-mediated cleavage of cytoskeletal proteins 5/350 12/10654 2.4345946881706257e-5 1.8595266325165298e-4 1.1510198117394702e-4 839/840/841/836/5339 5 Potato_virus_Y R-HSA-190236 Signaling by FGFR 12/350 87/10654 2.5251714432872944e-5 1.9122238450876435e-4 1.1836386162417277e-4 8569/7311/3178/3845/4686/7316/3185/22916/5725/5594/6233/5595 12 Potato_virus_Y R-HSA-5357801 Programmed Cell Death 18/350 181/10654 2.758172628313513e-5 2.070966905665909e-4 1.2818982509824625e-4 7311/839/329/840/841/1630/836/7534/7316/842/207/5339/7529/5594/10059/5704/6233/5595 18 Potato_virus_Y R-HSA-5674135 MAP2K and MAPK activation 8/350 40/10654 3.8356357682338395e-5 2.819054705026214e-4 1.7449536667680376e-4 8649/2335/3845/1445/7529/5594/28956/5595 8 Potato_virus_Y R-HSA-111461 Cytochrome c-mediated apoptotic response 5/350 13/10654 3.849950556525642e-5 2.819054705026214e-4 1.7449536667680376e-4 840/836/842/5594/5595 5 Potato_virus_Y R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 5/350 13/10654 3.849950556525642e-5 2.819054705026214e-4 1.7449536667680376e-4 7311/2064/7316/207/6233 5 Potato_virus_Y R-HSA-109606 Intrinsic Pathway for Apoptosis 9/350 53/10654 4.96425055524095e-5 3.6051852392979364e-4 2.231556979534543e-4 840/841/836/7534/842/207/7529/5594/5595 9 Potato_virus_Y R-HSA-2467813 Separation of Sister Chromatids 18/350 190/10654 5.268300346789886e-5 3.794889518094178e-4 2.3489811559071721e-4 7311/348995/84617/79023/57122/5903/6232/54908/1780/5885/5528/1781/7316/55746/23279/5704/6233/79902 18 Potato_virus_Y R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 12/350 94/10654 5.5317994530962486e-5 3.952559931809094e-4 2.446576837914385e-4 7311/1432/329/351/841/5600/5528/7316/5594/5609/6233/5595 12 Potato_virus_Y R-HSA-2173789 TGF-beta receptor signaling activates SMADs 7/350 32/10654 6.436755107433291e-5 4.548654745231886e-4 2.815550816521104e-4 57154/7048/7311/7316/9040/10273/6233 7 Potato_virus_Y R-HSA-2500257 Resolution of Sister Chromatid Cohesion 14/350 126/10654 6.468741511277851e-5 4.548654745231886e-4 2.815550816521104e-4 348995/84617/79023/57122/5903/6232/54908/1780/5885/5528/1781/55746/23279/79902 14 Potato_virus_Y R-HSA-141424 Amplification of signal from the kinetochores 12/350 96/10654 6.822339712092001e-5 4.722338269463682e-4 2.9230583799341557e-4 348995/79023/57122/5903/6232/54908/1780/5528/1781/55746/23279/79902 12 Potato_virus_Y R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 12/350 96/10654 6.822339712092001e-5 4.722338269463682e-4 2.9230583799341557e-4 348995/79023/57122/5903/6232/54908/1780/5528/1781/55746/23279/79902 12 Potato_virus_Y R-HSA-5633007 Regulation of TP53 Activity 16/350 160/10654 7.183283211431513e-5 4.933634825835907e-4 3.0538478605922635e-4 2475/51422/672/1017/7311/1432/11200/5600/7316/1107/207/5371/1108/6233/253260/64223 16 Potato_virus_Y R-HSA-430039 mRNA decay by 5' to 3' exoribonuclease 5/350 15/10654 8.50764177847961e-5 5.798285089025334e-4 3.5890537381278354e-4 1656/80153/54464/27257/167227 5 Potato_virus_Y R-HSA-166166 MyD88-independent TLR4 cascade 12/350 99/10654 9.242521937852097e-5 6.203692755255272e-4 3.839995159187355e-4 7311/1432/329/351/841/5600/5528/7316/5594/5609/6233/5595 12 Potato_virus_Y R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 12/350 99/10654 9.242521937852097e-5 6.203692755255272e-4 3.839995159187355e-4 7311/1432/329/351/841/5600/5528/7316/5594/5609/6233/5595 12 Potato_virus_Y R-HSA-187687 Signalling to ERKs 7/350 34/10654 9.721859083270351e-5 6.47636627652446e-4 4.0087760841977474e-4 1432/4914/3845/5600/7529/5594/5595 7 Potato_virus_Y R-HSA-68882 Mitotic Anaphase 18/350 201/10654 1.0945835966524014e-4 7.237321392791252e-4 4.4797961811147e-4 7311/348995/84617/79023/57122/5903/6232/54908/1780/5885/5528/1781/7316/55746/23279/5704/6233/79902 18 Potato_virus_Y R-HSA-2555396 Mitotic Metaphase and Anaphase 18/350 202/10654 1.1663001679007199e-4 7.65438480562991e-4 4.7379523389962975e-4 7311/348995/84617/79023/57122/5903/6232/54908/1780/5885/5528/1781/7316/55746/23279/5704/6233/79902 18 Potato_virus_Y R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 5/350 16/10654 1.2043112711948433e-4 7.845733722636994e-4 4.856394522387875e-4 57154/7048/7311/7316/6233 5 Potato_virus_Y R-HSA-2173788 Downregulation of TGF-beta receptor signaling 6/350 26/10654 1.5875539249174023e-4 0.0010266954580122763 6.355094851186836e-4 57154/7048/7311/7316/10273/6233 6 Potato_virus_Y R-HSA-6790901 rRNA modification in the nucleus and cytosol 9/350 62/10654 1.752098150411484e-4 0.0011248977980178078 6.962952985235571e-4 51602/1736/6203/6194/9790/6201/6187/6208/10528 9 Potato_virus_Y R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 31/350 473/10654 1.8861060083021238e-4 0.0012022229664429365 7.441584478041701e-4 2475/8569/23191/7311/3178/1432/51741/2064/4914/3667/2335/3845/5600/5528/4686/7316/1445/3630/3185/22916/10273/207/5725/7529/9114/5594/6233/253260/5595/5774/64223 31 Potato_virus_Y R-HSA-450341 Activation of the AP-1 family of transcription factors 4/350 10/10654 2.0548281212793827e-4 0.001291189869115981 7.992276604602901e-4 1432/5600/5594/5595 4 Potato_virus_Y R-HSA-74749 Signal attenuation 4/350 10/10654 2.0548281212793827e-4 0.001291189869115981 7.992276604602901e-4 3667/3630/5594/5595 4 Potato_virus_Y R-HSA-111471 Apoptotic factor-mediated response 5/350 18/10654 2.2375237206698925e-4 0.0013814573203082211 8.551018936445091e-4 840/836/842/5594/5595 5 Potato_virus_Y R-HSA-5675482 Regulation of necroptotic cell death 5/350 18/10654 2.2375237206698925e-4 0.0013814573203082211 8.551018936445091e-4 7311/329/841/7316/6233 5 Potato_virus_Y R-HSA-450294 MAP kinase activation 9/350 64/10654 2.2452579472278088e-4 0.0013814573203082211 8.551018936445091e-4 7311/1432/5600/5528/7316/5594/5609/6233/5595 9 Potato_virus_Y R-HSA-2559580 Oxidative Stress Induced Senescence 13/350 125/10654 2.2973744452756416e-4 0.001403775005871875 8.689162148737637e-4 7311/1432/192670/8726/5600/7316/26523/192669/6045/5594/5609/6233/5595 13 Potato_virus_Y R-HSA-69620 Cell Cycle Checkpoints 22/350 293/10654 2.616605202024444e-4 0.0015878850746531901 9.828776569969255e-4 672/1017/7311/348995/11200/79023/57122/5903/6232/7534/54908/1780/5528/1781/7316/55746/8924/7529/23279/5704/6233/79902 22 Potato_virus_Y R-HSA-5683057 MAPK family signaling cascades 22/350 294/10654 2.7447154690523213e-4 0.0016542978949526236 0.0010239862222529606 7311/27161/2064/192670/8649/3667/2335/3845/5528/80824/7316/26523/1445/192669/8556/7529/5594/4609/5704/6233/28956/5595 22 Potato_virus_Y R-HSA-5654741 Signaling by FGFR3 7/350 40/10654 2.8440857185428744e-4 0.0017019541349864854 0.001053484738419816 8569/7311/3845/7316/5594/6233/5595 7 Potato_virus_Y R-HSA-5663202 Diseases of signal transduction 26/350 377/10654 2.8622027777989425e-4 0.0017019541349864854 0.001053484738419816 2475/7249/7048/7311/2064/3667/2335/3845/5528/2100/4686/7316/5728/842/1445/22916/207/7529/5594/4609/5704/84335/6233/253260/5595/64223 26 Potato_virus_Y R-HSA-5654732 Negative regulation of FGFR3 signaling 6/350 29/10654 3.013815318536656e-4 0.001756933436961605 0.0010875161229143358 8569/7311/7316/5594/6233/5595 6 Potato_virus_Y R-HSA-8863795 Downregulation of ERBB2 signaling 6/350 29/10654 3.013815318536656e-4 0.001756933436961605 0.0010875161229143358 7311/2064/7316/10273/207/6233 6 Potato_virus_Y R-HSA-69618 Mitotic Spindle Checkpoint 12/350 112/10654 3.014152171762573e-4 0.001756933436961605 0.0010875161229143358 348995/79023/57122/5903/6232/54908/1780/5528/1781/55746/23279/79902 12 Potato_virus_Y R-HSA-5654743 Signaling by FGFR4 7/350 41/10654 3.334293325652251e-4 0.0019308391415214995 0.0011951612127036964 8569/7311/3845/7316/5594/6233/5595 7 Potato_virus_Y R-HSA-8848021 Signaling by PTK6 8/350 54/10654 3.4767622692193876e-4 0.0019873621745344367 0.0012301481441516478 1017/7311/2064/3845/7316/595/207/6233 8 Potato_virus_Y R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 8/350 54/10654 3.4767622692193876e-4 0.0019873621745344367 0.0012301481441516478 1017/7311/2064/3845/7316/595/207/6233 8 Potato_virus_Y R-HSA-5213460 RIPK1-mediated regulated necrosis 5/350 20/10654 3.8353159924789696e-4 0.002164388515500871 0.0013397248622739146 7311/329/841/7316/6233 5 Potato_virus_Y R-HSA-5218859 Regulated Necrosis 5/350 20/10654 3.8353159924789696e-4 0.002164388515500871 0.0013397248622739146 7311/329/841/7316/6233 5 Potato_virus_Y R-HSA-8948751 Regulation of PTEN stability and activity 9/350 69/10654 4.0002832396012606e-4 0.0022431968039789345 0.0013885060411940422 7311/7316/5728/10273/207/5987/5704/6233/11060 9 Potato_virus_Y R-HSA-5654733 Negative regulation of FGFR4 signaling 6/350 31/10654 4.4195375479525763e-4 0.0024627108600540773 0.00152438203408361 8569/7311/7316/5594/6233/5595 6 Potato_virus_Y R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 10/350 85/10654 4.5038727822894635e-4 0.0024632291883385587 0.001524702871717226 7311/1432/351/5600/5528/7316/5594/5609/6233/5595 10 Potato_virus_Y R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 10/350 85/10654 4.5038727822894635e-4 0.0024632291883385587 0.001524702871717226 7311/1432/351/5600/5528/7316/5594/5609/6233/5595 10 Potato_virus_Y R-HSA-975871 MyD88 cascade initiated on plasma membrane 10/350 85/10654 4.5038727822894635e-4 0.0024632291883385587 0.001524702871717226 7311/1432/351/5600/5528/7316/5594/5609/6233/5595 10 Potato_virus_Y R-HSA-170968 Frs2-mediated activation 4/350 12/10654 4.5967014199829807e-4 0.0024682893685484372 0.001527835049321297 4914/7529/5594/5595 4 Potato_virus_Y R-HSA-5689877 Josephin domain DUBs 4/350 12/10654 4.5967014199829807e-4 0.0024682893685484372 0.001527835049321297 7311/4287/7316/6233 4 Potato_virus_Y R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 4/350 12/10654 4.5967014199829807e-4 0.0024682893685484372 0.001527835049321297 834/839/843/835 4 Potato_virus_Y R-HSA-2219528 PI3K/AKT Signaling in Cancer 11/350 101/10654 4.639404026553262e-4 0.002476212028630235 0.0015327390601358592 2475/7249/2064/3667/2100/5728/842/207/84335/253260/64223 11 Potato_virus_Y R-HSA-195258 RHO GTPase Effectors 23/350 327/10654 4.8554626230174017e-4 0.002576011906582885 0.0015945137261847253 23191/1080/1432/348995/84617/79023/57122/5903/6232/7534/54908/1780/5600/5528/1781/4627/55746/4629/7529/5594/23279/5595/79902 23 Potato_virus_Y R-HSA-5656169 Termination of translesion DNA synthesis 6/350 32/10654 5.290890325770098e-4 0.002790314778947802 0.0017271640725101639 7311/9636/7706/7316/9246/6233 6 Potato_virus_Y R-HSA-448424 Interleukin-17 signaling 9/350 72/10654 5.510907607891429e-4 0.002889150379048406 0.0017883418646598786 7311/1432/5600/5528/7316/5594/5609/6233/5595 9 Potato_virus_Y R-HSA-170834 Signaling by TGF-beta Receptor Complex 9/350 73/10654 6.107677576911606e-4 0.003178269336123505 0.001967302274112328 57154/7048/1025/7311/7316/9040/10273/4609/6233 9 Potato_virus_Y R-HSA-8878166 Transcriptional regulation by RUNX2 12/350 121/10654 6.134131562947171e-4 0.003178269336123505 0.001967302274112328 57154/8493/7311/7316/595/861/10273/207/5594/5704/6233/5595 12 Potato_virus_Y R-HSA-198753 ERK/MAPK targets 5/350 22/10654 6.171362184232166e-4 0.003178969125133546 0.001967735433283329 1432/5600/5528/5594/5595 5 Potato_virus_Y R-HSA-5357905 Regulation of TNFR1 signaling 6/350 33/10654 6.290159638283853e-4 0.0032029203675399387 0.001982560902326611 7311/329/841/7316/1540/6233 6 Potato_virus_Y R-HSA-5654726 Negative regulation of FGFR1 signaling 6/350 33/10654 6.290159638283853e-4 0.0032029203675399387 0.001982560902326611 8569/7311/7316/5594/6233/5595 6 Potato_virus_Y R-HSA-5687128 MAPK6/MAPK4 signaling 10/350 89/10654 6.517811674667522e-4 0.003299874939288814 0.002042574365414604 7311/27161/192670/7316/26523/192669/8556/4609/5704/6233 10 Potato_virus_Y R-HSA-5663220 RHO GTPases Activate Formins 13/350 140/10654 6.922215384519154e-4 0.0034847061537977104 0.0021569821862048324 348995/84617/79023/57122/5903/6232/54908/1780/5528/1781/55746/23279/79902 13 Potato_virus_Y R-HSA-5654727 Negative regulation of FGFR2 signaling 6/350 34/10654 7.429725437560326e-4 0.003719060303773135 0.0023020439803561883 8569/7311/7316/5594/6233/5595 6 Potato_virus_Y R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 10/350 92/10654 8.473449416593801e-4 0.004217683248933768 0.0026106842968925906 7311/1432/351/5600/5528/7316/5594/5609/6233/5595 10 Potato_virus_Y R-HSA-169893 Prolonged ERK activation events 4/350 14/10654 8.822876468270256e-4 0.004342815861604137 0.0026881395555373123 4914/7529/5594/5595 4 Potato_virus_Y R-HSA-198323 AKT phosphorylates targets in the cytosol 4/350 14/10654 8.822876468270256e-4 0.004342815861604137 0.0026881395555373123 7249/842/207/84335 4 Potato_virus_Y R-HSA-73893 DNA Damage Bypass 7/350 48/10654 8.967661011438907e-4 0.004389694837643576 0.002717156956649998 7311/9636/7706/7316/9246/57599/6233 7 Potato_virus_Y R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 10/350 93/10654 9.223536359420464e-4 0.004465602849424334 0.002764142906677056 7311/1432/351/5600/5528/7316/5594/5609/6233/5595 10 Potato_virus_Y R-HSA-975155 MyD88 dependent cascade initiated on endosome 10/350 93/10654 9.223536359420464e-4 0.004465602849424334 0.002764142906677056 7311/1432/351/5600/5528/7316/5594/5609/6233/5595 10 Potato_virus_Y R-HSA-203927 MicroRNA (miRNA) biogenesis 5/350 24/10654 9.437107714562335e-4 0.004519609424379583 0.0027975721873610116 27161/192670/26523/192669/23405 5 Potato_virus_Y R-HSA-450302 activated TAK1 mediates p38 MAPK activation 5/350 24/10654 9.437107714562335e-4 0.004519609424379583 0.0027975721873610116 7311/1432/5600/7316/6233 5 Potato_virus_Y R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 6/350 36/10654 0.0010181859672778984 0.004850068639829129 0.003002121612630363 2335/3845/1445/7529/5594/5595 6 Rabbit_hemorrhagic_disease_virus R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 109/226 112/10654 2.7588082742309093e-191 1.9697891078008693e-188 1.3997321980834721e-188 6157/6156/6155/9349/6142/6137/6159/6147/1983/8661/4736/6175/8666/6158/6176/6167/3921/6170/6235/6129/6218/7458/6188/6209/6143/6189/6232/1977/7311/6139/1973/6206/6152/6204/8669/6194/6223/1974/200916/25873/9045/6217/6136/8894/6134/1964/8664/6193/1965/6181/6122/6187/6224/6173/6146/6133/6169/51065/3646/8662/6138/6154/6210/6124/6160/6231/6234/6229/6141/10480/6144/27335/6205/6191/8668/8665/8663/6202/6228/6233/1975/6165/6166/6128/9669/6135/23521/6168/6123/6201/1968/11224/8667/6125/6203/6164/6207/51386/1981/116832/6208/140801/6222/6161/51121/6230/6132/6130/6227 109 Rabbit_hemorrhagic_disease_virus R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 108/226 111/10654 2.398913345287836e-189 8.564120642677574e-187 6.085664381203879e-187 6157/6156/6155/9349/6142/6137/6159/6147/8661/4736/6175/8666/6158/6176/6167/3921/6170/6235/6129/6218/7458/6188/6209/6143/6189/6232/1977/7311/6139/1973/6206/6152/6204/8669/6194/6223/1974/200916/25873/9045/6217/6136/8894/6134/1964/8664/6193/1965/6181/6122/6187/6224/6173/6146/6133/6169/51065/3646/8662/6138/6154/6210/6124/6160/6231/6234/6229/6141/10480/6144/27335/6205/6191/26986/8668/8665/8663/6202/6228/6233/1975/6165/6166/6128/6135/23521/6168/6123/6201/1968/11224/8667/6125/6203/6164/6207/51386/1981/116832/6208/140801/6222/6161/51121/6230/6132/6130/6227 108 Rabbit_hemorrhagic_disease_virus R-HSA-72613 Eukaryotic Translation Initiation 110/226 119/10654 1.2166108791673684e-185 2.1716504193137525e-183 1.5431748519965042e-183 6157/6156/6155/9349/6142/6137/6159/6147/1983/8661/4736/6175/8666/6158/6176/6167/3921/6170/6235/6129/6218/7458/6188/6209/6143/6189/6232/1977/7311/6139/1973/6206/6152/6204/8669/6194/6223/1974/200916/25873/9045/6217/6136/8894/6134/1964/8664/6193/1965/6181/6122/6187/6224/6173/6146/6133/6169/51065/3646/8662/6138/6154/6210/6124/6160/6231/6234/6229/6141/10480/6144/27335/6205/6191/26986/8668/8665/8663/6202/6228/6233/1975/6165/6166/6128/9669/6135/23521/6168/6123/6201/1968/11224/8667/6125/6203/6164/6207/51386/1981/116832/6208/140801/6222/6161/51121/6230/6132/6130/6227 110 Rabbit_hemorrhagic_disease_virus R-HSA-72737 Cap-dependent Translation Initiation 110/226 119/10654 1.2166108791673684e-185 2.1716504193137525e-183 1.5431748519965042e-183 6157/6156/6155/9349/6142/6137/6159/6147/1983/8661/4736/6175/8666/6158/6176/6167/3921/6170/6235/6129/6218/7458/6188/6209/6143/6189/6232/1977/7311/6139/1973/6206/6152/6204/8669/6194/6223/1974/200916/25873/9045/6217/6136/8894/6134/1964/8664/6193/1965/6181/6122/6187/6224/6173/6146/6133/6169/51065/3646/8662/6138/6154/6210/6124/6160/6231/6234/6229/6141/10480/6144/27335/6205/6191/26986/8668/8665/8663/6202/6228/6233/1975/6165/6166/6128/9669/6135/23521/6168/6123/6201/1968/11224/8667/6125/6203/6164/6207/51386/1981/116832/6208/140801/6222/6161/51121/6230/6132/6130/6227 110 Rabbit_hemorrhagic_disease_virus R-HSA-72689 Formation of a pool of free 40S subunits 98/226 101/10654 3.734803135626725e-170 5.333298877674964e-168 3.789842339730699e-168 6157/6156/6155/9349/6142/6137/6159/6147/8661/4736/6175/8666/6158/6176/6167/3921/6170/6235/6129/6218/6188/6209/6143/6189/6232/7311/6139/6206/6152/6204/8669/6194/6223/200916/25873/9045/6217/6136/6134/1964/8664/6193/6181/6122/6187/6224/6173/6146/6133/6169/51065/3646/8662/6138/6154/6210/6124/6160/6231/6234/6229/6141/10480/6144/27335/6205/6191/8668/8665/8663/6202/6228/6233/6165/6166/6128/6135/23521/6168/6123/6201/11224/8667/6125/6203/6164/6207/51386/116832/6208/140801/6222/6161/51121/6230/6132/6130/6227 98 Rabbit_hemorrhagic_disease_virus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 90/226 95/10654 2.0588150191551083e-152 2.449989872794579e-150 1.7409628758469515e-150 6157/6156/6155/9349/6142/6137/6159/6147/4736/6175/6158/6176/6167/3921/6170/6235/6129/6218/6188/6209/6143/6189/6232/7311/6139/6206/6152/6204/6194/6223/200916/5976/25873/9045/2107/6217/6136/2935/6134/6193/6181/6122/6187/6224/6173/6146/6133/6169/51065/6138/6154/6210/6124/6160/6231/6234/6229/6141/6144/6205/6191/26986/6202/6228/6233/6165/6166/6128/6135/23521/6168/6123/6201/11224/6125/6203/6164/6207/1981/116832/23708/6208/140801/6222/6161/51121/6230/6132/6130/6227 90 Rabbit_hemorrhagic_disease_virus R-HSA-72764 Eukaryotic Translation Termination 87/226 93/10654 1.1982864915207653e-145 1.2222522213511807e-143 8.685324645308405e-144 6157/6156/6155/9349/6142/6137/6159/6147/4736/6175/6158/6176/6167/3921/6170/6235/6129/6218/6188/6209/6143/6189/6232/7311/6139/6206/6152/6204/6194/6223/200916/25873/9045/2107/6217/6136/2935/6134/6193/6181/6122/6187/6224/6173/6146/6133/6169/51065/6138/6154/6210/6124/6160/6231/6234/6229/6141/6144/6205/6191/6202/6228/6233/6165/6166/6128/6135/23521/6168/6123/6201/11224/6125/6203/6164/6207/116832/23708/6208/140801/6222/6161/51121/6230/6132/6130/6227 87 Rabbit_hemorrhagic_disease_virus R-HSA-156902 Peptide chain elongation 84/226 89/10654 2.7806738750879234e-141 2.2060012742364192e-139 1.567584570517403e-139 6157/6156/6155/9349/6142/6137/6159/6147/4736/6175/6158/6176/6167/3921/6170/6235/6129/6218/6188/6209/6143/6189/6232/7311/6139/6206/6152/6204/6194/6223/200916/25873/9045/6217/6136/6134/6193/6181/6122/6187/6224/6173/6146/6133/6169/51065/6138/6154/6210/6124/6160/6231/6234/6229/6141/6144/6205/6191/6202/6228/6233/6165/6166/6128/6135/23521/6168/6123/6201/11224/6125/6203/6164/6207/116832/6208/140801/6222/6161/51121/6230/6132/6130/6227 84 Rabbit_hemorrhagic_disease_virus R-HSA-192823 Viral mRNA Translation 84/226 89/10654 2.7806738750879234e-141 2.2060012742364192e-139 1.567584570517403e-139 6157/6156/6155/9349/6142/6137/6159/6147/4736/6175/6158/6176/6167/3921/6170/6235/6129/6218/6188/6209/6143/6189/6232/7311/6139/6206/6152/6204/6194/6223/200916/25873/9045/6217/6136/6134/6193/6181/6122/6187/6224/6173/6146/6133/6169/51065/6138/6154/6210/6124/6160/6231/6234/6229/6141/6144/6205/6191/6202/6228/6233/6165/6166/6128/6135/23521/6168/6123/6201/11224/6125/6203/6164/6207/116832/6208/140801/6222/6161/51121/6230/6132/6130/6227 84 Rabbit_hemorrhagic_disease_virus R-HSA-156842 Eukaryotic Translation Elongation 85/226 93/10654 8.811615142129325e-140 6.291493211480338e-138 4.4707352615856156e-138 6157/6156/6155/9349/6142/6137/6159/6147/4736/6175/6158/1937/6176/6167/3921/6170/6235/6129/6218/6188/6209/6143/6189/6232/7311/6139/6206/6152/6204/6194/6223/200916/25873/9045/6217/6136/6134/6193/6181/6122/6187/6224/6173/6146/6133/6169/51065/6138/6154/6210/6124/6160/6231/6234/6229/6141/6144/6205/6191/6202/6228/6233/6165/6166/6128/6135/23521/6168/6123/6201/11224/6125/6203/6164/6207/116832/6208/140801/6222/6161/51121/6230/6132/6130/6227 85 Rabbit_hemorrhagic_disease_virus R-HSA-2408557 Selenocysteine synthesis 84/226 93/10654 6.107893223890325e-137 3.9645779653251744e-135 2.817229219057548e-135 6157/6156/6155/9349/6142/6137/6159/6147/4736/6175/6158/6176/6167/3921/6170/6235/6129/6218/6188/6209/6143/6189/6232/7311/6139/6206/6152/6204/6194/6223/200916/25873/9045/6217/6136/6134/6193/6181/6122/6187/6224/6173/6146/6133/6169/51065/6138/6154/6210/6124/6160/6231/6234/6229/6141/6144/6205/6191/6202/6228/6233/6165/6166/6128/6135/23521/6168/6123/6201/11224/6125/6203/6164/6207/116832/6208/140801/6222/6161/51121/6230/6132/6130/6227 84 Rabbit_hemorrhagic_disease_virus R-HSA-927802 Nonsense-Mediated Decay (NMD) 90/226 115/10654 3.4893203609846975e-135 1.9164421059562106e-133 1.3618238169996959e-133 6157/6156/6155/9349/6142/6137/6159/6147/4736/6175/6158/6176/6167/3921/6170/6235/6129/6218/6188/6209/6143/6189/6232/7311/6139/6206/6152/6204/6194/6223/200916/5976/25873/9045/2107/6217/6136/2935/6134/6193/6181/6122/6187/6224/6173/6146/6133/6169/51065/6138/6154/6210/6124/6160/6231/6234/6229/6141/6144/6205/6191/26986/6202/6228/6233/6165/6166/6128/6135/23521/6168/6123/6201/11224/6125/6203/6164/6207/1981/116832/23708/6208/140801/6222/6161/51121/6230/6132/6130/6227 90 Rabbit_hemorrhagic_disease_virus R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 90/226 115/10654 3.4893203609846975e-135 1.9164421059562106e-133 1.3618238169996959e-133 6157/6156/6155/9349/6142/6137/6159/6147/4736/6175/6158/6176/6167/3921/6170/6235/6129/6218/6188/6209/6143/6189/6232/7311/6139/6206/6152/6204/6194/6223/200916/5976/25873/9045/2107/6217/6136/2935/6134/6193/6181/6122/6187/6224/6173/6146/6133/6169/51065/6138/6154/6210/6124/6160/6231/6234/6229/6141/6144/6205/6191/26986/6202/6228/6233/6165/6166/6128/6135/23521/6168/6123/6201/11224/6125/6203/6164/6207/1981/116832/23708/6208/140801/6222/6161/51121/6230/6132/6130/6227 90 Rabbit_hemorrhagic_disease_virus R-HSA-72766 Translation 116/226 291/10654 1.5862145635252812e-127 8.089694273978934e-126 5.748536989617937e-126 6157/6156/6155/9349/6142/6137/6159/6147/1983/8661/4736/6175/8666/6158/1937/6176/6167/3921/6170/6235/6129/6218/7458/6188/6209/6143/6189/6232/1977/7311/6139/1973/6206/6152/6204/8669/6194/6223/1974/200916/25873/9045/26589/2107/6217/6136/8894/2935/6134/51081/1964/8664/6193/1965/6181/6122/6187/6224/6173/6146/6133/6169/51065/3646/8662/6138/6154/6210/6124/6160/6231/6234/6229/6141/10480/6144/27335/6205/6191/26986/8668/8665/8663/6202/6228/6233/1975/6165/6166/6128/9669/6135/23521/6168/6123/6201/1968/11224/8667/6125/6203/6164/6207/51386/1981/116832/23708/6208/140801/6222/6161/51121/6230/6132/6130/6227 116 Rabbit_hemorrhagic_disease_virus R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 84/226 112/10654 9.621823567698843e-123 4.579988018224649e-121 3.254539620793574e-121 6157/6156/6155/9349/6142/6137/6159/6147/4736/6175/6158/6176/6167/3921/6170/6235/6129/6218/6188/6209/6143/6189/6232/7311/6139/6206/6152/6204/6194/6223/200916/25873/9045/6217/6136/6134/6193/6181/6122/6187/6224/6173/6146/6133/6169/51065/6138/6154/6210/6124/6160/6231/6234/6229/6141/6144/6205/6191/6202/6228/6233/6165/6166/6128/6135/23521/6168/6123/6201/11224/6125/6203/6164/6207/116832/6208/140801/6222/6161/51121/6230/6132/6130/6227 84 Rabbit_hemorrhagic_disease_virus R-HSA-2408522 Selenoamino acid metabolism 84/226 118/10654 2.1752840836437174e-119 9.707205223260089e-118 6.89794031787021e-118 6157/6156/6155/9349/6142/6137/6159/6147/4736/6175/6158/6176/6167/3921/6170/6235/6129/6218/6188/6209/6143/6189/6232/7311/6139/6206/6152/6204/6194/6223/200916/25873/9045/6217/6136/6134/6193/6181/6122/6187/6224/6173/6146/6133/6169/51065/6138/6154/6210/6124/6160/6231/6234/6229/6141/6144/6205/6191/6202/6228/6233/6165/6166/6128/6135/23521/6168/6123/6201/11224/6125/6203/6164/6207/116832/6208/140801/6222/6161/51121/6230/6132/6130/6227 84 Rabbit_hemorrhagic_disease_virus R-HSA-168273 Influenza Viral RNA Transcription and Replication 84/226 134/10654 7.247825620579726e-112 3.044086760643485e-110 2.163128141869615e-110 6157/6156/6155/9349/6142/6137/6159/6147/4736/6175/6158/6176/6167/3921/6170/6235/6129/6218/6188/6209/6143/6189/6232/7311/6139/6206/6152/6204/6194/6223/200916/25873/9045/6217/6136/6134/6193/6181/6122/6187/6224/6173/6146/6133/6169/51065/6138/6154/6210/6124/6160/6231/6234/6229/6141/6144/6205/6191/6202/6228/6233/6165/6166/6128/6135/23521/6168/6123/6201/11224/6125/6203/6164/6207/116832/6208/140801/6222/6161/51121/6230/6132/6130/6227 84 Rabbit_hemorrhagic_disease_virus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 90/226 171/10654 1.925931922425515e-110 7.639529958954541e-109 5.428650214088295e-109 6157/6156/7316/6155/9349/6142/6137/6159/6147/4736/6175/6158/6176/6167/3921/6170/6235/6129/6218/6188/6209/6143/6189/6232/7311/6139/6206/6152/6204/6194/6223/200916/25873/9045/2107/6217/6136/2935/6134/6193/6181/6122/6187/6224/6173/6146/6133/6169/51065/6138/6154/6210/6124/6160/6231/6234/6229/6141/6144/6205/6191/26986/6202/6228/6233/6165/6166/6128/6135/23521/6168/6123/6201/11224/6125/6203/6164/6207/1981/116832/23708/6208/140801/6222/6161/51121/6230/6132/6130/6227 90 Rabbit_hemorrhagic_disease_virus R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 91/226 185/10654 4.114998627516498e-108 1.5463731684456737e-106 1.0988528190930484e-106 6157/6156/23246/6155/9349/6142/6137/6159/6147/4736/6175/6158/6176/6167/3921/6170/6235/6129/6218/6188/6209/6143/6189/6232/7311/6139/6206/6152/6204/6194/6223/200916/25873/9045/83732/6217/6136/6134/9790/6193/6181/6122/6187/6224/6173/6146/6133/6169/51065/6138/6154/4691/6210/6124/6160/6231/6234/6229/6141/6144/51602/6205/6191/10528/6202/6228/6233/6165/6166/6128/6135/23521/6168/6123/55781/6201/11224/6125/6203/6164/6207/116832/6208/140801/6222/6161/51121/6230/6132/6130/6227 91 Rabbit_hemorrhagic_disease_virus R-HSA-168255 Influenza Life Cycle 84/226 144/10654 6.4504758088358776e-108 2.3028198637544084e-106 1.6363838630836283e-106 6157/6156/6155/9349/6142/6137/6159/6147/4736/6175/6158/6176/6167/3921/6170/6235/6129/6218/6188/6209/6143/6189/6232/7311/6139/6206/6152/6204/6194/6223/200916/25873/9045/6217/6136/6134/6193/6181/6122/6187/6224/6173/6146/6133/6169/51065/6138/6154/6210/6124/6160/6231/6234/6229/6141/6144/6205/6191/6202/6228/6233/6165/6166/6128/6135/23521/6168/6123/6201/11224/6125/6203/6164/6207/116832/6208/140801/6222/6161/51121/6230/6132/6130/6227 84 Rabbit_hemorrhagic_disease_virus R-HSA-8868773 rRNA processing in the nucleus and cytosol 92/226 195/10654 3.5493982682783316e-107 1.2067954112146327e-105 8.575488547920583e-106 6157/6156/23246/6155/9349/6142/6137/6159/6147/4736/6175/6158/6176/6167/3921/6170/6235/6129/6218/6188/6209/6143/6189/6232/7311/6139/6206/6152/6204/6194/6223/200916/25873/9045/83732/6217/6136/6134/9790/6193/6181/6122/6187/6224/6173/6146/6133/6169/51065/6138/6154/4691/6210/6124/6160/6231/6234/6229/6141/6144/51602/6205/6191/1736/10528/6202/6228/6233/6165/6166/6128/6135/23521/6168/6123/55781/6201/11224/6125/6203/6164/6207/116832/6208/140801/6222/6161/51121/6230/6132/6130/6227 92 Rabbit_hemorrhagic_disease_virus R-HSA-72312 rRNA processing 92/226 205/10654 1.454368328387704e-104 4.720086302131002e-103 3.3540934654682934e-103 6157/6156/23246/6155/9349/6142/6137/6159/6147/4736/6175/6158/6176/6167/3921/6170/6235/6129/6218/6188/6209/6143/6189/6232/7311/6139/6206/6152/6204/6194/6223/200916/25873/9045/83732/6217/6136/6134/9790/6193/6181/6122/6187/6224/6173/6146/6133/6169/51065/6138/6154/4691/6210/6124/6160/6231/6234/6229/6141/6144/51602/6205/6191/1736/10528/6202/6228/6233/6165/6166/6128/6135/23521/6168/6123/55781/6201/11224/6125/6203/6164/6207/116832/6208/140801/6222/6161/51121/6230/6132/6130/6227 92 Rabbit_hemorrhagic_disease_virus R-HSA-168254 Influenza Infection 84/226 155/10654 4.696903822947019e-104 1.4580823172105096e-102 1.036113337602043e-102 6157/6156/6155/9349/6142/6137/6159/6147/4736/6175/6158/6176/6167/3921/6170/6235/6129/6218/6188/6209/6143/6189/6232/7311/6139/6206/6152/6204/6194/6223/200916/25873/9045/6217/6136/6134/6193/6181/6122/6187/6224/6173/6146/6133/6169/51065/6138/6154/6210/6124/6160/6231/6234/6229/6141/6144/6205/6191/6202/6228/6233/6165/6166/6128/6135/23521/6168/6123/6201/11224/6125/6203/6164/6207/116832/6208/140801/6222/6161/51121/6230/6132/6130/6227 84 Rabbit_hemorrhagic_disease_virus R-HSA-376176 Signaling by ROBO receptors 90/226 218/10654 6.020224698555066e-98 1.7910168478201323e-96 1.2726966248699748e-96 6157/6156/7316/6155/9349/6142/6137/6159/6147/4736/6175/6158/6176/6167/3921/6170/6235/6129/6218/6188/6209/6143/6189/6232/7311/6139/6206/6152/6204/6194/6223/200916/25873/9045/2107/6217/6136/2935/6134/6193/6181/6122/6187/6224/6173/6146/6133/6169/51065/6138/6154/6210/6124/6160/6231/6234/6229/6141/6144/6205/6191/26986/6202/6228/6233/6165/6166/6128/6135/23521/6168/6123/6201/11224/6125/6203/6164/6207/1981/116832/23708/6208/140801/6222/6161/51121/6230/6132/6130/6227 90 Rabbit_hemorrhagic_disease_virus R-HSA-72649 Translation initiation complex formation 56/226 58/10654 2.0899014283896928e-94 5.739190845654772e-93 4.078269184145069e-93 8661/8666/3921/6235/6218/7458/6188/6209/6189/6232/1977/1973/6206/6204/8669/6194/6223/1974/6217/8894/1964/8664/6193/1965/6187/6224/51065/3646/8662/6210/6231/6234/6229/10480/27335/6205/6191/26986/8668/8665/8663/6202/6228/6233/1975/6201/1968/8667/6203/6207/51386/1981/6208/6222/6230/6227 56 Rabbit_hemorrhagic_disease_virus R-HSA-72702 Ribosomal scanning and start codon recognition 56/226 58/10654 2.0899014283896928e-94 5.739190845654772e-93 4.078269184145069e-93 1983/8661/8666/3921/6235/6218/7458/6188/6209/6189/6232/1977/1973/6206/6204/8669/6194/6223/1974/6217/8894/1964/8664/6193/1965/6187/6224/51065/3646/8662/6210/6231/6234/6229/10480/27335/6205/6191/8668/8665/8663/6202/6228/6233/1975/6201/1968/8667/6203/6207/51386/1981/6208/6222/6230/6227 56 Rabbit_hemorrhagic_disease_virus R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 56/226 59/10654 4.045354994947078e-93 1.0697716542193384e-91 7.601797690309911e-92 8661/8666/3921/6235/6218/7458/6188/6209/6189/6232/1977/1973/6206/6204/8669/6194/6223/1974/6217/8894/1964/8664/6193/1965/6187/6224/51065/3646/8662/6210/6231/6234/6229/10480/27335/6205/6191/26986/8668/8665/8663/6202/6228/6233/1975/6201/1968/8667/6203/6207/51386/1981/6208/6222/6230/6227 56 Rabbit_hemorrhagic_disease_virus R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 49/226 51/10654 5.022346692372227e-82 1.2806984065549178e-80 9.1006432545993e-81 8661/8666/3921/6235/6218/6188/6209/6189/6232/6206/6204/8669/6194/6223/6217/8894/1964/8664/6193/1965/6187/6224/51065/3646/8662/6210/6231/6234/6229/10480/27335/6205/6191/8668/8665/8663/6202/6228/6233/6201/1968/8667/6203/6207/51386/6208/6222/6230/6227 49 Rabbit_hemorrhagic_disease_virus R-HSA-71291 Metabolism of amino acids and derivatives 86/226 372/10654 3.1186209586586364e-68 7.678259877525057e-67 5.456171695366471e-67 6157/6156/6155/9349/6142/6137/6159/6147/4736/6175/6158/6176/6167/3921/6170/6235/6129/6218/6188/6209/6143/6189/6232/7311/6139/6206/6152/6204/6194/5160/6223/200916/25873/9045/6217/6136/6134/6193/6181/6122/6187/6224/6173/6146/6133/6169/51065/6138/6154/6210/6124/1738/6160/6231/6234/6229/6141/6144/6205/6191/6202/6228/6233/6165/6166/6128/6135/23521/6168/6123/6201/11224/6125/6203/6164/6207/116832/6208/140801/6222/6161/51121/6230/6132/6130/6227 86 Rabbit_hemorrhagic_disease_virus R-HSA-5663205 Infectious disease 86/226 383/10654 4.59795054966967e-67 1.0943122308213814e-65 7.776183034879934e-66 6157/6156/7316/6155/9349/6142/6137/6159/6147/4736/6175/6158/6176/6167/3921/6170/6235/6129/6218/6188/6209/6143/6189/6232/7311/6139/6206/6152/6204/6194/6223/200916/25873/9045/6217/6136/6134/6193/6181/6122/6187/6224/6173/6146/6133/6169/51065/6138/6154/6210/6124/6160/6231/6234/6229/6141/6144/6205/6191/6202/6228/6233/6165/6166/6128/6135/23521/6168/6123/6201/11224/6125/6203/6164/6207/4869/116832/6208/140801/6222/6161/51121/6230/6132/6130/6227 86 Rabbit_hemorrhagic_disease_virus R-HSA-168638 NOD1/2 Signaling Pathway 9/226 36/10654 4.243606086923929e-8 9.773983051818339e-7 6.945392644812679e-7 7316/1540/841/7311/842/834/835/6233/837 9 Rabbit_hemorrhagic_disease_virus R-HSA-429947 Deadenylation of mRNA 7/226 25/10654 6.115548024789122e-7 1.3645316530310728e-5 9.69636232877749e-6 10605/1977/1973/1974/26986/1975/1981 7 Rabbit_hemorrhagic_disease_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 9/226 55/10654 2.018996443135426e-6 4.368374122420286e-5 3.1041667801954566e-5 7316/1540/841/7311/842/834/835/6233/837 9 Rabbit_hemorrhagic_disease_virus R-HSA-264870 Caspase-mediated cleavage of cytoskeletal proteins 5/226 12/10654 2.8826970407275117e-6 6.053663785527775e-5 4.3017336644912106e-5 841/5339/836/839/840 5 Rabbit_hemorrhagic_disease_virus R-HSA-6790901 rRNA modification in the nucleus and cytosol 9/226 62/10654 5.662840300824622e-6 1.1552194213682227e-4 8.208989548864564e-5 6194/9790/6187/51602/1736/10528/6201/6203/6208 9 Rabbit_hemorrhagic_disease_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 10/226 80/10654 6.794808004591047e-6 1.3476369209105575e-4 9.576308357347618e-5 8672/7316/1982/1977/7311/1973/1974/6233/6059/1981 10 Rabbit_hemorrhagic_disease_virus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 5/226 16/10654 1.483071828720569e-5 2.86192779920672e-4 2.0336859785016057e-4 7316/57154/7048/7311/6233 5 Rabbit_hemorrhagic_disease_virus R-HSA-1169408 ISG15 antiviral mechanism 9/226 72/10654 1.9768349150063233e-5 3.7143687613539866e-4 2.6394305513380826e-4 8672/7316/1982/1977/7311/1973/1974/6233/1981 9 Rabbit_hemorrhagic_disease_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 6/226 32/10654 4.8680935381437414e-5 8.91235586214008e-4 6.333120338421819e-4 7316/57154/7048/7311/6233/9040 6 Rabbit_hemorrhagic_disease_virus R-HSA-5689877 Josephin domain DUBs 4/226 12/10654 8.53781239137361e-5 0.0014868287920587215 0.001056540583476786 7316/7311/6233/4287 4 Rabbit_hemorrhagic_disease_virus R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 4/226 12/10654 8.53781239137361e-5 0.0014868287920587215 0.001056540583476786 843/834/835/839 4 Rabbit_hemorrhagic_disease_virus R-HSA-166208 mTORC1-mediated signalling 5/226 23/10654 1.0119115630691313e-4 0.0017202496572175233 0.0012224094571411561 1977/6194/6198/1975/1981 5 Rabbit_hemorrhagic_disease_virus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 4/226 13/10654 1.2127790666203932e-4 0.002013777333876653 0.0014309902328299379 7316/7311/6233/2064 4 Rabbit_hemorrhagic_disease_virus R-HSA-429914 Deadenylation-dependent mRNA decay 7/226 56/10654 1.6874044761810403e-4 0.0027381972636210516 0.0019457630562661758 10605/1977/1973/1974/26986/1975/1981 7 Rabbit_hemorrhagic_disease_virus R-HSA-165159 mTOR signalling 6/226 40/10654 1.789727809113127e-4 0.0028397014571261616 0.0020178919391638066 51422/1977/6194/6198/1975/1981 6 Rabbit_hemorrhagic_disease_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 5/226 26/10654 1.878134459582833e-4 0.0029151913133524843 0.002071535033224086 7316/57154/7048/7311/6233 5 Rabies_virus R-HSA-6809371 Formation of the cornified envelope 40/91 129/10654 1.8060677009455285e-54 3.7204994639477884e-52 3.4790567291898076e-52 23581/353135/353141/6705/1823/5493/353142/3713/6706/7051/7062/1828/353137/6700/1475/254910/6707/353139/353145/5266/6698/353133/26239/6703/353143/2125/84648/353134/6701/6704/6699/353132/126638/199834/353131/353140/1041/149018/448835/353144 40 Rabies_virus R-HSA-6805567 Keratinization 40/91 214/10654 1.343567926073879e-44 1.3838749638560955e-42 1.2940680551132625e-42 23581/353135/353141/6705/1823/5493/353142/3713/6706/7051/7062/1828/353137/6700/1475/254910/6707/353139/353145/5266/6698/353133/26239/6703/353143/2125/84648/353134/6701/6704/6699/353132/126638/199834/353131/353140/1041/149018/448835/353144 40 Rabies_virus R-HSA-9033658 Blood group systems biosynthesis 14/91 22/10654 1.1718733816407733e-24 8.046863887266644e-23 7.524660661061807e-23 10402/6484/28/8707/2524/2526/2528/2523/8708/10317/2527/10690/170384/2525 14 Rabies_virus R-HSA-9037629 Lewis blood group biosynthesis 12/91 18/10654 1.2665747068310506e-21 6.52285974017991e-20 6.099557140791639e-20 10402/6484/8707/2524/2526/2528/8708/10317/2527/10690/170384/2525 12 Rabies_virus R-HSA-71387 Metabolism of carbohydrates 25/91 295/10654 1.2882485872948821e-18 5.3075841796549146e-17 4.963147188946598e-17 10402/6484/10678/8702/28/6548/8707/2524/2526/6483/2683/8703/79369/6482/2528/8704/2523/8708/10317/2527/10690/170384/10331/2525/55454 25 Rabies_virus R-HSA-2022854 Keratan sulfate biosynthesis 11/91 28/10654 1.8059533363859572e-16 6.200439788258453e-15 5.798060711554916e-15 10402/6484/10678/8702/6483/2683/8703/79369/6482/8704/10331 11 Rabies_virus R-HSA-1638074 Keratan sulfate/keratin metabolism 11/91 34/10654 2.3082055748996586e-15 6.792719263276138e-14 6.351904063257707e-14 10402/6484/10678/8702/6483/2683/8703/79369/6482/8704/10331 11 Rabies_virus R-HSA-1630316 Glycosaminoglycan metabolism 13/91 124/10654 3.3857130459060306e-11 8.718211093208029e-10 8.152440623694785e-10 10402/6484/10678/8702/6548/6483/2683/8703/79369/6482/8704/10331/55454 13 Rabies_virus R-HSA-975576 N-glycan antennae elongation in the medial/trans-Golgi 6/91 26/10654 6.595858598647501e-8 1.5097187459126503e-6 1.4117451737456054e-6 6484/8702/2683/8703/8704/2525 6 Rabies_virus R-HSA-975577 N-Glycan antennae elongation 5/91 15/10654 1.1422578209118859e-7 2.353051111078485e-6 2.20034927607237e-6 6484/8702/2683/8703/8704 5 Rabies_virus R-HSA-6799198 Complex I biogenesis 6/91 55/10654 6.808855325126867e-6 1.2751129063419403e-4 1.1923641382758056e-4 4714/4711/4712/4701/4724/4715 6 Rabies_virus R-HSA-913709 O-linked glycosylation of mucins 6/91 64/10654 1.6557850719466725e-5 2.8424310401751216e-4 2.6579707733880795e-4 6484/10678/6483/79369/6482/10331 6 Rabies_virus R-HSA-4085001 Sialic acid metabolism 4/91 33/10654 1.6863212911638392e-4 0.0026721706613826992 0.002498759484072734 10402/6484/6483/6482 4 Rabies_virus R-HSA-611105 Respiratory electron transport 6/91 100/10654 2.0588099680738734e-4 0.003029391810165842 0.0028327986778760817 4714/4711/4712/4701/4724/4715 6 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5357801 Programmed Cell Death 45/208 181/10654 7.986541878348989e-38 6.700708635934802e-35 4.413615248561283e-35 8837/7316/54205/841/5339/23643/7099/10018/4137/355/598/8772/56616/836/197259/330/842/331/929/581/637/317/8743/3002/5594/7186/11035/839/10059/8737/10134/329/7157/5599/8797/5595/8795/353376/8717/7431/148022/356/840/596/207 45 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-73887 Death Receptor Signalling 41/208 141/10654 1.6570782228782247e-37 6.951443144974152e-35 4.5787687737424625e-35 8837/7316/9099/387/5584/1540/843/841/10018/7124/8517/355/8772/1147/836/3551/330/7128/25999/4615/7189/7185/7132/331/396/8743/7186/835/8878/4790/8737/8567/329/5599/5970/8797/8767/8795/8793/8717/356 41 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-109581 Apoptosis 42/208 178/10654 2.9965038032299515e-34 8.380222303033099e-32 5.519875427002542e-32 8837/7316/54205/841/5339/23643/7099/10018/4137/355/598/8772/56616/836/842/331/929/581/637/317/8743/3002/5594/7186/839/10059/8737/10134/329/7157/5599/8797/5595/8795/353376/8717/7431/148022/356/840/596/207 42 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 24/208 55/10654 3.59187541222207e-27 5.839936552767203e-25 3.8466428582934343e-25 7316/351/1540/841/8517/598/1147/3551/330/7128/7189/842/834/1432/835/4790/10392/29108/329/5970/8767/837/596/58484 24 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 16/208 17/10654 4.16573634152908e-27 5.839936552767203e-25 3.8466428582934343e-25 8837/841/23643/7099/355/8772/929/8743/7186/8737/8797/8795/353376/8717/148022/356 16 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5213460 RIPK1-mediated regulated necrosis 17/208 20/10654 4.872414287171683e-27 5.839936552767203e-25 3.8466428582934343e-25 8837/7316/841/355/8772/197259/330/331/8743/7186/11035/8737/329/8797/8795/8717/356 17 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5218859 Regulated Necrosis 17/208 20/10654 4.872414287171683e-27 5.839936552767203e-25 3.8466428582934343e-25 8837/7316/841/355/8772/197259/330/331/8743/7186/11035/8737/329/8797/8795/8717/356 17 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 18/208 27/10654 3.247071304141386e-25 3.4053660302182783e-23 2.243042677202931e-23 8837/841/23643/7099/355/8772/836/842/929/8743/7186/8737/8797/8795/353376/8717/148022/356 18 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5357905 Regulation of TNFR1 signaling 19/208 33/10654 9.309769408996146e-25 8.678773926830852e-23 5.716525075699387e-23 7316/9099/1540/841/7124/8517/1147/3551/330/7128/25999/7185/7132/331/7186/8737/8567/329/8717 19 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-166166 MyD88-independent TLR4 cascade 27/208 99/10654 5.2476663856547504e-24 4.002538270513032e-22 2.6363874186303773e-22 7316/351/841/23643/7099/8517/8772/1147/3551/330/7189/929/5594/1432/11035/5609/4790/8737/10392/329/5599/5970/8767/5595/353376/5515/148022 27 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 27/208 99/10654 5.2476663856547504e-24 4.002538270513032e-22 2.6363874186303773e-22 7316/351/841/23643/7099/8517/8772/1147/3551/330/7189/929/5594/1432/11035/5609/4790/8737/10392/329/5599/5970/8767/5595/353376/5515/148022 27 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5675482 Regulation of necroptotic cell death 15/208 18/10654 1.0650450786507996e-23 7.446440174900175e-22 4.904812862207629e-22 8837/7316/841/355/8772/330/331/8743/7186/8737/329/8797/8795/8717/356 15 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-75893 TNF signaling 20/208 43/10654 1.666693340993543e-23 1.0756582408412172e-21 7.08513363580251e-22 7316/9099/1540/841/7124/8517/8772/1147/3551/330/7128/25999/7185/7132/331/7186/8737/8567/329/8717 20 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-8948216 Collagen chain trimerization 20/208 44/10654 3.0040971007654074e-23 1.8003124768158405e-21 1.1858278029337134e-21 1288/256076/1281/1301/1280/1290/1289/1293/1284/1302/1292/1291/1286/1287/1285/1278/131873/1282/1294/1277 20 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 28/208 129/10654 6.865589515321094e-22 3.8401530689029315e-20 2.529427716170929e-20 7316/351/841/23643/7099/8517/8772/1147/3551/330/4615/7189/929/5594/1432/11035/5609/4790/8737/10392/329/5599/5970/8767/5595/353376/5515/148022 28 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-168898 Toll-like Receptor Cascades 30/208 155/10654 7.414087357012151e-22 3.8877620578332465e-20 2.5607867515995913e-20 7316/351/841/23643/7099/8517/8772/1147/3551/330/4615/7189/929/7098/5594/1432/11035/5609/4790/8737/10392/329/5599/5970/8767/5595/5289/353376/5515/148022 30 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12/208 12/10654 2.2329650912399255e-21 1.1020339479707632e-19 7.258864847683968e-20 64135/843/841/7706/8517/8772/1147/3551/84282/57506/8737/23586 12 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-2022090 Assembly of collagen fibrils and other multimeric structures 21/208 61/10654 2.802863035616164e-21 1.3064456038233122e-19 8.605281249698749e-20 1288/5339/256076/1281/1301/1280/1290/1289/1293/1284/1302/1292/1291/1286/1287/1285/1278/131873/1282/1294/1277 21 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 24/208 94/10654 1.0962808278545554e-20 4.840945339841958e-19 3.1886284466683744e-19 7316/351/841/8517/8772/1147/3551/330/7189/7098/5594/1432/11035/5609/4790/8737/10392/329/5599/5970/8767/5595/5515/148022 24 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-168638 NOD1/2 Signaling Pathway 17/208 36/10654 2.794576954432372e-20 1.1393830692117738e-18 7.5048756205530545e-19 7316/1540/841/8517/1147/3551/330/7128/7189/842/834/1432/835/10392/329/8767/837 17 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 16/208 30/10654 2.851852735810161e-20 1.1393830692117738e-18 7.5048756205530545e-19 7316/9099/1540/7124/8517/1147/3551/330/7128/7185/7132/331/7186/8737/329/8717 16 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-109606 Intrinsic Pathway for Apoptosis 19/208 53/10654 9.624233774031732e-20 3.670332789278465e-18 2.41757068486443e-18 54205/841/10018/598/56616/836/842/331/581/637/317/3002/5594/7157/5599/5595/840/596/207 19 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-3371378 Regulation by c-FLIP 11/208 11/10654 1.2063678916785024e-19 4.048570644473055e-18 2.6667079710787944e-18 8837/841/355/8772/8743/7186/8737/8797/8795/8717/356 11 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5218900 CASP8 activity is inhibited 11/208 11/10654 1.2063678916785024e-19 4.048570644473055e-18 2.6667079710787944e-18 8837/841/355/8772/8743/7186/8737/8797/8795/8717/356 11 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-69416 Dimerization of procaspase-8 11/208 11/10654 1.2063678916785024e-19 4.048570644473055e-18 2.6667079710787944e-18 8837/841/355/8772/8743/7186/8737/8797/8795/8717/356 11 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-1442490 Collagen degradation 20/208 64/10654 2.381759918304881e-19 7.685756044068443e-18 5.062445170486084e-18 1288/256076/1281/1301/1280/1290/1289/1293/1284/1302/1292/1291/1286/1287/1285/1278/131873/1282/1294/1277 20 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 23/208 97/10654 4.508310574962709e-19 1.4009157675532268e-17 9.227536264543554e-18 7316/351/23643/7099/8517/1147/3551/4615/7189/929/5594/1432/5609/4790/10392/5599/5970/8767/5595/5289/353376/5515/148022 23 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-1650814 Collagen biosynthesis and modifying enzymes 20/208 67/10654 6.686340115951738e-19 2.0035140561726817e-17 1.319672391306264e-17 1288/256076/1281/1301/1280/1290/1289/1293/1284/1302/1292/1291/1286/1287/1285/1278/131873/1282/1294/1277 20 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 21/208 78/10654 9.433948813246312e-19 2.729338984246088e-17 1.7977579408182626e-17 64135/7316/351/1540/843/841/7706/8517/8772/1147/3551/7128/7189/84282/57506/7186/4790/8737/23586/5970/9474 21 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 22/208 92/10654 2.2555076544773396e-18 6.307903073688293e-17 4.1548825214056255e-17 7316/351/23643/7099/8517/1147/3551/4615/7189/929/5594/1432/5609/4790/10392/5599/5970/8767/5595/353376/5515/148022 22 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-937041 IKK complex recruitment mediated by RIP1 14/208 25/10654 2.78129937904015e-18 7.385143680069846e-17 4.864438155745146e-17 7316/23643/7099/8517/1147/3551/330/7189/929/11035/8737/329/353376/148022 14 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 22/208 93/10654 2.9047644987163875e-18 7.385143680069846e-17 4.864438155745146e-17 7316/351/23643/7099/8517/1147/3551/4615/7189/929/5594/1432/5609/4790/10392/5599/5970/8767/5595/353376/5515/148022 22 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-975155 MyD88 dependent cascade initiated on endosome 22/208 93/10654 2.9047644987163875e-18 7.385143680069846e-17 4.864438155745146e-17 7316/351/23643/7099/8517/1147/3551/4615/7189/929/5594/1432/5609/4790/10392/5599/5970/8767/5595/353376/5515/148022 22 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-3000178 ECM proteoglycans 20/208 76/10654 1.0787584203928232e-17 2.6619950432634667e-16 1.7533999093072204e-16 351/1288/256076/1281/1280/1290/1289/3685/1293/1284/1292/1291/1286/1287/1285/1278/3690/131873/1282/1277 20 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-1474290 Collagen formation 21/208 90/10654 2.390729675072261e-17 5.730920563958934e-16 3.774836329061465e-16 1288/5339/256076/1281/1301/1280/1290/1289/1293/1284/1302/1292/1291/1286/1287/1285/1278/131873/1282/1294/1277 21 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 16/208 44/10654 6.42843750460945e-17 1.4981830739909249e-15 9.868215467602227e-16 843/8794/355/8738/834/581/637/317/835/839/7157/8797/8795/8793/472/58484 16 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-933542 TRAF6 mediated NF-kB activation 13/208 24/10654 8.499515295638316e-17 1.9273225224433912e-15 1.2694866373286248e-15 64135/351/7706/8517/1147/3551/7189/84282/57506/7186/4790/23586/5970 13 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-216083 Integrin cell surface interactions 20/208 85/10654 1.1919893923700213e-16 2.631787105785389e-15 1.7335025789314715e-15 1288/256076/1281/1280/1290/1289/3685/1293/1284/1292/1291/1286/1287/1285/1278/3690/131873/1282/1294/1277 20 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5689896 Ovarian tumor domain proteases 15/208 38/10654 1.4327686981499945e-16 3.0822895839688345e-15 2.0302390459615305e-15 64135/7316/5728/387/7706/8517/7128/7189/84282/57506/8737/10392/23586/7157/8767 15 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 20/208 95/10654 1.2254347834325957e-15 2.5076580080486534e-14 1.6517413640619067e-14 7316/351/23643/7099/8517/1147/3551/4615/7189/929/5594/1432/5609/4790/10392/5599/5970/8767/5595/5515 20 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 20/208 95/10654 1.2254347834325957e-15 2.5076580080486534e-14 1.6517413640619067e-14 7316/351/23643/7099/8517/1147/3551/4615/7189/929/5594/1432/5609/4790/10392/5599/5970/8767/5595/5515 20 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5357786 TNFR1-induced proapoptotic signaling 10/208 13/10654 1.7622412479978178e-15 3.520286683500402e-14 2.3187384842076548e-14 9099/1540/841/7124/8772/7128/7132/7186/8737/8717 10 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-375165 NCAM signaling for neurite out-growth 17/208 63/10654 2.0737759481438934e-15 4.046274466262155e-14 2.6651955269903158e-14 256076/1281/1280/1290/1289/1293/1284/1292/1291/6714/5594/1286/1287/5595/1285/131873/1282 17 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 20/208 98/10654 2.3278472094216138e-15 4.3401417971216315e-14 2.858759730868649e-14 7316/351/23643/7099/8517/1147/3551/4615/7189/929/5594/1432/5609/4790/10392/5599/5970/8767/5595/5515 20 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 20/208 98/10654 2.3278472094216138e-15 4.3401417971216315e-14 2.858759730868649e-14 7316/351/23643/7099/8517/1147/3551/4615/7189/929/5594/1432/5609/4790/10392/5599/5970/8767/5595/5515 20 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-2562578 TRIF-mediated programmed cell death 9/208 10/10654 3.4106955113258807e-15 6.22081203044003e-14 4.097517490723312e-14 841/23643/7099/8772/929/11035/8737/353376/148022 9 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-3000171 Non-integrin membrane-ECM interactions 16/208 59/10654 1.3086064927778613e-14 2.336001803065161e-13 1.538675047499165e-13 1288/1281/1301/1280/1290/1289/3685/1284/1302/1286/1287/1285/1278/3690/1282/1277 16 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 11/208 20/10654 1.7370270556943998e-14 3.03617854109917e-13 1.999866675963947e-13 7316/8517/1147/3551/330/7189/7098/11035/8737/329/148022 11 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-449147 Signaling by Interleukins 38/208 461/10654 2.4359029526501714e-14 4.1337400130915405e-13 2.722807235271386e-13 7316/351/11009/4478/7124/8517/6657/598/1147/836/3551/4615/7189/7132/5783/3553/834/3320/5594/1432/5609/8878/4790/10392/4609/7157/5599/5970/8767/5595/5515/1278/7431/356/596/4170/3598/207 38 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-419037 NCAM1 interactions 14/208 42/10654 2.4634922604836353e-14 4.1337400130915405e-13 2.722807235271386e-13 256076/1281/1280/1290/1289/1293/1284/1292/1291/1286/1287/1285/131873/1282 14 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 9/208 12/10654 7.253196070827468e-14 1.1932218634165186e-12 7.859500386345554e-13 843/8738/834/317/835/839/7157/472/58484 9 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 10/208 17/10654 1.1193181616663451e-13 1.805976803150122e-12 1.1895587750502655e-12 8517/1147/3551/4615/7098/11035/4790/8737/5970/148022 10 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-186797 Signaling by PDGF 15/208 58/10654 1.9547657241580652e-13 3.094431023714371e-12 2.0382363558748442e-12 256076/1281/1280/1290/1289/1293/1284/1292/1291/6714/1286/1287/1285/131873/1282 15 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-111461 Cytochrome c-mediated apoptotic response 9/208 13/10654 2.3176382949389753e-13 3.6009232026922227e-12 2.3718520562240973e-12 54205/56616/836/842/331/317/5594/5595/840 9 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5260271 Diseases of Immune System 11/208 24/10654 2.410756611540306e-13 3.611829994789852e-12 2.3790361298095125e-12 23643/7099/8517/1147/3551/4615/929/7098/4790/5970/148022 11 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5602358 Diseases associated with the TLR signaling cascade 11/208 24/10654 2.410756611540306e-13 3.611829994789852e-12 2.3790361298095125e-12 23643/7099/8517/1147/3551/4615/929/7098/4790/5970/148022 11 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-111471 Apoptotic factor-mediated response 10/208 18/10654 2.4758937075938857e-013 3.6443417906513506e-12 2.400450963041163e-12 54205/56616/836/842/331/581/317/5594/5595/840 10 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-1474228 Degradation of the extracellular matrix 21/208 140/10654 2.8403454190484864e-13 4.053420289963383e-12 2.6699023301308276e-12 1288/256076/1281/1301/1280/1290/1289/836/1293/1284/1302/1292/1291/1286/1287/1285/1278/131873/1282/1294/1277 21 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 37/208 473/10654 2.85043858293015e-13 4.053420289963383e-12 2.6699023301308276e-12 2475/7316/387/5900/1956/256076/1281/5725/1301/1280/1290/1289/3685/1293/1284/1302/581/1292/1291/6714/1111/3320/5594/1286/1432/1287/5595/1285/5289/5515/1278/3690/1213/131873/1282/207/1277 37 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 17/208 85/10654 4.4845098581838583e-13 6.0685544693810604e-12 3.997228651182557e-12 7316/351/8517/1147/3551/4615/7189/5594/1432/5609/4790/10392/5599/5970/8767/5595/5515 17 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 17/208 85/10654 4.4845098581838583e-13 6.0685544693810604e-12 3.997228651182557e-12 7316/351/8517/1147/3551/4615/7189/5594/1432/5609/4790/10392/5599/5970/8767/5595/5515 17 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-975871 MyD88 cascade initiated on plasma membrane 17/208 85/10654 4.4845098581838583e-13 6.0685544693810604e-12 3.997228651182557e-12 7316/351/8517/1147/3551/4615/7189/5594/1432/5609/4790/10392/5599/5970/8767/5595/5515 17 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-2214320 Anchoring fibril formation 9/208 15/10654 1.5682361056776188e-12 2.0884922105770197e-11 1.3756457067347535e-11 1288/1284/1286/1287/1285/1278/1282/1294/1277 9 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 10/208 21/10654 1.896226378923328e-12 2.4858342686198002e-11 1.6373665278532023e-11 8517/1147/3551/4615/7098/11035/4790/8737/5970/148022 10 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-193639 p75NTR signals via NF-kB 9/208 16/10654 3.5242626661888294e-12 4.549009810665274e-11 2.996336679755685e-11 7316/5584/3551/4615/7189/8878/4790/5970/8767 9 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-3700989 Transcriptional Regulation by TP53 31/208 365/10654 3.63702758728129e-12 4.623433554134852e-11 3.0453580276278745e-11 2475/7316/54205/1616/5728/9099/843/8794/641/355/8738/1025/834/80196/581/637/317/1111/1432/835/839/7157/8797/1107/8795/8793/472/5515/1027/58484/207 31 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-450294 MAP kinase activation 14/208 64/10654 1.528678014081634e-11 1.9142699310664046e-10 1.2608891710806878e-10 7316/8517/1147/3551/7189/5594/1432/5609/4790/10392/5599/8767/5595/5515 14 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-448424 Interleukin-17 signaling 14/208 72/10654 8.320415511123782e-11 1.0265924432107137e-9 6.761947590309575e-10 7316/8517/1147/3551/7189/5594/1432/5609/4790/10392/5599/8767/5595/5515 14 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-111458 Formation of apoptosome 7/208 11/10654 3.019854687902088e-10 3.619511547356931e-9 2.3840958062384903e-9 54205/56616/842/331/317/5594/5595 7 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-9627069 Regulation of the apoptosome activity 7/208 11/10654 3.019854687902088e-10 3.619511547356931e-9 2.3840958062384903e-9 54205/56616/842/331/317/5594/5595 7 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 10/208 33/10654 4.055994063474731e-10 4.792928196134224e-9 3.157000568308723e-9 7316/351/8517/1147/3551/7189/4790/10392/5970/8767 10 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-193704 p75 NTR receptor-mediated signalling 15/208 97/10654 5.204331147883347e-10 6.064491434825178e-9 3.994552416138534e-9 7316/387/5584/10018/836/3551/4615/7189/396/835/8878/4790/5599/5970/8767 15 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-2243919 Crosslinking of collagen fibrils 8/208 18/10654 6.828632159857648e-10 7.848249838521325e-9 5.1694764007574116e-9 1288/1284/1286/1287/1285/1278/1282/1277 8 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-264870 Caspase-mediated cleavage of cytoskeletal proteins 7/208 12/10654 7.128017615181949e-10 8.081630782618454e-9 5.323199499246833e-9 841/5339/4137/836/839/7431/840 7 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-1474244 Extracellular matrix organization 25/208 301/10654 8.580700609063913e-10 9.598943748006165e-9 6.322621501415514e-9 351/1288/5339/256076/1281/1301/1280/1290/1289/3685/836/1293/1284/1302/1292/1291/1286/1287/1285/1278/3690/131873/1282/1294/1277 25 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5607764 CLEC7A (Dectin-1) signaling 15/208 101/10654 9.341976474917922e-10 1.031305034533702e-8 6.792988433977713e-9 7316/84433/841/8517/1147/3551/8915/7189/3553/6714/9020/10892/4790/29108/5970 15 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-209543 p75NTR recruits signalling complexes 7/208 13/10654 1.5189158213514871e-9 1.655026459888179e-8 1.0901309722618328e-8 7316/5584/3551/4615/7189/8878/8767 7 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-622312 Inflammasomes 8/208 20/10654 1.9008008979847686e-9 2.0445794274477192e-8 1.3467212839973056e-8 351/598/834/4790/29108/5970/596/58484 8 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5688426 Deubiquitination 24/208 297/10654 3.3182155651674124e-9 3.524028935665138e-8 2.321203426666078e-8 64135/7316/5728/9099/387/1540/7706/8517/330/7128/7189/84282/8678/367/57506/7186/8737/10392/4609/23586/329/7157/8767/8314 24 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-8874081 MET activates PTK2 signaling 9/208 30/10654 3.4766116157976415e-9 3.6460964320677767e-8 2.4016067082812654e-8 1281/1301/1280/1290/1289/1302/6714/1278/1277 9 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 7/208 16/10654 9.633169604932659e-9 9.978060862393211e-8 6.572337937088558e-8 7316/23643/7099/7189/929/353376/148022 7 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 9/208 34/10654 1.1910909399661343e-8 1.218689388575106e-7 8.027249595407195e-8 64135/7316/1540/7706/7128/84282/57506/23586/9474 9 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-446652 Interleukin-1 family signaling 16/208 140/10654 1.268591862299178e-8 1.2823476776735064e-7 8.446553300026233e-8 7316/351/8517/1147/3551/4615/7189/5783/3553/834/8878/4790/10392/5599/5970/8767 16 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 7/208 17/10654 1.6106325932719157e-8 1.6087151735180204e-7 1.0596267060999446e-7 7316/23643/7099/7189/929/353376/148022 7 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-6804757 Regulation of TP53 Degradation 9/208 36/10654 2.0666921851632155e-8 2.0399467568846328e-7 1.343669841746982e-7 2475/7316/1616/9099/80196/7157/472/5515/207 9 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 14/208 108/10654 2.0970745148816527e-8 2.0458668813787286e-7 1.3475693027085282e-7 7124/6657/598/3553/3320/4609/7157/1278/7431/356/596/4170/3598/207 14 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-6806003 Regulation of TP53 Expression and Degradation 9/208 37/10654 2.6851548663874364e-8 2.5894769343667346e-7 1.7056337626780448e-7 2475/7316/1616/9099/80196/7157/472/5515/207 9 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 11/208 63/10654 3.053788912214472e-8 2.911510110622661e-7 1.9177502140102844e-7 7316/8517/1147/3551/4615/7098/11035/4790/8737/5970/148022 11 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-111465 Apoptotic cleavage of cellular proteins 9/208 38/10654 3.4594379318704865e-8 3.261200477347571e-7 2.148083872539332e-7 841/5339/4137/836/839/10134/329/7431/840 9 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 6/208 12/10654 4.318144445827943e-8 4.025470211166272e-7 2.651492203578561e-7 8794/355/7157/8797/8795/8793 6 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-75153 Apoptotic execution phase 10/208 52/10654 5.016847682703675e-8 4.6254233030641575e-7 3.0466686332208554e-7 841/5339/4137/836/839/10059/10134/329/7431/840 10 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-8875878 MET promotes cell motility 9/208 41/10654 7.0670387165488e-8 6.444832046939613e-7 4.2450747439223335e-7 1281/1301/1280/1290/1289/1302/6714/1278/1277 9 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-3000157 Laminin interactions 8/208 30/10654 7.465679535253018e-8 6.735166806534711e-7 4.4363121177225064e-7 1288/3685/1284/1286/1287/1285/1282/1294 8 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-209560 NF-kB is activated and signals survival 6/208 13/10654 7.88921832899323e-8 7.041546997899276e-7 4.638118278523455e-7 7316/3551/7189/8878/4790/5970 6 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-9020702 Interleukin-1 signaling 13/208 103/10654 9.398442559412585e-8 8.300308744575955e-7 5.467238053951919e-7 7316/351/8517/1147/3551/4615/7189/3553/8878/4790/10392/5970/8767 13 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5621481 C-type lectin receptors (CLRs) 15/208 142/10654 1.0623091833407844e-7 9.284139633572064e-7 6.115266680415699e-7 7316/84433/841/8517/1147/3551/8915/7189/3553/6714/9020/10892/4790/29108/5970 15 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 7/208 23/10654 1.8376614175636698e-7 1.5894824013772359e-6 1.0469584853184227e-6 7316/8517/7189/5609/10392/5599/8767 7 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 14/208 134/10654 3.282216538387183e-7 2.8099792609253538e-6 1.850873987812321e-6 7316/84433/8517/1147/3551/8915/7189/5594/5609/10892/4790/5599/5970/5595 14 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-202424 Downstream TCR signaling 12/208 98/10654 4.157420261426914e-7 3.5233086861991723e-6 2.3207290135556936e-6 7316/84433/5728/8517/1147/3551/8915/7189/10892/4790/5970/8767 12 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-9612973 Autophagy 13/208 119/10654 5.212358450125329e-7 4.373168739655151e-6 2.8805138803324187e-6 2475/7316/11315/8678/6714/3320/84557/8878/84971/5289/7431/9474/81631 13 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-3000170 Syndecan interactions 7/208 27/10654 6.228888462622639e-7 5.174294475386528e-6 3.4081984813724706e-6 1281/1290/1289/3685/1278/3690/1277 7 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 6/208 18/10654 7.864569233661767e-7 6.468993712786492e-6 4.260989522881762e-6 7316/23643/7099/929/353376/148022 6 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-933541 TRAF6 mediated IRF7 activation 7/208 29/10654 1.0590445038390288e-6 8.62658581282471e-6 5.682149867301892e-6 64135/7706/7189/84282/57506/7186/23586 7 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-6806834 Signaling by MET 10/208 79/10654 2.887776940384693e-6 2.3296585124834203e-5 1.5344968559736474e-5 7316/1281/1301/1280/1290/1289/1302/6714/1278/1277 10 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-202403 TCR signaling 12/208 119/10654 3.3911908552925963e-6 2.709722978657608e-5 1.784837292259261e-5 7316/84433/5728/8517/1147/3551/8915/7189/10892/4790/5970/8767 12 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-1257604 PIP3 activates AKT signaling 18/208 264/10654 3.993635588252489e-6 3.1610002439092816e-5 2.0820840951663917e-5 51564/2475/7316/5728/1956/1147/4615/7189/842/331/6714/5594/7157/5595/1107/5515/1027/207 18 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-2871837 FCERI mediated NF-kB activation 10/208 82/10654 4.075259608110735e-6 3.195460571219539e-5 2.1047823849071672e-5 7316/84433/8517/1147/3551/8915/7189/10892/4790/5970 10 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 11/208 102/10654 4.542652346776739e-6 3.52896788791267e-5 2.3244566101927755e-5 7316/8742/7124/1147/330/7132/8718/9020/7186/329/356 11 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-918233 TRAF3-dependent IRF activation pathway 5/208 14/10654 4.689216692062686e-6 3.6094062427895356e-5 2.377439655560512e-5 64135/7706/84282/57506/23586 5 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 6/208 24/10654 5.169933648704693e-6 3.872834224342176e-5 2.5509541029792896e-5 7316/8517/7189/1432/10392/8767 6 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-8940973 RUNX2 regulates osteoblast differentiation 6/208 24/10654 5.169933648704693e-6 3.872834224342176e-5 2.5509541029792896e-5 5925/6714/367/5594/5595/1277 6 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 6/208 24/10654 5.169933648704693e-6 3.872834224342176e-5 2.5509541029792896e-5 1956/5594/5595/596/1027/207 6 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-1169091 Activation of NF-kappaB in B cells 9/208 67/10654 5.559260206909891e-6 4.127627711148141e-5 2.7187811910830863e-5 7316/84433/8517/1147/3551/8915/10892/4790/5970 9 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5689880 Ub-specific processing proteases 16/208 220/10654 6.183640367041565e-6 4.550942340305151e-5 2.9976095962112848e-5 64135/7316/5728/9099/1540/8517/330/7189/8678/367/7186/8737/4609/23586/329/7157 16 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-844456 The NLRP3 inflammasome 5/208 15/10654 6.9224777648401665e-6 4.964067388633248e-5 3.269726339668095e-5 351/834/4790/29108/5970 5 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-937039 IRAK1 recruits IKK complex 5/208 15/10654 6.9224777648401665e-6 4.964067388633248e-5 3.269726339668095e-5 7316/8517/1147/3551/7189 5 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 5/208 15/10654 6.9224777648401665e-6 4.964067388633248e-5 3.269726339668095e-5 7316/8517/1147/3551/7189 5 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-1295596 Spry regulation of FGF signaling 5/208 16/10654 9.909726124926857e-6 6.9867732931207e-5 4.602039996096063e-5 7316/6714/5594/5595/5515 5 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 5/208 16/10654 9.909726124926857e-6 6.9867732931207e-5 4.602039996096063e-5 7316/8517/1147/3551/4790 5 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-1169408 ISG15 antiviral mechanism 9/208 72/10654 1.0171474831650634e-5 7.111556153129068e-5 4.684231830365424e-5 8672/7316/1982/7706/1977/1973/23586/5595/1981 9 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 14/208 182/10654 1.2668221178265635e-5 8.783997990549478e-5 5.785833943966471e-5 51564/1616/142/9994/8517/641/9971/11315/367/7428/7157/5970/1107/10210 14 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5633007 Regulation of TP53 Activity 13/208 160/10654 1.4495528267691162e-5 9.968646079174495e-5 6.566136618238015e-5 2475/7316/1616/9099/641/80196/1111/1432/7157/1107/472/5515/207 13 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-1632852 Macroautophagy 10/208 95/10654 1.544147064958716e-5 1.0532840548783437e-4 6.937759598659186e-5 2475/7316/8678/6714/84557/8878/84971/5289/9474/81631 10 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5205647 Mitophagy 6/208 29/10654 1.6817511102780722e-5 1.1378945012284699e-4 7.495070737656944e-5 7316/6714/84557/8878/9474/81631 6 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-2990846 SUMOylation 14/208 188/10654 1.83036195069888e-5 1.2285389413090882e-4 8.092126518879259e-5 51564/1616/142/9994/8517/641/9971/11315/367/7428/7157/5970/1107/10210 14 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 5/208 18/10654 1.8828357216160816e-5 1.2537295003459465e-4 8.258051410596849e-5 8742/330/9020/7186/329 5 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-2262752 Cellular responses to stress 24/208 479/10654 2.050517411533717e-5 1.3546331561234556e-4 8.922682478700385e-5 2475/7316/54205/4217/5925/1783/3309/9588/51143/367/3320/5594/1432/5609/7428/4790/1051/1410/7157/5599/5970/5595/472/1027 24 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-114452 Activation of BH3-only proteins 6/208 30/10654 2.068222868774006e-5 1.3556554585167116e-4 8.929416168637771e-5 10018/637/7157/5599/596/207 6 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 9/208 80/10654 2.4218844462659096e-5 1.5751636049744948e-4 1.0375269965643432e-4 8672/7316/1982/7706/1977/1973/23586/5595/1981 9 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-3000480 Scavenging by Class A Receptors 5/208 19/10654 2.514891092038395e-5 1.623072020169395e-4 1.0690832577491152e-4 1281/1284/1278/1282/1277 5 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-450341 Activation of the AP-1 family of transcription factors 4/208 10/10654 2.7032506753698386e-5 1.718202512602496e-4 1.1317437038031622e-4 5594/1432/5599/5595 4 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5602498 MyD88 deficiency (TLR2/4) 4/208 10/10654 2.7032506753698386e-5 1.718202512602496e-4 1.1317437038031622e-4 23643/7099/4615/929 4 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-2559583 Cellular Senescence 14/208 195/10654 2.7581624545490932e-5 1.739923533358413e-4 1.1460508813915901e-4 7316/4217/5925/5594/1432/5609/4790/1051/7157/5599/5970/5595/472/1027 14 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-9006925 Intracellular signaling by second messengers 18/208 305/10654 2.8777989730815244e-5 1.801845774936865e-4 1.1868377540202674e-4 51564/2475/7316/5728/1956/1147/4615/7189/842/331/6714/5594/7157/5595/1107/5515/1027/207 18 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-8941326 RUNX2 regulates bone development 6/208 32/10654 3.055294805281975e-5 1.8988091419493163e-4 1.2507054758464226e-4 5925/6714/367/5594/5595/1277 6 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 9/208 83/10654 3.263681961612948e-5 2.0052841838710976e-4 1.3208383370332178e-4 7316/84433/8517/1147/3551/8915/10892/4790/5970 9 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-8953897 Cellular responses to external stimuli 24/208 493/10654 3.274421134569015e-5 2.0052841838710976e-4 1.3208383370332178e-4 2475/7316/54205/4217/5925/1783/3309/9588/51143/367/3320/5594/1432/5609/7428/4790/1051/1410/7157/5599/5970/5595/472/1027 24 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5603041 IRAK4 deficiency (TLR2/4) 4/208 11/10654 4.183094932343419e-5 2.506869034454378e-4 1.6512216838197709e-4 23643/7099/4615/929 4 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-8934903 Receptor Mediated Mitophagy 4/208 11/10654 4.183094932343419e-5 2.506869034454378e-4 1.6512216838197709e-4 6714/84557/9474/81631 4 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 4/208 11/10654 4.183094932343419e-5 2.506869034454378e-4 1.6512216838197709e-4 7316/7189/7098/148022 4 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-445144 Signal transduction by L1 5/208 21/10654 4.26312527440574e-5 2.536710712926536e-4 1.67087776712431e-4 1956/3685/5594/5595/3690 5 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5205685 Pink/Parkin Mediated Mitophagy 5/208 22/10654 5.4298965321311744e-5 3.2082275989141234e-4 2.113191756389078e-4 7316/84557/8878/9474/81631 5 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-8848021 Signaling by PTK6 7/208 54/10654 7.946547090969394e-5 4.6299673675856407e-4 3.049661712543079e-4 7316/387/120892/1956/10657/1027/207 7 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 7/208 54/10654 7.946547090969394e-5 4.6299673675856407e-4 3.049661712543079e-4 7316/387/120892/1956/10657/1027/207 7 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 5/208 25/10654 1.044481751932931e-4 6.043587516356753e-4 3.980783446568339e-4 2475/1147/842/1027/207 5 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-198323 AKT phosphorylates targets in the cytosol 4/208 14/10654 1.211691079388874e-4 6.963074079501817e-4 4.58642982465147e-4 1147/842/1027/207 4 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-9009391 Extra-nuclear estrogen signaling 8/208 77/10654 1.2226589540689653e-4 6.978305186828992e-4 4.5964622333419746e-4 1956/6714/3320/5594/5595/596/1027/207 8 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-1236975 Antigen processing-Cross presentation 9/208 99/10654 1.3133529648108342e-4 7.445291469434391e-4 4.904056234179857e-4 7316/23643/7099/8517/1147/3685/3551/4615/929 9 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-2173782 Binding and Uptake of Ligands by Scavenger Receptors 6/208 42/10654 1.5033449478957022e-4 8.465143699895934e-4 5.575811357437256e-4 1281/1284/3320/1278/1282/1277 6 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-166520 Signaling by NTRKs 9/208 101/10654 1.5320992303257427e-4 8.569541694955321e-4 5.64457611172642e-4 387/5900/581/6714/5594/1432/5595/5515/1213 9 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-187037 Signaling by NTRK1 (TRKA) 8/208 80/10654 1.6022253252096917e-4 8.902430780469745e-4 5.863843121192668e-4 387/5900/6714/5594/1432/5595/5515/1213 8 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-1236974 ER-Phagosome pathway 8/208 83/10654 2.0739207406489534e-4 0.0011447496719766263 7.540224299450835e-4 7316/23643/7099/8517/1147/3551/4615/929 8 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-205043 NRIF signals cell death from the nucleus 4/208 16/10654 2.13647874082473e-4 0.0011715723291189205 7.716899476663111e-4 7316/7189/8878/5599 4 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5654732 Negative regulation of FGFR3 signaling 5/208 29/10654 2.190964487391971e-4 0.0011936488343648466 7.862312753798938e-4 7316/6714/5594/5595/5515 5 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-199418 Negative regulation of the PI3K/AKT network 9/208 110/10654 2.929083611459857e-4 0.0015854846129127872 0.001044325226496723 5728/1956/4615/7189/6714/5594/5595/5515/207 9 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 5/208 31/10654 3.0369228916883427e-4 0.0016229161185519233 0.0010689805686465838 5594/1432/5599/5595/5515 5 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5654733 Negative regulation of FGFR4 signaling 5/208 31/10654 3.0369228916883427e-4 0.0016229161185519233 0.0010689805686465838 7316/6714/5594/5595/5515 5 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 9/208 112/10654 3.351754782607689e-4 0.0017798242168404119 0.0011723326188334687 7316/84433/8517/1147/3551/8915/10892/4790/5970 9 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-1227986 Signaling by ERBB2 6/208 50/10654 4.000194943962828e-4 0.002110794690556486 0.001390335879232363 7316/387/1956/6714/3320/207 6 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-6807070 PTEN Regulation 10/208 140/10654 4.0965166433154293e-4 0.0021284505328763802 0.001401965409648202 51564/2475/7316/5728/331/5594/7157/5595/1107/207 10 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-2559585 Oncogene Induced Senescence 5/208 33/10654 4.1097614579973016e-4 0.0021284505328763802 0.001401965409648202 7316/5925/5594/7157/5595 5 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5654726 Negative regulation of FGFR1 signaling 5/208 33/10654 4.1097614579973016e-4 0.0021284505328763802 0.001401965409648202 7316/6714/5594/5595/5515 5 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5663202 Diseases of signal transduction 18/208 377/10654 4.1804999669034455e-4 0.0021518033571975405 0.0014173474217786949 51564/2475/7316/5728/1956/10018/11160/1147/842/6714/3320/5594/4609/5595/5515/3690/1027/207 18 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-187687 Signalling to ERKs 5/208 34/10654 4.742664337794109e-4 0.002411572957217732 0.001588452170553051 5900/6714/5594/1432/5595 5 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5654727 Negative regulation of FGFR2 signaling 5/208 34/10654 4.742664337794109e-4 0.002411572957217732 0.001588452170553051 7316/6714/5594/5595/5515 5 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-373760 L1CAM interactions 9/208 119/10654 5.247290359815956e-4 0.0026520943445093896 0.0017468785281568654 1956/4478/3685/6714/5594/7430/5595/3690/1213 9 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 4/208 20/10654 5.349439028787635e-4 0.00268753254200768 0.00177022092033628 581/637/7157/472 4 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-8878166 Transcriptional regulation by RUNX2 9/208 121/10654 5.926766364214782e-4 0.0029598553449858346 0.0019495941987548624 7316/5925/581/6714/367/5594/5595/207/1277 9 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-204998 Cell death signalling via NRAGE, NRIF and NADE 7/208 76/10654 6.83026309935404e-4 0.0033908820948864143 0.0022335024149242426 7316/10018/836/7189/835/8878/5599 7 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-4420097 VEGFA-VEGFR2 Pathway 8/208 99/10654 6.899875676930967e-4 0.003405291584085342 0.0022429936411075897 2475/387/3685/6714/3320/1432/3690/207 8 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-198753 ERK/MAPK targets 4/208 22/10654 7.833339975381121e-4 0.0038210303717120704 0.0025168319994339585 5594/1432/5595/5515 4 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-9613829 Chaperone Mediated Autophagy 4/208 22/10654 7.833339975381121e-4 0.0038210303717120704 0.0025168319994339585 7316/11315/3320/7431 4 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-2219528 PI3K/AKT Signaling in Cancer 8/208 101/10654 7.879195755472782e-4 0.003821182218983621 0.002516932018024467 2475/5728/1956/1147/842/6714/1027/207 8 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 8/208 103/10654 8.967341535761871e-4 0.004323907786496673 0.002848066730958852 1956/4615/7189/6714/5594/5595/5515/207 8 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-76009 Platelet Aggregation (Plug Formation) 5/208 39/10654 9.067483312601497e-4 0.004347210571012947 0.0028634157829267883 6714/1278/3690/207/1277 5 Rachiplusia_ou_multiple_nucleopolyhedrovirus R-HSA-5654741 Signaling by FGFR3 5/208 40/10654 0.0010200508488634426 0.004862628762479706 0.003202910859170498 7316/6714/5594/5595/5515 5 Reovirus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 282/2430 309/10654 1.6225925032109598e-151 2.1677835842898423e-148 1.1750985707464635e-148 8454/9354/57154/5718/197131/23352/5689/26224/8945/10293/51088/140460/5684/79754/6737/8065/64410/127544/114088/11065/285231/221687/9666/84937/57531/142678/55070/5682/84708/246184/146330/55819/51320/93611/7319/54850/142686/8916/26046/79791/151636/5700/7321/5707/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/8697/7320/5690/26235/10477/9817/10193/148581/9039/223082/92912/154881/5717/140739/25897/6500/6478/150726/390594/10533/81559/144699/143471/5706/140462/5705/26259/57674/51130/10197/53339/154214/7336/200845/79876/26263/64750/51619/6477/9690/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/10213/5709/9604/9978/22888/23304/7317/80196/114907/140456/64718/54926/4008/7335/84861/11059/55236/84085/55958/54620/4734/84078/7337/26272/84676/140691/27252/51444/7704/8651/3093/26118/222235/51433/9861/25831/7322/5715/64219/10489/23327/9867/26249/140458/55905/5701/5688/55336/5687/26270/143279/51465/63893/89122/6502/23291/118424/5685/10616/5683/5708/27246/5692/5686/89910/55521/25898/9903/201456/55294/26190/55008/7328/79654/5710/10422/84727/135892/7428/5702/22954/8453/401036/83737/51529/9040/90933/140461/7324/63891/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/5704/6233/90135/56658/9870/9520/51434/6468/26267/142685/25847/90025/7327/10425/25793/51343/7311/26091/23295/6047/84541/7318/23194/51666/90293/131405/55175/55284/868/54461/9320/80204/136371/26232/29882/57520/26234/127247/27338/7334/92591/5930/11275/55182/5694/84961/4591/23014/29116/26268/92369/115290/7332/90678/51725/140459/5693/997/23608/51676/55585/64320/51132/84261/7325/57542/9820/55658/7314/996/10324/283807/899 282 Reovirus R-HSA-983169 Class I MHC mediated antigen processing & presentation 295/2430 371/10654 1.3406970319363495e-123 8.955856173334815e-121 4.854734515643202e-121 8454/9354/57154/5718/197131/23352/5689/26224/8945/10293/51088/140460/5684/79754/6737/8065/64410/127544/114088/11065/285231/221687/9666/10952/84937/57531/142678/55070/5682/84708/246184/146330/55819/51320/93611/7319/54850/142686/8916/26046/79791/151636/5700/3107/7321/5707/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/10484/8697/7320/5690/26235/10477/9817/10193/148581/55176/9039/223082/92912/154881/5717/140739/821/25897/6500/6478/150726/390594/811/10533/81559/144699/143471/5706/140462/5705/26259/57674/51130/10197/53339/154214/7336/200845/79876/26263/64750/51619/6477/9690/9554/23480/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/10213/5709/9604/9978/22888/23304/29927/7317/80196/114907/140456/64718/54926/4008/7335/84861/11059/55236/84085/55958/54620/4734/84078/7337/26272/84676/140691/27252/51444/7704/8651/3093/26118/222235/51433/9861/25831/7322/5715/64219/10489/23327/9867/26249/140458/55905/5701/5688/55336/5687/26270/143279/51465/63893/89122/6502/23291/118424/5685/10616/5683/3309/5708/27246/5692/5686/89910/55521/25898/9903/201456/55294/26190/55008/2923/7328/79654/5710/10422/84727/135892/7428/5702/22954/8453/401036/83737/51529/9040/90933/140461/7324/63891/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/5704/6233/90135/56658/9870/9520/51434/6468/26267/142685/25847/90025/7327/10425/25793/51343/7311/26091/23295/6047/84541/7318/23194/51666/90293/131405/55175/55284/868/54461/9320/80204/136371/26232/29882/57520/26234/6396/127247/27338/7334/92591/5930/11275/55182/5694/84961/4591/23014/29116/26268/92369/115290/7332/90678/51725/140459/3105/5693/997/23608/51676/55585/64320/51132/84261/7325/57542/9820/55658/7314/996/10324/283807/899 295 Reovirus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 221/2430 244/10654 2.0877385353652062e-116 9.297395610826385e-114 5.039874078355304e-114 10450/7536/10921/8449/23165/22827/23451/7919/53981/4928/2963/6635/81929/5434/5440/5903/6633/220988/55599/6432/8683/51691/6431/10084/6430/6632/51340/10283/6627/7175/24148/6936/154007/100534599/10946/9631/7884/83443/27339/84271/11051/9129/55696/23350/5430/79869/85437/4904/5436/9879/10081/51639/51585/10523/6428/11325/9128/57703/27258/3184/8106/25804/10212/51690/29894/27238/9589/55749/11017/51503/3178/6637/199746/23450/348995/79023/57122/5441/3183/5438/85313/79622/5431/9092/55110/54883/5093/22794/81608/5435/10594/4686/9785/8189/23398/6625/5433/10713/51645/11338/1655/9343/55954/3185/4116/3190/1477/10978/9416/65109/6626/56339/84321/11157/5546/22826/7307/285755/6429/1478/10772/24144/57819/23279/10181/9688/8233/79902/2962/10898/22938/988/10236/9984/5437/10250/6629/4670/23020/10569/23225/26097/23658/10189/6434/51362/9295/10465/84844/6631/10482/10949/51692/55660/3181/5439/10421/11193/51729/1660/25949/23283/8086/9939/11066/2521/1977/3191/10285/9410/6638/57794/57721/9877/27316/6636/3187/1993/1665/10286/23524/56949/53938/6634/10914/5094/51593/8021/9775/3192/57187/9716/84248/6396/129401/8896/6427/3312/8175/5356/6426/84950/57461/3188/84991/10907/10291/5432/55746/22916/56259/5725/1479/26121/11100/8480/10992/55339/10262/6628/1994 221 Reovirus R-HSA-72172 mRNA Splicing 187/2430 191/10654 6.301108639622456e-116 2.1045702856339003e-113 1.1408323010684867e-113 10450/7536/10921/8449/22827/23451/53981/2963/6635/5434/5440/6633/220988/55599/6432/8683/51691/6431/10084/6430/6632/51340/10283/6627/24148/6936/154007/100534599/10946/83443/27339/11051/9129/55696/23350/5430/79869/85437/4904/5436/9879/10081/51639/51585/10523/6428/11325/9128/57703/27258/3184/8106/25804/51690/29894/27238/55749/11017/51503/3178/6637/199746/23450/5441/3183/5438/85313/79622/5431/9092/55110/54883/5093/22794/81608/5435/10594/4686/9785/8189/23398/6625/5433/10713/51645/11338/1655/9343/55954/3185/4116/3190/1477/10978/9416/65109/6626/11157/5546/22826/7307/285755/6429/1478/10772/24144/57819/10181/8233/2962/10898/22938/988/10236/5437/10250/6629/4670/23020/10569/23658/10189/6434/51362/9295/10465/84844/6631/10949/51692/55660/3181/5439/10421/11193/51729/1660/25949/23283/9939/11066/2521/3191/10285/9410/6638/57794/27316/6636/3187/1993/1665/10286/23524/56949/53938/6634/10914/5094/51593/9775/3192/9716/8896/6427/3312/8175/5356/6426/84950/57461/3188/84991/10907/10291/5432/22916/56259/5725/1479/26121/11100/10992/55339/10262/6628/1994 187 Reovirus R-HSA-72163 mRNA Splicing - Major Pathway 179/2430 183/10654 1.174231079443372e-110 3.1375454442726896e-108 1.700781016120084e-108 10450/7536/10921/8449/22827/23451/53981/2963/6635/5434/5440/6633/220988/6432/8683/51691/6431/10084/6430/6632/51340/10283/6627/24148/6936/100534599/10946/83443/27339/11051/9129/55696/23350/5430/79869/4904/5436/9879/51639/51585/10523/6428/11325/9128/57703/27258/3184/8106/25804/51690/29894/27238/55749/11017/51503/3178/6637/199746/23450/5441/3183/5438/85313/5431/9092/55110/54883/5093/22794/81608/5435/10594/4686/9785/8189/23398/6625/5433/10713/51645/11338/1655/9343/3185/4116/3190/1477/10978/9416/65109/6626/11157/5546/22826/7307/285755/6429/1478/10772/24144/57819/10181/2962/10898/22938/988/10236/5437/10250/6629/4670/23020/10569/23658/10189/6434/51362/9295/10465/84844/6631/10949/51692/55660/3181/5439/10421/11193/51729/1660/25949/23283/9939/2521/3191/10285/9410/6638/57794/27316/6636/3187/1993/1665/10286/23524/56949/53938/6634/10914/5094/51593/9775/3192/9716/8896/6427/3312/8175/5356/6426/84950/57461/3188/84991/10907/10291/5432/22916/56259/5725/1479/26121/11100/10992/55339/10262/6628/1994 179 Reovirus R-HSA-68877 Mitotic Prometaphase 188/2430 200/10654 2.2545928817619506e-106 5.020226816723276e-104 2.7213331625477574e-104 114791/10844/115106/220134/4926/5905/55839/11130/22995/84617/4928/55559/79682/81929/5903/10403/79861/54908/440145/6249/55143/11258/64151/22981/55055/25936/5525/9735/8636/7531/10142/80776/1459/1783/1058/11190/991/401541/203068/79019/5526/54801/51807/7532/55125/1454/348235/80152/10382/9212/1063/347688/8379/95681/3619/79172/10274/121441/1460/147841/23244/7277/348995/23421/79441/55920/79023/9133/10381/57122/79980/64105/10735/5116/7278/6232/332/23047/112714/1780/9814/653784/10051/5885/23122/5528/5048/1781/23354/80321/891/5501/57405/8655/4085/9738/1457/983/1639/55722/4957/23279/55166/10121/79902/9702/5566/3796/79959/54821/5519/84131/9183/81565/2491/1062/699/7846/7840/113457/7283/347733/3320/22919/80097/1060/91687/79003/8243/9126/10376/10426/5529/22994/11064/51143/9918/10540/81027/10733/85378/1069/83540/4751/11004/5577/5527/27175/80254/701/7514/9184/54930/5518/10383/55835/54820/5347/113130/57551/29922/84790/84643/6396/9662/80184/55142/23332/1453/22897/25909/27229/64946/9793/10726/5108/81930/55746/8481/140735/93323/10592/7280/10806/55755/5515/1778/5516 188 Reovirus R-HSA-68886 M Phase 264/2430 395/10654 6.416756581101866e-81 1.2246838274788704e-78 6.63868951548584e-79 114791/10844/4000/115106/5718/23165/220134/4926/5689/5905/55839/11130/22995/84617/4928/55559/79682/81929/5684/5903/10403/79861/11065/54908/440145/7175/6249/55143/11258/5682/64151/22981/9631/246184/55055/25936/5525/9735/8636/7531/10142/80776/1459/1783/1058/5700/11190/7321/5707/991/91754/401541/203068/79019/5526/54801/51807/7532/55125/1454/348235/80152/8697/5690/10382/9212/5594/1063/347688/8379/95681/5717/3619/79172/10274/5861/5925/121441/1460/10783/147841/23244/7277/348995/23421/79441/143471/55920/79023/5706/9133/10381/57122/5705/79980/64105/10735/5116/10197/7278/6232/332/7443/23047/112714/1780/8881/9814/653784/10051/5885/23122/5528/5048/1781/23354/7316/10213/5709/80321/891/5501/57405/8655/4085/9738/1457/983/1639/55722/4957/23279/9688/55166/10121/51433/9861/79902/9702/5566/3796/5715/79959/54821/5519/84131/9183/81565/5701/2491/5688/10112/1062/699/5687/7846/23225/7840/113457/5685/7283/5683/7444/347733/5708/3320/22919/5692/5686/80097/1060/91687/119504/79003/8243/9126/10376/10426/5529/5710/22994/11064/51143/9918/5702/10540/5520/81027/10733/51529/85378/1069/8086/7324/2010/83540/4001/64682/29945/10393/79648/4751/11004/5577/5704/6233/9700/5527/23133/51434/27175/80254/701/7514/7311/9184/54930/5518/25906/55844/10383/55835/54820/5347/113130/57551/29922/84790/8021/84643/29882/6396/129401/9662/80184/55142/5694/23332/1453/22897/25909/27229/64946/9793/10726/5108/81930/55746/8481/7112/5693/140735/93323/10592/7280/10806/55755/29781/8480/7314/996/5515/1778/5516 264 Reovirus R-HSA-68882 Mitotic Anaphase 171/2430 201/10654 5.080976491205389e-80 8.485230740313e-78 4.59962082361751e-78 4000/5718/220134/5689/5905/55839/11130/84617/4928/79682/81929/5684/5903/10403/79861/11065/54908/6249/55143/5682/246184/55055/25936/5525/9735/80776/1783/1058/5700/7321/5707/991/401541/79019/5526/51807/348235/80152/8697/5690/10382/9212/1063/347688/8379/5717/3619/79172/10274/147841/23244/7277/348995/23421/143471/55920/79023/5706/10381/57122/5705/79980/64105/10735/10197/7278/6232/332/7443/23047/112714/1780/8881/5885/23122/5528/5048/1781/7316/10213/5709/5501/57405/8655/4085/23279/55166/51433/9861/79902/3796/5715/54821/5519/9183/81565/5701/2491/5688/1062/699/5687/7846/113457/5685/5683/7444/347733/5708/22919/5692/5686/1060/91687/119504/79003/8243/9126/10376/5529/5710/51143/5702/5520/81027/51529/7324/2010/83540/4001/64682/29945/10393/11004/5704/6233/9700/5527/51434/701/7514/7311/9184/5518/25906/10383/54820/5347/113130/57551/84790/84643/29882/6396/5694/23332/25909/64946/9793/10726/81930/55746/7112/5693/140735/7280/7314/996/5515/1778/5516 171 Reovirus R-HSA-2555396 Mitotic Metaphase and Anaphase 171/2430 202/10654 2.599708065565045e-79 3.859122195105445e-77 2.0919288293669602e-77 4000/5718/220134/5689/5905/55839/11130/84617/4928/79682/81929/5684/5903/10403/79861/11065/54908/6249/55143/5682/246184/55055/25936/5525/9735/80776/1783/1058/5700/7321/5707/991/401541/79019/5526/51807/348235/80152/8697/5690/10382/9212/1063/347688/8379/5717/3619/79172/10274/147841/23244/7277/348995/23421/143471/55920/79023/5706/10381/57122/5705/79980/64105/10735/10197/7278/6232/332/7443/23047/112714/1780/8881/5885/23122/5528/5048/1781/7316/10213/5709/5501/57405/8655/4085/23279/55166/51433/9861/79902/3796/5715/54821/5519/9183/81565/5701/2491/5688/1062/699/5687/7846/113457/5685/5683/7444/347733/5708/22919/5692/5686/1060/91687/119504/79003/8243/9126/10376/5529/5710/51143/5702/5520/81027/51529/7324/2010/83540/4001/64682/29945/10393/11004/5704/6233/9700/5527/51434/701/7514/7311/9184/5518/25906/10383/54820/5347/113130/57551/84790/84643/29882/6396/5694/23332/25909/64946/9793/10726/81930/55746/7112/5693/140735/7280/7314/996/5515/1778/5516 171 Reovirus R-HSA-2467813 Separation of Sister Chromatids 164/2430 190/10654 9.157392060434208e-79 1.2234275792740101e-76 6.631879723767089e-77 5718/220134/5689/5905/55839/11130/84617/4928/79682/81929/5684/5903/10403/79861/11065/54908/6249/55143/5682/246184/55055/25936/5525/9735/80776/1783/1058/5700/7321/5707/991/401541/79019/5526/51807/348235/80152/8697/5690/10382/9212/1063/347688/8379/5717/3619/79172/10274/147841/23244/7277/348995/23421/143471/55920/79023/5706/10381/57122/5705/79980/64105/10735/10197/7278/6232/332/23047/112714/1780/8881/5885/23122/5528/5048/1781/7316/10213/5709/5501/57405/8655/4085/23279/55166/51433/9861/79902/3796/5715/54821/5519/9183/81565/5701/2491/5688/1062/699/5687/7846/113457/5685/5683/347733/5708/22919/5692/5686/1060/91687/119504/79003/8243/9126/10376/5529/5710/51143/5702/81027/51529/7324/83540/64682/29945/10393/11004/5704/6233/9700/5527/51434/701/7514/7311/9184/5518/25906/10383/54820/5347/113130/57551/84790/84643/29882/6396/5694/23332/25909/64946/9793/10726/81930/55746/5693/140735/7280/7314/996/5515/1778/5516 164 Reovirus R-HSA-8868773 rRNA processing in the nucleus and cytosol 162/2430 195/10654 1.188056190278909e-72 1.4429482456478387e-70 7.821843625951095e-71 84946/6158/5393/9136/6138/6144/2091/6203/51504/55127/6227/23246/9349/55813/4736/8602/6206/6194/57418/6234/22803/6191/54913/6166/6128/51121/6132/10557/6147/6159/25879/6129/6217/55226/10436/27292/8780/6222/9277/1454/81887/6176/84128/6152/6136/56902/10528/84135/27340/27043/6125/55623/57050/4839/6224/6146/51065/6154/6141/88745/51602/6202/6123/51096/6232/90459/134430/6134/6169/6160/55272/55781/6164/6155/92856/6175/6218/65083/9724/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/11102/6142/6167/28987/6204/1736/11056/6228/23521/116832/23481/54555/9790/51077/140801/6156/117246/10171/6235/5822/55720/10199/6143/6181/6124/6207/10969/6139/10556/705/79159/6233/25926/23160/7311/6223/25873/83732/27341/26168/3921/6188/6189/10607/10799/11103/26354/6135/6201/51388/6161/54881/1453/51202/9045/57647/6187/4691/6168/6208/6157/6137/6170/10885/22984/10813/200916/79050/6122/6133/79897/9188/6230 162 Reovirus R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 156/2430 185/10654 7.729909386274644e-72 8.60596578338577e-70 4.665068120839434e-70 84946/6158/5393/9136/6138/6144/2091/6203/55127/6227/23246/9349/55813/4736/8602/6206/6194/57418/6234/22803/6191/54913/6166/6128/51121/6132/10557/6147/6159/25879/6129/6217/10436/8780/6222/9277/1454/81887/6176/84128/6152/6136/56902/10528/84135/27340/27043/6125/57050/6224/6146/51065/6154/6141/88745/51602/6202/6123/51096/6232/90459/134430/6134/6169/6160/55272/55781/6164/6155/92856/6175/6218/65083/9724/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/11102/6142/6167/28987/6204/11056/6228/23521/116832/23481/54555/9790/51077/140801/6156/117246/10171/6235/5822/55720/10199/6143/6181/6124/6207/10969/6139/10556/705/79159/6233/25926/23160/7311/6223/25873/83732/27341/26168/3921/6188/6189/10607/10799/11103/26354/6135/6201/51388/6161/54881/1453/51202/9045/57647/6187/4691/6168/6208/6157/6137/6170/10885/22984/10813/200916/79050/6122/6133/79897/9188/6230 156 Reovirus R-HSA-168254 Influenza Infection 137/2430 155/10654 1.0203297560437563e-68 1.0485850415957373e-66 5.684104228000844e-67 6158/23165/3303/6138/4928/6144/2963/3837/3838/81929/6203/5434/5440/5903/6227/9349/4736/6206/6194/6234/6191/7175/6166/6128/51121/6132/9631/6147/6159/6129/6217/3843/5430/6222/5436/6176/6152/6136/8106/6125/821/811/6224/6146/348995/51065/6154/6141/9636/6202/79023/6123/57122/5441/6232/5438/6134/6169/5431/6160/6164/5435/6155/6175/293/5433/6218/5611/6209/6193/6173/23279/6210/6231/9688/6229/11224/6205/6165/79902/6130/2962/6142/10898/6167/3840/6204/6228/5437/23521/116832/23225/3320/140801/6156/6235/6143/6181/5439/6124/5901/6207/8086/3836/6139/6233/7514/7311/6223/25873/1213/5610/3921/6188/6189/8021/7040/6396/6135/6201/129401/6161/3304/9045/6187/5432/55746/6168/6208/6157/6137/6170/200916/8480/6122/6133/6230 137 Reovirus R-HSA-927802 Nonsense-Mediated Decay (NMD) 112/2430 115/10654 2.016772448614188e-68 1.79627199423237e-66 9.73711890980043e-67 10921/6158/9887/6138/6144/6203/6227/9349/4736/6206/6194/2107/6234/6191/6166/6128/51121/6132/6147/6159/6129/56006/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/55629/6232/26019/2935/6134/6169/6160/55110/22794/6164/4686/6155/6175/6218/4116/65109/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/55181/55802/1981/140801/6156/6235/6143/6181/6124/5520/6207/9939/6139/6233/23381/7311/6223/25873/5518/3921/6188/6189/23293/9775/23049/6135/6201/23708/6161/9045/5976/6187/65110/6168/22916/6208/6157/6137/6170/200916/6122/6133/5515/6230 112 Reovirus R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 112/2430 115/10654 2.016772448614188e-68 1.79627199423237e-66 9.73711890980043e-67 10921/6158/9887/6138/6144/6203/6227/9349/4736/6206/6194/2107/6234/6191/6166/6128/51121/6132/6147/6159/6129/56006/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/55629/6232/26019/2935/6134/6169/6160/55110/22794/6164/4686/6155/6175/6218/4116/65109/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/55181/55802/1981/140801/6156/6235/6143/6181/6124/5520/6207/9939/6139/6233/23381/7311/6223/25873/5518/3921/6188/6189/23293/9775/23049/6135/6201/23708/6161/9045/5976/6187/65110/6168/22916/6208/6157/6137/6170/200916/6122/6133/5515/6230 112 Reovirus R-HSA-72312 rRNA processing 163/2430 205/10654 1.1533927019825438e-67 9.630829061554241e-66 5.220619598447304e-66 84946/6158/5393/9136/6138/6144/2091/6203/51504/55127/6227/23246/9349/55813/4736/8602/6206/6194/57418/6234/22803/6191/54913/6166/6128/51121/6132/10557/6147/6159/25879/6129/6217/3028/55226/10436/27292/8780/6222/9277/1454/81887/6176/84128/6152/6136/56902/10528/84135/27340/27043/6125/55623/57050/4839/6224/6146/51065/6154/6141/88745/51602/6202/6123/51096/6232/90459/134430/6134/6169/6160/55272/55781/6164/6155/92856/6175/6218/65083/9724/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/11102/6142/6167/28987/6204/1736/11056/6228/23521/116832/23481/54555/9790/51077/140801/6156/117246/10171/6235/5822/55720/10199/6143/6181/6124/6207/10969/6139/10556/705/79159/6233/25926/23160/7311/6223/25873/83732/27341/26168/3921/6188/6189/10607/10799/11103/26354/6135/6201/51388/6161/54881/1453/51202/9045/57647/6187/4691/6168/6208/6157/6137/6170/10885/22984/10813/200916/79050/6122/6133/79897/9188/6230 163 Reovirus R-HSA-69275 G2/M Transition 158/2430 196/10654 3.4358274595664984e-67 2.7001561682240248e-65 1.4636837722487621e-65 114791/10844/8454/115106/5718/1017/5689/22822/8945/22995/84617/55559/5684/79861/440145/11258/5682/22981/8636/7531/51512/10142/5700/11190/5707/203068/54801/51807/7532/84962/55125/1454/22974/5690/10382/3161/1063/347688/95681/5717/6500/121441/7277/79441/143471/5706/9133/10381/5705/5116/10197/7278/112714/9814/653784/5048/1781/23354/7316/10213/728642/5709/80321/9978/891/8655/9738/983/1026/1639/6790/55722/4957/10121/9861/9702/5566/5715/79959/5519/84131/5928/5701/5688/5687/23291/7846/7840/113457/5685/7283/5683/347733/5708/3320/22919/5692/984/5686/80097/2033/10376/10426/5710/22994/11064/5702/10540/5520/7157/81027/10733/8900/85378/79866/1069/4751/5577/5704/6233/3326/27175/80254/7514/7311/54930/23194/5518/10133/10383/55835/54820/5347/29922/84790/9662/80184/55142/5694/23332/1453/22897/7465/27229/9793/4218/5108/1022/8481/5693/93323/7280/10806/55755/7314/5515/1778/5516 158 Reovirus R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 109/2430 112/10654 1.7465628097684215e-66 1.2963377299170064e-64 7.027106509477625e-65 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6147/6159/8666/6129/6217/6222/1983/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 109 Reovirus R-HSA-168255 Influenza Life Cycle 129/2430 144/10654 2.3266839114455858e-66 1.6360261608901593e-64 8.868468316202565e-65 6158/23165/3303/6138/4928/6144/2963/3837/81929/6203/5434/5440/5903/6227/9349/4736/6206/6194/6234/6191/7175/6166/6128/51121/6132/9631/6147/6159/6129/6217/3843/5430/6222/5436/6176/6152/6136/6125/821/811/6224/6146/348995/51065/6154/6141/6202/79023/6123/57122/5441/6232/5438/6134/6169/5431/6160/6164/5435/6155/6175/5433/6218/5611/6209/6193/6173/23279/6210/6231/9688/6229/11224/6205/6165/79902/6130/2962/6142/6167/6204/6228/5437/23521/116832/23225/3320/140801/6156/6235/6143/6181/5439/6124/5901/6207/8086/3836/6139/6233/7514/7311/6223/25873/1213/3921/6188/6189/8021/6396/6135/6201/129401/6161/3304/9045/6187/5432/55746/6168/6208/6157/6137/6170/200916/8480/6122/6133/6230 129 Reovirus R-HSA-453274 Mitotic G2-G2/M phases 158/2430 198/10654 5.283264376250791e-66 3.5292206033355285e-64 1.9130978372950233e-64 114791/10844/8454/115106/5718/1017/5689/22822/8945/22995/84617/55559/5684/79861/440145/11258/5682/22981/8636/7531/51512/10142/5700/11190/5707/203068/54801/51807/7532/84962/55125/1454/22974/5690/10382/3161/1063/347688/95681/5717/6500/121441/7277/79441/143471/5706/9133/10381/5705/5116/10197/7278/112714/9814/653784/5048/1781/23354/7316/10213/728642/5709/80321/9978/891/8655/9738/983/1026/1639/6790/55722/4957/10121/9861/9702/5566/5715/79959/5519/84131/5928/5701/5688/5687/23291/7846/7840/113457/5685/7283/5683/347733/5708/3320/22919/5692/984/5686/80097/2033/10376/10426/5710/22994/11064/5702/10540/5520/7157/81027/10733/8900/85378/79866/1069/4751/5577/5704/6233/3326/27175/80254/7514/7311/54930/23194/5518/10133/10383/55835/54820/5347/29922/84790/9662/80184/55142/5694/23332/1453/22897/7465/27229/9793/4218/5108/1022/8481/5693/93323/7280/10806/55755/7314/5515/1778/5516 158 Reovirus R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 108/2430 111/10654 7.718392878360135e-66 4.910368040709115e-64 2.661781604166302e-64 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6147/6159/8666/6129/6217/6222/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968/6230 108 Reovirus R-HSA-8951664 Neddylation 175/2430 234/10654 3.005232763271336e-65 1.8249958962411387e-63 9.892823641773584e-64 8454/5718/5689/26224/54165/8945/51088/140460/5684/79754/8065/64410/285231/11091/23363/5682/23038/146330/80344/25879/93611/54850/142686/79791/5700/7321/5707/51665/9616/122769/9021/4738/5690/26235/9817/9039/154881/5717/140739/5929/6500/5931/150726/3091/390594/144699/143471/5706/140462/5705/26259/51130/10197/53339/200845/332/26263/8452/8450/7323/9306/10517/89890/142689/7316/10213/5709/9978/50717/114907/140456/4008/84861/84085/55958/54620/84078/79016/26272/27252/7704/1643/26118/222235/10980/9861/7322/5715/10489/26249/140458/5701/5688/55336/5687/26270/1161/6502/7347/23291/5685/5683/55832/5708/1642/5692/23113/5686/9903/201456/55294/26190/79269/10238/5710/84727/10987/7428/5702/8453/401036/9040/140461/79176/80176/8139/126433/5704/6233/26043/90135/6468/26267/26094/142685/25793/7311/84541/23194/83987/51666/90293/55175/8533/54461/80204/136371/26232/8835/26234/127247/8883/92591/11275/5694/84961/23014/8816/26268/92369/115290/51725/140459/5693/51676/84261/150684/57542/9820/7314/51514/10324/8451/283807/899 175 Reovirus R-HSA-2500257 Resolution of Sister Chromatid Cohesion 117/2430 126/10654 1.5805045816535203e-64 9.180670091691753e-63 4.976600238799184e-63 220134/5905/55839/11130/84617/4928/79682/81929/5903/10403/79861/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/401541/79019/5526/51807/348235/80152/10382/9212/1063/347688/8379/3619/79172/10274/147841/23244/7277/348995/23421/55920/79023/9133/10381/57122/79980/64105/10735/7278/6232/332/23047/112714/1780/5885/23122/5528/5048/1781/891/5501/57405/8655/4085/983/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/7846/113457/347733/22919/1060/91687/79003/8243/9126/10376/5529/51143/81027/83540/11004/5527/701/7514/9184/5518/10383/54820/5347/113130/57551/84790/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/7280/5515/1778/5516 117 Reovirus R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 108/2430 112/10654 1.689578047303369e-64 9.405317796655421e-63 5.098375862038236e-63 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/10952/51121/6132/6147/6159/6129/6217/6222/1650/6176/6152/6136/55176/6125/6727/6224/6146/51065/6154/6141/6184/6202/6123/6232/58477/6134/6747/6169/23480/6160/6731/6164/6155/6748/6175/6218/29927/6728/60559/6746/6209/6193/6729/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/28972/140801/6156/6235/6143/6181/6124/6185/6207/6139/6745/6726/6233/23471/7311/6223/25873/6730/3921/6188/6189/9789/6135/6201/6161/90701/9045/6187/23478/6168/6208/6157/6137/6170/200916/6122/6133/6230 108 Reovirus R-HSA-72613 Eukaryotic Translation Initiation 112/2430 119/10654 1.711047598431631e-63 8.792152275017918e-62 4.76599493004438e-62 6158/8669/6138/6144/6203/6227/9349/4736/6206/8891/6194/1965/6234/27335/6191/6166/6128/51121/6132/6147/6159/8666/6129/6217/6222/1983/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/8892/1974/200916/6122/6133/1968/6230 112 Reovirus R-HSA-72737 Cap-dependent Translation Initiation 112/2430 119/10654 1.711047598431631e-63 8.792152275017918e-62 4.76599493004438e-62 6158/8669/6138/6144/6203/6227/9349/4736/6206/8891/6194/1965/6234/27335/6191/6166/6128/51121/6132/6147/6159/8666/6129/6217/6222/1983/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/26986/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/8892/1974/200916/6122/6133/1968/6230 112 Reovirus R-HSA-168273 Influenza Viral RNA Transcription and Replication 120/2430 134/10654 1.0178416918039672e-61 5.036431482407779e-60 2.7301172863981654e-60 6158/23165/6138/4928/6144/2963/81929/6203/5434/5440/5903/6227/9349/4736/6206/6194/6234/6191/7175/6166/6128/51121/6132/9631/6147/6159/6129/6217/3843/5430/6222/5436/6176/6152/6136/6125/6224/6146/348995/51065/6154/6141/6202/79023/6123/57122/5441/6232/5438/6134/6169/5431/6160/6164/5435/6155/6175/5433/6218/5611/6209/6193/6173/23279/6210/6231/9688/6229/11224/6205/6165/79902/6130/2962/6142/6167/6204/6228/5437/23521/116832/23225/3320/140801/6156/6235/6143/6181/5439/6124/6207/8086/6139/6233/7311/6223/25873/3921/6188/6189/8021/6396/6135/6201/129401/6161/9045/6187/5432/55746/6168/6208/6157/6137/6170/200916/8480/6122/6133/6230 120 Reovirus R-HSA-72689 Formation of a pool of free 40S subunits 98/2430 101/10654 2.121839374170026e-59 1.0124205013896981e-57 5.488065749732998e-58 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/6234/27335/6191/6166/6128/51121/6132/6147/6159/8666/6129/6217/6222/6176/6152/6136/8668/8667/6125/6224/6146/51065/6154/8662/6141/10480/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/8663/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 98 Reovirus R-HSA-69618 Mitotic Spindle Checkpoint 105/2430 112/10654 4.396177977024679e-59 2.0252737163120592e-57 1.097847712592733e-57 220134/5905/55839/11130/4928/79682/81929/5903/10403/11065/54908/6249/55143/246184/55055/25936/5525/9735/80776/1783/1058/7321/991/401541/79019/5526/348235/80152/8697/9212/1063/8379/3619/79172/147841/348995/23421/55920/79023/57122/79980/64105/6232/332/1780/8881/23122/5528/5048/1781/5501/57405/8655/4085/23279/55166/51433/79902/3796/54821/5519/9183/81565/2491/1062/699/22919/1060/91687/119504/79003/5529/51143/51529/7324/83540/64682/29945/10393/11004/5527/51434/701/7514/9184/5518/25906/54820/5347/57551/84643/29882/6396/23332/25909/64946/9793/10726/81930/55746/140735/996/5515/1778/5516 105 Reovirus R-HSA-72766 Translation 193/2430 291/10654 4.72511404822482e-58 2.1042507894761197e-56 1.140659110589009e-56 6158/51264/8669/6138/6144/5464/6203/6182/51504/6227/9349/4736/6206/8891/6194/2107/122704/1965/29088/6234/27335/6191/6166/6128/10952/29093/51121/6132/1917/65993/1938/6147/6159/9521/8666/6129/1915/6217/1936/64979/9255/6222/1650/1983/6176/6152/6136/55176/92399/79590/8668/4528/8667/6125/1937/6727/10056/6224/6146/51065/6154/8662/6141/10480/6184/26986/6202/6123/6183/65003/28998/6232/58477/2935/6134/64983/6747/55052/6169/23480/6160/6731/6164/6155/6748/63931/8661/6175/51023/219927/6218/29927/6728/64963/9669/1933/64960/60559/6746/6209/1964/6193/6729/6173/6210/6231/6229/11224/6205/6165/6130/64968/6142/11222/6167/7458/6204/64969/51081/8663/6228/23521/116832/28972/51069/8894/65008/7965/1981/140801/85476/6156/6235/6143/1973/6181/55173/6124/6185/6207/51116/1977/6139/54948/6745/6726/6233/1975/23471/55168/9801/7311/6223/25873/8664/3646/63875/51386/6730/3921/6188/6189/9789/8665/6135/6201/23708/6161/65005/90701/9045/84340/6187/54998/64965/23478/6168/6208/51073/9553/6157/6137/6170/7284/8892/1974/200916/6122/6133/51021/29074/1968/6230 193 Reovirus R-HSA-5620912 Anchoring of the basal body to the plasma membrane 95/2430 98/10654 1.7915096004000406e-57 7.720828471401465e-56 4.185258421308074e-56 115106/22995/55559/79867/11258/22981/8636/7531/10142/54903/80776/11190/203068/54801/7532/55125/1454/10382/85302/51134/95681/121441/7277/79441/5116/54806/9814/91147/5048/1781/23354/80321/8766/22832/146057/8655/9738/79598/983/1639/55722/4957/10121/9702/5566/79959/132320/347240/84131/7846/7840/7283/3320/22919/27077/22994/11064/4867/79600/10540/84902/10733/1069/4751/117177/5577/80254/57545/26005/54930/5518/26123/10383/55835/54820/5347/23322/9662/80184/55142/23332/1453/22897/9793/4218/5108/261734/8481/57787/93323/10806/51259/55755/9657/1778 95 Reovirus R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 92/2430 94/10654 6.080414635459009e-57 2.5385731103041364e-55 1.3760938385512495e-55 114791/10844/115106/4926/22995/84617/55559/79861/440145/11258/22981/8636/7531/10142/11190/203068/54801/51807/7532/55125/1454/10382/347688/95681/121441/7277/79441/10381/5116/7278/112714/9814/653784/5048/1781/23354/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/113457/7283/347733/3320/22919/80097/10376/10426/22994/11064/10540/81027/10733/85378/1069/4751/5577/27175/80254/54930/5518/10383/55835/54820/5347/29922/84790/9662/80184/55142/23332/1453/22897/27229/9793/5108/8481/93323/7280/10806/55755/1778 92 Reovirus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 92/2430 95/10654 1.5037762452464899e-55 6.08801534439185e-54 3.300153291003461e-54 6158/6138/6144/6203/6227/9349/4736/6206/6194/2107/6234/6191/6166/6128/51121/6132/6147/6159/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/26986/6202/6123/6232/2935/6134/6169/6160/6164/4686/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/1981/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/23708/6161/9045/5976/6187/6168/22916/6208/6157/6137/6170/200916/6122/6133/6230 92 Reovirus R-HSA-5663205 Infectious disease 226/2430 383/10654 1.745748259865839e-54 6.85976375053165e-53 3.718497841447979e-53 6158/6884/5718/23165/3303/5689/5905/6138/8945/1173/4928/6144/2963/3837/3838/6917/81929/6203/5434/5440/5684/5903/6227/9349/8065/4736/6857/161/6206/6194/6234/6191/7175/6166/6128/5606/5682/51121/6132/9631/1499/1938/3159/6147/6159/6129/6217/5700/3843/5707/5430/6874/6222/5436/6176/6152/5690/6136/2060/7520/8106/6125/5717/4869/821/6500/84168/6749/811/6224/6146/348995/51065/6154/6141/9636/10015/143471/6202/79023/5706/6123/57122/5705/5441/10197/6232/5438/6134/6169/5431/6160/6164/5435/79720/4686/7316/6155/10213/5709/9978/6175/293/5433/6218/5611/920/292/4836/6209/6193/6714/6173/23279/6210/6231/9688/6229/11224/8148/6205/6165/9861/79902/6130/5715/9525/2962/6142/10898/6167/3840/6204/23327/11168/5701/867/5688/6228/5437/23521/5687/116832/23225/999/5685/5683/5708/9146/3320/5692/5686/140801/6156/6235/6143/5710/2068/6181/5439/6124/5702/5901/6207/8086/5478/3836/6139/30011/5704/6233/2885/3326/6844/7514/163/1025/7311/6223/25873/6881/1213/5610/6880/3921/6188/6189/8021/7040/7251/11198/6396/6135/6201/129401/375/6161/5694/3304/6829/1104/51497/2547/801/9045/6187/1022/5432/55746/6168/22916/5693/6208/6157/6137/6170/200916/8480/6122/6133/291/7296/7314/5879/25920/6230 226 Reovirus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 134/2430 171/10654 2.8359156786705386e-54 1.0662992837158726e-52 5.780128484057046e-53 10921/6158/5718/5689/6138/6144/6203/5684/6227/9349/4736/6206/6194/2107/6234/6191/6166/6128/5682/51121/6132/6147/6159/6129/6217/5700/5707/6222/6176/6152/5690/6136/6125/5717/6224/6146/51065/6154/6141/26986/143471/6202/5706/6123/5705/10197/6232/26019/2935/6134/6169/6160/55110/22794/6164/4686/7316/6155/10213/5709/9978/6175/6218/4116/65109/6209/6193/6173/6210/6231/6229/11224/6205/6165/9861/6130/5715/6142/6167/6204/5701/5688/6228/23521/5687/116832/5685/1605/5683/5708/5692/5686/1981/140801/6156/6235/6143/5710/6181/6124/5702/8453/6207/9939/6139/5704/6233/7311/6223/25873/3921/6188/6189/9775/6135/6201/23708/6161/5694/9045/6187/65110/6168/22916/5693/6208/6157/6137/6170/200916/6122/6133/7314/6230 134 Reovirus R-HSA-156842 Eukaryotic Translation Elongation 90/2430 93/10654 2.873261542946962e-54 1.0662992837158726e-52 5.780128484057046e-53 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/1917/1938/6147/6159/6129/1915/6217/1936/6222/6176/6152/6136/6125/1937/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/1933/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 90 Reovirus R-HSA-69620 Cell Cycle Checkpoints 188/2430 293/10654 3.5096173177369656e-53 1.2672564152693475e-51 6.869464337419722e-52 5718/1017/220134/6118/5689/5905/55839/11130/4928/79682/81929/9134/5684/5903/10403/5000/11065/54908/6249/55143/5682/246184/55055/5883/25936/5525/9735/7531/51512/1029/80776/1783/1058/5700/7486/7321/5707/991/401541/79019/5526/10111/7532/8317/10971/348235/80152/8697/5690/9212/1063/8379/5717/3619/79172/898/2810/147841/348995/23421/4173/11200/143471/545/55920/79023/5706/9133/472/57122/5705/79980/64105/10197/7336/6232/7534/332/580/1780/8881/11073/23122/5528/5048/1781/7316/10213/5709/4174/891/5501/57405/8655/4085/983/1026/84515/641/4171/23279/55166/51433/9861/79902/3796/5715/54821/9656/5519/6119/9183/81565/7341/5701/2491/5688/1062/699/5687/5685/5683/5708/22919/5692/5985/5686/1060/91687/119504/165918/79003/5529/5710/51143/1111/5702/7157/8900/51529/5984/7324/83540/64682/29945/10393/8924/11004/5704/6233/5527/51434/701/672/7514/7311/9184/79184/5518/25906/54820/5347/57551/7156/84643/6117/29882/6396/7334/5694/23332/25909/7465/64946/9793/10726/81930/55746/5693/140735/4176/7529/7314/996/4193/5515/1778/5516 188 Reovirus R-HSA-5663220 RHO GTPases Activate Formins 117/2430 140/10654 4.0337475757832123e-53 1.418180726643782e-51 7.687585407586841e-52 220134/5905/55839/11130/84617/4928/79682/81929/5903/10403/79861/54908/71/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/401541/79019/5526/51807/348235/80152/10382/9212/389/1063/347688/8379/3619/79172/147841/7277/348995/23421/55920/79023/10381/57122/79980/64105/7278/6232/332/112714/1780/23122/5528/3688/5048/1781/5501/57405/8655/4085/5216/6714/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/7846/113457/347733/22919/1060/91687/79003/10376/23002/5529/51143/998/81027/83540/11004/5527/701/7514/23380/9184/5518/10383/54820/5347/387/57551/60/84790/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/7280/5879/5515/1778/5516 117 Reovirus R-HSA-156902 Peptide chain elongation 86/2430 89/10654 1.0403111804244058e-51 3.563732659094888e-50 1.9318059166855362e-50 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/1938/6147/6159/6129/1915/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 86 Reovirus R-HSA-391251 Protein folding 93/2430 101/10654 1.4125132905512918e-50 4.652769131483273e-49 2.522143998156706e-49 2788/10694/402/26224/84617/6000/9134/8841/54331/79861/22803/2629/59345/1459/5204/8787/51807/8237/10575/10382/10528/6903/10681/5203/898/51764/1460/7277/94235/10381/7278/112714/63971/7203/10517/10576/908/55970/8786/6774/1457/2792/6902/6905/26272/10471/26985/11328/26330/1155/2793/26270/6950/7846/113457/347733/2785/10376/55294/2783/26190/2784/10238/7411/55135/2782/5082/7157/81027/2786/2771/10574/6468/10564/83752/10383/60/54461/84790/22948/6499/26234/10693/8877/2791/7280/84261/9628/6904/5201/2790/2787/5202 93 Reovirus R-HSA-72764 Eukaryotic Translation Termination 88/2430 93/10654 1.4278707663983097e-50 4.652769131483273e-49 2.522143998156706e-49 6158/6138/6144/6203/51504/6227/9349/4736/6206/6194/2107/6234/6191/6166/6128/51121/6132/6147/6159/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/2935/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/23708/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 88 Reovirus R-HSA-192823 Viral mRNA Translation 85/2430 89/10654 7.868424214758283e-50 2.502908274027873e-48 1.3567608671061903e-48 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6147/6159/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/5611/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 85 Reovirus R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 80/2430 82/10654 3.2479301421807242e-49 9.861896977166926e-48 5.345875449330953e-48 114791/10844/115106/22995/55559/440145/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/653784/5048/1781/23354/728642/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/984/80097/10426/22994/11064/10540/10733/85378/1069/4751/5577/27175/80254/54930/5518/10383/55835/54820/5347/29922/9662/80184/55142/23332/1453/22897/27229/9793/5108/8481/93323/10806/55755/1778 80 Reovirus R-HSA-380287 Centrosome maturation 80/2430 82/10654 3.2479301421807242e-49 9.861896977166926e-48 5.345875449330953e-48 114791/10844/115106/22995/55559/440145/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/653784/5048/1781/23354/728642/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/984/80097/10426/22994/11064/10540/10733/85378/1069/4751/5577/27175/80254/54930/5518/10383/55835/54820/5347/29922/9662/80184/55142/23332/1453/22897/27229/9793/5108/8481/93323/10806/55755/1778 80 Reovirus R-HSA-141424 Amplification of signal from the kinetochores 89/2430 96/10654 4.4265492372986805e-49 1.28562386544153e-47 6.969029462840942e-48 220134/5905/55839/11130/4928/79682/81929/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/401541/79019/5526/348235/80152/9212/1063/8379/3619/79172/147841/348995/23421/55920/79023/57122/79980/64105/6232/332/1780/23122/5528/5048/1781/5501/57405/8655/4085/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/22919/1060/91687/79003/5529/51143/83540/11004/5527/701/7514/9184/5518/54820/5347/57551/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/5515/1778/5516 89 Reovirus R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 89/2430 96/10654 4.4265492372986805e-49 1.28562386544153e-47 6.969029462840942e-48 220134/5905/55839/11130/4928/79682/81929/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/401541/79019/5526/348235/80152/9212/1063/8379/3619/79172/147841/348995/23421/55920/79023/57122/79980/64105/6232/332/1780/23122/5528/5048/1781/5501/57405/8655/4085/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/22919/1060/91687/79003/5529/51143/83540/11004/5527/701/7514/9184/5518/54820/5347/57551/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/5515/1778/5516 89 Reovirus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 83/2430 88/10654 1.9989616810559388e-47 5.682154906150499e-46 3.0801470023885462e-46 8454/115106/8945/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/84962/55125/1454/10382/95681/6500/121441/7277/79441/9133/5116/9814/5048/1781/23354/7316/80321/891/8655/9738/983/1639/6790/55722/4957/10121/9702/5566/79959/84131/23291/7846/7840/7283/3320/22919/22994/11064/10540/10733/79866/1069/4751/5577/6233/80254/7311/54930/5518/10133/10383/55835/54820/5347/9662/80184/55142/23332/1453/22897/9793/4218/5108/8481/93323/10806/55755/7314/1778 83 Reovirus R-HSA-2408557 Selenocysteine synthesis 86/2430 93/10654 3.2237356468161656e-47 8.972730883638327e-46 4.863881853091056e-46 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6147/6159/6129/6217/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/60678/6169/6160/6164/6155/6175/6218/79048/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/6230 86 Reovirus R-HSA-390466 Chaperonin-mediated protein folding 87/2430 95/10654 7.165095189029807e-47 1.953585137253841e-45 1.0589872159081649e-45 2788/10694/26224/84617/6000/9134/8841/54331/79861/22803/2629/59345/1459/5204/8787/51807/8237/10575/10382/10528/10681/5203/898/51764/1460/7277/94235/10381/7278/112714/63971/7203/10517/10576/908/55970/8786/6774/1457/2792/26272/10471/26985/11328/26330/2793/26270/6950/7846/113457/347733/2785/10376/55294/2783/26190/2784/10238/7411/55135/2782/5082/7157/81027/2786/2771/10574/6468/10564/83752/10383/60/54461/84790/22948/6499/26234/10693/8877/2791/7280/84261/9628/5201/2790/2787/5202 87 Reovirus R-HSA-376176 Signaling by ROBO receptors 147/2430 218/10654 1.288405240584299e-45 3.4426188028412466e-44 1.866153274783153e-44 10921/6158/5718/5689/6138/6144/6203/5684/6227/9349/4736/6206/6194/2107/6234/6191/6166/6128/5682/51121/6132/2817/6147/6159/6129/4690/6217/5700/5707/6222/6176/6152/5690/6136/6125/5717/6224/6146/51065/6154/6141/26986/143471/6202/5706/6123/5705/10197/6232/26019/2935/6134/6169/6160/55110/22794/23122/6164/4686/7316/6155/10213/5709/9978/6175/6218/4116/5216/65109/6209/6193/6714/6173/6210/6231/6229/11224/6205/6165/9861/5566/6130/5715/6142/6167/6204/5701/5688/6228/23521/5687/116832/5685/1605/5683/5708/5692/5686/1981/7408/140801/6156/6235/6143/5710/6181/6124/5702/998/8453/6207/9939/6139/10487/5704/6233/23380/7311/6223/25873/387/3921/6188/6189/9775/6135/6201/23708/6161/5694/23332/9045/6187/65110/6168/22916/5693/6208/6157/6137/6170/200916/6122/6133/7314/5879/6230 147 Reovirus R-HSA-8854518 AURKA Activation by TPX2 71/2430 73/10654 1.912960211887779e-43 5.0112055746707306e-42 2.7164429840635536e-42 115106/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/22974/10382/3161/95681/121441/7277/79441/5116/9814/5048/1781/23354/80321/8655/9738/983/1639/6790/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/22994/11064/10540/10733/1069/4751/5577/80254/54930/5518/10383/55835/54820/5347/9662/80184/55142/23332/1453/22897/9793/5108/8481/93323/10806/55755/1778 71 Reovirus R-HSA-380259 Loss of Nlp from mitotic centrosomes 68/2430 70/10654 1.5837668338996081e-41 3.99228771715071e-40 2.164114362905522e-40 115106/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/5048/1781/23354/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/22994/11064/10540/10733/1069/4751/5577/80254/54930/5518/10383/55835/54820/5347/9662/80184/55142/23332/1453/22897/9793/5108/8481/93323/10806/55755/1778 68 Reovirus R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 68/2430 70/10654 1.5837668338996081e-41 3.99228771715071e-40 2.164114362905522e-40 115106/22995/55559/11258/22981/8636/7531/10142/11190/203068/54801/7532/55125/1454/10382/95681/121441/7277/79441/5116/9814/5048/1781/23354/80321/8655/9738/983/1639/55722/4957/10121/9702/5566/79959/84131/7846/7840/7283/3320/22919/22994/11064/10540/10733/1069/4751/5577/80254/54930/5518/10383/55835/54820/5347/9662/80184/55142/23332/1453/22897/9793/5108/8481/93323/10806/55755/1778 68 Reovirus R-HSA-5617833 Cilium Assembly 133/2430 201/10654 6.122639635360091e-40 1.5147863986742743e-38 8.211259394011193e-39 115106/10694/582/22995/84617/79738/55559/79867/79861/11258/22981/8636/7531/10142/54903/80776/11190/203068/3842/54801/51807/7532/10575/55125/1454/10382/123016/85302/347688/51134/95681/121441/7277/79441/10013/26146/10381/5116/585/7278/112714/54806/9814/7203/91147/5048/1781/23354/10576/80321/8766/22832/146057/8655/9738/79598/983/1639/89891/55722/4957/10121/9702/5566/79959/132320/347240/84131/6950/55212/7846/7840/113457/7283/347733/3320/8729/22919/10376/27077/22994/11064/4867/79600/10540/84902/81027/10733/1069/4751/117177/5577/80254/57545/26005/54930/5518/26123/10383/55835/54820/583/5347/23322/84790/22948/378/9662/80184/55142/23332/92482/1453/8195/22897/9793/129880/22920/4218/5108/261734/8481/166379/27241/57787/140735/93323/7280/10806/51259/55755/9657/1778 133 Reovirus R-HSA-2408522 Selenoamino acid metabolism 91/2430 118/10654 4.113189925798316e-36 9.991312256121e-35 5.416028074544002e-35 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6147/6159/9521/6129/6217/191/9255/6222/6176/6152/6136/6125/6224/6146/51065/6154/6141/6202/6123/6232/6134/60678/6169/6160/6164/6155/6175/6218/79048/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/7965/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/7296/6230 91 Reovirus R-HSA-2262752 Cellular responses to stress 229/2430 479/10654 7.309956857312132e-35 1.7439468502444657e-033 9.453478041035237e-34 1912/5718/1017/23165/3303/7014/6118/5689/3725/84617/4928/25913/81929/9134/1019/5684/5903/79861/11065/7175/11258/5606/5682/9631/3159/246184/112399/7531/1029/7027/1915/1783/526/5700/7321/5707/2146/10111/8535/51807/84962/6045/8697/5690/10382/9114/57690/5594/3308/347688/23677/5717/27327/80012/898/10049/5931/10294/5925/55860/3091/830/7013/7277/348995/10013/143471/545/79023/5706/472/10381/57122/5705/10197/3337/192670/7278/3313/10808/112714/1780/8881/7323/1781/7316/10213/5709/9978/10935/3305/8655/527/6774/1026/1639/9261/1911/9532/54205/832/26277/6667/2289/9588/23279/9688/10121/7415/6647/51433/9861/79902/64223/7322/91582/5715/6119/5598/5928/1432/2932/5701/5688/1387/84733/5687/57805/7846/23225/113457/529/2908/5685/5683/3309/347733/5708/3320/5692/5686/2033/23512/119504/7266/57332/10376/6195/5710/51143/3301/25994/7428/5702/192669/10540/9531/7157/81027/8453/8900/51529/8086/23135/7324/10963/4001/64682/29945/10393/23112/5704/6233/51434/3326/2475/55004/3306/51343/6196/7311/367/538/25906/10383/23411/84790/8021/9529/4343/8726/55662/6117/6197/29882/5599/6396/648/129401/5600/5694/3304/3312/523/201163/23466/26523/5052/3297/57521/55746/5693/55466/140735/7280/2288/5034/8480/10919/10728/829/7296/7314/996/6015/51182/4193/2950/1778 229 Reovirus R-HSA-72649 Translation initiation complex formation 56/2430 58/10654 6.936691815261292e-34 1.5978310802050148e-32 8.661422811070361e-33 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/8668/8667/6224/51065/8662/10480/26986/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1974/1968/6230 56 Reovirus R-HSA-72702 Ribosomal scanning and start codon recognition 56/2430 58/10654 6.936691815261292e-34 1.5978310802050148e-32 8.661422811070361e-33 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/1983/8668/8667/6224/51065/8662/10480/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1974/1968/6230 56 Reovirus R-HSA-8953897 Cellular responses to external stimuli 231/2430 493/10654 1.8041916817176403e-33 4.085423875889436e-32 2.2146010294767822e-32 1912/5718/1017/23165/3303/7014/6118/5689/3725/84617/4928/25913/81929/9134/1019/5684/5903/79861/11065/7175/11258/5606/5682/9631/3159/246184/112399/7531/1029/7027/1915/1783/526/5700/7321/5707/2146/10111/8535/51807/84962/6045/8697/5690/10382/9114/57690/5594/3308/347688/23677/5717/27327/80012/898/10049/5931/10294/5925/55860/3091/830/7013/7277/348995/10013/143471/545/79023/5706/472/10381/57122/5705/10197/3337/192670/7278/3313/10808/112714/1780/8881/7323/1781/7316/10213/5709/9978/1465/10935/3305/8655/527/6774/1026/1639/9261/1911/9532/54205/832/26277/6667/2289/9588/23279/9688/10121/7415/6647/51433/9861/79902/64223/7322/91582/5715/6119/5598/5928/1432/2932/5701/5688/1387/84733/5687/57805/7846/23225/113457/529/2908/5685/5683/3309/347733/5708/3320/5692/5686/2033/23512/119504/7266/57332/10376/6195/5710/51143/3301/25994/7428/5702/192669/10540/9531/7157/81027/8453/8900/51529/8086/23135/7324/10963/4001/64682/29945/10393/23112/5704/6233/51434/3326/2475/55004/3306/51343/6196/7311/367/538/25906/10383/23411/84790/8021/9529/4343/8726/55662/6117/4520/6197/29882/5599/6396/648/129401/5600/5694/3304/3312/523/201163/23466/26523/5052/3297/57521/55746/5693/55466/140735/7280/2288/5034/8480/10919/10728/829/7296/7314/996/6015/51182/4193/2950/1778 231 Reovirus R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 56/2430 59/10654 1.0639837352760137e-32 2.3691371172145902e-31 1.284247034859469e-31 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/8668/8667/6224/51065/8662/10480/26986/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1974/1968/6230 56 Reovirus R-HSA-72165 mRNA Splicing - Minor Pathway 51/2430 52/10654 4.936620005809615e-32 1.0812007094691222e-30 5.860905201030224e-31 23451/2963/6635/5434/5440/6633/55599/6432/6431/6632/24148/154007/83443/5430/85437/4904/5436/10081/51639/11325/6637/23450/5441/5438/79622/5431/5435/10594/4686/5433/9343/55954/9416/57819/8233/2962/5437/23020/5439/11066/9410/6636/6634/6427/6426/10907/5432/22916/10992/10262/6628 51 Reovirus R-HSA-73856 RNA Polymerase II Transcription Termination 60/2430 67/10654 2.646934292127548e-31 5.703716474649039e-30 3.091834962620973e-30 10921/7919/53981/6635/6432/8683/6431/6430/7884/134353/84271/11051/79869/51585/6428/8106/10212/29894/84967/6637/199746/55110/22794/81608/4686/9785/8189/11338/4116/1477/10978/65109/84321/7307/6429/1478/10898/9984/10250/10569/26097/10189/51362/9295/51692/23283/9939/9877/6636/6634/10914/9775/57187/84248/6427/6426/22916/1479/55339/6628 60 Reovirus R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 49/2430 51/10654 1.873610586192238e-29 3.973244036750524e-28 2.153791283709707e-28 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6222/8668/8667/6224/51065/8662/10480/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/6204/8663/6228/8894/6235/6207/6233/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1968/6230 49 Reovirus R-HSA-1852241 Organelle biogenesis and maintenance 155/2430 296/10654 3.1522727079926734e-29 6.580369277934706e-28 3.5670454327285513e-28 115106/10694/582/22995/84617/79738/55559/79867/8841/79861/11258/22981/8636/7531/10142/54903/80776/11190/203068/3842/54801/51807/7532/10575/55125/1454/10382/123016/85302/347688/51134/95681/121441/7277/79441/10013/26146/10381/5116/585/7278/3313/112714/54806/9814/7203/91147/5048/1781/23354/10576/80321/2553/8766/9611/5469/22832/10989/23409/146057/8655/9738/79598/54927/983/1639/54205/89891/55722/4957/10121/9702/5566/79959/132320/347240/84131/1432/1387/6950/55212/7846/7840/113457/7283/347733/3320/8729/22919/10376/27077/22994/11064/4867/79600/10540/84902/81027/10733/1069/4751/117177/10498/5577/80254/57545/55902/26005/54930/11232/23054/5518/26123/10383/1386/55835/54820/583/5347/23322/84790/22948/6742/378/5600/9662/80184/55142/23332/92482/1453/8195/22897/801/9793/129880/22920/4218/5108/133522/261734/7019/8481/166379/2746/27241/57787/140735/93323/7280/10806/51259/55755/9657/1778 155 Reovirus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 67/2430 86/10654 2.350283372991866e-27 4.7575433126017165e-26 2.5789393311298303e-26 8454/5718/1017/5689/8945/5684/11065/5682/246184/5700/7321/5707/991/8697/5690/9212/5717/6500/143471/5706/5705/10197/8881/7316/10213/5709/891/4085/983/6790/51433/9861/5715/5701/5688/5687/6502/5685/5683/5708/5692/5686/119504/5710/5702/8900/51529/8556/7324/64682/29945/10393/4751/5704/6233/51434/701/51343/7311/9184/25906/5347/29882/5694/5693/7314/996 67 Reovirus R-HSA-453276 Regulation of mitotic cell cycle 67/2430 86/10654 2.350283372991866e-27 4.7575433126017165e-26 2.5789393311298303e-26 8454/5718/1017/5689/8945/5684/11065/5682/246184/5700/7321/5707/991/8697/5690/9212/5717/6500/143471/5706/5705/10197/8881/7316/10213/5709/891/4085/983/6790/51433/9861/5715/5701/5688/5687/6502/5685/5683/5708/5692/5686/119504/5710/5702/8900/51529/8556/7324/64682/29945/10393/4751/5704/6233/51434/701/51343/7311/9184/25906/5347/29882/5694/5693/7314/996 67 Reovirus R-HSA-72187 mRNA 3'-end processing 52/2430 58/10654 2.488208116611479e-27 4.9615612593924417e-26 2.689532104051371e-26 10921/7919/53981/6432/8683/6431/6430/84271/11051/79869/51585/6428/8106/10212/29894/199746/55110/22794/81608/4686/9785/8189/11338/4116/1477/10978/65109/84321/7307/6429/1478/10898/9984/10250/10569/26097/10189/51362/9295/51692/23283/9939/9877/10914/9775/57187/84248/6427/6426/22916/1479/55339 52 Reovirus R-HSA-195258 RHO GTPase Effectors 162/2430 327/10654 5.916154210142877e-27 1.162350297757483e-25 6.300795815136686e-26 220134/5905/55839/11130/84617/4928/79682/81929/5590/5903/1072/10403/79861/54908/71/6249/55143/1499/55055/25936/5525/9735/7531/80776/4690/1783/1058/10093/991/10006/401541/79019/5526/51807/2316/7532/10971/348235/80152/4771/10382/9212/389/5594/1063/347688/8379/3798/3619/10627/79172/1080/2810/147841/7277/348995/23421/55920/79023/10381/57122/79980/64105/6280/7278/6232/7534/332/112714/1780/6242/23122/5528/3688/5048/1781/5501/57405/8655/4085/5585/5216/10552/10094/6279/6714/23279/55166/79902/3796/54821/5519/9183/1432/81565/2491/1062/699/7846/999/113457/89953/347733/22919/1060/91687/79003/10376/391/23002/5529/11113/51143/998/81027/23028/83540/11004/5527/2885/10096/5580/701/10097/9055/7514/23380/9184/9928/367/8826/29941/5518/3799/10383/54820/5347/387/57551/60/5300/84790/84643/6396/5600/23332/25909/801/64946/9793/10726/10109/5586/81930/55746/140735/7280/7529/5879/5515/1778/5516 162 Reovirus R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 49/2430 55/10654 1.5767801575777785e-25 3.0530120152520468e-24 1.654957663483618e-24 3303/84617/79861/11258/1783/51807/10382/347688/10294/55860/830/7277/10381/3337/7278/112714/1780/1781/3305/8655/1639/832/2289/10121/7846/113457/2908/347733/3320/10376/51143/3301/10540/81027/10963/3326/3306/367/10383/84790/3304/3312/55466/140735/7280/2288/10728/829/1778 49 Reovirus R-HSA-1268020 Mitochondrial protein import 54/2430 64/10654 1.7326743829554942e-25 3.306932822326486e-24 1.7926014668772628e-24 2395/90639/10063/26519/197257/131118/10245/56942/10452/134266/26520/3313/7416/100188893/5009/51025/400916/4714/293/10440/50/54927/10165/1678/3329/84269/150274/56993/100287932/26521/51142/100272147/10469/8604/29090/26517/1431/6901/79145/92609/80273/9804/617/54543/3421/1537/29928/388753/2671/401505/131474/26515/51287/291 54 Reovirus R-HSA-72202 Transport of Mature Transcript to Cytoplasm 64/2430 84/10654 3.230556744056588e-25 6.0789067747318324e-24 3.295215774515837e-24 10921/23165/7919/53981/4928/81929/5903/6432/8683/6431/6430/7175/9631/7884/84271/6428/10212/29894/199746/348995/79023/57122/55110/22794/81608/4686/9785/8189/11338/4116/65109/84321/7307/6429/23279/9688/79902/10898/9984/10250/10569/23225/26097/10189/51362/9295/10482/51692/8086/9939/1977/9877/8021/9775/57187/84248/6396/129401/6427/6426/55746/22916/8480/55339 64 Reovirus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 62/2430 80/10654 3.5146176466317925e-25 6.5215682998612156e-24 3.535170966202738e-24 8454/5718/1017/5689/8945/5684/11065/5682/246184/5700/7321/5707/991/8697/5690/5717/6500/143471/5706/5705/10197/8881/7316/10213/5709/891/4085/983/51433/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/119504/5710/5702/8900/51529/7324/64682/29945/10393/5704/6233/51434/701/51343/7311/9184/25906/5347/29882/5694/5693/7314/996 62 Reovirus R-HSA-6807070 PTEN Regulation 89/2430 140/10654 3.597297363903576e-25 6.5835469564043524e-24 3.568767968804124e-24 1912/5718/5689/27161/3725/5684/8841/5682/5468/1459/5700/5707/2146/5978/8535/10273/207/6045/5690/57690/5594/5717/27327/80012/5931/1460/143471/5706/5705/10197/192670/7316/10213/5709/1457/1911/4734/1108/2122/11060/9861/64223/81847/10014/5715/5928/5701/5688/84733/5687/5685/5683/5708/5692/5686/23512/57332/5728/2444/5710/6615/5702/192669/3066/3065/7157/1107/23028/8975/5371/23112/5704/6233/2475/55004/7311/1386/4343/8726/648/5694/23466/26523/7874/57521/5693/23608/7314/6015 89 Reovirus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 60/2430 77/10654 1.2433587580358152e-24 2.2447666226160123e-23 1.2168290548060324e-23 5718/5689/84617/5684/79861/5682/51512/5700/5707/51807/5690/10382/347688/5717/7277/143471/5706/9133/10381/5705/10197/7278/112714/7316/10213/5709/891/983/1026/9861/5715/5701/5688/5687/7846/113457/5685/5683/347733/5708/3320/22919/5692/5686/10376/5710/5702/7157/81027/5704/6233/3326/7311/10383/5347/84790/5694/5693/7280/7314 60 Reovirus R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 38/2430 39/10654 9.848436497249756e-24 1.7543348213767565e-22 9.5097885054145e-23 10694/26224/9134/8841/22803/2629/8237/10575/10528/898/63971/7203/10517/10576/908/6774/26272/26985/11328/26330/26270/6950/55294/26190/10238/55135/7157/10574/6468/10564/83752/54461/22948/6499/26234/10693/8877/84261 38 Reovirus R-HSA-69242 S Phase 95/2430 161/10654 2.684779362804752e-23 4.719559511456774e-22 2.558349309708683e-22 8454/5718/1017/6118/5689/9134/1019/5684/5000/11065/5682/246184/7027/5700/7321/5707/207/8697/5690/5717/6500/898/10274/5925/23244/4173/143471/5706/5705/10735/10197/4149/23047/8881/5885/7316/10213/5709/9978/4174/5753/1026/84515/5111/5426/4171/4609/51433/9861/5715/6119/5928/2932/5701/5688/5687/6502/5685/5683/5708/5692/5985/5686/119504/8243/9126/595/5710/5702/8900/51529/5984/7324/64682/29945/10393/5704/6233/51434/51343/7311/25906/113130/6117/29882/5981/5694/7465/5424/1022/5693/4176/7314/996/56655 95 Reovirus R-HSA-6790901 rRNA modification in the nucleus and cytosol 51/2430 62/10654 4.020356951956348e-23 6.975580373784001e-22 3.7812789924073374e-22 9136/2091/6203/51504/55127/55813/8602/6194/25879/55226/10436/27292/9277/84128/56902/10528/84135/27340/55623/57050/4839/88745/51602/51096/134430/55272/92856/65083/9724/1736/11056/54555/9790/51077/10171/5822/10199/25926/23160/27341/10607/11103/6201/51202/57647/6187/6208/10885/22984/10813/79050 51 Reovirus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 58/2430 76/10654 4.943002629449261e-23 8.466476298646426e-22 4.589454533145872e-22 5718/5689/5684/11065/5682/246184/5700/7321/5707/991/8697/5690/5717/143471/5706/5705/10197/8881/7316/10213/5709/891/4085/983/51433/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/119504/5710/5702/8900/51529/7324/64682/29945/10393/4751/5704/6233/51434/701/7311/9184/25906/5347/29882/5694/5693/7314/996 58 Reovirus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 57/2430 75/10654 1.6845452311613401e-22 2.8488005428247475e-21 1.5442599853950724e-21 5718/5689/5684/11065/5682/246184/5700/7321/5707/991/8697/5690/5717/143471/5706/5705/10197/8881/7316/10213/5709/891/4085/983/51433/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/119504/5710/5702/8900/51529/7324/64682/29945/10393/4751/5704/6233/51434/701/7311/9184/25906/29882/5694/5693/7314/996 57 Reovirus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 56/2430 73/10654 1.7825516799649127e-22 2.976861305541404e-21 1.6136783629156052e-21 5718/5689/5684/11065/5682/246184/5700/7321/5707/991/8697/5690/5717/143471/5706/5705/10197/8881/7316/10213/5709/4085/983/51433/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/119504/5710/5702/8900/51529/7324/64682/29945/10393/4751/5704/6233/51434/701/7311/9184/25906/29882/5694/5693/7314/996 56 Reovirus R-HSA-69052 Switching of origins to a post-replicative state 64/2430 90/10654 1.9663073696820164e-22 3.2431933899940416e-21 1.7580499939457144e-21 8454/5718/1017/5689/9134/5684/5000/11065/5682/246184/5700/7321/5707/8697/5690/5717/6500/898/4173/143471/5706/5705/10197/8881/7316/10213/5709/9978/4174/84515/4171/51433/9861/5715/5701/5688/5687/6502/5685/5683/5708/5692/5686/119504/5710/5702/8900/51529/7324/64682/29945/10393/5704/6233/51434/51343/7311/25906/29882/5694/5693/4176/7314/996 64 Reovirus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 55/2430 72/10654 6.10308199495697e-22 9.823756078629533e-21 5.325200269537597e-21 5718/5689/5684/11065/5682/246184/5700/7321/5707/991/8697/5690/9212/5717/143471/5706/5705/10197/8881/7316/10213/5709/6790/51433/9861/5715/5701/5688/5687/6502/5685/5683/5708/5692/5686/119504/5710/5702/51529/7324/64682/29945/10393/5704/6233/51434/51343/7311/25906/5347/29882/5694/5693/7314/996 55 Reovirus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 55/2430 72/10654 6.10308199495697e-22 9.823756078629533e-21 5.325200269537597e-21 5718/5689/5684/11065/5682/246184/5700/7321/5707/991/8697/5690/5717/143471/5706/5705/10197/8881/7316/10213/5709/4085/983/51433/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/119504/5710/5702/8900/51529/7324/64682/29945/10393/5704/6233/51434/701/7311/9184/25906/29882/5694/5693/7314/996 55 Reovirus R-HSA-9609507 Protein localization 93/2430 163/10654 2.162856901244836e-21 3.439972404837025e-20 1.8647187319003096e-20 1891/2395/54677/351/90639/3295/54332/9218/10952/10063/26519/197257/7321/51/131118/8310/5621/10245/56942/10452/134266/26520/8266/5824/3313/10005/23480/7416/100188893/7323/5009/51025/8239/7316/400916/4714/293/10440/50/7917/54927/10165/1678/3329/84269/7322/150274/56993/1962/100287932/26521/51142/100272147/118424/10469/8604/4843/10455/29090/26517/1431/6901/54363/79145/2010/92609/8540/6233/6844/80273/9804/617/7311/54543/83752/373156/3421/3155/224/1537/5195/29928/388753/2671/401505/6449/5191/131474/26515/51287/291/7314/30 93 Reovirus R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 32/2430 32/10654 2.4558486538700074e-21 3.8600162371415646e-20 2.0924134660836717e-20 10694/84617/79861/5204/51807/10575/10382/5203/7277/10381/7278/112714/7203/10576/908/10471/6950/7846/113457/347733/10376/7411/81027/10574/10383/60/84790/22948/10693/7280/5201/5202 32 Reovirus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 54/2430 72/10654 6.489918769614841e-21 1.0082013344424914e-19 5.465194753359865e-20 5718/1017/5689/9134/5684/11065/5682/246184/5700/7321/5707/8697/5690/5717/898/143471/5706/5705/10197/8881/7316/10213/5709/51433/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/119504/5710/5702/8900/51529/7324/64682/29945/10393/5704/6233/51434/51343/7311/25906/29882/5694/5693/7314/996 54 Reovirus R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 55/2430 75/10654 1.7151623426539522e-20 2.633858494006529e-19 1.4277455435522312e-19 10921/23165/7919/4928/81929/5903/6432/8683/6431/6430/7175/9631/84271/6428/10212/199746/348995/79023/57122/55110/22794/4686/9785/11338/4116/65109/84321/7307/6429/23279/9688/79902/9984/10250/10569/23225/26097/10189/51362/9295/10482/8086/9939/9877/8021/9775/57187/84248/6396/129401/6427/6426/55746/22916/8480 55 Reovirus R-HSA-69239 Synthesis of DNA 74/2430 119/10654 2.614585079345766e-20 3.969415529552208e-19 2.1517159504663717e-19 8454/5718/1017/6118/5689/9134/5684/5000/11065/5682/246184/5700/7321/5707/8697/5690/5717/6500/898/4173/143471/5706/5705/10197/8881/7316/10213/5709/9978/4174/84515/5111/5426/4171/51433/9861/5715/6119/5701/5688/5687/6502/5685/5683/5708/5692/5985/5686/119504/5710/5702/8900/51529/5984/7324/64682/29945/10393/5704/6233/51434/51343/7311/25906/6117/29882/5981/5694/5424/5693/4176/7314/996/56655 74 Reovirus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 49/2430 63/10654 2.78702555251325e-20 4.183669818154721e-19 2.2678575755518815e-19 5718/5689/5684/11065/5682/246184/5700/7321/5707/8697/5690/5717/5706/5705/10197/8881/7316/10213/5709/51433/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/119504/5710/5702/51529/7324/64682/29945/10393/5704/6233/51434/51343/7311/25906/29882/5694/5693/7314/996 49 Reovirus R-HSA-3700989 Transcriptional Regulation by TP53 161/2430 365/10654 3.859210032410189e-20 5.72878289255557e-19 3.105422809705509e-19 9377/6884/1017/6118/27161/3725/2963/6917/9134/5434/5440/8621/1329/5883/7531/1029/7027/1459/79370/7486/5430/10111/8793/6874/8445/7532/207/10971/5436/1345/9997/22974/9212/57690/4849/4869/27327/898/5931/4850/2810/1460/6749/11200/545/472/5441/192670/7534/332/5438/580/5431/11073/9337/5435/7316/5433/891/1351/80196/2539/84289/1457/54971/983/1026/54205/6790/641/5111/25904/1108/1643/8148/246175/64223/2962/9656/5519/6119/5928/1432/1387/4848/5437/1350/23019/2821/6794/5985/2033/10128/5728/2068/5439/1111/192669/3066/3065/7157/1107/8900/5984/91875/8626/5371/23112/10498/6233/5527/2475/55004/672/55571/1025/7311/6881/5562/5518/1386/55835/6880/10419/5300/7156/581/4343/6117/11198/1327/5600/57472/4697/9167/3276/85456/6829/29883/26523/51497/7874/5052/1020/2744/10397/1022/5432/57521/7248/26155/26013/10919/7529/7296/7314/253260/4193/5515/25920/5516 161 Reovirus R-HSA-1257604 PIP3 activates AKT signaling 126/2430 264/10654 2.001374508651213e-19 2.9382816962176048e-18 1.5927653695223069e-18 5295/1912/5718/5689/27161/3725/5684/8841/5290/3667/6801/5682/23035/5468/2065/5525/1459/5700/5707/2146/5978/5526/8535/10273/207/6045/5690/57690/5594/5717/27327/80012/5931/1460/143471/5706/2064/5705/6199/10197/192670/2260/5528/2100/7316/10213/5709/1457/1026/1911/4734/6714/2099/1108/2122/11060/9861/64223/81847/10014/5715/5519/5928/2932/2261/5701/5688/84733/5687/5685/5683/5708/5692/5686/23512/57332/391/5728/5529/2444/5710/6615/5702/192669/3066/3065/7157/1107/23028/8975/3654/7189/5371/23112/5704/6233/5527/2885/2475/55004/7409/7311/2931/5518/1386/1956/5296/4343/8726/2253/648/5694/23466/26523/7874/5781/57521/5693/23608/7314/5879/6015/253260/4193/5515/5516 126 Reovirus R-HSA-5663202 Diseases of signal transduction 163/2430 377/10654 2.5497113507178842e-19 3.702624309303363e-18 2.007095433974719e-18 5295/8454/4000/5718/27044/5689/2963/8805/5434/7276/5440/5684/11052/6464/26127/8841/5290/3667/71/8087/6801/79885/1487/142678/5682/1499/2065/2648/5525/9734/10142/5700/5707/5430/5526/8844/23462/207/5436/7094/1452/5690/5594/5717/6500/409/7414/10533/10013/143471/23385/5706/2064/5705/5441/6199/10197/2260/5438/5431/5528/2100/5435/4686/7316/10213/5709/9978/5433/9611/8546/6774/9759/1026/1024/6714/2099/6934/4609/5664/7415/9861/64223/10014/5715/2962/22938/5519/2932/2261/5701/867/5688/1387/5437/5687/4088/5685/5683/5708/3320/5692/5686/324/2335/2033/408/391/55294/5728/5529/1445/5710/11064/5439/5702/3066/3065/5894/4087/5704/83464/6233/5527/2885/2475/7409/56829/7311/8826/2931/5518/1956/11160/60/5296/4140/7040/9444/2253/3845/55851/51107/5694/3265/369/801/9715/5781/4851/5432/22916/5693/5663/11140/5245/7529/7314/5879/253260/4193/5515/5516 163 Reovirus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 50/2430 67/10654 2.676972512289891e-19 3.845629329483112e-18 2.0846147011380247e-18 5718/5689/5684/11065/5682/246184/5700/7321/5707/991/8697/5690/5717/143471/5706/5705/10197/8881/7316/10213/5709/51433/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/119504/5710/5702/51529/7324/64682/29945/10393/5704/6233/51434/7311/25906/29882/5694/5693/7314/996 50 Reovirus R-HSA-3371556 Cellular response to heat stress 60/2430 89/10654 2.8805481453754345e-19 4.094055661937852e-18 2.219280094085441e-18 23165/3303/6118/4928/81929/5903/7175/9631/7531/1915/5594/3308/10049/348995/10013/545/79023/472/57122/3337/3313/10808/3305/9261/9532/23279/9688/7415/79902/64223/91582/6119/2932/1387/57805/23225/3309/3320/2033/7266/9531/8086/3326/2475/3306/23411/8021/9529/6117/6396/129401/3304/3312/3297/57521/55746/2288/8480/10728/51182 60 Reovirus R-HSA-162909 Host Interactions of HIV factors 76/2430 129/10654 7.801054383312135e-19 1.0970745953794749e-17 5.94695336921745e-18 5718/23165/5689/5905/8945/1173/4928/3837/81929/5684/5903/8065/161/7175/5682/9631/3159/5700/5707/5690/5717/4869/6500/348995/143471/79023/5706/57122/5705/10197/7316/10213/5709/9978/293/920/292/23279/9688/9861/79902/5715/11168/5701/5688/5687/23225/5685/5683/5708/5692/5686/5710/5702/5901/8086/5478/3836/5704/6233/7514/163/1025/7311/8021/6396/129401/375/5694/1104/55746/5693/8480/291/7314/5879 76 Reovirus R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 28/2430 28/10654 9.42386248349353e-19 1.3114875289528495e-17 7.109229592810907e-18 10694/84617/5204/10575/10382/5203/7277/10381/7278/7203/10576/908/10471/6950/7846/113457/347733/7411/81027/10574/10383/60/84790/22948/10693/7280/5201/5202 28 Reovirus R-HSA-69306 DNA Replication 75/2430 127/10654 1.09416556689522e-18 1.507015667393829e-17 8.169136299771148e-18 8454/5718/1017/6118/5689/9134/5684/5000/11065/5682/246184/5700/7321/5707/8317/8697/5690/5717/6500/898/4173/143471/5706/5705/10197/8881/7316/10213/5709/9978/4174/84515/5111/5426/4171/51433/9861/5715/6119/5701/5688/5687/6502/5685/5683/5708/5692/5985/5686/119504/5710/5702/8900/51529/5984/7324/64682/29945/10393/5704/6233/51434/51343/7311/25906/6117/29882/5981/5694/5424/5693/4176/7314/996/56655 75 Reovirus R-HSA-162906 HIV Infection 113/2430 233/10654 3.323412583647257e-18 4.530693073217077e-17 2.455969771803773e-17 6884/5718/23165/5689/5905/8945/1173/4928/2963/3837/6917/81929/5434/5440/5684/5903/8065/161/7175/5682/9631/3159/5700/5707/5430/6874/5436/5690/7520/5717/4869/6500/6749/348995/10015/143471/79023/5706/57122/5705/5441/10197/5438/5431/5435/79720/4686/7316/10213/5709/9978/293/5433/920/292/4836/23279/9688/8148/9861/79902/5715/9525/2962/23327/11168/5701/5688/5437/5687/23225/5685/5683/5708/5692/5686/5710/2068/5439/5702/5901/8086/5478/3836/5704/6233/7514/163/1025/7311/6881/6880/8021/7251/11198/6396/129401/375/5694/6829/1104/51497/2547/1022/5432/55746/22916/5693/8480/291/7314/5879/25920 113 Reovirus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 58/2430 88/10654 5.945781527622808e-18 8.023802142327346e-17 4.349492494422639e-17 5393/5718/3303/5689/5684/5682/5073/5700/5707/3842/207/5690/3184/5717/3315/26986/143471/5706/5705/10197/7534/7538/7316/10213/5709/9261/9861/5715/1432/5701/5688/5687/5685/5683/5708/5692/5686/55802/1981/5710/5702/5704/6233/5580/7514/7311/8021/54464/5600/5694/3304/3312/8570/5693/167227/7529/7314/1994 58 Reovirus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 25/2430 25/10654 8.142921697493836e-17 1.0771231077080955e-15 5.838801592366607e-16 11065/246184/7321/991/8697/8881/7316/4085/51433/119504/51529/7324/64682/29945/10393/4751/6233/51434/701/7311/9184/25906/29882/7314/996 25 Reovirus R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 25/2430 25/10654 8.142921697493836e-17 1.0771231077080955e-15 5.838801592366607e-16 10694/84617/79861/51807/10575/10382/7277/10381/7278/112714/7203/10576/908/6950/7846/113457/347733/10376/81027/10574/10383/84790/22948/10693/7280 25 Reovirus R-HSA-75067 Processing of Capped Intronless Pre-mRNA 27/2430 28/10654 9.124832306894945e-17 1.1941081814381744e-15 6.47294696524948e-16 53981/6635/7884/134353/11051/79869/51585/8106/29894/84967/6637/81608/4686/8189/1477/10978/1478/10898/51692/23283/6636/6634/10914/22916/1479/55339/6628 27 Reovirus R-HSA-9006925 Intracellular signaling by second messengers 134/2430 305/10654 9.206073554500896e-17 1.1941081814381744e-15 6.47294696524948e-16 5295/1912/5718/5689/27161/3725/3838/5684/8841/5290/3667/6801/5682/23035/5468/2065/5525/1459/5700/5707/2146/5978/5526/8535/10273/207/6045/5690/57690/5594/5717/27327/80012/5931/1460/143471/5706/2064/5705/6199/10197/192670/2260/5573/5528/2100/7316/10213/5709/1457/1026/1911/4734/10768/6714/2099/1108/2122/11060/9861/64223/5566/81847/10014/5715/5519/5928/2932/2261/5701/5688/84733/5687/5685/5683/5708/5692/5686/23512/57332/391/5728/5529/2444/5710/6615/5702/192669/3066/3065/7157/1107/23028/8975/3654/7189/5371/23112/5577/5704/6233/5527/2885/5580/2475/55004/7409/7311/2931/5518/1386/1956/5296/5581/4343/8726/2253/648/5694/23466/26523/7874/801/5781/57521/5693/23608/7314/5879/6015/253260/4193/5515/5516 134 Reovirus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 53/2430 80/10654 1.1482602857694042e-16 1.4750728286422347e-15 7.995982556774798e-16 23165/4928/3837/3838/81929/5903/7175/9631/2316/348995/9636/79023/57122/8638/1982/7706/9470/7316/2317/4734/3434/23279/9688/79902/8672/3840/6059/23225/1981/1973/8086/7324/3836/9246/1977/51191/4599/6233/7311/7318/5610/5300/8021/9775/4940/6396/129401/7334/55746/5495/1974/8480/7314 53 Reovirus R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 35/2430 42/10654 1.34756894242823e-16 1.714621054365824e-15 9.29451060040724e-16 2788/10694/6000/54331/59345/1459/8787/10575/10681/51764/1460/94235/7203/10576/908/55970/8786/1457/2792/2793/6950/2785/2783/2784/2782/5082/2786/2771/10574/22948/10693/2791/9628/2790/2787 35 Reovirus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 48/2430 69/10654 1.5757061474658243e-16 1.985984351900322e-15 1.0765499795992921e-15 23165/3303/6118/4928/81929/5903/7175/9631/7531/5594/3308/10049/348995/545/79023/472/57122/3337/3313/10808/3305/9261/9532/23279/9688/79902/91582/6119/2932/57805/23225/3309/7266/9531/8086/3306/23411/8021/9529/6117/6396/129401/3304/3312/3297/55746/8480/51182 48 Reovirus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 28/2430 30/10654 2.5054073323186367e-16 3.1282469121286903e-15 1.6957405259569326e-15 11065/7319/7321/65264/7320/10477/92912/7326/8239/7316/7317/54926/55236/3093/7322/7347/8078/7328/7324/6233/7327/7311/55284/27338/7874/7332/997/7314 28 Reovirus R-HSA-69206 G1/S Transition 73/2430 131/10654 2.650072062924341e-16 3.278237292654555e-15 1.7770463735788953e-15 8454/5718/1017/6118/5689/9134/1019/5684/5000/5682/7027/5700/5707/8317/207/5690/5717/6500/898/5925/4173/5706/5705/10197/4149/7316/10213/5709/4174/891/5753/1876/983/1026/84515/5111/5426/4171/4609/9861/5715/5519/6119/5928/5701/5688/5687/6502/5685/5683/5708/5692/5686/595/5710/5702/3065/8900/5704/6233/7311/5518/6117/5694/7465/1022/5693/7083/4176/7314/5515/5516/56655 73 Reovirus R-HSA-1169408 ISG15 antiviral mechanism 49/2430 72/10654 3.105879226823175e-16 3.806839125720882e-15 2.0635875500283384e-15 23165/4928/3837/3838/81929/5903/7175/9631/348995/9636/79023/57122/1982/7706/9470/7316/2317/4734/3434/23279/9688/79902/8672/3840/23225/1981/1973/8086/7324/3836/9246/1977/51191/4599/6233/7311/7318/5610/5300/8021/9775/6396/129401/7334/55746/5495/1974/8480/7314 49 Reovirus R-HSA-195253 Degradation of beta-catenin by the destruction complex 53/2430 82/10654 5.715122456985416e-16 6.941276002302287e-15 3.762683493211451e-15 8454/5718/5689/8945/5684/1487/5682/1499/5525/5700/5707/5526/1452/5690/5717/6500/143471/5706/5705/10197/5528/7316/10213/5709/9978/6934/9861/5715/5519/2932/5701/5688/5687/5685/5683/5708/5692/5686/324/5529/5710/5702/3065/5704/6233/5527/7311/5518/5694/5693/7314/5515/5516 53 Reovirus R-HSA-71291 Metabolism of amino acids and derivatives 153/2430 372/10654 7.77249357149414e-16 9.35500127163619e-15 5.071100594772848e-15 6158/5718/4967/5689/6138/6144/38/6203/5684/6227/9349/36/4736/1629/6206/6194/6234/1373/6191/6166/6128/5682/51121/6132/6147/6159/9521/6129/5160/6217/5700/3028/5707/2806/191/2639/9255/6222/1743/6176/383/6152/5690/6136/6125/5717/1468/54498/1737/6224/6146/51065/6154/6141/143471/6202/5706/6123/5705/10197/6232/438/6134/60678/6169/6160/6164/5009/6155/10213/5709/6821/6175/6218/79048/9380/10165/79814/6209/6193/8140/6173/6210/6231/6229/11224/6205/6165/9861/6130/5715/6142/6167/6204/5701/5688/6228/58478/23521/5687/116832/4329/1152/5685/5683/5708/7965/8604/5692/5686/5162/140801/6156/6235/6143/5710/6181/6124/5702/26227/54363/6207/6139/6520/5704/6233/7311/6223/25873/1738/3921/6188/6189/6135/6201/6161/5694/9045/6187/2744/6168/5693/6208/2746/6157/6137/6170/200916/6122/6133/7296/593/6230 153 Reovirus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 43/2430 60/10654 1.0682301967897704e-15 1.274246020456369e-14 6.907353152174455e-15 8454/5718/1017/5689/9134/1019/5684/5682/5700/5707/5690/5717/6500/898/5706/5705/10197/7316/10213/5709/5753/1026/9861/5715/5701/5688/5687/6502/5685/5683/5708/5692/5686/595/5710/5702/8900/5704/6233/7311/5694/5693/7314 43 Reovirus R-HSA-8878166 Transcriptional regulation by RUNX2 68/2430 121/10654 1.5684274072446118e-15 1.8543531115741607e-14 1.0051961399015305e-14 8454/57154/5718/8493/5689/1019/5684/8841/5682/5700/5707/23462/10273/207/5690/5594/5717/6500/5925/100526737/10013/143471/3958/5706/5705/10197/7316/10213/5709/9978/891/11059/9759/983/1026/10413/6714/2099/9861/5715/2932/5701/5688/5687/6502/2908/5685/5683/5708/5692/5686/595/55294/5710/5702/861/5704/6233/7525/7311/367/860/10432/581/5694/133522/5693/7314 68 Reovirus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 23/2430 23/10654 1.5889708425536166e-15 1.8621623207470454e-14 1.0094293071808755e-14 11065/246184/7321/991/8697/8881/7316/891/983/51433/119504/51529/7324/64682/29945/10393/6233/51434/7311/25906/29882/7314/996 23 Reovirus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 45/2430 65/10654 1.8748218275109005e-15 2.1780538796126637e-14 1.180665828217391e-14 10450/6118/6917/5434/5440/100534599/2074/27339/5430/5436/7515/5441/5438/5431/8450/5435/7316/9978/5433/5111/5426/6119/5437/1161/1642/5985/2033/2068/5439/5984/6233/7311/56949/9716/6117/5981/7874/57461/5424/1022/5432/91603/7314/8451/56655 45 Reovirus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 90/2430 182/10654 2.0667260318217227e-15 2.3802982573395012e-14 1.2902971959104765e-14 1912/23165/7020/23468/7150/5905/4928/81929/5893/5903/7175/1487/55143/83746/9631/5468/1029/7486/8535/6045/9212/3619/4869/80012/7153/10274/348995/51602/79023/6613/57122/10735/3183/332/5885/1655/4792/3190/9759/1911/6790/641/5111/2099/23279/9688/79902/9656/7341/1387/84733/10521/23225/2908/2033/23512/165918/8243/9126/57332/142/7428/3066/3065/7157/1107/1069/8086/668/7329/5371/8924/672/10155/367/7155/8021/9641/6117/7690/6294/6396/648/129401/7703/11315/55746/8480/6015/4193 90 Reovirus R-HSA-453279 Mitotic G1-G1/S phases 78/2430 149/10654 2.8334694200584782e-15 3.235483030083869e-14 1.75387041025662e-14 8454/5718/1017/6118/5689/9134/1019/5684/5000/5682/1029/7027/5700/5707/8317/207/5690/5717/6500/7153/898/5925/4173/5706/5705/10197/4149/7316/10213/5709/4174/891/5753/1876/983/1026/84515/5111/5426/6714/4171/4609/9861/5715/5519/6119/5928/5701/5688/5687/6502/5685/5683/5708/5692/5686/595/5710/5702/3065/5520/8900/5704/6233/7311/5518/6117/5694/7465/1022/1859/5693/7083/4176/7314/5515/5516/56655 78 Reovirus R-HSA-9013694 Signaling by NOTCH4 52/2430 82/10654 3.5141863764975663e-15 3.978773727966736e-14 2.1567887841483726e-14 8454/5718/5689/5684/5682/2648/5700/5707/23462/207/5690/5717/6500/23385/5706/5705/10197/7534/7316/10213/5709/9978/5664/9861/5715/22938/5701/5688/1387/5687/4088/5685/5683/5708/59/5692/5686/2033/55294/5710/5702/5704/83464/6233/7311/55851/51107/5694/4851/5693/5663/7314 52 Reovirus R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 38/2430 51/10654 6.156362469779331e-15 6.911680890441333e-14 3.746640760024927e-14 84617/79861/11258/1783/51807/10382/5050/347688/55860/830/7277/10381/7278/112714/1780/5048/1781/8655/1639/832/10121/5870/7846/113457/2590/347733/51560/10376/51143/10540/81027/10383/84790/5049/140735/7280/829/1778 38 Reovirus R-HSA-389977 Post-chaperonin tubulin folding pathway 22/2430 22/10654 7.015754982570598e-15 7.810873880595266e-14 4.234069673691729e-14 402/84617/79861/51807/10382/6903/7277/10381/7278/112714/6902/6905/1155/7846/113457/347733/10376/81027/10383/84790/7280/6904 22 Reovirus R-HSA-2990846 SUMOylation 91/2430 188/10654 7.682994783030962e-15 8.483042173660633e-14 4.598434459091171e-14 1912/23165/7020/23468/7150/5905/4928/81929/5893/5903/7175/1487/55143/83746/9631/5468/1029/7486/8535/6045/9212/3619/4869/80012/7153/10274/348995/51602/79023/6613/57122/10735/3183/332/5885/1655/4792/3190/9759/1911/6790/641/5111/2099/23279/9688/79902/9656/7341/1387/84733/10521/23225/2908/59343/2033/23512/165918/8243/9126/57332/142/7428/3066/3065/7157/1107/1069/8086/668/7329/5371/8924/672/10155/367/7155/8021/9641/6117/7690/6294/6396/648/129401/7703/11315/55746/8480/6015/4193 91 Reovirus R-HSA-6798695 Neutrophil degranulation 183/2430 480/10654 7.751407739849727e-15 8.488426836425603e-14 4.6013533434138157e-14 10450/5869/2717/25801/10694/5718/2512/3303/58485/9798/23352/1727/5689/8804/2934/3837/8514/10890/7276/161/5036/8621/5005/9218/960/4332/56888/1938/1511/5657/57826/1915/8635/3107/5707/5315/203068/3848/9761/1650/23197/383/387921/1991/10120/5594/6317/7520/54472/8836/5717/3577/2215/5211/6727/55860/7414/1460/2760/10533/29108/23385/3958/79980/4257/6280/10577/5912/2517/6993/11240/10213/5709/10576/5329/6278/2896/5611/8655/84061/5834/527/1315/6279/2799/9588/29952/4069/353/7415/9861/3074/5870/410/3043/4353/2548/1432/411/5701/3920/6836/140885/2171/5476/1832/2821/5553/5683/55832/5708/3320/55313/201294/5686/3615/388697/2588/23593/4311/391/3614/3728/80142/175/2444/51143/10043/5702/6386/4125/566/5478/23071/51552/10075/5878/2683/56729/10487/5473/3326/5580/6709/10857/55004/10097/93100/47/8826/81567/302/10383/387/5049/6036/4282/3608/80184/2720/3304/3312/2040/2547/10493/387263/10970/2990/5663/2665/7879/1075/671/1654/114790/2519/6037/5879/51316/2950/1778/718/30 183 Reovirus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 40/2430 56/10654 1.2961075594146882e-14 1.4078046336406694e-13 7.631339331427519e-14 5718/3303/5689/5684/5682/5700/5707/5690/3184/5717/3315/26986/143471/5706/5705/10197/7316/10213/5709/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/1981/5710/5702/5704/6233/7311/5694/3304/3312/5693/7314 40 Reovirus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 49/2430 77/10654 1.8048462831632642e-14 1.9445763179888072e-13 1.0541037714909386e-13 1912/23165/4928/81929/5893/5903/7175/9631/1029/7486/8535/6045/80012/10274/348995/79023/6613/57122/10735/5885/1911/641/23279/9688/79902/9656/7341/84733/23225/165918/8243/9126/57332/142/1069/8086/7329/5371/8924/672/8021/6117/6396/648/129401/7703/55746/8480/6015 49 Reovirus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 52/2430 85/10654 3.020342489393241e-14 3.228142052663496e-13 1.7498910591179365e-13 8454/5718/1017/5689/9134/1019/5684/5682/7027/5700/5707/207/5690/5717/6500/898/5925/5706/5705/10197/4149/7316/10213/5709/5753/1026/4609/9861/5715/5928/5701/5688/5687/6502/5685/5683/5708/5692/5686/595/5710/5702/8900/5704/6233/51343/7311/5694/7465/1022/5693/7314 52 Reovirus R-HSA-6782135 Dual incision in TC-NER 44/2430 66/10654 3.2684227796741956e-14 3.465565740987877e-13 1.8785922075320354e-13 10450/6118/6917/5434/5440/100534599/2074/27339/5430/5436/5441/5438/5431/8450/5435/7316/9978/5433/5111/5426/6119/5437/1161/1642/5985/2033/2068/5439/5984/6233/7311/56949/9716/6117/5981/7874/57461/5424/1022/5432/91603/7314/8451/56655 44 Reovirus R-HSA-5696398 Nucleotide Excision Repair 62/2430 111/10654 4.103982029515907e-14 4.297095087605178e-13 2.329342436394865e-13 10450/6118/6917/5434/5440/100534599/2074/27339/5430/83444/5436/7515/6613/5441/7336/86/5438/5431/8450/5435/54778/7316/9978/5433/5111/5426/1643/10980/6119/7341/5437/1161/1642/54617/5985/2033/142/2068/5439/10987/5984/1069/7329/6233/7311/56949/60/8533/8607/9716/6117/7334/5981/7874/57461/5424/1022/5432/91603/7314/8451/56655 62 Reovirus R-HSA-8941858 Regulation of RUNX3 expression and activity 39/2430 55/10654 4.116977329442087e-14 4.297095087605178e-13 2.329342436394865e-13 57154/5718/5689/5684/5682/1029/5700/5707/5690/5717/5706/5705/10197/64750/7316/10213/5709/6714/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/2033/5710/5702/5704/6233/7311/7040/5694/5693/7314/4193 39 Reovirus R-HSA-69202 Cyclin E associated events during G1/S transition 51/2430 83/10654 4.151426011925921e-14 4.299461358087621e-13 2.3306251295022713e-13 8454/5718/1017/5689/9134/1019/5684/5682/7027/5700/5707/207/5690/5717/6500/898/5925/5706/5705/10197/4149/7316/10213/5709/5753/1026/4609/9861/5715/5928/5701/5688/5687/6502/5685/5683/5708/5692/5686/595/5710/5702/8900/5704/6233/7311/5694/7465/1022/5693/7314 51 Reovirus R-HSA-8948751 Regulation of PTEN stability and activity 45/2430 69/10654 5.6563845354404814e-14 5.793711703214534e-13 3.1406190134034027e-13 5718/5689/5684/5682/1459/5700/5707/10273/207/5690/5717/1460/143471/5706/5705/10197/7316/10213/5709/1457/4734/11060/9861/81847/5715/5701/5688/5687/5685/5683/5708/5692/5686/5728/2444/5710/5702/8975/5704/6233/7311/5694/5693/23608/7314 45 Reovirus R-HSA-8878159 Transcriptional regulation by RUNX3 56/2430 96/10654 5.6809598287507775e-14 5.793711703214534e-13 3.1406190134034027e-13 57154/5718/5689/5684/5682/1499/2648/1029/5700/5707/5690/5717/5706/5705/10197/64750/6696/7316/10213/5709/9759/1026/10413/6714/6934/4609/9861/5715/22938/5701/5688/1387/5687/4088/5685/5683/5708/5692/5686/2033/595/5710/5702/7157/861/5704/6233/7311/7040/3845/5694/4851/5693/3676/7314/4193 56 Reovirus R-HSA-4570464 SUMOylation of RNA binding proteins 35/2430 47/10654 7.583929618445728e-14 7.675856038063253e-13 4.1608800458458216e-13 1912/23165/4928/81929/5903/7175/9631/8535/6045/80012/348995/51602/79023/6613/57122/3183/3190/1911/23279/9688/79902/7341/84733/23225/57332/8086/7329/8021/6396/648/129401/7703/55746/8480/6015 35 Reovirus R-HSA-5687128 MAPK6/MAPK4 signaling 53/2430 89/10654 8.292881309236353e-14 8.330292803864488e-13 4.5156330358168663e-13 5718/5689/27161/3725/5684/5682/5700/10642/5707/5690/57690/5717/3315/27327/143471/5706/5705/10197/3337/192670/7316/10213/5709/983/5597/4609/9861/5566/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/192669/998/8556/23112/5704/6233/7514/7311/4343/5694/26523/5693/7314/5879 53 Reovirus R-HSA-168325 Viral Messenger RNA Synthesis 33/2430 43/10654 8.988384659789717e-14 8.961553660805271e-13 4.857822974026178e-13 23165/4928/2963/81929/5434/5440/5903/7175/9631/5430/5436/348995/79023/57122/5441/5438/5431/5435/5433/23279/9688/79902/2962/5437/23225/5439/8086/8021/6396/129401/5432/55746/8480 33 Reovirus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 38/2430 54/10654 1.2980138997185382e-13 1.2751077720764464e-12 6.912024481473331e-13 8454/5718/5689/5684/5682/5700/5707/5690/5717/6500/143471/5706/5705/10197/7316/10213/5709/9978/6790/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/5704/6233/7311/23194/5694/5693/7314 38 Reovirus R-HSA-9604323 Negative regulation of NOTCH4 signaling 38/2430 54/10654 1.2980138997185382e-13 1.2751077720764464e-12 6.912024481473331e-13 8454/5718/5689/5684/5682/5700/5707/207/5690/5717/6500/5706/5705/10197/7534/7316/10213/5709/9978/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/55294/5710/5702/5704/6233/7311/5694/5693/7314 38 Reovirus R-HSA-3858494 Beta-catenin independent WNT signaling 74/2430 146/10654 1.3101708245233833e-13 1.2776556361775476e-12 6.925835783880812e-13 2788/57154/5718/5689/27161/1173/5684/161/54331/5682/1499/59345/4772/5700/5707/5690/57690/5717/10681/27327/409/51764/94235/143471/5706/5705/10197/192670/64750/7316/10213/5709/55970/5216/2792/6934/9861/5715/5701/5688/2793/5687/5685/5683/5708/5692/5686/2785/2783/23002/2784/5710/2782/5702/192669/2786/23112/5704/6233/163/7311/1213/387/4343/3845/5694/26523/801/5693/2791/7314/5879/2790/2787 74 Reovirus R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 20/2430 20/10654 1.3663848581432056e-13 1.3133022809203762e-12 7.119066886804432e-13 11065/246184/7321/991/8697/8881/4085/51433/119504/51529/7324/64682/29945/10393/51434/701/9184/25906/29882/996 20 Reovirus R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 20/2430 20/10654 1.3663848581432056e-13 1.3133022809203762e-12 7.119066886804432e-13 11065/246184/7321/991/8697/8881/4085/51433/119504/51529/7324/64682/29945/10393/51434/701/9184/25906/29882/996 20 Reovirus R-HSA-69615 G1/S DNA Damage Checkpoints 44/2430 68/10654 1.6431459264918998e-13 1.5680306841379843e-12 8.499882687416744e-13 5718/1017/5689/9134/5684/5682/1029/5700/5707/5690/5717/898/11200/143471/5706/472/5705/10197/7316/10213/5709/1026/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/1111/5702/7157/8900/5704/6233/7311/5694/5693/7314/4193 44 Reovirus R-HSA-8939902 Regulation of RUNX2 expression and activity 46/2430 73/10654 1.9523470703003953e-13 1.8498834651924315e-12 1.002773261938538e-12 8454/57154/5718/5689/5684/5682/5700/5707/10273/5690/5717/6500/143471/5706/5705/10197/7316/10213/5709/9978/11059/2099/9861/5715/2932/5701/5688/5687/6502/2908/5685/5683/5708/5692/5686/55294/5710/5702/5704/6233/7311/860/5694/133522/5693/7314 46 Reovirus R-HSA-69563 p53-Dependent G1 DNA Damage Response 43/2430 66/10654 2.1730737319965736e-13 2.0302283258373586e-12 1.1005334763442345e-12 5718/1017/5689/9134/5684/5682/1029/5700/5707/5690/5717/898/11200/143471/5706/472/5705/10197/7316/10213/5709/1026/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/7157/8900/5704/6233/7311/5694/5693/7314/4193 43 Reovirus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 43/2430 66/10654 2.1730737319965736e-13 2.0302283258373586e-12 1.1005334763442345e-12 5718/1017/5689/9134/5684/5682/1029/5700/5707/5690/5717/898/11200/143471/5706/472/5705/10197/7316/10213/5709/1026/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/7157/8900/5704/6233/7311/5694/5693/7314/4193 43 Reovirus R-HSA-68949 Orc1 removal from chromatin 45/2430 71/10654 2.634120578476172e-13 2.4438785366973378e-12 1.3247623961926945e-12 8454/5718/1017/5689/5684/5000/5682/5700/5707/5690/5717/6500/4173/143471/5706/5705/10197/7316/10213/5709/9978/4174/84515/4171/9861/5715/5701/5688/5687/6502/5685/5683/5708/5692/5686/5710/5702/8900/5704/6233/7311/5694/5693/4176/7314 45 Reovirus R-HSA-194315 Signaling by Rho GTPases 171/2430 455/10654 2.7351998683490783e-13 2.520156568354737e-12 1.3661107146454926e-12 220134/5905/55839/11130/84617/4928/79682/81929/5590/5903/1072/10403/79861/54908/71/6249/55143/1499/55055/25936/5525/9735/7531/80776/4690/1783/1058/10093/991/10006/401541/79019/5526/51807/2316/7532/10971/348235/80152/4771/10382/9212/389/5594/1063/347688/29127/8379/3798/3619/10627/1894/79172/1080/2810/147841/7277/348995/23421/55920/79023/10381/57122/79980/64105/6280/7278/6232/7534/332/112714/1780/6242/23122/5528/3688/5048/1781/5501/57405/8655/4085/5585/5216/10552/10094/6279/6714/23279/55166/79902/3796/54821/5519/9183/1432/81565/2491/1062/699/7846/999/113457/89953/396/347733/22919/1060/91687/79003/10376/391/23002/5529/11113/51143/998/81027/23028/83540/11004/90627/5527/2885/7410/10096/5580/701/10097/7409/9055/7514/23380/9184/9928/367/8826/29941/5518/3799/10383/54820/5347/387/57551/60/5296/5300/84790/84643/6396/5600/23332/25909/801/64946/9793/10726/10109/5586/81930/55746/2665/140735/7280/7529/5879/5515/1778/5516/10672 171 Reovirus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 32/2430 42/10654 3.0612267851989816e-13 2.8012321815245472e-12 1.5184744255348949e-12 23165/53981/4928/81929/5903/7175/9631/7884/29894/348995/79023/57122/81608/4686/8189/23279/9688/79902/10898/23225/10189/10482/51692/8086/1977/8021/6396/129401/55746/22916/8480/55339 32 Reovirus R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 38/2430 55/10654 3.2791912136846807e-13 2.9802717425052606e-12 1.6155270712603367e-12 8454/5718/5689/8945/5684/5682/5700/5707/991/5690/5717/6500/143471/5706/5705/10197/7316/10213/5709/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/5704/6233/51343/7311/5694/5693/7314 38 Reovirus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 48/2430 79/10654 4.27984213500912e-13 3.863425062413637e-12 2.094261300772599e-12 10450/6118/6917/5434/5440/100534599/2074/27339/5430/5436/7515/5441/5438/5431/8450/5435/7316/9978/5433/5111/5426/10980/6119/5437/1161/1642/5985/2033/2068/5439/10987/5984/6233/7311/56949/8533/9716/6117/5981/7874/57461/5424/1022/5432/91603/7314/8451/56655 48 Reovirus R-HSA-5610783 Degradation of GLI2 by the proteasome 40/2430 60/10654 4.845670789611419e-13 4.3158774499472375e-12 2.3395238619316885e-12 8454/5718/5689/8945/5684/5682/5700/5707/1452/5690/5717/6500/143471/5706/5705/10197/7316/10213/5709/9978/9861/5566/5715/2932/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/5704/6233/7311/5694/5693/7314 40 Reovirus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 40/2430 60/10654 4.845670789611419e-13 4.3158774499472375e-12 2.3395238619316885e-12 8454/5718/5689/8945/5684/5682/5700/5707/1452/5690/5717/6500/143471/5706/5705/10197/7316/10213/5709/9978/9861/5566/5715/2932/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/5704/6233/7311/5694/5693/7314 40 Reovirus R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 19/2430 19/10654 6.027168380901302e-13 5.262939187505973e-12 2.8529011668800106e-12 11065/246184/7321/991/8697/8881/51433/119504/51529/8556/7324/64682/29945/10393/51434/51343/25906/29882/996 19 Reovirus R-HSA-176412 Phosphorylation of the APC/C 19/2430 19/10654 6.027168380901302e-13 5.262939187505973e-12 2.8529011668800106e-12 11065/246184/7321/8697/8881/891/983/51433/119504/51529/7324/64682/29945/10393/51434/25906/5347/29882/996 19 Reovirus R-HSA-77595 Processing of Intronless Pre-mRNAs 19/2430 19/10654 6.027168380901302e-13 5.262939187505973e-12 2.8529011668800106e-12 53981/11051/79869/51585/8106/29894/81608/4686/8189/1477/10978/1478/10898/51692/23283/10914/22916/1479/55339 19 Reovirus R-HSA-8856688 Golgi-to-ER retrograde transport 68/2430 133/10654 7.564744972175146e-13 6.562661871964933e-12 3.5574467128205746e-12 22820/84617/79861/11258/1783/51807/10382/5050/347688/29127/3798/5861/55860/830/7277/10381/55605/7278/112714/1780/9554/5048/1781/8655/1315/23303/1639/832/10121/3796/5870/9183/10112/11316/1062/6836/7846/113457/89953/2590/547/347733/51560/8729/10376/10972/51143/1314/10540/81027/381/11004/9276/3833/3799/10383/84790/84643/378/5049/375/22920/81930/140735/7280/54732/829/1778 68 Reovirus R-HSA-429914 Deadenylation-dependent mRNA decay 38/2430 56/10654 7.96660261446988e-13 6.8666974793108126e-12 3.7222564337896615e-12 5393/1656/9924/80153/5073/27257/27258/4849/25804/51690/4850/255967/26986/10605/28960/9337/11157/57819/25904/246175/4848/23019/23658/55802/1981/1973/10767/1977/1975/55571/9775/54464/6499/57472/85456/29883/1974/167227 38 Reovirus R-HSA-1234174 Cellular response to hypoxia 46/2430 75/10654 8.127010107620878e-13 6.960054810116342e-12 3.772862991931959e-12 5718/5689/5684/5682/112399/5700/7321/5707/84962/5690/5717/3091/143471/5706/5705/10197/7323/7316/10213/5709/9978/9861/7322/5715/5701/5688/1387/5687/5685/5683/5708/5692/5686/2033/5710/25994/7428/5702/8453/5704/6233/7311/55662/5694/5693/7314 46 Reovirus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 37/2430 54/10654 1.0073809774370098e-12 8.572362967234683e-12 4.646852916370518e-12 10450/6917/5434/5440/100534599/2074/27339/5430/5436/5441/5438/5431/8450/5435/7316/9978/5433/10980/5437/1161/1642/2033/2068/5439/10987/6233/7311/56949/8533/9716/7874/57461/1022/5432/91603/7314/8451 37 Reovirus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 31/2430 41/10654 1.0349109385032334e-12 8.750892492660252e-12 4.743629085211356e-12 23165/53981/4928/81929/5903/7175/9631/29894/348995/79023/57122/81608/4686/8189/23279/9688/79902/10898/23225/10189/10482/51692/8086/1977/8021/6396/129401/55746/22916/8480/55339 31 Reovirus R-HSA-180534 Vpu mediated degradation of CD4 36/2430 52/10654 1.2601400545506238e-12 1.0522169455497709e-11 5.703791825860718e-12 5718/5689/8945/5684/5682/5700/5707/5690/5717/6500/143471/5706/5705/10197/7316/10213/5709/920/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/5704/6233/7311/5694/5693/7314 36 Reovirus R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 36/2430 52/10654 1.2601400545506238e-12 1.0522169455497709e-11 5.703791825860718e-12 5718/5689/1019/5684/5682/5700/5707/5690/5717/143471/5706/5705/10197/7316/10213/5709/9861/5715/2932/5701/5688/5687/5685/5683/5708/5692/5686/595/5710/5702/5704/6233/7311/5694/5693/7314 36 Reovirus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 42/2430 66/10654 1.353300880045003e-12 1.1229875625715057e-11 6.087420761496973e-12 5718/5689/5684/5682/112399/5700/7321/5707/84962/5690/5717/3091/143471/5706/5705/10197/7323/7316/10213/5709/9978/9861/7322/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/7428/5702/8453/5704/6233/7311/5694/5693/7314 42 Reovirus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 39/2430 59/10654 1.4373442099505579e-12 1.1853653484530526e-11 6.42555436287189e-12 8454/5718/5689/8945/5684/5682/5700/5707/5690/9039/5717/6500/143471/5706/5705/10197/7316/10213/5709/9861/5715/5701/5688/5687/23291/5685/5683/5708/5692/5686/5710/5702/9040/5704/6233/7311/5694/5693/7314 39 Reovirus R-HSA-69541 Stabilization of p53 38/2430 57/10654 1.8663925274511118e-12 1.5297548568556353e-11 8.292399476179302e-12 5718/5689/5684/5682/1029/5700/5707/5690/5717/11200/143471/5706/472/5705/10197/7316/10213/5709/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/7157/5704/6233/7311/5694/5693/7314/4193 38 Reovirus R-HSA-6803529 FGFR2 alternative splicing 23/2430 26/10654 1.9840460777681506e-12 1.6162716828647863e-11 8.761384476922256e-12 2963/5434/5440/23543/5430/5436/3178/5441/5438/5431/5435/4686/5433/3185/2962/5437/4670/5439/3187/7073/5432/22916/5725 23 Reovirus R-HSA-190840 Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane 18/2430 18/10654 2.657751363982848e-12 2.1519732256249003e-11 1.1665281903797125e-11 84617/79861/51807/10382/347688/7277/2697/10381/7278/112714/7846/113457/347733/10376/81027/10383/84790/7280 18 Reovirus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 39/2430 60/10654 3.2067874532165965e-12 2.5654299625732772e-11 1.3906522330999168e-11 8454/5718/5689/8945/5684/5682/5700/5707/5690/9039/5717/6500/143471/5706/5705/10197/7316/10213/5709/9861/5715/5701/5688/5687/23291/5685/5683/5708/5692/5686/5710/5702/9040/5704/6233/7311/5694/5693/7314 39 Reovirus R-HSA-5610780 Degradation of GLI1 by the proteasome 39/2430 60/10654 3.2067874532165965e-12 2.5654299625732772e-11 1.3906522330999168e-11 8454/5718/5689/8945/5684/5682/5700/5707/5690/5717/6500/143471/5706/5705/10197/7316/10213/5709/9978/9861/5566/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/83737/5704/6233/7311/5694/5693/7314 39 Reovirus R-HSA-5626467 RHO GTPases activate IQGAPs 26/2430 32/10654 3.82843189431229e-12 3.0445148873816784e-011 1.65035159353813e-11 84617/79861/71/6249/1499/51807/10382/347688/7277/10381/7278/112714/7846/999/113457/347733/10376/998/81027/8826/10383/60/84790/801/7280/5879 26 Reovirus R-HSA-5607764 CLEC7A (Dectin-1) signaling 55/2430 101/10654 4.513716113919773e-12 3.568239484140129e-11 1.9342489482259758e-11 8454/5718/5689/8945/5684/4773/5682/4772/5700/7321/5707/5690/9039/5717/6500/29108/143471/5706/5705/841/10197/7316/10213/5709/7335/4792/6850/10768/6714/9861/7322/5715/5701/5688/5687/23291/5685/5683/5708/5692/5686/5710/5702/9040/7189/5704/6233/5580/7311/7334/5694/801/5693/997/7314 55 Reovirus R-HSA-4615885 SUMOylation of DNA replication proteins 32/2430 45/10654 7.25042305173159e-12 5.6979795277137666e-11 3.088725114298039e-11 23165/7150/5905/4928/81929/5903/7175/55143/9631/9212/3619/7153/348995/79023/6613/57122/332/6790/5111/23279/9688/79902/7341/23225/8086/7329/7155/8021/6396/129401/55746/8480 32 Reovirus R-HSA-429947 Deadenylation of mRNA 22/2430 25/10654 7.75972449557449e-12 6.062568377828958e-11 3.286359158482763e-11 9924/5073/4849/4850/255967/26986/10605/9337/25904/246175/4848/23019/1981/1973/1977/1975/55571/9775/57472/85456/29883/1974 22 Reovirus R-HSA-5610787 Hedgehog 'off' state 59/2430 113/10654 8.016712399995836e-12 6.226934747903742e-11 3.375457852629825e-11 8454/5718/5689/8945/84617/5684/5682/54903/5700/5707/1452/5690/10382/5717/6500/7277/143471/5706/10381/5705/10197/7278/5573/7316/10213/5709/9978/9861/5566/5715/2932/5701/5688/5687/7846/113457/5685/5683/347733/5708/5692/5686/10376/5710/5702/81027/83737/5577/5704/6233/7311/10383/23322/84790/5694/8481/5693/7280/7314 59 Reovirus R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 35/2430 52/10654 9.266333493716677e-12 7.033989515684931e-11 3.812941054830785e-11 5718/5689/5684/5682/5700/5707/5690/5717/143471/5706/472/5705/10197/7316/10213/5709/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/7157/5704/6233/7311/5694/5693/7314 35 Reovirus R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 35/2430 52/10654 9.266333493716677e-12 7.033989515684931e-11 3.812941054830785e-11 5718/5689/5684/5682/5700/5707/5690/5717/11200/143471/5706/5705/10197/7316/10213/5709/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/1111/5702/5704/6233/7311/5694/5693/7314 35 Reovirus R-HSA-69610 p53-Independent DNA Damage Response 35/2430 52/10654 9.266333493716677e-12 7.033989515684931e-11 3.812941054830785e-11 5718/5689/5684/5682/5700/5707/5690/5717/11200/143471/5706/5705/10197/7316/10213/5709/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/1111/5702/5704/6233/7311/5694/5693/7314 35 Reovirus R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 35/2430 52/10654 9.266333493716677e-12 7.033989515684931e-11 3.812941054830785e-11 5718/5689/5684/5682/5700/5707/5690/5717/11200/143471/5706/5705/10197/7316/10213/5709/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/1111/5702/5704/6233/7311/5694/5693/7314 35 Reovirus R-HSA-69481 G2/M Checkpoints 77/2430 168/10654 2.8653941485928685e-11 2.1628059788248994e-10 1.1724003414997879e-10 5718/1017/6118/5689/5684/5000/5682/5883/7531/51512/5700/7486/5707/10111/7532/8317/10971/5690/5717/2810/4173/11200/143471/545/5706/9133/472/5705/10197/7336/7534/580/11073/7316/10213/5709/4174/891/983/84515/641/4171/9861/5715/9656/6119/7341/5701/5688/5687/5685/5683/5708/5692/5985/5686/165918/5710/1111/5702/7157/5984/8924/5704/6233/672/7311/79184/7156/6117/7334/5694/7465/5693/4176/7529/7314 77 Reovirus R-HSA-190872 Transport of connexons to the plasma membrane 18/2430 19/10654 3.964837283005188e-11 2.9758553989297367e-10 1.6131330873492426e-10 84617/79861/51807/10382/347688/7277/2697/10381/7278/112714/7846/113457/347733/10376/81027/10383/84790/7280 18 Reovirus R-HSA-109581 Apoptosis 80/2430 178/10654 4.000547029978683e-11 2.9858831463974975e-10 1.618568865995492e-10 4000/5718/5689/2934/3837/1676/5684/22985/5682/1499/4976/7531/1029/7027/5700/5707/7532/207/10971/5690/5594/10059/5717/2810/143471/5706/1829/5705/841/10197/7534/9500/7316/10213/5709/8655/7082/6774/54205/5339/4836/9861/5715/8428/5701/5688/5687/1832/999/598/5685/5683/5708/5692/5686/708/324/4137/5710/3002/5702/7157/8626/4001/3836/5704/6233/5580/6709/7311/8837/581/5599/8717/7431/5694/5693/140735/7529/7314 80 Reovirus R-HSA-5633007 Regulation of TP53 Activity 74/2430 160/10654 4.092195115109731e-11 3.020731829183661e-10 1.6374594220598477e-10 6884/1017/6118/5883/1029/1459/7486/10111/6874/8445/207/22974/9212/5931/1460/6749/11200/545/472/580/11073/7316/80196/84289/1457/54971/983/6790/641/1108/8148/64223/5519/6119/5928/1432/6794/5985/2033/1111/3066/3065/7157/1107/8900/5984/91875/8626/5371/6233/5527/2475/672/7311/6881/5562/5518/6880/10419/5300/7156/6117/11198/5600/7874/1020/26155/26013/10919/7314/253260/4193/5515/5516 74 Reovirus R-HSA-5678895 Defective CFTR causes cystic fibrosis 38/2430 61/10654 4.092458541034751e-11 3.020731829183661e-10 1.6374594220598477e-10 5718/5689/5684/5682/5700/5707/6048/5690/5717/1080/143471/5706/5705/10197/7316/10213/5709/7415/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/10613/5704/6233/7311/11160/5694/5693/7314 38 Reovirus R-HSA-180585 Vif-mediated degradation of APOBEC3G 35/2430 54/10654 4.7338272185362004e-11 3.4749412988815184e-10 1.8836744513319292e-10 5718/5689/5684/8065/5682/5700/5707/5690/5717/143471/5706/5705/10197/7316/10213/5709/9978/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/5704/6233/7311/5694/5693/7314 35 Reovirus R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 33/2430 50/10654 8.215694137155411e-11 5.997905665158268e-10 3.251307199518506e-10 5718/5689/5684/5682/5700/5707/5690/5717/143471/5706/5705/10197/7316/10213/5709/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/5704/6233/7311/5694/5693/7314 33 Reovirus R-HSA-4641257 Degradation of AXIN 35/2430 55/10654 1.0172108702535119e-10 7.385835449232021e-10 4.003667498480641e-10 5718/5689/5684/5682/5700/5707/5690/5717/143471/5706/5705/10197/64750/7316/10213/5709/9861/81847/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/5704/6233/7311/5694/5693/7314 35 Reovirus R-HSA-5357801 Programmed Cell Death 80/2430 181/10654 1.1067634527506829e-10 7.992626880404932e-10 4.3325932033710943e-10 4000/5718/5689/2934/3837/1676/5684/22985/5682/1499/4976/7531/1029/7027/5700/5707/7532/207/10971/5690/5594/10059/5717/2810/143471/5706/1829/5705/841/10197/7534/9500/7316/10213/5709/8655/7082/6774/54205/5339/4836/9861/5715/8428/5701/5688/5687/1832/999/598/5685/5683/5708/5692/5686/708/324/4137/5710/3002/5702/7157/8626/4001/3836/5704/6233/5580/6709/7311/8837/581/5599/8717/7431/5694/5693/140735/7529/7314 80 Reovirus R-HSA-169911 Regulation of Apoptosis 34/2430 53/10654 1.364463284062062e-10 9.800661008101691e-10 5.312681038113744e-10 5718/5689/5684/5682/4976/5700/5707/5690/5717/143471/5706/5705/10197/7316/10213/5709/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/5704/6233/7311/5694/5693/7314 34 Reovirus R-HSA-8964315 G beta:gamma signalling through BTK 17/2430 18/10654 1.657046846060513e-10 1.1838580675598103e-9 6.417383788852422e-10 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Reovirus R-HSA-162587 HIV Life Cycle 70/2430 152/10654 1.7463643035043558e-10 1.2410333561073508e-9 6.727316017978706e-10 6884/23165/5905/4928/2963/6917/81929/5434/5440/5903/7175/9631/3159/5430/6874/5436/7520/6749/348995/10015/79023/57122/5441/5438/5431/5435/79720/4686/7316/5433/920/4836/23279/9688/8148/79902/9525/2962/23327/11168/5437/23225/2068/5439/5901/8086/5478/3836/6233/7514/1025/7311/6881/6880/8021/7251/11198/6396/129401/6829/1104/51497/2547/1022/5432/55746/22916/8480/7314/25920 70 Reovirus R-HSA-168253 Host Interactions with Influenza Factors 29/2430 42/10654 2.218501763123924e-10 1.568210770123578e-9 8.50085888626711e-10 23165/4928/3837/3838/81929/5903/7175/9631/8106/348995/9636/79023/57122/293/23279/9688/79902/10898/3840/23225/8086/3836/5610/8021/7040/6396/129401/55746/8480 29 Reovirus R-HSA-8964616 G beta:gamma signalling through CDC42 18/2430 20/10654 3.1135987851854266e-10 2.1893515668461736e-9 1.1867900078712317e-9 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/998/2786/2791/2790/2787 18 Reovirus R-HSA-69002 DNA Replication Pre-Initiation 46/2430 85/10654 3.3570919890580655e-10 2.3482067525557986e-9 1.2729012336577287e-9 5718/1017/6118/5689/5684/5000/5682/5700/5707/8317/5690/5717/4173/143471/5706/5705/10197/7316/10213/5709/4174/84515/5426/4171/9861/5715/6119/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/5704/6233/7311/6117/5694/5693/4176/7314/56655 46 Reovirus R-HSA-1169091 Activation of NF-kappaB in B cells 39/2430 67/10654 4.1744566493805153e-10 2.9047260851939416e-9 1.574575753713703e-9 8454/5718/5689/8945/5684/5966/5682/5700/5707/5690/5717/6500/143471/5706/5705/10197/7316/10213/5709/4792/9861/5715/5701/5688/5687/23291/5685/5683/5708/5692/5686/5710/5702/5704/6233/7311/5694/5693/7314 39 Reovirus R-HSA-4641258 Degradation of DVL 35/2430 57/10654 4.291779296095759e-10 2.9708897096289814e-9 1.610441317542341e-9 5718/5689/5684/5682/5700/5707/5690/5717/143471/5706/5705/10197/8452/7316/10213/5709/9978/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/5704/6233/7311/5694/5693/7314 35 Reovirus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 45/2430 83/10654 4.820811063839196e-10 3.3198987532418384e-9 1.7996299576350333e-9 8454/5718/5689/8945/5684/4773/5966/5682/4772/5700/5707/5690/5717/6500/143471/5706/5705/10197/7316/10213/5709/4792/9861/5715/5701/5688/5687/23291/5685/5683/5708/5692/5686/5710/5702/5478/5704/6233/7311/3845/5694/3265/801/5693/7314 45 Reovirus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 63/2430 134/10654 4.978650162902277e-10 3.411013650070483e-9 1.8490209511885378e-9 5295/8454/5718/5689/3725/8945/5684/6464/4773/5290/5682/4772/5700/7321/5707/3937/5690/5594/5717/6500/143471/5706/5705/10197/7316/10213/5709/7335/4792/6850/10768/9861/7322/5715/5701/5688/5687/23291/5685/5683/5708/5692/5686/5710/5702/7189/5704/6233/2885/7410/7409/7311/5296/3845/5599/7334/5694/3265/801/5693/997/7314/5879 63 Reovirus R-HSA-73894 DNA Repair 125/2430 334/10654 6.694132072587942e-10 4.562939004580352e-9 2.473449444651183e-9 10450/8467/51750/1017/7014/6118/25913/3838/6917/5434/5440/5893/221120/151987/5888/100534599/2074/5883/322/328/27339/7486/5430/10111/83444/56852/5436/7320/7520/7515/7013/5531/51548/9636/11200/545/472/6613/5441/7706/7336/86/5438/580/5431/11073/5591/8450/5435/54778/7316/9978/5433/9031/8314/26277/641/5111/5426/9100/1643/10459/7415/7517/10980/9656/6119/83932/22976/7341/5437/1161/1642/5429/54617/5985/25898/2033/165918/142/2068/5439/1111/10987/7157/8900/5984/1069/7329/4255/9246/8924/6233/672/7311/6047/7318/79184/56949/23030/55247/60/5536/8533/7156/8607/9716/6117/2175/5599/7334/10973/5981/7874/2547/57461/5424/1022/5432/91603/55183/7314/51514/8451/56655 125 Reovirus R-HSA-5654738 Signaling by FGFR2 41/2430 73/10654 6.77428245670843e-10 4.594132671148458e-9 2.4903587123779858e-9 5295/2963/5434/5440/6464/5290/23543/5430/5436/5594/3178/5441/5438/5431/5435/4686/7316/5433/3185/6714/2962/867/5437/4670/5439/6233/2885/3187/7073/7311/5518/2253/3845/3265/5781/5432/22916/5725/7314/5515/5516 41 Reovirus R-HSA-73893 DNA Damage Bypass 31/2430 48/10654 6.996436718697816e-10 4.72082800817186e-9 2.559036928476394e-9 6118/56852/7320/9636/7706/8450/7316/9978/5111/5426/9100/10459/7415/6119/83932/1642/5429/5985/25898/5984/9246/6233/7311/7318/6117/5981/5424/7314/51514/8451/56655 31 Reovirus R-HSA-68867 Assembly of the pre-replicative complex 39/2430 68/10654 7.646093680414953e-10 5.133256862831345e-9 2.782603783192535e-9 5718/5689/5684/5000/5682/5700/5707/5690/5717/4173/143471/5706/5705/10197/7316/10213/5709/4174/84515/4171/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/5704/6233/7311/5694/5693/4176/7314 39 Reovirus R-HSA-191859 snRNP Assembly 33/2430 53/10654 8.063998773403765e-10 5.359951423516134e-9 2.9054889531823985e-9 23165/4928/6635/81929/5903/6633/6632/11218/7175/6606/9631/6637/348995/79023/57122/4686/23279/9688/79902/23225/79084/8086/6636/6634/10419/8021/6396/129401/55746/22916/8480/6628/79760 33 Reovirus R-HSA-194441 Metabolism of non-coding RNA 33/2430 53/10654 8.063998773403765e-10 5.359951423516134e-9 2.9054889531823985e-9 23165/4928/6635/81929/5903/6633/6632/11218/7175/6606/9631/6637/348995/79023/57122/4686/23279/9688/79902/23225/79084/8086/6636/6634/10419/8021/6396/129401/55746/22916/8480/6628/79760 33 Reovirus R-HSA-8939211 ESR-mediated signaling 91/2430 223/10654 1.020282774400789e-9 6.748008844551753e-9 3.6579184407907394e-9 5295/2788/27161/3725/2963/3838/5434/5440/5590/6464/5290/54331/6801/59345/5430/207/5436/57690/5594/3315/10681/27327/10274/51764/94235/5441/10735/5481/192670/200845/5438/5431/5885/2100/5435/5433/55970/5469/1105/1655/6667/2792/2289/6714/2099/4609/2962/1387/5437/2793/3320/2033/8243/2785/9126/595/2783/2784/2782/5439/192669/3065/861/23028/2786/23112/2771/10498/3326/7514/1025/23030/1386/1956/5536/3169/5296/4343/3845/3276/3265/26523/801/8877/5432/3480/2791/2288/10728/2790/2787 91 Reovirus R-HSA-162599 Late Phase of HIV Life Cycle 64/2430 139/10654 1.064344174360679e-9 7.00474786672841e-9 3.797089924605378e-9 6884/23165/5905/4928/2963/6917/81929/5434/5440/5903/7175/9631/5430/6874/5436/6749/348995/10015/79023/57122/5441/5438/5431/5435/79720/4686/7316/5433/4836/23279/9688/8148/79902/9525/2962/23327/5437/23225/2068/5439/5901/8086/5478/6233/7514/1025/7311/6881/6880/8021/7251/11198/6396/129401/6829/1104/51497/1022/5432/55746/22916/8480/7314/25920 64 Reovirus R-HSA-2871837 FCERI mediated NF-kB activation 44/2430 82/10654 1.1660981461909567e-9 7.636799624074109e-9 4.139708589160878e-9 8454/5718/5689/8945/5684/5682/5700/7321/5707/5690/5717/6500/143471/5706/5705/10197/7316/10213/5709/7335/4792/9861/7322/5715/5701/5688/5687/23291/5685/5683/5708/5692/5686/5710/5702/7189/5704/6233/7311/7334/5694/5693/997/7314 44 Reovirus R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 34/2430 56/10654 1.172732642883915e-9 7.642784443380051e-9 4.142952802588619e-9 5718/5689/5684/5682/5700/5707/5690/5717/143471/5706/5705/10197/7316/10213/5709/7415/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/5704/6233/7311/5694/5693/7314 34 Reovirus R-HSA-392851 Prostacyclin signalling through prostacyclin receptor 17/2430 19/10654 1.237183334702042e-9 8.023674442533632e-9 4.349423271716939e-9 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Reovirus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 25/2430 35/10654 1.2910960528027969e-9 8.33287114272723e-9 4.517030685625854e-9 23165/4928/81929/5903/7175/9631/7884/348995/79023/57122/4686/23279/9688/79902/23225/10189/10482/8086/1977/8021/6396/129401/55746/22916/8480 25 Reovirus R-HSA-5358351 Signaling by Hedgehog 67/2430 149/10654 1.4979530664941387e-9 9.621467773250814e-9 5.215545089817649e-9 8454/57154/5718/5689/8945/84617/5684/5682/54903/5700/5707/1452/5690/10382/5717/6500/409/79577/7277/143471/5706/10381/5705/10197/7278/64750/5573/8452/7316/10213/5709/9978/7415/9861/5566/5715/2932/5701/5688/5687/7846/113457/5685/5683/347733/5708/5692/5686/408/10376/5710/5702/81027/83737/5577/5704/6233/7311/10383/23322/84790/5694/8481/5693/7280/5034/7314 67 Reovirus R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 35/2430 59/10654 1.6251220582023063e-9 1.038834004669034e-8 5.631246416737278e-9 5718/5689/5684/5000/5682/5700/5707/5690/5717/143471/5706/5705/10197/7316/10213/5709/84515/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/5704/6233/7311/5694/5693/7314 35 Reovirus R-HSA-437239 Recycling pathway of L1 30/2430 47/10654 2.0085769348277117e-9 1.2760594136287221e-8 6.917183080496066e-9 1173/84617/161/79861/71/7430/51807/10382/5594/347688/7277/10381/7278/112714/6714/7846/113457/347733/1808/10376/6195/81027/163/6196/1213/10383/60/84790/6197/7280 30 Reovirus R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 19/2430 23/10654 2.024884698273122e-9 1.2760594136287221e-8 6.917183080496066e-9 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/5439/6829/51497/5432/22916/25920 19 Reovirus R-HSA-428930 Thromboxane signalling through TP receptor 19/2430 23/10654 2.024884698273122e-9 1.2760594136287221e-8 6.917183080496066e-9 2788/54331/59345/10681/6915/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787/10672 19 Reovirus R-HSA-168276 NS1 Mediated Effects on Host Pathways 27/2430 40/10654 2.0624085524098816e-9 1.2936046131547427e-8 7.0122910010279145e-9 23165/4928/3837/3838/81929/5903/7175/9631/8106/348995/9636/79023/57122/23279/9688/79902/10898/3840/23225/8086/3836/5610/8021/6396/129401/55746/8480 27 Reovirus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 54/2430 112/10654 2.770400927219389e-9 1.7295587097033195e-8 9.375483708445349e-9 5295/8454/5718/5689/8945/5684/4773/5966/5682/4690/4772/5700/5707/640/5690/5717/6500/143471/5706/5705/10197/7316/10213/5709/4792/6850/10768/9861/5715/5701/5688/5687/23291/5685/5683/5708/5692/5686/5710/5702/5478/974/30011/5704/6233/2885/7409/7311/3845/5694/3265/801/5693/7314 54 Reovirus R-HSA-202424 Downstream TCR signaling 49/2430 98/10654 3.21761110687578e-9 1.9994085761795543e-8 1.0838268991581575e-8 5295/8454/5718/5689/8945/5684/5290/5682/5700/7321/5707/5690/5717/6500/143471/5706/5705/10197/7316/10213/5709/920/7335/4792/9861/7322/5715/5701/5688/5687/23291/5685/5683/5708/5692/5686/5728/5710/5702/7189/5704/6233/7311/5296/7334/5694/5693/997/7314 49 Reovirus R-HSA-176033 Interactions of Vpr with host cellular proteins 25/2430 36/10654 3.309422818041589e-9 2.0375063985730707e-8 1.1044787285047846e-8 23165/4928/81929/5903/7175/9631/3159/348995/79023/57122/293/292/23279/9688/79902/11168/23225/8086/3836/8021/6396/129401/55746/8480/291 25 Reovirus R-HSA-177243 Interactions of Rev with host cellular proteins 25/2430 36/10654 3.309422818041589e-9 2.0375063985730707e-8 1.1044787285047846e-8 23165/5905/4928/3837/81929/5903/7175/9631/4869/348995/79023/57122/23279/9688/79902/23225/5901/8086/7514/8021/6396/129401/1104/55746/8480 25 Reovirus R-HSA-5658442 Regulation of RAS by GAPs 38/2430 68/10654 3.4605464526488467e-9 2.12077525721966e-8 1.1496165907399356e-8 5718/5689/5684/5682/5700/5707/5690/5717/143471/5706/5705/10197/8452/7316/10213/5709/9978/84078/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/5704/6233/7311/3845/5694/3265/5693/7314 38 Reovirus R-HSA-8852135 Protein ubiquitination 42/2430 79/10654 4.021414000214375e-9 2.4532461663408244e-8 1.3298403422963181e-8 11065/7319/7321/56852/65264/7320/10477/92912/79577/7336/7326/5591/7323/8239/7316/7317/54926/55236/51255/5111/7415/3093/7322/7347/8078/118424/7328/7324/6233/7327/23168/7311/55284/27338/7334/5195/7874/7332/3105/997/7314/123169 42 Reovirus R-HSA-159227 Transport of the SLBP independent Mature mRNA 24/2430 34/10654 4.090748482689719e-9 2.4841999876697564e-8 1.3466195962155628e-8 23165/4928/81929/5903/7175/9631/348995/79023/57122/4686/23279/9688/79902/23225/10189/10482/8086/1977/8021/6396/129401/55746/22916/8480 24 Reovirus R-HSA-4551638 SUMOylation of chromatin organization proteins 39/2430 71/10654 4.200747763734838e-9 2.5394565666740923e-8 1.3765727370562366e-8 1912/23165/23468/4928/81929/5903/7175/83746/9631/8535/6045/80012/348995/79023/6613/57122/9759/1911/23279/9688/79902/7341/84733/23225/23512/57332/3066/3065/1107/8086/7329/8021/6396/648/129401/7703/55746/8480/6015 39 Reovirus R-HSA-157118 Signaling by NOTCH 93/2430 235/10654 4.346894875318849e-9 2.615969168209902e-8 1.4180482096820142e-8 8454/5718/4192/5689/27161/3725/5684/8841/79885/142678/5682/5584/2648/9734/7027/5700/5707/23462/207/4904/5690/57690/5717/6500/27327/409/3091/51548/10013/23385/5706/3955/5705/10197/192670/7534/488/7316/10213/5709/9978/4854/9611/9759/1024/4609/5664/11060/9861/10014/5715/5870/22938/5701/5688/1387/5687/4088/5685/5683/5708/59/5692/5686/2033/408/595/55294/5710/3002/5702/192669/3066/3065/7157/83737/861/2683/23112/5704/83464/6233/7311/1956/4343/55851/51107/5694/26523/4851/5693/5663/7314 93 Reovirus R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 23/2430 32/10654 4.95215982539112e-9 2.9668544962881332e-8 1.6082539343257446e-8 2788/54331/59345/5594/10681/409/51764/94235/55970/2792/6714/2793/408/2785/2783/2784/2782/2786/2791/2147/2790/2787/10672 23 Reovirus R-HSA-418217 G beta:gamma signalling through PLC beta 17/2430 20/10654 6.483516253075181e-9 3.8669543366555544e-8 2.096174427685961e-8 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Reovirus R-HSA-392170 ADP signalling through P2Y purinoceptor 12 18/2430 22/10654 7.396844442952374e-9 4.3920818559041654e-8 2.380832269825138e-8 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2771/2791/2790/2787 18 Reovirus R-HSA-203927 MicroRNA (miRNA) biogenesis 19/2430 24/10654 7.63140974381592e-9 4.5113112467867566e-8 2.445463392522288e-8 27161/5434/5440/5430/5436/5441/192670/5438/5431/5435/54487/5433/5437/5439/192669/5901/29102/26523/5432 19 Reovirus R-HSA-5387390 Hh mutants abrogate ligand secretion 34/2430 59/10654 7.919379262944775e-9 4.660921011142828e-8 2.5265629181108297e-8 5718/5689/5684/5682/5700/5707/5690/5717/143471/5706/5705/10197/7316/10213/5709/7415/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/5704/6233/7311/5694/5693/7314 34 Reovirus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 46/2430 92/10654 9.715923495423656e-9 5.6931902587219314e-8 3.086128977309083e-8 6884/1017/6118/5883/1459/7486/10111/6874/8445/22974/9212/1460/6749/11200/545/472/580/11073/7316/1457/6790/641/8148/6119/1432/6794/5985/1111/7157/8900/5984/6233/672/7311/6881/5562/6880/5300/7156/6117/11198/5600/1020/26155/7314/4193 46 Reovirus R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 24/2430 35/10654 1.0199081056988374e-8 5.924335779189769e-8 3.211426895747369e-8 23165/4928/81929/5903/7175/9631/91754/10783/348995/79023/9133/57122/891/983/23279/9688/79902/23225/8086/8021/6396/129401/55746/8480 24 Reovirus R-HSA-8953750 Transcriptional Regulation by E2F6 24/2430 35/10654 1.0199081056988374e-8 5.924335779189769e-8 3.211426895747369e-8 23468/5888/83746/7027/2146/8317/6045/84108/80012/5931/4149/11335/1876/1911/5928/10138/23512/1111/672/8726/648/7703/10919/6015 24 Reovirus R-HSA-2980766 Nuclear Envelope Breakdown 31/2430 52/10654 1.1844048667667843e-8 6.850064510824345e-8 3.713240138234438e-8 4000/23165/4928/81929/5903/7175/9631/91754/10783/348995/79023/9133/57122/7443/891/983/23279/9688/79902/23225/7444/8086/2010/4001/5347/8021/6396/129401/55746/7112/8480 31 Reovirus R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 23/2430 33/10654 1.2810113708252088e-8 7.345198246448408e-8 3.98163913769028e-8 23165/3303/4928/81929/5903/7175/9631/348995/79023/57122/23279/9688/79902/23225/5901/8086/7514/8021/6396/129401/3304/55746/8480 23 Reovirus R-HSA-180746 Nuclear import of Rev protein 23/2430 33/10654 1.2810113708252088e-8 7.345198246448408e-8 3.98163913769028e-8 23165/4928/3837/81929/5903/7175/9631/4869/348995/79023/57122/23279/9688/79902/23225/5901/8086/8021/6396/129401/1104/55746/8480 23 Reovirus R-HSA-202403 TCR signaling 55/2430 119/10654 1.3308297217224585e-8 7.598241488124805e-8 4.1188072359201594e-8 5295/8454/5718/5689/8945/5684/5290/5682/4690/5700/7321/5707/3937/5690/5717/6500/143471/5706/5705/10197/7316/10213/5709/920/7335/4792/9861/7322/5715/5701/5688/5687/23291/5685/5683/55824/5708/5692/5686/7408/5728/1445/5710/5702/7189/7535/5704/6233/7311/5296/7334/5694/5693/997/7314 55 Reovirus R-HSA-2132295 MHC class II antigen presentation 56/2430 123/10654 1.913972592170284e-8 1.0881137800593614e-7 5.898379141828243e-8 1173/84617/161/79861/11258/1783/51807/10484/10120/10382/347688/29127/3798/821/55860/830/7277/10381/7278/112714/1780/1781/8655/1639/832/10121/3796/10112/1062/972/7846/5476/113457/89953/347733/10376/51143/10540/81027/11004/163/3799/1213/10383/84790/84643/6396/375/22920/81930/7879/140735/1075/7280/829/1778 56 Reovirus R-HSA-70326 Glucose metabolism 45/2430 91/10654 2.1697785217605356e-8 1.2283152987593542e-7 6.658374767935988e-8 5105/23165/4928/7167/81929/5903/2597/7175/9631/5091/5315/2806/1468/8402/5211/348995/79023/57122/5214/6576/5528/5230/10165/23279/9688/79902/5566/26330/5519/2023/23225/2821/8604/8086/5213/5518/4191/8021/6396/129401/55746/10007/8480/5515/5516 45 Reovirus R-HSA-9009391 Extra-nuclear estrogen signaling 40/2430 77/10654 2.2371150396023293e-8 1.2610910096661232e-7 6.836043292233632e-8 5295/2788/5590/6464/5290/54331/6801/59345/207/5594/3315/10681/51764/94235/2100/55970/2792/6714/2099/2793/3320/2785/595/2783/2784/2782/2786/2771/7514/1956/5296/3845/3276/3265/801/8877/3480/2791/2790/2787 40 Reovirus R-HSA-8851708 Signaling by FGFR2 IIIa TM 16/2430 19/10654 2.435017032181807e-8 1.3668835105020562e-7 7.409516665816379e-8 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/5439/5432/22916 16 Reovirus R-HSA-392451 G beta:gamma signalling through PI3Kgamma 19/2430 25/10654 2.4971025679588702e-8 1.3900537628304377e-7 7.535116520858345e-8 2788/54331/59345/207/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/387/2791/2790/2787 19 Reovirus R-HSA-418592 ADP signalling through P2Y purinoceptor 1 19/2430 25/10654 2.4971025679588702e-8 1.3900537628304377e-7 7.535116520858345e-8 2788/54331/59345/10681/51764/94235/55970/2792/6714/1432/2793/2785/2783/2784/2782/2786/2791/2790/2787 19 Reovirus R-HSA-8943724 Regulation of PTEN gene transcription 34/2430 61/10654 2.52422581081592e-8 1.3993218602697382e-7 7.585356443945633e-8 1912/3725/8841/5468/2146/5978/8535/6045/5594/80012/5931/1911/1108/2122/64223/10014/5928/84733/23512/57332/6615/3066/3065/7157/1107/23028/2475/55004/1386/8726/648/23466/57521/6015 34 Reovirus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 18/2430 23/10654 2.6735899523797693e-8 1.4653761308855614e-7 7.943419303886433e-8 7321/6497/64750/7323/8239/54778/7316/9611/23327/4088/142/5494/3065/6498/4087/6233/7311/7314 18 Reovirus R-HSA-5620922 BBSome-mediated cargo-targeting to cilium 18/2430 23/10654 2.6735899523797693e-8 1.4653761308855614e-7 7.943419303886433e-8 10694/582/79738/10575/123016/585/7203/10576/6950/55212/117177/583/22948/92482/8195/129880/166379/27241 18 Reovirus R-HSA-500657 Presynaptic function of Kainate receptors 17/2430 21/10654 2.676285748024528e-8 1.4653761308855614e-7 7.943419303886433e-8 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Reovirus R-HSA-1236974 ER-Phagosome pathway 42/2430 83/10654 2.7164480373627476e-8 1.4812957460884205e-7 8.029715358563137e-8 5718/5689/5684/10952/5682/5700/3107/5707/5690/55176/5717/811/143471/5706/5705/10197/9554/23480/7316/10213/5709/29927/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/2923/5710/5702/5704/6233/7311/5694/3105/5693/7314 42 Reovirus R-HSA-4608870 Asymmetric localization of PCP proteins 35/2430 64/10654 3.0457572303504005e-8 1.6541185608732256e-007 8.966542466756848e-8 57154/5718/5689/5684/5682/5700/5707/5690/5717/143471/5706/5705/10197/64750/7316/10213/5709/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/5704/6233/7311/5694/5693/7314 35 Reovirus R-HSA-165054 Rev-mediated nuclear export of HIV RNA 23/2430 34/10654 3.1041513725337085e-8 1.6790065723502164e-7 9.10145384318428e-8 23165/5905/4928/81929/5903/7175/9631/348995/79023/57122/23279/9688/79902/23225/5901/8086/7514/8021/6396/129401/1104/55746/8480 23 Reovirus R-HSA-392518 Signal amplification 22/2430 32/10654 3.961461254289496e-8 2.134077514407567e-7 1.1568273951405656e-7 2788/54331/59345/10681/6915/51764/94235/55970/2792/6714/1432/2793/2785/2783/2784/2782/2786/2771/2791/2790/2787/10672 22 Reovirus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 29/2430 49/10654 4.41557809352406e-8 2.3691615794972467e-7 1.2842602952206946e-7 1017/9134/7027/4849/4869/898/4850/2810/9337/891/983/1026/6790/5111/25904/246175/4848/23019/2033/7157/8900/10498/55571/55835/581/57472/3276/85456/29883 29 Reovirus R-HSA-190236 Signaling by FGFR 43/2430 87/10654 4.533744516661455e-8 2.4228330697038815e-7 1.3133542010370867e-7 5295/2963/5434/5440/6464/5290/23543/5430/5436/5594/3178/5441/2260/5438/5431/5435/4686/7316/5433/3185/6714/2962/2261/867/5437/4670/5439/6233/2885/3187/7073/7311/5518/2253/3845/3265/5781/5432/22916/5725/7314/5515/5516 43 Reovirus R-HSA-3371568 Attenuation phase 13/2430 14/10654 4.871742728888129e-8 2.5930869664520076e-7 1.4056443688299567e-7 3303/3337/3305/1387/3320/2033/3326/3306/3304/3312/3297/2288/10728 13 Reovirus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 21/2430 30/10654 4.968269184111579e-8 2.633971281735345e-7 1.4278066828190334e-7 6118/56852/7320/8450/7316/9978/5111/5426/6119/1642/5985/5984/6233/7311/6117/5981/5424/7314/51514/8451/56655 21 Reovirus R-HSA-6784531 tRNA processing in the nucleus 32/2430 57/10654 5.15182879513498e-8 2.713923036675809e-7 1.4711464302182135e-7 23165/4928/81929/5903/54913/7175/9631/10557/29894/348995/79023/57122/10978/1478/23279/9688/79902/11102/10898/23225/5901/8086/10556/1653/8021/10799/6396/129401/55746/51493/8480/79897 32 Reovirus R-HSA-5358346 Hedgehog ligand biogenesis 35/2430 65/10654 5.159703976913589e-8 2.713923036675809e-7 1.4711464302182135e-7 5718/5689/5684/5682/5700/5707/5690/5717/143471/5706/5705/10197/7316/10213/5709/7415/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/5704/6233/7311/5694/5693/5034/7314 35 Reovirus R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic 47/2430 99/10654 5.369271141834229e-8 2.813076959015894e-7 1.524895168454881e-7 22820/84617/79861/51807/10382/347688/29127/3798/5861/7277/10381/55605/7278/112714/9554/1315/23303/3796/9183/10112/11316/1062/6836/7846/113457/89953/547/347733/8729/10376/10972/1314/81027/381/11004/9276/3833/3799/10383/84790/84643/378/375/22920/81930/7280/54732 47 Reovirus R-HSA-5689603 UCH proteinases 48/2430 102/10654 5.4924827152035755e-8 2.866389416996866e-7 1.553794452327327e-7 5718/5689/5684/5682/5700/5707/83444/171023/4738/5690/5717/143471/5706/5705/10197/86/580/7316/10213/5709/8314/55252/9861/5715/5701/5688/5687/7347/5685/5683/5708/54617/5692/5686/5710/8473/5702/9958/5704/6233/7311/60/7040/8607/7345/5694/5693/7314 48 Reovirus R-HSA-5683057 MAPK family signaling cascades 107/2430 294/10654 6.378664334170981e-8 3.315912665545693e-7 1.7974692041407476e-7 5718/5689/27161/3725/5684/6464/1437/3667/71/5682/2065/5525/5700/10642/5707/5526/8844/10048/7094/84292/5690/57690/5594/2322/5717/3315/27327/409/7414/143471/5706/2064/5705/10197/3337/192670/2260/8452/5528/4684/7316/10213/5709/9978/3560/983/5597/84078/3718/6714/4609/9861/5566/5715/5519/2261/5701/5688/5687/5685/5683/5708/5692/5686/2335/408/80824/5529/1445/5710/5702/192669/998/5894/8556/23112/5704/6233/5527/2885/6709/7514/7311/8826/5518/1956/60/5536/4140/4343/2253/3845/5694/3265/26523/369/801/7297/5781/5693/5245/7529/7314/5879/11221/5515/5516 107 Reovirus R-HSA-5621481 C-type lectin receptors (CLRs) 61/2430 142/10654 6.464665387438835e-8 3.3475941696194897e-7 1.8146429157723044e-7 8454/5718/5689/8945/5684/4773/5682/4772/5700/7321/5707/5690/9039/5717/6500/29108/143471/5706/5705/841/10197/7316/10213/5709/7335/4792/6850/10768/6714/9861/5566/7322/5715/5701/5688/1387/5687/23291/5685/5683/5708/5692/5686/2033/5710/5702/9040/5894/7189/5704/6233/5580/7311/3845/7334/5694/3265/801/5693/997/7314 61 Reovirus R-HSA-5632684 Hedgehog 'on' state 42/2430 85/10654 6.554382607260716e-8 3.380947939498192e-7 1.8327231187951115e-7 57154/5718/5689/5684/5682/5700/5707/1452/5690/5717/409/79577/143471/5706/5705/10197/64750/8452/7316/10213/5709/9978/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/408/5710/5702/83737/5704/6233/7311/5694/5693/7314 42 Reovirus R-HSA-205043 NRIF signals cell death from the nucleus 14/2430 16/10654 7.467382700904097e-8 3.8370858801568747e-7 2.079983521547376e-7 8878/23421/23385/7316/5664/7189/83464/6233/7311/5599/55851/51107/5663/7314 14 Reovirus R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 29/2430 50/10654 8.229571797984462e-8 4.2125317709223143e-7 2.2835028824413426e-7 5718/5689/5684/5682/5700/5707/5690/5717/143471/5706/5705/10197/10213/5709/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/5704/5694/5693 29 Reovirus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 32/2430 58/10654 8.990841867867147e-8 4.515701028372372e-7 2.447842977875978e-7 8454/8841/79885/142678/2648/9734/23462/6500/10013/23385/7316/9978/9611/9759/1024/4609/5664/10014/22938/1387/2033/55294/3066/3065/83464/6233/7311/55851/51107/4851/5663/7314 32 Reovirus R-HSA-2644603 Signaling by NOTCH1 in Cancer 32/2430 58/10654 8.990841867867147e-8 4.515701028372372e-7 2.447842977875978e-7 8454/8841/79885/142678/2648/9734/23462/6500/10013/23385/7316/9978/9611/9759/1024/4609/5664/10014/22938/1387/2033/55294/3066/3065/83464/6233/7311/55851/51107/4851/5663/7314 32 Reovirus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 32/2430 58/10654 8.990841867867147e-8 4.515701028372372e-7 2.447842977875978e-7 8454/8841/79885/142678/2648/9734/23462/6500/10013/23385/7316/9978/9611/9759/1024/4609/5664/10014/22938/1387/2033/55294/3066/3065/83464/6233/7311/55851/51107/4851/5663/7314 32 Reovirus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 32/2430 58/10654 8.990841867867147e-8 4.515701028372372e-7 2.447842977875978e-7 8454/8841/79885/142678/2648/9734/23462/6500/10013/23385/7316/9978/9611/9759/1024/4609/5664/10014/22938/1387/2033/55294/3066/3065/83464/6233/7311/55851/51107/4851/5663/7314 32 Reovirus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 32/2430 58/10654 8.990841867867147e-8 4.515701028372372e-7 2.447842977875978e-7 8454/8841/79885/142678/2648/9734/23462/6500/10013/23385/7316/9978/9611/9759/1024/4609/5664/10014/22938/1387/2033/55294/3066/3065/83464/6233/7311/55851/51107/4851/5663/7314 32 Reovirus R-HSA-180910 Vpr-mediated nuclear import of PICs 22/2430 33/10654 9.322361021218043e-8 4.664672031590751e-7 2.5285962478210185e-7 23165/4928/81929/5903/7175/9631/3159/348995/79023/57122/23279/9688/79902/11168/23225/8086/3836/8021/6396/129401/55746/8480 22 Reovirus R-HSA-2559583 Cellular Senescence 77/2430 195/10654 1.0335311244253781e-7 5.1522297844489e-7 2.792888505909898e-7 1912/1017/7014/3725/25913/9134/1019/11065/5606/3159/246184/1029/7027/7321/2146/10111/8535/6045/8697/57690/5594/27327/80012/898/5931/5925/7013/472/192670/8881/7316/6774/1026/9261/1911/26277/6667/51433/5598/5928/1432/84733/23512/119504/57332/6195/192669/7157/8900/51529/23135/7324/4001/64682/29945/10393/23112/6233/51434/51343/6196/7311/25906/4343/8726/6197/29882/5599/648/5600/23466/26523/10919/7314/996/6015/4193 77 Reovirus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 37/2430 72/10654 1.0838548569856696e-7 5.369941445147725e-7 2.9109042816432673e-7 84617/10890/79861/71/7531/51807/7532/207/10971/10382/347688/2810/7277/10381/7278/7534/112714/5872/8766/4641/5898/7846/113457/347733/10376/81027/51552/6844/10383/60/84790/801/22920/4218/7280/7529/5879 37 Reovirus R-HSA-4086400 PCP/CE pathway 44/2430 92/10654 1.0852426573277589e-7 5.369941445147725e-7 2.9109042816432673e-7 57154/5718/5689/1173/5684/161/5682/5700/5707/5690/5717/409/143471/5706/5705/10197/64750/7316/10213/5709/5216/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/23002/5710/5702/5704/6233/163/7311/1213/387/5694/5693/7314/5879 44 Reovirus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 24/2430 38/10654 1.1380996613968298e-7 5.610705341793966e-7 3.041416069298966e-7 23165/4928/81929/5903/7175/9631/348995/79023/57122/23279/9688/79902/7341/23225/7428/8086/7329/5371/8021/6396/129401/55746/8480/4193 24 Reovirus R-HSA-6807878 COPI-mediated anterograde transport 47/2430 101/10654 1.1555885576433063e-7 5.675979091953887e-7 3.0767992556447166e-7 22820/84617/79861/11258/1783/51807/10382/347688/5861/55860/830/7277/10381/7278/112714/1780/1781/8655/1315/1639/832/10282/10121/2804/11316/7846/113457/347733/8729/10376/10972/51143/1314/10540/81027/381/9276/6709/10383/84790/378/375/140735/7280/54732/829/1778 47 Reovirus R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 21/2430 31/10654 1.2086957447827598e-7 5.893494580400609e-7 3.194708691550283e-7 23165/4928/3837/81929/5903/7175/9631/348995/79023/57122/23279/9688/79902/23225/8086/3836/8021/6396/129401/55746/8480 21 Reovirus R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 21/2430 31/10654 1.2086957447827598e-7 5.893494580400609e-7 3.194708691550283e-7 23165/4928/81929/5903/7175/9631/348995/79023/57122/23279/9688/79902/23225/5901/8086/7514/8021/6396/129401/55746/8480 21 Reovirus R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 29/2430 51/10654 1.4935058226280882e-7 7.255722832840459e-7 3.93313686494976e-7 5718/5689/5684/5682/5700/5707/5690/5717/143471/5706/5705/10197/10213/5709/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/5704/5694/5693 29 Reovirus R-HSA-983189 Kinesins 32/2430 59/10654 1.5371269464147247e-7 7.388081941563359e-7 4.0048852629968413e-7 84617/79861/51807/10382/347688/29127/3798/7277/10381/55605/7278/112714/23303/3796/10112/1062/7846/113457/89953/547/347733/10376/81027/11004/3833/3799/10383/84790/84643/22920/81930/7280 32 Reovirus R-HSA-6804757 Regulation of TP53 Degradation 23/2430 36/10654 1.5416301576353236e-7 7.388081941563359e-7 4.0048852629968413e-7 1017/1029/207/11200/472/7316/80196/983/64223/5519/7157/8900/6233/5527/2475/7311/5518/7874/7314/253260/4193/5515/5516 23 Reovirus R-HSA-5205647 Mitophagy 20/2430 29/10654 1.5428704054612105e-7 7.388081941563359e-7 4.0048852629968413e-7 65018/1459/8878/10452/1460/7416/100188893/192111/7316/1457/6714/56993/81631/6233/9804/7311/84557/54543/401505/7314 20 Reovirus R-HSA-9619483 Activation of AMPK downstream of NMDARs 20/2430 29/10654 1.5428704054612105e-7 7.388081941563359e-7 4.0048852629968413e-7 84617/79861/51807/10382/347688/7277/10381/7278/112714/7846/113457/347733/10376/4137/81027/5562/10383/84790/801/7280 20 Reovirus R-HSA-170834 Signaling by TGF-beta Receptor Complex 37/2430 73/10654 1.718230788024422e-7 8.198415474287956e-7 4.444145797597001e-7 57154/5590/7027/7321/6497/10273/4738/64750/7323/8239/54778/7316/9611/5501/1024/6667/4609/22938/23327/867/4088/142/5494/3065/6498/9958/9040/4087/5499/6233/7514/1025/7311/387/7040/57530/7314 37 Reovirus R-HSA-8848021 Signaling by PTK6 30/2430 54/10654 1.8462768027040066e-7 8.746900029831748e-7 4.741464875925183e-7 120892/1017/1019/5770/2065/207/9021/27043/898/202559/3091/2064/10657/7316/5753/6774/867/6421/2908/595/6233/1398/7311/387/1956/3845/3265/5829/7314/5879 30 Reovirus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 30/2430 54/10654 1.8462768027040066e-7 8.746900029831748e-7 4.741464875925183e-7 120892/1017/1019/5770/2065/207/9021/27043/898/202559/3091/2064/10657/7316/5753/6774/867/6421/2908/595/6233/1398/7311/387/1956/3845/3265/5829/7314/5879 30 Reovirus R-HSA-4085377 SUMOylation of SUMOylation proteins 22/2430 34/10654 2.0722412043806243e-7 9.782735862376373e-7 5.302964287200555e-7 23165/4928/81929/5903/7175/9631/348995/79023/6613/57122/23279/9688/79902/7341/23225/8086/7329/8021/6396/129401/55746/8480 22 Reovirus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 24/2430 39/10654 2.3198767095690198e-7 1.0913222830930318e-6 5.915771594453245e-7 6118/9636/7706/7316/5111/5426/9100/10459/7415/6119/83932/5429/5985/25898/5984/9246/6233/7311/7318/6117/5981/5424/7314/56655 24 Reovirus R-HSA-9020702 Interleukin-1 signaling 47/2430 103/10654 2.4043644827050593e-7 1.1270985785592841e-6 6.109705499911655e-7 8454/5718/5689/8945/5684/351/5682/5700/5707/5690/8878/54472/5717/6500/143471/5706/5705/10197/7316/10213/5709/9978/79155/7335/4792/9861/5715/5701/5688/5687/23291/5685/5683/5708/5692/5686/5710/5702/3654/7189/5704/6233/7311/7334/5694/5693/7314 47 Reovirus R-HSA-70171 Glycolysis 36/2430 71/10654 2.4858945608812347e-7 1.161243053614451e-6 6.29479373531943e-7 23165/4928/7167/81929/5903/2597/7175/9631/5315/5211/348995/79023/57122/5214/5528/5230/23279/9688/79902/5566/26330/5519/2023/23225/2821/8086/5213/5518/8021/6396/129401/55746/10007/8480/5515/5516 36 Reovirus R-HSA-913531 Interferon Signaling 77/2430 199/10654 2.7615997015988764e-7 1.2855390945421946e-6 6.968569942050347e-7 23165/3665/4928/3837/3838/81929/5903/6737/7175/960/5770/9631/4281/7412/3107/2316/9021/9830/23650/348995/9636/79023/3383/57122/8638/1982/7706/9470/4684/7316/2317/103/4734/3434/8651/23279/9688/3433/3659/79902/8672/3840/7341/6059/23225/1981/1973/10612/8086/7324/3836/9246/1977/5371/51191/4599/6233/5580/7311/7318/5610/5300/8021/9775/4940/6396/3437/129401/7334/7297/5781/55746/3105/5495/1974/8480/7314 77 Reovirus R-HSA-5619084 ABC transporter disorders 38/2430 77/10654 2.8662415442103974e-7 1.3106209172949205e-6 7.104531918522734e-7 5718/5689/5684/5682/5700/5707/6048/5690/5717/1080/143471/5706/5705/10197/7316/10213/5709/7415/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/10613/5704/6233/7311/11160/5694/5693/7314 38 Reovirus R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 13/2430 15/10654 2.8841508209933133e-7 1.3106209172949205e-6 7.104531918522734e-7 1499/5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 13 Reovirus R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 13/2430 15/10654 2.8841508209933133e-7 1.3106209172949205e-6 7.104531918522734e-7 1499/5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 13 Reovirus R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 13/2430 15/10654 2.8841508209933133e-7 1.3106209172949205e-6 7.104531918522734e-7 1499/5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 13 Reovirus R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 13/2430 15/10654 2.8841508209933133e-7 1.3106209172949205e-6 7.104531918522734e-7 1499/5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 13 Reovirus R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 13/2430 15/10654 2.8841508209933133e-7 1.3106209172949205e-6 7.104531918522734e-7 1499/5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 13 Reovirus R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 13/2430 15/10654 2.8841508209933133e-7 1.3106209172949205e-6 7.104531918522734e-7 1499/5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 13 Reovirus R-HSA-6806003 Regulation of TP53 Expression and Degradation 23/2430 37/10654 3.195543707828724e-7 1.4472021673420933e-6 7.844903018683897e-7 1017/1029/207/11200/472/7316/80196/983/64223/5519/7157/8900/6233/5527/2475/7311/5518/7874/7314/253260/4193/5515/5516 23 Reovirus R-HSA-110320 Translesion Synthesis by POLH 15/2430 19/10654 3.390696171476264e-7 1.530395299017665e-6 8.295871145005937e-7 6118/7316/5111/7415/6119/83932/5429/5985/25898/5984/6233/7311/6117/5981/7314 15 Reovirus R-HSA-390450 Folding of actin by CCT/TriC 10/2430 10/10654 3.755932023473735e-7 1.6895370987747173e-6 9.158537062377918e-7 10694/10575/7203/10576/908/6950/10574/60/22948/10693 10 Reovirus R-HSA-5675221 Negative regulation of MAPK pathway 24/2430 40/10654 4.547544536637868e-7 2.0387649332040913e-6 1.105160947088256e-6 5525/5526/8844/5594/5528/7316/5519/80824/5529/5894/6233/5527/7311/5518/5536/4140/3845/3265/369/7529/7314/11221/5515/5516 24 Reovirus R-HSA-113418 Formation of the Early Elongation Complex 21/2430 33/10654 5.958385621046939e-7 2.6534677299062366e-6 1.4383751955369452e-6 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/2068/5439/6829/51497/1022/5432/22916/25920 21 Reovirus R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 21/2430 33/10654 5.958385621046939e-7 2.6534677299062366e-6 1.4383751955369452e-6 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/2068/5439/6829/51497/1022/5432/22916/25920 21 Reovirus R-HSA-1980143 Signaling by NOTCH1 36/2430 73/10654 5.998997107022435e-7 2.6626777857082967e-6 1.4433677249978792e-6 8454/8841/79885/142678/2648/9734/23462/6500/409/3091/10013/23385/7316/9978/9611/9759/1024/4609/5664/10014/22938/1387/2033/408/55294/3066/3065/83737/83464/6233/7311/55851/51107/4851/5663/7314 36 Reovirus R-HSA-351202 Metabolism of polyamines 31/2430 59/10654 6.130888536654327e-7 2.7122076440298616e-6 1.4702165608986326e-6 5718/5689/5684/5682/5700/5707/5690/5717/54498/143471/5706/5705/10197/10213/5709/79814/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/5710/5702/5704/5694/5693 31 Reovirus R-HSA-195721 Signaling by WNT 114/2430 331/10654 6.603233647526346e-7 2.9115248030017155e-6 1.5782611601522064e-6 2788/8454/57154/5718/9070/5689/27161/8945/1173/5684/7476/161/54331/7015/1487/5682/1499/5525/59345/1459/4772/5700/5707/5526/207/1454/1452/5690/57690/5717/5929/6500/10681/27327/409/79577/51764/1460/94235/143471/5706/5705/10197/6657/192670/7534/64750/8452/5528/55366/7316/10213/5709/9978/55970/1457/5216/2792/6934/4609/9861/81847/5715/5519/2932/5701/5688/1387/2793/5687/5685/5683/5708/5692/5686/324/2033/2785/2783/23002/2784/5529/5710/2782/5702/192669/3065/2786/23112/5704/6233/5527/7514/163/7311/5518/1213/387/8607/4343/25776/3845/5694/26523/801/5693/2791/7314/5879/2790/123169/5515/2787/5516 114 Reovirus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 33/2430 65/10654 7.536833180322034e-7 3.312239845036262e-6 1.7954782645642516e-6 3725/2963/6917/5434/5440/8621/5430/5436/6749/545/472/5441/5438/5431/5435/5433/1643/2962/9656/5437/2068/5439/1111/7157/672/1025/1386/11198/6829/51497/1022/5432/25920 33 Reovirus R-HSA-3371511 HSF1 activation 11/2430 12/10654 8.112325834907267e-7 3.5534646935856094e-6 1.9262399221453666e-6 6118/7531/1915/10013/7415/6119/3320/3326/6117/3297/10728 11 Reovirus R-HSA-5688426 Deubiquitination 104/2430 297/10654 8.44697878079288e-7 3.6879619774964987e-6 1.9991473688288615e-6 5718/5689/5684/5682/2648/7419/5700/7321/5707/991/83444/8237/171023/4738/5690/55611/9817/5717/409/6478/1080/3091/143471/5706/5705/57695/4287/10197/7706/86/64750/580/7416/8239/7316/10213/5709/79155/7417/4792/9738/983/8314/55252/2099/9100/1643/4609/7415/9861/81847/5715/27430/5701/5688/9097/5687/6502/7347/4088/8078/5685/5683/5708/9146/54617/5692/5686/324/2033/408/5728/5710/8473/5702/7157/8900/9958/8975/4087/63891/7189/5704/6233/672/9804/7311/367/6881/79184/114548/7187/387/60/7040/8607/7345/1540/5694/7874/5693/154/7314/4193 104 Reovirus R-HSA-9613829 Chaperone Mediated Autophagy 16/2430 22/10654 9.146081810035747e-7 3.9801841362240255e-6 2.157553329437543e-6 1915/1080/10013/5116/7316/1068/3043/3920/3320/6233/3326/7311/7431/3312/11315/7314 16 Reovirus R-HSA-5628897 TP53 Regulates Metabolic Genes 40/2430 86/10654 1.015645828738375e-6 4.4055286597223026e-6 2.3881214291592686e-6 9377/27161/1329/7531/7532/207/10971/1345/9997/57690/27327/2810/192670/7534/1351/2539/54205/64223/1350/2821/10128/5728/192669/7157/8626/23112/2475/55004/5562/4343/1327/4697/9167/26523/5052/2744/57521/7248/7529/7296 40 Reovirus R-HSA-8878171 Transcriptional regulation by RUNX1 87/2430 239/10654 1.068968376785157e-6 4.621817965647152e-6 2.5053661837104e-6 1912/5718/9070/5689/27161/5684/4773/1437/11091/5682/6929/1459/5700/5707/640/8535/6045/9021/5690/57690/5717/5929/27327/80012/1460/143471/3958/5706/5705/10197/192670/200845/86/7316/10213/5709/7082/1457/1911/10413/6714/2099/9861/5715/5701/5688/1387/84733/5687/5685/5683/5708/5692/5686/10138/2033/84333/57332/595/50943/5710/5702/192669/3065/83737/861/5371/23112/26053/5704/6233/7311/860/4343/648/3276/5694/6601/23466/26523/5781/7057/1022/5693/7314/6015/55170 87 Reovirus R-HSA-72086 mRNA Capping 19/2430 29/10654 1.0762457340265702e-6 4.638271937611283e-6 2.514285449950018e-6 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/2068/5439/6829/1022/5432/22916 19 Reovirus R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 12/2430 14/10654 1.1034664128898645e-6 4.665288378547022e-6 2.528930353325205e-6 5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 12 Reovirus R-HSA-4839744 truncated APC mutants destabilize the destruction complex 12/2430 14/10654 1.1034664128898645e-6 4.665288378547022e-6 2.528930353325205e-6 5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 12 Reovirus R-HSA-4839748 AMER1 mutants destabilize the destruction complex 12/2430 14/10654 1.1034664128898645e-6 4.665288378547022e-6 2.528930353325205e-6 5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 12 Reovirus R-HSA-5467337 APC truncation mutants have impaired AXIN binding 12/2430 14/10654 1.1034664128898645e-6 4.665288378547022e-6 2.528930353325205e-6 5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 12 Reovirus R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 12/2430 14/10654 1.1034664128898645e-6 4.665288378547022e-6 2.528930353325205e-6 5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 12 Reovirus R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 12/2430 14/10654 1.1034664128898645e-6 4.665288378547022e-6 2.528930353325205e-6 5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 12 Reovirus R-HSA-9006931 Signaling by Nuclear Receptors 104/2430 299/10654 1.2099820023530427e-6 5.099482508339638e-6 2.764295592292523e-6 5295/2788/5105/27161/3725/2963/3838/5434/5440/5590/6464/8841/5290/54331/1374/6801/59345/5160/5430/5165/207/5436/57690/5594/3315/10681/27327/10274/1737/51764/94235/5441/10735/5481/192670/200845/5438/348/5431/5885/2100/5435/5433/9611/55970/5469/1105/1655/2194/6667/2792/2289/6714/2099/4609/2962/1387/5437/2793/2171/3320/2033/5162/8243/2785/9126/595/2783/2784/2782/5439/192669/3065/861/23028/2786/23112/2771/10498/3326/7514/1025/1738/23030/1386/1956/5536/3169/5296/4343/3845/3276/3265/26523/801/29116/8877/5432/3480/2791/2288/10728/2790/2787 104 Reovirus R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 21/2430 34/10654 1.2236003524892607e-6 5.124545676882922e-6 2.7778816779825485e-6 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/5435/5433/2962/5437/5439/1025/11198/6829/51497/5432/25920 21 Reovirus R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 21/2430 34/10654 1.2236003524892607e-6 5.124545676882922e-6 2.7778816779825485e-6 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/5435/5433/2962/5437/5439/1025/11198/6829/51497/5432/25920 21 Reovirus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 26/2430 47/10654 1.3561697271447078e-6 5.6620086108291545e-6 3.069226224590654e-6 8454/8841/79885/2648/9734/23462/6500/3091/10013/7316/9978/9611/9759/1024/4609/10014/22938/1387/2033/55294/3066/3065/6233/7311/4851/7314 26 Reovirus R-HSA-5368287 Mitochondrial translation 42/2430 93/10654 1.4575250614064337e-6 6.066210224420546e-6 3.288333307911547e-6 51264/6182/122704/29088/29093/65993/64979/92399/79590/4528/6183/65003/28998/64983/55052/63931/51023/219927/64963/64960/64968/11222/64969/51081/51069/65008/85476/55173/51116/54948/55168/9801/63875/65005/84340/54998/64965/51073/9553/7284/51021/29074 42 Reovirus R-HSA-397795 G-protein beta:gamma signalling 20/2430 32/10654 1.6857034393053603e-6 6.972445185485948e-6 3.7795794891383012e-6 2788/54331/59345/207/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/998/2786/387/2791/2790/2787 20 Reovirus R-HSA-5656169 Termination of translesion DNA synthesis 20/2430 32/10654 1.6857034393053603e-6 6.972445185485948e-6 3.7795794891383012e-6 6118/9636/7706/7316/5111/5426/9100/6119/5429/5985/5984/9246/6233/7311/7318/6117/5981/5424/7314/56655 20 Reovirus R-HSA-382556 ABC-family proteins mediated transport 45/2430 103/10654 1.921277239810565e-6 7.922303680206527e-6 4.29447284272147e-6 5718/5689/5684/1965/5682/5700/5707/5243/6048/5690/5717/1080/23/143471/5706/5705/10197/5824/7316/10213/5709/7415/9861/5715/22/5701/5688/5687/5685/8894/5683/5708/5692/5686/5710/5702/10613/5704/6233/7311/11160/5694/5693/7314/1968 45 Reovirus R-HSA-202040 G-protein activation 18/2430 28/10654 3.1332939049066633e-6 1.2840738211519332e-5 6.9606270796764096e-6 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2771/2791/2790/2787 18 Reovirus R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 18/2430 28/10654 3.1332939049066633e-6 1.2840738211519332e-5 6.9606270796764096e-6 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2771/2791/2790/2787 18 Reovirus R-HSA-2514853 Condensation of Prometaphase Chromosomes 10/2430 11/10654 3.2775835218746183e-6 1.3350157272025885e-5 7.236769778721877e-6 64151/1459/1460/9133/10051/891/1457/983/9918/10592 10 Reovirus R-HSA-77588 SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs 10/2430 11/10654 3.2775835218746183e-6 1.3350157272025885e-5 7.236769778721877e-6 6635/7884/134353/84967/6637/4686/6636/6634/22916/6628 10 Reovirus R-HSA-167169 HIV Transcription Elongation 25/2430 46/10654 3.3449701246660506e-6 1.3501148297745752e-5 7.3186180498338136e-6 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/5435/4686/5433/2962/5437/2068/5439/1025/11198/6829/51497/1022/5432/22916/25920 25 Reovirus R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 25/2430 46/10654 3.3449701246660506e-6 1.3501148297745752e-5 7.3186180498338136e-6 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/5435/4686/5433/2962/5437/2068/5439/1025/11198/6829/51497/1022/5432/22916/25920 25 Reovirus R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 25/2430 46/10654 3.3449701246660506e-6 1.3501148297745752e-5 7.3186180498338136e-6 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/5435/4686/5433/2962/5437/2068/5439/1025/11198/6829/51497/1022/5432/22916/25920 25 Reovirus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 14/2430 19/10654 3.5513964212554173e-6 1.4248245101493207e-5 7.723599613793984e-6 5295/6464/5290/7316/867/3320/6233/2885/7311/1956/3845/3265/11140/7314 14 Reovirus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 14/2430 19/10654 3.5513964212554173e-6 1.4248245101493207e-5 7.723599613793984e-6 5295/6464/5290/7316/867/3320/6233/2885/7311/1956/3845/3265/11140/7314 14 Reovirus R-HSA-196299 Beta-catenin phosphorylation cascade 13/2430 17/10654 4.077717888156723e-6 1.6262182383813077e-5 8.815302143132207e-6 1499/5525/5526/1452/5528/5519/2932/324/5529/5527/5518/5515/5516 13 Reovirus R-HSA-8934593 Regulation of RUNX1 Expression and Activity 13/2430 17/10654 4.077717888156723e-6 1.6262182383813077e-5 8.815302143132207e-6 27161/57690/27327/192670/6714/595/192669/861/5371/23112/4343/26523/5781 13 Reovirus R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 11/2430 13/10654 4.1763345967715274e-6 1.660590184906774e-5 9.00162344166294e-6 7531/7532/10971/2810/11200/7534/891/983/1111/7465/7529 11 Reovirus R-HSA-5389840 Mitochondrial translation elongation 39/2430 87/10654 4.284538659741846e-6 1.6935336240873096e-5 9.180201176899377e-6 51264/6182/122704/29088/29093/65993/64979/79590/6183/65003/28998/64983/55052/63931/51023/219927/64963/64960/64968/11222/64969/51081/51069/65008/85476/55173/51116/54948/55168/9801/63875/65005/54998/64965/51073/9553/7284/51021/29074 39 Reovirus R-HSA-5419276 Mitochondrial translation termination 39/2430 87/10654 4.284538659741846e-6 1.6935336240873096e-5 9.180201176899377e-6 51264/6182/122704/29088/29093/65993/64979/92399/79590/6183/65003/28998/64983/55052/63931/51023/219927/64963/64960/64968/11222/64969/51081/51069/65008/55173/51116/54948/55168/9801/63875/65005/84340/54998/64965/51073/9553/51021/29074 39 Reovirus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 38/2430 84/10654 4.336287436620242e-6 1.708932157912874e-5 9.263672586227997e-6 6118/83444/7515/6613/7336/86/8450/54778/7316/9978/5111/5426/1643/10980/6119/7341/1642/54617/5985/142/2068/10987/5984/1069/7329/6233/7311/60/8533/8607/6117/7334/5981/5424/1022/7314/8451/56655 38 Reovirus R-HSA-430039 mRNA decay by 5' to 3' exoribonuclease 12/2430 15/10654 4.36367173605203e-6 1.7146663056957387e-5 9.294755895986986e-6 1656/80153/27257/27258/25804/51690/11157/57819/23658/55802/54464/167227 12 Reovirus R-HSA-167287 HIV elongation arrest and recovery 21/2430 36/10654 4.528780748216324e-6 1.769137742578073e-5 9.59003125507181e-6 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/5435/5433/2962/5437/5439/1025/11198/6829/51497/5432/25920 21 Reovirus R-HSA-167290 Pausing and recovery of HIV elongation 21/2430 36/10654 4.528780748216324e-6 1.769137742578073e-5 9.59003125507181e-6 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/5435/5433/2962/5437/5439/1025/11198/6829/51497/5432/25920 21 Reovirus R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 19/2430 31/10654 4.6866741790464775e-6 1.8201734602343295e-5 9.866682482203108e-6 23165/4928/81929/5903/7175/9631/348995/79023/57122/23279/9688/79902/23225/8086/8021/6396/129401/55746/8480 19 Reovirus R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 19/2430 31/10654 4.6866741790464775e-6 1.8201734602343295e-5 9.866682482203108e-6 23165/4928/81929/5903/7175/9631/348995/79023/57122/23279/9688/79902/23225/8086/8021/6396/129401/55746/8480 19 Reovirus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 24/2430 44/10654 4.82340971870088e-6 1.8678479374447465e-5 1.0125113307295821e-5 7027/7321/6497/64750/7323/8239/54778/7316/9611/1024/6667/4609/22938/23327/4088/142/5494/3065/6498/4087/6233/1025/7311/7314 24 Reovirus R-HSA-9612973 Autophagy 49/2430 119/10654 5.368158338755659e-6 2.072791774733399e-5 1.12360600458287e-5 65018/1459/1915/8878/60673/10452/1080/1460/10533/10013/5116/7416/100188893/26100/79720/192111/7316/8655/1457/1068/6714/64223/3043/56993/3920/3320/55054/81631/6233/3326/2475/55004/9804/7311/23710/84557/54543/5562/11345/55626/7251/7431/3312/11315/401505/57521/7248/140735/7314 49 Reovirus R-HSA-112382 Formation of RNA Pol II elongation complex 30/2430 61/10654 5.528905459077613e-6 2.1225912911861182e-5 1.1506010150772527e-5 85403/2963/6917/5434/5440/6830/5430/5436/79577/6749/5441/5438/5431/5435/4686/5433/2962/5437/2068/5439/1025/23168/11198/6829/51497/1022/5432/22916/123169/25920 30 Reovirus R-HSA-75955 RNA Polymerase II Transcription Elongation 30/2430 61/10654 5.528905459077613e-6 2.1225912911861182e-5 1.1506010150772527e-5 85403/2963/6917/5434/5440/6830/5430/5436/79577/6749/5441/5438/5431/5435/4686/5433/2962/5437/2068/5439/1025/23168/11198/6829/51497/1022/5432/22916/123169/25920 30 Reovirus R-HSA-3371571 HSF1-dependent transactivation 16/2430 24/10654 5.594045805156517e-6 2.1414456148106322e-5 1.1608214489361132e-5 3303/3337/3305/64223/1387/3320/2033/3326/2475/3306/3304/3312/3297/57521/2288/10728 16 Reovirus R-HSA-450294 MAP kinase activation 31/2430 64/10654 5.795429548841669e-6 2.212198250643563e-5 1.1991745953693439e-5 8454/3725/8945/5606/5594/6500/5528/7316/79155/7335/9261/5519/5598/1432/23291/6195/3654/7189/6233/6196/7311/5518/1386/6197/5599/5600/7334/51231/7314/5515/5516 31 Reovirus R-HSA-1227986 Signaling by ERBB2 26/2430 50/10654 6.329089055385695e-6 2.409020791451649e-5 1.3058669276069448e-5 5295/8065/6464/5290/2065/10273/207/10193/2064/7316/5753/6714/3320/2886/6233/2885/7525/5580/7311/387/1956/5581/3845/3265/11140/7314 26 Reovirus R-HSA-5205685 Pink/Parkin Mediated Mitophagy 15/2430 22/10654 7.308175267888726e-6 2.765926956911994e-5 1.4993363901319348e-5 65018/8878/10452/7416/100188893/7316/56993/81631/6233/9804/7311/84557/54543/401505/7314 15 Reovirus R-HSA-71403 Citric acid cycle (TCA cycle) 15/2430 22/10654 7.308175267888726e-6 2.765926956911994e-5 1.4993363901319348e-5 4967/3419/1743/8802/3420/6389/50/8803/6390/23530/1431/8801/1738/4191/3421 15 Reovirus R-HSA-4086398 Ca2+ pathway 30/2430 62/10654 8.391766310828552e-6 3.167062087928516e-5 1.7167812137526148e-5 2788/27161/54331/1499/59345/4772/57690/10681/27327/51764/94235/192670/55970/2792/6934/2793/2785/2783/2784/2782/192669/2786/23112/4343/3845/26523/801/2791/2790/2787 30 Reovirus R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 17/2430 27/10654 8.956624222056208e-6 3.361249988951431e-5 1.8220453769292342e-5 2963/5434/5440/5430/5436/5441/5438/5431/5435/5433/2962/5437/2068/5439/6829/1022/5432 17 Reovirus R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 17/2430 27/10654 8.956624222056208e-6 3.361249988951431e-5 1.8220453769292342e-5 2963/5434/5440/5430/5436/5441/5438/5431/5435/5433/2962/5437/2068/5439/6829/1022/5432 17 Reovirus R-HSA-5673000 RAF activation 19/2430 32/10654 9.072708337129627e-6 3.395276845491648e-5 1.8404904425608677e-5 5525/5526/8844/5528/6714/5519/5529/5894/5527/5518/4140/3845/3265/369/801/5245/7529/5515/5516 19 Reovirus R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 25/2430 48/10654 9.176101265885099e-6 3.424377455648741e-5 1.8562651193557623e-5 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/5435/4686/5433/2962/5437/2068/5439/1025/11198/6829/51497/1022/5432/22916/25920 25 Reovirus R-HSA-1236975 Antigen processing-Cross presentation 42/2430 99/10654 1.0274035226408486e-5 3.823429265315247e-5 2.0725806291655294e-5 5718/5689/5684/10952/5682/5700/3107/5707/5690/55176/5717/811/143471/5706/5705/10197/9554/23480/7316/10213/5709/29927/9861/5715/5701/5688/5687/5685/5683/5708/5692/5686/2923/5710/5702/5704/6233/7311/5694/3105/5693/7314 42 Reovirus R-HSA-5684996 MAPK1/MAPK3 signaling 88/2430 255/10654 1.1221026511919126e-5 4.1642476166455426e-5 2.257329310000105e-5 5718/5689/5684/6464/1437/3667/71/5682/2065/5525/5700/5707/5526/8844/10048/7094/84292/5690/5594/2322/5717/409/7414/143471/5706/2064/5705/10197/2260/8452/5528/4684/7316/10213/5709/9978/3560/983/84078/3718/6714/9861/5715/5519/2261/5701/5688/5687/5685/5683/5708/5692/5686/2335/408/80824/5529/1445/5710/5702/5894/5704/6233/5527/2885/6709/7311/8826/5518/1956/60/5536/4140/2253/3845/5694/3265/369/801/7297/5781/5693/5245/7529/7314/11221/5515/5516 88 Reovirus R-HSA-5368286 Mitochondrial translation initiation 38/2430 87/10654 1.194216769755338e-5 4.419594472003135e-5 2.3957461367303473e-5 51264/6182/122704/29088/29093/65993/64979/79590/4528/6183/65003/28998/64983/55052/63931/51023/219927/64963/64960/64968/11222/64969/51081/51069/65008/55173/51116/54948/55168/9801/63875/65005/54998/64965/51073/9553/51021/29074 38 Reovirus R-HSA-1226099 Signaling by FGFR in disease 30/2430 63/10654 1.2551734033889177e-5 4.6323526710707015e-5 2.5110767709554387e-5 5295/2963/8805/5434/5440/11052/26127/5290/5430/5436/5441/2260/5438/5431/5435/4686/5433/6774/2962/2261/5437/11064/5439/2885/11160/2253/3845/3265/5432/22916 30 Reovirus R-HSA-111367 SLBP independent Processing of Histone Pre-mRNAs 9/2430 10/10654 1.3134281744705116e-5 4.833994603560891e-5 2.6203815689015857e-5 6635/134353/84967/6637/4686/6636/6634/22916/6628 9 Reovirus R-HSA-110312 Translesion synthesis by REV1 12/2430 16/10654 1.381080538173633e-5 5.0551331479451334e-5 2.740254968315673e-5 6118/7316/5111/10459/6119/5985/5984/6233/7311/6117/5981/7314 12 Reovirus R-HSA-1295596 Spry regulation of FGF signaling 12/2430 16/10654 1.381080538173633e-5 5.0551331479451334e-5 2.740254968315673e-5 5594/7316/6714/867/6233/2885/7311/5518/5781/7314/5515/5516 12 Reovirus R-HSA-5693532 DNA Double-Strand Break Repair 62/2430 166/10654 1.464562551336932e-5 5.346053466082353e-5 2.8979552353172537e-5 8467/51750/1017/6118/3838/5893/151987/5888/5883/322/7486/10111/7520/7515/5531/51548/11200/545/472/6613/7336/580/11073/5591/7316/9031/8314/641/5111/5426/7517/9656/6119/22976/7341/5429/5985/165918/142/1111/7157/8900/5984/7329/8924/6233/672/7311/6047/79184/23030/5536/7156/6117/5599/7334/5981/2547/5424/55183/7314/56655 62 Reovirus R-HSA-157858 Gap junction trafficking and regulation 25/2430 49/10654 1.4698794606354587e-5 5.3508418512506074e-5 2.900550893208649e-5 1173/84617/79861/71/51807/10382/347688/1601/7277/2697/10381/7278/112714/7082/6714/7846/113457/347733/10376/81027/1213/10383/60/84790/7280 25 Reovirus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 40/2430 94/10654 1.51900957863398e-5 5.5146652093885796e-5 2.9893552348403266e-5 8454/3665/3725/8945/351/5606/7321/5594/6500/841/5528/7323/7316/79155/7335/4792/9261/7322/5519/5598/1432/23291/6195/3654/7189/6233/6196/7311/5518/7187/1386/9641/6197/5599/5600/7334/51231/7314/5515/5516 40 Reovirus R-HSA-2559585 Oncogene Induced Senescence 19/2430 33/10654 1.6822387218593143e-5 6.074245763254173e-5 3.2926891625582025e-5 1019/1029/7027/57690/5594/27327/5925/192670/7316/6667/192669/7157/23112/6233/7311/4343/26523/7314/4193 19 Reovirus R-HSA-9022692 Regulation of MECP2 expression and activity 19/2430 33/10654 1.6822387218593143e-5 6.074245763254173e-5 3.2926891625582025e-5 27161/8841/2290/9212/3930/57690/27327/192670/9611/5566/3064/192669/3066/3065/4204/23112/4343/26523/801 19 Reovirus R-HSA-1236394 Signaling by ERBB4 28/2430 58/10654 1.7611075759960372e-5 6.341886041861741e-5 3.437769931295995e-5 5295/6464/5290/2065/51741/23385/348/7316/9611/11059/4734/10413/6714/2099/5664/83737/3925/83464/6233/2885/7311/1956/3845/55851/51107/3265/5663/7314 28 Reovirus R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic 72/2430 202/10654 2.0364121921484166e-5 7.313566367500765e-5 3.964492326536815e-5 22820/400/84617/79861/11258/10618/1783/51807/10382/5050/347688/29127/3798/84316/5861/55860/830/7277/10381/55605/7278/112714/1780/9554/5048/1781/8655/1315/23303/1639/832/10121/9367/3796/5870/9183/10112/11316/1062/6836/7846/113457/89953/2590/547/347733/51560/8729/10376/10972/51143/1314/10540/81027/381/11004/9276/3833/3799/10383/84790/84643/378/5049/375/22920/81930/140735/7280/54732/829/1778 72 Reovirus R-HSA-199977 ER to Golgi Anterograde Transport 58/2430 154/10654 2.0539679415271386e-5 7.356839597534202e-5 3.987949608496321e-5 9919/58485/22820/84617/79861/10342/11258/1783/51807/10484/10382/347688/5861/55860/830/7277/10381/7278/112714/1780/9554/1781/8655/1315/1639/832/3998/10282/10121/2804/11316/7846/113457/22870/347733/8729/10376/10972/51143/1314/10540/81027/381/9276/6709/5537/10383/84790/378/6396/375/1453/140735/1075/7280/54732/829/1778 58 Reovirus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 146/2430 473/10654 2.2027761549336617e-5 7.868740489281744e-5 4.265437643102615e-5 5295/1173/2963/5434/5440/5590/8065/6464/161/5290/23543/3667/71/5770/1499/2065/4690/526/10006/5430/10653/10048/10273/207/5436/2060/9114/5594/10193/2322/3315/3178/51741/23385/2064/382/5441/2260/5438/348/5431/6696/5528/9306/5435/3688/4686/7316/5433/5753/9611/527/3185/6774/11059/9261/4734/3915/10768/10413/6714/2099/8651/5664/64223/5566/2962/5519/5898/1003/5598/1432/2261/867/5437/4670/4914/529/55824/9146/3320/2335/64759/6195/3728/8471/1445/5439/1111/998/83737/2886/3925/30011/83464/6233/2885/7525/1398/3187/7410/5580/2475/7409/163/7073/6196/7311/5518/1213/387/1956/60/5296/5581/581/2253/6197/3845/5600/7059/55851/51107/3265/1399/523/801/1020/5781/7057/8877/5432/3480/22916/5663/5725/11140/51231/7529/5829/7314/5879/253260/5515/25920/5516 146 Reovirus R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 14/2430 21/10654 2.2134317488200987e-5 7.885719510463073e-5 4.274641524738885e-5 4849/4869/4850/9337/25904/246175/4848/23019/7157/55571/55835/57472/85456/29883 14 Reovirus R-HSA-5689880 Ub-specific processing proteases 77/2430 220/10654 2.2326688470941426e-5 7.933099946057912e-5 4.3003252150077546e-5 5718/5689/5684/5682/2648/7419/5700/5707/991/8237/5690/55611/9817/5717/409/6478/1080/3091/143471/5706/5705/57695/10197/64750/7416/8239/7316/10213/5709/7417/4792/9738/9100/1643/4609/9861/81847/5715/27430/5701/5688/9097/5687/6502/4088/8078/5685/5683/5708/9146/5692/5686/408/5728/5710/5702/7157/8900/9958/8975/4087/63891/7189/5704/6233/9804/7311/367/6881/8607/1540/5694/7874/5693/154/7314/4193 77 Reovirus R-HSA-5673001 RAF/MAP kinase cascade 85/2430 249/10654 2.4976615249503968e-5 8.85112943589849e-5 4.797964900644626e-5 5718/5689/5684/6464/1437/3667/71/5682/2065/5525/5700/5707/5526/8844/10048/7094/84292/5690/5594/2322/5717/409/7414/143471/5706/2064/5705/10197/2260/8452/5528/4684/7316/10213/5709/9978/3560/84078/3718/6714/9861/5715/5519/2261/5701/5688/5687/5685/5683/5708/5692/5686/2335/408/80824/5529/1445/5710/5702/5894/5704/6233/5527/2885/6709/7311/8826/5518/1956/60/5536/4140/2253/3845/5694/3265/369/801/5693/5245/7529/7314/11221/5515/5516 85 Reovirus R-HSA-166166 MyD88-independent TLR4 cascade 41/2430 99/10654 2.6079620858201603e-5 9.193238381677399e-5 4.983413178848133e-5 8454/3665/3725/8945/351/5606/7321/5594/6500/841/5528/7323/7316/79155/7335/4792/9261/7322/5519/5598/1432/23291/6195/3654/7189/6233/6196/7311/5518/7187/1386/9641/6197/5599/5600/7334/5781/51231/7314/5515/5516 41 Reovirus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 41/2430 99/10654 2.6079620858201603e-5 9.193238381677399e-5 4.983413178848133e-5 8454/3665/3725/8945/351/5606/7321/5594/6500/841/5528/7323/7316/79155/7335/4792/9261/7322/5519/5598/1432/23291/6195/3654/7189/6233/6196/7311/5518/7187/1386/9641/6197/5599/5600/7334/5781/51231/7314/5515/5516 41 Reovirus R-HSA-6804760 Regulation of TP53 Activity through Methylation 13/2430 19/10654 2.903957708885074e-5 1.020970394492226e-4 5.5344124756590886e-5 11200/472/7316/2033/7157/91875/6233/7311/10419/26013/10919/7314/4193 13 Reovirus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 19/2430 34/10654 3.000143815136716e-5 1.052018933601746e-4 5.7027184550740725e-5 7321/9636/7706/7323/7316/3093/7322/83737/9246/51191/6233/7311/7318/5094/7187/5300/9641/1540/7314 19 Reovirus R-HSA-3899300 SUMOylation of transcription cofactors 23/2430 45/10654 3.1024356926235326e-5 1.0850403364777591e-4 5.8817188110360706e-5 1912/1487/8535/6045/4869/80012/6613/1655/1911/7341/1387/84733/10521/2033/57332/7329/10155/7690/6294/648/7703/11315/6015 23 Reovirus R-HSA-4655427 SUMOylation of DNA methylation proteins 12/2430 17/10654 3.717021536632743e-5 1.289854746218531e-4 6.99196395681019e-5 1912/8535/6045/80012/1911/7341/84733/57332/7329/648/7703/6015 12 Reovirus R-HSA-5655862 Translesion synthesis by POLK 12/2430 17/10654 3.717021536632743e-5 1.289854746218531e-4 6.99196395681019e-5 6118/7316/5111/10459/6119/5985/5984/6233/7311/6117/5981/7314 12 Reovirus R-HSA-5656121 Translesion synthesis by POLI 12/2430 17/10654 3.717021536632743e-5 1.289854746218531e-4 6.99196395681019e-5 6118/7316/5111/10459/6119/5985/5984/6233/7311/6117/5981/7314 12 Reovirus R-HSA-1428517 The citric acid (TCA) cycle and respiratory electron transport 63/2430 174/10654 3.818251145119867e-5 1.3215501372746481e-4 7.163776350811203e-5 9377/4967/3419/3945/4722/4723/1329/4702/2110/5160/5165/7388/1743/1345/9997/4719/4704/2109/8802/3420/1737/4724/7416/6389/4714/1351/50/4715/54205/7385/8803/3939/6390/4728/4725/374291/1350/23530/682/10131/5162/10128/27089/4731/1431/8801/4696/2108/2739/7384/1738/28976/4716/4698/4191/3421/1327/4697/4720/9167/1537/6566/51079 63 Reovirus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 18/2430 32/10654 4.3200854721418546e-5 1.4875345852529686e-4 8.063534467806826e-5 57154/10273/4738/64750/7316/5501/23327/867/4088/9958/9040/4087/5499/6233/7514/7311/7040/7314 18 Reovirus R-HSA-451326 Activation of kainate receptors upon glutamate binding 18/2430 32/10654 4.3200854721418546e-5 1.4875345852529686e-4 8.063534467806826e-5 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/801/2791/2790/2787 18 Reovirus R-HSA-9607240 FLT3 Signaling 89/2430 267/10654 4.497997715359513e-5 1.5414972772666153e-4 8.356052054518052e-5 5295/5718/5689/5684/6464/5290/1437/3667/71/5682/2065/5525/5700/5707/5526/8844/10048/7094/84292/5690/5594/2322/5717/409/7414/143471/5706/2064/5705/10197/2260/8452/5528/4684/7316/10213/5709/9978/3560/84078/3718/6714/9861/5715/5519/2261/5701/5688/5687/5685/5683/5708/5692/5686/2335/408/80824/5529/1445/5710/5702/5894/5704/6233/5527/2885/6709/7311/8826/5518/1956/60/5536/5296/4140/2253/3845/5694/3265/369/801/5781/5693/5245/7529/7314/11221/5515/5516 89 Reovirus R-HSA-5655253 Signaling by FGFR2 in disease 22/2430 43/10654 4.511417929724899e-5 1.5414972772666153e-4 8.356052054518052e-5 5295/2963/5434/5440/5290/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/5439/2885/2253/3845/3265/5432/22916 22 Reovirus R-HSA-5696395 Formation of Incision Complex in GG-NER 22/2430 43/10654 4.511417929724899e-5 1.5414972772666153e-4 8.356052054518052e-5 6118/6613/7336/8450/54778/7316/9978/1643/6119/7341/1642/142/2068/1069/7329/6233/7311/6117/7334/1022/7314/8451 22 Reovirus R-HSA-912631 Regulation of signaling by CBL 14/2430 22/10654 4.8080066373747136e-5 1.6386471600848514e-4 8.882676064752425e-5 5295/5290/7316/6850/867/6233/2885/7525/1398/7409/7311/5296/1399/7314 14 Reovirus R-HSA-77286 mitochondrial fatty acid beta-oxidation of saturated fatty acids 9/2430 11/10654 5.748942374744218e-5 1.9543478403710626e-4 1.0594006572449504e-4 3030/34/37/1892/51102/3033/35/33/3032 9 Reovirus R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 20/2430 38/10654 5.9197425104896044e-5 2.0073035517802313e-4 1.0881065581664033e-4 1912/1459/8535/6045/80012/1460/86/1457/1911/84733/10138/2033/84333/57332/861/26053/648/6601/23466/6015 20 Reovirus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 41/2430 102/10654 5.956850895790543e-5 2.009685049690951e-4 1.089397505662917e-4 8454/7124/5718/5689/8945/5684/5682/5700/5707/5690/9039/5717/6500/143471/5706/5705/10197/7316/10213/5709/9861/5715/5701/5688/5687/23291/5685/5683/5708/5692/5686/5710/5702/9040/5704/6233/7311/7187/5694/5693/7314 41 Reovirus R-HSA-9006936 Signaling by TGF-beta family members 41/2430 102/10654 5.956850895790543e-5 2.009685049690951e-4 1.089397505662917e-4 4093/57154/5590/7027/7321/6497/10273/4738/64750/7323/8239/54778/7316/9611/5501/1024/6667/4609/22938/23327/867/4088/142/5494/3065/6498/9958/9040/4087/5499/657/6233/7514/1025/7311/8928/387/7040/57530/4090/7314 41 Reovirus R-HSA-5696400 Dual Incision in GG-NER 21/2430 41/10654 6.564904819503945e-5 2.2092475664627886e-4 1.1975751069385427e-4 6118/8450/7316/9978/5111/5426/1643/6119/1642/5985/142/2068/5984/6233/7311/6117/5981/5424/7314/8451/56655 21 Reovirus R-HSA-187037 Signaling by NTRK1 (TRKA) 34/2430 80/10654 6.679660581460981e-5 2.242217722822078e-4 1.2154473631433893e-4 5295/1173/6464/161/5290/3667/5594/5528/6774/9261/6714/5519/5898/5598/1432/4914/6195/2885/1398/163/6196/5518/1213/387/5296/6197/3845/5600/3265/1399/51231/7529/5515/5516 34 Reovirus R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 15/2430 25/10654 6.881065112202382e-5 2.2982757474755957e-4 1.245834946630326e-4 6118/7515/7316/5111/5426/6119/5985/5984/6233/7311/6117/5981/5424/7314/56655 15 Reovirus R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus 15/2430 25/10654 6.881065112202382e-5 2.2982757474755957e-4 1.245834946630326e-4 142678/4904/23385/7316/4854/5664/11060/83464/6233/7311/1956/55851/51107/5663/7314 15 Reovirus R-HSA-190828 Gap junction trafficking 23/2430 47/10654 7.498909474769992e-5 2.498389790097932e-4 1.3543115155904327e-4 1173/84617/79861/71/51807/10382/347688/1601/7277/2697/10381/7278/112714/7846/113457/347733/10376/81027/1213/10383/60/84790/7280 23 Reovirus R-HSA-446652 Interleukin-1 family signaling 52/2430 140/10654 8.245855188726103e-5 2.740413565208476e-4 1.4855062502863468e-4 8454/5718/5689/8945/5684/351/5682/1511/5700/5707/5690/8878/54472/5717/6500/143471/5706/5705/10197/7316/10213/5709/9978/79155/6774/7335/4792/9861/5715/5701/5688/5687/23291/4088/5685/5683/5708/5692/5686/5710/5702/3654/7189/5704/6233/7311/5599/7334/5694/5781/5693/7314 52 Reovirus R-HSA-611105 Respiratory electron transport 40/2430 100/10654 8.296103898889079e-5 2.7502716647433774e-4 1.490850067241919e-4 9377/4722/4723/1329/4702/2110/7388/1345/9997/4719/4704/2109/4724/6389/4714/1351/4715/54205/7385/6390/4728/4725/374291/1350/10131/10128/27089/4731/4696/2108/7384/28976/4716/4698/1327/4697/4720/9167/1537/51079 40 Reovirus R-HSA-674695 RNA Polymerase II Pre-transcription Events 35/2430 84/10654 8.562824913030958e-5 2.831666852428059e-4 1.5349722616376493e-4 6884/85403/2963/6917/5434/5440/6830/5430/6874/5436/79577/6749/5441/5438/5431/5435/4686/5433/8148/2962/5437/2068/5439/1025/23168/6881/6880/11198/6829/51497/1022/5432/22916/123169/25920 35 Reovirus R-HSA-8955332 Carboxyterminal post-translational modifications of tubulin 20/2430 39/10654 9.560548041749678e-5 3.1538005392043385e-4 1.709592476341463e-4 84617/79861/164395/51807/10382/347688/7277/10381/7278/112714/7846/113457/347733/150465/10376/81027/10383/26140/84790/7280 20 Reovirus R-HSA-448424 Interleukin-17 signaling 31/2430 72/10654 1.0313608376276227e-4 3.389556239592606e-4 1.8373894522846778e-4 8454/3725/8945/5606/5594/6500/5528/7316/79155/7335/9261/5519/5598/1432/23291/6195/3654/7189/6233/6196/7311/5518/1386/6197/5599/5600/7334/51231/7314/5515/5516 31 Reovirus R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 21/2430 42/10654 1.0325968484387655e-4 3.389556239592606e-4 1.8373894522846778e-4 2788/54331/59345/10681/51764/94235/5573/55970/2792/5566/2793/2785/2783/2784/2782/2786/5577/8826/2791/2790/2787 21 Reovirus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 17/2430 31/10654 1.0851707768907055e-4 3.5534023478578006e-4 1.9262061261630684e-4 3725/5594/5528/9261/5519/5598/1432/6195/6196/5518/1386/6197/5599/5600/51231/5515/5516 17 Reovirus R-HSA-5619115 Disorders of transmembrane transporters 62/2430 176/10654 1.0995011722206478e-4 3.591524611459133e-4 1.946871204446804e-4 5718/23165/5689/4928/81929/5684/5903/7175/5682/9631/5700/5707/6048/5690/5717/1080/348995/143471/79023/5706/57122/5705/10197/7316/10213/5709/23279/9688/7415/9861/79902/5715/5701/5688/5687/23225/5685/5683/682/5708/5692/6521/5686/5710/5702/8086/6520/10613/5704/6233/7311/11160/8021/6396/129401/5694/55746/55630/5693/6566/8480/7314 62 Reovirus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 15/2430 26/10654 1.2841934647489302e-4 4.1845913875721236e-4 2.2683571341393168e-4 57154/10273/64750/7316/5501/23327/4088/9958/4087/5499/6233/7514/7311/7040/7314 15 Reovirus R-HSA-389513 CTLA4 inhibitory signaling 13/2430 21/10654 1.362762901402554e-4 4.4298083607635327e-4 2.4012828176846125e-4 5525/5526/207/5528/6714/5519/5529/5527/7525/5518/5781/5515/5516 13 Reovirus R-HSA-373760 L1CAM interactions 45/2430 119/10654 1.4972784430958028e-4 4.8552524271261953e-4 2.631904876979847e-4 1173/84617/161/79861/71/7430/1459/51807/10048/10382/5594/347688/1460/7277/10381/2260/7278/112714/4684/3688/1457/3915/6714/7846/113457/347733/1808/10376/6195/6386/81027/1641/7410/6709/163/6196/1213/10383/1956/60/84790/6197/3312/7280/5879 45 Reovirus R-HSA-5685942 HDR through Homologous Recombination (HRR) 29/2430 67/10654 1.525803525819361e-4 4.92384905916586e-4 2.6690893103577934e-4 51750/6118/5888/5883/7486/10111/545/472/580/11073/7316/641/5111/5426/7517/6119/5429/5985/1111/5984/6233/672/7311/7156/6117/5981/5424/7314/56655 29 Reovirus R-HSA-6802952 Signaling by BRAF and RAF fusions 29/2430 67/10654 1.525803525819361e-4 4.92384905916586e-4 2.6690893103577934e-4 4000/27044/8805/71/8087/10142/8844/7094/5594/409/7414/10533/8546/6714/2335/408/1445/5894/56829/8826/60/4140/9444/3845/3265/369/801/9715/7529 29 Reovirus R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 21/2430 43/10654 1.5876221286565762e-4 5.110995575626953e-4 2.770536523819212e-4 2788/54331/59345/10681/51764/94235/5573/8766/55970/2792/5566/2793/2785/2783/2784/2782/2786/5577/2791/2790/2787 21 Reovirus R-HSA-71406 Pyruvate metabolism and Citric Acid (TCA) cycle 25/2430 55/10654 1.6797607272919289e-4 5.394616181879848e-4 2.9242798086458676e-4 4967/3419/3945/5160/5165/1743/8802/3420/1737/7416/6389/50/8803/3939/6390/23530/682/5162/1431/8801/2739/1738/4191/3421/6566 25 Reovirus R-HSA-449147 Signaling by Interleukins 138/2430 461/10654 1.7819372980668255e-4 5.709036523302828e-4 3.094718821330243e-4 5295/8454/7124/5718/5689/3725/8945/5684/351/1072/6464/5290/1437/3667/6627/5606/5682/1511/5657/7412/5700/7184/5707/207/9021/5690/5594/8878/54472/5717/821/6500/3091/143471/5706/3383/5705/301/9987/10197/6657/7534/3313/332/5528/3688/7316/10213/5709/9978/6175/3560/79155/3185/6774/920/7335/4792/6850/1026/9261/3718/8651/4609/6647/9861/5566/5715/5519/5898/5598/1432/5701/867/5688/79923/5687/6950/23291/4088/3636/598/5685/5683/5708/3320/5692/5686/4843/2335/595/6195/5710/3181/5702/998/7157/5478/4001/3654/7189/5704/6233/2885/7525/1398/6844/7409/6196/7311/3594/3575/5518/302/1386/5296/7040/6197/8835/5599/5600/7431/4282/375/7334/5694/3312/1399/7297/5781/5693/5034/51231/4692/829/7314/5515/5516 138 Reovirus R-HSA-6802957 Oncogenic MAPK signaling 30/2430 71/10654 1.99332589404447e-4 6.371012905367014e-4 3.4535588393417156e-4 4000/27044/8805/71/8087/10142/8844/7094/5594/409/7414/10533/8546/6714/2335/408/1445/5894/56829/8826/60/4140/9444/3845/3265/369/801/9715/5245/7529 30 Reovirus R-HSA-5696394 DNA Damage Recognition in GG-NER 19/2430 38/10654 2.1950763464391145e-4 6.999097849266485e-4 3.7940271984678075e-4 83444/86/8450/7316/9978/1643/10980/1642/54617/142/10987/1069/6233/7311/60/8533/8607/7314/8451 19 Reovirus R-HSA-69231 Cyclin D associated events in G1 21/2430 44/10654 2.389700554157991e-4 7.583467791817282e-4 4.1107988030021197e-4 8454/1019/1029/7027/6500/5925/7316/5753/1026/6714/5519/6502/595/5520/6233/7311/5518/1022/7314/5515/5516 21 Reovirus R-HSA-69236 G1 Phase 21/2430 44/10654 2.389700554157991e-4 7.583467791817282e-4 4.1107988030021197e-4 8454/1019/1029/7027/6500/5925/7316/5753/1026/6714/5519/6502/595/5520/6233/7311/5518/1022/7314/5515/5516 21 Reovirus R-HSA-166520 Signaling by NTRKs 39/2430 101/10654 2.439983677511101e-4 7.724687661504338e-4 4.1873503869484593e-4 5295/1173/6464/161/5290/3667/5594/5528/6774/9261/6714/5519/5898/5598/1432/4914/6195/2885/1398/163/6196/5518/1213/387/5296/581/6197/3845/5600/3265/1399/1020/5781/51231/7529/5879/5515/25920/5516 39 Reovirus R-HSA-432142 Platelet sensitization by LDL 11/2430 17/10654 2.6204597954415784e-4 8.276440394113354e-4 4.4864410582650386e-4 5525/5526/5528/5519/1432/5529/5527/5518/5781/5515/5516 11 Reovirus R-HSA-198753 ERK/MAPK targets 13/2430 22/10654 2.636708355807658e-4 8.308118781507149e-4 4.503613080426188e-4 5594/5528/5519/5598/1432/6195/6196/5518/6197/5600/51231/5515/5516 13 Reovirus R-HSA-163359 Glucagon signaling in metabolic regulation 17/2430 33/10654 2.969596897129863e-4 9.291291462682662e-4 5.036565179897314e-4 2788/54331/59345/51764/94235/5573/55970/5566/2785/2783/2784/2782/2786/5577/2791/2790/2787 17 Reovirus R-HSA-1839126 FGFR2 mutant receptor activation 17/2430 33/10654 2.969596897129863e-4 9.291291462682662e-4 5.036565179897314e-4 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/5439/2253/5432/22916 17 Reovirus R-HSA-420092 Glucagon-type ligand receptors 17/2430 33/10654 2.969596897129863e-4 9.291291462682662e-4 5.036565179897314e-4 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Reovirus R-HSA-190861 Gap junction assembly 18/2430 36/10654 3.205314124818539e-4 9.982050514586406e-4 5.411007527604355e-4 84617/79861/51807/10382/347688/7277/2697/10381/7278/112714/7846/113457/347733/10376/81027/10383/84790/7280 18 Reovirus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 18/2430 36/10654 3.205314124818539e-4 9.982050514586406e-4 5.411007527604355e-4 71/8844/7094/5594/409/7414/6714/2335/408/1445/5894/8826/60/4140/3845/3265/369/7529 18 Reovirus R-HSA-1643713 Signaling by EGFR in Cancer 14/2430 25/10654 3.310543692121106e-4 0.0010238162899707864 5.549839327922321e-4 5295/6464/5290/7316/867/3320/6233/2885/7311/1956/3845/3265/11140/7314 14 Reovirus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 14/2430 25/10654 3.310543692121106e-4 0.0010238162899707864 5.549839327922321e-4 5594/5528/9261/5519/5598/1432/6195/6196/5518/6197/5600/51231/5515/5516 14 Reovirus R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 14/2430 25/10654 3.310543692121106e-4 0.0010238162899707864 5.549839327922321e-4 1017/9133/891/983/5519/5520/8900/7514/5518/5347/7465/1022/5515/5516 14 Reovirus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 22/2430 48/10654 3.529539517725035e-4 0.001089021892766893 5.903301782411144e-4 5295/6464/5290/1437/7534/7316/3560/6850/3718/5566/867/3636/6233/2885/7525/1398/7409/7311/5296/1399/5781/7314 22 Reovirus R-HSA-5637810 Constitutive Signaling by EGFRvIII 10/2430 15/10654 3.564006033238515e-4 0.0010939351568962966 5.929935297389316e-4 5295/6464/5290/867/3320/2885/1956/3845/3265/11140 10 Reovirus R-HSA-5637812 Signaling by EGFRvIII in Cancer 10/2430 15/10654 3.564006033238515e-4 0.0010939351568962966 5.929935297389316e-4 5295/6464/5290/867/3320/2885/1956/3845/3265/11140 10 Reovirus R-HSA-167172 Transcription of the HIV genome 30/2430 73/10654 3.570027907236417e-4 0.0010939351568962966 5.929935297389316e-4 6884/2963/6917/5434/5440/5430/6874/5436/6749/5441/5438/5431/5435/4686/5433/8148/2962/5437/2068/5439/1025/6881/6880/11198/6829/51497/1022/5432/22916/25920 30 Reovirus R-HSA-8876384 Listeria monocytogenes entry into host cells 12/2430 20/10654 3.763660103935245e-4 0.0011506292674731092 6.23725918705877e-4 1499/2060/7316/6714/867/999/9146/30011/6233/2885/7311/7314 12 Reovirus R-HSA-2995383 Initiation of Nuclear Envelope Reformation 9/2430 13/10654 4.7430292302355013e-4 0.0014401561480896885 7.806708398090967e-4 4000/7443/7444/5520/2010/4001/5518/7112/5515 9 Reovirus R-HSA-2995410 Nuclear Envelope Reassembly 9/2430 13/10654 4.7430292302355013e-4 0.0014401561480896885 7.806708398090967e-4 4000/7443/7444/5520/2010/4001/5518/7112/5515 9 Reovirus R-HSA-68884 Mitotic Telophase/Cytokinesis 9/2430 13/10654 4.7430292302355013e-4 0.0014401561480896885 7.806708398090967e-4 10274/23244/10735/23047/5885/10112/8243/9126/5347 9 Reovirus R-HSA-5654741 Signaling by FGFR3 19/2430 40/10654 5.06162826303047e-4 0.001529940126563056 8.293403774624824e-4 5295/6464/5290/5594/7316/6714/2261/867/6233/2885/7311/5518/2253/3845/3265/5781/7314/5515/5516 19 Reovirus R-HSA-5674135 MAP2K and MAPK activation 19/2430 40/10654 5.06162826303047e-4 0.001529940126563056 8.293403774624824e-4 71/8844/7094/84292/5594/409/7414/6714/2335/408/1445/5894/8826/60/4140/3845/3265/369/7529 19 Reovirus R-HSA-438064 Post NMDA receptor activation events 32/2430 81/10654 5.338222915124442e-4 0.0016099019897531047 8.726856042783926e-4 84617/3838/79861/51807/10382/5594/347688/7277/10381/7278/5573/112714/6714/5566/7846/113457/347733/10376/6195/4137/81027/5577/6196/5562/10383/84790/6197/3845/3265/801/7280/5879 32 Reovirus R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 11/2430 18/10654 5.350595753505395e-4 0.001609999082586308 8.727382357543175e-4 7027/2810/891/983/6790/5111/2033/7157/10498/581/3276 11 Reovirus R-HSA-9018519 Estrogen-dependent gene expression 52/2430 150/10654 5.876067309628576e-4 0.0017641406574525342 9.562943368478912e-4 27161/3725/2963/3838/5434/5440/5430/5436/57690/27327/10274/5441/10735/192670/200845/5438/5431/5885/5435/5433/5469/1105/1655/6667/2099/4609/2962/1387/5437/3320/2033/8243/9126/595/5439/192669/3065/861/23028/23112/10498/3326/1025/23030/1386/3169/4343/3276/26523/5432/2288/10728 52 Reovirus R-HSA-8986944 Transcriptional Regulation by MECP2 26/2430 62/10654 5.974831163758884e-4 0.0017897700526416749 9.701873591376238e-4 27161/8841/2290/5770/5468/9212/3930/57690/27327/6657/192670/54487/9611/2289/5566/3064/5728/192669/3066/3065/4204/3654/23112/4343/26523/801 26 Reovirus R-HSA-2468052 Establishment of Sister Chromatid Cohesion 8/2430 11/10654 6.095906834517562e-4 0.0018219533626209086 9.876330865767296e-4 10274/23244/10735/23047/5885/8243/9126/113130 8 Reovirus R-HSA-1632852 Macroautophagy 36/2430 95/10654 6.306161523828485e-4 0.0018805874544274232 0.0010194170884384394 65018/1459/8878/60673/10452/1460/10533/7416/100188893/26100/192111/7316/8655/1457/6714/64223/56993/55054/81631/6233/2475/55004/9804/7311/23710/84557/54543/5562/11345/55626/3312/401505/57521/7248/140735/7314 36 Reovirus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 33/2430 85/10654 6.353400536598238e-4 0.0018820716445444006 0.0010202216289367692 8454/3725/8945/351/5606/5594/6500/5528/7316/79155/7335/4792/9261/5519/5598/1432/23291/6195/3654/7189/6233/6196/7311/5518/1386/6197/5599/5600/7334/51231/7314/5515/5516 33 Reovirus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 33/2430 85/10654 6.353400536598238e-4 0.0018820716445444006 0.0010202216289367692 8454/3725/8945/351/5606/5594/6500/5528/7316/79155/7335/4792/9261/5519/5598/1432/23291/6195/3654/7189/6233/6196/7311/5518/1386/6197/5599/5600/7334/51231/7314/5515/5516 33 Reovirus R-HSA-975871 MyD88 cascade initiated on plasma membrane 33/2430 85/10654 6.353400536598238e-4 0.0018820716445444006 0.0010202216289367692 8454/3725/8945/351/5606/5594/6500/5528/7316/79155/7335/4792/9261/5519/5598/1432/23291/6195/3654/7189/6233/6196/7311/5518/1386/6197/5599/5600/7334/51231/7314/5515/5516 33 Reovirus R-HSA-109606 Intrinsic Pathway for Apoptosis 23/2430 53/10654 6.847892867139019e-4 0.0020240674492251615 0.0010971938268727632 7531/1029/7027/7532/207/10971/5594/2810/841/7534/8655/6774/54205/4836/598/708/3002/7157/8626/581/5599/140735/7529 23 Reovirus R-HSA-167161 HIV Transcription Initiation 21/2430 47/10654 7.270019828005266e-4 0.0021206870065971694 0.0011495687523943054 6884/2963/5434/5440/5430/6874/5436/5441/5438/5431/5435/5433/8148/2962/5437/2068/5439/6881/6880/1022/5432 21 Reovirus R-HSA-167162 RNA Polymerase II HIV Promoter Escape 21/2430 47/10654 7.270019828005266e-4 0.0021206870065971694 0.0011495687523943054 6884/2963/5434/5440/5430/6874/5436/5441/5438/5431/5435/5433/8148/2962/5437/2068/5439/6881/6880/1022/5432 21 Reovirus R-HSA-73776 RNA Polymerase II Promoter Escape 21/2430 47/10654 7.270019828005266e-4 0.0021206870065971694 0.0011495687523943054 6884/2963/5434/5440/5430/6874/5436/5441/5438/5431/5435/5433/8148/2962/5437/2068/5439/6881/6880/1022/5432 21 Reovirus R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 21/2430 47/10654 7.270019828005266e-4 0.0021206870065971694 0.0011495687523943054 6884/2963/5434/5440/5430/6874/5436/5441/5438/5431/5435/5433/8148/2962/5437/2068/5439/6881/6880/1022/5432 21 Reovirus R-HSA-75953 RNA Polymerase II Transcription Initiation 21/2430 47/10654 7.270019828005266e-4 0.0021206870065971694 0.0011495687523943054 6884/2963/5434/5440/5430/6874/5436/5441/5438/5431/5435/5433/8148/2962/5437/2068/5439/6881/6880/1022/5432 21 Reovirus R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 21/2430 47/10654 7.270019828005266e-4 0.0021206870065971694 0.0011495687523943054 6884/2963/5434/5440/5430/6874/5436/5441/5438/5431/5435/5433/8148/2962/5437/2068/5439/6881/6880/1022/5432 21 Reovirus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 33/2430 86/10654 8.086022418602833e-4 0.002353578638617295 0.001275813192064843 5295/1072/5290/23646/71/4690/10093/10006/4771/5594/6850/10552/10768/10094/4641/6714/3320/998/2885/7525/1398/7410/10096/3326/5580/10097/7409/60/5296/5581/5338/10109/5879 33 Reovirus R-HSA-76002 Platelet activation, signaling and aggregation 82/2430 262/10654 8.483187079339556e-4 0.00246381259521688 0.0013355681259921313 5295/2788/5590/351/1072/6464/5290/54331/5005/5770/59345/51097/3937/2316/207/813/7094/3959/5594/10681/409/6915/7414/51764/7277/94235/7534/51706/55970/308/5216/6850/2792/6714/3671/6647/7273/22927/1432/3920/2793/374354/81/3309/9948/2335/408/2785/391/2783/2784/1445/2782/87/998/5894/5478/2786/2771/10487/2885/1398/5473/7410/5580/7409/8407/387/5296/5581/29789/7040/10916/801/5781/7057/2791/2147/5879/2790/2787/10672 82 Reovirus R-HSA-5620920 Cargo trafficking to the periciliary membrane 22/2430 51/10654 9.805505821008002e-4 0.0028416823810990654 0.001540401416794955 10694/582/79738/10575/123016/585/7203/10576/8766/6950/55212/8729/117177/583/22948/378/92482/8195/129880/4218/166379/27241 22 Reovirus R-HSA-180786 Extension of Telomeres 15/2430 30/10654 0.0010057752614936741 0.0029084756479557327 0.0015766082932505076 6118/7015/10856/5111/5426/6119/1736/5985/55135/5984/8607/6117/5981/5424/56655 15 Reovirus R-HSA-2979096 NOTCH2 Activation and Transmission of Signal to the Nucleus 12/2430 22/10654 0.0012158633995784296 0.0035008480643034094 0.0018977178287431023 4192/142678/23385/7316/5664/83464/6233/7311/55851/51107/5663/7314 12 Reovirus R-HSA-9609523 Insertion of tail-anchored proteins into the endoplasmic reticulum membrane 12/2430 22/10654 0.0012158633995784296 0.0035008480643034094 0.0018977178287431023 351/9218/10952/5621/8266/23480/7917/118424/2010/6844/224/6449 12 Reovirus R-HSA-1296041 Activation of G protein gated Potassium channels 13/2430 25/10654 0.0013706801861144127 0.003921260660918319 0.0021256124603780363 2788/54331/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 13 Reovirus R-HSA-1296059 G protein gated Potassium channels 13/2430 25/10654 0.0013706801861144127 0.003921260660918319 0.0021256124603780363 2788/54331/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 13 Reovirus R-HSA-997272 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits 13/2430 25/10654 0.0013706801861144127 0.003921260660918319 0.0021256124603780363 2788/54331/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 13 Reovirus R-HSA-9614085 FOXO-mediated transcription 26/2430 65/10654 0.0013866710025036409 0.0039585308960360345 0.0021458156763889 5105/2290/65018/4802/7532/207/10971/2810/4287/7534/694/114907/1026/84676/1387/4088/2908/10628/6794/2033/3066/3065/4087/56729/23411/7529 26 Reovirus R-HSA-177929 Signaling by EGFR 21/2430 49/10654 0.0014033794467478004 0.003989180725223535 0.0021624301441489063 5295/6464/5290/2060/7316/6714/867/55824/9146/1445/998/30011/6233/2885/7311/1956/3845/3265/5781/5829/7314 21 Reovirus R-HSA-9012852 Signaling by NOTCH3 21/2430 49/10654 0.0014033794467478004 0.003989180725223535 0.0021624301441489063 142678/2648/23462/4904/23385/7316/4854/5664/11060/22938/1387/2033/83464/6233/7311/1956/55851/51107/4851/5663/7314 21 Reovirus R-HSA-9034015 Signaling by NTRK3 (TRKC) 10/2430 17/10654 0.0014620648302022068 0.004147173276327278 0.002248073758362092 5295/6464/5290/3667/6714/2885/581/3845/3265/25920 10 Reovirus R-HSA-350054 Notch-HLH transcription pathway 14/2430 28/10654 0.0014771842784424287 0.004181182618642129 0.002266509329991951 8841/79885/2648/9734/10013/4854/9611/9759/10014/22938/1387/3066/3065/4851 14 Reovirus R-HSA-201681 TCF dependent signaling in response to WNT 73/2430 233/10654 0.0015380451847100299 0.004344246018546723 0.0023549017182163136 5718/9070/5689/8945/5684/7015/1487/5682/1499/5525/1459/5700/5707/5526/207/1454/1452/5690/5717/5929/79577/1460/143471/5706/5705/10197/6657/7534/64750/8452/5528/55366/7316/10213/5709/9978/1457/6934/4609/9861/81847/5715/5519/2932/5701/5688/1387/5687/5685/5683/5708/5692/5686/324/2033/5529/5710/5702/3065/5704/6233/5527/7514/7311/5518/8607/25776/5694/5693/7314/123169/5515/5516 73 Reovirus R-HSA-2122948 Activated NOTCH1 Transmits Signal to the Nucleus 15/2430 31/10654 0.0015415612187641107 0.004344991114491249 0.0023553056151670174 142678/409/23385/7316/5664/408/83737/83464/6233/7311/55851/51107/4851/5663/7314 15 Reovirus R-HSA-5685938 HDR through Single Strand Annealing (SSA) 17/2430 37/10654 0.001571915266516294 0.004421218518033197 0.002396626489447557 6118/5893/5888/5883/7486/10111/545/472/580/11073/641/6119/5985/5984/672/7156/6117 17 Reovirus R-HSA-948021 Transport to the Golgi and subsequent modification 60/2430 185/10654 0.0015761343774978807 0.004423772118355396 0.0023980107291431707 9919/58485/22820/84617/79861/10342/11258/1783/51807/10484/10382/347688/5861/55860/830/7277/10381/7278/112714/1780/9554/2517/1781/8655/1315/1639/832/3998/10282/10121/2804/11316/7846/113457/22870/347733/8729/10376/10972/51143/1314/10540/81027/381/2683/9276/6709/5537/10383/84790/378/6396/375/1453/140735/1075/7280/54732/829/1778 60 Reovirus R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 24/2430 59/10654 0.00159048875513905 0.004454702257580232 0.0024147771456155057 7319/7321/56852/7320/79577/7336/5591/7323/7316/51255/5111/7415/7322/118424/7324/6233/23168/7311/7334/5195/7332/3105/7314/123169 24 Reovirus R-HSA-5693538 Homology Directed Repair 47/2430 138/10654 0.0016052479176434538 0.004486634347221034 0.0024320866931043738 51750/1017/6118/5893/151987/5888/5883/7486/10111/7515/5531/51548/545/472/6613/7336/580/11073/7316/641/5111/5426/7517/9656/6119/7341/5429/5985/165918/142/1111/8900/5984/7329/8924/6233/672/7311/6047/79184/7156/6117/7334/5981/5424/7314/56655 47 Rift_valley_fever_virus R-HSA-909733 Interferon alpha/beta signaling 32/82 69/10654 8.601046656144411e-52 3.681247968829808e-49 2.1185735974082026e-49 3449/3440/3455/3448/10379/9021/3443/3660/3665/3434/3456/3444/3446/3452/6773/6772/3454/7297/8651/3663/5781/5777/3659/3662/4599/3445/3664/3451/3661/3441/5770/3716 32 Rift_valley_fever_virus R-HSA-912694 Regulation of IFNA signaling 22/82 26/10654 2.1194961749639303e-44 4.535721814422811e-42 2.6103268681134726e-42 3449/3440/3455/3448/9021/3443/3456/3444/3446/3452/6773/6772/3454/7297/8651/5781/5777/3445/3451/3441/5770/3716 22 Rift_valley_fever_virus R-HSA-913531 Interferon Signaling 37/82 199/10654 4.816029556345324e-43 6.870868833719328e-41 3.954213740999319e-41 3449/3717/3440/3455/3448/10379/9021/3459/3443/3660/3665/3434/3456/3444/3446/3452/6773/6772/3458/3460/3454/7297/8651/3663/5781/5777/3659/3662/4599/3445/3664/3451/3661/3441/5770/3716/23586 37 Rift_valley_fever_virus R-HSA-933541 TRAF6 mediated IRF7 activation 19/82 29/10654 1.3841602218073581e-34 1.4810514373338732e-32 8.523512944813732e-33 3449/64135/3440/3448/3443/3665/29110/3456/3444/3446/3452/57506/1387/3445/2033/3451/3661/3441/23586 19 Rift_valley_fever_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 22/82 78/10654 1.5151066182896553e-29 1.296931265255945e-27 7.463893656416408e-28 3449/64135/3440/3448/3443/3665/29110/3456/3444/3446/3452/57506/4790/1387/3445/2033/5970/3146/3451/3661/3441/23586 22 Rift_valley_fever_virus R-HSA-449147 Signaling by Interleukins 33/82 461/10654 4.076429726316208e-24 2.9078532047722284e-22 1.673481677119286e-22 3717/3605/7124/3559/3627/3586/2353/9021/3576/29110/282618/3563/4615/53832/163702/6773/6772/6352/3458/7297/8651/3588/5781/3725/5777/4790/3662/3569/5970/6597/3146/3716/1386 33 Rift_valley_fever_virus R-HSA-877300 Interferon gamma signaling 19/82 92/10654 1.1065418937994126e-22 6.7657132935164086e-21 3.893696287955828e-21 3717/10379/9021/3459/3660/3665/6772/3458/3460/8651/3663/5781/5777/3659/3662/3664/3661/5770/3716 19 Rift_valley_fever_virus R-HSA-877312 Regulation of IFNG signaling 11/82 14/10654 1.0001740762921134e-21 5.3509313081628067e-20 3.0794833401625603e-20 3717/9021/3459/6772/3458/3460/8651/5781/5777/5770/3716 11 Rift_valley_fever_virus R-HSA-918233 TRAF3-dependent IRF activation pathway 9/82 14/10654 1.1710657985141937e-16 5.569068464045277e-15 3.2050221854072674e-15 64135/3665/29110/3456/57506/1387/2033/3661/23586 9 Rift_valley_fever_virus R-HSA-8854691 Interleukin-20 family signaling 10/82 25/10654 1.232901595063074e-15 5.2768188268699564e-14 3.0368312973132567e-14 3717/282618/53832/163702/6773/6772/7297/3588/5781/3716 10 Rift_valley_fever_virus R-HSA-168898 Toll-like Receptor Cascades 16/82 155/10654 3.367486646447701e-14 1.3102584406178326e-12 7.540592107835045e-13 54106/7099/2353/3665/29110/4615/7098/8651/5781/3725/51284/4790/5970/3146/3661/1386 16 Rift_valley_fever_virus R-HSA-1059683 Interleukin-6 signaling 7/82 11/10654 3.966941736320256e-13 1.4148758859542246e-11 8.142669879815264e-12 3717/9021/6772/7297/5781/3569/3716 7 Rift_valley_fever_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 13/82 108/10654 1.422736727375339e-12 4.6840870716665e-11 2.695711693974327e-11 3717/3605/7124/3586/2353/9021/3576/6772/7297/8651/3662/3569/3716 13 Rift_valley_fever_virus R-HSA-983231 Factors involved in megakaryocyte development and platelet production 15/82 168/10654 1.971555037183689e-12 6.027325399390136e-11 3.4687509676765665e-11 3449/3717/3440/60/3448/3443/3660/3456/3444/3446/3452/3659/3445/3451/3441 15 Rift_valley_fever_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 13/82 129/10654 1.4317784760385722e-11 4.08534125163006e-10 2.3511309711791294e-10 7099/2353/3665/29110/4615/8651/5781/3725/4790/5970/3146/3661/1386 13 Rift_valley_fever_virus R-HSA-6783783 Interleukin-10 signaling 9/82 47/10654 6.4972933590459e-11 1.7380259735447782e-9 1.000241214484698e-9 7124/3627/3586/3576/6352/7297/3588/3569/3716 9 Rift_valley_fever_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 11/82 93/10654 1.0308911478262882e-10 2.451230062609174e-9 1.410693149657026e-9 54106/7099/2353/3665/4615/3725/51284/4790/5970/3146/1386 11 Rift_valley_fever_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 11/82 93/10654 1.0308911478262882e-10 2.451230062609174e-9 1.410693149657026e-9 54106/7099/2353/3665/4615/3725/51284/4790/5970/3146/1386 11 Rift_valley_fever_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 11/82 97/10654 1.6411163723298118e-10 3.6968305650376817e-9 2.1275414466768754e-9 54106/7099/2353/3665/4615/3725/51284/4790/5970/3146/1386 11 Rift_valley_fever_virus R-HSA-166166 MyD88-independent TLR4 cascade 11/82 99/10654 2.054241650847389e-10 4.186740126488964e-9 2.409486447610472e-9 7099/2353/3665/29110/5781/3725/4790/5970/3146/3661/1386 11 Rift_valley_fever_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 11/82 99/10654 2.054241650847389e-10 4.186740126488964e-9 2.409486447610472e-9 7099/2353/3665/29110/5781/3725/4790/5970/3146/3661/1386 11 Rift_valley_fever_virus R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 8/82 38/10654 3.5245127266933854e-10 6.85677930465804e-9 3.9461051581160396e-9 6599/6601/8289/2033/6598/6605/6597/6602 8 Rift_valley_fever_virus R-HSA-6783589 Interleukin-6 family signaling 7/82 24/10654 3.8392560883289574e-10 7.14435480784693e-9 4.111606062558244e-9 3717/9021/6772/7297/5781/3569/3716 7 Rift_valley_fever_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 9/82 63/10654 1.0219824504919392e-9 1.822535370043958e-8 1.048876725504885e-8 3665/29110/4615/7098/4790/1387/2033/5970/3661 9 Rift_valley_fever_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 10/82 92/10654 1.7978306578646564e-9 3.077886086264292e-8 1.771336311327704e-8 54106/7099/2353/4615/3725/51284/4790/5970/3146/1386 10 Rift_valley_fever_virus R-HSA-3247509 Chromatin modifying enzymes 15/82 274/10654 2.067281370816518e-9 3.2770238026276654e-8 1.8859408996922622e-8 3717/6599/6601/60/8850/8289/4790/1387/2033/5970/6598/6605/6597/6602/1386 15 Rift_valley_fever_virus R-HSA-4839726 Chromatin organization 15/82 274/10654 2.067281370816518e-9 3.2770238026276654e-8 1.8859408996922622e-8 3717/6599/6601/60/8850/8289/4790/1387/2033/5970/6598/6605/6597/6602/1386 15 Rift_valley_fever_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 10/82 94/10654 2.2265379651988964e-9 3.4034223182325986e-8 1.9586837738967736e-8 2353/3665/29110/7098/3725/4790/5970/3146/3661/1386 10 Rift_valley_fever_virus R-HSA-8878171 Transcriptional regulation by RUNX1 14/82 239/10654 3.1706344869210524e-9 4.6794191738007254e-8 2.69302529923603e-8 6599/6601/3559/9021/8850/8289/3458/5781/1387/2033/6598/6605/6597/6602 14 Rift_valley_fever_virus R-HSA-110056 MAPK3 (ERK1) activation 5/82 10/10654 5.837592281384336e-9 8.328298321441653e-8 4.792970504715561e-8 3717/7297/5781/3569/3716 5 Rift_valley_fever_virus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 6/82 21/10654 8.544468143804538e-9 1.1796878598543039e-7 6.789152956367614e-8 29110/4615/7098/4790/5970/3661 6 Rift_valley_fever_virus R-HSA-933542 TRAF6 mediated NF-kB activation 6/82 24/10654 2.0807320759307858e-8 2.6986464499950795e-7 1.5530823150488163e-7 64135/57506/4790/5970/3146/23586 6 Rift_valley_fever_virus R-HSA-982772 Growth hormone receptor signaling 6/82 24/10654 2.0807320759307858e-8 2.6986464499950795e-7 1.5530823150488163e-7 3717/9021/6772/8651/5777/5770 6 Rift_valley_fever_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 9/82 95/10654 4.1606697782638686e-8 5.087904757419817e-7 2.928110460492467e-7 7099/2353/4615/8651/3725/4790/5970/3146/1386 9 Rift_valley_fever_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 9/82 95/10654 4.1606697782638686e-8 5.087904757419817e-7 2.928110460492467e-7 7099/2353/4615/8651/3725/4790/5970/3146/1386 9 Rift_valley_fever_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 9/82 98/10654 5.4696626590215856e-8 6.327069238003349e-7 3.64125480003144e-7 7099/2353/4615/8651/3725/4790/5970/3146/1386 9 Rift_valley_fever_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 9/82 98/10654 5.4696626590215856e-8 6.327069238003349e-7 3.64125480003144e-7 7099/2353/4615/8651/3725/4790/5970/3146/1386 9 Rift_valley_fever_virus R-HSA-3214858 RMTs methylate histone arginines 8/82 79/10654 1.4582484950046085e-7 1.6424483048999274e-6 9.452358665680842e-7 3717/6599/6601/8289/6598/6605/6597/6602 8 Rift_valley_fever_virus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 5/82 18/10654 1.891172149890615e-7 2.0754402055209826e-6 1.1944245157203884e-6 7099/3665/29110/5781/3661 5 Rift_valley_fever_virus R-HSA-112409 RAF-independent MAPK1/3 activation 5/82 23/10654 7.2064015328565e-7 7.710849640156454e-6 4.437626207074793e-6 3717/7297/5781/3569/3716 5 Rift_valley_fever_virus R-HSA-449836 Other interleukin signaling 5/82 24/10654 9.04806688161001e-7 9.00598284960252e-6 5.182980784080153e-6 282618/163702/7297/3588/3716 5 Rift_valley_fever_virus R-HSA-5260271 Diseases of Immune System 5/82 24/10654 9.04806688161001e-7 9.00598284960252e-6 5.182980784080153e-6 7099/4615/7098/4790/5970 5 Rift_valley_fever_virus R-HSA-5602358 Diseases associated with the TLR signaling cascade 5/82 24/10654 9.04806688161001e-7 9.00598284960252e-6 5.182980784080153e-6 7099/4615/7098/4790/5970 5 Rift_valley_fever_virus R-HSA-451927 Interleukin-2 family signaling 6/82 44/10654 9.653836883445194e-7 9.390550422987598e-6 5.404301030445397e-6 3717/3559/3563/6772/5777/3716 6 Rift_valley_fever_virus R-HSA-9020956 Interleukin-27 signaling 4/82 11/10654 1.0324479948863786e-6 9.819727595808222e-6 5.651294287799125e-6 3717/6772/7297/3716 4 Rift_valley_fever_virus R-HSA-8984722 Interleukin-35 Signalling 4/82 12/10654 1.5396087935840674e-6 1.4020267311786827e-5 8.068722456857152e-6 3717/6772/7297/3716 4 Rift_valley_fever_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 4/82 12/10654 1.5396087935840674e-6 1.4020267311786827e-5 8.068722456857152e-6 3665/29110/7098/3661 4 Rift_valley_fever_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 6/82 48/10654 1.637616750458817e-6 1.4602082691591117e-5 8.403559640512352e-6 3717/3559/3563/5781/5777/3716 6 Rift_valley_fever_virus R-HSA-912526 Interleukin receptor SHC signaling 5/82 27/10654 1.6877247213094755e-6 1.4741758790213378e-5 8.483943819257085e-6 3717/3559/3563/5777/3716 5 Rift_valley_fever_virus R-HSA-9018519 Estrogen-dependent gene expression 9/82 150/10654 2.0880657215514354e-6 1.787384257648029e-5 1.0286471133537598e-5 2962/2353/8850/3725/2957/1387/5430/2033/1386 9 Rift_valley_fever_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 7/82 85/10654 3.756232125966592e-6 3.0333346224786822e-5 1.7456967576488234e-5 2353/4615/3725/4790/5970/3146/1386 7 Rift_valley_fever_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 7/82 85/10654 3.756232125966592e-6 3.0333346224786822e-5 1.7456967576488234e-5 2353/4615/3725/4790/5970/3146/1386 7 Rift_valley_fever_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 7/82 85/10654 3.756232125966592e-6 3.0333346224786822e-5 1.7456967576488234e-5 2353/4615/3725/4790/5970/3146/1386 7 Rift_valley_fever_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 4/82 15/10654 4.171509813849197e-6 3.306307778384178e-5 1.902793950176827e-5 54106/3665/4615/51284 4 Rift_valley_fever_virus R-HSA-447115 Interleukin-12 family signaling 6/82 57/10654 4.583003159918029e-6 3.56640973171803e-5 2.05248371181018e-5 3717/3586/6772/3458/7297/3716 6 Rift_valley_fever_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 5/82 34/10654 5.576758694447697e-6 4.262237002185026e-5 2.452935215226995e-5 64135/29110/57506/3661/23586 5 Rift_valley_fever_virus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 4/82 17/10654 7.188584633151958e-6 5.397744250857962e-5 3.106424384409157e-5 4615/7098/4790/5970 4 Rift_valley_fever_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 4/82 21/10654 1.7658244072664128e-5 1.303056631569008e-4 7.499145395650466e-5 4790/1387/2033/5970 4 Rift_valley_fever_virus R-HSA-1169408 ISG15 antiviral mechanism 6/82 72/10654 1.8001841879650526e-5 1.3035496509889878e-4 7.501982743025655e-5 3434/6772/4599/3661/3716/23586 6 Rift_valley_fever_virus R-HSA-1433557 Signaling by SCF-KIT 5/82 43/10654 1.8274060527883004e-5 1.3035496509889878e-4 7.501982743025655e-5 3717/6772/8651/5781/5777 5 Rift_valley_fever_virus R-HSA-167161 HIV Transcription Initiation 5/82 47/10654 2.8427573303816222e-5 1.8159703543333346e-4 1.0450985315150033e-4 2962/2960/2959/2957/5430 5 Rift_valley_fever_virus R-HSA-167162 RNA Polymerase II HIV Promoter Escape 5/82 47/10654 2.8427573303816222e-5 1.8159703543333346e-4 1.0450985315150033e-4 2962/2960/2959/2957/5430 5 Rift_valley_fever_virus R-HSA-73776 RNA Polymerase II Promoter Escape 5/82 47/10654 2.8427573303816222e-5 1.8159703543333346e-4 1.0450985315150033e-4 2962/2960/2959/2957/5430 5 Rift_valley_fever_virus R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 5/82 47/10654 2.8427573303816222e-5 1.8159703543333346e-4 1.0450985315150033e-4 2962/2960/2959/2957/5430 5 Rift_valley_fever_virus R-HSA-75953 RNA Polymerase II Transcription Initiation 5/82 47/10654 2.8427573303816222e-5 1.8159703543333346e-4 1.0450985315150033e-4 2962/2960/2959/2957/5430 5 Rift_valley_fever_virus R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 5/82 47/10654 2.8427573303816222e-5 1.8159703543333346e-4 1.0450985315150033e-4 2962/2960/2959/2957/5430 5 Rift_valley_fever_virus R-HSA-9020591 Interleukin-12 signaling 5/82 47/10654 2.8427573303816222e-5 1.8159703543333346e-4 1.0450985315150033e-4 3717/3586/3458/7297/3716 5 Rift_valley_fever_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 6/82 80/10654 3.297085347988483e-5 2.075224307263339e-4 1.1943002653704413e-4 3434/6772/4599/3661/3716/23586 6 Rift_valley_fever_virus R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 4/82 25/10654 3.6458427438668474e-5 2.2614792672101604e-4 1.3014907735542982e-4 8850/6772/1387/2033 4 Rift_valley_fever_virus R-HSA-450341 Activation of the AP-1 family of transcription factors 3/82 10/10654 5.072370121043982e-5 3.035293603386407e-4 1.7468241593517444e-4 2353/3725/1386 3 Rift_valley_fever_virus R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 3/82 10/10654 5.072370121043982e-5 3.035293603386407e-4 1.7468241593517444e-4 8850/1387/2033 3 Rift_valley_fever_virus R-HSA-8939211 ESR-mediated signaling 9/82 223/10654 5.106101388874329e-5 3.035293603386407e-4 1.7468241593517444e-4 2962/2353/8850/3725/2957/1387/5430/2033/1386 9 Rift_valley_fever_virus R-HSA-2586552 Signaling by Leptin 3/82 11/10654 6.935792116627245e-5 4.066464419063645e-4 2.34026727511287e-4 3717/9021/5781 3 Rift_valley_fever_virus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 3/82 12/10654 9.196402529050195e-5 5.31900038166687e-4 3.0611069584605207e-4 64135/57506/23586 3 Rift_valley_fever_virus R-HSA-446652 Interleukin-1 family signaling 7/82 140/10654 9.735295303669864e-5 5.555608519960937e-4 3.197275931310525e-4 29110/4615/5781/5777/4790/5970/3146 7 Rift_valley_fever_virus R-HSA-1679131 Trafficking and processing of endosomal TLR 3/82 13/10654 1.1888997280385327e-4 6.695382678953842e-4 3.8532207252218374e-4 54106/7098/51284 3 Rift_valley_fever_virus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 5/82 65/10654 1.3737194529194122e-4 7.635739296746862e-4 4.394399890405229e-4 2962/2353/3725/5430/1386 5 Rift_valley_fever_virus R-HSA-8941856 RUNX3 regulates NOTCH signaling 3/82 14/10654 1.5047530013354883e-4 8.256849802199859e-4 4.7518515831647005e-4 8850/1387/2033 3 Rift_valley_fever_virus R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 6/82 110/10654 1.956640320712389e-4 0.0010600532370441803 6.100650700155885e-4 2353/3576/3725/4790/3569/5970 6 Rift_valley_fever_virus R-HSA-448424 Interleukin-17 signaling 5/82 72/10654 2.231175208326598e-4 0.0011936787364547298 6.869671036163474e-4 3605/2353/3725/4790/1386 5 Rift_valley_fever_virus R-HSA-193639 p75NTR signals via NF-kB 3/82 16/10654 2.289408852347855e-4 0.001194959742444978 6.877043279196381e-4 4615/4790/5970 3 Rift_valley_fever_virus R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 3/82 16/10654 2.289408852347855e-4 0.001194959742444978 6.877043279196381e-4 8850/1387/2033 3 Rift_valley_fever_virus R-HSA-167172 Transcription of the HIV genome 5/82 73/10654 2.3808981151079032e-4 0.0012277402328508223 7.065696372038674e-4 2962/2960/2959/2957/5430 5 Rift_valley_fever_virus R-HSA-6807505 RNA polymerase II transcribes snRNA genes 5/82 74/10654 2.53814788484373e-4 0.0012932467794203766 7.442689286383871e-4 2962/2960/2959/2957/5430 5 Rift_valley_fever_virus R-HSA-6788467 IL-6-type cytokine receptor ligand interactions 3/82 17/10654 2.76459235363707e-4 0.0013920535615960775 8.011326448929715e-4 3717/7297/3716 3 Rift_valley_fever_virus R-HSA-5683057 MAPK family signaling cascades 9/82 294/10654 4.114442090011332e-4 0.0020476525750288952 0.0011784326181917403 3717/60/3559/3563/7297/5781/3725/3569/3716 9 Rift_valley_fever_virus R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 3/82 20/10654 4.558186384339963e-4 0.0022030514366274834 0.0012678653127664319 8850/1387/2033 3 Rift_valley_fever_virus R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 5/82 84/10654 4.581111632239393e-4 0.0022030514366274834 0.0012678653127664319 7124/4790/1387/2033/5970 5 Rift_valley_fever_virus R-HSA-674695 RNA Polymerase II Pre-transcription Events 5/82 84/10654 4.581111632239393e-4 0.0022030514366274834 0.0012678653127664319 2962/2960/2959/2957/5430 5 Rift_valley_fever_virus R-HSA-9006931 Signaling by Nuclear Receptors 9/82 299/10654 4.65209308664419e-4 0.002212328712315237 0.001273204423713147 2962/2353/8850/3725/2957/1387/5430/2033/1386 9 Rift_valley_fever_virus R-HSA-9008059 Interleukin-37 signaling 3/82 21/10654 5.28845370827551e-4 0.002469122367912165 0.0014209902461668634 29110/5781/5777 3 Rift_valley_fever_virus R-HSA-9012852 Signaling by NOTCH3 4/82 49/10654 5.30745929551213e-4 0.002469122367912165 0.0014209902461668634 8850/6772/1387/2033 4 Rift_valley_fever_virus R-HSA-2559583 Cellular Senescence 7/82 195/10654 7.370997490122735e-4 0.0033922440062070223 0.0019522506085893833 2353/3576/3456/3725/4790/3569/5970 7 Rift_valley_fever_virus R-HSA-5684996 MAPK1/MAPK3 signaling 8/82 255/10654 7.455680732751478e-4 0.003394714205976205 0.001953672218884486 3717/60/3559/3563/7297/5781/3569/3716 8 Rotavirus_A R-HSA-416476 G alpha (q) signalling events 167/1095 217/10654 2.6859571523224256e-123 3.357446440403032e-120 2.2081395115408573e-120 5295/2788/10316/146/3356/84109/2922/2149/23620/3357/1839/351/4893/8477/84432/5290/54331/4923/10161/1909/2828/1128/3062/5331/1907/59345/148/6375/23566/2358/6863/1131/84539/5578/6846/27334/846/3358/594857/10681/6915/1908/5021/6865/51764/2150/94235/3060/5330/2797/10911/301/5032/2642/2769/3827/2798/56923/5737/338557/2693/3061/55970/57105/1133/29933/5020/7201/3269/4935/887/4829/2767/2792/60675/886/2911/2840/2862/1906/553/5367/257313/5028/8503/2864/5031/8620/2793/3814/10800/6866/5588/23236/7200/2863/94233/56413/2785/2783/624/2641/2796/2784/2829/5029/2782/222545/8525/6288/2867/4828/2776/185/695/1241/2786/680/5332/6654/2885/183/5580/1910/1385/64106/2847/57121/6870/128674/885/4922/9170/5731/2865/1956/5296/5581/10874/347148/2846/3845/84634/147/552/2925/3265/9630/2151/6869/387129/4295/1902/551/129521/8111/9002/2791/2915/2147/5724/10886/2790/2520/2787/2837/623 167 Rotavirus_A R-HSA-2219528 PI3K/AKT Signaling in Cancer 79/1095 101/10654 6.800673905037427e-59 4.250421190648392e-56 2.7954349051759113e-56 5295/5170/1839/685/5290/3667/8823/2309/5291/2065/842/3815/207/2069/8074/7249/930/3082/8817/941/2064/2260/2100/2254/152831/1950/2263/4233/50852/2249/26281/6714/2099/10818/2248/8503/2932/2261/5159/2247/2255/29851/5880/10000/145957/3084/2534/9965/391/5728/2264/2066/27006/942/208/9542/2885/10718/2475/7409/8660/2246/1385/2251/5154/3932/5293/5155/2252/1956/4254/118788/5296/2549/5781/5156/940/5879/4193 79 Rotavirus_A R-HSA-199418 Negative regulation of the PI3K/AKT network 82/1095 110/10654 3.886899215081639e-58 1.6195413396173497e-55 1.0651467673609686e-55 5295/23396/3643/1839/685/5305/5290/3667/8823/5291/2065/3815/207/2069/8074/930/3082/79837/8817/941/2064/8395/2260/2100/2254/152831/1950/2263/4233/50852/2249/26281/6714/2099/10818/2248/8503/2261/5159/2247/2255/29851/5880/10000/145957/3084/2534/9965/391/5728/2264/3630/2066/27006/942/7189/208/9542/2885/10718/8396/7409/8660/2246/2251/5154/3932/5293/5518/5155/2252/1956/4254/118788/5296/8394/2549/5781/5156/940/5879/3556 82 Rotavirus_A R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 67/1095 75/10654 7.41551885741133e-58 2.3173496429410407e-55 1.5240842704311183e-55 5295/1839/685/5290/3667/8823/5291/2065/3815/2069/8074/930/3082/8817/941/2064/2260/2100/2254/152831/1950/2263/4233/50852/2249/26281/6714/2099/10818/2248/8503/2261/5159/2247/2255/29851/5880/145957/3084/2534/9965/391/2264/2066/27006/942/9542/2885/10718/7409/8660/2246/2251/5154/3932/5293/5155/2252/1956/4254/118788/5296/2549/5781/5156/940/5879 67 Rotavirus_A R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 79/1095 103/10654 1.0600122933592865e-57 2.6500307333982163e-055 1.7428833707654796e-55 5295/23396/3643/1839/685/5305/5290/3667/8823/5291/2065/3815/207/2069/8074/930/3082/79837/8817/941/2064/8395/2260/2100/2254/152831/1950/2263/4233/50852/2249/26281/6714/2099/10818/2248/8503/2261/5159/2247/2255/29851/5880/145957/3084/2534/9965/391/2264/3630/2066/27006/942/7189/9542/2885/10718/8396/7409/8660/2246/2251/5154/3932/5293/5518/5155/2252/1956/4254/118788/5296/8394/2549/5781/5156/940/5879/3556 79 Rotavirus_A R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 169/1095 473/10654 6.673860822632904e-53 1.390387671381855e-50 9.14436017978298e-51 5295/5170/4908/5777/627/3643/9402/5800/5590/1839/3918/4893/6464/685/5290/3667/5335/8823/558/5241/5579/5770/4915/5291/1495/5604/1499/2065/5747/4690/526/3815/10006/1848/537/7424/207/7422/5578/2069/2322/7074/8074/284217/5908/3082/3178/8817/51741/10451/23385/2064/382/2260/3912/348/3688/2254/673/152831/1500/1950/5140/9047/6774/2263/5289/4233/10768/2249/6772/26281/6714/2099/5605/10818/2248/1003/8503/2261/867/5159/4067/3717/2566/4909/2321/2247/4914/2255/10000/145957/3320/3084/2534/3690/9965/3728/4803/8471/1445/1111/2264/3630/998/2066/27006/208/6654/9542/30011/2885/7525/1398/10718/7410/5580/2324/2475/7409/8660/2246/1385/3685/5228/5906/2251/9846/5154/3932/3479/5518/5155/1213/3791/387/2252/1956/1211/4254/5296/5581/9564/3845/10076/2549/3265/1399/523/801/1020/5781/30849/8877/23769/3480/22916/11033/2554/5725/11140/4916/5156/5829/5879/9296/6387/2242/5607 169 Rotavirus_A R-HSA-5663202 Diseases of signal transduction 143/1095 377/10654 3.294672123146293e-48 5.883343077046953e-46 3.869381846883091e-46 5295/27044/5170/8805/1839/4893/11052/6464/26127/685/5290/3667/5335/8823/2309/5291/5604/1499/2065/842/3815/10956/207/3674/7094/2069/9530/613/8074/7249/5908/930/3082/7414/8817/941/10013/23385/2064/2260/9208/2100/84447/2254/673/152831/1950/6774/2263/89780/4233/50852/2249/6772/26281/6714/2099/5605/4609/10818/7415/10014/2248/8503/399687/2932/2261/5701/867/5159/7046/3717/4088/2247/2255/29851/5880/10000/145957/3320/3084/2534/3690/9965/391/55294/5728/6400/1445/2264/3066/3065/2066/27006/5894/4087/942/208/6654/9542/2885/10718/2475/7409/56829/8660/2246/1385/7048/51009/8826/27248/5906/2251/9846/5154/3932/5293/5518/5155/2252/1956/11160/4254/118788/5296/7040/3845/2549/3265/369/801/5781/4851/22916/7750/11140/5245/5156/940/1523/5879/4193 143 Rotavirus_A R-HSA-9607240 FLT3 Signaling 118/1095 267/10654 6.989983331962925e-48 1.092184895619207e-45 7.183127608240848e-46 5295/5786/5170/1839/2674/3562/4893/6464/685/5290/1437/3667/8823/5291/5604/2065/3561/5747/3815/1848/3674/7094/7010/1439/2069/2322/2675/8074/5908/3082/7414/3568/8817/2064/4902/1438/2260/8452/2254/2902/673/152831/1950/3560/2676/5140/1852/2263/5289/4233/3055/3718/2668/2249/25780/26281/6714/5605/10818/2248/64096/2261/5701/27040/5159/3567/3558/3717/2247/2255/145957/3084/2534/3690/9965/1445/2264/2066/27006/5894/3563/5979/208/6654/9542/1739/2885/10718/6709/51332/3716/88/8660/2246/8826/5906/2251/9846/5154/5518/5155/9048/2252/1956/4254/5296/3845/2549/5623/3265/3559/369/801/5781/30849/5245/5156/284 118 Rotavirus_A R-HSA-500792 GPCR ligand binding 158/1095 468/10654 1.1970934896660297e-45 1.6626298467583745e-43 1.0934853981627711e-43 2788/10316/146/4544/3356/4543/84109/2922/2149/23620/3357/351/7476/8477/7852/84432/54331/4923/10161/1909/2828/1128/3062/1907/59345/148/6375/23566/2358/6863/1131/1889/84539/6846/27334/846/3358/594857/10681/6915/1908/5021/6865/51764/2150/94235/3060/2797/10911/301/2912/5032/2642/3827/2798/56923/5737/338557/2693/2357/4985/3061/55970/57105/1133/29933/5020/7201/89780/3269/4935/887/4829/186/2792/60675/886/2911/2840/2862/1906/553/7253/5367/257313/5028/2864/1901/5031/8620/2793/3814/10800/6866/5733/7200/2863/94233/56413/2785/2783/624/2641/2796/2784/2829/5029/2782/222545/6288/2867/4828/185/1241/5739/2786/680/183/1910/64106/2847/57121/6870/128674/885/4922/9170/5731/2865/10874/347148/2846/84634/147/552/2925/2151/51384/6869/387129/4295/1902/551/129521/8111/154/9002/2791/2915/2147/5724/7976/10886/2790/2787/2837/6387/623 158 Rotavirus_A R-HSA-76002 Platelet activation, signaling and aggregation 114/1095 262/10654 2.06146167204041e-45 2.5768270900505125e-43 1.694738490382695e-43 5295/2788/5170/2149/5777/5590/351/6464/5290/54331/7018/5579/5770/5291/5747/59345/51097/3937/7424/2770/5336/2316/5175/207/3674/7094/3959/7422/5578/10681/5908/3082/6915/7414/2157/51764/94235/10451/7534/2769/3827/1950/55970/6850/78991/2767/2792/6714/1191/5028/8503/4352/146850/27040/2793/197/4067/23533/5588/81/5265/3309/5880/9948/5294/1/2534/3690/2785/391/2783/2784/1445/2782/87/8525/5345/998/2776/5894/2786/2771/6654/2885/1398/51206/7410/5580/88/7409/5906/5154/3932/3479/5155/387/5296/5581/7040/9564/801/9630/5781/2151/9002/2791/2207/2147/2773/5879/2790/2787/7066/10672 114 Rotavirus_A R-HSA-373076 Class A/1 (Rhodopsin-like receptors) 130/1095 335/10654 4.664271574661733e-45 5.3003086075701516e-43 3.4859292821156113e-43 10316/146/4544/3356/4543/84109/2922/2149/23620/3357/351/8477/7852/84432/4923/10161/1909/2828/1128/3062/1907/148/6375/23566/2358/6863/1131/1889/84539/6846/27334/3358/594857/6915/1908/5021/6865/2150/3060/2797/10911/301/5032/3827/2798/56923/5737/338557/2693/2357/4985/3061/57105/1133/29933/5020/7201/3269/4935/887/4829/186/60675/886/2840/2862/1906/553/7253/5367/257313/5028/2864/1901/5031/8620/3814/10800/6866/5733/7200/2863/94233/56413/624/2796/2829/5029/6288/2867/4828/185/1241/5739/680/183/1910/64106/2847/57121/6870/128674/885/4922/9170/5731/2865/10874/347148/2846/84634/147/552/2925/2151/6869/387129/4295/1902/551/129521/8111/154/9002/2147/5724/10886/2837/6387/623 130 Rotavirus_A R-HSA-5684996 MAPK1/MAPK3 signaling 107/1095 255/10654 8.068903009628314e-41 8.405107301696161e-39 5.5279063601050124e-39 5786/1839/2674/3562/4893/6464/685/1437/3667/8823/5604/2065/3561/5747/3815/1848/3674/7094/7010/1439/2069/2322/2675/8074/5908/3082/7414/3568/8817/2064/4902/1438/2260/8452/2254/2902/673/152831/1950/3560/2676/1852/2263/4233/3718/2668/2249/25780/26281/6714/5605/10818/2248/64096/2261/5701/27040/5159/3567/3558/3717/2247/2255/145957/3084/2534/3690/9965/1445/2264/2066/27006/5894/3563/5979/6654/9542/1739/2885/10718/6709/51332/3716/88/8660/2246/8826/5906/2251/5154/5518/5155/9048/2252/1956/4254/3845/5623/3265/3559/369/801/7297/5781/5245/5156/284 107 Rotavirus_A R-HSA-5673001 RAF/MAP kinase cascade 105/1095 249/10654 2.677738962634702e-40 2.5747490025333675e-38 1.693371765034577e-38 5786/1839/2674/3562/4893/6464/685/1437/3667/8823/5604/2065/3561/5747/3815/1848/3674/7094/7010/1439/2069/2322/2675/8074/5908/3082/7414/3568/8817/2064/4902/1438/2260/8452/2254/2902/673/152831/1950/3560/2676/1852/2263/4233/3718/2668/2249/25780/26281/6714/5605/10818/2248/64096/2261/5701/27040/5159/3567/3558/3717/2247/2255/145957/3084/2534/3690/9965/1445/2264/2066/27006/5894/3563/5979/6654/9542/1739/2885/10718/6709/51332/3716/88/8660/2246/8826/5906/2251/5154/5518/5155/9048/2252/1956/4254/3845/5623/3265/3559/369/801/5245/5156/284 105 Rotavirus_A R-HSA-5683057 MAPK family signaling cascades 111/1095 294/10654 4.000199811311967e-37 3.5716069743856855e-35 2.3489895132591329e-35 5786/1839/2674/3562/4893/6464/685/1437/3667/8823/2309/5604/2065/3561/5747/3815/1848/3674/7094/7010/1439/2069/2322/2675/8074/5908/3082/7414/3568/8817/2064/4902/1438/2260/8452/2254/2902/673/152831/1950/3560/2676/1852/2263/4233/3718/2668/2249/25780/26281/6714/5605/4609/10818/2248/64096/2261/5701/27040/5159/3567/3558/3717/2247/2255/145957/3084/2534/3690/9965/1445/2264/998/2066/27006/5894/3563/5979/6654/9542/1739/2885/10718/6709/51332/3716/88/8660/2246/8826/5906/2251/5154/5518/5155/9048/2252/1956/4254/3845/5623/3265/3559/369/801/7297/5781/5245/5156/5879/284 111 Rotavirus_A R-HSA-9006925 Intracellular signaling by second messengers 111/1095 305/10654 2.1789409951590989e-35 1.8157841626325823e-33 1.1942125734871974e-33 5295/5170/23396/3643/3838/1839/685/5305/5290/3667/5335/8823/2309/5291/2065/842/3815/207/6045/5578/2069/8074/7249/930/3082/79837/8817/941/2064/8395/2260/5573/2100/2254/152831/1950/2263/1457/4233/50852/10768/2249/26281/6714/2099/1108/10818/10014/2248/8503/2932/2261/5701/5159/2247/2255/29851/5880/10000/145957/3084/2534/23512/9965/391/5728/2264/3630/3066/3065/7157/2066/27006/942/7189/208/9542/2885/10718/5580/8396/2475/7409/8660/2246/1385/2251/5154/3932/5293/5518/5155/1386/2252/1956/4254/118788/5296/5581/8394/648/2549/115/801/5781/57521/5156/940/5879/4193/3556 111 Rotavirus_A R-HSA-2428924 IGF1R signaling cascade 44/1095 53/10654 2.6935126989427314e-035 2.104306796049009e-33 1.3839693538646536e-33 5295/5170/4893/6464/5290/3667/8823/5291/2322/8074/8817/2260/2254/152831/5140/2263/5289/2249/26281/10818/2248/2261/2247/2255/9965/8471/2264/27006/208/6654/2885/8660/2246/2251/9846/3479/2252/5296/3845/2549/3265/5781/30849/3480 44 Rotavirus_A R-HSA-1257604 PIP3 activates AKT signaling 102/1095 264/10654 3.726164013438408e-35 2.7398264804694176e-33 1.8019406157866234e-33 5295/5170/23396/3643/1839/685/5305/5290/3667/8823/2309/5291/2065/842/3815/207/6045/2069/8074/7249/930/3082/79837/8817/941/2064/8395/2260/2100/2254/152831/1950/2263/1457/4233/50852/2249/26281/6714/2099/1108/10818/10014/2248/8503/2932/2261/5701/5159/2247/2255/29851/5880/10000/145957/3084/2534/23512/9965/391/5728/2264/3630/3066/3065/7157/2066/27006/942/7189/208/9542/2885/10718/8396/2475/7409/8660/2246/1385/2251/5154/3932/5293/5518/5155/1386/2252/1956/4254/118788/5296/8394/648/2549/5781/57521/5156/940/5879/4193/3556 102 Rotavirus_A R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 44/1095 54/10654 1.3135716358537775e-34 9.122025248984566e-33 5.999411974279534e-33 5295/5170/4893/6464/5290/3667/8823/5291/2322/8074/8817/2260/2254/152831/5140/2263/5289/2249/26281/10818/2248/2261/2247/2255/9965/8471/2264/27006/208/6654/2885/8660/2246/2251/9846/3479/2252/5296/3845/2549/3265/5781/30849/3480 44 Rotavirus_A R-HSA-2428928 IRS-related events triggered by IGF1R 43/1095 52/10654 2.254748375055461e-34 1.4833870888522767e-32 9.756002664367396e-33 5295/5170/4893/5290/3667/8823/5291/2322/8074/8817/2260/2254/152831/5140/2263/5289/2249/26281/10818/2248/2261/2247/2255/9965/8471/2264/27006/208/6654/2885/8660/2246/2251/9846/3479/2252/5296/3845/2549/3265/5781/30849/3480 43 Rotavirus_A R-HSA-74751 Insulin receptor signalling cascade 43/1095 54/10654 4.784382179360976e-33 2.99023886210061e-31 1.9666328853057489e-31 5295/5170/3643/4893/6464/5290/3667/8823/5291/2322/8074/8817/2260/2254/152831/5140/2263/5289/2249/26281/10818/2248/2261/2247/2255/9965/2264/3630/27006/208/6654/2885/8660/2246/2251/9846/2252/5296/3845/2549/3265/5781/30849 43 Rotavirus_A R-HSA-112399 IRS-mediated signalling 40/1095 48/10654 2.6125094067839724e-32 1.5550651230856978e-30 1.0227417777936253e-30 5295/5170/4893/5290/3667/8823/5291/2322/8074/8817/2260/2254/152831/5140/2263/5289/2249/26281/10818/2248/2261/2247/2255/9965/2264/27006/208/6654/2885/8660/2246/2251/9846/2252/5296/3845/2549/3265/5781/30849 40 Rotavirus_A R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 39/1095 48/10654 1.0537372162452847e-30 5.987143274120936e-29 3.93764959754817e-29 5295/5777/3562/3635/6464/5290/1437/5291/3561/1439/3568/1438/7534/3560/3055/6850/3718/8503/867/3567/3558/4067/3717/29760/3636/2534/3563/6654/2885/7525/1398/3716/7409/9846/5293/5296/1399/3559/5781 39 Rotavirus_A R-HSA-9009391 Extra-nuclear estrogen signaling 48/1095 77/10654 1.0069595301182221e-28 5.4726061419468595e-27 3.599246649987787e-27 5295/2788/5170/5590/1839/4893/6464/685/5290/54331/2309/5747/59345/2770/207/2069/10681/51764/94235/2100/1950/55970/2792/6714/2099/8503/2793/10000/3320/2785/2783/2784/2782/2786/2771/208/1385/1956/5296/3845/3265/801/8877/3480/2791/2773/2790/2787 48 Rotavirus_A R-HSA-109704 PI3K Cascade 36/1095 44/10654 1.2457226469271906e-28 6.488138786079119e-27 4.2671464353076136e-27 5295/5170/5290/3667/8823/5291/2322/8074/8817/2260/2254/152831/5140/2263/5289/2249/26281/10818/2248/2261/2247/2255/9965/2264/27006/208/2885/8660/2246/2251/9846/2252/5296/2549/5781/30849 36 Rotavirus_A R-HSA-375276 Peptide ligand-binding receptors 79/1095 201/10654 5.766510496541064e-28 2.8832552482705324e-26 1.896271451704662e-26 10316/84109/2922/2149/23620/351/7852/84432/4923/1909/3062/1907/6375/2358/6863/1889/84539/6846/594857/1908/5021/6865/2150/3060/10911/301/3827/56923/2693/2357/4985/3061/5020/7201/887/4829/186/60675/886/2862/1906/553/5367/257313/8620/3814/6866/7200/624/2829/6288/4828/185/680/183/1910/64106/2847/6870/128674/885/4922/10874/347148/84634/552/2925/2151/6869/387129/4295/551/129521/9002/2147/10886/2837/6387/623 79 Rotavirus_A R-HSA-397795 G-protein beta:gamma signalling 30/1095 32/10654 6.420079125638113e-28 3.086576502710631e-26 2.0299926304143183e-26 2788/5170/54331/5331/59345/207/10681/51764/94235/5330/55970/2792/146850/2793/23533/23236/10000/5294/2785/2783/2784/2782/998/695/2786/208/387/2791/2790/2787 30 Rotavirus_A R-HSA-912526 Interleukin receptor SHC signaling 27/1095 27/10654 1.5678675931589167e-27 7.258646264624615e-26 4.773897038039432e-26 5295/5777/3562/3635/6464/5290/1437/5291/3561/1439/3568/1438/3560/3718/8503/3567/3558/3717/3636/3563/6654/2885/3716/9846/5293/5296/3559 27 Rotavirus_A R-HSA-74752 Signaling by Insulin receptor 47/1095 78/10654 3.3424489069794366e-27 1.49216469061582e-25 9.8137315652291e-26 5295/5170/3643/4893/6464/5290/3667/8823/5291/526/537/2322/8074/8817/2260/2254/152831/5140/2263/5289/2249/26281/10818/2248/2261/2247/2255/9965/2264/3630/27006/208/6654/2885/8660/2246/2251/9846/2252/5296/3845/2549/3265/523/5781/30849/9296 47 Rotavirus_A R-HSA-2424491 DAP12 signaling 28/1095 30/10654 5.589630165423928e-26 2.409323347165486e-24 1.5845739234831535e-24 5295/9402/4893/6464/5290/5335/7305/5291/3937/5336/3824/10451/54209/567/6850/27040/2534/3822/695/6654/2885/7410/3133/3932/5296/3845/3265/5879 28 Rotavirus_A R-HSA-1226099 Signaling by FGFR in disease 41/1095 63/10654 8.700273980321282e-26 3.6251141584672006e-24 2.3841803433792705e-24 5295/8805/4893/11052/26127/5290/5335/8823/9530/613/8074/8817/2260/9208/2254/6774/2263/2249/6772/26281/10818/2248/399687/2261/2247/2255/2264/27006/6654/2885/2246/2251/9846/2252/11160/3845/2549/3265/22916/7750/1523 41 Rotavirus_A R-HSA-392451 G beta:gamma signalling through PI3Kgamma 25/1095 25/10654 1.5484309860346983e-025 6.243673330785074e-24 4.1063653653415945e-24 2788/5170/54331/59345/207/10681/51764/94235/55970/2792/146850/2793/23533/10000/5294/2785/2783/2784/2782/2786/208/387/2791/2790/2787 25 Rotavirus_A R-HSA-5655302 Signaling by FGFR1 in disease 31/1095 38/10654 9.829934060014419e-25 3.8398179921931327e-23 2.5253876647602837e-23 5295/8805/4893/11052/26127/5290/5335/9530/613/8074/2260/9208/2254/6774/2249/6772/26281/10818/399687/2247/6654/2885/2246/2251/9846/11160/3845/2549/3265/7750/1523 31 Rotavirus_A R-HSA-392518 Signal amplification 28/1095 32/10654 3.768291273999824e-24 1.4273830583332666e-22 9.387672998385528e-23 2788/54331/59345/2770/10681/6915/51764/94235/2769/55970/2767/2792/6714/5028/2793/2785/2783/2784/2782/2776/2786/2771/9630/2791/2773/2790/2787/10672 28 Rotavirus_A R-HSA-114604 GPVI-mediated activation cascade 29/1095 35/10654 1.3925675223342696e-23 5.119733537993638e-22 3.3671679100404476e-22 5295/5170/5777/5590/5290/5291/3937/5336/10451/6850/8503/146850/27040/4067/23533/5880/5294/2534/391/998/51206/7410/7409/3932/387/5296/5781/2207/5879 29 Rotavirus_A R-HSA-428930 Thromboxane signalling through TP receptor 23/1095 23/10654 1.5241053234113618e-23 5.443233297897721e-22 3.579928594238417e-22 2788/54331/59345/10681/6915/51764/94235/2769/55970/2767/2792/2793/2785/2783/2784/2782/2776/2786/9630/2791/2790/2787/10672 23 Rotavirus_A R-HSA-451927 Interleukin-2 family signaling 32/1095 44/10654 9.87588728988741e-23 3.429127531210907e-21 2.2552830331584993e-21 5295/5777/3562/3635/6464/5290/1437/5291/3561/1439/3568/1438/3560/84868/6774/6850/3718/6772/8503/3567/3558/3717/3636/3563/6654/2885/3716/9846/3932/5293/5296/3559 32 Rotavirus_A R-HSA-1227986 Signaling by ERBB2 34/1095 50/10654 1.5333064957742442e-22 5.1800895127508246e-21 3.406863081649174e-21 5295/1839/4893/6464/685/5290/5335/2065/207/5578/2069/2064/1950/6714/10000/145957/3320/3084/2534/2066/208/6654/9542/2885/7525/10718/5580/387/1956/5581/3845/2549/3265/11140 34 Rotavirus_A R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 27/1095 32/10654 1.8966869184376763e-22 6.239101705387093e-21 4.103358679500901e-21 2788/2149/54331/59345/10681/51764/94235/2769/55970/2767/2792/6714/2793/2785/2783/2784/2782/2776/2786/9630/2151/9002/2791/2147/2790/2787/10672 27 Rotavirus_A R-HSA-5654696 Downstream signaling of activated FGFR2 26/1095 30/10654 2.842190638074186e-22 9.109585378442903e-21 5.9912304678432906e-21 5295/4893/6464/5290/5335/8823/8074/8817/2254/2263/2249/26281/10818/2248/2247/2255/27006/6654/2885/2246/2251/2252/3845/2549/3265/5781 26 Rotavirus_A R-HSA-388841 Costimulation by the CD28 family 40/1095 70/10654 4.0585508709607623e-22 1.2682971471752382e-20 8.341390079527253e-21 5295/3120/5170/5777/9402/5290/3117/3119/207/3123/941/919/3115/3122/920/3113/6714/8503/4067/915/917/29851/10000/2534/1445/916/998/942/208/2885/7525/2475/7409/3932/5518/5296/3127/5781/940/5879 40 Rotavirus_A R-HSA-194138 Signaling by VEGF 50/1095 107/10654 4.27362442777511e-22 1.3029342767607042e-20 8.569193011790401e-21 5295/5170/5590/4893/5290/5335/558/5579/5291/1495/1499/5747/4690/10006/7424/207/7422/5578/10451/1500/9047/10768/6714/1003/2321/10000/3320/2534/3690/3728/998/208/1398/7410/5580/2324/2475/7409/3685/5228/3791/387/5296/9564/3845/3265/801/8877/5829/5879 50 Rotavirus_A R-HSA-5654716 Downstream signaling of activated FGFR4 24/1095 27/10654 3.313115365143188e-21 9.860462396259488e-20 6.485070426508347e-20 5295/4893/6464/5290/5335/8823/8074/8817/2254/152831/2249/26281/10818/2247/9965/2264/6654/2885/2246/2251/3845/2549/3265/5781 24 Rotavirus_A R-HSA-418592 ADP signalling through P2Y purinoceptor 1 23/1095 25/10654 3.7313554390816414e-21 1.0600441588300118e-19 6.971743057231488e-20 2788/54331/59345/10681/51764/94235/2769/55970/2767/2792/6714/5028/2793/2785/2783/2784/2782/2776/2786/9630/2791/2790/2787 23 Rotavirus_A R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 23/1095 25/10654 3.7313554390816414e-21 1.0600441588300118e-19 6.971743057231488e-20 3135/3107/10484/10802/6890/821/811/6892/6891/22872/567/3106/10134/3309/2923/9632/9871/3133/51128/3134/6396/3105/10427 23 Rotavirus_A R-HSA-418217 G beta:gamma signalling through PLC beta 20/1095 20/10654 1.4790060489195004e-20 4.1083501358875013e-19 2.7019970156868537e-19 2788/54331/5331/59345/10681/51764/94235/5330/55970/2792/2793/23236/2785/2783/2784/2782/2786/2791/2790/2787 20 Rotavirus_A R-HSA-1433557 Signaling by SCF-KIT 30/1095 43/10654 1.5411954548250272e-20 4.188031127241922e-19 2.7544019455797398e-019 5295/5777/9402/4893/5290/3815/5578/6774/6772/6714/8503/867/4067/3717/2534/1111/6654/2885/7525/7409/9846/3932/4254/5296/3845/10076/3265/5781/5879/2242 30 Rotavirus_A R-HSA-4420097 VEGFA-VEGFR2 Pathway 46/1095 99/10654 2.6690269016589618e-20 7.098475802284472e-19 4.66855545396562e-19 5295/5170/5590/4893/5290/5335/558/5579/5291/1495/1499/5747/4690/10006/207/7422/5578/10451/1500/9047/10768/6714/1003/10000/3320/2534/3690/3728/998/208/1398/7410/5580/2475/7409/3685/3791/387/5296/9564/3845/3265/801/8877/5829/5879 46 Rotavirus_A R-HSA-1250196 SHC1 events in ERBB2 signaling 21/1095 22/10654 2.9721683236809754e-20 7.74002167625254e-19 5.090490045602724e-19 1839/4893/6464/685/2065/5578/2069/2064/1950/145957/3084/2066/6654/9542/2885/10718/5580/1956/5581/3845/3265 21 Rotavirus_A R-HSA-500657 Presynaptic function of Kainate receptors 20/1095 21/10654 2.806884772960722e-19 7.160420339185516e-18 4.7092953978138e-18 2788/54331/5331/59345/10681/51764/94235/5330/55970/2792/2793/23236/2785/2783/2784/2782/2786/2791/2790/2787 20 Rotavirus_A R-HSA-5654743 Signaling by FGFR4 28/1095 41/10654 7.376819603774106e-19 1.8442049009435263e-17 1.2129044443258058e-17 5295/4893/6464/5290/5335/8823/8074/8817/2254/673/152831/2249/26281/6714/10818/867/2247/9965/2264/6654/2885/2246/2251/5518/3845/2549/3265/5781 28 Rotavirus_A R-HSA-8964315 G beta:gamma signalling through BTK 18/1095 18/10654 1.4436363155660385e-18 3.538324302857938e-17 2.3271000257111998e-17 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/695/2786/2791/2790/2787 18 Rotavirus_A R-HSA-449147 Signaling by Interleukins 111/1095 461/10654 1.6967260330070631e-18 4.0786683485746713e-17 2.6824757728310047e-17 5295/10148/5777/3562/351/3635/6464/3592/5290/3566/1437/3667/4790/2309/5291/5604/3561/7184/1848/356/3593/5803/207/5292/7422/3553/1439/8878/821/5908/3082/3568/941/3383/301/11009/1438/7534/3313/3688/2357/1436/3565/4985/3560/84868/6774/920/5970/4792/3055/6850/3718/6772/4609/149233/8503/7132/1901/5701/867/79923/3567/3558/4067/3717/29760/4088/3636/2247/3320/4843/2534/9466/3458/6288/998/7157/942/3563/7189/6654/2885/7525/1398/3716/7409/8660/1385/604/3594/53832/9846/3932/5293/5518/1386/5296/7040/51561/375/1399/3559/246778/7297/5781/5724/3554/5034/3598/3556 111 Rotavirus_A R-HSA-1839124 FGFR1 mutant receptor activation 24/1095 31/10654 1.9831314836885223e-18 4.5905821381678755e-17 3.0191533893971465e-17 5295/8805/11052/26127/5290/9530/613/8074/2260/9208/2254/6774/2249/6772/26281/399687/2247/2885/2246/2251/9846/11160/7750/1523 24 Rotavirus_A R-HSA-5654687 Downstream signaling of activated FGFR1 24/1095 31/10654 1.9831314836885223e-18 4.5905821381678755e-17 3.0191533893971465e-17 5295/4893/6464/5290/5335/8074/2260/2254/2249/26281/10818/2248/2247/2255/27006/6654/2885/2246/2251/3845/2549/3265/5781/23769 24 Rotavirus_A R-HSA-392170 ADP signalling through P2Y purinoceptor 12 20/1095 22/10654 2.790356417888703e-18 6.341719131565235e-17 4.170848540423115e-17 2788/54331/59345/2770/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2771/2791/2773/2790/2787 20 Rotavirus_A R-HSA-2172127 DAP12 interactions 28/1095 43/10654 5.174208907988459e-18 1.1549573455331383e-16 7.595972099885315e-17 5295/9402/4893/6464/5290/5335/7305/5291/3937/5336/3824/10451/54209/567/6850/27040/2534/3822/695/6654/2885/7410/3133/3932/5296/3845/3265/5879 28 Rotavirus_A R-HSA-5654700 FRS-mediated FGFR2 signaling 21/1095 25/10654 1.2609127436214876e-17 2.6714253042828124e-16 1.7569542422272646e-16 4893/8823/8074/8817/2254/2263/2249/26281/10818/2248/2247/2255/27006/6654/2885/2246/2251/2252/3845/3265/5781 21 Rotavirus_A R-HSA-5654708 Downstream signaling of activated FGFR3 21/1095 25/10654 1.2609127436214876e-17 2.6714253042828124e-16 1.7569542422272646e-16 5295/4893/6464/5290/5335/8823/8074/8817/2254/2249/26281/10818/2261/2247/6654/2885/2246/3845/2549/3265/5781 21 Rotavirus_A R-HSA-9006115 Signaling by NTRK2 (TRKB) 21/1095 25/10654 1.2609127436214876e-17 2.6714253042828124e-16 1.7569542422272646e-16 5295/4908/627/4893/6464/5290/5335/4915/7074/6714/10818/4909/2534/6654/2885/3845/2549/3265/1020/5781/5879 21 Rotavirus_A R-HSA-5654695 PI-3K cascade:FGFR2 20/1095 23/10654 1.9333738759917655e-17 3.9618317130978805e-16 2.6056341624669005e-16 5295/5290/8823/8074/8817/2254/2263/2249/26281/10818/2248/2247/2255/27006/2885/2246/2251/2252/2549/5781 20 Rotavirus_A R-HSA-5654699 SHC-mediated cascade:FGFR2 20/1095 23/10654 1.9333738759917655e-17 3.9618317130978805e-16 2.6056341624669005e-16 4893/6464/8823/8074/8817/2254/2263/2249/26281/2248/2247/2255/27006/6654/2885/2246/2251/2252/3845/3265 20 Rotavirus_A R-HSA-392851 Prostacyclin signalling through prostacyclin receptor 18/1095 19/10654 2.47978062787969e-17 4.999557717499375e-16 3.288130170414326e-16 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/5739/2786/2791/2790/2787 18 Rotavirus_A R-HSA-166520 Signaling by NTRKs 43/1095 101/10654 2.743811588928915e-17 5.444070612954197e-16 3.580479283130297e-16 5295/4908/627/5800/4893/6464/5290/3667/5335/4915/5291/5604/1848/7074/673/6774/6714/5605/10818/4909/4914/2534/4803/6654/2885/1398/8660/1385/5906/5518/1213/387/1211/5296/3845/2549/3265/1399/1020/5781/4916/5879/5607 43 Rotavirus_A R-HSA-422356 Regulation of insulin secretion 37/1095 78/10654 5.935272483694202e-17 1.1592329069715237e-15 7.624091792376928e-16 2788/54331/5331/59345/2770/1131/5578/10681/51764/94235/5330/2769/5573/55970/2767/10768/2792/2864/2793/23236/2785/2783/2641/2784/2782/3630/2776/2786/2771/8826/5906/9630/2181/2791/6513/2790/2787 37 Rotavirus_A R-HSA-190236 Signaling by FGFR 39/1095 87/10654 9.760749005580963e-17 1.8770671164578773e-15 1.2345174045925075e-15 5295/4893/6464/5290/5335/8823/8074/3178/8817/2260/2254/673/152831/2263/2249/26281/6714/10818/2248/2261/867/2247/2255/9965/2264/27006/6654/2885/2246/2251/5518/2252/3845/2549/3265/5781/23769/22916/5725 39 Rotavirus_A R-HSA-186763 Downstream signal transduction 22/1095 29/10654 1.1584246023476153e-16 2.193985989294726e-15 1.4429499432751e-15 5295/4893/5290/5335/5291/4690/6774/6772/6714/5159/6654/2885/1398/5154/5155/5296/9564/3845/3265/1399/5781/5156 22 Rotavirus_A R-HSA-5654736 Signaling by FGFR1 29/1095 50/10654 1.2513664871952547e-16 2.3346389686478634e-15 1.5354551869591424e-15 5295/4893/6464/5290/5335/8074/8817/2260/2254/673/2249/26281/6714/10818/2248/867/2247/2255/27006/6654/2885/2246/2251/5518/3845/2549/3265/5781/23769 29 Rotavirus_A R-HSA-1963640 GRB2 events in ERBB2 signaling 16/1095 16/10654 1.4044191354302755e-16 2.507891313268349e-15 1.6494005184526997e-15 1839/4893/685/2069/2064/1950/145957/3084/2066/6654/9542/2885/10718/1956/3845/3265 16 Rotavirus_A R-HSA-1963642 PI3K events in ERBB2 signaling 16/1095 16/10654 1.4044191354302755e-16 2.507891313268349e-15 1.6494005184526997e-15 5295/1839/685/5290/2065/2069/2064/1950/145957/3084/2066/9542/2885/10718/1956/2549 16 Rotavirus_A R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 16/1095 16/10654 1.4044191354302755e-16 2.507891313268349e-15 1.6494005184526997e-15 5295/5170/6464/5290/2205/5291/2206/6850/7462/4067/2534/6654/2885/9846/5296/2207 16 Rotavirus_A R-HSA-5654712 FRS-mediated FGFR4 signaling 19/1095 22/10654 1.6625619383466667e-16 2.8468526341552515e-15 1.872330027179159e-15 4893/8823/8074/8817/2254/152831/2249/26281/10818/2247/9965/2264/6654/2885/2246/2251/3845/3265/5781 19 Rotavirus_A R-HSA-5655332 Signaling by FGFR3 in disease 19/1095 22/10654 1.6625619383466667e-16 2.8468526341552515e-15 1.872330027179159e-15 5295/4893/5290/5335/8823/8074/8817/2254/2249/26281/10818/2261/2247/6654/2885/2246/3845/2549/3265 19 Rotavirus_A R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 19/1095 22/10654 1.6625619383466667e-16 2.8468526341552515e-15 1.872330027179159e-15 5295/4893/5290/5335/8823/8074/8817/2254/2249/26281/10818/2261/2247/6654/2885/2246/3845/2549/3265 19 Rotavirus_A R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 23/1095 32/10654 1.7134160640342972e-16 2.894283891949826e-15 1.9035248165160543e-15 5295/5777/4690/5336/930/6850/10768/4067/29760/2534/695/974/6654/30011/2885/7409/5293/118788/27071/801/973/933/6786 23 Rotavirus_A R-HSA-8853659 RET signaling 26/1095 41/10654 2.1465275579860646e-16 3.577545929976775e-15 2.3528954705784094e-15 5295/2674/6464/5290/5335/5291/5578/2675/4902/2676/2668/6714/10818/8503/64096/5979/6654/2885/8660/9846/5293/9048/5296/2549/5623/5781 26 Rotavirus_A R-HSA-5654719 SHC-mediated cascade:FGFR4 18/1095 20/10654 2.24194325962043e-16 3.592857787853253e-15 2.3629658377375925e-15 4893/6464/8823/8074/8817/2254/152831/2249/26281/2247/9965/2264/6654/2885/2246/2251/3845/3265 18 Rotavirus_A R-HSA-5654720 PI-3K cascade:FGFR4 18/1095 20/10654 2.24194325962043e-16 3.592857787853253e-15 2.3629658377375925e-15 5295/5290/8823/8074/8817/2254/152831/2249/26281/10818/2247/9965/2264/2885/2246/2251/2549/5781 18 Rotavirus_A R-HSA-8964616 G beta:gamma signalling through CDC42 18/1095 20/10654 2.24194325962043e-16 3.592857787853253e-15 2.3629658377375925e-15 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/998/2786/2791/2790/2787 18 Rotavirus_A R-HSA-9006335 Signaling by Erythropoietin 20/1095 25/10654 4.737598058906125e-16 7.496199460294501e-15 4.930132023991584e-15 5295/4893/6464/5290/5335/5291/5336/4067/23533/3717/5294/6654/2885/7409/8660/5293/3845/2549/3265/1399 20 Rotavirus_A R-HSA-5654741 Signaling by FGFR3 25/1095 40/10654 1.3537560350635075e-15 2.108967815865336e-14 1.3870348330028022e-14 5295/4893/6464/5290/5335/8823/8074/8817/2254/673/2249/26281/6714/10818/2261/867/2247/6654/2885/2246/5518/3845/2549/3265/5781 25 Rotavirus_A R-HSA-5637810 Constitutive Signaling by EGFRvIII 15/1095 15/10654 1.3834828872076604e-15 2.108967815865336e-14 1.3870348330028022e-14 5295/4893/6464/5290/5335/1950/867/3320/6654/2885/1956/3845/2549/3265/11140 15 Rotavirus_A R-HSA-5637812 Signaling by EGFRvIII in Cancer 15/1095 15/10654 1.3834828872076604e-15 2.108967815865336e-14 1.3870348330028022e-14 5295/4893/6464/5290/5335/1950/867/3320/6654/2885/1956/3845/2549/3265/11140 15 Rotavirus_A R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 37/1095 86/10654 3.0855412252361603e-15 4.646899435596627e-14 3.05619238669555e-14 5295/5290/23646/5335/5291/2214/5747/4690/10006/5336/4627/2268/2209/10451/919/3055/6850/10768/4641/6714/4067/917/3320/2534/998/695/2885/7525/1398/7410/5580/10097/7409/5296/5581/2212/5879 37 Rotavirus_A R-HSA-163685 Integration of energy metabolism 42/1095 108/10654 3.183595747045504e-15 4.737493671198667e-14 3.115774785015713e-14 2788/5563/54331/5331/59345/2770/1131/5578/10681/51764/94235/5330/2642/2769/5573/55970/2767/10768/2792/2864/2793/23236/6794/2785/2783/2641/2784/2782/3630/2776/2786/2771/8826/5906/5518/115/9630/2181/2791/6513/2790/2787 42 Rotavirus_A R-HSA-451326 Activation of kainate receptors upon glutamate binding 22/1095 32/10654 3.532127311991146e-15 5.194304870575214e-14 3.416212298037257e-14 2788/54331/5331/59345/10681/51764/94235/5330/55970/2792/2793/23236/2785/2783/2784/2782/2786/1739/801/2791/2790/2787 22 Rotavirus_A R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 25/1095 42/10654 6.9934050980820814e-15 1.0164832991398374e-13 6.68525016107969e-14 2788/54331/59345/2770/10575/10681/51764/94235/7203/908/55970/1457/2792/2793/2785/2783/2784/2782/5082/2786/2771/2791/2773/2790/2787 25 Rotavirus_A R-HSA-389356 CD28 co-stimulation 22/1095 33/10654 9.574707372743794e-15 1.375676346658591e-13 9.047606119918819e-14 5295/5170/9402/5290/207/941/6714/8503/4067/10000/2534/998/942/208/2885/7525/2475/7409/3932/5296/940/5879 22 Rotavirus_A R-HSA-1250347 SHC1 events in ERBB4 signaling 14/1095 14/10654 1.3617259870388057e-14 1.934269867952849e-13 1.2721387510494108e-13 1839/4893/6464/685/2069/145957/3084/2066/6654/9542/2885/10718/3845/3265 14 Rotavirus_A R-HSA-5655253 Signaling by FGFR2 in disease 25/1095 43/10654 1.5091517104465574e-14 2.119595098941794e-13 1.3940242292829824e-13 5295/4893/5290/5335/8823/8074/8817/2254/2263/2249/26281/10818/2248/2247/2255/27006/6654/2885/2246/2251/2252/3845/2549/3265/22916 25 Rotavirus_A R-HSA-5654738 Signaling by FGFR2 33/1095 73/10654 1.696969154398913e-14 2.3569016033318233e-13 1.5500969702754984e-13 5295/4893/6464/5290/5335/8823/8074/3178/8817/2254/673/2263/2249/26281/6714/10818/2248/867/2247/2255/27006/6654/2885/2246/2251/5518/2252/3845/2549/3265/5781/22916/5725 33 Rotavirus_A R-HSA-202040 G-protein activation 20/1095 28/10654 2.046219445763124e-14 2.810740996927368e-13 1.8485799735581265e-13 2788/54331/59345/2770/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2771/2791/2773/2790/2787 20 Rotavirus_A R-HSA-1236394 Signaling by ERBB4 29/1095 58/10654 2.4728867715160485e-14 3.3599005047772396e-13 2.209753510931389e-13 5295/1839/4893/6464/685/5290/5241/2065/2069/51741/23385/348/1950/6714/2099/2566/145957/3084/2066/6654/9542/2885/10718/1956/3845/3265/11033/2554/6387 29 Rotavirus_A R-HSA-5654693 FRS-mediated FGFR1 signaling 18/1095 23/10654 2.934509669715451e-14 3.9442334270368964e-13 2.5940600475922663e-13 4893/8074/2260/2254/2249/26281/10818/2248/2247/2255/27006/6654/2885/2246/2251/3845/3265/5781 18 Rotavirus_A R-HSA-418597 G alpha (z) signalling events 26/1095 48/10654 4.546058458755798e-14 6.045290503664624e-13 3.975892112304903e-13 2788/54331/5579/59345/2770/5578/10681/51764/94235/55970/2792/2793/5588/2785/2783/2784/2782/2786/2771/5580/5581/115/2791/2773/2790/2787 26 Rotavirus_A R-HSA-5654688 SHC-mediated cascade:FGFR1 17/1095 21/10654 5.70179947194738e-14 7.424218062431485e-13 4.882790995165466e-13 4893/6464/8074/2260/2254/2249/26281/2248/2247/2255/27006/6654/2885/2246/2251/3845/3265 17 Rotavirus_A R-HSA-5654689 PI-3K cascade:FGFR1 17/1095 21/10654 5.70179947194738e-14 7.424218062431485e-13 4.882790995165466e-13 5295/5290/8074/2260/2254/2249/26281/10818/2248/2247/2255/27006/2885/2246/2251/2549/5781 17 Rotavirus_A R-HSA-202433 Generation of second messenger molecules 21/1095 33/10654 1.5730284950978399e-13 2.0064138968084694e-12 1.3195867397115071e-12 3120/9402/5335/4690/3117/3119/3937/3123/919/3115/3122/920/3113/27040/915/917/916/7535/3702/3932/3127 21 Rotavirus_A R-HSA-2871809 FCERI mediated Ca+2 mobilization 21/1095 33/10654 1.5730284950978399e-13 2.0064138968084694e-12 1.3195867397115071e-12 9402/6464/2205/5335/3937/5336/10451/2206/6850/10768/27040/4067/695/6654/2885/7410/7409/3702/801/2207/7294 21 Rotavirus_A R-HSA-912631 Regulation of signaling by CBL 17/1095 22/10654 2.268899645654854e-13 2.86477227986724e-12 1.8841154952221596e-12 5295/5290/5291/3055/6850/8503/867/4067/29760/2534/2885/7525/1398/7409/5293/5296/1399 17 Rotavirus_A R-HSA-1643713 Signaling by EGFR in Cancer 18/1095 25/10654 3.4272758610243894e-13 4.284094826280487e-12 2.8175815236421562e-12 5295/1839/4893/6464/685/5290/5335/2069/1950/867/3320/6654/2885/1956/3845/2549/3265/11140 18 Rotavirus_A R-HSA-5654727 Negative regulation of FGFR2 signaling 21/1095 34/10654 3.718094658115145e-13 4.601602299647457e-12 3.0264011755997172e-12 8823/8074/8817/2254/673/2263/2249/26281/6714/10818/2248/867/2247/2255/27006/2885/2246/2251/5518/2252/5781 21 Rotavirus_A R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 19/1095 28/10654 4.0690699913734055e-13 4.986605381585056e-12 3.279611623594045e-12 2788/54331/59345/2770/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2771/2791/2790/2787 19 Rotavirus_A R-HSA-5654706 FRS-mediated FGFR3 signaling 16/1095 20/10654 4.555900092330526e-13 5.529004966420542e-12 3.6363392663363734e-12 4893/8823/8074/8817/2254/2249/26281/10818/2261/2247/6654/2885/2246/3845/3265/5781 16 Rotavirus_A R-HSA-389948 PD-1 signaling 17/1095 23/10654 7.866004235257536e-13 9.454332013530693e-12 6.217964886372607e-12 3120/5777/3117/3119/3123/919/3115/3122/920/3113/915/917/1445/916/3932/3127/5781 17 Rotavirus_A R-HSA-5654221 Phospholipase C-mediated cascade; FGFR2 15/1095 18/10654 8.363950701044817e-13 9.770970445145815e-12 6.4262129832916904e-12 5335/8823/8074/8817/2254/2263/2249/26281/2248/2247/2255/27006/2246/2251/2252 15 Rotavirus_A R-HSA-5654704 SHC-mediated cascade:FGFR3 15/1095 18/10654 8.363950701044817e-13 9.770970445145815e-12 6.4262129832916904e-12 4893/6464/8823/8074/8817/2254/2249/26281/2261/2247/6654/2885/2246/3845/3265 15 Rotavirus_A R-HSA-5654710 PI-3K cascade:FGFR3 15/1095 18/10654 8.363950701044817e-13 9.770970445145815e-12 6.4262129832916904e-12 5295/5290/8823/8074/8817/2254/2249/26281/10818/2261/2247/2885/2246/2549/5781 15 Rotavirus_A R-HSA-2871796 FCERI mediated MAPK activation 20/1095 32/10654 9.921886009580886e-13 1.1483664362940841e-11 7.552624730489934e-12 9402/4893/6464/2205/5335/3937/5336/10451/2206/6850/27040/4067/6654/2885/7410/7409/3845/3265/2207/5879 20 Rotavirus_A R-HSA-8939211 ESR-mediated signaling 60/1095 223/10654 1.1475349181874969e-12 1.315980410765478e-11 8.654995375223902e-12 5295/2788/5170/3838/5590/1839/4893/6464/685/5290/54331/5241/2309/5747/59345/2770/207/2069/10681/51764/94235/2100/1950/55970/1105/1655/6667/2792/6714/2099/4609/8503/2793/10000/3320/8243/2785/2783/2784/2782/3065/2066/2786/2771/208/1385/1025/1386/1956/5296/3845/3265/801/8877/3480/2791/2773/2790/2787/6387 60 Rotavirus_A R-HSA-2029481 FCGR activation 12/1095 12/10654 1.3159509621833853e-12 1.481926759215524e-11 9.746398306924837e-12 2214/2268/2209/919/3055/6850/6714/4067/917/2534/7525/2212 12 Rotavirus_A R-HSA-210990 PECAM1 interactions 12/1095 12/10654 1.3159509621833853e-12 1.481926759215524e-11 9.746398306924837e-12 5777/3635/5335/5175/6714/4067/2534/3690/7525/3685/3932/5781 12 Rotavirus_A R-HSA-8848021 Signaling by PTK6 26/1095 54/10654 1.6931411130204483e-12 1.8729437090934163e-11 1.2318055046753333e-11 1839/4893/685/5770/2065/207/2069/27043/2064/1950/6774/867/2908/145957/3084/2066/9542/1398/10718/387/1956/9564/3845/3265/5829/5879 26 Rotavirus_A R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 26/1095 54/10654 1.6931411130204483e-12 1.8729437090934163e-11 1.2318055046753333e-11 1839/4893/685/5770/2065/207/2069/27043/2064/1950/6774/867/2908/145957/3084/2066/9542/1398/10718/387/1956/9564/3845/3265/5829/5879 26 Rotavirus_A R-HSA-418346 Platelet homeostasis 34/1095 88/10654 1.7531249265479452e-12 1.9222861036709926e-11 1.2642572184985646e-11 2788/5777/54331/59345/5175/487/2268/10681/51764/94235/338/488/55970/2792/5026/2793/493/4843/490/2785/2783/2784/2782/492/5739/2786/5518/801/5781/2791/22953/2790/6786/2787 34 Rotavirus_A R-HSA-187037 Signaling by NTRK1 (TRKA) 32/1095 80/10654 2.606678537660167e-12 2.833346236587138e-11 1.8634470827575197e-11 5295/4893/6464/5290/3667/5335/4915/5291/5604/1848/673/6774/6714/5605/10818/4914/4803/6654/2885/1398/8660/1385/5906/5518/1213/387/1211/5296/3845/3265/1399/5607 32 Rotavirus_A R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 15/1095 19/10654 3.5951565294830126e-12 3.8084285269947166e-11 2.5047433091224203e-11 5295/4893/6464/5290/5335/1950/867/3320/6654/2885/1956/3845/2549/3265/11140 15 Rotavirus_A R-HSA-202430 Translocation of ZAP-70 to Immunological synapse 15/1095 19/10654 3.5951565294830126e-12 3.8084285269947166e-11 2.5047433091224203e-11 3120/3117/3119/3123/919/3115/3122/920/3113/915/917/916/7535/3932/3127 15 Rotavirus_A R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 15/1095 19/10654 3.5951565294830126e-12 3.8084285269947166e-11 2.5047433091224203e-11 5295/4893/6464/5290/5335/1950/867/3320/6654/2885/1956/3845/2549/3265/11140 15 Rotavirus_A R-HSA-111885 Opioid Signalling 34/1095 91/10654 5.359846335555714e-12 5.630090688608943e-11 3.702821749729335e-11 2788/3838/54331/5331/59345/2770/5578/10681/51764/94235/5330/5573/55970/10768/2792/2793/23236/2785/2783/2784/2782/2786/2771/5332/5580/1385/5518/115/801/1020/2791/2773/2790/2787 34 Rotavirus_A R-HSA-5654733 Negative regulation of FGFR4 signaling 19/1095 31/10654 6.143301781652767e-12 6.399272689221632e-11 4.208700606553343e-11 8823/8074/8817/2254/673/152831/2249/26281/6714/10818/867/2247/9965/2264/2885/2246/2251/5518/5781 19 Rotavirus_A R-HSA-2033519 Activated point mutants of FGFR2 14/1095 17/10654 6.8682969884824894e-12 7.030104531354278e-11 4.623588748621215e-11 8823/8074/8817/2254/2263/2249/26281/2248/2247/2255/27006/2246/2251/2252 14 Rotavirus_A R-HSA-9034015 Signaling by NTRK3 (TRKC) 14/1095 17/10654 6.8682969884824894e-12 7.030104531354278e-11 4.623588748621215e-11 5295/4908/5800/4893/6464/5290/3667/5335/6714/6654/2885/3845/3265/4916 14 Rotavirus_A R-HSA-1855204 Synthesis of IP3 and IP4 in the cytosol 18/1095 28/10654 6.91762285885261e-12 7.030104531354278e-11 4.623588748621215e-11 3635/5335/5331/5336/9651/3633/113026/5330/5333/89869/3636/23236/5728/84812/23007/5332/51196/801 18 Rotavirus_A R-HSA-5654228 Phospholipase C-mediated cascade; FGFR4 13/1095 15/10654 1.1532114021692259e-11 1.1532114021692259e-10 7.584489306056131e-11 5335/8823/8074/8817/2254/152831/2249/26281/2247/9965/2264/2246/2251 13 Rotavirus_A R-HSA-6785631 ERBB2 Regulates Cell Motility 13/1095 15/10654 1.1532114021692259e-11 1.1532114021692259e-10 7.584489306056131e-11 1839/685/2065/2069/2064/1950/145957/3084/2066/9542/10718/387/1956 13 Rotavirus_A R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 37/1095 108/10654 1.2771344421971212e-11 1.2669984545606362e-10 8.332848783257742e-11 5295/3592/3566/2309/3561/7184/356/3593/207/5292/7422/3553/3082/3383/301/3688/3565/4985/6774/3718/6772/4609/149233/1901/79923/3717/2247/3320/4843/6288/7157/3716/604/7040/51561/7297/3598 37 Rotavirus_A R-HSA-5655291 Signaling by FGFR4 in disease 11/1095 11/10654 1.292035617206437e-11 1.271688599612635e-10 8.363695126715521e-11 5295/4893/5290/5335/10818/2264/6654/2885/3845/2549/3265 11 Rotavirus_A R-HSA-416482 G alpha (12/13) signalling events 31/1095 80/10654 1.5373578443639728e-11 1.5013260198866922e-10 9.873984181317951e-11 2788/146/54331/59345/148/57580/7074/10681/6915/51764/94235/10451/55970/2792/9138/2793/2785/2783/2784/2782/695/2786/6654/7410/7409/387/147/2791/2790/2787/10672 31 Rotavirus_A R-HSA-8847993 ERBB2 Activates PTK6 Signaling 12/1095 13/10654 1.5500324479391766e-11 1.5019694262976516e-10 9.878215763692347e-11 1839/685/2065/2069/2064/1950/145957/3084/2066/9542/10718/1956 12 Rotavirus_A R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 14/1095 18/10654 2.797995370280544e-11 2.6698429105730384e-10 1.7559135268695097e-10 5295/8805/11052/26127/5290/613/9208/6774/6772/399687/2885/9846/7750/1523 14 Rotavirus_A R-HSA-210993 Tie2 Signaling 14/1095 18/10654 2.797995370280544e-11 2.6698429105730384e-10 1.7559135268695097e-10 5295/4893/6464/5290/5291/7010/6654/2885/285/5296/3845/3265/5781/284 14 Rotavirus_A R-HSA-420092 Glucagon-type ligand receptors 19/1095 33/10654 2.913679812438234e-11 2.759166489051358e-10 1.8146602340624092e-10 2788/54331/59345/10681/51764/94235/2642/55970/2792/2793/2785/2783/2641/2784/2782/2786/2791/2790/2787 19 Rotavirus_A R-HSA-202733 Cell surface interactions at the vascular wall 42/1095 137/10654 3.285660405093033e-11 3.0880266965160084e-10 2.0309463999823183e-10 5295/5777/3635/4893/6464/5290/5335/5291/2817/483/5175/7010/6383/338/50848/3688/6714/914/972/4067/682/2534/3690/6520/6654/2885/7525/51206/285/3685/3932/3897/5296/7040/3845/3265/5781/481/2207/2147/284/3655 42 Rotavirus_A R-HSA-5218921 VEGFR2 mediated cell proliferation 15/1095 21/10654 4.122094517662371e-11 3.8452374231925106e-10 2.528951938958611e-10 5170/5590/4893/5335/5579/7422/5578/10768/6714/5580/3791/3845/3265/801/8877 15 Rotavirus_A R-HSA-354192 Integrin alphaIIb beta3 signaling 17/1095 27/10654 4.39927243496947e-11 4.0434489291998803e-10 2.6593125168043005e-10 5170/6464/5770/5747/207/3674/7094/5908/6850/6714/3690/1445/6654/2885/1398/5906/9564 17 Rotavirus_A R-HSA-9006921 Integrin signaling 17/1095 27/10654 4.39927243496947e-11 4.0434489291998803e-10 2.6593125168043005e-10 5170/6464/5770/5747/207/3674/7094/5908/6850/6714/3690/1445/6654/2885/1398/5906/9564 17 Rotavirus_A R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 21/1095 42/10654 9.603442771235534e-11 8.762265302222202e-10 5.76280353771414e-10 2788/54331/59345/10681/51764/94235/5573/55970/2792/2793/2785/2783/2641/2784/2782/2786/8826/5906/2791/2790/2787 21 Rotavirus_A R-HSA-190322 FGFR4 ligand binding and activation 12/1095 14/10654 9.831515142268724e-11 8.9053579187216705e-010 5.856913292228736e-10 8823/8074/8817/2254/152831/2249/26281/2247/9965/2264/2246/2251 12 Rotavirus_A R-HSA-2029485 Role of phospholipids in phagocytosis 16/1095 25/10654 1.164324211700197e-10 1.0468498308751685e-9 6.884966045587424e-10 5295/5290/23646/5335/5291/2214/5336/2209/919/6850/10768/917/5580/5296/5581/2212 16 Rotavirus_A R-HSA-202427 Phosphorylation of CD3 and TCR zeta chains 15/1095 22/10654 1.1724718105801887e-10 1.0468498308751685e-9 6.884966045587424e-10 3120/3117/3119/3123/919/3115/3122/920/3113/915/917/1445/916/3932/3127 15 Rotavirus_A R-HSA-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle 19/1095 35/10654 1.1810393995157089e-10 1.047020744251515e-9 6.886090115877333e-10 7841/9695/10956/79139/91445/821/811/56886/10206/84447/5589/7415/80267/6400/2923/55741/51009/23193/267 19 Rotavirus_A R-HSA-1250342 PI3K events in ERBB4 signaling 10/1095 10/10654 1.2675048027230695e-10 1.1079587436390468e-9 7.286869716059751e-10 5295/1839/685/5290/2069/145957/3084/2066/9542/10718 10 Rotavirus_A R-HSA-8853334 Signaling by FGFR3 fusions in cancer 10/1095 10/10654 1.2675048027230695e-10 1.1079587436390468e-9 7.286869716059751e-10 5295/4893/5290/10818/2261/6654/2885/3845/2549/3265 10 Rotavirus_A R-HSA-76009 Platelet Aggregation (Plug Formation) 20/1095 39/10654 1.4939000695167207e-10 1.29678825478882e-9 8.528771595705842e-10 5170/6464/5770/5747/207/3674/7094/5908/6850/6714/4352/3690/1445/6654/2885/1398/5906/9564/2147/7066 20 Rotavirus_A R-HSA-9006931 Signaling by Nuclear Receptors 68/1095 299/10654 1.5161416440819547e-10 1.3070186586913404e-9 8.596055346845784e-10 5295/2788/5170/3838/5590/1839/4893/6464/685/5290/54331/5241/2309/5747/59345/5160/2770/8854/5360/207/2069/10681/1737/51764/94235/348/2100/1950/55970/1105/1655/6667/2792/6714/2099/4609/8503/5163/2793/10000/3320/5162/8243/2785/2783/2784/2782/3065/2066/2786/2771/208/1385/1025/1386/1956/5914/5296/3845/3265/801/8877/3480/2791/2773/2790/2787/6387 68 Rotavirus_A R-HSA-180292 GAB1 signalosome 13/1095 17/10654 2.144142234859446e-10 1.835738214776923e-9 1.207336038518549e-9 5295/1839/685/5290/2069/1950/6714/1445/2885/1956/2549/5781/5829 13 Rotavirus_A R-HSA-8863795 Downregulation of ERBB2 signaling 17/1095 29/10654 2.214224041677482e-10 1.8828435728550015e-9 1.23831648875769e-9 1839/685/2065/207/2069/2064/1950/10000/145957/3320/3084/2066/208/9542/10718/1956/11140 17 Rotavirus_A R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 40/1095 134/10654 2.392889312493234e-10 2.021021378794961e-9 1.3291938499695701e-9 5295/5170/9402/4893/6464/5290/2205/5335/4790/5291/3937/5336/10451/2206/5970/4792/6850/10768/7462/5701/27040/4067/5588/2534/695/7189/6654/2885/7410/7409/3702/9846/5296/3845/3265/801/997/2207/5879/7294 40 Rotavirus_A R-HSA-901042 Calnexin/calreticulin cycle 16/1095 26/10654 2.739021315591839e-10 2.2978366741542274e-9 1.5112508989595381e-9 9695/10956/91445/821/811/56886/10206/84447/5589/80267/6400/2923/55741/51009/23193/267 16 Rotavirus_A R-HSA-190241 FGFR2 ligand binding and activation 14/1095 20/10654 2.9049228841648645e-10 2.420769070137387e-9 1.5921015947598309e-9 8823/8074/8817/2254/2263/2249/26281/2248/2247/2255/27006/2246/2251/2252 14 Rotavirus_A R-HSA-373753 Nephrin family interactions 15/1095 23/10654 3.0508175255279707e-10 2.5255111966291148e-9 1.6609888375303907e-9 5295/4868/5290/5291/4690/7827/81/2534/87/89/23607/6709/88/8826/5296 15 Rotavirus_A R-HSA-202403 TCR signaling 37/1095 119/10654 3.1295846122843537e-10 2.5736715561548958e-9 1.6926631455637677e-9 5295/3120/5170/9402/3635/5290/5335/4790/5291/4690/3117/3119/3937/3123/919/3115/3122/920/5970/4792/50852/3113/5701/27040/915/5588/917/5728/1445/916/7189/7535/3702/3932/5296/3127/997 37 Rotavirus_A R-HSA-163359 Glucagon signaling in metabolic regulation 18/1095 33/10654 3.306673529537516e-10 2.6839882544947367e-9 1.7652166962192755e-9 2788/54331/59345/51764/94235/2642/5573/55970/2785/2783/2641/2784/2782/2786/115/2791/2790/2787 18 Rotavirus_A R-HSA-5654726 Negative regulation of FGFR1 signaling 18/1095 33/10654 3.306673529537516e-10 2.6839882544947367e-9 1.7652166962192755e-9 8074/2260/2254/673/2249/26281/6714/10818/2248/867/2247/2255/27006/2885/2246/2251/5518/5781 18 Rotavirus_A R-HSA-177929 Signaling by EGFR 22/1095 49/10654 4.86513208632266e-10 3.923493618002145e-9 2.5804198026607795e-9 5295/1839/4893/6464/685/5290/5335/2069/1950/6714/867/1445/998/6654/30011/2885/1956/3845/2549/3265/5781/5829 22 Rotavirus_A R-HSA-4086398 Ca2+ pathway 25/1095 62/10654 5.309996456503786e-10 4.254804852967777e-9 2.7983179706676503e-9 2788/54331/5331/1499/59345/5578/10681/51764/94235/5330/55970/2792/2793/23236/2785/2783/2784/2782/2786/3845/801/2791/7976/2790/2787 25 Rotavirus_A R-HSA-446203 Asparagine N-linked glycosylation 67/1095 304/10654 8.585330535297105e-10 6.835454247848013e-9 4.495570330584674e-9 9919/10113/6811/23256/22820/7841/6483/9695/8703/10956/79139/1650/2801/10484/432/91445/10802/821/5861/2157/830/811/6184/56886/9554/10206/55577/84447/22872/5589/8655/84061/1315/3998/7415/8775/2804/81876/11316/80267/64377/5265/6400/2923/375056/9632/3630/6185/4905/9276/55741/6709/51332/5537/9871/51009/51128/3703/23193/10945/6396/51046/375/267/26958/10652/10427 67 Rotavirus_A R-HSA-1500931 Cell-Cell communication 38/1095 129/10654 1.0274295723498543e-9 8.128398515426063e-9 5.345919360461267e-9 5295/5777/4868/3918/5290/7305/5291/1495/1499/5584/5747/4690/2316/7827/50848/3688/1500/3611/6714/1003/999/81/2534/10979/3728/87/1000/89/23607/2885/6709/88/8826/5296/5781/3691/5829/3655 38 Rotavirus_A R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 10/1095 11/10654 1.2650517212747388e-9 9.945375167254235e-9 6.540916215263629e-9 627/4893/4915/10818/4909/6654/2885/3845/3265/5781 10 Rotavirus_A R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 20/1095 43/10654 1.3908939489768048e-9 1.0866358976381288e-8 7.146632724676874e-9 2788/54331/59345/10681/51764/94235/5573/55970/2792/2793/2785/2783/2784/2782/2786/115/551/2791/2790/2787 20 Rotavirus_A R-HSA-1433559 Regulation of KIT signaling 12/1095 16/10654 1.6146813062018432e-9 1.2458960696001875e-8 8.194061729328394e-9 5777/3815/5578/6714/867/4067/2534/6654/2885/7525/3932/4254 12 Rotavirus_A R-HSA-5654219 Phospholipase C-mediated cascade: FGFR1 12/1095 16/10654 1.6146813062018432e-9 1.2458960696001875e-8 8.194061729328394e-9 5335/8074/2260/2254/2249/26281/2248/2247/2255/27006/2246/2251 12 Rotavirus_A R-HSA-6806834 Signaling by MET 28/1095 79/10654 1.6549734090491927e-9 1.2691513873076632e-8 8.347008281998189e-9 5295/3918/4893/6464/5290/5770/5747/284217/5908/3082/382/3912/3688/6774/4233/6714/867/6654/30011/2885/1398/5906/3845/2549/3265/1399/5781/5879 28 Rotavirus_A R-HSA-389357 CD28 dependent PI3K/Akt signaling 14/1095 22/10654 1.9646636141130446e-9 1.4974570229520156e-8 9.848538399372836e-9 5295/5170/5290/207/941/8503/10000/2534/942/208/2475/3932/5296/940 14 Rotavirus_A R-HSA-390466 Chaperonin-mediated protein folding 31/1095 95/10654 2.308713751113685e-9 1.749025569025519e-8 1.1503065005548886e-8 2788/54331/2629/59345/2770/10575/10681/51764/94235/7203/908/55970/6774/1457/2792/2793/26270/2785/55294/2783/2784/2782/5082/7157/2786/2771/8877/2791/2773/2790/2787 31 Rotavirus_A R-HSA-5218920 VEGFR2 mediated vascular permeability 16/1095 29/10654 2.5925672927211194e-9 1.940544380779281e-8 1.2762653990640998e-8 5170/1495/1499/207/10451/1500/1003/10000/3320/3728/208/7410/2475/7409/801/5879 16 Rotavirus_A R-HSA-5654732 Negative regulation of FGFR3 signaling 16/1095 29/10654 2.5925672927211194e-9 1.940544380779281e-8 1.2762653990640998e-8 8823/8074/8817/2254/673/2249/26281/6714/10818/2261/867/2247/2885/2246/5518/5781 16 Rotavirus_A R-HSA-1660499 Synthesis of PIPs at the plasma membrane 22/1095 53/10654 3.0217541941307192e-9 2.2483290134901184e-8 1.478690492240659e-8 5295/23396/3635/5305/5290/5291/5868/79837/8395/8871/5287/8503/146850/23533/3636/5294/5728/8396/5293/5296/8394/375 22 Rotavirus_A R-HSA-180336 SHC1 events in EGFR signaling 11/1095 14/10654 3.505590125395355e-9 2.5776397980848194e-8 1.6952729956246268e-8 1839/4893/6464/685/2069/1950/6654/2885/1956/3845/3265 11 Rotavirus_A R-HSA-9027284 Erythropoietin activates RAS 11/1095 14/10654 3.505590125395355e-9 2.5776397980848194e-8 1.6952729956246268e-8 4893/6464/4067/3717/6654/2885/7409/8660/3845/3265/1399 11 Rotavirus_A R-HSA-2682334 EPH-Ephrin signaling 30/1095 92/10654 4.261849752896735e-9 3.097274529721464e-8 2.0370285538631277e-8 5747/1947/4627/7074/10627/10451/23385/6383/2046/2902/6714/2050/4067/2047/2534/1946/998/1948/4628/2048/7525/1942/7410/10097/1213/387/1211/3265/1969/5879 30 Rotavirus_A R-HSA-877300 Interferon gamma signaling 30/1095 92/10654 4.261849752896735e-9 3.097274529721464e-8 2.0370285538631277e-8 3135/3120/5777/5770/3117/3107/3119/9830/3123/2209/3383/7706/3115/3122/567/3113/6772/3106/3459/7341/3717/3458/5580/3716/3133/3134/3127/5781/3105/5724 30 Rotavirus_A R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission 50/1095 206/10654 4.338594732849853e-9 3.13482278385105e-8 2.061723447736986e-8 2788/5170/5563/3838/4893/54331/5579/5331/27020/59345/2770/4646/5578/2036/10681/51764/94235/5330/5573/2902/55970/2792/6714/1138/2793/2566/23236/3084/2785/2783/2784/2782/2066/4905/2786/2771/1739/88/1385/3845/115/3265/801/2791/2554/2773/5879/4193/2790/2787 50 Rotavirus_A R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 10/1095 12/10654 6.887466260244636e-9 4.947892428336663e-8 3.254150725499735e-8 5295/5290/5291/4067/23533/3717/5294/8660/5293/2549 10 Rotavirus_A R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 20/1095 47/10654 9.446955216497536e-9 6.634097764394336e-8 4.363141350730087e-8 4893/5604/3674/7094/5908/7414/673/6714/5605/3717/3690/1445/5894/8826/5906/3845/3265/369/801/5245 20 Rotavirus_A R-HSA-6802949 Signaling by RAS mutants 20/1095 47/10654 9.446955216497536e-9 6.634097764394336e-8 4.363141350730087e-8 4893/5604/3674/7094/5908/7414/673/6714/5605/3717/3690/1445/5894/8826/5906/3845/3265/369/801/5245 20 Rotavirus_A R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 20/1095 47/10654 9.446955216497536e-9 6.634097764394336e-8 4.363141350730087e-8 4893/5604/3674/7094/5908/7414/673/6714/5605/3717/3690/1445/5894/8826/5906/3845/3265/369/801/5245 20 Rotavirus_A R-HSA-9649948 Signaling downstream of RAS mutants 20/1095 47/10654 9.446955216497536e-9 6.634097764394336e-8 4.363141350730087e-8 4893/5604/3674/7094/5908/7414/673/6714/5605/3717/3690/1445/5894/8826/5906/3845/3265/369/801/5245 20 Rotavirus_A R-HSA-399997 Acetylcholine regulates insulin secretion 9/1095 10/10654 1.128336043352258e-8 7.879441643521355e-8 5.182184356707519e-8 5331/1131/5578/5330/2769/2767/23236/2776/9630 9 Rotavirus_A R-HSA-391251 Protein folding 31/1095 101/10654 1.211781948092711e-8 8.415152417310493e-8 5.53451287403747e-8 2788/54331/2629/59345/2770/10575/10681/51764/94235/7203/908/55970/6774/1457/2792/2793/26270/2785/55294/2783/2784/2782/5082/7157/2786/2771/8877/2791/2773/2790/2787 31 Rotavirus_A R-HSA-1251985 Nuclear signaling by ERBB4 16/1095 32/10654 1.7017343892090176e-8 1.1752309317741835e-7 7.729308275500104e-8 1839/685/5241/2069/51741/23385/348/6714/2099/145957/3084/2066/9542/10718/11033/6387 16 Rotavirus_A R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 17/1095 36/10654 1.8191949908456893e-8 1.249447109097314e-7 8.217416355410546e-8 4893/5604/3674/7094/5908/7414/673/6714/5605/3690/1445/5894/8826/5906/3845/3265/369 17 Rotavirus_A R-HSA-186797 Signaling by PDGF 22/1095 58/10654 2.216442104863078e-8 1.5139631863818837e-7 9.95709683001475e-8 5295/4893/5290/5335/5291/4690/6774/6772/6714/5159/6654/2885/1398/5154/5155/5296/9564/3845/3265/1399/5781/5156 22 Rotavirus_A R-HSA-179812 GRB2 events in EGFR signaling 10/1095 13/10654 2.7084202117765956e-8 1.8201748735057767e-7 1.1971002747014833e-7 1839/4893/685/2069/1950/6654/2885/1956/3845/3265 10 Rotavirus_A R-HSA-190375 FGFR2c ligand binding and activation 10/1095 13/10654 2.7084202117765956e-8 1.8201748735057767e-7 1.1971002747014833e-7 8823/8074/8817/2254/2263/2249/26281/2247/2246/2251 10 Rotavirus_A R-HSA-5654227 Phospholipase C-mediated cascade; FGFR3 10/1095 13/10654 2.7084202117765956e-8 1.8201748735057767e-7 1.1971002747014833e-7 5335/8823/8074/8817/2254/2249/26281/2261/2247/2246 10 Rotavirus_A R-HSA-190242 FGFR1 ligand binding and activation 11/1095 16/10654 3.45948463820653e-8 2.312489731421477e-7 1.5208879833601465e-7 8074/2260/2254/2249/26281/2248/2247/2255/27006/2246/2251 11 Rotavirus_A R-HSA-3928662 EPHB-mediated forward signaling 18/1095 42/10654 4.56927095712994e-8 3.038079093836396e-7 1.9980966503462956e-7 5747/1947/7074/6383/2902/6714/2050/4067/2047/2534/998/1948/2048/7525/10097/387/3265/5879 18 Rotavirus_A R-HSA-983705 Signaling by the B Cell Receptor (BCR) 32/1095 112/10654 4.790775872744242e-8 3.1685025613387844e-7 2.0838741056047083e-7 5295/5777/4893/4790/5579/4690/5336/930/5970/4792/6850/10768/25780/5701/4067/29760/2534/695/974/6654/30011/2885/7409/5293/118788/3845/27071/3265/801/973/933/6786 32 Rotavirus_A R-HSA-3928665 EPH-ephrin mediated repulsion of cells 20/1095 51/10654 5.0160189698270315e-8 3.3000124801493625e-7 2.170366102734023e-7 1947/7074/10451/23385/2046/6714/2050/4067/2047/2534/1946/1948/2048/7525/1942/7410/1213/1211/1969/5879 20 Rotavirus_A R-HSA-187687 Signalling to ERKs 16/1095 34/10654 5.110778109174116e-8 3.344750071449029e-7 2.1997893101487933e-7 4893/6464/5604/673/6714/5605/10818/4914/4803/6654/2885/1398/5906/3845/3265/1399 16 Rotavirus_A R-HSA-400451 Free fatty acids regulate insulin secretion 9/1095 11/10654 5.6365749638638225e-8 3.6318137653761744e-7 2.388586569060036e-7 5331/5330/2769/2767/2864/23236/2776/9630/2181 9 Rotavirus_A R-HSA-8875555 MET activates RAP1 and RAC1 9/1095 11/10654 5.6365749638638225e-8 3.6318137653761744e-7 2.388586569060036e-7 5908/3082/4233/2885/1398/5906/2549/1399/5879 9 Rotavirus_A R-HSA-9020956 Interleukin-27 signaling 9/1095 11/10654 5.6365749638638225e-8 3.6318137653761744e-7 2.388586569060036e-7 10148/821/6774/6772/3717/9466/3716/246778/7297 9 Rotavirus_A R-HSA-445717 Aquaporin-mediated transport 20/1095 52/10654 7.370914182558125e-8 4.724944988819311e-7 3.107521714751901e-7 2788/54331/59345/10681/51764/94235/5573/55970/2792/2793/2785/2783/2784/2782/2786/115/551/2791/2790/2787 20 Rotavirus_A R-HSA-977444 GABA B receptor activation 17/1095 39/10654 7.997070817583445e-8 5.074283513695079e-7 3.337276146691249e-7 2788/54331/2770/94235/55970/2792/2793/2785/2783/2784/2782/2786/2771/115/2773/2790/2787 17 Rotavirus_A R-HSA-991365 Activation of GABAB receptors 17/1095 39/10654 7.997070817583445e-8 5.074283513695079e-7 3.337276146691249e-7 2788/54331/2770/94235/55970/2792/2793/2785/2783/2784/2782/2786/2771/115/2773/2790/2787 17 Rotavirus_A R-HSA-202424 Downstream TCR signaling 29/1095 98/10654 8.755026060860578e-8 5.527162917209961e-7 3.6351277796555617e-7 5295/3120/5170/3635/5290/4790/5291/3117/3119/3123/919/3115/3122/920/5970/4792/50852/3113/5701/915/5588/917/5728/916/7189/3932/5296/3127/997 29 Rotavirus_A R-HSA-913531 Interferon Signaling 46/1095 199/10654 8.848161027633261e-8 5.557890092734461e-7 3.655336557832096e-7 3839/3135/3120/5777/3838/5335/55706/7175/5770/9631/3117/3107/3119/10410/2316/9830/3123/2209/79023/3383/57122/7706/3115/3122/567/3113/6772/23279/3106/3840/3459/7341/3717/3458/8086/5580/3716/3133/3134/3127/6396/7297/5781/55746/3105/5724 46 Rotavirus_A R-HSA-5674135 MAP2K and MAPK activation 17/1095 40/10654 1.2584913935203555e-7 7.865571209502222e-7 5.173061991259987e-7 4893/5604/3674/7094/5908/7414/673/6714/5605/3690/1445/5894/8826/5906/3845/3265/369 17 Rotavirus_A R-HSA-204005 COPII-mediated vesicle transport 23/1095 68/10654 1.2781215609581014e-7 7.948517170137447e-7 5.227614239896712e-7 9919/10113/6811/23256/2801/10484/10802/5861/2157/9554/22872/3998/8775/81876/5265/9632/4905/5537/9871/51128/6396/10652/10427 23 Rotavirus_A R-HSA-389513 CTLA4 inhibitory signaling 12/1095 21/10654 1.5951236058864913e-7 9.822189691419282e-7 6.459899072840808e-7 207/941/6714/4067/10000/2534/942/208/7525/3932/5518/5781 12 Rotavirus_A R-HSA-445144 Signal transduction by L1 12/1095 21/10654 1.5951236058864913e-7 9.822189691419282e-7 6.459899072840808e-7 5604/3674/2260/3688/1457/5605/3690/7410/3685/3897/1956/5879 12 Rotavirus_A R-HSA-1483249 Inositol phosphate metabolism 19/1095 50/10654 1.9576237026879394e-7 1.199524327627414e-6 7.889082104227455e-7 3635/5335/5331/5336/9651/3633/113026/5330/5333/9807/89869/3636/23236/5728/84812/23007/5332/51196/801 19 Rotavirus_A R-HSA-1839130 Signaling by activated point mutants of FGFR3 9/1095 12/10654 2.048005997738186e-7 1.2248839699391066e-6 8.055868467557409e-7 8823/8074/8817/2254/2249/26281/2261/2247/2246 9 Rotavirus_A R-HSA-2033514 FGFR3 mutant receptor activation 9/1095 12/10654 2.048005997738186e-7 1.2248839699391066e-6 8.055868467557409e-7 8823/8074/8817/2254/2249/26281/2261/2247/2246 9 Rotavirus_A R-HSA-389359 CD28 dependent Vav1 pathway 9/1095 12/10654 2.048005997738186e-7 1.2248839699391066e-6 8.055868467557409e-7 941/2534/998/942/2885/7409/3932/940/5879 9 Rotavirus_A R-HSA-8984722 Interleukin-35 Signalling 9/1095 12/10654 2.048005997738186e-7 1.2248839699391066e-6 8.055868467557409e-7 10148/3592/821/6774/6772/3717/9466/3716/7297 9 Rotavirus_A R-HSA-9020558 Interleukin-2 signaling 9/1095 12/10654 2.048005997738186e-7 1.2248839699391066e-6 8.055868467557409e-7 6464/3561/3560/6850/3718/3558/3716/3932/3559 9 Rotavirus_A R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 11/1095 18/10654 2.0733529236029968e-7 1.2341386450017837e-6 8.116735004180153e-7 1839/4893/5578/887/6654/2885/1385/1956/3845/3265/2520 11 Rotavirus_A R-HSA-1296041 Activation of G protein gated Potassium channels 13/1095 25/10654 2.125230798682046e-7 1.2472011729354728e-6 8.202645187895617e-7 2788/54331/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 13 Rotavirus_A R-HSA-1296059 G protein gated Potassium channels 13/1095 25/10654 2.125230798682046e-7 1.2472011729354728e-6 8.202645187895617e-7 2788/54331/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 13 Rotavirus_A R-HSA-997272 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits 13/1095 25/10654 2.125230798682046e-7 1.2472011729354728e-6 8.202645187895617e-7 2788/54331/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 13 Rotavirus_A R-HSA-391903 Eicosanoid ligand-binding receptors 10/1095 15/10654 2.3425023051125848e-7 1.3682840567246408e-6 8.9989881962269e-7 6915/5737/57105/2840/10800/5733/56413/1241/5739/5731 10 Rotavirus_A R-HSA-1839126 FGFR2 mutant receptor activation 15/1095 33/10654 2.38499596916453e-7 1.3866255634677499e-6 9.11961739004895e-7 8823/8074/8817/2254/2263/2249/26281/2248/2247/2255/27006/2246/2251/2252/22916 15 Rotavirus_A R-HSA-977443 GABA receptor activation 20/1095 56/10654 3.074146453220512e-7 1.7790199382063147e-6 1.1700333235697953e-6 2788/54331/27020/2770/94235/55970/2792/2793/2566/2785/2783/2784/2782/2786/2771/115/2554/2773/2790/2787 20 Rotavirus_A R-HSA-6802957 Oncogenic MAPK signaling 23/1095 71/10654 3.1199729672098706e-7 1.7972194511577595e-6 1.1820028558772298e-6 27044/8805/4893/5604/3674/7094/5908/7414/673/6714/5605/3717/3690/1445/5894/56829/8826/5906/3845/3265/369/801/5245 23 Rotavirus_A R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 21/1095 61/10654 3.196787522407158e-7 1.833020368352728e-6 1.2055485538387206e-6 2214/5747/4690/10006/4627/2209/10451/919/6850/4641/917/3320/998/695/2885/1398/7410/10097/7409/2212/5879 21 Rotavirus_A R-HSA-447115 Interleukin-12 family signaling 20/1095 57/10654 4.2831448948827625e-7 2.4381033369629967e-6 1.603502068352085e-6 10148/3592/3593/821/5908/3313/6774/6772/149233/3717/9466/3458/998/3716/3594/51561/375/246778/7297/5034 20 Rotavirus_A R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 34/1095 134/10654 4.2910618730548746e-7 2.4381033369629967e-6 1.603502068352085e-6 351/7018/5579/51097/7424/2316/5175/3674/7094/3959/7422/5578/3082/7414/2157/3827/1950/78991/1191/197/81/5265/3309/9948/1/3690/87/5345/88/5154/3479/5155/7040/801 34 Rotavirus_A R-HSA-6802952 Signaling by BRAF and RAF fusions 22/1095 67/10654 4.314287206193768e-7 2.440207695810955e-6 1.604886071939668e-6 27044/8805/4893/5604/3674/7094/5908/7414/673/6714/5605/3717/3690/1445/5894/56829/8826/5906/3845/3265/369/801 22 Rotavirus_A R-HSA-611105 Respiratory electron transport 28/1095 100/10654 5.187814152962333e-7 2.921066527568881e-6 1.9211393330789862e-6 4722/4723/4702/2110/7388/1345/4719/4704/4729/6389/1351/7385/4728/374291/1350/10128/27089/2108/4726/7384/4716/4698/1327/4697/4720/9167/1537/51079 28 Rotavirus_A R-HSA-418594 G alpha (i) signalling events 74/1095 406/10654 5.399259242537071e-7 3.026490606803291e-6 1.990475085400733e-6 2788/10316/4544/4543/3838/351/7852/54331/5331/2817/59345/375790/23566/2358/2770/84539/5578/846/10681/51764/94235/5330/301/6383/2912/5573/348/3827/338/56923/2357/4985/55970/186/10768/2792/6714/2840/5367/1901/3949/2793/5588/5733/23236/2785/2783/624/2784/4035/2782/6288/2786/2771/5332/183/5580/1385/2847/57121/5518/9170/10874/115/801/1020/1902/129521/2791/2773/2790/2787/6387/623 74 Rotavirus_A R-HSA-199977 ER to Golgi Anterograde Transport 37/1095 154/10654 5.857747361273463e-7 3.2688322328534954e-6 2.1498593464072256e-6 9919/10113/6811/23256/22820/2801/10484/10802/5861/2157/830/9554/22872/8655/1315/3998/8775/2804/81876/11316/5265/375056/9632/3630/4905/9276/6709/51332/5537/9871/51128/10945/6396/375/26958/10652/10427 37 Rotavirus_A R-HSA-375165 NCAM signaling for neurite out-growth 21/1095 63/10654 5.929456527569791e-7 3.2941425153165507e-6 2.166505519547138e-6 5786/2674/4893/5747/375790/2675/4902/2260/2668/6714/64096/2534/6654/2885/6709/51332/1385/9048/3845/5623/3265 21 Rotavirus_A R-HSA-1483255 PI Metabolism 25/1095 84/10654 5.978762330534074e-7 3.30683757219805e-6 2.1748548580098337e-6 5295/23396/3635/5305/5290/5291/5868/79837/8395/200576/5289/8871/5287/8503/146850/23533/3636/5294/5728/8396/5293/5296/8394/375/30849 25 Rotavirus_A R-HSA-190239 FGFR3 ligand binding and activation 9/1095 13/10654 6.046624944999345e-7 3.315035605811045e-6 2.1802465752744636e-6 8823/8074/8817/2254/2249/26281/2261/2247/2246 9 Rotavirus_A R-HSA-190372 FGFR3c ligand binding and activation 9/1095 13/10654 6.046624944999345e-7 3.315035605811045e-6 2.1802465752744636e-6 8823/8074/8817/2254/2249/26281/2261/2247/2246 9 Rotavirus_A R-HSA-3858494 Beta-catenin independent WNT signaling 35/1095 146/10654 1.2437526235722455e-6 6.789042705088677e-6 4.46504619172569e-6 2788/54331/5579/5331/1499/59345/5578/10681/51764/94235/5330/64750/55970/2792/5881/5701/2793/23236/5880/2785/2783/2784/2782/2786/1857/1213/387/1211/3845/801/2791/7976/5879/2790/2787 35 Rotavirus_A R-HSA-1236977 Endosomal/Vacuolar pathway 8/1095 11/10654 1.5097163568039763e-6 8.13424761209039e-6 5.3497662189832385e-6 3135/3107/567/3106/4012/3133/3134/3105 8 Rotavirus_A R-HSA-1839122 Signaling by activated point mutants of FGFR1 8/1095 11/10654 1.5097163568039763e-6 8.13424761209039e-6 5.3497662189832385e-6 8074/2260/2254/2249/26281/2247/2246/2251 8 Rotavirus_A R-HSA-8851805 MET activates RAS signaling 8/1095 11/10654 1.5097163568039763e-6 8.13424761209039e-6 5.3497662189832385e-6 4893/6464/3082/4233/6654/2885/3845/3265 8 Rotavirus_A R-HSA-169893 Prolonged ERK activation events 9/1095 14/10654 1.5381996668221804e-6 8.181913121394576e-6 5.381115071839298e-6 5604/673/5605/10818/4914/4803/1398/5906/1399 9 Rotavirus_A R-HSA-877312 Regulation of IFNG signaling 9/1095 14/10654 1.5381996668221804e-6 8.181913121394576e-6 5.381115071839298e-6 5777/5770/6772/3459/7341/3717/3458/3716/5781 9 Rotavirus_A R-HSA-8983432 Interleukin-15 signaling 9/1095 14/10654 1.5381996668221804e-6 8.181913121394576e-6 5.381115071839298e-6 6464/3561/3560/6774/3718/6654/2885/3716/9846 9 Rotavirus_A R-HSA-114608 Platelet degranulation 32/1095 129/10654 1.5947620073669792e-6 8.446832666138661e-6 5.555348473477301e-6 351/7018/51097/7424/2316/5175/3674/7094/3959/7422/3082/7414/2157/3827/1950/78991/1191/197/81/5265/3309/9948/1/3690/87/5345/88/5154/3479/5155/7040/801 32 Rotavirus_A R-HSA-901032 ER Quality Control Compartment (ERQC) 11/1095 21/10654 1.71538941898048e-6 9.047412547365401e-6 5.950340378519899e-6 9695/10956/91445/56886/10206/84447/80267/6400/55741/51009/267 11 Rotavirus_A R-HSA-3371556 Cellular response to heat stress 25/1095 89/10654 1.963754207224829e-6 1.0313835121979143e-5 6.783246509697442e-6 6118/55706/7175/9631/1915/3308/9530/10049/10013/545/79023/57122/3313/23279/7415/6119/2932/3309/3320/8086/2475/6117/6396/57521/55746 25 Rotavirus_A R-HSA-354194 GRB2:SOS provides linkage to MAPK signaling for Integrins 9/1095 15/10654 3.494123821288558e-6 1.819856156921124e-5 1.1968906598361246e-5 5747/3674/7094/5908/6714/3690/6654/2885/5906 9 Rotavirus_A R-HSA-372708 p130Cas linkage to MAPK signaling for integrins 9/1095 15/10654 3.494123821288558e-6 1.819856156921124e-5 1.1968906598361246e-5 5747/3674/7094/5908/6714/3690/1398/5906/9564 9 Rotavirus_A R-HSA-948021 Transport to the Golgi and subsequent modification 40/1095 185/10654 3.6821983262499088e-6 1.9098539036565918e-5 1.2560807568469882e-5 9919/10113/6811/23256/22820/8703/2801/10484/10802/5861/2157/830/9554/22872/8655/1315/3998/8775/2804/81876/11316/64377/5265/375056/9632/3630/4905/9276/6709/51332/5537/9871/51128/10945/6396/51046/375/26958/10652/10427 40 Rotavirus_A R-HSA-170968 Frs2-mediated activation 8/1095 12/10654 4.119547870864305e-6 2.1104241141722875e-5 1.3879926174051005e-5 5604/673/5605/10818/4914/4803/5906/1399 8 Rotavirus_A R-HSA-190373 FGFR1c ligand binding and activation 8/1095 12/10654 4.119547870864305e-6 2.1104241141722875e-5 1.3879926174051005e-5 8074/2260/2254/2249/26281/2247/2246/2251 8 Rotavirus_A R-HSA-417957 P2Y receptors 8/1095 12/10654 4.119547870864305e-6 2.1104241141722875e-5 1.3879926174051005e-5 10161/27334/5032/2840/5028/5031/5029/2846 8 Rotavirus_A R-HSA-1296065 Inwardly rectifying K+ channels 13/1095 31/10654 4.669774475097189e-6 2.3825379974985656e-5 1.5669576219337936e-5 2788/54331/94235/55970/2792/2793/2785/2783/2784/2782/2786/2790/2787 13 Rotavirus_A R-HSA-8875878 MET promotes cell motility 15/1095 41/10654 6.598762447894676e-6 3.3530296991334736e-5 2.205234690545889e-5 3918/5747/284217/5908/3082/3912/3688/4233/6714/2885/1398/5906/2549/1399/5879 15 Rotavirus_A R-HSA-112315 Transmission across Chemical Synapses 52/1095 272/10654 6.669315267257836e-6 3.375159548207407e-5 2.2197891428631453e-5 2788/5170/5563/3838/4893/54331/1312/5579/5331/27020/59345/2770/4646/5578/2036/10681/51764/94235/5330/5573/2902/55970/2792/6714/1138/2793/2566/23236/3084/2785/2783/6532/2784/2782/2066/4905/2786/2771/1739/88/1385/3845/115/3265/801/2791/2554/2773/5879/4193/2790/2787 52 Rotavirus_A R-HSA-5673000 RAF activation 13/1095 32/10654 7.1290914001576745e-6 3.5932920363697954e-5 2.363251436130367e-5 4893/5604/673/6714/5605/3717/5894/5518/3845/3265/369/801/5245 13 Rotavirus_A R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 11/1095 24/10654 9.068169714069785e-6 4.552294033167563e-5 2.993971907287467e-5 1839/685/2309/5747/207/2069/1950/10000/208/1385/1956 11 Rotavirus_A R-HSA-8856828 Clathrin-mediated endocytosis 33/1095 146/10654 9.646281294588068e-6 4.823140647294034e-5 3.172103448872961e-5 5869/23396/1839/685/7018/5868/10618/2069/1080/29978/382/338/1950/920/8871/7037/3949/867/915/917/3482/185/1861/30011/2885/10097/1213/1956/1211/51429/6869/551/154 33 Rotavirus_A R-HSA-5694530 Cargo concentration in the ER 13/1095 33/10654 1.0663172886141748e-5 5.3103450628195955e-5 3.492530100262825e-5 10113/6811/10484/10802/2157/9554/3998/5265/375056/9632/9871/51128/10427 13 Rotavirus_A R-HSA-190377 FGFR2b ligand binding and activation 7/1095 10/10654 1.0793284807386864e-5 5.311655909147079e-5 3.4933922231948366e-5 2263/2248/2247/2255/27006/2246/2252 7 Rotavirus_A R-HSA-74749 Signal attenuation 7/1095 10/10654 1.0793284807386864e-5 5.311655909147079e-5 3.4933922231948366e-5 3643/6464/3667/3630/6654/2885/8660 7 Rotavirus_A R-HSA-8875656 MET receptor recycling 7/1095 10/10654 1.0793284807386864e-5 5.311655909147079e-5 3.4933922231948366e-5 3082/382/4233/2885/1398/2549/1399 7 Rotavirus_A R-HSA-1428517 The citric acid (TCA) cycle and respiratory electron transport 37/1095 174/10654 1.2600538318870615e-5 6.176734470034615e-5 4.062340733555397e-5 3419/4722/4723/4702/2110/5160/7388/1743/1345/4719/4704/1737/4729/7416/6389/1351/7385/4728/374291/5163/1350/23530/682/5162/10128/27089/2108/4726/7384/4716/4698/1327/4697/4720/9167/1537/51079 37 Rotavirus_A R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 11/1095 25/10654 1.4695013954911271e-5 7.175299782671519e-5 4.719081372855964e-5 5170/2309/842/207/7249/2932/10000/208/2475/1385/4193 11 Rotavirus_A R-HSA-373755 Semaphorin interactions 19/1095 65/10654 1.767161833321606e-5 8.595145103704309e-5 5.652891221888899e-5 23396/7305/4627/7094/10627/2064/3688/3672/54209/4233/2932/3320/2534/4628/387/6237/1020/5879/2242 19 Rotavirus_A R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 26/1095 106/10654 1.8444101595278283e-5 8.936095734146455e-5 5.87712906809969e-5 1839/685/7018/10618/2069/1080/29978/338/1950/920/7037/3949/867/915/917/3482/185/1861/30011/2885/1213/1956/1211/6869/551/154 26 Rotavirus_A R-HSA-3928663 EPHA-mediated growth cone collapse 12/1095 30/10654 1.9454903900630482e-5 9.38943238447417e-5 6.175281425073119e-5 4627/10627/2046/6714/4067/2534/1946/4628/7525/1942/387/1969 12 Rotavirus_A R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 8/1095 14/10654 2.0683584214680727e-5 9.944030872442657e-5 6.540032093791762e-5 4893/1398/387/9564/3845/3265/5829/5879 8 Rotavirus_A R-HSA-1059683 Interleukin-6 signaling 7/1095 11/10654 2.7039529595906903e-5 1.294996628156461e-4 8.51698835023323e-5 6774/6772/867/3717/3716/7297/5781 7 Rotavirus_A R-HSA-163200 Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 28/1095 123/10654 3.90358218680302e-5 1.8623960814899903e-4 1.2248684965420484e-4 4722/4723/4702/2110/7388/1345/4719/4704/4729/6389/1351/7385/4728/374291/1350/10128/27089/2108/4726/7384/4716/4698/1327/4697/4720/9167/1537/51079 28 Rotavirus_A R-HSA-2980766 Nuclear Envelope Breakdown 16/1095 52/10654 4.016449479526692e-5 1.901727973260744e-4 1.250736460729803e-4 55706/7175/5579/9631/5578/79023/57122/23279/7444/8815/8086/2010/23592/6396/55746/7112 16 Rotavirus_A R-HSA-381070 IRE1alpha activates chaperones 16/1095 52/10654 4.016449479526692e-5 1.901727973260744e-4 1.250736460729803e-4 10113/10525/1200/6464/9695/37/7094/7494/58477/84447/22872/5611/10130/3309/6745/9820 16 Rotavirus_A R-HSA-3928664 Ephrin signaling 9/1095 19/10654 4.400468969059994e-5 2.0756929099339597e-4 1.3651504527649873e-4 1947/10627/6714/2050/2047/2534/1948/2048/5879 9 Rotavirus_A R-HSA-3371453 Regulation of HSF1-mediated heat shock response 19/1095 69/10654 4.4503358015502604e-5 2.0913232150142198e-4 1.375430257621984e-4 6118/55706/7175/9631/3308/9530/10049/545/79023/57122/3313/23279/6119/2932/3309/8086/6117/6396/55746 19 Rotavirus_A R-HSA-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 29/1095 132/10654 5.7275202056176095e-5 2.6814233172367085e-4 1.76352977748368e-4 3135/7305/912/2214/3107/29121/930/3824/910/2209/3383/925/919/3688/54209/567/926/3106/915/999/917/916/10870/3133/3134/958/933/3105/959 29 Rotavirus_A R-HSA-3371511 HSF1 activation 7/1095 12/10654 5.9127504010966526e-5 2.7571213049105975e-4 1.8133151487454124e-4 6118/1915/10013/7415/6119/3320/6117 7 Rotavirus_A R-HSA-3000171 Non-integrin membrane-ECM interactions 17/1095 59/10654 5.9333250481676066e-5 2.7571213049105975e-4 1.8133151487454124e-4 3918/375790/5578/284217/6383/3912/3688/2247/3690/87/3685/5154/5155/7040/3691/4921/3655 17 Rotavirus_A R-HSA-982772 Growth hormone receptor signaling 10/1095 24/10654 6.419568517964173e-5 2.9720224620204507e-4 1.9546522466003978e-4 5777/3667/5770/2690/6774/6772/4067/3717/2688/8660 10 Rotavirus_A R-HSA-373080 Class B/2 (Secretin family receptors) 23/1095 95/10654 6.861876121040217e-5 3.1650720115499153e-4 2.0816178871751445e-4 2788/7476/54331/59345/10681/51764/94235/2642/55970/89780/2792/2793/2785/2783/2641/2784/2782/2786/51384/2791/7976/2790/2787 23 Rotavirus_A R-HSA-167044 Signalling to RAS 9/1095 20/10654 7.273653251850464e-5 3.330427313118344e-4 2.1903694581435176e-4 4893/6464/6714/4914/4803/6654/2885/3845/3265 9 Rotavirus_A R-HSA-381771 Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) 9/1095 20/10654 7.273653251850464e-5 3.330427313118344e-4 2.1903694581435176e-4 2922/1499/51764/338557/60559/2864/2641/2784/9789 9 Rotavirus_A R-HSA-193639 p75NTR signals via NF-kB 8/1095 16/10654 7.339980671367548e-5 3.336354850621613e-4 2.1942679059667203e-4 4804/4790/5584/8878/5970/4792/4803/7189 8 Rotavirus_A R-HSA-418038 Nucleotide-like (purinergic) receptors 8/1095 16/10654 7.339980671367548e-5 3.336354850621613e-4 2.1942679059667203e-4 10161/27334/5032/2840/5028/5031/5029/2846 8 Rotavirus_A R-HSA-381038 XBP1(S) activates chaperone genes 15/1095 50/10654 9.628810610876267e-5 4.360874370867875e-4 2.8680782178086827e-4 10113/10525/1200/6464/9695/37/7094/7494/58477/84447/22872/5611/10130/6745/9820 15 Rotavirus_A R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 7/1095 13/10654 1.1674233347187251e-4 5.193164300350201e-4 3.4154621630092685e-4 2065/207/2064/10000/3084/208/9542 7 Rotavirus_A R-HSA-209560 NF-kB is activated and signals survival 7/1095 13/10654 1.1674233347187251e-4 5.193164300350201e-4 3.4154621630092685e-4 4804/4790/8878/5970/4792/4803/7189 7 Rotavirus_A R-HSA-2995383 Initiation of Nuclear Envelope Reformation 7/1095 13/10654 1.1674233347187251e-4 5.193164300350201e-4 3.4154621630092685e-4 23141/7444/8815/2010/23592/5518/7112 7 Rotavirus_A R-HSA-2995410 Nuclear Envelope Reassembly 7/1095 13/10654 1.1674233347187251e-4 5.193164300350201e-4 3.4154621630092685e-4 23141/7444/8815/2010/23592/5518/7112 7 Rotavirus_A R-HSA-5658623 FGFRL1 modulation of FGFR1 signaling 7/1095 13/10654 1.1674233347187251e-4 5.193164300350201e-4 3.4154621630092685e-4 8074/8817/2249/2248/2247/2255/27006 7 Rotavirus_A R-HSA-6783783 Interleukin-10 signaling 14/1095 47/10654 1.7803899044902495e-4 7.866334280899295e-4 5.173563851269347e-4 3592/1437/3593/3553/941/3383/2357/6774/7132/942/3716/7297/5724/3554 14 Rotavirus_A R-HSA-9609523 Insertion of tail-anchored proteins into the endoplasmic reticulum membrane 9/1095 22/10654 1.7809380811956003e-4 7.866334280899295e-4 5.173563851269347e-4 6811/351/9218/10952/8266/7917/819/2010/224 9 Rotavirus_A R-HSA-168253 Host Interactions with Influenza Factors 13/1095 42/10654 1.968048602075077e-4 0.00086621857485698805 5.696982795480487e-4 3839/3838/55706/7175/9631/79023/57122/23279/3840/8086/7040/6396/55746 13 Rotavirus_A R-HSA-164952 The role of Nef in HIV-1 replication and disease pathogenesis 10/1095 27/10654 2.0707802022876796e-4 9.050612772236363e-4 5.952445115887662e-4 919/920/567/3055/926/2534/3932/375/940/5879 10 Rotavirus_A R-HSA-3000170 Syndecan interactions 10/1095 27/10654 2.0707802022876796e-4 9.050612772236363e-4 5.952445115887662e-4 5578/6383/3688/2247/3690/87/3685/7040/3691/3655 10 Rotavirus_A R-HSA-198323 AKT phosphorylates targets in the cytosol 7/1095 14/10654 2.128010827290641e-4 9.236158104560073e-4 6.074475351293826e-4 842/207/7249/2932/10000/208/4193 7 Rotavirus_A R-HSA-418885 DCC mediated attractive signaling 7/1095 14/10654 2.128010827290641e-4 9.236158104560073e-4 6.074475351293826e-4 9423/5747/4690/6714/2534/998/5879 7 Rotavirus_A R-HSA-2173789 TGF-beta receptor signaling activates SMADs 11/1095 32/10654 2.1608815583663762e-4 9.346373522345917e-4 6.146962291328137e-4 64750/5501/23327/867/7046/4088/9040/4087/7048/7040/5500 11 Rotavirus_A R-HSA-112043 PLC beta mediated events 15/1095 54/10654 2.497779759037953e-4 0.0010766292064818763 7.080820296946067e-4 3838/5331/2770/5578/5330/5573/10768/23236/2771/5332/5580/1385/115/801/2773 15 Rotavirus_A R-HSA-400508 Incretin synthesis, secretion, and inactivation 9/1095 23/10654 2.66080328794928e-4 0.001142956738809828 7.517046004298744e-4 2922/1499/51764/338557/60559/2864/2641/2784/9789 9 Rotavirus_A R-HSA-193704 p75 NTR receptor-mediated signalling 22/1095 97/10654 2.700916609437196e-4 0.001156214301985101 7.604238904003065e-4 4804/57142/4790/5584/57580/8878/7074/10451/23385/5970/4792/9138/4803/3066/3065/7189/6654/7410/7409/387/5879/10672 22 Rotavirus_A R-HSA-112040 G-protein mediated events 15/1095 55/10654 3.1130949839898485e-4 0.0013281121945349183 8.734784201530707e-4 3838/5331/2770/5578/5330/5573/10768/23236/2771/5332/5580/1385/115/801/2773 15 Rotavirus_A R-HSA-170834 Signaling by TGF-beta Receptor Complex 18/1095 73/10654 3.2299586861959473e-4 0.0013732817543350114 9.031857264300162e-4 5590/64750/50848/5501/6667/4609/23327/867/7046/4088/3065/9040/4087/7048/1025/387/7040/5500 18 Rotavirus_A R-HSA-9612973 Autophagy 25/1095 119/10654 3.7752523878230965e-4 0.0015996832151792782 0.0010520863924673822 5563/1915/22863/8878/7249/1080/10013/91782/7416/26100/192111/8655/5289/1457/8678/6714/3320/128866/55054/2475/9804/23710/30849/401505/57521 25 Rotavirus_A R-HSA-159227 Transport of the SLBP independent Mature mRNA 11/1095 34/10654 3.9516218827107127e-4 0.0016687592410095915 0.0010975166039818873 55706/7175/9631/79023/57122/23279/10482/8086/6396/55746/22916 11 Rotavirus_A R-HSA-381119 Unfolded Protein Response (UPR) 21/1095 94/10654 4.583789147907895e-4 0.001929204186829922 0.0012688071325593006 10113/10525/1200/6464/8720/9695/37/7184/7094/7494/811/58477/84447/22872/5611/10130/3309/22926/6745/9451/9820 21 Rotavirus_A R-HSA-73887 Death Receptor Signalling 28/1095 141/10654 4.6009639318549415e-4 0.0019299345351740528 0.0012692874711334192 4804/57142/7186/4790/5584/57580/356/9530/8878/7074/355/10451/23385/5970/4792/7132/9138/4803/3066/3065/7189/6654/7410/7409/387/8743/5879/10672 28 Rotavirus_A R-HSA-168276 NS1 Mediated Effects on Host Pathways 12/1095 40/10654 4.755132307203113e-4 0.0019879315665564854 0.0013074312029310445 3839/3838/55706/7175/9631/79023/57122/23279/3840/8086/6396/55746 12 Rotavirus_A R-HSA-8876384 Listeria monocytogenes entry into host cells 8/1095 20/10654 4.9336154834315e-4 0.0020556731180964584 0.0013519837517754394 1499/1500/4233/6714/867/999/30011/2885 8 Rotavirus_A R-HSA-8957275 Post-translational protein phosphorylation 23/1095 108/10654 5.202689545031305e-4 0.0021605853592322694 0.0014209828762613917 351/8720/7018/10618/7184/8074/6383/3912/348/3827/338/5589/5611/197/10130/5265/3895/375056/1000/5954/10970/5034/2519 23 Rotavirus_A R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 11/1095 35/10654 5.234108438822058e-4 0.0021664356120952226 0.0014248304951969427 55706/7175/9631/79023/57122/23279/10482/8086/6396/55746/22916 11 Rotavirus_A R-HSA-1632852 Macroautophagy 21/1095 95/10654 5.326669394120373e-4 0.0021974708721618705 0.0014452418957123542 5563/22863/8878/7249/91782/7416/26100/192111/8655/5289/1457/8678/6714/128866/55054/2475/9804/23710/30849/401505/57521 21 Rotavirus_A R-HSA-8854691 Interleukin-20 family signaling 9/1095 25/10654 5.50344542508586e-4 0.0022629298622885937 0.0014882932399556984 11009/6774/3718/6772/3717/3716/53832/7297/5781 9 Rotavirus_A R-HSA-6804758 Regulation of TP53 Activity through Acetylation 10/1095 30/10654 5.535550828912052e-4 0.0022686683725049394 0.001492067367516933 5305/207/79837/1108/10000/3066/3065/7157/208/8396 10 Rotavirus_A R-HSA-381033 ATF6 (ATF6-alpha) activates chaperones 6/1095 12/10654 6.221550661073489e-4 0.0025414831131836146 0.001671493314860129 8720/7184/7494/811/3309/22926 6 Rotavirus_A R-HSA-6804757 Regulation of TP53 Degradation 11/1095 36/10654 6.846304788528273e-4 0.002787583382951251 0.0018333495764925704 5170/1029/6446/207/1616/10000/7157/208/2475/5518/4193 11 Rotavirus_A R-HSA-5621575 CD209 (DC-SIGN) signaling 8/1095 21/10654 7.257486391594226e-4 0.002945408438147007 0.0019371486233202633 4893/4790/5970/4067/2534/5894/3845/3265 8 Rotavirus_A R-HSA-2173788 Downregulation of TGF-beta receptor signaling 9/1095 26/10654 7.65735052801877e-4 0.003097633708745457 0.0020372647802359596 64750/5501/23327/7046/4088/4087/7048/7040/5500 9 Rotavirus_A R-HSA-375280 Amine ligand-binding receptors 12/1095 42/10654 7.756760101868342e-4 0.0031277258475275573 0.0020570559047739137 146/3356/3357/1128/148/1131/3358/1133/3269/4935/147/154 12 Rotavirus_A R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 25/1095 125/10654 8.142552743756779e-4 0.00327273020247459 0.0021524229794801304 351/8720/7018/10618/7184/8074/6383/3912/348/3827/338/5589/5611/197/10130/5265/3895/375056/1000/5954/3479/10970/2147/5034/2519 25 Rotavirus_A R-HSA-6806003 Regulation of TP53 Expression and Degradation 11/1095 37/10654 8.850682260497381e-4 0.003545946418468502 0.002332112970799074 5170/1029/6446/207/1616/10000/7157/208/2475/5518/4193 11 Rotavirus_A R-HSA-6798695 Neutrophil degranulation 71/1095 480/10654 9.473636764772385e-4 0.0037834012638867354 0.002488283273343613 10450/5869/2717/2512/2934/5777/10890/4893/9218/4790/83858/7305/10159/1938/1915/3107/2358/5175/1650/23197/823/3163/2268/2215/5908/7414/258010/23385/55754/2357/25852/2896/5611/8655/84061/1315/567/7415/3106/5701/9342/197/2821/5265/55832/3320/158747/1/3482/391/3728/10075/5580/6709/10857/10097/3916/3685/8826/5906/387/81619/196527/2212/8987/10970/2990/2207/5724/2519/5879 71 Rotavirus_A R-HSA-5628897 TP53 Regulates Metabolic Genes 19/1095 86/10654 9.701116896696699e-4 0.0038619095926340358 0.002539916961555522 5563/207/1345/7249/7533/7534/1351/1350/2821/10000/10128/5728/7157/208/2475/1327/4697/9167/57521 19 Rotavirus_A R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 8/1095 22/10654 0.0010386942568964873 0.0041087589275968645 0.002702265871539496 351/994/2309/356/823/2801/993/1020 8 Rotavirus_A R-HSA-8863678 Neurodegenerative Diseases 8/1095 22/10654 0.0010386942568964873 0.0041087589275968645 0.002702265871539496 351/994/2309/356/823/2801/993/1020 8 Rotavirus_A R-HSA-3232142 SUMOylation of ubiquitinylation proteins 11/1095 38/10654 0.0011316978543852879 0.00446253097155082 0.0029349361589736337 55706/7175/9631/79023/57122/23279/7341/8086/6396/55746/4193 11 Rotavirus_C R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 296/1879 309/10654 3.975326154953165e-211 4.977108346001362e-208 2.606977046879812e-208 8454/9354/57154/5718/197131/23352/5689/26224/8945/10293/51088/140460/5684/79754/6737/8065/64410/127544/114088/5720/11065/285231/221687/9666/84937/57531/142678/55070/5682/84708/246184/146330/55819/51320/93611/54850/7319/142686/8916/79791/26046/151636/5700/122706/7321/5707/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/8697/7320/5690/26235/10477/9817/10193/148581/9039/223082/92912/154881/5717/140739/25897/9491/6500/23198/6478/150726/390594/10533/81559/144699/143471/5706/140462/5705/26259/57674/51130/10197/53339/154214/7336/200845/79876/26263/64750/51619/6477/9690/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/10213/5709/9604/9978/22888/5695/23304/7317/80196/114907/140456/64718/54926/4008/7335/84861/11059/55236/84085/55958/54620/4734/84078/7337/5714/26272/84676/140691/27252/51444/7704/8651/3093/26118/222235/51433/9861/25831/7322/5715/64219/10489/5711/23327/9867/26249/140458/55905/5701/5688/55336/5687/26270/143279/51465/63893/89122/6502/23291/118424/5685/10616/5683/5698/5708/27246/5692/5686/89910/5713/55521/25898/9903/201456/55294/5699/26190/55008/7328/79654/5710/10422/84727/135892/7428/5702/22954/8453/401036/83737/51529/9040/90933/140461/7324/63891/5719/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/5704/6233/90135/56658/9870/9520/51434/6468/26267/142685/5716/25847/90025/7327/10425/25793/51343/7311/26091/23295/6047/84541/7318/23194/51666/90293/131405/55175/55284/868/54461/9320/136371/80204/26232/29882/57520/26234/127247/27338/7334/92591/5930/11275/55182/5694/84961/4591/23014/29116/26268/92369/115290/90678/51725/140459/5693/5721/5696/997/23608/51676/55585/64320/5691/51132/84261/7325/57542/9820/55658/7314/996/10324/283807/899 296 Rotavirus_C R-HSA-983169 Class I MHC mediated antigen processing & presentation 308/1879 371/10654 8.054579105051993e-175 5.042166519762548e-172 2.641054096024943e-172 8454/9354/57154/1147/5718/197131/23352/5689/26224/8945/10293/51088/140460/5684/79754/6737/8065/64410/127544/114088/5720/11065/285231/221687/9666/84937/57531/142678/55070/5682/84708/246184/146330/55819/51320/93611/54850/7319/142686/8916/79791/26046/151636/5700/122706/7321/5707/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/8697/10484/7320/5690/26235/10477/10802/9817/10193/148581/9039/223082/92912/154881/5717/140739/821/25897/9491/6500/23198/6478/150726/390594/10533/81559/144699/143471/5706/140462/5705/26259/57674/51130/10197/53339/8517/154214/7336/200845/79876/26263/64750/51619/6477/9690/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/10213/5709/9604/9978/22888/5695/23304/7317/80196/114907/140456/22872/64718/54926/4008/7335/84861/11059/55236/84085/55958/54620/4734/84078/7337/5714/26272/84676/140691/27252/51444/7704/8651/3093/26118/222235/51433/9861/25831/7322/5715/64219/10489/5711/23327/9867/26249/140458/55905/5701/5688/55336/5687/26270/143279/51465/63893/89122/6502/23291/118424/5685/10616/5683/3309/5698/5708/27246/5692/5686/89910/5713/55521/25898/9903/201456/55294/5699/26190/55008/7328/79654/5710/10422/84727/135892/9632/7428/5702/22954/8453/401036/83737/51529/9040/90933/140461/7324/63891/5719/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/5704/6233/90135/56658/9870/9520/51434/6468/26267/142685/5716/25847/90025/7327/10425/25793/51343/7311/26091/23295/6047/84541/7318/23194/51666/90293/131405/55175/55284/868/54461/9320/136371/80204/26232/29882/57520/26234/6396/127247/27338/7334/92591/5930/11275/55182/5694/7097/84961/4591/3551/23014/29116/26268/92369/115290/90678/51725/140459/5693/5721/5696/997/23608/51676/55585/64320/5691/51132/84261/7325/10427/57542/9820/55658/7314/996/10324/283807/899 308 Rotavirus_C R-HSA-8951664 Neddylation 211/1879 234/10654 2.7665875035896333e-134 1.154589184831407e-131 6.047663209601199e-132 8454/9318/5718/51397/5689/26224/54165/8945/56995/23412/51088/9655/140460/5684/79754/8065/64410/5720/149951/29099/285231/11091/5682/23038/64344/146330/93611/54850/142686/55884/79791/5700/122706/7321/5707/51665/9616/122769/9021/4738/5690/26235/9817/9039/154881/5717/140739/5929/9491/6500/23198/5931/150726/3091/390594/144699/143471/5706/140462/28952/5705/26259/51130/10197/53339/28991/200845/332/26263/140825/8452/8450/7323/9306/10517/89890/142689/7316/10213/5709/50717/9978/5695/114907/140456/4008/84861/64708/84085/55958/54620/84078/5714/55527/26272/27252/7704/1643/26118/222235/10980/9861/7322/5715/122416/10489/5711/26249/140458/5701/5688/55336/5687/26270/1161/6502/23291/170622/5685/90864/5683/55832/5698/5708/1642/5692/10920/5686/5713/9903/201456/55294/5699/26190/10238/5710/84727/10987/7428/5702/8453/123879/401036/9040/140461/5719/79176/80176/8139/23142/126433/10116/5704/26043/6233/90135/6468/2873/26267/142685/5716/25793/7311/1154/84541/23194/51666/2034/90293/55175/8533/54461/136371/80204/26232/8835/26234/127247/8883/92591/11275/5694/51122/84961/54939/23014/26268/92369/115290/54951/51725/140459/5693/55208/5721/84259/5696/51676/5691/84261/150684/50813/57542/9820/7314/51138/10324/8451/56929/283807/899 211 Rotavirus_C R-HSA-5663205 Infectious disease 232/1879 383/10654 4.5450804108502675e-82 1.4226101685961336e-79 7.45153972620978e-80 60489/3839/5718/23165/3303/5689/6138/8945/1173/6144/2963/3837/3838/6917/6203/5434/5440/5684/5903/6227/9349/8065/4736/2926/5720/902/6206/6194/6234/6191/55706/7175/162/6128/5682/51121/6132/9631/1499/1938/6147/6129/6217/5700/3843/122706/5707/5430/6222/5436/6176/6152/5690/6136/2060/1174/7520/8106/3841/6125/5717/4869/821/9491/6500/23198/404672/6749/6224/6146/348995/6141/10015/143471/6202/79023/5706/57122/5705/5441/23636/10197/6232/5438/6134/6169/10762/5431/6160/7469/23511/5435/4686/7316/6155/10213/5709/1500/6175/9978/293/5433/6218/5695/53371/5611/292/4331/6209/5714/6193/23279/6210/4927/6229/9688/11224/8148/6205/2966/6165/8731/9861/79902/6130/9150/5715/9525/2962/3840/5711/6204/23327/9883/5701/867/5688/6228/5437/8812/23521/5687/23225/5685/5683/5698/5708/3320/8815/5692/2965/5686/5713/6156/5699/905/6143/5710/2068/6181/5439/6124/5702/2071/5901/6207/8086/5478/5719/3836/6827/6139/5704/6233/2885/3326/2968/5716/7514/163/1025/7311/6223/25873/9972/6881/2967/51616/1213/5610/6908/1211/3921/6188/6189/8021/808/11198/6396/6135/6201/129401/904/5694/7936/3304/6829/1104/51497/801/9045/6187/1022/5432/55746/6168/22916/5693/6208/5721/6137/5696/8178/5691/8480/6122/6877/6133/7314/805/25920/6230 232 Rotavirus_C R-HSA-168254 Influenza Infection 125/1879 155/10654 8.165030434717325e-67 2.0445236208532183e-64 1.070908202279767e-64 3839/23165/3303/6138/6144/2963/3837/3838/6203/5434/5440/5903/6227/9349/4736/2926/6206/6194/6234/6191/55706/7175/6128/51121/6132/9631/6147/6129/6217/3843/5430/6222/5436/6176/6152/6136/8106/3841/6125/821/6224/6146/348995/6141/6202/79023/57122/5441/23636/6232/5438/6134/6169/10762/5431/6160/23511/5435/6155/6175/293/5433/6218/53371/5611/6209/6193/23279/6210/4927/6229/9688/11224/6205/6165/79902/6130/2962/3840/6204/9883/6228/5437/23521/23225/3320/6156/6143/6181/5439/6124/5901/6207/8086/3836/6139/6233/7514/7311/6223/25873/9972/1213/5610/1211/3921/6188/6189/8021/6396/6135/6201/129401/3304/9045/6187/5432/55746/6168/6208/6137/8480/6122/6133/6230 125 Rotavirus_C R-HSA-2262752 Cellular responses to stress 243/1879 479/10654 1.1428610180386643e-64 2.3847699909740126e-62 1.2491270425229611e-62 1912/5718/23165/818/3303/7014/6118/5689/3725/84617/6782/25913/1019/5684/5903/5720/11065/573/4790/55706/7175/5241/5682/64344/9631/246184/112399/7531/7290/1915/1783/5700/122706/116835/7321/5707/2146/10111/25828/8535/84962/6045/7422/8697/5690/10382/57690/9530/3308/5717/9491/23198/27327/80012/898/10049/5931/10294/5925/3091/7013/7277/348995/10013/143471/545/79023/5706/472/10381/57122/5705/23636/79813/10197/3337/192670/7278/3313/10808/1780/10762/8881/29855/23511/7323/4306/1781/7316/10213/5709/9978/5695/10935/3305/53371/5970/1639/9261/1911/9532/26277/5714/2289/23279/4927/9688/10121/7415/6647/7867/8994/51433/9861/79902/7322/91582/5715/6119/5711/9883/5928/1432/2932/5701/10524/5688/1387/84733/4683/5687/57805/7846/259217/112398/23225/3310/113457/2908/5685/5683/3309/5698/347733/5708/3320/5692/65057/5686/5713/2033/23512/7266/57332/5699/5710/6767/25842/126374/51143/3301/7428/5702/192669/10540/9531/7157/81027/8453/51529/8086/23135/7324/10963/5719/4001/64682/29945/10393/22824/57600/23112/5704/6233/51434/3326/5716/3306/27000/2353/51343/7311/367/9972/2034/57634/10383/23411/84790/8021/9529/4343/8726/55662/29882/6396/648/129401/5600/54583/5694/3304/3312/523/201163/23466/4217/26523/5052/405/54386/96459/3297/55746/5693/5721/55466/5696/7280/2288/5691/5034/8480/10919/10728/829/7314/996/51182/6015/4193/2950/1778 243 Rotavirus_C R-HSA-168255 Influenza Life Cycle 118/1879 144/10654 1.409744582702406e-64 2.521428882204875e-62 1.320708082742254e-62 23165/3303/6138/6144/2963/3837/6203/5434/5440/5903/6227/9349/4736/2926/6206/6194/6234/6191/55706/7175/6128/51121/6132/9631/6147/6129/6217/3843/5430/6222/5436/6176/6152/6136/6125/821/6224/6146/348995/6141/6202/79023/57122/5441/23636/6232/5438/6134/6169/10762/5431/6160/23511/5435/6155/6175/5433/6218/53371/5611/6209/6193/23279/6210/4927/6229/9688/11224/6205/6165/79902/6130/2962/6204/9883/6228/5437/23521/23225/3320/6156/6143/6181/5439/6124/5901/6207/8086/3836/6139/6233/7514/7311/6223/25873/9972/1213/1211/3921/6188/6189/8021/6396/6135/6201/129401/3304/9045/6187/5432/55746/6168/6208/6137/8480/6122/6133/6230 118 Rotavirus_C R-HSA-8953897 Cellular responses to external stimuli 243/1879 493/10654 1.608094719611863e-61 2.5166682361925656e-59 1.318214487260777e-59 1912/5718/23165/818/3303/7014/6118/5689/3725/84617/6782/25913/1019/5684/5903/5720/11065/573/4790/55706/7175/5241/5682/64344/9631/246184/112399/7531/7290/1915/1783/5700/122706/116835/7321/5707/2146/10111/25828/8535/84962/6045/7422/8697/5690/10382/57690/9530/3308/5717/9491/23198/27327/80012/898/10049/5931/10294/5925/3091/7013/7277/348995/10013/143471/545/79023/5706/472/10381/57122/5705/23636/79813/10197/3337/192670/7278/3313/10808/1780/10762/8881/29855/23511/7323/4306/1781/7316/10213/5709/9978/5695/10935/3305/53371/5970/1639/9261/1911/9532/26277/5714/2289/23279/4927/9688/10121/7415/6647/7867/8994/51433/9861/79902/7322/91582/5715/6119/5711/9883/5928/1432/2932/5701/10524/5688/1387/84733/4683/5687/57805/7846/259217/112398/23225/3310/113457/2908/5685/5683/3309/5698/347733/5708/3320/5692/65057/5686/5713/2033/23512/7266/57332/5699/5710/6767/25842/126374/51143/3301/7428/5702/192669/10540/9531/7157/81027/8453/51529/8086/23135/7324/10963/5719/4001/64682/29945/10393/22824/57600/23112/5704/6233/51434/3326/5716/3306/27000/2353/51343/7311/367/9972/2034/57634/10383/23411/84790/8021/9529/4343/8726/55662/29882/6396/648/129401/5600/54583/5694/3304/3312/523/201163/23466/4217/26523/5052/405/54386/96459/3297/55746/5693/5721/55466/5696/7280/2288/5691/5034/8480/10919/10728/829/7314/996/51182/6015/4193/2950/1778 243 Rotavirus_C R-HSA-168273 Influenza Viral RNA Transcription and Replication 109/1879 134/10654 4.838534737577075e-59 6.730939434940554e-57 3.525622387731599e-57 23165/6138/6144/2963/6203/5434/5440/5903/6227/9349/4736/2926/6206/6194/6234/6191/55706/7175/6128/51121/6132/9631/6147/6129/6217/3843/5430/6222/5436/6176/6152/6136/6125/6224/6146/348995/6141/6202/79023/57122/5441/23636/6232/5438/6134/6169/10762/5431/6160/23511/5435/6155/6175/5433/6218/53371/5611/6209/6193/23279/6210/4927/6229/9688/11224/6205/6165/79902/6130/2962/6204/9883/6228/5437/23521/23225/3320/6156/6143/6181/5439/6124/6207/8086/6139/6233/7311/6223/25873/9972/3921/6188/6189/8021/6396/6135/6201/129401/9045/6187/5432/55746/6168/6208/6137/8480/6122/6133/6230 109 Rotavirus_C R-HSA-9010553 Regulation of expression of SLITs and ROBOs 125/1879 171/10654 5.612563102856922e-58 7.026929004776866e-56 3.6806598032419603e-56 10921/5718/5689/6138/6144/23032/6203/5684/6227/9349/4736/5720/6206/6194/6234/6191/6128/5682/51121/6132/6147/6129/6217/5700/122706/5707/6222/6176/6152/5690/6136/6125/5717/9491/23198/6224/6146/6141/26986/23053/143471/6202/5706/5705/10197/6232/6134/6169/6160/4686/7316/6155/10213/5709/6175/9978/6218/5695/4116/6209/5714/6193/6210/6229/11224/6205/6165/9861/6130/5715/5711/6204/5701/5688/6228/23521/5687/5685/5683/5698/5708/5692/5686/5713/3199/1981/6156/5699/6143/5710/6181/6124/5702/8453/6207/5719/6139/5704/6233/5716/7311/6223/25873/3921/6188/6189/9775/6135/6201/5694/9045/6187/6168/22916/5693/6208/5721/6137/5696/5691/4440/6122/6133/7314/6230 125 Rotavirus_C R-HSA-2555396 Mitotic Metaphase and Anaphase 134/1879 202/10654 5.709269115035225e-54 6.4981863018400924e-52 3.40370780733679e-52 4000/5718/5689/55839/84617/26271/79682/5684/5903/5720/11065/54908/55143/5682/246184/55869/1783/1058/5700/122706/7321/5707/991/401541/79019/80152/8697/5690/10382/9212/5717/3619/9491/23198/79172/10274/7277/348995/23421/143471/79023/5706/10381/57122/5705/64105/10735/10197/7278/6232/332/7443/1780/8881/5885/1781/7316/10213/5709/5695/5501/4085/5714/23279/55166/51433/9861/79902/5715/54821/5519/5711/5701/2491/5688/699/5687/7846/113457/5685/5683/5698/347733/5708/8815/5692/5686/5713/1060/91687/8243/9126/5699/5529/5710/51143/5702/5520/81027/51529/7324/2010/5719/4001/64682/29945/10393/5704/6233/51434/5716/7514/7311/9184/5518/10383/5347/84790/29882/6396/5694/64946/10726/55746/7112/5693/5721/5696/7280/5691/7314/996/5515/1778 134 Rotavirus_C R-HSA-68882 Mitotic Anaphase 133/1879 201/10654 2.26944861993114e-53 2.3677913934614896e-51 1.2402337633483337e-51 4000/5718/5689/55839/84617/79682/5684/5903/5720/11065/54908/55143/5682/246184/55869/1783/1058/5700/122706/7321/5707/991/401541/79019/80152/8697/5690/10382/9212/5717/3619/9491/23198/79172/10274/7277/348995/23421/143471/79023/5706/10381/57122/5705/64105/10735/10197/7278/6232/332/7443/1780/8881/5885/1781/7316/10213/5709/5695/5501/4085/5714/23279/55166/51433/9861/79902/5715/54821/5519/5711/5701/2491/5688/699/5687/7846/113457/5685/5683/5698/347733/5708/8815/5692/5686/5713/1060/91687/8243/9126/5699/5529/5710/51143/5702/5520/81027/51529/7324/2010/5719/4001/64682/29945/10393/5704/6233/51434/5716/7514/7311/9184/5518/10383/5347/84790/29882/6396/5694/64946/10726/55746/7112/5693/5721/5696/7280/5691/7314/996/5515/1778 133 Rotavirus_C R-HSA-162906 HIV Infection 143/1879 233/10654 2.767355380200207e-51 2.665176104623584e-49 1.39600194482974e-49 60489/5718/23165/5689/8945/1173/2963/3837/6917/5434/5440/5684/5903/8065/5720/902/55706/7175/162/5682/9631/5700/122706/5707/5430/5436/5690/1174/7520/5717/4869/9491/6500/23198/404672/6749/348995/10015/143471/79023/5706/57122/5705/5441/23636/10197/5438/10762/5431/7469/23511/5435/4686/7316/10213/5709/9978/293/5433/5695/53371/292/4331/5714/23279/4927/9688/8148/2966/8731/9861/79902/9150/5715/9525/2962/5711/23327/9883/5701/5688/5437/8812/5687/23225/5685/5683/5698/5708/8815/5692/2965/5686/5713/5699/905/5710/2068/5439/5702/2071/5901/8086/5478/5719/3836/6827/5704/6233/2968/5716/7514/163/1025/7311/9972/6881/2967/51616/6908/8021/11198/6396/129401/904/5694/7936/6829/1104/51497/1022/5432/55746/22916/5693/5721/5696/8178/5691/8480/6877/7314/25920 143 Rotavirus_C R-HSA-2467813 Separation of Sister Chromatids 126/1879 190/10654 9.615898483700377e-51 8.599360643994908e-49 4.5042892897333344e-49 5718/5689/55839/84617/79682/5684/5903/5720/11065/54908/55143/5682/246184/55869/1783/1058/5700/122706/7321/5707/991/401541/79019/80152/8697/5690/10382/9212/5717/3619/9491/23198/79172/10274/7277/348995/23421/143471/79023/5706/10381/57122/5705/64105/10735/10197/7278/6232/332/1780/8881/5885/1781/7316/10213/5709/5695/5501/4085/5714/23279/55166/51433/9861/79902/5715/54821/5519/5711/5701/2491/5688/699/5687/7846/113457/5685/5683/5698/347733/5708/5692/5686/5713/1060/91687/8243/9126/5699/5529/5710/51143/5702/81027/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/7514/7311/9184/5518/10383/5347/84790/29882/6396/5694/64946/10726/55746/5693/5721/5696/7280/5691/7314/996/5515/1778 126 Rotavirus_C R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 77/1879 86/10654 2.2410961206759504e-48 1.753657714428931e-46 9.185545284086297e-47 8454/5718/5689/8945/26271/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/9212/5717/9491/6500/23198/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/4085/983/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/51529/7324/5719/64682/29945/10393/4751/5704/6233/51434/5716/51343/7311/9184/5347/29882/5694/5693/5721/5696/5691/7314/996 77 Rotavirus_C R-HSA-453276 Regulation of mitotic cell cycle 77/1879 86/10654 2.2410961206759504e-48 1.753657714428931e-46 9.185545284086297e-47 8454/5718/5689/8945/26271/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/9212/5717/9491/6500/23198/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/4085/983/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/51529/7324/5719/64682/29945/10393/4751/5704/6233/51434/5716/51343/7311/9184/5347/29882/5694/5693/5721/5696/5691/7314/996 77 Rotavirus_C R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 73/1879 80/10654 2.639871800381166e-47 1.944187937692482e-45 1.0183530226857377e-45 8454/5718/5689/8945/26271/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/6500/23198/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/9184/5347/29882/5694/5693/5721/5696/5691/7314/996 73 Rotavirus_C R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 68/1879 72/10654 1.0181864677365784e-46 7.082052542256645e-45 3.709533154385312e-45 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/9212/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/5347/29882/5694/5693/5721/5696/5691/7314/996 68 Rotavirus_C R-HSA-68886 M Phase 188/1879 395/10654 1.7524407891659834e-44 1.1547662463346374e-42 6.048590646262646e-43 4000/5718/23165/5689/55839/84617/26271/79682/5684/5903/5720/11065/54908/55706/7175/55143/5682/64151/22981/9631/246184/7531/55869/1783/1058/5700/11190/122706/7321/5707/991/401541/203068/79019/7532/1454/80152/8697/5690/10382/9212/5717/3619/9491/23198/79172/10274/5925/121441/7277/348995/23421/143471/79023/5706/10381/57122/5705/23636/64105/10735/23310/10197/7278/6232/332/7443/1780/10762/8881/10051/5885/23511/1781/7316/10213/5709/891/5695/5501/53371/26003/4085/983/1639/5714/23279/4927/9688/55166/10121/51433/9861/79902/9702/5566/5715/54821/5519/5711/9883/5701/2491/5688/10112/699/5687/7846/23225/113457/5685/7283/5683/5698/347733/5708/3320/8815/5692/5686/5713/80097/1060/91687/8243/9126/10426/5699/23397/5529/5710/9663/11064/51143/5702/10540/5520/81027/10733/51529/85378/8086/7324/2010/5719/4001/64682/29945/10393/79648/4751/5704/6233/23175/51434/5716/7514/7311/9184/9972/5518/10383/5347/54892/84790/8021/29882/6396/129401/5694/1453/27229/64946/10726/55746/7112/5693/5721/5696/10592/7280/5691/29781/8480/7314/996/5515/1778 188 Rotavirus_C R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 69/1879 76/10654 2.1276320643114248e-44 1.331897672258952e-42 6.976393558242198e-43 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/51529/7324/5719/64682/29945/10393/4751/5704/6233/51434/5716/7311/9184/5347/29882/5694/5693/5721/5696/5691/7314/996 69 Rotavirus_C R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 63/1879 66/10654 3.6895908366355117e-44 2.1996989178417432e-42 1.1521880156510897e-42 5718/5689/5684/5720/5682/64344/112399/5700/122706/7321/5707/84962/5690/5717/9491/23198/3091/143471/5706/5705/10197/7323/7316/10213/5709/9978/5695/5714/8994/9861/7322/5715/5711/5701/5688/5687/112398/5685/5683/5698/5708/5692/5686/5713/5699/5710/126374/7428/5702/8453/5719/5704/6233/5716/7311/2034/54583/5694/5693/5721/5696/5691/7314 63 Rotavirus_C R-HSA-69620 Cell Cycle Checkpoints 155/1879 293/10654 5.730577113407698e-44 3.261219339084744e-42 1.7082055223220077e-42 5718/4172/6118/5689/55839/79682/5684/5903/5720/11065/54908/8318/55143/5682/246184/7531/1783/1058/5700/122706/7321/5707/991/401541/79019/10111/7532/10971/80152/8697/5690/9212/51720/5717/3619/5982/9491/23198/63967/79172/898/7533/348995/23421/4173/143471/545/79023/5706/472/57122/5705/64105/10197/7336/6232/7534/332/580/1780/8881/29086/1781/7316/10213/5709/4174/891/993/5695/5501/4085/983/641/5714/4171/23279/55166/51433/9861/79902/5715/54821/9656/5519/4998/6119/5711/5701/10524/2491/5688/4683/699/5687/5685/5683/5698/5708/5692/5985/5686/5713/1060/91687/165918/5699/5529/4175/5710/51143/1111/5702/7157/51529/7324/5719/64682/29945/10393/8924/5704/6233/51434/5716/672/7514/5932/7158/7311/9184/9025/79184/5518/5347/29882/6396/7334/5694/7465/64946/10726/55746/5693/5721/5696/83695/5691/4176/7529/7314/996/4193/5515/1778 155 Rotavirus_C R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 67/1879 73/10654 6.801612398253322e-44 3.7024429228752866e-42 1.93931557167589e-42 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/51529/7324/5719/64682/29945/10393/4751/5704/6233/51434/5716/7311/9184/29882/5694/5693/5721/5696/5691/7314/996 67 Rotavirus_C R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 59/1879 60/10654 8.062466680020835e-44 4.2059201180775356e-42 2.203033658619728e-42 8454/1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/9039/5717/9491/6500/23198/143471/5706/5705/10197/7316/10213/5709/5695/9020/5970/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5971/5694/5693/5721/5696/5691/4791/7314 59 Rotavirus_C R-HSA-376176 Signaling by ROBO receptors 129/1879 218/10654 8.638820078626247e-44 4.3263210953760243e-42 2.2660989090459585e-42 10921/5718/5689/6138/6144/23032/6203/5684/6227/9349/4736/5720/6206/6194/6234/6191/6128/5682/51121/6132/6147/6129/6217/5700/122706/5707/6222/6176/6152/5690/6136/6125/5717/9491/23198/6224/6146/6141/26986/23053/143471/6202/5706/5705/10197/6232/6134/6169/6160/4686/7316/6155/10213/5709/6175/9978/6218/5695/4116/5216/6209/5714/6193/6210/6229/11224/6205/6165/9861/5566/6130/5715/5711/6204/5701/5688/6228/23521/5687/5685/5683/5698/5708/5692/5686/5713/3199/1981/6156/5699/6143/5710/6181/6124/5702/998/8453/6207/5719/6139/5704/6233/5716/7311/6223/25873/387/3921/6188/6189/9775/6135/6201/5694/9045/6187/6168/22916/5693/6208/5721/6137/5696/5691/4440/6122/6133/7314/6230 129 Rotavirus_C R-HSA-1234174 Cellular response to hypoxia 68/1879 75/10654 1.1287429365615958e-43 5.234022802130067e-42 2.7415471714537006e-42 5718/5689/5684/5720/5682/64344/112399/5700/122706/7321/5707/84962/7422/5690/5717/9491/23198/3091/143471/5706/5705/10197/7323/7316/10213/5709/9978/5695/5714/8994/9861/7322/5715/5711/5701/5688/1387/5687/112398/5685/5683/5698/5708/5692/5686/5713/2033/5699/5710/126374/7428/5702/8453/5719/5704/6233/5716/7311/2034/55662/54583/5694/405/5693/5721/5696/5691/7314 68 Rotavirus_C R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 68/1879 75/10654 1.1287429365615958e-43 5.234022802130067e-42 2.7415471714537006e-42 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/51529/7324/5719/64682/29945/10393/4751/5704/6233/51434/5716/7311/9184/29882/5694/5693/5721/5696/5691/7314/996 68 Rotavirus_C R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 138/1879 244/10654 1.2442793741395877e-43 5.563706344367014e-42 2.914233271011139e-42 7536/10921/23165/22827/23451/53981/2963/6635/5434/5440/5903/6633/220988/8683/6430/6632/6627/55706/7175/9631/27339/11051/55696/23350/5430/4904/5436/9879/6428/9128/3184/8106/29894/3178/6637/23450/348995/79023/57122/5441/23636/3183/5438/10762/5431/9092/5093/23511/5435/10594/4686/9785/6625/5433/53371/11338/1655/9343/3185/4116/3190/1477/6626/56339/7307/6429/23279/10181/4927/9688/79902/2962/22938/988/9883/51213/10236/5437/10250/6629/4670/23020/23225/10189/6434/9295/10465/6631/10482/10949/55660/3181/5439/10421/1660/23283/8086/2521/3191/10285/57721/27316/6636/3187/1993/1665/9972/23524/56949/6634/5094/51593/8021/9775/3192/6396/129401/6427/3312/8175/5356/6426/57461/3188/84991/10291/5432/55746/22916/5725/1479/26121/11100/8480/10992/10262/6628/1994 138 Rotavirus_C R-HSA-162909 Host Interactions of HIV factors 94/1879 129/10654 1.4948120471174556e-43 6.453464424107084e-42 3.380282778055081e-42 60489/5718/23165/5689/8945/1173/3837/5684/5903/8065/5720/55706/7175/162/5682/9631/5700/122706/5707/5690/1174/5717/4869/9491/6500/23198/348995/143471/79023/5706/57122/5705/23636/10197/10762/23511/7316/10213/5709/9978/293/5695/53371/292/5714/23279/4927/9688/9861/79902/5715/5711/9883/5701/5688/5687/23225/5685/5683/5698/5708/8815/5692/5686/5713/5699/5710/5702/5901/8086/5478/5719/3836/5704/6233/5716/7514/163/1025/7311/9972/8021/6396/129401/904/5694/1104/55746/5693/5721/5696/5691/8480/7314 94 Rotavirus_C R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 66/1879 72/10654 3.644666573245683e-43 1.5210408499011985e-41 7.967113246077406e-42 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/7311/9184/29882/5694/5693/5721/5696/5691/7314/996 66 Rotavirus_C R-HSA-5676590 NIK-->noncanonical NF-kB signaling 58/1879 59/10654 4.613025996057329e-43 1.8630672732463794e-41 9.758625451761345e-42 8454/1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/9039/5717/9491/6500/23198/143471/5706/5705/10197/7316/10213/5709/5695/9020/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5971/5694/5693/5721/5696/5691/4791/7314 58 Rotavirus_C R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 63/1879 67/10654 5.1368151237615456e-43 2.0097789171717047e-41 1.0527091520077115e-41 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/7311/29882/5694/5693/5721/5696/5691/7314/996 63 Rotavirus_C R-HSA-69052 Switching of origins to a post-replicative state 75/1879 90/10654 2.5370895656507097e-42 9.625564049074814e-41 5.041807972569033e-41 8454/5718/4172/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/5717/9491/6500/23198/898/4173/143471/5706/5705/10197/8881/7316/10213/5709/9978/4174/5695/5714/4171/51433/9861/5715/4998/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/5699/4175/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/29882/5694/5693/5721/5696/5691/4176/7314/996 75 Rotavirus_C R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 60/1879 63/10654 6.331761846881937e-42 2.331578185969466e-40 1.221265520311903e-40 5718/5689/5684/5720/11065/5682/246184/5700/7321/5707/8697/5690/5717/9491/5706/5705/10197/8881/7316/10213/5709/5695/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/29882/5694/5693/5721/5696/5691/7314/996 60 Rotavirus_C R-HSA-1169091 Activation of NF-kappaB in B cells 62/1879 67/10654 3.135423161645795e-41 1.121585656680153e-39 5.874792871294226e-40 8454/1147/5718/5689/8945/5684/5720/4790/6885/5966/5682/5700/122706/5707/5690/5717/9491/6500/23198/143471/5706/5705/10197/8517/7316/10213/5709/5695/5970/4792/4793/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/4794/5694/3551/5693/5721/5696/5691/7314 62 Rotavirus_C R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 55/1879 56/10654 8.601912515485521e-41 2.991554019274409e-39 1.5669565781132983e-39 5718/3303/5689/5684/5720/5682/5700/122706/5707/5690/3184/5717/9491/3315/23198/26986/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/1981/5699/5710/5702/5719/5704/6233/5716/7311/5694/3304/3312/5693/5721/5696/5691/7314 55 Rotavirus_C R-HSA-6807070 PTEN Regulation 96/1879 140/10654 9.494343173233094e-41 3.212680446726441e-39 1.6827811655545425e-39 1912/5718/5689/27161/3725/5684/8841/5720/5682/5468/23186/5700/122706/5707/2146/5978/9112/9219/8535/10273/51564/6045/5690/57690/5717/9491/23198/27327/80012/5931/143471/5706/5705/10197/192670/7316/10213/5709/5695/1911/4734/5714/1108/9861/10014/5715/5711/5928/5701/5688/84733/5687/57459/5685/5683/5698/5708/5692/54815/5686/5713/23512/57332/5728/5699/5710/5702/192669/3066/3065/7157/1107/23028/5719/23112/5704/6233/5716/57504/7311/1386/4343/8726/648/5694/23466/26523/7874/53615/5693/5721/5696/23608/5691/7314/6015 96 Rotavirus_C R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 54/1879 55/10654 4.906838949457045e-40 1.616674306505321e-38 8.468035084520053e-39 8454/5718/5689/8945/26271/5684/5720/5682/5700/122706/5707/991/5690/5717/9491/6500/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/51343/7311/5694/5693/5721/5696/5691/7314 54 Rotavirus_C R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 64/1879 72/10654 6.5666373747783856e-40 2.1080589726211638e-38 1.1041876071489701e-38 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/5717/9491/23198/898/143471/5706/5705/10197/8881/7316/10213/5709/5695/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/29882/5694/5693/5721/5696/5691/7314/996 64 Rotavirus_C R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 53/1879 54/10654 2.7968500039840065e-39 8.754140512469941e-38 4.585361980215884e-38 8454/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/6500/23198/143471/5706/5705/10197/7316/10213/5709/9978/5695/6790/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/23194/5694/5693/5721/5696/5691/7314 53 Rotavirus_C R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 66/1879 77/10654 6.186464082257846e-39 1.889134885606542e-37 9.895165913341818e-38 5718/5689/84617/5684/5720/5682/5700/122706/5707/5690/10382/5717/9491/23198/7277/143471/5706/10381/5705/10197/7278/7316/10213/5709/891/5695/983/5714/9861/5715/5711/5701/5688/5687/7846/113457/5685/5683/5698/347733/5708/3320/5692/5686/5713/5699/5710/5702/7157/81027/5719/5704/6233/3326/5716/7311/10383/5347/84790/5694/5693/5721/5696/7280/5691/7314 66 Rotavirus_C R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 69/1879 83/10654 7.065233567969625e-39 2.106112482642374e-37 1.1031680483320993e-37 8454/1147/5718/5689/8945/5684/5720/4790/6885/5966/5682/4772/5700/122706/5707/5690/5717/9491/6500/23198/143471/5706/5705/10197/8517/7316/10213/5709/5695/5970/4792/4793/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5478/5719/5704/6233/5716/7311/4794/808/3845/5694/3265/3551/801/5693/5721/5696/5691/7314/805 69 Rotavirus_C R-HSA-5610780 Degradation of GLI1 by the proteasome 56/1879 60/10654 7.397206773002032e-38 2.0580673066218988e-36 1.07800229697784e-36 8454/5718/5689/8945/5684/5720/2735/5682/5700/122706/5707/51684/5690/5717/9491/6500/23198/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5566/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/83737/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 56 Rotavirus_C R-HSA-5610783 Degradation of GLI2 by the proteasome 56/1879 60/10654 7.397206773002032e-38 2.0580673066218988e-36 1.07800229697784e-36 8454/5718/5689/8945/5684/5720/5682/5700/122706/5707/51684/5690/5717/9491/6500/23198/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5566/5715/2736/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 56 Rotavirus_C R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 56/1879 60/10654 7.397206773002032e-38 2.0580673066218988e-36 1.07800229697784e-36 8454/5718/5689/8945/5684/5720/5682/5700/122706/5707/51684/5690/5717/9491/6500/23198/143471/5706/5705/10197/2737/7316/10213/5709/9978/5695/5714/9861/5566/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 56 Rotavirus_C R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 51/1879 52/10654 9.06493443668747e-38 2.4183691898744936e-36 1.2667260848258025e-36 5718/5689/1019/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/595/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Rotavirus_C R-HSA-3371453 Regulation of HSF1-mediated heat shock response 61/1879 69/10654 9.078542485950574e-38 2.4183691898744936e-36 1.2667260848258025e-36 23165/3303/6118/6782/5903/573/55706/7175/9631/7531/116835/9530/3308/10049/348995/545/79023/472/57122/23636/3337/3313/10808/10762/23511/3305/53371/9261/9532/23279/4927/9688/79902/91582/6119/9883/2932/57805/259217/23225/3310/3309/7266/6767/9531/8086/22824/3306/27000/9972/23411/8021/9529/6396/129401/3304/3312/3297/55746/8480/51182 61 Rotavirus_C R-HSA-3371556 Cellular response to heat stress 71/1879 89/10654 1.1325292384950275e-37 2.9540137637411965e-36 1.5472932359263203e-36 23165/818/3303/6118/6782/5903/573/55706/7175/9631/7531/1915/116835/9530/3308/10049/348995/10013/545/79023/472/57122/23636/3337/3313/10808/10762/23511/3305/53371/9261/9532/23279/4927/9688/7415/79902/91582/6119/9883/2932/1387/57805/259217/23225/3310/3309/3320/2033/7266/6767/9531/8086/22824/3326/3306/27000/9972/23411/8021/9529/6396/129401/3304/3312/3297/55746/2288/8480/10728/51182 71 Rotavirus_C R-HSA-69242 S Phase 101/1879 161/10654 1.3312749718017462e-37 3.401543397338339e-36 1.781706353238427e-36 8454/5718/4172/6118/5689/1019/5684/994/5720/11065/902/8318/5682/246184/5700/122706/7321/5707/8697/5690/5717/5982/9491/6500/23198/898/10274/5925/4173/143471/5706/5705/10735/10197/4149/8881/5885/7316/10213/5709/9978/4174/993/5695/4331/5714/5111/5426/4171/4609/51433/9861/5715/4998/6119/5711/5928/2932/5701/5688/5687/6502/5685/5683/5698/5708/5692/5985/5686/5713/8243/9126/595/5699/4175/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/29882/5694/7465/5424/1022/5693/5721/5696/5691/4176/7314/996 101 Rotavirus_C R-HSA-72163 mRNA Splicing - Major Pathway 109/1879 183/10654 1.788647416583932e-37 4.424883143636402e-36 2.317725070191255e-36 7536/10921/22827/23451/53981/2963/6635/5434/5440/6633/220988/8683/6430/6632/6627/27339/11051/55696/23350/5430/4904/5436/9879/6428/9128/3184/8106/29894/3178/6637/23450/5441/3183/5438/5431/9092/5093/5435/10594/4686/9785/6625/5433/11338/1655/9343/3185/4116/3190/1477/6626/7307/6429/10181/2962/22938/988/10236/5437/10250/6629/4670/23020/10189/6434/9295/10465/6631/10949/55660/3181/5439/10421/1660/23283/2521/3191/10285/27316/6636/3187/1993/1665/23524/56949/6634/5094/51593/9775/3192/6427/3312/8175/5356/6426/57461/3188/84991/10291/5432/22916/5725/1479/26121/11100/10992/10262/6628/1994 109 Rotavirus_C R-HSA-4641258 Degradation of DVL 54/1879 57/10654 1.8024683732065216e-37 4.424883143636402e-36 2.317725070191255e-36 5718/5689/5684/5720/5682/5700/122706/5707/1856/5690/5717/9491/23198/143471/5706/5705/10197/8452/7316/10213/5709/9978/5695/5714/59349/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/1855/5716/1857/7311/5694/5693/5721/5696/5691/7314 54 Rotavirus_C R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 70/1879 88/10654 5.281205968874981e-37 1.2715518986598991e-35 6.660306312973913e-36 5393/5718/3303/5689/5684/5720/5682/5700/122706/5707/5690/3184/5717/9491/3315/23198/26986/143471/5706/5705/10197/7534/8125/7316/10213/5709/5695/9261/5714/9861/5715/5711/1432/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/55802/1981/5699/5710/5702/5719/5704/6233/5716/7514/7311/8021/5600/5694/56915/3304/3312/8570/5693/5721/5696/5691/118460/7529/22894/7314/1994 70 Rotavirus_C R-HSA-69239 Synthesis of DNA 83/1879 119/10654 3.133259639490288e-36 7.401586921965737e-35 3.8769031884855e-35 8454/5718/4172/6118/5689/5684/5720/11065/8318/5682/246184/5700/122706/7321/5707/8697/5690/5717/5982/9491/6500/23198/898/4173/143471/5706/5705/10197/8881/7316/10213/5709/9978/4174/5695/5714/5111/5426/4171/51433/9861/5715/4998/6119/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5985/5686/5713/5699/4175/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/29882/5694/5424/5693/5721/5696/5691/4176/7314/996 83 Rotavirus_C R-HSA-69275 G2/M Transition 112/1879 196/10654 4.2236231789810145e-36 9.792548555711538e-35 5.129273373304428e-35 8454/5718/5689/8945/84617/5684/994/5720/902/5682/22981/7531/5700/11190/122706/5707/203068/7532/84962/1454/5690/10382/5717/9491/6500/23198/121441/7277/143471/5706/10381/5705/10197/7278/1781/7316/10213/5709/9978/891/993/5695/4331/983/1639/6790/5714/10121/9861/9702/5566/5715/5519/5711/5928/5701/5688/5687/23291/7846/113457/5685/7283/5683/5698/347733/5708/3320/5692/5686/5713/80097/2033/10426/5699/5710/11064/5702/10540/5520/7157/81027/10733/85378/79866/5719/4751/5704/6233/3326/5716/7514/7311/23194/5518/10383/5347/84790/5694/1453/7465/27229/1022/5693/5721/5696/7280/5691/5500/7314/5515/1778 112 Rotavirus_C R-HSA-5607764 CLEC7A (Dectin-1) signaling 75/1879 101/10654 6.858880462945013e-36 1.561330607201301e-34 8.178148379741136e-35 8454/1147/5718/5689/8945/5684/5720/4790/6885/5682/4772/5700/122706/7321/5707/5690/9039/5717/9491/6500/23198/143471/5706/5705/841/10197/8517/7316/10213/5709/5695/9020/7335/5970/4792/5714/9861/7322/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/10454/5702/9040/5719/5704/6233/5716/7311/5971/808/7334/5694/3551/801/5693/5721/5696/997/5691/4791/7314/805 75 Rotavirus_C R-HSA-180534 Vpu mediated degradation of CD4 50/1879 52/10654 1.1135310722291265e-35 2.323568170718111e-34 1.2170699263135891e-34 5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/6500/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Rotavirus_C R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/1879 52/10654 1.1135310722291265e-35 2.323568170718111e-34 1.2170699263135891e-34 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/472/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Rotavirus_C R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 50/1879 52/10654 1.1135310722291265e-35 2.323568170718111e-34 1.2170699263135891e-34 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Rotavirus_C R-HSA-69610 p53-Independent DNA Damage Response 50/1879 52/10654 1.1135310722291265e-35 2.323568170718111e-34 1.2170699263135891e-34 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Rotavirus_C R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 50/1879 52/10654 1.1135310722291265e-35 2.323568170718111e-34 1.2170699263135891e-34 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Rotavirus_C R-HSA-195253 Degradation of beta-catenin by the destruction complex 66/1879 82/10654 1.5334809420407397e-35 3.1474067859590265e-34 1.6485912457142032e-34 8454/5718/5689/51176/8945/5684/5720/5682/1499/5700/139285/122706/5707/5690/5717/9491/6500/23198/143471/5706/5705/10197/7316/10213/5709/9978/5695/83439/5714/6934/9861/5715/5519/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/324/5699/8312/5529/5710/5702/3065/5719/5704/6233/6932/5716/7311/5518/5694/5693/5721/5696/5691/7314/5515 66 Rotavirus_C R-HSA-453274 Mitotic G2-G2/M phases 112/1879 198/10654 1.563087713789648e-35 3.1564287381687734e-34 1.653316885723176e-34 8454/5718/5689/8945/84617/5684/994/5720/902/5682/22981/7531/5700/11190/122706/5707/203068/7532/84962/1454/5690/10382/5717/9491/6500/23198/121441/7277/143471/5706/10381/5705/10197/7278/1781/7316/10213/5709/9978/891/993/5695/4331/983/1639/6790/5714/10121/9861/9702/5566/5715/5519/5711/5928/5701/5688/5687/23291/7846/113457/5685/7283/5683/5698/347733/5708/3320/5692/5686/5713/80097/2033/10426/5699/5710/11064/5702/10540/5520/7157/81027/10733/85378/79866/5719/4751/5704/6233/3326/5716/7514/7311/23194/5518/10383/5347/84790/5694/1453/7465/27229/1022/5693/5721/5696/7280/5691/5500/7314/5515/1778 112 Rotavirus_C R-HSA-156842 Eukaryotic Translation Elongation 71/1879 93/10654 2.1594391385033644e-35 4.291456827628909e-34 2.2478372318923913e-34 6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/1917/1938/6147/6129/1915/6217/6222/6176/6152/6136/6125/1937/6224/6146/6141/6202/6232/6134/6169/6160/6155/6175/6218/1933/6209/6193/6210/6229/11224/6205/6165/6130/6204/6228/23521/6156/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/6133/6230 71 Rotavirus_C R-HSA-180585 Vif-mediated degradation of APOBEC3G 51/1879 54/10654 2.9853006972551765e-35 5.839994489005439e-34 3.0589512078782483e-34 60489/5718/5689/5684/8065/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Rotavirus_C R-HSA-72172 mRNA Splicing 109/1879 191/10654 4.392785395919022e-35 8.461180485677869e-34 4.431911419688341e-34 7536/10921/22827/23451/53981/2963/6635/5434/5440/6633/220988/8683/6430/6632/6627/27339/11051/55696/23350/5430/4904/5436/9879/6428/9128/3184/8106/29894/3178/6637/23450/5441/3183/5438/5431/9092/5093/5435/10594/4686/9785/6625/5433/11338/1655/9343/3185/4116/3190/1477/6626/7307/6429/10181/2962/22938/988/10236/5437/10250/6629/4670/23020/10189/6434/9295/10465/6631/10949/55660/3181/5439/10421/1660/23283/2521/3191/10285/27316/6636/3187/1993/1665/23524/56949/6634/5094/51593/9775/3192/6427/3312/8175/5356/6426/57461/3188/84991/10291/5432/22916/5725/1479/26121/11100/10992/10262/6628/1994 109 Rotavirus_C R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 71/1879 95/10654 2.4143970109841144e-34 4.580037966291077e-33 2.3989941592393994e-33 6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/6141/26986/6202/6232/6134/6169/6160/4686/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6130/6204/6228/23521/1981/6156/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/9045/5976/6187/6168/22916/6208/6137/6122/6133/6230 71 Rotavirus_C R-HSA-2871837 FCERI mediated NF-kB activation 65/1879 82/10654 2.886519301826127e-34 5.3939136804273304e-33 2.8252969757072694e-33 8454/1147/5718/5689/8945/5684/5720/4790/6885/5682/5700/122706/7321/5707/5690/5717/9491/6500/23198/143471/5706/5705/10197/8517/7316/10213/5709/5695/7335/5970/4792/5714/9861/7322/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/10454/5702/5719/5704/6233/5716/7311/7334/5694/3551/5693/5721/5696/997/5691/7314 65 Rotavirus_C R-HSA-4641257 Degradation of AXIN 51/1879 55/10654 3.410681687438391e-34 6.265534087256379e-33 3.2818460874060236e-33 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/64750/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/8312/5710/5702/8313/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Rotavirus_C R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 48/1879 50/10654 3.4530499362674936e-34 6.265534087256379e-33 3.2818460874060236e-33 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 48 Rotavirus_C R-HSA-73762 RNA Polymerase I Transcription Initiation 46/1879 47/10654 5.342702682570371e-34 9.555805369397293e-33 5.005268828934348e-33 5434/5440/902/9015/2648/79101/2074/9112/9219/9014/30834/25885/404672/5931/221830/5441/51082/5435/7270/4331/9013/7343/1108/2966/8850/5928/5437/57459/2965/54815/64425/2068/3066/3065/2071/1107/10849/2968/57504/84172/2967/6908/53615/1022/10919/9533 46 Rotavirus_C R-HSA-156902 Peptide chain elongation 68/1879 89/10654 5.576073244141305e-34 9.696171807867935e-33 5.078791858333381e-33 6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/1938/6147/6129/1915/6217/6222/6176/6152/6136/6125/6224/6146/6141/6202/6232/6134/6169/6160/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6130/6204/6228/23521/6156/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/6133/6230 68 Rotavirus_C R-HSA-192823 Viral mRNA Translation 68/1879 89/10654 5.576073244141305e-34 9.696171807867935e-33 5.078791858333381e-33 6138/6144/6203/6227/9349/4736/2926/6206/6194/6234/6191/6128/51121/6132/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/6141/6202/6232/6134/6169/6160/6155/6175/6218/5611/6209/6193/6210/6229/11224/6205/6165/6130/6204/6228/23521/6156/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/6133/6230 68 Rotavirus_C R-HSA-927802 Nonsense-Mediated Decay (NMD) 79/1879 115/10654 8.587738351511632e-34 1.4529524886611573e-32 7.610470829291246e-33 10921/9887/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/6141/26986/6202/6232/6134/6169/6160/4686/6155/6175/6218/4116/6209/6193/6210/6229/11224/6205/6165/6130/6204/6228/23521/55802/1981/6156/6143/6181/6124/5520/6207/6139/6233/7311/6223/25873/5518/3921/6188/6189/9775/6135/6201/9045/5976/6187/6168/22916/6208/6137/6122/6133/5515/6230 79 Rotavirus_C R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 79/1879 115/10654 8.587738351511632e-34 1.4529524886611573e-32 7.610470829291246e-33 10921/9887/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/6141/26986/6202/6232/6134/6169/6160/4686/6155/6175/6218/4116/6209/6193/6210/6229/11224/6205/6165/6130/6204/6228/23521/55802/1981/6156/6143/6181/6124/5520/6207/6139/6233/7311/6223/25873/5518/3921/6188/6189/9775/6135/6201/9045/5976/6187/6168/22916/6208/6137/6122/6133/5515/6230 79 Rotavirus_C R-HSA-112382 Formation of RNA Pol II elongation complex 54/1879 61/10654 1.2812466825574284e-33 2.110685324423553e-32 1.1055632731762853e-32 85403/2963/6917/5434/5440/902/6830/5430/5436/9646/404672/79577/6749/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/4298/54623/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/23168/55677/2967/27125/11198/904/7936/6829/51497/4300/1022/5432/22916/8178/55840/80349/123169/25920 54 Rotavirus_C R-HSA-75955 RNA Polymerase II Transcription Elongation 54/1879 61/10654 1.2812466825574284e-33 2.110685324423553e-32 1.1055632731762853e-32 85403/2963/6917/5434/5440/902/6830/5430/5436/9646/404672/79577/6749/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/4298/54623/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/23168/55677/2967/27125/11198/904/7936/6829/51497/4300/1022/5432/22916/8178/55840/80349/123169/25920 54 Rotavirus_C R-HSA-5610787 Hedgehog 'off' state 78/1879 113/10654 1.3129202800140552e-33 2.1347742734773986e-32 1.1181809083373291e-32 8454/5718/5689/8945/84617/5684/5720/2735/5682/5575/5700/122706/5707/51684/5690/27152/10382/5717/9491/6500/23198/57539/7277/143471/5706/10381/5705/10197/7278/5573/2737/7316/10213/5709/9978/5695/5727/5714/9861/5566/5715/2736/5711/2932/5701/5688/5687/7846/113457/5685/5683/5698/347733/5708/5692/5686/5713/5699/5710/5702/81027/83737/5719/9742/5704/6233/5716/7311/10383/23432/84790/5694/5693/5721/5696/7280/5691/7314 78 Rotavirus_C R-HSA-9604323 Negative regulation of NOTCH4 signaling 50/1879 54/10654 1.8335056667733203e-33 2.943011660000253e-32 1.541530405397812e-32 8454/5718/5689/5684/5720/5682/5700/5707/5690/5717/9491/6500/5706/5705/10197/7534/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/55294/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Rotavirus_C R-HSA-8939902 Regulation of RUNX2 expression and activity 60/1879 73/10654 2.1619244483068437e-33 3.4262397585824915e-32 1.7946421469622434e-32 8454/57154/5718/5689/5684/5720/5682/5700/122706/5707/10273/5690/5717/9491/6500/23198/143471/5706/5705/10197/7316/10213/5709/9978/865/5695/11059/5714/2099/9861/5715/5711/2932/5701/5688/5687/6502/2908/5685/5683/5698/5708/5692/5686/5713/55294/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 60 Rotavirus_C R-HSA-68949 Orc1 removal from chromatin 59/1879 71/10654 2.2465199061237333e-33 3.5158036530836427e-32 1.8415551335724814e-32 8454/5718/4172/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/6500/23198/4173/143471/5706/5705/10197/7316/10213/5709/9978/4174/5695/5714/4171/9861/5715/4998/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/5699/4175/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/4176/7314 59 Rotavirus_C R-HSA-5688426 Deubiquitination 141/1879 297/10654 3.02470243152911e-33 4.6752190670054884e-32 2.4488494020047244e-32 9960/5718/5689/10600/23032/5684/8295/5720/114785/3607/23326/221937/7186/6885/6314/5682/2648/93624/5700/10474/122706/7321/5707/991/83444/8237/171023/4738/5690/55611/2625/9817/51720/5717/9491/23198/63967/409/6478/1080/3091/9101/143471/5706/5705/57695/4287/55031/27005/10197/7706/8517/86/64750/580/7416/29086/8239/7316/10213/5709/993/5695/79155/4792/983/8314/55252/5714/2099/9100/1643/4609/7415/9861/5715/64426/8850/7128/5711/5701/5688/79913/5687/6502/9099/5685/114803/5683/5698/5708/5692/54617/5686/5713/324/2033/408/55777/221656/5728/5699/8312/5710/10454/8473/5702/219333/7157/9958/8313/63891/5719/57599/5704/6233/5716/672/7311/367/6881/79184/51616/387/60/23770/8607/3054/1540/29761/5694/7874/54764/5693/154/5721/5696/5691/7314/4193/7528 141 Rotavirus_C R-HSA-69306 DNA Replication 83/1879 127/10654 5.42576883685597e-33 8.284222663102041e-32 4.339222060797522e-32 8454/5718/4172/6118/5689/5684/5720/11065/8318/5682/246184/5700/122706/7321/5707/8697/5690/5717/5982/9491/6500/23198/898/4173/143471/5706/5705/10197/8881/7316/10213/5709/9978/4174/5695/5714/5111/5426/4171/51433/9861/5715/4998/6119/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5985/5686/5713/5699/4175/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/29882/5694/5424/5693/5721/5696/5691/4176/7314/996 83 Rotavirus_C R-HSA-5687128 MAPK6/MAPK4 signaling 67/1879 89/10654 8.362075255586791e-33 1.2613636409632122e-31 6.606940880444605e-32 5718/5689/27161/3725/5684/5720/5682/5700/10642/122706/5707/5690/57690/5717/9491/3315/23198/27327/143471/5706/5705/10197/3337/192670/7316/10213/5709/5695/983/5714/4609/9861/5566/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/192669/998/5719/23112/5704/6233/5716/7514/7311/5896/4343/5694/26523/8202/5693/5721/5696/5691/7314 67 Rotavirus_C R-HSA-169911 Regulation of Apoptosis 49/1879 53/10654 9.837875975978389e-33 1.4663119907053505e-31 7.680447033877866e-32 5718/5689/5684/5720/5682/4976/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 49 Rotavirus_C R-HSA-8878159 Transcriptional regulation by RUNX3 70/1879 96/10654 1.0223846821183823e-32 1.5059124964849584e-31 7.887871912814268e-32 57154/5718/5689/51176/5684/5720/5682/1499/2648/10018/5700/5707/5690/5717/9491/5706/5705/10197/64750/7316/10213/5709/865/5695/9759/83439/10413/5714/6934/4609/9861/5715/22938/8850/5711/5701/5688/1387/5687/5685/5683/5698/5708/5692/5686/5713/2033/595/5699/5710/5702/7157/861/5719/5704/6233/6932/5716/7311/25937/3845/5694/4851/5693/5721/5696/5691/3676/7314/4193 70 Rotavirus_C R-HSA-5658442 Regulation of RAS by GAPs 57/1879 68/10654 1.0947768894331142e-32 1.5937914715933243e-31 8.348176280499756e-32 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/8452/7316/10213/5709/9978/5695/84078/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/399473/3845/5694/3265/200734/4763/5693/5721/5696/5691/7314/161742 57 Rotavirus_C R-HSA-5632684 Hedgehog 'on' state 65/1879 85/10654 1.4359462911270288e-32 2.066442248840276e-31 1.0823890373528602e-31 57154/5718/5689/5684/5720/2735/339745/5682/5700/122706/5707/22873/51684/5690/5717/9491/23198/409/79577/143471/5706/5705/10197/64750/8452/2737/7316/10213/5709/9978/5695/5727/5714/9861/5715/2736/8405/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/408/5699/5710/5702/83737/5719/5704/6233/5716/7311/23432/5694/5693/5721/5696/5691/7314 65 Rotavirus_C R-HSA-8941858 Regulation of RUNX3 expression and activity 50/1879 55/10654 1.6757880647068279e-32 2.3841893829692596e-31 1.248822923818605e-31 57154/5718/5689/5684/5720/5682/5700/5707/5690/5717/9491/5706/5705/10197/64750/7316/10213/5709/865/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/2033/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314/4193 50 Rotavirus_C R-HSA-69541 Stabilization of p53 51/1879 57/10654 2.5054150416302624e-32 3.5244714967652678e-31 1.846095293832825e-31 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/472/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314/4193 51 Rotavirus_C R-HSA-5358351 Signaling by Hedgehog 89/1879 149/10654 6.6926093939352e-31 9.310163290229856e-30 4.876603102247519e-30 8454/57154/5718/5689/8945/84617/5684/5720/2735/339745/5682/5575/5700/122706/5707/22873/51684/5690/27152/10382/5717/9491/6500/23198/409/79577/57539/7277/143471/5706/10381/5705/10197/7278/64750/5573/8452/2737/7316/10213/5709/9978/5695/5727/5714/7415/9861/5566/5715/2736/8405/5711/2932/5701/5688/5687/7846/113457/5685/5683/5698/347733/5708/5692/5686/5713/408/5699/5710/5702/81027/83737/5719/9742/5704/6233/5716/7311/10383/23432/84790/5694/5693/5721/5696/7280/5691/5034/7314 89 Rotavirus_C R-HSA-9013694 Signaling by NOTCH4 62/1879 82/10654 1.2566658364481066e-30 1.728951238717615e-29 9.056134367925626e-30 8454/5718/5689/5684/5720/5682/2648/5700/5707/5690/5717/9491/6500/23385/5706/5705/10197/7534/7316/10213/5709/9978/5695/5714/9861/5715/22938/8850/5711/5701/5688/1387/5687/5685/5683/5698/5708/59/5692/5686/5713/2033/55294/5699/5710/5702/5719/5704/83464/6233/5716/7311/55851/51107/5694/4851/5693/5663/5721/5696/5691/7314 62 Rotavirus_C R-HSA-72766 Translation 135/1879 291/10654 1.4700220016495521e-30 2.000508202244825e-29 1.0478532117021407e-29 6138/6144/6203/6182/6227/9349/57505/4736/51253/6206/6194/6234/6191/6128/51121/6132/1917/65993/1938/6147/56945/8666/6129/54534/1915/6217/26284/80222/6222/6176/6152/6136/60488/79590/8668/6125/1937/6727/23395/7818/6224/6146/6141/6184/26986/6202/64949/65003/6150/28998/6232/58477/10573/6134/6169/6160/6731/6155/6748/6175/219927/6218/64963/1933/64960/10240/6209/6193/6210/6229/11224/6205/6165/6130/6204/64969/51081/8663/6228/23521/54148/54938/51069/23107/65008/1981/78988/6156/6143/1973/6181/6124/6185/28973/740/6207/6139/6745/90480/6233/1975/55168/2193/51067/28957/9801/7311/6223/25873/64928/8664/6730/3921/6188/6189/10667/6135/6201/9045/51649/6187/54998/64965/6168/6208/51073/6137/92259/7284/6122/6133/54460/65080/55037/6230 135 Rotavirus_C R-HSA-72689 Formation of a pool of free 40S subunits 70/1879 101/10654 1.8916464673211495e-30 2.546603631275354e-29 1.3338944529044437e-29 6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/6147/8666/6129/6217/6222/6176/6152/6136/8668/6125/6224/6146/6141/6202/6232/6134/6169/6160/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6130/6204/8663/6228/23521/6156/6143/6181/6124/6207/6139/6233/7311/6223/25873/8664/3921/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/6133/6230 70 Rotavirus_C R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 74/1879 111/10654 2.164468973283541e-30 2.882888462288291e-29 1.5100382646759755e-29 6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/6147/8666/6129/6217/6222/6176/6152/6136/8668/6125/6224/6146/6141/26986/6202/6232/6134/6169/6160/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6130/6204/8663/6228/23521/1981/6156/6143/1973/6181/6124/6207/6139/6233/1975/7311/6223/25873/8664/3921/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/6133/6230 74 Rotavirus_C R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 49/1879 56/10654 4.469372543445421e-30 5.890162551993334e-29 3.0852289136470886e-29 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 49 Rotavirus_C R-HSA-68867 Assembly of the pre-replicative complex 55/1879 68/10654 5.221821989484499e-30 6.8101261779527e-29 3.567099889746538e-29 5718/4172/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/4173/143471/5706/5705/10197/7316/10213/5709/4174/5695/5714/4171/9861/5715/4998/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/4175/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/4176/7314 55 Rotavirus_C R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 74/1879 112/10654 5.3035127665645514e-30 6.845358746122493e-29 3.585554480270988e-29 6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/6147/6129/6217/6222/6176/6152/6136/6125/6727/6224/6146/6141/6184/6202/6232/58477/6134/6169/6160/6731/6155/6748/6175/6218/6209/6193/6210/6229/11224/6205/6165/6130/6204/6228/23521/6156/6143/6181/6124/6185/6207/6139/6745/6233/7311/6223/25873/6730/3921/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/6133/6230 74 Rotavirus_C R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 51/1879 60/10654 5.854861375999381e-30 7.479884125256352e-29 3.917914755368007e-29 8454/5718/5689/1019/5684/5720/5682/5700/5707/5690/5717/9491/6500/898/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/595/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Rotavirus_C R-HSA-2408557 Selenocysteine synthesis 66/1879 93/10654 9.377837263310196e-30 1.1741052253664365e-28 6.149886963202371e-29 6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/6141/6202/6232/6134/6169/6160/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6130/6204/6228/23521/6156/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/6133/6230 66 Rotavirus_C R-HSA-72764 Eukaryotic Translation Termination 66/1879 93/10654 9.377837263310196e-30 1.1741052253664365e-28 6.149886963202371e-29 6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/6147/6129/6217/6222/6176/6152/6136/6125/6224/6146/6141/6202/6232/6134/6169/6160/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6130/6204/6228/23521/6156/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/6133/6230 66 Rotavirus_C R-HSA-9020702 Interleukin-1 signaling 70/1879 103/10654 1.3003348462975766e-29 1.6119002253114514e-28 8.443028757096303e-29 8454/1147/5718/5689/8945/1326/5684/351/5720/4790/6885/5682/5700/122706/5707/5690/8878/5717/9491/6500/23198/143471/5706/5705/10197/8517/7316/10213/5709/9978/5695/79155/7335/5970/4792/4793/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/10454/5702/5719/3654/5704/6233/5716/7311/7334/5694/3551/5693/5721/5696/5691/4791/7314 70 Rotavirus_C R-HSA-5678895 Defective CFTR causes cystic fibrosis 51/1879 61/10654 2.967492685055397e-29 3.6424518055778012e-28 1.907892613817866e-28 5718/5689/5684/5720/5682/5700/122706/5707/79139/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Rotavirus_C R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 62/1879 85/10654 4.0225188553636947e-29 4.889508356228491e-28 2.5610927408191943e-28 8454/5718/5689/1019/5684/994/5720/902/5682/5700/5707/5690/5717/9491/6500/898/5925/5706/5705/10197/4149/7316/10213/5709/993/5695/4331/5714/4609/9861/5715/5711/5928/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/595/5699/5710/5702/5719/5704/6233/5716/51343/7311/5694/7465/1022/5693/5721/5696/5691/7314 62 Rotavirus_C R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 73/1879 112/10654 4.89144459757032e-29 5.888546765536577e-28 3.084382575188572e-28 6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/6147/8666/6129/6217/6222/6176/6152/6136/8668/6125/6224/6146/6141/6202/6232/6134/6169/6160/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6130/6204/8663/6228/23521/1981/6156/6143/1973/6181/6124/6207/6139/6233/1975/7311/6223/25873/8664/3921/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/6133/6230 73 Rotavirus_C R-HSA-162599 Late Phase of HIV Life Cycle 83/1879 139/10654 7.084434936492483e-29 8.4473452766558e-28 4.424664627002323e-28 23165/2963/6917/5434/5440/5903/902/55706/7175/9631/5430/5436/404672/6749/348995/10015/79023/57122/5441/23636/5438/10762/5431/7469/23511/5435/4686/7316/5433/53371/4331/23279/4927/9688/8148/2966/8731/79902/9150/9525/2962/23327/9883/5437/8812/23225/2965/905/2068/5439/2071/5901/8086/5478/6827/6233/2968/7514/1025/7311/9972/6881/2967/51616/6908/8021/11198/6396/129401/904/7936/6829/1104/51497/1022/5432/55746/22916/8178/8480/6877/7314/25920 83 Rotavirus_C R-HSA-69615 G1/S DNA Damage Checkpoints 54/1879 68/10654 9.897623808245812e-29 1.1690400950871468e-27 6.123356139560219e-28 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/898/143471/5706/472/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/7157/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314/4193 54 Rotavirus_C R-HSA-69481 G2/M Checkpoints 93/1879 168/10654 1.1224371566244232e-28 1.3133563739194186e-27 6.879275440993759e-28 5718/4172/6118/5689/5684/5720/8318/5682/7531/5700/122706/5707/10111/7532/10971/5690/51720/5717/5982/9491/23198/63967/7533/4173/143471/545/5706/472/5705/10197/7336/7534/580/29086/7316/10213/5709/4174/891/993/5695/983/641/5714/4171/9861/5715/9656/4998/6119/5711/5701/10524/5688/4683/5687/5685/5683/5698/5708/5692/5985/5686/5713/165918/5699/4175/5710/1111/5702/7157/5719/8924/5704/6233/5716/672/5932/7158/7311/9025/79184/7334/5694/7465/5693/5721/5696/83695/5691/4176/7529/7314 93 Rotavirus_C R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 47/1879 54/10654 1.1445745013869322e-28 1.3268585886448512e-27 6.949999165341703e-28 9318/6917/5434/5440/902/2074/27339/5430/5436/404672/5441/5438/5431/8450/5435/7316/9978/5433/4331/64708/2966/10980/5437/1161/1642/2965/10920/2033/2068/5439/10987/2071/6233/2873/2968/7311/2967/56949/8533/7874/57461/1022/5432/50813/7314/51138/8451 47 Rotavirus_C R-HSA-202424 Downstream TCR signaling 67/1879 98/10654 1.2357129982522193e-28 1.4193694255153931e-27 7.434564924298722e-28 5295/8454/1147/5718/5689/8945/5684/5720/4790/6885/5682/5700/122706/7321/5707/5690/5717/9491/6500/23198/143471/5706/5705/10197/8517/7316/10213/5709/5695/7335/5970/4792/5714/9861/7322/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5728/5699/5710/5702/5719/5704/6233/5716/7311/5296/7334/5694/3551/5693/5721/5696/997/5691/7314 67 Rotavirus_C R-HSA-8878171 Transcriptional regulation by RUNX1 116/1879 239/10654 1.4401563482786502e-28 1.6391597709498816e-27 8.585812487823915e-28 55904/1912/5718/9070/84661/5689/27161/894/5684/5720/902/11091/6597/5682/5700/122706/5707/8535/8085/3674/6045/9021/5690/2625/57690/5717/5929/9491/23198/27327/80012/143471/5706/6598/5705/10197/6599/192670/200845/86/7316/10213/5709/865/5695/4331/1911/6603/10413/2623/5714/23309/2099/122809/9861/5715/8850/5711/5701/5688/1387/84733/5687/5685/5683/8289/5698/5708/5692/5686/5713/10138/2033/6605/57332/595/5699/8312/5710/5702/192669/3065/83737/861/5719/23112/23067/5704/6233/9757/5716/2811/7311/6688/58508/161882/25942/9739/4343/648/3276/5694/6601/23466/26523/7057/1022/5693/5721/4297/5696/5691/55193/7314/6015/55170 116 Rotavirus_C R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 98/1879 185/10654 4.113835885672078e-28 4.6401103863616586e-27 2.430459702962261e-27 5393/6138/6144/2091/6203/6227/23246/9349/4736/6206/6194/57418/6234/22803/6191/6128/51121/6132/6147/6129/6217/6222/1454/81887/6176/6152/6136/10528/84135/27043/6125/6224/6146/6141/6202/6232/134430/6134/6169/6160/6155/6175/6218/5394/6209/6193/6210/6229/11224/6205/6165/6130/6204/6228/23521/23481/55131/6156/117246/5822/6143/6181/6124/6207/10969/6139/55759/10556/6233/25926/7311/6223/25873/83732/26168/3921/6188/6189/11103/26354/6135/6201/56915/1453/9045/6187/4691/6168/6208/6137/22984/10813/118460/6122/6133/22894/9188/6230 98 Rotavirus_C R-HSA-5689603 UCH proteinases 68/1879 102/10654 5.079916664586463e-28 5.67862112862701e-27 2.974424889132863e-27 5718/5689/5684/5720/114785/3607/221937/5682/5700/122706/5707/83444/171023/4738/5690/5717/9491/23198/143471/5706/5705/10197/86/580/7316/10213/5709/5695/8314/55252/5714/9861/5715/5711/5701/5688/79913/5687/5685/5683/5698/5708/5692/54617/5686/5713/55777/221656/5699/5710/8473/5702/9958/5719/5704/6233/5716/7311/60/8607/3054/5694/5693/5721/5696/5691/7314/7528 68 Rotavirus_C R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 52/1879 65/10654 5.344911960739721e-28 5.9219732520762226e-27 3.1018911518778258e-27 3725/2963/6917/5434/5440/902/5430/5436/404672/6749/545/472/5441/5438/5431/7469/5435/5433/4331/1643/2966/9150/2962/9656/5437/8812/2177/2965/51755/905/2068/5439/1111/2071/7157/55215/6827/2968/672/1025/2353/2967/1386/11198/904/7936/6829/51497/1022/5432/8178/25920 52 Rotavirus_C R-HSA-69206 G1/S Transition 79/1879 131/10654 5.988543707127417e-28 6.57689186081011e-27 3.444933268273666e-27 8454/5718/4172/6118/5689/26271/1019/5684/5720/902/8318/5682/5700/5707/5690/5717/9491/6500/898/5925/4173/5706/5705/10197/4149/7316/10213/5709/4174/891/993/5695/4331/983/5714/5111/5426/4171/4609/9861/5715/5519/4998/6119/5711/5928/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/595/5699/4175/5710/5702/3065/5719/5704/6233/5716/7311/5518/5694/7465/1022/5693/5721/5696/5691/4176/7314/5515 79 Rotavirus_C R-HSA-8868773 rRNA processing in the nucleus and cytosol 101/1879 195/10654 6.764059431307e-28 7.364002093909881e-27 3.857216499500468e-27 5393/6138/6144/2091/6203/6227/23246/9349/4736/6206/6194/57418/6234/22803/6191/6128/51121/6132/6147/6129/6217/55226/6222/1454/81887/6176/6152/6136/10528/84135/27043/6125/4839/6224/6146/6141/6202/6232/134430/6134/6169/6160/6155/6175/6218/5394/6209/6193/6210/6229/11224/6205/6165/6130/6204/1736/6228/23521/23481/55131/6156/117246/5822/6143/6181/6124/6207/10969/6139/55759/10556/6233/25926/7311/6223/25873/83732/26168/3921/6188/6189/11103/26354/6135/6201/56915/1453/9045/6187/4691/6168/6208/6137/22984/10813/118460/6122/6133/22894/9188/6230 101 Rotavirus_C R-HSA-5387390 Hh mutants abrogate ligand secretion 49/1879 59/10654 6.945183463643196e-28 7.431939911522462e-27 3.8928018874041476e-27 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 49 Rotavirus_C R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 49/1879 59/10654 6.945183463643196e-28 7.431939911522462e-27 3.8928018874041476e-27 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/4998/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 49 Rotavirus_C R-HSA-69202 Cyclin E associated events during G1/S transition 60/1879 83/10654 7.219074573815699e-28 7.659560480014623e-27 4.012028063770901e-27 8454/5718/5689/1019/5684/5720/902/5682/5700/5707/5690/5717/9491/6500/898/5925/5706/5705/10197/4149/7316/10213/5709/993/5695/4331/5714/4609/9861/5715/5711/5928/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/595/5699/5710/5702/5719/5704/6233/5716/7311/5694/7465/1022/5693/5721/5696/5691/7314 60 Rotavirus_C R-HSA-8878166 Transcriptional regulation by RUNX2 75/1879 121/10654 1.0746713868235907e-27 1.1306626691622988e-26 5.922337673517002e-27 8454/57154/5718/5689/1019/5684/8841/5720/5682/5700/122706/5707/10273/5690/5717/9491/6500/23198/5925/10013/143471/5706/5705/10197/2737/7316/10213/5709/9978/891/865/5695/11059/9759/983/10413/5714/2099/9861/5715/2736/5711/2932/5701/5688/5687/6502/2908/5685/5683/5698/5708/5692/5686/5713/595/55294/5699/5710/5702/861/5719/5704/6233/5716/7311/25937/367/10432/5694/5693/5721/5696/5691/7314 75 Rotavirus_C R-HSA-162587 HIV Life Cycle 86/1879 152/10654 1.6094747943370207e-27 1.6792187020916248e-26 8.795638569052314e-27 23165/2963/6917/5434/5440/5903/902/55706/7175/9631/5430/5436/7520/404672/6749/348995/10015/79023/57122/5441/23636/5438/10762/5431/7469/23511/5435/4686/7316/5433/53371/4331/23279/4927/9688/8148/2966/8731/79902/9150/9525/2962/23327/9883/5437/8812/23225/8815/2965/905/2068/5439/2071/5901/8086/5478/3836/6827/6233/2968/7514/1025/7311/9972/6881/2967/51616/6908/8021/11198/6396/129401/904/7936/6829/1104/51497/1022/5432/55746/22916/8178/8480/6877/7314/25920 86 Rotavirus_C R-HSA-72613 Eukaryotic Translation Initiation 74/1879 119/10654 1.796190280125339e-27 1.8433034678007577e-26 9.655103921640088e-27 6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/6147/8666/6129/6217/6222/6176/6152/6136/8668/6125/6224/6146/6141/26986/6202/6232/6134/6169/6160/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6130/6204/8663/6228/23521/1981/6156/6143/1973/6181/6124/6207/6139/6233/1975/7311/6223/25873/8664/3921/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/6133/6230 74 Rotavirus_C R-HSA-72737 Cap-dependent Translation Initiation 74/1879 119/10654 1.796190280125339e-27 1.8433034678007577e-26 9.655103921640088e-27 6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/6147/8666/6129/6217/6222/6176/6152/6136/8668/6125/6224/6146/6141/26986/6202/6232/6134/6169/6160/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6130/6204/8663/6228/23521/1981/6156/6143/1973/6181/6124/6207/6139/6233/1975/7311/6223/25873/8664/3921/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/6133/6230 74 Rotavirus_C R-HSA-69563 p53-Dependent G1 DNA Damage Response 52/1879 66/10654 2.093629282720571e-27 2.1138902112630283e-26 1.107241972100947e-26 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/898/143471/5706/472/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314/4193 52 Rotavirus_C R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 52/1879 66/10654 2.093629282720571e-27 2.1138902112630283e-26 1.107241972100947e-26 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/898/143471/5706/472/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314/4193 52 Rotavirus_C R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 44/1879 50/10654 2.392796687805208e-27 2.3966251625056962e-26 1.2553367044232795e-26 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/5694/5693/5721/5696/5691 44 Rotavirus_C R-HSA-4608870 Asymmetric localization of PCP proteins 51/1879 64/10654 2.4797528085382795e-27 2.464008346261846e-26 1.2906315787129057e-26 57154/5718/5689/5684/5720/5682/5700/122706/5707/1856/5690/5717/9491/23198/143471/5706/5705/10197/64750/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Rotavirus_C R-HSA-983705 Signaling by the B Cell Receptor (BCR) 71/1879 112/10654 3.6982635924231626e-27 3.645847258042362e-26 1.9096711297800498e-26 5295/8454/1147/5718/5689/8945/5684/5720/4790/6885/5966/5682/4772/5700/122706/5707/5690/5717/9491/6500/23198/143471/5706/5705/10197/8517/7316/10213/5709/5695/5970/4792/4793/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5478/5719/5704/6233/2885/5716/7311/4794/808/3845/5694/3265/3551/801/5693/5721/5696/5691/7314/805 71 Rotavirus_C R-HSA-72312 rRNA processing 103/1879 205/10654 5.0480802899078e-27 4.937653533566067e-26 2.5863108722142754e-26 5393/6138/6144/2091/6203/6227/23246/9349/4736/6206/6194/57418/6234/22803/6191/6128/51121/6132/6147/6129/6217/3028/55226/6222/1454/81887/6176/6152/6136/10528/84135/27043/6125/4839/6224/6146/6141/6202/6232/134430/6134/6169/6160/6155/6175/6218/54931/5394/6209/6193/6210/6229/11224/6205/6165/6130/6204/1736/6228/23521/23481/55131/6156/117246/5822/6143/6181/6124/6207/10969/6139/55759/10556/6233/25926/7311/6223/25873/83732/26168/3921/6188/6189/11103/26354/6135/6201/56915/1453/9045/6187/4691/6168/6208/6137/22984/10813/118460/6122/6133/22894/9188/6230 103 Rotavirus_C R-HSA-212165 Epigenetic regulation of gene expression 84/1879 149/10654 9.334768017397397e-27 9.059790354869411e-26 4.7454593837932095e-26 8467/23451/5252/5434/5440/902/9015/10514/51742/79595/2648/79101/2074/2146/29128/1788/9112/9219/1786/6839/9014/29115/30834/25885/404672/5931/221830/5441/51082/26147/11335/8932/5435/8819/9031/7270/4331/9013/23309/7343/1108/2966/64426/79685/8850/5928/2932/29947/5437/7913/57459/1789/11176/2965/54815/3720/2033/23512/64425/2068/3066/3065/2071/1107/54790/10849/2968/57504/84172/2967/22823/6908/23411/60/25942/8726/23378/10284/53615/1022/10919/121536/9533/9188 84 Rotavirus_C R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 95/1879 182/10654 1.2294220526558083e-26 1.1840280076346707e-25 6.201861852668571e-26 1912/23165/23468/7150/5903/55706/7175/55143/5241/9631/5468/1788/9112/8535/51564/1786/6045/9212/3619/4869/80012/10274/348995/79023/57122/23636/10735/8517/3183/332/10762/5885/23511/4306/53371/1655/5970/4792/3190/9759/9612/1911/6790/641/5111/2099/23279/4927/9688/79902/2494/9656/9883/1387/84733/10521/1616/1789/23225/2908/2033/23512/165918/8243/9126/57332/7428/3066/3065/7157/1107/6256/8086/7329/8924/672/115426/7158/10155/367/9972/5914/25942/8021/6294/6396/648/129401/7703/11315/55746/4791/8480/6015/4193 95 Rotavirus_C R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 44/1879 51/10654 1.4485351547486256e-26 1.3844015372101368e-25 7.251405395005172e-26 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/5694/5693/5721/5696/5691 44 Rotavirus_C R-HSA-674695 RNA Polymerase II Pre-transcription Events 59/1879 84/10654 2.4357606169736285e-26 2.310282039735593e-25 1.2101107371408058e-25 85403/2963/6917/5434/5440/902/6830/5430/5436/9646/404672/79577/6749/5441/5438/5431/7469/5435/4686/5433/4331/8148/2966/9150/2962/4298/54623/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/23168/55677/6881/2967/27125/51616/6908/11198/904/7936/6829/51497/4300/1022/5432/22916/8178/55840/6877/80349/123169/25920 59 Rotavirus_C R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 78/1879 134/10654 3.531553056150642e-26 3.324439418271131e-25 1.7413197894593194e-25 5295/8454/1147/5718/5689/3725/8945/5684/6464/5720/4790/6885/5682/4772/5700/122706/7321/5707/5690/5717/4214/9491/6500/23198/143471/5706/5705/10197/8517/7316/10213/5709/5695/7335/5970/4792/5714/9861/7322/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/10454/5702/5719/5704/6233/2885/5716/2353/7311/5296/808/3845/7334/5694/3265/3551/801/5693/5721/5696/997/5691/7314/805 78 Rotavirus_C R-HSA-2990846 SUMOylation 96/1879 188/10654 5.983917905193037e-26 5.590944192016181e-25 2.928500278817959e-25 1912/23165/23468/7150/5903/55706/7175/55143/5241/9631/5468/1788/9112/8535/51564/1786/6045/9212/3619/4869/80012/10274/348995/79023/57122/23636/10735/8517/3183/332/10762/5885/23511/4306/53371/1655/5970/4792/3190/9759/9612/1911/6790/641/5111/2099/23279/4927/9688/79902/2494/9656/9883/1387/84733/10521/1616/1789/23225/2908/59343/2033/23512/165918/8243/9126/57332/7428/3066/3065/7157/1107/6256/8086/7329/8924/672/115426/7158/10155/367/9972/5914/25942/8021/6294/6396/648/129401/7703/11315/55746/4791/8480/6015/4193 96 Rotavirus_C R-HSA-69002 DNA Replication Pre-Initiation 59/1879 85/10654 6.616927477065806e-26 6.136587556508436e-25 3.214304731549315e-25 5718/4172/6118/5689/5684/5720/8318/5682/5700/122706/5707/5690/5717/9491/23198/4173/143471/5706/5705/10197/7316/10213/5709/4174/5695/5714/5426/4171/9861/5715/4998/6119/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/4175/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/4176/7314 59 Rotavirus_C R-HSA-8948751 Regulation of PTEN stability and activity 52/1879 69/10654 9.253291179450223e-26 8.518470997552704e-25 4.461919817954713e-25 5718/5689/5684/5720/5682/5700/122706/5707/10273/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/4734/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5728/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/23608/5691/7314 52 Rotavirus_C R-HSA-113418 Formation of the Early Elongation Complex 33/1879 33/10654 1.0726627951122663e-25 9.73169434406201e-25 5.097398332226864e-25 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/2967/7936/6829/51497/1022/5432/22916/25920 33 Rotavirus_C R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 33/1879 33/10654 1.0726627951122663e-25 9.73169434406201e-25 5.097398332226864e-25 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/2967/7936/6829/51497/1022/5432/22916/25920 33 Rotavirus_C R-HSA-5663202 Diseases of signal transduction 151/1879 377/10654 1.3547742729470006e-25 1.2202715034026222e-24 6.391702931056277e-25 5295/8454/4000/1147/5718/27044/818/5689/2963/5434/5440/5684/11052/6464/8841/5720/3667/71/79718/8087/79885/142678/5682/1499/2648/10018/9734/55869/55750/5700/139285/122706/5707/5430/51564/3674/5436/5690/9530/5717/9491/6500/23198/409/10533/10013/143471/23385/5706/5705/5441/6199/10197/2260/5438/5431/2100/5435/4686/7316/10213/5709/83933/9978/5433/9611/5695/9759/9612/5714/2099/6934/4609/7415/9861/10014/5715/2962/22938/5519/8850/5711/2932/2261/5701/867/5688/1387/5437/5687/5685/6907/5683/5698/5708/3320/5692/5686/5713/324/2335/2033/408/55294/5728/5699/8312/5529/5710/11064/5439/5702/3066/3065/5719/5704/83464/6233/2885/5716/56829/8660/7311/5518/1956/60/4254/5296/9444/808/3845/55851/51107/5694/3265/801/4763/4851/5432/22916/5693/5663/5721/5696/5691/5245/7529/7314/4193/805/5515 151 Rotavirus_C R-HSA-5358346 Hedgehog ligand biogenesis 50/1879 65/10654 1.5665575187250404e-25 1.4009500096026791e-24 7.338085219290978e-25 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/5034/7314 50 Rotavirus_C R-HSA-5621481 C-type lectin receptors (CLRs) 80/1879 142/10654 1.644819659992157e-25 1.4605065349717594e-24 7.650038433558148e-25 8454/1147/5718/5689/8945/5684/5720/4790/6885/5682/4772/5700/122706/7321/5707/5690/9039/5717/9491/6500/23198/143471/5706/5705/841/10197/8517/7316/10213/5709/5695/9020/7335/5970/4792/5714/9861/5566/7322/5715/5711/5701/5688/1387/5687/23291/5685/5683/5698/5708/5692/5686/5713/2033/5699/5710/10454/5702/9040/5719/5704/6233/5716/7311/5971/808/3845/7334/5694/3265/3551/801/5693/5721/5696/997/5691/4791/7314/805 80 Rotavirus_C R-HSA-168325 Viral Messenger RNA Synthesis 39/1879 43/10654 1.7286337788462062e-25 1.5241193599404578e-24 7.9832382818471935e-25 23165/2963/5434/5440/5903/55706/7175/9631/5430/5436/348995/79023/57122/5441/23636/5438/10762/5431/23511/5435/5433/53371/23279/4927/9688/79902/2962/9883/5437/23225/5439/8086/9972/8021/6396/129401/5432/55746/8480 39 Rotavirus_C R-HSA-5689880 Ub-specific processing proteases 105/1879 220/10654 3.3643539070063247e-25 2.9455741899104325e-24 1.5428726419322343e-24 9960/5718/5689/10600/23032/5684/8295/5720/23326/7186/6885/6314/5682/2648/93624/5700/10474/122706/5707/991/8237/5690/55611/2625/9817/5717/9491/23198/63967/409/6478/1080/3091/9101/143471/5706/5705/57695/55031/27005/10197/8517/64750/7416/8239/7316/10213/5709/993/5695/4792/5714/9100/1643/4609/9861/5715/64426/5711/5701/5688/5687/6502/9099/5685/5683/5698/5708/5692/5686/5713/408/5728/5699/8312/5710/10454/5702/219333/7157/9958/8313/63891/5719/57599/5704/6233/5716/7311/367/6881/51616/23770/8607/1540/29761/5694/7874/5693/154/5721/5696/5691/7314/4193 105 Rotavirus_C R-HSA-453279 Mitotic G1-G1/S phases 82/1879 149/10654 3.496046230921677e-25 3.0396179729957914e-24 1.5921321651054128e-24 8454/5718/4172/6118/5689/26271/894/1019/5684/5720/902/8318/5682/5700/5707/5690/5717/9491/6500/898/5925/4173/5706/5705/10197/4149/7316/10213/5709/4174/891/993/5695/4331/983/5714/5111/5426/4171/4609/9861/5715/5519/4998/6119/5711/5928/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/595/5699/4175/5710/5702/3065/5520/5719/5704/6233/5716/7311/5518/5694/7465/1022/1859/5693/5721/5696/5691/4176/7314/5515 82 Rotavirus_C R-HSA-5696398 Nucleotide Excision Repair 68/1879 111/10654 8.61277382431754e-25 7.436684708996938e-24 3.8952871815243754e-24 9318/6118/6917/5434/5440/902/2074/27339/5430/83444/5436/5982/404672/9557/5441/7336/86/5438/5431/8450/5435/54778/7316/9978/5433/4331/64708/5111/5426/1643/2966/10980/6119/5437/79913/1161/1642/54617/2965/5985/10920/2033/2068/5439/10987/2071/7329/6233/2873/2968/7311/2967/56949/60/8533/8607/7334/7874/57461/5424/1022/5432/8178/50813/7314/51138/8451/7528 68 Rotavirus_C R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 41/1879 48/10654 1.7767467846207756e-24 1.523621215304939e-23 7.980629032579259e-24 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/22916/8178/25920 41 Rotavirus_C R-HSA-1257604 PIP3 activates AKT signaling 117/1879 264/10654 1.9260101242406764e-24 1.640384133026753e-23 8.592225616913293e-24 5295/1912/1147/5718/5689/27161/3725/5684/8841/5720/3667/5682/23035/5468/23186/5700/122706/5707/2146/5978/9112/9219/8535/10273/51564/6045/5690/57690/5717/9491/23198/27327/80012/5931/143471/5706/5705/6199/10197/192670/2260/2100/7316/10213/5709/5695/1911/4734/5714/2099/1108/9861/10014/5715/5519/5711/5928/2932/2261/5701/5688/84733/5687/57459/5685/5683/5698/5708/5692/54815/5686/5713/23512/57332/5728/5699/5529/5710/5702/192669/3066/3065/7157/1107/23028/5719/3654/23112/5704/6233/2885/5716/8660/57504/7311/5518/1386/1956/4254/5296/4343/8726/648/5694/23466/26523/7874/53615/5693/5721/5696/23608/5691/7314/6015/4193/5515 117 Rotavirus_C R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 55/1879 79/10654 2.464203002668737e-24 2.0845825400954452e-23 1.0918908041697177e-23 9318/6118/6917/5434/5440/902/2074/27339/5430/5436/5982/404672/5441/5438/5431/8450/5435/7316/9978/5433/4331/64708/5111/5426/2966/10980/6119/5437/1161/1642/2965/5985/10920/2033/2068/5439/10987/2071/6233/2873/2968/7311/2967/56949/8533/7874/57461/5424/1022/5432/8178/50813/7314/51138/8451 55 Rotavirus_C R-HSA-4086400 PCP/CE pathway 60/1879 92/10654 4.223831312014107e-24 3.5491522165380283e-23 1.8590228946554495e-23 57154/5718/5689/1173/5684/5720/5682/5700/122706/5707/1856/5690/5717/9491/23198/409/143471/5706/5705/10197/64750/7316/10213/5709/5695/5216/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/1855/5716/1857/163/7311/1213/387/1211/5694/5693/5721/5696/5691/7314 60 Rotavirus_C R-HSA-3858494 Beta-catenin independent WNT signaling 79/1879 146/10654 1.1505604986707818e-23 9.603344962238792e-23 5.0301697591010314e-23 57154/5718/5689/27161/51176/1173/5684/5720/6885/5682/1499/4772/5700/122706/5707/1856/5690/57690/5717/9491/23198/27327/409/143471/5706/5705/10197/192670/64750/7316/10213/5709/5695/5216/83439/5714/6934/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/192669/5719/23112/5704/6233/1855/6932/5716/1857/163/7311/1213/387/1211/4343/808/3845/5694/26523/801/5693/5721/5696/5691/7314/805 79 Rotavirus_C R-HSA-167169 HIV Transcription Elongation 39/1879 46/10654 4.302798898309414e-23 3.5209831507734547e-22 1.8442681208440073e-22 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/22916/8178/25920 39 Rotavirus_C R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 39/1879 46/10654 4.302798898309414e-23 3.5209831507734547e-22 1.8442681208440073e-22 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/22916/8178/25920 39 Rotavirus_C R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 39/1879 46/10654 4.302798898309414e-23 3.5209831507734547e-22 1.8442681208440073e-22 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/4686/5433/4331/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/22916/8178/25920 39 Rotavirus_C R-HSA-9006925 Intracellular signaling by second messengers 125/1879 305/10654 2.349157999450999e-22 1.9098349450082145e-21 1.0003591480915736e-21 5295/1912/1147/5718/818/5689/27161/3725/3838/5684/8841/5720/3667/5682/23035/5468/5575/23186/5700/122706/5707/2146/5978/9112/9219/8535/10273/51564/6045/5690/57690/5717/9491/23198/27327/80012/5931/143471/5706/5705/6199/10197/192670/2260/5573/2100/7316/10213/5709/5695/1911/4734/5714/2099/1108/9861/5566/10014/5715/5519/5711/5928/2932/2261/5701/5688/84733/5687/57459/5685/5683/5698/5708/5692/54815/5686/5713/23512/57332/5728/5699/5529/5710/5702/192669/3066/3065/7157/1107/23028/5719/3654/23112/5704/6233/2885/5716/8660/57504/7311/5518/1386/1956/4254/5296/4343/8726/808/648/5694/23466/26523/7874/801/53615/5693/5721/5696/23608/5691/7314/6015/4193/805/5515 125 Rotavirus_C R-HSA-3247509 Chromatin modifying enzymes 116/1879 274/10654 3.3272190844707724e-22 2.6703065985624403e-21 1.3986892642545825e-21 55904/9643/84678/54014/9070/84661/1019/8295/8841/23326/55167/11091/4790/79718/64769/51742/79595/80314/6597/6314/2648/23186/55869/93624/10474/2146/5978/1788/9112/9219/8085/6839/25855/5929/5931/8520/6598/79813/6599/86/7403/8819/83933/54556/54496/9611/56970/2874/10856/5970/11143/9612/63976/6603/10933/1108/5926/64426/79685/8850/55352/5928/10524/1387/57459/6907/8289/54815/2033/23512/6605/221656/55929/595/6944/8473/3066/3065/1107/79084/23028/23135/10943/10498/23067/9757/57504/6881/58508/23030/57634/1386/51317/10419/60/8607/9739/8726/3054/10902/3276/6601/56979/10284/6187/53615/10362/55257/4297/10765/4791/55193/8089/10919/121536/55170 116 Rotavirus_C R-HSA-4839726 Chromatin organization 116/1879 274/10654 3.3272190844707724e-22 2.6703065985624403e-21 1.3986892642545825e-21 55904/9643/84678/54014/9070/84661/1019/8295/8841/23326/55167/11091/4790/79718/64769/51742/79595/80314/6597/6314/2648/23186/55869/93624/10474/2146/5978/1788/9112/9219/8085/6839/25855/5929/5931/8520/6598/79813/6599/86/7403/8819/83933/54556/54496/9611/56970/2874/10856/5970/11143/9612/63976/6603/10933/1108/5926/64426/79685/8850/55352/5928/10524/1387/57459/6907/8289/54815/2033/23512/6605/221656/55929/595/6944/8473/3066/3065/1107/79084/23028/23135/10943/10498/23067/9757/57504/6881/58508/23030/57634/1386/51317/10419/60/8607/9739/8726/3054/10902/3276/6601/56979/10284/6187/53615/10362/55257/4297/10765/4791/55193/8089/10919/121536/55170 116 Rotavirus_C R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 53/1879 80/10654 6.447333571896322e-22 5.1414405299453475e-21 2.6930531782040957e-21 3839/23165/201626/3837/3838/5903/55706/7175/9631/2316/3841/348995/79023/57122/23636/8638/25820/7706/10762/9470/23511/7316/53371/4734/23279/4927/9688/79902/3840/9883/6059/23225/1981/1973/8086/7324/3836/9246/51191/6233/7311/9972/7318/5610/8021/9775/6396/129401/7334/55746/5495/8480/7314 53 Rotavirus_C R-HSA-2408522 Selenoamino acid metabolism 67/1879 118/10654 8.041652737658202e-22 6.37224634654941e-21 3.3377412761899134e-21 6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6128/51121/6132/6147/6129/6217/191/6222/6176/6152/6136/6125/6224/6146/6141/6202/6232/6134/6169/6160/6155/6175/6218/6209/6193/6210/6229/11224/6205/6165/6130/6204/6228/23521/6156/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/6133/6230 67 Rotavirus_C R-HSA-351202 Metabolism of polyamines 44/1879 59/10654 1.134227362032591e-21 8.931148787828954e-21 4.678077765947064e-21 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/5694/5693/5721/5696/5691 44 Rotavirus_C R-HSA-202403 TCR signaling 67/1879 119/10654 1.5293057011867755e-21 1.1966817111786519e-20 6.268141130522113e-21 5295/8454/1147/5718/5689/8945/5684/5720/4790/6885/5682/5700/122706/7321/5707/5690/5717/9491/6500/23198/143471/5706/5705/10197/8517/7316/10213/5709/5695/7335/5970/4792/5714/9861/7322/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5728/5699/5710/5702/5719/5704/6233/5716/7311/5296/7334/5694/3551/5693/5721/5696/997/5691/7314 67 Rotavirus_C R-HSA-3700989 Transcriptional Regulation by TP53 139/1879 365/10654 3.455570165471414e-21 2.6871887249504414e-20 1.407532012480347e-20 834/6118/27161/3725/9891/2963/6917/5434/5440/902/64769/7531/5430/10111/9219/8445/7532/10971/5436/9997/9212/57690/7832/4869/5982/404672/27327/898/5931/7533/6749/545/472/5441/79813/192670/7534/332/5438/580/5431/7469/5435/7316/5433/891/80196/4331/983/6790/641/5111/1108/1643/8148/2966/8797/9150/2962/9656/5519/6119/5928/1432/10524/1387/4683/5437/8812/57459/23019/1616/9099/2177/2965/5985/54815/51755/2033/10128/5728/905/2068/5439/1111/192669/3066/3065/2071/7157/1107/55215/91875/6827/23112/10498/6233/2968/672/55571/5932/1025/2353/604/7311/6881/2967/51616/5518/1386/6908/10419/4343/11198/5600/904/4697/3276/7936/6829/29883/26523/51497/7874/5052/1020/53615/1022/8795/5432/8178/83695/10919/6877/7529/7314/4193/5515/25920 139 Rotavirus_C R-HSA-1169408 ISG15 antiviral mechanism 49/1879 72/10654 3.8717230926189966e-21 2.992220562937644e-20 1.5673057093577874e-20 3839/23165/3837/3838/5903/55706/7175/9631/3841/348995/79023/57122/23636/25820/7706/10762/9470/23511/7316/53371/4734/23279/4927/9688/79902/3840/9883/23225/1981/1973/8086/7324/3836/9246/51191/6233/7311/9972/7318/5610/8021/9775/6396/129401/7334/55746/5495/8480/7314 49 Rotavirus_C R-HSA-5619084 ABC transporter disorders 51/1879 77/10654 3.940395690766214e-21 3.0266106778155214e-20 1.5853190283160164e-20 5718/5689/5684/5720/5682/5700/122706/5707/79139/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Rotavirus_C R-HSA-4570464 SUMOylation of RNA binding proteins 38/1879 47/10654 4.364397867717214e-21 3.33184520145241e-20 1.7451988906211968e-20 1912/23165/5903/55706/7175/9631/8535/6045/80012/348995/79023/57122/23636/3183/10762/23511/53371/3190/1911/23279/4927/9688/79902/9883/84733/23225/57332/8086/7329/9972/8021/6396/648/129401/7703/55746/8480/6015 38 Rotavirus_C R-HSA-73863 RNA Polymerase I Transcription Termination 30/1879 32/10654 6.98865094009262e-21 5.3029036224217944e-20 2.7776264980400014e-20 5434/5440/902/9015/79101/9014/30834/25885/404672/221830/5441/51082/5435/7270/4331/9013/7343/2966/5437/2965/64425/2068/2071/10849/2968/84172/2967/6908/1022/9533 30 Rotavirus_C R-HSA-68877 Mitotic Prometaphase 92/1879 200/10654 8.184336891792537e-21 6.172764932845937e-20 3.233254206459575e-20 55839/84617/79682/5903/54908/55143/64151/22981/7531/55869/1783/1058/11190/991/401541/203068/79019/7532/1454/80152/10382/9212/3619/79172/10274/121441/7277/348995/23421/79023/10381/57122/64105/10735/7278/6232/332/1780/10051/5885/1781/891/5501/4085/983/1639/23279/55166/10121/79902/9702/5566/54821/5519/2491/699/7846/113457/7283/347733/3320/80097/1060/91687/8243/9126/10426/23397/5529/11064/51143/10540/81027/10733/85378/4751/7514/9184/5518/10383/5347/84790/6396/1453/27229/64946/10726/55746/10592/7280/5515/1778 92 Rotavirus_C R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 60/1879 102/10654 9.593528276819661e-21 7.192273893759411e-20 3.767266382892309e-20 8454/7124/1147/5718/5689/8945/5684/5720/7186/5682/5700/122706/5707/5690/9039/5717/9491/6500/23198/143471/5706/5705/10197/7316/10213/5709/5695/9020/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5971/5694/5693/5721/5696/5691/4791/7314 60 Rotavirus_C R-HSA-446652 Interleukin-1 family signaling 73/1879 140/10654 1.0525150414479029e-20 7.8437430469808e-20 4.108501696879972e-20 8454/1147/5778/5718/834/5689/8945/1326/5684/351/5720/4790/6885/5682/5783/5700/122706/5707/5690/8878/5717/9491/6500/23198/143471/5706/5705/10197/8517/7316/10213/5709/9978/5695/79155/7335/5970/4792/4793/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/10454/5702/5719/3654/5704/6233/5716/7311/7334/5694/3551/5693/5721/5696/5691/4791/7314 73 Rotavirus_C R-HSA-157118 Signaling by NOTCH 102/1879 235/10654 1.2912562103766902e-20 9.565992753796545e-20 5.0106049147597514e-20 8454/5718/23286/5689/27161/3725/5684/8841/5720/79718/79885/142678/5682/2648/9734/55869/5700/5707/51564/4904/487/5690/57690/5717/9491/6500/27327/409/3091/51548/10013/23385/5706/5705/10197/192670/7534/488/7316/10213/5709/83933/9978/9611/5695/9759/9612/5714/4609/9861/10014/5715/22938/8850/5711/5087/5701/5688/1387/5687/5685/6907/5683/5698/5708/59/5692/5686/5713/2033/408/595/55294/5699/5710/5702/192669/3066/3065/7157/83737/861/5719/23112/5704/83464/6233/5716/7311/1956/4343/55851/51107/5694/26523/4851/5693/5663/5721/5696/5691/7314 102 Rotavirus_C R-HSA-72086 mRNA Capping 28/1879 29/10654 1.620475377841749e-20 1.1934324547399235e-19 6.251121736194487e-20 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/4686/5433/4331/2966/8731/2962/5437/2965/2068/5439/2071/2968/2967/6829/1022/5432/22916 28 Rotavirus_C R-HSA-71291 Metabolism of amino acids and derivatives 139/1879 372/10654 2.624236562574217e-20 1.9213708633584328e-19 1.0064015872476067e-19 5161/5718/6470/5689/6138/6144/38/6203/5684/6227/9349/4736/29920/5720/6206/6194/6234/6191/6128/5682/51121/6132/6147/6129/5160/6217/5700/3028/122706/5707/191/25828/6222/1743/6176/6152/5690/6136/594/6125/5717/9491/23198/1737/6224/6146/6141/143471/6202/5706/5705/10197/6232/6134/6169/6160/6155/10213/5709/6175/6218/5695/5092/6209/5714/84706/6193/6210/6229/11224/6205/6165/9861/6130/5715/5711/6204/5701/5688/6228/23521/23464/5687/1152/5832/5685/5683/5698/5708/5692/5686/5713/5831/5162/6156/5699/6143/5710/6181/6124/5702/26227/64087/6207/1159/5719/6139/6520/5704/6233/5716/7311/6223/25873/1738/548596/3921/6188/6189/5625/6135/6201/5860/1734/5694/9045/6187/6168/5693/6208/2746/5721/6137/5696/5691/6122/6133/593/6230 139 Rotavirus_C R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 45/1879 65/10654 5.518029086419862e-20 4.016611869882365e-19 2.1038752269520037e-19 6118/6917/5434/5440/902/2074/27339/5430/5436/5982/404672/5441/5438/5431/8450/5435/7316/9978/5433/4331/5111/5426/2966/6119/5437/1161/1642/2965/5985/2033/2068/5439/2071/6233/2968/7311/2967/56949/7874/57461/5424/1022/5432/7314/8451 45 Rotavirus_C R-HSA-1236974 ER-Phagosome pathway 52/1879 83/10654 6.896648238981469e-20 4.991100344049016e-19 2.6143059646397657e-19 1147/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/8517/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/7097/3551/5693/5721/5696/5691/7314 52 Rotavirus_C R-HSA-6782135 Dual incision in TC-NER 45/1879 66/10654 1.4410298914300907e-19 1.036878979350847e-18 5.43110479347215e-19 6118/6917/5434/5440/902/2074/27339/5430/5436/5982/404672/5441/5438/5431/8450/5435/7316/9978/5433/4331/5111/5426/2966/6119/5437/1161/1642/2965/5985/2033/2068/5439/2071/6233/2968/7311/2967/56949/7874/57461/5424/1022/5432/7314/8451 45 Rotavirus_C R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 40/1879 55/10654 3.770799964644445e-19 2.6977380318484828e-18 1.4130576709614972e-18 3303/84617/5241/1783/10382/10294/7277/10381/3337/7278/1780/4306/1781/3305/1639/2289/10121/7846/113457/2908/347733/3320/51143/3301/10540/81027/10963/3326/3306/367/10383/84790/3304/3312/55466/7280/2288/10728/829/1778 40 Rotavirus_C R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 26/1879 27/10654 4.967160313549535e-19 3.5134941878892754e-018 1.840345450693643e-18 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/5433/4331/2966/8731/2962/5437/2965/2068/5439/2071/2968/2967/6829/1022/5432 26 Rotavirus_C R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 26/1879 27/10654 4.967160313549535e-19 3.5134941878892754e-018 1.840345450693643e-18 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/5433/4331/2966/8731/2962/5437/2965/2068/5439/2071/2968/2967/6829/1022/5432 26 Rotavirus_C R-HSA-168253 Host Interactions with Influenza Factors 34/1879 42/10654 5.017723132392047e-19 3.529319866154406e-18 1.8486348382497014e-18 3839/23165/3837/3838/5903/55706/7175/9631/8106/3841/348995/79023/57122/23636/10762/23511/293/53371/23279/4927/9688/79902/3840/9883/23225/8086/3836/9972/5610/8021/6396/129401/55746/8480 34 Rotavirus_C R-HSA-191859 snRNP Assembly 39/1879 53/10654 5.29141226927214e-19 3.680471200627066e-18 1.9278069261734167e-18 23165/6635/6606/5903/6633/6632/55706/7175/9631/25929/6637/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/51808/23225/79084/8086/6636/9972/6634/10419/8021/6396/129401/55746/22916/8480/6628 39 Rotavirus_C R-HSA-194441 Metabolism of non-coding RNA 39/1879 53/10654 5.29141226927214e-19 3.680471200627066e-18 1.9278069261734167e-18 23165/6635/6606/5903/6633/6632/55706/7175/9631/25929/6637/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/51808/23225/79084/8086/6636/9972/6634/10419/8021/6396/129401/55746/22916/8480/6628 39 Rotavirus_C R-HSA-168276 NS1 Mediated Effects on Host Pathways 33/1879 40/10654 5.488823411599973e-19 3.796688901283517e-18 1.988681003446806e-18 3839/23165/3837/3838/5903/55706/7175/9631/8106/3841/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/3840/9883/23225/8086/3836/9972/5610/8021/6396/129401/55746/8480 33 Rotavirus_C R-HSA-2500257 Resolution of Sister Chromatid Cohesion 66/1879 126/10654 5.599542642250633e-19 3.851993070383403e-18 2.0176489682603497e-18 55839/84617/79682/5903/54908/55143/55869/1783/1058/991/401541/79019/80152/10382/9212/3619/79172/10274/7277/348995/23421/79023/10381/57122/64105/10735/7278/6232/332/1780/5885/1781/891/5501/4085/983/23279/55166/79902/54821/5519/2491/699/7846/113457/347733/1060/91687/8243/9126/5529/51143/81027/7514/9184/5518/10383/5347/84790/6396/64946/10726/55746/7280/5515/1778 66 Rotavirus_C R-HSA-167172 Transcription of the HIV genome 47/1879 73/10654 8.199528125123384e-19 5.609731810193702e-18 2.9383411112751612e-18 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/4686/5433/4331/8148/2966/8731/9150/2962/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/6881/2967/51616/6908/11198/904/7936/6829/51497/1022/5432/22916/8178/6877/25920 47 Rotavirus_C R-HSA-5619115 Disorders of transmembrane transporters 81/1879 176/10654 1.7430120078773664e-18 1.186005996664382e-17 6.212222430821506e-18 5718/23165/5689/6507/5684/5903/5720/55706/7175/5682/9631/5700/122706/5707/79139/5690/5717/9491/23198/1080/348995/143471/79023/5706/57122/5705/23636/10197/10762/23511/7316/10213/5709/5695/53371/5714/23279/4927/9688/7415/9861/79902/5715/5711/9883/5701/5688/5687/23225/5685/5683/682/5698/5708/5692/5686/5713/5699/5710/5702/8086/5719/6520/5704/6233/5716/7311/9972/8021/6396/129401/5694/9197/55746/5693/5721/5696/5691/6566/8480/7314 81 Rotavirus_C R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 29/1879 33/10654 2.2914056080182673e-18 1.5423870006660595e-17 8.078922998276064e-18 23165/3303/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/7514/9972/8021/6396/129401/3304/55746/8480 29 Rotavirus_C R-HSA-180746 Nuclear import of Rev protein 29/1879 33/10654 2.2914056080182673e-18 1.5423870006660595e-17 8.078922998276064e-18 23165/3837/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/9972/8021/6396/129401/1104/55746/8480 29 Rotavirus_C R-HSA-109581 Apoptosis 81/1879 178/10654 4.073877981532694e-18 2.727537557689269e-17 1.4286664691780852e-17 4000/5718/5689/3837/5684/5720/7186/22985/1612/5682/1499/4976/10018/7531/5700/122706/5707/7532/10971/5690/10059/5717/9491/23198/63967/7533/143471/5706/5705/841/10197/7534/9500/7316/10213/5709/5695/5339/5714/8797/9861/5715/5711/5701/5688/5687/1832/836/5685/5683/5698/5708/5692/5686/708/5713/324/5699/5710/5702/7157/5719/4001/3836/5704/6233/6709/5716/7311/840/8772/7431/5694/8743/8795/5693/5721/5696/5691/7529/7314 81 Rotavirus_C R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 23/1879 23/10654 4.160385619245218e-18 2.77063978473139e-17 1.4512431359405212e-17 2963/5434/5440/5430/5436/5441/5438/5431/7469/5435/4686/5433/9150/2962/5437/5439/6827/7936/6829/51497/5432/22916/25920 23 Rotavirus_C R-HSA-69618 Mitotic Spindle Checkpoint 60/1879 112/10654 5.382538465085312e-18 3.5655757451252965e-17 1.8676254323297966e-17 55839/79682/5903/11065/54908/55143/246184/1783/1058/7321/991/401541/79019/80152/8697/9212/3619/79172/348995/23421/79023/57122/64105/6232/332/1780/8881/1781/5501/4085/23279/55166/51433/79902/54821/5519/2491/699/1060/91687/5529/51143/51529/7324/64682/29945/10393/51434/7514/9184/5518/5347/29882/6396/64946/10726/55746/996/5515/1778 60 Rotavirus_C R-HSA-73894 DNA Repair 124/1879 334/10654 5.8935609731540386e-18 3.883546493888872e-17 2.034176446689732e-17 9318/8467/51750/7014/6118/25913/3838/6917/5434/5440/902/2074/27339/5430/10111/83444/56852/5436/7320/7520/51720/2956/5982/63967/404672/9557/7013/5531/51548/545/472/5441/7706/7336/86/5438/580/5431/5591/29086/8450/5435/54778/7316/9978/5433/9031/4331/64708/8314/26277/641/5111/5426/9100/1643/10459/2966/7415/10980/9656/6119/22976/10524/4683/5437/79913/1161/2177/1642/54617/2965/5985/10920/65057/25898/2033/165918/2068/5439/1111/10987/2071/7157/55215/7329/4255/9246/79728/8924/57599/6233/2873/2968/672/5932/7158/7311/6047/9025/7318/2967/79184/56949/23030/60/5536/8533/8607/7334/7874/57461/54386/5424/1022/5432/8178/83695/50813/57697/7314/51138/8451/7528 124 Rotavirus_C R-HSA-159227 Transport of the SLBP independent Mature mRNA 29/1879 34/10654 1.2960425970482194e-17 8.495525295834401e-17 4.449901008327587e-17 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/9972/8021/6396/129401/55746/22916/8480 29 Rotavirus_C R-HSA-177243 Interactions of Rev with host cellular proteins 30/1879 36/10654 1.3128385799553673e-17 8.560801573458957e-17 4.484092298860712e-17 23165/3837/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/7514/9972/8021/6396/129401/1104/55746/8480 30 Rotavirus_C R-HSA-5357801 Programmed Cell Death 81/1879 181/10654 1.405915874524522e-17 9.120241838884463e-17 4.7771234787498076e-17 4000/5718/5689/3837/5684/5720/7186/22985/1612/5682/1499/4976/10018/7531/5700/122706/5707/7532/10971/5690/10059/5717/9491/23198/63967/7533/143471/5706/5705/841/10197/7534/9500/7316/10213/5709/5695/5339/5714/8797/9861/5715/5711/5701/5688/5687/1832/836/5685/5683/5698/5708/5692/5686/708/5713/324/5699/5710/5702/7157/5719/4001/3836/5704/6233/6709/5716/7311/840/8772/7431/5694/8743/8795/5693/5721/5696/5691/7529/7314 81 Rotavirus_C R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 47/1879 77/10654 1.9300740342150767e-17 1.2455941705346783e-16 6.524341417883845e-17 1912/23165/5903/55706/7175/9631/8535/51564/6045/80012/10274/348995/79023/57122/23636/10735/10762/5885/23511/53371/1911/641/23279/4927/9688/79902/9656/9883/84733/23225/165918/8243/9126/57332/8086/7329/8924/672/9972/8021/6396/648/129401/7703/55746/8480/6015 47 Rotavirus_C R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 27/1879 31/10654 5.811623389077267e-17 3.712322695471805e-16 1.944490532435627e-16 23165/3837/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/3836/9972/8021/6396/129401/55746/8480 27 Rotavirus_C R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 27/1879 31/10654 5.811623389077267e-17 3.712322695471805e-16 1.944490532435627e-16 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/7514/9972/8021/6396/129401/55746/8480 27 Rotavirus_C R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 29/1879 35/10654 6.288648516193673e-17 3.9966436255200395e-16 2.0934159901622537e-16 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/9972/8021/6396/129401/55746/22916/8480 29 Rotavirus_C R-HSA-5663220 RHO GTPases Activate Formins 67/1879 140/10654 1.364091792448063e-16 8.62546931386351e-16 4.517964841547811e-16 55839/84617/79682/5903/54908/71/55143/1783/1058/991/1856/401541/79019/80152/10382/9212/3619/79172/7277/348995/23421/79023/10381/57122/64105/7278/6232/332/1780/1781/5501/4085/5216/23279/55166/79902/54821/5519/2491/699/7846/113457/347733/752/1060/91687/5529/51143/998/81027/1855/1857/7514/9184/5518/10383/5347/387/60/84790/6396/64946/10726/55746/7280/5515/1778 67 Rotavirus_C R-HSA-201681 TCF dependent signaling in response to WNT 94/1879 233/10654 1.5032891252861368e-16 9.457879320895696e-16 4.953975800334637e-16 5718/9070/5689/51176/8945/5684/8295/857/5720/6597/5682/1499/5700/139285/122706/5707/1856/8085/1454/5690/5717/5929/9491/23198/79577/283149/9101/143471/5706/5705/10197/7534/64750/8452/7316/10213/5709/9978/5695/83439/5714/6934/4609/59349/9861/5715/5519/5711/2932/5701/10524/5688/1387/5687/607/5685/5683/5698/5708/5692/5686/5713/324/2033/5699/8312/5529/5710/5702/3065/8313/5719/57680/5704/6233/1855/6932/5716/1857/7514/90780/7311/26108/5518/8607/5694/5693/5721/5696/5691/7314/4221/123169/5515 94 Rotavirus_C R-HSA-6803529 FGFR2 alternative splicing 24/1879 26/10654 1.6359975100945963e-16 1.0241344413192171e-15 5.364349730468071e-16 2963/5434/5440/23543/5430/5436/3178/5441/5438/5431/5435/4686/5433/3185/2962/5437/4670/5439/7072/3187/7073/5432/22916/5725 24 Rotavirus_C R-HSA-167287 HIV elongation arrest and recovery 29/1879 36/10654 2.690271825203824e-16 1.6592218350518166e-15 8.690896277427962e-16 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/7469/5435/5433/9150/2962/5437/8812/905/5439/6827/1025/11198/904/7936/6829/51497/5432/8178/25920 29 Rotavirus_C R-HSA-167290 Pausing and recovery of HIV elongation 29/1879 36/10654 2.690271825203824e-16 1.6592218350518166e-15 8.690896277427962e-16 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/7469/5435/5433/9150/2962/5437/8812/905/5439/6827/1025/11198/904/7936/6829/51497/5432/8178/25920 29 Rotavirus_C R-HSA-176033 Interactions of Vpr with host cellular proteins 29/1879 36/10654 2.690271825203824e-16 1.6592218350518166e-15 8.690896277427962e-16 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/293/53371/292/23279/4927/9688/79902/9883/23225/8815/8086/3836/9972/8021/6396/129401/55746/8480 29 Rotavirus_C R-HSA-165054 Rev-mediated nuclear export of HIV RNA 28/1879 34/10654 2.9940815617753164e-16 1.8375441741875962e-15 9.624937115510951e-16 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/7514/9972/8021/6396/129401/1104/55746/8480 28 Rotavirus_C R-HSA-2980766 Nuclear Envelope Breakdown 36/1879 52/10654 3.025964843540528e-16 1.848052675176947e-15 9.679979961621305e-16 4000/23165/5903/55706/7175/9631/348995/79023/57122/23636/7443/10762/23511/891/53371/983/23279/4927/9688/79902/9883/23225/8815/9663/8086/2010/4001/23175/9972/5347/8021/6396/129401/55746/7112/8480 36 Rotavirus_C R-HSA-4615885 SUMOylation of DNA replication proteins 33/1879 45/10654 3.3644385594694103e-16 2.044794697308593e-15 1.0710501903676252e-15 23165/7150/5903/55706/7175/55143/9631/9212/3619/348995/79023/57122/23636/332/10762/23511/53371/6790/5111/23279/4927/9688/79902/9883/23225/8086/7329/9972/8021/6396/129401/55746/8480 33 Rotavirus_C R-HSA-195721 Signaling by WNT 119/1879 331/10654 4.764950265750964e-16 2.8819892428600036e-15 1.5095672593759729e-15 8454/57154/5718/9070/5689/27161/51176/8945/1173/5684/8295/857/5720/6885/6597/5682/1499/4772/5700/139285/122706/5707/1856/8085/1454/5690/57690/5717/5929/9491/6500/23198/27327/409/79577/283149/9101/143471/5706/5705/10197/192670/7534/64750/8452/7316/10213/5709/9978/5695/5216/83439/7477/5714/6934/4609/59349/9861/5715/5519/5711/2932/5701/10524/5688/1387/5687/607/5685/5683/5698/5708/5692/5686/5713/324/2033/5699/8312/5529/5710/5702/192669/3065/8313/5719/23112/57680/5704/6233/1855/6932/5716/1857/7514/90780/163/7311/26108/5518/1213/387/1211/8607/4343/808/3845/5694/26523/801/5693/5721/5696/5691/7314/4221/805/123169/5515 119 Rotavirus_C R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 31/1879 41/10654 6.285369921262885e-16 3.783309202606313e-15 1.9816728041228628e-15 23165/53981/5903/55706/7175/9631/29894/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/9972/8021/6396/129401/55746/22916/8480 31 Rotavirus_C R-HSA-180910 Vpr-mediated nuclear import of PICs 27/1879 33/10654 1.4163577828640534e-15 8.484593034190406e-15 4.444174760636138e-15 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8815/8086/3836/9972/8021/6396/129401/55746/8480 27 Rotavirus_C R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 44/1879 75/10654 1.6677092841562915e-15 9.942723922684177e-15 5.207934255786314e-15 10921/23165/5903/8683/6430/55706/7175/9631/6428/348995/79023/57122/23636/10762/23511/4686/9785/53371/11338/4116/7307/6429/23279/4927/9688/79902/9883/51213/10250/23225/10189/9295/10482/8086/9972/8021/9775/6396/129401/6427/6426/55746/22916/8480 44 Rotavirus_C R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 31/1879 42/10654 1.995908300943868e-15 1.1843019871003427e-14 6.203296939326665e-15 23165/53981/5903/55706/7175/9631/29894/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/9972/8021/6396/129401/55746/22916/8480 31 Rotavirus_C R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 47/1879 84/10654 2.322437669415438e-15 1.3715528123151548e-14 7.184104607973276e-15 9318/6118/902/83444/5982/404672/9557/7336/86/8450/54778/7316/9978/4331/64708/5111/5426/1643/2966/10980/6119/79913/1642/54617/2965/5985/10920/2068/10987/2071/7329/6233/2873/2968/7311/2967/60/8533/8607/7334/5424/1022/50813/7314/51138/8451/7528 47 Rotavirus_C R-HSA-1236975 Antigen processing-Cross presentation 52/1879 99/10654 2.6759050401830073e-15 1.5728793945113263e-14 8.238640178077655e-15 1147/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/8517/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/7097/3551/5693/5721/5696/5691/7314 52 Rotavirus_C R-HSA-203927 MicroRNA (miRNA) biogenesis 22/1879 24/10654 4.5613220459027e-15 2.668586542743075e-14 1.3977883101807094e-14 27161/6895/5434/5440/5430/5436/5441/192670/5438/5431/5435/54487/5433/5437/5439/192669/5901/29102/144233/26523/5432/23405 22 Rotavirus_C R-HSA-4551638 SUMOylation of chromatin organization proteins 42/1879 71/10654 4.87227121368561e-15 2.8372481672252945e-14 1.4861321743579606e-14 1912/23165/23468/5903/55706/7175/9631/8535/6045/80012/348995/79023/57122/23636/10762/23511/53371/9759/1911/23279/4927/9688/79902/9883/84733/23225/23512/57332/3066/3065/1107/8086/7329/9972/8021/6396/648/129401/7703/55746/8480/6015 42 Rotavirus_C R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 27/1879 34/10654 5.7245920572263815e-015 3.3028521915425945e-14 1.730012540214424e-14 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/7469/5435/5433/9150/2962/5437/5439/6827/1025/11198/904/7936/6829/51497/5432/8178/25920 27 Rotavirus_C R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 27/1879 34/10654 5.7245920572263815e-015 3.3028521915425945e-14 1.730012540214424e-14 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/7469/5435/5433/9150/2962/5437/5439/6827/1025/11198/904/7936/6829/51497/5432/8178/25920 27 Rotavirus_C R-HSA-5683057 MAPK family signaling cascades 107/1879 294/10654 5.852197979480976e-15 3.3609870964725604e-14 1.760463226082399e-14 5718/818/5689/27161/3725/57554/5684/6464/6711/5720/3667/71/5682/5700/10642/122706/5707/3674/5690/57690/5717/9491/3315/23198/27327/409/143471/5706/5705/10197/3337/192670/2260/8452/7316/10213/5709/9978/5695/983/84078/5714/4609/9861/5566/5715/5519/5711/2261/5701/5688/5687/5685/54756/5683/5698/5708/5692/5686/5713/2335/408/5699/5529/5710/5702/192669/998/5719/9693/23112/1742/5704/6233/2885/6709/5716/8660/7514/7311/5518/1956/60/4254/5536/5896/399473/4343/808/3845/5694/3265/26523/801/200734/4763/8202/5693/5721/5696/5691/5245/7529/7314/161742/805/5515 107 Rotavirus_C R-HSA-72649 Translation initiation complex formation 37/1879 58/10654 6.716562009433115e-15 3.8397879615571965e-14 2.0112560114764865e-14 6203/6227/6206/6194/6234/6191/8666/6217/6222/8668/6224/26986/6202/6232/6218/6209/6193/6210/6229/6205/6204/8663/6228/1981/1973/6207/6233/1975/6223/8664/3921/6188/6189/6201/6187/6208/6230 37 Rotavirus_C R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 25/1879 30/10654 7.21631988805712e-15 4.106742045385234e-14 2.1510848278754004e-14 11065/7319/7321/65264/7320/10477/92912/7326/8239/7316/7317/54926/55236/3093/7322/7328/7324/6233/7327/7311/55284/27338/7874/997/7314 25 Rotavirus_C R-HSA-9018519 Estrogen-dependent gene expression 67/1879 150/10654 1.0286972289488194e-14 5.827732717845801e-14 3.05252857173191e-14 3727/27161/3725/2354/2963/3838/5434/5440/7764/5241/9687/5430/5436/5451/2625/57690/27327/10274/5441/10735/192670/200845/5438/5431/5885/5435/5433/865/1105/1655/2099/4609/2494/2962/8850/10524/1387/5437/3320/2033/8243/9126/595/8312/5439/192669/3065/861/23028/23112/10498/3326/1025/2353/23030/1386/6908/3169/4343/904/3276/26523/8202/5432/2288/10728/7528 67 Rotavirus_C R-HSA-72202 Transport of Mature Transcript to Cytoplasm 46/1879 84/10654 1.382268098747334e-14 7.795493962304785e-14 4.083229139495444e-14 10921/23165/53981/5903/8683/6430/55706/7175/9631/6428/29894/348995/79023/57122/23636/10762/23511/4686/9785/53371/11338/4116/7307/6429/23279/4927/9688/79902/9883/51213/10250/23225/10189/9295/10482/8086/9972/8021/9775/6396/129401/6427/6426/55746/22916/8480 46 Rotavirus_C R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 37/1879 59/10654 1.49739254596844e-14 8.406885504719673e-14 4.4034720610731094e-14 6203/6227/6206/6194/6234/6191/8666/6217/6222/8668/6224/26986/6202/6232/6218/6209/6193/6210/6229/6205/6204/8663/6228/1981/1973/6207/6233/1975/6223/8664/3921/6188/6189/6201/6187/6208/6230 37 Rotavirus_C R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 27/1879 35/10654 2.084154516455584e-14 1.1648935065189248e-13 6.101636577781151e-14 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/891/53371/983/23279/4927/9688/79902/9883/23225/8086/9972/8021/6396/129401/55746/8480 27 Rotavirus_C R-HSA-382556 ABC-family proteins mediated transport 52/1879 103/10654 2.2564817760104345e-14 1.2556067482511396e-13 6.576786650079536e-14 5718/5689/5684/5720/5682/5700/122706/5707/79139/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5825/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 52 Rotavirus_C R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 21/1879 23/10654 2.3944066087048876e-14 1.3264588823444777e-13 6.947905529683955e-14 11065/246184/7321/991/8697/8881/7316/891/983/51433/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 21 Rotavirus_C R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 25/1879 31/10654 3.103780120965839e-14 1.7043564523900133e-13 8.927308473507467e-14 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/6396/129401/55746/8480 25 Rotavirus_C R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 25/1879 31/10654 3.103780120965839e-14 1.7043564523900133e-13 8.927308473507467e-14 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/6396/129401/55746/8480 25 Rotavirus_C R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 22/1879 25/10654 3.1664342500051035e-14 1.7311684196534452e-13 9.067747817757663e-14 11065/246184/7321/991/8697/8881/7316/4085/51433/51529/7324/64682/29945/10393/4751/6233/51434/7311/9184/29882/7314/996 22 Rotavirus_C R-HSA-3232142 SUMOylation of ubiquitinylation proteins 28/1879 38/10654 5.0432785557562536e-14 2.745297718176882e-13 1.4379691259661997e-13 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/7428/8086/7329/9972/8021/6396/129401/55746/8480/4193 28 Rotavirus_C R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 36/1879 58/10654 5.41908013577041e-14 2.874867936434133e-13 1.5058371652921345e-13 8454/8841/79718/79885/142678/2648/9734/55869/51564/6500/10013/23385/7316/83933/9978/9611/9759/9612/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/83464/6233/7311/55851/51107/4851/5663/7314 36 Rotavirus_C R-HSA-2644603 Signaling by NOTCH1 in Cancer 36/1879 58/10654 5.41908013577041e-14 2.874867936434133e-13 1.5058371652921345e-13 8454/8841/79718/79885/142678/2648/9734/55869/51564/6500/10013/23385/7316/83933/9978/9611/9759/9612/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/83464/6233/7311/55851/51107/4851/5663/7314 36 Rotavirus_C R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 36/1879 58/10654 5.41908013577041e-14 2.874867936434133e-13 1.5058371652921345e-13 8454/8841/79718/79885/142678/2648/9734/55869/51564/6500/10013/23385/7316/83933/9978/9611/9759/9612/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/83464/6233/7311/55851/51107/4851/5663/7314 36 Rotavirus_C R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 36/1879 58/10654 5.41908013577041e-14 2.874867936434133e-13 1.5058371652921345e-13 8454/8841/79718/79885/142678/2648/9734/55869/51564/6500/10013/23385/7316/83933/9978/9611/9759/9612/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/83464/6233/7311/55851/51107/4851/5663/7314 36 Rotavirus_C R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 36/1879 58/10654 5.41908013577041e-14 2.874867936434133e-13 1.5058371652921345e-13 8454/8841/79718/79885/142678/2648/9734/55869/51564/6500/10013/23385/7316/83933/9978/9611/9759/9612/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/83464/6233/7311/55851/51107/4851/5663/7314 36 Rotavirus_C R-HSA-72702 Ribosomal scanning and start codon recognition 36/1879 58/10654 5.41908013577041e-14 2.874867936434133e-13 1.5058371652921345e-13 6203/6227/6206/6194/6234/6191/8666/6217/6222/8668/6224/6202/6232/6218/6209/6193/6210/6229/6205/6204/8663/6228/1981/1973/6207/6233/1975/6223/8664/3921/6188/6189/6201/6187/6208/6230 36 Rotavirus_C R-HSA-4085377 SUMOylation of SUMOylation proteins 26/1879 34/10654 9.236357856550346e-14 4.879291154599592e-13 2.5557410369224364e-013 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/7329/9972/8021/6396/129401/55746/8480 26 Rotavirus_C R-HSA-5617472 Activation of anterior HOX genes in hindbrain development during early embryogenesis 57/1879 122/10654 9.543604661461276e-14 4.999411312196452e-13 2.61865919581166e-13 9070/3725/5434/5440/3212/8841/11091/3214/4211/2146/5430/84962/8085/5436/5929/5931/5915/5441/3213/5438/5431/7403/5435/5433/9611/9935/10664/3200/3232/5928/5087/22976/1387/5437/3199/2033/23512/3211/5439/6256/3231/3198/3221/58508/23054/5914/8726/5080/5316/7703/5916/3201/8202/5432/1959/3233/7528 57 Rotavirus_C R-HSA-5619507 Activation of HOX genes during differentiation 57/1879 122/10654 9.543604661461276e-14 4.999411312196452e-13 2.61865919581166e-13 9070/3725/5434/5440/3212/8841/11091/3214/4211/2146/5430/84962/8085/5436/5929/5931/5915/5441/3213/5438/5431/7403/5435/5433/9611/9935/10664/3200/3232/5928/5087/22976/1387/5437/3199/2033/23512/3211/5439/6256/3231/3198/3221/58508/23054/5914/8726/5080/5316/7703/5916/3201/8202/5432/1959/3233/7528 57 Rotavirus_C R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 33/1879 51/10654 1.0791146985996712e-13 5.629381677694952e-13 2.9486335843315575e-13 6203/6227/6206/6194/6234/6191/8666/6217/6222/8668/6224/6202/6232/6218/6209/6193/6210/6229/6205/6204/8663/6228/6207/6233/6223/8664/3921/6188/6189/6201/6187/6208/6230 33 Rotavirus_C R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 23/1879 28/10654 1.6377529947684284e-13 8.508160786099886e-13 4.4565193961158807e-13 10694/84617/5204/10575/10382/5203/7277/10381/7278/7203/10576/908/6950/7846/113457/347733/81027/10574/10383/60/84790/22948/7280 23 Rotavirus_C R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs 59/1879 130/10654 1.7253100103193409e-13 8.925984020329813e-13 4.675372494253804e-13 5718/5689/5684/5720/902/5682/5700/122706/5707/5690/2625/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/865/5695/4331/10413/2623/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/83737/861/5719/5704/6233/5716/7311/6688/5694/1022/5693/5721/4297/5696/5691/7314 59 Rotavirus_C R-HSA-72165 mRNA Splicing - Minor Pathway 33/1879 52/10654 2.456075766826729e-13 1.2654349218382982e-12 6.628265985414996e-13 23451/2963/6635/5434/5440/6633/6632/5430/4904/5436/6637/23450/5441/5438/5431/5435/10594/4686/5433/9343/2962/5437/23020/5439/6636/6634/6427/6426/5432/22916/10992/10262/6628 33 Rotavirus_C R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 31/1879 47/10654 2.7900519571977815e-13 1.4316168239391896e-12 7.498716002304649e-13 8454/8841/79718/79885/2648/9734/55869/51564/6500/3091/10013/7316/83933/9978/9611/9759/9612/4609/10014/22938/8850/1387/6907/2033/55294/3066/3065/6233/7311/4851/7314 31 Rotavirus_C R-HSA-9022692 Regulation of MECP2 expression and activity 25/1879 33/10654 4.056554096250551e-13 2.0729819300023225e-12 1.0858144798986437e-12 818/27161/8841/2290/79718/9212/57690/27327/192670/9611/2874/9612/5566/6907/192669/3066/3065/4204/23112/25942/4343/808/26523/801/805 25 Rotavirus_C R-HSA-1980143 Signaling by NOTCH1 40/1879 73/10654 7.162245474325593e-13 3.645175338965708e-12 1.909319182928902e-12 8454/8841/79718/79885/142678/2648/9734/55869/51564/6500/409/3091/10013/23385/7316/83933/9978/9611/9759/9612/4609/10014/22938/8850/1387/6907/2033/408/55294/3066/3065/83737/83464/6233/7311/55851/51107/4851/5663/7314 40 Rotavirus_C R-HSA-8852135 Protein ubiquitination 42/1879 79/10654 7.496029181725576e-13 3.799606694542681e-12 1.99020932461753e-12 11065/7319/7321/79139/56852/65264/9646/7320/10477/92912/79577/7336/7326/5591/7323/8239/7316/7317/54926/55236/56254/5111/7415/3093/7322/54623/118424/7328/7324/6233/7327/23168/7311/55284/27338/7334/7874/997/6596/80349/7314/123169 42 Rotavirus_C R-HSA-8939211 ESR-mediated signaling 83/1879 223/10654 1.7535655897637547e-12 8.85267789671057e-12 4.636975222507721e-12 5295/3727/27161/3725/2354/2963/3838/5434/5440/6464/857/7764/5241/9687/5430/5436/5451/2625/57690/3315/27327/10274/5441/10735/192670/200845/5438/5431/5885/2100/5435/4313/5433/865/1105/1655/2289/2099/4609/2494/2962/8850/10524/1387/5437/3320/2033/8243/9126/595/8312/5439/192669/3065/861/23028/23112/10498/3326/7514/1025/2353/23030/1386/6908/1956/5536/3169/5296/4343/808/3845/904/3276/3265/26523/801/8202/5432/2288/10728/805/7528 83 Rotavirus_C R-HSA-449147 Signaling by Interleukins 141/1879 461/10654 2.6177260983202003e-12 1.3162221185128077e-11 6.8942860251679765e-12 5295/8454/7124/1147/5778/5718/54014/834/5689/3725/8945/1326/9655/5684/351/6464/5720/3667/4790/6627/6885/6597/5682/5783/5700/7412/122706/7184/5707/27250/5451/9021/7422/5690/2625/8878/5717/821/9491/6500/23198/3091/143471/5706/5705/9987/10197/8517/7534/3313/332/4313/7316/10213/5709/6175/9978/5695/79155/3185/7335/5970/4792/9261/4793/5714/8651/4609/6647/7867/9861/5566/5715/5519/5711/1432/5701/867/5688/79923/5687/6950/23291/3636/836/5685/5683/5698/5708/3320/5692/5686/200081/5713/4843/2335/595/5699/5710/3181/10454/5702/998/7157/5478/5719/4001/3654/5704/6233/2885/1398/5716/8660/2353/604/7311/1154/5518/1386/5896/5296/552900/8835/5600/7431/7334/5694/3312/3551/4170/5693/5721/5696/5691/4791/5034/51231/829/7314/5515 141 Rotavirus_C R-HSA-9006931 Signaling by Nuclear Receptors 102/1879 299/10654 2.714219396748299e-12 1.3592810738915481e-11 7.11982603862817e-12 5295/3727/5161/5105/27161/3725/2354/2963/3838/5434/5440/6464/8841/857/7764/79718/5241/9687/5160/5430/5436/5451/2625/57690/3315/27327/10274/1737/5915/5441/10735/192670/200845/5438/5431/5885/2100/5435/4313/5433/9611/865/1105/2874/1655/2194/9612/2289/2099/4609/2494/2962/8850/10524/1387/5437/6907/3320/2033/5162/221656/8243/9126/595/8312/5439/192669/3065/861/23028/6256/23112/10498/3326/7514/1025/2353/1738/23030/1386/6908/1956/5914/5536/3169/5296/4343/808/3845/904/3276/3265/26523/801/5916/29116/8202/5432/2288/10728/805/7528 102 Rotavirus_C R-HSA-8943724 Regulation of PTEN gene transcription 35/1879 61/10654 3.2384482924123656e-12 1.6153534908766062e-11 8.461116737986597e-12 1912/3725/8841/5468/23186/2146/5978/9112/9219/8535/51564/6045/80012/5931/1911/1108/10014/5928/84733/57459/54815/23512/57332/3066/3065/7157/1107/23028/57504/1386/8726/648/23466/53615/6015 35 Rotavirus_C R-HSA-141424 Amplification of signal from the kinetochores 46/1879 96/10654 7.716906066825616e-12 3.818800946903427e-11 2.0002631494205777e-11 55839/79682/5903/54908/55143/1783/1058/991/401541/79019/80152/9212/3619/79172/348995/23421/79023/57122/64105/6232/332/1780/1781/5501/4085/23279/55166/79902/54821/5519/2491/699/1060/91687/5529/51143/7514/9184/5518/5347/6396/64946/10726/55746/5515/1778 46 Rotavirus_C R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 46/1879 96/10654 7.716906066825616e-12 3.818800946903427e-11 2.0002631494205777e-11 55839/79682/5903/54908/55143/1783/1058/991/401541/79019/80152/9212/3619/79172/348995/23421/79023/57122/64105/6232/332/1780/1781/5501/4085/23279/55166/79902/54821/5519/2491/699/1060/91687/5529/51143/7514/9184/5518/5347/6396/64946/10726/55746/5515/1778 46 Rotavirus_C R-HSA-6784531 tRNA processing in the nucleus 33/1879 57/10654 9.627628253835374e-12 4.745586840079484e-11 2.485707584807061e-11 23165/5903/55706/7175/9631/10940/29894/348995/79023/57122/23636/10762/23511/53371/283742/23279/4927/9688/79042/79902/9883/23225/5901/8086/10556/1653/9972/8021/6396/129401/55746/51493/8480 33 Rotavirus_C R-HSA-5673001 RAF/MAP kinase cascade 88/1879 249/10654 1.0261735303481978e-11 5.038310823513505e-11 2.639034507355737e-11 5718/818/5689/57554/5684/6464/6711/5720/3667/71/5682/5700/122706/5707/3674/5690/5717/9491/23198/409/143471/5706/5705/10197/2260/8452/7316/10213/5709/9978/5695/84078/5714/9861/5715/5519/5711/2261/5701/5688/5687/5685/54756/5683/5698/5708/5692/5686/5713/2335/408/5699/5529/5710/5702/5719/9693/1742/5704/6233/2885/6709/5716/8660/7311/5518/1956/60/4254/5536/399473/808/3845/5694/3265/801/200734/4763/5693/5721/5696/5691/5245/7529/7314/161742/805/5515 88 Rotavirus_C R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 26/1879 39/10654 1.6517997533453102e-11 8.078333168704408e-11 4.2313784799923034e-11 10694/26224/8841/22803/8237/10575/10528/898/10517/7203/10576/908/26272/26270/6950/55294/26190/10238/7157/10574/6468/83752/54461/22948/26234/84261 26 Rotavirus_C R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 20/1879 25/10654 1.66792315108504e-11 8.125446634857859e-11 4.256056207765635e-11 10694/84617/10575/10382/7277/10381/7278/7203/10576/908/6950/7846/113457/347733/81027/10574/10383/84790/22948/7280 20 Rotavirus_C R-HSA-5684996 MAPK1/MAPK3 signaling 89/1879 255/10654 1.706222412484615e-11 8.279807986165652e-11 4.336909681672441e-11 5718/818/5689/57554/5684/6464/6711/5720/3667/71/5682/5700/122706/5707/3674/5690/5717/9491/23198/409/143471/5706/5705/10197/2260/8452/7316/10213/5709/9978/5695/983/84078/5714/9861/5715/5519/5711/2261/5701/5688/5687/5685/54756/5683/5698/5708/5692/5686/5713/2335/408/5699/5529/5710/5702/5719/9693/1742/5704/6233/2885/6709/5716/8660/7311/5518/1956/60/4254/5536/399473/808/3845/5694/3265/801/200734/4763/5693/5721/5696/5691/5245/7529/7314/161742/805/5515 89 Rotavirus_C R-HSA-176412 Phosphorylation of the APC/C 17/1879 19/10654 1.734349976701045e-11 8.383807609381114e-11 4.391384009285719e-11 11065/246184/7321/8697/8881/891/983/51433/51529/7324/64682/29945/10393/51434/5347/29882/996 17 Rotavirus_C R-HSA-167161 HIV Transcription Initiation 29/1879 47/10654 1.9469023307721156e-11 9.198195162742222e-11 4.81795492381739e-11 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/5433/4331/8148/2966/2962/5437/2965/2068/5439/2071/2968/6881/2967/51616/6908/1022/5432/6877 29 Rotavirus_C R-HSA-167162 RNA Polymerase II HIV Promoter Escape 29/1879 47/10654 1.9469023307721156e-11 9.198195162742222e-11 4.81795492381739e-11 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/5433/4331/8148/2966/2962/5437/2965/2068/5439/2071/2968/6881/2967/51616/6908/1022/5432/6877 29 Rotavirus_C R-HSA-73776 RNA Polymerase II Promoter Escape 29/1879 47/10654 1.9469023307721156e-11 9.198195162742222e-11 4.81795492381739e-11 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/5433/4331/8148/2966/2962/5437/2965/2068/5439/2071/2968/6881/2967/51616/6908/1022/5432/6877 29 Rotavirus_C R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 29/1879 47/10654 1.9469023307721156e-11 9.198195162742222e-11 4.81795492381739e-11 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/5433/4331/8148/2966/2962/5437/2965/2068/5439/2071/2968/6881/2967/51616/6908/1022/5432/6877 29 Rotavirus_C R-HSA-75953 RNA Polymerase II Transcription Initiation 29/1879 47/10654 1.9469023307721156e-11 9.198195162742222e-11 4.81795492381739e-11 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/5433/4331/8148/2966/2962/5437/2965/2068/5439/2071/2968/6881/2967/51616/6908/1022/5432/6877 29 Rotavirus_C R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 29/1879 47/10654 1.9469023307721156e-11 9.198195162742222e-11 4.81795492381739e-11 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/5433/4331/8148/2966/2962/5437/2965/2068/5439/2071/2968/6881/2967/51616/6908/1022/5432/6877 29 Rotavirus_C R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 23/1879 32/10654 2.2503864814237592e-11 1.0592044641889273e-10 5.5480442339810134e-11 10694/84617/5204/10575/10382/5203/7277/10381/7278/7203/10576/908/6950/7846/113457/347733/81027/10574/10383/60/84790/22948/7280 23 Rotavirus_C R-HSA-2559583 Cellular Senescence 73/1879 195/10654 2.8223453212227103e-11 1.3234368322737204e-10 6.93207622756455e-11 1912/7014/3725/25913/1019/11065/4790/246184/7290/7321/2146/10111/8535/6045/8697/57690/27327/80012/898/5931/5925/7013/472/79813/192670/8881/29855/7316/5970/9261/1911/26277/7867/51433/5928/1432/10524/84733/4683/65057/23512/57332/25842/192669/7157/51529/23135/7324/4001/64682/29945/10393/23112/6233/51434/2353/51343/7311/57634/4343/8726/29882/648/5600/23466/4217/26523/54386/10919/7314/996/6015/4193 73 Rotavirus_C R-HSA-9607240 FLT3 Signaling 91/1879 267/10654 4.44049955861737e-11 2.074442331115279e-10 1.0865794285226321e-10 5295/54106/5718/818/5689/57554/5684/6464/6711/5720/3667/71/5682/5700/122706/5707/3674/5690/5717/9491/23198/409/143471/5706/5705/10197/2260/8452/7316/10213/5709/9978/5695/84078/5714/9861/5715/5519/5711/2261/5701/5688/5687/5685/54756/5683/5698/5708/5692/5686/5713/2335/408/5699/5529/5710/5702/5719/9693/1742/5704/6233/2885/6709/5716/8660/7311/5518/1956/60/4254/5536/5296/399473/808/3845/5694/3265/801/200734/4763/5693/5721/5696/5691/5245/7529/7314/161742/805/5515 91 Rotavirus_C R-HSA-5250941 Negative epigenetic regulation of rRNA expression 49/1879 110/10654 4.491627117810917e-11 2.090526822118687e-10 1.0950043805111333e-10 8467/5434/5440/902/9015/51742/79595/79101/1786/6839/9014/29115/30834/25885/404672/221830/5441/51082/8932/5435/8819/7270/4331/9013/23309/7343/2966/64426/79685/5437/1789/11176/2965/64425/2068/3066/3065/2071/10849/2968/84172/2967/6908/23411/25942/23378/10284/1022/9533 49 Rotavirus_C R-HSA-5696394 DNA Damage Recognition in GG-NER 25/1879 38/10654 6.332623531654543e-11 2.93646098578944e-10 1.5380992047644367e-10 9318/83444/86/8450/7316/9978/64708/1643/10980/79913/1642/54617/10920/10987/6233/2873/7311/60/8533/8607/50813/7314/51138/8451/7528 25 Rotavirus_C R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 17/1879 20/10654 9.652827508436214e-11 4.4431397207949044e-10 2.3272877468095052e-10 11065/246184/7321/991/8697/8881/4085/51433/51529/7324/64682/29945/10393/51434/9184/29882/996 17 Rotavirus_C R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 17/1879 20/10654 9.652827508436214e-11 4.4431397207949044e-10 2.3272877468095052e-10 11065/246184/7321/991/8697/8881/4085/51433/51529/7324/64682/29945/10393/51434/9184/29882/996 17 Rotavirus_C R-HSA-170834 Signaling by TGF-beta Receptor Complex 37/1879 73/10654 1.0999276095496786e-10 5.044356656249807e-10 2.642201275301522e-10 57154/7321/6497/10273/4738/51592/64750/7323/8239/54778/7316/9611/5501/9612/4609/22938/23327/867/23645/8812/905/5494/3065/9958/9040/5499/6233/7514/1025/7311/56288/25937/387/904/5500/7314/4221 37 Rotavirus_C R-HSA-73854 RNA Polymerase I Promoter Clearance 48/1879 110/10654 1.710968780631189e-10 7.818003333395069e-10 4.0950194019716893e-10 5434/5440/902/9015/2648/79101/2074/9112/9219/9014/30834/25885/404672/5931/221830/5441/51082/11335/8932/5435/7270/4331/9013/7343/1108/2966/8850/5928/5437/57459/2965/54815/64425/2068/3066/3065/2071/1107/10849/2968/57504/84172/2967/6908/53615/1022/10919/9533 48 Rotavirus_C R-HSA-70171 Glycolysis 36/1879 71/10654 1.9373351892755504e-10 8.820158752629051e-10 4.619941905908777e-10 23165/5903/2597/55706/7175/9631/5315/348995/79023/57122/23636/5214/10762/23511/53371/23279/4927/9688/79902/5566/5519/9883/2023/226/23225/8086/5213/9972/5518/8021/6396/129401/2026/55746/8480/5515 36 Rotavirus_C R-HSA-5389840 Mitochondrial translation elongation 41/1879 87/10654 2.0344205241290105e-10 9.228603247135946e-10 4.833882481054057e-10 6182/51253/65993/56945/54534/26284/60488/79590/7818/64949/65003/6150/28998/10573/219927/64963/64960/10240/64969/51081/54148/51069/23107/65008/78988/28973/740/90480/55168/28957/9801/64928/51649/54998/64965/51073/92259/7284/54460/65080/55037 41 Rotavirus_C R-HSA-73864 RNA Polymerase I Transcription 48/1879 112/10654 3.643949201198785e-10 1.6470124187367795e-9 8.62694414724242e-10 5434/5440/902/9015/2648/79101/2074/9112/9219/9014/30834/25885/404672/5931/221830/5441/51082/11335/8932/5435/7270/4331/9013/7343/1108/2966/8850/5928/5437/57459/2965/54815/64425/2068/3066/3065/2071/1107/10849/2968/57504/84172/2967/6908/53615/1022/10919/9533 48 Rotavirus_C R-HSA-5696395 Formation of Incision Complex in GG-NER 26/1879 43/10654 4.116619028018557e-10 1.8539593608198683e-9 9.710918797635596e-10 6118/902/404672/9557/7336/8450/54778/7316/9978/4331/1643/2966/6119/1642/2965/2068/2071/7329/6233/2968/7311/2967/7334/1022/7314/8451 26 Rotavirus_C R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 16/1879 19/10654 4.693725311679924e-10 2.0987657465083086e-9 1.0993198756302978e-9 11065/246184/7321/991/8697/8881/51433/51529/7324/64682/29945/10393/51434/51343/29882/996 16 Rotavirus_C R-HSA-8851708 Signaling by FGFR2 IIIa TM 16/1879 19/10654 4.693725311679924e-10 2.0987657465083086e-9 1.0993198756302978e-9 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/5439/5432/22916 16 Rotavirus_C R-HSA-5654738 Signaling by FGFR2 36/1879 73/10654 5.287405295504639e-10 2.3558118967871206e-9 1.2339589807452295e-9 5295/2963/5434/5440/6464/23543/5430/5436/3178/5441/5438/5431/5435/4686/7316/5433/3185/2962/867/5437/4670/5439/7072/6233/2885/3187/7073/7311/5518/3845/3265/5432/22916/5725/7314/5515 36 Rotavirus_C R-HSA-350054 Notch-HLH transcription pathway 20/1879 28/10654 5.657996439852232e-10 2.5119899087570903e-9 1.3157640097155434e-9 8841/79718/79885/2648/9734/55869/51564/10013/83933/9611/9759/9612/10014/22938/8850/1387/6907/3066/3065/4851 20 Rotavirus_C R-HSA-427413 NoRC negatively regulates rRNA expression 46/1879 107/10654 7.47671870449196e-10 3.3077214904678216e-9 1.7325630473864575e-9 8467/5434/5440/902/9015/51742/79595/79101/1786/9014/29115/30834/25885/404672/221830/5441/51082/8932/5435/8819/7270/4331/9013/23309/7343/2966/64426/79685/5437/1789/11176/2965/64425/2068/3066/3065/2071/10849/2968/84172/2967/6908/25942/10284/1022/9533 46 Rotavirus_C R-HSA-190236 Signaling by FGFR 40/1879 87/10654 8.540899244920137e-10 3.738883165958046e-9 1.9584027344811353e-9 5295/2963/5434/5440/6464/23543/5430/5436/3178/5441/2260/5438/5431/5435/4686/7316/5433/3185/2962/2261/867/5437/4670/5439/7072/6233/2885/3187/7073/7311/5518/3845/3265/200734/5432/22916/5725/7314/161742/5515 40 Rotavirus_C R-HSA-5368286 Mitochondrial translation initiation 40/1879 87/10654 8.540899244920137e-10 3.738883165958046e-9 1.9584027344811353e-9 6182/51253/65993/56945/54534/26284/60488/79590/7818/64949/65003/6150/28998/10573/219927/64963/64960/10240/64969/51081/54148/51069/23107/65008/78988/28973/740/90480/55168/28957/9801/64928/51649/54998/64965/51073/92259/54460/65080/55037 40 Rotavirus_C R-HSA-5419276 Mitochondrial translation termination 40/1879 87/10654 8.540899244920137e-10 3.738883165958046e-9 1.9584027344811353e-9 6182/51253/65993/56945/54534/26284/60488/79590/7818/64949/65003/6150/28998/10573/219927/64963/64960/10240/64969/51081/54148/51069/23107/65008/78988/28973/740/90480/55168/28957/9801/64928/51649/54998/64965/51073/92259/54460/65080/55037 40 Rotavirus_C R-HSA-211000 Gene Silencing by RNA 54/1879 136/10654 9.057883676761608e-10 3.951383401848617e-9 2.069708978772229e-9 23165/27161/6895/5434/5440/8468/5903/55706/7175/9631/5430/5436/57690/27327/348995/79023/57122/5441/23636/192670/5438/10762/5431/23511/5435/54487/5433/53371/23279/4927/9688/79902/9883/5437/23225/3320/54514/5439/192669/5901/8086/23112/29102/9972/8021/6396/129401/144233/26523/5432/55746/23405/8480/10526 54 Rotavirus_C R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 40/1879 88/10654 1.3019349946401608e-9 5.659800740588477e-9 2.9645668920351615e-9 8454/8945/22981/7531/11190/203068/7532/84962/1454/10382/6500/121441/7277/1781/7316/891/983/1639/6790/10121/9702/5566/23291/7846/7283/3320/11064/10540/10733/79866/4751/6233/7311/5518/10383/5347/1453/5500/7314/1778 40 Rotavirus_C R-HSA-3371568 Attenuation phase 13/1879 14/10654 1.8089866713963148e-9 7.782994201333973e-9 4.076681845830726e-9 3303/3337/3305/1387/3320/2033/3326/3306/3304/3312/3297/2288/10728 13 Rotavirus_C R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 13/1879 14/10654 1.8089866713963148e-9 7.782994201333973e-9 4.076681845830726e-9 8841/79718/9611/2874/9612/5566/6907/3065/4204/25942/808/801/805 13 Rotavirus_C R-HSA-9005895 Pervasive developmental disorders 13/1879 14/10654 1.8089866713963148e-9 7.782994201333973e-9 4.076681845830726e-9 8841/79718/9611/2874/9612/5566/6907/3065/4204/25942/808/801/805 13 Rotavirus_C R-HSA-5250913 Positive epigenetic regulation of rRNA expression 45/1879 106/10654 1.8635854012096565e-9 7.99044151477565e-9 4.185341402139927e-9 8467/23451/5434/5440/9015/10514/2648/79101/2074/9112/9219/9014/30834/25885/5931/221830/5441/51082/11335/5435/9031/7270/9013/1108/8850/5928/2932/5437/7913/57459/54815/2033/64425/3066/3065/1107/10849/57504/84172/6908/60/53615/10919/9533/9188 45 Rotavirus_C R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 14/1879 16/10654 2.272503492995485e-9 9.710492741400503e-9 5.0862930703653215e-9 8454/1147/8945/1326/4790/6500/8517/7316/79155/23291/6233/7311/3551/7314 14 Rotavirus_C R-HSA-5626467 RHO GTPases activate IQGAPs 21/1879 32/10654 2.3721279868094594e-9 1.0101715100290624e-8 5.291212802657691e-9 84617/71/1495/1499/10382/7277/10381/7278/7846/113457/347733/998/81027/10383/60/84790/808/801/7280/4221/805 21 Rotavirus_C R-HSA-5368287 Mitochondrial translation 41/1879 93/10654 2.5156676938387327e-9 1.0676664246393535e-8 5.592367433582625e-9 6182/51253/65993/56945/54534/26284/60488/79590/7818/64949/65003/6150/28998/10573/219927/64963/64960/10240/64969/51081/54148/51069/23107/65008/78988/28973/740/90480/55168/28957/9801/64928/51649/54998/64965/51073/92259/7284/54460/65080/55037 41 Rotavirus_C R-HSA-400253 Circadian Clock 34/1879 70/10654 2.6532109039609296e-9 1.1222365039726634e-8 5.878201967168062e-9 8454/5187/26224/8945/8841/79718/5936/10135/1454/1407/6500/3091/1408/7316/9611/5501/8553/1387/2908/6907/2033/79365/6256/5499/10498/6233/7311/23054/8864/1386/23411/1453/5500/7314 34 Rotavirus_C R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 23/1879 38/10654 4.1545074881555206e-9 1.7513277357477145e-8 9.173341006985254e-9 1912/6597/8535/6045/80012/6598/6599/86/865/1911/6603/84733/8289/10138/2033/6605/57332/861/648/6601/23466/55193/6015 23 Rotavirus_C R-HSA-5633007 Regulation of TP53 Activity 59/1879 160/10654 4.37773628878452e-9 1.8392368568987313e-8 9.633803277685469e-9 6118/9891/64769/10111/9219/8445/9212/5982/5931/6749/545/472/79813/580/7316/80196/983/6790/641/1108/8148/5519/6119/5928/1432/10524/4683/57459/1616/9099/5985/54815/2033/1111/3066/3065/7157/1107/91875/6233/672/5932/7311/6881/51616/5518/6908/10419/11198/5600/7874/1020/53615/83695/10919/6877/7314/4193/5515 59 Rotavirus_C R-HSA-5696400 Dual Incision in GG-NER 24/1879 41/10654 4.9109244170725e-9 2.056346946546746e-8 1.07710118353676e-8 6118/5982/404672/9557/8450/7316/9978/5111/5426/1643/2966/6119/1642/2965/5985/2068/2071/6233/2968/7311/2967/5424/7314/8451 24 Rotavirus_C R-HSA-390466 Chaperonin-mediated protein folding 41/1879 95/10654 5.426602285565807e-9 2.2647020205094633e-8 1.1862362189149114e-8 10694/26224/84617/8841/22803/5204/8237/10575/10382/10528/5203/898/7277/10381/7278/10517/7203/10576/908/26272/26270/6950/7846/113457/347733/55294/26190/10238/7157/81027/10574/6468/83752/10383/60/54461/84790/22948/26234/7280/84261 41 Rotavirus_C R-HSA-4655427 SUMOylation of DNA methylation proteins 14/1879 17/10654 1.0774155451566363e-8 4.4814759552694637e-008 2.3473680175995258e-8 1912/1788/8535/1786/6045/80012/1911/84733/1789/57332/7329/648/7703/6015 14 Rotavirus_C R-HSA-391251 Protein folding 42/1879 101/10654 1.3459310224196177e-8 5.579820000229674e-8 2.922673499363617e-8 10694/26224/84617/8841/22803/5204/8237/10575/10382/10528/5203/898/7277/10381/7278/10517/7203/10576/908/26272/26270/6950/7846/113457/347733/55294/26190/10238/7157/81027/10574/6468/83752/10383/60/54461/84790/22948/26234/7280/84261/6904 42 Rotavirus_C R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 40/1879 94/10654 1.3568251702233899e-8 5.606419515246482e-8 2.9366061526808124e-8 8454/1147/3725/8945/1326/351/4790/6885/7321/6500/841/8517/7323/7316/79155/7335/5970/4792/9261/4793/7867/7322/5519/1432/23291/10454/3654/6233/2353/7311/5518/1386/8772/5600/7334/3551/4791/51231/7314/5515 40 Rotavirus_C R-HSA-8953750 Transcriptional Regulation by E2F6 21/1879 35/10654 2.4736788245744107e-8 1.018765094857619e-7 5.336225442208649e-8 23468/80314/2146/6045/80012/5931/79813/4149/11335/1911/5928/10138/23512/1111/672/5932/8726/648/7703/10919/6015 21 Rotavirus_C R-HSA-8986944 Transcriptional Regulation by MECP2 30/1879 62/10654 2.549976106563407e-8 1.046744290300782e-7 5.482778651903373e-8 818/27161/8841/2290/79718/5468/9212/57690/27327/192670/54487/9611/2874/9612/2289/5566/6907/5728/192669/3066/3065/4204/3654/23112/25942/4343/808/26523/801/805 30 Rotavirus_C R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 24/1879 44/10654 3.301416804833483e-8 1.3507757645920002e-7 7.075275780568489e-8 7321/6497/51592/64750/7323/8239/54778/7316/9611/9612/4609/22938/23327/8812/905/5494/3065/6233/1025/7311/25937/904/7314/4221 24 Rotavirus_C R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 30/1879 63/10654 4.052639341409712e-8 1.6527376076367946e-7 8.656932315097721e-8 1147/170506/5434/5440/6737/4790/1499/7520/5441/51082/8517/5591/5435/7316/51428/5970/4792/4793/3428/1387/5437/2033/22954/1660/6233/7311/3551/4791/7314/9533 30 Rotavirus_C R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 39/1879 94/10654 4.755078839789166e-8 1.9329086712389726e-7 1.0124450161273582e-7 84617/22981/7531/11190/203068/7532/1454/10382/121441/7277/10381/7278/1781/983/1639/10121/9702/5566/7846/113457/7283/347733/3320/80097/10426/11064/10540/81027/10733/85378/4751/5518/10383/5347/84790/1453/27229/7280/1778 39 Rotavirus_C R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 16/1879 23/10654 5.790413348744727e-8 2.338940312479663e-7 1.2251217543928283e-7 7321/6497/51592/64750/7323/8239/54778/7316/9611/9612/23327/5494/3065/6233/7311/7314 16 Rotavirus_C R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 23/1879 42/10654 5.7913058855327116e-8 2.338940312479663e-7 1.2251217543928283e-7 9070/51176/8945/1499/8085/5929/283149/7534/7316/83439/6934/607/324/3065/57680/6233/6932/7514/90780/7311/26108/7314/4221 23 Rotavirus_C R-HSA-73893 DNA Damage Bypass 25/1879 48/10654 5.8245782494128834e-8 2.344814137705765e-7 1.2281984259212137e-7 6118/56852/7320/5982/7706/8450/7316/9978/5111/5426/9100/10459/7415/6119/1642/5985/25898/9246/57599/6233/7311/7318/5424/7314/8451 25 Rotavirus_C R-HSA-450294 MAP kinase activation 30/1879 64/10654 6.350888592823696e-8 2.548497601992073e-7 1.334886502472727e-7 8454/1147/3725/8945/1326/4790/6885/6500/8517/7316/79155/7335/9261/7867/5519/1432/23291/10454/3654/6233/2353/7311/5518/1386/5600/7334/3551/51231/7314/5515 30 Rotavirus_C R-HSA-913531 Interferon Signaling 66/1879 199/10654 6.960612442848683e-8 2.784244977139473e-7 1.4583694474170942e-7 3839/23165/818/201626/3837/3838/5903/6737/55706/7175/9631/7412/2316/9021/9830/3841/23650/348995/79023/57122/23636/8638/25820/7706/10762/9470/23511/7316/53371/103/4734/8651/23279/4927/9688/79902/3840/25939/9883/6059/23225/1981/1973/10612/3454/8086/7324/3836/9246/51191/6233/7311/9972/7318/5610/8021/9775/6396/129401/7334/4261/55746/5696/5495/8480/7314 66 Rotavirus_C R-HSA-5578749 Transcriptional regulation by small RNAs 42/1879 106/10654 7.111905617229637e-8 2.835702494513218e-7 1.485322561023823e-7 23165/27161/5434/5440/5903/55706/7175/9631/5430/5436/27327/348995/79023/57122/5441/23636/5438/10762/5431/23511/5435/5433/53371/23279/4927/9688/79902/9883/5437/23225/5439/5901/8086/9972/8021/6396/129401/26523/5432/55746/8480/10526 42 Rotavirus_C R-HSA-166166 MyD88-independent TLR4 cascade 40/1879 99/10654 7.711376520736107e-8 3.05526689998785e-7 1.6003289714918702e-7 8454/1147/3725/8945/1326/351/4790/6885/7321/6500/841/8517/7323/7316/79155/7335/5970/4792/9261/4793/7867/7322/5519/1432/23291/10454/3654/6233/2353/7311/5518/1386/8772/5600/7334/3551/4791/51231/7314/5515 40 Rotavirus_C R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 40/1879 99/10654 7.711376520736107e-8 3.05526689998785e-7 1.6003289714918702e-7 8454/1147/3725/8945/1326/351/4790/6885/7321/6500/841/8517/7323/7316/79155/7335/5970/4792/9261/4793/7867/7322/5519/1432/23291/10454/3654/6233/2353/7311/5518/1386/8772/5600/7334/3551/4791/51231/7314/5515 40 Rotavirus_C R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 36/1879 85/10654 8.274217567298892e-8 3.247435860269032e-7 1.7009858255823162e-7 8454/1147/3725/8945/1326/351/4790/6885/4214/6500/8517/7316/79155/7335/5970/4792/9261/4793/7867/5519/1432/23291/10454/3654/6233/2353/7311/5518/1386/5600/7334/3551/4791/51231/7314/5515 36 Rotavirus_C R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 36/1879 85/10654 8.274217567298892e-8 3.247435860269032e-7 1.7009858255823162e-7 8454/1147/3725/8945/1326/351/4790/6885/4214/6500/8517/7316/79155/7335/5970/4792/9261/4793/7867/5519/1432/23291/10454/3654/6233/2353/7311/5518/1386/5600/7334/3551/4791/51231/7314/5515 36 Rotavirus_C R-HSA-975871 MyD88 cascade initiated on plasma membrane 36/1879 85/10654 8.274217567298892e-8 3.247435860269032e-7 1.7009858255823162e-7 8454/1147/3725/8945/1326/351/4790/6885/4214/6500/8517/7316/79155/7335/5970/4792/9261/4793/7867/5519/1432/23291/10454/3654/6233/2353/7311/5518/1386/5600/7334/3551/4791/51231/7314/5515 36 Rotavirus_C R-HSA-72306 tRNA processing 42/1879 107/10654 9.735662573234107e-8 3.8090779817778443e-7 1.9951703233963317e-7 23165/5903/63892/55706/7175/9631/3028/51605/10940/29894/348995/79023/57122/23636/10762/23511/53371/54931/283742/23279/4927/9688/55644/79042/79902/9883/23225/5901/8086/10556/80324/1653/9972/24140/8021/8270/6396/129401/55746/51493/8480/54888 42 Rotavirus_C R-HSA-70326 Glucose metabolism 37/1879 91/10654 1.945700992863831e-7 7.588840009549896e-7 3.974985140364541e-7 5105/23165/5903/2597/55706/7175/9631/5315/348995/79023/57122/23636/5214/10762/23511/53371/23279/4927/9688/79902/5566/5519/9883/2023/226/23225/8086/5213/9972/5518/8021/6396/129401/2026/55746/8480/5515 37 Rotavirus_C R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 38/1879 95/10654 2.2135110884211505e-7 8.579925333446688e-7 4.4941092002163163e-7 8454/1147/3725/8945/1326/351/4790/6885/4214/6500/8517/7316/79155/7335/5970/4792/9261/4793/8651/7867/5519/1432/23291/10454/3654/6233/2353/7311/5518/1386/5600/7334/7097/3551/4791/51231/7314/5515 38 Rotavirus_C R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 38/1879 95/10654 2.2135110884211505e-7 8.579925333446688e-7 4.4941092002163163e-7 8454/1147/3725/8945/1326/351/4790/6885/4214/6500/8517/7316/79155/7335/5970/4792/9261/4793/8651/7867/5519/1432/23291/10454/3654/6233/2353/7311/5518/1386/5600/7334/7097/3551/4791/51231/7314/5515 38 Rotavirus_C R-HSA-73856 RNA Polymerase II Transcription Termination 30/1879 67/10654 2.2599887384002902e-7 8.733042902707294e-7 4.574311189159781e-7 10921/53981/6635/8683/6430/11051/6428/8106/29894/6637/4686/9785/11338/4116/1477/7307/6429/51213/10250/10189/9295/23283/6636/6634/9775/6427/6426/22916/1479/6628 30 Rotavirus_C R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 18/1879 30/10654 2.520682283522934e-7 9.710443750679117e-7 5.086267409343443e-7 6118/56852/7320/5982/8450/7316/9978/5111/5426/6119/1642/5985/57599/6233/7311/5424/7314/8451 18 Rotavirus_C R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 37/1879 92/10654 2.7078061213427245e-7 1.0399304490555495e-6 5.447088193724628e-7 54106/8454/1147/3725/8945/1326/351/4790/6885/4214/6500/8517/7316/79155/7335/5970/4792/9261/4793/7867/5519/1432/23291/10454/3654/6233/2353/7311/5518/1386/5600/7334/3551/4791/51231/7314/5515 37 Rotavirus_C R-HSA-3899300 SUMOylation of transcription cofactors 23/1879 45/10654 3.09278079373782e-7 1.1841472641467126e-6 6.202486510538103e-7 1912/8535/6045/4869/80012/1655/9612/1911/1387/84733/10521/1616/2033/57332/7329/115426/10155/25942/6294/648/7703/11315/6015 23 Rotavirus_C R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 37/1879 93/10654 3.74148348607157e-7 1.4238107369488165e-6 7.457828225316233e-7 54106/8454/1147/3725/8945/1326/351/4790/6885/4214/6500/8517/7316/79155/7335/5970/4792/9261/4793/7867/5519/1432/23291/10454/3654/6233/2353/7311/5518/1386/5600/7334/3551/4791/51231/7314/5515 37 Rotavirus_C R-HSA-975155 MyD88 dependent cascade initiated on endosome 37/1879 93/10654 3.74148348607157e-7 1.4238107369488165e-6 7.457828225316233e-7 54106/8454/1147/3725/8945/1326/351/4790/6885/4214/6500/8517/7316/79155/7335/5970/4792/9261/4793/7867/5519/1432/23291/10454/3654/6233/2353/7311/5518/1386/5600/7334/3551/4791/51231/7314/5515 37 Rotavirus_C R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 26/1879 55/10654 3.884405187142697e-7 1.4737197861523202e-6 7.719248585613717e-7 1147/834/351/4790/6885/841/8517/7316/7335/5970/22861/7128/1432/10628/10454/83737/3654/6233/3326/7311/5600/7334/1540/3551/4791/7314 26 Rotavirus_C R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 38/1879 98/10654 5.665169981240111e-7 2.1363833784676563e-6 1.1190237470870607e-6 8454/1147/3725/8945/1326/351/4790/6885/4214/6500/8517/7316/79155/7335/5970/4792/9261/4793/8651/7867/5519/1432/23291/10454/3654/6233/2353/7311/5518/1386/5600/7334/7097/3551/4791/51231/7314/5515 38 Rotavirus_C R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 38/1879 98/10654 5.665169981240111e-7 2.1363833784676563e-6 1.1190237470870607e-6 8454/1147/3725/8945/1326/351/4790/6885/4214/6500/8517/7316/79155/7335/5970/4792/9261/4793/8651/7867/5519/1432/23291/10454/3654/6233/2353/7311/5518/1386/5600/7334/7097/3551/4791/51231/7314/5515 38 Rotavirus_C R-HSA-195258 RHO GTPase Effectors 93/1879 327/10654 6.598964830067512e-7 2.4810522424157734e-6 1.299559060892069e-6 55839/84617/79682/5903/54908/71/55143/1495/1499/7531/1783/1058/991/1856/401541/79019/2316/7532/10971/80152/10382/9212/3619/79172/1080/7533/7277/348995/23421/79023/10381/57122/64105/7278/6232/7534/332/1780/1781/5501/4085/5585/5216/23279/55166/79902/54821/5519/1432/2017/2491/699/7846/113457/347733/752/1060/91687/5529/51143/998/81027/23028/354/1742/1855/2885/10097/1857/3817/7514/9184/367/5518/10383/5347/387/60/84790/808/6396/5600/801/64946/10726/55746/7280/5500/7529/4221/805/5515/1778 93 Rotavirus_C R-HSA-73887 Death Receptor Signalling 49/1879 141/10654 7.103589957892894e-7 2.6627828225394917e-6 1.394748359208091e-6 7124/1147/8841/7186/4790/6885/10018/7531/55072/9530/8878/7074/11214/23421/23385/841/27005/8517/9500/7316/5970/4792/8797/7128/9099/836/23365/10616/396/10454/3066/3065/57449/3654/83464/6233/7311/26574/387/8772/55851/51107/1540/3551/8743/8795/5663/7314/84894 49 Rotavirus_C R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 37/1879 97/10654 1.2744233629815268e-6 4.762919553590661e-6 2.4947863476433346e-6 54106/8454/1147/3725/8945/1326/351/4790/6885/4214/6500/8517/7316/79155/7335/5970/4792/9261/4793/7867/5519/1432/23291/10454/3654/6233/2353/7311/5518/1386/5600/7334/3551/4791/51231/7314/5515 37 Rotavirus_C R-HSA-3371511 HSF1 activation 10/1879 12/10654 1.330966083928227e-6 4.959433146065893e-6 2.5977188918774602e-6 6118/7531/1915/10013/7415/6119/3320/3326/3297/10728 10 Rotavirus_C R-HSA-390450 Folding of actin by CCT/TriC 9/1879 10/10654 1.368108878430734e-6 5.082707168531984e-6 2.6622890247144997e-6 10694/10575/7203/10576/908/6950/10574/60/22948 9 Rotavirus_C R-HSA-1221632 Meiotic synapsis 32/1879 79/10654 1.4208890775457517e-6 5.263174926293731e-6 2.756816864873881e-6 4000/7014/10388/25913/8468/25777/23224/27127/93426/10274/7013/545/10735/56158/5885/644186/26277/9985/23345/256126/10734/65057/8243/9126/7329/4001/50511/6847/672/3306/23353/54386 32 Rotavirus_C R-HSA-448424 Interleukin-17 signaling 30/1879 72/10654 1.4888198401126963e-6 5.498532270858689e-6 2.8800955143307242e-6 8454/1147/3725/8945/1326/4790/6885/6500/8517/7316/79155/7335/9261/7867/5519/1432/23291/10454/3654/6233/2353/7311/5518/1386/5600/7334/3551/51231/7314/5515 30 Rotavirus_C R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 17/1879 30/10654 1.6785245021434027e-6 6.18091963730453e-6 3.2375255877255105e-6 7124/1147/7186/6885/55072/27005/8517/7316/7128/9099/10616/10454/6233/7311/1540/3551/7314 17 Rotavirus_C R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 18/1879 33/10654 1.762104165997446e-6 6.469661043486224e-6 3.3887664621590026e-6 1147/351/4790/6885/8517/7316/7335/5970/4792/4793/10454/3654/6233/7311/7334/3551/4791/7314 18 Rotavirus_C R-HSA-168638 NOD1/2 Signaling Pathway 19/1879 36/10654 1.7678681830355978e-6 6.4718449273700836e-6 3.3899103663625035e-6 1147/834/6885/841/8517/7316/7335/7128/1432/10454/83737/3654/6233/7311/5600/7334/1540/3551/7314 19 Rotavirus_C R-HSA-73886 Chromosome Maintenance 40/1879 110/10654 2.0047628351098456e-6 7.3176765876312735e-6 3.832951499995193e-6 8467/7014/6118/55839/25913/79682/55320/1058/401541/79019/80152/4869/5982/79172/5931/7013/23421/55355/64105/10856/26277/54069/5111/5426/55166/6119/5928/1736/2491/5985/65057/1060/91687/387103/51773/8607/11339/64946/54386/5424 40 Rotavirus_C R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 26/1879 59/10654 2.084324009959772e-6 7.5859699432256816e-6 3.973481818252564e-6 7319/7321/79139/56852/9646/7320/79577/7336/5591/7323/7316/56254/5111/7415/7322/54623/118424/7324/6233/23168/7311/7334/6596/80349/7314/123169 26 Rotavirus_C R-HSA-1500620 Meiosis 42/1879 118/10654 2.1430288344396506e-6 7.777020581792588e-6 4.073552902687726e-6 4000/7014/6118/10388/25913/8468/1019/25777/10111/23224/27127/93426/10274/7013/545/472/23626/10735/56158/5885/644186/26277/641/9985/6119/23345/4683/256126/10734/65057/8243/9126/7329/4001/50511/6847/672/3306/5932/23353/56979/54386 42 Rotavirus_C R-HSA-8934593 Regulation of RUNX1 Expression and Activity 12/1879 17/10654 2.2553393939239947e-6 8.160939078592027e-6 4.274646919423939e-6 27161/894/57690/27327/192670/865/595/192669/861/23112/4343/26523 12 Rotavirus_C R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 35/1879 92/10654 2.6322145075016457e-6 9.497211998248013e-6 4.974578001436449e-6 6118/9891/10111/8445/9212/5982/6749/545/472/580/7316/6790/641/8148/6119/1432/10524/4683/5985/1111/7157/6233/672/5932/7311/6881/51616/6908/11198/5600/1020/83695/6877/7314/4193 35 Rotavirus_C R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 31/1879 78/10654 3.336567051306913e-6 1.2003971115621423e-5 6.287602156576549e-6 1147/351/7186/4790/7321/4214/841/7706/8517/7323/7316/5970/4792/4793/3093/7322/7128/1387/2033/83737/9246/51191/6233/7311/7318/5094/8772/1540/3551/4791/7314 31 Rotavirus_C R-HSA-209560 NF-kB is activated and signals survival 10/1879 13/10654 4.849653687818145e-6 1.7347904048995192e-5 9.086719541385576e-6 4790/8878/7316/5970/4792/3654/6233/7311/3551/7314 10 Rotavirus_C R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 10/1879 13/10654 4.849653687818145e-6 1.7347904048995192e-5 9.086719541385576e-6 7531/7532/10971/7533/7534/891/983/1111/7465/7529 10 Rotavirus_C R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 23/1879 51/10654 4.9772085584489794e-6 1.7753461866604337e-5 9.299148093908275e-6 84617/1783/10382/7277/10381/23299/7278/1780/1781/1639/10121/7846/113457/347733/51143/10540/81027/10383/84790/7280/829/22931/1778 23 Rotavirus_C R-HSA-9006936 Signaling by TGF-beta family members 37/1879 102/10654 5.130600257752961e-6 1.824861228041678e-5 9.558504666806502e-6 57154/7321/6497/10273/4738/51592/64750/7323/8239/54778/7316/9611/5501/9612/4609/22938/23327/867/23645/8812/905/5494/3065/9958/9040/5499/6233/7514/1025/7311/56288/25937/387/904/5500/7314/4221 37 Rotavirus_C R-HSA-72187 mRNA 3'-end processing 25/1879 58/10654 5.317239954788092e-6 1.8858879386387227e-5 9.878158615872912e-6 10921/53981/8683/6430/11051/6428/8106/29894/4686/9785/11338/4116/1477/7307/6429/51213/10250/10189/9295/23283/9775/6427/6426/22916/1479 25 Rotavirus_C R-HSA-2173789 TGF-beta receptor signaling activates SMADs 17/1879 32/10654 5.5419173510571605e-6 1.959456660111084e-5 1.0263506803843998e-5 57154/10273/4738/64750/7316/5501/23327/867/23645/9958/9040/5499/6233/7514/7311/5500/7314 17 Rotavirus_C R-HSA-68875 Mitotic Prophase 47/1879 142/10654 5.555967366928392e-6 1.959456660111084e-5 1.0263506803843998e-5 4000/23165/5903/55706/7175/9631/5925/348995/79023/57122/23636/23310/7443/10762/10051/23511/891/53371/26003/983/23279/4927/9688/79902/5519/9883/23225/8815/9663/8086/2010/4001/79648/23175/9972/5518/5347/54892/8021/6396/129401/55746/7112/10592/29781/8480/5515 47 Rotavirus_C R-HSA-190840 Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane 12/1879 18/10654 5.6764554426475556e-6 1.9963264646614436e-5 1.045662844698234e-5 84617/10382/7277/10381/7278/7846/113457/347733/81027/10383/84790/7280 12 Rotavirus_C R-HSA-69473 G2/M DNA damage checkpoint 35/1879 95/10654 6.142208010276385e-6 2.1540740697103736e-5 1.1282900163356001e-5 6118/7531/10111/7532/10971/51720/5982/7533/545/472/7336/7534/580/29086/891/983/641/9656/6119/10524/4683/5985/165918/1111/7157/8924/672/5932/7158/9025/79184/7334/7465/83695/7529 35 Rotavirus_C R-HSA-3371571 HSF1-dependent transactivation 14/1879 24/10654 8.960306346299033e-6 3.124875639433535e-5 1.6367895774063325e-5 818/3303/3337/3305/1387/3320/2033/3326/3306/3304/3312/3297/2288/10728 14 Rotavirus_C R-HSA-450302 activated TAK1 mediates p38 MAPK activation 14/1879 24/10654 8.960306346299033e-6 3.124875639433535e-5 1.6367895774063325e-5 6885/8517/7316/7335/9261/7867/1432/10454/3654/6233/7311/5600/7334/7314 14 Rotavirus_C R-HSA-205043 NRIF signals cell death from the nucleus 11/1879 16/10654 9.1309682030195e-6 3.1755478306056705e-5 1.6633313422459496e-5 8878/23421/23385/7316/83464/6233/7311/55851/51107/5663/7314 11 Rotavirus_C R-HSA-6807505 RNA polymerase II transcribes snRNA genes 29/1879 74/10654 9.498754705290712e-6 3.294304955962319e-5 1.7255355536947407e-5 2963/5434/5440/5430/5436/5451/5441/5438/5431/5435/4686/5433/2962/51808/5437/8812/905/5439/6827/1025/6908/51593/904/6829/1022/5432/22916/8178/6877 29 Rotavirus_C R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 31/1879 82/10654 1.1241991753933552e-5 3.868958629276219e-5 2.026535417890604e-5 22981/7531/11190/203068/7532/1454/10382/121441/7277/1781/983/1639/10121/9702/5566/7846/7283/3320/80097/10426/11064/10540/10733/85378/4751/5518/10383/5347/1453/27229/1778 31 Rotavirus_C R-HSA-380287 Centrosome maturation 31/1879 82/10654 1.1241991753933552e-5 3.868958629276219e-5 2.026535417890604e-5 22981/7531/11190/203068/7532/1454/10382/121441/7277/1781/983/1639/10121/9702/5566/7846/7283/3320/80097/10426/11064/10540/10733/85378/4751/5518/10383/5347/1453/27229/1778 31 Rotavirus_C R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 43/1879 129/10654 1.124841007233661e-5 3.868958629276219e-5 2.026535417890604e-5 8454/1147/3725/8945/1326/351/4790/6885/7321/4214/6500/841/8517/7323/7316/79155/7335/5970/4792/9261/4793/8651/7867/7322/5519/1432/23291/10454/3654/6233/2353/7311/5518/1386/8772/5600/7334/7097/3551/4791/51231/7314/5515 43 Rotavirus_C R-HSA-5655253 Signaling by FGFR2 in disease 20/1879 43/10654 1.1607624043748199e-5 3.97069543791605e-5 2.079824497916344e-5 5295/2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/5439/2885/3845/3265/5432/22916 20 Rotavirus_C R-HSA-75893 TNF signaling 20/1879 43/10654 1.1607624043748199e-5 3.97069543791605e-5 2.079824497916344e-5 7124/1147/7186/6885/55072/9530/841/27005/8517/7316/7128/9099/10616/10454/6233/7311/8772/1540/3551/7314 20 Rotavirus_C R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 12/1879 19/10654 1.2929394240297396e-5 4.375027456446579e-5 2.291610984837917e-5 5295/6464/7316/867/3320/6233/2885/7311/1956/3845/3265/7314 12 Rotavirus_C R-HSA-190872 Transport of connexons to the plasma membrane 12/1879 19/10654 1.2929394240297396e-5 4.375027456446579e-5 2.291610984837917e-5 84617/10382/7277/10381/7278/7846/113457/347733/81027/10383/84790/7280 12 Rotavirus_C R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 12/1879 19/10654 1.2929394240297396e-5 4.375027456446579e-5 2.291610984837917e-5 5295/6464/7316/867/3320/6233/2885/7311/1956/3845/3265/7314 12 Rotavirus_C R-HSA-6804760 Regulation of TP53 Activity through Methylation 12/1879 19/10654 1.2929394240297396e-5 4.375027456446579e-5 2.291610984837917e-5 472/79813/7316/2033/7157/91875/6233/7311/10419/10919/7314/4193 12 Rotavirus_C R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 18/1879 37/10654 1.4648243013815732e-5 4.943288477977708e-5 2.5892624195225427e-5 27161/8841/79718/57690/27327/192670/9611/2874/9612/6907/2033/221656/192669/23028/6256/23112/4343/26523 18 Rotavirus_C R-HSA-9024446 NR1H2 and NR1H3-mediated signaling 21/1879 47/10654 1.5265200850217172e-5 5.137642866793522e-5 2.6910639868945384e-5 5105/27161/8841/79718/57690/27327/192670/9611/2874/2194/9612/6907/2033/221656/192669/23028/6256/23112/4343/26523/29116 21 Rotavirus_C R-HSA-389977 Post-chaperonin tubulin folding pathway 13/1879 22/10654 1.5612045740076273e-5 5.2402898838004003e-5 2.7448298281550778e-5 84617/10382/7277/10381/7278/7846/113457/347733/81027/10383/84790/7280/6904 13 Rotavirus_C R-HSA-8848021 Signaling by PTK6 23/1879 54/10654 1.5954574939200273e-5 5.326700753034331e-5 2.7900912805955843e-5 1019/9021/27043/898/202559/3091/10657/1793/7316/867/2908/595/6233/1398/10656/7311/2034/387/1956/3845/3265/63916/7314 23 Rotavirus_C R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 23/1879 54/10654 1.5954574939200273e-5 5.326700753034331e-5 2.7900912805955843e-5 1019/9021/27043/898/202559/3091/10657/1793/7316/867/2908/595/6233/1398/10656/7311/2034/387/1956/3845/3265/63916/7314 23 Rotavirus_C R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 14/1879 25/10654 1.7062030640470884e-5 5.681293181348284e-5 2.9758244930048606e-5 994/902/891/993/4331/983/5519/5520/7514/5518/5347/7465/1022/5515 14 Rotavirus_C R-HSA-9614085 FOXO-mediated transcription 26/1879 65/10654 1.772078293853914e-5 5.884992105849072e-5 3.0825206675163715e-5 5105/857/2290/65018/10018/7532/10971/23410/4287/1649/7534/694/114907/84676/8850/9314/1387/2908/10628/2033/3066/3065/604/23411/25942/7529 26 Rotavirus_C R-HSA-8854518 AURKA Activation by TPX2 28/1879 73/10654 2.16044780104466e-5 7.155768907163794e-5 3.748145307855258e-5 22981/7531/11190/203068/7532/1454/10382/121441/7277/1781/983/1639/6790/10121/9702/5566/7846/7283/3320/11064/10540/10733/4751/5518/10383/5347/1453/1778 28 Rotavirus_C R-HSA-5689896 Ovarian tumor domain proteases 18/1879 38/10654 2.326795227819041e-5 7.686405343613296e-5 4.026089229082801e-5 7321/55611/7706/8517/7316/79155/983/2099/7415/7128/324/5728/7157/6233/7311/387/54764/7314 18 Rotavirus_C R-HSA-380259 Loss of Nlp from mitotic centrosomes 27/1879 70/10654 2.681039391807034e-5 8.810134694337023e-5 4.614691369238243e-5 22981/7531/11190/203068/7532/1454/10382/121441/7277/1781/983/1639/10121/9702/5566/7846/7283/3320/11064/10540/10733/4751/5518/10383/5347/1453/1778 27 Rotavirus_C R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 27/1879 70/10654 2.681039391807034e-5 8.810134694337023e-5 4.614691369238243e-5 22981/7531/11190/203068/7532/1454/10382/121441/7277/1781/983/1639/10121/9702/5566/7846/7283/3320/11064/10540/10733/4751/5518/10383/5347/1453/1778 27 Rotavirus_C R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 12/1879 20/10654 2.713110533783025e-5 8.868967071269836e-5 4.6455073864142486e-5 1147/7321/8517/7323/7316/7335/7322/6233/7311/7334/3551/7314 12 Rotavirus_C R-HSA-2028269 Signaling by Hippo 12/1879 20/10654 2.713110533783025e-5 8.868967071269836e-5 4.6455073864142486e-5 23286/154796/7531/1856/60485/10413/6789/836/25937/261734/6788/7529 12 Rotavirus_C R-HSA-1226099 Signaling by FGFR in disease 25/1879 63/10654 3.0050359657595896e-5 9.797669346695328e-5 5.131955610384387e-5 5295/2963/5434/5440/11052/5430/5436/9530/5441/2260/5438/5431/5435/4686/5433/2962/2261/5437/11064/5439/2885/3845/3265/5432/22916 25 Rotavirus_C R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 15/1879 29/10654 3.024596393613029e-5 9.810348924361431e-5 5.1385970908669675e-5 5434/5440/8468/5430/5436/5441/5438/5431/5435/5433/5437/3320/54514/5439/5432 15 Rotavirus_C R-HSA-9619483 Activation of AMPK downstream of NMDARs 15/1879 29/10654 3.024596393613029e-5 9.810348924361431e-5 5.1385970908669675e-5 84617/10382/7277/10381/7278/7846/113457/347733/81027/10383/84790/808/801/7280/805 15 Rotavirus_C R-HSA-2173788 Downregulation of TGF-beta receptor signaling 14/1879 26/10654 3.0979048491421574e-5 1.0022162457689873e-4 5.2495436448131763e-005 57154/10273/64750/7316/5501/23327/23645/9958/5499/6233/7514/7311/5500/7314 14 Rotavirus_C R-HSA-5693607 Processing of DNA double-strand break ends 34/1879 98/10654 3.5951797648836144e-5 1.1568525744069398e-4 6.0595186972887454e-5 6118/10111/51720/5982/63967/5531/51548/545/472/7336/580/29086/7316/641/9656/6119/10524/4683/5985/165918/1111/7329/8924/6233/672/5932/7158/7311/6047/9025/79184/7334/83695/7314 34 Rotavirus_C R-HSA-937039 IRAK1 recruits IKK complex 10/1879 15/10654 3.603614249350691e-5 1.1568525744069398e-4 6.0595186972887454e-5 1147/8517/7316/7335/3654/6233/7311/7334/3551/7314 10 Rotavirus_C R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 10/1879 15/10654 3.603614249350691e-5 1.1568525744069398e-4 6.0595186972887454e-5 1147/8517/7316/7335/3654/6233/7311/7334/3551/7314 10 Rotavirus_C R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 18/1879 39/10654 3.613124521950468e-5 1.1569391052383595e-4 6.0599719401672945e-5 6118/5982/7706/7316/5111/5426/9100/10459/7415/6119/5985/25898/9246/6233/7311/7318/5424/7314 18 Rotavirus_C R-HSA-1839126 FGFR2 mutant receptor activation 16/1879 33/10654 4.621066819264228e-5 1.472156655908095e-4 7.711061010852053e-5 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/5439/5432/22916 16 Rotavirus_C R-HSA-5357905 Regulation of TNFR1 signaling 16/1879 33/10654 4.621066819264228e-5 1.472156655908095e-4 7.711061010852053e-5 7124/1147/7186/55072/841/27005/8517/7316/7128/9099/10616/6233/7311/1540/3551/7314 16 Rotavirus_C R-HSA-2995383 Initiation of Nuclear Envelope Reformation 9/1879 13/10654 5.849364561257612e-5 1.8540264381505139e-4 9.711270144339752e-5 4000/7443/8815/5520/2010/4001/5518/7112/5515 9 Rotavirus_C R-HSA-2995410 Nuclear Envelope Reassembly 9/1879 13/10654 5.849364561257612e-5 1.8540264381505139e-4 9.711270144339752e-5 4000/7443/8815/5520/2010/4001/5518/7112/5515 9 Rotavirus_C R-HSA-1236394 Signaling by ERBB4 23/1879 58/10654 6.274683330379793e-5 1.9838140226352275e-4 1.0391089087790034e-4 5295/6464/5241/23385/7316/9611/11059/4734/10413/2099/83737/1742/83464/6233/2885/7311/1956/3845/55851/51107/3265/5663/7314 23 Rotavirus_C R-HSA-5693606 DNA Double Strand Break Response 28/1879 77/10654 6.667424956898728e-5 2.1026740670118912e-4 1.1013670285424653e-4 8467/3838/10111/51720/472/7336/580/29086/7316/9031/8314/9656/10524/4683/165918/7157/7329/8924/6233/672/7158/7311/9025/79184/23030/5536/7334/7314 28 Rotavirus_C R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 16/1879 34/10654 7.307604732653274e-5 2.298774152080879e-4 1.2040829802811398e-4 7321/7706/7323/7316/3093/7322/7128/83737/9246/51191/6233/7311/7318/5094/1540/7314 16 Rotavirus_C R-HSA-110312 Translesion synthesis by REV1 10/1879 16/10654 8.087809964431929e-5 2.5314845188671936e-4 1.325975159958182e-4 6118/5982/7316/5111/10459/6119/5985/6233/7311/7314 10 Rotavirus_C R-HSA-193639 p75NTR signals via NF-kB 10/1879 16/10654 8.087809964431929e-5 2.5314845188671936e-4 1.325975159958182e-4 4790/8878/7316/5970/4792/3654/6233/7311/3551/7314 10 Rotavirus_C R-HSA-75067 Processing of Capped Intronless Pre-mRNA 14/1879 28/10654 9.042145001861369e-5 2.82313355170335e-4 1.4787390303608433e-4 53981/6635/11051/8106/29894/6637/4686/1477/23283/6636/6634/22916/1479/6628 14 Rotavirus_C R-HSA-3214815 HDACs deacetylate histones 32/1879 94/10654 9.153709757287052e-5 2.850856869682435e-4 1.4932603243754473e-4 8841/79718/51742/23186/55869/5978/9112/9219/25855/5931/8819/83933/9611/2874/9612/1108/5926/64426/79685/5928/57459/6907/54815/3066/3065/1107/23028/57504/51317/10284/53615/10362 32 Rotavirus_C R-HSA-110320 Translesion Synthesis by POLH 11/1879 19/10654 9.378335436998687e-5 2.913567237499344e-4 1.5261076080057937e-4 6118/5982/7316/5111/7415/6119/5985/25898/6233/7311/7314 11 Rotavirus_C R-HSA-1474165 Reproduction 44/1879 144/10654 9.700870161894338e-5 3.0063092679929977e-4 1.5746852816206805e-4 4000/7014/6118/10388/117144/25913/8468/1019/25777/10111/23224/27127/93426/10274/7013/545/472/79820/23626/10735/56158/5885/644186/26277/641/9985/6119/23345/4683/256126/10734/65057/8243/9126/7329/4001/50511/6847/672/3306/5932/23353/56979/54386 44 Rotavirus_C R-HSA-9613829 Chaperone Mediated Autophagy 12/1879 22/10654 9.819471048156415e-5 3.0355500622942795e-4 1.590001419883417e-4 1915/1080/10013/7316/3320/6233/3326/7311/7431/3312/11315/7314 12 Rotavirus_C R-HSA-5693532 DNA Double-Strand Break Repair 49/1879 166/10654 1.0527172798137564e-4 3.246310429376411e-4 1.700396332185559e-4 8467/51750/6118/3838/10111/7520/51720/5982/63967/5531/51548/545/472/7336/580/5591/29086/7316/9031/8314/641/5111/5426/9656/6119/22976/10524/4683/5985/165918/1111/7157/7329/79728/8924/6233/672/5932/7158/7311/6047/9025/79184/23030/5536/7334/5424/83695/7314 49 Rotavirus_C R-HSA-9012852 Signaling by NOTCH3 20/1879 49/10654 1.16267868037946e-4 3.5765938767446775e-4 1.8733966581569987e-4 23286/142678/2648/4904/23385/7316/22938/8850/5087/1387/2033/83464/6233/7311/1956/55851/51107/4851/5663/7314 20 Rotavirus_C R-HSA-5656169 Termination of translesion DNA synthesis 15/1879 32/10654 1.2970770051249627e-4 3.9802461039618956e-4 2.0848270748009592e-4 6118/5982/7706/7316/5111/5426/9100/6119/5985/9246/6233/7311/7318/5424/7314 15 Rotavirus_C R-HSA-5693565 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 27/1879 76/10654 1.4106979442270865e-4 4.318322313379737e-4 2.261909198953738e-4 8467/10111/51720/472/7336/580/29086/7316/9031/8314/9656/10524/4683/165918/7157/7329/8924/6233/672/7158/7311/9025/79184/23030/5536/7334/7314 27 Rotavirus_C R-HSA-168898 Toll-like Receptor Cascades 46/1879 155/10654 1.4710872551050084e-4 4.492198154613343e-4 2.3529842360216178e-4 54106/8454/1147/3725/8945/1326/351/4790/6885/7184/7321/6271/4214/6500/841/8517/7323/7316/79155/7335/5970/4792/9261/4793/8651/7867/7322/5519/1432/23291/10454/3654/6233/2353/7311/5518/1386/8772/5600/7334/7097/3551/4791/51231/7314/5515 46 Rotavirus_C R-HSA-5655862 Translesion synthesis by POLK 10/1879 17/10654 1.6536640244140167e-4 5.025212035355216e-4 2.6321734471383045e-4 6118/5982/7316/5111/10459/6119/5985/6233/7311/7314 10 Rotavirus_C R-HSA-5656121 Translesion synthesis by POLI 10/1879 17/10654 1.6536640244140167e-4 5.025212035355216e-4 2.6321734471383045e-4 6118/5982/7316/5111/10459/6119/5985/6233/7311/7314 10 Rotavirus_C R-HSA-1852241 Organelle biogenesis and maintenance 77/1879 296/10654 1.66575400312274e-4 5.049694944091211e-4 2.6449974358237977e-4 10694/84617/5442/8841/79718/22981/7531/11190/203068/7532/10575/1454/10382/85302/23410/150737/121441/57539/7277/10013/55112/26146/10381/585/7278/3313/7203/1781/10576/8766/9611/83658/983/1639/10121/9702/5566/1432/1387/6950/7846/113457/6907/7283/347733/3320/8729/11064/10540/81027/10733/6256/4751/9742/10498/23054/5518/10383/1386/5347/84790/22948/6742/378/808/5600/3054/1453/801/261734/7019/2746/7280/64216/9657/805/1778 77 Rotavirus_C R-HSA-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function 32/1879 97/10654 1.7887798151386481e-4 5.409546687327507e-4 2.833485443252931e-4 55904/9070/84661/11091/8085/3674/57690/5929/27327/192670/865/2623/23309/8850/2033/192669/3065/861/23112/23067/9757/2811/58508/161882/25942/9739/4343/3276/26523/7057/4297/55170 32 Rotavirus_C R-HSA-190828 Gap junction trafficking 19/1879 47/10654 1.9924738350859765e-4 5.997819184984609e-4 3.1416187592445024e-4 1173/84617/71/10382/1601/7277/10381/7278/8218/7846/113457/347733/81027/1213/10383/1211/60/84790/7280 19 Rotavirus_C R-HSA-2559585 Oncogene Induced Senescence 15/1879 33/10654 1.992885607790413e-4 5.997819184984609e-4 3.1416187592445024e-4 1019/57690/27327/5925/192670/7316/192669/7157/23112/6233/7311/4343/26523/7314/4193 15 Rotavirus_C R-HSA-69231 Cyclin D associated events in G1 18/1879 44/10654 2.443285353878286e-4 7.318165701089986e-4 3.8332076944501945e-4 8454/894/1019/902/6500/5925/7316/4331/5519/6502/595/5520/6233/7311/5518/1022/7314/5515 18 Rotavirus_C R-HSA-69236 G1 Phase 18/1879 44/10654 2.443285353878286e-4 7.318165701089986e-4 3.8332076944501945e-4 8454/894/1019/902/6500/5925/7316/4331/5519/6502/595/5520/6233/7311/5518/1022/7314/5515 18 Rotavirus_C R-HSA-176187 Activation of ATR in response to replication stress 16/1879 37/10654 2.5077403301954635e-4 7.493295688316754e-4 3.924939645049048e-4 4172/6118/8318/5982/63967/4173/545/4174/993/4171/4998/6119/5985/4175/1111/4176 16 Rotavirus_C R-HSA-5685942 HDR through Homologous Recombination (HRR) 24/1879 67/10654 2.8174747015236935e-4 8.398757919780153e-4 4.3992148848352405e-4 51750/6118/10111/5982/545/472/580/7316/641/5111/5426/6119/10524/4683/5985/1111/79728/6233/672/5932/7311/5424/83695/7314 24 Rotavirus_C R-HSA-5250924 B-WICH complex positively regulates rRNA expression 30/1879 91/10654 2.851308159001974e-4 8.459331315332872e-4 4.430942836263981e-4 8467/23451/5434/5440/9015/10514/2648/79101/2074/9014/30834/25885/221830/5441/51082/5435/9031/9013/8850/2932/5437/7913/2033/64425/10849/84172/6908/60/9533/9188 30 Rotavirus_C R-HSA-73772 RNA Polymerase I Promoter Escape 30/1879 91/10654 2.851308159001974e-4 8.459331315332872e-4 4.430942836263981e-4 5434/5440/902/9015/79101/9014/30834/25885/404672/221830/5441/51082/11335/5435/4331/9013/7343/2966/5437/2965/64425/2068/2071/10849/2968/84172/2967/6908/1022/9533 30 Rotavirus_C R-HSA-3214841 PKMTs methylate histone lysines 25/1879 71/10654 2.882389519571371e-4 8.47737076327719e-4 4.440391782009155e-4 55904/9070/84661/11091/4790/2146/8085/6839/5929/5931/79813/5970/63976/5928/23512/23067/9757/58508/9739/8726/56979/4297/4791/10919/121536 25 Rotavirus_C R-HSA-933542 TRAF6 mediated NF-kB activation 12/1879 24/10654 2.8981654087419496e-4 8.47737076327719e-4 4.440391782009155e-4 1147/351/7186/4790/4214/7706/8517/5970/4792/4793/3551/4791 12 Rotavirus_C R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 9/1879 15/10654 2.911557051285297e-4 8.47737076327719e-4 4.440391782009155e-4 1499/139285/5519/2932/324/8312/5529/5518/5515 9 Rotavirus_C R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 9/1879 15/10654 2.911557051285297e-4 8.47737076327719e-4 4.440391782009155e-4 1499/139285/5519/2932/324/8312/5529/5518/5515 9 Rotavirus_C R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 9/1879 15/10654 2.911557051285297e-4 8.47737076327719e-4 4.440391782009155e-4 1499/139285/5519/2932/324/8312/5529/5518/5515 9 Rotavirus_C R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 9/1879 15/10654 2.911557051285297e-4 8.47737076327719e-4 4.440391782009155e-4 1499/139285/5519/2932/324/8312/5529/5518/5515 9 Rotavirus_C R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 9/1879 15/10654 2.911557051285297e-4 8.47737076327719e-4 4.440391782009155e-4 1499/139285/5519/2932/324/8312/5529/5518/5515 9 Rotavirus_C R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 9/1879 15/10654 2.911557051285297e-4 8.47737076327719e-4 4.440391782009155e-4 1499/139285/5519/2932/324/8312/5529/5518/5515 9 Rotavirus_C R-HSA-5675482 Regulation of necroptotic cell death 10/1879 18/10654 3.1335794683505155e-4 9.102648478827948e-4 4.767908190944856e-4 7186/841/7316/8797/6233/7311/8772/8743/8795/7314 10 Rotavirus_C R-HSA-2122948 Activated NOTCH1 Transmits Signal to the Nucleus 14/1879 31/10654 3.526229511747344e-4 0.0010219535529415913 5.352926378700281e-4 142678/409/23385/7316/408/83737/83464/6233/7311/55851/51107/4851/5663/7314 14 Rotavirus_C R-HSA-5617833 Cilium Assembly 55/1879 201/10654 3.642619944832717e-4 0.0010532471526398526 5.516840222756248e-4 10694/84617/22981/7531/11190/203068/7532/10575/1454/10382/85302/150737/121441/57539/7277/10013/55112/26146/10381/585/7278/7203/1781/10576/8766/83658/983/1639/10121/9702/5566/6950/7846/113457/7283/347733/3320/8729/11064/10540/81027/10733/4751/9742/5518/10383/5347/84790/22948/378/1453/261734/7280/9657/1778 55 Rotavirus_C R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 25/1879 72/10654 3.6865591776151865e-4 0.0010634958733581137 5.570522356668109e-4 84617/71/7531/7532/10971/10382/7533/7277/10381/7278/7534/8766/7846/113457/347733/81027/9882/10383/60/84790/808/801/7280/7529/805 25 Rotavirus_C R-HSA-157858 Gap junction trafficking and regulation 19/1879 49/10654 3.76916008787646e-4 0.0010848249264416845 5.682242552321922e-4 1173/84617/71/10382/1601/7277/10381/7278/8218/7846/113457/347733/81027/1213/10383/1211/60/84790/7280 19 Rotavirus_C R-HSA-111367 SLBP independent Processing of Histone Pre-mRNAs 7/1879 10/10654 3.8290919327891893e-4 0.0010995465825348772 5.75935363140431e-4 6635/6637/4686/6636/6634/22916/6628 7 Rotavirus_C R-HSA-193704 p75 NTR receptor-mediated signalling 31/1879 97/10654 4.217839727073968e-4 0.001208406255903114 6.329553534787624e-4 8841/4790/10018/7531/8878/7074/11214/23421/23385/9500/7316/5970/4792/836/23365/396/3066/3065/57449/3654/83464/6233/7311/26574/387/55851/51107/3551/5663/7314/84894 31 Rotavirus_C R-HSA-1643713 Signaling by EGFR in Cancer 12/1879 25/10654 4.684145786473223e-4 0.0013328523919691987 6.981394318116789e-4 5295/6464/7316/867/3320/6233/2885/7311/1956/3845/3265/7314 12 Rotavirus_C R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus 12/1879 25/10654 4.684145786473223e-4 0.0013328523919691987 6.981394318116789e-4 142678/4904/23385/7316/83464/6233/7311/1956/55851/51107/5663/7314 12 Rotavirus_C R-HSA-937041 IKK complex recruitment mediated by RIP1 12/1879 25/10654 4.684145786473223e-4 0.0013328523919691987 6.981394318116789e-4 1147/7321/8517/7323/7316/7335/7322/6233/7311/7334/3551/7314 12 Rotavirus_C R-HSA-2132295 MHC class II antigen presentation 37/1879 123/10654 4.7250586323268967e-4 0.0013414452171594728 7.026402978731727e-4 1173/84617/162/1783/10484/10120/10382/10802/1174/821/7277/10381/7278/1780/1781/22872/1639/3109/10121/10112/7846/113457/347733/51143/9632/10540/81027/163/1213/10383/1211/84790/6396/7280/10427/829/1778 37 Rotavirus_C R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 39/1879 132/10654 5.017364641790948e-4 0.0014212082650502868 7.444196646429533e-4 51750/6118/10111/51720/5982/63967/5531/51548/545/472/7336/580/29086/7316/641/5111/5426/9656/6119/10524/4683/5985/165918/1111/7329/79728/8924/6233/672/5932/7158/7311/6047/9025/79184/7334/5424/83695/7314 39 Rotavirus_C R-HSA-5357786 TNFR1-induced proapoptotic signaling 8/1879 13/10654 5.111503082046088e-4 0.0014446053857159599 7.566749245847007e-4 7124/7186/841/27005/7128/9099/8772/1540 8 Rotavirus_C R-HSA-5620912 Anchoring of the basal body to the plasma membrane 31/1879 98/10654 5.144995884287843e-4 0.001450796136740626 7.59917599789314e-4 22981/7531/11190/203068/7532/1454/10382/85302/121441/7277/1781/8766/983/1639/10121/9702/5566/7846/7283/3320/11064/10540/10733/4751/5518/10383/5347/1453/261734/9657/1778 31 Rotavirus_C R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 14/1879 32/10654 5.26001479467587e-4 0.0014798962972885816 7.751600750048651e-4 54778/7316/4609/22938/8812/905/3065/6233/1025/7311/25937/904/7314/4221 14 Rotavirus_C R-HSA-8876725 Protein methylation 10/1879 19/10654 5.573297162406795e-4 0.0015645219837070196 8.194864602736447e-4 1938/1915/79091/7415/151194/808/3312/801/6187/805 10 Rotavirus_C R-HSA-606279 Deposition of new CENPA-containing nucleosomes at the centromere 25/1879 74/10654 5.903979948842375e-4 0.0016499515392746995 8.642339069851503e-4 8467/55839/79682/55320/1058/401541/79019/80152/4869/79172/5931/23421/55355/64105/54069/55166/5928/2491/1060/91687/387103/51773/8607/11339/64946 25 Rotavirus_C R-HSA-774815 Nucleosome assembly 25/1879 74/10654 5.903979948842375e-4 0.0016499515392746995 8.642339069851503e-4 8467/55839/79682/55320/1058/401541/79019/80152/4869/79172/5931/23421/55355/64105/54069/55166/5928/2491/1060/91687/387103/51773/8607/11339/64946 25 Rotavirus_C R-HSA-6804757 Regulation of TP53 Degradation 15/1879 36/10654 6.304967445303887e-4 0.0017580889179332887 9.208755640427432e-4 472/7316/80196/983/5519/1616/9099/7157/6233/7311/5518/7874/7314/4193/5515 15 Rotavirus_C R-HSA-437239 Recycling pathway of L1 18/1879 47/10654 6.358441502096207e-4 0.0017690597245832115 9.266220013581138e-4 1173/84617/71/10382/7277/10381/7278/7846/113457/347733/81027/163/1213/10383/1211/60/84790/7280 18 Rotavirus_C R-HSA-2559580 Oxidative Stress Induced Senescence 37/1879 125/10654 6.642185589344042e-4 0.0018439060660440667 9.658260292125891e-4 1912/3725/1019/2146/8535/6045/57690/27327/80012/5931/192670/7316/9261/1911/7867/5928/1432/84733/23512/57332/192669/7157/23135/23112/6233/2353/7311/4343/8726/648/5600/23466/4217/26523/7314/6015/4193 37 Rotavirus_C R-HSA-6806003 Regulation of TP53 Expression and Degradation 15/1879 37/10654 8.893985932877828e-4 0.002450204241835202 0.0012834010784120826 472/7316/80196/983/5519/1616/9099/7157/6233/7311/5518/7874/7314/4193/5515 15 Rotavirus_C R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 7/1879 11/10654 8.924066567706487e-4 0.002450204241835202 0.0012834010784120826 64344/7422/3091/1387/2033/2034/405 7 Rotavirus_C R-HSA-193692 Regulated proteolysis of p75NTR 7/1879 11/10654 8.924066567706487e-4 0.002450204241835202 0.0012834010784120826 4790/23385/5970/83464/55851/51107/5663 7 Rotavirus_C R-HSA-196025 Formation of annular gap junctions 7/1879 11/10654 8.924066567706487e-4 0.002450204241835202 0.0012834010784120826 1173/71/1601/8218/1213/1211/60 7 Rotavirus_C R-HSA-77588 SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs 7/1879 11/10654 8.924066567706487e-4 0.002450204241835202 0.0012834010784120826 6635/6637/4686/6636/6634/22916/6628 7 Rotavirus_C R-HSA-429914 Deadenylation-dependent mRNA decay 20/1879 56/10654 9.238881561245797e-4 0.0025306195054037163 0.0013255220715205273 5393/1656/9924/9652/26986/10605/23019/55802/1981/1973/10767/196513/1975/55571/9775/56915/29883/118460/80349/22894 20 Rotavirus_C R-HSA-6804758 Regulation of TP53 Activity through Acetylation 13/1879 30/10654 9.25737806289858e-4 0.0025306195054037163 0.0013255220715205273 64769/9219/5931/1108/5928/57459/54815/2033/3066/3065/7157/1107/53615 13 Rotavirus_C R-HSA-5213460 RIPK1-mediated regulated necrosis 10/1879 20/10654 9.394122181831788e-4 0.0025568349938376953 0.0013392535742062252 7186/841/7316/8797/6233/7311/8772/8743/8795/7314 10 Rotavirus_C R-HSA-5218859 Regulated Necrosis 10/1879 20/10654 9.394122181831788e-4 0.0025568349938376953 0.0013392535742062252 7186/841/7316/8797/6233/7311/8772/8743/8795/7314 10 Rotavirus_C R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 9/1879 17/10654 0.0010071771284923387 0.0026981458629823625 0.0014132712902623272 1147/4790/8517/5970/4792/4793/1660/3551/4791 9 Rotavirus_C R-HSA-196299 Beta-catenin phosphorylation cascade 9/1879 17/10654 0.0010071771284923387 0.0026981458629823625 0.0014132712902623272 1499/139285/5519/2932/324/8312/5529/5518/5515 9 Rotavirus_C R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 8/1879 14/10654 0.0010085720957474008 0.0026981458629823625 0.0014132712902623272 139285/5519/2932/324/8312/5529/5518/5515 8 Rotavirus_C R-HSA-4839744 truncated APC mutants destabilize the destruction complex 8/1879 14/10654 0.0010085720957474008 0.0026981458629823625 0.0014132712902623272 139285/5519/2932/324/8312/5529/5518/5515 8 Rotavirus_C R-HSA-4839748 AMER1 mutants destabilize the destruction complex 8/1879 14/10654 0.0010085720957474008 0.0026981458629823625 0.0014132712902623272 139285/5519/2932/324/8312/5529/5518/5515 8 Rotavirus_C R-HSA-5467337 APC truncation mutants have impaired AXIN binding 8/1879 14/10654 0.0010085720957474008 0.0026981458629823625 0.0014132712902623272 139285/5519/2932/324/8312/5529/5518/5515 8 Rotavirus_C R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 8/1879 14/10654 0.0010085720957474008 0.0026981458629823625 0.0014132712902623272 139285/5519/2932/324/8312/5529/5518/5515 8 Rotavirus_C R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 8/1879 14/10654 0.0010085720957474008 0.0026981458629823625 0.0014132712902623272 139285/5519/2932/324/8312/5529/5518/5515 8 Rotavirus_C R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 15/1879 38/10654 0.0012327700182805793 0.003290891392083764 0.001723747551091462 6627/27250/9987/3313/6175/3185/6647/6950/3181/998/5478/4001/552900/5721/829 15 Rotavirus_C R-HSA-5693538 Homology Directed Repair 39/1879 138/10654 0.0012870986224783165 0.003428611649665643 0.0017958845281164416 51750/6118/10111/51720/5982/63967/5531/51548/545/472/7336/580/29086/7316/641/5111/5426/9656/6119/10524/4683/5985/165918/1111/7329/79728/8924/6233/672/5932/7158/7311/6047/9025/79184/7334/5424/83695/7314 39 Rotavirus_C R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 13/1879 31/10654 0.001339654090539666 0.0035500130839950395 0.0018594738114418273 857/1499/139285/1856/5519/2932/324/8312/5529/1855/1857/5518/5515 13 Rotavirus_C R-HSA-70268 Pyruvate metabolism 13/1879 31/10654 0.001339654090539666 0.0035500130839950395 0.0018594738114418273 5161/3945/5160/1737/7416/3939/682/5162/55066/4199/6256/1738/6566 13 Rotavirus_C R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 16/1879 42/10654 0.001341179064480554 0.0035500130839950395 0.0018594738114418273 6118/10111/5982/545/472/580/641/6119/10524/4683/5985/1111/79728/672/5932/83695 16 Rotavirus_C R-HSA-5619102 SLC transporter disorders 30/1879 99/10654 0.0013694705467497117 0.003617251317575188 0.0018946927617700875 23165/6507/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/682/8086/6520/9972/8021/6396/129401/9197/55746/6566/8480 30 Rotavirus_C R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 15/1879 39/10654 0.0016809814249560745 0.004430713145357906 0.002320778787252375 6118/10111/5982/545/472/580/641/6119/10524/4683/5985/1111/672/5932/83695 15 Rotavirus_C R-HSA-176974 Unwinding of DNA 7/1879 12/10654 0.0018161466694577757 0.004739653479907966 0.002482599729260688 4172/8318/4173/4174/4171/4175/4176 7 Rotavirus_C R-HSA-190873 Gap junction degradation 7/1879 12/10654 0.0018161466694577757 0.004739653479907966 0.002482599729260688 1173/71/1601/8218/1213/1211/60 7 Rotavirus_C R-HSA-6802957 Oncogenic MAPK signaling 23/1879 71/10654 0.0018257738353832913 0.004739653479907966 0.002482599729260688 4000/27044/818/71/8087/10018/55750/3674/409/10533/2335/408/56829/60/9444/808/3845/3265/801/4763/5245/7529/805 23 Rotavirus_C R-HSA-4419969 Depolymerisation of the Nuclear Lamina 8/1879 15/10654 0.0018284765421689676 0.004739653479907966 0.002482599729260688 4000/891/983/9663/2010/4001/23175/7112 8 Rotavirus_C R-HSA-5637810 Constitutive Signaling by EGFRvIII 8/1879 15/10654 0.0018284765421689676 0.004739653479907966 0.002482599729260688 5295/6464/867/3320/2885/1956/3845/3265 8 Rotavirus_C R-HSA-5637812 Signaling by EGFRvIII in Cancer 8/1879 15/10654 0.0018284765421689676 0.004739653479907966 0.002482599729260688 5295/6464/867/3320/2885/1956/3845/3265 8 Rotavirus_C R-HSA-8956320 Nucleobase biosynthesis 8/1879 15/10654 0.0018284765421689676 0.004739653479907966 0.002482599729260688 5198/790/2618/10606/7372/3615/5471/8833 8 Rotavirus_C R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 8/1879 15/10654 0.0018284765421689676 0.004739653479907966 0.002482599729260688 54106/7316/7335/3654/6233/7311/7334/7314 8 Rotavirus_C R-HSA-69190 DNA strand elongation 13/1879 32/10654 0.001896363771799512 0.004905469922092952 0.0025694533054177815 4172/6118/8318/5982/4173/4174/5111/4171/6119/5985/4175/5424/4176 13 Saimiriine_herpesvirus_2 R-HSA-453279 Mitotic G1-G1/S phases 51/177 149/10654 5.405857999577243e-55 4.146293085675745e-52 2.4354812882305892e-52 1031/595/3717/6502/1032/8454/6500/896/1869/898/891/1875/5753/1029/7027/1017/993/1030/5925/5933/7465/902/1163/890/5111/1028/9134/4171/3065/990/4609/25/1876/1870/894/5934/1022/1871/8900/55388/5515/1021/4331/1027/983/1874/1026/1019/4067/207/5684 51 Saimiriine_herpesvirus_2 R-HSA-69231 Cyclin D associated events in G1 33/177 44/10654 5.434834057059921e-51 1.3895059072549863e-48 8.161785882181215e-49 1031/595/3717/6502/1032/8454/6500/896/1869/1875/5753/1029/7027/1030/5925/5933/902/1163/1028/25/1870/894/5934/1022/1871/5515/1021/4331/1027/1874/1026/1019/4067 33 Saimiriine_herpesvirus_2 R-HSA-69236 G1 Phase 33/177 44/10654 5.434834057059921e-51 1.3895059072549863e-48 8.161785882181215e-49 1031/595/3717/6502/1032/8454/6500/896/1869/1875/5753/1029/7027/1030/5925/5933/902/1163/1028/25/1870/894/5934/1022/1871/5515/1021/4331/1027/1874/1026/1019/4067 33 Saimiriine_herpesvirus_2 R-HSA-69206 G1/S Transition 38/177 131/10654 1.4799643764377462e-37 2.8378316918193783e-35 1.6669072450404087e-35 595/6502/8454/6500/1869/898/891/1875/5753/7027/1017/993/5925/5933/7465/902/1163/890/5111/9134/4171/3065/990/4609/1876/5934/1022/8900/55388/5515/4331/1027/983/1874/1026/1019/207/5684 38 Saimiriine_herpesvirus_2 R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 30/177 85/10654 1.2566805497973115e-32 1.927747963389076e-30 1.1323353164489457e-30 595/6502/994/8454/6500/1869/898/1875/5753/7027/1017/993/5925/51343/7465/902/1163/890/9134/4609/5934/1022/8900/4331/1027/1874/1026/1019/207/5684 30 Saimiriine_herpesvirus_2 R-HSA-3700989 Transcriptional Regulation by TP53 50/177 365/10654 1.6014712385716613e-32 2.0472140666407737e-30 1.2025082282608264e-30 5728/144455/27327/1869/898/891/79733/8851/1025/905/192670/1029/7027/1017/8621/26523/5933/2810/22974/902/5371/23112/890/5111/9134/27161/4343/57690/1432/1020/6794/192669/3065/51755/7157/5934/1022/8812/8900/995/472/5515/4331/7248/1027/983/1874/904/1026/207 50 Saimiriine_herpesvirus_2 R-HSA-69202 Cyclin E associated events during G1/S transition 28/177 83/10654 7.775303102522492e-30 8.519510685192503e-28 5.004255229894176e-28 595/6502/8454/6500/1869/898/1875/5753/7027/1017/993/5925/7465/902/1163/890/9134/4609/5934/1022/8900/4331/1027/1874/1026/1019/207/5684 28 Saimiriine_herpesvirus_2 R-HSA-69242 S Phase 34/177 161/10654 1.7666951311717909e-28 1.6938189570109544e-26 9.949283107125347e-27 595/6502/994/8454/6500/1869/898/1875/5753/7027/1017/993/5925/51343/7465/902/1163/890/5111/9134/4171/2932/990/4609/5934/1022/8900/4331/1027/1874/1026/1019/207/5684 34 Saimiriine_herpesvirus_2 R-HSA-2559585 Oncogene Induced Senescence 19/177 33/10654 3.8676561914237827e-26 3.2961025542467127e-24 1.9360898829583377e-24 1031/1032/27327/1869/192670/1029/7027/1030/26523/5925/23112/4343/57690/192669/1870/7157/1871/1021/1019 19 Saimiriine_herpesvirus_2 R-HSA-8934593 Regulation of RUNX1 Expression and Activity 15/177 17/10654 1.4698413519166425e-25 1.1273683169200649e-23 6.622022090740242e-24 595/27327/896/192670/865/26523/5371/23112/27161/4343/57690/192669/894/1021/861 15 Saimiriine_herpesvirus_2 R-HSA-1538133 G0 and Early G1 17/177 27/10654 1.8741325065359137e-24 1.306781484102769e-22 7.675872849735606e-23 1869/898/1875/7027/1017/993/5933/890/5111/9134/3065/990/4609/5934/8900/983/1874 17 Saimiriine_herpesvirus_2 R-HSA-2559583 Cellular Senescence 33/177 195/10654 2.2953836549331377e-24 1.4671327194447637e-22 8.617756178170025e-23 1031/1032/27327/1869/898/192670/1029/7027/1017/1030/4217/26523/5925/51343/23112/890/9134/4343/57690/1432/192669/2146/1051/1870/7157/1871/8900/472/1021/1027/5606/1026/1019 33 Saimiriine_herpesvirus_2 R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 20/177 49/10654 1.605426430454308e-23 9.472015939680417e-22 5.563745038335577e-22 144455/1869/898/891/79733/7027/1017/5933/2810/890/5111/9134/7157/5934/8900/995/1027/983/1874/1026 20 Saimiriine_herpesvirus_2 R-HSA-2262752 Cellular responses to stress 45/177 479/10654 3.5996967577190235e-22 1.972119580836065e-20 1.1583986558674752e-20 1031/1032/112398/23411/27327/1869/898/192670/1029/7027/1017/1030/4217/7422/26523/5925/51343/2289/23112/890/3091/9134/367/3320/4343/57690/1432/405/2932/7428/192669/2146/1051/1870/7157/3297/1871/8900/472/1021/1027/5606/1026/1019/5684 45 Saimiriine_herpesvirus_2 R-HSA-8953897 Cellular responses to external stimuli 45/177 493/10654 1.1723369735385e-21 5.99454972469353e-20 3.5211243836805474e-20 1031/1032/112398/23411/27327/1869/898/192670/1029/7027/1017/1030/4217/7422/26523/5925/51343/2289/23112/890/3091/9134/367/3320/4343/57690/1432/405/2932/7428/192669/2146/1051/1870/7157/3297/1871/8900/472/1021/1027/5606/1026/1019/5684 45 Saimiriine_herpesvirus_2 R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 15/177 25/10654 3.1488429763634166e-21 1.509476601794213e-19 8.866478907128568e-20 994/891/1017/993/7465/902/890/2305/9133/1022/8900/995/5515/4331/983 15 Saimiriine_herpesvirus_2 R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 11/177 14/10654 6.791220391646987e-18 3.0640388472901405e-16 1.7997785310370962e-16 144455/1869/898/79733/1017/890/9134/7157/8900/1027/1026 11 Saimiriine_herpesvirus_2 R-HSA-2559580 Oxidative Stress Induced Senescence 22/177 125/10654 7.351477283003416e-17 3.132546153368678e-15 1.840018875511966e-15 1031/1032/27327/1869/192670/1029/7027/1030/4217/26523/23112/4343/57690/1432/192669/2146/1870/7157/1871/1021/5606/1019 22 Saimiriine_herpesvirus_2 R-HSA-69205 G1/S-Specific Transcription 13/177 28/10654 1.4208979337404703e-16 5.735940606204952e-15 3.3692205852682623e-015 1869/898/1875/7027/5933/5111/3065/990/1876/5934/8900/983/1874 13 Saimiriine_herpesvirus_2 R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 13/177 32/10654 1.2443800717826064e-15 4.7721975752862956e-14 2.8031298459102924e-14 1024/1875/892/1025/905/7027/1030/5933/3065/4609/8812/1874/904 13 Saimiriine_herpesvirus_2 R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 11/177 19/10654 1.3121904043471845e-15 4.792619238734717e-14 2.815125278499223e-14 1869/1875/7027/993/5933/5111/3065/990/4609/5934/1874 11 Saimiriine_herpesvirus_2 R-HSA-453274 Mitotic G2-G2/M phases 24/177 198/10654 1.7053929856282802e-14 5.94562009080405e-13 3.4923837217650905e-13 994/8454/6500/1869/891/1017/993/7465/22974/902/890/3320/2305/7157/9133/1022/1871/8900/995/5515/4331/983/1026/5684 24 Saimiriine_herpesvirus_2 R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 15/177 60/10654 3.096704382512091e-14 1.032683591907293e-12 6.065855724096911e-13 595/6502/8454/6500/898/5753/1017/1163/890/9134/8900/1027/1026/1019/5684 15 Saimiriine_herpesvirus_2 R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 10/177 18/10654 4.8433735118983226e-14 1.5478614515108388e-12 9.091946767949483e-13 891/7027/5933/2810/5111/7157/5934/995/983/1874 10 Saimiriine_herpesvirus_2 R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 13/177 44/10654 1.5642644005082254e-13 4.799163180759236e-12 2.818969109126402e-12 1024/1875/892/1025/905/7027/1030/5933/3065/4609/8812/1874/904 13 Saimiriine_herpesvirus_2 R-HSA-1257604 PIP3 activates AKT signaling 26/177 264/10654 1.8789943287416874e-13 5.543033269787978e-12 3.2559092012204137e-12 5728/27327/3082/192670/26523/5371/23112/27161/2264/4343/57690/5156/2932/2261/192669/2146/3065/7157/2064/5515/4233/1027/2309/1026/207/5684 26 Saimiriine_herpesvirus_2 R-HSA-157118 Signaling by NOTCH 24/177 235/10654 7.833392132547203e-13 2.2252636169124835e-11 1.3070923324484221e-11 595/1024/8454/6500/27327/2648/1869/892/192670/7027/26523/23112/3091/27161/4343/57690/192669/3065/4609/7157/1871/861/207/5684 24 Saimiriine_herpesvirus_2 R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 9/177 16/10654 8.142860706855582e-13 2.230562200770797e-11 1.310204655088041e-11 1869/1875/7027/5933/890/3065/5934/983/1874 9 Saimiriine_herpesvirus_2 R-HSA-69275 G2/M Transition 22/177 196/10654 1.1185112560135796e-12 2.95826942538764e-11 1.7376508804857062e-11 994/8454/6500/891/1017/993/7465/22974/902/890/3320/2305/7157/9133/1022/8900/995/5515/4331/983/1026/5684 22 Saimiriine_herpesvirus_2 R-HSA-9006925 Intracellular signaling by second messengers 26/177 305/10654 5.3800237083697204e-12 1.375492728106525e-10 8.07947420063944e-11 5728/27327/3082/192670/26523/5371/23112/27161/2264/4343/57690/5156/2932/2261/192669/2146/3065/7157/2064/5515/4233/1027/2309/1026/207/5684 26 Saimiriine_herpesvirus_2 R-HSA-8878166 Transcriptional regulation by RUNX2 17/177 121/10654 1.2748631771880408e-11 3.154258248074927e-10 1.852772291465132e-10 595/6502/8454/6500/891/865/5925/367/2932/10891/25/861/983/1026/1019/207/5684 17 Saimiriine_herpesvirus_2 R-HSA-8939211 ESR-mediated signaling 22/177 223/10654 1.5197261005017877e-11 3.6425934971402225e-10 2.139614378338043e-10 595/27327/4602/1025/192670/865/26523/2289/23112/27161/3320/4343/57690/192669/3065/2002/4609/1027/2309/861/904/207 22 Saimiriine_herpesvirus_2 R-HSA-5663202 Diseases of signal transduction 28/177 377/10654 2.103742162955548e-11 4.889606784808804e-10 2.872094563779823e-10 22906/1499/3717/1024/5728/8454/6500/2648/3082/11140/892/369/2264/3320/5156/2932/2261/3065/4609/2064/5515/4233/1027/2309/1026/5894/207/5684 28 Saimiriine_herpesvirus_2 R-HSA-69306 DNA Replication 17/177 127/10654 2.8227165680642117e-11 6.195519992867909e-10 3.639171834141859e-10 6502/8454/6500/1869/898/1017/51343/890/5111/9134/4171/990/1870/1871/8900/55388/5684 17 Saimiriine_herpesvirus_2 R-HSA-1912408 Pre-NOTCH Transcription and Translation 15/177 93/10654 2.8271603618041308e-11 6.195519992867909e-10 3.639171834141859e-10 595/27327/2648/1869/192670/7027/26523/23112/27161/4343/57690/192669/7157/1871/861 15 Saimiriine_herpesvirus_2 R-HSA-8878171 Transcriptional regulation by RUNX1 22/177 239/10654 5.985954238600892e-11 1.2753408058352457e-9 7.491194193336789e-10 595/27327/896/4602/192670/865/26523/902/5371/23112/27161/4343/57690/192669/3065/25/894/1022/1021/4331/861/5684 22 Saimiriine_herpesvirus_2 R-HSA-170834 Signaling by TGF-beta Receptor Complex 13/177 73/10654 1.7110050180952316e-10 3.5468671591325476e-9 2.083385911080396e-9 1024/1875/892/1025/905/7027/1030/5933/3065/4609/8812/1874/904 13 Saimiriine_herpesvirus_2 R-HSA-1912422 Pre-NOTCH Expression and Processing 15/177 109/10654 2.9182279784753356e-10 5.890212788133112e-9 3.4598381573059377e-9 595/27327/2648/1869/192670/7027/26523/23112/27161/4343/57690/192669/7157/1871/861 15 Saimiriine_herpesvirus_2 R-HSA-8986944 Transcriptional Regulation by MECP2 12/177 62/10654 3.192486659845215e-10 6.2785570976955896e-9 3.6879468027361725e-9 5728/27327/192670/26523/2289/23112/27161/4343/57690/192669/3065/4233 12 Saimiriine_herpesvirus_2 R-HSA-9018519 Estrogen-dependent gene expression 17/177 150/10654 4.106992278451428e-10 7.875157693930614e-9 4.6257702504663445e-9 595/27327/4602/1025/192670/865/26523/23112/27161/3320/4343/57690/192669/3065/4609/861/904 17 Saimiriine_herpesvirus_2 R-HSA-69620 Cell Cycle Checkpoints 23/177 293/10654 5.238196787060061e-10 9.799260818719674e-9 5.755964633791286e-9 898/891/1029/1017/993/7465/2810/890/9134/4171/7341/990/7157/9133/8900/995/55388/472/5515/1027/983/1026/5684 23 Saimiriine_herpesvirus_2 R-HSA-5683057 MAPK family signaling cascades 23/177 294/10654 5.602557779486262e-10 1.0231337659204674e-8 6.009761227118095e-9 3717/27327/896/3082/192670/26523/369/23112/27161/2264/4343/57690/5156/2261/192669/4609/2064/5515/4233/2309/983/5894/5684 23 Saimiriine_herpesvirus_2 R-HSA-69615 G1/S DNA Damage Checkpoints 12/177 68/10654 9.870563852915123e-10 1.760633133764163e-8 1.0341741319578145e-8 898/1029/1017/993/890/9134/7157/8900/472/1027/1026/5684 12 Saimiriine_herpesvirus_2 R-HSA-5628897 TP53 Regulates Metabolic Genes 13/177 86/10654 1.4310792987781791e-9 2.4946314140065078e-8 1.4653156456389009e-8 5728/27327/192670/26523/2810/23112/27161/4343/57690/192669/7157/7248/207 13 Saimiriine_herpesvirus_2 R-HSA-9022692 Regulation of MECP2 expression and activity 9/177 33/10654 2.1530282540241876e-9 3.669717046303449e-8 2.1555464157248006e-8 27327/192670/26523/23112/27161/4343/57690/192669/3065 9 Saimiriine_herpesvirus_2 R-HSA-5687128 MAPK6/MAPK4 signaling 13/177 89/10654 2.2139002369239715e-9 3.691438003740622e-8 2.1683050375365214e-8 27327/896/192670/26523/23112/27161/4343/57690/192669/4609/2309/983/5684 13 Saimiriine_herpesvirus_2 R-HSA-9006931 Signaling by Nuclear Receptors 22/177 299/10654 4.3144099226409936e-9 7.040749809926898e-8 4.1356493771340314e-8 595/27327/4602/1025/192670/865/26523/2289/23112/27161/3320/4343/57690/192669/3065/2002/4609/1027/2309/861/904/207 22 Saimiriine_herpesvirus_2 R-HSA-6804757 Regulation of TP53 Degradation 9/177 36/10654 5.035166167501198e-9 8.045775938486288e-8 4.725989297566914e-8 1029/1017/890/7157/8900/472/5515/983/207 9 Saimiriine_herpesvirus_2 R-HSA-6806003 Regulation of TP53 Expression and Degradation 9/177 37/10654 6.5592716862634086e-9 1.0267268129314356e-7 6.03086634096829e-8 1029/1017/890/7157/8900/472/5515/983/207 9 Saimiriine_herpesvirus_2 R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 11/177 65/10654 8.015208443644866e-9 1.2054244855442378e-7 7.080514373333339e-8 1025/905/8621/902/51755/7157/1022/8812/472/4331/904 11 Saimiriine_herpesvirus_2 R-HSA-9614085 FOXO-mediated transcription 11/177 65/10654 8.015208443644866e-9 1.2054244855442378e-7 7.080514373333339e-8 23411/1649/2810/6794/10891/3065/5934/1027/2309/1026/207 11 Saimiriine_herpesvirus_2 R-HSA-5633007 Regulation of TP53 Activity 16/177 160/10654 8.668141527012143e-9 1.2785508752342912e-7 7.510049744051005e-8 8851/1029/1017/22974/5371/890/1432/1020/6794/3065/7157/8900/472/5515/983/207 16 Saimiriine_herpesvirus_2 R-HSA-69563 p53-Dependent G1 DNA Damage Response 11/177 66/10654 9.4808911748067e-9 1.3466376909401367e-7 7.90998328034555e-8 898/1029/1017/890/9134/7157/8900/472/1027/1026/5684 11 Saimiriine_herpesvirus_2 R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 11/177 66/10654 9.4808911748067e-9 1.3466376909401367e-7 7.90998328034555e-8 898/1029/1017/890/9134/7157/8900/472/1027/1026/5684 11 Saimiriine_herpesvirus_2 R-HSA-6807070 PTEN Regulation 15/177 140/10654 1.0050382445010527e-8 1.4015715155132863e-7 8.23265777313781e-8 5728/27327/192670/26523/5371/23112/27161/4343/57690/192669/2146/3065/7157/207/5684 15 Saimiriine_herpesvirus_2 R-HSA-9006936 Signaling by TGF-beta family members 13/177 102/10654 1.2209391591315068e-8 1.6722505983104744e-7 9.822593235118138e-8 1024/1875/892/1025/905/7027/1030/5933/3065/4609/8812/1874/904 13 Saimiriine_herpesvirus_2 R-HSA-69052 Switching of origins to a post-replicative state 12/177 90/10654 2.703949730474256e-8 3.6384727074978146e-7 2.1371938774570296e-7 6502/8454/6500/898/1017/51343/890/9134/4171/990/8900/5684 12 Saimiriine_herpesvirus_2 R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 13/177 110/10654 3.0840995695905924e-8 4.0784558101310074e-7 2.395634511406122e-7 1031/1032/1029/1017/1030/51343/890/1051/8900/1021/1027/1026/1019 13 Saimiriine_herpesvirus_2 R-HSA-8878159 Transcriptional regulation by RUNX3 12/177 96/10654 5.6561174984174293e-8 7.352952747942658e-7 4.3190335224311495e-7 595/1499/2648/1029/865/8463/4609/7157/2309/861/1026/5684 12 Saimiriine_herpesvirus_2 R-HSA-69239 Synthesis of DNA 13/177 119/10654 7.978175999192553e-8 1.0198768318967814e-6 5.990630399393706e-7 6502/8454/6500/898/1017/51343/890/5111/9134/4171/990/8900/5684 13 Saimiriine_herpesvirus_2 R-HSA-2219528 PI3K/AKT Signaling in Cancer 12/177 101/10654 1.0043417114187655e-7 1.2628362174724476e-6 7.417743787527723e-7 5728/3082/2264/5156/2932/2261/2064/4233/1027/2309/1026/207 12 Saimiriine_herpesvirus_2 R-HSA-69481 G2/M Checkpoints 15/177 168/10654 1.1815818914148559e-7 1.4617311463148299e-6 8.586028005527306e-7 891/1017/993/7465/2810/4171/7341/990/7157/9133/995/55388/472/983/5684 15 Saimiriine_herpesvirus_2 R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 8/177 37/10654 1.2678759385015446e-7 1.5435886425883885e-6 9.066848816686067e-7 27327/192670/26523/23112/27161/4343/57690/192669 8 Saimiriine_herpesvirus_2 R-HSA-156711 Polo-like kinase mediated events 6/177 16/10654 1.3476224376091665e-7 1.6150412650722355e-6 9.486552685801368e-7 891/993/7465/2305/9133/995 6 Saimiriine_herpesvirus_2 R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 12/177 108/10654 2.1241607308684395e-7 2.506509662424759e-6 1.4722927818812828e-6 595/3717/3082/7422/3091/6935/3320/4609/7157/2309/1026/207 12 Saimiriine_herpesvirus_2 R-HSA-8848021 Signaling by PTK6 9/177 54/10654 2.1999017482130186e-7 2.5183949863871425e-6 1.4792740742107964e-6 595/898/5753/1017/3091/2064/1027/1019/207 9 Saimiriine_herpesvirus_2 R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 9/177 54/10654 2.1999017482130186e-7 2.5183949863871425e-6 1.4792740742107964e-6 595/898/5753/1017/3091/2064/1027/1019/207 9 Saimiriine_herpesvirus_2 R-HSA-9616222 Transcriptional regulation of granulopoiesis 11/177 90/10654 2.600666238871314e-7 2.9333985370798496e-6 1.7230420282305298e-6 1869/4602/865/7027/1017/5371/1051/4609/861/1026/1019 11 Saimiriine_herpesvirus_2 R-HSA-4086398 Ca2+ pathway 9/177 62/10654 7.487460554728332e-7 8.206294765728413e-6 4.820276071820161e-6 1499/27327/192670/26523/23112/27161/4343/57690/192669 9 Saimiriine_herpesvirus_2 R-HSA-2559586 DNA Damage/Telomere Stress Induced Senescence 10/177 80/10654 7.489447634954223e-7 8.206294765728413e-6 4.820276071820161e-6 898/1017/5925/890/9134/7157/8900/472/1027/1026 10 Saimiriine_herpesvirus_2 R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 8/177 47/10654 8.963061223135382e-7 9.548149941867832e-6 5.6084652097981635e-6 1024/8454/6500/2648/892/3091/3065/4609 8 Saimiriine_herpesvirus_2 R-HSA-9024446 NR1H2 and NR1H3-mediated signaling 8/177 47/10654 8.963061223135382e-7 9.548149941867832e-6 5.6084652097981635e-6 27327/192670/26523/23112/27161/4343/57690/192669 8 Saimiriine_herpesvirus_2 R-HSA-113510 E2F mediated regulation of DNA replication 6/177 22/10654 1.1556809578959938e-6 1.1818763929416364e-5 6.9421957891857595e-6 1869/891/7027/5925/5515/983 6 Saimiriine_herpesvirus_2 R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 6/177 22/10654 1.1556809578959938e-6 1.1818763929416364e-5 6.9421957891857595e-6 994/8851/993/1020/995/2309 6 Saimiriine_herpesvirus_2 R-HSA-8863678 Neurodegenerative Diseases 6/177 22/10654 1.1556809578959938e-6 1.1818763929416364e-5 6.9421957891857595e-6 994/8851/993/1020/995/2309 6 Saimiriine_herpesvirus_2 R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 5/177 13/10654 1.3820131908632789e-6 1.3947422597264933e-5 8.192543569106417e-6 891/7465/2810/995/983 5 Saimiriine_herpesvirus_2 R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 10/177 86/10654 1.4780634470960833e-6 1.4534290563111488e-5 8.537262555426771e-6 6502/8454/6500/891/1017/51343/890/8900/983/5684 10 Saimiriine_herpesvirus_2 R-HSA-453276 Regulation of mitotic cell cycle 10/177 86/10654 1.4780634470960833e-6 1.4534290563111488e-5 8.537262555426771e-6 6502/8454/6500/891/1017/51343/890/8900/983/5684 10 Saimiriine_herpesvirus_2 R-HSA-195721 Signaling by WNT 19/177 331/10654 2.4170353859529496e-6 2.3181791598556473e-5 1.3616697734415932e-5 1499/8454/6500/27327/192670/26523/23112/27161/4343/57690/7015/2932/192669/3065/4609/25776/5515/207/5684 19 Saimiriine_herpesvirus_2 R-HSA-68949 Orc1 removal from chromatin 9/177 71/10654 2.4179182892888106e-6 2.3181791598556473e-5 1.3616697734415932e-5 6502/8454/6500/1017/890/4171/990/8900/5684 9 Saimiriine_herpesvirus_2 R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 10/177 92/10654 2.7622221142127954e-6 2.6155856316064372e-5 1.536362657417903e-5 8851/1017/22974/890/1432/1020/6794/7157/8900/472 10 Saimiriine_herpesvirus_2 R-HSA-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function 10/177 97/10654 4.485095276670445e-6 4.195204972202721e-5 2.4642115255647632e-5 27327/192670/865/26523/23112/4343/57690/192669/3065/861 10 Saimiriine_herpesvirus_2 R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 9/177 80/10654 6.623598248907859e-6 6.12084320109919e-5 3.595307610060322e-5 8454/6500/891/1017/51343/890/8900/983/5684 9 Saimiriine_herpesvirus_2 R-HSA-112382 Formation of RNA Pol II elongation complex 8/177 61/10654 6.8859988659160325e-6 6.213601329597172e-5 3.6497925877548756e-5 1025/905/902/4300/1022/8812/4331/904 8 Saimiriine_herpesvirus_2 R-HSA-75955 RNA Polymerase II Transcription Elongation 8/177 61/10654 6.8859988659160325e-6 6.213601329597172e-5 3.6497925877548756e-5 1025/905/902/4300/1022/8812/4331/904 8 Saimiriine_herpesvirus_2 R-HSA-5688426 Deubiquitination 17/177 297/10654 8.77074766260176e-6 7.822283089785524e-5 4.594712361803614e-5 6502/5728/2648/7706/993/890/3091/8678/9817/367/7345/4609/7157/377630/8900/983/5684 17 Saimiriine_herpesvirus_2 R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 22/177 473/10654 1.154966162701343e-5 1.0182287894160116e-4 5.980950001647607e-5 1499/3717/3082/11140/5753/8851/4914/10152/7422/2264/3320/1432/1020/5156/2261/2002/2064/5515/4233/4067/207/5607 22 Saimiriine_herpesvirus_2 R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 7/177 48/10654 1.2858597210878254e-5 1.1207436432663207e-4 6.583109576861115e-5 1025/905/902/1022/8812/4331/904 7 Saimiriine_herpesvirus_2 R-HSA-5689880 Ub-specific processing proteases 14/177 220/10654 1.740925673885649e-5 1.500325833562127e-4 8.812728426056271e-5 6502/5728/2648/993/890/3091/8678/9817/367/4609/7157/377630/8900/5684 14 Saimiriine_herpesvirus_2 R-HSA-68689 CDC6 association with the ORC:origin complex 4/177 11/10654 2.218566232461144e-5 1.8907114447752195e-4 1.110580523384058e-4 1869/990/1870/1871 4 Saimiriine_herpesvirus_2 R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 8/177 72/10654 2.396112016857221e-5 2.0195801284939434e-4 1.1862763946962297e-4 898/1017/51343/890/9134/990/8900/5684 8 Saimiriine_herpesvirus_2 R-HSA-449147 Signaling by Interleukins 21/177 461/10654 2.5302817303217355e-5 2.1094848773443165e-4 1.2390853324687677e-4 595/3717/8454/6500/3082/7422/7132/3091/6935/3320/1432/2002/4609/7157/5515/5606/2309/1026/4067/207/5684 21 Saimiriine_herpesvirus_2 R-HSA-1980143 Signaling by NOTCH1 8/177 73/10654 2.6533144293899493e-5 2.188271147679668e-4 1.2853634134452725e-4 1024/8454/6500/2648/892/3091/3065/4609 8 Saimiriine_herpesvirus_2 R-HSA-176187 Activation of ATR in response to replication stress 6/177 37/10654 2.9279849308973443e-5 2.3891111085087903e-4 1.4033343229832737e-4 1017/993/4171/990/995/55388 6 Saimiriine_herpesvirus_2 R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 6/177 38/10654 3.429450440454527e-5 2.7688299871880237e-4 1.6263764969690167e-4 7329/7422/7341/4609/2064/1026 6 Saimiriine_herpesvirus_2 R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 5/177 24/10654 3.934549655382695e-5 3.143541235081799e-4 1.846477250552405e-4 595/2002/1027/2309/207 5 Saimiriine_herpesvirus_2 R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 7/177 58/10654 4.5664065893208914e-5 3.467756291098142e-4 2.036917165429225e-4 1024/8454/6500/2648/892/3065/4609 7 Saimiriine_herpesvirus_2 R-HSA-2644603 Signaling by NOTCH1 in Cancer 7/177 58/10654 4.5664065893208914e-5 3.467756291098142e-4 2.036917165429225e-4 1024/8454/6500/2648/892/3065/4609 7 Saimiriine_herpesvirus_2 R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 7/177 58/10654 4.5664065893208914e-5 3.467756291098142e-4 2.036917165429225e-4 1024/8454/6500/2648/892/3065/4609 7 Saimiriine_herpesvirus_2 R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 7/177 58/10654 4.5664065893208914e-5 3.467756291098142e-4 2.036917165429225e-4 1024/8454/6500/2648/892/3065/4609 7 Saimiriine_herpesvirus_2 R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 7/177 58/10654 4.5664065893208914e-5 3.467756291098142e-4 2.036917165429225e-4 1024/8454/6500/2648/892/3065/4609 7 Saimiriine_herpesvirus_2 R-HSA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 4/177 13/10654 4.6832117310868405e-5 3.5215915664153004e-4 0.00020685393404594091 1869/7027/5925/5515 4 Saimiriine_herpesvirus_2 R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 5/177 25/10654 4.852392543329246e-5 3.6133835735277004e-4 2.122456830398485e-4 2932/1027/2309/1026/207 5 Saimiriine_herpesvirus_2 R-HSA-198323 AKT phosphorylates targets in the cytosol 4/177 14/10654 6.471659019605667e-5 4.772848526959179e-4 2.8035122068737097e-4 2932/1027/1026/207 4 Saimiriine_herpesvirus_2 R-HSA-674695 RNA Polymerase II Pre-transcription Events 8/177 84/10654 7.368943612719398e-5 5.382837858053122e-4 3.1618123972369946e-4 1025/905/902/4300/1022/8812/4331/904 8 Saimiriine_herpesvirus_2 R-HSA-69002 DNA Replication Pre-Initiation 8/177 85/10654 8.020756106158378e-5 5.803698050399505e-4 3.4090204701447724e-4 1869/1017/4171/990/1870/1871/55388/5684 8 Saimiriine_herpesvirus_2 R-HSA-199418 Negative regulation of the PI3K/AKT network 9/177 110/10654 8.65913969652437e-5 6.207065558162797e-4 3.645953556431314e-4 5728/3082/2264/5156/2261/2064/5515/4233/207 9 Saimiriine_herpesvirus_2 R-HSA-73856 RNA Polymerase II Transcription Termination 7/177 67/10654 1.1649715793915114e-4 8.273455568456382e-4 4.85972549687687e-4 7884/6432/6426/55339/9295/22794/6427 7 Saimiriine_herpesvirus_2 R-HSA-114452 Activation of BH3-only proteins 5/177 30/10654 1.2168398749299867e-4 8.562533798819264e-4 5.029526474843402e-4 1869/7027/2810/7157/207 5 Saimiriine_herpesvirus_2 R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 4/177 17/10654 1.4798122971351732e-4 0.0010318327562751617 6.060858020802432e-4 5934/1027/2309/1026 4 Saimiriine_herpesvirus_2 R-HSA-3858494 Beta-catenin independent WNT signaling 10/177 146/10654 1.5674502410214396e-4 0.0010830939953724722 6.361960200637042e-4 1499/27327/192670/26523/23112/27161/4343/57690/192669/5684 10 Saimiriine_herpesvirus_2 R-HSA-69473 G2/M DNA damage checkpoint 8/177 95/10654 1.7598383018444894e-4 0.0012051749799238602 7.079048808171442e-4 891/7465/2810/7341/7157/995/472/983 8 Saimiriine_herpesvirus_2 R-HSA-167172 Transcription of the HIV genome 7/177 73/10654 2.0076966916754185e-4 0.0013507924232588123 7.934387664238957e-4 1025/905/902/1022/8812/4331/904 7 Saimiriine_herpesvirus_2 R-HSA-8939902 Regulation of RUNX2 expression and activity 7/177 73/10654 2.0076966916754185e-4 0.0013507924232588123 7.934387664238957e-4 6502/8454/6500/865/2932/10891/5684 7 Saimiriine_herpesvirus_2 R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 11/177 182/10654 2.2316043945363922e-4 0.0014883831048777504 8.742578314522433e-4 115426/7329/1029/5371/5111/367/7341/7428/10891/3065/7157 11 Saimiriine_herpesvirus_2 R-HSA-109606 Intrinsic Pathway for Apoptosis 6/177 53/10654 2.3208072962034872e-4 0.0015345337898173058 9.013661731171438e-4 1869/1029/7027/2810/7157/207 6 Saimiriine_herpesvirus_2 R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 7/177 77/10654 2.8028233553319766e-4 0.00183740642182874 0.0010792698120396635 891/3320/7157/9133/983/1026/5684 7 Saimiriine_herpesvirus_2 R-HSA-3232118 SUMOylation of transcription factors 4/177 20/10654 2.8973228502288036e-4 0.0018832598526487224 0.0011062035503103728 7329/1029/7341/7157 4 Saimiriine_herpesvirus_2 R-HSA-2990846 SUMOylation 11/177 188/10654 2.9555996382164216e-4 0.0019049957332033574 0.0011189709377767611 115426/7329/1029/5371/5111/367/7341/7428/10891/3065/7157 11 Saimiriine_herpesvirus_2 R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 8/177 103/10654 3.076183483298557e-4 0.001966193943074994 0.0011549180095191073 3082/2264/5156/2261/2064/5515/4233/207 8 Saimiriine_herpesvirus_2 R-HSA-72187 mRNA 3'-end processing 6/177 58/10654 3.8207582384499467e-4 0.0024219186519761236 0.00142260506833978 6432/6426/55339/9295/22794/6427 6 Saimiriine_herpesvirus_2 R-HSA-195253 Degradation of beta-catenin by the destruction complex 7/177 82/10654 4.13347082810967e-4 0.0025986656763607517 0.0015264240849274708 1499/8454/6500/2932/3065/5515/5684 7 Saimiriine_herpesvirus_2 R-HSA-72202 Transport of Mature Transcript to Cytoplasm 7/177 84/10654 4.789634394007284e-4 0.002986706975775274 0.001754354745943618 7884/6432/6426/55339/9295/22794/6427 7 Saimiriine_herpesvirus_2 R-HSA-2465910 MASTL Facilitates Mitotic Progression 3/177 10/10654 4.964745564156568e-4 0.0030709353610549094 0.001803829457944831 891/5515/983 3 Saimiriine_herpesvirus_2 R-HSA-203927 MicroRNA (miRNA) biogenesis 4/177 24/10654 6.033148548701279e-4 0.0036725594736935563 0.002157216022426188 192670/26523/27161/192669 4 Saimiriine_herpesvirus_2 R-HSA-8940973 RUNX2 regulates osteoblast differentiation 4/177 24/10654 6.033148548701279e-4 0.0036725594736935563 0.002157216022426188 865/5925/367/25 4 Saimiriine_herpesvirus_2 R-HSA-450294 MAP kinase activation 6/177 64/10654 6.519522037196163e-4 0.0039373806319129585 0.0023127686961624183 8454/6500/1432/2002/5515/5606 6 Saimiriine_herpesvirus_2 R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 3/177 11/10654 6.743328916997999e-4 0.0039785640610288196 0.002336959333178254 7422/3091/405 3 Saimiriine_herpesvirus_2 R-HSA-2514853 Condensation of Prometaphase Chromosomes 3/177 11/10654 6.743328916997999e-4 0.0039785640610288196 0.002336959333178254 891/9133/983 3 Saimiriine_herpesvirus_2 R-HSA-9614399 Regulation of localization of FOXO transcription factors 3/177 11/10654 6.743328916997999e-4 0.0039785640610288196 0.002336959333178254 2810/2309/207 3 Saimiriine_herpesvirus_2 R-HSA-5696395 Formation of Incision Complex in GG-NER 5/177 43/10654 6.904334864706868e-4 0.0040424617108627235 0.002374492022574961 7329/902/7341/1022/4331 5 Saimiriine_herpesvirus_2 R-HSA-373755 Semaphorin interactions 6/177 65/10654 7.085001965217977e-4 0.004116815535850142 0.0024181665399627544 8851/3320/1020/2932/2064/4233 6 Saimiriine_herpesvirus_2 R-HSA-212165 Epigenetic regulation of gene expression 9/177 149/10654 8.370639693989795e-4 0.004827278680669302 0.0028354838061160526 23411/2648/6839/902/2932/2146/3065/1022/4331 9 Salivirus_A R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 69/474 129/10654 1.2701705587520753e-59 1.3425702806009437e-56 7.326878591538289e-57 7322/8454/6500/23643/51135/1147/64127/330/7311/1432/3725/11035/8945/23118/1326/329/246330/7187/1386/23291/10333/841/7099/8517/8772/4615/929/9641/4790/114609/6885/5599/353376/5606/7334/3656/7316/6195/7097/57162/3551/79155/10454/7321/5608/8737/10392/7335/5970/4792/8767/7096/57161/3661/9261/695/4793/3654/4791/7189/7314/6233/10010/5515/148022/3146/7867/257397/4214 69 Salivirus_A R-HSA-168898 Toll-like Receptor Cascades 73/474 155/10654 7.602363006469198e-58 4.017848848918971e-55 2.1926815408132214e-55 7322/8454/6500/23643/51135/1147/64127/330/7311/1432/3725/11035/8945/23118/1326/329/246330/7187/1386/23291/10333/841/7099/8517/8772/4615/929/9641/7098/4790/114609/6885/5599/353376/5606/7334/3656/7316/6195/7097/57162/3551/79155/10454/7321/30849/5608/8737/10392/7335/5970/4792/8767/7096/5289/57161/3661/9261/695/4793/3654/6279/4791/7189/7314/6233/10010/5515/148022/3146/7867/257397/4214 73 Salivirus_A R-HSA-166166 MyD88-independent TLR4 cascade 58/474 99/10654 2.880966689860732e-53 7.612954477956984e-51 4.15465722643074e-51 7322/8454/6500/23643/1147/64127/330/7311/1432/3725/11035/8945/23118/1326/329/7187/1386/23291/841/7099/8517/8772/929/9641/4790/6885/5599/353376/5606/7334/3656/7316/6195/3551/79155/10454/7321/5608/8737/10392/7335/5970/4792/8767/3661/9261/4793/3654/4791/7189/7314/6233/10010/5515/148022/3146/7867/257397 58 Salivirus_A R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 58/474 99/10654 2.880966689860732e-53 7.612954477956984e-51 4.15465722643074e-51 7322/8454/6500/23643/1147/64127/330/7311/1432/3725/11035/8945/23118/1326/329/7187/1386/23291/841/7099/8517/8772/929/9641/4790/6885/5599/353376/5606/7334/3656/7316/6195/3551/79155/10454/7321/5608/8737/10392/7335/5970/4792/8767/3661/9261/4793/3654/4791/7189/7314/6233/10010/5515/148022/3146/7867/257397 58 Salivirus_A R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 55/474 94/10654 1.7808385458658452e-50 3.764692685960397e-48 2.05452531186207e-48 7322/8454/6500/1147/64127/330/7311/1432/3725/11035/8945/23118/1326/329/7187/1386/23291/841/8517/8772/9641/7098/4790/6885/5599/5606/7334/3656/7316/6195/3551/79155/10454/7321/5608/8737/10392/7335/5970/4792/8767/3661/9261/4793/3654/4791/7189/7314/6233/10010/5515/148022/3146/7867/257397 55 Salivirus_A R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 55/474 95/10654 4.064767151094269e-50 6.137798398152346e-48 3.349612629773924e-48 8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/23291/10333/7099/8517/4615/929/4790/114609/6885/5599/5606/7334/3656/7316/6195/7097/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/7096/57161/9261/695/4793/3654/4791/7189/7314/6233/5515/3146/7867/257397/4214 55 Salivirus_A R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 55/474 95/10654 4.064767151094269e-50 6.137798398152346e-48 3.349612629773924e-48 8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/23291/10333/7099/8517/4615/929/4790/114609/6885/5599/5606/7334/3656/7316/6195/7097/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/7096/57161/9261/695/4793/3654/4791/7189/7314/6233/5515/3146/7867/257397/4214 55 Salivirus_A R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 55/474 98/10654 4.44669443213237e-49 5.222395571959906e-47 2.850045086325777e-47 8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/23291/10333/7099/8517/4615/929/4790/114609/6885/5599/5606/7334/3656/7316/6195/7097/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/7096/57161/9261/695/4793/3654/4791/7189/7314/6233/5515/3146/7867/257397/4214 55 Salivirus_A R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 55/474 98/10654 4.44669443213237e-49 5.222395571959906e-47 2.850045086325777e-47 8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/23291/10333/7099/8517/4615/929/4790/114609/6885/5599/5606/7334/3656/7316/6195/7097/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/7096/57161/9261/695/4793/3654/4791/7189/7314/6233/5515/3146/7867/257397/4214 55 Salivirus_A R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 54/474 97/10654 6.277079440809125e-48 6.634872968935245e-46 3.620883719540422e-46 8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/23291/7099/8517/4615/929/4790/6885/5599/353376/5606/7334/3656/7316/6195/57162/3551/79155/10454/30849/5608/10392/7335/5970/4792/8767/5289/57161/9261/4793/3654/4791/7189/7314/6233/5515/148022/3146/7867/257397/4214 54 Salivirus_A R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 52/474 92/10654 1.2185695358269675e-46 1.1709345448810043e-44 6.390201967781609e-45 8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/23291/7099/8517/4615/929/4790/6885/5599/353376/5606/7334/3656/7316/6195/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/57161/9261/4793/3654/4791/7189/7314/6233/5515/148022/3146/7867/257397/4214 52 Salivirus_A R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 52/474 93/10654 2.6557917351931543e-46 2.1593629723839723e-44 1.178440381284088e-44 8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/23291/7099/8517/4615/929/4790/6885/5599/353376/5606/7334/3656/7316/6195/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/57161/9261/4793/3654/4791/7189/7314/6233/5515/148022/3146/7867/257397/4214 52 Salivirus_A R-HSA-975155 MyD88 dependent cascade initiated on endosome 52/474 93/10654 2.6557917351931543e-46 2.1593629723839723e-44 1.178440381284088e-44 8454/6500/23643/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/23291/7099/8517/4615/929/4790/6885/5599/353376/5606/7334/3656/7316/6195/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/57161/9261/4793/3654/4791/7189/7314/6233/5515/148022/3146/7867/257397/4214 52 Salivirus_A R-HSA-1632852 Macroautophagy 52/474 95/10654 1.2123076259310752e-45 9.152922575779617e-44 4.995072022633303e-44 2475/51422/7249/8408/7311/1460/5563/23710/64422/7405/84557/5571/10533/5562/53632/84938/11345/115201/55626/84971/26100/9474/7316/65018/6009/83734/5564/9776/11152/23192/5565/8655/30849/79065/5289/57521/7248/55054/9140/81631/55062/140735/11337/22863/440738/8678/6714/8878/7314/6233/60673/9821 52 Salivirus_A R-HSA-9612973 Autophagy 55/474 119/10654 5.431249093732567e-43 3.6043603202344987e-41 1.9670262963586173e-41 2475/51422/7249/8408/7311/1460/5563/23710/64422/7405/84557/5571/10533/3920/5562/53632/84938/11345/115201/55626/3320/84971/26100/9474/7316/65018/6009/83734/5564/9776/11152/23192/5565/8655/30849/79065/5289/57521/7248/55054/9140/81631/55062/140735/11337/22863/440738/8678/6714/8878/7314/6233/60673/9821/3326 55 Salivirus_A R-HSA-73887 Death Receptor Signalling 59/474 141/10654 5.4559853475640475e-43 3.6043603202344987e-41 1.9670262963586173e-41 7124/355/1147/330/7128/7311/7132/4804/57142/23118/329/81858/84894/9099/387/843/841/27005/8517/8772/836/4615/10616/331/396/7186/56957/4790/6885/5599/8717/7316/5584/1540/4803/10018/3551/7185/8743/572/10454/8737/5970/4792/8767/55072/8795/356/65078/4974/3654/7189/7375/8878/7314/4099/6233/8797/257397 59 Salivirus_A R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 47/474 85/10654 1.387039692144861e-41 7.716320813669043e-40 4.211067874212654e-40 8454/6500/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/23291/8517/4615/4790/6885/5599/5606/7334/3656/7316/6195/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/57161/9261/4793/3654/4791/7189/7314/6233/5515/3146/7867/257397/4214 47 Salivirus_A R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 47/474 85/10654 1.387039692144861e-41 7.716320813669043e-40 4.211067874212654e-40 8454/6500/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/23291/8517/4615/4790/6885/5599/5606/7334/3656/7316/6195/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/57161/9261/4793/3654/4791/7189/7314/6233/5515/3146/7867/257397/4214 47 Salivirus_A R-HSA-975871 MyD88 cascade initiated on plasma membrane 47/474 85/10654 1.387039692144861e-41 7.716320813669043e-40 4.211067874212654e-40 8454/6500/51135/1147/64127/7311/1432/3725/8945/23118/1326/246330/1386/23291/8517/4615/4790/6885/5599/5606/7334/3656/7316/6195/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/57161/9261/4793/3654/4791/7189/7314/6233/5515/3146/7867/257397/4214 47 Salivirus_A R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 29/474 30/10654 7.866153383647853e-39 4.157262063257891e-37 2.2687642390731708e-37 7124/1147/330/7128/7311/7132/23118/329/81858/9099/27005/8517/10616/331/7186/56957/6885/8717/7316/1540/3551/7185/10454/8737/55072/7375/7314/6233/257397 29 Salivirus_A R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 36/474 55/10654 7.601847186623802e-36 3.8262630839339805e-34 2.088126445248042e-34 4210/1147/64127/330/7128/7311/1432/23118/29108/329/596/841/8517/598/4790/6885/7334/3656/7316/1540/3551/842/10454/5608/10392/7335/5970/8767/83737/3654/4791/7189/7314/6233/257397/3326 36 Salivirus_A R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 41/474 78/10654 3.7638964251928683e-35 1.8083811461040282e-33 9.868972445003312e-34 7322/1147/7128/7311/84282/1387/54476/23586/79671/7187/843/841/7706/8517/8772/84166/9641/7186/4790/9474/64135/7316/1540/3551/7321/8737/5970/4792/83737/3661/9140/4793/4791/7189/57506/51191/7314/6233/10010/3146/4214 41 Salivirus_A R-HSA-75893 TNF signaling 31/474 43/10654 4.472325916944288e-33 2.0553254322652665e-31 1.121663433631794e-31 7124/1147/330/7128/7311/7132/23118/329/81858/9099/841/27005/8517/8772/10616/331/7186/56957/6885/8717/7316/1540/3551/7185/10454/8737/55072/7375/7314/6233/257397 31 Salivirus_A R-HSA-5357801 Programmed Cell Death 56/474 181/10654 1.492645265668349e-32 6.5738585242143535e-31 3.587585989413401e-31 5716/23643/4000/6093/355/1613/330/7311/23604/7161/11035/329/596/841/7099/999/5588/598/8772/836/331/929/10000/7186/5599/1612/353376/8717/51765/7159/7316/1499/10018/1029/842/8743/572/8655/7082/8737/6774/7157/8795/356/207/8626/54205/140735/208/7314/6233/578/8797/148022/3146/5580 56 Salivirus_A R-HSA-450294 MAP kinase activation 36/474 64/10654 2.0954170632615451e-32 8.859423343469814e-31 4.834899160704534e-31 8454/6500/1147/64127/7311/1432/3725/8945/23118/1326/1386/23291/8517/4790/6885/5599/5606/7334/3656/7316/6195/3551/79155/10454/5608/10392/7335/8767/9261/3654/7189/7314/6233/5515/7867/257397 36 Salivirus_A R-HSA-168638 NOD1/2 Signaling Pathway 28/474 36/10654 1.41496809155351e-31 5.7523895106617694e-30 3.1392814338919977e-30 1147/64127/330/7128/7311/1432/23118/329/841/8517/6885/7334/3656/7316/1540/3551/842/10454/5608/10392/7335/8767/83737/3654/7189/7314/6233/257397 28 Salivirus_A R-HSA-109581 Apoptosis 54/474 178/10654 6.42110735729572e-31 2.5137446209857687e-29 1.3718389207789687e-29 5716/23643/4000/6093/355/1613/7311/23604/7161/329/596/841/7099/999/5588/598/8772/836/331/929/10000/7186/5599/1612/353376/8717/51765/7159/7316/1499/10018/1029/842/8743/572/8655/7082/8737/6774/7157/8795/356/207/8626/54205/140735/208/7314/6233/578/8797/148022/3146/5580 54 Salivirus_A R-HSA-448424 Interleukin-17 signaling 36/474 72/10654 5.968411110836106e-30 2.2530751943406298e-28 1.229582439375258e-28 8454/6500/1147/64127/7311/1432/3725/8945/23118/1326/1386/23291/8517/4790/6885/5599/5606/7334/3656/7316/6195/3551/79155/10454/5608/10392/7335/8767/9261/3654/7189/7314/6233/5515/7867/257397 36 Salivirus_A R-HSA-5357905 Regulation of TNFR1 signaling 26/474 33/10654 1.1736807048202441e-29 4.27786381032758e-28 2.334580857500885e-28 7124/1147/330/7128/7311/7132/329/81858/9099/841/27005/8517/10616/331/7186/56957/8717/7316/1540/3551/7185/8737/55072/7375/7314/6233 26 Salivirus_A R-HSA-450302 activated TAK1 mediates p38 MAPK activation 22/474 24/10654 2.8919596152052882e-28 1.0189337710906633e-26 5.560680242570169e-27 64127/7311/1432/23118/8517/6885/5606/7334/3656/7316/10454/5608/10392/7335/8767/9261/3654/7189/7314/6233/7867/257397 22 Salivirus_A R-HSA-9020702 Interleukin-1 signaling 40/474 103/10654 7.902898226990422e-28 2.694633363202863e-26 1.4705562744960108e-26 5716/8454/6500/51135/1147/64127/7311/8945/23118/1326/246330/23291/8517/4615/4790/6885/7334/3656/7316/4215/57162/3551/79155/10454/5608/10392/7335/5970/4792/8767/57161/4793/3654/4791/7189/8878/7314/6233/3146/257397 40 Salivirus_A R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 25/474 33/10654 8.661336604166198e-28 2.8609477470636475e-26 1.5613198878562753e-26 1147/64127/7311/23118/8517/4790/6885/7334/3656/7316/3551/10454/10392/7335/5970/4792/8767/4793/3654/4791/7189/7314/6233/3146/257397 25 Salivirus_A R-HSA-449147 Signaling by Interleukins 81/474 461/10654 9.10481506293296e-28 2.916299855006103e-26 1.5915274814951394e-26 5716/5295/8454/6500/51135/8660/7124/1147/2308/64127/7311/7132/3091/1432/3725/7291/8945/23118/1326/596/246330/1386/1072/23291/8517/598/1438/5290/836/3576/4615/332/1437/3667/3320/4790/8835/6885/5599/84867/5606/2309/7334/3656/5291/7316/6195/4215/57162/3551/79155/10454/5608/10392/6774/3569/7157/7335/5970/4792/8767/57161/356/4170/9261/207/4793/3654/4791/7189/1439/8878/7314/6233/7525/5515/4582/3146/7867/257397/821 81 Salivirus_A R-HSA-937041 IKK complex recruitment mediated by RIP1 21/474 25/10654 2.8633111079989925e-25 8.901528944573339e-24 4.857877669298601e-24 7322/23643/1147/330/7311/11035/329/7099/8517/929/353376/7334/7316/3551/7321/8737/7335/7189/7314/6233/148022 21 Salivirus_A R-HSA-446652 Interleukin-1 family signaling 43/474 140/10654 5.1489245690504375e-25 1.5549752198532322e-23 8.486047109292151e-24 5716/8454/6500/51135/1147/64127/7311/8945/23118/1326/246330/23291/8517/4615/4790/6885/5599/84867/7334/3656/7316/4215/57162/3551/79155/10454/5608/10392/6774/7335/5970/4792/8767/57161/4793/3654/4791/7189/8878/7314/6233/3146/257397 43 Salivirus_A R-HSA-5260271 Diseases of Immune System 20/474 24/10654 5.633798568780772e-24 1.6094392127571019e-22 8.783276289308289e-23 23643/51135/1147/7187/10333/7099/8517/4615/929/7098/4790/114609/7097/3551/5970/4792/7096/695/4791/148022 20 Salivirus_A R-HSA-5602358 Diseases associated with the TLR signaling cascade 20/474 24/10654 5.633798568780772e-24 1.6094392127571019e-22 8.783276289308289e-23 23643/51135/1147/7187/10333/7099/8517/4615/929/7098/4790/114609/7097/3551/5970/4792/7096/695/4791/148022 20 Salivirus_A R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 23/474 34/10654 8.771729133180217e-24 2.439925708887234e-22 1.3315533421004873e-22 7322/7128/7311/84282/54476/23586/79671/7187/7706/84166/9641/9474/64135/7316/1540/7321/83737/3661/9140/57506/51191/7314/6233 23 Salivirus_A R-HSA-5621481 C-type lectin receptors (CLRs) 42/474 142/10654 9.86469855653668e-24 2.6735862498100695e-22 1.4590701238818086e-22 7322/5716/8454/6500/1147/7311/3384/5170/8945/23118/10892/29108/1387/3708/4893/23291/841/8517/4790/3845/6885/7334/7316/3551/10454/7321/9020/7335/5970/4792/5894/84433/997/8915/4791/7189/6714/7314/6233/4582/257397/5580 42 Salivirus_A R-HSA-5607764 CLEC7A (Dectin-1) signaling 36/474 101/10654 1.2586777836856738e-23 3.326056043389393e-22 1.8151458564730244e-22 7322/5716/8454/6500/1147/7311/5170/8945/23118/10892/29108/3708/23291/841/8517/4790/6885/7334/7316/3551/10454/7321/9020/7335/5970/4792/84433/997/8915/4791/7189/6714/7314/6233/257397/5580 36 Salivirus_A R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 18/474 20/10654 5.967863735470974e-23 1.4669841786960045e-21 8.005849025797048e-22 7322/1147/330/7311/11035/329/8517/7098/7334/7316/3551/7321/8737/7335/7189/7314/6233/148022 18 Salivirus_A R-HSA-5213460 RIPK1-mediated regulated necrosis 18/474 20/10654 5.967863735470974e-23 1.4669841786960045e-21 8.005849025797048e-22 355/330/7311/11035/329/841/8772/331/7186/8717/7316/8743/8737/8795/356/7314/6233/8797 18 Salivirus_A R-HSA-5218859 Regulated Necrosis 18/474 20/10654 5.967863735470974e-23 1.4669841786960045e-21 8.005849025797048e-22 355/330/7311/11035/329/841/8772/331/7186/8717/7316/8743/8737/8795/356/7314/6233/8797 18 Salivirus_A R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 40/474 134/10654 8.155552663860611e-23 1.9591861740228787e-21 1.0691968564104344e-21 7322/5716/5295/8454/6500/1147/7311/5170/3725/8945/23118/10892/3708/4893/23291/8517/5588/5290/4790/3845/6885/5599/7334/5291/7316/3551/10454/7321/7335/5970/4792/695/84433/997/8915/7189/7314/6233/257397/4214 40 Salivirus_A R-HSA-5675482 Regulation of necroptotic cell death 17/474 18/10654 1.3717229185267713e-22 3.2220247219617712e-21 1.7583723025793466e-21 355/330/7311/329/841/8772/331/7186/8717/7316/8743/8737/8795/356/7314/6233/8797 17 Salivirus_A R-HSA-193639 p75NTR signals via NF-kB 16/474 16/10654 1.8449219513859943e-22 4.23930978829347e-21 2.3135405706167622e-21 7311/4804/4615/4790/7316/5584/4803/3551/5970/4792/8767/3654/7189/8878/7314/6233 16 Salivirus_A R-HSA-5689896 Ovarian tumor domain proteases 23/474 38/10654 4.0177400570774736e-22 9.035640936874233e-21 4.931067304095086e-21 64127/7128/7311/84282/23586/7187/387/7706/8517/56957/64135/7316/5728/79155/7321/8737/10392/7157/8767/7189/57506/7314/6233 23 Salivirus_A R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 20/474 27/10654 4.156985928308893e-22 9.154029429630208e-21 4.995676071739635e-21 23643/355/1613/23604/841/7099/8772/836/929/7186/1612/353376/8717/842/8743/8737/8795/356/8797/148022 20 Salivirus_A R-HSA-202424 Downstream TCR signaling 34/474 98/10654 6.227352646824718e-22 1.3433289281007608e-20 7.33101879798055e-21 7322/5716/5295/8454/6500/1147/7311/5170/8945/23118/10892/23291/8517/5588/5290/4790/6885/3115/7334/5291/7316/5728/3551/7321/7335/5970/4792/8767/84433/997/8915/7189/7314/6233 34 Salivirus_A R-HSA-9006925 Intracellular signaling by second messengers 58/474 305/10654 1.0547609486355562e-21 2.229764645415566e-20 1.2168610523205997e-20 2475/5716/5295/7249/51135/8660/1147/2308/7311/818/1460/5170/3725/3708/2064/1386/1956/5290/2260/5581/4615/3164/331/3667/10000/2100/2309/5291/7316/5728/5468/6009/1822/842/2264/572/3630/7157/57521/8658/207/8975/4734/6045/5987/3654/7189/5578/6714/208/5156/4303/10818/7314/6233/253260/5515/5580 58 Salivirus_A R-HSA-1257604 PIP3 activates AKT signaling 53/474 264/10654 5.114083230063808e-21 1.0599188184661656e-19 5.784350072394153e-20 2475/5716/5295/7249/51135/8660/1147/2308/7311/1460/5170/3725/2064/1386/1956/5290/2260/4615/3164/331/3667/10000/2100/2309/5291/7316/5728/5468/6009/1822/842/2264/572/3630/7157/57521/8658/207/8975/4734/6045/5987/3654/7189/6714/208/5156/4303/10818/7314/6233/253260/5515 53 Salivirus_A R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 18/474 23/10654 9.332943302097486e-21 1.8971002058302005e-19 1.0353143582083853e-19 64127/7311/23118/8517/6885/5599/7334/3656/7316/10454/10392/7335/8767/3654/7189/7314/6233/257397 18 Salivirus_A R-HSA-2871837 FCERI mediated NF-kB activation 30/474 82/10654 2.964148045493952e-20 5.911517894503975e-19 3.2261233941026533e-19 7322/5716/8454/6500/1147/7311/5170/8945/23118/10892/23291/8517/5588/4790/6885/7334/7316/3551/10454/7321/7335/5970/4792/84433/997/8915/7189/7314/6233/257397 30 Salivirus_A R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 15/474 16/10654 6.565309512362468e-20 1.2850985471420607e-18 7.013235112621117e-19 23643/7311/23118/7099/929/6885/353376/3656/7316/10454/7189/7314/6233/148022/257397 15 Salivirus_A R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 15/474 17/10654 5.354817113172647e-19 1.0107217301113371e-17 5.515864244395885e-18 23643/355/841/7099/8772/929/7186/353376/8717/8743/8737/8795/356/8797/148022 15 Salivirus_A R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 15/474 17/10654 5.354817113172647e-19 1.0107217301113371e-17 5.515864244395885e-18 23643/7311/23118/7099/929/6885/353376/3656/7316/10454/7189/7314/6233/148022/257397 15 Salivirus_A R-HSA-202403 TCR signaling 34/474 119/10654 6.975519814157503e-19 1.2935306041341193e-17 7.059251815620152e-18 7322/5716/5295/8454/6500/1147/7311/5170/8945/23118/10892/23291/8517/5588/5290/4790/6885/3115/7334/5291/7316/5728/3551/7321/7335/5970/4792/8767/84433/997/8915/7189/7314/6233 34 Salivirus_A R-HSA-5688426 Deubiquitination 53/474 297/10654 1.3445310641116476e-18 2.4502919564931235e-17 1.3372105682997875e-17 5716/672/64127/330/7128/7311/3091/84282/367/9097/23586/329/23032/11274/7187/4287/9099/387/27005/7706/8517/7186/56957/6885/51651/64135/7316/5728/1540/2648/79155/10454/7321/8737/10392/7157/4792/8767/8658/8975/4087/5886/7189/7375/8678/9817/57506/9100/4303/7314/10445/6233/4194 53 Salivirus_A R-HSA-937039 IRAK1 recruits IKK complex 14/474 15/10654 1.4238152742181784e-18 2.5082879080810243e-17 1.3688610004764243e-17 1147/7311/246330/8517/7334/7316/57162/3551/7335/57161/3654/7189/7314/6233 14 Salivirus_A R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 14/474 15/10654 1.4238152742181784e-18 2.5082879080810243e-17 1.3688610004764243e-17 1147/7311/246330/8517/7334/7316/57162/3551/7335/57161/3654/7189/7314/6233 14 Salivirus_A R-HSA-933542 TRAF6 mediated NF-kB activation 17/474 24/10654 2.0572141752257188e-18 3.56471374297309e-17 1.945389763630188e-17 1147/84282/23586/7706/8517/7186/4790/64135/3551/5970/4792/4793/4791/7189/57506/3146/4214 17 Salivirus_A R-HSA-209543 p75NTR recruits signalling complexes 13/474 13/10654 2.2831341795409862e-18 3.77073879339816e-17 2.0578248855073365e-17 7311/4804/4615/7316/5584/4803/3551/8767/3654/7189/8878/7314/6233 13 Salivirus_A R-HSA-209560 NF-kB is activated and signals survival 13/474 13/10654 2.2831341795409862e-18 3.77073879339816e-17 2.0578248855073365e-17 7311/4804/4790/7316/4803/3551/5970/4792/3654/7189/8878/7314/6233 13 Salivirus_A R-HSA-5357786 TNFR1-induced proapoptotic signaling 13/474 13/10654 2.2831341795409862e-18 3.77073879339816e-17 2.0578248855073365e-17 7124/7128/7132/9099/841/27005/8772/7186/56957/8717/1540/8737/7375 13 Salivirus_A R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 14/474 16/10654 1.093095052788002e-17 1.7775407243029508e-16 9.700665407738059e-17 8454/6500/1147/7311/8945/1326/23291/8517/4790/7316/3551/79155/7314/6233 14 Salivirus_A R-HSA-1227986 Signaling by ERBB2 22/474 50/10654 3.1595947708596573e-17 5.060138898179784e-16 2.761495908183561e-16 5295/7311/2064/4893/387/1956/5290/5581/10000/3320/3845/7316/207/11140/5578/6714/10193/208/7314/6233/7525/5580 22 Salivirus_A R-HSA-5663202 Diseases of signal transduction 58/474 377/10654 4.080619530507331e-17 6.437634095143655e-16 3.5132435235161316e-16 2475/5716/5295/7249/8454/6500/4000/5037/8660/1147/2308/7311/818/51009/5170/10533/1387/2064/4893/1956/5290/2260/4140/3164/3667/10000/3320/3845/2100/2309/5291/7316/1499/5728/2648/10018/369/55869/842/2264/572/8315/4296/6774/8658/5894/207/4087/11140/6714/208/5156/4303/10818/7314/6233/253260/5515 58 Salivirus_A R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12/474 12/10654 5.2591155711418267e-17 8.174831115730752e-16 4.461293085117215e-16 1147/84282/23586/843/841/7706/8517/8772/64135/3551/8737/57506 12 Salivirus_A R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 14/474 17/10654 5.944313833850646e-17 9.105999597652366e-16 4.9694645018308995e-016 1147/11035/81030/8517/4615/7098/4790/3551/8737/5970/4792/4793/4791/148022 14 Salivirus_A R-HSA-109606 Intrinsic Pathway for Apoptosis 22/474 53/10654 1.4537917767228634e-16 2.195225582851524e-15 1.1980118701415477e-15 7161/596/841/598/836/331/10000/5599/7159/10018/1029/842/572/8655/6774/7157/207/8626/54205/140735/208/578 22 Salivirus_A R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 15/474 21/10654 1.8113984246306874e-16 2.696687513851601e-15 1.4716772968089204e-15 1147/11035/81030/8517/4615/7098/4790/3551/8737/5970/4792/3661/4793/4791/148022 15 Salivirus_A R-HSA-5633007 Regulation of TP53 Activity 36/474 160/10654 3.0345458342021383e-16 4.454881870488417e-15 2.4311858437759824e-15 2475/51422/672/7311/6119/1460/6118/5170/7161/5563/1432/5571/5562/53632/9099/10000/6117/6794/7159/7316/1029/5564/5565/5608/7157/8445/207/8626/6790/22974/208/7314/6233/253260/5515/4194 36 Salivirus_A R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 23/474 63/10654 8.644891645166186e-16 1.2517329409507752e-14 6.83114725530075e-15 1147/7311/11035/1387/81030/6737/8517/4615/7098/4790/5591/7316/1499/3551/8737/5970/4792/3661/4793/4791/7314/6233/148022 23 Salivirus_A R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 11/474 11/10654 1.2089150545067498e-15 1.7267881251535603e-14 9.423690609810795e-15 7311/23118/7098/6885/7316/10454/7189/7314/6233/148022/257397 11 Salivirus_A R-HSA-2219528 PI3K/AKT Signaling in Cancer 28/474 101/10654 2.188580003024019e-15 3.0844387509285177e-14 1.6832867953082984e-14 2475/5295/7249/8660/1147/2308/5170/2064/1956/5290/2260/3164/3667/10000/2100/2309/5291/5728/842/2264/572/207/6714/208/5156/4303/10818/253260 28 Salivirus_A R-HSA-1169091 Activation of NF-kappaB in B cells 23/474 67/10654 4.134111789102515e-15 5.749679159317576e-14 3.13780229976202e-14 5716/8454/6500/1147/7311/8945/10892/23291/8517/4794/4790/6885/5579/5966/7316/3551/5970/4792/84433/4793/8915/7314/6233 23 Salivirus_A R-HSA-193704 p75 NTR receptor-mediated signalling 27/474 97/10654 6.269898577125926e-15 8.606860774054681e-14 4.6970668766438935e-14 7311/4804/57142/84894/387/836/4615/396/4790/5599/7316/5584/4803/10018/3551/572/5970/4792/8767/65078/4974/3654/7189/8878/7314/4099/6233 27 Salivirus_A R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 25/474 83/10654 8.476542147064879e-15 1.1486801345445612e-13 6.268751817262556e-14 5716/8454/6500/1147/7311/8945/10892/4893/23291/8517/4794/4790/3845/6885/5579/5966/7316/3551/5970/4792/84433/4793/8915/7314/6233 25 Salivirus_A R-HSA-4420097 VEGFA-VEGFR2 Pathway 27/474 99/10654 1.0951838155422876e-14 1.4653282190230354e-13 7.996811870981661e-14 2475/5295/3315/6093/5170/1432/3708/5590/4893/387/5290/10000/3320/3845/5579/5291/1499/8877/9261/207/10458/5578/6714/208/253260/7867/5580 27 Salivirus_A R-HSA-3700989 Transcriptional Regulation by TP53 53/474 365/10654 1.2463086007124912e-14 1.646685238691379e-13 8.986540963032175e-14 2475/51422/7249/672/355/7311/6119/1460/6118/5170/7161/5563/1432/3725/5571/1387/5562/53632/1386/9099/843/332/10000/6117/6794/7159/1874/7316/5728/6009/1029/5564/5565/5608/7157/10397/8795/665/57521/8445/7248/207/8626/54205/6790/22974/208/7314/6233/253260/8797/5515/4194 53 Salivirus_A R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 13/474 18/10654 1.5932119938577076e-14 2.0790433055649345e-13 1.1346071119350538e-13 23643/7311/7187/7099/929/9641/353376/7316/3661/7314/6233/10010/148022 13 Salivirus_A R-HSA-937042 IRAK2 mediated activation of TAK1 complex 10/474 10/10654 2.7732094483124622e-14 3.574734618129601e-13 1.950858507927124e-13 7311/23118/6885/3656/7316/10454/7189/7314/6233/257397 10 Salivirus_A R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 61/474 473/10654 2.8290999176317706e-14 3.602841702333472e-13 1.9661975331163102e-13 2475/5295/3315/8660/6093/7311/5170/1432/23118/3708/2064/1213/4670/5590/4893/387/1956/5290/4914/2260/5581/3667/10000/3320/3845/5579/5291/7316/1499/6195/4803/8471/2264/3630/30849/6774/8877/11059/5289/83737/9261/207/4734/11140/10413/10458/5578/6714/10193/208/5156/10818/7314/6233/253260/7525/5515/7867/3910/5580/5607 61 Salivirus_A R-HSA-983705 Signaling by the B Cell Receptor (BCR) 28/474 112/10654 3.9179517983513856e-14 4.930089346258827e-13 2.690523290095939e-13 5716/5295/8454/6500/1147/7311/8945/10892/3708/4893/23291/8517/4794/4790/3845/6885/5579/5966/7316/3551/5970/4792/695/84433/4793/8915/7314/6233 28 Salivirus_A R-HSA-194138 Signaling by VEGF 27/474 107/10654 8.835551231897843e-14 1.0987267826018848e-12 5.996138792668753e-13 2475/5295/3315/6093/5170/1432/3708/5590/4893/387/5290/10000/3320/3845/5579/5291/1499/8877/9261/207/10458/5578/6714/208/253260/7867/5580 27 Salivirus_A R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 14/474 25/10654 2.803314752074853e-13 3.440698115879473e-12 1.877710070708511e-12 2475/7249/1147/2308/5170/3164/10000/2309/842/572/207/208/4303/253260 14 Salivirus_A R-HSA-3371378 Regulation by c-FLIP 10/474 11/10654 2.9296388876930236e-13 3.440698115879473e-12 1.877710070708511e-12 355/841/8772/7186/8717/8743/8737/8795/356/8797 10 Salivirus_A R-HSA-5218900 CASP8 activity is inhibited 10/474 11/10654 2.9296388876930236e-13 3.440698115879473e-12 1.877710070708511e-12 355/841/8772/7186/8717/8743/8737/8795/356/8797 10 Salivirus_A R-HSA-5603041 IRAK4 deficiency (TLR2/4) 10/474 11/10654 2.9296388876930236e-13 3.440698115879473e-12 1.877710070708511e-12 23643/51135/10333/7099/4615/929/114609/7097/7096/695 10 Salivirus_A R-HSA-69416 Dimerization of procaspase-8 10/474 11/10654 2.9296388876930236e-13 3.440698115879473e-12 1.877710070708511e-12 355/841/8772/7186/8717/8743/8737/8795/356/8797 10 Salivirus_A R-HSA-2262752 Cellular responses to stress 59/474 479/10654 5.923815743840693e-13 6.880739825538035e-12 3.755061917437478e-12 2475/7322/5716/1030/51343/7311/6119/818/3303/3091/6118/7013/367/1432/3725/1387/25913/81929/2034/1019/3576/3309/3320/1780/6117/3490/4790/5599/1021/5606/9448/7316/6195/6009/112399/1029/10935/7321/405/8655/7428/5608/6774/3569/7157/5970/57521/9261/54205/140735/6045/2288/2289/7314/6233/7867/3326/4194/23043 59 Salivirus_A R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 10/474 12/10654 1.6881409429095488e-12 1.9395271485384707e-11 1.0584682342270398e-11 7311/7187/9641/7098/7316/3661/7314/6233/10010/148022 10 Salivirus_A R-HSA-5689880 Ub-specific processing proteases 37/474 220/10654 1.7981905323062944e-12 2.0437498845674765e-11 1.1153462498062811e-11 5716/330/7311/3091/367/9097/23586/329/23032/11274/9099/27005/8517/7186/6885/51651/64135/7316/5728/1540/2648/10454/8737/7157/4792/8658/8975/4087/7189/7375/8678/9817/9100/4303/7314/6233/4194 37 Salivirus_A R-HSA-8953897 Cellular responses to external stimuli 59/474 493/10654 2.049596989846929e-12 2.304706402412983e-11 1.257759406983334e-11 2475/7322/5716/1030/51343/7311/6119/818/3303/3091/6118/7013/367/1432/3725/1387/25913/81929/2034/1019/3576/3309/3320/1780/6117/3490/4790/5599/1021/5606/9448/7316/6195/6009/112399/1029/10935/7321/405/8655/7428/5608/6774/3569/7157/5970/57521/9261/54205/140735/6045/2288/2289/7314/6233/7867/3326/4194/23043 59 Salivirus_A R-HSA-165159 mTOR signalling 16/474 40/10654 4.300040038701402e-12 4.7843603377972444e-11 2.6109938406740928e-11 2475/51422/7249/5563/5571/5562/53632/6198/6794/6009/5564/5565/57521/7248/207/208 16 Salivirus_A R-HSA-193697 p75NTR regulates axonogenesis 9/474 10/10654 6.0989734243370856e-12 6.578178479106428e-11 3.589943540855772e-11 4804/57142/84894/387/396/4803/65078/4974/4099 9 Salivirus_A R-HSA-2562578 TRIF-mediated programmed cell death 9/474 10/10654 6.0989734243370856e-12 6.578178479106428e-11 3.589943540855772e-11 23643/11035/841/7099/8772/929/353376/8737/148022 9 Salivirus_A R-HSA-5602498 MyD88 deficiency (TLR2/4) 9/474 10/10654 6.0989734243370856e-12 6.578178479106428e-11 3.589943540855772e-11 23643/10333/7099/4615/929/114609/7097/7096/695 9 Salivirus_A R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 23/474 92/10654 7.75589339182702e-12 8.280787187031475e-11 4.5191170427657706e-11 51422/672/7311/6119/1460/6118/5563/1432/5571/5562/53632/6117/6794/7316/5564/5565/7157/8445/6790/22974/7314/6233/4194 23 Salivirus_A R-HSA-6804757 Regulation of TP53 Degradation 15/474 36/10654 1.0012094299736753e-11 1.0582783674821749e-10 5.7753975539534114e-11 2475/7311/5170/9099/10000/7316/1029/7157/207/208/7314/6233/253260/5515/4194 15 Salivirus_A R-HSA-6806003 Regulation of TP53 Expression and Degradation 15/474 37/10654 1.6158679305638505e-11 1.6910617847584059e-10 9.228719394986871e-11 2475/7311/5170/9099/10000/7316/1029/7157/207/208/7314/6233/253260/5515/4194 15 Salivirus_A R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 9/474 11/10654 3.222601633439206e-11 3.3394999279855304e-10 1.8224826575074152e-10 7311/23118/6885/7316/10454/7189/7314/6233/257397 9 Salivirus_A R-HSA-983169 Class I MHC mediated antigen processing & presentation 47/474 371/10654 6.152050571050225e-11 6.31331791611659e-10 3.445399808825267e-10 7322/5716/8454/6500/23643/1147/8773/51343/7311/23327/6047/10533/8945/6737/23291/10333/7099/8517/4615/10616/929/3309/8452/9666/114609/9903/7334/7316/7097/3551/7321/135892/7428/7335/7096/11059/83737/695/997/4734/10075/9817/10193/51191/7314/6233/821 47 Salivirus_A R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 11/474 19/10654 6.599818081443145e-11 6.643816868652766e-10 3.6257647204319236e-10 5295/7311/4893/1956/5290/3320/3845/7316/11140/7314/6233 11 Salivirus_A R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 11/474 19/10654 6.599818081443145e-11 6.643816868652766e-10 3.6257647204319236e-10 5295/7311/4893/1956/5290/3320/3845/7316/11140/7314/6233 11 Salivirus_A R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 10/474 15/10654 6.804219478330744e-11 6.784962253392071e-10 3.702792725049899e-10 51135/7311/4615/7334/7316/7335/3654/7189/7314/6233 10 Salivirus_A R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK 13/474 29/10654 8.037967592797457e-11 7.866788653321214e-10 4.293183470616966e-10 2475/51422/7249/5563/5571/5562/53632/6794/6009/5564/5565/57521/7248 13 Salivirus_A R-HSA-5205647 Mitophagy 13/474 29/10654 8.037967592797457e-11 7.866788653321214e-10 4.293183470616966e-10 8408/7311/1460/84557/9474/7316/65018/9140/81631/6714/8878/7314/6233 13 Salivirus_A R-HSA-114452 Activation of BH3-only proteins 13/474 30/10654 1.3615265513269696e-10 1.3203060227088137e-9 7.205374699441617e-10 7161/596/10000/5599/7159/10018/572/8655/7157/207/8626/140735/208 13 Salivirus_A R-HSA-187037 Signaling by NTRK1 (TRKA) 20/474 80/10654 1.83564373903417e-10 1.763886756508289e-9 9.626150899432777e-10 5295/8660/1432/1213/4893/387/5290/4914/3667/3845/5291/6195/4803/6774/9261/6714/10818/5515/7867/5607 20 Salivirus_A R-HSA-199418 Negative regulation of the PI3K/AKT network 23/474 110/10654 3.807808451538743e-10 3.6259941741229295e-9 1.9788326519139225e-9 5295/51135/8660/2064/1956/5290/2260/4615/3667/10000/2100/5291/5728/2264/3630/207/3654/7189/6714/208/5156/10818/5515 23 Salivirus_A R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 9/474 13/10654 3.866714054041659e-10 3.6492113885018157e-9 1.991503103021456e-9 7311/2064/10000/7316/207/10193/208/7314/6233 9 Salivirus_A R-HSA-2559583 Cellular Senescence 31/474 195/10654 5.17371667834679e-10 4.839485423904918e-9 2.6410775405067916e-9 1030/51343/7311/7013/1432/3725/25913/1019/3576/3490/4790/5599/1021/5606/9448/7316/6195/1029/7321/5608/6774/3569/7157/5970/9261/6045/7314/6233/7867/4194/23043 31 Salivirus_A R-HSA-918233 TRAF3-dependent IRF activation pathway 9/474 14/10654 1.0401717954031707e-9 9.644399892466241e-9 5.263288493822139e-9 84282/1387/23586/7187/7706/9641/64135/3661/57506 9 Salivirus_A R-HSA-8863795 Downregulation of ERBB2 signaling 12/474 29/10654 1.3630374769023885e-9 1.2528092287702823e-8 6.837020936773539e-9 7311/2064/1956/10000/3320/7316/207/11140/10193/208/7314/6233 12 Salivirus_A R-HSA-9607240 FLT3 Signaling 36/474 267/10654 2.2158093145195255e-9 2.0190607288337403e-8 1.1018725084906536e-8 5716/5295/5037/8660/7311/818/5170/2064/4893/1956/1438/5290/2260/4140/1437/3667/1843/8452/3845/5291/7316/369/2264/8315/30849/4296/5289/5894/1439/6714/208/5156/10818/7314/6233/5515 36 Salivirus_A R-HSA-1643713 Signaling by EGFR in Cancer 11/474 25/10654 3.0506782092713463e-9 2.7560400574357376e-8 1.5040680689884823e-8 5295/7311/4893/1956/5290/3320/3845/7316/11140/7314/6233 11 Salivirus_A R-HSA-69231 Cyclin D associated events in G1 14/474 44/10654 3.3114704766503727e-9 2.941364952789449e-8 1.6052063876199952e-8 8454/6500/1030/7311/894/1019/1021/1874/7316/1029/6714/7314/6233/5515 14 Salivirus_A R-HSA-69236 G1 Phase 14/474 44/10654 3.3114704766503727e-9 2.941364952789449e-8 1.6052063876199952e-8 8454/6500/1030/7311/894/1019/1021/1874/7316/1029/6714/7314/6233/5515 14 Salivirus_A R-HSA-2428928 IRS-related events triggered by IGF1R 15/474 52/10654 4.169585199165372e-9 3.6727096295981654e-8 2.004326920300547e-8 5295/8660/5170/4893/5290/2260/3667/3845/5291/8471/2264/30849/5289/208/10818 15 Salivirus_A R-HSA-9009391 Extra-nuclear estrogen signaling 18/474 77/10654 4.84598487608704e-9 4.233228110763638e-8 2.3102215851202245e-8 5295/3315/7514/5170/596/5590/4893/1956/5290/10000/3320/3845/2100/2309/8877/207/6714/208 18 Salivirus_A R-HSA-5628897 TP53 Regulates Metabolic Genes 19/474 86/10654 4.968935606271047e-9 4.305053226088932e-8 2.3494190787200468e-8 2475/51422/7249/5563/5571/5562/53632/10000/5728/6009/5564/5565/7157/57521/7248/207/8626/54205/208 19 Salivirus_A R-HSA-205043 NRIF signals cell death from the nucleus 9/474 16/10654 5.486496760777728e-9 4.714818761091105e-8 2.5730425544768465e-8 7311/4804/5599/7316/4803/7189/8878/7314/6233 9 Salivirus_A R-HSA-2428924 IGF1R signaling cascade 15/474 53/10654 5.581061178497428e-9 4.757404569090146e-8 2.5962831288765626e-8 5295/8660/5170/4893/5290/2260/3667/3845/5291/8471/2264/30849/5289/208/10818 15 Salivirus_A R-HSA-5218921 VEGFR2 mediated cell proliferation 10/474 21/10654 6.273279509567651e-9 5.304685153290405e-8 2.8949534073625875e-8 5170/3708/5590/4893/3845/5579/8877/5578/6714/5580 10 Salivirus_A R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 15/474 54/10654 7.416168745191517e-9 6.076659196641422e-8 3.3162468154752774e-8 5295/8660/5170/4893/5290/2260/3667/3845/5291/8471/2264/30849/5289/208/10818 15 Salivirus_A R-HSA-74751 Insulin receptor signalling cascade 15/474 54/10654 7.416168745191517e-9 6.076659196641422e-8 3.3162468154752774e-8 5295/8660/5170/4893/5290/2260/3667/3845/5291/2264/3630/30849/5289/208/10818 15 Salivirus_A R-HSA-8848021 Signaling by PTK6 15/474 54/10654 7.416168745191517e-9 6.076659196641422e-8 3.3162468154752774e-8 7311/3091/2064/2034/1019/4893/387/1956/3845/7316/6774/207/55620/7314/6233 15 Salivirus_A R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 15/474 54/10654 7.416168745191517e-9 6.076659196641422e-8 3.3162468154752774e-8 7311/3091/2064/2034/1019/4893/387/1956/3845/7316/6774/207/55620/7314/6233 15 Salivirus_A R-HSA-389356 CD28 co-stimulation 12/474 33/10654 7.917075622765314e-9 6.437191487125336e-8 3.513001976741208e-8 2475/5295/5170/1326/5290/10000/9020/207/6714/208/253260/7525 12 Salivirus_A R-HSA-5683057 MAPK family signaling cascades 37/474 294/10654 8.9237271514801e-9 7.200289770316387e-8 3.929451570117393e-8 5716/3315/5037/8660/7514/2308/7311/818/3725/2064/4893/1956/1438/2260/4140/1437/3667/1843/8452/3845/2309/7316/369/2264/8315/4296/8202/3569/5597/5894/1439/6714/5156/10818/7314/6233/5515 37 Salivirus_A R-HSA-5675221 Negative regulation of MAPK pathway 13/474 40/10654 9.084951261457864e-9 7.27484354800073e-8 3.9701381908125276e-8 5037/7311/4893/4140/1843/3845/7316/369/8315/5894/7314/6233/5515 13 Salivirus_A R-HSA-6807070 PTEN Regulation 24/474 140/10654 1.0631881653137984e-8 8.449548050651767e-8 4.611215786244255e-8 2475/5716/7311/1460/3725/1386/331/10000/7316/5728/5468/6009/1822/7157/57521/8658/207/8975/4734/6045/5987/208/7314/6233 24 Salivirus_A R-HSA-389357 CD28 dependent PI3K/Akt signaling 10/474 22/10654 1.1046579160171741e-8 8.649062349852986e-8 4.7200977620071074e-8 2475/5295/5170/1326/5290/10000/9020/207/208/253260 10 Salivirus_A R-HSA-5205685 Pink/Parkin Mediated Mitophagy 10/474 22/10654 1.1046579160171741e-8 8.649062349852986e-8 4.7200977620071074e-8 7311/84557/9474/7316/65018/9140/81631/8878/7314/6233 10 Salivirus_A R-HSA-112399 IRS-mediated signalling 14/474 48/10654 1.1790727356877497e-8 9.163822658984937e-8 5.001020581709651e-8 5295/8660/5170/4893/5290/2260/3667/3845/5291/2264/30849/5289/208/10818 14 Salivirus_A R-HSA-166520 Signaling by NTRKs 20/474 101/10654 1.4532755690462773e-8 1.1212498368481131e-7 6.119055027563274e-8 5295/8660/1432/1213/4893/387/5290/4914/3667/3845/5291/6195/4803/6774/9261/6714/10818/5515/7867/5607 20 Salivirus_A R-HSA-1236974 ER-Phagosome pathway 18/474 83/10654 1.727919173761188e-8 1.3188718217974623e-7 7.197547760245077e-8 5716/23643/1147/8773/7311/10333/7099/8517/4615/929/114609/7316/7097/3551/7096/695/7314/6233 18 Salivirus_A R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 20/474 102/10654 1.7343725944167196e-8 1.3188718217974623e-7 7.197547760245077e-8 5716/8454/6500/7124/1147/330/7311/7132/8945/329/7187/23291/7186/958/7316/9020/356/4791/7314/6233 20 Salivirus_A R-HSA-933541 TRAF6 mediated IRF7 activation 11/474 29/10654 2.0132873663083714e-8 1.5200319615628204e-7 8.295349449150283e-8 84282/1387/23586/7706/9641/7186/64135/3661/7189/57506/10010 11 Salivirus_A R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 20/474 103/10654 2.0649543738583464e-8 1.5479835270696966e-7 8.447890980771736e-8 5295/51135/8660/2064/1956/5290/2260/4615/3667/2100/5291/2264/3630/207/3654/7189/6714/5156/10818/5515 20 Salivirus_A R-HSA-1236394 Signaling by ERBB4 15/474 58/10654 2.1628514900473902e-8 1.6099535387183744e-7 8.78608314711616e-8 5295/7311/23118/4893/1956/5290/3845/7316/11059/83737/4734/10413/6714/7314/6233 15 Salivirus_A R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 7/474 10/10654 3.528641908527783e-8 2.608233914205501e-7 1.4234050540104712e-7 51422/5563/1432/5571/53632/5564/5565 7 Salivirus_A R-HSA-8934903 Receptor Mediated Mitophagy 7/474 11/10654 9.33196116964747e-8 6.849918719664845e-7 3.7382417550927004e-7 8408/1460/84557/9474/9140/81631/6714 7 Salivirus_A R-HSA-5654743 Signaling by FGFR4 12/474 41/10654 1.2724831770293098e-7 9.275963573241245e-7 5.062219825858888e-7 5295/7311/4893/5290/3845/7316/2264/6714/10818/7314/6233/5515 12 Salivirus_A R-HSA-9614657 FOXO-mediated transcription of cell death genes 8/474 16/10654 1.3595109861526928e-7 9.842487070982167e-7 5.371391639593913e-7 2308/1387/6794/2309/65018/10018/356/4303 8 Salivirus_A R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 7/474 12/10654 2.1539052117927038e-7 1.5487604141938014e-6 8.452130727263887e-7 355/7161/7159/7157/8795/8626/8797 7 Salivirus_A R-HSA-8948751 Regulation of PTEN stability and activity 15/474 69/10654 2.6223723426694664e-7 1.8728699771632609e-6 1.0220910695468477e-6 5716/7311/1460/331/10000/7316/5728/8658/207/8975/4734/5987/208/7314/6233 15 Salivirus_A R-HSA-1236975 Antigen processing-Cross presentation 18/474 99/10654 3.0022991415444914e-7 2.1052311493217412e-6 1.1488987400570775e-6 5716/23643/1147/8773/7311/10333/7099/8517/4615/929/114609/7316/7097/3551/7096/695/7314/6233 18 Salivirus_A R-HSA-109704 PI3K Cascade 12/474 44/10654 3.0074730704596304e-7 2.1052311493217412e-6 1.1488987400570775e-6 5295/8660/5170/5290/2260/3667/5291/2264/30849/5289/208/10818 12 Salivirus_A R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 12/474 44/10654 3.0074730704596304e-7 2.1052311493217412e-6 1.1488987400570775e-6 355/7161/1387/843/332/7159/7157/10397/8795/665/8626/8797 12 Salivirus_A R-HSA-111465 Apoptotic cleavage of cellular proteins 11/474 38/10654 4.863863275837262e-7 3.3601983546143697e-6 1.8337785174811279e-6 4000/6093/329/841/999/5588/836/51765/1499/7082/5580 11 Salivirus_A R-HSA-5696394 DNA Damage Recognition in GG-NER 11/474 38/10654 4.863863275837262e-7 3.3601983546143697e-6 1.8337785174811279e-6 7311/8533/1642/7316/10987/5886/50813/7314/10445/6233/51138 11 Salivirus_A R-HSA-170834 Signaling by TGF-beta Receptor Complex 15/474 73/10654 5.708737294113315e-7 3.91826968823232e-6 2.1383376877471614e-6 7514/1030/7311/23327/23645/5590/387/1874/7316/23439/7321/4087/5499/7314/6233 15 Salivirus_A R-HSA-2559580 Oxidative Stress Induced Senescence 20/474 125/10654 5.760605230800758e-7 3.928361115455743e-6 2.143844934790367e-6 1030/7311/1432/3725/1019/5599/1021/5606/9448/7316/1029/5608/7157/9261/6045/7314/6233/7867/4194/23043 20 Salivirus_A R-HSA-453279 Mitotic G1-G1/S phases 22/474 149/10654 6.581282478592195e-7 4.459240756328173e-6 2.433564641206831e-6 5716/8454/6500/1030/7311/6119/6118/894/1019/10000/6117/1021/1874/7316/1029/207/6714/208/7314/6233/5515/7298 22 Salivirus_A R-HSA-5686938 Regulation of TLR by endogenous ligand 8/474 19/10654 7.091261517874799e-7 4.7741805250915045e-6 2.6054383585621123e-6 23643/10333/7099/929/7097/7096/6279/3146 8 Salivirus_A R-HSA-5673000 RAF activation 10/474 32/10654 7.368949663964172e-7 4.929734047348183e-6 2.6903293909742615e-6 818/4893/4140/3845/369/8315/4296/5894/6714/5515 10 Salivirus_A R-HSA-9614085 FOXO-mediated transcription 14/474 65/10654 7.429742288884794e-7 4.939143144246054e-6 2.6954642663415208e-6 2308/1387/4287/10000/6794/2309/65018/10018/3630/356/207/4087/208/4303 14 Salivirus_A R-HSA-5654741 Signaling by FGFR3 11/474 40/10654 8.618449750638779e-7 5.632784933566735e-6 3.0740090062187636e-6 5295/7311/4893/5290/3845/7316/6714/10818/7314/6233/5515 11 Salivirus_A R-HSA-198323 AKT phosphorylates targets in the cytosol 7/474 14/10654 8.633028942647219e-7 5.632784933566735e-6 3.0740090062187636e-6 7249/1147/10000/842/572/207/208 7 Salivirus_A R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 7/474 14/10654 8.633028942647219e-7 5.632784933566735e-6 3.0740090062187636e-6 7161/10000/7159/7157/207/8626/208 7 Salivirus_A R-HSA-2173788 Downregulation of TGF-beta receptor signaling 9/474 26/10654 1.00501535495641e-6 6.517185461281751e-6 3.5566575041402176e-6 7514/7311/23327/23645/7316/4087/5499/7314/6233 9 Salivirus_A R-HSA-2559585 Oncogene Induced Senescence 10/474 33/10654 1.015643598599647e-6 6.542962945397155e-6 3.57072518456171e-6 1030/7311/1019/1021/7316/1029/7157/7314/6233/4194 10 Salivirus_A R-HSA-5684996 MAPK1/MAPK3 signaling 30/474 255/10654 1.021370753065781e-6 6.542962945397155e-6 3.57072518456171e-6 5716/5037/8660/7311/818/2064/4893/1956/1438/2260/4140/1437/3667/1843/8452/3845/7316/369/2264/8315/4296/3569/5894/1439/6714/5156/10818/7314/6233/5515 30 Salivirus_A R-HSA-167044 Signalling to RAS 8/474 20/10654 1.1361139896830478e-6 7.190853216137614e-6 3.924301710345479e-6 1432/4893/4914/3845/4803/9261/6714/7867 8 Salivirus_A R-HSA-622312 Inflammasomes 8/474 20/10654 1.1361139896830478e-6 7.190853216137614e-6 3.924301710345479e-6 4210/29108/596/598/4790/5970/4791/3326 8 Salivirus_A R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 18/474 108/10654 1.146826930526413e-6 7.2154527712286825e-6 3.937726553436557e-6 5295/7124/2308/3091/7291/596/598/3576/332/3320/2309/6774/3569/7157/356/4170/207/4582 18 Salivirus_A R-HSA-5654736 Signaling by FGFR1 12/474 50/10654 1.3566128101227094e-6 8.484850534317774e-6 4.630481594190251e-6 5295/7311/4893/5290/2260/3845/7316/6714/10818/7314/6233/5515 12 Salivirus_A R-HSA-74752 Signaling by Insulin receptor 15/474 78/10654 1.3966257914964964e-6 8.683726244775275e-6 4.73901506959802e-6 5295/8660/5170/4893/5290/2260/3667/3845/5291/2264/3630/30849/5289/208/10818 15 Salivirus_A R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 18/474 110/10654 1.5123561669513742e-6 9.348306833143875e-6 5.1017000891926945e-6 1030/51343/7311/3725/1019/3576/3490/4790/1021/7316/6195/1029/7321/6774/3569/5970/7314/6233 18 Salivirus_A R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 7/474 15/10654 1.5568139787693325e-6 9.457197560684969e-6 5.161125592048363e-6 7311/81030/6737/7316/3661/7314/6233 7 Salivirus_A R-HSA-5637810 Constitutive Signaling by EGFRvIII 7/474 15/10654 1.5568139787693325e-6 9.457197560684969e-6 5.161125592048363e-6 5295/4893/1956/5290/3320/3845/11140 7 Salivirus_A R-HSA-5637812 Signaling by EGFRvIII in Cancer 7/474 15/10654 1.5568139787693325e-6 9.457197560684969e-6 5.161125592048363e-6 5295/4893/1956/5290/3320/3845/11140 7 Salivirus_A R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 13/474 60/10654 1.7239115635726464e-6 1.0412425843978784e-5 5.682427289249987e-6 5716/8454/6500/1147/7311/8945/23291/7316/9020/5970/4791/7314/6233 13 Salivirus_A R-HSA-5673001 RAF/MAP kinase cascade 29/474 249/10654 1.9063171927622517e-6 1.144873450425966e-5 6.247977402115514e-6 5716/5037/8660/7311/818/2064/4893/1956/1438/2260/4140/1437/3667/1843/8452/3845/7316/369/2264/8315/4296/5894/1439/6714/5156/10818/7314/6233/5515 29 Salivirus_A R-HSA-388841 Costimulation by the CD28 family 14/474 70/10654 1.918679888512478e-6 1.1457879334224234e-5 6.252968057715361e-6 2475/5295/5170/1326/5290/10000/3115/9020/207/6714/208/253260/7525/5515 14 Salivirus_A R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 15/474 80/10654 1.954728836421938e-6 1.1607575169089823e-5 6.334662343933898e-6 7311/23586/81929/5610/11274/7706/7334/7316/3661/2316/4734/5495/51191/7314/6233 15 Salivirus_A R-HSA-8939211 ESR-mediated signaling 27/474 223/10654 2.049907413944504e-6 1.2104760539325927e-5 6.605993900862031e-6 5295/3315/7514/5170/3725/1387/596/5590/1386/4893/1956/5290/10000/3320/3845/2100/2309/8243/9126/8202/8877/207/2288/2289/6714/208/3326 27 Salivirus_A R-HSA-75153 Apoptotic execution phase 12/474 52/10654 2.1264020121955437e-6 1.248670514939272e-5 6.81443451861496e-6 4000/6093/329/841/999/5588/836/51765/1499/7082/3146/5580 12 Salivirus_A R-HSA-110312 Translesion synthesis by REV1 7/474 16/10654 2.661929552222486e-6 1.5478176993056736e-5 8.446986000293875e-6 7311/6119/6118/6117/7316/7314/6233 7 Salivirus_A R-HSA-912631 Regulation of signaling by CBL 8/474 22/10654 2.6651165683408953e-6 1.5478176993056736e-5 8.446986000293875e-6 5295/7311/5290/5291/7316/7314/6233/7525 8 Salivirus_A R-HSA-1169408 ISG15 antiviral mechanism 14/474 72/10654 2.73389645344584e-6 1.5790866400504115e-5 8.617631616268741e-6 7311/23586/81929/5610/11274/7706/7334/7316/3661/4734/5495/51191/7314/6233 14 Salivirus_A R-HSA-5655291 Signaling by FGFR4 in disease 6/474 11/10654 2.8693894613233686e-6 1.6394295462804328e-5 8.94694409561995e-6 5295/4893/5290/3845/2264/10818 6 Salivirus_A R-HSA-9614399 Regulation of localization of FOXO transcription factors 6/474 11/10654 2.8693894613233686e-6 1.6394295462804328e-5 8.94694409561995e-6 2308/10000/2309/207/208/4303 6 Salivirus_A R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 15/474 84/10654 3.7030716704111444e-6 2.104379976142247e-5 1.148434224892647e-5 7311/6119/6118/8533/1642/6117/7334/7316/10987/5886/50813/7314/10445/6233/51138 15 Salivirus_A R-HSA-8854214 TBC/RABGAPs 11/474 46/10654 3.903099589700898e-6 2.2061905167453738e-5 1.2039958205213015e-5 7249/8408/11345/338382/5868/9363/7248/81631/7879/11337/51256 11 Salivirus_A R-HSA-5655862 Translesion synthesis by POLK 7/474 17/10654 4.352492514823286e-6 2.4341717397715417e-5 1.3284131986205296e-5 7311/6119/6118/6117/7316/7314/6233 7 Salivirus_A R-HSA-5656121 Translesion synthesis by POLI 7/474 17/10654 4.352492514823286e-6 2.4341717397715417e-5 1.3284131986205296e-5 7311/6119/6118/6117/7316/7314/6233 7 Salivirus_A R-HSA-8878159 Transcriptional regulation by RUNX3 16/474 96/10654 4.51184097430933e-6 2.5100083736026116e-5 1.3697999190700903e-5 5716/7311/8463/1387/3845/2309/7316/1499/2648/10018/1029/7157/10413/6714/7314/6233 16 Salivirus_A R-HSA-5689877 Josephin domain DUBs 6/474 12/10654 5.523388401467474e-6 3.0407403855995418e-5 1.6594390592128157e-5 7311/4287/7316/5886/7314/6233 6 Salivirus_A R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 6/474 12/10654 5.523388401467474e-6 3.0407403855995418e-5 1.6594390592128157e-5 5295/8660/23533/5290/5294/5291 6 Salivirus_A R-HSA-3371571 HSF1-dependent transactivation 8/474 24/10654 5.665010730279118e-6 3.086554815414963e-5 1.684441606181746e-5 2475/818/3303/1387/3320/57521/2288/3326 8 Salivirus_A R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 8/474 24/10654 5.665010730279118e-6 3.086554815414963e-5 1.684441606181746e-5 1432/5590/5579/30849/5289/6279/5578/5580 8 Salivirus_A R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 11/474 48/10654 6.098168215165335e-6 3.305519899194748e-5 1.8039385597358186e-5 5295/7311/1438/5290/1437/5291/7316/1439/7314/6233/7525 11 Salivirus_A R-HSA-2173789 TGF-beta receptor signaling activates SMADs 9/474 32/10654 7.104352969111895e-6 3.786701843696512e-5 2.066536483937349e-5 7514/7311/23327/23645/7316/4087/5499/7314/6233 9 Salivirus_A R-HSA-397795 G-protein beta:gamma signalling 9/474 32/10654 7.104352969111895e-6 3.786701843696512e-5 2.066536483937349e-5 5170/146850/23533/387/10000/5294/207/695/208 9 Salivirus_A R-HSA-5656169 Termination of translesion DNA synthesis 9/474 32/10654 7.104352969111895e-6 3.786701843696512e-5 2.066536483937349e-5 7311/6119/6118/7706/6117/7316/9100/7314/6233 9 Salivirus_A R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 32/474 309/10654 7.129173764386054e-6 3.786701843696512e-5 2.066536483937349e-5 7322/5716/8454/6500/51343/7311/23327/6047/10533/8945/6737/23291/10616/8452/9666/9903/7334/7316/7321/135892/7428/7335/11059/83737/997/4734/10075/9817/10193/51191/7314/6233 32 Salivirus_A R-HSA-392451 G beta:gamma signalling through PI3Kgamma 8/474 25/10654 8.009081332164054e-6 4.211740780147963e-5 2.2984951924723236e-5 5170/146850/23533/387/10000/5294/207/208 8 Salivirus_A R-HSA-9006335 Signaling by Erythropoietin 8/474 25/10654 8.009081332164054e-6 4.211740780147963e-5 2.2984951924723236e-5 5295/8660/23533/4893/5290/5294/3845/5291 8 Salivirus_A R-HSA-5676590 NIK-->noncanonical NF-kB signaling 12/474 59/10654 8.683978537254626e-6 4.5440422345931386e-5 2.4798437928168503e-5 5716/8454/6500/1147/7311/8945/23291/7316/9020/4791/7314/6233 12 Salivirus_A R-HSA-171007 p38MAPK events 6/474 13/10654 9.87301954765793e-6 5.140779143780508e-5 2.805504128657789e-5 1432/4893/3845/9261/6714/7867 6 Salivirus_A R-HSA-110320 Translesion Synthesis by POLH 7/474 19/10654 1.043292841307091e-5 5.4056888885372316e-5 2.950074700909628e-5 7311/6119/6118/6117/7316/7314/6233 7 Salivirus_A R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 10/474 42/10654 1.1252709808378635e-5 5.8020069597347406e-5 3.16635942233196e-5 7514/7311/8945/331/7316/1499/207/208/7314/6233 10 Salivirus_A R-HSA-187687 Signalling to ERKs 9/474 34/10654 1.2269577510652751e-5 6.295603606194154e-5 3.435732486375937e-5 1432/4893/4914/3845/4803/9261/6714/10818/7867 9 Salivirus_A R-HSA-6802957 Oncogenic MAPK signaling 13/474 71/10654 1.2388255652055956e-5 6.325790446484611e-5 3.4522065076667504e-5 4000/5037/818/10533/4893/4140/3845/10018/369/8315/4296/5894/6714 13 Salivirus_A R-HSA-5696395 Formation of Incision Complex in GG-NER 10/474 43/10654 1.4086999782785669e-5 7.158634024232909e-5 3.90671856324218e-5 7311/6119/6118/1642/6117/7334/7316/5886/7314/6233 10 Salivirus_A R-HSA-8876384 Listeria monocytogenes entry into host cells 7/474 20/10654 1.5438905410279753e-5 7.80809713811756e-5 4.261153444892121e-5 7311/999/7316/1499/6714/7314/6233 7 Salivirus_A R-HSA-114604 GPVI-mediated activation cascade 9/474 35/10654 1.587327815104107e-5 7.989550002690673e-5 4.360178660035342e-5 5295/5170/146850/5590/23533/387/5290/5294/5291 9 Salivirus_A R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 6/474 14/10654 1.6630307037702854e-5 8.33091684305778e-5 4.5464745605693015e-5 7161/332/7159/7157/10397/8626 6 Salivirus_A R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 10/474 44/10654 1.7514797340046617e-5 8.73261357944777e-5 4.765694608910401e-5 1030/7311/23327/1874/7316/23439/7321/4087/7314/6233 10 Salivirus_A R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 22/474 182/10654 1.8629348041279205e-5 9.244704638324939e-5 5.045160724794171e-5 672/367/1387/81929/7155/8517/332/9641/6117/8243/9126/7022/5468/1029/7428/7157/5970/4792/6045/6790/5987/4791 22 Salivirus_A R-HSA-5621575 CD209 (DC-SIGN) signaling 7/474 21/10654 2.2276242271912616e-5 1.1002798168883943e-4 6.0046142474216006e-5 3384/1387/4893/4790/3845/5970/5894 7 Salivirus_A R-HSA-195258 RHO GTPase Effectors 32/474 327/10654 2.2702832652980392e-5 1.1161346099628035e-4 6.091139433945291e-5 7514/6093/57120/5170/367/1432/11130/81929/5590/1072/5347/387/999/6232/332/1780/5579/3895/1499/8655/30849/5289/2316/695/140735/6279/10458/4771/5578/6714/5515/5580 32 Salivirus_A R-HSA-1234174 Cellular response to hypoxia 13/474 75/10654 2.294142176196543e-5 1.1174692535667031e-4 6.098423053871965e-5 7322/5716/7311/3091/1387/2034/7316/112399/7321/405/7428/7314/6233 13 Salivirus_A R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 13/474 75/10654 2.294142176196543e-5 1.1174692535667031e-4 6.098423053871965e-5 5295/8660/2064/1956/5290/2260/3667/2100/5291/2264/6714/5156/10818 13 Salivirus_A R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 14/474 86/10654 2.344503871253269e-5 1.1367617394104154e-4 6.203708939868622e-5 5295/3708/1072/5290/5581/3320/5291/695/10458/4771/6714/7525/3326/5580 14 Salivirus_A R-HSA-8878166 Transcriptional regulation by RUNX2 17/474 121/10654 2.3974532844092045e-5 1.1571269961737576e-4 6.314849314377526e-5 5716/8454/6500/7311/367/7291/1019/10000/7316/11059/207/10413/6714/208/7314/6233/7525 17 Salivirus_A R-HSA-844456 The NLRP3 inflammasome 6/474 15/10654 2.667930241032519e-5 1.2818192112597148e-4 6.995338622420194e-5 4210/29108/4790/5970/4791/3326 6 Salivirus_A R-HSA-190236 Signaling by FGFR 14/474 87/10654 2.6825153678828694e-5 1.2829949067204492e-4 7.00175480638158e-5 5295/7311/4670/4893/5290/2260/3845/7316/2264/6714/10818/7314/6233/5515 14 Salivirus_A R-HSA-186763 Downstream signal transduction 8/474 29/10654 2.7154956837178393e-5 1.2871205998608772e-4 7.024270166048507e-5 5295/4893/5290/3845/5291/6774/6714/5156 8 Salivirus_A R-HSA-5218920 VEGFR2 mediated vascular permeability 8/474 29/10654 2.7154956837178393e-5 1.2871205998608772e-4 7.024270166048507e-5 2475/5170/10000/3320/1499/207/208/253260 8 Salivirus_A R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 14/474 88/10654 3.062608098042133e-5 1.4451681962636317e-4 7.886791530672412e-5 5716/3315/7514/7311/3303/1432/7316/9261/207/5578/7314/6233/1994/5580 14 Salivirus_A R-HSA-2990846 SUMOylation 22/474 188/10654 3.100208629190062e-5 1.456409120468398e-4 7.948137210742242e-5 672/367/1387/81929/7155/8517/332/9641/6117/8243/9126/7022/5468/1029/7428/7157/5970/4792/6045/6790/5987/4791 22 Salivirus_A R-HSA-1250196 SHC1 events in ERBB2 signaling 7/474 22/10654 3.142810093357936e-5 1.4634142152772416e-4 7.986366478832129e-5 2064/4893/1956/5581/3845/5578/5580 7 Salivirus_A R-HSA-9613829 Chaperone Mediated Autophagy 7/474 22/10654 3.142810093357936e-5 1.4634142152772416e-4 7.986366478832129e-5 7311/3920/3320/7316/7314/6233/3326 7 Salivirus_A R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 10/474 47/10654 3.241723207253002e-5 1.476940271580355e-4 8.060182929104561e-5 8454/6500/7311/3091/1387/7316/2648/55869/7314/6233 10 Salivirus_A R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 10/474 47/10654 3.241723207253002e-5 1.476940271580355e-4 8.060182929104561e-5 5037/818/4893/4140/3845/369/8315/4296/5894/6714 10 Salivirus_A R-HSA-6802949 Signaling by RAS mutants 10/474 47/10654 3.241723207253002e-5 1.476940271580355e-4 8.060182929104561e-5 5037/818/4893/4140/3845/369/8315/4296/5894/6714 10 Salivirus_A R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 10/474 47/10654 3.241723207253002e-5 1.476940271580355e-4 8.060182929104561e-5 5037/818/4893/4140/3845/369/8315/4296/5894/6714 10 Salivirus_A R-HSA-9649948 Signaling downstream of RAS mutants 10/474 47/10654 3.241723207253002e-5 1.476940271580355e-4 8.060182929104561e-5 5037/818/4893/4140/3845/369/8315/4296/5894/6714 10 Salivirus_A R-HSA-3371556 Cellular response to heat stress 14/474 89/10654 3.489167638110362e-5 1.5828541602929842e-4 8.638192300359063e-5 2475/6119/818/3303/6118/1387/81929/3309/3320/6117/57521/9261/2288/3326 14 Salivirus_A R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 8/474 30/10654 3.560258157119919e-5 1.599856203985127e-4 8.730978437323604e-5 7311/6119/6118/1642/6117/7316/7314/6233 8 Salivirus_A R-HSA-418889 Caspase activation via Dependence Receptors in the absence of ligand 5/474 10/10654 3.572053586948817e-5 1.599856203985127e-4 8.730978437323604e-5 1613/23604/836/1612/842 5 Salivirus_A R-HSA-8853334 Signaling by FGFR3 fusions in cancer 5/474 10/10654 3.572053586948817e-5 1.599856203985127e-4 8.730978437323604e-5 5295/4893/5290/3845/10818 5 Salivirus_A R-HSA-73893 DNA Damage Bypass 10/474 48/10654 3.934330150867878e-5 1.754678046188754e-4 9.575895725852086e-5 7311/6119/6118/7706/1642/6117/7316/9100/7314/6233 10 Salivirus_A R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 9/474 39/10654 4.064612876969591e-5 1.8051663071247303e-4 9.85142793710454e-5 7311/6119/6118/7706/6117/7316/9100/7314/6233 9 Salivirus_A R-HSA-1295596 Spry regulation of FGF signaling 6/474 16/10654 4.1089726125186847e-5 1.8096600214301042e-4 9.875951717808067e-5 7311/7316/6714/7314/6233/5515 6 Salivirus_A R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 6/474 16/10654 4.1089726125186847e-5 1.8096600214301042e-4 9.875951717808067e-5 7311/5590/387/7316/7314/6233 6 Salivirus_A R-HSA-9006936 Signaling by TGF-beta family members 15/474 102/10654 4.175545581704914e-5 1.8313492447560558e-4 9.99431744387112e-5 7514/1030/7311/23327/23645/5590/387/1874/7316/23439/7321/4087/5499/7314/6233 15 Salivirus_A R-HSA-8951664 Neddylation 25/474 234/10654 4.3042625944237176e-5 1.8800022984735e-4 1.0259834283358842e-4 7322/5716/8454/6500/7311/3091/8945/2034/23291/8533/332/149951/1642/8452/8835/9903/7316/7321/10987/7428/50813/9817/7314/6233/51138 25 Salivirus_A R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 7/474 23/10654 4.3459175475695984e-5 1.8903847110210146e-4 1.031649476312818e-4 7311/23327/7316/7321/4087/7314/6233 7 Salivirus_A R-HSA-5654733 Negative regulation of FGFR4 signaling 8/474 31/10654 4.613791241132144e-5 1.9986792384740475e-4 1.0907496117948296e-4 7311/7316/2264/6714/10818/7314/6233/5515 8 Salivirus_A R-HSA-177929 Signaling by EGFR 10/474 49/10654 4.749476250711735e-5 2.0490597538784915e-4 1.1182440323909909e-4 5295/7311/4893/1956/5290/3845/7316/6714/7314/6233 10 Salivirus_A R-HSA-6783310 Fanconi Anemia Pathway 9/474 40/10654 5.0407602607733096e-5 2.1658876405030033e-4 1.1820011223379435e-4 7311/6119/6118/2189/6117/2175/7316/7314/6233 9 Salivirus_A R-HSA-438064 Post NMDA receptor activation events 13/474 81/10654 5.331581070240618e-5 2.2815713324875843e-4 1.2451337849954652e-4 51422/818/5170/5563/5571/5562/53632/4893/3845/6195/5564/5565/6714 13 Salivirus_A R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 7/474 24/10654 5.9021478606161704e-5 2.51086737063876e-4 1.370268703988488e-4 7514/596/1956/10000/2309/207/208 7 Salivirus_A R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 8/474 32/10654 5.914909889205782e-5 2.51086737063876e-4 1.370268703988488e-4 1030/7311/1874/7316/23439/4087/7314/6233 8 Salivirus_A R-HSA-9034015 Signaling by NTRK3 (TRKC) 6/474 17/10654 6.112821718538525e-5 2.584501022598088e-4 1.4104531796880473e-4 5295/4893/5290/3667/3845/6714 6 Salivirus_A R-HSA-4755510 SUMOylation of immune response proteins 5/474 11/10654 6.309649120962545e-5 2.6570912832101233e-4 1.4500682400031347e-4 8517/9641/5970/4792/4791 5 Salivirus_A R-HSA-69206 G1/S Transition 17/474 131/10654 6.738983164022125e-5 2.826629049353725e-4 1.5425909665347221e-4 5716/8454/6500/7311/6119/6118/1019/10000/6117/1874/7316/207/208/7314/6233/5515/7298 17 Salivirus_A R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 12/474 72/10654 7.043681698279632e-5 2.94275555536821e-4 1.60596528839494e-4 51422/8773/5563/5571/53632/5564/60412/5565/207/149371/208/55770 12 Salivirus_A R-HSA-5654726 Negative regulation of FGFR1 signaling 8/474 33/10654 7.507277246293932e-5 3.124091358004994e-4 1.7049266187190533e-4 7311/2260/7316/6714/10818/7314/6233/5515 8 Salivirus_A R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 7/474 25/10654 7.885963310160528e-5 3.268809105427325e-4 1.7839041873964786e-4 7311/6119/6118/6117/7316/7314/6233 7 Salivirus_A R-HSA-5654738 Signaling by FGFR2 12/474 73/10654 8.09574447606112e-5 3.342656996561173e-4 1.8242055809545617e-4 5295/7311/4670/4893/5290/3845/7316/6714/10818/7314/6233/5515 12 Salivirus_A R-HSA-111471 Apoptotic factor-mediated response 6/474 18/10654 8.826708830388397e-5 3.616213656480828e-4 1.9734950791729263e-4 836/331/1029/842/54205/578 6 Salivirus_A R-HSA-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 6/474 18/10654 8.826708830388397e-5 3.616213656480828e-4 1.9734950791729263e-4 330/329/7187/7186/958/9020 6 Salivirus_A R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 13/474 85/10654 8.921805521756594e-5 3.641061172392556e-4 1.9870552432117922e-4 5716/8454/6500/51343/7311/1019/10000/1874/7316/207/208/7314/6233 13 Salivirus_A R-HSA-69242 S Phase 19/474 161/10654 9.518061316024173e-5 3.869458004245212e-4 2.1116994336766183e-4 5716/8454/6500/51343/7311/6119/6118/1019/10000/6117/1874/8243/9126/7316/7321/207/208/7314/6233 19 Salivirus_A R-HSA-1660499 Synthesis of PIPs at the plasma membrane 10/474 53/10654 9.60595283240743e-5 3.890226875040097e-4 2.1230337375113017e-4 5295/146850/23533/5290/5294/5291/5728/5868/5286/5287 10 Salivirus_A R-HSA-3371511 HSF1 activation 5/474 12/10654 1.0422013607259564e-4 4.2046062530050993e-4 2.2946016298827808e-4 6119/6118/3320/6117/3326 5 Salivirus_A R-HSA-5696398 Nucleotide Excision Repair 15/474 111/10654 1.1269424425346213e-4 4.529194531403402e-4 2.4717408785630276e-4 7311/6119/6118/8533/1642/6117/7334/7316/10987/5886/50813/7314/10445/6233/51138 15 Salivirus_A R-HSA-9007101 Rab regulation of trafficking 16/474 124/10654 1.1751238486439111e-4 4.7049466212750534e-4 2.5676549802905235e-4 7249/8408/83696/11345/338382/10000/5868/9363/7248/81631/207/7879/11337/51256/208/9367 16 Salivirus_A R-HSA-204998 Cell death signalling via NRAGE, NRIF and NADE 12/474 76/10654 1.2102413607307194e-4 4.8272645973296995e-4 2.634408205284744e-4 7311/4804/836/5599/7316/4803/10018/572/7189/8878/7314/6233 12 Salivirus_A R-HSA-6804760 Regulation of TP53 Activity through Methylation 6/474 19/10654 1.2419054671502814e-4 4.934940145781381e-4 2.693170542138323e-4 7311/7316/7157/7314/6233/4194 6 Salivirus_A R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 11/474 66/10654 1.4052030789558196e-4 5.562920054143451e-4 3.0358812823488634e-4 7322/5716/7311/3091/2034/7316/112399/7321/7428/7314/6233 11 Salivirus_A R-HSA-6802952 Signaling by BRAF and RAF fusions 11/474 67/10654 1.6151251055757999e-4 6.370101629080673e-4 3.476388679715391e-4 4000/5037/818/10533/4893/4140/3845/10018/369/5894/6714 11 Salivirus_A R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 6/474 20/10654 1.7079839298849193e-4 6.711297449399107e-4 3.662591248589066e-4 7161/1387/7159/7157/665/8626 6 Salivirus_A R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 12/474 79/10654 1.7701782167298016e-4 6.929919907716298e-4 3.781901219368154e-4 7311/6119/6118/8533/1642/6117/7316/10987/50813/7314/6233/51138 12 Salivirus_A R-HSA-73894 DNA Repair 30/474 334/10654 1.9413943013951184e-4 7.572154157101992e-4 4.13239105521276e-4 672/7311/6119/6118/7013/5531/6047/9025/2189/25913/7706/8533/151987/1642/6117/2175/5599/5591/7334/7316/328/10987/7157/5886/50813/9100/7314/10445/6233/51138 30 Salivirus_A R-HSA-5654732 Negative regulation of FGFR3 signaling 7/474 29/10654 2.19351986385298e-4 8.492858960046153e-4 4.6348520739982e-4 7311/7316/6714/10818/7314/6233/5515 7 Salivirus_A R-HSA-9619483 Activation of AMPK downstream of NMDARs 7/474 29/10654 2.19351986385298e-4 8.492858960046153e-4 4.6348520739982e-4 51422/5563/5571/5562/53632/5564/5565 7 Salivirus_A R-HSA-442755 Activation of NMDA receptors and postsynaptic events 13/474 93/10654 2.267030522368594e-4 8.745442562567897e-4 4.7726958365654616e-4 51422/818/5170/5563/5571/5562/53632/4893/3845/6195/5564/5565/6714 13 Salivirus_A R-HSA-389513 CTLA4 inhibitory signaling 6/474 21/10654 2.302072532751235e-4 8.84832969861111e-4 4.828844968220773e-4 10000/207/6714/208/7525/5515 6 Salivirus_A R-HSA-400253 Circadian Clock 11/474 70/10654 2.4114745097474644e-4 9.235248394214021e-4 5.040000119533221e-4 8454/6500/7311/3091/8945/1387/1386/7316/5499/7314/6233 11 Salivirus_A R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 10/474 59/10654 2.4368676770168985e-4 9.298805540096974e-4 5.074685491184725e-4 7322/7311/5591/7334/7316/7321/79139/8915/7314/6233 10 Salivirus_A R-HSA-3371568 Attenuation phase 5/474 14/10654 2.4460751549122494e-4 9.300364887562041e-4 5.075536481983767e-4 3303/1387/3320/2288/3326 5 Salivirus_A R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 7/474 30/10654 2.7527571828524173e-4 0.0010428904452598584 5.691420246003112e-4 7322/7311/7316/7321/997/7314/6233 7 Salivirus_A R-HSA-5610780 Degradation of GLI1 by the proteasome 10/474 60/10654 2.810142375236614e-4 0.0010608287466518217 5.789315870788213e-4 5716/8454/6500/7311/8945/2735/7316/83737/7314/6233 10 Salivirus_A R-HSA-69202 Cyclin E associated events during G1/S transition 12/474 83/10654 2.849655968655131e-4 0.0010719168536898482 5.849827573789144e-4 5716/8454/6500/7311/1019/10000/1874/7316/207/208/7314/6233 12 Salivirus_A R-HSA-1483255 PI Metabolism 12/474 84/10654 3.1934321815981387e-4 0.001196970856719586 6.532291285986488e-4 5295/146850/23533/5290/5294/5291/5728/5868/30849/5286/5289/5287 12 Salivirus_A R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 7/474 31/10654 3.421075783318007e-4 0.0012777657607657715 6.973217516303767e-4 1432/3725/1386/5599/6195/9261/5515 7 Salivirus_A R-HSA-1980143 Signaling by NOTCH1 11/474 73/10654 3.5168311086911916e-4 0.0013089050992558414 7.143155847156313e-4 8454/6500/7311/3091/1387/7316/2648/55869/83737/7314/6233 11 Salivirus_A R-HSA-111447 Activation of BAD and translocation to mitochondria 5/474 15/10654 3.5357162203167466e-4 0.0013113165069736144 7.156315747861782e-4 596/10000/572/207/208 5 Salivirus_A R-HSA-9006931 Signaling by Nuclear Receptors 27/474 299/10654 3.697276233294753e-4 0.001366440901605788 7.45714897256358e-4 5295/3315/7514/5170/3725/1387/596/5590/1386/4893/1956/5290/10000/3320/3845/2100/2309/8243/9126/8202/8877/207/2288/2289/6714/208/3326 27 Salivirus_A R-HSA-5696400 Dual Incision in GG-NER 8/474 41/10654 3.777454086371179e-4 0.0013912087001025561 7.592315566959128e-4 7311/6119/6118/1642/6117/7316/7314/6233 8 Salivirus_A R-HSA-5693607 Processing of DNA double-strand break ends 13/474 98/10654 3.83444879077342e-4 0.0014072959624470503 7.680109420116353e-4 672/7311/6119/6118/5531/6047/9025/151987/6117/7334/7316/7314/6233 13 Salivirus_A R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 12/474 86/10654 3.987245991888828e-4 0.001453282418422928 7.931073697114621e-4 5716/8454/6500/51343/7311/8945/5347/7316/7321/6790/7314/6233 12 Salivirus_A R-HSA-453276 Regulation of mitotic cell cycle 12/474 86/10654 3.987245991888828e-4 0.001453282418422928 7.931073697114621e-4 5716/8454/6500/51343/7311/8945/5347/7316/7321/6790/7314/6233 12 Salivirus_A R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 12/474 88/10654 4.941669318898628e-4 0.0017949637354212542 9.795748912123162e-4 8454/6500/7311/8945/5347/23291/3320/7316/8655/6790/7314/6233 12 Salivirus_A R-HSA-1433557 Signaling by SCF-KIT 8/474 43/10654 5.30234341242998e-4 0.0019193756804583868 0.0010474708687857352 5295/4893/5290/3845/6774/5578/6714/7525 8 Salivirus_A R-HSA-5687128 MAPK6/MAPK4 signaling 12/474 89/10654 5.486782514070547e-4 0.001979361473505996 0.0010802072274872139 5716/3315/7514/2308/7311/3725/2309/7316/8202/5597/7314/6233 12 Salivirus_A R-HSA-913531 Interferon Signaling 20/474 199/10654 5.519626265176055e-4 0.0019844370620037723 0.0010829771547857063 7311/818/23586/81929/5610/11274/6737/7706/3115/7334/7316/10410/3661/2316/4734/5495/51191/7314/6233/5580 20 Salivirus_A R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 9/474 54/10654 5.637483212000711e-4 0.0020199389000287293 0.0011023517574224406 7311/8533/1642/7316/10987/50813/7314/6233/51138 9 Salivirus_A R-HSA-5654727 Negative regulation of FGFR2 signaling 7/474 34/10654 6.234920162924613e-4 0.0022264562879092285 0.0012150555651787654 7311/7316/6714/10818/7314/6233/5515 7 Salivirus_A R-HSA-68882 Mitotic Anaphase 20/474 201/10654 6.273125117016202e-4 0.0022325566493892677 0.0012183847471645862 5716/4000/7514/7311/11130/81929/5347/6232/332/1780/8243/9126/7316/55869/7321/8655/140735/7314/6233/5515 20 Salivirus_A R-HSA-76002 Platelet activation, signaling and aggregation 24/474 262/10654 6.305574383489858e-4 0.0022365745380365032 0.0012205774504247412 5295/5170/146850/1432/3920/3708/5590/23533/1072/387/5588/5290/5581/3309/5294/5579/5291/308/2316/5894/207/5578/6714/5580 24 Salivirus_A R-HSA-2029485 Role of phospholipids in phagocytosis 6/474 25/10654 6.456481114605148e-4 0.002268059323569606 0.001237759806120743 5295/3708/5290/5581/5291/5580 6 Salivirus_A R-HSA-9006115 Signaling by NTRK2 (TRKB) 6/474 25/10654 6.456481114605148e-4 0.002268059323569606 0.001237759806120743 5295/4893/5290/3845/6714/10818 6 Salivirus_A R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 9/474 55/10654 6.480169495913159e-4 0.002268059323569606 0.001237759806120743 5716/8454/6500/51343/7311/8945/7316/7314/6233 9 Salivirus_A R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 9/474 55/10654 6.480169495913159e-4 0.002268059323569606 0.001237759806120743 3303/367/3320/1780/8655/140735/2288/2289/3326 9 Salivirus_A R-HSA-450341 Activation of the AP-1 family of transcription factors 4/474 10/10654 6.55698554253363e-4 0.002279846617913831 0.00124419254754447 1432/3725/1386/5599 4 Salivirus_A R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 4/474 10/10654 6.55698554253363e-4 0.002279846617913831 0.00124419254754447 2308/1387/2309/4303 4 Salivirus_A R-HSA-2555396 Mitotic Metaphase and Anaphase 20/474 202/10654 6.682160267505253e-4 0.0023157519353288695 0.0012637873430864123 5716/4000/7514/7311/11130/81929/5347/6232/332/1780/8243/9126/7316/55869/7321/8655/140735/7314/6233/5515 20 Salivirus_A R-HSA-6806834 Signaling by MET 11/474 79/10654 7.026312783838631e-4 0.0024191572027744083 0.0013202192372856402 5295/7311/4893/5290/3845/7316/6774/6714/7314/6233/3910 11 Salivirus_A R-HSA-8852135 Protein ubiquitination 11/474 79/10654 7.026312783838631e-4 0.0024191572027744083 0.0013202192372856402 7322/7311/5591/7334/7316/7321/79139/997/8915/7314/6233 11 Salivirus_A R-HSA-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle 7/474 35/10654 7.499492526759394e-4 0.0025736894807742465 0.0014045529407601327 7311/51009/7316/79139/7314/6233/821 7 Salivirus_A R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 11/474 80/10654 7.827560408011948e-4 0.002677582961575608 0.0014612512701722188 5716/8454/6500/51343/7311/8945/5347/7316/7321/7314/6233 11 Salivirus_A R-HSA-2467813 Separation of Sister Chromatids 19/474 190/10654 8.008657032061441e-4 0.0027306937041577236 0.0014902356718402955 5716/7514/7311/11130/81929/5347/6232/332/1780/8243/9126/7316/55869/7321/8655/140735/7314/6233/5515 19 Salivirus_A R-HSA-901042 Calnexin/calreticulin cycle 6/474 26/10654 8.081978638907993e-4 0.002746833254445578 0.001499043592527189 7311/51009/7316/7314/6233/821 6 Salivirus_A R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 7/474 36/10654 8.958581317891023e-4 0.003035006555452183 0.001656309906276748 5037/4893/4140/3845/369/5894/6714 7 Salivirus_A R-HSA-210993 Tie2 Signaling 5/474 18/10654 9.029406568773037e-4 0.0030395167971952546 0.0016587713039516007 5295/4893/5290/3845/5291 5 Salivirus_A R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 5/474 18/10654 9.029406568773037e-4 0.0030395167971952546 0.0016587713039516007 4893/1956/3845/6195/5578 5 Salivirus_A R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 9/474 58/10654 9.644532024816982e-4 0.0031956960345553447 0.0017440038111201804 8454/6500/7311/1387/7316/2648/55869/7314/6233 9 Salivirus_A R-HSA-2644603 Signaling by NOTCH1 in Cancer 9/474 58/10654 9.644532024816982e-4 0.0031956960345553447 0.0017440038111201804 8454/6500/7311/1387/7316/2648/55869/7314/6233 9 Salivirus_A R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 9/474 58/10654 9.644532024816982e-4 0.0031956960345553447 0.0017440038111201804 8454/6500/7311/1387/7316/2648/55869/7314/6233 9 Salivirus_A R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 9/474 58/10654 9.644532024816982e-4 0.0031956960345553447 0.0017440038111201804 8454/6500/7311/1387/7316/2648/55869/7314/6233 9 Salivirus_A R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 9/474 58/10654 9.644532024816982e-4 0.0031956960345553447 0.0017440038111201804 8454/6500/7311/1387/7316/2648/55869/7314/6233 9 Salivirus_A R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 4/474 11/10654 9.943283045640706e-4 0.0032639907388951014 0.001781274635178525 3091/1387/2034/405 4 Salivirus_A R-HSA-193692 Regulated proteolysis of p75NTR 4/474 11/10654 9.943283045640706e-4 0.0032639907388951014 0.001781274635178525 4804/4790/5970/7189 4 Salivirus_A R-HSA-351906 Apoptotic cleavage of cell adhesion proteins 4/474 11/10654 9.943283045640706e-4 0.0032639907388951014 0.001781274635178525 999/836/1499/7082 4 Salivirus_A R-HSA-5654716 Downstream signaling of activated FGFR4 6/474 27/10654 0.0010005878785958099 0.00326426354220917 0.0017814235135493954 5295/4893/5290/3845/2264/10818 6 Salivirus_A R-HSA-912526 Interleukin receptor SHC signaling 6/474 27/10654 0.0010005878785958099 0.00326426354220917 0.0017814235135493954 5295/1438/5290/1437/5291/1439 6 Salivirus_A R-HSA-202733 Cell surface interactions at the vascular wall 15/474 137/10654 0.0011172228757773395 0.0036335525529127624 0.0019829575252663387 5295/4893/5290/3845/482/5291/8795/481/2994/483/5669/6714/4099/7525/8797 15 Salivirus_A R-HSA-5655302 Signaling by FGFR1 in disease 7/474 38/10654 0.0012542479472163561 0.004066687362600271 0.002219334436792261 5295/4893/5290/2260/3845/6774/10818 7 Salivirus_A R-HSA-69620 Cell Cycle Checkpoints 25/474 293/10654 0.001363338924452285 0.004406878419406928 0.0024049886708509653 5716/672/7514/7311/6119/6118/9025/11130/81929/5347/6232/332/1780/6117/7334/7316/1029/7321/8655/7157/140735/7314/6233/5515/4194 25 Salivirus_A R-HSA-8943724 Regulation of PTEN gene transcription 9/474 61/10654 0.0013960042608517208 0.004498708852805698 0.0024551037706891624 2475/3725/1386/5468/6009/1822/7157/57521/6045 9 Salivirus_A R-HSA-430116 GP1b-IX-V activation signalling 4/474 12/10654 0.0014393823888098115 0.004610385409005972 0.0025160495983023185 5295/2316/5894/6714 4 Salivirus_A R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 4/474 12/10654 0.0014393823888098115 0.004610385409005972 0.0025160495983023185 7161/843/7157/8626 4 Salivirus_A R-HSA-162588 Budding and maturation of HIV virion 6/474 29/10654 0.0014889879937290903 0.004740543100517014 0.0025870812319706456 7311/23327/7316/51534/7314/6233 6 Salivirus_A R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 6/474 29/10654 0.0014889879937290903 0.004740543100517014 0.0025870812319706456 2308/4287/2309/3630/4087/4303 6 Semliki_forest_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 13/72 182/10654 2.0221509548176759e-10 1.0138340692098372e-7 5.51941763742591e-8 6045/8021/9883/2099/9972/4927/3066/7157/4792/4193/23512/648/23636 13 Semliki_forest_virus R-HSA-2990846 SUMOylation 13/72 188/10654 3.030894078355268e-10 1.0138340692098372e-7 5.51941763742591e-8 6045/8021/9883/2099/9972/4927/3066/7157/4792/4193/23512/648/23636 13 Semliki_forest_virus R-HSA-4551638 SUMOylation of chromatin organization proteins 9/72 71/10654 9.368700784887713e-10 2.08922027502996e-7 1.1373931479197014e-7 6045/8021/9883/9972/4927/3066/23512/648/23636 9 Semliki_forest_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 9/72 80/10654 2.780104674873094e-9 4.64972506872525e-7 2.531358467121291e-7 7316/7706/5300/8021/9883/9972/4927/4940/23636 9 Semliki_forest_virus R-HSA-5688426 Deubiquitination 14/72 297/10654 8.80659292466342e-9 1.1783221333199658e-6 6.414907688281145e-7 7316/5728/1540/409/7706/5698/2099/9100/9097/7157/7415/4792/51720/4193 14 Semliki_forest_virus R-HSA-1257604 PIP3 activates AKT signaling 13/72 264/10654 1.9044362839426957e-8 2.0702094809143426e-6 1.1270434747798955e-6 5295/7316/5728/6045/5698/2099/3066/5978/7157/4193/11060/23512/648 13 Semliki_forest_virus R-HSA-4570464 SUMOylation of RNA binding proteins 7/72 47/10654 2.42372828689399e-8 2.0702094809143426e-6 1.1270434747798955e-6 6045/8021/9883/9972/4927/648/23636 7 Semliki_forest_virus R-HSA-1169408 ISG15 antiviral mechanism 8/72 72/10654 2.4755868232159552e-8 2.0702094809143426e-6 1.1270434747798955e-6 7316/7706/5300/8021/9883/9972/4927/23636 8 Semliki_forest_virus R-HSA-6807070 PTEN Regulation 10/72 140/10654 2.9780098167077097e-8 2.2136539637527307e-6 1.205136136351892e-6 7316/5728/6045/5698/3066/5978/7157/11060/23512/648 10 Semliki_forest_virus R-HSA-913531 Interferon Signaling 11/72 199/10654 8.18651775193839e-8 5.290238326784615e-6 2.8800605161945983e-6 10437/7316/7706/5300/8021/9883/9972/9830/4927/4940/23636 11 Semliki_forest_virus R-HSA-2262752 Cellular responses to stress 16/72 479/10654 8.698448668853627e-8 5.290238326784615e-6 2.8800605161945983e-6 7316/6045/1017/8021/7014/9883/5698/9972/768/4927/7157/7415/4193/23512/648/23636 16 Semliki_forest_virus R-HSA-9006925 Intracellular signaling by second messengers 13/72 305/10654 1.0452102520060133e-7 5.827047154933524e-6 3.1723047999480753e-6 5295/7316/5728/6045/5698/2099/3066/5978/7157/4193/11060/23512/648 13 Semliki_forest_virus R-HSA-8953897 Cellular responses to external stimuli 16/72 493/10654 1.2929445469888207e-7 6.653691553350161e-6 3.6223385688917573e-6 7316/6045/1017/8021/7014/9883/5698/9972/768/4927/7157/7415/4193/23512/648/23636 16 Semliki_forest_virus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 6/72 38/10654 1.793397421866839e-7 7.998552501526103e-6 4.3544947927433436e-6 8021/9883/9972/4927/4193/23636 6 Semliki_forest_virus R-HSA-5689896 Ovarian tumor domain proteases 6/72 38/10654 1.793397421866839e-7 7.998552501526103e-6 4.3544947927433436e-6 7316/5728/7706/2099/7157/7415 6 Semliki_forest_virus R-HSA-168273 Influenza Viral RNA Transcription and Replication 9/72 134/10654 2.618895250423355e-7 1.0950255765832653e-5 5.961432609516322e-6 8021/6194/200916/9883/6134/9972/4927/6123/23636 9 Semliki_forest_virus R-HSA-168255 Influenza Life Cycle 9/72 144/10654 4.837369075616823e-7 1.9036470068162674e-5 1.0363651394200751e-5 8021/6194/200916/9883/6134/9972/4927/6123/23636 9 Semliki_forest_virus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 11/72 244/10654 6.396160970290241e-7 2.377239827291206e-5 1.294193974105511e-5 6625/22938/8021/3178/9883/9972/9343/4927/1994/23636/10594 11 Semliki_forest_virus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 7/72 77/10654 7.892333239501328e-7 2.778932072224415e-5 1.5128793910623045e-5 6045/8021/9883/9972/4927/648/23636 7 Semliki_forest_virus R-HSA-168254 Influenza Infection 9/72 155/10654 9.010139218269199e-7 3.013891568511047e-5 1.6407937734321804e-5 8021/6194/200916/9883/6134/9972/4927/6123/23636 9 Semliki_forest_virus R-HSA-5663202 Diseases of signal transduction 13/72 377/10654 1.183028595774362e-6 3.768791097966896e-5 2.0517688929219513e-5 5295/7316/5728/8454/22938/409/5245/5698/2099/3066/3845/7415/4193 13 Semliki_forest_virus R-HSA-191859 snRNP Assembly 6/72 53/10654 1.376973101568905e-6 4.005195673693902e-5 2.1804699915004175e-5 8021/9883/9972/4927/79084/23636 6 Semliki_forest_virus R-HSA-194441 Metabolism of non-coding RNA 6/72 53/10654 1.376973101568905e-6 4.005195673693902e-5 2.1804699915004175e-5 8021/9883/9972/4927/79084/23636 6 Semliki_forest_virus R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 5/72 31/10654 1.8147111646839903e-6 4.496450996939221e-5 2.4479144755581315e-5 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 5/72 31/10654 1.8147111646839903e-6 4.496450996939221e-5 2.4479144755581315e-5 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 5/72 31/10654 1.8147111646839903e-6 4.496450996939221e-5 2.4479144755581315e-5 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 5/72 31/10654 1.8147111646839903e-6 4.496450996939221e-5 2.4479144755581315e-5 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-5689880 Ub-specific processing proteases 10/72 220/10654 2.013426966458889e-6 4.810652287717845e-5 2.618968911258555e-5 7316/5728/1540/409/5698/9100/9097/7157/4792/4193 10 Semliki_forest_virus R-HSA-162909 Host Interactions of HIV factors 8/72 129/10654 2.3220193562378963e-6 5.2440710945995244e-5 2.8549265970127223e-5 7316/1025/8021/9883/5698/9972/4927/23636 8 Semliki_forest_virus R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 5/72 33/10654 2.5083748135603106e-6 5.2440710945995244e-5 2.8549265970127223e-5 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-180746 Nuclear import of Rev protein 5/72 33/10654 2.5083748135603106e-6 5.2440710945995244e-5 2.8549265970127223e-5 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-180910 Vpr-mediated nuclear import of PICs 5/72 33/10654 2.5083748135603106e-6 5.2440710945995244e-5 2.8549265970127223e-5 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-159227 Transport of the SLBP independent Mature mRNA 5/72 34/10654 2.9254656947706908e-6 5.591818713718834e-5 3.0442440011749148e-5 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-165054 Rev-mediated nuclear export of HIV RNA 5/72 34/10654 2.9254656947706908e-6 5.591818713718834e-5 3.0442440011749148e-5 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-4085377 SUMOylation of SUMOylation proteins 5/72 34/10654 2.9254656947706908e-6 5.591818713718834e-5 3.0442440011749148e-5 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-8943724 Regulation of PTEN gene transcription 6/72 61/10654 3.191651763366344e-6 5.931152860255789e-5 3.228981023756594e-5 6045/3066/5978/7157/23512/648 6 Semliki_forest_virus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 5/72 35/10654 3.395186480583782e-6 5.977315146080395e-5 3.2541122500886116e-5 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 5/72 35/10654 3.395186480583782e-6 5.977315146080395e-5 3.2541122500886116e-5 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-176033 Interactions of Vpr with host cellular proteins 5/72 36/10654 3.9221703124143975e-6 6.55982984751308e-5 3.571239284461531e-5 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-177243 Interactions of Rev with host cellular proteins 5/72 36/10654 3.9221703124143975e-6 6.55982984751308e-5 3.571239284461531e-5 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-168276 NS1 Mediated Effects on Host Pathways 5/72 40/10654 6.703710924673624e-6 1.0938494167333304e-4 5.9550294735226545e-5 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 5/72 41/10654 7.594855653526695e-6 1.2097520076688951e-4 6.586015178246208e-5 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-5663205 Infectious disease 12/72 383/10654 8.566181290139914e-6 1.2749811440288013e-4 6.941129349916847e-5 7316/1025/8021/6194/200916/9883/6134/5698/9972/4927/6123/23636 12 Semliki_forest_virus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 5/72 42/10654 8.576106349969515e-6 1.2749811440288013e-4 6.941129349916847e-5 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-168253 Host Interactions with Influenza Factors 5/72 42/10654 8.576106349969515e-6 1.2749811440288013e-4 6.941129349916847e-5 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-5654738 Signaling by FGFR2 6/72 73/10654 9.180279245854901e-6 1.335131916408028e-4 7.268596382301595e-5 5295/7316/7073/7072/3178/3845 6 Semliki_forest_virus R-HSA-168325 Viral Messenger RNA Synthesis 5/72 43/10654 9.653799232276427e-6 1.3741258907218999e-4 7.480883615605026e-5 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-4615885 SUMOylation of DNA replication proteins 5/72 45/10654 1.2125115462752456e-5 1.6899379676211236e-4 9.200197259018312e-5 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-5619115 Disorders of transmembrane transporters 8/72 176/10654 2.300126210646716e-5 3.140376397801333e-4 1.7096534240252715e-4 7316/8021/9883/5698/9972/4927/7415/23636 8 Semliki_forest_virus R-HSA-2980766 Nuclear Envelope Breakdown 5/72 52/10654 2.4863955537267863e-5 3.316221999321884e-4 1.80538559006431e-4 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-190236 Signaling by FGFR 6/72 87/10654 2.5280616138328263e-5 3.316221999321884e-4 1.80538559006431e-4 5295/7316/7073/7072/3178/3845 6 Semliki_forest_virus R-HSA-3371556 Cellular response to heat stress 6/72 89/10654 2.878423624142748e-5 3.7032027010605736e-4 2.016061890593909e-4 8021/9883/9972/4927/7415/23636 6 Semliki_forest_virus R-HSA-6784531 tRNA processing in the nucleus 5/72 57/10654 3.902219595946023e-5 4.925631905071489e-4 2.681565005357148e-4 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-162599 Late Phase of HIV Life Cycle 7/72 139/10654 4.018119840919684e-5 4.978004025139387e-4 2.710076929743101e-4 7316/1025/8021/9883/9972/4927/23636 7 Semliki_forest_virus R-HSA-8878159 Transcriptional regulation by RUNX3 6/72 96/10654 4.424418262716257e-5 5.381701486831229e-4 2.9298540074637803e-4 7316/22938/5698/3845/7157/4193 6 Semliki_forest_virus R-HSA-2559583 Cellular Senescence 8/72 195/10654 4.7924185942151024e-5 5.725228642017684e-4 3.1168737473654615e-4 7316/6045/1017/7014/7157/4193/23512/648 8 Semliki_forest_virus R-HSA-202424 Downstream TCR signaling 6/72 98/10654 4.970646258531109e-5 5.83396902974967e-4 3.176073140261798e-4 5295/7316/5728/8454/5698/4792 6 Semliki_forest_virus R-HSA-162587 HIV Life Cycle 7/72 152/10654 7.102451933319235e-5 8.19231093688029e-4 4.4599788909772335e-4 7316/1025/8021/9883/9972/4927/23636 7 Semliki_forest_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 4/72 34/10654 7.628480018499084e-5 8.514235205758564e-4 4.6352377959129313e-4 7316/1540/7706/5300 4 Semliki_forest_virus R-HSA-73894 DNA Repair 10/72 334/10654 7.636085386330551e-5 8.514235205758564e-4 4.6352377959129313e-4 7316/10973/7706/1017/7014/10987/9100/7157/7415/51720 10 Semliki_forest_virus R-HSA-69563 p53-Dependent G1 DNA Damage Response 5/72 66/10654 7.945597980546619e-5 8.573556530622078e-4 4.667532939336385e-4 7316/1017/5698/7157/4193 5 Semliki_forest_virus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 5/72 66/10654 7.945597980546619e-5 8.573556530622078e-4 4.667532939336385e-4 7316/1017/5698/7157/4193 5 Semliki_forest_virus R-HSA-69615 G1/S DNA Damage Checkpoints 5/72 68/10654 9.171357196320496e-5 9.73910787990224e-4 5.302071161114272e-4 7316/1017/5698/7157/4193 5 Semliki_forest_virus R-HSA-6804757 Regulation of TP53 Degradation 4/72 36/10654 9.591087929550901e-5 0.0010025684101358677 5.458086223066797e-4 7316/1017/7157/4193 4 Semliki_forest_virus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 5/72 69/10654 9.836277764062437e-5 0.0010123799729473493 5.511501386826887e-4 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 6/72 112/10654 1.0488301666019976e-4 0.0010631323961465702 5.787802833242284e-4 5295/7316/8454/5698/3845/4792 6 Semliki_forest_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 4/72 37/10654 1.0698961785577724e-4 0.0010682993185897756 5.81593209396684e-4 7316/1017/7157/4193 4 Semliki_forest_virus R-HSA-70171 Glycolysis 5/72 71/10654 1.1276818118208179e-4 0.0011094399001590105 6.039905679411812e-4 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-1980143 Signaling by NOTCH1 5/72 73/10654 1.2874064614934225e-4 0.00124822452570884 6.795463549606777e-4 7316/8454/22938/409/3066 5 Semliki_forest_virus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 4/72 39/10654 1.318911982311688e-4 0.0012605030230950277 6.862308960599161e-4 7316/7706/9100/7415 4 Semliki_forest_virus R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 5/72 75/10654 1.4639282143520874e-4 0.0013620037855555326 7.414889620049003e-4 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-202403 TCR signaling 6/72 119/10654 1.4658336705530397e-4 0.0013620037855555326 7.414889620049003e-4 5295/7316/5728/8454/5698/4792 6 Semliki_forest_virus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 7/72 171/10654 1.4866239535069064e-4 0.0013623992121864663 7.417042363567263e-4 7316/6194/200916/6134/5698/26986/6123 7 Semliki_forest_virus R-HSA-162906 HIV Infection 8/72 233/10654 1.6632410154638892e-4 0.0015036597828991106 8.186079535569071e-4 7316/1025/8021/9883/5698/9972/4927/23636 8 Semliki_forest_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 5/72 78/10654 1.7627625991037757e-4 0.001552582904465049 8.452422074500936e-4 7316/1540/7706/5300/4792 5 Semliki_forest_virus R-HSA-157118 Signaling by NOTCH 8/72 235/10654 1.763771311499906e-4 0.001552582904465049 8.452422074500936e-4 7316/8454/22938/409/5698/3066/7157/11060 8 Semliki_forest_virus R-HSA-2559580 Oxidative Stress Induced Senescence 6/72 125/10654 1.919342293712632e-4 0.0016675844084334426 9.078502168483537e-4 7316/6045/7157/4193/23512/648 6 Semliki_forest_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 5/72 83/10654 2.3618263360879646e-4 0.0020257202805677543 0.0011028230935039621 7316/8454/5698/3845/4792 5 Semliki_forest_virus R-HSA-72202 Transport of Mature Transcript to Cytoplasm 5/72 84/10654 2.4982227035303507e-4 0.0021155835299516514 0.001151745576844106 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 3/72 19/10654 2.6534883947161087e-4 0.0021648582147135082 0.0011785712253809676 5295/7316/3845 3 Semliki_forest_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 3/72 19/10654 2.6534883947161087e-4 0.0021648582147135082 0.0011785712253809676 5295/7316/3845 3 Semliki_forest_virus R-HSA-6804760 Regulation of TP53 Activity through Methylation 3/72 19/10654 2.6534883947161087e-4 0.0021648582147135082 0.0011785712253809676 7316/7157/4193 3 Semliki_forest_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 4/72 47/10654 2.7459278772309746e-4 0.0022132840359849666 0.001204934743845171 7316/8454/22938/3066 4 Semliki_forest_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 6/72 134/10654 2.800279676487605e-4 0.0022302227423454855 0.001214156350958285 5295/7316/8454/5698/3845/4792 6 Semliki_forest_virus R-HSA-73893 DNA Damage Bypass 4/72 48/10654 2.980350093589948e-4 0.0023457108383666764 0.001277029266107891 7316/7706/9100/7415 4 Semliki_forest_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 5/72 88/10654 3.104627406329255e-4 0.0024151113195747345 0.0013148116065972123 7316/8021/5698/26986/1994 5 Semliki_forest_virus R-HSA-70326 Glucose metabolism 5/72 91/10654 3.6281341842756085e-4 0.002789910079632623 0.0015188559319532495 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 5/72 92/10654 3.816669241532504e-4 0.002901536048392324 0.00157962626503618 7316/1017/5300/7157/4193 5 Semliki_forest_virus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 5/72 95/10654 4.4269314768048966e-4 0.0033276597280701976 0.001811612408012412 6194/200916/6134/26986/6123 5 Semliki_forest_virus R-HSA-5358351 Signaling by Hedgehog 6/72 149/10654 4.945367876457802e-4 0.0036760567881669657 0.002001283374566549 7316/8454/409/5698/8452/7415 6 Semliki_forest_virus R-HSA-5619102 SLC transporter disorders 5/72 99/10654 5.351825853877673e-4 0.003934474171696883 0.002141968473616744 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-69541 Stabilization of p53 4/72 57/10654 5.779610947594388e-4 0.004173656664993969 0.0022721818992808016 7316/5698/7157/4193 4 Semliki_forest_virus R-HSA-1643713 Signaling by EGFR in Cancer 3/72 25/10654 6.117721207801355e-4 0.004173656664993969 0.0022721818992808016 5295/7316/3845 3 Semliki_forest_virus R-HSA-1236394 Signaling by ERBB4 4/72 58/10654 6.176263226224259e-4 0.004173656664993969 0.0022721818992808016 5295/7316/2099/3845 4 Semliki_forest_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 4/72 58/10654 6.176263226224259e-4 0.004173656664993969 0.0022721818992808016 7316/8454/22938/3066 4 Semliki_forest_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 4/72 58/10654 6.176263226224259e-4 0.004173656664993969 0.0022721818992808016 7316/8454/22938/3066 4 Semliki_forest_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 4/72 58/10654 6.176263226224259e-4 0.004173656664993969 0.0022721818992808016 7316/8454/22938/3066 4 Semliki_forest_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 4/72 58/10654 6.176263226224259e-4 0.004173656664993969 0.0022721818992808016 7316/8454/22938/3066 4 Semliki_forest_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 4/72 58/10654 6.176263226224259e-4 0.004173656664993969 0.0022721818992808016 7316/8454/22938/3066 4 Semliki_forest_virus R-HSA-376176 Signaling by ROBO receptors 7/72 218/10654 6.502992533522864e-4 0.004350502004926797 0.0023684583332620117 7316/6194/200916/6134/5698/26986/6123 7 Semliki_forest_virus R-HSA-6803529 FGFR2 alternative splicing 3/72 26/10654 6.882272398807345e-4 0.004558653697823875 0.0024817782699190637 7073/7072/3178 3 Semliki_forest_virus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 4/72 60/10654 7.026924385787973e-4 0.004608835700090347 0.0025090978714991117 7316/8454/1017/5698 4 Semliki_forest_virus R-HSA-5633007 Regulation of TP53 Activity 6/72 160/10654 7.204186721654947e-4 0.004679224191055495 0.0025474180947292918 7316/1017/5300/3066/7157/4193 6 Semliki_forest_virus R-HSA-5578749 Transcriptional regulation by small RNAs 5/72 106/10654 7.31112540691206e-4 0.0047030220165617 0.002560373877319406 8021/9883/9972/4927/23636 5 Semliki_forest_virus R-HSA-3700989 Transcriptional Regulation by TP53 9/72 365/10654 7.448644488632052e-4 0.004745850631328421 0.0025836902186132235 7316/5728/1025/1017/2810/5300/3066/7157/4193 9 Semliki_forest_virus R-HSA-72306 tRNA processing 5/72 107/10654 7.629631594350473e-4 0.004815305223226854 0.0026215020175226053 8021/9883/9972/4927/23636 5 Sendai_virus R-HSA-3371556 Cellular response to heat stress 64/603 89/10654 1.3209936893619964e-60 1.430636165579042e-57 9.608490940517258e-58 2475/3306/27000/10049/23165/3303/9883/9972/348995/2932/1410/10013/6782/545/79023/57122/23636/3281/5903/259217/23225/23411/3310/3337/8021/573/9529/3313/10808/3309/3320/10762/55706/7175/129401/23511/7266/9631/3304/3312/1915/6767/3305/53371/116835/9531/3297/57521/55746/8086/9532/2288/22824/8480/10728/23279/4927/9688/9530/3308/51182/7415/3326/79902 64 Sendai_virus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 53/603 69/10654 7.091025950170389e-53 3.839790552017266e-50 2.5788941745093364e-50 3306/27000/10049/23165/3303/9883/9972/348995/2932/6782/545/79023/57122/23636/5903/259217/23225/23411/3310/3337/8021/573/9529/3313/10808/3309/10762/55706/7175/129401/23511/7266/9631/3304/3312/6767/3305/53371/116835/9531/3297/55746/8086/9532/22824/8480/23279/4927/9688/9530/3308/51182/79902 53 Sendai_virus R-HSA-913531 Interferon Signaling 83/603 199/10654 9.931951939248041e-52 3.585434650068543e-49 2.4080627333404903e-49 6041/3135/23165/3665/25939/1958/9883/9972/4939/348995/3133/9636/79023/2537/3429/57122/23636/5610/11274/8638/5903/10581/23225/7706/51447/3134/10379/2634/8021/10762/4940/3662/55706/7175/91543/3437/129401/23511/9631/3440/3394/3456/53371/6773/3458/4938/3454/3107/3663/8519/3664/10410/3430/55746/3105/3661/3669/103/8086/2633/5696/3836/9246/3660/3434/6672/85363/54739/8480/6772/51191/23279/4927/9688/3433/3659/4600/4599/3106/5580/684/79902/23586 83 Sendai_virus R-HSA-909733 Interferon alpha/beta signaling 48/603 69/10654 1.9807975914544398e-44 5.363009478862896e-42 3.601924041302679e-42 6041/3135/3665/25939/1958/4939/3133/9636/2537/3429/11274/8638/10581/51447/3134/10379/2634/4940/3662/91543/3437/3440/3394/3456/6773/4938/3454/3107/3663/8519/3664/10410/3430/3105/3661/3669/103/5696/3660/3434/54739/6772/3433/3659/4600/4599/3106/684 48 Sendai_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 49/603 78/10654 5.316430407920056e-42 1.1515388263554841e-39 7.734007182890018e-40 7322/1147/3665/55593/84282/9636/54476/79671/5094/7187/351/843/841/7706/8517/8772/84166/9641/7186/4790/80143/7323/9474/64135/3440/1540/3551/3456/7321/54941/8737/5970/4792/83737/3661/9140/4793/9246/4791/29110/7189/6285/57506/51191/79132/10010/3093/4214/23586 49 Sendai_virus R-HSA-2262752 Cellular responses to stress 111/603 479/10654 4.7052402089897395e-40 8.49295857722648e-38 5.704071902477035e-38 2475/7322/5716/55004/3306/27000/10049/7295/2353/10294/1017/23165/3303/7014/5598/3091/830/9883/7013/367/9972/348995/2932/5701/1410/10013/6782/5688/545/4683/79023/57122/23636/2034/79400/3281/5684/5903/259217/23225/23411/3310/3337/2908/8021/573/9529/3313/10808/3309/4343/3320/10762/4790/55706/7175/5599/847/129401/23511/7323/7266/9631/3304/9978/3312/112399/1029/4217/1915/3456/5710/6767/10935/3305/53371/116835/7321/3301/7428/527/54386/9531/7157/3297/5970/57521/55746/8086/55466/9532/54205/5696/2288/10963/22824/7422/2289/8480/10728/23279/4927/9688/9530/3308/51182/7415/4193/6647/3326/79902 111 Sendai_virus R-HSA-8953897 Cellular responses to external stimuli 111/603 493/10654 8.89688338355539e-39 1.3764749577700696e-36 9.244731455694397e-37 2475/7322/5716/55004/3306/27000/10049/7295/2353/10294/1017/23165/3303/7014/5598/3091/830/9883/7013/367/9972/348995/2932/5701/1410/10013/6782/5688/545/4683/79023/57122/23636/2034/79400/3281/5684/5903/259217/23225/23411/3310/3337/2908/8021/573/9529/3313/10808/3309/4343/3320/10762/4790/55706/7175/5599/847/129401/23511/7323/7266/9631/3304/9978/3312/112399/1029/4217/1915/3456/5710/6767/10935/3305/53371/116835/7321/3301/7428/527/54386/9531/7157/3297/5970/57521/55746/8086/55466/9532/54205/5696/2288/10963/22824/7422/2289/8480/10728/23279/4927/9688/9530/3308/51182/7415/4193/6647/3326/79902 111 Sendai_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 42/603 80/10654 1.3510069447010926e-31 1.828925651389104e-29 1.2283497352479672e-29 6041/23165/9883/9972/4939/348995/9636/79023/57122/23636/5610/11274/8638/5903/23225/7706/8021/10762/4940/55706/7175/129401/23511/9631/53371/4938/55746/3661/8086/3836/9246/3434/8480/6772/51191/23279/4927/9688/4600/4599/79902/23586 42 Sendai_virus R-HSA-5688426 Deubiquitination 73/603 297/10654 5.918562363835476e-28 7.122003377815355e-26 4.783305957205046e-26 5716/100287144/672/100287478/9960/100287441/1080/64127/8850/55593/3091/84282/3416/367/5701/5688/100287513/11274/5684/4287/7187/7046/27005/4088/7706/8517/728386/8607/580/9146/7186/645836/7416/6885/3054/64135/5728/1540/993/79155/7419/5710/7417/7321/10454/100287404/100287327/8737/7157/4792/9986/10869/983/4087/100287178/5696/63891/4738/7189/55611/2099/57506/100287205/4609/7415/100287364/377630/51720/4193/100287238/392188/7528/23586 73 Sendai_virus R-HSA-1169408 ISG15 antiviral mechanism 37/603 72/10654 1.6381482273535613e-27 1.7741145302239069e-25 1.1915372895803273e-25 23165/9883/9972/348995/9636/79023/57122/23636/5610/11274/5903/23225/7706/8021/10762/55706/7175/129401/23511/9631/53371/55746/3661/8086/3836/9246/3434/8480/6772/51191/23279/4927/9688/4600/4599/79902/23586 37 Sendai_virus R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 26/603 33/10654 6.548249211769536e-27 6.4470489966785525e-25 4.3299906271126795e-25 23165/3303/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/3304/53371/55746/8086/8480/23279/4927/9688/79902 26 Sendai_virus R-HSA-168276 NS1 Mediated Effects on Host Pathways 28/603 40/10654 1.9272778592264616e-26 1.7393682679518816e-24 1.1682008778293729e-24 23165/9883/9972/348995/9636/79023/57122/23636/5610/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/3836/8480/23279/4927/9688/8106/79902 28 Sendai_virus R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 25/603 31/10654 2.1897711638543893e-26 1.8242478234263872e-24 1.2252079953225772e-24 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/3836/8480/23279/4927/9688/79902 25 Sendai_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 26/603 34/10654 2.6374968292098394e-26 2.0402921900244687e-24 1.3703085029954878e-24 7322/55593/84282/9636/54476/79671/5094/7187/7706/84166/9641/7323/9474/64135/1540/7321/54941/83737/3661/9140/9246/29110/57506/51191/3093/23586 26 Sendai_virus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 27/603 38/10654 8.079193850492681e-26 5.833177960055716e-24 3.917700316273995e-24 23165/9883/9972/348995/79023/9063/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/7428/55746/8086/8480/23279/4927/9688/4193/79902 27 Sendai_virus R-HSA-6798695 Neutrophil degranulation 91/603 480/10654 1.0386201523576457e-25 7.030160156270813e-24 4.721621876836402e-24 55004/5908/3916/10694/127829/719/3303/2548/1727/10549/11010/80331/5906/5701/3920/81567/10855/23385/6836/9342/55754/4257/140885/23317/3310/8904/5036/5284/55832/10396/968/9145/3320/9218/4790/326624/847/2357/2495/4311/1938/3728/10576/7097/3304/3312/5660/2040/25798/4718/1915/4126/8673/1088/8895/317/3107/5611/10043/23200/84061/527/203068/5547/9545/10970/8876/401258/5663/150372/1650/5478/8907/374395/10075/79888/5878/154664/2683/353189/6515/54918/967/7520/7415/4973/3106/3326/5580/684/4680 91 Sendai_virus R-HSA-168253 Host Interactions with Influenza Factors 28/603 42/10654 1.6378818859592753e-25 1.0434271073493501e-23 7.007903301534733e-24 23165/9883/9972/348995/9636/79023/57122/23636/5610/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/3836/8480/23279/4927/9688/8106/79902 28 Sendai_virus R-HSA-180746 Nuclear import of Rev protein 25/603 33/10654 3.708727878833534e-25 2.1139748909351145e-23 1.4197955480742228e-23 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/4869/79902 25 Sendai_virus R-HSA-180910 Vpr-mediated nuclear import of PICs 25/603 33/10654 3.708727878833534e-25 2.1139748909351145e-23 1.4197955480742228e-23 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/3836/8480/23279/4927/9688/79902 25 Sendai_virus R-HSA-159227 Transport of the SLBP independent Mature mRNA 25/603 34/10654 1.3278111756368325e-24 6.407213127340439e-23 4.303235914848854e-23 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/10482/53371/55746/8086/8480/23279/4927/9688/79902 25 Sendai_virus R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 24/603 31/10654 1.3607193160556796e-24 6.407213127340439e-23 4.303235914848854e-23 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Sendai_virus R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 24/603 31/10654 1.3607193160556796e-24 6.407213127340439e-23 4.303235914848854e-23 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Sendai_virus R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 24/603 31/10654 1.3607193160556796e-24 6.407213127340439e-23 4.303235914848854e-23 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Sendai_virus R-HSA-168898 Toll-like Receptor Cascades 49/603 155/10654 2.9743435628416618e-24 1.3421725327323e-22 9.014348254050827e-23 7322/54106/8454/1147/2353/64127/3665/5598/8945/23118/7187/351/841/10333/7099/8517/8772/4615/81793/9641/7098/7100/4790/6885/5599/7323/7097/3551/79155/7184/7321/10454/7096/8737/5970/4792/3661/4793/3654/4791/29110/7189/51231/6285/51284/51311/10010/148022/4214 49 Sendai_virus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 25/603 35/10654 4.4043230386678214e-24 1.8345699426450963e-22 1.2321405747852084e-22 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/10482/53371/55746/8086/8480/23279/4927/9688/79902 25 Sendai_virus R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 25/603 35/10654 4.4043230386678214e-24 1.8345699426450963e-22 1.2321405747852084e-22 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/983/8086/8480/23279/4927/9688/79902 25 Sendai_virus R-HSA-176033 Interactions of Vpr with host cellular proteins 25/603 36/10654 1.366040730087636e-23 5.283650395303249e-22 3.548624603347957e-22 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/3836/8480/23279/4927/9688/79902 25 Sendai_virus R-HSA-177243 Interactions of Rev with host cellular proteins 25/603 36/10654 1.366040730087636e-23 5.283650395303249e-22 3.548624603347957e-22 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/4869/79902 25 Sendai_virus R-HSA-2980766 Nuclear Envelope Breakdown 29/603 52/10654 3.651398499973574e-23 1.363608474300476e-21 9.158317108826642e-22 23165/9883/9972/348995/79023/57122/23636/5903/5347/23225/8021/7443/10762/55706/7175/5579/129401/23511/9631/53371/55746/983/7112/8086/8480/23279/4927/9688/79902 29 Sendai_virus R-HSA-165054 Rev-mediated nuclear export of HIV RNA 24/603 34/10654 5.775709612449682e-23 2.0177721000912922e-21 1.3551834778277524e-21 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Sendai_virus R-HSA-4085377 SUMOylation of SUMOylation proteins 24/603 34/10654 5.775709612449682e-23 2.0177721000912922e-21 1.3551834778277524e-21 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Sendai_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 37/603 94/10654 2.289377824355305e-22 7.748113074302486e-21 5.20381604154446e-21 7322/8454/1147/2353/64127/3665/5598/8945/23118/7187/351/841/8517/8772/9641/7098/4790/6885/5599/7323/3551/79155/7321/10454/8737/5970/4792/3661/4793/3654/4791/29110/7189/51231/6285/10010/148022 37 Sendai_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 42/603 129/10654 1.717351135651719e-21 5.636034181547914e-20 3.7852938907028316e-20 7322/8454/1147/2353/64127/3665/5598/8945/23118/7187/351/841/10333/7099/8517/8772/4615/9641/4790/6885/5599/7323/7097/3551/79155/7321/10454/7096/8737/5970/4792/3661/4793/3654/4791/29110/7189/51231/6285/10010/148022/4214 42 Sendai_virus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 25/603 41/10654 1.7916995520944972e-21 5.707090043877472e-20 3.833016688846122e-20 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/10482/53371/55746/8086/8480/23279/4927/9688/79902 25 Sendai_virus R-HSA-166166 MyD88-independent TLR4 cascade 37/603 99/10654 1.936832790256686e-21 5.826638644022197e-20 3.9133083569221346e-20 7322/8454/1147/2353/64127/3665/5598/8945/23118/7187/351/841/7099/8517/8772/9641/4790/6885/5599/7323/3551/79155/7321/10454/8737/5970/4792/3661/4793/3654/4791/29110/7189/51231/6285/10010/148022 37 Sendai_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 37/603 99/10654 1.936832790256686e-21 5.826638644022197e-20 3.9133083569221346e-20 7322/8454/1147/2353/64127/3665/5598/8945/23118/7187/351/841/7099/8517/8772/9641/4790/6885/5599/7323/3551/79155/7321/10454/8737/5970/4792/3661/4793/3654/4791/29110/7189/51231/6285/10010/148022 37 Sendai_virus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 25/603 42/10654 4.195073762870568e-21 1.2279094284294124e-19 8.246930213779695e-20 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/10482/53371/55746/8086/8480/23279/4927/9688/79902 25 Sendai_virus R-HSA-5689880 Ub-specific processing proteases 54/603 220/10654 7.988737664473076e-21 2.2767902343748264e-19 1.5291461845293338e-19 5716/100287144/100287478/9960/100287441/1080/3091/3416/367/5701/5688/100287513/11274/5684/7046/27005/4088/8517/728386/8607/9146/7186/645836/7416/6885/64135/5728/1540/993/7419/5710/7417/10454/100287404/100287327/8737/7157/4792/9986/10869/4087/100287178/5696/63891/7189/55611/100287205/4609/100287364/377630/4193/100287238/392188/23586 54 Sendai_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 48/603 182/10654 4.9761277978003284e-20 1.3818324115430143e-18 9.280713382672139e-19 672/23165/9883/367/9972/348995/79023/9063/57122/23636/5893/5903/23225/8517/2908/8021/9641/7068/10762/55706/7175/129401/23511/9631/7067/1029/11315/53371/7428/3066/3065/7157/5970/4792/3190/55746/8086/1786/4791/6672/8480/2099/23279/4927/9688/4193/4869/79902 48 Sendai_virus R-HSA-162909 Host Interactions of HIV factors 40/603 129/10654 1.1963616424638837e-19 3.239149146970965e-18 2.1754891972172205e-18 5716/60489/23165/9883/9972/348995/8945/5701/5688/79023/57122/23636/5684/5903/8065/23225/8021/10762/55706/7175/162/129401/23511/9631/9978/5710/53371/55746/8086/5478/5696/8907/3836/8480/23279/4927/1174/9688/4869/79902 40 Sendai_virus R-HSA-4570464 SUMOylation of RNA binding proteins 25/603 47/10654 1.8681002602013755e-19 4.934518492190462e-18 3.314139357635816e-18 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/3190/55746/8086/8480/23279/4927/9688/79902 25 Sendai_virus R-HSA-168325 Viral Messenger RNA Synthesis 24/603 43/10654 2.174394684145047e-19 5.4953674428112e-18 3.690818781146464e-18 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Sendai_virus R-HSA-2990846 SUMOylation 48/603 188/10654 2.1819095109961367e-19 5.4953674428112e-18 3.690818781146464e-18 672/23165/9883/367/9972/348995/79023/9063/57122/23636/5893/5903/23225/8517/2908/8021/9641/7068/10762/55706/7175/129401/23511/9631/7067/1029/11315/53371/7428/3066/3065/7157/5970/4792/3190/55746/8086/1786/4791/6672/8480/2099/23279/4927/9688/4193/4869/79902 48 Sendai_virus R-HSA-4615885 SUMOylation of DNA replication proteins 24/603 45/10654 9.206765896315427e-19 2.2661198785703655e-17 1.5219797211373113e-17 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Sendai_virus R-HSA-933542 TRAF6 mediated NF-kB activation 18/603 24/10654 2.723069002919567e-18 6.553519400359758e-17 4.401498669046599e-17 1147/84282/351/7706/8517/7186/4790/64135/3551/5970/4792/4793/4791/7189/6285/57506/4214/23586 18 Sendai_virus R-HSA-191859 snRNP Assembly 25/603 53/10654 8.247551270327933e-18 1.9004463884606707e-16 1.2763847542657564e-16 23165/9883/9972/348995/79023/6635/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 25 Sendai_virus R-HSA-194441 Metabolism of non-coding RNA 25/603 53/10654 8.247551270327933e-18 1.9004463884606707e-16 1.2763847542657564e-16 23165/9883/9972/348995/79023/6635/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 25 Sendai_virus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 29/603 77/10654 3.576322318087838e-17 8.069077230185685e-16 5.419383161839246e-16 672/23165/9883/9972/348995/79023/9063/57122/23636/5893/5903/23225/8021/10762/55706/7175/129401/23511/9631/1029/53371/55746/8086/6672/8480/23279/4927/9688/79902 29 Sendai_virus R-HSA-5260271 Diseases of Immune System 17/603 24/10654 1.2055323349236702e-16 2.6111830374446695e-15 1.7537323019626447e-15 1147/7187/10333/7099/8517/4615/81793/7098/7100/4790/7097/3551/7096/5970/4792/4791/148022 17 Sendai_virus R-HSA-5602358 Diseases associated with the TLR signaling cascade 17/603 24/10654 1.2055323349236702e-16 2.6111830374446695e-15 1.7537323019626447e-15 1147/7187/10333/7099/8517/4615/81793/7098/7100/4790/7097/3551/7096/5970/4792/4791/148022 17 Sendai_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 31/603 93/10654 1.6654517931870138e-16 3.468623638502954e-15 2.329609694518677e-15 54106/8454/1147/2353/64127/3665/5598/8945/23118/351/7099/8517/4615/4790/6885/5599/3551/79155/10454/5970/4792/4793/3654/4791/7189/51231/6285/51284/51311/148022/4214 31 Sendai_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 31/603 93/10654 1.6654517931870138e-16 3.468623638502954e-15 2.329609694518677e-15 54106/8454/1147/2353/64127/3665/5598/8945/23118/351/7099/8517/4615/4790/6885/5599/3551/79155/10454/5970/4792/4793/3654/4791/7189/51231/6285/51284/51311/148022/4214 31 Sendai_virus R-HSA-4551638 SUMOylation of chromatin organization proteins 27/603 71/10654 3.3525988224875965e-16 6.850687782554843e-15 4.601083984784368e-15 23165/9883/9972/348995/79023/9063/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/3066/3065/55746/8086/8480/23279/4927/9688/79902 27 Sendai_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 31/603 97/10654 6.459448824483202e-16 1.295478347576909e-14 8.700739059878933e-15 54106/8454/1147/2353/64127/3665/5598/8945/23118/351/7099/8517/4615/4790/6885/5599/3551/79155/10454/5970/4792/4793/3654/4791/7189/51231/6285/51284/51311/148022/4214 31 Sendai_virus R-HSA-6784531 tRNA processing in the nucleus 24/603 57/10654 9.634501940551545e-16 1.8834210263639084e-14 1.2649501183043793e-14 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Sendai_virus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12/603 12/10654 9.738834485353542e-16 1.8834210263639084e-14 1.2649501183043793e-14 1147/84282/843/841/7706/8517/8772/64135/3551/8737/57506/23586 12 Sendai_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 30/603 92/10654 1.0275931430738064e-15 1.9524269718402323e-14 1.3112961437931675e-14 54106/8454/1147/2353/64127/5598/8945/23118/351/7099/8517/4615/4790/6885/5599/3551/79155/10454/5970/4792/4793/3654/4791/7189/51231/6285/51284/51311/148022/4214 30 Sendai_virus R-HSA-70171 Glycolysis 26/603 71/10654 3.5102063848063234e-15 6.554402611629738e-14 4.402091854630072e-14 23165/9883/9972/348995/79023/2023/57122/23636/5903/23225/8021/2597/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 26 Sendai_virus R-HSA-5689896 Ovarian tumor domain proteases 19/603 38/10654 1.960078355784409e-14 3.5979065412110423e-13 2.416439150485329e-13 64127/55593/84282/7187/7706/8517/64135/5728/79155/7321/8737/7157/983/7189/55611/2099/57506/7415/23586 19 Sendai_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 29/603 95/10654 2.207054021714756e-14 3.9184254188804606e-13 2.631707211397578e-13 8454/1147/2353/64127/5598/8945/23118/351/10333/7099/8517/4615/4790/6885/5599/7097/3551/79155/10454/7096/5970/4792/4793/3654/4791/7189/51231/6285/4214 29 Sendai_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 29/603 95/10654 2.207054021714756e-14 3.9184254188804606e-13 2.631707211397578e-13 8454/1147/2353/64127/5598/8945/23118/351/10333/7099/8517/4615/4790/6885/5599/7097/3551/79155/10454/7096/5970/4792/4793/3654/4791/7189/51231/6285/4214 29 Sendai_virus R-HSA-168254 Influenza Infection 37/603 155/10654 3.3302507672122805e-14 5.817196098211129e-13 3.906966519768567e-13 23165/3303/9883/9972/811/348995/9636/79023/1213/57122/23636/5610/5903/23225/3921/6188/8021/3320/10762/55706/7175/129401/23511/9631/3304/53371/5611/55746/8086/3836/8480/23279/4927/9688/8106/79902/821 37 Sendai_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 29/603 98/10654 5.453370596890007e-14 9.22812555692481e-13 6.197827438241768e-13 8454/1147/2353/64127/5598/8945/23118/351/10333/7099/8517/4615/4790/6885/5599/7097/3551/79155/10454/7096/5970/4792/4793/3654/4791/7189/51231/6285/4214 29 Sendai_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 29/603 98/10654 5.453370596890007e-14 9.22812555692481e-13 6.197827438241768e-13 8454/1147/2353/64127/5598/8945/23118/351/10333/7099/8517/4615/4790/6885/5599/7097/3551/79155/10454/7096/5970/4792/4793/3654/4791/7189/51231/6285/4214 29 Sendai_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 27/603 85/10654 5.920294228641894e-14 9.56966962629727e-13 6.427216515304868e-13 8454/1147/2353/64127/5598/8945/23118/351/8517/4615/81793/7100/4790/6885/5599/3551/79155/10454/5970/4792/4793/3654/4791/7189/51231/6285/4214 27 Sendai_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 27/603 85/10654 5.920294228641894e-14 9.56966962629727e-13 6.427216515304868e-13 8454/1147/2353/64127/5598/8945/23118/351/8517/4615/81793/7100/4790/6885/5599/3551/79155/10454/5970/4792/4793/3654/4791/7189/51231/6285/4214 27 Sendai_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 27/603 85/10654 5.920294228641894e-14 9.56966962629727e-13 6.427216515304868e-13 8454/1147/2353/64127/5598/8945/23118/351/8517/4615/81793/7100/4790/6885/5599/3551/79155/10454/5970/4792/4793/3654/4791/7189/51231/6285/4214 27 Sendai_virus R-HSA-3371568 Attenuation phase 12/603 14/10654 7.977113423578527e-14 1.2520599764834123e-12 8.409131007921834e-13 3306/3303/3281/3337/3320/3304/3312/3305/3297/2288/10728/3326 12 Sendai_virus R-HSA-918233 TRAF3-dependent IRF activation pathway 12/603 14/10654 7.977113423578527e-14 1.2520599764834123e-12 8.409131007921834e-13 3665/84282/7187/7706/9641/80143/64135/3456/3661/29110/57506/23586 12 Sendai_virus R-HSA-3371571 HSF1-dependent transactivation 15/603 24/10654 1.3449600763583466e-13 2.0808453752801276e-12 1.3975449815994248e-12 2475/3306/3303/1410/3281/3337/3320/3304/3312/3305/3297/57521/2288/10728/3326 15 Sendai_virus R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 25/603 75/10654 1.4720579222141047e-13 2.2454066616308104e-12 1.5080682346181563e-12 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/10482/53371/55746/8086/8480/23279/4927/9688/79902 25 Sendai_virus R-HSA-9020702 Interleukin-1 signaling 29/603 103/10654 2.2655297518736161e-13 3.4077343351098973e-12 2.288714997872323e-12 5716/8454/1147/64127/8945/5701/23118/5688/5684/351/8517/4615/4790/6885/4215/9978/3551/79155/5710/10454/5970/4792/5696/4793/3654/4791/7189/6285/8878 29 Sendai_virus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 14/603 21/10654 2.4057552701036566e-13 3.569086243181178e-12 2.3970827565127998e-12 1147/8517/4615/7098/4790/3551/8737/5970/4792/3661/4793/4791/29110/148022 14 Sendai_virus R-HSA-5663205 Infectious disease 60/603 383/10654 3.3548717278603135e-13 4.909900109827999e-12 3.2976050696322567e-12 5716/60489/23165/3303/9883/9972/811/348995/8945/5701/9636/867/5688/79023/1213/57122/23636/5610/5684/5903/8065/23225/3921/6188/8021/9146/3320/10762/128866/55706/7175/162/129401/23511/9631/1938/3304/9978/5710/801/53371/5611/4233/55746/8086/5478/5696/8907/3836/8480/23279/4927/1174/9688/7520/8106/3326/4869/79902/821 60 Sendai_virus R-HSA-449147 Signaling by Interleukins 67/603 461/10654 4.916780209597212e-13 7.099830622658374e-12 4.768414210290068e-12 5716/8454/5908/1147/2353/64127/5743/5598/3091/8945/5701/23118/867/25930/5688/6950/5684/351/29760/4088/4478/8517/836/4615/3313/3320/4790/3662/4843/6885/5599/2357/4985/4215/9978/3312/3551/79155/5710/6773/3458/7184/10454/7157/5970/4792/4170/207/5478/5696/5292/4793/3627/3654/3586/7422/4791/29110/7189/6772/51231/6285/8878/4609/4582/6647/821 67 Sendai_virus R-HSA-877300 Interferon gamma signaling 27/603 92/10654 5.1149190172786e-13 7.288759599622005e-12 4.895303380802649e-12 3135/3665/4939/3133/8638/7706/3134/10379/2634/4940/3662/3394/3458/4938/3107/3663/3664/3105/3661/2633/3660/6672/85363/6772/3659/3106/5580 27 Sendai_virus R-HSA-168255 Influenza Life Cycle 34/603 144/10654 5.253239548166885e-13 7.388647312551607e-12 4.962390331897906e-12 23165/3303/9883/9972/811/348995/79023/1213/57122/23636/5903/23225/3921/6188/8021/3320/10762/55706/7175/129401/23511/9631/3304/53371/5611/55746/8086/3836/8480/23279/4927/9688/79902/821 34 Sendai_virus R-HSA-446652 Interleukin-1 family signaling 33/603 140/10654 1.223434214893775e-12 1.6986913522178954e-11 1.14088129890904e-11 5716/8454/1147/64127/8945/5701/23118/25930/5688/5684/351/4088/8517/4615/4790/6885/5599/4215/9978/3551/79155/5710/10454/5970/4792/5696/4793/3654/4791/29110/7189/6285/8878 33 Sendai_virus R-HSA-72202 Transport of Mature Transcript to Cytoplasm 25/603 84/10654 2.659808957822046e-12 3.64629506496364e-11 2.448938027788186e-11 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/10482/53371/55746/8086/8480/23279/4927/9688/79902 25 Sendai_virus R-HSA-70326 Glucose metabolism 26/603 91/10654 2.76427801043041e-12 3.742141356620167e-11 2.5133106647465964e-11 23165/9883/9972/348995/79023/2023/57122/23636/5903/23225/8021/2597/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 26 Sendai_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 16/603 33/10654 4.327072584454826e-12 5.7854563073636746e-11 3.885649325351897e-11 1147/64127/23118/351/8517/4790/6885/3551/10454/5970/4792/4793/3654/4791/7189/6285 16 Sendai_virus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 12/603 17/10654 4.632789971082427e-12 6.118672608149108e-11 4.1094452760179165e-11 1147/8517/4615/7098/4790/3551/8737/5970/4792/4793/4791/148022 12 Sendai_virus R-HSA-933541 TRAF6 mediated IRF7 activation 15/603 29/10654 6.116996974257925e-12 7.981575570025702e-11 5.360614976806882e-11 3665/84282/7706/9641/7186/80143/64135/3440/3456/3661/29110/7189/57506/10010/23586 15 Sendai_virus R-HSA-162906 HIV Infection 42/603 233/10654 1.470789149676718e-11 1.8962674394046254e-10 1.273578073216306e-10 5716/60489/23165/9883/9972/348995/8945/5701/5688/79023/57122/23636/5684/5903/8065/23225/8021/10762/128866/55706/7175/162/129401/23511/9631/9978/5710/53371/55746/8086/5478/5696/8907/3836/8480/23279/4927/1174/9688/7520/4869/79902 42 Sendai_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 26/603 101/10654 3.7445568146538947e-11 4.771005917964903e-10 3.2043204444902064e-10 7322/5716/8454/1147/8945/5701/23118/5688/5684/841/8517/4790/6885/3551/5710/801/7321/10454/5970/4792/9040/5696/997/4791/7189/5580 26 Sendai_virus R-HSA-5663202 Diseases of signal transduction 55/603 377/10654 6.067931207837418e-11 7.641359881497586e-10 5.132118071744989e-10 2475/5716/10014/8454/5908/1147/8850/2932/5906/2261/5701/867/10013/5688/23385/2064/5684/7046/1956/4088/8841/11160/3320/2100/5728/673/9978/10018/9611/55869/5710/801/3066/3065/4296/4233/5663/5894/207/4087/5696/57085/7750/1452/5245/6772/2099/6934/3280/9530/4609/253260/7415/613/4193 55 Sendai_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 19/603 55/10654 6.267238105720411e-11 7.801630883327823e-10 5.239759868182461e-10 7295/1147/64127/23118/351/841/8517/4790/6885/1540/3551/10454/5970/83737/10910/3654/4791/7189/3326 19 Sendai_virus R-HSA-72306 tRNA processing 26/603 107/10654 1.5108269224757987e-10 1.8593472239105567e-9 1.2487815830511685e-9 23165/9883/9972/348995/55039/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/90353/8480/23279/4927/9688/79902 26 Sendai_virus R-HSA-5619115 Disorders of transmembrane transporters 34/603 176/10654 1.9797126064110648e-10 2.4090210704979586e-9 1.617955542318209e-9 5716/1080/23165/9883/9972/348995/5701/5688/79023/57122/23636/5684/5903/23225/11160/8021/10762/1244/55706/7175/129401/23511/9631/5710/53371/55746/8086/5696/8480/23279/4927/9688/7415/79902 34 Sendai_virus R-HSA-73887 Death Receptor Signalling 30/603 141/10654 2.0133598334790582e-10 2.4227429996198e-9 1.6271715145427243e-9 1147/23118/23385/843/841/27005/8841/8517/8772/836/4615/331/7186/4790/6885/5599/1540/10018/3551/10454/3066/3065/8737/5970/4792/5663/3654/7189/9530/8878 30 Sendai_virus R-HSA-983169 Class I MHC mediated antigen processing & presentation 53/603 371/10654 3.043398492317618e-10 3.6219786452527256e-9 2.4326065450450827e-9 7322/5716/8454/1147/3135/23295/811/3133/8945/5701/5688/140462/26259/5684/8065/10333/7099/8517/3134/4615/3309/8452/7323/5930/7097/9978/55008/3551/5710/8673/151636/3107/7321/7096/7428/22954/7332/83737/3105/9040/10273/5696/997/63891/10075/7337/9246/10484/84676/51191/3106/3093/821 53 Sendai_virus R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 18/603 55/10654 5.563105745454421e-10 6.548742959051237e-9 4.398290698065223e-9 3306/10294/3303/830/367/3337/2908/3320/3304/3312/3305/3301/55466/2288/10963/2289/10728/3326 18 Sendai_virus R-HSA-1236974 ER-Phagosome pathway 22/603 83/10654 6.628481845928707e-10 7.718974020581494e-9 5.184245563708813e-9 5716/1147/3135/811/3133/5701/5688/5684/10333/7099/8517/3134/4615/7097/3551/5710/8673/3107/7096/3105/5696/3106 22 Sendai_virus R-HSA-5619102 SLC transporter disorders 24/603 99/10654 8.148347112689883e-10 9.387936088343768e-9 6.305159971857457e-9 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Sendai_virus R-HSA-68875 Mitotic Prophase 29/603 142/10654 1.1248068885452058e-9 1.2822798529415347e-8 8.612094847476314e-9 23165/9883/9972/348995/79023/57122/23636/5903/5347/23225/8021/7443/10762/55706/7175/5579/129401/23511/9631/53371/55746/983/7112/8086/8480/23279/4927/9688/79902 29 Sendai_virus R-HSA-168273 Influenza Viral RNA Transcription and Replication 28/603 134/10654 1.2623935968011159e-009 1.424137776391259e-8 9.564846221376877e-9 23165/9883/9972/348995/79023/57122/23636/5903/23225/3921/6188/8021/3320/10762/55706/7175/129401/23511/9631/53371/5611/55746/8086/8480/23279/4927/9688/79902 28 Sendai_virus R-HSA-2871837 FCERI mediated NF-kB activation 21/603 82/10654 3.2183408256181377e-9 3.5932609424169516e-008 2.413319056432049e-8 7322/5716/8454/1147/8945/5701/23118/5688/5684/8517/4790/6885/3551/5710/7321/10454/5970/4792/5696/997/7189 21 Sendai_virus R-HSA-5578749 Transcriptional regulation by small RNAs 24/603 106/10654 3.5881435323540623e-9 3.965264740346377e-8 2.6631656077944762e-8 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 24 Sendai_virus R-HSA-390450 Folding of actin by CCT/TriC 8/603 10/10654 4.095376065277833e-9 4.480093210803932e-8 3.008936588098865e-8 10694/6950/22948/7203/10576/908/10575/10574 8 Sendai_virus R-HSA-5621481 C-type lectin receptors (CLRs) 28/603 142/10654 5.006608584327822e-9 5.422157096827031e-8 3.641648980811079e-8 7322/5716/8454/1147/8945/5701/23118/5688/5684/841/8517/4790/6885/3551/5710/801/7321/10454/5970/4792/9040/5894/5696/997/4791/7189/4582/5580 28 Sendai_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 18/603 63/10654 6.523830687623808e-9 6.995355083858004e-8 4.698245966803598e-8 1147/3665/8517/4615/7098/4790/3551/22954/8737/5970/4792/3661/4793/4791/29110/3428/7520/148022 18 Sendai_virus R-HSA-1169091 Activation of NF-kappaB in B cells 18/603 67/10654 1.9069246316367586e-8 2.024705270649617e-7 1.3598399591960789e-7 5716/8454/1147/8945/5701/5688/5684/8517/4790/6885/5579/5966/3551/5710/5970/4792/5696/4793 18 Sendai_virus R-HSA-1236975 Antigen processing-Cross presentation 22/603 99/10654 2.326633200849268e-8 2.446353161669667e-7 1.6430286579323905e-7 5716/1147/3135/811/3133/5701/5688/5684/10333/7099/8517/3134/4615/7097/3551/5710/8673/3107/7096/3105/5696/3106 22 Sendai_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 20/603 83/10654 2.362250188061669e-8 2.459920147760373e-7 1.6521405667516332e-7 5716/8454/1147/8945/5701/5688/5684/8517/4790/6885/5579/5966/3551/5710/801/5970/4792/5478/5696/4793 20 Sendai_virus R-HSA-162587 HIV Life Cycle 28/603 152/10654 2.4041795156851383e-8 2.479739443320957e-7 1.6654516745247426e-7 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/128866/55706/7175/129401/23511/9631/53371/55746/8086/5478/3836/8480/23279/4927/9688/7520/79902 28 Sendai_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 10/603 20/10654 3.4558707406886e-8 3.530856615250711e-7 2.3714068339779768e-7 7322/1147/8517/7098/7323/3551/7321/8737/7189/148022 10 Sendai_virus R-HSA-3371511 HSF1 activation 8/603 12/10654 4.0690380195643036e-8 4.0803409029519823e-7 2.740453481012606e-7 10013/3281/3320/1915/3297/10728/7415/3326 8 Sendai_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 8/603 12/10654 4.0690380195643036e-8 4.0803409029519823e-7 2.740453481012606e-7 3665/7187/9641/7098/3661/29110/10010/148022 8 Sendai_virus R-HSA-75893 TNF signaling 14/603 43/10654 5.065755675317049e-8 5.033223299420517e-7 3.3804318412786877e-7 1147/23118/841/27005/8517/8772/331/7186/6885/1540/3551/10454/8737/9530 14 Sendai_virus R-HSA-162599 Late Phase of HIV Life Cycle 26/603 139/10654 5.5229989681653204e-8 5.437643529566402e-7 3.652050035408839e-7 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/10762/128866/55706/7175/129401/23511/9631/53371/55746/8086/5478/8480/23279/4927/9688/79902 26 Sendai_virus R-HSA-450294 MAP kinase activation 17/603 64/10654 5.7000878354558095e-8 5.561437050269046e-7 3.7351926925556797e-7 8454/1147/2353/64127/5598/8945/23118/8517/4790/6885/5599/3551/79155/10454/3654/7189/51231 17 Sendai_virus R-HSA-202424 Downstream TCR signaling 21/603 98/10654 9.481682917318548e-8 9.168448749514275e-7 6.157747082581877e-7 7322/5716/8454/1147/8945/5701/23118/5688/5684/8517/4790/6885/5728/3551/5710/7321/5970/4792/5696/997/7189 21 Sendai_virus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 36/603 244/10654 1.0432056640914407e-7 9.973440624013485e-7 6.69839866957605e-7 23165/9883/9972/348995/79023/6635/57122/23636/5094/5903/23225/8021/10762/55706/7175/129401/23511/10594/9631/3312/10713/10482/53371/9343/3190/55746/8086/56339/56259/8480/23279/4927/9688/3184/8106/79902 36 Sendai_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 25/603 134/10654 1.0498358551593142e-7 9.973440624013485e-7 6.69839866957605e-7 7322/5716/8454/1147/2353/8945/5701/23118/5688/5684/8517/4790/6885/5599/3551/5710/801/7321/10454/5970/4792/5696/997/7189/4214 25 Sendai_virus R-HSA-211000 Gene Silencing by RNA 25/603 136/10654 1.4180958708866482e-7 1.3354763723219477e-6 8.969375256591982e-7 23165/9883/9972/348995/79023/57122/23636/5903/23225/8021/3320/10762/55706/7175/129401/23511/9631/53371/55746/8086/8480/23279/4927/9688/79902 25 Sendai_virus R-HSA-109581 Apoptosis 29/603 178/10654 2.2040168627168684e-7 2.0577157433813523e-6 1.382010573627365e-6 5716/7161/5701/5688/5684/841/7099/8772/836/331/581/7186/5599/7159/10018/4137/1029/5710/317/3002/8737/7157/207/54205/5696/3836/10059/148022/5580 29 Sendai_virus R-HSA-1257604 PIP3 activates AKT signaling 37/603 264/10654 2.6350268698885887e-7 2.439088974435335e-6 1.6381498579334366e-6 2475/5716/10014/55004/1147/1958/2932/2261/5701/5688/2064/5684/1956/8841/4615/331/4343/2100/23035/5728/23186/5710/6615/3066/3065/7157/1457/4233/57521/10273/207/5696/3654/7189/2099/253260/4193 37 Sendai_virus R-HSA-5357801 Programmed Cell Death 29/603 181/10654 3.1779231788069105e-7 2.9166871208880372e-6 1.9589160718604596e-6 5716/7161/5701/5688/5684/841/7099/8772/836/331/581/7186/5599/7159/10018/4137/1029/5710/317/3002/8737/7157/207/54205/5696/3836/10059/148022/5580 29 Sendai_virus R-HSA-168638 NOD1/2 Signaling Pathway 12/603 36/10654 3.4604665406171947e-7 3.149315347469262e-6 2.115154692230413e-6 1147/64127/23118/841/8517/6885/1540/3551/10454/83737/3654/7189 12 Sendai_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 11/603 30/10654 3.548461080516766e-7 3.202486125166381e-6 2.150865444418496e-6 1147/23118/27005/8517/331/7186/6885/1540/3551/10454/8737 11 Sendai_virus R-HSA-448424 Interleukin-17 signaling 17/603 72/10654 3.663032871598972e-7 3.278565785075774e-6 2.201962343866803e-6 8454/1147/2353/64127/5598/8945/23118/8517/4790/6885/5599/3551/79155/10454/3654/7189/51231 17 Sendai_virus R-HSA-937041 IKK complex recruitment mediated by RIP1 10/603 25/10654 4.7206994450132426e-7 4.156518291828733e-6 2.791616017547412e-6 7322/1147/7099/8517/7323/3551/7321/8737/7189/148022 10 Sendai_virus R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 10/603 25/10654 4.7206994450132426e-7 4.156518291828733e-6 2.791616017547412e-6 3135/811/3133/3134/3309/3107/3105/10484/3106/821 10 Sendai_virus R-HSA-9006925 Intracellular signaling by second messengers 40/603 305/10654 5.148240384758669e-7 4.496406723140031e-6 3.019893128920408e-6 2475/5716/10014/5582/55004/1147/1958/2932/2261/5701/5688/2064/5684/1956/8841/4615/331/4343/2100/23035/5728/23186/5710/801/6615/3066/3065/7157/1457/4233/57521/10273/207/5696/3654/7189/2099/253260/4193/5580 40 Sendai_virus R-HSA-202403 TCR signaling 22/603 119/10654 7.195009343984356e-7 6.184281840900839e-6 4.153509988883199e-6 7322/5716/8454/1147/8945/5701/23118/5688/5684/8517/4790/6885/5728/3551/5710/7321/5970/4792/5696/997/7189/7535 22 Sendai_virus R-HSA-9612973 Autophagy 22/603 119/10654 7.195009343984356e-7 6.184281840900839e-6 4.153509988883199e-6 2475/55004/1080/3920/10013/5562/3320/128866/7416/9474/65018/3312/139341/11315/1915/1457/57521/55054/9140/8878/3326/10452 22 Sendai_virus R-HSA-193639 p75NTR signals via NF-kB 8/603 16/10654 8.634486881862229e-7 7.36310967957228e-6 4.945238653432906e-6 4615/4790/3551/5970/4792/3654/7189/8878 8 Sendai_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 14/603 53/10654 9.171435359716071e-7 7.75989413638477e-6 5.211728481549182e-6 7161/841/836/331/581/5599/7159/10018/1029/317/3002/7157/207/54205 14 Sendai_virus R-HSA-8878166 Transcriptional regulation by RUNX2 22/603 121/10654 9.676250626853728e-7 8.123549944870223e-6 5.45596832570863e-6 5716/8454/367/2932/5701/10013/5688/25/5684/8841/2908/581/9978/5710/983/10273/207/5696/10413/6772/2099/3280 22 Sendai_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 21/603 112/10654 1.0094511552463832e-6 8.409504624091023e-6 5.648022253240898e-6 5716/8454/1147/8945/5701/5688/5684/29760/8517/4790/6885/5579/5966/3551/5710/801/5970/4792/5478/5696/4793 21 Sendai_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 13/603 47/10654 1.269390137232517e-6 1.0494271134525313e-5 7.048200761974041e-6 10014/8454/8850/3091/10013/8841/9978/9611/55869/3066/3065/3280/4609 13 Sendai_virus R-HSA-5620922 BBSome-mediated cargo-targeting to cilium 9/603 23/10654 2.24220592144771e-6 1.839628040096871e-5 1.235537712695668e-5 10694/79738/6950/22948/7203/10576/8195/10575/6753 9 Sendai_virus R-HSA-209560 NF-kB is activated and signals survival 7/603 13/10654 2.2867132174439283e-6 1.862037905632913e-5 1.2505887085506566e-5 4790/3551/5970/4792/3654/7189/8878 7 Sendai_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 16/603 73/10654 2.339221388416754e-6 1.8765753804854404e-5 1.2603524205816583e-5 867/7046/4088/7323/9611/5501/7321/3065/9040/10273/4087/5499/4738/5500/4609/4221 16 Sendai_virus R-HSA-1980143 Signaling by NOTCH1 16/603 73/10654 2.339221388416754e-6 1.8765753804854404e-5 1.2603524205816583e-5 10014/8454/8850/3091/10013/23385/8841/9978/9611/55869/3066/3065/83737/5663/3280/4609 16 Sendai_virus R-HSA-9614085 FOXO-mediated transcription 15/603 65/10654 2.431525562771791e-6 1.93628101800136e-5 1.3004521392223744e-5 7295/8850/4287/23411/4088/2908/847/65018/10018/3066/3065/207/4087/84676/23410 15 Sendai_virus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 8/603 18/10654 2.652673279344779e-6 2.09696727119007e-5 1.4083728282959988e-5 3665/7187/7099/9641/3661/29110/10010/148022 8 Sendai_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 14/603 58/10654 2.974383594091455e-6 2.268491149578201e-5 1.523572322844474e-5 10014/8454/8850/10013/23385/8841/9978/9611/55869/3066/3065/5663/3280/4609 14 Sendai_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 14/603 58/10654 2.974383594091455e-6 2.268491149578201e-5 1.523572322844474e-5 10014/8454/8850/10013/23385/8841/9978/9611/55869/3066/3065/5663/3280/4609 14 Sendai_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 14/603 58/10654 2.974383594091455e-6 2.268491149578201e-5 1.523572322844474e-5 10014/8454/8850/10013/23385/8841/9978/9611/55869/3066/3065/5663/3280/4609 14 Sendai_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 14/603 58/10654 2.974383594091455e-6 2.268491149578201e-5 1.523572322844474e-5 10014/8454/8850/10013/23385/8841/9978/9611/55869/3066/3065/5663/3280/4609 14 Sendai_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 14/603 58/10654 2.974383594091455e-6 2.268491149578201e-5 1.523572322844474e-5 10014/8454/8850/10013/23385/8841/9978/9611/55869/3066/3065/5663/3280/4609 14 Sendai_virus R-HSA-6807070 PTEN Regulation 23/603 140/10654 3.4167264320569426e-6 2.587632675466901e-5 1.7379153217161188e-5 2475/5716/10014/55004/1958/5701/5688/5684/8841/331/4343/5728/23186/5710/6615/3066/3065/7157/1457/57521/10273/207/5696 23 Sendai_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 10/603 32/10654 6.492283623502609e-6 4.8827383085092536e-5 3.279362561286771e-5 867/7046/4088/5501/9040/10273/4087/5499/4738/5500 10 Sendai_virus R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 11/603 39/10654 6.822141775187157e-6 5.095434167260477e-5 3.4222141318724686e-5 10694/6950/8841/22948/7203/10576/2629/908/7157/10575/10574 11 Sendai_virus R-HSA-844456 The NLRP3 inflammasome 7/603 15/10654 7.759632397477634e-6 5.716790398958012e-5 3.8395316768041865e-5 7295/351/4790/5970/10910/4791/3326 7 Sendai_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 7/603 15/10654 7.759632397477634e-6 5.716790398958012e-5 3.8395316768041865e-5 54106/3665/4615/3654/7189/51284/51311 7 Sendai_virus R-HSA-1236977 Endosomal/Vacuolar pathway 6/603 11/10654 1.1601492579391494e-5 8.432494270792609e-5 5.6634626438428285e-5 3135/3133/3134/3107/3105/3106 6 Sendai_virus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 6/603 11/10654 1.1601492579391494e-5 8.432494270792609e-5 5.6634626438428285e-5 23118/7098/6885/10454/7189/148022 6 Sendai_virus R-HSA-68886 M Phase 44/603 395/10654 1.167972232776083e-5 8.4327595206433193e-005 5.663640791917708e-5 5716/23165/9183/9883/9972/348995/5701/5688/79023/57122/23636/5684/5903/5347/23225/8021/7283/7443/3320/10762/55706/7175/5579/129401/23511/9631/5501/55869/5710/53371/7321/203068/1457/55746/8481/983/7112/8086/5696/8480/23279/4927/9688/79902 44 Sendai_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 7/603 16/10654 1.3123330838037587e-5 9.412296223572654e-5 6.321520814976627e-5 8454/1147/8945/8517/4790/3551/79155 7 Sendai_virus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 14/603 66/10654 1.4910926500563952e-5 1.0624035131651815e-4 7.13535333233358e-5 7322/5716/3091/5701/5688/2034/5684/7323/9978/112399/5710/7321/7428/5696 14 Sendai_virus R-HSA-1234174 Cellular response to hypoxia 15/603 75/10654 1.5781500804427127e-5 1.106287752421244e-4 7.430090265083147e-5 7322/5716/3091/5701/5688/2034/5684/7323/9978/112399/5710/7321/7428/5696/7422 15 Sendai_virus R-HSA-432720 Lysosome Vesicle Biogenesis 10/603 35/10654 1.58307209825178e-5 1.106287752421244e-4 7.430090265083147e-5 81567/1213/351/9146/162/3312/9829/8673/8907/1174 10 Sendai_virus R-HSA-9613829 Chaperone Mediated Autophagy 8/603 22/10654 1.5833296548965172e-5 1.106287752421244e-4 7.430090265083147e-5 1080/3920/10013/3320/3312/11315/1915/3326 8 Sendai_virus R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 9/603 29/10654 2.0222867877983337e-5 1.4039337122984585e-4 9.429150947156873e-5 4287/4088/2908/847/3066/3065/4087/84676/23410 9 Sendai_virus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 8/603 23/10654 2.308187821697441e-5 1.592208541973458e-4 1.0693649244337459e-4 64127/23118/8517/6885/5599/10454/3654/7189 8 Sendai_virus R-HSA-157118 Signaling by NOTCH 30/603 235/10654 2.3527756075557072e-5 1.607154695360951e-4 1.0794031146371361e-4 5716/10014/8454/8850/3091/5701/10013/5688/23385/5684/1956/4088/8841/4343/9978/9611/55869/5710/3002/3066/3065/7157/83737/5663/207/5696/2683/6772/3280/4609 30 Sendai_virus R-HSA-8878159 Transcriptional regulation by RUNX3 17/603 96/10654 2.3595345942972416e-5 1.607154695360951e-4 1.0794031146371361e-4 5716/8850/5701/5688/7005/5684/4088/10018/1029/5710/7157/5696/10413/6934/3280/4609/4193 17 Sendai_virus R-HSA-71387 Metabolism of carbohydrates 35/603 295/10654 2.4859757357998026e-5 1.6826948261694914e-4 1.1301376535774103e-4 23165/2548/9883/9972/348995/10855/79023/2023/57122/23636/5903/23225/6548/8021/2597/10762/55706/7175/129401/23511/7957/9631/2817/378884/801/4126/53371/55746/8086/2683/8480/23279/4927/9688/79902 35 Sendai_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 18/603 108/10654 3.209121246066096e-5 2.1586821798071936e-4 1.4498220209425774e-4 2353/5743/3091/3320/3662/4843/4985/3312/7184/7157/4170/207/5292/3586/7422/6772/4609/4582 18 Sendai_virus R-HSA-8986944 Transcriptional Regulation by MECP2 13/603 62/10654 3.4191902329798586e-5 2.2857919890846833e-4 1.5351919759513206e-4 8841/3064/4343/5728/9611/801/3066/3065/6446/4233/3654/2289/6515 13 Sendai_virus R-HSA-5357786 TNFR1-induced proapoptotic signaling 6/603 13/10654 3.907062706103645e-5 2.595919577122851e-4 1.7434810009154788e-4 841/27005/8772/7186/1540/8737 6 Sendai_virus R-HSA-199992 trans-Golgi Network Vesicle Budding 14/603 72/10654 4.201877214105684e-5 2.7747762334612535e-4 1.8636053626104154e-4 7037/81567/1213/351/2580/9146/162/2495/3312/9829/8673/8907/5878/1174 14 Sendai_virus R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 8/603 25/10654 4.602826617282335e-5 3.021128016070769e-4 2.0290610478737443e-4 10694/6950/22948/7203/10576/908/10575/10574 8 Sendai_virus R-HSA-432722 Golgi Associated Vesicle Biogenesis 12/603 56/10654 5.443013573074438e-5 3.5510745178551906e-4 2.3849856556718054e-4 7037/81567/1213/2580/162/2495/3312/9829/8673/8907/5878/1174 12 Sendai_virus R-HSA-5357905 Regulation of TNFR1 signaling 9/603 33/10654 6.351569241876975e-5 4.119011670031595e-4 2.766425683036237e-4 1147/841/27005/8517/331/7186/1540/3551/8737 9 Sendai_virus R-HSA-622312 Inflammasomes 7/603 20/10654 7.286410202765843e-5 4.697132291425838e-4 3.154705169242605e-4 7295/351/4790/5970/10910/4791/3326 7 Sendai_virus R-HSA-193704 p75 NTR receptor-mediated signalling 16/603 97/10654 9.915147204817179e-5 6.353907942495269e-4 4.267434891640406e-4 23385/8841/836/4615/4790/5599/10018/3551/3066/3065/5970/4792/5663/3654/7189/8878 16 Sendai_virus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 12/603 60/10654 1.1083228556334814e-4 7.023335190917103e-4 4.7170380686433584e-4 5716/8454/1147/8945/5701/5688/5684/5710/5970/9040/5696/4791 12 Sendai_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 15/603 88/10654 1.1089476617237533e-4 7.023335190917103e-4 4.7170380686433584e-4 5716/3315/3303/5701/5688/5684/8021/7538/3304/3312/5710/207/5696/3184/5580 15 Sendai_virus R-HSA-2562578 TRIF-mediated programmed cell death 5/603 10/10654 1.134553275670045e-4 7.037601439725157e-4 4.726619618846366e-4 841/7099/8772/8737/148022 5 Sendai_virus R-HSA-5602498 MyD88 deficiency (TLR2/4) 5/603 10/10654 1.134553275670045e-4 7.037601439725157e-4 4.726619618846366e-4 10333/7099/4615/7097/7096 5 Sendai_virus R-HSA-350054 Notch-HLH transcription pathway 8/603 28/10654 1.1371932150987096e-4 7.037601439725157e-4 4.726619618846366e-4 10014/8850/10013/8841/9611/55869/3066/3065 8 Sendai_virus R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 8/603 28/10654 1.1371932150987096e-4 7.037601439725157e-4 4.726619618846366e-4 10694/6950/22948/7203/10576/908/10575/10574 8 Sendai_virus R-HSA-6804757 Regulation of TP53 Degradation 9/603 36/10654 1.3310445339928135e-4 8.190461535876233e-4 5.500907733188004e-4 2475/1017/1029/6446/7157/983/207/253260/4193 9 Sendai_virus R-HSA-8951664 Neddylation 28/603 234/10654 1.3758696526022026e-4 8.418456687955849e-4 5.654034671115802e-4 7322/5716/8454/3091/8945/5701/5688/83987/140462/2034/26259/5684/8065/55832/8452/7323/23038/51667/9978/5710/7321/10987/7428/9040/5696/4738/150684/51514 28 Sendai_virus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 34/603 309/10654 1.4699623538918925e-4 8.943647355420896e-4 6.006765148073907e-4 7322/5716/8454/23295/8945/5701/5688/140462/26259/5684/8065/8452/7323/5930/9978/55008/5710/151636/7321/7428/22954/7332/83737/9040/10273/5696/997/63891/10075/7337/9246/84676/51191/3093 34 Sendai_virus R-HSA-5205647 Mitophagy 8/603 29/10654 1.493370181315421e-4 9.035306739467044e-4 6.068325758829497e-4 7416/9474/65018/139341/1457/9140/8878/10452 8 Sendai_virus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 6/603 16/10654 1.5747779580313874e-4 9.474914047488848e-4 6.363576426898765e-4 23118/7099/6885/10454/7189/148022 6 Sendai_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 9/603 37/10654 1.6717668057330062e-4 0.0010002891992314065 6.718178905271924e-4 2475/1017/1029/6446/7157/983/207/253260/4193 9 Sendai_virus R-HSA-9006936 Signaling by TGF-beta family members 16/603 102/10654 1.8228347424147093e-4 0.0010842030509450123 7.281764185284575e-4 867/7046/4088/7323/9611/5501/7321/3065/9040/10273/4087/5499/4738/5500/4609/4221 16 Sendai_virus R-HSA-9013694 Signaling by NOTCH4 14/603 82/10654 1.8320328561674721e-4 0.0010842030509450123 7.281764185284575e-4 5716/8454/8850/5701/5688/23385/5684/4088/9978/5710/5663/207/5696/3280 14 Sendai_virus R-HSA-193692 Regulated proteolysis of p75NTR 5/603 11/10654 1.9833352339001563e-4 0.001154812934577349 7.755996868279614e-4 23385/4790/5970/5663/7189 5 Sendai_virus R-HSA-4755510 SUMOylation of immune response proteins 5/603 11/10654 1.9833352339001563e-4 0.001154812934577349 7.755996868279614e-4 8517/9641/5970/4792/4791 5 Sendai_virus R-HSA-5603041 IRAK4 deficiency (TLR2/4) 5/603 11/10654 1.9833352339001563e-4 0.001154812934577349 7.755996868279614e-4 10333/7099/4615/7097/7096 5 Sendai_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 13/603 73/10654 2.00096033647058e-4 0.0011588449435281486 7.783076794264963e-4 5716/8454/2932/5701/5688/5684/2908/9978/5710/10273/5696/6772/2099 13 Sendai_virus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 9/603 38/10654 2.082160011155417e-4 0.0011994570702560194 8.055837445175774e-4 51741/2064/1956/7422/2099/4609/3329/7528/4869 9 Sendai_virus R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 6/603 17/10654 2.3179780722264198e-4 0.0013212475011690594 8.873810791736598e-4 841/7099/8772/7186/8737/148022 6 Sendai_virus R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 6/603 17/10654 2.3179780722264198e-4 0.0013212475011690594 8.873810791736598e-4 23118/7099/6885/10454/7189/148022 6 Sendai_virus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 11/603 56/10654 2.5180813154701787e-4 0.0014277916568870175 9.589386547202498e-4 5716/3315/3303/5701/5688/5684/3304/3312/5710/5696/3184 11 Sendai_virus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 7/603 24/10654 2.6673810509193714e-4 0.0014995911444798868 0.0010071608891826815 64127/23118/8517/6885/10454/3654/7189 7 Sendai_virus R-HSA-1632852 Macroautophagy 15/603 95/10654 2.6724015778819773e-4 0.0014995911444798868 0.0010071608891826815 2475/55004/5562/128866/7416/9474/65018/3312/139341/1457/57521/55054/9140/8878/10452 15 Sendai_virus R-HSA-69275 G2/M Transition 24/603 196/10654 2.874327579151226e-4 0.0016045859630004007 0.0010776778932140515 5716/8454/55957/1017/22822/8945/5701/5688/5684/5347/7283/3320/984/995/9978/993/5710/203068/7157/8481/983/5696/5500/3326 24 Sendai_virus R-HSA-1251985 Nuclear signaling by ERBB4 8/603 32/10654 3.1477284567871906e-4 0.0017392805707655754 0.0011681419783243548 23118/51741/23385/9611/5663/10413/2099/6285 8 Sendai_virus R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 8/603 32/10654 3.1477284567871906e-4 0.0017392805707655754 0.0011681419783243548 10694/6950/22948/7203/10576/908/10575/10574 8 Sendai_virus R-HSA-111471 Apoptotic factor-mediated response 6/603 18/10654 3.3117529107680536e-4 0.0018206235544983766 0.0012227738505694499 836/331/581/1029/317/54205 6 Sendai_virus R-HSA-453274 Mitotic G2-G2/M phases 24/603 198/10654 3.348116580741127e-4 0.0018313183115871922 0.001229956702441318 5716/8454/55957/1017/22822/8945/5701/5688/5684/5347/7283/3320/984/995/9978/993/5710/203068/7157/8481/983/5696/5500/3326 24 Sendai_virus R-HSA-9609507 Protein localization 21/603 163/10654 3.402543052919632e-4 0.0018517357418653074 0.0012436695316410823 7322/150274/80273/134266/3416/8266/351/10469/3313/9218/7416/4843/847/7323/7321/131118/6449/819/5621/3329/10452 21 Sendai_virus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 11/603 59/10654 4.0560579494913426e-4 0.002196355379649562 0.0014751242332097462 5716/8454/1147/8945/5701/5688/5684/5710/9040/5696/4791 11 Sendai_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 7/603 26/10654 4.591733509863156e-4 0.002471874595184453 0.001660169456453766 7046/4088/5501/10273/4087/5499/5500 7 Sendai_virus R-HSA-8876725 Protein methylation 6/603 19/10654 4.6105140187189245e-4 0.002471874595184453 0.001660169456453766 151194/1938/3312/1915/801/7415 6 Sendai_virus R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 9/603 42/10654 4.6502109317032603e-4 0.002480876078342183 0.00166621506549492 10694/6950/22948/7203/10576/908/1457/10575/10574 9 Sendai_virus R-HSA-5610783 Degradation of GLI2 by the proteasome 11/603 60/10654 4.717794399132912e-4 0.0024923762606150947 0.0016739388599747585 5716/8454/2932/8945/5701/5688/5684/9978/5710/5696/1452 11 Sendai_virus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 11/603 60/10654 4.717794399132912e-4 0.0024923762606150947 0.0016739388599747585 5716/8454/2932/8945/5701/5688/5684/9978/5710/5696/1452 11 Sendai_virus R-HSA-5620920 Cargo trafficking to the periciliary membrane 10/603 51/10654 4.853263079859816e-4 0.0025514970463534855 0.0017136457783255663 10694/79738/6950/22948/7203/10576/8195/10575/6010/6753 10 Sendai_virus R-HSA-1679131 Trafficking and processing of endosomal TLR 5/603 13/10654 5.024372206794034e-4 0.0026160553365182394 0.0017570046532867803 54106/7098/7184/51284/51311 5 Sendai_virus R-HSA-209543 p75NTR recruits signalling complexes 5/603 13/10654 5.024372206794034e-4 0.0026160553365182394 0.0017570046532867803 4615/3551/3654/7189/8878 5 Sendai_virus R-HSA-8943724 Regulation of PTEN gene transcription 11/603 61/10654 5.467504193656008e-4 0.002833161263985386 0.0019028181303532116 2475/10014/55004/1958/8841/23186/6615/3066/3065/7157/57521 11 Sendai_virus R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 7/603 27/10654 5.899864913528397e-4 0.003042644619691074 0.002043512107893796 841/7099/8772/836/7186/8737/148022 7 Sendai_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 13/603 82/10654 6.482711447401842e-4 0.0033273822263204717 0.002234748620680805 5716/8454/2932/8945/5701/5688/5684/9978/5710/3065/5696/1452/6934 13 Sendai_virus R-HSA-5633007 Regulation of TP53 Activity 20/603 160/10654 6.918338025929107e-4 0.0035342264538118975 0.002373670097277564 2475/672/1017/7161/545/4683/5562/580/7159/7994/1029/3066/3065/6446/7157/1457/983/207/253260/4193 20 Sendai_virus R-HSA-3700989 Transcriptional Regulation by TP53 36/603 365/10654 7.878197865575643e-4 0.004005675252778602 0.0026903062639549147 2475/55004/672/7295/2353/1017/2176/7161/545/4683/5562/51499/843/581/580/4343/995/7159/5728/7994/1029/54541/317/3066/3065/6446/7157/10397/1457/57521/983/207/54205/253260/4193/4869 36 Simian_immunodeficiency_virus R-HSA-611105 Respiratory electron transport 5/21 100/10654 1.189853303798117e-6 2.4986919379760454e-4 1.853666199601277e-4 54205/7386/9377/1537/1329 5 Simian_immunodeficiency_virus R-HSA-163200 Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 5/21 123/10654 3.317376002107233e-6 3.4832448022125947e-4 2.5840613069045816e-4 54205/7386/9377/1537/1329 5 Simian_immunodeficiency_virus R-HSA-1428517 The citric acid (TCA) cycle and respiratory electron transport 5/21 174/10654 1.8057655797344004e-5 0.0011198029271537481 8.307309935777179e-4 54205/7386/9377/1537/1329 5 Simian_immunodeficiency_virus R-HSA-5628897 TP53 Regulates Metabolic Genes 4/21 86/10654 2.1329579564833298e-5 0.0011198029271537481 8.307309935777179e-4 4343/54205/9377/1329 4 Simian_virus_40 R-HSA-3700989 Transcriptional Regulation by TP53 305/2223 365/10654 1.2025773494421024e-151 1.6138588029513013e-148 7.215464096652614e-149 23368/6884/1017/23774/6875/834/6118/2176/80010/27161/27113/5563/3725/9891/2963/6917/9134/5434/5440/27165/4436/83990/8621/902/83667/1820/64769/7862/5892/9156/3622/57060/5883/1763/7531/1029/7027/1459/25946/79370/7486/389541/9540/5430/10111/5457/8793/9219/6874/8445/7532/207/10971/5436/55240/9997/22974/133383/2936/9212/57690/204851/7832/4849/6878/1027/58484/4869/3486/5982/51422/7249/404672/27327/898/5931/355/7295/4850/7533/2810/55367/1460/6749/4292/11200/545/472/53632/117584/27244/5441/79813/8794/192670/7534/332/5438/580/8550/5431/7469/11073/9337/5934/639/5435/64065/7316/1869/891/6872/28996/116028/890/80196/2539/84289/1457/54971/4331/10769/983/1026/5433/54205/5366/6790/641/5933/124446/5111/25904/1108/1643/8148/2966/8797/246175/5395/29117/4194/6879/9150/2962/84883/9656/5519/112858/6119/1647/147923/5928/3364/5876/1432/143686/5571/10524/10848/1387/54457/4683/4848/27154/56950/5437/8812/144715/5458/83860/57459/23019/1616/51499/843/2821/2177/28984/10000/6794/2965/5985/54815/51755/2877/2033/995/94241/1874/10128/84126/5728/6009/900/7994/905/2068/54541/5439/1111/192669/3066/3065/2071/7157/1107/8900/55215/5984/91875/8626/6873/6827/5371/23112/208/10498/10542/6233/5527/2968/2475/55004/672/55571/5932/1025/2353/604/7311/63970/7161/839/6881/2967/7029/5562/51616/5518/1386/55835/6880/6908/10419/5325/8851/5300/7156/581/5983/4343/6117/11198/50484/5600/7159/57472/904/6883/3276/144455/7936/85456/6829/79733/29883/26523/51497/5564/7874/51230/6882/5052/637/317/5565/1020/138474/133746/5884/5810/53615/10397/1022/8795/5432/665/57521/26155/26013/8178/5875/83695/10919/6877/7529/7296/7314/4193/5515/25920/1263/27166/5516 305 Simian_virus_40 R-HSA-69620 Cell Cycle Checkpoints 225/2223 293/10654 1.6547635404230975e-96 1.1103463356238985e-93 4.964290621269293e-94 5718/1017/220134/4172/6118/5689/5905/80010/55839/11130/79682/9134/5684/5903/10403/5720/83990/11065/54908/8318/6249/55143/5682/9156/57060/55055/5883/25936/5525/9735/1763/7531/51512/1029/80776/25946/1783/1058/5700/7486/122706/7321/5707/991/401541/79019/5526/10111/7532/10971/348235/80152/5690/9212/1063/51588/51720/8379/5717/1027/3619/5982/9491/23198/63967/79172/898/7533/2810/147841/348995/23421/4173/11200/143471/545/55920/79023/5706/9133/472/57122/5705/79980/64105/10197/7336/6232/7534/332/580/1780/8881/11073/29086/23122/5528/5048/1781/7316/10213/5709/4174/891/993/5695/5501/116028/890/57405/8655/4085/983/1026/84515/641/5714/4171/23279/55166/9861/79902/4194/3796/5715/54821/9656/5519/4998/6119/5711/9183/3364/81565/7341/5701/10524/2491/5688/4683/1062/699/5687/144715/5685/5683/5698/5708/5692/22919/5985/5686/5713/990/1060/91687/995/165918/79003/84126/5699/5529/4175/5710/51143/1111/5702/7157/8900/5984/83540/5719/8924/11004/5704/6233/5527/55388/5716/701/672/7514/5932/7158/7311/9184/9025/79184/5518/54820/5347/57551/7156/84643/5983/6117/29882/6396/7334/5694/23332/7465/25909/51230/64946/9793/10726/5884/5810/81930/55746/5693/5721/140735/5696/83695/5691/4176/7529/7314/996/4193/5515/1778/5516 225 Simian_virus_40 R-HSA-5633007 Regulation of TP53 Activity 146/2223 160/10654 1.943578691191554e-83 8.694275345263551e-81 3.887157382383108e-81 23368/6884/1017/23774/6875/6118/80010/5563/9891/83990/64769/7862/9156/3622/5883/1763/1029/1459/25946/7486/10111/5457/9219/6874/8445/207/22974/133383/9212/204851/6878/5982/51422/5931/1460/6749/11200/545/472/53632/117584/79813/580/8550/11073/639/7316/6872/28996/116028/890/80196/84289/1457/54971/983/6790/641/1108/8148/29117/4194/6879/5519/112858/6119/5928/3364/1432/5571/10524/10848/54457/4683/27154/56950/144715/5458/83860/57459/1616/10000/6794/5985/54815/2033/94241/84126/900/7994/1111/3066/3065/7157/1107/8900/5984/91875/8626/6873/5371/208/6233/5527/2475/672/5932/7311/7161/6881/5562/51616/5518/6880/6908/10419/8851/5300/7156/5983/6117/11198/5600/7159/6883/5564/7874/51230/6882/5565/1020/138474/133746/5884/5810/53615/26155/26013/83695/10919/6877/7314/4193/5515/1263/5516 146 Simian_virus_40 R-HSA-449147 Signaling by Interleukins 277/2223 461/10654 6.600888049711615e-79 2.2145979406782466e-76 9.901332074567421e-77 729230/3605/3557/7124/1147/5718/2308/834/1052/5689/3725/7291/8945/596/5055/5684/5601/3562/351/2208/3592/5290/5720/3566/1437/4790/6627/6885/6597/5606/2309/5682/90865/4215/64109/9049/3561/3587/5700/6351/3578/122706/7184/5707/27250/9180/3593/207/6775/50616/3911/5292/3684/9021/7422/5690/3553/2625/1230/5594/9446/8878/3595/4582/5717/2919/9491/23198/6500/5908/5743/3091/3568/941/143471/4318/6367/5706/4312/3383/5705/301/11009/6097/10197/6349/8517/6657/1438/6778/53833/3576/4615/3581/7534/3313/332/3662/3597/6776/5528/3688/2357/1436/4313/7316/3565/10213/5709/6175/9978/2920/3560/5695/3976/6352/50615/3185/6774/4314/1435/5970/4792/1441/1026/6348/1440/4793/3627/7133/5714/3606/6772/8651/4609/3146/9861/149233/6364/5715/5519/64127/8503/5711/7132/4988/5598/3552/1432/4208/5701/5688/79923/3567/5687/6950/4067/3558/3717/23291/4088/598/2247/836/5685/5683/5698/5708/3320/5602/29949/5692/5686/5713/2335/3656/595/6195/5699/57162/9466/5771/5710/3458/3181/10454/6288/5702/998/7157/6648/116379/5478/942/5719/3654/3563/7189/163702/27177/112744/6285/5609/5704/6233/2885/1398/58985/3716/5716/85480/1385/2353/604/6196/7311/3594/53832/6363/2939/6347/3575/7076/5518/302/1386/6382/7040/6935/3687/3588/51561/3570/6197/5599/5600/5784/7431/4282/6777/7334/6356/3600/5694/3977/3312/1399/3559/3574/3551/246778/6773/7850/7297/3569/3162/57161/4170/5693/1234/5721/5696/3586/5691/5724/3554/5034/51231/4692/829/7314/3572/3596/5595/5515/59067/5516 277 Simian_virus_40 R-HSA-453279 Mitotic G1-G1/S phases 136/2223 149/10654 9.34935874215082e-78 2.50936788639328e-75 1.1219230490580984e-75 5718/1017/4172/6118/5689/25/894/9134/1019/5684/5720/4605/902/8318/5682/1029/7027/5700/5707/207/5690/5717/1027/9491/6500/7153/898/54107/5925/4173/5706/5705/10197/286826/91768/5934/5557/7316/10213/5709/5422/1869/4174/891/1875/993/5695/890/1876/4331/983/1026/84515/5933/5714/5111/5426/6714/4171/4609/1871/9861/51053/1031/5715/5519/4998/6119/5711/5928/5701/5688/5687/91750/5427/4067/3717/6502/5685/5683/5698/5708/10000/5692/5686/5713/990/1021/1874/595/5699/4175/5710/81620/5702/3065/5520/8900/896/5719/208/1870/5704/6233/7298/55388/5716/1032/28227/55957/1030/7311/7029/5518/23649/6117/1719/5694/7465/1163/5558/1022/1859/5693/5721/5696/7083/132660/5691/1028/4176/7314/5515/6241/5516/56655 136 Simian_virus_40 R-HSA-68882 Mitotic Anaphase 162/2223 201/10654 6.093873733790388e-75 1.3629964251244502e-72 6.093873733790389e-73 4000/5718/220134/5689/5905/55839/11130/79682/5684/5903/10403/5720/11065/54908/6249/55143/5682/55055/25936/5525/9735/80776/1783/1058/5700/122706/7321/5707/991/401541/79019/5526/51807/348235/80152/5690/9212/1063/8379/5717/3619/9491/23198/79172/10274/147841/23244/7277/348995/23421/143471/55920/79023/5706/57122/5705/79980/64105/10735/10197/6232/332/7443/23047/1780/8881/23122/5885/5528/5048/1781/7316/10213/5709/5695/5501/57405/8655/4085/5714/23279/55166/9861/79902/3796/5715/54821/5519/5711/9183/81565/5701/2491/5688/1062/699/5687/7846/5685/5683/7444/5698/5708/5692/22919/5686/5713/1060/91687/79003/8243/9126/5699/5529/5710/51143/5702/5520/2010/83540/5719/11004/9232/5704/6233/5527/9700/5716/701/7514/7311/9184/5518/10383/54820/5347/57551/113130/84790/84643/29882/6396/5694/23332/25909/64946/9793/10726/81930/55746/7112/5693/5721/140735/5696/7280/5691/7314/996/5515/1778/5516 162 Simian_virus_40 R-HSA-2467813 Separation of Sister Chromatids 156/2223 190/10654 2.1351569866356377e-74 4.09340096580718e-72 1.8301345599734042e-72 5718/220134/5689/5905/55839/11130/79682/5684/5903/10403/5720/11065/54908/6249/55143/5682/55055/25936/5525/9735/80776/1783/1058/5700/122706/7321/5707/991/401541/79019/5526/51807/348235/80152/5690/9212/1063/8379/5717/3619/9491/23198/79172/10274/147841/23244/7277/348995/23421/143471/55920/79023/5706/57122/5705/79980/64105/10735/10197/6232/332/23047/1780/8881/23122/5885/5528/5048/1781/7316/10213/5709/5695/5501/57405/8655/4085/5714/23279/55166/9861/79902/3796/5715/54821/5519/5711/9183/81565/5701/2491/5688/1062/699/5687/7846/5685/5683/5698/5708/5692/22919/5686/5713/1060/91687/79003/8243/9126/5699/5529/5710/51143/5702/83540/5719/11004/9232/5704/6233/5527/9700/5716/701/7514/7311/9184/5518/10383/54820/5347/57551/113130/84790/84643/29882/6396/5694/23332/25909/64946/9793/10726/81930/55746/5693/5721/140735/5696/7280/5691/7314/996/5515/1778/5516 156 Simian_virus_40 R-HSA-2555396 Mitotic Metaphase and Anaphase 162/2223 202/10654 2.47460830242001e-74 4.1511554273095666e-72 1.8559562268150076e-72 4000/5718/220134/5689/5905/55839/11130/79682/5684/5903/10403/5720/11065/54908/6249/55143/5682/55055/25936/5525/9735/80776/1783/1058/5700/122706/7321/5707/991/401541/79019/5526/51807/348235/80152/5690/9212/1063/8379/5717/3619/9491/23198/79172/10274/147841/23244/7277/348995/23421/143471/55920/79023/5706/57122/5705/79980/64105/10735/10197/6232/332/7443/23047/1780/8881/23122/5885/5528/5048/1781/7316/10213/5709/5695/5501/57405/8655/4085/5714/23279/55166/9861/79902/3796/5715/54821/5519/5711/9183/81565/5701/2491/5688/1062/699/5687/7846/5685/5683/7444/5698/5708/5692/22919/5686/5713/1060/91687/79003/8243/9126/5699/5529/5710/51143/5702/5520/2010/83540/5719/11004/9232/5704/6233/5527/9700/5716/701/7514/7311/9184/5518/10383/54820/5347/57551/113130/84790/84643/29882/6396/5694/23332/25909/64946/9793/10726/81930/55746/7112/5693/5721/140735/5696/7280/5691/7314/996/5515/1778/5516 162 Simian_virus_40 R-HSA-5663205 Infectious disease 235/2223 383/10654 3.671169524200778e-69 5.474121668308271e-67 2.4474463494671854e-67 6158/6884/5718/23165/3303/6875/5689/5905/6138/8945/6144/2963/3837/3838/2237/6917/6203/5434/5440/5684/5903/9349/4736/7852/5720/902/6206/6194/6191/55706/7175/162/6128/5606/5682/51121/6132/9631/1499/1938/3159/6147/6129/6217/4057/5700/122706/5707/5430/6874/6222/5436/6152/5690/6136/7518/7520/6878/6125/5717/4869/9491/23198/6500/404672/6749/6154/51065/348995/6141/9636/10015/143471/6202/79023/5706/57122/5705/5441/23636/10197/6232/5438/3978/3981/10762/5431/6160/7469/23511/5435/7316/6155/10213/5709/6175/9978/293/6218/5695/6872/53371/292/567/4233/4331/5433/4836/9397/6209/5714/6714/23279/4927/6231/9688/6229/8148/2966/9861/79902/6130/6879/9150/5715/2962/6142/3840/5711/6204/9883/5701/5688/54457/5437/8812/5687/83860/23225/999/5685/5683/5698/5708/3320/5692/2965/5686/128866/5713/140801/6156/5699/905/6143/5710/2068/6181/5439/6124/5702/2071/5901/6207/8086/5478/6873/5719/6827/5609/5704/6233/2885/3326/2968/5716/7514/1025/9844/7311/6223/9972/6881/2967/51616/1213/5610/6880/6908/1211/3921/6188/6189/8021/7040/7251/11198/6396/6135/6201/129401/904/6883/5694/7936/3304/6829/1104/51497/2547/9045/6882/6187/138474/1022/5432/55746/6168/5693/6208/1234/10254/5721/6137/5696/8178/5691/8480/6122/6877/7296/940/7314/25920/6230 235 Simian_virus_40 R-HSA-2262752 Cellular responses to stress 270/2223 479/10654 2.3308002589008224e-68 3.1279339474449033e-66 1.3984801553404936e-66 1912/5718/1017/23165/3303/7014/6118/5689/3725/6782/25913/9134/1019/5684/5903/5601/5720/11065/573/2876/83667/4790/55706/7175/5241/5606/5682/9631/3159/112399/7531/7290/1029/7027/1915/1783/5700/122706/116835/7321/5707/2146/389541/10111/8535/51807/2878/6045/7422/5690/2936/57690/5594/3308/5717/1027/9491/23198/27327/80012/898/10049/5931/7295/10294/5925/3091/7013/7277/348995/1051/1410/10013/143471/50488/545/79023/5706/472/27244/57122/5705/23636/79813/10197/3337/192670/3576/3313/1780/10762/8550/8881/29855/847/23511/1781/7316/10213/5709/9978/2114/1869/5695/890/3305/53371/8655/6774/5970/1026/1911/9532/54205/832/26277/6667/5714/23279/4927/9688/7415/1871/9861/79902/4194/1031/5715/2882/6119/5711/26353/5598/9883/3552/5928/10370/1432/2932/5701/10524/5688/1387/84733/4683/5687/57805/7846/259217/23225/3310/2908/5685/5683/3309/5698/5708/3320/5602/5692/65057/5686/5713/2877/2033/23512/1021/7266/57332/6195/5699/6009/5710/6767/25842/51143/3301/7428/5702/192669/10540/493869/9531/7157/8900/6648/8086/23135/5719/22824/8091/23112/5609/8131/1870/10542/5704/6233/2056/3326/2475/5716/55004/1032/3306/2353/1030/51343/6196/7311/367/9972/7029/57634/10383/23411/84790/8021/9529/4343/8726/55662/6117/6197/29882/5599/6396/648/129401/5600/5694/3304/3312/201163/23466/4217/26523/3456/5052/2113/405/3569/3297/57521/55746/5693/5721/257202/140735/5696/7280/2288/5691/5034/8480/10919/768/10728/829/2880/7296/7314/23523/996/51182/6015/5595/4193/2950/1778 270 Simian_virus_40 R-HSA-69242 S Phase 135/2223 161/10654 1.1302154913958375e-66 1.3788628995029218e-64 6.1648117712500235e-65 5718/1017/4172/6118/5689/2237/9134/1019/5684/994/5720/11065/902/8318/5682/1763/7027/5700/122706/7321/5707/57804/207/5690/5717/1027/5982/9491/23198/6500/898/10274/54107/5925/23244/4173/143471/5706/5705/10735/10197/286826/23047/3978/91768/8881/5934/5885/5557/7316/10213/5709/5422/9978/1869/4174/1875/993/5695/890/4331/1026/5425/84515/5714/5111/5426/4171/4609/9861/5715/4998/6119/5711/5928/2932/5701/5688/5687/91750/5427/6502/5685/5683/5698/5708/10000/5692/5985/5686/5713/990/1874/8243/9126/595/5699/4175/5710/81620/5702/8900/5984/5719/208/5704/6233/5716/55957/51343/7311/7029/51659/113130/23649/5983/6117/29882/5981/5694/10714/7465/1163/5558/5424/1022/5693/5721/5696/132660/5691/4176/7314/996/56655 135 Simian_virus_40 R-HSA-69206 G1/S Transition 118/2223 131/10654 6.571104155908976e-66 7.348684814358205e-64 3.285552077954488e-64 5718/1017/4172/6118/5689/9134/1019/5684/5720/902/8318/5682/7027/5700/5707/207/5690/5717/1027/9491/6500/898/54107/5925/4173/5706/5705/10197/286826/91768/5934/5557/7316/10213/5709/5422/1869/4174/891/1875/993/5695/890/1876/4331/983/1026/84515/5933/5714/5111/5426/4171/4609/9861/51053/5715/5519/4998/6119/5711/5928/5701/5688/5687/91750/5427/6502/5685/5683/5698/5708/10000/5692/5686/5713/990/1874/595/5699/4175/5710/81620/5702/3065/8900/5719/208/5704/6233/7298/55388/5716/28227/55957/7311/7029/5518/23649/6117/1719/5694/7465/1163/5558/1022/5693/5721/5696/7083/132660/5691/4176/7314/5515/6241/5516/56655 118 Simian_virus_40 R-HSA-8953897 Cellular responses to external stimuli 271/2223 493/10654 1.9585308452607126e-65 2.0218064571845201e-63 9.039373131972519e-64 1912/5718/1017/23165/3303/7014/6118/5689/3725/6782/25913/9134/1019/5684/5903/5601/5720/11065/573/2876/83667/4790/55706/7175/5241/5606/5682/9631/3159/112399/7531/7290/1029/7027/1915/1783/5700/122706/116835/7321/5707/2146/389541/10111/8535/51807/2878/6045/7422/5690/2936/57690/5594/3308/5717/1027/9491/23198/27327/80012/898/10049/5931/7295/10294/5925/3091/7013/7277/348995/1051/1410/10013/143471/50488/545/79023/5706/472/27244/57122/5705/23636/79813/10197/3337/192670/3576/3313/1780/10762/8550/8881/29855/847/23511/1781/7316/10213/5709/9978/2114/1869/1465/5695/890/3305/53371/8655/6774/5970/1026/1911/9532/54205/832/26277/6667/5714/23279/4927/9688/7415/1871/9861/79902/4194/1031/5715/2882/6119/5711/26353/5598/9883/3552/5928/10370/1432/2932/5701/10524/5688/1387/84733/4683/5687/57805/7846/259217/23225/3310/2908/5685/5683/3309/5698/5708/3320/5602/5692/65057/5686/5713/2877/2033/23512/1021/7266/57332/6195/5699/6009/5710/6767/25842/51143/3301/7428/5702/192669/10540/493869/9531/7157/8900/6648/8086/23135/5719/22824/8091/23112/5609/8131/1870/10542/5704/6233/2056/3326/2475/5716/55004/1032/3306/2353/1030/51343/6196/7311/367/9972/7029/57634/10383/23411/84790/8021/9529/4343/8726/55662/6117/6197/29882/5599/6396/648/129401/5600/5694/3304/3312/201163/23466/4217/26523/3456/5052/2113/405/3569/3297/57521/55746/5693/5721/257202/140735/5696/7280/2288/5691/5034/8480/10919/768/10728/829/2880/7296/7314/23523/996/51182/6015/5595/4193/2950/1778 271 Simian_virus_40 R-HSA-73894 DNA Repair 209/2223 334/10654 1.5429507494982147e-63 1.4790285041618602e-61 6.612646069278063e-62 9318/8467/11284/51750/1017/7014/6118/2176/80010/54962/124739/25/25913/3838/2237/6917/5434/5440/5893/4436/83990/902/7516/5888/5892/9156/2074/5883/1763/322/328/7486/5430/10111/57804/4913/5436/7320/51588/7518/7520/51720/675/2956/7515/5982/63967/404672/54107/7013/5531/51548/4292/9636/11200/545/472/6613/5441/7507/7706/80198/7336/86/5438/3978/3981/580/5431/11073/2072/5591/29086/8450/5435/7316/2140/9978/11201/116028/2070/890/197342/9031/6996/4331/5425/5433/26277/641/5111/5426/9100/1643/10635/10459/2966/7415/5395/7517/64421/9656/6119/84464/51455/3364/22976/7341/10524/4683/5437/10401/5427/144715/1161/5889/55775/9937/2177/1642/5429/2965/5985/65057/25898/2033/165918/29089/84126/142/8914/7398/2068/5439/1111/10987/2071/7157/9682/8900/55215/5984/23514/1069/4595/7329/4255/9246/79728/8924/57599/6233/2067/51426/2873/2968/146956/672/5932/7158/7311/2138/6047/9025/7318/4968/2967/79184/6612/23030/3980/55247/60/5536/7156/5890/5887/5983/6117/5599/7334/5981/10038/10714/7874/2547/5884/5810/5424/79840/1022/5432/2139/348654/8178/83695/4437/5886/55183/5980/57697/7508/7314/51514/51138/8451/8554/7528/56655 209 Simian_virus_40 R-HSA-6807070 PTEN Regulation 121/2223 140/10654 6.568975626363784e-63 5.877043527053466e-61 2.627590250545514e-61 1912/5718/5689/27161/3725/6591/5684/8841/5720/5682/5468/1822/23186/1459/5700/122706/5707/2146/389541/5978/9112/9219/8535/10273/207/51564/6045/5690/57690/5594/84232/5717/9491/23198/27327/80012/5931/1460/143471/5706/5705/10197/192670/7316/10213/5709/5695/1457/1911/5714/1108/57167/2122/9861/7101/10014/5715/5711/1958/5928/5701/5688/84733/5687/57459/5685/5683/5698/5708/10000/5692/54815/5686/5713/23512/57332/5728/5699/6009/2444/5710/6615/5702/192669/3066/3065/7157/1107/23028/5719/5987/5371/23112/208/10542/5704/6233/2475/5716/55004/57504/7311/1386/331/4343/8726/648/5694/23466/26523/7874/53615/57521/5693/5721/5696/23608/5691/7314/6015/5595 121 Simian_virus_40 R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 91/2223 92/10654 1.9552845959723637e-61 1.63999495487182e-59 7.332317234896364e-60 6884/1017/6875/6118/80010/5563/9891/83990/9156/5883/1763/1459/7486/10111/6874/8445/22974/9212/204851/6878/5982/51422/1460/6749/11200/545/472/53632/580/8550/11073/7316/6872/28996/116028/890/1457/6790/641/8148/4194/6879/112858/6119/3364/1432/5571/10524/54457/4683/144715/83860/6794/5985/94241/84126/1111/7157/8900/5984/6873/6233/672/5932/7311/6881/5562/51616/6880/6908/8851/5300/7156/5983/6117/11198/5600/6883/5564/6882/5565/1020/138474/5884/5810/26155/83695/6877/7314/4193/1263 91 Simian_virus_40 R-HSA-68886 M Phase 228/2223 395/10654 4.546462158232056e-60 3.589030715498482e-58 1.6046337029054316e-58 10844/4000/115106/5718/23165/220134/5689/5905/55839/11130/22995/79682/5684/5903/10403/5720/11065/54908/55706/7175/6249/55143/5579/5682/64151/22981/9631/55055/25936/5525/9735/7531/80776/1459/1783/1058/5700/122706/7321/5707/991/91754/401541/203068/79019/5526/51807/7532/1454/348235/2801/80152/5690/5578/9212/5594/1063/8379/5717/3619/9491/23198/79172/10274/5861/5925/1460/147841/23244/7277/348995/23421/143471/55920/79023/5706/9133/57122/5705/23636/79980/64105/10735/23310/10197/6232/332/7443/23047/1780/10762/8881/10051/23122/5885/23511/5528/5048/1781/7316/10213/5709/891/5695/5501/53371/26003/57405/8655/4085/1457/983/5714/23279/4927/9688/55166/9861/79902/3796/8615/5715/54821/5519/81876/5711/9183/9883/81565/5701/2491/5688/10112/1062/699/5687/7846/23225/5685/7283/5683/7444/5698/5708/3320/5692/22919/5686/5713/80097/1060/91687/79003/8243/9126/5699/23397/5529/5710/51143/9918/5702/10540/5520/10733/1069/8086/2010/83540/5719/79648/4751/11004/9232/5704/6233/5527/9700/5716/701/7514/7311/9184/54930/9972/5518/10383/55835/54820/5347/57551/113130/54892/84790/8021/84643/9493/29882/6396/129401/9662/5694/23332/1453/25909/64946/9793/10726/6418/81930/55746/8481/7112/5693/5721/140735/5696/10592/7280/5691/29781/8480/7314/996/5595/5515/1778/5516 228 Simian_virus_40 R-HSA-162906 HIV Infection 160/2223 233/10654 6.765454719135613e-57 5.044022351711107e-55 2.2551515730452044e-55 6884/5718/23165/6875/5689/5905/8945/2963/3837/2237/6917/5434/5440/5684/5903/7852/5720/902/55706/7175/162/5682/9631/3159/5700/122706/5707/5430/6874/5436/5690/7518/7520/6878/5717/4869/9491/23198/6500/404672/6749/348995/10015/143471/79023/5706/57122/5705/5441/23636/10197/5438/3978/3981/10762/5431/7469/23511/5435/7316/10213/5709/9978/293/5695/6872/53371/292/567/4331/5433/4836/9397/5714/23279/4927/9688/8148/2966/9861/79902/6879/9150/5715/2962/5711/9883/5701/5688/54457/5437/8812/5687/83860/23225/5685/5683/5698/5708/5692/2965/5686/128866/5713/5699/905/5710/2068/5439/5702/2071/5901/8086/5478/6873/5719/6827/5704/6233/2968/5716/7514/1025/9844/7311/9972/6881/2967/51616/6880/6908/8021/7251/11198/6396/129401/904/6883/5694/7936/6829/1104/51497/2547/6882/138474/1022/5432/55746/5693/1234/5721/5696/8178/5691/8480/6877/940/7314/25920 160 Simian_virus_40 R-HSA-1257604 PIP3 activates AKT signaling 172/2223 264/10654 5.599090070498307e-56 3.954725723478278e-54 1.7681337064731497e-54 1912/1147/5718/2308/5689/27161/3725/6591/5684/8841/5290/5720/2309/5682/90865/5468/5525/1822/23186/1459/842/5700/3815/122706/5707/2146/389541/5978/5526/9112/9219/8535/10273/207/51564/6045/5690/57690/5594/4303/84232/5717/1027/9491/7249/23198/27327/80012/930/5931/1460/941/143471/5706/2064/5705/10197/192670/4615/5528/2100/7316/10213/5709/1950/5695/1457/4233/1026/1911/5714/6714/2099/1108/57167/2122/9861/7101/10014/5715/5519/8503/5711/1958/5928/2932/5701/5688/84733/5159/5687/57459/2247/5685/3164/5683/5698/5708/10000/5692/54815/5686/5713/23512/57332/5728/5699/6009/5529/2444/5710/6615/2264/3630/5702/192669/3066/3065/7157/1107/2066/23028/942/5719/5987/3654/7189/5371/23112/208/10542/5704/6233/5527/2885/2475/5716/55004/2246/1385/57504/7311/5154/5518/5155/1386/2252/1956/331/4343/8726/648/2549/5694/23466/26523/7874/53615/57521/5693/5721/5696/23608/5691/5156/940/7314/6015/5595/4193/5515/5516 172 Simian_virus_40 R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 81/2223 85/10654 1.921561460281161e-50 1.289367739848659e-48 5.764684380843483e-49 5718/1017/5689/9134/1019/5684/994/5720/902/5682/7027/5700/5707/207/5690/5717/1027/9491/6500/898/5925/5706/5705/10197/286826/91768/5934/7316/10213/5709/1869/1875/993/5695/890/4331/1026/5714/4609/9861/5715/5711/5928/5701/5688/5687/91750/6502/5685/5683/5698/5708/10000/5692/5686/5713/1874/595/5699/5710/5702/8900/5719/208/5704/6233/5716/55957/51343/7311/7029/5694/7465/1163/1022/5693/5721/5696/132660/5691/7314 81 Simian_virus_40 R-HSA-2500257 Resolution of Sister Chromatid Cohesion 104/2223 126/10654 3.688779583164281e-50 2.3573058098126024e-48 1.053937023761223e-48 220134/5905/55839/11130/79682/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/401541/79019/5526/51807/348235/80152/9212/1063/8379/3619/79172/10274/147841/23244/7277/348995/23421/55920/79023/9133/57122/79980/64105/10735/6232/332/23047/1780/23122/5885/5528/5048/1781/891/5501/57405/8655/4085/983/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/7846/22919/1060/91687/79003/8243/9126/5529/51143/83540/11004/5527/701/7514/9184/5518/10383/54820/5347/57551/113130/84790/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/7280/5515/1778/5516 104 Simian_virus_40 R-HSA-141424 Amplification of signal from the kinetochores 87/2223 96/10654 2.7774582422144246e-49 1.6205865048051123e-47 7.24554324055937e-48 220134/5905/55839/11130/79682/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/401541/79019/5526/348235/80152/9212/1063/8379/3619/79172/147841/348995/23421/55920/79023/57122/79980/64105/6232/332/1780/23122/5528/5048/1781/5501/57405/8655/4085/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/22919/1060/91687/79003/5529/51143/83540/11004/5527/701/7514/9184/5518/54820/5347/57551/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/5515/1778/5516 87 Simian_virus_40 R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 87/2223 96/10654 2.7774582422144246e-49 1.6205865048051123e-47 7.24554324055937e-48 220134/5905/55839/11130/79682/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/401541/79019/5526/348235/80152/9212/1063/8379/3619/79172/147841/348995/23421/55920/79023/57122/79980/64105/6232/332/1780/23122/5528/5048/1781/5501/57405/8655/4085/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/22919/1060/91687/79003/5529/51143/83540/11004/5527/701/7514/9184/5518/54820/5347/57551/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/5515/1778/5516 87 Simian_virus_40 R-HSA-69202 Cyclin E associated events during G1/S transition 79/2223 83/10654 4.242440564708064e-49 2.372231349099259e-47 1.0606101411770159e-47 5718/1017/5689/9134/1019/5684/5720/902/5682/7027/5700/5707/207/5690/5717/1027/9491/6500/898/5925/5706/5705/10197/286826/91768/5934/7316/10213/5709/1869/1875/993/5695/890/4331/1026/5714/4609/9861/5715/5711/5928/5701/5688/5687/91750/6502/5685/5683/5698/5708/10000/5692/5686/5713/1874/595/5699/5710/5702/8900/5719/208/5704/6233/5716/55957/7311/7029/5694/7465/1163/1022/5693/5721/5696/132660/5691/7314 79 Simian_virus_40 R-HSA-69306 DNA Replication 103/2223 127/10654 2.81193693910583e-48 1.5094477489120095e-46 6.748648653853992e-47 5718/1017/4172/6118/5689/2237/9134/5684/5720/11065/8318/5682/1763/5700/122706/7321/5707/57804/5690/5717/5982/9491/23198/6500/898/54107/4173/143471/5706/5705/10197/3978/8881/5557/7316/10213/5709/5422/9978/1869/4174/5695/890/5425/84515/5714/5111/5426/4171/1871/9861/51053/5715/4998/6119/5711/5701/5688/5687/5427/6502/5685/5683/5698/5708/5692/5985/5686/5713/990/5699/4175/5710/81620/5702/8900/5984/5719/1870/5704/6233/55388/5716/51343/7311/51659/23649/5983/6117/29882/5981/5694/10714/5558/5424/5693/5721/5696/5691/4176/7314/996/56655 103 Simian_virus_40 R-HSA-69239 Synthesis of DNA 98/2223 119/10654 3.898109942923423e-47 2.0120244397704746e-45 8.995638329823284e-46 5718/1017/4172/6118/5689/2237/9134/5684/5720/11065/8318/5682/1763/5700/122706/7321/5707/57804/5690/5717/5982/9491/23198/6500/898/54107/4173/143471/5706/5705/10197/3978/8881/5557/7316/10213/5709/5422/9978/4174/5695/890/5425/84515/5714/5111/5426/4171/9861/5715/4998/6119/5711/5701/5688/5687/5427/6502/5685/5683/5698/5708/5692/5985/5686/5713/990/5699/4175/5710/81620/5702/8900/5984/5719/5704/6233/5716/51343/7311/51659/23649/5983/6117/29882/5981/5694/10714/5558/5424/5693/5721/5696/5691/4176/7314/996/56655 98 Simian_virus_40 R-HSA-69481 G2/M Checkpoints 121/2223 168/10654 1.1852122825063987e-46 5.890944011568841e-45 2.6338050722364416e-45 5718/1017/4172/6118/5689/80010/5684/5720/83990/8318/5682/9156/5883/1763/7531/51512/5700/7486/122706/5707/10111/7532/10971/5690/51588/51720/5717/5982/9491/23198/63967/7533/2810/4173/11200/143471/545/5706/9133/472/5705/10197/7336/7534/580/11073/29086/7316/10213/5709/4174/891/993/5695/116028/983/84515/641/5714/4171/9861/5715/9656/4998/6119/5711/3364/7341/5701/10524/5688/4683/5687/144715/5685/5683/5698/5708/5692/5985/5686/5713/990/995/165918/84126/5699/4175/5710/1111/5702/7157/5984/5719/8924/5704/6233/55388/5716/672/5932/7158/7311/9025/79184/7156/5983/6117/7334/5694/7465/5884/5810/5693/5721/5696/83695/5691/4176/7529/7314 121 Simian_virus_40 R-HSA-5693532 DNA Double-Strand Break Repair 120/2223 166/10654 1.4964469661197104e-46 7.172256530473756e-45 3.206672070256522e-45 8467/51750/1017/6118/80010/54962/25/3838/2237/5893/83990/7516/5888/5892/9156/5883/1763/322/7486/10111/57804/51588/7518/7520/51720/675/7515/5982/63967/54107/5531/51548/11200/545/472/6613/80198/7336/3981/580/11073/2072/5591/29086/7316/2140/116028/2070/890/197342/9031/5425/641/5111/5426/10635/7517/64421/9656/6119/84464/3364/22976/7341/10524/4683/5427/144715/5889/55775/5429/5985/165918/84126/142/8914/1111/7157/9682/8900/5984/23514/7329/79728/8924/6233/2067/51426/146956/672/5932/7158/7311/2138/6047/9025/79184/23030/3980/5536/7156/5890/5983/6117/5599/7334/5981/10038/10714/2547/5884/5810/5424/79840/2139/348654/83695/55183/7314/56655 120 Simian_virus_40 R-HSA-9006925 Intracellular signaling by second messengers 176/2223 305/10654 3.043954291849803e-46 1.4086160895387709e-44 6.297836465896145e-45 1912/1147/5718/2308/5689/27161/3725/6591/3838/5684/8841/5290/5720/5335/2309/5682/90865/5468/5525/1822/23186/1459/842/5700/3815/122706/5707/2146/389541/5978/5526/9112/9219/8535/10273/207/51564/6045/5690/5578/57690/5594/4303/84232/5717/1027/9491/7249/23198/27327/80012/930/5931/1460/941/143471/5706/2064/5705/10197/192670/4615/5528/2100/7316/10213/5709/1950/5695/1457/4233/1026/1911/5714/6714/2099/1108/57167/2122/9861/7101/10014/5715/5519/8503/5711/1958/5928/2932/5701/5688/84733/5159/5687/57459/2247/5685/3164/5683/5698/5708/10000/5692/54815/5686/5713/23512/57332/5728/5699/6009/5529/2444/5710/6615/2264/3630/5702/192669/3066/3065/7157/1107/2066/23028/942/5719/5987/3654/7189/5371/23112/208/10542/5704/6233/5527/2885/5580/2475/5716/55004/2246/1385/57504/7311/5154/5518/5155/1386/2252/1956/331/4343/8726/648/2549/5694/23466/26523/7874/53615/57521/5693/5721/5696/23608/5691/5156/940/7314/6015/5595/4193/5515/5516 176 Simian_virus_40 R-HSA-2990846 SUMOylation 128/2223 188/10654 5.980196547429992e-45 2.67514125555035e-43 1.1960393094859985e-43 1912/10054/23165/7020/23468/7150/5905/5893/6670/5903/7068/29843/55706/7175/1487/55143/5241/83746/3622/9631/5468/7021/1029/7486/1788/9112/8535/51564/1786/6045/9212/51588/7518/3619/4869/3090/80012/7153/10274/348995/79023/6613/57122/23636/10735/8517/332/10762/5465/5885/23511/10210/28996/53371/1655/5970/4792/3190/6996/9612/8856/1911/6790/641/23137/6672/5111/2099/23279/4927/9688/79902/9656/9883/7341/1387/84733/10401/1616/23225/2908/10055/2033/23512/165918/8243/9126/57332/7022/142/7428/3066/3065/7157/1107/1069/8086/7329/5987/5371/8924/672/115426/7158/10155/367/9972/10499/6612/9063/7155/25942/8021/6117/6294/6396/648/129401/11315/55746/8648/7421/8480/10891/7508/6015/4193/8554 128 Simian_virus_40 R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 125/2223 182/10654 1.496905958896793e-44 6.480154183353214e-43 2.897237339800245e-43 1912/23165/7020/23468/7150/5905/5893/6670/5903/7068/55706/7175/1487/55143/5241/83746/3622/9631/5468/7021/1029/7486/1788/9112/8535/51564/1786/6045/9212/51588/7518/3619/4869/3090/80012/7153/10274/348995/79023/6613/57122/23636/10735/8517/332/10762/5465/5885/23511/10210/28996/53371/1655/5970/4792/3190/6996/9612/8856/1911/6790/641/23137/6672/5111/2099/23279/4927/9688/79902/9656/9883/7341/1387/84733/10401/1616/23225/2908/2033/23512/165918/8243/9126/57332/7022/142/7428/3066/3065/7157/1107/1069/8086/7329/5987/5371/8924/672/115426/7158/10155/367/9972/10499/6612/9063/7155/25942/8021/6117/6294/6396/648/129401/11315/55746/8648/7421/8480/10891/7508/6015/4193/8554 125 Simian_virus_40 R-HSA-69618 Mitotic Spindle Checkpoint 92/2223 112/10654 4.0609770078124745e-44 1.7030722326513564e-42 7.61433188964839e-43 220134/5905/55839/11130/79682/5903/10403/11065/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/7321/991/401541/79019/5526/348235/80152/9212/1063/8379/3619/79172/147841/348995/23421/55920/79023/57122/79980/64105/6232/332/1780/8881/23122/5528/5048/1781/5501/57405/8655/4085/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/22919/1060/91687/79003/5529/51143/83540/11004/5527/701/7514/9184/5518/54820/5347/57551/84643/29882/6396/23332/25909/64946/9793/10726/81930/55746/140735/996/5515/1778/5516 92 Simian_virus_40 R-HSA-68877 Mitotic Prometaphase 132/2223 200/10654 5.514762283684918e-44 2.2426699953651996e-42 1.002684051579076e-42 10844/115106/220134/5905/55839/11130/22995/79682/5903/10403/54908/6249/55143/64151/22981/55055/25936/5525/9735/7531/80776/1459/1783/1058/991/401541/203068/79019/5526/51807/7532/1454/348235/80152/9212/1063/8379/3619/79172/10274/1460/147841/23244/7277/348995/23421/55920/79023/9133/57122/79980/64105/10735/6232/332/23047/1780/10051/23122/5885/5528/5048/1781/891/5501/57405/8655/4085/1457/983/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/7846/7283/3320/22919/80097/1060/91687/79003/8243/9126/23397/5529/51143/9918/10540/10733/1069/83540/4751/11004/5527/701/7514/9184/54930/5518/10383/55835/54820/5347/57551/113130/84790/84643/6396/9662/23332/1453/25909/64946/9793/10726/81930/55746/8481/140735/10592/7280/5515/1778/5516 132 Simian_virus_40 R-HSA-69615 G1/S DNA Damage Checkpoints 66/2223 68/10654 8.119722101420685e-43 3.204902076501929e-41 1.432892135544827e-41 5718/1017/5689/9134/5684/5720/5682/57060/1029/25946/5700/122706/5707/5690/5717/1027/9491/23198/898/11200/143471/5706/472/5705/10197/7316/10213/5709/993/5695/890/1026/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/7157/8900/5719/5704/6233/5716/7311/5694/51230/5693/5721/5696/5691/7314/4193 66 Simian_virus_40 R-HSA-69002 DNA Replication Pre-Initiation 76/2223 85/10654 3.7178244319292825e-42 1.4255201107568849e-40 6.373413311878771e-41 5718/1017/4172/6118/5689/5684/5720/8318/5682/5700/122706/5707/5690/5717/9491/23198/54107/4173/143471/5706/5705/10197/5557/7316/10213/5709/5422/1869/4174/5695/84515/5714/5426/4171/1871/9861/51053/5715/4998/6119/5711/5701/5688/5687/5427/5685/5683/5698/5708/5692/5686/5713/990/5699/4175/5710/81620/5702/5719/1870/5704/6233/55388/5716/7311/23649/6117/5694/5558/5693/5721/5696/5691/4176/7314/56655 76 Simian_virus_40 R-HSA-69563 p53-Dependent G1 DNA Damage Response 64/2223 66/10654 1.8399360126943236e-41 6.673497646042655e-40 2.98368002058539e-40 5718/1017/5689/9134/5684/5720/5682/57060/1029/25946/5700/122706/5707/5690/5717/1027/9491/23198/898/11200/143471/5706/472/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/8900/5719/5704/6233/5716/7311/5694/51230/5693/5721/5696/5691/7314/4193 64 Simian_virus_40 R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 64/2223 66/10654 1.8399360126943236e-41 6.673497646042655e-40 2.98368002058539e-40 5718/1017/5689/9134/5684/5720/5682/57060/1029/25946/5700/122706/5707/5690/5717/1027/9491/23198/898/11200/143471/5706/472/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/8900/5719/5704/6233/5716/7311/5694/51230/5693/5721/5696/5691/7314/4193 64 Simian_virus_40 R-HSA-453274 Mitotic G2-G2/M phases 128/2223 198/10654 3.3418225936181206e-41 1.180191031746189e-39 5.276561989923348e-40 10844/115106/5718/1017/5689/8945/22995/5684/994/5720/4605/902/2305/5682/22981/7531/51512/4659/5700/122706/5707/203068/51807/7532/1454/22974/5690/3161/1063/5717/9491/23198/6500/7277/143471/5706/9133/5705/10197/286826/5048/1781/7316/10213/5709/9978/1869/891/993/5695/890/8655/4331/983/1026/6790/5714/1871/9861/5715/5519/5711/5928/5701/5688/5687/91750/23291/7846/5685/7283/5683/5698/5708/3320/5692/22919/5686/5713/80097/2033/995/5699/5710/5702/10540/5520/7157/10733/8900/1069/5719/4751/5704/6233/3326/5716/28227/55957/7514/7311/54930/23194/5518/10383/55835/54820/5347/84790/9662/5694/23332/1453/7465/9793/1022/8481/5693/5721/5696/7280/132660/5691/5500/7314/5515/1778/5516 128 Simian_virus_40 R-HSA-5685942 HDR through Homologous Recombination (HRR) 64/2223 67/10654 3.2842773467055083e-40 1.1301282562253312e-38 5.052734379546935e-39 51750/6118/80010/83990/7516/5888/5892/9156/5883/1763/7486/10111/57804/675/5982/54107/545/472/80198/580/11073/7316/116028/197342/5425/641/5111/5426/10635/7517/6119/84464/3364/10524/4683/5427/144715/5889/5429/5985/84126/1111/5984/23514/79728/6233/51426/146956/672/5932/7311/7156/5890/5983/6117/5981/10714/5884/5810/5424/348654/83695/7314/56655 64 Simian_virus_40 R-HSA-69275 G2/M Transition 126/2223 196/10654 3.4742814002284403e-40 1.1656214097766416e-38 5.211422100342661e-39 10844/115106/5718/1017/5689/8945/22995/5684/994/5720/4605/902/2305/5682/22981/7531/51512/4659/5700/122706/5707/203068/51807/7532/1454/22974/5690/3161/1063/5717/9491/23198/6500/7277/143471/5706/9133/5705/10197/286826/5048/1781/7316/10213/5709/9978/891/993/5695/890/8655/4331/983/1026/6790/5714/9861/5715/5519/5711/5928/5701/5688/5687/91750/23291/7846/5685/7283/5683/5698/5708/3320/5692/22919/5686/5713/80097/2033/995/5699/5710/5702/10540/5520/7157/10733/8900/1069/5719/4751/5704/6233/3326/5716/28227/55957/7514/7311/54930/23194/5518/10383/55835/54820/5347/84790/9662/5694/23332/1453/7465/9793/1022/8481/5693/5721/5696/7280/132660/5691/5500/7314/5515/1778/5516 126 Simian_virus_40 R-HSA-109581 Apoptosis 118/2223 178/10654 1.092284296639776e-39 3.575232990464828e-38 1.5984648243508918e-38 23368/4000/5718/5689/2934/27113/3837/596/5684/5720/1612/5682/1499/10018/7531/5747/1029/7027/842/5700/122706/5707/7532/207/10971/5690/5594/5717/9491/23198/63967/355/7533/2810/118/143471/5706/5705/841/10197/7099/7534/9500/7316/10213/5709/1869/5695/8655/6774/54205/5339/4836/5366/5714/8797/3146/9861/5715/5711/5701/28988/5688/329/5687/999/598/56616/836/5685/5683/5698/5708/10000/5692/5686/5713/8837/5534/5699/5710/3002/5702/7157/90427/8626/5719/208/5704/6233/5580/5716/1613/7311/7161/839/7029/840/331/581/5599/7159/7431/5694/57099/26060/637/317/8795/5693/5721/140735/5696/5691/7529/7314/578/5595 118 Simian_virus_40 R-HSA-168254 Influenza Infection 108/2223 155/10654 1.5931080375605175e-39 5.090359491443368e-38 2.2758686250864536e-38 6158/23165/3303/6138/6144/2963/3837/3838/6203/5434/5440/5903/9349/4736/6206/6194/6191/55706/7175/6128/51121/6132/9631/6147/6129/6217/5430/6222/5436/6152/6136/6125/6154/51065/348995/6141/9636/6202/79023/57122/5441/23636/6232/5438/10762/5431/6160/23511/5435/6155/6175/293/6218/53371/5433/6209/23279/4927/6231/9688/6229/79902/6130/2962/6142/3840/6204/9883/5437/23225/3320/140801/6156/6143/6181/5439/6124/5901/6207/8086/6233/7514/7311/6223/9972/1213/5610/1211/3921/6188/6189/8021/7040/6396/6135/6201/129401/3304/9045/6187/5432/55746/6168/6208/6137/8480/6122/6230 108 Simian_virus_40 R-HSA-5357801 Programmed Cell Death 119/2223 181/10654 1.8226487234800088e-39 5.68835950444226e-38 2.5432307769488493e-38 23368/4000/5718/5689/2934/27113/3837/596/5684/5720/1612/5682/1499/10018/7531/5747/1029/7027/842/5700/122706/5707/7532/207/10971/5690/5594/5717/9491/23198/63967/355/330/7533/2810/118/143471/5706/5705/841/10197/7099/7534/9500/7316/10213/5709/1869/5695/8655/6774/54205/5339/4836/5366/5714/8797/3146/9861/5715/5711/5701/28988/5688/329/5687/999/598/56616/836/5685/5683/5698/5708/10000/5692/5686/5713/8837/5534/5699/5710/3002/5702/7157/90427/8626/5719/208/5704/6233/5580/5716/1613/7311/7161/839/7029/840/331/581/5599/7159/7431/5694/57099/26060/637/317/8795/5693/5721/140735/5696/5691/7529/7314/578/5595 119 Simian_virus_40 R-HSA-8878166 Transcriptional regulation by RUNX2 92/2223 121/10654 6.155658564555805e-39 1.8774758621895207e-37 8.394079860757917e-38 57154/5718/8493/5689/7291/25/1019/5684/8841/5720/5682/5700/122706/5707/23462/10273/207/5690/5594/3280/5717/9491/23198/6500/4086/5925/10013/143471/5706/5705/1277/10197/632/7316/10213/5709/9978/891/865/5695/4094/983/1026/10413/5714/6772/6714/2099/9861/4089/5715/5711/2932/5701/5688/5687/6502/4322/2908/5685/5683/5698/5708/10000/5692/5686/5713/595/55294/5699/5710/5702/5719/208/5704/6233/25925/5716/7311/25937/367/860/581/5694/5693/5721/5696/5691/117581/10891/7314/5595 92 Simian_virus_40 R-HSA-168255 Influenza Life Cycle 102/2223 144/10654 2.1323873500736836e-38 6.359252941775297e-37 2.843183133431578e-37 6158/23165/3303/6138/6144/2963/3837/6203/5434/5440/5903/9349/4736/6206/6194/6191/55706/7175/6128/51121/6132/9631/6147/6129/6217/5430/6222/5436/6152/6136/6125/6154/51065/348995/6141/6202/79023/57122/5441/23636/6232/5438/10762/5431/6160/23511/5435/6155/6175/6218/53371/5433/6209/23279/4927/6231/9688/6229/79902/6130/2962/6142/6204/9883/5437/23225/3320/140801/6156/6143/6181/5439/6124/5901/6207/8086/6233/7514/7311/6223/9972/1213/1211/3921/6188/6189/8021/6396/6135/6201/129401/3304/9045/6187/5432/55746/6168/6208/6137/8480/6122/6230 102 Simian_virus_40 R-HSA-5663220 RHO GTPases Activate Formins 100/2223 140/10654 3.5218687498948343e-38 1.0274669265997538e-36 4.5937418476889144e-37 220134/5905/55839/11130/79682/5903/10403/54908/6249/55143/55055/25936/5525/9735/80776/1783/1058/991/1856/401541/79019/5526/51807/348235/80152/9212/1063/8379/3619/79172/147841/7277/348995/23421/55920/79023/57122/79980/64105/6232/332/1780/23122/5528/3688/5048/1781/5501/57405/8655/4085/81624/6714/23279/55166/79902/3796/54821/5519/9183/81565/2491/1062/699/7846/51466/22919/1060/91687/79003/5529/51143/998/83540/11004/5527/701/7514/9184/5518/10383/54820/5347/57551/60/84790/84643/6396/23332/25909/64946/9793/10726/81930/55746/140735/7280/5515/1778/5516 100 Simian_virus_40 R-HSA-162587 HIV Life Cycle 105/2223 152/10654 6.54499662144735e-38 1.8688054182941156e-36 8.355314835890235e-37 6884/23165/6875/5905/2963/2237/6917/5434/5440/5903/7852/902/55706/7175/9631/3159/5430/6874/5436/7518/7520/6878/404672/6749/348995/10015/79023/57122/5441/23636/5438/3978/3981/10762/5431/7469/23511/5435/7316/6872/53371/4331/5433/4836/9397/23279/4927/9688/8148/2966/79902/6879/9150/2962/9883/54457/5437/8812/83860/23225/2965/128866/905/2068/5439/2071/5901/8086/5478/6873/6827/6233/2968/7514/1025/7311/9972/6881/2967/51616/6880/6908/8021/7251/11198/6396/129401/904/6883/7936/6829/1104/51497/2547/6882/138474/1022/5432/55746/1234/8178/8480/6877/7314/25920 105 Simian_virus_40 R-HSA-8878171 Transcriptional regulation by RUNX1 139/2223 239/10654 3.94869323041802e-37 1.1039888156710381e-35 4.9358665380225254e-36 55904/1912/5718/6595/9070/5689/27161/25/894/5684/3562/4773/8861/5720/902/1437/11091/5579/6597/5682/6929/1459/5700/122706/5707/8535/6045/9021/5690/2625/57690/5717/5929/9491/23198/27327/80012/1460/4005/143471/5706/6598/5705/10197/6599/192670/86/7316/10213/5709/865/5695/28996/5079/10398/1457/4331/1911/6603/10413/5714/23309/51412/6714/2099/9861/5715/8850/5711/5701/5688/1387/84733/5687/3558/5685/6604/5683/8289/5698/5708/5692/5686/5713/2033/1021/6605/6602/57332/595/50943/5699/6886/4602/8312/5710/3458/5702/192669/3065/83737/896/5719/5371/23112/57492/5704/6233/5716/7311/6688/7161/860/58508/25942/9739/4343/648/8784/3276/5694/3977/6601/3559/23466/26523/7057/1022/1493/5693/5721/23429/4297/5696/5691/1997/7314/6015/1514 139 Simian_virus_40 R-HSA-1169091 Activation of NF-kappaB in B cells 62/2223 67/10654 1.0161698205275738e-36 2.783061018669396e-35 1.244289576156213e-35 1147/5718/5689/8945/5684/5720/4790/6885/5579/5966/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/8517/7316/10213/5709/5695/5970/4792/4793/8915/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/3551/5693/5721/5696/5691/7314 62 Simian_virus_40 R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 71/2223 83/10654 1.2870822963539553e-36 3.454528883414016e-35 1.5444987556247461e-35 1147/5718/5689/8945/5684/4893/4773/5720/4790/6885/5579/5966/5682/4772/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/8517/5530/7316/10213/5709/5695/5970/4792/4793/8915/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5534/5699/5710/5702/2280/5478/5719/5704/6233/5716/7311/3845/5694/3265/3551/5693/5721/5696/5691/7314 71 Simian_virus_40 R-HSA-68949 Orc1 removal from chromatin 64/2223 71/10654 3.720270185807223e-36 9.789416841869203e-35 4.376788453890851e-35 5718/1017/4172/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/4173/143471/5706/5705/10197/7316/10213/5709/9978/4174/5695/890/84515/5714/4171/9861/5715/4998/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/990/5699/4175/5710/81620/5702/8900/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/4176/7314 64 Simian_virus_40 R-HSA-5663202 Diseases of signal transduction 186/2223 377/10654 5.467343202478595e-36 1.4109951111012067e-34 6.30847292593684e-35 4000/1147/5718/2308/27123/5947/5689/2963/8805/5434/5440/7276/5684/4893/8841/5290/5720/5335/79885/1487/2309/5682/1499/2648/10018/5525/9734/892/842/5700/3815/122706/5707/5430/5526/23462/207/51564/5436/1452/5690/5594/3280/4303/613/5717/1027/9491/7249/23198/6500/5908/930/941/10533/10013/143471/5706/2064/5705/5441/10197/5438/5431/6776/5528/2100/5435/84447/7316/10213/5709/9978/1950/9611/5695/8546/6774/4233/9612/1026/5433/1024/5714/6772/6714/2099/4609/7415/9861/4089/10014/5715/2962/22938/5037/5519/8850/8503/5711/2932/5701/5688/1387/5437/5159/5687/3717/4088/2247/5685/3164/5683/5698/5708/10000/3320/5692/5686/5713/2335/2033/54894/55294/5728/5699/8312/5529/5710/5439/2264/5702/3066/3065/2280/2066/5894/4087/942/5719/208/9794/5704/6233/5527/2885/2475/5716/2246/1385/7311/8826/5154/5518/5155/2243/2252/6469/1956/60/7040/3845/2549/6777/5694/3265/3516/369/4763/4851/5432/5693/5663/5721/5696/5691/5245/7529/5156/940/7314/1523/5595/4193/5515/5516 186 Simian_virus_40 R-HSA-168273 Influenza Viral RNA Transcription and Replication 95/2223 134/10654 7.01871540644975e-36 1.7771917123501064e-34 7.945715554471415e-35 6158/23165/6138/6144/2963/6203/5434/5440/5903/9349/4736/6206/6194/6191/55706/7175/6128/51121/6132/9631/6147/6129/6217/5430/6222/5436/6152/6136/6125/6154/51065/348995/6141/6202/79023/57122/5441/23636/6232/5438/10762/5431/6160/23511/5435/6155/6175/6218/53371/5433/6209/23279/4927/6231/9688/6229/79902/6130/2962/6142/6204/9883/5437/23225/3320/140801/6156/6143/6181/5439/6124/6207/8086/6233/7311/6223/9972/3921/6188/6189/8021/6396/6135/6201/129401/9045/6187/5432/55746/6168/6208/6137/8480/6122/6230 95 Simian_virus_40 R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 72/2223 86/10654 7.841295376272856e-36 1.9132760718105768e-34 8.55414041047948e-35 5718/1017/5689/8945/5684/5720/11065/5682/5700/122706/7321/5707/991/5690/9212/5717/9491/23198/6500/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/6790/5714/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/8556/5719/4751/9232/5704/6233/5716/701/51343/7311/9184/5347/29882/5694/5693/5721/5696/5691/7314/996 72 Simian_virus_40 R-HSA-453276 Regulation of mitotic cell cycle 72/2223 86/10654 7.841295376272856e-36 1.9132760718105768e-34 8.55414041047948e-35 5718/1017/5689/8945/5684/5720/11065/5682/5700/122706/7321/5707/991/5690/9212/5717/9491/23198/6500/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/6790/5714/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/8556/5719/4751/9232/5704/6233/5716/701/51343/7311/9184/5347/29882/5694/5693/5721/5696/5691/7314/996 72 Simian_virus_40 R-HSA-68867 Assembly of the pre-replicative complex 62/2223 68/10654 9.203923775360483e-36 2.2056545904524588e-34 9.861346902171947e-35 5718/4172/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/4173/143471/5706/5705/10197/7316/10213/5709/1869/4174/5695/84515/5714/4171/1871/9861/51053/5715/4998/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/990/5699/4175/5710/81620/5702/5719/1870/5704/6233/5716/7311/5694/5693/5721/5696/5691/4176/7314 62 Simian_virus_40 R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 57/2223 60/10654 1.5854189452128898e-35 3.73268811311526e-34 1.6688620475925155e-34 5718/1017/5689/9134/1019/5684/5720/5682/5700/5707/5690/5717/1027/9491/6500/898/5706/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/595/5699/5710/5702/8900/5719/5704/6233/5716/7311/5694/1163/5693/5721/5696/5691/7314 57 Simian_virus_40 R-HSA-69541 Stabilization of p53 55/2223 57/10654 2.212243165216058e-35 5.1186729788275e-34 2.288527412292474e-34 5718/5689/5684/5720/5682/1029/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/472/5705/10197/7316/10213/5709/5695/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/51230/5693/5721/5696/5691/7314/4193 55 Simian_virus_40 R-HSA-9020702 Interleukin-1 signaling 80/2223 103/10654 3.5852376420957355e-35 8.154896467275386e-34 3.646004381792273e-34 3557/1147/5718/5689/8945/5684/351/5720/4790/6885/5682/4215/5700/122706/5707/5690/3553/8878/5717/9491/23198/6500/143471/5706/5705/10197/8517/4615/7316/10213/5709/9978/5695/5970/4792/4793/5714/3146/9861/5715/64127/5711/3552/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/3656/5699/57162/5710/10454/6288/5702/5719/3654/7189/6285/5704/6233/5716/7311/7334/5694/3551/7850/57161/5693/5721/5696/5691/3554/7314 80 Simian_virus_40 R-HSA-5693538 Homology Directed Repair 96/2223 138/10654 3.812705361250998e-35 8.527750991331399e-34 3.8127053612509982e-34 51750/1017/6118/80010/54962/25/2237/5893/83990/7516/5888/5892/9156/5883/1763/7486/10111/57804/51588/51720/675/7515/5982/63967/54107/5531/51548/545/472/6613/80198/7336/580/11073/2072/29086/7316/116028/890/197342/5425/641/5111/5426/10635/7517/9656/6119/84464/3364/7341/10524/4683/5427/144715/5889/5429/5985/165918/84126/142/8914/1111/8900/5984/23514/7329/79728/8924/6233/2067/51426/146956/672/5932/7158/7311/6047/9025/79184/3980/7156/5890/5983/6117/7334/5981/10038/10714/5884/5810/5424/348654/83695/7314/56655 96 Simian_virus_40 R-HSA-162909 Host Interactions of HIV factors 92/2223 129/10654 4.077508975054785e-35 8.970519745120528e-34 4.010664565627658e-34 5718/23165/5689/5905/8945/3837/5684/5903/5720/55706/7175/162/5682/9631/3159/5700/122706/5707/5690/5717/4869/9491/23198/6500/348995/143471/79023/5706/57122/5705/23636/10197/10762/23511/7316/10213/5709/9978/293/5695/53371/292/567/5714/23279/4927/9688/9861/79902/5715/5711/9883/5701/5688/5687/23225/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5901/8086/5478/5719/5704/6233/5716/7514/1025/9844/7311/9972/8021/6396/129401/904/5694/1104/55746/5693/5721/5696/5691/8480/940/7314 92 Simian_virus_40 R-HSA-162599 Late Phase of HIV Life Cycle 96/2223 139/10654 9.860847109965407e-35 2.134396261544125e-33 9.542755267708458e-34 6884/23165/6875/5905/2963/6917/5434/5440/5903/902/55706/7175/9631/5430/6874/5436/6878/404672/6749/348995/10015/79023/57122/5441/23636/5438/10762/5431/7469/23511/5435/7316/6872/53371/4331/5433/4836/9397/23279/4927/9688/8148/2966/79902/6879/9150/2962/9883/54457/5437/8812/83860/23225/2965/128866/905/2068/5439/2071/5901/8086/5478/6873/6827/6233/2968/7514/1025/7311/9972/6881/2967/51616/6880/6908/8021/7251/11198/6396/129401/904/6883/7936/6829/1104/51497/6882/138474/1022/5432/55746/8178/8480/6877/7314/25920 96 Simian_virus_40 R-HSA-8878159 Transcriptional regulation by RUNX3 76/2223 96/10654 1.6660245014224844e-34 3.5488966363634506e-33 1.586690001354747e-33 57154/5718/5689/8463/5684/5720/2309/5682/1499/2648/10018/1029/864/5700/5707/5690/3280/5717/9491/5706/5705/6097/10197/6696/7316/10213/5709/865/5695/1026/10413/5714/6714/4609/9861/4089/5715/22938/8850/5711/5701/5688/1387/5687/4088/5685/5683/5698/5708/5692/5686/5713/2033/595/5699/5710/5702/7157/5719/9794/5704/6233/5716/7311/25937/7040/3845/5694/3516/4851/5693/5721/5696/5691/7314/4193 76 Simian_virus_40 R-HSA-8941858 Regulation of RUNX3 expression and activity 53/2223 55/10654 4.91413927053276e-34 1.0131353119037969e-32 4.5296660740855306e-33 57154/5718/5689/5684/5720/5682/1029/864/5700/5707/5690/5717/9491/5706/5705/10197/7316/10213/5709/865/5695/5714/6714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/2033/5699/5710/5702/5719/5704/6233/5716/7311/7040/5694/5693/5721/5696/5691/7314/4193 53 Simian_virus_40 R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 51/2223 52/10654 5.133621550630268e-34 1.0131353119037969e-32 4.5296660740855306e-33 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Simian_virus_40 R-HSA-69610 p53-Independent DNA Damage Response 51/2223 52/10654 5.133621550630268e-34 1.0131353119037969e-32 4.5296660740855306e-33 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Simian_virus_40 R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 51/2223 52/10654 5.133621550630268e-34 1.0131353119037969e-32 4.5296660740855306e-33 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Simian_virus_40 R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 51/2223 52/10654 5.133621550630268e-34 1.0131353119037969e-32 4.5296660740855306e-33 5718/5689/1019/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/595/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Simian_virus_40 R-HSA-3371556 Cellular response to heat stress 72/2223 89/10654 6.689383075631367e-34 1.2824502982138992e-32 5.733756921969743e-33 23165/3303/6118/6782/5903/573/55706/7175/9631/7531/1915/116835/5594/3308/10049/348995/1410/10013/545/79023/472/57122/23636/3337/3313/10762/23511/3305/53371/9532/23279/4927/9688/7415/79902/6119/26353/9883/2932/1387/57805/259217/23225/3310/3309/3320/2033/7266/6767/9531/8086/22824/3326/2475/3306/9972/23411/8021/9529/6117/6396/129401/3304/3312/3297/57521/55746/2288/8480/10728/51182/5595 72 Simian_virus_40 R-HSA-5687128 MAPK6/MAPK4 signaling 72/2223 89/10654 6.689383075631367e-34 1.2824502982138992e-32 5.733756921969743e-33 5718/2308/5689/27161/3725/5684/5720/2309/5682/5700/10642/122706/5707/5690/57690/5717/9491/3315/23198/27327/143471/5706/5705/10197/3337/192670/8550/7316/10213/5709/5695/983/5597/5714/4609/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/8555/5702/192669/998/8556/896/5719/23112/5704/6233/5716/7514/7311/4343/5694/26523/8202/5693/5721/5696/5691/7314 72 Simian_virus_40 R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 81/2223 108/10654 1.1660491489844337e-33 2.2039971238550842e-32 9.853936470290989e-33 3605/7124/2308/1052/7291/596/2208/3592/3566/2309/3561/7184/3593/207/3911/5292/3684/9021/7422/3553/2625/4582/5743/3091/4318/6367/4312/3383/301/6097/6657/6778/3576/332/3662/3597/3688/4313/3565/3976/6774/4314/1026/7133/3606/6772/8651/4609/149233/4988/3552/79923/3717/598/2247/3320/2335/595/6288/7157/112744/3716/2353/604/6347/7076/7040/6935/3687/51561/3570/7431/6356/3312/7297/3569/3162/4170/3586/4692/3596 81 Simian_virus_40 R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 52/2223 54/10654 2.3125265333334356e-33 4.2512474078540694e-32 1.9007067397261116e-32 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/6790/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/23194/5694/5693/5721/5696/5691/7314 52 Simian_virus_40 R-HSA-9604323 Negative regulation of NOTCH4 signaling 52/2223 54/10654 2.3125265333334356e-33 4.2512474078540694e-32 1.9007067397261116e-32 5718/5689/5684/5720/5682/5700/5707/207/5690/5717/9491/6500/5706/5705/10197/10460/7534/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/4855/55294/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 52 Simian_virus_40 R-HSA-69052 Switching of origins to a post-replicative state 72/2223 90/10654 2.6736388429680473e-33 4.848680171977189e-32 2.167815278082201e-32 5718/1017/4172/5689/9134/5684/5720/11065/5682/5700/122706/7321/5707/5690/5717/9491/23198/6500/898/4173/143471/5706/5705/10197/8881/7316/10213/5709/9978/4174/5695/890/84515/5714/4171/9861/5715/4998/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/990/5699/4175/5710/81620/5702/8900/5719/5704/6233/5716/51343/7311/29882/5694/5693/5721/5696/5691/4176/7314/996 72 Simian_virus_40 R-HSA-5696398 Nucleotide Excision Repair 82/2223 111/10654 3.0234642011107374e-33 5.40998527718748e-32 2.41877136088859e-32 9318/6118/6917/5434/5440/902/2074/5430/57804/5436/7515/5982/404672/54107/6613/5441/7507/7336/86/5438/3978/5431/2072/8450/5435/7316/9978/4331/5425/5433/5111/5426/1643/2966/6119/7341/5437/10401/5427/1161/1642/2965/5985/2033/142/2068/5439/10987/2071/5984/1069/7329/6233/2067/51426/2873/2968/7311/2967/6612/3980/60/5887/5983/6117/7334/5981/10038/10714/7874/5424/1022/5432/8178/5886/7508/7314/51138/8451/8554/7528/56655 82 Simian_virus_40 R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 91/2223 132/10654 7.021450954594093e-33 1.2398404185612202e-31 5.543250753626915e-32 51750/1017/6118/80010/54962/25/5893/83990/7516/5888/5892/9156/5883/1763/7486/10111/57804/51588/51720/675/5982/63967/54107/5531/51548/545/472/6613/80198/7336/580/11073/2072/29086/7316/116028/890/197342/5425/641/5111/5426/10635/7517/9656/6119/84464/3364/7341/10524/4683/5427/144715/5889/5429/5985/165918/84126/8914/1111/8900/5984/23514/7329/79728/8924/6233/2067/51426/146956/672/5932/7158/7311/6047/9025/79184/7156/5890/5983/6117/7334/5981/10714/5884/5810/5424/348654/83695/7314/56655 91 Simian_virus_40 R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 53/2223 56/10654 7.330107852671471e-33 1.2775330828941707e-31 5.711772352731017e-32 5718/3303/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/3315/23198/26986/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/3304/3312/5693/5721/5696/5691/7314 53 Simian_virus_40 R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 58/2223 65/10654 2.6887192406167803e-32 4.625975924240665e-31 2.0682455697052156e-31 2176/3725/2963/6917/5434/5440/4436/8621/902/5892/5430/5436/404672/6749/4292/545/472/5441/5438/5431/7469/5435/4331/5433/1643/2966/5395/9150/2962/9656/5437/8812/2177/2965/51755/905/2068/5439/1111/2071/7157/55215/6827/2968/672/1025/2353/2967/1386/11198/904/7936/6829/51497/1022/5432/8178/25920 58 Simian_virus_40 R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 64/2223 76/10654 2.829634520723086e-32 4.80679686938023e-31 2.149089509409939e-31 5718/5689/5684/5720/11065/5682/5700/122706/7321/5707/991/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/5719/4751/9232/5704/6233/5716/701/7311/9184/5347/29882/5694/5693/5721/5696/5691/7314/996 64 Simian_virus_40 R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 52/2223 55/10654 3.3878478375522926e-32 5.68311474749397e-31 2.54088587816422e-31 5718/5689/8945/5684/5720/5682/5700/122706/5707/991/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/51343/7311/5694/5693/5721/5696/5691/7314 52 Simian_virus_40 R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 66/2223 80/10654 3.6537032333360134e-32 6.053419431033247e-31 2.7064468395081583e-31 5718/1017/5689/8945/5684/5720/11065/5682/5700/122706/7321/5707/991/5690/5717/9491/23198/6500/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/5719/5704/6233/5716/701/51343/7311/9184/5347/29882/5694/5693/5721/5696/5691/7314/996 66 Simian_virus_40 R-HSA-180534 Vpu mediated degradation of CD4 50/2223 52/10654 5.104758481729029e-32 8.253717930699224e-31 3.690186854261949e-31 5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Simian_virus_40 R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/2223 52/10654 5.104758481729029e-32 8.253717930699224e-31 3.690186854261949e-31 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/472/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Simian_virus_40 R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 48/2223 49/10654 5.615409217299592e-32 8.971284725733396e-31 4.0110065837854235e-31 1017/9134/1820/57060/7027/25946/7832/4849/1027/4869/898/4850/2810/9337/5934/1869/891/890/10769/983/1026/6790/5933/5111/25904/246175/1647/4848/23019/28984/2033/995/1874/7157/8900/10498/55571/7029/55835/5325/581/57472/3276/144455/85456/79733/29883/1263 48 Simian_virus_40 R-HSA-8948751 Regulation of PTEN stability and activity 60/2223 69/10654 5.834767843108499e-32 9.212068759354831e-31 4.118659653958941e-31 5718/5689/5684/5720/5682/1459/5700/122706/5707/10273/207/5690/5717/9491/23198/1460/143471/5706/5705/10197/7316/10213/5709/5695/1457/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/10000/5692/5686/5713/5728/5699/2444/5710/5702/5719/5987/208/5704/6233/5716/7311/331/5694/5693/5721/5696/23608/5691/7314 60 Simian_virus_40 R-HSA-8939902 Regulation of RUNX2 expression and activity 62/2223 73/10654 9.754688980734746e-32 1.5221851874588404e-30 6.805596963303312e-31 57154/5718/5689/7291/5684/5720/5682/5700/122706/5707/10273/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/865/5695/5714/6772/2099/9861/5715/5711/2932/5701/5688/5687/6502/2908/5685/5683/5698/5708/5692/5686/5713/55294/5699/5710/5702/5719/5704/6233/5716/7311/860/5694/5693/5721/5696/5691/10891/7314 62 Simian_virus_40 R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 63/2223 75/10654 1.1679690418285986e-31 1.8016258093494016e-30 8.05495890916275e-31 5718/5689/5684/5720/11065/5682/5700/122706/7321/5707/991/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/5719/4751/9232/5704/6233/5716/701/7311/9184/29882/5694/5693/5721/5696/5691/7314/996 63 Simian_virus_40 R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 64/2223 77/10654 1.3394560100256226e-31 2.0197190623082986e-30 9.03004051702667e-31 1912/23165/5893/5903/55706/7175/9631/1029/7486/8535/51564/6045/51588/7518/80012/10274/348995/79023/6613/57122/23636/10735/10762/5885/23511/53371/6996/1911/641/23137/6672/23279/4927/9688/79902/9656/9883/7341/84733/23225/165918/8243/9126/57332/142/1069/8086/7329/5371/8924/672/9972/6612/9063/8021/6117/6396/648/129401/55746/8480/7508/6015/8554 64 Simian_virus_40 R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 64/2223 77/10654 1.3394560100256226e-31 2.0197190623082986e-30 9.03004051702667e-31 5718/5689/5684/5720/5682/51512/5700/122706/5707/51807/5690/5717/9491/23198/7277/143471/5706/9133/5705/10197/7316/10213/5709/891/5695/983/1026/5714/9861/5715/5711/5701/5688/5687/7846/5685/5683/5698/5708/3320/5692/22919/5686/5713/5699/5710/5702/7157/5719/5704/6233/3326/5716/7311/10383/5347/84790/5694/5693/5721/5696/7280/5691/7314 64 Simian_virus_40 R-HSA-9010553 Regulation of expression of SLITs and ROBOs 105/2223 171/10654 4.27694800628533e-31 6.37740469381657e-30 2.851298670856887e-30 6158/5718/5689/6138/6144/6203/5684/9349/4736/8861/5720/6206/6194/6191/6128/5682/51121/6132/6147/6129/6217/5700/122706/5707/6222/6152/5690/6136/6125/5717/9491/23198/6154/51065/6141/26986/143471/6202/5706/5705/10197/6232/6160/7316/6155/10213/5709/6175/9978/6218/5695/6209/5714/6231/6229/9861/6130/5715/6142/5711/6204/5701/5688/5687/5685/1605/5683/5698/5708/5692/5686/5713/140801/6156/5699/6143/5710/6181/6124/5702/6207/5719/5704/6233/5716/7311/6223/3921/6188/6189/6135/6201/5694/9045/6187/6168/5693/6208/5721/6137/5696/5691/6122/7314/6230 105 Simian_virus_40 R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 69/2223 88/10654 5.956391435466488e-31 8.78404099603959e-30 3.927291056351531e-30 5718/3303/5689/5684/5720/5682/5700/122706/5707/207/5690/5578/5717/9491/3315/23198/26986/143471/5706/5705/10197/7534/7316/10213/5709/5695/5714/9861/5715/5711/1432/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/51013/5702/5719/5704/6233/5580/5716/7514/7311/11340/8021/5600/5694/3304/3312/8570/6418/23016/5693/54512/5721/5696/5691/7529/7314/1994 69 Simian_virus_40 R-HSA-195253 Degradation of beta-catenin by the destruction complex 66/2223 82/10654 6.458842884324038e-31 9.42148603343789e-30 4.212288837602633e-30 5718/5689/8945/5684/5720/1487/5682/1499/5525/5700/122706/5707/5526/1452/5690/5717/9491/23198/6500/143471/5706/5705/10197/5528/7316/10213/5709/9978/5695/5714/9861/5715/5519/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/8312/5529/5710/5702/3065/5719/5704/6233/5527/5716/7311/5518/5694/5693/5721/5696/5691/7314/5515/5516 66 Simian_virus_40 R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 48/2223 50/10654 1.121839616717572e-30 1.618826629715034e-29 7.23767494656498e-30 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 48 Simian_virus_40 R-HSA-3371453 Regulation of HSF1-mediated heat shock response 59/2223 69/10654 1.369467207431326e-30 1.9329995996781822e-29 8.642323098412139e-30 23165/3303/6118/6782/5903/573/55706/7175/9631/7531/116835/5594/3308/10049/348995/545/79023/472/57122/23636/3337/3313/10762/23511/3305/53371/9532/23279/4927/9688/79902/6119/9883/2932/57805/259217/23225/3310/3309/7266/6767/9531/8086/22824/3306/9972/23411/8021/9529/6117/6396/129401/3304/3312/3297/55746/8480/51182/5595 59 Simian_virus_40 R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 54/2223 60/10654 1.3827716957459425e-30 1.9329995996781822e-29 8.642323098412139e-30 1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5970/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 54 Simian_virus_40 R-HSA-5610780 Degradation of GLI1 by the proteasome 54/2223 60/10654 1.3827716957459425e-30 1.9329995996781822e-29 8.642323098412139e-30 5718/5689/8945/5684/5720/2735/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/8650/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/83737/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 54 Simian_virus_40 R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 61/2223 73/10654 1.9728492610366688e-30 2.729447121970319e-29 1.2203191305381458e-29 5718/5689/5684/5720/11065/5682/5700/122706/7321/5707/991/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/890/4085/983/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/5719/4751/5704/6233/5716/701/7311/9184/29882/5694/5693/5721/5696/5691/7314/996 61 Simian_virus_40 R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 64/2223 79/10654 2.5102873870682664e-30 3.437556809638381e-29 1.5369106451438367e-29 9318/6118/6917/5434/5440/902/2074/5430/57804/5436/7515/5982/404672/54107/5441/7507/5438/3978/5431/2072/8450/5435/7316/9978/4331/5425/5433/5111/5426/2966/6119/5437/5427/1161/1642/2965/5985/2033/2068/5439/10987/2071/5984/6233/2067/51426/2873/2968/7311/2967/3980/5983/6117/5981/10714/7874/5424/1022/5432/8178/7314/51138/8451/56655 64 Simian_virus_40 R-HSA-4641258 Degradation of DVL 52/2223 57/10654 3.452614205765845e-30 4.6802103678159225e-29 2.0924934580399058e-29 5718/5689/5684/5720/5682/5700/122706/5707/1856/5690/5717/9491/23198/143471/5706/5705/10197/8452/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/23072/7311/5694/5693/5721/5696/5691/7314 52 Simian_virus_40 R-HSA-5676590 NIK-->noncanonical NF-kB signaling 53/2223 59/10654 6.0795284004980986e-30 8.077947637097474e-29 3.6116010299988704e-29 1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 53 Simian_virus_40 R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 53/2223 59/10654 6.0795284004980986e-30 8.077947637097474e-29 3.6116010299988704e-29 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/84515/5714/9861/51053/5715/4998/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/990/5699/5710/81620/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 53 Simian_virus_40 R-HSA-446652 Interleukin-1 family signaling 91/2223 140/10654 7.785334922866267e-30 1.024305830047699e-28 4.579608778156628e-29 3557/1147/5718/834/5689/8945/5684/351/5720/4790/6885/5682/90865/4215/5700/122706/5707/5690/3553/8878/5717/9491/23198/6500/143471/5706/5705/10197/8517/4615/7316/3565/10213/5709/9978/5695/6774/5970/4792/4793/5714/3606/3146/9861/5715/64127/5711/3552/5701/5688/5687/23291/4088/5685/5683/5698/5708/5692/5686/5713/3656/5699/57162/5771/5710/10454/6288/5702/5719/3654/7189/27177/6285/5704/6233/5716/7311/5599/5784/7334/5694/3551/7850/57161/5693/5721/5696/5691/3554/7314/3596 91 Simian_virus_40 R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 60/2223 72/10654 8.072181178694e-30 1.031701632553081e-28 4.612674959253714e-29 5718/5689/5684/5720/11065/5682/5700/122706/7321/5707/991/5690/9212/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/6790/5714/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/9232/5704/6233/5716/51343/7311/5347/29882/5694/5693/5721/5696/5691/7314/996 60 Simian_virus_40 R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 60/2223 72/10654 8.072181178694e-30 1.031701632553081e-28 4.612674959253714e-29 5718/5689/5684/5720/11065/5682/5700/122706/7321/5707/991/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/890/4085/983/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/8900/5719/5704/6233/5716/701/7311/9184/29882/5694/5693/5721/5696/5691/7314/996 60 Simian_virus_40 R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 60/2223 72/10654 8.072181178694e-30 1.031701632553081e-28 4.612674959253714e-29 5718/1017/5689/9134/5684/5720/11065/5682/5700/122706/7321/5707/5690/5717/9491/23198/898/143471/5706/5705/10197/8881/7316/10213/5709/5695/890/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/990/5699/5710/5702/8900/5719/5704/6233/5716/51343/7311/29882/5694/5693/5721/5696/5691/7314/996 60 Simian_virus_40 R-HSA-9013694 Signaling by NOTCH4 65/2223 82/10654 9.828429332704131e-30 1.244316241932919e-28 5.563261886436301e-29 5718/5689/5684/5720/5682/2648/5700/5707/23462/207/5690/3280/5717/9491/6500/5706/5705/10197/10460/7534/7316/10213/5709/9978/5695/5714/9861/5715/22938/8850/5711/5701/5688/1387/5687/4088/5685/5683/5698/5708/59/5692/5686/5713/2033/4855/55294/5699/5710/5702/5719/9794/5704/6233/5716/7311/5694/3516/4851/5693/5663/5721/5696/5691/7314 65 Simian_virus_40 R-HSA-5607764 CLEC7A (Dectin-1) signaling 74/2223 101/10654 1.0181090759256998e-29 1.2769181120488684e-28 5.70902285565813e-29 1147/5718/5689/8945/5684/4773/5720/4790/6885/5682/4772/5700/122706/7321/5707/5336/5690/3553/5717/9491/23198/6500/29108/143471/5706/5705/841/10197/8517/5530/7316/10213/5709/5695/5970/4792/8915/5714/6714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5534/5699/5710/10454/5702/9040/5719/7189/5704/6233/5580/5716/7311/7334/5694/3551/5693/5721/5696/5691/7314 74 Simian_virus_40 R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 51/2223 56/10654 1.537628447678762e-29 1.9106457192452765e-28 8.542380264882012e-29 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/84447/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 51 Simian_virus_40 R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 56/2223 65/10654 1.8858890892945668e-29 2.321892805351659e-28 1.0381040858502204e-28 6118/6917/5434/5440/902/2074/5430/57804/5436/7515/5982/404672/54107/5441/5438/3978/5431/8450/5435/7316/9978/4331/5425/5433/5111/5426/2966/6119/5437/5427/1161/1642/2965/5985/2033/2068/5439/2071/5984/6233/51426/2968/7311/2967/3980/5983/6117/5981/10714/7874/5424/1022/5432/7314/8451/56655 56 Simian_virus_40 R-HSA-1234174 Cellular response to hypoxia 61/2223 75/10654 3.841982898926583e-29 4.687219136690431e-28 2.095627035778136e-28 5718/5689/5684/5720/5682/112399/5700/122706/7321/5707/7422/5690/5717/9491/23198/3091/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/10370/5701/5688/1387/5687/5685/5683/5698/5708/5692/5686/5713/2033/5699/5710/7428/5702/5719/5704/6233/2056/5716/7311/55662/5694/405/5693/5721/5696/5691/768/7314 61 Simian_virus_40 R-HSA-5610783 Degradation of GLI2 by the proteasome 53/2223 60/10654 4.164068630790722e-29 4.989446520108168e-28 2.230751052209315e-28 5718/5689/8945/5684/5720/5682/5700/122706/5707/1452/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 53 Simian_virus_40 R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 53/2223 60/10654 4.164068630790722e-29 4.989446520108168e-28 2.230751052209315e-28 5718/5689/8945/5684/5720/5682/5700/122706/5707/1452/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 53 Simian_virus_40 R-HSA-6782135 Dual incision in TC-NER 56/2223 66/10654 9.946202028348284e-29 1.1812215152250795e-27 5.2811692185920105e-28 6118/6917/5434/5440/902/2074/5430/57804/5436/5982/404672/54107/5441/7507/5438/5431/2072/8450/5435/7316/9978/4331/5425/5433/5111/5426/2966/6119/5437/5427/1161/1642/2965/5985/2033/2068/5439/2071/5984/6233/2067/51426/2968/7311/2967/5983/6117/5981/10714/7874/5424/1022/5432/7314/8451/56655 56 Simian_virus_40 R-HSA-6783783 Interleukin-10 signaling 45/2223 47/10654 1.1455259176959423e-28 1.3485050715332934e-27 6.029083777347064e-28 729230/3557/7124/2208/3592/1437/3587/6351/3593/3553/1230/2919/5743/941/6367/3383/6349/3576/2357/2920/3976/6352/6774/1435/6348/1440/3627/7133/3606/6364/7132/3552/942/3716/6363/6347/7076/3588/7850/7297/3569/1234/3586/5724/3554 45 Simian_virus_40 R-HSA-2871837 FCERI mediated NF-kB activation 64/2223 82/10654 1.3905558465570844e-28 1.622718213982267e-27 7.2550739820369625e-28 1147/5718/5689/8945/5684/5720/4790/6885/5682/5700/122706/7321/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/8517/7316/10213/5709/5695/5970/4792/8915/5714/9861/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/10454/5702/5719/7189/5704/6233/5716/7311/7334/5694/3551/5693/5721/5696/5691/7314 64 Simian_virus_40 R-HSA-180585 Vif-mediated degradation of APOBEC3G 49/2223 54/10654 3.0306749587560874e-28 3.5061774091816114e-27 1.5675904959083212e-27 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 49 Simian_virus_40 R-HSA-376176 Signaling by ROBO receptors 118/2223 218/10654 1.0209344823558803e-27 1.1710205771979413e-26 5.235561447978873e-27 6158/5718/5689/6138/6144/25/55740/6203/5684/9349/4736/7852/8861/5720/6206/6194/6191/6128/5682/51121/6132/2817/6147/10298/6129/6217/5700/122706/5707/6222/6152/5690/6136/5578/6125/5717/9491/23198/6154/51065/6141/26986/143471/6202/5706/5705/10197/6232/6160/23122/7316/6155/10213/5709/6175/9978/6218/5695/6209/5714/6714/6231/6229/9861/6130/5715/6142/5711/6204/5701/5688/5687/5685/1605/5683/5698/5708/51466/5692/5686/5713/7408/140801/6156/5699/6143/5710/6181/6124/5702/998/6207/5719/5704/6233/5716/7311/6223/3921/6188/6189/6135/6201/5694/23332/9045/6187/6168/5693/6208/5721/6137/5696/5691/6122/7314/6387/6230 118 Simian_virus_40 R-HSA-169911 Regulation of Apoptosis 48/2223 53/10654 1.3411165743099518e-27 1.5252359684101316e-26 6.81923681852518e-27 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 48 Simian_virus_40 R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 64/2223 84/10654 1.6293974938789356e-27 1.8375222157861612e-26 8.215449548969423e-27 9318/6118/902/57804/7515/5982/404672/54107/6613/7507/7336/86/3978/2072/8450/7316/9978/4331/5425/5111/5426/1643/2966/6119/7341/10401/5427/1642/2965/5985/142/2068/10987/2071/5984/1069/7329/6233/2067/51426/2873/2968/7311/2967/6612/3980/60/5887/5983/6117/7334/5981/10038/10714/5424/1022/5886/7508/7314/51138/8451/8554/7528/56655 64 Simian_virus_40 R-HSA-5658442 Regulation of RAS by GAPs 56/2223 68/10654 2.1920918208624498e-27 2.4514893529978398e-26 1.0960459104312248e-26 5718/5689/5684/4893/5720/5682/153090/5700/122706/5707/5690/5717/9491/23198/143471/5706/5921/5705/10197/8452/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/3845/5694/3265/4763/5693/5721/5696/5691/7314 56 Simian_virus_40 R-HSA-4641257 Degradation of AXIN 49/2223 55/10654 2.220030770437201e-27 2.4622159453939865e-26 1.1008417043490252e-26 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/8312/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 49 Simian_virus_40 R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 41/2223 42/10654 3.124236012038297e-27 3.4366596132421264e-26 1.5365095141171953e-26 6118/80010/83990/7516/5888/5892/9156/5883/1763/7486/10111/675/5982/545/472/580/11073/116028/641/10635/7517/6119/3364/10524/4683/144715/5889/5985/84126/1111/5984/79728/672/5932/7156/5890/5983/6117/5884/5810/83695 41 Simian_virus_40 R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 46/2223 50/10654 3.199595734768666e-27 3.4909410374467886e-26 1.5607784072042273e-26 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/2209/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/5694/5693/5721/5696/5691/4360 46 Simian_virus_40 R-HSA-5387390 Hh mutants abrogate ligand secretion 51/2223 59/10654 4.554735977498634e-27 4.92939974338965e-26 2.2039045052412747e-26 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/84447/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 51 Simian_virus_40 R-HSA-983705 Signaling by the B Cell Receptor (BCR) 76/2223 112/10654 6.0349804535682044e-27 6.479155014950825e-26 2.896790617712738e-26 1147/5718/5689/8945/5684/4893/4773/5720/4790/6885/5579/5966/5682/4772/5700/122706/5707/5336/5690/5717/9491/23198/6500/930/143471/5706/5705/10197/8517/5530/7316/10213/5709/5695/5970/4792/4793/8915/5714/9861/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/5534/5699/5710/5702/2280/5478/5719/5704/6233/2885/5716/7311/3845/5694/3265/3551/933/5693/5721/5696/5691/7314 76 Simian_virus_40 R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 55/2223 67/10654 8.824738381613342e-27 9.399046752480242e-26 4.20225637219683e-26 5718/5689/5684/5720/11065/5682/5700/122706/7321/5707/991/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/9232/5704/6233/5716/7311/29882/5694/5693/5721/5696/5691/7314/996 55 Simian_virus_40 R-HSA-69231 Cyclin D associated events in G1 42/2223 44/10654 1.1563031567863987e-26 1.21231159094324e-25 5.420171047436244e-26 25/894/1019/902/1029/7027/1027/6500/5925/5934/7316/1869/1875/4331/1026/5933/6714/1871/1031/5519/4067/3717/6502/1021/1874/595/5520/896/1870/6233/1032/28227/1030/7311/7029/5518/1163/1022/1028/7314/5515/5516 42 Simian_virus_40 R-HSA-69236 G1 Phase 42/2223 44/10654 1.1563031567863987e-26 1.21231159094324e-25 5.420171047436244e-26 25/894/1019/902/1029/7027/1027/6500/5925/5934/7316/1869/1875/4331/1026/5933/6714/1871/1031/5519/4067/3717/6502/1021/1874/595/5520/896/1870/6233/1032/28227/1030/7311/7029/5518/1163/1022/1028/7314/5515/5516 42 Simian_virus_40 R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 84/2223 134/10654 5.348495642917033e-26 5.564093916895084e-25 2.487672392054434e-25 1147/5718/5689/3725/8945/5684/5601/4893/4773/5290/5720/5335/4790/6885/5682/4772/5700/122706/7321/5707/5336/5690/5594/5717/4214/9491/23198/6500/143471/5706/5705/10197/8517/5530/7316/10213/5709/5695/5970/4792/8915/5714/9861/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5602/5692/5686/5713/5534/5699/5710/10454/5702/5719/7189/5609/5704/6233/2885/5716/2353/7311/3845/5599/7334/5694/3265/3551/5693/5721/5696/5691/7314/5595 84 Simian_virus_40 R-HSA-5683057 MAPK family signaling cascades 141/2223 294/10654 7.746296001050391e-26 7.996560948776634e-25 3.5752135389463343e-25 5718/2308/5689/27161/3725/5684/2674/3562/4893/5720/1437/2309/5682/1844/2904/3561/5525/5747/153090/5700/10642/3815/122706/5707/5526/10048/5690/57690/5594/5717/9491/3315/23198/27327/5908/3568/143471/5706/2064/5921/5705/10197/3337/1438/192670/8550/8452/5528/7316/10213/5709/9978/1950/3560/5695/4233/983/5597/5714/6714/4609/9861/5715/5037/5519/5711/5701/5688/5159/3567/5687/3558/3717/2247/5685/5683/5698/5708/5692/5686/5713/2335/5699/5529/5710/2264/8555/5702/192669/998/2066/5894/8556/896/5719/3563/1741/23112/5704/6233/5527/2885/3716/5716/2246/7514/7311/8826/5154/5518/5155/2243/2252/1956/60/5536/1843/4343/3570/3845/5694/3265/3559/26523/369/4763/7297/8202/3569/5693/5721/5696/5691/5245/7529/5156/7314/3572/5595/5515/5516 141 Simian_virus_40 R-HSA-8943724 Regulation of PTEN gene transcription 51/2223 61/10654 1.1827777056455394e-25 1.2116699854781022e-24 5.417302468605524e-25 1912/3725/6591/8841/5468/1822/23186/2146/389541/5978/9112/9219/8535/51564/6045/5594/84232/80012/5931/1911/1108/57167/2122/7101/10014/1958/5928/84733/57459/54815/23512/57332/6009/6615/3066/3065/7157/1107/23028/10542/2475/55004/57504/1386/8726/648/23466/53615/57521/6015/5595 51 Simian_virus_40 R-HSA-167172 Transcription of the HIV genome 57/2223 73/10654 1.3232387673426424e-25 1.345292746798353e-24 6.014721669739284e-25 6884/6875/2963/6917/5434/5440/902/5430/6874/5436/6878/404672/6749/5441/5438/5431/7469/5435/6872/4331/5433/8148/2966/6879/9150/2962/54457/5437/8812/83860/2965/905/2068/5439/2071/6873/6827/2968/1025/6881/2967/51616/6880/6908/11198/904/6883/7936/6829/51497/6882/138474/1022/5432/8178/6877/25920 57 Simian_virus_40 R-HSA-5358346 Hedgehog ligand biogenesis 53/2223 65/10654 1.4149496406483372e-25 1.42771610357148e-24 6.383231461571446e-25 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/84447/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/2262/5719/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/5034/7314 53 Simian_virus_40 R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 38/2223 39/10654 3.3315556404613845e-25 3.336528111566551e-24 1.4917413315498735e-24 6118/80010/83990/7516/5888/5892/9156/5883/1763/7486/10111/675/5982/545/472/580/11073/116028/641/6119/3364/10524/4683/144715/5889/5985/84126/1111/5984/672/5932/7156/5890/5983/6117/5884/5810/83695 38 Simian_virus_40 R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 53/2223 66/10654 5.740333382804824e-25 5.706316592388204e-24 2.5512592812465885e-24 5718/5689/5684/5720/5682/112399/5700/122706/7321/5707/5690/5717/9491/23198/3091/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/7428/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 53 Simian_virus_40 R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 45/2223 51/10654 7.78522559875159e-25 7.682185848179878e-24 3.434658352390407e-24 5718/5689/5684/1728/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/5694/5693/5721/5696/5691 45 Simian_virus_40 R-HSA-109606 Intrinsic Pathway for Apoptosis 46/2223 53/10654 1.0930509964950418e-24 1.0707112680995227e-23 4.787084656182665e-24 23368/27113/596/10018/7531/1029/7027/842/7532/207/10971/5594/7533/2810/841/7534/1869/8655/6774/54205/4836/5366/598/56616/836/10000/5534/3002/7157/90427/8626/208/7161/7029/840/331/581/5599/7159/57099/637/317/140735/7529/578/5595 46 Simian_virus_40 R-HSA-5696400 Dual Incision in GG-NER 39/2223 41/10654 1.1524564115540575e-24 1.1207221045692356e-23 5.0106800502350334e-24 6118/57804/5982/404672/54107/7507/2072/8450/7316/9978/5425/5111/5426/1643/2966/6119/5427/1642/2965/5985/142/2068/2071/5984/6233/2067/51426/2968/7311/2967/5983/6117/5981/10038/10714/5424/7314/8451/56655 39 Simian_virus_40 R-HSA-5678895 Defective CFTR causes cystic fibrosis 50/2223 61/10654 2.1386437232643253e-24 2.0647912781444064e-23 9.231555639989894e-24 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Simian_virus_40 R-HSA-73893 DNA Damage Bypass 43/2223 48/10654 2.1959486846602536e-24 2.104973667724329e-23 9.411208648543945e-24 6118/124739/57804/7320/5982/54107/9636/7706/8450/7316/9978/11201/5425/5111/5426/9100/10459/7415/6119/51455/5427/1642/5429/5985/25898/7398/5984/9246/57599/6233/51426/7311/7318/5983/6117/5981/10714/5424/5980/7314/51514/8451/56655 43 Simian_virus_40 R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 51/2223 63/10654 2.234945186649754e-24 2.1271605960879218e-23 9.510405049573422e-24 5718/5689/5684/5720/11065/5682/5700/7321/5707/5690/5717/9491/5706/5705/10197/8881/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/51343/7311/29882/5694/5693/5721/5696/5691/7314/996 51 Simian_virus_40 R-HSA-4615885 SUMOylation of DNA replication proteins 41/2223 45/10654 5.660136306605617e-24 5.34922741089066e-23 2.391606890115049e-23 23165/7150/5905/5903/55706/7175/55143/9631/9212/51588/3619/7153/348995/79023/6613/57122/23636/332/10762/23511/53371/6790/5111/23279/4927/9688/79902/9883/7341/10401/23225/8086/7329/9972/6612/7155/8021/6396/129401/55746/8480 41 Simian_virus_40 R-HSA-5632684 Hedgehog 'on' state 61/2223 85/10654 6.509243103908338e-24 6.10867429751398e-23 2.731150952688814e-23 57154/5718/5689/5684/5720/2735/5682/6608/5700/122706/5707/22873/1452/5690/5717/9491/23198/143471/5706/5705/10197/8452/7316/10213/5709/9978/5695/5727/8650/5714/9861/5715/8405/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/83737/5719/5704/6233/5716/374654/7311/6469/5694/5693/5721/5696/5691/7314 61 Simian_virus_40 R-HSA-5685938 HDR through Single Strand Annealing (SSA) 36/2223 37/10654 7.454279633929328e-24 6.946974492175804e-23 3.1059498474705537e-23 6118/80010/25/5893/83990/5888/9156/5883/1763/7486/10111/5982/545/472/580/11073/2072/116028/641/6119/3364/10524/4683/144715/5985/84126/5984/2067/672/5932/7156/5983/6117/5884/5810/83695 36 Simian_virus_40 R-HSA-167161 HIV Transcription Initiation 42/2223 47/10654 9.574015342250618e-24 8.508826880331344e-23 3.80424450685455e-23 6884/6875/2963/5434/5440/902/5430/6874/5436/6878/404672/5441/5438/5431/5435/6872/4331/5433/8148/2966/6879/2962/54457/5437/83860/2965/2068/5439/2071/6873/2968/6881/2967/51616/6880/6908/6883/6882/138474/1022/5432/6877 42 Simian_virus_40 R-HSA-167162 RNA Polymerase II HIV Promoter Escape 42/2223 47/10654 9.574015342250618e-24 8.508826880331344e-23 3.80424450685455e-23 6884/6875/2963/5434/5440/902/5430/6874/5436/6878/404672/5441/5438/5431/5435/6872/4331/5433/8148/2966/6879/2962/54457/5437/83860/2965/2068/5439/2071/6873/2968/6881/2967/51616/6880/6908/6883/6882/138474/1022/5432/6877 42 Simian_virus_40 R-HSA-73762 RNA Polymerase I Transcription Initiation 42/2223 47/10654 9.574015342250618e-24 8.508826880331344e-23 3.80424450685455e-23 5434/5440/902/9015/2648/2074/9112/9219/9014/25885/404672/5931/54700/5441/51082/5435/7270/4331/9013/7343/1108/2966/8850/5928/5437/57459/2965/54815/64425/2068/3066/3065/2071/1107/2968/57504/84172/2967/6908/53615/1022/10919 42 Simian_virus_40 R-HSA-73776 RNA Polymerase II Promoter Escape 42/2223 47/10654 9.574015342250618e-24 8.508826880331344e-23 3.80424450685455e-23 6884/6875/2963/5434/5440/902/5430/6874/5436/6878/404672/5441/5438/5431/5435/6872/4331/5433/8148/2966/6879/2962/54457/5437/83860/2965/2068/5439/2071/6873/2968/6881/2967/51616/6880/6908/6883/6882/138474/1022/5432/6877 42 Simian_virus_40 R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 42/2223 47/10654 9.574015342250618e-24 8.508826880331344e-23 3.80424450685455e-23 6884/6875/2963/5434/5440/902/5430/6874/5436/6878/404672/5441/5438/5431/5435/6872/4331/5433/8148/2966/6879/2962/54457/5437/83860/2965/2068/5439/2071/6873/2968/6881/2967/51616/6880/6908/6883/6882/138474/1022/5432/6877 42 Simian_virus_40 R-HSA-75953 RNA Polymerase II Transcription Initiation 42/2223 47/10654 9.574015342250618e-24 8.508826880331344e-23 3.80424450685455e-23 6884/6875/2963/5434/5440/902/5430/6874/5436/6878/404672/5441/5438/5431/5435/6872/4331/5433/8148/2966/6879/2962/54457/5437/83860/2965/2068/5439/2071/6873/2968/6881/2967/51616/6880/6908/6883/6882/138474/1022/5432/6877 42 Simian_virus_40 R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 42/2223 47/10654 9.574015342250618e-24 8.508826880331344e-23 3.80424450685455e-23 6884/6875/2963/5434/5440/902/5430/6874/5436/6878/404672/5441/5438/5431/5435/6872/4331/5433/8148/2966/6879/2962/54457/5437/83860/2965/2068/5439/2071/6873/2968/6881/2967/51616/6880/6908/6883/6882/138474/1022/5432/6877 42 Simian_virus_40 R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 40/2223 44/10654 2.5080086655040287e-23 2.214307650727899e-22 9.900034205936956e-23 23368/834/27113/79370/9540/8793/55240/58484/3486/355/55367/472/8794/332/64065/5366/124446/8797/84883/147923/5876/1387/51499/843/94241/7157/8626/604/63970/7161/839/581/7159/637/317/10397/8795/665/5875/27166 40 Simian_virus_40 R-HSA-1638091 Heparan sulfate/heparin (HS-GAG) metabolism 46/2223 55/10654 2.8797648612597797e-23 2.525911401183415e-22 1.1293195534352078e-22 9951/10675/633/8509/126792/2132/6385/2817/375790/64132/3339/1634/9957/6383/9653/3340/222537/9956/266722/64579/1462/27087/9394/9953/9955/135152/1463/26035/221914/2262/9348/64131/1464/11285/2239/60495/10855/64711/6382/90161/9672/2719/26229/10082/63827/2131 46 Simian_virus_40 R-HSA-2559583 Cellular Senescence 103/2223 195/10654 3.166676221812832e-23 2.759532136151182e-22 1.2337699565504538e-22 1912/1017/7014/3725/25913/9134/1019/5601/11065/4790/5606/3159/7290/1029/7027/7321/2146/10111/8535/6045/57690/5594/1027/27327/80012/898/5931/7295/5925/7013/1051/50488/472/79813/192670/3576/8550/8881/29855/7316/2114/1869/890/6774/5970/1026/1911/26277/6667/1871/4194/1031/5598/3552/5928/1432/10524/84733/4683/5602/65057/23512/1021/57332/6195/25842/192669/7157/8900/23135/8091/23112/5609/1870/6233/1032/2353/1030/51343/6196/7311/7029/57634/4343/8726/6197/29882/5599/648/5600/23466/4217/26523/3456/2113/3569/10919/7314/23523/996/6015/5595/4193 103 Simian_virus_40 R-HSA-5688426 Deubiquitination 137/2223 297/10654 4.220199959067664e-23 3.6538763516572937e-22 1.6336257906068378e-22 9960/5718/23358/5689/5684/8295/5720/3607/10617/221937/6885/5682/90865/2648/79594/5700/10474/122706/7321/5707/991/8237/4738/7375/5690/55611/2625/9817/4303/51720/5717/9491/57646/23198/63967/4086/1080/330/3091/143471/5706/5705/4287/27005/10197/7706/8517/86/580/7416/29086/8239/7316/10213/5709/993/5695/890/25862/4792/983/84132/5714/4092/8678/2099/9100/1643/79589/4609/7415/9861/4194/4089/5715/27430/64127/8850/7128/5711/5701/5688/329/5687/6502/7347/4088/5685/5683/5698/5708/5692/5686/5713/2033/5728/5699/8312/5710/10454/5702/7157/8900/9958/4087/63891/5719/7189/57599/5704/6233/5716/672/7311/55593/367/6881/79184/51616/78990/60/7040/5887/7345/1540/5694/9736/7874/5693/10254/5721/5696/5691/5886/7314/4193/7528 137 Simian_virus_40 R-HSA-1236974 ER-Phagosome pathway 59/2223 83/10654 7.994918869287407e-23 6.8776802067844235e-22 3.074968795879772e-22 1147/3135/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10333/10197/7099/8517/4615/7316/10213/5709/5695/7096/567/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/7097/3551/3105/5693/5721/5696/5691/7314 59 Simian_virus_40 R-HSA-5621481 C-type lectin receptors (CLRs) 83/2223 142/10654 8.754339312763606e-23 7.483008508107489e-22 3.3456073806739897e-22 1147/5718/5689/8945/5684/4893/4773/5720/4790/6885/5682/4772/5700/122706/7321/5707/5336/5690/3553/4582/5717/9491/23198/6500/29108/143471/5706/5705/841/10197/8517/5530/7316/10213/5709/5695/5970/4792/8915/5714/6714/9861/5715/5711/5701/5688/1387/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/2033/5534/5699/5710/10454/5702/9040/5894/5719/7189/5704/6233/5580/30835/5716/7311/3845/7334/5694/3265/3551/5693/5721/5696/5691/7314 83 Simian_virus_40 R-HSA-168325 Viral Messenger RNA Synthesis 39/2223 43/10654 1.108466838898428e-22 9.355738979884846e-22 4.1828937316921816e-22 23165/2963/5434/5440/5903/55706/7175/9631/5430/5436/348995/79023/57122/5441/23636/5438/10762/5431/23511/5435/53371/5433/23279/4927/9688/79902/2962/9883/5437/23225/5439/8086/9972/8021/6396/129401/5432/55746/8480 39 Simian_virus_40 R-HSA-5696395 Formation of Incision Complex in GG-NER 39/2223 43/10654 1.108466838898428e-22 9.355738979884846e-22 4.1828937316921816e-22 6118/902/404672/6613/7507/7336/2072/8450/7316/9978/4331/1643/2966/6119/7341/10401/1642/2965/142/2068/2071/1069/7329/6233/2067/2968/7311/2967/6612/5887/6117/7334/10038/1022/5886/7508/7314/8451/8554 39 Simian_virus_40 R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 67/2223 102/10654 1.1374198249853599e-22 9.540108782064705e-22 4.2653243436951e-22 7124/1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/330/143471/5706/5705/10197/10673/7316/10213/5709/5695/970/7292/7133/5714/9861/5715/5711/7132/5701/5688/329/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/4049/5704/6233/5716/944/7311/958/8784/5694/5693/5721/5696/5691/939/959/7314 67 Simian_virus_40 R-HSA-4608870 Asymmetric localization of PCP proteins 50/2223 64/10654 1.2492048774892503e-22 1.0412626991245801e-21 4.6554219036866465e-22 57154/5718/5689/5684/5720/5682/5700/122706/5707/1856/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Simian_virus_40 R-HSA-674695 RNA Polymerase II Pre-transcription Events 59/2223 84/10654 2.1465713089013787e-22 1.7782090719417593e-21 7.950264107042144e-22 6884/6875/2963/6917/5434/5440/902/6830/5430/6874/5436/6878/404672/6749/5441/5438/5431/7469/5435/6872/4331/5433/8148/2966/6879/9150/2962/54457/5437/8812/83860/2965/905/2068/5439/2071/6873/6827/2968/1025/6881/2967/51616/6880/6908/11198/904/6883/7936/6829/51497/6882/138474/1022/5432/8178/55840/6877/25920 59 Simian_virus_40 R-HSA-202424 Downstream TCR signaling 64/2223 98/10654 1.6541201897361006e-21 1.361858462960642e-20 6.0887859744887146e-21 1147/5718/5689/8945/5684/5290/5720/4790/6885/5682/5700/122706/7321/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/8517/7316/10213/5709/5695/5970/4792/8915/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5728/5699/5710/5702/5719/7189/5704/6233/5716/7311/7334/5694/3551/5693/5721/5696/5691/7314 64 Simian_virus_40 R-HSA-5689880 Ub-specific processing proteases 108/2223 220/10654 5.0869941428425735e-21 4.162650085179716e-20 1.8610954181131368e-20 9960/5718/23358/5689/5684/8295/5720/6885/5682/90865/2648/79594/5700/10474/122706/5707/991/8237/7375/5690/55611/2625/9817/4303/5717/9491/57646/23198/63967/4086/1080/330/3091/143471/5706/5705/27005/10197/8517/7416/8239/7316/10213/5709/993/5695/890/25862/4792/84132/5714/4092/8678/9100/1643/79589/4609/9861/4194/4089/5715/27430/5711/5701/5688/329/5687/6502/4088/5685/5683/5698/5708/5692/5686/5713/5728/5699/8312/5710/10454/5702/7157/8900/9958/4087/63891/5719/7189/57599/5704/6233/5716/7311/367/6881/51616/1540/5694/9736/7874/5693/10254/5721/5696/5691/7314/4193 108 Simian_virus_40 R-HSA-351202 Metabolism of polyamines 46/2223 59/10654 7.478441773872154e-21 6.082465976082685e-20 2.719433372317147e-20 5718/5689/5684/1728/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/6303/5694/5693/5721/5696/5691 46 Simian_virus_40 R-HSA-195258 RHO GTPase Effectors 142/2223 327/10654 7.828291687738666e-21 6.32865508731644e-20 2.8295030196645786e-20 220134/5905/55839/11130/25/79682/5590/5903/10403/54908/6249/55143/5579/4638/1499/55055/25936/5525/9735/7531/5747/80776/1783/1058/4659/991/1856/401541/79019/5526/4627/51807/2316/7532/10971/348235/80152/4771/5578/9212/5594/1063/8379/1027/3619/79172/1080/7533/2810/147841/7277/348995/23421/55920/79023/57122/79980/64105/6232/7534/332/1780/23122/5528/3688/5048/1781/5501/57405/10398/8655/4085/10552/81624/6279/6714/23279/55166/79902/3796/54821/5519/9183/7456/1432/81565/2491/1062/699/7846/999/51466/22919/1060/91687/995/79003/5529/51143/998/23028/83540/11004/5527/2885/5580/701/9055/7514/9184/9928/367/8826/10499/5518/10383/54820/5347/57551/60/5300/84790/84643/6396/5600/23332/25909/64946/9793/10726/10109/81930/55746/140735/7280/5500/7529/4221/5595/5515/1778/5516 142 Simian_virus_40 R-HSA-5656169 Termination of translesion DNA synthesis 31/2223 32/10654 1.7307587491221853e-20 1.390825294204774e-19 6.218294907025816e-20 6118/124739/57804/5982/54107/9636/7706/7316/11201/5425/5111/5426/9100/6119/51455/5427/5429/5985/5984/9246/6233/51426/7311/7318/5983/6117/5981/10714/5424/7314/56655 31 Simian_virus_40 R-HSA-1236975 Antigen processing-Cross presentation 63/2223 99/10654 2.602282777329684e-20 2.07872826617645e-19 9.293867061891729e-20 1147/3135/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/2209/143471/5706/5705/10333/10197/7099/8517/4615/7316/10213/5709/5695/7096/567/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/1520/5716/7311/5694/7097/3551/3105/5693/5721/5696/5691/7314/4360/1514 63 Simian_virus_40 R-HSA-5684996 MAPK1/MAPK3 signaling 118/2223 255/10654 3.5246544522829407e-020 2.7988676183217197e-19 1.251356610277967e-19 5718/5689/5684/2674/3562/4893/5720/1437/5682/1844/2904/3561/5525/5747/153090/5700/3815/122706/5707/5526/10048/5690/5594/5717/9491/23198/5908/3568/143471/5706/2064/5921/5705/10197/1438/8452/5528/7316/10213/5709/9978/1950/3560/5695/4233/983/5714/6714/9861/5715/5037/5519/5711/5701/5688/5159/3567/5687/3558/3717/2247/5685/5683/5698/5708/5692/5686/5713/2335/5699/5529/5710/2264/5702/2066/5894/5719/3563/1741/5704/6233/5527/2885/3716/5716/2246/7311/8826/5154/5518/5155/2243/2252/1956/60/5536/1843/3570/3845/5694/3265/3559/369/4763/7297/3569/5693/5721/5696/5691/5245/7529/5156/7314/3572/5595/5515/5516 118 Simian_virus_40 R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 35/2223 39/10654 4.113759951899926e-20 3.2474505032057065e-19 1.4519152771411504e-19 6118/124739/57804/5982/54107/9636/7706/7316/11201/5425/5111/5426/9100/10459/7415/6119/51455/5427/5429/5985/25898/5984/9246/6233/51426/7311/7318/5983/6117/5981/10714/5424/5980/7314/56655 35 Simian_virus_40 R-HSA-9614085 FOXO-mediated transcription 48/2223 65/10654 5.922953590237344e-20 4.648306267893868e-19 2.0782293299078402e-19 2308/27113/857/2290/2309/57060/10018/4802/7532/207/10971/4303/23410/1027/7295/2810/4287/6720/7534/847/5934/4800/1026/901/4089/8850/1647/9314/10370/1387/4088/2908/10628/10000/6794/2033/4801/3630/3066/3065/6648/4087/208/604/23411/25942/7529/10891 48 Simian_virus_40 R-HSA-2022928 HS-GAG biosynthesis 30/2223 31/10654 8.124026678017384e-20 6.338630117383331e-19 2.833962794657227e-19 9951/8509/2132/6385/2817/375790/3339/9957/6383/9653/3340/222537/9956/266722/64579/9394/9953/9955/26035/221914/2262/9348/2239/64711/6382/90161/9672/2719/10082/2131 30 Simian_virus_40 R-HSA-72689 Formation of a pool of free 40S subunits 63/2223 101/10654 1.1936416178436044e-19 9.259347116451545e-19 4.1397975185327317e-19 6158/6138/6144/6203/9349/4736/6206/6194/6191/6128/51121/6132/6147/8666/6129/6217/6222/6152/6136/8668/8667/6125/6154/51065/8662/6141/10480/6202/6232/6160/6155/6175/6218/6209/6231/6229/6130/6142/6204/140801/6156/6143/6181/6124/6207/6233/7311/6223/3646/51386/3921/6188/6189/8665/6135/6201/9045/6187/6168/6208/6137/6122/6230 63 Simian_virus_40 R-HSA-3232142 SUMOylation of ubiquitinylation proteins 34/2223 38/10654 1.7919503200648855e-19 1.3820674307626876e-18 6.1791390347065015e-19 23165/5903/55706/7175/9631/51588/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/7341/23225/7428/8086/7329/5987/5371/9972/9063/8021/6396/129401/55746/8480/4193/8554 34 Simian_virus_40 R-HSA-113418 Formation of the Early Elongation Complex 31/2223 33/10654 2.284984979497723e-19 1.732457538127652e-18 7.745711794907536e-19 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/7469/5435/4331/5433/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/2967/7936/6829/51497/1022/5432/25920 31 Simian_virus_40 R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 31/2223 33/10654 2.284984979497723e-19 1.732457538127652e-18 7.745711794907536e-19 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/7469/5435/4331/5433/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/2967/7936/6829/51497/1022/5432/25920 31 Simian_virus_40 R-HSA-2559585 Oncogene Induced Senescence 31/2223 33/10654 2.284984979497723e-19 1.732457538127652e-18 7.745711794907536e-19 1019/1029/7027/57690/5594/27327/5925/192670/7316/2114/1869/6667/1871/4194/1031/1021/192669/7157/23112/1870/6233/1032/1030/7311/7029/4343/26523/2113/7314/5595/4193 31 Simian_virus_40 R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 29/2223 30/10654 3.8080661433502583e-19 2.871025148525869e-18 1.2836178011293007e-18 6118/57804/7320/5982/54107/8450/7316/9978/5425/5111/5426/6119/5427/1642/5985/7398/5984/57599/6233/7311/5983/6117/5981/10714/5424/7314/51514/8451/56655 29 Simian_virus_40 R-HSA-5610787 Hedgehog 'off' state 67/2223 113/10654 4.2061838436477733e-19 3.15346297104766e-18 1.409894025803723e-18 5718/5689/8945/5684/5720/2735/5682/6608/5700/122706/5707/1452/5690/5717/9491/23198/6500/7277/143471/5706/5705/10197/7316/10213/5709/9978/5695/5727/8650/5714/9861/5715/5711/2932/5701/5688/5687/7846/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/83737/5719/5704/6233/5716/374654/7311/80199/10383/23322/84790/5694/8481/5693/5721/5696/7280/5691/7314 67 Simian_virus_40 R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 39/2223 48/10654 4.92013820509048e-19 3.668236372906347e-18 1.6400460683634934e-18 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/4331/5433/2966/9150/2962/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/8178/25920 39 Simian_virus_40 R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 66/2223 111/10654 6.284697671103873e-19 4.6597040191278435e-18 2.0833251948410628e-18 6158/6138/6144/6203/9349/4736/6206/6194/6191/6128/51121/6132/6147/8666/6129/6217/6222/6152/6136/8668/8667/6125/6154/51065/8662/6141/10480/26986/6202/6232/6160/6155/6175/6218/6209/6231/6229/6130/6142/6204/8894/140801/6156/6143/6181/6124/6207/6233/7311/6223/3646/51386/3921/6188/6189/8665/6135/6201/9045/6187/6168/6208/6137/1974/6122/6230 66 Simian_virus_40 R-HSA-202403 TCR signaling 69/2223 119/10654 6.868663488879988e-19 5.064695825317002e-18 2.2643945567736226e-18 1147/5718/5689/8945/55740/5684/5290/5720/5335/4790/6885/5682/5700/122706/7321/5707/5690/5717/9491/23198/6500/143471/5706/5705/5788/10197/8517/7316/10213/5709/5695/5970/4792/8915/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/51466/5692/5686/5713/7408/5728/5699/5710/5702/5719/7189/5704/6233/5716/7311/7334/5694/3551/5693/5721/5696/5691/7314 69 Simian_virus_40 R-HSA-9607240 FLT3 Signaling 119/2223 267/10654 1.0275893438806104e-18 7.53565518845781e-18 3.3691453897724932e-18 54106/5718/5689/5684/2674/3562/4893/5290/5720/1437/5682/1844/2904/3561/5525/5747/153090/5700/3815/122706/5707/5526/10048/5690/5594/5717/9491/23198/5908/3568/143471/5706/2064/5921/5705/10197/1438/8452/6776/5528/7316/10213/5709/9978/1950/3560/5695/4233/5714/6714/9861/5715/5037/5519/5711/5701/5688/5159/3567/5687/3558/3717/2247/5685/5683/5698/5708/5692/5686/5713/2335/5699/5529/5710/2264/5702/2066/5894/5719/3563/1741/208/5704/6233/5527/2885/3716/5716/2246/7311/8826/5154/5518/5155/2243/2252/1956/60/5536/1843/3845/2549/6777/5694/3265/3559/369/4763/5693/5721/5696/5691/5245/7529/5156/7314/5595/5515/5516 119 Simian_virus_40 R-HSA-156902 Peptide chain elongation 57/2223 89/10654 1.0738130989780916e-18 7.83183249363369e-18 3.5015644531894294e-18 6158/6138/6144/6203/9349/4736/6206/6194/6191/6128/51121/6132/1938/6147/6129/1915/6217/6222/6152/6136/6125/6154/51065/6141/6202/6232/6160/6155/6175/6218/6209/6231/6229/6130/6142/6204/140801/6156/6143/6181/6124/6207/6233/7311/6223/3921/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/6230 57 Simian_virus_40 R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 66/2223 112/10654 1.2227510937523337e-18 8.869902528733145e-18 3.965679222980542e-18 6158/6138/6144/6203/9349/4736/6206/6194/6191/6128/51121/6132/6147/8666/6129/6217/6222/6152/6136/8668/8667/6125/6154/51065/8662/6141/10480/6202/6232/6160/6155/6175/6218/9669/6209/6231/6229/6130/6142/6204/8894/140801/6156/6143/6181/6124/6207/6233/7311/6223/3646/51386/3921/6188/6189/8665/6135/6201/9045/6187/6168/6208/6137/1974/6122/6230 66 Simian_virus_40 R-HSA-5673001 RAF/MAP kinase cascade 113/2223 249/10654 1.4585541603433861e-18 1.0523546683767871e-17 4.7050134204625364e-18 5718/5689/5684/2674/3562/4893/5720/1437/5682/1844/2904/3561/5525/5747/153090/5700/3815/122706/5707/5526/10048/5690/5594/5717/9491/23198/5908/3568/143471/5706/2064/5921/5705/10197/1438/8452/5528/7316/10213/5709/9978/1950/3560/5695/4233/5714/6714/9861/5715/5037/5519/5711/5701/5688/5159/3567/5687/3558/3717/2247/5685/5683/5698/5708/5692/5686/5713/2335/5699/5529/5710/2264/5702/2066/5894/5719/3563/1741/5704/6233/5527/2885/3716/5716/2246/7311/8826/5154/5518/5155/2243/2252/1956/60/5536/1843/3845/5694/3265/3559/369/4763/5693/5721/5696/5691/5245/7529/5156/7314/5595/5515/5516 113 Simian_virus_40 R-HSA-1971475 A tetrasaccharide linker sequence is required for GAG synthesis 26/2223 26/10654 1.797286147653046e-18 1.2898171177274802e-17 5.766693521881431e-18 10675/633/126792/6385/2817/375790/64132/3339/1634/6383/1462/27087/135152/1463/221914/2262/64131/1464/11285/2239/6382/9672/2719/26229/10082/63827 26 Simian_virus_40 R-HSA-4570464 SUMOylation of RNA binding proteins 38/2223 47/10654 1.9437118302186537e-18 1.387479402209273e-17 6.2033356283574056e-18 1912/23165/5903/55706/7175/9631/8535/6045/80012/348995/79023/6613/57122/23636/10762/23511/53371/3190/1911/23279/4927/9688/79902/9883/7341/84733/23225/57332/8086/7329/9972/8021/6396/648/129401/55746/8480/6015 38 Simian_virus_40 R-HSA-5693537 Resolution of D-Loop Structures 31/2223 34/10654 2.0721488158865665e-18 1.4713352967829482e-17 6.578250209163703e-18 51750/80010/83990/7516/5888/5892/9156/1763/7486/10111/675/472/80198/580/116028/197342/641/10635/7517/84464/10524/4683/5889/23514/79728/146956/672/5932/7156/5890/348654 31 Simian_virus_40 R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 55/2223 85/10654 2.1724201632818856e-18 1.5184311766272347e-17 6.788813010255893e-18 1147/3725/8945/5601/351/81793/4790/6885/5606/5594/4214/6500/8517/4615/7100/5528/7316/5970/4792/4793/3146/5519/64127/5598/1432/4208/23291/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 55 Simian_virus_40 R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 55/2223 85/10654 2.1724201632818856e-18 1.5184311766272347e-17 6.788813010255893e-18 1147/3725/8945/5601/351/81793/4790/6885/5606/5594/4214/6500/8517/4615/7100/5528/7316/5970/4792/4793/3146/5519/64127/5598/1432/4208/23291/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 55 Simian_virus_40 R-HSA-975871 MyD88 cascade initiated on plasma membrane 55/2223 85/10654 2.1724201632818856e-18 1.5184311766272347e-17 6.788813010255893e-18 1147/3725/8945/5601/351/81793/4790/6885/5606/5594/4214/6500/8517/4615/7100/5528/7316/5970/4792/4793/3146/5519/64127/5598/1432/4208/23291/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/7314/5595/5515/5516 55 Simian_virus_40 R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 58/2223 93/10654 3.446112927346975e-18 2.3838574992266187e-17 1.0658081218598892e-17 54106/1147/3665/3725/8945/5601/351/4790/6885/5606/5594/4214/6500/7099/8517/4615/5528/7316/5970/4792/4793/3146/5519/64127/5598/1432/4208/23291/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/51311/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/51284/7314/5595/5515/5516 58 Simian_virus_40 R-HSA-975155 MyD88 dependent cascade initiated on endosome 58/2223 93/10654 3.446112927346975e-18 2.3838574992266187e-17 1.0658081218598892e-17 54106/1147/3665/3725/8945/5601/351/4790/6885/5606/5594/4214/6500/7099/8517/4615/5528/7316/5970/4792/4793/3146/5519/64127/5598/1432/4208/23291/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/51311/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/51284/7314/5595/5515/5516 58 Simian_virus_40 R-HSA-72613 Eukaryotic Translation Initiation 68/2223 119/10654 3.642574026142368e-18 2.4940481342260498e-17 1.1150736814721536e-17 6158/6138/6144/6203/9349/4736/6206/6194/6191/6128/51121/6132/6147/8666/6129/6217/6222/6152/6136/8668/8667/6125/6154/51065/8662/6141/10480/26986/6202/6232/6160/6155/6175/6218/9669/6209/6231/6229/6130/6142/6204/8894/140801/6156/6143/6181/6124/6207/6233/7311/6223/3646/51386/3921/6188/6189/8665/6135/6201/1978/9045/6187/6168/6208/6137/1974/6122/6230 68 Simian_virus_40 R-HSA-72737 Cap-dependent Translation Initiation 68/2223 119/10654 3.642574026142368e-18 2.4940481342260498e-17 1.1150736814721536e-17 6158/6138/6144/6203/9349/4736/6206/6194/6191/6128/51121/6132/6147/8666/6129/6217/6222/6152/6136/8668/8667/6125/6154/51065/8662/6141/10480/26986/6202/6232/6160/6155/6175/6218/9669/6209/6231/6229/6130/6142/6204/8894/140801/6156/6143/6181/6124/6207/6233/7311/6223/3646/51386/3921/6188/6189/8665/6135/6201/1978/9045/6187/6168/6208/6137/1974/6122/6230 68 Simian_virus_40 R-HSA-168898 Toll-like Receptor Cascades 81/2223 155/10654 3.732457512997861e-18 2.542618265199558e-17 1.1367890902531557e-17 54106/1147/3665/3725/8945/5601/351/81793/4790/6885/5606/7184/7321/5336/3684/5594/6271/4214/6500/8411/330/10333/841/7099/8517/4615/7098/7100/338/5528/7316/5970/4792/7096/4793/6279/8651/3146/5519/64127/5598/1432/4208/329/23291/5602/3656/6195/57162/10454/6288/3661/3654/7189/6285/5609/6233/51311/1520/1385/81622/2353/6196/7311/5518/2243/1386/6197/5599/5600/7334/7097/3551/57161/51231/51284/7314/5595/5515/1514/5516 81 Simian_virus_40 R-HSA-167169 HIV Transcription Elongation 37/2223 46/10654 7.638852181599847e-18 5.125669813853497e-17 2.2916556544799544e-17 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/4331/5433/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/8178/25920 37 Simian_virus_40 R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 37/2223 46/10654 7.638852181599847e-18 5.125669813853497e-17 2.2916556544799544e-17 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/4331/5433/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/8178/25920 37 Simian_virus_40 R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 37/2223 46/10654 7.638852181599847e-18 5.125669813853497e-17 2.2916556544799544e-17 2963/6917/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/7469/5435/4331/5433/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/8178/25920 37 Simian_virus_40 R-HSA-69205 G1/S-Specific Transcription 27/2223 28/10654 8.329970936557461e-18 5.561602486000055e-17 2.4865584885246155e-17 8318/7027/898/286826/5934/5422/1869/1875/1876/983/5933/5111/4998/5928/91750/990/1874/81620/3065/8900/7298/55957/7029/1719/7083/132660/6241 27 Simian_virus_40 R-HSA-5619084 ABC transporter disorders 51/2223 77/10654 8.419649795897577e-18 5.593648527769578e-17 2.5008860779893794e-17 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/335/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Simian_virus_40 R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 25/2223 25/10654 8.691244068882746e-18 5.745640167704752e-17 2.5688406114924375e-17 6118/57804/7515/5982/54107/3978/7316/5425/5111/5426/6119/5427/5985/5984/6233/51426/7311/3980/5983/6117/5981/10714/5424/7314/56655 25 Simian_virus_40 R-HSA-5693568 Resolution of D-loop Structures through Holliday Junction Intermediates 30/2223 33/10654 9.157550037761321e-18 6.024231446409654e-17 2.6933970699298005e-17 80010/83990/7516/5888/5892/9156/1763/7486/10111/675/472/80198/580/116028/197342/641/10635/7517/84464/10524/4683/5889/23514/79728/146956/672/5932/7156/5890/348654 30 Simian_virus_40 R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 59/2223 97/10654 1.0006744636274426e-17 6.550756732624526e-17 2.928803308177881e-17 54106/1147/3665/3725/8945/5601/351/4790/6885/5606/5594/4214/6500/8411/7099/8517/4615/5528/7316/5970/4792/4793/3146/5519/64127/5598/1432/4208/23291/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/51311/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/51284/7314/5595/5515/5516 59 Simian_virus_40 R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 57/2223 92/10654 1.051292186111501e-17 6.848709290105021e-17 3.062016076052916e-17 54106/1147/3725/8945/5601/351/4790/6885/5606/5594/4214/6500/7099/8517/4615/5528/7316/5970/4792/4793/3146/5519/64127/5598/1432/4208/23291/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/51311/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/57161/51231/51284/7314/5595/5515/5516 57 Simian_virus_40 R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 58/2223 95/10654 1.4752357128455774e-17 9.518107339609446e-17 4.2554876332083966e-17 1147/3725/8945/5601/351/4790/6885/5606/5594/4214/6500/10333/7099/8517/4615/5528/7316/5970/4792/7096/4793/8651/3146/5519/64127/5598/1432/4208/23291/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/7097/3551/57161/51231/7314/5595/5515/5516 58 Simian_virus_40 R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 58/2223 95/10654 1.4752357128455774e-17 9.518107339609446e-17 4.2554876332083966e-17 1147/3725/8945/5601/351/4790/6885/5606/5594/4214/6500/10333/7099/8517/4615/5528/7316/5970/4792/7096/4793/8651/3146/5519/64127/5598/1432/4208/23291/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/7097/3551/57161/51231/7314/5595/5515/5516 58 Simian_virus_40 R-HSA-5693607 Processing of DNA double-strand break ends 59/2223 98/10654 2.009299196901485e-17 1.2901815895893746e-16 5.768323053305698e-17 1017/6118/80010/54962/83990/9156/5883/1763/7486/10111/51588/51720/5982/63967/5531/51548/545/472/6613/7336/580/11073/29086/7316/116028/890/641/9656/6119/3364/7341/10524/4683/144715/5985/165918/84126/8914/1111/8900/5984/7329/8924/6233/672/5932/7158/7311/6047/9025/79184/7156/5983/6117/7334/5884/5810/83695/7314 59 Simian_virus_40 R-HSA-114452 Activation of BH3-only proteins 28/2223 30/10654 2.140476866815322e-17 1.3678666453648393e-16 6.11564819090092e-17 23368/27113/596/10018/7531/7027/7532/207/10971/7533/2810/7534/1869/8655/5366/10000/5534/7157/90427/8626/208/7161/7029/5599/7159/637/140735/7529 28 Simian_virus_40 R-HSA-156842 Eukaryotic Translation Elongation 57/2223 93/10654 2.170203600624698e-17 1.3802906312977936e-16 6.17119507286644e-17 6158/6138/6144/6203/9349/4736/6206/6194/6191/6128/51121/6132/1938/6147/6129/1915/6217/6222/6152/6136/6125/6154/51065/6141/6202/6232/6160/6155/6175/6218/6209/6231/6229/6130/6142/6204/140801/6156/6143/6181/6124/6207/6233/7311/6223/3921/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/6230 57 Simian_virus_40 R-HSA-157118 Signaling by NOTCH 106/2223 235/10654 2.97764866398003e-17 1.8849077863496228e-16 8.427307539566122e-17 5718/5689/27161/3725/5684/8841/2208/5720/79885/5682/2648/9734/892/7027/5700/5707/23462/207/51564/4904/5690/57690/3280/5717/9491/6500/27327/3091/51548/10013/5706/5705/10197/10460/192670/7534/7316/10213/5709/9978/1950/1869/4854/9611/5695/8650/9612/1024/5714/6772/4609/1871/9861/10014/5715/22938/8850/5711/5701/5688/1387/5687/4088/5685/5683/5698/5708/59/5692/5686/5713/2033/4855/595/55294/5699/5710/3002/5702/192669/3066/3065/7157/83737/5719/23112/9794/5704/6233/5716/1385/7311/7029/1956/4343/9787/5694/26523/3516/4851/5693/5663/5721/5696/5691/7314 106 Simian_virus_40 R-HSA-1538133 G0 and Early G1 26/2223 27/10654 3.886690482307975e-17 2.4487974775855877e-16 1.0948423893825282e-16 1017/9134/4605/7027/7153/898/286826/5934/1869/1875/993/890/983/5933/5111/4609/5928/91750/990/1874/3065/8900/55957/7029/1859/132660 26 Simian_virus_40 R-HSA-69190 DNA strand elongation 29/2223 32/10654 4.033930456561837e-17 2.5296890993953203e-16 1.1310085392229452e-16 4172/6118/2237/8318/1763/57804/5982/4173/3978/5557/5422/4174/5425/84515/5111/4171/6119/5985/4175/5984/51659/23649/5983/6117/5981/10714/5558/5424/4176 29 Simian_virus_40 R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 24/2223 24/10654 4.201360820928767e-17 2.6224308007843746e-16 1.172472787235935e-16 6118/2237/1763/57804/5982/54107/3978/5557/5422/5425/5111/5426/6119/5427/5985/5984/23649/5983/6117/5981/10714/5558/5424/56655 24 Simian_virus_40 R-HSA-192823 Viral mRNA Translation 55/2223 89/10654 4.663910054008281e-17 2.8976700428144043e-16 1.295530570557856e-16 6158/6138/6144/6203/9349/4736/6206/6194/6191/6128/51121/6132/6147/6129/6217/6222/6152/6136/6125/6154/51065/6141/6202/6232/6160/6155/6175/6218/6209/6231/6229/6130/6142/6204/140801/6156/6143/6181/6124/6207/6233/7311/6223/3921/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/6230 55 Simian_virus_40 R-HSA-5689603 UCH proteinases 60/2223 102/10654 5.169422675023971e-17 3.1969425022498476e-16 1.4293334585319737e-16 5718/5689/5684/5720/3607/221937/5682/5700/122706/5707/4738/5690/5717/9491/23198/143471/5706/5705/10197/86/580/7316/10213/5709/5695/5714/4092/9861/5715/5711/5701/5688/5687/7347/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9958/5719/5704/6233/5716/7311/60/7040/7345/5694/5693/5721/5696/5691/7314/7528 60 Simian_virus_40 R-HSA-4085377 SUMOylation of SUMOylation proteins 30/2223 34/10654 6.229805920182161e-17 3.835045662791037e-16 1.7146254826189435e-16 23165/5903/55706/7175/9631/51588/348995/79023/6613/57122/23636/10762/23511/10210/53371/23279/4927/9688/79902/9883/7341/23225/8086/7329/9972/8021/6396/129401/55746/8480 30 Simian_virus_40 R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 40/2223 54/10654 6.394424140603713e-17 3.9184096788539646e-16 1.7518970248229352e-16 9318/6917/5434/5440/902/2074/5430/5436/404672/5441/7507/5438/5431/8450/5435/7316/9978/4331/5433/2966/5437/1161/1642/2965/2033/2068/5439/10987/2071/6233/2873/2968/7311/2967/7874/1022/5432/7314/51138/8451 40 Simian_virus_40 R-HSA-4086400 PCP/CE pathway 56/2223 92/10654 6.504888106779962e-17 3.967981745135776e-16 1.7740603927581712e-16 57154/5718/5689/5684/5720/5579/5682/5700/122706/5707/1856/5690/1212/5578/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/1213/1211/5694/5693/5721/5696/6259/5691/7314 56 Simian_virus_40 R-HSA-177243 Interactions of Rev with host cellular proteins 31/2223 36/10654 8.359381048339595e-17 5.076149034783591e-16 2.269515216743781e-16 23165/5905/3837/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/7514/9972/8021/6396/129401/1104/55746/8480 31 Simian_virus_40 R-HSA-69473 G2/M DNA damage checkpoint 57/2223 95/10654 8.801635944542725e-17 5.320628575484836e-16 2.378820525552088e-16 6118/80010/83990/9156/5883/1763/7531/7486/10111/7532/10971/51588/51720/5982/7533/2810/11200/545/472/7336/7534/580/11073/29086/891/116028/983/641/9656/6119/3364/7341/10524/4683/144715/5985/995/165918/84126/1111/7157/5984/8924/672/5932/7158/9025/79184/7156/5983/6117/7334/7465/5884/5810/83695/7529 57 Simian_virus_40 R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 58/2223 98/10654 1.1587926432932577e-16 6.942409496873e-16 3.1039088659640834e-16 1147/3725/8945/5601/351/4790/6885/5606/5594/4214/6500/10333/7099/8517/4615/5528/7316/5970/4792/7096/4793/8651/3146/5519/64127/5598/1432/4208/23291/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/7097/3551/57161/51231/7314/5595/5515/5516 58 Simian_virus_40 R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 58/2223 98/10654 1.1587926432932577e-16 6.942409496873e-16 3.1039088659640834e-16 1147/3725/8945/5601/351/4790/6885/5606/5594/4214/6500/10333/7099/8517/4615/5528/7316/5970/4792/7096/4793/8651/3146/5519/64127/5598/1432/4208/23291/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/7097/3551/57161/51231/7314/5595/5515/5516 58 Simian_virus_40 R-HSA-8939211 ESR-mediated signaling 101/2223 223/10654 1.2042383760806163e-16 7.182612892000831e-16 3.2113023362149772e-016 27161/3725/2354/2963/3838/596/5434/5440/5590/4893/857/5290/5241/2309/5747/7031/5430/207/5436/2625/57690/5594/1027/3315/27327/10274/51523/4318/5441/10735/5481/192670/5438/5431/5885/2100/5435/4313/1950/865/5469/1655/4314/5433/6667/6714/2099/4609/2962/7391/8850/8503/10524/1387/5437/10000/3320/2033/8243/4846/9126/595/2783/4602/8312/5439/192669/3065/2066/23028/23112/208/10498/3326/7514/1385/1025/2353/10499/23030/1386/6908/1956/5536/4343/3845/904/3276/7392/3265/26523/8202/5432/8648/3480/2288/2773/10728/5595/7528/6387 101 Simian_virus_40 R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 25/2223 26/10654 1.8104019209962732e-16 1.0750262734411498e-15 4.8063767814060355e-016 51750/80010/83990/7516/5888/5892/9156/1763/7486/10111/675/472/580/116028/641/10635/7517/10524/4683/5889/79728/672/5932/7156/5890 25 Simian_virus_40 R-HSA-5358351 Signaling by Hedgehog 76/2223 149/10654 2.4258221019776677e-16 1.4341203792308504e-15 6.411864586725114e-16 57154/5718/5689/8945/5684/5720/2735/5682/6608/5700/122706/5707/22873/1452/5690/5717/9491/23198/6500/7277/143471/5706/5705/10197/8452/84447/7316/10213/5709/9978/5695/5727/8650/5714/7415/9861/5715/8405/5711/2932/5701/5688/5687/7846/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/2262/83737/5719/5704/6233/5716/374654/7311/80199/10383/6469/23322/84790/5694/8481/5693/5721/5696/7280/5691/5034/7314 76 Simian_virus_40 R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 56/2223 94/10654 2.582714876723743e-16 1.5201769142821332e-15 6.796618096641429e-16 1147/3665/3725/8945/5601/351/4790/6885/5606/7321/5594/6500/330/841/8517/7098/5528/7316/5970/4792/4793/3146/5519/64127/5598/1432/4208/329/23291/5602/3656/6195/10454/6288/3661/3654/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595/5515/5516 56 Simian_virus_40 R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 29/2223 33/10654 2.664070248925846e-16 1.5544270756776024e-15 6.949748475458729e-16 23165/3303/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/7514/9972/8021/6396/129401/3304/55746/8480 29 Simian_virus_40 R-HSA-180746 Nuclear import of Rev protein 29/2223 33/10654 2.664070248925846e-16 1.5544270756776024e-15 6.949748475458729e-16 23165/3837/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/9972/8021/6396/129401/1104/55746/8480 29 Simian_virus_40 R-HSA-1169408 ISG15 antiviral mechanism 47/2223 72/10654 3.930535166014651e-16 2.2834537631132733e-15 1.0209182249388703e-15 23165/3837/3838/5903/5335/55706/7175/9631/348995/9636/79023/57122/23636/7706/10762/9470/23511/7316/53371/6772/23279/4927/9688/79902/3840/9883/23225/3661/8086/9246/51191/6233/3716/7311/9972/7318/5610/5300/8021/6396/129401/7334/55746/1974/8480/7314/5595 47 Simian_virus_40 R-HSA-3899300 SUMOylation of transcription cofactors 35/2223 45/10654 4.1770729658571847e-16 2.4162206552501473e-15 1.0802774911699615e-15 1912/1487/3622/8535/6045/51588/4869/80012/6613/10210/28996/1655/9612/1911/7341/1387/84733/10401/1616/2033/57332/7329/115426/10155/10499/6612/9063/25942/6294/648/11315/8648/10891/6015/8554 35 Simian_virus_40 R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 56/2223 95/10654 5.027403897418471e-16 2.8956120301869476e-15 1.2946104456871598e-15 6158/6138/6144/6203/9349/4736/6206/6194/6191/6128/51121/6132/6147/6129/6217/6222/6152/6136/6125/6154/51065/6141/26986/6202/6232/6160/6155/6175/6218/6209/6231/6229/6130/6142/6204/140801/6156/6143/6181/6124/6207/6233/7311/6223/3921/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/6230 56 Simian_virus_40 R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 50/2223 80/10654 6.410123162888281e-16 3.67623302760516e-15 1.6436213238175078e-15 23165/3837/3838/5903/5335/55706/7175/9631/2316/348995/9636/79023/57122/23636/7706/10762/9470/23511/7316/53371/6772/23279/4927/9688/79902/6041/3840/9883/6059/23225/3661/8086/9246/51191/6233/3716/7311/9972/7318/5610/5300/8021/6396/129401/7334/55746/1974/8480/7314/5595 50 Simian_virus_40 R-HSA-2408557 Selenocysteine synthesis 55/2223 93/10654 7.523147898053769e-16 4.277993423384813e-15 1.9126647198441784e-15 6158/6138/6144/6203/9349/4736/6206/6194/6191/6128/51121/6132/6147/6129/6217/6222/6152/6136/6125/6154/51065/6141/6202/6232/6160/6155/6175/6218/6209/6231/6229/6130/6142/6204/140801/6156/6143/6181/6124/6207/6233/7311/6223/3921/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/6230 55 Simian_virus_40 R-HSA-72764 Eukaryotic Translation Termination 55/2223 93/10654 7.523147898053769e-16 4.277993423384813e-15 1.9126647198441784e-15 6158/6138/6144/6203/9349/4736/6206/6194/6191/6128/51121/6132/6147/6129/6217/6222/6152/6136/6125/6154/51065/6141/6202/6232/6160/6155/6175/6218/6209/6231/6229/6130/6142/6204/140801/6156/6143/6181/6124/6207/6233/7311/6223/3921/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/6230 55 Simian_virus_40 R-HSA-4551638 SUMOylation of chromatin organization proteins 46/2223 71/10654 1.2514289264454854e-15 7.086150292362199e-15 3.1681744973303428e-15 1912/23165/23468/5903/55706/7175/83746/9631/8535/6045/80012/348995/79023/6613/57122/23636/10762/23511/53371/1911/23279/4927/9688/79902/9883/7341/84733/23225/23512/57332/3066/3065/1107/8086/7329/9972/6612/9063/8021/6396/648/129401/55746/8480/6015/8554 46 Simian_virus_40 R-HSA-165054 Rev-mediated nuclear export of HIV RNA 29/2223 34/10654 1.450239025899005e-15 8.177398204859097e-15 3.656064771173963e-15 23165/5905/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/7514/9972/8021/6396/129401/1104/55746/8480 29 Simian_virus_40 R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 34/2223 44/10654 1.5781831828741961e-15 8.861597620992348e-15 3.9619661494749696e-15 892/7027/7321/6497/8239/7316/1875/9611/9612/1024/6667/5933/4092/4609/4089/22938/8812/4088/1874/142/905/3065/6498/4087/6233/1025/1030/7311/25937/7029/904/7314/4221/5054 34 Simian_virus_40 R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 25/2223 27/10654 1.958206283056426e-15 1.0904202621832878e-14 4.875202364455832e-15 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/4331/5433/2966/2962/5437/2965/2068/5439/2071/2968/2967/6829/1022/5432 25 Simian_virus_40 R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 25/2223 27/10654 1.958206283056426e-15 1.0904202621832878e-14 4.875202364455832e-15 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/4331/5433/2966/2962/5437/2965/2068/5439/2071/2968/2967/6829/1022/5432 25 Simian_virus_40 R-HSA-3858494 Beta-catenin independent WNT signaling 73/2223 146/10654 3.7383606495883015e-15 2.0730909056807856e-14 9.2686627675743e-15 57154/5718/5689/27161/5684/5720/6885/5579/5682/1499/51701/4772/5700/122706/5707/1856/5690/1212/5578/57690/5717/9491/23198/27327/143471/5706/5705/10197/192670/2775/5530/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5534/5699/2783/5710/5702/192669/5719/23112/5704/6233/5716/7311/1213/1211/4343/3845/5694/26523/5693/5721/5696/6259/5691/7314 73 Simian_virus_40 R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 27/2223 31/10654 4.807644012441745e-15 2.655085705636552e-14 1.1870725956646284e-14 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/7514/9972/8021/6396/129401/55746/8480 27 Simian_virus_40 R-HSA-170834 Signaling by TGF-beta Receptor Complex 46/2223 73/10654 5.986718196887372e-15 3.2926950082880546e-14 1.4721438189067305e-14 57154/5590/892/7027/7321/6497/10273/4738/8239/7316/1875/9611/5501/9612/1024/6667/5933/4092/4609/4089/22938/8812/4088/1874/142/905/3065/2280/6498/9958/9040/4087/5499/6233/7514/1025/1030/7311/25937/7029/7040/904/5500/7314/4221/5054 46 Simian_virus_40 R-HSA-166166 MyD88-independent TLR4 cascade 56/2223 99/10654 6.253753895906725e-15 3.4116007025637497e-14 1.525305828269933e-14 1147/3665/3725/8945/5601/351/4790/6885/5606/7321/5594/6500/330/841/7099/8517/5528/7316/5970/4792/4793/3146/5519/64127/5598/1432/4208/329/23291/5602/3656/6195/10454/6288/3661/3654/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595/5515/5516 56 Simian_virus_40 R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 56/2223 99/10654 6.253753895906725e-15 3.4116007025637497e-14 1.525305828269933e-14 1147/3665/3725/8945/5601/351/4790/6885/5606/7321/5594/6500/330/841/7099/8517/5528/7316/5970/4792/4793/3146/5519/64127/5598/1432/4208/329/23291/5602/3656/6195/10454/6288/3661/3654/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595/5515/5516 56 Simian_virus_40 R-HSA-112382 Formation of RNA Pol II elongation complex 41/2223 61/10654 6.5946180462111115e-15 3.5685392814577866e-14 1.5954721079543013e-14 2963/6917/5434/5440/902/6830/5430/5436/404672/6749/5441/5438/5431/7469/5435/4331/5433/2966/9150/2962/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/8178/55840/25920 41 Simian_virus_40 R-HSA-75955 RNA Polymerase II Transcription Elongation 41/2223 61/10654 6.5946180462111115e-15 3.5685392814577866e-14 1.5954721079543013e-14 2963/6917/5434/5440/902/6830/5430/5436/404672/6749/5441/5438/5431/7469/5435/4331/5433/2966/9150/2962/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/2967/11198/904/7936/6829/51497/1022/5432/8178/55840/25920 41 Simian_virus_40 R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 29/2223 35/10654 6.772726894328415e-15 3.650200599272584e-14 1.631982384175522e-14 23165/5903/55706/7175/9631/91754/348995/79023/9133/57122/23636/10762/23511/891/53371/983/23279/4927/9688/79902/9883/23225/8086/9972/8021/6396/129401/55746/8480 29 Simian_virus_40 R-HSA-176187 Activation of ATR in response to replication stress 30/2223 37/10654 7.0921230897381234e-15 3.791884138019347e-14 1.695328228622659e-14 1017/4172/6118/8318/5883/5982/63967/4173/545/4174/993/84515/4171/4998/6119/3364/144715/5985/990/995/84126/4175/1111/5984/55388/5983/6117/5884/5810/4176 30 Simian_virus_40 R-HSA-6806003 Regulation of TP53 Expression and Degradation 30/2223 37/10654 7.0921230897381234e-15 3.791884138019347e-14 1.695328228622659e-14 1017/1029/207/11200/472/117584/639/7316/890/80196/983/4194/5519/1616/10000/900/7157/8900/208/6233/5527/2475/7311/5518/7874/51230/7314/4193/5515/5516 30 Simian_virus_40 R-HSA-5628897 TP53 Regulates Metabolic Genes 51/2223 86/10654 7.292907145158672e-15 3.883762455874182e-14 1.736406463133017e-14 27161/5563/27165/83667/7531/389541/7532/207/10971/9997/2936/57690/51422/7249/27327/7295/7533/2810/53632/27244/192670/7534/2539/54205/143686/5571/2821/10000/2877/10128/5728/6009/54541/192669/7157/8626/23112/208/10542/2475/55004/5562/4343/50484/26523/5564/5052/5565/57521/7529/7296 51 Simian_virus_40 R-HSA-2980766 Nuclear Envelope Breakdown 37/2223 52/10654 8.129577065635937e-15 4.312210443511236e-14 1.927962940467021e-14 4000/23165/5903/55706/7175/5579/9631/91754/5578/348995/79023/9133/57122/23636/7443/10762/23511/891/53371/983/23279/4927/9688/79902/9883/23225/7444/8086/2010/9972/5347/8021/6396/129401/55746/7112/8480 37 Simian_virus_40 R-HSA-450294 MAP kinase activation 42/2223 64/10654 1.1150131979787222e-14 5.891132723178919e-14 2.6338894440442256e-14 1147/3725/8945/5601/4790/6885/5606/5594/6500/8517/5528/7316/5519/64127/5598/1432/4208/23291/5602/3656/6195/10454/3654/7189/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595/5515/5516 42 Simian_virus_40 R-HSA-5619115 Disorders of transmembrane transporters 82/2223 176/10654 1.3135934608317675e-14 6.913107546808753e-14 3.0908081431335703e-14 5718/23165/5689/5684/5903/5720/55706/7175/5682/9631/5700/122706/5707/5690/285195/5717/9491/23198/1080/348995/143471/79023/5706/57122/5705/23636/10197/10762/23511/7316/10213/5709/335/5695/53371/5714/23279/4927/9688/7415/9861/79902/5715/5711/9883/5701/5688/5687/23225/5685/5683/682/5698/5708/5692/5686/5713/5699/5710/5702/8086/6514/5719/5704/6233/5716/7311/9972/8021/6396/129401/213/5694/9197/55746/5693/5721/5696/5691/8480/6513/7314 82 Simian_virus_40 R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 38/2223 55/10654 1.6279522946490554e-14 8.534031169605594e-14 3.815513190583724e-14 1147/834/596/351/4790/6885/842/10910/58484/7295/330/29108/841/8517/7316/5970/24145/64127/7128/1432/329/598/10628/3656/5603/10454/83737/3654/7189/6233/3326/7311/5600/7334/1540/3551/6300/7314 38 Simian_virus_40 R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 66/2223 129/10654 1.8876140074561497e-14 9.8567237276504e-14 4.406880951259493e-14 1147/3665/3725/8945/5601/351/4790/6885/5606/7321/5336/3684/5594/4214/6500/330/10333/841/7099/8517/4615/5528/7316/5970/4792/7096/4793/8651/3146/5519/64127/5598/1432/4208/329/23291/5602/3656/6195/57162/10454/6288/3661/3654/7189/6285/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/7097/3551/57161/51231/7314/5595/5515/5516 66 Simian_virus_40 R-HSA-180786 Extension of Telomeres 26/2223 30/10654 2.027721370785129e-14 1.0547294882145904e-13 4.715631094849137e-14 6118/2237/7015/1763/57804/5982/54107/3978/5557/5422/10856/5425/5111/5426/6119/5427/5985/5984/23649/5983/6117/5981/10714/5558/5424/56655 26 Simian_virus_40 R-HSA-927802 Nonsense-Mediated Decay (NMD) 61/2223 115/10654 2.172550683241993e-14 1.1213703911195211e-13 5.0135784997892154e-14 6158/9887/6138/6144/6203/9349/4736/6206/6194/6191/6128/51121/6132/6147/6129/6217/6222/6152/6136/6125/6154/51065/6141/26986/6202/6232/6160/6155/6175/6218/6209/6231/6229/6130/6142/6204/140801/6156/6143/6181/6124/5520/6207/6233/23381/7311/6223/5518/3921/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/5515/6230 61 Simian_virus_40 R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 61/2223 115/10654 2.172550683241993e-14 1.1213703911195211e-13 5.0135784997892154e-14 6158/9887/6138/6144/6203/9349/4736/6206/6194/6191/6128/51121/6132/6147/6129/6217/6222/6152/6136/6125/6154/51065/6141/26986/6202/6232/6160/6155/6175/6218/6209/6231/6229/6130/6142/6204/140801/6156/6143/6181/6124/5520/6207/6233/23381/7311/6223/5518/3921/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/5515/6230 61 Simian_virus_40 R-HSA-168253 Host Interactions with Influenza Factors 32/2223 42/10654 2.2069666295263592e-14 1.1347698148752391e-13 5.0734865046582965e-14 23165/3837/3838/5903/55706/7175/9631/348995/9636/79023/57122/23636/10762/23511/293/53371/23279/4927/9688/79902/3840/9883/23225/8086/9972/5610/8021/7040/6396/129401/55746/8480 32 Simian_virus_40 R-HSA-3560783 Defective B4GALT7 causes EDS, progeroid type 20/2223 20/10654 2.285898812171914e-14 1.1576136626168712e-13 5.175619952087353e-14 10675/633/6385/2817/375790/3339/1634/6383/1462/1463/221914/2262/1464/11285/2239/6382/9672/2719/10082/63827 20 Simian_virus_40 R-HSA-3560801 Defective B3GAT3 causes JDSSDHD 20/2223 20/10654 2.285898812171914e-14 1.1576136626168712e-13 5.175619952087353e-14 10675/633/6385/2817/375790/3339/1634/6383/1462/1463/221914/2262/1464/2239/6382/9672/2719/26229/10082/63827 20 Simian_virus_40 R-HSA-4420332 Defective B3GALT6 causes EDSP2 and SEMDJL1 20/2223 20/10654 2.285898812171914e-14 1.1576136626168712e-13 5.175619952087353e-14 10675/633/126792/6385/2817/375790/3339/1634/6383/1462/1463/221914/2262/1464/2239/6382/9672/2719/10082/63827 20 Simian_virus_40 R-HSA-69186 Lagging Strand Synthesis 20/2223 20/10654 2.285898812171914e-14 1.1576136626168712e-13 5.175619952087353e-14 6118/2237/1763/57804/5982/3978/5557/5422/5425/5111/6119/5985/5984/23649/5983/6117/5981/10714/5558/5424 20 Simian_virus_40 R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 27/2223 32/10654 2.4643584579988843e-14 1.2432966355768808e-13 5.558703288719289e-14 892/7027/7316/1875/1024/6667/5933/4092/4609/4089/22938/8812/4088/1874/905/3065/4087/6233/1025/1030/7311/25937/7029/904/7314/4221/5054 27 Simian_virus_40 R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 30/2223 38/10654 2.6966689205731103e-14 1.3554043788049116e-13 6.05993015859126e-14 1912/6595/6597/1459/8535/6045/80012/1460/6598/6599/86/865/28996/1457/1911/6603/51412/84733/6604/8289/2033/6605/6602/57332/57492/648/6601/23466/23429/6015 30 Simian_virus_40 R-HSA-167287 HIV elongation arrest and recovery 29/2223 36/10654 2.7886749067564163e-14 1.3860747129137448e-13 6.197055348347592e-14 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/7469/5435/5433/9150/2962/5437/8812/905/5439/6827/1025/11198/904/7936/6829/51497/5432/8178/25920 29 Simian_virus_40 R-HSA-167290 Pausing and recovery of HIV elongation 29/2223 36/10654 2.7886749067564163e-14 1.3860747129137448e-13 6.197055348347592e-14 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/7469/5435/5433/9150/2962/5437/8812/905/5439/6827/1025/11198/904/7936/6829/51497/5432/8178/25920 29 Simian_virus_40 R-HSA-6804757 Regulation of TP53 Degradation 29/2223 36/10654 2.7886749067564163e-14 1.3860747129137448e-13 6.197055348347592e-14 1017/1029/207/11200/472/117584/7316/890/80196/983/4194/5519/1616/10000/900/7157/8900/208/6233/5527/2475/7311/5518/7874/51230/7314/4193/5515/5516 29 Simian_virus_40 R-HSA-8951664 Neddylation 99/2223 234/10654 5.363272722991659e-14 2.655908484964873e-13 1.1874404552749062e-13 9318/5718/5689/8945/5684/5720/11091/23363/5682/23038/25879/5700/122706/7321/5707/9021/4738/5690/9817/5717/5929/9491/23198/6500/5931/3091/143471/5706/28952/5705/26259/10197/332/26263/8452/8450/7316/10213/5709/9978/5695/55958/5714/26272/7704/1643/9861/5715/5711/5701/5688/5687/26270/1161/6502/7347/23291/5685/5683/5698/5708/1642/5692/5686/23113/5713/55294/5699/10238/5710/10987/7428/5702/9040/5719/80176/5704/6233/2873/5716/25793/7311/23194/83987/90293/80204/51667/5694/23014/5693/5721/5696/5691/9820/7314/51514/10537/51138/8451 99 Simian_virus_40 R-HSA-3247509 Chromatin modifying enzymes 111/2223 274/10654 5.5825947559620897e-14 2.7442645283886906e-13 1.2269439024092505e-13 55904/9643/23774/6595/9070/10196/1019/8295/8841/5927/8464/29943/55167/11091/4790/9869/64769/84148/7862/6597/2648/23186/10474/2146/5978/1788/9112/9219/51147/6839/6871/5929/23569/5931/6598/117143/79813/6599/86/7403/9611/2874/84289/10856/5970/11143/9612/29072/6603/51412/10933/1108/5926/2122/27097/84444/8850/5928/10524/1387/27154/56950/57459/3717/6604/8289/54815/2033/23512/6605/6602/595/7994/3066/3065/9682/1107/79084/23028/23135/55693/10498/57492/22992/57504/80854/6881/58508/10499/23030/57634/1386/6880/51317/10419/60/9739/8726/10902/6883/3276/6601/51230/6187/53615/9913/8648/64754/4297/10765/10919 111 Simian_virus_40 R-HSA-4839726 Chromatin organization 111/2223 274/10654 5.5825947559620897e-14 2.7442645283886906e-13 1.2269439024092505e-13 55904/9643/23774/6595/9070/10196/1019/8295/8841/5927/8464/29943/55167/11091/4790/9869/64769/84148/7862/6597/2648/23186/10474/2146/5978/1788/9112/9219/51147/6839/6871/5929/23569/5931/6598/117143/79813/6599/86/7403/9611/2874/84289/10856/5970/11143/9612/29072/6603/51412/10933/1108/5926/2122/27097/84444/8850/5928/10524/1387/27154/56950/57459/3717/6604/8289/54815/2033/23512/6605/6602/595/7994/3066/3065/9682/1107/79084/23028/23135/55693/10498/57492/22992/57504/80854/6881/58508/10499/23030/57634/1386/6880/51317/10419/60/9739/8726/10902/6883/3276/6601/51230/6187/53615/9913/8648/64754/4297/10765/10919 111 Simian_virus_40 R-HSA-72086 mRNA Capping 25/2223 29/10654 8.507955552684986e-14 4.167035164855201e-13 1.8630559604419679e-13 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/4331/5433/2966/2962/5437/2965/2068/5439/2071/2968/2967/6829/1022/5432 25 Simian_virus_40 R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 26/2223 31/10654 1.0071897612398004e-13 4.915086034850226e-13 2.19750493361411e-13 23165/3837/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/6396/129401/55746/8480 26 Simian_virus_40 R-HSA-201681 TCF dependent signaling in response to WNT 98/2223 233/10654 1.1188058920044456e-13 5.439990967644804e-13 2.4321867217487947e-13 5718/27123/9070/5689/8945/5684/8295/857/5720/7015/1487/6597/5682/1499/5525/864/1459/5700/122706/5707/1856/5526/207/1454/1452/5690/5717/5929/9491/23198/1460/143471/5706/5705/10197/6657/7534/8452/5528/7316/10213/5709/9978/5695/1457/5714/4609/9861/5715/5519/5711/2932/5701/10524/5688/1387/440193/5687/1455/5685/5683/5698/5708/5692/5686/5713/2033/54894/5699/8312/5529/5710/5702/3065/5719/208/57680/5704/6233/5527/5716/7514/23072/7311/5518/331/6659/5694/9736/5693/5721/5696/6259/5691/7314/4221/5515/5516 98 Simian_virus_40 R-HSA-448424 Interleukin-17 signaling 44/2223 72/10654 1.15269306354266e-13 5.584527405322201e-13 2.4968080798757983e-13 3605/1147/3725/8945/5601/4790/6885/5606/5594/6500/8517/5528/7316/5519/64127/5598/1432/4208/23291/5602/3656/6195/10454/3654/7189/112744/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/51231/7314/5595/5515/5516 44 Simian_virus_40 R-HSA-9006931 Signaling by Nuclear Receptors 117/2223 299/10654 2.035716341772137e-13 9.82709111747557e-13 4.3936323923139657e-13 27161/3725/2354/2963/3838/596/5434/5440/5590/4893/8841/857/112724/5290/5241/2309/344/5747/7031/5160/5430/207/5436/10901/2625/57690/5594/1027/3315/27327/10274/51523/4318/5441/10735/8644/126/5481/6720/192670/5438/348/5431/5885/2100/5435/4313/1950/9611/865/5469/2874/1655/4314/127/9612/5433/6667/6714/2099/4609/2962/7391/8850/8503/124/10524/1387/5437/10000/3320/2033/8243/4846/9126/595/2783/4602/8312/5439/192669/3065/9682/2066/23028/23112/208/10498/3326/7514/1385/1025/2353/10499/23030/1386/6908/1956/5536/4343/3845/904/1071/3276/7392/3265/26523/8202/5432/8648/3480/2288/2773/10728/5595/7528/6387 117 Simian_virus_40 R-HSA-168276 NS1 Mediated Effects on Host Pathways 30/2223 40/10654 2.995644926926979e-13 1.440915946930468e-12 6.442247154681674e-13 23165/3837/3838/5903/55706/7175/9631/348995/9636/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/3840/9883/23225/8086/9972/5610/8021/6396/129401/55746/8480 30 Simian_virus_40 R-HSA-983169 Class I MHC mediated antigen processing & presentation 137/2223 371/10654 3.3061342541258955e-13 1.584582917513197e-12 7.084573401698349e-13 57154/1147/3135/5718/23352/5689/8945/5684/5720/11065/5682/7319/5700/122706/7321/5707/991/10273/65264/9021/7320/5690/9817/5717/9491/23198/6500/10533/2209/143471/5706/5705/26259/10333/10197/7099/8517/7336/4615/26263/8881/8452/7316/10213/5709/9978/5695/7317/80196/22872/7096/567/55958/7337/5714/26272/140691/7704/8651/3093/9861/25831/5715/5711/5701/5688/5687/26270/6502/23291/5685/10616/5683/3309/5698/5708/5692/5686/5713/25898/55294/5699/79654/5710/7428/5702/22954/83737/9040/63891/5719/10075/9246/80176/8924/51191/5704/6233/56658/1520/5716/7327/10425/25793/51343/7311/9871/26091/6047/7318/23194/90293/868/80204/29882/57520/6396/7334/5930/5694/7097/4591/3551/23014/7332/3105/5693/5721/5696/23608/55585/5691/9820/7314/996/4360/1514 137 Simian_virus_40 R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 20/2223 21/10654 3.853267873585341e-13 1.8337182575714634e-12 8.198442284224131e-13 6118/2237/328/57804/5982/54107/3978/5425/5111/5426/6119/5427/5985/5984/5983/6117/5981/10714/5424/56655 20 Simian_virus_40 R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 20/2223 21/10654 3.853267873585341e-13 1.8337182575714634e-12 8.198442284224131e-13 7832/4849/4869/4850/9337/10769/25904/246175/4848/23019/28984/995/7157/55571/55835/5325/57472/85456/29883/1263 20 Simian_virus_40 R-HSA-176033 Interactions of Vpr with host cellular proteins 28/2223 36/10654 3.925292786999202e-13 1.8613932580045685e-12 8.32217552013965e-13 23165/5903/55706/7175/9631/3159/348995/79023/57122/23636/10762/23511/293/53371/292/23279/4927/9688/79902/9883/23225/8086/9972/8021/6396/129401/55746/8480 28 Simian_virus_40 R-HSA-6804758 Regulation of TP53 Activity through Acetylation 25/2223 30/10654 4.09091264621843e-13 1.9331002715581456e-12 8.642773196236121e-13 23774/64769/7862/3622/9219/207/5931/84289/1108/29117/5928/27154/57459/10000/54815/2033/7994/3066/3065/7157/1107/5371/208/5300/53615 25 Simian_virus_40 R-HSA-159227 Transport of the SLBP independent Mature mRNA 27/2223 34/10654 4.223884909017532e-13 1.975070922613773e-12 8.830421412580206e-13 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/9972/8021/6396/129401/55746/8480 27 Simian_virus_40 R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 27/2223 34/10654 4.223884909017532e-13 1.975070922613773e-12 8.830421412580206e-13 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/7469/5435/5433/9150/2962/5437/5439/6827/1025/11198/904/7936/6829/51497/5432/8178/25920 27 Simian_virus_40 R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 27/2223 34/10654 4.223884909017532e-13 1.975070922613773e-12 8.830421412580206e-13 2963/6917/5434/5440/5430/5436/6749/5441/5438/5431/7469/5435/5433/9150/2962/5437/5439/6827/1025/11198/904/7936/6829/51497/5432/8178/25920 27 Simian_virus_40 R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs 64/2223 130/10654 4.699034938571059e-13 2.1896197526258198e-012 9.78965612202304e-13 5718/5689/25/5684/8861/5720/902/5682/6929/5700/122706/5707/5690/2625/5717/9491/23198/4005/143471/5706/5705/10197/7316/10213/5709/865/5695/4331/10413/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/6886/4602/5710/5702/83737/5719/5704/6233/5716/7311/6688/7161/5694/1022/5693/5721/4297/5696/5691/7314 64 Simian_virus_40 R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 18/2223 18/10654 5.320502368692246e-13 2.470627743524219e-12 1.104602567894584e-12 7027/25946/2810/5934/891/983/6790/5933/5111/1647/2033/995/1874/7157/10498/7029/581/3276 18 Simian_virus_40 R-HSA-913531 Interferon Signaling 86/2223 199/10654 6.0334455523337285e-013 2.792028941804091e-12 1.2482990797931852e-12 80263/3135/23165/3665/3460/3837/3838/5903/5335/55706/7175/960/9631/3455/2316/9021/54739/9830/23650/348995/9636/2209/79023/3383/57122/23636/7706/10762/3662/9470/23511/7316/53371/3663/567/6672/6772/8651/23279/4927/9688/3659/79902/6041/3840/3459/1958/9883/7341/6059/3717/23225/5771/3458/3454/3661/8086/9246/5371/3439/51191/6233/5580/3716/7311/81603/9972/7318/5610/5300/8021/6396/129401/7334/3456/6773/7297/55746/3105/5696/5724/1974/8480/7314/5595/8554 86 Simian_virus_40 R-HSA-447115 Interleukin-12 family signaling 37/2223 57/10654 7.188440546998164e-13 3.3150815168630705e-12 1.4821526901027141e-12 5055/3592/6627/9049/27250/3593/6775/9446/3595/5908/3313/6175/3185/6774/6772/149233/6950/3717/9466/3458/3181/998/6648/5478/3716/3594/2939/302/51561/4282/246778/7297/5721/3586/5034/829/3572 37 Simian_virus_40 R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 21/2223 23/10654 7.713259507996648e-13 3.544929541003939e-12 1.5849163372595853e-12 2963/5434/5440/5430/5436/5441/5438/5431/7469/5435/5433/9150/2962/5437/5439/6827/7936/6829/51497/5432/25920 21 Simian_virus_40 R-HSA-9018519 Estrogen-dependent gene expression 70/2223 150/10654 1.0415675843659413e-12 4.770592826686325e-12 2.1329029031384464e-12 27161/3725/2354/2963/3838/596/5434/5440/5241/7031/5430/5436/2625/57690/27327/10274/51523/5441/10735/192670/5438/5431/5885/5435/865/5469/1655/5433/6667/2099/4609/2962/7391/8850/10524/1387/5437/3320/2033/8243/9126/595/4602/8312/5439/192669/3065/2066/23028/23112/10498/3326/1025/2353/10499/23030/1386/6908/4343/904/3276/7392/26523/8202/5432/8648/2288/10728/7528/6387 70 Simian_virus_40 R-HSA-73933 Resolution of Abasic Sites (AP sites) 29/2223 39/10654 1.0903005155847724e-12 4.976813918077431e-12 2.225103093030148e-12 11284/6118/2237/328/57804/4913/7515/5982/54107/3978/6996/5425/5111/5426/6119/5427/5985/142/5984/4595/4968/3980/5983/6117/5981/10038/10714/5424/56655 29 Simian_virus_40 R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 118/2223 309/10654 1.14124961855339e-12 5.191718603724234e-12 2.3211856648543524e-12 57154/5718/23352/5689/8945/5684/5720/11065/5682/7319/5700/122706/7321/5707/991/10273/65264/9021/7320/5690/9817/5717/9491/23198/6500/10533/143471/5706/5705/26259/10197/7336/26263/8881/8452/7316/10213/5709/9978/5695/7317/80196/55958/7337/5714/26272/140691/7704/8651/3093/9861/25831/5715/5711/5701/5688/5687/26270/6502/23291/5685/10616/5683/5698/5708/5692/5686/5713/25898/55294/5699/79654/5710/7428/5702/22954/83737/9040/63891/5719/10075/9246/80176/8924/51191/5704/6233/56658/5716/7327/10425/25793/51343/7311/26091/6047/7318/23194/90293/868/80204/29882/57520/7334/5930/5694/4591/23014/7332/5693/5721/5696/23608/55585/5691/9820/7314/996 118 Simian_virus_40 R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 22/2223 25/10654 1.1638158629344853e-12 5.276489486682701e-12 2.3590862086509836e-12 1017/994/902/2305/9133/891/993/890/4331/983/5519/995/5520/8900/28227/7514/5518/5347/7465/1022/5515/5516 22 Simian_virus_40 R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 27/2223 35/10654 1.4803499723678653e-12 6.688988764032576e-12 2.9906060047835665e-12 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/9972/8021/6396/129401/55746/8480 27 Simian_virus_40 R-HSA-180910 Vpr-mediated nuclear import of PICs 26/2223 33/10654 1.6256925614975033e-12 7.321071870904863e-12 3.2732064996594023e-12 23165/5903/55706/7175/9631/3159/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/6396/129401/55746/8480 26 Simian_virus_40 R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 47/2223 84/10654 1.6315575092534235e-12 7.322910292368209e-12 3.2740284466623887e-12 7124/1052/1019/8841/4790/5468/29079/892/9440/6721/1051/90390/6720/6837/3952/688/5465/9611/5469/1050/5970/9612/1024/9314/1387/10001/6604/9439/2033/9967/84246/896/51003/10498/9370/9477/112950/55588/10499/23054/7040/9412/8202/9282/8648/54797/10891 47 Simian_virus_40 R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 25/2223 31/10654 1.6939758000296103e-12 7.552543267906102e-12 3.376695946902878e-12 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/6396/129401/55746/8480 25 Simian_virus_40 R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 25/2223 31/10654 1.6939758000296103e-12 7.552543267906102e-12 3.376695946902878e-12 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/6396/129401/55746/8480 25 Simian_virus_40 R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 19/2223 20/10654 1.7717167817171373e-12 7.87299311610728e-12 3.519967115994313e-12 23368/27113/55240/472/5366/84883/147923/1387/51499/94241/7157/8626/63970/7161/581/7159/637/665/27166 19 Simian_virus_40 R-HSA-5655862 Translesion synthesis by POLK 17/2223 17/10654 2.56546616934631e-12 1.1325182892311672e-11 5.063420071078244e-12 6118/5982/7316/5111/10459/6119/51455/5985/5984/6233/51426/7311/5983/6117/5981/5980/7314 17 Simian_virus_40 R-HSA-5656121 Translesion synthesis by POLI 17/2223 17/10654 2.56546616934631e-12 1.1325182892311672e-11 5.063420071078244e-12 6118/5982/7316/11201/5111/10459/6119/51455/5985/5984/6233/7311/5983/6117/5981/5980/7314 17 Simian_virus_40 R-HSA-382556 ABC-family proteins mediated transport 53/2223 103/10654 5.337944104265576e-12 2.3486954058768537e-11 1.0500873647735559e-11 5718/5689/5684/5720/5682/5700/122706/5707/5243/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/335/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/8894/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 53 Simian_virus_40 R-HSA-110373 Resolution of AP sites via the multiple-nucleotide patch replacement pathway 22/2223 26/10654 6.068593877761557e-12 2.661455223515036e-11 1.1899203681885408e-11 6118/2237/328/57804/5982/54107/3978/5425/5111/5426/6119/5427/5985/142/5984/5983/6117/5981/10038/10714/5424/56655 22 Simian_virus_40 R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 56/2223 112/10654 6.097762763304809e-12 2.665536686760604e-11 1.1917451654667378e-11 6158/6138/6144/6203/9349/4736/6206/6194/6191/6128/51121/6132/6147/6129/6217/6222/6152/6136/6125/6154/51065/6141/6202/6232/6160/6155/6175/6218/6728/6209/6231/6229/6130/6142/6204/140801/6156/6143/6181/6124/6207/6233/7311/6223/3921/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/6230 56 Simian_virus_40 R-HSA-73863 RNA Polymerase I Transcription Termination 25/2223 32/10654 6.206821492464152e-12 2.7044007931450946e-11 1.2091210699605493e-11 5434/5440/902/9015/9014/25885/404672/5441/51082/5435/7270/4331/9013/7343/2966/5437/2965/64425/2068/2071/2968/84172/2967/6908/1022 25 Simian_virus_40 R-HSA-2408522 Selenoamino acid metabolism 58/2223 118/10654 6.369141336039359e-12 2.766144877982142e-11 1.2367264730173513e-11 6158/6138/6144/6203/9349/4736/6206/6194/6191/6128/51121/6132/6147/6129/6217/6222/6152/6136/2936/6125/6154/51065/6141/6202/6232/6160/6155/6175/6218/6209/6231/6229/6130/6142/6204/7965/140801/6156/6143/6181/6124/6207/6233/7311/6223/3921/6188/6189/6135/6201/9045/6187/6168/6208/6137/6122/7296/6230 58 Simian_virus_40 R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 18/2223 19/10654 8.123520700088499e-12 3.50539060434687e-11 1.5672387202743087e-11 7027/7153/286826/5934/1869/1875/993/5933/5111/4609/5928/91750/990/1874/3065/55957/7029/132660 18 Simian_virus_40 R-HSA-6804760 Regulation of TP53 Activity through Methylation 18/2223 19/10654 8.123520700088499e-12 3.50539060434687e-11 1.5672387202743087e-11 133383/11200/472/79813/7316/4194/56950/2033/7157/91875/6233/7311/10419/133746/26013/10919/7314/4193 18 Simian_virus_40 R-HSA-110312 Translesion synthesis by REV1 16/2223 16/10654 1.2365849166065263e-11 5.301907214332135e-11 2.3704503193735326e-11 6118/5982/7316/5111/10459/6119/51455/5985/5984/6233/7311/5983/6117/5981/5980/7314 16 Simian_virus_40 R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 16/2223 16/10654 1.2365849166065263e-11 5.301907214332135e-11 2.3704503193735326e-11 4605/7027/286826/5934/1869/1875/890/983/5933/5928/91750/1874/3065/55957/7029/132660 16 Simian_virus_40 R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 33/2223 51/10654 1.449806949894787e-11 6.196308683945236e-11 2.770331751391313e-11 6203/6206/6194/6191/8666/6217/6222/8668/8667/51065/8662/10480/6202/6232/6218/6209/6231/6229/6204/8894/6207/6233/6223/3646/51386/3921/6188/6189/8665/6201/6187/6208/6230 33 Simian_virus_40 R-HSA-8953750 Transcriptional Regulation by E2F6 26/2223 35/10654 1.725399760012374e-11 7.350750723608273e-11 3.286475733356903e-11 23468/5888/83746/7027/2146/6045/80012/5931/79813/11335/1869/1876/1911/5928/23512/1111/672/5932/7029/8726/648/317/23429/10919/6015/6241 26 Simian_virus_40 R-HSA-195721 Signaling by WNT 121/2223 331/10654 1.8157328793730214e-11 7.711118747210744e-11 3.447594074758901e-11 57154/5718/27123/9070/5689/27161/8945/5684/8295/857/5720/7015/6885/1487/5579/6597/5682/1499/5525/51701/864/1459/4772/5700/122706/5707/1856/5526/207/1454/1452/5690/1212/5578/57690/5717/5929/9491/23198/6500/27327/1460/143471/5706/5705/10197/6657/192670/7534/2775/8452/5530/5528/7316/10213/5709/9978/5695/1457/5714/4609/9861/5715/5519/5711/2932/5701/10524/5688/1387/440193/5687/1455/5685/5683/5698/5708/5692/5686/5713/2033/54894/5534/5699/2783/8312/5529/5710/5702/192669/3065/5719/23112/208/57680/5704/6233/5527/5716/7514/23072/7311/5518/1213/1211/331/4343/3845/6659/5694/26523/9736/5693/5721/5696/6259/5691/7314/4221/5515/5516 121 Simian_virus_40 R-HSA-68962 Activation of the pre-replicative complex 25/2223 33/10654 2.0522849401734867e-11 8.688222049567254e-11 3.8844509908646436e-11 1017/4172/6118/8318/54107/4173/5557/5422/4174/84515/5426/4171/51053/4998/6119/5427/990/4175/81620/55388/23649/6117/5558/4176/56655 25 Simian_virus_40 R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 36/2223 59/10654 2.134947913054229e-11 9.009748739996149e-11 4.028203609536281e-11 6203/6206/6194/6191/8666/6217/6222/8668/8667/51065/8662/10480/26986/6202/6232/6218/6209/6231/6229/6204/8894/6207/6233/6223/3646/51386/3921/6188/6189/8665/6201/1978/6187/6208/1974/6230 36 Simian_virus_40 R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 31/2223 47/10654 2.8809680191648288e-11 1.2119934425452039e-10 5.4187486253883933e-11 8841/79885/2648/9734/892/23462/51564/3280/6500/3091/10013/7316/9978/9611/9612/1024/4609/10014/22938/8850/1387/2033/55294/3066/3065/9794/6233/7311/3516/4851/7314 31 Simian_virus_40 R-HSA-168638 NOD1/2 Signaling Pathway 26/2223 36/10654 4.978048002167928e-11 2.0876688809091747e-10 9.333840004064866e-11 1147/834/6885/842/330/841/8517/7316/64127/7128/1432/329/3656/5603/10454/83737/3654/7189/6233/7311/5600/7334/1540/3551/6300/7314 26 Simian_virus_40 R-HSA-5358508 Mismatch Repair 15/2223 15/10654 5.958345528884432e-11 2.4832607763238846e-10 1.1102507196679065e-10 6118/4436/9156/57804/2956/4292/3978/5425/5111/5395/6119/6117/10714/5424/4437 15 Simian_virus_40 R-HSA-69183 Processive synthesis on the lagging strand 15/2223 15/10654 5.958345528884432e-11 2.4832607763238846e-10 1.1102507196679065e-10 6118/2237/1763/57804/3978/5557/5422/5425/5111/6119/23649/6117/10714/5558/5424 15 Simian_virus_40 R-HSA-72649 Translation initiation complex formation 35/2223 58/10654 6.34193547007159e-11 2.634946563726339e-10 1.1780685083724317e-10 6203/6206/6194/6191/8666/6217/6222/8668/8667/51065/8662/10480/26986/6202/6232/6218/6209/6231/6229/6204/8894/6207/6233/6223/3646/51386/3921/6188/6189/8665/6201/6187/6208/1974/6230 35 Simian_virus_40 R-HSA-3232118 SUMOylation of transcription factors 18/2223 20/10654 6.52897559654306e-11 2.704285571160737e-10 1.2090695549153815e-10 7020/6670/7021/1029/9112/51588/3090/6613/7341/10401/7022/7157/7329/7158/6612/9063/4193/8554 18 Simian_virus_40 R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 28/2223 41/10654 7.537046031189915e-11 3.112220238109805e-10 1.3914546519119842e-10 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/9972/8021/6396/129401/55746/8480/55339 28 Simian_virus_40 R-HSA-203927 MicroRNA (miRNA) biogenesis 20/2223 24/10654 1.0091235479888554e-10 4.154122090187251e-10 1.85728260366047e-10 27161/5434/5440/5430/5436/5441/192670/5438/5431/5435/54487/5433/5437/5439/192669/5901/29102/26523/5432/23405 20 Simian_virus_40 R-HSA-73886 Chromosome Maintenance 53/2223 110/10654 1.3392951635327499e-10 5.496434585507494e-10 2.4574223184087156e-10 8467/7014/6118/55839/25913/79682/2237/7015/1763/1058/401541/79019/57804/80152/4869/5982/79172/5931/54107/7013/23421/55355/64105/3978/5557/5422/10856/5425/26277/5111/5426/55166/6119/5928/2491/5427/5985/65057/1060/91687/5984/387103/51773/23649/11339/5983/6117/5981/10714/64946/5558/5424/56655 53 Simian_virus_40 R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 28/2223 42/10654 1.8115344887299974e-10 7.411827084986759e-10 3.313782601335361e-10 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/10189/10482/8086/9972/8021/6396/129401/55746/8480/55339 28 Simian_virus_40 R-HSA-9020591 Interleukin-12 signaling 30/2223 47/10654 2.044921519747426e-10 8.341290819152115e-10 3.7293401575940905e-10 5055/3592/6627/9049/27250/3593/6775/9446/3595/5908/3313/6175/3185/6950/3717/3458/3181/998/6648/5478/3716/3594/2939/302/4282/7297/5721/3586/5034/829 30 Simian_virus_40 R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 156/2223 473/10654 2.2182049177191016e-10 9.020699998724346e-10 4.0330998503983667e-10 54106/627/2963/5434/5440/1282/5590/3918/4893/857/5290/85440/5335/558/5241/5579/6678/1499/2904/5340/5747/3815/5430/10653/10048/10273/207/5436/3911/7422/1284/5578/5594/3315/284217/5908/3178/9982/51741/4318/2064/5921/5441/1277/6778/3912/5438/348/5431/6696/6776/5528/5435/3688/7316/1950/9611/3185/6774/4233/5433/3915/10413/6772/6714/2099/8651/3910/2962/5519/3673/8503/5598/1432/4208/5437/5159/4670/2567/4067/3908/3717/2247/4914/10000/3320/2335/4846/6195/3909/8471/5771/5439/1111/2264/5603/3630/998/2066/83737/3481/3913/3925/6285/208/6233/2885/1398/5867/3187/5580/2475/2246/1385/9844/6196/7311/5154/3479/5518/5155/1213/3791/2252/1956/1211/60/8851/581/6197/3845/5600/2549/6777/3265/1399/6300/1020/7057/5432/3480/5663/10319/10254/10252/51231/56034/7529/5156/7314/5595/5515/25920/6387/5516/5607 156 Simian_virus_40 R-HSA-194315 Signaling by Rho GTPases 151/2223 455/10654 2.6456332180443166e-10 1.0726404165001427e-9 4.795709760805408e-10 220134/5905/55839/11130/25/79682/5590/5903/10403/54908/6249/55143/5579/4638/1499/55055/25936/5525/9735/7531/5747/80776/1783/1058/4659/991/1856/401541/79019/5526/29/4627/51807/2316/7532/10971/348235/80152/4771/5578/9212/5594/1063/613/29127/8379/1027/3619/1894/79172/1080/7533/2810/147841/7277/348995/23421/55920/79023/57122/79980/64105/1124/6232/7534/332/1780/23122/5528/3688/5048/1781/9828/5501/9824/57405/10398/8655/4085/10552/81624/6279/6714/23279/55166/79902/3796/54821/5519/9183/7456/1432/81565/2491/1062/699/7846/999/51466/22919/1060/91687/995/79003/5529/51143/998/23028/83540/2/11004/5527/2885/5580/701/9055/7514/9184/9928/367/8826/10499/5518/10383/54820/5347/57551/60/5300/84790/84643/6396/5600/23332/25909/64946/9793/10726/10109/81930/55746/2665/140735/7280/5500/7529/4221/5595/5515/1778/5516 151 Simian_virus_40 R-HSA-174411 Polymerase switching on the C-strand of the telomere 14/2223 14/10654 2.8699319342385927e-10 1.1294570837971236e-9 5.049733608630955e-10 57804/5982/5557/5422/5425/5111/5985/5984/23649/5983/5981/10714/5558/5424 14 Simian_virus_40 R-HSA-3656237 Defective EXT2 causes exostoses 2 14/2223 14/10654 2.8699319342385927e-10 1.1294570837971236e-9 5.049733608630955e-10 2132/6385/2817/375790/3339/6383/221914/2262/2239/6382/9672/2719/10082/2131 14 Simian_virus_40 R-HSA-3656253 Defective EXT1 causes exostoses 1, TRPS2 and CHDS 14/2223 14/10654 2.8699319342385927e-10 1.1294570837971236e-9 5.049733608630955e-10 2132/6385/2817/375790/3339/6383/221914/2262/2239/6382/9672/2719/10082/2131 14 Simian_virus_40 R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 14/2223 14/10654 2.8699319342385927e-10 1.1294570837971236e-9 5.049733608630955e-10 6118/4436/9156/57804/2956/4292/3978/5425/5111/5395/6119/6117/10714/5424 14 Simian_virus_40 R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 14/2223 14/10654 2.8699319342385927e-10 1.1294570837971236e-9 5.049733608630955e-10 6118/4436/9156/57804/4292/3978/5425/5111/5395/6119/6117/10714/5424/4437 14 Simian_virus_40 R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 14/2223 14/10654 2.8699319342385927e-10 1.1294570837971236e-9 5.049733608630955e-10 1017/9134/1820/57060/25946/1027/898/1869/890/1026/7157/8900/144455/79733 14 Simian_virus_40 R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 14/2223 14/10654 2.8699319342385927e-10 1.1294570837971236e-9 5.049733608630955e-10 23368/25946/5457/207/54971/10848/5458/10000/7157/8626/208/7161/7159/51230 14 Simian_virus_40 R-HSA-69091 Polymerase switching 14/2223 14/10654 2.8699319342385927e-10 1.1294570837971236e-9 5.049733608630955e-10 57804/5982/5557/5422/5425/5111/5985/5984/23649/5983/5981/10714/5558/5424 14 Simian_virus_40 R-HSA-69109 Leading Strand Synthesis 14/2223 14/10654 2.8699319342385927e-10 1.1294570837971236e-9 5.049733608630955e-10 57804/5982/5557/5422/5425/5111/5985/5984/23649/5983/5981/10714/5558/5424 14 Simian_virus_40 R-HSA-69166 Removal of the Flap Intermediate 14/2223 14/10654 2.8699319342385927e-10 1.1294570837971236e-9 5.049733608630955e-10 6118/2237/1763/57804/5557/5422/5425/5111/6119/23649/6117/10714/5558/5424 14 Simian_virus_40 R-HSA-72702 Ribosomal scanning and start codon recognition 34/2223 58/10654 3.6039731369938866e-10 1.4141906286098818e-9 6.32275988946296e-10 6203/6206/6194/6191/8666/6217/6222/8668/8667/51065/8662/10480/6202/6232/6218/6209/6231/6229/6204/8894/6207/6233/6223/3646/51386/3921/6188/6189/8665/6201/6187/6208/1974/6230 34 Simian_virus_40 R-HSA-2559580 Oxidative Stress Induced Senescence 57/2223 125/10654 4.059621289559976e-10 1.588341624078568e-9 7.101378349084507e-10 1912/3725/1019/5601/5606/1029/7027/2146/8535/6045/57690/5594/27327/80012/5931/7295/50488/192670/8550/7316/1869/1911/1871/4194/1031/5928/1432/84733/5602/23512/1021/57332/192669/7157/23135/23112/5609/1870/6233/1032/2353/1030/7311/7029/4343/8726/5599/648/5600/23466/4217/26523/3456/7314/6015/5595/4193 57 Simian_virus_40 R-HSA-8868773 rRNA processing in the nucleus and cytosol 78/2223 195/10654 6.631914560292618e-10 2.587217831369969e-9 1.1567292837719683e-9 6158/6138/6144/2091/6203/9349/4736/6206/6194/6191/54433/6128/51121/6132/6147/25879/6129/6217/55226/27292/6222/1454/6152/6136/56902/84135/27043/6125/6154/51065/6141/6202/6232/6160/55272/6155/6175/6218/6209/10200/6231/6229/6130/6142/6204/23481/140801/6156/6143/51013/6181/6124/6207/10969/6233/25926/7311/6223/26168/11340/3921/6188/6189/26354/6135/6201/1453/9045/6187/4691/23016/6168/6208/54512/6137/10813/6122/6230 78 Simian_virus_40 R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 75/2223 185/10654 6.85766142125485e-10 2.667530906470727e-9 1.192636768913887e-9 6158/6138/6144/2091/6203/9349/4736/6206/6194/6191/6128/51121/6132/6147/25879/6129/6217/6222/1454/6152/6136/56902/84135/27043/6125/6154/51065/6141/6202/6232/6160/55272/6155/6175/6218/6209/10200/6231/6229/6130/6142/6204/23481/140801/6156/6143/51013/6181/6124/6207/10969/6233/25926/7311/6223/26168/11340/3921/6188/6189/26354/6135/6201/1453/9045/6187/4691/23016/6168/6208/54512/6137/10813/6122/6230 75 Simian_virus_40 R-HSA-212165 Epigenetic regulation of gene expression 64/2223 149/10654 7.547468927929892e-10 2.9249034628785242e-9 1.307706466264616e-9 8467/23451/5252/5434/5440/902/9015/10514/2648/2074/2146/29128/1788/9112/9219/1786/6839/9014/25885/404672/5931/5441/51082/11335/5435/200424/9031/7270/6996/4331/9013/23309/4641/7343/1108/2966/8850/5928/2932/29947/5437/57459/2965/54815/2033/23512/64425/2068/3066/3065/2071/1107/2968/57504/84172/2967/6908/23411/60/25942/8726/53615/1022/10919 64 Simian_virus_40 R-HSA-9006936 Signaling by TGF-beta family members 49/2223 102/10654 7.562902396563695e-10 2.9249034628785242e-9 1.307706466264616e-9 57154/5590/892/7027/9765/7321/6497/10273/4738/4086/130399/8239/7316/1875/9611/5501/9612/1024/6667/5933/4092/4609/4089/22938/8812/4088/1874/142/905/3065/2280/6498/9958/9040/4087/5499/6233/7514/1025/1030/7311/25937/7029/7040/904/5500/7314/4221/5054 49 Simian_virus_40 R-HSA-156711 Polo-like kinase mediated events 15/2223 16/10654 7.678475471305278e-10 2.9610672650838167e-9 1.3238750812595307e-9 4605/2305/1063/9133/286826/891/993/5928/91750/2033/995/55957/5347/7465/132660 15 Simian_virus_40 R-HSA-5654738 Signaling by FGFR2 39/2223 73/10654 8.169693449576396e-10 3.1414695155677713e-9 1.404531825142074e-9 2963/5434/5440/4893/5290/5335/5430/5436/5594/3178/9982/5441/5438/5431/5435/7316/3185/5433/6714/2962/5437/4670/2247/5439/6233/2885/3187/2246/7311/5518/2252/3845/2549/3265/5432/7314/5595/5515/5516 39 Simian_virus_40 R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 44/2223 88/10654 1.1188390553451852e-9 4.289948606494967e-9 1.9180098091631747e-9 115106/8945/22995/22981/7531/4659/203068/7532/1454/6500/7277/9133/5048/1781/7316/891/8655/983/6790/23291/7846/7283/3320/22919/10540/10733/1069/4751/6233/7311/54930/5518/10383/55835/54820/5347/9662/23332/1453/9793/8481/5500/7314/1778 44 Simian_virus_40 R-HSA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 13/2223 13/10654 1.3818527471598532e-9 5.26831359854694e-9 2.3554308190224776e-9 7027/5925/5557/5422/1869/5519/28227/7029/5518/23649/5558/5515/5516 13 Simian_virus_40 R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13/2223 13/10654 1.3818527471598532e-9 5.26831359854694e-9 2.3554308190224776e-9 7531/7532/10971/7533/2810/11200/7534/891/983/995/1111/7465/7529 13 Simian_virus_40 R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 22/2223 31/10654 2.723110735765033e-9 1.0352449312738454e-8 4.628516831328668e-9 3725/5601/5594/5528/5519/5598/1432/4208/5602/6195/1385/2353/6196/5518/1386/6197/5599/5600/51231/5595/5515/5516 22 Simian_virus_40 R-HSA-975634 Retinoid metabolism and transport 27/2223 43/10654 2.8357491807183848e-9 1.0750212995830712e-8 4.806354543590483e-9 5947/7276/6385/344/2817/345/375790/3339/8644/6383/26020/348/338/335/336/1109/221914/4035/2262/2239/7804/6382/4036/29967/9672/2719/10082 27 Simian_virus_40 R-HSA-400253 Circadian Clock 37/2223 70/10654 3.279269261352655e-9 1.2396561545733135e-8 5.542426920596037e-9 8945/8841/1454/6500/3091/200186/4783/6720/5465/7316/9611/5469/5501/8553/4208/1387/150094/2908/6604/2033/79365/5499/10498/6233/1385/7311/10499/23054/8864/1386/23411/1453/8648/5500/10891/7314/5054 37 Simian_virus_40 R-HSA-156590 Glutathione conjugation 24/2223 36/10654 3.7109469791738865e-9 1.3989019230481337e-8 6.254405021079584e-9 4258/2954/653689/2948/9446/4257/2947/2938/2946/2949/2940/2687/4259/2686/221357/27306/2678/2944/2939/373156/2937/119391/2941/2950 24 Simian_virus_40 R-HSA-72312 rRNA processing 79/2223 205/10654 3.982164791721052e-9 1.4969370169438802e-8 6.692713935665635e-9 6158/6138/6144/2091/6203/9349/4736/6206/6194/6191/54433/6128/51121/6132/6147/25879/6129/6217/55226/27292/6222/1454/6152/6136/56902/84135/27043/6125/6154/51065/6141/6202/6232/6160/55272/6155/6175/6218/54931/6209/10200/6231/6229/6130/6142/6204/23481/140801/6156/6143/51013/6181/6124/6207/10969/6233/25926/7311/6223/26168/11340/3921/6188/6189/26354/6135/6201/1453/9045/6187/4691/23016/6168/6208/54512/6137/10813/6122/6230 79 Simian_virus_40 R-HSA-8934593 Regulation of RUNX1 Expression and Activity 15/2223 17/10654 5.257914322257765e-9 1.965493320465159e-8 8.787600538592365e-9 27161/894/57690/27327/192670/865/6714/1021/595/192669/896/5371/23112/4343/26523 15 Simian_virus_40 R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 15/2223 17/10654 5.257914322257765e-9 1.965493320465159e-8 8.787600538592365e-9 2308/857/2290/2309/57060/4303/1027/5934/1026/901/4089/1647/9314/4088/4087 15 Simian_virus_40 R-HSA-110320 Translesion Synthesis by POLH 16/2223 19/10654 6.248203882369785e-9 2.3227395041939755e-8 1.0384826397290501e-8 6118/5982/7316/5111/7415/6119/5429/5985/25898/5984/6233/7311/5983/6117/5981/7314 16 Simian_virus_40 R-HSA-8851708 Signaling by FGFR2 IIIa TM 16/2223 19/10654 6.248203882369785e-9 2.3227395041939755e-8 1.0384826397290501e-8 2963/5434/5440/5430/5436/5441/5438/5431/5435/5433/2962/5437/2247/5439/2246/5432 16 Simian_virus_40 R-HSA-389513 CTLA4 inhibitory signaling 17/2223 21/10654 6.426444925482073e-9 2.3824003011041276e-8 1.0651566174832165e-8 5525/5526/207/941/5528/6714/5519/4067/10000/5529/942/208/5527/5518/1493/5515/5516 17 Simian_virus_40 R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 12/2223 12/10654 6.651142892480878e-9 2.4589073723717185e-8 1.0993624615670872e-8 23368/8793/3486/355/8794/124446/8797/7157/8626/7161/7159/8795 12 Simian_virus_40 R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 31/2223 55/10654 8.070111256629696e-9 2.97529925999919e-8 1.3302381192246751e-8 3303/5241/1783/51807/10294/7277/3337/1780/1781/3305/8655/832/7846/2908/3320/51143/3301/10540/3326/3306/367/10383/84790/3304/3312/140735/7280/2288/10728/829/1778 31 Simian_virus_40 R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 39/2223 78/10654 9.826045132695011e-9 3.6127541282401936e-8 1.6152402957854814e-8 1147/3665/351/4790/7321/4214/9636/841/7706/8517/9474/7316/5970/4792/4793/3093/3146/7128/1387/843/2033/6288/54941/83737/3661/9246/7189/3439/6285/51191/6233/7311/55593/7318/5300/1540/3551/3456/7314 39 Simian_virus_40 R-HSA-191859 snRNP Assembly 30/2223 53/10654 1.2288592657566221e-8 4.493539876417948e-8 2.0090342219454315e-8 23165/5903/11218/55706/7175/6606/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/79084/8086/9972/6634/10419/8021/6396/129401/55746/8480 30 Simian_virus_40 R-HSA-194441 Metabolism of non-coding RNA 30/2223 53/10654 1.2288592657566221e-8 4.493539876417948e-8 2.0090342219454315e-8 23165/5903/11218/55706/7175/6606/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/79084/8086/9972/6634/10419/8021/6396/129401/55746/8480 30 Simian_virus_40 R-HSA-5675221 Negative regulation of MAPK pathway 25/2223 40/10654 1.2672412186929564e-8 4.621298139907466e-8 2.0661541609124288e-8 4893/1844/5525/5526/5594/5528/7316/5037/5519/5529/5894/6233/5527/7311/5518/5536/1843/3845/3265/369/7529/7314/5595/5515/5516 25 Simian_virus_40 R-HSA-3371568 Attenuation phase 13/2223 14/10654 1.5615026945727823e-8 5.66361247599101e-8 2.532166531739647e-8 3303/3337/3305/1387/3320/2033/3326/3306/3304/3312/3297/2288/10728 13 Simian_virus_40 R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 13/2223 14/10654 1.5615026945727823e-8 5.66361247599101e-8 2.532166531739647e-8 23368/79370/9540/332/64065/5876/7157/8626/604/7161/7159/10397/5875 13 Simian_virus_40 R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 22/2223 33/10654 1.6846978873970463e-8 6.09397456842813e-8 2.7245787936340375e-8 1147/351/4790/6885/8517/7316/5970/4792/4793/3146/64127/3656/10454/6288/3654/7189/6285/6233/7311/7334/3551/7314 22 Simian_virus_40 R-HSA-8940973 RUNX2 regulates osteoblast differentiation 18/2223 24/10654 1.932796681229717e-8 6.972615984436236e-8 3.117414001983414e-8 25/8841/23462/5594/3280/5925/10013/1277/632/865/4094/10413/6714/25925/25937/367/860/5595 18 Simian_virus_40 R-HSA-113510 E2F mediated regulation of DNA replication 17/2223 22/10654 2.2753285438916992e-8 8.186302696789974e-8 3.660045915107291e-8 7027/5925/5557/5422/1869/891/983/84515/5519/4998/28227/7029/5518/23649/5558/5515/5516 17 Simian_virus_40 R-HSA-5693606 DNA Double Strand Break Response 38/2223 77/10654 2.3985044932760513e-8 8.60639847587289e-8 3.847868171031098e-8 8467/25/3838/322/10111/51588/51720/11200/472/7336/580/29086/7316/2140/2070/9031/9656/7341/10524/4683/165918/7157/9682/7329/8924/6233/672/7158/7311/2138/9025/79184/23030/5536/5599/7334/2139/7314 38 Simian_virus_40 R-HSA-3560782 Diseases associated with glycosaminoglycan metabolism 25/2223 41/10654 2.604788035898662e-8 9.321668117802679e-8 4.16766085743786e-8 10675/5549/633/126792/2132/6385/2817/375790/3339/1634/6383/1462/1463/221914/2262/1464/11285/2239/6382/9672/2719/26229/10082/63827/2131 25 Simian_virus_40 R-HSA-174414 Processive synthesis on the C-strand of the telomere 11/2223 11/10654 3.2001859767031574e-8 1.1361506827342955e-7 5.079660280481202e-8 6118/2237/1763/57804/3978/5425/5111/6119/6117/10714/5424 11 Simian_virus_40 R-HSA-2514853 Condensation of Prometaphase Chromosomes 11/2223 11/10654 3.2001859767031574e-8 1.1361506827342955e-7 5.079660280481202e-8 64151/1459/1460/9133/10051/891/1457/983/23397/9918/10592 11 Simian_virus_40 R-HSA-9614399 Regulation of localization of FOXO transcription factors 11/2223 11/10654 3.2001859767031574e-8 1.1361506827342955e-7 5.079660280481202e-8 2308/2309/7532/207/10971/4303/2810/7534/10000/208/7529 11 Simian_virus_40 R-HSA-6806667 Metabolism of fat-soluble vitamins 27/2223 47/10654 4.312534280255448e-8 1.5270240116366255e-7 6.827231050536329e-8 5947/7276/6385/344/2817/345/375790/3339/8644/6383/26020/348/338/335/336/1109/221914/4035/2262/2239/7804/6382/4036/29967/9672/2719/10082 27 Simian_virus_40 R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 31/2223 58/10654 4.3771683365650794e-8 1.5297291426224834e-7 6.839325525882936e-8 8841/79885/2648/9734/892/23462/51564/3280/6500/10013/7316/9978/9611/9612/1024/4609/10014/22938/8850/1387/2033/55294/3066/3065/9794/6233/7311/3516/4851/5663/7314 31 Simian_virus_40 R-HSA-2644603 Signaling by NOTCH1 in Cancer 31/2223 58/10654 4.3771683365650794e-8 1.5297291426224834e-7 6.839325525882936e-8 8841/79885/2648/9734/892/23462/51564/3280/6500/10013/7316/9978/9611/9612/1024/4609/10014/22938/8850/1387/2033/55294/3066/3065/9794/6233/7311/3516/4851/5663/7314 31 Simian_virus_40 R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 31/2223 58/10654 4.3771683365650794e-8 1.5297291426224834e-7 6.839325525882936e-8 8841/79885/2648/9734/892/23462/51564/3280/6500/10013/7316/9978/9611/9612/1024/4609/10014/22938/8850/1387/2033/55294/3066/3065/9794/6233/7311/3516/4851/5663/7314 31 Simian_virus_40 R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 31/2223 58/10654 4.3771683365650794e-8 1.5297291426224834e-7 6.839325525882936e-8 8841/79885/2648/9734/892/23462/51564/3280/6500/10013/7316/9978/9611/9612/1024/4609/10014/22938/8850/1387/2033/55294/3066/3065/9794/6233/7311/3516/4851/5663/7314 31 Simian_virus_40 R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 31/2223 58/10654 4.3771683365650794e-8 1.5297291426224834e-7 6.839325525882936e-8 8841/79885/2648/9734/892/23462/51564/3280/6500/10013/7316/9978/9611/9612/1024/4609/10014/22938/8850/1387/2033/55294/3066/3065/9794/6233/7311/3516/4851/5663/7314 31 Simian_virus_40 R-HSA-8854691 Interleukin-20 family signaling 18/2223 25/10654 5.5522269917980985e-8 1.9353476942839086e-7 8.652821285919115e-8 6775/50616/11009/53833/6776/6774/6772/3717/29949/116379/163702/58985/3716/53832/3588/6777/6773/7297 18 Simian_virus_40 R-HSA-5693565 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 37/2223 76/10654 5.7794470638498404e-8 2.009331077638986e-7 8.983596472305451e-8 8467/25/322/10111/51588/51720/11200/472/7336/580/29086/7316/2140/2070/9031/9656/7341/10524/4683/165918/7157/9682/7329/8924/6233/672/7158/7311/2138/9025/79184/23030/5536/5599/7334/2139/7314 37 Simian_virus_40 R-HSA-209560 NF-kB is activated and signals survival 12/2223 13/10654 6.9882624636333e-8 2.423319955089377e-7 1.0834515447493489e-7 4804/4790/8878/7316/5970/4792/3654/7189/6233/7311/3551/7314 12 Simian_virus_40 R-HSA-70171 Glycolysis 35/2223 71/10654 8.842301298923877e-8 3.058342356483465e-7 1.3673661802459604e-7 23165/5903/2597/55706/7175/9631/5315/348995/79023/57122/23636/10762/23511/5528/53371/5230/23279/4927/9688/79902/5519/9883/23225/2821/8086/9972/5518/8021/6396/129401/230/55746/8480/5515/5516 35 Simian_virus_40 R-HSA-6807505 RNA polymerase II transcribes snRNA genes 36/2223 74/10654 8.923415793855461e-8 3.0784637520190303e-7 1.3763623332424877e-7 6884/2963/5434/5440/55197/5430/5436/6878/6617/5441/5438/5431/5435/5433/6667/58490/2962/5437/8812/905/64859/5439/6827/1025/6880/6908/80237/6619/79035/904/6829/6882/1022/5432/8178/6877 36 Simian_virus_40 R-HSA-111447 Activation of BAD and translocation to mitochondria 13/2223 15/10654 9.455296016541751e-8 3.2042947611613713e-7 1.4326206085669318e-7 596/7531/7532/207/10971/7533/2810/7534/10000/5534/208/637/7529 13 Simian_virus_40 R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 13/2223 15/10654 9.455296016541751e-8 3.2042947611613713e-7 1.4326206085669318e-7 1499/5525/5526/1452/5528/5519/2932/8312/5529/5527/5518/5515/5516 13 Simian_virus_40 R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 13/2223 15/10654 9.455296016541751e-8 3.2042947611613713e-7 1.4326206085669318e-7 1499/5525/5526/1452/5528/5519/2932/8312/5529/5527/5518/5515/5516 13 Simian_virus_40 R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 13/2223 15/10654 9.455296016541751e-8 3.2042947611613713e-7 1.4326206085669318e-7 1499/5525/5526/1452/5528/5519/2932/8312/5529/5527/5518/5515/5516 13 Simian_virus_40 R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 13/2223 15/10654 9.455296016541751e-8 3.2042947611613713e-7 1.4326206085669318e-7 1499/5525/5526/1452/5528/5519/2932/8312/5529/5527/5518/5515/5516 13 Simian_virus_40 R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 13/2223 15/10654 9.455296016541751e-8 3.2042947611613713e-7 1.4326206085669318e-7 1499/5525/5526/1452/5528/5519/2932/8312/5529/5527/5518/5515/5516 13 Simian_virus_40 R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 13/2223 15/10654 9.455296016541751e-8 3.2042947611613713e-7 1.4326206085669318e-7 1499/5525/5526/1452/5528/5519/2932/8312/5529/5527/5518/5515/5516 13 Simian_virus_40 R-HSA-350054 Notch-HLH transcription pathway 19/2223 28/10654 1.0642318631265284e-7 3.597478993238794e-7 1.6084108762617562e-7 8841/79885/2648/9734/51564/10013/4854/9611/9612/10014/22938/8850/1387/4855/3066/3065/9794/3516/4851 19 Simian_virus_40 R-HSA-190236 Signaling by FGFR 40/2223 87/10654 1.2424067544924525e-7 4.189220765147918e-7 1.8729750067725414e-7 2963/5434/5440/4893/5290/5335/5430/5436/5594/3178/9982/5441/5438/5431/5435/7316/3185/5433/6714/2962/5437/4670/2247/5439/2264/6233/2885/3187/2246/7311/5518/2252/3845/2549/3265/5432/7314/5595/5515/5516 40 Simian_virus_40 R-HSA-1226099 Signaling by FGFR in disease 32/2223 63/10654 1.2909644979110743e-7 4.3420409929740894e-7 1.9412999968587583e-7 2963/8805/5434/5440/4893/5290/5335/5430/5436/613/5441/5438/5431/6776/5435/6774/5433/6772/2962/5437/2247/5439/2264/2885/2246/2252/3845/2549/6777/3265/5432/1523 32 Simian_virus_40 R-HSA-6803529 FGFR2 alternative splicing 18/2223 26/10654 1.4516523061580095e-7 4.870293487160122e-7 2.1774784592370144e-7 2963/5434/5440/5430/5436/3178/5441/5438/5431/5435/3185/5433/2962/5437/4670/5439/3187/5432 18 Simian_virus_40 R-HSA-174437 Removal of the Flap Intermediate from the C-strand 10/2223 10/10654 1.539212812292287e-7 5.100305170608022e-7 2.2803152774700547e-7 6118/2237/1763/57804/5425/5111/6119/6117/10714/5424 10 Simian_virus_40 R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 10/2223 10/10654 1.539212812292287e-7 5.100305170608022e-7 2.2803152774700547e-7 5563/51422/53632/1432/5571/5600/5564/6300/5565/10891 10 Simian_virus_40 R-HSA-390450 Folding of actin by CCT/TriC 10/2223 10/10654 1.539212812292287e-7 5.100305170608022e-7 2.2803152774700547e-7 10694/10575/7203/10576/908/6950/10574/60/22948/10693 10 Simian_virus_40 R-HSA-450341 Activation of the AP-1 family of transcription factors 10/2223 10/10654 1.539212812292287e-7 5.100305170608022e-7 2.2803152774700547e-7 3725/5601/5594/1432/5602/2353/1386/5599/5600/5595 10 Simian_virus_40 R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 10/2223 10/10654 1.539212812292287e-7 5.100305170608022e-7 2.2803152774700547e-7 2308/2309/4303/23410/7295/8850/1387/10628/2033/23411 10 Simian_virus_40 R-HSA-451927 Interleukin-2 family signaling 25/2223 44/10654 1.8385371891144624e-7 6.07713524086603e-7 2.717050033174082e-7 3562/5290/1437/3561/3578/6775/3568/1438/3581/6776/3560/50615/6774/6772/8503/3567/3558/3717/3563/2885/3716/6777/3600/3559/59067 25 Simian_virus_40 R-HSA-71387 Metabolism of carbohydrates 99/2223 295/10654 1.8679485756695762e-7 6.15918179004563e-7 2.753732543984633e-7 23165/9951/5903/10675/5549/2597/633/8509/55706/7175/126792/2132/6385/960/9631/2817/375790/5315/2998/64132/3161/3339/1634/5634/348995/79023/9957/57122/23636/5257/6383/55276/10762/9653/3340/23511/222537/5528/7316/53371/5230/2539/9956/266722/64579/1462/27087/23279/4927/9688/9394/9953/79902/9955/5519/9883/135152/5256/23225/2821/4190/1463/26035/221914/2262/9348/8086/5261/2584/2582/64131/1464/6233/11285/2239/7311/60495/9972/10855/64711/5518/6382/8021/90161/6396/129401/9672/2719/230/55746/26229/10082/8480/63827/6513/7314/5515/2131/5516 99 Simian_virus_40 R-HSA-3371571 HSF1-dependent transactivation 17/2223 24/10654 1.9373659873134408e-7 6.372414595526072e-7 2.8490676284021193e-7 3303/1410/3337/3305/26353/1387/3320/2033/3326/2475/3306/3304/3312/3297/57521/2288/10728 17 Simian_virus_40 R-HSA-6806834 Signaling by MET 37/2223 79/10654 2.0431030375560582e-7 6.703775736919878e-7 2.9972171700088877e-7 3918/4893/5290/85440/5747/10653/10048/3911/284217/5908/1277/3912/3688/7316/6774/4233/3915/6714/3910/3673/3908/2335/3909/5771/3913/6233/2885/1398/5867/7311/3845/2549/3265/1399/10319/10254/7314 37 Simian_virus_40 R-HSA-8854518 AURKA Activation by TPX2 35/2223 73/10654 2.1199852297240042e-7 6.939073605584423e-7 3.102417409352201e-7 115106/22995/22981/7531/203068/7532/1454/22974/3161/7277/5048/1781/8655/983/6790/7846/7283/3320/22919/10540/10733/1069/4751/54930/5518/10383/55835/54820/5347/9662/23332/1453/9793/8481/1778 35 Simian_virus_40 R-HSA-186763 Downstream signal transduction 19/2223 29/10654 2.481835812448636e-7 8.103707202691165e-7 3.623117974377571e-7 4893/5290/5335/5921/6778/6776/6774/6772/6714/5159/2885/1398/5154/5155/3845/6777/3265/1399/5156 19 Simian_virus_40 R-HSA-68875 Mitotic Prophase 56/2223 142/10654 2.954639408464282e-7 9.624092442133657e-7 4.3028729249479837e-7 4000/23165/5903/55706/7175/5579/9631/91754/2801/5578/5594/5861/5925/348995/79023/9133/57122/23636/23310/7443/10762/10051/23511/891/53371/26003/983/23279/4927/9688/79902/8615/5519/81876/9883/23225/7444/8086/2010/79648/9972/5518/5347/54892/8021/6396/129401/6418/55746/7112/10592/29781/8480/5595/5515/5516 56 Simian_virus_40 R-HSA-3000171 Non-integrin membrane-ECM interactions 30/2223 59/10654 3.0877081119670086e-7 1.0033182291185776e-6 4.485774496804371e-7 7276/1282/3918/6385/375790/3911/1284/5578/3339/284217/1277/6383/3912/3688/3915/3910/3673/3908/2247/1605/2335/3909/3913/5154/5155/6382/7040/9672/7057/10319 30 Simian_virus_40 R-HSA-3371511 HSF1 activation 11/2223 12/10654 3.108597453870892e-7 1.0076661311823037e-6 4.5052137012621625e-7 6118/7531/1915/10013/7415/6119/3320/3326/6117/3297/10728 11 Simian_virus_40 R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 49/2223 119/10654 3.5026021805595707e-7 1.1326487051351671e-6 5.064003152616247e-7 8841/5468/29079/892/9440/4802/6721/1543/90390/6720/6837/5465/335/9611/5469/2874/4800/9612/1024/6667/23309/336/1387/10001/6604/9439/2033/9967/84246/4801/51003/10498/183/2274/9477/112950/55588/10499/23054/25942/196/9412/405/8202/9282/8648/54797/10891/7296 49 Simian_virus_40 R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 14/2223 18/10654 3.7158152608682625e-7 1.1984370628780162e-6 5.358138880229581e-7 4893/5578/5594/4314/5598/6195/2885/1385/6196/1956/6197/3845/3265/5595 14 Simian_virus_40 R-HSA-8941326 RUNX2 regulates bone development 20/2223 32/10654 3.7239065217595585e-7 1.1984370628780162e-6 5.358138880229581e-7 25/8841/23462/5594/3280/4086/5925/10013/1277/632/865/4094/10413/6714/4089/25925/25937/367/860/5595 20 Simian_virus_40 R-HSA-71291 Metabolism of amino acids and derivatives 118/2223 372/10654 3.952704620366982e-7 1.2517574973271465e-6 5.596531284622115e-7 6158/5718/5689/6138/6144/6203/5684/27165/9349/4736/1728/5720/6206/6194/6191/6128/55256/5682/51121/6132/6147/6129/3620/5160/6217/5700/122706/5707/2954/6222/1743/383/6152/5690/6136/2936/6125/5717/9491/23198/6154/51065/6141/143471/6202/5706/4552/5705/10197/6232/6160/6155/10213/5709/6175/6218/5695/23498/6209/5714/6231/6229/9861/6130/5715/6142/5711/6204/5701/5688/58478/5687/23474/5685/5683/5698/5708/7965/5692/5686/5713/5831/140801/6156/5699/6143/5710/6181/6124/5702/6207/5719/5704/6233/5716/7311/6223/3921/6188/6189/29968/6135/6201/6303/5694/9045/6187/435/6168/5693/6208/5721/6137/5696/5691/6122/7296/6230 118 Simian_virus_40 R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 12/2223 14/10654 3.9548821077996284e-7 1.2517574973271465e-6 5.596531284622115e-7 5525/5526/1452/5528/5519/2932/8312/5529/5527/5518/5515/5516 12 Simian_virus_40 R-HSA-4839744 truncated APC mutants destabilize the destruction complex 12/2223 14/10654 3.9548821077996284e-7 1.2517574973271465e-6 5.596531284622115e-7 5525/5526/1452/5528/5519/2932/8312/5529/5527/5518/5515/5516 12 Simian_virus_40 R-HSA-4839748 AMER1 mutants destabilize the destruction complex 12/2223 14/10654 3.9548821077996284e-7 1.2517574973271465e-6 5.596531284622115e-7 5525/5526/1452/5528/5519/2932/8312/5529/5527/5518/5515/5516 12 Simian_virus_40 R-HSA-5467337 APC truncation mutants have impaired AXIN binding 12/2223 14/10654 3.9548821077996284e-7 1.2517574973271465e-6 5.596531284622115e-7 5525/5526/1452/5528/5519/2932/8312/5529/5527/5518/5515/5516 12 Simian_virus_40 R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 12/2223 14/10654 3.9548821077996284e-7 1.2517574973271465e-6 5.596531284622115e-7 5525/5526/1452/5528/5519/2932/8312/5529/5527/5518/5515/5516 12 Simian_virus_40 R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 12/2223 14/10654 3.9548821077996284e-7 1.2517574973271465e-6 5.596531284622115e-7 5525/5526/1452/5528/5519/2932/8312/5529/5527/5518/5515/5516 12 Simian_virus_40 R-HSA-193639 p75NTR signals via NF-kB 13/2223 16/10654 4.0725520619829685e-7 1.2829494993382966e-6 5.735988819694322e-7 4804/4790/8878/4615/7316/5970/4792/3654/7189/6233/7311/3551/7314 13 Simian_virus_40 R-HSA-9614657 FOXO-mediated transcription of cell death genes 13/2223 16/10654 4.0725520619829685e-7 1.2829494993382966e-6 5.735988819694322e-7 2308/27113/2309/10018/4802/4303/4800/10370/1387/6794/2033/4801/604 13 Simian_virus_40 R-HSA-6783310 Fanconi Anemia Pathway 23/2223 40/10654 4.2585576950415717e-7 1.3384038470130653e-6 5.983921819730546e-7 6118/2176/545/80198/2072/7316/197342/6119/84464/9937/2177/29089/84126/7398/55215/57599/6233/2067/146956/7311/6117/57697/7314 23 Simian_virus_40 R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 31/2223 63/10654 5.048654530166657e-7 1.5830127054868349e-6 7.077553079672883e-7 1147/3665/5434/5440/4790/1499/7520/5441/51082/8517/6778/4615/7098/5591/5435/7316/51428/5970/4792/4793/3428/1387/5437/2033/22954/3661/6233/7311/3551/2547/7314 31 Simian_virus_40 R-HSA-5655253 Signaling by FGFR2 in disease 24/2223 43/10654 5.086607329339221e-7 1.5911951132804743e-6 7.11413612494996e-7 2963/5434/5440/4893/5290/5335/5430/5436/5441/5438/5431/5435/5433/2962/5437/2247/5439/2885/2246/2252/3845/2549/3265/5432 24 Simian_virus_40 R-HSA-3000157 Laminin interactions 19/2223 30/10654 5.443903344940632e-7 1.6950622480070367e-6 7.578519737736379e-7 1282/3918/3911/1284/3339/4811/284217/3912/3688/3672/3915/3910/3673/22795/3908/3909/3913/80781/10319 19 Simian_virus_40 R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 19/2223 30/10654 5.443903344940632e-7 1.6950622480070367e-6 7.578519737736379e-7 7124/1147/6885/7375/330/27005/8517/7316/7128/7132/329/10616/10454/6233/7311/331/1540/3551/7314 19 Simian_virus_40 R-HSA-5696394 DNA Damage Recognition in GG-NER 22/2223 38/10654 6.468110499638887e-7 2.004666117901937e-6 8.962739722363353e-7 9318/86/8450/7316/9978/1643/1642/142/10987/1069/6233/2873/7311/60/5887/10038/5886/7508/7314/51138/8451/7528 22 Simian_virus_40 R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 22/2223 38/10654 6.468110499638887e-7 2.004666117901937e-6 8.962739722363353e-7 5055/6627/9049/27250/6775/9446/5908/3313/6175/3185/6950/3458/3181/998/6648/5478/2939/302/4282/5721/3586/829 22 Simian_virus_40 R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 16/2223 23/10654 6.652800090897299e-7 2.057156157139211e-6 9.19741948050318e-7 5601/6885/8517/7316/64127/5602/3656/10454/3654/7189/5609/6233/7311/5599/7334/7314 16 Simian_virus_40 R-HSA-1980143 Signaling by NOTCH1 34/2223 73/10654 7.445440141205557e-7 2.2969610734477835e-6 1.026957260855939e-6 8841/79885/2648/9734/892/23462/51564/3280/6500/3091/10013/7316/9978/9611/8650/9612/1024/4609/10014/22938/8850/1387/2033/55294/3066/3065/83737/9794/6233/7311/3516/4851/5663/7314 34 Simian_virus_40 R-HSA-9022692 Regulation of MECP2 expression and activity 20/2223 33/10654 7.59998296918096e-7 2.3392608129910204e-6 1.0458692159423342e-6 27161/8841/2290/9212/57690/27327/192670/9611/28996/2874/9612/3064/192669/3066/3065/23112/1385/25942/4343/26523 20 Simian_virus_40 R-HSA-8875878 MET promotes cell motility 23/2223 41/10654 7.789863768156007e-7 2.3922190336076344e-6 1.0695465127902983e-6 3918/85440/5747/3911/284217/5908/1277/3912/3688/4233/3915/6714/3910/3673/3908/2335/3909/3913/2885/1398/2549/1399/10319 23 Simian_virus_40 R-HSA-9009391 Extra-nuclear estrogen signaling 35/2223 77/10654 1.055075461510284e-6 3.23267413092877e-6 1.445308851383951e-6 596/5590/4893/857/5290/2309/5747/207/5594/1027/3315/4318/2100/4313/1950/4314/6714/2099/8503/10000/3320/4846/595/2783/208/7514/1385/2353/1956/3845/3276/3265/3480/2773/5595 35 Simian_virus_40 R-HSA-1793185 Chondroitin sulfate/dermatan sulfate metabolism 26/2223 50/10654 1.0830715184748088e-6 3.3108928879116023e-6 1.4802799796922217e-6 10675/633/126792/6385/2817/375790/64132/3339/1634/6383/1462/27087/135152/1463/221914/2262/64131/1464/11285/2239/6382/9672/2719/26229/10082/63827 26 Simian_virus_40 R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 14/2223 19/10654 1.1395287635857094e-6 3.4676816343129752e-6 1.5503792701846386e-6 4893/5290/5335/7316/1950/3320/6233/2885/7311/1956/3845/2549/3265/7314 14 Simian_virus_40 R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 14/2223 19/10654 1.1395287635857094e-6 3.4676816343129752e-6 1.5503792701846386e-6 4893/5290/5335/7316/1950/3320/6233/2885/7311/1956/3845/2549/3265/7314 14 Simian_virus_40 R-HSA-8986944 Transcriptional Regulation by MECP2 30/2223 62/10654 1.2130248896138823e-6 3.6829850720855882e-6 1.6466401216478042e-6 27161/627/8841/2290/5468/2904/9212/57690/27327/6657/192670/54487/9611/28996/2874/4233/9612/4988/4208/3064/5728/192669/3066/3065/3654/23112/1385/25942/4343/26523 30 Simian_virus_40 R-HSA-199418 Negative regulation of the PI3K/AKT network 45/2223 110/10654 1.2944234957773842e-6 3.921255826937358e-6 1.7531695202402494e-6 5290/90865/5525/3815/5526/207/5594/930/941/2064/4615/5528/2100/1950/4233/6714/2099/5519/8503/5159/2247/10000/5728/5529/2264/3630/2066/942/3654/7189/208/5527/2885/2246/5154/5518/5155/2252/1956/2549/5156/940/5595/5515/5516 45 Simian_virus_40 R-HSA-196299 Beta-catenin phosphorylation cascade 13/2223 17/10654 1.398213856156977e-6 4.2166359437363215e-006 1.8852321656049133e-6 1499/5525/5526/1452/5528/5519/2932/8312/5529/5527/5518/5515/5516 13 Simian_virus_40 R-HSA-4655427 SUMOylation of DNA methylation proteins 13/2223 17/10654 1.398213856156977e-6 4.2166359437363215e-006 1.8852321656049133e-6 1912/1788/8535/1786/6045/80012/1911/7341/84733/57332/7329/648/6015 13 Simian_virus_40 R-HSA-1989781 PPARA activates gene expression 47/2223 117/10654 1.4082788250111525e-6 4.237466778396787e-6 1.8945455044993087e-6 8841/5468/29079/892/9440/4802/6721/1543/90390/6720/6837/5465/335/9611/5469/2874/4800/9612/1024/6667/336/1387/10001/6604/9439/2033/9967/84246/4801/51003/10498/183/2274/9477/112950/55588/10499/23054/196/9412/405/8202/9282/8648/54797/10891/7296 47 Simian_virus_40 R-HSA-1630316 Glycosaminoglycan metabolism 49/2223 124/10654 1.4970049358431718e-6 4.494363811860261e-6 2.00940259844721e-6 9951/10675/5549/633/8509/126792/2132/6385/960/2817/375790/64132/3161/3339/1634/9957/6383/9653/3340/222537/9956/266722/64579/1462/27087/9394/9953/9955/135152/1463/26035/221914/2262/9348/64131/1464/11285/2239/60495/10855/64711/6382/90161/9672/2719/26229/10082/63827/2131 49 Simian_virus_40 R-HSA-937039 IRAK1 recruits IKK complex 12/2223 15/10654 1.599229213238142e-6 4.769256898145748e-6 2.132305617650856e-6 1147/8517/7316/57162/3654/7189/6233/7311/7334/3551/57161/7314 12 Simian_virus_40 R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 12/2223 15/10654 1.599229213238142e-6 4.769256898145748e-6 2.132305617650856e-6 54106/3665/4615/7316/3654/7189/6233/51311/7311/7334/51284/7314 12 Simian_virus_40 R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 12/2223 15/10654 1.599229213238142e-6 4.769256898145748e-6 2.132305617650856e-6 1147/8517/7316/57162/3654/7189/6233/7311/7334/3551/57161/7314 12 Simian_virus_40 R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 25/2223 48/10654 1.6763293323876216e-6 4.988101915885118e-6 2.230149887877102e-6 3562/5290/1437/3561/3568/1438/7534/6776/7316/3560/8503/3567/4067/3558/3717/3563/6233/2885/1398/3716/7311/6777/1399/3559/7314 25 Simian_virus_40 R-HSA-2219528 PI3K/AKT Signaling in Cancer 42/2223 101/10654 1.7387084971871384e-6 5.162271688551194e-6 2.308020129009476e-6 1147/2308/5290/2309/842/3815/207/4303/1027/7249/930/941/2064/2100/1950/4233/1026/6714/2099/8503/2932/5159/2247/3164/10000/5728/2264/2066/942/208/2885/2475/2246/1385/5154/5155/2252/1956/2549/5156/940/4193 42 Simian_virus_40 R-HSA-2173789 TGF-beta receptor signaling activates SMADs 19/2223 32/10654 2.2404343919449983e-6 6.6060190189378485e-6 2.95351073872035e-6 57154/10273/4738/7316/5501/4092/4089/4088/2280/9958/9040/4087/5499/6233/7514/7311/7040/5500/7314 19 Simian_virus_40 R-HSA-198753 ERK/MAPK targets 15/2223 22/10654 2.2446681614274657e-6 6.6060190189378485e-6 2.95351073872035e-6 5594/5528/5519/5598/1432/4208/6195/6196/5518/6197/5600/51231/5595/5515/5516 15 Simian_virus_40 R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 15/2223 22/10654 2.2446681614274657e-6 6.6060190189378485e-6 2.95351073872035e-6 4000/3725/351/994/2309/10018/7531/823/2801/993/995/6648/8851/5052/1020 15 Simian_virus_40 R-HSA-8863678 Neurodegenerative Diseases 15/2223 22/10654 2.2446681614274657e-6 6.6060190189378485e-6 2.95351073872035e-6 4000/3725/351/994/2309/10018/7531/823/2801/993/995/6648/8851/5052/1020 15 Simian_virus_40 R-HSA-380259 Loss of Nlp from mitotic centrosomes 32/2223 70/10654 2.6031336819272637e-6 7.62752270992661e-6 3.410218797284625e-6 115106/22995/22981/7531/203068/7532/1454/7277/5048/1781/8655/983/7846/7283/3320/22919/10540/10733/1069/4751/54930/5518/10383/55835/54820/5347/9662/23332/1453/9793/8481/1778 32 Simian_virus_40 R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 32/2223 70/10654 2.6031336819272637e-6 7.62752270992661e-6 3.410218797284625e-6 115106/22995/22981/7531/203068/7532/1454/7277/5048/1781/8655/983/7846/7283/3320/22919/10540/10733/1069/4751/54930/5518/10383/55835/54820/5347/9662/23332/1453/9793/8481/1778 32 Simian_virus_40 R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 42/2223 103/10654 3.198606774353613e-6 9.351917845713613e-6 4.181185325952435e-6 5290/90865/5525/3815/5526/207/5594/930/941/2064/4615/5528/2100/1950/4233/6714/2099/5519/8503/5159/2247/5529/2264/3630/2066/942/3654/7189/5527/2885/2246/5154/5518/5155/2252/1956/2549/5156/940/5595/5515/5516 42 Simian_virus_40 R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 21/2223 38/10654 3.2760258946946845e-6 9.55744945800058e-6 4.2730772539495885e-6 7020/4605/7021/3815/7422/4869/51741/2064/348/1026/2099/4609/10370/7341/1387/2033/7022/7329/1956/10765/7528 21 Simian_virus_40 R-HSA-73854 RNA Polymerase I Promoter Clearance 44/2223 110/10654 3.4611865817855522e-6 1.0075731871488527e-5 4.504798154167748e-6 5434/5440/902/9015/2648/2074/9112/9219/9014/25885/404672/5931/54700/5441/51082/11335/5435/7270/4331/9013/7343/1108/2966/8850/5928/5437/57459/2965/54815/64425/2068/3066/3065/2071/1107/2968/57504/84172/2967/6908/53615/1022/10919/5595 44 Simian_virus_40 R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 16/2223 25/10654 3.6011219984229592e-6 1.0415314055783645e-5 4.656623273822792e-6 5594/5528/5519/5598/1432/4208/6195/1385/6196/5518/6197/5600/51231/5595/5515/5516 16 Simian_virus_40 R-HSA-211981 Xenobiotics 16/2223 25/10654 3.6011219984229592e-6 1.0415314055783645e-5 4.656623273822792e-6 1576/1558/1559/1543/1544/1572/1548/1577/1571/1562/29785/1553/196/1557/405/1555 16 Simian_virus_40 R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 16/2223 25/10654 3.6011219984229592e-6 1.0415314055783645e-5 4.656623273822792e-6 1147/2308/2309/842/207/4303/1027/7249/1026/2932/3164/10000/208/2475/1385/4193 16 Simian_virus_40 R-HSA-111471 Apoptotic factor-mediated response 13/2223 18/10654 4.067457914339368e-6 1.1738771012996629e-5 5.248332792695959e-6 1029/842/5594/54205/56616/836/840/331/581/57099/317/578/5595 13 Simian_virus_40 R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 15/2223 23/10654 5.206020947060752e-6 1.4992446590033324e-5 6.703031262309982e-6 7321/6497/8239/7316/9611/9612/4089/4088/142/3065/6498/4087/6233/7311/7314 15 Simian_virus_40 R-HSA-211000 Gene Silencing by RNA 51/2223 136/10654 5.611230745108847e-6 1.6124778715066537e-5 7.209290036542417e-6 23165/27161/5434/5440/5903/55706/7175/9631/5430/5436/57690/27327/348995/79023/57122/5441/23636/192670/5438/10762/5431/23511/5435/54487/53371/5433/23279/4927/9688/79902/9883/5437/23225/3320/5439/192669/5901/8086/23112/29102/9972/8021/7257/6396/129401/26523/9271/5432/55746/23405/8480 51 Simian_virus_40 R-HSA-9020958 Interleukin-21 signaling 9/2223 10/10654 6.015304849628628e-6 1.7249015188464998e-5 7.711929294395677e-6 3561/6775/6776/50615/6774/6772/3716/6777/59067 9 Simian_virus_40 R-HSA-73864 RNA Polymerase I Transcription 44/2223 112/10654 6.051958728262769e-6 1.7317118578525878e-5 7.7423779039609e-6 5434/5440/902/9015/2648/2074/9112/9219/9014/25885/404672/5931/54700/5441/51082/11335/5435/7270/4331/9013/7343/1108/2966/8850/5928/5437/57459/2965/54815/64425/2068/3066/3065/2071/1107/2968/57504/84172/2967/6908/53615/1022/10919/5595 44 Simian_virus_40 R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 11/2223 14/10654 6.185634804882629e-6 1.7587122686763746e-5 7.863095090952493e-6 2801/5594/5861/9133/891/26003/983/8615/81876/5347/5595 11 Simian_virus_40 R-HSA-198323 AKT phosphorylates targets in the cytosol 11/2223 14/10654 6.185634804882629e-6 1.7587122686763746e-5 7.863095090952493e-6 1147/842/207/1027/7249/1026/2932/10000/208/23608/4193 11 Simian_virus_40 R-HSA-877312 Regulation of IFNG signaling 11/2223 14/10654 6.185634804882629e-6 1.7587122686763746e-5 7.863095090952493e-6 3460/9021/6772/8651/3459/7341/3717/5771/3458/3716/8554 11 Simian_virus_40 R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 10/2223 12/10654 6.684394248171795e-6 1.8925014938916768e-5 8.461258541989615e-6 834/58484/55367/472/843/7157/8626/7161/839/317 10 Simian_virus_40 R-HSA-8984722 Interleukin-35 Signalling 10/2223 12/10654 6.684394248171795e-6 1.8925014938916768e-5 8.461258541989615e-6 3592/6775/3595/6774/6772/3717/9466/3716/7297/3572 10 Simian_virus_40 R-HSA-6784531 tRNA processing in the nucleus 27/2223 57/10654 6.84173690317094e-6 1.932970720853769e-5 8.642193982952766e-6 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/1653/9972/8021/6396/129401/55746/8480 27 Simian_virus_40 R-HSA-8848021 Signaling by PTK6 26/2223 54/10654 6.943343225170867e-6 1.953452119115158e-5 8.733765063108009e-6 120892/1017/1019/4893/207/9021/27043/1027/898/3091/2064/5921/7316/1950/6774/2908/595/2066/6233/1398/9844/7311/1956/3845/3265/7314 26 Simian_virus_40 R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 26/2223 54/10654 6.943343225170867e-6 1.953452119115158e-5 8.733765063108009e-6 120892/1017/1019/4893/207/9021/27043/1027/898/3091/2064/5921/7316/1950/6774/2908/595/2066/6233/1398/9844/7311/1956/3845/3265/7314 26 Simian_virus_40 R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 19/2223 34/10654 7.752514523727819e-6 2.176542780511032e-5 9.731189778737849e-6 7321/9636/7706/9474/7316/3093/7128/54941/83737/3661/9246/51191/6233/7311/55593/7318/5300/1540/7314 19 Simian_virus_40 R-HSA-72766 Translation 92/2223 291/10654 8.718324955031447e-6 2.4425870750839668e-5 1.0920657563713712e-5 6158/6138/6144/5464/6203/9349/4736/6206/6194/6191/6128/51121/6132/1938/6147/56945/8666/6129/1915/6217/6222/6152/6136/79590/8668/64432/27068/8667/6125/6154/51065/8662/6141/10480/26986/6202/65003/6232/6160/6155/63931/6175/6218/6728/9669/6209/6231/6229/6130/6142/6204/64969/54148/23107/8894/7965/140801/23438/6156/6143/6181/55173/6124/28973/6207/64978/51116/6233/28957/64975/7311/6223/3646/51386/3921/6188/6189/8665/6135/6201/1978/9045/51649/6187/64965/6168/6208/6137/1974/6122/55037/6230 92 Simian_virus_40 R-HSA-165159 mTOR signalling 21/2223 40/10654 9.66228095363168e-6 2.701412716619524e-5 1.20778511920396e-5 5563/6194/389541/207/51422/7249/53632/6198/5571/6794/6009/208/10542/2475/55004/5562/1978/5564/5565/57521/7529 21 Simian_virus_40 R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 17/2223 29/10654 9.847197409035554e-6 2.747388549464805e-5 1.2283406331437283e-5 2308/2309/4303/23410/4287/6720/847/4089/4088/2908/3630/3066/3065/6648/4087/25942/10891 17 Simian_virus_40 R-HSA-1236394 Signaling by ERBB4 27/2223 58/10654 1.0274618036211108e-5 2.8606924075923874e-5 1.278998095793914e-5 4893/5290/5241/6678/51741/348/6776/7316/1950/9611/10413/6714/2099/2567/2066/83737/3925/6285/6233/2885/7311/1956/3845/3265/5663/7314/6387 27 Simian_virus_40 R-HSA-450302 activated TAK1 mediates p38 MAPK activation 15/2223 24/10654 1.1202111142484424e-5 3.093257850455576e-5 1.3829766842573364e-5 6885/5606/8517/7316/64127/1432/3656/10454/3654/7189/6233/7311/5600/7334/7314 15 Simian_virus_40 R-HSA-5260271 Diseases of Immune System 15/2223 24/10654 1.1202111142484424e-5 3.093257850455576e-5 1.3829766842573364e-5 1147/81793/4790/10333/7099/8517/4615/7098/7100/5970/4792/7096/81622/7097/3551 15 Simian_virus_40 R-HSA-5602358 Diseases associated with the TLR signaling cascade 15/2223 24/10654 1.1202111142484424e-5 3.093257850455576e-5 1.3829766842573364e-5 1147/81793/4790/10333/7099/8517/4615/7098/7100/5970/4792/7096/81622/7097/3551 15 Simian_virus_40 R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 15/2223 24/10654 1.1202111142484424e-5 3.093257850455576e-5 1.3829766842573364e-5 596/2309/5747/207/5594/1027/1950/10000/595/208/7514/1385/2353/1956/5595 15 Simian_virus_40 R-HSA-5673000 RAF activation 18/2223 32/10654 1.1919043132668683e-5 3.2844673273185575e-5 1.4684652730187292e-5 4893/5525/5526/5528/6714/5519/3717/5529/5894/5527/5518/3845/3265/369/5245/7529/5515/5516 18 Simian_virus_40 R-HSA-166520 Signaling by NTRKs 40/2223 101/10654 1.2595512401337149e-5 3.463765910367716e-5 1.5486285739348954e-5 627/4893/5290/5335/2904/5594/5528/6774/6714/5519/5598/1432/4208/4914/6195/5603/2885/1398/1385/6196/5518/1213/1211/8851/581/6197/3845/5600/2549/3265/1399/6300/1020/51231/7529/5595/5515/25920/5516/5607 40 Simian_virus_40 R-HSA-432142 Platelet sensitization by LDL 12/2223 17/10654 1.4239800942039422e-5 3.907937191046402e-5 1.7472148395140395e-5 5525/5526/338/5528/5519/1432/5529/5527/7804/5518/5515/5516 12 Simian_virus_40 R-HSA-380108 Chemokine receptors bind chemokines 27/2223 59/10654 1.5207197806930014e-5 4.164910093244914e-5 1.8621058539097977e-5 729230/57007/7852/6351/6374/1230/2919/6367/6349/3576/2920/1236/6352/6348/6354/3627/6364/9034/1524/4283/6363/6347/2833/6356/6361/1234/6387 27 Simian_virus_40 R-HSA-9612973 Autophagy 45/2223 119/10654 1.527744131522348e-5 4.1756265264826704e-5 1.866897105729957e-5 5563/64422/1459/1915/389541/8878/9821/51422/7249/8897/1080/1460/10533/10013/53632/7416/9474/7316/8655/1457/8678/6714/3043/5571/3320/128866/6009/81631/10542/6233/3326/2475/55004/7311/5562/7251/7431/3312/5564/11315/23192/5565/57521/140735/7314 45 Simian_virus_40 R-HSA-2024096 HS-GAG degradation 14/2223 22/10654 1.649777038725497e-5 4.500001597499221e-5 2.0119232179579235e-5 6385/2817/375790/3339/6383/221914/2262/2239/60495/10855/6382/9672/2719/10082 14 Simian_virus_40 R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 34/2223 82/10654 1.774233162208038e-5 4.819880371828314e-5 2.1549390634105727e-5 10844/115106/22995/22981/7531/203068/7532/1454/7277/5048/1781/8655/983/7846/7283/3320/22919/80097/10540/10733/1069/4751/54930/5518/10383/55835/54820/5347/9662/23332/1453/9793/8481/1778 34 Simian_virus_40 R-HSA-380287 Centrosome maturation 34/2223 82/10654 1.774233162208038e-5 4.819880371828314e-5 2.1549390634105727e-5 10844/115106/22995/22981/7531/203068/7532/1454/7277/5048/1781/8655/983/7846/7283/3320/22919/80097/10540/10733/1069/4751/54930/5518/10383/55835/54820/5347/9662/23332/1453/9793/8481/1778 34 Simian_virus_40 R-HSA-4090294 SUMOylation of intracellular receptors 17/2223 30/10654 1.831460143969887e-5 4.945310891765772e-5 2.2110182824586165e-5 7068/5241/5468/51588/6613/5465/8856/2099/7341/10401/2908/7329/367/6612/9063/7421/8554 17 Simian_virus_40 R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 17/2223 30/10654 1.831460143969887e-5 4.945310891765772e-5 2.2110182824586165e-5 11065/7319/7321/65264/7320/8239/7316/7317/3093/7347/29089/6233/7327/7311/7874/7332/7314 17 Simian_virus_40 R-HSA-8874081 MET activates PTK2 signaling 17/2223 30/10654 1.831460143969887e-5 4.945310891765772e-5 2.2110182824586165e-5 3918/5747/3911/284217/1277/3912/3688/4233/3915/6714/3910/3673/3908/2335/3909/3913/10319 17 Simian_virus_40 R-HSA-5578749 Transcriptional regulation by small RNAs 41/2223 106/10654 1.929261317781419e-5 5.1989331093627795e-5 2.3244112262426734e-5 23165/27161/5434/5440/5903/55706/7175/9631/5430/5436/27327/348995/79023/57122/5441/23636/5438/10762/5431/23511/5435/53371/5433/23279/4927/9688/79902/9883/5437/23225/5439/5901/8086/9972/8021/6396/129401/26523/5432/55746/8480 41 Simian_virus_40 R-HSA-5357905 Regulation of TNFR1 signaling 18/2223 33/10654 2.1122377695350404e-5 5.6806073882084645e-5 2.539764853148345e-5 7124/1147/7375/330/841/27005/8517/7316/7128/7132/329/10616/6233/7311/331/1540/3551/7314 18 Simian_virus_40 R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 15/2223 25/10654 2.2603594858576802e-5 6.066804860042014e-5 2.7124313830292164e-5 10694/51807/10575/7277/7203/10576/908/6950/7846/10574/10383/84790/22948/10693/7280 15 Simian_virus_40 R-HSA-111461 Cytochrome c-mediated apoptotic response 10/2223 13/10654 2.3511595377023543e-5 6.272874949496143e-5 2.8045640608775604e-5 842/5594/54205/56616/836/840/331/57099/317/5595 10 Simian_virus_40 R-HSA-209543 p75NTR recruits signalling complexes 10/2223 13/10654 2.3511595377023543e-5 6.272874949496143e-5 2.8045640608775604e-5 4804/8878/4615/7316/3654/7189/6233/7311/3551/7314 10 Simian_virus_40 R-HSA-68884 Mitotic Telophase/Cytokinesis 10/2223 13/10654 2.3511595377023543e-5 6.272874949496143e-5 2.8045640608775604e-5 10274/23244/10735/23047/5885/10112/8243/9126/5347/9493 10 Simian_virus_40 R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 13/2223 20/10654 2.4052129545860987e-5 6.379043053467479e-5 2.852031171445967e-5 1147/7321/330/8517/7098/7316/329/7189/6233/7311/7334/3551/7314 13 Simian_virus_40 R-HSA-622312 Inflammasomes 13/2223 20/10654 2.4052129545860987e-5 6.379043053467479e-5 2.852031171445967e-5 834/596/351/4790/10910/58484/7295/29108/5970/24145/598/10628/3326 13 Simian_virus_40 R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 13/2223 20/10654 2.4052129545860987e-5 6.379043053467479e-5 2.852031171445967e-5 2648/23462/3280/22938/8850/1387/4088/59/2033/4855/9794/3516/4851 13 Simian_virus_40 R-HSA-187037 Signaling by NTRK1 (TRKA) 33/2223 80/10654 2.6650817907213638e-5 7.05431905946365e-5 3.1539429475992466e-5 4893/5290/5335/5594/5528/6774/6714/5519/5598/1432/4208/4914/6195/5603/2885/1398/1385/6196/5518/1213/1211/6197/3845/5600/3265/1399/6300/51231/7529/5595/5515/5516/5607 33 Simian_virus_40 R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 78/2223 244/10654 2.6894997157305908e-5 7.065894445335348e-5 3.1591182318935986e-5 23165/23451/2963/5434/5440/5903/6431/6627/55706/7175/24148/9631/5430/4904/5436/27238/55749/3178/348995/79023/57122/5441/23636/5438/10762/5431/9092/5093/23511/5435/10594/10713/53371/1655/9343/3185/3190/5433/56339/24144/23279/4927/9688/79902/2962/22938/9883/9984/5437/4670/23225/23658/10189/10482/10949/3181/5439/8086/3191/6638/3187/9972/53938/6634/8021/3192/6396/129401/3312/6426/5432/55746/11100/8480/10992/55339/10262/1994 78 Simian_virus_40 R-HSA-1059683 Interleukin-6 signaling 9/2223 11/10654 2.6905156941627148e-5 7.065894445335348e-5 3.1591182318935986e-5 9021/6774/6772/3717/3716/3570/7297/3569/3572 9 Simian_virus_40 R-HSA-211999 CYP2E1 reactions 9/2223 11/10654 2.6905156941627148e-5 7.065894445335348e-5 3.1591182318935986e-5 1558/1559/1572/1548/1571/29785/1553/1557/1555 9 Simian_virus_40 R-HSA-4755510 SUMOylation of immune response proteins 9/2223 11/10654 2.6905156941627148e-5 7.065894445335348e-5 3.1591182318935986e-5 51588/8517/10210/5970/4792/7341/10401/7329/6612 9 Simian_virus_40 R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 37/2223 94/10654 3.089256832050226e-5 8.097231774631646e-5 3.6202228500588585e-5 10844/115106/22995/22981/7531/203068/51807/7532/1454/7277/5048/1781/8655/983/7846/7283/3320/22919/80097/10540/10733/1069/4751/54930/5518/10383/55835/54820/5347/84790/9662/23332/1453/9793/8481/7280/1778 37 Simian_virus_40 R-HSA-5675482 Regulation of necroptotic cell death 12/2223 18/10654 3.458448699743963e-5 9.045482130998732e-5 4.0441797903123985e-5 355/330/841/7316/8797/329/8837/6233/7311/331/8795/7314 12 Simian_virus_40 R-HSA-70326 Glucose metabolism 36/2223 91/10654 3.4645140203676215e-5 9.045482130998732e-5 4.0441797903123985e-5 23165/5903/2597/55706/7175/9631/5315/348995/79023/57122/23636/10762/23511/5528/53371/5230/23279/4927/9688/79902/5519/9883/23225/2821/4190/8086/9972/5518/8021/6396/129401/230/55746/8480/5515/5516 36 Simian_virus_40 R-HSA-72165 mRNA Splicing - Minor Pathway 24/2223 52/10654 3.771673229444131e-5 9.82832130857092e-5 4.394182403235881e-5 23451/2963/5434/5440/6431/24148/5430/4904/5436/5441/5438/5431/5435/10594/9343/5433/2962/5437/5439/6634/6426/5432/10992/10262 24 Simian_virus_40 R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 19/2223 37/10654 3.852828146695722e-5 1.0020339869894688e-4 4.480032728715956e-5 27161/8841/344/57690/27327/192670/348/9611/2874/9612/2033/192669/9682/23028/23112/4343/1071/26523/8648 19 Simian_virus_40 R-HSA-2173788 Downregulation of TGF-beta receptor signaling 15/2223 26/10654 4.3133169686708215e-5 1.119626957825192e-4 5.005783716058981e-5 57154/10273/7316/5501/4092/4088/9958/4087/5499/6233/7514/7311/7040/5500/7314 15 Simian_virus_40 R-HSA-1295596 Spry regulation of FGF signaling 11/2223 16/10654 4.8769067866508955e-5 1.261042178744798e-4 5.638042527920111e-5 5594/7316/6714/6233/2885/7311/5518/7314/5595/5515/5516 11 Simian_virus_40 R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 11/2223 16/10654 4.8769067866508955e-5 1.261042178744798e-4 5.638042527920111e-5 1147/8945/4790/6500/8517/7316/23291/6233/7311/3551/7314 11 Simian_virus_40 R-HSA-1227986 Signaling by ERBB2 23/2223 50/10654 5.8203970742921836e-5 1.502110168019252e-4 6.715842778029443e-5 4893/5290/5335/10273/207/5578/2064/7316/1950/6714/10000/3320/2066/208/6233/2885/5580/7311/1956/3845/2549/3265/7314 23 Simian_virus_40 R-HSA-5689896 Ovarian tumor domain proteases 19/2223 38/10654 6.206503575877223e-5 1.598680959467799e-4 7.14760488584709e-5 7321/55611/7706/8517/7316/983/2099/79589/7415/64127/7128/5728/7157/7189/6233/7311/55593/78990/7314 19 Simian_virus_40 R-HSA-5654743 Signaling by FGFR4 20/2223 41/10654 6.266230980295468e-5 1.6109735585357314e-4 7.202564345167205e-5 4893/5290/5335/5594/7316/6714/2247/2264/6233/2885/2246/7311/5518/3845/2549/3265/7314/5595/5515/5516 20 Simian_virus_40 R-HSA-933542 TRAF6 mediated NF-kB activation 14/2223 24/10654 6.60675579066587e-5 1.6952707975284123e-4 7.579452149903485e-5 1147/351/4790/4214/7706/8517/5970/4792/4793/3146/6288/7189/6285/3551 14 Simian_virus_40 R-HSA-162594 Early Phase of HIV Life Cycle 10/2223 14/10654 6.68264968073759e-5 1.7082125469618757e-4 7.637313920842961e-5 2237/7852/3159/7518/7520/3978/3981/5478/2547/1234 10 Simian_virus_40 R-HSA-8941856 RUNX3 regulates NOTCH signaling 10/2223 14/10654 6.68264968073759e-5 1.7082125469618757e-4 7.637313920842961e-5 2648/864/3280/22938/8850/1387/2033/9794/3516/4851 10 Simian_virus_40 R-HSA-912526 Interleukin receptor SHC signaling 15/2223 27/10654 7.837290216518202e-5 1.9995519906021726e-4 8.939874771693768e-5 3562/5290/1437/3561/3568/1438/3560/8503/3567/3558/3717/3563/2885/3716/3559 15 Simian_virus_40 R-HSA-176974 Unwinding of DNA 9/2223 12/10654 8.756744502199321e-5 2.2256725609756607e-4 9.950846025226502e-5 4172/8318/4173/4174/84515/4171/4175/51659/4176 9 Simian_virus_40 R-HSA-264870 Caspase-mediated cleavage of cytoskeletal proteins 9/2223 12/10654 8.756744502199321e-5 2.2256725609756607e-4 9.950846025226502e-5 2934/118/841/5339/28988/836/839/840/7431 9 Simian_virus_40 R-HSA-1839126 FGFR2 mutant receptor activation 17/2223 33/10654 9.353918700588087e-5 2.3729600937975827e-4 1.0609359584788e-4 2963/5434/5440/5430/5436/5441/5438/5431/5435/5433/2962/5437/2247/5439/2246/2252/5432 17 Simian_virus_40 R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 19/2223 39/10654 9.750053279110252e-5 2.4687870755784827e-4 1.1037796165030475e-4 10694/9134/8841/8237/10575/898/7203/10576/908/6774/26272/26270/6950/55294/10238/7157/10574/22948/10693 19 Simian_virus_40 R-HSA-1632852 Macroautophagy 36/2223 95/10654 1.0011993663348229e-4 2.5303381348800987e-4 1.1312987190223988e-4 5563/64422/1459/389541/8878/9821/51422/7249/8897/1460/10533/53632/7416/9474/7316/8655/1457/8678/6714/5571/128866/6009/81631/10542/6233/2475/55004/7311/5562/3312/5564/23192/5565/57521/140735/7314 36 Simian_virus_40 R-HSA-9613829 Chaperone Mediated Autophagy 13/2223 22/10654 1.0100025005915183e-4 2.547788262770334e-4 1.1391005645769004e-4 1915/1080/10013/7316/3043/3320/6233/3326/7311/7431/3312/11315/7314 13 Simian_virus_40 R-HSA-186797 Signaling by PDGF 25/2223 58/10654 1.0568596934086241e-4 2.6590035107683114e-4 1.1888242224001393e-4 1282/4893/5290/5335/5340/1284/5921/6778/6696/6776/6774/6772/6714/5159/2885/1398/5154/5155/3845/6777/3265/1399/7057/56034/5156 25 Simian_virus_40 R-HSA-110056 MAPK3 (ERK1) activation 8/2223 10/10654 1.0639976790481246e-4 2.6590035107683114e-4 1.1888242224001393e-4 983/3717/3716/3570/7297/3569/3572/5595 8 Simian_virus_40 R-HSA-5685939 HDR through MMEJ (alt-NHEJ) 8/2223 10/10654 1.0639976790481246e-4 2.6590035107683114e-4 1.1888242224001393e-4 2237/10111/7515/4683/142/5932/3980/10038 8 Simian_virus_40 R-HSA-8877330 RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) 8/2223 10/10654 1.0639976790481246e-4 2.6590035107683114e-4 1.1888242224001393e-4 4773/865/3558/50943/3458/8784/3559/1493 8 Simian_virus_40 R-HSA-937042 IRAK2 mediated activation of TAK1 complex 8/2223 10/10654 1.0639976790481246e-4 2.6590035107683114e-4 1.1888242224001393e-4 6885/7316/3656/10454/7189/6233/7311/7314 8 Simian_virus_40 R-HSA-5250913 Positive epigenetic regulation of rRNA expression 39/2223 106/10654 1.1076802937792263e-4 2.7630240785347986e-4 1.2353311826534123e-4 8467/23451/5434/5440/9015/10514/2648/2074/9112/9219/9014/25885/5931/5441/51082/11335/5435/9031/7270/9013/4641/1108/8850/5928/2932/5437/57459/54815/2033/64425/3066/3065/1107/57504/84172/6908/60/53615/10919 39 Simian_virus_40 R-HSA-73884 Base Excision Repair 35/2223 92/10654 1.134671828844851e-4 2.825101288144323e-4 1.2630855237605023e-4 11284/7014/6118/25913/2237/328/57804/4913/7515/5982/54107/7013/3978/6996/5425/26277/5111/5426/6119/5427/5985/65057/142/5984/4595/4968/3980/55247/5983/6117/5981/10038/10714/5424/56655 35 Simian_virus_40 R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 30/2223 75/10654 1.1996180505590586e-4 2.981273007130105e-4 1.3329089450656208e-4 23165/5903/6431/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/9984/23225/10189/10482/8086/9972/8021/6396/129401/6426/55746/8480 30 Simian_virus_40 R-HSA-1643713 Signaling by EGFR in Cancer 14/2223 25/10654 1.213853290587633e-4 2.99446896317758e-4 1.338808776383419e-4 4893/5290/5335/7316/1950/3320/6233/2885/7311/1956/3845/2549/3265/7314 14 Simian_virus_40 R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 14/2223 25/10654 1.213853290587633e-4 2.99446896317758e-4 1.338808776383419e-4 11065/7321/991/8881/7316/4085/4751/6233/701/7311/9184/29882/7314/996 14 Simian_virus_40 R-HSA-429947 Deadenylation of mRNA 14/2223 25/10654 1.213853290587633e-4 2.99446896317758e-4 1.338808776383419e-4 9924/4849/4850/26986/9337/25904/246175/4848/23019/55571/57472/85456/29883/1974 14 Simian_virus_40 R-HSA-9006335 Signaling by Erythropoietin 14/2223 25/10654 1.213853290587633e-4 2.99446896317758e-4 1.338808776383419e-4 4893/5290/5335/5336/6776/4067/3717/2885/2056/3845/2549/6777/3265/1399 14 Simian_virus_40 R-HSA-9012852 Signaling by NOTCH3 22/2223 49/10654 1.3119146446568985e-4 3.2304393635404727e-4 1.444309700539705e-4 2648/23462/4904/3280/10460/7316/1950/4854/6772/22938/8850/1387/2033/9794/6233/7311/1956/9787/3516/4851/5663/7314 22 Simian_virus_40 R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 15/2223 28/10654 1.3635619080499785e-4 3.351465349089874e-4 1.4984196791758007e-4 10694/10575/7277/7203/10576/908/6950/7846/10574/10383/60/84790/22948/10693/7280 15 Simian_virus_40 R-HSA-75893 TNF signaling 20/2223 43/10654 1.4503881628175682e-4 3.558356333640177e-4 1.590919374205742e-4 7124/1147/6885/7375/330/841/27005/8517/7316/7128/7132/329/10616/10454/6233/7311/331/1540/3551/7314 20 Simian_virus_40 R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 16/2223 31/10654 1.460070948157158e-4 3.5755752051585876e-4 1.5986178264494432e-4 857/1499/5525/1856/5526/1452/5528/5519/2932/1455/8312/5529/5527/5518/5515/5516 16 Simian_virus_40 R-HSA-5693571 Nonhomologous End-Joining (NHEJ) 28/2223 69/10654 1.4930778516742532e-4 3.6497458596481747e-4 1.6317790728680366e-4 10111/51588/7518/7520/51720/472/7336/3981/580/5591/29086/64421/9656/22976/7341/10524/4683/55775/165918/8924/672/7158/9025/79184/7334/2547/79840/55183 28 Simian_virus_40 R-HSA-5654741 Signaling by FGFR3 19/2223 40/10654 1.4964538915347643e-4 3.6513474953448247e-4 1.6324951544015613e-4 4893/5290/5335/5594/7316/6714/2247/6233/2885/2246/7311/5518/3845/2549/3265/7314/5595/5515/5516 19 Simian_virus_40 R-HSA-5213460 RIPK1-mediated regulated necrosis 12/2223 20/10654 1.5398237713109598e-4 3.7435570672088916e-4 1.6737214905553912e-4 355/330/841/7316/8797/329/8837/6233/7311/331/8795/7314 12 Simian_virus_40 R-HSA-5218859 Regulated Necrosis 12/2223 20/10654 1.5398237713109598e-4 3.7435570672088916e-4 1.6737214905553912e-4 355/330/841/7316/8797/329/8837/6233/7311/331/8795/7314 12 Simian_virus_40 R-HSA-2162123 Synthesis of Prostaglandins (PG) and Thromboxanes (TX) 10/2223 15/10654 1.6288299005831765e-4 3.931456342774502e-4 1.7577301085429964e-4 5730/5743/8644/5740/9536/80142/27306/6916/5742/10728 10 Simian_virus_40 R-HSA-5637810 Constitutive Signaling by EGFRvIII 10/2223 15/10654 1.6288299005831765e-4 3.931456342774502e-4 1.7577301085429964e-4 4893/5290/5335/1950/3320/2885/1956/3845/2549/3265 10 Simian_virus_40 R-HSA-5637812 Signaling by EGFRvIII in Cancer 10/2223 15/10654 1.6288299005831765e-4 3.931456342774502e-4 1.7577301085429964e-4 4893/5290/5335/1950/3320/2885/1956/3845/2549/3265 10 Simian_virus_40 R-HSA-844456 The NLRP3 inflammasome 10/2223 15/10654 1.6288299005831765e-4 3.931456342774502e-4 1.7577301085429964e-4 834/351/4790/10910/7295/29108/5970/24145/10628/3326 10 Simian_virus_40 R-HSA-73887 Death Receptor Signalling 48/2223 141/10654 1.7709809801342942e-4 4.266887747468982e-4 1.907699440001035e-4 7124/1147/4804/8841/4790/6885/10018/7531/29/8793/7375/8878/1894/355/330/23421/841/27005/8517/4615/9500/7316/9828/5970/4792/8797/7128/7132/329/843/836/10616/8837/10454/3066/3065/3654/7189/6233/7311/26574/331/5599/1540/3551/8795/5663/7314 48 Simian_virus_40 R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK 15/2223 29/10654 2.2822581696158953e-4 5.488871798610271e-4 2.454041042597737e-4 5563/389541/51422/7249/53632/5571/6794/6009/10542/2475/55004/5562/5564/5565/57521 15 Simian_virus_40 R-HSA-202670 ERKs are inactivated 9/2223 13/10654 2.3169310672317462e-4 5.562292472674424e-4 2.486866977350712e-4 5594/5528/5519/5598/5518/51231/5595/5515/5516 9 Simian_virus_40 R-HSA-2871796 FCERI mediated MAPK activation 16/2223 32/10654 2.357806316643092e-4 5.640242561381514e-4 2.5217179857145374e-4 3725/5601/4893/5335/5336/5594/4214/4067/5602/5609/2885/2353/3845/5599/3265/5595 16 Simian_virus_40 R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 16/2223 32/10654 2.357806316643092e-4 5.640242561381514e-4 2.5217179857145374e-4 10694/51807/10575/7277/7203/10576/908/6950/7846/10574/10383/60/84790/22948/10693/7280 16 Simian_virus_40 R-HSA-5218921 VEGFR2 mediated cell proliferation 12/2223 21/10654 2.91202924483667e-4 6.953635670054824e-4 3.10892801939858e-4 5590/4893/5335/5579/7422/5578/5921/6714/5580/3791/3845/3265 12 Simian_virus_40 R-HSA-157579 Telomere Maintenance 31/2223 82/10654 3.1158312616440617e-4 7.427079135215507e-4 3.3206016997982895e-4 7014/6118/25913/2237/7015/1763/57804/5982/54107/7013/3978/5557/5422/10856/5425/26277/5111/5426/6119/5427/5985/65057/5984/23649/5983/6117/5981/10714/5558/5424/56655 31 Simian_virus_40 R-HSA-111458 Formation of apoptosome 8/2223 11/10654 3.1838539713997273e-4 7.496021104593744e-4 3.3514252330523446e-4 842/5594/54205/56616/331/57099/317/5595 8 Simian_virus_40 R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 8/2223 11/10654 3.1838539713997273e-4 7.496021104593744e-4 3.3514252330523446e-4 7422/3091/10370/1387/2033/2056/405/768 8 Simian_virus_40 R-HSA-2468052 Establishment of Sister Chromatid Cohesion 8/2223 11/10654 3.1838539713997273e-4 7.496021104593744e-4 3.3514252330523446e-4 10274/23244/10735/23047/5885/8243/9126/113130 8 Simian_virus_40 R-HSA-5655291 Signaling by FGFR4 in disease 8/2223 11/10654 3.1838539713997273e-4 7.496021104593744e-4 3.3514252330523446e-4 4893/5290/5335/2264/2885/3845/2549/3265 8 Simian_virus_40 R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 8/2223 11/10654 3.1838539713997273e-4 7.496021104593744e-4 3.3514252330523446e-4 6885/7098/7316/10454/7189/6233/7311/7314 8 Simian_virus_40 R-HSA-9020956 Interleukin-27 signaling 8/2223 11/10654 3.1838539713997273e-4 7.496021104593744e-4 3.3514252330523446e-4 6774/6772/3717/9466/3716/246778/7297/3572 8 Simian_virus_40 R-HSA-9627069 Regulation of the apoptosome activity 8/2223 11/10654 3.1838539713997273e-4 7.496021104593744e-4 3.3514252330523446e-4 842/5594/54205/56616/331/57099/317/5595 8 Simian_virus_40 R-HSA-186712 Regulation of beta-cell development 19/2223 42/10654 3.308701991036618e-4 7.762723902047451e-4 3.4706664241642847e-4 2308/2648/3172/3171/207/3280/22938/8850/1387/10000/2033/3630/6514/208/9794/3375/5080/3516/4851 19 Simian_virus_40 R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 19/2223 42/10654 3.308701991036618e-4 7.762723902047451e-4 3.4706664241642847e-4 9070/8945/1487/1499/207/5929/6657/7534/7316/3065/208/57680/6233/7514/7311/331/6659/7314/4221 19 Simian_virus_40 R-HSA-205043 NRIF signals cell death from the nucleus 10/2223 16/10654 3.530728603779987e-4 8.269175892273546e-4 3.6970980144293054e-4 4804/8878/23421/7316/7189/6233/7311/5599/5663/7314 10 Simian_virus_40 R-HSA-5423646 Aflatoxin activation and detoxification 11/2223 19/10654 4.5083657480119544e-4 0.001054046486730321 4.712577436946294e-4 1576/4258/4257/1544/2687/4259/1577/2686/2678/1553/22977 11 Simian_virus_40 R-HSA-5620912 Anchoring of the basal body to the plasma membrane 35/2223 98/10654 4.686254617077347e-4 0.0010937310775857043 4.890004817819841e-4 115106/22995/22981/7531/80776/203068/7532/1454/7277/5048/1781/22832/8655/983/7846/7283/3320/22919/10540/10733/1069/4751/54930/5518/10383/55835/54820/5347/23322/9662/23332/1453/9793/8481/1778 35 Simian_virus_40 R-HSA-72202 Transport of Mature Transcript to Cytoplasm 31/2223 84/10654 5.083140452986876e-4 0.001184301126372984 5.294937971861329e-4 23165/5903/6431/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/9984/23225/10189/10482/8086/9972/8021/6396/129401/6426/55746/8480/55339 31 Simian_virus_40 R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 13/2223 25/10654 5.604649228565746e-4 0.0013012870700233963 5.81797497774991e-4 2648/23462/3280/4854/6772/22938/8850/1387/2033/9794/9787/3516/4851 13 Simian_virus_40 R-HSA-937041 IKK complex recruitment mediated by RIP1 13/2223 25/10654 5.604649228565746e-4 0.0013012870700233963 5.81797497774991e-4 1147/7321/330/7099/8517/7316/329/7189/6233/7311/7334/3551/7314 13 Simian_virus_40 R-HSA-4791275 Signaling by WNT in cancer 16/2223 34/10654 5.640905167601566e-4 0.0013074429593991886 5.845497583006805e-4 27123/1487/1499/5525/5526/1452/5528/5519/2932/54894/8312/5529/5527/5518/5515/5516 16 Simian_virus_40 R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 38/2223 110/10654 5.816198210216032e-4 0.0013457479307086059 6.016756769188998e-4 1017/3725/1019/11065/4790/1029/7321/5594/1027/1051/79813/3576/8881/7316/890/6774/5970/1026/1031/5598/3552/1021/6195/8900/6233/1032/2353/1030/51343/6196/7311/6197/29882/3569/10919/7314/996/5595 38 Simian_virus_40 R-HSA-9024446 NR1H2 and NR1H3-mediated signaling 20/2223 47/10654 6.214310606465821e-4 0.0014353880953316923 6.417532467950935e-4 27161/8841/344/57690/27327/6720/192670/348/9611/2874/9612/2033/192669/9682/23028/23112/4343/1071/26523/8648 20 Simian_virus_40 R-HSA-983231 Factors involved in megakaryocyte development and platelet production 53/2223 168/10654 7.049434915581119e-4 0.0016254882571666428 7.267458675856824e-4 1017/23468/25/85440/5868/23186/51807/2625/3047/29127/3832/7277/81928/91768/832/3659/3796/3043/10112/1062/3705/5889/3717/7846/146909/56992/4602/3066/3065/998/7157/7975/23028/3439/11004/3835/3833/10383/24137/51317/60/25942/84790/5890/84643/9493/7465/3456/1020/81704/81930/7280/829 53 Simian_virus_40 R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 21/2223 51/10654 7.75125094933066e-4 0.0017842502185251706 7.977273704285413e-4 1783/51807/5050/7277/1780/5048/1781/8398/8655/832/636/7846/51143/10540/10383/84790/5049/140735/7280/829/1778 21 Simian_virus_40 R-HSA-5689877 Josephin domain DUBs 8/2223 12/10654 7.800213013759335e-4 0.0017924462096686692 8.013917479889728e-4 4287/7316/7415/6233/7311/5887/5886/7314 8 Simian_virus_40 R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 12/2223 23/10654 8.810029557634835e-4 0.0020210358404010166 9.035927751420345e-4 11065/7321/991/8881/7316/891/983/6233/7311/29882/7314/996 12 Simian_virus_40 R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 14/2223 29/10654 9.049945707699798e-4 0.002072530228623401 9.266156014709692e-4 5434/5440/5430/5436/5441/5438/5431/5435/5433/5437/3320/5439/9271/5432 14 Simian_virus_40 R-HSA-8866910 TFAP2 (AP-2) family regulates transcription of growth factors and their receptors 9/2223 15/10654 0.0010768080263415553 0.002461799610477627 0.0011006555635518452 7020/7021/3815/7422/2064/2099/7022/1956/7528 9 Simian_virus_40 R-HSA-2470946 Cohesin Loading onto Chromatin 7/2223 10/10654 0.0011246195502058257 0.00256237595310054 0.001145622631788617 10274/23244/10735/23047/5885/8243/9126 7 Simian_virus_40 R-HSA-3215018 Processing and activation of SUMO 7/2223 10/10654 0.0011246195502058257 0.00256237595310054 0.001145622631788617 10054/29843/6613/7341/10055/7329/6612 7 Simian_virus_40 R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 22/2223 56/10654 0.0012415545759994272 0.0028240105779512394 0.0012625978738977227 5442/8841/23408/23410/200186/5465/9611/5469/23409/54205/4208/1387/6604/6648/10498/1385/10499/23054/1386/7019/8648/10891 22 Simian_virus_40 R-HSA-8856688 Golgi-to-ER retrograde transport 43/2223 133/10654 0.0012545719189565538 0.002848791057935187 0.0012736770750827959 60561/1783/51807/5050/29127/5861/3832/7277/1780/5048/1781/8398/8655/832/3796/81876/9183/10112/11316/636/1062/7846/146909/56992/8729/51143/10540/11004/3835/3833/10383/24137/84790/84643/9493/5049/81930/140735/7280/54732/829/1778/22818 43 Simian_virus_40 R-HSA-1368082 RORA activates gene expression 10/2223 18/10654 0.001276757290058801 0.0028942707487481607 0.0012940107669514877 6720/5465/5469/1387/6604/2033/10498/10499/23054/8648 10 Simian_virus_40 R-HSA-6783589 Interleukin-6 family signaling 12/2223 24/10654 0.0014298623774452496 0.003230429815709638 0.0014443054317628786 9180/9021/3976/6774/6772/3717/3716/3570/3977/7297/3569/3572 12 Simian_virus_40 R-HSA-982772 Growth hormone receptor signaling 12/2223 24/10654 0.0014298623774452496 0.003230429815709638 0.0014443054317628786 9021/5594/6776/6774/6772/8651/4067/3717/2688/5617/6777/5595 12 Simian_virus_40 R-HSA-1433557 Signaling by SCF-KIT 18/2223 43/10654 0.0014427534404427543 0.0032540758270154222 0.0014548774189338698 4893/5290/3815/5578/4318/6776/6774/6772/6714/8651/8503/4067/3717/1111/2885/3845/6777/3265 18 Simian_virus_40 R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 8/2223 13/10654 0.0016573464128203429 0.003706931476674834 0.001657346412820343 207/2064/7316/10000/208/6233/7311/7314 8 Simian_virus_40 R-HSA-1679131 Trafficking and processing of endosomal TLR 8/2223 13/10654 0.0016573464128203429 0.003706931476674834 0.001657346412820343 54106/7184/7098/51311/1520/81622/51284/1514 8 Simian_virus_40 R-HSA-171007 p38MAPK events 8/2223 13/10654 0.0016573464128203429 0.003706931476674834 0.001657346412820343 4893/6714/1432/5603/3845/5600/3265/6300 8 Simian_virus_40 R-HSA-2995383 Initiation of Nuclear Envelope Reformation 8/2223 13/10654 0.0016573464128203429 0.003706931476674834 0.001657346412820343 4000/7443/7444/5520/2010/5518/7112/5515 8 Simian_virus_40 R-HSA-2995410 Nuclear Envelope Reassembly 8/2223 13/10654 0.0016573464128203429 0.003706931476674834 0.001657346412820343 4000/7443/7444/5520/2010/5518/7112/5515 8 Simian_virus_40 R-HSA-3299685 Detoxification of Reactive Oxygen Species 16/2223 37/10654 0.0017407074888042503 0.0038869042428873605 0.0017378111369094015 2876/2878/2936/7295/847/54205/2882/2877/493869/6648/5052/257202/5034/2880/7296/2950 16 Simian_virus_40 R-HSA-187687 Signalling to ERKs 15/2223 34/10654 0.0018898138049805752 0.004212840741335435 0.0018835353538012376 4893/5594/6714/1432/4914/5603/2885/1398/3845/5600/3265/1399/6300/7529/5595 15 Simian_virus_40 R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 26/2223 72/10654 0.002001785612097419 0.004445263539358885 0.0019874501666284137 5563/7531/4627/51807/7532/207/10971/51422/7533/2810/7277/53632/7534/4641/5571/7846/208/5867/9882/10383/60/84790/5564/5565/7280/7529 26 Simian_virus_40 R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 9/2223 16/10654 0.002007324668294698 0.004445263539358885 0.0019874501666284137 2648/3280/22938/8850/1387/2033/9794/3516/4851 9 Simian_virus_40 R-HSA-2559584 Formation of Senescence-Associated Heterochromatin Foci (SAHF) 9/2223 16/10654 0.002007324668294698 0.004445263539358885 0.0019874501666284137 3159/7290/5925/29855/25842/7157/8091/57634/23523 9 Simian_virus_40 R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 9/2223 16/10654 0.002007324668294698 0.004445263539358885 0.0019874501666284137 6885/7099/7316/3656/10454/7189/6233/7311/7314 9 Simian_virus_40 R-HSA-5654733 Negative regulation of FGFR4 signaling 14/2223 31/10654 0.0020296881681740164 0.004487383067033822 0.0020062815500896374 5594/7316/6714/2247/2264/6233/2885/2246/7311/5518/7314/5595/5515/5516 14 Simian_virus_40 R-HSA-3000178 ECM proteoglycans 27/2223 76/10654 0.002177804772191952 0.0048069309280947365 0.002149149446242058 1282/351/633/6678/375790/3911/1284/3339/1634/284217/1277/3912/3688/3915/1462/3910/3673/3908/1605/1463/2335/3909/3913/7040/3687/63827/5054 27 Simian_virus_40 R-HSA-9006115 Signaling by NTRK2 (TRKB) 12/2223 25/10654 0.0022323831047578718 0.004919307268612585 0.0021993922214363273 627/4893/5290/5335/2904/6714/2885/8851/3845/2549/3265/1020 12 Sindbis_virus R-HSA-73894 DNA Repair 104/379 334/10654 5.534366123032467e-72 5.484556827925175e-69 2.4467723912354063e-69 5982/672/404672/11284/5932/1017/8505/54107/6119/7311/7014/9557/6118/6047/7341/51548/2967/25/4683/2237/6612/472/6613/10401/5427/3150/3980/7507/55775/7706/7336/902/5888/2177/3978/3981/5887/580/1642/5983/6117/2965/5985/11073/2073/2072/5599/5591/2033/8450/165918/7334/54778/7316/10973/5981/10038/9978/142/2074/328/5423/10714/8914/2547/2068/7486/1111/10987/54386/2071/7157/10111/5424/57804/1022/4331/10721/5984/1069/5425/7329/641/5886/5111/56655/5426/51588/9100/1643/7508/2966/7314/7520/6233/7415/51720/8451/2067/675/8554/51426/7515/2968 104 Sindbis_virus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 61/379 84/10654 3.781435237791914e-71 1.8737011603258938e-68 8.358962104592654e-69 5982/404672/54107/6119/7311/9557/6118/7341/2967/6612/6613/10401/5427/3980/7507/7336/902/3978/5887/1642/5983/6117/2965/5985/2073/2072/8450/7334/54778/7316/5981/10038/9978/142/10714/2068/10987/2071/5424/57804/1022/4331/5984/1069/5425/7329/5886/5111/56655/5426/1643/7508/2966/7314/6233/8451/2067/8554/51426/7515/2968 61 Sindbis_virus R-HSA-5696398 Nucleotide Excision Repair 64/379 111/10654 1.0603879255645376e-64 3.5028147807815223e-62 1.5626769429372133e-62 5982/404672/54107/6119/7311/9557/6118/7341/2967/6612/6613/10401/5427/3150/3980/7507/7336/902/3978/5887/1642/5983/6117/2965/5985/2073/2072/2033/8450/7334/54778/7316/5981/10038/9978/142/2074/10714/2068/10987/2071/5424/57804/1022/4331/5984/1069/5425/7329/5886/5111/56655/5426/1643/7508/2966/7314/6233/8451/2067/8554/51426/7515/2968 64 Sindbis_virus R-HSA-5696400 Dual Incision in GG-NER 41/379 41/10654 4.5148146419632416e-61 1.1185453275463932e-58 4.990058288485689e-59 5982/404672/54107/6119/7311/9557/6118/2967/5427/7507/1642/5983/6117/2965/5985/2073/2072/8450/7316/5981/10038/9978/142/10714/2068/2071/5424/57804/5984/5425/5111/56655/5426/1643/2966/7314/6233/8451/2067/51426/2968 41 Sindbis_virus R-HSA-5696395 Formation of Incision Complex in GG-NER 42/379 43/10654 5.9910457432910186e-61 1.1874252663202799e-58 5.297345709857322e-59 404672/6119/7311/9557/6118/7341/2967/6612/6613/10401/7507/7336/902/5887/1642/6117/2965/2073/2072/8450/7334/54778/7316/10038/9978/142/2068/2071/1022/4331/1069/7329/5886/1643/7508/2966/7314/6233/8451/2067/8554/2968 42 Sindbis_virus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 47/379 79/10654 2.1878544945468336e-48 3.6136063401598535e-46 1.6121033117713511e-46 5982/404672/54107/6119/7311/6118/2967/5427/3150/3980/7507/902/3978/1642/5983/6117/2965/5985/2073/2072/2033/8450/7316/5981/9978/2074/10714/2068/10987/2071/5424/57804/1022/4331/5984/5425/5111/56655/5426/2966/7314/6233/8451/2067/51426/7515/2968 47 Sindbis_virus R-HSA-5693532 DNA Double-Strand Break Repair 62/379 166/10654 1.0960858321029601e-47 1.551744370877191e-45 6.922647360650275e-46 5982/672/5932/1017/54107/6119/7311/6118/6047/7341/51548/25/4683/2237/472/6613/5427/3980/55775/7336/5888/3981/580/5983/6117/5985/11073/2072/5599/5591/165918/7334/7316/5981/10038/142/10714/8914/2547/7486/1111/7157/10111/5424/57804/10721/5984/5425/7329/641/5111/56655/5426/51588/7314/7520/6233/51720/2067/675/51426/7515 62 Sindbis_virus R-HSA-6782135 Dual incision in TC-NER 43/379 66/10654 7.718397002898377e-47 9.561164287340365e-45 4.2654299226543666e-45 5982/404672/54107/6119/7311/6118/2967/5427/3150/7507/902/1642/5983/6117/2965/5985/2073/2072/2033/8450/7316/5981/9978/2074/10714/2068/2071/5424/57804/1022/4331/5984/5425/5111/56655/5426/2966/7314/6233/8451/2067/51426/2968 43 Sindbis_virus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 42/379 65/10654 1.5807939289797913e-45 1.740629759576637e-43 7.765303510777923e-44 5982/404672/54107/6119/7311/6118/2967/5427/3150/3980/902/3978/1642/5983/6117/2965/5985/2033/8450/7316/5981/9978/2074/10714/2068/2071/5424/57804/1022/4331/5984/5425/5111/56655/5426/2966/7314/6233/8451/51426/7515/2968 42 Sindbis_virus R-HSA-5693538 Homology Directed Repair 55/379 138/10654 4.1739019658140936e-44 4.136336848121766e-42 1.845304026991494e-42 5982/672/5932/1017/54107/6119/7311/6118/6047/7341/51548/25/4683/2237/472/6613/5427/3980/7336/5888/580/5983/6117/5985/11073/2072/165918/7334/7316/5981/10038/142/10714/8914/7486/1111/10111/5424/57804/10721/5984/5425/7329/641/5111/56655/5426/51588/7314/6233/51720/2067/675/51426/7515 55 Sindbis_virus R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 49/379 132/10654 1.5575657435563594e-37 1.403225138058502e-35 6.260072844915512e-36 5982/672/5932/1017/54107/6119/7311/6118/6047/7341/51548/25/4683/472/6613/5427/7336/5888/580/5983/6117/5985/11073/2072/165918/7334/7316/5981/10714/8914/7486/1111/10111/5424/57804/5984/5425/7329/641/5111/56655/5426/51588/7314/6233/51720/2067/675/51426 49 Sindbis_virus R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 25/379 25/10654 2.747743133804126e-37 2.2691778713332405e-35 1.0123264177173096e-35 5982/54107/6119/7311/6118/5427/3980/3978/5983/6117/5985/7316/5981/10714/5424/57804/5984/5425/5111/56655/5426/7314/6233/51426/7515 25 Sindbis_virus R-HSA-2990846 SUMOylation 54/379 188/10654 1.1900989174817492e-34 9.072215594033949e-33 4.0472999622861104e-33 672/115426/10155/9883/7150/9972/7341/1387/84733/6612/6613/10401/23636/1616/7155/8517/5914/2908/8021/7068/6117/29843/2033/5241/23512/648/10210/165918/142/7067/28996/7486/7428/3066/3065/7157/5970/4792/1107/9759/8535/1069/1786/7329/6045/641/5111/2099/51588/4927/7508/4193/8554/4869 54 Sindbis_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 53/379 182/10654 2.37377177750805e-34 1.68029130822177e-32 7.496121402657001e-33 672/115426/10155/9883/7150/9972/7341/1387/84733/6612/6613/10401/23636/1616/7155/8517/5914/2908/8021/7068/6117/2033/5241/23512/648/10210/165918/142/7067/28996/7486/7428/3066/3065/7157/5970/4792/1107/9759/8535/1069/1786/7329/6045/641/5111/2099/51588/4927/7508/4193/8554/4869 53 Sindbis_virus R-HSA-110373 Resolution of AP sites via the multiple-nucleotide patch replacement pathway 24/379 26/10654 2.505304721441935e-33 1.6551713192993049e-31 7.38405602109202e-32 5982/8505/54107/6119/6118/2237/5427/3978/5983/6117/5985/5981/10038/142/328/5423/10714/5424/57804/5984/5425/5111/56655/5426 24 Sindbis_virus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 25/379 30/10654 3.327560549866984e-32 2.0610078155738634e-30 9.194575203579826e-31 5982/54107/6119/7311/6118/5427/1642/5983/6117/5985/8450/7316/5981/9978/10714/5424/57804/5984/5425/5111/56655/5426/7314/6233/8451 25 Sindbis_virus R-HSA-5685942 HDR through Homologous Recombination (HRR) 34/379 67/10654 6.18832447452247e-32 3.607429149559863e-30 1.6093475413618807e-30 5982/672/5932/54107/6119/7311/6118/4683/472/5427/5888/580/5983/6117/5985/11073/7316/5981/10714/7486/1111/10111/5424/57804/5984/5425/641/5111/56655/5426/7314/6233/675/51426 34 Sindbis_virus R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 21/379 21/10654 2.17332513129097e-31 1.1965362250607507e-29 5.337991550539225e-30 5982/54107/6119/6118/2237/5427/3978/5983/6117/5985/5981/328/5423/10714/5424/57804/5984/5425/5111/56655/5426 21 Sindbis_virus R-HSA-73933 Resolution of Abasic Sites (AP sites) 27/379 39/10654 8.051114278856034e-31 4.1992917107085946e-29 1.8733894720883846e-29 5982/11284/8505/54107/6119/6118/2237/5427/3980/3978/5983/6117/5985/5981/10038/142/328/5423/10714/5424/57804/5984/5425/5111/56655/5426/7515 27 Sindbis_virus R-HSA-73893 DNA Damage Bypass 29/379 48/10654 2.07487434535287e-30 1.028100238122347e-28 4.5865643423589755e-29 5982/54107/6119/7311/6118/5427/7706/1642/5983/6117/5985/8450/7316/5981/9978/10714/5424/57804/5984/5425/5111/56655/5426/9100/7314/6233/7415/8451/51426 29 Sindbis_virus R-HSA-5656169 Termination of translesion DNA synthesis 24/379 32/10654 6.668043991662283e-29 3.1466817122558676e-27 1.4037987350867965e-27 5982/54107/6119/7311/6118/5427/7706/5983/6117/5985/7316/5981/10714/5424/57804/5984/5425/5111/56655/5426/9100/7314/6233/51426 24 Sindbis_virus R-HSA-3700989 Transcriptional Regulation by TP53 65/379 365/10654 2.8962878718293714e-28 1.3046460368104124e-26 5.820291417073377e-27 5982/672/2962/404672/5932/1025/6884/1017/2810/6119/7311/834/6118/6749/3725/2967/1387/4683/5562/472/1616/5300/902/2177/580/5983/4343/6117/2965/5985/11198/11073/2033/7316/5728/3276/1869/28996/2068/7486/1111/3066/3065/2071/7157/10111/1107/1022/54971/4331/1026/5984/207/641/5111/208/1643/1108/10498/2966/7314/6233/4193/4869/2968 65 Sindbis_virus R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 21/379 24/10654 3.9881742233567953e-28 1.7183828936289498e-26 7.666055715376906e-27 5982/54107/6119/6118/2237/5427/23649/3978/5983/6117/5985/5422/5981/10714/5424/57804/5984/5425/5111/56655/5426 21 Sindbis_virus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 25/379 39/10654 2.6275860376692235e-27 1.0849740680542502e-25 4.8402900693906747e-26 5982/54107/6119/7311/6118/5427/7706/5983/6117/5985/7316/5981/10714/5424/57804/5984/5425/5111/56655/5426/9100/7314/6233/7415/51426 25 Sindbis_virus R-HSA-180786 Extension of Telomeres 21/379 30/10654 2.3173231423223687e-24 9.18586893616587e-23 4.098003030633242e-23 5982/54107/6119/6118/2237/5427/23649/3978/5983/6117/5985/5422/5981/10714/5424/57804/5984/5425/5111/56655/5426 21 Sindbis_virus R-HSA-5693607 Processing of DNA double-strand break ends 33/379 98/10654 6.253827557392877e-24 2.383670426683208e-22 1.0634038761558736e-22 5982/672/5932/1017/6119/7311/6118/6047/7341/51548/4683/472/6613/7336/580/5983/6117/5985/11073/165918/7334/7316/8914/7486/1111/10111/5984/7329/641/51588/7314/6233/51720 33 Sindbis_virus R-HSA-69186 Lagging Strand Synthesis 17/379 20/10654 1.7017067191807546e-22 6.245893921141214e-21 2.7864203588924637e-21 5982/6119/6118/2237/23649/3978/5983/6117/5985/5422/5981/10714/5424/57804/5984/5425/5111 17 Sindbis_virus R-HSA-5633007 Regulation of TP53 Activity 39/379 160/10654 2.6669335640361134e-22 9.439039864142103e-21 4.2109477326886004e-21 5982/672/5932/6884/1017/6119/7311/6118/6749/4683/5562/472/1616/5300/580/5983/6117/5985/11198/11073/2033/7316/28996/7486/1111/3066/3065/7157/10111/1107/54971/5984/207/641/208/1108/7314/6233/4193 39 Sindbis_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 30/379 92/10654 2.194984575627429e-21 7.500792118782007e-20 3.346255977363049e-20 5982/672/5932/6884/1017/6119/7311/6118/6749/4683/5562/472/5300/580/5983/6117/5985/11198/11073/7316/28996/7486/1111/7157/10111/5984/641/7314/6233/4193 30 Sindbis_virus R-HSA-69242 S Phase 37/379 161/10654 2.9526776938130043e-020 9.75367864856229e-19 4.35131449614548e-19 5982/8454/1017/54107/6119/7311/6118/2237/5427/23649/902/3978/5698/5983/6117/5985/7316/5422/5981/9978/1869/10714/5424/57804/1022/4331/1026/5984/207/5425/5111/56655/5426/208/4609/7314/6233 37 Sindbis_virus R-HSA-73884 Base Excision Repair 29/379 92/10654 3.0618040788585875e-20 9.787896264996323e-19 4.366579671037714e-19 5982/11284/8505/54107/6119/7014/6118/2237/5427/3980/3978/5983/6117/5985/5981/10038/142/328/5423/10714/54386/5424/57804/5984/5425/5111/56655/5426/7515 29 Sindbis_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 22/379 47/10654 4.7979575254084923e-20 1.4858674711499425e-18 6.62875710747226e-19 10014/8454/22938/8850/7311/3091/1387/8841/2033/7316/9978/9734/3066/3065/4851/7088/9759/1024/3280/4609/7314/6233 22 Sindbis_virus R-HSA-5685938 HDR through Single Strand Annealing (SSA) 20/379 37/10654 5.874442017811139e-20 1.764112739288133e-18 7.870065861182386e-19 5982/672/5932/6119/6118/25/4683/472/5888/580/5983/6117/5985/11073/2072/7486/10111/5984/641/2067 20 Sindbis_virus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 23/379 54/10654 9.701981880092949e-20 2.8278423656388565e-18 1.2615580153681234e-18 404672/7311/2967/3150/7507/902/1642/2965/2033/8450/7316/9978/2074/2068/10987/2071/1022/4331/2966/7314/6233/8451/2968 23 Sindbis_virus R-HSA-5655862 Translesion synthesis by POLK 14/379 17/10654 2.535473774055799e-18 7.179012885969418e-17 3.2027037145967987e-017 5982/6119/7311/6118/5983/6117/5985/7316/5981/5984/5111/7314/6233/51426 14 Sindbis_virus R-HSA-69306 DNA Replication 31/379 127/10654 5.9626301940122786e-18 1.6413795895183801e-16 7.322528308436131e-17 5982/8454/1017/54107/6119/7311/6118/2237/5427/23649/3978/5698/5983/6117/5985/7316/5422/5981/9978/1869/10714/5424/57804/5984/5425/5111/56655/5426/7314/6233/29935 31 Sindbis_virus R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 19/379 39/10654 6.817183096381521e-18 1.825899580679483e-16 8.145709531949471e-17 5982/672/5932/6119/6118/4683/472/5888/580/5983/6117/5985/11073/7486/1111/10111/5984/641/675 19 Sindbis_virus R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 19/379 42/10654 4.0062554300444627e-17 1.0322985991096333e-15 4.605294084933305e-16 5982/672/5932/6119/6118/4683/472/5888/580/5983/6117/5985/11073/7486/1111/10111/5984/641/675 19 Sindbis_virus R-HSA-110320 Translesion Synthesis by POLH 14/379 19/10654 4.0625272820661654e-17 1.0322985991096333e-15 4.605294084933305e-16 5982/6119/7311/6118/5983/6117/5985/7316/5981/5984/5111/7314/6233/7415 14 Sindbis_virus R-HSA-69190 DNA strand elongation 17/379 32/10654 5.706224836184524e-17 1.4137172031647158e-15 6.306880082098685e-16 5982/6119/6118/2237/23649/3978/5983/6117/5985/5422/5981/10714/5424/57804/5984/5425/5111 17 Sindbis_virus R-HSA-110312 Translesion synthesis by REV1 13/379 16/10654 6.072212691673008e-17 1.4676982384019393e-15 6.547700463421471e-16 5982/6119/7311/6118/5983/6117/5985/7316/5981/5984/5111/7314/6233 13 Sindbis_virus R-HSA-5663202 Diseases of signal transduction 51/379 377/10654 7.459649591611152e-17 1.7553512385279053e-15 7.830979023652028e-16 4089/5295/10014/8454/2962/4000/22938/409/2308/27044/8850/7311/1387/2931/1956/4088/8841/5698/2335/3845/2033/7316/1499/5728/673/9978/9734/842/816/3066/3065/4851/9759/8658/817/1026/207/1024/4087/942/5245/2099/6934/5594/208/3280/4609/7314/6233/7415/4193 51 Sindbis_virus R-HSA-69239 Synthesis of DNA 29/379 119/10654 7.616559359909175e-17 1.7553512385279053e-15 7.830979023652028e-16 5982/8454/1017/54107/6119/7311/6118/2237/5427/23649/3978/5698/5983/6117/5985/7316/5422/5981/9978/10714/5424/57804/5984/5425/5111/56655/5426/7314/6233 29 Sindbis_virus R-HSA-6807070 PTEN Regulation 31/379 140/10654 1.2003700938364266e-16 2.703560824981588e-15 1.2061134914145912e-15 81847/10014/57504/7311/3725/84733/8841/5698/4343/23512/648/7316/5728/6615/2146/3066/3065/5978/7157/1107/8535/8658/10273/207/6045/5594/208/1108/7314/6233/11060 31 Sindbis_virus R-HSA-3899300 SUMOylation of transcription cofactors 19/379 45/10654 1.9822481994427468e-16 4.3653510347728045e-15 1.947471915241997e-15 115426/10155/7341/1387/84733/6612/6613/10401/1616/2033/648/10210/28996/8535/7329/6045/51588/8554/4869 19 Sindbis_virus R-HSA-5656121 Translesion synthesis by POLI 13/379 17/10654 2.4982874963042304e-16 5.382180236603245e-15 2.401100110864478e-15 5982/6119/7311/6118/5983/6117/5985/7316/5981/5984/5111/7314/6233 13 Sindbis_virus R-HSA-1980143 Signaling by NOTCH1 23/379 73/10654 2.731102403732191e-16 5.758558472550215e-15 2.569010099815275e-15 10014/8454/22938/409/8850/7311/3091/1387/8841/2033/7316/9978/9734/3066/3065/4851/7088/9759/1024/3280/4609/7314/6233 23 Sindbis_virus R-HSA-174411 Polymerase switching on the C-strand of the telomere 12/379 14/10654 2.956289804777752e-16 5.8593663930695046e-15 2.613982564224539e-15 5982/23649/5983/5985/5422/5981/10714/5424/57804/5984/5425/5111 12 Sindbis_virus R-HSA-69091 Polymerase switching 12/379 14/10654 2.956289804777752e-16 5.8593663930695046e-15 2.613982564224539e-15 5982/23649/5983/5985/5422/5981/10714/5424/57804/5984/5425/5111 12 Sindbis_virus R-HSA-69109 Leading Strand Synthesis 12/379 14/10654 2.956289804777752e-16 5.8593663930695046e-15 2.613982564224539e-15 5982/23649/5983/5985/5422/5981/10714/5424/57804/5984/5425/5111 12 Sindbis_virus R-HSA-453279 Mitotic G1-G1/S phases 31/379 149/10654 7.816517460418974e-16 1.518856628093177e-14 6.775928448660412e-15 8454/1017/54107/6119/7311/6118/25/5427/4067/23649/4605/902/5698/6117/7316/5422/1869/3065/1022/4331/1026/207/5111/56655/5426/208/4609/7314/6233/6241/29935 31 Sindbis_virus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 23/379 77/10654 1.0255220149162707e-15 1.9544083015038928e-14 8.719013082284083e-15 672/9883/9972/7341/84733/6612/6613/23636/8021/6117/648/165918/142/7486/8535/1069/7329/6045/641/51588/4927/7508/8554 23 Sindbis_virus R-HSA-162587 HIV Life Cycle 31/379 152/10654 1.412908795148214e-15 2.6263354371396177e-14 1.1716616746493595e-14 2962/404672/1025/6884/7311/9883/9972/6749/2967/2237/23636/8021/902/3978/3981/8815/2965/11198/7316/3159/2547/2068/2071/1022/4331/4927/2966/7314/7520/6233/2968 31 Sindbis_virus R-HSA-69183 Processive synthesis on the lagging strand 12/379 15/10654 1.4311010454645747e-15 2.6263354371396177e-14 1.1716616746493595e-14 6119/6118/2237/23649/3978/6117/5422/10714/5424/57804/5425/5111 12 Sindbis_virus R-HSA-69473 G2/M DNA damage checkpoint 25/379 95/10654 1.5602858228284692e-15 2.8113513644054784e-14 1.2542010441874777e-14 5982/672/5932/2810/6119/6118/7341/4683/472/7336/580/5983/6117/5985/11073/165918/7334/7486/1111/7157/10111/5984/641/51588/51720 25 Sindbis_virus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 21/379 65/10654 3.133634455032328e-15 5.5454138302447093e-14 2.4739219381834167e-14 672/2962/404672/1025/6749/3725/2967/472/902/2177/2965/11198/2068/1111/2071/7157/1022/4331/1643/2966/2968 21 Sindbis_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 20/379 58/10654 3.4340818855876312e-15 5.578975653471053e-14 2.4888945503827527e-14 10014/8454/22938/8850/7311/1387/8841/2033/7316/9978/9734/3066/3065/4851/9759/1024/3280/4609/7314/6233 20 Sindbis_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 20/379 58/10654 3.4340818855876312e-15 5.578975653471053e-14 2.4888945503827527e-14 10014/8454/22938/8850/7311/1387/8841/2033/7316/9978/9734/3066/3065/4851/9759/1024/3280/4609/7314/6233 20 Sindbis_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 20/379 58/10654 3.4340818855876312e-15 5.578975653471053e-14 2.4888945503827527e-14 10014/8454/22938/8850/7311/1387/8841/2033/7316/9978/9734/3066/3065/4851/9759/1024/3280/4609/7314/6233 20 Sindbis_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 20/379 58/10654 3.4340818855876312e-15 5.578975653471053e-14 2.4888945503827527e-14 10014/8454/22938/8850/7311/1387/8841/2033/7316/9978/9734/3066/3065/4851/9759/1024/3280/4609/7314/6233 20 Sindbis_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 20/379 58/10654 3.4340818855876312e-15 5.578975653471053e-14 2.4888945503827527e-14 10014/8454/22938/8850/7311/1387/8841/2033/7316/9978/9734/3066/3065/4851/9759/1024/3280/4609/7314/6233 20 Sindbis_virus R-HSA-1257604 PIP3 activates AKT signaling 40/379 264/10654 4.428038163223147e-15 7.077719064119579e-14 3.1575144797176944e-14 81847/5295/10014/57504/2308/7311/3725/84733/2931/1956/8841/5698/4343/23512/648/7316/5728/842/6615/2146/3066/3065/5978/7157/1107/8535/8658/1026/10273/207/942/6045/2099/5594/208/1108/7314/6233/4193/11060 40 Sindbis_virus R-HSA-157579 Telomere Maintenance 23/379 82/10654 4.7468824116502945e-15 7.46692138086578e-14 3.3311455520352945e-14 5982/54107/6119/7014/6118/2237/5427/23649/3978/5983/6117/5985/5422/5981/10714/54386/5424/57804/5984/5425/5111/56655/5426 23 Sindbis_virus R-HSA-69206 G1/S Transition 28/379 131/10654 9.941622120304727e-15 1.5393980501909352e-13 6.867567912052609e-14 8454/1017/54107/6119/7311/6118/5427/23649/902/5698/6117/7316/5422/1869/3065/1022/4331/1026/207/5111/56655/5426/208/4609/7314/6233/6241/29935 28 Sindbis_virus R-HSA-8878159 Transcriptional regulation by RUNX3 24/379 96/10654 2.050155263490915e-14 3.125698255568457e-13 1.3944375881233756e-13 4089/22938/8850/7311/1387/4088/5698/6696/3845/2033/7316/1499/4851/7157/9759/1026/10413/3676/6934/3280/4609/7314/6233/4193 24 Sindbis_virus R-HSA-8953897 Cellular responses to external stimuli 55/379 493/10654 2.0990058450655037e-14 3.1516890794847184e-13 1.4060326234888542e-13 3306/1017/6119/7311/3303/7014/3091/6118/9883/9972/3725/1387/84733/4683/472/23636/23411/2908/8021/5698/4343/6117/4520/4790/5599/2033/5241/23512/648/7316/3159/9978/1869/2113/816/7428/2146/54386/9531/81027/7157/10111/5970/8535/817/1026/6045/6667/768/5594/4927/7314/6233/7415/4193 55 Sindbis_virus R-HSA-2262752 Cellular responses to stress 54/379 479/10654 2.4068508486824656e-14 3.5599838672303333e-13 1.5881812355799458e-13 3306/1017/6119/7311/3303/7014/3091/6118/9883/9972/3725/1387/84733/4683/472/23636/23411/2908/8021/5698/4343/6117/4790/5599/2033/5241/23512/648/7316/3159/9978/1869/2113/816/7428/2146/54386/9531/81027/7157/10111/5970/8535/817/1026/6045/6667/768/5594/4927/7314/6233/7415/4193 54 Sindbis_virus R-HSA-69481 G2/M Checkpoints 31/379 168/10654 2.613630833106084e-14 3.808982581776661e-13 1.699264628335225e-13 5982/672/5932/1017/2810/6119/7311/6118/7341/4683/472/7336/5698/580/5983/6117/5985/11073/165918/7334/7316/7486/1111/7157/10111/5984/641/51588/7314/6233/51720 31 Sindbis_virus R-HSA-9006925 Intracellular signaling by second messengers 42/379 305/10654 2.6983072385304324e-14 3.875394888961824e-13 1.7288925098135496e-13 81847/5295/10014/57504/2308/7311/3725/84733/2931/1956/8841/5698/4343/23512/648/7316/5728/842/6615/816/2146/3066/3065/5978/7157/1107/8535/8658/817/1026/10273/207/942/6045/2099/5594/208/1108/7314/6233/4193/11060 42 Sindbis_virus R-HSA-174414 Processive synthesis on the C-strand of the telomere 10/379 11/10654 3.0802337059491163e-14 4.36073086085082e-13 1.9454107616520735e-13 6119/6118/2237/3978/6117/10714/5424/57804/5425/5111 10 Sindbis_virus R-HSA-69166 Removal of the Flap Intermediate 11/379 14/10654 3.3125582163791884e-14 4.623584778072924e-13 2.0626752422227713e-13 6119/6118/2237/23649/6117/5422/10714/5424/57804/5425/5111 11 Sindbis_virus R-HSA-5696394 DNA Damage Recognition in GG-NER 16/379 38/10654 5.234135312426039e-14 7.204205686964173e-13 3.213942735700199e-13 7311/5887/1642/8450/7316/10038/9978/142/10987/1069/5886/1643/7508/7314/6233/8451 16 Sindbis_virus R-HSA-5663205 Infectious disease 47/379 383/10654 5.909030806395936e-14 8.021711683751195e-13 3.5786487940681955e-13 2962/404672/1025/6884/7311/3303/9883/9972/6749/2967/6202/2237/6123/23636/6189/8021/902/6194/6134/3978/5698/3981/8815/2965/11198/7316/1499/3159/6147/9978/6143/2547/9045/2068/2071/1022/4331/6157/200916/4927/11224/2966/7314/7520/6233/4869/2968 47 Sindbis_virus R-HSA-73886 Chromosome Maintenance 25/379 110/10654 6.251565105569777e-14 8.372028404891418e-13 3.7349322110089713e-13 5982/54107/6119/7014/6118/2237/5427/23649/3978/5983/6117/5985/5422/5981/10714/1058/54386/5424/57804/5984/5425/5111/56655/5426/4869 25 Sindbis_virus R-HSA-73762 RNA Polymerase I Transcription Initiation 17/379 47/10654 1.6941345423215028e-13 2.2385164419208123e-12 9.986477302105703e-13 404672/57504/8850/2967/902/2965/2074/2068/3066/3065/2071/1107/1022/4331/1108/2966/2968 17 Sindbis_virus R-HSA-4090294 SUMOylation of intracellular receptors 14/379 30/10654 3.5527521806612867e-13 4.632601856625441e-12 2.0666979444290033e-12 7341/6612/6613/10401/5914/2908/7068/5241/7067/9759/7329/2099/51588/8554 14 Sindbis_virus R-HSA-174437 Removal of the Flap Intermediate from the C-strand 9/379 10/10654 8.058229641347512e-13 1.0238084069968441e-11 4.567417610480371e-12 6119/6118/2237/6117/10714/5424/57804/5425/5111 9 Sindbis_virus R-HSA-5685939 HDR through MMEJ (alt-NHEJ) 9/379 10/10654 8.058229641347512e-13 1.0238084069968441e-11 4.567417610480371e-12 5932/4683/2237/3980/10038/142/10111/10721/7515 9 Sindbis_virus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 14/379 32/10654 1.0792465966941213e-12 1.3538397181314862e-11 6.0397544385280604e-12 4089/22938/1025/7311/4088/54778/7316/3065/1024/4087/6667/4609/7314/6233 14 Sindbis_virus R-HSA-162906 HIV Infection 34/379 233/10654 1.6993822927490918e-12 2.105109815142937e-11 9.391323196771297e-12 2962/404672/1025/6884/7311/9883/9972/6749/2967/2237/23636/8021/902/3978/5698/3981/8815/2965/11198/7316/3159/9978/2547/2068/2071/1022/4331/4927/2966/7314/7520/6233/4869/2968 34 Sindbis_virus R-HSA-8943724 Regulation of PTEN gene transcription 18/379 61/10654 1.8038439191274583e-12 2.2069250911793965e-11 9.845541858785347e-12 10014/57504/3725/84733/8841/23512/648/6615/2146/3066/3065/5978/7157/1107/8535/6045/5594/1108 18 Sindbis_virus R-HSA-157118 Signaling by NOTCH 34/379 235/10654 2.1785194857917226e-12 2.6328205005117038e-11 1.1745547933665258e-11 10014/8454/22938/409/8850/7311/3091/3725/51548/1387/1956/4088/8841/5698/4343/2033/7316/9978/1869/9734/3002/3066/3065/4851/7157/7088/9759/207/1024/3280/4609/7314/6233/11060 34 Sindbis_virus R-HSA-4551638 SUMOylation of chromatin organization proteins 19/379 71/10654 3.0122244968971365e-12 3.596523465572364e-11 1.604482293845019e-11 9883/9972/7341/84733/6612/6613/23636/8021/23512/648/3066/3065/1107/9759/8535/7329/6045/4927/8554 19 Sindbis_virus R-HSA-4755510 SUMOylation of immune response proteins 9/379 11/10654 4.293415785973398e-12 5.065208385594806e-11 2.2596925189333674e-11 7341/6612/10401/8517/10210/5970/4792/7329/51588 9 Sindbis_virus R-HSA-9614085 FOXO-mediated transcription 18/379 65/10654 6.008324173540519e-12 7.00499912468077e-11 3.1250726351542016e-11 4089/2308/8850/2810/1387/4287/23411/4088/2908/10628/2033/3066/3065/1026/207/4087/208/23410 18 Sindbis_virus R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 20/379 84/10654 8.530289196785978e-12 9.829670458156865e-11 4.385215988555827e-11 7124/9968/1387/23054/10001/8841/688/9439/4790/2033/9967/9440/5469/9443/9282/1050/5970/1024/10498/9862 20 Sindbis_virus R-HSA-5693565 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 19/379 76/10654 1.1287096653901253e-11 1.2856911245995567e-10 5.735729697082308e-11 672/7311/7341/25/4683/472/7336/580/5599/165918/7334/7316/7157/10111/7329/51588/7314/6233/51720 19 Sindbis_virus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 15/379 44/10654 1.2604694469612195e-11 1.419460479475646e-10 6.332502006264501e-11 4089/22938/1025/7311/4088/54778/7316/142/3065/1024/4087/6667/4609/7314/6233 15 Sindbis_virus R-HSA-5693606 DNA Double Strand Break Response 19/379 77/10654 1.4502773195564302e-11 1.6148593524499127e-10 7.204216134993503e-11 672/7311/7341/25/4683/472/7336/580/5599/165918/7334/7316/7157/10111/7329/51588/7314/6233/51720 19 Sindbis_virus R-HSA-2559583 Cellular Senescence 29/379 195/10654 4.9185508762134785e-11 5.415871020363952e-10 2.4161302549820596e-10 1017/7311/7014/3725/84733/4683/472/4343/4790/5599/23512/648/7316/3159/1869/2113/2146/54386/7157/10111/5970/8535/1026/6045/6667/5594/7314/6233/4193 29 Sindbis_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 18/379 73/10654 5.107889448555224e-11 5.562547740129921e-10 2.481565723994441e-10 4089/22938/1025/7311/4088/54778/7316/142/3065/9040/10273/1024/4087/6667/4738/4609/7314/6233 18 Sindbis_virus R-HSA-69620 Cell Cycle Checkpoints 36/379 293/10654 6.155736653675252e-11 6.630798938904538e-10 2.958134318699778e-10 5982/701/672/5932/1017/2810/6119/7311/9184/6118/7341/4683/472/7336/5698/580/5983/6117/5985/11073/165918/7334/7316/1058/7486/1111/7157/10111/1026/5984/641/51588/7314/6233/51720/4193 36 Sindbis_virus R-HSA-5688426 Deubiquitination 36/379 297/10654 9.09052551840174e-11 9.686785794339918e-10 4.321472232856515e-10 4089/81847/672/409/8850/7311/3091/9097/4287/4088/7706/8517/5698/5887/580/2033/7316/5728/1540/5423/8473/7157/4792/8658/4087/4738/5886/2099/9100/1643/4609/7314/6233/7415/51720/4193 36 Sindbis_virus R-HSA-162599 Late Phase of HIV Life Cycle 24/379 139/10654 1.0209599599804314e-10 1.0763524684474547e-9 4.80182735937045e-10 2962/404672/1025/6884/7311/9883/9972/6749/2967/23636/8021/902/2965/11198/7316/2068/2071/1022/4331/4927/2966/7314/6233/2968 24 Sindbis_virus R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 9/379 14/10654 1.420779610207159e-10 1.4666589517867652e-9 6.543063994375074e-10 6119/6118/3978/6117/10714/5424/57804/5425/5111 9 Sindbis_virus R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 9/379 14/10654 1.420779610207159e-10 1.4666589517867652e-9 6.543063994375074e-10 6119/6118/3978/6117/10714/5424/57804/5425/5111 9 Sindbis_virus R-HSA-3371556 Cellular response to heat stress 19/379 89/10654 2.1861586043174674e-10 2.233487811215062e-9 9.964043557388349e-10 3306/6119/3303/6118/9883/9972/1387/472/23636/23411/8021/6117/2033/816/9531/817/5594/4927/7415 19 Sindbis_virus R-HSA-8878166 Transcriptional regulation by RUNX2 22/379 121/10654 2.2218940319476105e-10 2.246833658836818e-9 1.0023582099011777e-9 4089/8454/7311/25/3958/8841/2908/10432/5698/7316/9978/9759/1026/10273/207/10413/2099/5594/208/3280/7314/6233 22 Sindbis_virus R-HSA-4615885 SUMOylation of DNA replication proteins 14/379 45/10654 2.504134801426236e-10 2.5066642305185857e-9 1.1182739145125136e-9 9883/7150/9972/7341/6612/6613/10401/23636/7155/8021/7329/5111/51588/4927 14 Sindbis_virus R-HSA-5358508 Mismatch Repair 9/379 15/10654 3.4409717514140173e-10 3.3527427720919347e-9 1.4957267664545249e-9 6119/6118/3978/6117/10714/5424/57804/5425/5111 9 Sindbis_virus R-HSA-167169 HIV Transcription Elongation 14/379 46/10654 3.484687240418459e-10 3.3527427720919347e-9 1.4957267664545249e-9 2962/404672/1025/6749/2967/902/2965/11198/2068/2071/1022/4331/2966/2968 14 Sindbis_virus R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 14/379 46/10654 3.484687240418459e-10 3.3527427720919347e-9 1.4957267664545249e-9 2962/404672/1025/6749/2967/902/2965/11198/2068/2071/1022/4331/2966/2968 14 Sindbis_virus R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 14/379 46/10654 3.484687240418459e-10 3.3527427720919347e-9 1.4957267664545249e-9 2962/404672/1025/6749/2967/902/2965/11198/2068/2071/1022/4331/2966/2968 14 Sindbis_virus R-HSA-212165 Epigenetic regulation of gene expression 24/379 149/10654 4.5310594072455615e-10 4.31757680055803e-9 1.9261588573311094e-9 404672/57504/8850/2967/23411/902/2965/2033/23512/2074/2068/2146/3066/3065/2071/29128/1107/1022/4331/1786/1108/2966/9188/2968 24 Sindbis_virus R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 14/379 48/10654 6.566137577852541e-10 6.197183180620826e-9 2.764689506464228e-9 2962/404672/1025/6749/2967/902/2965/11198/2068/2071/1022/4331/2966/2968 14 Sindbis_virus R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 11/379 27/10654 7.810368127519754e-10 7.233714779786987e-9 3.227107342408556e-9 2962/404672/2967/902/2965/2068/2071/1022/4331/2966/2968 11 Sindbis_virus R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 11/379 27/10654 7.810368127519754e-10 7.233714779786987e-9 3.227107342408556e-9 2962/404672/2967/902/2965/2068/2071/1022/4331/2966/2968 11 Sindbis_virus R-HSA-5689877 Josephin domain DUBs 8/379 12/10654 1.0418937959329223e-9 9.560340294162277e-9 4.26506232253243e-9 7311/4287/5887/7316/5886/7314/6233/7415 8 Sindbis_virus R-HSA-5693571 Nonhomologous End-Joining (NHEJ) 16/379 69/10654 1.6390087923778774e-9 1.4901446910518135e-8 6.647838655709401e-9 672/7341/4683/472/55775/7336/3981/580/5591/165918/7334/2547/10111/51588/7520/51720 16 Sindbis_virus R-HSA-72086 mRNA Capping 11/379 29/10654 1.9435734865118317e-9 1.7509830228483867e-8 7.811491524736549e-9 2962/404672/2967/902/2965/2068/2071/1022/4331/2966/2968 11 Sindbis_virus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 10/379 23/10654 2.1825395273960672e-9 1.948555560044597e-8 8.69290281181933e-9 4089/7311/4088/54778/7316/142/3065/4087/7314/6233 10 Sindbis_virus R-HSA-209560 NF-kB is activated and signals survival 8/379 13/10654 2.6251173582992215e-9 2.322760091137972e-8 1.0362305361707452e-8 7311/4790/7316/5970/4792/8878/7314/6233 8 Sindbis_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 14/379 55/10654 4.722310231506874e-9 4.141424282675497e-8 1.8475736350562526e-8 7311/834/596/841/8517/10628/4790/7334/7316/1540/842/5970/7314/6233 14 Sindbis_virus R-HSA-69002 DNA Replication Pre-Initiation 17/379 85/10654 5.711692568385528e-9 4.965164329184262e-8 2.215060829844803e-8 1017/54107/6119/7311/6118/5427/23649/5698/6117/7316/5422/1869/56655/5426/7314/6233/29935 17 Sindbis_virus R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 7/379 10/10654 7.469377239550387e-9 6.436654647299507e-8 2.8715226001017507e-8 2308/8850/1387/23411/10628/2033/23410 7 Sindbis_virus R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 10/379 26/10654 9.207469761985815e-9 7.866036667351673e-8 3.509199001845774e-8 672/5932/4683/472/5888/580/7486/10111/641/675 10 Sindbis_virus R-HSA-113418 Formation of the Early Elongation Complex 11/379 33/10654 9.561799746602273e-9 7.896452957402376e-8 3.522768327695575e-8 2962/404672/2967/902/2965/2068/2071/1022/4331/2966/2968 11 Sindbis_virus R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 11/379 33/10654 9.561799746602273e-9 7.896452957402376e-8 3.522768327695575e-8 2962/404672/2967/902/2965/2068/2071/1022/4331/2966/2968 11 Sindbis_virus R-HSA-2559585 Oncogene Induced Senescence 11/379 33/10654 9.561799746602273e-9 7.896452957402376e-8 3.522768327695575e-8 7311/4343/7316/1869/2113/7157/6667/5594/7314/6233/4193 11 Sindbis_virus R-HSA-68962 Activation of the pre-replicative complex 11/379 33/10654 9.561799746602273e-9 7.896452957402376e-8 3.522768327695575e-8 1017/54107/6119/6118/5427/23649/6117/5422/56655/5426/29935 11 Sindbis_virus R-HSA-3232118 SUMOylation of transcription factors 9/379 20/10654 9.853892381252083e-9 8.070419297372573e-8 3.6003782515231626e-8 7341/6612/6613/10401/7157/7329/51588/4193/8554 9 Sindbis_virus R-HSA-9006936 Signaling by TGF-beta family members 18/379 102/10654 1.6328459336124534e-8 1.3263527214835584e-7 5.917129353901903e-8 4089/22938/1025/7311/4088/54778/7316/142/3065/9040/10273/1024/4087/6667/4738/4609/7314/6233 18 Sindbis_virus R-HSA-109581 Apoptosis 24/379 178/10654 1.750655181964925e-8 1.410487223843285e-7 6.292470487165327e-8 4000/8428/2810/7311/840/596/841/836/5698/5599/7316/1499/1869/4137/5747/842/3002/7157/207/5594/208/7314/6233/3146 24 Sindbis_virus R-HSA-112382 Formation of RNA Pol II elongation complex 14/379 61/10654 2.0101086543228712e-8 1.5936141411471723e-7 7.109436924762998e-8 2962/404672/1025/6749/2967/902/2965/11198/2068/2071/1022/4331/2966/2968 14 Sindbis_virus R-HSA-75955 RNA Polymerase II Transcription Elongation 14/379 61/10654 2.0101086543228712e-8 1.5936141411471723e-7 7.109436924762998e-8 2962/404672/1025/6749/2967/902/2965/11198/2068/2071/1022/4331/2966/2968 14 Sindbis_virus R-HSA-350054 Notch-HLH transcription pathway 10/379 28/10654 2.1341115289823843e-8 1.6784956549377325e-7 7.488110628008367e-8 10014/22938/8850/1387/8841/9734/3066/3065/4851/9759 10 Sindbis_virus R-HSA-193639 p75NTR signals via NF-kB 8/379 16/10654 2.3890851409793402e-8 1.864238877724824e-7 8.316748936687302e-8 7311/4790/7316/5970/4792/8878/7314/6233 8 Sindbis_virus R-HSA-5357801 Programmed Cell Death 24/379 181/10654 2.4379900234704897e-8 1.8875375884837933e-7 8.420689225802679e-8 4000/8428/2810/7311/840/596/841/836/5698/5599/7316/1499/1869/4137/5747/842/3002/7157/207/5594/208/7314/6233/3146 24 Sindbis_virus R-HSA-8878171 Transcriptional regulation by RUNX1 28/379 239/10654 2.599250088705351e-8 1.9675957027983975e-7 8.777844762603718e-8 8850/7311/25/1387/84733/3958/4773/902/5698/4343/2033/648/6597/7316/3276/6886/4602/6929/28996/3065/1022/4331/8535/6045/10413/2099/7314/6233 28 Sindbis_virus R-HSA-69231 Cyclin D associated events in G1 12/379 44/10654 2.60095900168103e-8 1.9675957027983975e-7 8.777844762603718e-8 8454/7311/25/4067/902/7316/1869/1022/4331/1026/7314/6233 12 Sindbis_virus R-HSA-69236 G1 Phase 12/379 44/10654 2.60095900168103e-8 1.9675957027983975e-7 8.777844762603718e-8 8454/7311/25/4067/902/7316/1869/1022/4331/1026/7314/6233 12 Sindbis_virus R-HSA-6804757 Regulation of TP53 Degradation 11/379 36/10654 2.695862854358893e-8 2.023939461113381e-7 9.029205732302513e-8 1017/7311/472/1616/7316/7157/207/208/7314/6233/4193 11 Sindbis_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 13/379 53/10654 2.7515851665497698e-8 2.0502412782337006e-7 9.146543489916132e-8 2810/840/596/841/836/5599/1869/842/3002/7157/207/5594/208 13 Sindbis_virus R-HSA-167172 Transcription of the HIV genome 15/379 73/10654 3.104421760206811e-8 2.2958820629589178e-7 1.0242397009323335e-7 2962/404672/1025/6884/6749/2967/902/2965/11198/2068/2071/1022/4331/2966/2968 15 Sindbis_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 14/379 63/10654 3.1286089300515714e-8 2.2966307034674869e-7 1.0245736846952513e-7 7311/1387/8517/4790/5591/2033/7316/1499/2547/5970/4792/7314/7520/6233 14 Sindbis_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 11/379 37/10654 3.715297243954632e-8 2.707249682911059e-7 1.207759165991444e-7 1017/7311/472/1616/7316/7157/207/208/7314/6233/4193 11 Sindbis_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 16/379 85/10654 4.0034446181590665e-8 2.8542544004285146e-7 1.2733409614742963e-7 8454/7311/3725/8517/4790/5599/7334/7316/57162/5970/4792/51231/5594/7314/6233/3146 16 Sindbis_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 16/379 85/10654 4.0034446181590665e-8 2.8542544004285146e-7 1.2733409614742963e-7 8454/7311/3725/8517/4790/5599/7334/7316/57162/5970/4792/51231/5594/7314/6233/3146 16 Sindbis_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 16/379 85/10654 4.0034446181590665e-8 2.8542544004285146e-7 1.2733409614742963e-7 8454/7311/3725/8517/4790/5599/7334/7316/57162/5970/4792/51231/5594/7314/6233/3146 16 Sindbis_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 20/379 134/10654 4.991865010923945e-8 3.533527304161164e-7 1.5763784245022986e-7 5295/8454/7311/3725/4067/4773/8517/5698/4790/3845/5599/7334/7316/4772/5970/4792/997/5594/7314/6233 20 Sindbis_virus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 11/379 38/10654 5.0638778682565886e-8 3.5590801187533894e-7 1.5877780549964668e-7 9883/9972/7341/23636/8021/7428/7329/51588/4927/4193/8554 11 Sindbis_virus R-HSA-167161 HIV Transcription Initiation 12/379 47/10654 5.850132798691113e-8 3.917217299664117e-7 1.747550338158085e-7 2962/404672/6884/2967/902/2965/2068/2071/1022/4331/2966/2968 12 Sindbis_virus R-HSA-167162 RNA Polymerase II HIV Promoter Escape 12/379 47/10654 5.850132798691113e-8 3.917217299664117e-7 1.747550338158085e-7 2962/404672/6884/2967/902/2965/2068/2071/1022/4331/2966/2968 12 Sindbis_virus R-HSA-4570464 SUMOylation of RNA binding proteins 12/379 47/10654 5.850132798691113e-8 3.917217299664117e-7 1.747550338158085e-7 9883/9972/7341/84733/6613/23636/8021/648/8535/7329/6045/4927 12 Sindbis_virus R-HSA-73776 RNA Polymerase II Promoter Escape 12/379 47/10654 5.850132798691113e-8 3.917217299664117e-7 1.747550338158085e-7 2962/404672/6884/2967/902/2965/2068/2071/1022/4331/2966/2968 12 Sindbis_virus R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 12/379 47/10654 5.850132798691113e-8 3.917217299664117e-7 1.747550338158085e-7 2962/404672/6884/2967/902/2965/2068/2071/1022/4331/2966/2968 12 Sindbis_virus R-HSA-75953 RNA Polymerase II Transcription Initiation 12/379 47/10654 5.850132798691113e-8 3.917217299664117e-7 1.747550338158085e-7 2962/404672/6884/2967/902/2965/2068/2071/1022/4331/2966/2968 12 Sindbis_virus R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 12/379 47/10654 5.850132798691113e-8 3.917217299664117e-7 1.747550338158085e-7 2962/404672/6884/2967/902/2965/2068/2071/1022/4331/2966/2968 12 Sindbis_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 15/379 78/10654 7.926193697939469e-8 5.271716748092626e-7 2.3518201011194467e-7 7311/1387/841/7706/8517/5300/4790/2033/7316/1540/5970/4792/7314/6233/3146 15 Sindbis_virus R-HSA-8939211 ESR-mediated signaling 26/379 223/10654 9.160795722989059e-8 6.020617502951928e-7 2.685919965202411e-7 5295/2962/7391/1025/8850/3725/1387/596/1956/4343/3845/2033/5241/3276/4602/5747/5469/3065/207/5451/6667/2099/5594/208/10498/4609 26 Sindbis_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 10/379 32/10654 9.234448642267336e-8 6.020617502951928e-7 2.685919965202411e-7 4089/7311/4088/7316/9040/10273/4087/4738/7314/6233 10 Sindbis_virus R-HSA-73863 RNA Polymerase I Transcription Termination 10/379 32/10654 9.234448642267336e-8 6.020617502951928e-7 2.685919965202411e-7 404672/2967/902/2965/2068/2071/1022/4331/2966/2968 10 Sindbis_virus R-HSA-9012852 Signaling by NOTCH3 12/379 49/10654 9.685576273257006e-8 6.273468030586728e-7 2.7987217301465036e-7 22938/8850/7311/1387/1956/2033/7316/4851/3280/7314/6233/11060 12 Sindbis_virus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 14/379 69/10654 1.0650941503565609e-7 6.853950019502286e-7 3.057686556047543e-7 3306/6119/3303/6118/9883/9972/472/23636/23411/8021/6117/9531/5594/4927 14 Sindbis_virus R-HSA-6804760 Regulation of TP53 Activity through Methylation 8/379 19/10654 1.2770141875949362e-7 8.033468124120306e-7 3.5838935813166166e-7 7311/472/2033/7316/7157/7314/6233/4193 8 Sindbis_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 16/379 92/10654 1.2774873158261795e-7 8.033468124120306e-7 3.5838935813166166e-7 8454/7311/3725/8517/4790/5599/7334/7316/57162/5970/4792/51231/5594/7314/6233/3146 16 Sindbis_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 10/379 33/10654 1.2833695889053029e-7 8.033468124120306e-7 3.5838935813166166e-7 7311/8517/4790/7334/7316/5970/4792/7314/6233/3146 10 Sindbis_virus R-HSA-5693568 Resolution of D-loop Structures through Holliday Junction Intermediates 10/379 33/10654 1.2833695889053029e-7 8.033468124120306e-7 3.5838935813166166e-7 672/5932/4683/472/5888/580/7486/10111/641/675 10 Sindbis_virus R-HSA-400253 Circadian Clock 14/379 70/10654 1.2889217272806545e-7 8.033468124120306e-7 3.5838935813166166e-7 8454/7311/3091/1387/23054/23411/8841/2908/2033/7316/5469/10498/7314/6233 14 Sindbis_virus R-HSA-5621481 C-type lectin receptors (CLRs) 20/379 142/10654 1.338970245507691e-7 8.29324695811326e-7 3.699786204692304e-7 8454/7311/1387/4067/841/4773/8517/5698/4790/3845/2033/7334/7316/4772/5970/4792/9040/997/7314/6233 20 Sindbis_virus R-HSA-1989781 PPARA activates gene expression 18/379 117/10654 1.4677341429682851e-7 9.034313886220935e-7 4.0303912392721794e-7 9968/1387/4899/23054/10001/8841/9439/4520/2033/9967/9440/5469/9443/9282/1024/6667/10498/9862 18 Sindbis_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 16/379 93/10654 1.493553876084097e-7 9.080441050302699e-7 4.05096950568499e-7 8454/7311/3725/8517/4790/5599/7334/7316/57162/5970/4792/51231/5594/7314/6233/3146 16 Sindbis_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 16/379 93/10654 1.493553876084097e-7 9.080441050302699e-7 4.05096950568499e-7 8454/7311/3725/8517/4790/5599/7334/7316/57162/5970/4792/51231/5594/7314/6233/3146 16 Sindbis_virus R-HSA-9013694 Signaling by NOTCH4 15/379 82/10654 1.5883804285134279e-7 9.598079296687848e-7 4.281898459407187e-7 8454/22938/8850/7311/1387/4088/5698/2033/7316/9978/4851/207/3280/7314/6233 15 Sindbis_virus R-HSA-168255 Influenza Life Cycle 20/379 144/10654 1.6934268682687376e-7 1.0170824402753448e-6 4.53741170445212e-7 2962/7311/3303/9883/9972/6202/6123/23636/6189/8021/6194/6134/6147/6143/9045/6157/200916/4927/11224/6233 20 Sindbis_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 16/379 94/10654 1.7423169238244013e-7 1.0388229159452681e-6 4.634400389792476e-7 8454/7311/3725/841/8517/4790/5599/7334/7316/5970/4792/51231/5594/7314/6233/3146 16 Sindbis_virus R-HSA-4085377 SUMOylation of SUMOylation proteins 10/379 34/10654 1.7610721481211408e-7 1.0388229159452681e-6 4.634400389792476e-7 9883/9972/7341/6613/23636/8021/10210/7329/51588/4927 10 Sindbis_virus R-HSA-5693537 Resolution of D-Loop Structures 10/379 34/10654 1.7610721481211408e-7 1.0388229159452681e-6 4.634400389792476e-7 672/5932/4683/472/5888/580/7486/10111/641/675 10 Sindbis_virus R-HSA-69202 Cyclin E associated events during G1/S transition 15/379 83/10654 1.876821906839548e-7 1.1001241131393308e-6 4.907877502984958e-7 8454/1017/7311/902/5698/7316/1869/1022/4331/1026/207/208/4609/7314/6233 15 Sindbis_virus R-HSA-162594 Early Phase of HIV Life Cycle 7/379 14/10654 1.8871957541239782e-7 1.1001241131393308e-6 4.907877502984958e-7 2237/3978/3981/8815/3159/2547/7520 7 Sindbis_virus R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 18/379 119/10654 1.9117291106736888e-7 1.1079085079986115e-6 4.942605272286546e-7 9968/1387/4899/23054/10001/8841/9439/4520/2033/9967/9440/5469/9443/9282/1024/6667/10498/9862 18 Sindbis_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 16/379 95/10654 2.0281385806545002e-7 1.16178342972752e-6 5.182952259658595e-7 8454/7311/3725/8517/4790/5599/7334/7316/57162/5970/4792/51231/5594/7314/6233/3146 16 Sindbis_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 16/379 95/10654 2.0281385806545002e-7 1.16178342972752e-6 5.182952259658595e-7 8454/7311/3725/8517/4790/5599/7334/7316/57162/5970/4792/51231/5594/7314/6233/3146 16 Sindbis_virus R-HSA-674695 RNA Polymerase II Pre-transcription Events 15/379 84/10654 2.2118403810214363e-7 1.259732079076002e-6 5.619921113303105e-7 2962/404672/1025/6884/6749/2967/902/2965/11198/2068/2071/1022/4331/2966/2968 15 Sindbis_virus R-HSA-8953750 Transcriptional Regulation by E2F6 10/379 35/10654 2.388174158568351e-7 1.3523889092235632e-6 6.033282084804256e-7 672/5932/5888/23512/648/1869/1111/2146/6045/6241 10 Sindbis_virus R-HSA-168273 Influenza Viral RNA Transcription and Replication 19/379 134/10654 2.4856166057157125e-7 1.3995716228774267e-6 6.243773770338514e-7 2962/7311/9883/9972/6202/6123/23636/6189/8021/6194/6134/6147/6143/9045/6157/200916/4927/11224/6233 19 Sindbis_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 15/379 85/10654 2.6000180779940756e-7 1.4557163363232365e-6 6.494246760377709e-7 8454/1017/7311/902/5698/7316/1869/1022/4331/1026/207/208/4609/7314/6233 15 Sindbis_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 16/379 97/10654 2.73096653074359e-7 1.5204426022285943e-6 6.783003801965157e-7 8454/7311/3725/8517/4790/5599/7334/7316/57162/5970/4792/51231/5594/7314/6233/3146 16 Sindbis_virus R-HSA-73854 RNA Polymerase I Promoter Clearance 17/379 110/10654 3.0567182728500845e-7 1.6922948650248233e-6 7.549671711832023e-7 404672/57504/8850/2967/902/2965/2074/2068/3066/3065/2071/1107/1022/4331/1108/2966/2968 17 Sindbis_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 16/379 98/10654 3.1594060899162845e-7 1.7298184724348276e-6 7.717072159144167e-7 8454/7311/3725/8517/4790/5599/7334/7316/57162/5970/4792/51231/5594/7314/6233/3146 16 Sindbis_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 16/379 98/10654 3.1594060899162845e-7 1.7298184724348276e-6 7.717072159144167e-7 8454/7311/3725/8517/4790/5599/7334/7316/57162/5970/4792/51231/5594/7314/6233/3146 16 Sindbis_virus R-HSA-168638 NOD1/2 Signaling Pathway 10/379 36/10654 3.203015648234691e-7 1.7440596194508675e-6 7.780604813525566e-7 7311/834/841/8517/7334/7316/1540/842/7314/6233 10 Sindbis_virus R-HSA-937039 IRAK1 recruits IKK complex 7/379 15/10654 3.4306360753338026e-7 1.8476958427477165e-6 8.242947091763142e-7 7311/8517/7334/7316/57162/7314/6233 7 Sindbis_virus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 7/379 15/10654 3.4306360753338026e-7 1.8476958427477165e-6 8.242947091763142e-7 7311/8517/7334/7316/57162/7314/6233 7 Sindbis_virus R-HSA-166166 MyD88-independent TLR4 cascade 16/379 99/10654 3.647878669676178e-7 1.9435740654027377e-6 8.670679350673428e-7 8454/7311/3725/841/8517/4790/5599/7334/7316/5970/4792/51231/5594/7314/6233/3146 16 Sindbis_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 16/379 99/10654 3.647878669676178e-7 1.9435740654027377e-6 8.670679350673428e-7 8454/7311/3725/841/8517/4790/5599/7334/7316/5970/4792/51231/5594/7314/6233/3146 16 Sindbis_virus R-HSA-73864 RNA Polymerase I Transcription 17/379 112/10654 3.987108572984467e-7 2.112954329319576e-6 9.426319170579657e-7 404672/57504/8850/2967/902/2965/2074/2068/3066/3065/2071/1107/1022/4331/1108/2966/2968 17 Sindbis_virus R-HSA-449147 Signaling by Interleukins 39/379 461/10654 4.016883753339663e-7 2.1174105316806414e-6 9.446199195983531e-7 5295/8454/7124/2308/7311/3091/834/3725/596/4067/11009/4088/8517/836/5698/4790/2335/5599/6597/7334/7316/1511/57162/9978/7412/7157/5970/4792/1026/207/942/5451/51231/5594/8878/4609/7314/6233/3146 39 Sindbis_virus R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 9/379 29/10654 4.41884236388884e-7 2.316969726250709e-6 1.0336473365821847e-6 4089/2308/4287/4088/2908/3066/3065/4087/23410 9 Sindbis_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 16/379 101/10654 4.835286283848681e-7 2.5219835301547596e-6 1.1251081657708844e-6 8454/7311/841/4773/8517/5698/4790/7334/7316/4772/5970/4792/9040/997/7314/6233 16 Sindbis_virus R-HSA-446652 Interleukin-1 family signaling 19/379 140/10654 4.988416194718107e-7 2.5882306015526932e-6 1.154662332202593e-6 8454/7311/834/4088/8517/5698/4790/5599/7334/7316/1511/57162/9978/5970/4792/8878/7314/6233/3146 19 Sindbis_virus R-HSA-5689896 Ovarian tumor domain proteases 10/379 38/10654 5.589330692731175e-7 2.8699620292728465e-6 1.2803484542934788e-6 7311/7706/8517/7316/5728/7157/2099/7314/6233/7415 10 Sindbis_virus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 10/379 38/10654 5.589330692731175e-7 2.8699620292728465e-6 1.2803484542934788e-6 7341/1387/1956/4605/2033/1026/7329/2099/4609/4869 10 Sindbis_virus R-HSA-168254 Influenza Infection 20/379 155/10654 5.710862084579359e-7 2.91724965248358e-6 1.301444425134743e-6 2962/7311/3303/9883/9972/6202/6123/23636/6189/8021/6194/6134/6147/6143/9045/6157/200916/4927/11224/6233 20 Sindbis_virus R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 7/379 16/10654 5.913090845183918e-7 2.989731136519011e-6 1.3337798898911094e-6 22938/8850/1387/2033/4851/3280/6928 7 Sindbis_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 7/379 16/10654 5.913090845183918e-7 2.989731136519011e-6 1.3337798898911094e-6 8454/7311/8517/4790/7316/7314/6233 7 Sindbis_virus R-HSA-913531 Interferon Signaling 23/379 199/10654 6.016305774748423e-7 3.0264766613074553e-6 1.350172816133763e-6 7311/9883/23650/9972/7341/23636/10437/7706/5300/8021/4940/1981/7334/7316/7412/816/817/3660/9830/4927/7314/6233/8554 23 Sindbis_virus R-HSA-6804758 Regulation of TP53 Activity through Acetylation 9/379 30/10654 6.116176425318989e-7 3.06117719065208e-6 1.3656534283008908e-6 5300/2033/3066/3065/7157/1107/207/208/1108 9 Sindbis_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 14/379 80/10654 7.276252905503866e-7 3.623500818771021e-6 1.6165174399955694e-6 7311/9883/9972/23636/7706/5300/8021/4940/1981/7334/7316/4927/7314/6233 14 Sindbis_virus R-HSA-1500620 Meiosis 17/379 118/10654 8.527043125271079e-7 4.22514986857182e-6 1.8849253224283438e-6 672/3306/4000/5932/1017/6119/7014/6118/4683/472/5888/6117/54386/10111/7329/641/675 17 Sindbis_virus R-HSA-6783310 Fanconi Anemia Pathway 10/379 40/10654 9.404052432160007e-7 4.636525353368441e-6 2.0684482961545973e-6 6119/7311/6118/2177/6117/2072/7316/7314/6233/2067 10 Sindbis_virus R-HSA-4655427 SUMOylation of DNA methylation proteins 7/379 17/10654 9.746124222477554e-7 4.78139064577983e-6 2.1330756505683027e-6 7341/84733/648/8535/1786/7329/6045 7 Sindbis_virus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 15/379 95/10654 1.1535438485832121e-6 5.631339674610656e-6 2.51225520562587e-6 7311/26986/6202/6123/6189/6194/6134/1981/6147/6143/9045/6157/200916/11224/6233 15 Sindbis_virus R-HSA-1169408 ISG15 antiviral mechanism 13/379 72/10654 1.2553759839787062e-6 6.098419608445577e-6 2.7206290674461127e-6 7311/9883/9972/23636/7706/5300/8021/1981/7334/7316/4927/7314/6233 13 Sindbis_virus R-HSA-9018519 Estrogen-dependent gene expression 19/379 150/10654 1.459680426844241e-6 7.056308795134843e-6 3.147962923104397e-6 2962/7391/1025/8850/3725/1387/596/4343/2033/5241/3276/4602/5469/3065/5451/6667/2099/10498/4609 19 Sindbis_virus R-HSA-5654738 Signaling by FGFR2 13/379 73/10654 1.4788931202998384e-6 7.114480981636601e-6 3.173914719090098e-6 5295/2962/7073/7311/3178/3845/7316/673/7072/5594/7314/6233/3187 13 Sindbis_virus R-HSA-186712 Regulation of beta-cell development 10/379 42/10654 1.5317900874885299e-6 7.29809604183237e-6 3.2558291333258226e-6 22938/2308/8850/1387/2033/4851/207/208/3280/6928 10 Sindbis_virus R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 10/379 42/10654 1.5317900874885299e-6 7.29809604183237e-6 3.2558291333258226e-6 7311/7316/1499/3065/7088/207/6934/208/7314/6233 10 Sindbis_virus R-HSA-2559580 Oxidative Stress Induced Senescence 17/379 125/10654 1.9417499501950388e-6 9.207053591594656e-6 4.107453936448836e-6 7311/3725/84733/4343/5599/23512/648/7316/1869/2146/7157/8535/6045/5594/7314/6233/4193 17 Sindbis_virus R-HSA-450294 MAP kinase activation 12/379 64/10654 2.128112945810317e-6 1.004266632999059e-5 4.480237780653299e-6 8454/7311/3725/8517/4790/5599/7334/7316/51231/5594/7314/6233 12 Sindbis_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 7/379 19/10654 2.373773897312543e-6 1.1096273265267595e-5 4.9502732714561476e-6 5295/7311/1956/3845/7316/7314/6233 7 Sindbis_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 7/379 19/10654 2.373773897312543e-6 1.1096273265267595e-5 4.9502732714561476e-6 5295/7311/1956/3845/7316/7314/6233 7 Sindbis_virus R-HSA-8848021 Signaling by PTK6 11/379 54/10654 2.413121205157418e-6 1.1174780907995334e-5 4.9852971282150304e-6 1017/7311/3091/1956/2908/9564/3845/7316/207/7314/6233 11 Sindbis_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 11/379 54/10654 2.413121205157418e-6 1.1174780907995334e-5 4.9852971282150304e-6 1017/7311/3091/1956/2908/9564/3845/7316/207/7314/6233 11 Sindbis_virus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 6/379 13/10654 2.704568678081489e-6 1.2466174697575607e-5 5.561414172799145e-6 7311/7316/207/208/7314/6233 6 Sindbis_virus R-HSA-9006931 Signaling by Nuclear Receptors 28/379 299/10654 2.7185090891675987e-6 1.2472419015579121e-5 5.56419989010912e-6 5295/2962/7391/1025/8850/3725/1387/596/1956/8841/5914/4343/3845/2033/5241/3276/4602/5747/5469/3065/207/5451/6667/2099/5594/208/10498/4609 28 Sindbis_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 17/379 129/10654 3.0219607268727786e-6 1.380075152226232e-5 6.156796047958123e-6 8454/7311/3725/841/8517/4790/5599/7334/7316/57162/5970/4792/51231/5594/7314/6233/3146 17 Sindbis_virus R-HSA-9020702 Interleukin-1 signaling 15/379 103/10654 3.2921607063299727e-6 1.4965739724646803e-5 6.676520988211437e-6 8454/7311/8517/5698/4790/7334/7316/57162/9978/5970/4792/8878/7314/6233/3146 15 Sindbis_virus R-HSA-5689880 Ub-specific processing proteases 23/379 220/10654 3.467358902121024e-6 1.56901948493239e-5 6.999715159292622e-6 4089/81847/409/7311/3091/9097/4088/8517/5698/7316/5728/1540/5423/7157/4792/8658/4087/9100/1643/4609/7314/6233/4193 23 Sindbis_virus R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 7/379 20/10654 3.540893299371996e-6 1.5950114816716584e-5 7.115670745149465e-6 22938/8850/1387/4088/2033/4851/3280 7 Sindbis_virus R-HSA-176187 Activation of ATR in response to replication stress 9/379 37/10654 4.263407888392142e-6 1.9031699177462222e-5 8.490428227238976e-6 5982/1017/6119/6118/5983/6117/5985/1111/5984 9 Sindbis_virus R-HSA-5689901 Metalloprotease DUBs 9/379 37/10654 4.263407888392142e-6 1.9031699177462222e-5 8.490428227238976e-6 672/8850/7311/580/2033/7316/7314/6233/51720 9 Sindbis_virus R-HSA-198323 AKT phosphorylates targets in the cytosol 6/379 14/10654 4.591455505083324e-6 2.0313091096149887e-5 9.062083233717088e-6 2931/842/1026/207/208/4193 6 Sindbis_virus R-HSA-8941856 RUNX3 regulates NOTCH signaling 6/379 14/10654 4.591455505083324e-6 2.0313091096149887e-5 9.062083233717088e-6 22938/8850/1387/2033/4851/3280 6 Sindbis_virus R-HSA-8948751 Regulation of PTEN stability and activity 12/379 69/10654 4.864710232045745e-6 2.1426345955365925e-5 9.558728877002166e-6 81847/7311/5698/7316/5728/8658/10273/207/208/7314/6233/11060 12 Sindbis_virus R-HSA-8863795 Downregulation of ERBB2 signaling 8/379 29/10654 5.302847687250211e-6 2.3252752469313977e-5 1.0373525983442425e-5 7311/1956/7316/10273/207/208/7314/6233 8 Sindbis_virus R-HSA-2871837 FCERI mediated NF-kB activation 13/379 82/10654 5.721643394636791e-6 2.497862821182846e-5 1.114347426731951e-5 8454/7311/4067/8517/5698/4790/7334/7316/5970/4792/997/7314/6233 13 Sindbis_virus R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 11/379 59/10654 6.013396216247329e-6 2.61371739048294e-5 1.1660325073055762e-5 7311/7336/5591/7334/7316/9781/79139/5111/7314/6233/7415 11 Sindbis_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 13/379 83/10654 6.569186311858155e-6 2.842822548057394e-5 1.2682409795359344e-5 8454/7311/4773/8517/5698/4790/3845/7316/4772/5970/4792/7314/6233 13 Sindbis_virus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 10/379 49/10654 6.848349661869363e-6 2.9507454412663213e-5 1.3163875780252324e-5 1017/2810/2033/3276/1869/7157/1026/5111/10498/4869 10 Sindbis_virus R-HSA-448424 Interleukin-17 signaling 12/379 72/10654 7.700221587657747e-6 3.30342839539776e-5 1.4737266196474158e-5 8454/7311/3725/8517/4790/5599/7334/7316/51231/5594/7314/6233 12 Sindbis_virus R-HSA-1227986 Signaling by ERBB2 10/379 50/10654 8.292884430619193e-6 3.542348478768802e-5 1.5803137299728045e-5 5295/7311/1956/3845/7316/10273/207/208/7314/6233 10 Sindbis_virus R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 15/379 111/10654 8.459396001125513e-6 3.59796628202377e-5 1.6051259636199302e-5 7311/26986/6202/6123/6189/6194/6134/1981/6147/6143/9045/6157/200916/11224/6233 15 Sindbis_virus R-HSA-202424 Downstream TCR signaling 14/379 98/10654 8.795958421726998e-6 3.725125981167289e-5 1.6618544926339806e-5 5295/8454/7311/8517/5698/4790/7334/7316/5728/5970/4792/997/7314/6233 14 Sindbis_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 15/379 112/10654 9.456339516118172e-6 3.987758493818344e-5 1.7790202001207764e-5 5295/8454/7311/4067/4773/8517/5698/4790/3845/7316/4772/5970/4792/7314/6233 15 Sindbis_virus R-HSA-168898 Toll-like Receptor Cascades 18/379 155/10654 9.555747682759089e-6 4.0126042176331595e-5 1.7901043830324786e-5 8454/7311/3725/841/8517/4790/5599/7334/7316/57162/5970/4792/51231/5594/1508/7314/6233/3146 18 Sindbis_virus R-HSA-8951664 Neddylation 23/379 234/10654 9.760457932136436e-6 4.081271650104307e-5 1.8207383217842788e-5 8454/7311/3091/83987/55832/5698/1642/8452/23363/8450/23038/7316/9978/10987/7428/9040/4738/7704/9820/1643/7314/6233/8451 23 Sindbis_virus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 7/379 23/10654 1.0208016089974188e-5 4.2430252344183166e-5 1.892899886829564e-5 7311/8517/5599/7334/7316/7314/6233 7 Sindbis_virus R-HSA-73887 Death Receptor Signalling 17/379 141/10654 1.0232926650110773e-5 4.2430252344183166e-5 1.892899886829564e-5 7124/7311/841/8841/8517/836/4790/5599/7316/1540/3066/3065/5970/4792/8878/7314/6233 17 Sindbis_virus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 19/379 171/10654 1.0327990722429523e-5 4.264599502469857e-5 1.9025246067633332e-5 7311/26986/6202/6123/6189/6194/6134/5698/1981/7316/6147/9978/6143/9045/6157/200916/11224/7314/6233 19 Sindbis_virus R-HSA-190236 Signaling by FGFR 13/379 87/10654 1.1172370918945231e-5 4.594116008578723e-5 2.0495286245717392e-5 5295/2962/7073/7311/3178/3845/7316/673/7072/5594/7314/6233/3187 13 Sindbis_virus R-HSA-1295596 Spry regulation of FGF signaling 6/379 16/10654 1.1523161381475525e-5 4.6993633452848744e-5 2.096481602867542e-5 7311/7316/673/5594/7314/6233 6 Sindbis_virus R-HSA-205043 NRIF signals cell death from the nucleus 6/379 16/10654 1.1523161381475525e-5 4.6993633452848744e-5 2.096481602867542e-5 7311/5599/7316/8878/7314/6233 6 Sindbis_virus R-HSA-8941326 RUNX2 regulates bone development 8/379 32/10654 1.1832975471959226e-5 4.8059338904555707e-5 2.1440248913817405e-5 4089/25/8841/10432/9759/10413/5594/3280 8 Sindbis_virus R-HSA-3215018 Processing and activation of SUMO 5/379 10/10654 1.2065289484449916e-5 4.88028648126117e-5 2.177195094938331e-5 7341/6612/6613/29843/7329 5 Sindbis_virus R-HSA-927802 Nonsense-Mediated Decay (NMD) 15/379 115/10654 1.3102798582669694e-5 5.25703376333023e-5 2.3452697228729052e-5 7311/26986/6202/6123/6189/6194/6134/1981/6147/6143/9045/6157/200916/11224/6233 15 Sindbis_virus R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 15/379 115/10654 1.3102798582669694e-5 5.25703376333023e-5 2.3452697228729052e-5 7311/26986/6202/6123/6189/6194/6134/1981/6147/6143/9045/6157/200916/11224/6233 15 Sindbis_virus R-HSA-1474165 Reproduction 17/379 144/10654 1.3569393282093822e-5 5.422285783288297e-5 2.4189920112391363e-5 672/3306/4000/5932/1017/6119/7014/6118/4683/472/5888/6117/54386/10111/7329/641/675 17 Sindbis_virus R-HSA-156902 Peptide chain elongation 13/379 89/10654 1.4394189063122994e-5 5.7058565446219546e-5 2.5454986974785927e-5 7311/6202/6123/6189/6194/6134/6147/6143/9045/6157/200916/11224/6233 13 Sindbis_virus R-HSA-192823 Viral mRNA Translation 13/379 89/10654 1.4394189063122994e-5 5.7058565446219546e-5 2.5454986974785927e-5 7311/6202/6123/6189/6194/6134/6147/6143/9045/6157/200916/11224/6233 13 Sindbis_virus R-HSA-5357905 Regulation of TNFR1 signaling 8/379 33/10654 1.513965513612545e-5 5.9774494979682554e-5 2.6666618398711214e-5 7124/7311/841/8517/7316/1540/7314/6233 8 Sindbis_virus R-HSA-1643713 Signaling by EGFR in Cancer 7/379 25/10654 1.8819212240514244e-5 7.371477996185619e-5 3.288566316212183e-5 5295/7311/1956/3845/7316/7314/6233 7 Sindbis_virus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 7/379 25/10654 1.8819212240514244e-5 7.371477996185619e-5 3.288566316212183e-5 2308/2931/842/1026/207/208/4193 7 Sindbis_virus R-HSA-72613 Eukaryotic Translation Initiation 15/379 119/10654 1.9880509742257088e-5 7.726111825324225e-5 3.4467756828681025e-5 7311/26986/6202/6123/6189/6194/6134/1981/6147/6143/9045/6157/200916/11224/6233 15 Sindbis_virus R-HSA-72737 Cap-dependent Translation Initiation 15/379 119/10654 1.9880509742257088e-5 7.726111825324225e-5 3.4467756828681025e-5 7311/26986/6202/6123/6189/6194/6134/1981/6147/6143/9045/6157/200916/11224/6233 15 Sindbis_virus R-HSA-8852135 Protein ubiquitination 12/379 79/10654 2.0506718355771087e-5 7.938342926003573e-5 3.541456294993362e-5 7311/7336/5591/7334/7316/9781/79139/997/5111/7314/6233/7415 12 Sindbis_virus R-HSA-156842 Eukaryotic Translation Elongation 13/379 93/10654 2.3364308651450344e-5 8.939779873971927e-5 3.988217692992947e-5 7311/6202/6123/6189/6194/6134/6147/6143/9045/6157/200916/11224/6233 13 Sindbis_virus R-HSA-2408557 Selenocysteine synthesis 13/379 93/10654 2.3364308651450344e-5 8.939779873971927e-5 3.988217692992947e-5 7311/6202/6123/6189/6194/6134/6147/6143/9045/6157/200916/11224/6233 13 Sindbis_virus R-HSA-72764 Eukaryotic Translation Termination 13/379 93/10654 2.3364308651450344e-5 8.939779873971927e-5 3.988217692992947e-5 7311/6202/6123/6189/6194/6134/6147/6143/9045/6157/200916/11224/6233 13 Sindbis_virus R-HSA-69615 G1/S DNA Damage Checkpoints 11/379 68/10654 2.471580381314652e-5 9.420523684164692e-5 4.2026872880654e-5 1017/7311/472/5698/7316/1111/7157/1026/7314/6233/4193 11 Sindbis_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 7/379 26/10654 2.4971575256924793e-5 9.473747588236896e-5 4.2264315545801653e-5 7311/4088/7316/10273/4087/7314/6233 7 Sindbis_virus R-HSA-453274 Mitotic G2-G2/M phases 20/379 198/10654 2.5060329663170657e-5 9.473747588236896e-5 4.2264315545801653e-5 8454/1017/7311/4605/902/5698/2033/7316/9978/1869/203068/81027/7157/1022/4331/1026/1069/55755/7314/6233 20 Sindbis_virus R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 6/379 18/10654 2.5142236283615575e-5 9.473747588236896e-5 4.2264315545801653e-5 2810/2033/3276/7157/5111/10498 6 Sindbis_virus R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 19/379 185/10654 3.16678368696989e-5 1.1887434218890761e-4 5.30322627004527e-5 7311/83732/26168/6202/6123/6189/6194/134430/6134/55781/6147/6143/9045/51013/6157/200916/11224/6233/9188 19 Sindbis_virus R-HSA-1236394 Signaling by ERBB4 10/379 58/10654 3.268449849193189e-5 1.2222769058680945e-4 5.452825964890326e-5 5295/7311/1956/3845/5241/7316/10413/2099/7314/6233 10 Sindbis_virus R-HSA-5250941 Negative epigenetic regulation of rRNA expression 14/379 110/10654 3.362403185009685e-5 1.2526847956182698e-4 5.588481747938535e-5 404672/2967/23411/902/2965/2068/3066/3065/2071/1022/4331/1786/2966/2968 14 Sindbis_virus R-HSA-193704 p75 NTR receptor-mediated signalling 13/379 97/10654 3.68925984508532e-5 1.3693095529885964e-4 6.108768519360673e-5 7311/8841/836/4790/5599/7316/3066/3065/5970/4792/8878/7314/6233 13 Sindbis_virus R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 14/379 112/10654 4.1227427095281786e-5 1.5244918004262778e-4 6.801068098985997e-5 7311/6202/6123/6189/6194/6134/1981/6147/6143/9045/6157/200916/11224/6233 14 Sindbis_virus R-HSA-111465 Apoptotic cleavage of cellular proteins 8/379 38/10654 4.5630468022544706e-5 1.681033227150253e-4 7.499431253949825e-5 4000/8428/840/841/836/1499/4137/5747 8 Sindbis_virus R-HSA-912446 Meiotic recombination 12/379 86/10654 4.8933642883074555e-5 1.796045929523218e-4 8.012526320035601e-5 672/5932/1017/6119/6118/4683/472/5888/6117/10111/641/675 12 Sindbis_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 6/379 20/10654 4.941212770739238e-5 1.8069158139492932e-4 8.06101908607683e-5 7311/8517/7334/7316/7314/6233 6 Sindbis_virus R-HSA-162909 Host Interactions of HIV factors 15/379 129/10654 5.198597509956839e-5 1.894047842782069e-4 8.449732794821488e-5 1025/7311/9883/9972/23636/8021/5698/8815/7316/3159/9978/4927/7314/6233/4869 15 Sindbis_virus R-HSA-5205647 Mitophagy 7/379 29/10654 5.4026522394123856e-5 1.9611825528416388e-4 8.749234395809532e-5 8408/7311/84557/7316/8878/7314/6233 7 Sindbis_virus R-HSA-209543 p75NTR recruits signalling complexes 5/379 13/10654 5.639003051264399e-5 2.0395080378843135e-4 9.098660320902987e-5 7311/7316/8878/7314/6233 5 Sindbis_virus R-HSA-72689 Formation of a pool of free 40S subunits 13/379 101/10654 5.6804977377587006e-5 2.0470448211341353e-4 9.13228344443504e-5 7311/6202/6123/6189/6194/6134/6147/6143/9045/6157/200916/11224/6233 13 Sindbis_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 12/379 88/10654 6.165151394445971e-5 2.2136467506869413e-4 9.87552854945579e-5 7311/3303/26986/8021/5698/1981/7316/51013/207/7314/6233/1994 12 Sindbis_virus R-HSA-1234174 Cellular response to hypoxia 11/379 75/10654 6.31829610760006e-5 2.260444564126953e-4 1.0084303116823199e-4 7311/3091/1387/5698/2033/7316/9978/7428/768/7314/6233 11 Sindbis_virus R-HSA-8868773 rRNA processing in the nucleus and cytosol 19/379 195/10654 6.541254239606107e-5 2.3317924285790113e-4 1.0402600456776088e-4 7311/83732/26168/6202/6123/6189/6194/134430/6134/55781/6147/6143/9045/51013/6157/200916/11224/6233/9188 19 Sindbis_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 6/379 21/10654 6.711702656993493e-5 2.3839775387385492e-4 1.0635408850923476e-4 1387/4067/4790/3845/2033/5970 6 Sindbis_virus R-HSA-5654741 Signaling by FGFR3 8/379 40/10654 6.742677519612978e-5 2.3864262221201646e-4 1.0646332925704702e-4 5295/7311/3845/7316/673/5594/7314/6233 8 Sindbis_virus R-HSA-114452 Activation of BH3-only proteins 7/379 30/10654 6.833627935529845e-5 2.4014628667057007e-4 1.071341445659774e-4 2810/596/5599/1869/7157/207/208 7 Sindbis_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 7/379 30/10654 6.833627935529845e-5 2.4014628667057007e-4 1.071341445659774e-4 7124/7311/8517/7316/1540/7314/6233 7 Sindbis_virus R-HSA-69275 G2/M Transition 19/379 196/10654 7.011495723559819e-5 2.45526228340911e-4 1.0953424600688576e-4 8454/1017/7311/4605/902/5698/2033/7316/9978/203068/81027/7157/1022/4331/1026/1069/55755/7314/6233 19 Sindbis_virus R-HSA-2408522 Selenoamino acid metabolism 14/379 118/10654 7.378911161993237e-5 2.574824282230739e-4 1.1486815003844179e-4 7311/6202/6123/6189/6194/6134/7965/6147/6143/9045/6157/200916/11224/6233 14 Sindbis_virus R-HSA-2980766 Nuclear Envelope Breakdown 9/379 52/10654 7.863692826171459e-5 2.7247970596978725e-4 1.2155874077997838e-4 4000/9883/9972/23636/8021/7443/8815/7112/4927 9 Sindbis_virus R-HSA-75153 Apoptotic execution phase 9/379 52/10654 7.863692826171459e-5 2.7247970596978725e-4 1.2155874077997838e-4 4000/8428/840/841/836/1499/4137/5747/3146 9 Sindbis_virus R-HSA-202403 TCR signaling 14/379 119/10654 8.09769252036226e-5 2.79430521023503e-4 1.2465964079863112e-4 5295/8454/7311/8517/5698/4790/7334/7316/5728/5970/4792/997/7314/6233 14 Sindbis_virus R-HSA-5654743 Signaling by FGFR4 8/379 41/10654 8.120685172025113e-5 2.79430521023503e-4 1.2465964079863112e-4 5295/7311/3845/7316/673/5594/7314/6233 8 Sindbis_virus R-HSA-5205685 Pink/Parkin Mediated Mitophagy 6/379 22/10654 8.95395408469699e-5 3.0597822406671434e-4 1.3650311127305756e-4 7311/84557/7316/8878/7314/6233 6 Sindbis_virus R-HSA-912631 Regulation of signaling by CBL 6/379 22/10654 8.95395408469699e-5 3.0597822406671434e-4 1.3650311127305756e-4 5295/7311/4067/7316/7314/6233 6 Sindbis_virus R-HSA-376176 Signaling by ROBO receptors 20/379 218/10654 9.830163411001784e-5 3.3476604605851433e-4 1.4934594438852412e-4 7311/26986/25/6202/6123/6189/6194/6134/5698/1981/7316/6147/9978/6143/9045/6157/200916/11224/7314/6233 20 Sindbis_virus R-HSA-69563 p53-Dependent G1 DNA Damage Response 10/379 66/10654 1.0259357788672014e-4 3.4699739141890666e-4 1.5480259641610368e-4 1017/7311/472/5698/7316/7157/1026/7314/6233/4193 10 Sindbis_virus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 10/379 66/10654 1.0259357788672014e-4 3.4699739141890666e-4 1.5480259641610368e-4 1017/7311/472/5698/7316/7157/1026/7314/6233/4193 10 Sindbis_virus R-HSA-427413 NoRC negatively regulates rRNA expression 13/379 107/10654 1.0399401668862621e-4 3.505376548926142e-4 1.5638197998289657e-4 404672/2967/902/2965/2068/3066/3065/2071/1022/4331/1786/2966/2968 13 Sindbis_virus R-HSA-75893 TNF signaling 8/379 43/10654 1.1581386937369368e-4 3.890560832180693e-4 1.7356583456539285e-4 7124/7311/841/8517/7316/1540/7314/6233 8 Sindbis_virus R-HSA-1169091 Activation of NF-kappaB in B cells 10/379 67/10654 1.1684000448048536e-4 3.9117717716270604e-4 1.7451209773045466e-4 8454/7311/8517/5698/4790/7316/5970/4792/7314/6233 10 Sindbis_virus R-HSA-2691230 Signaling by NOTCH1 HD Domain Mutants in Cancer 5/379 15/10654 1.2403866655687494e-4 4.111114333038898e-4 1.8340517498288147e-4 7311/7316/4851/7314/6233 5 Sindbis_virus R-HSA-2691232 Constitutive Signaling by NOTCH1 HD Domain Mutants 5/379 15/10654 1.2403866655687494e-4 4.111114333038898e-4 1.8340517498288147e-4 7311/7316/4851/7314/6233 5 Sindbis_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 5/379 15/10654 1.2403866655687494e-4 4.111114333038898e-4 1.8340517498288147e-4 7311/7334/7316/7314/6233 5 Sindbis_virus R-HSA-72312 rRNA processing 19/379 205/10654 1.2789348599725537e-4 4.2247481541093354e-4 1.884746109433237e-4 7311/83732/26168/6202/6123/6189/6194/134430/6134/55781/6147/6143/9045/51013/6157/200916/11224/6233/9188 19 Sindbis_virus R-HSA-180910 Vpr-mediated nuclear import of PICs 7/379 33/10654 1.3078113532680408e-4 4.277363204912965e-4 1.9082187541169955e-4 9883/9972/23636/8021/8815/3159/4927 7 Sindbis_virus R-HSA-1980145 Signaling by NOTCH2 7/379 33/10654 1.3078113532680408e-4 4.277363204912965e-4 1.9082187541169955e-4 7311/2033/7316/3002/3280/7314/6233 7 Sindbis_virus R-HSA-9022692 Regulation of MECP2 expression and activity 7/379 33/10654 1.3078113532680408e-4 4.277363204912965e-4 1.9082187541169955e-4 8841/4343/28996/816/3066/3065/817 7 Sindbis_virus R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 9/379 56/10654 1.4282917151294946e-4 4.6560430582017403e-4 2.0771555413933094e-4 1387/4899/11232/23054/8841/5469/23409/10498/23410 9 Sindbis_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 11/379 82/10654 1.4456667984438933e-4 4.6972321221570433e-4 2.095530820867766e-4 8454/7311/5698/7316/1499/9978/3065/7088/6934/7314/6233 11 Sindbis_virus R-HSA-3371571 HSF1-dependent transactivation 6/379 24/10654 1.5206059170722933e-4 4.876765255076514e-4 2.1756242042935214e-4 3306/3303/1387/2033/816/817 6 Sindbis_virus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 6/379 24/10654 1.5206059170722933e-4 4.876765255076514e-4 2.1756242042935214e-4 7311/8517/7334/7316/7314/6233 6 Sindbis_virus R-HSA-933542 TRAF6 mediated NF-kB activation 6/379 24/10654 1.5206059170722933e-4 4.876765255076514e-4 2.1756242042935214e-4 7706/8517/4790/5970/4792/3146 6 Sindbis_virus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 6/379 24/10654 1.5206059170722933e-4 4.876765255076514e-4 2.1756242042935214e-4 596/1956/5747/207/5594/208 6 Sindbis_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 7/379 34/10654 1.5971217241726396e-4 5.105637511790599e-4 2.2777287747114045e-4 7311/7706/5300/7316/1540/7314/6233 7 Sindbis_virus R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 13/379 112/10654 1.6615652728030366e-4 5.294569727806461e-4 2.3620152803427834e-4 7311/6202/6123/6189/6194/6134/6147/6143/9045/6157/200916/11224/6233 13 Sindbis_virus R-HSA-6802957 Oncogenic MAPK signaling 10/379 71/10654 1.9172090760367336e-4 6.069072096238608e-4 2.707536545138048e-4 4000/409/27044/2335/3845/673/816/817/5245/5594 10 Sindbis_virus R-HSA-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle 7/379 35/10654 1.9361215599105722e-4 6.069072096238608e-4 2.707536545138048e-4 7311/5887/7316/79139/7314/6233/7415 7 Sindbis_virus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 6/379 25/10654 1.9413681680198168e-4 6.069072096238608e-4 2.707536545138048e-4 701/7311/9184/7316/7314/6233 6 Sindbis_virus R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus 6/379 25/10654 1.9413681680198168e-4 6.069072096238608e-4 2.707536545138048e-4 7311/1956/7316/7314/6233/11060 6 Sindbis_virus R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 6/379 25/10654 1.9413681680198168e-4 6.069072096238608e-4 2.707536545138048e-4 22938/8850/1387/2033/4851/3280 6 Sindbis_virus R-HSA-937041 IKK complex recruitment mediated by RIP1 6/379 25/10654 1.9413681680198168e-4 6.069072096238608e-4 2.707536545138048e-4 7311/8517/7334/7316/7314/6233 6 Sindbis_virus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 8/379 47/10654 2.2181443051910303e-4 6.847915907926203e-4 3.0549946161017634e-4 409/2335/3845/673/816/817/5245/5594 8 Sindbis_virus R-HSA-6802949 Signaling by RAS mutants 8/379 47/10654 2.2181443051910303e-4 6.847915907926203e-4 3.0549946161017634e-4 409/2335/3845/673/816/817/5245/5594 8 Sindbis_virus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 8/379 47/10654 2.2181443051910303e-4 6.847915907926203e-4 3.0549946161017634e-4 409/2335/3845/673/816/817/5245/5594 8 Sindbis_virus R-HSA-9649948 Signaling downstream of RAS mutants 8/379 47/10654 2.2181443051910303e-4 6.847915907926203e-4 3.0549946161017634e-4 409/2335/3845/673/816/817/5245/5594 8 Sindbis_virus R-HSA-176033 Interactions of Vpr with host cellular proteins 7/379 36/10654 2.330926564889384e-4 7.173752254053974e-4 3.200356839665058e-4 9883/9972/23636/8021/8815/3159/4927 7 Sindbis_virus R-HSA-2219528 PI3K/AKT Signaling in Cancer 12/379 101/10654 2.362251585172391e-4 7.247651148315293e-4 3.2333246399622107e-4 5295/2308/2931/1956/5728/842/1026/207/942/2099/208/4193 12 Sindbis_virus R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 5/379 17/10654 2.4097589576732226e-4 7.365411240252917e-4 3.2858598129547245e-4 4089/2308/4088/1026/4087 5 Sindbis_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 10/379 73/10654 2.4220247072774707e-4 7.365411240252917e-4 3.2858598129547245e-4 8454/7311/2908/5698/7316/9978/10273/2099/7314/6233 10 Sindbis_virus R-HSA-201681 TCF dependent signaling in response to WNT 20/379 233/10654 2.4229304382668526e-4 7.365411240252917e-4 3.2858598129547245e-4 81847/7311/1387/5698/8452/2033/6597/7316/1499/9978/3065/7088/8658/207/6259/6934/208/4609/7314/6233 20 Sindbis_virus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 4/379 10/10654 2.7914711893266487e-4 8.459779659396663e-4 3.774079831054861e-4 7311/7316/7314/6233 4 Sindbis_virus R-HSA-1538133 G0 and Early G1 6/379 27/10654 3.0551401488133667e-4 9.230621608152581e-4 4.117968108156656e-4 1017/4605/1869/3065/5111/4609 6 Sindbis_virus R-HSA-195721 Signaling by WNT 25/379 331/10654 3.151440339004657e-4 9.492636401074818e-4 4.2348582383041304e-4 81847/8454/409/7311/1387/5698/4343/8452/3845/2033/6597/7316/1499/9978/4772/3065/7088/8658/207/6259/6934/208/4609/7314/6233 25 Sindbis_virus R-HSA-1368082 RORA activates gene expression 5/379 18/10654 3.239888417225948e-4 9.700088886619077e-4 4.3274070129906134e-4 1387/23054/2033/5469/10498 5 Sindbis_virus R-HSA-5675482 Regulation of necroptotic cell death 5/379 18/10654 3.239888417225948e-4 9.700088886619077e-4 4.3274070129906134e-4 7311/841/7316/7314/6233 5 Sindbis_virus R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 7/379 38/10654 3.314627380587985e-4 9.893963054706907e-4 4.4138982239916096e-4 84733/2033/648/6597/28996/8535/6045 7 Sindbis_virus R-HSA-5654736 Signaling by FGFR1 8/379 50/10654 3.4507140220232756e-4 0.0010269242029504703 4.5813178101778915e-4 5295/7311/3845/7316/673/5594/7314/6233 8 Sindbis_virus R-HSA-9009391 Extra-nuclear estrogen signaling 10/379 77/10654 3.769503513211902e-4 0.0011184365214350284 4.989572882284901e-4 5295/596/1956/3845/3276/5747/207/2099/5594/208 10 Sindbis_virus R-HSA-877300 Interferon gamma signaling 11/379 92/10654 4.040156749170068e-4 0.0011951627875903096 5.331864366540231e-4 23650/7341/10437/7706/4940/7412/816/817/3660/9830/8554 11 Sindbis_virus R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 4/379 11/10654 4.263883980760433e-4 0.0012464628392134481 5.560724334480304e-4 3091/1387/2033/768 4 Sindbis_virus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 4/379 11/10654 4.263883980760433e-4 0.0012464628392134481 5.560724334480304e-4 7311/7316/7314/6233 4 Sindbis_virus R-HSA-9614399 Regulation of localization of FOXO transcription factors 4/379 11/10654 4.263883980760433e-4 0.0012464628392134481 5.560724334480304e-4 2308/2810/207/208 4 Sindbis_virus R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 4/379 11/10654 4.263883980760433e-4 0.0012464628392134481 5.560724334480304e-4 7311/7316/7314/6233 4 Sindbis_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 12/379 108/10654 4.4208153997624995e-4 0.0012885376650484226 5.748428693189627e-4 5295/7124/2308/3091/596/2335/7412/7157/1026/207/5451/4609 12 Sindbis_virus R-HSA-383280 Nuclear Receptor transcription pathway 8/379 52/10654 4.546322183978463e-4 0.0013212332212089904 5.894290221549482e-4 5914/2908/7068/5241/7182/7067/5469/2099 8 Sindbis_virus R-HSA-5675221 Negative regulation of MAPK pathway 7/379 40/10654 4.606034747311457e-4 0.0013337865937704605 5.950293370689824e-4 7311/3845/7316/673/5594/7314/6233 7 Sindbis_virus R-HSA-5654732 Negative regulation of FGFR3 signaling 6/379 29/10654 4.6164359400935215e-4 0.0013337865937704605 5.950293370689824e-4 7311/7316/673/5594/7314/6233 6 Sindbis_virus R-HSA-5213460 RIPK1-mediated regulated necrosis 5/379 20/10654 5.528182627455704e-4 0.001578797978042825 7.043339006617308e-4 7311/841/7316/7314/6233 5 Sindbis_virus R-HSA-5218859 Regulated Necrosis 5/379 20/10654 5.528182627455704e-4 0.001578797978042825 7.043339006617308e-4 7311/841/7316/7314/6233 5 Sindbis_virus R-HSA-622312 Inflammasomes 5/379 20/10654 5.528182627455704e-4 0.001578797978042825 7.043339006617308e-4 834/596/10628/4790/5970 5 Sindbis_virus R-HSA-8876384 Listeria monocytogenes entry into host cells 5/379 20/10654 5.528182627455704e-4 0.001578797978042825 7.043339006617308e-4 7311/7316/1499/7314/6233 5 Sindbis_virus R-HSA-6802952 Signaling by BRAF and RAF fusions 9/379 67/10654 5.713222563281629e-4 0.0016269550460379582 7.258177485112778e-4 4000/409/27044/2335/3845/673/816/817/5594 9 Sindbis_virus R-HSA-9604323 Negative regulation of NOTCH4 signaling 8/379 54/10654 5.908561988003898e-4 0.0016777607249604193 7.484831955848703e-4 8454/7311/5698/7316/9978/207/7314/6233 8 Sindbis_virus R-HSA-264870 Caspase-mediated cleavage of cytoskeletal proteins 4/379 12/10654 6.217117091336215e-4 0.0017503304083847128 7.808580078831371e-4 840/841/836/4137 4 Sindbis_virus R-HSA-3371511 HSF1 activation 4/379 12/10654 6.217117091336215e-4 0.0017503304083847128 7.808580078831371e-4 6119/6118/6117/7415 4 Sindbis_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 4/379 12/10654 6.217117091336215e-4 0.0017503304083847128 7.808580078831371e-4 7311/7316/7314/6233 4 Sindbis_virus R-HSA-2122948 Activated NOTCH1 Transmits Signal to the Nucleus 6/379 31/10654 6.738200070813364e-4 0.0018863153305582042 8.415236484512677e-4 409/7311/7316/4851/7314/6233 6 Sindbis_virus R-HSA-5654733 Negative regulation of FGFR4 signaling 6/379 31/10654 6.738200070813364e-4 0.0018863153305582042 8.415236484512677e-4 7311/7316/673/5594/7314/6233 6 Sindbis_virus R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs 13/379 130/10654 7.190690427142265e-4 0.002007316679802249 8.95504812275686e-4 7311/25/902/5698/7316/6886/4602/6929/1022/4331/10413/7314/6233 13 Sindbis_virus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 8/379 56/10654 7.582972521439983e-4 0.0021108780249289387 9.417056354242438e-4 7311/3303/26986/5698/1981/7316/7314/6233 8 Sindbis_virus R-HSA-3247509 Chromatin modifying enzymes 21/379 274/10654 7.789108181480393e-4 0.0021561469854321424 9.619010397594134e-4 57504/8850/1387/8841/4790/2033/23512/6597/3276/8473/2146/3066/3065/5978/5970/1107/79084/51147/63976/1108/10498 21 Sindbis_virus R-HSA-4839726 Chromatin organization 21/379 274/10654 7.789108181480393e-4 0.0021561469854321424 9.619010397594134e-4 57504/8850/1387/8841/4790/2033/23512/6597/3276/8473/2146/3066/3065/5978/5970/1107/79084/51147/63976/1108/10498 21 Sindbis_virus R-HSA-69541 Stabilization of p53 8/379 57/10654 8.55264212573402e-4 0.0023609104029533186 0.0010532501664882827 7311/472/5698/7316/7157/7314/6233/4193 8 Sindbis_virus R-HSA-111461 Cytochrome c-mediated apoptotic response 4/379 13/10654 8.729657885207224e-4 0.002389804133768055 0.0010661402476845113 840/836/842/5594 4 Sindbis_virus R-HSA-2995383 Initiation of Nuclear Envelope Reformation 4/379 13/10654 8.729657885207224e-4 0.002389804133768055 0.0010661402476845113 4000/7443/8815/7112 4 Sindbis_virus R-HSA-2995410 Nuclear Envelope Reassembly 4/379 13/10654 8.729657885207224e-4 0.002389804133768055 0.0010661402476845113 4000/7443/8815/7112 4 Sindbis_virus R-HSA-9613829 Chaperone Mediated Autophagy 5/379 22/10654 8.85500004404422e-4 0.0024174394059635874 0.0010784689048857685 7311/7316/1068/7314/6233 5 Sindbis_virus R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 6/379 33/10654 9.545788429347735e-4 0.0025846656648862306 0.0011530719414225047 3303/9883/9972/23636/8021/4927 6 Sindbis_virus R-HSA-180746 Nuclear import of Rev protein 6/379 33/10654 9.545788429347735e-4 0.0025846656648862306 0.0011530719414225047 9883/9972/23636/8021/4927/4869 6 Sindbis_virus R-HSA-5654726 Negative regulation of FGFR1 signaling 6/379 33/10654 9.545788429347735e-4 0.0025846656648862306 0.0011530719414225047 7311/7316/673/5594/7314/6233 6 Sindbis_virus R-HSA-159227 Transport of the SLBP independent Mature mRNA 6/379 34/10654 0.0011249074151885258 0.0030293023055756227 0.001351433393533126 9883/9972/23636/8021/10482/4927 6 Sindbis_virus R-HSA-5654727 Negative regulation of FGFR2 signaling 6/379 34/10654 0.0011249074151885258 0.0030293023055756227 0.001351433393533126 7311/7316/673/5594/7314/6233 6 Sindbis_virus R-HSA-174490 Membrane binding and targetting of GAG proteins 4/379 14/10654 0.0011880852972778297 0.0031565483367354675 0.0014082004370161946 7311/7316/7314/6233 4 Sindbis_virus R-HSA-174495 Synthesis And Processing Of GAG, GAGPOL Polyproteins 4/379 14/10654 0.0011880852972778297 0.0031565483367354675 0.0014082004370161946 7311/7316/7314/6233 4 Sindbis_virus R-HSA-3371568 Attenuation phase 4/379 14/10654 0.0011880852972778297 0.0031565483367354675 0.0014082004370161946 3306/3303/1387/2033 4 Sindbis_virus R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 4/379 14/10654 0.0011880852972778297 0.0031565483367354675 0.0014082004370161946 1017/1869/7157/1026 4 Sindbis_virus R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 4/379 14/10654 0.0011880852972778297 0.0031565483367354675 0.0014082004370161946 7157/54971/207/208 4 Sindbis_virus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 8/379 60/10654 0.0012071762296789327 0.003190164382964859 0.001423197239200426 8454/1017/7311/5698/7316/1026/7314/6233 8 Sindbis_virus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 8/379 60/10654 0.0012071762296789327 0.003190164382964859 0.001423197239200426 8454/7311/5698/7316/5970/9040/7314/6233 8 Sindbis_virus R-HSA-9616222 Transcriptional regulation of granulopoiesis 10/379 90/10654 0.0013060390223836925 0.0034422464659102105 0.001535656185333569 1017/5914/688/2033/1869/6886/4602/1050/1026/4609 10 Sindbis_virus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 6/379 35/10654 0.00131758919295352 0.0034634771623791465 0.0015451276309939367 9883/9972/23636/8021/10482/4927 6 Sindbis_virus R-HSA-8940973 RUNX2 regulates osteoblast differentiation 5/379 24/10654 0.0013479704119136852 0.003533964757159953 0.0015765735811855968 25/8841/10413/5594/3280 5 Sindbis_virus R-HSA-73772 RNA Polymerase I Promoter Escape 10/379 91/10654 0.0014219489303582845 0.0037180775461347227 0.0016587100423565602 404672/2967/902/2965/2068/2071/1022/4331/2966/2968 10 Sindbis_virus R-HSA-8986944 Transcriptional Regulation by MECP2 8/379 62/10654 0.00149982930362088 0.003911396947074453 0.0017449537604453452 8841/4343/5728/28996/816/3066/3065/817 8 Sindbis_virus R-HSA-177243 Interactions of Rev with host cellular proteins 6/379 36/10654 0.0015344885002464364 0.0039912811121895495 0.001780591711848331 9883/9972/23636/8021/4927/4869 6 Sindbis_virus R-HSA-111447 Activation of BAD and translocation to mitochondria 4/379 15/10654 0.001575011344812721 0.004054120110933523 0.0018086254677275265 2810/596/207/208 4 Sindbis_virus R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 4/379 15/10654 0.001575011344812721 0.004054120110933523 0.0018086254677275265 7311/7316/7314/6233 4 Sindbis_virus R-HSA-844456 The NLRP3 inflammasome 4/379 15/10654 0.001575011344812721 0.004054120110933523 0.0018086254677275265 834/10628/4790/5970 4 Sindbis_virus R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 4/379 15/10654 0.001575011344812721 0.004054120110933523 0.0018086254677275265 7311/7316/7314/6233 4 Sindbis_virus R-HSA-177929 Signaling by EGFR 7/379 49/10654 0.001612854650349687 0.004140774503877046 0.0018472837555136856 5295/7311/1956/3845/7316/7314/6233 7 Sindbis_virus R-HSA-1912408 Pre-NOTCH Transcription and Translation 10/379 93/10654 0.001678878867611257 0.00429914459380557 0.0019179358748721011 22938/8850/3725/51548/1387/4343/2033/1869/4851/7157 10 Sindbis_virus R-HSA-5683057 MAPK family signaling cascades 21/379 294/10654 0.0018858100266903105 0.004816592104252828 0.00214877973741164 409/2308/7311/3725/1956/5698/4343/8452/2335/3845/7316/673/9978/5747/816/817/5245/5594/4609/7314/6233 21 Swinepox_virus R-HSA-449147 Signaling by Interleukins 48/74 461/10654 7.283995332729143e-48 2.8116221984334495e-45 2.0701881471967045e-45 5601/3565/3934/50616/9235/3605/7124/3627/3586/836/3576/7422/4791/3606/4615/3594/3554/3553/834/3552/6352/7412/3458/1437/10068/8807/8809/3725/6347/4790/4609/27178/6774/3569/4318/3596/5599/5970/5595/3567/3383/356/2919/3600/3558/90865/6775/207 48 Swinepox_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 20/74 108/10654 7.861082106279282e-24 1.5171888465119016e-21 1.1171011414186351e-21 3565/3934/3605/7124/3586/3576/7422/3606/3553/3552/7412/6347/4609/6774/3569/4318/3596/3383/356/207 20 Swinepox_virus R-HSA-6783783 Interleukin-10 signaling 15/74 47/10654 5.92375008288003e-22 7.621891773305637e-20 5.61197376272845e-20 7124/3627/3586/3576/3606/3554/3553/3552/6352/1437/6347/6774/3569/3383/2919 15 Swinepox_virus R-HSA-446652 Interleukin-1 family signaling 18/74 140/10654 1.7408613200703266e-18 1.2499571807859175e-16 9.203393477289277e-17 3565/4791/3606/4615/3554/3553/834/3552/10068/8807/8809/4790/27178/6774/3596/5599/5970/90865 18 Swinepox_virus R-HSA-5260271 Diseases of Immune System 11/74 24/10654 1.9429386229832914e-18 1.2499571807859175e-16 9.203393477289277e-17 10333/7097/7099/4791/4615/81793/7098/7100/4790/5970/7096 11 Swinepox_virus R-HSA-5602358 Diseases associated with the TLR signaling cascade 11/74 24/10654 1.9429386229832914e-18 1.2499571807859175e-16 9.203393477289277e-17 10333/7097/7099/4791/4615/81793/7098/7100/4790/5970/7096 11 Swinepox_virus R-HSA-168898 Toll-like Receptor Cascades 18/74 155/10654 1.131017798662086e-17 6.236755289765217e-16 4.59210234043253e-16 5601/54106/10333/7097/7099/4791/4615/81793/7098/7100/3725/51284/4790/5599/5970/7096/5595/51311 18 Swinepox_virus R-HSA-622312 Inflammasomes 10/74 20/10654 2.4301407309203366e-17 1.1725429026690623e-15 8.633394701953828e-16 4210/4791/22861/834/9447/4790/29108/5970/114548/58484 10 Swinepox_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 11/74 55/10654 7.866199987939874e-14 3.3737257726053234e-12 2.4840631540862763e-12 4210/4791/22861/834/9447/4790/29108/5970/114548/837/58484 11 Swinepox_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 12/74 92/10654 1.1645028219087915e-12 4.277524470924041e-11 3.149527153393758e-11 5601/54106/7099/4791/4615/3725/51284/4790/5599/5970/5595/51311 12 Swinepox_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 12/74 93/10654 1.3298003536551423e-12 4.277524470924041e-11 3.149527153393758e-11 5601/54106/7099/4791/4615/3725/51284/4790/5599/5970/5595/51311 12 Swinepox_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 12/74 93/10654 1.3298003536551423e-12 4.277524470924041e-11 3.149527153393758e-11 5601/54106/7099/4791/4615/3725/51284/4790/5599/5970/5595/51311 12 Swinepox_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 12/74 95/10654 1.7260029039378117e-12 4.7588365779999665e-11 3.5039156696481895e-11 5601/10333/7097/7099/4791/4615/3725/4790/5599/5970/7096/5595 12 Swinepox_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 12/74 95/10654 1.7260029039378117e-12 4.7588365779999665e-11 3.5039156696481895e-11 5601/10333/7097/7099/4791/4615/3725/4790/5599/5970/7096/5595 12 Swinepox_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 12/74 97/10654 2.226800665864682e-12 5.730300380158449e-11 4.219201261638345e-11 5601/54106/7099/4791/4615/3725/51284/4790/5599/5970/5595/51311 12 Swinepox_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 12/74 98/10654 2.5238079988587383e-12 5.7305287503498416e-11 4.219369409856715e-11 5601/10333/7097/7099/4791/4615/3725/4790/5599/5970/7096/5595 12 Swinepox_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 12/74 98/10654 2.5238079988587383e-12 5.7305287503498416e-11 4.219369409856715e-11 5601/10333/7097/7099/4791/4615/3725/4790/5599/5970/7096/5595 12 Swinepox_virus R-HSA-844456 The NLRP3 inflammasome 7/74 15/10654 3.591155198218755e-12 7.701032813957997e-11 5.6702450498190877e-11 4210/4791/834/4790/29108/5970/114548 7 Swinepox_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 12/74 129/10654 6.870077026264504e-11 1.3957103853358412e-9 1.0276569512971836e-9 5601/10333/7097/7099/4791/4615/3725/4790/5599/5970/7096/5595 12 Swinepox_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 10/74 85/10654 2.880561600306479e-10 5.054076262355914e-9 3.7212996750370786e-9 5601/4791/4615/81793/7100/3725/4790/5599/5970/5595 10 Swinepox_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 10/74 85/10654 2.880561600306479e-10 5.054076262355914e-9 3.7212996750370786e-9 5601/4791/4615/81793/7100/3725/4790/5599/5970/5595 10 Swinepox_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 10/74 85/10654 2.880561600306479e-10 5.054076262355914e-9 3.7212996750370786e-9 5601/4791/4615/81793/7100/3725/4790/5599/5970/5595 10 Swinepox_virus R-HSA-5602498 MyD88 deficiency (TLR2/4) 5/74 10/10654 3.457269382698683e-9 5.8021999205290946e-8 4.272140655966337e-8 10333/7097/7099/4615/7096 5 Swinepox_virus R-HSA-5603041 IRAK4 deficiency (TLR2/4) 5/74 11/10654 6.304115831106787e-9 1.0139119628363415e-7 7.465400326310671e-8 10333/7097/7099/4615/7096 5 Swinepox_virus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 5/74 17/10654 8.173977943603937e-8 1.2620621944924478e-6 9.292522293781319e-7 4791/4615/7098/4790/5970 5 Swinepox_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 8/74 94/10654 2.5396108075761663e-7 3.6262668861102027e-6 2.6700083426499998e-6 5601/4791/7098/3725/4790/5599/5970/5595 8 Swinepox_virus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 5/74 21/10654 2.630452663499629e-7 3.6262668861102027e-6 2.6700083426499998e-6 4791/4615/7098/4790/5970 5 Swinepox_virus R-HSA-9008059 Interleukin-37 signaling 5/74 21/10654 2.630452663499629e-7 3.6262668861102027e-6 2.6700083426499998e-6 834/10068/8809/27178/6774 5 Swinepox_virus R-HSA-166166 MyD88-independent TLR4 cascade 8/74 99/10654 3.799333979944296e-7 4.888476387528328e-6 3.5993690336314394e-6 5601/7099/4791/3725/4790/5599/5970/5595 8 Swinepox_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 8/74 99/10654 3.799333979944296e-7 4.888476387528328e-6 3.5993690336314394e-6 5601/7099/4791/3725/4790/5599/5970/5595 8 Swinepox_virus R-HSA-450341 Activation of the AP-1 family of transcription factors 4/74 10/10654 4.3634060648063977e-7 5.433144325855708e-6 4.0004062393810786e-6 5601/3725/5599/5595 4 Swinepox_virus R-HSA-451927 Interleukin-2 family signaling 6/74 44/10654 5.23416973708772e-7 6.313717245362062e-6 4.64876917438712e-6 1437/6774/3567/3600/3558/6775 6 Swinepox_virus R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 8/74 110/10654 8.555514193519409e-7 9.879566253701663e-6 7.274292032995499e-6 3576/3552/3725/4790/6774/3569/5970/5595 8 Swinepox_virus R-HSA-2559583 Cellular Senescence 10/74 195/10654 8.702208617250169e-7 9.879566253701663e-6 7.274292032995499e-6 5601/3576/3552/3725/4790/6774/3569/5599/5970/5595 10 Swinepox_virus R-HSA-1679131 Trafficking and processing of endosomal TLR 4/74 13/10654 1.4623467318823038e-6 1.6127595385901977e-5 1.1874695266412695e-5 54106/7098/51284/51311 4 Swinepox_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 4/74 15/10654 2.762510572660225e-6 2.96202522513013e-5 2.1809293994685988e-5 54106/4615/51284/51311 4 Swinepox_virus R-HSA-380108 Chemokine receptors bind chemokines 6/74 59/10654 3.0772970422811305e-6 3.210369346812206e-5 2.3637843568020068e-5 3627/3576/1236/6352/6347/2919 6 Swinepox_virus R-HSA-9020702 Interleukin-1 signaling 7/74 103/10654 6.803235095586418e-6 6.910654597095677e-5 5.0882921767543856e-5 4791/4615/3554/3553/3552/4790/5970 7 Swinepox_virus R-HSA-5686938 Regulation of TLR by endogenous ligand 4/74 19/10654 7.680916383159557e-6 7.60213775358869e-5 5.5974289431932004e-5 10333/7097/7099/7096 4 Swinepox_virus R-HSA-448424 Interleukin-17 signaling 6/74 72/10654 9.937348008971199e-6 9.589540828657207e-5 7.06074726953217e-5 5601/3605/3725/4790/5599/5595 6 Swinepox_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 5/74 53/10654 3.1207905179804234e-5 2.9381100974157153e-4 2.1633207698452234e-4 836/6774/5599/5595/207 5 Swinepox_virus R-HSA-447115 Interleukin-12 family signaling 5/74 57/10654 4.4563197665991566e-5 4.095570071207796e-4 3.015554729277625e-4 3586/3594/3458/6774/6775 5 Swinepox_virus R-HSA-73887 Death Receptor Signalling 7/74 141/10654 5.2620155600509055e-5 4.7235767585573245e-4 3.4779539809393995e-4 7124/836/4615/4790/5599/5970/356 7 Swinepox_virus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 4/74 31/10654 5.854144548441134e-5 5.135681353859722e-4 3.78138523463901e-4 5601/3725/5599/5595 4 Swinepox_virus R-HSA-2871796 FCERI mediated MAPK activation 4/74 32/10654 6.655410105945414e-5 5.708862890877621e-4 4.2034169090181576e-4 5601/3725/5599/5595 4 Swinepox_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 5/74 63/10654 7.242701729945102e-5 6.077571451649586e-4 4.4748958056869053e-4 4791/4615/7098/4790/5970 5 Swinepox_virus R-HSA-450294 MAP kinase activation 5/74 64/10654 7.814268033009215e-5 6.417675448386292e-4 4.725313256242975e-4 5601/3725/4790/5599/5595 5 Swinepox_virus R-HSA-193639 p75NTR signals via NF-kB 3/74 16/10654 1.688132752110513e-4 0.0013575400881555373 9.995522874338566e-4 4615/4790/5970 3 Swinepox_virus R-HSA-109581 Apoptosis 7/74 178/10654 2.2638255277736307e-4 0.0017833401096339213 0.0013130674382360482 7099/836/6774/5599/5595/356/207 7 Swinepox_virus R-HSA-5357801 Programmed Cell Death 7/74 181/10654 2.5081158189969383e-4 0.0019362654122656363 0.0014256658339561548 7099/836/6774/5599/5595/356/207 7 Swinepox_virus R-HSA-1236974 ER-Phagosome pathway 5/74 83/10654 2.686359877496812e-4 0.002033205711203469 0.0014970426561901739 10333/7097/7099/4615/7096 5 Swinepox_virus R-HSA-9020591 Interleukin-12 signaling 4/74 47/10654 3.051394139890244e-4 0.0022650733423031427 0.0016677660278752349 3586/3594/3458/6775 4 Swinepox_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 6/74 134/10654 3.2528762654842854e-4 0.0023690759216545925 0.0017443427838743934 5601/3725/4790/5599/5970/5595 6 Swinepox_virus R-HSA-2262752 Cellular responses to stress 11/74 479/10654 4.338061612563492e-4 0.0031009107082398293 0.0022831903224018383 5601/3576/7422/3552/3725/4790/6774/3569/5599/5970/5595 11 Swinepox_virus R-HSA-8953897 Cellular responses to external stimuli 11/74 493/10654 5.529207800589995e-4 0.003812087919366986 0.0028068277562833008 5601/3576/7422/3552/3725/4790/6774/3569/5599/5970/5595 11 Swinepox_virus R-HSA-193704 p75 NTR receptor-mediated signalling 5/74 97/10654 5.530490245713762e-4 0.003812087919366986 0.0028068277562833008 836/4615/4790/5599/5970 5 Swinepox_virus R-HSA-933542 TRAF6 mediated NF-kB activation 3/74 24/10654 5.862614841967044e-4 0.003970121629823296 0.002923187455828443 4791/4790/5970 3 Swinepox_virus R-HSA-1236975 Antigen processing-Cross presentation 5/74 99/10654 6.072234801702924e-4 0.004041176954236773 0.0029755052567328306 10333/7097/7099/4615/7096 5 Swinepox_virus R-HSA-8854691 Interleukin-20 family signaling 3/74 25/10654 6.628940405056558e-4 0.004280027056288054 0.0031513697987395 50616/6774/6775 3 Swinepox_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 5/74 101/10654 6.652891797338943e-4 0.004280027056288054 0.0031513697987395 4791/3553/4790/29108/5970 5 Tomato_spotted_wilt_virus R-HSA-5696398 Nucleotide Excision Repair 93/197 111/10654 8.013324129321823e-153 4.864087746498346e-150 1.568924513740904e-150 5982/7316/10450/91603/9318/5981/7507/5436/10038/404672/9978/8178/7329/142/5433/7336/5886/8533/27339/57654/54107/10714/50813/6119/7311/7874/902/2068/5111/6118/5438/9557/56655/5426/3978/5439/5887/1642/5983/9716/6117/10987/1643/5431/2965/7341/5985/10920/7508/2966/2967/7314/2071/5430/2073/6233/56949/2072/51138/5424/2033/57804/5437/8451/1022/6612/6917/5432/2067/8450/4331/8554/51426/6613/10980/5441/2873/5434/10401/5440/7515/5435/5427/7334/3150/64708/1161/5984/3980/54778/1069/5425/2968 93 Tomato_spotted_wilt_virus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 76/197 79/10654 1.0021071863063489e-134 3.041395310439769e-132 9.810101929104258e-133 5982/7316/10450/91603/9318/5981/7507/5436/404672/9978/8178/5433/8533/27339/57654/54107/10714/50813/6119/7311/7874/902/2068/5111/6118/5438/56655/5426/3978/5439/1642/5983/9716/6117/10987/5431/2965/5985/10920/2966/2967/7314/2071/5430/2073/6233/56949/2072/51138/5424/2033/57804/5437/8451/1022/6917/5432/2067/8450/4331/51426/10980/5441/2873/5434/5440/7515/5435/5427/3150/64708/1161/5984/3980/5425/2968 76 Tomato_spotted_wilt_virus R-HSA-674695 RNA Polymerase II Pre-transcription Events 76/197 84/10654 5.219438991242778e-129 1.0560664892281222e-126 3.4063707100742348e-127 83860/6883/6879/9150/2962/6908/7936/5436/404672/8178/5433/6873/6829/6830/9646/1025/905/6884/79577/23168/6872/51497/55677/6827/902/6875/6882/4298/2068/2960/4300/2961/5438/55840/54623/5439/6877/80349/6749/2959/138474/5431/2965/7469/2957/2958/8148/6881/2966/2967/85403/2071/11198/54457/2963/5430/27125/51616/5437/1022/8812/123169/6917/5432/6878/4331/25920/6874/5441/5434/5440/22916/5435/904/4686/2968 76 Tomato_spotted_wilt_virus R-HSA-6782135 Dual incision in TC-NER 63/197 66/10654 4.914383117851546e-110 6.1414397367944205e-108 1.980937815041641e-108 5982/7316/10450/91603/5981/7507/5436/404672/9978/5433/27339/57654/54107/10714/6119/7311/7874/902/2068/5111/6118/5438/56655/5426/5439/1642/5983/9716/6117/5431/2965/5985/2966/2967/7314/2071/5430/2073/6233/56949/2072/5424/2033/57804/5437/8451/1022/6917/5432/2067/8450/4331/51426/5441/5434/5440/5435/5427/3150/1161/5984/5425/2968 63 Tomato_spotted_wilt_virus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 69/197 84/10654 5.0588465706708567e-110 6.1414397367944205e-108 1.980937815041641e-108 5982/7316/9318/5981/7507/10038/404672/9978/7329/142/7336/5886/8533/54107/10714/50813/6119/7311/902/2068/5111/6118/9557/56655/5426/3978/5887/1642/5983/6117/10987/1643/2965/7341/5985/10920/7508/2966/2967/7314/2071/2073/6233/2072/51138/5424/57804/8451/1022/6612/2067/8450/4331/8554/51426/6613/10980/2873/10401/7515/5427/7334/64708/5984/3980/54778/1069/5425/2968 69 Tomato_spotted_wilt_virus R-HSA-73894 DNA Repair 105/197 334/10654 2.206995514096979e-109 2.232743795094777e-107 7.201774835474354e-108 5982/7316/10450/91603/672/9318/5981/7507/5436/10038/404672/9978/8178/7329/142/5433/7706/9656/7336/5886/8533/7158/27339/57654/54107/10714/50813/6119/7311/7874/902/2068/5888/5111/6118/5438/9557/2177/56655/5426/3978/5439/1111/5887/1642/5983/9716/6117/10987/1643/5431/2965/7341/5985/10920/7508/2966/2967/7314/2071/545/5430/2073/6233/56949/7157/2072/51138/5424/2033/57804/5437/2237/8451/1022/6612/472/6917/55215/5432/2067/8450/4331/8554/51426/6613/10980/5441/2873/5434/10401/5440/7515/5435/5427/7334/3150/64708/1161/5984/3980/54778/1069/5425/2968 105 Tomato_spotted_wilt_virus R-HSA-167172 Transcription of the HIV genome 65/197 73/10654 2.1576091138643588e-108 1.870955331593808e-106 6.034816468853696e-107 83860/6883/8732/6879/9150/2962/6908/7936/5436/404672/8178/5433/6873/6829/1025/905/6884/6872/51497/6827/902/6875/6882/2068/2960/2961/5438/5439/6877/6749/2959/138474/5431/2965/7469/2957/2958/8148/6881/2966/2967/2071/11198/54457/2963/5430/51616/5437/8731/1022/8812/6917/5432/6878/4331/25920/6874/5441/5434/5440/22916/5435/904/4686/2968 65 Tomato_spotted_wilt_virus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 62/197 65/10654 3.679534886070048e-108 2.7918470948056487e-106 9.005177484329328e-107 5982/7316/10450/91603/5981/5436/404672/9978/5433/27339/57654/54107/10714/6119/7311/7874/902/2068/5111/6118/5438/56655/5426/3978/5439/1642/5983/9716/6117/5431/2965/5985/2966/2967/7314/2071/5430/6233/56949/5424/2033/57804/5437/8451/1022/6917/5432/8450/4331/51426/5441/5434/5440/7515/5435/5427/3150/1161/5984/3980/5425/2968 62 Tomato_spotted_wilt_virus R-HSA-112382 Formation of RNA Pol II elongation complex 54/197 61/10654 3.857818414690826e-89 2.3416957777173313e-87 7.553202369815722e-88 9150/2962/7936/5436/404672/8178/5433/6829/6830/9646/1025/905/79577/23168/51497/55677/6827/902/4298/2068/4300/5438/55840/54623/5439/80349/6749/5431/2965/7469/2966/2967/85403/2071/11198/2963/5430/27125/5437/1022/8812/123169/6917/5432/4331/25920/5441/5434/5440/22916/5435/904/4686/2968 54 Tomato_spotted_wilt_virus R-HSA-75955 RNA Polymerase II Transcription Elongation 54/197 61/10654 3.857818414690826e-89 2.3416957777173313e-87 7.553202369815722e-88 9150/2962/7936/5436/404672/8178/5433/6829/6830/9646/1025/905/79577/23168/51497/55677/6827/902/4298/2068/4300/5438/55840/54623/5439/80349/6749/5431/2965/7469/2966/2967/85403/2071/11198/2963/5430/27125/5437/1022/8812/123169/6917/5432/4331/25920/5441/5434/5440/22916/5435/904/4686/2968 54 Tomato_spotted_wilt_virus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 51/197 54/10654 9.036848509176112e-88 4.9866973136999085e-86 1.6084725576141216e-086 7316/10450/91603/9318/7507/5436/404672/9978/5433/8533/27339/57654/50813/7311/7874/902/2068/5438/5439/1642/9716/10987/5431/2965/10920/2966/2967/7314/2071/5430/6233/56949/51138/2033/5437/8451/1022/6917/5432/8450/4331/10980/5441/2873/5434/5440/5435/3150/64708/1161/2968 51 Tomato_spotted_wilt_virus R-HSA-162587 HIV Life Cycle 71/197 152/10654 6.0419296619139844e-86 3.0562094206514907e-84 9.857885237859659e-85 83860/7316/6883/8732/6879/9150/2962/6908/7936/5436/404672/8178/5433/6873/6829/1025/905/6884/6872/51497/7311/6827/902/6875/6882/2068/2960/2961/5438/3978/5439/6877/6749/2959/138474/5431/2965/7469/2957/2958/8148/6881/2966/2967/7314/2071/11198/54457/2963/5430/6233/51616/5437/2237/8731/1022/8812/6917/5432/6878/4331/25920/6874/5441/5434/5440/22916/5435/904/4686/2968 71 Tomato_spotted_wilt_virus R-HSA-162599 Late Phase of HIV Life Cycle 69/197 139/10654 8.26441975669404e-86 3.858848301779448e-84 1.2446818418988594e-84 83860/7316/6883/8732/6879/9150/2962/6908/7936/5436/404672/8178/5433/6873/6829/1025/905/6884/6872/51497/7311/6827/902/6875/6882/2068/2960/2961/5438/5439/6877/6749/2959/138474/5431/2965/7469/2957/2958/8148/6881/2966/2967/7314/2071/11198/54457/2963/5430/6233/51616/5437/8731/1022/8812/6917/5432/6878/4331/25920/6874/5441/5434/5440/22916/5435/904/4686/2968 69 Tomato_spotted_wilt_virus R-HSA-167161 HIV Transcription Initiation 46/197 47/10654 3.214707464041289e-81 1.0270144371963487e-79 3.31266253912288e-80 83860/6883/6879/2962/6908/5436/404672/5433/6873/6884/6872/902/6875/6882/2068/2960/2961/5438/5439/6877/2959/138474/5431/2965/2957/2958/8148/6881/2966/2967/2071/54457/2963/5430/51616/5437/1022/5432/6878/4331/6874/5441/5434/5440/5435/2968 46 Tomato_spotted_wilt_virus R-HSA-167162 RNA Polymerase II HIV Promoter Escape 46/197 47/10654 3.214707464041289e-81 1.0270144371963487e-79 3.31266253912288e-80 83860/6883/6879/2962/6908/5436/404672/5433/6873/6884/6872/902/6875/6882/2068/2960/2961/5438/5439/6877/2959/138474/5431/2965/2957/2958/8148/6881/2966/2967/2071/54457/2963/5430/51616/5437/1022/5432/6878/4331/6874/5441/5434/5440/5435/2968 46 Tomato_spotted_wilt_virus R-HSA-73776 RNA Polymerase II Promoter Escape 46/197 47/10654 3.214707464041289e-81 1.0270144371963487e-79 3.31266253912288e-80 83860/6883/6879/2962/6908/5436/404672/5433/6873/6884/6872/902/6875/6882/2068/2960/2961/5438/5439/6877/2959/138474/5431/2965/2957/2958/8148/6881/2966/2967/2071/54457/2963/5430/51616/5437/1022/5432/6878/4331/6874/5441/5434/5440/5435/2968 46 Tomato_spotted_wilt_virus R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 46/197 47/10654 3.214707464041289e-81 1.0270144371963487e-79 3.31266253912288e-80 83860/6883/6879/2962/6908/5436/404672/5433/6873/6884/6872/902/6875/6882/2068/2960/2961/5438/5439/6877/2959/138474/5431/2965/2957/2958/8148/6881/2966/2967/2071/54457/2963/5430/51616/5437/1022/5432/6878/4331/6874/5441/5434/5440/5435/2968 46 Tomato_spotted_wilt_virus R-HSA-75953 RNA Polymerase II Transcription Initiation 46/197 47/10654 3.214707464041289e-81 1.0270144371963487e-79 3.31266253912288e-80 83860/6883/6879/2962/6908/5436/404672/5433/6873/6884/6872/902/6875/6882/2068/2960/2961/5438/5439/6877/2959/138474/5431/2965/2957/2958/8148/6881/2966/2967/2071/54457/2963/5430/51616/5437/1022/5432/6878/4331/6874/5441/5434/5440/5435/2968 46 Tomato_spotted_wilt_virus R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 46/197 47/10654 3.214707464041289e-81 1.0270144371963487e-79 3.31266253912288e-80 83860/6883/6879/2962/6908/5436/404672/5433/6873/6884/6872/902/6875/6882/2068/2960/2961/5438/5439/6877/2959/138474/5431/2965/2957/2958/8148/6881/2966/2967/2071/54457/2963/5430/51616/5437/1022/5432/6878/4331/6874/5441/5434/5440/5435/2968 46 Tomato_spotted_wilt_virus R-HSA-5696395 Formation of Incision Complex in GG-NER 42/197 43/10654 6.713060290443423e-74 2.037413798149579e-72 6.571732705381456e-73 7316/7507/10038/404672/9978/7329/142/7336/5886/6119/7311/902/2068/6118/9557/5887/1642/6117/1643/2965/7341/7508/2966/2967/7314/2071/2073/6233/2072/8451/1022/6612/2067/8450/4331/8554/6613/10401/7334/54778/1069/2968 42 Tomato_spotted_wilt_virus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 49/197 65/10654 1.0196848119347227e-73 2.9473746706875083e-72 9.506835840594407e-73 9150/672/2962/7936/5436/404672/8178/5433/6829/9656/1025/905/51497/6827/902/2068/5438/2177/5439/1111/6749/1643/5431/2965/7469/51755/2966/2967/2071/11198/2963/545/5430/7157/5437/1022/8812/472/6917/55215/5432/4331/25920/5441/5434/5440/5435/904/2968 49 Tomato_spotted_wilt_virus R-HSA-5696400 Dual Incision in GG-NER 41/197 41/10654 1.0774722915425714e-73 2.972844004392458e-72 9.588987857747286e-73 5982/7316/5981/7507/10038/404672/9978/142/54107/10714/6119/7311/2068/5111/6118/9557/56655/5426/1642/5983/6117/1643/2965/5985/2966/2967/7314/2071/2073/6233/2072/5424/57804/8451/2067/8450/51426/5427/5984/5425/2968 41 Tomato_spotted_wilt_virus R-HSA-162906 HIV Infection 73/197 233/10654 5.887605478628414e-73 1.5538158806641074e-71 5.011874686612746e-72 83860/7316/6883/8732/6879/9150/2962/6908/7936/5436/404672/9978/8178/5433/6873/6829/1025/905/6884/6872/51497/7311/6827/902/6875/6882/2068/2960/2961/5438/3978/5439/6877/6749/2959/138474/5431/2965/7469/5701/2957/2958/8148/6881/2966/2967/7314/2071/11198/54457/2963/5430/6233/51616/5437/2237/8731/1022/8812/6917/5432/6878/4331/25920/6874/5441/5434/5440/22916/5435/904/4686/2968 73 Tomato_spotted_wilt_virus R-HSA-3700989 Transcriptional Regulation by TP53 82/197 365/10654 1.6432262538719113e-69 4.155993067084376e-68 1.3405266807902436e-68 5982/83860/7316/6883/6879/9150/672/2962/6908/7936/5436/404672/8178/5433/6873/1869/6829/9656/1025/905/6884/6872/51497/6119/7311/7874/6827/902/6875/6882/2068/5111/6118/5438/2177/5439/1111/6877/5983/6749/6117/1643/138474/5431/2965/7469/5985/8148/6881/51755/2966/2967/7314/2071/11198/54457/2963/545/5430/6233/7157/51616/2033/5437/1022/8812/7862/472/6917/55215/5432/6878/4331/25920/6874/5441/5434/5440/5435/904/5984/2968 82 Tomato_spotted_wilt_virus R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 41/197 48/10654 7.169791870075931e-66 1.7408254660544364e-64 5.6150791066699926e-65 9150/2962/7936/5436/404672/8178/5433/6829/1025/905/51497/6827/902/2068/5438/5439/6749/5431/2965/7469/2966/2967/2071/11198/2963/5430/5437/1022/8812/6917/5432/4331/25920/5441/5434/5440/22916/5435/904/4686/2968 41 Tomato_spotted_wilt_virus R-HSA-167169 HIV Transcription Elongation 39/197 46/10654 2.3645544677974467e-62 5.1260162926894644e-61 1.6534102669561096e-61 9150/2962/7936/5436/404672/8178/5433/6829/1025/51497/6827/902/2068/5438/5439/6749/5431/2965/7469/2966/2967/2071/11198/2963/5430/5437/1022/6917/5432/4331/25920/5441/5434/5440/22916/5435/904/4686/2968 39 Tomato_spotted_wilt_virus R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 39/197 46/10654 2.3645544677974467e-62 5.1260162926894644e-61 1.6534102669561096e-61 9150/2962/7936/5436/404672/8178/5433/6829/1025/51497/6827/902/2068/5438/5439/6749/5431/2965/7469/2966/2967/2071/11198/2963/5430/5437/1022/6917/5432/4331/25920/5441/5434/5440/22916/5435/904/4686/2968 39 Tomato_spotted_wilt_virus R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 39/197 46/10654 2.3645544677974467e-62 5.1260162926894644e-61 1.6534102669561096e-61 9150/2962/7936/5436/404672/8178/5433/6829/1025/51497/6827/902/2068/5438/5439/6749/5431/2965/7469/2966/2967/2071/11198/2963/5430/5437/1022/6917/5432/4331/25920/5441/5434/5440/22916/5435/904/4686/2968 39 Tomato_spotted_wilt_virus R-HSA-113418 Formation of the Early Elongation Complex 33/197 33/10654 3.954922682727368e-59 8.002126894718375e-58 2.581107435043124e-58 9150/2962/7936/5436/404672/5433/6829/51497/6827/902/2068/5438/5439/5431/2965/7469/2966/2967/2071/2963/5430/5437/1022/5432/4331/25920/5441/5434/5440/22916/5435/4686/2968 33 Tomato_spotted_wilt_virus R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 33/197 33/10654 3.954922682727368e-59 8.002126894718375e-58 2.581107435043124e-58 9150/2962/7936/5436/404672/5433/6829/51497/6827/902/2068/5438/5439/5431/2965/7469/2966/2967/2071/2963/5430/5437/1022/5432/4331/25920/5441/5434/5440/22916/5435/4686/2968 33 Tomato_spotted_wilt_virus R-HSA-5663205 Infectious disease 75/197 383/10654 2.984405012463775e-58 5.84365755666294e-57 1.8848873762929105e-57 83860/7316/6883/8732/6879/9150/2962/6908/7936/3839/5436/404672/9978/8178/5433/6873/6829/1025/905/6884/6872/51497/7311/6827/902/6875/6882/2068/2960/2961/5438/3978/5439/6877/6749/2959/138474/5431/2965/7469/5701/2957/2958/11224/8148/6881/2966/2967/7314/2071/11198/54457/2963/5430/6233/51616/5437/2237/8731/1022/8812/6917/5432/6878/4331/25920/6874/5441/5434/5440/22916/5435/904/4686/2968 75 Tomato_spotted_wilt_virus R-HSA-72086 mRNA Capping 29/197 29/10654 6.555271623860867e-52 1.2434530861511082e-50 4.010791190914873e-51 8732/2962/5436/404672/5433/6829/902/2068/5438/5439/5431/2965/2966/2967/2071/2963/5430/5437/8731/1022/5432/4331/5441/5434/5440/22916/5435/4686/2968 29 Tomato_spotted_wilt_virus R-HSA-73863 RNA Polymerase I Transcription Termination 30/197 32/10654 4.9858321364384384e-51 9.1709094146004e-50 2.9581013632457723e-50 25885/9013/6908/404672/79101/9014/902/84172/2068/9015/7343/2965/2966/2967/2071/9533/10849/7270/5437/1022/64425/4331/30834/5441/221830/5434/5440/5435/51082/2968 30 Tomato_spotted_wilt_virus R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 27/197 27/10654 2.5765321025268724e-48 4.46844281781089e-47 1.4413081836691676e-47 8732/2962/5436/404672/5433/6829/902/2068/5438/5439/5431/2965/2966/2967/2071/2963/5430/5437/8731/1022/5432/4331/5441/5434/5440/5435/2968 27 Tomato_spotted_wilt_virus R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 27/197 27/10654 2.5765321025268724e-48 4.46844281781089e-47 1.4413081836691676e-47 8732/2962/5436/404672/5433/6829/902/2068/5438/5439/5431/2965/2966/2967/2071/2963/5430/5437/8731/1022/5432/4331/5441/5434/5440/5435/2968 27 Tomato_spotted_wilt_virus R-HSA-167287 HIV elongation arrest and recovery 29/197 36/10654 4.9127065694514485e-45 8.059494290964945e-44 2.5996114421563854e-44 9150/2962/7936/5436/8178/5433/6829/1025/905/51497/6827/5438/5439/6749/5431/7469/11198/2963/5430/5437/8812/6917/5432/25920/5441/5434/5440/5435/904 29 Tomato_spotted_wilt_virus R-HSA-167290 Pausing and recovery of HIV elongation 29/197 36/10654 4.9127065694514485e-45 8.059494290964945e-44 2.5996114421563854e-44 9150/2962/7936/5436/8178/5433/6829/1025/905/51497/6827/5438/5439/6749/5431/7469/11198/2963/5430/5437/8812/6917/5432/25920/5441/5434/5440/5435/904 29 Tomato_spotted_wilt_virus R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 25/197 25/10654 9.895892148794161e-45 1.5807385616626463e-43 5.098714514337158e-44 5982/7316/5981/54107/10714/6119/7311/5111/6118/56655/5426/3978/5983/6117/5985/7314/6233/5424/57804/51426/7515/5427/5984/3980/5425 25 Tomato_spotted_wilt_virus R-HSA-73762 RNA Polymerase I Transcription Initiation 31/197 47/10654 1.918534764103993e-43 2.986027184131086e-42 9.631510556635431e-43 25885/9013/6908/404672/79101/9014/902/84172/2068/9015/7343/2965/2966/2967/2071/9533/10849/54700/7270/5437/1022/64425/4331/30834/5441/221830/5434/5440/5435/51082/2968 31 Tomato_spotted_wilt_virus R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 27/197 34/10654 1.243129258207367e-41 1.8404377066631018e-40 5.936381053313742e-41 9150/2962/7936/5436/8178/5433/6829/1025/51497/6827/5438/5439/6749/5431/7469/11198/2963/5430/5437/6917/5432/25920/5441/5434/5440/5435/904 27 Tomato_spotted_wilt_virus R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 27/197 34/10654 1.243129258207367e-41 1.8404377066631018e-40 5.936381053313742e-41 9150/2962/7936/5436/8178/5433/6829/1025/51497/6827/5438/5439/6749/5431/7469/11198/2963/5430/5437/6917/5432/25920/5441/5434/5440/5435/904 27 Tomato_spotted_wilt_virus R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 23/197 23/10654 3.715069858752306e-41 5.369160486339642e-40 1.7318370770123532e-40 9150/2962/7936/5436/5433/6829/51497/6827/5438/5439/5431/7469/2963/5430/5437/5432/25920/5441/5434/5440/22916/5435/4686 23 Tomato_spotted_wilt_virus R-HSA-6807505 RNA polymerase II transcribes snRNA genes 34/197 74/10654 4.593990079143016e-40 6.485004600092583e-39 2.0917555807113854e-39 2962/6908/5436/8178/5433/6829/1025/905/6884/6827/6882/2960/2961/5438/5439/6877/2959/5431/2957/2958/2963/5430/5437/1022/8812/5432/6878/5441/5434/5440/22916/5435/904/4686 34 Tomato_spotted_wilt_virus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 25/197 30/10654 1.3038580123437479e-39 1.7987313943014885e-38 5.801856227175529e-39 5982/7316/5981/9978/54107/10714/6119/7311/5111/6118/56655/5426/1642/5983/6117/5985/7314/6233/5424/57804/8451/8450/5427/5984/5425 25 Tomato_spotted_wilt_virus R-HSA-5693538 Homology Directed Repair 41/197 138/10654 5.668629956836108e-39 7.646351963998929e-38 2.466351279465535e-38 5982/7316/672/5981/10038/7329/142/9656/7336/7158/54107/10714/6119/7311/5888/5111/6118/56655/5426/1111/5983/6117/7341/5985/7314/545/6233/2072/5424/57804/2237/472/2067/51426/6613/7515/5427/7334/5984/3980/5425 41 Tomato_spotted_wilt_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 35/197 92/10654 1.1855580440673532e-37 1.5644211581497465e-36 5.046082292826721e-37 5982/83860/7316/6883/6879/672/6908/6873/6884/6872/6119/7311/6875/6882/6118/1111/6877/5983/6749/6117/138474/5985/8148/6881/7314/11198/54457/545/6233/7157/51616/472/6878/6874/5984 35 Tomato_spotted_wilt_virus R-HSA-5693532 DNA Double-Strand Break Repair 42/197 166/10654 1.1238292846336037e-36 1.4514135654736114e-35 4.681573279772683e-36 5982/7316/672/5981/10038/7329/142/9656/7336/7158/54107/10714/6119/7311/5888/5111/6118/56655/5426/1111/5983/6117/7341/5985/7314/545/6233/7157/2072/5424/57804/2237/472/2067/51426/6613/7515/5427/7334/5984/3980/5425 42 Tomato_spotted_wilt_virus R-HSA-73893 DNA Damage Bypass 27/197 48/10654 4.1470121422282335e-35 5.244242438192787e-34 1.6915444264352006e-34 5982/7316/5981/9978/7706/54107/10714/6119/7311/5111/6118/56655/5426/1642/5983/6117/5985/7314/6233/5424/57804/8451/8450/51426/5427/5984/5425 27 Tomato_spotted_wilt_virus R-HSA-5656169 Termination of translesion DNA synthesis 23/197 32/10654 9.03798479012175e-34 1.1196034219599802e-32 3.611310786171097e-33 5982/7316/5981/7706/54107/10714/6119/7311/5111/6118/56655/5426/5983/6117/5985/7314/6233/5424/57804/51426/5427/5984/5425 23 Tomato_spotted_wilt_virus R-HSA-5696394 DNA Damage Recognition in GG-NER 24/197 38/10654 4.7158927656442436e-33 5.725093817492111e-32 1.8466443250733248e-32 7316/9318/10038/9978/142/5886/8533/50813/7311/5887/1642/10987/1643/10920/7508/7314/6233/51138/8451/8450/10980/2873/64708/1069 24 Tomato_spotted_wilt_virus R-HSA-110373 Resolution of AP sites via the multiple-nucleotide patch replacement pathway 21/197 26/10654 8.283122149425542e-33 9.858539499414322e-32 3.1798982864667716e-32 5982/5981/10038/142/54107/10714/6119/5111/6118/56655/5426/3978/5983/6117/5985/5424/57804/2237/5427/5984/5425 21 Tomato_spotted_wilt_virus R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 36/197 132/10654 1.0348415083174106e-32 1.2079784529782082e-31 3.896366812693085e-32 5982/7316/672/5981/7329/9656/7336/7158/54107/10714/6119/7311/5888/5111/6118/56655/5426/1111/5983/6117/7341/5985/7314/545/6233/2072/5424/57804/472/2067/51426/6613/5427/7334/5984/5425 36 Tomato_spotted_wilt_virus R-HSA-5633007 Regulation of TP53 Activity 38/197 160/10654 4.9180579158014107e-32 5.632568216776333e-31 1.8167999450626861e-31 5982/83860/7316/6883/6879/672/6908/6873/6884/6872/6119/7311/7874/6875/6882/6118/1111/6877/5983/6749/6117/138474/5985/8148/6881/7314/11198/54457/545/6233/7157/51616/2033/7862/472/6878/6874/5984 38 Tomato_spotted_wilt_virus R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 19/197 21/10654 9.954628467856734e-32 1.1189739777757476e-30 3.6092804971176468e-31 5982/5981/54107/10714/6119/5111/6118/56655/5426/3978/5983/6117/5985/5424/57804/2237/5427/5984/5425 19 Tomato_spotted_wilt_virus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 23/197 39/10654 1.087752385589878e-30 1.179045889380457e-29 3.8030440548819045e-30 5982/7316/5981/7706/54107/10714/6119/7311/5111/6118/56655/5426/5983/6117/5985/7314/6233/5424/57804/51426/5427/5984/5425 23 Tomato_spotted_wilt_virus R-HSA-73933 Resolution of Abasic Sites (AP sites) 23/197 39/10654 1.087752385589878e-30 1.179045889380457e-29 3.8030440548819045e-30 5982/5981/10038/142/54107/10714/6119/5111/6118/56655/5426/3978/5983/6117/5985/5424/57804/2237/7515/5427/5984/3980/5425 23 Tomato_spotted_wilt_virus R-HSA-73772 RNA Polymerase I Promoter Escape 30/197 91/10654 4.077272768467952e-30 4.3419378429123634e-29 1.400503665623341e-29 25885/9013/6908/404672/79101/9014/902/84172/2068/9015/7343/2965/2966/2967/2071/9533/10849/54700/5437/1022/64425/4331/30834/5441/221830/5434/5440/5435/51082/2968 30 Tomato_spotted_wilt_virus R-HSA-5685942 HDR through Homologous Recombination (HRR) 27/197 67/10654 5.674430651223899e-30 5.938585181539494e-29 1.9155065356218607e-29 5982/7316/672/5981/54107/10714/6119/7311/5888/5111/6118/56655/5426/1111/5983/6117/5985/7314/545/6233/5424/57804/472/51426/5427/5984/5425 27 Tomato_spotted_wilt_virus R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 19/197 24/10654 1.9202144522581422e-29 1.975542665289309e-28 6.372165711329428e-29 5982/5981/54107/10714/6119/5111/6118/56655/5426/3978/5983/6117/5985/5424/57804/2237/5427/5984/5425 19 Tomato_spotted_wilt_virus R-HSA-73854 RNA Polymerase I Promoter Clearance 31/197 110/10654 1.0503709211818657e-28 1.0626252485956541e-27 3.4275261638566144e-28 25885/9013/6908/404672/79101/9014/902/84172/2068/9015/7343/2965/2966/2967/2071/9533/10849/54700/7270/5437/1022/64425/4331/30834/5441/221830/5434/5440/5435/51082/2968 31 Tomato_spotted_wilt_virus R-HSA-73864 RNA Polymerase I Transcription 31/197 112/10654 1.9542433333205269e-28 1.9446323005337048e-27 6.27246350297874e-28 25885/9013/6908/404672/79101/9014/902/84172/2068/9015/7343/2965/2966/2967/2071/9533/10849/54700/7270/5437/1022/64425/4331/30834/5441/221830/5434/5440/5435/51082/2968 31 Tomato_spotted_wilt_virus R-HSA-427413 NoRC negatively regulates rRNA expression 30/197 107/10654 1.0106236156334442e-27 9.894331204669366e-27 3.191442996737192e-27 25885/9013/6908/404672/79101/9014/902/84172/2068/9015/7343/2965/2966/2967/2071/9533/10849/7270/5437/1022/64425/4331/30834/5441/221830/5434/5440/5435/51082/2968 30 Tomato_spotted_wilt_virus R-HSA-5250941 Negative epigenetic regulation of rRNA expression 30/197 110/10654 2.5347287362102314e-27 2.442191020443826e-26 7.877352463410244e-27 25885/9013/6908/404672/79101/9014/902/84172/2068/9015/7343/2965/2966/2967/2071/9533/10849/7270/5437/1022/64425/4331/30834/5441/221830/5434/5440/5435/51082/2968 30 Tomato_spotted_wilt_virus R-HSA-180786 Extension of Telomeres 19/197 30/10654 2.241551823671189e-26 2.125971807763143e-25 6.857378934257256e-26 5982/5981/54107/10714/6119/5111/6118/56655/5426/3978/5983/6117/5985/5424/57804/2237/5427/5984/5425 19 Tomato_spotted_wilt_virus R-HSA-8851708 Signaling by FGFR2 IIIa TM 16/197 19/10654 9.325489655410369e-26 8.708572647437068e-25 2.8089734022774552e-25 2962/5436/5433/5438/5439/5431/2963/5430/5437/5432/5441/5434/5440/22916/5435/4686 16 Tomato_spotted_wilt_virus R-HSA-212165 Epigenetic regulation of gene expression 31/197 149/10654 2.641793623504797e-24 2.429649590102139e-23 7.836899744368298e-24 25885/9013/6908/404672/79101/9014/902/84172/2068/9015/7343/2965/2966/2967/2071/9533/10849/7270/2033/5437/1022/64425/4331/30834/5441/221830/5434/5440/5435/51082/2968 31 Tomato_spotted_wilt_virus R-HSA-69242 S Phase 31/197 161/10654 3.170330761655601e-23 2.8722250333208205e-22 9.264438675065859e-23 5982/7316/5981/9978/1869/54107/10714/5925/6119/7311/902/5111/6118/56655/5426/3978/5983/6117/5985/5701/4609/7314/6233/5424/57804/2237/1022/4331/5427/5984/5425 31 Tomato_spotted_wilt_virus R-HSA-69186 Lagging Strand Synthesis 15/197 20/10654 8.443938591703016e-23 7.537456948770191e-22 2.431226901016658e-22 5982/5981/10714/6119/5111/6118/3978/5983/6117/5985/5424/57804/2237/5984/5425 15 Tomato_spotted_wilt_virus R-HSA-5655862 Translesion synthesis by POLK 14/197 17/10654 2.22395220858436e-22 1.956433319725662e-21 6.310528006051732e-22 5982/7316/5981/6119/7311/5111/6118/5983/6117/5985/7314/6233/51426/5984 14 Tomato_spotted_wilt_virus R-HSA-6803529 FGFR2 alternative splicing 16/197 26/10654 4.565605624276794e-22 3.959032305622877e-21 1.2769964603240358e-21 2962/5436/5433/5438/5439/5431/2963/5430/5437/5432/5441/5434/5440/22916/5435/4686 16 Tomato_spotted_wilt_virus R-HSA-110312 Translesion synthesis by REV1 13/197 16/10654 1.059166682811941e-20 9.055129246011947e-20 2.9207561601633954e-20 5982/7316/5981/6119/7311/5111/6118/5983/6117/5985/7314/6233/5984 13 Tomato_spotted_wilt_virus R-HSA-69306 DNA Replication 26/197 127/10654 2.6073830513682484e-20 2.198168766917398e-19 7.090252157229447e-20 5982/7316/5981/9978/1869/54107/10714/6119/7311/5111/6118/56655/5426/3978/5983/6117/5985/5701/7314/6233/5424/57804/2237/5427/5984/5425 26 Tomato_spotted_wilt_virus R-HSA-73884 Base Excision Repair 23/197 92/10654 3.500839263074823e-20 2.9109718255978324e-19 9.389417490006013e-20 5982/5981/10038/142/54107/10714/6119/5111/6118/56655/5426/3978/5983/6117/5985/5424/57804/2237/7515/5427/5984/3980/5425 23 Tomato_spotted_wilt_virus R-HSA-5656121 Translesion synthesis by POLI 13/197 17/10654 4.429179955171728e-20 3.633124638904377e-19 1.1718740706428754e-19 5982/7316/5981/6119/7311/5111/6118/5983/6117/5985/7314/6233/5984 13 Tomato_spotted_wilt_virus R-HSA-69239 Synthesis of DNA 25/197 119/10654 7.45508728403392e-20 6.033650641878119e-19 1.9461701541478023e-19 5982/7316/5981/9978/54107/10714/6119/7311/5111/6118/56655/5426/3978/5983/6117/5985/5701/7314/6233/5424/57804/2237/5427/5984/5425 25 Tomato_spotted_wilt_virus R-HSA-1839126 FGFR2 mutant receptor activation 16/197 33/10654 8.957006266796437e-20 7.153819478875576e-19 2.307483608897697e-19 2962/5436/5433/5438/5439/5431/2963/5430/5437/5432/5441/5434/5440/22916/5435/4686 16 Tomato_spotted_wilt_virus R-HSA-110320 Translesion Synthesis by POLH 13/197 19/10654 4.888417340434975e-19 3.853596526810429e-18 1.2429878678344573e-18 5982/7316/5981/6119/7311/5111/6118/5983/6117/5985/7314/6233/5984 13 Tomato_spotted_wilt_virus R-HSA-5654738 Signaling by FGFR2 20/197 73/10654 1.5079135587242345e-18 1.173466064289244e-17 3.7850461797936255e-18 7316/2962/5436/5433/7311/5438/5439/5431/7314/2963/5430/6233/5437/5432/5441/5434/5440/22916/5435/4686 20 Tomato_spotted_wilt_virus R-HSA-69190 DNA strand elongation 15/197 32/10654 2.537612249665319e-18 1.949785614616264e-17 6.289085655399724e-18 5982/5981/10714/6119/5111/6118/3978/5983/6117/5985/5424/57804/2237/5984/5425 15 Tomato_spotted_wilt_virus R-HSA-5693607 Processing of DNA double-strand break ends 22/197 98/10654 2.997543811266437e-18 2.2743863667984093e-17 7.336094064415228e-18 5982/7316/672/7329/9656/7336/7158/6119/7311/6118/1111/5983/6117/7341/5985/7314/545/6233/472/6613/7334/5984 22 Tomato_spotted_wilt_virus R-HSA-5655253 Signaling by FGFR2 in disease 16/197 43/10654 1.7320211718916788e-17 1.2979467300472211e-16 4.18656189697014e-17 2962/5436/5433/5438/5439/5431/2963/5430/5437/5432/5441/5434/5440/22916/5435/4686 16 Tomato_spotted_wilt_virus R-HSA-174414 Processive synthesis on the C-strand of the telomere 10/197 11/10654 4.02654137549005e-17 2.9806227011249516e-16 9.614078252132856e-17 10714/6119/5111/6118/3978/6117/5424/57804/2237/5425 10 Tomato_spotted_wilt_virus R-HSA-190236 Signaling by FGFR 20/197 87/10654 6.658840118461923e-17 4.869778255308901e-16 1.570760002579477e-16 7316/2962/5436/5433/7311/5438/5439/5431/7314/2963/5430/6233/5437/5432/5441/5434/5440/22916/5435/4686 20 Tomato_spotted_wilt_virus R-HSA-157579 Telomere Maintenance 19/197 82/10654 3.5093917571090793e-16 2.535953329244299e-15 8.179785298524923e-16 5982/5981/54107/10714/6119/5111/6118/56655/5426/3978/5983/6117/5985/5424/57804/2237/5427/5984/5425 19 Tomato_spotted_wilt_virus R-HSA-72165 mRNA Splicing - Minor Pathway 16/197 52/10654 5.852535037835867e-16 4.179398550548672e-15 1.3480761820897477e-15 2962/5436/5433/5438/5439/5431/2963/5430/5437/5432/5441/5434/5440/22916/5435/4686 16 Tomato_spotted_wilt_virus R-HSA-174437 Removal of the Flap Intermediate from the C-strand 9/197 10/10654 2.072817785851149e-15 1.4630237162926133e-14 4.719022131803105e-15 10714/6119/5111/6118/6117/5424/57804/2237/5425 9 Tomato_spotted_wilt_virus R-HSA-203927 MicroRNA (miRNA) biogenesis 12/197 24/10654 2.5435943573161678e-15 1.7746687067711652e-14 5.724241384885749e-15 5436/5433/5438/5439/5431/5430/5437/5432/5441/5434/5440/5435 12 Tomato_spotted_wilt_virus R-HSA-5250924 B-WICH complex positively regulates rRNA expression 19/197 91/10654 2.796256886277071e-15 1.9287817386024797e-14 6.221337091477694e-15 25885/9013/6908/79101/9014/84172/9015/9533/10849/2033/5437/64425/30834/5441/221830/5434/5440/5435/51082 19 Tomato_spotted_wilt_virus R-HSA-174411 Polymerase switching on the C-strand of the telomere 10/197 14/10654 3.4913932113621e-15 2.3288743728536207e-14 7.51184658546386e-15 5982/5981/10714/5111/5983/5985/5424/57804/5984/5425 10 Tomato_spotted_wilt_virus R-HSA-69091 Polymerase switching 10/197 14/10654 3.4913932113621e-15 2.3288743728536207e-14 7.51184658546386e-15 5982/5981/10714/5111/5983/5985/5424/57804/5984/5425 10 Tomato_spotted_wilt_virus R-HSA-69109 Leading Strand Synthesis 10/197 14/10654 3.4913932113621e-15 2.3288743728536207e-14 7.51184658546386e-15 5982/5981/10714/5111/5983/5985/5424/57804/5984/5425 10 Tomato_spotted_wilt_virus R-HSA-5250913 Positive epigenetic regulation of rRNA expression 20/197 106/10654 4.0192792902920705e-15 2.6518505752253116e-14 8.553614965610128e-15 25885/9013/6908/79101/9014/84172/9015/9533/10849/7270/2033/5437/64425/30834/5441/221830/5434/5440/5435/51082 20 Tomato_spotted_wilt_virus R-HSA-69183 Processive synthesis on the lagging strand 10/197 15/10654 1.0306925232379088e-14 6.727208189305491e-14 2.169878996290334e-14 10714/6119/5111/6118/3978/6117/5424/57804/2237/5425 10 Tomato_spotted_wilt_virus R-HSA-168325 Viral Messenger RNA Synthesis 14/197 43/10654 1.682849343517908e-14 1.0866910122503938e-13 3.5051509282679835e-14 2962/5436/5433/5438/5439/5431/2963/5430/5437/5432/5441/5434/5440/5435 14 Tomato_spotted_wilt_virus R-HSA-1226099 Signaling by FGFR in disease 16/197 63/10654 1.7321455329848886e-14 1.1067498300229762e-13 3.569851181553344e-14 2962/5436/5433/5438/5439/5431/2963/5430/5437/5432/5441/5434/5440/22916/5435/4686 16 Tomato_spotted_wilt_virus R-HSA-9018519 Estrogen-dependent gene expression 22/197 150/10654 3.873084971483329e-14 2.4489193517608134e-13 7.899054876051527e-14 2962/6908/5436/5433/1025/5438/5439/2099/5431/2957/2958/4609/2963/5430/2033/5437/5432/5441/5434/5440/5435/904 22 Tomato_spotted_wilt_virus R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 12/197 29/10654 4.5022281685023264e-14 2.8173737095679505e-13 9.087514263064924e-14 5436/5433/5438/5439/5431/5430/5437/5432/5441/5434/5440/5435 12 Tomato_spotted_wilt_virus R-HSA-5685938 HDR through Single Strand Annealing (SSA) 13/197 37/10654 4.796182489311575e-14 2.9706967051144146e-13 9.582061686487143e-14 5982/672/6119/5888/6118/5983/6117/5985/545/2072/472/2067/5984 13 Tomato_spotted_wilt_virus R-HSA-73886 Chromosome Maintenance 19/197 110/10654 1.0959189329982202e-13 6.719422144746663e-13 2.1673675867907384e-13 5982/5981/54107/10714/6119/5111/6118/56655/5426/3978/5983/6117/5985/5424/57804/2237/5427/5984/5425 19 Tomato_spotted_wilt_virus R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 9/197 14/10654 3.8922150333700683e-13 2.3162495345643446e-12 7.471124831855859e-13 10714/6119/5111/6118/3978/6117/5424/57804/5425 9 Tomato_spotted_wilt_virus R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 9/197 14/10654 3.8922150333700683e-13 2.3162495345643446e-12 7.471124831855859e-13 10714/6119/5111/6118/3978/6117/5424/57804/5425 9 Tomato_spotted_wilt_virus R-HSA-69166 Removal of the Flap Intermediate 9/197 14/10654 3.8922150333700683e-13 2.3162495345643446e-12 7.471124831855859e-13 10714/6119/5111/6118/6117/5424/57804/2237/5425 9 Tomato_spotted_wilt_virus R-HSA-69481 G2/M Checkpoints 22/197 168/10654 4.214106015048071e-13 2.483458593334154e-12 8.010462123647841e-13 5982/7316/672/9656/7336/7158/6119/7311/6118/1111/5983/6117/7341/5985/5701/7314/545/6233/7157/472/7334/5984 22 Tomato_spotted_wilt_virus R-HSA-5358508 Mismatch Repair 9/197 15/10654 9.57593370493945e-13 5.58903053740216e-12 1.8027567501201801e-12 10714/6119/5111/6118/3978/6117/5424/57804/5425 9 Tomato_spotted_wilt_virus R-HSA-69473 G2/M DNA damage checkpoint 17/197 95/10654 1.2522424470645522e-12 7.239153955887459e-12 2.3350084727218716e-12 5982/672/9656/7336/7158/6119/6118/1111/5983/6117/7341/5985/545/7157/472/7334/5984 17 Tomato_spotted_wilt_virus R-HSA-69206 G1/S Transition 19/197 131/10654 2.8542081680347438e-12 1.63443807358216e-11 5.271923726459407e-12 7316/1869/54107/5925/6119/7311/902/5111/6118/56655/5426/6117/5701/4609/7314/6233/1022/4331/5427 19 Tomato_spotted_wilt_virus R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 12/197 39/10654 2.886177450999438e-12 1.63729879696884e-11 5.2811510662655735e-12 5982/672/6119/5888/6118/1111/5983/6117/5985/545/472/5984 12 Tomato_spotted_wilt_virus R-HSA-6783310 Fanconi Anemia Pathway 12/197 40/10654 4.056971344278919e-12 2.2801681536826888e-11 7.354743372669386e-12 7316/6119/7311/6118/2177/6117/7314/545/6233/2072/55215/2067 12 Tomato_spotted_wilt_virus R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 12/197 42/10654 7.774457321398622e-12 4.329445499164186e-11 1.3964742267311865e-11 5982/672/6119/5888/6118/1111/5983/6117/5985/545/472/5984 12 Tomato_spotted_wilt_virus R-HSA-8939211 ESR-mediated signaling 23/197 223/10654 1.891523715912896e-11 1.0437771777810254e-10 3.3667312072708004e-11 2962/6908/5436/5433/1025/5438/5439/2099/5431/2957/2958/4609/2963/5430/2033/5437/5432/2100/5441/5434/5440/5435/904 23 Tomato_spotted_wilt_virus R-HSA-72163 mRNA Splicing - Major Pathway 21/197 183/10654 1.969321529802863e-11 1.0769172690003044e-10 3.4736254579737556e-11 10450/2962/5436/84844/5433/27339/5438/5439/9716/5431/2963/5430/56949/5437/5432/5441/5434/5440/22916/5435/4686 21 Tomato_spotted_wilt_virus R-HSA-453279 Mitotic G1-G1/S phases 19/197 149/10654 2.9316297020024075e-11 1.588838597424519e-10 5.124841396357593e-11 7316/1869/54107/5925/6119/7311/902/5111/6118/56655/5426/6117/5701/4609/7314/6233/1022/4331/5427 19 Tomato_spotted_wilt_virus R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 13/197 59/10654 3.81644165346744e-11 2.0500708704909167e-10 6.612558430786621e-11 7316/9646/7336/79577/23168/7311/5111/54623/80349/7314/6233/123169/7334 13 Tomato_spotted_wilt_virus R-HSA-72172 mRNA Splicing 21/197 191/10654 4.479869528604689e-11 2.3853340384763563e-10 7.693958747188109e-11 10450/2962/5436/84844/5433/27339/5438/5439/9716/5431/2963/5430/56949/5437/5432/5441/5434/5440/22916/5435/4686 21 Tomato_spotted_wilt_virus R-HSA-8852135 Protein ubiquitination 14/197 79/10654 1.491409391141304e-10 7.87204782976323e-10 2.5391500846890853e-10 7316/9646/7336/79577/23168/7311/7874/5111/54623/80349/7314/6233/123169/7334 14 Tomato_spotted_wilt_virus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 10/197 32/10654 1.684331216429874e-10 8.813698692870116e-10 2.8428820894369925e-10 7316/1025/905/7311/4609/7314/6233/8812/904/54778 10 Tomato_spotted_wilt_virus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 11/197 44/10654 2.942302846278574e-10 1.5264767758043542e-9 4.923691672584928e-10 7316/142/1025/905/7311/4609/7314/6233/8812/904/54778 11 Tomato_spotted_wilt_virus R-HSA-168273 Influenza Viral RNA Transcription and Replication 17/197 134/10654 3.668774389417816e-10 1.8872424189632323e-9 6.087350904832416e-10 2962/5436/5433/7311/5438/5439/5431/11224/2963/5430/6233/5437/5432/5441/5434/5440/5435 17 Tomato_spotted_wilt_virus R-HSA-168254 Influenza Infection 18/197 155/10654 4.770241109322017e-10 2.4332238263516507e-9 7.848428538999516e-10 2962/3839/5436/5433/7311/5438/5439/5431/11224/2963/5430/6233/5437/5432/5441/5434/5440/5435 18 Tomato_spotted_wilt_virus R-HSA-5693565 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 13/197 76/10654 1.0936894561555462e-9 5.5322458323868045e-9 1.7844406916222073e-9 7316/672/7329/9656/7336/7158/7311/7341/7314/6233/7157/472/7334 13 Tomato_spotted_wilt_virus R-HSA-168255 Influenza Life Cycle 17/197 144/10654 1.145314563619006e-9 5.745503637328402e-9 1.8532275670564171e-9 2962/5436/5433/7311/5438/5439/5431/11224/2963/5430/6233/5437/5432/5441/5434/5440/5435 17 Tomato_spotted_wilt_virus R-HSA-3232118 SUMOylation of transcription factors 8/197 20/10654 1.2350052597002765e-9 6.144657316705475e-9 1.9819756540487613e-9 7329/7158/7341/7157/6612/8554/6613/10401 8 Tomato_spotted_wilt_virus R-HSA-9006931 Signaling by Nuclear Receptors 24/197 299/10654 1.25519737390533e-9 6.194348015939311e-9 1.998003522005917e-9 2962/6908/5436/5433/1025/5438/5439/2099/6257/5431/2957/2958/4609/2963/5430/2033/5437/5432/2100/5441/5434/5440/5435/904 24 Tomato_spotted_wilt_virus R-HSA-5693606 DNA Double Strand Break Response 13/197 77/10654 1.2947200979402513e-9 6.337863705239779e-9 2.0442948914846075e-9 7316/672/7329/9656/7336/7158/7311/7341/7314/6233/7157/472/7334 13 Tomato_spotted_wilt_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 12/197 63/10654 1.3359641817631109e-9 6.487442066641666e-9 2.0925417920668516e-9 7316/7311/7314/9533/6233/2033/5437/5441/5434/5440/5435/51082 12 Tomato_spotted_wilt_virus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 21/197 244/10654 4.2198003270942215e-9 2.032872062338248e-8 6.557083215033628e-9 10450/2962/5436/84844/5433/27339/5438/5439/9716/5431/2963/5430/56949/5437/5432/5441/5434/5440/22916/5435/4686 21 Tomato_spotted_wilt_virus R-HSA-69620 Cell Cycle Checkpoints 23/197 293/10654 4.3826739123158844e-009 2.0947110746265687e-8 6.756546603321629e-9 5982/7316/672/9656/7336/7158/6119/7311/6118/1111/5983/6117/10726/7341/5985/5701/7314/545/6233/7157/472/7334/5984 23 Tomato_spotted_wilt_virus R-HSA-69002 DNA Replication Pre-Initiation 13/197 85/10654 4.57356691108595e-9 2.1688711836165402e-8 6.995752018601864e-9 7316/1869/54107/6119/7311/6118/56655/5426/6117/5701/7314/6233/5427 13 Tomato_spotted_wilt_virus R-HSA-5663202 Diseases of signal transduction 26/197 377/10654 6.2010289708574656e-9 2.9178485157445595e-8 9.411598438021123e-9 7316/2962/5436/9978/5433/7311/5438/5439/2099/5431/5701/4609/7314/2963/5430/6233/2033/5437/5432/2100/5441/5434/5440/22916/5435/4686 26 Tomato_spotted_wilt_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 18/197 182/10654 6.497069161478473e-9 3.033631523859564e-8 9.785059627813732e-9 672/7329/142/9656/7158/5111/2099/367/6117/7341/7508/7157/2033/6612/8554/6613/10401/1069 18 Tomato_spotted_wilt_virus R-HSA-2990846 SUMOylation 18/197 188/10654 1.0878645967345349e-8 5.040716108533303e-8 1.6258964643842788e-8 672/7329/142/9656/7158/5111/2099/367/6117/7341/7508/7157/2033/6612/8554/6613/10401/1069 18 Tomato_spotted_wilt_virus R-HSA-8951664 Neddylation 20/197 234/10654 1.1372979456232892e-8 5.2298473711616405e-8 1.686901259058467e-8 7316/9318/9978/8533/50813/7311/1642/10987/1643/5701/10920/7314/6233/51138/8451/8450/10980/2873/64708/1161 20 Tomato_spotted_wilt_virus R-HSA-176187 Activation of ATR in response to replication stress 9/197 37/10654 1.6739121301532348e-8 7.639583932353485e-8 2.4641682327542675e-8 5982/6119/6118/1111/5983/6117/5985/545/5984 9 Tomato_spotted_wilt_virus R-HSA-73780 RNA Polymerase III Chain Elongation 7/197 18/10654 1.7797278063386695e-8 8.0619013316983e-8 2.600387839583602e-8 9533/5437/5441/5434/5440/5435/51082 7 Tomato_spotted_wilt_virus R-HSA-76066 RNA Polymerase III Transcription Initiation From Type 2 Promoter 8/197 27/10654 1.9476046832558315e-8 8.757007723972516e-8 2.8245962657745397e-8 6908/9533/5437/5441/5434/5440/5435/51082 8 Tomato_spotted_wilt_virus R-HSA-76061 RNA Polymerase III Transcription Initiation From Type 1 Promoter 8/197 28/10654 2.6837177894025817e-8 1.1890632833338444e-7 3.835355427037113e-8 6908/9533/5437/5441/5434/5440/5435/51082 8 Tomato_spotted_wilt_virus R-HSA-76071 RNA Polymerase III Transcription Initiation From Type 3 Promoter 8/197 28/10654 2.6837177894025817e-8 1.1890632833338444e-7 3.835355427037113e-8 6908/9533/5437/5441/5434/5440/5435/51082 8 Tomato_spotted_wilt_virus R-HSA-6804760 Regulation of TP53 Activity through Methylation 7/197 19/10654 2.7739850427473826e-8 1.220151391991059e-7 3.935630953096973e-8 7316/7311/7314/6233/7157/2033/472 7 Tomato_spotted_wilt_virus R-HSA-5689877 Josephin domain DUBs 6/197 12/10654 3.1208599620866534e-8 1.3628503575443157e-7 4.39591028359044e-8 7316/5886/7311/5887/7314/6233 6 Tomato_spotted_wilt_virus R-HSA-4090294 SUMOylation of intracellular receptors 8/197 30/10654 4.8959028262169897e-8 2.1227235825097947e-7 6.846901696814739e-8 7329/2099/367/7341/6612/8554/6613/10401 8 Tomato_spotted_wilt_virus R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 13/197 106/10654 7.013188639283431e-8 3.0191528397482574e-7 9.738358244917644e-8 7316/9318/8533/50813/7311/10987/10920/7314/6233/51138/10980/2873/64708 13 Tomato_spotted_wilt_virus R-HSA-69231 Cyclin D associated events in G1 9/197 44/10654 8.529494552172207e-8 3.605414813800582e-7 1.1629361924337262e-7 7316/1869/5925/7311/902/7314/6233/1022/4331 9 Tomato_spotted_wilt_virus R-HSA-69236 G1 Phase 9/197 44/10654 8.529494552172207e-8 3.605414813800582e-7 1.1629361924337262e-7 7316/1869/5925/7311/902/7314/6233/1022/4331 9 Tomato_spotted_wilt_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 11/197 73/10654 8.553208124996438e-8 3.605414813800582e-7 1.1629361924337262e-7 7316/142/1025/905/7311/4609/7314/6233/8812/904/54778 11 Tomato_spotted_wilt_virus R-HSA-73980 RNA Polymerase III Transcription Termination 7/197 23/10654 1.2674950003553058e-7 5.30599631183221e-7 1.711463303565059e-7 9533/5437/5441/5434/5440/5435/51082 7 Tomato_spotted_wilt_virus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 11/197 77/10654 1.5057729199498875e-7 6.260302482257409e-7 2.0192773115405847e-7 672/7329/142/9656/6117/7341/7508/6612/8554/6613/1069 11 Tomato_spotted_wilt_virus R-HSA-76046 RNA Polymerase III Transcription Initiation 8/197 36/10654 2.3015017220246927e-7 9.503479899789037e-7 3.0653728628470667e-7 6908/9533/5437/5441/5434/5440/5435/51082 8 Tomato_spotted_wilt_virus R-HSA-69202 Cyclin E associated events during G1/S transition 11/197 83/10654 3.302577196971248e-7 1.3545029449740189e-6 4.36898548105727e-7 7316/1869/5925/7311/902/5701/4609/7314/6233/1022/4331 11 Tomato_spotted_wilt_virus R-HSA-5689896 Ovarian tumor domain proteases 8/197 38/10654 3.6033844761665257e-7 1.467955957740323e-6 4.734931208526837e-7 7316/10318/7706/7311/2099/7314/6233/7157 8 Tomato_spotted_wilt_virus R-HSA-5617472 Activation of anterior HOX genes in hindbrain development during early embryogenesis 13/197 122/10654 3.736627488725446e-7 1.502074758712812e-6 4.844982313718599e-7 5436/5433/5438/5439/5431/5430/2033/5437/5432/5441/5434/5440/5435 13 Tomato_spotted_wilt_virus R-HSA-5619507 Activation of HOX genes during differentiation 13/197 122/10654 3.736627488725446e-7 1.502074758712812e-6 4.844982313718599e-7 5436/5433/5438/5439/5431/5430/2033/5437/5432/5441/5434/5440/5435 13 Tomato_spotted_wilt_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 11/197 85/10654 4.226766241613871e-7 1.6879257293813287e-6 5.444449590998478e-7 7316/1869/5925/7311/902/5701/4609/7314/6233/1022/4331 11 Tomato_spotted_wilt_virus R-HSA-5685939 HDR through MMEJ (alt-NHEJ) 5/197 10/10654 4.802978760068873e-7 1.9054954950077165e-6 6.146226689871418e-7 10038/142/2237/7515/3980 5 Tomato_spotted_wilt_virus R-HSA-5578749 Transcriptional regulation by small RNAs 12/197 106/10654 5.50089874472229e-7 2.1682113883418376e-6 6.993623831294231e-7 5436/5433/5438/5439/5431/5430/5437/5432/5441/5434/5440/5435 12 Tomato_spotted_wilt_virus R-HSA-74158 RNA Polymerase III Transcription 8/197 41/10654 6.71352016400734e-7 2.6122479099695226e-6 8.425875509482896e-7 6908/9533/5437/5441/5434/5440/5435/51082 8 Tomato_spotted_wilt_virus R-HSA-749476 RNA Polymerase III Abortive And Retractive Initiation 8/197 41/10654 6.71352016400734e-7 2.6122479099695226e-6 8.425875509482896e-7 6908/9533/5437/5441/5434/5440/5435/51082 8 Tomato_spotted_wilt_virus R-HSA-2559585 Oncogene Induced Senescence 7/197 33/10654 1.8881579590794454e-6 7.2538726655773635e-6 2.33975603190391e-6 7316/1869/5925/7311/7314/6233/7157 7 Tomato_spotted_wilt_virus R-HSA-68962 Activation of the pre-replicative complex 7/197 33/10654 1.8881579590794454e-6 7.2538726655773635e-6 2.33975603190391e-6 54107/6119/6118/56655/5426/6117/5427 7 Tomato_spotted_wilt_virus R-HSA-5688426 Deubiquitination 19/197 297/10654 2.427079602535166e-6 9.26564351408079e-6 2.988658100440522e-6 7316/672/10318/7706/5886/7311/7874/2099/367/5887/1643/5701/6881/4609/7314/6233/7157/51616/2033 19 Tomato_spotted_wilt_virus R-HSA-9006936 Signaling by TGF-beta family members 11/197 102/10654 2.6844907778482868e-6 1.0184286888461939e-5 3.2849689781564565e-6 7316/142/1025/905/7311/4609/7314/6233/8812/904/54778 11 Tomato_spotted_wilt_virus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 6/197 23/10654 2.8765974998785405e-6 1.0845308586498597e-5 3.4981832950468035e-6 7316/142/7311/7314/6233/54778 6 Tomato_spotted_wilt_virus R-HSA-8856828 Clathrin-mediated endocytosis 13/197 146/10654 2.9279969511261666e-6 1.0970951539096193e-5 3.5387097654936125e-6 7316/9318/8533/50813/7311/10987/10920/7314/6233/51138/10980/2873/64708 13 Tomato_spotted_wilt_virus R-HSA-6804757 Regulation of TP53 Degradation 7/197 36/10654 3.5201661990135856e-6 1.3108839771786788e-5 4.2282913336553244e-6 7316/7311/7874/7314/6233/7157/472 7 Tomato_spotted_wilt_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 7/197 37/10654 4.274099801993137e-6 1.5819381584206306e-5 5.102583845768443e-6 7316/7311/7874/7314/6233/7157/472 7 Tomato_spotted_wilt_virus R-HSA-937039 IRAK1 recruits IKK complex 5/197 15/10654 5.307320210228135e-6 1.9290678847954957e-5 6.222260063677486e-6 7316/7311/7314/6233/7334 5 Tomato_spotted_wilt_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 5/197 15/10654 5.307320210228135e-6 1.9290678847954957e-5 6.222260063677486e-6 7316/7311/7314/6233/7334 5 Tomato_spotted_wilt_virus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 5/197 15/10654 5.307320210228135e-6 1.9290678847954957e-5 6.222260063677486e-6 7316/7311/7314/6233/7334 5 Tomato_spotted_wilt_virus R-HSA-211000 Gene Silencing by RNA 12/197 136/10654 7.812646463616793e-6 2.822783573461544e-5 9.104963923763931e-6 5436/5433/5438/5439/5431/5430/5437/5432/5441/5434/5440/5435 12 Tomato_spotted_wilt_virus R-HSA-3899300 SUMOylation of transcription cofactors 7/197 45/10654 1.6623236982900432e-5 5.9705945849825815e-5 1.9258312543254316e-5 7329/7341/2033/6612/8554/6613/10401 7 Tomato_spotted_wilt_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 23/197 473/10654 2.0620415444150512e-5 7.362701279176096e-5 2.3748589923294086e-5 7316/2962/5436/5433/7311/5438/5439/1111/2099/5431/7314/2963/5430/6233/5437/5432/25920/5441/5434/5440/22916/5435/4686 23 Tomato_spotted_wilt_virus R-HSA-3215018 Processing and activation of SUMO 4/197 10/10654 2.182575597046988e-5 7.702461554694894e-5 2.484449578033903e-5 7329/7341/6612/6613 4 Tomato_spotted_wilt_virus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 4/197 10/10654 2.182575597046988e-5 7.702461554694894e-5 2.484449578033903e-5 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 7/197 47/10654 2.2329262303962726e-5 7.834602438442414e-5 2.5270719735546502e-005 7316/9978/7311/4609/7314/6233/2033 7 Tomato_spotted_wilt_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 5/197 20/10654 2.541175724179047e-5 8.86490611825679e-5 2.859399181471886e-5 7316/7311/7314/6233/7334 5 Tomato_spotted_wilt_virus R-HSA-4755510 SUMOylation of immune response proteins 4/197 11/10654 3.3801993826551596e-5 1.1557626090655056e-4 3.7279432114139264e-5 7329/7341/6612/10401 4 Tomato_spotted_wilt_virus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 4/197 11/10654 3.3801993826551596e-5 1.1557626090655056e-4 3.7279432114139264e-5 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 4/197 11/10654 3.3801993826551596e-5 1.1557626090655056e-4 3.7279432114139264e-5 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-69615 G1/S DNA Damage Checkpoints 8/197 68/10654 3.389221489516639e-5 1.1557626090655056e-4 3.7279432114139264e-5 7316/7311/1111/5701/7314/6233/7157/472 8 Tomato_spotted_wilt_virus R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 7/197 52/10654 4.393210143944988e-5 1.4897645571925182e-4 4.8052754294252737e-5 7316/7311/5701/7314/6233/7157/472 7 Tomato_spotted_wilt_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 4/197 12/10654 4.997070262055445e-5 1.6851231383709195e-4 5.4354097587269755e-5 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 5/197 23/10654 5.271759249703294e-5 1.767932521861823e-4 5.702513640272246e-5 7316/7311/7314/6233/7334 5 Tomato_spotted_wilt_virus R-HSA-5689901 Metalloprotease DUBs 6/197 37/10654 5.3398712214745194e-5 1.7809350722170514e-4 5.7444537142525196e-5 7316/672/7311/7314/6233/2033 6 Tomato_spotted_wilt_virus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 5/197 24/10654 6.559676281757765e-5 2.1758051929109088e-4 7.01811785106094e-5 7316/7311/7314/6233/7334 5 Tomato_spotted_wilt_virus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 4/197 13/10654 7.113800678500177e-5 2.3215467805643052e-4 7.488211240526503e-5 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-209543 p75NTR recruits signalling complexes 4/197 13/10654 7.113800678500177e-5 2.3215467805643052e-4 7.488211240526503e-5 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-209560 NF-kB is activated and signals survival 4/197 13/10654 7.113800678500177e-5 2.3215467805643052e-4 7.488211240526503e-5 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-453274 Mitotic G2-G2/M phases 13/197 198/10654 7.69112438203003e-5 2.49653074860547e-4 8.052626710146838e-5 7316/9978/1869/7311/902/5701/7314/6233/7157/2033/1022/4331/1069 13 Tomato_spotted_wilt_virus R-HSA-69541 Stabilization of p53 7/197 57/10654 8.030509511454242e-5 2.592829400772726e-4 8.363240588636556e-5 7316/7311/5701/7314/6233/7157/472 7 Tomato_spotted_wilt_virus R-HSA-937041 IKK complex recruitment mediated by RIP1 5/197 25/10654 8.077261754636554e-5 2.5941258651134333e-4 8.367422369047056e-5 7316/7311/7314/6233/7334 5 Tomato_spotted_wilt_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 7/197 58/10654 8.991476609044873e-5 2.8133125266444525e-4 9.074414808911267e-5 7316/9978/7311/4609/7314/6233/2033 7 Tomato_spotted_wilt_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 7/197 58/10654 8.991476609044873e-5 2.8133125266444525e-4 9.074414808911267e-5 7316/9978/7311/4609/7314/6233/2033 7 Tomato_spotted_wilt_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 7/197 58/10654 8.991476609044873e-5 2.8133125266444525e-4 9.074414808911267e-5 7316/9978/7311/4609/7314/6233/2033 7 Tomato_spotted_wilt_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 7/197 58/10654 8.991476609044873e-5 2.8133125266444525e-4 9.074414808911267e-5 7316/9978/7311/4609/7314/6233/2033 7 Tomato_spotted_wilt_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 7/197 58/10654 8.991476609044873e-5 2.8133125266444525e-4 9.074414808911267e-5 7316/9978/7311/4609/7314/6233/2033 7 Tomato_spotted_wilt_virus R-HSA-174490 Membrane binding and targetting of GAG proteins 4/197 14/10654 9.815640656727696e-5 3.0398438156294447e-4 9.805097541092114e-5 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-174495 Synthesis And Processing Of GAG, GAGPOL Polyproteins 4/197 14/10654 9.815640656727696e-5 3.0398438156294447e-4 9.805097541092114e-5 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-2691230 Signaling by NOTCH1 HD Domain Mutants in Cancer 4/197 15/10654 1.319197106971128e-4 4.0037632196573736e-4 1.2914245362980516e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-2691232 Constitutive Signaling by NOTCH1 HD Domain Mutants 4/197 15/10654 1.319197106971128e-4 4.0037632196573736e-4 1.2914245362980516e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 4/197 15/10654 1.319197106971128e-4 4.0037632196573736e-4 1.2914245362980516e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 4/197 15/10654 1.319197106971128e-4 4.0037632196573736e-4 1.2914245362980516e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-4615885 SUMOylation of DNA replication proteins 6/197 45/10654 1.6546234209150105e-4 4.996798092016972e-4 1.6117305906791933e-4 7329/5111/7341/6612/6613/10401 6 Tomato_spotted_wilt_virus R-HSA-1295596 Spry regulation of FGF signaling 4/197 16/10654 1.7335822406071218e-4 5.010878190707252e-4 1.6162721641750608e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-175474 Assembly Of The HIV Virion 4/197 16/10654 1.7335822406071218e-4 5.010878190707252e-4 1.6162721641750608e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-193639 p75NTR signals via NF-kB 4/197 16/10654 1.7335822406071218e-4 5.010878190707252e-4 1.6162721641750608e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-205043 NRIF signals cell death from the nucleus 4/197 16/10654 1.7335822406071218e-4 5.010878190707252e-4 1.6162721641750608e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 4/197 16/10654 1.7335822406071218e-4 5.010878190707252e-4 1.6162721641750608e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-3229121 Glycogen storage diseases 4/197 16/10654 1.7335822406071218e-4 5.010878190707252e-4 1.6162721641750608e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-3322077 Glycogen synthesis 4/197 16/10654 1.7335822406071218e-4 5.010878190707252e-4 1.6162721641750608e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 4/197 16/10654 1.7335822406071218e-4 5.010878190707252e-4 1.6162721641750608e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 4/197 16/10654 1.7335822406071218e-4 5.010878190707252e-4 1.6162721641750608e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 5/197 30/10654 2.009808198590601e-4 5.781770504950212e-4 1.864925542219266e-4 7316/7311/7874/7314/6233 5 Tomato_spotted_wilt_virus R-HSA-69563 p53-Dependent G1 DNA Damage Response 7/197 66/10654 2.0561211647165205e-4 5.859462661891681e-4 1.8899853552620355e-4 7316/7311/5701/7314/6233/7157/472 7 Tomato_spotted_wilt_virus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 7/197 66/10654 2.0561211647165205e-4 5.859462661891681e-4 1.8899853552620355e-4 7316/7311/5701/7314/6233/7157/472 7 Tomato_spotted_wilt_virus R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 4/197 17/10654 2.2343418074230865e-4 6.337595687410343e-4 2.0442084416167936e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-5693571 Nonhomologous End-Joining (NHEJ) 7/197 69/10654 2.7185885451031205e-4 7.67527091570974e-4 2.47567916469611e-4 672/9656/7336/7158/7341/472/7334 7 Tomato_spotted_wilt_virus R-HSA-69275 G2/M Transition 12/197 196/10654 2.7901953123711585e-4 7.84096553059858e-4 2.5291244059504655e-4 7316/9978/7311/902/5701/7314/6233/7157/2033/1022/4331/1069 12 Tomato_spotted_wilt_virus R-HSA-5675482 Regulation of necroptotic cell death 4/197 18/10654 2.8313741310444175e-4 7.883688520843859e-4 2.5429048207352087e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 4/197 18/10654 2.8313741310444175e-4 7.883688520843859e-4 2.5429048207352087e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-1980145 Signaling by NOTCH2 5/197 33/10654 3.2000332185938454e-4 8.829182562211202e-4 2.847876452911269e-4 7316/7311/7314/6233/2033 5 Tomato_spotted_wilt_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 5/197 33/10654 3.2000332185938454e-4 8.829182562211202e-4 2.847876452911269e-4 7316/7311/7314/6233/7334 5 Tomato_spotted_wilt_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 4/197 19/10654 3.5348124787966737e-4 9.643413139218056e-4 3.110508703536909e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 4/197 19/10654 3.5348124787966737e-4 9.643413139218056e-4 3.110508703536909e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-1169408 ISG15 antiviral mechanism 7/197 72/10654 3.5428025206682477e-4 9.643413139218056e-4 3.110508703536909e-4 7316/3839/7706/7311/7314/6233/7334 7 Tomato_spotted_wilt_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 5/197 34/10654 3.695987207644736e-4 9.93437010230864e-4 3.2043576502721003e-4 7316/7706/7311/7314/6233 5 Tomato_spotted_wilt_virus R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 6/197 52/10654 3.715159824092357e-4 9.93437010230864e-4 3.2043576502721003e-4 7316/7311/1111/5701/7314/6233 6 Tomato_spotted_wilt_virus R-HSA-69610 p53-Independent DNA Damage Response 6/197 52/10654 3.715159824092357e-4 9.93437010230864e-4 3.2043576502721003e-4 7316/7311/1111/5701/7314/6233 6 Tomato_spotted_wilt_virus R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 6/197 52/10654 3.715159824092357e-4 9.93437010230864e-4 3.2043576502721003e-4 7316/7311/1111/5701/7314/6233 6 Tomato_spotted_wilt_virus R-HSA-1980143 Signaling by NOTCH1 7/197 73/10654 3.8581439942798255e-4 0.0010226608753396743 3.298620008899323e-4 7316/9978/7311/4609/7314/6233/2033 7 Tomato_spotted_wilt_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 7/197 73/10654 3.8581439942798255e-4 0.0010226608753396743 3.298620008899323e-4 7316/9978/7311/2099/5701/7314/6233 7 Tomato_spotted_wilt_virus R-HSA-8878159 Transcriptional regulation by RUNX3 8/197 96/10654 3.9125218933040067e-4 0.0010325655605371879 3.330567835947576e-4 7316/7311/5701/4609/7314/6233/7157/2033 8 Tomato_spotted_wilt_virus R-HSA-8878166 Transcriptional regulation by RUNX2 9/197 121/10654 3.9931479283526386e-4 0.0010492817283593297 3.38448628240415e-4 7316/9978/5925/7311/2099/367/5701/7314/6233 9 Tomato_spotted_wilt_virus R-HSA-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle 5/197 35/10654 4.247906475460082e-4 0.0011114134614673577 3.584893849526204e-4 7316/7311/5887/7314/6233 5 Tomato_spotted_wilt_virus R-HSA-5213460 RIPK1-mediated regulated necrosis 4/197 20/10654 4.354986205391366e-4 0.0011248836709244934 3.6283423704492457e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-5218859 Regulated Necrosis 4/197 20/10654 4.354986205391366e-4 0.0011248836709244934 3.6283423704492457e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-8876384 Listeria monocytogenes entry into host cells 4/197 20/10654 4.354986205391366e-4 0.0011248836709244934 3.6283423704492457e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-1234174 Cellular response to hypoxia 7/197 75/10654 4.556144411124711e-4 0.0011609404865089666 3.7446445936125517e-4 7316/9978/7311/5701/7314/6233/2033 7 Tomato_spotted_wilt_virus R-HSA-180585 Vif-mediated degradation of APOBEC3G 6/197 54/10654 4.571083628923279e-4 0.0011609404865089666 3.7446445936125517e-4 7316/9978/7311/5701/7314/6233 6 Tomato_spotted_wilt_virus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 6/197 54/10654 4.571083628923279e-4 0.0011609404865089666 3.7446445936125517e-4 7316/9978/7311/5701/7314/6233 6 Tomato_spotted_wilt_virus R-HSA-9604323 Negative regulation of NOTCH4 signaling 6/197 54/10654 4.571083628923279e-4 0.0011609404865089666 3.7446445936125517e-4 7316/9978/7311/5701/7314/6233 6 Tomato_spotted_wilt_virus R-HSA-168638 NOD1/2 Signaling Pathway 5/197 36/10654 4.859774360452802e-4 0.0012291179319978546 3.964552767737813e-4 7316/7311/7314/6233/7334 5 Tomato_spotted_wilt_virus R-HSA-8941858 Regulation of RUNX3 expression and activity 6/197 55/10654 5.052942560274247e-4 0.0012726705950566258 4.105033047438349e-4 7316/7311/5701/7314/6233/2033 6 Tomato_spotted_wilt_virus R-HSA-4641263 Regulation of FZD by ubiquitination 4/197 21/10654 5.302383994876275e-4 0.0013190766741352044 4.254717096837736e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-6807004 Negative regulation of MET activity 4/197 21/10654 5.302383994876275e-4 0.0013190766741352044 4.254717096837736e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-901032 ER Quality Control Compartment (ERQC) 4/197 21/10654 5.302383994876275e-4 0.0013190766741352044 4.254717096837736e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-4641258 Degradation of DVL 6/197 57/10654 6.134657408301399e-4 0.0015198926721791627 4.902454470221526e-4 7316/9978/7311/5701/7314/6233 6 Tomato_spotted_wilt_virus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 5/197 38/10654 6.279805871297702e-4 0.0015495293349096363 4.998048318619481e-4 7329/2099/7341/4609/2033 5 Tomato_spotted_wilt_virus R-HSA-2979096 NOTCH2 Activation and Transmission of Signal to the Nucleus 4/197 22/10654 6.387619119105215e-4 0.0015509139221187463 5.002514341699242e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-5205685 Pink/Parkin Mediated Mitophagy 4/197 22/10654 6.387619119105215e-4 0.0015509139221187463 5.002514341699242e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-912631 Regulation of signaling by CBL 4/197 22/10654 6.387619119105215e-4 0.0015509139221187463 5.002514341699242e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-9613829 Chaperone Mediated Autophagy 4/197 22/10654 6.387619119105215e-4 0.0015509139221187463 5.002514341699242e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 7/197 80/10654 6.747681277332298e-4 0.0016318097750361374 5.263446079193993e-4 7316/3839/7706/7311/7314/6233/7334 7 Tomato_spotted_wilt_virus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 4/197 23/10654 7.62139663365993e-4 0.001835788792314118 5.921385855725761e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-9013694 Signaling by NOTCH4 7/197 82/10654 7.828748518976917e-4 0.0018782807711537504 6.058444870104874e-4 7316/9978/7311/5701/7314/6233/2033 7 Tomato_spotted_wilt_virus R-HSA-5689880 Ub-specific processing proteases 12/197 220/10654 7.885273813222167e-4 0.0018843941750495495 6.07816381790022e-4 7316/7311/7874/367/1643/5701/6881/4609/7314/6233/7157/51616 12 Tomato_spotted_wilt_virus R-HSA-5610780 Degradation of GLI1 by the proteasome 6/197 60/10654 8.084418754331711e-4 0.0019094327563732873 6.158926431725162e-4 7316/9978/7311/5701/7314/6233 6 Tomato_spotted_wilt_virus R-HSA-5610783 Degradation of GLI2 by the proteasome 6/197 60/10654 8.084418754331711e-4 0.0019094327563732873 6.158926431725162e-4 7316/9978/7311/5701/7314/6233 6 Tomato_spotted_wilt_virus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 6/197 60/10654 8.084418754331711e-4 0.0019094327563732873 6.158926431725162e-4 7316/9978/7311/5701/7314/6233 6 Tomato_spotted_wilt_virus R-HSA-5632684 Hedgehog 'on' state 7/197 85/10654 9.702410769970884e-4 0.0022826989679737703 7.362906581862849e-4 7316/9978/79577/7311/5701/7314/6233 7 Tomato_spotted_wilt_virus R-HSA-1643713 Signaling by EGFR in Cancer 4/197 25/10654 0.0010577674103193538 0.0024600184600147425 7.934855346618262e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 4/197 25/10654 0.0010577674103193538 0.0024600184600147425 7.934855346618262e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus 4/197 25/10654 0.0010577674103193538 0.0024600184600147425 7.934855346618262e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-3371511 HSF1 activation 3/197 12/10654 0.0012111173568372993 0.002805909296184125 9.050535491030039e-4 6119/6118/6117 3 Tomato_spotted_wilt_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 4/197 26/10654 0.0012321773463841333 0.002833074428996852 9.138157353566538e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-901042 Calnexin/calreticulin cycle 4/197 26/10654 0.0012321773463841333 0.002833074428996852 9.138157353566538e-4 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 6/197 66/10654 0.0013388987597243195 0.0030668360269911774 9.892161640862897e-4 7316/9978/7311/5701/7314/6233 6 Tomato_spotted_wilt_virus R-HSA-1500620 Meiosis 8/197 118/10654 0.001528955455828425 0.0034890073747663682 0.0011253886615911635 672/7329/6119/5888/6118/6117/545/472 8 Tomato_spotted_wilt_virus R-HSA-2564830 Cytosolic iron-sulfur cluster assembly 3/197 13/10654 0.0015531111618529915 0.00353033023306483 0.0011387174600712016 2068/5424/64210 3 Tomato_spotted_wilt_virus R-HSA-5658442 Regulation of RAS by GAPs 6/197 68/10654 0.0015645120802214817 0.00353033023306483 0.0011387174600712016 7316/9978/7311/5701/7314/6233 6 Tomato_spotted_wilt_virus R-HSA-68867 Assembly of the pre-replicative complex 6/197 68/10654 0.0015645120802214817 0.00353033023306483 0.0011387174600712016 7316/1869/7311/5701/7314/6233 6 Tomato_spotted_wilt_virus R-HSA-162588 Budding and maturation of HIV virion 4/197 29/10654 0.001874706892584716 0.004153091546711396 0.0013395907876325671 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-5205647 Mitophagy 4/197 29/10654 0.001874706892584716 0.004153091546711396 0.0013395907876325671 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-5654732 Negative regulation of FGFR3 signaling 4/197 29/10654 0.001874706892584716 0.004153091546711396 0.0013395907876325671 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-8863795 Downregulation of ERBB2 signaling 4/197 29/10654 0.001874706892584716 0.004153091546711396 0.0013395907876325671 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-8982491 Glycogen metabolism 4/197 29/10654 0.001874706892584716 0.004153091546711396 0.0013395907876325671 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-68949 Orc1 removal from chromatin 6/197 71/10654 0.0019557801740273132 0.0043169402386711965 0.001392440621508441 7316/9978/7311/5701/7314/6233 6 Tomato_spotted_wilt_virus R-HSA-9012852 Signaling by NOTCH3 5/197 49/10654 0.002024693600824972 0.004452858752538979 0.001436281501729385 7316/7311/7314/6233/2033 5 Tomato_spotted_wilt_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 4/197 30/10654 0.0021322032114655877 0.00467237310238127 0.0015070864424571511 7316/7311/7314/6233 4 Tomato_spotted_wilt_virus R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 5/197 50/10654 0.0022164373339126496 0.004839487272248124 0.0015609895649668793 7316/7311/5701/7314/6233 5 Vaccinia_virus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 297/3478 309/10654 9.123359872349033e-130 1.2635853423203411e-126 5.118685065223195e-127 8454/9354/57154/5718/197131/23352/5689/8945/10293/51088/140460/5684/79754/6737/8065/64410/127544/114088/5720/11065/285231/221687/9666/84937/142678/57531/55070/5682/84708/246184/146330/55819/51320/7319/54850/93611/142686/8916/79791/26046/151636/5700/122706/7321/5707/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/8697/7320/5690/26235/10477/9817/10193/148581/9039/223082/92912/154881/7174/26224/5717/140739/25897/9491/23198/6500/6478/150726/390594/10533/81559/143471/144699/5706/140462/5705/26259/57674/10197/53339/154214/7336/200845/79876/26263/64750/51619/6477/9690/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/10213/5709/9604/9978/22888/5695/23304/7317/80196/114907/140456/64718/54926/4008/7335/84861/11059/55236/84085/55958/54620/4734/84078/7337/5714/26272/84676/27252/51444/7704/8651/3093/26118/222235/51433/9861/25831/7322/5715/64219/10489/5711/23327/9867/26249/140458/55905/5701/5688/55336/5687/26270/143279/51465/63893/89122/6502/23291/118424/5685/10616/5683/5698/5708/27246/5692/5686/89910/5713/55521/25898/9903/201456/55294/5699/26190/55008/7328/79654/5710/10422/84727/135892/7428/5702/22954/8453/401036/83737/51529/9040/90933/140461/7324/63891/5719/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/5704/6233/90135/56658/9870/9520/51434/6468/26267/142685/5716/25847/90025/7327/10425/25793/51343/7311/26091/23295/6047/84541/7318/23194/51666/90293/131405/55175/55284/868/54461/9320/80204/136371/26232/29882/57520/26234/127247/27338/7334/92591/5930/11275/5694/55182/84961/4591/23014/29116/26268/92369/115290/7332/90678/51725/140459/5693/5721/5696/997/23608/51676/55585/64320/5691/51132/84261/7325/57542/9820/55658/7314/996/10324/283807/140691/899 297 Vaccinia_virus R-HSA-3700989 Transcriptional Regulation by TP53 331/3478 365/10654 7.508669245641737e-124 5.199753452606903e-121 2.1063793199616033e-121 23368/9377/6884/1017/23774/6875/834/6118/2176/5170/80010/27161/27113/5563/3725/9891/2963/9134/5434/5440/27165/4436/83990/8621/902/1329/83667/1353/1820/64769/7862/9156/3622/57060/5883/1763/7531/1029/7027/1459/25946/79370/7486/389541/9540/5430/10111/5457/8793/9219/6874/8445/7532/207/10971/5436/1345/55240/9997/22974/133383/9212/57690/835/204851/7832/4849/6878/1027/58484/4869/3486/5982/51422/7249/404672/27327/898/5931/355/58528/7295/4850/7533/2810/55367/1460/6749/4292/11200/116228/545/472/117584/53632/27244/5441/79813/8794/192670/7534/332/5438/153129/580/8550/5431/11073/7001/9337/5934/639/5435/64065/7316/1869/891/6872/28996/1351/116028/890/80196/2539/84289/1457/54971/4331/10769/983/1026/5433/54205/5366/6790/641/5933/6341/124446/5111/25904/1108/1643/8148/2966/8797/246175/5395/285521/64223/29117/4194/6879/9150/2962/84883/9656/5519/112858/4514/6119/1647/147923/5928/3364/5876/1432/143686/5571/10524/10848/1387/54457/4683/4848/10325/27154/56950/5437/8812/1350/144715/5458/83860/57459/23019/1616/9099/51499/843/2821/8649/28984/10000/6794/2965/5985/54815/51755/2877/2033/995/94241/1874/10128/84126/5728/25824/6009/900/8738/7994/905/2068/54541/1111/5439/192669/3066/3065/2071/7157/1107/8900/5984/91875/8626/6873/6827/5371/23112/1337/208/10498/10542/6233/5527/2968/1349/2475/55004/672/55571/5932/1025/2353/604/7311/63970/7161/839/6881/2967/5562/51616/5518/6834/1386/55835/10670/6880/6908/10419/4513/5325/8851/5300/7156/581/5983/4343/6117/1340/11198/50484/1327/5600/7159/57472/904/4697/9167/6883/3276/144455/85456/6829/79733/29883/26523/51497/5564/7874/51230/6882/5052/637/317/5565/1020/138474/133746/5608/5884/5810/64121/53615/10397/1022/8795/5432/665/57521/26155/26013/8178/5875/83695/10919/6877/7529/7296/7314/253260/28956/4193/5515/1263/27166/4512/5516 331 Vaccinia_virus R-HSA-983169 Class I MHC mediated antigen processing & presentation 320/3478 371/10654 1.4373893141436874e-105 6.635947333630024e-103 2.6881701910125804e-103 8454/9354/23643/57154/1147/5718/197131/23352/5689/8945/4688/10293/51088/140460/5684/79754/6737/8065/64410/127544/114088/5720/11065/285231/221687/9666/84937/142678/57531/55070/5682/84708/246184/146330/55819/51320/7319/54850/93611/142686/8916/79791/26046/151636/5700/122706/7321/5707/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/8697/10484/7320/5690/26235/10477/9817/10193/148581/9039/223082/92912/154881/7174/26224/5717/140739/25897/9491/23198/6500/6478/150726/390594/811/10533/81559/143471/144699/5706/140462/5705/26259/57674/10333/10197/7099/53339/8517/154214/7336/200845/4615/79876/26263/64750/51619/6477/9690/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/10213/5709/9604/9978/22888/5695/23304/7317/80196/114907/140456/22872/64718/54926/4008/7335/7096/84861/11059/55236/84085/55958/54620/4734/84078/7337/5714/26272/84676/27252/51444/7704/8651/3093/26118/222235/51433/9861/25831/7322/5715/64219/10489/5711/23327/9867/26249/140458/55905/5701/5688/10134/55336/5687/26270/143279/51465/63893/89122/6502/23291/118424/5685/10616/5683/929/3309/5698/5708/27246/5692/5686/89910/5713/55521/114609/25898/9903/201456/55294/5699/26190/55008/2923/7328/79654/5710/10422/84727/135892/7428/5702/22954/8453/401036/83737/51529/9040/695/90933/140461/7324/63891/5719/10075/64682/29945/9246/10393/79176/80176/9902/8139/8924/8925/51191/126433/5704/6233/90135/56658/9870/9520/51434/6468/26267/142685/5716/25847/90025/7327/3685/10425/25793/51343/7311/9871/26091/23295/6047/84541/7318/23194/51666/90293/131405/55175/55284/868/54461/9320/80204/136371/26232/29882/57520/26234/6396/127247/27338/7334/92591/5930/11275/5694/7097/55182/84961/4591/3551/23014/29116/26268/92369/115290/7332/90678/51725/140459/5693/5721/5696/997/23608/51676/55585/64320/5691/51132/84261/7325/57542/9820/55658/7314/996/10324/283807/140691/899 320 Vaccinia_virus R-HSA-8951664 Neddylation 214/3478 234/10654 2.40048370035659e-81 8.311674812484693e-79 3.3669942428685856e-79 8454/9318/5718/51397/5689/54165/8945/56995/23412/51088/9655/140460/5684/79754/8065/64410/5720/149951/29099/285231/11091/23363/5682/23038/146330/80344/54850/93611/142686/55884/79791/5700/122706/7321/5707/51665/9616/122769/9021/4738/5690/26235/9817/9039/154881/26224/5717/140739/5929/9491/23198/6500/5931/150726/3091/390594/143471/144699/5706/140462/28952/5705/26259/10197/53339/28991/200845/332/26263/140825/8452/8450/7323/9306/10517/89890/142689/7316/10213/5709/9978/5695/114907/140456/4008/84861/64708/84085/55958/54620/84078/5714/55527/26272/27252/7704/1643/10980/26118/222235/9861/7322/5715/122416/10489/5711/26249/140458/5701/5688/55336/5687/26270/1161/6502/7347/23291/170622/5685/90864/5683/55832/5698/5708/1642/5692/10920/5686/23113/5713/9903/201456/55294/5699/26190/10238/5710/84727/10987/7428/5702/8453/123879/401036/9040/140461/5719/79176/80176/8139/23142/126433/10116/5704/6233/90135/6468/2873/26267/142685/5716/25793/7311/1154/84541/23194/83987/51666/90293/55175/8533/54461/80204/136371/26232/8835/26234/127247/8883/92591/51667/11275/5694/51122/84961/54939/23014/26268/92369/115290/54951/51725/140459/5693/55208/5721/84259/5696/51676/5691/84261/150684/50813/57542/9820/7314/51514/10537/51138/10324/8451/56929/283807/899 214 Vaccinia_virus R-HSA-5663202 Diseases of signal transduction 284/3478 377/10654 4.8088071140715094e-67 1.332039570597808e-64 5.395987772210767e-65 5295/8454/4000/1147/5718/2308/27044/27123/5689/5170/2963/8805/5434/5440/7276/1839/5684/22906/4893/11052/6464/8841/685/5290/5720/3667/5335/71/79718/8087/79885/1487/142678/2309/5682/5291/5604/1499/2648/10018/9734/892/10142/55869/842/55750/5700/3815/122706/572/5707/283455/10956/5430/8844/23462/207/51564/3674/5436/7094/1452/5690/55534/5594/3280/2069/4303/84335/613/5717/1027/8074/9491/7249/182/23198/6500/409/5908/930/84441/7414/10533/55109/10013/143471/23385/5706/2064/5705/5441/23164/6199/10197/10046/54845/5438/5431/54518/6776/5528/2100/5435/84447/4686/7316/10213/5709/673/83933/9978/1950/9611/5695/3714/8546/6774/89780/54492/4233/9759/9612/102/1026/5433/1024/57085/5714/22866/6772/6714/2099/5605/4609/5664/7415/9861/64223/4089/10014/5715/2962/22938/5037/5519/9061/8850/8503/5711/399687/80853/2932/10256/2261/5701/867/5688/1387/5437/5159/5687/7046/3717/4088/10827/2247/5685/2244/6907/29851/3164/5683/5698/5708/5880/10000/3320/3084/145957/5692/5686/26508/5713/324/2335/2534/2033/9148/54894/3690/408/391/55294/5728/5699/6400/8312/1445/5710/2264/5439/5702/3066/3065/2280/2066/5894/4087/5719/6868/208/9794/6654/9542/5704/83464/6233/5527/2885/10718/2475/5716/2266/7409/56829/8660/1385/7048/23493/7311/8826/5906/9846/3932/2931/5518/2243/57534/7450/6469/1956/54567/11160/60/5296/1185/4140/7040/9444/3845/388585/55851/51107/6777/5694/3265/3516/369/801/9715/4763/5781/4851/5432/22916/5693/5663/5721/5696/11140/5691/5245/7529/5156/28514/7314/5879/57670/253260/5595/4193/5515/5516 284 Vaccinia_virus R-HSA-453279 Mitotic G1-G1/S phases 145/3478 149/10654 1.7640347564252676e-65 4.071980229414993e-63 1.6495272371485394e-63 8454/5718/1017/4172/6118/5689/25/894/9134/1019/5684/5000/5720/4605/902/8318/5682/23594/1029/7027/5700/5707/8317/207/5690/5717/1027/9491/6500/7153/898/54107/5925/4173/5706/5705/10197/4149/286826/91768/5934/5557/7316/10213/5709/5422/1869/4174/891/1875/5753/993/5695/890/1876/4331/983/1026/84515/5933/5714/5111/5426/6714/4171/4609/1871/9861/51053/1031/5715/5519/4998/6119/5711/5928/5701/5688/5687/91750/10926/5427/4067/3717/6502/5685/5683/5698/5708/10000/5692/5686/5713/990/1021/1874/595/5699/4175/5710/81620/5702/3065/5520/8900/896/5719/208/1870/5704/6233/7298/55388/29935/5716/1032/55957/1030/23595/7311/5518/23649/6117/1719/5001/5694/7465/1163/5558/1022/1859/5693/5721/5696/4999/7083/132660/5691/1028/4176/7314/5515/6241/5516/56655 145 Vaccinia_virus R-HSA-5663205 Infectious disease 285/3478 383/10654 3.0633861953628163e-65 6.061128400825001e-63 2.4553155520727536e-63 3839/6158/6884/928/5718/23165/3303/6875/5689/5905/6138/8945/1173/6144/2963/3837/3838/2237/6203/5434/5440/1839/5684/5903/6227/9349/8065/4736/7852/5720/902/6206/6194/6234/6191/55706/7175/162/6166/6128/5606/5682/51121/6132/9631/5604/1499/1938/3159/6147/6159/6129/6217/5700/3843/122706/5707/5430/6874/6230/6222/5436/6176/6152/5690/6136/2060/5045/7520/6878/6125/5717/4869/9491/23198/6500/404672/6749/811/6224/6146/6154/51065/348995/6141/9636/143471/6202/79023/5706/6123/5705/5441/57122/23636/10197/6232/5438/6134/3978/3981/6169/10762/5431/6160/23511/6164/5435/4686/7316/6155/10213/5709/1500/6175/9978/6218/5695/6872/53371/5611/920/292/4233/4331/5433/4836/9397/6209/5714/6193/6714/6173/23279/4927/6210/5605/6231/6229/9688/11224/8148/6205/2966/6165/8731/9861/79902/6130/6879/9150/5715/2962/6142/3840/6167/5711/6204/23327/9883/5701/867/5688/54457/6228/5437/8812/23521/5687/116832/29082/83860/8732/999/5685/5683/5698/5708/9146/3320/5692/2965/5686/128866/5713/6192/2534/140801/6156/5699/6235/905/6143/5710/2068/6181/5439/6124/5702/2071/5901/6207/8086/5478/6873/5719/6827/6139/5609/5704/6233/2885/23225/3326/2968/5716/7514/1025/9844/7311/6223/25873/9972/6881/2967/3932/51616/1213/5610/6880/6908/1211/3921/6188/6189/8021/7040/7251/11198/6396/6135/6201/129401/375/904/6161/6883/5694/3304/6829/1104/51497/2547/801/9045/6882/6187/6416/138474/5608/1022/5432/55746/6168/22916/5693/6208/1234/10254/6157/5721/6137/5696/8178/6170/5691/200916/8480/6122/6877/6133/291/7296/7314/5879 285 Vaccinia_virus R-HSA-194840 Rho GTPase cycle 136/3478 138/10654 5.493170893166267e-64 9.510052108794101e-62 3.852447481654764e-62 9181/57569/9639/9743/445328/64333/7984/55843/394/398/9912/57522/392/55789/57580/7204/29/64411/9938/257106/2909/10928/3633/27237/2245/389/55160/613/29127/84904/7074/9459/1894/388/11214/10451/116985/54509/89839/10276/23370/1124/116984/84144/6453/117289/58480/9828/9824/50650/4168/9754/221472/23263/84033/23229/55114/393/55288/50649/10144/79658/5881/9826/23092/4650/100271715/57636/9138/94134/143872/22899/115703/23365/1123/396/5880/85360/158763/57514/391/171177/57584/26230/9322/397/58504/23221/998/57449/51291/89941/2/6654/90627/83478/7410/7409/23433/4649/23380/51306/8997/57381/26084/29984/387/54848/6655/5296/8874/84986/389337/128272/121512/91614/25791/64857/55701/395/201176/5924/9411/2665/9886/93663/2664/89846/399/80728/5879/10395/4952/4983/9901/10672 136 Vaccinia_virus R-HSA-5633007 Regulation of TP53 Activity 151/3478 160/10654 2.0678031961831176e-62 3.182119363015131e-60 1.2890515831176628e-60 23368/6884/1017/23774/6875/6118/5170/80010/5563/9891/83990/64769/7862/9156/3622/5883/1763/1029/1459/25946/7486/10111/5457/9219/6874/8445/207/22974/133383/9212/204851/6878/5982/51422/5931/1460/6749/11200/545/472/117584/53632/79813/580/8550/11073/639/7316/6872/28996/116028/890/80196/84289/1457/54971/983/6790/641/1108/8148/64223/29117/4194/6879/5519/112858/6119/5928/3364/1432/5571/10524/10848/54457/4683/27154/56950/144715/5458/83860/57459/1616/9099/10000/6794/5985/54815/2033/94241/84126/900/7994/1111/3066/3065/7157/1107/8900/5984/91875/8626/6873/5371/208/6233/5527/2475/672/5932/7311/7161/6881/5562/51616/5518/6880/6908/10419/8851/5300/7156/5983/6117/11198/5600/7159/6883/5564/7874/51230/6882/5565/1020/138474/133746/5608/5884/5810/53615/26155/26013/83695/10919/6877/7314/253260/4193/5515/1263/5516 151 Vaccinia_virus R-HSA-69206 G1/S Transition 127/3478 131/10654 9.552969669747494e-57 1.323086299260028e-54 5.359718772605699e-55 8454/5718/1017/4172/6118/5689/9134/1019/5684/5000/5720/902/8318/5682/23594/7027/5700/5707/8317/207/5690/5717/1027/9491/6500/898/54107/5925/4173/5706/5705/10197/4149/286826/91768/5934/5557/7316/10213/5709/5422/1869/4174/891/1875/5753/993/5695/890/1876/4331/983/1026/84515/5933/5714/5111/5426/4171/4609/9861/51053/5715/5519/4998/6119/5711/5928/5701/5688/5687/91750/10926/5427/6502/5685/5683/5698/5708/10000/5692/5686/5713/990/1874/595/5699/4175/5710/81620/5702/3065/8900/5719/208/5704/6233/7298/55388/29935/5716/55957/23595/7311/5518/23649/6117/1719/5001/5694/7465/1163/5558/1022/5693/5721/5696/4999/7083/132660/5691/4176/7314/5515/6241/5516/56655 127 Vaccinia_virus R-HSA-69242 S Phase 147/3478 161/10654 1.0309408061063355e-55 1.2980481967793406e-53 5.25829138425528e-54 8454/5718/1017/4172/6118/5689/2237/9134/1019/5684/994/5000/5720/11065/902/8318/5682/246184/23594/1763/7027/5700/122706/7321/5707/207/8697/5690/5717/1027/5982/9491/23198/6500/898/54107/5925/23244/4173/143471/5706/5705/10197/4149/286826/3978/91768/8881/5934/5885/5557/7316/10213/5709/5422/9978/1869/4174/1875/5753/993/5695/890/4331/1026/84515/5714/5111/5426/4171/4609/51433/9861/5715/4998/6119/5711/5928/2932/5701/5688/5687/91750/5427/6502/5685/5683/5698/5708/10000/5692/5985/5686/5713/990/119504/1874/8243/9126/595/5699/4175/5710/81620/5702/8900/51529/5984/7324/5719/64682/29945/10393/208/5704/6233/51434/5716/55957/51343/23595/7311/25906/23649/157570/5983/6117/29882/5001/5981/5694/10714/7465/1163/5558/5424/1022/5693/5721/5696/4999/132660/5691/4176/7314/996/56655 147 Vaccinia_virus R-HSA-168255 Influenza Life Cycle 135/3478 144/10654 7.311826684139086e-55 8.439066631277195e-53 3.418599668987836e-53 6158/23165/3303/6138/6144/2963/3837/6203/5434/5440/5903/6227/9349/4736/6206/6194/6234/6191/55706/7175/6166/6128/51121/6132/9631/6147/6159/6129/6217/3843/5430/6230/6222/5436/6176/6152/6136/6125/811/6224/6146/6154/51065/348995/6141/6202/79023/6123/5441/57122/23636/6232/5438/6134/6169/10762/5431/6160/23511/6164/5435/6155/6175/6218/53371/5611/5433/6209/6193/6173/23279/4927/6210/6231/6229/9688/11224/6205/6165/79902/6130/2962/6142/6167/6204/9883/6228/5437/23521/116832/3320/6192/140801/6156/6235/6143/6181/5439/6124/5901/6207/8086/6139/6233/23225/7514/7311/6223/25873/9972/1213/1211/3921/6188/6189/8021/6396/6135/6201/129401/6161/3304/9045/6187/5432/55746/6168/6208/6157/6137/6170/200916/8480/6122/6133 135 Vaccinia_virus R-HSA-168273 Influenza Viral RNA Transcription and Replication 127/3478 134/10654 3.4255553902836176e-53 3.6495340119560077e-51 1.4783975894908243e-51 6158/23165/6138/6144/2963/6203/5434/5440/5903/6227/9349/4736/6206/6194/6234/6191/55706/7175/6166/6128/51121/6132/9631/6147/6159/6129/6217/3843/5430/6230/6222/5436/6176/6152/6136/6125/6224/6146/6154/51065/348995/6141/6202/79023/6123/5441/57122/23636/6232/5438/6134/6169/10762/5431/6160/23511/6164/5435/6155/6175/6218/53371/5611/5433/6209/6193/6173/23279/4927/6210/6231/6229/9688/11224/6205/6165/79902/6130/2962/6142/6167/6204/9883/6228/5437/23521/116832/3320/6192/140801/6156/6235/6143/6181/5439/6124/6207/8086/6139/6233/23225/7311/6223/25873/9972/3921/6188/6189/8021/6396/6135/6201/129401/6161/9045/6187/5432/55746/6168/6208/6157/6137/6170/200916/8480/6122/6133 127 Vaccinia_virus R-HSA-6807070 PTEN Regulation 131/3478 140/10654 5.496635246111883e-53 5.3278481767990375e-51 2.1582694875423805e-51 1912/5718/5689/27161/3725/6591/5684/8841/5720/5682/5468/1822/23186/1459/5700/122706/5707/2146/389541/5978/9112/9219/8535/10273/207/51564/6045/5690/57690/5594/84232/5717/9491/23198/27327/80012/5931/58528/1460/143471/5706/5705/10197/192670/153129/7316/10213/5709/5695/1457/1911/4734/5714/1108/57167/2122/11060/9861/7101/64223/10014/5715/5711/1958/5928/5701/5688/84733/10325/5687/57459/5685/8649/5683/5698/5708/10000/5692/54815/5686/5713/23512/57332/5728/5699/6009/2444/5710/6615/5702/192669/3066/3065/7157/1107/23028/5719/5987/5371/23112/208/10542/5704/6233/2475/5716/55004/57504/7311/1386/10670/331/4343/8726/648/5694/23466/26523/7874/64121/53615/57521/5693/5721/5696/23608/5691/7314/6015/28956/5595 131 Vaccinia_virus R-HSA-168254 Influenza Infection 141/3478 155/10654 5.770232682453832e-53 5.3278481767990375e-51 2.1582694875423805e-51 3839/6158/23165/3303/6138/6144/2963/3837/3838/6203/5434/5440/5903/6227/9349/4736/6206/6194/6234/6191/55706/7175/6166/6128/51121/6132/9631/6147/6159/6129/6217/3843/5430/6230/6222/5436/6176/6152/6136/6125/811/6224/6146/6154/51065/348995/6141/9636/6202/79023/6123/5441/57122/23636/6232/5438/6134/6169/10762/5431/6160/23511/6164/5435/6155/6175/6218/53371/5611/5433/6209/6193/6173/23279/4927/6210/6231/6229/9688/11224/6205/6165/79902/6130/2962/6142/3840/6167/6204/9883/6228/5437/23521/116832/3320/6192/140801/6156/6235/6143/6181/5439/6124/5901/6207/8086/6139/6233/23225/7514/7311/6223/25873/9972/1213/5610/1211/3921/6188/6189/8021/7040/6396/6135/6201/129401/6161/3304/9045/6187/5432/55746/6168/6208/6157/6137/6170/200916/8480/6122/6133 141 Vaccinia_virus R-HSA-9006925 Intracellular signaling by second messengers 227/3478 305/10654 6.34555073817893e-52 5.492867357736136e-50 2.225117462795638e-50 5295/1912/1147/5718/2308/5689/5170/27161/3725/23396/6591/3643/3838/1839/5684/8841/685/5290/5720/3667/5335/2309/5682/5291/5468/1822/23186/1459/842/5700/3815/122706/572/5707/5567/2146/389541/5978/9112/9219/8535/10273/207/51564/6045/5690/5578/57690/5594/2069/4303/84335/5568/84232/5717/1027/8074/9491/7249/5582/23198/27327/80012/930/5931/58528/1460/112/143471/114/5706/3708/2064/5705/8395/6199/10197/108/192670/4615/153129/5573/113/5528/2100/7316/10213/5709/1950/5695/111/107/1457/4233/1026/1911/4734/5714/6714/2099/1108/57167/2122/11060/9861/7101/64223/5566/10014/5715/5519/8503/5711/1958/5928/2932/2261/5701/5688/84733/10325/5159/5687/57459/5576/2247/5685/29851/8649/3164/5683/5698/5708/5880/10000/3084/145957/5692/54815/5686/5713/2534/23512/57332/391/5728/5699/6009/2444/5710/6615/2264/3630/5702/192669/3066/3065/7157/1107/2066/23028/5719/5987/3654/7189/5371/23112/208/9542/10542/5577/5704/6233/5527/2885/10718/5580/2475/5716/55004/7409/51135/8660/1385/57504/7311/3932/2931/5518/1386/10670/1956/5296/331/4343/8726/196883/8394/648/115/5694/23466/26523/7874/801/5781/64121/53615/57521/5693/5721/5696/23608/814/109/5691/5156/7314/5879/6015/253260/28956/5595/4193/5515/3556/5516 227 Vaccinia_virus R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 110/3478 112/10654 2.9608945067160295e-51 2.3367597219217382e-49 9.46603026246845e-50 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6147/6159/8666/6129/6217/6230/6222/1983/6176/6152/6136/8668/8667/6125/6224/6146/6154/51065/8662/6141/10480/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/6192/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968 110 Vaccinia_virus R-HSA-1257604 PIP3 activates AKT signaling 204/3478 264/10654 3.036944042930779e-51 2.3367597219217382e-49 9.46603026246845e-50 5295/1912/1147/5718/2308/5689/5170/27161/3725/23396/6591/3643/1839/5684/8841/685/5290/5720/3667/2309/5682/5291/5468/1822/23186/1459/842/5700/3815/122706/572/5707/2146/389541/5978/9112/9219/8535/10273/207/51564/6045/5690/57690/5594/2069/4303/84335/84232/5717/1027/8074/9491/7249/23198/27327/80012/930/5931/58528/1460/143471/5706/2064/5705/8395/6199/10197/192670/4615/153129/5528/2100/7316/10213/5709/1950/5695/1457/4233/1026/1911/4734/5714/6714/2099/1108/57167/2122/11060/9861/7101/64223/10014/5715/5519/8503/5711/1958/5928/2932/2261/5701/5688/84733/10325/5159/5687/57459/2247/5685/29851/8649/3164/5683/5698/5708/5880/10000/3084/145957/5692/54815/5686/5713/2534/23512/57332/391/5728/5699/6009/2444/5710/6615/2264/3630/5702/192669/3066/3065/7157/1107/2066/23028/5719/5987/3654/7189/5371/23112/208/9542/10542/5704/6233/5527/2885/10718/2475/5716/55004/7409/51135/8660/1385/57504/7311/3932/2931/5518/1386/10670/1956/5296/331/4343/8726/8394/648/5694/23466/26523/7874/5781/64121/53615/57521/5693/5721/5696/23608/5691/5156/7314/5879/6015/253260/28956/5595/4193/5515/3556/5516 204 Vaccinia_virus R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 109/3478 111/10654 9.101129208648769e-51 6.634244186304497e-49 2.6874802593960076e-49 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6147/6159/8666/6129/6217/6230/6222/6176/6152/6136/8668/8667/6125/6224/6146/6154/51065/8662/6141/10480/26986/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/6192/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968 109 Vaccinia_virus R-HSA-73887 Death Receptor Signalling 130/3478 141/10654 1.35696831614989e-50 9.397005589337988e-49 3.806653223725744e-49 9181/7124/1147/25999/4804/9639/57142/445328/8841/7984/7186/4790/6885/5584/10018/7531/572/8737/57580/7204/29/8767/8793/55072/356/4974/7375/27237/2245/55160/835/8878/84904/7074/9459/1894/355/11214/330/23118/10451/23385/10276/841/27005/23370/8517/4615/8887/9500/6453/7316/9828/50650/5970/4792/4168/65078/8439/221472/23263/84033/5664/23229/8797/50649/9826/7128/7132/100271715/329/9138/84894/9099/843/22899/836/23365/10616/396/8837/4803/26230/11108/10454/3066/3065/8567/57449/3654/7189/6868/6654/4099/83464/6233/7410/7409/7311/8997/26574/26084/387/54848/6655/8772/331/8874/389337/5599/128272/8717/55851/51107/121512/1540/25791/3551/7185/64857/8743/55701/8795/5924/5663/89846/7314/5879/257397/10672 130 Vaccinia_virus R-HSA-376176 Signaling by ROBO receptors 177/3478 218/10654 3.2122313954241264e-50 2.1185430869821023e-48 8.582051798301049e-49 6158/5718/5689/6138/6144/1287/25/55740/6203/5684/6227/9349/4736/7852/5720/6206/6194/6234/6191/9423/6166/6128/5682/51121/6132/57522/2817/6147/6159/10298/6129/4690/6217/5700/122706/5707/5567/6230/6222/6176/6152/5690/6136/5578/5532/5568/6125/5717/9353/9491/23198/6224/6146/6154/51065/6141/26986/143471/6202/5706/6123/5705/10197/6232/6134/6169/6160/6091/55110/22794/6164/4686/7316/6155/10213/5709/6175/9978/6218/5695/4116/5216/6209/5714/6193/6714/6173/6210/6231/6229/11224/6205/6165/9861/5566/6130/5715/6142/6167/5711/6204/4650/5701/5688/6228/23521/5687/116832/5576/5685/5683/5698/5708/51466/5692/5686/5713/6192/1981/7408/140801/6156/5699/6235/6143/5710/6181/6124/5702/998/8453/6207/5719/6139/10487/6654/5704/6233/5716/23380/7311/6223/25873/387/1630/6655/3921/6188/6189/9775/5217/6135/6201/6161/5694/5058/9045/6187/6168/22916/5693/6208/6157/5721/6137/5696/6170/5691/4440/200916/6122/80728/6133/7314/5879/6387/9901 177 Vaccinia_virus R-HSA-69306 DNA Replication 120/3478 127/10654 6.979755708335924e-50 4.3940734800205704e-48 1.7800046854272955e-48 8454/5718/1017/4172/6118/5689/2237/9134/5684/5000/5720/11065/8318/5682/246184/23594/1763/5700/122706/7321/5707/8317/8697/5690/5717/5982/9491/23198/6500/898/54107/4173/143471/5706/5705/10197/3978/8881/5557/7316/10213/5709/5422/9978/1869/4174/5695/890/84515/5714/5111/5426/4171/1871/51433/9861/51053/5715/4998/6119/5711/5701/5688/5687/10926/5427/6502/5685/5683/5698/5708/5692/5985/5686/5713/990/119504/5699/4175/5710/81620/5702/8900/51529/5984/7324/5719/64682/29945/10393/1870/5704/6233/51434/55388/29935/5716/51343/23595/7311/25906/23649/5983/6117/29882/5001/5981/5694/10714/5558/5424/5693/5721/5696/4999/5691/4176/7314/996/56655 120 Vaccinia_virus R-HSA-8957275 Post-translational protein phosphorylation 106/3478 108/10654 2.637290734015588e-49 1.5881076811354738e-47 6.433299593731388e-48 56955/4240/3371/3270/351/9210/8720/10272/7018/2153/4052/10618/54587/11167/7184/7857/56975/813/5179/401138/3486/8074/7425/51246/29106/6383/91851/3912/348/3827/3490/338/6696/64856/4924/51156/3484/335/5589/5611/2621/1435/102/3915/8614/5768/1471/1462/6694/265/4148/10232/462/197/11098/3053/3698/174/57104/721/10130/5265/2335/1758/3895/334/2200/258/5624/80341/7466/375056/1000/54757/11320/8404/255738/3913/5954/652/116519/2266/51280/57719/7076/147111/2243/1114/84141/213/2719/720/10117/3956/336/3569/10970/3488/8542/54972/5034/3487/1356/2519/4221/718 106 Vaccinia_virus R-HSA-194315 Signaling by Rho GTPases 294/3478 455/10654 3.1390755845559633e-46 1.811508201920837e-44 7.338277572668107e-45 9181/85415/3831/57569/26999/5170/5905/9639/11130/84617/4688/25/9743/445328/5590/64333/5903/1072/3984/7984/55843/394/398/64837/9912/71/5579/4638/57522/1495/1499/392/7531/5747/4690/1783/1058/4659/55789/991/1856/10006/57580/7204/29/64411/9938/257106/4627/51807/2316/7532/2909/10928/10971/3633/27237/10458/4771/10382/2245/5578/9212/389/55160/5594/3985/54763/6722/613/29127/84904/3798/7074/1027/9459/10627/1894/388/11214/1080/7533/2810/7277/348995/10451/55920/79023/116985/54509/10381/57122/79980/89839/10276/23370/30851/1124/7278/116984/6232/7534/94274/332/112714/1780/84144/6242/5528/6453/3688/5048/117289/58480/9828/5501/9824/10398/8655/50650/4085/5289/5585/5216/4168/9754/221472/81624/10094/10152/6279/23263/6714/84033/23279/23229/55114/393/79902/55288/50649/3796/10144/79658/5881/1730/5519/9826/23092/4650/1432/100271715/4637/57636/9138/699/94134/143872/7846/22899/115703/999/113457/89953/23365/1123/396/347733/5880/51466/22919/85360/79784/9475/158763/995/3895/57514/10376/391/23002/171177/57584/26230/9322/11113/397/58504/23221/51143/998/4628/23028/695/57449/51291/89941/2/1742/6654/90627/8976/5527/1855/83478/2885/7410/5580/7454/701/10097/9055/7409/1857/23433/4649/23191/7514/6093/23380/51306/57120/9928/8997/367/8826/147700/10499/29941/5518/57381/3799/26084/10383/103910/29984/5347/387/1729/54848/6655/60/5296/5300/84790/114822/8874/84986/389337/5217/6396/128272/5600/10095/121512/91614/25791/5058/801/3071/64857/55701/10109/395/5586/55746/201176/5924/9411/2665/4660/140735/9886/93663/7280/2664/4629/89846/5500/399/7529/80728/5879/10395/4952/4221/5595/64130/4983/5515/1778/9901/5516/10672 294 Vaccinia_virus R-HSA-69239 Synthesis of DNA 112/3478 119/10654 4.060150529308492e-46 2.0827068455897265e-44 8.436881996574761e-45 8454/5718/1017/4172/6118/5689/2237/9134/5684/5000/5720/11065/8318/5682/246184/23594/1763/5700/122706/7321/5707/8697/5690/5717/5982/9491/23198/6500/898/54107/4173/143471/5706/5705/10197/3978/8881/5557/7316/10213/5709/5422/9978/4174/5695/890/84515/5714/5111/5426/4171/51433/9861/5715/4998/6119/5711/5701/5688/5687/5427/6502/5685/5683/5698/5708/5692/5985/5686/5713/990/119504/5699/4175/5710/81620/5702/8900/51529/5984/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/23595/7311/25906/23649/5983/6117/29882/5001/5981/5694/10714/5558/5424/5693/5721/5696/4999/5691/4176/7314/996/56655 112 Vaccinia_virus R-HSA-72613 Eukaryotic Translation Initiation 112/3478 119/10654 4.060150529308492e-46 2.0827068455897265e-44 8.436881996574761e-45 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6147/6159/8666/6129/6217/6230/6222/1983/6176/6152/6136/8668/8667/6125/6224/6146/6154/51065/8662/6141/10480/26986/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/6192/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/1978/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968 112 Vaccinia_virus R-HSA-72737 Cap-dependent Translation Initiation 112/3478 119/10654 4.060150529308492e-46 2.0827068455897265e-44 8.436881996574761e-45 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/51121/6132/6147/6159/8666/6129/6217/6230/6222/1983/6176/6152/6136/8668/8667/6125/6224/6146/6154/51065/8662/6141/10480/26986/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/8663/6228/23521/116832/8894/6192/1981/140801/6156/6235/6143/1973/6181/6124/6207/1977/6139/6233/1975/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/1978/6161/9045/6187/6168/6208/6157/6137/6170/1974/200916/6122/6133/1968 112 Vaccinia_virus R-HSA-72689 Formation of a pool of free 40S subunits 99/3478 101/10654 6.712711117381033e-46 3.3203946062759754e-44 1.3450657990842446e-44 6158/8669/6138/6144/6203/6227/9349/4736/6206/6194/6234/27335/6191/6166/6128/51121/6132/6147/6159/8666/6129/6217/6230/6222/6176/6152/6136/8668/8667/6125/6224/6146/6154/51065/8662/6141/10480/6202/6123/6232/6134/6169/6160/6164/6155/8661/6175/6218/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/8663/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/8664/3646/51386/3921/6188/6189/8665/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133 99 Vaccinia_virus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 145/3478 171/10654 8.221071994060713e-46 3.926270590266927e-44 1.590501405747499e-44 6158/5718/5689/6138/6144/1287/6203/5684/6227/9349/4736/5720/6206/6194/6234/6191/6166/6128/5682/51121/6132/6147/6159/6129/6217/5700/122706/5707/6230/6222/6176/6152/5690/6136/6125/5717/9353/9491/23198/6224/6146/6154/51065/6141/26986/143471/6202/5706/6123/5705/10197/6232/6134/6169/6160/6091/55110/22794/6164/4686/7316/6155/10213/5709/6175/9978/6218/5695/4116/6209/5714/6193/6173/6210/6231/6229/11224/6205/6165/9861/6130/5715/6142/6167/5711/6204/5701/5688/6228/23521/5687/116832/5685/5683/5698/5708/5692/5686/5713/6192/1981/140801/6156/5699/6235/6143/5710/6181/6124/5702/8453/6207/5719/6139/5704/6233/5716/7311/6223/25873/3921/6188/6189/9775/6135/6201/6161/5694/9045/6187/6168/22916/5693/6208/6157/5721/6137/5696/6170/5691/4440/200916/6122/6133/7314 145 Vaccinia_virus R-HSA-449147 Signaling by Interleukins 294/3478 461/10654 1.5774210509756826e-44 7.282427185337734e-43 2.950054105859785e-43 5295/729230/8454/3605/3557/7124/1147/5718/2308/834/5689/3725/7291/5777/8945/596/9655/5684/5601/351/1072/6464/5290/5720/3667/1441/4790/6627/6885/6597/5606/2309/5682/5291/5604/1511/3561/5657/11213/3587/5783/7412/5700/6351/122706/7184/5707/27250/10392/27178/8767/356/3593/6775/207/3684/9021/7422/29110/5690/3553/2625/1230/5594/8878/3595/54472/6624/4582/5717/2919/9491/23198/6500/5908/5743/3091/1265/23118/143471/4318/5706/4312/3383/5705/246330/301/9987/11009/6097/10197/4478/8517/6657/6778/3576/4615/7534/3313/332/6776/5528/3688/2357/1436/4313/7316/3565/58480/4985/10213/5709/6175/9978/2920/3560/5695/79155/6352/3185/6774/920/1435/7335/5970/4792/5443/6850/1026/59307/3718/1440/4793/3627/5714/6772/8651/8809/4609/3146/6647/9861/5566/149233/5715/5519/5898/64127/8503/5711/7132/4988/5598/1901/3552/1432/5701/867/2889/5688/79923/5687/466/6950/4067/3558/3717/23291/4088/3636/598/2247/836/5685/5683/5698/5708/3320/5602/5692/5686/200081/5713/4843/2335/2534/3656/595/6195/5699/57162/5710/3458/3181/10454/6288/5702/998/7157/6648/5478/5719/3654/7189/6285/5609/6654/5704/6233/2885/7525/1398/6364/3716/5716/85480/7409/51135/8660/1385/2353/604/6196/7311/3594/1154/6363/6809/9846/6347/3932/3575/7076/6888/5518/2185/302/1386/6382/6655/5296/7040/6935/3687/51561/3570/6197/8835/5599/5600/7431/4282/375/6777/7334/5008/5694/3312/1399/3559/3551/6773/7297/6416/5781/5608/3569/3162/57161/1278/4170/5693/3689/1234/5721/5696/3601/3586/5691/4791/3554/5034/51231/4692/7314/3572/1846/3596/5595/5515/257397/3598/3556/5516 294 Vaccinia_virus R-HSA-418594 G alpha (i) signalling events 267/3478 406/10654 4.284257962096391e-44 1.9140958959688714e-42 7.753852270958834e-43 2788/729230/151/57007/10316/10803/2913/4544/4543/126006/4889/3838/1880/7276/26086/9283/727/351/11251/7852/5321/9294/54331/3352/8484/50833/29899/338398/5726/117579/283869/338442/2817/59345/63940/4986/375790/23566/6351/2358/5567/2916/64805/2770/6752/259293/2781/6374/1237/5539/259287/1903/2852/2550/84539/5578/50836/1230/5532/5594/50832/5179/3354/6753/846/5568/2841/4886/2919/3577/2918/5582/4987/51289/10681/80835/5368/6754/8862/51764/259294/112/94235/114/3708/259290/301/6383/8811/2912/108/3576/56670/5196/6360/5573/348/3827/2775/150/113/338/5173/56923/3579/2832/5530/5528/2357/4985/27199/2920/335/2826/55970/2921/2778/1236/2853/6352/140/6751/6376/259295/165140/27198/111/107/5443/6010/9568/4836/186/3627/53637/2792/9397/54429/346562/6714/2840/2831/3361/6346/152/5566/5367/80834/10563/5519/134/5540/4988/259292/1901/6370/58191/2793/5030/5697/6755/5576/1524/5733/256933/10663/1129/643/10850/51083/2785/3355/5534/2783/624/3351/2784/4852/2782/1233/6288/6372/6366/2786/5499/50834/339403/2861/259285/2771/728/50838/5577/2914/183/10022/5473/4283/6364/5580/8843/1385/5144/719/2847/6363/2359/6373/57121/2917/2833/1268/9290/11255/50831/5518/9170/6382/187/1132/10874/1814/50839/83756/4036/6357/196883/6750/115/259296/2719/8698/259289/56477/5660/50835/801/1815/2587/336/1325/53829/1020/1232/9934/50840/1902/259286/3350/129521/1234/50837/2791/814/109/1269/59340/50865/4887/2773/2790/5515/718/2787/6387/623/5516 267 Vaccinia_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 91/3478 92/10654 1.6106854948784202e-43 6.971248157520663e-42 2.8239979235861775e-42 6884/1017/6875/6118/80010/5563/9891/83990/9156/5883/1763/1459/7486/10111/6874/8445/22974/9212/204851/6878/5982/51422/1460/6749/11200/545/472/53632/580/8550/11073/7316/6872/28996/116028/890/1457/6790/641/8148/4194/6879/112858/6119/3364/1432/5571/10524/54457/4683/144715/83860/6794/5985/94241/84126/1111/7157/8900/5984/6873/6233/672/5932/7311/6881/5562/51616/6880/6908/8851/5300/7156/5983/6117/11198/5600/6883/5564/6882/5565/1020/138474/5884/5810/26155/83695/6877/7314/4193/1263 91 Vaccinia_virus R-HSA-69052 Switching of origins to a post-replicative state 89/3478 90/10654 1.5314990319910577e-42 6.427655028204893e-41 2.6037926126036165e-41 8454/5718/1017/4172/5689/9134/5684/5000/5720/11065/5682/246184/23594/5700/122706/7321/5707/8697/5690/5717/9491/23198/6500/898/4173/143471/5706/5705/10197/8881/7316/10213/5709/9978/4174/5695/890/84515/5714/4171/51433/9861/5715/4998/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/990/119504/5699/4175/5710/81620/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/23595/7311/25906/29882/5001/5694/5693/5721/5696/4999/5691/4176/7314/996 89 Vaccinia_virus R-HSA-193704 p75 NTR receptor-mediated signalling 94/3478 97/10654 3.966658435262388e-42 1.6158299802465905e-40 6.545600451996449e-41 9181/4804/9639/57142/445328/8841/7984/4790/5584/10018/7531/572/57580/7204/29/8767/4974/27237/2245/55160/835/8878/84904/7074/9459/1894/11214/10451/23385/10276/23370/4615/9500/6453/7316/9828/50650/5970/4792/4168/65078/221472/23263/84033/5664/23229/50649/9826/100271715/9138/84894/22899/836/23365/396/4803/26230/11108/3066/3065/57449/3654/7189/6868/6654/4099/83464/6233/7410/7409/7311/8997/26574/26084/387/54848/6655/8874/389337/5599/128272/55851/51107/121512/25791/3551/64857/55701/5924/5663/89846/7314/5879/10672 94 Vaccinia_virus R-HSA-2262752 Cellular responses to stress 296/3478 479/10654 7.17845001239753e-41 2.840615219191594e-39 1.1507109343181605e-39 1912/5718/1017/23165/3303/7014/6118/5689/3725/84617/4688/25913/9134/1019/5684/5903/5601/5720/11065/573/83667/4790/55706/7175/5241/5606/5682/9631/3159/246184/112399/7531/7290/1029/7027/1915/1783/5700/122706/7321/5707/2146/389541/10111/8535/51807/6045/9550/7422/8697/5690/10382/57690/5594/3308/84335/5717/1027/9491/23198/27327/80012/898/10049/5931/58528/7295/10294/5925/55860/3091/7277/348995/1051/1410/10013/143471/545/79023/5706/472/27244/10381/5705/57122/23636/79813/10197/3337/192670/3576/7278/3313/153129/112714/1780/10762/3490/8550/8881/7001/29855/23511/7323/7316/10213/5709/9978/2114/1869/5695/890/10935/3305/53371/8655/6774/5970/1026/1911/9532/54205/832/6667/5714/9588/23279/4927/9688/7415/1871/6647/8994/51433/9861/79902/64223/4194/1031/7322/91582/5715/6119/5711/5598/9883/3552/5928/10370/1432/2932/5701/10524/5688/1387/84733/4683/10325/5687/57805/7846/112398/3310/113457/2908/5685/8649/5683/3309/5698/347733/5708/3320/5602/5692/5686/5713/2877/2033/23512/1021/119504/7266/57332/10376/6195/5699/25824/6009/5710/6767/25842/51143/3301/7428/5702/192669/10540/9531/7157/8453/8900/51529/6648/8086/23135/7324/5719/64682/29945/10393/8091/23112/5609/8131/1870/10542/5704/6233/2056/51434/23225/3326/2475/5716/55004/1032/3306/2353/1030/51343/6196/7311/367/9972/538/25906/3397/57634/10383/10670/23411/84790/8021/9529/4343/8726/55662/6117/6197/29882/5599/6396/648/129401/5600/5694/3304/3312/23466/4217/26523/3456/528/5052/2113/405/6416/5608/3569/64121/57521/55746/5693/5721/140735/5696/7280/2288/5691/5034/8480/10919/768/10728/7296/7314/23523/996/6015/28956/5595/4193/2950/9296/1778 296 Vaccinia_virus R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 112/3478 125/10654 1.1302227265929428e-40 4.3482179898089605e-39 1.761428986181399e-39 56955/4240/3371/3270/351/9210/8720/10272/7018/2153/4052/1511/5340/10618/54587/11167/7184/7857/56975/813/5179/401138/3486/8074/7425/4312/51246/29106/6383/91851/3912/348/3827/3490/338/6696/64856/4924/51156/4313/3484/335/5589/5611/2621/1435/102/3915/8614/5768/1471/1462/6694/265/4148/10232/462/197/11098/3053/3698/174/57104/721/10130/5265/2335/1758/3895/334/2200/258/5624/80341/7466/375056/1000/54757/3481/11320/8404/255738/3913/5954/652/116519/2266/51280/57719/7076/3479/147111/2243/1114/84141/213/2719/720/10117/3956/336/3569/10970/3488/8542/54972/5034/3487/1356/2519/4221/718 112 Vaccinia_virus R-HSA-156842 Eukaryotic Translation Elongation 90/3478 93/10654 3.3024275108456142e-40 1.2361789466273448e-38 5.007663906915255e-39 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/1917/1938/6147/6159/6129/1915/6217/1936/6230/6222/6176/6152/6136/6125/1937/6224/6146/6154/51065/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133 90 Vaccinia_virus R-HSA-69002 DNA Replication Pre-Initiation 84/3478 85/10654 4.245310953066201e-40 1.547304123683339e-38 6.268007584444003e-39 5718/1017/4172/6118/5689/5684/5000/5720/8318/5682/23594/5700/122706/5707/8317/5690/5717/9491/23198/54107/4173/143471/5706/5705/10197/5557/7316/10213/5709/5422/1869/4174/5695/84515/5714/5426/4171/1871/9861/51053/5715/4998/6119/5711/5701/5688/5687/10926/5427/5685/5683/5698/5708/5692/5686/5713/990/5699/4175/5710/81620/5702/5719/1870/5704/6233/55388/29935/5716/23595/7311/23649/6117/5001/5694/5558/5693/5721/5696/4999/5691/4176/7314/56655 84 Vaccinia_virus R-HSA-156902 Peptide chain elongation 87/3478 89/10654 4.418474143982656e-40 1.5691247921579433e-38 6.3564014001154e-39 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/1938/6147/6159/6129/1915/6217/6230/6222/6176/6152/6136/6125/6224/6146/6154/51065/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133 87 Vaccinia_virus R-HSA-5357801 Programmed Cell Death 145/3478 181/10654 5.882935996995091e-40 2.03696658895955e-38 8.251591806311536e-39 23368/23643/4000/5718/1828/5689/2934/27113/11035/3837/596/5684/5720/7186/1612/5682/1499/10018/7531/5747/1029/7027/842/5700/122706/572/5707/8737/356/7532/207/10971/5690/5594/10059/5717/9491/23198/63967/355/330/7533/2810/143471/5706/1829/5705/841/10197/7099/7534/100506658/9500/7316/10213/5709/1869/5695/8655/7082/6774/54205/5339/4836/5366/5714/5317/8797/3146/9861/5715/79658/5711/5701/5688/10134/329/90249/5687/1832/999/598/56616/836/5685/5683/929/5698/5708/10000/5692/5686/5713/324/8837/5534/5699/4137/5710/3002/5702/7157/90427/8626/5719/1830/197259/208/5704/6233/5580/6709/5716/6093/1613/7311/7161/839/840/1630/8772/331/581/5599/353376/8717/7159/7431/5694/26060/637/317/8743/8795/5693/5721/140735/5696/3148/5691/7529/7314/578/5595/148022 145 Vaccinia_virus R-HSA-109581 Apoptosis 142/3478 178/10654 9.3595750297689e-39 3.1617101015194945e-37 1.28078395144206e-37 23368/23643/4000/5718/1828/5689/2934/27113/3837/596/5684/5720/7186/1612/5682/1499/10018/7531/5747/1029/7027/842/5700/122706/572/5707/8737/356/7532/207/10971/5690/5594/10059/5717/9491/23198/63967/355/7533/2810/143471/5706/1829/5705/841/10197/7099/7534/100506658/9500/7316/10213/5709/1869/5695/8655/7082/6774/54205/5339/4836/5366/5714/5317/8797/3146/9861/5715/79658/5711/5701/5688/10134/329/90249/5687/1832/999/598/56616/836/5685/5683/929/5698/5708/10000/5692/5686/5713/324/8837/5534/5699/4137/5710/3002/5702/7157/90427/8626/5719/1830/208/5704/6233/5580/6709/5716/6093/1613/7311/7161/839/840/1630/8772/331/581/5599/353376/8717/7159/7431/5694/26060/637/317/8743/8795/5693/5721/140735/5696/3148/5691/7529/7314/578/5595/148022 142 Vaccinia_virus R-HSA-9013694 Signaling by NOTCH4 81/3478 82/10654 1.235491477317821e-38 4.074180228774243e-37 1.650418439625059e-37 8454/5718/5689/5684/5720/5682/2648/5700/5707/23462/207/5690/55534/3280/5717/9491/182/6500/84441/23385/5706/5705/10197/10460/10046/7534/7316/10213/5709/9978/5695/102/5714/5664/9861/5715/22938/8850/5711/5701/5688/1387/5687/4088/5685/5683/5698/5708/59/5692/5686/5713/2033/4855/55294/5699/5710/4853/5702/5719/9794/5704/83464/6233/2324/5716/23493/7311/54567/388585/55851/51107/5694/3516/4851/5693/5663/5721/5696/5691/7314 81 Vaccinia_virus R-HSA-8953897 Cellular responses to external stimuli 298/3478 493/10654 1.7507140280321405e-38 5.6389277414523596e-37 2.284285378068864e-37 1912/5718/1017/23165/3303/7014/6118/5689/3725/84617/4688/25913/9134/1019/5684/5903/5601/5720/11065/573/83667/4790/55706/7175/5241/5606/5682/9631/3159/246184/112399/7531/7290/1029/7027/1915/1783/5700/122706/7321/5707/2146/389541/10111/8535/51807/6045/9550/7422/8697/5690/10382/57690/5594/3308/84335/5717/1027/9491/23198/27327/80012/898/10049/5931/58528/7295/10294/5925/55860/3091/7277/348995/1051/1410/10013/143471/545/79023/5706/472/27244/10381/5705/57122/23636/79813/10197/3337/192670/3576/7278/3313/153129/112714/1780/10762/3490/8550/8881/7001/29855/23511/7323/7316/10213/5709/9978/2114/1869/5695/890/10935/3305/53371/8655/6774/5970/1026/1911/9532/54205/832/6667/5714/9588/23279/4927/9688/7415/1871/6647/8994/51433/9861/79902/64223/4194/1031/7322/91582/5715/4493/6119/5711/5598/9883/3552/5928/10370/1432/2932/5701/10524/5688/1387/84733/4683/10325/5687/57805/7846/112398/3310/113457/2908/5685/8649/5683/3309/5698/347733/5708/3320/5602/5692/5686/5713/2877/2033/23512/1021/119504/7266/57332/10376/6195/5699/25824/6009/5710/6767/25842/51143/3301/7428/5702/192669/10540/9531/7157/8453/8900/51529/6648/8086/23135/7324/5719/64682/29945/10393/8091/23112/5609/8131/1870/10542/5704/6233/2056/51434/23225/3326/2475/5716/55004/1032/3306/2353/1030/51343/6196/7311/367/9972/538/25906/3397/57634/10383/10670/23411/84790/8021/9529/4343/8726/55662/6117/4520/6197/29882/5599/6396/648/129401/5600/5694/3304/3312/23466/4217/26523/3456/528/5052/2113/405/6416/5608/3569/64121/57521/55746/5693/5721/140735/5696/7280/2288/5691/5034/8480/10919/768/10728/7296/7314/23523/996/6015/28956/5595/4193/2950/9296/1778 298 Vaccinia_virus R-HSA-192823 Viral mRNA Translation 86/3478 89/10654 2.7252746281363324e-38 8.57842127265641e-37 3.4750511406618788e-37 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6147/6159/6129/6217/6230/6222/6176/6152/6136/6125/6224/6146/6154/51065/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/5611/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133 86 Vaccinia_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 83/3478 85/10654 3.7898619521372096e-38 1.1664352897133412e-36 4.725137825705573e-37 8454/5718/1017/5689/9134/1019/5684/994/5720/902/5682/7027/5700/5707/207/5690/5717/1027/9491/6500/898/5925/5706/5705/10197/4149/286826/91768/5934/7316/10213/5709/1869/1875/5753/993/5695/890/4331/1026/5714/4609/9861/5715/5711/5928/5701/5688/5687/91750/6502/5685/5683/5698/5708/10000/5692/5686/5713/1874/595/5699/5710/5702/8900/5719/208/5704/6233/5716/55957/51343/7311/5694/7465/1163/1022/5693/5721/5696/132660/5691/7314 83 Vaccinia_virus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 90/3478 95/10654 6.87394965024503e-38 2.0696565794759493e-36 8.384016392632952e-37 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6147/6159/6129/6217/6230/6222/6176/6152/6136/6125/6224/6146/6154/51065/6141/26986/6202/6123/6232/6134/6169/6160/6164/4686/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/1981/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/5976/6187/6168/22916/6208/6157/6137/6170/200916/6122/6133 90 Vaccinia_virus R-HSA-69202 Cyclin E associated events during G1/S transition 81/3478 83/10654 3.4999932821825493e-37 1.0313809991112407e-35 4.178043492504588e-36 8454/5718/1017/5689/9134/1019/5684/5720/902/5682/7027/5700/5707/207/5690/5717/1027/9491/6500/898/5925/5706/5705/10197/4149/286826/91768/5934/7316/10213/5709/1869/1875/5753/993/5695/890/4331/1026/5714/4609/9861/5715/5711/5928/5701/5688/5687/91750/6502/5685/5683/5698/5708/10000/5692/5686/5713/1874/595/5699/5710/5702/8900/5719/208/5704/6233/5716/55957/7311/5694/7465/1163/1022/5693/5721/5696/132660/5691/7314 81 Vaccinia_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 114/3478 134/10654 1.6879920728823803e-36 4.870560460296035e-35 1.9730258220313786e-35 5295/8454/1147/5718/5689/5170/3725/8945/5684/5601/4893/6464/4773/5290/5720/5335/4790/6885/5682/5291/4772/5700/122706/7321/5707/3937/5336/84433/5690/5532/5594/4775/5717/4214/9491/23198/6500/23118/10892/143471/10451/5706/3708/5705/10197/8517/5530/7316/10213/5709/5695/7335/5970/4792/6850/8915/5714/9861/7322/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5602/5692/5686/5713/2534/5534/5699/5710/10454/5702/695/5719/7189/5609/6654/5704/6233/2885/7410/5716/7409/3702/2353/7311/9846/5296/3845/5599/7334/5694/3265/3551/5058/801/6416/5693/5721/5696/997/5691/7314/5879/5595/257397 114 Vaccinia_virus R-HSA-1980143 Signaling by NOTCH1 73/3478 73/10654 1.9299360583879878e-36 5.455023348708904e-35 2.2097871517095542e-35 8454/8841/7090/79718/79885/142678/2648/9734/892/55869/23462/51564/113878/55534/3280/23220/182/6500/409/84441/3091/10013/23385/10046/7316/83933/9978/9611/3714/7091/8650/54492/1272/9759/9612/102/1024/4609/5664/10014/22938/8850/1387/8788/6907/26508/2033/9148/408/55294/3066/3065/7088/83737/92737/6868/9794/83464/6233/23493/7311/1840/57534/54567/7089/388585/55851/51107/3516/4851/5663/28514/7314 73 Vaccinia_virus R-HSA-9020702 Interleukin-1 signaling 94/3478 103/10654 6.845062099173637e-36 1.8960822014710975e-34 7.680880208125366e-35 8454/3557/1147/5718/5689/8945/5684/351/5720/4790/6885/5682/5604/11213/5700/122706/5707/10392/8767/5690/3553/8878/54472/5717/9491/23198/6500/23118/143471/5706/5705/246330/10197/8517/4615/7316/10213/5709/9978/5695/79155/7335/5970/4792/4793/5714/3146/9861/5715/64127/5711/3552/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/3656/5699/57162/5710/10454/6288/5702/5719/3654/7189/6285/5704/6233/5716/51135/7311/7334/5694/3551/6416/5608/57161/5693/5721/5696/5691/4791/3554/7314/257397/3556 94 Vaccinia_virus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 82/3478 86/10654 3.2700188718327475e-35 8.709569495169914e-34 3.5281782564511224e-34 8454/5718/1017/5689/8945/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/9212/5717/9491/23198/6500/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/8556/7324/5719/64682/29945/10393/9232/5704/6233/51434/5716/701/51343/7311/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 82 Vaccinia_virus R-HSA-453276 Regulation of mitotic cell cycle 82/3478 86/10654 3.2700188718327475e-35 8.709569495169914e-34 3.5281782564511224e-34 8454/5718/1017/5689/8945/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/9212/5717/9491/23198/6500/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/8556/7324/5719/64682/29945/10393/9232/5704/6233/51434/5716/701/51343/7311/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 82 Vaccinia_virus R-HSA-162906 HIV Infection 166/3478 233/10654 3.902804928072712e-34 1.0198839293171143e-32 4.131469764970716e-33 6884/5718/23165/6875/5689/5905/8945/1173/2963/3837/2237/5434/5440/5684/5903/8065/7852/5720/902/55706/7175/162/5682/9631/3159/5700/122706/5707/5430/6874/5436/5690/5045/7520/6878/5717/4869/9491/23198/6500/404672/6749/348995/143471/79023/5706/5705/5441/57122/23636/10197/5438/3978/3981/10762/5431/23511/5435/4686/7316/10213/5709/9978/5695/6872/53371/920/292/4331/5433/4836/9397/5714/23279/4927/9688/8148/2966/8731/9861/79902/6879/9150/5715/2962/5711/23327/9883/5701/5688/54457/5437/8812/5687/29082/83860/8732/5685/5683/5698/5708/5692/2965/5686/128866/5713/2534/5699/905/5710/2068/5439/5702/2071/5901/8086/5478/6873/5719/6827/5704/6233/23225/2968/5716/7514/1025/9844/7311/9972/6881/2967/3932/51616/6880/6908/8021/7251/11198/6396/129401/375/904/6883/5694/6829/1104/51497/2547/6882/138474/1022/5432/55746/22916/5693/1234/5721/5696/8178/5691/8480/6877/291/7314/5879 166 Vaccinia_virus R-HSA-157118 Signaling by NOTCH 167/3478 235/10654 4.1060461351752825e-34 1.0531247957810678e-32 4.266125906527145e-33 8454/5718/1999/5689/27161/3725/23129/5684/8841/4242/5720/7090/79718/79885/142678/5682/23509/5584/2648/9734/892/7027/55869/5700/5707/23462/207/51564/4904/487/113878/5690/55534/5045/57690/3280/23220/5717/9491/182/6500/27327/409/84441/3091/51548/10013/23385/5706/3955/5705/10402/10197/10460/10046/192670/7534/488/7316/10213/5709/83933/9978/1950/1869/4854/9611/5695/3714/7091/8650/5986/54492/1272/9759/9612/102/6484/1024/5714/6772/4609/5664/10320/11060/1871/9861/10014/5715/5870/22938/8850/5711/489/5701/5688/1387/5687/8788/4088/2173/5685/6907/5683/5698/5708/59/5692/5686/26508/5713/2033/9148/408/4855/595/55294/5699/6400/5710/3002/4853/5702/192669/3066/3065/7157/7088/83737/861/5719/92737/6868/2683/23112/9794/5704/83464/6233/2324/5716/1385/56983/23493/7311/6487/1840/57534/1956/54567/7089/4343/388585/55851/51107/5694/26523/3516/4851/5693/5663/5721/5696/10959/5691/28514/7314 167 Vaccinia_virus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 77/3478 80/10654 5.4011763162121855e-34 1.3601143996279778e-32 5.509716701514057e-33 8454/5718/1017/5689/8945/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/6500/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/701/51343/7311/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 77 Vaccinia_virus R-HSA-204998 Cell death signalling via NRAGE, NRIF and NADE 74/3478 76/10654 8.246051195058783e-34 2.039425161635074e-32 8.261551291290097e-33 9181/4804/9639/445328/7984/10018/7531/572/57580/7204/29/27237/2245/55160/835/8878/84904/7074/9459/1894/11214/10451/23385/10276/23370/9500/6453/7316/9828/50650/4168/221472/23263/84033/5664/23229/50649/9826/100271715/9138/22899/836/23365/4803/26230/57449/7189/6654/83464/6233/7410/7409/7311/8997/26574/26084/54848/6655/8874/389337/5599/128272/55851/51107/121512/25791/64857/55701/5924/5663/89846/7314/5879/10672 74 Vaccinia_virus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 71/3478 72/10654 9.152994858616523e-34 2.1856720481351526e-32 8.85398595216444e-33 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/9212/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/6790/5714/51433/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/9232/5704/6233/51434/5716/51343/7311/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 71 Vaccinia_virus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 71/3478 72/10654 9.152994858616523e-34 2.1856720481351526e-32 8.85398595216444e-33 5718/1017/5689/9134/5684/5720/11065/5682/246184/5700/122706/7321/5707/8697/5690/5717/9491/23198/898/143471/5706/5705/10197/8881/7316/10213/5709/5695/890/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/990/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 71 Vaccinia_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 91/3478 101/10654 1.0847549019552654e-33 2.546416168149225e-32 1.0315332073901097e-32 8454/1147/5718/5689/5170/8945/5684/4773/5720/4790/6885/5682/4772/5700/122706/7321/5707/5336/84433/5690/3553/5532/9039/4775/5717/9491/23198/6500/23118/10892/29108/143471/5706/3708/5705/841/10197/8517/5530/7316/10213/5709/5695/9020/7335/5970/4792/6850/8915/5714/6714/9861/7322/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5534/5699/5710/10454/5702/9040/5719/7189/5704/6233/5580/5716/7311/7334/5694/3551/801/5693/5721/5696/997/5691/4791/7314/257397 91 Vaccinia_virus R-HSA-68949 Orc1 removal from chromatin 70/3478 71/10654 2.8031039054845426e-33 6.470498181826819e-32 2.621148037935546e-32 8454/5718/1017/4172/5689/5684/5000/5720/5682/23594/5700/122706/5707/5690/5717/9491/23198/6500/4173/143471/5706/5705/10197/7316/10213/5709/9978/4174/5695/890/84515/5714/4171/9861/5715/4998/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/990/5699/4175/5710/81620/5702/8900/5719/5704/6233/5716/23595/7311/5001/5694/5693/5721/5696/4999/5691/4176/7314 70 Vaccinia_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 278/3478 473/10654 6.95139071774767e-33 1.5783075646033645e-31 6.393600090698029e-32 5295/54106/255631/3675/26999/5170/1286/5777/627/1173/4688/1287/2963/3643/5434/5440/5800/1282/5590/1839/4893/8065/6464/685/85301/857/5290/3667/85440/5335/71/5899/558/5241/5579/5770/5291/1495/5604/1499/2904/5340/6461/5747/4690/3815/5567/10006/1299/5430/10048/10273/207/5436/256076/10019/9550/7422/1284/10458/2060/5578/5045/5594/10193/2069/5568/7074/8074/3315/5908/3178/10817/23118/51741/10451/23385/4318/3708/2064/382/5921/5441/1277/1280/1289/6778/3912/54845/5438/348/5431/6696/6776/5528/9306/5435/3688/1793/4686/7316/673/1500/1950/5753/9611/51072/9047/3185/1298/6774/11059/5289/4233/102/5433/4734/3915/1301/10413/10152/5046/6772/6714/2099/8651/5605/5664/3910/64223/5566/8569/2962/1281/1297/1290/5519/5898/1003/8503/5598/1432/2261/867/2889/5437/5159/466/4670/2567/4067/3717/2321/2247/4914/10000/9146/3320/3084/145957/2335/2534/9475/3690/4846/6195/3728/4803/8471/1445/1111/2264/5439/5603/3630/998/2066/83737/3481/6868/7072/3913/3925/6285/208/1742/6654/9542/83464/6233/2885/7525/1398/5867/3187/10718/7410/5580/2324/2475/7409/5900/8660/23191/6093/1385/3685/9844/6196/7311/1292/5906/9846/57610/3932/3479/1759/5518/2185/1213/3791/387/1729/1956/1211/50509/60/8851/29924/5296/1293/581/8874/9564/6197/3845/1285/5600/55851/51107/131873/6777/3265/1399/5058/6300/528/801/3071/1020/5781/7057/5432/1278/3480/22916/5663/2591/10254/5725/11140/1302/51231/1291/7529/5156/63916/5829/7314/1846/5879/253260/5595/9296/5515/6387/5516/5607 278 Vaccinia_virus R-HSA-69620 Cell Cycle Checkpoints 194/3478 293/10654 9.350677083514703e-33 2.069278290511702e-31 8.382483973724014e-32 5718/1017/4172/6118/5689/5905/80010/11130/9134/5684/5903/5000/5720/83990/11065/8318/5682/9156/57060/246184/23594/5883/1763/7531/51512/1029/25946/1783/1058/5700/7486/122706/7321/5707/991/10111/7532/8317/10971/8697/5690/9212/51588/51720/5717/1027/5982/9491/23198/63967/898/7533/2810/348995/4173/11200/143471/545/55920/79023/5706/9133/472/5705/57122/79980/10197/7336/6232/7534/332/580/1780/8881/11073/29086/5528/5048/7316/10213/5709/4174/891/993/5695/5501/116028/890/8655/4085/983/1026/84515/641/5714/4171/23279/51433/9861/79902/4194/3796/5715/9656/5519/4998/6119/5711/3364/7341/5701/10524/5688/4683/699/5687/10926/144715/5685/5683/5698/5708/5692/22919/5985/5686/5713/990/995/119504/165918/84126/5699/4175/5710/51143/1111/5702/7157/8900/51529/5984/7324/5719/64682/29945/10393/8924/5704/6233/5527/51434/55388/5716/701/672/7514/5932/7158/23595/7311/9025/79184/5518/25906/5347/7156/5983/6117/29882/6396/7334/5001/5694/7465/51230/5884/5810/55746/5693/5721/140735/5696/4999/83695/5691/4176/7529/7314/996/4193/5515/1778/5516 194 Vaccinia_virus R-HSA-927802 Nonsense-Mediated Decay (NMD) 99/3478 115/10654 9.562007985036022e-33 2.069278290511702e-31 8.382483973724014e-32 6158/9887/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6147/6159/6129/6217/6230/6222/6176/6152/6136/6125/6224/6146/6154/51065/6141/26986/6202/6123/6232/6134/6169/6160/55110/22794/6164/4686/6155/6175/6218/4116/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/1981/140801/6156/6235/6143/6181/6124/5520/6207/6139/6233/23381/7311/6223/25873/5518/3921/6188/6189/9775/6135/6201/6161/9045/5976/6187/6168/22916/6208/6157/6137/6170/200916/6122/6133/5515 99 Vaccinia_virus R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 99/3478 115/10654 9.562007985036022e-33 2.069278290511702e-31 8.382483973724014e-32 6158/9887/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6147/6159/6129/6217/6230/6222/6176/6152/6136/6125/6224/6146/6154/51065/6141/26986/6202/6123/6232/6134/6169/6160/55110/22794/6164/4686/6155/6175/6218/4116/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/1981/140801/6156/6235/6143/6181/6124/5520/6207/6139/6233/23381/7311/6223/25873/5518/3921/6188/6189/9775/6135/6201/6161/9045/5976/6187/6168/22916/6208/6157/6137/6170/200916/6122/6133/5515 99 Vaccinia_virus R-HSA-2408557 Selenocysteine synthesis 85/3478 93/10654 1.1285215153101583e-32 2.368185301067529e-31 9.593332817548874e-32 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6147/6159/6129/6217/6230/6222/6176/6152/6136/6125/6224/6146/6154/51065/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133 85 Vaccinia_virus R-HSA-72764 Eukaryotic Translation Termination 85/3478 93/10654 1.1285215153101583e-32 2.368185301067529e-31 9.593332817548874e-32 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6147/6159/6129/6217/6230/6222/6176/6152/6136/6125/6224/6146/6154/51065/6141/6202/6123/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133 85 Vaccinia_virus R-HSA-416482 G alpha (12/13) signalling events 76/3478 80/10654 2.2065176893021506e-32 4.561234327885789e-31 1.8477202331469696e-31 2788/9181/9639/445328/7984/54331/59345/57580/7204/29/27237/2245/389/55160/84904/7074/9459/1894/10681/388/11214/51764/94235/10451/10276/5364/23370/6453/55970/9828/50650/4168/221472/2792/23263/84033/23229/50649/9826/100271715/9138/2793/22899/23365/9475/2785/2783/26230/2784/2768/2782/695/2786/57449/6654/7410/7409/6093/8997/26084/387/54848/6655/8874/389337/128272/121512/25791/64857/55701/5924/2791/89846/2790/2787/10672 76 Vaccinia_virus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 73/3478 76/10654 4.314083366234742e-32 8.786772738581056e-31 3.5594526845249497e-31 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/9232/5704/6233/51434/5716/701/7311/25906/5347/29882/5694/5693/5721/5696/5691/7314/996 73 Vaccinia_virus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 70/3478 72/10654 6.887625859228817e-32 1.3825162050770885e-30 5.600464657465994e-31 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/890/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/701/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 70 Vaccinia_virus R-HSA-68867 Assembly of the pre-replicative complex 67/3478 68/10654 8.032101467767499e-32 1.589208647551141e-30 6.43775952228583e-31 5718/4172/5689/5684/5000/5720/5682/23594/5700/122706/5707/5690/5717/9491/23198/4173/143471/5706/5705/10197/7316/10213/5709/1869/4174/5695/84515/5714/4171/1871/9861/51053/5715/4998/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/990/5699/4175/5710/81620/5702/5719/1870/5704/6233/5716/23595/7311/5001/5694/5693/5721/5696/4999/5691/4176/7314 67 Vaccinia_virus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 72/3478 75/10654 1.28740566470007e-31 2.511347669872672e-30 1.0173272339290395e-30 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/891/5695/890/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/9232/5704/6233/51434/5716/701/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 72 Vaccinia_virus R-HSA-8878159 Transcriptional regulation by RUNX3 86/3478 96/10654 1.870353551368293e-31 3.5978328731181745e-30 1.4574538638586259e-30 7004/57154/5718/5689/8463/51176/5684/5720/2309/5682/1499/2648/10018/1029/864/5700/5707/5690/55534/3280/5717/9491/182/84441/5706/5705/6097/10197/10046/64750/6696/7316/10213/5709/865/5695/9759/1026/10413/5714/6714/4609/9861/4089/5715/22938/8850/5711/5701/5688/1387/5687/4088/5685/5683/5698/5708/5692/5686/5713/2033/595/5699/5710/5702/7157/861/5719/9794/5704/6233/5716/7311/25937/7040/3845/5694/3516/4851/5693/5721/5696/5691/3676/7314/4193 86 Vaccinia_virus R-HSA-69481 G2/M Checkpoints 128/3478 168/10654 2.3762005073743686e-31 4.5082708256349324e-30 1.8262651340022185e-30 5718/1017/4172/6118/5689/80010/5684/5000/5720/83990/8318/5682/9156/23594/5883/1763/7531/51512/5700/7486/122706/5707/10111/7532/8317/10971/5690/51588/51720/5717/5982/9491/23198/63967/7533/2810/4173/11200/143471/545/5706/9133/472/5705/10197/7336/7534/580/11073/29086/7316/10213/5709/4174/891/993/5695/116028/983/84515/641/5714/4171/9861/5715/9656/4998/6119/5711/3364/7341/5701/10524/5688/4683/5687/10926/144715/5685/5683/5698/5708/5692/5985/5686/5713/990/995/165918/84126/5699/4175/5710/1111/5702/7157/5984/5719/8924/5704/6233/55388/5716/672/5932/7158/23595/7311/9025/79184/7156/5983/6117/7334/5001/5694/7465/5884/5810/5693/5721/5696/4999/83695/5691/4176/7529/7314 128 Vaccinia_virus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 66/3478 67/10654 2.4558670791040777e-31 4.596453925079929e-30 1.8619874155938457e-30 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/9232/5704/6233/51434/5716/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 66 Vaccinia_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 77/3478 83/10654 7.89042433132352e-31 1.4445661276605994e-29 5.8518240246482956e-30 8454/1147/5718/5689/8945/5684/4893/4773/5720/4790/6885/5579/5966/5682/4772/5700/122706/5707/84433/5690/5532/4775/5717/9491/23198/6500/10892/143471/5706/5705/10197/8517/5530/7316/10213/5709/5695/5970/4792/4793/8915/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5534/5699/5710/5702/2280/5478/5719/5704/6233/5716/7311/3845/5694/3265/3551/801/5693/5721/5696/5691/7314 77 Vaccinia_virus R-HSA-5628897 TP53 Regulates Metabolic Genes 79/3478 86/10654 7.926861061531087e-31 1.4445661276605994e-29 5.8518240246482956e-30 9377/27161/5563/27165/1329/83667/1353/7531/389541/7532/207/10971/1345/9997/57690/51422/7249/27327/58528/7295/7533/2810/116228/53632/27244/192670/7534/153129/7001/1351/2539/54205/6341/285521/64223/4514/143686/5571/10325/1350/2821/8649/10000/2877/10128/5728/25824/6009/54541/192669/7157/8626/23112/1337/208/10542/1349/2475/55004/5562/6834/10670/4513/4343/1340/50484/1327/4697/9167/26523/5564/5052/5565/64121/57521/7529/7296/28956/4512 79 Vaccinia_virus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 70/3478 73/10654 1.143929318633385e-30 2.0575871510483614e-29 8.335124085189257e-30 5718/5689/5684/5720/11065/5682/246184/5700/122706/7321/5707/991/8697/5690/5717/9491/23198/143471/5706/5705/10197/8881/7316/10213/5709/5695/890/4085/983/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/8900/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/701/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 70 Vaccinia_virus R-HSA-69615 G1/S DNA Damage Checkpoints 66/3478 68/10654 5.6993545845904085e-30 1.0120007820073995e-28 4.099535753828189e-29 5718/1017/5689/9134/5684/5720/5682/57060/1029/25946/5700/122706/5707/5690/5717/1027/9491/23198/898/11200/143471/5706/472/5705/10197/7316/10213/5709/993/5695/890/1026/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/7157/8900/5719/5704/6233/5716/7311/5694/51230/5693/5721/5696/5691/7314/4193 66 Vaccinia_virus R-HSA-193648 NRAGE signals death through JNK 59/3478 59/10654 1.4798294115066232e-29 2.5943844746033836e-28 1.0509647919160963e-28 9181/4804/9639/445328/7984/10018/572/57580/7204/29/27237/2245/55160/84904/7074/9459/1894/11214/10451/10276/23370/9500/6453/9828/50650/4168/221472/23263/84033/23229/50649/9826/100271715/9138/22899/23365/4803/26230/57449/6654/7410/7409/8997/26574/26084/54848/6655/8874/389337/5599/128272/121512/25791/64857/55701/5924/89846/5879/10672 59 Vaccinia_virus R-HSA-1169091 Activation of NF-kappaB in B cells 65/3478 67/10654 1.716297332098165e-29 2.971339756194948e-28 1.2036664184320024e-28 8454/1147/5718/5689/8945/5684/5720/4790/6885/5579/5966/5682/5700/122706/5707/84433/5690/5717/9491/23198/6500/10892/143471/5706/5705/10197/8517/7316/10213/5709/5695/5970/4792/4793/8915/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/3551/5693/5721/5696/5691/7314 65 Vaccinia_virus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 72/3478 77/10654 1.754861150094531e-29 3.000595917136945e-28 1.2155178596496232e-28 5718/5689/84617/5684/5720/5682/51512/5700/122706/5707/51807/5690/10382/5717/9491/23198/7277/143471/5706/9133/10381/5705/10197/7278/112714/7316/10213/5709/891/5695/983/1026/5714/9861/5715/5711/5701/5688/5687/7846/113457/5685/5683/5698/347733/5708/3320/5692/22919/5686/5713/10376/5699/5710/5702/7157/5719/5704/6233/3326/5716/7311/10383/5347/84790/5694/5693/5721/5696/7280/5691/7314 72 Vaccinia_virus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 62/3478 63/10654 2.1372834049770394e-29 3.609923799869756e-28 1.4623518034053427e-28 5718/5689/5684/5720/11065/5682/246184/5700/7321/5707/8697/5690/5717/9491/5706/5705/10197/8881/7316/10213/5709/5695/5714/51433/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/119504/5699/5710/5702/51529/7324/5719/64682/29945/10393/5704/6233/51434/5716/51343/7311/25906/29882/5694/5693/5721/5696/5691/7314/996 62 Vaccinia_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 58/3478 58/10654 4.5848749837205343e-29 7.298910175233265e-28 2.956731235720562e-28 8454/8841/79718/79885/142678/2648/9734/892/55869/23462/51564/55534/3280/182/6500/84441/10013/23385/10046/7316/83933/9978/9611/3714/54492/9759/9612/102/1024/4609/5664/10014/22938/8850/1387/6907/26508/2033/9148/55294/3066/3065/6868/9794/83464/6233/23493/7311/57534/54567/388585/55851/51107/3516/4851/5663/28514/7314 58 Vaccinia_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 58/3478 58/10654 4.5848749837205343e-29 7.298910175233265e-28 2.956731235720562e-28 8454/8841/79718/79885/142678/2648/9734/892/55869/23462/51564/55534/3280/182/6500/84441/10013/23385/10046/7316/83933/9978/9611/3714/54492/9759/9612/102/1024/4609/5664/10014/22938/8850/1387/6907/26508/2033/9148/55294/3066/3065/6868/9794/83464/6233/23493/7311/57534/54567/388585/55851/51107/3516/4851/5663/28514/7314 58 Vaccinia_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 58/3478 58/10654 4.5848749837205343e-29 7.298910175233265e-28 2.956731235720562e-28 8454/8841/79718/79885/142678/2648/9734/892/55869/23462/51564/55534/3280/182/6500/84441/10013/23385/10046/7316/83933/9978/9611/3714/54492/9759/9612/102/1024/4609/5664/10014/22938/8850/1387/6907/26508/2033/9148/55294/3066/3065/6868/9794/83464/6233/23493/7311/57534/54567/388585/55851/51107/3516/4851/5663/28514/7314 58 Vaccinia_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 58/3478 58/10654 4.5848749837205343e-29 7.298910175233265e-28 2.956731235720562e-28 8454/8841/79718/79885/142678/2648/9734/892/55869/23462/51564/55534/3280/182/6500/84441/10013/23385/10046/7316/83933/9978/9611/3714/54492/9759/9612/102/1024/4609/5664/10014/22938/8850/1387/6907/26508/2033/9148/55294/3066/3065/6868/9794/83464/6233/23493/7311/57534/54567/388585/55851/51107/3516/4851/5663/28514/7314 58 Vaccinia_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 58/3478 58/10654 4.5848749837205343e-29 7.298910175233265e-28 2.956731235720562e-28 8454/8841/79718/79885/142678/2648/9734/892/55869/23462/51564/55534/3280/182/6500/84441/10013/23385/10046/7316/83933/9978/9611/3714/54492/9759/9612/102/1024/4609/5664/10014/22938/8850/1387/6907/26508/2033/9148/55294/3066/3065/6868/9794/83464/6233/23493/7311/57534/54567/388585/55851/51107/3516/4851/5663/28514/7314 58 Vaccinia_virus R-HSA-8878166 Transcriptional regulation by RUNX2 99/3478 121/10654 4.99194362848942e-29 7.856638551656644e-28 3.182662624383805e-28 8454/57154/5718/8493/5689/7291/25/1019/5684/8841/5720/6662/5682/5700/122706/5707/23462/10273/207/5690/5594/3280/5717/9491/23198/6500/4086/5925/10013/143471/3958/5706/5705/3678/1277/10197/7316/10213/5709/9978/891/865/5695/4094/11059/9759/983/1026/10413/5714/6772/6714/2099/9861/4089/5715/5711/2932/5701/5688/5687/6502/650/2908/5685/5683/5698/5708/10000/5692/5686/5713/595/55294/5699/5710/5702/861/5719/208/5704/6233/7525/5716/23493/7311/25937/367/860/581/5694/5693/5721/5696/5691/117581/10891/7314/5595 99 Vaccinia_virus R-HSA-69563 p53-Dependent G1 DNA Damage Response 64/3478 66/10654 5.165110625709717e-29 7.9485313517866205e-28 3.2198876766120227e-28 5718/1017/5689/9134/5684/5720/5682/57060/1029/25946/5700/122706/5707/5690/5717/1027/9491/23198/898/11200/143471/5706/472/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/8900/5719/5704/6233/5716/7311/5694/51230/5693/5721/5696/5691/7314/4193 64 Vaccinia_virus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 64/3478 66/10654 5.165110625709717e-29 7.9485313517866205e-28 3.2198876766120227e-28 5718/1017/5689/9134/5684/5720/5682/57060/1029/25946/5700/122706/5707/5690/5717/1027/9491/23198/898/11200/143471/5706/472/5705/10197/7316/10213/5709/5695/890/1026/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/8900/5719/5704/6233/5716/7311/5694/51230/5693/5721/5696/5691/7314/4193 64 Vaccinia_virus R-HSA-5688426 Deubiquitination 188/3478 297/10654 5.111075790319729e-28 7.778945021530576e-27 3.151189585009156e-27 9960/5718/23358/5689/5684/8295/5720/3607/10617/221937/7186/645836/6885/5682/2648/79594/5700/10474/122706/7321/5707/991/51377/8737/10392/83444/8767/8237/4738/7375/5690/55611/2625/9817/57506/4303/100287364/51720/5717/9491/57646/23198/63967/409/6478/4086/1080/330/3091/143471/5706/100287513/5705/57695/11274/4287/27005/10197/7706/8517/86/64750/580/7416/29086/8239/7316/10213/5709/993/5695/29761/79155/890/7417/25862/4792/9738/9986/983/8314/84132/5714/4092/8678/2099/9100/1643/79589/4609/7415/392188/9861/55288/4194/23586/4089/5715/100287144/100287441/64127/8850/7128/5711/5701/5688/9097/329/5687/7046/6502/7347/9099/4088/5685/5683/5698/5708/9146/5692/5686/5713/324/2033/100287478/408/55777/64135/5728/5699/8724/8312/5710/10454/8473/100287327/5702/219333/7157/8900/9958/4087/63891/5719/7189/57599/5704/6233/377630/5716/672/7048/7311/55593/84282/367/6881/79184/51616/114548/78990/7187/387/10318/60/23770/7040/728386/5887/7345/3054/1540/5694/7874/100287404/5693/154/10254/5721/100287178/5696/5691/5886/100287205/7314/4193/100287238/7528 188 Vaccinia_virus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 59/3478 60/10654 6.061490214027627e-28 9.125178202639416e-27 3.6965380824676495e-27 8454/5718/1017/5689/9134/1019/5684/5720/5682/5700/5707/5690/5717/1027/9491/6500/898/5706/5705/10197/7316/10213/5709/5753/5695/890/1026/5714/9861/5715/5711/5701/5688/5687/6502/5685/5683/5698/5708/5692/5686/5713/595/5699/5710/5702/8900/5719/5704/6233/5716/7311/5694/1163/5693/5721/5696/5691/7314 59 Vaccinia_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 102/3478 129/10654 1.5004380317164856e-27 2.2345233052982072e-26 9.051878561458822e-27 8454/23643/1147/3665/23098/3725/11035/8945/5601/351/4790/6885/5606/5604/11213/7321/8737/10392/8767/5336/3684/29110/5594/4214/6500/330/23118/246330/10333/841/7099/8517/4615/5528/7323/7316/79155/7335/5970/4792/7096/59307/4793/8651/3146/7322/5519/64127/5598/1432/329/466/23291/929/5602/114609/3656/6195/57162/10454/6288/3661/695/3654/7189/6285/5609/6233/10010/51135/1385/2353/6196/7311/1759/5518/1386/7187/8772/9641/6197/5599/353376/5600/7334/7097/3551/6416/5781/5608/57161/3689/4791/51231/671/7314/1846/5595/5515/148022/257397/5516 102 Vaccinia_virus R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 58/3478 59/10654 1.8467751817212566e-27 2.6924038175620425e-26 1.0906716585677892e-26 5718/5689/5684/5000/5720/5682/23594/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/84515/5714/9861/51053/5715/4998/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/990/5699/5710/81620/5702/5719/5704/6233/5716/23595/7311/5001/5694/5693/5721/5696/4999/5691/7314 58 Vaccinia_virus R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 58/3478 59/10654 1.8467751817212566e-27 2.6924038175620425e-26 1.0906716585677892e-26 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6230/6222/8668/8667/6224/51065/8662/10480/26986/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/6192/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/8665/6201/1978/6187/6208/1974/1968 58 Vaccinia_virus R-HSA-446652 Interleukin-1 family signaling 108/3478 140/10654 1.9518370128643206e-27 2.815931523767796e-26 1.1407117630007487e-26 8454/3557/1147/5718/834/5689/5777/8945/5684/351/5720/4790/6885/5682/5604/1511/11213/5783/5700/122706/5707/10392/27178/8767/29110/5690/3553/8878/54472/5717/9491/23198/6500/23118/143471/5706/5705/246330/10197/8517/4615/7316/3565/10213/5709/9978/5695/79155/6774/7335/5970/4792/59307/4793/5714/8809/3146/9861/5715/64127/5711/3552/5701/5688/5687/23291/4088/5685/5683/5698/5708/5692/5686/5713/3656/5699/57162/5710/10454/6288/5702/5719/3654/7189/6285/5704/6233/5716/51135/7311/5599/7334/5694/3551/6416/5781/5608/57161/5693/5721/5696/5691/4791/3554/7314/3596/257397/3556 108 Vaccinia_virus R-HSA-168898 Toll-like Receptor Cascades 116/3478 155/10654 2.658407542266965e-27 3.795767470144069e-26 1.5376356158744356e-26 54106/8454/23643/1147/3665/23098/3725/11035/8945/5601/351/81793/4790/6885/5606/5604/11213/7184/7321/8737/10392/8767/5336/3684/29110/5594/4214/6500/8411/330/23118/246330/10333/841/7099/8517/4615/7098/7100/338/5528/7323/7316/79155/7335/5970/4792/7096/5289/59307/4793/6279/8651/3146/7322/5519/64127/5598/1432/329/466/23291/2244/929/5602/114609/3656/6195/57162/10454/6288/3661/695/3654/7189/6285/5609/6233/51311/10010/2266/51135/1385/2353/6196/7311/1759/5518/2243/1386/7187/8772/9641/6197/5599/353376/5600/7334/7097/3551/6416/5781/5608/57161/3689/4791/51231/671/51284/7314/1846/5595/5515/148022/257397/5516 116 Vaccinia_virus R-HSA-3858494 Beta-catenin independent WNT signaling 111/3478 146/10654 3.402347699514691e-27 4.80841996308964e-26 1.9478531942441787e-26 2788/57154/5718/5689/27161/51176/1173/5684/5720/54331/6885/5579/5682/1499/59345/51701/4772/5700/122706/5707/1856/5690/1212/5578/5532/57690/5717/9491/5582/50855/23198/10681/27327/409/51764/94235/143471/5706/7471/3708/5705/10197/192670/64750/2775/5530/7316/10213/5709/5695/55970/54361/5216/2792/5714/9861/5715/5881/5711/5701/5688/2793/5687/5685/5683/5698/5708/5880/5692/5686/5713/2785/5534/5699/2783/23002/2784/5710/2782/5702/192669/2786/5719/23112/5704/6233/1855/7474/5716/1857/7311/1213/387/1211/4343/5593/3845/5694/26523/801/5693/5721/2791/5696/6259/5691/7314/5879/2790/2787/5592 111 Vaccinia_virus R-HSA-5687128 MAPK6/MAPK4 signaling 78/3478 89/10654 3.636804806289794e-27 5.0878531885973386e-26 2.0610494011190434e-26 5718/2308/5689/27161/3725/5684/5720/2309/5682/5700/10642/122706/5707/5567/5690/57690/5568/5717/9491/3315/23198/27327/143471/5706/5705/10197/3337/192670/8550/7316/10213/5709/5695/983/5597/5714/4609/9861/5566/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/8555/5702/192669/998/8556/896/5719/23112/5704/6233/5716/7514/7311/8997/4343/5694/26523/5058/8202/5693/5721/5696/5691/7314/5879 78 Vaccinia_virus R-HSA-453274 Mitotic G2-G2/M phases 138/3478 198/10654 5.4918536096512615e-27 7.606217249366997e-26 3.0812189199411817e-026 10844/8454/115106/5718/1017/5689/8945/22995/84617/5684/994/5720/4605/902/2305/5682/22981/7531/51512/10142/4659/5700/11190/122706/5707/203068/51807/7532/1454/22974/5690/10382/3161/5717/9491/23198/6500/7277/143471/5706/9133/10381/5705/10197/7278/286826/112714/5048/7316/10213/5709/9978/1869/891/993/5695/890/8655/9738/4331/983/1026/6790/5714/4957/1871/9861/5566/5715/5519/5711/5928/5701/5688/5687/91750/23291/7846/113457/5685/7283/5683/5698/347733/5708/3320/5692/22919/5686/5713/80097/2033/995/10376/5699/5710/5702/10540/5520/7157/8900/5719/5577/5704/6233/3326/80254/5716/55957/7514/7311/54930/23194/5518/10133/10383/55835/5347/84790/9662/5694/1453/7465/5108/1022/8481/5693/5721/4660/5696/7280/132660/5691/5500/7314/5515/1778/5516 138 Vaccinia_virus R-HSA-72649 Translation initiation complex formation 57/3478 58/10654 5.623930150668437e-27 7.636414959486063e-26 3.093451775341875e-26 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6230/6222/8668/8667/6224/51065/8662/10480/26986/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/6192/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1974/1968 57 Vaccinia_virus R-HSA-72702 Ribosomal scanning and start codon recognition 57/3478 58/10654 5.623930150668437e-27 7.636414959486063e-26 3.093451775341875e-26 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6230/6222/1983/8668/8667/6224/51065/8662/10480/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/7458/6204/8663/6228/8894/6192/1981/6235/1973/6207/1977/6233/1975/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1974/1968 57 Vaccinia_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 72/3478 80/10654 8.186421840724049e-27 1.1007955581944473e-25 4.459236424226794e-26 3839/23165/3837/3838/5903/5335/55706/7175/9631/2316/4600/348995/9636/317649/79023/57122/23636/11274/8638/25820/1982/7706/10762/9470/23511/7316/2317/53371/4734/3434/6772/23279/4927/9688/79902/23586/8672/6041/3840/9883/4939/6059/1981/1973/3661/8086/7324/9246/1977/51191/4599/6233/23225/3716/7311/9972/7318/5610/5300/9775/8021/4940/6396/129401/7334/4938/55746/5495/1974/8480/7314/5595 72 Vaccinia_virus R-HSA-8943724 Regulation of PTEN gene transcription 59/3478 61/10654 1.2621274946329954e-26 1.6808140192949024e-25 6.808845694730634e-26 1912/3725/6591/8841/5468/1822/23186/2146/389541/5978/9112/9219/8535/51564/6045/5594/84232/80012/5931/58528/153129/1911/1108/57167/2122/7101/64223/10014/1958/5928/84733/10325/57459/8649/54815/23512/57332/6009/6615/3066/3065/7157/1107/23028/10542/2475/55004/57504/1386/10670/8726/648/23466/64121/53615/57521/6015/28956/5595 59 Vaccinia_virus R-HSA-2871837 FCERI mediated NF-kB activation 73/3478 82/10654 1.8181697665122521e-26 2.3982525015423514e-25 9.715132687228376e-26 8454/1147/5718/5689/5170/8945/5684/5720/4790/6885/5682/5700/122706/7321/5707/84433/5690/5717/9491/23198/6500/23118/10892/143471/5706/5705/10197/8517/7316/10213/5709/5695/7335/5970/4792/8915/5714/9861/7322/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/10454/5702/5719/7189/5704/6233/5716/7311/7334/5694/3551/5693/5721/5696/997/5691/7314/257397 73 Vaccinia_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 91/3478 112/10654 2.422414617210106e-26 3.165136080033959e-25 1.28217178845381e-25 5295/8454/1147/5718/5689/5777/8945/5684/4893/4773/5720/4790/6885/5579/5966/5682/4690/4772/5700/122706/5707/5336/84433/5690/5532/4775/5717/9491/23198/6500/930/10892/143471/5706/3708/5705/10197/8517/5530/7220/7316/10213/5709/5695/5970/4792/6850/4793/8915/5714/9861/5715/5711/5701/5688/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/2534/5534/5699/5710/5702/2280/695/5478/5719/6654/5704/6233/2885/5716/7409/7311/3845/5694/3265/3551/801/5693/5721/5696/5691/7314 91 Vaccinia_virus R-HSA-69275 G2/M Transition 136/3478 196/10654 2.6170543849216286e-26 3.3874956290807998e-25 1.372247896864956e-25 10844/8454/115106/5718/1017/5689/8945/22995/84617/5684/994/5720/4605/902/2305/5682/22981/7531/51512/10142/4659/5700/11190/122706/5707/203068/51807/7532/1454/22974/5690/10382/3161/5717/9491/23198/6500/7277/143471/5706/9133/10381/5705/10197/7278/286826/112714/5048/7316/10213/5709/9978/891/993/5695/890/8655/9738/4331/983/1026/6790/5714/4957/9861/5566/5715/5519/5711/5928/5701/5688/5687/91750/23291/7846/113457/5685/7283/5683/5698/347733/5708/3320/5692/22919/5686/5713/80097/2033/995/10376/5699/5710/5702/10540/5520/7157/8900/5719/5577/5704/6233/3326/80254/5716/55957/7514/7311/54930/23194/5518/10133/10383/55835/5347/84790/9662/5694/1453/7465/5108/1022/8481/5693/5721/4660/5696/7280/132660/5691/5500/7314/5515/1778/5516 136 Vaccinia_virus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 58/3478 60/10654 3.782493383095713e-26 4.806195720722534e-25 1.9469521711154176e-25 8454/1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/9039/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/9020/5970/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/4791/7314 58 Vaccinia_virus R-HSA-5610780 Degradation of GLI1 by the proteasome 58/3478 60/10654 3.782493383095713e-26 4.806195720722534e-25 1.9469521711154176e-25 8454/5718/5689/8945/5684/5720/2735/5682/5700/122706/5707/5567/5690/5568/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/8650/5714/9861/5566/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/83737/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 58 Vaccinia_virus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 55/3478 56/10654 5.207730124028327e-26 6.539549872055381e-25 2.649120335782267e-25 5718/3303/5689/5684/5720/5682/5700/122706/5707/5690/3184/5717/9491/3315/23198/26986/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/1981/5699/5710/5702/5719/5704/6233/5716/7311/5694/3304/3312/5693/5721/5696/5691/7314 55 Vaccinia_virus R-HSA-5683057 MAPK family signaling cascades 183/3478 294/10654 5.241083290961352e-26 6.539549872055381e-25 2.649120335782267e-25 5923/5718/2308/5689/27161/3725/1839/5684/2674/4893/6464/6711/685/5720/3667/71/2309/5682/1844/5604/2904/3561/5747/153090/5700/10642/3815/122706/5707/283455/5567/8844/10048/3674/7094/5690/57690/5594/2069/5568/5717/8074/9491/3315/23198/27327/409/5908/7414/10817/143471/5706/2064/5921/5705/10197/3337/192670/8550/8452/54518/5528/7316/10213/5709/673/9978/1950/3560/5695/1852/4233/983/5597/84078/3718/5714/22866/6714/5605/4609/9861/5566/5715/5037/5519/5711/10256/2261/5701/5688/5159/5687/3558/3717/2247/5685/2244/8649/5683/5698/5708/3084/145957/5692/5686/5713/2335/2534/3690/408/5699/1445/5710/2264/8555/5702/192669/998/2066/5894/8556/896/5719/23112/1742/6654/9542/5704/6233/5527/2885/10718/6709/3716/5716/88/2266/8660/7514/7311/8997/8826/5906/5518/2243/7450/1956/60/5536/4140/4343/3570/3845/5694/3265/3559/26523/5058/369/801/4763/7297/5781/8202/3569/5693/5924/5721/8682/5696/5691/5245/7529/5156/7314/3572/1846/5879/28956/5595/5515/5516 183 Vaccinia_virus R-HSA-166166 MyD88-independent TLR4 cascade 83/3478 99/10654 5.722008098112527e-26 7.013257713173319e-25 2.8410156649221953e-25 8454/23643/1147/3665/23098/3725/11035/8945/5601/351/4790/6885/5606/5604/7321/8737/10392/8767/29110/5594/6500/330/23118/841/7099/8517/5528/7323/7316/79155/7335/5970/4792/4793/3146/7322/5519/64127/5598/1432/329/466/23291/929/5602/3656/6195/10454/6288/3661/3654/7189/6285/5609/6233/10010/1385/2353/6196/7311/5518/1386/7187/8772/9641/6197/5599/353376/5600/7334/3551/6416/5781/5608/4791/51231/7314/1846/5595/5515/148022/257397/5516 83 Vaccinia_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 83/3478 99/10654 5.722008098112527e-26 7.013257713173319e-25 2.8410156649221953e-25 8454/23643/1147/3665/23098/3725/11035/8945/5601/351/4790/6885/5606/5604/7321/8737/10392/8767/29110/5594/6500/330/23118/841/7099/8517/5528/7323/7316/79155/7335/5970/4792/4793/3146/7322/5519/64127/5598/1432/329/466/23291/929/5602/3656/6195/10454/6288/3661/3654/7189/6285/5609/6233/10010/1385/2353/6196/7311/5518/1386/7187/8772/9641/6197/5599/353376/5600/7334/3551/6416/5781/5608/4791/51231/7314/1846/5595/5515/148022/257397/5516 83 Vaccinia_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 70/3478 78/10654 6.388128282589085e-26 7.761015501215687e-25 3.143926477026761e-25 1147/3443/3665/3441/351/7186/4790/80143/7321/8737/9140/29110/57506/79132/4214/9636/54476/3449/841/7706/8517/3444/84166/8887/7323/9474/7316/5970/4792/4793/3093/3146/23586/7322/7128/1387/3451/843/3448/2033/64135/3440/6288/54941/83737/3661/9246/7189/6285/51191/6233/10010/7311/55593/84282/7318/79671/5094/7187/8772/5300/3452/9641/1540/3551/3456/4791/3446/7314/3445 70 Vaccinia_virus R-HSA-5610787 Hedgehog 'off' state 91/3478 113/10654 8.493477185402828e-26 1.0229100784159058e-24 4.143728457500877e-25 8454/5718/5689/8945/84617/5684/5720/55081/2735/5682/5700/122706/5707/5567/11127/1452/5690/27152/10382/5568/5717/9491/23198/6500/112/7277/143471/114/5706/10381/5705/10197/108/7278/5573/113/7316/10213/5709/9978/5695/2778/5727/8650/111/107/5714/9861/5566/5715/5711/2932/5701/5688/5687/7846/5576/113457/5685/5683/5698/347733/5708/5692/5686/5713/10376/5699/5710/5702/83737/5719/5577/5704/6233/5716/7311/10383/23322/84790/196883/115/5694/8481/5693/5721/5696/7280/109/5691/7314 91 Vaccinia_virus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 57/3478 59/10654 1.132728467656589e-25 1.3524387307796344e-24 5.478623169337222e-25 8454/1147/5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/9039/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/9020/5714/9861/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/9040/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/4791/7314 57 Vaccinia_virus R-HSA-8941858 Regulation of RUNX3 expression and activity 54/3478 55/10654 1.5835145076147635e-25 1.874502216279015e-24 7.59346138154448e-25 57154/5718/5689/5684/5720/5682/1029/864/5700/5707/5690/5717/9491/5706/5705/10197/64750/7316/10213/5709/865/5695/5714/6714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/2033/5699/5710/5702/5719/5704/6233/5716/7311/7040/5694/5693/5721/5696/5691/7314/4193 54 Vaccinia_virus R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 90/3478 112/10654 2.1312952277743484e-25 2.5015626190402308e-24 1.0133633866224155e-24 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6147/6159/6129/6217/6230/6222/1650/6176/6152/6136/6125/6224/6146/6154/51065/6141/6184/6202/6123/6232/6134/6169/6160/6164/6155/6748/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/6192/140801/6156/6235/6143/6181/6124/6185/6207/6139/6745/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133 90 Vaccinia_virus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 53/3478 54/10654 4.81247718216592e-25 5.554400747749832e-24 2.2500441562231888e-024 8454/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/6790/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/23194/5694/5693/5721/5696/5691/7314 53 Vaccinia_virus R-HSA-9604323 Negative regulation of NOTCH4 signaling 53/3478 54/10654 4.81247718216592e-25 5.554400747749832e-24 2.2500441562231888e-024 8454/5718/5689/5684/5720/5682/5700/5707/207/5690/5717/9491/6500/5706/5705/10197/10460/7534/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/4855/55294/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 53 Vaccinia_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 79/3478 94/10654 6.4590175014854525e-25 7.39317292525401e-24 2.9949163360519752e-24 8454/1147/3665/23098/3725/11035/8945/5601/351/4790/6885/5606/5604/7321/8737/10392/8767/29110/5594/6500/330/23118/841/8517/7098/5528/7323/7316/79155/7335/5970/4792/4793/3146/7322/5519/64127/5598/1432/329/466/23291/5602/3656/6195/10454/6288/3661/3654/7189/6285/5609/6233/10010/1385/2353/6196/7311/5518/1386/7187/8772/9641/6197/5599/5600/7334/3551/6416/5608/4791/51231/7314/1846/5595/5515/148022/257397/5516 79 Vaccinia_virus R-HSA-69541 Stabilization of p53 55/3478 57/10654 1.0134582469749323e-24 1.1505243213608864e-23 4.660683741480923e-24 5718/5689/5684/5720/5682/1029/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/472/5705/10197/7316/10213/5709/5695/5714/9861/4194/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/51230/5693/5721/5696/5691/7314/4193 55 Vaccinia_virus R-HSA-5610783 Degradation of GLI2 by the proteasome 57/3478 60/10654 1.5467831925250455e-24 1.727657033586442e-23 6.998603069744053e-24 8454/5718/5689/8945/5684/5720/5682/5700/122706/5707/5567/1452/5690/5568/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5566/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 57 Vaccinia_virus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 57/3478 60/10654 1.5467831925250455e-24 1.727657033586442e-23 6.998603069744053e-24 8454/5718/5689/8945/5684/5720/5682/5700/122706/5707/5567/1452/5690/5568/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5566/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 57 Vaccinia_virus R-HSA-1169408 ISG15 antiviral mechanism 65/3478 72/10654 1.6944834071264364e-24 1.8774876150960915e-23 7.605554997881184e-24 3839/23165/3837/3838/5903/5335/55706/7175/9631/4600/348995/9636/317649/79023/57122/23636/11274/25820/1982/7706/10762/9470/23511/7316/2317/53371/4734/3434/6772/23279/4927/9688/79902/23586/8672/3840/9883/1981/1973/3661/8086/7324/9246/1977/51191/4599/6233/23225/3716/7311/9972/7318/5610/5300/9775/8021/6396/129401/7334/55746/5495/1974/8480/7314/5595 65 Vaccinia_virus R-HSA-5621481 C-type lectin receptors (CLRs) 105/3478 142/10654 4.13821077626108e-24 4.5487475596203143e-23 1.8426619413092362e-23 8454/1147/5718/5689/5170/8945/5684/4893/4773/5720/4790/6885/5682/4772/5700/122706/7321/5707/5567/5336/84433/5690/3553/5532/9039/5568/4775/4582/5717/9491/23198/6500/23118/10892/29108/143471/5706/3708/5705/841/10197/8517/5530/7316/10213/5709/5695/9020/7335/5970/4792/6850/8915/5714/6714/9861/5566/7322/5715/5711/5701/5688/1387/5687/4067/23291/5685/5683/5698/5708/5692/5686/5713/2534/2033/5534/5699/5710/10454/5702/9040/5894/5719/7189/5704/6233/5580/30835/5716/7311/3845/7334/5694/3265/3551/5058/801/5693/5721/5696/997/5691/4791/7314/257397 105 Vaccinia_virus R-HSA-180534 Vpu mediated degradation of CD4 51/3478 52/10654 4.437721708668195e-24 4.691789745424008e-23 1.900607208292606e-23 5718/5689/8945/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/920/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Vaccinia_virus R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 51/3478 52/10654 4.437721708668195e-24 4.691789745424008e-23 1.900607208292606e-23 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Vaccinia_virus R-HSA-69610 p53-Independent DNA Damage Response 51/3478 52/10654 4.437721708668195e-24 4.691789745424008e-23 1.900607208292606e-23 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Vaccinia_virus R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 51/3478 52/10654 4.437721708668195e-24 4.691789745424008e-23 1.900607208292606e-23 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/11200/143471/5706/5705/10197/7316/10213/5709/993/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/1111/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Vaccinia_virus R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 51/3478 52/10654 4.437721708668195e-24 4.691789745424008e-23 1.900607208292606e-23 5718/5689/1019/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/595/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 51 Vaccinia_virus R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 53/3478 55/10654 9.037998805777084e-24 9.483051777273684e-23 3.8415098592338e-23 8454/5718/5689/8945/5684/5720/5682/5700/122706/5707/991/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/51343/7311/5694/5693/5721/5696/5691/7314 53 Vaccinia_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 65/3478 73/10654 1.0554629539460833e-23 1.0991099182070115e-22 4.45240802891383e-23 8454/57154/5718/5689/7291/5684/5720/5682/5700/122706/5707/10273/5690/5717/9491/23198/6500/143471/5706/5705/10197/7316/10213/5709/9978/865/5695/11059/5714/6772/2099/9861/5715/5711/2932/5701/5688/5687/6502/650/2908/5685/5683/5698/5708/5692/5686/5713/55294/5699/5710/5702/5719/5704/6233/5716/7311/860/5694/5693/5721/5696/5691/10891/7314 65 Vaccinia_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 47/3478 47/10654 1.142705123505802e-23 1.181079549295176e-22 4.784460572102062e-23 8454/8841/7090/79718/79885/2648/9734/892/55869/23462/51564/55534/3280/6500/84441/3091/10013/10046/7316/83933/9978/9611/7091/9759/9612/1024/4609/10014/22938/8850/1387/6907/26508/2033/55294/3066/3065/7088/9794/6233/23493/7311/7089/388585/3516/4851/7314 47 Vaccinia_virus R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 50/3478 51/10654 1.346460161027534e-23 1.3813683874245442e-22 5.595814938227491e-23 8669/6203/6227/6206/6194/1965/6234/27335/6191/8666/6217/6230/6222/8668/8667/6224/51065/8662/10480/6202/6232/8661/6218/6209/1964/6193/6210/6231/6229/6205/6204/8663/6228/8894/6192/6235/6207/6233/6223/8664/3646/51386/3921/6188/6189/8665/6201/6187/6208/1968 50 Vaccinia_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 74/3478 88/10654 1.9022256599622028e-23 1.9371930434173902e-22 7.847417002785248e-23 5718/3303/5689/5684/5720/5682/5073/5700/122706/5707/3842/207/5690/5578/3184/5717/9491/3315/23198/26986/143471/5706/5705/10197/7534/7316/10213/5709/5695/5714/9861/5715/5711/1432/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/1981/5699/5710/5702/5719/5704/6233/5580/5716/7514/7311/11340/8021/54464/5600/5694/3304/3312/8570/6418/23016/5693/54512/5721/5696/5691/167227/7529/7314/1994 74 Vaccinia_virus R-HSA-1234174 Cellular response to hypoxia 66/3478 75/10654 2.1693423219160164e-23 2.1930942451486736e-22 8.884052689828942e-23 5718/5689/5684/5720/5682/112399/5700/122706/7321/5707/7422/5690/5717/9491/23198/3091/143471/5706/5705/10197/7323/7316/10213/5709/9978/5695/5714/8994/9861/7322/5715/5711/10370/5701/5688/1387/5687/112398/5685/5683/5698/5708/5692/5686/5713/2033/5699/5710/7428/5702/8453/5719/5704/6233/2056/5716/7311/55662/5694/405/5693/5721/5696/5691/768/7314 66 Vaccinia_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 78/3478 95/10654 2.582016317644469e-23 2.572728489163733e-22 1.0421921221541098e-22 8454/23643/1147/3725/8945/5601/351/4790/6885/5606/5604/11213/10392/8767/5594/4214/6500/23118/246330/10333/7099/8517/4615/5528/7316/79155/7335/5970/4792/7096/59307/4793/8651/3146/5519/64127/5598/1432/466/23291/929/5602/114609/3656/6195/57162/10454/6288/695/3654/7189/6285/5609/6233/51135/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/7097/3551/6416/5608/57161/4791/51231/7314/1846/5595/5515/257397/5516 78 Vaccinia_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 78/3478 95/10654 2.582016317644469e-23 2.572728489163733e-22 1.0421921221541098e-22 8454/23643/1147/3725/8945/5601/351/4790/6885/5606/5604/11213/10392/8767/5594/4214/6500/23118/246330/10333/7099/8517/4615/5528/7316/79155/7335/5970/4792/7096/59307/4793/8651/3146/5519/64127/5598/1432/466/23291/929/5602/114609/3656/6195/57162/10454/6288/695/3654/7189/6285/5609/6233/51135/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/7097/3551/6416/5608/57161/4791/51231/7314/1846/5595/5515/257397/5516 78 Vaccinia_virus R-HSA-162909 Host Interactions of HIV factors 97/3478 129/10654 2.721508735663855e-23 2.692349713496028e-22 1.090649741435214e-22 5718/23165/5689/5905/8945/1173/3837/5684/5903/8065/5720/55706/7175/162/5682/9631/3159/5700/122706/5707/5690/5717/4869/9491/23198/6500/348995/143471/79023/5706/5705/57122/23636/10197/10762/23511/7316/10213/5709/9978/5695/53371/920/292/5714/23279/4927/9688/9861/79902/5715/5711/9883/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/2534/5699/5710/5702/5901/8086/5478/5719/5704/6233/23225/5716/7514/1025/9844/7311/9972/3932/8021/6396/129401/375/904/5694/1104/55746/5693/5721/5696/5691/8480/291/7314/5879 97 Vaccinia_virus R-HSA-8948751 Regulation of PTEN stability and activity 62/3478 69/10654 3.703920874843403e-23 3.6382485189064633e-22 1.4738259248163746e-22 5718/5689/5684/5720/5682/1459/5700/122706/5707/10273/207/5690/5717/9491/23198/1460/143471/5706/5705/10197/7316/10213/5709/5695/1457/4734/5714/11060/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/10000/5692/5686/5713/5728/5699/2444/5710/5702/5719/5987/208/5704/6233/5716/7311/331/5694/5693/5721/5696/23608/5691/7314 62 Vaccinia_virus R-HSA-4641258 Degradation of DVL 54/3478 57/10654 3.928506782329137e-23 3.8316773898069406e-22 1.5521824425362714e-22 5718/5689/5684/5720/5682/5700/122706/5707/1856/5690/5717/9491/23198/143471/5706/5705/10197/8452/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/1855/5716/1857/23072/7311/5694/5693/5721/5696/5691/7314 54 Vaccinia_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 70/3478 82/10654 4.8991918199211775e-23 4.745021447965616e-22 1.9221709532705098e-22 8454/5718/5689/51176/8945/5684/5720/7090/1487/5682/1499/5700/122706/5707/1452/5690/5717/9491/23198/6500/143471/5706/5705/10197/5528/7316/10213/5709/9978/5695/7091/5714/9861/5715/5519/5711/2932/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/324/5699/8312/5710/5702/3065/7088/5719/5704/6233/5527/5716/7311/5518/7089/5694/5693/5721/5696/5691/7314/5515/5516 70 Vaccinia_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 124/3478 182/10654 5.596705120885255e-23 5.382942078073666e-22 2.180587594613919e-22 1912/23165/7020/7150/5905/5893/6670/5903/7068/55706/7175/1487/5241/3622/9631/5468/7021/1029/7486/1788/9112/8535/51564/1786/6045/9212/51588/4869/3090/80012/7153/348995/79023/6613/57122/23636/8517/332/3183/10762/5465/5885/23511/10210/28996/53371/1655/5970/4792/3190/6996/9759/9612/8856/1911/9994/6790/641/6672/5111/2099/23279/4927/9688/79902/9656/9883/7341/1387/84733/10521/1616/2908/2033/23512/165918/8243/9126/57332/7022/142/9971/7428/3066/3065/7157/1107/6256/8086/7329/5987/5371/8924/23225/672/115426/7158/10155/367/9972/10499/6612/9063/7155/25942/8021/9641/6117/6294/6396/648/129401/11315/55746/8648/7421/4286/4791/8480/10891/7508/6015/4193/8554 124 Vaccinia_virus R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 53/3478 56/10654 1.1521899942277745e-22 1.1005400979348053e-21 4.458201574761552e-22 5718/5689/5684/5720/5682/5700/122706/5707/10956/5690/5717/9491/23198/143471/5706/5705/10197/84447/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/6400/5710/5702/5719/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 53 Vaccinia_virus R-HSA-5689880 Ub-specific processing proteases 142/3478 220/10654 1.3047221565443797e-22 1.2376987580917575e-21 5.013820543894407e-22 9960/5718/23358/5689/5684/8295/5720/7186/645836/6885/5682/2648/79594/5700/10474/122706/5707/991/8737/8237/7375/5690/55611/2625/9817/4303/100287364/5717/9491/57646/23198/63967/409/6478/4086/1080/330/3091/143471/5706/100287513/5705/57695/11274/27005/10197/8517/64750/7416/8239/7316/10213/5709/993/5695/29761/890/7417/25862/4792/9738/9986/84132/5714/4092/8678/9100/1643/79589/4609/392188/9861/55288/4194/23586/4089/5715/100287144/100287441/5711/5701/5688/9097/329/5687/7046/6502/9099/4088/5685/5683/5698/5708/9146/5692/5686/5713/100287478/408/64135/5728/5699/8724/8312/5710/10454/100287327/5702/219333/7157/8900/9958/4087/63891/5719/7189/57599/5704/6233/377630/5716/7311/367/6881/51616/23770/728386/1540/5694/7874/100287404/5693/154/10254/5721/100287178/5696/5691/100287205/7314/4193/100287238 142 Vaccinia_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 76/3478 93/10654 1.6788487419210243e-22 1.5710848024058236e-21 6.364341247822944e-22 54106/8454/23643/1147/3665/3725/8945/5601/351/4790/6885/5606/5604/10392/8767/5594/4214/6500/23118/246330/7099/8517/4615/5528/7316/79155/7335/5970/4792/4793/3146/5519/64127/5598/1432/466/23291/929/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/51311/51135/1385/2353/6196/7311/5518/1386/6197/5599/353376/5600/7334/3551/6416/5608/57161/4791/51231/51284/7314/1846/5595/5515/148022/257397/5516 76 Vaccinia_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 76/3478 93/10654 1.6788487419210243e-22 1.5710848024058236e-21 6.364341247822944e-22 54106/8454/23643/1147/3665/3725/8945/5601/351/4790/6885/5606/5604/10392/8767/5594/4214/6500/23118/246330/7099/8517/4615/5528/7316/79155/7335/5970/4792/4793/3146/5519/64127/5598/1432/466/23291/929/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/51311/51135/1385/2353/6196/7311/5518/1386/6197/5599/353376/5600/7334/3551/6416/5608/57161/4791/51231/51284/7314/1846/5595/5515/148022/257397/5516 76 Vaccinia_virus R-HSA-2408522 Selenoamino acid metabolism 90/3478 118/10654 1.8854418055693095e-22 1.7525751011499957e-21 7.099544206064585e-22 6158/6138/6144/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/6147/6159/6129/6217/191/6230/6222/6176/6152/6136/6125/6224/6146/6154/51065/6141/6202/6123/875/6232/6134/6169/6160/6164/6155/6175/6218/6209/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/9061/6204/6228/23521/116832/7965/6192/140801/6156/6235/6143/6181/6124/6207/6139/6233/7311/6223/25873/3921/6188/6189/6135/6201/6161/9045/6187/6168/6208/6157/6137/6170/200916/6122/6133/7296 90 Vaccinia_virus R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/3478 52/10654 2.391365991504524e-22 2.2037619257582077e-21 8.927266626860153e-22 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/472/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/7157/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Vaccinia_virus R-HSA-2990846 SUMOylation 126/3478 188/10654 2.402657406422306e-22 2.2037619257582077e-21 8.927266626860153e-22 1912/10054/23165/7020/7150/5905/5893/6670/5903/7068/29843/55706/7175/1487/5241/3622/9631/5468/7021/1029/7486/1788/9112/8535/51564/1786/6045/9212/51588/4869/3090/80012/7153/348995/79023/6613/57122/23636/8517/332/3183/10762/5465/5885/23511/10210/28996/53371/1655/5970/4792/3190/6996/9759/9612/8856/1911/9994/6790/641/6672/5111/2099/23279/4927/9688/79902/9656/9883/7341/1387/84733/10521/1616/2908/2033/23512/165918/8243/9126/57332/7022/142/9971/7428/3066/3065/7157/1107/6256/8086/7329/5987/5371/8924/23225/672/115426/7158/10155/367/9972/10499/6612/9063/7155/25942/8021/9641/6117/6294/6396/648/129401/11315/55746/8648/7421/4286/4791/8480/10891/7508/6015/4193/8554 126 Vaccinia_virus R-HSA-6802952 Signaling by BRAF and RAF fusions 60/3478 67/10654 2.8701785723827405e-22 2.6152613965461153e-21 1.0594218691689754e-21 4000/27044/8805/22906/4893/71/8087/5604/10018/10142/55750/283455/8844/3674/7094/5594/409/5908/7414/10533/55109/23164/54845/54518/673/8546/57085/22866/6714/5605/5037/9061/80853/10256/3717/10827/2244/2335/3690/408/1445/5894/2266/56829/8826/5906/2243/7450/60/1185/4140/9444/3845/3265/369/801/9715/7529/57670/5595 60 Vaccinia_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 78/3478 97/10654 3.2750527635231887e-22 2.9646719460651086e-21 1.2009653408722805e-21 54106/8454/23643/1147/3665/3725/8945/5601/351/4790/6885/5606/5604/10392/8767/5594/4214/6500/8411/23118/246330/7099/8517/4615/5528/7316/79155/7335/5970/4792/5289/4793/3146/5519/64127/5598/1432/466/23291/929/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/51311/51135/1385/2353/6196/7311/5518/1386/6197/5599/353376/5600/7334/3551/6416/5608/57161/4791/51231/51284/7314/1846/5595/5515/148022/257397/5516 78 Vaccinia_virus R-HSA-8948216 Collagen chain trimerization 44/3478 44/10654 3.372377208568568e-22 3.032949632381472e-21 1.2286240958079608e-21 255631/1310/1286/1287/1282/1308/1294/85301/169044/7373/1299/91522/256076/1284/136227/1305/1277/1280/1289/1307/1300/1298/1301/84570/1281/1297/1290/1303/1295/1288/1306/1292/81578/50509/1293/57642/340267/1285/131873/80781/1278/1296/1302/1291 44 Vaccinia_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 75/3478 92/10654 4.264797705048235e-22 3.810803110639874e-21 1.5437264358510758e-21 54106/8454/23643/1147/3725/8945/5601/351/4790/6885/5606/5604/10392/8767/5594/4214/6500/23118/246330/7099/8517/4615/5528/7316/79155/7335/5970/4792/4793/3146/5519/64127/5598/1432/466/23291/929/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/51311/51135/1385/2353/6196/7311/5518/1386/6197/5599/353376/5600/7334/3551/6416/5608/57161/4791/51231/51284/7314/1846/5595/5515/148022/257397/5516 75 Vaccinia_virus R-HSA-162587 HIV Life Cycle 107/3478 152/10654 9.891032978128247e-22 8.781461970966423e-21 3.557301334239106e-21 6884/23165/6875/5905/2963/2237/5434/5440/5903/7852/902/55706/7175/9631/3159/5430/6874/5436/5045/7520/6878/404672/6749/348995/79023/5441/57122/23636/5438/3978/3981/10762/5431/23511/5435/4686/7316/6872/53371/920/4331/5433/4836/9397/23279/4927/9688/8148/2966/8731/79902/6879/9150/2962/23327/9883/54457/5437/8812/29082/83860/8732/2965/128866/905/2068/5439/2071/5901/8086/5478/6873/6827/6233/23225/2968/7514/1025/7311/9972/6881/2967/51616/6880/6908/8021/7251/11198/6396/129401/904/6883/6829/1104/51497/2547/6882/138474/1022/5432/55746/22916/1234/8178/8480/6877/7314 107 Vaccinia_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 78/3478 98/10654 1.0953061050549173e-21 9.540873933968934e-21 3.864933161166971e-21 8454/23643/1147/3725/8945/5601/351/4790/6885/5606/5604/11213/10392/8767/5594/4214/6500/23118/246330/10333/7099/8517/4615/5528/7316/79155/7335/5970/4792/7096/59307/4793/8651/3146/5519/64127/5598/1432/466/23291/929/5602/114609/3656/6195/57162/10454/6288/695/3654/7189/6285/5609/6233/51135/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/7097/3551/6416/5608/57161/4791/51231/7314/1846/5595/5515/257397/5516 78 Vaccinia_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 78/3478 98/10654 1.0953061050549173e-21 9.540873933968934e-21 3.864933161166971e-21 8454/23643/1147/3725/8945/5601/351/4790/6885/5606/5604/11213/10392/8767/5594/4214/6500/23118/246330/10333/7099/8517/4615/5528/7316/79155/7335/5970/4792/7096/59307/4793/8651/3146/5519/64127/5598/1432/466/23291/929/5602/114609/3656/6195/57162/10454/6288/695/3654/7189/6285/5609/6233/51135/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/7097/3551/6416/5608/57161/4791/51231/7314/1846/5595/5515/257397/5516 78 Vaccinia_virus R-HSA-202424 Downstream TCR signaling 78/3478 98/10654 1.0953061050549173e-21 9.540873933968934e-21 3.864933161166971e-21 5295/8454/1147/5718/5689/5170/8945/5684/5290/5720/4790/6885/5682/5291/5700/122706/7321/5707/8767/84433/5690/5717/9491/23198/6500/23118/10892/143471/5706/5705/10197/8517/7316/10213/5709/5695/920/7335/5970/4792/8915/5714/9861/7322/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/5692/5686/5713/5728/5699/5710/5702/5719/7189/5704/6233/5716/7311/3932/5296/7334/5694/3551/5693/5721/5696/997/5691/7314 78 Vaccinia_virus R-HSA-6802957 Oncogenic MAPK signaling 62/3478 71/10654 1.191587598906277e-21 1.031468015303246e-20 4.178395988270037e-21 4000/27044/8805/22906/4893/71/8087/5604/10018/10142/55750/283455/8844/3674/7094/5594/409/5908/7414/10533/55109/23164/54845/54518/673/8546/57085/22866/6714/5605/5037/9061/80853/10256/3717/10827/2244/2335/3690/408/1445/5894/2266/56829/8826/5906/2243/7450/60/1185/4140/9444/3845/3265/369/801/9715/4763/5245/7529/57670/5595 62 Vaccinia_virus R-HSA-5358351 Signaling by Hedgehog 105/3478 149/10654 2.0932315462845667e-21 1.8006991873317545e-20 7.294491102776556e-21 8454/57154/5718/5689/8945/84617/5684/5720/55081/2735/5682/5700/122706/5707/5567/10956/11127/22873/1452/5690/27152/10382/5568/5717/9491/23198/6500/409/112/7277/143471/114/5706/10381/5705/10197/108/7278/64750/5573/113/8452/84447/7316/10213/5709/9978/5695/2778/5727/8650/111/107/5714/7415/9861/5566/5715/5711/2932/5701/5688/5687/7846/5576/113457/5685/5683/5698/347733/5708/5692/5686/5713/408/10376/5699/6400/5710/5702/83737/5719/6868/5577/5704/6233/5716/7311/147111/10383/6469/23322/84790/196883/115/5694/8481/5693/5721/5696/7280/109/5691/5034/7314 105 Vaccinia_virus R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 48/3478 50/10654 2.113548924442819e-21 1.80695386441562e-20 7.319828308824059e-21 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 48 Vaccinia_virus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 47/3478 49/10654 6.274114195769348e-21 5.3310724914972684e-20 2.1595756321246773e-20 1017/9134/1820/57060/7027/25946/7832/4849/1027/4869/898/4850/2810/9337/5934/1869/891/890/10769/983/1026/6790/5933/5111/25904/246175/1647/4848/23019/28984/2033/995/1874/7157/8900/10498/55571/55835/5325/581/57472/3276/144455/85456/79733/29883/1263 47 Vaccinia_virus R-HSA-913531 Interferon Signaling 129/3478 199/10654 6.801650247875746e-21 5.74407658128531e-20 2.326880347957492e-20 80263/3839/3443/23165/3665/3460/5777/3837/3838/3441/5903/6737/10379/5335/55706/7175/960/5770/9631/23321/7412/2316/2633/9021/85363/54739/9830/4600/348995/9636/317649/79023/2537/3383/57122/23636/11274/8638/3449/25820/1982/7706/3444/10762/9470/23511/7316/2317/53371/3663/8519/4734/3434/6672/6772/8651/23279/4927/9688/3659/3433/79902/23586/8672/6041/3840/3459/1958/25939/9883/4939/7341/6059/3451/3717/3448/1981/3440/1973/10612/3458/3454/3661/8086/7324/10346/9246/1977/5371/51191/4599/6233/23225/5580/3716/7311/81603/9972/10107/7318/5610/10581/5300/9775/8021/3452/4940/91543/6396/3437/129401/7334/7726/3456/6773/4938/7297/5781/3430/55746/5696/5495/1974/3446/8480/7314/3445/5595/8554 129 Vaccinia_virus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 58/3478 66/10654 1.2434952367371578e-20 1.0437823653824022e-19 4.228280454104658e-20 5718/5689/5684/5720/5682/112399/5700/122706/7321/5707/5690/5717/9491/23198/3091/143471/5706/5705/10197/7323/7316/10213/5709/9978/5695/5714/8994/9861/7322/5715/5711/5701/5688/5687/112398/5685/5683/5698/5708/5692/5686/5713/5699/5710/7428/5702/8453/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 58 Vaccinia_virus R-HSA-9607240 FLT3 Signaling 160/3478 267/10654 1.910422067218141e-20 1.5939364837934489e-19 6.45691161589898e-20 5295/54106/5923/5718/5689/5170/1839/5684/2674/4893/6464/6711/685/5290/5720/3667/71/5682/1844/5291/5604/2904/3561/5747/153090/5700/3815/122706/5707/283455/8844/10048/3674/7094/5690/5594/2069/5717/8074/9491/23198/409/5908/7414/10817/143471/5706/2064/5921/5705/10197/8452/54518/6776/5528/7316/10213/5709/673/9978/1950/3560/5695/1852/5289/4233/84078/3718/5714/22866/6714/5605/9861/5715/5037/5519/5711/10256/2261/5701/5688/5159/5687/3558/3717/2247/5685/2244/8649/5683/5698/5708/3084/145957/5692/5686/5713/2335/2534/3690/408/5699/1445/5710/2264/5702/2066/5894/5719/208/1742/6654/9542/5704/6233/5527/2885/10718/6709/3716/5716/88/2266/8660/7311/8826/5906/9846/5518/2243/7450/1956/60/5536/5296/4140/3845/6777/5694/3265/3559/369/801/4763/5781/5693/5924/5721/8682/5696/5691/5245/7529/5156/7314/1846/28956/5595/5515/5516 160 Vaccinia_virus R-HSA-202403 TCR signaling 88/3478 119/10654 2.0557908805456448e-20 1.7049523170992325e-19 6.906628044946919e-20 5295/8454/1147/5718/5689/5170/8945/55740/5684/5290/5720/5335/4790/6885/5682/5291/4690/5700/122706/7321/5707/3937/8767/84433/5690/5717/9491/23198/6500/23118/10892/143471/5706/5705/10197/8517/7316/10213/5709/5695/920/7335/5970/4792/8915/5714/9861/7322/5715/5711/5701/5688/5687/23291/5685/5683/5698/5708/51466/5692/5686/5713/7408/5728/5699/1445/5710/5702/5719/7189/5704/6233/7454/5716/3702/7311/3932/5296/7334/5694/3551/5058/5693/5721/5696/997/5691/7314 88 Vaccinia_virus R-HSA-68882 Mitotic Anaphase 129/3478 201/10654 2.494882829404904e-20 2.0567932849558286e-19 8.331908195944949e-20 4000/5718/5689/5905/11130/84617/5684/5903/5720/11065/5682/246184/55869/1783/1058/5700/122706/7321/5707/991/51807/8697/5690/10382/9212/5717/9491/23198/23244/7277/348995/143471/55920/79023/5706/10381/5705/57122/79980/10197/7278/6232/332/7443/112714/1780/8881/23141/5885/5528/5048/7316/10213/5709/5695/5501/8655/4085/5714/23279/51433/9861/79902/3796/5715/5519/5711/5701/5688/699/5687/7846/113457/5685/5683/7444/5698/347733/5708/5692/22919/5686/5713/119504/8243/9126/10376/5699/5710/51143/5702/5520/51529/7324/5719/64682/29945/10393/9232/5704/6233/5527/9700/51434/5716/701/7514/7311/5518/25906/10383/5347/84790/29882/6396/5694/55746/7112/5693/5721/140735/5696/7280/5691/7314/996/5515/1778/5516 129 Vaccinia_virus R-HSA-180585 Vif-mediated degradation of APOBEC3G 50/3478 54/10654 2.661630993458967e-20 2.18127747097081e-19 8.836183864924506e-20 5718/5689/5684/8065/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/9978/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Vaccinia_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 69/3478 85/10654 3.1366483787725573e-020 2.525731398023251e-19 1.0231539693303384e-19 8454/1147/3725/8945/5601/351/81793/4790/6885/5606/5604/10392/8767/5594/4214/6500/23118/246330/8517/4615/7100/5528/7316/79155/7335/5970/4792/4793/3146/5519/64127/5598/1432/466/23291/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/51135/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/6416/5608/57161/4791/51231/7314/1846/5595/5515/257397/5516 69 Vaccinia_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 69/3478 85/10654 3.1366483787725573e-020 2.525731398023251e-19 1.0231539693303384e-19 8454/1147/3725/8945/5601/351/81793/4790/6885/5606/5604/10392/8767/5594/4214/6500/23118/246330/8517/4615/7100/5528/7316/79155/7335/5970/4792/4793/3146/5519/64127/5598/1432/466/23291/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/51135/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/6416/5608/57161/4791/51231/7314/1846/5595/5515/257397/5516 69 Vaccinia_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 69/3478 85/10654 3.1366483787725573e-020 2.525731398023251e-19 1.0231539693303384e-19 8454/1147/3725/8945/5601/351/81793/4790/6885/5606/5604/10392/8767/5594/4214/6500/23118/246330/8517/4615/7100/5528/7316/79155/7335/5970/4792/4793/3146/5519/64127/5598/1432/466/23291/5602/3656/6195/57162/10454/6288/3654/7189/6285/5609/6233/51135/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/6416/5608/57161/4791/51231/7314/1846/5595/5515/257397/5516 69 Vaccinia_virus R-HSA-5684996 MAPK1/MAPK3 signaling 154/3478 255/10654 3.4822916814192536e-20 2.7878462305003855e-19 1.1293346310900286e-19 5923/5718/5689/1839/5684/2674/4893/6464/6711/685/5720/3667/71/5682/1844/5604/2904/3561/5747/153090/5700/3815/122706/5707/283455/8844/10048/3674/7094/5690/5594/2069/5717/8074/9491/23198/409/5908/7414/10817/143471/5706/2064/5921/5705/10197/8452/54518/5528/7316/10213/5709/673/9978/1950/3560/5695/1852/4233/983/84078/3718/5714/22866/6714/5605/9861/5715/5037/5519/5711/10256/2261/5701/5688/5159/5687/3558/3717/2247/5685/2244/8649/5683/5698/5708/3084/145957/5692/5686/5713/2335/2534/3690/408/5699/1445/5710/2264/5702/2066/5894/5719/1742/6654/9542/5704/6233/5527/2885/10718/6709/3716/5716/88/2266/8660/7311/8826/5906/5518/2243/7450/1956/60/5536/4140/3570/3845/5694/3265/3559/369/801/4763/7297/5781/3569/5693/5924/5721/8682/5696/5691/5245/7529/5156/7314/3572/1846/28956/5595/5515/5516 154 Vaccinia_virus R-HSA-162599 Late Phase of HIV Life Cycle 98/3478 139/10654 4.356905300772887e-20 3.467996460672672e-19 1.4048581520338468e-19 6884/23165/6875/5905/2963/5434/5440/5903/902/55706/7175/9631/5430/6874/5436/5045/6878/404672/6749/348995/79023/5441/57122/23636/5438/10762/5431/23511/5435/4686/7316/6872/53371/4331/5433/4836/9397/23279/4927/9688/8148/2966/8731/79902/6879/9150/2962/23327/9883/54457/5437/8812/29082/83860/8732/2965/128866/905/2068/5439/2071/5901/8086/5478/6873/6827/6233/23225/2968/7514/1025/7311/9972/6881/2967/51616/6880/6908/8021/7251/11198/6396/129401/904/6883/6829/1104/51497/6882/138474/1022/5432/55746/22916/8178/8480/6877/7314 98 Vaccinia_virus R-HSA-2555396 Mitotic Metaphase and Anaphase 129/3478 202/10654 4.714822488891714e-20 3.731445226922871e-19 1.5115791798973134e-19 4000/5718/5689/5905/11130/84617/5684/5903/5720/11065/5682/246184/55869/1783/1058/5700/122706/7321/5707/991/51807/8697/5690/10382/9212/5717/9491/23198/23244/7277/348995/143471/55920/79023/5706/10381/5705/57122/79980/10197/7278/6232/332/7443/112714/1780/8881/23141/5885/5528/5048/7316/10213/5709/5695/5501/8655/4085/5714/23279/51433/9861/79902/3796/5715/5519/5711/5701/5688/699/5687/7846/113457/5685/5683/7444/5698/347733/5708/5692/22919/5686/5713/119504/8243/9126/10376/5699/5710/51143/5702/5520/51529/7324/5719/64682/29945/10393/9232/5704/6233/5527/9700/51434/5716/701/7514/7311/5518/25906/10383/5347/84790/29882/6396/5694/55746/7112/5693/5721/140735/5696/7280/5691/7314/996/5515/1778/5516 129 Vaccinia_virus R-HSA-5387390 Hh mutants abrogate ligand secretion 53/3478 59/10654 5.966824837520931e-20 4.695484318162778e-19 1.9021038507168998e-19 5718/5689/5684/5720/5682/5700/122706/5707/10956/5690/5717/9491/23198/143471/5706/5705/10197/84447/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/6400/5710/5702/5719/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 53 Vaccinia_virus R-HSA-2467813 Separation of Sister Chromatids 123/3478 190/10654 6.612861809457629e-20 5.174470963897636e-19 2.0961375821831197e-19 5718/5689/5905/11130/84617/5684/5903/5720/11065/5682/246184/55869/1783/1058/5700/122706/7321/5707/991/51807/8697/5690/10382/9212/5717/9491/23198/23244/7277/348995/143471/55920/79023/5706/10381/5705/57122/79980/10197/7278/6232/332/112714/1780/8881/5885/5528/5048/7316/10213/5709/5695/5501/8655/4085/5714/23279/51433/9861/79902/3796/5715/5519/5711/5701/5688/699/5687/7846/113457/5685/5683/5698/347733/5708/5692/22919/5686/5713/119504/8243/9126/10376/5699/5710/51143/5702/51529/7324/5719/64682/29945/10393/9232/5704/6233/5527/9700/51434/5716/701/7514/7311/5518/25906/10383/5347/84790/29882/6396/5694/55746/5693/5721/140735/5696/7280/5691/7314/996/5515/1778/5516 123 Vaccinia_virus R-HSA-169911 Regulation of Apoptosis 49/3478 53/10654 7.624993604313215e-20 5.932930416839215e-19 2.403383554759872e-19 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/7316/10213/5709/5695/5714/9861/5715/79658/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 49 Vaccinia_virus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 65/3478 79/10654 9.886244818103206e-20 7.649412889984883e-19 3.0987171349891255e-19 10450/9318/6118/5434/5440/902/2074/27339/5430/5436/7515/5982/404672/54107/5441/5438/3978/5431/8450/5435/7316/9978/4331/64708/5433/5111/5426/2966/10980/6119/5437/5427/1161/1642/2965/5985/10920/2033/2068/5439/10987/2071/5984/6233/2067/51426/2873/2968/7311/2967/8533/5983/6117/5981/10714/7874/5424/1022/5432/8178/50813/7314/51138/8451/56655 65 Vaccinia_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 81/3478 108/10654 1.5400945186568628e-19 1.1850171712998639e-18 4.800411569848584e-19 5295/3605/7124/2308/7291/596/9655/2309/3561/7412/7184/356/3593/207/3684/9021/7422/3553/2625/6624/4582/5743/3091/4318/4312/3383/301/6097/6657/6778/3576/332/3688/4313/3565/58480/4985/6774/5443/1026/3718/6772/8651/4609/149233/4988/1901/3552/79923/3717/598/2247/3320/4843/2335/595/6288/7157/3716/2353/604/6347/7076/7040/6935/3687/51561/3570/7431/5008/3312/7297/3569/3162/1278/4170/3689/3586/4692/3596/3598 81 Vaccinia_virus R-HSA-4641257 Degradation of AXIN 50/3478 55/10654 2.0002121582165254e-19 1.5305490823922033e-18 6.200134226981146e-19 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/64750/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/8312/5710/5702/5719/5704/6233/5716/7311/5694/5693/5721/5696/5691/7314 50 Vaccinia_virus R-HSA-4086400 PCP/CE pathway 72/3478 92/10654 2.4108342274683193e-19 1.8346183544195726e-18 7.431894986932413e-19 57154/5718/5689/1173/5684/5720/5579/5682/5700/122706/5707/1856/5690/1212/5578/5717/9491/5582/50855/23198/409/143471/5706/7471/5705/10197/64750/7316/10213/5709/5695/54361/5216/5714/9861/5715/5881/5711/5701/5688/5687/5685/5683/5698/5708/5880/5692/5686/5713/5699/23002/5710/5702/5719/5704/6233/1855/7474/5716/1857/7311/1213/387/1211/5694/5693/5721/5696/6259/5691/7314/5879 72 Vaccinia_virus R-HSA-5358346 Hedgehog ligand biogenesis 56/3478 65/10654 4.538386245887021e-19 3.416122255735611e-18 1.3838443186829417e-18 5718/5689/5684/5720/5682/5700/122706/5707/10956/5690/5717/9491/23198/143471/5706/5705/10197/84447/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/6400/5710/5702/5719/6868/5704/6233/5716/7311/147111/6469/5694/5693/5721/5696/5691/5034/7314 56 Vaccinia_virus R-HSA-9614085 FOXO-mediated transcription 56/3478 65/10654 4.538386245887021e-19 3.416122255735611e-18 1.3838443186829417e-18 5105/2308/27113/857/2290/2309/57060/10018/4802/356/7532/207/10971/4303/23410/1027/7295/2810/4287/6720/1649/7534/5934/3484/114907/4800/5443/1026/901/84676/4089/8850/1647/9314/10370/1387/4088/2908/10628/10000/6794/2033/4852/4801/3630/3066/3065/6648/4087/56729/208/604/23411/25942/7529/10891 56 Vaccinia_virus R-HSA-5696398 Nucleotide Excision Repair 82/3478 111/10654 4.608850123087822e-19 3.450409416473856e-18 1.3977337784385826e-18 10450/9318/6118/5434/5440/902/2074/27339/5430/83444/5436/7515/5982/404672/54107/6613/5441/7336/86/5438/3978/5431/8450/5435/54778/7316/9978/4331/64708/5433/5111/5426/1643/2966/10980/6119/7341/5437/5427/1161/1642/2965/5985/10920/2033/142/2068/5439/10987/2071/5984/7329/6233/2067/51426/2873/2968/7311/2967/6612/60/8533/5887/5983/6117/7334/5981/10714/7874/5424/1022/5432/8178/5886/50813/7508/7314/51138/8451/8554/7528/56655 82 Vaccinia_virus R-HSA-9009391 Extra-nuclear estrogen signaling 63/3478 77/10654 6.426223462054839e-19 4.785118008035458e-18 1.9384137551076566e-18 5295/2788/5170/596/5590/1839/4893/6464/685/857/5290/54331/2309/5747/59345/2770/207/1903/5594/2069/6722/1027/3315/10681/51764/94235/4318/2100/4313/1950/55970/2792/346562/6714/2099/8503/2793/10000/3320/2785/4846/595/2783/2784/2782/2786/2771/208/7514/1385/2353/1956/5296/3845/3276/3265/801/3480/2791/2773/5595/2790/2787 63 Vaccinia_virus R-HSA-176187 Activation of ATR in response to replication stress 37/3478 37/10654 9.014654420894674e-19 6.676629076438033e-18 2.7046500457848923e-18 1017/4172/6118/5000/8318/23594/5883/8317/5982/63967/4173/545/4174/993/84515/4171/4998/6119/3364/10926/144715/5985/990/995/84126/4175/1111/5984/55388/23595/5983/6117/5001/5884/5810/4999/4176 37 Vaccinia_virus R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 42/3478 44/10654 1.4230555383706604e-18 1.0373325898122973e-17 4.202152919399236e-18 23368/834/27113/79370/9540/8793/55240/835/58484/3486/355/55367/472/8794/332/64065/5366/124446/8797/84883/147923/5876/1387/51499/843/94241/8738/7157/8626/604/63970/7161/839/581/7159/637/317/10397/8795/665/5875/27166 42 Vaccinia_virus R-HSA-69231 Cyclin D associated events in G1 42/3478 44/10654 1.4230555383706604e-18 1.0373325898122973e-17 4.202152919399236e-18 8454/25/894/1019/902/1029/7027/1027/6500/5925/5934/7316/1869/1875/5753/4331/1026/5933/6714/1871/1031/5519/4067/3717/6502/1021/1874/595/5520/896/1870/6233/1032/1030/7311/5518/1163/1022/1028/7314/5515/5516 42 Vaccinia_virus R-HSA-69236 G1 Phase 42/3478 44/10654 1.4230555383706604e-18 1.0373325898122973e-17 4.202152919399236e-18 8454/25/894/1019/902/1029/7027/1027/6500/5925/5934/7316/1869/1875/5753/4331/1026/5933/6714/1871/1031/5519/4067/3717/6502/1021/1874/595/5520/896/1870/6233/1032/1030/7311/5518/1163/1022/1028/7314/5515/5516 42 Vaccinia_virus R-HSA-5673001 RAF/MAP kinase cascade 148/3478 249/10654 1.544333346166457e-18 1.1198438138432162e-17 4.536399413098493e-18 5923/5718/5689/1839/5684/2674/4893/6464/6711/685/5720/3667/71/5682/1844/5604/2904/3561/5747/153090/5700/3815/122706/5707/283455/8844/10048/3674/7094/5690/5594/2069/5717/8074/9491/23198/409/5908/7414/10817/143471/5706/2064/5921/5705/10197/8452/54518/5528/7316/10213/5709/673/9978/1950/3560/5695/1852/4233/84078/3718/5714/22866/6714/5605/9861/5715/5037/5519/5711/10256/2261/5701/5688/5159/5687/3558/3717/2247/5685/2244/8649/5683/5698/5708/3084/145957/5692/5686/5713/2335/2534/3690/408/5699/1445/5710/2264/5702/2066/5894/5719/1742/6654/9542/5704/6233/5527/2885/10718/6709/3716/5716/88/2266/8660/7311/8826/5906/5518/2243/7450/1956/60/5536/4140/3845/5694/3265/3559/369/801/4763/5693/5924/5721/8682/5696/5691/5245/7529/5156/7314/1846/28956/5595/5515/5516 148 Vaccinia_virus R-HSA-5678895 Defective CFTR causes cystic fibrosis 53/3478 61/10654 1.8194825134068974e-18 1.3124912922232047e-17 5.316799230514673e-18 5718/5689/5684/5720/5682/5700/122706/5707/10956/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/6400/5710/5702/5719/5704/6233/5716/7311/11160/5694/5693/5721/5696/5691/7314 53 Vaccinia_virus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 36/3478 36/10654 2.780871604911667e-18 1.9955995714003412e-17 8.084017264346433e-18 4893/71/5604/283455/8844/3674/7094/5594/409/5908/7414/54518/673/22866/6714/5605/5037/10256/2244/2335/3690/408/1445/5894/2266/8826/5906/2243/7450/60/4140/3845/3265/369/7529/5595 36 Vaccinia_virus R-HSA-5658442 Regulation of RAS by GAPs 57/3478 68/10654 3.275698749311659e-18 2.338578746286932e-17 9.473398987428726e-18 5718/5689/5684/4893/5720/5682/153090/5700/122706/5707/5690/5717/9491/23198/143471/5706/5921/5705/10197/8452/7316/10213/5709/9978/5695/84078/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/5716/7311/3845/5694/3265/4763/5693/5721/5696/5691/7314 57 Vaccinia_virus R-HSA-76002 Platelet activation, signaling and aggregation 153/3478 262/10654 4.0763643674532e-18 2.895263922524452e-17 1.1728486951970611e-17 5295/2788/151/928/5170/5777/5590/351/1072/6464/5321/5290/54331/5005/7018/5579/2153/5770/5291/5340/5747/59345/3937/64805/2770/5336/2316/207/3674/813/7094/7422/5578/5594/5582/10681/409/5908/388/7414/51764/7277/94235/10451/3708/5583/1277/29106/7534/5196/3827/150/54518/1950/335/55970/2621/308/5216/6850/2767/2792/5768/346562/6714/710/6694/152/6647/7273/22927/8503/146850/1432/27154/2793/226/197/4067/23533/374354/2244/1893/81/5265/3309/5880/7078/9948/2335/5294/2534/3690/408/2785/391/334/2783/2784/2768/1445/2782/87/8525/998/2776/5894/3481/5478/2786/2771/2/10487/6654/2885/1398/5473/7410/5580/88/2266/7409/8407/1675/5906/3932/7076/3479/2243/7450/387/5296/7040/9564/10916/213/5660/801/350/5781/7057/1278/2791/1609/5627/2773/967/5879/5595/2790/5054/2787/10672 153 Vaccinia_virus R-HSA-9012852 Signaling by NOTCH3 45/3478 49/10654 5.047375568460092e-18 3.566640388937361e-17 1.444818033291745e-17 23129/142678/2648/23462/4904/55534/3280/182/84441/23385/10460/10046/7316/1950/4854/3714/54492/102/6772/5664/10320/11060/22938/8850/1387/2173/26508/2033/9148/9794/83464/6233/23493/7311/57534/1956/54567/388585/55851/51107/3516/4851/5663/28514/7314 45 Vaccinia_virus R-HSA-4420097 VEGFA-VEGFR2 Pathway 74/3478 99/10654 8.058134242382094e-18 5.665236510507208e-17 2.2949428539618793e-17 5295/26999/5170/4688/5590/4893/857/5290/5335/71/558/5579/5291/1495/1499/6461/5747/4690/5567/10006/207/7422/10458/5578/5568/3315/10451/3708/5921/1793/1500/9047/10152/6714/64223/5566/1003/1432/10000/3320/2534/9475/3690/4846/3728/5603/998/208/1398/7410/5580/2475/7409/23191/6093/3685/9844/2185/3791/387/60/5296/9564/3845/5600/3265/5058/6300/801/3071/63916/5829/5879/253260 74 Vaccinia_virus R-HSA-3371556 Cellular response to heat stress 68/3478 89/10654 2.390820032495112e-17 1.6723665378816817e-16 6.77462561041943e-17 23165/3303/6118/5903/573/55706/7175/9631/7531/1915/5594/3308/84335/10049/348995/1410/10013/545/79023/472/57122/23636/3337/3313/10762/23511/3305/53371/9532/23279/4927/9688/7415/79902/64223/91582/6119/9883/2932/1387/57805/3310/3309/3320/2033/7266/6767/9531/8086/23225/3326/2475/3306/9972/23411/8021/9529/6117/6396/129401/3304/3312/57521/55746/2288/8480/10728/5595 68 Vaccinia_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 59/3478 73/10654 2.6179608549183384e-17 1.8220481326944214e-16 7.380974005138717e-17 57154/5590/892/7027/7321/51377/6497/10273/4738/5045/50855/23370/64750/50848/7323/8239/54778/7316/1875/9611/5501/9612/1024/6667/5933/4092/4609/4089/22938/23327/867/8812/7046/4088/1874/142/905/3065/2280/9958/9040/4087/5499/6233/7514/7048/1025/1030/7311/56288/25937/387/7040/57530/904/5500/7314/4221/5054 59 Vaccinia_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 34/3478 34/10654 2.6447760877964803e-17 1.8315074407990626e-16 7.419292919976442e-17 7321/9140/29110/57506/9636/54476/7706/84166/8887/7323/9474/7316/3093/23586/7322/7128/64135/54941/83737/3661/9246/51191/6233/7311/55593/84282/7318/79671/5094/7187/5300/9641/1540/7314 34 Vaccinia_virus R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 45/3478 50/10654 3.450443030752015e-17 2.3775440784037515e-16 9.631244490132623e-17 5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/9902/5704/5716/5694/5693/5721/5696/5691 45 Vaccinia_virus R-HSA-166658 Complement cascade 50/3478 58/10654 3.515262698172044e-17 2.4102172460239015e-16 9.763600928221467e-17 5648/727/629/5199/10584/1991/722/3004/930/27202/1378/3078/7448/10747/1604/1361/1401/717/966/712/710/81494/3075/716/715/78989/1380/3426/2220/721/975/1369/731/725/728/10878/10877/1675/719/732/713/2219/720/4179/8547/714/4153/5627/1370/718 50 Vaccinia_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 48/3478 55/10654 5.216583662013873e-17 3.5590977201424696e-16 1.4417625573520324e-16 1147/834/596/351/4790/6885/9447/842/10392/8767/835/58484/7295/330/23118/29108/841/8517/7316/7335/5970/64127/7128/1432/329/837/598/10628/3656/5603/10454/83737/3654/7189/6233/3326/4210/7311/114548/5600/7334/1540/3551/6300/5608/4791/7314/257397 48 Vaccinia_virus R-HSA-73894 DNA Repair 182/3478 334/10654 5.455136886659845e-17 3.703610092168571e-16 1.500303385237202e-16 10450/9318/8467/1017/7014/6118/2176/80010/25/25913/3838/2237/5434/5440/5893/4436/83990/151987/902/5888/4350/9156/2074/5883/322/1763/328/27339/7486/5430/10111/83444/27343/4913/5436/7320/51588/7520/51720/2956/675/7515/5982/63967/404672/54107/5531/51548/4292/9636/11200/545/472/6613/5441/7706/7336/86/5438/3978/3981/580/5431/11073/5591/29086/8450/5435/54778/7316/9978/11201/116028/890/6996/4331/64708/8314/5433/641/5111/5426/9100/1643/2966/7415/5395/10980/64421/9656/6119/51455/3364/22976/7341/10524/4683/5437/51008/5427/144715/1161/1642/2965/5985/10920/25898/2033/165918/29089/84126/142/7398/2068/1111/5439/10987/2071/7157/8900/5984/4595/7329/4255/9246/79728/8924/57599/6233/2067/51426/2873/2968/672/2138/5932/7158/7311/6047/9025/2189/7318/4968/2967/79184/6612/23030/55247/60/5536/8533/7156/5887/5983/6117/2175/5599/7334/10973/5981/10714/7874/2547/5884/5810/5424/1022/5432/8178/2188/83695/5886/55183/50813/7508/7314/51514/51138/8451/8554/7528/56655 182 Vaccinia_virus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 54/3478 65/10654 5.690737069739946e-17 3.8447174837023535e-16 1.5574648822446169e-16 10450/6118/5434/5440/902/2074/27339/5430/5436/7515/5982/404672/54107/5441/5438/3978/5431/8450/5435/7316/9978/4331/5433/5111/5426/2966/6119/5437/5427/1161/1642/2965/5985/2033/2068/5439/2071/5984/6233/51426/2968/7311/2967/5983/6117/5981/10714/7874/5424/1022/5432/7314/8451/56655 54 Vaccinia_virus R-HSA-68962 Activation of the pre-replicative complex 33/3478 33/10654 8.153894580112147e-17 5.48210873468705e-16 2.220759229023901e-16 1017/4172/6118/5000/8318/23594/8317/54107/4173/5557/5422/4174/84515/5426/4171/51053/4998/6119/10926/5427/990/4175/81620/55388/29935/23595/23649/6117/5001/5558/4999/4176/56655 33 Vaccinia_virus R-HSA-5674135 MAP2K and MAPK activation 38/3478 40/10654 1.0671453228635457e-16 7.140078609497637e-16 2.8923898148297476e-16 4893/71/5604/283455/8844/3674/7094/5594/409/5908/7414/54518/673/22866/6714/5605/5037/10256/2244/8649/2335/3690/408/1445/5894/2266/8826/5906/2243/7450/60/4140/3845/3265/369/7529/28956/5595 38 Vaccinia_virus R-HSA-450294 MAP kinase activation 53/3478 64/10654 1.4646241051206041e-16 9.705762610488215e-16 3.931728270104669e-16 8454/1147/3725/8945/5601/4790/6885/5606/5604/10392/8767/5594/6500/23118/8517/5528/7316/79155/7335/5519/64127/5598/1432/466/23291/5602/3656/6195/10454/3654/7189/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/6416/5608/51231/7314/1846/5595/5515/257397/5516 53 Vaccinia_virus R-HSA-4608870 Asymmetric localization of PCP proteins 53/3478 64/10654 1.4646241051206041e-16 9.705762610488215e-16 3.931728270104669e-16 57154/5718/5689/5684/5720/5682/5700/122706/5707/1856/5690/5717/9491/50855/23198/143471/5706/5705/10197/64750/7316/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/6233/7474/5716/7311/5694/5693/5721/5696/5691/7314 53 Vaccinia_virus R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 45/3478 51/10654 2.005082492546123e-16 1.3223996438935143e-15 5.356937185599416e-16 5718/5689/5684/1728/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/5694/5693/5721/5696/5691 45 Vaccinia_virus R-HSA-194138 Signaling by VEGF 76/3478 107/10654 3.667730645620814e-16 2.4074914427416247e-15 9.752558913025162e-16 5295/26999/5170/4688/5590/4893/857/5290/5335/71/558/5579/5291/1495/1499/6461/5747/4690/5567/10006/207/7422/10458/5578/5568/3315/10451/3708/5921/1793/1500/9047/10152/6714/64223/5566/1003/1432/2321/10000/3320/2534/9475/3690/4846/3728/5603/998/208/1398/7410/5580/2324/2475/7409/23191/6093/3685/9844/2185/3791/387/60/5296/9564/3845/5600/3265/5058/6300/801/3071/63916/5829/5879/253260 76 Vaccinia_virus R-HSA-2682334 EPH-Ephrin signaling 68/3478 92/10654 4.719866750088292e-16 3.0834978532416437e-15 1.2491007834146274e-15 64283/1173/1072/3984/71/2042/2904/5747/4627/1212/3985/7074/10627/10451/23385/4318/5921/6383/6453/4313/10398/2041/102/2045/10094/6714/5664/4637/1943/4067/2044/2043/285220/79784/2534/9475/1946/6386/998/1948/4628/2048/8976/83464/7525/1942/7410/10097/6093/8997/1759/1213/103910/387/1211/60/8874/10095/55851/51107/3265/25791/5058/10109/5663/4629/1969/5879 68 Vaccinia_virus R-HSA-167161 HIV Transcription Initiation 42/3478 47/10654 7.381088623879516e-16 4.689361350492261e-15 1.899623484561942e-15 6884/6875/2963/5434/5440/902/5430/6874/5436/6878/404672/5441/5438/5431/5435/6872/4331/5433/8148/2966/6879/2962/54457/5437/83860/2965/2068/5439/2071/6873/2968/6881/2967/51616/6880/6908/6883/6882/138474/1022/5432/6877 42 Vaccinia_virus R-HSA-167162 RNA Polymerase II HIV Promoter Escape 42/3478 47/10654 7.381088623879516e-16 4.689361350492261e-15 1.899623484561942e-15 6884/6875/2963/5434/5440/902/5430/6874/5436/6878/404672/5441/5438/5431/5435/6872/4331/5433/8148/2966/6879/2962/54457/5437/83860/2965/2068/5439/2071/6873/2968/6881/2967/51616/6880/6908/6883/6882/138474/1022/5432/6877 42 Vaccinia_virus R-HSA-73776 RNA Polymerase II Promoter Escape 42/3478 47/10654 7.381088623879516e-16 4.689361350492261e-15 1.899623484561942e-15 6884/6875/2963/5434/5440/902/5430/6874/5436/6878/404672/5441/5438/5431/5435/6872/4331/5433/8148/2966/6879/2962/54457/5437/83860/2965/2068/5439/2071/6873/2968/6881/2967/51616/6880/6908/6883/6882/138474/1022/5432/6877 42 Vaccinia_virus R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 42/3478 47/10654 7.381088623879516e-16 4.689361350492261e-15 1.899623484561942e-15 6884/6875/2963/5434/5440/902/5430/6874/5436/6878/404672/5441/5438/5431/5435/6872/4331/5433/8148/2966/6879/2962/54457/5437/83860/2965/2068/5439/2071/6873/2968/6881/2967/51616/6880/6908/6883/6882/138474/1022/5432/6877 42 Vaccinia_virus R-HSA-75953 RNA Polymerase II Transcription Initiation 42/3478 47/10654 7.381088623879516e-16 4.689361350492261e-15 1.899623484561942e-15 6884/6875/2963/5434/5440/902/5430/6874/5436/6878/404672/5441/5438/5431/5435/6872/4331/5433/8148/2966/6879/2962/54457/5437/83860/2965/2068/5439/2071/6873/2968/6881/2967/51616/6880/6908/6883/6882/138474/1022/5432/6877 42 Vaccinia_virus R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 42/3478 47/10654 7.381088623879516e-16 4.689361350492261e-15 1.899623484561942e-15 6884/6875/2963/5434/5440/902/5430/6874/5436/6878/404672/5441/5438/5431/5435/6872/4331/5433/8148/2966/6879/2962/54457/5437/83860/2965/2068/5439/2071/6873/2968/6881/2967/51616/6880/6908/6883/6882/138474/1022/5432/6877 42 Vaccinia_virus R-HSA-2122948 Activated NOTCH1 Transmits Signal to the Nucleus 31/3478 31/10654 7.745723935730944e-16 4.898551438807013e-15 1.9843647477743778e-15 142678/113878/23220/182/409/23385/7316/3714/8650/54492/1272/102/5664/8788/9148/408/83737/92737/6868/83464/6233/7311/1840/57534/54567/55851/51107/4851/5663/28514/7314 31 Vaccinia_virus R-HSA-167172 Transcription of the HIV genome 57/3478 73/10654 1.6740462230930748e-15 1.0538881904472312e-14 4.269218358414396e-15 6884/6875/2963/5434/5440/902/5430/6874/5436/6878/404672/6749/5441/5438/5431/5435/4686/6872/4331/5433/8148/2966/8731/6879/9150/2962/54457/5437/8812/83860/8732/2965/905/2068/5439/2071/6873/6827/2968/1025/6881/2967/51616/6880/6908/11198/904/6883/6829/51497/6882/138474/1022/5432/22916/8178/6877 57 Vaccinia_virus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 63/3478 84/10654 1.7317827626469394e-15 1.0853027720660684e-14 4.3964763633761305e-15 9318/6118/902/83444/7515/5982/404672/54107/6613/7336/86/3978/8450/54778/7316/9978/4331/64708/5111/5426/1643/2966/10980/6119/7341/5427/1642/2965/5985/10920/142/2068/10987/2071/5984/7329/6233/2067/51426/2873/2968/7311/2967/6612/60/8533/5887/5983/6117/7334/5981/10714/5424/1022/5886/50813/7508/7314/51138/8451/8554/7528/56655 63 Vaccinia_virus R-HSA-8848021 Signaling by PTK6 46/3478 54/10654 1.7503660937023132e-15 1.087110780169374e-14 4.403800462323969e-15 120892/1017/1839/1019/4893/685/5770/207/2909/9021/2069/27043/1027/898/3091/116985/2064/5921/10657/1793/7316/1950/5753/6774/867/6421/2908/3084/145957/595/2066/9542/6233/1398/10718/9844/7311/387/1956/9564/3845/3265/63916/5829/7314/5879 46 Vaccinia_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 46/3478 54/10654 1.7503660937023132e-15 1.087110780169374e-14 4.403800462323969e-15 120892/1017/1839/1019/4893/685/5770/207/2909/9021/2069/27043/1027/898/3091/116985/2064/5921/10657/1793/7316/1950/5753/6774/867/6421/2908/3084/145957/595/2066/9542/6233/1398/10718/9844/7311/387/1956/9564/3845/3265/63916/5829/7314/5879 46 Vaccinia_virus R-HSA-6782135 Dual incision in TC-NER 53/3478 66/10654 1.8799946268545445e-15 1.1624073920506894e-14 4.708821128352783e-15 10450/6118/5434/5440/902/2074/27339/5430/5436/5982/404672/54107/5441/5438/5431/8450/5435/7316/9978/4331/5433/5111/5426/2966/6119/5437/5427/1161/1642/2965/5985/2033/2068/5439/2071/5984/6233/2067/51426/2968/7311/2967/5983/6117/5981/10714/7874/5424/1022/5432/7314/8451/56655 53 Vaccinia_virus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 59/3478 77/10654 2.518579709163923e-15 1.5503257320853482e-14 6.280247882967818e-15 1912/23165/5893/5903/55706/7175/9631/1029/7486/8535/51564/6045/51588/80012/348995/79023/6613/57122/23636/10762/5885/23511/53371/6996/1911/641/6672/23279/4927/9688/79902/9656/9883/7341/84733/165918/8243/9126/57332/142/8086/7329/5371/8924/23225/672/9972/6612/9063/8021/6117/6396/648/129401/55746/8480/7508/6015/8554 59 Vaccinia_virus R-HSA-168325 Viral Messenger RNA Synthesis 39/3478 43/10654 2.560719587821259e-15 1.569290543863913e-14 6.357072847269357e-15 23165/2963/5434/5440/5903/55706/7175/9631/5430/5436/348995/79023/5441/57122/23636/5438/10762/5431/23511/5435/53371/5433/23279/4927/9688/79902/2962/9883/5437/5439/8086/23225/9972/8021/6396/129401/5432/55746/8480 39 Vaccinia_virus R-HSA-5685938 HDR through Single Strand Annealing (SSA) 35/3478 37/10654 2.6788729292358935e-15 1.6344665229038382e-14 6.621095623847583e-15 6118/80010/25/5893/83990/5888/9156/5883/1763/7486/10111/5982/545/472/580/11073/116028/641/6119/3364/10524/4683/144715/5985/84126/5984/2067/672/5932/7156/5983/6117/5884/5810/83695 35 Vaccinia_virus R-HSA-1236974 ER-Phagosome pathway 62/3478 83/10654 4.031074470171165e-15 2.448700939117133e-14 9.919495349036154e-15 23643/1147/5718/5689/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/811/143471/5706/5705/10333/10197/7099/8517/4615/7316/10213/5709/5695/7096/5714/9861/5715/5711/5701/5688/5687/5685/5683/929/5698/5708/5692/5686/5713/114609/5699/2923/5710/5702/695/5719/5704/6233/5716/7311/5694/7097/3551/5693/5721/5696/5691/7314 62 Vaccinia_virus R-HSA-216083 Integrin cell surface interactions 63/3478 85/10654 4.5690062928947996e-15 2.763350967536811e-14 1.11941179228358e-14 3675/8174/1286/1287/3371/1282/1294/960/375790/7412/1299/91522/3674/256076/3684/1284/1305/3383/3678/1277/1280/1289/7448/1307/6696/50848/1300/3688/3672/1298/3695/1281/1297/1290/999/2244/682/2335/3690/3694/2200/1295/1288/2266/3685/1292/4060/2243/3791/7450/50509/1293/3687/1285/131873/80781/7057/1278/3689/1296/3676/1291/3655 63 Vaccinia_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 45/3478 53/10654 4.613088680743326e-15 2.7778816620997853e-14 1.1252980626252597e-14 23368/27113/596/10018/7531/1029/7027/842/572/7532/207/10971/5594/7533/2810/841/7534/1869/8655/6774/54205/4836/5366/598/56616/836/10000/5534/3002/7157/90427/8626/208/7161/840/331/581/5599/7159/637/317/140735/7529/578/5595 45 Vaccinia_virus R-HSA-390466 Chaperonin-mediated protein folding 68/3478 95/10654 7.107843375588031e-15 4.2616290368785384e-14 1.7263524808331832e-14 2788/10694/84617/9134/8841/54331/59345/1459/2770/2781/51807/8237/10575/10382/26224/10681/898/51764/1460/7277/94235/10381/7278/112714/2775/10517/7203/10576/908/55970/6774/1457/2792/26272/346562/2793/26270/6950/7846/113457/347733/2785/10376/55294/2783/26190/2784/10238/2782/7157/2786/2771/10574/6468/10564/10383/60/54461/84790/22948/26234/10693/2791/7280/84261/2773/2790/2787 68 Vaccinia_virus R-HSA-72086 mRNA Capping 29/3478 29/10654 7.3522211780114465e-015 4.38914928083873e-14 1.778009930980082e-14 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/4686/4331/5433/2966/8731/2962/5437/8732/2965/2068/5439/2071/2968/2967/6829/1022/5432/22916 29 Vaccinia_virus R-HSA-168638 NOD1/2 Signaling Pathway 34/3478 36/10654 7.818650304595613e-15 4.646549104867528e-14 1.8822805798171324e-14 1147/834/6885/842/10392/8767/835/330/23118/841/8517/7316/7335/64127/7128/1432/329/837/3656/5603/10454/83737/3654/7189/6233/7311/5600/7334/1540/3551/6300/5608/7314/257397 34 Vaccinia_virus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 54/3478 69/10654 7.85048729631048e-15 4.646549104867528e-14 1.8822805798171324e-14 23165/3303/6118/5903/573/55706/7175/9631/7531/5594/3308/10049/348995/545/79023/472/57122/23636/3337/3313/10762/23511/3305/53371/9532/23279/4927/9688/79902/91582/6119/9883/2932/57805/3310/3309/7266/6767/9531/8086/23225/3306/9972/23411/8021/9529/6117/6396/129401/3304/3312/55746/8480/5595 54 Vaccinia_virus R-HSA-8878171 Transcriptional regulation by RUNX1 135/3478 239/10654 1.5590055757637175e-14 9.188181797586164e-14 3.722060344376535e-14 55904/1912/5718/6595/9070/5689/27161/25/894/5684/4773/5720/902/2624/11091/5579/6597/5682/6929/1459/5700/122706/5707/8535/3674/6045/9021/5690/2625/57690/5717/5929/9491/23198/27327/80012/1460/1378/143471/3958/6938/5706/6598/5705/10197/6599/192670/200845/5196/86/100506658/7316/10213/5709/865/5695/28996/10398/7082/1457/4331/1911/6603/10413/5714/23309/6714/2099/9861/5715/8850/5711/5701/5688/1387/84733/5687/3558/5685/5683/8289/5698/5708/5692/5686/5713/2033/1021/6602/57332/595/50943/5699/4602/8312/5710/3458/5702/192669/3065/83737/861/896/5719/5371/23112/5704/6233/5716/7311/7161/860/58508/25942/9739/4343/648/3276/5694/6601/3559/23466/26523/5781/7057/1022/5693/5721/23429/4297/5696/5691/55193/7314/6015 135 Vaccinia_virus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 45/3478 54/10654 1.892670161594848e-14 1.1107407516139257e-13 4.499523622346361e-14 10450/9318/5434/5440/902/2074/27339/5430/5436/404672/5441/5438/5431/8450/5435/7316/9978/4331/64708/5433/2966/10980/5437/1161/1642/2965/10920/2033/2068/5439/10987/2071/6233/2873/2968/7311/2967/8533/7874/1022/5432/50813/7314/51138/8451 45 Vaccinia_virus R-HSA-350054 Notch-HLH transcription pathway 28/3478 28/10654 2.2644841228275253e-14 1.3233377679814864e-13 5.360737452662985e-14 8841/79718/79885/2648/9734/55869/51564/55534/84441/10013/10046/83933/4854/9611/9759/9612/10014/22938/8850/1387/6907/4855/4853/3066/3065/9794/3516/4851 28 Vaccinia_virus R-HSA-420499 Class C/3 (Metabotropic glutamate/pheromone receptors) 35/3478 38/10654 2.3241855296738803e-14 1.3525197305034974e-13 5.4789512928623536e-14 2913/50833/338398/5726/2916/259293/259287/2550/50836/50832/846/2918/80835/259294/259290/2912/259295/9568/54429/80834/259292/50834/259285/50838/2914/2917/50831/50839/83756/259296/259289/50835/50840/259286/50837 35 Vaccinia_virus R-HSA-5632684 Hedgehog 'on' state 62/3478 85/10654 2.6528165957241628e-14 1.5373016673966383e-13 6.22748841894287e-14 57154/5718/5689/5684/5720/2735/5682/5700/122706/5707/11127/22873/1452/5690/5717/9491/23198/409/143471/5706/5705/10197/64750/8452/7316/10213/5709/9978/5695/5727/8650/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/408/5699/5710/5702/83737/5719/5704/6233/5716/7311/6469/5694/5693/5721/5696/5691/7314 62 Vaccinia_virus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 51/3478 65/10654 3.678291818260399e-14 2.1226809034544385e-13 8.598813768126284e-14 2176/3725/2963/5434/5440/4436/8621/902/5430/5436/404672/6749/4292/545/472/5441/5438/5431/5435/4331/5433/1643/2966/5395/9150/2962/9656/5437/8812/2965/51755/905/2068/1111/5439/2071/7157/6827/2968/672/1025/2353/2967/1386/11198/904/6829/51497/1022/5432/8178 51 Vaccinia_virus R-HSA-186797 Signaling by PDGF 47/3478 58/10654 3.9551937583263146e-14 2.2730055416107658e-13 9.20776708096932e-14 5295/1286/1287/1282/4893/5290/5335/5291/5340/4690/1299/256076/1284/5045/5921/1280/1289/6778/6696/6776/1298/6774/6772/6714/1281/1297/1290/2889/5159/6654/2885/1398/1292/50509/5296/1293/9564/3845/1285/131873/6777/3265/1399/5781/7057/1291/5156 47 Vaccinia_virus R-HSA-8939211 ESR-mediated signaling 127/3478 223/10654 4.1322824968411476e-14 2.3649633298037147e-13 9.580280864794832e-14 5295/2788/5170/27161/3725/2963/3838/596/5434/5440/5590/1839/4893/6464/685/857/5290/54331/7090/5241/2309/9687/5747/59345/5430/2770/207/5436/1903/2625/57690/5594/2069/6722/1027/3315/10681/27327/51764/94235/4318/5441/5481/192670/200845/5438/5431/5885/2100/5435/4313/1950/865/55970/5469/1655/5433/6667/2792/346562/6714/2099/4609/2962/7391/8850/8503/10524/1387/5437/2793/10000/3320/2033/8243/2785/4846/9126/595/2783/4602/2784/8312/2782/5439/192669/3065/2066/861/23028/2786/23112/2771/208/10498/3326/7514/1385/1025/2353/10499/23030/1386/6908/1956/5536/5296/4343/3845/904/3276/3265/26523/801/8202/5432/8648/3480/2791/2288/2773/10728/5595/2790/2787/7528/6387 127 Vaccinia_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 34/3478 37/10654 6.606946055867248e-14 3.765687361060139e-13 1.525450399730233e-13 1017/5170/1029/207/11200/472/117584/639/7316/890/80196/983/64223/4194/5519/1616/9099/10000/900/7157/8900/208/6233/5527/2475/7311/5518/7874/51230/7314/253260/4193/5515/5516 34 Vaccinia_virus R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 27/3478 27/10654 6.973246239724147e-14 3.942018792660385e-13 1.5968808789572374e-13 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/4331/5433/2966/8731/2962/5437/8732/2965/2068/5439/2071/2968/2967/6829/1022/5432 27 Vaccinia_virus R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 27/3478 27/10654 6.973246239724147e-14 3.942018792660385e-13 1.5968808789572374e-13 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/4331/5433/2966/8731/2962/5437/8732/2965/2068/5439/2071/2968/2967/6829/1022/5432 27 Vaccinia_virus R-HSA-448424 Interleukin-17 signaling 54/3478 72/10654 1.8303391348360124e-13 1.0304958137186492e-12 4.1744576759417825e-13 8454/3605/1147/3725/8945/5601/4790/6885/5606/5604/10392/8767/5594/6500/23118/8517/5528/7316/79155/7335/5519/64127/5598/1432/466/23291/5602/3656/6195/10454/3654/7189/5609/6233/1385/2353/6196/7311/5518/1386/6197/5599/5600/7334/3551/6416/5608/51231/7314/1846/5595/5515/257397/5516 54 Vaccinia_virus R-HSA-6804757 Regulation of TP53 Degradation 33/3478 36/10654 1.8735627099480934e-13 1.0505604669142144e-12 4.255738011516444e-13 1017/5170/1029/207/11200/472/117584/7316/890/80196/983/64223/4194/5519/1616/9099/10000/900/7157/8900/208/6233/5527/2475/7311/5518/7874/51230/7314/253260/4193/5515/5516 33 Vaccinia_virus R-HSA-1980145 Signaling by NOTCH2 31/3478 33/10654 1.9229997389191368e-13 1.069620336708034e-12 4.3329480483783544e-13 142678/55534/3280/182/84441/23385/10046/7316/3714/54492/1272/102/5664/2033/9148/3002/4853/9794/83464/6233/1385/7311/57534/54567/388585/55851/51107/3516/5663/28514/7314 31 Vaccinia_virus R-HSA-2559585 Oncogene Induced Senescence 31/3478 33/10654 1.9229997389191368e-13 1.069620336708034e-12 4.3329480483783544e-13 1019/1029/7027/57690/5594/27327/5925/192670/7316/2114/1869/6667/1871/4194/1031/1021/192669/7157/23112/1870/6233/1032/1030/7311/3397/4343/26523/2113/7314/5595/4193 31 Vaccinia_virus R-HSA-2559583 Cellular Senescence 113/3478 195/10654 2.1365746187628322e-13 1.1836623387946091e-12 4.794923249686693e-13 1912/1017/7014/3725/25913/9134/1019/5601/11065/4790/5606/3159/246184/7290/1029/7027/7321/2146/10111/8535/6045/8697/57690/5594/1027/27327/80012/898/5931/7295/5925/1051/472/79813/192670/3576/3490/8550/8881/29855/7316/2114/1869/890/6774/5970/1026/1911/6667/1871/51433/4194/1031/5598/3552/5928/1432/10524/84733/4683/5602/23512/1021/119504/57332/6195/25842/192669/7157/8900/51529/23135/7324/64682/29945/10393/8091/23112/5609/1870/6233/51434/1032/2353/1030/51343/6196/7311/25906/3397/57634/4343/8726/6197/29882/5599/648/5600/23466/4217/26523/3456/2113/6416/5608/3569/10919/7314/23523/996/6015/5595/4193 113 Vaccinia_virus R-HSA-1236394 Signaling by ERBB4 46/3478 58/10654 3.2794108784549743e-13 1.8095554050438804e-12 7.330366945760122e-13 5295/1839/4893/6464/685/5290/5241/2069/23118/51741/23385/348/6776/7316/1950/9611/11059/4734/10413/6714/2099/5664/2567/3084/145957/2066/83737/6868/3925/6285/1742/6654/9542/83464/6233/2885/10718/7311/1956/3845/55851/51107/3265/5663/7314/6387 46 Vaccinia_virus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 34/3478 38/10654 4.3010410528510694e-13 2.3638658167455284e-12 9.575834925520553e-13 23165/5903/55706/7175/9631/51588/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/7341/7428/8086/7329/5987/5371/23225/9972/9063/8021/6396/129401/55746/8480/4193/8554 34 Vaccinia_virus R-HSA-500792 GPCR ligand binding 226/3478 468/10654 5.080344201789981e-13 2.781137043272381e-12 1.126616791992536e-12 2788/729230/151/57007/10316/10803/2913/4544/4543/4889/1880/9283/727/351/11251/7852/7472/9294/54331/3352/8484/50833/1909/338398/5726/117579/283869/338442/59345/2740/4986/23566/6351/2358/2916/64805/6752/259293/6374/1237/5539/259287/1903/2852/2550/84539/50836/1230/50832/5179/3354/6753/846/2841/4886/2919/3577/2918/4987/51289/10681/80835/5368/6754/27202/8862/51764/259294/94235/7471/259290/301/8811/2912/3576/56670/5196/6360/3827/150/1604/5173/56923/3579/2832/2357/4985/27199/2920/2826/55970/2921/2778/1236/5727/2853/6352/140/6751/6376/259295/54361/165140/27198/89780/5443/6010/9568/186/3627/53637/2792/54429/2840/2831/3361/6346/152/1906/5367/80834/10563/134/5540/4988/259292/1901/6370/58191/2793/5030/5697/6755/1524/5733/256933/10663/1129/643/5729/51554/10850/51083/2785/3355/2783/624/3351/2784/4852/2782/1233/6288/6372/6366/185/1241/2786/50834/339403/2861/259285/728/50838/2914/7474/183/10022/5473/4283/6364/8843/719/2847/6363/2359/6373/57121/2917/2833/6347/1268/9290/11255/50831/9170/6469/187/1132/10874/1814/50839/83756/6357/6750/259296/8698/259289/56477/5660/50835/1815/2587/1325/53829/1232/9934/50840/1902/259286/3350/129521/154/1234/50837/2791/1269/59340/1813/50865/4887/2790/718/2787/6387/623 226 Vaccinia_virus R-HSA-418597 G alpha (z) signalling events 40/3478 48/10654 5.55875523756783e-13 3.0310535448942694e-12 1.22785600564594e-12 2788/151/54331/5579/59345/2770/2781/5578/5582/10681/51764/112/94235/114/5583/108/150/113/55970/2778/111/107/2792/346562/152/2793/2785/2783/2784/2782/2786/2771/5580/196883/115/2791/109/2773/2790/2787 40 Vaccinia_virus R-HSA-392451 G beta:gamma signalling through PI3Kgamma 25/3478 25/10654 6.60863230043797e-13 3.561461375916961e-12 1.442720055758115e-12 2788/5170/54331/59345/207/10681/51764/94235/55970/2792/146850/2793/23533/10000/5294/2785/2783/2784/2782/2786/208/387/2791/2790/2787 25 Vaccinia_virus R-HSA-400685 Sema4D in semaphorin signaling 25/3478 25/10654 6.60863230043797e-13 3.561461375916961e-12 1.442720055758115e-12 27289/3984/4627/2909/389/3985/10627/388/2064/5364/10398/4233/9826/4637/23365/79784/9475/4628/6093/10507/103910/387/6237/4629/5879 25 Vaccinia_virus R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus 25/3478 25/10654 6.60863230043797e-13 3.561461375916961e-12 1.442720055758115e-12 142678/4904/182/23385/10460/7316/1950/4854/3714/54492/102/5664/11060/9148/83464/6233/7311/57534/1956/54567/55851/51107/5663/28514/7314 25 Vaccinia_virus R-HSA-1227986 Signaling by ERBB2 41/3478 50/10654 8.167788301354365e-13 4.384646045494495e-12 1.7761857056800803e-12 5295/1839/4893/8065/6464/685/5290/5335/10273/207/5578/10193/2069/2064/7316/1950/5753/51072/6714/10000/3320/3084/145957/2534/2066/208/6654/9542/6233/2885/7525/10718/5580/7311/387/1729/1956/3845/3265/11140/7314 41 Vaccinia_virus R-HSA-391251 Protein folding 68/3478 101/10654 8.242197637286885e-13 4.4075072307499365e-12 1.7854465924299572e-12 2788/10694/84617/9134/8841/54331/59345/1459/2770/2781/51807/8237/10575/10382/26224/10681/898/51764/1460/7277/94235/10381/7278/112714/2775/10517/7203/10576/908/55970/6774/1457/2792/26272/346562/2793/26270/6950/7846/113457/347733/2785/10376/55294/2783/26190/2784/10238/2782/7157/2786/2771/10574/6468/10564/10383/60/54461/84790/22948/26234/10693/2791/7280/84261/2773/2790/2787 68 Vaccinia_virus R-HSA-195258 RHO GTPase Effectors 168/3478 327/10654 9.117598976769292e-13 4.856874839548257e-12 1.9674818844607416e-12 85415/3831/26999/5170/5905/11130/84617/4688/25/5590/5903/1072/3984/64837/71/5579/4638/1495/1499/7531/5747/4690/1783/1058/4659/991/1856/10006/4627/51807/2316/7532/10971/10458/4771/10382/5578/9212/389/5594/3985/54763/6722/3798/1027/10627/388/1080/7533/2810/7277/348995/55920/79023/10381/57122/79980/30851/7278/6232/7534/94274/332/112714/1780/6242/5528/3688/5048/5501/10398/8655/4085/5289/5585/5216/81624/10094/10152/6279/6714/23279/79902/3796/1730/5519/1432/4637/699/7846/999/113457/89953/347733/5880/51466/22919/79784/9475/995/3895/10376/391/23002/11113/51143/998/4628/23028/695/1742/8976/5527/1855/2885/5580/7454/701/10097/9055/1857/23433/23191/7514/6093/23380/57120/9928/367/8826/147700/10499/29941/5518/3799/10383/103910/29984/5347/387/1729/60/5300/84790/114822/5217/6396/5600/10095/5058/801/3071/10109/5586/55746/4660/140735/7280/4629/5500/7529/5879/4221/5595/64130/5515/1778/5516 168 Vaccinia_virus R-HSA-4615885 SUMOylation of DNA replication proteins 38/3478 45/10654 9.333132551292038e-13 4.952639304038112e-12 2.0062753175392848e-12 23165/7150/5905/5903/55706/7175/9631/9212/51588/7153/348995/79023/6613/57122/23636/332/10762/23511/53371/6790/5111/23279/4927/9688/79902/9883/7341/8086/7329/23225/9972/6612/7155/8021/6396/129401/55746/8480 38 Vaccinia_virus R-HSA-351202 Metabolism of polyamines 46/3478 59/10654 1.017874256632105e-12 5.3807475016620815e-012 2.1796985889309438e-12 5718/5689/5684/1728/5720/5682/5700/122706/5707/5690/5717/9491/23198/143471/5706/5705/10197/10213/5709/5695/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/5710/5702/5719/5704/5716/6303/5694/5693/5721/5696/5691 46 Vaccinia_virus R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 107/3478 185/10654 1.1055147339134041e-12 5.821817134867166e-12 2.3583724361650767e-12 6158/6138/6144/2091/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/10557/6147/6159/6129/6217/8780/6230/6222/1454/6176/6152/6136/27043/6125/6224/6146/6154/51065/6141/6202/6123/51096/6232/6134/6169/6160/55272/6164/6155/6175/6218/6209/6193/6173/10200/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/23481/6192/51077/140801/6156/6235/6143/6181/6124/6207/10969/6139/705/6233/7311/6223/25873/83732/26168/11340/3921/6188/6189/26354/6135/6201/6161/1453/9045/6187/4691/23016/6168/6208/54512/6157/6137/6170/10813/200916/6122/6133/9188 107 Vaccinia_virus R-HSA-4570464 SUMOylation of RNA binding proteins 39/3478 47/10654 1.4323655542821734e-12 7.374818931898922e-12 2.9874812773719364e-12 1912/23165/5903/55706/7175/9631/8535/6045/80012/348995/79023/6613/57122/23636/3183/10762/23511/53371/3190/1911/23279/4927/9688/79902/9883/7341/84733/57332/8086/7329/23225/9972/8021/6396/648/129401/55746/8480/6015 39 Vaccinia_virus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 39/3478 47/10654 1.4323655542821734e-12 7.374818931898922e-12 2.9874812773719364e-12 4893/71/5604/283455/8844/3674/7094/5594/409/5908/7414/54518/673/22866/6714/5605/5037/10256/3717/2244/2335/3690/408/1445/5894/2266/8826/5906/2243/7450/60/4140/3845/3265/369/801/5245/7529/5595 39 Vaccinia_virus R-HSA-6802949 Signaling by RAS mutants 39/3478 47/10654 1.4323655542821734e-12 7.374818931898922e-12 2.9874812773719364e-12 4893/71/5604/283455/8844/3674/7094/5594/409/5908/7414/54518/673/22866/6714/5605/5037/10256/3717/2244/2335/3690/408/1445/5894/2266/8826/5906/2243/7450/60/4140/3845/3265/369/801/5245/7529/5595 39 Vaccinia_virus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 39/3478 47/10654 1.4323655542821734e-12 7.374818931898922e-12 2.9874812773719364e-12 4893/71/5604/283455/8844/3674/7094/5594/409/5908/7414/54518/673/22866/6714/5605/5037/10256/3717/2244/2335/3690/408/1445/5894/2266/8826/5906/2243/7450/60/4140/3845/3265/369/801/5245/7529/5595 39 Vaccinia_virus R-HSA-9649948 Signaling downstream of RAS mutants 39/3478 47/10654 1.4323655542821734e-12 7.374818931898922e-12 2.9874812773719364e-12 4893/71/5604/283455/8844/3674/7094/5594/409/5908/7414/54518/673/22866/6714/5605/5037/10256/3717/2244/2335/3690/408/1445/5894/2266/8826/5906/2243/7450/60/4140/3845/3265/369/801/5245/7529/5595 39 Vaccinia_virus R-HSA-977606 Regulation of Complement cascade 39/3478 47/10654 1.4323655542821734e-12 7.374818931898922e-12 2.9874812773719364e-12 727/629/5199/1991/722/930/27202/1378/3078/7448/1604/1361/717/966/712/710/81494/3075/716/715/1380/3426/721/975/1369/731/725/728/10878/10877/719/732/713/720/4179/714/5627/1370/718 39 Vaccinia_virus R-HSA-674695 RNA Polymerase II Pre-transcription Events 59/3478 84/10654 1.6467027834345846e-12 8.446975389099628e-12 3.4218034447198196e-12 6884/6875/2963/5434/5440/902/6830/5430/6874/5436/6878/404672/6749/5441/5438/5431/5435/4686/6872/4331/5433/8148/2966/6879/9150/2962/54457/5437/8812/83860/2965/905/2068/5439/2071/6873/6827/2968/1025/23168/6881/2967/51616/6880/6908/11198/904/6883/6829/51497/6882/138474/1022/5432/22916/8178/55840/6877/80349 59 Vaccinia_virus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 68/3478 102/10654 1.688508303887621e-12 8.566241761481153e-12 3.4701173162602732e-12 8454/7124/1147/5718/5689/8945/5684/8744/5720/7186/5682/5700/122706/5707/356/5690/9039/5717/9491/23198/6500/330/143471/5706/5705/10197/7316/10213/5709/5695/9020/5714/9861/5715/5711/7132/5701/5688/329/5687/23291/5685/5683/5698/5708/5692/5686/5713/5699/5710/8718/5702/9040/5719/5704/6233/5716/7311/7187/958/5694/5693/5721/8742/5696/5691/4791/7314 68 Vaccinia_virus R-HSA-5689603 UCH proteinases 68/3478 102/10654 1.688508303887621e-12 8.566241761481153e-12 3.4701173162602732e-12 5718/5689/5684/5720/3607/221937/5682/5700/122706/5707/51377/83444/4738/5690/5717/9491/23198/143471/5706/5705/10197/86/580/7316/10213/5709/5695/8314/5714/4092/9861/5715/5711/5701/5688/5687/7046/7347/5685/5683/5698/5708/5692/5686/5713/55777/5699/5710/8473/5702/9958/5719/5704/6233/5716/7048/7311/60/7040/7345/3054/5694/5693/5721/5696/5691/7314/7528 68 Vaccinia_virus R-HSA-9006936 Signaling by TGF-beta family members 68/3478 102/10654 1.688508303887621e-12 8.566241761481153e-12 3.4701173162602732e-12 4093/57154/5590/10272/892/7027/9765/11167/7321/51377/6497/10273/4738/5045/50855/4086/91851/23370/64750/50848/130399/7323/8239/54778/7316/1875/9611/5501/9612/1024/6667/5933/4092/4609/4089/22938/23327/867/8812/7046/4088/650/1874/142/905/3065/2280/9958/9040/4087/5499/657/6233/7514/7048/1025/1030/7311/56288/25937/387/7040/57530/904/5500/7314/4221/5054 68 Vaccinia_virus R-HSA-6798695 Neutrophil degranulation 229/3478 480/10654 1.7078496390316407e-12 8.632743613353366e-12 3.4970566945980196e-12 10450/2717/25801/10694/5718/1828/2512/3303/58485/9798/23352/1727/5689/2934/5777/3837/23412/10890/7276/64333/5806/4893/5036/8621/5284/5005/29099/9218/4790/3240/960/4332/10159/1938/1823/1511/5657/57826/1915/8635/5707/5315/2358/203068/3848/1650/5199/23197/823/3684/383/387921/1991/5594/6317/7520/54472/8836/5717/2919/3577/5908/55860/7414/1460/1378/2760/10533/1265/29108/23385/4318/3958/54509/963/79980/10577/1604/3579/2517/11240/2357/25852/10213/5709/10576/5695/8804/6278/2896/8895/966/5611/8655/84061/5834/1315/102/6279/932/2799/5768/1471/9588/29952/4069/5317/7415/3146/9861/3074/3417/5337/5870/410/3043/388698/4353/1432/411/5701/6793/226/197/140885/2171/3310/5476/1832/2821/8649/5683/929/5265/55832/5708/3320/55313/201294/5686/5713/3615/388697/2588/23593/2495/4311/391/3728/3614/80142/175/2444/51143/5702/4860/6386/4125/566/9961/5478/5719/10075/5878/2683/56729/728/8566/10487/5473/3326/5580/6709/55004/10097/1675/23191/6093/3916/3685/719/93100/47/8826/5906/81567/9522/302/10383/387/1729/3687/5049/6036/353376/4282/2219/3608/2720/7097/3304/3312/5660/230/2547/3071/10493/317/387263/10970/2990/3689/5663/2665/7879/1075/671/1654/967/114790/2519/6037/5879/28956/51316/2950/1778/718/30 229 Vaccinia_virus R-HSA-1650814 Collagen biosynthesis and modifying enzymes 50/3478 67/10654 2.0121749470483125e-12 1.0134044733316047e-11 4.105221997231581e-12 255631/1310/1286/871/1287/1282/1308/1294/85301/169044/7373/10491/283208/1299/91522/256076/1284/136227/1305/1277/1280/1289/1307/649/1300/1298/1301/84570/1281/1297/1290/1303/1295/1288/1306/1292/81578/50509/1293/57642/340267/1285/131873/80781/1278/5479/1296/1302/5034/1291 50 Vaccinia_virus R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 34/3478 39/10654 2.2992176308156866e-12 1.153774064739031e-11 4.673848196890774e-12 6118/80010/83990/5888/9156/5883/1763/7486/10111/675/5982/545/472/580/11073/116028/641/6119/3364/10524/4683/144715/5985/84126/1111/5984/672/5932/7156/5983/6117/5884/5810/83695 34 Vaccinia_virus R-HSA-195721 Signaling by WNT 168/3478 331/10654 3.4353987790341936e-12 1.7176993895170967e-11 6.958265435018906e-12 2788/8454/57154/5718/27123/9070/5689/27161/51176/8945/1173/5684/8295/857/5720/7472/54331/6662/7015/7090/6885/1487/5579/6597/5682/1499/59345/51701/864/1459/4772/5700/122706/5707/1856/207/1454/1452/5690/1212/5578/5532/57690/5717/5929/9491/5582/50855/23198/6500/10681/27327/409/51764/1460/94235/55737/143471/5706/7471/3708/5705/8395/10197/6657/192670/7534/64750/2775/8452/5530/5528/55366/7316/10213/5709/9978/5695/55970/7091/54361/89780/1457/5216/2792/5714/4609/9861/5715/5881/5519/5711/2932/5701/10524/5688/1387/2793/5687/1455/5685/5683/5698/5708/5880/5692/5686/5713/324/2033/54894/2785/5534/5699/2783/23002/8724/2784/8312/5710/2782/5702/192669/3065/7088/2786/5719/23112/208/57680/5704/6233/5527/1855/7474/5716/1857/7514/23072/7311/5518/1213/387/1211/7089/331/4343/5593/25776/3845/6659/5694/26523/801/5693/5721/2791/5696/6259/5691/7314/5879/4221/2790/5515/2787/5592/5516 168 Vaccinia_virus R-HSA-111885 Opioid Signalling 62/3478 91/10654 3.77938736061471e-12 1.882896221025674e-11 7.627464836075882e-12 2788/3838/5321/54331/59345/5567/2770/2781/5578/5532/5594/5568/5582/10681/51764/112/94235/114/3708/108/5573/2775/113/5173/5530/5528/55970/111/107/5443/2792/346562/5566/5519/4988/2793/5576/2785/5534/2783/2784/2782/2786/5499/2771/5577/5580/1385/5144/5518/196883/115/801/1020/2791/814/109/2773/2790/5515/2787/5516 62 Vaccinia_virus R-HSA-1538133 G0 and Early G1 26/3478 27/10654 3.983638619520727e-12 1.9775410351384255e-11 8.010863551045265e-12 1017/9134/4605/7027/7153/898/4149/286826/5934/1869/1875/993/890/983/5933/5111/4609/5928/91750/990/1874/3065/8900/55957/1859/132660 26 Vaccinia_virus R-HSA-113418 Formation of the Early Elongation Complex 30/3478 33/10654 4.204488651563033e-12 2.0649704902180146e-11 8.365033412777517e-12 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/4686/4331/5433/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/2967/6829/51497/1022/5432/22916 30 Vaccinia_virus R-HSA-163359 Glucagon signaling in metabolic regulation 30/3478 33/10654 4.204488651563033e-12 2.0649704902180146e-11 8.365033412777517e-12 2788/54331/59345/5567/5568/51764/112/94235/114/108/5573/113/55970/2778/111/107/5566/5576/2785/2783/2784/2782/2786/5577/196883/115/2791/109/2790/2787 30 Vaccinia_virus R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 30/3478 33/10654 4.204488651563033e-12 2.0649704902180146e-11 8.365033412777517e-12 2963/5434/5440/902/5430/5436/404672/5441/5438/5431/5435/4686/4331/5433/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/2967/6829/51497/1022/5432/22916 30 Vaccinia_virus R-HSA-114452 Activation of BH3-only proteins 28/3478 30/10654 4.6436068461576306e-12 2.2645758739184222e-11 9.173619158643502e-12 23368/27113/596/10018/7531/7027/572/7532/207/10971/7533/2810/7534/1869/8655/5366/10000/5534/7157/90427/8626/208/7161/5599/7159/637/140735/7529 28 Vaccinia_virus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 28/3478 30/10654 4.6436068461576306e-12 2.2645758739184222e-11 9.173619158643502e-12 11065/7319/7321/65264/7320/10477/92912/7326/8239/7316/7317/54926/55236/3093/7322/7347/29089/7328/7324/6233/7327/7311/55284/27338/7874/7332/997/7314 28 Vaccinia_virus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 23/3478 23/10654 6.25818772547289e-12 3.041259649045597e-11 1.231990418347941e-11 11065/246184/7321/991/8697/8881/7316/891/983/51433/119504/51529/7324/64682/29945/10393/6233/51434/7311/25906/29882/7314/996 23 Vaccinia_virus R-HSA-380108 Chemokine receptors bind chemokines 45/3478 59/10654 7.08456906735763e-12 3.430814041360251e-11 1.389795845749583e-11 729230/57007/10803/7852/6351/6374/1237/1230/2919/3577/3576/5196/6360/3579/2920/2826/2921/1236/6352/6376/3627/6346/10563/6370/58191/1524/10663/643/51554/10850/1233/6372/6366/5473/4283/6364/6363/6373/2833/6347/6357/56477/1232/1234/6387 45 Vaccinia_virus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 31/3478 35/10654 8.972695407017901e-12 4.33002896819505e-11 1.7540607562591384e-11 23165/5903/55706/7175/9631/7884/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/10189/10482/8086/1977/23225/9972/8021/6396/129401/55746/22916/8480 31 Vaccinia_virus R-HSA-375276 Peptide ligand-binding receptors 112/3478 201/10654 9.156187898900028e-12 4.403236194436298e-11 1.7837164291351298e-11 729230/57007/10316/10803/4889/9283/727/351/7852/8484/1909/117579/283869/4986/6351/2358/6752/6374/1237/5539/2852/84539/1230/5179/6753/4886/2919/3577/4987/51289/5368/6754/27202/8862/301/8811/3576/5196/6360/3827/5173/56923/3579/2832/2357/4985/2920/2826/2921/1236/6352/6751/6376/5443/186/3627/2831/6346/1906/5367/10563/5540/4988/6370/58191/5697/6755/1524/256933/10663/643/51554/10850/51083/624/4852/1233/6288/6372/6366/185/339403/2861/728/183/10022/5473/4283/6364/719/2847/6363/2359/6373/2833/6347/187/10874/6357/6750/56477/5660/2587/1325/1232/129521/1234/50865/4887/718/6387/623 112 Vaccinia_virus R-HSA-72766 Translation 150/3478 291/10654 1.1220084408139121e-11 5.3770992751808597e-11 2.178220721011893e-11 6158/51264/8669/6138/6144/5464/6203/6227/9349/4736/6206/6194/1965/6234/27335/6191/6166/6128/29093/51121/6132/1917/1938/6147/56945/6159/8666/6129/1915/6217/1936/6230/6222/1650/1983/6176/6152/6136/92399/79590/8668/64432/8667/6125/1937/7818/6224/6146/6154/51065/8662/6141/10480/6184/26986/6202/116540/6123/6232/6134/6169/6160/6164/6155/6748/63931/8661/6175/6218/9669/6209/1964/6193/6173/6210/6231/6229/11224/6205/6165/6130/6142/6167/7458/6204/64969/8663/6228/23521/54148/116832/23107/8894/7965/6192/5018/1981/140801/6156/79587/6235/6143/1973/6181/6124/6185/28973/6207/64978/51116/1977/6139/6745/90480/6233/1975/28957/64975/7311/6223/25873/8664/3646/51386/3921/6188/6189/10102/8665/6135/6201/1978/6161/9045/51649/6187/54998/64965/6168/6208/6157/6137/6170/7284/1974/200916/6122/6133/55037/1968 150 Vaccinia_virus R-HSA-397795 G-protein beta:gamma signalling 29/3478 32/10654 1.1790199762803545e-11 5.630836783269969e-11 2.2810077944008312e-11 2788/5170/54331/59345/207/9459/10681/51764/94235/55970/2792/146850/2793/23533/10000/5294/2785/2783/2784/2782/998/695/2786/208/387/5058/2791/2790/2787 29 Vaccinia_virus R-HSA-73762 RNA Polymerase I Transcription Initiation 38/3478 47/10654 1.3143614275132632e-11 6.255637722013297e-11 2.534109751725698e-11 5434/5440/902/9015/2648/2074/9112/9219/9014/404672/5931/54700/5441/51082/5435/4331/9013/7343/1108/2966/8850/5928/5437/57459/2965/54815/2068/3066/3065/2071/1107/2968/57504/2967/6908/53615/1022/10919 38 Vaccinia_virus R-HSA-8868773 rRNA processing in the nucleus and cytosol 109/3478 195/10654 1.3341786244815993e-11 6.328210256530874e-11 2.5635083159650052e-11 6158/6138/6144/2091/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/10557/6147/6159/6129/6217/55226/8780/6230/6222/1454/6176/6152/6136/27043/6125/4839/6224/6146/6154/51065/6141/6202/6123/51096/6232/6134/6169/6160/55272/6164/6155/6175/6218/6209/6193/6173/10200/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/23481/6192/51077/140801/6156/6235/6143/6181/6124/6207/10969/6139/705/6233/7311/6223/25873/83732/26168/11340/3921/6188/6189/26354/6135/6201/6161/1453/9045/6187/4691/23016/6168/6208/54512/6157/6137/6170/10813/200916/6122/6133/9188 109 Vaccinia_virus R-HSA-166520 Signaling by NTRKs 66/3478 101/10654 1.4212634454597017e-11 6.7182589486747e-11 2.721513980348557e-11 5295/627/1173/5800/4893/6464/5290/3667/5335/5899/5291/5604/2904/5045/5594/7074/10817/5528/673/6774/5046/6714/5605/5519/5898/5598/1432/2889/466/4914/2534/6195/4803/5603/6654/2885/1398/5900/8660/1385/6196/5906/1759/5518/1213/387/1211/8851/5296/581/6197/3845/5600/3265/1399/6300/1020/5781/51231/7529/1846/5879/5595/5515/5516/5607 66 Vaccinia_virus R-HSA-1236975 Antigen processing-Cross presentation 65/3478 99/10654 1.478888130905562e-11 6.966870956817018e-11 2.8222247539300558e-11 23643/1147/5718/5689/4688/5684/5720/5682/5700/122706/5707/5690/5717/9491/23198/811/143471/5706/5705/10333/10197/7099/8517/4615/7316/10213/5709/5695/7096/5714/9861/5715/5711/5701/5688/5687/5685/5683/929/5698/5708/5692/5686/5713/114609/5699/2923/5710/5702/695/5719/9902/5704/6233/5716/3685/7311/5694/7097/3551/5693/5721/5696/5691/7314 65 Vaccinia_virus R-HSA-68886 M Phase 192/3478 395/10654 1.4969111699866057e-11 7.027871086208301e-11 2.8469354276640887e-11 10844/4000/115106/5718/23165/4926/5689/5905/11130/22995/84617/5684/5903/5720/11065/55706/7175/5579/5682/22981/9631/246184/7531/10142/23383/1459/55869/1783/1058/5700/11190/122706/7321/5707/991/203068/51807/7532/1454/2801/8697/5690/10382/5578/9212/5594/5717/9491/23198/5925/1460/23244/7277/348995/143471/55920/79023/5706/9133/10381/5705/57122/23636/79980/10197/7278/6232/332/7443/112714/1780/10762/8881/23141/10051/5885/23511/5528/5048/7316/10213/5709/891/5695/5501/53371/26003/8655/4085/9738/1457/983/5714/4957/23279/4927/9688/51433/9861/79902/5566/3796/8615/5715/5519/5711/9883/5701/5688/699/5687/7846/113457/5685/7283/5683/7444/5698/347733/5708/3320/5692/22919/5686/5713/80097/119504/8243/9126/10376/5699/5710/51143/5702/10540/5520/51529/8086/7324/5719/64682/29945/10393/9232/5577/5704/6233/5527/9700/23133/51434/23225/80254/5716/701/7514/7311/54930/9972/5518/25906/10383/55835/5347/84790/8021/9493/29882/6396/129401/9662/5694/1453/64689/6418/5108/55746/8481/7112/5693/5721/140735/5696/7280/5691/8480/7314/996/5595/5515/1778/5516 192 Vaccinia_virus R-HSA-5619084 ABC transporter disorders 54/3478 77/10654 1.602314185033361e-11 7.497314683348666e-11 3.037103345031228e-11 5718/5689/5684/5720/5682/5700/122706/5707/10956/5690/5717/9491/23198/1080/143471/5706/5705/10197/7316/10213/5709/335/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/6400/5710/5702/5719/5704/6233/5716/7311/11160/5694/5693/5721/5696/5691/7314 54 Vaccinia_virus R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 35/3478 42/10654 1.6381627773416617e-11 7.613608881269131e-11 3.084213212020861e-11 6118/80010/83990/5888/9156/5883/1763/7486/10111/675/5982/545/472/580/11073/116028/641/6119/3364/10524/4683/144715/5985/84126/1111/5984/79728/672/5932/7156/5983/6117/5884/5810/83695 35 Vaccinia_virus R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 35/3478 42/10654 1.6381627773416617e-11 7.613608881269131e-11 3.084213212020861e-11 2788/10694/54331/59345/1459/2770/2781/10575/10681/51764/1460/94235/2775/7203/10576/908/55970/1457/2792/346562/2793/6950/2785/2783/2784/2782/2786/2771/10574/22948/10693/2791/2773/2790/2787 35 Vaccinia_virus R-HSA-392170 ADP signalling through P2Y purinoceptor 12 22/3478 22/10654 1.9252619183225576e-11 8.918019253768369e-11 3.612619617905028e-11 2788/54331/59345/64805/2770/10681/51764/94235/55970/2792/346562/2793/2785/2783/2784/2782/2786/2771/2791/2773/2790/2787 22 Vaccinia_virus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 36/3478 44/10654 2.3859636777431275e-11 1.1015198978914104e-10 4.46217066749855e-11 892/7027/7321/6497/64750/7323/8239/54778/7316/1875/9611/9612/1024/6667/5933/4092/4609/4089/22938/23327/8812/4088/1874/142/905/3065/4087/6233/1025/1030/7311/25937/904/7314/4221/5054 36 Vaccinia_virus R-HSA-159227 Transport of the SLBP independent Mature mRNA 30/3478 34/10654 2.452703082151058e-11 1.1248323737679522e-10 4.556607677889557e-11 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/10189/10482/8086/1977/23225/9972/8021/6396/129401/55746/22916/8480 30 Vaccinia_virus R-HSA-4085377 SUMOylation of SUMOylation proteins 30/3478 34/10654 2.452703082151058e-11 1.1248323737679522e-10 4.556607677889557e-11 23165/5903/55706/7175/9631/51588/348995/79023/6613/57122/23636/10762/23511/10210/53371/23279/4927/9688/79902/9883/7341/8086/7329/23225/9972/8021/6396/129401/55746/8480 30 Vaccinia_virus R-HSA-202040 G-protein activation 26/3478 28/10654 3.833666363181928e-11 1.7465881292786086e-10 7.075291452825374e-11 2788/54331/59345/2770/2781/10681/51764/94235/2775/5173/55970/5443/2792/346562/4988/2793/2785/2783/2784/2782/2786/2771/2791/2773/2790/2787 26 Vaccinia_virus R-HSA-69205 G1/S-Specific Transcription 26/3478 28/10654 3.833666363181928e-11 1.7465881292786086e-10 7.075291452825374e-11 8318/7027/898/286826/5934/5422/1869/1875/1876/983/5933/5111/4998/5928/91750/990/1874/81620/3065/8900/7298/55957/1719/7083/132660/6241 26 Vaccinia_virus R-HSA-5696400 Dual Incision in GG-NER 34/3478 41/10654 4.218854568364982e-11 1.9157749433395084e-10 7.760653960098483e-11 6118/5982/404672/54107/8450/7316/9978/5111/5426/1643/2966/6119/5427/1642/2965/5985/142/2068/2071/5984/6233/2067/51426/2968/7311/2967/5983/6117/5981/10714/5424/7314/8451/56655 34 Vaccinia_virus R-HSA-177243 Interactions of Rev with host cellular proteins 31/3478 36/10654 4.432625408148751e-11 2.0062699968254965e-10 8.127242320410334e-11 23165/5905/3837/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/5901/8086/23225/7514/9972/8021/6396/129401/1104/55746/8480 31 Vaccinia_virus R-HSA-416572 Sema4D induced cell migration and growth-cone collapse 21/3478 21/10654 5.92169799754811e-11 2.6715152203922257e-10 1.0822098517720359e-10 27289/3984/4627/389/3985/10627/388/2064/5364/10398/9826/4637/23365/79784/9475/4628/6093/10507/103910/387/4629 21 Vaccinia_virus R-HSA-5696395 Formation of Incision Complex in GG-NER 35/3478 43/10654 6.035212181176255e-11 2.713885997054907e-10 1.0993739209046289e-10 6118/902/404672/6613/7336/8450/54778/7316/9978/4331/1643/2966/6119/7341/1642/2965/142/2068/2071/7329/6233/2067/2968/7311/2967/6612/5887/6117/7334/1022/5886/7508/7314/8451/8554 35 Vaccinia_virus R-HSA-5685942 HDR through Homologous Recombination (HRR) 48/3478 67/10654 6.476816834749699e-11 2.9030392608829556e-10 1.1759984237511802e-10 6118/80010/83990/5888/9156/5883/1763/7486/10111/675/5982/54107/545/472/580/11073/7316/116028/641/5111/5426/6119/3364/10524/4683/5427/144715/5985/84126/1111/5984/79728/6233/51426/672/5932/7311/7156/5983/6117/5981/10714/5884/5810/5424/83695/7314/56655 48 Vaccinia_virus R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 29/3478 33/10654 6.678660531929638e-11 2.9742587899429414e-10 1.2048488960969697e-10 23165/3303/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/5901/8086/23225/7514/9972/8021/6396/129401/3304/55746/8480 29 Vaccinia_virus R-HSA-180746 Nuclear import of Rev protein 29/3478 33/10654 6.678660531929638e-11 2.9742587899429414e-10 1.2048488960969697e-10 23165/3837/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/5901/8086/23225/9972/8021/6396/129401/1104/55746/8480 29 Vaccinia_virus R-HSA-3899300 SUMOylation of transcription cofactors 36/3478 45/10654 8.175386175199261e-11 3.6218178014354453e-10 1.4671699701045732e-10 1912/1487/3622/8535/6045/51588/4869/80012/6613/10210/28996/1655/9612/1911/9994/7341/1387/84733/10521/1616/2033/57332/7329/115426/10155/10499/6612/9063/25942/6294/648/11315/8648/10891/6015/8554 36 Vaccinia_virus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 128/3478 244/10654 8.18504672815375e-11 3.6218178014354453e-10 1.4671699701045732e-10 10450/23165/22827/23451/7919/2963/6635/5434/5440/5903/6633/220988/6432/8683/6431/6430/6632/6627/55706/7175/24148/10946/9631/7884/27339/11051/5430/4904/5436/9879/6428/3184/25804/9589/55749/3178/23450/348995/79023/5441/57122/23636/3183/5438/10762/5431/9092/55110/5093/22794/23511/5435/10594/4686/6625/10713/53371/11338/1655/9343/3185/4116/3190/5433/6626/56339/24144/23279/4927/9688/79902/2962/22938/988/9883/10236/5437/4670/23020/10189/6631/10482/10949/55660/3181/5439/11193/1660/8086/2521/1977/3191/6638/57794/57721/9877/27316/6636/3187/23225/1993/1665/10286/9972/23524/6634/5094/51593/9775/8021/3192/6396/129401/3312/2733/6426/84991/5432/55746/22916/84324/56259/5725/8480/10992/55339/6628/1994 128 Vaccinia_virus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 27/3478 30/10654 9.180362495287012e-11 4.036445097134131e-10 1.635132233914111e-10 6118/7320/5982/54107/8450/7316/9978/5111/5426/6119/5427/1642/5985/7398/5984/57599/6233/7311/5983/6117/5981/10714/5424/7314/51514/8451/56655 27 Vaccinia_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 27/3478 30/10654 9.180362495287012e-11 4.036445097134131e-10 1.635132233914111e-10 7124/1147/7186/6885/8737/55072/7375/330/23118/27005/8517/7316/7128/7132/329/9099/10616/10454/6233/7311/331/8717/1540/3551/7185/7314/257397 27 Vaccinia_virus R-HSA-165159 mTOR signalling 33/3478 40/10654 1.081180998099159e-10 4.738720513820681e-10 1.9196184942933104e-10 5563/6194/389541/207/84335/51422/7249/58528/53632/6198/153129/64223/5571/10325/8649/6794/1981/6009/1977/208/10542/1975/2475/55004/5562/10670/1978/5564/5565/64121/57521/7529/28956 33 Vaccinia_virus R-HSA-72312 rRNA processing 111/3478 205/10654 1.2339377278835255e-10 5.391179031920135e-10 2.1839243199798076e-10 6158/6138/6144/2091/6203/6227/9349/4736/6206/6194/6234/6191/6166/6128/51121/6132/10557/6147/6159/6129/6217/3028/55226/8780/6230/6222/1454/6176/6152/6136/27043/6125/4839/6224/6146/6154/51065/6141/6202/6123/51096/6232/6134/6169/6160/55272/6164/6155/6175/6218/54931/6209/6193/6173/10200/6210/6231/6229/11224/6205/6165/6130/6142/6167/6204/6228/23521/116832/23481/6192/51077/140801/6156/6235/6143/6181/6124/6207/10969/6139/705/6233/7311/6223/25873/83732/26168/11340/3921/6188/6189/26354/6135/6201/6161/1453/9045/6187/4691/23016/6168/6208/54512/6157/6137/6170/10813/200916/6122/6133/9188 111 Vaccinia_virus R-HSA-5693532 DNA Double-Strand Break Repair 94/3478 166/10654 1.3149711750766555e-10 5.727154331701786e-10 2.3200252774440826e-10 8467/1017/6118/80010/25/3838/2237/5893/83990/151987/5888/9156/5883/322/1763/7486/10111/27343/51588/7520/51720/675/7515/5982/63967/54107/5531/51548/11200/545/472/6613/7336/3981/580/11073/5591/29086/7316/116028/890/8314/641/5111/5426/64421/9656/6119/3364/22976/7341/10524/4683/5427/144715/5985/165918/84126/142/1111/7157/8900/5984/7329/79728/8924/6233/2067/51426/672/2138/5932/7158/7311/6047/9025/79184/23030/5536/7156/5983/6117/5599/7334/5981/10714/2547/5884/5810/5424/83695/55183/7314/56655 94 Vaccinia_virus R-HSA-1442490 Collagen degradation 46/3478 64/10654 1.356819513892151e-10 5.890893500754323e-10 2.3863547299274587e-10 1310/1286/1287/1282/1308/1294/7373/1299/91522/256076/1284/1991/136227/5045/1305/4318/4312/1277/1280/1289/1307/1300/4313/1298/102/1301/84570/1281/1297/1290/1303/1295/1288/6868/1306/1292/50509/1293/1285/131873/80781/1278/1296/4323/1302/1291 46 Vaccinia_virus R-HSA-392518 Signal amplification 28/3478 32/10654 1.8111536492833061e-10 7.736599142444485e-10 3.134035601689463e-10 2788/5321/54331/59345/64805/2770/10681/51764/94235/55970/2767/2792/346562/6714/1432/2793/2785/2783/2784/2782/2776/2786/2771/2791/2773/2790/2787/10672 28 Vaccinia_virus R-HSA-5213460 RIPK1-mediated regulated necrosis 20/3478 20/10654 1.821033444358774e-10 7.736599142444485e-10 3.134035601689463e-10 11035/7186/8737/356/355/330/841/7316/8797/329/8837/197259/6233/7311/8772/331/8717/8743/8795/7314 20 Vaccinia_virus R-HSA-5218859 Regulated Necrosis 20/3478 20/10654 1.821033444358774e-10 7.736599142444485e-10 3.134035601689463e-10 11035/7186/8737/356/355/330/841/7316/8797/329/8837/197259/6233/7311/8772/331/8717/8743/8795/7314 20 Vaccinia_virus R-HSA-5625900 RHO GTPases activate CIT 20/3478 20/10654 1.821033444358774e-10 7.736599142444485e-10 3.134035601689463e-10 4659/4627/389/1027/10627/388/10398/4637/79784/11113/4628/1742/9055/9928/103910/387/4660/4629/5500/5879 20 Vaccinia_virus R-HSA-5627117 RHO GTPases Activate ROCKs 20/3478 20/10654 1.821033444358774e-10 7.736599142444485e-10 3.134035601689463e-10 1072/3984/4659/4627/389/3985/10627/388/10398/4637/79784/9475/4628/6093/103910/387/5058/4660/4629/5500 20 Vaccinia_virus R-HSA-8964616 G beta:gamma signalling through CDC42 20/3478 20/10654 1.821033444358774e-10 7.736599142444485e-10 3.134035601689463e-10 2788/54331/59345/9459/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/998/2786/5058/2791/2790/2787 20 Vaccinia_virus R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 20/3478 20/10654 1.821033444358774e-10 7.736599142444485e-10 3.134035601689463e-10 2648/23462/55534/3280/84441/10046/22938/8850/1387/4088/59/2033/4855/4853/9794/2324/23493/388585/3516/4851 20 Vaccinia_virus R-HSA-373076 Class A/1 (Rhodopsin-like receptors) 164/3478 335/10654 2.398298535848634e-10 1.015793110749345e-9 4.114898179968846e-10 729230/151/57007/10316/10803/4544/4543/4889/1880/9283/727/351/11251/7852/9294/3352/8484/1909/117579/283869/338442/4986/23566/6351/2358/64805/6752/6374/1237/5539/1903/2852/84539/1230/5179/3354/6753/2841/4886/2919/3577/4987/51289/5368/6754/27202/8862/301/8811/3576/56670/5196/6360/3827/150/5173/56923/3579/2832/2357/4985/27199/2920/2826/2921/1236/2853/6352/140/6751/6376/165140/27198/5443/6010/186/3627/53637/2840/2831/3361/6346/152/1906/5367/10563/134/5540/4988/1901/6370/58191/5030/5697/6755/1524/5733/256933/10663/1129/643/5729/51554/10850/51083/3355/624/3351/4852/1233/6288/6372/6366/185/1241/339403/2861/728/183/10022/5473/4283/6364/8843/719/2847/6363/2359/6373/57121/2833/6347/1268/9290/11255/9170/187/1132/10874/1814/6357/6750/8698/56477/5660/1815/2587/1325/53829/1232/9934/1902/3350/129521/154/1234/1269/59340/1813/50865/4887/718/6387/623 164 Vaccinia_virus R-HSA-933541 TRAF6 mediated IRF7 activation 26/3478 29/10654 2.548044734150687e-10 1.0759274258532627e-9 4.3584975715735434e-10 3443/3665/3441/7186/80143/29110/57506/3449/7706/3444/23586/1387/3451/3448/2033/64135/3440/3661/7189/10010/84282/3452/9641/3456/3446/3445 26 Vaccinia_virus R-HSA-166208 mTORC1-mediated signalling 22/3478 23/10654 3.0513011125378524e-10 1.2767528824365335e-9 5.172025736946018e-10 6194/389541/84335/58528/6198/153129/64223/10325/8649/1981/6009/1977/10542/1975/2475/55004/10670/1978/64121/57521/7529/28956 22 Vaccinia_virus R-HSA-166663 Initial triggering of complement 22/3478 23/10654 3.0513011125378524e-10 1.2767528824365335e-9 5.172025736946018e-10 5648/629/5199/10584/3004/10747/1401/717/712/716/715/78989/2220/721/1675/713/2219/720/8547/714/4153/718 22 Vaccinia_virus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 22/3478 23/10654 3.0513011125378524e-10 1.2767528824365335e-9 5.172025736946018e-10 5601/6885/10392/8767/23118/8517/7316/7335/64127/5602/3656/10454/3654/7189/5609/6233/7311/5599/7334/6416/7314/257397 22 Vaccinia_virus R-HSA-165054 Rev-mediated nuclear export of HIV RNA 29/3478 34/10654 3.1189213740645777e-10 1.3011162961082652e-9 5.270720013875776e-10 23165/5905/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/5901/8086/23225/7514/9972/8021/6396/129401/1104/55746/8480 29 Vaccinia_virus R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 37/3478 48/10654 3.1647113463011676e-10 1.312312938511113e-9 5.316076733622824e-10 2963/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/5435/4686/4331/5433/2966/9150/2962/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/2967/11198/904/6829/51497/1022/5432/22916/8178 37 Vaccinia_virus R-HSA-73893 DNA Damage Bypass 37/3478 48/10654 3.1647113463011676e-10 1.312312938511113e-9 5.316076733622824e-10 6118/7320/5982/54107/9636/7706/8450/7316/9978/11201/5111/5426/9100/7415/6119/51455/5427/1642/5985/25898/7398/5984/9246/57599/6233/51426/7311/7318/5983/6117/5981/10714/5424/7314/51514/8451/56655 37 Vaccinia_virus R-HSA-909733 Interferon alpha/beta signaling 48/3478 69/10654 3.385806531315425e-10 1.3998035957826459e-9 5.670494520631961e-10 3443/3665/5777/3441/10379/5770/9021/54739/4600/9636/2537/11274/8638/3449/3444/3663/8519/3434/6772/8651/3659/3433/6041/1958/25939/4939/6059/3451/3448/3440/3454/3661/4599/3716/10581/3452/4940/91543/3437/3456/6773/4938/7297/5781/3430/5696/3446/3445 48 Vaccinia_virus R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 27/3478 31/10654 4.890261368774098e-10 2.015777379688133e-9 8.165755982320158e-10 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/5901/8086/23225/7514/9972/8021/6396/129401/55746/8480 27 Vaccinia_virus R-HSA-75893 TNF signaling 34/3478 43/10654 4.975943967657909e-10 2.045009612820832e-9 8.284173464818571e-10 7124/1147/25999/7186/6885/8737/55072/7375/330/23118/841/27005/8517/8887/7316/8439/7128/7132/329/9099/10616/10454/8567/6868/6233/7311/8772/331/8717/1540/3551/7185/7314/257397 34 Vaccinia_virus R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 19/3478 19/10654 5.598927632482109e-10 2.2874674840671744e-9 9.26635127499756e-10 11065/246184/7321/991/8697/8881/51433/119504/51529/8556/7324/64682/29945/10393/51434/51343/25906/29882/996 19 Vaccinia_virus R-HSA-176412 Phosphorylation of the APC/C 19/3478 19/10654 5.598927632482109e-10 2.2874674840671744e-9 9.26635127499756e-10 11065/246184/7321/8697/8881/891/983/51433/119504/51529/7324/64682/29945/10393/51434/25906/5347/29882/996 19 Vaccinia_virus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 56/3478 86/10654 6.124308231820617e-10 2.494754970903398e-9 1.0106056617834022e-9 5295/26999/25/1072/3984/5290/5335/71/5291/5747/4690/10006/5336/4627/10458/4771/5594/4644/10451/3708/1793/6850/4620/10094/10152/4641/6714/5337/4650/4067/3320/2534/998/695/8976/2885/7525/1398/7410/3326/5580/7454/10097/7409/23191/9844/60/5296/5338/10095/5058/3071/10109/63916/5879/5595 56 Vaccinia_virus R-HSA-187037 Signaling by NTRK1 (TRKA) 53/3478 80/10654 6.865758009783378e-10 2.788584998108498e-9 1.129633900050792e-9 5295/1173/4893/6464/5290/3667/5335/5899/5291/5604/5594/5528/673/6774/6714/5605/5519/5898/5598/1432/2889/466/4914/6195/4803/5603/6654/2885/1398/5900/8660/1385/6196/5906/1759/5518/1213/387/1211/5296/6197/3845/5600/3265/1399/6300/51231/7529/1846/5595/5515/5516/5607 53 Vaccinia_virus R-HSA-9006931 Signaling by Nuclear Receptors 148/3478 299/10654 6.894299529290073e-10 2.7919897216569445e-9 1.1310131268426006e-9 5295/2788/5105/5170/27161/3725/2963/3838/596/5434/5440/5590/1839/4893/6464/8841/685/857/112724/5290/54331/1374/7090/79718/5241/347/2309/9687/5747/59345/5160/5430/2770/207/5436/10901/1903/2625/57690/5594/2069/6722/1027/3315/10681/27327/51764/94235/4318/5441/1381/5481/6720/192670/200845/5438/348/5431/5885/2100/5435/4313/1950/9611/865/55970/5469/2874/1655/2194/9612/5433/6667/2792/346562/6714/2099/4609/2962/7391/8850/8503/10524/1387/5437/2793/2171/6907/10000/3320/1382/2033/8243/2785/4846/9126/595/2783/4602/2784/8312/2782/5439/192669/3065/2066/861/23028/6256/2786/23112/2771/208/10498/3326/7514/1385/1025/2353/10499/23030/1386/6908/1956/5536/5296/4343/3845/904/1071/3276/3265/26523/801/29116/8202/5432/8648/3480/2791/2288/2773/10728/5595/2790/2787/7528/6387 148 Vaccinia_virus R-HSA-5689896 Ovarian tumor domain proteases 31/3478 38/10654 6.989635160593008e-10 2.822345392834203e-9 1.1433099710284096e-9 7321/8737/10392/8767/55611/57506/7706/8517/7316/79155/983/2099/79589/7415/23586/64127/7128/324/64135/5728/7157/7189/6233/7311/55593/84282/78990/7187/387/10318/7314 31 Vaccinia_virus R-HSA-2219528 PI3K/AKT Signaling in Cancer 63/3478 101/10654 7.379613076185818e-10 2.9711523577085345e-9 1.2035905047757162e-9 5295/1147/2308/5170/1839/685/5290/3667/2309/5291/842/3815/572/207/2069/4303/84335/1027/8074/7249/930/2064/6199/2100/1950/4233/1026/6714/2099/64223/8503/2932/2261/5159/2247/29851/3164/5880/10000/3084/145957/2534/391/5728/2264/2066/208/9542/2885/10718/2475/7409/8660/1385/3932/2931/1956/5296/5781/5156/5879/253260/4193 63 Vaccinia_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 28/3478 33/10654 8.213564187389251e-10 3.297329391169308e-9 1.3357222614427063e-9 1147/351/4790/6885/10392/8767/23118/8517/7316/7335/5970/4792/4793/3146/64127/3656/10454/6288/3654/7189/6285/6233/7311/7334/3551/4791/7314/257397 28 Vaccinia_virus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 23/3478 25/10654 8.903811244798733e-10 3.523365306870356e-9 1.4272876371361578e-9 11065/246184/7321/991/8697/8881/7316/4085/51433/119504/51529/7324/64682/29945/10393/6233/51434/701/7311/25906/29882/7314/996 23 Vaccinia_virus R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 23/3478 25/10654 8.903811244798733e-10 3.523365306870356e-9 1.4272876371361578e-9 10694/84617/51807/10575/10382/7277/10381/7278/112714/7203/10576/908/6950/7846/113457/347733/10376/10574/10383/84790/22948/10693/7280 23 Vaccinia_virus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 23/3478 25/10654 8.903811244798733e-10 3.523365306870356e-9 1.4272876371361578e-9 1147/2308/5170/2309/842/572/207/4303/84335/1027/7249/6199/1026/64223/2932/3164/10000/208/2475/1385/2931/253260/4193 23 Vaccinia_virus R-HSA-9006335 Signaling by Erythropoietin 23/3478 25/10654 8.903811244798733e-10 3.523365306870356e-9 1.4272876371361578e-9 5295/4893/6464/5290/5335/5291/5336/6776/2889/4067/23533/3717/5294/2057/6654/2885/2056/7409/8660/3845/6777/3265/1399 23 Vaccinia_virus R-HSA-937041 IKK complex recruitment mediated by RIP1 23/3478 25/10654 8.903811244798733e-10 3.523365306870356e-9 1.4272876371361578e-9 23643/1147/23098/11035/7321/8737/330/7099/8517/7323/7316/7335/7322/329/929/7189/6233/7311/353376/7334/3551/7314/148022 23 Vaccinia_virus R-HSA-2979096 NOTCH2 Activation and Transmission of Signal to the Nucleus 21/3478 22/10654 8.984685566128457e-10 3.545239176378323e-9 1.436148570024432e-9 142678/182/23385/7316/3714/54492/1272/102/5664/9148/4853/83464/6233/7311/57534/54567/55851/51107/5663/28514/7314 21 Vaccinia_virus R-HSA-191859 snRNP Assembly 39/3478 53/10654 1.130204820906505e-9 4.434373022536854e-9 1.7963297138606447e-9 23165/6635/5903/6633/6632/11218/55706/7175/6606/9631/25929/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/1207/79084/8086/6636/23225/9972/6634/10419/8021/6396/129401/55746/22916/8480/6628 39 Vaccinia_virus R-HSA-194441 Metabolism of non-coding RNA 39/3478 53/10654 1.130204820906505e-9 4.434373022536854e-9 1.7963297138606447e-9 23165/6635/5903/6633/6632/11218/55706/7175/6606/9631/25929/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/1207/79084/8086/6636/23225/9972/6634/10419/8021/6396/129401/55746/22916/8480/6628 39 Vaccinia_virus R-HSA-114604 GPVI-mediated activation cascade 29/3478 35/10654 1.2497477588800695e-9 4.889549847595752e-9 1.980718273812302e-9 5295/5170/5777/5590/5290/5291/3937/5336/388/10451/1277/6850/8503/146850/4067/23533/5880/5294/2534/391/998/7410/7409/3932/387/5296/5781/1278/5879 29 Vaccinia_virus R-HSA-3928663 EPHA-mediated growth cone collapse 26/3478 30/10654 1.3143099884193508e-9 5.113256556069665e-9 2.0713401059358783e-9 2042/4627/10627/10398/2041/2045/6714/4637/1943/4067/2044/2043/285220/79784/2534/9475/1946/4628/7525/1942/6093/103910/387/25791/4629/1969 26 Vaccinia_virus R-HSA-6804758 Regulation of TP53 Activity through Acetylation 26/3478 30/10654 1.3143099884193508e-9 5.113256556069665e-9 2.0713401059358783e-9 23774/64769/7862/3622/9219/207/5931/84289/1108/29117/5928/27154/57459/10000/54815/2033/7994/3066/3065/7157/1107/5371/208/5300/5608/53615 26 Vaccinia_virus R-HSA-438064 Post NMDA receptor activation events 53/3478 81/10654 1.358230208524145e-9 5.269324478448013e-9 2.134561996589619e-9 5923/5170/5563/84617/3838/4893/2904/5567/51807/10382/5594/5568/51422/7277/114/53632/10381/7278/5573/112714/107/6714/5566/5571/7846/5576/113457/347733/3084/10376/6195/4137/2066/1742/5577/88/1385/6196/5562/10383/84790/8874/6197/3845/3265/5564/801/5565/5924/814/7280/5879/5595 53 Vaccinia_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 44/3478 63/10654 1.5193152448777724e-9 5.877797804904231e-9 2.381049766303595e-9 1147/3665/170506/11035/5434/5440/6737/4790/1499/8737/29110/7520/23220/147945/5441/51082/8517/6778/4615/7098/5591/5435/7316/51428/5970/4792/4793/3428/1387/5437/2033/22954/1660/3661/6233/7311/197358/81030/171568/3551/2547/4791/7314/148022 44 Vaccinia_virus R-HSA-5654738 Signaling by FGFR2 49/3478 73/10654 1.5341239010497462e-9 5.918555997086068e-9 2.3975605901173282e-9 5295/2963/5434/5440/4893/6464/5290/5335/5430/5436/5594/8074/3178/10817/5441/54845/5438/5431/5435/4686/7316/673/3185/5433/6714/8569/2962/867/5437/4670/2247/5439/7072/6654/6233/2885/3187/7311/5518/3845/3265/5781/5432/22916/5725/7314/5595/5515/5516 49 Vaccinia_virus R-HSA-1912420 Pre-NOTCH Processing in Golgi 18/3478 18/10654 1.7211038814762902e-9 6.584886397360945e-9 2.667485806417164e-9 4242/487/5045/3955/10402/488/4854/5986/6484/5870/489/4855/6400/4853/2683/6487/4851/10959 18 Vaccinia_virus R-HSA-5675482 Regulation of necroptotic cell death 18/3478 18/10654 1.7211038814762902e-9 6.584886397360945e-9 2.667485806417164e-9 7186/8737/356/355/330/841/7316/8797/329/8837/6233/7311/8772/331/8717/8743/8795/7314 18 Vaccinia_virus R-HSA-8964315 G beta:gamma signalling through BTK 18/3478 18/10654 1.7211038814762902e-9 6.584886397360945e-9 2.667485806417164e-9 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/695/2786/2791/2790/2787 18 Vaccinia_virus R-HSA-167169 HIV Transcription Elongation 35/3478 46/10654 1.7896009533878435e-9 6.790677590252502e-9 2.7508502037655966e-9 2963/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/5435/4686/4331/5433/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/1025/2967/11198/904/6829/51497/1022/5432/22916/8178 35 Vaccinia_virus R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 35/3478 46/10654 1.7896009533878435e-9 6.790677590252502e-9 2.7508502037655966e-9 2963/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/5435/4686/4331/5433/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/1025/2967/11198/904/6829/51497/1022/5432/22916/8178 35 Vaccinia_virus R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 35/3478 46/10654 1.7896009533878435e-9 6.790677590252502e-9 2.7508502037655966e-9 2963/5434/5440/902/5430/5436/404672/6749/5441/5438/5431/5435/4686/4331/5433/2966/9150/2962/5437/2965/2068/5439/2071/6827/2968/1025/2967/11198/904/6829/51497/1022/5432/22916/8178 35 Vaccinia_virus R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 24/3478 27/10654 1.9396491067167493e-9 7.339928996728682e-9 2.9733476384240072e-9 23643/7186/1612/842/8737/356/355/841/7099/9500/8797/90249/836/929/8837/1613/1630/8772/353376/8717/26060/8743/8795/148022 24 Vaccinia_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 36/3478 48/10654 2.0703440722319135e-9 7.813151335262126e-9 3.16504629427681e-9 5295/5777/6464/5290/5291/3561/7534/6776/7316/3560/6850/3718/5566/8503/867/2889/4067/3558/3717/3636/2534/6654/6233/2885/7525/1398/3716/7409/7311/9846/5296/6777/1399/3559/5781/7314 36 Vaccinia_virus R-HSA-1251985 Nuclear signaling by ERBB4 27/3478 32/10654 2.1517443054024146e-9 8.054502332384715e-9 3.262815689273078e-9 1839/685/5241/2069/23118/51741/23385/348/6776/9611/10413/6714/2099/5664/3084/145957/2066/6868/3925/6285/9542/83464/10718/55851/51107/5663/6387 27 Vaccinia_virus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 27/3478 32/10654 2.1517443054024146e-9 8.054502332384715e-9 3.262815689273078e-9 892/7027/54778/7316/1875/1024/6667/5933/4092/4609/4089/22938/8812/4088/1874/905/3065/4087/6233/1025/1030/7311/25937/904/7314/4221/5054 27 Vaccinia_virus R-HSA-5656169 Termination of translesion DNA synthesis 27/3478 32/10654 2.1517443054024146e-9 8.054502332384715e-9 3.262815689273078e-9 6118/5982/54107/9636/7706/7316/11201/5111/5426/9100/6119/51455/5427/5985/5984/9246/6233/51426/7311/7318/5983/6117/5981/10714/5424/7314/56655 27 Vaccinia_virus R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 22/3478 24/10654 2.5239680911683834e-9 9.346780230663665e-9 3.786307325056989e-9 6118/2237/1763/5982/54107/3978/5557/5422/5111/5426/6119/5427/5985/5984/23649/5983/6117/5981/10714/5558/5424/56655 22 Vaccinia_virus R-HSA-5260271 Diseases of Immune System 22/3478 24/10654 2.5239680911683834e-9 9.346780230663665e-9 3.786307325056989e-9 23643/1147/81793/4790/10333/7099/8517/4615/7098/7100/5970/4792/7096/929/114609/695/51135/7187/7097/3551/4791/148022 22 Vaccinia_virus R-HSA-5602358 Diseases associated with the TLR signaling cascade 22/3478 24/10654 2.5239680911683834e-9 9.346780230663665e-9 3.786307325056989e-9 23643/1147/81793/4790/10333/7099/8517/4615/7098/7100/5970/4792/7096/929/114609/695/51135/7187/7097/3551/4791/148022 22 Vaccinia_virus R-HSA-982772 Growth hormone receptor signaling 22/3478 24/10654 2.5239680911683834e-9 9.346780230663665e-9 3.786307325056989e-9 5777/3667/5770/2690/9021/5594/6776/6774/6772/8651/4067/3717/5618/6868/2688/8660/1154/5617/8835/6777/2689/5595 22 Vaccinia_virus R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 20/3478 21/10654 2.6398306336438118e-9 9.749774473591144e-9 3.949557130476215e-9 7832/4849/4869/4850/9337/10769/25904/246175/4848/23019/28984/995/7157/55571/55835/5325/57472/85456/29883/1263 20 Vaccinia_virus R-HSA-400253 Circadian Clock 47/3478 70/10654 3.265654137787776e-9 1.202907175754274e-8 4.872882574022634e-9 8454/5187/8945/8841/1374/79718/5936/10135/1454/26224/6500/3091/200186/1408/6720/5465/406/7316/9611/5469/5501/8553/64784/1387/150094/2908/6907/1390/2033/6256/5499/10498/6233/1385/7311/10499/8864/1386/9575/23411/1453/23373/8648/5500/10891/7314/5054 47 Vaccinia_virus R-HSA-186763 Downstream signal transduction 25/3478 29/10654 3.5149394565950454e-9 1.2912973865740419e-8 5.230944381865585e-9 5295/4893/5290/5335/5291/4690/5921/6778/6776/6774/6772/6714/2889/5159/6654/2885/1398/5296/9564/3845/6777/3265/1399/5781/5156 25 Vaccinia_virus R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 33/3478 43/10654 3.5903759084130692e-9 1.31552133152172e-8 5.329073681938642e-9 2788/54331/59345/5567/5568/10681/51764/112/94235/114/108/5573/113/55970/2778/111/107/2792/5566/2793/5576/2785/2783/2784/2782/2786/5577/196883/115/2791/109/2790/2787 33 Vaccinia_virus R-HSA-8934593 Regulation of RUNX1 Expression and Activity 17/3478 17/10654 5.289622070864882e-9 1.9330149256326814e-8 7.83049177550613e-9 27161/894/57690/27327/192670/865/6714/1021/595/192669/861/896/5371/23112/4343/26523/5781 17 Vaccinia_virus R-HSA-6803529 FGFR2 alternative splicing 23/3478 26/10654 5.316696360215015e-9 1.937795910236262e-8 7.84985916896012e-9 2963/5434/5440/5430/5436/3178/5441/54845/5438/5431/5435/4686/3185/5433/2962/5437/4670/5439/7072/3187/5432/22916/5725 23 Vaccinia_virus R-HSA-6806834 Signaling by MET 51/3478 79/10654 5.570055915057304e-9 2.0248103523239807e-8 8.202347845629352e-9 5295/255631/3675/4893/6464/85301/5290/85440/5770/5747/10048/2060/5908/382/1277/1280/1289/3912/3688/7316/6774/4233/3915/1301/6714/3910/1281/1290/867/2889/9146/2335/3913/6654/6233/2885/1398/5867/7311/5906/57610/50509/3845/3265/1399/5781/1278/10254/1302/7314/5879 51 Vaccinia_virus R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 26/3478 31/10654 5.605786016437506e-9 2.03246430177119e-8 8.233353394216563e-9 23165/3837/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/8086/23225/9972/8021/6396/129401/55746/8480 26 Vaccinia_virus R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 42/3478 61/10654 7.076614646251665e-9 2.5590368890492313e-8 1.0366457623889342e-8 26999/25/1072/3984/71/5747/4690/10006/4627/10458/4771/5594/4644/10451/1793/6850/4620/10094/10152/4641/4650/3320/998/695/8976/2885/1398/7410/3326/7454/10097/7409/23191/9844/60/10095/5058/3071/10109/63916/5879/5595 42 Vaccinia_virus R-HSA-168276 NS1 Mediated Effects on Host Pathways 31/3478 40/10654 7.139220467448706e-9 2.574953215473036e-8 1.043093341324057e-8 3839/23165/3837/3838/5903/55706/7175/9631/348995/9636/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/3840/9883/8086/23225/9972/5610/8021/6396/129401/55746/8480 31 Vaccinia_virus R-HSA-1474290 Collagen formation 56/3478 90/10654 7.374310415202634e-9 2.6528363441702983e-8 1.0746431855920723e-8 255631/1310/1286/871/1287/1282/1308/1294/85301/169044/7373/10491/283208/1299/91522/256076/1284/136227/1305/4318/1277/1280/1289/1307/649/1300/1298/667/5339/1301/84570/4015/1281/1297/1290/1303/1295/1288/1306/1292/81578/50509/1293/57642/340267/1285/131873/80781/1278/5479/1296/977/1302/5034/1291/3655 56 Vaccinia_virus R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 19/3478 20/10654 7.737891720682506e-9 2.7550077206028975e-8 1.1160320084220744e-8 11065/246184/7321/991/8697/8881/4085/51433/119504/51529/7324/64682/29945/10393/51434/701/25906/29882/996 19 Vaccinia_virus R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 19/3478 20/10654 7.737891720682506e-9 2.7550077206028975e-8 1.1160320084220744e-8 11065/246184/7321/991/8697/8881/4085/51433/119504/51529/7324/64682/29945/10393/51434/701/25906/29882/996 19 Vaccinia_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 19/3478 20/10654 7.737891720682506e-9 2.7550077206028975e-8 1.1160320084220744e-8 1147/11035/7321/8737/330/8517/7098/7323/7316/7335/7322/329/7189/6233/7311/7334/3551/7314/148022 19 Vaccinia_virus R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 19/3478 20/10654 7.737891720682506e-9 2.7550077206028975e-8 1.1160320084220744e-8 23368/27113/55240/472/5366/84883/147923/1387/51499/94241/7157/8626/63970/7161/581/7159/637/665/27166 19 Vaccinia_virus R-HSA-5357905 Regulation of TNFR1 signaling 27/3478 33/10654 8.138489795388232e-9 2.890207273490436e-8 1.1708002863540966e-8 7124/1147/25999/7186/8737/55072/7375/330/841/27005/8517/8887/7316/7128/7132/329/9099/10616/8567/6233/7311/331/8717/1540/3551/7185/7314 27 Vaccinia_virus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 32/3478 42/10654 8.526161155287286e-9 3.012431938794105e-8 1.2203125391428902e-8 23165/5903/55706/7175/9631/7884/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/10189/10482/8086/1977/23225/9972/8021/6396/129401/55746/22916/8480/55339 32 Vaccinia_virus R-HSA-168253 Host Interactions with Influenza Factors 32/3478 42/10654 8.526161155287286e-9 3.012431938794105e-8 1.2203125391428902e-8 3839/23165/3837/3838/5903/55706/7175/9631/348995/9636/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/3840/9883/8086/23225/9972/5610/8021/7040/6396/129401/55746/8480 32 Vaccinia_virus R-HSA-163685 Integration of energy metabolism 64/3478 108/10654 1.0442685090866207e-8 3.680182913702213e-8 1.490813219079065e-8 2788/5563/54331/59345/2740/5567/2770/5578/5568/51422/10681/51764/112/94235/114/3708/4082/108/5573/150/113/5528/55970/2778/2194/111/107/2767/2792/152/5566/5519/2793/5576/6794/2785/2783/2784/2782/3630/2776/6514/2786/2771/5577/9370/7086/47/8826/5906/6888/2182/5518/773/196883/115/5565/2791/109/6513/2790/5515/2787/5516 64 Vaccinia_virus R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 28/3478 35/10654 1.0995290955931897e-8 3.865095932478598e-8 1.5657200319293884e-8 23165/5903/55706/7175/9631/348995/79023/9133/57122/23636/10762/23511/891/53371/983/23279/4927/9688/79902/9883/8086/23225/9972/8021/6396/129401/55746/8480 28 Vaccinia_virus R-HSA-418592 ADP signalling through P2Y purinoceptor 1 22/3478 25/10654 1.4503605846884159e-8 5.059822190915507e-8 2.0496942639239708e-8 2788/5321/54331/59345/10681/51764/94235/55970/2767/2792/6714/1432/2793/2785/2783/2784/2782/2776/2786/2791/2790/2787 22 Vaccinia_virus R-HSA-429947 Deadenylation of mRNA 22/3478 25/10654 1.4503605846884159e-8 5.059822190915507e-8 2.0496942639239708e-8 9924/5073/4849/4850/255967/26986/10605/9337/25904/246175/4848/23019/1981/1973/1977/1975/55571/9775/57472/85456/29883/1974 22 Vaccinia_virus R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 22/3478 25/10654 1.4503605846884159e-8 5.059822190915507e-8 2.0496942639239708e-8 6118/7515/5982/54107/3978/7316/5111/5426/6119/5427/5985/5984/6233/51426/7311/5983/6117/5981/10714/5424/7314/56655 22 Vaccinia_virus R-HSA-193639 p75NTR signals via NF-kB 16/3478 16/10654 1.6253899361600372e-8 5.627912653954129e-8 2.2798232525613154e-8 4804/4790/5584/8767/8878/4615/7316/5970/4792/4803/3654/7189/6233/7311/3551/7314 16 Vaccinia_virus R-HSA-1963640 GRB2 events in ERBB2 signaling 16/3478 16/10654 1.6253899361600372e-8 5.627912653954129e-8 2.2798232525613154e-8 1839/4893/685/2069/2064/1950/3084/145957/2066/6654/9542/2885/10718/1956/3845/3265 16 Vaccinia_virus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 16/3478 16/10654 1.6253899361600372e-8 5.627912653954129e-8 2.2798232525613154e-8 57154/5590/50855/23370/50848/7316/7046/2280/6233/7048/7311/56288/387/7040/57530/7314 16 Vaccinia_virus R-HSA-113510 E2F mediated regulation of DNA replication 20/3478 22/10654 2.0053451403953426e-8 6.926192068447755e-8 2.8057460554684805e-8 5000/23594/7027/5925/5557/5422/1869/891/983/84515/5519/4998/23595/5518/23649/5001/5558/4999/5515/5516 20 Vaccinia_virus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 31/3478 41/10654 2.010361081665269e-8 6.926244025140292e-8 2.805767102716911e-8 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/10189/10482/8086/1977/23225/9972/8021/6396/129401/55746/22916/8480/55339 31 Vaccinia_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 26/3478 32/10654 2.057330009758931e-8 7.01823168353724e-8 2.8430305812847033e-8 57154/51377/10273/4738/5045/64750/7316/5501/4092/4089/23327/867/7046/4088/2280/9958/9040/4087/5499/6233/7514/7048/7311/7040/5500/7314 26 Vaccinia_virus R-HSA-2871796 FCERI mediated MAPK activation 26/3478 32/10654 2.057330009758931e-8 7.01823168353724e-8 2.8430305812847033e-8 3725/5601/4893/6464/5335/3937/5336/5594/4214/10451/6850/4067/5602/5609/6654/2885/7410/7409/2353/3845/5599/3265/5058/6416/5879/5595 26 Vaccinia_virus R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 26/3478 32/10654 2.057330009758931e-8 7.01823168353724e-8 2.8430305812847033e-8 2788/54331/59345/5594/10681/409/51764/94235/55970/2767/2792/6714/2793/408/2785/2783/2784/2768/2782/2776/2786/2791/5595/2790/2787/10672 26 Vaccinia_virus R-HSA-69190 DNA strand elongation 26/3478 32/10654 2.057330009758931e-8 7.01823168353724e-8 2.8430305812847033e-8 4172/6118/2237/8318/1763/5982/4173/3978/5557/5422/4174/84515/5111/4171/6119/5985/4175/5984/23649/5983/6117/5981/10714/5558/5424/4176 26 Vaccinia_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 18/3478 19/10654 2.2622904009581762e-8 7.623533346294584e-8 3.088233534923058e-8 5295/4893/6464/5290/5335/7316/1950/867/3320/6654/6233/2885/7311/1956/3845/3265/11140/7314 18 Vaccinia_virus R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 18/3478 19/10654 2.2622904009581762e-8 7.623533346294584e-8 3.088233534923058e-8 7027/7153/4149/286826/5934/1869/1875/993/5933/5111/4609/5928/91750/990/1874/3065/55957/132660 18 Vaccinia_virus R-HSA-392851 Prostacyclin signalling through prostacyclin receptor 18/3478 19/10654 2.2622904009581762e-8 7.623533346294584e-8 3.088233534923058e-8 2788/54331/59345/10681/51764/94235/55970/2778/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 18 Vaccinia_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 18/3478 19/10654 2.2622904009581762e-8 7.623533346294584e-8 3.088233534923058e-8 5295/4893/6464/5290/5335/7316/1950/867/3320/6654/6233/2885/7311/1956/3845/3265/11140/7314 18 Vaccinia_virus R-HSA-6804760 Regulation of TP53 Activity through Methylation 18/3478 19/10654 2.2622904009581762e-8 7.623533346294584e-8 3.088233534923058e-8 133383/11200/472/79813/7316/4194/56950/2033/7157/91875/6233/7311/10419/133746/26013/10919/7314/4193 18 Vaccinia_virus R-HSA-1433557 Signaling by SCF-KIT 32/3478 43/10654 2.288480914619392e-8 7.693072977543345e-8 3.116403493848073e-8 5295/5777/4893/5290/3815/10019/5578/4318/6776/9306/6774/6772/6714/8651/8503/867/4067/3717/2534/1111/6654/2885/7525/7409/9846/3932/5296/3845/6777/3265/5781/5879 32 Vaccinia_virus R-HSA-354192 Integrin alphaIIb beta3 signaling 23/3478 27/10654 2.4734718067830318e-8 8.274778870518114e-8 3.352047986309066e-8 5170/6464/5770/5747/207/3674/7094/5908/54518/6850/6714/2244/2335/3690/1445/6654/2885/1398/2266/5906/2243/7450/9564 23 Vaccinia_virus R-HSA-9006921 Integrin signaling 23/3478 27/10654 2.4734718067830318e-8 8.274778870518114e-8 3.352047986309066e-8 5170/6464/5770/5747/207/3674/7094/5908/54518/6850/6714/2244/2335/3690/1445/6654/2885/1398/2266/5906/2243/7450/9564 23 Vaccinia_virus R-HSA-3928665 EPH-ephrin mediated repulsion of cells 36/3478 51/10654 3.056707990938398e-8 1.0201302572167909e-7 4.1324676199623746e-8 1173/71/2042/1212/7074/10451/23385/4318/4313/2041/102/2045/6714/5664/1943/4067/2044/2043/285220/2534/1946/1948/2048/83464/7525/1942/7410/1759/1213/1211/60/55851/51107/5663/1969/5879 36 Vaccinia_virus R-HSA-112382 Formation of RNA Pol II elongation complex 41/3478 61/10654 3.158277901288848e-8 1.0464628931303958e-7 4.239139061664457e-8 2963/5434/5440/902/6830/5430/5436/404672/6749/5441/5438/5431/5435/4686/4331/5433/2966/9150/2962/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/23168/2967/11198/904/6829/51497/1022/5432/22916/8178/55840/80349 41 Vaccinia_virus R-HSA-2022090 Assembly of collagen fibrils and other multimeric structures 41/3478 61/10654 3.158277901288848e-8 1.0464628931303958e-7 4.239139061664457e-8 255631/1286/1287/1282/1308/1294/85301/7373/1299/256076/1284/4318/1277/1280/1289/649/1300/1298/667/5339/1301/4015/1281/1297/1290/1303/1295/1288/1306/1292/50509/1293/1285/131873/80781/1278/1296/977/1302/1291/3655 41 Vaccinia_virus R-HSA-75955 RNA Polymerase II Transcription Elongation 41/3478 61/10654 3.158277901288848e-8 1.0464628931303958e-7 4.239139061664457e-8 2963/5434/5440/902/6830/5430/5436/404672/6749/5441/5438/5431/5435/4686/4331/5433/2966/9150/2962/5437/8812/2965/905/2068/5439/2071/6827/2968/1025/23168/2967/11198/904/6829/51497/1022/5432/22916/8178/55840/80349 41 Vaccinia_virus R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 38/3478 55/10654 3.2019386559002915e-8 1.0583973838715761e-7 4.287484747129394e-8 3303/84617/5241/1783/51807/10382/10294/55860/7277/10381/3337/7278/112714/1780/3305/8655/832/7846/113457/2908/347733/3320/10376/51143/3301/10540/3326/3306/367/10383/84790/3304/3312/140735/7280/2288/10728/1778 38 Vaccinia_virus R-HSA-176033 Interactions of Vpr with host cellular proteins 28/3478 36/10654 3.40229109887811e-8 1.1219459933205196e-7 4.544915177198077e-8 23165/5903/55706/7175/9631/3159/348995/79023/57122/23636/10762/23511/53371/292/23279/4927/9688/79902/9883/8086/23225/9972/8021/6396/129401/55746/8480/291 28 Vaccinia_virus R-HSA-69473 G2/M DNA damage checkpoint 57/3478 95/10654 3.572587084722129e-8 1.1753047772779451e-7 4.761067423820214e-8 6118/80010/83990/9156/5883/1763/7531/7486/10111/7532/10971/51588/51720/5982/7533/2810/11200/545/472/7336/7534/580/11073/29086/891/116028/983/641/9656/6119/3364/7341/10524/4683/144715/5985/995/165918/84126/1111/7157/5984/8924/672/5932/7158/9025/79184/7156/5983/6117/7334/7465/5884/5810/83695/7529 57 Vaccinia_virus R-HSA-203927 MicroRNA (miRNA) biogenesis 21/3478 24/10654 3.9360401224884874e-8 1.2882569418492515e-7 5.218627778876314e-8 27161/5434/5440/5430/5436/5441/192670/5438/5431/5435/54487/5433/5437/57510/5439/192669/5901/29102/26523/5432/23405 21 Vaccinia_virus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 21/3478 24/10654 3.9360401224884874e-8 1.2882569418492515e-7 5.218627778876314e-8 6885/5606/10392/8767/23118/8517/7316/7335/64127/1432/3656/10454/3654/7189/6233/7311/5600/7334/5608/7314/257397 21 Vaccinia_virus R-HSA-5693538 Homology Directed Repair 76/3478 138/10654 3.943833525950055e-8 1.2882569418492515e-7 5.218627778876314e-8 1017/6118/80010/25/2237/5893/83990/151987/5888/9156/5883/1763/7486/10111/51588/51720/675/7515/5982/63967/54107/5531/51548/545/472/6613/7336/580/11073/29086/7316/116028/890/641/5111/5426/9656/6119/3364/7341/10524/4683/5427/144715/5985/165918/84126/142/1111/8900/5984/7329/79728/8924/6233/2067/51426/672/5932/7158/7311/6047/9025/79184/7156/5983/6117/7334/5981/10714/5884/5810/5424/83695/7314/56655 76 Vaccinia_virus R-HSA-2691230 Signaling by NOTCH1 HD Domain Mutants in Cancer 15/3478 15/10654 4.993509538205777e-8 1.615890352900701e-7 6.545845016880666e-8 142678/182/7316/3714/54492/102/9148/6868/6233/7311/57534/54567/4851/28514/7314 15 Vaccinia_virus R-HSA-2691232 Constitutive Signaling by NOTCH1 HD Domain Mutants 15/3478 15/10654 4.993509538205777e-8 1.615890352900701e-7 6.545845016880666e-8 142678/182/7316/3714/54492/102/9148/6868/6233/7311/57534/54567/4851/28514/7314 15 Vaccinia_virus R-HSA-354194 GRB2:SOS provides linkage to MAPK signaling for Integrins 15/3478 15/10654 4.993509538205777e-8 1.615890352900701e-7 6.545845016880666e-8 5747/3674/7094/5908/54518/6714/2244/2335/3690/6654/2885/2266/5906/2243/7450 15 Vaccinia_virus R-HSA-372708 p130Cas linkage to MAPK signaling for integrins 15/3478 15/10654 4.993509538205777e-8 1.615890352900701e-7 6.545845016880666e-8 5747/3674/7094/5908/54518/6714/2244/2335/3690/1398/2266/5906/2243/7450/9564 15 Vaccinia_virus R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 25/3478 31/10654 5.1652673385124246e-8 1.6636965729859785e-7 6.739504262979492e-8 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/8086/23225/9972/8021/6396/129401/55746/8480 25 Vaccinia_virus R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 25/3478 31/10654 5.1652673385124246e-8 1.6636965729859785e-7 6.739504262979492e-8 23165/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/8086/23225/9972/8021/6396/129401/55746/8480 25 Vaccinia_virus R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 31/3478 42/10654 5.273096895322809e-8 1.690564629634743e-7 6.84834465206398e-8 2788/54331/59345/2740/5567/5568/10681/51764/112/94235/114/3708/5573/55970/2778/111/2792/5566/2793/5576/2785/2783/2784/2782/2786/5577/8826/5906/2791/2790/2787 31 Vaccinia_virus R-HSA-3928662 EPHB-mediated forward signaling 31/3478 42/10654 5.273096895322809e-8 1.690564629634743e-7 6.84834465206398e-8 64283/1072/3984/71/2904/5747/3985/7074/5921/6383/6453/10094/6714/4067/2534/9475/998/1948/2048/8976/7525/10097/6093/8997/387/60/10095/3265/5058/10109/5879 31 Vaccinia_virus R-HSA-5693607 Processing of DNA double-strand break ends 58/3478 98/10654 5.4192008126677916e-8 1.733393331534617e-7 7.021840362591304e-8 1017/6118/80010/83990/151987/9156/5883/1763/7486/10111/51588/51720/5982/63967/5531/51548/545/472/6613/7336/580/11073/29086/7316/116028/890/641/9656/6119/3364/7341/10524/4683/144715/5985/165918/84126/1111/8900/5984/7329/8924/6233/672/5932/7158/7311/6047/9025/79184/7156/5983/6117/7334/5884/5810/83695/7314 58 Vaccinia_virus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 19/3478 21/10654 5.6169472047550315e-8 1.792505041148783e-7 7.261297259603278e-8 1147/11035/4790/8737/29110/23220/147945/8517/4615/7098/5970/4792/4793/1660/3661/81030/3551/4791/148022 19 Vaccinia_virus R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 73/3478 132/10654 5.7832500033630595e-8 1.8413336217604226e-7 7.459098007967359e-8 1017/6118/80010/25/5893/83990/151987/5888/9156/5883/1763/7486/10111/51588/51720/675/5982/63967/54107/5531/51548/545/472/6613/7336/580/11073/29086/7316/116028/890/641/5111/5426/9656/6119/3364/7341/10524/4683/5427/144715/5985/165918/84126/1111/8900/5984/7329/79728/8924/6233/2067/51426/672/5932/7158/7311/6047/9025/79184/7156/5983/6117/7334/5981/10714/5884/5810/5424/83695/7314/56655 73 Vaccinia_virus R-HSA-4086398 Ca2+ pathway 41/3478 62/10654 6.390426085630536e-8 2.029986268027131e-7 8.223315073976522e-8 2788/27161/51176/54331/6885/1499/59345/51701/4772/5578/5532/57690/10681/27327/51764/94235/3708/192670/2775/5530/55970/2792/2793/2785/5534/2783/2784/2782/192669/2786/23112/7474/4343/5593/3845/26523/801/2791/2790/2787/5592 41 Vaccinia_virus R-HSA-912694 Regulation of IFNA signaling 22/3478 26/10654 6.50316080235644e-8 2.061070414476812e-7 8.349234511998031e-8 3443/5777/3441/5770/9021/11274/3449/3444/6772/8651/3451/3448/3440/3454/3716/3452/3456/6773/7297/5781/3446/3445 22 Vaccinia_virus R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 17/3478 18/10654 6.595443129047066e-8 2.0807947001663295e-7 8.429136045515133e-8 7027/25946/2810/5934/891/983/6790/5933/5111/1647/2033/995/1874/7157/10498/581/3276 17 Vaccinia_virus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 17/3478 18/10654 6.595443129047066e-8 2.0807947001663295e-7 8.429136045515133e-8 23643/3665/23098/29110/7099/7316/929/3661/6233/10010/7311/7187/9641/353376/5781/7314/148022 17 Vaccinia_virus R-HSA-180910 Vpr-mediated nuclear import of PICs 26/3478 33/10654 6.675973836290764e-8 2.1014144916506156e-7 8.512665202734396e-8 23165/5903/55706/7175/9631/3159/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/8086/23225/9972/8021/6396/129401/55746/8480 26 Vaccinia_virus R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 23/3478 28/10654 9.550132003544927e-8 2.9993044954443816e-7 1.2149947148560559e-7 2788/54331/59345/2770/10681/51764/112/94235/150/55970/111/2792/152/2793/2785/2783/2784/2782/2786/2771/2791/2790/2787 23 Vaccinia_virus R-HSA-4551638 SUMOylation of chromatin organization proteins 45/3478 71/10654 9.941210712851797e-8 3.1080308887809797e-7 1.2590389235951069e-7 1912/23165/5903/55706/7175/9631/8535/6045/80012/348995/79023/6613/57122/23636/10762/23511/53371/9759/1911/23279/4927/9688/79902/9883/7341/84733/23512/57332/3066/3065/1107/8086/7329/23225/9972/6612/9063/8021/6396/648/129401/55746/8480/6015/8554 45 Vaccinia_virus R-HSA-70171 Glycolysis 45/3478 71/10654 9.941210712851797e-8 3.1080308887809797e-7 1.2590389235951069e-7 23165/7167/5903/2597/55706/7175/9631/5315/5567/5568/348995/79023/57122/23636/5214/10762/23511/5528/53371/5230/3098/23279/4927/9688/79902/5566/5519/9883/2023/226/2821/8086/23225/9972/5518/8021/6396/129401/2026/230/55746/2027/8480/5515/5516 45 Vaccinia_virus R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 20/3478 23/10654 1.0621964587775713e-7 3.3059372930492945e-7 1.3392092549460566e-7 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/9150/2962/5437/5439/6827/6829/51497/5432/22916 20 Vaccinia_virus R-HSA-428930 Thromboxane signalling through TP receptor 20/3478 23/10654 1.0621964587775713e-7 3.3059372930492945e-7 1.3392092549460566e-7 2788/54331/59345/10681/51764/94235/55970/2767/2792/2793/2785/2783/2784/2782/2776/2786/2791/2790/2787/10672 20 Vaccinia_virus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 29/3478 39/10654 1.0923590066336081e-7 3.377047375418632e-7 1.3680153912963183e-7 6118/5982/54107/9636/7706/7316/11201/5111/5426/9100/7415/6119/51455/5427/5985/25898/5984/9246/6233/51426/7311/7318/5983/6117/5981/10714/5424/7314/56655 29 Vaccinia_virus R-HSA-977444 GABA B receptor activation 29/3478 39/10654 1.0923590066336081e-7 3.377047375418632e-7 1.3680153912963183e-7 2788/54331/2770/2550/112/94235/114/108/113/55970/111/107/9568/2792/346562/2793/2785/2783/2784/2782/2786/2771/196883/3759/115/109/2773/2790/2787 29 Vaccinia_virus R-HSA-991365 Activation of GABAB receptors 29/3478 39/10654 1.0923590066336081e-7 3.377047375418632e-7 1.3680153912963183e-7 2788/54331/2770/2550/112/94235/114/108/113/55970/111/107/9568/2792/346562/2793/2785/2783/2784/2782/2786/2771/196883/3759/115/109/2773/2790/2787 29 Vaccinia_virus R-HSA-373755 Semaphorin interactions 42/3478 65/10654 1.1924646950313205e-7 3.678315373314875e-7 1.4900566931231835e-7 1400/27289/23396/23129/1072/3984/4627/2909/7094/389/3985/10627/388/1809/10371/2064/5364/3688/3672/10398/4233/9826/2932/4637/23365/3320/79784/2534/9475/1808/4628/3326/6093/10507/103910/387/8851/5058/6237/1020/4629/5879 42 Vaccinia_virus R-HSA-1250347 SHC1 events in ERBB4 signaling 14/3478 14/10654 1.533803160696004e-7 4.6382475492663003e-7 1.8789176847873368e-7 1839/4893/6464/685/2069/3084/145957/2066/6654/9542/2885/10718/3845/3265 14 Vaccinia_virus R-HSA-166786 Creation of C4 and C2 activators 14/3478 14/10654 1.533803160696004e-7 4.6382475492663003e-7 1.8789176847873368e-7 5648/10584/10747/1401/712/716/715/78989/2220/713/2219/8547/714/4153 14 Vaccinia_virus R-HSA-198323 AKT phosphorylates targets in the cytosol 14/3478 14/10654 1.533803160696004e-7 4.6382475492663003e-7 1.8789176847873368e-7 1147/842/572/207/84335/1027/7249/1026/2932/10000/208/2931/23608/4193 14 Vaccinia_virus R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 14/3478 14/10654 1.533803160696004e-7 4.6382475492663003e-7 1.8789176847873368e-7 1017/9134/1820/57060/25946/1027/898/1869/890/1026/7157/8900/144455/79733 14 Vaccinia_virus R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 14/3478 14/10654 1.533803160696004e-7 4.6382475492663003e-7 1.8789176847873368e-7 23368/25946/5457/207/54971/10848/5458/10000/7157/8626/208/7161/7159/51230 14 Vaccinia_virus R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 14/3478 14/10654 1.533803160696004e-7 4.6382475492663003e-7 1.8789176847873368e-7 4893/2909/5921/1793/5753/1398/9844/387/9564/3845/3265/63916/5829/5879 14 Vaccinia_virus R-HSA-8941856 RUNX3 regulates NOTCH signaling 14/3478 14/10654 1.533803160696004e-7 4.6382475492663003e-7 1.8789176847873368e-7 2648/864/55534/3280/182/84441/10046/22938/8850/1387/2033/9794/3516/4851 14 Vaccinia_virus R-HSA-9027284 Erythropoietin activates RAS 14/3478 14/10654 1.533803160696004e-7 4.6382475492663003e-7 1.8789176847873368e-7 4893/6464/2889/4067/3717/2057/6654/2885/2056/7409/8660/3845/3265/1399 14 Vaccinia_virus R-HSA-918233 TRAF3-dependent IRF activation pathway 14/3478 14/10654 1.533803160696004e-7 4.6382475492663003e-7 1.8789176847873368e-7 3665/80143/29110/57506/7706/23586/1387/2033/64135/3661/84282/7187/9641/3456 14 Vaccinia_virus R-HSA-3232118 SUMOylation of transcription factors 18/3478 20/10654 1.565880146096747e-7 4.714660874660858e-7 1.9098721232713184e-7 7020/6670/7021/1029/9112/51588/3090/6613/7341/7022/7157/7329/7158/6612/9063/4286/4193/8554 18 Vaccinia_virus R-HSA-69186 Lagging Strand Synthesis 18/3478 20/10654 1.565880146096747e-7 4.714660874660858e-7 1.9098721232713184e-7 6118/2237/1763/5982/3978/5557/5422/5111/6119/5985/5984/23649/5983/6117/5981/10714/5558/5424 18 Vaccinia_virus R-HSA-190236 Signaling by FGFR 52/3478 87/10654 1.6833813762379368e-7 5.057447301712673e-7 2.048732214944218e-7 5295/2963/5434/5440/4893/6464/5290/5335/5430/5436/5594/8074/3178/10817/5441/54845/5438/5431/5435/4686/7316/673/3185/5433/6714/8569/2962/2261/867/5437/4670/2247/2264/5439/7072/6654/6233/2885/3187/7311/5518/3845/3265/5781/5432/22916/2591/5725/7314/5595/5515/5516 52 Vaccinia_virus R-HSA-1643713 Signaling by EGFR in Cancer 21/3478 25/10654 1.6985857695938926e-7 5.070132092430046e-7 2.0538707241232866e-7 5295/1839/4893/6464/685/5290/5335/2069/7316/1950/867/3320/6654/6233/2885/7311/1956/3845/3265/11140/7314 21 Vaccinia_virus R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 21/3478 25/10654 1.6985857695938926e-7 5.070132092430046e-7 2.0538707241232866e-7 1017/994/902/2305/9133/891/993/890/4331/983/5519/995/5520/8900/7514/5518/5347/7465/1022/5515/5516 21 Vaccinia_virus R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 21/3478 25/10654 1.6985857695938926e-7 5.070132092430046e-7 2.0538707241232866e-7 23129/2648/23462/55534/3280/84441/10046/4854/6772/10320/22938/8850/1387/2173/26508/2033/9794/23493/388585/3516/4851 21 Vaccinia_virus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 45/3478 72/10654 1.8160411229020847e-7 5.409068720901908e-7 2.191171292601723e-7 5563/84617/10890/71/7531/11127/4627/51807/7532/207/10971/10382/51422/7533/2810/4644/7277/53632/10381/7278/7534/112714/4641/5898/5571/7846/113457/347733/10376/9847/208/5867/9882/23433/10383/60/84790/5564/801/5565/7280/7529/5879/55770/23265 45 Vaccinia_virus R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 16/3478 17/10654 1.916823360133691e-7 5.672650328600774e-7 2.2979461334936064e-7 23643/7186/8737/356/355/841/7099/8797/929/8837/8772/353376/8717/8743/8795/148022 16 Vaccinia_virus R-HSA-164378 PKA activation in glucagon signalling 16/3478 17/10654 1.916823360133691e-7 5.672650328600774e-7 2.2979461334936064e-7 5567/5568/112/114/108/5573/113/2778/111/107/5566/5576/5577/196883/115/109 16 Vaccinia_virus R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 16/3478 17/10654 1.916823360133691e-7 5.672650328600774e-7 2.2979461334936064e-7 23643/23098/6885/23118/7099/7316/929/3656/10454/7189/6233/7311/353376/7314/148022/257397 16 Vaccinia_virus R-HSA-187687 Signalling to ERKs 26/3478 34/10654 1.953569632651556e-7 5.769070237147985e-7 2.3370050818163602e-7 4893/6464/5899/5604/5594/673/6714/5605/5898/1432/2889/4914/4803/5603/6654/2885/1398/5900/5906/3845/5600/3265/1399/6300/7529/5595 26 Vaccinia_virus R-HSA-382556 ABC-family proteins mediated transport 59/3478 103/10654 2.082933639406091e-7 6.138006575696671e-7 2.4864582974321313e-7 5718/5689/5684/5720/1965/5682/5700/122706/5707/10956/5243/5690/5717/9491/23198/1080/143471/5706/5705/10197/5824/7316/10213/5709/335/5695/5714/7415/9861/5715/5711/5701/5688/5687/5685/8894/5683/5698/5708/5692/5686/5713/5699/6400/5710/5702/5719/5704/6233/5716/7311/11160/5694/5693/5721/5696/5691/7314/1968 59 Vaccinia_virus R-HSA-72163 mRNA Splicing - Major Pathway 93/3478 183/10654 2.2172613830589404e-7 6.519972432137224e-7 2.641189668500202e-7 10450/22827/23451/2963/6635/5434/5440/6633/220988/6432/8683/6431/6430/6632/6627/24148/10946/27339/11051/5430/4904/5436/9879/6428/3184/25804/55749/3178/23450/5441/3183/5438/5431/9092/55110/5093/22794/5435/10594/4686/6625/10713/11338/1655/9343/3185/4116/3190/5433/6626/24144/2962/22938/988/10236/5437/4670/23020/10189/6631/10949/55660/3181/5439/11193/1660/2521/3191/6638/57794/27316/6636/3187/1993/1665/10286/23524/6634/5094/51593/9775/3192/3312/6426/84991/5432/22916/56259/5725/10992/55339/6628/1994 93 Vaccinia_virus R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 28/3478 38/10654 2.515156502563455e-7 7.380279144174544e-7 2.98969316651722e-7 1912/6595/6597/1459/8535/6045/80012/1460/6598/6599/86/865/28996/1457/1911/6603/84733/8289/2033/6602/57332/861/648/6601/23466/23429/55193/6015 28 Vaccinia_virus R-HSA-1250196 SHC1 events in ERBB2 signaling 19/3478 22/10654 2.8490426945699793e-7 8.324734455652789e-7 3.372284601833886e-7 1839/4893/6464/685/5578/2069/2064/1950/3084/145957/2066/6654/9542/2885/10718/5580/1956/3845/3265 19 Vaccinia_virus R-HSA-912631 Regulation of signaling by CBL 19/3478 22/10654 2.8490426945699793e-7 8.324734455652789e-7 3.372284601833886e-7 5295/5290/5291/7316/6850/8503/867/2889/4067/2534/6233/2885/7525/1398/7409/7311/5296/1399/7314 19 Vaccinia_virus R-HSA-2980766 Nuclear Envelope Breakdown 35/3478 52/10654 3.072568881080025e-7 8.958964000622811e-7 3.629206013552694e-7 4000/23165/5903/55706/7175/5579/9631/5578/348995/79023/9133/57122/23636/7443/10762/23511/891/53371/983/23279/4927/9688/79902/9883/7444/8086/23225/9972/5347/8021/6396/129401/55746/7112/8480 35 Vaccinia_virus R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK 23/3478 29/10654 3.1836794397475304e-7 9.205419674426575e-7 3.7290432730149077e-7 5563/389541/51422/7249/58528/53632/153129/64223/5571/10325/8649/6794/6009/10542/2475/55004/5562/10670/5564/5565/64121/57521/28956 23 Vaccinia_virus R-HSA-8863795 Downregulation of ERBB2 signaling 23/3478 29/10654 3.1836794397475304e-7 9.205419674426575e-7 3.7290432730149077e-7 1839/8065/685/10273/207/10193/2069/2064/7316/1950/10000/3320/3084/145957/2066/208/9542/6233/10718/7311/1956/11140/7314 23 Vaccinia_virus R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 23/3478 29/10654 3.1836794397475304e-7 9.205419674426575e-7 3.7290432730149077e-7 5105/2308/2309/4303/23410/4287/6720/3484/114907/5443/84676/4089/4088/2908/4852/3630/3066/3065/6648/4087/56729/25942/10891 23 Vaccinia_virus R-HSA-9619483 Activation of AMPK downstream of NMDARs 23/3478 29/10654 3.1836794397475304e-7 9.205419674426575e-7 3.7290432730149077e-7 5563/84617/51807/10382/51422/7277/53632/10381/7278/112714/5571/7846/113457/347733/10376/4137/5562/10383/84790/5564/801/5565/7280 23 Vaccinia_virus R-HSA-442755 Activation of NMDA receptors and postsynaptic events 54/3478 93/10654 3.7081976139380517e-7 1.0699695198550418e-6 4.3343625619056613e-7 5923/5170/5563/84617/3838/4893/2904/5567/51807/10382/5594/5568/51422/7277/114/53632/10381/7278/5573/112714/107/6714/5566/5571/7846/5576/113457/347733/3084/10376/6195/4137/2066/1742/5577/88/1385/6196/5562/10383/84790/8874/6197/3845/3265/5564/801/5565/5924/814/7280/5879/5595/64130 54 Vaccinia_virus R-HSA-8851708 Signaling by FGFR2 IIIa TM 17/3478 19/10654 4.3427241317802616e-7 1.2504517510427573e-6 5.065481917581529e-7 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/2247/5439/5432/22916 17 Vaccinia_virus R-HSA-933542 TRAF6 mediated NF-kB activation 20/3478 24/10654 4.4051586914211744e-7 1.2657976737797357e-6 5.127647046358345e-7 1147/351/7186/4790/57506/4214/7706/8517/5970/4792/4793/3146/23586/64135/6288/7189/6285/84282/3551/4791 20 Vaccinia_virus R-HSA-9022692 Regulation of MECP2 expression and activity 25/3478 33/10654 4.6230886251198543e-7 1.3256682703501032e-6 5.370178134878244e-7 27161/8841/2290/79718/9212/57690/27327/192670/9611/28996/2874/9612/5566/6907/3064/192669/3066/3065/23112/1385/25942/4343/26523/801/814 25 Vaccinia_virus R-HSA-209543 p75NTR recruits signalling complexes 13/3478 13/10654 4.710302866656908e-7 1.3423393971851478e-6 5.43771156146444e-7 4804/5584/8767/8878/4615/7316/4803/3654/7189/6233/7311/3551/7314 13 Vaccinia_virus R-HSA-209560 NF-kB is activated and signals survival 13/3478 13/10654 4.710302866656908e-7 1.3423393971851478e-6 5.43771156146444e-7 4804/4790/8878/7316/5970/4792/4803/3654/7189/6233/7311/3551/7314 13 Vaccinia_virus R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13/3478 13/10654 4.710302866656908e-7 1.3423393971851478e-6 5.43771156146444e-7 7531/7532/10971/7533/2810/11200/7534/891/983/995/1111/7465/7529 13 Vaccinia_virus R-HSA-5663220 RHO GTPases Activate Formins 74/3478 140/10654 5.352043462079503e-7 1.5220903891129592e-6 6.165868724280504e-7 5905/11130/84617/5903/71/1783/1058/991/1856/51807/10382/9212/389/6722/388/7277/348995/55920/79023/10381/57122/79980/7278/6232/332/112714/1780/5528/3688/5048/5501/8655/4085/5216/81624/6714/23279/79902/3796/1730/5519/699/7846/113457/347733/51466/22919/10376/23002/51143/998/5527/1855/701/1857/7514/23380/5518/10383/29984/5347/387/1729/60/84790/5217/6396/55746/140735/7280/5879/5515/1778/5516 74 Vaccinia_virus R-HSA-1295596 Spry regulation of FGF signaling 15/3478 16/10654 5.551530356889205e-7 1.5596084268339856e-6 6.317851350959636e-7 5594/7316/673/6714/8569/867/6233/2885/7311/5518/5781/7314/5595/5515/5516 15 Vaccinia_virus R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 15/3478 16/10654 5.551530356889205e-7 1.5596084268339856e-6 6.317851350959636e-7 4605/7027/286826/5934/1869/1875/890/983/5933/5928/91750/1874/3065/55957/132660 15 Vaccinia_virus R-HSA-205043 NRIF signals cell death from the nucleus 15/3478 16/10654 5.551530356889205e-7 1.5596084268339856e-6 6.317851350959636e-7 4804/8878/23385/7316/5664/4803/7189/83464/6233/7311/5599/55851/51107/5663/7314 15 Vaccinia_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 15/3478 16/10654 5.551530356889205e-7 1.5596084268339856e-6 6.317851350959636e-7 8454/1147/8945/4790/5604/6500/8517/7316/79155/23291/6233/7311/3551/6416/7314 15 Vaccinia_virus R-HSA-9614657 FOXO-mediated transcription of cell death genes 15/3478 16/10654 5.551530356889205e-7 1.5596084268339856e-6 6.317851350959636e-7 2308/27113/2309/10018/4802/356/4303/1649/4800/10370/1387/6794/2033/4801/604 15 Vaccinia_virus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 15/3478 16/10654 5.551530356889205e-7 1.5596084268339856e-6 6.317851350959636e-7 23643/6885/23118/7099/7316/929/3656/10454/7189/6233/7311/353376/7314/148022/257397 15 Vaccinia_virus R-HSA-447115 Interleukin-12 family signaling 37/3478 57/10654 5.68822322993954e-7 1.5947751363292031e-6 6.460308931510282e-7 1072/6627/27250/3593/6775/3595/5908/1265/9987/4478/3313/6175/3185/6774/6772/6647/149233/5898/6950/3717/3458/3181/998/6648/5478/3716/3594/6888/302/51561/4282/375/7297/5721/3586/5034/3572 37 Vaccinia_virus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 58/3478 103/10654 5.815627312672072e-7 1.6272007733436e-6 6.591662642539531e-7 5295/23396/3643/1839/685/5290/3667/5291/3815/207/5594/2069/8074/930/2064/8395/4615/5528/2100/1950/4233/6714/2099/5519/8503/2261/5159/2247/29851/5880/3084/145957/2534/391/2264/3630/2066/3654/7189/9542/5527/2885/10718/7409/51135/8660/3932/5518/1956/5296/8394/5781/5156/5879/5595/5515/3556/5516 58 Vaccinia_virus R-HSA-76009 Platelet Aggregation (Plug Formation) 28/3478 39/10654 6.136822855839401e-7 1.713608801479349e-6 6.941694783876063e-7 151/5170/6464/5770/5747/207/3674/7094/5908/1277/150/54518/6850/6714/152/2244/2335/3690/1445/6654/2885/1398/2266/5906/2243/7450/9564/1278 28 Vaccinia_virus R-HSA-199418 Negative regulation of the PI3K/AKT network 61/3478 110/10654 6.16194280644854e-7 1.717161124131032e-6 6.956084964178909e-7 5295/23396/3643/1839/685/5290/3667/5291/3815/207/5594/2069/8074/930/2064/8395/4615/5528/2100/1950/4233/6714/2099/5519/8503/2261/5159/2247/29851/5880/10000/3084/145957/2534/391/5728/2264/3630/2066/3654/7189/208/9542/5527/2885/10718/7409/51135/8660/3932/5518/1956/5296/8394/5781/5156/5879/5595/5515/3556/5516 61 Vaccinia_virus R-HSA-8875878 MET promotes cell motility 29/3478 41/10654 6.421050194671736e-7 1.7857739999237658e-6 7.234030339801385e-7 255631/3675/85301/85440/5747/5908/1277/1280/1289/3912/3688/4233/3915/1301/6714/3910/1281/1290/2889/2335/3913/2885/1398/5906/50509/1399/1278/1302/5879 29 Vaccinia_virus R-HSA-9020591 Interleukin-12 signaling 32/3478 47/10654 6.66102453122176e-7 1.8488013979443162e-6 7.489349383274333e-7 1072/6627/27250/3593/6775/3595/5908/1265/9987/4478/3313/6175/3185/6647/5898/6950/3717/3458/3181/998/6648/5478/3716/3594/6888/302/4282/375/7297/5721/3586/5034 32 Vaccinia_virus R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 18/3478 21/10654 7.590992699824207e-7 2.1027049778513053e-6 8.517892861065899e-7 6118/2237/328/5982/54107/3978/5111/5426/6119/5427/5985/5984/5983/6117/5981/10714/5424/56655 18 Vaccinia_virus R-HSA-180786 Extension of Telomeres 23/3478 30/10654 9.414356026732334e-7 2.602571476451953e-6 1.0542812821196204e-6 6118/2237/7015/1763/5982/54107/3978/5557/5422/5111/5426/6119/5427/5985/5984/23649/5983/6117/5981/10714/5558/5424/56655 23 Vaccinia_virus R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 24/3478 32/10654 1.0841825184183117e-6 2.9852739324241783e-6 1.2093110438777025e-6 10694/84617/51807/10575/10382/7277/10381/7278/112714/7203/10576/908/6950/7846/113457/347733/10376/10574/10383/60/84790/22948/10693/7280 24 Vaccinia_virus R-HSA-5626467 RHO GTPases activate IQGAPs 24/3478 32/10654 1.0841825184183117e-6 2.9852739324241783e-6 1.2093110438777025e-6 84617/71/1495/1499/51807/10382/7277/10381/7278/112714/7846/999/113457/347733/10376/998/8826/10383/60/84790/801/7280/5879/4221 24 Vaccinia_virus R-HSA-5654741 Signaling by FGFR3 28/3478 40/10654 1.4081714812407853e-6 3.862014854492055e-6 1.5644719114149842e-6 5295/4893/6464/5290/5335/5594/8074/10817/7316/673/6714/8569/2261/867/2247/6654/6233/2885/7311/5518/3845/3265/5781/2591/7314/5595/5515/5516 28 Vaccinia_virus R-HSA-5675221 Negative regulation of MAPK pathway 28/3478 40/10654 1.4081714812407853e-6 3.862014854492055e-6 1.5644719114149842e-6 4893/1844/5604/8844/5594/5528/7316/673/1852/5605/5037/5519/5894/6233/5527/7311/5518/5536/4140/3845/3265/369/7529/7314/1846/5595/5515/5516 28 Vaccinia_virus R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 12/3478 12/10654 1.4462505224166999e-6 3.927562693229666e-6 1.5910248265182683e-6 834/835/58484/55367/472/843/8738/7157/8626/7161/839/317 12 Vaccinia_virus R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 12/3478 12/10654 1.4462505224166999e-6 3.927562693229666e-6 1.5910248265182683e-6 23368/8793/3486/355/8794/124446/8797/7157/8626/7161/7159/8795 12 Vaccinia_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 12/3478 12/10654 1.4462505224166999e-6 3.927562693229666e-6 1.5910248265182683e-6 3665/29110/7098/7316/3661/6233/10010/7311/7187/9641/7314/148022 12 Vaccinia_virus R-HSA-9020558 Interleukin-2 signaling 12/3478 12/10654 1.4462505224166999e-6 3.927562693229666e-6 1.5910248265182683e-6 6464/3561/6776/3560/6850/3718/3558/3716/3932/2185/6777/3559 12 Vaccinia_virus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12/3478 12/10654 1.4462505224166999e-6 3.927562693229666e-6 1.5910248265182683e-6 1147/8737/57506/841/7706/8517/23586/843/64135/84282/8772/3551 12 Vaccinia_virus R-HSA-111447 Activation of BAD and translocation to mitochondria 14/3478 15/10654 1.6016134056951973e-6 4.290589104231815e-6 1.7380839768615293e-6 596/7531/572/7532/207/10971/7533/2810/7534/10000/5534/208/637/7529 14 Vaccinia_virus R-HSA-5637810 Constitutive Signaling by EGFRvIII 14/3478 15/10654 1.6016134056951973e-6 4.290589104231815e-6 1.7380839768615293e-6 5295/4893/6464/5290/5335/1950/867/3320/6654/2885/1956/3845/3265/11140 14 Vaccinia_virus R-HSA-5637812 Signaling by EGFRvIII in Cancer 14/3478 15/10654 1.6016134056951973e-6 4.290589104231815e-6 1.7380839768615293e-6 5295/4893/6464/5290/5335/1950/867/3320/6654/2885/1956/3845/3265/11140 14 Vaccinia_virus R-HSA-6785631 ERBB2 Regulates Cell Motility 14/3478 15/10654 1.6016134056951973e-6 4.290589104231815e-6 1.7380839768615293e-6 1839/685/2069/2064/1950/51072/3084/145957/2066/9542/10718/387/1729/1956 14 Vaccinia_virus R-HSA-937039 IRAK1 recruits IKK complex 14/3478 15/10654 1.6016134056951973e-6 4.290589104231815e-6 1.7380839768615293e-6 1147/246330/8517/7316/7335/57162/3654/7189/6233/7311/7334/3551/57161/7314 14 Vaccinia_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 14/3478 15/10654 1.6016134056951973e-6 4.290589104231815e-6 1.7380839768615293e-6 54106/3665/4615/7316/7335/3654/7189/6233/51311/51135/7311/7334/51284/7314 14 Vaccinia_virus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 14/3478 15/10654 1.6016134056951973e-6 4.290589104231815e-6 1.7380839768615293e-6 1147/246330/8517/7316/7335/57162/3654/7189/6233/7311/7334/3551/57161/7314 14 Vaccinia_virus R-HSA-418217 G beta:gamma signalling through PLC beta 17/3478 20/10654 2.0078173383986824e-6 5.368391918305357e-6 2.1746934390703064e-6 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Vaccinia_virus R-HSA-201681 TCF dependent signaling in response to WNT 110/3478 233/10654 2.1145663244743853e-6 5.64291784084205e-6 2.285901736020378e-6 5718/27123/9070/5689/51176/8945/5684/8295/857/5720/6662/7015/7090/1487/6597/5682/1499/864/1459/5700/122706/5707/1856/207/1454/1452/5690/5717/5929/9491/23198/1460/143471/5706/7471/5705/8395/10197/6657/7534/64750/8452/5528/55366/7316/10213/5709/9978/5695/7091/54361/89780/1457/5714/4609/9861/5715/5519/5711/2932/5701/10524/5688/1387/5687/1455/5685/5683/5698/5708/5692/5686/5713/324/2033/54894/5699/8312/5710/5702/3065/7088/5719/208/57680/5704/6233/5527/1855/7474/5716/1857/7514/23072/7311/5518/7089/331/25776/6659/5694/5693/5721/5696/6259/5691/7314/4221/5515/5516 110 Vaccinia_virus R-HSA-5619115 Disorders of transmembrane transporters 87/3478 176/10654 2.418092976128974e-6 6.440497638343517e-6 2.608995053191788e-6 5718/23165/5689/5684/5903/5720/55706/7175/5682/9631/5700/122706/5707/10956/5690/285195/5717/9491/23198/1080/348995/143471/79023/5706/5705/57122/23636/10197/10762/23511/7316/10213/5709/335/5695/53371/3098/5714/23279/4927/9688/7415/9861/79902/5715/5711/9883/5701/5688/5687/5685/5683/682/5698/5708/5692/5686/5713/5699/6400/5710/5702/8086/6514/5719/6520/5704/6233/23225/5716/7311/9972/11160/8021/6396/129401/213/5694/55746/5693/5721/5696/5691/8480/6513/1356/7314 87 Vaccinia_virus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 23/3478 31/10654 2.5180917745045044e-6 6.693967577137694e-6 2.711673736359028e-6 3725/5601/5594/5528/5519/5598/1432/466/5602/6195/1385/2353/6196/5518/1386/6197/5599/5600/51231/1846/5595/5515/5516 23 Vaccinia_virus R-HSA-72172 mRNA Splicing 93/3478 191/10654 2.524864782426313e-6 6.699114413142612e-6 2.713758679236186e-6 10450/22827/23451/2963/6635/5434/5440/6633/220988/6432/8683/6431/6430/6632/6627/24148/10946/27339/11051/5430/4904/5436/9879/6428/3184/25804/55749/3178/23450/5441/3183/5438/5431/9092/55110/5093/22794/5435/10594/4686/6625/10713/11338/1655/9343/3185/4116/3190/5433/6626/24144/2962/22938/988/10236/5437/4670/23020/10189/6631/10949/55660/3181/5439/11193/1660/2521/3191/6638/57794/27316/6636/3187/1993/1665/10286/23524/6634/5094/51593/9775/3192/3312/6426/84991/5432/22916/56259/5725/10992/55339/6628/1994 93 Vaccinia_virus R-HSA-6783783 Interleukin-10 signaling 31/3478 47/10654 2.8432746497812564e-6 7.529513173894914e-6 3.050146700882378e-6 729230/3557/7124/3587/6351/3593/3553/1230/2919/5743/3383/3576/2357/2920/6352/6774/1435/1440/3627/7132/3552/6364/3716/6363/6347/7076/7297/3569/1234/3586/3554 31 Vaccinia_virus R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 18/3478 22/10654 2.8929767723468288e-6 7.631948247048301e-6 3.0916423451846807e-6 4000/3725/826/351/994/2309/10018/7531/356/823/2801/7001/993/995/6648/8851/5052/1020 18 Vaccinia_virus R-HSA-8863678 Neurodegenerative Diseases 18/3478 22/10654 2.8929767723468288e-6 7.631948247048301e-6 3.0916423451846807e-6 4000/3725/826/351/994/2309/10018/7531/356/823/2801/7001/993/995/6648/8851/5052/1020 18 Vaccinia_virus R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 44/3478 75/10654 3.008710848768524e-6 7.922175904076818e-6 3.2092112915621835e-6 23165/7919/5903/6432/8683/6431/6430/55706/7175/9631/6428/348995/79023/57122/23636/10762/55110/22794/23511/4686/53371/11338/4116/23279/4927/9688/79902/9883/10189/10482/8086/9877/23225/9972/9775/8021/6396/129401/2733/6426/55746/22916/84324/8480 44 Vaccinia_virus R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 27/3478 39/10654 3.0574675107063065e-6 8.035279890565909e-6 3.2550288289353066e-6 10694/9134/8841/8237/10575/26224/898/10517/7203/10576/908/6774/26272/26270/6950/55294/26190/10238/7157/10574/6468/10564/54461/22948/26234/10693/84261 27 Vaccinia_virus R-HSA-8986944 Transcriptional Regulation by MECP2 38/3478 62/10654 3.256670108048937e-6 8.542178284415325e-6 3.460369390532676e-6 27161/627/8841/2290/79718/5770/5468/2904/4986/9212/57690/27327/6657/192670/54487/9611/28996/2874/4233/9612/5566/4988/6907/3064/5728/192669/3066/3065/3654/23112/1385/25942/4343/6750/26523/801/814/28514 38 Vaccinia_virus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 15/3478 17/10654 3.2811832832555613e-6 8.542178284415325e-6 3.460369390532676e-6 1147/11035/4790/8737/8517/4615/7098/5970/4792/4793/1660/81030/3551/4791/148022 15 Vaccinia_virus R-HSA-5655862 Translesion synthesis by POLK 15/3478 17/10654 3.2811832832555613e-6 8.542178284415325e-6 3.460369390532676e-6 6118/5982/7316/5111/6119/51455/5985/5984/6233/51426/7311/5983/6117/5981/7314 15 Vaccinia_virus R-HSA-5656121 Translesion synthesis by POLI 15/3478 17/10654 3.2811832832555613e-6 8.542178284415325e-6 3.460369390532676e-6 6118/5982/7316/11201/5111/6119/51455/5985/5984/6233/7311/5983/6117/5981/7314 15 Vaccinia_virus R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 15/3478 17/10654 3.2811832832555613e-6 8.542178284415325e-6 3.460369390532676e-6 2308/857/2290/2309/57060/4303/1027/5934/1026/901/4089/1647/9314/4088/4087 15 Vaccinia_virus R-HSA-70326 Glucose metabolism 51/3478 91/10654 3.3308977496970026e-6 8.655334677918101e-6 3.5062081575757925e-6 5105/23165/7167/5903/2597/55706/7175/9631/5315/5567/2806/5568/348995/79023/57122/23636/5214/10762/23511/5528/53371/5230/3098/23279/4927/9688/79902/5566/5519/5106/9883/2023/226/2821/4190/8604/8086/23225/9972/5518/4191/8021/6396/129401/2026/230/55746/2027/8480/5515/5516 51 Vaccinia_virus R-HSA-5627123 RHO GTPases activate PAKs 19/3478 24/10654 3.7675896082602095e-6 9.753479640075495e-6 3.951058064343712e-6 3984/4638/4659/4627/2316/4771/10627/10398/4637/79784/998/4628/103910/5058/801/4660/4629/5500/5879 19 Vaccinia_virus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 19/3478 24/10654 3.7675896082602095e-6 9.753479640075495e-6 3.951058064343712e-6 596/1839/685/2309/5747/207/5594/2069/6722/1027/1950/10000/595/208/7514/1385/2353/1956/5595 19 Vaccinia_virus R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 69/3478 134/10654 4.356911269342593e-6 1.1258063634402038e-5 4.5605532336205856e-006 928/351/1072/5005/7018/5579/2153/5340/2316/3674/813/7094/7422/5578/5582/7414/7277/29106/5196/3827/1950/335/2621/308/5216/5768/710/6694/6647/7273/22927/27154/226/197/374354/2244/1893/81/5265/3309/7078/9948/2335/3690/334/87/3481/5478/2/10487/5473/88/2266/8407/1675/7076/3479/2243/7450/7040/10916/213/5660/801/350/7057/5627/967/5054 69 Vaccinia_virus R-HSA-1059683 Interleukin-6 signaling 11/3478 11/10654 4.439701272016415e-6 1.1261879600261418e-5 4.5620990514454385e-6 9021/6774/6772/867/3717/3716/3570/7297/5781/3569/3572 11 Vaccinia_virus R-HSA-193692 Regulated proteolysis of p75NTR 11/3478 11/10654 4.439701272016415e-6 1.1261879600261418e-5 4.5620990514454385e-6 4804/4790/23385/5970/5664/7189/6868/83464/55851/51107/5663 11 Vaccinia_virus R-HSA-3371378 Regulation by c-FLIP 11/3478 11/10654 4.439701272016415e-6 1.1261879600261418e-5 4.5620990514454385e-6 7186/8737/356/355/841/8797/8837/8772/8717/8743/8795 11 Vaccinia_virus R-HSA-5218900 CASP8 activity is inhibited 11/3478 11/10654 4.439701272016415e-6 1.1261879600261418e-5 4.5620990514454385e-6 7186/8737/356/355/841/8797/8837/8772/8717/8743/8795 11 Vaccinia_virus R-HSA-5625970 RHO GTPases activate KTN1 11/3478 11/10654 4.439701272016415e-6 1.1261879600261418e-5 4.5620990514454385e-6 3831/64837/3798/89953/3895/391/998/147700/3799/387/5879 11 Vaccinia_virus R-HSA-68689 CDC6 association with the ORC:origin complex 11/3478 11/10654 4.439701272016415e-6 1.1261879600261418e-5 4.5620990514454385e-6 5000/23594/1869/84515/1871/4998/990/1870/23595/5001/4999 11 Vaccinia_virus R-HSA-69416 Dimerization of procaspase-8 11/3478 11/10654 4.439701272016415e-6 1.1261879600261418e-5 4.5620990514454385e-6 7186/8737/356/355/841/8797/8837/8772/8717/8743/8795 11 Vaccinia_virus R-HSA-9013700 NOTCH4 Activation and Transmission of Signal to the Nucleus 11/3478 11/10654 4.439701272016415e-6 1.1261879600261418e-5 4.5620990514454385e-6 182/23385/7534/102/5664/4855/83464/54567/55851/51107/5663 11 Vaccinia_virus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 11/3478 11/10654 4.439701272016415e-6 1.1261879600261418e-5 4.5620990514454385e-6 6885/23118/7098/7316/10454/7189/6233/7311/7314/148022/257397 11 Vaccinia_virus R-HSA-9614399 Regulation of localization of FOXO transcription factors 11/3478 11/10654 4.439701272016415e-6 1.1261879600261418e-5 4.5620990514454385e-6 2308/2309/7532/207/10971/4303/2810/7534/10000/208/7529 11 Vaccinia_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 20/3478 26/10654 4.5665223424835704e-6 1.1562401177952002e-5 4.683837984304326e-6 57154/51377/10273/64750/7316/5501/4092/23327/7046/4088/9958/4087/5499/6233/7514/7048/7311/7040/5500/7314 20 Vaccinia_virus R-HSA-170670 Adenylate cyclase inhibitory pathway 13/3478 14/10654 4.600479904414872e-6 1.1563819723438471e-5 4.684412625949234e-6 2770/112/114/108/113/111/107/346562/2771/196883/115/109/2773 13 Vaccinia_virus R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 13/3478 14/10654 4.600479904414872e-6 1.1563819723438471e-5 4.684412625949234e-6 23368/79370/9540/332/64065/5876/7157/8626/604/7161/7159/10397/5875 13 Vaccinia_virus R-HSA-877312 Regulation of IFNG signaling 13/3478 14/10654 4.600479904414872e-6 1.1563819723438471e-5 4.684412625949234e-6 3460/5777/5770/9021/6772/8651/3459/7341/3717/3458/3716/5781/8554 13 Vaccinia_virus R-HSA-8983432 Interleukin-15 signaling 13/3478 14/10654 4.600479904414872e-6 1.1563819723438471e-5 4.684412625949234e-6 6464/3561/6776/3560/6774/3718/6654/2885/3716/9846/6655/6777/3601 13 Vaccinia_virus R-HSA-445717 Aquaporin-mediated transport 33/3478 52/10654 4.866992034840723e-6 1.2189482763570347e-5 4.937863813781489e-6 2788/54331/59345/5567/5568/10681/51764/112/94235/114/108/5573/113/55970/2778/111/107/2792/5566/2793/5576/2785/2783/2784/2782/2786/5577/196883/115/2791/109/2790/2787 33 Vaccinia_virus R-HSA-72165 mRNA Splicing - Minor Pathway 33/3478 52/10654 4.866992034840723e-6 1.2189482763570347e-5 4.937863813781489e-6 23451/2963/6635/5434/5440/6633/6432/6431/6632/24148/5430/4904/5436/23450/5441/5438/5431/5435/10594/4686/9343/5433/2962/5437/23020/5439/6636/6634/6426/5432/22916/10992/6628 33 Vaccinia_virus R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 21/3478 28/10654 5.247425890001162e-6 1.3118564725002904e-5 5.314227625632946e-6 10694/84617/10575/10382/7277/10381/7278/7203/10576/908/6950/7846/113457/347733/10574/10383/60/84790/22948/10693/7280 21 Vaccinia_virus R-HSA-163615 PKA activation 16/3478 19/10654 5.268082430428673e-6 1.3146475975033714e-5 5.3255342539942775e-6 5567/5568/112/114/108/5573/113/111/107/5566/5576/5577/196883/115/801/109 16 Vaccinia_virus R-HSA-1226099 Signaling by FGFR in disease 38/3478 63/10654 5.6350938027319955e-6 1.4037059202848585e-5 5.686302530965834e-6 5295/2963/8805/5434/5440/4893/11052/5290/5335/5430/5436/613/8074/5441/5438/5431/6776/5435/4686/6774/5433/6772/2962/399687/2261/5437/2247/2264/5439/6654/2885/9846/11160/3845/6777/3265/5432/22916 38 Vaccinia_virus R-HSA-167287 HIV elongation arrest and recovery 25/3478 36/10654 6.55865064173194e-6 1.6245550649760386e-5 6.5809450855575035e-6 2963/5434/5440/5430/5436/6749/5441/5438/5431/5435/5433/9150/2962/5437/8812/905/5439/6827/1025/11198/904/6829/51497/5432/8178 25 Vaccinia_virus R-HSA-167290 Pausing and recovery of HIV elongation 25/3478 36/10654 6.55865064173194e-6 1.6245550649760386e-5 6.5809450855575035e-6 2963/5434/5440/5430/5436/6749/5441/5438/5431/5435/5433/9150/2962/5437/8812/905/5439/6827/1025/11198/904/6829/51497/5432/8178 25 Vaccinia_virus R-HSA-111465 Apoptotic cleavage of cellular proteins 26/3478 38/10654 6.5685980966540195e-6 1.6245550649760386e-5 6.5809450855575035e-6 4000/1828/2934/1499/5747/63967/1829/841/100506658/7082/5339/5317/10134/329/1832/999/836/324/4137/1830/5580/6709/6093/839/840/7431 26 Vaccinia_virus R-HSA-5696394 DNA Damage Recognition in GG-NER 26/3478 38/10654 6.5685980966540195e-6 1.6245550649760386e-5 6.5809450855575035e-6 9318/83444/86/8450/7316/9978/64708/1643/10980/1642/10920/142/10987/6233/2873/7311/60/8533/5887/5886/50813/7508/7314/51138/8451/7528 26 Vaccinia_virus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 49/3478 88/10654 6.6013182629748945e-6 1.6297372182210747e-5 6.601937581697379e-6 8454/115106/8945/22995/22981/7531/10142/4659/11190/203068/7532/1454/10382/6500/7277/9133/5048/7316/891/8655/9738/983/6790/4957/5566/23291/7846/7283/3320/22919/10540/5577/6233/80254/7311/54930/5518/10133/10383/55835/5347/9662/1453/5108/8481/4660/5500/7314/1778 49 Vaccinia_virus R-HSA-1632852 Macroautophagy 52/3478 95/10654 6.820486509151609e-6 1.6781854289185956e-5 6.798197481387889e-6 5563/1459/389541/79065/9140/8878/9821/51422/7249/58528/1460/10533/53632/153129/7416/9474/192111/7316/8655/5289/1457/8678/6714/64223/8408/10226/5571/10325/29082/8649/128866/84971/6009/55054/81631/10542/6233/2475/55004/7311/84557/5562/10670/55626/3312/5564/5565/64121/57521/140735/7314/28956 52 Vaccinia_virus R-HSA-3000171 Non-integrin membrane-ECM interactions 36/3478 59/10654 6.821793476398334e-6 1.6781854289185956e-5 6.798197481387889e-6 1286/1287/3371/7276/1282/375790/1284/5578/1277/6383/1280/1289/3912/7448/1300/3688/3915/1301/3910/1281/1290/2247/2335/3690/87/1288/3913/3685/6382/50509/7040/1285/7057/1278/1302/3655 36 Vaccinia_virus R-HSA-111931 PKA-mediated phosphorylation of CREB 17/3478 21/10654 7.314869129167827e-6 1.7931139369729985e-5 7.263763848805687e-6 5567/5568/112/114/108/5573/113/111/107/5566/5576/5577/1385/196883/115/801/109 17 Vaccinia_virus R-HSA-500657 Presynaptic function of Kainate receptors 17/3478 21/10654 7.314869129167827e-6 1.7931139369729985e-5 7.263763848805687e-6 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/2791/2790/2787 17 Vaccinia_virus R-HSA-72202 Transport of Mature Transcript to Cytoplasm 47/3478 84/10654 8.493803024354682e-6 2.078430598715766e-5 8.419559256055506e-6 23165/7919/5903/6432/8683/6431/6430/55706/7175/9631/7884/6428/348995/79023/57122/23636/10762/55110/22794/23511/4686/53371/11338/4116/23279/4927/9688/79902/9883/10189/10482/8086/1977/9877/23225/9972/9775/8021/6396/129401/2733/6426/55746/22916/84324/8480/55339 47 Vaccinia_virus R-HSA-110312 Translesion synthesis by REV1 14/3478 16/10654 8.926835995739091e-6 2.169064535806779e-5 8.78671022295279e-6 6118/5982/7316/5111/6119/51455/5985/5984/6233/7311/5983/6117/5981/7314 14 Vaccinia_virus R-HSA-1433559 Regulation of KIT signaling 14/3478 16/10654 8.926835995739091e-6 2.169064535806779e-5 8.78671022295279e-6 5777/3815/10019/5578/9306/6714/8651/867/4067/2534/6654/2885/7525/3932 14 Vaccinia_virus R-HSA-156711 Polo-like kinase mediated events 14/3478 16/10654 8.926835995739091e-6 2.169064535806779e-5 8.78671022295279e-6 4605/2305/9133/286826/891/993/5928/91750/2033/995/55957/5347/7465/132660 14 Vaccinia_virus R-HSA-1963642 PI3K events in ERBB2 signaling 14/3478 16/10654 8.926835995739091e-6 2.169064535806779e-5 8.78671022295279e-6 5295/1839/685/5290/2069/2064/1950/3084/145957/2066/9542/2885/10718/1956 14 Vaccinia_virus R-HSA-114608 Platelet degranulation 66/3478 129/10654 9.22577871570472e-6 2.2340463368129443e-5 9.049946399553863e-6 928/351/1072/5005/7018/2153/5340/2316/3674/813/7094/7422/7414/7277/29106/5196/3827/1950/335/2621/308/5216/5768/710/6694/6647/7273/22927/27154/226/197/374354/2244/1893/81/5265/3309/7078/9948/2335/3690/334/87/3481/5478/2/10487/5473/88/2266/8407/1675/7076/3479/2243/7450/7040/10916/213/5660/801/350/7057/5627/967/5054 66 Vaccinia_virus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 18/3478 23/10654 9.226530719545157e-6 2.2340463368129443e-5 9.049946399553863e-6 7321/6497/64750/7323/8239/54778/7316/9611/9612/4089/23327/4088/142/3065/4087/6233/7311/7314 18 Vaccinia_virus R-HSA-177929 Signaling by EGFR 31/3478 49/10654 1.034708910660941e-5 2.5009979777755727e-5 1.0131346548769753e-5 5295/1839/4893/6464/685/5290/5335/2060/2069/7316/1950/102/6714/867/9146/1445/998/6868/6654/6233/2885/7311/1956/29924/8874/3845/3265/5781/10254/5829/7314 31 Vaccinia_virus R-HSA-9006115 Signaling by NTRK2 (TRKB) 19/3478 25/10654 1.0874997414486388e-5 2.624019410986698e-5 1.0629696720926545e-5 5295/627/4893/6464/5290/5335/2904/7074/10817/6714/2534/6654/2885/8851/3845/3265/1020/5781/5879 19 Vaccinia_virus R-HSA-437239 Recycling pathway of L1 30/3478 47/10654 1.1087527767879608e-5 2.6706479927849142e-5 1.0818585446736534e-5 1173/84617/71/7430/51807/10382/5594/7277/10381/4478/7278/112714/8650/6714/7846/113457/347733/1808/10376/6195/5962/6196/1759/1213/10383/1211/60/84790/6197/7280 30 Vaccinia_virus R-HSA-3000170 Syndecan interactions 20/3478 27/10654 1.2192555961569262e-5 2.9317170150648312e-5 1.1876155569291696e-5 3371/5578/1277/6383/1289/7448/3688/1281/1290/2247/2335/3690/87/3685/6382/50509/7040/7057/1278/3655 20 Vaccinia_virus R-HSA-422356 Regulation of insulin secretion 44/3478 78/10654 1.2342443929331353e-5 2.962614357387162e-5 1.200131827845227e-5 2788/54331/59345/2740/5567/2770/5578/5568/10681/51764/112/94235/114/3708/4082/5573/150/55970/2778/111/2767/2792/152/5566/2793/5576/2785/2783/2784/2782/3630/2776/6514/2786/2771/5577/8826/5906/2182/773/2791/6513/2790/2787 44 Vaccinia_virus R-HSA-5654743 Signaling by FGFR4 27/3478 41/10654 1.3087837652793722e-5 3.136099506768046e-5 1.2704093004806145e-5 5295/4893/6464/5290/5335/5594/8074/10817/7316/673/6714/8569/867/2247/2264/6654/6233/2885/7311/5518/3845/3265/5781/7314/5595/5515/5516 27 Vaccinia_virus R-HSA-5357786 TNFR1-induced proapoptotic signaling 12/3478 13/10654 1.3148893351428738e-5 3.136612573018991e-5 1.2706171395927209e-5 7124/7186/8737/7375/841/27005/7128/7132/9099/8772/8717/1540 12 Vaccinia_virus R-HSA-8847993 ERBB2 Activates PTK6 Signaling 12/3478 13/10654 1.3148893351428738e-5 3.136612573018991e-5 1.2706171395927209e-5 1839/685/2069/2064/1950/5753/3084/145957/2066/9542/10718/1956 12 Vaccinia_virus R-HSA-5218920 VEGFR2 mediated vascular permeability 21/3478 29/10654 1.315791989114826e-5 3.136612573018991e-5 1.2706171395927209e-5 5170/857/1495/1499/207/10451/1500/64223/1003/10000/3320/4846/3728/208/7410/2475/7409/5058/801/5879/253260 21 Vaccinia_virus R-HSA-110056 MAPK3 (ERK1) activation 10/3478 10/10654 1.3626349578818543e-5 3.204158602150031e-5 1.2979795059441129e-5 5604/983/3717/3716/3570/7297/5781/3569/3572/5595 10 Vaccinia_virus R-HSA-1250342 PI3K events in ERBB4 signaling 10/3478 10/10654 1.3626349578818543e-5 3.204158602150031e-5 1.2979795059441129e-5 5295/1839/685/5290/2069/3084/145957/2066/9542/10718 10 Vaccinia_virus R-HSA-193697 p75NTR regulates axonogenesis 10/3478 10/10654 1.3626349578818543e-5 3.204158602150031e-5 1.2979795059441129e-5 4804/57142/4974/4168/65078/84894/396/4803/4099/387 10 Vaccinia_virus R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 10/3478 10/10654 1.3626349578818543e-5 3.204158602150031e-5 1.2979795059441129e-5 5563/51422/53632/1432/5571/5600/5564/6300/5565/10891 10 Vaccinia_virus R-HSA-390450 Folding of actin by CCT/TriC 10/3478 10/10654 1.3626349578818543e-5 3.204158602150031e-5 1.2979795059441129e-5 10694/10575/7203/10576/908/6950/10574/60/22948/10693 10 Vaccinia_virus R-HSA-450341 Activation of the AP-1 family of transcription factors 10/3478 10/10654 1.3626349578818543e-5 3.204158602150031e-5 1.2979795059441129e-5 3725/5601/5594/1432/5602/2353/1386/5599/5600/5595 10 Vaccinia_virus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 10/3478 10/10654 1.3626349578818543e-5 3.204158602150031e-5 1.2979795059441129e-5 6885/23118/7316/3656/10454/7189/6233/7311/7314/257397 10 Vaccinia_virus R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 10/3478 10/10654 1.3626349578818543e-5 3.204158602150031e-5 1.2979795059441129e-5 2308/2309/4303/23410/7295/8850/1387/10628/2033/23411 10 Vaccinia_virus R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 15/3478 18/10654 1.3699571830550593e-5 3.2159164381885716e-5 1.3027425130568182e-5 1839/4893/5578/5594/5598/6195/6654/2885/1385/6196/1956/6197/3845/3265/5595 15 Vaccinia_virus R-HSA-3000178 ECM proteoglycans 43/3478 76/10654 1.3960788585295066e-5 3.271690725995544e-5 1.3253362393734563e-5 1286/1287/3371/1282/351/375790/1299/3674/256076/1284/1277/1280/1289/3912/7448/3688/1298/3915/1462/3910/1281/1297/1290/4148/4038/2335/1758/3690/3694/1288/3913/3685/1292/4060/50509/1293/7040/3687/1285/131873/1278/1291/5054 43 Vaccinia_virus R-HSA-8953750 Transcriptional Regulation by E2F6 24/3478 35/10654 1.4137176255023707e-5 3.30743059344727e-5 1.3398141792189963e-5 5888/7027/2146/8317/6045/80012/5931/79813/4149/1869/1876/1911/5928/23512/1111/672/5932/8726/648/317/23429/10919/6015/6241 24 Vaccinia_virus R-HSA-167044 Signalling to RAS 16/3478 20/10654 1.830914279854862e-5 4.276250046541289e-5 1.7322753371130584e-5 4893/6464/5899/6714/5898/1432/4914/4803/5603/6654/2885/5900/3845/5600/3265/6300 16 Vaccinia_virus R-HSA-373760 L1CAM interactions 61/3478 119/10654 1.8418003150343947e-5 4.2872158593657764e-5 1.7367175018369434e-5 6331/1173/84617/6711/71/7430/5604/1459/51807/10048/3674/10382/5594/1460/7277/10381/3678/4478/7278/3912/112714/3688/3672/8650/1272/1457/3915/6714/5605/7846/113457/347733/3690/1808/10376/6195/214/6386/2048/1742/287/7410/6709/5962/3685/6196/1759/1213/10383/1956/1211/60/84790/27255/6197/3312/5058/100133941/7280/5879/5595 61 Vaccinia_virus R-HSA-9612973 Autophagy 61/3478 119/10654 1.8418003150343947e-5 4.2872158593657764e-5 1.7367175018369434e-5 5563/1459/1915/389541/79065/9140/8878/9821/51422/7249/58528/1080/1460/10533/10013/53632/153129/7416/9474/192111/7316/8655/5289/1457/8678/6714/64223/8408/3043/10226/5571/10325/29082/8649/3320/128866/84971/6009/55054/81631/10542/6233/3326/2475/55004/7311/84557/5562/10670/55626/7251/7431/3312/5564/11315/5565/64121/57521/140735/7314/28956 61 Vaccinia_virus R-HSA-71291 Metabolism of amino acids and derivatives 159/3478 372/10654 2.15191161323058e-5 5.0006670877925385e-5 2.0257309958528773e-5 6158/440/5718/5689/6138/6144/6203/5684/6227/27165/9349/4736/1728/5720/6206/6194/6234/6191/6166/6128/5682/51121/6132/6147/6159/6129/3620/5160/6217/5700/3028/122706/5707/2806/191/6230/6222/1743/6176/383/6152/5690/6136/6125/5717/9491/23198/6224/6146/6154/51065/6141/143471/6202/5706/6123/5705/10197/875/6232/6134/6169/6160/6164/6155/10213/5709/6175/6218/5695/9380/6209/5714/6193/6173/6210/6231/6229/11224/6205/6165/9861/6130/5715/6142/6167/9061/5711/6204/5701/5688/6228/23521/5687/116832/1152/5832/23474/5685/5683/5698/5708/7965/8604/5692/5686/5713/445/6192/6999/140801/6156/5699/6235/6143/5710/6181/6124/5702/26227/6207/5719/6139/6520/5704/6233/5716/7311/501/6223/25873/3921/6188/6189/29968/8424/6135/6201/5860/6161/6303/5694/9045/6187/6168/5693/6208/8942/6157/5721/6137/5696/6170/5691/200916/6122/6133/7296/4942 159 Vaccinia_virus R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 46/3478 84/10654 2.245645689205144e-5 5.2097475369332066e-5 2.1104278450962564e-5 5105/7124/1019/8841/4790/79718/5468/29079/892/9440/6721/51129/1051/7471/6720/6837/3952/688/5465/9611/5469/81857/1050/5970/9612/1024/9314/9968/1387/6907/9439/2033/9967/7026/6256/896/10498/9370/9477/112950/10499/7040/9412/8202/8648/10891 46 Vaccinia_virus R-HSA-451927 Interleukin-2 family signaling 28/3478 44/10654 2.366019331831152e-5 5.4798273822510794e-5 2.219835071054399e-5 5295/5777/6464/5290/5291/3561/6775/6776/3560/6774/6850/3718/6772/8503/3558/3717/3636/6654/2885/3716/9846/3932/2185/6655/5296/6777/3559/3601 28 Vaccinia_virus R-HSA-1170546 Prolactin receptor signaling 13/3478 15/10654 2.409311214609272e-5 5.561493387056402e-5 2.2529173287486703e-5 8454/8945/2690/6500/6776/9978/3717/5618/2688/5617/6777/2689/5781 13 Vaccinia_virus R-HSA-69183 Processive synthesis on the lagging strand 13/3478 15/10654 2.409311214609272e-5 5.561493387056402e-5 2.2529173287486703e-5 6118/2237/1763/3978/5557/5422/5111/6119/23649/6117/10714/5558/5424 13 Vaccinia_virus R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 27/3478 42/10654 2.5270875655987723e-5 5.8236543733016636e-5 2.3591166870376487e-5 9070/51176/8945/6662/7090/1487/1499/207/5929/6657/7534/7316/7091/324/3065/7088/208/57680/6233/7514/7311/7089/331/25776/6659/7314/4221 27 Vaccinia_virus R-HSA-8940973 RUNX2 regulates osteoblast differentiation 18/3478 24/10654 2.560335405340003e-5 5.890472651820439e-5 2.3861842473268432e-5 25/8841/23462/5594/3280/5925/10013/1277/865/4094/10413/6714/7525/23493/25937/367/860/5595 18 Vaccinia_virus R-HSA-110373 Resolution of AP sites via the multiple-nucleotide patch replacement pathway 19/3478 26/10654 2.799800118135121e-5 6.430718347623786e-5 2.6050335392616203e-5 6118/2237/328/5982/54107/3978/5111/5426/6119/5427/5985/142/5984/5983/6117/5981/10714/5424/56655 19 Vaccinia_virus R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 25/3478 38/10654 2.8158034702747956e-5 6.456767891275815e-5 2.615586004978156e-5 1072/6627/27250/6775/5908/1265/9987/4478/3313/6175/3185/6647/5898/6950/3458/3181/998/6648/5478/6888/302/4282/375/5721/3586 25 Vaccinia_virus R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 23/3478 34/10654 3.0109330265369942e-5 6.881422841177784e-5 2.787610392816081e-5 2963/5434/5440/5430/5436/6749/5441/5438/5431/5435/5433/9150/2962/5437/5439/6827/1025/11198/904/6829/51497/5432/8178 23 Vaccinia_virus R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 23/3478 34/10654 3.0109330265369942e-5 6.881422841177784e-5 2.787610392816081e-5 2963/5434/5440/5430/5436/6749/5441/5438/5431/5435/5433/9150/2962/5437/5439/6827/1025/11198/904/6829/51497/5432/8178 23 Vaccinia_virus R-HSA-8874081 MET activates PTK2 signaling 21/3478 30/10654 3.0353948220627413e-5 6.925900870769187e-5 2.8056280935739895e-5 255631/3675/85301/5747/1277/1280/1289/3912/3688/4233/3915/1301/6714/3910/1281/1290/2335/3913/50509/1278/1302 21 Vaccinia_virus R-HSA-381042 PERK regulates gene expression 22/3478 32/10654 3.050012280368995e-5 6.947807579458976e-5 2.8145023293571227e-5 440/9709/1965/4802/5073/1051/1649/3576/3484/4800/1054/8894/3309/4801/6347/11340/467/8570/23016/54512/167227/1968 22 Vaccinia_virus R-HSA-170968 Frs2-mediated activation 11/3478 12/10654 3.736765951761337e-5 8.484296464245004e-5 3.436921919393947e-5 5604/5594/673/5605/2889/4914/4803/5906/1399/7529/5595 11 Vaccinia_virus R-HSA-2197563 NOTCH2 intracellular domain regulates transcription 11/3478 12/10654 3.736765951761337e-5 8.484296464245004e-5 3.436921919393947e-5 55534/3280/84441/10046/2033/3002/4853/9794/1385/388585/3516 11 Vaccinia_virus R-HSA-1474244 Extracellular matrix organization 131/3478 301/10654 4.118313849926018e-5 9.335294078801202e-5 3.781654375072043e-5 255631/3675/1310/8174/1286/871/1287/3371/826/7276/1282/1308/1294/351/85301/169044/7373/4052/960/10491/1511/5340/4239/283208/375790/7412/1299/91522/3674/256076/823/3684/1284/1991/5578/136227/5045/1305/23385/4318/4312/3383/3678/1277/6383/4237/1280/1289/3912/7448/1307/6696/50848/649/1300/3688/4313/3672/1298/667/102/8076/3695/5339/3915/1301/84570/1462/4015/3910/1281/1297/1290/4148/4038/1303/999/650/2247/836/2244/682/2335/1758/3690/3694/2200/1295/87/1288/6868/3913/2/652/726/1306/2266/3685/1292/4060/81578/7076/4236/2243/3791/7450/6382/50509/1293/7040/3687/57642/340267/1285/131873/30008/80781/7057/1278/5479/3689/1296/5663/977/4323/1302/5034/3676/1291/5054/3655 131 Vaccinia_virus R-HSA-110320 Translesion Synthesis by POLH 15/3478 19/10654 4.5317657081007816e-5 1.0255711610652912e-4 4.154508294492117e-5 6118/5982/7316/5111/7415/6119/5985/25898/5984/6233/7311/5983/6117/5981/7314 15 Vaccinia_virus R-HSA-445144 Signal transduction by L1 16/3478 21/10654 5.3490818540567125e-5 1.2085609082982947e-4 4.8957854008967594e-5 5604/1459/3674/5594/1460/3678/3688/1457/5605/3690/7410/3685/1956/5058/5879/5595 16 Vaccinia_virus R-HSA-73933 Resolution of Abasic Sites (AP sites) 25/3478 39/10654 5.4170847978101946e-5 1.221931994294319e-4 4.949950621006058e-5 6118/2237/4350/328/4913/7515/5982/54107/3978/6996/5111/5426/6119/5427/5985/142/5984/4595/4968/5983/6117/5981/10714/5424/56655 25 Vaccinia_virus R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission 94/3478 206/10654 6.0058702808221715e-5 1.3525415185266192e-4 5.479039554434262e-5 2788/5923/5170/5563/1173/84617/3838/4893/54331/5579/2904/59345/5567/2770/51807/2550/4646/10382/5578/5594/5568/51422/5582/10681/51764/112/7277/94235/114/53632/10381/108/7278/5573/112714/113/55970/2569/111/107/9568/2792/346562/6714/23229/5566/5571/2793/2567/7846/5576/113457/347733/3084/2785/10376/6195/2783/4137/2784/2782/2066/2786/2771/1742/5577/88/1385/6196/5562/10383/84790/8874/6197/3845/196883/3759/115/3265/5564/801/5565/5924/2791/814/7280/109/2773/5879/5595/4193/64130/2790/2787 94 Vaccinia_virus R-HSA-389356 CD28 co-stimulation 22/3478 33/10654 6.331124967719517e-5 1.4234753377096642e-4 5.7663868896009945e-5 5295/5170/5290/207/9020/6714/64223/8503/4067/10000/2534/998/208/2885/7525/2475/7409/3932/5296/5058/5879/253260 22 Vaccinia_virus R-HSA-169893 Prolonged ERK activation events 12/3478 14/10654 6.443937403351224e-5 1.4302649525066416e-4 5.793891086346494e-5 5604/5594/673/5605/2889/4914/4803/1398/5906/1399/7529/5595 12 Vaccinia_virus R-HSA-174411 Polymerase switching on the C-strand of the telomere 12/3478 14/10654 6.443937403351224e-5 1.4302649525066416e-4 5.793891086346494e-5 5982/5557/5422/5111/5985/5984/23649/5983/5981/10714/5558/5424 12 Vaccinia_virus R-HSA-3371568 Attenuation phase 12/3478 14/10654 6.443937403351224e-5 1.4302649525066416e-4 5.793891086346494e-5 3303/3337/3305/1387/3320/2033/3326/3306/3304/3312/2288/10728 12 Vaccinia_virus R-HSA-418885 DCC mediated attractive signaling 12/3478 14/10654 6.443937403351224e-5 1.4302649525066416e-4 5.793891086346494e-5 9423/5747/4690/7204/1793/6714/2534/998/8976/1630/3983/5879 12 Vaccinia_virus R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 12/3478 14/10654 6.443937403351224e-5 1.4302649525066416e-4 5.793891086346494e-5 6118/4436/9156/2956/4292/3978/5111/5395/6119/6117/10714/5424 12 Vaccinia_virus R-HSA-69091 Polymerase switching 12/3478 14/10654 6.443937403351224e-5 1.4302649525066416e-4 5.793891086346494e-5 5982/5557/5422/5111/5985/5984/23649/5983/5981/10714/5558/5424 12 Vaccinia_virus R-HSA-69109 Leading Strand Synthesis 12/3478 14/10654 6.443937403351224e-5 1.4302649525066416e-4 5.793891086346494e-5 5982/5557/5422/5111/5985/5984/23649/5983/5981/10714/5558/5424 12 Vaccinia_virus R-HSA-69166 Removal of the Flap Intermediate 12/3478 14/10654 6.443937403351224e-5 1.4302649525066416e-4 5.793891086346494e-5 6118/2237/1763/5557/5422/5111/6119/23649/6117/10714/5558/5424 12 Vaccinia_virus R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 13/3478 16/10654 8.981364213095838e-5 1.9902703096220378e-4 8.062428843082243e-5 2648/55534/3280/84441/10046/50674/22938/8850/1387/2033/9794/3516/4851 13 Vaccinia_virus R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 30/3478 51/10654 1.0432487249906899e-4 2.3081461407541622e-4 9.350118890533675e-5 84617/5321/1783/51807/10382/5050/55860/7277/10381/23299/7278/112714/1780/5048/8655/832/5870/636/7846/113457/347733/10376/51143/10540/10383/84790/5049/140735/7280/1778 30 Vaccinia_virus R-HSA-2586552 Signaling by Leptin 10/3478 11/10654 1.0549283264683981e-4 2.31549244399165e-4 9.379878188467032e-5 3667/3953/9021/3952/6776/6774/3717/8660/6777/5781 10 Vaccinia_virus R-HSA-351906 Apoptotic cleavage of cell adhesion proteins 10/3478 11/10654 1.0549283264683981e-4 2.31549244399165e-4 9.379878188467032e-5 1828/1499/1829/100506658/7082/5317/1832/999/836/1830 10 Vaccinia_virus R-HSA-4755510 SUMOylation of immune response proteins 10/3478 11/10654 1.0549283264683981e-4 2.31549244399165e-4 9.379878188467032e-5 51588/8517/10210/5970/4792/7341/7329/6612/9641/4791 10 Vaccinia_virus R-HSA-5603041 IRAK4 deficiency (TLR2/4) 10/3478 11/10654 1.0549283264683981e-4 2.31549244399165e-4 9.379878188467032e-5 23643/10333/7099/4615/7096/929/114609/695/51135/7097 10 Vaccinia_virus R-HSA-8934903 Receptor Mediated Mitophagy 10/3478 11/10654 1.0549283264683981e-4 2.31549244399165e-4 9.379878188467032e-5 1459/9140/1460/9474/192111/1457/6714/8408/81631/84557 10 Vaccinia_virus R-HSA-111996 Ca-dependent events 24/3478 38/10654 1.0810940289358799e-4 2.3654269037538605e-4 9.582158766489132e-5 3838/5321/5567/5578/5594/5568/5582/112/114/108/5573/113/111/107/5566/5576/5577/5580/1385/196883/115/801/814/109 24 Vaccinia_virus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 24/3478 38/10654 1.0810940289358799e-4 2.3654269037538605e-4 9.582158766489132e-5 7020/4605/7021/3815/7422/4869/4839/51741/2064/348/1026/2099/4609/3329/10370/7341/1387/7913/2033/7022/7329/29028/1956/7528 24 Vaccinia_virus R-HSA-190840 Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane 14/3478 18/10654 1.1078096753605366e-4 2.4200574138396583e-4 9.803462675861963e-5 84617/51807/10382/7277/10381/7278/112714/7846/113457/347733/10376/10383/84790/7280 14 Vaccinia_virus R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 23/3478 36/10654 1.1632671416847892e-4 2.5372047106038317e-4 1.0278017182229468e-4 26999/25/71/5747/4690/10006/10458/5594/10094/10152/998/695/8976/2885/7454/10097/23191/60/10095/3071/10109/5879/5595 23 Vaccinia_virus R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs 63/3478 130/10654 1.1970234411474066e-4 2.6067255754546513e-4 1.0559640750274209e-4 5718/5689/25/5684/5720/902/2624/5682/6929/5700/122706/5707/5690/2625/5717/9491/23198/143471/6938/5706/5705/10197/7316/10213/5709/865/5695/4331/10413/5714/9861/5715/5711/5701/5688/5687/5685/5683/5698/5708/5692/5686/5713/5699/4602/5710/5702/83737/861/5719/5704/6233/5716/7311/7161/5694/1022/5693/5721/4297/5696/5691/7314 63 Vaccinia_virus R-HSA-8852135 Protein ubiquitination 42/3478 79/10654 1.2461929296746037e-4 2.7095403572987854e-4 1.0976135363406822e-4 11065/7319/7321/65264/7320/10477/92912/7336/7326/5591/7323/8239/7316/7317/54926/55236/56254/8915/5111/7415/3093/7322/9810/7347/118424/29089/7328/7324/6233/7327/23168/7311/10670/55284/27338/7334/7874/7332/997/6596/80349/7314 42 Vaccinia_virus R-HSA-622312 Inflammasomes 15/3478 20/10654 1.2634319992838486e-4 2.7427168009531825e-4 1.1110530533217148e-4 834/596/351/4790/9447/58484/7295/29108/5970/598/10628/3326/4210/114548/4791 15 Vaccinia_virus R-HSA-5673000 RAF activation 21/3478 32/10654 1.313157981436883e-4 2.8373226275976336e-4 1.1493771313011884e-4 4893/5604/8844/5528/673/6714/5605/5519/3717/5894/5527/5518/4140/3845/3265/369/801/5245/7529/5515/5516 21 Vaccinia_virus R-HSA-73863 RNA Polymerase I Transcription Termination 21/3478 32/10654 1.313157981436883e-4 2.8373226275976336e-4 1.1493771313011884e-4 5434/5440/902/9015/9014/404672/5441/51082/5435/4331/9013/7343/2966/5437/2965/2068/2071/2968/2967/6908/1022 21 Vaccinia_virus R-HSA-8941326 RUNX2 regulates bone development 21/3478 32/10654 1.313157981436883e-4 2.8373226275976336e-4 1.1493771313011884e-4 25/8841/23462/5594/3280/4086/5925/10013/1277/865/4094/9759/10413/6714/4089/7525/23493/25937/367/860/5595 21 Vaccinia_virus R-HSA-429914 Deadenylation-dependent mRNA decay 32/3478 56/10654 1.3353734680319497e-4 2.876348760846423e-4 1.1651863116330181e-4 1656/9924/80153/5073/27257/4849/25804/4850/255967/26986/10605/9337/25904/246175/4848/23019/1981/1973/1977/1975/55571/11340/9775/54464/57472/85456/29883/23016/54512/1974/167227/80349 32 Vaccinia_virus R-HSA-977443 GABA receptor activation 32/3478 56/10654 1.3353734680319497e-4 2.876348760846423e-4 1.1651863116330181e-4 2788/54331/2770/2550/112/94235/114/108/113/55970/2569/111/107/9568/2792/346562/23229/2793/2567/2785/2783/2784/2782/2786/2771/196883/3759/115/109/2773/2790/2787 32 Vaccinia_virus R-HSA-2424491 DAP12 signaling 20/3478 30/10654 1.372746553091551e-4 0.00029522577267574504 1.1959364380480496e-4 5295/4893/6464/5290/5335/5291/3937/5336/10451/6850/2534/695/6654/2885/7410/3932/5296/3845/3265/5879 20 Vaccinia_virus R-HSA-3371571 HSF1-dependent transactivation 17/3478 24/10654 1.4192496875145357e-4 3.0475361507095066e-4 1.2345329799188048e-4 3303/84335/1410/3337/3305/64223/1387/3320/2033/3326/2475/3306/3304/3312/57521/2288/10728 17 Vaccinia_virus R-HSA-180024 DARPP-32 events 18/3478 26/10654 1.433023784978607e-4 3.0676011471334944e-4 1.242661152515411e-4 5567/5532/5568/5573/5530/5528/5566/5519/5576/5534/5499/5577/5144/5518/801/1020/5515/5516 18 Vaccinia_virus R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 18/3478 26/10654 1.433023784978607e-4 3.0676011471334944e-4 1.242661152515411e-4 80010/83990/5888/9156/1763/7486/10111/675/472/580/116028/641/10524/4683/79728/672/5932/7156 18 Vaccinia_virus R-HSA-112043 PLC beta mediated events 31/3478 54/10654 1.5078453678131268e-4 3.2227867815141676e-4 1.3055256352248156e-4 3838/5321/5567/2770/2781/5578/5594/5568/5582/112/114/3708/108/5573/2775/113/111/107/346562/5566/5576/2771/5577/5580/1385/196883/115/801/814/109/2773 31 Vaccinia_virus R-HSA-68877 Mitotic Prometaphase 90/3478 200/10654 1.5748688427455004e-4 3.360852615104034e-4 1.3614550209769714e-4 10844/115106/4926/5905/11130/22995/84617/5903/22981/7531/10142/1459/55869/1783/1058/11190/991/203068/51807/7532/1454/10382/9212/1460/23244/7277/348995/55920/79023/9133/10381/57122/79980/7278/6232/332/112714/1780/10051/5885/5528/5048/891/5501/8655/4085/9738/1457/983/4957/23279/79902/5566/3796/5519/699/7846/113457/7283/347733/3320/22919/80097/8243/9126/10376/51143/10540/5577/5527/80254/701/7514/54930/5518/10383/55835/5347/84790/6396/9662/1453/5108/55746/8481/140735/7280/5515/1778/5516 90 Vaccinia_virus R-HSA-5655253 Signaling by FGFR2 in disease 26/3478 43/10654 1.6007135657987792e-4 3.4107512132789373e-4 1.381668551531578e-4 5295/2963/5434/5440/4893/5290/5335/5430/5436/8074/5441/5438/5431/5435/4686/5433/2962/5437/2247/5439/6654/2885/3845/3265/5432/22916 26 Vaccinia_virus R-HSA-75153 Apoptotic execution phase 30/3478 52/10654 1.7003823513908844e-4 3.6122425031010006e-4 1.46329109188891e-4 4000/1828/2934/3837/1499/5747/10059/63967/1829/841/100506658/7082/5339/5317/3146/10134/329/1832/999/836/324/4137/1830/5580/6709/6093/839/840/7431/3148 30 Vaccinia_virus R-HSA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 11/3478 13/10654 1.7057087343162847e-4 3.6122425031010006e-4 1.46329109188891e-4 7027/5925/5557/5422/1869/5519/5518/23649/5558/5515/5516 11 Vaccinia_virus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 11/3478 13/10654 1.7057087343162847e-4 3.6122425031010006e-4 1.46329109188891e-4 207/10193/2064/7316/10000/3084/208/9542/6233/7311/7314 11 Vaccinia_virus R-HSA-171007 p38MAPK events 11/3478 13/10654 1.7057087343162847e-4 3.6122425031010006e-4 1.46329109188891e-4 4893/5899/6714/5898/1432/5603/5900/3845/5600/3265/6300 11 Vaccinia_virus R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 12/3478 15/10654 2.2582442158319081e-4 4.7677869495841354e-4 1.9313930793299212e-4 6737/29110/23220/147945/7316/51428/22954/3661/6233/7311/81030/7314 12 Vaccinia_virus R-HSA-5358508 Mismatch Repair 12/3478 15/10654 2.2582442158319081e-4 4.7677869495841354e-4 1.9313930793299212e-4 6118/4436/9156/2956/4292/3978/5111/5395/6119/6117/10714/5424 12 Vaccinia_virus R-HSA-112040 G-protein mediated events 31/3478 55/10654 2.3824872106493333e-4 5.022442597791974e-4 2.034552084076095e-4 3838/5321/5567/2770/2781/5578/5594/5568/5582/112/114/3708/108/5573/2775/113/111/107/346562/5566/5576/2771/5577/5580/1385/196883/115/801/814/109/2773 31 Vaccinia_virus R-HSA-2871809 FCERI mediated Ca+2 mobilization 21/3478 33/10654 2.503237579600499e-4 5.26897271694026e-4 2.1344195007631835e-4 6464/4773/5335/4772/3937/5336/5532/4775/10451/3708/5530/6850/4067/5534/695/6654/2885/7410/7409/3702/801 21 Vaccinia_virus R-HSA-4655427 SUMOylation of DNA methylation proteins 13/3478 17/10654 2.670700292644194e-4 5.604424098957893e-4 2.2703082232525604e-4 1912/1788/8535/1786/6045/80012/1911/7341/84733/57332/7329/648/6015 13 Vaccinia_virus R-HSA-9034015 Signaling by NTRK3 (TRKC) 13/3478 17/10654 2.670700292644194e-4 5.604424098957893e-4 2.2703082232525604e-4 5295/5800/4893/6464/5290/3667/5335/6714/6654/2885/581/3845/3265 13 Vaccinia_virus R-HSA-190872 Transport of connexons to the plasma membrane 14/3478 19/10654 2.9407823681018146e-4 6.145200534913447e-4 2.4893725138581545e-4 84617/51807/10382/7277/10381/7278/112714/7846/113457/347733/10376/10383/84790/7280 14 Vaccinia_virus R-HSA-3000480 Scavenging by Class A Receptors 14/3478 19/10654 2.9407823681018146e-4 6.145200534913447e-4 2.4893725138581545e-4 5648/2512/1282/7184/1284/811/1277/348/338/335/1281/78989/2495/1278 14 Vaccinia_virus R-HSA-170660 Adenylate cyclase activating pathway 9/3478 10/10654 2.9550206182327475e-4 6.145200534913447e-4 2.4893725138581545e-4 112/114/108/113/111/107/196883/115/109 9 Vaccinia_virus R-HSA-2562578 TRIF-mediated programmed cell death 9/3478 10/10654 2.9550206182327475e-4 6.145200534913447e-4 2.4893725138581545e-4 23643/11035/8737/841/7099/929/8772/353376/148022 9 Vaccinia_virus R-HSA-5602498 MyD88 deficiency (TLR2/4) 9/3478 10/10654 2.9550206182327475e-4 6.145200534913447e-4 2.4893725138581545e-4 23643/10333/7099/4615/7096/929/114609/695/7097 9 Vaccinia_virus R-HSA-74749 Signal attenuation 9/3478 10/10654 2.9550206182327475e-4 6.145200534913447e-4 2.4893725138581545e-4 3643/6464/3667/5594/3630/6654/2885/8660/5595 9 Vaccinia_virus R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress 18/3478 27/10654 2.988352683369161e-4 6.195910877943545e-4 2.509914875883648e-4 440/9709/4802/5073/1051/1649/3576/3484/4800/1054/4801/6347/11340/467/8570/23016/54512/167227 18 Vaccinia_virus R-HSA-912526 Interleukin receptor SHC signaling 18/3478 27/10654 2.988352683369161e-4 6.195910877943545e-4 2.509914875883648e-4 5295/5777/6464/5290/5291/3561/3560/3718/8503/3558/3717/3636/6654/2885/3716/9846/5296/3559 18 Vaccinia_virus R-HSA-389513 CTLA4 inhibitory signaling 15/3478 21/10654 3.084741533979312e-4 6.360869120877022e-4 2.5767381656298334e-4 207/5528/6714/5519/4067/10000/2534/208/5527/7525/3932/5518/5781/5515/5516 15 Vaccinia_virus R-HSA-5218921 VEGFR2 mediated cell proliferation 15/3478 21/10654 3.084741533979312e-4 6.360869120877022e-4 2.5767381656298334e-4 5170/5590/4893/5335/5579/7422/5578/3708/5921/6714/5580/3791/3845/3265/801 15 Vaccinia_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 15/3478 21/10654 3.084741533979312e-4 6.360869120877022e-4 2.5767381656298334e-4 4893/4790/5567/5568/5970/5566/1387/4067/2534/2033/5894/30835/3845/3265/5058 15 Vaccinia_virus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 17/3478 25/10654 3.08628451207896e-4 6.360869120877022e-4 2.5767381656298334e-4 5594/5528/5519/5598/1432/466/6195/1385/6196/5518/6197/5600/51231/1846/5595/5515/5516 17 Vaccinia_virus R-HSA-112409 RAF-independent MAPK1/3 activation 16/3478 23/10654 3.125448434396874e-4 6.430026581543268e-4 2.6047533102508546e-4 1844/5604/5594/1852/983/5605/3717/3716/3570/7297/5781/3569/8682/3572/1846/5595 16 Vaccinia_virus R-HSA-2500257 Resolution of Sister Chromatid Cohesion 60/3478 126/10654 3.1291248490687094e-4 6.430026581543268e-4 2.6047533102508546e-4 5905/11130/84617/5903/55869/1783/1058/991/51807/10382/9212/23244/7277/348995/55920/79023/9133/10381/57122/79980/7278/6232/332/112714/1780/5885/5528/5048/891/5501/8655/4085/983/23279/79902/3796/5519/699/7846/113457/347733/22919/8243/9126/10376/51143/5527/701/7514/5518/10383/5347/84790/6396/55746/140735/7280/5515/1778/5516 60 Vaccinia_virus R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 47/3478 94/10654 3.4338157570086976e-4 7.045681219936365e-4 2.854150173077015e-4 10844/115106/4926/22995/84617/22981/7531/10142/11190/203068/51807/7532/1454/10382/7277/10381/7278/112714/5048/8655/9738/983/4957/5566/7846/113457/7283/347733/3320/22919/80097/10376/10540/5577/80254/54930/5518/10383/55835/5347/84790/9662/1453/5108/8481/7280/1778 47 Vaccinia_virus R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 39/3478 75/10654 3.912423959501004e-4 8.015839029451021e-4 3.24715348865468e-4 5295/1839/685/5290/3667/5291/3815/2069/8074/930/2064/2100/1950/4233/6714/2099/8503/2261/5159/2247/29851/5880/3084/145957/2534/391/2264/2066/9542/2885/10718/7409/8660/3932/1956/5296/5781/5156/5879 39 Vaccinia_virus R-HSA-111933 Calmodulin induced events 22/3478 36/10654 4.1267499354131934e-4 8.430012773668544e-4 3.4149320223183236e-4 3838/5567/5578/5568/5582/112/114/108/5573/113/111/107/5566/5576/5577/5580/1385/196883/115/801/814/109 22 Vaccinia_virus R-HSA-111997 CaM pathway 22/3478 36/10654 4.1267499354131934e-4 8.430012773668544e-4 3.4149320223183236e-4 3838/5567/5578/5568/5582/112/114/108/5573/113/111/107/5566/5576/5577/5580/1385/196883/115/801/814/109 22 Vaccinia_virus R-HSA-69618 Mitotic Spindle Checkpoint 54/3478 112/10654 4.17308977897488e-4 8.512119799529025e-4 3.4481929341812433e-4 5905/11130/5903/11065/246184/1783/1058/7321/991/8697/9212/348995/55920/79023/57122/79980/6232/332/1780/8881/5528/5048/5501/8655/4085/23279/51433/79902/3796/5519/699/22919/119504/51143/51529/7324/64682/29945/10393/5527/51434/701/7514/5518/25906/5347/29882/6396/55746/140735/996/5515/1778/5516 54 Vaccinia_virus R-HSA-1474228 Degradation of the extracellular matrix 65/3478 140/10654 4.3690045013935406e-4 8.898634168279491e-4 3.6047668718928126e-4 1310/1286/1287/826/1282/1308/1294/7373/960/1511/5340/1299/91522/256076/823/1284/1991/136227/5045/1305/23385/4318/4312/1277/1280/1289/3912/1307/6696/649/1300/4313/1298/102/3915/1301/84570/1281/1297/1290/1303/999/836/682/2335/2200/1295/1288/6868/2/726/1306/1292/7076/50509/1293/1285/131873/80781/1278/1296/5663/4323/1302/1291 65 Vaccinia_virus R-HSA-210990 PECAM1 interactions 10/3478 12/10654 4.461186982929729e-4 9.046477264066874e-4 3.664656949836704e-4 5777/5335/6714/4067/2534/3690/7525/3685/3932/5781 10 Vaccinia_virus R-HSA-3371511 HSF1 activation 10/3478 12/10654 4.461186982929729e-4 9.046477264066874e-4 3.664656949836704e-4 6118/7531/1915/10013/7415/6119/3320/3326/6117/10728 10 Vaccinia_virus R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 10/3478 12/10654 4.461186982929729e-4 9.046477264066874e-4 3.664656949836704e-4 5295/5290/5291/4067/23533/3717/5294/2057/2056/8660 10 Vaccinia_virus R-HSA-4090294 SUMOylation of intracellular receptors 19/3478 30/10654 5.400152198424655e-4 0.0010934518705874483 4.4294877220072966e-4 7068/5241/5468/51588/6613/5465/9759/8856/2099/7341/2908/9971/6256/7329/367/6612/9063/7421/8554 19 Vaccinia_virus R-HSA-373752 Netrin-1 signaling 28/3478 50/10654 5.445453283153216e-4 0.0011010150068857232 4.4601253936544974e-4 5335/7430/9423/5747/4690/7204/9353/6478/6477/6091/7220/1793/6714/1432/90249/2534/5603/998/8976/1630/116986/5599/5600/3983/5058/6300/5781/5879 28 Vaccinia_virus R-HSA-180336 SHC1 events in EGFR signaling 11/3478 14/10654 5.597197045580529e-4 0.0011251259663467392 4.557796998387323e-4 1839/4893/6464/685/2069/1950/6654/2885/1956/3845/3265 11 Vaccinia_virus R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 11/3478 14/10654 5.597197045580529e-4 0.0011251259663467392 4.557796998387323e-4 6118/4436/9156/4292/3978/5111/5395/6119/6117/10714/5424 11 Vaccinia_virus R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 11/3478 14/10654 5.597197045580529e-4 0.0011251259663467392 4.557796998387323e-4 8841/79718/9611/2874/9612/5566/6907/3065/25942/801/814 11 Vaccinia_virus R-HSA-9005895 Pervasive developmental disorders 11/3478 14/10654 5.597197045580529e-4 0.0011251259663467392 4.557796998387323e-4 8841/79718/9611/2874/9612/5566/6907/3065/25942/801/814 11 Vaccinia_virus R-HSA-1834941 STING mediated induction of host immune responses 12/3478 16/10654 6.338567599398895e-4 0.0012704654305596918 5.146555762784083e-4 6737/29110/7520/23220/147945/6778/5591/51428/3428/3661/197358/2547 12 Vaccinia_virus R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 12/3478 16/10654 6.338567599398895e-4 0.0012704654305596918 5.146555762784083e-4 5295/5170/6464/5290/5291/6850/4067/2534/6654/2885/9846/5296 12 Vaccinia_virus R-HSA-198753 ERK/MAPK targets 15/3478 22/10654 6.769154972453803e-4 0.0013548091960763754 5.488225738238329e-4 5594/5528/5519/5598/1432/6195/6196/5518/6197/5600/51231/1846/5595/5515/5516 15 Vaccinia_virus R-HSA-8876384 Listeria monocytogenes entry into host cells 14/3478 20/10654 6.854599895343756e-4 0.0013699308593147334 5.549482409384403e-4 1499/2060/7316/1500/4233/6714/867/999/9146/6233/2885/7311/10254/7314 14 Vaccinia_virus R-HSA-983231 Factors involved in megakaryocyte development and platelet production 75/3478 168/10654 7.116382319223844e-4 0.00142020021788545 5.753119636199468e-4 3831/1017/3443/84617/25/3441/2624/64837/85440/11311/5868/23186/5567/11127/51807/10019/10382/2625/5568/29127/3798/3832/7277/10381/3449/81928/7278/3444/5573/112714/91768/1793/50808/23303/832/3659/5566/3796/3043/3451/3705/3717/7846/5576/113457/3448/89953/347733/10376/3440/4602/3066/3065/998/7157/7975/23028/5577/3835/55083/147700/3799/10383/60/25942/84790/3452/9493/7465/3456/1020/7280/3446/5879/3445 75 Vaccinia_virus R-HSA-9018519 Estrogen-dependent gene expression 68/3478 150/10654 7.437285107913829e-4 0.0014821064567569285 6.003896951939524e-4 27161/3725/2963/3838/596/5434/5440/7090/5241/9687/5430/5436/2625/57690/27327/5441/192670/200845/5438/5431/5885/5435/865/5469/1655/5433/6667/2099/4609/2962/7391/8850/10524/1387/5437/3320/2033/8243/9126/595/4602/8312/5439/192669/3065/2066/861/23028/23112/10498/3326/1025/2353/10499/23030/1386/6908/4343/904/3276/26523/8202/5432/8648/2288/10728/7528/6387 68 Vaccinia_virus R-HSA-375165 NCAM signaling for neurite out-growth 33/3478 63/10654 9.067661891636849e-4 0.0018036013050823562 7.306247354048229e-4 1286/1287/1282/2674/4893/6711/5747/375790/1299/256076/1284/5594/1280/1289/1298/6714/1281/1297/1290/2534/6654/2885/6709/1385/1292/50509/1293/3845/1285/131873/3265/1291/5595 33 Vaccinia_virus R-HSA-1489509 DAG and IP3 signaling 24/3478 42/10654 9.07660728983684e-4 0.0018036013050823562 7.306247354048229e-4 3838/5335/5567/5578/5568/5582/112/114/3708/108/5573/113/111/107/5566/5576/5577/5580/1385/196883/115/801/814/109 24 Vaccinia_virus R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 30/3478 56/10654 9.48093163553973e-4 0.0018812450308341726 7.620775994182893e-4 5442/8841/79718/3418/23408/23410/200186/5465/2553/9611/5469/23409/54205/64784/1387/6907/6648/6256/10498/1385/10499/1386/6742/3054/801/23373/7019/8648/814/10891 30 Vaccinia_virus R-HSA-8854518 AURKA Activation by TPX2 37/3478 73/10654 0.0010244677646518677 0.002029882480747978 8.222894639853105e-4 115106/22995/22981/7531/10142/11190/203068/7532/1454/22974/10382/3161/7277/5048/8655/9738/983/6790/4957/5566/7846/7283/3320/22919/10540/5577/80254/54930/5518/10383/55835/5347/9662/1453/5108/8481/1778 37 Vaccinia_virus R-HSA-5654732 Negative regulation of FGFR3 signaling 18/3478 29/10654 0.0010682145141848755 0.0021135387173515036 8.56177948963216e-4 5594/8074/7316/673/6714/8569/2261/867/2247/6233/2885/7311/5518/5781/7314/5595/5515/5516 18 Vaccinia_virus R-HSA-174414 Processive synthesis on the C-strand of the telomere 9/3478 11/10654 0.0011505435931172352 0.0022538937432353195 9.130346685498195e-4 6118/2237/1763/3978/5111/6119/6117/10714/5424 9 Vaccinia_virus R-HSA-2025928 Calcineurin activates NFAT 9/3478 11/10654 0.0011505435931172352 0.0022538937432353195 9.130346685498195e-4 4773/4772/5532/4775/5530/5534/2280/5478/801 9 Vaccinia_virus R-HSA-376172 DSCAM interactions 9/3478 11/10654 0.0011505435931172352 0.0022538937432353195 9.130346685498195e-4 9423/1432/5603/1630/5599/5600/5058/6300/5879 9 Vaccinia_virus R-HSA-5655291 Signaling by FGFR4 in disease 9/3478 11/10654 0.0011505435931172352 0.0022538937432353195 9.130346685498195e-4 5295/4893/5290/5335/2264/6654/2885/3845/3265 9 Vaccinia_virus R-HSA-8851805 MET activates RAS signaling 9/3478 11/10654 0.0011505435931172352 0.0022538937432353195 9.130346685498195e-4 4893/6464/10048/4233/6654/2885/57610/3845/3265 9 Vaccinia_virus R-HSA-8875555 MET activates RAP1 and RAC1 9/3478 11/10654 0.0011505435931172352 0.0022538937432353195 9.130346685498195e-4 85440/5908/4233/2889/2885/1398/5906/1399/5879 9 Vaccinia_virus R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 9/3478 11/10654 0.0011505435931172352 0.0022538937432353195 9.130346685498195e-4 6885/23118/7316/10454/7189/6233/7311/7314/257397 9 Vaccinia_virus R-HSA-1296041 Activation of G protein gated Potassium channels 16/3478 25/10654 0.0012673955112308328 0.0024723137789502865 0.0010015149110245128 2788/54331/2550/94235/55970/9568/2792/2793/2785/2783/2784/2782/2786/3759/2790/2787 16 Vaccinia_virus R-HSA-1296059 G protein gated Potassium channels 16/3478 25/10654 0.0012673955112308328 0.0024723137789502865 0.0010015149110245128 2788/54331/2550/94235/55970/9568/2792/2793/2785/2783/2784/2782/2786/3759/2790/2787 16 Vaccinia_virus R-HSA-997272 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits 16/3478 25/10654 0.0012673955112308328 0.0024723137789502865 0.0010015149110245128 2788/54331/2550/94235/55970/9568/2792/2793/2785/2783/2784/2782/2786/3759/2790/2787 16 Vaccinia_virus R-HSA-179812 GRB2 events in EGFR signaling 10/3478 13/10654 0.001364611447830789 0.002650752952658685 0.0010737992200395815 1839/4893/685/2069/1950/6654/2885/1956/3845/3265 10 Vaccinia_virus R-HSA-202670 ERKs are inactivated 10/3478 13/10654 0.001364611447830789 0.002650752952658685 0.0010737992200395815 5594/5528/5519/5598/5518/51231/1846/5595/5515/5516 10 Vaccinia_virus R-HSA-3270619 IRF3-mediated induction of type I IFN 10/3478 13/10654 0.001364611447830789 0.002650752952658685 0.0010737992200395815 29110/7520/23220/147945/5591/51428/3428/3661/197358/2547 10 Vaccinia_virus R-HSA-6784531 tRNA processing in the nucleus 30/3478 57/10654 0.0013828729668283893 0.002682463668147506 0.001086644982042653 23165/5903/55706/7175/9631/10557/10248/348995/79023/57122/23636/10762/23511/53371/283742/23279/4927/9688/79902/9883/5901/8086/23225/1653/9972/8021/6396/129401/55746/8480 30 Vaccinia_virus R-HSA-6807505 RNA polymerase II transcribes snRNA genes 37/3478 74/10654 0.001412151649247359 0.0027354266212693597 0.0011080998587395543 6884/2963/5434/5440/55197/5430/5436/6878/79871/5441/5438/5431/5435/4686/5433/6667/2962/5437/8812/905/64859/5439/6827/1025/6880/6908/51593/80237/79035/904/6829/6882/1022/5432/22916/8178/6877 37 Vaccinia_virus R-HSA-381119 Unfolded Protein Response (UPR) 45/3478 94/10654 0.001463853901971387 0.0028311693635455115 0.0011468844923197853 4000/440/10525/9709/6464/8720/1965/37/4802/5073/7184/7094/811/1051/1649/3576/84447/3484/22872/5611/4800/2081/55738/1054/30827/100137049/10954/10130/8894/3309/7466/4801/6745/6347/11340/2931/467/64061/8570/23016/54512/167227/9820/1968/7709 45 Vaccinia_virus R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 11/3478 15/10654 0.0014779317327389204 0.0028311693635455115 0.0011468844923197853 1499/1452/5528/5519/2932/324/8312/5527/5518/5515/5516 11 Vaccinia_virus R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 11/3478 15/10654 0.0014779317327389204 0.0028311693635455115 0.0011468844923197853 1499/1452/5528/5519/2932/324/8312/5527/5518/5515/5516 11 Vaccinia_virus R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 11/3478 15/10654 0.0014779317327389204 0.0028311693635455115 0.0011468844923197853 1499/1452/5528/5519/2932/324/8312/5527/5518/5515/5516 11 Vaccinia_virus R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 11/3478 15/10654 0.0014779317327389204 0.0028311693635455115 0.0011468844923197853 1499/1452/5528/5519/2932/324/8312/5527/5518/5515/5516 11 Vaccinia_virus R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 11/3478 15/10654 0.0014779317327389204 0.0028311693635455115 0.0011468844923197853 1499/1452/5528/5519/2932/324/8312/5527/5518/5515/5516 11 Vaccinia_virus R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 11/3478 15/10654 0.0014779317327389204 0.0028311693635455115 0.0011468844923197853 1499/1452/5528/5519/2932/324/8312/5527/5518/5515/5516 11 Vaccinia_virus R-HSA-844456 The NLRP3 inflammasome 11/3478 15/10654 0.0014779317327389204 0.0028311693635455115 0.0011468844923197853 834/351/4790/7295/29108/5970/10628/3326/4210/114548/4791 11 Vaccinia_virus R-HSA-180292 GAB1 signalosome 12/3478 17/10654 0.001514144913561023 0.002896534123317703 0.0011733632435708423 5295/1839/685/5290/2069/1950/6714/1445/2885/1956/5781/5829 12 Vaccinia_virus R-HSA-3247509 Chromatin modifying enzymes 113/3478 274/10654 0.0015351866121376108 0.0029286962228796017 0.0011863918577198005 55904/23774/6595/9070/10196/1019/8295/8841/8464/29943/55167/11091/4790/9869/79718/64769/84148/7862/6597/2648/23186/55869/10474/2146/5978/1788/9112/9219/51147/6839/6871/5929/23569/5931/6598/117143/79813/6599/86/7403/11240/83933/9611/2874/84289/5970/11143/9612/29072/6603/1108/5926/2122/27097/84444/8850/5928/80853/10524/1387/27154/56950/57459/3717/6907/8289/54815/2033/23512/6602/595/7994/8473/3066/3065/1107/79084/23028/23135/55693/10498/23133/57504/80854/6881/58508/10499/23030/57634/1386/6880/9575/10419/60/55689/9739/8726/3054/10902/6883/3276/6601/51230/10284/6187/53615/9913/8648/64754/4297/4791/55193/10919 113 Vaccinia_virus R-HSA-4839726 Chromatin organization 113/3478 274/10654 0.0015351866121376108 0.0029286962228796017 0.0011863918577198005 55904/23774/6595/9070/10196/1019/8295/8841/8464/29943/55167/11091/4790/9869/79718/64769/84148/7862/6597/2648/23186/55869/10474/2146/5978/1788/9112/9219/51147/6839/6871/5929/23569/5931/6598/117143/79813/6599/86/7403/11240/83933/9611/2874/84289/5970/11143/9612/29072/6603/1108/5926/2122/27097/84444/8850/5928/80853/10524/1387/27154/56950/57459/3717/6907/8289/54815/2033/23512/6602/595/7994/8473/3066/3065/1107/79084/23028/23135/55693/10498/23133/57504/80854/6881/58508/10499/23030/57634/1386/6880/9575/10419/60/55689/9739/8726/3054/10902/6883/3276/6601/51230/10284/6187/53615/9913/8648/64754/4297/4791/55193/10919 113 Vaccinia_virus R-HSA-2559580 Oxidative Stress Induced Senescence 57/3478 125/10654 0.0016199613670984745 0.003086171242684164 0.001250183752499076 1912/3725/1019/5601/5606/1029/7027/2146/8535/6045/57690/5594/27327/80012/5931/7295/192670/8550/7316/1869/1911/1871/4194/1031/5928/1432/84733/5602/23512/1021/57332/192669/7157/23135/23112/5609/1870/6233/1032/2353/1030/7311/4343/8726/5599/648/5600/23466/4217/26523/3456/6416/5608/7314/6015/5595/4193 57 Vaccinia_virus R-HSA-451326 Activation of kainate receptors upon glutamate binding 19/3478 32/10654 0.0016616682640185193 0.0031612782220681993 0.0012806090004654003 2788/54331/59345/10681/51764/94235/55970/2792/2793/2785/2783/2784/2782/2786/1742/801/2791/2790/2787 19 Vaccinia_virus R-HSA-8856828 Clathrin-mediated endocytosis 65/3478 146/10654 0.00169483544565266 0.003219954859024601 0.0013043784456470548 9318/1173/23396/1839/685/7018/71/5868/10618/1856/4738/2060/1212/2069/409/1080/29978/112574/382/338/6453/7316/1950/920/64708/10094/55738/10980/7037/867/1129/9146/10920/408/9322/10987/185/5878/8976/29979/6233/2885/7474/2873/10097/7311/3575/1759/1213/1956/1211/60/8533/29924/4036/51429/3312/10109/154/10254/50813/3092/7314/51138/4952 65 Vaccinia_virus R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 21/3478 37/10654 0.002110218716404595 0.004003634140027896 0.0016218407726656797 27161/8841/79718/347/57690/27327/192670/348/9611/2874/9612/6907/2033/192669/23028/6256/23112/4343/1071/26523/8648 21 Varicella.zoster_virus R-HSA-5683057 MAPK family signaling cascades 279/4500 294/10654 5.0626637028312686e-86 7.06747852915245e-83 2.824433434211129e-83 2308/5689/374/2118/3725/2674/4893/6711/2250/1437/71/5682/1844/1850/1848/5526/817/84292/7039/27327/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/22866/5605/4609/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/192669/4296/5894/1847/3563/1741/9542/1739/2885/6709/8660/8997/8826/5518/2252/1740/4140/4343/2253/3845/5623/3265/4763/3569/5062/5696/5691/2323/7314/3572/5879/5515/5923/5718/818/10156/1839/3667/8823/8831/2065/5700/3815/122706/5707/5567/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/3337/4902/2260/5528/2902/10125/983/3718/2249/25780/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/1445/5710/8555/896/5719/2906/6233/51332/2266/2246/7514/2251/5154/115727/2243/1843/3570/255324/26523/369/801/200734/7297/5781/4747/10602/1846/805/22821/9462/3562/6464/6712/2904/5747/283455/3674/7010/5568/2322/2675/3315/409/5706/1438/673/2676/8315/221002/2263/4233/5597/84078/5714/64926/5566/6710/5688/5159/5687/5708/3084/5063/5529/816/998/9693/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/5058/5924/7529/5595/25759/5516/8822/5786/27161/815/5684/685/5720/2309/5604/3561/5525/153090/10642/10048/5690/57690/5717/9491/3568/8817/10817/10197/192670/8550/54518/2254/7316/10213/152831/1950/3560/57731/26281/10818/5715/8437/10256/2261/5701/27040/5922/5685/2255/53358/5686/2066/6708/27006/8556/5979/23112/1742/5527/5716/88/5906/5155/9048/4254/399473/808/3559/8202/5693/5721/5245/5156/161742/284 279 Varicella.zoster_virus R-HSA-5684996 MAPK1/MAPK3 signaling 246/4500 255/10654 1.551069813820908e-80 1.0826467300469938e-77 4.326668428026744e-78 5689/374/2674/4893/6711/2250/1437/71/5682/1844/1850/1848/5526/817/84292/7039/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/22866/5605/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/1847/3563/1741/9542/1739/2885/6709/8660/8826/5518/2252/1740/4140/2253/3845/5623/3265/4763/3569/5696/5691/2323/7314/3572/5515/5923/5718/818/10156/1839/3667/8823/8831/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/4902/2260/5528/2902/10125/983/3718/2249/25780/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/1445/5710/5719/2906/6233/51332/2266/2246/2251/5154/115727/2243/1843/3570/255324/369/801/200734/7297/5781/4747/1846/805/22821/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/409/5706/1438/673/2676/8315/221002/2263/4233/84078/5714/64926/6710/5688/5159/5687/5708/3084/5529/816/9693/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/5924/7529/5595/25759/5516/8822/5786/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10817/10197/54518/2254/7316/10213/152831/1950/3560/57731/26281/10818/5715/8437/10256/2261/5701/27040/5922/5685/2255/53358/5686/2066/6708/27006/5979/1742/5527/5716/88/5906/5155/9048/4254/399473/808/3559/5693/5721/5245/5156/161742/284 246 Varicella.zoster_virus R-HSA-9607240 FLT3 Signaling 254/4500 267/10654 5.74804886257145e-79 2.6747587373832477e-76 1.0689354025132874e-76 5295/5689/374/2674/4893/6711/2250/1437/71/5682/1844/5291/1850/1848/5526/817/84292/7039/5908/3082/143471/2064/5705/8452/6776/4684/5709/9978/5695/1852/2668/22866/5605/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/1847/3563/1741/9542/1739/2885/6709/8660/8826/9846/5518/2252/1740/4140/2253/3845/5623/3265/4763/5696/5691/2323/7314/5515/54106/5923/5718/818/10156/1839/5290/3667/8823/8831/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/57761/5921/4902/2260/5528/2902/10125/3718/2249/25780/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/1445/5710/5719/2906/6233/51332/2266/2246/2251/5154/115727/2243/1843/6777/255324/369/801/200734/5781/4747/1846/805/22821/5170/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/409/5706/1438/673/2676/8315/221002/2263/4233/84078/5714/64926/6710/5688/5159/5687/5708/3084/5529/816/9693/208/6654/5704/10718/3716/7311/7450/1956/60/5536/2549/5694/5924/7529/5595/25759/5516/8822/5786/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10817/10197/54518/2254/7316/10213/152831/1950/3560/3055/57731/26281/10818/5715/8437/10256/2261/5701/27040/5922/5685/2255/53358/5686/2066/6708/27006/5979/1742/5527/5716/88/5906/5155/9048/4254/5296/399473/808/3559/5693/5721/5245/5156/161742/284 254 Varicella.zoster_virus R-HSA-5673001 RAF/MAP kinase cascade 240/4500 249/10654 2.6561046657040183e-78 9.269805283307023e-76 3.704567033745079e-76 5689/374/2674/4893/6711/2250/1437/71/5682/1844/1850/1848/5526/817/84292/7039/5908/3082/143471/2064/5705/8452/4684/5709/9978/5695/1852/2668/22866/5605/5037/5711/3558/3717/2244/54756/5683/145957/2534/3690/408/9965/5699/2264/5702/4296/5894/1847/3563/1741/9542/1739/2885/6709/8660/8826/5518/2252/1740/4140/2253/3845/5623/3265/4763/5696/5691/2323/7314/5515/5923/5718/818/10156/1839/3667/8823/8831/2065/5700/3815/122706/5707/8844/7094/1849/1439/5594/2069/8074/23198/7414/5921/4902/2260/5528/2902/10125/3718/2249/25780/6714/9861/2248/5519/64096/3567/2247/5698/5692/5713/2335/1445/5710/5719/2906/6233/51332/2266/2246/2251/5154/115727/2243/1843/255324/369/801/200734/4747/1846/805/22821/9462/3562/6464/6712/2904/5747/283455/3674/7010/2322/2675/409/5706/1438/673/2676/8315/221002/2263/4233/84078/5714/64926/6710/5688/5159/5687/5708/3084/5529/816/9693/6654/5704/10718/3716/7311/7450/1956/60/5536/5694/5924/7529/5595/25759/5516/8822/5786/815/5684/685/5720/5604/3561/5525/153090/10048/5690/5717/9491/3568/8817/10817/10197/54518/2254/7316/10213/152831/1950/3560/57731/26281/10818/5715/8437/10256/2261/5701/27040/5922/5685/2255/53358/5686/2066/6708/27006/5979/1742/5527/5716/88/5906/5155/9048/4254/399473/808/3559/5693/5721/5245/5156/161742/284 240 Varicella.zoster_virus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 235/4500 244/10654 1.9149571948661992e-76 5.346560488066428e-74 2.136689080587549e-74 8449/23165/6633/8683/6431/84271/55696/4904/51639/51585/9128/199746/23450/348995/57122/5431/9092/23511/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/23279/8233/22938/988/23020/23225/6631/3181/5439/1660/9410/6638/57721/9877/9972/8021/3312/10907/10291/55746/26121/10262/7919/53981/6432/10084/8563/6430/51340/56001/6627/6936/83443/11051/80145/9129/9879/10081/8106/51690/27238/55749/5438/85313/10762/54883/22794/9785/11338/1655/9343/29107/3185/4116/6626/11157/285755/1478/24144/79902/9883/51213/10236/10250/4670/26097/51362/10465/55660/25949/23283/2521/1977/3191/10285/6636/23524/10914/57187/6396/129401/79228/8175/2733/84950/3188/84324/56259/5725/1994/10450/7536/4928/2963/6635/5434/5903/220988/6632/10283/55706/7175/24148/154007/7884/23350/5436/10523/6428/27258/10212/6637/55110/5093/55954/84321/6429/57819/10181/4927/2962/10898/10569/23658/6434/9295/84844/10482/51692/10421/11193/8086/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/81929/5440/55599/51691/10946/9631/27339/5430/79869/85437/11325/57703/3184/25804/29894/9589/11017/51503/3178/79023/5441/23636/3183/79622/10594/4686/8189/23398/10713/53371/10978/5546/7307/10772/9688/9984/5437/6629/10189/10949/51729/11066/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/84248/6427/5356/57461/84991/8480/10992/55339/6628 235 Varicella.zoster_virus R-HSA-3700989 Transcriptional Regulation by TP53 317/4500 365/10654 1.422222512475758e-72 3.3090377123602635e-70 1.3224174238809682e-70 6884/6875/834/5563/3725/9134/4436/83990/64769/9156/57060/1763/7531/1459/79370/7486/6874/10971/9997/133383/9212/5982/27327/7295/7533/2810/55367/1460/11200/472/53632/79813/5431/7001/639/5435/5433/1869/28996/84289/1457/6790/25904/29117/4194/1647/5928/1432/1387/4683/56950/51499/2965/84126/5439/192669/1107/8900/6873/5371/2475/672/55571/6881/2967/51616/5518/1386/55835/4513/4343/6117/11198/7159/57472/904/144455/85456/29883/51497/51230/637/64121/83695/7296/7314/5515/1263/27166/23368/23774/6118/2176/3622/7027/2936/7832/51422/7249/404672/898/117584/27244/7534/332/5438/5934/64065/1351/116028/890/10769/983/1643/8797/9656/5519/27154/5458/83860/57459/2821/10000/5985/2877/900/7994/2068/54541/3066/7157/5984/6233/1025/2353/604/63970/839/10419/5325/50484/5600/6883/7936/6829/79733/26523/7874/317/2744/5608/5884/5810/57521/26155/26013/5875/253260/25920/5170/80010/2963/5434/83667/1820/7862/1029/5457/9219/8445/7532/5436/1345/55240/204851/6878/4869/5931/4850/4292/580/11073/891/80196/54971/4331/5366/641/5111/1108/8148/2966/246175/64223/2962/84883/6119/147923/3364/5571/10524/54457/4848/8812/144715/23019/1616/843/6794/54815/94241/1874/10128/25824/905/1111/2071/55215/8626/208/79109/55004/7311/7161/5562/6880/6908/5983/1340/5564/6882/5565/1020/53615/10397/8795/5432/665/7248/6877/7529/5516/1017/27161/27113/9891/6917/5440/27165/5305/8621/902/5883/25946/9540/5430/10111/8793/207/22974/57690/4849/1027/58484/3486/355/6749/545/5441/8794/192670/8550/9337/7316/6872/2539/1026/54205/5933/124446/5395/6879/9150/112858/5876/143686/10848/5437/9099/28984/51755/2033/995/5728/3065/91875/6827/23112/10498/10542/5527/1349/2968/5932/8851/5300/7156/581/1327/3276/5052/138474/133746/1022/8178/10919/4193 317 Varicella.zoster_virus R-HSA-449147 Signaling by Interleukins 372/4500 461/10654 6.044776708963241e-67 1.2055011836732405e-64 4.817641587594764e-65 5295/729230/8454/3605/7124/2308/834/1052/5689/3725/7291/5777/9252/1437/4790/5682/5291/26469/5783/27178/1848/356/3593/9021/8878/6624/5908/3082/5743/3091/941/143471/10538/3383/5705/11009/6097/6349/6657/3576/3313/3662/6776/3688/4985/5709/6175/9978/2920/5695/1435/4792/3936/59307/7133/3606/177/4609/3603/5898/5711/4988/1432/3558/3717/4088/836/5683/2534/5699/3181/5702/4001/3654/3563/2885/85480/8660/282618/6196/3594/1154/50604/9846/6347/5518/1386/6382/7040/3588/6197/4282/7334/3600/3312/1399/3551/55801/3569/5062/5696/5691/51231/4692/7314/3572/3596/5515/3598/5718/54014/10148/8945/5601/1072/3592/5290/3667/6627/5606/90865/64109/9049/3587/7412/5700/122706/5707/27250/1849/29110/1439/5594/4582/23198/6367/4312/9987/8517/6778/7534/6810/332/5528/4313/3565/3934/3976/50615/3185/5970/5443/9261/3718/3627/8809/9861/149233/5519/5598/4208/3567/598/2247/5698/5692/5713/2335/595/6195/5710/3458/10454/7157/5478/5719/6233/7525/6844/7409/2353/604/6809/3932/7076/302/552900/51561/3570/8835/5600/6777/6773/7850/7297/5781/5608/4791/1846/59067/3557/9655/3562/351/6464/3566/6597/5782/6351/7184/9180/3589/6775/50616/3684/3595/821/4318/5706/3726/58480/301/4478/1438/53833/3581/79155/6774/920/6850/1440/5714/6772/8651/5566/8503/1901/3552/2889/5688/79923/5687/4067/3636/5708/5602/29949/57162/5771/998/6648/7189/163702/112744/6654/5704/3716/7311/2939/1270/6888/5293/2185/6655/6356/5008/5694/246778/6416/1234/3586/3554/829/5595/3556/5516/6095/1147/5778/1845/596/5684/2208/5720/6885/2309/5604/4215/3561/3578/207/5292/5451/7422/5690/3553/2625/1230/5717/2919/9491/6500/3568/25930/246330/10197/4615/3597/2357/7316/10213/3560/6352/4314/1441/4205/3055/1026/6348/4793/3146/6647/6364/5715/7132/5701/867/466/6950/23291/5685/3320/5686/4843/9466/6288/2002/942/6285/5609/1398/58985/948/5716/1385/53832/6363/3575/4507/6845/5296/6935/3687/5599/5784/7431/375/3977/3559/3574/3929/3162/1489/57161/1278/4170/5693/3689/5721/3601/5724/5034 372 Varicella.zoster_virus R-HSA-5663202 Diseases of signal transduction 317/4500 377/10654 2.867169748356119e-65 5.003211210881428e-63 1.999473640300978e-63 5295/8454/2308/27123/5689/374/4893/11052/2250/5335/71/79718/5682/5291/892/5526/817/1452/7039/9530/613/182/5908/3082/941/55109/143471/2064/5705/54845/5431/6776/5435/5709/9978/5433/5695/8546/9759/9612/22866/5605/4609/4089/22938/5037/5711/1387/3717/10827/4088/2244/6907/5683/145957/2534/3690/408/9965/5699/6400/8312/11064/5439/2264/5702/4296/5894/6868/9794/9542/2885/2475/8660/79412/8826/9846/5518/2252/6469/1185/4140/7040/2253/3845/388585/3265/4763/5696/7750/5691/7314/5879/5515/5718/818/8805/1839/26127/5290/3667/8823/79885/2065/2648/9734/55750/5700/3815/122706/5707/10956/8844/51564/7094/8322/55534/5594/3280/2069/8074/7249/23198/84441/7414/10533/10013/23164/2260/5438/5528/89780/102/57085/2249/6714/2099/5664/9861/2248/5519/9061/8850/399687/2932/2247/5698/10000/5692/5713/2335/1445/5710/3066/5719/6233/2266/7409/2246/4040/2251/5154/3932/2931/2243/6777/255324/369/801/5781/5663/1523/57670/253260/805/5170/2963/5434/6464/572/283455/3674/5436/4303/409/5706/6199/10046/9208/84447/673/8315/6774/2263/4233/1024/5714/6772/6934/64223/10014/2962/8503/5688/5159/5687/5708/3084/5529/816/4087/208/6654/5704/10718/79109/56829/7048/23493/7311/5293/7450/1956/11160/60/9444/2549/5694/4851/5432/22916/11140/7529/5595/5516/4000/1147/8822/27044/815/5440/5684/22906/8841/685/5720/8087/1487/2309/5604/1499/10018/5525/10142/842/5430/23462/207/5690/27121/5717/1027/9491/6500/8817/5441/10197/54518/2100/2254/4686/7316/10213/152831/1950/9611/1026/26281/10818/7415/5715/80853/10256/2261/5701/867/5437/5685/2255/3164/3320/5686/2033/54894/55294/5728/3065/2066/27006/942/5527/1488/5716/1385/5906/5155/54567/4254/5296/808/3516/9715/5693/5721/5245/5156/4193 317 Varicella.zoster_virus R-HSA-72172 mRNA Splicing 186/4500 191/10654 3.6248845928065603e-63 5.622598768397731e-61 2.2470044844297983e-61 8449/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/5431/9092/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/8233/22938/988/23020/6631/3181/5439/1660/9410/6638/3312/10907/10291/26121/10262/53981/6432/10084/6430/51340/6627/6936/83443/11051/9129/9879/10081/8106/51690/27238/55749/5438/85313/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/10236/10250/4670/51362/10465/55660/25949/23283/2521/3191/10285/6636/23524/10914/8175/84950/3188/56259/5725/1994/10450/7536/2963/6635/5434/220988/6632/10283/24148/154007/23350/5436/10523/6428/27258/6637/55110/5093/55954/6429/57819/10181/2962/10898/10569/23658/6434/9295/84844/51692/10421/11193/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/55599/51691/10946/27339/5430/79869/85437/11325/57703/3184/25804/29894/11017/51503/3178/5441/3183/79622/10594/4686/8189/23398/10713/10978/5546/7307/10772/5437/6629/10189/10949/51729/11066/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/57461/84991/10992/55339/6628 186 Varicella.zoster_virus R-HSA-5663205 Infectious disease 318/4500 383/10654 8.33506519362221e-63 1.1635751010296604e-60 4.650089002757654e-61 6158/6884/23165/6875/5689/6138/2237/6227/7852/6206/6234/6191/162/6128/5682/6132/6129/6874/1174/811/6224/6146/348995/6154/143471/6202/57122/5705/6169/5431/23511/5435/5709/6175/9978/5433/6218/5695/2960/292/567/6173/23279/5605/6167/5711/23327/29082/23225/5683/2965/2534/6156/27183/5699/6143/5439/5702/6456/6873/3836/6139/30011/2885/163/9972/6881/2967/51616/3921/8021/7040/11198/904/55690/51497/5062/55746/6208/5696/5691/7296/7314/5879/5718/3303/8945/6203/51606/1839/161/402569/5606/6147/5700/122706/5707/2959/8027/10053/6222/2060/8106/23198/404672/9636/10015/91782/5438/6134/3978/10762/6155/1500/4836/926/9397/6714/6231/9861/79902/6142/9883/89853/83860/999/5698/9146/6455/5692/5713/5710/2068/5902/6207/5478/5719/6233/6844/7514/1025/3932/1213/5610/1211/6188/6396/129401/6883/7936/1175/6829/801/5608/8907/200916/6122/2957/805/25920/6230/1173/4928/2963/3838/5434/5903/6857/6194/55706/7175/79643/1938/5436/6136/6878/6125/4869/821/5706/6232/160/6160/920/4233/4331/5714/6193/6210/4927/6229/8148/6205/2966/2962/10898/3840/5688/54457/8812/5687/5708/128866/140801/6235/905/6181/2071/5901/8086/5704/3326/7311/6223/25873/93343/6880/6908/7251/8905/5694/3304/1104/2547/9045/6882/2961/6187/6416/5432/6168/22916/1234/6157/6137/6877/5905/6144/3837/6917/81929/5440/164/5684/9349/8065/4736/5720/902/51121/9631/5604/1499/3159/6217/3843/5430/6152/5690/7520/5717/9491/6500/127833/6749/51065/6141/79023/5441/23636/10197/919/6164/4686/7316/10213/6872/53371/3055/6209/9688/11224/6165/6130/6879/9150/5715/9525/6204/5701/2958/867/6228/5437/5685/3320/5686/6124/6827/5609/2968/5716/6189/808/6135/6201/375/6161/138474/1022/5693/10254/5721/6457/8178/8480/6133/291 318 Varicella.zoster_virus R-HSA-72163 mRNA Splicing - Major Pathway 178/4500 183/10654 3.482069373984862e-60 4.419062587348061e-58 1.7660256155138537e-58 8449/6633/8683/6431/55696/4904/51639/51585/9128/199746/23450/5431/9092/81608/5435/6625/5433/51645/3190/1477/9416/65109/22826/22938/988/23020/6631/3181/5439/1660/9410/6638/3312/10907/10291/26121/10262/53981/6432/10084/6430/51340/6627/6936/83443/11051/9129/9879/8106/51690/27238/55749/5438/85313/54883/22794/9785/11338/1655/9343/3185/4116/6626/11157/285755/1478/24144/10236/10250/4670/51362/10465/55660/25949/23283/2521/3191/10285/6636/23524/10914/8175/84950/3188/56259/5725/1994/10450/7536/2963/6635/5434/220988/6632/10283/24148/23350/5436/10523/6428/27258/6637/55110/5093/6429/57819/10181/2962/10898/10569/23658/6434/9295/84844/51692/10421/11193/9939/1993/1665/5094/8896/6426/5432/22916/1479/11100/10921/22827/23451/5440/51691/10946/27339/5430/79869/11325/57703/3184/25804/29894/11017/51503/3178/5441/3183/10594/4686/8189/23398/10713/10978/5546/7307/10772/5437/6629/10189/10949/51729/57794/27316/3187/10286/56949/53938/6634/51593/9775/3192/9716/6427/5356/57461/84991/10992/55339/6628 178 Varicella.zoster_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 361/4500 473/10654 1.2257916981192867e-53 1.4260043421454367e-51 5.698856140379142e-52 5295/3675/374/5777/627/3643/9252/4893/857/2250/2670/5335/71/5579/5770/5291/26469/1848/5578/7039/3249/1785/5908/3082/51741/2064/535/54845/5431/50617/6696/6776/5435/3688/10312/5433/5753/7423/4734/10413/5605/3910/5898/1432/3717/55824/145957/2534/9475/3690/9965/5439/2264/5603/3630/6456/83737/6868/7072/4145/9542/30011/2885/2475/8660/6093/163/7073/6196/9846/1759/5518/8440/2252/8874/9564/2253/6197/3845/3265/1399/8877/5062/10252/51231/56034/2323/5829/7314/5879/5515/6387/5607/54106/51606/1839/3918/161/5290/3667/5899/8823/23768/2065/3815/5567/8027/10006/9550/1849/2060/9114/5594/2069/8074/284217/9101/57761/5921/6778/2260/5438/348/5528/9306/1500/3185/11059/102/9261/2249/6714/2099/5664/2248/1447/5519/5598/4208/4670/2567/4909/2321/2247/4914/529/10810/10000/9146/6455/2335/64759/6195/3728/8471/1445/84951/3925/6233/7525/7410/5580/2324/7409/2246/23191/3685/2251/5154/57610/3932/1213/3791/1729/1211/29924/5600/6777/255324/1175/6300/528/801/200734/5781/5663/5725/1846/253260/805/25920/5170/4908/1173/2963/5434/5590/6464/80310/85440/653361/5241/2904/6461/5747/5782/7424/5436/10019/10193/5568/2322/7074/3315/2241/10451/4318/382/1277/160/3912/673/527/6774/2263/4233/6772/8651/26052/64223/5566/2962/1003/8503/5795/2889/10163/5159/4067/3084/23767/55845/5063/5771/1111/5796/998/3481/2886/3913/80004/208/6654/5867/10718/79109/5900/7311/2185/387/53834/1956/60/2549/5058/1020/5432/3480/22916/11140/4916/7529/63916/5595/25759/5516/8822/1845/10253/9402/5440/8065/685/26018/558/4915/1495/5604/1499/4690/1299/5430/10048/10273/207/7422/10458/3178/8817/10817/5441/58513/2254/4686/7316/152831/1950/9611/51072/9047/4205/57498/3915/10768/26281/10818/1281/3673/23545/2261/867/5437/466/245972/2255/53358/3320/4846/4803/2002/2066/3914/27006/6285/1742/200958/1398/3187/5774/1385/5228/5906/3479/5155/23163/4254/8851/5296/5581/581/808/10076/7057/1278/10254/6457/51382/5156/161742/2887/2242 361 Varicella.zoster_virus R-HSA-453279 Mitotic G1-G1/S phases 147/4500 149/10654 8.95676309992683e-53 9.309893271221143e-51 3.7205877196103204e-51 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/1031/4998/5711/5928/10926/3717/5683/990/5699/5702/5520/8900/55388/1032/28227/1030/5518/6117/5001/7465/5558/5696/5691/7314/5515/6241/5718/6118/25/23594/7027/5700/5707/7153/898/91768/5934/5557/993/890/1876/983/6714/9861/5519/6502/5698/10000/5692/5713/595/4175/5710/896/5719/6233/7298/23649/1719/1163/1859/4999/4172/26271/1019/5000/8318/1029/54107/4173/5706/286826/891/4331/5714/5111/51053/6119/5688/5687/91750/5427/4067/5708/1874/81620/208/1870/5704/29935/55957/23595/7311/5694/4176/5516/56655/1017/894/5684/5720/4605/902/8317/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5933/5426/4171/1871/5715/5701/5685/5686/1021/3065/5716/1022/5693/5721/7083/132660/1028 147 Varicella.zoster_virus R-HSA-453274 Mitotic G2-G2/M phases 184/4500 198/10654 9.336569183173067e-53 9.309893271221143e-51 3.7205877196103204e-51 114791/10844/8454/5689/440145/5682/7531/11190/203068/54801/51807/63943/347688/79441/143471/10381/5705/5116/5048/5709/9978/1869/5695/8655/6790/9702/5711/5928/7846/7840/5683/5699/11064/5702/5520/8900/28227/5518/55835/29922/23332/7465/5696/93323/5691/7314/5515/5718/8945/4659/5700/122706/5707/1454/23198/993/890/983/9861/79959/5519/5698/5692/5713/80097/5710/10540/7157/85378/5719/6233/7514/54930/54820/1453/27229/9793/4218/5500/84617/2305/11258/22981/8636/51512/7532/84962/55125/10382/121441/7277/5706/9133/286826/9814/653784/23354/728642/891/9738/4331/1639/5714/55722/4957/5566/5688/5687/91750/7283/5708/22919/984/10426/22994/79866/1069/5577/5704/3326/55957/7311/10133/10383/5347/84790/80184/5694/22897/5108/7280/10806/1778/5516/115106/1017/22822/22995/55559/5684/994/5720/4605/902/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/1781/7316/10213/80321/1026/10121/1871/5715/84131/9088/5701/23291/5685/3320/5686/2033/995/10733/4751/27175/80254/5716/9662/55142/1022/8481/5693/5721/132660/55755 184 Varicella.zoster_virus R-HSA-69275 G2/M Transition 182/4500 196/10654 4.7314192084879394e-52 4.387503526769717e-50 1.7534134136540115e-50 114791/10844/8454/5689/440145/5682/7531/11190/203068/54801/51807/63943/347688/79441/143471/10381/5705/5116/5048/5709/9978/5695/8655/6790/9702/5711/5928/7846/7840/5683/5699/11064/5702/5520/8900/28227/5518/55835/29922/23332/7465/5696/93323/5691/7314/5515/5718/8945/4659/5700/122706/5707/1454/23198/993/890/983/9861/79959/5519/5698/5692/5713/80097/5710/10540/7157/85378/5719/6233/7514/54930/54820/1453/27229/9793/4218/5500/84617/2305/11258/22981/8636/51512/7532/84962/55125/10382/121441/7277/5706/9133/286826/9814/653784/23354/728642/891/9738/4331/1639/5714/55722/4957/5566/5688/5687/91750/7283/5708/22919/984/10426/22994/79866/1069/5577/5704/3326/55957/7311/10133/10383/5347/84790/80184/5694/22897/5108/7280/10806/1778/5516/115106/1017/22822/22995/55559/5684/994/5720/4605/902/10142/22974/5690/3161/1063/95681/5717/9491/6500/10197/1781/7316/10213/80321/1026/10121/5715/84131/9088/5701/23291/5685/3320/5686/2033/995/10733/4751/27175/80254/5716/9662/55142/1022/8481/5693/5721/132660/55755 182 Varicella.zoster_virus R-HSA-69242 S Phase 156/4500 161/10654 5.028657337271882e-52 4.387503526769717e-50 1.7534134136540115e-50 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/10274/5925/143471/5705/5709/5422/9978/1869/4174/5753/5695/84515/4609/4998/5711/5928/5683/990/5699/5702/8900/51529/29945/51434/157570/6117/29882/5001/10714/7465/5558/5696/5691/7314/996/5718/6118/23594/7027/5700/122706/5707/23198/898/3978/91768/5934/5557/993/890/51433/9861/2932/6502/5698/10000/5692/5985/5713/119504/595/4175/5710/5984/7324/5719/64682/6233/113130/23649/1163/5424/4999/4172/1019/5000/8318/246184/54107/4173/5706/286826/23047/8881/5885/4331/5425/5714/5111/6119/5688/5687/91750/5427/5708/1874/8243/81620/10393/208/5704/55957/51343/23595/7311/25906/51659/5983/5694/4176/56655/1017/5684/994/5720/902/57804/207/9837/5690/5717/1027/9491/6500/23244/10735/10197/4149/7316/10213/1875/1026/5426/4171/5715/5701/5685/5686/9126/5716/114799/5981/1022/5693/5721/132660 156 Varicella.zoster_virus R-HSA-9006925 Intracellular signaling by second messengers 255/4500 305/10654 1.6552012463086867e-51 1.3592123175570158e-49 5.431929786647703e-50 5295/1912/2308/5689/374/3725/6591/3643/2250/5335/5682/5291/1822/1459/5526/9112/817/6045/5578/7039/27327/80012/3082/1460/941/143471/2064/5705/5709/5695/1457/1911/4734/5711/5928/5683/145957/2534/23512/9965/57332/5699/2444/2264/3630/5702/192669/1107/8975/3654/5371/9542/2885/2475/8660/5518/1386/2252/4343/2253/64121/5696/814/5691/7314/5879/5515/5718/818/1839/5290/3667/8823/90865/2065/23186/5700/3815/122706/5707/5567/2146/51564/5594/2069/84232/8074/7249/23198/112/57761/2260/5573/5528/2249/6714/2099/9861/7101/2248/5519/2932/84733/57459/2247/5698/10000/5692/5713/5710/3066/7157/5719/6233/5580/7409/2246/2251/5154/3932/2931/331/8726/5153/8394/115/255324/26523/7874/801/5781/57521/23608/6015/253260/805/5170/3838/572/23239/9219/8535/4303/5568/5931/5706/6199/2263/4233/5714/10645/1108/2122/64223/5566/84254/10014/8503/5688/5159/5687/5708/3084/54815/5529/816/7189/208/5577/5704/10718/79109/55004/57504/7311/5293/1956/648/2549/5694/23466/53615/5595/3556/5516/1147/8822/27161/815/5684/8841/685/5305/5720/2309/5468/5525/5575/842/5978/10273/207/5690/57690/5717/1027/9491/8817/114/10197/192670/4615/2100/2254/7316/10213/152831/1950/1026/10768/26281/57167/10818/5715/1958/2261/5701/5576/5685/2255/3164/5686/5728/6615/3065/2066/27006/23028/942/5987/23112/10542/5527/5716/1385/5155/4254/5296/5581/808/5693/5721/5137/5156/4193 255 Varicella.zoster_virus R-HSA-69620 Cell Cycle Checkpoints 246/4500 293/10654 2.174381310215831e-50 1.6863535050340554e-48 6.739310493651406e-49 5689/55839/11130/9134/83990/11065/6249/5682/9156/57060/9735/1763/7531/7486/7321/5526/10971/8697/9212/5982/7533/2810/147841/348995/11200/143471/472/57122/5705/1780/23122/5048/5709/4174/5695/57405/8655/84515/23279/4194/4998/5711/2491/4683/10926/5683/990/1060/165918/84126/5699/5702/8900/51529/29945/8924/11004/51434/55388/672/9184/5518/6117/29882/7334/5001/23332/7465/25909/51230/10726/81930/55746/5696/83695/5691/7314/996/5515/5718/6118/79682/10403/23594/25936/5700/122706/5707/51588/51720/3619/23198/63967/898/64105/7534/332/5528/993/116028/890/983/51433/9861/79902/3796/9656/5519/81565/5698/5692/5985/5713/91687/119504/4175/5710/7157/5984/7324/83540/5719/64682/6233/7514/7158/54820/6396/64946/9793/5884/5810/140735/4999/220134/4172/80010/4928/5903/5000/8318/246184/55055/51512/1029/80776/1783/401541/7532/79172/4173/5706/9133/79980/6232/580/8881/11073/891/5501/641/5714/54821/6119/9183/3364/10524/5688/1062/699/5687/144715/5708/22919/5529/51143/1111/10393/5704/23595/7311/25906/5347/84643/5983/5694/4176/7529/1778/5516/1017/5905/81929/5684/5720/54908/55143/5883/5525/25946/1058/991/79019/10111/8317/348235/80152/5690/1063/8379/5717/1027/9491/23421/545/55920/79023/10197/7336/29086/1781/7316/10213/4085/1026/4171/55166/5715/9088/7341/5701/5685/5686/995/79003/5527/5716/701/5932/9025/79184/57551/7156/5693/5721/4193 246 Varicella.zoster_virus R-HSA-1257604 PIP3 activates AKT signaling 227/4500 264/10654 2.748638758847796e-50 2.0195261617639595e-48 8.070795247586327e-49 5295/1912/2308/5689/374/3725/6591/3643/2250/5682/5291/1822/1459/5526/9112/6045/7039/27327/80012/3082/1460/941/143471/2064/5705/5709/5695/1457/1911/4734/5711/5928/5683/145957/2534/23512/9965/57332/5699/2444/2264/3630/5702/192669/1107/8975/3654/5371/9542/2885/2475/8660/5518/1386/2252/4343/2253/64121/5696/5691/7314/5879/5515/5718/1839/5290/3667/8823/90865/2065/23186/5700/3815/122706/5707/2146/51564/5594/2069/84232/8074/7249/23198/57761/2260/5528/2249/6714/2099/9861/7101/2248/5519/2932/84733/57459/2247/5698/10000/5692/5713/5710/3066/7157/5719/6233/7409/2246/2251/5154/3932/2931/331/8726/8394/255324/26523/7874/5781/57521/23608/6015/253260/5170/572/23239/9219/8535/4303/5931/5706/6199/2263/4233/5714/1108/2122/64223/10014/8503/5688/5159/5687/5708/3084/54815/5529/7189/208/5704/10718/79109/55004/57504/7311/5293/1956/648/2549/5694/23466/53615/5595/3556/5516/1147/8822/27161/5684/8841/685/5305/5720/2309/5468/5525/842/5978/10273/207/5690/57690/5717/1027/9491/8817/10197/192670/4615/2100/2254/7316/10213/152831/1950/1026/26281/57167/10818/5715/1958/2261/5701/5685/2255/3164/5686/5728/6615/3065/2066/27006/23028/942/5987/23112/10542/5527/5716/1385/5155/4254/5296/5693/5721/5156/4193 227 Varicella.zoster_virus R-HSA-68877 Mitotic Prometaphase 182/4500 200/10654 1.2074574680206227e-48 8.428053126783946e-47 3.3681708318470005e-47 114791/10844/55839/11130/440145/6249/9735/7531/1459/11190/203068/5526/54801/51807/9212/347688/10274/1460/147841/348995/79441/10381/57122/5116/1780/23122/5048/57405/8655/1457/23279/9702/2491/7846/7840/1060/11064/11004/9184/5518/55835/29922/23332/25909/10726/81930/55746/93323/5515/79682/10403/64151/25936/1454/3619/64105/332/10051/5528/983/79902/3796/79959/5519/81565/80097/91687/23397/10540/85378/83540/7514/54930/54820/113130/6396/1453/27229/64946/9793/140735/220134/84617/4928/5903/11258/22981/55055/8636/80776/1783/401541/7532/55125/10382/79172/121441/7277/9133/79980/6232/23047/9814/653784/5885/23354/891/5501/9738/1639/55722/4957/5566/54821/9183/1062/699/7283/22919/8243/10426/5529/22994/51143/1069/5577/10383/5347/84790/84643/80184/22897/5108/10592/7280/10806/1778/5516/115106/4926/5905/22995/55559/81929/54908/55143/5525/10142/1058/991/79019/348235/80152/1063/8379/95681/23244/23421/55920/79023/10735/1781/80321/4085/55166/10121/84131/3320/79003/9126/9918/10733/4751/5527/27175/80254/701/57551/9662/55142/8481/55755 182 Varicella.zoster_virus R-HSA-5633007 Regulation of TP53 Activity 153/4500 160/10654 1.3515947796406296e-48 8.98488720180152e-47 3.5907029233560593e-47 6884/6875/5563/83990/64769/9156/1763/1459/7486/6874/133383/9212/5982/1460/11200/472/53632/79813/639/28996/84289/1457/6790/29117/4194/5928/1432/4683/56950/84126/1107/8900/6873/5371/2475/672/6881/51616/5518/6117/11198/7159/51230/83695/7314/5515/1263/23368/23774/6118/3622/51422/117584/116028/890/983/5519/27154/5458/83860/57459/10000/5985/900/7994/3066/7157/5984/6233/10419/5600/6883/7874/5608/5884/5810/26155/26013/253260/5170/80010/7862/1029/5457/9219/8445/204851/6878/5931/580/11073/80196/54971/641/1108/8148/64223/6119/3364/5571/10524/54457/144715/1616/6794/54815/94241/1111/8626/208/79109/7311/7161/5562/6880/6908/5983/5564/6882/5565/1020/53615/6877/5516/1017/9891/5305/5883/25946/10111/207/22974/6749/545/8550/7316/6872/6879/112858/10848/9099/2033/3065/91875/5527/5932/8851/5300/7156/138474/133746/10919/4193 153 Varicella.zoster_virus R-HSA-2555396 Mitotic Metaphase and Anaphase 182/4500 202/10654 4.4813215281738145e-47 2.843602206059384e-45 1.1364116793933598e-45 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/5520/51529/4001/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/25936/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/7444/5698/5692/5713/91687/119504/5710/7324/2010/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/26271/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/7443/1781/7316/10213/4085/55166/5715/5701/5685/5686/79003/9126/9232/23592/5527/9700/5716/701/57551/5693/5721 182 Varicella.zoster_virus R-HSA-68882 Mitotic Anaphase 181/4500 201/10654 9.776627322832397e-47 5.933987714206098e-45 2.371447359771703e-45 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/5520/51529/4001/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/25936/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/7444/5698/5692/5713/91687/119504/5710/7324/2010/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7112/7280/1778/5516/4000/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/7443/1781/7316/10213/4085/55166/5715/5701/5685/5686/79003/9126/9232/23592/5527/9700/5716/701/57551/5693/5721 181 Varicella.zoster_virus R-HSA-2467813 Separation of Sister Chromatids 173/4500 190/10654 2.31440445041119e-46 1.3462119219891755e-44 5.3799752575347844e-45 5689/55839/11130/11065/6249/5682/9735/7321/5526/51807/8697/9212/347688/10274/147841/348995/143471/10381/57122/5705/1780/23122/5048/5709/5695/57405/8655/23279/5711/2491/7846/5683/1060/5699/5702/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/5696/5691/7314/996/5515/5718/79682/10403/25936/5700/122706/5707/3619/23198/64105/332/5528/51433/9861/79902/3796/5519/81565/5698/5692/5713/91687/119504/5710/7324/83540/5719/64682/6233/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/246184/55055/80776/1783/401541/10382/79172/7277/5706/79980/6232/23047/8881/5885/5501/5714/54821/9183/5688/1062/699/5687/5708/22919/8243/5529/51143/10393/5704/7311/25906/10383/5347/84790/84643/5694/7280/1778/5516/5905/81929/5684/5720/54908/55143/5525/1058/991/79019/348235/80152/5690/1063/8379/5717/9491/23244/23421/55920/79023/10735/10197/1781/7316/10213/4085/55166/5715/5701/5685/5686/79003/9126/9232/5527/9700/5716/701/57551/5693/5721 173 Varicella.zoster_virus R-HSA-69206 G1/S Transition 129/4500 131/10654 5.217638693312624e-46 2.9135294463457695e-44 1.1643572662971332e-44 8454/5689/9134/5682/5925/5705/5709/5422/1869/4174/5753/5695/84515/4609/4998/5711/5928/10926/5683/990/5699/5702/8900/55388/28227/5518/6117/5001/7465/5558/5696/5691/7314/5515/6241/5718/6118/23594/7027/5700/5707/898/91768/5934/5557/993/890/1876/983/9861/5519/6502/5698/10000/5692/5713/595/4175/5710/5719/6233/7298/23649/1719/1163/4999/4172/26271/1019/5000/8318/54107/4173/5706/286826/891/4331/5714/5111/51053/6119/5688/5687/91750/5427/5708/1874/81620/208/5704/29935/55957/23595/7311/5694/4176/5516/56655/1017/5684/5720/902/8317/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5933/5426/4171/5715/5701/5685/5686/3065/5716/1022/5693/5721/7083/132660 129 Varicella.zoster_virus R-HSA-68886 M Phase 303/4500 395/10654 8.779029661966782e-46 4.713663618502165e-44 1.883759401150767e-44 114791/10844/23165/5689/55839/11130/11065/440145/6249/5579/5682/9735/7531/1459/11190/7321/91754/203068/5526/54801/51807/8697/5578/9212/347688/10274/5861/5925/1460/147841/348995/79441/143471/10381/57122/5705/5116/1780/23122/23511/5048/5709/5695/57405/8655/1457/23279/9702/5711/2491/10112/7846/23225/7840/5683/1060/5699/9663/11064/5702/5520/51529/4001/29945/11004/23133/51434/9184/9972/5518/55844/55835/29922/8021/29882/23332/84930/25909/10726/81930/55746/5696/93323/5691/7314/996/5515/5718/79682/10403/64151/25936/5700/122706/5707/1454/2801/5594/3619/23198/64105/23310/332/10762/10051/5528/983/8548/51433/9861/79902/3796/8615/79959/5519/9883/81565/2029/7444/5698/5692/5713/80097/91687/119504/23397/5710/10540/85378/7324/2010/83540/64900/5719/64682/6233/23175/7514/54930/54820/113130/9493/6396/129401/1453/27229/64946/9793/140735/220134/84617/4928/26271/5903/55706/7175/11258/22981/246184/55055/8636/80776/1783/401541/7532/55125/10382/79172/121441/7277/5706/9133/79980/25836/6232/23047/8881/9814/653784/5885/23354/891/5501/9738/1639/5714/55722/4957/4927/5566/54821/81876/9183/5688/1062/699/5687/7283/5708/22919/8243/10426/5529/22994/51143/1069/8086/10393/79648/5577/5704/7311/25906/10383/5347/54892/84790/84643/80184/5694/22897/6418/5108/7112/10592/7280/10806/29781/5595/1778/5516/4000/115106/4926/5905/22995/55559/81929/5684/5720/54908/55143/9631/5525/10142/1058/991/79019/348235/80152/5690/1063/8379/95681/5717/9491/23244/23421/55920/79023/23636/10735/10197/7443/1781/7316/10213/80321/10776/53371/26003/4085/9688/55166/10121/5715/84131/5701/5685/3320/5686/79003/9126/9918/10733/4751/9232/23592/5527/9700/27175/80254/5716/701/57551/9662/55142/64689/8481/5693/5721/55755/8480 303 Varicella.zoster_virus R-HSA-69306 DNA Replication 124/4500 127/10654 9.694021331535342e-43 5.012168066230865e-41 2.0030531406291356e-41 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/143471/5705/5709/5422/9978/1869/4174/5695/84515/4998/5711/10926/5683/990/5699/5702/8900/51529/29945/51434/55388/6117/29882/5001/10714/5558/5696/5691/7314/996/5718/6118/23594/5700/122706/5707/23198/898/3978/5557/890/51433/9861/6502/5698/5692/5985/5713/119504/4175/5710/5984/7324/5719/64682/6233/23649/5424/4999/4172/5000/8318/246184/54107/4173/5706/8881/5425/5714/5111/51053/6119/5688/5687/5427/5708/81620/10393/1870/5704/29935/51343/23595/7311/25906/51659/5983/5694/4176/56655/1017/5684/5720/57804/8317/9837/5690/5717/9491/6500/10197/7316/10213/5426/4171/1871/5715/5701/5685/5686/5716/5981/5693/5721 124 Varicella.zoster_virus R-HSA-162906 HIV Infection 196/4500 233/10654 1.6294148683401827e-40 8.12379698643891e-39 3.2465784970687855e-39 6884/23165/6875/5689/2237/7852/162/5682/6874/1174/348995/143471/57122/5705/5431/23511/5435/5709/9978/5433/5695/2960/292/567/23279/5711/23327/29082/23225/5683/2965/2534/27183/5699/5439/5702/6873/3836/163/9972/6881/2967/51616/8021/11198/904/55690/51497/5062/55746/5696/5691/7314/5879/5718/8945/51606/161/5700/122706/5707/2959/10053/23198/404672/10015/91782/5438/3978/10762/4836/926/9397/9861/79902/9883/89853/83860/5698/5692/5713/5710/2068/5902/5478/5719/6233/7514/1025/3932/6396/129401/6883/7936/1175/6829/8907/2957/25920/1173/4928/2963/5434/5903/55706/7175/79643/5436/6878/4869/5706/160/920/4331/5714/4927/8148/2966/2962/5688/54457/8812/5687/5708/128866/905/2071/5901/8086/5704/7311/93343/6880/6908/7251/8905/5694/1104/2547/6882/2961/5432/22916/1234/6877/5905/3837/6917/81929/5440/164/5684/8065/5720/902/9631/3159/5430/5690/7520/5717/9491/6500/6749/79023/5441/23636/10197/919/4686/7316/10213/6872/53371/3055/9688/6879/9150/5715/9525/5701/2958/5437/5685/5686/6827/2968/5716/375/138474/1022/5693/5721/8178/8480/291 196 Varicella.zoster_virus R-HSA-69239 Synthesis of DNA 116/4500 119/10654 8.897983236795247e-40 4.283305033988333e-38 1.711771729764603e-38 8454/5689/2237/9134/11065/5682/1763/7321/8697/5982/143471/5705/5709/5422/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/6117/29882/5001/10714/5558/5696/5691/7314/996/5718/6118/23594/5700/122706/5707/23198/898/3978/5557/890/51433/9861/6502/5698/5692/5985/5713/119504/4175/5710/5984/7324/5719/64682/6233/23649/5424/4999/4172/5000/8318/246184/54107/4173/5706/8881/5425/5714/5111/6119/5688/5687/5427/5708/81620/10393/5704/51343/23595/7311/25906/51659/5983/5694/4176/56655/1017/5684/5720/57804/9837/5690/5717/9491/6500/10197/7316/10213/5426/4171/5715/5701/5685/5686/5716/5981/5693/5721 116 Varicella.zoster_virus R-HSA-8856828 Clathrin-mediated endocytosis 136/4500 146/10654 1.6474145477568503e-39 7.665969028895209e-38 3.063613018635547e-38 5869/374/85439/71/8674/5286/4738/7039/1212/23208/1785/29763/950/8871/10094/554/54874/10980/22848/7037/2017/3482/408/9322/10987/6456/185/8976/30011/2885/163/11037/1759/23149/3312/29993/9185/7314/9856/1839/161/7018/25977/5868/10618/10093/8027/1856/9892/8322/2060/2069/1601/6453/55707/8301/1129/9146/6455/4074/10920/26119/6233/90019/7474/6844/1213/2580/1211/29924/4036/255324/1175/85021/10109/6869/1173/6857/84251/23048/9026/29988/409/112574/382/160/338/8218/920/22905/26052/8867/10092/9829/2873/10097/7311/1956/60/274/51429/8673/3092/50618/51138/9318/685/127833/1080/29978/58513/7316/1950/273/64708/10552/26130/3267/3949/867/9341/915/917/6572/115548/5878/10096/143425/3575/6845/551/154/10254/6457/4952/11252 136 Varicella.zoster_virus R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 115/4500 119/10654 3.642896193685976e-38 1.640478414963104e-36 6.555976171998532e-37 5244/84498/79718/9441/34/892/27063/1543/54600/5469/9612/27242/11010/1387/6907/2101/84246/26230/4801/29841/50486/2274/1376/55588/10499/23054/1581/9572/85441/9282/23097/10062/7296/96764/51129/57761/5465/2222/10025/3157/6667/23309/336/3156/6604/80205/9439/3992/4199/123/2168/183/116519/6257/3158/376497/9412/9969/405/133522/54797/55090/4899/1374/9440/6721/51/9862/23179/9442/406/19/335/4800/1024/9968/10001/23389/9971/9443/211/9477/1579/25942/51586/400569/6095/6822/80306/8841/5468/29079/4802/4862/90390/6720/6837/9611/2874/81857/2033/8800/9967/6256/51003/7376/10498/948/112950/196/8202/8648/2180/10891/219541 115 Varicella.zoster_virus R-HSA-1989781 PPARA activates gene expression 113/4500 117/10654 1.963231556047523e-37 8.56459766325732e-36 3.422739226003906e-36 5244/84498/79718/9441/34/892/27063/1543/54600/5469/9612/27242/11010/1387/6907/2101/84246/26230/4801/29841/50486/2274/1376/55588/10499/23054/1581/9572/85441/9282/23097/10062/7296/96764/51129/57761/5465/2222/10025/3157/6667/336/3156/6604/80205/9439/3992/4199/123/2168/183/116519/6257/3158/376497/9412/9969/405/133522/54797/55090/4899/1374/9440/6721/51/9862/23179/9442/406/19/335/4800/1024/9968/10001/23389/9971/9443/211/9477/1579/51586/400569/6095/6822/80306/8841/5468/29079/4802/4862/90390/6720/6837/9611/2874/81857/2033/8800/9967/6256/51003/7376/10498/948/112950/196/8202/8648/2180/10891/219541 113 Varicella.zoster_virus R-HSA-168254 Influenza Infection 138/4500 155/10654 1.5153844928005325e-34 6.410535611968314e-33 2.561894038865334e-33 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/23225/6156/6143/5439/3836/6139/9972/3921/8021/7040/55746/6208/3303/6203/402569/6147/6222/8106/9636/5438/6134/10762/6155/6231/79902/6142/9883/6207/6233/7514/1213/5610/1211/6188/6396/129401/200916/6122/6230/4928/2963/3838/5434/5903/6194/55706/7175/5436/6136/6125/821/6232/6160/6193/6210/4927/6229/6205/2962/10898/3840/140801/6235/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/81929/5440/9349/4736/51121/9631/6217/3843/5430/6152/51065/6141/79023/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 138 Varicella.zoster_virus R-HSA-168255 Influenza Life Cycle 130/4500 144/10654 4.25991983056491e-34 1.7490729657260632e-32 6.989961331886697e-33 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/811/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/23225/6156/6143/5439/3836/6139/9972/3921/8021/55746/6208/3303/6203/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/6207/6233/7514/1213/1211/6188/6396/129401/200916/6122/6230/4928/2963/5434/5903/6194/55706/7175/5436/6136/6125/821/6232/6160/6193/6210/4927/6229/6205/2962/140801/6235/6181/5901/8086/7311/6223/25873/3304/9045/6187/5432/6168/6157/6137/6144/3837/81929/5440/9349/4736/51121/9631/6217/3843/5430/6152/51065/6141/79023/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 130 Varicella.zoster_virus R-HSA-376176 Signaling by ROBO receptors 178/4500 218/10654 1.8146706516252063e-33 7.237943513339394e-32 2.892557730410104e-32 6158/5689/6138/6227/7852/6206/6234/6191/6128/5682/6132/57522/10298/6129/5578/6224/6146/6154/26986/143471/6202/5705/6169/23122/5709/6175/9978/6218/5695/65109/6173/6167/5711/1605/5683/6156/5699/6143/9495/5702/6139/10487/8440/3921/23332/5062/6208/5696/5691/7314/5879/6387/5718/25/6203/8861/6147/5700/122706/5707/5567/6222/23198/27/2935/6134/6091/22794/6155/4116/6714/6231/9861/6142/10486/5698/5692/5713/1981/5710/6207/5719/6233/6188/200916/6122/6230/6194/2107/56924/6136/5568/6125/5706/6232/6160/55110/5714/6193/6210/6229/6205/5566/4650/5688/5687/5708/23767/5063/140801/6235/6181/998/9939/6654/5704/7311/6223/25873/387/6655/23708/5694/5058/9045/6187/6168/22916/6157/6137/10921/6144/55740/23032/5684/9349/4736/5720/51121/4690/6217/6152/5690/5532/5717/9491/51065/6141/10197/6164/4686/7316/10213/5216/6209/11224/6165/6130/5715/6204/5701/6228/5576/5685/5686/7408/6124/8453/5716/23380/6189/9775/6135/6201/6161/5693/5721/6133 178 Varicella.zoster_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 91/4500 92/10654 2.758847407211306e-33 1.0698197167963842e-31 4.2754068006491005e-32 6884/6875/5563/83990/9156/1763/1459/7486/6874/9212/5982/1460/11200/472/53632/28996/1457/6790/4194/1432/4683/84126/8900/6873/672/6881/51616/6117/11198/83695/7314/1263/6118/51422/116028/890/83860/5985/7157/5984/6233/5600/6883/5884/5810/26155/80010/8445/204851/6878/580/11073/641/8148/6119/3364/5571/10524/54457/144715/6794/94241/1111/7311/5562/6880/6908/5983/5564/6882/5565/1020/6877/1017/9891/5883/10111/22974/6749/545/8550/7316/6872/6879/112858/5932/8851/5300/7156/138474/4193 91 Varicella.zoster_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 103/4500 108/10654 1.1023010283645863e-32 4.158951988099899e-31 1.662075519297954e-31 5295/3605/7124/2308/1052/7291/356/3593/9021/6624/3082/5743/3091/10538/3383/6097/6657/3576/3662/3688/4985/7133/3606/4609/4988/3717/6347/7040/3312/3569/4692/3596/3598/3592/7412/4582/6367/4312/6778/332/4313/3565/3934/3976/5443/3718/149233/598/2247/2335/595/7157/2353/604/7076/51561/3570/7297/9655/3566/7184/3684/4318/3726/58480/301/6774/6772/8651/1901/3552/79923/112744/3716/6356/5008/3586/6095/596/2208/2309/3561/207/5292/5451/7422/3553/2625/3597/4314/1026/3320/4843/6288/948/6935/3687/7431/3929/3162/1278/4170/3689 103 Varicella.zoster_virus R-HSA-69052 Switching of origins to a post-replicative state 89/4500 90/10654 1.5484547283156113e-32 5.688533686127878e-31 2.2733545872777678e-31 8454/5689/9134/11065/5682/7321/8697/143471/5705/5709/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/51529/29945/51434/29882/5001/5696/5691/7314/996/5718/23594/5700/122706/5707/23198/898/890/51433/9861/6502/5698/5692/5713/119504/4175/5710/7324/5719/64682/6233/4999/4172/5000/246184/4173/5706/8881/5714/5688/5687/5708/81620/10393/5704/51343/23595/7311/25906/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 89 Varicella.zoster_virus R-HSA-5620912 Anchoring of the basal body to the plasma membrane 95/4500 98/10654 4.76928128701386e-32 1.7071581222234226e-30 6.822453662934807e-31 79867/7531/11190/203068/54801/85302/79441/5116/5048/22832/8655/9702/132320/7846/7840/11064/84902/5518/55835/23332/93323/1454/54806/91147/983/79959/10540/117177/57545/26005/54930/54820/23322/1453/9793/4218/11258/22981/8636/54903/80776/7532/55125/10382/121441/7277/9814/23354/146057/9738/1639/55722/4957/5566/7283/22919/27077/22994/4867/1069/5577/10383/5347/80184/22897/5108/261734/57787/10806/9657/1778/115106/22995/55559/10142/51134/95681/1781/80321/8766/79598/10121/347240/84131/3320/79600/10733/4751/80254/26123/9662/55142/8481/51259/55755 95 Varicella.zoster_virus R-HSA-69618 Mitotic Spindle Checkpoint 105/4500 112/10654 2.145865170302526e-31 7.489069444355815e-30 2.992917211211418e-30 55839/11130/11065/6249/9735/7321/5526/8697/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/51529/29945/11004/51434/9184/5518/29882/23332/25909/10726/81930/55746/996/5515/79682/10403/25936/3619/64105/332/5528/51433/79902/3796/5519/81565/91687/119504/7324/83540/64682/7514/54820/6396/64946/9793/140735/220134/4928/5903/246184/55055/80776/1783/401541/79172/79980/6232/8881/5501/54821/9183/1062/699/22919/5529/51143/10393/25906/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/55166/79003/5527/701/57551 105 Varicella.zoster_virus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 85/4500 86/10654 4.863057827801223e-31 1.616387792288216e-29 6.459700874021676e-30 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 85 Varicella.zoster_virus R-HSA-453276 Regulation of mitotic cell cycle 85/4500 86/10654 4.863057827801223e-31 1.616387792288216e-29 6.459700874021676e-30 8454/5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/8556/4751/9232/5716/701/5693/5721 85 Varicella.zoster_virus R-HSA-168273 Influenza Viral RNA Transcription and Replication 120/4500 134/10654 9.569966477452694e-31 3.0362893642099913e-29 1.2134168021650545e-29 6158/23165/6138/6227/6206/6234/6191/6128/6132/6129/6224/6146/348995/6154/6202/57122/6169/5431/23511/5435/6175/5433/6218/6173/23279/6167/23225/6156/6143/5439/6139/9972/3921/8021/55746/6208/6203/6147/6222/5438/6134/10762/6155/6231/79902/6142/9883/6207/6233/6188/6396/129401/200916/6122/6230/4928/2963/5434/5903/6194/55706/7175/5436/6136/6125/6232/6160/6193/6210/4927/6229/6205/2962/140801/6235/6181/8086/7311/6223/25873/9045/6187/5432/6168/6157/6137/6144/81929/5440/9349/4736/51121/9631/6217/3843/5430/6152/51065/6141/79023/5441/23636/6164/53371/6209/9688/11224/6165/6130/6204/6228/5437/3320/6124/6189/6135/6201/6161/8480/6133 120 Varicella.zoster_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 120/4500 134/10654 9.569966477452694e-31 3.0362893642099913e-29 1.2134168021650545e-29 5295/8454/5689/3725/4893/5335/4790/5682/5291/7321/143471/5705/5530/5709/5695/4792/5711/5683/2534/5699/5702/2885/9846/3845/7334/3265/3551/5062/5696/5691/7314/5879/5718/8945/5601/4773/5290/5700/122706/5707/5336/5594/4214/23198/8517/10125/5970/9861/5588/5698/5692/5713/5710/10454/5719/6233/7410/7409/3702/2353/115727/801/805/5170/6464/2205/4772/3937/4775/10451/5706/2206/6850/5714/5688/5687/4067/5708/5602/695/7189/6654/5704/7311/5694/5058/6416/997/5595/1147/9402/5684/5720/6885/5690/5532/5717/9491/6500/10197/7316/10213/10768/7322/5715/5701/27040/23291/5685/5686/5534/5609/5716/10235/5296/808/5599/5693/5721/2207 120 Varicella.zoster_virus R-HSA-69002 DNA Replication Pre-Initiation 84/4500 85/10654 1.1504767138730464e-30 3.5690344279261616e-29 1.4263220078426072e-29 5689/5682/143471/5705/5709/5422/1869/4174/5695/84515/4998/5711/10926/5683/990/5699/5702/55388/6117/5001/5558/5696/5691/7314/5718/6118/23594/5700/122706/5707/23198/5557/9861/5698/5692/5713/4175/5710/5719/6233/23649/4999/4172/5000/8318/54107/4173/5706/5714/51053/6119/5688/5687/5427/5708/81620/1870/5704/29935/23595/7311/5694/4176/56655/1017/5684/5720/8317/5690/5717/9491/10197/7316/10213/5426/4171/1871/5715/5701/5685/5686/5716/5693/5721 84 Varicella.zoster_virus R-HSA-162909 Host Interactions of HIV factors 116/4500 129/10654 3.7423639620660414e-30 1.135726106748738e-28 4.5387938212700286e-29 23165/5689/162/5682/1174/348995/143471/57122/5705/23511/5709/9978/5695/292/567/23279/5711/23225/5683/2534/5699/5702/3836/163/9972/8021/904/55690/5062/55746/5696/5691/7314/5879/5718/8945/51606/161/5700/122706/5707/10053/23198/10762/926/9861/79902/9883/5698/5692/5713/5710/5902/5478/5719/6233/7514/1025/3932/6396/129401/1175/8907/1173/4928/5903/55706/7175/4869/5706/160/920/5714/4927/5688/5687/5708/5901/8086/5704/7311/8905/5694/1104/5905/3837/81929/164/5684/8065/5720/9631/3159/5690/5717/9491/6500/79023/23636/10197/919/7316/10213/53371/3055/9688/5715/5701/5685/5686/5716/375/5693/5721/8480/291 116 Varicella.zoster_virus R-HSA-6807070 PTEN Regulation 123/4500 140/10654 1.2734219910083714e-29 3.7823342541440137e-28 1.51156473736716e-28 1912/5689/3725/6591/5682/1822/1459/9112/6045/27327/80012/1460/143471/5705/5709/5695/1457/1911/4734/5711/5928/5683/23512/57332/5699/2444/5702/192669/1107/8975/5371/2475/1386/4343/64121/5696/5691/7314/5718/23186/5700/122706/5707/2146/51564/5594/84232/23198/9861/7101/84733/57459/5698/10000/5692/5713/5710/3066/7157/5719/6233/331/8726/26523/7874/57521/23608/6015/9219/8535/5931/5706/5714/1108/2122/64223/10014/5688/5687/5708/54815/208/5704/55004/57504/7311/648/5694/23466/53615/5595/27161/5684/8841/5720/5468/5978/10273/207/5690/57690/5717/9491/10197/192670/7316/10213/57167/5715/1958/5701/5685/5686/5728/6615/3065/23028/5987/23112/10542/5716/5693/5721 123 Varicella.zoster_virus R-HSA-913531 Interferon Signaling 161/4500 199/10654 1.8030972904825059e-29 5.244007953153288e-28 2.095705184113439e-28 80263/3443/23165/201626/5777/5335/960/5770/3107/817/9021/348995/3383/57122/11274/3662/3115/23511/4684/567/4734/6672/23279/3106/3459/3717/23225/1973/3836/5371/4599/684/9972/3133/3429/8021/3127/91543/7334/4938/4261/55746/5696/7314/3445/818/402569/115362/7412/10410/9830/9636/2634/3444/10762/2317/103/3434/3433/79902/23586/9883/3451/3448/1981/10612/3458/3661/7324/1977/3439/51191/6233/5580/81603/5610/10581/3452/4940/6396/3437/129401/6773/7297/5781/3430/3660/3446/8554/3135/3665/4928/3838/5903/10379/55706/7175/3455/2316/2633/4600/3123/2209/8638/25820/1982/7706/9470/3122/3394/3663/6772/8651/4927/3659/3840/25939/3440/5771/3454/816/8086/10346/9246/3716/7311/3456/3105/1974/5595/3460/815/3837/81929/3441/6737/51447/9631/4281/54739/79023/2537/23636/3449/7316/53371/8519/3664/9688/6041/1958/4939/7341/6059/3669/3134/5300/9775/5495/5724/8480 161 Varicella.zoster_virus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 143/4500 171/10654 2.9347200093064574e-29 8.360957414269008e-28 3.3413568312189533e-28 6158/5689/6138/6227/6206/6234/6191/6128/5682/6132/6129/6224/6146/6154/26986/143471/6202/5705/6169/5709/6175/9978/6218/5695/65109/6173/6167/5711/1605/5683/6156/5699/6143/5702/6139/3921/6208/5696/5691/7314/5718/6203/8861/6147/5700/122706/5707/6222/23198/2935/6134/6091/22794/6155/4116/6231/9861/6142/5698/5692/5713/1981/5710/6207/5719/6233/6188/200916/6122/6230/6194/2107/6136/6125/5706/6232/6160/55110/5714/6193/6210/6229/6205/5688/5687/5708/140801/6235/6181/9939/5704/7311/6223/25873/23708/5694/9045/6187/6168/22916/6157/6137/10921/6144/23032/5684/9349/4736/5720/51121/6217/6152/5690/5717/9491/51065/6141/10197/6164/4686/7316/10213/6209/11224/6165/6130/5715/6204/5701/6228/5685/5686/6124/8453/5716/6189/9775/6135/6201/6161/5693/5721/6133 143 Varicella.zoster_virus R-HSA-2262752 Cellular responses to stress 321/4500 479/10654 4.361065321374214e-29 1.2176094377276806e-27 4.8660307796385985e-28 1912/23165/5689/3725/9134/11065/573/4790/5682/7531/1915/11133/7321/51807/817/6045/8697/9530/347688/23677/27327/80012/7295/5925/3091/348995/143471/472/10381/57122/5705/79813/3576/3313/1780/7001/23511/10312/5709/9978/2114/1869/5695/3305/8655/1911/832/23279/4194/1031/5711/5928/1432/1387/4683/7846/23225/5683/3309/23512/57332/5699/7428/5702/192669/9531/8900/51529/4001/29945/8091/8131/2056/51434/2475/1032/3306/1030/6196/9972/23411/8021/4343/6117/10587/6197/29882/3312/4217/3569/64121/55746/5696/5691/7296/7314/51164/996/51182/5718/818/3303/7014/6118/51606/5601/5606/7027/5700/122706/5707/2146/9550/2936/9114/5594/3308/23198/898/10049/10013/27244/3337/10762/847/7323/890/5970/9261/6667/51433/9861/79902/5598/9883/2932/84733/529/5698/5692/5713/2877/119504/6195/5710/3301/10540/7157/7324/5719/64682/6233/2353/538/8726/6396/129401/5600/26523/528/405/5608/3297/57521/140735/768/6015/84617/4928/1019/5903/83667/55706/7175/653361/5241/11258/9448/246184/112399/1029/1783/8535/84962/10382/5931/10294/830/7013/7277/1051/1410/50488/5706/10671/8881/527/6774/1639/5714/4927/64223/6119/3552/10370/10524/5688/5687/57805/3310/2908/5708/5602/7266/25824/51143/816/6648/8086/10393/1870/5704/3326/55004/51343/7311/367/25906/2034/57634/10383/84790/55662/648/5694/3304/23466/3456/2113/6416/10641/7280/10728/829/23523/5595/1778/1017/815/25913/81929/5684/5720/9631/3159/7290/10111/7422/5690/57690/5717/1027/9491/545/79023/23636/10197/192670/10808/3490/8550/29855/1781/7316/10213/10935/53371/1026/9532/54205/9588/9688/10121/7415/1871/6647/7322/5715/5701/112398/245972/144577/5685/3320/5686/2033/1021/6767/25842/8453/23135/10963/22824/23112/5609/10542/5716/9529/5599/54583/5052/5693/5721/2288/5034/8480/10919/51382/2950/4193/23043 321 Varicella.zoster_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 83/4500 85/10654 6.789807643546918e-29 1.85854342556696e-27 7.427446957853183e-28 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/91768/5934/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/1163/1019/5706/286826/4331/5714/5688/5687/91750/5708/1874/208/5704/55957/51343/7311/5694/1017/5684/994/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5715/5701/5685/5686/5716/1022/5693/5721/132660 83 Varicella.zoster_virus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 79/4500 80/10654 8.490754667647891e-29 2.2794410607762416e-27 9.109514117112111e-28 8454/5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/8945/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/26271/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/1017/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 79 Varicella.zoster_virus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 85/4500 88/10654 2.139073429403161e-28 5.634238693295873e-27 2.251656241477012e-27 8454/7531/11190/203068/54801/79441/5116/5048/8655/6790/9702/7846/7840/11064/5518/55835/23332/93323/7314/8945/4659/1454/983/79959/10540/6233/54930/54820/1453/9793/4218/5500/11258/22981/8636/7532/84962/55125/10382/121441/7277/9133/9814/23354/891/9738/1639/55722/4957/5566/7283/22919/22994/79866/1069/5577/7311/10133/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/6500/1781/7316/80321/10121/84131/23291/3320/10733/4751/80254/9662/55142/8481/55755 85 Varicella.zoster_virus R-HSA-69202 Cyclin E associated events during G1/S transition 81/4500 83/10654 3.705757169705873e-28 9.580068535017404e-27 3.8285600388774135e-27 8454/5689/9134/5682/5925/5705/5709/1869/5753/5695/4609/5711/5928/5683/5699/5702/8900/7465/5696/5691/7314/5718/7027/5700/5707/898/91768/5934/993/890/9861/6502/5698/10000/5692/5713/595/5710/5719/6233/1163/1019/5706/286826/4331/5714/5688/5687/91750/5708/1874/208/5704/55957/7311/5694/1017/5684/5720/902/207/5690/5717/1027/9491/6500/10197/4149/7316/10213/1875/1026/5715/5701/5685/5686/5716/1022/5693/5721/132660 81 Varicella.zoster_virus R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 98/4500 106/10654 4.790485133220352e-28 1.2159122265410203e-26 4.859248077716339e-27 374/85439/8674/4738/7039/1212/23208/950/554/10980/22848/7037/3482/408/10987/6456/185/30011/2885/163/11037/23149/9185/7314/9856/1839/161/7018/25977/10618/8027/1856/9892/8322/2060/2069/1601/6453/55707/8301/1129/9146/6455/4074/10920/26119/6233/90019/7474/6844/1213/1211/29924/4036/255324/1175/85021/6869/1173/6857/84251/29988/409/160/338/8218/920/22905/2873/7311/1956/8673/50618/51138/9318/685/127833/1080/29978/58513/7316/1950/64708/3267/3949/867/9341/915/917/6572/115548/143425/3575/6845/551/154/10254/6457 98 Varicella.zoster_virus R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 80/4500 82/10654 8.651957667587633e-28 2.1189706849039186e-26 8.468213414259365e-27 114791/10844/440145/7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/1454/983/79959/80097/10540/85378/54930/54820/1453/27229/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/728642/9738/1639/55722/4957/5566/7283/22919/984/10426/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 80 Varicella.zoster_virus R-HSA-380287 Centrosome maturation 80/4500 82/10654 8.651957667587633e-28 2.1189706849039186e-26 8.468213414259365e-27 114791/10844/440145/7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/1454/983/79959/80097/10540/85378/54930/54820/1453/27229/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/728642/9738/1639/55722/4957/5566/7283/22919/984/10426/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 80 Varicella.zoster_virus R-HSA-5357801 Programmed Cell Death 147/4500 181/10654 2.426006356993453e-27 5.83914633510838e-26 2.3335451346760983e-26 5689/2339/5682/4976/7531/55075/356/10971/10059/7533/2810/143471/5705/5709/1869/5695/8655/660/5711/836/5683/5699/9414/5702/90427/4001/3836/6709/6093/840/7159/26060/637/5062/5696/5691/7314/578/23368/5718/2934/22985/219699/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/100506658/7082/5339/4836/8797/9861/10134/999/5588/598/5698/10000/5692/708/5713/5710/7157/5719/6233/5580/1613/839/8772/331/8717/317/140735/1828/5747/1029/572/7532/330/118/5706/1829/6774/5366/5714/5688/5687/1832/5708/8837/8626/197259/208/5704/7311/7161/5694/8795/3148/7529/5595/4000/5533/27113/3837/596/5684/5720/7186/51765/1499/10018/842/207/5690/5717/9491/355/10197/7099/7316/10213/54205/3146/5715/23604/5701/329/5685/5686/5534/4137/5716/581/5599/7431/5693/5721/6304 147 Varicella.zoster_virus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 75/4500 76/10654 2.637428997989292e-27 6.240425222361105e-26 2.4939114521575823e-26 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 75 Varicella.zoster_virus R-HSA-109581 Apoptosis 145/4500 178/10654 2.9968630430507386e-27 6.972701346831385e-26 2.7865568645910383e-26 5689/2339/5682/4976/7531/55075/356/10971/10059/7533/2810/143471/5705/5709/1869/5695/8655/660/5711/836/5683/5699/9414/5702/90427/4001/3836/6709/6093/840/7159/26060/637/5062/5696/5691/7314/578/23368/5718/2934/22985/219699/1612/7027/5700/122706/5707/8737/5594/23198/63967/841/7534/100506658/7082/5339/4836/8797/9861/10134/999/5588/598/5698/10000/5692/708/5713/5710/7157/5719/6233/5580/1613/839/8772/331/8717/317/140735/1828/5747/1029/572/7532/118/5706/1829/6774/5366/5714/5688/5687/1832/5708/8837/8626/208/5704/7311/7161/5694/8795/3148/7529/5595/4000/5533/27113/3837/596/5684/5720/7186/51765/1499/10018/842/207/5690/5717/9491/355/10197/7099/7316/10213/54205/3146/5715/23604/5701/329/5685/5686/5534/4137/5716/581/5599/7431/5693/5721/6304 145 Varicella.zoster_virus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 74/4500 75/10654 6.221811597399218e-27 1.4238768836015258e-25 5.6903540062495e-26 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/891/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/9232/5716/701/5693/5721 74 Varicella.zoster_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 147/4500 182/10654 7.414188003971597e-27 1.6693881376684434e-25 6.671510428021981e-26 1912/23165/7068/7486/9112/6045/9212/80012/10274/348995/6613/57122/7181/23511/4929/28996/54780/4792/3190/9759/9612/8856/1911/6790/6672/23279/1387/23225/23512/165918/57332/7022/7067/7428/1107/5371/8924/4152/672/115426/9972/10499/6612/5914/8021/6117/11315/55746/7421/4286/10062/79677/7150/6670/3622/1788/51564/51588/3619/7153/51602/2516/8517/332/10762/5465/1655/5970/2099/79902/9656/9883/84733/3066/7157/7158/10155/9063/7155/7690/6396/129401/9189/4791/6015/8554/7020/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/5111/4927/10521/1616/2908/8243/142/9971/1069/8086/7329/367/25942/648/6095/23468/5905/81929/1487/55143/9631/5468/7021/8204/3090/79023/23636/10735/3183/53371/6996/9688/7341/10401/2033/9126/3065/23314/6256/5987/7376/6294/8648/6304/8480/10891/7508/4193 147 Varicella.zoster_virus R-HSA-72613 Eukaryotic Translation Initiation 106/4500 119/10654 7.903120847196015e-27 1.7238682347946307e-25 6.889233633246527e-26 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/6156/6143/1973/6139/3921/8665/6208/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/8894/1981/6207/1977/6233/51386/6188/200916/6122/1968/6230/6194/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/8893/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/8891/51121/6217/6152/51065/6141/10480/1967/6164/8661/9669/6209/11224/6165/6130/8890/6204/6228/6124/3646/6189/6135/6201/6161/8892/6133 106 Varicella.zoster_virus R-HSA-72737 Cap-dependent Translation Initiation 106/4500 119/10654 7.903120847196015e-27 1.7238682347946307e-25 6.889233633246527e-26 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/6156/6143/1973/6139/3921/8665/6208/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/8894/1981/6207/1977/6233/51386/6188/200916/6122/1968/6230/6194/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/8893/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/8891/51121/6217/6152/51065/6141/10480/1967/6164/8661/9669/6209/11224/6165/6130/8890/6204/6228/6124/3646/6189/6135/6201/6161/8892/6133 106 Varicella.zoster_virus R-HSA-8953897 Cellular responses to external stimuli 323/4500 493/10654 1.3638160492734724e-26 2.9290572381319496e-25 1.1705627629391748e-25 1912/23165/5689/3725/9134/11065/573/4790/5682/7531/1915/11133/7321/51807/817/6045/8697/9530/347688/23677/27327/80012/7295/5925/3091/348995/143471/472/10381/57122/5705/79813/3576/3313/1780/7001/23511/10312/5709/9978/2114/1869/5695/3305/8655/1911/832/23279/4194/1031/4493/5711/5928/1432/1387/4683/7846/23225/5683/3309/23512/57332/5699/7428/5702/192669/9531/8900/51529/4001/29945/8091/8131/2056/51434/2475/1032/3306/1030/6196/9972/23411/8021/4343/6117/10587/6197/29882/3312/4217/3569/64121/55746/5696/5691/7296/7314/51164/996/51182/5718/818/3303/7014/6118/51606/5601/5606/7027/5700/122706/5707/2146/9550/2936/9114/5594/3308/23198/898/10049/10013/27244/3337/10762/847/7323/1465/890/5970/9261/6667/51433/9861/79902/5598/9883/2932/84733/529/5698/5692/5713/2877/119504/6195/5710/3301/10540/7157/7324/5719/64682/6233/2353/538/8726/6396/129401/5600/26523/528/405/5608/3297/57521/140735/768/6015/84617/4928/1019/5903/83667/55706/7175/653361/5241/11258/9448/246184/112399/1029/1783/8535/84962/10382/5931/10294/830/7013/7277/1051/1410/50488/5706/10671/8881/527/6774/1639/5714/4927/64223/6119/3552/10370/10524/5688/5687/57805/3310/2908/5708/5602/7266/25824/51143/816/6648/8086/10393/1870/5704/3326/55004/51343/7311/367/25906/2034/57634/10383/84790/55662/648/5694/3304/23466/3456/2113/6416/10641/7280/10728/829/23523/5595/1778/1017/815/25913/81929/5684/5720/9631/3159/7290/10111/7422/5690/57690/5717/1027/9491/545/79023/23636/10197/192670/10808/3490/8550/29855/1781/7316/10213/10935/53371/1026/9532/54205/9588/9688/10121/7415/1871/6647/7322/5715/5701/112398/245972/144577/5685/3320/5686/2033/1021/6767/25842/8453/23135/10963/22824/23112/5609/10542/5716/9529/5599/54583/5052/5693/5721/2288/5034/8480/10919/51382/2950/4193/23043 323 Varicella.zoster_virus R-HSA-8878166 Transcriptional regulation by RUNX2 107/4500 121/10654 1.874444613310231e-26 3.9647343639107307e-25 1.5844587640421411e-25 8454/8493/5689/7291/5682/5925/143471/5705/5709/9978/5695/9759/10413/4089/5711/5683/2101/1749/5699/5702/5696/5691/7314/5718/25/6662/5700/122706/5707/5594/3280/23198/100526737/10013/2737/865/11059/983/6714/2099/9861/2932/6502/5698/10000/5692/5713/595/5710/5719/6233/7525/10432/133522/117581/1019/3958/5706/3678/1277/891/579/5714/6772/5688/5687/2908/5708/4488/208/5704/23493/7311/367/860/1750/5694/5595/57154/5684/8841/5720/23462/10273/207/5690/5717/9491/6500/4086/10197/7316/10213/4094/1026/5715/5701/5685/5686/55294/23314/861/5716/581/5693/5721/10891 107 Varicella.zoster_virus R-HSA-2990846 SUMOylation 150/4500 188/10654 2.618959101478589e-26 5.456816277110612e-25 2.18075149062632e-25 1912/10054/23165/7068/7486/9112/6045/9212/80012/10274/348995/6613/57122/7181/23511/4929/28996/54780/4792/3190/9759/9612/8856/1911/6790/6672/23279/1387/23225/10055/23512/165918/57332/7022/7067/7428/1107/5371/8924/4152/672/115426/9972/10499/6612/5914/8021/6117/11315/55746/7421/4286/10062/79677/7150/6670/3622/1788/51564/51588/3619/7153/51602/2516/8517/332/10762/5465/1655/5970/2099/79902/9656/9883/84733/3066/7157/7158/10155/9063/7155/7690/6396/129401/9189/4791/6015/8554/7020/4928/5903/55706/7175/5241/1029/8535/1786/4869/5885/10210/641/5111/4927/10521/1616/2908/8243/142/9971/1069/8086/7329/367/25942/648/6095/23468/5905/81929/29843/1487/55143/9631/5468/7021/8204/3090/79023/23636/10735/3183/53371/6996/9688/7341/10401/2033/9126/3065/23314/6256/5987/7376/6294/8648/6304/8480/10891/7508/4193 150 Varicella.zoster_virus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72/4500 73/10654 3.459303103292109e-26 7.10174578264086e-25 2.838127933041514e-25 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/4751/5716/701/5693/5721 72 Varicella.zoster_virus R-HSA-2500257 Resolution of Sister Chromatid Cohesion 110/4500 126/10654 4.4078655216722714e-26 8.917942417760132e-25 3.5639492394909294e-25 55839/11130/6249/9735/5526/51807/9212/347688/10274/147841/348995/10381/57122/1780/23122/5048/57405/8655/23279/2491/7846/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/983/79902/3796/5519/81565/91687/83540/7514/54820/113130/6396/64946/9793/140735/220134/84617/4928/5903/55055/80776/1783/401541/10382/79172/7277/9133/79980/6232/23047/5885/891/5501/54821/9183/1062/699/22919/8243/5529/51143/10383/5347/84790/84643/7280/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23244/23421/55920/79023/10735/1781/4085/55166/79003/9126/5527/701/57551 110 Varicella.zoster_virus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 71/4500 72/10654 8.15305119883788e-26 1.5807860379969002e-24 6.317422712549821e-25 5689/11065/5682/7321/8697/9212/143471/5705/5709/5695/6790/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/6502/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5347/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 71 Varicella.zoster_virus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 71/4500 72/10654 8.15305119883788e-26 1.5807860379969002e-24 6.317422712549821e-25 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/8900/51529/29945/51434/9184/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/890/983/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/4085/5715/5701/5685/5686/5716/701/5693/5721 71 Varicella.zoster_virus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 71/4500 72/10654 8.15305119883788e-26 1.5807860379969002e-24 6.317422712549821e-25 5689/9134/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/990/5699/5702/8900/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/898/890/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/1017/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 71 Varicella.zoster_virus R-HSA-141424 Amplification of signal from the kinetochores 89/4500 96/10654 8.399959055675354e-26 1.5846409245571341e-24 6.332828306554677e-25 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/79902/3796/5519/81565/91687/83540/7514/54820/6396/64946/9793/140735/220134/4928/5903/55055/80776/1783/401541/79172/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/55166/79003/5527/701/57551 89 Varicella.zoster_virus R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 89/4500 96/10654 8.399959055675354e-26 1.5846409245571341e-24 6.332828306554677e-25 55839/11130/6249/9735/5526/9212/147841/348995/57122/1780/23122/5048/57405/8655/23279/2491/1060/11004/9184/5518/23332/25909/10726/81930/55746/5515/79682/10403/25936/3619/64105/332/5528/79902/3796/5519/81565/91687/83540/7514/54820/6396/64946/9793/140735/220134/4928/5903/55055/80776/1783/401541/79172/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/5347/84643/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/55166/79003/5527/701/57551 89 Varicella.zoster_virus R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 100/4500 112/10654 1.450283164903153e-25 2.699460397606402e-24 1.0788071261735736e-24 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/8668/6224/6146/6154/8662/6202/6169/6175/6218/6173/6167/6156/6143/1973/6139/3921/8665/6208/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/8894/1981/6207/1977/6233/51386/6188/200916/6122/1968/6230/6194/1983/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6217/6152/51065/6141/10480/6164/8661/9669/6209/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 100 Varicella.zoster_virus R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 80/4500 84/10654 1.7330827719314502e-25 3.1420565579432527e-24 1.2556853986653025e-24 7124/1052/84498/4790/79718/9441/892/5469/9612/1387/6907/84246/4023/55588/10499/23054/7040/85441/9282/23097/96764/51129/7471/3952/5465/10025/5970/6604/80205/9439/896/9370/1879/9412/9969/54797/5105/55090/1019/9440/6721/9862/1051/9442/1050/1024/9314/9968/5346/10001/23389/9443/9477/2167/51586/400569/6517/80306/8841/5468/29079/90390/6720/6837/688/9611/81857/2033/9967/6256/51003/10498/948/112950/27332/8202/8648/1959/10891/219541 80 Varicella.zoster_virus R-HSA-72202 Transport of Mature Transcript to Cytoplasm 80/4500 84/10654 1.7330827719314502e-25 3.1420565579432527e-24 1.2556853986653025e-24 23165/8683/6431/84271/199746/348995/57122/23511/81608/65109/23279/23225/9877/9972/8021/55746/7919/53981/6432/8563/6430/56001/80145/10762/22794/9785/11338/29107/4116/79902/9883/51213/10250/26097/51362/1977/57187/6396/129401/79228/2733/84324/4928/5903/55706/7175/7884/6428/10212/55110/84321/6429/4927/10898/10569/9295/10482/51692/8086/9939/6426/22916/10921/81929/9631/29894/79023/23636/4686/8189/53371/7307/9688/9984/10189/9775/84248/6427/8480/55339 80 Varicella.zoster_virus R-HSA-6802957 Oncogenic MAPK signaling 70/4500 71/10654 1.9209347306944592e-25 3.394461878543626e-24 1.3565561722425896e-24 4893/71/817/5908/55109/54845/8546/22866/5605/5037/3717/10827/2244/3690/408/4296/5894/8826/1185/4140/3845/3265/4763/818/8805/55750/8844/7094/5594/7414/10533/23164/57085/6714/9061/2335/1445/2266/2243/369/801/57670/805/283455/3674/409/673/8315/816/56829/7450/60/9444/7529/5595/4000/27044/815/22906/8087/5604/10018/10142/54518/80853/10256/5906/808/9715/5245 70 Varicella.zoster_virus R-HSA-68949 Orc1 removal from chromatin 70/4500 71/10654 1.9209347306944592e-25 3.394461878543626e-24 1.3565561722425896e-24 8454/5689/5682/143471/5705/5709/9978/4174/5695/84515/4998/5711/5683/990/5699/5702/8900/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/890/9861/6502/5698/5692/5713/4175/5710/5719/6233/4999/4172/5000/4173/5706/5714/5688/5687/5708/81620/5704/23595/7311/5694/4176/1017/5684/5720/5690/5717/9491/6500/10197/7316/10213/4171/5715/5701/5685/5686/5716/5693/5721 70 Varicella.zoster_virus R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 99/4500 111/10654 3.1049394677360057e-25 5.41811937119933e-24 2.165286734079057e-24 6158/6138/6227/6206/1965/6234/27335/6191/6128/6132/6129/8668/6224/6146/6154/8662/26986/6202/6169/6175/6218/6173/6167/6156/6143/1973/6139/3921/8665/6208/6203/6147/8666/6222/8667/6134/6155/6231/6142/7458/8663/8894/1981/6207/1977/6233/51386/6188/200916/6122/1968/6230/6194/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/1975/7311/6223/25873/8664/9045/6187/6168/6157/6137/1974/6144/9349/4736/51121/6217/6152/51065/6141/10480/6164/8661/6209/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 99 Varicella.zoster_virus R-HSA-8854518 AURKA Activation by TPX2 71/4500 73/10654 1.747811085907106e-24 3.012276883859654e-23 1.203820501014641e-23 7531/11190/203068/54801/79441/5116/5048/8655/6790/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/22974/3161/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 71 Varicella.zoster_virus R-HSA-2682334 EPH-Ephrin signaling 85/4500 92/10654 2.029380042383281e-24 3.4548957794720247e-23 1.380707859387855e-23 71/2042/1947/1212/2051/2045/10094/2050/285220/79784/2047/2534/9475/1948/4628/8976/6093/163/284656/8997/1759/8440/8874/3265/5062/5879/1072/161/10093/5921/2046/6453/4313/2902/2041/102/6714/5664/1943/2043/7525/1942/7410/1213/1211/1175/10109/5663/1173/2904/5747/7074/1949/10627/1945/10451/4318/160/2049/8218/10092/4067/2044/5063/6386/998/2048/10097/387/60/5058/4629/3984/28964/4627/6383/10398/10552/4637/1946/10096/103910/1944/10095/1969 85 Varicella.zoster_virus R-HSA-5658442 Regulation of RAS by GAPs 67/4500 68/10654 2.507447633295999e-24 4.1671391620014464e-23 1.6653474256226563e-23 5689/4893/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/3845/3265/4763/5696/5691/7314/5718/10156/8831/5700/122706/5707/23198/5921/9861/5698/5692/5713/5710/5719/6233/200734/22821/9462/5706/84078/5714/64926/5688/5687/5708/5704/7311/5694/5684/5720/153090/5690/5717/9491/10197/7316/10213/5715/8437/5701/5922/5685/5686/5716/399473/5693/5721/161742 67 Varicella.zoster_virus R-HSA-68867 Assembly of the pre-replicative complex 67/4500 68/10654 2.507447633295999e-24 4.1671391620014464e-23 1.6653474256226563e-23 5689/5682/143471/5705/5709/1869/4174/5695/84515/4998/5711/5683/990/5699/5702/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/9861/5698/5692/5713/4175/5710/5719/6233/4999/4172/5000/4173/5706/5714/51053/5688/5687/5708/81620/1870/5704/23595/7311/5694/4176/5684/5720/5690/5717/9491/10197/7316/10213/4171/1871/5715/5701/5685/5686/5716/5693/5721 67 Varicella.zoster_virus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 66/4500 67/10654 5.8998907388339856e-24 9.577031943502609e-23 3.827346501324373e-23 5689/11065/5682/7321/8697/143471/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/122706/5707/23198/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/7311/25906/5694/5684/5720/991/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/9232/5716/5693/5721 66 Varicella.zoster_virus R-HSA-6802952 Signaling by BRAF and RAF fusions 66/4500 67/10654 5.8998907388339856e-24 9.577031943502609e-23 3.827346501324373e-23 4893/71/817/5908/55109/54845/8546/22866/5605/5037/3717/10827/2244/3690/408/5894/8826/1185/4140/3845/3265/818/8805/55750/8844/7094/5594/7414/10533/23164/57085/6714/9061/2335/1445/2266/2243/369/801/57670/805/283455/3674/409/673/816/56829/7450/60/9444/7529/5595/4000/27044/815/22906/8087/5604/10018/10142/54518/80853/10256/5906/808/9715 66 Varicella.zoster_virus R-HSA-5688426 Deubiquitination 210/4500 297/10654 8.142731631895986e-24 1.3065808457617006e-22 5.2215943918994224e-23 5689/221937/645836/5682/79594/7419/10474/7321/4738/7375/9817/10445/91833/6478/3091/143471/100287513/5705/11274/55031/8239/5709/5695/4792/9986/11047/4609/392188/4194/4089/100287144/5711/7347/4088/114803/5683/408/55777/64135/5699/8724/8312/100287327/5702/8900/8975/57599/377630/672/6881/51616/7040/728386/7345/3054/1540/100287404/5696/5691/7314/5718/3607/90865/2648/5700/122706/5707/8027/8737/83444/171023/55611/100287364/51720/57646/23198/63967/9101/8517/86/993/890/7417/80124/983/4092/2099/1643/9861/23586/64426/100287441/8850/7128/6502/5698/9146/5692/5713/5710/10454/8473/7157/10869/9958/5719/6233/100287478/9804/55593/93973/10318/23770/8607/7874/100287178/5886/100287238/10600/114785/23326/51651/8237/4303/409/330/5706/4287/27005/7706/580/7416/79155/25862/9738/84132/5714/79589/55288/27430/5688/9097/5687/5708/125476/4087/63891/84749/7189/5704/7048/7311/367/387/60/5694/7528/9960/23358/23032/5684/8295/5720/10617/7186/56957/6885/991/51377/5690/2625/57506/5717/9491/4086/1080/57695/10197/64750/29086/7316/10213/8314/55252/8678/9100/7415/5715/283899/3416/5701/329/9099/5685/54617/5686/2033/221656/5728/5716/79184/78990/5887/9736/5693/154/10254/5721/100287205/4193 210 Varicella.zoster_virus R-HSA-8878159 Transcriptional regulation by RUNX3 87/4500 96/10654 1.806313328697313e-23 2.865469780524374e-22 1.1451507945090624e-22 5689/6046/5682/182/5705/6097/6696/5709/5695/9759/10413/4609/4089/22938/5711/1387/4088/5683/5699/5702/9794/7040/3845/5696/5691/7314/5718/8463/51176/2648/5700/5707/55534/3280/84441/463/865/6714/9861/8850/5698/5692/5713/595/5710/7157/5719/6233/1029/864/5706/10046/5714/6934/5688/5687/5708/5704/7311/5694/4851/3676/57154/5684/5720/2309/1499/10018/5690/5717/9491/10197/64750/7316/10213/1026/5715/5701/5685/5686/2033/861/5716/3516/5693/5721/4193 87 Varicella.zoster_virus R-HSA-9013694 Signaling by NOTCH4 77/4500 82/10654 1.969441450007097e-23 3.089146364280795e-22 1.2345404713231953e-22 8454/5689/5682/182/5705/5709/9978/5695/22938/5711/1387/4088/5683/5699/4853/5702/9794/388585/5696/5691/7314/5718/2648/5700/5707/55534/3280/84441/7534/102/5664/9861/8850/5698/5692/5713/5710/5719/6233/2324/5663/5706/10460/10046/5714/5688/5687/5708/59/4855/5704/23493/7311/5694/4851/5684/5720/23462/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/2033/55294/5716/54567/3516/5693/5721 77 Varicella.zoster_virus R-HSA-5687128 MAPK6/MAPK4 signaling 82/4500 89/10654 2.1884929652510664e-23 3.3234447049269428e-22 1.3281750064931985e-22 2308/5689/2118/3725/5682/27327/143471/5705/5709/5695/4609/5711/5683/5699/5702/192669/8997/4343/5062/5696/5691/7314/5879/5718/5700/122706/5707/5567/23198/3337/983/9861/5698/5692/5713/5710/8555/896/5719/6233/7514/26523/10602/5568/3315/5706/5597/5714/5566/5688/5687/5708/5063/998/5704/7311/5694/5058/27161/5684/5720/2309/10642/5690/57690/5717/9491/10197/192670/8550/7316/10213/5715/5701/5685/5686/8556/23112/5716/8202/5693/5721 82 Varicella.zoster_virus R-HSA-380259 Loss of Nlp from mitotic centrosomes 68/4500 70/10654 2.1902357654246328e-23 3.3234447049269428e-22 1.3281750064931985e-22 7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 68 Varicella.zoster_virus R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 68/4500 70/10654 2.1902357654246328e-23 3.3234447049269428e-22 1.3281750064931985e-22 7531/11190/203068/54801/79441/5116/5048/8655/9702/7846/7840/11064/5518/55835/23332/93323/1454/983/79959/10540/54930/54820/1453/9793/11258/22981/8636/7532/55125/10382/121441/7277/9814/23354/9738/1639/55722/4957/5566/7283/22919/22994/1069/5577/10383/5347/80184/22897/5108/10806/1778/115106/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/80254/9662/55142/8481/55755 68 Varicella.zoster_virus R-HSA-6807505 RNA polymerase II transcribes snRNA genes 71/4500 74/10654 2.5322140564047182e-23 3.801043895420416e-22 1.5190418221782693e-22 6884/51585/5431/5435/23379/5433/2960/55656/5439/10302/904/65123/55197/2959/79871/5438/6667/29101/79664/25896/23248/1025/7702/6829/2957/2963/5434/26173/5436/26512/6878/55756/58490/2962/51808/8812/129685/905/5452/64859/22936/6621/6880/6908/80237/6619/6882/2961/5432/22916/6618/6877/5440/57508/5430/5451/55174/6617/5441/84524/4686/2958/5437/92105/6827/80789/57117/51593/79035/1022/8178 71 Varicella.zoster_virus R-HSA-5696398 Nucleotide Excision Repair 97/4500 111/10654 3.279317230407774e-23 4.870134950690694e-22 1.946291301361837e-22 2074/10445/5982/6613/5431/5435/9978/5433/85015/10980/2965/5439/10987/2067/2967/6612/6117/7334/10714/91603/7314/6118/83444/404672/86/5438/3978/1643/5985/10920/2068/5984/6233/93973/8607/7874/5424/5886/8451/8554/10450/5434/5436/7515/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/142/125476/2071/1069/7329/51426/2873/7311/3980/60/5983/5432/51138/7528/56655/9318/6917/5440/902/27339/5430/57804/5441/7336/2072/7316/64708/5426/283899/7341/5437/10401/54617/2033/2968/56949/5887/9716/5981/57461/1022/8178/7508 97 Varicella.zoster_virus R-HSA-909733 Interferon alpha/beta signaling 67/4500 69/10654 5.081947793921649e-23 7.467788547699602e-22 2.984412554879196e-22 3443/5777/5770/3107/9021/11274/3662/3106/4599/684/3133/3429/91543/4938/5696/3445/10410/9636/2634/3444/103/3434/3433/3451/3448/3661/3439/10581/3452/4940/3437/6773/7297/5781/3430/3660/3446/3135/3665/10379/3455/4600/8638/3394/3663/6772/8651/3659/25939/3440/3454/3716/3456/3105/3441/51447/54739/2537/3449/8519/3664/6041/1958/4939/6059/3669/3134 67 Varicella.zoster_virus R-HSA-2219528 PI3K/AKT Signaling in Cancer 90/4500 101/10654 5.557144466424305e-23 8.081014244925343e-22 3.2294808850930723e-22 5295/2308/374/2250/5291/7039/3082/941/2064/145957/2534/9965/2264/9542/2885/2475/8660/2252/2253/5879/1839/5290/3667/8823/2065/3815/2069/8074/7249/2260/2249/6714/2099/2248/2932/2247/10000/7409/2246/2251/5154/3932/2931/255324/5781/253260/5170/572/4303/6199/2263/4233/64223/8503/5159/3084/208/10718/79109/5293/1956/2549/1147/8822/685/2309/842/207/1027/8817/2100/2254/152831/1950/1026/26281/10818/2261/2255/3164/5728/2066/27006/942/1385/5155/4254/5296/5156/4193 90 Varicella.zoster_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 70/4500 73/10654 5.805480436089681e-23 8.355103802867212e-22 3.339017505293035e-22 8454/5689/7291/5682/143471/5705/5709/9978/5695/5711/5683/2101/1749/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/865/11059/2099/9861/2932/6502/5698/5692/5713/5710/5719/6233/133522/5706/579/5714/6772/5688/5687/2908/5708/4488/5704/7311/860/1750/5694/57154/5684/5720/10273/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721/10891 70 Varicella.zoster_virus R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 85/4500 94/10654 8.494534203595942e-23 1.2100377294101974e-21 4.835771351134102e-22 114791/10844/440145/7531/11190/203068/54801/51807/347688/79441/10381/5116/5048/8655/9702/7846/7840/11064/5518/55835/29922/23332/93323/1454/983/79959/80097/10540/85378/54930/54820/1453/27229/9793/84617/11258/22981/8636/7532/55125/10382/121441/7277/9814/653784/23354/9738/1639/55722/4957/5566/7283/22919/10426/22994/1069/5577/10383/5347/84790/80184/22897/5108/7280/10806/1778/115106/4926/22995/55559/10142/95681/1781/80321/10121/84131/3320/10733/4751/27175/80254/9662/55142/8481/55755 85 Varicella.zoster_virus R-HSA-69615 G1/S DNA Damage Checkpoints 66/4500 68/10654 1.1785051322158486e-22 1.6618112773467925e-21 6.6412304101477915e-22 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/993/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/1111/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 66 Varicella.zoster_virus R-HSA-927802 Nonsense-Mediated Decay (NMD) 99/4500 115/10654 1.4014613223249387e-22 1.937069312837242e-21 7.74126629319664e-22 6158/9887/6138/6227/6206/6234/6191/6128/6132/6129/6224/6146/6154/26986/6202/6169/6175/6218/65109/6173/6167/6156/6143/5520/6139/23381/5518/3921/6208/5515/6203/6147/6222/2935/6134/22794/6155/4116/6231/6142/1981/6207/6233/6188/23049/5976/200916/6122/6230/6194/2107/6136/6125/6232/6160/55110/6193/6210/6229/6205/140801/6235/6181/9939/7311/6223/25873/23708/9045/6187/6168/22916/6157/6137/10921/6144/9349/4736/51121/6217/6152/51065/6141/6164/4686/6209/11224/6165/6130/6204/6228/6124/6189/23293/9775/6135/6201/6161/6133 99 Varicella.zoster_virus R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 99/4500 115/10654 1.4014613223249387e-22 1.937069312837242e-21 7.74126629319664e-22 6158/9887/6138/6227/6206/6234/6191/6128/6132/6129/6224/6146/6154/26986/6202/6169/6175/6218/65109/6173/6167/6156/6143/5520/6139/23381/5518/3921/6208/5515/6203/6147/6222/2935/6134/22794/6155/4116/6231/6142/1981/6207/6233/6188/23049/5976/200916/6122/6230/6194/2107/6136/6125/6232/6160/55110/6193/6210/6229/6205/140801/6235/6181/9939/7311/6223/25873/23708/9045/6187/6168/22916/6157/6137/10921/6144/9349/4736/51121/6217/6152/51065/6141/6164/4686/6209/11224/6165/6130/6204/6228/6124/6189/23293/9775/6135/6201/6161/6133 99 Varicella.zoster_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 77/4500 83/10654 1.5998895324051646e-22 2.189652732585892e-21 8.75068578095704e-22 8454/5689/4893/4790/5579/5682/143471/5705/5530/5709/5695/4792/5711/5683/5699/5702/3845/3265/3551/5696/5691/7314/5718/8945/4773/5966/5700/122706/5707/23198/8517/10125/5970/25780/9861/5698/5692/5713/5710/5478/5719/6233/801/805/4772/4775/5706/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/5690/5532/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5534/5716/808/5693/5721 77 Varicella.zoster_virus R-HSA-1226099 Signaling by FGFR in disease 62/4500 63/10654 1.8019691087286052e-22 2.4187969959472433e-21 9.666433477997579e-22 5295/4893/11052/2250/5335/9530/613/5431/6776/5435/5433/11064/5439/2264/2885/9846/2252/2253/3845/3265/7750/8805/26127/5290/8823/8074/2260/5438/2249/2248/399687/2247/2246/2251/6777/1523/2963/5434/5436/9208/6774/2263/6772/2962/6654/11160/2549/5432/22916/8822/5440/5430/8817/5441/2254/4686/26281/10818/2261/5437/2255/27006 62 Varicella.zoster_virus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 62/4500 63/10654 1.8019691087286052e-22 2.4187969959472433e-21 9.666433477997579e-22 5689/11065/5682/7321/8697/5705/5709/5695/5711/5683/5699/5702/51529/29945/51434/29882/5696/5691/7314/996/5718/5700/5707/51433/9861/5698/5692/5713/119504/5710/7324/5719/64682/6233/246184/5706/8881/5714/5688/5687/5708/10393/5704/51343/7311/25906/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 62 Varicella.zoster_virus R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 71/4500 75/10654 2.7887653200740875e-22 3.707729892212787e-21 1.4817499946258312e-21 23165/8683/6431/84271/199746/348995/57122/23511/65109/23279/23225/9877/9972/8021/55746/7919/6432/8563/6430/56001/80145/10762/22794/9785/11338/29107/4116/79902/9883/51213/10250/26097/51362/57187/6396/129401/79228/2733/84324/4928/5903/55706/7175/6428/10212/55110/84321/6429/4927/10569/9295/10482/8086/9939/6426/22916/10921/81929/9631/79023/23636/4686/53371/7307/9688/9984/10189/9775/84248/6427/8480 71 Varicella.zoster_virus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 85/4500 95/10654 4.738262044953594e-22 6.240201712033223e-21 2.4938221289229444e-21 6158/6138/6227/6206/6234/6191/6128/6132/6129/6224/6146/6154/26986/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/6208/6203/6147/6222/2935/6134/6155/6231/6142/1981/6207/6233/6188/5976/200916/6122/6230/6194/2107/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/23708/9045/6187/6168/22916/6157/6137/6144/9349/4736/51121/6217/6152/51065/6141/6164/4686/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 85 Varicella.zoster_virus R-HSA-162587 HIV Life Cycle 122/4500 152/10654 4.865177895159415e-22 6.347465739852845e-21 2.536688917299056e-21 6884/23165/6875/2237/7852/6874/348995/57122/5431/23511/5435/5433/2960/23279/23327/29082/23225/2965/27183/5439/6873/3836/9972/6881/2967/51616/8021/11198/904/51497/55746/7314/2959/404672/10015/91782/5438/3978/10762/4836/9397/79902/9883/89853/83860/2068/5902/5478/6233/7514/1025/6396/129401/6883/7936/6829/2957/25920/4928/2963/5434/5903/55706/7175/79643/5436/6878/920/4331/4927/8148/2966/2962/54457/8812/128866/905/2071/5901/8086/7311/93343/6880/6908/7251/1104/2547/6882/2961/5432/22916/1234/6877/5905/6917/81929/5440/902/9631/3159/5430/7520/6749/79023/5441/23636/4686/7316/6872/53371/9688/6879/9150/9525/2958/5437/6827/2968/138474/1022/8178/8480 122 Varicella.zoster_virus R-HSA-72689 Formation of a pool of free 40S subunits 89/4500 101/10654 5.861223506681744e-22 7.576174088266402e-21 3.0277275424379386e-21 6158/6138/6227/6206/6234/27335/6191/6128/6132/6129/8668/6224/6146/6154/8662/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/8665/6208/6203/6147/8666/6222/8667/6134/6155/6231/6142/8663/6207/6233/51386/6188/200916/6122/6230/6194/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/8664/9045/6187/6168/6157/6137/6144/9349/4736/51121/6217/6152/51065/6141/10480/6164/8661/6209/11224/6165/6130/6204/6228/6124/3646/6189/6135/6201/6161/6133 89 Varicella.zoster_virus R-HSA-69563 p53-Dependent G1 DNA Damage Response 64/4500 66/10654 6.3270071682619385e-22 8.029547278994243e-21 3.208912726486916e-21 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Varicella.zoster_virus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 64/4500 66/10654 6.3270071682619385e-22 8.029547278994243e-21 3.208912726486916e-21 5689/9134/5682/57060/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/8900/51230/5696/5691/7314/5718/5700/122706/5707/23198/898/890/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/25946/5690/5717/1027/9491/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721/4193 64 Varicella.zoster_virus R-HSA-5663220 RHO GTPases Activate Formins 114/4500 140/10654 1.1884705463721132e-21 1.4946890835454684e-20 5.9733465109266966e-21 55839/11130/71/6249/9735/5526/51807/9212/347688/388/147841/348995/10381/57122/1780/23122/3688/5048/57405/8655/23279/2491/7846/1060/11004/1855/9184/5518/23332/25909/10726/81930/55746/5879/5515/79682/10403/25936/1856/389/3619/64105/332/5528/6714/79902/3796/5519/81565/91687/83540/1857/7514/54820/1729/6396/64946/9793/140735/220134/84617/4928/5903/55055/80776/1783/401541/10382/79172/7277/79980/6232/5501/54821/9183/1062/699/22919/5529/51143/998/10383/5347/387/60/84790/84643/7280/1778/5516/5905/81929/54908/55143/5525/1058/991/79019/348235/80152/1063/8379/23421/55920/79023/1781/4085/5216/55166/79003/5527/701/23380/57551 114 Varicella.zoster_virus R-HSA-162599 Late Phase of HIV Life Cycle 113/4500 139/10654 2.323513380016976e-21 2.8307584745509263e-20 1.1312788354034016e-20 6884/23165/6875/6874/348995/57122/5431/23511/5435/5433/2960/23279/23327/29082/23225/2965/27183/5439/6873/9972/6881/2967/51616/8021/11198/904/51497/55746/7314/2959/404672/10015/91782/5438/10762/4836/9397/79902/9883/89853/83860/2068/5902/5478/6233/7514/1025/6396/129401/6883/7936/6829/2957/25920/4928/2963/5434/5903/55706/7175/79643/5436/6878/4331/4927/8148/2966/2962/54457/8812/128866/905/2071/5901/8086/7311/93343/6880/6908/7251/1104/6882/2961/5432/22916/6877/5905/6917/81929/5440/902/9631/5430/6749/79023/5441/23636/4686/7316/6872/53371/9688/6879/9150/9525/2958/5437/6827/2968/138474/1022/8178/8480 113 Varicella.zoster_virus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 59/4500 60/10654 2.331928542789087e-21 2.8307584745509263e-20 1.1312788354034016e-20 8454/5689/9134/5682/5705/5709/5753/5695/5711/5683/5699/5702/8900/5696/5691/7314/5718/5700/5707/898/890/9861/6502/5698/5692/5713/595/5710/5719/6233/1163/1019/5706/5714/5688/5687/5708/5704/7311/5694/1017/5684/5720/5690/5717/1027/9491/6500/10197/7316/10213/1026/5715/5701/5685/5686/5716/5693/5721 59 Varicella.zoster_virus R-HSA-5610780 Degradation of GLI1 by the proteasome 59/4500 60/10654 2.331928542789087e-21 2.8307584745509263e-20 1.1312788354034016e-20 8454/5689/5682/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/83737/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/8650/9861/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/2735/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Varicella.zoster_virus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 59/4500 60/10654 2.331928542789087e-21 2.8307584745509263e-20 1.1312788354034016e-20 8454/5689/5682/1452/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/2737/9861/2932/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 59 Varicella.zoster_virus R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 58/4500 59/10654 5.4705004718490994e-21 6.583464360949434e-20 2.631002949255919e-20 5689/5682/143471/5705/5709/5695/84515/4998/5711/5683/990/5699/5702/5001/5696/5691/7314/5718/23594/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/4999/5000/5706/5714/51053/5688/5687/5708/81620/5704/23595/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 58 Varicella.zoster_virus R-HSA-166520 Signaling by NTRKs 88/4500 101/10654 5.642599199754164e-21 6.732537164834883e-20 2.6905781159421573e-20 5295/627/9252/4893/5335/5291/1848/1785/5605/5898/1432/2534/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5879/5515/5607/161/5290/3667/5899/1849/5594/5528/9261/6714/5519/5598/4208/4909/4914/6195/1213/1211/5600/1175/6300/5781/1846/25920/4908/1173/6464/2904/7074/160/673/6774/26052/2889/6654/5900/387/2549/1020/4916/7529/5595/25759/5516/1845/4915/5604/10817/4205/57498/10818/466/53358/4803/2002/1398/1385/5906/8851/5296/581 88 Varicella.zoster_virus R-HSA-73856 RNA Polymerase II Transcription Termination 64/4500 67/10654 8.303274719249863e-21 9.823196193282042e-20 3.925723105443736e-20 8683/6431/84271/51585/199746/81608/1477/65109/9877/7919/53981/6432/8563/6430/134353/11051/80145/8106/22794/9785/11338/4116/1478/51213/10250/26097/51362/23283/6636/10914/57187/79228/84324/6635/7884/6428/10212/6637/55110/84321/6429/10898/10569/9295/51692/9939/6426/22916/1479/10921/79869/29894/4686/8189/10978/7307/9984/10189/6634/9775/84248/6427/55339/6628 64 Varicella.zoster_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 79/4500 88/10654 8.571902106736453e-21 1.0055777597482427e-19 4.0186714874571616e-20 5689/5682/5578/26986/143471/5705/5709/5695/5711/1432/5683/5699/5702/11340/8021/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/7534/9261/8741/9861/5698/5692/5713/1981/5710/5719/6233/5580/7514/5600/8570/23016/118460/1994/3842/3315/5706/8125/7538/5714/5688/5687/5708/5704/7311/51010/5694/3304/6418/167227/7529/22894/5684/5720/207/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/54512/5721 79 Varicella.zoster_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 95/4500 112/10654 9.7465054601325e-21 1.1338434685287473e-19 4.5312700823423026e-20 5295/8454/5689/5777/4893/4790/5579/5682/84876/143471/5705/5530/5709/5695/4792/5711/5683/2534/5699/5702/30011/2885/3845/3265/3551/5696/5691/7314/6786/5718/8945/4773/5966/80228/5700/122706/5707/5336/23198/8517/10125/5970/25780/9861/5698/5692/5713/5710/5478/5719/6233/7409/801/805/4772/4775/5706/6850/5714/5688/5687/4067/5708/695/6654/5704/7311/5293/5694/1147/5684/5720/6885/4690/640/5690/5532/5717/9491/6500/10197/7316/10213/10768/4793/5715/5701/23291/5685/5686/5534/5716/808/5693/5721 95 Varicella.zoster_virus R-HSA-72187 mRNA 3'-end processing 57/4500 58/10654 1.282804189532849e-20 1.4799955773453364e-19 5.914625667267595e-20 8683/6431/84271/51585/199746/81608/1477/65109/9877/7919/53981/6432/8563/6430/11051/80145/8106/22794/9785/11338/4116/1478/51213/10250/26097/51362/23283/10914/57187/79228/84324/6428/10212/55110/84321/6429/10898/10569/9295/51692/9939/6426/22916/1479/10921/79869/29894/4686/8189/10978/7307/9984/10189/9775/84248/6427/55339 57 Varicella.zoster_virus R-HSA-190236 Signaling by FGFR 78/4500 87/10654 1.8409246904702387e-20 2.1065007113905353e-19 8.418378653574e-20 5295/4893/2250/5335/54845/5431/5435/5433/9965/5439/2264/7072/2885/7073/5518/2252/2253/3845/3265/7314/5515/5290/8823/23768/5594/8074/2260/5438/3185/2249/6714/2248/4670/2247/6233/2246/2251/200734/5781/5725/2963/5434/6464/5436/673/2263/2962/23767/80004/6654/7311/53834/2549/5432/22916/5595/5516/8822/10253/5440/5430/3178/8817/10817/5441/2254/4686/7316/152831/26281/10818/2261/867/5437/2255/27006/3187/161742 78 Varicella.zoster_virus R-HSA-156842 Eukaryotic Translation Elongation 82/4500 93/10654 2.302009126730463e-20 2.5916167265449404e-19 1.0357086902946906e-19 6158/6138/6227/6206/6234/6191/6128/6132/6129/1915/6224/6146/6154/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/6208/6203/6147/6222/6134/6155/6231/6142/6207/6233/6188/200916/6122/6230/6194/1938/6136/6125/1937/6232/6160/1933/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6217/1936/6152/51065/6141/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 82 Varicella.zoster_virus R-HSA-72764 Eukaryotic Translation Termination 82/4500 93/10654 2.302009126730463e-20 2.5916167265449404e-19 1.0357086902946906e-19 6158/6138/6227/6206/6234/6191/6128/6132/6129/6224/6146/6154/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/6208/6203/51504/6147/6222/2935/6134/6155/6231/6142/6207/6233/6188/200916/6122/6230/6194/2107/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/23708/9045/6187/6168/6157/6137/6144/9349/4736/327/51121/6217/6152/51065/6141/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 82 Varicella.zoster_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 73/4500 80/10654 2.5853395747292824e-20 2.8643921002556175e-19 1.1447201124532332e-19 23165/201626/5335/348995/57122/11274/23511/4734/23279/23225/1973/3836/4599/9972/8021/7334/4938/55746/7314/402569/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/1977/51191/6233/5610/4940/6396/129401/4928/3838/5903/55706/7175/2316/4600/8638/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/1974/5595/3837/81929/9631/79023/23636/7316/53371/9688/6041/4939/6059/5300/9775/5495/8480 73 Varicella.zoster_virus R-HSA-187037 Signaling by NTRK1 (TRKA) 73/4500 80/10654 2.5853395747292824e-20 2.8643921002556175e-19 1.1447201124532332e-19 5295/9252/4893/5335/5291/1848/1785/5605/5898/1432/5603/6456/2885/8660/163/6196/1759/5518/6197/3845/3265/1399/51231/5515/5607/161/5290/3667/5899/1849/5594/5528/9261/6714/5519/5598/4208/4914/6195/1213/1211/5600/1175/6300/1846/1173/6464/160/673/6774/26052/2889/6654/5900/387/7529/5595/25759/5516/1845/4915/5604/4205/57498/10818/466/53358/4803/2002/1398/1385/5906/5296 73 Varicella.zoster_virus R-HSA-202403 TCR signaling 99/4500 119/10654 2.729188190933637e-20 2.9999580429475253e-19 1.1988974232862227e-19 5295/8454/5689/5335/4790/5682/5291/7321/143471/5705/5788/3115/5709/5695/4792/5711/5683/55824/5699/5702/26191/3127/7334/3551/5062/5696/5691/7314/5718/8945/5290/5700/122706/5707/23198/8517/5970/9861/5588/5698/5692/5713/1445/5710/916/5719/6233/3702/3932/5170/3937/3123/5706/3122/920/5714/5795/5688/5687/5708/5063/7189/7535/5704/7311/5694/5058/997/1147/55740/9402/5684/5720/6885/4690/5690/5717/9491/6500/10197/919/7316/10213/7322/5715/5701/27040/23291/915/5685/917/5686/7408/5728/7454/5716/5296/5693/5721 99 Varicella.zoster_virus R-HSA-5654738 Signaling by FGFR2 68/4500 73/10654 2.761974181245222e-20 3.01227809142057e-19 1.203820983601947e-19 5295/4893/2250/5335/54845/5431/5435/5433/5439/7072/2885/7073/5518/2252/2253/3845/3265/7314/5515/5290/8823/5594/8074/5438/3185/2249/6714/2248/4670/2247/6233/2246/2251/5781/5725/2963/5434/6464/5436/673/2263/2962/80004/6654/7311/2549/5432/22916/5595/5516/8822/10253/5440/5430/3178/8817/10817/5441/2254/4686/7316/26281/10818/867/5437/2255/27006/3187 68 Varicella.zoster_virus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 62/4500 65/10654 4.315324778788685e-20 4.657947932420478e-19 1.8614932922506815e-19 2074/5982/5431/5435/9978/5433/2965/5439/2967/6117/10714/91603/7314/6118/404672/5438/3978/5985/2068/5984/6233/7874/5424/8451/10450/5434/5436/7515/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/2071/51426/7311/3980/5983/5432/56655/6917/5440/902/27339/5430/57804/5441/7316/5426/5437/2033/2968/56949/9716/5981/57461/1022 62 Varicella.zoster_virus R-HSA-69481 G2/M Checkpoints 129/4500 168/10654 4.3376305960935685e-20 4.657947932420478e-19 1.8614932922506815e-19 5689/83990/5682/9156/1763/7531/7486/10971/5982/7533/2810/11200/143471/472/5705/5709/4174/5695/84515/4998/5711/4683/10926/5683/990/165918/84126/5699/5702/8924/55388/672/6117/7334/5001/7465/5696/83695/5691/7314/5718/6118/23594/5700/122706/5707/51588/51720/23198/63967/7534/993/116028/983/9861/9656/5698/5692/5985/5713/4175/5710/7157/5984/5719/6233/7158/5884/5810/4999/4172/80010/5000/8318/51512/7532/4173/5706/9133/580/11073/891/641/5714/6119/3364/10524/5688/5687/144715/5708/1111/5704/23595/7311/5983/5694/4176/7529/1017/5684/5720/5883/10111/8317/5690/5717/9491/545/10197/7336/29086/7316/10213/4171/5715/9088/7341/5701/5685/5686/995/5716/5932/9025/79184/7156/5693/5721 129 Varicella.zoster_virus R-HSA-156902 Peptide chain elongation 79/4500 89/10654 4.4801932442733384e-20 4.7743128007676185e-19 1.9079971229127117e-19 6158/6138/6227/6206/6234/6191/6128/6132/6129/1915/6224/6146/6154/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/6208/6203/6147/6222/6134/6155/6231/6142/6207/6233/6188/200916/6122/6230/6194/1938/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6217/6152/51065/6141/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 79 Varicella.zoster_virus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 72/4500 79/10654 5.639684853540496e-20 5.964393981471616e-19 2.383598861544229e-19 2074/5982/5431/5435/9978/5433/10980/2965/5439/10987/2067/2967/6117/10714/91603/7314/6118/404672/5438/3978/5985/10920/2068/5984/6233/7874/5424/8451/10450/5434/5436/7515/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/2071/51426/2873/7311/3980/5983/5432/51138/56655/9318/6917/5440/902/27339/5430/57804/5441/2072/7316/64708/5426/5437/2033/2968/56949/9716/5981/57461/1022/8178 72 Varicella.zoster_virus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 55/4500 56/10654 7.044895910823049e-20 7.394492249254868e-19 2.9551205640967283e-19 5689/5682/26986/143471/5705/5709/5695/5711/5683/5699/5702/3312/5696/5691/7314/5718/3303/5700/122706/5707/23198/9861/5698/5692/5713/1981/5710/5719/6233/3315/5706/5714/5688/5687/5708/5704/7311/5694/3304/5684/5720/5690/3184/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 55 Varicella.zoster_virus R-HSA-2871837 FCERI mediated NF-kB activation 74/4500 82/10654 7.126017123168585e-20 7.423820823838316e-19 2.9668413788525925e-19 8454/5689/4790/5682/7321/143471/5705/5709/5695/4792/5711/5683/5699/5702/7334/3551/5696/5691/7314/5718/8945/5700/122706/5707/23198/8517/10125/5970/9861/5588/5698/5692/5713/5710/10454/5719/6233/115727/5170/2205/5706/2206/5714/5688/5687/4067/5708/7189/5704/7311/5694/997/1147/5684/5720/6885/5690/5717/9491/6500/10197/7316/10213/7322/5715/5701/23291/5685/5686/5716/10235/5693/5721/2207 74 Varicella.zoster_virus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 58/4500 60/10654 9.648908641458832e-20 9.90432092902686e-19 3.9581436377501406e-19 8454/5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/5970/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 58 Varicella.zoster_virus R-HSA-5610783 Degradation of GLI2 by the proteasome 58/4500 60/10654 9.648908641458832e-20 9.90432092902686e-19 3.9581436377501406e-19 8454/5689/5682/1452/51684/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/9861/2932/5698/5692/5713/5710/5719/6233/5568/5706/5714/5566/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 58 Varicella.zoster_virus R-HSA-1852241 Organelle biogenesis and maintenance 201/4500 296/10654 1.5092734231420937e-19 1.5379165683988049e-18 6.146099994355049e-19 55763/5563/79738/79867/55735/79718/7531/11190/203068/54801/51807/85302/347688/79441/53632/10381/5116/3313/5048/10576/5469/10989/22832/60412/192668/8655/83658/89891/9702/132320/1432/1387/25813/7846/7840/6907/2101/11064/84902/10499/23054/5518/1386/55835/9572/85441/3054/23332/7019/93323/814/96764/10575/1454/23408/51422/10013/54806/5465/91147/54927/983/79959/5310/4208/6604/80205/8729/10540/11336/117177/57545/26005/54930/54820/23322/6742/378/56623/5600/1453/6300/801/9793/4218/133522/140735/64216/805/6102/84617/4899/5442/11258/22981/8636/54903/80776/79135/3842/3418/7532/55125/10382/23082/79809/23410/121441/7277/55112/26146/8834/9814/4209/23354/2553/146057/9738/1639/55722/4957/5566/5571/2551/7283/4580/22919/27077/22994/4867/6648/1069/211/10651/5577/10383/5347/403/84790/22948/80184/22897/5564/51106/23373/5565/5108/261734/2746/57787/7280/10806/9657/1778/55770/23265/115106/10694/22995/55559/8841/10142/6608/10640/51134/95681/200186/79989/7203/1781/80321/8766/9611/23409/79598/54205/149371/10121/347240/84131/6950/55212/3320/79600/10733/6256/4751/10498/80254/1385/200894/26123/808/54536/9662/55142/8648/8481/51259/55755/10891 201 Varicella.zoster_virus R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 54/4500 55/10654 1.6498576767330907e-19 1.656979364546327e-18 6.621920247395215e-19 8454/5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/26271/5706/5714/5688/5687/5708/5704/51343/7311/5694/5684/5720/991/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 54 Varicella.zoster_virus R-HSA-8941858 Regulation of RUNX3 expression and activity 54/4500 55/10654 1.6498576767330907e-19 1.656979364546327e-18 6.621920247395215e-19 5689/5682/5705/5709/5695/5711/5683/5699/5702/7040/5696/5691/7314/5718/5700/5707/865/6714/9861/5698/5692/5713/5710/5719/6233/1029/864/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/2033/5716/5693/5721/4193 54 Varicella.zoster_virus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 57/4500 59/10654 2.2251797246449627e-19 2.218822068288834e-18 8.86725754933707e-19 8454/5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/9861/5698/5692/5713/5710/9040/5719/6233/4791/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/23291/5685/5686/5716/5693/5721 57 Varicella.zoster_virus R-HSA-5689880 Ub-specific processing proteases 158/4500 220/10654 2.877670809736914e-19 2.8490981917678948e-18 1.1386080844797048e-18 5689/645836/5682/79594/7419/10474/7375/9817/91833/6478/3091/143471/100287513/5705/11274/55031/8239/5709/5695/4792/9986/11047/4609/392188/4194/4089/100287144/5711/4088/5683/408/64135/5699/8724/8312/100287327/5702/8900/8975/57599/377630/6881/51616/728386/1540/100287404/5696/5691/7314/5718/90865/2648/5700/122706/5707/8737/55611/100287364/57646/23198/63967/9101/8517/993/890/7417/4092/1643/9861/23586/64426/100287441/6502/5698/9146/5692/5713/5710/10454/7157/10869/9958/5719/6233/100287478/9804/23770/8607/7874/100287178/100287238/10600/23326/51651/8237/4303/409/330/5706/27005/7416/25862/9738/84132/5714/79589/55288/27430/5688/9097/5687/5708/4087/63891/84749/7189/5704/7311/367/5694/9960/23358/23032/5684/8295/5720/7186/6885/991/5690/2625/5717/9491/4086/1080/57695/10197/64750/7316/10213/8678/9100/5715/3416/5701/329/9099/5685/5686/5728/5716/9736/5693/154/10254/5721/100287205/4193 158 Varicella.zoster_virus R-HSA-199418 Negative regulation of the PI3K/AKT network 92/4500 110/10654 2.9223771849384954e-19 2.8729848944888305e-18 1.1481541201018552e-18 5295/374/3643/2250/5291/5526/7039/3082/941/2064/145957/2534/9965/2264/3630/3654/9542/2885/8660/5518/2252/2253/5879/5515/1839/5290/3667/8823/90865/2065/3815/5594/2069/8074/57761/2260/5528/2249/6714/2099/2248/5519/2247/10000/7409/2246/2251/5154/3932/8394/255324/5781/23239/2263/4233/8503/5159/3084/5529/7189/208/10718/5293/1956/2549/5595/3556/5516/8822/685/5305/5525/207/8817/4615/2100/2254/152831/1950/26281/10818/2261/2255/5728/2066/27006/942/5527/5155/4254/5296/5156 92 Varicella.zoster_virus R-HSA-1236974 ER-Phagosome pathway 74/4500 83/10654 3.8601081672653143e-19 3.744076936358894e-18 1.4962756569674365e-18 8773/5689/5682/3107/811/143471/5705/5709/5695/567/3106/5711/5683/5699/5702/3133/3551/5696/5691/7314/5718/10952/5700/122706/5707/23198/8517/6810/9861/5698/5692/5713/5710/5719/6233/3135/6890/5706/9554/29927/5714/5688/5687/5708/2923/695/5704/7311/5694/8673/3105/1147/5684/5720/5690/5717/9491/10197/7099/4615/7316/10213/5715/5701/9341/5685/5686/114609/948/5716/3134/7097/5693/5721 74 Varicella.zoster_virus R-HSA-9604323 Negative regulation of NOTCH4 signaling 53/4500 54/10654 3.8620850919461374e-19 3.744076936358894e-18 1.4962756569674365e-18 8454/5689/5682/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/5707/7534/9861/5698/5692/5713/5710/5719/6233/5706/10460/5714/5688/5687/5708/4855/5704/7311/5694/5684/5720/207/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/55294/5716/5693/5721 53 Varicella.zoster_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 86/4500 101/10654 4.067103031943977e-19 3.915638505237098e-18 1.5648381901490441e-18 8454/5689/4790/5682/7321/143471/5705/5530/5709/5695/4792/5711/5683/5699/5702/7334/3551/5696/5691/7314/5718/8945/4773/5700/122706/5707/5336/23198/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/801/4791/805/5170/4772/4775/5706/6850/5714/5688/5687/5708/7189/5704/7311/5971/5694/997/1147/5684/5720/6885/5690/3553/5532/5717/9491/6500/10197/7316/10213/10768/7322/5715/5701/23291/5685/5686/5534/5716/808/5693/5721 86 Varicella.zoster_virus R-HSA-3371556 Cellular response to heat stress 78/4500 89/10654 4.520870002485082e-19 4.322694879088476e-18 1.7275134111875227e-18 23165/573/7531/1915/817/9530/348995/472/57122/3313/23511/3305/23279/1387/23225/3309/9531/2475/3306/9972/23411/8021/6117/3312/55746/51182/818/3303/6118/5594/3308/10049/10013/3337/10762/9261/79902/9883/2932/6396/129401/3297/57521/4928/5903/55706/7175/1410/4927/64223/6119/57805/3310/7266/816/8086/3326/3304/10728/5595/815/81929/9631/545/79023/23636/10808/53371/9532/9688/7415/3320/2033/6767/22824/9529/2288/8480 78 Varicella.zoster_virus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 87/4500 103/10654 7.526948607580292e-19 7.099743416339248e-18 2.8373277112500398e-18 5295/374/3643/2250/5291/5526/7039/3082/941/2064/145957/2534/9965/2264/3630/3654/9542/2885/8660/5518/2252/2253/5879/5515/1839/5290/3667/8823/90865/2065/3815/5594/2069/8074/2260/5528/2249/6714/2099/2248/5519/2247/7409/2246/2251/5154/3932/8394/255324/5781/2263/4233/8503/5159/3084/5529/7189/10718/5293/1956/2549/5595/3556/5516/8822/685/5305/5525/207/8817/4615/2100/2254/152831/1950/26281/10818/2261/2255/2066/27006/942/5527/5155/4254/5296/5156 87 Varicella.zoster_virus R-HSA-9020702 Interleukin-1 signaling 87/4500 103/10654 7.526948607580292e-19 7.099743416339248e-18 2.8373277112500398e-18 8454/5689/4790/5682/8878/143471/5705/5709/9978/5695/4792/177/5711/5683/5699/5702/3654/7334/3551/5696/5691/7314/5718/8945/5700/122706/5707/23198/8517/5970/9861/5698/5692/5713/5710/10454/5719/6233/7850/5608/4791/3557/351/5706/79155/5714/3552/5688/5687/5708/57162/7189/5704/7311/5694/6416/3554/3556/1147/5684/5720/6885/5604/4215/5690/3553/5717/9491/6500/246330/10197/4615/7316/10213/4793/3146/5715/5701/23291/5685/5686/6288/6285/5716/57161/5693/5721 87 Varicella.zoster_virus R-HSA-69541 Stabilization of p53 55/4500 57/10654 1.1809130301263164e-18 1.1064124765478775e-17 4.4216453971525805e-18 5689/5682/11200/143471/472/5705/5709/5695/4194/5711/5683/5699/5702/51230/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/1029/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721/4193 55 Varicella.zoster_virus R-HSA-1234174 Cellular response to hypoxia 68/4500 75/10654 1.259918668330706e-18 1.1725643073264437e-17 4.686013292738766e-18 5689/5682/7321/3091/143471/5705/5709/9978/5695/5711/1387/5683/5699/7428/5702/2056/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/405/768/112399/84962/5706/5714/10370/5688/5687/5708/5704/7311/2034/55662/5694/5684/5720/7422/5690/5717/9491/10197/7316/10213/7322/5715/5701/112398/5685/5686/2033/8453/5716/54583/5693/5721 68 Varicella.zoster_virus R-HSA-180534 Vpu mediated degradation of CD4 51/4500 52/10654 2.1133044467127454e-18 1.871156608267241e-17 7.47785403696002e-18 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/8945/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/920/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Varicella.zoster_virus R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 51/4500 52/10654 2.1133044467127454e-18 1.871156608267241e-17 7.47785403696002e-18 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Varicella.zoster_virus R-HSA-69610 p53-Independent DNA Damage Response 51/4500 52/10654 2.1133044467127454e-18 1.871156608267241e-17 7.47785403696002e-18 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Varicella.zoster_virus R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 51/4500 52/10654 2.1133044467127454e-18 1.871156608267241e-17 7.47785403696002e-18 5689/5682/11200/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/993/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/1111/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Varicella.zoster_virus R-HSA-72165 mRNA Splicing - Minor Pathway 51/4500 52/10654 2.1133044467127454e-18 1.871156608267241e-17 7.47785403696002e-18 6633/6431/4904/51639/23450/5431/5435/5433/9416/8233/23020/5439/9410/10907/10262/6432/83443/10081/5438/9343/6636/2963/6635/5434/6632/24148/154007/5436/6637/55954/57819/2962/6426/5432/22916/23451/5440/55599/5430/85437/11325/5441/79622/10594/4686/5437/11066/6634/6427/10992/6628 51 Varicella.zoster_virus R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 51/4500 52/10654 2.1133044467127454e-18 1.871156608267241e-17 7.47785403696002e-18 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/2932/5698/5692/5713/595/5710/5719/6233/1019/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 51 Varicella.zoster_virus R-HSA-167161 HIV Transcription Initiation 47/4500 47/10654 2.225014304959613e-18 1.871156608267241e-17 7.47785403696002e-18 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Varicella.zoster_virus R-HSA-167162 RNA Polymerase II HIV Promoter Escape 47/4500 47/10654 2.225014304959613e-18 1.871156608267241e-17 7.47785403696002e-18 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Varicella.zoster_virus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 47/4500 47/10654 2.225014304959613e-18 1.871156608267241e-17 7.47785403696002e-18 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Varicella.zoster_virus R-HSA-6802949 Signaling by RAS mutants 47/4500 47/10654 2.225014304959613e-18 1.871156608267241e-17 7.47785403696002e-18 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Varicella.zoster_virus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 47/4500 47/10654 2.225014304959613e-18 1.871156608267241e-17 7.47785403696002e-18 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Varicella.zoster_virus R-HSA-73776 RNA Polymerase II Promoter Escape 47/4500 47/10654 2.225014304959613e-18 1.871156608267241e-17 7.47785403696002e-18 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Varicella.zoster_virus R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 47/4500 47/10654 2.225014304959613e-18 1.871156608267241e-17 7.47785403696002e-18 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Varicella.zoster_virus R-HSA-75953 RNA Polymerase II Transcription Initiation 47/4500 47/10654 2.225014304959613e-18 1.871156608267241e-17 7.47785403696002e-18 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Varicella.zoster_virus R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 47/4500 47/10654 2.225014304959613e-18 1.871156608267241e-17 7.47785403696002e-18 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/2959/404672/5438/83860/2068/6883/2957/2963/5434/5436/6878/4331/8148/2966/2962/54457/2071/6880/6908/6882/2961/5432/6877/5440/902/5430/5441/6872/6879/2958/5437/2968/138474/1022 47 Varicella.zoster_virus R-HSA-9649948 Signaling downstream of RAS mutants 47/4500 47/10654 2.225014304959613e-18 1.871156608267241e-17 7.47785403696002e-18 4893/71/817/5908/22866/5605/5037/3717/2244/3690/408/4296/5894/8826/4140/3845/3265/818/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/801/805/283455/3674/409/673/8315/816/7450/60/7529/5595/815/5604/54518/10256/5906/808/5245 47 Varicella.zoster_virus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 69/4500 77/10654 3.2841138201323926e-18 2.722939957750678e-17 1.088190452124762e-17 5689/5682/51807/63943/347688/143471/10381/5705/5709/5695/5711/7846/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/983/9861/5698/5692/5713/5710/7157/5719/6233/84617/51512/10382/7277/5706/9133/891/5714/5688/5687/5708/22919/5704/3326/7311/10383/5347/84790/5694/7280/5684/5720/5690/5717/9491/10197/7316/10213/1026/5715/5701/5685/3320/5686/5716/5693/5721 69 Varicella.zoster_virus R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 92/4500 112/10654 3.2959989307477467e-18 2.722939957750678e-17 1.088190452124762e-17 6158/6138/6227/6206/6234/6191/6128/6132/6129/6224/6146/6154/6202/6169/6175/6218/6173/6167/6156/6143/6139/6745/3921/6208/6203/10952/6147/6222/6727/6184/58477/6134/6747/6155/6729/6231/6142/6185/6207/6726/6233/6188/200916/6122/6230/6194/1650/6136/6125/6232/6160/6748/29927/6193/6210/6229/6205/28972/140801/6235/6181/7311/6223/25873/6730/9045/6187/6168/6157/6137/6144/9349/4736/51121/6217/6152/51065/6141/6164/6209/11224/6165/6130/6204/6228/6124/6189/9789/6135/6201/6161/6133 92 Varicella.zoster_virus R-HSA-1169091 Activation of NF-kappaB in B cells 62/4500 67/10654 3.2963957941251044e-18 2.722939957750678e-17 1.088190452124762e-17 8454/5689/4790/5579/5682/143471/5705/5709/5695/4792/5711/5683/5699/5702/3551/5696/5691/7314/5718/8945/5966/5700/122706/5707/23198/8517/5970/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/1147/5684/5720/6885/5690/5717/9491/6500/10197/7316/10213/4793/5715/5701/23291/5685/5686/5716/5693/5721 62 Varicella.zoster_virus R-HSA-192823 Viral mRNA Translation 77/4500 89/10654 4.1289328322517396e-18 3.3905824904843695e-17 1.3550058211104781e-17 6158/6138/6227/6206/6234/6191/6128/6132/6129/6224/6146/6154/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/6208/6203/6147/6222/6134/6155/6231/6142/6207/6233/6188/200916/6122/6230/6194/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6217/6152/51065/6141/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 77 Varicella.zoster_virus R-HSA-6782135 Dual incision in TC-NER 61/4500 66/10654 7.282912346583229e-18 5.945582243175548e-17 2.3760809748778773e-17 2074/5982/5431/5435/9978/5433/2965/5439/2067/2967/6117/10714/91603/7314/6118/404672/5438/5985/2068/5984/6233/7874/5424/8451/10450/5434/5436/54107/8450/4331/5425/5111/2966/6119/5427/1161/1642/2071/51426/7311/5983/5432/56655/6917/5440/902/27339/5430/57804/5441/2072/7316/5426/5437/2033/2968/56949/9716/5981/57461/1022 61 Varicella.zoster_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 72/4500 82/10654 8.437583186731693e-18 6.848177981789211e-17 2.7367925881075875e-17 8454/5689/5682/5526/1452/143471/5705/5709/9978/5695/5711/5683/5699/8312/5702/5518/5696/5691/7314/5515/5718/51176/8945/5700/122706/5707/23198/5528/7091/9861/5519/2932/5698/5692/5713/5710/5719/6233/10023/5706/5714/6934/5688/5687/5708/5529/5704/7311/5694/5516/5684/5720/1487/1499/5525/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/3065/5527/1488/5716/5693/5721 72 Varicella.zoster_virus R-HSA-1227986 Signaling by ERBB2 49/4500 50/10654 1.1541188234589319e-17 9.259482054877407e-17 3.700441478724948e-17 5295/4893/5335/26469/5578/2064/5753/145957/2534/4145/9542/2885/3845/3265/7314/1839/5290/2065/2069/9101/6714/10000/6233/7525/5580/1729/6464/5782/10193/3084/2886/208/6654/10718/7311/387/1956/2549/11140/8065/685/10273/207/7316/1950/51072/3320/2066/5581 49 Varicella.zoster_virus R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 49/4500 50/10654 1.1541188234589319e-17 9.259482054877407e-17 3.700441478724948e-17 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 49 Varicella.zoster_virus R-HSA-1169408 ISG15 antiviral mechanism 65/4500 72/10654 1.2752327027457153e-17 1.0172713445902963e-16 4.0654035034901005e-17 23165/5335/348995/57122/11274/23511/4734/23279/23225/1973/3836/4599/9972/8021/7334/55746/7314/402569/9636/10762/2317/3434/79902/23586/9883/1981/3661/7324/1977/51191/6233/5610/6396/129401/4928/3838/5903/55706/7175/4600/25820/1982/7706/9470/6772/4927/3840/8086/9246/3716/7311/1974/5595/3837/81929/9631/79023/23636/7316/53371/9688/5300/9775/5495/8480 65 Varicella.zoster_virus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 52/4500 54/10654 1.4356862307156636e-17 1.1387602148176513e-16 4.5509192720053935e-17 8454/5689/5682/143471/5705/5709/9978/5695/6790/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/6500/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 52 Varicella.zoster_virus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 73/4500 84/10654 1.7999185183258075e-17 1.419596752306682e-16 5.673248972421517e-17 10445/5982/6613/9978/85015/10980/2965/10987/2067/2967/6612/6117/7334/10714/7314/6118/83444/404672/86/3978/1643/5985/10920/2068/5984/6233/93973/8607/5424/5886/8451/8554/7515/54107/8450/4331/5425/5111/2966/6119/5427/1642/142/125476/2071/1069/7329/51426/2873/7311/3980/60/5983/51138/7528/56655/9318/902/57804/7336/2072/7316/64708/5426/283899/7341/10401/54617/2968/5887/5981/1022/7508 73 Varicella.zoster_virus R-HSA-177929 Signaling by EGFR 48/4500 49/10654 2.695007008417141e-17 2.1136122380619825e-16 8.446799021059049e-17 5295/374/4893/5335/7039/55824/6456/6868/30011/2885/8874/3845/3265/10252/5829/7314/1839/5290/8027/2060/2069/102/6714/9146/6455/1445/6233/29924/255324/5781/6464/5782/5796/998/6654/7311/1956/2549/10253/685/26018/58513/7316/1950/867/5774/10254/6457 48 Varicella.zoster_virus R-HSA-446652 Interleukin-1 family signaling 108/4500 140/10654 2.73979000757903e-17 2.136730084123087e-16 8.539186733413031e-17 8454/834/5689/5777/4790/5682/26469/5783/27178/8878/143471/5705/5709/9978/5695/4792/59307/3606/177/5711/4088/5683/5699/5702/3654/7334/3551/5696/5691/7314/3596/5718/8945/90865/5700/122706/5707/29110/23198/8517/3565/5970/8809/9861/5698/5692/5713/5710/10454/5719/6233/7850/5781/5608/4791/3557/351/5782/5706/79155/6774/5714/3552/5688/5687/5708/57162/5771/7189/5704/7311/5694/6416/3554/3556/1147/5778/5684/5720/6885/5604/4215/5690/3553/5717/9491/6500/25930/246330/10197/4615/7316/10213/4793/3146/5715/5701/23291/5685/5686/6288/6285/5716/5599/5784/57161/5693/5721 108 Varicella.zoster_virus R-HSA-4641258 Degradation of DVL 54/4500 57/10654 3.03756778374046e-17 2.35580257005649e-16 9.414683774166339e-17 5689/5682/143471/5705/8452/5709/9978/5695/5711/5683/5699/5702/1855/5696/5691/7314/5718/5700/122706/5707/1856/23198/9861/5698/5692/5713/5710/5719/6233/1857/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/23072/5693/5721 54 Varicella.zoster_virus R-HSA-5621481 C-type lectin receptors (CLRs) 109/4500 142/10654 3.7311584236638654e-17 2.8777332372567713e-16 1.1500517386111362e-16 8454/5689/4586/9252/4893/4790/5682/7321/143471/5705/5530/5709/5695/4792/5711/1387/5683/2534/5699/5702/5894/3845/7334/3265/3551/5062/5696/5691/7314/5718/8945/4773/4589/5700/122706/5707/5567/5336/4582/23198/841/8517/9020/5970/6714/9861/5698/5692/5713/5710/10454/9040/5719/6233/5580/801/4791/805/5170/4772/5568/4775/5706/6850/5714/5566/5688/5687/4067/5708/5063/7189/5704/30835/7311/5971/4585/5694/5058/997/1147/5684/5720/6885/5690/3553/5532/5717/9491/6500/10197/7316/10213/94025/10768/7322/5715/5701/23291/5685/5686/2033/5534/200958/5716/808/5693/5721/2207 109 Varicella.zoster_virus R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 53/4500 56/10654 6.863193539640115e-17 5.26429570403165e-16 2.1038129415900874e-16 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/9861/5698/5692/5713/5710/5719/6233/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 53 Varicella.zoster_virus R-HSA-5655253 Signaling by FGFR2 in disease 43/4500 43/10654 7.153634204246727e-17 5.457089261818815e-16 2.180860585706509e-16 5295/4893/2250/5335/5431/5435/5433/5439/2885/2252/2253/3845/3265/5290/8823/8074/5438/2249/2248/2247/2246/2251/2963/5434/5436/2263/2962/6654/2549/5432/22916/8822/5440/5430/8817/5441/2254/4686/26281/10818/5437/2255/27006 43 Varicella.zoster_virus R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/4500 52/10654 7.560408137367424e-17 5.736048782480937e-16 2.292343428377995e-16 5689/5682/143471/472/5705/5709/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/7157/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Varicella.zoster_virus R-HSA-4420097 VEGFA-VEGFR2 Pathway 82/4500 99/10654 8.549198359493882e-17 6.45117887019106e-16 2.5781366318815125e-16 5295/4893/857/5335/71/5579/5291/5578/1432/2534/9475/3690/5603/2475/6093/8440/9564/3845/3265/8877/5062/5829/5879/5290/5567/10006/57761/5921/1500/9261/6714/10810/10000/3728/7410/5580/7409/23191/3685/3791/5600/6300/801/253260/805/5170/5590/653361/6461/5747/5568/3315/10451/64223/5566/1003/10163/55845/5063/998/208/79109/2185/387/60/5058/63916/25759/558/1495/1499/4690/207/7422/10458/9047/10768/3320/4846/1398/5296/808 82 Varicella.zoster_virus R-HSA-194138 Signaling by VEGF 87/4500 107/10654 9.532262869650969e-17 7.154322024748793e-16 2.859139400631021e-16 5295/4893/857/5335/71/5579/5291/5578/7423/1432/2534/9475/3690/5603/2475/6093/8440/9564/3845/3265/8877/5062/5829/5879/5290/5567/10006/57761/5921/1500/9261/6714/2321/10810/10000/3728/7410/5580/2324/7409/23191/3685/3791/5600/6300/801/253260/805/5170/5590/653361/6461/5747/7424/5568/3315/10451/64223/5566/1003/10163/55845/5063/998/208/79109/2185/387/60/5058/63916/25759/558/1495/1499/4690/207/7422/10458/9047/10768/3320/4846/1398/5228/5296/808 87 Varicella.zoster_virus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 60/4500 66/10654 1.0393319285345366e-16 7.758862953124134e-16 3.100736966638359e-16 5689/5682/7321/3091/143471/5705/5709/9978/5695/5711/5683/5699/7428/5702/5696/5691/7314/5718/5700/122706/5707/23198/7323/9861/5698/5692/5713/5710/5719/6233/112399/84962/5706/5714/5688/5687/5708/5704/7311/2034/5694/5684/5720/5690/5717/9491/10197/7316/10213/7322/5715/5701/112398/5685/5686/8453/5716/54583/5693/5721 60 Varicella.zoster_virus R-HSA-2408557 Selenocysteine synthesis 78/4500 93/10654 1.1508184474977335e-16 8.545439110142744e-16 3.4150827389350437e-16 6158/6138/6227/6206/6234/6191/6128/6132/6129/6224/6146/6154/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/6208/6203/6147/6222/6134/60678/6155/6231/6142/6207/6233/6188/200916/6122/6230/6194/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6217/6152/51065/6141/6164/6209/11224/6165/6130/6204/6228/6124/6189/6135/6201/6161/6133 78 Varicella.zoster_virus R-HSA-8948751 Regulation of PTEN stability and activity 62/4500 69/10654 1.272648068005387e-16 9.400088375320213e-16 3.756633116362324e-16 5689/5682/1459/1460/143471/5705/5709/5695/1457/4734/5711/5683/5699/2444/5702/8975/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/10000/5692/5713/5710/5719/6233/331/23608/5706/5714/5688/5687/5708/208/5704/7311/5694/5684/5720/10273/207/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5728/5987/5716/5693/5721 62 Varicella.zoster_virus R-HSA-674695 RNA Polymerase II Pre-transcription Events 72/4500 84/10654 1.538284466495175e-16 1.1302342711722444e-15 4.516846355913811e-16 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/11198/904/51497/80349/2959/404672/5438/83860/2068/1025/23168/55677/6883/7936/6829/2957/123169/25920/2963/5434/5436/9646/6878/79577/4331/8148/2966/2962/54457/8812/905/2071/6880/6908/6882/2961/5432/22916/55840/6877/6917/5440/902/6830/5430/6749/5441/4686/6872/6879/9150/54623/2958/5437/6827/2968/138474/1022/8178 72 Varicella.zoster_virus R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 66/4500 75/10654 1.5719837758639185e-16 1.148947304243995e-15 4.591630758930157e-16 5295/374/2250/5291/7039/3082/941/2064/145957/2534/9965/2264/9542/2885/8660/2252/2253/5879/1839/5290/3667/8823/2065/3815/2069/8074/2260/2249/6714/2099/2248/2247/7409/2246/2251/5154/3932/255324/5781/2263/4233/8503/5159/3084/10718/5293/1956/2549/8822/685/8817/2100/2254/152831/1950/26281/10818/2261/2255/2066/27006/942/5155/4254/5296/5156 66 Varicella.zoster_virus R-HSA-438064 Post NMDA receptor activation events 70/4500 81/10654 1.6059403172569304e-16 1.1676524390055597e-15 4.666383597292616e-16 5563/4893/51807/817/347688/53632/10381/7846/1741/1739/6196/1740/8874/6197/3845/3265/814/5879/5923/818/5567/5594/51422/5573/2902/6714/6195/2906/801/2891/4747/805/5170/84617/3838/2904/2890/10382/5568/7277/10645/5566/84254/2905/5571/27330/3084/816/5577/5562/10383/84790/5564/5565/5924/7280/5595/815/28964/5575/114/5576/2903/4137/2066/1742/88/1385/808/8536 70 Varicella.zoster_virus R-HSA-202424 Downstream TCR signaling 81/4500 98/10654 1.6950645206068062e-16 1.2260673941798453e-15 4.899831993027583e-16 5295/8454/5689/4790/5682/5291/7321/143471/5705/3115/5709/5695/4792/5711/5683/5699/5702/3127/7334/3551/5696/5691/7314/5718/8945/5290/5700/122706/5707/23198/8517/5970/9861/5588/5698/5692/5713/5710/916/5719/6233/3932/5170/3123/5706/3122/920/5714/5688/5687/5708/7189/5704/7311/5694/997/1147/5684/5720/6885/5690/5717/9491/6500/10197/919/7316/10213/7322/5715/5701/23291/915/5685/917/5686/5728/5716/5296/5693/5721 81 Varicella.zoster_virus R-HSA-4086400 PCP/CE pathway 77/4500 92/10654 2.30951063769188e-16 1.6618952836174559e-15 6.641566131181208e-16 5689/5579/5682/5578/1212/143471/5705/5709/5695/5881/5711/5683/5699/5702/57216/1855/163/5696/5691/4920/7314/5879/5718/161/5700/122706/5707/1856/8322/23198/7471/9861/5698/5692/5713/5710/5719/6233/7474/1857/1213/1211/1175/1173/144165/409/5706/160/5714/5688/5687/4919/5708/5704/7311/387/5694/57154/5684/5720/5690/5717/9491/10197/64750/7316/10213/5216/5715/5701/5685/5686/23513/5716/5693/5721/6259 77 Varicella.zoster_virus R-HSA-72649 Translation initiation complex formation 54/4500 58/10654 2.591469789083879e-16 1.8457611354903548e-15 7.376364061302128e-16 6227/6206/1965/6234/27335/6191/8668/6224/8662/26986/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1968/6230/6194/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/6204/6228/3646/6189/6201 54 Varicella.zoster_virus R-HSA-72702 Ribosomal scanning and start codon recognition 54/4500 58/10654 2.591469789083879e-16 1.8457611354903548e-15 7.376364061302128e-16 6227/6206/1965/6234/27335/6191/8668/6224/8662/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1968/6230/6194/1983/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/6204/6228/3646/6189/6201 54 Varicella.zoster_virus R-HSA-169911 Regulation of Apoptosis 50/4500 53/10654 7.8634302945685065e-16 5.572258218892201e-15 2.22688648470281e-15 5689/5682/4976/143471/5705/5709/5695/5711/5683/5699/5702/5062/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Varicella.zoster_virus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 47/4500 49/10654 9.07675111259932e-16 6.399567956155884e-15 2.55751094613378e-15 9134/57060/2810/1869/6790/25904/1647/8900/55571/55835/57472/144455/85456/29883/1263/7027/7832/898/5934/890/10769/983/7157/5325/79733/1820/4869/4850/891/5111/246175/4848/23019/1874/1017/25946/4849/1027/9337/1026/5933/28984/2033/995/10498/581/3276 47 Varicella.zoster_virus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 61/4500 69/10654 1.3849714927917013e-15 9.715679416769924e-15 3.882755309069568e-15 23165/573/7531/9530/348995/472/57122/3313/23511/3305/23279/23225/3309/9531/3306/9972/23411/8021/6117/3312/55746/51182/3303/6118/5594/3308/10049/3337/10762/9261/79902/9883/2932/6396/129401/3297/4928/5903/55706/7175/4927/6119/57805/3310/7266/8086/3304/5595/81929/9631/545/79023/23636/10808/53371/9532/9688/6767/22824/9529/8480 61 Varicella.zoster_virus R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 54/4500 59/10654 1.799402227908403e-15 1.2559827550800654e-14 5.019385162060283e-15 6227/6206/1965/6234/27335/6191/8668/6224/8662/26986/6202/6218/1973/3921/8665/6208/6203/8666/6222/8667/6231/7458/8663/8894/1981/6207/1977/6233/51386/6188/1968/6230/6194/6232/6193/6210/6229/6205/6235/1975/6223/8664/6187/1974/6217/51065/10480/8661/6209/6204/6228/3646/6189/6201 54 Varicella.zoster_virus R-HSA-69231 Cyclin D associated events in G1 43/4500 44/10654 1.8555425529520517e-15 1.2823452494658734e-14 5.124739724151055e-15 8454/5925/1869/5753/1031/3717/5520/1032/28227/1030/5518/7314/5515/25/7027/5934/6714/5519/6502/595/896/6233/1163/1019/1029/4331/4067/1874/1870/7311/5516/894/902/1027/6500/7316/1875/1026/5933/1871/1021/1022/1028 43 Varicella.zoster_virus R-HSA-69236 G1 Phase 43/4500 44/10654 1.8555425529520517e-15 1.2823452494658734e-14 5.124739724151055e-15 8454/5925/1869/5753/1031/3717/5520/1032/28227/1030/5518/7314/5515/25/7027/5934/6714/5519/6502/595/896/6233/1163/1019/1029/4331/4067/1874/1870/7311/5516/894/902/1027/6500/7316/1875/1026/5933/1871/1021/1022/1028 43 Varicella.zoster_virus R-HSA-6783783 Interleukin-10 signaling 45/4500 47/10654 4.73663370504704e-15 3.257310666130871e-14 1.3017453272880122e-14 729230/7124/1437/3593/5743/941/3383/6349/3576/2920/1435/7133/3606/6347/3588/3569/3592/3587/6367/3976/3627/7076/7850/7297/3557/6351/6774/1440/3552/3716/1234/3586/3554/2208/3553/1230/2919/2357/6352/6348/6364/7132/942/6363/5724 45 Varicella.zoster_virus R-HSA-5678895 Defective CFTR causes cystic fibrosis 55/4500 61/10654 4.9215856739478666e-15 3.367908627858442e-14 1.3459444825554023e-14 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/5696/5691/7314/5718/5700/122706/5707/10956/79139/91445/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 55 Varicella.zoster_virus R-HSA-167172 Transcription of the HIV genome 63/4500 73/10654 6.2359202328699435e-15 4.2357903847893444e-14 1.692783067364163e-14 6884/6875/6874/5431/5435/5433/2960/2965/5439/6873/6881/2967/51616/11198/904/51497/2959/404672/5438/83860/2068/1025/6883/7936/6829/2957/25920/2963/5434/5436/6878/4331/8148/2966/2962/54457/8812/905/2071/6880/6908/6882/2961/5432/22916/6877/6917/5440/902/5430/6749/5441/4686/6872/6879/9150/2958/5437/6827/2968/138474/1022/8178 63 Varicella.zoster_virus R-HSA-180585 Vif-mediated degradation of APOBEC3G 50/4500 54/10654 6.250521627984277e-15 4.2357903847893444e-14 1.692783067364163e-14 5689/5682/143471/5705/5709/9978/5695/5711/5683/5699/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/8065/5720/5690/5717/9491/10197/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Varicella.zoster_virus R-HSA-176187 Activation of ATR in response to replication stress 37/4500 37/10654 1.2990410418411151e-14 8.760682581691771e-14 3.5011022231161514e-14 5982/4174/84515/4998/10926/990/84126/55388/6117/5001/6118/23594/63967/993/5985/4175/5984/5884/5810/4999/4172/5000/8318/4173/6119/3364/144715/1111/23595/5983/4176/1017/5883/8317/545/4171/995 37 Varicella.zoster_virus R-HSA-195258 RHO GTPase Effectors 206/4500 327/10654 1.370401274576789e-14 9.197500862063449e-14 3.6756714348466517e-14 55839/11130/71/6249/51517/5579/9735/7531/5526/51807/10971/5578/9212/347688/388/7533/2810/147841/348995/10381/57122/6280/1780/23122/3688/5048/57405/8655/10094/23279/1432/2017/2491/7846/79784/9475/1060/4628/11004/8976/1855/2885/6093/9184/8826/10499/5518/23332/25909/10726/81930/5062/55746/5879/5515/85415/25/79682/1072/10403/4638/25936/4659/10093/1856/10006/4771/389/5594/3619/64105/7534/332/5528/6714/79902/3796/5519/81565/999/10810/91687/83540/5580/1857/128239/9055/23191/7514/54820/1729/6396/5600/801/64946/9793/10109/5586/140735/5500/4221/805/3831/220134/5170/84617/4928/5590/5903/653361/55055/5747/80776/1783/401541/2316/7532/10382/10627/79172/7277/79980/6232/5501/6279/54821/10092/9183/10163/1062/699/22919/55845/5063/3895/5529/51143/998/695/10788/10097/57120/367/10383/5347/387/60/84790/84643/5058/7280/4629/7529/5595/64130/1778/5516/5905/81929/3984/27035/54908/55143/1495/1499/5525/4690/1058/991/79019/4627/348235/80152/10458/1063/8379/1027/1080/23421/55920/79023/6242/1781/10398/4085/5585/5216/10552/55166/4637/995/79003/23028/1742/5527/10096/7454/701/23380/9928/29941/103910/57551/5300/808/10095 206 Varicella.zoster_virus R-HSA-1236975 Antigen processing-Cross presentation 79/4500 99/10654 1.8462055903929373e-14 1.233159332147627e-13 4.9281740765966093e-14 8773/5689/5682/3107/811/143471/5705/5709/5695/567/3106/5711/5683/5699/5702/3133/3551/5696/5691/7314/5718/10952/5700/122706/5707/23198/8517/6810/9861/5698/5692/5713/5710/5719/6233/3685/3135/653361/6890/2209/5706/9554/29927/5714/5688/5687/5708/2923/695/9902/5704/4012/7311/5694/8673/3105/1147/5684/5720/5690/5717/9491/10197/7099/4615/7316/10213/5715/5701/9341/5685/5686/114609/948/5716/3134/7097/5693/5721 79 Varicella.zoster_virus R-HSA-3858494 Beta-catenin independent WNT signaling 107/4500 146/10654 1.922202032798719e-14 1.2778066846604819e-13 5.106601891645721e-14 5689/5579/5682/5331/5578/1212/27327/143471/5705/5530/5709/5695/5881/5711/5683/5699/2782/5702/192669/57216/1855/163/4343/3845/5696/5691/4920/7314/5879/2787/5718/51176/161/51701/5700/122706/5707/1856/8322/23198/7471/9861/5698/5692/5713/2783/2784/5710/5719/6233/7474/1857/1213/1211/1175/26523/801/805/1173/144165/4772/409/5706/160/5714/6934/5688/5687/4919/23236/5708/5704/7311/387/5694/57154/27161/815/5684/5720/6885/1499/59345/5690/5532/57690/5717/9491/10197/192670/64750/7316/10213/55970/5216/5715/5701/5685/5686/5534/23112/23513/5716/808/5693/5721/6259 107 Varicella.zoster_virus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 65/4500 77/10654 2.23280654523791e-14 1.4772502071811008e-13 5.903654123103481e-14 1912/23165/7486/6045/80012/10274/348995/6613/57122/23511/54780/1911/6672/23279/23225/165918/57332/5371/8924/672/9972/6612/8021/6117/55746/79677/51564/51588/10762/79902/9656/9883/84733/9063/6396/129401/6015/8554/4928/5903/55706/7175/1029/8535/5885/641/4927/8243/142/1069/8086/7329/648/81929/9631/79023/23636/10735/53371/6996/9688/7341/9126/8480/7508 65 Varicella.zoster_virus R-HSA-5387390 Hh mutants abrogate ligand secretion 53/4500 59/10654 2.274201305318203e-14 1.497540104822741e-13 5.984740277153166e-14 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/9861/5698/5692/5713/5710/5719/6233/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 53 Varicella.zoster_virus R-HSA-5654743 Signaling by FGFR4 40/4500 41/10654 2.3334622851062005e-14 1.5293489906142045e-13 6.111860692395782e-14 5295/4893/5335/9965/2264/2885/5518/2253/3845/3265/7314/5515/5290/8823/5594/8074/2249/6714/2247/6233/2246/2251/5781/6464/673/6654/7311/2549/5595/5516/8822/10253/8817/10817/2254/7316/152831/26281/10818/867 40 Varicella.zoster_virus R-HSA-4615885 SUMOylation of DNA replication proteins 43/4500 45/10654 2.4616502472460814e-14 1.6058241799792194e-13 6.417484658339516e-14 23165/9212/348995/6613/57122/23511/6790/23279/23225/9972/6612/8021/55746/7150/51588/3619/7153/332/10762/79902/9883/7155/6396/129401/4928/5903/55706/7175/5111/4927/8086/7329/5905/81929/55143/9631/79023/23636/53371/9688/7341/10401/8480 43 Varicella.zoster_virus R-HSA-442755 Activation of NMDA receptors and postsynaptic events 75/4500 93/10654 2.9804788680831705e-14 1.9352318603926072e-13 7.733923133826587e-14 5563/4893/51807/817/347688/53632/10381/7846/1741/1739/6196/1740/8874/6197/8825/3845/3265/814/5879/5923/818/5567/5594/51422/5573/2902/6714/6195/2906/801/2891/4747/805/5170/84617/3838/8573/2904/2890/10382/5568/7277/10645/55327/5566/84254/2905/5571/27330/3084/816/5577/5562/10383/84790/5564/5565/5924/7280/5595/64130/815/28964/5575/114/5576/2903/4137/2066/9647/1742/88/1385/808/8536 75 Varicella.zoster_virus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 36/4500 36/10654 3.089878535454522e-14 1.9877743942371027e-13 7.94390309867037e-14 4893/71/5908/22866/5605/5037/2244/3690/408/5894/8826/4140/3845/3265/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/283455/3674/409/673/7450/60/7529/5595/5604/54518/10256/5906 36 Varicella.zoster_virus R-HSA-76046 RNA Polymerase III Transcription Initiation 36/4500 36/10654 3.089878535454522e-14 1.9877743942371027e-13 7.94390309867037e-14 55718/2976/5435/9328/84265/55290/10302/9330/2972/2975/10622/7702/661/55814/11128/9533/5434/2971/10623/112495/9329/6621/6908/6619/51728/171568/10621/6618/5440/5451/6617/5441/51082/55703/27297/5437 36 Varicella.zoster_virus R-HSA-4641257 Degradation of AXIN 50/4500 55/10654 4.048927092177638e-14 2.592799183798157e-13 1.0361812452217037e-13 5689/5682/143471/5705/5709/5695/5711/5683/5699/8312/5702/5696/5691/7314/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/6233/5706/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/5716/5693/5721 50 Varicella.zoster_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 45/4500 48/10654 4.4668536417165644e-14 2.8473642391946686e-13 1.1379151310308962e-13 5295/5777/1437/5291/6776/3558/3717/2534/3563/2885/9846/1399/7314/5290/1439/7534/3718/3567/6233/7525/7409/6777/5781/3562/6464/1438/6850/5566/8503/2889/4067/3636/6654/3716/7311/5293/3561/3568/7316/3560/3055/867/1398/5296/3559 45 Varicella.zoster_virus R-HSA-4608870 Asymmetric localization of PCP proteins 56/4500 64/10654 5.6914054694154e-14 3.611455470592681e-13 1.4432750711914652e-13 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/57216/5696/5691/7314/5718/5700/122706/5707/1856/8322/23198/9861/5698/5692/5713/5710/5719/6233/7474/144165/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/23513/5716/5693/5721 56 Varicella.zoster_virus R-HSA-3928665 EPH-ephrin mediated repulsion of cells 47/4500 51/10654 6.694945129593132e-14 4.209974504915321e-13 1.6824660591201331e-13 71/2042/1947/1212/2051/2045/2050/285220/2047/2534/1948/163/284656/1759/5879/161/2046/4313/2041/102/6714/5664/1943/2043/7525/1942/7410/1213/1211/1175/5663/1173/7074/1949/1945/10451/4318/160/2049/8218/4067/2044/2048/60/1946/1944/1969 47 Varicella.zoster_virus R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 47/4500 51/10654 6.694945129593132e-14 4.209974504915321e-13 1.6824660591201331e-13 6227/6206/1965/6234/27335/6191/8668/6224/8662/6202/6218/3921/8665/6208/6203/8666/6222/8667/6231/8663/8894/6207/6233/51386/6188/1968/6230/6194/6232/6193/6210/6229/6205/6235/6223/8664/6187/6217/51065/10480/8661/6209/6204/6228/3646/6189/6201 47 Varicella.zoster_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 75/4500 94/10654 8.664510961893828e-14 5.424061570764029e-13 2.167661463206858e-13 8454/3725/9252/4790/7321/1848/4792/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/8945/5601/5606/8737/1849/29110/5594/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/2353/8772/5600/5608/4791/1846/3665/351/330/7098/79155/5602/7189/7311/6416/5595/5516/1147/1845/6885/5604/6500/7316/4205/4793/3146/7322/329/466/23291/6288/2002/6285/5609/1385/5599 75 Varicella.zoster_virus R-HSA-74751 Insulin receptor signalling cascade 49/4500 54/10654 8.778966845211126e-14 5.471177551747648e-13 2.1864908026136734e-13 5295/3643/4893/2250/5291/9965/2264/3630/2885/8660/9846/2252/2253/3845/3265/2323/54106/5290/3667/8823/5594/8074/57761/2260/2249/2248/2247/2246/2251/5781/5170/6464/2322/2263/208/6654/2549/5595/8822/8817/2254/152831/26281/10818/2261/2255/27006/5296/2887 49 Varicella.zoster_virus R-HSA-9033241 Peroxisomal protein import 55/4500 63/10654 1.1889112513756036e-13 7.376533808534856e-13 2.94794368762138e-13 26063/7321/10965/10901/1384/23600/10005/8239/3417/390916/4358/5192/7314/1891/54677/26061/8528/847/7323/2053/8309/10455/196743/11001/6233/1610/83752/373156/5264/189/3155/5193/122970/51/55825/1962/54363/5830/51179/7311/6342/5195/3295/51268/8310/7316/7322/3416/4843/5828/283927/219743/570/5194/8443 55 Varicella.zoster_virus R-HSA-168325 Viral Messenger RNA Synthesis 41/4500 43/10654 1.2736777931801585e-13 7.867496456988944e-13 3.1441510497693717e-13 23165/348995/57122/5431/23511/5435/5433/23279/23225/5439/9972/8021/55746/5438/10762/79902/9883/6396/129401/4928/2963/5434/5903/55706/7175/5436/4927/2962/8086/5432/81929/5440/9631/5430/79023/5441/23636/53371/9688/5437/8480 41 Varicella.zoster_virus R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 46/4500 50/10654 1.4708653351582635e-13 9.005824595969017e-13 3.5990703030188353e-13 5689/5682/143471/5705/5709/5695/5711/5683/5699/5702/5696/5691/5718/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/2209/5706/5714/5688/5687/5708/9902/5704/5694/5684/5720/5690/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 46 Varicella.zoster_virus R-HSA-5654736 Signaling by FGFR1 46/4500 50/10654 1.4708653351582635e-13 9.005824595969017e-13 3.5990703030188353e-13 5295/4893/2250/5335/2885/5518/2253/3845/3265/7314/5515/5290/23768/5594/8074/2260/2249/6714/2248/2247/6233/2246/2251/200734/5781/6464/673/23767/6654/7311/53834/2549/5595/5516/8822/10253/8817/10817/2254/7316/26281/10818/867/2255/27006/161742 46 Varicella.zoster_virus R-HSA-2408522 Selenoamino acid metabolism 89/4500 118/10654 1.8519770469229213e-13 1.1289781473818333e-12 4.5118264071208844e-13 6158/6138/6227/6206/6234/6191/6128/6132/6129/6224/6146/6154/6202/6169/6175/6218/6173/6167/6156/6143/6139/3921/3176/6208/7296/6203/6147/4143/191/6222/4837/2936/6134/60678/6155/6231/6142/9061/6207/6233/6188/200916/6122/6230/6194/6136/6125/6232/6160/6193/6210/6229/6205/140801/6235/6181/7311/6223/25873/9045/6187/6168/6157/6137/6144/9349/4736/51121/6217/6152/11185/51065/6141/875/6164/6209/11224/6165/6130/6204/6228/51540/7965/6124/6189/6135/6201/6161/6133 89 Varicella.zoster_virus R-HSA-2428924 IGF1R signaling cascade 48/4500 53/10654 1.8998188533864163e-13 1.153107443185842e-12 4.608256257642108e-13 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/2323/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/8471/2246/2251/5781/5170/6464/2322/2263/3481/208/6654/2549/3480/8822/8817/2254/152831/26281/10818/2261/2255/27006/3479/5296 48 Varicella.zoster_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 75/4500 95/10654 2.418498666350217e-13 1.455269025096941e-12 5.815808952657056e-13 8454/3725/9252/4790/1848/4792/59307/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/8945/5601/5606/1849/5594/4214/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/79155/8651/5602/57162/695/7189/7311/6416/5595/5516/1147/1845/6885/5604/6500/246330/7099/4615/7316/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/57161 75 Varicella.zoster_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 75/4500 95/10654 2.418498666350217e-13 1.455269025096941e-12 5.815808952657056e-13 8454/3725/9252/4790/1848/4792/59307/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/8945/5601/5606/1849/5594/4214/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/79155/8651/5602/57162/695/7189/7311/6416/5595/5516/1147/1845/6885/5604/6500/246330/7099/4615/7316/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/57161 75 Varicella.zoster_virus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 40/4500 42/10654 2.892049283195428e-13 1.7253422219405203e-12 6.895124246934669e-13 23165/348995/57122/23511/81608/23279/23225/9972/8021/55746/53981/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/7884/4927/10898/10482/51692/8086/22916/81929/9631/29894/79023/23636/4686/8189/53371/9688/10189/8480/55339 40 Varicella.zoster_virus R-HSA-3928662 EPHB-mediated forward signaling 40/4500 42/10654 2.892049283195428e-13 1.7253422219405203e-12 6.895124246934669e-13 71/1947/2051/10094/2050/2047/2534/9475/1948/8976/6093/8997/3265/5879/1072/10093/5921/6453/2902/6714/7525/10109/2904/5747/7074/1949/2049/10092/4067/998/2048/10097/387/60/5058/3984/6383/10552/10096/10095 40 Varicella.zoster_virus R-HSA-5655302 Signaling by FGFR1 in disease 37/4500 38/10654 2.9158987085463646e-13 1.732167913672649e-12 6.922402309203017e-13 5295/4893/11052/2250/5335/9530/613/6776/11064/2885/9846/2253/3845/3265/7750/8805/26127/5290/8074/2260/2249/399687/2247/2246/2251/6777/1523/9208/6774/6772/6654/11160/2549/8822/2254/26281/10818 37 Varicella.zoster_virus R-HSA-2428928 IRS-related events triggered by IGF1R 47/4500 52/10654 4.1031375903106815e-13 2.4268690143144837e-12 9.698692335897124e-13 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/2323/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/8471/2246/2251/5781/5170/2322/2263/3481/208/6654/2549/3480/8822/8817/2254/152831/26281/10818/2261/2255/27006/3479/5296 47 Varicella.zoster_virus R-HSA-1839126 FGFR2 mutant receptor activation 33/4500 33/10654 4.1548831978593236e-13 2.4268690143144837e-12 9.698692335897124e-13 2250/5431/5435/5433/5439/2252/2253/8823/8074/5438/2249/2248/2247/2246/2251/2963/5434/5436/2263/2962/5432/22916/8822/5440/5430/8817/5441/2254/4686/26281/5437/2255/27006 33 Varicella.zoster_virus R-HSA-68962 Activation of the pre-replicative complex 33/4500 33/10654 4.1548831978593236e-13 2.4268690143144837e-12 9.698692335897124e-13 5422/4174/84515/4998/10926/990/55388/6117/5001/5558/6118/23594/5557/4175/23649/4999/4172/5000/8318/54107/4173/51053/6119/5427/81620/29935/23595/4176/56655/1017/8317/5426/4171 33 Varicella.zoster_virus R-HSA-9022692 Regulation of MECP2 expression and activity 33/4500 33/10654 4.1548831978593236e-13 2.4268690143144837e-12 9.698692335897124e-13 2290/79718/817/9212/27327/28996/9612/6907/192669/4204/4343/814/818/3066/26523/801/805/3930/5566/816/25942/27161/815/8841/57690/192670/9611/2874/3064/3065/23112/1385/808 33 Varicella.zoster_virus R-HSA-5617833 Cilium Assembly 135/4500 201/10654 5.575319807823121e-13 3.2429776882171154e-12 1.2960173237483572e-12 55763/79738/79867/7531/11190/203068/54801/51807/85302/347688/79441/10381/5116/5048/10576/22832/60412/192668/8655/83658/89891/9702/132320/7846/7840/11064/84902/5518/55835/23332/93323/10575/1454/10013/54806/91147/983/79959/5310/8729/10540/11336/117177/57545/26005/54930/54820/23322/378/56623/1453/9793/4218/140735/6102/84617/11258/22981/8636/54903/80776/3842/7532/55125/10382/79809/121441/7277/55112/26146/9814/23354/146057/9738/1639/55722/4957/5566/7283/22919/27077/22994/4867/1069/5577/10383/5347/403/84790/22948/80184/22897/5108/261734/57787/7280/10806/9657/1778/55770/23265/115106/10694/22995/55559/10142/6608/10640/51134/95681/79989/7203/1781/80321/8766/79598/149371/10121/347240/84131/6950/55212/3320/79600/10733/4751/80254/200894/26123/54536/9662/55142/8481/51259/55755 135 Varicella.zoster_virus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 39/4500 41/10654 6.558568268270773e-13 3.752361189551639e-12 1.4995863598720922e-12 23165/348995/57122/23511/81608/23279/23225/9972/8021/55746/53981/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10898/10482/51692/8086/22916/81929/9631/29894/79023/23636/4686/8189/53371/9688/10189/8480/55339 39 Varicella.zoster_virus R-HSA-74158 RNA Polymerase III Transcription 39/4500 41/10654 6.558568268270773e-13 3.752361189551639e-12 1.4995863598720922e-12 55718/2976/4774/5435/9328/84265/55290/10302/9330/2972/2975/10622/7702/661/55814/11128/9533/5434/2971/10623/112495/9329/6621/6908/6619/51728/171568/10621/4784/6618/5440/5451/6617/5441/51082/55703/27297/5437/6741 39 Varicella.zoster_virus R-HSA-749476 RNA Polymerase III Abortive And Retractive Initiation 39/4500 41/10654 6.558568268270773e-13 3.752361189551639e-12 1.4995863598720922e-12 55718/2976/4774/5435/9328/84265/55290/10302/9330/2972/2975/10622/7702/661/55814/11128/9533/5434/2971/10623/112495/9329/6621/6908/6619/51728/171568/10621/4784/6618/5440/5451/6617/5441/51082/55703/27297/5437/6741 39 Varicella.zoster_virus R-HSA-8853659 RET signaling 39/4500 41/10654 6.558568268270773e-13 3.752361189551639e-12 1.4995863598720922e-12 5295/2674/1796/5335/5291/5578/55816/2668/2885/8660/9846/5623/5290/5567/4902/6714/5598/64096/220164/9260/55715/5781/6464/5568/2675/2676/5566/8503/2886/6654/5293/2549/10818/53358/5979/9048/5296/2887/9046 39 Varicella.zoster_virus R-HSA-5610787 Hedgehog 'off' state 85/4500 113/10654 8.410823009461345e-13 4.7924526209012394e-12 1.9152464855056986e-12 8454/5689/5682/1452/51684/143471/10381/5705/5709/9978/5695/5711/7846/5683/5699/5702/83737/5696/5691/7314/5718/8945/5700/122706/5707/5567/23198/112/5573/2737/5727/8650/9861/2932/5698/5692/5713/5710/5719/6233/23322/115/84617/54903/10382/79809/5568/7277/5706/5714/5566/5688/5687/5708/5577/5704/7311/10383/84790/5694/7280/5684/5720/2735/5575/6608/5690/5717/9491/6500/114/7289/10197/7316/10213/2778/5715/5701/5576/5685/5686/5716/8481/5693/5721 85 Varicella.zoster_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 73/4500 93/10654 8.608686451378424e-13 4.865476229200113e-12 1.944429498926301e-12 8454/3725/9252/4790/1848/4792/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/54106/8945/5601/5606/1849/5594/4214/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/1846/3665/351/79155/5602/57162/7189/7311/6416/51284/5595/5516/1147/1845/6885/5604/6500/246330/7099/4615/7316/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 73 Varicella.zoster_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 73/4500 93/10654 8.608686451378424e-13 4.865476229200113e-12 1.944429498926301e-12 8454/3725/9252/4790/1848/4792/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/54106/8945/5601/5606/1849/5594/4214/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/1846/3665/351/79155/5602/57162/7189/7311/6416/51284/5595/5516/1147/1845/6885/5604/6500/246330/7099/4615/7316/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 73 Varicella.zoster_virus R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 46/4500 51/10654 8.843476899388746e-13 4.978021674010762e-12 1.9894069425619846e-12 5689/5682/143471/5705/5709/5695/5711/4946/5683/5699/5702/5696/5691/5718/1728/5700/122706/5707/23198/9861/5698/5692/5713/5710/5719/5706/5714/5688/5687/5708/5704/5694/5684/5720/5690/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 46 Varicella.zoster_virus R-HSA-2871796 FCERI mediated MAPK activation 32/4500 32/10654 9.877611756414906e-13 5.472752490745048e-12 2.1871202081849463e-12 3725/4893/5335/2885/3845/3265/5062/5879/5601/5336/5594/4214/7410/7409/2353/6464/2205/3937/10451/2206/6850/4067/5602/6654/5058/6416/5595/9402/27040/5609/5599/2207 32 Varicella.zoster_virus R-HSA-5673000 RAF activation 32/4500 32/10654 9.877611756414906e-13 5.472752490745048e-12 2.1871202081849463e-12 4893/5526/817/5605/3717/4296/5894/5518/4140/3845/3265/5515/818/8844/5528/6714/5519/369/801/805/673/8315/5529/816/7529/5516/815/5604/5525/5527/808/5245 32 Varicella.zoster_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 68/4500 85/10654 9.97320877409594e-13 5.472752490745048e-12 2.1871202081849463e-12 8454/3725/9252/4790/1848/4792/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/8945/5601/5606/1849/5594/4214/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/79155/5602/57162/7189/7311/6416/5595/5516/1147/1845/6885/5604/6500/246330/4615/7316/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 68 Varicella.zoster_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 68/4500 85/10654 9.97320877409594e-13 5.472752490745048e-12 2.1871202081849463e-12 8454/3725/9252/4790/1848/4792/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/8945/5601/5606/1849/5594/4214/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/79155/5602/57162/7189/7311/6416/5595/5516/1147/1845/6885/5604/6500/246330/4615/7316/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 68 Varicella.zoster_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 68/4500 85/10654 9.97320877409594e-13 5.472752490745048e-12 2.1871202081849463e-12 8454/3725/9252/4790/1848/4792/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/8945/5601/5606/1849/5594/4214/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/79155/5602/57162/7189/7311/6416/5595/5516/1147/1845/6885/5604/6500/246330/4615/7316/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 68 Varicella.zoster_virus R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 48/4500 54/10654 1.0075196204308576e-12 5.472752490745048e-12 2.1871202081849463e-12 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/2323/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/8471/2246/2251/5781/5170/6464/2322/2263/3481/208/6654/2549/3480/8822/8817/2254/152831/26281/10818/2261/2255/27006/3479/5296 48 Varicella.zoster_virus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 48/4500 54/10654 1.0075196204308576e-12 5.472752490745048e-12 2.1871202081849463e-12 2074/5431/5435/9978/5433/10980/2965/5439/10987/2967/91603/7314/404672/5438/10920/2068/6233/7874/8451/10450/5434/5436/8450/4331/2966/1161/1642/2071/2873/7311/5432/51138/9318/6917/5440/902/27339/5430/5441/7316/64708/5437/2033/2968/56949/9716/57461/1022 48 Varicella.zoster_virus R-HSA-8848021 Signaling by PTK6 48/4500 54/10654 1.0075196204308576e-12 5.472752490745048e-12 2.1871202081849463e-12 4893/1796/5770/2909/9021/27043/3091/2064/5753/145957/9542/9564/3845/3265/5829/7314/5879/120892/1839/2065/2069/898/5921/6421/595/6233/1019/10657/6774/2908/3084/10718/7311/2034/387/1956/63916/1017/685/207/55620/1027/10457/7316/1950/867/2066/1398 48 Varicella.zoster_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 48/4500 54/10654 1.0075196204308576e-12 5.472752490745048e-12 2.1871202081849463e-12 4893/1796/5770/2909/9021/27043/3091/2064/5753/145957/9542/9564/3845/3265/5829/7314/5879/120892/1839/2065/2069/898/5921/6421/595/6233/1019/10657/6774/2908/3084/10718/7311/2034/387/1956/63916/1017/685/207/55620/1027/10457/7316/1950/867/2066/1398 48 Varicella.zoster_virus R-HSA-447115 Interleukin-12 family signaling 50/4500 57/10654 1.0675957221177075e-12 5.776603209598138e-12 2.308550521103162e-12 3593/5908/3313/6175/3936/5898/3717/3181/4001/3594/4282/5062/3572/10148/1072/3592/6627/9049/27250/9987/3185/149233/3458/5478/302/552900/51561/7297/6775/3595/821/4478/6774/6772/998/6648/3716/2939/6888/246778/3586/829/6647/6950/9466/4507/6845/375/5721/5034 50 Varicella.zoster_virus R-HSA-451927 Interleukin-2 family signaling 41/4500 44/10654 1.102366316543942e-12 5.941711883765803e-12 2.3745342319377742e-12 5295/5777/1437/5291/6776/3558/3717/3563/2885/9846/3600/5290/1439/50615/3718/3567/3932/6777/59067/3562/6464/6775/1438/3581/6774/6850/6772/8503/3636/6654/3716/5293/2185/6655/3561/3578/3568/3560/5296/3559/3601 41 Varicella.zoster_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 94/4500 129/10654 1.3251755396272822e-12 7.1151732819987915e-12 2.843494072884452e-12 8454/3725/9252/4790/7321/1848/1785/4792/59307/177/1432/3654/6196/1759/5518/1386/6197/7334/3551/51231/7314/5515/8945/5601/5606/8737/5336/1849/29110/5594/4214/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/2353/8772/5600/5781/5608/4791/1846/3665/351/3684/330/79155/8651/26052/5602/57162/695/7189/7311/6416/5595/5516/1147/1845/6885/5604/6500/246330/7099/4615/7316/4205/4793/3146/7322/329/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/3929/57161/3689 94 Varicella.zoster_virus R-HSA-5654741 Signaling by FGFR3 38/4500 40/10654 1.4854082002435471e-12 7.914617738702259e-12 3.1629825075495383e-12 5295/4893/2250/5335/2885/5518/2253/3845/3265/7314/5515/5290/8823/5594/8074/2249/6714/2247/6233/2246/5781/6464/673/6654/7311/2549/5595/5516/8822/10253/8817/10817/2254/7316/26281/10818/2261/867 38 Varicella.zoster_virus R-HSA-5674135 MAP2K and MAPK activation 38/4500 40/10654 1.4854082002435471e-12 7.914617738702259e-12 3.1629825075495383e-12 4893/71/84292/5908/22866/5605/5037/2244/54756/3690/408/5894/8826/4140/3845/3265/8844/7094/5594/7414/6714/2335/1445/2266/2243/369/283455/3674/409/673/7450/60/7529/5595/5604/54518/10256/5906 38 Varicella.zoster_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 72/4500 92/10654 1.6170622402552706e-12 8.583341777172463e-12 3.43023008739361e-12 8454/3725/9252/4790/1848/4792/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/54106/8945/5601/5606/1849/5594/4214/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/1846/351/79155/5602/57162/7189/7311/6416/51284/5595/5516/1147/1845/6885/5604/6500/246330/7099/4615/7316/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 72 Varicella.zoster_virus R-HSA-5689603 UCH proteinases 78/4500 102/10654 1.6809713546007564e-12 8.888772769025213e-12 3.5522919375534334e-12 5689/221937/5682/4738/10445/143471/5705/5709/5695/11047/5711/7347/5683/55777/5699/5702/7040/7345/3054/5696/5691/7314/5718/3607/5700/122706/5707/83444/171023/23198/86/4092/9861/5698/5692/5713/5710/8473/9958/5719/6233/93973/8607/114785/5706/580/5714/5688/5687/5708/125476/5704/7048/7311/60/5694/7528/5684/5720/51377/5690/5717/9491/10197/7316/10213/8314/55252/5715/283899/5701/5685/54617/5686/221656/5716/5693/5721 78 Varicella.zoster_virus R-HSA-5358346 Hedgehog ligand biogenesis 55/4500 65/10654 1.9041962046850376e-12 9.993450758422228e-12 3.993763310182311e-12 5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/6868/6469/5696/5691/7314/5718/5700/122706/5707/10956/23198/9861/5698/5692/5713/5710/5719/6233/5706/84447/5714/5688/5687/5708/5704/7311/5694/5684/5720/5690/5717/9491/10197/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721/5034 55 Varicella.zoster_virus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 55/4500 65/10654 1.9041962046850376e-12 9.993450758422228e-12 3.993763310182311e-12 3725/4436/472/5431/5435/5433/2965/5439/672/2967/1386/11198/904/51497/2176/404672/5438/1643/9656/2068/7157/1025/2353/7936/6829/25920/2963/5434/5436/4292/4331/2966/2962/8812/905/1111/2071/55215/5432/6917/5440/8621/902/5430/6749/545/5441/5395/9150/5437/51755/6827/2968/1022/8178 55 Varicella.zoster_virus R-HSA-166166 MyD88-independent TLR4 cascade 76/4500 99/10654 2.294176699823565e-12 1.1950263705051107e-11 4.775780247079691e-12 8454/3725/9252/4790/7321/1848/4792/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/8945/5601/5606/8737/1849/29110/5594/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/2353/8772/5600/5781/5608/4791/1846/3665/351/330/79155/5602/7189/7311/6416/5595/5516/1147/1845/6885/5604/6500/7099/7316/4205/4793/3146/7322/329/466/23291/6288/2002/6285/5609/1385/5599 76 Varicella.zoster_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 76/4500 99/10654 2.294176699823565e-12 1.1950263705051107e-11 4.775780247079691e-12 8454/3725/9252/4790/7321/1848/4792/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/8945/5601/5606/8737/1849/29110/5594/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/2353/8772/5600/5781/5608/4791/1846/3665/351/330/79155/5602/7189/7311/6416/5595/5516/1147/1845/6885/5604/6500/7099/7316/4205/4793/3146/7322/329/466/23291/6288/2002/6285/5609/1385/5599 76 Varicella.zoster_virus R-HSA-182971 EGFR downregulation 31/4500 31/10654 2.3479496461936647e-12 1.2139769281801318e-11 4.851513888821218e-12 374/7039/6456/30011/2885/8874/10252/7314/1839/8027/2060/2069/9146/6455/6233/29924/255324/5782/5796/998/7311/1956/10253/685/58513/7316/1950/867/5774/10254/6457 31 Varicella.zoster_virus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 31/4500 31/10654 2.3479496461936647e-12 1.2139769281801318e-11 4.851513888821218e-12 3725/9252/1848/1432/6196/5518/1386/6197/51231/5515/5601/1849/5594/5528/9261/5519/5598/4208/6195/2353/5600/1846/5602/5595/5516/1845/4205/466/2002/1385/5599 31 Varicella.zoster_virus R-HSA-450294 MAP kinase activation 54/4500 64/10654 3.84793934544624e-12 1.9821857292409414e-11 7.921568666096359e-12 8454/3725/9252/4790/1848/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/8945/5601/5606/1849/5594/8517/5528/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/1846/79155/5602/7189/7311/6416/5595/5516/1147/1845/6885/5604/6500/7316/4205/466/23291/2002/5609/1385/5599 54 Varicella.zoster_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 75/4500 98/10654 4.216261080498548e-12 2.156007497573616e-11 8.616226615246694e-12 8454/3725/9252/4790/1848/4792/59307/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/8945/5601/5606/1849/5594/4214/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/79155/8651/5602/57162/695/7189/7311/6416/5595/5516/1147/1845/6885/5604/6500/246330/7099/4615/7316/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/57161 75 Varicella.zoster_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 75/4500 98/10654 4.216261080498548e-12 2.156007497573616e-11 8.616226615246694e-12 8454/3725/9252/4790/1848/4792/59307/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/8945/5601/5606/1849/5594/4214/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/4791/1846/351/79155/8651/5602/57162/695/7189/7311/6416/5595/5516/1147/1845/6885/5604/6500/246330/7099/4615/7316/4205/4793/3146/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/57161 75 Varicella.zoster_virus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 59/4500 72/10654 4.721793665715453e-12 2.405702174211231e-11 9.614101585974609e-12 8773/55763/5563/71/7531/51807/10971/347688/7533/2810/53632/10381/60412/5898/7846/51552/5879/51422/4644/7534/6810/5872/4641/11336/6844/9882/79058/801/4218/805/84617/7532/57186/10382/7277/5571/208/5867/4012/10383/60/84790/5564/5565/7280/7529/55770/23265/6517/10890/10640/4627/207/8766/149371/9847/808/54536/6814 59 Varicella.zoster_virus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 30/4500 30/10654 5.58045123963348e-12 2.8225760617856297e-11 1.1280088318099713e-11 56852/5982/9978/57599/6117/10714/7314/51514/6118/5985/5984/6233/5424/8451/54107/8450/5425/5111/6119/5427/1642/7311/5983/56655/57804/7320/7316/5426/7398/5981 30 Varicella.zoster_virus R-HSA-5654696 Downstream signaling of activated FGFR2 30/4500 30/10654 5.58045123963348e-12 2.8225760617856297e-11 1.1280088318099713e-11 5295/4893/2250/5335/2885/2252/2253/3845/3265/5290/8823/8074/2249/2248/2247/2246/2251/5781/6464/2263/6654/2549/8822/8817/10817/2254/26281/10818/2255/27006 30 Varicella.zoster_virus R-HSA-73894 DNA Repair 202/4500 334/10654 7.35584651602855e-12 3.7071342008577094e-11 1.4815119336861608e-11 2237/4436/221120/83990/151987/9156/2074/1763/7486/27343/4913/56852/10445/5982/11200/472/6613/27434/5431/5435/9978/5433/85015/10980/64421/4683/2965/25898/165918/84126/5439/10987/8900/8924/57599/2067/672/2967/6612/121642/6117/7334/10973/10714/55666/348654/91603/83695/55183/7314/51514/7014/6118/2176/25/5888/322/328/83444/51588/51720/63967/404672/5531/9636/86/5438/3978/11201/116028/890/1643/9656/51455/5985/10920/29089/2068/7157/5984/4595/4255/6233/7158/6047/93973/55247/8607/7874/5884/5810/5424/5886/8451/8554/10450/8467/80010/3838/5434/5436/2956/7515/54107/7013/4292/7706/580/11073/5591/8450/4331/5425/641/5111/2966/6119/3364/22976/10524/5427/144715/1161/1642/142/125476/1111/2071/55215/1069/7329/9246/79728/51426/2873/7311/4968/3980/60/5536/5983/2175/2547/79840/5432/51138/7528/56655/9318/1017/25913/6917/5440/2178/902/5883/27339/5430/10111/57804/7320/7520/675/51548/545/5441/7336/2072/29086/7316/6996/64708/8314/5426/9100/10635/7415/5395/283899/7341/5437/10401/54617/2033/7398/2968/5932/9025/2189/79184/56949/7156/5887/9716/5599/5981/57461/1022/2139/8178/5980/7508 202 Varicella.zoster_virus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 36/4500 38/10654 7.587787702668629e-12 3.810270371555901e-11 1.52272907323528e-11 23165/348995/57122/23511/23279/23225/7428/5371/9972/8021/55746/51588/10762/79902/9883/9063/6396/129401/8554/4928/5903/55706/7175/4927/8086/7329/81929/9631/79023/23636/53371/9688/7341/5987/8480/4193 36 Varicella.zoster_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 74/4500 97/10654 7.724552079374167e-12 3.865044696346357e-11 1.544618978331752e-11 8454/3725/9252/4790/1848/4792/177/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/54106/8945/5601/5606/1849/5594/4214/8517/5528/5970/9261/5519/5598/4208/6195/10454/6233/51311/2353/5600/5608/4791/1846/3665/351/8411/79155/5602/57162/7189/7311/6416/51284/5595/5516/1147/1845/6885/5604/6500/246330/7099/4615/7316/4205/4793/3146/466/23291/6288/2002/6285/5609/1385/5599/57161 74 Varicella.zoster_virus R-HSA-5654727 Negative regulation of FGFR2 signaling 33/4500 34/10654 8.359956727541022e-12 4.1680355684454524e-11 1.665705663758174e-11 2250/2885/5518/2252/2253/7314/5515/8823/5594/8074/2249/6714/2248/2247/6233/2246/2251/5781/673/2263/7311/5595/5516/8822/10253/8817/2254/7316/26281/10818/867/2255/27006 33 Varicella.zoster_virus R-HSA-112399 IRS-mediated signalling 43/4500 48/10654 8.738000959169174e-12 4.341013999644188e-11 1.7348344290540037e-11 5295/4893/2250/5291/9965/2264/2885/8660/9846/2252/2253/3845/3265/2323/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/2246/2251/5781/5170/2322/2263/208/6654/2549/8822/8817/2254/152831/26281/10818/2261/2255/27006/5296 43 Varicella.zoster_virus R-HSA-6806834 Signaling by MET 63/4500 79/10654 8.958687799669027e-12 4.4348681448006954e-11 1.7723421178889826e-11 5295/3675/4893/5770/3249/5908/3082/3688/3910/6456/30011/2885/3845/3265/1399/7314/5879/3918/5290/8027/2060/284217/9101/6714/9146/6455/2335/64759/84951/6233/57610/5781/6464/85440/5747/382/1277/3912/6774/4233/5795/2889/5771/3913/6654/5867/7311/2549/26018/10048/7316/3915/1281/3673/867/3914/200958/1398/5906/23163/1278/10254/6457 63 Varicella.zoster_virus R-HSA-168898 Toll-like Receptor Cascades 107/4500 155/10654 1.0677000969157158e-11 5.266817439202613e-11 2.1048207229508256e-11 8454/3725/10695/9252/4790/7321/1848/1785/6280/4792/59307/177/1432/2244/3654/6196/1759/5518/1386/6197/7334/3551/51231/7314/5515/54106/8945/5601/5606/8737/5336/1849/29110/5594/4214/841/8517/5528/7323/5970/9261/5519/5598/4208/6195/10454/3661/6233/51311/2266/2353/2243/8772/5600/5781/5608/4791/1846/3665/351/7184/3684/8411/330/7098/338/79155/6279/8651/26052/5602/57162/695/7189/7311/6416/51284/5595/5516/1147/1845/6885/5604/6500/246330/7099/4615/7316/4205/4793/3146/7322/329/466/23291/114609/6288/2002/6285/5609/948/1385/5599/7097/3929/57161/3689 107 Varicella.zoster_virus R-HSA-186763 Downstream signal transduction 29/4500 29/10654 1.3261528611296214e-11 6.518695049777998e-11 2.6051186671560393e-11 5295/4893/5335/5291/6776/2885/8440/9564/3845/3265/1399/5290/5921/6778/6714/5154/6777/5781/6774/6772/2889/5159/2886/6654/4690/1398/5155/5296/5156 29 Varicella.zoster_virus R-HSA-9614085 FOXO-mediated transcription 54/4500 65/10654 1.338995112736509e-11 6.558726938176024e-11 2.621116933519298e-11 2308/857/2290/65018/57060/356/10971/7295/2810/4089/1647/1387/4088/10628/4801/3630/23411/7534/847/5934/5443/8850/10000/3066/604/5105/7532/4303/23410/4287/4800/901/9314/10370/2908/6794/6648/4087/208/25942/7529/27113/2309/10018/4802/207/1027/6720/1649/114907/1026/2033/3065/10891 54 Varicella.zoster_virus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 67/4500 86/10654 1.4106595764566705e-11 6.885597093473818e-11 2.7517466894443702e-11 5295/5335/71/51517/5291/2268/10094/2534/8976/2885/5879/25/1072/5290/10093/10006/5336/4771/5594/4644/4641/6714/10810/7525/7410/5580/7409/23191/10109/2214/5747/2209/10451/6850/10092/4650/10163/4067/55845/998/695/3326/10097/60/5058/63916/5595/3984/23646/4690/4627/10458/919/3055/10552/10768/4620/917/3320/1398/10096/7454/5296/5581/5338/10095/2212 67 Varicella.zoster_virus R-HSA-8878171 Transcriptional regulation by RUNX1 152/4500 239/10654 1.45700795217764e-11 7.087049133240368e-11 2.832254592533099e-11 1912/9070/5689/1437/5579/5682/1459/6045/9021/5929/27327/80012/1460/143471/5705/5709/5695/28996/1457/1911/6603/10413/5711/1387/3558/5683/10138/57332/5699/8312/5702/192669/83737/5371/57492/6688/4343/5696/5691/7314/5718/84661/25/4773/8861/5700/122706/5707/23198/86/100506658/865/7082/23309/6714/2099/9861/8850/84733/5588/6604/8289/5698/5692/5713/6602/595/5710/3458/896/5719/23067/6233/26523/5781/1493/23429/6015/55904/6595/3562/6597/8535/3674/6938/3958/5706/6599/4331/57678/2623/5714/5688/5687/5708/4602/5704/7311/7161/860/58508/25942/648/5694/6601/23466/4297/4004/27161/894/5684/5720/902/2624/11091/640/8085/5690/2625/57690/5717/9491/4005/6598/10197/192670/7316/10213/5079/10398/122809/5715/5701/5685/5686/2033/1021/6605/50943/3065/861/23112/9757/5716/9739/3276/3977/3559/7057/1022/5693/5721 152 Varicella.zoster_virus R-HSA-72766 Translation 179/4500 291/10654 1.5619275089037516e-11 7.571009730658463e-11 3.0256636685635545e-11 6158/6138/5464/6227/6206/1965/6234/27335/6191/6128/6132/84545/6129/1915/80222/8668/6224/6146/6154/8662/26986/6202/65003/55052/6169/6175/6218/6173/64968/6167/118487/28977/6156/6143/1973/124995/28973/51116/6139/6745/64975/3921/8665/10667/65005/84340/6208/92935/6203/51504/51253/10952/6147/8666/6222/64432/4528/8667/6727/6184/79731/58477/2935/6134/6747/55699/6155/55157/10240/6729/6231/6142/7458/8663/23107/8894/1981/85476/6185/6207/64978/1977/6726/6233/28957/51386/6188/26589/64965/7284/200916/6122/1968/6230/6194/2107/1938/1650/1983/6136/6125/1937/23395/6232/6160/6748/29927/1933/6193/6210/6229/6205/54148/28972/140801/23438/79587/6235/51263/6181/740/8893/1975/7311/6223/25873/8664/6730/23708/9045/6187/6168/6157/6137/1974/55037/51264/6144/10352/9349/4736/8891/327/51121/56945/6217/1936/6152/79590/51065/6141/10480/1967/6164/63931/8661/64963/9669/6209/11224/6165/6130/8890/6204/64969/6228/7965/6124/2193/3646/6189/9789/6135/6201/6161/51649/54998/8892/6133 179 Varicella.zoster_virus R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 40/4500 44/10654 1.5893706232966275e-11 7.677375052325578e-11 3.068171299753097e-11 834/79370/55367/472/1387/51499/7159/637/27166/23368/332/64065/8797/7157/604/63970/839/317/5875/55240/5366/84883/147923/843/94241/8626/7161/10397/8795/665/27113/9540/8793/58484/3486/355/8794/124446/5876/581 40 Varicella.zoster_virus R-HSA-5685938 HDR through Single Strand Annealing (SSA) 35/4500 37/10654 1.711158994353315e-11 8.208858955729304e-11 3.280572497765444e-11 83990/9156/1763/7486/5982/472/4683/84126/2067/672/6117/83695/6118/25/5888/116028/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/5983/5883/10111/545/2072/5932/7156 35 Varicella.zoster_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 35/4500 37/10654 1.711158994353315e-11 8.208858955729304e-11 3.280572497765444e-11 11200/472/639/4194/8900/2475/5518/51230/7314/5515/117584/890/983/5519/10000/900/7157/6233/7874/253260/5170/1029/80196/64223/1616/208/79109/7311/5516/1017/207/7316/9099/5527/4193 35 Varicella.zoster_virus R-HSA-4570464 SUMOylation of RNA binding proteins 42/4500 47/10654 1.8662500048105334e-11 8.922208927107893e-11 3.5656542990251726e-11 1912/23165/6045/80012/348995/6613/57122/23511/3190/1911/23279/23225/57332/9972/8021/55746/51602/10762/79902/9883/84733/6396/129401/6015/4928/5903/55706/7175/8535/4927/8086/7329/648/81929/9631/79023/23636/3183/53371/9688/7341/8480 42 Varicella.zoster_virus R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 48/4500 56/10654 1.9250286421910326e-11 9.133385633211755e-11 3.650048548938494e-11 79718/5469/1387/6907/2101/10499/23054/1386/9572/85441/3054/7019/814/96764/23408/5465/4208/6604/80205/6742/801/133522/64216/805/4899/5442/3418/23082/23410/4209/2553/2551/6648/211/51106/23373/2746/8841/200186/9611/23409/54205/6256/10498/1385/808/8648/10891 48 Varicella.zoster_virus R-HSA-113418 Formation of the Early Elongation Complex 32/4500 33/10654 1.930049256301911e-11 9.133385633211755e-11 3.650048548938494e-11 5431/5435/5433/2965/5439/2967/51497/404672/5438/2068/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/4686/9150/5437/6827/2968/1022 32 Varicella.zoster_virus R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 32/4500 33/10654 1.930049256301911e-11 9.133385633211755e-11 3.650048548938494e-11 5431/5435/5433/2965/5439/2967/51497/404672/5438/2068/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/4686/9150/5437/6827/2968/1022 32 Varicella.zoster_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 46/4500 53/10654 2.0174123346147216e-11 9.450696708463595e-11 3.776858132623817e-11 7531/55075/10971/7533/2810/1869/8655/836/90427/840/7159/637/578/23368/7027/5594/841/7534/4836/598/10000/708/7157/331/317/140735/1029/572/7532/6774/5366/8626/208/7161/7529/5595/5533/27113/596/10018/842/207/54205/5534/581/5599 46 Varicella.zoster_virus R-HSA-191859 snRNP Assembly 46/4500 53/10654 2.0174123346147216e-11 9.450696708463595e-11 3.776858132623817e-11 23165/6633/6606/25929/348995/57122/23511/23279/23225/79084/9972/8021/55746/96764/10762/79902/9883/6636/10419/6396/129401/50628/4928/6635/5903/6632/55706/7175/6637/4927/51808/8086/79833/22916/81929/11218/9631/79023/23636/4686/53371/9688/1207/6634/8480/6628 46 Varicella.zoster_virus R-HSA-194441 Metabolism of non-coding RNA 46/4500 53/10654 2.0174123346147216e-11 9.450696708463595e-11 3.776858132623817e-11 23165/6633/6606/25929/348995/57122/23511/23279/23225/79084/9972/8021/55746/96764/10762/79902/9883/6636/10419/6396/129401/50628/4928/6635/5903/6632/55706/7175/6637/4927/51808/8086/79833/22916/81929/11218/9631/79023/23636/4686/53371/9688/1207/6634/8480/6628 46 Varicella.zoster_virus R-HSA-8868773 rRNA processing in the nucleus and cytosol 128/4500 195/10654 2.5816971065148125e-11 1.2053676122724677e-10 4.817107785435138e-11 6158/6138/6227/6206/6234/6191/6128/6132/6129/55226/10528/84135/27043/6224/6146/6154/88745/6202/6169/55272/6175/6218/5394/6173/6167/23481/51077/6156/117246/6143/6139/26168/11340/3921/10607/11103/6208/10813/9136/6203/51504/6147/27292/6222/1454/56902/51602/6134/6155/6231/6142/6207/10969/6233/6188/54881/1453/4691/23016/118460/200916/6122/6230/2091/55651/55127/6194/8780/6136/6125/4839/6232/134430/6160/92856/65083/6193/10200/6210/6229/6205/9790/140801/6235/6181/7311/6223/25873/55505/51010/26354/51202/9045/6187/6168/6157/6137/22894/6144/9349/55813/4736/22803/51121/25879/6217/81887/6152/51065/6141/55781/6164/6209/11224/6165/6130/6204/6228/10199/6124/83732/6189/6135/6201/6161/54512/6133/9188 128 Varicella.zoster_virus R-HSA-5632684 Hedgehog 'on' state 66/4500 85/10654 2.629258878609635e-11 1.2234817981796834e-10 4.8894989672389706e-11 5689/5682/22873/1452/51684/143471/5705/8452/5709/9978/5695/5711/5683/408/5699/5702/83737/6469/5696/5691/7314/5718/5700/122706/5707/23198/2737/5727/8650/9861/5698/5692/5713/5710/5719/6233/23288/409/79577/5706/5714/5688/5687/5708/5704/7311/5694/57154/5684/5720/2735/6608/5690/5717/9491/10197/64750/7316/10213/5715/5701/5685/5686/5716/5693/5721 66 Varicella.zoster_virus R-HSA-5675221 Negative regulation of MAPK pathway 37/4500 40/10654 2.647492306638859e-11 1.2278735083281884e-10 4.907049912637159e-11 4893/1844/1850/1848/5526/1852/5605/5037/5894/1847/5518/4140/3845/3265/7314/5515/8844/1849/5594/5528/5519/6233/1843/369/1846/673/8315/5529/7311/5536/7529/5595/5516/5604/5525/7316/5527 37 Varicella.zoster_virus R-HSA-8943724 Regulation of PTEN gene transcription 51/4500 61/10654 3.1198030947345625e-11 1.4421341457779634e-10 5.76331697528518e-11 1912/3725/6591/1822/9112/6045/80012/1911/5928/23512/57332/1107/2475/1386/64121/23186/2146/51564/5594/84232/7101/84733/57459/3066/7157/8726/57521/6015/9219/8535/5931/1108/2122/64223/10014/54815/55004/57504/648/23466/53615/5595/8841/5468/5978/57167/1958/6615/3065/23028/10542 51 Varicella.zoster_virus R-HSA-76061 RNA Polymerase III Transcription Initiation From Type 1 Promoter 28/4500 28/10654 3.1510957742315384e-11 1.4470163489563247e-10 5.782828117530179e-11 55718/2976/5435/9328/84265/9330/2972/2975/10622/661/55814/11128/9533/5434/2971/10623/112495/9329/6908/51728/171568/10621/5440/5441/51082/55703/27297/5437 28 Varicella.zoster_virus R-HSA-76071 RNA Polymerase III Transcription Initiation From Type 3 Promoter 28/4500 28/10654 3.1510957742315384e-11 1.4470163489563247e-10 5.782828117530179e-11 55718/5435/84265/55290/10302/10622/7702/661/55814/11128/9533/5434/10623/6621/6908/6619/51728/171568/10621/6618/5440/5451/6617/5441/51082/55703/27297/5437 28 Varicella.zoster_virus R-HSA-1433557 Signaling by SCF-KIT 39/4500 43/10654 3.4431486283504674e-11 1.5759460607138533e-10 6.298080321055213e-11 5295/5777/4893/5578/6776/3717/2534/2885/9846/3845/3265/5879/5290/3815/9306/6714/7525/7409/3932/6777/5781/10019/2241/4318/6774/6772/8651/8503/4067/1111/2886/6654/9402/867/4254/5296/10076/2887/2242 39 Varicella.zoster_virus R-HSA-177243 Interactions of Rev with host cellular proteins 34/4500 36/10654 3.852864670691088e-11 1.7519866711025274e-10 7.001605607633385e-11 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/5902/7514/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/1104/5905/3837/81929/9631/79023/23636/53371/9688/8480 34 Varicella.zoster_virus R-HSA-6804757 Regulation of TP53 Degradation 34/4500 36/10654 3.852864670691088e-11 1.7519866711025274e-10 7.001605607633385e-11 11200/472/4194/8900/2475/5518/51230/7314/5515/117584/890/983/5519/10000/900/7157/6233/7874/253260/5170/1029/80196/64223/1616/208/79109/7311/5516/1017/207/7316/9099/5527/4193 34 Varicella.zoster_virus R-HSA-383280 Nuclear Receptor transcription pathway 45/4500 52/10654 4.17755720323023e-11 1.893464238866689e-10 7.567003819931723e-11 3174/126382/7068/5915/6097/7181/4929/5469/2104/9612/8856/29959/2101/7067/5914/9572/8431/7421/10062/7025/2516/5465/2099/7101/5467/2103/6257/5241/7182/3172/2063/9970/2908/9971/367/6095/5468/2100/9611/3164/6256/7376/6258/5916/9975 45 Varicella.zoster_virus R-HSA-194315 Signaling by Rho GTPases 260/4500 455/10654 4.550691864300369e-11 2.055911275910458e-10 8.216204013214772e-11 55839/11130/7984/71/6249/51517/5579/57522/392/9735/7531/55789/5526/29/51807/2909/10971/5578/9212/347688/613/1894/388/7533/2810/147841/348995/10381/57122/6280/1780/23122/3688/5048/57405/8655/10094/23279/5881/1432/2017/2491/7846/23365/79784/9475/1060/26230/9322/397/4628/11004/8976/1855/2885/6093/9184/8997/8826/10499/5518/26084/8874/23332/25909/10726/81930/5062/55746/9411/5879/5515/9181/85415/25/79682/1072/10403/4638/25936/4659/10093/1856/10006/4771/389/5594/29127/3619/64105/89839/7534/332/5528/6453/9828/6714/79902/3796/5519/81565/999/396/10810/85360/91687/57584/58504/83540/7410/5580/7409/1857/128239/9055/4649/23191/7514/54820/1729/6396/5600/91614/801/64946/9793/10109/5586/140735/2664/5500/4221/805/3831/220134/5170/84617/4928/9743/445328/5590/5903/653361/55055/5747/80776/1783/401541/2316/7532/3633/10382/7074/10627/79172/7277/10451/79980/58480/6232/5501/6279/55288/54821/10092/9183/4650/10163/1062/699/94134/22919/55845/5063/3895/57514/5529/51143/998/695/10788/6654/10097/57120/367/10383/5347/387/6655/60/84790/84643/5058/5924/7280/4629/7529/5595/64130/1778/5516/5905/81929/3984/27035/54908/55143/1495/1499/5525/4690/1058/991/79019/57580/4627/10928/348235/80152/10458/1063/8379/1027/9459/1080/23421/55920/79023/6242/1781/9824/10398/4085/5585/5216/10552/55166/23092/4637/1123/995/79003/23028/2/1742/90627/5527/10096/7454/701/23380/9928/29941/103910/57551/5296/5300/808/10095/4952 260 Varicella.zoster_virus R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 122/4500 185/10654 4.77589874432857e-11 2.1506950474460267e-10 8.594996042424932e-11 6158/6138/6227/6206/6234/6191/6128/6132/6129/10528/84135/27043/6224/6146/6154/88745/6202/6169/55272/6175/6218/5394/6173/6167/23481/51077/6156/117246/6143/6139/26168/11340/3921/10607/11103/6208/10813/9136/6203/6147/6222/1454/56902/51602/6134/6155/6231/6142/6207/10969/6233/6188/54881/1453/4691/23016/118460/200916/6122/6230/2091/55127/6194/8780/6136/6125/6232/134430/6160/92856/65083/6193/10200/6210/6229/6205/9790/140801/6235/6181/7311/6223/25873/51010/26354/51202/9045/6187/6168/6157/6137/22894/6144/9349/55813/4736/22803/51121/25879/6217/81887/6152/51065/6141/55781/6164/6209/11224/6165/6130/6204/6228/10199/6124/83732/6189/6135/6201/6161/54512/6133/9188 122 Varicella.zoster_virus R-HSA-5654716 Downstream signaling of activated FGFR4 27/4500 27/10654 7.486406168736504e-11 3.3496868626782564e-10 1.3386623716026815e-10 5295/4893/5335/9965/2264/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/2251/5781/6464/6654/2549/8822/8817/10817/2254/152831/26281/10818 27 Varicella.zoster_virus R-HSA-76066 RNA Polymerase III Transcription Initiation From Type 2 Promoter 27/4500 27/10654 7.486406168736504e-11 3.3496868626782564e-10 1.3386623716026815e-10 55718/2976/5435/9328/84265/9330/2972/2975/10622/661/55814/11128/9533/5434/10623/112495/9329/6908/51728/171568/10621/5440/5441/51082/55703/27297/5437 27 Varicella.zoster_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 58/4500 73/10654 8.02029442867318e-11 3.5771025630759615e-10 1.4295463417510634e-10 892/7321/4738/8239/9612/4609/4089/22938/23327/4088/5499/1030/7040/904/7314/5054/7027/6497/51592/50848/7323/6667/4092/11171/7050/5494/9958/9040/6233/7514/1025/57530/5500/4221/5590/3726/5501/1024/60436/8812/1874/142/905/4087/7048/7311/387/57154/51377/10273/64750/7316/1875/9611/5933/867/3065/56288 58 Varicella.zoster_virus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 33/4500 35/10654 8.660848214369823e-11 3.850491753904546e-10 1.538803068594035e-10 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/7884/4927/10482/8086/22916/81929/9631/79023/23636/4686/53371/9688/10189/8480 33 Varicella.zoster_virus R-HSA-74752 Signaling by Insulin receptor 61/4500 78/10654 8.767973796462798e-11 3.8857433078927195e-10 1.5528909313701867e-10 5295/3643/4893/2250/5291/535/50617/10312/9965/2264/3630/2885/8660/9846/2252/2253/3845/3265/2323/54106/51606/5290/3667/8823/9550/9114/5594/8074/57761/2260/2249/2248/2247/529/2246/2251/528/5781/5170/6464/2322/527/2263/208/6654/2549/5595/8822/8817/2254/152831/26281/10818/23545/2261/245972/2255/27006/5296/51382/2887 61 Varicella.zoster_virus R-HSA-72312 rRNA processing 132/4500 205/10654 9.35077828336277e-11 4.1309134441691223e-10 1.6508702498941602e-10 6158/6138/6227/6206/6234/6191/6128/6132/6129/55226/10528/84135/27043/6224/6146/6154/88745/6202/6169/55272/6175/6218/5394/6173/6167/23481/51077/6156/117246/6143/6139/26168/11340/3921/10607/11103/6208/10813/60528/9136/6203/51504/6147/27292/6222/1454/56902/51602/6134/6155/6231/6142/6207/10969/6233/6188/54881/1453/4691/23016/118460/200916/6122/6230/2091/55651/55127/6194/3028/8780/6136/6125/4839/6232/134430/6160/92856/65083/6193/10200/6210/6229/6205/9790/140801/6235/6181/7311/6223/25873/55505/51010/26354/51202/9045/51106/6187/6168/6157/6137/22894/6144/9349/55813/4736/22803/51121/25879/6217/81887/6152/51065/6141/55781/6164/54931/6209/11224/6165/6130/6204/6228/10199/6124/83732/6189/6135/6201/6161/54512/6133/9188 132 Varicella.zoster_virus R-HSA-1839124 FGFR1 mutant receptor activation 30/4500 31/10654 1.0255549904282707e-10 4.502121907666245e-10 1.7992192814531068e-010 5295/11052/2250/9530/613/6776/11064/2885/9846/2253/7750/8805/26127/5290/8074/2260/2249/399687/2247/2246/2251/6777/1523/9208/6774/6772/11160/8822/2254/26281 30 Varicella.zoster_virus R-HSA-5654733 Negative regulation of FGFR4 signaling 30/4500 31/10654 1.0255549904282707e-10 4.502121907666245e-10 1.7992192814531068e-010 9965/2264/2885/5518/2253/7314/5515/8823/5594/8074/2249/6714/2247/6233/2246/2251/5781/673/7311/5595/5516/8822/10253/8817/2254/7316/152831/26281/10818/867 30 Varicella.zoster_virus R-HSA-351202 Metabolism of polyamines 49/4500 59/10654 1.239523627324176e-10 5.424372989794827e-10 2.167785918105307e-10 5689/5682/143471/5705/5709/5695/5711/4946/5683/5699/5702/5696/5691/5718/1728/5700/122706/5707/23198/6723/9861/5698/5692/5713/5710/5719/196743/6303/5706/5714/5688/5687/5708/5704/5694/5684/5720/5690/5717/9491/10197/10213/5715/5701/5685/5686/5716/5693/5721 49 Varicella.zoster_virus R-HSA-5696400 Dual Incision in GG-NER 37/4500 41/10654 1.604321663262655e-10 6.998853255983332e-10 2.7970081629250237e-10 5982/9978/2965/2067/2967/6117/10714/7314/6118/404672/1643/5985/2068/5984/6233/5424/8451/54107/8450/5425/5111/2966/6119/5427/1642/142/2071/51426/7311/5983/56655/57804/2072/7316/5426/2968/5981 37 Varicella.zoster_virus R-HSA-109704 PI3K Cascade 39/4500 44/10654 1.7902617067770432e-10 7.761507275343951e-10 3.101793738449928e-10 5295/2250/5291/9965/2264/2885/8660/9846/2252/2253/2323/54106/5290/3667/8823/8074/57761/2260/2249/2248/2247/2246/2251/5781/5170/2322/2263/208/2549/8822/8817/2254/152831/26281/10818/2261/2255/27006/5296 39 Varicella.zoster_virus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 39/4500 44/10654 1.7902617067770432e-10 7.761507275343951e-10 3.101793738449928e-10 892/7321/8239/9612/4609/4089/22938/23327/4088/1030/904/7314/5054/7027/6497/51592/7323/6667/4092/7050/5494/6233/1025/4221/3726/1024/60436/8812/1874/142/905/4087/7311/64750/7316/1875/9611/5933/3065 39 Varicella.zoster_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 41/4500 47/10654 1.839202109371869e-10 7.900080445178859e-10 3.1571728517152735e-10 8454/79718/892/3091/9978/9759/9612/4609/22938/1387/6907/9794/388585/7314/79885/2648/9734/51564/55534/3280/84441/10013/7091/8850/3066/6233/10046/1024/10014/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/3516 41 Varicella.zoster_virus R-HSA-73762 RNA Polymerase I Transcription Initiation 41/4500 47/10654 1.839202109371869e-10 7.900080445178859e-10 3.1571728517152735e-10 2074/9112/5435/5928/2965/1107/2967/2648/30834/404672/8850/57459/2068/3066/9533/5434/9015/9219/5931/4331/9013/1108/2966/54815/2071/57504/6908/53615/5440/902/9014/25885/54700/5441/51082/7343/5437/3065/2968/1022/10919 41 Varicella.zoster_virus R-HSA-9020591 Interleukin-12 signaling 41/4500 47/10654 1.839202109371869e-10 7.900080445178859e-10 3.1571728517152735e-10 3593/5908/3313/6175/3936/5898/3717/3181/4001/3594/4282/5062/1072/3592/6627/9049/27250/9987/3185/3458/5478/302/552900/7297/6775/3595/4478/998/6648/3716/2939/6888/3586/829/6647/6950/4507/6845/375/5721/5034 41 Varicella.zoster_virus R-HSA-159227 Transport of the SLBP independent Mature mRNA 32/4500 34/10654 1.9434906593067195e-10 8.271685854854208e-10 3.305680518076256e-10 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/1977/6396/129401/4928/5903/55706/7175/4927/10482/8086/22916/81929/9631/79023/23636/4686/53371/9688/10189/8480 32 Varicella.zoster_virus R-HSA-165054 Rev-mediated nuclear export of HIV RNA 32/4500 34/10654 1.9434906593067195e-10 8.271685854854208e-10 3.305680518076256e-10 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/5902/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/1104/5905/81929/9631/79023/23636/53371/9688/8480 32 Varicella.zoster_virus R-HSA-4085377 SUMOylation of SUMOylation proteins 32/4500 34/10654 1.9434906593067195e-10 8.271685854854208e-10 3.305680518076256e-10 23165/348995/6613/57122/23511/23279/23225/9972/8021/55746/51588/10762/79902/9883/6396/129401/4928/5903/55706/7175/10210/4927/8086/7329/81929/9631/79023/23636/53371/9688/7341/8480 32 Varicella.zoster_virus R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 50/4500 61/10654 2.03604148751474e-10 8.639252026050386e-10 3.4525739509928404e-10 71/51517/10094/8976/2885/5879/25/1072/10093/10006/4771/5594/4644/4641/10810/7410/7409/23191/10109/2214/5747/2209/10451/6850/10092/4650/10163/55845/998/695/3326/10097/60/5058/63916/5595/3984/4690/4627/10458/919/10552/4620/917/3320/1398/10096/7454/10095/2212 50 Varicella.zoster_virus R-HSA-114452 Activation of BH3-only proteins 29/4500 30/10654 2.3601277238951704e-10 9.894109016689664e-10 3.9540625688776373e-10 7531/10971/7533/2810/1869/8655/90427/7159/637/23368/7027/7534/10000/7157/140735/572/7532/5366/8626/208/7161/7529/5533/27113/596/10018/207/5534/5599 29 Varicella.zoster_virus R-HSA-180786 Extension of Telomeres 29/4500 30/10654 2.3601277238951704e-10 9.894109016689664e-10 3.9540625688776373e-10 2237/1763/5982/5422/6117/10714/5558/6118/3978/5557/5985/5984/23649/8607/5424/55651/54107/5425/5111/6119/5427/55135/5983/56655/7015/57804/10856/5426/5981 29 Varicella.zoster_virus R-HSA-3928663 EPHA-mediated growth cone collapse 29/4500 30/10654 2.3601277238951704e-10 9.894109016689664e-10 3.9540625688776373e-10 2042/2045/285220/79784/2534/9475/4628/6093/284656/2046/2041/6714/1943/2043/7525/1942/10627/1945/4067/2044/387/4629/4627/10398/4637/1946/103910/1944/1969 29 Varicella.zoster_virus R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 29/4500 30/10654 2.3601277238951704e-10 9.894109016689664e-10 3.9540625688776373e-10 4893/817/1741/1739/6196/1740/6197/3845/3265/5923/818/5594/2902/6195/2906/801/4747/805/5170/2904/27330/816/5924/5595/815/1742/88/1385/808 29 Varicella.zoster_virus R-HSA-2980766 Nuclear Envelope Breakdown 44/4500 52/10654 3.308755258495613e-10 1.3829408206167292e-9 5.526757916806413e-10 23165/5579/91754/5578/348995/57122/23511/23279/23225/9663/4001/9972/8021/55746/10762/983/79902/9883/7444/2010/64900/23175/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/5347/7112/4000/81929/9631/79023/23636/7443/53371/9688/23592/8480 44 Varicella.zoster_virus R-HSA-168276 NS1 Mediated Effects on Host Pathways 36/4500 40/10654 3.4498347592488833e-10 1.4376027832571466e-9 5.745207925850458e-10 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/402569/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/4927/10898/3840/8086/3837/81929/9631/79023/23636/53371/9688/8480 36 Varicella.zoster_virus R-HSA-5696395 Formation of Incision Complex in GG-NER 38/4500 43/10654 3.7828944148450003e-10 1.5717025604534586e-9 6.281121678783993e-10 6613/9978/85015/2965/2067/2967/6612/6117/7334/7314/6118/404672/1643/2068/6233/5886/8451/8554/8450/4331/2966/6119/1642/142/2071/1069/7329/7311/902/7336/2072/7316/7341/10401/2968/5887/1022/7508 38 Varicella.zoster_virus R-HSA-1643713 Signaling by EGFR in Cancer 25/4500 25/10654 4.2240428880868165e-10 1.7241999625056127e-9 6.890559343447255e-10 5295/374/4893/5335/7039/2885/3845/3265/7314/1839/5290/2069/6233/255324/6464/6654/7311/1956/2549/11140/685/7316/1950/867/3320 25 Varicella.zoster_virus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 25/4500 25/10654 4.2240428880868165e-10 1.7241999625056127e-9 6.890559343447255e-10 11065/7321/8697/51529/29945/51434/9184/29882/7314/996/51433/119504/7324/64682/6233/246184/8881/10393/7311/25906/991/7316/4085/4751/701 25 Varicella.zoster_virus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 25/4500 25/10654 4.2240428880868165e-10 1.7241999625056127e-9 6.890559343447255e-10 9252/1848/1432/6196/5518/6197/51231/5515/1849/5594/5528/9261/5519/5598/4208/6195/5600/1846/5595/5516/1845/4205/466/2002/1385 25 Varicella.zoster_virus R-HSA-5654700 FRS-mediated FGFR2 signaling 25/4500 25/10654 4.2240428880868165e-10 1.7241999625056127e-9 6.890559343447255e-10 4893/2250/2885/2252/2253/3845/3265/8823/8074/2249/2248/2247/2246/2251/5781/2263/6654/8822/8817/10817/2254/26281/10818/2255/27006 25 Varicella.zoster_virus R-HSA-5654708 Downstream signaling of activated FGFR3 25/4500 25/10654 4.2240428880868165e-10 1.7241999625056127e-9 6.890559343447255e-10 5295/4893/2250/5335/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/5781/6464/6654/2549/8822/8817/10817/2254/26281/10818/2261 25 Varicella.zoster_virus R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 25/4500 25/10654 4.2240428880868165e-10 1.7241999625056127e-9 6.890559343447255e-10 5982/6117/10714/7314/6118/3978/5985/5984/6233/5424/7515/54107/5425/5111/6119/5427/51426/7311/3980/5983/56655/57804/7316/5426/5981 25 Varicella.zoster_virus R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 31/4500 33/10654 4.353199371228355e-10 1.7665890471612744e-9 7.059962260560063e-10 23165/348995/57122/23511/23279/23225/9972/8021/55746/3303/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/3304/81929/9631/79023/23636/53371/9688/8480 31 Varicella.zoster_virus R-HSA-180746 Nuclear import of Rev protein 31/4500 33/10654 4.353199371228355e-10 1.7665890471612744e-9 7.059962260560063e-10 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4869/4927/5901/8086/1104/3837/81929/9631/79023/23636/53371/9688/8480 31 Varicella.zoster_virus R-HSA-5654732 Negative regulation of FGFR3 signaling 28/4500 29/10654 5.424949734108488e-10 2.187371855081508e-9 8.74157052626451e-10 2250/2885/5518/2253/7314/5515/8823/5594/8074/2249/6714/2247/6233/2246/5781/673/7311/5595/5516/8822/10253/8817/2254/7316/26281/10818/2261/867 28 Varicella.zoster_virus R-HSA-8863795 Downregulation of ERBB2 signaling 28/4500 29/10654 5.424949734108488e-10 2.187371855081508e-9 8.74157052626451e-10 26469/2064/145957/4145/9542/7314/1839/2065/2069/9101/10000/6233/5782/10193/3084/208/10718/7311/1956/11140/8065/685/10273/207/7316/1950/3320/2066 28 Varicella.zoster_virus R-HSA-400253 Circadian Clock 55/4500 70/10654 5.437091932043576e-10 2.187371855081508e-9 8.74157052626451e-10 8454/79718/5936/28999/3091/5469/1387/150094/6907/5499/10499/23054/1386/23411/9572/85441/7314/96764/5054/8945/1454/5465/4208/6604/80205/6233/8864/1453/5500/1374/4783/406/4209/5501/8553/2908/1390/7311/23373/6095/8841/8204/4862/6500/200186/6720/7316/9611/2033/6256/10498/1385/8648/551/10891 55 Varicella.zoster_virus R-HSA-5358351 Signaling by Hedgehog 100/4500 149/10654 6.131490046487996e-10 2.459643708303805e-9 9.829672488320139e-10 8454/5689/5682/22873/1452/51684/143471/10381/5705/8452/5709/9978/5695/5711/7846/5683/408/5699/6400/5702/83737/6868/6469/5696/5691/7314/5718/8945/5700/122706/5707/5567/10956/23198/112/5573/2737/5727/8650/9861/2932/5698/5692/5713/5710/5719/6233/23322/115/84617/54903/10382/23288/79809/5568/409/79577/7277/5706/84447/5714/5566/5688/5687/5708/5577/5704/7311/10383/84790/5694/7280/57154/5684/5720/2735/5575/6608/5690/5717/9491/6500/114/7289/10197/64750/7316/10213/2778/7415/5715/5701/5576/5685/5686/5716/8481/5693/5721/5034 100 Varicella.zoster_virus R-HSA-73893 DNA Damage Bypass 41/4500 48/10654 7.44953769212564e-10 2.979815076850256e-9 1.1908475273191346e-9 56852/5982/9978/25898/57599/6117/10714/55666/7314/51514/6118/9636/11201/51455/5985/5984/6233/5424/8451/54107/7706/8450/5425/5111/6119/5427/1642/9246/51426/7311/5983/56655/57804/7320/7316/5426/9100/7415/7398/5981/5980 41 Varicella.zoster_virus R-HSA-448424 Interleukin-17 signaling 56/4500 72/10654 7.643042772752334e-10 3.048482203074931e-9 1.2182895246793194e-9 8454/3605/3725/9252/4790/1848/1432/3654/6196/5518/1386/6197/7334/3551/51231/7314/5515/8945/5601/5606/1849/5594/8517/5528/9261/5519/5598/4208/6195/10454/6233/2353/5600/5608/1846/79155/5602/7189/112744/7311/6416/5595/5516/1147/1845/6885/5604/6500/7316/4205/466/23291/2002/5609/1385/5599 56 Varicella.zoster_virus R-HSA-5619084 ABC transporter disorders 59/4500 77/10654 7.698224915852887e-10 3.0530460177643835e-9 1.2201133987446263e-9 5244/5689/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/5696/5691/7314/5718/5700/122706/5707/10956/79139/91445/23198/9861/5698/5692/5713/5710/5719/6233/5706/19/335/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/1244/7316/10213/7415/5715/5701/5685/5686/5716/5693/5721 59 Varicella.zoster_virus R-HSA-9009391 Extra-nuclear estrogen signaling 59/4500 77/10654 7.698224915852887e-10 3.0530460177643835e-9 1.2201133987446263e-9 5295/374/4893/857/2770/7039/2782/3845/3265/8877/2773/2787/1839/5290/4316/5594/2069/4313/6714/2099/10000/595/2783/2784/2771/7514/2353/255324/801/805/5170/5590/6464/5747/3315/4318/8503/208/1956/858/3480/5595/596/685/2309/59345/207/1027/2100/1950/55970/4314/3320/4846/2002/1385/5296/808/3276 59 Varicella.zoster_virus R-HSA-3899300 SUMOylation of transcription cofactors 39/4500 45/10654 7.935558507115877e-10 3.138254865703616e-9 1.2541660977400973e-9 1912/6045/80012/6613/28996/9612/1911/1387/57332/4152/115426/10499/6612/11315/3622/51588/1655/84733/10155/9063/7690/6015/8554/8535/4869/10210/10521/1616/7329/25942/648/1487/8204/7341/10401/2033/6294/8648/10891 39 Varicella.zoster_virus R-HSA-168253 Host Interactions with Influenza Factors 37/4500 42/10654 7.969594232371822e-10 3.142811736833634e-9 1.2559871968947566e-9 23165/348995/57122/23511/23279/23225/3836/9972/8021/7040/55746/402569/8106/9636/10762/79902/9883/5610/6396/129401/4928/3838/5903/55706/7175/4927/10898/3840/8086/3837/81929/9631/79023/23636/53371/9688/8480 37 Varicella.zoster_virus R-HSA-69190 DNA strand elongation 30/4500 32/10654 9.73181101185566e-10 3.826931879591691e-9 1.5293876460440328e-9 2237/1763/5982/5422/4174/84515/6117/10714/5558/6118/3978/5557/5985/4175/5984/23649/5424/4172/8318/4173/5425/5111/6119/51659/5983/4176/57804/9837/4171/5981 30 Varicella.zoster_virus R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 24/4500 24/10654 1.0031630004549388e-9 3.914270437746543e-9 1.5642914583061892e-9 2237/1763/5982/5422/6117/10714/5558/6118/3978/5557/5985/5984/23649/5424/54107/5425/5111/6119/5427/5983/56655/57804/5426/5981 24 Varicella.zoster_virus R-HSA-982772 Growth hormone receptor signaling 24/4500 24/10654 1.0031630004549388e-9 3.914270437746543e-9 1.5642914583061892e-9 5777/5770/9021/6776/3717/5618/6868/8660/1154/3667/2690/5594/5617/8835/6777/6774/6772/8651/1442/4067/2689/5595/25970/2688 24 Varicella.zoster_virus R-HSA-373760 L1CAM interactions 83/4500 119/10654 1.003802877301764e-9 3.914270437746543e-9 1.5642914583061892e-9 9252/6711/71/7430/1459/51807/347688/1785/1460/10381/4684/3688/1457/285643/5605/7846/3690/1808/6456/1741/1739/3786/6709/163/6196/1759/6197/6334/3312/100133941/5879/6331/6900/6326/161/5594/284217/2260/3672/8650/6714/6195/214/7410/51332/3685/1213/1211/1175/1173/84617/6712/3674/10382/7277/3678/4478/160/3912/3785/26052/6710/27330/6386/2048/3897/10383/24137/1956/60/84790/5058/7280/5595/6328/5604/10048/3915/57731/3673/6708/1742/287 83 Varicella.zoster_virus R-HSA-112382 Formation of RNA Pol II elongation complex 49/4500 61/10654 1.1950393895875893e-9 4.634097188511874e-9 1.851961627138662e-9 5431/5435/5433/2965/5439/2967/11198/904/51497/80349/404672/5438/2068/1025/23168/55677/7936/6829/123169/25920/2963/5434/5436/9646/79577/4331/2966/2962/8812/905/2071/5432/22916/55840/6917/5440/902/6830/5430/6749/5441/4686/9150/54623/5437/6827/2968/1022/8178 49 Varicella.zoster_virus R-HSA-75955 RNA Polymerase II Transcription Elongation 49/4500 61/10654 1.1950393895875893e-9 4.634097188511874e-9 1.851961627138662e-9 5431/5435/5433/2965/5439/2967/11198/904/51497/80349/404672/5438/2068/1025/23168/55677/7936/6829/123169/25920/2963/5434/5436/9646/79577/4331/2966/2962/8812/905/2071/5432/22916/55840/6917/5440/902/6830/5430/6749/5441/4686/9150/54623/5437/6827/2968/1022/8178 49 Varicella.zoster_virus R-HSA-69205 G1/S-Specific Transcription 27/4500 28/10654 1.2453978682037182e-9 4.815998404466456e-9 1.9246562768565993e-9 5422/1869/4998/5928/990/8900/6241/7027/898/5934/1876/983/7298/1719/26271/8318/286826/5111/91750/1874/81620/55957/1875/5933/3065/7083/132660 27 Varicella.zoster_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 59/4500 78/10654 1.8611944633206354e-9 7.177423952474052e-9 2.8683718102935065e-9 3443/4790/7321/4792/177/3093/1387/64135/83737/1540/3551/7314/3445/8737/29110/4214/9636/841/8517/3444/7323/5970/23586/7128/3451/3448/3661/3439/51191/6233/55593/8772/3452/4791/3446/3665/351/7706/843/3440/9246/7189/7311/5094/3456/1147/3441/7186/57506/3449/7316/4793/3146/7322/2033/6288/54941/6285/5300 59 Varicella.zoster_virus R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF) 45/4500 55/10654 1.8767838317948315e-9 7.217603937150372e-9 2.8844292615666546e-9 79718/10484/3638/5469/1387/6907/4801/6309/10499/23054/85441/31/96764/8720/5465/2222/3157/6667/3156/6604/80205/10654/6319/6721/10802/9453/4800/57678/32/1595/5901/4047/9871/3837/4802/6720/2194/22937/4597/1717/6256/10498/51360/2224/8648 45 Varicella.zoster_virus R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 29/4500 31/10654 2.171143235916501e-9 8.28119114027168e-9 3.3094791919348453e-9 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/3837/81929/9631/79023/23636/53371/9688/8480 29 Varicella.zoster_virus R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 29/4500 31/10654 2.171143235916501e-9 8.28119114027168e-9 3.3094791919348453e-9 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/7514/6396/129401/4928/5903/55706/7175/4927/5901/8086/81929/9631/79023/23636/53371/9688/8480 29 Varicella.zoster_virus R-HSA-5654687 Downstream signaling of activated FGFR1 29/4500 31/10654 2.171143235916501e-9 8.28119114027168e-9 3.3094791919348453e-9 5295/4893/2250/5335/2885/2253/3845/3265/5290/23768/8074/2260/2249/2248/2247/2246/2251/5781/6464/23767/6654/2549/8822/10817/2254/26281/10818/2255/27006 29 Varicella.zoster_virus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 23/4500 23/10654 2.3820919941560014e-9 9.011925267863897e-9 3.601508363721811e-9 11065/7321/8697/51529/29945/51434/29882/7314/996/983/51433/119504/7324/64682/6233/246184/8881/891/10393/7311/25906/991/7316 23 Varicella.zoster_virus R-HSA-5654695 PI-3K cascade:FGFR2 23/4500 23/10654 2.3820919941560014e-9 9.011925267863897e-9 3.601508363721811e-9 5295/2250/2885/2252/2253/5290/8823/8074/2249/2248/2247/2246/2251/5781/2263/2549/8822/8817/2254/26281/10818/2255/27006 23 Varicella.zoster_virus R-HSA-5654699 SHC-mediated cascade:FGFR2 23/4500 23/10654 2.3820919941560014e-9 9.011925267863897e-9 3.601508363721811e-9 4893/2250/2885/2252/2253/3845/3265/8823/8074/2249/2248/2247/2246/2251/6464/2263/6654/8822/8817/2254/26281/2255/27006 23 Varicella.zoster_virus R-HSA-1538133 G0 and Early G1 26/4500 27/10654 2.8552088899951936e-9 1.0743589246450916e-8 4.2935472030002915e-9 9134/1869/4609/5928/990/8900/7027/7153/898/5934/993/890/983/1859/286826/5111/91750/1874/55957/1017/4605/4149/1875/5933/3065/132660 26 Varicella.zoster_virus R-HSA-912526 Interleukin receptor SHC signaling 26/4500 27/10654 2.8552088899951936e-9 1.0743589246450916e-8 4.2935472030002915e-9 5295/5777/1437/5291/3558/3717/3563/2885/9846/5290/1439/3718/3567/3562/6464/1438/8503/3636/6654/3716/5293/3561/3568/3560/5296/3559 26 Varicella.zoster_virus R-HSA-187687 Signalling to ERKs 31/4500 34/10654 2.9253522727752596e-9 1.0977934873102857e-8 4.387200635458087e-9 4893/5605/5898/1432/5603/2885/3845/3265/1399/5899/5594/9261/6714/4914/5600/6300/6464/673/2889/6654/5900/7529/5595/25759/5604/57498/10818/53358/4803/1398/5906 31 Varicella.zoster_virus R-HSA-5685942 HDR through Homologous Recombination (HRR) 52/4500 67/10654 3.5617113909938214e-9 1.3330158449939342e-8 5.3272387109544954e-9 83990/9156/1763/7486/5982/472/4683/84126/672/6117/10714/348654/83695/7314/6118/5888/116028/5985/5984/6233/5884/5810/5424/80010/54107/580/11073/5425/641/5111/6119/3364/10524/5427/144715/1111/79728/51426/7311/5983/56655/5883/10111/57804/675/545/7316/5426/10635/5932/7156/5981 52 Varicella.zoster_virus R-HSA-4090294 SUMOylation of intracellular receptors 28/4500 30/10654 4.833245787709471e-9 1.8040671442894172e-8 7.20973900221227e-9 7068/6613/7181/4929/9759/8856/7067/6612/5914/7421/10062/51588/2516/5465/2099/9063/8554/5241/2908/9971/7329/367/6095/5468/7341/10401/6256/7376 28 Varicella.zoster_virus R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 40/4500 48/10654 5.384424553139222e-9 2.0044417803152943e-8 8.010512317652737e-9 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/8812/905/2071/5432/22916/6917/5440/902/5430/6749/5441/4686/9150/5437/6827/2968/1022/8178 40 Varicella.zoster_virus R-HSA-1250196 SHC1 events in ERBB2 signaling 22/4500 22/10654 5.655739634181912e-9 2.0777401392941973e-8 8.303440460156271e-9 4893/5578/2064/145957/9542/2885/3845/3265/1839/2065/2069/5580/6464/5782/3084/6654/10718/1956/685/1950/2066/5581 22 Varicella.zoster_virus R-HSA-198753 ERK/MAPK targets 22/4500 22/10654 5.655739634181912e-9 2.0777401392941973e-8 8.303440460156271e-9 9252/1848/1432/6196/5518/6197/51231/5515/1849/5594/5528/5519/5598/4208/6195/5600/1846/5595/5516/1845/4205/2002 22 Varicella.zoster_virus R-HSA-5654712 FRS-mediated FGFR4 signaling 22/4500 22/10654 5.655739634181912e-9 2.0777401392941973e-8 8.303440460156271e-9 4893/9965/2264/2885/2253/3845/3265/8823/8074/2249/2247/2246/2251/5781/6654/8822/8817/10817/2254/152831/26281/10818 22 Varicella.zoster_virus R-HSA-5655332 Signaling by FGFR3 in disease 22/4500 22/10654 5.655739634181912e-9 2.0777401392941973e-8 8.303440460156271e-9 5295/4893/2250/5335/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/6654/2549/8822/8817/2254/26281/10818/2261 22 Varicella.zoster_virus R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 22/4500 22/10654 5.655739634181912e-9 2.0777401392941973e-8 8.303440460156271e-9 5295/4893/2250/5335/2885/2253/3845/3265/5290/8823/8074/2249/2247/2246/6654/2549/8822/8817/2254/26281/10818/2261 22 Varicella.zoster_virus R-HSA-2559585 Oncogene Induced Senescence 30/4500 33/10654 6.351792741812795e-9 2.321231064809074e-8 9.276522880024198e-9 27327/5925/2114/1869/4194/1031/192669/1032/1030/4343/7314/7027/5594/6667/7157/6233/26523/1019/1029/1870/7311/2113/5595/57690/192670/7316/1871/1021/23112/4193 30 Varicella.zoster_virus R-HSA-5654726 Negative regulation of FGFR1 signaling 30/4500 33/10654 6.351792741812795e-9 2.321231064809074e-8 9.276522880024198e-9 2250/2885/5518/2253/7314/5515/5594/8074/2260/2249/6714/2248/2247/6233/2246/2251/5781/673/7311/5595/5516/8822/10253/2254/7316/26281/10818/867/2255/27006 30 Varicella.zoster_virus R-HSA-6803529 FGFR2 alternative splicing 25/4500 26/10654 6.536516607297341e-9 2.3825005701793963e-8 9.521379144888254e-9 54845/5431/5435/5433/5439/7072/7073/5438/3185/4670/5725/2963/5434/5436/2962/80004/5432/22916/5440/5430/3178/5441/4686/5437/3187 25 Varicella.zoster_virus R-HSA-9006931 Signaling by Nuclear Receptors 175/4500 299/10654 6.6633277816620875e-9 2.422397287291738e-8 9.680821612612135e-9 5295/374/3725/4893/857/79718/7031/5160/5165/2770/10901/7039/27327/10274/5915/1381/8050/5431/5435/5433/1509/5469/1105/9612/4609/55818/1387/6907/8312/2782/5439/192669/10499/1386/5914/4343/3845/904/1071/7392/3265/8877/2773/10062/2787/6387/1839/5290/4316/344/5594/2069/1737/5481/5438/348/4313/865/1655/6667/6714/2099/8850/5467/10000/5162/595/2783/2784/2771/7514/1025/2353/6257/255324/5164/26523/801/29116/2957/805/5105/5170/2963/3838/5434/5590/6464/112724/1374/5241/6319/5747/5436/3315/4318/5885/19/57678/7033/2962/8503/10524/5346/8243/4602/208/3326/6908/1956/5536/3169/858/5432/3480/10728/5595/7528/3727/27161/2354/596/5440/8841/685/347/2309/59345/8204/5430/207/5451/2625/57690/1027/5441/10735/6720/192670/2100/1950/9611/55970/2874/2194/4314/7391/2958/5163/5437/3320/1382/2033/221656/4846/9126/3065/2002/2066/861/23028/6256/23112/7376/10498/1385/1738/5296/808/6258/3276/5916/8202/8648/2288 175 Varicella.zoster_virus R-HSA-2426168 Activation of gene expression by SREBF (SREBP) 36/4500 42/10654 6.934513795821574e-9 2.5079226059499788e-8 1.0022613340020276e-8 79718/5469/1387/6907/4801/6309/10499/23054/85441/31/96764/5465/2222/3157/6667/3156/6604/80205/10654/6319/6721/9453/4800/57678/32/1595/4047/4802/6720/2194/4597/1717/6256/10498/2224/8648 36 Varicella.zoster_virus R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 36/4500 42/10654 6.934513795821574e-9 2.5079226059499788e-8 1.0022613340020276e-8 83990/9156/1763/7486/5982/472/4683/84126/672/6117/83695/6118/5888/116028/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/1111/79728/5983/5883/10111/675/545/10635/5932/7156 36 Varicella.zoster_virus R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 34/4500 39/10654 7.309081909694951e-9 2.6365577121276877e-8 1.0536688187510744e-8 83990/9156/1763/7486/5982/472/4683/84126/672/6117/83695/6118/5888/116028/5985/5984/5884/5810/80010/580/11073/641/6119/3364/10524/144715/1111/5983/5883/10111/675/545/5932/7156 34 Varicella.zoster_virus R-HSA-983169 Class I MHC mediated antigen processing & presentation 210/4500 371/10654 1.0327338798595322e-8 3.7157126192884206e-8 1.4849401962169079e-8 8454/8773/5689/11065/55070/5682/3107/7321/9021/8697/10484/9817/7174/6478/811/143471/5705/57674/9690/8452/5709/9978/5695/567/4734/7337/7704/3106/3093/5711/23327/51465/10616/5683/3309/89910/25898/5699/7328/7428/5702/22954/83737/51529/10075/29945/8924/56658/51434/10425/25793/3133/29882/7334/92591/84961/3551/7332/5696/5691/9820/55658/7314/996/5718/8945/64410/10952/5700/122706/5707/23198/10533/8517/6810/6477/7323/22872/4008/11059/51433/9861/10134/6502/5698/27246/5692/5713/79654/5710/9040/7324/5719/64682/8925/51191/6233/3685/6047/868/6396/5930/11275/29116/23608/55585/51132/899/3135/23352/653361/246184/151636/10802/10193/6890/821/81559/2209/5706/26263/9554/8881/29927/7317/80196/84078/5714/26272/8651/5688/5687/26270/63893/118424/5708/55008/2923/695/63891/9246/10393/9902/5704/9520/4012/7327/51343/7311/9871/9320/57520/5694/8673/3105/997/7325/140691/57154/1147/5684/6737/8065/5720/7319/54850/26046/991/10273/7320/5690/5717/9491/6500/26259/10197/7099/7336/4615/64750/23376/7316/10213/114907/54926/25831/7322/5715/5701/9341/23291/5685/5686/55521/114609/55294/8453/80176/8139/948/5716/7064/3134/80204/27338/7097/23014/90678/5693/5721 210 Varicella.zoster_virus R-HSA-5218920 VEGFR2 mediated vascular permeability 27/4500 29/10654 1.0734586947907339e-8 3.842431635712473e-8 1.535581938567042e-8 857/2475/5062/5879/57761/1500/10000/3728/7410/7409/801/253260/805/5170/10451/64223/1003/5063/208/79109/5058/1495/1499/207/3320/4846/808 27 Varicella.zoster_virus R-HSA-72086 mRNA Capping 27/4500 29/10654 1.0734586947907339e-8 3.842431635712473e-8 1.535581938567042e-8 5431/5435/5433/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/22916/5440/902/5430/5441/4686/5437/2968/1022 27 Varicella.zoster_virus R-HSA-389513 CTLA4 inhibitory signaling 21/4500 21/10654 1.3426541533881733e-8 4.781492852372168e-8 1.9108665448327927e-008 5526/941/2534/5518/5515/5528/6714/5519/10000/7525/3932/5781/1493/4067/5529/208/5516/5525/207/942/5527 21 Varicella.zoster_virus R-HSA-6807004 Negative regulation of MET activity 21/4500 21/10654 1.3426541533881733e-8 4.781492852372168e-8 1.9108665448327927e-008 5770/3082/6456/30011/2885/7314/8027/2060/9101/9146/6455/6233/4233/5795/5771/7311/26018/7316/867/10254/6457 21 Varicella.zoster_virus R-HSA-9006115 Signaling by NTRK2 (TRKB) 24/4500 25/10654 1.4941372079964996e-8 5.29394807706374e-8 2.1156631585309776e-8 5295/627/4893/5335/2534/2885/3845/3265/5879/5290/6714/4909/5781/4908/6464/2904/7074/6654/2549/1020/4915/10817/10818/8851 24 Varicella.zoster_virus R-HSA-9006335 Signaling by Erythropoietin 24/4500 25/10654 1.4941372079964996e-8 5.29394807706374e-8 2.1156631585309776e-8 5295/4893/5335/5291/6776/3717/2885/2056/8660/3845/3265/1399/5290/5336/5294/2057/7409/6777/6464/2889/4067/6654/5293/2549 24 Varicella.zoster_virus R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 31/4500 35/10654 1.5184072199430793e-8 5.36632020010263e-8 2.1445858136437897e-8 23165/91754/348995/57122/23511/23279/23225/9972/8021/55746/10762/983/79902/9883/6396/129401/4928/5903/55706/7175/9133/891/4927/8086/81929/9631/79023/23636/53371/9688/8480 31 Varicella.zoster_virus R-HSA-8986944 Transcriptional Regulation by MECP2 48/4500 62/10654 1.659774707419196e-8 5.851124978679792e-8 2.3383322565980168e-8 627/2290/79718/5770/817/9212/27327/6657/28996/9612/4988/6907/192669/4204/3654/4343/814/818/54487/4208/3066/26523/801/2891/805/2904/3930/54715/4233/6515/5566/816/25942/27161/815/8841/5468/57690/192670/9611/2874/2903/3064/5728/3065/23112/1385/808 48 Varicella.zoster_virus R-HSA-167169 HIV Transcription Elongation 38/4500 46/10654 2.1217958162806133e-8 7.423626464981794e-8 2.9667637056555207e-8 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/4686/9150/5437/6827/2968/1022/8178 38 Varicella.zoster_virus R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 38/4500 46/10654 2.1217958162806133e-8 7.423626464981794e-8 2.9667637056555207e-8 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/4686/9150/5437/6827/2968/1022/8178 38 Varicella.zoster_virus R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 38/4500 46/10654 2.1217958162806133e-8 7.423626464981794e-8 2.9667637056555207e-8 5431/5435/5433/2965/5439/2967/11198/904/51497/404672/5438/2068/1025/7936/6829/25920/2963/5434/5436/4331/2966/2962/2071/5432/22916/6917/5440/902/5430/6749/5441/4686/9150/5437/6827/2968/1022/8178 38 Varicella.zoster_virus R-HSA-350054 Notch-HLH transcription pathway 26/4500 28/10654 2.3782752173284428e-8 8.279481803966349e-8 3.308796076083672e-8 79718/9759/9612/22938/1387/6907/4853/9794/79885/2648/9734/51564/55534/84441/10013/4854/8850/3066/10046/10014/4855/4851/8841/9611/3065/3516 26 Varicella.zoster_virus R-HSA-75067 Processing of Capped Intronless Pre-mRNA 26/4500 28/10654 2.3782752173284428e-8 8.279481803966349e-8 3.308796076083672e-8 51585/81608/1477/53981/134353/11051/8106/1478/23283/6636/10914/6635/7884/6637/10898/51692/22916/1479/79869/29894/4686/8189/10978/6634/55339/6628 26 Varicella.zoster_virus R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 20/4500 20/10654 3.1870054167700524e-8 1.0904557749536747e-7 4.357876343880619e-8 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Varicella.zoster_virus R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 20/4500 20/10654 3.1870054167700524e-8 1.0904557749536747e-7 4.357876343880619e-8 11065/7321/8697/51529/29945/51434/9184/29882/996/51433/119504/7324/64682/246184/8881/10393/25906/991/4085/701 20 Varicella.zoster_virus R-HSA-5654706 FRS-mediated FGFR3 signaling 20/4500 20/10654 3.1870054167700524e-8 1.0904557749536747e-7 4.357876343880619e-8 4893/2250/2885/2253/3845/3265/8823/8074/2249/2247/2246/5781/6654/8822/8817/10817/2254/26281/10818/2261 20 Varicella.zoster_virus R-HSA-5654719 SHC-mediated cascade:FGFR4 20/4500 20/10654 3.1870054167700524e-8 1.0904557749536747e-7 4.357876343880619e-8 4893/9965/2264/2885/2253/3845/3265/8823/8074/2249/2247/2246/2251/6464/6654/8822/8817/2254/152831/26281 20 Varicella.zoster_virus R-HSA-5654720 PI-3K cascade:FGFR4 20/4500 20/10654 3.1870054167700524e-8 1.0904557749536747e-7 4.357876343880619e-8 5295/9965/2264/2885/2253/5290/8823/8074/2249/2247/2246/2251/5781/2549/8822/8817/2254/152831/26281/10818 20 Varicella.zoster_virus R-HSA-69186 Lagging Strand Synthesis 20/4500 20/10654 3.1870054167700524e-8 1.0904557749536747e-7 4.357876343880619e-8 2237/1763/5982/5422/6117/10714/5558/6118/3978/5557/5985/5984/23649/5424/5425/5111/6119/5983/57804/5981 20 Varicella.zoster_virus R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 20/4500 20/10654 3.1870054167700524e-8 1.0904557749536747e-7 4.357876343880619e-8 22938/1387/4088/4853/9794/388585/2648/55534/3280/84441/8850/2324/10046/59/4855/23493/4851/23462/2033/3516 20 Varicella.zoster_virus R-HSA-5627123 RHO GTPases activate PAKs 23/4500 24/10654 3.409745884928047e-8 1.1638154658580814e-7 4.651049592103629e-8 2017/79784/4628/5062/5879/4638/4659/4771/801/5500/805/2316/10627/5063/998/5058/4629/3984/4627/10398/4637/103910/808 23 Varicella.zoster_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 48/4500 63/10654 4.11502568374057e-8 1.4011160620736185e-7 5.599393099826707e-8 55718/4790/5435/4792/3428/1387/84265/22954/1660/3551/7314/8737/29110/8517/6778/5970/3661/6233/10622/661/11128/4791/9533/3665/5434/10623/7098/9208/5591/7311/51728/171568/10621/2547/1147/5440/6737/1499/7520/5441/51082/4615/7316/55703/27297/4793/5437/2033 48 Varicella.zoster_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 45/4500 58/10654 4.169686672436662e-8 1.4026223119811035e-7 5.605412647790568e-8 8454/79718/892/182/9978/9759/9612/4609/22938/1387/6907/6868/9794/388585/7314/79885/2648/9734/51564/55534/3280/84441/10013/102/5664/8850/3066/6233/5663/10046/1024/10014/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/54567/3516 45 Varicella.zoster_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 45/4500 58/10654 4.169686672436662e-8 1.4026223119811035e-7 5.605412647790568e-8 8454/79718/892/182/9978/9759/9612/4609/22938/1387/6907/6868/9794/388585/7314/79885/2648/9734/51564/55534/3280/84441/10013/102/5664/8850/3066/6233/5663/10046/1024/10014/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/54567/3516 45 Varicella.zoster_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 45/4500 58/10654 4.169686672436662e-8 1.4026223119811035e-7 5.605412647790568e-8 8454/79718/892/182/9978/9759/9612/4609/22938/1387/6907/6868/9794/388585/7314/79885/2648/9734/51564/55534/3280/84441/10013/102/5664/8850/3066/6233/5663/10046/1024/10014/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/54567/3516 45 Varicella.zoster_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 45/4500 58/10654 4.169686672436662e-8 1.4026223119811035e-7 5.605412647790568e-8 8454/79718/892/182/9978/9759/9612/4609/22938/1387/6907/6868/9794/388585/7314/79885/2648/9734/51564/55534/3280/84441/10013/102/5664/8850/3066/6233/5663/10046/1024/10014/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/54567/3516 45 Varicella.zoster_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 45/4500 58/10654 4.169686672436662e-8 1.4026223119811035e-7 5.605412647790568e-8 8454/79718/892/182/9978/9759/9612/4609/22938/1387/6907/6868/9794/388585/7314/79885/2648/9734/51564/55534/3280/84441/10013/102/5664/8850/3066/6233/5663/10046/1024/10014/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/54567/3516 45 Varicella.zoster_virus R-HSA-8939211 ESR-mediated signaling 134/4500 223/10654 4.505350679621453e-8 1.5118917184498917e-7 6.042094787953874e-8 5295/374/3725/4893/857/7031/2770/7039/27327/10274/5431/5435/5433/1509/5469/1105/4609/1387/8312/2782/5439/192669/10499/1386/4343/3845/904/7392/3265/8877/2773/2787/6387/1839/5290/4316/5594/2069/5481/5438/4313/865/1655/6667/6714/2099/8850/10000/595/2783/2784/2771/7514/1025/2353/255324/26523/801/2957/805/5170/2963/3838/5434/5590/6464/5241/5747/5436/3315/4318/5885/57678/7033/2962/8503/10524/8243/4602/208/3326/6908/1956/5536/3169/858/5432/3480/10728/5595/7528/3727/27161/2354/596/5440/685/2309/59345/8204/5430/207/5451/2625/57690/1027/5441/10735/192670/2100/1950/55970/4314/7391/2958/5437/3320/2033/4846/9126/3065/2002/2066/861/23028/23112/10498/1385/5296/808/3276/8202/8648/2288 134 Varicella.zoster_virus R-HSA-388841 Costimulation by the CD28 family 52/4500 70/10654 4.90179027192172e-8 1.6409830262836263e-7 6.557992790908778e-8 5295/5777/5526/941/3115/2534/2885/2475/5518/3127/5062/5879/5515/5290/57761/5528/9020/6714/5519/29126/10000/1445/916/7525/7409/3932/5781/1493/253260/5170/3123/3122/920/64223/8503/4067/5063/5529/998/208/79109/5058/5516/9402/5525/207/919/915/917/942/5527/5296 52 Varicella.zoster_virus R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 25/4500 27/10654 5.255286307357368e-8 1.7426080012044858e-7 6.96412487285762e-8 5431/5435/5433/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/5440/902/5430/5441/5437/2968/1022 25 Varicella.zoster_virus R-HSA-354192 Integrin alphaIIb beta3 signaling 25/4500 27/10654 5.255286307357368e-8 1.7426080012044858e-7 6.96412487285762e-8 5770/5908/2244/3690/2885/9564/7094/10125/6714/2335/1445/2266/2243/5170/6464/5747/3674/6850/6654/7450/207/54518/1398/10235/5906 25 Varicella.zoster_virus R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 25/4500 27/10654 5.255286307357368e-8 1.7426080012044858e-7 6.96412487285762e-8 5431/5435/5433/2965/5439/2967/404672/5438/2068/6829/2963/5434/5436/4331/2966/2962/2071/5432/5440/902/5430/5441/5437/2968/1022 25 Varicella.zoster_virus R-HSA-9006921 Integrin signaling 25/4500 27/10654 5.255286307357368e-8 1.7426080012044858e-7 6.96412487285762e-8 5770/5908/2244/3690/2885/9564/7094/10125/6714/2335/1445/2266/2243/5170/6464/5747/3674/6850/6654/7450/207/54518/1398/10235/5906 25 Varicella.zoster_virus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 70/4500 102/10654 5.813173214806378e-8 1.9230307601586978e-7 7.685162893108958e-8 8454/8792/7124/5689/5682/356/143471/5705/5709/5695/7133/5711/5683/5699/5702/60401/958/5696/5691/7314/5718/8945/5700/122706/5707/23198/9020/8741/9861/5698/5692/5713/5710/9040/5719/6233/4791/959/8600/330/5706/5714/5688/5687/5708/5704/7311/5971/5694/1147/5684/5720/7186/5690/5717/9491/6500/10197/7316/10213/5715/7132/5701/329/23291/5685/5686/5716/5693/5721 70 Varicella.zoster_virus R-HSA-5628897 TP53 Regulates Metabolic Genes 61/4500 86/10654 6.221457834340292e-8 2.0532281647137226e-7 8.205481279582816e-8 5563/7531/10971/9997/27327/7295/7533/2810/53632/7001/192669/2475/4513/4343/64121/7296/2936/51422/7249/27244/7534/1351/2821/10000/2877/54541/7157/50484/26523/2744/57521/83667/7532/1345/64223/5571/10128/25824/8626/208/55004/5562/1340/5564/5565/7248/7529/27161/27165/207/57690/192670/2539/54205/143686/5728/23112/10542/1349/1327/5052 61 Varicella.zoster_virus R-HSA-499943 Interconversion of nucleotide di- and triphosphates 27/4500 30/10654 6.384665738968868e-8 2.0971749109648328e-7 8.381109205333748e-8 4832/654364/221264/7295/1841/205/7296/6241/158067/203/2936/4831/102157402/4833/7298/50484/204/2745/1854/2987/51727/26289/1503/6240/4830/122481/79077 27 Varicella.zoster_virus R-HSA-6804758 Regulation of TP53 Activity through Acetylation 27/4500 30/10654 6.384665738968868e-8 2.0971749109648328e-7 8.381109205333748e-8 64769/84289/29117/5928/1107/5371/23774/3622/27154/57459/10000/7994/3066/7157/5608/7862/9219/5931/1108/54815/208/53615/5305/207/2033/3065/5300 27 Varicella.zoster_virus R-HSA-176033 Interactions of Vpr with host cellular proteins 31/4500 36/10654 6.488158541560216e-8 2.1261665079854603e-7 8.496970662285433e-8 23165/348995/57122/23511/292/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/3159/79023/23636/53371/9688/8480/291 31 Varicella.zoster_virus R-HSA-1592230 Mitochondrial biogenesis 66/4500 95/10654 6.61477993831542e-8 2.162583792479702e-7 8.642507992868664e-8 5563/55735/79718/53632/3313/5469/10989/1432/1387/25813/6907/2101/10499/23054/1386/9572/85441/3054/7019/814/96764/23408/51422/5465/54927/4208/6604/80205/6742/5600/6300/801/133522/64216/805/4899/5442/79135/3418/23082/23410/8834/4209/2553/5571/2551/4580/6648/211/10651/5564/51106/23373/5565/2746/8841/200186/9611/23409/54205/6256/10498/1385/808/8648/10891 66 Varicella.zoster_virus R-HSA-180910 Vpr-mediated nuclear import of PICs 29/4500 33/10654 6.739891456296247e-8 2.193214096267963e-7 8.764918345815265e-8 23165/348995/57122/23511/23279/23225/3836/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/3159/79023/23636/53371/9688/8480 29 Varicella.zoster_virus R-HSA-389356 CD28 co-stimulation 29/4500 33/10654 6.739891456296247e-8 2.193214096267963e-7 8.764918345815265e-8 5295/941/2534/2885/2475/5062/5879/5290/57761/9020/6714/10000/7525/7409/3932/253260/5170/64223/8503/4067/5063/998/208/79109/5058/9402/207/942/5296 29 Varicella.zoster_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 19/4500 19/10654 7.563892570263233e-8 2.4218334926806135e-7 9.678568474745327e-8 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Varicella.zoster_virus R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 19/4500 19/10654 7.563892570263233e-8 2.4218334926806135e-7 9.678568474745327e-8 11065/7321/8697/51529/29945/51434/29882/996/51433/119504/7324/64682/246184/8881/10393/51343/25906/991/8556 19 Varicella.zoster_virus R-HSA-176412 Phosphorylation of the APC/C 19/4500 19/10654 7.563892570263233e-8 2.4218334926806135e-7 9.678568474745327e-8 11065/7321/8697/51529/29945/51434/29882/996/983/51433/119504/7324/64682/246184/8881/891/10393/25906/5347 19 Varicella.zoster_virus R-HSA-3928664 Ephrin signaling 19/4500 19/10654 7.563892570263233e-8 2.4218334926806135e-7 9.678568474745327e-8 1947/2051/2050/2047/2534/1948/8440/8874/5062/5879/6714/1949/10627/2049/5063/6386/2048/5058/28964 19 Varicella.zoster_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 19/4500 19/10654 7.563892570263233e-8 2.4218334926806135e-7 9.678568474745327e-8 5295/4893/5335/2885/3845/3265/7314/5290/6233/6464/6654/7311/1956/2549/11140/7316/1950/867/3320 19 Varicella.zoster_virus R-HSA-77595 Processing of Intronless Pre-mRNAs 19/4500 19/10654 7.563892570263233e-8 2.4218334926806135e-7 9.678568474745327e-8 51585/81608/1477/53981/11051/8106/1478/23283/10914/10898/51692/22916/1479/79869/29894/4686/8189/10978/55339 19 Varicella.zoster_virus R-HSA-8851708 Signaling by FGFR2 IIIa TM 19/4500 19/10654 7.563892570263233e-8 2.4218334926806135e-7 9.678568474745327e-8 5431/5435/5433/5439/5438/2247/2246/2963/5434/5436/2263/2962/5432/22916/5440/5430/5441/4686/5437 19 Varicella.zoster_virus R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 22/4500 23/10654 7.767598771475182e-8 2.4757004303605833e-7 9.893841261431978e-8 5431/5435/5433/5439/51497/5438/7936/6829/25920/2963/5434/5436/2962/5432/22916/5440/5430/5441/4686/9150/5437/6827 22 Varicella.zoster_virus R-HSA-5654693 FRS-mediated FGFR1 signaling 22/4500 23/10654 7.767598771475182e-8 2.4757004303605833e-7 9.893841261431978e-8 4893/2250/2885/2253/3845/3265/8074/2260/2249/2248/2247/2246/2251/5781/6654/8822/10817/2254/26281/10818/2255/27006 22 Varicella.zoster_virus R-HSA-70171 Glycolysis 52/4500 71/10654 1.0807687690418322e-7 3.436795447795895e-7 1.3734742778855563e-7 23165/7167/5313/5211/348995/57122/3099/23511/23279/23225/9972/5518/8021/2026/55746/5515/2597/5567/10762/5528/79902/5519/9883/226/2821/6396/129401/230/4928/5903/55706/7175/5568/4927/5566/2023/8086/5516/81929/9631/5315/79023/23636/5214/53371/5230/3098/9688/5210/5209/5213/8480 52 Varicella.zoster_virus R-HSA-9609507 Protein localization 102/4500 163/10654 1.1016850745113914e-7 3.495346281858869e-7 1.3968734198350178e-7 6811/9218/26063/7321/10965/10901/5621/1384/23600/3313/10005/8239/10440/50/7917/819/3417/390916/51142/25813/4358/80273/3421/5192/7314/1891/54677/10952/26061/51608/8528/847/7323/54927/3329/100287932/2053/8604/8309/10455/2010/196743/11001/6233/6844/1610/9804/83752/373156/5264/189/3155/10531/5193/351/122970/51/55825/91452/8266/7416/1678/150274/1962/118424/4580/54363/5830/10651/51179/7311/6342/84896/5195/29928/3295/10063/51268/8310/5824/7316/10165/7322/56993/3416/5825/26521/4843/26517/92609/617/54543/5828/283927/224/1537/219743/570/3162/5194/8443/291 102 Varicella.zoster_virus R-HSA-912694 Regulation of IFNA signaling 24/4500 26/10654 1.1579963775197789e-7 3.6656756077496857e-7 1.4649435018152116e-7 3443/5777/5770/9021/11274/3445/3444/3451/3448/3439/3452/6773/7297/5781/3446/3455/6772/8651/3440/3454/3716/3456/3441/3449 24 Varicella.zoster_virus R-HSA-111465 Apoptotic cleavage of cellular proteins 32/4500 38/10654 1.1821456219645836e-7 3.725226384339862e-7 1.4887422588599965e-7 2339/660/836/9414/4001/6709/6093/840/2934/22985/63967/841/100506658/7082/5339/10134/999/5588/5580/839/1828/5747/118/1829/1832/4000/51765/1499/329/4137/7431/6304 32 Varicella.zoster_virus R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 32/4500 38/10654 1.1821456219645836e-7 3.725226384339862e-7 1.4887422588599965e-7 5908/3313/6175/3936/5898/3181/4001/4282/5062/1072/6627/9049/27250/9987/3185/3458/5478/302/552900/6775/4478/998/6648/2939/6888/3586/829/6647/6950/4507/375/5721 32 Varicella.zoster_virus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 28/4500 32/10654 1.4117618306734028e-7 4.4288079002698214e-7 1.7699202134994764e-7 892/4609/4089/22938/4088/1030/904/7314/5054/7027/6667/4092/7050/6233/1025/4221/3726/1024/60436/8812/1874/905/4087/7311/7316/1875/5933/3065 28 Varicella.zoster_virus R-HSA-5656169 Termination of translesion DNA synthesis 28/4500 32/10654 1.4117618306734028e-7 4.4288079002698214e-7 1.7699202134994764e-7 5982/6117/10714/7314/6118/9636/11201/51455/5985/5984/6233/5424/54107/7706/5425/5111/6119/5427/9246/51426/7311/5983/56655/57804/7316/5426/9100/5981 28 Varicella.zoster_virus R-HSA-2559583 Cellular Senescence 118/4500 195/10654 1.670637859078514e-7 5.229171415411672e-7 2.0897759388992507e-7 1912/3725/9134/11065/4790/7321/6045/8697/27327/80012/7295/5925/472/79813/3576/2114/1869/1911/4194/1031/5928/1432/4683/23512/57332/192669/8900/51529/4001/29945/8091/51434/1032/1030/6196/4343/6197/29882/4217/3569/7314/996/7014/5601/5606/7027/2146/5594/898/890/5970/9261/6667/51433/5598/84733/119504/6195/7157/7324/64682/6233/2353/8726/5600/26523/5608/6015/1019/9448/246184/1029/8535/5931/7013/1051/50488/8881/6774/3552/10524/5602/10393/1870/51343/7311/25906/57634/648/23466/3456/2113/6416/23523/5595/1017/25913/3159/7290/10111/57690/1027/192670/3490/8550/29855/7316/1026/1871/1021/25842/23135/23112/5609/5599/10919/4193/23043 118 Varicella.zoster_virus R-HSA-113510 E2F mediated regulation of DNA replication 21/4500 22/10654 1.7661338142757768e-7 5.491142104073461e-7 2.194469397646611e-7 5925/5422/1869/84515/4998/28227/5518/5001/5558/5515/23594/7027/5557/983/5519/23649/4999/5000/891/23595/5516 21 Varicella.zoster_virus R-HSA-442982 Ras activation upon Ca2+ influx through NMDA receptor 21/4500 22/10654 1.7661338142757768e-7 5.491142104073461e-7 2.194469397646611e-7 4893/817/1741/1739/1740/3845/3265/5923/818/2902/2906/801/4747/805/2904/816/5924/815/1742/88/808 21 Varicella.zoster_virus R-HSA-912631 Regulation of signaling by CBL 21/4500 22/10654 1.7661338142757768e-7 5.491142104073461e-7 2.194469397646611e-7 5295/5291/2534/2885/1399/7314/5290/6233/7525/7409/6850/8503/2889/4067/7311/5293/7316/3055/867/1398/5296 21 Varicella.zoster_virus R-HSA-1368082 RORA activates gene expression 18/4500 18/10654 1.7949478218946823e-7 5.519266870847966e-7 2.2057091249807136e-7 79718/5469/1387/6907/10499/23054/85441/96764/5465/6604/80205/1374/6095/6720/2033/6256/10498/8648 18 Varicella.zoster_virus R-HSA-5654221 Phospholipase C-mediated cascade; FGFR2 18/4500 18/10654 1.7949478218946823e-7 5.519266870847966e-7 2.2057091249807136e-7 2250/5335/2252/2253/8823/8074/2249/2248/2247/2246/2251/2263/8822/8817/2254/26281/2255/27006 18 Varicella.zoster_virus R-HSA-5654704 SHC-mediated cascade:FGFR3 18/4500 18/10654 1.7949478218946823e-7 5.519266870847966e-7 2.2057091249807136e-7 4893/2250/2885/2253/3845/3265/8823/8074/2249/2247/2246/6464/6654/8822/8817/2254/26281/2261 18 Varicella.zoster_virus R-HSA-5654710 PI-3K cascade:FGFR3 18/4500 18/10654 1.7949478218946823e-7 5.519266870847966e-7 2.2057091249807136e-7 5295/2250/2885/2253/5290/8823/8074/2249/2247/2246/5781/2549/8822/8817/2254/26281/10818/2261 18 Varicella.zoster_virus R-HSA-73780 RNA Polymerase III Chain Elongation 18/4500 18/10654 1.7949478218946823e-7 5.519266870847966e-7 2.2057091249807136e-7 55718/5435/84265/10622/661/11128/9533/5434/10623/51728/171568/10621/5440/5441/51082/55703/27297/5437 18 Varicella.zoster_virus R-HSA-1236394 Signaling by ERBB4 44/4500 58/10654 1.894260247053512e-7 5.811840230520226e-7 2.3226325759129244e-7 5295/4893/2670/51741/6776/4734/10413/145957/83737/6868/9542/2885/3845/3265/7314/6387/1839/5290/2065/2069/348/11059/6714/2099/5664/1447/2567/3925/6233/5663/6464/5241/3084/6654/10718/7311/1956/685/7316/1950/9611/2066/6285/1742 44 Varicella.zoster_virus R-HSA-373755 Semaphorin interactions 48/4500 65/10654 2.1946294937949205e-7 6.718646432758133e-7 2.6850268506724563e-7 5361/2909/388/2064/5788/3688/23365/79784/2534/9475/1808/8482/4628/6093/10507/5062/5879/1400/1072/7094/389/10371/3672/2932/64218/80031/9723/10154/57556/10627/4233/5063/3326/387/5058/1020/4629/3984/4627/1809/9037/10398/4637/3320/103910/8851/6237/2242 48 Varicella.zoster_virus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 23/4500 25/10654 2.5439245669640847e-7 7.73707776793434e-7 3.0920307774130606e-7 2308/2475/7249/2932/10000/2931/253260/5170/572/4303/6199/64223/208/79109/1147/2309/842/207/1027/1026/3164/1385/4193 23 Varicella.zoster_virus R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 23/4500 25/10654 2.5439245669640847e-7 7.73707776793434e-7 3.0920307774130606e-7 5520/8900/28227/5518/7465/5515/993/890/983/5519/7514/2305/9133/891/4331/5347/5516/1017/994/902/9088/995/1022 23 Varicella.zoster_virus R-HSA-9620244 Long-term potentiation 23/4500 25/10654 2.5439245669640847e-7 7.73707776793434e-7 3.0920307774130606e-7 817/1741/1739/1740/818/2902/6714/2906/801/2891/4747/805/2904/2890/2905/3084/816/815/2903/2066/1742/88/808 23 Varicella.zoster_virus R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 42/4500 55/10654 2.622690160732202e-7 7.95929448778729e-7 3.1808370370436315e-7 51807/347688/10381/1780/3305/8655/832/7846/3306/3312/51164/3303/3337/3301/10540/140735/84617/5241/11258/1783/10382/10294/830/7277/10671/1639/2908/51143/3326/367/10383/84790/3304/7280/10728/829/1778/1781/10121/3320/10963/2288 42 Varicella.zoster_virus R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 27/4500 31/10654 2.944747249400897e-7 8.897980866155091e-7 3.5559718436602314e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/79023/23636/53371/9688/8480 27 Varicella.zoster_virus R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 27/4500 31/10654 2.944747249400897e-7 8.897980866155091e-7 3.5559718436602314e-7 23165/348995/57122/23511/23279/23225/9972/8021/55746/10762/79902/9883/6396/129401/4928/5903/55706/7175/4927/8086/81929/9631/79023/23636/53371/9688/8480 27 Varicella.zoster_virus R-HSA-877300 Interferon gamma signaling 63/4500 92/10654 3.0120449940323304e-7 9.081673459328581e-7 3.6293823959011834e-7 80263/5777/960/5770/3107/817/9021/3383/3662/3115/4684/567/6672/3106/3459/3717/5371/3133/3127/4938/4261/818/115362/7412/9830/2634/10612/3458/3661/5580/81603/4940/5781/3660/8554/3135/3665/10379/2633/3123/2209/8638/7706/3122/3394/3663/6772/8651/3659/5771/816/10346/3716/3105/3460/815/6737/4281/3664/4939/7341/3134/5724 63 Varicella.zoster_virus R-HSA-437239 Recycling pathway of L1 37/4500 47/10654 3.526661794483057e-7 1.0610387640298163e-6 4.2403147710436037e-7 9252/71/7430/51807/347688/1785/10381/285643/7846/1808/6456/163/6196/1759/6197/161/5594/8650/6714/6195/1213/1211/1175/1173/84617/10382/7277/4478/160/26052/27330/3897/10383/24137/60/84790/7280 37 Varicella.zoster_virus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 32/4500 39/10654 3.9095827829432145e-7 1.1737156053739198e-6 4.6906143179624315e-7 5982/25898/6117/10714/55666/7314/6118/9636/11201/51455/5985/5984/6233/5424/54107/7706/5425/5111/6119/5427/9246/51426/7311/5983/56655/57804/7316/5426/9100/7415/5981/5980 32 Varicella.zoster_virus R-HSA-4551638 SUMOylation of chromatin organization proteins 51/4500 71/10654 3.9718907369399754e-7 1.189862546945967e-6 4.755143642598119e-7 1912/23165/6045/80012/348995/6613/57122/23511/9759/1911/23279/23225/23512/57332/1107/9972/6612/8021/55746/10762/79902/9883/84733/3066/9063/6396/129401/9189/6015/8554/4928/5903/55706/7175/8535/4927/8086/7329/648/23468/81929/9631/79023/23636/53371/9688/7341/3065/23314/6304/8480 51 Varicella.zoster_virus R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 20/4500 21/10654 4.00740306844075e-7 1.1902839752219758e-6 4.7568278303999946e-7 2237/5982/6117/10714/6118/328/3978/5985/5984/5424/54107/5425/5111/6119/5427/5983/56655/57804/5426/5981 20 Varicella.zoster_virus R-HSA-5654688 SHC-mediated cascade:FGFR1 20/4500 21/10654 4.00740306844075e-7 1.1902839752219758e-6 4.7568278303999946e-7 4893/2250/2885/2253/3845/3265/8074/2260/2249/2248/2247/2246/2251/6464/6654/8822/2254/26281/2255/27006 20 Varicella.zoster_virus R-HSA-5654689 PI-3K cascade:FGFR1 20/4500 21/10654 4.00740306844075e-7 1.1902839752219758e-6 4.7568278303999946e-7 5295/2250/2885/2253/5290/8074/2260/2249/2248/2247/2246/2251/5781/2549/8822/2254/26281/10818/2255/27006 20 Varicella.zoster_virus R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 20/4500 21/10654 4.00740306844075e-7 1.1902839752219758e-6 4.7568278303999946e-7 25904/55571/55835/57472/85456/29883/1263/7832/10769/7157/5325/4869/4850/246175/4848/23019/4849/9337/28984/995 20 Varicella.zoster_virus R-HSA-180292 GAB1 signalosome 17/4500 17/10654 4.258947129487777e-7 1.2543228254778347e-6 5.012751451540134e-7 5295/374/7039/55824/2885/5829/1839/5290/2069/6714/1445/255324/5781/1956/2549/685/1950 17 Varicella.zoster_virus R-HSA-2033519 Activated point mutants of FGFR2 17/4500 17/10654 4.258947129487777e-7 1.2543228254778347e-6 5.012751451540134e-7 2250/2252/2253/8823/8074/2249/2248/2247/2246/2251/2263/8822/8817/2254/26281/2255/27006 17 Varicella.zoster_virus R-HSA-432142 Platelet sensitization by LDL 17/4500 17/10654 4.258947129487777e-7 1.2543228254778347e-6 5.012751451540134e-7 5777/5526/5175/2268/1432/5518/5515/5528/5519/5781/338/5529/5516/5321/5525/5527/7804 17 Varicella.zoster_virus R-HSA-8934593 Regulation of RUNX1 Expression and Activity 17/4500 17/10654 4.258947129487777e-7 1.2543228254778347e-6 5.012751451540134e-7 27327/192669/5371/4343/865/6714/595/896/26523/5781/27161/894/57690/192670/1021/861/23112 17 Varicella.zoster_virus R-HSA-9006936 Signaling by TGF-beta family members 68/4500 102/10654 4.9904003220048e-7 1.4666523893723579e-6 5.861301209224474e-7 892/7321/4738/130399/8239/9612/4609/4089/22938/23327/4088/5499/1030/7040/10589/904/7314/5054/7027/6497/51592/50848/7323/6667/4092/11171/7050/94/5494/9958/9040/6233/7514/1025/57530/5500/4090/4221/4093/5590/9765/269/3726/5501/1024/60436/8812/1874/142/905/4087/7048/7311/387/57154/9241/51377/10273/4086/64750/659/7316/1875/9611/5933/867/3065/56288 68 Varicella.zoster_virus R-HSA-76002 Platelet activation, signaling and aggregation 150/4500 262/10654 5.267589977010494e-7 1.5448646235098e-6 6.173867067261305e-7 5295/5777/5579/5770/5291/7042/2770/5175/5578/5908/3082/388/5583/7423/1432/3920/374354/2244/3309/2534/3690/408/2768/2782/87/2776/5894/10487/2885/7040/9564/5874/54863/350/7043/2773/5879/5054/2787/5099/1072/5290/7018/5336/813/7094/5594/7414/10490/7534/6810/10125/6714/7273/22927/1191/146850/27154/226/5588/2335/5294/2783/2784/1445/8525/5478/2771/94121/7410/5580/2266/7409/5154/3932/7076/2243/801/5781/805/5170/5590/351/6464/135228/5747/3937/7424/2316/3674/409/7277/10451/334/1277/10447/335/51706/308/6850/8503/197/4067/81/9948/998/3481/54495/6654/8407/7450/387/29789/10916/5595/7066/5321/59345/1606/207/26090/7422/54518/1950/55970/5216/2767/6647/4352/27040/1893/7078/2/1398/948/88/10235/5906/3479/5155/5296/5581/51368/808/213/7057/1278/9002/2207/6814 150 Varicella.zoster_virus R-HSA-2871809 FCERI mediated Ca+2 mobilization 28/4500 33/10654 5.543288866918542e-7 1.6223126327501643e-6 6.483378791717593e-7 5335/5530/2885/4773/5336/7410/7409/3702/801/805/6464/2205/4772/3937/4775/10451/2206/6850/4067/695/6654/9402/5532/10768/27040/5534/808/2207 28 Varicella.zoster_virus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 22/4500 24/10654 5.570398052349345e-7 1.6268359165438675e-6 6.501455555483711e-7 374/7039/1839/5594/2069/10000/595/7514/2353/255324/5747/208/1956/5595/596/685/2309/207/1027/1950/2002/1385 22 Varicella.zoster_virus R-HSA-5696394 DNA Damage Recognition in GG-NER 31/4500 38/10654 7.661105769861108e-7 2.228104928067939e-6 8.904355390408745e-7 10445/9978/10980/10987/7314/83444/86/1643/10920/6233/93973/8607/5886/8451/8450/1642/142/125476/1069/2873/7311/60/51138/7528/9318/7316/64708/283899/54617/5887/7508 31 Varicella.zoster_virus R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 31/4500 38/10654 7.661105769861108e-7 2.228104928067939e-6 8.904355390408745e-7 1912/1459/6045/80012/1460/28996/1457/1911/6603/10138/57332/57492/86/865/84733/6604/8289/6602/23429/6015/6595/6597/8535/6599/648/6601/23466/6598/2033/6605/861 31 Varicella.zoster_virus R-HSA-6807878 COPI-mediated anterograde transport 67/4500 101/10654 7.981283926105653e-7 2.316397580216942e-6 9.257206435793843e-7 6811/6711/51807/347688/5861/10381/1780/9570/8655/832/7846/9382/3630/6709/10652/54732/51164/2801/10466/1315/8615/11316/91949/8729/1314/10540/51332/378/140735/10959/22820/84617/11258/6712/1783/10382/830/7277/10671/966/1639/6710/8775/81876/51143/10383/84790/7280/829/1778/11070/25839/1781/57731/10121/2804/9527/57511/10972/381/6708/4905/9276/287/375/64689/22818 67 Varicella.zoster_virus R-HSA-167044 Signalling to RAS 19/4500 20/10654 9.072474848663347e-7 2.611376265718357e-6 1.043605354268383e-6 4893/5898/1432/5603/2885/3845/3265/5899/9261/6714/4914/5600/6300/6464/6654/5900/25759/53358/4803 19 Varicella.zoster_virus R-HSA-3232118 SUMOylation of transcription factors 19/4500 20/10654 9.072474848663347e-7 2.611376265718357e-6 1.043605354268383e-6 9112/6613/7022/6612/4286/6670/51588/7157/7158/9063/8554/7020/1029/7329/7021/3090/7341/10401/4193 19 Varicella.zoster_virus R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 19/4500 20/10654 9.072474848663347e-7 2.611376265718357e-6 1.043605354268383e-6 472/1387/51499/7159/637/27166/23368/7157/63970/55240/5366/84883/147923/94241/8626/7161/665/27113/581 19 Varicella.zoster_virus R-HSA-8876384 Listeria monocytogenes entry into host cells 19/4500 20/10654 9.072474848663347e-7 2.611376265718357e-6 1.043605354268383e-6 6456/30011/2885/7314/8027/2060/1500/6714/999/9146/6455/6233/4233/7311/1499/7316/867/10254/6457 19 Varicella.zoster_virus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 172/4500 309/10654 9.91370185082496e-7 2.847639461677293e-6 1.1380251204109226e-6 8454/5689/11065/55070/5682/7321/9021/8697/9817/7174/6478/143471/5705/57674/9690/8452/5709/9978/5695/4734/7337/7704/3093/5711/23327/51465/10616/5683/89910/25898/5699/7328/7428/5702/22954/83737/51529/10075/29945/8924/56658/51434/10425/25793/29882/7334/92591/84961/7332/5696/5691/9820/55658/7314/996/5718/8945/64410/5700/122706/5707/23198/10533/6477/7323/4008/11059/51433/9861/6502/5698/27246/5692/5713/79654/5710/9040/7324/5719/64682/8925/51191/6233/6047/868/5930/11275/29116/23608/55585/51132/899/23352/246184/151636/10193/81559/5706/26263/8881/7317/80196/84078/5714/26272/8651/5688/5687/26270/63893/118424/5708/55008/63891/9246/10393/5704/9520/4012/7327/51343/7311/9320/57520/5694/997/7325/140691/57154/5684/6737/8065/5720/7319/54850/26046/991/10273/7320/5690/5717/9491/6500/26259/10197/7336/64750/23376/7316/10213/114907/54926/25831/7322/5715/5701/23291/5685/5686/55521/55294/8453/80176/8139/5716/7064/80204/27338/23014/90678/5693/5721 172 Varicella.zoster_virus R-HSA-156711 Polo-like kinase mediated events 16/4500 16/10654 1.0104076619868665e-6 2.8786308084360524e-6 1.1504104422192037e-6 5928/7465/993/2305/9133/286826/891/91750/55957/5347/4605/1063/9088/2033/995/132660 16 Varicella.zoster_virus R-HSA-1963640 GRB2 events in ERBB2 signaling 16/4500 16/10654 1.0104076619868665e-6 2.8786308084360524e-6 1.1504104422192037e-6 4893/2064/145957/9542/2885/3845/3265/1839/2069/3084/6654/10718/1956/685/1950/2066 16 Varicella.zoster_virus R-HSA-1963642 PI3K events in ERBB2 signaling 16/4500 16/10654 1.0104076619868665e-6 2.8786308084360524e-6 1.1504104422192037e-6 5295/2064/145957/9542/2885/1839/5290/2065/2069/3084/10718/1956/2549/685/1950/2066 16 Varicella.zoster_virus R-HSA-9614657 FOXO-mediated transcription of cell death genes 16/4500 16/10654 1.0104076619868665e-6 2.8786308084360524e-6 1.1504104422192037e-6 2308/65018/356/1387/4801/604/4303/4800/10370/6794/27113/2309/10018/4802/1649/2033 16 Varicella.zoster_virus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 21/4500 23/10654 1.2154560154122455e-6 3.441737520315405e-6 1.375449318177624e-6 7321/8239/9612/4089/23327/4088/7314/6497/51592/7323/7050/5494/6233/60436/142/4087/7311/64750/7316/9611/3065 21 Varicella.zoster_virus R-HSA-73980 RNA Polymerase III Transcription Termination 21/4500 23/10654 1.2154560154122455e-6 3.441737520315405e-6 1.375449318177624e-6 55718/4774/5435/84265/10622/661/11128/9533/5434/10623/51728/171568/10621/4784/5440/5441/51082/55703/27297/5437/6741 21 Varicella.zoster_virus R-HSA-9617324 Negative regulation of NMDA receptor-mediated neuronal transmission 21/4500 23/10654 1.2154560154122455e-6 3.441737520315405e-6 1.375449318177624e-6 817/1741/1739/1740/814/818/2902/2906/801/4747/805/2904/2905/816/815/2903/9647/1742/88/808/8536 21 Varicella.zoster_virus R-HSA-157118 Signaling by NOTCH 135/4500 235/10654 1.4993934184283685e-6 4.237152251267211e-6 1.6933273210463145e-006 8454/5689/3725/79718/5682/892/4904/182/27327/3091/5705/5709/9978/1869/5695/9759/9612/4609/22938/5711/1387/4088/6907/5683/408/5699/6400/4853/5702/192669/83737/6868/9794/4343/9787/388585/5696/5691/7314/5718/23286/79885/2648/9734/7027/5700/5707/51564/55534/3280/84441/10013/7534/4854/7091/8650/102/5664/10320/9861/5870/8850/5087/5698/5692/5713/595/5710/3066/7157/5719/6233/2324/26523/5663/10959/1999/409/5706/10460/10046/1024/5714/6772/10014/489/5688/5687/5708/59/4855/5704/23493/7311/1956/5694/4851/27161/5684/8841/2208/5720/5584/23462/207/5690/57690/5717/9491/6500/51548/10197/192670/488/7316/10213/1950/9611/1871/5715/5701/5685/5686/2033/55294/3065/861/2683/23112/5716/1385/54567/3516/5693/5721 135 Varicella.zoster_virus R-HSA-1980143 Signaling by NOTCH1 51/4500 73/10654 1.5760606986900532e-6 4.444809566406696e-6 1.776315088369438e-6 8454/79718/892/182/3091/9978/9759/9612/4609/22938/1387/6907/408/83737/6868/9794/388585/7314/79885/2648/9734/51564/55534/3280/84441/10013/7091/8650/102/5664/8850/3066/6233/5663/409/10046/1024/10014/23493/7311/4851/8841/23462/6500/7316/9611/2033/55294/3065/54567/3516 51 Varicella.zoster_virus R-HSA-5619115 Disorders of transmembrane transporters 105/4500 176/10654 2.047592811754102e-6 5.743503368951219e-6 2.2953225648802192e-6 5244/23165/5689/6507/5682/285195/348995/143471/57122/5705/23511/5709/5695/554/6523/23279/5711/23225/5683/5699/6400/5702/4891/1836/9972/8021/55746/5696/5691/6513/7314/5718/5700/122706/5707/10956/79139/91445/23198/10762/9861/79902/9883/5698/5692/5713/5710/5719/6233/6575/6396/129401/4928/5903/55706/7175/7355/5706/9843/19/335/5714/4927/5688/5687/5708/8086/6514/5704/7311/11160/5694/9197/81929/5684/5720/9631/5690/5717/9491/1080/79023/23636/10197/1244/7316/10213/53371/3098/9688/7415/6519/5715/5701/5685/682/5686/6520/5716/213/5693/551/5721/6566/8480 105 Varicella.zoster_virus R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 18/4500 19/10654 2.0489001989525123e-6 5.743503368951219e-6 2.2953225648802192e-6 1869/4609/5928/990/7027/7153/5934/993/286826/5111/91750/1874/55957/4149/1875/5933/3065/132660 18 Varicella.zoster_virus R-HSA-6804760 Regulation of TP53 Activity through Methylation 18/4500 19/10654 2.0489001989525123e-6 5.743503368951219e-6 2.2953225648802192e-6 133383/11200/472/79813/4194/56950/7314/7157/6233/10419/26013/7311/7316/2033/91875/133746/10919/4193 18 Varicella.zoster_virus R-HSA-382556 ABC-family proteins mediated transport 67/4500 103/10654 2.3113656497668242e-6 6.466265424998971e-6 2.5841657934319526e-6 5244/5689/1965/5682/143471/5705/5709/5695/5711/5683/5699/6400/5702/4363/10057/5696/5691/7314/5718/5700/122706/5707/10956/79139/91445/23198/9861/8894/5698/5692/5713/5710/5719/6233/1968/5243/5706/335/340273/5714/5688/5687/5708/5704/7311/11160/5694/5684/5720/5690/5717/9491/1080/10197/5824/1244/7316/10213/7415/5715/5701/5825/5685/5686/5716/5693/5721 67 Varicella.zoster_virus R-HSA-111447 Activation of BAD and translocation to mitochondria 15/4500 15/10654 2.396817640106634e-6 6.5735902270901e-6 2.627056869520249e-6 7531/10971/7533/2810/637/7534/10000/572/7532/208/7529/5533/596/207/5534 15 Varicella.zoster_virus R-HSA-1170546 Prolactin receptor signaling 15/4500 15/10654 2.396817640106634e-6 6.5735902270901e-6 2.627056869520249e-6 8454/6776/9978/3717/5618/8945/2690/5617/6777/5781/1442/2689/6500/25970/2688 15 Varicella.zoster_virus R-HSA-354194 GRB2:SOS provides linkage to MAPK signaling for Integrins 15/4500 15/10654 2.396817640106634e-6 6.5735902270901e-6 2.627056869520249e-6 5908/2244/3690/2885/7094/6714/2335/2266/2243/5747/3674/6654/7450/54518/5906 15 Varicella.zoster_virus R-HSA-372708 p130Cas linkage to MAPK signaling for integrins 15/4500 15/10654 2.396817640106634e-6 6.5735902270901e-6 2.627056869520249e-6 5908/2244/3690/9564/7094/6714/2335/2266/2243/5747/3674/7450/54518/1398/5906 15 Varicella.zoster_virus R-HSA-5637810 Constitutive Signaling by EGFRvIII 15/4500 15/10654 2.396817640106634e-6 6.5735902270901e-6 2.627056869520249e-6 5295/4893/5335/2885/3845/3265/5290/6464/6654/1956/2549/11140/1950/867/3320 15 Varicella.zoster_virus R-HSA-5637812 Signaling by EGFRvIII in Cancer 15/4500 15/10654 2.396817640106634e-6 6.5735902270901e-6 2.627056869520249e-6 5295/4893/5335/2885/3845/3265/5290/6464/6654/1956/2549/11140/1950/867/3320 15 Varicella.zoster_virus R-HSA-5654228 Phospholipase C-mediated cascade; FGFR4 15/4500 15/10654 2.396817640106634e-6 6.5735902270901e-6 2.627056869520249e-6 5335/9965/2264/2253/8823/8074/2249/2247/2246/2251/8822/8817/2254/152831/26281 15 Varicella.zoster_virus R-HSA-6785631 ERBB2 Regulates Cell Motility 15/4500 15/10654 2.396817640106634e-6 6.5735902270901e-6 2.627056869520249e-6 2064/145957/9542/1839/2065/2069/1729/3084/10718/387/1956/685/1950/51072/2066 15 Varicella.zoster_virus R-HSA-69183 Processive synthesis on the lagging strand 15/4500 15/10654 2.396817640106634e-6 6.5735902270901e-6 2.627056869520249e-6 2237/1763/5422/6117/10714/5558/6118/3978/5557/23649/5424/5425/5111/6119/57804 15 Varicella.zoster_virus R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 15/4500 15/10654 2.396817640106634e-6 6.5735902270901e-6 2.627056869520249e-6 6456/30011/2885/7314/8027/2060/9146/6455/6233/4233/7311/7316/867/10254/6457 15 Varicella.zoster_virus R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 24/4500 28/10654 2.598594122798515e-6 7.1130145008367195e-6 2.842631341761018e-6 10381/10576/7846/7411/10574/10693/5201/5204/10575/10471/5202/84617/10382/7277/10383/60/84790/22948/7280/10694/5203/7203/908/6950 24 Varicella.zoster_virus R-HSA-199992 trans-Golgi Network Vesicle Budding 50/4500 72/10654 2.6397368666882905e-6 7.211492496862727e-6 2.881986897404046e-6 27131/8773/8906/162/1176/5286/1212/1174/1785/8546/11154/7037/3482/408/6456/3312/1362/25977/10618/6643/10053/6810/8301/9146/8729/4074/2495/6844/1213/2580/1211/8907/351/84062/9685/9026/8775/9829/8905/51429/8673/164/1777/6272/2804/9698/5878/6845/375/4952 50 Varicella.zoster_virus R-HSA-8854691 Interleukin-20 family signaling 22/4500 25/10654 2.776453694517487e-6 7.570174526457836e-6 3.0253298891740716e-6 11009/6776/3717/282618/50604/3588/55801/3718/6777/6773/7297/5781/6775/50616/53833/6774/6772/29949/163702/3716/58985/53832 22 Varicella.zoster_virus R-HSA-70326 Glucose metabolism 60/4500 91/10654 4.025876379509044e-6 1.0955406288098685e-5 4.37819735537046e-6 23165/7167/5313/2806/5211/348995/57122/3099/23511/23279/23225/9972/5518/4191/8021/2026/55746/5515/2597/5567/10762/5528/79902/5519/9883/226/2821/8604/6396/129401/230/5105/4928/5903/55706/7175/5568/2805/4927/5566/2023/4190/8086/5516/81929/9631/5091/5315/79023/23636/5214/53371/5230/10165/3098/9688/5210/5209/5213/8480 60 Varicella.zoster_virus R-HSA-5693532 DNA Double-Strand Break Repair 99/4500 166/10654 4.063478796834145e-6 1.103621867778301e-5 4.410493062302062e-6 2237/83990/151987/9156/1763/7486/27343/5982/11200/472/6613/27434/64421/4683/165918/84126/8900/8924/2067/672/6117/7334/10714/348654/83695/55183/7314/6118/25/5888/322/51588/51720/63967/5531/116028/890/9656/5985/7157/5984/6233/7158/6047/5884/5810/5424/8467/80010/3838/7515/54107/580/11073/5591/5425/641/5111/6119/3364/22976/10524/5427/144715/142/1111/7329/79728/51426/7311/3980/5536/5983/2547/79840/56655/1017/5883/10111/57804/7520/675/51548/545/7336/2072/29086/7316/8314/5426/10635/7341/5932/9025/79184/7156/5599/5981/2139 99 Varicella.zoster_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 25/4500 30/10654 4.525217300728868e-6 1.2266414275373786e-5 4.902126048822279e-6 7124/7375/10616/1540/3551/7314/8737/55072/8517/7128/10454/6233/331/8717/330/27005/7311/1147/7186/56957/6885/7316/7132/329/9099 25 Varicella.zoster_virus R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 17/4500 18/10654 4.614693535857029e-6 1.2412547545388078e-5 4.960526465884242e-6 5295/11052/613/6776/11064/2885/9846/7750/8805/26127/5290/399687/6777/1523/9208/6774/6772 17 Varicella.zoster_virus R-HSA-210993 Tie2 Signaling 17/4500 18/10654 4.614693535857029e-6 1.2412547545388078e-5 4.960526465884242e-6 5295/4893/5291/2885/3845/3265/5290/5781/6464/7010/2888/2886/6654/285/5296/284/9046 17 Varicella.zoster_virus R-HSA-5675482 Regulation of necroptotic cell death 17/4500 18/10654 4.614693535857029e-6 1.2412547545388078e-5 4.960526465884242e-6 356/7314/8737/841/8797/6233/8772/331/8717/330/8837/7311/8795/7186/355/7316/329 17 Varicella.zoster_virus R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 17/4500 18/10654 4.614693535857029e-6 1.2412547545388078e-5 4.960526465884242e-6 2810/6790/1647/7027/5934/983/7157/891/5111/1874/25946/5933/2033/995/10498/581/3276 17 Varicella.zoster_virus R-HSA-164952 The role of Nef in HIV-1 replication and disease pathogenesis 23/4500 27/10654 5.314127910794671e-6 1.4266389545133386e-5 5.701392292957846e-6 162/1174/567/2534/163/55690/5062/5879/51606/161/10053/926/3932/1175/8907/1173/160/920/8905/164/919/3055/375 23 Varicella.zoster_virus R-HSA-114604 GPVI-mediated activation cascade 28/4500 35/10654 5.569049607883863e-6 1.472359979067654e-5 5.8841109101633e-6 5295/5777/5291/388/2534/5879/5290/5336/146850/5294/7410/7409/3932/5781/5170/5590/3937/10451/1277/6850/8503/4067/998/387/27040/5296/1278/2207 28 Varicella.zoster_virus R-HSA-8953750 Transcriptional Regulation by E2F6 28/4500 35/10654 5.569049607883863e-6 1.472359979067654e-5 5.8841109101633e-6 6045/80012/79813/1869/1911/5928/10138/23512/672/6241/5888/7027/2146/1876/8726/8409/317/23429/6015/5931/1111/648/23468/23269/8317/4149/5932/10919 28 Varicella.zoster_virus R-HSA-1250347 SHC1 events in ERBB4 signaling 14/4500 14/10654 5.684828285941731e-6 1.472359979067654e-5 5.8841109101633e-6 4893/145957/9542/2885/3845/3265/1839/2069/6464/3084/6654/10718/685/2066 14 Varicella.zoster_virus R-HSA-169893 Prolonged ERK activation events 14/4500 14/10654 5.684828285941731e-6 1.472359979067654e-5 5.8841109101633e-6 5605/1399/5594/4914/673/2889/7529/5595/5604/57498/10818/4803/1398/5906 14 Varicella.zoster_virus R-HSA-174411 Polymerase switching on the C-strand of the telomere 14/4500 14/10654 5.684828285941731e-6 1.472359979067654e-5 5.8841109101633e-6 5982/5422/10714/5558/5557/5985/5984/23649/5424/5425/5111/5983/57804/5981 14 Varicella.zoster_virus R-HSA-180336 SHC1 events in EGFR signaling 14/4500 14/10654 5.684828285941731e-6 1.472359979067654e-5 5.8841109101633e-6 374/4893/7039/2885/3845/3265/1839/2069/255324/6464/6654/1956/685/1950 14 Varicella.zoster_virus R-HSA-190322 FGFR4 ligand binding and activation 14/4500 14/10654 5.684828285941731e-6 1.472359979067654e-5 5.8841109101633e-6 9965/2264/2253/8823/8074/2249/2247/2246/2251/8822/8817/2254/152831/26281 14 Varicella.zoster_virus R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 14/4500 14/10654 5.684828285941731e-6 1.472359979067654e-5 5.8841109101633e-6 4436/9156/6117/10714/6118/3978/5424/2956/4292/5425/5111/6119/57804/5395 14 Varicella.zoster_virus R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 14/4500 14/10654 5.684828285941731e-6 1.472359979067654e-5 5.8841109101633e-6 9134/57060/1869/8900/144455/898/890/7157/79733/1820/1017/25946/1027/1026 14 Varicella.zoster_virus R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 14/4500 14/10654 5.684828285941731e-6 1.472359979067654e-5 5.8841109101633e-6 7159/51230/23368/5458/10000/7157/5457/54971/8626/208/7161/25946/207/10848 14 Varicella.zoster_virus R-HSA-69091 Polymerase switching 14/4500 14/10654 5.684828285941731e-6 1.472359979067654e-5 5.8841109101633e-6 5982/5422/10714/5558/5557/5985/5984/23649/5424/5425/5111/5983/57804/5981 14 Varicella.zoster_virus R-HSA-69109 Leading Strand Synthesis 14/4500 14/10654 5.684828285941731e-6 1.472359979067654e-5 5.8841109101633e-6 5982/5422/10714/5558/5557/5985/5984/23649/5424/5425/5111/5983/57804/5981 14 Varicella.zoster_virus R-HSA-69166 Removal of the Flap Intermediate 14/4500 14/10654 5.684828285941731e-6 1.472359979067654e-5 5.8841109101633e-6 2237/1763/5422/6117/10714/5558/6118/5557/23649/5424/5425/5111/6119/57804 14 Varicella.zoster_virus R-HSA-877312 Regulation of IFNG signaling 14/4500 14/10654 5.684828285941731e-6 1.472359979067654e-5 5.8841109101633e-6 5777/5770/9021/3459/3717/3458/5781/8554/6772/8651/5771/3716/3460/7341 14 Varicella.zoster_virus R-HSA-8941856 RUNX3 regulates NOTCH signaling 14/4500 14/10654 5.684828285941731e-6 1.472359979067654e-5 5.8841109101633e-6 182/22938/1387/9794/2648/55534/3280/84441/8850/864/10046/4851/2033/3516 14 Varicella.zoster_virus R-HSA-8983432 Interleukin-15 signaling 14/4500 14/10654 5.684828285941731e-6 1.472359979067654e-5 5.8841109101633e-6 6776/2885/9846/3600/3718/6777/6464/6774/6654/3716/6655/3561/3560/3601 14 Varicella.zoster_virus R-HSA-9005891 Loss of function of MECP2 in Rett syndrome 14/4500 14/10654 5.684828285941731e-6 1.472359979067654e-5 5.8841109101633e-6 79718/9612/6907/4204/814/801/805/5566/25942/8841/9611/2874/3065/808 14 Varicella.zoster_virus R-HSA-9005895 Pervasive developmental disorders 14/4500 14/10654 5.684828285941731e-6 1.472359979067654e-5 5.8841109101633e-6 79718/9612/6907/4204/814/801/805/5566/25942/8841/9611/2874/3065/808 14 Varicella.zoster_virus R-HSA-9027284 Erythropoietin activates RAS 14/4500 14/10654 5.684828285941731e-6 1.472359979067654e-5 5.8841109101633e-6 4893/3717/2885/2056/8660/3845/3265/1399/2057/7409/6464/2889/4067/6654 14 Varicella.zoster_virus R-HSA-445144 Signal transduction by L1 19/4500 21/10654 5.719065676077796e-6 1.4757515127180411e-5 5.897664769571422e-6 1459/1460/4684/3688/1457/5605/3690/5879/5594/2260/7410/3685/3674/3678/3897/1956/5058/5595/5604 19 Varicella.zoster_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 19/4500 21/10654 5.719065676077796e-6 1.4757515127180411e-5 5.897664769571422e-6 9252/4893/4790/1387/2534/5894/3845/3265/5062/5567/5970/5568/5566/4067/5063/30835/5971/5058/2033 19 Varicella.zoster_virus R-HSA-203927 MicroRNA (miRNA) biogenesis 21/4500 24/10654 5.8243694866534225e-6 1.497388545739996e-5 5.984134589369612e-6 5431/5435/5433/5439/192669/29102/5438/54487/57510/26523/23405/5434/5436/5901/5432/27161/5440/5430/5441/192670/5437 21 Varicella.zoster_virus R-HSA-3371571 HSF1-dependent transactivation 21/4500 24/10654 5.8243694866534225e-6 1.497388545739996e-5 5.984134589369612e-6 817/3305/1387/2475/3306/3312/818/3303/3337/3297/57521/1410/64223/816/3326/3304/10728/815/3320/2033/2288 21 Varicella.zoster_virus R-HSA-75153 Apoptotic execution phase 38/4500 52/10654 6.217586095532122e-6 1.595542314221111e-5 6.376394409117695e-6 2339/10059/660/836/9414/4001/3836/6709/6093/840/5062/2934/22985/63967/841/100506658/7082/5339/10134/999/5588/5580/839/1828/5747/118/1829/1832/3148/4000/3837/51765/1499/3146/329/4137/7431/6304 38 Varicella.zoster_virus R-HSA-9024446 NR1H2 and NR1H3-mediated signaling 35/4500 47/10654 7.1673781316537084e-6 1.835900893906161e-5 7.336958782764783e-6 79718/27327/9612/55818/6907/192669/4343/1071/10062/344/348/6257/26523/29116/5105/6319/19/5346/27161/8841/347/8204/57690/6720/192670/9611/2874/2194/2033/221656/23028/6256/23112/7376/8648 35 Varicella.zoster_virus R-HSA-432722 Golgi Associated Vesicle Biogenesis 40/4500 56/10654 8.961794835070748e-6 2.2913306940950117e-5 9.157029617481198e-6 27131/162/1176/5286/1174/1785/8546/7037/3482/408/6456/3312/1362/25977/10618/6643/10053/8301/2495/6844/1213/2580/1211/8907/84062/9685/9026/8775/9829/8905/51429/8673/164/6272/2804/9698/5878/6845/375/4952 40 Varicella.zoster_virus R-HSA-5655862 Translesion synthesis by POLK 16/4500 17/10654 1.0362614846596256e-5 2.639819402527075e-5 1.0549723143864803e-5 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/51426/7311/5983/7316/5981/5980 16 Varicella.zoster_virus R-HSA-5656121 Translesion synthesis by POLI 16/4500 17/10654 1.0362614846596256e-5 2.639819402527075e-5 1.0549723143864803e-5 5982/6117/7314/6118/11201/51455/5985/5984/6233/5111/6119/7311/5983/7316/5981/5980 16 Varicella.zoster_virus R-HSA-180024 DARPP-32 events 22/4500 26/10654 1.0803793303709866e-5 2.74719407139872e-5 1.0978833191383817e-5 5530/5499/5518/5515/5567/5573/5528/5519/801/805/5568/5566/5577/1020/5516/5533/5575/5532/5576/5534/5144/808 22 Varicella.zoster_virus R-HSA-112409 RAF-independent MAPK1/3 activation 20/4500 23/10654 1.2152366531654396e-5 3.0788935895080825e-5 1.2304430722660868e-5 1844/1850/1848/1852/5605/3717/1847/3569/3572/1849/5594/983/1843/3570/7297/5781/1846/3716/5595/5604 20 Varicella.zoster_virus R-HSA-438066 Unblocking of NMDA receptors, glutamate binding and activation 20/4500 23/10654 1.2152366531654396e-5 3.0788935895080825e-5 1.2304430722660868e-5 817/1741/1739/1740/818/2902/2906/801/2891/4747/805/2904/2890/2905/816/815/2903/1742/88/808 20 Varicella.zoster_virus R-HSA-164938 Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 18/4500 20/10654 1.2323774625728174e-5 3.094242693797937e-5 1.2365771585830997e-5 162/1174/567/163/55690/51606/161/10053/926/3932/1175/8907/1173/160/920/8905/164/375 18 Varicella.zoster_virus R-HSA-5213460 RIPK1-mediated regulated necrosis 18/4500 20/10654 1.2323774625728174e-5 3.094242693797937e-5 1.2365771585830997e-5 356/7314/8737/841/8797/6233/8772/331/8717/330/8837/197259/7311/8795/7186/355/7316/329 18 Varicella.zoster_virus R-HSA-5218859 Regulated Necrosis 18/4500 20/10654 1.2323774625728174e-5 3.094242693797937e-5 1.2365771585830997e-5 356/7314/8737/841/8797/6233/8772/331/8717/330/8837/197259/7311/8795/7186/355/7316/329 18 Varicella.zoster_virus R-HSA-5625900 RHO GTPases activate CIT 18/4500 20/10654 1.2323774625728174e-5 3.094242693797937e-5 1.2365771585830997e-5 388/79784/4628/5879/4659/389/9055/5500/10627/387/4629/4627/1027/10398/4637/1742/9928/103910 18 Varicella.zoster_virus R-HSA-5627117 RHO GTPases Activate ROCKs 18/4500 20/10654 1.2323774625728174e-5 3.094242693797937e-5 1.2365771585830997e-5 388/79784/9475/4628/6093/1072/4659/389/5500/10627/387/5058/4629/3984/4627/10398/4637/103910 18 Varicella.zoster_virus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 13/4500 13/10654 1.3481671003054578e-5 3.325161257997207e-5 1.3288610064383351e-5 2064/9542/7314/2065/9101/10000/6233/10193/3084/208/7311/207/7316 13 Varicella.zoster_virus R-HSA-179812 GRB2 events in EGFR signaling 13/4500 13/10654 1.3481671003054578e-5 3.325161257997207e-5 1.3288610064383351e-5 374/4893/7039/2885/3845/3265/1839/2069/255324/6654/1956/685/1950 13 Varicella.zoster_virus R-HSA-190375 FGFR2c ligand binding and activation 13/4500 13/10654 1.3481671003054578e-5 3.325161257997207e-5 1.3288610064383351e-5 2250/2253/8823/8074/2249/2247/2246/2251/2263/8822/8817/2254/26281 13 Varicella.zoster_virus R-HSA-202670 ERKs are inactivated 13/4500 13/10654 1.3481671003054578e-5 3.325161257997207e-5 1.3288610064383351e-5 1848/5518/51231/5515/1849/5594/5528/5519/5598/1846/5595/5516/1845 13 Varicella.zoster_virus R-HSA-209560 NF-kB is activated and signals survival 13/4500 13/10654 1.3481671003054578e-5 3.325161257997207e-5 1.3288610064383351e-5 4790/8878/4792/3654/3551/7314/5970/6233/7189/7311/4804/7316/4803 13 Varicella.zoster_virus R-HSA-5357786 TNFR1-induced proapoptotic signaling 13/4500 13/10654 1.3481671003054578e-5 3.325161257997207e-5 1.3288610064383351e-5 7124/7375/1540/8737/841/7128/8772/8717/27005/7186/56957/7132/9099 13 Varicella.zoster_virus R-HSA-5654227 Phospholipase C-mediated cascade; FGFR3 13/4500 13/10654 1.3481671003054578e-5 3.325161257997207e-5 1.3288610064383351e-5 2250/5335/2253/8823/8074/2249/2247/2246/8822/8817/2254/26281/2261 13 Varicella.zoster_virus R-HSA-5658623 FGFRL1 modulation of FGFR1 signaling 13/4500 13/10654 1.3481671003054578e-5 3.325161257997207e-5 1.3288610064383351e-5 2250/2253/8074/2249/2248/2247/200734/53834/8822/8817/2255/27006/161742 13 Varicella.zoster_virus R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 13/4500 13/10654 1.3481671003054578e-5 3.325161257997207e-5 1.3288610064383351e-5 7531/10971/7533/2810/11200/7465/7534/983/7532/891/1111/7529/995 13 Varicella.zoster_virus R-HSA-8847993 ERBB2 Activates PTK6 Signaling 13/4500 13/10654 1.3481671003054578e-5 3.325161257997207e-5 1.3288610064383351e-5 2064/5753/145957/9542/1839/2065/2069/3084/10718/1956/685/1950/2066 13 Varicella.zoster_virus R-HSA-167287 HIV elongation arrest and recovery 28/4500 36/10654 1.4937337784964626e-5 3.664766880107314e-5 1.4645803396598376e-5 5431/5435/5433/5439/11198/904/51497/5438/1025/7936/6829/25920/2963/5434/5436/2962/8812/905/5432/6917/5440/5430/6749/5441/9150/5437/6827/8178 28 Varicella.zoster_virus R-HSA-167290 Pausing and recovery of HIV elongation 28/4500 36/10654 1.4937337784964626e-5 3.664766880107314e-5 1.4645803396598376e-5 5431/5435/5433/5439/11198/904/51497/5438/1025/7936/6829/25920/2963/5434/5436/2962/8812/905/5432/6917/5440/5430/6749/5441/9150/5437/6827/8178 28 Varicella.zoster_virus R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 28/4500 36/10654 1.4937337784964626e-5 3.664766880107314e-5 1.4645803396598376e-5 71/51517/10094/8976/2885/5879/25/10093/10006/5594/10810/23191/10109/5747/10092/10163/55845/998/695/10097/60/5595/4690/10458/10552/10096/7454/10095 28 Varicella.zoster_virus R-HSA-381119 Unfolded Protein Response (UPR) 60/4500 94/10654 1.854784130712115e-5 4.54259411662125e-5 1.815393516671138e-5 10525/1965/1663/5526/811/3576/9570/10130/3309/4801/6745/6347/11340/9820/10488/8720/9695/84699/7094/9114/58477/468/22872/51726/3068/1054/8894/9451/2931/64061/8570/23016/148327/118460/1968/1200/6464/7184/118/1051/84447/4800/1639/10954/90993/51010/64764/167227/22894/4000/10113/440/4802/1649/2081/30827/467/51360/54512/7709 60 Varicella.zoster_virus R-HSA-400685 Sema4D in semaphorin signaling 21/4500 25/10654 2.1825927395367178e-5 5.3267473153728285e-5 2.1287709826177042e-5 2909/388/2064/23365/79784/9475/4628/6093/10507/5879/389/10627/4233/387/4629/3984/4627/10398/4637/103910/6237 21 Varicella.zoster_virus R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 21/4500 25/10654 2.1825927395367178e-5 5.3267473153728285e-5 2.1287709826177042e-5 22938/1387/9794/9787/388585/23286/2648/55534/3280/84441/4854/10320/8850/5087/10046/6772/23493/4851/23462/2033/3516 21 Varicella.zoster_virus R-HSA-73887 Death Receptor Signalling 84/4500 141/10654 2.2594642111746557e-5 5.504733052006665e-5 2.199900857761675e-5 7124/7984/4790/7531/29/356/7375/9530/8878/1894/4792/836/23365/10616/26230/3654/6868/8997/26084/8874/1540/3551/7314/5879/9181/90268/8737/55072/841/8517/6453/9828/5970/5664/8797/7128/396/10454/3066/6233/7410/7409/26574/8772/331/8717/5663/84894/445328/572/7074/330/10451/27005/843/8837/7189/6654/7311/387/6655/8795/5924/1147/4804/8841/7186/56957/6885/5584/10018/57580/8793/9459/355/23421/4615/7316/7132/329/9099/4803/3065/5599 84 Varicella.zoster_virus R-HSA-110312 Translesion synthesis by REV1 15/4500 16/10654 2.3192967311903213e-5 5.5726992026535084e-5 2.227062718599276e-5 5982/6117/7314/6118/51455/5985/5984/6233/5111/6119/7311/5983/7316/5981/5980 15 Varicella.zoster_virus R-HSA-1295596 Spry regulation of FGF signaling 15/4500 16/10654 2.3192967311903213e-5 5.5726992026535084e-5 2.227062718599276e-5 2885/5518/7314/5515/5594/6714/6233/5781/673/7311/5595/5516/10253/7316/867 15 Varicella.zoster_virus R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 15/4500 16/10654 2.3192967311903213e-5 5.5726992026535084e-5 2.227062718599276e-5 1869/5928/7027/5934/890/983/286826/91750/1874/55957/4605/1875/5933/3065/132660 15 Varicella.zoster_virus R-HSA-1433559 Regulation of KIT signaling 15/4500 16/10654 2.3192967311903213e-5 5.5726992026535084e-5 2.227062718599276e-5 5777/5578/2534/2885/3815/9306/6714/7525/3932/10019/8651/4067/6654/867/4254 15 Varicella.zoster_virus R-HSA-193639 p75NTR signals via NF-kB 15/4500 16/10654 2.3192967311903213e-5 5.5726992026535084e-5 2.227062718599276e-5 4790/8878/4792/3654/3551/7314/5970/6233/7189/7311/4804/5584/4615/7316/4803 15 Varicella.zoster_virus R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 15/4500 16/10654 2.3192967311903213e-5 5.5726992026535084e-5 2.227062718599276e-5 5295/5291/2534/2885/9846/5290/5170/6464/2205/2206/6850/4067/6654/5296/2207 15 Varicella.zoster_virus R-HSA-5654219 Phospholipase C-mediated cascade: FGFR1 15/4500 16/10654 2.3192967311903213e-5 5.5726992026535084e-5 2.227062718599276e-5 2250/5335/2253/8074/2260/2249/2248/2247/2246/2251/8822/2254/26281/2255/27006 15 Varicella.zoster_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 15/4500 16/10654 2.3192967311903213e-5 5.5726992026535084e-5 2.227062718599276e-5 8454/4790/3551/7314/8945/8517/6233/79155/7311/6416/1147/5604/6500/7316/23291 15 Varicella.zoster_virus R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 19/4500 22/10654 2.5207087738179797e-5 6.035865262864322e-5 2.412161506045914e-5 3725/7531/356/7001/4001/826/823/2801/993/351/6648/1020/4000/994/2309/10018/995/8851/5052 19 Varicella.zoster_virus R-HSA-8863678 Neurodegenerative Diseases 19/4500 22/10654 2.5207087738179797e-5 6.035865262864322e-5 2.412161506045914e-5 3725/7531/356/7001/4001/826/823/2801/993/351/6648/1020/4000/994/2309/10018/995/8851/5052 19 Varicella.zoster_virus R-HSA-2424491 DAP12 signaling 24/4500 30/10654 2.6927528997002634e-5 6.436786041064328e-5 2.5723847095189977e-5 5295/4893/5335/5291/567/2534/2885/3133/3845/3265/5879/5290/5336/7410/3932/6464/3937/10451/6850/695/6654/9402/27040/5296 24 Varicella.zoster_virus R-HSA-111932 CaMK IV-mediated phosphorylation of CREB 12/4500 12/10654 3.196790169663702e-5 7.525664547808648e-5 3.007542007494031e-5 817/814/818/801/805/3838/10645/84254/816/815/1385/808 12 Varicella.zoster_virus R-HSA-170968 Frs2-mediated activation 12/4500 12/10654 3.196790169663702e-5 7.525664547808648e-5 3.007542007494031e-5 5605/1399/5594/4914/673/2889/7529/5595/5604/10818/4803/5906 12 Varicella.zoster_virus R-HSA-1839130 Signaling by activated point mutants of FGFR3 12/4500 12/10654 3.196790169663702e-5 7.525664547808648e-5 3.007542007494031e-5 2250/2253/8823/8074/2249/2247/2246/8822/8817/2254/26281/2261 12 Varicella.zoster_virus R-HSA-190873 Gap junction degradation 12/4500 12/10654 3.196790169663702e-5 7.525664547808648e-5 3.007542007494031e-5 71/1212/1785/2697/1759/4646/1601/1213/1211/1173/8218/60 12 Varicella.zoster_virus R-HSA-2029481 FCGR activation 12/4500 12/10654 3.196790169663702e-5 7.525664547808648e-5 3.007542007494031e-5 2268/2534/6714/7525/2214/2209/6850/4067/919/3055/917/2212 12 Varicella.zoster_virus R-HSA-2033514 FGFR3 mutant receptor activation 12/4500 12/10654 3.196790169663702e-5 7.525664547808648e-5 3.007542007494031e-5 2250/2253/8823/8074/2249/2247/2246/8822/8817/2254/26281/2261 12 Varicella.zoster_virus R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 12/4500 12/10654 3.196790169663702e-5 7.525664547808648e-5 3.007542007494031e-5 7159/23368/8797/7157/8626/7161/8795/8793/3486/355/8794/124446 12 Varicella.zoster_virus R-HSA-8984722 Interleukin-35 Signalling 12/4500 12/10654 3.196790169663702e-5 7.525664547808648e-5 3.007542007494031e-5 3717/3572/10148/3592/7297/6775/3595/821/6774/6772/3716/9466 12 Varicella.zoster_virus R-HSA-9020558 Interleukin-2 signaling 12/4500 12/10654 3.196790169663702e-5 7.525664547808648e-5 3.007542007494031e-5 6776/3558/3718/3932/6777/6464/6850/3716/2185/3561/3560/3559 12 Varicella.zoster_virus R-HSA-199977 ER to Golgi Anterograde Transport 90/4500 154/10654 3.323619217732622e-5 7.8110646935265e-5 3.121598769091423e-5 6811/23256/374/6711/126003/51807/10484/7039/347688/5861/10381/1780/9570/8655/832/3998/7846/9382/3630/6709/10652/54732/51164/58485/10342/4253/2801/10466/22872/1315/8615/11316/91949/8729/1314/10540/51332/27095/378/6396/1453/140735/10959/22820/84617/11258/6712/2890/1783/10382/10802/830/7277/10671/9554/966/1639/6710/8775/81876/51143/51693/23243/5537/9871/10383/84790/7280/829/1778/9919/10113/11070/25839/1781/57731/10121/2804/9527/57511/22870/10972/381/6708/4905/9276/287/375/64689/22818 90 Varicella.zoster_virus R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 28/4500 37/10654 3.6627862982304365e-5 8.593696928285192e-5 3.434368399933006e-5 79718/27327/9612/55818/6907/192669/4343/1071/10062/344/348/6257/26523/19/27161/8841/347/57690/192670/9611/2874/2033/221656/23028/6256/23112/7376/8648 28 Varicella.zoster_virus R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 25/4500 32/10654 3.815405944001448e-5 8.921786763527674e-5 3.5654855863894344e-5 51807/10381/10576/7846/7411/10574/10693/5201/5204/10575/10471/5202/84617/10382/7277/10383/60/84790/22948/7280/10694/5203/7203/908/6950 25 Varicella.zoster_virus R-HSA-5626467 RHO GTPases activate IQGAPs 25/4500 32/10654 3.815405944001448e-5 8.921786763527674e-5 3.5654855863894344e-5 71/6249/51807/347688/10381/7846/8826/5879/999/128239/801/4221/805/84617/10382/7277/998/10788/10383/60/84790/7280/1495/1499/808 25 Varicella.zoster_virus R-HSA-933542 TRAF6 mediated NF-kB activation 20/4500 24/10654 4.379235175665961e-5 1.0223097500384084e-4 4.085538889461292e-5 4790/4792/177/64135/3551/4214/8517/5970/23586/4791/351/7706/7189/1147/7186/57506/4793/3146/6288/6285 20 Varicella.zoster_virus R-HSA-76009 Platelet Aggregation (Plug Formation) 29/4500 39/10654 4.659407673485899e-5 1.0858986831696686e-4 4.339664470516697e-5 5770/5908/2244/3690/2885/9564/7094/10125/6714/2335/1445/2266/2243/5170/6464/5747/3674/1277/6850/6654/7450/7066/207/54518/4352/1398/10235/5906/1278 29 Varicella.zoster_virus R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 26/4500 34/10654 5.13783595456399e-5 1.1934141418587904e-4 4.76933716773608e-5 5431/5435/5433/5439/11198/904/51497/5438/1025/7936/6829/25920/2963/5434/5436/2962/5432/6917/5440/5430/6749/5441/9150/5437/6827/8178 26 Varicella.zoster_virus R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 26/4500 34/10654 5.13783595456399e-5 1.1934141418587904e-4 4.76933716773608e-5 5431/5435/5433/5439/11198/904/51497/5438/1025/7936/6829/25920/2963/5434/5436/2962/5432/6917/5440/5430/6749/5441/9150/5437/6827/8178 26 Varicella.zoster_virus R-HSA-933541 TRAF6 mediated IRF7 activation 23/4500 29/10654 5.1538547502017823e-5 1.1951463839338352e-4 4.7762598664223556e-5 3443/1387/64135/3445/29110/3444/23586/3451/3448/3661/3439/3452/3446/3665/7706/3440/7189/3456/3441/7186/57506/3449/2033 23 Varicella.zoster_virus R-HSA-5099900 WNT5A-dependent internalization of FZD4 14/4500 15/10654 5.1716977327632944e-5 1.1953129196916489e-4 4.776925406700151e-5 5579/5578/1212/163/161/1856/8322/7474/1213/1211/1175/1173/409/160 14 Varicella.zoster_virus R-HSA-5358508 Mismatch Repair 14/4500 15/10654 5.1716977327632944e-5 1.1953129196916489e-4 4.776925406700151e-5 4436/9156/6117/10714/6118/3978/5424/2956/4292/5425/5111/6119/57804/5395 14 Varicella.zoster_virus R-HSA-5218921 VEGFR2 mediated cell proliferation 18/4500 21/10654 5.195202832363015e-5 1.1987608518973172e-4 4.79070465620252e-5 4893/5335/5579/5578/3845/3265/8877/5921/6714/5580/3791/801/805/5170/5590/7422/10768/808 18 Varicella.zoster_virus R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 16/4500 18/10654 5.634598533250997e-5 1.298003226471682e-4 5.187314960262339e-5 4893/5578/2885/6196/6197/3845/3265/1839/5594/5598/6195/6654/1956/5595/4314/1385 16 Varicella.zoster_virus R-HSA-983231 Factors involved in megakaryocyte development and platelet production 96/4500 168/10654 6.274319479405323e-5 1.4429901142091981e-4 5.76673775094914e-5 3443/11311/51807/347688/55619/10381/832/285643/3043/10112/3717/7846/11004/10749/7465/81930/5879/3445/25/5868/23348/23186/5567/29127/3444/5573/91768/50808/3796/23414/3451/55614/3448/56992/3066/7157/3439/55669/3835/3833/3452/9493/81704/3660/3446/9732/3831/84617/85440/9585/10019/10382/5568/830/3832/7277/23303/2623/3659/5566/2627/1062/3440/4602/998/7975/5577/10383/24137/60/25942/84790/84643/3456/1020/7280/829/55582/11216/1017/23468/3441/2624/5575/2625/25970/3449/81928/3705/5576/547/3065/23028/55083/51317/10938 96 Varicella.zoster_virus R-HSA-5693538 Homology Directed Repair 81/4500 138/10654 6.554791281347418e-5 1.505014577098848e-4 6.014611113424744e-5 2237/83990/151987/9156/1763/7486/5982/472/6613/4683/165918/84126/8900/8924/2067/672/6117/7334/10714/348654/83695/7314/6118/25/5888/51588/51720/63967/5531/116028/890/9656/5985/5984/6233/7158/6047/5884/5810/5424/80010/7515/54107/580/11073/5425/641/5111/6119/3364/10524/5427/144715/142/1111/7329/79728/51426/7311/3980/5983/56655/1017/5883/10111/57804/675/51548/545/7336/2072/29086/7316/5426/10635/7341/5932/9025/79184/7156/5981 81 Varicella.zoster_virus R-HSA-110373 Resolution of AP sites via the multiple-nucleotide patch replacement pathway 21/4500 26/10654 6.811889058032808e-5 1.5614773604291955e-4 6.240257887403663e-5 2237/5982/6117/10714/6118/328/3978/5985/5984/5424/54107/5425/5111/6119/5427/142/5983/56655/57804/5426/5981 21 Varicella.zoster_virus R-HSA-399719 Trafficking of AMPA receptors 24/4500 31/10654 7.137548907941142e-5 1.630772221847109e-4 6.517186529776564e-5 5579/23426/817/5578/9463/9495/1739/163/818/161/4646/1175/2891/1173/2890/2036/160/80852/816/10369/815/4905/1742/4193 24 Varicella.zoster_virus R-HSA-399721 Glutamate binding, activation of AMPA receptors and synaptic plasticity 24/4500 31/10654 7.137548907941142e-5 1.630772221847109e-4 6.517186529776564e-5 5579/23426/817/5578/9463/9495/1739/163/818/161/4646/1175/2891/1173/2890/2036/160/80852/816/10369/815/4905/1742/4193 24 Varicella.zoster_virus R-HSA-1059683 Interleukin-6 signaling 11/4500 11/10654 7.579291106199758e-5 1.6983451660120165e-4 6.787233735382061e-5 9021/3717/3569/3572/3570/7297/5781/6774/6772/3716/867 11 Varicella.zoster_virus R-HSA-174414 Processive synthesis on the C-strand of the telomere 11/4500 11/10654 7.579291106199758e-5 1.6983451660120165e-4 6.787233735382061e-5 2237/1763/6117/10714/6118/3978/5424/5425/5111/6119/57804 11 Varicella.zoster_virus R-HSA-1839122 Signaling by activated point mutants of FGFR1 11/4500 11/10654 7.579291106199758e-5 1.6983451660120165e-4 6.787233735382061e-5 2250/2253/8074/2260/2249/2247/2246/2251/8822/2254/26281 11 Varicella.zoster_virus R-HSA-196025 Formation of annular gap junctions 11/4500 11/10654 7.579291106199758e-5 1.6983451660120165e-4 6.787233735382061e-5 71/1212/1785/2697/1759/1601/1213/1211/1173/8218/60 11 Varicella.zoster_virus R-HSA-2514853 Condensation of Prometaphase Chromosomes 11/4500 11/10654 7.579291106199758e-5 1.6983451660120165e-4 6.787233735382061e-5 1459/1460/1457/64151/10051/983/23397/9133/891/10592/9918 11 Varicella.zoster_virus R-HSA-2586552 Signaling by Leptin 11/4500 11/10654 7.579291106199758e-5 1.6983451660120165e-4 6.787233735382061e-5 3953/9021/6776/3717/8660/3667/3952/6777/5781/6774/25970 11 Varicella.zoster_virus R-HSA-5655291 Signaling by FGFR4 in disease 11/4500 11/10654 7.579291106199758e-5 1.6983451660120165e-4 6.787233735382061e-5 5295/4893/5335/2264/2885/3845/3265/5290/6654/2549/10818 11 Varicella.zoster_virus R-HSA-68689 CDC6 association with the ORC:origin complex 11/4500 11/10654 7.579291106199758e-5 1.6983451660120165e-4 6.787233735382061e-5 1869/84515/4998/990/5001/23594/4999/5000/1870/23595/1871 11 Varicella.zoster_virus R-HSA-8851805 MET activates RAS signaling 11/4500 11/10654 7.579291106199758e-5 1.6983451660120165e-4 6.787233735382061e-5 4893/3082/2885/3845/3265/57610/6464/4233/6654/10048/200958 11 Varicella.zoster_virus R-HSA-8875555 MET activates RAP1 and RAC1 11/4500 11/10654 7.579291106199758e-5 1.6983451660120165e-4 6.787233735382061e-5 5908/3082/2885/1399/5879/85440/4233/2889/2549/1398/5906 11 Varicella.zoster_virus R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 11/4500 11/10654 7.579291106199758e-5 1.6983451660120165e-4 6.787233735382061e-5 627/4893/2885/3845/3265/4909/5781/6654/4915/10817/10818 11 Varicella.zoster_virus R-HSA-9614399 Regulation of localization of FOXO transcription factors 11/4500 11/10654 7.579291106199758e-5 1.6983451660120165e-4 6.787233735382061e-5 2308/10971/2810/7534/10000/7532/4303/208/7529/2309/207 11 Varicella.zoster_virus R-HSA-195721 Signaling by WNT 174/4500 331/10654 7.701068211970291e-5 1.7228671833189945e-4 6.88523305051325e-5 8454/27123/9070/5689/857/5579/5682/5331/1459/5526/1452/5578/1212/5929/27327/1460/55737/143471/5705/6657/8452/5530/5709/9978/5695/1457/9559/4609/5881/5711/1387/5683/5699/8724/8312/2782/5702/192669/57216/1855/163/79412/5518/4343/25776/3845/6659/5696/5691/4920/7314/5879/5515/2787/5718/51176/8945/161/6662/79971/51701/5700/122706/5707/1856/1454/8322/23198/9101/7471/7534/5528/7091/89780/51699/9861/5519/2932/5698/5692/5713/2783/2784/5710/5719/6233/7474/1857/7514/4040/1213/1211/331/8607/1175/26523/801/4221/805/123169/1173/144165/6597/864/4772/10023/409/79577/5706/160/5714/6934/10524/5688/5687/4919/23236/5708/5529/208/57680/5704/7311/387/5694/5516/57154/27161/815/5684/8295/5720/7015/6885/1487/1499/5525/59345/207/8085/5690/5532/57690/27121/5717/9491/6500/10197/192670/64750/7316/10213/55970/5216/5715/5701/1455/5685/5686/2033/54894/5534/3065/23112/23513/5527/1488/5716/23072/808/9736/5693/5721/6259 174 Varicella.zoster_virus R-HSA-111996 Ca-dependent events 28/4500 38/10654 8.307852005580114e-5 1.855641823966374e-4 7.415851053402039e-5 817/5578/814/818/5567/5594/112/5573/5580/5153/115/801/805/3838/5568/10645/5566/84254/816/5577/815/5321/5575/114/5576/1385/808/5137 28 Varicella.zoster_virus R-HSA-2132295 MHC class II antigen presentation 73/4500 123/10654 9.02526883417972e-5 2.0126637847467876e-4 8.043370576955191e-5 162/51807/10484/1174/347688/1785/10381/1780/3115/1509/8655/832/285643/10112/7846/5476/6456/11004/163/1759/3127/81930/51164/161/10053/29127/22872/3796/56992/10540/3835/1213/1211/9493/6396/1175/7879/140735/8907/3831/1173/84617/11258/6712/1783/10382/10802/821/830/3123/3832/7277/160/10671/3122/1639/26052/1062/51143/9871/10383/24137/84790/84643/8905/7280/829/1778/164/10120/1781/10121/375 73 Varicella.zoster_virus R-HSA-8856688 Golgi-to-ER retrograde transport 78/4500 133/10654 9.236316238535046e-5 2.0564429775111524e-4 8.218328895196131e-5 51807/53407/347688/5861/10381/1780/5048/8655/832/285643/10112/636/7846/11004/10749/81930/54732/51164/29127/23299/1315/3796/5870/11316/55614/56992/8729/1314/10540/3835/3833/378/9493/140735/10959/3831/22820/84617/11258/1783/55850/9585/10382/830/3832/7277/10671/9554/23303/1639/8775/81876/9183/1062/51143/10383/24137/84790/84643/5049/7280/829/22931/1778/55582/5321/5050/1781/10121/6836/547/10972/381/4905/9276/55083/375/22818 78 Varicella.zoster_virus R-HSA-429914 Deadenylation-dependent mRNA decay 38/4500 56/10654 9.269830010129124e-5 2.0606182633981304e-4 8.235014926866303e-5 80153/26986/25904/1973/10767/55571/11340/57472/85456/29883/80349/51690/11157/1981/1977/23016/118460/9924/27258/4850/9652/57819/246175/4848/23019/23658/1975/51010/1974/167227/22894/1656/4849/25804/9337/9775/6499/54512 38 Varicella.zoster_virus R-HSA-5357905 Regulation of TNFR1 signaling 25/4500 33/10654 9.415071508525716e-5 2.0895770788397294e-4 8.350745376150332e-5 7124/7375/10616/1540/3551/7314/90268/8737/55072/841/8517/7128/6233/331/8717/330/27005/7311/1147/7186/56957/7316/7132/329/9099 25 Varicella.zoster_virus R-HSA-190241 FGFR2 ligand binding and activation 17/4500 20/10654 1.0632485645117789e-4 2.3560238032673705e-4 9.415567906286431e-5 2250/2252/2253/8823/8074/2249/2248/2247/2246/2251/2263/8822/8817/2254/26281/2255/27006 17 Varicella.zoster_virus R-HSA-9012852 Signaling by NOTCH3 34/4500 49/10654 1.0894411322410321e-4 2.4102374336109047e-4 9.632226208820538e-5 4904/182/22938/1387/9794/9787/388585/7314/23286/2648/55534/3280/84441/4854/102/5664/10320/8850/5087/6233/5663/10460/10046/6772/23493/7311/1956/4851/23462/7316/1950/2033/54567/3516 34 Varicella.zoster_virus R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 13/4500 14/10654 1.1484062632552166e-4 2.5167584670396896e-4 1.0057924804185159e-4 5861/2801/5594/983/8548/8615/9133/891/81876/5347/5595/26003/64689 13 Varicella.zoster_virus R-HSA-177504 Retrograde neurotrophin signalling 13/4500 14/10654 1.1484062632552166e-4 2.5167584670396896e-4 1.0057924804185159e-4 1785/6456/163/1759/161/4914/1213/1211/1175/1173/160/26052/4803 13 Varicella.zoster_virus R-HSA-198323 AKT phosphorylates targets in the cytosol 13/4500 14/10654 1.1484062632552166e-4 2.5167584670396896e-4 1.0057924804185159e-4 7249/2932/10000/2931/23608/572/208/1147/842/207/1027/1026/4193 13 Varicella.zoster_virus R-HSA-3371568 Attenuation phase 13/4500 14/10654 1.1484062632552166e-4 2.5167584670396896e-4 1.0057924804185159e-4 3305/1387/3306/3312/3303/3337/3297/3326/3304/10728/3320/2033/2288 13 Varicella.zoster_virus R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 13/4500 14/10654 1.1484062632552166e-4 2.5167584670396896e-4 1.0057924804185159e-4 4436/9156/6117/10714/6118/3978/5424/4292/5425/5111/6119/57804/5395 13 Varicella.zoster_virus R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 13/4500 14/10654 1.1484062632552166e-4 2.5167584670396896e-4 1.0057924804185159e-4 79370/7159/23368/332/64065/7157/604/5875/8626/7161/10397/9540/5876 13 Varicella.zoster_virus R-HSA-9034015 Signaling by NTRK3 (TRKC) 15/4500 17/10654 1.1942061080170506e-4 2.608938539580286e-4 1.0426311461148784e-4 5295/4893/5335/2885/3845/3265/5290/3667/6714/25920/4908/6464/6654/4916/581 15 Varicella.zoster_virus R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 15/4500 17/10654 1.1942061080170506e-4 2.608938539580286e-4 1.0426311461148784e-4 2308/857/2290/57060/4089/1647/4088/5934/4303/901/9314/4087/2309/1027/1026 15 Varicella.zoster_virus R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 77/4500 132/10654 1.304032845481975e-4 2.8444216442075575e-4 1.1367391580681689e-4 83990/151987/9156/1763/7486/5982/472/6613/4683/165918/84126/8900/8924/2067/672/6117/7334/10714/348654/83695/7314/6118/25/5888/51588/51720/63967/5531/116028/890/9656/5985/5984/6233/7158/6047/5884/5810/5424/80010/54107/580/11073/5425/641/5111/6119/3364/10524/5427/144715/1111/7329/79728/51426/7311/5983/56655/1017/5883/10111/57804/675/51548/545/7336/2072/29086/7316/5426/10635/7341/5932/9025/79184/7156/5981 77 Varicella.zoster_virus R-HSA-71291 Metabolism of amino acids and derivatives 192/4500 372/10654 1.30685961008338e-4 2.8461404300723843e-4 1.1374260503230012e-4 6158/6470/5689/6138/11019/6227/6206/6234/6191/1373/6128/5682/6132/6129/3620/5160/2806/383/6224/6146/6154/143471/6202/5705/8050/6169/5709/6175/6218/5695/6173/6167/5711/4946/5683/6156/5699/6143/5702/6139/10295/3921/3176/29968/6208/5696/5691/6535/7296/5718/6203/1728/29920/6147/5700/122706/5707/4143/191/6222/4837/2184/2936/8528/23198/1737/6134/60678/6723/6155/84706/6231/9861/6142/9061/2752/162417/5832/5698/8604/5692/5713/5162/5710/26227/6207/5719/196743/6233/7306/1610/587/501/6188/189/6303/2744/200916/6122/4942/6230/152926/6194/3028/1743/6136/51601/2805/6125/51151/5706/6232/6160/7299/5714/6193/8140/6210/6229/6205/5688/5687/5708/55526/140801/6235/6181/54363/5704/7311/6223/25873/36/5694/9045/6187/6168/2746/6157/6137/440/6144/5684/27165/9349/4736/5720/51121/6217/51268/6152/5690/55349/5717/9491/11185/51065/6141/10197/875/6164/10213/10165/6209/11224/6165/6130/5715/6204/5701/6228/51540/1152/23474/5685/7965/5686/6124/6520/2346/5716/1738/4507/548596/6189/6135/5860/6201/6161/5693/5721/6133 192 Varicella.zoster_virus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 23/4500 30/10654 1.3240332258992538e-4 2.8790504413634863e-4 1.1505781435097632e-4 11065/7321/8239/3093/7347/7328/7332/7314/90268/29089/7324/6233/7874/7317/7327/7311/997/7319/7320/7316/54926/7322/27338 23 Varicella.zoster_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 37/4500 55/10654 1.5119113351041785e-4 3.282470021470347e-4 1.3117999633383232e-4 834/4790/7295/1432/10628/5603/83737/3654/7334/1540/3551/7314/841/8517/5970/24145/7128/837/598/10454/6233/5600/6300/5608/4791/351/330/7189/3326/7311/1147/596/6885/842/58484/7316/329 37 Varicella.zoster_virus R-HSA-6784531 tRNA processing in the nucleus 38/4500 57/10654 1.6529887453080585e-4 3.5831867833075305e-4 1.4319778277431695e-4 23165/348995/57122/23511/11260/23279/23225/79074/9972/8021/55746/60528/10762/1478/79902/9883/1653/6396/129401/4928/5903/55706/7175/4927/10898/5901/8086/81929/9631/29894/79023/23636/53371/10978/283742/9688/51493/8480 38 Varicella.zoster_virus R-HSA-1251985 Nuclear signaling by ERBB4 24/4500 32/10654 1.7103977799760327e-4 3.679068260164163e-4 1.4702957154931432e-4 2670/51741/6776/10413/145957/6868/9542/6387/1839/2069/348/6714/2099/5664/1447/3925/5663/5241/3084/10718/685/9611/2066/6285 24 Varicella.zoster_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 24/4500 32/10654 1.7103977799760327e-4 3.679068260164163e-4 1.4702957154931432e-4 4738/4089/23327/4088/5499/7040/7314/4092/11171/9958/9040/6233/7514/5500/5501/4087/7048/7311/57154/51377/10273/64750/7316/867 24 Varicella.zoster_virus R-HSA-381042 PERK regulates gene expression 24/4500 32/10654 1.7103977799760327e-4 3.679068260164163e-4 1.4702957154931432e-4 1965/3576/3309/4801/6347/11340/468/1054/8894/9451/8570/23016/118460/1968/1051/4800/51010/167227/22894/440/4802/1649/467/54512 24 Varicella.zoster_virus R-HSA-73863 RNA Polymerase I Transcription Termination 24/4500 32/10654 1.7103977799760327e-4 3.679068260164163e-4 1.4702957154931432e-4 5435/2965/2967/30834/404672/2068/9533/5434/9015/4331/9013/2966/2071/6908/5440/902/9014/25885/5441/51082/7343/5437/2968/1022 24 Varicella.zoster_virus R-HSA-8941326 RUNX2 regulates bone development 24/4500 32/10654 1.7103977799760327e-4 3.679068260164163e-4 1.4702957154931432e-4 5925/9759/10413/4089/25/5594/3280/100526737/10013/2737/865/6714/7525/10432/1277/23493/367/860/5595/8841/23462/4086/4094/23314 24 Varicella.zoster_virus R-HSA-389357 CD28 dependent PI3K/Akt signaling 18/4500 22/10654 1.723042609581572e-4 3.694880926230222e-4 1.4766150587407768e-4 5295/941/2534/2475/5290/57761/9020/10000/3932/253260/5170/64223/8503/208/79109/207/942/5296 18 Varicella.zoster_virus R-HSA-9613829 Chaperone Mediated Autophagy 18/4500 22/10654 1.723042609581572e-4 3.694880926230222e-4 1.4766150587407768e-4 2670/1915/5116/3043/3920/3312/11315/7314/10013/123/6233/3326/7311/1080/7316/3320/200894/7431 18 Varicella.zoster_virus R-HSA-110056 MAPK3 (ERK1) activation 10/4500 10/10654 1.796747762458582e-4 3.783197400289865e-4 1.5119096834215266e-4 3717/3569/3572/983/3570/7297/5781/3716/5595/5604 10 Varicella.zoster_virus R-HSA-1250342 PI3K events in ERBB4 signaling 10/4500 10/10654 1.796747762458582e-4 3.783197400289865e-4 1.5119096834215266e-4 5295/145957/9542/1839/5290/2069/3084/10718/685/2066 10 Varicella.zoster_virus R-HSA-174437 Removal of the Flap Intermediate from the C-strand 10/4500 10/10654 1.796747762458582e-4 3.783197400289865e-4 1.5119096834215266e-4 2237/1763/6117/10714/6118/5424/5425/5111/6119/57804 10 Varicella.zoster_virus R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 10/4500 10/10654 1.796747762458582e-4 3.783197400289865e-4 1.5119096834215266e-4 5563/53632/1432/51422/5600/6300/5571/5564/5565/10891 10 Varicella.zoster_virus R-HSA-2465910 MASTL Facilitates Mitotic Progression 10/4500 10/10654 1.796747762458582e-4 3.783197400289865e-4 1.5119096834215266e-4 5518/55844/84930/5515/983/5519/2029/891/5516/10776 10 Varicella.zoster_virus R-HSA-390450 Folding of actin by CCT/TriC 10/4500 10/10654 1.796747762458582e-4 3.783197400289865e-4 1.5119096834215266e-4 10576/10574/10693/10575/60/22948/10694/7203/908/6950 10 Varicella.zoster_virus R-HSA-442729 CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde 10/4500 10/10654 1.796747762458582e-4 3.783197400289865e-4 1.5119096834215266e-4 814/818/801/805/3838/10645/84254/816/1385/808 10 Varicella.zoster_virus R-HSA-450341 Activation of the AP-1 family of transcription factors 10/4500 10/10654 1.796747762458582e-4 3.783197400289865e-4 1.5119096834215266e-4 3725/1432/1386/5601/5594/2353/5600/5602/5595/5599 10 Varicella.zoster_virus R-HSA-74749 Signal attenuation 10/4500 10/10654 1.796747762458582e-4 3.783197400289865e-4 1.5119096834215266e-4 3643/3630/2885/8660/3667/5594/6464/6654/5595/2887 10 Varicella.zoster_virus R-HSA-8853334 Signaling by FGFR3 fusions in cancer 10/4500 10/10654 1.796747762458582e-4 3.783197400289865e-4 1.5119096834215266e-4 5295/4893/2885/3845/3265/5290/6654/2549/10818/2261 10 Varicella.zoster_virus R-HSA-9020958 Interleukin-21 signaling 10/4500 10/10654 1.796747762458582e-4 3.783197400289865e-4 1.5119096834215266e-4 6776/50615/3718/6777/59067/6775/6774/6772/3716/3561 10 Varicella.zoster_virus R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 10/4500 10/10654 1.796747762458582e-4 3.783197400289865e-4 1.5119096834215266e-4 2308/7295/1387/10628/23411/8850/4303/23410/2309/2033 10 Varicella.zoster_virus R-HSA-3247509 Chromatin modifying enzymes 145/4500 274/10654 1.988613986742845e-4 4.174594173673701e-4 1.6683267320517735e-4 9070/1810/4790/79718/64769/51742/10474/9112/10445/5929/79813/7403/23338/84289/9612/6603/5926/27097/55818/5928/1387/56950/3717/6907/23512/1107/79084/57492/23133/22992/26610/6881/10499/1386/55689/3054/51230/10284/79723/54014/23774/84661/8464/9869/2648/23186/84193/2146/1788/51147/6871/23569/86/5970/51562/64426/8850/27154/57459/6604/8289/56943/6602/595/7994/8473/3066/23067/10419/8607/8726/6883/51780/10765/4791/55904/55683/84678/6595/1019/29943/23326/84148/7862/6597/9219/5931/6599/56970/11143/1108/2122/84444/10524/55578/54815/23210/55693/57504/58508/57634/6880/60/6601/6187/53615/4297/55140/10196/8295/8841/55167/55250/11091/5978/8085/6839/284058/6598/117143/10629/26009/9611/2874/10856/29072/80853/2033/6605/221656/3065/23028/23135/10498/9757/80854/51317/9739/10902/3276/9913/8648/64754/10919/54934 145 Varicella.zoster_virus R-HSA-4839726 Chromatin organization 145/4500 274/10654 1.988613986742845e-4 4.174594173673701e-4 1.6683267320517735e-4 9070/1810/4790/79718/64769/51742/10474/9112/10445/5929/79813/7403/23338/84289/9612/6603/5926/27097/55818/5928/1387/56950/3717/6907/23512/1107/79084/57492/23133/22992/26610/6881/10499/1386/55689/3054/51230/10284/79723/54014/23774/84661/8464/9869/2648/23186/84193/2146/1788/51147/6871/23569/86/5970/51562/64426/8850/27154/57459/6604/8289/56943/6602/595/7994/8473/3066/23067/10419/8607/8726/6883/51780/10765/4791/55904/55683/84678/6595/1019/29943/23326/84148/7862/6597/9219/5931/6599/56970/11143/1108/2122/84444/10524/55578/54815/23210/55693/57504/58508/57634/6880/60/6601/6187/53615/4297/55140/10196/8295/8841/55167/55250/11091/5978/8085/6839/284058/6598/117143/10629/26009/9611/2874/10856/29072/80853/2033/6605/221656/3065/23028/23135/10498/9757/80854/51317/9739/10902/3276/9913/8648/64754/10919/54934 145 Varicella.zoster_virus R-HSA-8875878 MET promotes cell motility 29/4500 41/10654 2.0622329752837358e-4 4.3161577713584634e-4 1.7249009341124914e-4 3675/5908/3082/3688/3910/2885/1399/5879/3918/284217/6714/2335/64759/84951/85440/5747/1277/3912/4233/2889/3913/2549/3915/1281/3673/3914/1398/5906/1278 29 Varicella.zoster_virus R-HSA-9609736 Assembly and cell surface presentation of NMDA receptors 29/4500 41/10654 2.0622329752837358e-4 4.3161577713584634e-4 1.7249009341124914e-4 51807/817/347688/10381/7846/1741/1739/1740/8825/818/2902/2906/4747/84617/8573/2904/10382/7277/55327/2905/816/10383/84790/7280/64130/815/2903/1742/88 29 Varicella.zoster_virus R-HSA-110320 Translesion Synthesis by POLH 16/4500 19/10654 2.1593024364165308e-4 4.512554193469277e-4 1.8033884199507741e-4 5982/25898/6117/55666/7314/6118/5985/5984/6233/5111/6119/7311/5983/7316/7415/5981 16 Varicella.zoster_virus R-HSA-75893 TNF signaling 30/4500 43/10654 2.372913876656686e-4 4.951551228419632e-4 1.978828344942245e-4 7124/7375/9530/10616/6868/1540/3551/7314/90268/8737/55072/841/8517/7128/10454/6233/8772/331/8717/330/27005/7311/1147/7186/56957/6885/7316/7132/329/9099 30 Varicella.zoster_virus R-HSA-390918 Peroxisomal lipid metabolism 22/4500 29/10654 2.434072914298907e-4 5.064032471477309e-4 2.0237801311136886e-4 26063/1384/23600/10005/390916/54677/26061/8309/10455/11001/5264/122970/51/55825/91452/1962/51179/6342/3295/8310/283927/224 22 Varicella.zoster_virus R-HSA-9619483 Activation of AMPK downstream of NMDARs 22/4500 29/10654 2.434072914298907e-4 5.064032471477309e-4 2.0237801311136886e-4 5563/51807/347688/53632/10381/7846/51422/801/805/84617/10382/7277/10645/5571/5562/10383/84790/5564/5565/7280/4137/808 22 Varicella.zoster_virus R-HSA-190242 FGFR1 ligand binding and activation 14/4500 16/10654 2.5138504743774207e-4 5.218093186265074e-4 2.085348656854539e-4 2250/2253/8074/2260/2249/2248/2247/2246/2251/8822/2254/26281/2255/27006 14 Varicella.zoster_virus R-HSA-8940973 RUNX2 regulates osteoblast differentiation 19/4500 24/10654 2.522307279767329e-4 5.218093186265074e-4 2.085348656854539e-4 5925/10413/25/5594/3280/10013/2737/865/6714/7525/1277/23493/367/860/5595/8841/23462/4094/23314 19 Varicella.zoster_virus R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 77/4500 134/10654 2.534462911348762e-4 5.218093186265074e-4 2.085348656854539e-4 5579/7042/5175/5578/3082/7423/3920/374354/2244/3309/3690/87/10487/7040/5874/54863/350/7043/5054/5099/1072/7018/813/7094/7414/10490/6810/7273/22927/1191/27154/226/2335/5478/94121/2266/5154/7076/2243/801/805/351/135228/7424/2316/3674/7277/334/10447/335/51706/308/197/81/9948/3481/54495/8407/7450/29789/10916/7422/1950/5216/6647/1893/7078/2/948/88/3479/5155/51368/808/213/7057/6814 77 Varicella.zoster_virus R-HSA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 12/4500 13/10654 2.5380267001962644e-4 5.218093186265074e-4 2.085348656854539e-4 5925/5422/1869/28227/5518/5558/5515/7027/5557/5519/23649/5516 12 Varicella.zoster_virus R-HSA-171007 p38MAPK events 12/4500 13/10654 2.5380267001962644e-4 5.218093186265074e-4 2.085348656854539e-4 4893/5898/1432/5603/3845/3265/5899/9261/6714/5600/6300/5900 12 Varicella.zoster_virus R-HSA-190239 FGFR3 ligand binding and activation 12/4500 13/10654 2.5380267001962644e-4 5.218093186265074e-4 2.085348656854539e-4 2250/2253/8823/8074/2249/2247/2246/8822/8817/2254/26281/2261 12 Varicella.zoster_virus R-HSA-190372 FGFR3c ligand binding and activation 12/4500 13/10654 2.5380267001962644e-4 5.218093186265074e-4 2.085348656854539e-4 2250/2253/8823/8074/2249/2247/2246/8822/8817/2254/26281/2261 12 Varicella.zoster_virus R-HSA-209543 p75NTR recruits signalling complexes 12/4500 13/10654 2.5380267001962644e-4 5.218093186265074e-4 2.085348656854539e-4 8878/3654/3551/7314/6233/7189/7311/4804/5584/4615/7316/4803 12 Varicella.zoster_virus R-HSA-111933 Calmodulin induced events 26/4500 36/10654 2.573691917221838e-4 5.26814357249514e-4 2.1053506962919808e-4 817/5578/814/818/5567/112/5573/5580/5153/115/801/805/3838/5568/10645/5566/84254/816/5577/815/5575/114/5576/1385/808/5137 26 Varicella.zoster_virus R-HSA-111997 CaM pathway 26/4500 36/10654 2.573691917221838e-4 5.26814357249514e-4 2.1053506962919808e-4 817/5578/814/818/5567/112/5573/5580/5153/115/801/805/3838/5568/10645/5566/84254/816/5577/815/5575/114/5576/1385/808/5137 26 Varicella.zoster_virus R-HSA-168638 NOD1/2 Signaling Pathway 26/4500 36/10654 2.573691917221838e-4 5.26814357249514e-4 2.1053506962919808e-4 834/1432/5603/83737/3654/7334/1540/3551/7314/841/8517/7128/837/10454/6233/5600/6300/5608/330/7189/7311/1147/6885/842/7316/329 26 Varicella.zoster_virus R-HSA-5689896 Ovarian tumor domain proteases 27/4500 38/10654 3.0349044226102046e-4 6.194044698777551e-4 2.47537602952202e-4 7321/64135/7314/8737/55611/8517/80124/983/2099/23586/7128/7157/6233/55593/10318/7706/79155/79589/7189/7311/387/56957/57506/7316/7415/5728/78990 27 Varicella.zoster_virus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 27/4500 38/10654 3.0349044226102046e-4 6.194044698777551e-4 2.47537602952202e-4 7039/51741/2064/5308/4609/1387/7913/7022/3815/348/2099/3329/10765/7020/4869/4839/10370/7329/29028/1956/7528/4605/7021/7422/1026/7341/2033 27 Varicella.zoster_virus R-HSA-8951664 Neddylation 125/4500 234/10654 3.227139261615597e-4 6.576768480606385e-4 2.628327020601255e-4 8454/5689/5682/80344/7321/9021/4738/9817/5929/3091/143471/5705/8452/5709/9978/5695/7704/10980/5711/7347/5683/23113/5699/10987/7428/5702/26094/25793/1154/92591/84961/5696/5691/9820/7314/51514/5718/8945/64410/23363/23038/5700/122706/5707/23198/332/7323/9306/4008/1643/9861/6502/55832/5698/5692/10920/5713/10238/5710/9040/5719/6233/83987/8835/11275/54939/10537/8451/899/9655/5931/5706/26263/8450/84078/5714/26272/5688/5687/26270/1161/5708/1642/5704/2873/7311/2034/51667/5694/51138/9318/5684/8065/5720/11091/25879/54850/5690/5717/9491/6500/26259/10197/7316/10213/114907/64708/7322/5715/5701/23291/5685/5686/55294/8453/123879/80176/8139/26043/5716/80204/8883/23014/5693/5721 125 Varicella.zoster_virus R-HSA-416572 Sema4D induced cell migration and growth-cone collapse 17/4500 21/10654 3.374093759932544e-4 6.866231616422494e-4 2.744007507694105e-4 388/2064/23365/79784/9475/4628/6093/10507/389/10627/387/4629/3984/4627/10398/4637/103910 17 Varicella.zoster_virus R-HSA-111885 Opioid Signalling 55/4500 91/10654 3.379408499248316e-4 6.867036775765137e-4 2.7443292800147207e-4 5331/2770/817/5578/5530/4988/2782/5499/5518/814/2773/5515/2787/818/5567/5594/112/5573/5528/5443/5519/2783/2784/2771/5580/5153/115/801/805/3838/5568/10645/5566/84254/23236/816/5577/1020/5516/5533/815/5321/5575/59345/5532/114/2779/55970/10768/5576/5534/1385/5144/808/5137 55 Varicella.zoster_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 20/4500 26/10654 3.434552446068322e-4 6.968946533010723e-4 2.785056298066418e-4 23327/4088/5499/7040/7314/4092/11171/9958/6233/7514/5500/5501/4087/7048/7311/57154/51377/10273/64750/7316 20 Varicella.zoster_virus R-HSA-69473 G2/M DNA damage checkpoint 57/4500 95/10654 3.473662425110246e-4 7.038073650876492e-4 2.8126821255953415e-4 83990/9156/1763/7531/7486/10971/5982/7533/2810/11200/472/4683/165918/84126/8924/672/6117/7334/7465/83695/6118/51588/51720/7534/116028/983/9656/5985/7157/5984/7158/5884/5810/80010/7532/580/11073/891/641/6119/3364/10524/144715/1111/5983/7529/5883/10111/545/7336/29086/7341/995/5932/9025/79184/7156 57 Varicella.zoster_virus R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 34/4500 51/10654 3.6241651976967647e-4 7.332369008673454e-4 2.9302937525237e-4 51807/347688/10381/1780/5048/8655/832/636/7846/51164/23299/5870/10540/140735/84617/11258/1783/10382/830/7277/10671/1639/51143/10383/84790/5049/7280/829/22931/1778/5321/5050/1781/10121 34 Varicella.zoster_virus R-HSA-1489509 DAG and IP3 signaling 29/4500 42/10654 3.98113928997336e-4 8.042938420843431e-4 3.2142643364854614e-4 5335/817/5578/814/818/5567/112/5573/5580/5153/115/801/805/3838/5568/10645/5566/84254/816/5577/815/5575/114/10768/5576/1385/5581/808/5137 29 Varicella.zoster_virus R-HSA-5693607 Processing of DNA double-strand break ends 58/4500 98/10654 5.094254280237348e-4 0.0010276848230074188 4.107019726993908e-4 83990/151987/9156/1763/7486/5982/472/6613/4683/165918/84126/8900/8924/672/6117/7334/83695/7314/6118/51588/51720/63967/5531/116028/890/9656/5985/5984/6233/7158/6047/5884/5810/80010/580/11073/641/6119/3364/10524/144715/1111/7329/7311/5983/1017/5883/10111/51548/545/7336/29086/7316/7341/5932/9025/79184/7156 58 Varicella.zoster_virus R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 13/4500 15/10654 5.251443448117984e-4 0.0010472878647961009 4.18536094361283e-4 5526/1452/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/5527 13 Varicella.zoster_virus R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 13/4500 15/10654 5.251443448117984e-4 0.0010472878647961009 4.18536094361283e-4 5526/1452/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/5527 13 Varicella.zoster_virus R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 13/4500 15/10654 5.251443448117984e-4 0.0010472878647961009 4.18536094361283e-4 5526/1452/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/5527 13 Varicella.zoster_virus R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 13/4500 15/10654 5.251443448117984e-4 0.0010472878647961009 4.18536094361283e-4 5526/1452/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/5527 13 Varicella.zoster_virus R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 13/4500 15/10654 5.251443448117984e-4 0.0010472878647961009 4.18536094361283e-4 5526/1452/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/5527 13 Varicella.zoster_virus R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 13/4500 15/10654 5.251443448117984e-4 0.0010472878647961009 4.18536094361283e-4 5526/1452/8312/5518/5515/5528/5519/2932/5529/5516/1499/5525/5527 13 Varicella.zoster_virus R-HSA-937039 IRAK1 recruits IKK complex 13/4500 15/10654 5.251443448117984e-4 0.0010472878647961009 4.18536094361283e-4 3654/7334/3551/7314/8517/6233/57162/7189/7311/1147/246330/7316/57161 13 Varicella.zoster_virus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 13/4500 15/10654 5.251443448117984e-4 0.0010472878647961009 4.18536094361283e-4 3654/7334/3551/7314/8517/6233/57162/7189/7311/1147/246330/7316/57161 13 Varicella.zoster_virus R-HSA-190373 FGFR1c ligand binding and activation 11/4500 12/10654 5.578680140809639e-4 0.001099977044713313 4.395926961982023e-4 2250/2253/8074/2260/2249/2247/2246/2251/8822/2254/26281 11 Varicella.zoster_virus R-HSA-210990 PECAM1 interactions 11/4500 12/10654 5.578680140809639e-4 0.001099977044713313 4.395926961982023e-4 5777/5335/5175/2534/3690/6714/7525/3685/3932/5781/4067 11 Varicella.zoster_virus R-HSA-2197563 NOTCH2 intracellular domain regulates transcription 11/4500 12/10654 5.578680140809639e-4 0.001099977044713313 4.395926961982023e-4 4853/9794/388585/55534/3280/84441/10046/2208/2033/1385/3516 11 Varicella.zoster_virus R-HSA-3371511 HSF1 activation 11/4500 12/10654 5.578680140809639e-4 0.001099977044713313 4.395926961982023e-4 7531/1915/6117/6118/10013/3297/6119/3326/10728/7415/3320 11 Varicella.zoster_virus R-HSA-389359 CD28 dependent Vav1 pathway 11/4500 12/10654 5.578680140809639e-4 0.001099977044713313 4.395926961982023e-4 941/2534/2885/5062/5879/7409/3932/5063/998/5058/942 11 Varicella.zoster_virus R-HSA-8866427 VLDLR internalisation and degradation 11/4500 12/10654 5.578680140809639e-4 0.001099977044713313 4.395926961982023e-4 163/10062/161/1213/1211/1175/29116/1173/160/255738/7376 11 Varicella.zoster_virus R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 11/4500 12/10654 5.578680140809639e-4 0.001099977044713313 4.395926961982023e-4 5295/5291/3717/2056/8660/5290/5294/2057/4067/5293/2549 11 Varicella.zoster_virus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 11/4500 12/10654 5.578680140809639e-4 0.001099977044713313 4.395926961982023e-4 64135/3551/8737/841/8517/23586/8772/7706/843/1147/57506 11 Varicella.zoster_virus R-HSA-73933 Resolution of Abasic Sites (AP sites) 27/4500 39/10654 5.904609100210062e-4 0.001162600042862235 4.646192299177987e-4 2237/4913/5982/6117/10714/6118/328/3978/5985/5984/4595/5424/7515/54107/5425/5111/6119/5427/142/4968/3980/5983/56655/57804/6996/5426/5981 27 Varicella.zoster_virus R-HSA-429947 Deadenylation of mRNA 19/4500 25/10654 6.340442107639301e-4 0.001246655941164009 4.982111663526805e-4 26986/25904/1973/55571/57472/85456/29883/1981/1977/9924/4850/246175/4848/23019/1975/1974/4849/9337/9775 19 Varicella.zoster_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 16/4500 20/10654 6.543517924035527e-4 0.001284775108572939 5.134450366035725e-4 7321/7334/3551/7314/8737/8517/7323/6233/330/7098/7189/7311/1147/7316/7322/329 16 Varicella.zoster_virus R-HSA-112043 PLC beta mediated events 35/4500 54/10654 6.648780057759654e-4 0.0013036091236843365 5.209718259332668e-4 5331/2770/817/5578/814/2773/818/5567/5594/112/5573/2771/5580/5153/115/801/805/3838/5568/10645/5566/84254/23236/816/5577/815/5321/5575/114/2779/10768/5576/1385/808/5137 35 Varicella.zoster_virus R-HSA-8852135 Protein ubiquitination 48/4500 79/10654 6.68111536957676e-4 0.0013081117890503726 5.227712624013705e-4 11065/7321/56852/8239/56254/3093/7347/7328/5192/7334/7332/80349/7314/90268/79139/7323/29089/7324/6233/23168/7874/5193/123169/9646/79577/5591/7317/5111/9810/118424/5830/7327/7311/5195/9781/3105/997/7319/7320/7336/7316/54926/7415/7322/54623/5828/27338/5194 48 Varicella.zoster_virus R-HSA-114608 Platelet degranulation 73/4500 129/10654 6.696784604956318e-4 0.001309343320520871 5.232634292535528e-4 7042/5175/3082/7423/3920/374354/2244/3309/3690/87/10487/7040/5874/54863/350/7043/5054/5099/1072/7018/813/7094/7414/10490/7273/22927/1191/27154/226/2335/5478/94121/2266/5154/7076/2243/801/805/351/135228/7424/2316/3674/7277/334/10447/335/51706/308/197/81/9948/3481/54495/8407/7450/29789/10916/7422/1950/5216/6647/1893/7078/2/948/88/3479/5155/51368/808/213/7057 73 Varicella.zoster_virus R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission 110/4500 206/10654 7.297466052929954e-4 0.001424791973411219 5.694011053445529e-4 5563/4893/5579/5331/23426/2900/2770/51807/817/5578/347688/53632/10381/9463/7846/9495/2782/1134/1741/1739/163/6196/1740/8874/6197/8825/3845/3265/814/2773/5879/2787/5923/818/161/5567/4646/5594/51422/112/5573/2902/2901/3359/6714/2567/6195/2783/2784/2906/2771/115/1175/801/2891/4747/805/5170/1173/84617/3838/8573/2904/2890/10382/2556/5568/2036/7277/160/80852/10645/55327/5566/84254/2905/5571/27330/23236/3084/816/5577/10369/5562/10383/84790/5564/5565/5924/7280/5595/64130/815/28964/5575/59345/114/55970/5576/2903/4137/2066/4905/9647/1742/88/1385/808/8536/4193 110 Varicella.zoster_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 24/4500 34/10654 7.675519957950619e-4 0.0014965119918015453 5.980631546183223e-4 7321/3093/64135/83737/1540/7314/29110/9636/7323/23586/7128/3661/51191/6233/55593/7706/9246/7311/5094/57506/7316/7322/54941/5300 24 Varicella.zoster_virus R-HSA-1368108 BMAL1:CLOCK,NPAS2 activates circadian gene expression 20/4500 27/10654 7.985248463475008e-4 0.001552563628831631 6.204635223049046e-4 79718/28999/5469/1387/6907/10499/23054/85441/96764/5054/5465/6604/80205/406/8553/4862/6256/10498/8648/551 20 Varicella.zoster_virus R-HSA-3000170 Syndecan interactions 20/4500 27/10654 7.985248463475008e-4 0.001552563628831631 6.204635223049046e-4 5578/3688/3690/87/6382/7040/3655/2247/2335/3685/9672/3691/8573/1277/3371/6383/1281/3673/7057/1278 20 Varicella.zoster_virus R-HSA-196299 Beta-catenin phosphorylation cascade 14/4500 17/10654 8.672190850725814e-4 0.0016837800316569173 6.729025914478708e-4 5526/1452/8312/5518/5515/5528/5519/2932/10023/5529/5516/1499/5525/5527 14 Varicella.zoster_virus R-HSA-6798695 Neutrophil degranulation 236/4500 480/10654 0.0010244012497458794 0.0019862002008961773 7.93761202288474e-4 5869/8773/1727/5689/8804/5777/5806/4893/9218/4790/5273/960/1823/57826/1915/3107/203068/5175/383/654364/2268/5211/5908/1460/6280/5788/535/10312/5709/10576/1509/5695/2896/8655/567/7133/3106/3417/3043/388698/1667/2548/1432/11010/3920/5476/5683/3482/4311/2444/5702/566/9961/51552/10075/10487/684/6709/6093/8826/9522/4282/3608/2720/3312/387263/4758/1654/5879/51316/5718/1992/3303/58485/2934/161/56888/3579/5707/3848/823/427/5594/4831/5787/6727/7414/10533/4257/847/25852/3934/5834/1315/102/4069/965/4973/9861/5870/226/2821/978/55832/5713/2495/3728/5478/5719/5328/11001/5580/23191/3685/302/1729/64114/2040/230/317/23250/5663/7879/8907/10450/1828/23352/5284/83858/4332/10159/1938/1650/3684/79888/3163/3577/79169/5864/4318/3958/79980/23317/5836/6993/5329/966/1116/527/6279/6515/4048/353/6286/210/10092/5795/6793/197/140885/3310/1832/5708/3615/23218/820/51143/4860/6386/10788/6402/3326/10857/55004/10097/3916/10383/387/196527/79930/5049/51806/80184/3304/2547/8673/10493/22931/1778/10694/3837/10890/5036/8621/327/11333/5315/8876/23197/10120/7520/5717/2919/221/2357/10213/6278/932/9588/7415/3146/5701/6836/3320/5686/388697/5873/5878/2683/11031/22875/948/719/93100/47/5906/89777/3687/7097/2212/10970/3689/2207/5724/51382/2950 236 Varicella.zoster_virus R-HSA-1660499 Synthesis of PIPs at the plasma membrane 34/4500 53/10654 0.0010390625412303647 0.002011832604102065 8.040048862721268e-4 5295/5291/5783/5286/55300/8871/660/4534/51552/54477/5290/5868/59339/81846/146850/5294/8394/8898/8776/22874/8867/8503/55613/3636/59338/5867/5293/5305/64419/5287/5728/5296/375/4952 34 Varicella.zoster_virus R-HSA-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase 12/4500 14/10654 0.001087574932184252 0.002081755943289154 8.319489141481315e-4 5567/5573/801/805/5568/5566/5577/5575/114/5576/1385/808 12 Varicella.zoster_virus R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 12/4500 14/10654 0.001087574932184252 0.002081755943289154 8.319489141481315e-4 5526/1452/8312/5518/5515/5528/5519/2932/5529/5516/5525/5527 12 Varicella.zoster_virus R-HSA-4839744 truncated APC mutants destabilize the destruction complex 12/4500 14/10654 0.001087574932184252 0.002081755943289154 8.319489141481315e-4 5526/1452/8312/5518/5515/5528/5519/2932/5529/5516/5525/5527 12 Varicella.zoster_virus R-HSA-4839748 AMER1 mutants destabilize the destruction complex 12/4500 14/10654 0.001087574932184252 0.002081755943289154 8.319489141481315e-4 5526/1452/8312/5518/5515/5528/5519/2932/5529/5516/5525/5527 12 Varicella.zoster_virus R-HSA-5467337 APC truncation mutants have impaired AXIN binding 12/4500 14/10654 0.001087574932184252 0.002081755943289154 8.319489141481315e-4 5526/1452/8312/5518/5515/5528/5519/2932/5529/5516/5525/5527 12 Varicella.zoster_virus R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 12/4500 14/10654 0.001087574932184252 0.002081755943289154 8.319489141481315e-4 5526/1452/8312/5518/5515/5528/5519/2932/5529/5516/5525/5527 12 Varicella.zoster_virus R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 12/4500 14/10654 0.001087574932184252 0.002081755943289154 8.319489141481315e-4 5526/1452/8312/5518/5515/5528/5519/2932/5529/5516/5525/5527 12 Varicella.zoster_virus R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 12/4500 14/10654 0.001087574932184252 0.002081755943289154 8.319489141481315e-4 4893/2909/5753/9564/3845/3265/5829/5879/5921/387/63916/1398 12 Varicella.zoster_virus R-HSA-445355 Smooth Muscle Contraction 27/4500 40/10654 0.001088597305588168 0.002081755943289154 8.319489141481315e-4 140465/7169/5062/5829/4638/7094/7414/3672/859/800/302/801/805/10627/301/59/5058/4629/7170/72/7168/7171/10174/10398/4637/103910/808 27 Varicella.zoster_virus R-HSA-112040 G-protein mediated events 35/4500 55/10654 0.0010905376251548577 0.002082613576903121 8.3229165718493e-4 5331/2770/817/5578/814/2773/818/5567/5594/112/5573/2771/5580/5153/115/801/805/3838/5568/10645/5566/84254/23236/816/5577/815/5321/5575/114/2779/10768/5576/1385/808/5137 35 Varicella.zoster_virus R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 22/4500 31/10654 0.0011373145346017044 0.002168976899322376 8.668057281261193e-4 857/5526/1452/8312/1855/5518/5515/1856/7471/5528/89780/5519/2932/1857/4040/10023/5529/5516/1499/5525/1455/5527 22 Varicella.zoster_virus R-HSA-6783589 Interleukin-6 family signaling 18/4500 24/10654 0.0011577812237437766 0.0022049967098858284 8.812006154723942e-4 9021/3717/3569/3572/3976/3570/7297/5781/9180/3589/6774/6772/3716/1270/5008/867/3977/1489 18 Varicella.zoster_virus R-HSA-2025928 Calcineurin activates NFAT 10/4500 11/10654 0.0012184934280844628 0.0022986713859539324 9.186365816284004e-4 5530/4773/5478/801/805/4772/4775/5532/5534/808 10 Varicella.zoster_virus R-HSA-2468052 Establishment of Sister Chromatid Cohesion 10/4500 11/10654 0.0012184934280844628 0.0022986713859539324 9.186365816284004e-4 10274/157570/113130/23047/5885/8243/23244/10735/9126/114799 10 Varicella.zoster_virus R-HSA-3371378 Regulation by c-FLIP 10/4500 11/10654 0.0012184934280844628 0.0022986713859539324 9.186365816284004e-4 356/8737/841/8797/8772/8717/8837/8795/7186/355 10 Varicella.zoster_virus R-HSA-4755510 SUMOylation of immune response proteins 10/4500 11/10654 0.0012184934280844628 0.0022986713859539324 9.186365816284004e-4 4792/6612/51588/8517/5970/4791/10210/7329/7341/10401 10 Varicella.zoster_virus R-HSA-5218900 CASP8 activity is inhibited 10/4500 11/10654 0.0012184934280844628 0.0022986713859539324 9.186365816284004e-4 356/8737/841/8797/8772/8717/8837/8795/7186/355 10 Varicella.zoster_virus R-HSA-69416 Dimerization of procaspase-8 10/4500 11/10654 0.0012184934280844628 0.0022986713859539324 9.186365816284004e-4 356/8737/841/8797/8772/8717/8837/8795/7186/355 10 Varicella.zoster_virus R-HSA-9020956 Interleukin-27 signaling 10/4500 11/10654 0.0012184934280844628 0.0022986713859539324 9.186365816284004e-4 3717/3572/10148/7297/821/6774/6772/3716/246778/9466 10 Varicella.zoster_virus R-HSA-375165 NCAM signaling for neurite out-growth 39/4500 63/10654 0.0012596959329201792 0.002373192337863118 9.484179905500321e-4 2674/9252/4893/6711/5621/4684/2668/2534/779/2885/6709/3845/5623/3265/6900/7903/375790/5594/4902/2260/6714/64096/51332/6712/5747/2675/6710/775/782/6654/5595/5786/1299/776/57731/1281/6708/1385/9048 39 Varicella.zoster_virus R-HSA-202433 Generation of second messenger molecules 23/4500 33/10654 0.0013047913657731074 0.0024548365857402395 9.810461396790283e-4 5335/3115/3127/5062/916/3702/3932/3937/3123/3122/920/5063/7535/5058/55740/9402/4690/919/27040/915/917/7408/7454 23 Varicella.zoster_virus R-HSA-9612973 Autophagy 67/4500 119/10654 0.0013099793793571396 0.0024612802336239125 9.836212666420403e-4 5563/2670/65018/1459/1915/8878/1460/53632/5116/8655/1457/3043/3920/29082/55054/2475/84557/3312/11315/64121/7314/139341/9821/51422/7249/10533/10013/91782/192111/6714/89853/123/55669/6233/9804/57521/140735/79643/7416/26100/64223/5571/128866/3326/55004/7311/5562/93343/11345/55626/7251/5564/5565/7248/11337/1080/64419/7316/8678/56993/3320/81631/10542/23710/54543/200894/7431 67 Varicella.zoster_virus R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 19/4500 26/10654 0.0014227856903332012 0.002669635515732727 0.0010668879681332722 83990/9156/1763/7486/472/4683/672/5888/116028/80010/580/641/10524/79728/10111/675/10635/5932/7156 19 Varicella.zoster_virus R-HSA-390466 Chaperonin-mediated protein folding 55/4500 95/10654 0.001451856228166853 0.0027205252275448685 0.0010872254340210982 9134/1459/2770/51807/10528/1460/10381/10576/1457/7846/7411/2782/10574/10693/8877/2773/5201/2787/5204/10575/898/10471/26985/2783/2784/10238/7157/2771/83752/5202/84617/8237/10382/7277/6774/26272/26270/55135/10383/60/84790/22948/7280/10694/8841/22803/59345/5203/2779/7203/908/55970/6950/55294/6499 55 Varicella.zoster_virus R-HSA-432720 Lysosome Vesicle Biogenesis 24/4500 35/10654 0.0014675819771280281 0.002746306219933951 0.0010975284998982007 8906/162/1212/1174/1785/11154/408/6456/3312/10053/9146/4074/6844/1213/1211/8907/351/9829/8905/8673/164/1777/6845/375 24 Varicella.zoster_virus R-HSA-9008059 Interleukin-37 signaling 16/4500 21/10654 0.0016685675249165078 0.00311823328618935 0.0012461647124719921 834/5777/26469/5783/27178/59307/4088/29110/8809/5781/5782/6774/5771/5778/25930/5784 16 Varicella.zoster_virus R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 26/4500 39/10654 0.0017723379415242426 0.003307732307978399 0.001321895734601532 9134/10528/10576/10574/10693/8877/10575/898/26985/10238/7157/83752/8237/6774/26272/26270/55135/22948/10694/8841/22803/7203/908/6950/55294/6499 26 Varicella.zoster_virus R-HSA-186797 Signaling by PDGF 36/4500 58/10654 0.001790484519558344 0.003337138036453202 0.00133364738298914 5295/4893/5335/5291/6696/6776/2885/8440/9564/3845/3265/1399/56034/5290/5921/6778/6714/5154/6777/5781/80310/5782/6774/6772/2889/5159/2886/6654/4690/1299/1281/1398/5155/5296/7057/5156 36 Varicella.zoster_virus R-HSA-5140745 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 11/4500 13/10654 0.0022302274064183304 0.0041401561959574324 0.00165456400532155 1212/163/4920/161/7474/1213/1211/1175/1173/160/4919 11 Varicella.zoster_virus R-HSA-68884 Mitotic Telophase/Cytokinesis 11/4500 13/10654 0.0022302274064183304 0.0041401561959574324 0.00165456400532155 10274/10112/9493/25836/23047/5885/8243/5347/23244/10735/9126 11 Varicella.zoster_virus R-HSA-879415 Advanced glycosylation endproduct receptor signaling 11/4500 13/10654 0.0022302274064183304 0.0041401561959574324 0.00165456400532155 177/5594/351/1650/830/3958/829/5595/3146/6288/6285 11 Varicella.zoster_virus R-HSA-4791275 Signaling by WNT in cancer 23/4500 34/10654 0.0024281100484544607 0.004501516105766835 0.0017989771799550769 27123/5526/1452/8312/79412/5518/5515/8322/5528/89780/5519/2932/4040/6934/5529/5516/1487/1499/5525/27121/54894/5527/1488 23 Varicella.zoster_virus R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 18/4500 25/10654 0.0025045335428348233 0.004630899107016442 0.001850683552042463 51807/10381/10576/7846/10574/10693/10575/84617/10382/7277/10383/84790/22948/7280/10694/7203/908/6950 18 Varicella.zoster_virus R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 18/4500 25/10654 0.0025045335428348233 0.004630899107016442 0.001850683552042463 3107/10484/811/567/3106/3309/3133/22872/10134/6396/3135/10802/6890/821/2923/9871/3105/3134 18 Varicella.zoster_virus R-HSA-8875656 MET receptor recycling 9/4500 10/10654 0.002641751313803226 0.004878154542419713 0.0019494962354716094 3082/2885/1399/382/4233/5867/2549/1398/23163 9 Variola_virus R-HSA-449147 Signaling by Interleukins 111/346 461/10654 1.2296032760254095e-68 1.1988631941247742e-65 7.054039846672085e-66 149233/8454/6500/3605/7124/2353/5743/604/282618/3594/53832/7132/1154/10148/1432/3725/7291/6347/3932/9655/3558/4067/3717/11009/2208/3592/598/1438/5290/836/6778/53833/4615/3581/7040/3687/3566/1437/5698/3588/51561/4843/3570/8835/5599/2534/3597/6776/5600/6597/3688/6777/5008/3565/9978/3312/3561/9466/3559/3560/3587/5771/246778/55801/6773/6352/7412/3458/3578/50615/7184/7297/5781/5702/6774/3569/7157/5970/4792/5062/3593/3689/6775/207/5696/50616/3684/3718/3627/3586/3654/9021/7422/7133/29110/3553/163702/6772/2625/1439/5594/8651/4609/3572/3595/3596/7525/5595/58985/59067/3716 111 Variola_virus R-HSA-913531 Interferon Signaling 63/346 199/10654 7.012062650455574e-46 3.4183805420970926e-43 2.011354812893836e-43 3459/3665/818/3460/4939/9636/815/2537/5610/11274/8638/3717/25820/7706/10379/2634/3127/5335/4940/91543/3437/115362/3455/5771/3394/3456/6773/7412/3458/4938/3454/7297/816/5781/4261/3430/3661/817/2633/10346/7324/5696/3836/9021/9246/3660/3434/5371/3439/54739/6772/8651/51191/3659/3433/4600/4599/5595/3106/8554/5580/3716/23586 63 Variola_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 48/346 108/10654 3.1232128387372184e-43 1.015044172589596e-40 5.972459638988716e-41 149233/3605/7124/2353/5743/604/7291/6347/9655/3717/2208/3592/598/6778/7040/3687/3566/51561/4843/3570/3597/3688/5008/3565/3312/3561/7412/7184/7297/6774/3569/7157/3593/3689/207/3684/3718/3586/9021/7422/7133/3553/6772/2625/8651/4609/3596/3716 48 Variola_virus R-HSA-909733 Interferon alpha/beta signaling 35/346 69/10654 3.005392852794317e-34 7.325645078686147e-32 4.310366065191849e-32 3665/4939/9636/2537/11274/8638/10379/2634/4940/91543/3437/3455/3394/3456/6773/4938/3454/7297/5781/3430/3661/5696/9021/3660/3434/3439/54739/6772/8651/3659/3433/4600/4599/3106/3716 35 Variola_virus R-HSA-5663202 Diseases of signal transduction 68/346 377/10654 1.7633077362056973e-32 3.43845008560111e-30 2.0231636131202212e-30 2475/8454/6500/409/84441/7048/818/399687/2932/10533/2261/1387/3932/815/2931/2064/5159/5155/8805/3717/11052/1956/26127/8841/5290/10046/7040/5698/9208/5335/2534/2033/6776/2100/6777/1499/55294/9978/1950/3516/3815/816/5781/5702/3065/6774/2263/23462/9759/817/207/5696/7750/1452/6772/55534/6714/2099/5594/3280/5156/9794/4609/1523/7415/613/5595/64223 68 Variola_virus R-HSA-877300 Interferon gamma signaling 36/346 92/10654 3.915908618609094e-30 6.363351505239777e-28 3.744158240599923e-28 3459/3665/818/3460/4939/815/8638/3717/7706/10379/2634/3127/4940/115362/5771/3394/7412/3458/4938/816/5781/4261/3661/817/2633/10346/9021/3660/5371/6772/8651/3659/3106/8554/5580/3716 36 Variola_virus R-HSA-8854691 Interleukin-20 family signaling 20/346 25/10654 4.5385309567169456e-26 6.3215252611414596e-24 3.719547926933437e-24 282618/53832/3717/11009/53833/3588/6776/6777/55801/6773/7297/5781/6774/6775/50616/3718/163702/6772/58985/3716 20 Variola_virus R-HSA-982772 Growth hormone receptor signaling 18/346 24/10654 1.1770200431136873e-22 1.4344931775448063e-20 8.440472677591572e-21 1154/5617/4067/3717/5618/8835/6776/6777/2690/2689/6774/9021/2688/6772/5594/8651/1442/5595 18 Variola_virus R-HSA-8878166 Transcriptional regulation by RUNX2 33/346 121/10654 6.4201557600303e-22 6.955168740032824e-20 4.0923799873877357e-20 8454/6500/57154/7291/2932/860/1750/6502/8841/2908/5698/2101/1749/55294/4488/9978/865/5702/133522/23462/9759/207/5696/10413/579/6772/6714/2099/5594/3280/10891/7525/5595 33 Variola_virus R-HSA-451927 Interleukin-2 family signaling 21/346 44/10654 3.0927800804135786e-20 3.015460578403239e-18 1.7742790987635793e-18 3932/3558/3717/1438/5290/3581/1437/6776/6777/3561/3559/3560/3578/50615/6774/6775/3718/6772/1439/59067/3716 21 Variola_virus R-HSA-5683057 MAPK family signaling cascades 46/346 294/10654 2.238387150086147e-19 1.9840249739399942e-17 1.1673885136812922e-17 6710/409/7514/818/3725/2261/815/2064/5159/5155/3558/3717/1956/6711/1438/1437/5698/3570/2534/1844/9978/3561/1950/3559/3560/5747/3815/7297/816/5781/5702/3569/2263/5062/817/5696/3718/1439/6714/5594/5156/4609/3572/5595/6709/3716 46 Variola_virus R-HSA-5684996 MAPK1/MAPK3 signaling 42/346 255/10654 1.3226535883061768e-18 1.0746560404987686e-16 6.32321233006023e-17 6710/409/818/2261/815/2064/5159/5155/3558/3717/1956/6711/1438/1437/5698/3570/2534/1844/9978/3561/1950/3559/3560/5747/3815/7297/816/5781/5702/3569/2263/817/5696/3718/1439/6714/5594/5156/3572/5595/6709/3716 42 Variola_virus R-HSA-1170546 Prolactin receptor signaling 13/346 15/10654 3.547936644109789e-18 2.660952483082342e-16 1.565688640518085e-16 8454/6500/5617/3717/5618/6776/6777/9978/2690/2689/5781/2688/1442 13 Variola_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 23/346 73/10654 3.665420581394567e-17 2.552703619185502e-15 1.5019956517744654e-15 8454/6500/57154/7291/2932/860/1750/6502/2908/5698/2101/1749/55294/4488/9978/865/5702/133522/5696/579/6772/2099/10891 23 Variola_virus R-HSA-9607240 FLT3 Signaling 41/346 267/10654 4.728437029170381e-17 3.0734840689607476e-15 1.808419776068672e-15 6710/409/818/2261/815/2064/5159/5155/3558/3717/1956/6711/1438/5290/1437/5698/2534/6776/1844/6777/9978/3561/1950/3559/3560/5747/3815/816/5781/5702/2263/817/5696/3718/1439/6714/5594/5156/5595/6709/3716 41 Variola_virus R-HSA-6783783 Interleukin-10 signaling 19/346 47/10654 9.794679986554744e-17 5.968633116806797e-15 3.511908284652852e-15 7124/5743/7132/6347/2208/3592/1437/3588/3587/6352/7297/6774/3569/3593/3627/3586/7133/3553/3716 19 Variola_virus R-HSA-9006925 Intracellular signaling by second messengers 43/346 305/10654 1.958507629969524e-16 1.1232617289531094e-14 6.609205314757836e-15 2475/818/3725/2932/2261/3932/815/2931/2064/5159/5155/1956/8841/5290/5581/4615/5698/5335/2534/2100/5468/1950/3815/816/5781/3630/5702/3065/2263/7157/817/207/8975/5696/3654/5371/6714/2099/5594/5156/5595/5580/64223 43 Variola_virus R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 13/346 18/10654 2.650041338838484e-16 1.435439058537512e-14 8.446038185186983e-15 399687/8805/11052/26127/5290/9208/6776/6777/6774/7750/6772/1523/613 13 Variola_virus R-HSA-8984722 Interleukin-35 Signalling 11/346 12/10654 4.228263377918082e-16 2.1697667334053316e-14 1.2766778620306674e-14 10148/3717/3592/9466/7297/6774/6775/6772/3572/3595/3716 11 Variola_virus R-HSA-9020958 Interleukin-21 signaling 10/346 10/10654 1.149374180802682e-15 5.6031991314130746e-14 3.296889097565588e-14 6776/6777/3561/50615/6774/6775/3718/6772/59067/3716 10 Variola_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 22/346 80/10654 4.514959158615928e-15 2.096231037928824e-13 1.233409895461494e-13 4939/9636/5610/11274/8638/25820/7706/5335/4940/4938/3661/7324/3836/9246/3434/6772/51191/4600/4599/5595/3716/23586 22 Variola_virus R-HSA-5673001 RAF/MAP kinase cascade 37/346 249/10654 5.238699438203749e-15 2.3216963419312073e-13 1.3660723415411693e-13 6710/409/818/2261/815/2064/5159/5155/3558/3717/1956/6711/1438/1437/5698/2534/1844/9978/3561/1950/3559/3560/5747/3815/816/5702/2263/817/5696/3718/1439/6714/5594/5156/5595/6709/3716 37 Variola_virus R-HSA-447115 Interleukin-12 family signaling 19/346 57/10654 6.6511199697905976e-15 2.819496508932971e-13 1.6589750039065793e-13 149233/3594/10148/3717/3592/51561/9466/246778/3458/7297/6774/5062/3593/6775/3586/6772/3572/3595/3716 19 Variola_virus R-HSA-877312 Regulation of IFNG signaling 11/346 14/10654 1.2096416962813734e-14 4.789313927251583e-13 2.8180038762236037e-13 3459/3460/3717/5771/3458/5781/9021/6772/8651/8554/3716 11 Variola_virus R-HSA-1059683 Interleukin-6 signaling 10/346 11/10654 1.2280292121157904e-14 4.789313927251583e-13 2.8180038762236037e-13 3717/3570/7297/5781/6774/3569/9021/6772/3572/3716 10 Variola_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 21/346 78/10654 3.068092035771639e-14 1.1505345134143647e-12 6.769676759091269e-13 7128/3665/9636/1387/7706/8772/7186/2033/64135/1540/3456/8737/5970/4792/3661/9246/29110/3439/57506/51191/23586 21 Variola_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 17/346 47/10654 3.8050271622882546e-14 1.3740375863818698e-12 8.084755568994538e-13 8454/6500/84441/1387/8841/10046/2033/55294/9978/3516/3065/23462/9759/55534/3280/9794/4609 17 Variola_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 17/346 48/10654 5.71959612910228e-14 1.991645080669544e-12 1.1718721392333618e-12 3558/4067/3717/1438/5290/1437/2534/6776/6777/3561/3559/3560/5781/3718/1439/7525/3716 17 Variola_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 50/346 473/10654 8.305052009518154e-14 2.7922157618207587e-12 1.6429231742966948e-12 2475/3685/1432/2261/3932/2064/5159/5155/4067/3717/1956/5290/4914/6778/5581/2670/5335/2534/6776/5600/9306/3688/6777/1499/1950/5747/5771/6300/528/3815/5603/5781/3630/6774/2263/5062/207/10413/7422/6772/6714/2099/5594/8651/5156/7525/5595/6387/5580/64223 50 Variola_virus R-HSA-4090294 SUMOylation of intracellular receptors 14/346 30/10654 1.0167121742088457e-13 3.3043145661787483e-12 1.944239069978319e-12 9063/10401/2908/5465/5468/9759/7421/6256/7329/7376/2099/51588/10062/8554 14 Variola_virus R-HSA-1257604 PIP3 activates AKT signaling 36/346 264/10654 1.8529268147060483e-13 5.827753691414184e-12 3.4290156672828397e-12 2475/3725/2932/2261/3932/2931/2064/5159/5155/1956/8841/5290/4615/5698/2534/2100/5468/1950/3815/5781/3630/5702/3065/2263/7157/207/8975/5696/3654/5371/6714/2099/5594/5156/5595/64223 36 Variola_virus R-HSA-918233 TRAF3-dependent IRF activation pathway 10/346 14/10654 1.024061921907745e-12 3.12018866831266e-11 1.835900484999082e-11 3665/1387/7706/2033/64135/3456/3661/29110/57506/23586 10 Variola_virus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 22/346 103/10654 1.281095886666499e-12 3.785056028787383e-11 2.2271044919720635e-11 2261/3932/2064/5159/5155/1956/5290/4615/2534/2100/1950/3815/5781/3630/2263/207/3654/6714/2099/5594/5156/5595 22 Variola_virus R-HSA-9020956 Interleukin-27 signaling 9/346 11/10654 1.884669139782355e-12 4.9482561674820424e-11 2.911524546588624e-11 10148/3717/9466/246778/7297/6774/6772/3572/3716 9 Variola_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 17/346 58/10654 1.979302466992817e-12 4.9482561674820424e-11 2.911524546588624e-11 8454/6500/84441/1387/8841/10046/2033/55294/9978/3516/3065/23462/9759/55534/3280/9794/4609 17 Variola_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 17/346 58/10654 1.979302466992817e-12 4.9482561674820424e-11 2.911524546588624e-11 8454/6500/84441/1387/8841/10046/2033/55294/9978/3516/3065/23462/9759/55534/3280/9794/4609 17 Variola_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 17/346 58/10654 1.979302466992817e-12 4.9482561674820424e-11 2.911524546588624e-11 8454/6500/84441/1387/8841/10046/2033/55294/9978/3516/3065/23462/9759/55534/3280/9794/4609 17 Variola_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 17/346 58/10654 1.979302466992817e-12 4.9482561674820424e-11 2.911524546588624e-11 8454/6500/84441/1387/8841/10046/2033/55294/9978/3516/3065/23462/9759/55534/3280/9794/4609 17 Variola_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 17/346 58/10654 1.979302466992817e-12 4.9482561674820424e-11 2.911524546588624e-11 8454/6500/84441/1387/8841/10046/2033/55294/9978/3516/3065/23462/9759/55534/3280/9794/4609 17 Variola_virus R-HSA-1433557 Signaling by SCF-KIT 15/346 43/10654 2.316163303141744e-12 5.645648051408001e-11 3.321865790032238e-11 3932/4067/3717/5290/2534/6776/9306/6777/3815/5781/6774/6772/6714/8651/7525 15 Variola_virus R-HSA-168898 Toll-like Receptor Cascades 26/346 155/10654 4.170707443353975e-12 9.918145749439331e-11 5.835778065796962e-11 8454/6500/2353/3665/1432/3725/8772/4615/7098/5599/5600/7097/7184/5781/8737/5970/4792/3661/3689/3684/3654/29110/5594/8651/5595/51311 26 Variola_virus R-HSA-1839124 FGFR1 mutant receptor activation 13/346 31/10654 4.349214562086612e-12 1.0096390947701063e-10 5.940656482048129e-11 399687/8805/11052/26127/5290/9208/6776/6777/6774/7750/6772/1523/613 13 Variola_virus R-HSA-199418 Negative regulation of the PI3K/AKT network 22/346 110/10654 5.218083352102258e-12 1.1828828551456877e-10 6.960012481019161e-11 2261/3932/2064/5159/5155/1956/5290/4615/2534/2100/1950/3815/5781/3630/2263/207/3654/6714/2099/5594/5156/5595 22 Variola_virus R-HSA-5655302 Signaling by FGFR1 in disease 14/346 38/10654 5.338138012965154e-12 1.1828828551456877e-10 6.960012481019161e-11 399687/8805/11052/26127/5290/9208/5335/6776/6777/6774/7750/6772/1523/613 14 Variola_virus R-HSA-912694 Regulation of IFNA signaling 12/346 26/10654 7.309914568878471e-12 1.5193349688542717e-10 8.939676739817307e-11 11274/3455/3456/6773/3454/7297/5781/9021/3439/6772/8651/3716 12 Variola_virus R-HSA-2219528 PI3K/AKT Signaling in Cancer 21/346 101/10654 7.31125786419634e-12 1.5193349688542717e-10 8.939676739817307e-11 2475/2932/2261/3932/2931/2064/5159/5155/1956/5290/2534/2100/1950/3815/5781/2263/207/6714/2099/5156/64223 21 Variola_virus R-HSA-9020558 Interleukin-2 signaling 9/346 12/10654 7.323973696015463e-12 1.5193349688542717e-10 8.939676739817307e-11 3932/3558/6776/6777/3561/3559/3560/3718/3716 9 Variola_virus R-HSA-1169408 ISG15 antiviral mechanism 18/346 72/10654 8.729037312055594e-12 1.7730857040112924e-10 1.0432730997961182e-10 9636/5610/11274/25820/7706/5335/3661/7324/3836/9246/3434/6772/51191/4600/4599/5595/3716/23586 18 Variola_virus R-HSA-1980143 Signaling by NOTCH1 18/346 73/10654 1.1247357146160397e-11 2.2379945341849766e-10 1.31682269487807e-10 8454/6500/409/84441/1387/8841/10046/2033/55294/9978/3516/3065/23462/9759/55534/3280/9794/4609 18 Variola_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 23/346 129/10654 2.0599416353511675e-11 4.0168861889347764e-10 2.363511981613445e-10 8454/6500/2353/3665/1432/3725/8772/4615/5599/5600/7097/5781/8737/5970/4792/3661/3689/3684/3654/29110/5594/8651/5595 23 Variola_virus R-HSA-8878159 Transcriptional regulation by RUNX3 20/346 96/10654 2.249659513847879e-11 4.300819658826827e-10 2.530576749323208e-10 84441/57154/1387/10046/7040/5698/2033/1499/865/3516/5702/7157/9759/5696/10413/55534/6714/3280/9794/4609 20 Variola_virus R-HSA-5357786 TNFR1-induced proapoptotic signaling 9/346 13/10654 2.312514832070517e-11 4.3359653101322194e-10 2.5512562418591736e-10 7124/7128/7132/9099/8772/7186/8717/1540/8737 9 Variola_virus R-HSA-186763 Downstream signal transduction 12/346 29/10654 3.596868390729863e-11 6.494345705484475e-10 3.8212344501905955e-10 5159/5155/5290/6778/5335/6776/6777/5781/6774/6772/6714/5156 12 Variola_virus R-HSA-933541 TRAF6 mediated IRF7 activation 12/346 29/10654 3.596868390729863e-11 6.494345705484475e-10 3.8212344501905955e-10 3665/1387/7706/7186/2033/64135/3456/3661/29110/3439/57506/23586 12 Variola_virus R-HSA-110056 MAPK3 (ERK1) activation 8/346 10/10654 4.859568451793371e-11 8.614689528179157e-10 5.068832165028492e-10 3717/3570/7297/5781/3569/3572/5595/3716 8 Variola_virus R-HSA-3371571 HSF1-dependent transactivation 11/346 24/10654 6.191487733345938e-11 1.0590702701775948e-9 6.231506582961286e-10 2475/818/1387/815/2033/3312/816/3297/817/3326/64223 11 Variola_virus R-HSA-6783589 Interleukin-6 family signaling 11/346 24/10654 6.191487733345938e-11 1.0590702701775948e-9 6.231506582961286e-10 3717/3570/5008/7297/5781/6774/3569/9021/6772/3572/3716 11 Variola_virus R-HSA-1226099 Signaling by FGFR in disease 16/346 63/10654 9.917819949232358e-11 1.6672197328450945e-9 9.809821909857777e-10 399687/2261/8805/11052/26127/5290/9208/5335/6776/6777/6774/2263/7750/6772/1523/613 16 Variola_virus R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 11/346 25/10654 1.073774720701774e-10 1.774458224888525e-9 1.0440806829303602e-9 84441/1387/10046/2033/4854/3516/23462/6772/55534/3280/9794 11 Variola_virus R-HSA-157118 Signaling by NOTCH 30/346 235/10654 1.1366953481385428e-10 1.847129940725132e-9 1.0868402890096595e-9 8454/6500/409/84441/3725/1387/1956/8841/2208/10046/5698/2033/55294/9978/1869/1950/4854/3516/5702/3065/7157/23462/9759/207/5696/6772/55534/3280/9794/4609 30 Variola_virus R-HSA-912526 Interleukin receptor SHC signaling 11/346 27/10654 2.9624878833970285e-10 4.73512407592148e-9 2.786118889476066e-9 3558/3717/1438/5290/1437/3561/3559/3560/3718/1439/3716 11 Variola_virus R-HSA-210990 PECAM1 interactions 8/346 12/10654 5.0482722918698e-10 7.812802356465167e-9 4.597006514735239e-9 3685/3932/4067/5335/2534/5781/6714/7525 8 Variola_virus R-HSA-2197563 NOTCH2 intracellular domain regulates transcription 8/346 12/10654 5.0482722918698e-10 7.812802356465167e-9 4.597006514735239e-9 84441/2208/10046/2033/3516/55534/3280/9794 8 Variola_virus R-HSA-9013694 Signaling by NOTCH4 17/346 82/10654 7.973792642860283e-10 1.2147574729357463e-8 7.14756083940601e-9 8454/6500/84441/1387/10046/5698/2033/55294/9978/3516/5702/23462/207/5696/55534/3280/9794 17 Variola_virus R-HSA-112409 RAF-independent MAPK1/3 activation 10/346 23/10654 9.009207489503234e-10 1.3492240059877105e-8 7.938753935366286e-9 3717/3570/1844/7297/5781/3569/5594/3572/5595/3716 10 Variola_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 25/346 182/10654 9.133208655916809e-10 1.3492240059877105e-8 7.938753935366286e-9 672/10155/1387/9063/10401/2908/5465/2033/5468/3065/7157/5970/4792/9759/7421/6256/7329/5371/7376/2099/4152/51588/10891/10062/8554 25 Variola_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 18/346 94/10654 9.885580661048866e-10 1.4385733051526334e-8 8.464479906161245e-9 8454/6500/2353/3665/1432/3725/8772/7098/5599/5600/8737/5970/4792/3661/3654/29110/5594/5595 18 Variola_virus R-HSA-8940973 RUNX2 regulates osteoblast differentiation 10/346 24/10654 1.5002106572480836e-9 2.1510373394365903e-8 1.2656575978331356e-8 860/8841/865/23462/10413/6714/5594/3280/7525/5595 10 Variola_virus R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 16/346 75/10654 1.622642555953265e-9 2.292864481238309e-8 1.3491078459108002e-8 2261/3932/2064/5159/5155/1956/5290/2534/2100/1950/3815/5781/2263/6714/2099/5156 16 Variola_virus R-HSA-2990846 SUMOylation 25/346 188/10654 1.822338605616874e-9 2.5382573435377886e-8 1.493495548964205e-8 672/10155/1387/9063/10401/2908/5465/2033/5468/3065/7157/5970/4792/9759/7421/6256/7329/5371/7376/2099/4152/51588/10891/10062/8554 25 Variola_virus R-HSA-166166 MyD88-independent TLR4 cascade 18/346 99/10654 2.379488768604411e-9 3.222224374151807e-8 1.8959376884348013e-8 8454/6500/2353/3665/1432/3725/8772/5599/5600/5781/8737/5970/4792/3661/3654/29110/5594/5595 18 Variola_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 18/346 99/10654 2.379488768604411e-9 3.222224374151807e-8 1.8959376884348013e-8 8454/6500/2353/3665/1432/3725/8772/5599/5600/5781/8737/5970/4792/3661/3654/29110/5594/5595 18 Variola_virus R-HSA-8941326 RUNX2 regulates bone development 11/346 32/10654 2.533353366368131e-9 3.383588400286202e-8 1.9908833232453227e-8 860/8841/865/23462/9759/10413/6714/5594/3280/7525/5595 11 Variola_virus R-HSA-8941856 RUNX3 regulates NOTCH signaling 8/346 14/10654 2.8924084982189903e-9 3.810943629410156e-8 2.2423366024599566e-8 84441/1387/10046/2033/3516/55534/3280/9794 8 Variola_virus R-HSA-109581 Apoptosis 24/346 178/10654 2.93228154052526e-9 3.811966002682838e-8 2.24293816082283e-8 840/999/598/8772/836/5698/7186/5599/8717/1499/1869/5747/5702/8737/6774/7157/5062/207/5696/3836/5594/5595/5580/6709 24 Variola_virus R-HSA-3371556 Cellular response to heat stress 17/346 89/10654 3.031327645854563e-9 3.8888742825107885e-8 2.2881905359982506e-8 2475/818/2932/1387/815/2033/3312/6767/816/3297/817/22824/5594/7415/5595/3326/64223 17 Variola_virus R-HSA-9012852 Signaling by NOTCH3 13/346 49/10654 3.260111557865408e-9 4.128063336258147e-8 2.4289279549373168e-8 84441/1387/1956/10046/2033/1950/4854/3516/23462/6772/55534/3280/9794 13 Variola_virus R-HSA-450341 Activation of the AP-1 family of transcription factors 7/346 10/10654 3.959644240545818e-9 4.9495553006822726e-8 2.9122889488494882e-8 2353/1432/3725/5599/5600/5594/5595 7 Variola_virus R-HSA-5357801 Programmed Cell Death 24/346 181/10654 4.12108233354214e-9 5.086145917979223e-8 2.99265805700262e-8 840/999/598/8772/836/5698/7186/5599/8717/1499/1869/5747/5702/8737/6774/7157/5062/207/5696/3836/5594/5595/5580/6709 24 Variola_virus R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 9/346 20/10654 4.438568351984987e-9 5.4095051789817025e-8 3.1829207260944973e-8 84441/1387/10046/2033/3516/23462/55534/3280/9794 9 Variola_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 11/346 34/10654 5.298835990859304e-9 6.378228507515829e-8 3.7529117804006776e-8 7128/9636/7706/64135/1540/3661/9246/29110/57506/51191/23586 11 Variola_virus R-HSA-350054 Notch-HLH transcription pathway 10/346 28/10654 8.937317105807395e-9 1.0626688022149036e-7 6.252680131790795e-8 84441/1387/8841/10046/4854/3516/3065/9759/55534/9794 10 Variola_virus R-HSA-1433559 Regulation of KIT signaling 8/346 16/10654 1.1707498111059842e-8 1.3589060307480174e-7 7.995722394144879e-8 3932/4067/2534/9306/3815/6714/8651/7525 8 Variola_virus R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 8/346 16/10654 1.1707498111059842e-8 1.3589060307480174e-7 7.995722394144879e-8 84441/1387/10046/2033/3516/55534/3280/9794 8 Variola_virus R-HSA-4420097 VEGFA-VEGFR2 Pathway 17/346 99/10654 1.641822500630961e-8 1.8832669860178669e-7 1.1081031118809582e-7 2475/3685/1432/5290/5335/2534/5600/1499/5747/6300/5603/5062/207/7422/6714/5580/64223 17 Variola_virus R-HSA-194138 Signaling by VEGF 17/346 107/10654 5.4481574993760614e-8 6.110498108360967e-7 3.5953808033001094e-7 2475/3685/1432/5290/5335/2534/5600/1499/5747/6300/5603/5062/207/7422/6714/5580/64223 17 Variola_virus R-HSA-389356 CD28 co-stimulation 10/346 33/10654 5.452444465922093e-8 6.110498108360967e-7 3.5953808033001094e-7 2475/3932/4067/5290/2534/5062/207/6714/7525/64223 10 Variola_virus R-HSA-8878171 Transcriptional regulation by RUNX1 26/346 239/10654 6.045718000651165e-8 6.698380739357825e-7 3.941287452577613e-7 6595/4005/860/1387/3558/1437/5698/10138/2033/6597/50943/3276/3559/865/3458/5781/5702/3065/5696/9021/10413/5371/2625/6714/2099/122809 26 Variola_virus R-HSA-186712 Regulation of beta-cell development 11/346 42/10654 6.277842937371597e-8 6.877412206671132e-7 4.046628504869923e-7 84441/1387/10046/2033/3516/3630/3171/207/55534/3280/9794 11 Variola_virus R-HSA-383280 Nuclear Receptor transcription pathway 12/346 52/10654 7.288619809054337e-8 7.8960047931422e-7 4.645962334426449e-7 5467/2908/5465/2100/7182/2101/5468/7421/6256/7376/2099/10062 12 Variola_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 13/346 63/10654 8.6126826787203e-8 9.227874298628893e-7 5.429626442917945e-7 3665/1387/6778/4615/7098/9208/2033/1499/8737/5970/4792/3661/29110 13 Variola_virus R-HSA-8983432 Interleukin-15 signaling 7/346 14/10654 1.0116303088307361e-7 1.0721082077282257e-6 6.308221033326672e-7 6776/6777/3561/3560/6774/3718/3716 7 Variola_virus R-HSA-9006931 Signaling by Nuclear Receptors 29/346 299/10654 1.290512504338177e-7 1.3529566577738955e-6 7.960716636834256e-7 7514/1025/2353/3725/1387/1956/8841/5467/5290/2033/2100/3276/2783/1950/5747/865/3065/207/6256/7376/2625/6714/2099/5594/10062/4609/5595/3326/6387 29 Variola_virus R-HSA-1266695 Interleukin-7 signaling 10/346 36/10654 1.3725880703003707e-7 1.4236950729179378e-6 8.37693727115008e-7 1154/8835/6776/6597/6777/3561/6774/3718/8651/3716 10 Variola_virus R-HSA-9009391 Extra-nuclear estrogen signaling 14/346 77/10654 1.4686742861389192e-7 1.5073236094583646e-6 8.869002614356908e-7 7514/2353/1956/5290/2100/3276/2783/1950/5747/207/6714/2099/5594/5595 14 Variola_virus R-HSA-9020591 Interleukin-12 signaling 11/346 47/10654 2.208010593574385e-7 2.242510759098985e-6 1.319480014800482e-6 3594/3717/3592/3458/7297/5062/3593/6775/3586/3595/3716 11 Variola_virus R-HSA-8939211 ESR-mediated signaling 24/346 223/10654 2.422762455917388e-7 2.4352509221850033e-6 1.4328871822842934e-6 7514/1025/2353/3725/1387/1956/5290/2033/2100/3276/2783/1950/5747/865/3065/207/2625/6714/2099/5594/4609/5595/3326/6387 24 Variola_virus R-HSA-186797 Signaling by PDGF 12/346 58/10654 2.6423449493619764e-7 2.628863597579517e-6 1.5468077308295136e-6 5159/5155/5290/6778/5335/6776/6777/5781/6774/6772/6714/5156 12 Variola_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 15/346 93/10654 2.7268125681784655e-7 2.6586422539740037e-6 1.5643293154286986e-6 8454/6500/2353/3665/1432/3725/4615/5599/5600/5970/4792/3654/5594/5595/51311 15 Variola_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 15/346 93/10654 2.7268125681784655e-7 2.6586422539740037e-6 1.5643293154286986e-6 8454/6500/2353/3665/1432/3725/4615/5599/5600/5970/4792/3654/5594/5595/51311 15 Variola_virus R-HSA-2262752 Cellular responses to stress 38/346 479/10654 2.8577301423447886e-7 2.758699889887296e-6 1.6232026342656696e-6 2475/2353/818/1432/3725/2932/1387/815/2908/5698/5599/2033/5600/9978/3312/1869/528/3456/6767/816/5702/6774/3569/7157/3297/5970/817/1639/7324/5696/22824/7422/5594/7415/5595/2056/3326/64223 38 Variola_virus R-HSA-388841 Costimulation by the CD28 family 13/346 70/10654 3.179707362292576e-7 3.0394261551326095e-6 1.7883803018054221e-6 2475/29126/3932/4067/5290/3127/2534/5781/5062/207/6714/7525/64223 13 Variola_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 15/346 95/10654 3.6322485486207787e-7 3.40523301433198e-6 2.0036188856258345e-6 8454/6500/2353/1432/3725/4615/5599/5600/7097/5970/4792/3654/5594/8651/5595 15 Variola_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 15/346 95/10654 3.6322485486207787e-7 3.40523301433198e-6 2.0036188856258345e-6 8454/6500/2353/1432/3725/4615/5599/5600/7097/5970/4792/3654/5594/8651/5595 15 Variola_virus R-HSA-1227986 Signaling by ERBB2 11/346 50/10654 4.3392163939078053e-7 4.029272365771534e-6 2.370799934516044e-6 2064/1956/5290/5581/5335/2534/1950/207/6714/7525/5580 11 Variola_virus R-HSA-2586552 Signaling by Leptin 6/346 11/10654 4.523842538825014e-7 4.1610815805230085e-6 2.4483556938030116e-6 3717/6776/6777/5781/6774/9021 6 Variola_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 15/346 97/10654 4.800750343573306e-7 4.374515499985022e-6 2.5739389446605526e-6 8454/6500/2353/3665/1432/3725/4615/5599/5600/5970/4792/3654/5594/5595/51311 15 Variola_virus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 8/346 24/10654 5.325068828552891e-7 4.807353803554694e-6 2.82861843232098e-6 7514/2353/1956/1950/5747/207/5594/5595 8 Variola_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 15/346 98/10654 5.503680299012868e-7 4.878262083215951e-6 2.87034044302585e-6 8454/6500/2353/1432/3725/4615/5599/5600/7097/5970/4792/3654/5594/8651/5595 15 Variola_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 15/346 98/10654 5.503680299012868e-7 4.878262083215951e-6 2.87034044302585e-6 8454/6500/2353/1432/3725/4615/5599/5600/7097/5970/4792/3654/5594/8651/5595 15 Variola_virus R-HSA-8953897 Cellular responses to external stimuli 38/346 493/10654 5.90345958927114e-7 5.185471260846272e-6 3.0511004989594798e-6 2475/2353/818/1432/3725/2932/1387/815/2908/5698/5599/2033/5600/9978/3312/1869/528/3456/6767/816/5702/6774/3569/7157/3297/5970/817/1639/7324/5696/22824/7422/5594/7415/5595/2056/3326/64223 38 Variola_virus R-HSA-446652 Interleukin-1 family signaling 18/346 140/10654 5.981401710201713e-7 5.207023810220241e-6 3.0637818910337723e-6 8454/6500/4615/5698/5599/3565/9978/5771/5781/5702/6774/5970/4792/5696/3654/29110/3553/3596 18 Variola_virus R-HSA-9006335 Signaling by Erythropoietin 8/346 25/10654 7.61101809766754e-7 6.567028889580401e-6 3.864000804125579e-6 4067/3717/5290/5335/6776/6777/2057/2056 8 Variola_virus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 6/346 12/10654 8.800688791454762e-7 7.526904887428415e-6 4.428786141590808e-6 7706/8772/64135/8737/57506/23586 6 Variola_virus R-HSA-5688426 Deubiquitination 27/346 297/10654 1.28116278188618e-6 1.0862032281208916e-5 6.39115529636584e-6 672/409/7048/7128/3416/11274/6502/9099/7706/7040/5698/7186/2033/64135/1540/5702/8737/7157/4792/8975/5696/2625/2099/57506/4609/7415/23586 27 Variola_virus R-HSA-3899300 SUMOylation of transcription cofactors 10/346 45/10654 1.3274217805476333e-6 1.115720893132709e-5 6.564835484559529e-6 10155/1387/9063/10401/2033/7329/4152/51588/10891/8554 10 Variola_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 14/346 92/10654 1.4169462780701418e-6 1.1807885650584516e-5 6.94768980250317e-6 8454/6500/2353/1432/3725/4615/5599/5600/5970/4792/3654/5594/5595/51311 14 Variola_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 17/346 134/10654 1.4906780614123004e-6 1.2317043304042314e-5 7.247275142459444e-6 8454/6500/2353/3725/4067/5290/5698/5335/5599/2534/5702/5970/4792/5062/5696/5594/5595 17 Variola_virus R-HSA-5689896 Ovarian tumor domain proteases 9/346 38/10654 2.5662395900168495e-6 2.08506966688869e-5 1.2268426110168272e-5 7128/7706/64135/8737/7157/2099/57506/7415/23586 9 Variola_virus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 9/346 38/10654 2.5662395900168495e-6 2.08506966688869e-5 1.2268426110168272e-5 1387/2064/1956/2033/3815/7329/7422/2099/4609 9 Variola_virus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 7/346 21/10654 2.814591084138675e-6 2.249365825438695e-5 1.3235134951299204e-5 4615/7098/8737/5970/4792/3661/29110 7 Variola_virus R-HSA-389513 CTLA4 inhibitory signaling 7/346 21/10654 2.814591084138675e-6 2.249365825438695e-5 1.3235134951299204e-5 3932/4067/2534/5781/207/6714/7525 7 Variola_virus R-HSA-73887 Death Receptor Signalling 17/346 141/10654 3.042886927033027e-6 2.4120445153310578e-005 1.4192326702892596e-5 7124/7128/7132/9099/8841/8772/836/4615/7186/5599/8717/1540/3065/8737/5970/4792/3654 17 Variola_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 13/346 85/10654 3.1879275693353115e-6 2.4668487143666102e-5 1.4514791355787342e-5 8454/6500/2353/1432/3725/4615/5599/5600/5970/4792/3654/5594/5595 13 Variola_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 13/346 85/10654 3.1879275693353115e-6 2.4668487143666102e-5 1.4514791355787342e-5 8454/6500/2353/1432/3725/4615/5599/5600/5970/4792/3654/5594/5595 13 Variola_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 13/346 85/10654 3.1879275693353115e-6 2.4668487143666102e-5 1.4514791355787342e-5 8454/6500/2353/1432/3725/4615/5599/5600/5970/4792/3654/5594/5595 13 Variola_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 8/346 30/10654 3.572319352690067e-6 2.7425286369077285e-5 1.6136875650361265e-5 7124/7128/7132/9099/7186/8717/1540/8737 8 Variola_virus R-HSA-373752 Netrin-1 signaling 10/346 50/10654 3.6988222886074256e-6 2.8174622901501875e-5 1.6577780816538214e-5 1432/5335/5599/2534/5600/5747/6300/5603/5781/6714 10 Variola_virus R-HSA-2871796 FCERI mediated MAPK activation 8/346 32/10654 6.064951838132223e-6 4.583975226495285e-5 2.69718380398373e-5 2353/3725/4067/5335/5599/5062/5594/5595 8 Variola_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 10/346 53/10654 6.43821572548103e-6 4.8286617941107726e-5 2.8411559274389966e-5 840/598/836/5599/1869/6774/7157/207/5594/5595 10 Variola_virus R-HSA-75893 TNF signaling 9/346 43/10654 7.691123588333862e-6 5.619924504708144e-5 3.306730207898449e-5 7124/7128/7132/9099/8772/7186/8717/1540/8737 9 Variola_virus R-HSA-933542 TRAF6 mediated NF-kB activation 7/346 24/10654 7.700542496627792e-6 5.619924504708144e-5 3.306730207898449e-5 7706/7186/64135/5970/4792/57506/23586 7 Variola_virus R-HSA-8877330 RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) 5/346 10/10654 7.733398596735805e-6 5.619924504708144e-5 3.306730207898449e-5 3558/50943/3559/865/3458 5 Variola_virus R-HSA-1980145 Signaling by NOTCH2 8/346 33/10654 7.781433929595891e-6 5.619924504708144e-5 3.306730207898449e-5 84441/2208/10046/2033/3516/55534/3280/9794 8 Variola_virus R-HSA-5357905 Regulation of TNFR1 signaling 8/346 33/10654 7.781433929595891e-6 5.619924504708144e-5 3.306730207898449e-5 7124/7128/7132/9099/7186/8717/1540/8737 8 Variola_virus R-HSA-202733 Cell surface interactions at the vascular wall 16/346 137/10654 8.998746571901162e-6 6.440191002210677e-5 3.7893701443506806e-5 3685/3932/4067/140885/6383/5290/7040/3687/5335/2534/3688/5781/3689/3684/6714/7525 16 Variola_virus R-HSA-6802952 Signaling by BRAF and RAF fusions 11/346 67/10654 9.10596381329324e-6 6.440191002210677e-5 3.7893701443506806e-5 409/818/10533/815/8805/3717/816/817/6714/5594/5595 11 Variola_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 10/346 55/10654 9.115347264667419e-6 6.440191002210677e-5 3.7893701443506806e-5 7128/1432/598/5600/1540/6300/5603/5970/3654/3326 10 Variola_virus R-HSA-187687 Signalling to ERKs 8/346 34/10654 9.890714224929387e-6 6.937731200939678e-5 4.0821198429280705e-5 1432/4914/5600/6300/5603/6714/5594/5595 8 Variola_virus R-HSA-376172 DSCAM interactions 5/346 11/10654 1.3800910549113615e-5 9.543182826514735e-5 5.615152108448616e-5 1432/5599/5600/6300/5603 5 Variola_virus R-HSA-4755510 SUMOylation of immune response proteins 5/346 11/10654 1.3800910549113615e-5 9.543182826514735e-5 5.615152108448616e-5 10401/5970/4792/7329/51588 5 Variola_virus R-HSA-76002 Platelet activation, signaling and aggregation 23/346 262/10654 1.4178435910579524e-5 9.735193670996506e-5 5.728130149196324e-5 409/4352/1432/3932/5155/4067/5290/5581/51368/81/7040/2534/2783/1950/5747/5781/207/7422/6714/5594/5595/7066/5580 23 Variola_virus R-HSA-6802957 Oncogenic MAPK signaling 11/346 71/10654 1.6155323966321567e-5 1.0991468422718482e-4 6.467314753448392e-5 409/818/10533/815/8805/3717/816/817/6714/5594/5595 11 Variola_virus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 9/346 47/10654 1.6571752391175558e-5 1.0991468422718482e-4 6.467314753448392e-5 409/818/815/3717/816/817/6714/5594/5595 9 Variola_virus R-HSA-6802949 Signaling by RAS mutants 9/346 47/10654 1.6571752391175558e-5 1.0991468422718482e-4 6.467314753448392e-5 409/818/815/3717/816/817/6714/5594/5595 9 Variola_virus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 9/346 47/10654 1.6571752391175558e-5 1.0991468422718482e-4 6.467314753448392e-5 409/818/815/3717/816/817/6714/5594/5595 9 Variola_virus R-HSA-9649948 Signaling downstream of RAS mutants 9/346 47/10654 1.6571752391175558e-5 1.0991468422718482e-4 6.467314753448392e-5 409/818/815/3717/816/817/6714/5594/5595 9 Variola_virus R-HSA-448424 Interleukin-17 signaling 11/346 72/10654 1.8523350131390598e-5 1.2202882687909347e-4 7.180103713803611e-5 8454/6500/3605/2353/1432/3725/5599/5600/3654/5594/5595 11 Variola_virus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 12/346 86/10654 2.0003607010254122e-5 1.3089608614092464e-4 7.701847983460612e-5 4067/5290/5581/5335/2534/5747/6714/5594/7525/5595/3326/5580 12 Variola_virus R-HSA-166520 Signaling by NTRKs 13/346 101/10654 2.204643985472147e-5 1.4330185905568957e-4 8.431796295314528e-5 1432/5290/4914/5335/2534/5600/6300/5603/5781/6774/6714/5594/5595 13 Variola_virus R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 5/346 12/10654 2.303008317051945e-5 1.4870417941229447e-4 8.749665617241618e-5 4067/3717/5290/2057/2056 5 Variola_virus R-HSA-167044 Signalling to RAS 6/346 20/10654 2.9600200815595555e-5 1.886287306876187e-4 1.109880250739565e-4 1432/4914/5600/6300/5603/6714 6 Variola_virus R-HSA-3232118 SUMOylation of transcription factors 6/346 20/10654 2.9600200815595555e-5 1.886287306876187e-4 1.109880250739565e-4 9063/10401/7157/7329/51588/8554 6 Variola_virus R-HSA-450294 MAP kinase activation 10/346 64/10654 3.641378662753974e-5 2.2915801554025797e-4 1.3483521562152831e-4 8454/6500/2353/1432/3725/5599/5600/3654/5594/5595 10 Variola_virus R-HSA-171007 p38MAPK events 5/346 13/10654 3.6430248624348704e-5 2.2915801554025797e-4 1.3483521562152831e-4 1432/5600/6300/5603/6714 5 Variola_virus R-HSA-75153 Apoptotic execution phase 9/346 52/10654 3.877637842369391e-5 2.423523651480869e-4 1.4259869258375965e-4 840/999/836/1499/5747/5062/3836/5580/6709 9 Variola_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 6/346 21/10654 4.031444470817826e-5 2.50360405034865e-4 1.4731057570202584e-4 1387/4067/2534/2033/5970/5062 6 Variola_virus R-HSA-6807070 PTEN Regulation 15/346 140/10654 4.785072396397135e-5 2.94848603519078e-4 1.7348716752269635e-4 2475/3725/8841/5698/5468/5702/3065/7157/207/8975/5696/5371/5594/5595/64223 15 Variola_virus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 7/346 31/10654 4.8083003035418874e-5 2.94848603519078e-4 1.7348716752269635e-4 2353/1432/3725/5599/5600/5594/5595 7 Variola_virus R-HSA-187037 Signaling by NTRK1 (TRKA) 11/346 80/10654 5.092665375238223e-5 3.103342963035792e-4 1.8259885720426524e-4 1432/5290/4914/5335/5600/6300/5603/6774/6714/5594/5595 11 Variola_virus R-HSA-389357 CD28 dependent PI3K/Akt signaling 6/346 22/10654 5.3927230140990304e-5 3.265779465059972e-4 1.9215652452984452e-4 2475/3932/5290/2534/207/64223 6 Variola_virus R-HSA-3371568 Attenuation phase 5/346 14/10654 5.516577007980673e-5 3.320162088136516e-4 1.9535636577969244e-4 1387/2033/3312/3297/3326 5 Variola_virus R-HSA-5621481 C-type lectin receptors (CLRs) 15/346 142/10654 5.6455866045107475e-5 3.376961312514097e-4 1.986983984151345e-4 8454/6500/1387/4067/5698/2534/2033/5702/5970/4792/5062/5696/3553/6714/5580 15 Variola_virus R-HSA-8866910 TFAP2 (AP-2) family regulates transcription of growth factors and their receptors 5/346 15/10654 8.055486685214368e-5 4.789085072002445e-4 2.817869219153935e-4 2064/1956/3815/7422/2099 5 Variola_virus R-HSA-449836 Other interleukin signaling 6/346 24/10654 9.20737094099174e-5 5.44071919240421e-4 3.201286866245932e-4 282618/836/3588/7297/163702/3716 6 Variola_virus R-HSA-1236394 Signaling by ERBB4 9/346 58/10654 9.455010573585907e-5 5.55339476460618e-4 3.2675845038708425e-4 1956/5290/2670/6776/1950/10413/6714/2099/6387 9 Variola_virus R-HSA-168638 NOD1/2 Signaling Pathway 7/346 36/10654 1.327298564565359e-4 7.74919820629476e-4 4.559582210451438e-4 7128/1432/5600/1540/6300/5603/3654 7 Variola_virus R-HSA-8943724 Regulation of PTEN gene transcription 9/346 61/10654 1.413401919977744e-4 8.202778999870836e-4 4.8264664560643516e-4 2475/3725/8841/5468/3065/7157/5594/5595/64223 9 Variola_virus R-HSA-180292 GAB1 signalosome 5/346 17/10654 1.5731680325214824e-4 8.969817729289155e-4 5.277787489838152e-4 1956/5290/1950/5781/6714 5 Variola_virus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 5/346 17/10654 1.5731680325214824e-4 8.969817729289155e-4 5.277787489838152e-4 4615/7098/8737/5970/4792 5 Variola_virus R-HSA-6788467 IL-6-type cytokine receptor ligand interactions 5/346 17/10654 1.5731680325214824e-4 8.969817729289155e-4 5.277787489838152e-4 3717/5008/7297/3572/3716 5 Variola_virus R-HSA-111465 Apoptotic cleavage of cellular proteins 7/346 38/10654 1.8977028289962974e-4 0.0010757327082973197 6.329547379455214e-4 840/999/836/1499/5747/5580/6709 7 Variola_virus R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 4/346 10/10654 1.9657140216722998e-4 0.0011078446075898799 6.518491888113194e-4 1432/5600/6300/10891 4 Variola_virus R-HSA-1912408 Pre-NOTCH Transcription and Translation 11/346 93/10654 2.0344439737693127e-4 0.0011399901577155633 6.707634396275109e-4 84441/3725/1387/10046/2033/1869/4854/3516/7157/55534/9794 11 Variola_virus R-HSA-5654741 Signaling by FGFR3 7/346 40/10654 2.6513587920780335e-4 0.00147718561272919 8.691672431173103e-4 2261/5290/5335/5781/6714/5594/5595 7 Variola_virus R-HSA-5689880 Ub-specific processing proteases 18/346 220/10654 2.943383271138767e-4 0.001630479950080953 9.593647209653111e-4 409/3416/11274/6502/9099/5698/7186/64135/1540/5702/8737/7157/4792/8975/5696/2625/4609/23586 18 Variola_virus R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 4/346 11/10654 3.0101168309186823e-4 0.001630479950080953 9.593647209653111e-4 1387/2033/7422/2056 4 Variola_virus R-HSA-3371378 Regulation by c-FLIP 4/346 11/10654 3.0101168309186823e-4 0.001630479950080953 9.593647209653111e-4 8772/7186/8717/8737 4 Variola_virus R-HSA-5218900 CASP8 activity is inhibited 4/346 11/10654 3.0101168309186823e-4 0.001630479950080953 9.593647209653111e-4 8772/7186/8717/8737 4 Variola_virus R-HSA-69416 Dimerization of procaspase-8 4/346 11/10654 3.0101168309186823e-4 0.001630479950080953 9.593647209653111e-4 8772/7186/8717/8737 4 Variola_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 10/346 82/10654 3.0651184045158645e-4 0.0016510996930403138 9.714972552841792e-4 8454/6500/2932/5698/1499/9978/5702/3065/5696/1452 10 Variola_virus R-HSA-9604323 Negative regulation of NOTCH4 signaling 8/346 54/10654 3.2179743228882867e-4 0.0017239148158330105 0.0010143412411649025 8454/6500/5698/55294/9978/5702/207/5696 8 Variola_virus R-HSA-453279 Mitotic G1-G1/S phases 14/346 149/10654 3.4358756006536167e-4 0.0018256108603600593 0.0010741785899014654 8454/6500/4067/3717/6502/5698/1869/4174/5702/3065/207/5696/6714/4609 14 Variola_virus R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 6/346 30/10654 3.4452553672435993e-4 0.0018256108603600593 0.0010741785899014654 818/815/816/817/5594/5595 6 Variola_virus R-HSA-1489509 DAG and IP3 signaling 7/346 42/10654 3.6287495593743713e-4 0.0019124490921027092 0.0011252736898202174 818/815/5581/5335/816/817/5580 7 Variola_virus R-HSA-8941858 Regulation of RUNX3 expression and activity 8/346 55/10654 3.661021700400947e-4 0.001919083955855335 0.0011291776042549608 57154/7040/5698/2033/865/5702/5696/6714 8 Variola_virus R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 10/346 84/10654 3.735434731899442e-4 0.0019476197131561262 0.0011459678744076532 7124/1387/8841/7040/5465/2033/5468/5970/6256/10891 10 Variola_virus R-HSA-1989781 PPARA activates gene expression 12/346 117/10654 4.073087359544875e-4 0.0021123724338065176 0.0012429073969495838 1387/8841/196/5465/2033/2101/5468/133522/6256/7376/10891/10062 12 Variola_virus R-HSA-400253 Circadian Clock 9/346 70/10654 4.101628632574374e-4 0.002115919532677257 0.0012449944888627312 8454/6500/1387/8841/2908/5465/2033/6256/10891 9 Variola_virus R-HSA-111932 CaMK IV-mediated phosphorylation of CREB 4/346 12/10654 4.4000248305254305e-4 0.002234387609251195 0.0013147004016646707 818/815/816/817 4 Variola_virus R-HSA-2029481 FCGR activation 4/346 12/10654 4.4000248305254305e-4 0.002234387609251195 0.0013147004016646707 4067/2534/6714/7525 4 Variola_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 4/346 12/10654 4.4000248305254305e-4 0.002234387609251195 0.0013147004016646707 3665/7098/3661/29110 4 Variola_virus R-HSA-445144 Signal transduction by L1 5/346 21/10654 4.647858450222262e-4 0.0023480113932469976 0.0013815559614786652 3685/1956/3688/5594/5595 5 Variola_virus R-HSA-202403 TCR signaling 12/346 119/10654 4.7588050425378606e-4 0.0023794025212689304 0.0014000263148087094 8454/6500/3932/5290/5698/3127/5335/5702/5970/4792/5062/5696 12 Variola_virus R-HSA-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 12/346 119/10654 4.7588050425378606e-4 0.0023794025212689304 0.0014000263148087094 1387/8841/196/5465/2033/2101/5468/133522/6256/7376/10891/10062 12 Variola_virus R-HSA-69231 Cyclin D associated events in G1 7/346 44/10654 4.875275790058599e-4 0.0024128903021863623 0.0014197303262527044 8454/6500/4067/3717/6502/1869/6714 7 Variola_virus R-HSA-69236 G1 Phase 7/346 44/10654 4.875275790058599e-4 0.0024128903021863623 0.0014197303262527044 8454/6500/4067/3717/6502/1869/6714 7 Variola_virus R-HSA-1251985 Nuclear signaling by ERBB4 6/346 32/10654 4.97784903449484e-4 0.0024315907953147706 0.0014307335853673954 2670/6776/10413/6714/2099/6387 6 Variola_virus R-HSA-5673000 RAF activation 6/346 32/10654 4.97784903449484e-4 0.0024315907953147706 0.0014307335853673954 818/815/3717/816/817/6714 6 Variola_virus R-HSA-9020702 Interleukin-1 signaling 11/346 103/10654 4.987878554491837e-4 0.0024315907953147706 0.0014307335853673954 8454/6500/4615/5698/9978/5702/5970/4792/5696/3654/3553 11 Variola_virus R-HSA-1250196 SHC1 events in ERBB2 signaling 5/346 22/10654 5.8562661410494e-4 0.0028407261131956044 0.0016714663769949844 2064/1956/5581/1950/5580 5 Variola_virus R-HSA-9022692 Regulation of MECP2 expression and activity 6/346 33/10654 5.919891054491602e-4 0.0028573731574897585 0.0016812613990088185 818/815/8841/816/3065/817 6 Variola_virus R-HSA-8951664 Neddylation 18/346 234/10654 6.181065342755125e-4 0.002960214326283235 0.0017417725320640896 8454/6500/1154/83987/9655/6502/55832/5698/1642/8835/8450/9306/55294/9978/25879/5702/5696/9021 18 Variola_virus R-HSA-111461 Cytochrome c-mediated apoptotic response 4/346 13/10654 6.193679205761845e-4 0.002960214326283235 0.0017417725320640896 840/836/5594/5595 4 Variola_virus R-HSA-5610783 Degradation of GLI2 by the proteasome 8/346 60/10654 6.682844654609905e-4 0.0031629968632255617 0.0018610885726941227 8454/6500/2932/5698/9978/5702/5696/1452 8 Variola_virus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 8/346 60/10654 6.682844654609905e-4 0.0031629968632255617 0.0018610885726941227 8454/6500/2932/5698/9978/5702/5696/1452 8 Variola_virus R-HSA-373753 Nephrin family interactions 5/346 23/10654 7.285838908892052e-4 0.003431735717956401 0.002019212919067464 6711/5290/81/2534/6709 5 Variola_virus R-HSA-1912422 Pre-NOTCH Expression and Processing 11/346 109/10654 8.072883680320819e-4 0.003784164225150384 0.0022265797600075133 84441/3725/1387/10046/2033/1869/4854/3516/7157/55534/9794 11 Variola_virus R-HSA-8986944 Transcriptional Regulation by MECP2 8/346 62/10654 8.348056613224407e-4 0.0038915494651854026 0.0022897645975989683 818/815/8841/5468/816/3065/817/3654 8 Variola_virus R-HSA-73893 DNA Damage Bypass 7/346 48/10654 8.381798848091635e-4 0.0038915494651854026 0.0022897645975989683 9636/7706/1642/8450/9978/9246/7415 7 Variola_virus R-HSA-9027284 Erythropoietin activates RAS 4/346 14/10654 8.450487807747346e-4 0.0039048462618737735 0.0022975883538150677 4067/3717/2057/2056 4 Variola_virus R-HSA-5260271 Diseases of Immune System 5/346 24/10654 8.960865702258587e-4 0.004082637411075758 0.0024021996102955873 4615/7098/7097/5970/4792 5 Variola_virus R-HSA-5602358 Diseases associated with the TLR signaling cascade 5/346 24/10654 8.960865702258587e-4 0.004082637411075758 0.0024021996102955873 4615/7098/7097/5970/4792 5 Variola_virus R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 5/346 24/10654 8.960865702258587e-4 0.004082637411075758 0.0024021996102955873 1432/5600/5594/5595/5580 5 Variola_virus R-HSA-375165 NCAM signaling for neurite out-growth 8/346 63/10654 9.2972963609094e-4 0.004216215791575193 0.0024807963362034873 6710/6711/2534/5747/6714/5594/5595/6709 8 Variola_virus R-HSA-1500931 Cell-Cell communication 12/346 129/10654 9.823158224243572e-4 0.004434064476221057 0.0026089772086806758 140885/6711/999/5290/81/2534/3688/1499/5747/5781/6714/6709 12 Variola_virus R-HSA-1592230 Mitochondrial biogenesis 10/346 95/10654 9.978075858456778e-4 0.004483236848845788 0.0026379099407513678 1432/1387/8841/5465/5600/2101/6300/133522/6256/10891 10 Variola_virus R-HSA-983169 Class I MHC mediated antigen processing & presentation 24/346 371/10654 0.0010239070174206492 0.004579400651307949 0.0026944921511069717 8454/6500/57154/3685/6047/10533/81559/6502/4615/5698/55294/7097/9978/55008/151636/5702/7324/5696/10075/9021/9246/8651/51191/3106 24 Variola_virus R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 5/346 25/10654 0.0010906417989402326 0.004811654995324556 0.002831149228018227 2475/2932/2931/207/64223 5 Variola_virus R-HSA-9006115 Signaling by NTRK2 (TRKB) 5/346 25/10654 0.0010906417989402326 0.004811654995324556 0.002831149228018227 5290/5335/2534/5781/6714 5 Variola_virus R-HSA-9620244 Long-term potentiation 5/346 25/10654 0.0010906417989402326 0.004811654995324556 0.002831149228018227 818/815/816/817/6714 5 Variola_virus R-HSA-5637810 Constitutive Signaling by EGFRvIII 4/346 15/10654 0.0011230465676556767 0.004888260729751271 0.002876223587276052 1956/5290/5335/1950 4 Variola_virus R-HSA-5637812 Signaling by EGFRvIII in Cancer 4/346 15/10654 0.0011230465676556767 0.004888260729751271 0.002876223587276052 1956/5290/5335/1950 4 Variola_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 4/346 15/10654 0.0011230465676556767 0.004888260729751271 0.002876223587276052 3665/4615/3654/51311 4 Variola_virus R-HSA-9614085 FOXO-mediated transcription 8/346 65/10654 0.0011454835765203396 0.0049637621649214715 0.0029206481834085853 604/1387/2908/2033/3630/3065/207/10891 8 Vesicular_stomatitis_Indiana_virus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 204/771 244/10654 3.110239323544047e-200 3.489688521016421e-197 1.7941169992654086e-197 10450/7536/2962/10921/51690/10898/22938/29894/1993/8449/27238/1665/55749/23165/11017/51503/988/22827/3178/10286/23451/53981/6637/199746/9972/23450/348995/4928/10236/23524/2963/56949/79023/5437/10250/6635/81929/53938/57122/6629/5441/6634/5434/23636/5440/4670/10914/5094/5903/23020/6633/10569/220988/23225/51593/6432/8683/51691/6431/8021/9775/23658/3192/10189/3183/5438/85313/10084/6430/6632/51340/9716/10762/5431/6434/10283/9092/51362/56001/6627/7175/55110/54883/6396/9295/5093/24148/22794/129401/23511/6936/81608/10946/5435/8896/6427/10594/4686/9785/9631/8189/23398/83443/6625/3312/10465/84844/5433/6631/10713/10482/27339/8175/51645/10949/5356/2733/51692/53371/11051/55660/11338/6426/3181/84950/5439/1655/10421/9343/11193/3188/29107/51729/3185/9129/1660/55696/4116/23350/5430/25949/84991/3190/10907/10291/5432/55746/1477/23283/10978/79869/22916/9416/65109/9939/6626/4904/11157/5436/5546/56259/2521/5725/1479/26121/9879/11100/22826/51639/51585/3191/10285/10523/285755/6429/1478/6428/8480/10772/9410/24144/6638/57819/57794/10992/11325/55339/9128/57703/23279/4927/10262/10181/6628/9688/27316/6636/27258/3184/3187/1994/8106/25804/79902 204 Vesicular_stomatitis_Indiana_virus R-HSA-72163 mRNA Splicing - Major Pathway 176/771 183/10654 2.5020846057496437e-198 1.40366946382555e-195 7.216538757635815e-196 10450/7536/2962/10921/51690/10898/22938/29894/1993/8449/27238/1665/55749/11017/51503/988/22827/3178/10286/23451/53981/6637/199746/23450/10236/23524/2963/56949/5437/10250/6635/53938/6629/5441/6634/5434/5440/4670/10914/5094/23020/6633/10569/220988/51593/6432/8683/51691/6431/9775/23658/3192/10189/3183/5438/85313/10084/6430/6632/51340/9716/5431/6434/10283/9092/51362/6627/55110/54883/9295/5093/24148/22794/6936/81608/10946/5435/8896/6427/10594/4686/9785/8189/23398/83443/6625/3312/10465/84844/5433/6631/10713/27339/8175/51645/10949/5356/51692/11051/55660/11338/6426/3181/84950/5439/1655/10421/9343/11193/3188/51729/3185/9129/1660/55696/4116/23350/5430/25949/84991/3190/10907/10291/5432/1477/23283/10978/79869/22916/9416/65109/9939/6626/4904/11157/5436/5546/56259/2521/5725/1479/26121/9879/11100/22826/51639/51585/3191/10285/10523/285755/6429/1478/6428/10772/9410/24144/6638/57819/57794/10992/11325/55339/9128/57703/10262/10181/6628/27316/6636/27258/3184/3187/1994/8106/25804 176 Vesicular_stomatitis_Indiana_virus R-HSA-72172 mRNA Splicing 176/771 191/10654 9.243687783460398e-189 3.4571392310141888e-186 1.77738277380221e-186 10450/7536/2962/10921/51690/10898/22938/29894/1993/8449/27238/1665/55749/11017/51503/988/22827/3178/10286/23451/53981/6637/199746/23450/10236/23524/2963/56949/5437/10250/6635/53938/6629/5441/6634/5434/5440/4670/10914/5094/23020/6633/10569/220988/51593/6432/8683/51691/6431/9775/23658/3192/10189/3183/5438/85313/10084/6430/6632/51340/9716/5431/6434/10283/9092/51362/6627/55110/54883/9295/5093/24148/22794/6936/81608/10946/5435/8896/6427/10594/4686/9785/8189/23398/83443/6625/3312/10465/84844/5433/6631/10713/27339/8175/51645/10949/5356/51692/11051/55660/11338/6426/3181/84950/5439/1655/10421/9343/11193/3188/51729/3185/9129/1660/55696/4116/23350/5430/25949/84991/3190/10907/10291/5432/1477/23283/10978/79869/22916/9416/65109/9939/6626/4904/11157/5436/5546/56259/2521/5725/1479/26121/9879/11100/22826/51639/51585/3191/10285/10523/285755/6429/1478/6428/10772/9410/24144/6638/57819/57794/10992/11325/55339/9128/57703/10262/10181/6628/27316/6636/27258/3184/3187/1994/8106/25804 176 Vesicular_stomatitis_Indiana_virus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 83/771 86/10654 2.602105462763503e-92 5.839124658441301e-90 3.0020079865145257e-90 5716/9491/5715/701/8454/23198/6500/5718/1017/51343/7311/5711/9184/5689/8945/5701/5688/143471/26271/5706/25906/5687/5705/5684/6502/5347/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/119504/5682/7316/10213/5709/246184/5694/5699/5695/5710/890/5700/122706/7321/5707/5702/991/4085/8900/51529/983/5693/5721/7324/5696/5719/6790/64682/5691/29945/10393/8697/5714/5690/4751/9212/9232/7314/996/5704/6233/51434/5717/51433/9861 83 Vesicular_stomatitis_Indiana_virus R-HSA-453276 Regulation of mitotic cell cycle 83/771 86/10654 2.602105462763503e-92 5.839124658441301e-90 3.0020079865145257e-90 5716/9491/5715/701/8454/23198/6500/5718/1017/51343/7311/5711/9184/5689/8945/5701/5688/143471/26271/5706/25906/5687/5705/5684/6502/5347/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/119504/5682/7316/10213/5709/246184/5694/5699/5695/5710/890/5700/122706/7321/5707/5702/991/4085/8900/51529/983/5693/5721/7324/5696/5719/6790/64682/5691/29945/10393/8697/5714/5690/4751/9212/9232/7314/996/5704/6233/51434/5717/51433/9861 83 Vesicular_stomatitis_Indiana_virus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 78/771 80/10654 7.199299749080605e-88 1.346269053078073e-85 6.921432039466967e-86 5716/9491/5715/701/8454/23198/6500/5718/1017/51343/7311/5711/9184/5689/8945/5701/5688/143471/26271/5706/25906/5687/5705/5684/5347/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/119504/5682/7316/10213/5709/246184/5694/5699/5695/5710/890/5700/122706/7321/5707/5702/991/4085/8900/51529/983/5693/5721/7324/5696/5719/64682/5691/29945/10393/8697/5714/5690/7314/996/5704/6233/51434/5717/51433/9861 78 Vesicular_stomatitis_Indiana_virus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 74/771 76/10654 3.472765305740436e-83 5.566346675772527e-81 2.861767500068811e-81 5716/9491/5715/701/23198/5718/7311/5711/9184/5689/5701/5688/143471/5706/25906/5687/5705/5684/5347/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/119504/5682/7316/10213/5709/246184/5694/5699/5695/5710/890/5700/122706/7321/5707/5702/991/4085/8900/51529/983/5693/5721/7324/5696/5719/64682/5691/29945/10393/8697/5714/5690/4751/9232/7314/996/5704/6233/51434/5717/51433/9861 74 Vesicular_stomatitis_Indiana_virus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 72/771 73/10654 2.182914476226472e-82 3.0615375529076273e-80 1.5739962275948774e-80 5716/9491/5715/701/23198/5718/7311/5711/9184/5689/5701/5688/143471/5706/25906/5687/5705/5684/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/119504/5682/7316/10213/5709/246184/5694/5699/5695/5710/890/5700/122706/7321/5707/5702/991/4085/8900/51529/983/5693/5721/7324/5696/5719/64682/5691/29945/10393/8697/5714/5690/4751/7314/996/5704/6233/51434/5717/51433/9861 72 Vesicular_stomatitis_Indiana_virus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 73/771 75/10654 5.12501312340116e-82 6.389183027173446e-80 3.2848037328933753e-80 5716/9491/5715/701/23198/5718/7311/5711/9184/5689/5701/5688/143471/5706/25906/5687/5705/5684/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/119504/5682/7316/10213/5709/246184/5694/5699/5695/5710/890/5700/122706/7321/5707/5702/991/4085/8900/51529/983/5693/5721/7324/5696/5719/64682/5691/29945/10393/8697/5714/5690/4751/9232/7314/996/5704/6233/51434/5717/51433/9861 73 Vesicular_stomatitis_Indiana_virus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 71/771 72/10654 3.2547866242412165e-81 3.0432254936655376e-79 1.5645816404247253e-79 5716/9491/5715/23198/5718/51343/7311/5711/5689/5701/5688/143471/5706/25906/5687/5705/5684/6502/5347/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/119504/5682/7316/10213/5709/246184/5694/5699/5695/5710/5700/122706/7321/5707/5702/991/51529/5693/5721/7324/5696/5719/6790/64682/5691/29945/10393/8697/5714/5690/9212/9232/7314/996/5704/6233/51434/5717/51433/9861 71 Vesicular_stomatitis_Indiana_virus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 71/771 72/10654 3.2547866242412165e-81 3.0432254936655376e-79 1.5645816404247253e-79 5716/9491/5715/701/23198/5718/7311/5711/9184/5689/5701/5688/143471/5706/25906/5687/5705/5684/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/119504/5682/7316/10213/5709/246184/5694/5699/5695/5710/890/5700/122706/7321/5707/5702/991/4085/8900/51529/983/5693/5721/7324/5696/5719/64682/5691/29945/10393/8697/5714/5690/7314/996/5704/6233/51434/5717/51433/9861 71 Vesicular_stomatitis_Indiana_virus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 71/771 72/10654 3.2547866242412165e-81 3.0432254936655376e-79 1.5645816404247253e-79 5716/9491/5715/23198/898/5718/1017/51343/7311/5711/5689/5701/5688/143471/5706/25906/5687/5705/9134/5684/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/990/29882/119504/5682/7316/10213/5709/246184/5694/5699/5695/5710/890/5700/122706/7321/5707/5702/8900/51529/5693/5721/7324/5696/5719/64682/5691/29945/10393/8697/5714/5690/7314/996/5704/6233/51434/5717/51433/9861 71 Vesicular_stomatitis_Indiana_virus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 66/771 67/10654 2.3441317444204513e-75 2.0231660132613433e-73 1.0401491465120708e-73 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/25906/5687/5705/5684/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/119504/5682/7316/10213/5709/246184/5694/5699/5695/5710/5700/122706/7321/5707/5702/991/51529/5693/5721/7324/5696/5719/64682/5691/29945/10393/8697/5714/5690/9232/7314/996/5704/6233/51434/5717/51433/9861 66 Vesicular_stomatitis_Indiana_virus R-HSA-69052 Switching of origins to a post-replicative state 77/771 90/10654 2.73006534462295e-75 2.1879523690478212e-73 1.1248690292130652e-73 5716/9491/5715/8454/23198/6500/898/4998/5718/1017/51343/7311/5711/5689/5701/5688/143471/5706/25906/5687/5705/9134/5684/6502/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/990/29882/119504/5682/7316/10213/5709/246184/5694/5699/9978/5695/5710/890/5700/122706/7321/5707/5702/8900/51529/5693/5721/7324/5696/5719/64682/5691/29945/10393/8697/5714/5690/4171/7314/996/5704/6233/51434/5717/51433/9861 77 Vesicular_stomatitis_Indiana_virus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 62/771 63/10654 1.1063131565337678e-70 8.275222410872583e-69 4.2544534019684545e-69 5716/9491/5715/5718/51343/7311/5711/5689/5701/5688/5706/25906/5687/5705/5684/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/119504/5682/7316/10213/5709/246184/5694/5699/5695/5710/5700/7321/5707/5702/51529/5693/5721/7324/5696/5719/64682/5691/29945/10393/8697/5714/5690/7314/996/5704/6233/51434/5717/51433/9861 62 Vesicular_stomatitis_Indiana_virus R-HSA-162909 Host Interactions of HIV factors 87/771 129/10654 5.741372556334075e-69 4.0261375051292705e-67 2.069915895309917e-67 5716/9491/5715/23198/6500/7514/1025/5718/23165/7311/5711/5689/5905/9972/348995/8945/5701/4928/5688/143471/3837/79023/5706/5687/81929/51606/57122/5705/23636/5684/5903/8065/23225/10197/5720/5685/8021/5683/5698/5708/10762/5692/5686/5713/7175/6396/129401/23511/5682/9631/7316/10213/5709/5694/5699/9978/1104/5695/5710/53371/5700/122706/5707/5702/5902/5901/5062/55746/5693/5721/5696/5719/3836/5691/5714/5690/8480/23279/4927/9688/7314/5704/6233/5717/9861/4869/79902 87 Vesicular_stomatitis_Indiana_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 68/771 82/10654 1.412376245488049e-64 9.321683220221123e-63 4.7924593345353e-63 5716/9491/5715/8454/23198/6500/5519/5718/7311/5711/5689/2932/8945/5701/5688/143471/5706/5518/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/324/5528/5682/7316/1499/10213/5709/5694/5699/9978/5525/5695/8312/5529/5710/5700/139285/122706/5707/5702/3065/5526/5693/5721/5696/1452/5719/5691/5714/5690/7314/5704/6233/5527/5515/5717/9861/5516 68 Vesicular_stomatitis_Indiana_virus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 75/771 102/10654 5.324552395612806e-64 3.3189709932653157e-62 1.7063477852607123e-62 5716/9491/5715/8454/23198/6500/8792/7124/5718/944/330/7311/5711/5971/5689/8945/5701/5688/143471/329/5706/5687/115650/5705/4050/7187/5684/23291/10197/10673/5720/5685/5683/5698/5708/7186/5692/5686/5713/51330/5682/7316/10213/5709/5694/5699/5695/5710/5700/970/122706/5707/9020/5702/5693/9040/5721/8742/5696/5719/5691/8600/7133/4791/5714/5690/4049/959/8740/7314/5704/6233/4055/5717/9861 75 Vesicular_stomatitis_Indiana_virus R-HSA-69239 Synthesis of DNA 80/771 119/10654 3.1473435231029446e-63 1.858589175221844e-61 9.555369809752986e-62 5716/9491/5715/8454/23198/6500/898/4998/5718/1017/51343/7311/6119/5711/6118/5689/5701/5688/143471/5706/25906/5687/5705/9134/5684/6502/10197/5720/5685/11065/5683/5698/5708/6117/5692/8881/5686/5713/990/29882/119504/5682/7316/10213/5709/246184/5694/5699/9978/5695/5710/890/5700/122706/7321/5707/5702/8900/51529/5693/5721/7324/5696/5719/64682/5691/29945/10393/8697/5714/5690/4171/7314/996/5704/6233/51434/5717/51433/9861 80 Vesicular_stomatitis_Indiana_virus R-HSA-162906 HIV Infection 109/771 233/10654 4.1529792687998347e-63 2.3298213697967074e-61 1.1978066522643736e-61 5716/9491/5715/2962/23198/6500/404672/7514/1025/5718/23165/7311/5711/5689/5905/9972/348995/8945/5701/4928/5688/143471/2963/3837/79023/5706/5437/5687/81929/51606/57122/5705/5441/5434/23636/5440/5684/5903/55048/8065/23225/10197/5720/5685/8021/5683/5438/7251/5698/5708/10762/5692/5431/5686/128866/5713/7175/6396/129401/23511/5435/5682/4686/9631/7316/10213/5709/5694/5699/9978/5433/1104/5695/5710/53371/5700/5439/122706/5707/2959/5702/5430/5902/5901/5062/5432/55746/22916/5693/5721/5696/5436/5719/3836/5691/5714/5690/8480/23279/4927/9688/8148/7314/5704/6233/5717/9861/4869/79902 109 Vesicular_stomatitis_Indiana_virus R-HSA-69620 Cell Cycle Checkpoints 121/771 293/10654 1.4599754779271602e-62 7.800440410639399e-61 4.010358706286135e-61 5716/9491/5715/701/672/23198/7514/898/5519/4998/5718/1017/7158/2810/7311/6119/5711/9184/6118/5689/5905/348995/5701/4928/5688/143471/79023/5706/5518/472/25906/5687/81929/57122/5705/9134/5684/5903/5347/10197/5720/5685/11065/5683/5698/5708/580/6117/5692/8881/5686/5713/990/29882/6396/119504/5528/5682/7316/84126/10213/5709/246184/5694/5699/25936/5525/51512/993/5695/80776/5501/5529/25909/5710/890/5700/122706/7321/5707/5702/991/5526/7157/4085/8900/51529/55746/983/5693/1026/5721/7324/5696/5719/64682/5691/29945/10393/80152/8697/5714/5690/8924/9212/4171/51588/23279/7314/996/5704/6233/5527/51434/5515/5717/1027/51433/9861/79902/5516 121 Vesicular_stomatitis_Indiana_virus R-HSA-1234174 Cellular response to hypoxia 64/771 75/10654 1.9497731122600907e-62 9.943842872526462e-61 5.112323758461865e-61 5716/9491/5715/23198/5718/7311/5711/3091/5689/5701/5688/1387/143471/5706/5687/5705/2034/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/2033/5682/64344/7316/54583/10213/5709/5694/5699/9978/112399/5695/5710/5700/126374/122706/7321/5707/7428/5702/8453/5693/84962/5721/5696/5719/5691/7422/5714/5690/768/7314/5704/6233/5717/8994/9861 64 Vesicular_stomatitis_Indiana_virus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 60/771 66/10654 2.5203488436533445e-62 1.2294919141648054e-60 6.321057969437222e-61 5716/9491/5715/23198/5718/7311/5711/3091/5689/5701/5688/143471/5706/5687/5705/2034/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/64344/7316/54583/10213/5709/5694/5699/9978/112399/5695/5710/5700/126374/122706/7321/5707/7428/5702/8453/5693/84962/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/8994/9861 60 Vesicular_stomatitis_Indiana_virus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 57/771 60/10654 3.821680676246577e-62 1.715170287499464e-60 8.818025307718418e-61 5716/9491/5715/8454/6500/898/5718/1017/7311/5711/5689/5701/5688/5706/5687/5705/9134/5684/6502/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/595/10213/5709/5694/5699/5695/1163/5710/890/5700/5707/5702/8900/5693/1026/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/1027/9861 57 Vesicular_stomatitis_Indiana_virus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 57/771 60/10654 3.821680676246577e-62 1.715170287499464e-60 8.818025307718418e-61 5716/9491/5715/8454/23198/6500/5718/7311/5711/5971/5689/8945/5701/5688/143471/5706/5687/5705/5684/23291/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/9020/5702/5970/5693/9040/5721/5696/5719/5691/4791/5714/5690/7314/5704/6233/5717/9861 57 Vesicular_stomatitis_Indiana_virus R-HSA-2555396 Mitotic Metaphase and Anaphase 101/771 202/10654 5.4843309463933745e-62 2.3666997391743717e-60 1.2167665419528621e-60 5716/9491/5715/701/23198/4000/7514/5519/5718/7311/5711/9184/5689/5905/348995/5701/4928/5688/143471/26271/79023/5706/5518/25906/5687/81929/57122/5705/5684/5903/5347/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/6396/119504/5528/5682/7316/10213/5709/246184/5694/5699/25936/5525/5695/80776/5501/5529/25909/55869/5710/5700/122706/7321/5707/5702/991/5526/4085/51529/55746/7112/5693/5721/7324/5696/5719/64682/5691/29945/10393/80152/8697/5714/5690/9212/9232/23279/7314/996/5704/6233/5527/51434/5515/5717/51433/9861/79902/5516 101 Vesicular_stomatitis_Indiana_virus R-HSA-2467813 Separation of Sister Chromatids 98/771 190/10654 8.569250978381747e-62 3.560999851016415e-60 1.8307795462585568e-60 5716/9491/5715/701/23198/7514/5519/5718/7311/5711/9184/5689/5905/348995/5701/4928/5688/143471/79023/5706/5518/25906/5687/81929/57122/5705/5684/5903/5347/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/6396/119504/5528/5682/7316/10213/5709/246184/5694/5699/25936/5525/5695/80776/5501/5529/25909/55869/5710/5700/122706/7321/5707/5702/991/5526/4085/51529/55746/5693/5721/7324/5696/5719/64682/5691/29945/10393/80152/8697/5714/5690/9212/9232/23279/7314/996/5704/6233/5527/51434/5515/5717/51433/9861/79902/5516 98 Vesicular_stomatitis_Indiana_virus R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 54/771 55/10654 2.2846312173945598e-61 8.839159399712745e-60 4.5443844179027904e-60 5716/9491/5715/8454/23198/6500/5718/51343/7311/5711/5689/8945/5701/5688/143471/26271/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/991/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 54 Vesicular_stomatitis_Indiana_virus R-HSA-4641257 Degradation of AXIN 54/771 55/10654 2.2846312173945598e-61 8.839159399712745e-60 4.5443844179027904e-60 5716/9491/81847/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/64750/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/8312/80351/5710/5700/122706/5707/5702/8658/5693/8313/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 54 Vesicular_stomatitis_Indiana_virus R-HSA-69306 DNA Replication 81/771 127/10654 3.195509940821738e-61 1.1951207178673299e-59 6.144348938843201e-60 51053/5716/9491/5715/8454/23198/6500/898/4998/5718/1017/51343/7311/6119/5711/6118/5689/5701/5688/143471/5706/25906/5687/5705/9134/5684/6502/10197/5720/5685/11065/5683/5698/5708/6117/5692/8881/5686/5713/990/29882/119504/5682/7316/10213/5709/246184/5694/5699/9978/5695/5710/890/5700/122706/7321/5707/5702/8900/51529/5693/5721/7324/5696/5719/64682/5691/29945/10393/8697/5714/5690/4171/7314/996/5704/6233/51434/5717/51433/9861 81 Vesicular_stomatitis_Indiana_virus R-HSA-4641258 Degradation of DVL 55/771 57/10654 4.187094861588549e-61 1.4990432136459776e-59 7.70687382566841e-60 5716/9491/5715/1857/23198/23072/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/8452/5713/5682/7316/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/1856/5693/5721/5696/5719/5691/5714/5690/7314/59349/5704/6233/1855/5717/9861 55 Vesicular_stomatitis_Indiana_virus R-HSA-68882 Mitotic Anaphase 100/771 201/10654 4.275346063874446e-61 1.4990432136459776e-59 7.70687382566841e-60 5716/9491/5715/701/23198/4000/7514/5519/5718/7311/5711/9184/5689/5905/348995/5701/4928/5688/143471/79023/5706/5518/25906/5687/81929/57122/5705/5684/5903/5347/10197/5720/5685/11065/5683/5698/5708/5692/8881/5686/5713/29882/6396/119504/5528/5682/7316/10213/5709/246184/5694/5699/25936/5525/5695/80776/5501/5529/25909/55869/5710/5700/122706/7321/5707/5702/991/5526/4085/51529/55746/7112/5693/5721/7324/5696/5719/64682/5691/29945/10393/80152/8697/5714/5690/9212/9232/23279/7314/996/5704/6233/5527/51434/5515/5717/51433/9861/79902/5516 100 Vesicular_stomatitis_Indiana_virus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 56/771 59/10654 5.3802659803744553e-61 1.8292904333273148e-59 9.404739257560452e-60 5716/9491/5715/8454/23198/6500/5718/7311/5711/5971/5689/8945/5701/5688/143471/5706/5687/5705/5684/23291/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/9020/5702/5693/9040/5721/5696/5719/5691/4791/5714/5690/7314/5704/6233/5717/9861 56 Vesicular_stomatitis_Indiana_virus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 53/771 54/10654 3.3116162520429113e-60 1.0928333631741607e-58 5.618469678388593e-59 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/5701/23194/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/6790/5691/5714/5690/7314/5704/6233/5717/9861 53 Vesicular_stomatitis_Indiana_virus R-HSA-5610780 Degradation of GLI1 by the proteasome 56/771 60/10654 7.535363675887314e-60 2.2850481200933964e-58 1.1747878504655046e-58 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/2735/5692/5686/5713/5682/7316/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/8650/83737/5693/5721/5696/5719/5691/5714/51684/5690/7314/5704/6233/5717/9861 56 Vesicular_stomatitis_Indiana_virus R-HSA-5610783 Degradation of GLI2 by the proteasome 56/771 60/10654 7.535363675887314e-60 2.2850481200933964e-58 1.1747878504655046e-58 5716/9491/5715/8454/23198/6500/2736/5718/7311/5711/5689/2932/8945/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/5693/5721/5696/1452/5719/5691/5714/51684/5690/7314/5704/6233/5717/9861 56 Vesicular_stomatitis_Indiana_virus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 56/771 60/10654 7.535363675887314e-60 2.2850481200933964e-58 1.1747878504655046e-58 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/2932/8945/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/2737/5682/7316/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/5693/5721/5696/1452/5719/5691/5714/51684/5690/7314/5704/6233/5717/9861 56 Vesicular_stomatitis_Indiana_virus R-HSA-1169091 Activation of NF-kappaB in B cells 58/771 67/10654 2.133974865866057e-57 6.300841577636094e-56 3.239385668960109e-56 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/23291/10197/5720/5685/4794/5683/5698/5708/5692/5686/4790/5713/5966/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5970/4792/5693/5721/5696/5719/4793/5691/5714/5690/7314/5704/6233/5717/9861 58 Vesicular_stomatitis_Indiana_virus R-HSA-69242 S Phase 87/771 161/10654 4.435719502770074e-57 1.2761223800276983e-55 6.560794298294199e-56 5716/9491/5715/8454/23198/6500/898/4998/5718/1017/51343/7311/6119/5711/6118/5689/2932/5701/5688/143471/5706/25906/5687/5705/9134/5684/6502/10197/5720/5685/11065/5683/5698/5708/6117/5692/8881/5686/5713/990/29882/119504/5682/7316/595/10213/5709/246184/5694/5699/9978/993/5695/1163/5710/890/5700/122706/7321/5707/5702/8900/51529/5693/1026/5721/7324/5696/5719/64682/5691/29945/10393/8697/5714/5690/4171/4609/7314/996/5704/6233/51434/5717/1027/51433/9861 87 Vesicular_stomatitis_Indiana_virus R-HSA-69615 G1/S DNA Damage Checkpoints 58/771 68/10654 1.3550514866639559e-56 3.8009194200923964e-55 1.954126880768021e-55 5716/9491/5715/23198/898/5718/1017/7311/5711/5689/5701/5688/143471/5706/472/5687/5705/9134/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/993/5695/5710/890/5700/122706/5707/5702/7157/8900/5693/1026/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/1027/9861 58 Vesicular_stomatitis_Indiana_virus R-HSA-69563 p53-Dependent G1 DNA Damage Response 57/771 66/10654 2.739985324460004e-56 7.31967508105744e-55 3.763187864170632e-55 5716/9491/5715/23198/898/5718/1017/7311/5711/5689/5701/5688/143471/5706/472/5687/5705/9134/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/890/5700/122706/5707/5702/7157/8900/5693/1026/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/1027/9861 57 Vesicular_stomatitis_Indiana_virus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 57/771 66/10654 2.739985324460004e-56 7.31967508105744e-55 3.763187864170632e-55 5716/9491/5715/23198/898/5718/1017/7311/5711/5689/5701/5688/143471/5706/472/5687/5705/9134/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/890/5700/122706/5707/5702/7157/8900/5693/1026/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/1027/9861 57 Vesicular_stomatitis_Indiana_virus R-HSA-5632684 Hedgehog 'on' state 64/771 85/10654 8.75653574910036e-56 2.2848449094164198e-54 1.1746833758891061e-54 5716/9491/5715/23198/2736/8405/3549/5718/79577/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/6469/10197/5720/5685/5683/64750/5698/5708/2735/5692/5686/8452/5713/2737/339745/5682/7316/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/8650/83737/5693/5721/5696/1452/5719/5691/5714/51684/5690/50846/7314/5704/6233/5717/9861 64 Vesicular_stomatitis_Indiana_virus R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 49/771 50/10654 1.4380225737675741e-55 3.666957563107314e-54 1.8852544747000733e-54 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5062/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Vesicular_stomatitis_Indiana_virus R-HSA-180534 Vpu mediated degradation of CD4 50/771 52/10654 2.4234344565742282e-55 5.785305234630392e-54 2.974338369994798e-54 5716/9491/5715/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Vesicular_stomatitis_Indiana_virus R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 50/771 52/10654 2.4234344565742282e-55 5.785305234630392e-54 2.974338369994798e-54 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/472/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/7157/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Vesicular_stomatitis_Indiana_virus R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 50/771 52/10654 2.4234344565742282e-55 5.785305234630392e-54 2.974338369994798e-54 5716/9491/5715/23198/5718/7311/5711/5689/2932/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/595/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Vesicular_stomatitis_Indiana_virus R-HSA-68949 Orc1 removal from chromatin 58/771 71/10654 2.20497397026737e-54 5.154126655499978e-53 2.649837139707278e-53 5716/9491/5715/8454/23198/6500/4998/5718/1017/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/6502/10197/5720/5685/5683/5698/5708/5692/5686/5713/990/5682/7316/10213/5709/5694/5699/9978/5695/5710/890/5700/122706/5707/5702/8900/5693/5721/5696/5719/5691/5714/5690/4171/7314/5704/6233/5717/9861 58 Vesicular_stomatitis_Indiana_virus R-HSA-180585 Vif-mediated degradation of APOBEC3G 50/771 54/10654 5.0348826637151595e-53 1.1528853772833487e-51 5.927208807123324e-52 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/8065/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Vesicular_stomatitis_Indiana_virus R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 49/771 52/10654 5.536132177292818e-53 1.194526981331258e-51 6.141296423393653e-52 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/993/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Vesicular_stomatitis_Indiana_virus R-HSA-69610 p53-Independent DNA Damage Response 49/771 52/10654 5.536132177292818e-53 1.194526981331258e-51 6.141296423393653e-52 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/993/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Vesicular_stomatitis_Indiana_virus R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 49/771 52/10654 5.536132177292818e-53 1.194526981331258e-51 6.141296423393653e-52 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/993/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Vesicular_stomatitis_Indiana_virus R-HSA-5387390 Hh mutants abrogate ligand secretion 52/771 59/10654 2.040598314079239e-52 4.3199081290507665e-51 2.220949108471545e-51 5716/9491/5715/23198/3549/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/6469/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/84447/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/50846/7314/5704/6233/5717/9861 52 Vesicular_stomatitis_Indiana_virus R-HSA-8941858 Regulation of RUNX3 expression and activity 50/771 55/10654 5.16908738945859e-52 1.0740214909208405e-50 5.521754170415805e-51 5716/9491/5715/5718/7311/5711/5689/5701/5688/5706/5687/5705/5684/10197/5720/5685/7040/5683/64750/5698/5708/5692/5686/5713/2033/5682/7316/10213/5709/5694/5699/5695/864/5710/5700/5707/5702/5693/5721/5696/5719/5691/5714/5690/6714/7314/5704/6233/5717/9861 50 Vesicular_stomatitis_Indiana_virus R-HSA-169911 Regulation of Apoptosis 49/771 53/10654 6.845869345770549e-52 1.396557346537192e-50 7.179973974128729e-51 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5062/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Vesicular_stomatitis_Indiana_virus R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 48/771 51/10654 7.651229929027817e-52 1.5329785679230733e-50 7.881342107344444e-51 5716/9491/5715/23198/5718/5711/5689/5701/5688/143471/5706/5687/4946/5705/5684/4947/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/10213/5709/5694/5699/5695/5710/5700/122706/5707/4953/5702/5693/5721/5696/5719/5691/5714/5690/51686/5704/5717/9861 48 Vesicular_stomatitis_Indiana_virus R-HSA-5658442 Regulation of RAS by GAPs 55/771 68/10654 3.865897957952964e-51 7.609714927760046e-50 3.912303011926546e-50 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/399473/5683/5698/5708/5692/5686/8452/5713/3845/5682/7316/10213/5709/5694/5699/9978/5695/5710/200734/5700/122706/4763/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/161742/5717/9861 55 Vesicular_stomatitis_Indiana_virus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 50/771 56/10654 4.5027774491731403e-51 8.562908979614006e-50 4.402358683580519e-50 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/3312/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/3184/5717/9861 50 Vesicular_stomatitis_Indiana_virus R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 50/771 56/10654 4.5027774491731403e-51 8.562908979614006e-50 4.402358683580519e-50 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/6469/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/84447/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Vesicular_stomatitis_Indiana_virus R-HSA-5663202 Diseases of signal transduction 124/771 377/10654 5.0766417813546945e-51 9.39745241438778e-50 4.831413756529229e-50 5716/9491/5715/8454/7409/2962/23198/6500/4000/22938/3082/5519/3549/5718/7311/5711/5689/2932/5701/5688/1387/143471/2963/5706/5437/5159/5518/5155/5687/5705/5441/5434/5440/5684/3717/6464/1956/6469/10197/4088/5720/5685/7040/5683/5438/5698/5708/5692/5431/5686/5713/324/3845/79885/2033/6776/5528/2100/2549/5435/5682/84447/6777/4686/7316/1499/10213/5728/5709/5694/5699/9978/5433/5525/1950/5695/8312/5529/80351/55869/5710/5700/139285/5439/122706/4763/5707/5702/3065/6774/89780/5430/5526/5432/4233/8658/22916/5693/1026/5721/5696/5436/1452/11140/5719/5691/5714/5690/5245/6772/6714/50846/6654/4609/7314/5704/6233/5527/2885/5515/5717/1027/9861/5516 124 Vesicular_stomatitis_Indiana_virus R-HSA-5663205 Infectious disease 125/771 383/10654 5.10913188304505e-51 9.39745241438778e-50 4.831413756529229e-50 5716/9491/5715/2962/23198/6500/10898/404672/7514/1025/5718/23165/7311/5711/5689/5905/9972/348995/8945/5701/4928/5688/143471/2963/3837/79023/5706/5437/3838/6123/5687/81929/51606/57122/5705/5441/5610/5434/23636/5440/5684/5903/55048/8065/23225/10197/2926/999/5720/5685/8021/7040/5683/5438/7251/5698/5708/10762/5692/5431/5686/128866/5713/7175/6396/129401/23511/5606/5435/5682/4686/9631/7316/1499/10213/5709/5694/5699/9978/5433/1104/5695/5710/53371/5700/3843/5439/122706/5707/2959/5702/5608/5430/5902/5901/5062/5432/4233/55746/22916/5693/5721/5696/5436/5719/3836/5691/5714/5690/8480/6714/23279/4927/9688/8148/7314/5704/6233/2885/8106/3841/5717/9861/4869/79902 125 Vesicular_stomatitis_Indiana_virus R-HSA-9604323 Negative regulation of NOTCH4 signaling 49/771 54/10654 6.900120392388241e-51 1.248699206493485e-49 6.419806409216904e-50 5716/9491/5715/8454/6500/5718/7311/5711/5689/5701/5688/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/4855/7316/10213/5709/5694/5699/9978/5695/5710/5700/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Vesicular_stomatitis_Indiana_virus R-HSA-8948751 Regulation of PTEN stability and activity 55/771 69/10654 1.77880730414301e-50 3.1679711035689795e-49 1.6287157939354544e-49 5716/9491/81847/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5728/5709/5694/5699/5695/80351/5710/5700/122706/5707/5702/1457/8658/5693/5721/5696/4734/5719/5691/5714/5690/7314/5704/6233/11060/5717/9861 55 Vesicular_stomatitis_Indiana_virus R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 51/771 59/10654 1.8223042622390635e-50 3.194727159737858e-49 1.6424716047812613e-49 51053/5716/9491/5715/23198/4998/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/990/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 51 Vesicular_stomatitis_Indiana_virus R-HSA-69541 Stabilization of p53 50/771 57/10654 3.422040360574211e-50 5.906968130098868e-49 3.0368876398294215e-49 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/472/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/7157/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Vesicular_stomatitis_Indiana_virus R-HSA-72202 Transport of Mature Transcript to Cytoplasm 60/771 84/10654 5.201653700157101e-50 8.842811290267071e-49 4.546261926134117e-49 10921/10898/29894/23165/53981/199746/9972/348995/4928/79023/10250/81929/57122/23636/5903/10569/23225/6432/8683/6431/8021/9775/10189/6430/10762/51362/56001/7175/55110/6396/9295/22794/129401/23511/81608/6427/4686/9785/9631/8189/10482/2733/51692/53371/11338/6426/29107/4116/55746/22916/65109/9939/6429/6428/8480/55339/23279/4927/9688/79902 60 Vesicular_stomatitis_Indiana_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 56/771 73/10654 1.119213638374185e-49 1.8742652272475157e-48 9.635963453716473e-49 5716/9491/5715/8454/23198/6500/5718/7311/5711/59269/5689/2932/5701/5688/143471/5706/5687/5705/5684/6502/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/11059/5693/5721/5696/5719/5691/5714/5690/6772/7314/5704/6233/5717/9861 56 Vesicular_stomatitis_Indiana_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 60/771 85/10654 1.6516082228185526e-49 2.725153567650612e-48 1.4010546534126425e-48 5716/9491/5715/8454/6500/898/5718/1017/51343/7311/5711/5689/5701/5688/5706/5687/5705/9134/5684/6502/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/595/10213/5709/5694/5699/993/5695/1163/5710/890/5700/5707/5702/8900/5693/1026/5721/5696/5719/5691/5714/5690/4609/7314/5704/6233/5717/1027/9861 60 Vesicular_stomatitis_Indiana_virus R-HSA-69206 G1/S Transition 73/771 131/10654 3.4070479722498544e-49 5.540156267919329e-48 2.8483025000654775e-48 51053/5716/9491/5715/8454/6500/898/5519/4998/5718/1017/7311/6119/5711/6118/5689/5701/5688/26271/5706/5518/5687/5705/9134/5684/6502/10197/5720/5685/5683/5698/5708/6117/5692/5686/5713/990/5682/7316/595/10213/5709/5694/5699/993/5695/1163/5710/890/5700/5707/5702/3065/8900/983/5693/1026/5721/5696/5719/5691/5714/5690/4171/4609/7314/5704/6233/5515/5717/1027/9861/5516 73 Vesicular_stomatitis_Indiana_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 59/771 83/10654 5.519225259213702e-49 8.721930620898273e-48 4.484114814009057e-48 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/23291/10197/5720/5685/4794/5683/5698/5708/5692/5686/4790/5713/3845/5966/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5970/4792/5693/5721/5696/5719/4793/5691/5714/5690/7314/5704/6233/5717/9861 59 Vesicular_stomatitis_Indiana_virus R-HSA-69202 Cyclin E associated events during G1/S transition 59/771 83/10654 5.519225259213702e-49 8.721930620898273e-48 4.484114814009057e-48 5716/9491/5715/8454/6500/898/5718/1017/7311/5711/5689/5701/5688/5706/5687/5705/9134/5684/6502/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/595/10213/5709/5694/5699/993/5695/1163/5710/890/5700/5707/5702/8900/5693/1026/5721/5696/5719/5691/5714/5690/4609/7314/5704/6233/5717/1027/9861 59 Vesicular_stomatitis_Indiana_virus R-HSA-5358346 Hedgehog ligand biogenesis 52/771 65/10654 6.496461877341403e-48 1.0123653092190352e-46 5.204767702899253e-47 5716/9491/5715/23198/3549/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/6469/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/84447/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/50846/7314/5704/6233/5717/9861 52 Vesicular_stomatitis_Indiana_virus R-HSA-453279 Mitotic G1-G1/S phases 76/771 149/10654 2.0142278503733305e-47 3.095840613861475e-46 1.5916321009438864e-46 51053/5716/9491/5715/8454/6500/898/5519/4998/5718/1017/7311/6119/5711/6118/5689/5701/5688/26271/5706/5518/5687/5705/9134/5684/3717/6502/10197/5720/5685/5683/5698/5708/6117/5692/5686/5713/990/5682/7316/595/10213/5709/5694/5699/993/5695/1163/5710/890/5700/5707/5702/3065/8900/1859/983/5693/1026/5721/5696/5719/5691/5714/5690/6714/4171/4609/7314/5704/6233/5515/5717/1027/9861/5516 76 Vesicular_stomatitis_Indiana_virus R-HSA-5678895 Defective CFTR causes cystic fibrosis 50/771 61/10654 4.1059379348467226e-47 6.225489679591922e-46 3.2006457870497927e-46 5716/9491/5715/23198/1080/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/79139/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Vesicular_stomatitis_Indiana_virus R-HSA-68886 M Phase 122/771 395/10654 7.644992346190481e-47 1.1289433348598107e-45 5.804118092721421e-46 5716/9491/5715/701/23198/4000/7514/5519/5718/23165/7311/5711/9184/4926/5689/5905/9972/348995/5701/4928/5688/143471/26271/79023/5706/5518/25906/5687/81929/57122/5705/23636/5684/5903/5347/23225/10197/5720/5685/11065/8021/5683/5698/5708/10762/5692/8881/5686/5713/7175/29882/6396/119504/129401/23511/5528/5682/9631/7316/10213/5709/246184/5694/5699/25936/5525/5695/80776/5501/5529/25909/55869/5710/53371/5700/122706/7321/5707/5702/991/5526/4085/5108/1457/51529/55746/983/7112/5693/5721/7324/5696/5719/64682/5691/2801/29945/10393/80152/8697/5714/5690/4751/8480/9212/9232/23279/4927/9688/7314/5577/996/5704/6233/5527/51434/5515/5717/51433/9861/79902/5516 122 Vesicular_stomatitis_Indiana_virus R-HSA-4608870 Asymmetric localization of PCP proteins 51/771 64/10654 7.647031501724208e-47 1.1289433348598107e-45 5.804118092721421e-46 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/144165/10197/5720/5685/5683/64750/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/1856/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 51 Vesicular_stomatitis_Indiana_virus R-HSA-68867 Assembly of the pre-replicative complex 52/771 68/10654 4.727905370141217e-46 6.88923353934863e-45 3.541889463892532e-45 51053/5716/9491/5715/23198/4998/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/990/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/4171/7314/5704/6233/5717/9861 52 Vesicular_stomatitis_Indiana_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 62/771 101/10654 1.927878132293782e-45 2.773178544145671e-44 1.425745231439936e-44 5716/9491/5715/8454/23198/6500/5718/7311/5711/5971/5689/8945/5701/5688/143471/5706/5687/5705/5684/23291/10197/5720/5685/5683/5698/5708/5692/5686/4790/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/7321/5707/9020/5702/5970/4792/5693/9040/5721/5696/5719/10768/5691/4791/5714/5690/6714/7314/5704/6233/5717/9861 62 Vesicular_stomatitis_Indiana_virus R-HSA-2262752 Cellular responses to stress 133/771 479/10654 2.754270757032525e-45 3.911761758722143e-44 2.0111130910777133e-44 5716/9491/5715/23198/898/2882/5718/1017/23165/51343/7311/6119/5711/3091/6118/5689/9972/348995/2932/5701/4928/5688/1387/143471/79023/5706/472/25906/5687/81929/51606/57122/5705/9134/23636/2034/5684/5903/23225/10197/5720/5685/11065/8021/5683/3309/5698/5708/8726/6117/10762/5692/8881/5686/4790/5713/7175/29882/5599/6396/2033/119504/129401/23511/5606/5682/64344/9631/57332/7316/54583/10213/5709/246184/5694/5699/9978/3312/112399/5695/1915/5710/890/53371/5700/126374/122706/7321/5707/7428/5702/2146/5608/9531/6774/7157/8453/5970/8900/51529/55746/5693/84962/1026/5721/7324/5696/6045/5719/64682/5691/29945/10393/7422/8697/5714/5690/8480/768/23279/4927/9688/7314/996/5704/6233/51434/5717/8994/1027/51433/9861/79902 133 Vesicular_stomatitis_Indiana_virus R-HSA-2871837 FCERI mediated NF-kB activation 56/771 82/10654 5.65721424973961e-45 7.934242985259804e-44 4.079149222180667e-44 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/23291/10197/5720/5685/5683/5698/5708/5692/5686/4790/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/7321/5707/5702/5970/4792/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 56 Vesicular_stomatitis_Indiana_virus R-HSA-351202 Metabolism of polyamines 48/771 59/10654 5.914056603055285e-45 8.192063590898803e-44 4.211699829076409e-44 5716/9491/5715/23198/5718/5711/5689/5701/5688/143471/5706/5687/4946/5705/5684/4947/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/10213/5709/5694/5699/5695/5710/5700/122706/5707/4953/5702/5693/5721/5696/5719/5691/5714/5690/51686/5704/5717/9861 48 Vesicular_stomatitis_Indiana_virus R-HSA-8878159 Transcriptional regulation by RUNX3 60/771 96/10654 1.1418037808554057e-44 1.5623217586826405e-43 8.032201179830071e-44 5716/9491/5715/22938/5718/7311/5711/5689/5701/5688/1387/5706/5687/5705/5684/10197/4088/5720/5685/7040/5683/64750/5698/5708/5692/5686/5713/3845/2033/5682/7316/595/1499/10213/5709/5694/5699/5695/864/5710/5700/5707/5702/7157/5693/1026/5721/5696/5719/5691/10413/5714/5690/6714/4609/7314/5704/6233/5717/9861 60 Vesicular_stomatitis_Indiana_virus R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 44/771 50/10654 2.1660992238948019e-44 2.9281485894095994e-43 1.5054183572534578e-43 5716/9491/5715/23198/5718/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/5704/5717/9861 44 Vesicular_stomatitis_Indiana_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 64/771 112/10654 4.00869262652977e-44 5.3544680082933354e-43 2.752836540524203e-43 5716/9491/5715/8454/7409/23198/6500/5718/7311/5711/5689/5777/8945/5701/5688/143471/5706/5687/5705/5684/23291/10197/5720/5685/4794/5683/5698/5708/5692/5686/4790/5713/3845/5966/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5970/4792/5693/5721/5696/5719/10768/4793/5691/5714/5690/6654/7314/5704/6233/2885/5717/9861 64 Vesicular_stomatitis_Indiana_virus R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 53/771 75/10654 7.459789673944133e-44 9.846922369606255e-43 5.062495035692118e-43 10921/23165/199746/9972/348995/4928/79023/10250/81929/57122/23636/5903/10569/23225/6432/8683/6431/8021/9775/10189/6430/10762/51362/56001/7175/55110/6396/9295/22794/129401/23511/6427/4686/9785/9631/10482/2733/53371/11338/6426/29107/4116/55746/22916/65109/9939/6429/6428/8480/23279/4927/9688/79902 53 Vesicular_stomatitis_Indiana_virus R-HSA-8953897 Cellular responses to external stimuli 133/771 493/10654 9.811318918713447e-44 1.2800348635809869e-42 6.5809091400917615e-43 5716/9491/5715/23198/898/2882/5718/1017/23165/51343/7311/6119/5711/3091/6118/5689/9972/348995/2932/5701/4928/5688/1387/143471/79023/5706/472/25906/5687/81929/51606/57122/5705/9134/23636/2034/5684/5903/23225/10197/5720/5685/11065/8021/5683/3309/5698/5708/8726/6117/10762/5692/8881/5686/4790/5713/7175/29882/5599/6396/2033/119504/129401/23511/5606/5682/64344/9631/57332/7316/54583/10213/5709/246184/5694/5699/9978/3312/112399/5695/1915/5710/890/53371/5700/126374/122706/7321/5707/7428/5702/2146/5608/9531/6774/7157/8453/5970/8900/51529/55746/5693/84962/1026/5721/7324/5696/6045/5719/64682/5691/29945/10393/7422/8697/5714/5690/8480/768/23279/4927/9688/7314/996/5704/6233/51434/5717/8994/1027/51433/9861/79902 133 Vesicular_stomatitis_Indiana_virus R-HSA-69002 DNA Replication Pre-Initiation 56/771 85/10654 1.2443176486426387e-43 1.6047406916977476e-42 8.250285196081862e-43 51053/5716/9491/5715/23198/4998/5718/1017/7311/6119/5711/6118/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/6117/5692/5686/5713/990/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/4171/7314/5704/6233/5717/9861 56 Vesicular_stomatitis_Indiana_virus R-HSA-9020702 Interleukin-1 signaling 61/771 103/10654 2.2088972899737516e-43 2.8163440447165332e-42 1.447937458021072e-42 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/351/23291/10197/5720/5685/5683/5698/5708/5692/5686/4790/5713/5682/7316/10213/5709/5694/5699/9978/5695/79155/5710/5700/122706/5707/5702/5608/5970/4792/5693/5721/5696/5719/4793/5691/4791/5714/5690/7314/5704/6233/5717/9861 61 Vesicular_stomatitis_Indiana_virus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 53/771 77/10654 6.890483397339613e-43 8.686654350353983e-42 4.465978594609235e-42 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/5347/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/51512/5695/5710/5700/122706/5707/5702/7157/983/5693/1026/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 53 Vesicular_stomatitis_Indiana_virus R-HSA-8878166 Transcriptional regulation by RUNX2 64/771 121/10654 2.722974595393238e-41 3.3946416622569034e-40 1.74525155353859e-40 5716/9491/5715/8454/23198/6500/2736/3549/5718/7311/5711/59269/5689/2932/5701/5688/143471/5706/5687/5705/5684/6502/10197/5720/5685/5683/5698/5708/5692/5686/5713/2737/5682/7316/595/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/11059/983/5693/1026/5721/5696/5719/5691/10413/5714/5690/6772/6714/7314/5704/6233/5717/9861 64 Vesicular_stomatitis_Indiana_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 55/771 88/10654 5.241257740596105e-41 6.462298005438275e-40 3.322393570672835e-40 5716/9491/5715/23198/7514/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/8021/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/3312/5695/5710/5700/122706/5707/5702/3842/5693/54512/5721/5696/5719/5691/5714/5690/7314/5704/6233/3184/1994/5717/9861 55 Vesicular_stomatitis_Indiana_virus R-HSA-72165 mRNA Splicing - Minor Pathway 43/771 52/10654 5.933321403725338e-41 7.236072407586771e-40 3.720206097530304e-40 2962/23451/6637/23450/2963/5437/6635/5441/6634/5434/5440/23020/6633/6432/6431/5438/6632/5431/24148/5435/6427/10594/4686/83443/5433/6426/5439/9343/5430/10907/5432/22916/9416/4904/5436/51639/9410/57819/10992/11325/10262/6628/6636 43 Vesicular_stomatitis_Indiana_virus R-HSA-9013694 Signaling by NOTCH4 53/771 82/10654 1.1217232293937313e-40 1.3533047993330824e-39 6.957604184581379e-40 5716/9491/5715/8454/6500/22938/5718/7311/5711/5689/5701/5688/1387/5706/5687/5705/5684/10197/4088/5720/5685/5683/5698/5708/5692/5686/5713/2033/5682/4855/7316/10213/5709/5694/5699/9978/5695/5710/5700/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 53 Vesicular_stomatitis_Indiana_virus R-HSA-5358351 Signaling by Hedgehog 70/771 149/10654 1.2301244578654878e-40 1.4682974911968907e-39 7.548804063944988e-40 5716/9491/5715/8454/23198/6500/2736/8405/3549/5718/79577/7311/5711/5689/2932/8945/5701/5688/143471/5706/5687/5705/5684/6469/10197/5720/5685/5683/64750/5698/5708/2735/5692/5686/8452/5713/2737/339745/5682/84447/7316/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/8650/83737/5693/5721/5696/1452/5719/5691/5714/51684/5690/50846/7314/5577/5704/6233/5717/9861 70 Vesicular_stomatitis_Indiana_virus R-HSA-5610787 Hedgehog 'off' state 61/771 113/10654 4.3717759122309635e-40 5.163297445813833e-39 2.6545520220527072e-39 5716/9491/5715/8454/23198/6500/2736/5718/7311/5711/5689/2932/8945/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/2735/5692/5686/5713/2737/5682/7316/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/8650/83737/5693/5721/5696/1452/5719/5691/5714/51684/5690/7314/5577/5704/6233/5717/9861 61 Vesicular_stomatitis_Indiana_virus R-HSA-202424 Downstream TCR signaling 57/771 98/10654 5.724675686355856e-40 6.690714708428407e-39 3.439827057152423e-39 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/23291/10197/5720/5685/5683/5698/5708/5692/5686/4790/5713/5682/7316/10213/5728/5709/5694/5699/5695/5710/5700/122706/7321/5707/5702/5970/4792/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 57 Vesicular_stomatitis_Indiana_virus R-HSA-5619115 Disorders of transmembrane transporters 75/771 176/10654 8.583389727853904e-40 9.928415747064e-39 5.104392372071557e-39 5716/9491/5715/23198/1080/5718/23165/7311/5711/5689/9972/348995/5701/4928/5688/143471/79023/5706/5687/81929/57122/5705/23636/5684/5903/23225/10197/5720/5685/8021/5683/5698/5708/10762/5692/5686/5713/7175/6396/129401/23511/5682/9631/7316/10213/5709/5694/5699/5695/5710/53371/5700/122706/5707/5702/79139/55746/55630/5693/5721/5696/5719/5691/5714/5690/8480/23279/4927/9688/7314/5704/6233/5717/9861/79902 75 Vesicular_stomatitis_Indiana_virus R-HSA-201681 TCF dependent signaling in response to WNT 86/771 233/10654 1.0984278947530663e-39 1.2575878550132043e-38 6.46550468662385e-39 5716/9491/81847/5715/1857/23198/7514/5519/23072/5718/79577/7311/5711/5689/2932/8945/5701/5688/1387/143471/5706/5518/5687/5705/5684/10197/5720/5685/5683/64750/5698/5708/5692/5686/8452/5713/324/2033/5528/5682/7316/1499/10213/5709/5694/5699/9978/5525/5695/8312/864/5529/80351/5710/5700/139285/122706/5707/5702/3065/1856/89780/5526/1457/8658/5693/8313/5721/5696/1452/5719/5691/5714/5690/4609/7314/59349/5704/6233/5527/1855/123169/5515/5717/9861/5516 86 Vesicular_stomatitis_Indiana_virus R-HSA-446652 Interleukin-1 family signaling 67/771 140/10654 1.4423024273147457e-39 1.6346094176233786e-38 8.403846147458592e-39 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/5777/8945/5701/5688/143471/5706/5687/5705/5684/351/23291/10197/4088/5720/5685/5683/5698/5708/5692/5686/4790/5713/5599/5682/7316/10213/5709/5694/5699/9978/5695/79155/5771/5710/5700/122706/5707/5702/5608/27178/6774/5970/4792/5693/5721/5696/5719/4793/5691/4791/5714/5690/7314/5704/6233/5717/9861 67 Vesicular_stomatitis_Indiana_virus R-HSA-73856 RNA Polymerase II Transcription Termination 47/771 67/10654 9.616572989028992e-39 1.0789794893690528e-37 5.547244208408303e-38 10921/10898/29894/53981/6637/199746/10250/6635/6634/10914/10569/6432/8683/6431/9775/10189/6430/51362/55110/9295/22794/81608/6427/4686/9785/8189/51692/11051/11338/6426/4116/1477/23283/10978/79869/22916/65109/9939/1479/51585/6429/1478/6428/55339/6628/6636/8106 47 Vesicular_stomatitis_Indiana_virus R-HSA-168325 Viral Messenger RNA Synthesis 38/771 43/10654 1.32098799979874e-38 1.4674737977962239e-037 7.544569295359142e-38 2962/23165/9972/348995/4928/2963/79023/5437/81929/57122/5441/5434/23636/5440/5903/23225/8021/5438/10762/5431/7175/6396/129401/23511/5435/9631/5433/53371/5439/5430/5432/55746/5436/8480/23279/4927/9688/79902 38 Vesicular_stomatitis_Indiana_virus R-HSA-5619084 ABC transporter disorders 50/771 77/10654 1.4257555304379515e-38 1.5683310834817467e-37 8.063096291847239e-38 5716/9491/5715/23198/1080/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/79139/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Vesicular_stomatitis_Indiana_virus R-HSA-5621481 C-type lectin receptors (CLRs) 66/771 142/10654 5.582595288220661e-38 6.0812348673627e-37 3.1264815717372737e-37 5716/9491/5715/8454/23198/6500/5718/7311/5711/5971/5689/8945/5701/5688/1387/143471/5706/5687/5705/5684/23291/10197/5720/5685/5683/5698/5708/5692/5686/4790/5713/3845/2033/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/7321/5707/9020/5702/5970/4792/5062/5693/9040/5721/5696/5719/10768/5691/4791/5714/5690/6714/7314/5704/6233/5717/9861 66 Vesicular_stomatitis_Indiana_virus R-HSA-5687128 MAPK6/MAPK4 signaling 53/771 89/10654 5.714418195146121e-38 6.164978091301873e-37 3.169535598117484e-37 5716/9491/5715/23198/7514/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5062/983/5693/5597/5721/5696/5719/5691/5714/5690/4609/7314/5704/6233/5717/9861 53 Vesicular_stomatitis_Indiana_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 64/771 134/10654 9.331030401415572e-38 9.970872486084068e-37 5.12622021050199e-37 5716/9491/5715/8454/7409/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/23291/6464/10197/5720/5685/5683/5698/5708/5692/5686/4790/5713/3845/5599/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/7321/5707/5702/5970/4792/5062/5693/5721/5696/5719/10768/5691/5714/5690/6654/7314/5704/6233/2885/5717/9861 64 Vesicular_stomatitis_Indiana_virus R-HSA-4086400 PCP/CE pathway 53/771 92/10654 6.384714513531022e-37 6.758160079416799e-36 3.474502039141013e-36 5716/9491/5715/1857/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/144165/10197/5720/5685/5683/64750/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/1856/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/1855/5717/9861 53 Vesicular_stomatitis_Indiana_virus R-HSA-5688426 Deubiquitination 93/771 297/10654 4.0417141202344604e-36 4.238133871872023e-35 2.1789073663438116e-35 5716/9491/81847/5715/672/23198/1080/5718/9804/330/7311/5711/3091/5689/5701/5688/9097/143471/329/5706/5687/5705/7187/5684/6502/55031/10197/4088/7706/5720/5685/23770/7040/5683/64750/5698/5708/5887/580/7186/5692/5686/5713/7416/324/2033/5682/7316/10213/5728/5709/1540/29761/5694/5699/993/5695/8312/79155/80351/7874/5710/890/5700/122706/7321/5707/5702/991/51377/7157/4792/8900/8658/983/9958/5693/8313/5721/11047/5696/5719/5691/4738/5886/5714/5690/4609/7314/5704/6233/5717/9861 93 Vesicular_stomatitis_Indiana_virus R-HSA-69275 G2/M Transition 75/771 196/10654 6.619000209621191e-36 6.876405773328683e-35 3.5352944589399735e-35 5716/9491/5715/8454/23198/6500/7514/5519/5718/1017/7311/5711/5689/8945/5701/23194/5688/143471/5706/5518/5687/5705/5684/5347/23291/10197/5720/5685/5683/5698/5708/5692/5686/5713/2033/5682/7316/10213/5709/728642/5694/5699/9978/51512/993/5695/5710/890/5700/122706/5707/5702/7157/5108/8900/983/5693/84962/1026/5721/5696/5719/6790/5691/5714/5690/4751/7314/5577/5704/6233/5515/5717/9861/5516 75 Vesicular_stomatitis_Indiana_virus R-HSA-1257604 PIP3 activates AKT signaling 87/771 264/10654 1.025440914142537e-35 1.0555456015302078e-34 5.426766015935397e-35 5716/9491/81847/5715/7409/23198/3082/5519/5718/7311/5711/5689/2932/5701/5688/143471/3643/5706/5159/5518/5155/5687/5705/5684/1956/10197/5720/5685/5683/5698/5708/8726/5692/5686/5713/5528/2100/2549/5682/57332/7316/10213/5728/5709/5694/5699/5525/1950/5695/5529/80351/7874/5710/5700/122706/5707/3630/5702/2146/3065/5526/7157/1457/4233/8658/5693/1026/5721/5696/4734/6045/5719/5691/5714/5690/6714/7314/5704/6233/5527/2885/11060/5515/5717/1027/9861/5516 87 Vesicular_stomatitis_Indiana_virus R-HSA-72187 mRNA 3'-end processing 42/771 58/10654 1.1534842309067409e-35 1.1765539155248757e-34 6.048893383128173e-35 10921/10898/29894/53981/199746/10250/10914/10569/6432/8683/6431/9775/10189/6430/51362/55110/9295/22794/81608/6427/4686/9785/8189/51692/11051/11338/6426/4116/1477/23283/10978/79869/22916/65109/9939/1479/51585/6429/1478/6428/55339/8106 42 Vesicular_stomatitis_Indiana_virus R-HSA-453274 Mitotic G2-G2/M phases 75/771 198/10654 1.502321165414398e-35 1.51856247531077e-34 7.807226160712093e-35 5716/9491/5715/8454/23198/6500/7514/5519/5718/1017/7311/5711/5689/8945/5701/23194/5688/143471/5706/5518/5687/5705/5684/5347/23291/10197/5720/5685/5683/5698/5708/5692/5686/5713/2033/5682/7316/10213/5709/728642/5694/5699/9978/51512/993/5695/5710/890/5700/122706/5707/5702/7157/5108/8900/983/5693/84962/1026/5721/5696/5719/6790/5691/5714/5690/4751/7314/5577/5704/6233/5515/5717/9861/5516 75 Vesicular_stomatitis_Indiana_virus R-HSA-5689880 Ub-specific processing proteases 79/771 220/10654 1.7613922358590542e-35 1.764537579137374e-34 9.071832192206408e-35 5716/9491/81847/5715/23198/1080/5718/9804/330/7311/5711/3091/5689/5701/5688/9097/143471/329/5706/5687/5705/5684/6502/55031/10197/4088/5720/5685/23770/5683/64750/5698/5708/7186/5692/5686/5713/7416/5682/7316/10213/5728/5709/1540/29761/5694/5699/993/5695/8312/80351/7874/5710/890/5700/122706/5707/5702/991/7157/4792/8900/8658/9958/5693/8313/5721/11047/5696/5719/5691/5714/5690/4609/7314/5704/6233/5717/9861 79 Vesicular_stomatitis_Indiana_virus R-HSA-5689603 UCH proteinases 54/771 102/10654 5.483799604176338e-35 5.44497624414677e-34 2.79936859160562e-34 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/7040/5683/5698/5708/580/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/51377/9958/5693/5721/11047/5696/5719/5691/4738/5714/5690/7314/5704/6233/5717/9861 54 Vesicular_stomatitis_Indiana_virus R-HSA-202403 TCR signaling 58/771 119/10654 6.579616337594149e-35 6.475727658579505e-34 3.3292980175453316e-34 5716/9491/5715/8454/23198/6500/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/23291/10197/5720/5685/5683/5698/5708/5692/5686/4790/5713/5682/7316/10213/5728/5709/5694/5699/5695/5710/5700/122706/7321/5707/5702/5970/4792/5062/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 58 Vesicular_stomatitis_Indiana_virus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 35/771 41/10654 1.7339342186698677e-34 1.691716689867471e-33 8.697445783350915e-34 10898/29894/23165/53981/9972/348995/4928/79023/81929/57122/23636/5903/23225/8021/10189/10762/7175/6396/129401/23511/81608/4686/9631/8189/10482/51692/53371/55746/22916/8480/55339/23279/4927/9688/79902 35 Vesicular_stomatitis_Indiana_virus R-HSA-6807070 PTEN Regulation 62/771 140/10654 3.4364212524643815e-34 3.323848832125031e-33 1.708855577450527e-33 5716/9491/81847/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/8726/5692/5686/5713/5682/57332/7316/10213/5728/5709/5694/5699/5695/80351/7874/5710/5700/122706/5707/5702/2146/3065/7157/1457/8658/5693/5721/5696/4734/6045/5719/5691/5714/5690/7314/5704/6233/11060/5717/9861 62 Vesicular_stomatitis_Indiana_virus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 35/771 42/10654 9.702416387554284e-34 9.304368535757185e-33 4.783557517210749e-33 10898/29894/23165/53981/9972/348995/4928/79023/81929/57122/23636/5903/23225/8021/10189/10762/7175/6396/129401/23511/81608/4686/9631/8189/10482/51692/53371/55746/22916/8480/55339/23279/4927/9688/79902 35 Vesicular_stomatitis_Indiana_virus R-HSA-1236974 ER-Phagosome pathway 48/771 83/10654 1.2345262781960486e-33 1.1738461729965818e-32 6.0349723501466075e-33 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Vesicular_stomatitis_Indiana_virus R-HSA-69481 G2/M Checkpoints 67/771 168/10654 1.899772326232059e-33 1.7912139075902271e-32 9.208980404910822e-33 5716/9491/5715/672/23198/4998/5718/1017/7158/2810/7311/6119/5711/6118/5689/5701/5688/143471/5706/472/5687/5705/5684/10197/5720/5685/5683/5698/5708/580/6117/5692/5686/5713/990/5682/7316/84126/10213/5709/5694/5699/51512/993/5695/5710/5700/122706/5707/5702/7157/983/5693/5721/5696/5719/5691/5714/5690/8924/4171/51588/7314/5704/6233/5717/9861 67 Vesicular_stomatitis_Indiana_virus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 91/771 309/10654 5.392906017228199e-33 5.042367126108366e-32 2.592379383720222e-32 5716/9491/5715/8454/23198/6500/5718/25793/51343/7311/5711/5689/8945/5701/23194/5688/143471/5706/5687/26270/5705/5684/6502/23291/8065/10197/5720/5685/11065/5683/64750/5698/5708/9690/5692/8881/5686/8452/9666/5713/29882/57520/5682/7316/10213/5709/246184/5694/5699/9978/5695/7319/5710/5700/10422/122706/7321/5707/7428/5702/991/8453/11059/83737/51529/5693/9040/5721/7324/5696/4734/5719/10075/64682/7337/5691/29945/10393/8697/5714/5690/8924/9820/7314/996/5704/6233/51434/5717/51433/9861 91 Vesicular_stomatitis_Indiana_virus R-HSA-9006925 Intracellular signaling by second messengers 90/771 305/10654 1.0447909707304261e-32 9.688061728591225e-32 4.980821678645268e-32 5716/9491/81847/5715/7409/23198/3082/5519/5718/7311/5711/5689/2932/5701/5688/143471/3643/5706/3838/5159/5518/5155/5687/5705/5684/1956/10197/5720/5685/5683/5698/5708/8726/5692/5686/5713/5528/2100/2549/5682/57332/7316/10213/5728/5709/5694/5699/5525/1950/5695/5529/80351/7874/5710/5700/122706/5707/3630/5702/2146/3065/5526/7157/1457/4233/8658/5693/1026/5721/5696/4734/6045/5719/10768/5691/5714/5690/6714/7314/5577/5704/6233/5527/2885/11060/5515/5717/1027/9861/5516 90 Vesicular_stomatitis_Indiana_virus R-HSA-5357801 Programmed Cell Death 68/771 181/10654 5.018639632550923e-32 4.615503006329619e-31 2.3729202058998323e-31 5716/9491/5715/23198/4000/5718/1828/330/2810/7311/5711/5689/7161/11035/5701/5688/143471/329/3837/5706/5687/5705/5684/10197/999/5720/5685/5683/5698/5708/100506658/7186/5692/5686/5713/324/5599/7159/5682/7316/1499/10213/5709/5694/5699/4137/5695/5710/5700/122706/5707/5702/6774/7157/5062/5693/5721/5696/5719/3836/5691/5714/5690/7314/5704/6233/5717/9861 68 Vesicular_stomatitis_Indiana_virus R-HSA-5684996 MAPK1/MAPK3 signaling 81/771 255/10654 5.551882545971833e-32 5.064400176081623e-31 2.6037070048716856e-31 5716/9491/5715/23198/3082/5519/5718/7311/5711/5689/5701/5688/143471/5706/5159/5518/5155/5687/5705/5684/3717/6464/1956/10197/5720/5685/399473/5683/5698/5708/5692/5686/8452/5713/3845/5528/5682/7316/10213/5709/5694/5699/9978/5525/1950/5695/5529/5710/200734/5700/122706/4763/5707/7297/5702/5526/4233/983/5693/5721/5696/3718/5719/5691/5714/5690/5245/6714/6654/7314/5704/6233/11221/5527/2885/161742/5515/5717/9861/3716/5516 81 Vesicular_stomatitis_Indiana_virus R-HSA-382556 ABC-family proteins mediated transport 51/771 103/10654 3.116155766233965e-31 2.8196183626729908e-30 1.4496208488083301e-30 5716/9491/5715/23198/1080/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/1965/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/79139/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 51 Vesicular_stomatitis_Indiana_virus R-HSA-9607240 FLT3 Signaling 82/771 267/10654 3.393069139652593e-31 3.045618859752168e-30 1.565812116656523e-30 5716/9491/5715/23198/3082/5519/5718/7311/5711/5689/5701/5688/143471/5706/5159/5518/5155/5687/5705/5684/3717/6464/1956/10197/5720/5685/399473/5683/5698/5708/5692/5686/8452/5713/3845/6776/5528/2549/5682/6777/7316/10213/5709/5694/5699/9978/5525/1950/5695/5529/5710/200734/5700/122706/4763/5707/5702/5526/4233/5693/5721/5696/3718/5719/5691/5714/5690/5245/6714/6654/7314/5704/6233/11221/5527/2885/161742/5515/5717/9861/3716/5516 82 Vesicular_stomatitis_Indiana_virus R-HSA-5673001 RAF/MAP kinase cascade 79/771 249/10654 3.664528901244427e-31 3.2631757358700376e-30 1.6776623541202557e-30 5716/9491/5715/23198/3082/5519/5718/7311/5711/5689/5701/5688/143471/5706/5159/5518/5155/5687/5705/5684/3717/6464/1956/10197/5720/5685/399473/5683/5698/5708/5692/5686/8452/5713/3845/5528/5682/7316/10213/5709/5694/5699/9978/5525/1950/5695/5529/5710/200734/5700/122706/4763/5707/5702/5526/4233/5693/5721/5696/3718/5719/5691/5714/5690/5245/6714/6654/7314/5704/6233/11221/5527/2885/161742/5515/5717/9861/3716/5516 79 Vesicular_stomatitis_Indiana_virus R-HSA-177243 Interactions of Rev with host cellular proteins 31/771 36/10654 6.666869205985667e-31 5.8899427158393056e-30 3.0281345419644805e-30 7514/23165/5905/9972/348995/4928/3837/79023/81929/57122/23636/5903/23225/8021/10762/7175/6396/129401/23511/9631/1104/53371/5902/5901/55746/8480/23279/4927/9688/4869/79902 31 Vesicular_stomatitis_Indiana_virus R-HSA-8951664 Neddylation 76/771 234/10654 9.168487754533102e-31 8.036752547332923e-30 4.1318513893784056e-30 5716/9491/5715/8454/23198/6500/5718/25793/7311/5711/3091/5689/54165/8945/5701/23194/5688/143471/5706/5687/26270/5705/2034/5684/6502/23291/8065/10197/5720/5685/5683/55832/5698/5708/5692/5686/8452/23363/5713/8450/5682/64344/7316/10213/5709/5694/5699/9978/5695/5710/5700/122706/7321/5707/10987/7428/5702/8453/5693/9040/5721/5696/5719/5691/4738/5714/5690/9820/7314/5704/6233/10537/8451/5717/10980/9861 76 Vesicular_stomatitis_Indiana_virus R-HSA-109581 Apoptosis 66/771 178/10654 1.0533161597719906e-30 9.161401017551732e-30 4.710055124888216e-30 5716/9491/5715/23198/4000/5718/1828/2810/7311/5711/5689/7161/5701/5688/143471/329/3837/5706/5687/5705/5684/10197/999/5720/5685/5683/5698/5708/100506658/7186/5692/5686/5713/324/5599/7159/5682/7316/1499/10213/5709/5694/5699/4137/5695/5710/5700/122706/5707/5702/6774/7157/5062/5693/5721/5696/5719/3836/5691/5714/5690/7314/5704/6233/5717/9861 66 Vesicular_stomatitis_Indiana_virus R-HSA-5683057 MAPK family signaling cascades 85/771 294/10654 3.4564230183874006e-30 2.9831589435620484e-29 1.5337002543127898e-29 5716/9491/5715/23198/3082/7514/5519/5718/7311/5711/5689/5701/5688/143471/5706/5159/5518/5155/5687/5705/5684/3717/6464/1956/10197/5720/5685/399473/5683/5698/5708/5692/5686/8452/5713/3845/5528/5682/7316/10213/5709/5694/5699/9978/5525/1950/5695/5529/5710/200734/5700/122706/4763/5707/7297/5702/5526/5062/4233/983/5693/5597/5721/5696/3718/5719/5691/5714/5690/5245/6714/6654/4609/7314/5704/6233/11221/5527/2885/161742/5515/5717/9861/3716/5516 85 Vesicular_stomatitis_Indiana_virus R-HSA-449147 Signaling by Interleukins 109/771 461/10654 4.11663331822878e-30 3.5258493000402225e-29 1.8127079617431675e-29 5716/9491/5715/8454/7409/23198/6500/3082/7124/5519/5718/7311/5711/3091/5689/5777/8945/5701/5688/143471/3575/5706/5518/5687/5705/5684/3717/9987/351/23291/6464/10197/4088/5720/6778/5685/7040/5683/5698/5708/5692/5686/4790/5713/4843/6627/5599/6776/5528/5606/3688/5682/6777/1436/7316/595/10213/5709/5694/5699/9978/3312/5695/79155/5771/5710/6773/5700/3458/3181/122706/5707/7297/5702/3185/5608/27178/6774/7157/1435/5970/4792/5062/5693/1026/6775/5721/5696/3718/5719/4793/5691/7422/7133/4791/5714/5690/6772/6654/4609/7314/5704/6233/2885/5515/5717/9861/3716/5516 109 Vesicular_stomatitis_Indiana_virus R-HSA-195721 Signaling by WNT 90/771 331/10654 1.0304325947075989e-29 8.758677055014591e-29 4.5030068732038617e-29 5716/9491/81847/5715/8454/1857/23198/6500/7514/5519/23072/5718/79577/7311/5711/5689/2932/8945/5701/5688/1387/143471/5706/5518/5687/5705/5684/144165/10197/5720/5685/5683/64750/5698/5708/5692/5686/8452/5713/324/3845/2033/5528/5682/7316/1499/10213/5709/5694/5699/9978/5525/5695/8312/864/5529/80351/5710/5700/139285/122706/5707/5702/3065/1856/89780/5526/1457/8658/5693/8313/5721/5696/1452/5719/5691/5714/5690/4609/7314/59349/5704/6233/5527/1855/123169/5515/5717/9861/5516 90 Vesicular_stomatitis_Indiana_virus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 25/771 25/10654 2.1378413119474504e-29 1.803502219552661e-28 9.272157015806909e-29 701/7311/9184/25906/11065/8881/29882/119504/7316/246184/7321/991/4085/51529/7324/64682/29945/10393/8697/4751/7314/996/6233/51434/51433 25 Vesicular_stomatitis_Indiana_virus R-HSA-1236975 Antigen processing-Cross presentation 48/771 99/10654 6.418998358463816e-29 5.3747135508928365e-28 2.7632451692365845e-28 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Vesicular_stomatitis_Indiana_virus R-HSA-165054 Rev-mediated nuclear export of HIV RNA 29/771 34/10654 1.0101273480717836e-28 8.395280626196602e-28 4.316177674411988e-28 7514/23165/5905/9972/348995/4928/79023/81929/57122/23636/5903/23225/8021/10762/7175/6396/129401/23511/9631/1104/53371/5902/5901/55746/8480/23279/4927/9688/79902 29 Vesicular_stomatitis_Indiana_virus R-HSA-168253 Host Interactions with Influenza Factors 32/771 42/10654 1.2783850946862305e-28 1.0546677031161402e-27 5.4222525687929905e-28 10898/23165/9972/348995/4928/3837/79023/3838/81929/57122/5610/23636/5903/23225/8021/7040/10762/7175/6396/129401/23511/9631/53371/55746/3836/8480/23279/4927/9688/8106/3841/79902 32 Vesicular_stomatitis_Indiana_virus R-HSA-162599 Late Phase of HIV Life Cycle 56/771 139/10654 2.3109884687927645e-28 1.892648950354366e-27 9.730477763337956e-28 2962/404672/7514/1025/23165/7311/5905/9972/348995/4928/2963/79023/5437/81929/57122/5441/5434/23636/5440/5903/55048/23225/8021/5438/7251/10762/5431/128866/7175/6396/129401/23511/5435/4686/9631/7316/5433/1104/53371/5439/2959/5430/5902/5901/5432/55746/22916/5436/8480/23279/4927/9688/8148/7314/6233/79902 56 Vesicular_stomatitis_Indiana_virus R-HSA-168276 NS1 Mediated Effects on Host Pathways 31/771 40/10654 3.656458712696047e-28 2.9728599098876554e-27 1.5284053200285536e-27 10898/23165/9972/348995/4928/3837/79023/3838/81929/57122/5610/23636/5903/23225/8021/10762/7175/6396/129401/23511/9631/53371/55746/3836/8480/23279/4927/9688/8106/3841/79902 31 Vesicular_stomatitis_Indiana_virus R-HSA-983169 Class I MHC mediated antigen processing & presentation 93/771 371/10654 9.612967231042815e-28 7.759531822467653e-27 3.9893268024320056e-27 5716/9491/5715/8454/23198/6500/5718/25793/51343/7311/5711/5689/8945/5701/23194/5688/143471/5706/5687/26270/5705/5684/6502/23291/8065/10197/5720/5685/11065/5683/64750/3309/5698/5708/9690/5692/8881/5686/8452/9666/5713/29882/57520/6396/5682/7316/10213/5709/246184/5694/5699/9978/5695/7319/5710/5700/10422/122706/7321/5707/7428/5702/991/8453/11059/83737/51529/5693/9040/5721/7324/5696/4734/5719/10075/64682/7337/5691/29945/10393/8697/5714/5690/8924/9820/7314/996/5704/6233/51434/5717/51433/9861 93 Vesicular_stomatitis_Indiana_virus R-HSA-180746 Nuclear import of Rev protein 28/771 33/10654 1.2321629501458972e-27 9.874905929026405e-27 5.0768819299244496e-27 23165/9972/348995/4928/3837/79023/81929/57122/23636/5903/23225/8021/10762/7175/6396/129401/23511/9631/1104/53371/5901/55746/8480/23279/4927/9688/4869/79902 28 Vesicular_stomatitis_Indiana_virus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 61/771 171/10654 2.3057949997517146e-27 1.8348241061854067e-26 9.433188950085403e-27 5716/9491/5715/23198/10921/5718/7311/5711/5689/5701/5688/23053/143471/5706/6123/5687/5705/5684/10197/5720/5685/9775/5683/5698/5708/5692/5686/5713/55110/22794/5682/4686/7316/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/4116/8453/22916/5693/65109/5721/9939/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 61 Vesicular_stomatitis_Indiana_virus R-HSA-1169408 ISG15 antiviral mechanism 40/771 72/10654 2.8460326436455423e-27 2.2487666381480975e-26 1.1561348322592716e-26 23165/7311/9972/348995/4928/3837/79023/3838/81929/57122/5610/23636/5903/23225/7706/5300/8021/9775/10762/7175/6396/129401/23511/9631/7316/53371/55746/7324/4734/3836/8480/6772/23279/4927/9688/7314/6233/3841/79902/3716 40 Vesicular_stomatitis_Indiana_virus R-HSA-162587 HIV Life Cycle 57/771 152/10654 6.264635208667566e-27 4.9153291637237823e-26 2.5270666870444068e-26 2962/404672/7514/1025/23165/7311/5905/9972/348995/4928/2963/79023/5437/81929/57122/5441/5434/23636/5440/5903/55048/23225/8021/5438/7251/10762/5431/128866/7175/6396/129401/23511/5435/4686/9631/7316/5433/1104/53371/5439/2959/5430/5902/5901/5432/55746/22916/5436/3836/8480/23279/4927/9688/8148/7314/6233/79902 57 Vesicular_stomatitis_Indiana_virus R-HSA-159227 Transport of the SLBP independent Mature mRNA 28/771 34/10654 6.510863955059958e-27 5.0730481649842177e-26 2.6081531048047204e-26 23165/9972/348995/4928/79023/81929/57122/23636/5903/23225/8021/10189/10762/7175/6396/129401/23511/4686/9631/10482/53371/55746/22916/8480/23279/4927/9688/79902 28 Vesicular_stomatitis_Indiana_virus R-HSA-157118 Signaling by NOTCH 71/771 235/10654 1.3447084786758248e-26 1.0405261469477762e-25 5.349548067617801e-26 5716/9491/5715/8454/6500/22938/5718/7311/5711/3091/5689/5701/5688/1387/5706/5687/5705/5684/10402/1956/10197/4088/5720/5685/5683/5698/5708/5692/5686/5713/79885/2033/5682/4855/7316/595/10213/5709/5694/5699/9978/1950/5695/55869/5710/5700/5707/5702/3065/8650/7157/83737/5693/5721/6484/4904/5696/5719/10959/5691/5714/5690/2683/6772/4609/7314/5704/6233/11060/5717/9861 71 Vesicular_stomatitis_Indiana_virus R-HSA-191859 snRNP Assembly 34/771 53/10654 2.668145511091983e-26 2.0365029003028606e-25 1.0470059005215947e-25 23165/6637/9972/348995/4928/79023/6635/81929/57122/6634/23636/6606/5903/6633/23225/8021/6632/10762/7175/6396/129401/23511/4686/9631/53371/55746/22916/8480/23279/4927/6628/9688/6636/79902 34 Vesicular_stomatitis_Indiana_virus R-HSA-194441 Metabolism of non-coding RNA 34/771 53/10654 2.668145511091983e-26 2.0365029003028606e-25 1.0470059005215947e-25 23165/6637/9972/348995/4928/79023/6635/81929/57122/6634/23636/6606/5903/6633/23225/8021/6632/10762/7175/6396/129401/23511/4686/9631/53371/55746/22916/8480/23279/4927/6628/9688/6636/79902 34 Vesicular_stomatitis_Indiana_virus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 28/771 35/10654 3.0356476197032316e-26 2.3013490738560985e-25 1.1831684890450718e-25 23165/9972/348995/4928/79023/81929/57122/23636/5903/23225/8021/10189/10762/7175/6396/129401/23511/4686/9631/10482/53371/55746/22916/8480/23279/4927/9688/79902 28 Vesicular_stomatitis_Indiana_virus R-HSA-3858494 Beta-catenin independent WNT signaling 55/771 146/10654 3.909625441860993e-26 2.9440266750121035e-25 1.5135815910560397e-25 5716/9491/5715/1857/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/144165/10197/5720/5685/5683/64750/5698/5708/5692/5686/5713/3845/5682/7316/1499/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/1856/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/1855/5717/9861 55 Vesicular_stomatitis_Indiana_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 41/771 80/10654 4.4338709732819566e-26 3.316535488014904e-25 1.705095644462114e-25 23165/7311/9972/348995/4928/3837/79023/3838/81929/57122/5610/23636/8638/5903/23225/7706/5300/8021/9775/10762/7175/6396/129401/23511/9631/7316/53371/55746/7324/4734/3836/8480/6772/23279/4927/9688/7314/6233/3841/79902/3716 41 Vesicular_stomatitis_Indiana_virus R-HSA-69618 Mitotic Spindle Checkpoint 48/771 112/10654 6.738704908452518e-26 5.00717013727399e-25 2.5742839245953158e-25 701/7514/5519/9184/5905/348995/4928/79023/5518/25906/81929/57122/5903/5347/11065/8881/29882/6396/119504/5528/246184/25936/5525/80776/5501/5529/25909/7321/991/5526/4085/51529/55746/7324/64682/29945/10393/80152/8697/9212/23279/996/5527/51434/5515/51433/79902/5516 48 Vesicular_stomatitis_Indiana_virus R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 26/771 31/10654 1.7975738638238858e-25 1.3182208334708495e-24 6.777230666498037e-25 23165/9972/348995/4928/3837/79023/81929/57122/23636/5903/23225/8021/10762/7175/6396/129401/23511/9631/53371/55746/3836/8480/23279/4927/9688/79902 26 Vesicular_stomatitis_Indiana_virus R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 26/771 31/10654 1.7975738638238858e-25 1.3182208334708495e-24 6.777230666498037e-25 7514/23165/9972/348995/4928/79023/81929/57122/23636/5903/23225/8021/10762/7175/6396/129401/23511/9631/53371/5901/55746/8480/23279/4927/9688/79902 26 Vesicular_stomatitis_Indiana_virus R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs 51/771 130/10654 2.830990906199363e-25 2.0625790888023928e-24 1.0604121781252572e-24 5716/9491/5715/23198/5718/7311/5711/5689/7161/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/83737/5693/5721/5696/5719/5691/10413/5714/5690/7314/5704/6233/5717/9861 51 Vesicular_stomatitis_Indiana_virus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 22/771 23/10654 1.3165099380487068e-24 9.529833228971928e-24 4.89947331783152e-24 7311/25906/11065/8881/29882/119504/7316/246184/7321/991/51529/983/7324/64682/29945/10393/8697/7314/996/6233/51434/51433 22 Vesicular_stomatitis_Indiana_virus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 28/771 38/10654 1.7303523792833172e-24 1.244522672792232e-23 6.398334034057071e-24 23165/9972/348995/4928/79023/81929/57122/23636/5903/23225/8021/10762/7175/6396/129401/23511/9631/53371/7428/55746/7329/8480/51588/23279/4927/9688/8554/79902 28 Vesicular_stomatitis_Indiana_virus R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 26/771 33/10654 3.9300767331701136e-24 2.8086280857432276e-23 1.4439705328710845e-23 7514/23165/9972/348995/4928/79023/81929/57122/23636/5903/23225/8021/10762/7175/6396/129401/23511/9631/53371/5901/55746/8480/23279/4927/9688/79902 26 Vesicular_stomatitis_Indiana_virus R-HSA-75067 Processing of Capped Intronless Pre-mRNA 24/771 28/10654 4.71067680724121e-24 3.345176821344707e-23 1.7198207131033868e-23 10898/29894/53981/6637/6635/6634/10914/81608/4686/8189/51692/11051/1477/23283/10978/79869/22916/1479/51585/1478/55339/6628/6636/8106 24 Vesicular_stomatitis_Indiana_virus R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 20/771 20/10654 1.2320974759064398e-23 8.64008354979391e-23 4.442035636820586e-23 701/9184/25906/11065/8881/29882/119504/246184/7321/991/4085/51529/7324/64682/29945/10393/8697/996/51434/51433 20 Vesicular_stomatitis_Indiana_virus R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 20/771 20/10654 1.2320974759064398e-23 8.64008354979391e-23 4.442035636820586e-23 701/9184/25906/11065/8881/29882/119504/246184/7321/991/4085/51529/7324/64682/29945/10393/8697/996/51434/51433 20 Vesicular_stomatitis_Indiana_virus R-HSA-4085377 SUMOylation of SUMOylation proteins 26/771 34/10654 1.557544093374853e-23 1.0854437719047113e-22 5.580478346972341e-23 23165/9972/348995/4928/79023/81929/57122/23636/5903/23225/8021/10762/7175/6396/129401/23511/9631/53371/55746/7329/8480/51588/23279/4927/9688/79902 26 Vesicular_stomatitis_Indiana_virus R-HSA-376176 Signaling by ROBO receptors 64/771 218/10654 2.7099809556575456e-23 1.876912735955411e-22 9.649574812867674e-23 5716/9491/5715/23198/10921/5718/7311/5711/5689/5701/5688/23053/143471/5706/6123/5687/5705/5684/10197/5720/5685/9775/5683/5698/5708/5692/5686/5713/55110/22794/5682/4686/7316/10213/5709/5694/5699/9978/5695/5710/5700/122706/5707/5702/4116/8453/5062/22916/5693/65109/5721/9939/5696/5719/5691/5714/5690/6714/6654/7314/5704/6233/5717/9861 64 Vesicular_stomatitis_Indiana_virus R-HSA-168254 Influenza Infection 53/771 155/10654 6.703006307844961e-23 4.61397121313009e-22 2.3721326811101317e-22 2962/10898/7514/23165/7311/9972/348995/4928/2963/3837/79023/5437/3838/6123/81929/57122/5441/5610/5434/23636/5440/5903/23225/2926/8021/7040/5438/10762/5431/7175/6396/129401/23511/5435/9631/5433/53371/3843/5439/5430/5901/5432/55746/5436/3836/8480/23279/4927/9688/6233/8106/3841/79902 53 Vesicular_stomatitis_Indiana_virus R-HSA-4615885 SUMOylation of DNA replication proteins 29/771 45/10654 1.0880655769633564e-22 7.443960837517597e-22 3.827085598048263e-22 23165/5905/9972/348995/4928/79023/81929/57122/23636/5903/23225/8021/10762/7175/6396/129401/23511/9631/53371/55746/7329/6790/8480/9212/51588/23279/4927/9688/79902 29 Vesicular_stomatitis_Indiana_virus R-HSA-180910 Vpr-mediated nuclear import of PICs 25/771 33/10654 1.6972821771754479e-22 1.1541518804793045e-21 5.9337201473183125e-22 23165/9972/348995/4928/79023/81929/57122/23636/5903/23225/8021/10762/7175/6396/129401/23511/9631/53371/55746/3836/8480/23279/4927/9688/79902 25 Vesicular_stomatitis_Indiana_virus R-HSA-77595 Processing of Intronless Pre-mRNAs 19/771 19/10654 1.7424676404607655e-22 1.1777401762632401e-21 6.054992181182623e-22 10898/29894/53981/10914/81608/4686/8189/51692/11051/1477/23283/10978/79869/22916/1479/51585/1478/55339/8106 19 Vesicular_stomatitis_Indiana_virus R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 24/771 31/10654 4.906338118807429e-22 3.276732957917819e-21 1.68463238665819e-21 23165/9972/348995/4928/79023/81929/57122/23636/5903/23225/8021/10762/7175/6396/129401/23511/9631/53371/55746/8480/23279/4927/9688/79902 24 Vesicular_stomatitis_Indiana_virus R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 24/771 31/10654 4.906338118807429e-22 3.276732957917819e-21 1.68463238665819e-21 23165/9972/348995/4928/79023/81929/57122/23636/5903/23225/8021/10762/7175/6396/129401/23511/9631/53371/55746/8480/23279/4927/9688/79902 24 Vesicular_stomatitis_Indiana_virus R-HSA-4570464 SUMOylation of RNA binding proteins 29/771 47/10654 6.68455504260585e-22 4.437911691008144e-21 2.281617043505454e-21 23165/9972/348995/4928/79023/81929/57122/23636/5903/23225/8021/3183/10762/7175/6396/129401/23511/9631/57332/53371/3190/55746/7329/6045/8480/23279/4927/9688/79902 29 Vesicular_stomatitis_Indiana_virus R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 25/771 35/10654 1.9515491662734143e-21 1.2880224497404534e-20 6.6219748799865706e-21 23165/9972/348995/4928/79023/81929/57122/23636/5903/23225/8021/10762/7175/6396/129401/23511/9631/53371/55746/983/8480/23279/4927/9688/79902 25 Vesicular_stomatitis_Indiana_virus R-HSA-176033 Interactions of Vpr with host cellular proteins 25/771 36/10654 5.9559472970927064e-21 3.9079373493204777e-20 2.009146887538814e-20 23165/9972/348995/4928/79023/81929/57122/23636/5903/23225/8021/10762/7175/6396/129401/23511/9631/53371/55746/3836/8480/23279/4927/9688/79902 25 Vesicular_stomatitis_Indiana_virus R-HSA-8878171 Transcriptional regulation by RUNX1 63/771 239/10654 3.145127283159424e-20 2.051646983549345e-19 1.0547917693827199e-19 5716/9491/5715/23198/5718/7311/5711/5689/7161/5701/5688/1387/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/100506658/5692/5686/5713/2033/5682/57332/7316/595/10213/5709/3276/5694/5699/5695/8312/5710/5700/3458/122706/5707/5702/3065/1457/83737/5693/5721/5696/6045/5719/5691/10413/5714/5690/6714/7314/5704/6233/5717/9861 63 Vesicular_stomatitis_Indiana_virus R-HSA-6803529 FGFR2 alternative splicing 21/771 26/10654 4.039649253701727e-20 2.6199343714759176e-19 1.3469594104219937e-19 2962/3178/2963/5437/5441/5434/5440/4670/5438/5431/5435/4686/5433/5439/3185/5430/5432/22916/5436/5725/3187 21 Vesicular_stomatitis_Indiana_virus R-HSA-5654738 Signaling by FGFR2 34/771 73/10654 4.115031731790227e-20 2.6534859787750776e-19 1.3642089467761915e-19 2962/7311/3178/2963/5437/5518/5441/5434/5440/4670/6464/5438/5431/3845/2549/5435/4686/7316/5433/5439/3185/5430/5432/22916/5436/5725/6714/6654/7314/6233/2885/3187/5515/5516 34 Vesicular_stomatitis_Indiana_virus R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 18/771 19/10654 4.362648396494874e-20 2.781188352765482e-19 1.4298632304301383e-19 51343/25906/11065/8881/29882/119504/246184/7321/991/51529/7324/64682/29945/10393/8697/996/51434/51433 18 Vesicular_stomatitis_Indiana_virus R-HSA-176412 Phosphorylation of the APC/C 18/771 19/10654 4.362648396494874e-20 2.781188352765482e-19 1.4298632304301383e-19 25906/5347/11065/8881/29882/119504/246184/7321/51529/983/7324/64682/29945/10393/8697/996/51434/51433 18 Vesicular_stomatitis_Indiana_virus R-HSA-6784531 tRNA processing in the nucleus 30/771 57/10654 7.643474954755185e-20 4.845185818777016e-19 2.491004623970171e-19 10898/29894/23165/9972/348995/4928/79023/81929/57122/23636/5903/23225/8021/10762/7175/6396/129401/23511/9631/53371/5901/55746/10978/1478/8480/10556/23279/4927/9688/79902 30 Vesicular_stomatitis_Indiana_virus R-HSA-168255 Influenza Life Cycle 47/771 144/10654 1.7666021463264261e-19 1.1135548360551965e-18 5.725002816007579e-19 2962/7514/23165/7311/9972/348995/4928/2963/3837/79023/5437/6123/81929/57122/5441/5434/23636/5440/5903/23225/2926/8021/5438/10762/5431/7175/6396/129401/23511/5435/9631/5433/53371/3843/5439/5430/5901/5432/55746/5436/3836/8480/23279/4927/9688/6233/79902 47 Vesicular_stomatitis_Indiana_virus R-HSA-190236 Signaling by FGFR 36/771 87/10654 4.223009580496139e-19 2.647048463305401e-18 1.3608992943909933e-18 2962/7311/3178/2963/5437/5518/5441/5434/5440/4670/6464/5438/5431/3845/2549/5435/4686/7316/5433/200734/5439/3185/5430/5432/22916/5436/5725/6714/6654/7314/6233/2885/161742/3187/5515/5516 36 Vesicular_stomatitis_Indiana_virus R-HSA-2980766 Nuclear Envelope Breakdown 28/771 52/10654 5.86570550877367e-19 3.6562897671355876e-18 1.8797699525192816e-18 4000/23165/9972/348995/4928/79023/81929/57122/23636/5903/5347/23225/8021/10762/7175/6396/129401/23511/9631/53371/55746/983/7112/8480/23279/4927/9688/79902 28 Vesicular_stomatitis_Indiana_virus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 32/771 69/10654 6.221211856848765e-19 3.856463924521721e-18 1.982683394913128e-18 23165/6119/6118/9972/348995/2932/4928/79023/472/81929/57122/23636/5903/23225/8021/3309/6117/10762/7175/6396/129401/23511/9631/3312/53371/9531/55746/8480/23279/4927/9688/79902 32 Vesicular_stomatitis_Indiana_virus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 28/771 54/10654 2.2457648324952007e-18 1.3844770011316568e-17 7.117866559903818e-18 10450/404672/7311/56949/5437/5441/5434/5440/5438/9716/5431/2033/8450/5435/7316/9978/5433/27339/7874/5439/10987/5430/5432/5436/7314/6233/8451/10980 28 Vesicular_stomatitis_Indiana_virus R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 15/771 15/10654 6.8847462013110144e-18 4.108875126527105e-17 2.1124529217908378e-17 5519/2932/5518/324/5528/1499/5525/8312/5529/139285/5526/1452/5527/5515/5516 15 Vesicular_stomatitis_Indiana_virus R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 15/771 15/10654 6.8847462013110144e-18 4.108875126527105e-17 2.1124529217908378e-17 5519/2932/5518/324/5528/1499/5525/8312/5529/139285/5526/1452/5527/5515/5516 15 Vesicular_stomatitis_Indiana_virus R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 15/771 15/10654 6.8847462013110144e-18 4.108875126527105e-17 2.1124529217908378e-17 5519/2932/5518/324/5528/1499/5525/8312/5529/139285/5526/1452/5527/5515/5516 15 Vesicular_stomatitis_Indiana_virus R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 15/771 15/10654 6.8847462013110144e-18 4.108875126527105e-17 2.1124529217908378e-17 5519/2932/5518/324/5528/1499/5525/8312/5529/139285/5526/1452/5527/5515/5516 15 Vesicular_stomatitis_Indiana_virus R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 15/771 15/10654 6.8847462013110144e-18 4.108875126527105e-17 2.1124529217908378e-17 5519/2932/5518/324/5528/1499/5525/8312/5529/139285/5526/1452/5527/5515/5516 15 Vesicular_stomatitis_Indiana_virus R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 15/771 15/10654 6.8847462013110144e-18 4.108875126527105e-17 2.1124529217908378e-17 5519/2932/5518/324/5528/1499/5525/8312/5529/139285/5526/1452/5527/5515/5516 15 Vesicular_stomatitis_Indiana_virus R-HSA-3371556 Cellular response to heat stress 35/771 89/10654 9.346299501265188e-18 5.548438116624096e-17 2.852560360174505e-17 23165/6119/6118/9972/348995/2932/4928/1387/79023/472/81929/57122/23636/5903/23225/8021/3309/6117/10762/7175/6396/2033/129401/23511/9631/3312/1915/53371/9531/55746/8480/23279/4927/9688/79902 35 Vesicular_stomatitis_Indiana_virus R-HSA-168273 Influenza Viral RNA Transcription and Replication 43/771 134/10654 1.3089252493498556e-17 7.729548051423884e-17 3.973911560353025e-17 2962/23165/7311/9972/348995/4928/2963/79023/5437/6123/81929/57122/5441/5434/23636/5440/5903/23225/2926/8021/5438/10762/5431/7175/6396/129401/23511/5435/9631/5433/53371/3843/5439/5430/5432/55746/5436/8480/23279/4927/9688/6233/79902 43 Vesicular_stomatitis_Indiana_virus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 32/771 77/10654 3.4717157415382453e-17 2.0394057916261316e-016 1.0484983336252184e-16 672/23165/9972/348995/4928/79023/81929/57122/23636/5903/23225/8021/6117/10762/7175/6396/129401/23511/9631/57332/53371/55746/7329/6045/8480/8924/51588/23279/4927/9688/8554/79902 32 Vesicular_stomatitis_Indiana_virus R-HSA-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 16/771 18/10654 6.518646499172055e-17 3.8093340479536695e-16 1.9584530052337098e-16 8792/330/329/115650/4050/7187/10673/7186/51330/9020/8742/8600/4049/959/8740/4055 16 Vesicular_stomatitis_Indiana_virus R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 14/771 14/10654 9.676842745303716e-17 5.483544222338772e-16 2.819197142172481e-16 5519/2932/5518/324/5528/5525/8312/5529/139285/5526/1452/5527/5515/5516 14 Vesicular_stomatitis_Indiana_virus R-HSA-4839744 truncated APC mutants destabilize the destruction complex 14/771 14/10654 9.676842745303716e-17 5.483544222338772e-16 2.819197142172481e-16 5519/2932/5518/324/5528/5525/8312/5529/139285/5526/1452/5527/5515/5516 14 Vesicular_stomatitis_Indiana_virus R-HSA-4839748 AMER1 mutants destabilize the destruction complex 14/771 14/10654 9.676842745303716e-17 5.483544222338772e-16 2.819197142172481e-16 5519/2932/5518/324/5528/5525/8312/5529/139285/5526/1452/5527/5515/5516 14 Vesicular_stomatitis_Indiana_virus R-HSA-5467337 APC truncation mutants have impaired AXIN binding 14/771 14/10654 9.676842745303716e-17 5.483544222338772e-16 2.819197142172481e-16 5519/2932/5518/324/5528/5525/8312/5529/139285/5526/1452/5527/5515/5516 14 Vesicular_stomatitis_Indiana_virus R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 14/771 14/10654 9.676842745303716e-17 5.483544222338772e-16 2.819197142172481e-16 5519/2932/5518/324/5528/5525/8312/5529/139285/5526/1452/5527/5515/5516 14 Vesicular_stomatitis_Indiana_virus R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 14/771 14/10654 9.676842745303716e-17 5.483544222338772e-16 2.819197142172481e-16 5519/2932/5518/324/5528/5525/8312/5529/139285/5526/1452/5527/5515/5516 14 Vesicular_stomatitis_Indiana_virus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 29/771 65/10654 1.042516164225124e-16 5.877905207339644e-16 3.0219458238316216e-16 10450/404672/7311/6119/6118/56949/5437/5441/5434/5440/5438/9716/6117/5431/2033/8450/5435/7316/9978/5433/27339/7874/5439/5430/5432/5436/7314/6233/8451 29 Vesicular_stomatitis_Indiana_virus R-HSA-913531 Interferon Signaling 52/771 199/10654 1.0499607256298434e-16 5.890279670783422e-16 3.0283077770797597e-16 3459/23165/7311/9972/348995/5777/4928/3837/79023/3838/81929/57122/5610/23636/8638/5903/3717/23225/7706/5300/8021/9775/10762/7175/6396/129401/23511/5770/9631/7316/5771/53371/6773/3458/7297/55746/7324/5696/4734/3836/8480/6772/9830/23279/4927/9688/7314/6233/3841/8554/79902/3716 52 Vesicular_stomatitis_Indiana_virus R-HSA-5578749 Transcriptional regulation by small RNAs 37/771 106/10654 1.1098070028180074e-16 6.195042075431862e-16 3.184992079310124e-16 23165/9972/348995/4928/79023/5437/81929/57122/5441/5434/23636/5440/5903/23225/8021/5438/10762/5431/7175/6396/129401/23511/5435/9631/5433/53371/5439/5430/5901/5432/55746/5436/8480/23279/4927/9688/79902 37 Vesicular_stomatitis_Indiana_virus R-HSA-6782135 Dual incision in TC-NER 29/771 66/10654 1.7340706851489953e-16 9.631818360085013e-16 4.951905864834026e-16 10450/404672/7311/6119/6118/56949/5437/5441/5434/5440/5438/9716/6117/5431/2033/8450/5435/7316/9978/5433/27339/7874/5439/5430/5432/5436/7314/6233/8451 29 Vesicular_stomatitis_Indiana_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 49/771 182/10654 2.2302194529527416e-16 1.2326631656221557e-15 6.337361992315803e-16 672/7158/23165/5905/9972/348995/4928/1387/79023/81929/57122/23636/5903/23225/8021/3183/6117/10762/6294/7175/6396/2033/129401/23511/9631/57332/53371/1655/7428/3065/7157/5970/4792/3190/55746/7329/6045/6790/4791/8480/8924/9212/51588/23279/4927/9688/8554/4869/79902 49 Vesicular_stomatitis_Indiana_virus R-HSA-8851708 Signaling by FGFR2 IIIa TM 16/771 19/10654 3.852794458063922e-16 2.119036951935157e-15 1.0894382678116767e-15 2962/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 16 Vesicular_stomatitis_Indiana_virus R-HSA-71387 Metabolism of carbohydrates 64/771 295/10654 6.337213069573564e-16 3.468464909298312e-15 1.7832055261239095e-15 5105/8707/5519/23165/7311/2526/5106/11041/79369/9972/348995/4928/79023/5518/81929/57122/23636/5903/10402/10675/10678/23225/6548/8021/6483/5836/10762/2528/2523/7175/8708/6396/170384/129401/23511/5528/55454/9631/7316/28/375790/8703/53371/8704/10317/2527/55746/6484/8702/2524/2683/8480/6482/23279/4927/9688/7314/6233/10690/5515/10331/79902/2525/5516 64 Vesicular_stomatitis_Indiana_virus R-HSA-6809371 Formation of the cornified envelope 40/771 129/10654 6.91793136045735e-16 3.767921838074343e-15 1.9371621796273008e-15 353142/3713/7051/1828/1475/353133/6703/6704/6699/353132/1041/353135/6705/7062/6700/353139/26239/353143/6701/353131/149018/353141/1823/5493/353137/6707/353145/6698/2125/84648/353134/126638/448835/23581/6706/254910/5266/199834/353140/353144 40 Vesicular_stomatitis_Indiana_virus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 31/771 79/10654 7.673624829808029e-16 4.159327081664062e-15 2.138391256920824e-15 10450/404672/7311/6119/6118/56949/5437/5441/5434/5440/5438/9716/6117/5431/2033/8450/5435/7316/9978/5433/27339/7874/5439/10987/5430/5432/5436/7314/6233/8451/10980 31 Vesicular_stomatitis_Indiana_virus R-HSA-196299 Beta-catenin phosphorylation cascade 15/771 17/10654 8.157395831453359e-16 4.400287559082052e-15 2.2622737427309924e-15 5519/2932/5518/324/5528/1499/5525/8312/5529/139285/5526/1452/5527/5515/5516 15 Vesicular_stomatitis_Indiana_virus R-HSA-2990846 SUMOylation 49/771 188/10654 9.254188869176114e-16 4.968038235031387e-15 2.554165449664322e-15 672/7158/23165/5905/9972/348995/4928/1387/79023/81929/57122/23636/5903/23225/8021/3183/6117/10762/6294/7175/6396/2033/129401/23511/9631/57332/53371/1655/7428/3065/7157/5970/4792/3190/55746/7329/6045/6790/4791/8480/8924/9212/51588/23279/4927/9688/8554/4869/79902 49 Vesicular_stomatitis_Indiana_virus R-HSA-4551638 SUMOylation of chromatin organization proteins 29/771 71/10654 1.8712261518297752e-15 9.950311575132738e-15 5.115649444762869e-15 23165/9972/348995/4928/79023/81929/57122/23636/5903/23225/8021/10762/7175/6396/129401/23511/9631/57332/53371/3065/55746/7329/6045/8480/23279/4927/9688/8554/79902 29 Vesicular_stomatitis_Indiana_virus R-HSA-70171 Glycolysis 29/771 71/10654 1.8712261518297752e-15 9.950311575132738e-15 5.115649444762869e-15 5519/23165/9972/348995/4928/79023/5518/81929/57122/23636/5903/23225/8021/10762/7175/6396/129401/23511/5528/9631/53371/55746/8480/23279/4927/9688/5515/79902/5516 29 Vesicular_stomatitis_Indiana_virus R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 19/771 31/10654 1.0679649491816884e-14 5.652154117838936e-14 2.9058827812888044e-14 1857/5519/2932/5518/324/5528/1499/5525/8312/5529/139285/1856/89780/5526/1452/5527/1855/5515/5516 19 Vesicular_stomatitis_Indiana_virus R-HSA-5696398 Nucleotide Excision Repair 35/771 111/10654 2.6260893190978637e-14 1.383320289214931e-13 7.111919678110351e-14 10450/404672/7311/6119/6118/56949/5437/5441/5434/5440/5438/5887/9716/6117/5431/2033/8450/5435/7316/9978/5433/27339/7874/5439/10987/5430/5432/5436/7329/5886/7314/6233/8451/8554/10980 35 Vesicular_stomatitis_Indiana_virus R-HSA-211000 Gene Silencing by RNA 39/771 136/10654 2.886903720278988e-14 1.5136009225014136e-13 7.781717849055022e-14 23165/9972/348995/4928/79023/5437/81929/57122/5441/5434/23636/5440/5903/23225/8021/57510/5438/10762/5431/7175/6396/129401/23511/5435/9631/54487/5433/53371/5439/5430/5901/5432/55746/5436/8480/23279/4927/9688/79902 39 Vesicular_stomatitis_Indiana_virus R-HSA-141424 Amplification of signal from the kinetochores 32/771 96/10654 5.922690418430677e-14 3.0765086340181574e-13 1.581693152680317e-13 701/7514/5519/9184/5905/348995/4928/79023/5518/81929/57122/5903/5347/6396/5528/25936/5525/80776/5501/5529/25909/991/5526/4085/55746/80152/9212/23279/5527/5515/79902/5516 32 Vesicular_stomatitis_Indiana_virus R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 32/771 96/10654 5.922690418430677e-14 3.0765086340181574e-13 1.581693152680317e-13 701/7514/5519/9184/5905/348995/4928/79023/5518/81929/57122/5903/5347/6396/5528/25936/5525/80776/5501/5529/25909/991/5526/4085/55746/80152/9212/23279/5527/5515/79902/5516 32 Vesicular_stomatitis_Indiana_virus R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 16/771 23/10654 7.394216372501945e-14 3.8231846866116043e-13 1.9655738889794158e-13 2962/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 16 Vesicular_stomatitis_Indiana_virus R-HSA-70326 Glucose metabolism 31/771 91/10654 7.477049143580521e-14 3.8482794216042863e-13 1.97847558217389e-13 5105/5519/23165/5106/9972/348995/4928/79023/5518/81929/57122/23636/5903/23225/8021/10762/7175/6396/129401/23511/5528/9631/53371/55746/8480/23279/4927/9688/5515/79902/5516 31 Vesicular_stomatitis_Indiana_virus R-HSA-72086 mRNA Capping 17/771 29/10654 7.850417425778489e-13 4.021994681152267e-12 2.0677859886212988e-12 2962/404672/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 17 Vesicular_stomatitis_Indiana_virus R-HSA-72306 tRNA processing 32/771 107/10654 1.7363184078871909e-12 8.855223880224674e-12 4.552643480967372e-12 10898/29894/23165/55006/9972/348995/4928/79023/81929/57122/23636/5903/23225/8021/10762/7175/6396/129401/23511/9631/53371/5901/55746/10978/1478/8480/10556/23279/4927/9688/55644/79902 32 Vesicular_stomatitis_Indiana_virus R-HSA-4791275 Signaling by WNT in cancer 18/771 34/10654 1.7880033271906963e-12 9.077555353429688e-12 4.66694843201001e-12 5519/2932/5518/324/5528/1499/5525/8312/5529/80351/139285/89780/5526/8658/1452/5527/5515/5516 18 Vesicular_stomatitis_Indiana_virus R-HSA-5663220 RHO GTPases Activate Formins 37/771 140/10654 2.092557852364216e-12 1.0575900497084012e-11 5.4372769231654365e-12 701/1857/7514/5519/9184/5905/348995/4928/79023/5518/81929/57122/5903/5347/6396/5528/3688/25936/5525/80776/5501/5529/25909/991/1856/5526/4085/55746/80152/9212/6714/23279/5527/1855/5515/79902/5516 37 Vesicular_stomatitis_Indiana_virus R-HSA-5655253 Signaling by FGFR2 in disease 20/771 43/10654 2.3895798141212396e-12 1.2022908302439599e-11 6.18121188642171e-12 2962/2963/5437/5441/5434/5440/5438/5431/3845/2549/5435/4686/5433/5439/5430/5432/22916/5436/6654/2885 20 Vesicular_stomatitis_Indiana_virus R-HSA-1226099 Signaling by FGFR in disease 24/771 63/10654 3.1327633746946326e-12 1.5691787975032937e-11 8.067454555134675e-12 2962/2963/5437/5441/5434/5440/5438/5431/3845/6776/2549/5435/6777/4686/5433/5439/6774/5430/5432/22916/5436/6772/6654/2885 24 Vesicular_stomatitis_Indiana_virus R-HSA-203927 MicroRNA (miRNA) biogenesis 15/771 24/10654 4.8426733764683546e-12 2.414879790398886e-11 1.241536846926156e-11 5437/5441/5434/5440/57510/5438/5431/5435/54487/5433/5439/5430/5901/5432/5436 15 Vesicular_stomatitis_Indiana_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 29/771 94/10654 8.16710051931383e-12 4.0546401693230605e-11 2.084569671441071e-11 8454/6500/5519/330/7311/23098/11035/8945/329/5518/7187/351/23291/4790/5599/5528/5606/7316/79155/7321/5608/5970/4792/4793/4791/7314/6233/5515/5516 29 Vesicular_stomatitis_Indiana_virus R-HSA-2500257 Resolution of Sister Chromatid Cohesion 34/771 126/10654 8.811347255857386e-12 4.3552121678731216e-11 2.239099604085253e-11 701/7514/5519/9184/5905/348995/4928/79023/5518/81929/57122/5903/5347/6396/5528/25936/5525/80776/5501/5529/25909/55869/991/5526/4085/55746/983/80152/9212/23279/5527/5515/79902/5516 34 Vesicular_stomatitis_Indiana_virus R-HSA-113418 Formation of the Early Elongation Complex 17/771 33/10654 1.3385204591573436e-11 6.55816574312026e-11 3.3716810462800484e-11 2962/404672/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 17 Vesicular_stomatitis_Indiana_virus R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 17/771 33/10654 1.3385204591573436e-11 6.55816574312026e-11 3.3716810462800484e-11 2962/404672/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 17 Vesicular_stomatitis_Indiana_virus R-HSA-9033658 Blood group systems biosynthesis 14/771 22/10654 1.7866868734539005e-11 8.715924660935983e-11 4.481027032735641e-11 8707/2526/10402/2528/2523/8708/170384/28/10317/2527/6484/2524/10690/2525 14 Vesicular_stomatitis_Indiana_virus R-HSA-166166 MyD88-independent TLR4 cascade 29/771 99/10654 3.403239876386607e-11 1.6458772160800744e-10 8.461776099182671e-11 8454/6500/5519/330/7311/23098/11035/8945/329/5518/7187/351/23291/4790/5599/5528/5606/7316/79155/7321/5608/5970/4792/4793/4791/7314/6233/5515/5516 29 Vesicular_stomatitis_Indiana_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 29/771 99/10654 3.403239876386607e-11 1.6458772160800744e-10 8.461776099182671e-11 8454/6500/5519/330/7311/23098/11035/8945/329/5518/7187/351/23291/4790/5599/5528/5606/7316/79155/7321/5608/5970/4792/4793/4791/7314/6233/5515/5516 29 Vesicular_stomatitis_Indiana_virus R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 15/771 27/10654 5.2378657321289116e-11 2.5114894664310424e-10 1.2912057675243563e-10 2962/404672/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 15 Vesicular_stomatitis_Indiana_virus R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 15/771 27/10654 5.2378657321289116e-11 2.5114894664310424e-10 1.2912057675243563e-10 2962/404672/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 15 Vesicular_stomatitis_Indiana_virus R-HSA-1839126 FGFR2 mutant receptor activation 16/771 33/10654 1.7652940939820764e-10 8.428340312544212e-10 4.3331743046010214e-10 2962/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 16 Vesicular_stomatitis_Indiana_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 22/771 63/10654 1.8592607504601343e-10 8.839366788204537e-10 4.544491040375351e-10 7311/11035/1387/5437/5441/5434/5440/6778/4790/2033/5435/7316/1499/1660/5970/4792/4793/4791/3428/7314/9533/6233 22 Vesicular_stomatitis_Indiana_virus R-HSA-9037629 Lewis blood group biosynthesis 12/771 18/10654 2.3506976978030394e-10 1.112861948073844e-9 5.7214405436201e-10 8707/2526/10402/2528/8708/170384/10317/2527/6484/2524/10690/2525 12 Vesicular_stomatitis_Indiana_virus R-HSA-68875 Mitotic Prophase 34/771 142/10654 3.0712536975613734e-10 1.4478767431360761e-9 7.44381701133849e-10 4000/5519/23165/4926/9972/348995/4928/79023/5518/81929/57122/23636/5903/5347/23225/8021/10762/7175/6396/129401/23511/9631/53371/55746/983/7112/2801/8480/23279/4927/9688/5515/79902/5516 34 Vesicular_stomatitis_Indiana_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 73/771 473/10654 3.290340247365282e-10 1.5446701914409398e-9 7.941451026453092e-10 7409/2962/3082/5519/7311/3178/5777/51741/2963/3643/5437/5159/5518/5155/51606/5441/5434/5440/4670/3717/3791/8065/6464/1956/1289/4914/6778/5438/5431/3845/6776/5528/2549/5435/3688/6777/5770/4686/7316/1499/5433/1950/5771/200734/5439/3630/3185/6774/5430/11059/5062/83737/5432/4233/3480/22916/4734/5436/5725/11140/10768/10413/7422/6772/6714/6654/7314/6233/2885/161742/3187/5515/5516 73 Vesicular_stomatitis_Indiana_virus R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 29/771 110/10654 5.549622010928334e-10 2.594448290108996e-9 1.3338565184161086e-9 1017/51343/7311/25906/11065/8881/4790/29882/119504/7316/246184/890/7321/6774/5970/8900/51529/1026/7324/64682/29945/10393/8697/7314/996/6233/51434/1027/51433 29 Vesicular_stomatitis_Indiana_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 12/771 19/10654 5.961270504421413e-10 2.763861779322655e-9 1.4209553007494275e-9 7311/6464/1956/3845/2549/7316/1950/11140/6654/7314/6233/2885 12 Vesicular_stomatitis_Indiana_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 12/771 19/10654 5.961270504421413e-10 2.763861779322655e-9 1.4209553007494275e-9 7311/6464/1956/3845/2549/7316/1950/11140/6654/7314/6233/2885 12 Vesicular_stomatitis_Indiana_virus R-HSA-112382 Formation of RNA Pol II elongation complex 21/771 61/10654 6.546558576630856e-10 3.0103437389261557e-9 1.547676488349314e-9 2962/404672/1025/79577/54623/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436/123169 21 Vesicular_stomatitis_Indiana_virus R-HSA-75955 RNA Polymerase II Transcription Elongation 21/771 61/10654 6.546558576630856e-10 3.0103437389261557e-9 1.547676488349314e-9 2962/404672/1025/79577/54623/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436/123169 21 Vesicular_stomatitis_Indiana_virus R-HSA-6804757 Regulation of TP53 Degradation 16/771 36/10654 8.991567895067657e-10 4.1177710931697595e-9 2.1170265119214074e-9 5519/1017/7311/5518/472/7316/7874/890/7157/8900/983/7314/6233/5527/5515/5516 16 Vesicular_stomatitis_Indiana_virus R-HSA-167169 HIV Transcription Elongation 18/771 46/10654 9.964393215483198e-10 4.508084349908124e-9 2.3176941774553452e-9 2962/404672/1025/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 18 Vesicular_stomatitis_Indiana_virus R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 18/771 46/10654 9.964393215483198e-10 4.508084349908124e-9 2.3176941774553452e-9 2962/404672/1025/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 18 Vesicular_stomatitis_Indiana_virus R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 18/771 46/10654 9.964393215483198e-10 4.508084349908124e-9 2.3176941774553452e-9 2962/404672/1025/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 18 Vesicular_stomatitis_Indiana_virus R-HSA-3700989 Transcriptional Regulation by TP53 60/771 365/10654 1.1598722588230287e-9 5.226412346985696e-9 2.6870006249630934e-9 672/2962/404672/898/5519/1025/1017/2810/7311/6119/6118/7161/1387/2963/5437/5518/472/5441/9134/5434/5440/5300/5438/580/6117/5431/2033/7159/5435/10128/7316/84126/5728/3276/5433/7874/890/5439/3065/5608/5430/7157/8900/1457/5432/983/1026/26013/5436/6790/9212/8148/7314/6233/5527/5515/1027/4869/29117/5516 60 Vesicular_stomatitis_Indiana_virus R-HSA-2559583 Cellular Senescence 40/771 195/10654 1.23378801724827e-9 5.537240621410236e-9 2.846803509271798e-9 898/1017/51343/7311/472/25906/9134/11065/8726/8881/4790/29882/5599/119504/5606/57332/7316/246184/890/7321/2146/5608/6774/7157/5970/8900/51529/1026/7324/6045/64682/29945/10393/8697/7314/996/6233/51434/1027/51433 40 Vesicular_stomatitis_Indiana_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 16/771 37/10654 1.4787852874939702e-9 6.610346982343563e-9 3.398508440120343e-9 5519/1017/7311/5518/472/7316/7874/890/7157/8900/983/7314/6233/5527/5515/5516 16 Vesicular_stomatitis_Indiana_virus R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 18/771 48/10654 2.2500976741620073e-9 1.0018292025435605e-8 5.150599521473602e-9 2962/404672/1025/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/5430/5432/22916/5436 18 Vesicular_stomatitis_Indiana_virus R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 15/771 34/10654 3.456779517197788e-9 1.526971109565322e-8 7.850456591066672e-9 2962/1025/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 15 Vesicular_stomatitis_Indiana_virus R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 15/771 34/10654 3.456779517197788e-9 1.526971109565322e-8 7.850456591066672e-9 2962/1025/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 15 Vesicular_stomatitis_Indiana_virus R-HSA-69231 Cyclin D associated events in G1 17/771 44/10654 3.6832611494332277e-9 1.6143043006500318e-8 8.299453576847899e-9 8454/6500/5519/7311/5518/3717/6502/7316/595/1163/1026/6714/7314/6233/5515/1027/5516 17 Vesicular_stomatitis_Indiana_virus R-HSA-69236 G1 Phase 17/771 44/10654 3.6832611494332277e-9 1.6143043006500318e-8 8.299453576847899e-9 8454/6500/5519/7311/5518/3717/6502/7316/595/1163/1026/6714/7314/6233/5515/1027/5516 17 Vesicular_stomatitis_Indiana_virus R-HSA-6807505 RNA polymerase II transcribes snRNA genes 22/771 74/10654 5.987384290958391e-9 2.6139475386985656e-8 1.3438814628077815e-8 2962/6617/1025/79664/2963/5437/5441/5434/5440/51593/5438/5431/5435/4686/5433/5439/2959/5430/5432/22916/5436/51585 22 Vesicular_stomatitis_Indiana_virus R-HSA-5633007 Regulation of TP53 Activity 34/771 160/10654 8.522226546364887e-9 3.706177591093567e-8 1.905418256796393e-8 672/5519/1017/7311/6119/6118/7161/5518/472/5300/580/6117/2033/7159/7316/84126/7874/890/3065/5608/7157/8900/1457/983/26013/6790/9212/8148/7314/6233/5527/5515/29117/5516 34 Vesicular_stomatitis_Indiana_virus R-HSA-68877 Mitotic Prometaphase 39/771 200/10654 8.989059425377408e-9 3.886171111964389e-8 1.9979564399629285e-8 701/7514/5519/9184/4926/5905/348995/4928/79023/5518/81929/57122/5903/5347/6396/5528/25936/5525/80776/5501/5529/25909/55869/991/5526/4085/5108/1457/55746/983/80152/4751/9212/23279/5577/5527/5515/79902/5516 39 Vesicular_stomatitis_Indiana_virus R-HSA-167287 HIV elongation arrest and recovery 15/771 36/10654 9.040023709649783e-9 3.886171111964389e-8 1.9979564399629285e-8 2962/1025/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 15 Vesicular_stomatitis_Indiana_virus R-HSA-167290 Pausing and recovery of HIV elongation 15/771 36/10654 9.040023709649783e-9 3.886171111964389e-8 1.9979564399629285e-8 2962/1025/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 15 Vesicular_stomatitis_Indiana_virus R-HSA-167161 HIV Transcription Initiation 17/771 47/10654 1.1960612295158983e-8 5.026144942010629e-8 2.5840392421632657e-8 2962/404672/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/2959/5430/5432/5436/8148 17 Vesicular_stomatitis_Indiana_virus R-HSA-167162 RNA Polymerase II HIV Promoter Escape 17/771 47/10654 1.1960612295158983e-8 5.026144942010629e-8 2.5840392421632657e-8 2962/404672/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/2959/5430/5432/5436/8148 17 Vesicular_stomatitis_Indiana_virus R-HSA-73776 RNA Polymerase II Promoter Escape 17/771 47/10654 1.1960612295158983e-8 5.026144942010629e-8 2.5840392421632657e-8 2962/404672/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/2959/5430/5432/5436/8148 17 Vesicular_stomatitis_Indiana_virus R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 17/771 47/10654 1.1960612295158983e-8 5.026144942010629e-8 2.5840392421632657e-8 2962/404672/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/2959/5430/5432/5436/8148 17 Vesicular_stomatitis_Indiana_virus R-HSA-75953 RNA Polymerase II Transcription Initiation 17/771 47/10654 1.1960612295158983e-8 5.026144942010629e-8 2.5840392421632657e-8 2962/404672/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/2959/5430/5432/5436/8148 17 Vesicular_stomatitis_Indiana_virus R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 17/771 47/10654 1.1960612295158983e-8 5.026144942010629e-8 2.5840392421632657e-8 2962/404672/2963/5437/5441/5434/5440/5438/5431/5435/5433/5439/2959/5430/5432/5436/8148 17 Vesicular_stomatitis_Indiana_virus R-HSA-674695 RNA Polymerase II Pre-transcription Events 23/771 84/10654 1.5553212618338166e-8 6.511456924543068e-8 3.347667130734217e-8 2962/404672/1025/79577/54623/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/2959/5430/5432/22916/5436/8148/123169 23 Vesicular_stomatitis_Indiana_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 23/771 85/10654 1.9890531803750105e-8 8.235120547530487e-8 4.233836251099265e-8 8454/6500/5519/7311/8945/5518/351/23291/4790/5599/5528/5606/7316/79155/5608/5970/4792/4793/4791/7314/6233/5515/5516 23 Vesicular_stomatitis_Indiana_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 23/771 85/10654 1.9890531803750105e-8 8.235120547530487e-8 4.233836251099265e-8 8454/6500/5519/7311/8945/5518/351/23291/4790/5599/5528/5606/7316/79155/5608/5970/4792/4793/4791/7314/6233/5515/5516 23 Vesicular_stomatitis_Indiana_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 23/771 85/10654 1.9890531803750105e-8 8.235120547530487e-8 4.233836251099265e-8 8454/6500/5519/7311/8945/5518/351/23291/4790/5599/5528/5606/7316/79155/5608/5970/4792/4793/4791/7314/6233/5515/5516 23 Vesicular_stomatitis_Indiana_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 10/771 16/10654 1.9972428353040675e-8 8.238626695629278e-8 4.235638830288812e-8 8454/6500/7311/8945/23291/4790/7316/79155/7314/6233 10 Vesicular_stomatitis_Indiana_virus R-HSA-6805567 Keratinization 40/771 214/10654 2.0271921700997677e-8 8.331537050739704e-8 4.283405857777801e-8 353142/3713/7051/1828/1475/353133/6703/6704/6699/353132/1041/353135/6705/7062/6700/353139/26239/353143/6701/353131/149018/353141/1823/5493/353137/6707/353145/6698/2125/84648/353134/126638/448835/23581/6706/254910/5266/199834/353140/353144 40 Vesicular_stomatitis_Indiana_virus R-HSA-5619102 SLC transporter disorders 25/771 99/10654 2.2235918985832205e-8 9.10536536573129e-8 4.681246102280464e-8 23165/9972/348995/4928/79023/81929/57122/23636/5903/23225/8021/10762/7175/6396/129401/23511/9631/53371/55746/55630/8480/23279/4927/9688/79902 25 Vesicular_stomatitis_Indiana_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 29/771 129/10654 2.8650863742936356e-8 1.1689552407118033e-7 6.009827112393924e-8 8454/6500/5519/330/7311/23098/11035/8945/329/5518/7187/351/23291/4790/5599/5528/5606/7316/79155/7321/5608/5970/4792/4793/4791/7314/6233/5515/5516 29 Vesicular_stomatitis_Indiana_virus R-HSA-1643713 Signaling by EGFR in Cancer 12/771 25/10654 4.0944185789523713e-8 1.6644701614436812e-7 8.557366061273454e-8 7311/6464/1956/3845/2549/7316/1950/11140/6654/7314/6233/2885 12 Vesicular_stomatitis_Indiana_virus R-HSA-432142 Platelet sensitization by LDL 10/771 17/10654 4.5361487329561744e-8 1.8373858766703348e-7 9.446359512293307e-8 5519/5777/5518/5528/5525/5529/5526/5527/5515/5516 10 Vesicular_stomatitis_Indiana_virus R-HSA-5675221 Negative regulation of MAPK pathway 15/771 40/10654 4.9638761486828486e-8 2.003406129072718e-7 1.0299902042704283e-7 5519/7311/5518/3845/5528/7316/5525/5529/5526/7314/6233/11221/5527/5515/5516 15 Vesicular_stomatitis_Indiana_virus R-HSA-877312 Regulation of IFNG signaling 9/771 14/10654 7.482257607760598e-8 3.0089939196800684e-7 1.546982519921829e-7 3459/5777/3717/5770/5771/3458/6772/8554/3716 9 Vesicular_stomatitis_Indiana_virus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 19/771 65/10654 8.835481622945958e-8 3.540503707480487e-7 1.8202420787121748e-7 672/2962/404672/1025/2963/5437/472/5441/5434/5440/5438/5431/5435/5433/5439/5430/7157/5432/5436 19 Vesicular_stomatitis_Indiana_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 23/771 92/10654 9.928281624751793e-8 3.964246257285235e-7 2.0380963964652493e-7 8454/6500/5519/7311/8945/5518/351/23291/4790/5599/5528/5606/7316/79155/5608/5970/4792/4793/4791/7314/6233/5515/5516 23 Vesicular_stomatitis_Indiana_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 23/771 93/10654 1.2305015689204522e-7 4.8785256548719e-7 2.508145284613755e-7 8454/6500/5519/7311/8945/5518/351/23291/4790/5599/5528/5606/7316/79155/5608/5970/4792/4793/4791/7314/6233/5515/5516 23 Vesicular_stomatitis_Indiana_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 23/771 93/10654 1.2305015689204522e-7 4.8785256548719e-7 2.508145284613755e-7 8454/6500/5519/7311/8945/5518/351/23291/4790/5599/5528/5606/7316/79155/5608/5970/4792/4793/4791/7314/6233/5515/5516 23 Vesicular_stomatitis_Indiana_virus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 13/771 32/10654 1.2903133285509223e-7 5.079759840821525e-7 2.611603708387462e-7 7514/7311/4088/7040/64750/7316/5501/51377/9958/9040/4738/7314/6233 13 Vesicular_stomatitis_Indiana_virus R-HSA-5673000 RAF activation 13/771 32/10654 1.2903133285509223e-7 5.079759840821525e-7 2.611603708387462e-7 5519/5518/3717/3845/5528/5525/5529/5526/5245/6714/5527/5515/5516 13 Vesicular_stomatitis_Indiana_virus R-HSA-167172 Transcription of the HIV genome 20/771 73/10654 1.3344596208537566e-7 5.235187743349353e-7 2.6915122275592887e-7 2962/404672/1025/2963/5437/5441/5434/5440/5438/5431/5435/4686/5433/5439/2959/5430/5432/22916/5436/8148 20 Vesicular_stomatitis_Indiana_virus R-HSA-5696395 Formation of Incision Complex in GG-NER 15/771 43/10654 1.5224434305980952e-7 5.951852017878268e-7 3.0599633228232397e-7 404672/7311/6119/6118/5887/6117/8450/7316/9978/7329/5886/7314/6233/8451/8554 15 Vesicular_stomatitis_Indiana_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 23/771 95/10654 1.8706767099185545e-7 7.262627226742623e-7 3.733858448498882e-7 8454/6500/5519/7311/8945/5518/351/23291/4790/5599/5528/5606/7316/79155/5608/5970/4792/4793/4791/7314/6233/5515/5516 23 Vesicular_stomatitis_Indiana_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 23/771 95/10654 1.8706767099185545e-7 7.262627226742623e-7 3.733858448498882e-7 8454/6500/5519/7311/8945/5518/351/23291/4790/5599/5528/5606/7316/79155/5608/5970/4792/4793/4791/7314/6233/5515/5516 23 Vesicular_stomatitis_Indiana_virus R-HSA-2022854 Keratan sulfate biosynthesis 12/771 28/10654 1.9546987633185945e-7 7.562662111874011e-7 3.888112240648239e-7 11041/79369/10402/10678/6483/8703/8704/6484/8702/2683/6482/10331 12 Vesicular_stomatitis_Indiana_virus R-HSA-73894 DNA Repair 51/771 334/10654 2.4290751440173495e-7 9.365712410953492e-7 4.815095601090641e-7 10450/672/404672/1017/7158/7311/6119/6118/56949/5437/3838/472/5441/5434/5440/7706/5438/5887/580/9716/6117/5431/4350/5599/2033/8450/5435/7316/84126/9978/5433/328/27339/7874/890/5439/10987/5430/7157/8900/5432/5436/7329/5886/8924/51588/7314/6233/8451/8554/10980 51 Vesicular_stomatitis_Indiana_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 23/771 97/10654 2.8064424978508886e-7 1.0783659186947592e-6 5.544089721781856e-7 8454/6500/5519/7311/8945/5518/351/23291/4790/5599/5528/5606/7316/79155/5608/5970/4792/4793/4791/7314/6233/5515/5516 23 Vesicular_stomatitis_Indiana_virus R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 12/771 29/10654 3.1162342569629207e-7 1.193315643792627e-6 6.135068700613187e-7 5437/5441/5434/5440/5438/5431/5435/5433/5439/5430/5432/5436 12 Vesicular_stomatitis_Indiana_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 23/771 98/10654 3.4210582732969126e-7 1.3011618246234359e-6 6.689526971513678e-7 8454/6500/5519/7311/8945/5518/351/23291/4790/5599/5528/5606/7316/79155/5608/5970/4792/4793/4791/7314/6233/5515/5516 23 Vesicular_stomatitis_Indiana_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 23/771 98/10654 3.4210582732969126e-7 1.3011618246234359e-6 6.689526971513678e-7 8454/6500/5519/7311/8945/5518/351/23291/4790/5599/5528/5606/7316/79155/5608/5970/4792/4793/4791/7314/6233/5515/5516 23 Vesicular_stomatitis_Indiana_virus R-HSA-450294 MAP kinase activation 18/771 64/10654 3.6727047566062234e-7 1.3921536273351968e-6 7.15733359395523e-7 8454/6500/5519/7311/8945/5518/23291/4790/5599/5528/5606/7316/79155/5608/7314/6233/5515/5516 18 Vesicular_stomatitis_Indiana_virus R-HSA-1295596 Spry regulation of FGF signaling 9/771 16/10654 3.7441968477329333e-7 1.4144743646991081e-6 7.272088862511599e-7 7311/5518/7316/6714/7314/6233/2885/5515/5516 9 Vesicular_stomatitis_Indiana_virus R-HSA-1236394 Signaling by ERBB4 17/771 58/10654 4.040413560357624e-7 1.5212563807789445e-6 7.82107605466612e-7 7311/51741/6464/1956/3845/6776/7316/1950/11059/83737/4734/10413/6714/6654/7314/6233/2885 17 Vesicular_stomatitis_Indiana_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 20/771 78/10654 4.349902390930647e-7 1.6323045092388582e-6 8.39199616345712e-7 7311/1387/7187/5094/351/7706/5300/7186/4790/2033/7316/1540/7321/5970/4792/83737/4793/4791/7314/6233 20 Vesicular_stomatitis_Indiana_virus R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 11/771 25/10654 4.620788008197998e-7 1.7281747150660513e-6 8.884883608745625e-7 7514/5519/1017/5518/5347/993/890/8900/983/5515/5516 11 Vesicular_stomatitis_Indiana_virus R-HSA-168898 Toll-like Receptor Cascades 30/771 155/10654 5.550371751835774e-7 2.068942559986624e-6 1.063683762897711e-6 8454/6500/5519/330/7311/23098/11035/8945/329/5518/6280/7187/351/23291/4790/5599/5528/5606/7316/79155/7321/5608/5970/4792/4793/4791/7314/6233/5515/5516 30 Vesicular_stomatitis_Indiana_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 15/771 47/10654 5.742430579768049e-7 2.133446063079388e-6 1.0968462731658737e-6 8454/6500/22938/7311/3091/1387/79885/2033/7316/9978/55869/3065/4609/7314/6233 15 Vesicular_stomatitis_Indiana_virus R-HSA-389513 CTLA4 inhibitory signaling 10/771 21/10654 6.295371484085225e-7 2.331157361433539e-6 1.1984935116479778e-6 5519/5518/5528/5525/5529/5526/6714/5527/5515/5516 10 Vesicular_stomatitis_Indiana_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 11/771 26/10654 7.488285902203195e-7 2.7637686783789424e-6 1.4209074357366175e-6 7514/7311/4088/7040/64750/7316/5501/51377/9958/7314/6233 11 Vesicular_stomatitis_Indiana_virus R-HSA-111367 SLBP independent Processing of Histone Pre-mRNAs 7/771 10/10654 1.0013060094118422e-6 3.671455367843421e-6 1.8875668839273808e-6 6637/6635/6634/4686/22916/6628/6636 7 Vesicular_stomatitis_Indiana_virus R-HSA-9020958 Interleukin-21 signaling 7/771 10/10654 1.0013060094118422e-6 3.671455367843421e-6 1.8875668839273808e-6 6776/6777/6774/6775/3718/6772/3716 7 Vesicular_stomatitis_Indiana_virus R-HSA-1538133 G0 and Early G1 11/771 27/10654 1.1814759601800537e-6 4.317967515706906e-6 2.219951401264082e-6 898/1017/9134/990/993/890/3065/8900/1859/983/4609 11 Vesicular_stomatitis_Indiana_virus R-HSA-71291 Metabolism of amino acids and derivatives 53/771 372/10654 1.298888269319887e-6 4.731664409665302e-6 2.4326410512211143e-6 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/6123/5687/4946/5705/5684/259307/10166/4947/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/10213/5709/5694/5699/5695/5710/5700/122706/5707/4953/5702/5693/5721/5696/5719/5691/5714/5690/51686/5704/6233/5717/9861 53 Vesicular_stomatitis_Indiana_virus R-HSA-5654736 Signaling by FGFR1 15/771 50/10654 1.4006464095426579e-6 5.085842302611205e-6 2.614730820743916e-6 7311/5518/6464/3845/2549/7316/200734/6714/6654/7314/6233/2885/161742/5515/5516 15 Vesicular_stomatitis_Indiana_virus R-HSA-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 8/771 14/10654 1.4723932272530943e-6 5.311978138192835e-6 2.7309916687584892e-6 898/1017/9134/890/7157/8900/1026/1027 8 Vesicular_stomatitis_Indiana_virus R-HSA-8983432 Interleukin-15 signaling 8/771 14/10654 1.4723932272530943e-6 5.311978138192835e-6 2.7309916687584892e-6 6464/6776/6777/6774/3718/6654/2885/3716 8 Vesicular_stomatitis_Indiana_virus R-HSA-195258 RHO GTPase Effectors 48/771 327/10654 1.7675837075437739e-6 6.356502948282418e-6 3.2680022663090017e-6 701/1857/7514/5519/1080/2810/9184/5905/348995/4928/79023/5518/3799/81929/57122/6280/5903/5347/999/5300/6396/5528/3688/1499/25936/5525/80776/5501/5529/25909/991/1856/5526/4085/5062/55746/80152/9212/6714/23279/54763/5527/1855/2885/5515/1027/79902/5516 48 Vesicular_stomatitis_Indiana_virus R-HSA-1638074 Keratan sulfate/keratin metabolism 12/771 34/10654 2.3482775205769686e-6 8.417787150438846e-6 4.327748717928969e-6 11041/79369/10402/10678/6483/8703/8704/6484/8702/2683/6482/10331 12 Vesicular_stomatitis_Indiana_virus R-HSA-448424 Interleukin-17 signaling 18/771 72/10654 2.434749038166114e-6 8.699963123638152e-6 4.47282089478723e-6 8454/6500/5519/7311/8945/5518/23291/4790/5599/5528/5606/7316/79155/5608/7314/6233/5515/5516 18 Vesicular_stomatitis_Indiana_virus R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 7/771 11/10654 2.5812152113088085e-6 9.164947680659757e-6 4.711878533635001e-6 3091/1387/2034/2033/64344/7422/768 7 Vesicular_stomatitis_Indiana_virus R-HSA-77588 SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs 7/771 11/10654 2.5812152113088085e-6 9.164947680659757e-6 4.711878533635001e-6 6637/6635/6634/4686/22916/6628/6636 7 Vesicular_stomatitis_Indiana_virus R-HSA-5654741 Signaling by FGFR3 13/771 40/10654 2.595634010631065e-6 9.187070536050647e-6 4.723252325504977e-6 7311/5518/6464/3845/2549/7316/6714/6654/7314/6233/2885/5515/5516 13 Vesicular_stomatitis_Indiana_virus R-HSA-186763 Downstream signal transduction 11/771 29/10654 2.740947740232462e-6 9.670891083461705e-6 4.9719939147546815e-6 5159/5155/6778/3845/6776/6777/6774/6772/6714/6654/2885 11 Vesicular_stomatitis_Indiana_virus R-HSA-199418 Negative regulation of the PI3K/AKT network 23/771 110/10654 2.950197884141502e-6 1.0296890471078252e-5 5.293832421569455e-6 7409/3082/5519/3643/5159/5518/5155/1956/5528/2100/2549/5728/5525/1950/5529/3630/5526/4233/6714/5527/2885/5515/5516 23 Vesicular_stomatitis_Indiana_virus R-HSA-1170546 Prolactin receptor signaling 8/771 15/10654 2.955079083500176e-6 1.0296890471078252e-5 5.293832421569455e-6 8454/6500/8945/3717/6776/6777/9978/2690 8 Vesicular_stomatitis_Indiana_virus R-HSA-5637810 Constitutive Signaling by EGFRvIII 8/771 15/10654 2.955079083500176e-6 1.0296890471078252e-5 5.293832421569455e-6 6464/1956/3845/2549/1950/11140/6654/2885 8 Vesicular_stomatitis_Indiana_virus R-HSA-5637812 Signaling by EGFRvIII in Cancer 8/771 15/10654 2.955079083500176e-6 1.0296890471078252e-5 5.293832421569455e-6 6464/1956/3845/2549/1950/11140/6654/2885 8 Vesicular_stomatitis_Indiana_virus R-HSA-170834 Signaling by TGF-beta Receptor Complex 18/771 73/10654 3.0166297802494072e-6 1.0478819236655836e-5 5.3873655518223084e-6 22938/7514/1025/7311/4088/7040/64750/7316/5501/7321/51377/3065/9958/9040/4738/4609/7314/6233 18 Vesicular_stomatitis_Indiana_virus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 22/771 103/10654 3.3344117154241683e-6 1.1546944273783693e-5 5.936509486850047e-6 7409/3082/5519/3643/5159/5518/5155/1956/5528/2100/2549/5525/1950/5529/3630/5526/4233/6714/5527/2885/5515/5516 22 Vesicular_stomatitis_Indiana_virus R-HSA-5654743 Signaling by FGFR4 13/771 41/10654 3.5515213276681122e-6 1.2260944398903451e-5 6.303590890889477e-6 7311/5518/6464/3845/2549/7316/6714/6654/7314/6233/2885/5515/5516 13 Vesicular_stomatitis_Indiana_virus R-HSA-8848021 Signaling by PTK6 15/771 54/10654 4.097537727046821e-6 1.405944137537166e-5 7.22823329928105e-6 898/1017/7311/3091/2034/1956/3845/5770/7316/595/1950/6774/7314/6233/1027 15 Vesicular_stomatitis_Indiana_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 15/771 54/10654 4.097537727046821e-6 1.405944137537166e-5 7.22823329928105e-6 898/1017/7311/3091/2034/1956/3845/5770/7316/595/1950/6774/7314/6233/1027 15 Vesicular_stomatitis_Indiana_virus R-HSA-8876384 Listeria monocytogenes entry into host cells 9/771 20/10654 4.217974996391749e-6 1.4428560810827874e-5 7.418004807518224e-6 7311/999/7316/1499/4233/6714/7314/6233/2885 9 Vesicular_stomatitis_Indiana_virus R-HSA-8854691 Interleukin-20 family signaling 10/771 25/10654 4.467155688517723e-6 1.5234494475735214e-5 7.832351039218404e-6 3717/6776/6777/6773/7297/6774/6775/3718/6772/3716 10 Vesicular_stomatitis_Indiana_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 14/771 48/10654 4.560233410371855e-6 1.5504793595264305e-5 7.971317093728156e-6 7409/7311/5777/3717/6464/6776/6777/7316/3718/6654/7314/6233/2885/3716 14 Vesicular_stomatitis_Indiana_virus R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 14/771 49/10654 5.964391317751171e-6 2.021766482935593e-5 1.0394296206480018e-5 898/1017/2810/9134/2033/3276/890/7157/8900/983/1026/6790/1027/4869 14 Vesicular_stomatitis_Indiana_virus R-HSA-6807004 Negative regulation of MET activity 9/771 21/10654 6.9093033823791775e-6 2.3350115647679026e-5 1.2004750328293562e-5 3082/7311/5770/7316/5771/4233/7314/6233/2885 9 Vesicular_stomatitis_Indiana_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 20/771 92/10654 6.9711257910623206e-6 2.3488297710426196e-5 1.2075792424536596e-5 672/1017/7311/6119/6118/472/5300/580/6117/7316/84126/890/7157/8900/1457/6790/9212/8148/7314/6233 20 Vesicular_stomatitis_Indiana_virus R-HSA-1227986 Signaling by ERBB2 14/771 50/10654 7.739181004276727e-6 2.599808708622302e-5 1.3366124142274335e-5 7311/8065/6464/1956/3845/2549/7316/1950/11140/6714/6654/7314/6233/2885 14 Vesicular_stomatitis_Indiana_virus R-HSA-5689896 Ovarian tumor domain proteases 12/771 38/10654 8.851920496823005e-6 2.9647327753538542e-5 1.5242270014953675e-5 7311/7187/7706/324/7316/5728/79155/7321/7157/983/7314/6233 12 Vesicular_stomatitis_Indiana_virus R-HSA-209560 NF-kB is activated and signals survival 7/771 13/10654 1.1796854948764145e-5 3.9393069203908846e-5 2.0252745964670275e-5 7311/4790/7316/5970/4792/7314/6233 7 Vesicular_stomatitis_Indiana_virus R-HSA-1980143 Signaling by NOTCH1 17/771 73/10654 1.2903586182371833e-5 4.29609011769175e-5 2.2087038038231345e-5 8454/6500/22938/7311/3091/1387/79885/2033/7316/9978/55869/3065/8650/83737/4609/7314/6233 17 Vesicular_stomatitis_Indiana_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 11/771 34/10654 1.6208401902717474e-5 5.38042217007367e-5 2.7661800818091488e-5 7311/7187/5094/7706/5300/7316/1540/7321/83737/7314/6233 11 Vesicular_stomatitis_Indiana_virus R-HSA-8939211 ESR-mediated signaling 34/771 223/10654 2.5803466070470476e-5 8.540262221553945e-5 4.390715543119957e-5 2962/7514/1025/1387/2963/5437/3838/5441/5434/5440/6464/1956/3169/5438/5431/3845/2033/2100/5435/595/3276/5433/1950/8312/5439/1655/3065/5430/5432/3480/5436/6714/4609/1027 34 Vesicular_stomatitis_Indiana_virus R-HSA-6804760 Regulation of TP53 Activity through Methylation 8/771 19/10654 2.6723547255833553e-5 8.818770594425072e-5 4.533902135045446e-5 7311/472/2033/7316/7157/26013/7314/6233 8 Vesicular_stomatitis_Indiana_virus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 10/771 30/10654 2.9436193719621535e-5 9.685457288391602e-5 4.9794826850910946e-5 7311/6119/6118/6117/8450/7316/9978/7314/6233/8451 10 Vesicular_stomatitis_Indiana_virus R-HSA-9006335 Signaling by Erythropoietin 9/771 25/10654 3.688357524872366e-5 1.2065122865617477e-4 6.202915217523575e-5 7409/3717/6464/3845/6776/2549/6777/6654/2885 9 Vesicular_stomatitis_Indiana_virus R-HSA-937041 IKK complex recruitment mediated by RIP1 9/771 25/10654 3.688357524872366e-5 1.2065122865617477e-4 6.202915217523575e-5 330/7311/23098/11035/329/7316/7321/7314/6233 9 Vesicular_stomatitis_Indiana_virus R-HSA-6806834 Signaling by MET 17/771 79/10654 3.868155385831789e-5 1.261648355495136e-4 6.486380512349511e-5 3082/7311/6464/1289/3845/2549/3688/5770/7316/5771/6774/4233/6714/6654/7314/6233/2885 17 Vesicular_stomatitis_Indiana_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 8/771 20/10654 4.1727262095461534e-5 1.3492215582451827e-4 6.936611444960692e-5 330/7311/11035/329/7316/7321/7314/6233 8 Vesicular_stomatitis_Indiana_virus R-HSA-5213460 RIPK1-mediated regulated necrosis 8/771 20/10654 4.1727262095461534e-5 1.3492215582451827e-4 6.936611444960692e-5 330/7311/11035/329/7186/7316/7314/6233 8 Vesicular_stomatitis_Indiana_virus R-HSA-5218859 Regulated Necrosis 8/771 20/10654 4.1727262095461534e-5 1.3492215582451827e-4 6.936611444960692e-5 330/7311/11035/329/7186/7316/7314/6233 8 Vesicular_stomatitis_Indiana_virus R-HSA-451927 Interleukin-2 family signaling 12/771 44/10654 4.604139532896584e-5 1.4844380907787263e-4 7.631786037590224e-5 5777/3717/6464/6776/6777/6774/6775/3718/6772/6654/2885/3716 12 Vesicular_stomatitis_Indiana_virus R-HSA-8851805 MET activates RAS signaling 6/771 11/10654 4.746674542331962e-5 1.5260082626064356e-4 7.845506406870503e-5 3082/6464/3845/4233/6654/2885 6 Vesicular_stomatitis_Indiana_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 14/771 58/10654 4.861888471382514e-5 1.5409714307602204e-4 7.922434975669396e-5 8454/6500/22938/7311/1387/79885/2033/7316/9978/55869/3065/4609/7314/6233 14 Vesicular_stomatitis_Indiana_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 14/771 58/10654 4.861888471382514e-5 1.5409714307602204e-4 7.922434975669396e-5 8454/6500/22938/7311/1387/79885/2033/7316/9978/55869/3065/4609/7314/6233 14 Vesicular_stomatitis_Indiana_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 14/771 58/10654 4.861888471382514e-5 1.5409714307602204e-4 7.922434975669396e-5 8454/6500/22938/7311/1387/79885/2033/7316/9978/55869/3065/4609/7314/6233 14 Vesicular_stomatitis_Indiana_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 14/771 58/10654 4.861888471382514e-5 1.5409714307602204e-4 7.922434975669396e-5 8454/6500/22938/7311/1387/79885/2033/7316/9978/55869/3065/4609/7314/6233 14 Vesicular_stomatitis_Indiana_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 14/771 58/10654 4.861888471382514e-5 1.5409714307602204e-4 7.922434975669396e-5 8454/6500/22938/7311/1387/79885/2033/7316/9978/55869/3065/4609/7314/6233 14 Vesicular_stomatitis_Indiana_virus R-HSA-5696394 DNA Damage Recognition in GG-NER 11/771 38/10654 5.2165622771985795e-5 1.6487275704272692e-4 8.476430327367893e-5 7311/5887/8450/7316/9978/10987/5886/7314/6233/8451/10980 11 Vesicular_stomatitis_Indiana_virus R-HSA-110312 Translesion synthesis by REV1 7/771 16/10654 6.483535817374054e-5 2.037682685460417e-4 1.0476124511045209e-4 7311/6119/6118/6117/7316/7314/6233 7 Vesicular_stomatitis_Indiana_virus R-HSA-193639 p75NTR signals via NF-kB 7/771 16/10654 6.483535817374054e-5 2.037682685460417e-4 1.0476124511045209e-4 7311/4790/7316/5970/4792/7314/6233 7 Vesicular_stomatitis_Indiana_virus R-HSA-9018519 Estrogen-dependent gene expression 25/771 150/10654 6.915353147325266e-5 2.167325762932667e-4 1.1142644883076291e-4 2962/1025/1387/2963/5437/3838/5441/5434/5440/3169/5438/5431/2033/5435/595/3276/5433/8312/5439/1655/3065/5430/5432/5436/4609 25 Vesicular_stomatitis_Indiana_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 10/771 33/10654 7.430800345203146e-5 2.3223838404785318e-4 1.1939828732359842e-4 7311/351/4790/7316/5970/4792/4793/4791/7314/6233 10 Vesicular_stomatitis_Indiana_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 20/771 108/10654 8.13850860924035e-5 2.536501849879909e-4 1.304065122182372e-4 3082/7124/3091/3717/6778/7040/4843/3688/595/3312/7297/6774/7157/1026/3718/7422/7133/6772/4609/3716 20 Vesicular_stomatitis_Indiana_virus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 17/771 84/10654 8.783648147313769e-5 2.7299870419074927e-4 1.403539636893992e-4 404672/7311/6119/6118/5887/6117/8450/7316/9978/10987/7329/5886/7314/6233/8451/8554/10980 17 Vesicular_stomatitis_Indiana_virus R-HSA-5689877 Josephin domain DUBs 6/771 12/10654 8.912598317905023e-5 2.7548031164433706e-4 1.4162980653072214e-4 7311/5887/7316/5886/7314/6233 6 Vesicular_stomatitis_Indiana_virus R-HSA-8984722 Interleukin-35 Signalling 6/771 12/10654 8.912598317905023e-5 2.7548031164433706e-4 1.4162980653072214e-4 3717/7297/6774/6775/6772/3716 6 Vesicular_stomatitis_Indiana_virus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 7/771 17/10654 1.033639454442618e-4 3.168697999684747e-4 1.6290895054200594e-4 11035/4790/1660/5970/4792/4793/4791 7 Vesicular_stomatitis_Indiana_virus R-HSA-5655862 Translesion synthesis by POLK 7/771 17/10654 1.033639454442618e-4 3.168697999684747e-4 1.6290895054200594e-4 7311/6119/6118/6117/7316/7314/6233 7 Vesicular_stomatitis_Indiana_virus R-HSA-5656121 Translesion synthesis by POLI 7/771 17/10654 1.033639454442618e-4 3.168697999684747e-4 1.6290895054200594e-4 7311/6119/6118/6117/7316/7314/6233 7 Vesicular_stomatitis_Indiana_virus R-HSA-5696400 Dual Incision in GG-NER 11/771 41/10654 1.1210393795076946e-4 3.42726480601535e-4 1.762023748659735e-4 404672/7311/6119/6118/6117/8450/7316/9978/7314/6233/8451 11 Vesicular_stomatitis_Indiana_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 13/771 55/10654 1.1350765136114568e-4 3.4607495876958004e-4 1.7792389286586913e-4 330/7311/329/351/4790/7316/1540/5608/5970/83737/4791/7314/6233 13 Vesicular_stomatitis_Indiana_virus R-HSA-388841 Costimulation by the CD28 family 15/771 70/10654 1.1488030455310788e-4 3.4931084473871824e-4 1.795875250181233e-4 7409/5519/5777/5518/5528/5525/5529/9020/5526/5062/6714/5527/2885/5515/5516 15 Vesicular_stomatitis_Indiana_virus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 8/771 23/10654 1.3360261516641764e-4 4.0514090328843403e-4 2.0829084811151317e-4 7311/4088/64750/7316/7321/3065/7314/6233 8 Vesicular_stomatitis_Indiana_virus R-HSA-5654732 Negative regulation of FGFR3 signaling 9/771 29/10654 1.3897933859850306e-4 4.2030948223051334e-4 2.1608931068798322e-4 7311/5518/7316/6714/7314/6233/2885/5515/5516 9 Vesicular_stomatitis_Indiana_virus R-HSA-177929 Signaling by EGFR 12/771 49/10654 1.4398091152302556e-4 4.3310075798615194e-4 2.2266555528324542e-4 7311/6464/1956/3845/2549/7316/1950/6714/6654/7314/6233/2885 12 Vesicular_stomatitis_Indiana_virus R-HSA-9012852 Signaling by NOTCH3 12/771 49/10654 1.4398091152302556e-4 4.3310075798615194e-4 2.2266555528324542e-4 22938/7311/1387/1956/2033/7316/1950/4904/6772/7314/6233/11060 12 Vesicular_stomatitis_Indiana_virus R-HSA-5675482 Regulation of necroptotic cell death 7/771 18/10654 1.5863137915396753e-4 4.7589413746190257e-4 2.446664671443125e-4 330/7311/329/7186/7316/7314/6233 7 Vesicular_stomatitis_Indiana_virus R-HSA-447115 Interleukin-12 family signaling 13/771 57/10654 1.6735661085301787e-4 5.007309796722294e-4 2.574355726244317e-4 3717/9987/6627/3458/3181/7297/3185/6774/5062/6775/5721/6772/3716 13 Vesicular_stomatitis_Indiana_virus R-HSA-1433557 Signaling by SCF-KIT 11/771 43/10654 1.786140420066327e-4 5.329919019453241e-4 2.740215426081599e-4 7409/5777/3717/3845/6776/6777/6774/6772/6714/6654/2885 11 Vesicular_stomatitis_Indiana_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 9/771 30/10654 1.859264006894525e-4 5.518767766496447e-4 2.8373062539075464e-4 7124/330/7311/329/7186/7316/1540/7314/6233 9 Vesicular_stomatitis_Indiana_virus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 9/771 30/10654 1.859264006894525e-4 5.518767766496447e-4 2.8373062539075464e-4 7311/11065/7316/7319/7874/7321/7324/7314/6233 9 Vesicular_stomatitis_Indiana_virus R-HSA-933542 TRAF6 mediated NF-kB activation 8/771 24/10654 1.8779709064610053e-4 5.544956202761179e-4 2.850770240278756e-4 351/7706/7186/4790/5970/4792/4793/4791 8 Vesicular_stomatitis_Indiana_virus R-HSA-982772 Growth hormone receptor signaling 8/771 24/10654 1.8779709064610053e-4 5.544956202761179e-4 2.850770240278756e-4 5777/3717/6776/6777/5770/2690/6774/6772 8 Vesicular_stomatitis_Indiana_virus R-HSA-5693607 Processing of DNA double-strand break ends 18/771 98/10654 2.03003055383757e-4 5.978200213663396e-4 3.073509444682935e-4 672/1017/7158/7311/6119/6118/472/580/6117/7316/84126/890/8900/7329/8924/51588/7314/6233 18 Vesicular_stomatitis_Indiana_virus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 11/771 44/10654 2.2280492423252027e-4 6.544165575625334e-4 3.3644832868399315e-4 22938/1025/7311/4088/64750/7316/7321/3065/4609/7314/6233 11 Vesicular_stomatitis_Indiana_virus R-HSA-110320 Translesion Synthesis by POLH 7/771 19/10654 2.3557761442787847e-4 6.901255440942028e-4 3.5480701582101806e-4 7311/6119/6118/6117/7316/7314/6233 7 Vesicular_stomatitis_Indiana_virus R-HSA-5654733 Negative regulation of FGFR4 signaling 9/771 31/10654 2.453534175219584e-4 7.168920168219721e-4 3.6856818202311734e-4 7311/5518/7316/6714/7314/6233/2885/5515/5516 9 Vesicular_stomatitis_Indiana_virus R-HSA-174490 Membrane binding and targetting of GAG proteins 6/771 14/10654 2.5537317540606026e-4 7.384760381587619e-4 3.796649487860039e-4 7311/55048/7251/7316/7314/6233 6 Vesicular_stomatitis_Indiana_virus R-HSA-174495 Synthesis And Processing Of GAG, GAGPOL Polyproteins 6/771 14/10654 2.5537317540606026e-4 7.384760381587619e-4 3.796649487860039e-4 7311/55048/7251/7316/7314/6233 6 Vesicular_stomatitis_Indiana_virus R-HSA-180336 SHC1 events in EGFR signaling 6/771 14/10654 2.5537317540606026e-4 7.384760381587619e-4 3.796649487860039e-4 6464/1956/3845/1950/6654/2885 6 Vesicular_stomatitis_Indiana_virus R-HSA-9027284 Erythropoietin activates RAS 6/771 14/10654 2.5537317540606026e-4 7.384760381587619e-4 3.796649487860039e-4 7409/3717/6464/3845/6654/2885 6 Vesicular_stomatitis_Indiana_virus R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus 8/771 25/10654 2.5881521553898474e-4 7.465055831227271e-4 3.837930946160564e-4 7311/1956/7316/1950/4904/7314/6233/11060 8 Vesicular_stomatitis_Indiana_virus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 10/771 38/10654 2.7254756128634926e-4 7.840983686238048e-4 4.031202795814289e-4 51741/1387/1956/2033/1026/7329/7422/4609/3329/4869 10 Vesicular_stomatitis_Indiana_virus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 9/771 32/10654 3.197052308660399e-4 9.17415010311245e-4 4.7166096786805734e-4 22938/1025/7311/4088/7316/3065/4609/7314/6233 9 Vesicular_stomatitis_Indiana_virus R-HSA-9006936 Signaling by TGF-beta family members 18/771 102/10654 3.4013697512978345e-4 9.735553216724923e-4 5.005237979890477e-4 22938/7514/1025/7311/4088/7040/64750/7316/5501/7321/51377/3065/9958/9040/4738/4609/7314/6233 18 Vesicular_stomatitis_Indiana_virus R-HSA-2465910 MASTL Facilitates Mitotic Progression 5/771 10/10654 3.631889866534945e-4 0.0010342589924497991 5.317327402781591e-4 5519/5518/983/5515/5516 5 Vesicular_stomatitis_Indiana_virus R-HSA-74749 Signal attenuation 5/771 10/10654 3.631889866534945e-4 0.0010342589924497991 5.317327402781591e-4 3643/6464/3630/6654/2885 5 Vesicular_stomatitis_Indiana_virus R-HSA-430039 mRNA decay by 5' to 3' exoribonuclease 6/771 15/10654 3.996941093042989e-4 0.001132466643028847 5.822232107888246e-4 51690/23658/11157/57819/27258/25804 6 Vesicular_stomatitis_Indiana_virus R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 6/771 15/10654 3.996941093042989e-4 0.001132466643028847 5.822232107888246e-4 7311/7316/4233/7314/6233/2885 6 Vesicular_stomatitis_Indiana_virus R-HSA-5357905 Regulation of TNFR1 signaling 9/771 33/10654 4.11729191146293e-4 0.0011607039006686953 5.967405362289569e-4 7124/330/7311/329/7186/7316/1540/7314/6233 9 Vesicular_stomatitis_Indiana_virus R-HSA-5654726 Negative regulation of FGFR1 signaling 9/771 33/10654 4.11729191146293e-4 0.0011607039006686953 5.967405362289569e-4 7311/5518/7316/6714/7314/6233/2885/5515/5516 9 Vesicular_stomatitis_Indiana_virus R-HSA-9020591 Interleukin-12 signaling 11/771 47/10654 4.1444009125298723e-4 0.0011654180009670469 5.991641472276402e-4 3717/9987/6627/3458/3181/7297/3185/5062/6775/5721/3716 11 Vesicular_stomatitis_Indiana_virus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 7/771 21/10654 4.783610109508611e-4 0.001338456494480963 6.881266150441578e-4 11035/4790/1660/5970/4792/4793/4791 7 Vesicular_stomatitis_Indiana_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 7/771 21/10654 4.783610109508611e-4 0.001338456494480963 6.881266150441578e-4 5971/1387/4790/3845/2033/5970/5062 7 Vesicular_stomatitis_Indiana_virus R-HSA-73893 DNA Damage Bypass 11/771 48/10654 5.030876536715156e-4 0.001404140167710051 7.218958738203472e-4 7311/6119/6118/7706/6117/8450/7316/9978/7314/6233/8451 11 Vesicular_stomatitis_Indiana_virus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 16/771 88/10654 5.073510819056025e-4 0.0014125258409381787 7.262071121438427e-4 8454/6500/7311/8945/5518/5347/23291/7316/5108/983/84962/6790/4751/7314/5577/6233 16 Vesicular_stomatitis_Indiana_virus R-HSA-5654727 Negative regulation of FGFR2 signaling 9/771 34/10654 5.244858784838318e-4 0.0014566167219278693 7.488750948648771e-4 7311/5518/7316/6714/7314/6233/2885/5515/5516 9 Vesicular_stomatitis_Indiana_virus R-HSA-175474 Assembly Of The HIV Virion 6/771 16/10654 6.006093599826352e-4 0.0016639103750630039 8.554488090201015e-4 7311/55048/7251/7316/7314/6233 6 Vesicular_stomatitis_Indiana_virus R-HSA-1059683 Interleukin-6 signaling 5/771 11/10654 6.262908543453069e-4 0.001722299849449594 8.854679777637466e-4 3717/7297/6774/6772/3716 5 Vesicular_stomatitis_Indiana_virus R-HSA-4755510 SUMOylation of immune response proteins 5/771 11/10654 6.262908543453069e-4 0.001722299849449594 8.854679777637466e-4 5970/4792/7329/4791/51588 5 Vesicular_stomatitis_Indiana_virus R-HSA-9020956 Interleukin-27 signaling 5/771 11/10654 6.262908543453069e-4 0.001722299849449594 8.854679777637466e-4 3717/7297/6774/6772/3716 5 Vesicular_stomatitis_Indiana_virus R-HSA-9613829 Chaperone Mediated Autophagy 7/771 22/10654 6.582021770371361e-4 0.0018054566356832218 9.282205050702747e-4 1080/7311/7316/3312/1915/7314/6233 7 Vesicular_stomatitis_Indiana_virus R-HSA-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle 9/771 35/10654 6.613571098625705e-4 0.0018054566356832218 9.282205050702747e-4 7311/5887/84447/7316/5700/267/79139/7314/6233 9 Vesicular_stomatitis_Indiana_virus R-HSA-9615710 Microautophagy 9/771 35/10654 6.613571098625705e-4 0.0018054566356832218 9.282205050702747e-4 1080/7311/55048/7251/128866/7316/3312/7314/6233 9 Vesicular_stomatitis_Indiana_virus R-HSA-186797 Signaling by PDGF 12/771 58/10654 7.62260785512386e-4 0.002075865537244896 0.0010672430006662941 5159/5155/1289/6778/3845/6776/6777/6774/6772/6714/6654/2885 12 Vesicular_stomatitis_Indiana_virus R-HSA-5205647 Mitophagy 8/771 29/10654 7.927310223682745e-4 0.0021484159591719904 0.0011045425890104615 9804/7311/7416/7316/1457/6714/7314/6233 8 Vesicular_stomatitis_Indiana_virus R-HSA-8863795 Downregulation of ERBB2 signaling 8/771 29/10654 7.927310223682745e-4 0.0021484159591719904 0.0011045425890104615 7311/8065/1956/7316/1950/11140/7314/6233 8 Vesicular_stomatitis_Indiana_virus R-HSA-168638 NOD1/2 Signaling Pathway 9/771 36/10654 8.260510388769743e-4 0.0022333235316143738 0.001148195229688223 330/7311/329/7316/1540/5608/83737/7314/6233 9 Vesicular_stomatitis_Indiana_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 5/771 12/10654 0.00100998004803549 0.002710999076305789 0.001393777553068367 7311/7187/7316/7314/6233 5 Vesicular_stomatitis_Indiana_virus R-HSA-9020558 Interleukin-2 signaling 5/771 12/10654 0.00100998004803549 0.002710999076305789 0.001393777553068367 6464/6776/6777/3718/3716 5 Vesicular_stomatitis_Indiana_virus R-HSA-9634600 Regulation of glycolysis by fructose 2,6-bisphosphate metabolism 5/771 12/10654 0.00100998004803549 0.002710999076305789 0.001393777553068367 5519/5518/5528/5515/5516 5 Vesicular_stomatitis_Indiana_virus R-HSA-176187 Activation of ATR in response to replication stress 9/771 37/10654 0.0010226042003452882 0.0027383339207336832 0.0014078309302580528 4998/1017/6119/6118/6117/990/84126/993/4171 9 Vesicular_stomatitis_Indiana_virus R-HSA-75153 Apoptotic execution phase 11/771 52/10654 0.0010314492270641889 0.0027554429351571903 0.0014166270085994375 4000/1828/329/3837/999/100506658/324/1499/4137/5062/3836 11 Vesicular_stomatitis_Indiana_virus R-HSA-194315 Signaling by Rho GTPases 51/771 455/10654 0.001096929861755781 0.002923409275273127 0.0015029817833283362 701/1894/7409/1857/7514/5519/1080/2810/9184/5905/348995/4928/79023/5518/3799/81929/57122/6280/5903/5347/999/5300/6396/5528/3688/1499/25936/5525/80776/5501/5529/25909/991/1856/5526/4085/5062/55746/80152/9212/6714/23279/6654/54763/5527/1855/2885/5515/1027/79902/5516 51 Vesicular_stomatitis_Indiana_virus R-HSA-5693606 DNA Double Strand Break Response 14/771 77/10654 0.001115961411222442 0.0029670822355250706 0.0015254349048388581 672/7158/7311/3838/472/580/5599/7316/7157/7329/8924/51588/7314/6233 14 Vesicular_stomatitis_Indiana_virus R-HSA-3899300 SUMOylation of transcription cofactors 10/771 45/10654 0.001159341115171994 0.0030751317523001827 0.001580985270907684 1387/6294/2033/57332/1655/7329/6045/51588/8554/4869 10 Vesicular_stomatitis_Indiana_virus R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 6/771 18/10654 0.0012284355077465448 0.003235456900684562 0.0016634115597852894 2810/2033/3276/7157/983/6790 6 Vesicular_stomatitis_Indiana_virus R-HSA-73780 RNA Polymerase III Chain Elongation 6/771 18/10654 0.0012284355077465448 0.003235456900684562 0.0016634115597852894 5437/5441/5434/5440/5435/9533 6 Vesicular_stomatitis_Indiana_virus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 6/771 18/10654 0.0012284355077465448 0.003235456900684562 0.0016634115597852894 7311/23098/7187/7316/7314/6233 6 Vesicular_stomatitis_Indiana_virus R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 7/771 25/10654 0.0015325659794154889 0.0040270234868950315 0.002070371395833078 7311/6119/6118/6117/7316/7314/6233 7 Vesicular_stomatitis_Indiana_virus R-HSA-179812 GRB2 events in EGFR signaling 5/771 13/10654 0.0015440875198759689 0.004038382744290995 0.0020762114118317533 1956/3845/1950/6654/2885 5 Vesicular_stomatitis_Indiana_virus R-HSA-202670 ERKs are inactivated 5/771 13/10654 0.0015440875198759689 0.004038382744290995 0.0020762114118317533 5519/5518/5528/5515/5516 5 Vesicular_stomatitis_Indiana_virus R-HSA-5656169 Termination of translesion DNA synthesis 8/771 32/10654 0.001600804190363875 0.004167290722942616 0.0021424855203795424 7311/6119/6118/7706/6117/7316/7314/6233 8 Vesicular_stomatitis_Indiana_virus R-HSA-73863 RNA Polymerase I Transcription Termination 8/771 32/10654 0.001600804190363875 0.004167290722942616 0.0021424855203795424 404672/5437/5441/5434/5440/64425/5435/9533 8 West_Nile_virus R-HSA-72163 mRNA Splicing - Major Pathway 177/1715 183/10654 2.6092938998950904e-134 3.439049360061729e-131 1.5133904619391525e-131 10450/7536/10921/8449/22827/23451/53981/2963/6635/5434/5440/6633/220988/6432/8683/51691/6431/10084/6430/6632/51340/10283/6627/24148/6936/10946/83443/27339/11051/9129/55696/23350/5430/79869/4904/5436/9879/51639/51585/10523/6428/11325/9128/57703/27258/3184/8106/25804/51690/29894/27238/55749/11017/51503/3178/6637/199746/23450/5441/3183/5438/85313/5431/9092/55110/54883/5093/22794/81608/5435/10594/4686/9785/8189/23398/6625/5433/10713/51645/11338/1655/9343/3185/4116/3190/1477/10978/9416/65109/6626/11157/5546/22826/285755/6429/1478/10772/24144/57819/10181/2962/10898/22938/988/10236/5437/10250/6629/4670/23020/10569/23658/10189/6434/51362/9295/10465/84844/6631/10949/51692/55660/3181/5439/10421/11193/51729/1660/25949/23283/9939/2521/3191/10285/9410/6638/57794/27316/6636/3187/1993/1665/10286/23524/56949/53938/6634/10914/5094/51593/9775/3192/9716/8896/6427/3312/8175/5356/6426/84950/57461/3188/84991/10907/10291/5432/22916/56259/5725/1479/26121/11100/10992/55339/10262/6628/1994 177 West_Nile_virus R-HSA-72172 mRNA Splicing 177/1715 191/10654 9.299632781048851e-125 6.128458002711193e-122 2.6968935065041667e-122 10450/7536/10921/8449/22827/23451/53981/2963/6635/5434/5440/6633/220988/6432/8683/51691/6431/10084/6430/6632/51340/10283/6627/24148/6936/10946/83443/27339/11051/9129/55696/23350/5430/79869/4904/5436/9879/51639/51585/10523/6428/11325/9128/57703/27258/3184/8106/25804/51690/29894/27238/55749/11017/51503/3178/6637/199746/23450/5441/3183/5438/85313/5431/9092/55110/54883/5093/22794/81608/5435/10594/4686/9785/8189/23398/6625/5433/10713/51645/11338/1655/9343/3185/4116/3190/1477/10978/9416/65109/6626/11157/5546/22826/285755/6429/1478/10772/24144/57819/10181/2962/10898/22938/988/10236/5437/10250/6629/4670/23020/10569/23658/10189/6434/51362/9295/10465/84844/6631/10949/51692/55660/3181/5439/10421/11193/51729/1660/25949/23283/9939/2521/3191/10285/9410/6638/57794/27316/6636/3187/1993/1665/10286/23524/56949/53938/6634/10914/5094/51593/9775/3192/9716/8896/6427/3312/8175/5356/6426/84950/57461/3188/84991/10907/10291/5432/22916/56259/5725/1479/26121/11100/10992/55339/10262/6628/1994 177 West_Nile_virus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 198/1715 244/10654 3.853544416251211e-115 1.6929905135396985e-112 7.450185871419008e-113 10450/7536/10921/8449/23165/22827/23451/53981/7919/4928/2963/81929/6635/5434/5440/6633/220988/6432/8683/51691/6431/10084/6430/6632/51340/10283/6627/55706/7175/24148/6936/10946/9631/83443/27339/11051/9129/55696/23350/5430/79869/4904/5436/9879/51639/51585/10523/6428/11325/9128/57703/27258/3184/8106/25804/51690/29894/27238/9589/55749/11017/51503/3178/6637/199746/23450/79023/57122/5441/3183/5438/85313/5431/9092/55110/54883/5093/22794/81608/5435/10594/4686/9785/8189/23398/6625/5433/10713/51645/11338/1655/9343/3185/4116/3190/1477/10978/9416/65109/6626/56339/11157/5546/22826/285755/6429/1478/10772/24144/57819/10181/9688/2962/10898/22938/988/10236/9984/5437/10250/6629/4670/23020/10569/26097/23658/10189/6434/51362/9295/10465/84844/6631/10482/10949/51692/55660/3181/5439/10421/11193/51729/1660/25949/23283/8086/9939/2521/1977/3191/10285/9410/6638/57794/57721/27316/6636/3187/1993/1665/10286/23524/56949/53938/6634/10914/5094/51593/9775/3192/9716/6396/8896/6427/79228/3312/8175/5356/2733/6426/84950/57461/3188/84991/10907/10291/5432/22916/56259/5725/1479/26121/11100/10992/55339/10262/6628/1994 198 West_Nile_virus R-HSA-5684996 MAPK1/MAPK3 signaling 200/1715 255/10654 5.185599380172693e-111 1.7086549957669023e-108 7.519119101250405e-109 5923/5718/22821/818/5786/5689/10156/815/9462/1839/5684/2674/3562/4893/6464/6711/685/1437/3667/71/8823/6712/5682/5604/8831/2904/2065/3561/5525/5747/153090/3815/283455/5526/8844/10048/817/3674/7094/84292/5690/7010/1439/5594/2069/2322/5717/2675/8074/409/5908/3082/7414/3568/8817/10817/2064/5921/10197/4902/1438/2260/8452/54518/5528/4684/2254/2902/7316/10213/10125/673/152831/9978/1950/3560/2676/8315/221002/2263/4233/983/3718/2668/57731/22866/2249/25780/26281/6714/5605/10818/64926/6710/5037/2248/5519/5711/64096/8437/10256/2261/5159/3567/5687/3558/5922/3717/2247/5685/2244/2255/54756/5708/53358/145957/3084/5692/5686/2335/2534/3690/408/9965/5529/1445/2264/816/5702/4296/2066/6708/27006/5894/5719/3563/5979/1741/2906/9693/1742/6654/9542/1739/6233/5527/2885/10718/6709/51332/3716/88/2266/8660/2246/7311/8826/5906/2251/115727/5518/5155/2243/9048/7450/2252/1956/1740/60/5536/399473/4140/3845/5623/5694/3265/3559/369/801/200734/4763/7297/5781/3569/5693/5924/5691/4747/5245/2323/7529/5156/7314/3572/161742/5595/25759/5515/284/5516 200 West_Nile_virus R-HSA-9607240 FLT3 Signaling 204/1715 267/10654 2.592037400304189e-109 6.832610587201843e-107 3.006763384352859e-107 5295/54106/5923/5718/22821/818/5786/5689/10156/815/9462/1839/5684/2674/3562/4893/6464/6711/685/5290/1437/3667/71/8823/6712/5682/5291/5604/8831/2904/2065/3561/5525/5747/153090/3815/283455/5526/8844/10048/817/3674/7094/84292/5690/7010/1439/5594/2069/2322/5717/2675/8074/409/5908/3082/7414/3568/8817/10817/2064/5921/10197/4902/1438/2260/8452/54518/5528/4684/2254/2902/7316/10213/10125/673/152831/9978/1950/3560/2676/8315/221002/2263/4233/3055/3718/2668/57731/22866/2249/25780/26281/6714/5605/10818/64926/6710/5037/2248/5519/5711/64096/8437/10256/2261/5159/3567/5687/3558/5922/3717/2247/5685/2244/2255/54756/5708/53358/145957/3084/5692/5686/2335/2534/3690/408/9965/5529/1445/2264/816/5702/4296/2066/6708/27006/5894/5719/3563/5979/1741/2906/9693/1742/6654/9542/1739/6233/5527/2885/10718/6709/51332/3716/88/2266/8660/2246/7311/8826/5906/2251/9846/115727/5518/5155/2243/9048/7450/2252/1956/1740/60/5536/5296/399473/4140/3845/2549/5623/5694/3265/3559/369/801/200734/4763/5781/5693/5924/5691/4747/5245/2323/7529/5156/7314/161742/5595/25759/5515/284/5516 204 West_Nile_virus R-HSA-5673001 RAF/MAP kinase cascade 195/1715 249/10654 5.928538600090271e-108 1.3023023124864962e-105 5.730920646753929e-106 5923/5718/22821/818/5786/5689/10156/815/9462/1839/5684/2674/3562/4893/6464/6711/685/1437/3667/71/8823/6712/5682/5604/8831/2904/2065/3561/5525/5747/153090/3815/283455/5526/8844/10048/817/3674/7094/84292/5690/7010/1439/5594/2069/2322/5717/2675/8074/409/5908/3082/7414/3568/8817/10817/2064/5921/10197/4902/1438/2260/8452/54518/5528/4684/2254/2902/7316/10213/10125/673/152831/9978/1950/3560/2676/8315/221002/2263/4233/3718/2668/57731/22866/2249/25780/26281/6714/5605/10818/64926/6710/5037/2248/5519/5711/64096/8437/10256/2261/5159/3567/5687/3558/5922/3717/2247/5685/2244/2255/54756/5708/53358/145957/3084/5692/5686/2335/2534/3690/408/9965/5529/1445/2264/816/5702/4296/2066/6708/27006/5894/5719/3563/5979/1741/2906/9693/1742/6654/9542/1739/6233/5527/2885/10718/6709/51332/3716/88/2266/8660/2246/7311/8826/5906/2251/115727/5518/5155/2243/9048/7450/2252/1956/1740/60/5536/399473/4140/3845/5623/5694/3265/3559/369/801/200734/4763/5693/5924/5691/4747/5245/2323/7529/5156/7314/161742/5595/25759/5515/284/5516 195 West_Nile_virus R-HSA-5683057 MAPK family signaling cascades 210/1715 294/10654 8.894467885416306e-103 1.674701238996956e-100 7.369701962202082e-101 5923/5718/22821/818/5786/5689/3725/10156/815/9462/1839/5684/2674/3562/4893/6464/6711/685/1437/3667/71/8823/6712/5682/5604/8831/2904/2065/3561/5525/5747/153090/3815/283455/5526/8844/10048/817/3674/7094/84292/5690/7010/1439/5594/2069/2322/5717/2675/8074/3315/409/5908/3082/7414/3568/8817/10817/2064/5921/10197/4902/1438/2260/8452/54518/5528/4684/2254/2902/7316/10213/10125/673/152831/9978/1950/3560/2676/8315/221002/2263/4233/983/3718/2668/57731/22866/2249/25780/26281/6714/5605/4609/10818/64926/6710/5037/2248/5519/5711/64096/8437/10256/2261/5159/3567/5687/3558/5922/3717/2247/5685/2244/2255/54756/5708/53358/145957/3084/5692/5686/2335/5063/2534/3690/408/9965/5529/1445/2264/816/5702/4296/998/2066/6708/27006/5894/5719/3563/5979/1741/2906/9693/1742/6654/9542/1739/6233/5527/2885/10718/6709/51332/3716/88/2266/8660/2246/7514/7311/8826/5906/2251/115727/5518/5155/2243/9048/7450/2252/1956/1740/60/5536/399473/4140/4343/3845/5623/5694/3265/3559/369/5058/801/200734/4763/7297/5781/3569/5062/5693/5924/5691/4747/5245/2323/7529/5156/7314/3572/5879/161742/5595/25759/5515/284/5516 210 West_Nile_virus R-HSA-5663202 Diseases of signal transduction 213/1715 377/10654 4.148570636729305e-75 6.834770124011529e-73 3.007713711628746e-73 5295/8454/4000/5718/27044/818/5689/2963/815/8805/5434/5440/1839/5684/22906/4893/11052/6464/685/5290/3667/71/79718/8087/8823/5682/5291/5604/1499/2065/10018/5525/10142/842/55750/3815/283455/5430/5526/8844/23462/817/207/3674/5436/7094/1452/5690/5594/2069/9530/5717/8074/409/5908/3082/7414/8817/10533/55109/2064/5441/23164/6199/10197/2260/54845/5438/5431/54518/5528/2100/5435/84447/2254/4686/7316/10213/673/152831/9978/5433/1950/8546/8315/6774/2263/4233/102/1026/57085/22866/2249/6772/26281/6714/2099/5605/4609/10818/4089/10014/2962/22938/5037/2248/5519/9061/8850/8503/5711/80853/10256/2261/1387/5437/5159/5687/3717/10827/2247/5685/2244/2255/3164/5708/145957/3320/3084/5692/5686/2335/2534/2033/3690/408/9965/55294/5728/5529/1445/5439/2264/816/5702/4296/2066/27006/5894/5719/6654/9542/6233/5527/2885/10718/79109/2475/2266/56829/8660/2246/4040/7311/79412/8826/5906/2251/9846/3932/2931/5293/5518/5155/2243/7450/2252/6469/1956/11160/60/5296/1185/4140/9444/3845/2549/5694/3265/369/801/9715/4763/5781/4851/5432/22916/5693/5663/7750/11140/5691/5245/7529/5156/7314/5879/57670/253260/5595/4193/5515/5516 213 West_Nile_virus R-HSA-6802957 Oncogenic MAPK signaling 68/1715 71/10654 1.281607077048068e-50 1.8768423639437265e-48 8.259245607643105e-49 4000/27044/818/815/8805/22906/4893/71/8087/5604/10018/10142/55750/283455/8844/817/3674/7094/5594/409/5908/7414/10533/55109/23164/54845/54518/673/8546/8315/57085/22866/6714/5605/5037/9061/80853/10256/3717/10827/2244/2335/3690/408/1445/816/4296/5894/2266/56829/8826/5906/2243/7450/60/1185/4140/9444/3845/3265/369/801/9715/4763/5245/7529/57670/5595 68 West_Nile_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 210/1715 473/10654 1.8561300650103119e-50 2.4463794256835912e-48 1.076555437705981e-48 5295/54106/4908/5777/627/1173/2963/3643/9402/5434/5440/5590/1839/9252/4893/8065/6464/685/5290/23543/3667/71/5899/8823/5579/23768/5770/4915/5291/1495/5604/1499/2904/2065/6461/5747/3815/5430/10048/207/5436/9550/7422/10458/5578/9114/5594/2069/2322/7074/1785/8074/3315/5908/3082/3178/8817/10817/2064/382/5921/5441/2260/54845/5438/5431/5528/5435/3688/2254/4686/7316/673/152831/1500/5433/1950/51072/527/3185/6774/2263/57498/4233/102/10768/10413/2249/6772/26281/6714/2099/8651/5605/10818/26052/2962/1281/2248/5519/5898/1003/3673/8503/5795/2261/10163/5437/5159/4670/4067/3717/4909/2247/245972/4914/2255/55824/53358/145957/3320/3084/23767/55845/2335/5063/2534/9475/3690/9965/64759/6195/3728/8471/1445/5439/1111/2264/5603/533/998/2066/83737/27006/1742/6654/9542/200958/6233/2885/7525/3187/10718/79109/5580/2475/5900/8660/2246/23191/6093/7073/6196/7311/5906/2251/9846/57610/3932/5518/5155/23163/387/2252/53834/1956/60/5296/5581/6197/3845/2549/3265/5058/801/200734/5781/8877/5062/5432/3480/22916/5663/5725/11140/51231/4916/2323/7529/51382/5156/7314/5879/253260/161742/5595/25759/5515/25920/5516 210 West_Nile_virus R-HSA-6802952 Signaling by BRAF and RAF fusions 64/1715 67/10654 1.8228116597862336e-47 2.184059788725687e-45 9.611188751600141e-46 4000/27044/818/815/8805/22906/4893/71/8087/5604/10018/10142/55750/283455/8844/817/3674/7094/5594/409/5908/7414/10533/55109/23164/54845/54518/673/8546/57085/22866/6714/5605/5037/9061/80853/10256/3717/10827/2244/2335/3690/408/1445/816/5894/2266/56829/8826/5906/2243/7450/60/1185/4140/9444/3845/3265/369/801/9715/7529/57670/5595 64 West_Nile_virus R-HSA-190236 Signaling by FGFR 71/1715 87/10654 1.1491898960438627e-41 1.2621935691548425e-39 5.5544178308786695e-40 5295/2963/5434/5440/4893/6464/5290/23543/8823/23768/5430/5436/5594/8074/3178/8817/10817/5441/2260/54845/5438/5431/5435/2254/4686/7316/673/152831/5433/3185/2263/2249/26281/6714/10818/2962/2248/2261/5437/4670/2247/2255/23767/9965/5439/2264/27006/6654/6233/2885/3187/2246/7073/7311/2251/5518/2252/53834/3845/2549/3265/200734/5781/5432/22916/5725/7314/161742/5595/5515/5516 71 West_Nile_virus R-HSA-9006925 Intracellular signaling by second messengers 144/1715 305/10654 2.8821943080660445e-38 2.922101613870036e-36 1.285902075906389e-36 5295/5718/818/5689/3725/815/3643/3838/1839/5684/685/5305/5290/3667/8823/5682/5291/2065/5525/842/3815/2146/5526/817/207/6045/5690/5578/5594/2069/5717/8074/3082/1460/112/8817/114/2064/6199/10197/2260/4615/5573/5528/2100/2254/7316/10213/152831/1950/2263/1457/4233/1026/10768/2249/26281/6714/2099/1108/10818/10014/2248/5519/8503/5711/2261/5159/5687/2247/5685/2255/3164/5708/145957/3084/5692/54815/5686/2534/23512/9965/5728/5529/6615/2264/816/5702/7157/1107/2066/27006/5719/3654/7189/5371/9542/10542/6233/5527/2885/10718/79109/5580/2475/55004/51135/8660/2246/57504/7311/2251/3932/2931/5293/5518/5155/1386/2252/1956/5296/5581/4343/8726/8394/648/2549/115/5694/801/5781/64121/57521/5693/5691/5156/7314/5879/253260/5595/4193/5515/3556/5516 144 West_Nile_virus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 75/1715 103/10654 1.0064536421051313e-37 9.475042144961163e-36 4.169593660149829e-36 5295/3643/1839/685/5305/5290/3667/8823/5291/2065/5525/3815/5526/207/5594/2069/8074/3082/8817/2064/2260/4615/5528/2100/2254/152831/1950/2263/4233/2249/26281/6714/2099/10818/2248/5519/8503/2261/5159/2247/2255/145957/3084/2534/9965/5529/2264/2066/27006/3654/7189/9542/5527/2885/10718/51135/8660/2246/2251/3932/5293/5518/5155/2252/1956/5296/8394/2549/5781/5156/5879/5595/5515/3556/5516 75 West_Nile_virus R-HSA-5654738 Signaling by FGFR2 61/1715 73/10654 4.098526753523609e-37 3.6012388407627444e-35 1.584763678029129e-35 5295/2963/5434/5440/4893/6464/5290/23543/8823/5430/5436/5594/8074/3178/8817/10817/5441/54845/5438/5431/5435/2254/4686/7316/673/5433/3185/2263/2249/26281/6714/10818/2962/2248/5437/4670/2247/2255/5439/27006/6654/6233/2885/3187/2246/7073/7311/2251/5518/2252/3845/2549/3265/5781/5432/22916/5725/7314/5595/5515/5516 61 West_Nile_virus R-HSA-1257604 PIP3 activates AKT signaling 130/1715 264/10654 5.178458509865221e-37 4.2657551975014755e-35 1.8771912098261426e-35 5295/5718/5689/3725/3643/1839/5684/685/5305/5290/3667/8823/5682/5291/2065/5525/842/3815/2146/5526/207/6045/5690/5594/2069/5717/8074/3082/1460/8817/2064/6199/10197/2260/4615/5528/2100/2254/7316/10213/152831/1950/2263/1457/4233/1026/2249/26281/6714/2099/1108/10818/10014/2248/5519/8503/5711/2261/5159/5687/2247/5685/2255/3164/5708/145957/3084/5692/54815/5686/2534/23512/9965/5728/5529/6615/2264/5702/7157/1107/2066/27006/5719/3654/7189/5371/9542/10542/6233/5527/2885/10718/79109/2475/55004/51135/8660/2246/57504/7311/2251/3932/2931/5293/5518/5155/1386/2252/1956/5296/4343/8726/8394/648/2549/5694/5781/64121/57521/5693/5691/5156/7314/5879/253260/5595/4193/5515/3556/5516 130 West_Nile_virus R-HSA-199418 Negative regulation of the PI3K/AKT network 76/1715 110/10654 1.25567937121345e-35 9.735208301525453e-34 4.284082560610594e-34 5295/3643/1839/685/5305/5290/3667/8823/5291/2065/5525/3815/5526/207/5594/2069/8074/3082/8817/2064/2260/4615/5528/2100/2254/152831/1950/2263/4233/2249/26281/6714/2099/10818/2248/5519/8503/2261/5159/2247/2255/145957/3084/2534/9965/5728/5529/2264/2066/27006/3654/7189/9542/5527/2885/10718/51135/8660/2246/2251/3932/5293/5518/5155/2252/1956/5296/8394/2549/5781/5156/5879/5595/5515/3556/5516 76 West_Nile_virus R-HSA-449147 Signaling by Interleukins 180/1715 461/10654 4.68833049024666e-34 3.43289977008061e-32 1.5106842690794795e-32 5295/8454/6095/3605/3557/7124/5718/834/5689/3725/7291/5777/8945/596/5684/5601/3562/351/9252/1072/6464/5290/1437/3667/4790/6627/6597/5682/5291/5604/3561/11213/7412/6775/207/5292/9021/7422/29110/5690/3553/1439/5594/8878/54472/4582/5717/821/5908/3082/5743/3091/3568/3383/246330/301/9987/11009/10197/4478/1438/3576/4615/7534/3313/332/3662/5528/3688/7316/10213/9978/3560/79155/6352/3185/6774/920/5970/3936/3055/6850/1026/59307/3718/3627/177/6772/8651/4609/3146/6647/5519/5898/8503/5711/3552/3567/5687/3558/4067/3717/23291/598/2247/836/5685/5708/3320/5602/5692/5686/4843/2335/2534/3656/595/6195/3458/3181/5702/998/7157/5719/4001/3654/3563/7189/163702/5609/6654/6233/2885/7525/6844/3716/51135/8660/2353/282618/6196/7311/53832/6809/9846/3932/3575/5293/5518/6845/1386/6655/5296/3588/6197/5599/5784/375/7334/5694/3312/3559/6773/7297/5781/3569/3162/5062/4170/5693/3586/5691/3554/51231/7314/3572/5595/5515/3556/5516 180 West_Nile_virus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 45/1715 47/10654 9.547810518168179e-34 5.720006483157118e-32 2.5171500456988834e-32 818/815/4893/71/5604/283455/8844/817/3674/7094/5594/409/5908/7414/54518/673/8315/22866/6714/5605/5037/10256/3717/2244/2335/3690/408/1445/816/4296/5894/2266/8826/5906/2243/7450/60/4140/3845/3265/369/801/5245/7529/5595 45 West_Nile_virus R-HSA-6802949 Signaling by RAS mutants 45/1715 47/10654 9.547810518168179e-34 5.720006483157118e-32 2.5171500456988834e-32 818/815/4893/71/5604/283455/8844/817/3674/7094/5594/409/5908/7414/54518/673/8315/22866/6714/5605/5037/10256/3717/2244/2335/3690/408/1445/816/4296/5894/2266/8826/5906/2243/7450/60/4140/3845/3265/369/801/5245/7529/5595 45 West_Nile_virus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 45/1715 47/10654 9.547810518168179e-34 5.720006483157118e-32 2.5171500456988834e-32 818/815/4893/71/5604/283455/8844/817/3674/7094/5594/409/5908/7414/54518/673/8315/22866/6714/5605/5037/10256/3717/2244/2335/3690/408/1445/816/4296/5894/2266/8826/5906/2243/7450/60/4140/3845/3265/369/801/5245/7529/5595 45 West_Nile_virus R-HSA-9649948 Signaling downstream of RAS mutants 45/1715 47/10654 9.547810518168179e-34 5.720006483157118e-32 2.5171500456988834e-32 818/815/4893/71/5604/283455/8844/817/3674/7094/5594/409/5908/7414/54518/673/8315/22866/6714/5605/5037/10256/3717/2244/2335/3690/408/1445/816/4296/5894/2266/8826/5906/2243/7450/60/4140/3845/3265/369/801/5245/7529/5595 45 West_Nile_virus R-HSA-5663205 Infectious disease 155/1715 383/10654 2.014156831824485e-31 1.1541994366715962e-29 5.079178097644355e-30 5718/23165/5689/5905/6138/8945/1173/4928/6144/2963/3838/6917/81929/6203/5434/5440/1839/5684/8065/902/6194/6234/6191/55706/7175/79643/6128/5682/6132/9631/5604/1499/1938/3159/6147/6129/3843/2959/5430/6222/5436/6152/5690/6136/7520/8106/6125/5717/4869/821/811/6224/6146/6154/6141/9636/79023/57122/5441/10197/91782/6232/5438/6134/3981/5431/6160/5435/4686/7316/10213/1500/9978/5433/6872/2960/920/4233/3055/6714/5605/9688/8148/6205/6165/2962/6142/10898/5711/23327/5437/5687/89853/83860/999/5685/5708/3320/5692/5686/2534/6156/6235/2068/5439/6124/5702/2071/5902/6207/8086/5719/6139/5609/6233/2885/3326/6844/7514/1025/7311/6223/25873/3932/93343/3921/6188/11198/6396/6135/6201/375/6161/5694/55690/2547/801/2961/6187/5062/5432/6168/22916/5693/6208/6157/6170/5691/200916/6122/2957/7314/5879/25920/6230 155 West_Nile_virus R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 36/1715 36/10654 2.03288150268361e-29 1.1163907585570824e-27 4.912796964818725e-28 4893/71/5604/283455/8844/3674/7094/5594/409/5908/7414/54518/673/22866/6714/5605/5037/10256/2244/2335/3690/408/1445/5894/2266/8826/5906/2243/7450/60/4140/3845/3265/369/7529/5595 36 West_Nile_virus R-HSA-2219528 PI3K/AKT Signaling in Cancer 66/1715 101/10654 7.469266118919229e-29 3.937797097894217e-27 1.732869739589261e-27 5295/1839/685/5290/3667/8823/5291/2065/842/3815/207/2069/8074/3082/8817/2064/6199/2260/2100/2254/152831/1950/2263/4233/1026/2249/26281/6714/2099/10818/2248/8503/2261/5159/2247/2255/3164/145957/3084/2534/9965/5728/2264/2066/27006/9542/2885/10718/79109/2475/8660/2246/2251/3932/2931/5293/5155/2252/1956/5296/2549/5781/5156/5879/253260/4193 66 West_Nile_virus R-HSA-73856 RNA Polymerase II Transcription Termination 52/1715 67/10654 8.240391763771637e-29 4.1772447479426994e-27 1.838241239610596e-27 10921/53981/7919/6635/6432/8683/6431/6430/134353/11051/79869/51585/6428/8106/29894/6637/199746/55110/22794/81608/4686/9785/8189/11338/4116/1477/10978/65109/6429/1478/10898/9984/10250/10569/26097/10189/51362/9295/51692/23283/9939/6636/6634/10914/9775/6427/79228/6426/22916/1479/55339/6628 52 West_Nile_virus R-HSA-1226099 Signaling by FGFR in disease 50/1715 63/10654 1.4136249267257772e-28 6.900583901572498e-27 3.03667576852204e-27 5295/2963/8805/5434/5440/4893/11052/5290/8823/5430/5436/9530/8074/8817/5441/2260/5438/5431/5435/2254/4686/5433/6774/2263/2249/6772/26281/10818/2962/2248/2261/5437/2247/2255/5439/2264/27006/6654/2885/2246/2251/9846/2252/11160/3845/2549/3265/5432/22916/7750 50 West_Nile_virus R-HSA-5674135 MAP2K and MAPK activation 38/1715 40/10654 2.836816841778208e-28 1.335330213379885e-26 5.876263457969146e-27 4893/71/5604/283455/8844/3674/7094/84292/5594/409/5908/7414/54518/673/22866/6714/5605/5037/10256/2244/54756/2335/3690/408/1445/5894/2266/8826/5906/2243/7450/60/4140/3845/3265/369/7529/5595 38 West_Nile_virus R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 55/1715 75/10654 3.202058606568513e-28 1.4552804287783792e-26 6.404117213137025e-27 5295/1839/685/5290/3667/8823/5291/2065/3815/2069/8074/3082/8817/2064/2260/2100/2254/152831/1950/2263/4233/2249/26281/6714/2099/10818/2248/8503/2261/5159/2247/2255/145957/3084/2534/9965/2264/2066/27006/9542/2885/10718/8660/2246/2251/3932/5293/5155/2252/1956/5296/2549/5781/5156/5879 55 West_Nile_virus R-HSA-5655253 Signaling by FGFR2 in disease 39/1715 43/10654 5.075081561954402e-27 2.229652499551967e-25 9.811824353111843e-26 5295/2963/5434/5440/4893/5290/8823/5430/5436/8074/8817/5441/5438/5431/5435/2254/4686/5433/2263/2249/26281/10818/2962/2248/5437/2247/2255/5439/27006/6654/2885/2246/2251/2252/3845/2549/3265/5432/22916 39 West_Nile_virus R-HSA-72187 mRNA 3'-end processing 46/1715 58/10654 2.328760482642928e-26 9.90098811652703e-25 4.357035741719027e-25 10921/53981/7919/6432/8683/6431/6430/11051/79869/51585/6428/8106/29894/199746/55110/22794/81608/4686/9785/8189/11338/4116/1477/10978/65109/6429/1478/10898/9984/10250/10569/26097/10189/51362/9295/51692/23283/9939/10914/9775/6427/79228/6426/22916/1479/55339 46 West_Nile_virus R-HSA-376176 Signaling by ROBO receptors 101/1715 218/10654 3.1858927143183446e-26 1.3121895617098683e-24 5.774430544702e-25 10921/5718/5689/6138/6144/23032/6203/5684/8861/6194/2107/6234/6191/6128/5682/6132/6147/10298/6129/6222/6152/5690/6136/5578/5532/6125/5717/6224/6146/6154/6141/26986/10197/6232/2935/6134/6160/6091/55110/22794/4686/7316/10213/9978/4116/65109/6714/6205/6165/6142/5711/5687/5685/1605/5708/5692/23767/5686/5063/1981/6156/6235/9495/6124/5702/998/8453/6207/9939/5719/6139/10487/6654/6233/7311/6223/25873/387/6655/3921/6188/9775/6135/6201/6161/5694/5058/6187/5062/6168/22916/5693/6208/6157/6170/5691/200916/6122/7314/5879/6230 101 West_Nile_virus R-HSA-72165 mRNA Splicing - Minor Pathway 43/1715 52/10654 4.061745059577262e-26 1.6222363601584337e-24 7.138824650166096e-25 23451/2963/6635/5434/5440/6633/6432/6431/6632/24148/83443/5430/4904/5436/51639/11325/6637/23450/5441/5438/5431/5435/10594/4686/5433/9343/9416/57819/2962/5437/23020/5439/9410/6636/6634/6427/6426/10907/5432/22916/10992/10262/6628 43 West_Nile_virus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 86/1715 171/10654 1.3402450908440781e-25 5.1954206756838085e-24 2.286300449086957e-24 10921/5718/5689/6138/6144/23032/6203/5684/8861/6194/2107/6234/6191/6128/5682/6132/6147/6129/6222/6152/5690/6136/6125/5717/6224/6146/6154/6141/26986/10197/6232/2935/6134/6160/6091/55110/22794/4686/7316/10213/9978/4116/65109/6205/6165/6142/5711/5687/5685/1605/5708/5692/5686/1981/6156/6235/6124/5702/8453/6207/9939/5719/6139/6233/7311/6223/25873/3921/6188/9775/6135/6201/6161/5694/6187/6168/22916/5693/6208/6157/6170/5691/200916/6122/7314/6230 86 West_Nile_virus R-HSA-168254 Influenza Infection 80/1715 155/10654 7.5147368460037395e-025 2.8298351894379797e-23 1.245299248766334e-23 23165/6138/4928/6144/2963/3838/81929/6203/5434/5440/6194/6234/6191/55706/7175/6128/6132/9631/6147/6129/3843/5430/6222/5436/6152/6136/8106/6125/821/811/6224/6146/6154/6141/9636/79023/57122/5441/6232/5438/6134/5431/6160/5435/5433/9688/6205/6165/2962/6142/10898/5437/3320/6156/6235/5439/6124/6207/8086/6139/6233/7514/7311/6223/25873/3921/6188/6396/6135/6201/6161/6187/5432/6168/6208/6157/6170/200916/6122/6230 80 West_Nile_virus R-HSA-168273 Influenza Viral RNA Transcription and Replication 73/1715 134/10654 1.1451797954150405e-24 4.192630473213954e-23 1.8450118926131208e-23 23165/6138/4928/6144/2963/81929/6203/5434/5440/6194/6234/6191/55706/7175/6128/6132/9631/6147/6129/3843/5430/6222/5436/6152/6136/6125/6224/6146/6154/6141/79023/57122/5441/6232/5438/6134/5431/6160/5435/5433/9688/6205/6165/2962/6142/5437/3320/6156/6235/5439/6124/6207/8086/6139/6233/7311/6223/25873/3921/6188/6396/6135/6201/6161/6187/5432/6168/6208/6157/6170/200916/6122/6230 73 West_Nile_virus R-HSA-168255 Influenza Life Cycle 76/1715 144/10654 1.8168602780829337e-24 6.47195093652245e-23 2.848051246724599e-23 23165/6138/4928/6144/2963/81929/6203/5434/5440/6194/6234/6191/55706/7175/6128/6132/9631/6147/6129/3843/5430/6222/5436/6152/6136/6125/821/811/6224/6146/6154/6141/79023/57122/5441/6232/5438/6134/5431/6160/5435/5433/9688/6205/6165/2962/6142/5437/3320/6156/6235/5439/6124/6207/8086/6139/6233/7514/7311/6223/25873/3921/6188/6396/6135/6201/6161/6187/5432/6168/6208/6157/6170/200916/6122/6230 76 West_Nile_virus R-HSA-5654736 Signaling by FGFR1 40/1715 50/10654 2.4460964143975545e-23 8.484092300463096e-22 3.733515579869951e-22 5295/4893/6464/5290/23768/5594/8074/8817/10817/2260/2254/7316/673/2249/26281/6714/10818/2248/2247/2255/23767/27006/6654/6233/2885/2246/7311/2251/5518/53834/3845/2549/3265/200734/5781/7314/161742/5595/5515/5516 40 West_Nile_virus R-HSA-5654743 Signaling by FGFR4 35/1715 41/10654 2.1213421605328643e-22 7.169048634826449e-21 3.1548165464334905e-21 5295/4893/6464/5290/8823/5594/8074/8817/10817/2254/7316/673/152831/2249/26281/6714/10818/2247/9965/2264/6654/6233/2885/2246/7311/2251/5518/3845/2549/3265/5781/7314/5595/5515/5516 35 West_Nile_virus R-HSA-74751 Insulin receptor signalling cascade 41/1715 54/10654 2.5214503720814383e-22 8.30817897600834e-21 3.6561030395180856e-21 5295/54106/3643/4893/6464/5290/3667/8823/5291/5594/2322/8074/8817/2260/2254/152831/2263/2249/26281/10818/2248/2261/2247/2255/9965/2264/27006/6654/2885/8660/2246/2251/9846/2252/5296/3845/2549/3265/5781/2323/5595 41 West_Nile_virus R-HSA-5673000 RAF activation 30/1715 32/10654 4.573564432970151e-22 1.470233639671868e-20 6.4699204173724085e-21 818/815/4893/5604/5525/5526/8844/817/5528/673/8315/6714/5605/5519/3717/5529/816/4296/5894/5527/5518/4140/3845/3265/369/801/5245/7529/5515/5516 30 West_Nile_virus R-HSA-2428924 IGF1R signaling cascade 40/1715 53/10654 1.2134801966340836e-21 3.8080164265802905e-20 1.6757583667804013e-20 5295/54106/4893/6464/5290/3667/8823/5291/2322/8074/8817/2260/2254/152831/2263/2249/26281/10818/2248/2261/2247/2255/9965/8471/2264/27006/6654/2885/8660/2246/2251/9846/2252/5296/3845/2549/3265/5781/3480/2323 40 West_Nile_virus R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 40/1715 54/10654 3.9601520807081285e-21 1.2138326610170497e-19 5.3416004809551507e-20 5295/54106/4893/6464/5290/3667/8823/5291/2322/8074/8817/2260/2254/152831/2263/2249/26281/10818/2248/2261/2247/2255/9965/8471/2264/27006/6654/2885/8660/2246/2251/9846/2252/5296/3845/2549/3265/5781/3480/2323 40 West_Nile_virus R-HSA-1839126 FGFR2 mutant receptor activation 30/1715 33/10654 4.258893582116204e-21 1.2757322139157174e-19 5.613996085516816e-20 2963/5434/5440/8823/5430/5436/8074/8817/5441/5438/5431/5435/2254/4686/5433/2263/2249/26281/2962/2248/5437/2247/2255/5439/27006/2246/2251/2252/5432/22916 30 West_Nile_virus R-HSA-2428928 IRS-related events triggered by IGF1R 39/1715 52/10654 5.802625072157196e-21 1.6995244100229296e-19 7.478938981891496e-20 5295/54106/4893/5290/3667/8823/5291/2322/8074/8817/2260/2254/152831/2263/2249/26281/10818/2248/2261/2247/2255/9965/8471/2264/27006/6654/2885/8660/2246/2251/9846/2252/5296/3845/2549/3265/5781/3480/2323 39 West_Nile_virus R-HSA-927802 Nonsense-Mediated Decay (NMD) 62/1715 115/10654 8.050746508719989e-21 2.2576348720197754e-19 9.934963776718283e-20 10921/6138/6144/6203/6194/2107/6234/6191/6128/6132/6147/6129/6222/6152/6136/6125/6224/6146/6154/6141/26986/6232/2935/6134/6160/55110/22794/4686/4116/65109/6205/6165/6142/1981/6156/6235/6124/6207/9939/6139/6233/7311/6223/25873/5518/3921/6188/23293/9775/6135/6201/6161/6187/6168/22916/6208/6157/6170/200916/6122/5515/6230 62 West_Nile_virus R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 62/1715 115/10654 8.050746508719989e-21 2.2576348720197754e-19 9.934963776718283e-20 10921/6138/6144/6203/6194/2107/6234/6191/6128/6132/6147/6129/6222/6152/6136/6125/6224/6146/6154/6141/26986/6232/2935/6134/6160/55110/22794/4686/4116/65109/6205/6165/6142/1981/6156/6235/6124/6207/9939/6139/6233/7311/6223/25873/5518/3921/6188/23293/9775/6135/6201/6161/6187/6168/22916/6208/6157/6170/200916/6122/5515/6230 62 West_Nile_virus R-HSA-112399 IRS-mediated signalling 37/1715 48/10654 1.1561176671573523e-20 3.1745064277362296e-19 1.3969755144818005e-19 5295/54106/4893/5290/3667/8823/5291/2322/8074/8817/2260/2254/152831/2263/2249/26281/10818/2248/2261/2247/2255/9965/2264/27006/6654/2885/8660/2246/2251/9846/2252/5296/3845/2549/3265/5781/2323 37 West_Nile_virus R-HSA-72613 Eukaryotic Translation Initiation 63/1715 119/10654 1.3871029303362264e-20 3.656403324366293e-19 1.6090393991900227e-19 6138/6144/6203/8891/6194/1965/6234/6191/6128/6132/6147/8666/6129/6222/1983/6152/6136/8668/6125/6224/6146/6154/6141/26986/6232/6134/6160/8661/9669/6205/6165/6142/8663/8894/1981/6156/6235/1973/6124/6207/1977/6139/6233/7311/6223/25873/8664/3646/3921/6188/6135/6201/6161/6187/6168/6208/6157/6170/8892/200916/6122/1968/6230 63 West_Nile_virus R-HSA-72737 Cap-dependent Translation Initiation 63/1715 119/10654 1.3871029303362264e-20 3.656403324366293e-19 1.6090393991900227e-19 6138/6144/6203/8891/6194/1965/6234/6191/6128/6132/6147/8666/6129/6222/1983/6152/6136/8668/6125/6224/6146/6154/6141/26986/6232/6134/6160/8661/9669/6205/6165/6142/8663/8894/1981/6156/6235/1973/6124/6207/1977/6139/6233/7311/6223/25873/8664/3646/3921/6188/6135/6201/6161/6187/6168/6208/6157/6170/8892/200916/6122/1968/6230 63 West_Nile_virus R-HSA-166520 Signaling by NTRKs 57/1715 101/10654 1.5506319173418857e-20 4.007319347169814e-19 1.7634637491339095e-19 5295/4908/627/1173/9252/4893/6464/5290/3667/5899/4915/5291/5604/2904/5594/7074/1785/10817/5528/673/6774/57498/6714/5605/10818/26052/5519/5898/4909/4914/53358/2534/6195/5603/6654/2885/5900/8660/6196/5906/5518/387/5296/6197/3845/2549/3265/5781/51231/4916/7529/5879/5595/25759/5515/25920/5516 57 West_Nile_virus R-HSA-913531 Interferon Signaling 86/1715 199/10654 5.0878167717405235e-20 1.2895658663757712e-18 5.674872553095199e-19 3443/23165/3665/818/3460/5777/4928/815/3838/81929/3441/10379/55706/7175/960/5770/9631/3455/4281/7412/3107/817/9021/9636/2209/79023/3383/57122/3449/1982/7706/3444/3662/4684/7316/3663/3664/103/3434/6772/8651/9688/3433/3659/23586/8672/3459/6059/3451/3717/3448/1981/3440/1973/10612/3458/3454/816/3661/8086/9246/1977/5371/4599/6233/5580/3716/7311/5300/9775/3452/4940/6396/3437/7334/3456/6773/4938/7297/5781/3105/3660/3446/7314/3445/5595 86 West_Nile_virus R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 60/1715 112/10654 5.258257065276852e-20 1.3076193984971493e-18 5.75431905256712e-19 6138/6144/6203/6194/1965/6234/6191/6128/6132/6147/8666/6129/6222/1983/6152/6136/8668/6125/6224/6146/6154/6141/6232/6134/6160/8661/9669/6205/6165/6142/8663/8894/1981/6156/6235/1973/6124/6207/1977/6139/6233/7311/6223/25873/8664/3646/3921/6188/6135/6201/6161/6187/6168/6208/6157/6170/200916/6122/1968/6230 60 West_Nile_virus R-HSA-1227986 Signaling by ERBB2 37/1715 50/10654 1.3000877272397023e-19 3.173177082410977e-18 1.3963905218500505e-18 5295/1839/4893/8065/6464/685/5290/2065/207/5578/2069/2064/7316/1950/51072/6714/145957/3320/3084/2534/2066/6654/9542/6233/2885/7525/10718/5580/7311/387/1956/5581/3845/2549/3265/11140/7314 37 West_Nile_virus R-HSA-72202 Transport of Mature Transcript to Cytoplasm 50/1715 84/10654 1.4874579282426583e-19 3.564490089861498e-18 1.568591997055894e-18 10921/23165/53981/7919/4928/81929/6432/8683/6431/6430/55706/7175/9631/6428/29894/199746/79023/57122/55110/22794/81608/4686/9785/8189/11338/4116/65109/6429/9688/10898/9984/10250/10569/26097/10189/51362/9295/10482/51692/8086/9939/1977/9775/6396/6427/79228/2733/6426/22916/55339 50 West_Nile_virus R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 59/1715 111/10654 1.7991654997348864e-19 4.234464515447465e-18 1.863421410439704e-18 6138/6144/6203/6194/1965/6234/6191/6128/6132/6147/8666/6129/6222/6152/6136/8668/6125/6224/6146/6154/6141/26986/6232/6134/6160/8661/6205/6165/6142/8663/8894/1981/6156/6235/1973/6124/6207/1977/6139/6233/7311/6223/25873/8664/3646/3921/6188/6135/6201/6161/6187/6168/6208/6157/6170/200916/6122/1968/6230 59 West_Nile_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 36/1715 48/10654 1.9086761650364827e-19 4.413395062312428e-18 1.9421617117915087e-18 5295/5777/3562/6464/5290/1437/5291/3561/1439/3568/1438/7534/7316/3560/3055/6850/3718/8503/3567/3558/4067/3717/2534/3563/6654/6233/2885/7525/3716/7311/9846/5293/5296/3559/5781/7314 36 West_Nile_virus R-HSA-5654741 Signaling by FGFR3 32/1715 40/10654 6.553304690093423e-19 1.4891819968177812e-17 6.553304690093423e-18 5295/4893/6464/5290/8823/5594/8074/8817/10817/2254/7316/673/2249/26281/6714/10818/2261/2247/6654/6233/2885/2246/7311/5518/3845/2549/3265/5781/7314/5595/5515/5516 32 West_Nile_virus R-HSA-74752 Signaling by Insulin receptor 47/1715 78/10654 9.12198031500599e-19 2.0377576364708295e-17 8.967370479158432e-18 5295/54106/3643/4893/6464/5290/3667/8823/5291/9550/9114/5594/2322/8074/8817/2260/2254/152831/527/2263/2249/26281/10818/2248/2261/2247/245972/2255/9965/2264/533/27006/6654/2885/8660/2246/2251/9846/2252/5296/3845/2549/3265/5781/2323/51382/5595 47 West_Nile_virus R-HSA-912526 Interleukin receptor SHC signaling 25/1715 27/10654 3.205510260098283e-18 7.041437538015894e-17 3.098659918095007e-17 5295/5777/3562/6464/5290/1437/5291/3561/1439/3568/1438/3560/3718/8503/3567/3558/3717/3563/6654/2885/3716/9846/5293/5296/3559 25 West_Nile_virus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 52/1715 95/10654 4.677584303225476e-18 1.0106649363362587e-16 4.4475391735586493e-17 6138/6144/6203/6194/2107/6234/6191/6128/6132/6147/6129/6222/6152/6136/6125/6224/6146/6154/6141/26986/6232/2935/6134/6160/4686/6205/6165/6142/1981/6156/6235/6124/6207/6139/6233/7311/6223/25873/3921/6188/6135/6201/6161/6187/6168/22916/6208/6157/6170/200916/6122/6230 52 West_Nile_virus R-HSA-109704 PI3K Cascade 33/1715 44/10654 6.27442525148547e-18 1.3338213679770723e-16 5.869623622357375e-17 5295/54106/5290/3667/8823/5291/2322/8074/8817/2260/2254/152831/2263/2249/26281/10818/2248/2261/2247/2255/9965/2264/27006/2885/8660/2246/2251/9846/2252/5296/2549/5781/2323 33 West_Nile_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 64/1715 134/10654 6.928792512331723e-18 1.449547385913208e-16 6.378888344686348e-17 5295/8454/5718/5689/3725/8945/9402/5684/5601/4893/6464/5290/4790/5682/5291/7321/5690/5532/5594/5717/10197/7316/10213/10125/5970/6850/10768/5711/5687/4067/23291/5685/5708/5602/5692/5686/2534/5702/695/5719/7189/5609/6654/6233/2885/10235/2353/7311/9846/115727/5296/3845/5599/7334/5694/3265/5058/801/5062/5693/5691/7314/5879/5595 64 West_Nile_virus R-HSA-6803529 FGFR2 alternative splicing 24/1715 26/10654 1.8665415821317548e-17 3.8439090707025826e-16 1.6915533088069028e-16 2963/5434/5440/23543/5430/5436/3178/5441/54845/5438/5431/5435/4686/5433/3185/2962/5437/4670/5439/3187/7073/5432/22916/5725 24 West_Nile_virus R-HSA-5654727 Negative regulation of FGFR2 signaling 28/1715 34/10654 2.532120708263016e-17 5.061469000290869e-16 2.227353581311612e-16 8823/5594/8074/8817/2254/7316/673/2263/2249/26281/6714/10818/2248/2247/2255/27006/6233/2885/2246/7311/2251/5518/2252/5781/7314/5595/5515/5516 28 West_Nile_virus R-HSA-75067 Processing of Capped Intronless Pre-mRNA 25/1715 28/10654 2.5345747649407997e-17 5.061469000290869e-16 2.227353581311612e-16 53981/6635/134353/11051/79869/51585/8106/29894/6637/81608/4686/8189/1477/10978/1478/10898/51692/23283/6636/6634/10914/22916/1479/55339/6628 25 West_Nile_virus R-HSA-5654696 Downstream signaling of activated FGFR2 26/1715 30/10654 2.8539974108702864e-17 5.614281473920952e-16 2.4706246243354716e-16 5295/4893/6464/5290/8823/8074/8817/10817/2254/2263/2249/26281/10818/2248/2247/2255/27006/6654/2885/2246/2251/2252/3845/2549/3265/5781 26 West_Nile_virus R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 56/1715 112/10654 5.937220777487576e-17 1.1507730859895037e-15 5.064100074915873e-16 6138/6144/6203/6194/6234/6191/6128/10952/6132/6147/6129/6222/6152/6136/6125/6727/6224/6146/6154/6141/6232/58477/6134/6160/29927/6729/6205/6165/6142/28972/6156/6235/6124/6207/6139/6745/6726/6233/7311/6223/25873/6730/3921/6188/9789/6135/6201/6161/6187/6168/6208/6157/6170/200916/6122/6230 56 West_Nile_virus R-HSA-5654716 Downstream signaling of activated FGFR4 24/1715 27/10654 1.4234466031107055e-16 2.718989308550594e-15 1.1965203330495786e-15 5295/4893/6464/5290/8823/8074/8817/10817/2254/152831/2249/26281/10818/2247/9965/2264/6654/2885/2246/2251/3845/2549/3265/5781 24 West_Nile_virus R-HSA-5658442 Regulation of RAS by GAPs 41/1715 68/10654 1.4924375879177334e-16 2.7823991381372483e-15 1.2244245069192748e-15 5718/22821/5689/10156/9462/5684/4893/5682/8831/153090/5690/5717/5921/10197/8452/7316/10213/9978/64926/5711/8437/5687/5922/5685/5708/5692/5686/5702/5719/6233/7311/399473/3845/5694/3265/200734/4763/5693/5691/7314/161742 41 West_Nile_virus R-HSA-5654733 Negative regulation of FGFR4 signaling 26/1715 31/10654 1.4988644826080776e-16 2.7823991381372483e-15 1.2244245069192748e-15 8823/5594/8074/8817/2254/7316/673/152831/2249/26281/6714/10818/2247/9965/2264/6233/2885/2246/7311/2251/5518/5781/7314/5595/5515/5516 26 West_Nile_virus R-HSA-72689 Formation of a pool of free 40S subunits 52/1715 101/10654 1.5541083652566e-16 2.8448817019558318e-15 1.2519206275678165e-15 6138/6144/6203/6194/6234/6191/6128/6132/6147/8666/6129/6222/6152/6136/8668/6125/6224/6146/6154/6141/6232/6134/6160/8661/6205/6165/6142/8663/6156/6235/6124/6207/6139/6233/7311/6223/25873/8664/3646/3921/6188/6135/6201/6161/6187/6168/6208/6157/6170/200916/6122/6230 52 West_Nile_virus R-HSA-162906 HIV Infection 89/1715 233/10654 1.576010075541071e-16 2.8454538076207283e-15 1.2521723887860564e-15 5718/23165/5689/5905/8945/1173/4928/2963/6917/81929/5434/5440/5684/8065/902/55706/7175/79643/5682/9631/3159/2959/5430/5436/5690/7520/5717/4869/79023/57122/5441/10197/91782/5438/3981/5431/5435/4686/7316/10213/9978/5433/6872/2960/920/3055/9688/8148/2962/5711/23327/5437/5687/89853/83860/5685/5708/5692/5686/2534/2068/5439/5702/2071/5902/8086/5719/6233/7514/1025/7311/3932/93343/11198/6396/375/5694/55690/2547/2961/5062/5432/22916/5693/5691/2957/7314/5879/25920 89 West_Nile_virus R-HSA-156902 Peptide chain elongation 48/1715 89/10654 2.0113665096613482e-16 3.582406837477915e-15 1.5764764535183541e-15 6138/6144/6203/6194/6234/6191/6128/6132/1938/6147/6129/1915/6222/6152/6136/6125/6224/6146/6154/6141/6232/6134/6160/6205/6165/6142/6156/6235/6124/6207/6139/6233/7311/6223/25873/3921/6188/6135/6201/6161/6187/6168/6208/6157/6170/200916/6122/6230 48 West_Nile_virus R-HSA-187037 Signaling by NTRK1 (TRKA) 45/1715 80/10654 2.0522720270330703e-16 3.606526042172782e-15 1.5870903675722412e-15 5295/1173/9252/4893/6464/5290/3667/5899/4915/5291/5604/5594/1785/5528/673/6774/57498/6714/5605/10818/26052/5519/5898/4914/53358/6195/5603/6654/2885/5900/8660/6196/5906/5518/387/5296/6197/3845/3265/51231/7529/5595/25759/5515/5516 45 West_Nile_virus R-HSA-909733 Interferon alpha/beta signaling 41/1715 69/10654 3.1118726747396604e-16 5.39664234908799e-15 2.374850199143425e-15 3443/3665/5777/3441/10379/5770/3455/3107/9021/9636/3449/3444/3662/3663/3664/103/3434/6772/8651/3433/3659/6059/3451/3448/3440/3454/3661/4599/3716/3452/4940/3437/3456/6773/4938/7297/5781/3105/3660/3446/3445 41 West_Nile_virus R-HSA-1250196 SHC1 events in ERBB2 signaling 21/1715 22/10654 3.696022399637563e-16 6.326438341197802e-15 2.784016872454268e-15 1839/4893/6464/685/2065/5578/2069/2064/1950/145957/3084/2066/6654/9542/2885/10718/5580/1956/5581/3845/3265 21 West_Nile_virus R-HSA-77595 Processing of Intronless Pre-mRNAs 19/1715 19/10654 7.794574715347286e-16 1.30041132592756e-14 5.722599158103071e-15 53981/11051/79869/51585/8106/29894/81608/4686/8189/1477/10978/1478/10898/51692/23283/10914/22916/1479/55339 19 West_Nile_virus R-HSA-8851708 Signaling by FGFR2 IIIa TM 19/1715 19/10654 7.794574715347286e-16 1.30041132592756e-14 5.722599158103071e-15 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2263/2962/5437/2247/5439/2246/5432/22916 19 West_Nile_virus R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 25/1715 30/10654 7.913713003761448e-16 1.3037842173696986e-14 5.73744192772705e-15 5923/818/815/4893/2904/817/5594/2902/27330/6195/816/1741/2906/1742/1739/88/6196/1740/6197/3845/3265/801/5924/4747/5595 25 West_Nile_virus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 35/1715 54/10654 9.89734363900343e-16 1.571650471832111e-14 6.9162160368939644e-15 10450/9318/6917/5434/5440/902/27339/5430/5436/5441/5438/5431/8450/5435/7316/9978/5433/64708/10980/5437/10920/2033/2068/5439/10987/2071/6233/7311/56949/9716/57461/5432/7314/51138/8451 35 West_Nile_virus R-HSA-8848021 Signaling by PTK6 35/1715 54/10654 9.89734363900343e-16 1.571650471832111e-14 6.9162160368939644e-15 1017/1839/1019/4893/685/5770/2065/207/2909/9021/2069/202559/3091/2064/5921/10657/7316/1950/6774/6421/2908/145957/3084/595/2066/9542/6233/10718/7311/387/1956/3845/3265/7314/5879 35 West_Nile_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 35/1715 54/10654 9.89734363900343e-16 1.571650471832111e-14 6.9162160368939644e-15 1017/1839/1019/4893/685/5770/2065/207/2909/9021/2069/202559/3091/2064/5921/10657/7316/1950/6774/6421/2908/145957/3084/595/2066/9542/6233/10718/7311/387/1956/3845/3265/7314/5879 35 West_Nile_virus R-HSA-451927 Interleukin-2 family signaling 31/1715 44/10654 1.2144148716711571e-15 1.9054747629316487e-14 8.385245542491324e-15 5295/5777/3562/6464/5290/1437/5291/3561/6775/1439/3568/1438/3560/6774/6850/3718/6772/8503/3567/3558/3717/3563/6654/2885/3716/9846/3932/5293/6655/5296/3559 31 West_Nile_virus R-HSA-156842 Eukaryotic Translation Elongation 48/1715 93/10654 2.0191754290540397e-15 3.09450373894561e-14 1.3617694754085386e-14 6138/6144/6203/6194/6234/6191/6128/6132/1938/6147/6129/1915/6222/6152/6136/6125/6224/6146/6154/6141/6232/6134/6160/6205/6165/6142/6156/6235/6124/6207/6139/6233/7311/6223/25873/3921/6188/6135/6201/6161/6187/6168/6208/6157/6170/200916/6122/6230 48 West_Nile_virus R-HSA-72764 Eukaryotic Translation Termination 48/1715 93/10654 2.0191754290540397e-15 3.09450373894561e-14 1.3617694754085386e-14 6138/6144/6203/6194/2107/6234/6191/6128/6132/6147/6129/6222/6152/6136/6125/6224/6146/6154/6141/6232/2935/6134/6160/6205/6165/6142/6156/6235/6124/6207/6139/6233/7311/6223/25873/3921/6188/6135/6201/6161/6187/6168/6208/6157/6170/200916/6122/6230 48 West_Nile_virus R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 42/1715 75/10654 2.5779607146366464e-15 3.905462324012759e-14 1.7186404764244312e-14 10921/23165/7919/4928/81929/6432/8683/6431/6430/55706/7175/9631/6428/199746/79023/57122/55110/22794/4686/9785/11338/4116/65109/6429/9688/9984/10250/10569/26097/10189/51362/9295/10482/8086/9939/9775/6396/6427/79228/2733/6426/22916 42 West_Nile_virus R-HSA-5675221 Negative regulation of MAPK pathway 29/1715 40/10654 3.005604509252999e-15 4.501575844540287e-14 1.9809666083712947e-14 4893/5604/5525/5526/8844/5594/5528/7316/673/8315/5605/5037/5519/5529/5894/6233/5527/7311/5518/5536/4140/3845/3265/369/7529/7314/5595/5515/5516 29 West_Nile_virus R-HSA-5654687 Downstream signaling of activated FGFR1 25/1715 31/10654 3.4642248508566675e-15 5.1301666892461664e-14 2.257584734266143e-14 5295/4893/6464/5290/23768/8074/10817/2260/2254/2249/26281/10818/2248/2247/2255/23767/27006/6654/2885/2246/2251/3845/2549/3265/5781 25 West_Nile_virus R-HSA-5654700 FRS-mediated FGFR2 signaling 22/1715 25/10654 4.422878446265147e-15 6.47705976908607e-14 2.850299443148651e-14 4893/8823/8074/8817/10817/2254/2263/2249/26281/10818/2248/2247/2255/27006/6654/2885/2246/2251/2252/3845/3265/5781 22 West_Nile_virus R-HSA-192823 Viral mRNA Translation 46/1715 89/10654 7.270782808767758e-15 1.053065026588561e-13 4.6341253066871426e-14 6138/6144/6203/6194/6234/6191/6128/6132/6147/6129/6222/6152/6136/6125/6224/6146/6154/6141/6232/6134/6160/6205/6165/6142/6156/6235/6124/6207/6139/6233/7311/6223/25873/3921/6188/6135/6201/6161/6187/6168/6208/6157/6170/200916/6122/6230 46 West_Nile_virus R-HSA-2408557 Selenocysteine synthesis 47/1715 93/10654 1.1336801714566035e-14 1.6241200717171774e-13 7.147114124400326e-14 6138/6144/6203/6194/6234/6191/6128/6132/6147/6129/6222/6152/6136/6125/6224/6146/6154/6141/6232/6134/60678/6160/6205/6165/6142/6156/6235/6124/6207/6139/6233/7311/6223/25873/3921/6188/6135/6201/6161/6187/6168/6208/6157/6170/200916/6122/6230 47 West_Nile_virus R-HSA-5654712 FRS-mediated FGFR4 signaling 20/1715 22/10654 2.0659019593544613e-14 2.9278051423969677e-13 1.2884119746511695e-13 4893/8823/8074/8817/10817/2254/152831/2249/26281/10818/2247/9965/2264/6654/2885/2246/2251/3845/3265/5781 20 West_Nile_virus R-HSA-912694 Regulation of IFNA signaling 22/1715 26/10654 2.437326846039416e-14 3.417443386255266e-13 1.5038825220243205e-13 3443/5777/3441/5770/3455/9021/3449/3444/6772/8651/3451/3448/3440/3454/3716/3452/3456/6773/7297/5781/3446/3445 22 West_Nile_virus R-HSA-2408522 Selenoamino acid metabolism 54/1715 118/10654 2.5929258568759443e-14 3.5973434519605207e-13 1.5830494705137344e-13 6138/6144/6203/6194/6234/6191/6128/6132/6147/9521/6129/4143/9255/6222/6152/6136/6125/11185/6224/6146/6154/6141/6232/6134/60678/6160/6205/6165/6142/9061/7965/6156/6235/6124/6207/6139/6233/7311/6223/25873/3921/6188/6135/6201/6161/6187/9060/6168/6208/6157/6170/200916/6122/6230 54 West_Nile_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 47/1715 95/10654 3.212091147031691e-14 4.3644702389564625e-13 1.9206318198746194e-13 8454/3725/8945/5601/351/9252/4790/5604/11213/5594/246330/7099/4615/5528/7316/79155/5970/59307/177/8651/3146/5519/23291/929/5602/3656/6195/695/3654/7189/5609/6233/51135/2353/6196/7311/5518/1386/6197/5599/7334/7097/51231/7314/5595/5515/5516 47 West_Nile_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 47/1715 95/10654 3.212091147031691e-14 4.3644702389564625e-13 1.9206318198746194e-13 8454/3725/8945/5601/351/9252/4790/5604/11213/5594/246330/7099/4615/5528/7316/79155/5970/59307/177/8651/3146/5519/23291/929/5602/3656/6195/695/3654/7189/5609/6233/51135/2353/6196/7311/5518/1386/6197/5599/7334/7097/51231/7314/5595/5515/5516 47 West_Nile_virus R-HSA-4420097 VEGFA-VEGFR2 Pathway 48/1715 99/10654 4.6068120906387054e-14 6.195692179042667e-13 2.726480625071887e-13 5295/5590/4893/5290/71/5579/5291/1495/1499/6461/5747/207/7422/10458/5578/3315/5921/1500/10768/6714/1003/10163/3320/55845/5063/2534/9475/3690/3728/5603/998/79109/5580/2475/23191/6093/387/60/5296/3845/3265/5058/801/8877/5062/5879/253260/25759 48 West_Nile_virus R-HSA-5654726 Negative regulation of FGFR1 signaling 25/1715 33/10654 4.6898483328787345e-14 6.243656669428456e-13 2.7475879121915816e-13 5594/8074/2260/2254/7316/673/2249/26281/6714/10818/2248/2247/2255/27006/6233/2885/2246/7311/2251/5518/5781/7314/5595/5515/5516 25 West_Nile_virus R-HSA-9020702 Interleukin-1 signaling 49/1715 103/10654 6.379774457388546e-14 8.408542734838103e-13 3.700269185285357e-13 8454/3557/5718/5689/8945/5684/351/4790/5682/5604/11213/5690/3553/8878/54472/5717/246330/10197/4615/7316/10213/9978/79155/5970/177/3146/5711/3552/5687/23291/5685/5708/5692/5686/3656/5702/5719/3654/7189/6233/51135/7311/7334/5694/5693/5691/3554/7314/3556 49 West_Nile_virus R-HSA-5654732 Negative regulation of FGFR3 signaling 23/1715 29/10654 8.851021779744319e-14 1.15501452531713e-12 5.082764982427431e-13 8823/5594/8074/8817/2254/7316/673/2249/26281/6714/10818/2261/2247/6233/2885/2246/7311/5518/5781/7314/5595/5515/5516 23 West_Nile_virus R-HSA-354192 Integrin alphaIIb beta3 signaling 22/1715 27/10654 1.1158958581421929e-13 1.4279133408071943e-12 6.283685414781281e-13 6464/5770/5747/207/3674/7094/5908/54518/10125/6850/6714/2244/2335/3690/1445/6654/2885/2266/10235/5906/2243/7450 22 West_Nile_virus R-HSA-9006921 Integrin signaling 22/1715 27/10654 1.1158958581421929e-13 1.4279133408071943e-12 6.283685414781281e-13 6464/5770/5747/207/3674/7094/5908/54518/10125/6850/6714/2244/2335/3690/1445/6654/2885/2266/10235/5906/2243/7450 22 West_Nile_virus R-HSA-5654708 Downstream signaling of activated FGFR3 21/1715 25/10654 1.296015652586477e-13 1.6268082191514061e-12 7.158943604763397e-13 5295/4893/6464/5290/8823/8074/8817/10817/2254/2249/26281/10818/2261/2247/6654/2885/2246/3845/2549/3265/5781 21 West_Nile_virus R-HSA-9006115 Signaling by NTRK2 (TRKB) 21/1715 25/10654 1.296015652586477e-13 1.6268082191514061e-12 7.158943604763397e-13 5295/4908/627/4893/6464/5290/4915/2904/7074/10817/6714/10818/4909/2534/6654/2885/3845/2549/3265/5781/5879 21 West_Nile_virus R-HSA-5654695 PI-3K cascade:FGFR2 20/1715 23/10654 1.3435761684019154e-13 1.6549844765922658e-12 7.282936239935616e-13 5295/5290/8823/8074/8817/2254/2263/2249/26281/10818/2248/2247/2255/27006/2885/2246/2251/2252/2549/5781 20 West_Nile_virus R-HSA-5654699 SHC-mediated cascade:FGFR2 20/1715 23/10654 1.3435761684019154e-13 1.6549844765922658e-12 7.282936239935616e-13 4893/6464/8823/8074/8817/2254/2263/2249/26281/2248/2247/2255/27006/6654/2885/2246/2251/2252/3845/3265 20 West_Nile_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 47/1715 98/10654 1.4207319607001003e-13 1.717912591011681e-12 7.55985813950512e-13 8454/3725/8945/5601/351/9252/4790/5604/11213/5594/246330/7099/4615/5528/7316/79155/5970/59307/177/8651/3146/5519/23291/929/5602/3656/6195/695/3654/7189/5609/6233/51135/2353/6196/7311/5518/1386/6197/5599/7334/7097/51231/7314/5595/5515/5516 47 West_Nile_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 47/1715 98/10654 1.4207319607001003e-13 1.717912591011681e-12 7.55985813950512e-13 8454/3725/8945/5601/351/9252/4790/5604/11213/5594/246330/7099/4615/5528/7316/79155/5970/59307/177/8651/3146/5519/23291/929/5602/3656/6195/695/3654/7189/5609/6233/51135/2353/6196/7311/5518/1386/6197/5599/7334/7097/51231/7314/5595/5515/5516 47 West_Nile_virus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 41/1715 79/10654 1.7844581546227283e-13 2.1381053161752327e-12 9.40896117891984e-13 10450/9318/6118/6917/5434/5440/902/27339/5430/5436/5441/5438/5431/8450/5435/7316/9978/5433/64708/5426/10980/6119/5437/5427/5985/10920/2033/2068/5439/10987/2071/6233/7311/56949/9716/6117/57461/5432/7314/51138/8451 41 West_Nile_virus R-HSA-1963640 GRB2 events in ERBB2 signaling 16/1715 16/10654 1.9161830365257124e-13 2.2549368233400794e-12 9.923090724865296e-13 1839/4893/685/2069/2064/1950/145957/3084/2066/6654/9542/2885/10718/1956/3845/3265 16 West_Nile_virus R-HSA-1963642 PI3K events in ERBB2 signaling 16/1715 16/10654 1.9161830365257124e-13 2.2549368233400794e-12 9.923090724865296e-13 5295/1839/685/5290/2065/2069/2064/1950/145957/3084/2066/9542/2885/10718/1956/2549 16 West_Nile_virus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 43/1715 86/10654 2.493008501790183e-13 2.8822677239995274e-12 1.26837274652483e-12 8454/5718/1017/5689/8945/26271/5684/5682/7321/8697/5690/9212/5717/10197/8881/7316/10213/890/983/6790/5711/5687/5685/5708/5692/5686/5702/51529/5719/64682/29945/10393/4751/6233/7311/9184/5347/29882/5694/5693/5691/7314/996 43 West_Nile_virus R-HSA-453276 Regulation of mitotic cell cycle 43/1715 86/10654 2.493008501790183e-13 2.8822677239995274e-12 1.26837274652483e-12 8454/5718/1017/5689/8945/26271/5684/5682/7321/8697/5690/9212/5717/10197/8881/7316/10213/890/983/6790/5711/5687/5685/5708/5692/5686/5702/51529/5719/64682/29945/10393/4751/6233/7311/9184/5347/29882/5694/5693/5691/7314/996 43 West_Nile_virus R-HSA-8878159 Transcriptional regulation by RUNX3 46/1715 96/10654 2.6925189220478943e-13 3.085860816747065e-12 1.3579660650328511e-12 57154/5718/5689/8463/6046/5684/5682/1499/10018/1029/864/5690/5717/10197/7316/10213/865/1026/10413/6714/4609/4089/22938/8850/5711/1387/5687/5685/5708/5692/5686/2033/595/5702/7157/5719/6233/7311/3845/5694/4851/5693/5691/3676/7314/4193 46 West_Nile_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 45/1715 93/10654 3.1432023388638743e-13 3.540804002241527e-12 1.5581686808043139e-12 54106/8454/3665/3725/8945/5601/351/9252/4790/5604/5594/246330/7099/4615/5528/7316/79155/5970/177/3146/5519/23291/929/5602/3656/6195/3654/7189/5609/6233/51135/2353/6196/7311/5518/1386/6197/5599/7334/51231/51284/7314/5595/5515/5516 45 West_Nile_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 45/1715 93/10654 3.1432023388638743e-13 3.540804002241527e-12 1.5581686808043139e-12 54106/8454/3665/3725/8945/5601/351/9252/4790/5604/5594/246330/7099/4615/5528/7316/79155/5970/177/3146/5519/23291/929/5602/3656/6195/3654/7189/5609/6233/51135/2353/6196/7311/5518/1386/6197/5599/7334/51231/51284/7314/5595/5515/5516 45 West_Nile_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 55/1715 129/10654 5.656251660024378e-13 6.317745498230619e-12 2.7801914939102876e-12 8454/3665/3725/8945/5601/351/9252/4790/5604/11213/7321/29110/5594/1785/246330/841/7099/4615/5528/7316/79155/5970/59307/177/8651/26052/3146/5519/23291/929/5602/3656/6195/3661/695/3654/7189/5609/6233/51135/2353/6196/7311/5518/1386/6197/5599/7334/7097/5781/51231/7314/5595/5515/5516 55 West_Nile_virus R-HSA-168898 Toll-like Receptor Cascades 62/1715 155/10654 6.067921781060437e-13 6.720605804569459e-12 2.957474481525255e-12 54106/8454/3665/3725/8945/5601/351/9252/4790/5604/11213/7321/29110/5594/1785/246330/841/7099/4615/7098/5528/7316/79155/5970/59307/6279/177/8651/26052/3146/5519/23291/2244/929/5602/3656/6195/3661/695/3654/7189/5609/6233/2266/51135/2353/6196/7311/5518/2243/1386/6197/5599/7334/7097/5781/51231/51284/7314/5595/5515/5516 62 West_Nile_virus R-HSA-5654719 SHC-mediated cascade:FGFR4 18/1715 20/10654 6.688531077219512e-13 7.285523933698609e-12 3.206072747758113e-12 4893/6464/8823/8074/8817/2254/152831/2249/26281/2247/9965/2264/6654/2885/2246/2251/3845/3265 18 West_Nile_virus R-HSA-5654720 PI-3K cascade:FGFR4 18/1715 20/10654 6.688531077219512e-13 7.285523933698609e-12 3.206072747758113e-12 5295/5290/8823/8074/8817/2254/152831/2249/26281/10818/2247/9965/2264/2885/2246/2251/2549/5781 18 West_Nile_virus R-HSA-442982 Ras activation upon Ca2+ influx through NMDA receptor 19/1715 22/10654 7.334205089369105e-13 7.923346153924984e-12 3.4867532392082634e-12 5923/818/815/4893/2904/817/2902/816/1741/2906/1742/1739/88/1740/3845/3265/801/5924/4747 19 West_Nile_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 44/1715 92/10654 9.665498963837997e-13 1.0357014336860553e-11 4.5577149585577546e-12 54106/8454/3725/8945/5601/351/9252/4790/5604/5594/246330/7099/4615/5528/7316/79155/5970/177/3146/5519/23291/929/5602/3656/6195/3654/7189/5609/6233/51135/2353/6196/7311/5518/1386/6197/5599/7334/51231/51284/7314/5595/5515/5516 44 West_Nile_virus R-HSA-8853659 RET signaling 27/1715 41/10654 1.1080322837372408e-12 1.1777310886820028e-11 5.182731649738707e-12 5295/2674/6464/5290/5291/5578/2675/4902/2676/2668/6714/10818/8503/64096/53358/5979/6654/2885/8660/9846/5293/9048/5296/2549/5623/5781/9046 27 West_Nile_virus R-HSA-354194 GRB2:SOS provides linkage to MAPK signaling for Integrins 15/1715 15/10654 1.1991924309174773e-12 1.2644284991593882e-11 5.5642528794570946e-012 5747/3674/7094/5908/54518/6714/2244/2335/3690/6654/2885/2266/5906/2243/7450 15 West_Nile_virus R-HSA-76002 Platelet activation, signaling and aggregation 88/1715 262/10654 1.4110250566046556e-12 1.4759770036547113e-11 6.4951947050055585e-12 5295/5777/5099/5590/351/1072/6464/5290/5579/5770/5291/5747/59345/2770/207/3674/26090/7094/7422/5578/5594/409/5908/3082/7414/10490/334/7534/54518/10125/1950/51706/308/6850/6714/710/6647/7273/8503/146850/226/4067/374354/2244/1893/3309/2335/5294/2534/3690/408/2783/2784/2768/1445/2782/998/2776/5894/2771/2/94121/10487/6654/2885/5580/88/2266/10235/5906/3932/5155/2243/7450/387/5296/5581/29789/801/350/5781/9002/5627/2773/6814/5879/5595/2787 88 West_Nile_virus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 40/1715 80/10654 1.705058764493558e-12 1.7695019303956768e-11 7.786882546506013e-12 8454/5718/1017/5689/8945/26271/5684/5682/7321/8697/5690/5717/10197/8881/7316/10213/890/983/5711/5687/5685/5708/5692/5686/5702/51529/5719/64682/29945/10393/6233/7311/9184/5347/29882/5694/5693/5691/7314/996 40 West_Nile_virus R-HSA-194138 Signaling by VEGF 48/1715 107/10654 1.777705195675204e-12 1.8304808186718117e-11 8.05522666790327e-12 5295/5590/4893/5290/71/5579/5291/1495/1499/6461/5747/207/7422/10458/5578/3315/5921/1500/10768/6714/1003/10163/3320/55845/5063/2534/9475/3690/3728/5603/998/79109/5580/2475/23191/6093/387/60/5296/3845/3265/5058/801/8877/5062/5879/253260/25759 48 West_Nile_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 45/1715 97/10654 2.0617842597458648e-12 2.092495871961313e-11 9.208251940345688e-12 54106/8454/3665/3725/8945/5601/351/9252/4790/5604/5594/246330/7099/4615/5528/7316/79155/5970/177/3146/5519/23291/929/5602/3656/6195/3654/7189/5609/6233/51135/2353/6196/7311/5518/1386/6197/5599/7334/51231/51284/7314/5595/5515/5516 45 West_Nile_virus R-HSA-109581 Apoptosis 67/1715 178/10654 2.0639185383533438e-12 2.092495871961313e-11 9.208251940345688e-12 4000/5718/5689/596/5684/22985/219699/5682/1499/10018/7531/5747/1029/842/55075/7532/207/10971/5690/5594/10059/5717/7533/2810/118/1829/841/10197/7099/7534/100506658/7316/10213/6774/54205/3146/5711/10134/5687/999/598/836/5685/929/5708/5692/5686/5702/7157/5719/4001/6233/5580/6709/6093/7311/839/840/5599/5694/5062/5693/140735/5691/7529/7314/5595 67 West_Nile_virus R-HSA-446652 Interleukin-1 family signaling 57/1715 140/10654 2.1935753172811647e-12 2.206971197081355e-11 9.712012855137982e-12 8454/3557/5718/834/5689/5777/8945/5684/351/4790/5682/5604/11213/29110/5690/3553/8878/54472/5717/246330/10197/4615/7316/10213/9978/79155/6774/5970/59307/177/3146/5711/3552/5687/23291/5685/5708/5692/5686/3656/5702/5719/3654/7189/6233/51135/7311/5599/5784/7334/5694/5781/5693/5691/3554/7314/3556 57 West_Nile_virus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 35/1715 65/10654 2.591164227942819e-12 2.587238221536845e-11 1.138541857732451e-11 10450/6118/6917/5434/5440/902/27339/5430/5436/5441/5438/5431/8450/5435/7316/9978/5433/5426/6119/5437/5427/5985/2033/2068/5439/2071/6233/7311/56949/9716/6117/57461/5432/7314/8451 35 West_Nile_virus R-HSA-1643713 Signaling by EGFR in Cancer 20/1715 25/10654 2.9010355357650183e-12 2.874860779051349e-11 1.2651132411606849e-11 5295/1839/4893/6464/685/5290/2069/7316/1950/3320/6654/6233/2885/7311/1956/3845/2549/3265/11140/7314 20 West_Nile_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 39/1715 78/10654 3.2362520238125855e-12 3.1831195278992446e-11 1.400765801351716e-11 3443/3665/3441/351/4790/7321/29110/57506/9636/3449/841/7706/3444/7316/5970/177/3146/23586/1387/3451/843/3448/2033/64135/3440/83737/3661/9246/7189/6233/7311/5094/5300/3452/1540/3456/3446/7314/3445 39 West_Nile_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 42/1715 88/10654 3.467394887375999e-12 3.385204786341901e-11 1.489695581243022e-11 5718/5689/5684/5682/3842/207/5690/5578/3184/5717/3315/26986/10197/7534/8125/7538/7316/10213/8741/5711/5687/5685/5708/5692/5686/1981/5702/5719/6233/5580/7514/7311/5694/3312/8570/23016/5693/54512/5691/7529/7314/1994 42 West_Nile_virus R-HSA-5654693 FRS-mediated FGFR1 signaling 19/1715 23/10654 3.5789692463963222e-12 3.468442254963495e-11 1.526325119786667e-11 4893/8074/10817/2260/2254/2249/26281/10818/2248/2247/2255/27006/6654/2885/2246/2251/3845/3265/5781 19 West_Nile_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 17/1715 19/10654 3.7745034489466466e-12 3.604924308486725e-11 1.5863855075283006e-11 5295/4893/6464/5290/7316/1950/3320/6654/6233/2885/7311/1956/3845/2549/3265/11140/7314 17 West_Nile_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 17/1715 19/10654 3.7745034489466466e-12 3.604924308486725e-11 1.5863855075283006e-11 5295/4893/6464/5290/7316/1950/3320/6654/6233/2885/7311/1956/3845/2549/3265/11140/7314 17 West_Nile_virus R-HSA-6782135 Dual incision in TC-NER 35/1715 66/10654 4.669967686187755e-12 4.428070079421195e-11 1.9486196100639553e-11 10450/6118/6917/5434/5440/902/27339/5430/5436/5441/5438/5431/8450/5435/7316/9978/5433/5426/6119/5437/5427/5985/2033/2068/5439/2071/6233/7311/56949/9716/6117/57461/5432/7314/8451 35 West_Nile_virus R-HSA-166166 MyD88-independent TLR4 cascade 45/1715 99/10654 5.0039361700627645e-12 4.677438207193421e-11 2.0583567224371658e-11 8454/3665/3725/8945/5601/351/9252/4790/5604/7321/29110/5594/841/7099/5528/7316/79155/5970/177/3146/5519/23291/929/5602/3656/6195/3661/3654/7189/5609/6233/2353/6196/7311/5518/1386/6197/5599/7334/5781/51231/7314/5595/5515/5516 45 West_Nile_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 45/1715 99/10654 5.0039361700627645e-12 4.677438207193421e-11 2.0583567224371658e-11 8454/3665/3725/8945/5601/351/9252/4790/5604/7321/29110/5594/841/7099/5528/7316/79155/5970/177/3146/5519/23291/929/5602/3656/6195/3661/3654/7189/5609/6233/2353/6196/7311/5518/1386/6197/5599/7334/5781/51231/7314/5595/5515/5516 45 West_Nile_virus R-HSA-5357801 Programmed Cell Death 67/1715 181/10654 5.051047979840411e-12 4.688226223542015e-11 2.063104104441858e-11 4000/5718/5689/596/5684/22985/219699/5682/1499/10018/7531/5747/1029/842/55075/7532/207/10971/5690/5594/10059/5717/7533/2810/118/1829/841/10197/7099/7534/100506658/7316/10213/6774/54205/3146/5711/10134/5687/999/598/836/5685/929/5708/5692/5686/5702/7157/5719/4001/6233/5580/6709/6093/7311/839/840/5599/5694/5062/5693/140735/5691/7529/7314/5595 67 West_Nile_virus R-HSA-2262752 Cellular responses to stress 135/1715 479/10654 5.716153349452576e-12 5.2684546255793675e-11 2.3184398200576884e-11 5718/1017/23165/818/6118/5689/3725/4928/815/25913/81929/1019/5684/5601/4790/55706/7175/5682/9631/9448/3159/7531/1029/1915/1783/7321/2146/817/6045/9550/7422/8697/5690/9114/5594/9530/5717/3091/50488/545/79023/10381/57122/10197/3576/3313/8881/7316/10213/9978/890/527/6774/5970/1026/9532/54205/832/9688/6647/6119/5711/3552/1387/4683/5687/245972/2908/144577/5685/3309/5708/3320/5602/5692/5686/2033/23512/6195/6767/816/533/7428/5702/10540/7157/8453/51529/8086/5719/4001/64682/29945/10393/8091/5609/10542/6233/3326/2475/55004/2353/6196/7311/538/57634/4343/8726/6117/10587/6197/29882/5599/6396/648/54583/5694/3312/3456/405/3569/64121/57521/5693/10641/140735/5691/51382/7314/51164/996/51182/5595/4193/23043 135 West_Nile_virus R-HSA-2555396 Mitotic Metaphase and Anaphase 72/1715 202/10654 6.680601606991201e-12 6.114606193065558e-11 2.6907978694825672e-11 4000/5718/5689/5905/4928/26271/81929/5684/55143/5682/5525/1783/7321/5526/8697/5690/9212/5717/79023/10381/57122/64105/10197/6232/332/7443/8881/5528/7316/10213/5501/5519/5711/5687/5685/7444/5708/5692/5686/8243/9126/5529/5702/51529/2010/5719/4001/64682/29945/10393/11004/23592/6233/5527/7514/7311/9184/5518/5347/113130/29882/6396/5694/25909/7112/5693/140735/5691/7314/996/5515/5516 72 West_Nile_virus R-HSA-1250347 SHC1 events in ERBB4 signaling 14/1715 14/10654 7.501121378578463e-12 6.818260673769942e-11 3.000448551431385e-11 1839/4893/6464/685/2069/145957/3084/2066/6654/9542/2885/10718/3845/3265 14 West_Nile_virus R-HSA-5655302 Signaling by FGFR1 in disease 25/1715 38/10654 7.99298809525262e-12 7.215587883248598e-11 3.175296640579808e-11 5295/8805/4893/11052/5290/9530/8074/2260/2254/6774/2249/6772/26281/10818/2247/6654/2885/2246/2251/9846/11160/3845/2549/3265/7750 25 West_Nile_virus R-HSA-8868773 rRNA processing in the nucleus and cytosol 70/1715 195/10654 8.98085062955709e-12 8.052218455616493e-11 3.543464874247015e-11 9136/6138/6144/2091/6203/55651/55813/6194/6234/6191/6128/6132/6147/25879/6129/27292/6222/6152/6136/10528/6125/4839/6224/6146/6154/6141/88745/51602/6232/134430/6134/6160/55272/92856/5394/6205/6165/6142/9790/51077/6156/6235/10199/6124/6207/6139/6233/7311/6223/25873/83732/55505/3921/6188/6135/6201/6161/54881/51202/6187/4691/23016/6168/6208/54512/6157/6170/200916/6122/6230 70 West_Nile_virus R-HSA-9009391 Extra-nuclear estrogen signaling 38/1715 77/10654 1.0264371370800869e-11 9.140838828861855e-11 4.0225239155841245e-11 5295/596/5590/1839/4893/6464/685/5290/5747/59345/2770/207/5594/2069/3315/2100/1950/6714/2099/8503/3320/595/2783/2784/2782/2771/7514/2353/1956/5296/3845/3265/801/8877/3480/2773/5595/2787 38 West_Nile_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 43/1715 94/10654 1.1454696729395159e-11 1.0132409590162967e-10 4.458875236945767e-11 8454/3665/3725/8945/5601/351/9252/4790/5604/7321/29110/5594/841/7098/5528/7316/79155/5970/177/3146/5519/23291/5602/3656/6195/3661/3654/7189/5609/6233/2353/6196/7311/5518/1386/6197/5599/7334/51231/7314/5595/5515/5516 43 West_Nile_virus R-HSA-72312 rRNA processing 72/1715 205/10654 1.493161914690674e-11 1.3119916023748725e-10 5.773559403470608e-11 60528/9136/6138/6144/2091/6203/55651/55813/6194/6234/6191/6128/6132/6147/25879/6129/3028/27292/6222/6152/6136/10528/6125/4839/6224/6146/6154/6141/88745/51602/6232/134430/6134/6160/55272/92856/5394/6205/6165/6142/9790/51077/6156/6235/10199/6124/6207/6139/6233/7311/6223/25873/83732/55505/3921/6188/6135/6201/6161/54881/51202/6187/4691/23016/6168/6208/54512/6157/6170/200916/6122/6230 72 West_Nile_virus R-HSA-68882 Mitotic Anaphase 71/1715 201/10654 1.5246321251150553e-11 1.3307716164911544e-10 5.856202864680345e-11 4000/5718/5689/5905/4928/81929/5684/55143/5682/5525/1783/7321/5526/8697/5690/9212/5717/79023/10381/57122/64105/10197/6232/332/7443/8881/5528/7316/10213/5501/5519/5711/5687/5685/7444/5708/5692/5686/8243/9126/5529/5702/51529/2010/5719/4001/64682/29945/10393/11004/23592/6233/5527/7514/7311/9184/5518/5347/113130/29882/6396/5694/25909/7112/5693/140735/5691/7314/996/5515/5516 71 West_Nile_virus R-HSA-5655332 Signaling by FGFR3 in disease 18/1715 22/10654 1.856127800844683e-11 1.5989388506622823e-10 7.036301467254354e-11 5295/4893/5290/8823/8074/8817/2254/2249/26281/10818/2261/2247/6654/2885/2246/3845/2549/3265 18 West_Nile_virus R-HSA-8853338 Signaling by FGFR3 point mutants in cancer 18/1715 22/10654 1.856127800844683e-11 1.5989388506622823e-10 7.036301467254354e-11 5295/4893/5290/8823/8074/8817/2254/2249/26281/10818/2261/2247/6654/2885/2246/3845/2549/3265 18 West_Nile_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 40/1715 85/10654 1.9872719919287782e-11 1.678990054719314e-10 7.388575354606996e-11 8454/3725/8945/5601/351/9252/4790/5604/5594/246330/4615/5528/7316/79155/5970/177/3146/5519/23291/5602/3656/6195/3654/7189/5609/6233/51135/2353/6196/7311/5518/1386/6197/5599/7334/51231/7314/5595/5515/5516 40 West_Nile_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 40/1715 85/10654 1.9872719919287782e-11 1.678990054719314e-10 7.388575354606996e-11 8454/3725/8945/5601/351/9252/4790/5604/5594/246330/4615/5528/7316/79155/5970/177/3146/5519/23291/5602/3656/6195/3654/7189/5609/6233/51135/2353/6196/7311/5518/1386/6197/5599/7334/51231/7314/5595/5515/5516 40 West_Nile_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 40/1715 85/10654 1.9872719919287782e-11 1.678990054719314e-10 7.388575354606996e-11 8454/3725/8945/5601/351/9252/4790/5604/5594/246330/4615/5528/7316/79155/5970/177/3146/5519/23291/5602/3656/6195/3654/7189/5609/6233/51135/2353/6196/7311/5518/1386/6197/5599/7334/51231/7314/5595/5515/5516 40 West_Nile_virus R-HSA-5654706 FRS-mediated FGFR3 signaling 17/1715 20/10654 2.1373188715886568e-11 1.794258772454681e-10 7.895827678480387e-11 4893/8823/8074/8817/10817/2254/2249/26281/10818/2261/2247/6654/2885/2246/3845/3265/5781 17 West_Nile_virus R-HSA-933541 TRAF6 mediated IRF7 activation 21/1715 29/10654 2.2757911765005995e-11 1.8984131459669558e-10 8.35417014158448e-11 3443/3665/3441/29110/57506/3449/7706/3444/23586/1387/3451/3448/2033/64135/3440/3661/7189/3452/3456/3446/3445 21 West_Nile_virus R-HSA-187687 Signalling to ERKs 23/1715 34/10654 2.33441247394204e-11 1.9350664406639049e-10 8.515466886077882e-11 4893/6464/5899/5604/5594/673/57498/6714/5605/10818/5898/4914/53358/5603/6654/2885/5900/5906/3845/3265/7529/5595/25759 23 West_Nile_virus R-HSA-3928662 EPHB-mediated forward signaling 26/1715 42/10654 2.3714375004189693e-11 1.9534716409701262e-10 8.596460939018763e-11 1072/71/2904/5747/1947/7074/1949/5921/2902/10094/6714/4067/2534/9475/998/1948/2048/7525/10097/6093/387/60/3265/5058/10109/5879 26 West_Nile_virus R-HSA-8953897 Cellular responses to external stimuli 136/1715 493/10654 2.5334489523773912e-11 2.0739662852381377e-10 9.126710511670107e-11 5718/1017/23165/818/6118/5689/3725/4928/815/25913/81929/1019/5684/5601/4790/55706/7175/5682/9631/9448/3159/7531/1029/1915/1783/7321/2146/817/6045/9550/7422/8697/5690/9114/5594/9530/5717/3091/50488/545/79023/10381/57122/10197/3576/3313/8881/7316/10213/9978/890/527/6774/5970/1026/9532/54205/832/9688/6647/6119/5711/3552/1387/4683/5687/245972/2908/144577/5685/3309/5708/3320/5602/5692/5686/2033/23512/6195/6767/816/533/7428/5702/10540/7157/8453/51529/8086/5719/4001/64682/29945/10393/8091/5609/10542/6233/3326/2475/55004/2353/6196/7311/538/57634/4343/8726/6117/4520/10587/6197/29882/5599/6396/648/54583/5694/3312/3456/405/3569/64121/57521/5693/10641/140735/5691/51382/7314/51164/996/51182/5595/4193/23043 136 West_Nile_virus R-HSA-69620 Cell Cycle Checkpoints 92/1715 293/10654 3.150297608230486e-11 2.56301990595542e-10 1.127884328872643e-10 5718/1017/6118/5689/5905/4928/81929/5684/55143/5682/5525/7531/1029/1783/7486/7321/5526/7532/10971/8697/5690/9212/5717/7533/2810/545/79023/9133/57122/64105/10197/6232/7534/332/580/8881/5528/7316/10213/4174/5501/890/983/1026/4171/5519/6119/5711/4683/5687/5685/5708/5692/5985/5686/5529/1111/5702/7157/51529/5719/64682/29945/10393/11004/6233/5527/672/7514/7158/23595/7311/9184/5518/5347/6117/29882/6396/7334/5694/25909/5810/5693/140735/4999/5691/7529/7314/996/4193/5515/5516 92 West_Nile_virus R-HSA-162909 Host Interactions of HIV factors 52/1715 129/10654 3.180799567105573e-11 2.571959404567574e-10 1.1318182508719218e-10 5718/23165/5689/5905/8945/1173/4928/81929/5684/8065/55706/7175/5682/9631/3159/5690/5717/4869/79023/57122/10197/7316/10213/9978/920/3055/9688/5711/5687/5685/5708/5692/5686/2534/5702/5902/8086/5719/6233/7514/1025/7311/3932/6396/375/5694/55690/5062/5693/5691/7314/5879 52 West_Nile_virus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 37/1715 76/10654 3.212700852896364e-11 2.5819144659252486e-10 1.1361990821218846e-10 5718/5689/5684/5682/7321/8697/5690/5717/10197/8881/7316/10213/890/983/5711/5687/5685/5708/5692/5686/5702/51529/5719/64682/29945/10393/4751/6233/7311/9184/5347/29882/5694/5693/5691/7314/996 37 West_Nile_virus R-HSA-162587 HIV Life Cycle 58/1715 152/10654 3.3276713462129675e-11 2.6581035359446614e-10 1.1697268974566797e-10 23165/5905/4928/2963/6917/81929/5434/5440/902/55706/7175/79643/9631/3159/2959/5430/5436/7520/79023/57122/5441/91782/5438/3981/5431/5435/4686/7316/5433/6872/2960/920/9688/8148/2962/23327/5437/89853/83860/2068/5439/2071/5902/8086/6233/7514/1025/7311/93343/11198/6396/2547/2961/5432/22916/2957/7314/25920 58 West_Nile_virus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 36/1715 73/10654 3.695710877003599e-11 2.9189201514506447e-10 1.2845020393333642e-10 5718/5689/5684/5682/7321/8697/5690/5717/10197/8881/7316/10213/890/983/5711/5687/5685/5708/5692/5686/5702/51529/5719/64682/29945/10393/4751/6233/7311/9184/29882/5694/5693/5691/7314/996 36 West_Nile_virus R-HSA-5696398 Nucleotide Excision Repair 47/1715 111/10654 3.6984800098046865e-11 2.9189201514506447e-10 1.2845020393333642e-10 10450/9318/6118/6917/5434/5440/902/27339/5430/5436/5441/86/5438/5431/8450/5435/7316/9978/5433/64708/5426/10980/283899/6119/5437/5427/5985/10920/2033/2068/5439/10987/2071/7329/6233/7311/56949/60/8607/9716/6117/7334/57461/5432/7314/51138/8451 47 West_Nile_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 46/1715 108/10654 4.679680046529479e-11 3.671320417455865e-10 1.6156038255875583e-10 5295/6095/3605/7124/7291/596/3561/7412/207/5292/9021/7422/3553/4582/3082/5743/3091/3383/301/3576/332/3662/3688/6774/1026/3718/6772/8651/4609/3552/3717/598/2247/3320/4843/2335/595/7157/3716/2353/3312/7297/3569/3162/4170/3586 46 West_Nile_virus R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 66/1715 185/10654 4.851071555120897e-11 3.7832617216860015e-10 1.6648647940651603e-10 9136/6138/6144/2091/6203/55813/6194/6234/6191/6128/6132/6147/25879/6129/6222/6152/6136/10528/6125/6224/6146/6154/6141/88745/51602/6232/134430/6134/6160/55272/92856/5394/6205/6165/6142/9790/51077/6156/6235/10199/6124/6207/6139/6233/7311/6223/25873/83732/3921/6188/6135/6201/6161/54881/51202/6187/4691/23016/6168/6208/54512/6157/6170/200916/6122/6230 66 West_Nile_virus R-HSA-1433557 Signaling by SCF-KIT 26/1715 43/10654 5.083081790213502e-11 3.9408834114714093e-10 1.7342279048963716e-10 5295/5777/9402/4893/5290/3815/5578/6774/6772/6714/8651/8503/4067/3717/2534/1111/6654/2885/7525/9846/3932/5296/3845/3265/5781/5879 26 West_Nile_virus R-HSA-9620244 Long-term potentiation 19/1715 25/10654 5.156454004147251e-11 3.974389694424606e-10 1.7489727031610557e-10 818/815/2904/817/2902/6714/2905/2903/3084/816/2066/1741/2906/1742/1739/88/1740/801/4747 19 West_Nile_virus R-HSA-450294 MAP kinase activation 33/1715 64/10654 5.196210604329203e-11 3.9817474282010986e-10 1.7522105526226383e-10 8454/3725/8945/5601/9252/4790/5604/5594/5528/7316/79155/5519/23291/5602/3656/6195/3654/7189/5609/6233/2353/6196/7311/5518/1386/6197/5599/7334/51231/7314/5595/5515/5516 33 West_Nile_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 47/1715 112/10654 5.392179561693105e-11 4.108030440642493e-10 1.8077827432265903e-10 5295/8454/5718/5689/5777/8945/5684/4893/4790/5579/5682/5690/5532/5717/10197/7316/10213/10125/5970/6850/10768/25780/5711/5687/4067/23291/5685/5708/5692/5686/2534/5702/695/5719/6654/6233/2885/7311/5293/3845/5694/3265/801/5693/5691/7314/6786 47 West_Nile_virus R-HSA-5621481 C-type lectin receptors (CLRs) 55/1715 142/10654 5.4690747088903284e-11 4.142666934665203e-10 1.823024902963443e-10 8454/5718/5689/8945/5684/9252/4893/4790/5682/7321/5690/3553/5532/4582/5717/841/10197/7316/10213/5970/6850/10768/6714/5711/1387/5687/4067/23291/5685/5708/5692/5686/5063/2534/2033/5702/9040/5894/5719/7189/200958/6233/5580/30835/7311/3845/7334/5694/3265/5058/801/5062/5693/5691/7314 55 West_Nile_virus R-HSA-166658 Complement cascade 31/1715 58/10654 5.981514614458115e-11 4.454031786359207e-10 1.9600443369410771e-10 5648/727/629/10584/722/1378/10747/1604/717/731/712/710/716/715/78989/3426/2220/721/975/725/732/713/2219/720/4179/8547/714/4153/729/5627/718 31 West_Nile_virus R-HSA-72649 Translation initiation complex formation 31/1715 58/10654 5.981514614458115e-11 4.454031786359207e-10 1.9600443369410771e-10 6203/6194/1965/6234/6191/8666/6222/8668/6224/26986/6232/8661/6205/8663/8894/1981/6235/1973/6207/1977/6233/6223/8664/3646/3921/6188/6201/6187/6208/1968/6230 31 West_Nile_virus R-HSA-72702 Ribosomal scanning and start codon recognition 31/1715 58/10654 5.981514614458115e-11 4.454031786359207e-10 1.9600443369410771e-10 6203/6194/1965/6234/6191/8666/6222/1983/8668/6224/6232/8661/6205/8663/8894/1981/6235/1973/6207/1977/6233/6223/8664/3646/3921/6188/6201/6187/6208/1968/6230 31 West_Nile_virus R-HSA-8941858 Regulation of RUNX3 expression and activity 30/1715 55/10654 6.200792569891518e-11 4.591373374784843e-10 2.020482972211843e-10 57154/5718/5689/5684/5682/1029/864/5690/5717/10197/7316/10213/865/6714/5711/5687/5685/5708/5692/5686/2033/5702/5719/6233/7311/5694/5693/5691/7314/4193 30 West_Nile_virus R-HSA-166663 Initial triggering of complement 18/1715 23/10654 7.249758955182892e-11 5.33809067202852e-10 2.349083907265965e-10 5648/629/10584/10747/717/712/716/715/78989/2220/721/713/2219/720/8547/714/4153/718 18 West_Nile_virus R-HSA-5654688 SHC-mediated cascade:FGFR1 17/1715 21/10654 9.531613189125521e-11 6.932399501055346e-10 3.0506765634386193e-10 4893/6464/8074/2260/2254/2249/26281/2248/2247/2255/27006/6654/2885/2246/2251/3845/3265 17 West_Nile_virus R-HSA-5654689 PI-3K cascade:FGFR1 17/1715 21/10654 9.531613189125521e-11 6.932399501055346e-10 3.0506765634386193e-10 5295/5290/8074/2260/2254/2249/26281/10818/2248/2247/2255/27006/2885/2246/2251/2549/5781 17 West_Nile_virus R-HSA-6785631 ERBB2 Regulates Cell Motility 14/1715 15/10654 9.572812664583254e-11 6.932399501055346e-10 3.0506765634386193e-10 1839/685/2065/2069/2064/1950/51072/145957/3084/2066/9542/10718/387/1956 14 West_Nile_virus R-HSA-8878166 Transcriptional regulation by RUNX2 49/1715 121/10654 9.69951901208359e-11 6.985773802145449e-10 3.0741644956330506e-10 8454/57154/5718/5689/7291/1019/5684/5682/23462/207/5690/5594/5717/100526737/3958/3678/10197/2737/7316/10213/9978/865/983/1026/10413/6772/6714/2099/4089/5711/5687/2908/5685/5708/5692/5686/595/55294/5702/5719/6233/7525/7311/10432/5694/5693/5691/7314/5595 49 West_Nile_virus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 36/1715 75/10654 9.918391980748652e-11 7.104587299253653e-10 3.126449646105553e-10 5718/5689/5684/5682/7321/8697/5690/5717/10197/8881/7316/10213/890/983/5711/5687/5685/5708/5692/5686/5702/51529/5719/64682/29945/10393/4751/6233/7311/9184/29882/5694/5693/5691/7314/996 36 West_Nile_virus R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 31/1715 59/10654 1.0674324660431864e-10 7.604735082404971e-10 3.3465450286759356e-10 6203/6194/1965/6234/6191/8666/6222/8668/6224/26986/6232/8661/6205/8663/8894/1981/6235/1973/6207/1977/6233/6223/8664/3646/3921/6188/6201/6187/6208/1968/6230 31 West_Nile_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 38/1715 82/10654 1.1203841544332458e-10 7.939066212596871e-10 3.493671019200444e-10 8454/5718/5689/8945/5684/5682/1499/5525/5526/10023/1452/5690/5717/10197/5528/7316/10213/9978/5519/5711/5687/5685/5708/5692/5686/5529/5702/5719/6233/5527/7311/5518/5694/5693/5691/7314/5515/5516 38 West_Nile_virus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 35/1715 72/10654 1.1553444757951162e-10 8.099702229244485e-10 3.56436061681472e-10 5718/5689/5684/5682/7321/8697/5690/9212/5717/10197/8881/7316/10213/6790/5711/5687/5685/5708/5692/5686/5702/51529/5719/64682/29945/10393/6233/7311/5347/29882/5694/5693/5691/7314/996 35 West_Nile_virus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 35/1715 72/10654 1.1553444757951162e-10 8.099702229244485e-10 3.56436061681472e-10 5718/5689/5684/5682/7321/8697/5690/5717/10197/8881/7316/10213/890/983/5711/5687/5685/5708/5692/5686/5702/51529/5719/64682/29945/10393/6233/7311/9184/29882/5694/5693/5691/7314/996 35 West_Nile_virus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 32/1715 63/10654 1.6965933901475403e-10 1.1831270308013006e-9 5.20647707029404e-10 5718/5689/5684/5682/7321/8697/5690/5717/10197/8881/7316/10213/5711/5687/5685/5708/5692/5686/5702/51529/5719/64682/29945/10393/6233/7311/29882/5694/5693/5691/7314/996 32 West_Nile_virus R-HSA-69052 Switching of origins to a post-replicative state 40/1715 90/10654 1.7901045507243654e-10 1.2417672620287967e-9 5.46452968115859e-10 8454/5718/1017/5689/5684/5682/7321/8697/5690/5717/10197/8881/7316/10213/9978/4174/890/4171/5711/5687/5685/5708/5692/5686/5702/51529/5719/64682/29945/10393/6233/23595/7311/29882/5694/5693/4999/5691/7314/996 40 West_Nile_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 37/1715 80/10654 2.1140597241736507e-10 1.4588118934350114e-9 6.419657801155589e-10 23165/4928/3838/81929/55706/7175/9631/9636/79023/57122/1982/7706/7316/3434/6772/9688/23586/8672/6059/1981/1973/3661/8086/9246/1977/4599/6233/3716/7311/5300/9775/4940/6396/7334/4938/7314/5595 37 West_Nile_virus R-HSA-388841 Costimulation by the CD28 family 34/1715 70/10654 2.1909801429581613e-10 1.5040165773014877e-9 6.618585848519445e-10 5295/5777/9402/5290/5525/5526/207/5528/920/6714/5519/8503/29126/4067/5063/2534/5529/1445/998/5527/2885/7525/79109/2475/3932/5518/5296/5058/5781/5062/5879/253260/5515/5516 34 West_Nile_virus R-HSA-69206 G1/S Transition 51/1715 131/10654 2.2049201705380962e-10 1.5057434117975186e-9 6.626184968456456e-10 8454/5718/1017/6118/5689/26271/1019/5684/902/5682/207/5690/5717/10197/286826/7316/10213/5422/4174/890/983/1026/5426/4171/4609/5519/6119/5711/5687/5427/5685/5708/5692/5686/595/5702/5719/6233/7298/23595/7311/5518/6117/1719/5694/5693/4999/5691/7314/5515/5516 51 West_Nile_virus R-HSA-162599 Late Phase of HIV Life Cycle 53/1715 139/10654 2.422528173660149e-10 1.6458206870536476e-9 7.242610003726219e-10 23165/5905/4928/2963/6917/81929/5434/5440/902/55706/7175/79643/9631/2959/5430/5436/79023/57122/5441/91782/5438/5431/5435/4686/7316/5433/6872/2960/9688/8148/2962/23327/5437/89853/83860/2068/5439/2071/5902/8086/6233/7514/1025/7311/93343/11198/6396/2961/5432/22916/2957/7314/25920 53 West_Nile_virus R-HSA-8863795 Downregulation of ERBB2 signaling 20/1715 29/10654 2.834834252567981e-10 1.9160572025049225e-9 8.43181469994579e-10 1839/8065/685/2065/207/2069/2064/7316/1950/145957/3320/3084/2066/9542/6233/10718/7311/1956/11140/7314 20 West_Nile_virus R-HSA-72766 Translation 89/1715 291/10654 3.083756365931591e-10 2.0736688215805288e-9 9.125401491022054e-10 6138/6144/10352/6203/51253/8891/6194/2107/1965/6234/6191/6128/10952/6132/1938/6147/9521/8666/6129/1915/9255/6222/1983/6152/6136/8668/6125/6727/6224/6146/6154/6141/26986/6232/58477/2935/6134/6160/55699/8661/55157/29927/64963/9669/6729/6205/6165/6142/8663/28972/8894/7965/1981/6156/6235/1973/51263/6124/740/6207/1977/6139/6745/6726/6233/7311/6223/25873/8664/3646/6730/3921/6188/26589/9789/6135/6201/6161/6187/6168/6208/6157/6170/7284/8892/200916/6122/1968/6230 89 West_Nile_virus R-HSA-168325 Viral Messenger RNA Synthesis 25/1715 43/10654 3.9281355465510004e-10 2.6280622590630553e-9 1.1565069121825279e-9 23165/4928/2963/81929/5434/5440/55706/7175/9631/5430/5436/79023/57122/5441/5438/5431/5435/5433/9688/2962/5437/5439/8086/6396/5432 25 West_Nile_virus R-HSA-3700989 Transcriptional Regulation by TP53 105/1715 365/10654 4.061587858850647e-10 2.7036226252349253e-9 1.1897580596633208e-9 1017/834/6118/3725/2963/6917/5434/5440/5305/902/7531/1029/7486/5430/7532/207/10971/5436/1345/55240/9212/835/4869/7533/2810/1460/4292/545/5441/7534/332/5438/580/5431/5435/7316/5433/6872/890/1457/983/1026/54205/6790/1108/8148/2962/5519/4514/6119/1387/4683/5437/83860/23019/843/2821/28984/6794/5985/54815/2033/5728/2068/5439/1111/2071/7157/1107/5371/10498/10542/6233/5527/79109/1349/2475/55004/672/1025/2353/7311/839/5518/1386/10419/5300/4343/6117/1340/11198/5810/64121/10397/5432/57521/7248/26155/7529/7314/253260/4193/5515/25920/5516 105 West_Nile_virus R-HSA-453279 Mitotic G1-G1/S phases 55/1715 149/10654 4.6473477168937615e-10 3.0779921059628025e-9 1.3545033546725537e-9 8454/5718/1017/6118/5689/26271/1019/5684/902/5682/1029/207/5690/5717/10197/286826/7316/10213/5422/4174/890/983/1026/5426/6714/4171/4609/5519/6119/5711/5687/5427/4067/3717/5685/5708/5692/5686/595/5702/5719/6233/7298/23595/7311/5518/6117/1719/5694/5693/4999/5691/7314/5515/5516 55 West_Nile_virus R-HSA-9013694 Signaling by NOTCH4 37/1715 82/10654 5.082189237013955e-10 3.349162707192196e-9 1.4738348787340471e-9 8454/5718/5689/5684/5682/23462/207/5690/5717/10197/7534/7316/10213/9978/102/22938/8850/5711/1387/5687/5685/5708/5692/5686/2033/55294/4853/5702/5719/6233/7311/5694/4851/5693/5663/5691/7314 37 West_Nile_virus R-HSA-166786 Creation of C4 and C2 activators 13/1715 14/10654 5.590494974323879e-10 3.6658071523178474e-9 1.6131776542825124e-9 5648/10584/10747/712/716/715/78989/2220/713/2219/8547/714/4153 13 West_Nile_virus R-HSA-1169408 ISG15 antiviral mechanism 34/1715 72/10654 5.71132446497225e-10 3.6899635513889345e-9 1.6238079361195615e-9 23165/4928/3838/81929/55706/7175/9631/9636/79023/57122/1982/7706/7316/3434/6772/9688/23586/8672/1981/1973/3661/8086/9246/1977/4599/6233/3716/7311/5300/9775/6396/7334/7314/5595 34 West_Nile_virus R-HSA-448424 Interleukin-17 signaling 34/1715 72/10654 5.71132446497225e-10 3.6899635513889345e-9 1.6238079361195615e-9 8454/3605/3725/8945/5601/9252/4790/5604/5594/5528/7316/79155/5519/23291/5602/3656/6195/3654/7189/5609/6233/2353/6196/7311/5518/1386/6197/5599/7334/51231/7314/5595/5515/5516 34 West_Nile_virus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 34/1715 72/10654 5.71132446497225e-10 3.6899635513889345e-9 1.6238079361195615e-9 5718/1017/5689/5684/5682/7321/8697/5690/5717/10197/8881/7316/10213/890/5711/5687/5685/5708/5692/5686/5702/51529/5719/64682/29945/10393/6233/7311/29882/5694/5693/5691/7314/996 34 West_Nile_virus R-HSA-5654704 SHC-mediated cascade:FGFR3 15/1715 18/10654 6.015584819019452e-10 3.84880620945031e-9 1.693708347102564e-9 4893/6464/8823/8074/8817/2254/2249/26281/2261/2247/6654/2885/2246/3845/3265 15 West_Nile_virus R-HSA-5654710 PI-3K cascade:FGFR3 15/1715 18/10654 6.015584819019452e-10 3.84880620945031e-9 1.693708347102564e-9 5295/5290/8823/8074/8817/2254/2249/26281/10818/2261/2247/2885/2246/2549/5781 15 West_Nile_virus R-HSA-69239 Synthesis of DNA 47/1715 119/10654 6.368057977981731e-10 4.054637881632812e-9 1.7842867764393255e-9 8454/5718/1017/6118/5689/5684/5682/7321/8697/5690/5717/10197/8881/7316/10213/5422/9978/4174/890/5426/4171/6119/5711/5687/5427/5685/5708/5692/5985/5686/5702/51529/5719/64682/29945/10393/6233/23595/7311/6117/29882/5694/5693/4999/5691/7314/996 47 West_Nile_virus R-HSA-1236974 ER-Phagosome pathway 37/1715 83/10654 7.763066725057617e-10 4.919097088281702e-9 2.164701298333374e-9 5718/8773/5689/5684/10952/5682/3107/5690/5717/811/10197/7099/4615/9554/7316/10213/29927/5711/9341/5687/5685/929/5708/5692/5686/5702/695/5719/6233/7311/5694/7097/8673/3105/5693/5691/7314 37 West_Nile_virus R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 17/1715 23/10654 1.1603402641255752e-9 7.31736109147133e-9 3.220083029630783e-9 2963/5434/5440/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/5439/5432/22916/25920 17 West_Nile_virus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 32/1715 67/10654 1.277619497375398e-9 7.985842523414933e-9 3.5142554351901827e-9 5718/5689/5684/5682/7321/8697/5690/5717/10197/8881/7316/10213/5711/5687/5685/5708/5692/5686/5702/51529/5719/64682/29945/10393/6233/7311/29882/5694/5693/5691/7314/996 32 West_Nile_virus R-HSA-9604323 Negative regulation of NOTCH4 signaling 28/1715 54/10654 1.2784618910778077e-9 7.985842523414933e-9 3.5142554351901827e-9 8454/5718/5689/5684/5682/207/5690/5717/10197/7534/7316/10213/9978/5711/5687/5685/5708/5692/5686/55294/5702/5719/6233/7311/5694/5693/5691/7314 28 West_Nile_virus R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 27/1715 51/10654 1.3768596642991044e-9 8.5599105544633e-9 3.766880213648493e-9 6203/6194/1965/6234/6191/8666/6222/8668/6224/6232/8661/6205/8663/8894/6235/6207/6233/6223/8664/3646/3921/6188/6201/6187/6208/1968/6230 27 West_Nile_virus R-HSA-69242 S Phase 57/1715 161/10654 1.4137413461850035e-9 8.747939409726923e-9 3.84962432294508e-9 8454/5718/1017/6118/5689/1019/5684/902/5682/7321/207/8697/5690/5717/10197/286826/8881/7316/10213/5422/9978/4174/890/1026/5426/4171/4609/6119/5711/5687/5427/5685/5708/5692/5985/5686/8243/9126/595/5702/51529/5719/64682/29945/10393/6233/23595/7311/113130/6117/29882/5694/5693/4999/5691/7314/996 57 West_Nile_virus R-HSA-2467813 Separation of Sister Chromatids 64/1715 190/10654 1.4552938848196894e-9 8.9629782251979e-9 3.944254454184204e-9 5718/5689/5905/4928/81929/5684/55143/5682/5525/1783/7321/5526/8697/5690/9212/5717/79023/10381/57122/64105/10197/6232/332/8881/5528/7316/10213/5501/5519/5711/5687/5685/5708/5692/5686/8243/9126/5529/5702/51529/5719/64682/29945/10393/11004/6233/5527/7514/7311/9184/5518/5347/113130/29882/6396/5694/25909/5693/140735/5691/7314/996/5515/5516 64 West_Nile_virus R-HSA-389513 CTLA4 inhibitory signaling 16/1715 21/10654 1.7285455777665118e-9 1.0596386379052384e-8 4.663053186532915e-9 5525/5526/207/5528/6714/5519/4067/2534/5529/5527/7525/3932/5518/5781/5515/5516 16 West_Nile_virus R-HSA-8851805 MET activates RAS signaling 11/1715 11/10654 1.8304259273929624e-9 1.1117517844718544e-8 4.892382663077964e-9 4893/6464/10048/3082/4233/6654/200958/2885/57610/3845/3265 11 West_Nile_virus R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 11/1715 11/10654 1.8304259273929624e-9 1.1117517844718544e-8 4.892382663077964e-9 627/4893/4915/10817/10818/4909/6654/2885/3845/3265/5781 11 West_Nile_virus R-HSA-1236394 Signaling by ERBB4 29/1715 58/10654 1.9684123333147907e-9 1.1900768143618781e-8 5.237060336342104e-9 5295/1839/4893/6464/685/5290/2065/2069/7316/1950/10413/6714/2099/145957/3084/2066/83737/1742/6654/9542/6233/2885/10718/7311/1956/3845/3265/5663/7314 29 West_Nile_virus R-HSA-373760 L1CAM interactions 46/1715 119/10654 2.208443489017711e-9 1.3290997801485584e-8 5.848845770001244e-9 1173/9252/6711/71/7430/6712/5604/10048/3674/5594/1785/1460/10381/3678/4478/2260/4684/3688/8650/1457/57731/6714/5605/26052/6710/3673/27330/3690/6195/6708/1741/2048/1742/1739/287/6709/51332/6196/24137/1956/60/6197/3312/5058/5879/5595 46 West_Nile_virus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 37/1715 86/10654 2.6165715990170723e-9 1.5675642579565915e-8 6.898234215590464e-9 5295/1072/5290/23646/71/5291/5747/4627/10458/4771/5594/2209/3055/6850/10768/10094/6714/10163/4067/3320/55845/2534/998/695/2885/7525/3326/5580/10097/23191/60/5296/5581/5058/10109/5879/5595 37 West_Nile_virus R-HSA-72086 mRNA Capping 19/1715 29/10654 3.0290952595512386e-9 1.8064921050174355e-8 7.949661767148047e-9 2963/5434/5440/902/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/2068/5439/2071/5432/22916 19 West_Nile_virus R-HSA-2033519 Activated point mutants of FGFR2 14/1715 17/10654 3.1424008891544695e-9 1.8656235909484644e-8 8.209876196890056e-9 8823/8074/8817/2254/2263/2249/26281/2248/2247/2255/27006/2246/2251/2252 14 West_Nile_virus R-HSA-8847993 ERBB2 Activates PTK6 Signaling 12/1715 13/10654 3.2470208088658414e-9 1.9190912224597213e-8 8.445166229337167e-9 1839/685/2065/2069/2064/1950/145957/3084/2066/9542/10718/1956 12 West_Nile_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 36/1715 83/10654 3.2838866790918794e-9 1.9322154656442397e-8 8.50292086550576e-9 8454/5718/5689/8945/5684/4893/4790/5579/5682/5690/5532/5717/10197/7316/10213/10125/5970/25780/5711/5687/23291/5685/5708/5692/5686/5702/5719/6233/7311/3845/5694/3265/801/5693/5691/7314 36 West_Nile_virus R-HSA-372708 p130Cas linkage to MAPK signaling for integrins 13/1715 15/10654 3.570638407544988e-9 2.0731724322221562e-8 9.123217076546667e-9 5747/3674/7094/5908/54518/6714/2244/2335/3690/2266/5906/2243/7450 13 West_Nile_virus R-HSA-5637810 Constitutive Signaling by EGFRvIII 13/1715 15/10654 3.570638407544988e-9 2.0731724322221562e-8 9.123217076546667e-9 5295/4893/6464/5290/1950/3320/6654/2885/1956/3845/2549/3265/11140 13 West_Nile_virus R-HSA-5637812 Signaling by EGFRvIII in Cancer 13/1715 15/10654 3.570638407544988e-9 2.0731724322221562e-8 9.123217076546667e-9 5295/4893/6464/5290/1950/3320/6654/2885/1956/3845/2549/3265/11140 13 West_Nile_virus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 28/1715 56/10654 3.7399342470841425e-9 2.1619444463407456e-8 9.513867821529836e-9 5718/5689/5684/5682/5690/3184/5717/3315/26986/10197/7316/10213/5711/5687/5685/5708/5692/5686/1981/5702/5719/6233/7311/5694/3312/5693/5691/7314 28 West_Nile_virus R-HSA-2871796 FCERI mediated MAPK activation 20/1715 32/10654 3.9073718106325325e-9 2.2488716359885058e-8 9.896400219069296e-9 3725/9402/5601/4893/6464/5594/6850/4067/5602/5609/6654/2885/2353/3845/5599/3265/5058/5062/5879/5595 20 West_Nile_virus R-HSA-191859 snRNP Assembly 27/1715 53/10654 4.1930964335887325e-9 2.3924247183852593e-8 1.0528120915504176e-8 23165/4928/81929/6635/6633/6632/11218/55706/7175/6606/9631/6637/79023/57122/4686/9688/51808/1207/79084/8086/6636/6634/10419/79833/6396/22916/6628 27 West_Nile_virus R-HSA-194441 Metabolism of non-coding RNA 27/1715 53/10654 4.1930964335887325e-9 2.3924247183852593e-8 1.0528120915504176e-8 23165/4928/81929/6635/6633/6632/11218/55706/7175/6606/9631/6637/79023/57122/4686/9688/51808/1207/79084/8086/6636/6634/10419/79833/6396/22916/6628 27 West_Nile_virus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 23/1715 41/10654 5.201020041674302e-9 2.9547174202270388e-8 1.3002550104185755e-8 23165/53981/4928/81929/55706/7175/9631/29894/79023/57122/81608/4686/8189/9688/10898/10189/10482/51692/8086/1977/6396/22916/55339 23 West_Nile_virus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 29/1715 60/10654 5.378876656894259e-9 3.034730723937391e-8 1.3354657207008246e-8 8454/5718/1017/5689/1019/5684/5682/5690/5717/10197/7316/10213/890/1026/5711/5687/5685/5708/5692/5686/595/5702/5719/6233/7311/5694/5693/5691/7314 29 West_Nile_virus R-HSA-912631 Regulation of signaling by CBL 16/1715 22/10654 5.38791342489643e-9 3.034730723937391e-8 1.3354657207008246e-8 5295/5290/5291/7316/3055/6850/8503/4067/2534/6233/2885/7525/7311/5293/5296/7314 16 West_Nile_virus R-HSA-1236975 Antigen processing-Cross presentation 40/1715 99/10654 5.499978868436921e-9 3.084668999404196e-8 1.3574415930610272e-8 5718/8773/5689/5684/10952/5682/3107/5690/5717/811/2209/10197/7099/4615/9554/7316/10213/29927/5711/9341/5687/5685/929/5708/5692/5686/5702/695/5719/9902/6233/4012/7311/5694/7097/8673/3105/5693/5691/7314 40 West_Nile_virus R-HSA-438064 Post NMDA receptor activation events 35/1715 81/10654 6.1191963710188205e-9 3.4174156004249176e-8 1.503870294572422e-8 5923/818/815/3838/4893/2904/817/5594/114/10381/5573/2902/6714/2905/27330/2903/3084/6195/816/2066/1741/2906/1742/1739/88/6196/1740/6197/3845/3265/801/5924/4747/5879/5595 35 West_Nile_virus R-HSA-2682334 EPH-Ephrin signaling 38/1715 92/10654 6.379984919695111e-9 3.548025368843104e-8 1.561346520431715e-8 1173/1072/71/2042/2904/5747/1947/4627/7074/1949/5921/2902/2041/102/10094/6714/4637/4067/2043/5063/2534/9475/998/1948/4628/2048/7525/10097/6093/387/60/3265/5058/10109/5062/5663/1969/5879 38 West_Nile_virus R-HSA-202403 TCR signaling 45/1715 119/10654 7.395127656651549e-9 4.0952849796078745e-8 1.8021739667470162e-8 5295/8454/5718/5689/8945/9402/5684/5290/4790/5682/5291/7321/5690/5717/10197/7316/10213/920/5970/5711/5795/5687/23291/5685/55824/5708/5692/5686/5063/5728/1445/5702/5719/7189/6233/7311/3932/5296/7334/5694/5058/5062/5693/5691/7314 45 West_Nile_virus R-HSA-8939211 ESR-mediated signaling 70/1715 223/10654 7.510031073263601e-9 4.141515043749551e-8 1.8225180010430497e-8 5295/3725/2963/3838/596/5434/5440/5590/1839/4893/6464/685/5290/5747/59345/5430/2770/207/5436/5594/2069/3315/5441/5438/5431/2100/5435/5433/1950/865/1655/6714/2099/4609/2962/8850/8503/1387/5437/3320/2033/8243/9126/595/2783/2784/2782/5439/2066/2771/10498/3326/7514/1025/2353/1386/1956/5536/5296/4343/3845/3265/801/8877/5432/3480/2773/2957/5595/2787 70 West_Nile_virus R-HSA-69306 DNA Replication 47/1715 127/10654 7.742200669894626e-9 4.2517585345504654e-8 1.8710318285578682e-8 8454/5718/1017/6118/5689/5684/5682/7321/8697/5690/5717/10197/8881/7316/10213/5422/9978/4174/890/5426/4171/6119/5711/5687/5427/5685/5708/5692/5985/5686/5702/51529/5719/64682/29945/10393/6233/23595/7311/6117/29882/5694/5693/4999/5691/7314/996 47 West_Nile_virus R-HSA-113418 Formation of the Early Elongation Complex 20/1715 33/10654 8.419409195776315e-9 4.566576674910776e-8 2.0095709191564872e-8 2963/5434/5440/902/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/2068/5439/2071/5432/22916/25920 20 West_Nile_virus R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 20/1715 33/10654 8.419409195776315e-9 4.566576674910776e-8 2.0095709191564872e-8 2963/5434/5440/902/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/2068/5439/2071/5432/22916/25920 20 West_Nile_virus R-HSA-389356 CD28 co-stimulation 20/1715 33/10654 8.419409195776315e-9 4.566576674910776e-8 2.0095709191564872e-8 5295/9402/5290/207/6714/8503/4067/5063/2534/998/2885/7525/79109/2475/3932/5296/5058/5062/5879/253260 20 West_Nile_virus R-HSA-2871837 FCERI mediated NF-kB activation 35/1715 82/10654 9.040530763058526e-9 4.8833686662750565e-8 2.1489786240057155e-8 8454/5718/5689/8945/5684/4790/5682/7321/5690/5717/10197/7316/10213/10125/5970/5711/5687/4067/23291/5685/5708/5692/5686/5702/5719/7189/6233/10235/7311/115727/7334/5694/5693/5691/7314 35 West_Nile_virus R-HSA-1234174 Cellular response to hypoxia 33/1715 75/10654 9.551518906593356e-9 5.13832731383267e-8 2.261175904418019e-8 5718/5689/5684/5682/7321/7422/5690/5717/3091/10197/7316/10213/9978/5711/1387/5687/5685/5708/5692/5686/2033/7428/5702/8453/5719/6233/7311/54583/5694/405/5693/5691/7314 33 West_Nile_virus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 23/1715 42/10654 9.751725608553146e-9 5.213374816993194e-8 2.294201361044046e-8 23165/53981/4928/81929/55706/7175/9631/29894/79023/57122/81608/4686/8189/9688/10898/10189/10482/51692/8086/1977/6396/22916/55339 23 West_Nile_virus R-HSA-76009 Platelet Aggregation (Plug Formation) 22/1715 39/10654 9.77013338237723e-9 5.213374816993194e-8 2.294201361044046e-8 6464/5770/5747/207/3674/7094/5908/54518/10125/6850/6714/2244/2335/3690/1445/6654/2885/2266/10235/5906/2243/7450 22 West_Nile_virus R-HSA-6807070 PTEN Regulation 50/1715 140/10654 1.0317018159670872e-8 5.482995941308955e-8 2.412851021213349e-8 5718/5689/3725/5684/5682/2146/207/6045/5690/5594/5717/1460/10197/7316/10213/1457/1108/10014/5711/5687/5685/5708/5692/54815/5686/23512/5728/6615/5702/7157/1107/5719/5371/10542/6233/2475/55004/57504/7311/1386/4343/8726/648/5694/64121/57521/5693/5691/7314/5595 50 West_Nile_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 40/1715 101/10654 1.0876110694516848e-8 5.7569132109932555e-8 2.533391246112358e-8 8454/5718/5689/8945/5684/4790/5682/7321/5690/3553/5532/5717/841/10197/7316/10213/5970/6850/10768/6714/5711/5687/23291/5685/5708/5692/5686/5702/9040/5719/7189/6233/5580/7311/7334/5694/801/5693/5691/7314 40 West_Nile_virus R-HSA-6806834 Signaling by MET 34/1715 79/10654 1.1393136986137937e-8 5.976508077736576e-8 2.6300263164546392e-8 5295/4893/6464/5290/5770/5747/10048/5908/3082/382/3688/7316/6774/4233/6714/1281/3673/5795/2335/64759/6654/200958/6233/2885/7311/5906/57610/23163/3845/2549/3265/5781/7314/5879 34 West_Nile_virus R-HSA-1250342 PI3K events in ERBB4 signaling 10/1715 10/10654 1.1427010892182224e-8 5.976508077736576e-8 2.6300263164546392e-8 5295/1839/685/5290/2069/145957/3084/2066/9542/10718 10 West_Nile_virus R-HSA-8853334 Signaling by FGFR3 fusions in cancer 10/1715 10/10654 1.1427010892182224e-8 5.976508077736576e-8 2.6300263164546392e-8 5295/4893/5290/10818/2261/6654/2885/3845/2549/3265 10 West_Nile_virus R-HSA-210993 Tie2 Signaling 14/1715 18/10654 1.2035349314538395e-8 6.245114329354961e-8 2.7482293710363266e-8 5295/4893/6464/5290/5291/7010/6654/2885/5296/3845/3265/5781/284/9046 14 West_Nile_virus R-HSA-5654221 Phospholipase C-mediated cascade; FGFR2 14/1715 18/10654 1.2035349314538395e-8 6.245114329354961e-8 2.7482293710363266e-8 8823/8074/8817/2254/2263/2249/26281/2248/2247/2255/27006/2246/2251/2252 14 West_Nile_virus R-HSA-438066 Unblocking of NMDA receptors, glutamate binding and activation 16/1715 23/10654 1.5050937792372684e-8 7.748881254041874e-8 3.409978093584436e-8 818/815/2904/817/2902/2905/2903/816/1741/2906/1742/1739/88/1740/801/4747 16 West_Nile_virus R-HSA-9617324 Negative regulation of NMDA receptor-mediated neuronal transmission 16/1715 23/10654 1.5050937792372684e-8 7.748881254041874e-8 3.409978093584436e-8 818/815/2904/817/2902/2905/2903/816/1741/2906/1742/1739/88/1740/801/4747 16 West_Nile_virus R-HSA-1839124 FGFR1 mutant receptor activation 19/1715 31/10654 1.5387494053500907e-8 7.891329635219532e-8 3.472664027638337e-8 5295/8805/11052/5290/9530/8074/2260/2254/6774/2249/6772/26281/2247/2885/2246/2251/9846/11160/7750 19 West_Nile_virus R-HSA-1295596 Spry regulation of FGF signaling 13/1715 16/10654 1.6219651514827794e-8 8.285852983156214e-8 3.646278247519427e-8 5594/7316/673/6714/6233/2885/7311/5518/5781/7314/5595/5515/5516 13 West_Nile_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 32/1715 73/10654 1.786178350034621e-8 9.089509904809384e-8 3.999936073436603e-8 8454/57154/5718/5689/7291/5684/5682/5690/5717/10197/7316/10213/9978/865/6772/2099/5711/5687/2908/5685/5708/5692/5686/55294/5702/5719/6233/7311/5694/5693/5691/7314 32 West_Nile_virus R-HSA-190322 FGFR4 ligand binding and activation 12/1715 14/10654 1.937484867746648e-8 9.821557906500315e-8 4.3220816280502155e-8 8823/8074/8817/2254/152831/2249/26281/2247/9965/2264/2246/2251 12 West_Nile_virus R-HSA-375165 NCAM signaling for neurite out-growth 29/1715 63/10654 2.171757625247576e-8 1.096695996197818e-7 4.826128056105725e-8 5786/2674/9252/4893/6711/6712/5747/5594/2675/4902/2260/4684/2668/57731/6714/6710/1281/64096/2534/6708/6654/2885/6709/51332/9048/3845/5623/3265/5595 29 West_Nile_virus R-HSA-877300 Interferon gamma signaling 37/1715 92/10654 2.3710576281525393e-8 1.1927686846965826e-7 5.248906199726995e-8 3665/818/3460/5777/815/10379/960/5770/4281/7412/3107/817/9021/2209/3383/7706/3662/4684/3663/3664/6772/8651/3659/3459/3717/10612/3458/816/3661/5371/5580/3716/4940/4938/5781/3105/3660 37 West_Nile_virus R-HSA-445144 Signal transduction by L1 15/1715 21/10654 2.461681517690325e-8 1.228975848604488e-7 5.4082396979560173e-8 5604/3674/5594/1460/3678/2260/4684/3688/1457/5605/3690/1956/5058/5879/5595 15 West_Nile_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 15/1715 21/10654 2.461681517690325e-8 1.228975848604488e-7 5.4082396979560173e-8 9252/4893/4790/5970/1387/4067/5063/2534/2033/5894/30835/3845/3265/5058/5062 15 West_Nile_virus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 28/1715 60/10654 2.6159777068024358e-8 1.2913328155676443e-7 5.682648202042744e-8 8454/5718/5689/8945/5684/5682/5690/5717/10197/7316/10213/5970/5711/5687/23291/5685/5708/5692/5686/5702/9040/5719/6233/7311/5694/5693/5691/7314 28 West_Nile_virus R-HSA-5610780 Degradation of GLI1 by the proteasome 28/1715 60/10654 2.6159777068024358e-8 1.2913328155676443e-7 5.682648202042744e-8 8454/5718/5689/8945/5684/5682/5690/5717/10197/7316/10213/9978/8650/5711/5687/5685/5708/5692/5686/5702/83737/5719/6233/7311/5694/5693/5691/7314 28 West_Nile_virus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 28/1715 60/10654 2.6159777068024358e-8 1.2913328155676443e-7 5.682648202042744e-8 8454/5718/5689/8945/5684/5682/1452/5690/5717/10197/2737/7316/10213/9978/5711/5687/5685/5708/5692/5686/5702/5719/6233/7311/5694/5693/5691/7314 28 West_Nile_virus R-HSA-167161 HIV Transcription Initiation 24/1715 47/10654 2.8823557045652474e-8 1.3915548786142843e-7 6.123686112263164e-8 2963/5434/5440/902/2959/5430/5436/5441/5438/5431/5435/5433/6872/2960/8148/2962/5437/83860/2068/5439/2071/2961/5432/2957 24 West_Nile_virus R-HSA-167162 RNA Polymerase II HIV Promoter Escape 24/1715 47/10654 2.8823557045652474e-8 1.3915548786142843e-7 6.123686112263164e-8 2963/5434/5440/902/2959/5430/5436/5441/5438/5431/5435/5433/6872/2960/8148/2962/5437/83860/2068/5439/2071/2961/5432/2957 24 West_Nile_virus R-HSA-73776 RNA Polymerase II Promoter Escape 24/1715 47/10654 2.8823557045652474e-8 1.3915548786142843e-7 6.123686112263164e-8 2963/5434/5440/902/2959/5430/5436/5441/5438/5431/5435/5433/6872/2960/8148/2962/5437/83860/2068/5439/2071/2961/5432/2957 24 West_Nile_virus R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 24/1715 47/10654 2.8823557045652474e-8 1.3915548786142843e-7 6.123686112263164e-8 2963/5434/5440/902/2959/5430/5436/5441/5438/5431/5435/5433/6872/2960/8148/2962/5437/83860/2068/5439/2071/2961/5432/2957 24 West_Nile_virus R-HSA-75953 RNA Polymerase II Transcription Initiation 24/1715 47/10654 2.8823557045652474e-8 1.3915548786142843e-7 6.123686112263164e-8 2963/5434/5440/902/2959/5430/5436/5441/5438/5431/5435/5433/6872/2960/8148/2962/5437/83860/2068/5439/2071/2961/5432/2957 24 West_Nile_virus R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 24/1715 47/10654 2.8823557045652474e-8 1.3915548786142843e-7 6.123686112263164e-8 2963/5434/5440/902/2959/5430/5436/5441/5438/5431/5435/5433/6872/2960/8148/2962/5437/83860/2068/5439/2071/2961/5432/2957 24 West_Nile_virus R-HSA-3371556 Cellular response to heat stress 36/1715 89/10654 3.063883784422097e-8 1.4737951926526728e-7 6.48559341228035e-8 23165/818/6118/4928/815/81929/55706/7175/9631/7531/1915/817/5594/9530/545/79023/57122/3313/9532/9688/6119/1387/3309/3320/2033/6767/816/8086/3326/2475/6117/6396/3312/57521/51182/5595 36 West_Nile_virus R-HSA-442755 Activation of NMDA receptors and postsynaptic events 37/1715 93/10654 3.334197730366045e-8 1.594016575329628e-7 7.014640468066647e-8 5923/818/815/3838/8573/4893/2904/817/5594/114/10381/5573/2902/6714/55327/2905/27330/2903/3084/6195/816/2066/1741/2906/1742/1739/88/6196/1740/6197/3845/3265/801/5924/4747/5879/5595 37 West_Nile_virus R-HSA-68949 Orc1 removal from chromatin 31/1715 71/10654 3.3380013261834394e-8 1.594016575329628e-7 7.014640468066647e-8 8454/5718/1017/5689/5684/5682/5690/5717/10197/7316/10213/9978/4174/890/4171/5711/5687/5685/5708/5692/5686/5702/5719/6233/23595/7311/5694/5693/4999/5691/7314 31 West_Nile_virus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 26/1715 54/10654 3.6767336074515714e-8 1.749434980007643e-7 7.698575784555637e-8 8454/5718/5689/5684/5682/5690/5717/10197/7316/10213/9978/6790/5711/5687/5685/5708/5692/5686/5702/5719/6233/7311/5694/5693/5691/7314 26 West_Nile_virus R-HSA-69615 G1/S DNA Damage Checkpoints 30/1715 68/10654 4.1580333799337524e-8 1.9713266168175129e-7 8.675033670365383e-8 5718/1017/5689/5684/5682/1029/5690/5717/10197/7316/10213/890/1026/5711/5687/5685/5708/5692/5686/1111/5702/7157/5719/6233/7311/5694/5693/5691/7314/4193 30 West_Nile_virus R-HSA-68886 M Phase 105/1715 395/10654 4.3841699044538e-8 2.0710881484122253e-7 9.114044962663815e-8 4000/115106/5718/23165/5689/5905/4928/26271/81929/5684/55706/7175/55143/5579/5682/9631/5525/7531/10142/1783/7321/5526/7532/5862/8697/5690/5578/9212/5594/5717/5861/121441/1460/79023/9133/10381/57122/64105/5116/10197/6232/332/7443/8881/5528/7316/10213/5501/26003/1457/983/8548/9688/9702/5519/5711/5687/5685/7444/5708/3320/5692/5686/8243/9126/10426/5529/9918/5702/10540/51529/8086/2010/5719/4001/64682/29945/10393/79648/4751/11004/23592/6233/5527/7514/7311/9184/5518/5347/113130/29882/6396/5694/25909/27229/7112/5693/140735/10806/5691/7314/996/5595/5515/5516 105 West_Nile_virus R-HSA-202424 Downstream TCR signaling 38/1715 98/10654 4.9412516605234705e-8 2.3259177459178338e-7 1.023544986822719e-7 5295/8454/5718/5689/8945/5684/5290/4790/5682/5291/7321/5690/5717/10197/7316/10213/920/5970/5711/5687/23291/5685/5708/5692/5686/5728/5702/5719/7189/6233/7311/3932/5296/7334/5694/5693/5691/7314 38 West_Nile_virus R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 17/1715 27/10654 5.0570953233085645e-8 2.3635644099718752e-7 1.0401118040847402e-7 2963/5434/5440/902/5430/5436/5441/5438/5431/5435/5433/2962/5437/2068/5439/2071/5432 17 West_Nile_virus R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 17/1715 27/10654 5.0570953233085645e-8 2.3635644099718752e-7 1.0401118040847402e-7 2963/5434/5440/902/5430/5436/5441/5438/5431/5435/5433/2962/5437/2068/5439/2071/5432 17 West_Nile_virus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 29/1715 65/10654 5.149318824830488e-8 2.3981633254864253e-7 1.0553374269970613e-7 3725/2963/6917/5434/5440/902/5430/5436/4292/545/5441/5438/5431/5435/5433/2962/5437/2068/5439/1111/2071/7157/672/1025/2353/1386/11198/5432/25920 29 West_Nile_virus R-HSA-180292 GAB1 signalosome 13/1715 17/10654 5.872071604826593e-8 2.7155755702320877e-7 1.195018080982254e-7 5295/1839/685/5290/2069/1950/6714/55824/1445/2885/1956/2549/5781 13 West_Nile_virus R-HSA-9034015 Signaling by NTRK3 (TRKC) 13/1715 17/10654 5.872071604826593e-8 2.7155755702320877e-7 1.195018080982254e-7 5295/4908/4893/6464/5290/3667/6714/6654/2885/3845/3265/4916/25920 13 West_Nile_virus R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 26/1715 55/10654 5.912164728737113e-8 2.724557032334096e-7 1.1989704694641698e-7 8454/5718/5689/8945/26271/5684/5682/5690/5717/10197/7316/10213/5711/5687/5685/5708/5692/5686/5702/5719/6233/7311/5694/5693/5691/7314 26 West_Nile_virus R-HSA-180534 Vpu mediated degradation of CD4 25/1715 52/10654 6.98114173167215e-8 3.1948419452582966e-7 1.4059243765173078e-7 5718/5689/8945/5684/5682/5690/5717/10197/7316/10213/920/5711/5687/5685/5708/5692/5686/5702/5719/6233/7311/5694/5693/5691/7314 25 West_Nile_virus R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 25/1715 52/10654 6.98114173167215e-8 3.1948419452582966e-7 1.4059243765173078e-7 5718/5689/1019/5684/5682/5690/5717/10197/7316/10213/5711/5687/5685/5708/5692/5686/595/5702/5719/6233/7311/5694/5693/5691/7314 25 West_Nile_virus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 27/1715 59/10654 7.733151323443622e-8 3.5136450019108985e-7 1.5462170721610938e-7 8454/5718/5689/8945/5684/5682/5690/5717/10197/7316/10213/5711/5687/23291/5685/5708/5692/5686/5702/9040/5719/6233/7311/5694/5693/5691/7314 27 West_Nile_virus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 29/1715 66/10654 7.784403190879989e-8 3.5136450019108985e-7 1.5462170721610938e-7 5718/5689/5684/5682/7321/5690/5717/3091/10197/7316/10213/9978/5711/5687/5685/5708/5692/5686/7428/5702/8453/5719/6233/7311/54583/5694/5693/5691/7314 29 West_Nile_virus R-HSA-69563 p53-Dependent G1 DNA Damage Response 29/1715 66/10654 7.784403190879989e-8 3.5136450019108985e-7 1.5462170721610938e-7 5718/1017/5689/5684/5682/1029/5690/5717/10197/7316/10213/890/1026/5711/5687/5685/5708/5692/5686/5702/7157/5719/6233/7311/5694/5693/5691/7314/4193 29 West_Nile_virus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 29/1715 66/10654 7.784403190879989e-8 3.5136450019108985e-7 1.5462170721610938e-7 5718/1017/5689/5684/5682/1029/5690/5717/10197/7316/10213/890/1026/5711/5687/5685/5708/5692/5686/5702/7157/5719/6233/7311/5694/5693/5691/7314/4193 29 West_Nile_virus R-HSA-177929 Signaling by EGFR 24/1715 49/10654 8.128402372558889e-8 3.656393968270517e-7 1.609035281939985e-7 5295/1839/4893/6464/685/5290/2069/7316/1950/102/6714/55824/1445/998/6654/6233/2885/7311/1956/3845/2549/3265/5781/7314 24 West_Nile_virus R-HSA-5654228 Phospholipase C-mediated cascade; FGFR4 12/1715 15/10654 8.259168975715267e-8 3.69002871525177e-7 1.623836612174527e-7 8823/8074/8817/2254/152831/2249/26281/2247/9965/2264/2246/2251 12 West_Nile_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 12/1715 15/10654 8.259168975715267e-8 3.69002871525177e-7 1.623836612174527e-7 54106/3665/4615/7316/3654/7189/6233/51135/7311/7334/51284/7314 12 West_Nile_virus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 32/1715 77/10654 8.355492573291336e-8 3.720452436350669e-7 1.637224896117897e-7 5718/5689/5684/5682/63943/5690/5717/9133/10381/10197/7316/10213/983/1026/5711/5687/5685/5708/3320/5692/5686/5702/7157/5719/6233/3326/7311/5347/5694/5693/5691/7314 32 West_Nile_virus R-HSA-167169 HIV Transcription Elongation 23/1715 46/10654 9.307047144371732e-8 4.1025712830374393e-7 1.8053803825202693e-7 2963/6917/5434/5440/902/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/2068/5439/2071/1025/11198/5432/22916/25920 23 West_Nile_virus R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 23/1715 46/10654 9.307047144371732e-8 4.1025712830374393e-7 1.8053803825202693e-7 2963/6917/5434/5440/902/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/2068/5439/2071/1025/11198/5432/22916/25920 23 West_Nile_virus R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 23/1715 46/10654 9.307047144371732e-8 4.1025712830374393e-7 1.8053803825202693e-7 2963/6917/5434/5440/902/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/2068/5439/2071/1025/11198/5432/22916/25920 23 West_Nile_virus R-HSA-5632684 Hedgehog 'on' state 34/1715 85/10654 1.0213832535888628e-7 4.472369196777811e-7 1.968113910569902e-7 57154/5718/5689/5684/5682/1452/5690/5717/409/79577/10197/8452/2737/7316/10213/9978/8650/5711/5687/5685/5708/5692/5686/408/5702/83737/5719/6233/7311/6469/5694/5693/5691/7314 34 West_Nile_virus R-HSA-69002 DNA Replication Pre-Initiation 34/1715 85/10654 1.0213832535888628e-7 4.472369196777811e-7 1.968113910569902e-7 5718/1017/6118/5689/5684/5682/5690/5717/10197/7316/10213/5422/4174/5426/4171/6119/5711/5687/5427/5685/5708/5692/5686/5702/5719/6233/23595/7311/6117/5694/5693/4999/5691/7314 34 West_Nile_virus R-HSA-5655291 Signaling by FGFR4 in disease 10/1715 11/10654 1.0739286054007485e-7 4.6868804699277704e-7 2.0625118911670008e-7 5295/4893/5290/10818/2264/6654/2885/3845/2549/3265 10 West_Nile_virus R-HSA-167044 Signalling to RAS 14/1715 20/10654 1.1047425715602811e-7 4.789640491172534e-7 2.107732537845273e-7 4893/6464/5899/6714/5898/4914/53358/5603/6654/2885/5900/3845/3265/25759 14 West_Nile_virus R-HSA-190241 FGFR2 ligand binding and activation 14/1715 20/10654 1.1047425715602811e-7 4.789640491172534e-7 2.107732537845273e-7 8823/8074/8817/2254/2263/2249/26281/2248/2247/2255/27006/2246/2251/2252 14 West_Nile_virus R-HSA-1169091 Activation of NF-kappaB in B cells 29/1715 67/10654 1.1632345219973852e-7 5.026698688500176e-7 2.212052533634372e-7 8454/5718/5689/8945/5684/4790/5579/5682/5690/5717/10197/7316/10213/5970/5711/5687/23291/5685/5708/5692/5686/5702/5719/6233/7311/5694/5693/5691/7314 29 West_Nile_virus R-HSA-5610783 Degradation of GLI2 by the proteasome 27/1715 60/10654 1.1919929737059146e-7 5.134139671060116e-7 2.2593330874164394e-7 8454/5718/5689/8945/5684/5682/1452/5690/5717/10197/7316/10213/9978/5711/5687/5685/5708/5692/5686/5702/5719/6233/7311/5694/5693/5691/7314 27 West_Nile_virus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 18/1715 31/10654 1.2041960652047156e-7 5.169805908598747e-7 2.2750283968036976e-7 3725/5601/9252/5594/5528/5519/5602/6195/2353/6196/5518/1386/6197/5599/51231/5595/5515/5516 18 West_Nile_virus R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 24/1715 50/10654 1.325940601554411e-7 5.673992574184134e-7 2.4969011327972675e-7 5718/5689/5684/5682/5690/5717/10197/7316/10213/5711/5687/5685/5708/5692/5686/5702/5719/6233/7311/5694/5062/5693/5691/7314 24 West_Nile_virus R-HSA-447115 Interleukin-12 family signaling 26/1715 57/10654 1.458912266009241e-7 6.20273021483929e-7 2.72957778801729e-7 1072/6627/6775/821/5908/9987/4478/3313/3185/6774/3936/6772/6647/5898/3717/3458/3181/998/4001/3716/6845/375/7297/5062/3586/3572 26 West_Nile_virus R-HSA-69541 Stabilization of p53 26/1715 57/10654 1.458912266009241e-7 6.20273021483929e-7 2.72957778801729e-7 5718/5689/5684/5682/1029/5690/5717/10197/7316/10213/5711/5687/5685/5708/5692/5686/5702/7157/5719/6233/7311/5694/5693/5691/7314/4193 26 West_Nile_virus R-HSA-977606 Regulation of Complement cascade 23/1715 47/10654 1.5464043107519632e-7 6.553571966466519e-7 2.883969454135494e-7 727/629/722/1378/1604/717/731/712/710/716/715/3426/721/975/725/732/713/720/4179/714/729/5627/718 23 West_Nile_virus R-HSA-983169 Class I MHC mediated antigen processing & presentation 98/1715 371/10654 1.7291407345021835e-7 7.304511179723967e-7 3.214428288497649e-7 8454/57154/5718/8773/5689/8945/5684/8065/64410/10952/5682/7319/26046/3107/7321/9021/8697/5690/7174/5717/821/811/10533/2209/10197/7099/4615/9690/9554/8881/8452/23376/7316/10213/9978/29927/7317/54926/4008/8651/5711/23327/10134/9341/5687/26270/51465/23291/5685/929/3309/5708/5692/5686/89910/55521/25898/55294/7328/7428/5702/8453/83737/51529/9040/695/63891/5719/10075/64682/29945/9246/10393/80176/9902/6233/56658/4012/7311/6047/9320/29882/6396/7334/92591/5930/5694/7097/84961/8673/29116/3105/5693/51676/5691/9820/7314/996 98 West_Nile_virus R-HSA-180585 Vif-mediated degradation of APOBEC3G 25/1715 54/10654 1.7697780877052952e-7 7.452292394874054e-7 3.279460993191921e-7 5718/5689/5684/8065/5682/5690/5717/10197/7316/10213/9978/5711/5687/5685/5708/5692/5686/5702/5719/6233/7311/5694/5693/5691/7314 25 West_Nile_virus R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 13/1715 18/10654 1.8010266955595817e-7 7.559723518304231e-7 3.326737208358463e-7 1839/4893/5578/5594/6195/6654/2885/6196/1956/6197/3845/3265/5595 13 West_Nile_virus R-HSA-69202 Cyclin E associated events during G1/S transition 33/1715 83/10654 1.8600367742449294e-7 7.782630058586721e-7 3.424829616070029e-7 8454/5718/1017/5689/1019/5684/902/5682/207/5690/5717/10197/286826/7316/10213/890/1026/4609/5711/5687/5685/5708/5692/5686/595/5702/5719/6233/7311/5694/5693/5691/7314 33 West_Nile_virus R-HSA-186763 Downstream signal transduction 17/1715 29/10654 2.2478367021556812e-7 9.375470802029075e-7 4.1257762254756176e-7 5295/4893/5290/5291/5921/6774/6772/6714/5159/6654/2885/5155/5296/3845/3265/5781/5156 17 West_Nile_virus R-HSA-69275 G2/M Transition 60/1715 196/10654 2.3653665022740444e-7 9.83455220819303e-7 4.327799909523488e-7 8454/115106/5718/1017/5689/8945/5684/902/5682/7531/10142/7532/63943/5690/5717/121441/9133/10381/5116/10197/286826/7316/10213/9978/890/983/1026/6790/9702/5519/5711/5687/23291/5685/5708/3320/5692/5686/2033/10426/5702/10540/7157/5719/4751/6233/3326/7514/7311/5518/5347/5694/27229/5693/10806/5691/5500/7314/5515/5516 60 West_Nile_virus R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 23/1715 48/10654 2.5192758459791964e-7 1.044152693396409e-6 4.5949056310312385e-7 2963/6917/5434/5440/902/5430/5436/5441/5438/5431/5435/4686/5433/2962/5437/2068/5439/2071/1025/11198/5432/22916/25920 23 West_Nile_virus R-HSA-193639 p75NTR signals via NF-kB 12/1715 16/10654 2.8170780448412616e-7 1.1639212736993049e-6 5.121960081529566e-7 4804/4790/5584/8878/4615/7316/5970/3654/7189/6233/7311/7314 12 West_Nile_virus R-HSA-167172 Transcription of the HIV genome 30/1715 73/10654 2.8354856682395575e-7 1.1678656596061678e-6 5.139317773684199e-7 2963/6917/5434/5440/902/2959/5430/5436/5441/5438/5431/5435/4686/5433/6872/2960/8148/2962/5437/83860/2068/5439/2071/1025/11198/2961/5432/22916/2957/25920 30 West_Nile_virus R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 24/1715 52/10654 3.3473060441134567e-7 1.3616510389325728e-6 5.992091066622854e-7 5718/5689/5684/5682/5690/5717/10197/7316/10213/5711/5687/5685/5708/5692/5686/5702/7157/5719/6233/7311/5694/5693/5691/7314 24 West_Nile_virus R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 24/1715 52/10654 3.3473060441134567e-7 1.3616510389325728e-6 5.992091066622854e-7 5718/5689/5684/5682/5690/5717/10197/7316/10213/5711/5687/5685/5708/5692/5686/1111/5702/5719/6233/7311/5694/5693/5691/7314 24 West_Nile_virus R-HSA-69610 p53-Independent DNA Damage Response 24/1715 52/10654 3.3473060441134567e-7 1.3616510389325728e-6 5.992091066622854e-7 5718/5689/5684/5682/5690/5717/10197/7316/10213/5711/5687/5685/5708/5692/5686/1111/5702/5719/6233/7311/5694/5693/5691/7314 24 West_Nile_virus R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 24/1715 52/10654 3.3473060441134567e-7 1.3616510389325728e-6 5.992091066622854e-7 5718/5689/5684/5682/5690/5717/10197/7316/10213/5711/5687/5685/5708/5692/5686/1111/5702/5719/6233/7311/5694/5693/5691/7314 24 West_Nile_virus R-HSA-453274 Mitotic G2-G2/M phases 60/1715 198/10654 3.4935170019288943e-7 1.4167555103207022e-6 6.234584188057718e-7 8454/115106/5718/1017/5689/8945/5684/902/5682/7531/10142/7532/63943/5690/5717/121441/9133/10381/5116/10197/286826/7316/10213/9978/890/983/1026/6790/9702/5519/5711/5687/23291/5685/5708/3320/5692/5686/2033/10426/5702/10540/7157/5719/4751/6233/3326/7514/7311/5518/5347/5694/27229/5693/10806/5691/5500/7314/5515/5516 60 West_Nile_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 33/1715 85/10654 3.5943629640622806e-7 1.453181100194505e-6 6.39487889311694e-7 8454/5718/1017/5689/1019/5684/902/5682/207/5690/5717/10197/286826/7316/10213/890/1026/4609/5711/5687/5685/5708/5692/5686/595/5702/5719/6233/7311/5694/5693/5691/7314 33 West_Nile_virus R-HSA-5687128 MAPK6/MAPK4 signaling 34/1715 89/10654 3.765098130107414e-7 1.5175533136029272e-6 6.678155704777677e-7 5718/5689/3725/5684/5682/5690/5717/3315/10197/7316/10213/983/4609/5711/5687/5685/5708/5692/5686/5063/5702/998/5719/6233/7514/7311/4343/5694/5058/5062/5693/5691/7314/5879 34 West_Nile_virus R-HSA-180336 SHC1 events in EGFR signaling 11/1715 14/10654 4.1410911457409893e-7 1.655127698301452e-6 7.283566502388788e-7 1839/4893/6464/685/2069/1950/6654/2885/1956/3845/3265 11 West_Nile_virus R-HSA-877312 Regulation of IFNG signaling 11/1715 14/10654 4.1410911457409893e-7 1.655127698301452e-6 7.283566502388788e-7 3460/5777/5770/9021/6772/8651/3459/3717/3458/3716/5781 11 West_Nile_virus R-HSA-6804757 Regulation of TP53 Degradation 19/1715 36/10654 4.14409818239362e-7 1.655127698301452e-6 7.283566502388788e-7 1017/1029/207/7316/890/983/5519/7157/6233/5527/79109/2475/7311/5518/7314/253260/4193/5515/5516 19 West_Nile_virus R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 25/1715 56/10654 4.2165703639166986e-7 1.6789848156018758e-6 7.388552299310227e-7 5718/5689/5684/5682/5690/5717/10197/84447/7316/10213/5711/5687/5685/5708/5692/5686/5702/5719/6233/7311/6469/5694/5693/5691/7314 25 West_Nile_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 24/1715 53/10654 5.190051298060422e-7 2.0542004837368275e-6 9.039728987612747e-7 596/10018/7531/1029/842/55075/7532/207/10971/5594/7533/2810/841/7534/6774/54205/598/836/7157/840/5599/140735/7529/5595 24 West_Nile_virus R-HSA-169911 Regulation of Apoptosis 24/1715 53/10654 5.190051298060422e-7 2.0542004837368275e-6 9.039728987612747e-7 5718/5689/5684/5682/5690/5717/10197/7316/10213/5711/5687/5685/5708/5692/5686/5702/5719/6233/7311/5694/5062/5693/5691/7314 24 West_Nile_virus R-HSA-110056 MAPK3 (ERK1) activation 9/1715 10/10654 6.101729098676619e-7 2.4078080694777795e-6 1.0595816997701914e-6 5604/983/3717/3716/7297/5781/3569/3572/5595 9 West_Nile_virus R-HSA-4641258 Degradation of DVL 25/1715 57/10654 6.370990752906932e-7 2.5065569589048766e-6 1.1030372049809016e-6 5718/5689/5684/5682/5690/5717/10197/8452/7316/10213/9978/5711/5687/5685/5708/5692/5686/5702/5719/6233/7311/5694/5693/5691/7314 25 West_Nile_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 19/1715 37/10654 7.237131897610194e-7 2.838851143169713e-6 1.2492668156589025e-6 1017/1029/207/7316/890/983/5519/7157/6233/5527/79109/2475/7311/5518/7314/253260/4193/5515/5516 19 West_Nile_virus R-HSA-5678895 Defective CFTR causes cystic fibrosis 26/1715 61/10654 7.520548895942201e-7 2.941271051884813e-6 1.2943377921799635e-6 5718/5689/5684/5682/5690/91445/5717/1080/10197/7316/10213/5711/5687/5685/5708/5692/5686/5702/5719/6233/7311/11160/5694/5693/5691/7314 26 West_Nile_virus R-HSA-9020591 Interleukin-12 signaling 22/1715 47/10654 7.641648477411815e-7 2.9797907376416486e-6 1.3112887919819091e-6 1072/6627/6775/5908/9987/4478/3313/3185/3936/6647/5898/3717/3458/3181/998/4001/3716/6845/375/7297/5062/3586 22 West_Nile_virus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 15/1715 25/10654 7.774452087995023e-7 3.0137434858757174e-6 1.326230062069739e-6 7321/8697/8881/7316/51529/64682/29945/10393/4751/6233/7311/9184/29882/7314/996 15 West_Nile_virus R-HSA-9006335 Signaling by Erythropoietin 15/1715 25/10654 7.774452087995023e-7 3.0137434858757174e-6 1.326230062069739e-6 5295/4893/6464/5290/5291/4067/3717/5294/6654/2885/8660/5293/3845/2549/3265 15 West_Nile_virus R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 18/1715 34/10654 7.897541140748543e-7 3.0435553285106958e-6 1.3393490823491684e-6 2963/6917/5434/5440/5430/5436/5441/5438/5431/5435/5433/2962/5437/5439/1025/11198/5432/25920 18 West_Nile_virus R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 18/1715 34/10654 7.897541140748543e-7 3.0435553285106958e-6 1.3393490823491684e-6 2963/6917/5434/5440/5430/5436/5441/5438/5431/5435/5433/2962/5437/5439/1025/11198/5432/25920 18 West_Nile_virus R-HSA-196299 Beta-catenin phosphorylation cascade 12/1715 17/10654 8.168768167301912e-7 3.1389027534996853e-6 1.3813077367449298e-6 1499/5525/5526/10023/1452/5528/5519/5529/5527/5518/5515/5516 12 West_Nile_virus R-HSA-674695 RNA Polymerase II Pre-transcription Events 32/1715 84/10654 8.869119754598995e-7 3.3981104176050802e-6 1.4953748423451794e-6 2963/6917/5434/5440/902/2959/5430/5436/79577/5441/5438/5431/5435/4686/5433/6872/2960/8148/2962/54623/5437/83860/2068/5439/2071/1025/11198/2961/5432/22916/2957/25920 32 West_Nile_virus R-HSA-4086400 PCP/CE pathway 34/1715 92/10654 9.317578454173608e-7 3.55958504423212e-6 1.5664334792523747e-6 57154/5718/5689/1173/5684/5579/5682/5690/5578/5717/409/10197/7316/10213/5711/5687/4919/5685/5708/5692/5686/5702/5719/23513/57216/6233/7311/387/5694/5693/5691/4920/7314/5879 34 West_Nile_virus R-HSA-3858494 Beta-catenin independent WNT signaling 47/1715 146/10654 9.732406632480926e-7 3.707315590060653e-6 1.6314438863696351e-6 57154/5718/5689/1173/815/5684/5579/5682/5331/1499/59345/5690/5578/5532/5717/409/10197/7316/10213/5711/5687/4919/23236/5685/5708/5692/5686/2783/2784/2782/5702/5719/23513/57216/6233/7311/387/4343/3845/5694/801/5693/5691/4920/7314/5879/2787 47 West_Nile_virus R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 11/1715 15/10654 1.325782032820694e-6 4.964149770618394e-6 2.1845272131704615e-6 1499/5525/5526/1452/5528/5519/5529/5527/5518/5515/5516 11 West_Nile_virus R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 11/1715 15/10654 1.325782032820694e-6 4.964149770618394e-6 2.1845272131704615e-6 1499/5525/5526/1452/5528/5519/5529/5527/5518/5515/5516 11 West_Nile_virus R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 11/1715 15/10654 1.325782032820694e-6 4.964149770618394e-6 2.1845272131704615e-6 1499/5525/5526/1452/5528/5519/5529/5527/5518/5515/5516 11 West_Nile_virus R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 11/1715 15/10654 1.325782032820694e-6 4.964149770618394e-6 2.1845272131704615e-6 1499/5525/5526/1452/5528/5519/5529/5527/5518/5515/5516 11 West_Nile_virus R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 11/1715 15/10654 1.325782032820694e-6 4.964149770618394e-6 2.1845272131704615e-6 1499/5525/5526/1452/5528/5519/5529/5527/5518/5515/5516 11 West_Nile_virus R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 11/1715 15/10654 1.325782032820694e-6 4.964149770618394e-6 2.1845272131704615e-6 1499/5525/5526/1452/5528/5519/5529/5527/5518/5515/5516 11 West_Nile_virus R-HSA-5387390 Hh mutants abrogate ligand secretion 25/1715 59/10654 1.3983459147001777e-6 5.206270947951509e-6 2.291075227474868e-6 5718/5689/5684/5682/5690/5717/10197/84447/7316/10213/5711/5687/5685/5708/5692/5686/5702/5719/6233/7311/6469/5694/5693/5691/7314 25 West_Nile_virus R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 25/1715 59/10654 1.3983459147001777e-6 5.206270947951509e-6 2.291075227474868e-6 5718/5689/5684/5682/5690/5717/10197/7316/10213/5711/5687/5685/5708/5692/5686/5702/5719/6233/23595/7311/5694/5693/4999/5691/7314 25 West_Nile_virus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 14/1715 23/10654 1.4383234576184445e-6 5.340029062369324e-6 2.349936916672388e-6 7321/8697/8881/7316/983/51529/64682/29945/10393/6233/7311/29882/7314/996 14 West_Nile_virus R-HSA-2980766 Nuclear Envelope Breakdown 23/1715 52/10654 1.4893869390653861e-6 5.514078611483649e-6 2.4265292827469773e-6 4000/23165/4928/81929/55706/7175/5579/9631/5578/79023/9133/57122/7443/983/9688/7444/8086/2010/4001/23592/5347/6396/7112 23 West_Nile_virus R-HSA-179812 GRB2 events in EGFR signaling 10/1715 13/10654 2.0396139072249284e-6 7.446568226377993e-6 3.276942011607918e-6 1839/4893/685/2069/1950/6654/2885/1956/3845/3265 10 West_Nile_virus R-HSA-190375 FGFR2c ligand binding and activation 10/1715 13/10654 2.0396139072249284e-6 7.446568226377993e-6 3.276942011607918e-6 8823/8074/8817/2254/2263/2249/26281/2247/2246/2251 10 West_Nile_virus R-HSA-209543 p75NTR recruits signalling complexes 10/1715 13/10654 2.0396139072249284e-6 7.446568226377993e-6 3.276942011607918e-6 4804/5584/8878/4615/7316/3654/7189/6233/7311/7314 10 West_Nile_virus R-HSA-209560 NF-kB is activated and signals survival 10/1715 13/10654 2.0396139072249284e-6 7.446568226377993e-6 3.276942011607918e-6 4804/4790/8878/7316/5970/3654/7189/6233/7311/7314 10 West_Nile_virus R-HSA-5658623 FGFRL1 modulation of FGFR1 signaling 10/1715 13/10654 2.0396139072249284e-6 7.446568226377993e-6 3.276942011607918e-6 8074/8817/2249/2248/2247/2255/27006/53834/200734/161742 10 West_Nile_virus R-HSA-382556 ABC-family proteins mediated transport 36/1715 103/10654 2.1063762702677805e-6 7.669071613847887e-6 3.374857007611361e-6 5718/5689/5684/1965/5682/5243/5690/91445/5717/1080/23/10197/1244/7316/10213/340273/5711/5825/5687/5685/8894/5708/5692/5686/5702/5719/6233/7311/11160/5694/4363/10057/5693/5691/7314/1968 36 West_Nile_virus R-HSA-4608870 Asymmetric localization of PCP proteins 26/1715 64/10654 2.266581726587448e-6 8.229627315818888e-6 3.621535541103911e-6 57154/5718/5689/5684/5682/5690/5717/10197/7316/10213/5711/5687/5685/5708/5692/5686/5702/5719/23513/57216/6233/7311/5694/5693/5691/7314 26 West_Nile_virus R-HSA-167287 HIV elongation arrest and recovery 18/1715 36/10654 2.349697501690732e-6 8.484661115694204e-6 3.7337658930976015e-6 2963/6917/5434/5440/5430/5436/5441/5438/5431/5435/5433/2962/5437/5439/1025/11198/5432/25920 18 West_Nile_virus R-HSA-167290 Pausing and recovery of HIV elongation 18/1715 36/10654 2.349697501690732e-6 8.484661115694204e-6 3.7337658930976015e-6 2963/6917/5434/5440/5430/5436/5441/5438/5431/5435/5433/2962/5437/5439/1025/11198/5432/25920 18 West_Nile_virus R-HSA-69481 G2/M Checkpoints 51/1715 168/10654 2.4582362542516345e-6 8.852337112305066e-6 3.895565648814066e-6 5718/1017/6118/5689/5684/5682/7531/7486/7532/10971/5690/5717/7533/2810/545/9133/10197/7534/580/7316/10213/4174/983/4171/6119/5711/4683/5687/5685/5708/5692/5985/5686/1111/5702/7157/5719/6233/672/7158/23595/7311/6117/7334/5694/5810/5693/4999/5691/7529/7314 51 West_Nile_virus R-HSA-68867 Assembly of the pre-replicative complex 27/1715 68/10654 2.464974923592157e-6 8.852416755570744e-6 3.895600696685153e-6 5718/5689/5684/5682/5690/5717/10197/7316/10213/4174/4171/5711/5687/5685/5708/5692/5686/5702/5719/6233/23595/7311/5694/5693/4999/5691/7314 27 West_Nile_virus R-HSA-5218921 VEGFR2 mediated cell proliferation 13/1715 21/10654 2.6477079582277184e-6 9.48282361126123e-6 4.173017977641512e-6 5590/4893/5579/7422/5578/5921/10768/6714/5580/3845/3265/801/8877 13 West_Nile_virus R-HSA-1059683 Interleukin-6 signaling 9/1715 11/10654 2.8726831318418003e-6 1.0242196478894264e-5 4.5071881318351085e-6 9021/6774/6772/3717/3716/7297/5781/3569/3572 9 West_Nile_virus R-HSA-2424491 DAP12 signaling 16/1715 30/10654 2.875275187549983e-6 1.0242196478894264e-5 4.5071881318351085e-6 5295/9402/4893/6464/5290/5291/6850/2534/695/6654/2885/3932/5296/3845/3265/5879 16 West_Nile_virus R-HSA-112382 Formation of RNA Pol II elongation complex 25/1715 61/10654 2.9238076924708633e-6 1.0359082093216662e-5 4.558624896863174e-6 2963/6917/5434/5440/902/5430/5436/79577/5441/5438/5431/5435/4686/5433/2962/54623/5437/2068/5439/2071/1025/11198/5432/22916/25920 25 West_Nile_virus R-HSA-75955 RNA Polymerase II Transcription Elongation 25/1715 61/10654 2.9238076924708633e-6 1.0359082093216662e-5 4.558624896863174e-6 2963/6917/5434/5440/902/5430/5436/79577/5441/5438/5431/5435/4686/5433/2962/54623/5437/2068/5439/2071/1025/11198/5432/22916/25920 25 West_Nile_virus R-HSA-5610787 Hedgehog 'off' state 38/1715 113/10654 3.242630475870836e-6 1.1457873906696414e-5 5.042159989289772e-6 8454/5718/5689/8945/5684/5682/1452/5690/79809/5717/112/114/10381/7289/10197/5573/2737/7316/10213/9978/2778/8650/5711/5687/5685/5708/5692/5686/5702/83737/5719/6233/7311/115/5694/5693/5691/7314 38 West_Nile_virus R-HSA-8948751 Regulation of PTEN stability and activity 27/1715 69/10654 3.4346949714968496e-6 1.2104085487788362e-5 5.32653230873843e-6 5718/5689/5684/5682/207/5690/5717/1460/10197/7316/10213/1457/5711/5687/5685/5708/5692/5686/5728/5702/5719/6233/7311/5694/5693/5691/7314 27 West_Nile_virus R-HSA-1433559 Regulation of KIT signaling 11/1715 16/10654 3.62274533516114e-6 1.2631688761223235e-5 5.558709773527675e-6 5777/3815/5578/6714/8651/4067/2534/6654/2885/7525/3932 11 West_Nile_virus R-HSA-190242 FGFR1 ligand binding and activation 11/1715 16/10654 3.62274533516114e-6 1.2631688761223235e-5 5.558709773527675e-6 8074/2260/2254/2249/26281/2248/2247/2255/27006/2246/2251 11 West_Nile_virus R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 11/1715 16/10654 3.62274533516114e-6 1.2631688761223235e-5 5.558709773527675e-6 5295/6464/5290/5291/6850/4067/2534/6654/2885/9846/5296 11 West_Nile_virus R-HSA-5654219 Phospholipase C-mediated cascade: FGFR1 11/1715 16/10654 3.62274533516114e-6 1.2631688761223235e-5 5.558709773527675e-6 8074/2260/2254/2249/26281/2248/2247/2255/27006/2246/2251 11 West_Nile_virus R-HSA-195258 RHO GTPase Effectors 84/1715 327/10654 4.4063693319838555e-6 1.5323469075342275e-5 6.743256497495082e-6 85415/3831/5905/4928/81929/5590/1072/27035/71/55143/5579/1495/1499/5525/7531/5747/1783/5526/4627/7532/10971/10458/4771/5578/9212/5594/1080/7533/2810/79023/10381/57122/64105/6232/7534/332/5528/3688/5501/10094/6279/6714/5519/4637/10163/999/55845/5063/9475/3895/5529/998/4628/695/10788/11004/1742/5527/2885/5580/10097/23191/7514/6093/9184/8826/5518/5347/387/60/5300/6396/25909/5058/801/10109/5062/140735/5500/7529/5879/5595/5515/5516 84 West_Nile_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 17/1715 34/10654 4.49424243996052e-6 1.558792509438938e-5 6.859633197834477e-6 7321/29110/57506/9636/7706/7316/23586/64135/83737/3661/9246/6233/7311/5094/5300/1540/7314 17 West_Nile_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 23/1715 55/10654 4.818143041578705e-6 1.6623854787436474e-5 7.315505141664002e-6 834/596/351/4790/842/835/841/7316/5970/24145/837/598/3656/5603/83737/3654/7189/6233/3326/7311/7334/1540/7314 23 West_Nile_virus R-HSA-4641257 Degradation of AXIN 23/1715 55/10654 4.818143041578705e-6 1.6623854787436474e-5 7.315505141664002e-6 5718/5689/5684/5682/5690/5717/10197/7316/10213/5711/5687/5685/5708/5692/5686/5702/5719/6233/7311/5694/5693/5691/7314 23 West_Nile_virus R-HSA-8854691 Interleukin-20 family signaling 14/1715 25/10654 5.6933187977656234e-6 1.9592151894138622e-5 8.621736038391805e-6 6775/11009/6774/3718/6772/3717/163702/3716/282618/53832/3588/6773/7297/5781 14 West_Nile_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 25/1715 63/10654 5.8482566056510876e-006 2.0072922412104513e-5 8.83330424811883e-6 3665/5434/5440/4790/1499/29110/7520/5441/4615/7098/5435/7316/55703/5970/1387/5437/2033/1660/3661/6233/7311/10621/2547/11128/7314 25 West_Nile_virus R-HSA-8856828 Clathrin-mediated endocytosis 45/1715 146/10654 6.079563664621107e-6 2.04168767043323e-5 8.98466501404608e-6 9318/1173/1839/85439/685/71/8674/4738/2069/1785/409/1080/29978/382/7316/1950/920/64708/10094/22905/26052/10980/7037/9341/10920/3482/408/10987/115548/6233/2885/6844/10097/7311/3575/6845/1956/60/3312/8673/10109/154/7314/51138/11252 45 West_Nile_virus R-HSA-169893 Prolonged ERK activation events 10/1715 14/10654 6.103375888851992e-6 2.04168767043323e-5 8.98466501404608e-6 5604/5594/673/57498/5605/10818/4914/5906/7529/5595 10 West_Nile_virus R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling 10/1715 14/10654 6.103375888851992e-6 2.04168767043323e-5 8.98466501404608e-6 5525/5526/1452/5528/5519/5529/5527/5518/5515/5516 10 West_Nile_virus R-HSA-4839744 truncated APC mutants destabilize the destruction complex 10/1715 14/10654 6.103375888851992e-6 2.04168767043323e-5 8.98466501404608e-6 5525/5526/1452/5528/5519/5529/5527/5518/5515/5516 10 West_Nile_virus R-HSA-4839748 AMER1 mutants destabilize the destruction complex 10/1715 14/10654 6.103375888851992e-6 2.04168767043323e-5 8.98466501404608e-6 5525/5526/1452/5528/5519/5529/5527/5518/5515/5516 10 West_Nile_virus R-HSA-5467337 APC truncation mutants have impaired AXIN binding 10/1715 14/10654 6.103375888851992e-6 2.04168767043323e-5 8.98466501404608e-6 5525/5526/1452/5528/5519/5529/5527/5518/5515/5516 10 West_Nile_virus R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 10/1715 14/10654 6.103375888851992e-6 2.04168767043323e-5 8.98466501404608e-6 5525/5526/1452/5528/5519/5529/5527/5518/5515/5516 10 West_Nile_virus R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 10/1715 14/10654 6.103375888851992e-6 2.04168767043323e-5 8.98466501404608e-6 5525/5526/1452/5528/5519/5529/5527/5518/5515/5516 10 West_Nile_virus R-HSA-8983432 Interleukin-15 signaling 10/1715 14/10654 6.103375888851992e-6 2.04168767043323e-5 8.98466501404608e-6 6464/3561/3560/6774/3718/6654/2885/3716/9846/6655 10 West_Nile_virus R-HSA-918233 TRAF3-dependent IRF activation pathway 10/1715 14/10654 6.103375888851992e-6 2.04168767043323e-5 8.98466501404608e-6 3665/29110/57506/7706/23586/1387/2033/64135/3661/3456 10 West_Nile_virus R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 18/1715 38/10654 6.284356583669418e-6 2.0969068296902007e-5 9.22766283171712e-6 1072/6627/6775/5908/9987/4478/3313/3185/3936/6647/5898/3458/3181/998/4001/375/5062/3586 18 West_Nile_virus R-HSA-5633007 Regulation of TP53 Activity 48/1715 160/10654 6.907654879163128e-6 2.2990629118022734e-5 1.0117272297764177e-5 1017/6118/5305/1029/7486/207/9212/1460/545/580/7316/6872/890/1457/983/6790/1108/8148/5519/6119/4683/83860/6794/5985/54815/2033/1111/7157/1107/5371/6233/5527/79109/2475/672/7311/5518/10419/5300/6117/11198/5810/26155/7314/253260/4193/5515/5516 48 West_Nile_virus R-HSA-69618 Mitotic Spindle Checkpoint 37/1715 112/10654 6.9498889189186945e-6 2.3072930970112946e-5 1.0153490108243937e-5 5905/4928/81929/55143/5525/1783/7321/5526/8697/9212/79023/57122/64105/6232/332/8881/5528/5501/5519/5529/51529/64682/29945/10393/11004/5527/7514/9184/5518/5347/29882/6396/25909/140735/996/5515/5516 37 West_Nile_virus R-HSA-114604 GPVI-mediated activation cascade 17/1715 35/10654 7.433531843289595e-6 2.4616570275014287e-5 1.083278509826122e-5 5295/5777/5590/5290/5291/6850/8503/146850/4067/5294/2534/998/3932/387/5296/5781/5879 17 West_Nile_virus R-HSA-432142 Platelet sensitization by LDL 11/1715 17/10654 8.76683761895124e-6 2.8959127773879034e-5 1.2743773982435387e-5 5777/5525/5526/5528/5519/5529/5527/5518/5781/5515/5516 11 West_Nile_virus R-HSA-5218920 VEGFR2 mediated vascular permeability 15/1715 29/10654 9.691214397996589e-6 3.193255144139876e-5 1.4052260877095054e-5 1495/1499/207/1500/1003/3320/5063/3728/79109/2475/5058/801/5062/5879/253260 15 West_Nile_virus R-HSA-170968 Frs2-mediated activation 9/1715 12/10654 9.838782677446479e-6 3.201855696018385e-5 1.4090108525725821e-5 5604/5594/673/5605/10818/4914/5906/7529/5595 9 West_Nile_virus R-HSA-1839130 Signaling by activated point mutants of FGFR3 9/1715 12/10654 9.838782677446479e-6 3.201855696018385e-5 1.4090108525725821e-5 8823/8074/8817/2254/2249/26281/2261/2247/2246 9 West_Nile_virus R-HSA-2033514 FGFR3 mutant receptor activation 9/1715 12/10654 9.838782677446479e-6 3.201855696018385e-5 1.4090108525725821e-5 8823/8074/8817/2254/2249/26281/2261/2247/2246 9 West_Nile_virus R-HSA-9020558 Interleukin-2 signaling 9/1715 12/10654 9.838782677446479e-6 3.201855696018385e-5 1.4090108525725821e-5 6464/3561/3560/6850/3718/3558/3716/3932/3559 9 West_Nile_virus R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 9/1715 12/10654 9.838782677446479e-6 3.201855696018385e-5 1.4090108525725821e-5 5295/5290/5291/4067/3717/5294/8660/5293/2549 9 West_Nile_virus R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 24/1715 61/10654 1.0649571755000054e-5 3.457176249529574e-5 1.5213673935714364e-5 1072/71/5747/4627/10458/4771/5594/2209/6850/10094/10163/3320/55845/998/695/2885/3326/10097/23191/60/5058/10109/5879/5595 24 West_Nile_virus R-HSA-5358351 Signaling by Hedgehog 45/1715 149/10654 1.095026887774598e-5 3.546057587437151e-5 1.560480577172646e-5 8454/57154/5718/5689/8945/5684/5682/1452/5690/79809/5717/409/79577/112/114/10381/7289/10197/5573/8452/2737/84447/7316/10213/9978/2778/8650/5711/5687/5685/5708/5692/5686/408/5702/83737/5719/6233/7311/6469/115/5694/5693/5691/7314 45 West_Nile_virus R-HSA-5358346 Hedgehog ligand biogenesis 25/1715 65/10654 1.1231479000214792e-5 3.628208167226249e-5 1.596631818657985e-5 5718/5689/5684/5682/5690/5717/10197/84447/7316/10213/5711/5687/5685/5708/5692/5686/5702/5719/6233/7311/6469/5694/5693/5691/7314 25 West_Nile_virus R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 21/1715 50/10654 1.1434338997358994e-5 3.6847087526941696e-5 1.6214955057379503e-5 5718/5689/5684/5682/5690/5717/2209/10197/10213/5711/5687/5685/5708/5692/5686/5702/5719/9902/5694/5693/5691 21 West_Nile_virus R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 35/1715 106/10654 1.2360311805667749e-5 3.973388038992706e-5 1.7485319139725107e-5 9318/1173/1839/85439/685/8674/4738/2069/409/1080/29978/7316/1950/920/64708/22905/10980/7037/9341/10920/3482/408/10987/115548/6233/2885/6844/7311/3575/6845/1956/8673/154/7314/51138 35 West_Nile_virus R-HSA-195721 Signaling by WNT 83/1715 331/10654 1.3457684334574568e-5 4.315627239165275e-5 1.8991379352927616e-5 8454/57154/5718/5689/8945/1173/815/5684/79971/7015/5579/6597/5682/5331/1499/5525/59345/864/5526/10023/207/1452/5690/5578/5532/5717/5929/409/79577/1460/10197/7534/8452/5528/55366/7316/10213/9978/1457/9559/4609/5519/5711/1387/5687/4919/23236/5685/5708/5692/5686/2033/2783/8724/2784/5529/2782/5702/5719/23513/57216/6233/5527/7514/4040/7311/79412/5518/387/8607/4343/3845/6659/5694/801/5693/5691/4920/7314/5879/5515/2787/5516 83 West_Nile_virus R-HSA-111367 SLBP independent Processing of Histone Pre-mRNAs 8/1715 10/10654 1.4718057387133505e-5 4.6856037768700385e-5 2.0619500687288484e-5 6635/134353/6637/4686/6636/6634/22916/6628 8 West_Nile_virus R-HSA-450341 Activation of the AP-1 family of transcription factors 8/1715 10/10654 1.4718057387133505e-5 4.6856037768700385e-5 2.0619500687288484e-5 3725/5601/5594/5602/2353/1386/5599/5595 8 West_Nile_virus R-HSA-74749 Signal attenuation 8/1715 10/10654 1.4718057387133505e-5 4.6856037768700385e-5 2.0619500687288484e-5 3643/6464/3667/5594/6654/2885/8660/5595 8 West_Nile_virus R-HSA-8878171 Transcriptional regulation by RUNX1 64/1715 239/10654 1.4886661237914717e-5 4.727860123270264e-5 2.080545426021816e-5 55904/5718/5689/5684/3562/8861/902/1437/5579/6597/5682/3674/6045/9021/5690/5717/5929/1460/1378/3958/6598/10197/6599/86/100506658/7316/10213/865/1457/10413/6714/2099/8850/5711/1387/5687/3558/5685/8289/5708/5692/5686/2033/6605/6602/595/3458/5702/83737/5719/5371/57492/6233/7311/4343/648/5694/6601/3559/5781/5693/4297/5691/7314 64 West_Nile_virus R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission 57/1715 206/10654 1.533045178913589e-5 4.857099869731035e-5 2.1374187590622156e-5 5923/818/1173/815/3838/8573/4893/5579/5331/2904/59345/2770/817/5578/5594/2036/112/114/10381/5573/2902/80852/6714/55327/2905/27330/2903/23236/3084/6195/2783/2784/9495/2782/816/2066/4905/1741/2906/2771/1742/1739/88/6196/1740/6197/3845/115/3265/801/5924/4747/2773/5879/5595/4193/2787 57 West_Nile_virus R-HSA-9006931 Signaling by Nuclear Receptors 76/1715 299/10654 1.863755920200438e-5 5.8907201506574986e-5 2.592274421381904e-5 5295/3725/2963/3838/596/5434/5440/5590/1839/4893/6464/685/5290/79718/6319/5747/59345/5160/5430/2770/207/5436/5594/2069/3315/5441/5438/5431/2100/5435/5433/1950/865/1655/6714/2099/4609/2962/8850/8503/1387/5437/3320/2033/5162/8243/9126/595/2783/2784/2782/5439/2066/2771/10498/3326/7514/1025/2353/1738/1386/1956/5536/5296/4343/3845/3265/801/29116/8877/5432/3480/2773/2957/5595/2787 76 West_Nile_virus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 78/1715 309/10654 1.8922087019306097e-5 5.966342270680726e-5 2.6255527443056308e-5 8454/57154/5718/5689/8945/5684/8065/64410/5682/7319/26046/7321/9021/8697/5690/7174/5717/10533/10197/9690/8881/8452/23376/7316/10213/9978/7317/54926/4008/8651/5711/23327/5687/26270/51465/23291/5685/5708/5692/5686/89910/55521/25898/55294/7328/7428/5702/8453/83737/51529/9040/63891/5719/10075/64682/29945/9246/10393/80176/6233/56658/4012/7311/6047/9320/29882/7334/92591/5930/5694/84961/29116/5693/51676/5691/9820/7314/996 78 West_Nile_virus R-HSA-111885 Opioid Signalling 31/1715 91/10654 1.903793443216637e-5 5.988543575559731e-5 2.635322666027803e-5 818/815/3838/5331/59345/2770/817/5578/5532/5594/112/114/2779/5573/5528/10768/5519/23236/2783/2784/2782/816/2771/5580/5518/115/801/2773/5515/2787/5516 31 West_Nile_virus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 13/1715 24/10654 2.0133856321433015e-5 6.318195864678265e-5 2.780389682483607e-5 596/1839/685/5747/207/5594/2069/1950/595/7514/2353/1956/5595 13 West_Nile_virus R-HSA-159227 Transport of the SLBP independent Mature mRNA 16/1715 34/10654 2.2866963725042685e-5 7.15882617330315e-5 3.15031804287999e-5 23165/4928/81929/55706/7175/9631/79023/57122/4686/9688/10189/10482/8086/1977/6396/22916 16 West_Nile_virus R-HSA-9609736 Assembly and cell surface presentation of NMDA receptors 18/1715 41/10654 2.3265719598381826e-5 7.266402471722097e-5 3.197658143853426e-5 818/815/8573/2904/817/10381/2902/55327/2905/2903/816/1741/2906/1742/1739/88/1740/4747 18 West_Nile_virus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 9/1715 13/10654 2.7386912410445068e-5 8.413974488803403e-5 3.702659486726839e-5 2065/207/2064/7316/3084/9542/6233/7311/7314 9 West_Nile_virus R-HSA-190239 FGFR3 ligand binding and activation 9/1715 13/10654 2.7386912410445068e-5 8.413974488803403e-5 3.702659486726839e-5 8823/8074/8817/2254/2249/26281/2261/2247/2246 9 West_Nile_virus R-HSA-190372 FGFR3c ligand binding and activation 9/1715 13/10654 2.7386912410445068e-5 8.413974488803403e-5 3.702659486726839e-5 8823/8074/8817/2254/2249/26281/2261/2247/2246 9 West_Nile_virus R-HSA-2995383 Initiation of Nuclear Envelope Reformation 9/1715 13/10654 2.7386912410445068e-5 8.413974488803403e-5 3.702659486726839e-5 4000/7443/7444/2010/4001/23592/5518/7112/5515 9 West_Nile_virus R-HSA-2995410 Nuclear Envelope Reassembly 9/1715 13/10654 2.7386912410445068e-5 8.413974488803403e-5 3.702659486726839e-5 4000/7443/7444/2010/4001/23592/5518/7112/5515 9 West_Nile_virus R-HSA-5654227 Phospholipase C-mediated cascade; FGFR3 9/1715 13/10654 2.7386912410445068e-5 8.413974488803403e-5 3.702659486726839e-5 8823/8074/8817/2254/2249/26281/2261/2247/2246 9 West_Nile_virus R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 9/1715 13/10654 2.7386912410445068e-5 8.413974488803403e-5 3.702659486726839e-5 7531/7532/10971/7533/2810/7534/983/1111/7529 9 West_Nile_virus R-HSA-8951664 Neddylation 62/1715 234/10654 2.8607555345692595e-5 8.768548359447172e-5 3.858693511744583e-5 8454/9318/5718/5689/54165/8945/5684/8065/64410/23363/5682/25879/7321/9021/4738/5690/5717/5929/3091/10197/332/8452/8450/7316/10213/9978/4008/64708/10980/5711/5687/26270/23291/5685/55832/5708/5692/10920/5686/55294/10987/7428/5702/8453/123879/9040/5719/80176/6233/7311/83987/8883/92591/5694/84961/5693/51676/5691/9820/7314/51138/8451 62 West_Nile_virus R-HSA-111465 Apoptotic cleavage of cellular proteins 17/1715 38/10654 2.9041240833227857e-5 8.8398049464652e-5 3.89005073516678e-5 4000/22985/1499/5747/118/1829/841/100506658/10134/999/836/4001/5580/6709/6093/839/840 17 West_Nile_virus R-HSA-5689896 Ovarian tumor domain proteases 17/1715 38/10654 2.9041240833227857e-5 8.8398049464652e-5 3.89005073516678e-5 7321/57506/7706/7316/79155/983/2099/23586/64135/5728/7157/7189/6233/7311/78990/387/7314 17 West_Nile_virus R-HSA-5696394 DNA Damage Recognition in GG-NER 17/1715 38/10654 2.9041240833227857e-5 8.8398049464652e-5 3.89005073516678e-5 9318/86/8450/7316/9978/64708/10980/283899/10920/10987/6233/7311/60/8607/7314/51138/8451 17 West_Nile_virus R-HSA-73894 DNA Repair 82/1715 334/10654 3.4415767570175315e-5 1.0451608676841259e-4 4.599342209839098e-5 10450/9318/1017/6118/25913/3838/6917/5434/5440/221120/902/5888/322/27339/7486/5430/5436/7520/5531/4292/9636/545/5441/27434/7706/86/5438/3981/580/5431/8450/5435/7316/9978/5433/890/64708/5426/10635/7517/10980/283899/6119/4683/5437/5427/5985/10920/25898/2033/2068/5439/1111/10987/2071/7157/7329/4255/9246/6233/672/7158/7311/6047/56949/60/5536/8607/9716/6117/2175/5599/7334/2547/57461/5810/79840/5432/348654/7314/51138/8451 82 West_Nile_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 10/1715 16/10654 3.5718260710503546e-5 1.0822222440561765e-4 4.762434761400473e-5 8454/8945/4790/5604/7316/79155/23291/6233/7311/7314 10 West_Nile_virus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 16/1715 35/10654 3.5863537941255755e-5 1.084131720334291e-4 4.7708376160386095e-5 23165/4928/81929/55706/7175/9631/79023/57122/4686/9688/10189/10482/8086/1977/6396/22916 16 West_Nile_virus R-HSA-2990846 SUMOylation 52/1715 188/10654 3.610422101978824e-5 1.0870392653732074e-4 4.783632579032325e-5 6095/23165/7150/5905/4928/81929/29843/55706/7175/55143/9631/1029/7486/6045/9212/4869/51602/79023/57122/2516/332/3183/1655/5970/3190/6790/2099/9688/1387/10521/2908/10055/2033/23512/8243/9126/7428/7157/1107/8086/7329/5371/672/115426/7158/10155/6117/6294/6396/648/4193/79677 52 West_Nile_virus R-HSA-5619084 ABC transporter disorders 27/1715 77/10654 3.612467361407169e-5 1.0870392653732074e-4 4.783632579032325e-5 5718/5689/5684/5682/5690/91445/5717/1080/10197/1244/7316/10213/5711/5687/5685/5708/5692/5686/5702/5719/6233/7311/11160/5694/5693/5691/7314 27 West_Nile_virus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 25/1715 69/10654 3.712729254027233e-5 1.1146645004118208e-4 4.905200381174932e-5 23165/6118/4928/81929/55706/7175/9631/7531/5594/9530/545/79023/57122/3313/9532/9688/6119/3309/6767/8086/6117/6396/3312/51182/5595 25 West_Nile_virus R-HSA-198753 ERK/MAPK targets 12/1715 22/10654 3.862549234196729e-5 1.1543854627372537e-4 5.0799967252473984e-5 9252/5594/5528/5519/6195/6196/5518/6197/51231/5595/5515/5516 12 West_Nile_virus R-HSA-9613829 Chaperone Mediated Autophagy 12/1715 22/10654 3.862549234196729e-5 1.1543854627372537e-4 5.0799967252473984e-5 1915/1080/5116/7316/3320/123/6233/3326/7311/200894/3312/7314 12 West_Nile_virus R-HSA-176412 Phosphorylation of the APC/C 11/1715 19/10654 3.908231660741256e-5 1.1653957757594966e-4 5.128448785588073e-5 7321/8697/8881/983/51529/64682/29945/10393/5347/29882/996 11 West_Nile_virus R-HSA-397795 G-protein beta:gamma signalling 15/1715 32/10654 4.368483471798645e-5 1.299697791383886e-4 5.7194591730095134e-5 5331/59345/207/9459/146850/23236/5294/2783/2784/2782/998/695/387/5058/2787 15 West_Nile_virus R-HSA-1839122 Signaling by activated point mutants of FGFR1 8/1715 11/10654 4.630572206791135e-5 1.3714818356293742e-4 6.035352539188446e-5 8074/2260/2254/2249/26281/2247/2246/2251 8 West_Nile_virus R-HSA-77588 SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs 8/1715 11/10654 4.630572206791135e-5 1.3714818356293742e-4 6.035352539188446e-5 6635/134353/6637/4686/6636/6634/22916/6628 8 West_Nile_virus R-HSA-6807505 RNA polymerase II transcribes snRNA genes 26/1715 74/10654 4.817174429306143e-5 1.4235506497366584e-4 6.264486926003505e-5 2963/5434/5440/2959/5430/5436/51585/5441/5438/5431/5435/4686/5433/2960/2962/51808/5437/5439/1025/6621/51593/2961/65123/5432/22916/2957 26 West_Nile_virus R-HSA-6790901 rRNA modification in the nucleus and cytosol 23/1715 62/10654 4.90429024042746e-5 1.44605246910143e-4 6.363508589368965e-5 9136/2091/6203/55651/55813/6194/25879/27292/10528/4839/88745/51602/134430/55272/92856/9790/51077/10199/55505/6201/51202/6187/6208 23 West_Nile_virus R-HSA-163685 Integration of energy metabolism 34/1715 108/10654 4.993556705655993e-5 1.4670690172349503e-4 6.455994157786581e-5 5313/9254/5331/59345/2770/5578/112/114/4082/5573/5528/2778/10768/5519/23236/6794/2783/2784/9495/2782/2776/2771/7086/6844/8826/5906/2182/5518/115/31/2181/5515/2787/5516 34 West_Nile_virus R-HSA-5619115 Disorders of transmembrane transporters 49/1715 176/10654 4.997829960079611e-5 1.4670690172349503e-4 6.455994157786581e-5 5718/23165/5689/4928/6507/81929/5684/55706/7175/5682/9631/5690/91445/5717/1080/7355/79023/9843/57122/10197/1244/7316/10213/3098/9688/5711/5687/5685/682/5708/5692/5686/5702/8086/4891/1836/5719/6520/6233/7311/6575/11160/6396/5694/9197/5693/5691/6566/7314 49 West_Nile_virus R-HSA-2559583 Cellular Senescence 53/1715 195/10654 5.116490017303001e-5 1.4985630761789678e-4 6.594587133412756e-5 1017/3725/25913/1019/5601/4790/9448/3159/1029/7321/2146/6045/8697/5594/50488/3576/8881/7316/890/6774/5970/1026/3552/4683/5602/23512/6195/7157/51529/4001/64682/29945/10393/8091/5609/6233/2353/6196/7311/57634/4343/8726/6197/29882/5599/648/3456/3569/7314/996/5595/4193/23043 53 West_Nile_virus R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 14/1715 29/10654 5.226579059493682e-5 1.527412683018331e-4 6.721542914648194e-5 5434/5440/5430/5436/5441/5438/5431/5435/5433/5437/84944/3320/5439/5432 14 West_Nile_virus R-HSA-168638 NOD1/2 Signaling Pathway 16/1715 36/10654 5.4968587711958025e-5 1.5993068124582933e-4 7.037920722502352e-5 834/842/835/841/7316/837/3656/5603/83737/3654/7189/6233/7311/7334/1540/7314 16 West_Nile_virus R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 16/1715 36/10654 5.4968587711958025e-5 1.5993068124582933e-4 7.037920722502352e-5 71/5747/10458/5594/10094/10163/55845/998/695/2885/10097/23191/60/10109/5879/5595 16 West_Nile_virus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 50/1715 182/10654 6.126904623435512e-5 1.778691694644935e-4 7.827323087208363e-5 6095/23165/7150/5905/4928/81929/55706/7175/55143/9631/1029/7486/6045/9212/4869/51602/79023/57122/2516/332/3183/1655/5970/3190/6790/2099/9688/1387/10521/2908/2033/23512/8243/9126/7428/7157/1107/8086/7329/5371/672/115426/7158/10155/6117/6294/6396/648/4193/79677 50 West_Nile_virus R-HSA-70171 Glycolysis 25/1715 71/10654 6.425105919044235e-5 1.86116254973633e-4 8.19024490779265e-5 23165/4928/81929/5313/2597/55706/7175/9631/5315/79023/57122/5214/5528/5230/3098/9688/5519/2023/226/2821/8086/5518/6396/5515/5516 25 West_Nile_virus R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 9/1715 14/10654 6.56972781493125e-5 1.8947267527526013e-4 8.33794777387336e-5 5862/5594/5861/9133/26003/983/8548/5347/5595 9 West_Nile_virus R-HSA-9027284 Erythropoietin activates RAS 9/1715 14/10654 6.56972781493125e-5 1.8947267527526013e-4 8.33794777387336e-5 4893/6464/4067/3717/6654/2885/8660/3845/3265 9 West_Nile_virus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 30/1715 92/10654 6.585459012428476e-5 1.89511680750671e-4 8.33966425154698e-5 1017/6118/7486/9212/1460/545/580/7316/6872/890/1457/6790/8148/6119/4683/83860/6794/5985/1111/7157/6233/672/7311/5300/6117/11198/5810/26155/7314/4193 30 West_Nile_virus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 12/1715 23/10654 6.895793834324785e-5 1.9800994060218012e-4 8.713639267774239e-5 5601/7316/5602/3656/3654/7189/5609/6233/7311/5599/7334/7314 12 West_Nile_virus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 28/1715 84/10654 7.37735039924053e-5 2.1137712665650042e-4 9.301876590346757e-5 9318/6118/902/86/8450/7316/9978/64708/5426/10980/283899/6119/5427/5985/10920/2068/10987/2071/7329/6233/7311/60/8607/6117/7334/7314/51138/8451 28 West_Nile_virus R-HSA-202733 Cell surface interactions at the vascular wall 40/1715 137/10654 7.698516373444265e-5 2.201007501127883e-4 9.685768973096907e-5 5295/5777/4893/6464/5290/960/5291/2995/1525/7010/83700/3678/50848/3688/8140/6714/4973/4067/140885/682/2335/2534/3690/6520/6654/2885/7525/23657/3932/5296/3845/3265/5781/481/5627/6566/3676/284/9046/3655 40 West_Nile_virus R-HSA-75153 Apoptotic execution phase 20/1715 52/10654 8.350685979407079e-5 2.3738915961858816e-4 1.044656392858734e-4 4000/22985/1499/5747/10059/118/1829/841/100506658/3146/10134/999/836/4001/5580/6709/6093/839/840/5062 20 West_Nile_virus R-HSA-3928663 EPHA-mediated growth cone collapse 14/1715 30/10654 8.355459795811857e-5 2.3738915961858816e-4 1.044656392858734e-4 2042/4627/2041/6714/4637/4067/2043/2534/9475/4628/7525/6093/387/1969 14 West_Nile_virus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 25/1715 72/10654 8.357251142869871e-5 2.3738915961858816e-4 1.044656392858734e-4 8773/55763/71/7531/4627/7532/207/10971/57186/7533/2810/10381/7534/5872/60412/5898/11336/51552/6844/4012/60/801/7529/6814/5879 25 West_Nile_virus R-HSA-4615885 SUMOylation of DNA replication proteins 18/1715 45/10654 1.0347946211483054e-4 2.933030775641863e-4 1.290711570464553e-4 23165/7150/5905/4928/81929/55706/7175/55143/9631/9212/79023/57122/332/6790/9688/8086/7329/6396 18 West_Nile_virus R-HSA-203927 MicroRNA (miRNA) biogenesis 12/1715 24/10654 1.1778202036506232e-4 3.32412639916814e-4 1.4628173835489538e-4 5434/5440/5430/5436/5441/5438/5431/5435/5433/5437/5439/5432 12 West_Nile_virus R-HSA-982772 Growth hormone receptor signaling 12/1715 24/10654 1.1778202036506232e-4 3.32412639916814e-4 1.4628173835489538e-4 5777/3667/5770/9021/5594/6774/6772/8651/4067/3717/8660/5595 12 West_Nile_virus R-HSA-190373 FGFR1c ligand binding and activation 8/1715 12/10654 1.1923960084884126e-4 3.329614277940101e-4 1.4652323833120326e-4 8074/2260/2254/2249/26281/2247/2246/2251 8 West_Nile_virus R-HSA-210990 PECAM1 interactions 8/1715 12/10654 1.1923960084884126e-4 3.329614277940101e-4 1.4652323833120326e-4 5777/6714/4067/2534/3690/7525/3932/5781 8 West_Nile_virus R-HSA-389359 CD28 dependent Vav1 pathway 8/1715 12/10654 1.1923960084884126e-4 3.329614277940101e-4 1.4652323833120326e-4 5063/2534/998/2885/3932/5058/5062/5879 8 West_Nile_virus R-HSA-8984722 Interleukin-35 Signalling 8/1715 12/10654 1.1923960084884126e-4 3.329614277940101e-4 1.4652323833120326e-4 6775/821/6774/6772/3717/3716/7297/3572 8 West_Nile_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 8/1715 12/10654 1.1923960084884126e-4 3.329614277940101e-4 1.4652323833120326e-4 3665/29110/7098/7316/3661/6233/7311/7314 8 West_Nile_virus R-HSA-399719 Trafficking of AMPA receptors 14/1715 31/10654 1.2992962477337684e-4 3.6128110854706893e-4 1.58985616811305e-4 818/1173/815/5579/817/5578/2036/80852/9495/816/4905/1742/1739/4193 14 West_Nile_virus R-HSA-399721 Glutamate binding, activation of AMPA receptors and synaptic plasticity 14/1715 31/10654 1.2992962477337684e-4 3.6128110854706893e-4 1.58985616811305e-4 818/1173/815/5579/817/5578/2036/80852/9495/816/4905/1742/1739/4193 14 West_Nile_virus R-HSA-111447 Activation of BAD and translocation to mitochondria 9/1715 15/10654 1.4075534997190972e-4 3.9055905529047794e-4 1.7186969049201608e-4 596/7531/7532/207/10971/7533/2810/7534/7529 9 West_Nile_virus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 10/1715 18/10654 1.429227320858982e-4 3.9573983380086937e-4 1.7414954749962386e-4 3665/29110/7099/7316/929/3661/6233/7311/5781/7314 10 West_Nile_virus R-HSA-6794362 Protein-protein interactions at synapses 28/1715 87/10654 1.4702414385508818e-4 4.062428125807258e-4 1.7877149567285358e-4 8573/8496/2035/2904/10211/2319/2036/26050/2902/23136/22839/57669/9369/55327/2905/8500/2903/2037/84631/9066/1741/2906/1742/1739/1740/8495/4916/3556 28 West_Nile_virus R-HSA-112043 PLC beta mediated events 20/1715 54/10654 1.5402966672086236e-4 4.247094157700765e-4 1.8689792196255266e-4 818/815/3838/5331/2770/817/5578/5594/112/114/2779/5573/10768/23236/816/2771/5580/115/801/2773 20 West_Nile_virus R-HSA-917937 Iron uptake and transport 21/1715 58/10654 1.5446673389054013e-4 4.250253763418203e-4 1.8703696379230328e-4 8454/28982/55240/4738/9550/9114/3163/9843/7316/3658/527/7037/245972/55832/533/4891/6233/7311/3162/51382/7314 21 West_Nile_virus R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 12/1715 25/10654 1.9347824965089885e-4 5.312590271664264e-4 2.3378621832816944e-4 9252/5594/5528/5519/6195/6196/5518/6197/51231/5595/5515/5516 12 West_Nile_virus R-HSA-194315 Signaling by Rho GTPases 102/1715 455/10654 1.9971195755614905e-4 5.47235675798346e-4 2.4081691347726915e-4 85415/3831/5905/4928/9743/445328/81929/5590/1072/27035/71/55143/5579/1495/1499/5525/392/7531/5747/1783/55789/57580/5526/4627/7532/2909/10928/10971/10458/4771/5578/9212/5594/7074/9459/1080/7533/2810/79023/10381/57122/64105/6232/7534/332/5528/3688/5501/10094/6279/6714/5519/4637/10163/999/1123/55845/5063/9475/3895/57514/57584/5529/998/4628/695/10788/2/11004/1742/6654/5527/2885/5580/10097/23191/7514/6093/9184/8826/5518/26084/5347/387/6655/60/5296/5300/6396/25909/5058/801/10109/5062/5924/140735/5500/7529/5879/5595/5515/5516 102 West_Nile_virus R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 19/1715 51/10654 2.0464159333625245e-4 5.584215735345358e-4 2.457393874431189e-4 5718/5689/5684/5682/5690/5717/10197/10213/5711/5687/5685/5708/5692/5686/5702/5719/5694/5693/5691 19 West_Nile_virus R-HSA-3928665 EPH-ephrin mediated repulsion of cells 19/1715 51/10654 2.0464159333625245e-4 5.584215735345358e-4 2.457393874431189e-4 1173/71/2042/1947/7074/1949/2041/102/6714/4067/2043/2534/1948/2048/7525/60/5663/1969/5879 19 West_Nile_virus R-HSA-112040 G-protein mediated events 20/1715 55/10654 2.0585984742253784e-4 5.605852869894728e-4 2.4669155269642964e-4 818/815/3838/5331/2770/817/5578/5594/112/114/2779/5573/10768/23236/816/2771/5580/115/801/2773 20 West_Nile_virus R-HSA-190377 FGFR2b ligand binding and activation 7/1715 10/10654 2.115676492268287e-4 5.749405395483716e-4 2.53008735157857e-4 2263/2248/2247/2255/27006/2246/2252 7 West_Nile_virus R-HSA-71291 Metabolism of amino acids and derivatives 86/1715 372/10654 2.1496034447939143e-4 5.829583004605719e-4 2.5653703662149597e-4 5718/5689/6138/6144/38/6203/5684/6194/6234/6191/6128/5682/6132/6147/9521/6129/5160/3028/4143/9255/6222/6152/5690/6136/6125/5717/11185/6224/6146/6154/6141/10197/6232/6134/60678/6160/10213/7299/8140/6205/6165/6142/9061/5711/5687/162417/5685/5708/7965/5692/5686/5162/6156/6235/6124/5702/26227/6207/5719/6139/6520/6233/7311/6223/25873/1738/3921/6188/6135/5860/6201/36/6161/5694/6187/9060/6168/5693/6208/6157/6170/5691/200916/6535/6122/6230 86 West_Nile_virus R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 38/1715 134/10654 2.2362784234765287e-4 6.052186780579188e-4 2.6633295392533606e-4 5099/351/1072/5579/3674/7094/7422/5578/3082/7414/10490/334/1950/51706/308/710/6647/7273/226/374354/2244/1893/3309/2335/3690/2/94121/10487/88/2266/5155/2243/7450/29789/801/350/5627/6814 38 West_Nile_virus R-HSA-177243 Interactions of Rev with host cellular proteins 15/1715 36/10654 2.267984420698344e-4 6.125416939509053e-4 2.695555254108688e-4 23165/5905/4928/81929/55706/7175/9631/4869/79023/57122/9688/5902/8086/7514/6396 15 West_Nile_virus R-HSA-3928664 Ephrin signaling 10/1715 19/10654 2.5830097150643784e-4 6.961977105224643e-4 3.0636925045753364e-4 1947/1949/6714/5063/2534/1948/2048/5058/5062/5879 10 West_Nile_virus R-HSA-69231 Cyclin D associated events in G1 17/1715 44/10654 2.636324550496095e-4 7.076732703775669e-4 3.114191933376243e-4 8454/1019/902/1029/7316/1026/6714/5519/4067/3717/595/6233/7311/5518/7314/5515/5516 17 West_Nile_virus R-HSA-69236 G1 Phase 17/1715 44/10654 2.636324550496095e-4 7.076732703775669e-4 3.114191933376243e-4 8454/1019/902/1029/7316/1026/6714/5519/4067/3717/595/6233/7311/5518/7314/5515/5516 17 West_Nile_virus R-HSA-171007 p38MAPK events 8/1715 13/10654 2.662039023502752e-4 7.116769640926221e-4 3.1318106158855906e-4 4893/5899/6714/5898/5603/5900/3845/3265 8 West_Nile_virus R-HSA-202670 ERKs are inactivated 8/1715 13/10654 2.662039023502752e-4 7.116769640926221e-4 3.1318106158855906e-4 5594/5528/5519/5518/51231/5595/5515/5516 8 West_Nile_virus R-HSA-205043 NRIF signals cell death from the nucleus 9/1715 16/10654 2.7580303616514605e-4 7.328798420678679e-4 3.225116148705337e-4 4804/8878/7316/7189/6233/7311/5599/5663/7314 9 West_Nile_virus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 9/1715 16/10654 2.7580303616514605e-4 7.328798420678679e-4 3.225116148705337e-4 57154/5590/50848/7316/6233/7311/56288/387/7314 9 West_Nile_virus R-HSA-399954 Sema3A PAK dependent Axon repulsion 9/1715 16/10654 2.7580303616514605e-4 7.328798420678679e-4 3.225116148705337e-4 1072/5361/3320/5063/2534/3326/5058/5062/5879 9 West_Nile_virus R-HSA-112315 Transmission across Chemical Synapses 66/1715 272/10654 2.7846634441414163e-4 7.384680924302588e-4 3.249707842257589e-4 5923/818/1173/6507/815/3838/8573/4893/9254/5579/5331/2904/59345/2770/817/5578/5594/2036/112/114/10381/5573/2902/80852/6714/54407/55327/2905/8500/81539/27330/2903/23236/3084/6195/2783/2784/9495/2782/816/2066/4905/1741/2906/2771/10550/1742/1739/22999/6844/88/6196/1740/6197/3845/115/3265/3312/801/5924/4747/2773/5879/5595/4193/2787 66 West_Nile_virus R-HSA-373755 Semaphorin interactions 22/1715 65/10654 3.319635676614972e-4 8.785702453370548e-4 3.8662423542905295e-4 10154/1072/5361/4627/2909/7094/2064/3688/4233/4637/3320/5063/2534/9475/4628/3326/6093/10507/387/5058/5062/5879 22 West_Nile_virus R-HSA-8943724 Regulation of PTEN gene transcription 21/1715 61/10654 3.45926033030141e-4 9.136883998671861e-4 4.0207835502501356e-4 3725/2146/6045/5594/1108/10014/54815/23512/6615/7157/1107/10542/2475/55004/57504/1386/8726/648/64121/57521/5595 21 West_Nile_virus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 13/1715 30/10654 3.7303067603408895e-4 9.807916717594924e-4 4.316078676938587e-4 6118/8450/7316/9978/5426/6119/5427/5985/6233/7311/6117/7314/8451 13 West_Nile_virus R-HSA-114452 Activation of BH3-only proteins 13/1715 30/10654 3.7303067603408895e-4 9.807916717594924e-4 4.316078676938587e-4 596/10018/7531/7532/207/10971/7533/2810/7534/7157/5599/140735/7529 13 West_Nile_virus R-HSA-112409 RAF-independent MAPK1/3 activation 11/1715 23/10654 3.7356405100399487e-4 9.807916717594924e-4 4.316078676938587e-4 5604/5594/983/5605/3717/3716/7297/5781/3569/3572/5595 11 West_Nile_virus R-HSA-165054 Rev-mediated nuclear export of HIV RNA 14/1715 34/10654 4.233774524051816e-4 0.0011093667639563206 4.8818871251492106e-4 23165/5905/4928/81929/55706/7175/9631/79023/57122/9688/5902/8086/7514/6396 14 West_Nile_virus R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 10/1715 20/10654 4.423745576134722e-4 0.0011522720690406252 5.07069651019395e-4 7321/8697/8881/51529/64682/29945/10393/9184/29882/996 10 West_Nile_virus R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 10/1715 20/10654 4.423745576134722e-4 0.0011522720690406252 5.07069651019395e-4 7321/8697/8881/51529/64682/29945/10393/9184/29882/996 10 West_Nile_virus R-HSA-8876384 Listeria monocytogenes entry into host cells 10/1715 20/10654 4.423745576134722e-4 0.0011522720690406252 5.07069651019395e-4 1499/7316/1500/4233/6714/999/6233/2885/7311/7314 10 West_Nile_virus R-HSA-1500931 Cell-Cell communication 36/1715 129/10654 4.5273818399699613e-4 0.0011769406834478125 5.179253386947884e-4 5295/5777/8573/6711/1365/9076/5290/71/5291/1495/1499/5584/5747/9459/50848/3688/1500/23705/6714/1003/140885/999/2534/10979/3728/64398/2885/6709/88/56288/8826/60/5296/55742/5781/3655 36 West_Nile_virus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 15/1715 38/10654 4.581460269136696e-4 0.0011863191816742955 5.220524471707827e-4 23165/4928/81929/55706/7175/9631/79023/57122/9688/7428/8086/7329/5371/6396/4193 15 West_Nile_virus R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 15/1715 38/10654 4.581460269136696e-4 0.0011863191816742955 5.220524471707827e-4 6597/6045/1460/6598/6599/86/865/1457/8289/2033/6605/6602/57492/648/6601 15 West_Nile_virus R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 16/1715 42/10654 4.788538727844315e-4 0.0012375086359409427 5.445789141470006e-4 10694/59345/2770/1460/2779/7203/10576/1457/2783/2784/2782/2771/10574/22948/2773/2787 16 West_Nile_virus R-HSA-8875555 MET activates RAP1 and RAC1 7/1715 11/10654 5.007760217549346e-4 0.0012891070247519607 5.67285337144262e-4 5908/3082/4233/2885/5906/2549/5879 7 West_Nile_virus R-HSA-9020956 Interleukin-27 signaling 7/1715 11/10654 5.007760217549346e-4 0.0012891070247519607 5.67285337144262e-4 821/6774/6772/3717/3716/7297/3572 7 West_Nile_virus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 30/1715 102/10654 5.062188065335614e-4 0.0013005777524585458 5.72333153585703e-4 8454/7124/5718/5689/8945/5684/5682/5690/5717/10197/7316/10213/8741/5711/5687/23291/5685/5708/5692/5686/5702/60401/9040/5719/6233/7311/5694/5693/5691/7314 30 West_Nile_virus R-HSA-428540 Activation of RAC1 8/1715 14/10654 5.335460679515574e-4 0.0013681200730742272 6.020558743422244e-4 10298/6091/5063/6654/6655/5058/5062/5879 8 West_Nile_virus R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 13/1715 31/10654 5.486036575001582e-4 0.0014039992632722497 6.17844895825421e-4 1499/5525/5526/10023/1452/5528/5519/5529/5527/4040/5518/5515/5516 13 West_Nile_virus R-HSA-3371571 HSF1-dependent transactivation 11/1715 24/10654 5.899950000061673e-4 0.0015040878336714284 6.618899419798396e-4 818/815/817/1387/3320/2033/816/3326/2475/3312/57521 11 West_Nile_virus R-HSA-5627123 RHO GTPases activate PAKs 11/1715 24/10654 5.899950000061673e-4 0.0015040878336714284 6.618899419798396e-4 4627/4771/4637/5063/998/4628/5058/801/5062/5500/5879 11 West_Nile_virus R-HSA-2172127 DAP12 interactions 16/1715 43/10654 6.500468610591106e-4 0.0016432630774793648 7.231354969180816e-4 5295/9402/4893/6464/5290/5291/6850/2534/695/6654/2885/3932/5296/3845/3265/5879 16 West_Nile_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 17/1715 47/10654 6.508219472262734e-4 0.0016432630774793648 7.231354969180816e-4 8454/79718/23462/3091/7316/9978/4609/10014/22938/8850/1387/2033/55294/6233/7311/4851/7314 17 West_Nile_virus R-HSA-437239 Recycling pathway of L1 17/1715 47/10654 6.508219472262734e-4 0.0016432630774793648 7.231354969180816e-4 1173/9252/71/7430/5594/1785/10381/4478/8650/6714/26052/27330/6195/6196/24137/60/6197 17 West_Nile_virus R-HSA-4570464 SUMOylation of RNA binding proteins 17/1715 47/10654 6.508219472262734e-4 0.0016432630774793648 7.231354969180816e-4 23165/4928/81929/55706/7175/9631/6045/51602/79023/57122/3183/3190/9688/8086/7329/6396/648 17 West_Nile_virus R-HSA-6783783 Interleukin-10 signaling 17/1715 47/10654 6.508219472262734e-4 0.0016432630774793648 7.231354969180816e-4 3557/7124/1437/3553/5743/3383/3576/6352/6774/3627/3552/3716/3588/7297/3569/3586/3554 17 West_Nile_virus R-HSA-157118 Signaling by NOTCH 57/1715 235/10654 7.115906116976346e-4 0.0017932627652341919 7.891444642153501e-4 8454/5718/23286/5689/3725/5684/79718/5682/5584/23462/207/4904/5690/5717/409/3091/10197/7534/7316/10213/9978/1950/8650/102/6772/4609/10014/5870/22938/8850/5711/1387/5687/5685/5708/5692/5686/2033/408/595/55294/4853/5702/7157/83737/5719/6233/7311/1956/4343/5694/4851/5693/5663/10959/5691/7314 57 West_Nile_virus R-HSA-68877 Mitotic Prometaphase 50/1715 200/10654 7.185443131738049e-4 0.0018073309251203718 7.953353084748222e-4 115106/5905/4928/81929/55143/5525/7531/10142/1783/5526/7532/9212/121441/1460/79023/9133/10381/57122/64105/5116/6232/332/5528/5501/1457/983/9702/5519/3320/8243/9126/10426/5529/9918/10540/4751/11004/5527/7514/9184/5518/5347/113130/6396/25909/27229/140735/10806/5515/5516 50 West_Nile_virus R-HSA-8849932 Synaptic adhesion-like molecules 10/1715 21/10654 7.233930831575581e-4 0.0018160611116222127 7.991771204407308e-4 2904/10211/2319/2902/2905/2903/1741/2906/1742/1739 10 West_Nile_virus R-HSA-1980143 Signaling by NOTCH1 23/1715 73/10654 7.797943185594257e-4 0.001953933292512021 8.598492486016483e-4 8454/79718/23462/409/3091/7316/9978/8650/102/4609/10014/22938/8850/1387/2033/408/55294/83737/6233/7311/4851/5663/7314 23 West_Nile_virus R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 13/1715 32/10654 7.891684875235089e-4 0.0019699319442348195 8.668896264462787e-4 59345/5594/409/6714/408/2783/2784/2768/2782/2776/9002/5595/2787 13 West_Nile_virus R-HSA-5656169 Termination of translesion DNA synthesis 13/1715 32/10654 7.891684875235089e-4 0.0019699319442348195 8.668896264462787e-4 6118/9636/7706/7316/5426/6119/5427/5985/9246/6233/7311/6117/7314 13 West_Nile_virus R-HSA-73893 DNA Damage Bypass 17/1715 48/10654 8.586699154252372e-4 0.0021393704131010636 9.414528373282374e-4 6118/9636/7706/8450/7316/9978/5426/6119/5427/5985/25898/9246/6233/7311/6117/7314/8451 17 West_Nile_virus R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 9/1715 18/10654 8.622445107944924e-4 0.002144223141938002 9.435883325675578e-4 5295/8805/11052/5290/6774/6772/2885/9846/7750 9 West_Nile_virus R-HSA-9612973 Autophagy 33/1715 119/10654 8.651028139073693e-4 0.0021468690758958734 9.447527041119929e-4 79643/65018/1915/8878/1080/1460/10533/5116/91782/7316/1457/6714/56993/89853/3320/55054/123/55669/10542/6233/3326/2475/55004/9804/7311/200894/93343/3312/64121/57521/7248/140735/7314 33 West_Nile_virus R-HSA-168276 NS1 Mediated Effects on Host Pathways 15/1715 40/10654 8.665662734268625e-4 0.0021468690758958734 9.447527041119929e-4 23165/4928/3838/81929/55706/7175/9631/8106/9636/79023/57122/9688/10898/8086/6396 15 West_Nile_virus R-HSA-422356 Regulation of insulin secretion 24/1715 78/10654 8.839883480858331e-4 0.0021843145153939143 9.612309703554405e-4 9254/5331/59345/2770/5578/112/114/4082/5573/2778/10768/23236/2783/2784/9495/2782/2776/2771/6844/8826/5906/2182/2181/2787 24 West_Nile_virus R-HSA-141424 Amplification of signal from the kinetochores 28/1715 96/10654 8.866527054140701e-4 0.0021843145153939143 9.612309703554405e-4 5905/4928/81929/55143/5525/1783/5526/9212/79023/57122/64105/6232/332/5528/5501/5519/5529/11004/5527/7514/9184/5518/5347/6396/25909/140735/5515/5516 28 West_Nile_virus R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 28/1715 96/10654 8.866527054140701e-4 0.0021843145153939143 9.612309703554405e-4 5905/4928/81929/55143/5525/1783/5526/9212/79023/57122/64105/6232/332/5528/5501/5519/5529/11004/5527/7514/9184/5518/5347/6396/25909/140735/5515/5516 28 West_Nile_virus R-HSA-400685 Sema4D in semaphorin signaling 11/1715 25/10654 9.015438752853074e-4 0.0022127277981862856 9.737345394142987e-4 4627/2909/2064/4233/4637/9475/4628/6093/10507/387/5879 11 West_Nile_virus R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 11/1715 25/10654 9.015438752853074e-4 0.0022127277981862856 9.737345394142987e-4 1017/902/9133/890/983/5519/7514/5518/5347/5515/5516 11 West_Nile_virus R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 31/1715 110/10654 9.145005516037387e-4 0.0022403563699139916 9.858927879742908e-4 1017/3725/1019/4790/1029/7321/8697/5594/3576/8881/7316/890/6774/5970/1026/3552/6195/51529/64682/29945/10393/6233/2353/6196/7311/6197/29882/3569/7314/996/5595 31 West_Nile_virus R-HSA-114608 Platelet degranulation 35/1715 129/10654 9.43095964537012e-4 0.002306123341854883 0.0010148342475537423 5099/351/1072/3674/7094/7422/3082/7414/10490/334/1950/51706/308/710/6647/7273/226/374354/2244/1893/3309/2335/3690/2/94121/10487/88/2266/5155/2243/7450/29789/801/350/5627 35 West_Nile_virus R-HSA-4419969 Depolymerisation of the Nuclear Lamina 8/1715 15/10654 9.824497456425829e-4 0.0023890567615441408 0.0010513299861119889 4000/5579/5578/983/2010/4001/23592/7112 8 West_Nile_virus R-HSA-937039 IRAK1 recruits IKK complex 8/1715 15/10654 9.824497456425829e-4 0.0023890567615441408 0.0010513299861119889 246330/7316/3654/7189/6233/7311/7334/7314 8 West_Nile_virus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 8/1715 15/10654 9.824497456425829e-4 0.0023890567615441408 0.0010513299861119889 246330/7316/3654/7189/6233/7311/7334/7314 8 West_Nile_virus R-HSA-201681 TCF dependent signaling in response to WNT 56/1715 233/10654 9.95349585749506e-4 0.002415968239443552 0.0010631726698613509 5718/5689/8945/5684/7015/6597/5682/1499/5525/864/5526/10023/207/1452/5690/5717/5929/79577/1460/10197/7534/8452/5528/55366/7316/10213/9978/1457/4609/5519/5711/1387/5687/5685/5708/5692/5686/2033/5529/5702/5719/6233/5527/7514/4040/7311/79412/5518/8607/6659/5694/5693/5691/7314/5515/5516 56 West_Nile_virus R-HSA-6784531 tRNA processing in the nucleus 19/1715 57/10654 0.001022869476418711 0.0024782021505879797 0.0010905593682405375 60528/23165/4928/81929/55706/7175/9631/29894/79023/57122/10978/1478/11260/9688/10898/8086/1653/6396/51493 19 West_Nile_virus R-HSA-5205647 Mitophagy 12/1715 29/10654 0.0010302076654981663 0.0024914012901405195 0.0010963677908053882 65018/8878/1460/7316/1457/6714/56993/55669/6233/9804/7311/7314 12 West_Nile_virus R-HSA-2029481 FCGR activation 7/1715 12/10654 0.0010349270110234653 0.002493663255080306 0.0010973631926757036 2209/3055/6850/6714/4067/2534/7525 7 West_Nile_virus R-HSA-3371511 HSF1 activation 7/1715 12/10654 0.0010349270110234653 0.002493663255080306 0.0010973631926757036 6118/7531/1915/6119/3320/3326/6117 7 West_Nile_virus R-HSA-193704 p75 NTR receptor-mediated signalling 28/1715 97/10654 0.0010586587510180393 0.0025461902077404666 0.0011204782401285818 4804/445328/4790/5584/10018/7531/57580/835/8878/7074/9459/4615/7316/5970/836/3654/7189/6654/6233/7311/26084/387/6655/5599/5924/5663/7314/5879 28 West_Nile_virus R-HSA-1660499 Synthesis of PIPs at the plasma membrane 18/1715 53/10654 0.0010760023165445323 0.002583189532250808 0.0011367601886991415 5295/5305/5290/5291/59339/22874/8503/146850/4534/5294/5728/59338/51552/5293/5296/8394/375/54477 18 West_Nile_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 13/1715 33/10654 0.0011123977526424442 0.0026657095236049845 0.0011730739936956685 351/4790/7316/5970/177/3146/3656/3654/7189/6233/7311/7334/7314 13 West_Nile_virus R-HSA-9012852 Signaling by NOTCH3 17/1715 49/10654 0.0011205277837143769 0.0026803187276507236 0.00117950293022566 23286/23462/4904/7316/1950/102/6772/22938/8850/1387/2033/6233/7311/1956/4851/5663/7314 17 West_Nile_virus R-HSA-5689603 UCH proteinases 29/1715 102/10654 0.0011324793761399142 0.002703999669841317 0.0011899239821759968 5718/5689/5684/5682/4738/5690/5717/10197/86/580/7316/10213/283899/5711/5687/5685/5708/5692/5686/5702/5719/6233/7311/60/8607/5694/5693/5691/7314 29 West_Nile_virus R-HSA-389357 CD28 dependent PI3K/Akt signaling 10/1715 22/10654 0.0011363182635488677 0.002708259441875963 0.0011917985404310005 5295/5290/207/8503/2534/79109/2475/3932/5296/253260 10 West_Nile_virus R-HSA-5696400 Dual Incision in GG-NER 15/1715 41/10654 0.0011658412645549259 0.002773607918201069 0.001220555836537648 6118/8450/7316/9978/5426/6119/5427/5985/2068/2071/6233/7311/6117/7314/8451 15 West_Nile_virus R-HSA-2500257 Resolution of Sister Chromatid Cohesion 34/1715 126/10654 0.001226935109856652 0.0029136945491730942 0.0012822024571474923 5905/4928/81929/55143/5525/1783/5526/9212/79023/9133/10381/57122/64105/6232/332/5528/5501/983/5519/8243/9126/5529/11004/5527/7514/9184/5518/5347/113130/6396/25909/140735/5515/5516 34 West_Nile_virus R-HSA-5688426 Deubiquitination 68/1715 297/10654 0.0012422728434379779 0.002944812243977077 0.0012958961316439338 5718/5689/23032/5684/51651/5682/7321/4738/7375/5690/57506/91833/5717/409/1080/3091/4287/10197/7706/86/580/7316/10213/79155/890/9986/983/2099/4609/23586/4089/283899/8850/5711/5687/5685/5708/5692/5686/2033/408/64135/5728/8724/5702/7157/63891/5719/84749/7189/6233/672/100287478/9804/7311/78990/387/60/8607/1540/5694/100287404/5693/154/5691/100287205/7314/4193 68 West_Nile_virus R-HSA-5685942 HDR through Homologous Recombination (HRR) 21/1715 67/10654 0.0013971119703038149 0.003305913064381379 0.0014548024107292866 6118/5888/7486/545/580/7316/5426/10635/7517/6119/4683/5427/5985/1111/6233/672/7311/6117/5810/348654/7314 21 West_Nile_virus R-HSA-110320 Translesion Synthesis by POLH 9/1715 19/10654 0.0014057936961537375 0.003314554725457292 0.0014586052661344684 6118/7316/6119/5985/25898/6233/7311/6117/7314 9 West_Nile_virus R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 9/1715 19/10654 0.0014057936961537375 0.003314554725457292 0.0014586052661344684 7321/8697/8881/51529/64682/29945/10393/29882/996 9 West_Nile_virus R-HSA-4791275 Signaling by WNT in cancer 13/1715 34/10654 0.0015389341289797943 0.0036219913964203017 0.0015938960621576443 1499/5525/5526/1452/5528/5519/5529/5527/4040/79412/5518/5515/5516 13 West_Nile_virus R-HSA-168253 Host Interactions with Influenza Factors 15/1715 42/10654 0.0015475009266496561 0.003629192564633891 0.0015970650132683287 23165/4928/3838/81929/55706/7175/9631/8106/9636/79023/57122/9688/10898/8086/6396 15 West_Nile_virus R-HSA-2426168 Activation of gene expression by SREBF (SREBP) 15/1715 42/10654 0.0015475009266496561 0.003629192564633891 0.0015970650132683287 79718/6319/9453/3156/4597/1387/1717/1595/4801/10498/6309/2224/4520/31/10654 15 West_Nile_virus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 14/1715 38/10654 0.0015615153005623858 0.0036555544691673613 0.001608665851378657 3815/7422/4869/4839/2064/1026/2099/4609/3329/1387/2033/7329/1956/10765 14 West_Nile_virus R-HSA-351202 Metabolism of polyamines 19/1715 59/10654 0.0016272412689570732 0.0038026666533429476 0.001673404141835288 5718/5689/5684/5682/5690/5717/10197/10213/5711/5687/5685/5708/5692/5686/5702/5719/5694/5693/5691 19 West_Nile_virus R-HSA-110312 Translesion synthesis by REV1 8/1715 16/10654 0.0016890964551200202 0.003933267010332486 0.0017308762260947205 6118/7316/6119/5985/6233/7311/6117/7314 8 West_Nile_virus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 8/1715 16/10654 0.0016890964551200202 0.003933267010332486 0.0017308762260947205 7099/7316/929/3656/7189/6233/7311/7314 8 West_Nile_virus R-HSA-373753 Nephrin family interactions 10/1715 23/10654 0.0017230522731987742 0.004005260839640184 0.001762557880873526 5295/8573/6711/5290/5291/2534/6709/88/8826/5296 10 West_Nile_virus R-HSA-70326 Glucose metabolism 26/1715 91/10654 0.0018464032995985365 0.004284435825476885 0.0018854118200125902 23165/4928/81929/5313/2597/55706/7175/9631/5315/79023/57122/5214/5528/5230/3098/9688/5519/2023/226/2821/8086/5518/4191/6396/5515/5516 26 West_Nile_virus R-HSA-111461 Cytochrome c-mediated apoptotic response 7/1715 13/10654 0.001931770637808858 0.0044746462225519765 0.001969115940121507 842/55075/5594/54205/836/840/5595 7 West_Nile_virus R-HSA-390450 Folding of actin by CCT/TriC 6/1715 10/10654 0.0020128162842117047 0.004629828730525352 0.0020374056629019004 10694/7203/10576/10574/60/22948 6 West_Nile_virus R-HSA-8875656 MET receptor recycling 6/1715 10/10654 0.0020128162842117047 0.004629828730525352 0.0020374056629019004 3082/382/4233/2885/23163/2549 6 West_Nile_virus R-HSA-9020958 Interleukin-21 signaling 6/1715 10/10654 0.0020128162842117047 0.004629828730525352 0.0020374056629019004 3561/6775/6774/3718/6772/3716 6 West_Nile_virus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 6/1715 10/10654 0.0020128162842117047 0.004629828730525352 0.0020374056629019004 7316/3656/7189/6233/7311/7314 6 West_Nile_virus R-HSA-5696395 Formation of Incision Complex in GG-NER 15/1715 43/10654 0.0020282798903588743 0.004657269852775255 0.0020494814223138455 6118/902/8450/7316/9978/6119/2068/2071/7329/6233/7311/6117/7334/7314/8451 15 West_Nile_virus R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 12/1715 31/10654 0.002049202711720984 0.004697128998344795 0.002067021865735949 23165/4928/81929/55706/7175/9631/79023/57122/9688/8086/7514/6396 12 West_Nile_virus R-HSA-6807878 COPI-mediated anterograde transport 28/1715 101/10654 0.002068241665002674 0.004732539087627647 0.0020826044543429704 2348/11070/6711/6712/1783/5861/10381/1604/9570/1315/832/57731/6710/8775/11316/9527/10972/10540/6708/4905/287/6709/51332/375/140735/10959/10652/51164 28 West_Nile_virus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 14/1715 39/10654 0.002080398190705918 0.004752105399220797 0.0020912148190804724 6118/9636/7706/7316/5426/6119/5427/5985/25898/9246/6233/7311/6117/7314 14 West_Nile_virus R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 13/1715 35/10654 0.0020924820991133383 0.004763197593491157 0.0020960960578337417 23165/4928/81929/55706/7175/9631/79023/9133/57122/983/9688/8086/6396 13 West_Nile_virus R-HSA-9615710 Microautophagy 13/1715 35/10654 0.0020924820991133383 0.004763197593491157 0.0020960960578337417 79643/1080/5116/91782/7316/89853/123/6233/7311/200894/93343/3312/7314 13 West_Nile_virus R-HSA-6794361 Neurexins and neuroligins 18/1715 56/10654 0.0021871312464266457 0.0049700672117074475 0.0021871312464266457 8573/2035/2904/2036/2902/23136/22839/57669/9369/55327/2905/2903/2037/9066/1741/2906/1742/1740 18 West_Nile_virus R-HSA-5627117 RHO GTPases Activate ROCKs 9/1715 20/10654 0.002194045718595783 0.004977198377124341 0.0021902693920577525 1072/4627/4637/9475/4628/6093/387/5058/5500 9 Yaba_monkey_tumor_virus R-HSA-449147 Signaling by Interleukins 163/511 461/10654 1.3631712597139845e-103 1.3672607734931265e-100 6.801507127415038e-101 5716/9491/6364/5715/85480/23198/3605/3557/7124/1147/2353/5718/64127/5743/7311/5711/7132/834/3552/5689/1432/941/3725/56300/6347/8945/5701/23118/5688/143471/4318/5706/4312/3567/5687/3383/5705/3558/4067/5684/3562/351/23291/10197/8517/598/836/5720/3576/5685/4615/7040/5683/3687/1437/5698/5708/5692/5686/4790/5713/4843/2335/6885/5599/2534/5600/5606/5682/7334/6356/4313/3600/90865/7316/595/3565/10213/5709/4215/5694/5699/2920/5657/11213/3574/3559/3551/5695/79155/5710/6352/7412/5700/6351/3458/3181/3578/122706/10454/5707/6416/84868/5702/3185/5608/27178/998/6774/3569/7157/1435/5970/4792/3162/3589/5693/6648/6348/9261/207/1234/5721/5696/942/5451/3684/1440/5719/3627/3586/3654/5691/9021/7422/7133/4791/5714/29110/3606/7189/3554/5690/3553/6772/5594/829/5609/8878/4609/7314/5704/6233/3596/5595/7867/5717/59067/257397/9861/2919/3716/84639 163 Yaba_monkey_tumor_virus R-HSA-446652 Interleukin-1 family signaling 88/511 140/10654 4.565726779186876e-82 2.2897119797622185e-079 1.1390286807024101e-79 5716/9491/5715/23198/3557/1147/5718/64127/7311/5711/834/3552/5689/56300/8945/5701/23118/5688/143471/5706/5687/5705/5684/351/23291/10197/8517/5720/5685/4615/5683/5698/5708/5692/5686/4790/5713/6885/5599/5682/7334/90865/7316/3565/10213/5709/4215/5694/5699/11213/3551/5695/79155/5710/5700/122706/10454/5707/6416/5702/5608/27178/6774/5970/4792/5693/5721/5696/5719/3654/5691/4791/5714/29110/3606/7189/3554/5690/3553/8878/7314/5704/6233/3596/5717/257397/9861/84639 88 Yaba_monkey_tumor_virus R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 77/511 102/10654 1.2862904578068825e-81 4.3004977639343435e-79 2.1393041298261833e-79 5716/9491/5715/23198/8792/7124/1147/5718/330/7311/5711/7132/5971/5689/8945/7293/5701/5688/143471/329/5706/8764/5687/115650/5705/4050/7187/5684/8744/23291/10197/10673/5720/5685/5683/5698/5708/7186/5692/5686/5713/51330/958/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/9020/5702/3604/5693/5721/8742/5696/5719/5691/8600/7133/4791/5714/5690/4049/959/8740/7314/5704/6233/4055/5717/9861 77 Yaba_monkey_tumor_virus R-HSA-9020702 Interleukin-1 signaling 77/511 103/10654 4.888835200294993e-81 1.2258754264739695e-78 6.098178644578491e-79 5716/9491/5715/23198/3557/1147/5718/64127/7311/5711/3552/5689/8945/5701/23118/5688/143471/5706/5687/5705/5684/351/23291/10197/8517/5720/5685/4615/5683/5698/5708/5692/5686/4790/5713/6885/5682/7334/7316/10213/5709/4215/5694/5699/11213/3551/5695/79155/5710/5700/122706/10454/5707/6416/5702/5608/5970/4792/5693/5721/5696/5719/3654/5691/4791/5714/7189/3554/5690/3553/8878/7314/5704/6233/5717/257397/9861 77 Yaba_monkey_tumor_virus R-HSA-9010553 Regulation of expression of SLITs and ROBOs 91/511 171/10654 1.358100496457205e-75 2.7243495958931532e-73 1.3552413375172953e-73 5716/9491/5715/23198/6158/5718/7311/5711/6204/6223/5689/6224/6146/51065/6154/6138/5701/26986/5688/143471/6202/6228/5706/23521/5687/5705/5684/9349/4736/10197/5720/6188/5685/6232/1605/6206/6194/5683/5698/5708/5692/5686/5713/6191/6128/6135/6164/5682/7316/6155/10213/5709/5694/5699/6235/6129/6218/5695/5710/5700/6181/122706/5707/6124/5702/6207/5693/6222/5721/6137/5696/6176/6170/5719/5691/5714/6139/5690/6136/6122/6133/6229/6231/7314/5704/6233/6125/5717/9861/6230/6130 91 Yaba_monkey_tumor_virus R-HSA-5607764 CLEC7A (Dectin-1) signaling 72/511 101/10654 3.65095723702594e-73 6.103183514561697e-71 3.0360591760531505e-71 5716/9491/5715/23198/1147/5718/7311/5711/5971/5689/8945/5701/23118/5688/143471/5706/5687/5705/5684/23291/841/10197/8517/5720/5685/5683/5698/5708/808/5692/5686/4790/5713/6885/5682/7334/7316/10213/5709/5694/5699/3551/5695/64581/5710/801/4772/5700/122706/10454/5707/9020/5702/5970/4792/5693/5721/5696/5719/5691/4791/5714/7189/5690/3553/7314/5704/6233/805/5717/257397/9861 72 Yaba_monkey_tumor_virus R-HSA-376176 Signaling by ROBO receptors 96/511 218/10654 9.597470403793231e-70 1.3751804021435158e-67 6.840903716387958e-68 5716/9491/5715/23198/6158/5718/7311/5711/6204/6223/5689/6224/6146/51065/6154/6138/5701/26986/5688/143471/6202/6228/5706/23521/5687/5705/5684/9349/4736/10197/7852/5720/6188/5685/6232/1605/6206/6194/5683/5698/5708/5692/8829/5686/5713/6191/6128/6135/6164/5682/7316/6155/10213/5709/5694/5699/6235/6129/6218/5695/5710/5700/6181/122706/5707/6124/5702/998/6207/5693/6222/5721/6137/5696/6176/6170/5719/5691/5714/6139/5690/6136/6122/6133/6229/6231/7314/5879/5704/6233/6125/5717/9861/6387/6230/6130 96 Yaba_monkey_tumor_virus R-HSA-1169091 Activation of NF-kappaB in B cells 58/511 67/10654 3.6523432438510136e-68 4.579125341978208e-66 2.2779088126123427e-66 5716/9491/5715/23198/1147/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/23291/10197/8517/5720/5685/5683/5698/5708/5692/5686/4790/5713/6885/5966/5682/7316/10213/5709/5694/5699/3551/5695/5710/5700/122706/5707/5702/5970/4792/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 58 Yaba_monkey_tumor_virus R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 55/511 60/10654 6.992331248763154e-68 7.792564713899382e-66 3.876450306331854e-66 5716/9491/5715/23198/1147/5718/7311/5711/5971/5689/8945/5701/5688/143471/5706/5687/5705/5684/23291/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/9020/5702/5970/5693/5721/5696/5719/5691/4791/5714/5690/7314/5704/6233/5717/9861 55 Yaba_monkey_tumor_virus R-HSA-2871837 FCERI mediated NF-kB activation 63/511 82/10654 1.5434352543190794e-67 1.5480655600820366e-65 7.700929584707828e-66 5716/9491/5715/23198/1147/5718/7311/5711/5689/8945/5701/23118/5688/143471/5706/5687/5705/4067/5684/23291/10197/8517/5720/5685/5683/5698/5708/5692/5686/4790/5713/6885/5682/7334/7316/10213/5709/5694/5699/3551/5695/5710/5700/122706/10454/5707/5702/5970/4792/5693/5721/5696/5719/5691/5714/7189/5690/7314/5704/6233/5717/257397/9861 63 Yaba_monkey_tumor_virus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 77/511 134/10654 2.7045966728123372e-67 2.4661004207552494e-65 1.2267739932182274e-65 5716/9491/5715/23198/1147/2353/5718/7311/5711/5689/3725/8945/5701/23118/5688/143471/5706/5687/5705/4067/5684/23291/10197/8517/5720/5685/5683/5698/5708/808/5692/5686/4790/5713/6885/5599/2534/5682/7334/7316/10213/5709/5694/5699/3551/5695/5710/801/4772/5700/122706/10454/5707/6416/5702/5970/4792/5693/5721/5696/5719/5691/5714/7189/5690/5594/5609/7314/5879/5704/6233/5595/805/5717/257397/9861/4214 77 Yaba_monkey_tumor_virus R-HSA-5676590 NIK-->noncanonical NF-kB signaling 54/511 59/10654 1.4861199925278127e-66 1.24214862708783e-64 6.1791304952472215e-65 5716/9491/5715/23198/1147/5718/7311/5711/5971/5689/8945/5701/5688/143471/5706/5687/5705/5684/23291/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/9020/5702/5693/5721/5696/5719/5691/4791/5714/5690/7314/5704/6233/5717/9861 54 Yaba_monkey_tumor_virus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 62/511 83/10654 4.155669079620366e-65 3.206258528353252e-63 1.5949693471579382e-63 5716/9491/5715/23198/1147/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/23291/10197/8517/5720/5685/5683/5698/5708/808/5692/5686/4790/5713/6885/5966/5682/7316/10213/5709/5694/5699/3551/5695/5710/801/4772/5700/122706/5707/5702/5970/4792/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/805/5717/9861 62 Yaba_monkey_tumor_virus R-HSA-5621481 C-type lectin receptors (CLRs) 77/511 142/10654 1.2888643002039612e-64 9.233792093604093e-63 4.5933960774186285e-63 5716/9491/5715/23198/1147/5718/7311/5711/5971/5689/8945/5701/23118/5688/1387/143471/5706/5687/5705/4586/4067/5684/23291/841/10197/8517/5720/5685/5683/5698/5708/808/5692/5686/4790/5713/6885/2534/2033/5682/7334/7316/10213/5709/5694/5699/3551/5695/64581/5710/801/4772/5700/122706/10454/5707/9020/5702/5970/4792/5693/5721/5696/5719/5691/4791/5714/7189/5690/3553/7314/5704/6233/805/5717/257397/9861 77 Yaba_monkey_tumor_virus R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 51/511 56/10654 1.395725732210537e-62 9.332752729381124e-61 4.642624540826629e-61 5716/9491/5715/3315/23198/5718/7311/5711/5689/5701/26986/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/3184/5717/9861 51 Yaba_monkey_tumor_virus R-HSA-180534 Vpu mediated degradation of CD4 49/511 52/10654 4.649112159716536e-62 2.590588608997603e-60 1.2887012653249344e-60 5716/9491/5715/23198/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Yaba_monkey_tumor_virus R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 49/511 52/10654 4.649112159716536e-62 2.590588608997603e-60 1.2887012653249344e-60 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/7157/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Yaba_monkey_tumor_virus R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 49/511 52/10654 4.649112159716536e-62 2.590588608997603e-60 1.2887012653249344e-60 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/595/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Yaba_monkey_tumor_virus R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 48/511 50/10654 6.165554578321776e-62 3.2547638116088113e-60 1.6190985430052752e-60 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 48/511 52/10654 1.2485204421556095e-59 5.692118197645802e-58 2.8315726774246836e-58 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-69610 p53-Independent DNA Damage Response 48/511 52/10654 1.2485204421556095e-59 5.692118197645802e-58 2.8315726774246836e-58 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 48/511 52/10654 1.2485204421556095e-59 5.692118197645802e-58 2.8315726774246836e-58 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 49/511 55/10654 5.350044486112564e-59 2.3330846172047399e-57 1.1606046162093159e-57 5716/9491/5715/23198/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Yaba_monkey_tumor_virus R-HSA-169911 Regulation of Apoptosis 48/511 53/10654 1.2668202538208224e-58 5.294252977426187e-57 2.6336526329432886e-57 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-5663205 Infectious disease 111/511 383/10654 2.6307717572552524e-058 1.0554656290108073e-56 5.250466580795746e-57 5716/9491/5715/23198/6158/163/5718/7311/5711/6204/6223/5689/6224/6146/51065/6154/6138/8945/5701/5688/143471/6202/6228/5706/23521/5687/1213/5705/5684/9349/4736/10197/7852/5720/6188/5685/6232/6206/6194/7040/5683/5698/5708/8815/808/5692/5686/5713/6191/2534/6128/6135/6164/5606/5682/7316/6155/1938/10213/5709/5694/5699/1175/6235/6129/6218/5695/5710/801/5700/6181/122706/5707/6416/6124/5702/5608/292/6207/5693/6222/1234/5721/6137/5696/6176/6170/5719/5691/5714/6139/5690/6136/6122/6133/5605/5609/6229/6231/940/7314/5879/5704/6233/805/6125/5717/9861/4869/6230/6130 111 Yaba_monkey_tumor_virus R-HSA-180585 Vif-mediated degradation of APOBEC3G 48/511 54/10654 1.0913638267465038e-57 4.054214511950901e-56 2.0167892938707322e-56 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 48/511 54/10654 1.0913638267465038e-57 4.054214511950901e-56 2.0167892938707322e-56 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-69541 Stabilization of p53 49/511 57/10654 2.79457588181721e-57 1.001057003379522e-55 4.979808150305856e-56 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/7157/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Yaba_monkey_tumor_virus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 65/511 112/10654 3.951545656573504e-57 1.3666897563942153e-55 6.798666574286174e-56 5716/9491/5715/23198/930/1147/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/4067/5684/23291/10197/8517/5720/5685/5683/5698/5708/808/5692/5686/4790/5713/6885/2534/5966/5682/7316/10213/5709/5694/5699/3551/5695/5710/801/4772/5700/122706/5707/5702/5970/4792/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/805/5717/9861 65 Yaba_monkey_tumor_virus R-HSA-4641257 Degradation of AXIN 48/511 55/10654 8.208141302531965e-57 2.74425524214652e-55 1.3651435008421584e-55 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-1236974 ER-Phagosome pathway 57/511 83/10654 2.312550644208685e-56 7.48222031013326e-55 3.722067929897849e-55 5716/9491/5715/23198/1147/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10333/10197/7099/8517/5720/5685/4615/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/7097/5699/3551/5695/29927/5710/5700/122706/5707/5702/7096/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 57 Yaba_monkey_tumor_virus R-HSA-202424 Downstream TCR signaling 61/511 98/10654 2.707659736667359e-56 8.486820987116754e-55 4.221811563093185e-55 5716/9491/5715/23198/1147/5718/7311/5711/5689/8945/5701/23118/5688/143471/5706/5687/5705/5684/23291/10197/8517/5720/5685/5683/5698/5708/5692/5686/4790/5713/6885/5682/7334/7316/10213/5728/5709/5694/5699/3551/5695/5710/5700/122706/5707/5702/5970/4792/5693/5721/5696/5719/5691/5714/7189/5690/7314/5704/6233/5717/9861 61 Yaba_monkey_tumor_virus R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 48/511 56/10654 5.499865346406701e-56 1.6716257401351277e-54 8.315585882605347e-55 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-75893 TNF signaling 42/511 43/10654 3.1273791714200322e-55 9.225768555689094e-54 4.589404728337756e-54 7124/1147/330/7128/7311/25999/6610/7132/90268/23118/329/81858/84888/9099/841/27005/8517/8772/10616/331/7186/56957/6885/8717/8887/7316/1540/3551/56928/7185/10454/8737/55512/8567/55072/8439/7375/6868/9530/7314/6233/257397 42 Yaba_monkey_tumor_virus R-HSA-4641258 Degradation of DVL 48/511 57/10654 3.3342040056940466e-55 9.554876050603226e-54 4.753120898342791e-54 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-5610780 Degradation of GLI1 by the proteasome 49/511 60/10654 5.08424714038803e-55 1.3419736531076826e-53 6.67571508183913e-54 5716/9491/5715/23198/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Yaba_monkey_tumor_virus R-HSA-5610783 Degradation of GLI2 by the proteasome 49/511 60/10654 5.08424714038803e-55 1.3419736531076826e-53 6.67571508183913e-54 5716/9491/5715/23198/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Yaba_monkey_tumor_virus R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 49/511 60/10654 5.08424714038803e-55 1.3419736531076826e-53 6.67571508183913e-54 5716/9491/5715/23198/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Yaba_monkey_tumor_virus R-HSA-8941858 Regulation of RUNX3 expression and activity 47/511 55/10654 1.0770284826820808e-54 2.7698963285387874e-53 1.3778987875608808e-53 5716/9491/5715/5718/7311/5711/5689/5701/5688/5706/5687/5705/5684/10197/5720/5685/7040/5683/5698/5708/5692/5686/5713/2033/5682/7316/10213/5709/5694/5699/5695/5710/5700/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 47 Yaba_monkey_tumor_virus R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 45/511 50/10654 1.1092726373629742e-54 2.7815011381876576e-53 1.3836716581843415e-53 5716/9491/5715/23198/5718/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/5704/4360/5717/9861 45 Yaba_monkey_tumor_virus R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 57/511 88/10654 4.2980077689517364e-54 1.0514394615264858e-52 5.230438209199289e-53 5716/9491/5715/3315/23198/5718/7311/5711/5689/1432/5701/26986/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/7538/5600/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/9261/207/5721/5696/5719/5691/5714/5690/7314/5704/6233/3184/1994/5717/9861 57 Yaba_monkey_tumor_virus R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 45/511 51/10654 9.023516815219791e-54 2.154901753729869e-52 1.0719666592516744e-52 5716/9491/5715/23198/5718/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/1728/5720/5685/5683/5698/5708/5692/5686/5713/5682/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/5704/5717/9861 45 Yaba_monkey_tumor_virus R-HSA-5387390 Hh mutants abrogate ligand secretion 48/511 59/10654 9.503656765996673e-54 2.166401758248787e-52 1.0776873940388571e-52 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 48/511 59/10654 9.503656765996673e-54 2.166401758248787e-52 1.0776873940388571e-52 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-9604323 Negative regulation of NOTCH4 signaling 46/511 54/10654 2.0984251376697306e-53 4.6771564735171994e-52 2.326674889486438e-52 5716/9491/5715/5718/7311/5711/5689/5701/5688/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/5707/5702/5693/207/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 46 Yaba_monkey_tumor_virus R-HSA-8948751 Regulation of PTEN stability and activity 51/511 69/10654 3.5758600135685135e-53 7.79692955132439e-52 3.878621616547999e-52 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/331/5698/5708/5692/5686/5713/5682/7316/10213/5728/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/207/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 51 Yaba_monkey_tumor_virus R-HSA-5357801 Programmed Cell Death 76/511 181/10654 4.649251471247244e-53 9.921700480129756e-52 4.9355995461840845e-52 5716/9491/5715/23198/4000/355/5718/330/7311/5711/5689/5701/5688/143471/329/5706/5687/5705/5684/841/10197/7099/598/8772/836/5720/5685/5683/331/5698/5708/7186/5692/5686/5713/5599/8717/5682/8837/7316/10213/5709/5694/5699/5695/842/5710/637/5700/8743/3002/122706/5707/8655/5702/8737/7082/6774/7157/5693/207/5721/10971/5696/5339/5719/5691/5714/5690/5594/7314/5704/6233/5595/5717/9861 76 Yaba_monkey_tumor_virus R-HSA-1236975 Antigen processing-Cross presentation 59/511 99/10654 7.962457085716236e-53 1.663821761869455e-51 8.276764602257666e-52 4012/5716/9491/5715/23198/1147/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10333/10197/7099/8517/5720/5685/4615/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/7097/5699/3551/5695/29927/5710/5700/122706/5707/5702/7096/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/4360/5717/9861 59 Yaba_monkey_tumor_virus R-HSA-109581 Apoptosis 75/511 178/10654 1.7300387268592918e-52 3.541283353142591e-51 1.7616291225162283e-51 5716/9491/5715/23198/4000/355/5718/7311/5711/5689/5701/5688/143471/329/5706/5687/5705/5684/841/10197/7099/598/8772/836/5720/5685/5683/331/5698/5708/7186/5692/5686/5713/5599/8717/5682/8837/7316/10213/5709/5694/5699/5695/842/5710/637/5700/8743/3002/122706/5707/8655/5702/8737/7082/6774/7157/5693/207/5721/10971/5696/5339/5719/5691/5714/5690/5594/7314/5704/6233/5595/5717/9861 75 Yaba_monkey_tumor_virus R-HSA-5678895 Defective CFTR causes cystic fibrosis 48/511 61/10654 2.0429266952395e-52 4.098110950650437e-51 2.0386257969337324e-51 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-5687128 MAPK6/MAPK4 signaling 56/511 89/10654 4.400401767474324e-52 8.654123476032837e-51 4.305037023287574e-51 5716/9491/5715/3315/23198/5718/7311/5711/5689/27161/3725/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/10642/122706/5707/5702/998/5693/5721/5696/5719/5691/5714/5690/23112/4609/7314/5879/5704/6233/5717/9861 56 Yaba_monkey_tumor_virus R-HSA-5358346 Hedgehog ligand biogenesis 49/511 65/10654 7.728239129237962e-52 1.4906584320433993e-50 7.41535495396517e-51 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/6868/5690/7314/5704/6233/5717/9861 49 Yaba_monkey_tumor_virus R-HSA-69563 p53-Dependent G1 DNA Damage Response 49/511 66/10654 2.8721275846135124e-51 5.334711050680283e-50 2.6537787039119007e-50 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/7157/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Yaba_monkey_tumor_virus R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 49/511 66/10654 2.8721275846135124e-51 5.334711050680283e-50 2.6537787039119007e-50 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/7157/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Yaba_monkey_tumor_virus R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 52/511 77/10654 7.716696670927563e-51 1.4072448656255175e-49 7.000409994296009e-50 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/10383/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/10376/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/7157/5693/5721/5696/5719/5691/5714/5690/10382/7314/5704/6233/5717/9861 52 Yaba_monkey_tumor_virus R-HSA-4608870 Asymmetric localization of PCP proteins 48/511 64/10654 1.332979190933131e-50 2.3874609437605898e-49 1.1876543919216242e-49 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-202403 TCR signaling 62/511 119/10654 1.588440414351567e-50 2.7950977817449503e-49 1.3904353765515102e-49 5716/9491/5715/23198/1147/5718/7311/5711/5689/8945/5701/23118/5688/143471/5706/5687/5705/5684/23291/5788/10197/8517/5720/5685/5683/5698/5708/5692/5686/4790/5713/6885/5682/7334/7316/10213/5728/5709/5694/5699/3551/5695/5710/5700/122706/5707/5702/5970/4792/5693/5721/5696/5719/5691/5714/7189/5690/7314/5704/6233/5717/9861 62 Yaba_monkey_tumor_virus R-HSA-69615 G1/S DNA Damage Checkpoints 49/511 68/10654 3.5060116424272925e-50 6.0629822023354725e-49 3.0160608321425348e-49 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/7157/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Yaba_monkey_tumor_virus R-HSA-1234174 Cellular response to hypoxia 51/511 75/10654 4.1194397854430356e-50 7.00304763525316e-49 3.4837010852809965e-49 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/1387/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/2033/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/7422/5714/5690/7314/5704/6233/5717/9861 51 Yaba_monkey_tumor_virus R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 48/511 66/10654 1.712184477968772e-49 2.8622017190044637e-48 1.423816565889821e-48 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-8939902 Regulation of RUNX2 expression and activity 50/511 73/10654 2.17903233759133e-49 3.582900712465744e-48 1.7823318861402772e-48 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/2908/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/6772/7314/5704/6233/5717/9861 50 Yaba_monkey_tumor_virus R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 46/511 60/10654 2.6885146231438424e-49 4.349322850021409e-48 2.1635924131921584e-48 5716/9491/5715/5718/7311/5711/5689/5701/5688/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/595/10213/5709/5694/5699/5695/5710/5700/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 46 Yaba_monkey_tumor_virus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 48/511 67/10654 5.7791675383925716e-49 9.200801652393252e-48 4.5769848173735655e-48 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-5658442 Regulation of RAS by GAPs 48/511 68/10654 1.880772683635282e-48 2.9021769256710584e-47 1.4437024324585e-47 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-68867 Assembly of the pre-replicative complex 48/511 68/10654 1.880772683635282e-48 2.9021769256710584e-47 1.4437024324585e-47 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-351202 Metabolism of polyamines 45/511 59/10654 4.687893633589688e-48 7.124177749227966e-47 3.543957866541487e-47 5716/9491/5715/23198/5718/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/1728/5720/5685/5683/5698/5708/5692/5686/5713/5682/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/5704/5717/9861 45 Yaba_monkey_tumor_virus R-HSA-68949 Orc1 removal from chromatin 48/511 71/10654 5.322795430216891e-47 7.968304203742599e-46 3.963872794851228e-46 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 48/511 72/10654 1.5284367027012143e-46 2.1900314468704542e-45 1.0894421008727452e-45 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 48/511 72/10654 1.5284367027012143e-46 2.1900314468704542e-45 1.0894421008727452e-45 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 48/511 72/10654 1.5284367027012143e-46 2.1900314468704542e-45 1.0894421008727452e-45 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 48/511 73/10654 4.2718433536684756e-46 6.034730822154198e-45 3.0020070417180984e-45 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-5619084 ABC transporter disorders 49/511 77/10654 5.525713667494719e-46 7.697626122912782e-45 3.8292226292287966e-45 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/10058/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Yaba_monkey_tumor_virus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 45/511 63/10654 7.653762884543147e-46 1.0516060511228461e-44 5.231266917481546e-45 5716/9491/5715/5718/7311/5711/5689/5701/5688/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 45 Yaba_monkey_tumor_virus R-HSA-9013694 Signaling by NOTCH4 50/511 82/10654 1.537070822309577e-45 2.083354101049332e-44 1.0363749214434415e-44 2324/5716/9491/5715/5718/7311/5711/5689/5701/5688/1387/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/2033/5682/7316/10213/5709/5694/5699/5695/5710/5700/5707/5702/4851/5693/207/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Yaba_monkey_tumor_virus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 48/511 75/10654 3.0941185977323046e-45 4.137867938034002e-44 2.0584031092282276e-44 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-8878159 Transcriptional regulation by RUNX3 53/511 96/10654 5.0670647905679054e-45 6.687192085446854e-44 3.3265771616747744e-44 5716/9491/5715/5718/7311/5711/5689/5701/5688/1387/5706/5687/5705/5684/10197/5720/5685/7040/5683/5698/5708/5692/5686/5713/2033/5682/7316/595/10213/5709/5694/5699/5695/5710/5700/5707/5702/4851/7157/5693/5721/5696/5719/5691/5714/5690/3676/4609/7314/5704/6233/5717/9861 53 Yaba_monkey_tumor_virus R-HSA-4086400 PCP/CE pathway 52/511 92/10654 6.54354954382704e-45 8.523610639556522e-44 4.240112759773092e-44 5716/9491/5715/23198/163/5718/7311/5711/5689/5701/5688/143471/5706/5687/1213/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/1175/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5879/5704/6233/5717/9861 52 Yaba_monkey_tumor_virus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 48/511 76/10654 8.038467772616804e-45 1.0336645097352121e-43 5.142015822159737e-44 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 49/511 80/10654 8.858245274693268e-45 1.1246607608249807e-43 5.594681226122063e-44 5716/9491/5715/23198/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Yaba_monkey_tumor_virus R-HSA-195253 Degradation of beta-catenin by the destruction complex 49/511 82/10654 5.104986133332345e-44 6.4003763646654275e-43 3.1838992463151734e-43 5716/9491/5715/23198/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Yaba_monkey_tumor_virus R-HSA-8878166 Transcriptional regulation by RUNX2 57/511 121/10654 2.9235344077576868e-43 3.6201296431863705e-42 1.8008516039988868e-42 5716/9491/5715/23198/5718/8493/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/8841/4322/5720/2908/5685/5683/5698/5708/5692/5686/5713/5682/7316/595/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/207/5721/5696/5719/5691/5714/5690/6772/5594/7314/5704/6233/5595/5717/9861 57 Yaba_monkey_tumor_virus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 49/511 86/10654 1.3779226056765854e-42 1.6651281608356807e-41 8.283263349279662e-42 5716/9491/5715/23198/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Yaba_monkey_tumor_virus R-HSA-453276 Regulation of mitotic cell cycle 49/511 86/10654 1.3779226056765854e-42 1.6651281608356807e-41 8.283263349279662e-42 5716/9491/5715/23198/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Yaba_monkey_tumor_virus R-HSA-6807070 PTEN Regulation 60/511 140/10654 1.6734610182281305e-42 1.9981921443843034e-41 9.940106800001677e-42 5716/9491/5715/23198/5718/7311/5711/5689/27161/3725/5701/5688/143471/5706/5687/5705/5684/10197/8841/5720/5685/5683/331/5698/5708/5692/5686/5713/5682/7316/10213/5728/5709/5468/5694/5699/6009/5695/5710/5700/122706/5707/5702/7157/5693/207/5721/5696/5719/5691/5714/5690/23112/5594/7314/5704/6233/5595/5717/9861 60 Yaba_monkey_tumor_virus R-HSA-69202 Cyclin E associated events during G1/S transition 48/511 83/10654 3.652468690102872e-42 4.3099130543213893e-41 2.1439878131377852e-41 5716/9491/5715/5718/7311/5711/5689/5701/5688/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/595/10213/5709/5694/5699/5695/5710/5700/5707/5702/5693/207/5721/5696/5719/5691/5714/5690/4609/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-5357905 Regulation of TNFR1 signaling 32/511 33/10654 7.549378614855903e-42 8.804682268256362e-41 4.379933247786656e-41 7124/1147/330/7128/7311/25999/7132/90268/329/81858/84888/9099/841/27005/8517/10616/331/7186/56957/8717/8887/7316/1540/3551/56928/7185/8737/8567/55072/7375/7314/6233 32 Yaba_monkey_tumor_virus R-HSA-71291 Metabolism of amino acids and derivatives 92/511 372/10654 1.3876156890389546e-41 1.599745443800082e-40 7.958013752020138e-41 5716/9491/5715/23198/6158/5718/7311/5711/6204/6223/5689/6224/6146/51065/6154/6138/5701/5688/143471/6202/6228/5706/23521/5687/5705/5684/9349/4736/10197/1728/5720/6188/5685/6232/6206/6194/5683/5698/5708/5692/5686/5713/6191/6128/6135/6164/5682/6155/10213/5709/5694/5699/6235/6129/6218/3620/5695/5710/5700/6181/122706/5707/6124/5702/2744/6207/5693/6222/5721/6137/5696/6176/6170/5719/5691/2875/5714/383/6139/5690/6136/6122/6133/6229/6231/5704/6233/6125/5717/9861/6230/6130 92 Yaba_monkey_tumor_virus R-HSA-5632684 Hedgehog 'on' state 48/511 85/10654 1.7935684881613324e-41 1.998832437362018e-40 9.943291969455806e-41 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-69002 DNA Replication Pre-Initiation 48/511 85/10654 1.7935684881613324e-41 1.998832437362018e-40 9.943291969455806e-41 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 48/511 85/10654 1.7935684881613324e-41 1.998832437362018e-40 9.943291969455806e-41 5716/9491/5715/5718/7311/5711/5689/5701/5688/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/595/10213/5709/5694/5699/5695/5710/5700/5707/5702/5693/207/5721/5696/5719/5691/5714/5690/4609/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-162909 Host Interactions of HIV factors 57/511 129/10654 2.6340894909338204e-41 2.9032876476995844e-40 1.4442549666889888e-40 5716/9491/5715/23198/163/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/8815/5692/5686/5713/2534/5682/7316/10213/5709/5694/5699/1175/5695/5710/5700/122706/5707/5702/292/5693/5721/5696/5719/5691/5714/5690/940/7314/5879/5704/6233/5717/9861/4869 57 Yaba_monkey_tumor_virus R-HSA-1257604 PIP3 activates AKT signaling 77/511 264/10654 3.0472635874558954e-40 3.322179758932895e-39 1.652634943311321e-39 5716/9491/5715/23198/930/1147/5718/7311/5711/5689/27161/941/3725/5701/5688/143471/5706/5687/5705/5684/1956/10197/8841/5720/5685/4615/29851/5683/331/5698/5708/5692/5686/5713/2534/5682/90865/7316/10213/5728/5709/5468/5694/5699/6009/1950/5695/842/5710/5700/122706/5707/3630/5702/8870/7157/5693/207/5721/5696/942/5719/3654/5691/5714/7189/5690/23112/5594/940/7314/5879/5704/6233/5595/5717/9861 77 Yaba_monkey_tumor_virus R-HSA-3858494 Beta-catenin independent WNT signaling 59/511 146/10654 5.124018614088202e-40 5.526226526806953e-39 2.7490490357417178e-39 5716/9491/5715/23198/163/5718/7311/5711/5689/27161/5701/5688/143471/5706/5687/1213/5705/5684/10197/5720/5685/5683/5698/5708/808/5692/5686/5713/6885/5682/7316/10213/5709/5694/5699/1175/5695/5710/801/4772/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/23112/7314/5879/5704/6233/805/5717/9861 59 Yaba_monkey_tumor_virus R-HSA-73887 Death Receptor Signalling 58/511 141/10654 7.204664747634595e-40 7.687530576465424e-39 3.824200549136392e-39 7124/355/1147/330/7128/7311/25999/6610/7132/90268/23118/329/81858/84888/9099/841/27005/8841/8517/8772/836/4615/10616/331/7186/56957/4790/6885/5599/8717/8887/8837/7316/5584/1540/3551/56928/7185/8743/10454/8737/55512/8567/5970/4792/55072/8439/3654/7189/7375/6868/835/9530/8878/7314/5879/6233/257397 58 Yaba_monkey_tumor_virus R-HSA-69052 Switching of origins to a post-replicative state 48/511 90/10654 7.442665852278672e-40 7.857888262984745e-39 3.908945832664921e-39 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-5689603 UCH proteinases 50/511 102/10654 4.232394475642395e-39 4.4219704781972104e-38 2.1997313393141393e-38 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/60/5720/5685/7040/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Yaba_monkey_tumor_virus R-HSA-5610787 Hedgehog 'off' state 52/511 113/10654 7.556454187159181e-39 7.81352943270171e-38 3.8868793105951727e-38 5716/9491/5715/23198/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/10383/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/10376/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/10382/7314/5704/6233/5717/9861 52 Yaba_monkey_tumor_virus R-HSA-168898 Toll-like Receptor Cascades 59/511 155/10654 3.009697097505868e-38 3.0803328457126384e-37 1.532326986270442e-37 54106/1147/2353/64127/330/7311/1432/3725/8945/23118/329/7187/351/23291/841/10333/7099/8517/8772/81793/4615/9641/7098/7100/4790/6885/5599/5600/5606/7334/7316/7097/11213/3551/79155/10454/6416/8737/5608/5970/4792/7096/9261/3684/3654/4791/29110/7189/5594/5609/51284/7314/6233/5595/51311/10010/7867/257397/4214 59 Yaba_monkey_tumor_virus R-HSA-9006925 Intracellular signaling by second messengers 80/511 305/10654 4.44318908655541e-38 4.501533993752602e-37 2.2393106082161236e-37 5716/9491/5715/23198/930/1147/5718/7311/5711/5689/27161/941/3725/5701/5688/143471/5706/5687/5705/5684/1956/10197/8841/5720/5685/4615/29851/5683/331/5698/5708/808/5692/5686/5713/2534/5682/90865/7316/10213/5728/5709/5468/5694/5699/6009/1950/5695/842/5710/801/5700/122706/5707/3630/5702/8870/7157/5693/207/5721/5696/942/5719/3654/5691/5714/7189/5690/23112/5594/940/7314/5879/5704/6233/5595/805/5717/9861 80 Yaba_monkey_tumor_virus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 29/511 30/10654 7.394231466937923e-38 7.416414161338736e-37 3.6893323319248158e-37 7124/1147/330/7128/7311/7132/23118/329/81858/9099/27005/8517/10616/331/7186/56957/6885/8717/7316/1540/3551/7185/10454/8737/55072/7375/7314/6233/257397 29 Yaba_monkey_tumor_virus R-HSA-382556 ABC-family proteins mediated transport 49/511 103/10654 1.595434575580716e-37 1.584377108225206e-36 7.881563197761953e-37 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/10058/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Yaba_monkey_tumor_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 53/511 129/10654 1.9364411718756978e-36 1.9041671523444362e-35 9.472374772642731e-36 1147/2353/64127/330/7311/1432/3725/8945/23118/329/7187/351/23291/841/10333/7099/8517/8772/4615/9641/4790/6885/5599/5600/5606/7334/7316/7097/11213/3551/79155/10454/6416/8737/5608/5970/4792/7096/9261/3684/3654/4791/29110/7189/5594/5609/7314/6233/5595/10010/7867/257397/4214 53 Yaba_monkey_tumor_virus R-HSA-156902 Peptide chain elongation 45/511 89/10654 4.8870632595811805e-36 4.758955776077596e-35 2.367366361820623e-35 6158/7311/6204/6223/6224/6146/51065/6154/6138/6202/6228/23521/9349/4736/6188/6232/6206/6194/6191/6128/6135/6164/6155/1938/6235/6129/6218/1915/6181/6124/6207/6222/6137/6176/6170/6139/6136/6122/6133/6229/6231/6233/6125/6230/6130 45 Yaba_monkey_tumor_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 46/511 94/10654 5.537153630989441e-36 5.340158742194625e-35 2.6564886853127477e-35 1147/2353/64127/330/7311/1432/3725/8945/23118/329/7187/351/23291/841/8517/8772/9641/7098/4790/6885/5599/5600/5606/7334/7316/3551/79155/10454/6416/8737/5608/5970/4792/9261/3654/4791/29110/7189/5594/5609/7314/6233/5595/10010/7867/257397 46 Yaba_monkey_tumor_virus R-HSA-5688426 Deubiquitination 76/511 297/10654 2.3933969916818917e-35 2.2862639834827973e-34 1.1373134577014705e-34 5716/9491/5715/23198/5718/64127/330/7128/7311/5711/5689/5701/5688/143471/329/5706/5687/114548/5705/7187/5684/9099/27005/10197/10318/8517/60/5720/5685/7040/5683/5698/5708/7186/5692/56957/5686/5713/6885/2033/5682/90865/7316/10213/5728/5709/1540/5694/5699/5695/79155/5710/7417/5700/122706/10454/5707/5702/8737/7157/4792/5693/5721/5696/5719/5691/5714/7189/7375/5690/4609/7314/5704/6233/5717/9861 76 Yaba_monkey_tumor_virus R-HSA-5689880 Ub-specific processing proteases 66/511 220/10654 2.5571680094801646e-35 2.4196599184043443e-34 1.2036719329628581e-34 5716/9491/5715/23198/5718/330/7311/5711/5689/5701/5688/143471/329/5706/5687/5705/5684/9099/27005/10197/8517/5720/5685/5683/5698/5708/7186/5692/5686/5713/6885/5682/90865/7316/10213/5728/5709/1540/5694/5699/5695/5710/7417/5700/122706/10454/5707/5702/8737/7157/4792/5693/5721/5696/5719/5691/5714/7189/7375/5690/4609/7314/5704/6233/5717/9861 66 Yaba_monkey_tumor_virus R-HSA-156842 Eukaryotic Translation Elongation 45/511 93/10654 6.148176288536807e-35 5.763197025609735e-34 2.8669311960319197e-34 6158/7311/6204/6223/6224/6146/51065/6154/6138/6202/6228/23521/9349/4736/6188/6232/6206/6194/6191/6128/6135/6164/6155/1938/6235/6129/6218/1915/6181/6124/6207/6222/6137/6176/6170/6139/6136/6122/6133/6229/6231/6233/6125/6230/6130 45 Yaba_monkey_tumor_virus R-HSA-5683057 MAPK family signaling cascades 75/511 294/10654 8.836641687673736e-35 8.206621863645145e-34 4.082425107170907e-34 5716/9491/5715/3315/23198/5718/7311/5711/5689/27161/3725/5701/5688/143471/5706/3567/5687/5705/3558/5684/3562/1956/10197/60/5720/5685/5683/1437/5698/5708/1843/808/5692/5686/5713/2335/2534/5682/7316/10213/5709/5694/5699/1950/3559/5695/5710/801/5700/10642/122706/5707/5702/998/3569/5693/5721/5696/5719/5691/5714/5690/23112/5594/5605/4609/7314/5879/5704/6233/5595/805/5717/9861/3716 75 Yaba_monkey_tumor_virus R-HSA-166166 MyD88-independent TLR4 cascade 46/511 99/10654 1.107476272212801e-34 1.0098170009358541e-33 5.023385196448494e-34 1147/2353/64127/330/7311/1432/3725/8945/23118/329/7187/351/23291/841/7099/8517/8772/9641/4790/6885/5599/5600/5606/7334/7316/3551/79155/10454/6416/8737/5608/5970/4792/9261/3654/4791/29110/7189/5594/5609/7314/6233/5595/10010/7867/257397 46 Yaba_monkey_tumor_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 46/511 99/10654 1.107476272212801e-34 1.0098170009358541e-33 5.023385196448494e-34 1147/2353/64127/330/7311/1432/3725/8945/23118/329/7187/351/23291/841/7099/8517/8772/9641/4790/6885/5599/5600/5606/7334/7316/3551/79155/10454/6416/8737/5608/5970/4792/9261/3654/4791/29110/7189/5594/5609/7314/6233/5595/10010/7867/257397 46 Yaba_monkey_tumor_virus R-HSA-2262752 Cellular responses to stress 94/511 479/10654 1.2664227418226845e-33 1.1443441531965338e-32 5.692597246315338e-33 5716/9491/5715/23198/7295/2353/5718/7311/5711/3552/5689/1432/3725/5701/1051/6782/5688/1387/143471/5706/5687/5705/10383/5684/259217/10197/5720/2908/3576/5685/5683/3309/5698/5708/5692/5686/4790/5713/5599/2033/5600/5606/5682/23043/9448/10376/7316/10213/5709/5694/5699/6009/5695/4217/1915/3456/5710/5052/5700/122706/3301/5707/6416/8655/5702/5608/6774/3569/7157/5970/5693/6648/9261/5721/5696/5719/6667/5691/7422/5714/5690/23112/10382/5594/829/5609/9530/7314/5704/6233/5595/7867/5717/9861 94 Yaba_monkey_tumor_virus R-HSA-192823 Viral mRNA Translation 43/511 89/10654 2.1910484105606385e-33 1.962162103386e-32 9.760873558324647e-33 6158/7311/6204/6223/6224/6146/51065/6154/6138/6202/6228/23521/9349/4736/6188/6232/6206/6194/6191/6128/6135/6164/6155/6235/6129/6218/6181/6124/6207/6222/6137/6176/6170/6139/6136/6122/6133/6229/6231/6233/6125/6230/6130 43 Yaba_monkey_tumor_virus R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 44/511 95/10654 3.9221543701567025e-33 3.4813458701479405e-32 1.731812921708688e-32 6158/7311/6204/6223/6224/6146/51065/6154/6138/26986/6202/6228/23521/9349/4736/6188/6232/6206/6194/6191/6128/6135/6164/6155/6235/6129/6218/6181/6124/6207/6222/6137/6176/6170/6139/6136/6122/6133/6229/6231/6233/6125/6230/6130 44 Yaba_monkey_tumor_virus R-HSA-5358351 Signaling by Hedgehog 53/511 149/10654 1.1782654612012874e-32 1.0366668926183255e-31 5.156951326033336e-32 5716/9491/5715/23198/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/10383/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/10376/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/6868/5690/10382/7314/5704/6233/5717/9861 53 Yaba_monkey_tumor_virus R-HSA-69239 Synthesis of DNA 48/511 119/10654 1.2920475936594072e-32 1.1268902056003352e-31 5.605771710705345e-32 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-5663202 Diseases of signal transduction 82/511 377/10654 1.3194099775245125e-32 1.1408346616009361e-31 5.675139104778755e-32 5716/9491/5715/23198/4000/930/1147/5718/7311/5711/5689/941/5701/5688/1387/143471/5706/5687/5705/23164/5684/1956/10197/8841/60/5720/5685/29851/7040/5683/5698/5708/808/5692/5686/5713/2335/2534/2033/142678/5682/7316/10213/5728/5709/5694/5699/1950/5695/842/5710/801/5700/122706/5707/5702/6774/4851/5693/207/5721/5696/942/5719/5691/5714/6868/5690/6772/5594/5605/9530/940/4609/7314/5879/5704/6233/5595/805/5717/9861 82 Yaba_monkey_tumor_virus R-HSA-8953897 Cellular responses to external stimuli 94/511 493/10654 1.4352576886204554e-32 1.230396121099416e-31 6.1206670661817e-32 5716/9491/5715/23198/7295/2353/5718/7311/5711/3552/5689/1432/3725/5701/1051/6782/5688/1387/143471/5706/5687/5705/10383/5684/259217/10197/5720/2908/3576/5685/5683/3309/5698/5708/5692/5686/4790/5713/5599/2033/5600/5606/5682/23043/9448/10376/7316/10213/5709/5694/5699/6009/5695/4217/1915/3456/5710/5052/5700/122706/3301/5707/6416/8655/5702/5608/6774/3569/7157/5970/5693/6648/9261/5721/5696/5719/6667/5691/7422/5714/5690/23112/10382/5594/829/5609/9530/7314/5704/6233/5595/7867/5717/9861 94 Yaba_monkey_tumor_virus R-HSA-157118 Signaling by NOTCH 65/511 235/10654 1.9765355987489677e-32 1.6800552589366225e-31 8.357518945646839e-32 2324/5716/9491/5715/5718/7311/5711/5689/27161/3725/5701/5688/1387/5706/5687/5705/5684/1956/10197/8841/5720/5685/5683/5698/5708/5692/5686/5713/2033/142678/5682/7316/595/10213/5709/5584/5694/5699/1950/5695/5710/5700/3002/5707/5702/4851/7157/5693/207/5721/5696/5719/5691/5714/6868/5690/2683/23112/6772/4609/7314/5704/6233/5717/9861 65 Yaba_monkey_tumor_virus R-HSA-2408557 Selenocysteine synthesis 43/511 93/10654 2.3276126409103755e-32 1.945496232360922e-31 9.677968349048404e-32 6158/7311/6204/6223/6224/6146/51065/6154/6138/6202/6228/23521/9349/4736/6188/6232/6206/6194/6191/6128/6135/6164/6155/6235/6129/6218/6181/6124/6207/6222/6137/6176/6170/6139/6136/6122/6133/6229/6231/6233/6125/6230/6130 43 Yaba_monkey_tumor_virus R-HSA-72764 Eukaryotic Translation Termination 43/511 93/10654 2.3276126409103755e-32 1.945496232360922e-31 9.677968349048404e-32 6158/7311/6204/6223/6224/6146/51065/6154/6138/6202/6228/23521/9349/4736/6188/6232/6206/6194/6191/6128/6135/6164/6155/6235/6129/6218/6181/6124/6207/6222/6137/6176/6170/6139/6136/6122/6133/6229/6231/6233/6125/6230/6130 43 Yaba_monkey_tumor_virus R-HSA-5684996 MAPK1/MAPK3 signaling 67/511 255/10654 6.372445217283762e-32 5.28228310159968e-31 2.6276981583231866e-31 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/3567/5687/5705/3558/5684/3562/1956/10197/60/5720/5685/5683/1437/5698/5708/1843/808/5692/5686/5713/2335/2534/5682/7316/10213/5709/5694/5699/1950/3559/5695/5710/801/5700/122706/5707/5702/3569/5693/5721/5696/5719/5691/5714/5690/5594/5605/7314/5704/6233/5595/805/5717/9861/3716 67 Yaba_monkey_tumor_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 43/511 95/10654 7.174397650530442e-32 5.850342149172385e-31 2.9102819737710138e-31 1147/2353/64127/7311/1432/3725/8945/23118/351/23291/10333/7099/8517/4615/4790/6885/5599/5600/5606/7334/7316/7097/11213/3551/79155/10454/6416/5608/5970/4792/7096/9261/3654/4791/7189/5594/5609/7314/6233/5595/7867/257397/4214 43 Yaba_monkey_tumor_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 43/511 95/10654 7.174397650530442e-32 5.850342149172385e-31 2.9102819737710138e-31 1147/2353/64127/7311/1432/3725/8945/23118/351/23291/10333/7099/8517/4615/4790/6885/5599/5600/5606/7334/7316/7097/11213/3551/79155/10454/6416/5608/5970/4792/7096/9261/3654/4791/7189/5594/5609/7314/6233/5595/7867/257397/4214 43 Yaba_monkey_tumor_virus R-HSA-5673001 RAF/MAP kinase cascade 66/511 249/10654 1.0650018077560341e-31 8.614490428865339e-31 4.285321365673685e-31 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/3567/5687/5705/3558/5684/3562/1956/10197/60/5720/5685/5683/1437/5698/5708/1843/808/5692/5686/5713/2335/2534/5682/7316/10213/5709/5694/5699/1950/3559/5695/5710/801/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/5594/5605/7314/5704/6233/5595/805/5717/9861/3716 66 Yaba_monkey_tumor_virus R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs 49/511 130/10654 1.269743077551119e-31 1.0188418454270179e-30 5.068279736919835e-31 5716/9491/5715/23198/5718/7311/5711/6688/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 49 Yaba_monkey_tumor_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 42/511 92/10654 2.4270607315083505e-31 1.932017391827679e-30 9.61091718241402e-31 54106/1147/2353/64127/7311/1432/3725/8945/23118/351/23291/7099/8517/4615/4790/6885/5599/5600/5606/7334/7316/3551/79155/10454/6416/5608/5970/4792/9261/3654/4791/7189/5594/5609/51284/7314/6233/5595/51311/7867/257397/4214 42 Yaba_monkey_tumor_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 43/511 98/10654 3.642567535698843e-31 2.8542931549265154e-30 1.4198824111194504e-30 1147/2353/64127/7311/1432/3725/8945/23118/351/23291/10333/7099/8517/4615/4790/6885/5599/5600/5606/7334/7316/7097/11213/3551/79155/10454/6416/5608/5970/4792/7096/9261/3654/4791/7189/5594/5609/7314/6233/5595/7867/257397/4214 43 Yaba_monkey_tumor_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 43/511 98/10654 3.642567535698843e-31 2.8542931549265154e-30 1.4198824111194504e-30 1147/2353/64127/7311/1432/3725/8945/23118/351/23291/10333/7099/8517/4615/4790/6885/5599/5600/5606/7334/7316/7097/11213/3551/79155/10454/6416/5608/5970/4792/7096/9261/3654/4791/7189/5594/5609/7314/6233/5595/7867/257397/4214 43 Yaba_monkey_tumor_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 42/511 93/10654 4.234130881146041e-31 3.266794825991907e-30 1.6250834313062538e-30 54106/1147/2353/64127/7311/1432/3725/8945/23118/351/23291/7099/8517/4615/4790/6885/5599/5600/5606/7334/7316/3551/79155/10454/6416/5608/5970/4792/9261/3654/4791/7189/5594/5609/51284/7314/6233/5595/51311/7867/257397/4214 42 Yaba_monkey_tumor_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 42/511 93/10654 4.234130881146041e-31 3.266794825991907e-30 1.6250834313062538e-30 54106/1147/2353/64127/7311/1432/3725/8945/23118/351/23291/7099/8517/4615/4790/6885/5599/5600/5606/7334/7316/3551/79155/10454/6416/5608/5970/4792/9261/3654/4791/7189/5594/5609/51284/7314/6233/5595/51311/7867/257397/4214 42 Yaba_monkey_tumor_virus R-HSA-69306 DNA Replication 48/511 127/10654 4.670407918120097e-31 3.575892474713326e-30 1.778845603205244e-30 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-69275 G2/M Transition 58/511 196/10654 1.0151778734710962e-30 7.713813690087194e-30 3.837275215512756e-30 5716/9491/5715/23198/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/10133/10383/5684/23291/10197/5720/5685/5683/5698/5708/5692/5686/5713/2033/5682/10376/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/8655/5702/7157/5693/5721/5696/5719/5691/5714/5690/10382/5500/7314/5704/6233/5717/9861 58 Yaba_monkey_tumor_virus R-HSA-9607240 FLT3 Signaling 67/511 267/10654 1.3296601528900626e-30 1.0027437092847616e-29 4.9881987532242944e-30 5716/9491/5715/54106/23198/5718/7311/5711/5689/5701/5688/143471/5706/3567/5687/5705/3558/5684/3562/1956/10197/60/5720/5685/5683/1437/5698/5708/1843/808/5692/5686/5713/2335/2534/5682/7316/10213/5709/5694/5699/1950/3559/5695/5710/801/5700/122706/5707/5702/5693/5721/5696/5719/5691/5714/5690/5594/5605/7314/5704/6233/5595/805/5717/9861/3716 67 Yaba_monkey_tumor_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 40/511 85/10654 1.519234592034703e-30 1.1204355116255934e-29 5.573662512573136e-30 1147/2353/64127/7311/1432/3725/8945/23118/351/23291/8517/81793/4615/7100/4790/6885/5599/5600/5606/7334/7316/3551/79155/10454/6416/5608/5970/4792/9261/3654/4791/7189/5594/5609/7314/6233/5595/7867/257397/4214 40 Yaba_monkey_tumor_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 40/511 85/10654 1.519234592034703e-30 1.1204355116255934e-29 5.573662512573136e-30 1147/2353/64127/7311/1432/3725/8945/23118/351/23291/8517/81793/4615/7100/4790/6885/5599/5600/5606/7334/7316/3551/79155/10454/6416/5608/5970/4792/9261/3654/4791/7189/5594/5609/7314/6233/5595/7867/257397/4214 40 Yaba_monkey_tumor_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 40/511 85/10654 1.519234592034703e-30 1.1204355116255934e-29 5.573662512573136e-30 1147/2353/64127/7311/1432/3725/8945/23118/351/23291/8517/81793/4615/7100/4790/6885/5599/5600/5606/7334/7316/3551/79155/10454/6416/5608/5970/4792/9261/3654/4791/7189/5594/5609/7314/6233/5595/7867/257397/4214 40 Yaba_monkey_tumor_virus R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 45/511 112/10654 1.545343850539285e-30 1.1313721767086882e-29 5.628067500235275e-30 6158/6727/7311/6204/6223/6224/6146/51065/6154/6138/6202/6228/23521/9349/4736/6188/6232/6206/6194/6191/6128/6135/6164/6155/6235/6129/6218/29927/6181/6124/6207/6222/6137/6176/6170/6139/6136/6122/6133/6229/6231/6233/6125/6230/6130 45 Yaba_monkey_tumor_virus R-HSA-72689 Formation of a pool of free 40S subunits 43/511 101/10654 1.7228484205553854e-30 1.2521862071138054e-29 6.2290629393078e-30 6158/7311/6204/6223/6224/6146/51065/6154/6138/6202/6228/23521/9349/4736/6188/6232/6206/6194/6191/6128/6135/6164/6155/6235/6129/6218/6181/6124/6207/6222/6137/6176/6170/6139/6136/6122/6133/6229/6231/6233/6125/6230/6130 43 Yaba_monkey_tumor_virus R-HSA-453274 Mitotic G2-G2/M phases 58/511 198/10654 1.8655965440067867e-30 1.346182254416408e-29 6.696650979622998e-30 5716/9491/5715/23198/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/10133/10383/5684/23291/10197/5720/5685/5683/5698/5708/5692/5686/5713/2033/5682/10376/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/8655/5702/7157/5693/5721/5696/5719/5691/5714/5690/10382/5500/7314/5704/6233/5717/9861 58 Yaba_monkey_tumor_virus R-HSA-69206 G1/S Transition 48/511 131/10654 2.4976150310280232e-30 1.789362768657934e-29 8.901274621859271e-30 5716/9491/5715/5718/7311/5711/5689/5701/5688/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/595/10213/5709/5694/5699/5695/5710/5700/5707/5702/5693/207/5721/5696/5719/5691/5714/5690/4609/7314/5704/6233/5717/9861 48 Yaba_monkey_tumor_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 42/511 97/10654 3.6032445650566495e-30 2.56315907712895e-29 1.2750563074556565e-29 54106/1147/2353/64127/7311/1432/3725/8945/23118/351/23291/7099/8517/4615/4790/6885/5599/5600/5606/7334/7316/3551/79155/10454/6416/5608/5970/4792/9261/3654/4791/7189/5594/5609/51284/7314/6233/5595/51311/7867/257397/4214 42 Yaba_monkey_tumor_virus R-HSA-8878171 Transcriptional regulation by RUNX1 63/511 239/10654 4.0340824182089906e-30 2.8494258207490267e-29 1.4174611313795857e-29 5716/9491/5715/23198/5718/7311/5711/6688/5689/27161/5701/5688/1387/143471/5706/5687/5705/3558/5684/3562/10197/5720/5685/5683/1437/5698/5708/5692/5686/5713/2033/5682/7316/595/50943/10213/5709/5694/5699/3559/5695/5710/5700/3458/122706/5707/5702/7082/1493/5693/5721/5696/5719/5691/9021/5714/5690/23112/7314/5704/6233/5717/9861 63 Yaba_monkey_tumor_virus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 33/511 55/10654 5.250441851408564e-30 3.68265257130265e-29 1.8319539474182254e-29 7295/1147/64127/330/7128/7311/834/1432/23118/329/114548/351/841/8517/598/4790/6885/5600/7334/7316/1540/3551/842/10454/5608/5970/3654/4791/7189/835/7314/6233/257397 33 Yaba_monkey_tumor_virus R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 44/511 111/10654 1.4041963648173557e-29 9.780617735498665e-29 4.8654172289724165e-29 6158/7311/6204/6223/6224/6146/51065/6154/6138/26986/6202/6228/23521/9349/4736/6188/6232/6206/6194/6191/6128/6135/6164/6155/6235/6129/6218/6181/6124/6207/6222/6137/6176/6170/6139/6136/6122/6133/6229/6231/6233/6125/6230/6130 44 Yaba_monkey_tumor_virus R-HSA-927802 Nonsense-Mediated Decay (NMD) 44/511 115/10654 8.371947810578786e-29 5.751413461651043e-28 2.8610694031826564e-28 6158/7311/6204/6223/6224/6146/51065/6154/6138/26986/6202/6228/23521/9349/4736/6188/6232/6206/6194/6191/6128/6135/6164/6155/6235/6129/6218/6181/6124/6207/6222/6137/6176/6170/6139/6136/6122/6133/6229/6231/6233/6125/6230/6130 44 Yaba_monkey_tumor_virus R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 44/511 115/10654 8.371947810578786e-29 5.751413461651043e-28 2.8610694031826564e-28 6158/7311/6204/6223/6224/6146/51065/6154/6138/26986/6202/6228/23521/9349/4736/6188/6232/6206/6194/6191/6128/6135/6164/6155/6235/6129/6218/6181/6124/6207/6222/6137/6176/6170/6139/6136/6122/6133/6229/6231/6233/6125/6230/6130 44 Yaba_monkey_tumor_virus R-HSA-69242 S Phase 51/511 161/10654 1.1481306333432013e-28 7.833843709137626e-28 3.8969847490488896e-28 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/595/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/207/5721/5696/5719/5691/5714/5690/4609/7314/5704/6233/5717/9861 51 Yaba_monkey_tumor_virus R-HSA-69481 G2/M Checkpoints 52/511 168/10654 1.15683879289939e-28 7.839927765392489e-28 3.900011293273904e-28 5716/9491/5715/23198/5718/7311/5711/5689/9025/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7334/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/7157/5693/5721/10971/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 52 Yaba_monkey_tumor_virus R-HSA-453279 Mitotic G1-G1/S phases 49/511 149/10654 2.0164019576874135e-28 1.3573497742016617e-27 6.752204365551636e-28 5716/9491/5715/5718/7311/5711/5689/5701/5688/5706/5687/5705/4067/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/595/10213/5709/5694/5699/5695/5710/5700/5707/5702/5693/207/5721/5696/5719/5691/5714/5690/4609/7314/5704/6233/5717/9861 49 Yaba_monkey_tumor_virus R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 43/511 112/10654 3.0468396000442136e-28 2.037320079229564e-27 1.0134750669620754e-27 6158/7311/6204/6223/6224/6146/51065/6154/6138/6202/6228/23521/9349/4736/6188/6232/6206/6194/6191/6128/6135/6164/6155/6235/6129/6218/6181/6124/6207/6222/6137/6176/6170/6139/6136/6122/6133/6229/6231/6233/6125/6230/6130 43 Yaba_monkey_tumor_virus R-HSA-68882 Mitotic Anaphase 56/511 201/10654 3.530478895791024e-28 2.3450796903830445e-27 1.1665716253781425e-27 5716/9491/5715/23198/4000/5718/7311/5711/5689/5701/5688/143471/55920/5706/5687/5705/10383/5684/10197/5720/5685/6232/5683/5698/5708/8815/5692/5686/5713/5682/10376/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/8655/5702/5693/5721/5696/5719/5691/5714/5690/10382/7314/5704/6233/5717/9861 56 Yaba_monkey_tumor_virus R-HSA-72613 Eukaryotic Translation Initiation 44/511 119/10654 4.582938049384078e-28 3.0043704990406735e-27 1.4945391368476457e-27 6158/7311/6204/6223/6224/6146/51065/6154/6138/26986/6202/6228/23521/9349/4736/6188/6232/6206/6194/6191/6128/6135/6164/6155/6235/6129/6218/6181/6124/6207/6222/6137/6176/6170/6139/6136/6122/6133/6229/6231/6233/6125/6230/6130 44 Yaba_monkey_tumor_virus R-HSA-72737 Cap-dependent Translation Initiation 44/511 119/10654 4.582938049384078e-28 3.0043704990406735e-27 1.4945391368476457e-27 6158/7311/6204/6223/6224/6146/51065/6154/6138/26986/6202/6228/23521/9349/4736/6188/6232/6206/6194/6191/6128/6135/6164/6155/6235/6129/6218/6181/6124/6207/6222/6137/6176/6170/6139/6136/6122/6133/6229/6231/6233/6125/6230/6130 44 Yaba_monkey_tumor_virus R-HSA-2555396 Mitotic Metaphase and Anaphase 56/511 202/10654 4.676270366245135e-28 3.045648816457059e-27 1.5150732423788067e-27 5716/9491/5715/23198/4000/5718/7311/5711/5689/5701/5688/143471/55920/5706/5687/5705/10383/5684/10197/5720/5685/6232/5683/5698/5708/8815/5692/5686/5713/5682/10376/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/8655/5702/5693/5721/5696/5719/5691/5714/5690/10382/7314/5704/6233/5717/9861 56 Yaba_monkey_tumor_virus R-HSA-2467813 Separation of Sister Chromatids 54/511 190/10654 1.1414396215230966e-27 7.386218970243005e-27 3.6743115830352986e-27 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/55920/5706/5687/5705/10383/5684/10197/5720/5685/6232/5683/5698/5708/5692/5686/5713/5682/10376/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/8655/5702/5693/5721/5696/5719/5691/5714/5690/10382/7314/5704/6233/5717/9861 54 Yaba_monkey_tumor_virus R-HSA-162906 HIV Infection 59/511 233/10654 3.2008802513369813e-27 2.0580018539044824e-26 1.0237633192535285e-26 5716/9491/5715/23198/163/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/10197/7852/5720/5685/5683/5698/5708/8815/5692/5686/5713/2534/5682/7316/10213/5709/5694/5699/1175/5695/5710/5700/122706/5707/5702/292/5693/1234/5721/5696/5719/5691/5714/5690/940/7314/5879/5704/6233/5717/9861/4869 59 Yaba_monkey_tumor_virus R-HSA-2408522 Selenoamino acid metabolism 43/511 118/10654 3.82278235258876e-27 2.4421978978640296e-26 1.2148835636118487e-26 6158/7311/6204/6223/6224/6146/51065/6154/6138/6202/6228/23521/9349/4736/6188/6232/6206/6194/6191/6128/6135/6164/6155/6235/6129/6218/6181/6124/6207/6222/6137/6176/6170/6139/6136/6122/6133/6229/6231/6233/6125/6230/6130 43 Yaba_monkey_tumor_virus R-HSA-168638 NOD1/2 Signaling Pathway 26/511 36/10654 4.424934986426398e-27 2.8089935388516945e-26 1.3973478904504415e-26 1147/64127/330/7128/7311/834/1432/23118/329/841/8517/6885/5600/7334/7316/1540/3551/842/10454/5608/3654/7189/835/7314/6233/257397 26 Yaba_monkey_tumor_virus R-HSA-6783783 Interleukin-10 signaling 29/511 47/10654 5.252464724636216e-27 3.3133472445346693e-26 1.6482411648312254e-26 6364/3557/7124/5743/7132/3552/941/6347/3383/3576/1437/2920/6352/6351/6774/3569/1435/6348/1234/942/1440/3627/3586/7133/3606/3554/3553/2919/3716 29 Yaba_monkey_tumor_virus R-HSA-450294 MAP kinase activation 32/511 64/10654 1.047162028953149e-25 6.5643969690000525e-25 3.2654921166038987e-025 1147/2353/64127/7311/1432/3725/8945/23118/23291/8517/4790/6885/5599/5600/5606/7334/7316/3551/79155/10454/6416/5608/9261/3654/7189/5594/5609/7314/6233/5595/7867/257397 32 Yaba_monkey_tumor_virus R-HSA-5619115 Disorders of transmembrane transporters 50/511 176/10654 1.154531939108265e-25 7.192518850469502e-25 3.5779544892926944e-25 5716/9491/5715/23198/5718/7311/5711/5689/5701/5688/143471/5706/5687/5705/5684/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/213/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/10058/5719/5691/5714/5690/7314/5704/6233/5717/9861 50 Yaba_monkey_tumor_virus R-HSA-448424 Interleukin-17 signaling 33/511 72/10654 6.5227101626707e-25 4.038443390838711e-24 2.0089438707640754e-24 3605/1147/2353/64127/7311/1432/3725/8945/23118/23291/8517/4790/6885/5599/5600/5606/7334/7316/3551/79155/10454/6416/5608/9261/3654/7189/5594/5609/7314/6233/5595/7867/257397 33 Yaba_monkey_tumor_virus R-HSA-168273 Influenza Viral RNA Transcription and Replication 43/511 134/10654 1.4687901323240097e-24 9.038015354116452e-24 4.496005958809045e-24 6158/7311/6204/6223/6224/6146/51065/6154/6138/6202/6228/23521/9349/4736/6188/6232/6206/6194/6191/6128/6135/6164/6155/6235/6129/6218/6181/6124/6207/6222/6137/6176/6170/6139/6136/6122/6133/6229/6231/6233/6125/6230/6130 43 Yaba_monkey_tumor_virus R-HSA-168255 Influenza Life Cycle 44/511 144/10654 4.011824413966614e-24 2.453573101956411e-23 1.2205422158024228e-23 6158/7311/6204/6223/6224/6146/51065/6154/6138/6202/6228/23521/1213/9349/4736/6188/6232/6206/6194/6191/6128/6135/6164/6155/6235/6129/6218/6181/6124/6207/6222/6137/6176/6170/6139/6136/6122/6133/6229/6231/6233/6125/6230/6130 44 Yaba_monkey_tumor_virus R-HSA-195721 Signaling by WNT 66/511 331/10654 5.6528942471203614e-24 3.4362745029464984e-23 1.709391944583765e-23 5716/9491/5715/23198/163/5718/7311/5711/5689/27161/8945/5701/5688/1387/143471/5706/5687/1213/5705/5684/10197/857/5720/5685/5683/331/5698/5708/808/5692/5686/5713/6885/2033/5682/7316/10213/5709/5694/5699/1175/5695/5710/801/4772/5700/122706/5707/5702/5693/207/5721/5696/5719/5691/5714/5690/23112/4609/7314/5879/5704/6233/805/5717/9861 66 Yaba_monkey_tumor_virus R-HSA-201681 TCF dependent signaling in response to WNT 55/511 233/10654 8.469292600996271e-24 5.117289445059795e-23 2.5456212383463743e-23 5716/9491/5715/23198/5718/7311/5711/5689/8945/5701/5688/1387/143471/5706/5687/5705/5684/10197/857/5720/5685/5683/331/5698/5708/5692/5686/5713/2033/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/207/5721/5696/5719/5691/5714/5690/4609/7314/5704/6233/5717/9861 55 Yaba_monkey_tumor_virus R-HSA-168254 Influenza Infection 45/511 155/10654 1.2868957820701647e-23 7.729080655187875e-23 3.844869843688989e-23 6158/7311/6204/6223/6224/6146/51065/6154/6138/6202/6228/23521/1213/9349/4736/6188/6232/6206/6194/7040/6191/6128/6135/6164/6155/6235/6129/6218/6181/6124/6207/6222/6137/6176/6170/6139/6136/6122/6133/6229/6231/6233/6125/6230/6130 45 Yaba_monkey_tumor_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 37/511 108/10654 2.0950377173399526e-22 1.2507873991023646e-21 6.222104498866777e-22 3605/7124/2353/5743/3552/6347/4318/4312/3383/598/3576/7040/3687/4843/2335/6356/4313/595/3565/7412/6774/3569/7157/3162/207/5451/3684/3586/9021/7422/7133/3606/3553/6772/4609/3596/3716 37 Yaba_monkey_tumor_virus R-HSA-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 17/511 18/10654 5.011061752761538e-22 2.9740206733845103e-21 1.479441464222341e-21 8792/330/329/115650/4050/7187/10673/7186/51330/958/9020/8742/8600/4049/959/8740/4055 17 Yaba_monkey_tumor_virus R-HSA-983169 Class I MHC mediated antigen processing & presentation 67/511 371/10654 8.49299582233834e-22 5.010867535179621e-21 2.4926811268039465e-21 4012/5716/9491/5715/23198/1147/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/23291/10333/10197/7099/8517/5720/5685/4615/10616/5683/3309/5698/5708/5692/5686/5713/23376/142678/5682/7334/7316/10213/5709/5694/7097/5699/3551/5695/29927/5710/5700/122706/5707/5702/7096/5693/5721/5696/5719/5691/9021/5714/5690/7314/5704/6233/4360/5717/9861 67 Yaba_monkey_tumor_virus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 19/511 24/10654 2.127907355780872e-21 1.2481234373381372e-20 6.208852487781677e-21 64127/7311/1432/23118/8517/6885/5600/5606/7334/7316/10454/5608/9261/3654/7189/7314/6233/7867/257397 19 Yaba_monkey_tumor_virus R-HSA-8951664 Neddylation 51/511 234/10654 1.8160122684651155e-20 1.0589885495758784e-19 5.267991525412881e-20 5716/9491/5715/23198/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/23291/10197/5720/5685/5683/5698/5708/5692/5686/5713/5682/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/9021/5714/5690/7314/5704/6233/5717/9861 51 Yaba_monkey_tumor_virus R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 44/511 185/10654 2.377394002154735e-19 1.3783388347752597e-18 6.856615497543928e-19 6158/7311/6204/6223/6224/6146/51065/6154/6138/6202/6228/23521/9349/4736/6188/6232/6206/6194/6191/6128/6135/6164/6155/6235/6129/6218/6181/4691/6124/6207/6222/6137/6176/6170/6139/6136/6122/6133/6229/6231/6233/6125/6230/6130 44 Yaba_monkey_tumor_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 29/511 78/10654 6.018056014892478e-19 3.4690288407684797e-18 1.7256857538167178e-18 1147/7128/7311/1387/7187/351/841/8517/8772/9641/7186/4790/2033/8887/7316/1540/3551/3456/8737/5970/4792/4791/29110/7189/3439/7314/6233/10010/4214 29 Yaba_monkey_tumor_virus R-HSA-69620 Cell Cycle Checkpoints 55/511 293/10654 8.297802577385699e-19 4.7558262772102035e-18 2.36580957695087e-18 5716/9491/5715/23198/5718/7311/5711/5689/9025/5701/5688/143471/55920/5706/5687/5705/5684/10197/5720/5685/6232/5683/5698/5708/5692/5686/5713/5682/7334/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/8655/5702/7157/5693/5721/10971/5696/5719/5691/5714/5690/7314/5704/6233/5717/9861 55 Yaba_monkey_tumor_virus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 20/511 33/10654 9.263038683331725e-19 5.2788794314668866e-18 2.6260049855856685e-18 1147/64127/7311/23118/351/8517/4790/6885/7334/7316/3551/10454/5970/4792/3654/4791/7189/7314/6233/257397 20 Yaba_monkey_tumor_virus R-HSA-8868773 rRNA processing in the nucleus and cytosol 44/511 195/10654 2.1089913249155e-18 1.1950950841187834e-17 5.9450602914656374e-18 6158/7311/6204/6223/6224/6146/51065/6154/6138/6202/6228/23521/9349/4736/6188/6232/6206/6194/6191/6128/6135/6164/6155/6235/6129/6218/6181/4691/6124/6207/6222/6137/6176/6170/6139/6136/6122/6133/6229/6231/6233/6125/6230/6130 44 Yaba_monkey_tumor_virus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 56/511 309/10654 2.142421282958818e-18 1.207218284723424e-17 6.0053677594469525e-18 4012/5716/9491/5715/23198/5718/7311/5711/5689/8945/5701/5688/143471/5706/5687/5705/5684/23291/10197/5720/5685/10616/5683/5698/5708/5692/5686/5713/23376/142678/5682/7334/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/5702/5693/5721/5696/5719/5691/9021/5714/5690/7314/5704/6233/5717/9861 56 Yaba_monkey_tumor_virus R-HSA-5357786 TNFR1-induced proapoptotic signaling 13/511 13/10654 6.139722408877278e-18 3.440302556482631e-17 1.7113957199693206e-17 7124/7128/7132/9099/841/27005/8772/7186/56957/8717/1540/8737/7375 13 Yaba_monkey_tumor_virus R-HSA-5675482 Regulation of necroptotic cell death 15/511 18/10654 9.578086777655192e-18 5.3371227988823095e-17 2.6549784401219656e-17 355/330/7311/329/841/8772/331/7186/8717/8837/7316/8743/8737/7314/6233 15 Yaba_monkey_tumor_virus R-HSA-72312 rRNA processing 44/511 205/10654 1.6117528181295335e-17 8.931425837480232e-17 4.442982470447216e-17 6158/7311/6204/6223/6224/6146/51065/6154/6138/6202/6228/23521/9349/4736/6188/6232/6206/6194/6191/6128/6135/6164/6155/6235/6129/6218/6181/4691/6124/6207/6222/6137/6176/6170/6139/6136/6122/6133/6229/6231/6233/6125/6230/6130 44 Yaba_monkey_tumor_virus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 16/511 23/10654 1.1213089155754985e-16 6.179521111660576e-16 3.0740336956783474e-16 64127/7311/23118/8517/6885/5599/7334/7316/10454/6416/3654/7189/5609/7314/6233/257397 16 Yaba_monkey_tumor_virus R-HSA-5213460 RIPK1-mediated regulated necrosis 15/511 20/10654 1.6642824402051647e-16 9.072148301770544e-16 4.512985564400733e-16 355/330/7311/329/841/8772/331/7186/8717/8837/7316/8743/8737/7314/6233 15 Yaba_monkey_tumor_virus R-HSA-5218859 Regulated Necrosis 15/511 20/10654 1.6642824402051647e-16 9.072148301770544e-16 4.512985564400733e-16 355/330/7311/329/841/8772/331/7186/8717/8837/7316/8743/8737/7314/6233 15 Yaba_monkey_tumor_virus R-HSA-5260271 Diseases of Immune System 16/511 24/10654 3.216681520516999e-16 1.7345868629454572e-15 8.628789138228961e-16 1147/7187/10333/7099/8517/81793/4615/7098/7100/4790/7097/3551/5970/4792/7096/4791 16 Yaba_monkey_tumor_virus R-HSA-5602358 Diseases associated with the TLR signaling cascade 16/511 24/10654 3.216681520516999e-16 1.7345868629454572e-15 8.628789138228961e-16 1147/7187/10333/7099/8517/81793/4615/7098/7100/4790/7097/3551/5970/4792/7096/4791 16 Yaba_monkey_tumor_virus R-HSA-68886 M Phase 59/511 395/10654 2.9337272753533854e-15 1.5735446295077246e-14 7.827676490388429e-15 5716/9491/5715/140609/23198/4000/5718/7311/5711/5689/5701/5688/143471/55920/5706/5687/5705/10383/5684/10197/5720/5685/6232/5683/5698/5708/8815/5692/5686/5713/5682/10376/7316/10213/5709/5694/5699/5695/5710/5700/122706/5707/8655/5702/5693/5721/5696/5719/5691/5714/5690/10382/5594/7314/5704/6233/5595/5717/9861 59 Yaba_monkey_tumor_virus R-HSA-193639 p75NTR signals via NF-kB 13/511 16/10654 3.0092520295680113e-15 1.6054679710939975e-14 7.986480750365271e-15 7311/4615/4790/7316/5584/3551/5970/4792/3654/7189/8878/7314/6233 13 Yaba_monkey_tumor_virus R-HSA-72766 Translation 49/511 291/10654 6.89475223031847e-15 3.6589611042377916e-14 1.8201685085886685e-14 6158/6727/7311/6204/6223/6224/6146/51065/6154/6138/26986/6202/6228/23521/9349/4736/6188/6232/6206/6194/6191/6128/6135/6164/6155/1938/6235/6129/6218/29927/1915/6181/6124/6207/6222/6137/6176/6170/7284/6139/6136/6122/6133/6229/6231/6233/6125/6230/6130 49 Yaba_monkey_tumor_virus R-HSA-380108 Chemokine receptors bind chemokines 21/511 59/10654 1.2578581561629726e-13 6.640167003323481e-13 3.303184299286698e-13 6364/10563/9034/2833/6347/7852/3576/6356/2920/3579/1236/6352/6351/6376/6348/1234/6354/3627/4283/2919/6387 21 Yaba_monkey_tumor_virus R-HSA-209560 NF-kB is activated and signals survival 11/511 13/10654 1.9908112336627643e-13 1.04303412572637e-12 5.188625445708132e-13 7311/4790/7316/3551/5970/4792/3654/7189/8878/7314/6233 11 Yaba_monkey_tumor_virus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 12/511 16/10654 1.9966356145509776e-13 1.04303412572637e-12 5.188625445708132e-13 1147/7311/8945/23291/8517/4790/7316/3551/79155/6416/7314/6233 12 Yaba_monkey_tumor_virus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 13/511 20/10654 3.487822950732462e-13 1.812583637090497e-12 9.0167879937125e-13 1147/330/7311/329/8517/7098/7334/7316/3551/8737/7189/7314/6233 13 Yaba_monkey_tumor_virus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 10/511 11/10654 6.234945326025884e-13 3.2235310113422487e-12 1.6035616302421428e-12 7311/23118/7098/6885/7316/10454/7189/7314/6233/257397 10 Yaba_monkey_tumor_virus R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 19/511 51/10654 7.214230359932634e-13 3.7107041287243245e-12 1.845908335011103e-12 6204/6223/6224/51065/6202/6228/6188/6232/6206/6194/6191/6235/6218/6207/6222/6229/6231/6233/6230 19 Yaba_monkey_tumor_virus R-HSA-72649 Translation initiation complex formation 20/511 58/10654 9.705187020360025e-13 4.966480908888319e-12 2.470600777470812e-12 6204/6223/6224/51065/26986/6202/6228/6188/6232/6206/6194/6191/6235/6218/6207/6222/6229/6231/6233/6230 20 Yaba_monkey_tumor_virus R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 20/511 59/10654 1.4037150540461105e-12 7.146833498519029e-12 3.555228082382348e-12 6204/6223/6224/51065/26986/6202/6228/6188/6232/6206/6194/6191/6235/6218/6207/6222/6229/6231/6233/6230 20 Yaba_monkey_tumor_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 11/511 15/10654 3.190480626353269e-12 1.616187913248651e-11 8.03980763897634e-12 54106/7311/4615/7334/7316/3654/7189/51284/7314/6233/51311 11 Yaba_monkey_tumor_virus R-HSA-72702 Ribosomal scanning and start codon recognition 19/511 58/10654 1.0300088917278081e-11 5.1914518512713145e-11 2.58251369838128e-11 6204/6223/6224/51065/6202/6228/6188/6232/6206/6194/6191/6235/6218/6207/6222/6229/6231/6233/6230 19 Yaba_monkey_tumor_virus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 9/511 10/10654 1.2023737086870273e-11 6.029904149065442e-11 2.9996059890402685e-11 7311/23118/6885/7316/10454/7189/7314/6233/257397 9 Yaba_monkey_tumor_virus R-HSA-209543 p75NTR recruits signalling complexes 10/511 13/10654 1.4853793794882995e-11 7.412117003118231e-11 3.6871946890675775e-11 7311/4615/7316/5584/3551/3654/7189/8878/7314/6233 10 Yaba_monkey_tumor_virus R-HSA-937041 IKK complex recruitment mediated by RIP1 13/511 25/10654 1.8742397226937636e-11 9.306249712187352e-11 4.629440482318103e-11 1147/330/7311/329/7099/8517/7334/7316/3551/8737/7189/7314/6233 13 Yaba_monkey_tumor_virus R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 9/511 11/10654 6.332482858107519e-11 3.128808032848198e-10 1.5564412106523018e-10 7311/23118/6885/7316/10454/7189/7314/6233/257397 9 Yaba_monkey_tumor_virus R-HSA-5689896 Ovarian tumor domain proteases 15/511 38/10654 7.437359532348612e-11 3.656701770071401e-10 1.8190445915032207e-10 64127/7128/7311/7187/10318/8517/56957/7316/5728/79155/8737/7157/7189/7314/6233 15 Yaba_monkey_tumor_virus R-HSA-937039 IRAK1 recruits IKK complex 10/511 15/10654 1.4291596177923502e-10 6.958481051678288e-10 3.4615312152967505e-10 1147/7311/8517/7334/7316/3551/3654/7189/7314/6233 10 Yaba_monkey_tumor_virus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 10/511 15/10654 1.4291596177923502e-10 6.958481051678288e-10 3.4615312152967505e-10 1147/7311/8517/7334/7316/3551/3654/7189/7314/6233 10 Yaba_monkey_tumor_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 9/511 12/10654 2.4255650064315005e-10 1.1752858461114952e-9 5.846518245860824e-10 7311/7187/9641/7098/7316/29110/7314/6233/10010 9 Yaba_monkey_tumor_virus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 10/511 16/10654 3.6482543446274604e-10 1.7592303402217996e-9 8.751379348954535e-10 7311/23118/7099/6885/7316/10454/7189/7314/6233/257397 10 Yaba_monkey_tumor_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 18/511 63/10654 4.6500481914964485e-10 2.2315781512301136e-9 1.110109716831688e-9 1147/7311/1387/8517/4615/7098/4790/2033/7316/51428/3551/8737/5970/4792/4791/29110/7314/6233 18 Yaba_monkey_tumor_virus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 11/511 21/10654 6.333207529018226e-10 3.0248605483834666e-9 1.504732014413353e-9 1147/8517/4615/7098/4790/3551/8737/5970/4792/4791/29110 11 Yaba_monkey_tumor_virus R-HSA-2559583 Cellular Senescence 32/511 195/10654 7.834645523199611e-10 3.7242414501275872e-9 1.852642543275937e-9 7295/2353/7311/3552/1432/3725/1051/3576/4790/5599/5600/5606/23043/9448/7316/4217/3456/6416/5608/6774/3569/7157/5970/9261/6667/23112/5594/5609/7314/6233/5595/7867 32 Yaba_monkey_tumor_virus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 10/511 17/10654 8.48159320981208e-10 3.993914549033575e-9 1.9867927756120214e-9 1147/8517/4615/7098/4790/3551/8737/5970/4792/4791 10 Yaba_monkey_tumor_virus R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 10/511 17/10654 8.48159320981208e-10 3.993914549033575e-9 1.9867927756120214e-9 7311/23118/7099/6885/7316/10454/7189/7314/6233/257397 10 Yaba_monkey_tumor_virus R-HSA-3371378 Regulation by c-FLIP 8/511 11/10654 3.855695973226538e-9 1.7903995653454712e-8 8.906432218856625e-9 355/841/8772/7186/8717/8837/8743/8737 8 Yaba_monkey_tumor_virus R-HSA-5218900 CASP8 activity is inhibited 8/511 11/10654 3.855695973226538e-9 1.7903995653454712e-8 8.906432218856625e-9 355/841/8772/7186/8717/8837/8743/8737 8 Yaba_monkey_tumor_virus R-HSA-69416 Dimerization of procaspase-8 8/511 11/10654 3.855695973226538e-9 1.7903995653454712e-8 8.906432218856625e-9 355/841/8772/7186/8717/8837/8743/8737 8 Yaba_monkey_tumor_virus R-HSA-933542 TRAF6 mediated NF-kB activation 11/511 24/10654 3.928893514773224e-9 1.8159816568283612e-8 9.033691612915392e-9 1147/351/8517/7186/4790/3551/5970/4792/4791/7189/4214 11 Yaba_monkey_tumor_virus R-HSA-2559580 Oxidative Stress Induced Senescence 24/511 125/10654 4.45646591743322e-9 2.0503831721034492e-8 1.0199733678722097e-8 7295/2353/7311/1432/3725/5599/5600/5606/23043/9448/7316/4217/3456/6416/5608/7157/9261/23112/5594/5609/7314/6233/5595/7867 24 Yaba_monkey_tumor_virus R-HSA-109606 Intrinsic Pathway for Apoptosis 15/511 53/10654 1.5402947932769316e-8 7.054409487017179e-8 3.509251295425453e-8 841/598/836/331/5599/842/637/3002/8655/6774/7157/207/10971/5594/5595 15 Yaba_monkey_tumor_virus R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 11/511 27/10654 1.7990973334094024e-8 8.202248297316504e-8 4.080249454717975e-8 355/841/7099/8772/836/7186/8717/8837/842/8743/8737 11 Yaba_monkey_tumor_virus R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 9/511 17/10654 2.1586264065445802e-8 9.796842922010018e-8 4.8734885291837624e-8 355/841/7099/8772/7186/8717/8837/8743/8737 9 Yaba_monkey_tumor_virus R-HSA-193704 p75 NTR receptor-mediated signalling 20/511 97/10654 2.4842522754055593e-8 1.1223896541584575e-7 5.583383492376648e-8 7311/6610/8841/836/4615/4790/5599/7316/5584/3551/5970/4792/3654/7189/6868/835/8878/7314/5879/6233 20 Yaba_monkey_tumor_virus R-HSA-5210891 Uptake and function of anthrax toxins 8/511 13/10654 2.760531464213988e-8 1.2416202056531976e-7 6.176501836381544e-8 808/5606/801/6416/5608/5605/5609/805 8 Yaba_monkey_tumor_virus R-HSA-194138 Signaling by VEGF 21/511 107/10654 2.778897130015568e-8 1.2443008131275065e-7 6.189836652384301e-8 2324/3315/1003/1432/5590/3791/60/857/808/8829/2534/5600/4846/801/998/9261/207/7422/5879/805/7867 21 Yaba_monkey_tumor_virus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 9/511 18/10654 4.134565972071931e-8 1.8430976311058428e-7 9.168581383682317e-8 7311/7187/7099/9641/7316/29110/7314/6233/10010 9 Yaba_monkey_tumor_virus R-HSA-450341 Activation of the AP-1 family of transcription factors 7/511 10/10654 5.9345801899207636e-8 2.633798199332091e-7 1.3101960922321574e-7 2353/1432/3725/5599/5600/5594/5595 7 Yaba_monkey_tumor_virus R-HSA-6798695 Neutrophil degranulation 51/511 480/10654 6.107034330108857e-8 2.698394463920345e-7 1.3423298272532336e-7 6727/5718/7130/4353/5689/1432/5701/3920/4318/197/10383/5806/5788/5683/3687/968/5708/5686/4790/5713/960/1938/10213/5709/7097/5657/3579/5695/1915/5707/5315/8655/5702/3848/5175/9961/3684/5719/7133/383/2683/56729/728/5594/1654/6402/22931/5879/5717/9861/2919 51 Yaba_monkey_tumor_virus R-HSA-5627123 RHO GTPases activate PAKs 10/511 24/10654 6.303674951313523e-8 2.7730640246348527e-7 1.379474573833153e-7 10627/4637/808/79784/801/998/4627/5500/5879/805 10 Yaba_monkey_tumor_virus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 50/511 473/10654 9.765228747450401e-8 4.2770849055426865e-7 2.1276572862751044e-7 2324/54106/5802/3315/163/1003/7311/3178/1432/627/23118/4318/3479/1213/4670/5590/4067/3791/1956/60/857/348/808/8829/2335/2534/5600/4846/7316/1175/1950/801/3630/3185/998/6774/9261/207/7422/6868/6772/5594/5605/7314/5879/6233/5595/805/7867/6387 50 Yaba_monkey_tumor_virus R-HSA-4420097 VEGFA-VEGFR2 Pathway 19/511 99/10654 1.8549150238779492e-7 8.089042473693839e-7 4.023934651341638e-7 3315/1003/1432/5590/3791/60/857/808/2534/5600/4846/801/998/9261/207/7422/5879/805/7867 19 Yaba_monkey_tumor_virus R-HSA-5669034 TNFs bind their physiological receptors 10/511 29/10654 5.179080315046672e-7 2.248752188741044e-6 1.1186530277202653e-6 7132/7293/8764/8744/10673/3604/8600/7133/4049/8740 10 Yaba_monkey_tumor_virus R-HSA-9009391 Extra-nuclear estrogen signaling 16/511 77/10654 5.610484162740792e-7 2.4255670755297473e-6 1.2066104778308237e-6 3315/2353/4318/5590/1956/857/808/4313/4846/595/1950/801/207/5594/5595/805 16 Yaba_monkey_tumor_virus R-HSA-451927 Interleukin-2 family signaling 12/511 44/10654 6.732535358066467e-7 2.898168654137625e-6 1.4417084977291644e-6 3567/3558/3562/1437/3600/3559/3578/84868/6774/6772/59067/3716 12 Yaba_monkey_tumor_virus R-HSA-400253 Circadian Clock 15/511 70/10654 8.351107543138322e-7 3.579555925541768e-6 1.7806680051496017e-6 7311/8945/1387/6720/8841/2908/5465/2033/10135/7316/6256/5500/7314/6233/5054 15 Yaba_monkey_tumor_virus R-HSA-199418 Negative regulation of the PI3K/AKT network 19/511 110/10654 1.0214733606449716e-6 4.359735237135772e-6 2.1687721072596487e-6 930/941/1956/4615/29851/2534/90865/5728/1950/3630/8870/207/942/3654/7189/5594/940/5879/5595 19 Yaba_monkey_tumor_virus R-HSA-8848021 Signaling by PTK6 13/511 54/10654 1.1073612331650626e-6 4.6864274973188095e-6 2.3312868066632897e-6 7311/1956/6421/2908/7316/595/1950/6774/207/9021/7314/5879/6233 13 Yaba_monkey_tumor_virus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 13/511 54/10654 1.1073612331650626e-6 4.6864274973188095e-6 2.3312868066632897e-6 7311/1956/6421/2908/7316/595/1950/6774/207/9021/7314/5879/6233 13 Yaba_monkey_tumor_virus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 15/511 72/10654 1.2238185274392073e-6 5.157520937065231e-6 2.5656345953391603e-6 4012/6517/4644/10383/60/808/10376/801/4627/207/10971/10382/4641/5879/805 15 Yaba_monkey_tumor_virus R-HSA-2871796 FCERI mediated MAPK activation 10/511 32/10654 1.4641924460956413e-6 6.144707211020619e-6 3.0567153466167538e-6 2353/3725/4067/5599/6416/5594/5609/5879/5595/4214 10 Yaba_monkey_tumor_virus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 18/511 103/10654 1.6481507363553813e-6 6.887896619018531e-6 3.4264186361072405e-6 930/941/1956/4615/29851/2534/90865/1950/3630/8870/207/942/3654/7189/5594/940/5879/5595 18 Yaba_monkey_tumor_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 12/511 48/10654 1.865577380807763e-6 7.764207937552641e-6 3.8623440860575655e-6 7311/3567/3558/4067/3562/1437/2534/7316/3559/7314/6233/3716 12 Yaba_monkey_tumor_virus R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 16/511 84/10654 1.9197970407672133e-6 7.95684475987403e-6 3.958172237162501e-6 6517/7124/1051/1387/6720/8841/7040/3952/4790/5465/2033/5468/1050/5970/6256/9370 16 Yaba_monkey_tumor_virus R-HSA-622312 Inflammasomes 8/511 20/10654 2.0033512622126287e-6 8.26897660905048e-6 4.113443787259199e-6 7295/834/114548/351/598/4790/5970/4791 8 Yaba_monkey_tumor_virus R-HSA-2691230 Signaling by NOTCH1 HD Domain Mutants in Cancer 7/511 15/10654 2.577432211699624e-6 1.0508798814368792e-5 5.22765455004545e-6 7311/142678/7316/4851/6868/7314/6233 7 Yaba_monkey_tumor_virus R-HSA-2691232 Constitutive Signaling by NOTCH1 HD Domain Mutants 7/511 15/10654 2.577432211699624e-6 1.0508798814368792e-5 5.22765455004545e-6 7311/142678/7316/4851/6868/7314/6233 7 Yaba_monkey_tumor_virus R-HSA-844456 The NLRP3 inflammasome 7/511 15/10654 2.577432211699624e-6 1.0508798814368792e-5 5.22765455004545e-6 7295/834/114548/351/4790/5970/4791 7 Yaba_monkey_tumor_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 10/511 34/10654 2.728610046191584e-6 1.1080145248300237e-5 5.5118736922855776e-6 7128/7311/7187/9641/8887/7316/1540/29110/7314/6233 10 Yaba_monkey_tumor_virus R-HSA-114608 Platelet degranulation 20/511 129/10654 3.0799398925118622e-6 1.2456369807215313e-5 6.196483484934731e-6 1191/3920/5099/6403/3479/197/351/7040/3309/808/2335/213/1950/801/308/5175/7123/7422/805/5054 20 Yaba_monkey_tumor_virus R-HSA-205043 NRIF signals cell death from the nucleus 7/511 16/10654 4.3932547577004234e-6 1.769652418463263e-5 8.803224498626087e-6 7311/5599/7316/7189/8878/7314/6233 7 Yaba_monkey_tumor_virus R-HSA-933541 TRAF6 mediated IRF7 activation 9/511 29/10654 5.299327333785219e-6 2.1260901263146297e-5 1.0576341710375551e-5 1387/9641/7186/2033/3456/29110/7189/3439/10010 9 Yaba_monkey_tumor_virus R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 20/511 134/10654 5.600360455529912e-6 2.237912962906973e-5 1.113261000596007e-5 1191/3920/5099/6403/3479/197/351/7040/3309/808/2335/213/1950/801/308/5175/7123/7422/805/5054 20 Yaba_monkey_tumor_virus R-HSA-389359 CD28 dependent Vav1 pathway 6/511 12/10654 8.53140706636033e-6 3.3822139476519414e-5 1.68249925086532e-5 941/2534/998/942/940/5879 6 Yaba_monkey_tumor_virus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 6/511 12/10654 8.53140706636033e-6 3.3822139476519414e-5 1.68249925086532e-5 1147/841/8517/8772/3551/8737 6 Yaba_monkey_tumor_virus R-HSA-5339562 Uptake and actions of bacterial toxins 9/511 31/10654 9.788202879404725e-6 3.865184050410606e-5 1.9227551449804556e-5 808/5606/1938/801/6416/5608/5605/5609/805 9 Yaba_monkey_tumor_virus R-HSA-5626467 RHO GTPases activate IQGAPs 9/511 32/10654 1.3045424353308367e-5 5.131200245634624e-5 2.5525412356937733e-5 10383/60/808/10376/801/998/10382/5879/805 9 Yaba_monkey_tumor_virus R-HSA-445355 Smooth Muscle Contraction 10/511 40/10654 1.3598790078388071e-5 5.3279634564934516e-5 2.6504220794226753e-5 10627/7168/4637/7169/7171/808/801/7170/140465/805 10 Yaba_monkey_tumor_virus R-HSA-203615 eNOS activation 6/511 13/10654 1.5203124600839991e-5 5.933359523207203e-5 2.9515793818546613e-5 857/808/4846/801/207/805 6 Yaba_monkey_tumor_virus R-HSA-9012852 Signaling by NOTCH3 11/511 49/10654 1.536819941440312e-5 5.9745364390102054e-5 2.972063044645891e-5 7311/1387/1956/2033/142678/7316/1950/4851/6772/7314/6233 11 Yaba_monkey_tumor_virus R-HSA-2559585 Oncogene Induced Senescence 9/511 33/10654 1.7183136186096086e-5 6.628725228713221e-5 3.297492531258925e-5 7311/7316/7157/6667/23112/5594/7314/6233/5595 9 Yaba_monkey_tumor_virus R-HSA-389356 CD28 co-stimulation 9/511 33/10654 1.7183136186096086e-5 6.628725228713221e-5 3.297492531258925e-5 941/4067/2534/9020/998/207/942/940/5879 9 Yaba_monkey_tumor_virus R-HSA-76002 Platelet activation, signaling and aggregation 29/511 262/10654 2.2178359542095776e-5 8.522948130544852e-5 4.239783191350432e-5 1191/1432/3920/5099/6403/3479/5590/197/4067/351/7040/3309/808/2335/2534/213/1950/801/998/308/5175/207/7123/7422/5594/5879/5595/805/5054 29 Yaba_monkey_tumor_virus R-HSA-388841 Costimulation by the CD28 family 13/511 70/10654 2.34478460459407e-5 8.97640823819791e-5 4.4653591907496555e-5 941/29126/8764/4067/29851/2534/9020/998/1493/207/942/940/5879 13 Yaba_monkey_tumor_virus R-HSA-8939211 ESR-mediated signaling 26/511 223/10654 2.394292234638665e-5 9.131084073545935e-5 4.542303458950279e-5 3315/2353/27161/3725/1387/4318/5590/1956/857/808/2033/4313/4846/595/1950/801/1655/207/5451/6667/23112/5594/4609/5595/805/6387 26 Yaba_monkey_tumor_virus R-HSA-918233 TRAF3-dependent IRF activation pathway 6/511 14/10654 2.5530148330791485e-5 9.699522263554492e-5 4.825075880699826e-5 1387/7187/9641/2033/3456/29110 6 Yaba_monkey_tumor_virus R-HSA-375276 Peptide ligand-binding receptors 24/511 201/10654 3.321018807287856e-5 1.256974288192347e-4 6.252881488200372e-5 6364/10563/9034/2833/6347/351/7852/3576/6356/2920/3579/1236/6352/6351/6376/6348/1234/6354/3627/728/1906/4283/2919/6387 24 Yaba_monkey_tumor_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 7/511 21/10654 3.6195775306072254e-5 1.3648256628567848e-4 6.789393547715968e-5 5971/1387/4067/4790/2534/2033/5970 7 Yaba_monkey_tumor_virus R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 6/511 15/10654 4.0831959076853e-5 1.5338747173814068e-4 7.630336527667384e-5 7311/7316/51428/29110/7314/6233 6 Yaba_monkey_tumor_virus R-HSA-5218920 VEGFR2 mediated vascular permeability 8/511 29/10654 4.65395780554435e-5 1.7417610742391726e-4 8.664477611264814e-5 1003/857/808/4846/801/207/5879/805 8 Yaba_monkey_tumor_virus R-HSA-5602498 MyD88 deficiency (TLR2/4) 5/511 10/10654 5.1320591341888444e-5 1.906464930219041e-4 9.483805183647221e-5 10333/7099/4615/7097/7096 5 Yaba_monkey_tumor_virus R-HSA-8877330 RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) 5/511 10/10654 5.1320591341888444e-5 1.906464930219041e-4 9.483805183647221e-5 3558/50943/3559/3458/1493 5 Yaba_monkey_tumor_virus R-HSA-1295596 Spry regulation of FGF signaling 6/511 16/10654 6.269518166834426e-5 2.3118848240201946e-4 1.1500586730183891e-4 7311/7316/5594/7314/6233/5595 6 Yaba_monkey_tumor_virus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 6/511 16/10654 6.269518166834426e-5 2.3118848240201946e-4 1.1500586730183891e-4 7311/5590/7040/7316/7314/6233 6 Yaba_monkey_tumor_virus R-HSA-447115 Interleukin-12 family signaling 11/511 57/10654 6.871368639056493e-5 2.524535804019656e-4 1.255842966999336e-4 3458/3181/3185/998/6774/6648/5721/3586/6772/829/3716 11 Yaba_monkey_tumor_virus R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases 8/511 31/10654 7.857838919605983e-5 2.876427896483504e-4 1.4308934490561795e-4 2353/1432/3725/5599/5600/9261/5594/5595 8 Yaba_monkey_tumor_virus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 11/511 58/10654 8.119064193828965e-5 2.9187890273872587e-4 1.4519662055743933e-4 7311/1387/8841/2033/142678/7316/4851/6868/4609/7314/6233 11 Yaba_monkey_tumor_virus R-HSA-2644603 Signaling by NOTCH1 in Cancer 11/511 58/10654 8.119064193828965e-5 2.9187890273872587e-4 1.4519662055743933e-4 7311/1387/8841/2033/142678/7316/4851/6868/4609/7314/6233 11 Yaba_monkey_tumor_virus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 11/511 58/10654 8.119064193828965e-5 2.9187890273872587e-4 1.4519662055743933e-4 7311/1387/8841/2033/142678/7316/4851/6868/4609/7314/6233 11 Yaba_monkey_tumor_virus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 11/511 58/10654 8.119064193828965e-5 2.9187890273872587e-4 1.4519662055743933e-4 7311/1387/8841/2033/142678/7316/4851/6868/4609/7314/6233 11 Yaba_monkey_tumor_virus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 11/511 58/10654 8.119064193828965e-5 2.9187890273872587e-4 1.4519662055743933e-4 7311/1387/8841/2033/142678/7316/4851/6868/4609/7314/6233 11 Yaba_monkey_tumor_virus R-HSA-166520 Signaling by NTRKs 15/511 101/10654 8.728139523905106e-5 3.1265442651702937e-4 1.5553150880943684e-4 5802/163/1432/627/1213/2534/5600/1175/6774/9261/5594/5605/5879/5595/7867 15 Yaba_monkey_tumor_virus R-HSA-1059683 Interleukin-6 signaling 5/511 11/10654 9.038300884724467e-5 3.2033271333493425e-4 1.5935111100462703e-4 6774/3569/9021/6772/3716 5 Yaba_monkey_tumor_virus R-HSA-4755510 SUMOylation of immune response proteins 5/511 11/10654 9.038300884724467e-5 3.2033271333493425e-4 1.5935111100462703e-4 8517/9641/5970/4792/4791 5 Yaba_monkey_tumor_virus R-HSA-5603041 IRAK4 deficiency (TLR2/4) 5/511 11/10654 9.038300884724467e-5 3.2033271333493425e-4 1.5935111100462703e-4 10333/7099/4615/7097/7096 5 Yaba_monkey_tumor_virus R-HSA-202131 Metabolism of nitric oxide: eNOS activation and regulation 6/511 17/10654 9.298659454767359e-5 3.283998391947768e-4 1.6336414312675049e-4 857/808/4846/801/207/805 6 Yaba_monkey_tumor_virus R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 7/511 24/10654 9.501370015731923e-5 3.332123820202489e-4 1.657581666344104e-4 2353/1956/595/1950/207/5594/5595 7 Yaba_monkey_tumor_virus R-HSA-982772 Growth hormone receptor signaling 7/511 24/10654 9.501370015731923e-5 3.332123820202489e-4 1.657581666344104e-4 4067/6774/9021/6868/6772/5594/5595 7 Yaba_monkey_tumor_virus R-HSA-9006931 Signaling by Nuclear Receptors 30/511 299/10654 1.0183479433259108e-4 3.5588954256302735e-4 1.77039033609566e-4 3315/2353/27161/3725/1387/4318/5590/1956/6720/8841/857/348/808/2033/4313/4846/595/1950/801/1655/207/6256/5451/6667/23112/5594/4609/5595/805/6387 30 Yaba_monkey_tumor_virus R-HSA-2682334 EPH-Ephrin signaling 14/511 92/10654 1.141607051311949e-4 3.9758051127287665e-4 1.9777841459132448e-4 10627/163/4637/4318/1213/4067/60/79784/2534/4313/1175/998/4627/5879 14 Yaba_monkey_tumor_virus R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus 7/511 25/10654 1.265576859543177e-4 4.392296159591026e-4 2.184969701050686e-4 7311/1956/142678/7316/1950/7314/6233 7 Yaba_monkey_tumor_virus R-HSA-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation 5/511 12/10654 1.4884843869073343e-4 5.130411821539713e-4 2.55214903018295e-4 808/4846/801/207/805 5 Yaba_monkey_tumor_virus R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 5/511 12/10654 1.4884843869073343e-4 5.130411821539713e-4 2.55214903018295e-4 55367/834/8738/7157/835 5 Yaba_monkey_tumor_virus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 6/511 19/10654 0.00018777174063586561 6.40595428087664e-4 3.186674008643047e-4 7311/1956/7316/1950/7314/6233 6 Yaba_monkey_tumor_virus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 6/511 19/10654 0.00018777174063586561 6.40595428087664e-4 3.186674008643047e-4 7311/1956/7316/1950/7314/6233 6 Yaba_monkey_tumor_virus R-HSA-6804760 Regulation of TP53 Activity through Methylation 6/511 19/10654 0.00018777174063586561 6.40595428087664e-4 3.186674008643047e-4 7311/2033/7316/7157/7314/6233 6 Yaba_monkey_tumor_virus R-HSA-5628897 TP53 Regulates Metabolic Genes 13/511 86/10654 2.1313627371231242e-4 7.246633306218622e-4 3.6048739960619475e-4 7295/27161/4513/4697/5728/6009/5052/2539/2744/7157/207/10971/23112 13 Yaba_monkey_tumor_virus R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 15/511 110/10654 2.3190444443344237e-4 7.821271485802282e-4 3.8907306336467243e-4 2353/7311/3552/3725/1051/3576/4790/7316/6774/3569/5970/5594/7314/6233/5595 15 Yaba_monkey_tumor_virus R-HSA-111461 Cytochrome c-mediated apoptotic response 5/511 13/10654 2.3237675999691725e-4 7.821271485802282e-4 3.8907306336467243e-4 836/331/842/5594/5595 5 Yaba_monkey_tumor_virus R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 5/511 13/10654 2.3237675999691725e-4 7.821271485802282e-4 3.8907306336467243e-4 7311/7316/207/7314/6233 5 Yaba_monkey_tumor_virus R-HSA-9614085 FOXO-mediated transcription 11/511 65/10654 2.3557498848560156e-4 7.90239844317921e-4 3.9310876445053735e-4 7295/1387/6720/857/2908/2033/3630/6648/207/10971/56729 11 Yaba_monkey_tumor_virus R-HSA-6804757 Regulation of TP53 Degradation 8/511 36/10654 2.4390968127463894e-4 8.154713677282095e-4 4.0566031201466266e-4 7311/117584/9099/7316/7157/207/7314/6233 8 Yaba_monkey_tumor_virus R-HSA-5625900 RHO GTPases activate CIT 6/511 20/10654 2.574606846312409e-4 8.579171650668925e-4 4.2677518627455216e-4 10627/4637/79784/4627/5500/5879 6 Yaba_monkey_tumor_virus R-HSA-6806003 Regulation of TP53 Expression and Degradation 8/511 37/10654 2.983167034543081e-4 9.907670647836791e-4 4.928620335912932e-4 7311/117584/9099/7316/7157/207/7314/6233 8 Yaba_monkey_tumor_virus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 9/511 47/10654 3.3340759257715334e-4 0.0010999305848807123 5.471659728535002e-4 7311/1387/8841/2033/7316/4851/4609/7314/6233 9 Yaba_monkey_tumor_virus R-HSA-9020591 Interleukin-12 signaling 9/511 47/10654 3.3340759257715334e-4 0.0010999305848807123 5.471659728535002e-4 3458/3181/3185/998/6648/5721/3586/829/3716 9 Yaba_monkey_tumor_virus R-HSA-3700989 Transcriptional Regulation by TP53 33/511 365/10654 3.3447540218207105e-4 0.0010999305848807123 5.471659728535002e-4 355/7295/2353/7311/55367/834/27161/1432/3725/1387/117584/9099/4513/2033/5600/4697/7316/5728/6009/8738/5052/637/2539/2744/5608/7157/207/10971/23112/835/7314/6233/4869 33 Yaba_monkey_tumor_virus R-HSA-389513 CTLA4 inhibitory signaling 6/511 21/10654 3.459666483613086e-4 0.0011250372061826486 5.59655387238889e-4 941/4067/2534/1493/207/942 6 Yaba_monkey_tumor_virus R-HSA-445144 Signal transduction by L1 6/511 21/10654 3.459666483613086e-4 0.0011250372061826486 5.59655387238889e-4 1956/8829/5594/5605/5879/5595 6 Yaba_monkey_tumor_virus R-HSA-5218921 VEGFR2 mediated cell proliferation 6/511 21/10654 3.459666483613086e-4 0.0011250372061826486 5.59655387238889e-4 5590/3791/808/801/7422/805 6 Yaba_monkey_tumor_virus R-HSA-8863795 Downregulation of ERBB2 signaling 7/511 29/10654 3.477183787802802e-4 0.0011250372061826486 5.59655387238889e-4 7311/1956/7316/1950/207/7314/6233 7 Yaba_monkey_tumor_virus R-HSA-8982491 Glycogen metabolism 7/511 29/10654 3.477183787802802e-4 0.0011250372061826486 5.59655387238889e-4 7311/808/7316/801/7314/6233/805 7 Yaba_monkey_tumor_virus R-HSA-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 8/511 38/10654 3.622396164744055e-4 0.0011645074850122716 5.792900749287052e-4 7020/1387/1956/348/2033/7422/4609/4869 8 Yaba_monkey_tumor_virus R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 8/511 38/10654 3.622396164744055e-4 0.0011645074850122716 5.792900749287052e-4 3458/3181/3185/998/6648/5721/3586/829 8 Yaba_monkey_tumor_virus R-HSA-1236394 Signaling by ERBB4 10/511 58/10654 3.850040944570044e-4 0.0012337351653047136 6.137277308647052e-4 7311/23118/1956/348/7316/1950/6868/7314/6233/6387 10 Yaba_monkey_tumor_virus R-HSA-389357 CD28 dependent PI3K/Akt signaling 6/511 22/10654 4.5661366950903553e-4 0.0014401997186086874 7.164345559327469e-4 941/2534/9020/207/942/940 6 Yaba_monkey_tumor_virus R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 6/511 22/10654 4.5661366950903553e-4 0.0014401997186086874 7.164345559327469e-4 4000/3725/826/351/5052/6648 6 Yaba_monkey_tumor_virus R-HSA-8863678 Neurodegenerative Diseases 6/511 22/10654 4.5661366950903553e-4 0.0014401997186086874 7.164345559327469e-4 4000/3725/826/351/5052/6648 6 Yaba_monkey_tumor_virus R-HSA-912631 Regulation of signaling by CBL 6/511 22/10654 4.5661366950903553e-4 0.0014401997186086874 7.164345559327469e-4 7311/4067/2534/7316/7314/6233 6 Yaba_monkey_tumor_virus R-HSA-9613829 Chaperone Mediated Autophagy 6/511 22/10654 4.5661366950903553e-4 0.0014401997186086874 7.164345559327469e-4 7311/3920/7316/1915/7314/6233 6 Yaba_monkey_tumor_virus R-HSA-5675221 Negative regulation of MAPK pathway 8/511 40/10654 5.235461807020738e-4 0.00164613422960558 8.188777088031118e-4 7311/1843/7316/5594/5605/7314/6233/5595 8 Yaba_monkey_tumor_virus R-HSA-182971 EGFR downregulation 7/511 31/10654 5.389994775059461e-4 0.0016841634764438128 8.377955479187358e-4 7311/1956/7316/1950/998/7314/6233 7 Yaba_monkey_tumor_virus R-HSA-2122948 Activated NOTCH1 Transmits Signal to the Nucleus 7/511 31/10654 5.389994775059461e-4 0.0016841634764438128 8.377955479187358e-4 7311/142678/7316/4851/6868/7314/6233 7 Yaba_monkey_tumor_virus R-HSA-112409 RAF-independent MAPK1/3 activation 6/511 23/10654 5.930026640515194e-4 0.0018471480498250745 9.188730394260221e-4 1843/3569/5594/5605/5595/3716 6 Yaba_monkey_tumor_virus R-HSA-1474244 Extracellular matrix organization 28/511 301/10654 5.957603638800791e-4 0.001849992708890772 9.202881293112515e-4 4326/5802/8174/4318/4312/3383/826/351/3791/4322/836/1605/7040/3687/633/2335/4321/960/4313/7412/8754/5175/5339/3684/6868/3676/1634/5054 28 Yaba_monkey_tumor_virus R-HSA-3928665 EPH-ephrin mediated repulsion of cells 9/511 51/10654 6.27711132207074e-4 0.001943192177789183 9.666506714299971e-4 163/4318/1213/4067/60/2534/4313/1175/5879 9 Yaba_monkey_tumor_virus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 7/511 32/10654 6.618009721807263e-4 0.0020385214700773084 0.0010140727048503378 7311/7316/6667/4609/7314/6233/5054 7 Yaba_monkey_tumor_virus R-HSA-1980143 Signaling by NOTCH1 11/511 73/10654 6.625702883800625e-4 0.0020385214700773084 0.0010140727048503378 7311/1387/8841/2033/142678/7316/4851/6868/4609/7314/6233 11 Yaba_monkey_tumor_virus R-HSA-8986944 Transcriptional Regulation by MECP2 10/511 62/10654 6.681004836472617e-4 0.002049250107333956 0.0010194097191334366 27161/627/8841/808/5728/5468/801/3654/23112/805 10 Yaba_monkey_tumor_virus R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 6/511 24/10654 7.589989853495891e-4 0.00231390876080741 0.0011510654904997768 1432/5590/5600/5594/5879/5595 6 Yaba_monkey_tumor_virus R-HSA-6783589 Interleukin-6 family signaling 6/511 24/10654 7.589989853495891e-4 0.00231390876080741 0.0011510654904997768 6774/3569/3589/9021/6772/3716 6 Yaba_monkey_tumor_virus R-HSA-1980145 Signaling by NOTCH2 7/511 33/10654 8.057698638128274e-4 0.0024490520406189875 0.0012182931912193946 7311/2033/142678/7316/3002/7314/6233 7 Yaba_monkey_tumor_virus R-HSA-2562578 TRIF-mediated programmed cell death 4/511 10/10654 8.714002203892487e-4 0.002632573557380772 0.0013095868879660871 841/7099/8772/8737 4 Yaba_monkey_tumor_virus R-HSA-9020958 Interleukin-21 signaling 4/511 10/10654 8.714002203892487e-4 0.002632573557380772 0.0013095868879660871 6774/6772/59067/3716 4 Yaba_monkey_tumor_virus R-HSA-1643713 Signaling by EGFR in Cancer 6/511 25/10654 9.587172904217784e-4 0.0028876679948740052 0.0014364848922393644 7311/1956/7316/1950/7314/6233 6 Yaba_monkey_tumor_virus R-HSA-187687 Signalling to ERKs 7/511 34/10654 9.733818907517207e-4 0.002923059989293341 0.0014540908169439508 1432/5600/9261/5594/5605/5595/7867 7 Yaba_monkey_tumor_virus R-HSA-5633008 TP53 Regulates Transcription of Cell Death Genes 8/511 44/10654 0.0010194761583042587 0.003052342050087079 0.0015184028249370578 355/55367/834/1387/8738/637/7157/835 8 Yaba_monkey_tumor_virus R-HSA-2219528 PI3K/AKT Signaling in Cancer 13/511 101/10654 0.0010380257291694366 0.0030986303760623356 0.0015414291842929602 930/1147/941/1956/29851/2534/5728/1950/842/207/942/940/5879 13 Yaba_monkey_tumor_virus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 6/511 26/10654 0.0011965040201883223 0.0035611084042993686 0.0017714911934070428 7311/7040/7316/5500/7314/6233 6 Yaba_monkey_tumor_virus R-HSA-6802952 Signaling by BRAF and RAF fusions 10/511 67/10654 0.0012437430126652732 0.00369075219438837 0.0018359831454479586 4000/23164/60/808/2335/801/5594/5605/5595/805 10 Yaba_monkey_tumor_virus R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 9/511 56/10654 0.0012637830944521161 0.003726776767721567 0.0018539037496982974 1387/8841/6742/808/5465/801/6648/6256/805 9 Yaba_monkey_tumor_virus R-HSA-111471 Apoptotic factor-mediated response 5/511 18/10654 0.001267029788427771 0.003726776767721567 0.0018539037496982974 836/331/842/5594/5595 5 Yaba_monkey_tumor_virus R-HSA-1368082 RORA activates gene expression 5/511 18/10654 0.001267029788427771 0.003726776767721567 0.0018539037496982974 1387/6720/5465/2033/6256 5 Yaba_monkey_tumor_virus R-HSA-111458 Formation of apoptosome 4/511 11/10654 0.001317695769841821 0.003819794384830481 0.0019001758287344789 331/842/5594/5595 4 Yaba_monkey_tumor_virus R-HSA-193692 Regulated proteolysis of p75NTR 4/511 11/10654 0.001317695769841821 0.003819794384830481 0.0019001758287344789 4790/5970/7189/6868 4 Yaba_monkey_tumor_virus R-HSA-2025928 Calcineurin activates NFAT 4/511 11/10654 0.001317695769841821 0.003819794384830481 0.0019001758287344789 808/801/4772/805 4 Yaba_monkey_tumor_virus R-HSA-376172 DSCAM interactions 4/511 11/10654 0.001317695769841821 0.003819794384830481 0.0019001758287344789 1432/5599/5600/5879 4 Yaba_monkey_tumor_virus R-HSA-9627069 Regulation of the apoptosome activity 4/511 11/10654 0.001317695769841821 0.003819794384830481 0.0019001758287344789 331/842/5594/5595 4 Yaba_monkey_tumor_virus R-HSA-187037 Signaling by NTRK1 (TRKA) 11/511 80/10654 0.0014424471152389947 0.004169378837419918 0.0020740783637897267 163/1432/1213/5600/1175/6774/9261/5594/5605/5595/7867 11 Yaba_monkey_tumor_virus R-HSA-912526 Interleukin receptor SHC signaling 6/511 27/10654 0.0014769178045364647 0.004256748729741592 0.0021175409538726083 3567/3558/3562/1437/3559/3716 6 Yaba_monkey_tumor_virus R-HSA-437239 Recycling pathway of L1 8/511 47/10654 0.0015945694627863792 0.004530745527407191 0.0022538420317899026 163/1213/10383/60/10376/1175/10382/5594 8 Yaba_monkey_tumor_virus R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 8/511 47/10654 0.0015945694627863792 0.004530745527407191 0.0022538420317899026 60/808/2335/801/5594/5605/5595/805 8 Yaba_monkey_tumor_virus R-HSA-6802949 Signaling by RAS mutants 8/511 47/10654 0.0015945694627863792 0.004530745527407191 0.0022538420317899026 60/808/2335/801/5594/5605/5595/805 8 Yaba_monkey_tumor_virus R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 8/511 47/10654 0.0015945694627863792 0.004530745527407191 0.0022538420317899026 60/808/2335/801/5594/5605/5595/805 8 Yaba_monkey_tumor_virus R-HSA-9649948 Signaling downstream of RAS mutants 8/511 47/10654 0.0015945694627863792 0.004530745527407191 0.0022538420317899026 60/808/2335/801/5594/5605/5595/805 8 Yaba_monkey_tumor_virus R-HSA-5689901 Metalloprotease DUBs 7/511 37/10654 0.001644883305705056 0.004660502699497659 0.0023183903862747444 7311/114548/2033/7316/10213/7314/6233 7 Yaba_monkey_tumor_virus R-HSA-8876725 Protein methylation 5/511 19/10654 0.0016524790912105947 0.004668835291504863 0.0023225354758601093 808/1938/1915/801/805 5 Yellow_fever_virus R-HSA-909733 Interferon alpha/beta signaling 32/82 69/10654 8.601046656144411e-52 3.681247968829808e-49 2.1185735974082026e-49 3449/3440/3455/3448/10379/9021/3443/3660/3665/3434/3456/3444/3446/3452/6773/6772/3454/7297/8651/3663/5781/5777/3659/3662/4599/3445/3664/3451/3661/3441/5770/3716 32 Yellow_fever_virus R-HSA-912694 Regulation of IFNA signaling 22/82 26/10654 2.1194961749639303e-44 4.535721814422811e-42 2.6103268681134726e-42 3449/3440/3455/3448/9021/3443/3456/3444/3446/3452/6773/6772/3454/7297/8651/5781/5777/3445/3451/3441/5770/3716 22 Yellow_fever_virus R-HSA-913531 Interferon Signaling 37/82 199/10654 4.816029556345324e-43 6.870868833719328e-41 3.954213740999319e-41 3449/3717/3440/3455/3448/10379/9021/3459/3443/3660/3665/3434/3456/3444/3446/3452/6773/6772/3458/3460/3454/7297/8651/3663/5781/5777/3659/3662/4599/3445/3664/3451/3661/3441/5770/3716/23586 37 Yellow_fever_virus R-HSA-933541 TRAF6 mediated IRF7 activation 19/82 29/10654 1.3841602218073581e-34 1.4810514373338732e-32 8.523512944813732e-33 3449/64135/3440/3448/3443/3665/29110/3456/3444/3446/3452/57506/1387/3445/2033/3451/3661/3441/23586 19 Yellow_fever_virus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 22/82 78/10654 1.5151066182896553e-29 1.296931265255945e-27 7.463893656416408e-28 3449/64135/3440/3448/3443/3665/29110/3456/3444/3446/3452/57506/4790/1387/3445/2033/5970/3146/3451/3661/3441/23586 22 Yellow_fever_virus R-HSA-449147 Signaling by Interleukins 33/82 461/10654 4.076429726316208e-24 2.9078532047722284e-22 1.673481677119286e-22 3717/3605/7124/3559/3627/3586/2353/9021/3576/29110/282618/3563/4615/53832/163702/6773/6772/6352/3458/7297/8651/3588/5781/3725/5777/4790/3662/3569/5970/6597/3146/3716/1386 33 Yellow_fever_virus R-HSA-877300 Interferon gamma signaling 19/82 92/10654 1.1065418937994126e-22 6.7657132935164086e-21 3.893696287955828e-21 3717/10379/9021/3459/3660/3665/6772/3458/3460/8651/3663/5781/5777/3659/3662/3664/3661/5770/3716 19 Yellow_fever_virus R-HSA-877312 Regulation of IFNG signaling 11/82 14/10654 1.0001740762921134e-21 5.3509313081628067e-20 3.0794833401625603e-20 3717/9021/3459/6772/3458/3460/8651/5781/5777/5770/3716 11 Yellow_fever_virus R-HSA-918233 TRAF3-dependent IRF activation pathway 9/82 14/10654 1.1710657985141937e-16 5.569068464045277e-15 3.2050221854072674e-15 64135/3665/29110/3456/57506/1387/2033/3661/23586 9 Yellow_fever_virus R-HSA-8854691 Interleukin-20 family signaling 10/82 25/10654 1.232901595063074e-15 5.2768188268699564e-14 3.0368312973132567e-14 3717/282618/53832/163702/6773/6772/7297/3588/5781/3716 10 Yellow_fever_virus R-HSA-168898 Toll-like Receptor Cascades 16/82 155/10654 3.367486646447701e-14 1.3102584406178326e-12 7.540592107835045e-13 54106/7099/2353/3665/29110/4615/7098/8651/5781/3725/51284/4790/5970/3146/3661/1386 16 Yellow_fever_virus R-HSA-1059683 Interleukin-6 signaling 7/82 11/10654 3.966941736320256e-13 1.4148758859542246e-11 8.142669879815264e-12 3717/9021/6772/7297/5781/3569/3716 7 Yellow_fever_virus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 13/82 108/10654 1.422736727375339e-12 4.6840870716665e-11 2.695711693974327e-11 3717/3605/7124/3586/2353/9021/3576/6772/7297/8651/3662/3569/3716 13 Yellow_fever_virus R-HSA-983231 Factors involved in megakaryocyte development and platelet production 15/82 168/10654 1.971555037183689e-12 6.027325399390136e-11 3.4687509676765665e-11 3449/3717/3440/60/3448/3443/3660/3456/3444/3446/3452/3659/3445/3451/3441 15 Yellow_fever_virus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 13/82 129/10654 1.4317784760385722e-11 4.08534125163006e-10 2.3511309711791294e-10 7099/2353/3665/29110/4615/8651/5781/3725/4790/5970/3146/3661/1386 13 Yellow_fever_virus R-HSA-6783783 Interleukin-10 signaling 9/82 47/10654 6.4972933590459e-11 1.7380259735447782e-9 1.000241214484698e-9 7124/3627/3586/3576/6352/7297/3588/3569/3716 9 Yellow_fever_virus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 11/82 93/10654 1.0308911478262882e-10 2.451230062609174e-9 1.410693149657026e-9 54106/7099/2353/3665/4615/3725/51284/4790/5970/3146/1386 11 Yellow_fever_virus R-HSA-975155 MyD88 dependent cascade initiated on endosome 11/82 93/10654 1.0308911478262882e-10 2.451230062609174e-9 1.410693149657026e-9 54106/7099/2353/3665/4615/3725/51284/4790/5970/3146/1386 11 Yellow_fever_virus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 11/82 97/10654 1.6411163723298118e-10 3.6968305650376817e-9 2.1275414466768754e-9 54106/7099/2353/3665/4615/3725/51284/4790/5970/3146/1386 11 Yellow_fever_virus R-HSA-166166 MyD88-independent TLR4 cascade 11/82 99/10654 2.054241650847389e-10 4.186740126488964e-9 2.409486447610472e-9 7099/2353/3665/29110/5781/3725/4790/5970/3146/3661/1386 11 Yellow_fever_virus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 11/82 99/10654 2.054241650847389e-10 4.186740126488964e-9 2.409486447610472e-9 7099/2353/3665/29110/5781/3725/4790/5970/3146/3661/1386 11 Yellow_fever_virus R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 8/82 38/10654 3.5245127266933854e-10 6.85677930465804e-9 3.9461051581160396e-9 6599/6601/8289/2033/6598/6605/6597/6602 8 Yellow_fever_virus R-HSA-6783589 Interleukin-6 family signaling 7/82 24/10654 3.8392560883289574e-10 7.14435480784693e-9 4.111606062558244e-9 3717/9021/6772/7297/5781/3569/3716 7 Yellow_fever_virus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 9/82 63/10654 1.0219824504919392e-9 1.822535370043958e-8 1.048876725504885e-8 3665/29110/4615/7098/4790/1387/2033/5970/3661 9 Yellow_fever_virus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 10/82 92/10654 1.7978306578646564e-9 3.077886086264292e-8 1.771336311327704e-8 54106/7099/2353/4615/3725/51284/4790/5970/3146/1386 10 Yellow_fever_virus R-HSA-3247509 Chromatin modifying enzymes 15/82 274/10654 2.067281370816518e-9 3.2770238026276654e-8 1.8859408996922622e-8 3717/6599/6601/60/8850/8289/4790/1387/2033/5970/6598/6605/6597/6602/1386 15 Yellow_fever_virus R-HSA-4839726 Chromatin organization 15/82 274/10654 2.067281370816518e-9 3.2770238026276654e-8 1.8859408996922622e-8 3717/6599/6601/60/8850/8289/4790/1387/2033/5970/6598/6605/6597/6602/1386 15 Yellow_fever_virus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 10/82 94/10654 2.2265379651988964e-9 3.4034223182325986e-8 1.9586837738967736e-8 2353/3665/29110/7098/3725/4790/5970/3146/3661/1386 10 Yellow_fever_virus R-HSA-8878171 Transcriptional regulation by RUNX1 14/82 239/10654 3.1706344869210524e-9 4.6794191738007254e-8 2.69302529923603e-8 6599/6601/3559/9021/8850/8289/3458/5781/1387/2033/6598/6605/6597/6602 14 Yellow_fever_virus R-HSA-110056 MAPK3 (ERK1) activation 5/82 10/10654 5.837592281384336e-9 8.328298321441653e-8 4.792970504715561e-8 3717/7297/5781/3569/3716 5 Yellow_fever_virus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 6/82 21/10654 8.544468143804538e-9 1.1796878598543039e-7 6.789152956367614e-8 29110/4615/7098/4790/5970/3661 6 Yellow_fever_virus R-HSA-933542 TRAF6 mediated NF-kB activation 6/82 24/10654 2.0807320759307858e-8 2.6986464499950795e-7 1.5530823150488163e-7 64135/57506/4790/5970/3146/23586 6 Yellow_fever_virus R-HSA-982772 Growth hormone receptor signaling 6/82 24/10654 2.0807320759307858e-8 2.6986464499950795e-7 1.5530823150488163e-7 3717/9021/6772/8651/5777/5770 6 Yellow_fever_virus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 9/82 95/10654 4.1606697782638686e-8 5.087904757419817e-7 2.928110460492467e-7 7099/2353/4615/8651/3725/4790/5970/3146/1386 9 Yellow_fever_virus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 9/82 95/10654 4.1606697782638686e-8 5.087904757419817e-7 2.928110460492467e-7 7099/2353/4615/8651/3725/4790/5970/3146/1386 9 Yellow_fever_virus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 9/82 98/10654 5.4696626590215856e-8 6.327069238003349e-7 3.64125480003144e-7 7099/2353/4615/8651/3725/4790/5970/3146/1386 9 Yellow_fever_virus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 9/82 98/10654 5.4696626590215856e-8 6.327069238003349e-7 3.64125480003144e-7 7099/2353/4615/8651/3725/4790/5970/3146/1386 9 Yellow_fever_virus R-HSA-3214858 RMTs methylate histone arginines 8/82 79/10654 1.4582484950046085e-7 1.6424483048999274e-6 9.452358665680842e-7 3717/6599/6601/8289/6598/6605/6597/6602 8 Yellow_fever_virus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 5/82 18/10654 1.891172149890615e-7 2.0754402055209826e-6 1.1944245157203884e-6 7099/3665/29110/5781/3661 5 Yellow_fever_virus R-HSA-112409 RAF-independent MAPK1/3 activation 5/82 23/10654 7.2064015328565e-7 7.710849640156454e-6 4.437626207074793e-6 3717/7297/5781/3569/3716 5 Yellow_fever_virus R-HSA-449836 Other interleukin signaling 5/82 24/10654 9.04806688161001e-7 9.00598284960252e-6 5.182980784080153e-6 282618/163702/7297/3588/3716 5 Yellow_fever_virus R-HSA-5260271 Diseases of Immune System 5/82 24/10654 9.04806688161001e-7 9.00598284960252e-6 5.182980784080153e-6 7099/4615/7098/4790/5970 5 Yellow_fever_virus R-HSA-5602358 Diseases associated with the TLR signaling cascade 5/82 24/10654 9.04806688161001e-7 9.00598284960252e-6 5.182980784080153e-6 7099/4615/7098/4790/5970 5 Yellow_fever_virus R-HSA-451927 Interleukin-2 family signaling 6/82 44/10654 9.653836883445194e-7 9.390550422987598e-6 5.404301030445397e-6 3717/3559/3563/6772/5777/3716 6 Yellow_fever_virus R-HSA-9020956 Interleukin-27 signaling 4/82 11/10654 1.0324479948863786e-6 9.819727595808222e-6 5.651294287799125e-6 3717/6772/7297/3716 4 Yellow_fever_virus R-HSA-8984722 Interleukin-35 Signalling 4/82 12/10654 1.5396087935840674e-6 1.4020267311786827e-5 8.068722456857152e-6 3717/6772/7297/3716 4 Yellow_fever_virus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 4/82 12/10654 1.5396087935840674e-6 1.4020267311786827e-5 8.068722456857152e-6 3665/29110/7098/3661 4 Yellow_fever_virus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 6/82 48/10654 1.637616750458817e-6 1.4602082691591117e-5 8.403559640512352e-6 3717/3559/3563/5781/5777/3716 6 Yellow_fever_virus R-HSA-912526 Interleukin receptor SHC signaling 5/82 27/10654 1.6877247213094755e-6 1.4741758790213378e-5 8.483943819257085e-6 3717/3559/3563/5777/3716 5 Yellow_fever_virus R-HSA-9018519 Estrogen-dependent gene expression 9/82 150/10654 2.0880657215514354e-6 1.787384257648029e-5 1.0286471133537598e-5 2962/2353/8850/3725/2957/1387/5430/2033/1386 9 Yellow_fever_virus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 7/82 85/10654 3.756232125966592e-6 3.0333346224786822e-5 1.7456967576488234e-5 2353/4615/3725/4790/5970/3146/1386 7 Yellow_fever_virus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 7/82 85/10654 3.756232125966592e-6 3.0333346224786822e-5 1.7456967576488234e-5 2353/4615/3725/4790/5970/3146/1386 7 Yellow_fever_virus R-HSA-975871 MyD88 cascade initiated on plasma membrane 7/82 85/10654 3.756232125966592e-6 3.0333346224786822e-5 1.7456967576488234e-5 2353/4615/3725/4790/5970/3146/1386 7 Yellow_fever_virus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 4/82 15/10654 4.171509813849197e-6 3.306307778384178e-5 1.902793950176827e-5 54106/3665/4615/51284 4 Yellow_fever_virus R-HSA-447115 Interleukin-12 family signaling 6/82 57/10654 4.583003159918029e-6 3.56640973171803e-5 2.05248371181018e-5 3717/3586/6772/3458/7297/3716 6 Yellow_fever_virus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 5/82 34/10654 5.576758694447697e-6 4.262237002185026e-5 2.452935215226995e-5 64135/29110/57506/3661/23586 5 Yellow_fever_virus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 4/82 17/10654 7.188584633151958e-6 5.397744250857962e-5 3.106424384409157e-5 4615/7098/4790/5970 4 Yellow_fever_virus R-HSA-5621575 CD209 (DC-SIGN) signaling 4/82 21/10654 1.7658244072664128e-5 1.303056631569008e-4 7.499145395650466e-5 4790/1387/2033/5970 4 Yellow_fever_virus R-HSA-1169408 ISG15 antiviral mechanism 6/82 72/10654 1.8001841879650526e-5 1.3035496509889878e-4 7.501982743025655e-5 3434/6772/4599/3661/3716/23586 6 Yellow_fever_virus R-HSA-1433557 Signaling by SCF-KIT 5/82 43/10654 1.8274060527883004e-5 1.3035496509889878e-4 7.501982743025655e-5 3717/6772/8651/5781/5777 5 Yellow_fever_virus R-HSA-167161 HIV Transcription Initiation 5/82 47/10654 2.8427573303816222e-5 1.8159703543333346e-4 1.0450985315150033e-4 2962/2960/2959/2957/5430 5 Yellow_fever_virus R-HSA-167162 RNA Polymerase II HIV Promoter Escape 5/82 47/10654 2.8427573303816222e-5 1.8159703543333346e-4 1.0450985315150033e-4 2962/2960/2959/2957/5430 5 Yellow_fever_virus R-HSA-73776 RNA Polymerase II Promoter Escape 5/82 47/10654 2.8427573303816222e-5 1.8159703543333346e-4 1.0450985315150033e-4 2962/2960/2959/2957/5430 5 Yellow_fever_virus R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 5/82 47/10654 2.8427573303816222e-5 1.8159703543333346e-4 1.0450985315150033e-4 2962/2960/2959/2957/5430 5 Yellow_fever_virus R-HSA-75953 RNA Polymerase II Transcription Initiation 5/82 47/10654 2.8427573303816222e-5 1.8159703543333346e-4 1.0450985315150033e-4 2962/2960/2959/2957/5430 5 Yellow_fever_virus R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 5/82 47/10654 2.8427573303816222e-5 1.8159703543333346e-4 1.0450985315150033e-4 2962/2960/2959/2957/5430 5 Yellow_fever_virus R-HSA-9020591 Interleukin-12 signaling 5/82 47/10654 2.8427573303816222e-5 1.8159703543333346e-4 1.0450985315150033e-4 3717/3586/3458/7297/3716 5 Yellow_fever_virus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 6/82 80/10654 3.297085347988483e-5 2.075224307263339e-4 1.1943002653704413e-4 3434/6772/4599/3661/3716/23586 6 Yellow_fever_virus R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 4/82 25/10654 3.6458427438668474e-5 2.2614792672101604e-4 1.3014907735542982e-4 8850/6772/1387/2033 4 Yellow_fever_virus R-HSA-450341 Activation of the AP-1 family of transcription factors 3/82 10/10654 5.072370121043982e-5 3.035293603386407e-4 1.7468241593517444e-4 2353/3725/1386 3 Yellow_fever_virus R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 3/82 10/10654 5.072370121043982e-5 3.035293603386407e-4 1.7468241593517444e-4 8850/1387/2033 3 Yellow_fever_virus R-HSA-8939211 ESR-mediated signaling 9/82 223/10654 5.106101388874329e-5 3.035293603386407e-4 1.7468241593517444e-4 2962/2353/8850/3725/2957/1387/5430/2033/1386 9 Yellow_fever_virus R-HSA-2586552 Signaling by Leptin 3/82 11/10654 6.935792116627245e-5 4.066464419063645e-4 2.34026727511287e-4 3717/9021/5781 3 Yellow_fever_virus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 3/82 12/10654 9.196402529050195e-5 5.31900038166687e-4 3.0611069584605207e-4 64135/57506/23586 3 Yellow_fever_virus R-HSA-446652 Interleukin-1 family signaling 7/82 140/10654 9.735295303669864e-5 5.555608519960937e-4 3.197275931310525e-4 29110/4615/5781/5777/4790/5970/3146 7 Yellow_fever_virus R-HSA-1679131 Trafficking and processing of endosomal TLR 3/82 13/10654 1.1888997280385327e-4 6.695382678953842e-4 3.8532207252218374e-4 54106/7098/51284 3 Yellow_fever_virus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 5/82 65/10654 1.3737194529194122e-4 7.635739296746862e-4 4.394399890405229e-4 2962/2353/3725/5430/1386 5 Yellow_fever_virus R-HSA-8941856 RUNX3 regulates NOTCH signaling 3/82 14/10654 1.5047530013354883e-4 8.256849802199859e-4 4.7518515831647005e-4 8850/1387/2033 3 Yellow_fever_virus R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 6/82 110/10654 1.956640320712389e-4 0.0010600532370441803 6.100650700155885e-4 2353/3576/3725/4790/3569/5970 6 Yellow_fever_virus R-HSA-448424 Interleukin-17 signaling 5/82 72/10654 2.231175208326598e-4 0.0011936787364547298 6.869671036163474e-4 3605/2353/3725/4790/1386 5 Yellow_fever_virus R-HSA-193639 p75NTR signals via NF-kB 3/82 16/10654 2.289408852347855e-4 0.001194959742444978 6.877043279196381e-4 4615/4790/5970 3 Yellow_fever_virus R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 3/82 16/10654 2.289408852347855e-4 0.001194959742444978 6.877043279196381e-4 8850/1387/2033 3 Yellow_fever_virus R-HSA-167172 Transcription of the HIV genome 5/82 73/10654 2.3808981151079032e-4 0.0012277402328508223 7.065696372038674e-4 2962/2960/2959/2957/5430 5 Yellow_fever_virus R-HSA-6807505 RNA polymerase II transcribes snRNA genes 5/82 74/10654 2.53814788484373e-4 0.0012932467794203766 7.442689286383871e-4 2962/2960/2959/2957/5430 5 Yellow_fever_virus R-HSA-6788467 IL-6-type cytokine receptor ligand interactions 3/82 17/10654 2.76459235363707e-4 0.0013920535615960775 8.011326448929715e-4 3717/7297/3716 3 Yellow_fever_virus R-HSA-5683057 MAPK family signaling cascades 9/82 294/10654 4.114442090011332e-4 0.0020476525750288952 0.0011784326181917403 3717/60/3559/3563/7297/5781/3725/3569/3716 9 Yellow_fever_virus R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 3/82 20/10654 4.558186384339963e-4 0.0022030514366274834 0.0012678653127664319 8850/1387/2033 3 Yellow_fever_virus R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 5/82 84/10654 4.581111632239393e-4 0.0022030514366274834 0.0012678653127664319 7124/4790/1387/2033/5970 5 Yellow_fever_virus R-HSA-674695 RNA Polymerase II Pre-transcription Events 5/82 84/10654 4.581111632239393e-4 0.0022030514366274834 0.0012678653127664319 2962/2960/2959/2957/5430 5 Yellow_fever_virus R-HSA-9006931 Signaling by Nuclear Receptors 9/82 299/10654 4.65209308664419e-4 0.002212328712315237 0.001273204423713147 2962/2353/8850/3725/2957/1387/5430/2033/1386 9 Yellow_fever_virus R-HSA-9008059 Interleukin-37 signaling 3/82 21/10654 5.28845370827551e-4 0.002469122367912165 0.0014209902461668634 29110/5781/5777 3 Yellow_fever_virus R-HSA-9012852 Signaling by NOTCH3 4/82 49/10654 5.30745929551213e-4 0.002469122367912165 0.0014209902461668634 8850/6772/1387/2033 4 Yellow_fever_virus R-HSA-2559583 Cellular Senescence 7/82 195/10654 7.370997490122735e-4 0.0033922440062070223 0.0019522506085893833 2353/3576/3456/3725/4790/3569/5970 7 Yellow_fever_virus R-HSA-5684996 MAPK1/MAPK3 signaling 8/82 255/10654 7.455680732751478e-4 0.003394714205976205 0.001953672218884486 3717/60/3559/3563/7297/5781/3569/3716 8 Zaire_ebolavirus R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 252/1454 309/10654 1.511321757113159e-167 1.902754092205467e-164 1.092924260143937e-164 8454/9354/57154/197131/23352/26224/8945/10293/51088/140460/79754/6737/8065/64410/127544/114088/11065/285231/221687/9666/84937/57531/142678/55070/84708/246184/146330/55819/51320/93611/7319/54850/142686/8916/79791/26046/151636/7321/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/8697/7320/26235/10477/9817/10193/148581/9039/223082/92912/154881/140739/25897/6500/6478/150726/390594/10533/81559/144699/140462/26259/57674/51130/53339/154214/7336/200845/79876/26263/64750/51619/6477/9690/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/9604/9978/22888/23304/7317/80196/114907/140456/64718/54926/4008/7335/84861/11059/55236/84085/55958/54620/4734/84078/7337/26272/84676/27252/51444/7704/8651/3093/26118/222235/51433/25831/7322/64219/10489/23327/9867/26249/140458/55905/55336/26270/143279/51465/63893/89122/6502/23291/118424/10616/27246/89910/55521/25898/9903/201456/55294/26190/55008/7328/79654/10422/84727/135892/7428/22954/8453/401036/83737/51529/9040/90933/140461/7324/63891/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/6233/90135/56658/9870/51434/6468/26267/142685/4012/25847/90025/7327/10425/25793/51343/7311/26091/23295/6047/84541/7318/23194/51666/90293/131405/55175/55284/868/54461/9320/136371/80204/26232/29882/57520/26234/127247/27338/7334/92591/5930/11275/55182/84961/4591/23014/29116/26268/92369/115290/90678/51725/140459/997/23608/51676/55585/64320/51132/84261/7325/57542/9820/55658/7314/996/10324/283807/140691/899 252 Zaire_ebolavirus R-HSA-983169 Class I MHC mediated antigen processing & presentation 276/1454 371/10654 1.1762522179939947e-164 7.404507712272197e-162 4.253080388220391e-162 8454/9354/57154/1147/8773/197131/23352/26224/8945/10293/51088/140460/79754/6737/8065/64410/127544/114088/11065/285231/221687/9666/84937/57531/142678/55070/84708/246184/146330/55819/51320/93611/7319/54850/142686/8916/79791/26046/151636/3107/7321/991/11146/51665/84231/10273/255488/9616/65264/122769/91694/9021/8697/10484/7320/26235/10477/10802/9817/10193/148581/9039/223082/92912/154881/140739/821/25897/6500/6478/150726/390594/10533/81559/144699/140462/26259/57674/51130/10333/53339/7099/8517/154214/7336/200845/4615/79876/26263/64750/51619/6477/9690/9554/8881/8452/7326/23376/6049/7323/10517/57630/54778/89890/142689/7316/9604/9978/22888/23304/7317/80196/114907/140456/64718/54926/4008/7335/84861/7096/11059/567/55236/84085/55958/54620/4734/84078/7337/26272/84676/27252/51444/7704/8651/3093/26118/222235/51433/25831/7322/64219/10489/23327/9867/26249/140458/55905/55336/9341/26270/143279/51465/63893/89122/6502/23291/118424/10616/3309/27246/89910/55521/114609/25898/9903/201456/55294/26190/55008/7328/79654/10422/84727/135892/7428/22954/8453/401036/83737/51529/9040/90933/140461/7324/63891/10075/64682/29945/9246/10393/79176/80176/8139/8924/8925/51191/126433/6233/90135/56658/9870/51434/6468/26267/142685/4012/25847/90025/7327/3685/10425/25793/51343/7311/26091/23295/6047/84541/7318/23194/51666/90293/131405/55175/55284/868/54461/9320/136371/80204/26232/29882/57520/26234/6396/127247/27338/7334/92591/5930/11275/55182/7097/84961/4591/3551/8673/23014/29116/26268/92369/115290/90678/51725/140459/3105/997/23608/51676/55585/64320/51132/84261/7325/10427/57542/9820/55658/7314/996/4360/10324/283807/140691/899 276 Zaire_ebolavirus R-HSA-8951664 Neddylation 164/1454 234/10654 2.132976742300872e-89 8.951392395189327e-87 5.141596568283155e-87 8454/9318/51397/26224/54165/8945/56995/23412/51088/9655/140460/79754/8065/64410/149951/29099/285231/23038/146330/93611/54850/142686/55884/79791/7321/51665/9616/122769/9021/4738/26235/9817/9039/154881/140739/6500/150726/3091/390594/144699/140462/28952/55827/26259/51130/53339/28991/200845/332/26263/140825/8452/8450/7323/9306/10517/89890/142689/7316/50717/9978/114907/140456/4008/84861/64708/84085/55958/54620/84078/55527/26272/27252/7704/1643/26118/222235/10980/7322/122416/10489/26249/140458/55336/26270/6502/7347/23291/170622/90864/55832/1642/10920/9903/201456/55294/26190/84727/10987/7428/8453/123879/401036/9040/140461/79176/80176/8139/23142/126433/10116/26043/6233/90135/6468/2873/26267/142685/25793/7311/1154/84541/23194/51666/2034/90293/55175/8533/54461/136371/80204/26232/8835/26234/127247/8883/92591/11275/51122/84961/54939/23014/26268/92369/115290/54951/51725/140459/55208/84259/51676/84261/150684/50813/57542/9820/7314/10537/51138/10324/8451/56929/283807/899 164 Zaire_ebolavirus R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 68/1454 78/10654 1.216243454574436e-48 3.828126273273037e-46 2.1988401402437827e-46 1147/3443/3665/3441/351/7186/4790/80143/7321/8737/9140/29110/57506/79132/4214/9636/54476/3449/841/7706/8517/3444/84166/7323/9474/7316/5970/4792/4793/3093/3146/23586/7322/7128/1387/3451/843/3448/2033/64135/3440/54941/83737/3661/9246/7189/6285/51191/6233/10010/7311/55593/84282/7318/79671/5094/7187/8772/5300/3452/9641/1540/3551/3456/4791/3446/7314/3445 68 Zaire_ebolavirus R-HSA-913531 Interferon Signaling 113/1454 199/10654 2.4472841825402993e-47 6.162261571636474e-45 3.539545754537232e-45 3839/3443/23165/3665/3460/5777/3837/3838/81929/3441/5903/6737/10379/402569/5335/55706/7175/960/5770/9631/3107/2633/9021/85363/54739/9830/4600/348995/9636/79023/2537/57122/23636/11274/8638/3449/25820/7706/3444/10762/23511/4684/7316/53371/567/4734/3434/6672/6772/8651/23279/4927/9688/3433/3659/79902/23586/8672/6041/3840/3459/9883/4939/7341/3451/3717/23225/3448/1981/3440/5771/10612/3458/3454/3661/8086/7324/3836/9246/5371/51191/4599/6233/684/3716/7311/81603/9972/7318/5610/5300/8021/3452/4940/91543/6396/3437/129401/7334/3456/6773/4938/7297/5781/3430/55746/3105/3446/8480/7314/3445/5595/8554 113 Zaire_ebolavirus R-HSA-2990846 SUMOylation 107/1454 188/10654 5.610773867789348e-45 1.1773273832577984e-42 6.762459030125056e-43 1912/10054/23165/23468/5905/81929/5893/286053/5903/7068/29843/55706/7175/1487/55143/9631/5468/1029/7486/9112/8535/6045/9212/51588/3619/4869/80012/7153/348995/51602/79023/6613/57122/23636/8517/332/3183/10762/23511/4929/28996/53371/5970/4792/3190/6996/9759/1911/641/23137/6672/5111/23279/4927/9688/79902/9656/9883/7341/1387/84733/10401/1616/23225/2908/10055/59343/2033/165918/57332/142/7428/3066/3065/23314/7157/1107/1069/8086/7329/5987/5371/7376/8924/672/7158/9972/6612/9063/8021/9641/6117/7690/6294/6396/129401/7703/55746/6304/4791/8480/7508/6015/4193/8554/79677/205564 107 Zaire_ebolavirus R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 102/1454 182/10654 4.605880653107055e-42 8.28400534608826e-40 4.7582556521572124e-40 1912/23165/23468/5905/81929/5893/286053/5903/7068/55706/7175/1487/55143/9631/5468/1029/7486/9112/8535/6045/9212/51588/3619/4869/80012/7153/348995/51602/79023/6613/57122/23636/8517/332/3183/10762/23511/4929/28996/53371/5970/4792/3190/6996/9759/1911/641/23137/6672/5111/23279/4927/9688/79902/9656/9883/7341/1387/84733/10401/1616/23225/2908/2033/165918/57332/142/7428/3066/3065/23314/7157/1107/1069/8086/7329/5987/5371/7376/8924/672/7158/9972/6612/9063/8021/9641/6117/7690/6294/6396/129401/7703/55746/6304/4791/8480/7508/6015/4193/8554/79677 102 Zaire_ebolavirus R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 64/1454 80/10654 3.8298884066141103e-41 6.027286879908957e-39 3.4620175465051236e-39 3839/23165/3837/3838/81929/5903/402569/5335/55706/7175/9631/4600/348995/9636/79023/57122/23636/11274/8638/25820/7706/10762/23511/7316/53371/4734/3434/6772/23279/4927/9688/79902/23586/8672/6041/3840/9883/4939/23225/1981/3661/8086/7324/3836/9246/51191/4599/6233/3716/7311/9972/7318/5610/5300/8021/4940/6396/129401/7334/4938/55746/8480/7314/5595 64 Zaire_ebolavirus R-HSA-73894 DNA Repair 142/1454 334/10654 8.329612617857357e-40 1.1652202539869347e-37 6.692916805225737e-38 9318/6118/2176/80010/25/3838/2237/6917/5893/2178/4436/83990/5888/5892/9156/1763/328/27339/7486/5430/56852/7320/51588/675/2956/404672/9557/4292/9636/11200/545/472/6613/7507/7706/80198/7336/51567/3981/580/11073/2072/8450/353497/54778/7316/9978/116028/197342/6996/64708/641/79008/5111/1643/10459/2966/7415/7517/10980/9656/6119/84464/51455/3364/7341/5437/10401/5889/9937/2177/1642/2965/10920/25898/2033/165918/29089/84126/142/7398/2068/1111/10987/2071/7157/55215/23514/1069/7329/9246/79728/64858/8924/57599/6233/2067/2873/548593/2968/146956/672/7158/7311/6047/9025/2189/7318/55120/2967/2187/6612/8533/7156/8607/5890/5887/6117/2175/2073/5599/7334/5981/10038/7874/2547/5884/5810/348654/2188/5886/4437/55183/50813/5980/57697/7508/7314/22909/51138/8451/8554 142 Zaire_ebolavirus R-HSA-1169408 ISG15 antiviral mechanism 59/1454 72/10654 3.868024698050693e-39 4.869843094845823e-37 2.797192597432448e-37 3839/23165/3837/3838/81929/5903/402569/5335/55706/7175/9631/4600/348995/9636/79023/57122/23636/11274/25820/7706/10762/23511/7316/53371/4734/3434/6772/23279/4927/9688/79902/23586/8672/3840/9883/23225/1981/3661/8086/7324/3836/9246/51191/4599/6233/3716/7311/9972/7318/5610/5300/8021/6396/129401/7334/55746/8480/7314/5595 59 Zaire_ebolavirus R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 60/1454 77/10654 2.0242051495839543e-37 2.3167948030238167e-35 1.3307453949896427e-35 1912/23165/81929/5893/286053/5903/55706/7175/9631/1029/7486/8535/6045/51588/80012/348995/79023/6613/57122/23636/10762/23511/53371/6996/1911/641/23137/6672/23279/4927/9688/79902/9656/9883/7341/84733/23225/165918/57332/142/1069/8086/7329/5371/8924/672/9972/6612/9063/8021/6117/6396/129401/7703/55746/8480/7508/6015/8554/79677 60 Zaire_ebolavirus R-HSA-5696395 Formation of Incision Complex in GG-NER 39/1454 43/10654 8.383778429996528e-30 8.795980869471358e-28 5.052329632813697e-28 6118/404672/9557/6613/7507/7336/2072/8450/54778/7316/9978/1643/2966/6119/7341/10401/1642/2965/142/2068/2071/1069/7329/6233/2067/2968/7311/2967/6612/5887/6117/2073/7334/10038/5886/7508/7314/8451/8554 39 Zaire_ebolavirus R-HSA-4570464 SUMOylation of RNA binding proteins 41/1454 47/10654 9.805431964406739e-30 9.496183725529295e-28 5.454519643358242e-28 1912/23165/81929/5903/55706/7175/9631/8535/6045/80012/348995/51602/79023/6613/57122/23636/3183/10762/23511/53371/3190/1911/23279/4927/9688/79902/9883/7341/84733/23225/57332/8086/7329/9972/8021/6396/129401/7703/55746/8480/6015 41 Zaire_ebolavirus R-HSA-4615885 SUMOylation of DNA replication proteins 39/1454 45/10654 4.1884622052280446e-028 3.76662422598722e-26 2.16351393608396e-26 23165/5905/81929/5903/55706/7175/55143/9631/9212/51588/3619/7153/348995/79023/6613/57122/23636/332/10762/23511/53371/5111/23279/4927/9688/79902/9883/7341/10401/23225/8086/7329/9972/6612/8021/6396/129401/55746/8480 39 Zaire_ebolavirus R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 33/1454 34/10654 6.171987448323423e-28 5.180354798292793e-26 2.9755476329811863e-26 7321/9140/29110/57506/9636/54476/7706/84166/7323/9474/7316/3093/23586/7322/7128/64135/54941/83737/3661/9246/51191/6233/7311/55593/84282/7318/79671/5094/7187/5300/9641/1540/7314 33 Zaire_ebolavirus R-HSA-3232142 SUMOylation of ubiquitinylation proteins 35/1454 38/10654 2.0738237347945655e-27 1.6318400513164738e-25 9.373137538183333e-26 23165/81929/5903/55706/7175/9631/51588/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/7341/23225/7428/8086/7329/5987/5371/9972/9063/8021/6396/129401/55746/8480/4193/8554 35 Zaire_ebolavirus R-HSA-177243 Interactions of Rev with host cellular proteins 33/1454 36/10654 9.813718099445648e-26 7.267924168942394e-24 4.174628070785857e-24 23165/5905/3837/81929/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5902/5901/8086/7514/9972/8021/6396/129401/1104/55746/8480 33 Zaire_ebolavirus R-HSA-4551638 SUMOylation of chromatin organization proteins 48/1454 71/10654 1.6643044923587317e-25 1.1640885310442462e-23 6.686416293862273e-24 1912/23165/23468/81929/5903/55706/7175/9631/8535/6045/80012/348995/79023/6613/57122/23636/10762/23511/53371/9759/1911/23279/4927/9688/79902/9883/7341/84733/23225/57332/3066/3065/23314/1107/8086/7329/9972/6612/9063/8021/6396/129401/7703/55746/6304/8480/6015/8554 48 Zaire_ebolavirus R-HSA-2980766 Nuclear Envelope Breakdown 40/1454 52/10654 6.135579659836242e-25 4.065628837754646e-23 2.3352594051565084e-23 4000/23165/81929/5903/55706/7175/5579/9631/5578/140609/10783/348995/79023/9133/57122/23636/10762/23511/891/53371/983/23279/4927/9688/79902/9883/23225/7444/8086/2010/4001/23592/9972/5347/8021/6396/129401/55746/7112/8480 40 Zaire_ebolavirus R-HSA-165054 Rev-mediated nuclear export of HIV RNA 31/1454 34/10654 4.5878677289547775e-24 2.6607989908590116e-22 1.5283382021823008e-22 23165/5905/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5902/5901/8086/7514/9972/8021/6396/129401/1104/55746/8480 31 Zaire_ebolavirus R-HSA-168276 NS1 Mediated Effects on Host Pathways 34/1454 40/10654 4.649529610714715e-24 2.6607989908590116e-22 1.5283382021823008e-22 3839/23165/3837/3838/81929/5903/402569/55706/7175/9631/348995/9636/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/3840/9883/23225/8086/3836/9972/5610/8021/6396/129401/55746/8480 34 Zaire_ebolavirus R-HSA-6783310 Fanconi Anemia Pathway 34/1454 40/10654 4.649529610714715e-24 2.6607989908590116e-22 1.5283382021823008e-22 6118/2176/2178/545/80198/2072/353497/7316/197342/79008/6119/84464/9937/2177/29089/84126/7398/55215/64858/57599/6233/2067/548593/146956/7311/2189/55120/2187/6117/2175/2188/57697/7314/22909 34 Zaire_ebolavirus R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 51/1454 84/10654 8.955671353395798e-24 4.902256623445787e-22 2.815810626902935e-22 9318/6118/404672/9557/6613/7507/7336/2072/8450/54778/7316/9978/64708/5111/1643/2966/10980/6119/7341/10401/1642/2965/10920/142/2068/10987/2071/1069/7329/6233/2067/2873/2968/7311/2967/6612/8533/8607/5887/6117/2073/7334/5981/10038/5886/50813/7508/7314/51138/8451/8554 51 Zaire_ebolavirus R-HSA-180746 Nuclear import of Rev protein 30/1454 33/10654 3.121459203256609e-23 1.6374654737083628e-21 9.405449441391624e-22 23165/3837/81929/5903/55706/7175/9631/4869/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/9972/8021/6396/129401/1104/55746/8480 30 Zaire_ebolavirus R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 31/1454 35/10654 3.4935313206441877e-23 1.759342373076413e-21 1.010549902013708e-21 23165/81929/5903/55706/7175/9631/140609/10783/348995/79023/9133/57122/23636/10762/23511/891/53371/983/23279/4927/9688/79902/9883/23225/8086/9972/8021/6396/129401/55746/8480 31 Zaire_ebolavirus R-HSA-168253 Host Interactions with Influenza Factors 34/1454 42/10654 1.082508000076077e-22 5.2418368157530026e-21 3.010862332195404e-21 3839/23165/3837/3838/81929/5903/402569/55706/7175/9631/348995/9636/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/3840/9883/23225/8086/3836/9972/5610/8021/6396/129401/55746/8480 34 Zaire_ebolavirus R-HSA-4085377 SUMOylation of SUMOylation proteins 30/1454 34/10654 2.3091502430965084e-22 1.076748205947594e-20 6.1847415867731045e-21 23165/81929/5903/55706/7175/9631/51588/348995/79023/6613/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/7341/23225/8086/7329/9972/8021/6396/129401/55746/8480 30 Zaire_ebolavirus R-HSA-909733 Interferon alpha/beta signaling 44/1454 69/10654 6.33842338310626e-22 2.8500267997609935e-20 1.6370288963135337e-20 3443/3665/5777/3441/10379/5770/3107/9021/54739/4600/9636/2537/11274/8638/3449/3444/3434/6772/8651/3433/3659/6041/4939/3451/3448/3440/3454/3661/4599/684/3716/3452/4940/91543/3437/3456/6773/4938/7297/5781/3430/3105/3446/3445 44 Zaire_ebolavirus R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 28/1454 31/10654 1.4295273480230946e-21 5.99924977053692e-20 3.445913291550407e-20 23165/3837/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/3836/9972/8021/6396/129401/55746/8480 28 Zaire_ebolavirus R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 28/1454 31/10654 1.4295273480230946e-21 5.99924977053692e-20 3.445913291550407e-20 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/7514/9972/8021/6396/129401/55746/8480 28 Zaire_ebolavirus R-HSA-5696398 Nucleotide Excision Repair 57/1454 111/10654 1.982493164947213e-21 8.05148030538239e-20 4.6246954306238884e-20 9318/6118/6917/27339/5430/404672/9557/6613/7507/7336/2072/8450/54778/7316/9978/64708/5111/1643/2966/10980/6119/7341/5437/10401/1642/2965/10920/2033/142/2068/10987/2071/1069/7329/6233/2067/2873/2968/7311/2967/6612/8533/8607/5887/6117/2073/7334/5981/10038/7874/5886/50813/7508/7314/51138/8451/8554 57 Zaire_ebolavirus R-HSA-449147 Signaling by Interleukins 139/1454 461/10654 3.5798606648778764e-21 1.4084514303378896e-19 8.09001406832599e-20 5295/729230/8454/3605/7124/1147/834/7291/5777/8945/9655/351/3592/3566/1437/3667/4790/6627/6885/6597/9049/3561/3587/5783/7184/3593/6775/3684/9021/29110/3553/1439/8878/3595/821/6500/5908/3091/8517/6657/6778/4615/7534/332/3597/6776/3688/2357/1436/7316/3565/9978/3560/79155/6774/1435/7335/5970/4792/1441/1026/3718/1440/4793/3627/6772/8651/4609/3146/7867/149233/64127/8503/867/3558/4067/3717/23291/836/3320/2534/5771/3458/998/7157/5478/942/4001/3563/7189/6285/5609/6233/2885/7525/1398/7006/6844/3716/84639/7409/8660/2353/6196/7311/3594/1154/6347/3932/3575/4507/2185/6845/5896/5296/3687/51561/3570/8835/5599/5600/7431/6777/7334/5008/3312/1399/3559/3551/6773/7297/5781/3569/3586/4791/7314/3572/5595/3556 139 Zaire_ebolavirus R-HSA-159227 Transport of the SLBP independent Mature mRNA 29/1454 34/10654 8.994302527114235e-21 3.431462691405097e-19 1.9710002667073299e-19 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10482/8086/9972/8021/6396/129401/55746/22916/8480 29 Zaire_ebolavirus R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 27/1454 30/10654 9.618509751861884e-21 3.561677581645327e-19 2.0457944890183013e-19 90268/11065/7319/7321/65264/7320/10477/92912/7326/7316/7317/54926/55236/3093/7322/7347/29089/7328/7324/6233/7327/7311/55284/27338/7874/997/7314 27 Zaire_ebolavirus R-HSA-5685942 HDR through Homologous Recombination (HRR) 42/1454 67/10654 1.4441388742546895e-20 5.194773836247583e-19 2.983829794324727e-19 6118/80010/83990/5888/5892/9156/1763/7486/675/545/472/80198/580/11073/7316/116028/197342/641/79008/5111/7517/6119/84464/3364/5889/84126/1111/23514/79728/6233/548593/146956/672/7311/7156/5890/6117/5981/5884/5810/348654/7314 42 Zaire_ebolavirus R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 29/1454 35/10654 4.5667263835342866e-20 1.597085699130463e-18 9.17351177043291e-19 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10482/8086/9972/8021/6396/129401/55746/22916/8480 29 Zaire_ebolavirus R-HSA-168274 Export of Viral Ribonucleoproteins from Nucleus 28/1454 33/10654 5.719166855632679e-20 1.9460624516869035e-18 1.117800179180555e-18 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/7514/9972/8021/6396/129401/55746/8480 28 Zaire_ebolavirus R-HSA-933541 TRAF6 mediated IRF7 activation 26/1454 29/10654 6.445028436849077e-20 2.1353396847349966e-18 1.226519262081805e-18 3443/3665/3441/7186/80143/29110/57506/3449/7706/3444/23586/1387/3451/3448/2033/64135/3440/3661/7189/10010/84282/3452/9641/3456/3446/3445 26 Zaire_ebolavirus R-HSA-2262752 Cellular responses to stress 139/1454 479/10654 1.6749384748174341e-19 5.407044973833717e-18 3.105756362212084e-18 1912/23165/6118/81929/55846/5903/11065/4790/55706/7175/54468/9631/246184/112399/7531/1029/7027/11133/23334/7321/2146/79726/8535/6045/8697/3308/1027/27327/80012/898/3091/348995/1410/10013/545/79023/472/10381/57122/23636/9681/10762/8881/23511/7323/7316/9978/53371/527/6774/5970/1026/1911/6667/525/23279/4927/9688/10121/7415/7867/51433/79902/7322/6119/9883/5928/1387/84733/84219/7846/259217/23225/3310/2908/3309/347733/3320/2033/57332/10376/6009/3301/25994/7428/7157/8453/51529/8086/23135/7324/10963/4001/64682/29945/10393/5609/8131/6233/2056/51434/2475/55004/2353/51343/6196/7311/9972/538/2034/10383/23411/8021/4343/6117/29882/5599/6396/129401/5600/3312/4217/3456/405/3569/3297/57521/55746/10641/7280/8480/7314/996/6015/28956/5595/4193/9296/23043 139 Zaire_ebolavirus R-HSA-3371556 Cellular response to heat stress 48/1454 89/10654 2.03732908475321e-19 6.4124932942607284e-018 3.683276529540671e-18 23165/6118/81929/5903/55706/7175/9631/7531/3308/348995/1410/10013/545/79023/472/57122/23636/10762/23511/53371/23279/4927/9688/7415/79902/6119/9883/1387/259217/23225/3310/3309/3320/2033/8086/2475/9972/23411/8021/6117/6396/129401/3312/3297/57521/55746/8480/5595 48 Zaire_ebolavirus R-HSA-5693532 DNA Double-Strand Break Repair 69/1454 166/10654 4.0355085389773314e-19 1.2391964025786488e-17 7.117828924974138e-18 6118/80010/25/3838/2237/5893/83990/5888/5892/9156/1763/7486/51588/675/11200/545/472/6613/80198/7336/51567/3981/580/11073/2072/7316/116028/197342/641/79008/5111/7517/9656/6119/84464/3364/7341/5889/165918/84126/142/1111/7157/23514/7329/79728/8924/6233/2067/548593/146956/672/7158/7311/6047/9025/7156/5890/6117/5599/7334/5981/10038/2547/5884/5810/348654/55183/7314 69 Zaire_ebolavirus R-HSA-168898 Toll-like Receptor Cascades 66/1454 155/10654 5.235342282950712e-19 1.5693561748178442e-17 9.014235960870022e-18 54106/8454/1147/3665/8945/351/81793/4790/6885/7184/7321/8737/3684/29110/4214/6500/8411/6280/10333/841/7099/8517/4615/7098/7100/7323/7316/79155/7335/5970/4792/7096/4793/8651/26052/3146/7867/7322/64127/23291/114609/3661/7189/6285/5609/6233/51311/10010/2353/6196/7311/7187/8772/9641/5599/5600/7334/7097/3551/5781/4791/1508/51284/7314/5595/148022 66 Zaire_ebolavirus R-HSA-5693538 Homology Directed Repair 61/1454 138/10654 1.2264840014743979e-18 3.591031064782016e-17 2.0626548568247524e-17 6118/80010/25/2237/5893/83990/5888/5892/9156/1763/7486/51588/675/545/472/6613/80198/7336/580/11073/2072/7316/116028/197342/641/79008/5111/7517/9656/6119/84464/3364/7341/5889/165918/84126/142/1111/23514/7329/79728/8924/6233/2067/548593/146956/672/7158/7311/6047/9025/7156/5890/6117/7334/5981/10038/5884/5810/348654/7314 61 Zaire_ebolavirus R-HSA-180910 Vpr-mediated nuclear import of PICs 27/1454 33/10654 1.7312536036994622e-18 4.953746106949143e-17 2.845385707515623e-17 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/3836/9972/8021/6396/129401/55746/8480 27 Zaire_ebolavirus R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 26/1454 31/10654 2.271862747050347e-18 6.217989562035624e-17 3.571555394104321e-17 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/6396/129401/55746/8480 26 Zaire_ebolavirus R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 26/1454 31/10654 2.271862747050347e-18 6.217989562035624e-17 3.571555394104321e-17 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/8086/9972/8021/6396/129401/55746/8480 26 Zaire_ebolavirus R-HSA-8953897 Cellular responses to external stimuli 139/1454 493/10654 2.7442761337901746e-18 7.351156707323042e-17 4.222436066996304e-17 1912/23165/6118/81929/55846/5903/11065/4790/55706/7175/54468/9631/246184/112399/7531/1029/7027/11133/23334/7321/2146/79726/8535/6045/8697/3308/1027/27327/80012/898/3091/348995/1410/10013/545/79023/472/10381/57122/23636/9681/10762/8881/23511/7323/7316/9978/53371/527/6774/5970/1026/1911/6667/525/23279/4927/9688/10121/7415/7867/51433/79902/7322/6119/9883/5928/1387/84733/84219/7846/259217/23225/3310/2908/3309/347733/3320/2033/57332/10376/6009/3301/25994/7428/7157/8453/51529/8086/23135/7324/10963/4001/64682/29945/10393/5609/8131/6233/2056/51434/2475/55004/2353/51343/6196/7311/9972/538/2034/10383/23411/8021/4343/6117/29882/5599/6396/129401/5600/3312/4217/3456/405/3569/3297/57521/55746/10641/7280/8480/7314/996/6015/28956/5595/4193/9296/23043 139 Zaire_ebolavirus R-HSA-176033 Interactions of Vpr with host cellular proteins 28/1454 36/10654 4.810035211384752e-18 1.261632152319459e-16 7.24669778557308e-17 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/292/23279/4927/9688/79902/9883/23225/8086/3836/9972/8021/6396/129401/55746/8480 28 Zaire_ebolavirus R-HSA-3371453 Regulation of HSF1-mediated heat shock response 40/1454 69/10654 6.614209153069008e-18 1.6994468007579349e-16 9.761464421392928e-17 23165/6118/81929/5903/55706/7175/9631/7531/3308/348995/545/79023/472/57122/23636/10762/23511/53371/23279/4927/9688/79902/6119/9883/259217/23225/3310/3309/8086/9972/23411/8021/6117/6396/129401/3312/3297/55746/8480/5595 40 Zaire_ebolavirus R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 58/1454 132/10654 1.2377323969854487e-17 3.11661017560936e-16 1.7901519089031643e-16 6118/80010/25/5893/83990/5888/5892/9156/1763/7486/51588/675/545/472/6613/80198/7336/580/11073/2072/7316/116028/197342/641/79008/5111/7517/9656/6119/84464/3364/7341/5889/165918/84126/1111/23514/7329/79728/8924/6233/2067/548593/146956/672/7158/7311/6047/9025/7156/5890/6117/7334/5981/5884/5810/348654/7314 58 Zaire_ebolavirus R-HSA-5693568 Resolution of D-loop Structures through Holliday Junction Intermediates 26/1454 33/10654 4.3304461552484955e-17 1.0690258253838933e-15 6.140384950785792e-16 80010/83990/5888/5892/9156/1763/7486/675/472/80198/580/116028/197342/641/79008/7517/84464/5889/23514/79728/548593/146956/672/7156/5890/348654 26 Zaire_ebolavirus R-HSA-69620 Cell Cycle Checkpoints 95/1454 293/10654 5.100243569308353e-17 1.2348474334152339e-15 7.092848850434895e-16 6118/5905/80010/81929/5903/5000/83990/11065/55143/9156/246184/9735/1763/7531/1029/7486/7321/991/7532/8317/10971/8697/9212/51588/1027/3619/898/7533/2810/348995/4173/11200/545/79023/9133/472/57122/7336/7534/332/580/8881/11073/7316/891/993/5501/116028/983/1026/641/4171/23279/51433/79902/9656/6119/3364/7341/1062/22919/990/165918/84126/4175/1111/7157/51529/7324/64682/29945/10393/8924/6233/51434/672/7514/7158/7311/9025/5347/7156/6117/29882/6396/7334/5001/5884/5810/55746/4176/7529/7314/996/4193 95 Zaire_ebolavirus R-HSA-1433557 Signaling by SCF-KIT 30/1454 43/10654 5.2198476596126613e-17 1.2399600383872342e-15 7.122215178061366e-16 5295/5777/4893/3815/10019/5578/6776/9306/6774/6772/6714/8651/8503/867/4067/3717/2534/1111/2885/7525/7006/7409/3932/4254/5296/3845/6777/3265/5781/5879 30 Zaire_ebolavirus R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 56/1454 129/10654 8.854114544228752e-17 2.0643204094785183e-15 1.1857264506598738e-15 8454/1147/3665/8945/351/4790/6885/7321/8737/3684/29110/4214/6500/10333/841/7099/8517/4615/7323/7316/79155/7335/5970/4792/7096/4793/8651/26052/3146/7867/7322/64127/23291/114609/3661/7189/6285/5609/6233/10010/2353/6196/7311/7187/8772/9641/5599/5600/7334/7097/3551/5781/4791/7314/5595/148022 56 Zaire_ebolavirus R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 29/1454 41/10654 9.665798074532761e-17 2.212589050152136e-15 1.2708905793691877e-15 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10482/8086/9972/8021/6396/129401/55746/22916/8480 29 Zaire_ebolavirus R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 21/1454 23/10654 1.161867371566981e-16 2.612126822862195e-15 1.5003813614032257e-15 11065/246184/7321/991/8697/8881/7316/891/983/51433/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 21 Zaire_ebolavirus R-HSA-5693537 Resolution of D-Loop Structures 26/1454 34/10654 1.6025137118320314e-16 3.539587303853557e-15 2.0331060388339898e-15 80010/83990/5888/5892/9156/1763/7486/675/472/80198/580/116028/197342/641/79008/7517/84464/5889/23514/79728/548593/146956/672/7156/5890/348654 26 Zaire_ebolavirus R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 46/1454 94/10654 1.745947002174761e-16 3.7899090961000415e-15 2.176888548991036e-15 8454/1147/3665/8945/351/4790/6885/7321/8737/29110/6500/841/8517/7098/7323/7316/79155/7335/5970/4792/4793/3146/7867/7322/64127/23291/3661/7189/6285/5609/6233/10010/2353/6196/7311/7187/8772/9641/5599/5600/7334/3551/4791/7314/5595/148022 46 Zaire_ebolavirus R-HSA-3700989 Transcriptional Regulation by TP53 109/1454 365/10654 1.9046683288593957e-16 4.064368518701659e-15 2.3345354896099997e-15 23774/834/6118/2176/5170/80010/27161/6917/4436/83990/5892/9156/1763/7531/1029/7027/7486/5430/9219/7532/10971/55240/22974/9212/1027/4869/404672/27327/898/7533/2810/4292/11200/545/472/8794/7534/332/580/11073/7316/891/28996/116028/80196/1457/983/1026/641/5111/1643/8148/2966/9656/6119/5928/3364/1387/5437/57459/1616/843/2177/2965/54815/2033/84126/5728/6009/8738/2068/1111/3066/3065/2071/7157/1107/55215/8626/5371/6233/2968/2475/55004/672/2353/7311/2967/6880/5300/7156/4343/6117/5600/904/4697/7874/2744/5884/5810/53615/10397/57521/5875/7529/7314/253260/28956/4193 109 Zaire_ebolavirus R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts 29/1454 42/10654 2.718343242132856e-16 5.703990236408777e-15 3.2763189602548634e-15 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10482/8086/9972/8021/6396/129401/55746/22916/8480 29 Zaire_ebolavirus R-HSA-166166 MyD88-independent TLR4 cascade 47/1454 99/10654 3.733871209800325e-16 7.582167505062272e-15 4.355126521447916e-15 8454/1147/3665/8945/351/4790/6885/7321/8737/29110/6500/841/7099/8517/7323/7316/79155/7335/5970/4792/4793/3146/7867/7322/64127/23291/3661/7189/6285/5609/6233/10010/2353/6196/7311/7187/8772/9641/5599/5600/7334/3551/5781/4791/7314/5595/148022 47 Zaire_ebolavirus R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 47/1454 99/10654 3.733871209800325e-16 7.582167505062272e-15 4.355126521447916e-15 8454/1147/3665/8945/351/4790/6885/7321/8737/29110/6500/841/7099/8517/7323/7316/79155/7335/5970/4792/4793/3146/7867/7322/64127/23291/3661/7189/6285/5609/6233/10010/2353/6196/7311/7187/8772/9641/5599/5600/7334/3551/5781/4791/7314/5595/148022 47 Zaire_ebolavirus R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 31/1454 48/10654 4.654332098347581e-16 9.301276367967626e-15 5.342566669281182e-15 5295/5777/1437/3561/1439/7534/6776/7316/3560/3718/8503/867/3558/4067/3717/2534/3563/6233/2885/7525/1398/7006/3716/7409/7311/5296/6777/1399/3559/5781/7314 31 Zaire_ebolavirus R-HSA-912694 Regulation of IFNA signaling 22/1454 26/10654 7.020113976369567e-16 1.3809880462889507e-14 7.9322669436939e-15 3443/5777/3441/5770/9021/11274/3449/3444/6772/8651/3451/3448/3440/3454/3716/3452/3456/6773/7297/5781/3446/3445 22 Zaire_ebolavirus R-HSA-5696400 Dual Incision in GG-NER 28/1454 41/10654 1.4004073027827979e-15 2.7124812218516036e-14 1.5580239951607807e-14 6118/404672/9557/7507/2072/8450/7316/9978/5111/1643/2966/6119/1642/2965/142/2068/2071/6233/2067/2968/7311/2967/6117/2073/5981/10038/7314/8451 28 Zaire_ebolavirus R-HSA-162587 HIV Life Cycle 60/1454 152/10654 1.5553812149102965e-15 2.9670074993516107e-14 1.704221522557215e-14 23165/5905/2237/6917/81929/5903/7852/55706/7175/9631/5430/404672/348995/79023/57122/23636/3981/10762/23511/4686/7316/53371/4836/23279/4927/9688/8148/2966/8731/79902/23327/9883/5437/23225/2965/2068/2071/5902/5901/8086/5478/3836/6233/2968/7514/7311/9972/2967/6880/8021/7251/6396/129401/904/1104/2547/55746/22916/8480/7314 60 Zaire_ebolavirus R-HSA-6798695 Neutrophil degranulation 129/1454 480/10654 3.1340647699968136e-15 5.889235142426848e-14 3.382721911999703e-14 2717/10694/8773/2512/23352/80331/5777/3837/23412/10890/7276/4893/5284/29099/9218/4790/327/960/7305/10159/3107/5315/203068/8876/5175/1650/3684/79888/10120/353189/4680/5908/6727/127829/258010/10533/29108/23385/3958/55754/4257/6280/5788/23317/326624/6993/2357/25852/10576/1509/4718/2896/4126/8895/5611/84061/527/5547/9545/1315/567/102/154664/54918/7415/3146/4353/2548/11010/6793/3920/9342/6836/226/197/8904/3310/55832/968/3320/3482/3614/25798/1088/10043/23200/150372/9961/5478/374395/10075/5878/2683/56729/684/10857/55004/6093/3916/3685/719/47/9522/10383/3687/10396/9145/5236/3608/7097/3312/64114/2040/5660/2547/8673/10493/8987/10970/401258/5663/7879/4758/1654/1508/967/22931/5879/28956 129 Zaire_ebolavirus R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 28/1454 42/10654 3.6575532599218616e-15 6.771852285649447e-14 3.889688993136716e-14 6118/80010/83990/5888/5892/9156/1763/7486/675/545/472/580/11073/116028/641/7517/6119/3364/5889/84126/1111/79728/672/7156/5890/6117/5884/5810 28 Zaire_ebolavirus R-HSA-168325 Viral Messenger RNA Synthesis 28/1454 43/10654 9.128303329124821e-15 1.665584621937413e-13 9.566963214506105e-14 23165/81929/5903/55706/7175/9631/5430/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/5437/23225/8086/9972/8021/6396/129401/55746/8480 28 Zaire_ebolavirus R-HSA-5688426 Deubiquitination 91/1454 297/10654 1.1892367789065111e-14 2.1389272923475677e-13 1.2285799505395082e-13 9960/7186/645836/6885/6314/10474/7321/991/8737/4738/7375/9817/57506/100287364/91833/409/6478/1080/3091/100287513/11274/4287/27005/7706/8517/64750/580/7316/993/79155/4792/9986/983/84132/8678/1643/4609/7415/392188/23586/100287144/27430/100287441/64127/7128/3416/9097/7046/6502/7347/9146/2033/408/64135/5728/8724/100287327/7157/9929/9958/4087/63891/7189/57599/6233/377630/672/100287478/7311/55593/84282/114548/78990/7187/23770/728386/8607/5887/7345/1540/29761/7874/100287404/154/10254/100287178/5886/100287205/7314/4193/100287238 91 Zaire_ebolavirus R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 126/1454 473/10654 1.389274099689441e-14 2.463515621843671e-13 1.4150204692166727e-13 5295/54106/3675/26999/5170/5777/1173/3643/5590/4893/8065/857/2670/3667/5335/558/5579/5770/1495/1499/5747/4690/3815/10006/5430/10273/10019/10458/5578/10193/2322/3315/5908/3178/10817/23385/2064/5921/6778/6776/9306/3688/4686/7316/1500/5753/9611/9047/527/6774/11059/57498/4233/102/4734/10413/10152/525/6772/6714/8651/26052/7867/3673/8503/23545/2261/867/5437/4067/3717/4914/9146/3320/2534/9475/8471/5771/1445/1111/3630/998/83737/7072/6285/6233/2885/7525/1398/5867/7410/7006/2475/7409/5900/8660/6093/3685/163/6196/7311/3932/3479/5155/2185/1956/4254/5296/3845/5600/6777/3265/1399/5781/3480/22916/5663/10254/4916/7529/10787/7314/5879/253260/5595/9296 126 Zaire_ebolavirus R-HSA-162599 Late Phase of HIV Life Cycle 55/1454 139/10654 2.1123149156448362e-14 3.69361733166229e-13 2.1215794547485416e-13 23165/5905/6917/81929/5903/55706/7175/9631/5430/404672/348995/79023/57122/23636/10762/23511/4686/7316/53371/4836/23279/4927/9688/8148/2966/8731/79902/23327/9883/5437/23225/2965/2068/2071/5902/5901/8086/5478/6233/2968/7514/7311/9972/2967/6880/8021/7251/6396/129401/904/1104/55746/22916/8480/7314 55 Zaire_ebolavirus R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 39/1454 79/10654 2.4339844776041256e-14 4.19778966753917e-13 2.411171357049797e-13 9318/6118/6917/27339/5430/404672/7507/2072/8450/7316/9978/64708/5111/2966/10980/6119/5437/1642/2965/10920/2033/2068/10987/2071/6233/2067/2873/2968/7311/2967/8533/6117/2073/5981/7874/50813/7314/51138/8451 39 Zaire_ebolavirus R-HSA-191859 snRNP Assembly 31/1454 53/10654 2.5337530374011355e-14 4.253326765450706e-13 2.443071349746779e-13 23165/81929/5903/6632/55706/7175/6606/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/51808/23225/8086/9972/8021/6396/129401/55746/22916/8480 31 Zaire_ebolavirus R-HSA-194441 Metabolism of non-coding RNA 31/1454 53/10654 2.5337530374011355e-14 4.253326765450706e-13 2.443071349746779e-13 23165/81929/5903/6632/55706/7175/6606/9631/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/51808/23225/8086/9972/8021/6396/129401/55746/22916/8480 31 Zaire_ebolavirus R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 26/1454 39/10654 3.589148938898492e-14 5.945708571148949e-13 3.415159724408953e-13 6118/80010/83990/5888/5892/9156/1763/7486/675/545/472/580/11073/116028/641/6119/3364/5889/84126/1111/672/7156/5890/6117/5884/5810 26 Zaire_ebolavirus R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 31/1454 54/10654 5.178027683537012e-14 8.466411498146882e-13 4.863028050020406e-13 9318/6917/27339/5430/404672/7507/8450/7316/9978/64708/2966/10980/5437/1642/2965/10920/2033/2068/10987/2071/6233/2873/2968/7311/2967/8533/7874/50813/7314/51138/8451 31 Zaire_ebolavirus R-HSA-5685938 HDR through Single Strand Annealing (SSA) 25/1454 37/10654 7.0039739128459e-14 1.1305132251632038e-12 6.493562858468466e-13 6118/80010/25/5893/83990/5888/9156/1763/7486/545/472/580/11073/2072/116028/641/6119/3364/84126/2067/672/7156/6117/5884/5810 25 Zaire_ebolavirus R-HSA-5696394 DNA Damage Recognition in GG-NER 25/1454 38/10654 1.7831089628393688e-13 2.8416888407781837e-12 1.6322396501940657e-12 9318/8450/7316/9978/64708/1643/10980/1642/10920/142/10987/1069/6233/2873/7311/8533/8607/5887/10038/5886/50813/7508/7314/51138/8451 25 Zaire_ebolavirus R-HSA-162909 Host Interactions of HIV factors 51/1454 129/10654 1.9601991563810929e-13 3.084863422354745e-12 1.7719168689918562e-12 23165/5905/8945/1173/3837/81929/5903/8065/55706/7175/9631/4869/6500/348995/79023/57122/23636/10762/23511/7316/9978/53371/292/567/23279/4927/9688/79902/9883/23225/2534/5902/5901/8086/5478/3836/6233/7514/163/7311/9972/3932/8021/6396/129401/904/1104/55746/8480/7314/5879 51 Zaire_ebolavirus R-HSA-176412 Phosphorylation of the APC/C 17/1454 19/10654 2.3719789590060687e-13 3.686816678257581e-12 2.1176732226603888e-12 11065/246184/7321/8697/8881/891/983/51433/51529/7324/64682/29945/10393/51434/5347/29882/996 17 Zaire_ebolavirus R-HSA-933542 TRAF6 mediated NF-kB activation 19/1454 24/10654 7.118619977535455e-13 1.0798003074357997e-11 6.202272573959236e-12 1147/351/7186/4790/57506/4214/7706/8517/5970/4792/4793/3146/23586/64135/7189/6285/84282/3551/4791 19 Zaire_ebolavirus R-HSA-982772 Growth hormone receptor signaling 19/1454 24/10654 7.118619977535455e-13 1.0798003074357997e-11 6.202272573959236e-12 5777/3667/5770/2690/9021/6776/6774/6772/8651/4067/3717/5618/2688/8660/1154/8835/6777/2689/5595 19 Zaire_ebolavirus R-HSA-877312 Regulation of IFNG signaling 14/1454 14/10654 7.364949769286623e-13 1.09087903053316e-11 6.265907729411653e-12 3460/5777/5770/9021/6772/8651/3459/7341/3717/5771/3458/3716/5781/8554 14 Zaire_ebolavirus R-HSA-918233 TRAF3-dependent IRF activation pathway 14/1454 14/10654 7.364949769286623e-13 1.09087903053316e-11 6.265907729411653e-12 3665/80143/29110/57506/7706/23586/1387/2033/64135/3661/84282/7187/9641/3456 14 Zaire_ebolavirus R-HSA-8852135 Protein ubiquitination 37/1454 79/10654 8.929618908122117e-13 1.3072546750378773e-11 7.508749314418474e-12 90268/11065/257218/7319/7321/56852/65264/7320/10477/92912/7336/7326/7323/7316/7317/54926/55236/5111/7415/3093/7322/7347/118424/29089/7328/7324/6233/7327/7311/55284/27338/7334/7874/3105/997/6596/7314 37 Zaire_ebolavirus R-HSA-69473 G2/M DNA damage checkpoint 41/1454 95/10654 1.5312262460449647e-12 2.2158779813455296e-11 1.2727797108685913e-11 6118/80010/83990/9156/1763/7531/7486/7532/10971/51588/7533/2810/11200/545/472/7336/7534/580/11073/891/116028/983/641/9656/6119/3364/7341/165918/84126/1111/7157/8924/672/7158/9025/7156/6117/7334/5884/5810/7529 41 Zaire_ebolavirus R-HSA-162906 HIV Infection 73/1454 233/10654 1.602745861668447e-12 2.2930193634551987e-11 1.3170890035481138e-11 23165/5905/8945/1173/3837/2237/6917/81929/5903/8065/7852/55706/7175/9631/5430/4869/6500/404672/348995/79023/57122/23636/3981/10762/23511/4686/7316/9978/53371/292/567/4836/23279/4927/9688/8148/2966/8731/79902/23327/9883/5437/23225/2965/2534/2068/2071/5902/5901/8086/5478/3836/6233/2968/7514/163/7311/9972/2967/3932/6880/8021/7251/6396/129401/904/1104/2547/55746/22916/8480/7314/5879 73 Zaire_ebolavirus R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 19/1454 25/10654 2.586432727250357e-12 3.6587851725934824e-11 2.1015721864234123e-11 11065/246184/7321/991/8697/8881/7316/51433/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 19 Zaire_ebolavirus R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 40/1454 93/10654 3.2780589973868085e-12 4.535248656824167e-11 2.605004663047701e-11 54106/8454/1147/3665/8945/351/4790/6885/4214/6500/7099/8517/4615/7316/79155/7335/5970/4792/4793/3146/7867/64127/23291/7189/6285/5609/6233/51311/2353/6196/7311/5599/5600/7334/3551/4791/51284/7314/5595/148022 40 Zaire_ebolavirus R-HSA-975155 MyD88 dependent cascade initiated on endosome 40/1454 93/10654 3.2780589973868085e-12 4.535248656824167e-11 2.605004663047701e-11 54106/8454/1147/3665/8945/351/4790/6885/4214/6500/7099/8517/4615/7316/79155/7335/5970/4792/4793/3146/7867/64127/23291/7189/6285/5609/6233/51311/2353/6196/7311/5599/5600/7334/3551/4791/51284/7314/5595/148022 40 Zaire_ebolavirus R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 41/1454 97/10654 3.5049954834762788e-12 4.796510123583299e-11 2.7550708205357015e-11 54106/8454/1147/3665/8945/351/4790/6885/4214/6500/8411/7099/8517/4615/7316/79155/7335/5970/4792/4793/3146/7867/64127/23291/7189/6285/5609/6233/51311/2353/6196/7311/5599/5600/7334/3551/4791/51284/7314/5595/148022 41 Zaire_ebolavirus R-HSA-5633007 Regulation of TP53 Activity 56/1454 160/10654 4.862402908585804e-12 6.582543292375836e-11 3.780951667457213e-11 23774/6118/5170/80010/83990/9156/1763/1029/7486/9219/22974/9212/11200/545/472/580/11073/7316/28996/116028/80196/1457/983/641/8148/6119/5928/3364/57459/1616/54815/2033/84126/1111/3066/3065/7157/1107/8626/5371/6233/2475/672/7311/6880/5300/7156/6117/5600/7874/5884/5810/53615/7314/253260/4193 56 Zaire_ebolavirus R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 40/1454 95/10654 7.462773309128824e-12 9.890138522308621e-11 5.680803615924101e-11 8454/1147/8945/351/4790/6885/4214/6500/10333/7099/8517/4615/7316/79155/7335/5970/4792/7096/4793/8651/3146/7867/64127/23291/114609/7189/6285/5609/6233/2353/6196/7311/5599/5600/7334/7097/3551/4791/7314/5595 40 Zaire_ebolavirus R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 40/1454 95/10654 7.462773309128824e-12 9.890138522308621e-11 5.680803615924101e-11 8454/1147/8945/351/4790/6885/4214/6500/10333/7099/8517/4615/7316/79155/7335/5970/4792/7096/4793/8651/3146/7867/64127/23291/114609/7189/6285/5609/6233/2353/6196/7311/5599/5600/7334/7097/3551/4791/7314/5595 40 Zaire_ebolavirus R-HSA-4420097 VEGFA-VEGFR2 Pathway 41/1454 99/10654 7.78773683751847e-12 1.0213292373370578e-10 5.866420183525427e-11 5295/26999/5170/5590/4893/857/5335/558/5579/1495/1499/5747/4690/10006/10458/5578/3315/5921/1500/9047/10152/6714/7867/3320/2534/9475/998/1398/7410/2475/7409/6093/3685/2185/5296/3845/5600/3265/10787/5879/253260 41 Zaire_ebolavirus R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 16/1454 19/10654 8.686849314985483e-12 1.1274993079965695e-10 6.476251198475341e-11 11065/246184/7321/991/8697/8881/51433/51529/7324/64682/29945/10393/51434/51343/29882/996 16 Zaire_ebolavirus R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 39/1454 92/10654 1.0589977424921581e-11 1.3604879161200275e-10 7.814516101956096e-11 54106/8454/1147/8945/351/4790/6885/4214/6500/7099/8517/4615/7316/79155/7335/5970/4792/4793/3146/7867/64127/23291/7189/6285/5609/6233/51311/2353/6196/7311/5599/5600/7334/3551/4791/51284/7314/5595/148022 39 Zaire_ebolavirus R-HSA-5260271 Diseases of Immune System 18/1454 24/10654 1.4588384876967453e-11 1.8366776560102022e-10 1.0549705695238567e-10 1147/81793/4790/10333/7099/8517/4615/7098/7100/5970/4792/7096/114609/7187/7097/3551/4791/148022 18 Zaire_ebolavirus R-HSA-5602358 Diseases associated with the TLR signaling cascade 18/1454 24/10654 1.4588384876967453e-11 1.8366776560102022e-10 1.0549705695238567e-10 1147/81793/4790/10333/7099/8517/4615/7098/7100/5970/4792/7096/114609/7187/7097/3551/4791/148022 18 Zaire_ebolavirus R-HSA-5689880 Ub-specific processing proteases 68/1454 220/10654 1.875639552346074e-11 2.338049699409611e-10 1.3429540098611284e-10 9960/7186/645836/6885/6314/10474/991/8737/7375/9817/100287364/91833/409/6478/1080/3091/100287513/11274/27005/8517/64750/7316/993/4792/9986/84132/8678/1643/4609/392188/23586/100287144/27430/100287441/3416/9097/7046/6502/9146/408/64135/5728/8724/100287327/7157/9958/4087/63891/7189/57599/6233/377630/100287478/7311/23770/728386/8607/1540/29761/7874/100287404/154/10254/100287178/100287205/7314/4193/100287238 68 Zaire_ebolavirus R-HSA-70171 Glycolysis 33/1454 71/10654 1.989158797944764e-11 2.455246006482802e-10 1.4102704790382382e-10 23165/81929/5903/2597/55706/7175/9631/5315/348995/79023/57122/23636/10762/23511/229/53371/23279/4927/9688/79902/9883/2023/226/23225/8086/5213/9972/8021/6396/129401/2026/55746/8480 33 Zaire_ebolavirus R-HSA-5689896 Ovarian tumor domain proteases 23/1454 38/10654 2.1457891080620444e-11 2.6228626087865184e-10 1.5065478970246546e-10 7321/8737/57506/7706/8517/7316/79155/983/7415/23586/64127/7128/64135/5728/7157/7189/6233/7311/55593/84282/78990/7187/7314 23 Zaire_ebolavirus R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 40/1454 98/10654 2.423719740787383e-11 2.9061553844298243e-10 1.6692686335046939e-10 8454/1147/8945/351/4790/6885/4214/6500/10333/7099/8517/4615/7316/79155/7335/5970/4792/7096/4793/8651/3146/7867/64127/23291/114609/7189/6285/5609/6233/2353/6196/7311/5599/5600/7334/7097/3551/4791/7314/5595 40 Zaire_ebolavirus R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 40/1454 98/10654 2.423719740787383e-11 2.9061553844298243e-10 1.6692686335046939e-10 8454/1147/8945/351/4790/6885/4214/6500/10333/7099/8517/4615/7316/79155/7335/5970/4792/7096/4793/8651/3146/7867/64127/23291/114609/7189/6285/5609/6233/2353/6196/7311/5599/5600/7334/7097/3551/4791/7314/5595 40 Zaire_ebolavirus R-HSA-73893 DNA Damage Bypass 26/1454 48/10654 3.487941528729297e-11 4.1427531930850806e-10 2.3795589178123405e-10 6118/56852/7320/9636/7706/8450/7316/9978/5111/10459/7415/6119/51455/1642/25898/7398/9246/57599/6233/7311/7318/6117/5981/5980/7314/8451 26 Zaire_ebolavirus R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 16/1454 20/10654 3.791541315187253e-11 4.461262164318459e-10 2.5625075096248327e-10 1147/7321/8737/8517/7098/7323/7316/7335/7322/7189/6233/7311/7334/3551/7314/148022 16 Zaire_ebolavirus R-HSA-3899300 SUMOylation of transcription cofactors 25/1454 45/10654 3.970783527045503e-11 4.593876236807741e-10 2.638679799913815e-10 1912/1487/8535/6045/51588/4869/80012/6613/28996/1911/7341/1387/84733/10401/1616/2033/57332/7329/6612/9063/7690/6294/7703/6015/8554 25 Zaire_ebolavirus R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 12/1454 12/10654 4.01371235940311e-11 4.593876236807741e-10 2.638679799913815e-10 3665/29110/7098/7316/3661/6233/10010/7311/7187/9641/7314/148022 12 Zaire_ebolavirus R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 12/1454 12/10654 4.01371235940311e-11 4.593876236807741e-10 2.638679799913815e-10 1147/8737/57506/841/7706/8517/23586/843/64135/84282/8772/3551 12 Zaire_ebolavirus R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 23/1454 39/10654 4.5575758994310484e-11 5.169358610255576e-10 2.969231524807141e-10 10694/26224/22803/10528/898/10517/7203/10576/908/6774/26272/26270/3801/55294/26190/7157/10574/6468/10564/54461/26234/10693/84261 23 Zaire_ebolavirus R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 42/1454 108/10654 4.9673934191127335e-11 5.583882423806189e-10 3.2073301493707216e-10 5295/3605/7124/7291/9655/3592/3566/3561/7184/3593/3684/9021/3553/3091/6657/6778/332/3597/3688/3565/6774/1026/3718/6772/8651/4609/149233/3717/3320/7157/3716/2353/6347/3687/51561/3570/7431/5008/3312/7297/3569/3586 42 Zaire_ebolavirus R-HSA-1257604 PIP3 activates AKT signaling 76/1454 264/10654 5.7880155473889314e-11 6.44877130456873e-10 3.7041142813751235e-10 5295/1912/1147/5170/27161/3643/3667/5468/23186/3815/2146/9112/9219/8535/10273/6045/1027/27327/80012/2064/4615/2100/7316/1457/4233/1026/1911/4734/6714/8503/5928/2261/84733/57459/54815/2534/57332/5728/6009/3630/3066/3065/7157/1107/23028/942/5987/7189/5371/6233/2885/2475/55004/7409/8660/57504/7311/3932/5155/1956/4254/5296/4343/7874/5781/53615/57521/23608/7314/5879/6015/253260/28956/5595/4193/3556 76 Zaire_ebolavirus R-HSA-1433559 Regulation of KIT signaling 14/1454 16/10654 6.746756855288661e-11 7.334234214983822e-10 4.212715944729639e-10 5777/3815/10019/5578/9306/6714/8651/867/4067/2534/2885/7525/3932/4254 14 Zaire_ebolavirus R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 36/1454 85/10654 6.815769683503631e-11 7.334234214983822e-10 4.212715944729639e-10 8454/1147/8945/351/81793/4790/6885/4214/6500/8517/4615/7100/7316/79155/7335/5970/4792/4793/3146/7867/64127/23291/7189/6285/5609/6233/2353/6196/7311/5599/5600/7334/3551/4791/7314/5595 36 Zaire_ebolavirus R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 36/1454 85/10654 6.815769683503631e-11 7.334234214983822e-10 4.212715944729639e-10 8454/1147/8945/351/81793/4790/6885/4214/6500/8517/4615/7100/7316/79155/7335/5970/4792/4793/3146/7867/64127/23291/7189/6285/5609/6233/2353/6196/7311/5599/5600/7334/3551/4791/7314/5595 36 Zaire_ebolavirus R-HSA-975871 MyD88 cascade initiated on plasma membrane 36/1454 85/10654 6.815769683503631e-11 7.334234214983822e-10 4.212715944729639e-10 8454/1147/8945/351/81793/4790/6885/4214/6500/8517/4615/7100/7316/79155/7335/5970/4792/4793/3146/7867/64127/23291/7189/6285/5609/6233/2353/6196/7311/5599/5600/7334/3551/4791/7314/5595 36 Zaire_ebolavirus R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 18/1454 26/10654 1.2886498606250813e-10 1.3749238767177773e-9 7.89743491747931e-10 80010/83990/5888/5892/9156/1763/7486/675/472/580/116028/641/7517/5889/79728/672/7156/5890 18 Zaire_ebolavirus R-HSA-69481 G2/M Checkpoints 55/1454 168/10654 1.4526001305664639e-10 1.5240259439188423e-9 8.753863329060193e-10 6118/80010/5000/83990/9156/1763/7531/7486/7532/8317/10971/51588/7533/2810/4173/11200/545/9133/472/7336/7534/580/11073/7316/891/993/116028/983/641/4171/9656/6119/3364/7341/990/165918/84126/4175/1111/7157/8924/6233/672/7158/7311/9025/7156/6117/7334/5001/5884/5810/4176/7529/7314 55 Zaire_ebolavirus R-HSA-194138 Signaling by VEGF 41/1454 107/10654 1.4526061419401196e-10 1.5240259439188423e-9 8.753863329060193e-10 5295/26999/5170/5590/4893/857/5335/558/5579/1495/1499/5747/4690/10006/10458/5578/3315/5921/1500/9047/10152/6714/7867/3320/2534/9475/998/1398/7410/2475/7409/6093/3685/2185/5296/3845/5600/3265/10787/5879/253260 41 Zaire_ebolavirus R-HSA-8943724 Regulation of PTEN gene transcription 29/1454 61/10654 1.6711057207759213e-10 1.7387785970718057e-9 9.987382602636433e-10 1912/5468/23186/2146/9112/9219/8535/6045/80012/1911/5928/84733/57459/54815/57332/6009/3066/3065/7157/1107/23028/2475/55004/57504/53615/57521/6015/28956/5595 29 Zaire_ebolavirus R-HSA-186763 Downstream signal transduction 19/1454 29/10654 1.6921079805196807e-10 1.7461999569461297e-9 1.003001020377067e-9 5295/4893/5335/4690/5921/6778/6776/6774/6772/6714/2885/1398/5155/5296/3845/6777/3265/1399/5781 19 Zaire_ebolavirus R-HSA-170834 Signaling by TGF-beta Receptor Complex 32/1454 73/10654 2.6656741491749267e-10 2.728523377082303e-9 1.5672384599770429e-9 57154/5590/892/7027/7321/10273/4738/64750/7323/54778/7316/9611/5501/1024/6667/4609/22938/23327/867/7046/142/3065/9958/9040/4087/6233/7514/7311/56288/25937/904/7314 32 Zaire_ebolavirus R-HSA-1059683 Interleukin-6 signaling 11/1454 11/10654 2.96035624678637e-10 3.0057165441161613e-9 1.7264556379815247e-9 9021/6774/6772/867/3717/3716/3570/7297/5781/3569/3572 11 Zaire_ebolavirus R-HSA-6782135 Dual incision in TC-NER 30/1454 66/10654 3.246275116825523e-10 3.2696482976666662e-9 1.878055583376113e-9 6118/6917/27339/5430/404672/7507/2072/8450/7316/9978/5111/2966/6119/5437/1642/2965/2033/2068/2071/6233/2067/2968/7311/2967/6117/2073/5981/7874/7314/8451 30 Zaire_ebolavirus R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 20/1454 33/10654 4.31818641103108e-10 4.280784796447347e-9 2.4588429874665162e-9 1147/351/4790/6885/8517/7316/7335/5970/4792/4793/3146/64127/7189/6285/6233/7311/7334/3551/4791/7314 20 Zaire_ebolavirus R-HSA-5357905 Regulation of TNFR1 signaling 20/1454 33/10654 4.31818641103108e-10 4.280784796447347e-9 2.4588429874665162e-9 7124/1147/90268/7186/8737/55072/7375/841/27005/8517/7316/7128/10616/8567/6233/7311/1540/3551/7185/7314 20 Zaire_ebolavirus R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 29/1454 63/10654 4.4113183047338077e-10 4.338945113796769e-9 2.49224973301984e-9 1147/3665/170506/6737/4790/1499/8737/29110/8517/6778/4615/7098/7316/5970/4792/4793/3428/1387/5437/2033/22954/3661/6233/7311/3551/2547/4791/7314/148022 29 Zaire_ebolavirus R-HSA-70326 Glucose metabolism 36/1454 91/10654 6.812429151142694e-10 6.648719613402055e-9 3.818962730995537e-9 23165/81929/5903/2597/55706/7175/9631/5091/5315/1468/8402/348995/79023/57122/23636/10762/23511/229/53371/23279/4927/9688/79902/9883/2023/226/23225/8086/5213/9972/8021/6396/129401/2026/55746/8480 36 Zaire_ebolavirus R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 15/1454 20/10654 7.850616898551798e-10 7.54498219486772e-9 4.333767624994041e-9 11065/246184/7321/991/8697/8881/51433/51529/7324/64682/29945/10393/51434/29882/996 15 Zaire_ebolavirus R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 15/1454 20/10654 7.850616898551798e-10 7.54498219486772e-9 4.333767624994041e-9 11065/246184/7321/991/8697/8881/51433/51529/7324/64682/29945/10393/51434/29882/996 15 Zaire_ebolavirus R-HSA-6784531 tRNA processing in the nucleus 27/1454 57/10654 7.924454563555611e-10 7.558248708724632e-9 4.341387787211088e-9 23165/81929/5903/55706/7175/9631/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/5901/8086/9972/8021/6396/129401/55746/8480 27 Zaire_ebolavirus R-HSA-5663205 Infectious disease 96/1454 383/10654 8.449342794479539e-10 7.998287652819352e-9 4.594142065538142e-9 3839/23165/5905/8945/1173/3837/3838/2237/6917/81929/5903/8065/7852/402569/55706/7175/9631/1499/3843/5430/4869/821/6500/404672/348995/9636/79023/57122/23636/3981/10762/23511/4686/7316/1500/9978/53371/5611/292/567/4233/4836/6714/23279/4927/9688/8148/2966/8731/79902/6130/3840/23327/9883/867/5437/23225/9146/3320/2965/2534/2068/2071/5902/5901/8086/5478/3836/5609/6233/2885/6844/2968/7514/163/7311/6223/9972/2967/3932/5610/6880/8021/7251/6396/129401/904/1104/2547/55746/22916/10254/6170/8480/7314/5879 96 Zaire_ebolavirus R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 36/1454 92/10654 9.741320074088802e-10 9.084682943168741e-9 5.218157419804294e-9 6118/80010/83990/9156/1763/7486/22974/9212/11200/545/472/580/11073/7316/28996/116028/1457/641/8148/6119/3364/84126/1111/7157/6233/672/7311/6880/5300/7156/6117/5600/5884/5810/7314/4193 36 Zaire_ebolavirus R-HSA-877300 Interferon gamma signaling 36/1454 92/10654 9.741320074088802e-10 9.084682943168741e-9 5.218157419804294e-9 3665/3460/5777/6737/10379/960/5770/3107/2633/9021/85363/9830/8638/7706/4684/567/6672/6772/8651/3659/3459/4939/7341/3717/5771/10612/3458/3661/5371/3716/81603/4940/4938/5781/3105/8554 36 Zaire_ebolavirus R-HSA-9006925 Intracellular signaling by second messengers 81/1454 305/10654 1.026069002527222e-9 9.498682898395385e-9 5.455955145017038e-9 5295/1912/1147/5170/27161/3643/3838/3667/5335/5468/23186/3815/2146/9112/9219/8535/10273/6045/5578/1027/5582/27327/80012/2064/4615/2100/7316/1457/4233/1026/1911/4734/6714/8503/5928/2261/84733/57459/5576/54815/2534/57332/5728/6009/3630/3066/3065/7157/1107/23028/942/5987/7189/5371/6233/2885/2475/55004/7409/8660/57504/7311/3932/5155/1956/4254/5296/4343/7874/5781/53615/57521/23608/7314/5879/6015/253260/28956/5595/4193/3556 81 Zaire_ebolavirus R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 26/1454 55/10654 1.7256656300077785e-9 1.585848925678681e-8 9.10896878843906e-9 1147/834/9447/351/4790/6885/10910/29108/841/8517/7316/7335/5970/64127/7128/83737/7189/6233/7311/114548/5600/7334/1540/3551/4791/7314 26 Zaire_ebolavirus R-HSA-5693607 Processing of DNA double-strand break ends 37/1454 98/10654 1.859268250145226e-9 1.696245454299159e-8 9.74307618497155e-9 6118/80010/83990/9156/1763/7486/51588/545/472/6613/7336/580/11073/7316/116028/641/9656/6119/3364/7341/165918/84126/1111/7329/8924/6233/672/7158/7311/6047/9025/7156/6117/7334/5884/5810/7314 37 Zaire_ebolavirus R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 13/1454 16/10654 2.0356857984448776e-9 1.8438333958576264e-8 1.0590807599633705e-8 8454/1147/8945/4790/6500/8517/7316/79155/23291/6233/7311/3551/7314 13 Zaire_ebolavirus R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 31/1454 75/10654 2.946201939389619e-9 2.64947731549395e-8 1.5218351371132843e-8 23165/81929/5903/55706/7175/9631/84271/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10482/8086/9972/8021/6396/129401/79228/55746/22916/8480 31 Zaire_ebolavirus R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 18/1454 30/10654 4.1346845550667234e-9 3.691892095623407e-8 2.120588495207793e-8 7124/1147/7186/6885/8737/55072/7375/27005/8517/7316/7128/10616/6233/7311/1540/3551/7185/7314 18 Zaire_ebolavirus R-HSA-75893 TNF signaling 22/1454 43/10654 4.767275509786239e-9 4.226760469592166e-8 2.4278119163996632e-8 7124/1147/90268/7186/6885/8737/55072/7375/841/27005/8517/7316/7128/10616/8567/6233/7311/8772/1540/3551/7185/7314 22 Zaire_ebolavirus R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 38/1454 106/10654 6.131906372751729e-9 5.398650435870229e-8 3.1009346176521436e-8 9318/1173/10618/4738/409/1080/29978/7316/64708/22905/10980/7037/867/9341/9146/10920/3482/408/10987/115548/29979/6233/2885/2873/6844/163/7311/3575/6845/1956/8533/8673/154/10254/50813/7314/50618/51138 38 Zaire_ebolavirus R-HSA-1980143 Signaling by NOTCH1 30/1454 73/10654 6.2310744061324766e-009 5.447862970361658e-8 3.1292018399217916e-8 8454/142678/892/3280/6500/409/3091/10013/23385/7316/9978/9611/8650/9759/102/1024/4609/22938/1387/2033/408/55294/3066/3065/83737/6233/7311/4851/5663/7314 30 Zaire_ebolavirus R-HSA-912631 Regulation of signaling by CBL 15/1454 22/10654 6.589748237518721e-9 5.7217193317490144e-8 3.286502387786106e-8 5295/7316/8503/867/4067/2534/6233/2885/7525/1398/7409/7311/5296/1399/7314 15 Zaire_ebolavirus R-HSA-937041 IKK complex recruitment mediated by RIP1 16/1454 25/10654 8.112063756097694e-9 6.99526593762123e-8 4.018015717692224e-8 1147/7321/8737/7099/8517/7323/7316/7335/7322/7189/6233/7311/7334/3551/7314/148022 16 Zaire_ebolavirus R-HSA-451927 Interleukin-2 family signaling 22/1454 44/10654 8.312051226787639e-9 7.118960880629684e-8 4.089064942930975e-8 5295/5777/1437/3561/6775/1439/6776/3560/6774/3718/6772/8503/3558/3717/3563/2885/3716/3932/2185/5296/6777/3559 22 Zaire_ebolavirus R-HSA-1170546 Prolactin receptor signaling 12/1454 15/10654 1.2235154409060193e-8 1.0338294900004553e-7 5.938220472641719e-8 8454/8945/2690/6500/6776/9978/3717/5618/2688/6777/2689/5781 12 Zaire_ebolavirus R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 12/1454 15/10654 1.2235154409060193e-8 1.0338294900004553e-7 5.938220472641719e-8 54106/3665/4615/7316/7335/7189/6233/51311/7311/7334/51284/7314 12 Zaire_ebolavirus R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 11/1454 13/10654 1.7710118587605436e-8 1.4864692867863493e-7 8.538141382235041e-8 7531/7532/10971/7533/2810/11200/7534/891/983/1111/7529 11 Zaire_ebolavirus R-HSA-2586552 Signaling by Leptin 10/1454 11/10654 2.104313065063298e-8 1.7429803611280868e-7 1.0011517144726356e-7 3667/3953/9021/3952/6776/6774/3717/8660/6777/5781 10 Zaire_ebolavirus R-HSA-4755510 SUMOylation of immune response proteins 10/1454 11/10654 2.104313065063298e-8 1.7429803611280868e-7 1.0011517144726356e-7 51588/8517/5970/4792/7341/10401/7329/6612/9641/4791 10 Zaire_ebolavirus R-HSA-2559583 Cellular Senescence 56/1454 195/10654 2.187470329931261e-8 1.8000164348911486e-7 1.0339127049623505e-7 1912/11065/4790/246184/1029/7027/7321/2146/8535/6045/8697/1027/27327/80012/898/472/8881/7316/6774/5970/1026/1911/6667/7867/51433/5928/84733/57332/7157/51529/23135/7324/4001/64682/29945/10393/5609/6233/51434/2353/51343/6196/7311/4343/29882/5599/5600/4217/3456/3569/7314/996/6015/5595/4193/23043 56 Zaire_ebolavirus R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 13/1454 18/10654 2.3821455824204058e-8 1.9474813560177215e-7 1.1186151846362398e-7 3665/29110/7099/7316/3661/6233/10010/7311/7187/9641/5781/7314/148022 13 Zaire_ebolavirus R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs 14/1454 21/10654 3.333615413616114e-8 2.70775600370496e-7 1.555309873788978e-7 1147/4790/8737/29110/8517/4615/7098/5970/4792/4793/3661/3551/4791/148022 14 Zaire_ebolavirus R-HSA-2644602 Signaling by NOTCH1 PEST Domain Mutants in Cancer 25/1454 58/10654 3.6451005466304096e-8 2.868238492629804e-7 1.6474895233783493e-7 8454/142678/892/3280/6500/10013/23385/7316/9978/9611/9759/102/1024/4609/22938/1387/2033/55294/3066/3065/6233/7311/4851/5663/7314 25 Zaire_ebolavirus R-HSA-2644603 Signaling by NOTCH1 in Cancer 25/1454 58/10654 3.6451005466304096e-8 2.868238492629804e-7 1.6474895233783493e-7 8454/142678/892/3280/6500/10013/23385/7316/9978/9611/9759/102/1024/4609/22938/1387/2033/55294/3066/3065/6233/7311/4851/5663/7314 25 Zaire_ebolavirus R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 25/1454 58/10654 3.6451005466304096e-8 2.868238492629804e-7 1.6474895233783493e-7 8454/142678/892/3280/6500/10013/23385/7316/9978/9611/9759/102/1024/4609/22938/1387/2033/55294/3066/3065/6233/7311/4851/5663/7314 25 Zaire_ebolavirus R-HSA-2894858 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 25/1454 58/10654 3.6451005466304096e-8 2.868238492629804e-7 1.6474895233783493e-7 8454/142678/892/3280/6500/10013/23385/7316/9978/9611/9759/102/1024/4609/22938/1387/2033/55294/3066/3065/6233/7311/4851/5663/7314 25 Zaire_ebolavirus R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 25/1454 58/10654 3.6451005466304096e-8 2.868238492629804e-7 1.6474895233783493e-7 8454/142678/892/3280/6500/10013/23385/7316/9978/9611/9759/102/1024/4609/22938/1387/2033/55294/3066/3065/6233/7311/4851/5663/7314 25 Zaire_ebolavirus R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 17/1454 30/10654 3.7175869995615466e-8 2.907106852452166e-7 1.6698151478906716e-7 6118/56852/7320/8450/7316/9978/5111/6119/1642/7398/57599/6233/7311/6117/5981/7314/8451 17 Zaire_ebolavirus R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 22/1454 47/10654 3.8835328859973396e-8 3.0181283354757105e-7 1.7335848555426717e-7 8454/892/3280/6500/3091/10013/7316/9978/9611/9759/1024/4609/22938/1387/2033/55294/3066/3065/6233/7311/4851/7314 22 Zaire_ebolavirus R-HSA-6807070 PTEN Regulation 44/1454 140/10654 3.987487397810514e-8 3.079905910333397e-7 1.7690693201781228e-7 1912/27161/5468/23186/2146/9112/9219/8535/10273/6045/27327/80012/7316/1457/1911/4734/5928/84733/57459/54815/57332/5728/6009/3066/3065/7157/1107/23028/5987/5371/6233/2475/55004/57504/7311/4343/7874/53615/57521/23608/7314/6015/28956/5595 44 Zaire_ebolavirus R-HSA-110312 Translesion synthesis by REV1 12/1454 16/10654 4.2833560240905974e-8 3.2882592892256474e-7 1.8887455638961745e-7 6118/7316/5111/10459/6119/51455/6233/7311/6117/5981/5980/7314 12 Zaire_ebolavirus R-HSA-68886 M Phase 93/1454 395/10654 4.356154119755876e-8 3.323877598044029e-7 1.9092043893284127e-7 10844/4000/23165/5905/81929/5903/11065/55706/7175/55143/5579/9631/246184/9735/7531/7321/991/203068/7532/8697/5578/9212/3619/140609/5861/10783/23244/348995/79023/9133/10381/57122/23636/332/23047/10762/8881/23141/23511/7316/891/5501/53371/26003/1457/983/23279/4927/9688/10121/51433/79902/9883/1062/7846/23225/7283/7444/347733/3320/22919/10376/51529/1069/8086/7324/2010/4001/64682/29945/10393/23592/6233/51434/7514/7311/9972/10383/5347/8021/29882/6396/129401/84930/27229/55746/7112/7280/55755/8480/7314/996/5595 93 Zaire_ebolavirus R-HSA-168254 Influenza Infection 47/1454 155/10654 4.804678328096667e-8 3.6440301295624723e-7 2.0930970268880218e-7 3839/23165/3837/3838/81929/5903/402569/55706/7175/9631/3843/5430/821/348995/9636/79023/57122/23636/10762/23511/53371/5611/23279/4927/9688/79902/6130/3840/9883/5437/23225/3320/5901/8086/3836/6233/7514/7311/6223/9972/5610/8021/6396/129401/55746/6170/8480 47 Zaire_ebolavirus R-HSA-73887 Death Receptor Signalling 44/1454 141/10654 5.044101506519292e-8 3.8027088603040646e-7 2.1842406145469605e-7 7124/1147/90268/7186/4790/6885/10018/7531/8737/55072/7375/8878/1894/23385/841/27005/8517/4615/7316/5970/4792/7128/843/836/10616/396/8837/3066/3065/8567/7189/6233/7410/7409/7311/8772/5599/1540/3551/7185/8743/5663/7314/5879 44 Zaire_ebolavirus R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 21/1454 44/10654 5.1744614937703954e-8 3.877766083724362e-7 2.227352785852294e-7 892/7027/7321/64750/7323/54778/7316/9611/1024/6667/4609/22938/23327/142/3065/4087/6233/7311/25937/904/7314 21 Zaire_ebolavirus R-HSA-69242 S Phase 48/1454 161/10654 6.22977171680492e-8 4.640995616246979e-7 2.6657447333821116e-7 8454/6118/2237/5000/11065/246184/1763/7027/7321/8697/1027/6500/898/23244/4173/23047/8881/7316/5422/9978/5753/993/1026/5111/4171/4609/51433/6119/5928/6502/990/4175/51529/7324/64682/29945/10393/6233/51434/51343/7311/6117/29882/5001/5981/4176/7314/996 48 Zaire_ebolavirus R-HSA-68875 Mitotic Prophase 44/1454 142/10654 6.360439209549975e-8 4.7104664498961287e-7 2.7056481343410724e-7 4000/23165/81929/5903/55706/7175/5579/9631/5578/140609/5861/10783/348995/79023/9133/57122/23636/10762/23511/891/53371/26003/983/23279/4927/9688/79902/9883/23225/7444/8086/2010/4001/23592/9972/5347/8021/6396/129401/84930/55746/7112/8480/5595 44 Zaire_ebolavirus R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 13/1454 19/10654 6.598102764778219e-8 4.829657779567313e-7 2.774110525950206e-7 5295/4893/5335/7316/867/3320/6233/2885/7311/1956/3845/3265/7314 13 Zaire_ebolavirus R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 13/1454 19/10654 6.598102764778219e-8 4.829657779567313e-7 2.774110525950206e-7 5295/4893/5335/7316/867/3320/6233/2885/7311/1956/3845/3265/7314 13 Zaire_ebolavirus R-HSA-69239 Synthesis of DNA 39/1454 119/10654 6.660952000753709e-8 4.847478941588971e-7 2.784346835727288e-7 8454/6118/2237/5000/11065/246184/1763/7321/8697/6500/898/4173/8881/7316/5422/9978/5111/4171/51433/6119/6502/990/4175/51529/7324/64682/29945/10393/6233/51434/51343/7311/6117/29882/5001/5981/4176/7314/996 39 Zaire_ebolavirus R-HSA-72202 Transport of Mature Transcript to Cytoplasm 31/1454 84/10654 7.047096303808344e-8 5.099019681893509e-7 2.92882949831599e-7 23165/81929/5903/55706/7175/9631/84271/348995/79023/57122/23636/10762/23511/4686/53371/23279/4927/9688/79902/9883/23225/10482/8086/9972/8021/6396/129401/79228/55746/22916/8480 31 Zaire_ebolavirus R-HSA-9027284 Erythropoietin activates RAS 11/1454 14/10654 7.239434861465245e-8 5.208256280334138e-7 2.991573984858119e-7 4893/4067/3717/2057/2885/2056/7409/8660/3845/3265/1399 11 Zaire_ebolavirus R-HSA-5663202 Diseases of signal transduction 89/1454 377/10654 7.515257239700663e-8 5.375970945899508e-7 3.087907729470308e-7 5295/8454/4000/1147/5170/7276/4893/3667/5335/1487/142678/1499/10018/892/3815/5430/3280/1027/6500/409/5908/10533/10013/23385/2064/6776/2100/4686/7316/9978/9611/8546/6774/4233/9759/102/1026/1024/6772/6714/4609/7415/22938/8503/2261/867/1387/5437/7046/3717/3320/2534/2033/408/55294/5728/1445/3066/3065/4087/942/6233/2885/2475/7409/56829/8660/7311/3932/5155/1956/4254/5296/4140/3845/6777/3265/369/5781/4851/22916/5663/7529/7314/1523/5879/253260/5595/4193 89 Zaire_ebolavirus R-HSA-9006335 Signaling by Erythropoietin 15/1454 25/10654 8.424215776894298e-8 5.992139922660973e-7 3.441829461032639e-7 5295/4893/5335/6776/4067/3717/2057/2885/2056/7409/8660/3845/6777/3265/1399 15 Zaire_ebolavirus R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 42/1454 134/10654 8.810150330259029e-8 6.231449025728156e-7 3.579286384913041e-7 5295/8454/1147/5170/8945/4893/4773/5335/4790/6885/7321/4214/6500/8517/7316/7335/5970/4792/7322/4067/23291/2534/7189/5609/6233/2885/7410/7006/7409/3702/2353/7311/5296/3845/5599/7334/3265/3551/997/7314/5879/5595 42 Zaire_ebolavirus R-HSA-210990 PECAM1 interactions 10/1454 12/10654 1.1070418822075116e-7 7.700363147509708e-7 4.4230169995729017e-7 5777/5335/5175/6714/4067/2534/7525/3685/3932/5781 10 Zaire_ebolavirus R-HSA-8984722 Interleukin-35 Signalling 10/1454 12/10654 1.1070418822075116e-7 7.700363147509708e-7 4.4230169995729017e-7 3592/6775/3595/821/6774/6772/3717/3716/7297/3572 10 Zaire_ebolavirus R-HSA-9020558 Interleukin-2 signaling 10/1454 12/10654 1.1070418822075116e-7 7.700363147509708e-7 4.4230169995729017e-7 3561/6776/3560/3718/3558/3716/3932/2185/6777/3559 10 Zaire_ebolavirus R-HSA-447115 Interleukin-12 family signaling 24/1454 57/10654 1.1755660313427496e-7 8.132074909123746e-7 4.670988221703117e-7 3592/6627/9049/3593/6775/3595/821/5908/6774/6772/149233/3717/3458/998/5478/4001/3716/3594/4507/6845/51561/7297/3586/3572 24 Zaire_ebolavirus R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 26/1454 65/10654 1.225040006307597e-7 8.428007475088878e-7 4.840969136228468e-7 6118/6917/27339/5430/404672/8450/7316/9978/5111/2966/6119/5437/1642/2965/2033/2068/2071/6233/2968/7311/2967/6117/5981/7874/7314/8451 26 Zaire_ebolavirus R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 12/1454 17/10654 1.2747591858786023e-7 8.628611908715916e-7 4.956194457830219e-7 1147/4790/8737/8517/4615/7098/5970/4792/4793/3551/4791/148022 12 Zaire_ebolavirus R-HSA-5655862 Translesion synthesis by POLK 12/1454 17/10654 1.2747591858786023e-7 8.628611908715916e-7 4.956194457830219e-7 6118/7316/5111/10459/6119/51455/6233/7311/6117/5981/5980/7314 12 Zaire_ebolavirus R-HSA-5656121 Translesion synthesis by POLI 12/1454 17/10654 1.2747591858786023e-7 8.628611908715916e-7 4.956194457830219e-7 6118/7316/5111/10459/6119/51455/6233/7311/6117/5981/5980/7314 12 Zaire_ebolavirus R-HSA-110056 MAPK3 (ERK1) activation 9/1454 10/10654 1.411139247014371e-7 9.450129319101559e-7 5.42806642048641e-7 983/3717/3716/3570/7297/5781/3569/3572/5595 9 Zaire_ebolavirus R-HSA-3215018 Processing and activation of SUMO 9/1454 10/10654 1.411139247014371e-7 9.450129319101559e-7 5.42806642048641e-7 10054/29843/6613/7341/10055/59343/7329/6612/205564 9 Zaire_ebolavirus R-HSA-69306 DNA Replication 40/1454 127/10654 1.5367220261495727e-7 1.0236682703292656e-6 5.879855371566453e-7 8454/6118/2237/5000/11065/246184/1763/7321/8317/8697/6500/898/4173/8881/7316/5422/9978/5111/4171/51433/6119/6502/990/4175/51529/7324/64682/29945/10393/6233/51434/51343/7311/6117/29882/5001/5981/4176/7314/996 40 Zaire_ebolavirus R-HSA-8856828 Clathrin-mediated endocytosis 44/1454 146/10654 1.5593894980832553e-7 1.0333007253088518e-6 5.935183297413831e-7 9318/1173/5868/10618/4738/409/1080/29978/7316/64708/22905/26052/10980/7037/867/9341/9146/10920/3482/408/10987/115548/5878/29979/6233/2885/2873/10096/6844/163/7311/3575/6845/1956/8533/3312/8673/154/10254/50813/7314/50618/51138/11252 44 Zaire_ebolavirus R-HSA-3232118 SUMOylation of transcription factors 13/1454 20/10654 1.6490892023390046e-7 1.087017437562726e-6 6.243727098412214e-7 1029/9112/51588/6613/7341/10401/7157/7329/7158/6612/9063/4193/8554 13 Zaire_ebolavirus R-HSA-8848021 Signaling by PTK6 23/1454 54/10654 1.6707394575835714e-7 1.0898761539366407e-6 6.260147299481392e-7 120892/4893/5770/9021/1027/898/3091/2064/5921/7316/5753/6774/867/2908/6233/1398/7311/2034/1956/3845/3265/7314/5879 23 Zaire_ebolavirus R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases 23/1454 54/10654 1.6707394575835714e-7 1.0898761539366407e-6 6.260147299481392e-7 120892/4893/5770/9021/1027/898/3091/2064/5921/7316/5753/6774/867/2908/6233/1398/7311/2034/1956/3845/3265/7314/5879 23 Zaire_ebolavirus R-HSA-168638 NOD1/2 Signaling Pathway 18/1454 36/10654 1.9172676360348288e-7 1.244247398849407e-6 7.146841377948601e-7 1147/834/6885/841/8517/7316/7335/64127/7128/83737/7189/6233/7311/5600/7334/1540/3551/7314 18 Zaire_ebolavirus R-HSA-9006936 Signaling by TGF-beta family members 34/1454 102/10654 2.9086859498973983e-7 1.8779669799593972e-6 1.078686773322274e-6 57154/5590/892/7027/9765/7321/10273/4738/64750/7323/54778/7316/9611/5501/1024/6667/4609/22938/23327/867/7046/142/3065/9958/9040/4087/6233/7514/7311/56288/25937/10589/904/7314 34 Zaire_ebolavirus R-HSA-176187 Activation of ATR in response to replication stress 18/1454 37/10654 3.259254966787628e-7 2.09357245060491e-6 1.2025285511187433e-6 6118/5000/8317/4173/545/993/4171/6119/3364/990/84126/4175/1111/6117/5001/5884/5810/4176 18 Zaire_ebolavirus R-HSA-912526 Interleukin receptor SHC signaling 15/1454 27/10654 3.421472864541899e-7 2.1866164144458125e-6 1.2559721388940874e-6 5295/5777/1437/3561/1439/3560/3718/8503/3558/3717/3563/2885/3716/5296/3559 15 Zaire_ebolavirus R-HSA-450294 MAP kinase activation 25/1454 64/10654 3.67103903080895e-7 2.3342616867618527e-6 1.340778210614433e-6 8454/1147/8945/4790/6885/6500/8517/7316/79155/7335/7867/64127/23291/7189/5609/6233/2353/6196/7311/5599/5600/7334/3551/7314/5595 25 Zaire_ebolavirus R-HSA-209560 NF-kB is activated and signals survival 10/1454 13/10654 4.206844203312377e-7 2.6615160060152175e-6 1.528750049021742e-6 4790/8878/7316/5970/4792/7189/6233/7311/3551/7314 10 Zaire_ebolavirus R-HSA-69052 Switching of origins to a post-replicative state 31/1454 90/10654 4.2503727032471103e-7 2.675609616694056e-6 1.5368452879635602e-6 8454/5000/11065/246184/7321/8697/6500/898/4173/8881/7316/9978/4171/51433/6502/990/4175/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/5001/4176/7314/996 31 Zaire_ebolavirus R-HSA-68882 Mitotic Anaphase 54/1454 201/10654 4.3021019632451077e-7 2.694699687425667e-6 1.5478104471062524e-6 4000/5905/81929/5903/11065/55143/246184/9735/7321/991/8697/9212/3619/23244/348995/79023/10381/57122/332/23047/8881/23141/7316/5501/23279/51433/79902/1062/7846/7444/347733/22919/10376/51529/7324/2010/4001/64682/29945/10393/23592/6233/51434/7514/7311/10383/5347/29882/6396/55746/7112/7280/7314/996 54 Zaire_ebolavirus R-HSA-390466 Chaperonin-mediated protein folding 32/1454 95/10654 4.947740306559128e-7 3.083764874236605e-6 1.7712858731662952e-6 10694/26224/22803/10528/5203/898/10381/10517/7203/10576/908/6774/1457/26272/26270/7846/347733/3801/10376/55294/26190/7157/10574/6468/10564/10383/54461/26234/10693/7280/84261/5201 32 Zaire_ebolavirus R-HSA-2555396 Mitotic Metaphase and Anaphase 54/1454 202/10654 5.109013768994176e-7 3.16859523899688e-6 1.8200116459937767e-6 4000/5905/81929/5903/11065/55143/246184/9735/7321/991/8697/9212/3619/23244/348995/79023/10381/57122/332/23047/8881/23141/7316/5501/23279/51433/79902/1062/7846/7444/347733/22919/10376/51529/7324/2010/4001/64682/29945/10393/23592/6233/51434/7514/7311/10383/5347/29882/6396/55746/7112/7280/7314/996 54 Zaire_ebolavirus R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 25/1454 65/10654 5.199788421122301e-7 3.2090851089181258e-6 1.8432686508312798e-6 2176/6917/4436/5892/5430/404672/4292/545/472/1643/2966/9656/5437/2177/2965/2068/1111/2071/7157/55215/2968/672/2353/2967/904 25 Zaire_ebolavirus R-HSA-193639 p75NTR signals via NF-kB 11/1454 16/10654 6.66828992046101e-7 4.095305858468493e-6 2.3523056099392624e-6 4790/8878/4615/7316/5970/4792/7189/6233/7311/3551/7314 11 Zaire_ebolavirus R-HSA-1227986 Signaling by ERBB2 21/1454 50/10654 7.622630088810666e-7 4.658685088258558e-6 2.675905401641762e-6 5295/4893/8065/5335/10273/5578/10193/2064/7316/5753/6714/3320/2534/6233/2885/7525/7311/1956/3845/3265/7314 21 Zaire_ebolavirus R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 18/1454 39/10654 8.765480954015018e-7 5.3312756140603426e-6 3.062235146406467e-6 6118/9636/7706/7316/5111/10459/7415/6119/51455/25898/9246/6233/7311/7318/6117/5981/5980/7314 18 Zaire_ebolavirus R-HSA-2173789 TGF-beta receptor signaling activates SMADs 16/1454 32/10654 9.259407456806094e-7 5.604612494287919e-6 3.2192373091223617e-6 57154/10273/4738/64750/7316/5501/23327/867/7046/9958/9040/4087/6233/7514/7311/7314 16 Zaire_ebolavirus R-HSA-69618 Mitotic Spindle Checkpoint 35/1454 112/10654 1.1157120773593017e-6 6.720964140647659e-6 3.860459315768523e-6 5905/81929/5903/11065/55143/246184/9735/7321/991/8697/9212/3619/348995/79023/57122/332/8881/5501/23279/51433/79902/1062/22919/51529/7324/64682/29945/10393/51434/7514/5347/29882/6396/55746/996 35 Zaire_ebolavirus R-HSA-1266695 Interleukin-7 signaling 17/1454 36/10654 1.183321856013577e-6 7.094296270100445e-6 4.074897819956528e-6 5295/3667/6597/3561/6776/6774/3718/8651/8503/3716/8660/1154/3575/5896/5296/8835/6777 17 Zaire_ebolavirus R-HSA-448424 Interleukin-17 signaling 26/1454 72/10654 1.287576649332065e-6 7.682744082981372e-6 4.41289677271703e-6 8454/3605/1147/8945/4790/6885/6500/8517/7316/79155/7335/7867/64127/23291/7189/5609/6233/2353/6196/7311/5599/5600/7334/3551/7314/5595 26 Zaire_ebolavirus R-HSA-5619102 SLC transporter disorders 32/1454 99/10654 1.398453942125224e-6 8.304969401583288e-6 4.770297210725068e-6 23165/81929/5903/55706/7175/9631/5002/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/23225/682/8086/6520/6575/9972/8021/6396/129401/213/55746/6566/8480 32 Zaire_ebolavirus R-HSA-389356 CD28 co-stimulation 16/1454 33/10654 1.5704939389470608e-6 9.282872625043895e-6 5.331995730450362e-6 5295/5170/6714/8503/4067/2534/998/942/2885/7525/2475/7409/3932/5296/5879/253260 16 Zaire_ebolavirus R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 13/1454 23/10654 1.6301877898511033e-6 9.590684240292238e-6 5.508799860441259e-6 7321/64750/7323/54778/7316/9611/23327/142/3065/4087/6233/7311/7314 13 Zaire_ebolavirus R-HSA-4655427 SUMOylation of DNA methylation proteins 11/1454 17/10654 1.6556429600528759e-6 9.683411649353126e-6 5.5620616220940575e-6 1912/8535/6045/80012/1911/7341/84733/57332/7329/7703/6015 11 Zaire_ebolavirus R-HSA-109581 Apoptosis 48/1454 178/10654 1.6613319430184872e-6 9.683411649353126e-6 5.5620616220940575e-6 4000/3837/1676/7186/219699/1499/10018/7531/1029/5747/7027/8737/7532/10971/7533/2810/118/1829/841/7099/7534/100506658/7316/6774/5339/4836/3146/836/8837/3002/7157/8626/4001/3836/6233/6093/7311/1677/8772/5599/7431/26060/8743/6304/7529/7314/5595/148022 48 Zaire_ebolavirus R-HSA-8876384 Listeria monocytogenes entry into host cells 12/1454 20/10654 1.741615086225902e-6 1.0104577850499589e-5 5.803975572336622e-6 1499/7316/1500/4233/6714/867/9146/6233/2885/7311/10254/7314 12 Zaire_ebolavirus R-HSA-168255 Influenza Life Cycle 41/1454 144/10654 2.1195071056801277e-6 1.224063966078569e-5 7.030909616621186e-6 23165/3837/81929/5903/55706/7175/9631/3843/5430/821/348995/79023/57122/23636/10762/23511/53371/5611/23279/4927/9688/79902/6130/9883/5437/23225/3320/5901/8086/3836/6233/7514/7311/6223/9972/8021/6396/129401/55746/6170/8480 41 Zaire_ebolavirus R-HSA-391251 Protein folding 32/1454 101/10654 2.2840241686352854e-6 1.3070847401417383e-5 7.507773224174359e-6 10694/26224/22803/10528/5203/898/10381/10517/7203/10576/908/6774/1457/26272/26270/7846/347733/3801/10376/55294/26190/7157/10574/6468/10564/10383/54461/26234/10693/7280/84261/5201 32 Zaire_ebolavirus R-HSA-5607764 CLEC7A (Dectin-1) signaling 32/1454 101/10654 2.2840241686352854e-6 1.3070847401417383e-5 7.507773224174359e-6 8454/1147/5170/8945/4773/4790/6885/7321/3553/9039/6500/29108/841/8517/7316/64581/7335/5970/4792/6714/7322/23291/9040/7189/6233/7311/5971/7334/3551/997/4791/7314 32 Zaire_ebolavirus R-HSA-5689877 Josephin domain DUBs 9/1454 12/10654 2.3936174270579807e-6 1.3636037740570126e-5 7.832413300256407e-6 4287/7316/7415/9929/6233/7311/5887/5886/7314 9 Zaire_ebolavirus R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 60/1454 244/10654 2.5434318842825885e-6 1.4424237577980985e-5 8.28514795875836e-6 23165/23451/81929/5903/6632/6627/55706/7175/9631/27339/84271/5430/51639/3178/23450/348995/79023/57122/23636/3183/10762/5093/23511/10594/4686/53371/9343/3190/23279/4927/9688/79902/22938/988/9883/5437/23225/10482/10421/8086/2521/3191/10285/27316/10286/9972/5094/8021/3192/6396/129401/79228/3312/5356/55746/22916/56259/26121/8480/1994 60 Zaire_ebolavirus R-HSA-446652 Interleukin-1 family signaling 40/1454 140/10654 2.5560945686527598e-6 1.4431045120779483e-5 8.289058148050253e-6 8454/1147/834/5777/8945/351/4790/6885/5783/29110/3553/8878/6500/8517/4615/7316/3565/9978/79155/6774/7335/5970/4792/4793/3146/64127/23291/5771/7189/6285/6233/84639/7311/5599/7334/3551/5781/4791/7314/3556 40 Zaire_ebolavirus R-HSA-6806834 Signaling by MET 27/1454 79/10654 2.7757248978308427e-6 1.5537851979292736e-5 8.924797717297862e-6 5295/3675/4893/5770/5747/5908/3688/7316/6774/4233/6714/3673/867/9146/5771/6233/2885/1398/5867/7311/3845/3265/1399/5781/10254/7314/5879 27 Zaire_ebolavirus R-HSA-5357801 Programmed Cell Death 48/1454 181/10654 2.7768202504693132e-6 1.5537851979292736e-5 8.924797717297862e-6 4000/3837/1676/7186/219699/1499/10018/7531/1029/5747/7027/8737/7532/10971/7533/2810/118/1829/841/7099/7534/100506658/7316/6774/5339/4836/3146/836/8837/3002/7157/8626/4001/3836/6233/6093/7311/1677/8772/5599/7431/26060/8743/6304/7529/7314/5595/148022 48 Zaire_ebolavirus R-HSA-937039 IRAK1 recruits IKK complex 10/1454 15/10654 3.3985645335080583e-6 1.8849307258531476e-5 1.0826866842198171e-5 1147/8517/7316/7335/7189/6233/7311/7334/3551/7314 10 Zaire_ebolavirus R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 10/1454 15/10654 3.3985645335080583e-6 1.8849307258531476e-5 1.0826866842198171e-5 1147/8517/7316/7335/7189/6233/7311/7334/3551/7314 10 Zaire_ebolavirus R-HSA-9020958 Interleukin-21 signaling 8/1454 10/10654 4.118396700251542e-6 2.274149756849426e-5 1.3062504769495888e-5 3561/6775/6776/6774/3718/6772/3716/6777 8 Zaire_ebolavirus R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 28/1454 86/10654 5.372702402412872e-6 2.9409705759294806e-5 1.6892661558158546e-5 8454/8945/11065/246184/7321/991/8697/9212/6500/8881/7316/891/983/51433/6502/51529/7324/64682/29945/10393/6233/51434/51343/7311/5347/29882/7314/996 28 Zaire_ebolavirus R-HSA-453276 Regulation of mitotic cell cycle 28/1454 86/10654 5.372702402412872e-6 2.9409705759294806e-5 1.6892661558158546e-5 8454/8945/11065/246184/7321/991/8697/9212/6500/8881/7316/891/983/51433/6502/51529/7324/64682/29945/10393/6233/51434/51343/7311/5347/29882/7314/996 28 Zaire_ebolavirus R-HSA-1643713 Signaling by EGFR in Cancer 13/1454 25/10654 5.675778122455106e-6 3.084397927995807e-5 1.771649493359909e-5 5295/4893/5335/7316/867/3320/6233/2885/7311/1956/3845/3265/7314 13 Zaire_ebolavirus R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 15/1454 32/10654 5.683719772001805e-6 3.084397927995807e-5 1.771649493359909e-5 892/7027/54778/7316/1024/6667/4609/22938/3065/4087/6233/7311/25937/904/7314 15 Zaire_ebolavirus R-HSA-6804757 Regulation of TP53 Degradation 16/1454 36/10654 6.564587059006997e-6 3.547130947334682e-5 2.0374390375142563e-5 5170/1029/11200/472/7316/80196/983/1616/7157/6233/2475/7311/7874/7314/253260/4193 16 Zaire_ebolavirus R-HSA-5357786 TNFR1-induced proapoptotic signaling 9/1454 13/10654 6.832716692193122e-6 3.673821738487893e-5 2.1102090500741462e-5 7124/7186/8737/7375/841/27005/7128/8772/1540 9 Zaire_ebolavirus R-HSA-9613829 Chaperone Mediated Autophagy 12/1454 22/10654 6.857411505517513e-6 3.673821738487893e-5 2.1102090500741462e-5 2670/1080/10013/7316/3920/3320/6233/7311/200894/7431/3312/7314 12 Zaire_ebolavirus R-HSA-5578749 Transcriptional regulation by small RNAs 32/1454 106/10654 7.208521455652367e-6 3.845562929095903e-5 2.2088555932351365e-5 23165/27161/81929/5903/55706/7175/9631/5430/27327/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/5437/23225/5901/8086/9972/8021/6396/129401/55746/8480/10526 32 Zaire_ebolavirus R-HSA-110320 Translesion Synthesis by POLH 11/1454 19/10654 7.767845056204482e-6 4.126462837874027e-5 2.3702018892349447e-5 6118/7316/5111/7415/6119/25898/6233/7311/6117/5981/7314 11 Zaire_ebolavirus R-HSA-72306 tRNA processing 32/1454 107/10654 8.959611197124679e-6 4.739559032428559e-5 2.722358643266101e-5 23165/81929/5903/115708/55706/7175/9631/3028/348995/79023/57122/23636/10762/23511/54901/53371/54931/23279/4927/9688/55644/79902/9883/23225/5901/8086/9972/8021/6396/129401/55746/8480 32 Zaire_ebolavirus R-HSA-5621481 C-type lectin receptors (CLRs) 39/1454 142/10654 9.604087660597953e-6 5.0592244203735656e-5 2.905971470086234e-5 8454/1147/5170/8945/4893/4773/4790/6885/7321/3553/9039/6500/29108/841/8517/7316/64581/7335/5970/4792/6714/7322/1387/4067/23291/2534/2033/9040/7189/6233/7311/5971/3845/7334/3265/3551/997/4791/7314 39 Zaire_ebolavirus R-HSA-2173788 Downregulation of TGF-beta receptor signaling 13/1454 26/10654 9.93654329415371e-6 5.212545003058134e-5 2.994037387317368e-5 57154/10273/64750/7316/5501/23327/7046/9958/4087/6233/7514/7311/7314 13 Zaire_ebolavirus R-HSA-6806003 Regulation of TP53 Expression and Degradation 16/1454 37/10654 1.0109332428575633e-5 5.2811823765878515e-5 3.0334620565326314e-5 5170/1029/11200/472/7316/80196/983/1616/7157/6233/2475/7311/7874/7314/253260/4193 16 Zaire_ebolavirus R-HSA-177929 Signaling by EGFR 19/1454 49/10654 1.0445086701579676e-5 5.434034775739179e-5 3.121259053495101e-5 5295/4893/5335/7316/102/6714/867/9146/1445/998/6233/2885/7311/1956/3845/3265/5781/10254/7314 19 Zaire_ebolavirus R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 26/1454 80/10654 1.1965573874298334e-5 6.199447534050042e-5 3.5609050256196466e-5 8454/8945/11065/246184/7321/991/8697/6500/8881/7316/891/983/51433/51529/7324/64682/29945/10393/6233/51434/51343/7311/5347/29882/7314/996 26 Zaire_ebolavirus R-HSA-2424491 DAP12 signaling 14/1454 30/10654 1.2475815038376472e-5 6.41104127890448e-5 3.6824425054198224e-5 5295/4893/5335/7305/567/2534/22914/2885/7410/3932/5296/3845/3265/5879 14 Zaire_ebolavirus R-HSA-4090294 SUMOylation of intracellular receptors 14/1454 30/10654 1.2475815038376472e-5 6.41104127890448e-5 3.6824425054198224e-5 7068/5468/51588/6613/4929/9759/7341/10401/2908/7329/7376/6612/9063/8554 14 Zaire_ebolavirus R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 12/1454 23/10654 1.2559837377153638e-5 6.42798181212863e-5 3.6921729902030595e-5 6885/8517/7316/7335/64127/7189/5609/6233/7311/5599/7334/7314 12 Zaire_ebolavirus R-HSA-1236394 Signaling by ERBB4 21/1454 58/10654 1.2715730637134737e-5 6.481418976580014e-5 3.7228668006441784e-5 5295/4893/2670/23385/6776/7316/9611/11059/4734/10413/6714/83737/6285/6233/2885/7311/1956/3845/3265/5663/7314 21 Zaire_ebolavirus R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 8/1454 11/10654 1.3283634573108812e-5 6.743587067558062e-5 3.8734537146543945e-5 6885/7098/7316/7189/6233/7311/7314/148022 8 Zaire_ebolavirus R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 16/1454 38/10654 1.5263489383754735e-5 7.717563507689643e-5 4.432896726543861e-5 1912/6597/196528/8535/6045/80012/865/28996/1457/1911/6603/84733/2033/57332/861/6015 16 Zaire_ebolavirus R-HSA-195258 RHO GTPase Effectors 72/1454 327/10654 1.8373687263201083e-5 9.252988905748065e-5 5.31483079992385e-5 26999/5905/5170/25/81929/5590/5903/55143/5579/1495/1499/9735/7531/5747/4690/991/10006/7532/10971/10458/4771/5578/9212/389/1027/3619/1080/7533/2810/348995/79023/10381/57122/6280/30851/7534/332/3688/5501/5216/10152/6714/23279/79902/1062/7846/347733/22919/79784/9475/3895/10376/998/23028/2885/10096/7514/6093/57120/9928/10383/5347/5300/6396/5600/5586/55746/7280/7529/10787/5879/5595 72 Zaire_ebolavirus R-HSA-8878166 Transcriptional regulation by RUNX2 34/1454 121/10654 2.0868088863288195e-5 1.046730035015133e-4 6.012320003807502e-5 8454/57154/8493/7291/25/10273/3280/6500/100526737/10013/3958/3678/7316/9978/891/865/11059/9759/983/1026/10413/6772/6714/6502/2908/55294/23314/861/6233/7525/7311/25937/7314/5595 34 Zaire_ebolavirus R-HSA-5683057 MAPK family signaling cascades 66/1454 294/10654 2.137216452087973e-5 1.0677601242772849e-4 6.133114881305086e-5 27161/2674/4893/1437/3667/3561/5747/3815/7010/1439/2322/3315/27327/409/5908/10817/2064/5921/8452/4684/7316/9978/3560/4233/983/5597/84078/3718/6714/4609/2261/3558/3717/2534/408/1445/998/1847/3563/1739/6233/2885/3716/8660/7514/7311/5155/1956/4254/5896/4140/4343/3570/3845/3265/3559/369/7297/5781/3569/7529/7314/3572/5879/28956/5595 66 Zaire_ebolavirus R-HSA-6783783 Interleukin-10 signaling 18/1454 47/10654 2.1731283412178724e-5 1.0729288555267848e-4 6.162803593051304e-5 729230/7124/3592/1437/3587/3593/3553/2357/6774/1435/1440/3627/942/3716/6347/7297/3569/3586 18 Zaire_ebolavirus R-HSA-73762 RNA Polymerase I Transcription Initiation 18/1454 47/10654 2.1731283412178724e-5 1.0729288555267848e-4 6.162803593051304e-5 9112/9219/404672/2966/5928/5437/57459/2965/54815/2068/3066/3065/2071/1107/2968/57504/2967/53615 18 Zaire_ebolavirus R-HSA-9020591 Interleukin-12 signaling 18/1454 47/10654 2.1731283412178724e-5 1.0729288555267848e-4 6.162803593051304e-5 3592/6627/9049/3593/6775/3595/5908/3717/3458/998/5478/4001/3716/3594/4507/6845/7297/3586 18 Zaire_ebolavirus R-HSA-450302 activated TAK1 mediates p38 MAPK activation 12/1454 24/10654 2.2006977820923904e-5 1.0780850224335874e-4 6.192420136381208e-5 6885/8517/7316/7335/7867/64127/7189/6233/7311/5600/7334/7314 12 Zaire_ebolavirus R-HSA-6783589 Interleukin-6 family signaling 12/1454 24/10654 2.2006977820923904e-5 1.0780850224335874e-4 6.192420136381208e-5 9021/6774/6772/867/3717/3716/3570/5008/7297/5781/3569/3572 12 Zaire_ebolavirus R-HSA-2467813 Separation of Sister Chromatids 47/1454 190/10654 2.581985511593215e-5 1.2599688988743633e-4 7.237144212421617e-5 5905/81929/5903/11065/55143/246184/9735/7321/991/8697/9212/3619/23244/348995/79023/10381/57122/332/23047/8881/7316/5501/23279/51433/79902/1062/7846/347733/22919/10376/51529/7324/64682/29945/10393/6233/51434/7514/7311/10383/5347/29882/6396/55746/7280/7314/996 47 Zaire_ebolavirus R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 13/1454 28/10654 2.7419019608176712e-5 1.3328396018028756e-4 7.655706755056858e-5 10694/5203/10381/7203/10576/908/7846/347733/10574/10383/10693/7280/5201 13 Zaire_ebolavirus R-HSA-6807004 Negative regulation of MET activity 11/1454 21/10654 2.786510099520397e-5 1.349313928960069e-4 7.75033375858507e-5 5770/7316/4233/867/9146/5771/6233/2885/7311/10254/7314 11 Zaire_ebolavirus R-HSA-9020702 Interleukin-1 signaling 30/1454 103/10654 2.9780619809368952e-5 1.43654407432933e-4 8.251375603563811e-5 8454/1147/8945/351/4790/6885/3553/8878/6500/8517/4615/7316/9978/79155/7335/5970/4792/4793/3146/64127/23291/7189/6285/6233/7311/7334/3551/4791/7314/3556 30 Zaire_ebolavirus R-HSA-2871796 FCERI mediated MAPK activation 14/1454 32/10654 3.0967680882364904e-5 1.4768299329885384e-4 8.482773830217182e-5 4893/5335/4214/4067/5609/2885/7410/7409/2353/3845/5599/3265/5879/5595 14 Zaire_ebolavirus R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 14/1454 32/10654 3.0967680882364904e-5 1.4768299329885384e-4 8.482773830217182e-5 10694/5203/10381/7203/10576/908/7846/347733/10376/10574/10383/10693/7280/5201 14 Zaire_ebolavirus R-HSA-5656169 Termination of translesion DNA synthesis 14/1454 32/10654 3.0967680882364904e-5 1.4768299329885384e-4 8.482773830217182e-5 6118/9636/7706/7316/5111/6119/51455/9246/6233/7311/7318/6117/5981/7314 14 Zaire_ebolavirus R-HSA-5654741 Signaling by FGFR3 16/1454 40/10654 3.296828659156162e-5 1.5663046346707952e-4 8.996708197975305e-5 5295/4893/5335/10817/7316/6714/2261/867/6233/2885/7311/3845/3265/5781/7314/5595 16 Zaire_ebolavirus R-HSA-5675482 Regulation of necroptotic cell death 10/1454 18/10654 3.3463227511297936e-5 1.583842234463312e-4 9.097442540665485e-5 7186/8737/841/7316/8837/6233/7311/8772/8743/7314 10 Zaire_ebolavirus R-HSA-3371511 HSF1 activation 8/1454 12/10654 3.506366886521049e-5 1.6487986425519605e-4 9.470546109553921e-5 6118/7531/10013/7415/6119/3320/6117/3297 8 Zaire_ebolavirus R-HSA-168273 Influenza Viral RNA Transcription and Replication 36/1454 134/10654 3.509754060396548e-5 1.6487986425519605e-4 9.470546109553921e-5 23165/81929/5903/55706/7175/9631/3843/5430/348995/79023/57122/23636/10762/23511/53371/5611/23279/4927/9688/79902/6130/9883/5437/23225/3320/8086/6233/7311/6223/9972/8021/6396/129401/55746/6170/8480 36 Zaire_ebolavirus R-HSA-4419969 Depolymerisation of the Nuclear Lamina 9/1454 15/10654 3.6919826846787846e-5 1.7026396337035127e-4 9.7798037569860215e-005 4000/5579/5578/891/983/2010/4001/23592/7112 9 Zaire_ebolavirus R-HSA-5358508 Mismatch Repair 9/1454 15/10654 3.6919826846787846e-5 1.7026396337035127e-4 9.7798037569860215e-005 6118/4436/9156/2956/4292/5111/6119/6117/4437 9 Zaire_ebolavirus R-HSA-5637810 Constitutive Signaling by EGFRvIII 9/1454 15/10654 3.6919826846787846e-5 1.7026396337035127e-4 9.7798037569860215e-005 5295/4893/5335/867/3320/2885/1956/3845/3265 9 Zaire_ebolavirus R-HSA-5637812 Signaling by EGFRvIII in Cancer 9/1454 15/10654 3.6919826846787846e-5 1.7026396337035127e-4 9.7798037569860215e-005 5295/4893/5335/867/3320/2885/1956/3845/3265 9 Zaire_ebolavirus R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 9/1454 15/10654 3.6919826846787846e-5 1.7026396337035127e-4 9.7798037569860215e-005 7316/4233/867/9146/6233/2885/7311/10254/7314 9 Zaire_ebolavirus R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 12/1454 25/10654 3.7081931388741366e-5 1.7038741466578606e-4 9.786894684619791e-5 10694/10381/7203/10576/908/7846/347733/10376/10574/10383/10693/7280 12 Zaire_ebolavirus R-HSA-109606 Intrinsic Pathway for Apoptosis 19/1454 53/10654 3.835999527979723e-5 1.7561903293550804e-4 1.0087393974055766e-4 10018/7531/1029/7027/7532/10971/7533/2810/841/7534/6774/4836/836/3002/7157/8626/5599/7529/5595 19 Zaire_ebolavirus R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 23/1454 72/10654 5.113860212166588e-5 2.3243140819919616e-4 1.335064398920177e-4 8773/10890/7531/7532/10971/57186/7533/2810/10381/7534/5872/8766/7846/347733/10376/5867/6844/4012/10383/7280/7529/5879/57148 23 Zaire_ebolavirus R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 23/1454 72/10654 5.113860212166588e-5 2.3243140819919616e-4 1.335064398920177e-4 11065/246184/7321/991/8697/9212/8881/7316/51433/6502/51529/7324/64682/29945/10393/6233/51434/51343/7311/5347/29882/7314/996 23 Zaire_ebolavirus R-HSA-166520 Signaling by NTRKs 29/1454 101/10654 5.370001286725754e-5 2.4232371397805465e-4 1.3918848835995444e-4 5295/1173/4893/3667/5335/10817/6774/57498/6714/26052/7867/4914/2534/2885/1398/5900/8660/163/6196/5296/3845/5600/3265/1399/5781/4916/7529/5879/5595 29 Zaire_ebolavirus R-HSA-2219528 PI3K/AKT Signaling in Cancer 29/1454 101/10654 5.370001286725754e-5 2.4232371397805465e-4 1.3918848835995444e-4 5295/1147/5170/3667/3815/1027/2064/2100/4233/1026/6714/8503/2261/2534/5728/942/2885/2475/7409/8660/3932/5155/1956/4254/5296/5781/5879/253260/4193 29 Zaire_ebolavirus R-HSA-983705 Signaling by the B Cell Receptor (BCR) 31/1454 112/10654 6.520217848669632e-5 2.9317693826696664e-4 1.6839810759533972e-4 5295/8454/1147/5777/8945/4893/4773/4790/6885/5579/5966/4690/6500/8517/7316/5970/4792/4793/4067/23291/2534/5478/6233/2885/7409/7311/3845/3265/3551/7314/6786 31 Zaire_ebolavirus R-HSA-6804758 Regulation of TP53 Activity through Acetylation 13/1454 30/10654 6.725564257867176e-5 3.0133400002330156e-4 1.7308344802977147e-4 23774/9219/5928/57459/54815/2033/3066/3065/7157/1107/5371/5300/53615 13 Zaire_ebolavirus R-HSA-9639288 Amino acids regulate mTORC1 19/1454 55/10654 6.898846226278602e-5 3.080016808115163e-4 1.7691330188329224e-4 81929/55846/54468/11133/23334/79726/9681/527/525/84219/6009/8131/2475/55004/6396/57521/10641/28956/9296 19 Zaire_ebolavirus R-HSA-187687 Signalling to ERKs 14/1454 34/10654 7.004220081037063e-5 3.1160116897617176e-4 1.7898081441965639e-4 4893/57498/6714/7867/4914/2885/1398/5900/3845/5600/3265/1399/7529/5595 14 Zaire_ebolavirus R-HSA-8877330 RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) 7/1454 10/10654 7.153705041047453e-5 3.1713079741826564e-4 1.8215698158634546e-4 4773/865/3558/50943/3458/861/3559 7 Zaire_ebolavirus R-HSA-1295596 Spry regulation of FGF signaling 9/1454 16/10654 7.416487366072902e-5 3.259261573285842e-4 1.8720895454599502e-4 7316/6714/867/6233/2885/7311/5781/7314/5595 9 Zaire_ebolavirus R-HSA-205043 NRIF signals cell death from the nucleus 9/1454 16/10654 7.416487366072902e-5 3.259261573285842e-4 1.8720895454599502e-4 8878/23385/7316/7189/6233/7311/5599/5663/7314 9 Zaire_ebolavirus R-HSA-453279 Mitotic G1-G1/S phases 38/1454 149/10654 7.42977022663254e-5 3.259261573285842e-4 1.8720895454599502e-4 8454/6118/25/5000/1029/7027/8317/1027/6500/7153/898/4173/7316/5422/891/5753/993/983/1026/5111/6714/4171/4609/6119/5928/4067/3717/6502/990/4175/3065/6233/7311/6117/5001/7083/4176/7314 38 Zaire_ebolavirus R-HSA-209543 p75NTR recruits signalling complexes 8/1454 13/10654 8.023319234203794e-5 3.5074162902300616e-4 2.0146273077112595e-4 8878/4615/7316/7189/6233/7311/3551/7314 8 Zaire_ebolavirus R-HSA-9614085 FOXO-mediated transcription 21/1454 65/10654 8.923013097850941e-5 3.887222660966898e-4 2.2327845559000532e-4 857/10018/7532/10971/1027/2810/4287/7534/114907/1026/84676/1387/2908/2033/3630/3066/3065/4087/56729/23411/7529 21 Zaire_ebolavirus R-HSA-2122948 Activated NOTCH1 Transmits Signal to the Nucleus 13/1454 31/10654 1.0145264429351542e-4 4.404444109156411e-4 2.529871746992562e-4 142678/409/23385/7316/8650/102/408/83737/6233/7311/4851/5663/7314 13 Zaire_ebolavirus R-HSA-114604 GPVI-mediated activation cascade 14/1454 35/10654 1.0218893426415739e-4 4.421163856995675e-4 2.539475414703423e-4 5295/5170/5777/5590/8503/4067/2534/998/7410/7409/3932/5296/5781/5879 14 Zaire_ebolavirus R-HSA-75153 Apoptotic execution phase 18/1454 52/10654 1.033671742785927e-4 4.456824397833843e-4 2.5599584978151834e-4 4000/3837/1676/1499/5747/118/1829/841/100506658/5339/3146/836/4001/3836/6093/1677/7431/6304 18 Zaire_ebolavirus R-HSA-5213460 RIPK1-mediated regulated necrosis 10/1454 20/10654 1.0889406768106945e-4 4.6490445634895535e-4 2.6703679738450094e-4 7186/8737/841/7316/8837/6233/7311/8772/8743/7314 10 Zaire_ebolavirus R-HSA-5218859 Regulated Necrosis 10/1454 20/10654 1.0889406768106945e-4 4.6490445634895535e-4 2.6703679738450094e-4 7186/8737/841/7316/8837/6233/7311/8772/8743/7314 10 Zaire_ebolavirus R-HSA-187037 Signaling by NTRK1 (TRKA) 24/1454 80/10654 1.0893313313974728e-4 4.6490445634895535e-4 2.6703679738450094e-4 5295/1173/4893/3667/5335/6774/57498/6714/26052/7867/4914/2885/1398/5900/8660/163/6196/5296/3845/5600/3265/1399/7529/5595 24 Zaire_ebolavirus R-HSA-69231 Cyclin D associated events in G1 16/1454 44/10654 1.2782454329340656e-4 5.418555555771005e-4 3.1123679334598727e-4 8454/25/1029/7027/1027/6500/7316/5753/1026/6714/4067/3717/6502/6233/7311/7314 16 Zaire_ebolavirus R-HSA-69236 G1 Phase 16/1454 44/10654 1.2782454329340656e-4 5.418555555771005e-4 3.1123679334598727e-4 8454/25/1029/7027/1027/6500/7316/5753/1026/6714/4067/3717/6502/6233/7311/7314 16 Zaire_ebolavirus R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 25/1454 86/10654 1.3851656089664016e-4 5.833367841150849e-4 3.350632253560164e-4 5295/26999/25/5335/5747/4690/10006/10458/4771/10152/6714/4067/3320/2534/998/2885/7525/1398/7410/10096/7409/5296/10787/5879/5595 25 Zaire_ebolavirus R-HSA-9034015 Signaling by NTRK3 (TRKC) 9/1454 17/10654 1.3853669455949992e-4 5.833367841150849e-4 3.350632253560164e-4 5295/4893/3667/5335/6714/2885/3845/3265/4916 9 Zaire_ebolavirus R-HSA-186797 Signaling by PDGF 19/1454 58/10654 1.5532111843692816e-4 6.518309603736418e-4 3.7440564339006894e-4 5295/4893/5335/4690/5921/6778/6776/6774/6772/6714/2885/1398/5155/5296/3845/6777/3265/1399/5781 19 Zaire_ebolavirus R-HSA-5684996 MAPK1/MAPK3 signaling 56/1454 255/10654 1.6380440207195104e-4 6.825161428900934e-4 3.9203092693908633e-4 2674/4893/1437/3667/3561/5747/3815/7010/1439/2322/409/5908/10817/2064/5921/8452/4684/7316/9978/3560/4233/983/84078/3718/6714/2261/3558/3717/2534/408/1445/1847/3563/1739/6233/2885/3716/8660/7311/5155/1956/4254/4140/3570/3845/3265/3559/369/7297/5781/3569/7529/7314/3572/28956/5595 56 Zaire_ebolavirus R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 8/1454 14/10654 1.6480135618632917e-4 6.825161428900934e-4 3.9203092693908633e-4 6118/4436/9156/2956/4292/5111/6119/6117 8 Zaire_ebolavirus R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 8/1454 14/10654 1.6480135618632917e-4 6.825161428900934e-4 3.9203092693908633e-4 6118/4436/9156/4292/5111/6119/6117/4437 8 Zaire_ebolavirus R-HSA-8983432 Interleukin-15 signaling 8/1454 14/10654 1.6480135618632917e-4 6.825161428900934e-4 3.9203092693908633e-4 3561/6776/3560/6774/3718/2885/3716/6777 8 Zaire_ebolavirus R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 7/1454 11/10654 1.734805281258649e-4 7.114396902620974e-4 4.0864434363953084e-4 3091/1387/2033/25994/2056/2034/405 7 Zaire_ebolavirus R-HSA-8934903 Receptor Mediated Mitophagy 7/1454 11/10654 1.734805281258649e-4 7.114396902620974e-4 4.0864434363953084e-4 9140/9474/192111/1457/6714/81631/84557 7 Zaire_ebolavirus R-HSA-9020956 Interleukin-27 signaling 7/1454 11/10654 1.734805281258649e-4 7.114396902620974e-4 4.0864434363953084e-4 821/6774/6772/3717/3716/7297/3572 7 Zaire_ebolavirus R-HSA-5218921 VEGFR2 mediated cell proliferation 10/1454 21/10654 1.8255676466822049e-4 7.438154262695456e-4 4.2724066539624414e-4 5170/5590/4893/5335/5579/5578/5921/6714/3845/3265 10 Zaire_ebolavirus R-HSA-5621575 CD209 (DC-SIGN) signaling 10/1454 21/10654 1.8255676466822049e-4 7.438154262695456e-4 4.2724066539624414e-4 4893/4790/5970/1387/4067/2534/2033/5971/3845/3265 10 Zaire_ebolavirus R-HSA-5654743 Signaling by FGFR4 15/1454 41/10654 1.9111631575994677e-4 7.761788436831387e-4 4.458299114671763e-4 5295/4893/5335/10817/7316/6714/867/6233/2885/7311/3845/3265/5781/7314/5595 15 Zaire_ebolavirus R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 19/1454 59/10654 2.0018331221669596e-4 8.103883925428302e-4 4.654795582767646e-4 257218/7319/7321/56852/7320/7336/7323/7316/5111/7415/7322/118424/7324/6233/7311/7334/3105/6596/7314 19 Zaire_ebolavirus R-HSA-8854691 Interleukin-20 family signaling 11/1454 25/10654 2.084679308288205e-4 8.385339454104953e-4 4.81646102167142e-4 6775/6776/6774/3718/6772/3717/3716/6777/6773/7297/5781 11 Zaire_ebolavirus R-HSA-9006115 Signaling by NTRK2 (TRKB) 11/1454 25/10654 2.084679308288205e-4 8.385339454104953e-4 4.81646102167142e-4 5295/4893/5335/10817/6714/2534/2885/3845/3265/5781/5879 11 Zaire_ebolavirus R-HSA-5205647 Mitophagy 12/1454 29/10654 2.1842441354337196e-4 8.730042433368422e-4 5.014455208163626e-4 9140/8878/9474/192111/7316/1457/6714/81631/6233/7311/84557/7314 12 Zaire_ebolavirus R-HSA-72086 mRNA Capping 12/1454 29/10654 2.1842441354337196e-4 8.730042433368422e-4 5.014455208163626e-4 5430/404672/4686/2966/8731/5437/2965/2068/2071/2968/2967/22916 12 Zaire_ebolavirus R-HSA-202403 TCR signaling 31/1454 119/10654 2.200319880559825e-4 8.738809872633501e-4 5.019491143764236e-4 5295/8454/1147/5170/8945/5335/4790/6885/4690/7321/6500/5788/8517/7316/7335/5970/4792/7322/23291/5728/1445/7189/6233/3702/7311/3932/5296/7334/3551/997/7314 31 Zaire_ebolavirus R-HSA-9612973 Autophagy 31/1454 119/10654 2.200319880559825e-4 8.738809872633501e-4 5.019491143764236e-4 2670/9140/22863/8878/1080/10533/10013/9474/192111/7316/1457/8678/6714/3920/3320/6009/55054/81631/6233/2475/55004/7311/84557/200894/55626/7251/7431/3312/57521/7314/28956 31 Zaire_ebolavirus R-HSA-211000 Gene Silencing by RNA 34/1454 136/10654 2.6210086774608503e-4 0.0010376886556362297 5.960387161256551e-4 23165/27161/81929/5903/55706/7175/9631/5430/27327/348995/79023/57122/23636/10762/23511/53371/23279/4927/9688/79902/9883/5437/23225/3320/5901/8086/9972/8021/6396/129401/55746/23405/8480/10526 34 Zaire_ebolavirus R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 29/1454 110/10654 2.783926182695903e-4 0.0010987345028257497 6.311028831915806e-4 11065/4790/246184/1029/7321/8697/1027/8881/7316/6774/5970/1026/51433/51529/7324/64682/29945/10393/6233/51434/2353/51343/6196/7311/29882/3569/7314/996/5595 29 Zaire_ebolavirus R-HSA-2500257 Resolution of Sister Chromatid Cohesion 32/1454 126/10654 2.896596917948022e-4 0.001139629849905175 6.545927903389116e-4 5905/81929/5903/55143/9735/991/9212/3619/23244/348995/79023/9133/10381/57122/332/23047/891/5501/983/23279/79902/1062/7846/347733/22919/10376/7514/10383/5347/6396/55746/7280 32 Zaire_ebolavirus R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 8/1454 15/10654 3.1095167543151834e-4 0.0012158017371685765 6.983452141923932e-4 6737/29110/7316/22954/3661/6233/7311/7314 8 Zaire_ebolavirus R-HSA-844456 The NLRP3 inflammasome 8/1454 15/10654 3.1095167543151834e-4 0.0012158017371685765 6.983452141923932e-4 834/351/4790/10910/29108/5970/114548/4791 8 Zaire_ebolavirus R-HSA-9607240 FLT3 Signaling 57/1454 267/10654 3.1330873106344046e-4 0.0012212250538974352 7.014603168994087e-4 5295/54106/5170/2674/4893/1437/3667/3561/5747/3815/7010/1439/2322/409/5908/10817/2064/5921/8452/6776/4684/7316/9978/3560/4233/84078/3718/6714/2261/3558/3717/2534/408/1445/1847/3563/1739/6233/2885/3716/8660/7311/5155/1956/4254/5296/4140/3845/6777/3265/3559/369/5781/7529/7314/28956/5595 57 Zaire_ebolavirus R-HSA-114452 Activation of BH3-only proteins 12/1454 30/10654 3.192035941865051e-4 0.0012403621144469444 7.124524665566244e-4 10018/7531/7027/7532/10971/7533/2810/7534/7157/8626/5599/7529 12 Zaire_ebolavirus R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 22/1454 76/10654 3.648053163197446e-4 0.0014131996715278721 8.117287524264438e-4 11065/246184/7321/991/8697/8881/7316/891/983/51433/51529/7324/64682/29945/10393/6233/51434/7311/5347/29882/7314/996 22 Zaire_ebolavirus R-HSA-389359 CD28 dependent Vav1 pathway 7/1454 12/10654 3.672641310907807e-4 0.0014183605553475243 8.146931161103207e-4 2534/998/942/2885/7409/3932/5879 7 Zaire_ebolavirus R-HSA-6804760 Regulation of TP53 Activity through Methylation 9/1454 19/10654 4.070470198393727e-4 0.001567193265987065 9.001812413637503e-4 11200/472/7316/2033/7157/6233/7311/7314/4193 9 Zaire_ebolavirus R-HSA-8953750 Transcriptional Regulation by E2F6 13/1454 35/10654 4.279608200452076e-4 0.0016426910745027939 9.435464806516611e-4 23468/5888/7027/2146/8317/6045/80012/1911/5928/1111/672/7703/6015 13 Zaire_ebolavirus R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 21/1454 72/10654 4.3995447033462107e-4 0.0016835947664172886 9.670411809946717e-4 11065/246184/7321/8697/898/8881/7316/51433/990/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/7314/996 21 Zaire_ebolavirus R-HSA-5693606 DNA Double Strand Break Response 22/1454 77/10654 4.460232356721398e-4 0.0017003795872002803 9.766822259994084e-4 25/3838/51588/11200/472/7336/580/7316/9656/7341/165918/7157/7329/8924/6233/672/7158/7311/9025/5599/7334/7314 22 Zaire_ebolavirus R-HSA-2871837 FCERI mediated NF-kB activation 23/1454 82/10654 4.4704181363248036e-4 0.0017003795872002803 9.766822259994084e-4 8454/1147/5170/8945/4790/6885/7321/6500/8517/7316/7335/5970/4792/7322/4067/23291/7189/6233/7311/7334/3551/997/7314 23 Zaire_ebolavirus R-HSA-112409 RAF-independent MAPK1/3 activation 10/1454 23/10654 4.568834705804913e-4 0.0017325791851230076 9.951773756778615e-4 983/3717/1847/3716/3570/7297/5781/3569/3572/5595 10 Zaire_ebolavirus R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway 11/1454 27/10654 4.6963100557972687e-4 0.001775571879954583 0.0010198719798744187 7186/219699/8737/841/7099/836/8837/8772/26060/8743/148022 11 Zaire_ebolavirus R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 27/1454 103/10654 4.91232219169412e-4 0.0018516807303421846 0.0010635881959325118 5295/3643/3667/3815/2064/4615/2100/4233/6714/8503/2261/2534/3630/942/7189/2885/7409/8660/3932/5155/1956/4254/5296/5781/5879/5595/3556 27 Zaire_ebolavirus R-HSA-202424 Downstream TCR signaling 26/1454 98/10654 5.076013599348105e-4 0.001907671976590825 0.0010957490472119867 5295/8454/1147/5170/8945/4790/6885/7321/6500/8517/7316/7335/5970/4792/7322/23291/5728/7189/6233/7311/3932/5296/7334/3551/997/7314 26 Zaire_ebolavirus R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 19/1454 63/10654 5.124629311608957e-4 0.001920210804558237 0.0011029512334195968 11065/246184/7321/8697/8881/7316/51433/51529/7324/64682/29945/10393/6233/51434/51343/7311/29882/7314/996 19 Zaire_ebolavirus R-HSA-5654738 Signaling by FGFR2 21/1454 73/10654 5.395528738481836e-4 0.002011321469792428 0.0011552843524496453 5295/4893/5335/5430/3178/10817/4686/7316/6714/867/5437/7072/6233/2885/7311/3845/3265/5781/22916/7314/5595 21 Zaire_ebolavirus R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 23/1454 83/10654 5.399735161158386e-4 0.002011321469792428 0.0011552843524496453 8454/1147/8945/4893/4773/4790/6885/5579/5966/6500/8517/7316/5970/4792/4793/23291/5478/6233/7311/3845/3265/3551/7314 23 Zaire_ebolavirus R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 8/1454 16/10654 5.47738477202309e-4 0.002028243361169727 0.0011650041295293693 57154/5590/7316/7046/6233/7311/56288/7314 8 Zaire_ebolavirus R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 8/1454 16/10654 5.47738477202309e-4 0.002028243361169727 0.0011650041295293693 6885/7099/7316/7189/6233/7311/7314/148022 8 Zaire_ebolavirus R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 13/1454 36/10654 5.87106022369509e-4 0.002167643642707366 0.0012450743552025088 26999/25/5747/4690/10006/10458/10152/998/2885/10096/10787/5879/5595 13 Zaire_ebolavirus R-HSA-69206 G1/S Transition 32/1454 131/10654 6.071616879801814e-4 0.002235136155459206 0.0012838414270310394 8454/6118/5000/7027/8317/1027/6500/898/4173/7316/5422/891/5753/993/983/1026/5111/4171/4609/6119/5928/6502/990/4175/3065/6233/7311/6117/5001/7083/4176/7314 32 Zaire_ebolavirus R-HSA-69190 DNA strand elongation 12/1454 32/10654 6.409612969295861e-4 0.0023458438163789213 0.001347430878184289 6118/2237/1763/4173/5422/5111/4171/6119/4175/6117/5981/4176 12 Zaire_ebolavirus R-HSA-8941326 RUNX2 regulates bone development 12/1454 32/10654 6.409612969295861e-4 0.0023458438163789213 0.001347430878184289 25/3280/100526737/10013/865/9759/10413/6714/23314/7525/25937/5595 12 Zaire_ebolavirus R-HSA-199418 Negative regulation of the PI3K/AKT network 28/1454 110/10654 6.500296842732688e-4 0.0023619505576791184 0.0013566824406383965 5295/3643/3667/3815/2064/4615/2100/4233/6714/8503/2261/2534/5728/3630/942/7189/2885/7409/8660/3932/5155/1956/4254/5296/5781/5879/5595/3556 28 Zaire_ebolavirus R-HSA-167044 Signalling to RAS 9/1454 20/10654 6.509903443325291e-4 0.0023619505576791184 0.0013566824406383965 4893/6714/7867/4914/2885/5900/3845/5600/3265 9 Zaire_ebolavirus R-HSA-622312 Inflammasomes 9/1454 20/10654 6.509903443325291e-4 0.0023619505576791184 0.0013566824406383965 834/9447/351/4790/10910/29108/5970/114548/4791 9 Zaire_ebolavirus R-HSA-202733 Cell surface interactions at the vascular wall 33/1454 137/10654 6.559177605468952e-4 0.0023729898291050032 0.0013630232955103357 5295/3675/5777/4893/857/5335/960/483/5175/3684/7010/4680/3678/3688/8140/6714/4067/682/2534/1088/5478/6520/2885/7525/3685/3932/5296/3687/3845/3265/5781/6566/3655 33 Zaire_ebolavirus R-HSA-8940973 RUNX2 regulates osteoblast differentiation 10/1454 24/10654 6.881873130842813e-4 0.0024826012239917198 0.0014259830616465126 25/3280/10013/865/10413/6714/23314/7525/25937/5595 10 Zaire_ebolavirus R-HSA-171007 p38MAPK events 7/1454 13/10654 7.021335596309789e-4 0.0025113242942483025 0.001442481326155749 4893/6714/7867/5900/3845/5600/3265 7 Zaire_ebolavirus R-HSA-2995383 Initiation of Nuclear Envelope Reformation 7/1454 13/10654 7.021335596309789e-4 0.0025113242942483025 0.001442481326155749 4000/23141/7444/2010/4001/23592/7112 7 Zaire_ebolavirus R-HSA-2995410 Nuclear Envelope Reassembly 7/1454 13/10654 7.021335596309789e-4 0.0025113242942483025 0.001442481326155749 4000/23141/7444/2010/4001/23592/7112 7 Zaire_ebolavirus R-HSA-388841 Costimulation by the CD28 family 20/1454 70/10654 7.978066296781794e-4 0.0028324805554561425 0.0016269504967170016 5295/5170/5777/5133/6714/8503/4067/2534/1445/998/942/2885/7525/2475/7409/3932/5296/5781/5879/253260 20 Zaire_ebolavirus R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 21/1454 75/10654 7.986740247711919e-4 0.0028324805554561425 0.0016269504967170016 11065/246184/7321/991/8697/8881/7316/891/983/51433/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 21 Zaire_ebolavirus R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 21/1454 75/10654 7.986740247711919e-4 0.0028324805554561425 0.0016269504967170016 5295/3667/3815/2064/2100/4233/6714/8503/2261/2534/942/2885/7409/8660/3932/5155/1956/4254/5296/5781/5879 21 Zaire_ebolavirus R-HSA-174437 Removal of the Flap Intermediate from the C-strand 6/1454 10/10654 8.209060951636606e-4 0.002862938431609553 0.0016444452176044171 6118/2237/1763/5111/6119/6117 6 Zaire_ebolavirus R-HSA-390450 Folding of actin by CCT/TriC 6/1454 10/10654 8.209060951636606e-4 0.002862938431609553 0.0016444452176044171 10694/7203/10576/908/10574/10693 6 Zaire_ebolavirus R-HSA-5602498 MyD88 deficiency (TLR2/4) 6/1454 10/10654 8.209060951636606e-4 0.002862938431609553 0.0016444452176044171 10333/7099/4615/7096/114609/7097 6 Zaire_ebolavirus R-HSA-74749 Signal attenuation 6/1454 10/10654 8.209060951636606e-4 0.002862938431609553 0.0016444452176044171 3643/3667/3630/2885/8660/5595 6 Zaire_ebolavirus R-HSA-8853334 Signaling by FGFR3 fusions in cancer 6/1454 10/10654 8.209060951636606e-4 0.002862938431609553 0.0016444452176044171 5295/4893/2261/2885/3845/3265 6 Zaire_ebolavirus R-HSA-937042 IRAK2 mediated activation of TAK1 complex 6/1454 10/10654 8.209060951636606e-4 0.002862938431609553 0.0016444452176044171 6885/7316/7189/6233/7311/7314 6 Zaire_ebolavirus R-HSA-8878159 Transcriptional regulation by RUNX3 25/1454 96/10654 8.673589731247716e-4 0.0030165882518344957 0.0017327002458177318 57154/1499/10018/1029/3280/64750/7316/865/9759/1026/10413/6714/4609/22938/1387/2033/7157/861/6233/7311/25937/3845/4851/7314/4193 25 Zaire_ebolavirus R-HSA-1980145 Signaling by NOTCH2 12/1454 33/10654 8.835827922777203e-4 0.003047755439664794 0.0017506023887376894 142678/3280/23385/7316/102/2033/3002/4853/6233/7311/5663/7314 12 Zaire_ebolavirus R-HSA-2559585 Oncogene Induced Senescence 12/1454 33/10654 8.835827922777203e-4 0.003047755439664794 0.0017506023887376894 1029/7027/27327/7316/6667/7157/6233/7311/4343/7314/5595/4193 12 Zaire_ebolavirus R-HSA-68962 Activation of the pre-replicative complex 12/1454 33/10654 8.835827922777203e-4 0.003047755439664794 0.0017506023887376894 6118/5000/8317/4173/5422/4171/6119/990/4175/6117/5001/4176 12 Zaire_ebolavirus R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand 8/1454 17/10654 9.114733951070278e-4 0.003118328816412359 0.001791139080201739 7186/8737/841/7099/8837/8772/8743/148022 8 Zaire_ebolavirus R-HSA-8934593 Regulation of RUNX1 Expression and Activity 8/1454 17/10654 9.114733951070278e-4 0.003118328816412359 0.001791139080201739 27161/27327/865/6714/861/5371/4343/5781 8 Zaire_ebolavirus R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 8/1454 17/10654 9.114733951070278e-4 0.003118328816412359 0.001791139080201739 6885/7099/7316/7189/6233/7311/7314/148022 8 Zaire_ebolavirus R-HSA-432722 Golgi Associated Vesicle Biogenesis 17/1454 56/10654 9.15265584661151e-4 0.0031228167238167726 0.0017937168924895472 27131/2512/9685/10618/6272/8546/2804/7037/3482/408/5878/6844/6845/64746/3312/8673/1362 17 Zaire_ebolavirus R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 18/1454 61/10654 9.485810984222929e-4 0.0032277394673342345 0.0018539835408708822 26999/25/5747/4690/10006/10458/4771/10152/3320/998/2885/1398/7410/10096/7409/10787/5879/5595 18 Zaire_ebolavirus R-HSA-5218920 VEGFR2 mediated vascular permeability 11/1454 29/10654 9.604748600667912e-4 0.003259401209768437 0.0018721697513573148 5170/857/1495/1499/1500/3320/7410/2475/7409/5879/253260 11 Zaire_ebolavirus R-HSA-5693565 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 21/1454 76/10654 9.643329861799341e-4 0.0032636968537648843 0.001874637129331111 25/51588/11200/472/7336/580/7316/9656/7341/165918/7157/7329/8924/6233/672/7158/7311/9025/5599/7334/7314 21 Zaire_ebolavirus R-HSA-983231 Factors involved in megakaryocyte development and platelet production 38/1454 168/10654 9.797944328817955e-4 0.003300450284115605 0.0018957479580179932 3443/23468/25/3441/11311/5868/23186/10019/10381/3449/3444/3659/2627/1062/3451/5889/3717/7846/5576/3448/347733/10376/3440/3066/3065/998/7157/23028/3835/10383/3452/5890/3456/10938/7280/3446/5879/3445 38 Zaire_ebolavirus R-HSA-5663220 RHO GTPases Activate Formins 33/1454 140/10654 9.804355887682577e-4 0.003300450284115605 0.0018957479580179932 5905/81929/5903/55143/9735/991/9212/389/3619/348995/79023/10381/57122/332/3688/5501/5216/6714/23279/79902/1062/7846/347733/22919/10376/998/7514/10383/5347/6396/55746/7280/5879 33 Zaire_ebolavirus R-HSA-445144 Signal transduction by L1 9/1454 21/10654 0.0010023155290807605 0.003365107336300473 0.0019328863676588979 3678/4684/3688/1457/7410/3685/1956/5879/5595 9 Zaire_ebolavirus R-HSA-210991 Basigin interactions 10/1454 25/10654 0.0010080002345879237 0.003375192274856904 0.0019386790626033134 3675/857/483/3688/8140/682/5478/6520/6566/3655 10 Zaire_ebolavirus R-HSA-111465 Apoptotic cleavage of cellular proteins 13/1454 38/10654 0.0010573368989756095 0.0035310004132899 0.0020281738087288667 4000/1499/5747/118/1829/841/100506658/5339/836/4001/6093/7431/6304 13 Zaire_ebolavirus R-HSA-2428928 IRS-related events triggered by IGF1R 16/1454 52/10654 0.0010923899388085515 0.0036384098755554667 0.0020898688052394176 5295/54106/5170/4893/3667/2322/2261/8471/2885/8660/3479/5296/3845/3265/5781/3480 16 Zaire_ebolavirus R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 20/1454 72/10654 0.0011749267897073709 0.0038927179690567896 0.002235941009775523 11065/246184/7321/991/8697/8881/7316/983/51433/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 20 Zaire_ebolavirus R-HSA-199992 trans-Golgi Network Vesicle Budding 20/1454 72/10654 0.0011749267897073709 0.0038927179690567896 0.002235941009775523 27131/8773/2512/351/9685/10618/6272/8546/2804/7037/9146/3482/408/5878/6844/6845/64746/3312/8673/1362 20 Zaire_ebolavirus R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 19/1454 67/10654 0.0011793361575368852 0.0038970714497085003 0.0022384416085863795 11065/246184/7321/991/8697/8881/7316/51433/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 19 Zaire_ebolavirus R-HSA-2172127 DAP12 interactions 14/1454 43/10654 0.0011956410424720464 0.003940607519561012 0.002263448322343058 5295/4893/5335/7305/567/2534/22914/2885/7410/3932/5296/3845/3265/5879 14 Zaire_ebolavirus R-HSA-2559580 Oxidative Stress Induced Senescence 30/1454 125/10654 0.0012019529500147054 0.003951067269108392 0.002269456305235956 1912/1029/7027/2146/8535/6045/27327/80012/7316/1911/7867/5928/84733/57332/7157/23135/5609/6233/2353/7311/4343/5599/5600/4217/3456/7314/6015/5595/4193/23043 30 Zaire_ebolavirus R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 7/1454 14/10654 0.0012394657630756317 0.004042713460394353 0.0023220970254512105 5861/9133/891/26003/983/5347/5595 7 Zaire_ebolavirus R-HSA-69166 Removal of the Flap Intermediate 7/1454 14/10654 0.0012394657630756317 0.004042713460394353 0.0023220970254512105 6118/2237/1763/5422/5111/6119/6117 7 Zaire_ebolavirus R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 7/1454 14/10654 0.0012394657630756317 0.004042713460394353 0.0023220970254512105 4893/5921/5753/1398/3845/3265/5879 7 Zaire_ebolavirus R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 23/1454 88/10654 0.00130120494364496 0.004233118925191227 0.0024314641541794847 8454/8945/7531/203068/7532/6500/9133/7316/891/983/10121/23291/7846/7283/3320/22919/1069/6233/7311/10383/5347/55755/7314 23 Zaire_ebolavirus R-HSA-180786 Extension of Telomeres 11/1454 30/10654 0.001331737171892217 0.004321281184052323 0.002482103736000958 6118/2237/7015/1763/5422/10856/5111/6119/8607/6117/5981 11 Zaire_ebolavirus R-HSA-2428924 IGF1R signaling cascade 16/1454 53/10654 0.0013698703668230993 0.00443359072449944 0.0025466132918616404 5295/54106/5170/4893/3667/2322/2261/8471/2885/8660/3479/5296/3845/3265/5781/3480 16 Zaire_ebolavirus R-HSA-68877 Mitotic Prometaphase 43/1454 200/10654 0.0014065347062701594 0.004540582551779823 0.002608068402719567 10844/5905/81929/5903/55143/9735/7531/991/203068/7532/9212/3619/23244/348995/79023/9133/10381/57122/332/23047/891/5501/1457/983/23279/10121/79902/1062/7846/7283/347733/3320/22919/10376/1069/7514/10383/5347/6396/27229/55746/7280/55755 43 Zaire_ebolavirus R-HSA-917937 Iron uptake and transport 17/1454 58/10654 0.0014127448491885845 0.004543610661250412 0.0026098077206463217 8454/2512/55240/4738/6500/7036/7316/527/525/23545/7037/55832/6233/7311/26234/7314/9296 17 Zaire_ebolavirus R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 20/1454 73/10654 0.0014146905315410338 0.004543610661250412 0.0026098077206463217 11065/246184/7321/991/8697/8881/7316/983/51433/51529/7324/64682/29945/10393/6233/51434/7311/29882/7314/996 20 Zaire_ebolavirus R-HSA-210993 Tie2 Signaling 8/1454 18/10654 0.0014457639819064887 0.004619839728985455 0.002653592988431092 5295/4893/7010/2885/5296/3845/3265/5781 8 Zaire_ebolavirus R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 8/1454 18/10654 0.0014457639819064887 0.004619839728985455 0.002653592988431092 4893/5578/2885/6196/1956/3845/3265/5595 8 Zaire_ebolavirus R-HSA-2979096 NOTCH2 Activation and Transmission of Signal to the Nucleus 9/1454 22/10654 0.0014927154577990592 0.004733825595387949 0.0027190654103352876 142678/23385/7316/102/4853/6233/7311/5663/7314 9 Zaire_ebolavirus R-HSA-389357 CD28 dependent PI3K/Akt signaling 9/1454 22/10654 0.0014927154577990592 0.004733825595387949 0.0027190654103352876 5295/5170/8503/2534/942/2475/3932/5296/253260 9 Zaire_ebolavirus R-HSA-5205685 Pink/Parkin Mediated Mitophagy 9/1454 22/10654 0.0014927154577990592 0.004733825595387949 0.0027190654103352876 9140/8878/9474/7316/81631/6233/7311/84557/7314 9 Zaire_ebolavirus R-HSA-174414 Processive synthesis on the C-strand of the telomere 6/1454 11/10654 0.0015978167756090155 0.00495480620810776 0.002845994619765086 6118/2237/1763/5111/6119/6117 6 Zaire_ebolavirus R-HSA-3371378 Regulation by c-FLIP 6/1454 11/10654 0.0015978167756090155 0.00495480620810776 0.002845994619765086 7186/8737/841/8837/8772/8743 6 Zaire_ebolavirus R-HSA-5218900 CASP8 activity is inhibited 6/1454 11/10654 0.0015978167756090155 0.00495480620810776 0.002845994619765086 7186/8737/841/8837/8772/8743 6 Zaire_ebolavirus R-HSA-5603041 IRAK4 deficiency (TLR2/4) 6/1454 11/10654 0.0015978167756090155 0.00495480620810776 0.002845994619765086 10333/7099/4615/7096/114609/7097 6 Zaire_ebolavirus R-HSA-5655291 Signaling by FGFR4 in disease 6/1454 11/10654 0.0015978167756090155 0.00495480620810776 0.002845994619765086 5295/4893/5335/2885/3845/3265 6 Zaire_ebolavirus R-HSA-69416 Dimerization of procaspase-8 6/1454 11/10654 0.0015978167756090155 0.00495480620810776 0.002845994619765086 7186/8737/841/8837/8772/8743 6 Zaire_ebolavirus R-HSA-8875555 MET activates RAP1 and RAC1 6/1454 11/10654 0.0015978167756090155 0.00495480620810776 0.002845994619765086 5908/4233/2885/1398/1399/5879 6 Zaire_ebolavirus R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 6/1454 11/10654 0.0015978167756090155 0.00495480620810776 0.002845994619765086 4893/10817/2885/3845/3265/5781 6 Zaire_ebolavirus R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 6/1454 11/10654 0.0015978167756090155 0.00495480620810776 0.002845994619765086 6885/7316/7189/6233/7311/7314 6